# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- PhoU PF01895.14 ETN97098.1 - 0.083 13.3 0.6 0.17 12.3 0.4 1.6 1 0 0 1 1 1 0 PhoU domain PPR PF01535.15 ETN97099.1 - 4.7e-07 29.3 0.6 0.019 14.9 0.0 2.3 2 0 0 2 2 2 2 PPR repeat PPR_2 PF13041.1 ETN97099.1 - 0.00011 22.0 0.8 0.021 14.8 0.1 2.2 2 0 0 2 2 2 2 PPR repeat family PPR_3 PF13812.1 ETN97099.1 - 0.024 14.8 0.0 1.2 9.5 0.0 2.2 2 0 0 2 2 2 0 Pentatricopeptide repeat domain DUF3636 PF12331.3 ETN97099.1 - 0.046 13.3 0.0 0.054 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3636) HEAT PF02985.17 ETN97100.1 - 2.2e-11 42.8 0.1 0.3 11.2 0.0 7.0 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 ETN97100.1 - 6.9e-09 35.8 0.0 6.8e-05 23.0 0.0 4.8 4 1 2 6 6 6 2 HEAT repeats Ank_4 PF13637.1 ETN97100.1 - 6.4e-05 23.3 0.5 0.0016 18.8 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETN97100.1 - 0.00016 21.5 0.0 0.0024 17.9 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.25 ETN97100.1 - 0.00078 19.1 0.0 0.0044 16.7 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat HEAT_EZ PF13513.1 ETN97100.1 - 0.00081 19.8 0.0 0.73 10.4 0.0 4.0 3 1 2 5 5 5 1 HEAT-like repeat Ank_2 PF12796.2 ETN97100.1 - 0.00092 19.5 0.0 0.0046 17.2 0.0 2.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETN97100.1 - 0.0046 17.1 0.0 0.016 15.4 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) IMP_cyclohyd PF07826.6 ETN97100.1 - 0.0053 16.1 0.0 0.02 14.2 0.0 1.9 2 0 0 2 2 2 1 IMP cyclohydrolase-like protein OMP_b-brl_3 PF14905.1 ETN97101.1 - 0.014 14.1 22.6 0.016 13.9 15.7 1.0 1 0 0 1 1 1 0 Outer membrane protein beta-barrel family DUF1943 PF09172.6 ETN97101.1 - 0.33 9.7 4.4 0.41 9.4 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Mucin PF01456.12 ETN97101.1 - 2.3 7.9 11.7 2.7 7.7 8.1 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein UBX PF00789.15 ETN97102.1 - 6.8e-09 35.6 0.2 1.3e-08 34.8 0.0 1.5 2 0 0 2 2 2 1 UBX domain WD40 PF00400.27 ETN97103.1 - 1.1e-76 250.1 21.5 1.5e-14 53.1 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETN97103.1 - 1.4e-08 33.5 3.2 0.00036 18.9 0.1 3.1 1 1 1 3 3 3 3 Cytochrome D1 heme domain PD40 PF07676.7 ETN97103.1 - 1.4e-08 34.1 8.9 1.8 8.3 0.0 7.3 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETN97103.1 - 5.7e-06 24.7 7.2 0.29 9.2 0.3 4.1 1 1 3 4 4 4 3 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETN97103.1 - 0.00062 19.1 0.3 5.6 6.1 0.0 4.1 1 1 0 3 3 3 2 Domain of unknown function (DUF4221) DPPIV_N PF00930.16 ETN97103.1 - 0.0016 17.1 0.0 4.3 5.8 0.0 3.6 3 1 1 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PQQ_2 PF13360.1 ETN97103.1 - 0.003 17.0 0.0 0.08 12.3 0.0 2.6 1 1 1 2 2 2 1 PQQ-like domain DUF1258 PF06869.7 ETN97103.1 - 0.02 13.9 3.5 0.081 11.9 0.0 3.3 3 1 2 5 5 5 0 Protein of unknown function (DUF1258) Nucleoporin_N PF08801.6 ETN97103.1 - 0.031 13.0 10.6 12 4.5 0.0 4.0 1 1 1 3 3 3 0 Nup133 N terminal like DUF727 PF05303.7 ETN97103.1 - 0.056 13.2 0.5 25 4.6 0.0 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF727) tRNA-synt_1c PF00749.16 ETN97104.1 - 1.5e-26 92.7 0.0 2.8e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 ETN97104.1 - 3.3e-25 88.7 0.3 6.3e-25 87.8 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain CLASP_N PF12348.3 ETN97105.1 - 0.038 13.3 0.5 0.066 12.5 0.1 1.5 2 0 0 2 2 2 0 CLASP N terminal WD40 PF00400.27 ETN97106.1 - 3.5e-55 182.0 26.3 9.8e-13 47.4 2.2 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETN97106.1 - 5.6e-11 41.2 9.0 4.2e-06 25.1 0.3 5.0 2 2 2 5 5 5 4 Nucleoporin Nup120/160 SSXT PF05030.7 ETN97106.1 - 0.039 13.5 0.0 0.098 12.2 0.0 1.6 1 0 0 1 1 1 0 SSXT protein (N-terminal region) Kinetocho_Slk19 PF12709.2 ETN97107.1 - 0.13 12.3 0.4 0.13 12.3 0.3 2.4 2 1 0 2 2 2 0 Central kinetochore-associated IGR PF09597.5 ETN97107.1 - 0.23 11.3 6.8 4.3 7.3 1.2 2.7 2 1 0 2 2 2 0 IGR protein motif Fzo_mitofusin PF04799.8 ETN97107.1 - 2.5 7.4 5.0 1.4 8.2 0.2 2.0 1 1 1 2 2 2 0 fzo-like conserved region FAM176 PF14851.1 ETN97108.1 - 0.16 11.6 1.0 0.27 10.9 0.7 1.3 1 0 0 1 1 1 0 FAM176 family SRP-alpha_N PF04086.8 ETN97108.1 - 0.93 8.8 12.1 1.4 8.2 8.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DDE_Tnp_IS1595 PF12762.2 ETN97110.1 - 1.2e-15 57.6 1.1 7.4e-14 51.8 0.8 2.4 1 1 0 1 1 1 1 ISXO2-like transposase domain HSDR_N_2 PF13588.1 ETN97110.1 - 0.0035 17.1 0.3 0.0088 15.8 0.0 1.8 2 0 0 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) rve_2 PF13333.1 ETN97110.1 - 0.026 14.5 2.2 0.08 13.0 0.6 2.2 2 0 0 2 2 2 0 Integrase core domain rve_3 PF13683.1 ETN97110.1 - 0.037 13.5 0.6 0.12 11.9 0.1 2.0 2 0 0 2 2 2 0 Integrase core domain BRCT PF00533.21 ETN97110.1 - 0.065 13.3 1.2 0.12 12.5 0.1 2.1 2 1 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Adenosine_kin PF04008.9 ETN97111.1 - 0.008 15.6 0.1 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Adenosine specific kinase Glyco_hydro_88 PF07470.8 ETN97112.1 - 0.097 11.6 1.6 0.11 11.4 1.1 1.0 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 GTP_EFTU PF00009.22 ETN97113.1 - 9.3e-05 21.9 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF3579 PF12112.3 ETN97113.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3579) MYCBPAP PF14646.1 ETN97113.1 - 0.5 9.0 3.5 1.7 7.2 2.7 1.5 1 1 1 2 2 2 0 MYCBP-associated protein family DUF755 PF05501.6 ETN97113.1 - 1.8 8.6 28.8 0.29 11.1 15.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DUF3446 PF11928.3 ETN97113.1 - 2.3 8.4 19.1 0.58 10.3 10.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3446) Mito_carr PF00153.22 ETN97115.1 - 0.00023 20.7 0.0 0.00055 19.6 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial carrier protein Pox_int_trans PF05718.7 ETN97115.1 - 0.059 11.8 0.0 0.081 11.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus intermediate transcription factor SecA_DEAD PF07517.9 ETN97116.1 - 0.002 17.4 0.4 0.044 13.0 0.0 3.0 2 2 0 2 2 2 1 SecA DEAD-like domain DUF1018 PF06252.7 ETN97116.1 - 0.0045 17.4 0.3 0.16 12.4 0.0 3.2 2 2 0 2 2 2 1 Protein of unknown function (DUF1018) ZZ PF00569.12 ETN97116.1 - 0.0082 15.6 1.2 0.018 14.5 0.8 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type UpxZ PF06603.6 ETN97116.1 - 0.055 13.4 2.8 0.36 10.8 0.0 3.3 4 0 0 4 4 4 0 UpxZ family of transcription anti-terminator antagonists PX PF00787.19 ETN97116.1 - 0.071 12.9 0.3 0.33 10.7 0.0 2.2 2 0 0 2 2 2 0 PX domain DUF2536 PF10750.4 ETN97116.1 - 0.18 11.4 4.3 0.074 12.6 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2536) DUF3783 PF12646.2 ETN97116.1 - 0.28 10.9 4.8 3.9 7.2 0.0 4.0 4 1 1 5 5 5 0 Domain of unknown function (DUF3783) PhoU PF01895.14 ETN97116.1 - 1.1 9.7 11.4 0.2 12.0 0.4 4.0 3 1 1 4 4 4 0 PhoU domain WD40 PF00400.27 ETN97117.1 - 1.9e-33 113.0 3.0 2.3e-13 49.4 0.1 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETN97117.1 - 3.8e-05 22.1 0.0 4.6e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome D1 heme domain eIF2A PF08662.6 ETN97117.1 - 8.8e-05 22.2 0.0 0.00018 21.2 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETN97117.1 - 0.0012 18.4 2.9 0.2 11.3 0.0 3.3 3 1 0 3 3 3 1 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.9 ETN97117.1 - 0.0029 16.4 0.1 0.0034 16.2 0.0 1.0 1 0 0 1 1 1 1 Coatomer WD associated region Tcp10_C PF07202.8 ETN97117.1 - 0.06 12.8 0.0 0.11 11.9 0.0 1.5 1 1 0 1 1 1 0 T-complex protein 10 C-terminus Proteasome_A_N PF10584.4 ETN97117.1 - 0.32 10.3 1.5 14 5.1 0.0 3.0 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature TFIIA PF03153.8 ETN97118.1 - 0.055 13.3 44.1 0.06 13.2 30.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4020 PF13212.1 ETN97119.1 - 0.11 12.0 0.5 0.13 11.8 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4020) NACHT PF05729.7 ETN97120.1 - 0.001 18.7 1.3 0.14 11.7 0.0 2.7 3 0 0 3 3 3 2 NACHT domain AAA_18 PF13238.1 ETN97120.1 - 0.0014 18.9 4.5 0.016 15.4 0.1 2.5 2 1 0 2 2 2 1 AAA domain FliG_M PF14841.1 ETN97120.1 - 0.017 15.1 0.2 4.6 7.3 0.0 2.3 2 0 0 2 2 2 0 FliG middle domain Zeta_toxin PF06414.7 ETN97120.1 - 0.026 13.6 0.0 0.35 9.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.1 ETN97120.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 ETN97120.1 - 0.41 10.5 6.5 2.8 7.8 0.2 2.4 1 1 1 2 2 2 0 AAA domain Peptidase_S9 PF00326.16 ETN97121.1 - 2.2e-34 118.5 0.1 2.8e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 ETN97121.1 - 0.0082 15.5 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase BAAT_C PF08840.6 ETN97121.1 - 0.025 14.2 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 ETN97121.1 - 0.095 12.2 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1675 PF07897.6 ETN97123.1 - 0.031 14.1 13.9 0.037 13.8 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Peptidase_S64 PF08192.6 ETN97123.1 - 0.086 11.1 10.5 0.092 11.0 7.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 TFIIA PF03153.8 ETN97123.1 - 2.4 7.9 14.7 2.8 7.7 10.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 ETN97123.1 - 6.8 4.8 13.3 7.8 4.6 9.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Actin PF00022.14 ETN97124.1 - 1.7e-12 46.5 0.0 1.8e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Actin Nro1 PF12753.2 ETN97127.1 - 0.011 14.6 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 TPR_2 PF07719.12 ETN97127.1 - 0.016 15.1 7.9 0.12 12.3 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETN97127.1 - 0.13 12.1 0.1 0.33 10.8 0.1 1.7 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.1 ETN97127.1 - 0.15 11.9 6.0 2.6 8.0 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETN97127.1 - 0.17 11.5 4.2 1.1 8.9 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETN97127.1 - 0.22 11.4 6.8 4.6 7.2 0.1 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.27 ETN97129.1 - 6.5e-21 73.3 0.3 2.6e-09 36.5 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETN97129.1 - 0.00011 20.5 0.1 0.18 9.9 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETN97129.1 - 0.046 12.4 1.5 2.8 6.6 0.0 2.5 1 1 2 3 3 3 0 Nup133 N terminal like Kelch_6 PF13964.1 ETN97130.1 - 0.27 11.4 1.4 11 6.4 0.1 2.8 3 0 0 3 3 3 0 Kelch motif TFR_dimer PF04253.10 ETN97131.1 - 0.02 14.4 1.9 0.035 13.6 1.3 1.5 1 1 0 1 1 1 0 Transferrin receptor-like dimerisation domain DASH_Dam1 PF08653.5 ETN97131.1 - 0.027 14.2 1.0 0.071 12.8 0.2 2.0 2 0 0 2 2 2 0 DASH complex subunit Dam1 Med9 PF07544.8 ETN97131.1 - 0.033 13.8 1.8 0.033 13.8 1.2 1.9 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Baculo_gp64 PF03273.8 ETN97131.1 - 0.049 11.7 3.5 0.052 11.7 2.4 1.0 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family DUF2803 PF10972.3 ETN97131.1 - 0.1 12.0 1.9 0.12 11.9 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2803) Nab2 PF11517.3 ETN97131.1 - 0.12 12.4 2.7 1.6 8.8 0.1 2.2 2 0 0 2 2 2 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) DUF1826 PF08856.6 ETN97131.1 - 0.15 11.8 1.2 0.17 11.6 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1826) DUF3138 PF11336.3 ETN97131.1 - 0.21 9.7 0.9 0.26 9.4 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) bZIP_2 PF07716.10 ETN97131.1 - 0.28 11.0 3.4 0.63 9.9 2.4 1.6 1 0 0 1 1 1 0 Basic region leucine zipper DUF3573 PF12097.3 ETN97131.1 - 0.36 9.4 6.7 0.38 9.3 4.5 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) IncA PF04156.9 ETN97131.1 - 0.56 9.7 8.9 0.93 9.0 6.2 1.5 1 1 0 1 1 1 0 IncA protein Seryl_tRNA_N PF02403.17 ETN97131.1 - 0.71 9.9 9.8 1.1 9.2 5.8 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4200 PF13863.1 ETN97131.1 - 1 9.3 12.5 0.16 11.9 6.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Bap31 PF05529.7 ETN97131.1 - 2.4 7.5 9.6 2.9 7.2 6.7 1.3 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like YmzC PF14157.1 ETN97132.1 - 0.2 11.4 3.2 0.21 11.4 1.4 1.7 1 1 0 1 1 1 0 YmzC-like protein DUF1387 PF07139.6 ETN97132.1 - 0.26 10.8 17.4 0.3 10.6 12.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DUF3395 PF11875.3 ETN97132.1 - 0.75 9.4 5.9 0.99 9.0 3.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3395) WD40 PF00400.27 ETN97134.1 - 1.2e-13 50.3 7.4 9.4e-11 41.1 2.2 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETN97134.1 - 5.9e-06 24.7 0.1 6e-06 24.6 0.1 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Herpes_teg_N PF04843.7 ETN97135.1 - 0.13 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region UPF0172 PF03665.8 ETN97135.1 - 3.9 6.9 5.4 0.71 9.3 1.3 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) COX5A PF02284.11 ETN97138.1 - 0.017 15.0 0.5 0.021 14.7 0.3 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va Syntaxin_2 PF14523.1 ETN97138.1 - 3.4 7.7 7.5 22 5.1 5.2 2.3 1 1 0 1 1 1 0 Syntaxin-like protein Sterile PF03015.14 ETN97138.1 - 5.2 7.3 7.3 0.72 10.1 0.5 2.1 1 1 0 2 2 2 0 Male sterility protein WD40 PF00400.27 ETN97140.1 - 1.4e-28 97.7 1.9 1.2e-13 50.3 0.1 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Pentapeptide_4 PF13599.1 ETN97140.1 - 0.00019 21.1 0.1 0.00049 19.8 0.1 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETN97140.1 - 0.00021 20.4 0.0 0.00051 19.2 0.0 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 ETN97140.1 - 0.0017 18.2 1.7 0.0064 16.3 1.2 2.0 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Proteasome_A_N PF10584.4 ETN97140.1 - 0.097 12.0 0.0 6.2 6.2 0.0 2.6 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature DUF607 PF04678.8 ETN97143.1 - 0.064 13.1 0.3 0.064 13.1 0.2 1.7 1 1 1 2 2 2 0 Protein of unknown function, DUF607 XPG_I_2 PF12813.2 ETN97143.1 - 0.57 9.6 3.2 0.8 9.1 2.2 1.1 1 0 0 1 1 1 0 XPG domain containing DUF3035 PF11233.3 ETN97143.1 - 0.6 10.1 2.1 0.81 9.7 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) TcdA_TcdB_pore PF12920.2 ETN97143.1 - 1.8 6.3 8.2 2.1 6.1 5.7 1.0 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain WD40 PF00400.27 ETN97144.1 - 1.7e-16 59.3 4.9 4.7e-10 38.9 0.1 3.6 3 1 0 3 3 3 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 ETN97144.1 - 0.034 13.9 0.1 0.1 12.3 0.1 1.8 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 ETN97144.1 - 0.055 11.5 0.2 0.34 8.9 0.0 1.9 1 1 0 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETN97144.1 - 0.11 11.2 0.2 0.31 9.7 0.1 1.8 1 1 0 1 1 1 0 Nup133 N terminal like Kdo PF06293.9 ETN97146.1 - 0.00096 18.2 0.1 0.0018 17.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Multi-haem_cyto PF13447.1 ETN97146.1 - 0.032 13.2 0.8 0.048 12.7 0.4 1.3 1 1 0 1 1 1 0 Seven times multi-haem cytochrome CxxCH RNase_H PF00075.19 ETN97148.1 - 2.1e-05 24.8 1.0 0.096 13.0 0.0 2.6 2 1 1 3 3 3 2 RNase H DUF3702 PF12486.3 ETN97148.1 - 0.0016 18.0 0.2 0.0024 17.5 0.1 1.3 1 0 0 1 1 1 1 ImpA domain protein DUF2262 PF10020.4 ETN97148.1 - 0.0019 18.3 1.5 0.013 15.7 0.8 2.2 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2262) RVT_3 PF13456.1 ETN97148.1 - 0.026 14.2 0.6 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 Reverse transcriptase-like UPF0546 PF10639.4 ETN97148.1 - 0.15 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0546 BLOC1_2 PF10046.4 ETN97149.1 - 0.0083 16.2 6.1 0.015 15.3 4.3 1.4 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 PRESAN PF09687.5 ETN97149.1 - 0.017 15.1 4.2 0.05 13.6 2.9 1.9 1 1 1 2 2 2 0 Plasmodium RESA N-terminal DUF1672 PF07901.6 ETN97149.1 - 0.017 14.0 1.9 0.027 13.4 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) TMF_TATA_bd PF12325.3 ETN97149.1 - 0.021 14.5 1.9 0.037 13.7 1.3 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 ETN97149.1 - 0.024 14.2 2.4 0.035 13.6 1.6 1.2 1 0 0 1 1 1 0 IncA protein DUF2452 PF10504.4 ETN97149.1 - 0.12 11.6 0.7 0.21 10.8 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) YlbD_coat PF14071.1 ETN97149.1 - 0.18 11.8 1.5 0.36 10.8 1.0 1.5 1 0 0 1 1 1 0 Putative coat protein DUF16 PF01519.11 ETN97149.1 - 0.18 12.0 3.2 0.11 12.7 1.0 1.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 Tubulin PF00091.20 ETN97151.1 - 9.6e-25 87.6 1.4 1.8e-13 50.7 0.3 3.0 1 1 1 2 2 2 2 Tubulin/FtsZ family, GTPase domain KSR1-SAM PF13543.1 ETN97154.1 - 5.6e-06 26.1 3.8 0.028 14.2 0.1 3.0 2 1 1 3 3 3 2 SAM like domain present in kinase suppressor RAS 1 DIL PF01843.14 ETN97154.1 - 0.00011 22.0 3.5 0.83 9.5 0.0 3.3 3 0 0 3 3 3 2 DIL domain HHH_5 PF14520.1 ETN97154.1 - 0.011 15.9 0.0 1.5 9.0 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix domain SAM_1 PF00536.25 ETN97154.1 - 0.013 15.6 0.1 0.56 10.4 0.0 2.6 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) HhH-GPD PF00730.20 ETN97154.1 - 0.03 14.6 0.1 1.3 9.2 0.0 2.8 2 1 0 3 3 3 0 HhH-GPD superfamily base excision DNA repair protein Slx4 PF09494.5 ETN97154.1 - 0.035 13.8 5.3 4.2 7.1 0.1 3.6 3 0 0 3 3 3 0 Slx4 endonuclease DUF148 PF02520.12 ETN97154.1 - 0.14 11.9 6.6 1.7 8.4 0.7 3.5 2 2 0 2 2 2 0 Domain of unknown function DUF148 Atx10homo_assoc PF09759.4 ETN97154.1 - 8.9 6.1 8.8 11 5.8 1.1 3.6 2 1 1 3 3 3 0 Spinocerebellar ataxia type 10 protein domain AIG1 PF04548.11 ETN97155.1 - 1.6e-10 40.4 0.6 1.6e-10 40.4 0.4 2.3 2 1 0 2 2 2 1 AIG1 family Septin PF00735.13 ETN97155.1 - 6.2e-10 38.5 0.1 1.3e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 ETN97155.1 - 1.3e-09 38.0 0.1 1.7e-08 34.3 0.0 2.6 2 1 1 3 3 3 1 50S ribosome-binding GTPase AAA_23 PF13476.1 ETN97155.1 - 1.5e-06 28.6 2.1 0.00016 22.0 1.4 2.5 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 ETN97155.1 - 1.9e-06 27.1 0.0 5.9e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 T2SE PF00437.15 ETN97155.1 - 5.5e-06 25.4 0.3 1.4e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein Dynamin_N PF00350.18 ETN97155.1 - 3e-05 23.8 4.8 0.08 12.7 0.0 3.4 3 1 0 4 4 3 2 Dynamin family Miro PF08477.8 ETN97155.1 - 0.00012 22.5 1.6 0.0013 19.2 0.1 3.1 2 1 0 2 2 2 1 Miro-like protein MobB PF03205.9 ETN97155.1 - 0.00022 20.9 0.2 0.00071 19.2 0.0 2.0 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 ETN97155.1 - 0.00056 20.2 0.1 0.0043 17.3 0.0 2.2 2 0 0 2 2 2 1 ABC transporter NACHT PF05729.7 ETN97155.1 - 0.00062 19.4 0.2 0.0021 17.7 0.0 2.0 2 0 0 2 2 2 1 NACHT domain GTP_EFTU PF00009.22 ETN97155.1 - 0.00097 18.6 0.0 0.0027 17.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 ETN97155.1 - 0.0024 18.0 0.5 0.0087 16.2 0.0 2.2 3 0 0 3 3 2 1 AAA domain ResIII PF04851.10 ETN97155.1 - 0.0027 17.5 1.7 0.041 13.7 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_28 PF13521.1 ETN97155.1 - 0.0039 17.1 0.1 0.94 9.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 ETN97155.1 - 0.0053 16.2 0.1 0.027 13.9 0.0 2.0 2 1 0 2 2 2 1 AAA-like domain AAA_29 PF13555.1 ETN97155.1 - 0.0056 16.1 0.0 0.016 14.7 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain PHD PF00628.24 ETN97155.1 - 0.0056 16.3 0.8 0.012 15.2 0.6 1.4 1 0 0 1 1 1 1 PHD-finger SRP54 PF00448.17 ETN97155.1 - 0.0067 15.8 1.6 0.21 11.0 0.0 2.9 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain TrwB_AAD_bind PF10412.4 ETN97155.1 - 0.0089 14.6 0.0 0.015 13.9 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.13 ETN97155.1 - 0.0096 15.4 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family PduV-EutP PF10662.4 ETN97155.1 - 0.011 15.2 0.0 0.031 13.7 0.0 1.8 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 ETN97155.1 - 0.014 15.0 1.3 0.12 12.0 0.0 2.6 2 1 1 3 3 3 0 Archaeal ATPase FeoB_N PF02421.13 ETN97155.1 - 0.014 14.6 0.1 1.3 8.2 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B HECT PF00632.20 ETN97155.1 - 0.017 14.2 0.8 0.031 13.4 0.6 1.4 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) AAA_30 PF13604.1 ETN97155.1 - 0.018 14.5 0.0 0.052 13.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.1 ETN97155.1 - 0.021 14.4 0.1 0.3 10.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 ETN97155.1 - 0.029 13.6 0.3 0.084 12.0 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_18 PF13238.1 ETN97155.1 - 0.03 14.6 0.4 0.14 12.4 0.1 2.3 2 1 0 2 2 1 0 AAA domain cobW PF02492.14 ETN97155.1 - 0.032 13.6 0.4 0.14 11.5 0.1 2.2 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 ETN97155.1 - 0.034 14.1 0.1 0.12 12.3 0.0 1.9 2 0 0 2 2 1 0 AAA ATPase domain AAA_17 PF13207.1 ETN97155.1 - 0.036 14.8 0.0 0.72 10.6 0.0 2.8 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 ETN97155.1 - 0.053 13.0 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain PspA_IM30 PF04012.7 ETN97155.1 - 0.065 12.5 3.2 0.12 11.7 2.2 1.3 1 0 0 1 1 1 0 PspA/IM30 family AAA_19 PF13245.1 ETN97155.1 - 0.07 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain ATP_bind_1 PF03029.12 ETN97155.1 - 0.071 12.6 0.2 0.99 8.8 0.0 2.7 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein DUF87 PF01935.12 ETN97155.1 - 0.12 12.1 4.6 1.3 8.8 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function DUF87 Laminin_II PF06009.7 ETN97156.1 - 0.0014 18.3 12.7 0.0014 18.3 8.8 3.0 1 1 2 3 3 3 1 Laminin Domain II HAUS-augmin3 PF14932.1 ETN97156.1 - 0.004 16.3 20.5 0.004 16.3 14.2 2.1 1 1 1 2 2 2 1 HAUS augmin-like complex subunit 3 Reo_sigmaC PF04582.7 ETN97156.1 - 0.0045 16.2 2.9 0.0045 16.2 2.0 2.4 1 1 2 3 3 3 3 Reovirus sigma C capsid protein Fib_alpha PF08702.5 ETN97156.1 - 0.18 11.9 48.1 0.54 10.3 13.6 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CALCOCO1 PF07888.6 ETN97156.1 - 0.89 7.7 41.5 1.1 7.4 28.8 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF972 PF06156.8 ETN97156.1 - 3.6 7.9 51.5 2.8 8.3 5.2 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF972) bZIP_1 PF00170.16 ETN97156.1 - 7.7 6.5 55.5 0.17 11.8 4.0 5.8 3 3 2 5 5 5 0 bZIP transcription factor APG6 PF04111.7 ETN97156.1 - 7.8 5.4 60.9 1.2 8.1 19.0 2.7 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF3450 PF11932.3 ETN97156.1 - 7.8 5.6 47.7 0.1 11.8 11.9 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) FliD_C PF07195.7 ETN97156.1 - 8.3 5.6 34.1 0.077 12.2 11.6 2.2 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus CCDC155 PF14662.1 ETN97156.1 - 9.1 5.8 59.1 0.66 9.5 5.0 3.1 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 RVT_3 PF13456.1 ETN97156.1 - 9.5 6.0 9.4 2.3 8.0 0.5 3.2 2 1 2 4 4 4 0 Reverse transcriptase-like ACP53EA PF06313.6 ETN97157.1 - 0.018 14.9 0.5 0.044 13.7 0.3 1.7 1 1 1 2 2 2 0 Drosophila ACP53EA protein SidE PF12252.3 ETN97157.1 - 0.034 11.4 3.1 0.038 11.3 2.2 1.0 1 0 0 1 1 1 0 Dot/Icm substrate protein Flu_NS2 PF00601.14 ETN97157.1 - 0.057 13.6 1.7 0.092 12.9 1.2 1.3 1 0 0 1 1 1 0 Influenza non-structural protein (NS2) DUF641 PF04859.7 ETN97157.1 - 0.068 12.9 0.5 0.091 12.5 0.4 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF4200 PF13863.1 ETN97157.1 - 0.073 13.0 1.1 0.1 12.5 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) IncA PF04156.9 ETN97157.1 - 0.1 12.2 0.8 0.13 11.8 0.5 1.1 1 0 0 1 1 1 0 IncA protein LRR_3 PF07725.7 ETN97158.1 - 0.13 12.0 0.1 0.28 11.0 0.1 1.6 1 0 0 1 1 1 0 Leucine Rich Repeat UBN2 PF14223.1 ETN97159.1 - 0.02 14.6 0.5 0.02 14.6 0.3 3.0 2 1 0 2 2 2 0 gag-polypeptide of LTR copia-type DUF2450 PF10475.4 ETN97159.1 - 0.032 13.1 0.4 0.032 13.1 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function N-terminal domain (DUF2450) Laminin_II PF06009.7 ETN97159.1 - 0.16 11.7 25.0 0.21 11.3 3.5 3.1 2 1 1 3 3 3 0 Laminin Domain II adh_short PF00106.20 ETN97159.1 - 0.25 11.2 1.6 0.38 10.6 1.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Lzipper-MIP1 PF14389.1 ETN97159.1 - 0.9 9.6 14.1 1.4 9.0 0.5 2.5 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF16 PF01519.11 ETN97159.1 - 1.1 9.5 15.1 0.75 10.0 2.5 3.0 1 1 0 2 2 2 0 Protein of unknown function DUF16 AAA_23 PF13476.1 ETN97159.1 - 1.2 9.4 16.0 1.4e+03 -0.6 11.1 2.2 1 1 0 1 1 1 0 AAA domain AF0941-like PF14591.1 ETN97159.1 - 2.5 8.1 14.2 0.055 13.5 1.9 3.0 2 1 1 3 3 3 0 AF0941-like DUF3552 PF12072.3 ETN97159.1 - 3.6 6.7 32.2 2.5 7.2 6.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3552) COG2 PF06148.6 ETN97159.1 - 4.2 7.2 14.9 0.28 11.0 1.1 3.4 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 LAM_C PF12544.3 ETN97159.1 - 5.3 7.1 5.6 2.4 8.2 0.0 2.5 2 1 1 3 3 3 0 Lysine-2,3-aminomutase DUF4455 PF14643.1 ETN97160.1 - 0.023 13.3 12.9 0.029 13.0 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) DUF885 PF05960.6 ETN97160.1 - 0.027 13.6 2.6 0.027 13.6 1.8 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) DASH_Dam1 PF08653.5 ETN97160.1 - 0.047 13.4 1.6 0.067 12.9 0.1 2.0 2 1 0 2 2 2 0 DASH complex subunit Dam1 G-alpha PF00503.15 ETN97160.1 - 0.084 11.5 5.3 0.094 11.3 3.7 1.1 1 0 0 1 1 1 0 G-protein alpha subunit AdoMet_Synthase PF01941.14 ETN97160.1 - 0.12 10.8 2.8 0.13 10.7 1.3 1.5 1 1 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) Zein PF01559.11 ETN97160.1 - 0.15 11.2 5.5 0.23 10.6 3.8 1.4 1 1 0 1 1 1 0 Zein seed storage protein Imm45 PF15603.1 ETN97160.1 - 0.37 10.9 4.4 14 5.8 1.1 2.4 1 1 1 2 2 2 0 Immunity protein 45 Fib_alpha PF08702.5 ETN97160.1 - 0.63 10.1 17.5 1.8 8.7 12.1 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family LMBR1 PF04791.11 ETN97160.1 - 0.75 8.3 4.3 0.9 8.0 3.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DIT1_PvcA PF05141.7 ETN97160.1 - 0.92 8.7 5.9 1.1 8.4 4.1 1.1 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein Nop16 PF09420.5 ETN97160.1 - 1 9.4 7.3 1.4 8.9 5.0 1.1 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 FANCI_S2 PF14676.1 ETN97160.1 - 1.4 8.7 6.5 5.5 6.8 4.5 1.9 1 1 0 1 1 1 0 FANCI solenoid 2 DUF745 PF05335.8 ETN97160.1 - 2 7.9 9.5 0.76 9.2 3.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF148 PF02520.12 ETN97160.1 - 2.1 8.1 14.8 5.6 6.7 2.6 2.3 1 1 1 2 2 2 0 Domain of unknown function DUF148 Lge1 PF11488.3 ETN97160.1 - 2.4 8.4 6.8 0.31 11.2 0.7 2.1 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 Cob_adeno_trans PF01923.13 ETN97160.1 - 6.2 6.5 6.7 7.7 6.2 3.2 1.9 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Rap_GAP PF02145.10 ETN97162.1 - 0.013 14.8 0.4 0.016 14.6 0.3 1.2 1 0 0 1 1 1 0 Rap/ran-GAP SecA_DEAD PF07517.9 ETN97163.1 - 3.8e-10 39.5 0.0 9.8e-10 38.1 0.0 1.6 1 0 0 1 1 1 1 SecA DEAD-like domain VWA_2 PF13519.1 ETN97163.1 - 1.3e-09 38.4 0.0 2.3e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Helicase_C PF00271.26 ETN97163.1 - 0.00017 21.3 0.0 0.00065 19.5 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF563 PF04577.9 ETN97164.1 - 0.0035 17.2 0.1 0.0038 17.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF1636 PF07845.6 ETN97165.1 - 0.14 12.3 0.7 0.22 11.7 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1636) ASL_C PF08328.6 ETN97165.1 - 0.15 11.8 9.0 0.095 12.5 4.5 1.7 1 1 1 2 2 2 0 Adenylosuccinate lyase C-terminal DUF2911 PF11138.3 ETN97165.1 - 0.58 9.7 6.1 0.17 11.4 2.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2911) Cyc-maltodext_C PF10438.4 ETN97165.1 - 9 6.4 13.0 18 5.4 0.9 3.3 2 1 1 3 3 3 0 Cyclo-malto-dextrinase C-terminal domain TH1 PF04858.8 ETN97167.1 - 0.00059 18.1 6.9 0.0015 16.7 0.3 2.9 2 1 1 3 3 3 2 TH1 protein Kelch_4 PF13418.1 ETN97171.1 - 1.5e-06 27.8 0.0 0.0047 16.6 0.0 2.4 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETN97171.1 - 1.7e-06 27.5 0.1 0.0045 16.7 0.1 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.1 ETN97171.1 - 3.9e-06 26.7 0.1 0.0026 17.8 0.2 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.20 ETN97171.1 - 0.00022 20.7 0.3 0.0035 16.8 0.1 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETN97171.1 - 0.00086 19.4 0.0 0.0086 16.2 0.0 2.4 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETN97171.1 - 0.075 13.0 0.3 0.25 11.3 0.2 1.8 2 0 0 2 2 2 0 Kelch motif ATP-synt_10 PF05176.9 ETN97172.1 - 0.99 8.6 11.4 1 8.5 7.2 1.6 1 1 0 1 1 1 0 ATP10 protein Sec20 PF03908.8 ETN97172.1 - 3.7 7.3 12.2 0.74 9.5 0.5 3.2 1 1 2 3 3 3 0 Sec20 IFT57 PF10498.4 ETN97173.1 - 0.0055 15.4 11.0 0.012 14.3 7.5 1.7 1 1 0 1 1 1 1 Intra-flagellar transport protein 57 Reo_sigmaC PF04582.7 ETN97173.1 - 0.024 13.8 3.3 0.054 12.6 2.3 1.6 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Penicil_amidase PF01804.13 ETN97173.1 - 0.037 13.0 2.2 0.054 12.5 1.5 1.2 1 0 0 1 1 1 0 Penicillin amidase DUF3452 PF11934.3 ETN97173.1 - 0.051 12.8 1.5 0.11 11.8 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) DUF1664 PF07889.7 ETN97173.1 - 0.081 12.7 17.3 0.085 12.6 5.2 3.3 4 0 0 4 4 3 0 Protein of unknown function (DUF1664) DSX_dimer PF08828.5 ETN97173.1 - 0.2 11.2 1.5 0.51 9.9 1.0 1.7 1 0 0 1 1 1 0 Doublesex dimerisation domain Bacillus_HBL PF05791.6 ETN97173.1 - 0.2 11.0 9.7 0.069 12.5 3.4 2.7 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) ING PF12998.2 ETN97173.1 - 0.2 11.9 8.9 0.46 10.7 0.9 2.7 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Lectin_N PF03954.9 ETN97173.1 - 0.2 11.0 2.0 0.35 10.2 0.7 1.9 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain IncA PF04156.9 ETN97173.1 - 0.25 10.9 11.7 0.15 11.6 5.7 2.3 2 1 1 3 3 2 0 IncA protein AAA_13 PF13166.1 ETN97173.1 - 0.3 9.4 17.5 0.62 8.4 12.2 1.5 1 0 0 1 1 1 0 AAA domain 5_nucleotid PF05761.9 ETN97173.1 - 0.41 9.1 5.7 1.3 7.5 3.9 1.9 1 1 0 1 1 1 0 5' nucleotidase family DUF4140 PF13600.1 ETN97173.1 - 0.42 11.0 11.2 0.8 10.1 3.8 3.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) V_ATPase_I PF01496.14 ETN97173.1 - 0.57 7.9 9.4 0.91 7.2 6.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4200 PF13863.1 ETN97173.1 - 0.66 9.9 19.8 1.4 8.8 9.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) COG2 PF06148.6 ETN97173.1 - 0.72 9.7 10.2 2.7 7.8 5.4 3.3 3 2 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.7 ETN97173.1 - 1.5 8.6 10.1 2.2 8.0 4.2 3.1 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Vps53_N PF04100.7 ETN97173.1 - 1.6 7.4 12.9 1.8 7.2 7.1 2.4 3 1 0 3 3 3 0 Vps53-like, N-terminal Atg14 PF10186.4 ETN97173.1 - 1.8 7.4 10.2 3.1 6.6 7.1 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Tim44 PF04280.10 ETN97173.1 - 1.8 8.4 11.4 0.59 10.1 2.7 2.7 2 1 1 3 3 3 0 Tim44-like domain CENP-Q PF13094.1 ETN97173.1 - 2 8.4 13.3 2.3 8.2 8.1 2.0 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Seryl_tRNA_N PF02403.17 ETN97173.1 - 2 8.4 22.8 2.7 8.0 9.6 3.4 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Flagellin_C PF00700.16 ETN97173.1 - 2.1 8.5 5.9 3 8.0 0.9 2.9 2 1 1 3 3 2 0 Bacterial flagellin C-terminal helical region Nup54 PF13874.1 ETN97173.1 - 3 7.5 8.0 3.8 7.1 3.6 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 ISG65-75 PF11727.3 ETN97173.1 - 4.1 6.3 23.5 0.2 10.7 10.2 2.5 2 1 1 3 3 3 0 Invariant surface glycoprotein DUF948 PF06103.6 ETN97173.1 - 4.8 7.0 9.1 9.6 6.1 3.9 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Cytochrom_B562 PF07361.6 ETN97173.1 - 6.1 7.3 24.8 5.9 7.3 5.7 3.8 2 2 1 3 3 3 0 Cytochrome b562 Prefoldin_2 PF01920.15 ETN97173.1 - 7.8 6.3 19.2 1.7 8.4 3.7 3.7 1 1 2 3 3 3 0 Prefoldin subunit FAM217 PF15344.1 ETN97176.1 - 0.01 15.3 3.2 0.01 15.3 2.2 1.6 1 1 0 2 2 2 0 FAM217 family RNA_pol_Rpb5_C PF01191.14 ETN97176.1 - 0.023 14.2 1.8 0.026 14.1 0.5 1.6 2 0 0 2 2 2 0 RNA polymerase Rpb5, C-terminal domain TPR_12 PF13424.1 ETN97177.1 - 4.2e-30 103.4 9.2 6.7e-19 67.6 1.7 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETN97177.1 - 3.2e-15 55.5 11.9 2.8e-09 36.5 3.2 2.2 1 1 1 2 2 2 2 TPR repeat TPR_7 PF13176.1 ETN97177.1 - 2e-12 45.8 3.5 0.00034 20.2 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETN97177.1 - 3e-12 45.5 12.8 3.6e-06 26.3 1.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETN97177.1 - 3.4e-11 42.6 0.0 0.00037 20.3 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETN97177.1 - 3.5e-09 35.8 9.5 0.0061 16.3 0.4 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETN97177.1 - 8.4e-07 28.3 10.7 0.014 15.1 0.6 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETN97177.1 - 0.00012 21.9 1.2 3.6 8.0 0.0 3.7 3 2 0 3 3 3 1 Tetratricopeptide repeat SNAP PF14938.1 ETN97177.1 - 0.0014 17.8 0.3 0.0018 17.4 0.2 1.2 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_14 PF13428.1 ETN97177.1 - 0.0076 16.8 0.0 3.2 8.6 0.0 2.5 3 0 0 3 3 2 1 Tetratricopeptide repeat DUF3568 PF12092.3 ETN97177.1 - 0.041 13.5 0.0 0.27 10.9 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3568) TPR_16 PF13432.1 ETN97177.1 - 0.056 14.1 0.5 0.75 10.5 0.7 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat Inhibitor_I9 PF05922.11 ETN97177.1 - 0.078 13.5 0.3 0.13 12.7 0.2 1.4 1 0 0 1 1 1 0 Peptidase inhibitor I9 Ten1_2 PF15490.1 ETN97177.1 - 0.091 12.3 0.1 4.2 6.9 0.0 2.1 1 1 1 2 2 2 0 Telomere-capping, CST complex subunit TPR_19 PF14559.1 ETN97177.1 - 0.13 12.5 0.8 1.2 9.5 0.3 2.3 1 1 2 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETN97177.1 - 0.2 11.5 3.9 0.5 10.2 0.1 2.3 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 ETN97177.1 - 0.23 11.3 8.0 2.9 7.8 1.2 2.2 1 1 1 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 ETN97177.1 - 0.26 11.1 6.2 2.4 8.0 0.4 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 ETN97177.1 - 0.69 10.0 5.2 1.6 8.8 3.3 1.9 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 ETN97177.1 - 1.9 8.6 5.7 4.3 7.5 0.1 3.3 4 0 0 4 4 3 0 PPR repeat AAA PF00004.24 ETN97178.1 - 6.2e-08 32.9 0.0 0.00015 21.9 0.0 3.2 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETN97178.1 - 8.2e-07 28.8 0.0 0.0011 18.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETN97178.1 - 1.8e-06 28.0 0.1 0.017 15.2 0.0 3.5 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 ETN97178.1 - 0.00042 19.5 0.0 0.0014 17.7 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 ETN97178.1 - 0.00046 20.4 0.4 0.0033 17.7 0.1 2.6 2 1 0 2 2 2 1 ABC transporter AAA_16 PF13191.1 ETN97178.1 - 0.0018 18.3 0.0 0.63 9.9 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 ETN97178.1 - 0.0019 17.2 0.0 0.0057 15.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 ETN97178.1 - 0.0026 17.6 1.4 0.019 14.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.1 ETN97178.1 - 0.004 17.1 0.1 0.16 12.0 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain MCM PF00493.18 ETN97178.1 - 0.0068 15.2 0.9 0.087 11.6 0.0 2.7 3 0 0 3 3 3 1 MCM2/3/5 family T2SE PF00437.15 ETN97178.1 - 0.013 14.3 0.0 2.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein PduV-EutP PF10662.4 ETN97178.1 - 0.015 14.7 0.5 0.062 12.7 0.1 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 ETN97178.1 - 0.019 14.6 2.1 1.2 8.7 0.1 3.2 3 0 0 3 3 3 0 NACHT domain Sigma54_activat PF00158.21 ETN97178.1 - 0.021 14.2 0.0 0.62 9.5 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain RNA_helicase PF00910.17 ETN97178.1 - 0.048 13.8 0.3 1.8 8.7 0.1 3.2 2 1 0 2 2 2 0 RNA helicase AAA_19 PF13245.1 ETN97178.1 - 0.074 12.8 0.1 7.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain Mg_chelatase PF01078.16 ETN97178.1 - 0.077 12.1 0.1 10 5.2 0.0 2.6 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI UPF0079 PF02367.12 ETN97178.1 - 0.24 11.0 2.5 0.44 10.1 0.0 2.5 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 PI3_PI4_kinase PF00454.22 ETN97180.1 - 1e-23 84.0 0.6 1.4e-23 83.6 0.4 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 ETN97180.1 - 2.4e-13 49.2 0.1 4.7e-13 48.3 0.1 1.5 1 0 0 1 1 1 1 FATC domain PAS_6 PF08348.6 ETN97180.1 - 0.013 15.0 2.3 0.066 12.7 0.0 2.7 3 1 1 4 4 4 0 YheO-like PAS domain Chordopox_A35R PF05989.7 ETN97180.1 - 0.018 14.6 1.9 0.04 13.5 1.3 1.5 1 1 0 1 1 1 0 Chordopoxvirus A35R protein CHAT PF12770.2 ETN97181.1 - 5.1e-08 32.3 0.1 9.9e-08 31.4 0.1 1.4 1 0 0 1 1 1 1 CHAT domain Mei5 PF10376.4 ETN97183.1 - 0.0012 18.4 5.1 0.0014 18.1 3.6 1.1 1 0 0 1 1 1 1 Double-strand recombination repair protein DUF4160 PF13711.1 ETN97183.1 - 0.15 11.9 0.3 0.23 11.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4160) ATHILA PF03078.10 ETN97183.1 - 0.68 8.4 4.9 0.77 8.2 3.4 1.1 1 0 0 1 1 1 0 ATHILA ORF-1 family Microvir_H PF04687.7 ETN97184.1 - 0.082 11.9 4.2 0.084 11.8 2.9 1.0 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) Phi-29_GP16_7 PF06720.6 ETN97184.1 - 0.12 12.0 1.2 0.13 11.9 0.9 1.1 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 PspB PF06667.7 ETN97184.1 - 0.12 12.3 0.7 0.15 12.0 0.5 1.2 1 0 0 1 1 1 0 Phage shock protein B STAT_alpha PF01017.15 ETN97184.1 - 0.14 11.9 4.8 0.14 11.8 3.3 1.0 1 0 0 1 1 1 0 STAT protein, all-alpha domain TMF_DNA_bd PF12329.3 ETN97184.1 - 0.17 11.7 6.6 0.23 11.2 4.6 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Spore_GerAC PF05504.6 ETN97184.1 - 1 9.1 8.2 1 9.0 5.7 1.0 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal IncA PF04156.9 ETN97184.1 - 2.9 7.4 6.6 2.9 7.4 4.6 1.0 1 0 0 1 1 1 0 IncA protein Elf1 PF05129.8 ETN97185.1 - 0.0033 17.0 0.1 0.0069 16.0 0.1 1.6 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like DUF4058 PF13267.1 ETN97185.1 - 0.41 9.7 3.1 0.55 9.3 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4058) CAML PF14963.1 ETN97185.1 - 2.1 7.6 5.8 2.8 7.2 4.0 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Secretin_N_2 PF07655.8 ETN97186.1 - 2.9 8.3 8.8 0.46 10.9 2.9 2.0 2 0 0 2 2 2 0 Secretin N-terminal domain UPF0158 PF03682.8 ETN97187.1 - 0.013 15.1 0.1 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) TPR_12 PF13424.1 ETN97188.1 - 6.5e-55 182.9 19.3 2.3e-24 85.1 1.5 2.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETN97188.1 - 1.9e-26 90.5 25.3 1.8e-11 43.1 1.3 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETN97188.1 - 2.9e-26 90.5 1.3 1.1e-09 37.9 0.0 3.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETN97188.1 - 8e-26 89.4 27.3 7.4e-11 41.5 3.5 3.7 2 2 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 ETN97188.1 - 2.4e-21 73.8 17.7 5e-09 35.3 0.4 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETN97188.1 - 4e-20 69.9 5.1 4.5e-08 32.3 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETN97188.1 - 1.6e-16 58.7 25.1 1.9e-08 33.4 0.8 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETN97188.1 - 2.5e-13 50.3 3.4 2.4e-07 31.2 0.0 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETN97188.1 - 1.6e-12 46.5 10.8 0.0005 20.0 0.1 4.4 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETN97188.1 - 7e-10 38.6 0.0 0.0098 16.4 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETN97188.1 - 2.1e-09 37.2 4.6 0.016 15.6 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETN97188.1 - 5.7e-09 35.0 0.4 0.014 14.6 0.0 3.4 3 0 0 3 3 3 3 SHNi-TPR Apc3 PF12895.2 ETN97188.1 - 1.4e-07 31.4 10.5 0.0006 19.8 1.0 2.8 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETN97188.1 - 7.1e-07 29.4 1.9 0.037 14.3 0.3 2.5 1 1 2 3 3 3 3 Tetratricopeptide repeat DUF627 PF04781.7 ETN97188.1 - 4.1e-06 26.3 1.7 0.058 13.0 0.0 3.1 1 1 2 3 3 3 2 Protein of unknown function (DUF627) TPR_5 PF12688.2 ETN97188.1 - 7.8e-05 22.6 0.1 0.027 14.5 0.0 2.2 1 1 1 2 2 2 2 Tetratrico peptide repeat TPR_3 PF07720.7 ETN97188.1 - 8.5e-05 22.2 14.0 0.009 15.7 0.5 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat SNAP PF14938.1 ETN97188.1 - 8.6e-05 21.8 7.5 0.0043 16.2 1.5 2.6 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP DUF2225 PF09986.4 ETN97188.1 - 0.0064 15.9 5.6 0.054 12.9 0.5 2.4 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) ATP-synt_E_2 PF08112.6 ETN97188.1 - 0.012 15.6 1.1 10 6.3 0.0 3.2 3 0 0 3 3 3 0 ATP synthase epsilon subunit MIT PF04212.13 ETN97188.1 - 0.016 15.0 15.0 0.022 14.6 0.5 3.8 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain PPR PF01535.15 ETN97188.1 - 0.031 14.2 0.8 37 4.5 0.1 3.3 3 0 0 3 3 3 0 PPR repeat OEP PF02321.13 ETN97188.1 - 0.073 12.6 2.9 0.54 9.8 0.4 2.3 2 1 0 2 2 2 0 Outer membrane efflux protein RTP PF02334.11 ETN97188.1 - 0.18 11.7 1.8 3.5 7.5 0.1 2.8 1 1 1 3 3 3 0 Replication terminator protein Fib_alpha PF08702.5 ETN97188.1 - 0.23 11.5 2.2 0.37 10.8 1.2 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Sel1 PF08238.7 ETN97188.1 - 0.23 12.1 5.0 1.4 9.6 0.0 3.7 4 0 0 4 4 4 0 Sel1 repeat RPN7 PF10602.4 ETN97188.1 - 0.33 10.3 4.2 1.4 8.2 2.8 2.3 1 1 0 1 1 1 0 26S proteasome subunit RPN7 NSF PF02071.15 ETN97188.1 - 0.84 10.4 7.7 9.6 7.2 0.0 4.3 4 0 0 4 4 4 0 Aromatic-di-Alanine (AdAR) repeat DUF1515 PF07439.6 ETN97189.1 - 0.00027 20.6 2.3 0.00027 20.6 1.6 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1515) DUF972 PF06156.8 ETN97189.1 - 0.033 14.5 13.1 0.13 12.5 3.6 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF972) Trans_reg_C PF00486.23 ETN97189.1 - 0.08 12.8 0.9 0.16 11.9 0.1 1.9 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal IncA PF04156.9 ETN97189.1 - 0.28 10.7 11.2 0.29 10.7 6.8 1.7 1 1 1 2 2 2 0 IncA protein TPR_MLP1_2 PF07926.7 ETN97189.1 - 2 8.1 15.1 2.4 7.9 4.4 3.4 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein IBN_N PF03810.14 ETN97190.1 - 1.9e-05 24.4 0.0 3.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Importin-beta N-terminal domain Kinetochor_Ybp2 PF08568.5 ETN97190.1 - 0.011 14.0 0.0 0.014 13.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin DUF1546 PF07571.8 ETN97190.1 - 0.029 14.4 0.2 0.12 12.4 0.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1546) HEAT_2 PF13646.1 ETN97190.1 - 0.072 13.3 0.1 0.4 10.9 0.1 1.9 1 1 0 1 1 1 0 HEAT repeats HEAT PF02985.17 ETN97190.1 - 0.15 12.1 0.6 0.93 9.7 0.0 2.5 2 0 0 2 2 2 0 HEAT repeat HEAT PF02985.17 ETN97191.1 - 1.3e-05 24.8 4.9 0.028 14.4 0.1 3.6 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 ETN97191.1 - 0.00086 19.5 2.5 0.0085 16.3 1.6 2.2 1 1 0 1 1 1 1 HEAT repeats Vac14_Fab1_bd PF12755.2 ETN97191.1 - 0.0015 18.8 0.2 0.042 14.2 0.0 2.6 1 1 0 2 2 2 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 ETN97191.1 - 0.0023 16.3 2.3 0.012 13.9 1.5 2.1 1 1 0 1 1 1 1 Adaptin N terminal region MMS19_C PF12460.3 ETN97191.1 - 0.0025 16.6 0.0 0.0025 16.6 0.0 2.3 2 1 1 3 3 3 2 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.1 ETN97191.1 - 0.0038 17.6 2.0 2 9.0 0.4 3.6 1 1 3 4 4 4 2 HEAT-like repeat Cohesin_HEAT PF12765.2 ETN97191.1 - 0.0052 16.7 0.4 0.011 15.6 0.2 1.6 1 0 0 1 1 1 1 HEAT repeat associated with sister chromatid cohesion Xpo1 PF08389.7 ETN97191.1 - 0.0088 15.9 1.1 0.047 13.5 0.6 2.3 1 1 1 2 2 2 1 Exportin 1-like protein Cnd3 PF12719.2 ETN97191.1 - 0.021 13.8 0.4 0.032 13.2 0.3 1.4 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain HEAT PF02985.17 ETN97192.1 - 0.00046 20.0 0.4 3.1 8.1 0.0 3.3 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.1 ETN97192.1 - 0.015 15.7 0.0 1 9.9 0.0 3.0 3 0 0 3 3 3 0 HEAT-like repeat Ipi1_N PF12333.3 ETN97192.1 - 0.024 14.6 0.7 0.55 10.2 0.2 2.4 2 1 1 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation BP28CT PF08146.7 ETN97193.1 - 7.4e-07 29.0 0.5 0.18 11.5 0.2 3.3 3 0 0 3 3 3 3 BP28CT (NUC211) domain HEAT_2 PF13646.1 ETN97193.1 - 0.0061 16.8 0.2 0.032 14.5 0.1 2.2 2 0 0 2 2 2 1 HEAT repeats LEDGF PF11467.3 ETN97193.1 - 0.036 13.7 0.3 0.63 9.7 0.0 2.6 2 1 0 3 3 3 0 Lens epithelium-derived growth factor (LEDGF) YbjQ_1 PF01906.12 ETN97193.1 - 0.054 13.9 0.0 0.31 11.4 0.0 2.2 1 1 0 2 2 2 0 Putative heavy-metal-binding Cation_ATPase_C PF00689.16 ETN97194.1 - 2.4e-11 43.5 0.7 3.5e-11 42.9 0.5 1.2 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus DUF3804 PF12707.2 ETN97194.1 - 0.011 15.2 0.2 0.016 14.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3804) Pex14_N PF04695.8 ETN97195.1 - 0.19 11.7 8.6 0.22 11.5 6.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Apc15p PF05841.6 ETN97195.1 - 0.68 10.6 13.8 0.84 10.3 9.6 1.3 1 0 0 1 1 1 0 Apc15p protein Macoilin PF09726.4 ETN97195.1 - 4.7 5.3 6.7 4.8 5.3 4.6 1.0 1 0 0 1 1 1 0 Transmembrane protein Spore_YhcN_YlaJ PF09580.5 ETN97195.1 - 8.3 6.4 16.5 10 6.2 11.4 1.2 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) TMEM219 PF14940.1 ETN97196.1 - 0.056 12.5 0.5 0.14 11.2 0.1 1.8 2 1 0 2 2 2 0 Transmembrane 219 rve PF00665.21 ETN97197.1 - 8.1e-11 42.0 0.0 1.4e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain HYR PF02494.11 ETN97198.1 - 0.073 13.0 0.2 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 HYR domain Dak1_2 PF13684.1 ETN97199.1 - 0.0088 15.0 0.2 0.012 14.5 0.1 1.2 1 0 0 1 1 1 1 Dihydroxyacetone kinase family EnY2 PF10163.4 ETN97199.1 - 0.021 14.7 3.3 0.63 10.0 0.6 2.2 2 0 0 2 2 2 0 Transcription factor e(y)2 PrkA PF06798.7 ETN97199.1 - 0.055 12.7 3.9 0.068 12.4 2.7 1.2 1 0 0 1 1 1 0 PrkA serine protein kinase C-terminal domain RNA_GG_bind PF10258.4 ETN97199.1 - 0.058 13.0 2.7 1.1 8.9 1.9 2.1 1 1 0 1 1 1 0 PHAX RNA-binding domain SPOUT_MTase PF02590.12 ETN97199.1 - 0.12 12.0 3.3 0.061 13.0 1.1 1.4 1 1 1 2 2 2 0 Predicted SPOUT methyltransferase SURF2 PF05477.6 ETN97201.1 - 0.34 10.0 9.9 0.54 9.3 6.9 1.5 1 1 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Cucumo_2B PF03263.8 ETN97202.1 - 0.38 11.0 3.9 0.58 10.4 2.7 1.3 1 0 0 1 1 1 0 Cucumovirus protein 2B DUF4409 PF14365.1 ETN97202.1 - 1.9 8.6 8.4 2.5 8.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4409) Peptidase_S49_N PF08496.5 ETN97202.1 - 2.2 8.0 9.0 4.3 7.1 6.3 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RNB PF00773.14 ETN97203.1 - 0.0039 16.5 6.4 0.0047 16.2 4.5 1.1 1 0 0 1 1 1 1 RNB domain DUF3800 PF12686.2 ETN97203.1 - 0.036 13.6 10.5 0.043 13.4 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3800) tRNA-synt_2e PF02091.10 ETN97204.1 - 0.024 13.7 0.8 0.03 13.4 0.1 1.5 2 0 0 2 2 2 0 Glycyl-tRNA synthetase alpha subunit DUF650 PF04894.7 ETN97204.1 - 0.16 11.4 1.2 1.2 8.5 0.0 2.0 2 0 0 2 2 2 0 Archaeal protein of unknown function (DUF650) CDC50 PF03381.10 ETN97205.1 - 2.3e-24 86.0 2.4 4.3e-24 85.1 1.7 1.5 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family ATP-synt_8 PF00895.15 ETN97208.1 - 0.3 11.3 2.1 0.39 10.9 1.5 1.2 1 0 0 1 1 1 0 ATP synthase protein 8 Serinc PF03348.10 ETN97209.1 - 1.2e-10 40.6 1.9 1.4e-10 40.5 1.3 1.2 1 0 0 1 1 1 1 Serine incorporator (Serinc) UPF0114 PF03350.11 ETN97209.1 - 0.014 15.3 0.3 0.018 14.9 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein family, UPF0114 IBR PF01485.16 ETN97210.1 - 0.18 11.6 3.2 0.43 10.4 2.2 1.8 1 1 0 1 1 1 0 IBR domain DUF2599 PF10783.4 ETN97211.1 - 0.084 13.5 0.5 1.2 9.7 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2599) Peptidase_C14 PF00656.17 ETN97211.1 - 0.09 12.4 0.2 0.23 11.1 0.0 1.6 2 0 0 2 2 2 0 Caspase domain Imm42 PF15601.1 ETN97211.1 - 0.14 11.5 1.1 2.7 7.4 0.0 2.5 1 1 0 2 2 2 0 Immunity protein 42 AAA_assoc_C PF09821.4 ETN97211.1 - 0.6 10.4 2.5 2 8.7 0.3 2.1 2 0 0 2 2 2 0 C-terminal AAA-associated domain WD40 PF00400.27 ETN97212.1 - 6.3e-66 216.0 14.9 2.6e-14 52.4 0.2 6.0 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETN97212.1 - 1.4e-12 47.7 0.2 1.4e-06 28.2 0.0 3.5 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETN97212.1 - 8.9e-08 30.7 2.5 0.045 11.8 0.0 4.5 1 1 4 5 5 5 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETN97212.1 - 1e-06 27.3 0.4 0.0055 15.0 0.0 2.3 1 1 0 2 2 2 2 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 ETN97212.1 - 5.2e-06 25.5 1.4 0.00086 18.2 0.6 2.1 1 1 1 2 2 2 2 Coatomer WD associated region Nucleoporin_N PF08801.6 ETN97212.1 - 1.1e-05 24.3 8.1 0.23 10.1 0.2 4.5 1 1 3 4 4 4 3 Nup133 N terminal like Resistin PF06954.6 ETN97212.1 - 3.7e-05 23.9 0.0 31 4.9 0.0 4.8 2 1 3 5 5 5 0 Resistin DUF4221 PF13970.1 ETN97212.1 - 9.6e-05 21.8 1.0 0.04 13.2 0.0 3.4 1 1 1 3 3 3 1 Domain of unknown function (DUF4221) PQQ_2 PF13360.1 ETN97212.1 - 9.8e-05 21.9 0.1 0.037 13.4 0.0 2.7 2 1 0 2 2 2 1 PQQ-like domain SGL PF08450.7 ETN97212.1 - 0.00019 20.9 0.3 0.0049 16.2 0.0 2.4 1 1 1 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region PD40 PF07676.7 ETN97212.1 - 0.00019 21.0 11.0 1.2 8.8 0.1 5.9 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 ETN97212.1 - 0.00068 18.7 1.0 0.49 9.4 0.0 3.2 2 1 1 3 3 3 1 Protein of unknown function (DUF1258) DUF3892 PF13031.1 ETN97212.1 - 0.0007 19.9 1.6 0.024 15.0 0.2 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF3892) FmdE PF02663.9 ETN97212.1 - 0.0016 18.3 0.9 0.025 14.4 0.2 2.6 1 1 1 2 2 2 1 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Tox-PL PF15644.1 ETN97212.1 - 0.0023 18.6 0.2 8.3 7.1 0.0 3.8 4 1 0 4 4 4 0 Papain fold toxin 1 SusE PF14292.1 ETN97212.1 - 0.0052 16.6 0.0 36 4.2 0.0 4.0 4 0 0 4 4 4 0 SusE outer membrane protein IKI3 PF04762.7 ETN97212.1 - 0.0079 14.0 0.2 0.41 8.3 0.1 2.0 1 1 1 2 2 2 2 IKI3 family B_lectin PF01453.19 ETN97212.1 - 0.0091 15.8 0.4 0.33 10.8 0.0 2.8 1 1 2 3 3 3 1 D-mannose binding lectin DUF1652 PF07865.6 ETN97212.1 - 0.015 14.8 0.4 80 2.9 0.0 4.8 2 2 4 6 6 6 0 Protein of unknown function (DUF1652) Mid2 PF04478.7 ETN97212.1 - 0.097 12.0 3.0 2.8 7.3 0.1 3.2 2 1 1 3 3 3 0 Mid2 like cell wall stress sensor Surfac_D-trimer PF09006.6 ETN97212.1 - 0.17 11.6 0.2 1.8 8.3 0.1 2.8 2 1 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation HEAT_2 PF13646.1 ETN97213.1 - 0.0092 16.2 0.0 0.01 16.1 0.0 1.2 1 0 0 1 1 1 1 HEAT repeats DUF3944 PF13099.1 ETN97213.1 - 0.016 14.6 1.7 0.039 13.4 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3944) U-box PF04564.10 ETN97214.1 - 5.4e-13 48.7 0.1 1.1e-12 47.7 0.1 1.5 1 1 0 1 1 1 1 U-box domain NPR3 PF03666.8 ETN97215.1 - 1.7 7.0 7.6 1.8 6.9 5.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SRI PF08236.6 ETN97216.1 - 0.03 14.2 0.9 0.051 13.5 0.2 1.7 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain Transposase_mut PF00872.13 ETN97217.1 - 0.0055 15.3 0.9 0.0076 14.8 0.6 1.2 1 0 0 1 1 1 1 Transposase, Mutator family Cullin_binding PF03556.10 ETN97217.1 - 0.41 10.7 9.9 0.69 10.0 3.2 2.3 1 1 1 2 2 2 0 Cullin binding Sds3 PF08598.6 ETN97217.1 - 1.4 8.4 6.8 1.7 8.1 4.7 1.3 1 0 0 1 1 1 0 Sds3-like Ada3 PF10198.4 ETN97218.1 - 2.3e-06 27.3 0.1 3.8e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 Secretin_N_2 PF07655.8 ETN97219.1 - 0.92 9.9 6.5 1.6 9.1 4.5 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain TPR_11 PF13414.1 ETN97220.1 - 0.00019 20.9 0.0 0.00044 19.8 0.0 1.6 2 0 0 2 2 2 1 TPR repeat TPR_19 PF14559.1 ETN97220.1 - 0.0027 17.9 0.0 0.0059 16.9 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETN97220.1 - 0.0099 15.7 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETN97220.1 - 0.035 13.9 0.0 0.08 12.8 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETN97220.1 - 0.062 14.0 0.0 0.16 12.7 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETN97220.1 - 0.086 12.4 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 ETN97221.1 - 0.0004 19.9 0.0 0.00093 18.7 0.0 1.6 2 0 0 2 2 2 1 TPR repeat TPR_19 PF14559.1 ETN97221.1 - 0.0027 17.9 0.0 0.0059 16.9 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETN97221.1 - 0.01 15.6 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.1 ETN97221.1 - 0.036 13.9 0.0 0.081 12.7 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETN97221.1 - 0.066 13.9 0.0 0.16 12.7 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETN97221.1 - 0.088 12.4 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat HEAT_2 PF13646.1 ETN97222.1 - 2.8e-09 37.1 0.0 0.039 14.2 0.0 4.0 2 1 2 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 ETN97222.1 - 0.00011 22.5 0.1 3.8 8.1 0.0 4.5 5 1 0 5 5 5 2 HEAT-like repeat HEAT PF02985.17 ETN97222.1 - 0.00044 20.1 1.4 3.8 7.8 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat RF-1 PF00472.15 ETN97222.1 - 0.05 13.3 1.5 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 RF-1 domain Pneumo_matrix PF03393.11 ETN97222.1 - 0.08 11.8 0.9 0.12 11.2 0.6 1.2 1 0 0 1 1 1 0 Pneumovirus matrix protein DUF3944 PF13099.1 ETN97222.1 - 0.19 11.2 5.5 0.64 9.5 0.1 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF3944) INTS5_N PF14837.1 ETN97222.1 - 4.3 6.6 7.8 1 8.6 0.3 2.8 3 1 0 3 3 3 0 Integrator complex subunit 5 N-terminus Cag12 PF13117.1 ETN97223.1 - 0.0095 15.8 2.1 0.04 13.8 1.4 2.0 1 1 1 2 2 2 1 Cag pathogenicity island protein Cag12 NACHT PF05729.7 ETN97225.1 - 1.2e-05 25.0 0.0 2.1e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain DUF3832 PF12909.2 ETN97225.1 - 0.0013 18.7 0.1 0.0062 16.5 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF3832) THDPS_N PF14790.1 ETN97225.1 - 0.087 12.4 1.1 0.47 10.0 0.1 2.2 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal DDHD PF02862.12 ETN97225.1 - 0.15 11.8 4.0 0.21 11.3 2.8 1.2 1 0 0 1 1 1 0 DDHD domain DRY_EERY PF09750.4 ETN97225.1 - 1.7 8.7 9.4 0.82 9.7 4.5 1.8 2 0 0 2 2 2 0 Alternative splicing regulator VWA_2 PF13519.1 ETN97226.1 - 1.9e-07 31.3 0.0 2.7e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain WD40 PF00400.27 ETN97227.1 - 4.9e-32 108.6 14.4 3.7e-12 45.6 0.0 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN97227.1 - 2.5e-08 32.5 3.7 0.0047 15.1 0.2 2.9 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETN97227.1 - 0.0049 15.6 2.7 1.4 7.5 0.6 2.6 1 1 1 2 2 2 2 Nup133 N terminal like DUF3601 PF12208.3 ETN97227.1 - 0.0049 16.7 0.0 0.07 13.0 0.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF3601) DUF4221 PF13970.1 ETN97227.1 - 0.14 11.4 2.7 1.8 7.7 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4221) zf-CCHC_4 PF14392.1 ETN97228.1 - 0.071 12.7 5.2 0.3 10.7 0.5 2.6 1 1 1 2 2 2 0 Zinc knuckle CAP18_C PF12153.3 ETN97228.1 - 0.58 9.8 3.5 1.3 8.6 0.3 2.3 2 0 0 2 2 2 0 LPS binding domain of CAP18 (C terminal) Actin PF00022.14 ETN97229.1 - 4.2e-109 364.5 0.0 3.7e-108 361.4 0.0 1.9 1 1 0 1 1 1 1 Actin zf-TRAF PF02176.13 ETN97231.1 - 2.3e-08 34.3 6.0 2.3e-08 34.3 4.1 1.7 2 0 0 2 2 1 1 TRAF-type zinc finger MalF_P2 PF14785.1 ETN97231.1 - 0.018 14.9 4.5 0.027 14.3 3.1 1.3 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain Sina PF03145.11 ETN97231.1 - 0.13 11.9 5.3 8.8 5.9 1.0 2.7 1 1 0 3 3 3 0 Seven in absentia protein family Kinesin-relat_1 PF12711.2 ETN97231.1 - 0.15 12.5 13.0 0.13 12.6 7.6 2.0 1 1 0 1 1 1 0 Kinesin motor TSC22 PF01166.13 ETN97231.1 - 0.33 10.9 13.3 5.7 6.9 7.8 3.0 2 1 0 2 2 2 0 TSC-22/dip/bun family CCDC155 PF14662.1 ETN97231.1 - 0.34 10.4 15.9 0.21 11.1 10.0 1.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 bZIP_1 PF00170.16 ETN97231.1 - 0.36 10.8 15.4 0.15 12.0 7.2 2.7 2 1 1 3 3 3 0 bZIP transcription factor HALZ PF02183.13 ETN97231.1 - 0.6 9.8 11.9 0.15 11.7 3.6 2.6 1 1 1 2 2 2 0 Homeobox associated leucine zipper DUF904 PF06005.7 ETN97231.1 - 0.96 9.7 21.2 0.42 10.9 12.6 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF904) Shugoshin_N PF07558.6 ETN97231.1 - 1.5 8.5 18.3 0.099 12.3 6.3 2.6 2 1 1 3 3 3 0 Shugoshin N-terminal coiled-coil region Ax_dynein_light PF10211.4 ETN97231.1 - 1.8 8.3 13.3 0.41 10.4 6.4 1.8 2 0 0 2 2 2 0 Axonemal dynein light chain DUF4337 PF14235.1 ETN97231.1 - 2 8.2 5.8 2.6 7.8 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF972 PF06156.8 ETN97231.1 - 4.4 7.7 14.9 4 7.8 8.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF972) GP41 PF00517.12 ETN97231.1 - 6.3 6.2 10.9 9.5 5.7 7.6 1.2 1 0 0 1 1 1 0 Retroviral envelope protein CN_hydrolase PF00795.17 ETN97232.1 - 5.5e-05 22.5 0.1 8.1e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase KfrA_N PF11740.3 ETN97233.1 - 1.4 9.3 5.9 48 4.4 0.2 3.7 3 1 0 3 3 3 0 Plasmid replication region DNA-binding N-term DUF1133 PF06576.6 ETN97234.1 - 0.042 13.0 2.0 0.053 12.7 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1133) EF-hand_4 PF12763.2 ETN97234.1 - 0.052 13.2 1.1 3.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand RSV_NS2 PF03113.9 ETN97234.1 - 0.07 13.0 0.3 0.07 13.0 0.2 1.6 2 0 0 2 2 1 0 Respiratory synctial virus non-structural protein NS2 AAA_11 PF13086.1 ETN97234.1 - 0.11 12.0 6.4 0.13 11.7 4.5 1.2 1 0 0 1 1 1 0 AAA domain DUF413 PF04219.7 ETN97234.1 - 0.14 11.9 0.6 0.27 10.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF TMEM247 PF15444.1 ETN97234.1 - 0.21 11.3 4.2 0.34 10.6 2.9 1.4 1 1 0 1 1 1 0 Transmembrane protein 247 DUF641 PF04859.7 ETN97234.1 - 0.26 11.0 13.4 0.29 10.9 3.1 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Viral_cys_rich PF08008.7 ETN97234.1 - 0.36 10.4 3.5 7.3 6.2 0.1 2.5 2 0 0 2 2 2 0 Viral cysteine rich V-ATPase_G PF03179.10 ETN97234.1 - 0.39 11.0 12.7 0.9 9.8 8.8 1.7 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Tubulin PF00091.20 ETN97234.1 - 0.49 10.1 6.2 0.65 9.7 4.3 1.1 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain NAD_binding_5 PF07994.7 ETN97234.1 - 1.4 8.3 5.0 2 7.8 3.5 1.2 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Laminin_II PF06009.7 ETN97234.1 - 1.4 8.6 11.3 2.9 7.6 7.8 1.5 1 1 1 2 2 2 0 Laminin Domain II PhoU PF01895.14 ETN97234.1 - 1.4 9.3 10.8 0.36 11.2 1.4 2.3 1 1 0 2 2 2 0 PhoU domain Exonuc_VII_L PF02601.10 ETN97234.1 - 1.7 7.7 10.2 2 7.5 7.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATP-synt_F6 PF05511.6 ETN97234.1 - 2.9 7.8 6.5 9.2 6.2 4.1 1.9 1 1 1 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 IncA PF04156.9 ETN97234.1 - 5.5 6.5 14.3 8.2 5.9 9.9 1.3 1 0 0 1 1 1 0 IncA protein hDGE_amylase PF14701.1 ETN97234.1 - 8 5.2 10.6 9.9 4.9 7.4 1.0 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Enkurin PF13864.1 ETN97234.1 - 9.3 6.5 14.1 28 4.9 9.8 1.8 1 1 0 1 1 1 0 Calmodulin-binding zf-RanBP PF00641.13 ETN97235.1 - 0.001 18.1 1.8 0.001 18.1 1.3 1.9 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.10 ETN97235.1 - 0.0022 17.5 0.1 0.0022 17.5 0.1 1.9 2 1 0 2 2 2 1 Sec23/Sec24 zinc finger zf-ribbon_3 PF13248.1 ETN97235.1 - 0.0057 15.8 0.9 0.0057 15.8 0.6 2.4 2 0 0 2 2 2 1 zinc-ribbon domain Ribosomal_L37e PF01907.14 ETN97235.1 - 0.024 14.4 3.5 2.4 8.0 0.2 2.4 2 0 0 2 2 2 0 Ribosomal protein L37e DZR PF12773.2 ETN97235.1 - 0.039 13.7 5.7 0.15 11.9 0.7 2.1 1 1 1 2 2 2 0 Double zinc ribbon UIM PF02809.15 ETN97235.1 - 0.31 10.7 6.7 0.55 9.9 1.3 2.6 2 0 0 2 2 2 0 Ubiquitin interaction motif zinc_ribbon_2 PF13240.1 ETN97235.1 - 2.3 7.8 4.4 0.92 9.0 0.6 2.1 2 0 0 2 2 2 0 zinc-ribbon domain WD40 PF00400.27 ETN97238.1 - 7.6e-05 22.4 0.4 0.00031 20.5 0.2 2.0 2 0 0 2 2 2 1 WD domain, G-beta repeat PT PF04886.7 ETN97240.1 - 0.00089 18.5 70.5 0.0028 16.9 14.6 4.6 1 1 1 2 2 2 1 PT repeat DUF1700 PF08006.6 ETN97241.1 - 0.0017 17.6 0.2 0.0018 17.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1700) HEAT_2 PF13646.1 ETN97242.1 - 6.5e-06 26.3 0.0 0.23 11.7 0.0 3.0 2 1 1 3 3 3 2 HEAT repeats Imm42 PF15601.1 ETN97242.1 - 8.8e-05 21.9 0.4 0.016 14.6 0.2 2.6 2 1 0 2 2 2 2 Immunity protein 42 Syja_N PF02383.13 ETN97242.1 - 0.0071 15.1 4.9 0.014 14.2 0.2 2.2 1 1 0 2 2 2 1 SacI homology domain HEAT PF02985.17 ETN97242.1 - 0.0074 16.2 0.1 46 4.4 0.0 4.6 5 0 0 5 5 5 0 HEAT repeat ENTH PF01417.15 ETN97242.1 - 0.18 11.6 3.3 1.3 8.8 0.5 2.5 2 1 0 2 2 2 0 ENTH domain MMS19_C PF12460.3 ETN97242.1 - 0.67 8.6 4.9 0.7 8.5 0.9 2.0 1 1 0 2 2 2 0 RNAPII transcription regulator C-terminal DUF1043 PF06295.7 ETN97244.1 - 0.22 11.1 6.5 0.2 11.2 3.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) WD40 PF00400.27 ETN97245.1 - 1.3e-19 69.2 3.0 1.1e-09 37.7 0.1 3.2 3 1 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETN97245.1 - 0.002 16.3 0.1 0.36 8.8 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 CTP_transf_2 PF01467.21 ETN97246.1 - 1.6e-05 25.0 0.6 3e-05 24.1 0.1 1.8 2 1 0 2 2 2 1 Cytidylyltransferase DUF4030 PF13222.1 ETN97246.1 - 2.1 8.0 6.0 1.7 8.3 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4030) Profilin PF00235.14 ETN97248.1 - 0.082 13.0 0.3 0.1 12.7 0.2 1.1 1 0 0 1 1 1 0 Profilin AntA PF08346.7 ETN97248.1 - 0.091 12.9 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 AntA/AntB antirepressor Kelch_1 PF01344.20 ETN97249.1 - 1.5e-05 24.4 4.6 0.024 14.1 0.6 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETN97249.1 - 0.00053 20.0 9.4 0.11 12.7 0.6 3.9 4 0 0 4 4 4 2 Kelch motif SelR PF01641.13 ETN97249.1 - 0.0014 18.3 0.2 0.0031 17.1 0.1 1.6 1 0 0 1 1 1 1 SelR domain Kelch_4 PF13418.1 ETN97249.1 - 0.0037 17.0 1.2 0.1 12.3 0.0 3.2 4 1 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETN97249.1 - 0.0073 16.0 1.4 0.43 10.4 0.1 3.2 3 0 0 3 3 3 1 Kelch motif TraD_N PF12615.3 ETN97249.1 - 0.049 13.9 0.6 4 7.8 0.1 2.6 2 0 0 2 2 2 0 F sex factor protein N terminal Kelch_3 PF13415.1 ETN97249.1 - 0.093 12.9 0.5 2.6 8.3 0.0 3.3 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_5 PF13854.1 ETN97249.1 - 0.36 10.8 3.6 0.76 9.7 0.2 2.8 3 0 0 3 3 3 0 Kelch motif Mito_carr PF00153.22 ETN97250.1 - 1.1e-19 69.8 0.6 1.9e-12 46.6 0.0 2.0 1 1 1 2 2 2 2 Mitochondrial carrier protein DUF244 PF03112.9 ETN97251.1 - 0.0027 17.2 4.2 0.0031 17.0 2.9 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (ORF7) DUF HEAT_2 PF13646.1 ETN97253.1 - 0.00078 19.6 0.0 0.084 13.1 0.0 2.2 2 0 0 2 2 2 1 HEAT repeats Cys_rich_FGFR PF00839.12 ETN97253.1 - 0.11 12.4 4.1 1.7 8.6 0.1 3.5 4 0 0 4 4 4 0 Cysteine rich repeat DUF4485 PF14846.1 ETN97253.1 - 1.1 9.0 4.7 22 4.8 0.3 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4485) Kelch_5 PF13854.1 ETN97254.1 - 0.015 15.2 3.6 0.015 15.2 0.5 2.5 3 0 0 3 3 3 0 Kelch motif P2_Phage_GpR PF06891.6 ETN97254.1 - 0.056 13.2 0.0 0.12 12.2 0.0 1.4 2 0 0 2 2 2 0 P2 phage tail completion protein R (GpR) Kelch_2 PF07646.10 ETN97254.1 - 0.097 12.4 0.9 0.78 9.6 0.1 2.8 3 0 0 3 3 3 0 Kelch motif Ras PF00071.17 ETN97255.1 - 4e-06 26.3 0.0 7.4e-06 25.4 0.0 1.4 1 1 0 1 1 1 1 Ras family EGF_MSP1_1 PF12946.2 ETN97255.1 - 0.74 9.6 5.3 1.4 8.7 2.3 2.3 2 0 0 2 2 2 0 MSP1 EGF domain 1 EMP70 PF02990.11 ETN97257.1 - 0.15 10.4 1.3 0.14 10.5 0.9 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 Lipoprotein_10 PF03202.8 ETN97257.1 - 0.62 10.0 6.8 0.74 9.8 4.7 1.1 1 0 0 1 1 1 0 Putative mycoplasma lipoprotein, C-terminal region PBP1_TM PF14812.1 ETN97257.1 - 1.1 9.6 11.4 1.4 9.2 7.9 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ycf1 PF05758.7 ETN97257.1 - 1.3 6.6 11.5 1.4 6.5 8.0 1.0 1 0 0 1 1 1 0 Ycf1 WD40 PF00400.27 ETN97259.1 - 4.5e-21 73.8 13.0 8.5e-11 41.3 1.2 3.2 3 1 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETN97259.1 - 4.3e-06 25.1 0.7 3.4e-05 22.2 0.2 1.9 1 1 0 2 2 2 1 Nucleoporin Nup120/160 SUKH_5 PF14567.1 ETN97259.1 - 0.056 12.9 0.1 0.11 12.0 0.0 1.7 1 1 0 1 1 1 0 SMI1-KNR4 cell-wall DUF3916 PF13079.1 ETN97259.1 - 0.64 9.6 4.6 1.3 8.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3916) CsiD PF08943.5 ETN97260.1 - 0.038 12.8 0.1 0.042 12.7 0.1 1.1 1 0 0 1 1 1 0 CsiD BAAT_C PF08840.6 ETN97260.1 - 0.22 11.2 1.9 0.25 11.0 1.3 1.1 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2344 PF10105.4 ETN97260.1 - 0.33 10.4 2.4 0.4 10.1 1.7 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) DUF406 PF04175.7 ETN97260.1 - 2 8.9 5.4 27 5.3 1.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF406) Prefoldin_2 PF01920.15 ETN97260.1 - 3.6 7.3 10.7 5.9 6.7 4.0 2.1 2 0 0 2 2 2 0 Prefoldin subunit Clat_adaptor_s PF01217.15 ETN97261.1 - 0.008 15.8 0.6 0.012 15.3 0.4 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Herpes_V23 PF01802.12 ETN97261.1 - 0.014 14.4 0.5 0.019 14.0 0.3 1.1 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein Tim44 PF04280.10 ETN97261.1 - 0.022 14.7 0.9 0.029 14.3 0.6 1.3 1 0 0 1 1 1 0 Tim44-like domain DUF2373 PF10180.4 ETN97261.1 - 0.13 11.8 0.9 2.2 7.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2373) Takusan PF04822.8 ETN97261.1 - 0.22 11.2 7.8 0.038 13.7 2.0 2.2 2 1 0 2 2 2 0 Takusan Relaxase PF03432.9 ETN97261.1 - 0.8 9.0 6.7 1 8.7 4.6 1.1 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain DUF2680 PF10925.3 ETN97261.1 - 3.4 7.6 5.4 20 5.1 0.7 3.4 2 2 0 2 2 2 0 Protein of unknown function (DUF2680) Lipoprotein_17 PF04200.7 ETN97263.1 - 0.13 12.4 0.1 0.13 12.4 0.1 2.8 3 1 1 4 4 4 0 Lipoprotein associated domain OmpH PF03938.9 ETN97264.1 - 0.092 12.6 0.1 0.13 12.2 0.1 1.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) AAA_18 PF13238.1 ETN97264.1 - 0.24 11.6 2.3 0.29 11.4 1.6 1.2 1 0 0 1 1 1 0 AAA domain CENP-R PF06729.7 ETN97265.1 - 0.021 14.4 4.6 0.026 14.2 3.2 1.2 1 0 0 1 1 1 0 Kinetochore component, CENP-R Lebercilin PF15619.1 ETN97265.1 - 0.041 13.3 7.4 0.049 13.0 5.1 1.1 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DIX PF00778.12 ETN97265.1 - 0.048 13.3 1.0 0.85 9.3 0.5 2.1 2 0 0 2 2 2 0 DIX domain DUF2443 PF10398.4 ETN97265.1 - 0.081 12.7 5.9 1.4 8.7 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) Syntaxin-6_N PF09177.6 ETN97265.1 - 0.091 13.1 1.4 0.13 12.6 0.9 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DUF4145 PF13643.1 ETN97265.1 - 0.092 12.6 6.1 2.1 8.2 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4145) BLOC1_2 PF10046.4 ETN97265.1 - 0.1 12.7 8.3 0.1 12.7 4.8 1.7 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_Gp111 PF07410.6 ETN97265.1 - 0.13 12.4 1.3 1.9 8.6 0.5 2.3 1 1 1 2 2 2 0 Streptococcus thermophilus bacteriophage Gp111 protein Prominin PF05478.6 ETN97265.1 - 0.16 9.4 2.3 0.18 9.2 1.6 1.1 1 0 0 1 1 1 0 Prominin DUF342 PF03961.8 ETN97265.1 - 0.25 9.6 6.0 0.27 9.6 4.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Mlo PF03094.10 ETN97265.1 - 0.31 9.1 4.3 0.48 8.4 0.0 2.0 1 1 1 2 2 2 0 Mlo family Sec2p PF06428.6 ETN97265.1 - 0.5 10.2 8.0 0.94 9.3 5.6 1.6 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p IR1-M PF12185.3 ETN97265.1 - 0.95 9.2 3.4 0.41 10.3 0.2 2.0 2 1 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain IncA PF04156.9 ETN97265.1 - 1 8.9 8.4 2.1 7.8 5.8 1.6 1 1 0 1 1 1 0 IncA protein Spc24 PF08286.6 ETN97265.1 - 1.3 8.6 6.4 3.5 7.3 4.5 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Prefoldin PF02996.12 ETN97265.1 - 1.5 8.4 9.6 5.2 6.7 0.1 2.5 2 1 1 3 3 3 0 Prefoldin subunit SPAM PF02090.10 ETN97265.1 - 2.7 7.9 8.8 6.4 6.7 0.2 2.3 1 1 1 2 2 2 0 Salmonella surface presentation of antigen gene type M protein Prothymosin PF03247.9 ETN97266.1 - 0.0033 17.5 13.8 0.0041 17.2 9.5 1.2 1 0 0 1 1 1 1 Prothymosin/parathymosin family Myc_N PF01056.13 ETN97266.1 - 0.0044 16.2 10.8 0.0051 16.0 7.5 1.1 1 0 0 1 1 1 1 Myc amino-terminal region Nucleoplasmin PF03066.10 ETN97266.1 - 0.017 14.6 7.9 0.019 14.5 5.5 1.2 1 0 0 1 1 1 0 Nucleoplasmin BSP_II PF05432.6 ETN97266.1 - 0.017 14.4 10.5 0.018 14.3 7.3 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) UPF0564 PF10595.4 ETN97266.1 - 0.033 13.1 9.9 0.037 12.9 6.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 PBP1_TM PF14812.1 ETN97266.1 - 0.086 13.1 5.5 0.11 12.8 3.8 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2890 PF11081.3 ETN97266.1 - 0.1 12.6 9.2 0.12 12.4 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) SPT2 PF08243.6 ETN97266.1 - 0.14 12.4 11.6 0.19 12.0 8.0 1.2 1 0 0 1 1 1 0 SPT2 chromatin protein TFIIF_alpha PF05793.7 ETN97266.1 - 0.14 10.4 15.2 0.17 10.2 10.6 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) VID27 PF08553.5 ETN97266.1 - 0.15 10.2 8.4 0.15 10.2 5.8 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Na_trans_assoc PF06512.8 ETN97266.1 - 0.17 11.8 12.0 0.2 11.6 8.4 1.0 1 0 0 1 1 1 0 Sodium ion transport-associated DUF740 PF05340.7 ETN97266.1 - 0.24 9.7 5.8 0.25 9.6 4.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF740) FAM176 PF14851.1 ETN97266.1 - 0.27 10.9 6.0 0.31 10.7 4.2 1.3 1 0 0 1 1 1 0 FAM176 family Rpp20 PF12328.3 ETN97266.1 - 0.33 10.6 8.0 0.46 10.1 5.6 1.2 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Acyl-thio_N PF12590.3 ETN97266.1 - 0.35 11.3 2.2 0.47 10.9 1.5 1.3 1 0 0 1 1 1 0 Acyl-ATP thioesterase Sporozoite_P67 PF05642.6 ETN97266.1 - 0.47 8.2 7.7 0.5 8.1 5.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Daxx PF03344.10 ETN97266.1 - 0.59 8.5 15.5 0.68 8.3 10.8 1.0 1 0 0 1 1 1 0 Daxx Family Retinal PF15449.1 ETN97266.1 - 0.72 7.4 9.0 0.79 7.2 6.3 1.0 1 0 0 1 1 1 0 Retinal protein DUF3381 PF11861.3 ETN97266.1 - 0.82 9.1 11.8 0.92 9.0 8.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) RNA_pol_3_Rpc31 PF11705.3 ETN97266.1 - 1.1 9.2 10.2 1.2 8.9 7.1 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PPP4R2 PF09184.6 ETN97266.1 - 1.1 8.7 14.0 1.2 8.6 9.7 1.1 1 0 0 1 1 1 0 PPP4R2 Merozoite_SPAM PF07133.6 ETN97266.1 - 1.3 8.9 16.3 1.4 8.7 11.3 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) TRAP_alpha PF03896.11 ETN97266.1 - 1.3 7.9 7.3 1.4 7.8 5.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Paf1 PF03985.8 ETN97266.1 - 1.5 7.5 10.6 1.6 7.4 7.4 1.1 1 0 0 1 1 1 0 Paf1 Prog_receptor PF02161.10 ETN97266.1 - 1.6 7.4 5.4 1.7 7.3 3.7 1.0 1 0 0 1 1 1 0 Progesterone receptor EBV-NA3 PF05009.7 ETN97266.1 - 1.6 7.8 4.9 1.8 7.7 3.4 1.1 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) CDC45 PF02724.9 ETN97266.1 - 1.8 6.5 6.9 1.8 6.5 4.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Spore_coat_CotO PF14153.1 ETN97266.1 - 2.2 7.7 12.8 2.5 7.5 8.8 1.1 1 0 0 1 1 1 0 Spore coat protein CotO RR_TM4-6 PF06459.7 ETN97266.1 - 3.9 7.2 12.1 4.5 7.0 8.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4611 PF15387.1 ETN97266.1 - 4.5 7.5 12.2 5.1 7.3 8.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) Tim54 PF11711.3 ETN97266.1 - 5.8 5.4 8.8 6 5.3 6.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 HSP90 PF00183.13 ETN97266.1 - 6.1 5.1 13.7 6.8 4.9 9.5 1.0 1 0 0 1 1 1 0 Hsp90 protein CENP-B_dimeris PF09026.5 ETN97266.1 - 8.7 6.6 10.6 15 5.8 7.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RelA_SpoT PF04607.12 ETN97268.1 - 0.0015 18.5 1.4 0.0032 17.4 1.0 1.5 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins Pkinase PF00069.20 ETN97270.1 - 2.6e-37 128.4 0.0 6.5e-37 127.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETN97270.1 - 4.4e-21 75.1 0.0 5.8e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETN97270.1 - 2.6e-06 26.6 0.0 5.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family GLYCAM-1 PF05242.6 ETN97271.1 - 0.033 14.1 8.5 0.6 10.0 2.2 2.3 2 0 0 2 2 2 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) Pkinase PF00069.20 ETN97272.1 - 9.1e-17 61.0 0.0 1.3e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain NACHT PF05729.7 ETN97274.1 - 2.8e-06 27.1 0.0 3.2e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETN97274.1 - 0.00033 20.9 0.0 0.00057 20.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETN97274.1 - 0.023 15.5 0.0 0.033 15.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 ETN97274.1 - 0.03 14.4 0.0 0.031 14.4 0.0 1.3 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 ETN97274.1 - 0.066 13.3 0.8 0.78 9.9 0.6 2.1 1 1 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 ETN97274.1 - 0.094 12.4 0.0 1.3 8.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Cytidylate_kin2 PF13189.1 ETN97274.1 - 0.2 11.5 1.0 11 5.9 0.0 2.3 2 1 0 2 2 2 0 Cytidylate kinase-like family DUF1298 PF06974.8 ETN97276.1 - 0.062 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) TPR_MLP1_2 PF07926.7 ETN97277.1 - 0.013 15.2 3.8 0.013 15.2 2.7 3.4 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 ETN97277.1 - 0.078 12.8 43.5 0.15 11.9 18.5 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1411 PF07199.6 ETN97277.1 - 0.25 10.7 8.0 0.53 9.7 5.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1411) Med9 PF07544.8 ETN97277.1 - 0.63 9.8 28.6 0.38 10.5 5.4 3.7 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Spc7 PF08317.6 ETN97277.1 - 1.5 7.4 39.4 1.5 7.3 15.3 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein NPV_P10 PF05531.7 ETN97277.1 - 2.1 8.6 22.1 12 6.2 0.7 4.2 1 1 3 4 4 4 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 ETN97277.1 - 3.1 6.9 16.6 2.7 7.0 8.4 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF2203 PF09969.4 ETN97277.1 - 4.1 7.6 17.8 9.3 6.4 8.3 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) ADIP PF11559.3 ETN97277.1 - 4.8 7.0 35.3 1.8 8.4 15.4 2.7 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding TcdA_TcdB PF12919.2 ETN97277.1 - 8.2 4.7 21.3 3.1 6.1 3.2 2.3 1 1 1 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain DUF3802 PF12290.3 ETN97278.1 - 0.11 12.8 2.5 0.17 12.1 1.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3802) Cnd1_N PF12922.2 ETN97279.1 - 0.00055 19.6 1.0 0.00056 19.5 0.7 1.1 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Baculo_11_kDa PF06143.6 ETN97279.1 - 0.093 12.1 0.4 0.14 11.5 0.3 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family SDH_sah PF01972.11 ETN97279.1 - 0.11 11.3 1.5 0.13 11.0 1.0 1.1 1 0 0 1 1 1 0 Serine dehydrogenase proteinase MFS_2 PF13347.1 ETN97279.1 - 0.16 10.2 0.8 0.17 10.2 0.6 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein RIC3 PF15361.1 ETN97279.1 - 0.59 10.3 6.1 0.86 9.8 4.2 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 MFS_Mycoplasma PF07672.8 ETN97279.1 - 0.64 9.1 4.4 0.71 8.9 3.1 1.1 1 0 0 1 1 1 0 Mycoplasma MFS transporter DUF3685 PF12452.3 ETN97279.1 - 4.7 6.3 6.6 2.2 7.4 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3685) DUF2762 PF10960.3 ETN97279.1 - 5.9 6.6 10.4 5 6.9 5.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2762) WD40 PF00400.27 ETN97280.1 - 1.8e-29 100.4 16.6 8.5e-11 41.3 1.9 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN97280.1 - 1.1e-08 33.6 2.3 0.0023 16.1 0.2 3.0 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETN97280.1 - 0.00013 20.9 4.7 0.094 11.4 0.0 3.0 1 1 0 3 3 3 3 Nup133 N terminal like CRT10 PF08728.5 ETN97280.1 - 0.16 9.9 6.3 0.71 7.7 3.4 1.9 1 1 1 2 2 2 0 CRT10 RNA_pol_Rpb2_7 PF04560.15 ETN97282.1 - 0.17 12.1 0.2 0.53 10.5 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 7 zf-TRAF PF02176.13 ETN97283.1 - 0.0007 19.9 3.7 0.0007 19.9 2.6 1.9 2 0 0 2 2 2 1 TRAF-type zinc finger TPR_MLP1_2 PF07926.7 ETN97283.1 - 0.04 13.6 20.7 4.2 7.1 10.4 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein WEMBL PF05701.6 ETN97283.1 - 0.078 11.4 15.0 0.11 10.9 10.4 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF641 PF04859.7 ETN97283.1 - 0.13 12.0 15.7 0.81 9.4 2.5 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) TBPIP PF07106.8 ETN97283.1 - 0.25 10.8 24.0 0.95 8.9 2.5 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1192 PF06698.6 ETN97283.1 - 0.35 10.7 4.5 8.3 6.3 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) PIG-S PF10510.4 ETN97283.1 - 0.52 8.9 7.8 0.71 8.4 5.4 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein PolyA_pol PF01743.15 ETN97283.1 - 0.53 10.5 3.1 0.96 9.6 2.1 1.4 1 0 0 1 1 1 0 Poly A polymerase head domain Cep57_CLD_2 PF14197.1 ETN97283.1 - 0.64 9.9 11.9 0.93 9.4 4.0 2.7 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Geminin PF07412.7 ETN97283.1 - 1.5 8.5 18.9 0.16 11.6 4.0 2.9 1 1 1 2 2 2 0 Geminin DUF4239 PF14023.1 ETN97283.1 - 1.7 7.9 4.8 1.8 7.9 2.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) DUF4140 PF13600.1 ETN97283.1 - 1.8 9.0 13.6 7 7.1 0.2 3.2 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.10 ETN97283.1 - 2.2 7.8 22.6 1.5 8.3 2.1 3.5 2 1 1 3 3 3 0 Septum formation initiator TSC22 PF01166.13 ETN97283.1 - 3.1 7.8 17.1 1.1 9.2 2.3 3.4 1 1 2 3 3 3 0 TSC-22/dip/bun family DUF972 PF06156.8 ETN97283.1 - 6.4 7.1 17.2 2.6 8.4 4.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TPR_12 PF13424.1 ETN97284.1 - 7.6e-28 96.2 5.4 3.6e-14 52.4 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETN97284.1 - 1.4e-12 47.0 8.5 3.2e-08 33.1 1.2 2.4 1 1 2 3 3 3 2 TPR repeat TPR_1 PF00515.23 ETN97284.1 - 1.5e-11 43.4 6.4 4.3e-06 26.0 0.5 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETN97284.1 - 1.3e-10 40.8 0.0 0.0014 18.5 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETN97284.1 - 9.1e-10 37.6 1.3 0.002 17.7 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETN97284.1 - 1.5e-09 37.0 4.6 0.0019 17.9 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETN97284.1 - 9.3e-09 34.4 9.9 0.0042 16.7 0.2 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETN97284.1 - 0.0003 19.9 0.6 0.87 8.8 0.0 3.4 3 0 0 3 3 3 2 SHNi-TPR TPR_17 PF13431.1 ETN97284.1 - 0.0024 17.9 0.9 25 5.3 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETN97284.1 - 0.0048 17.2 0.5 1.7 9.2 0.0 3.4 3 1 0 3 3 2 1 Tetratricopeptide repeat TPR_3 PF07720.7 ETN97284.1 - 0.024 14.4 4.0 0.072 12.9 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 ETN97284.1 - 0.029 14.2 5.6 0.2 11.5 0.4 2.9 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain RPN7 PF10602.4 ETN97284.1 - 0.036 13.4 1.1 0.11 11.8 0.1 2.2 1 1 1 2 2 2 0 26S proteasome subunit RPN7 TFIIS_M PF07500.9 ETN97284.1 - 0.054 13.5 1.5 0.54 10.3 0.7 2.1 1 1 1 2 2 2 0 Transcription factor S-II (TFIIS), central domain Prefoldin PF02996.12 ETN97284.1 - 0.14 11.8 0.9 7 6.3 0.0 2.2 2 0 0 2 2 2 0 Prefoldin subunit Apc3 PF12895.2 ETN97284.1 - 0.32 11.1 5.4 0.66 10.1 3.1 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 ETN97285.1 - 1.3e-14 53.9 0.1 1.3e-08 34.6 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETN97285.1 - 5e-07 29.4 0.0 0.0012 18.6 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETN97285.1 - 7.6e-07 28.6 0.0 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 TPR repeat TPR_8 PF13181.1 ETN97285.1 - 8.6e-06 25.1 1.5 0.00025 20.6 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETN97285.1 - 1.2e-05 24.8 0.0 0.0021 17.8 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETN97285.1 - 0.00027 20.3 0.3 0.0022 17.5 0.0 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETN97285.1 - 0.004 16.8 0.0 0.018 14.7 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETN97285.1 - 0.048 13.8 1.0 3 8.2 0.1 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat Cobl PF09469.5 ETN97285.1 - 0.075 13.0 1.7 2.1 8.3 0.1 2.4 1 1 2 3 3 3 0 Cordon-bleu ubiquitin-like domain PY_rept_46 PF09689.5 ETN97285.1 - 0.41 11.0 0.2 0.41 11.0 0.1 2.0 2 1 0 2 2 2 0 Plasmodium yoelii repeat (PY_rept_46) Motile_Sperm PF00635.21 ETN97286.1 - 0.2 11.3 4.6 0.36 10.4 3.2 1.5 1 0 0 1 1 1 0 MSP (Major sperm protein) domain Peptidase_S49_N PF08496.5 ETN97286.1 - 9 6.0 7.2 12 5.7 5.0 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DNA_pol3_delta PF06144.8 ETN97288.1 - 0.039 13.4 0.1 0.046 13.2 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Helicase_C_2 PF13307.1 ETN97288.1 - 0.12 12.2 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 Helicase C-terminal domain Nup84_Nup100 PF04121.8 ETN97290.1 - 7.7e-28 96.6 10.7 5e-13 47.6 0.0 3.3 3 0 0 3 3 3 3 Nuclear pore protein 84 / 107 YagB_YeeU_YfjZ PF06154.6 ETN97291.1 - 0.011 15.9 0.1 0.3 11.3 0.0 2.6 1 1 2 3 3 3 0 YagB/YeeU/YfjZ family fn1 PF00039.13 ETN97291.1 - 0.31 10.8 1.1 16 5.3 0.1 2.6 2 1 0 2 2 2 0 Fibronectin type I domain WD40 PF00400.27 ETN97295.1 - 7.2e-29 98.5 18.5 1.3e-10 40.7 0.0 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN97295.1 - 2.4e-07 29.2 0.6 0.037 12.1 0.0 3.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETN97295.1 - 0.1 11.9 2.8 0.46 9.7 1.4 2.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4221) CAP_GLY PF01302.20 ETN97296.1 - 0.058 13.0 0.1 8.1 6.2 0.0 2.4 2 0 0 2 2 2 0 CAP-Gly domain CENP-B_dimeris PF09026.5 ETN97296.1 - 0.62 10.3 5.0 2.6 8.3 1.2 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 ETN97296.1 - 1.2 8.6 6.3 1.4 8.4 1.5 2.3 2 0 0 2 2 2 0 Nucleoplasmin FG-GAP PF01839.18 ETN97298.1 - 4e-13 48.6 2.4 2.4e-06 27.0 0.4 2.4 2 0 0 2 2 2 2 FG-GAP repeat VCBS PF13517.1 ETN97298.1 - 1.2e-07 31.9 8.6 2.3e-06 27.8 2.6 2.0 1 1 1 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.3 ETN97298.1 - 0.00044 19.7 0.1 0.062 12.7 0.0 2.1 1 1 1 2 2 2 2 Insecticide toxin TcdB middle/N-terminal region RGS PF00615.14 ETN97299.1 - 3.7e-07 30.2 2.4 5.2e-07 29.7 1.6 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain SPA PF08616.5 ETN97299.1 - 0.067 12.9 0.2 0.14 11.8 0.1 1.7 1 1 0 1 1 1 0 Stabilization of polarity axis HEAT_2 PF13646.1 ETN97302.1 - 1.5e-17 63.5 0.1 9e-07 29.0 0.0 2.7 1 1 2 3 3 3 3 HEAT repeats HEAT PF02985.17 ETN97302.1 - 4.4e-15 54.3 0.0 0.0002 21.1 0.0 4.6 4 1 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.1 ETN97302.1 - 5.9e-11 42.5 0.0 0.0022 18.4 0.0 4.2 2 1 2 4 4 4 2 HEAT-like repeat UME PF08064.8 ETN97302.1 - 1.4e-05 24.9 0.2 0.25 11.3 0.0 3.6 1 1 0 2 2 2 1 UME (NUC010) domain DUF3554 PF12074.3 ETN97302.1 - 3.9e-05 23.2 4.2 0.2 11.0 0.0 3.0 1 1 2 3 3 3 2 Domain of unknown function (DUF3554) DUF2608 PF11019.3 ETN97302.1 - 8.2e-05 21.7 4.4 0.096 11.6 0.1 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF2608) Cnd1 PF12717.2 ETN97302.1 - 0.00019 21.3 2.9 0.0035 17.2 2.0 2.7 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.5 ETN97302.1 - 0.00027 20.5 1.1 0.13 11.8 0.1 2.7 1 1 1 2 2 2 2 TATA-binding protein interacting (TIP20) Adaptin_N PF01602.15 ETN97302.1 - 0.00043 18.7 1.2 0.0008 17.8 0.3 1.4 1 1 0 1 1 1 1 Adaptin N terminal region DUF2435 PF10363.4 ETN97302.1 - 0.0015 18.4 0.5 0.096 12.5 0.1 2.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2435) IFRD PF05004.8 ETN97302.1 - 0.0016 17.6 1.2 0.091 11.8 0.0 2.8 1 1 2 3 3 3 1 Interferon-related developmental regulator (IFRD) XkdW PF09636.5 ETN97302.1 - 0.0023 17.8 2.8 0.29 11.0 0.0 3.1 2 1 1 3 3 3 1 XkdW protein Vac14_Fab1_bd PF12755.2 ETN97302.1 - 0.0049 17.2 0.2 0.95 9.8 0.0 2.7 1 1 1 2 2 2 1 Vacuolar 14 Fab1-binding region MOR2-PAG1_C PF14225.1 ETN97302.1 - 0.0064 16.2 2.2 2.9 7.5 0.1 3.0 1 1 2 3 3 3 1 Cell morphogenesis C-terminal DUF3385 PF11865.3 ETN97302.1 - 0.0066 16.3 0.2 32 4.4 0.0 4.0 3 2 1 4 4 4 0 Domain of unknown function (DUF3385) CRM1_C PF08767.6 ETN97302.1 - 0.0082 15.1 0.6 0.77 8.6 0.0 2.7 1 1 1 2 2 2 1 CRM1 C terminal Glycos_trans_3N PF02885.12 ETN97302.1 - 0.011 15.3 0.9 51 3.5 0.0 4.0 3 1 1 4 4 4 0 Glycosyl transferase family, helical bundle domain MMS19_N PF14500.1 ETN97302.1 - 0.012 14.9 0.6 0.21 10.8 0.1 2.2 1 1 2 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_PBS PF03130.11 ETN97302.1 - 0.013 15.8 0.0 97 3.8 0.0 4.5 4 1 0 4 4 4 0 PBS lyase HEAT-like repeat MMS19_C PF12460.3 ETN97302.1 - 0.015 14.0 4.1 0.09 11.4 2.8 2.8 1 1 0 1 1 1 0 RNAPII transcription regulator C-terminal ArgJ PF01960.13 ETN97302.1 - 0.017 13.5 0.1 1.5 7.1 0.0 2.3 1 1 1 2 2 2 0 ArgJ family ThylakoidFormat PF11264.3 ETN97302.1 - 0.017 14.7 2.2 0.2 11.2 0.1 2.7 1 1 2 3 3 3 0 Thylakoid formation protein DrsE PF02635.10 ETN97302.1 - 0.022 14.7 1.8 0.1 12.6 0.2 2.3 1 1 2 3 3 3 0 DsrE/DsrF-like family Evr1_Alr PF04777.8 ETN97302.1 - 0.027 14.3 0.1 0.11 12.4 0.0 2.0 1 1 1 2 2 2 0 Erv1 / Alr family Activator-TraM PF11657.3 ETN97302.1 - 0.038 13.4 2.7 0.2 11.1 0.0 2.6 1 1 1 3 3 3 0 Transcriptional activator TraM Symplekin_C PF12295.3 ETN97302.1 - 0.038 13.8 1.7 1.9 8.3 0.1 2.6 1 1 0 2 2 2 0 Symplekin tight junction protein C terminal CART PF06373.6 ETN97302.1 - 0.041 13.8 1.0 6.1 6.8 0.1 3.1 3 0 0 3 3 3 0 Cocaine and amphetamine regulated transcript protein (CART) DUF4428 PF14471.1 ETN97302.1 - 0.048 13.4 3.8 1.2 8.8 0.3 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4428) TGT PF01702.13 ETN97302.1 - 0.056 12.7 0.1 0.2 10.8 0.0 1.9 1 1 1 2 2 2 0 Queuine tRNA-ribosyltransferase K-box PF01486.12 ETN97302.1 - 0.06 13.1 2.8 0.098 12.4 0.2 2.2 2 0 0 2 2 2 0 K-box region DUF445 PF04286.7 ETN97302.1 - 0.062 12.8 3.2 0.17 11.4 2.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF445) zf-C4_ClpX PF06689.8 ETN97302.1 - 0.072 12.6 0.2 0.18 11.3 0.1 1.6 1 0 0 1 1 1 0 ClpX C4-type zinc finger DUF2758 PF10957.3 ETN97302.1 - 0.078 12.8 4.9 0.98 9.2 0.1 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF2758) Prp18 PF02840.10 ETN97302.1 - 0.1 12.4 3.1 3.6 7.3 0.1 3.0 1 1 2 3 3 3 0 Prp18 domain RNA_binding PF01877.12 ETN97302.1 - 0.18 11.7 2.0 5.5 7.0 0.1 3.1 1 1 1 3 3 3 0 RNA binding DUF2922 PF11148.3 ETN97302.1 - 0.21 11.2 1.3 0.97 9.1 0.1 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF2922) PMC2NT PF08066.7 ETN97304.1 - 0.017 15.3 1.5 0.017 15.3 1.0 2.6 2 1 1 3 3 3 0 PMC2NT (NUC016) domain V_ATPase_I PF01496.14 ETN97304.1 - 0.11 10.3 14.3 0.15 9.9 9.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MCPsignal PF00015.16 ETN97304.1 - 0.25 10.8 10.0 0.45 10.0 2.6 2.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Laminin_II PF06009.7 ETN97304.1 - 0.36 10.5 15.5 20 4.9 10.7 2.3 1 1 0 1 1 1 0 Laminin Domain II Nup54 PF13874.1 ETN97304.1 - 0.51 10.0 14.9 0.15 11.7 2.7 2.3 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 AAA_13 PF13166.1 ETN97304.1 - 0.57 8.5 22.3 0.8 8.0 15.4 1.2 1 0 0 1 1 1 0 AAA domain Prominin PF05478.6 ETN97304.1 - 0.97 6.8 10.2 1.4 6.3 7.1 1.3 1 0 0 1 1 1 0 Prominin Seryl_tRNA_N PF02403.17 ETN97304.1 - 1 9.4 27.9 2.7 8.0 11.3 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain COG2 PF06148.6 ETN97304.1 - 1.6 8.5 12.7 3.9 7.3 1.3 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Tho2 PF11262.3 ETN97304.1 - 5.2 6.0 17.2 9.2 5.2 7.8 2.2 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 ATP-synt_B PF00430.13 ETN97304.1 - 5.6 6.7 23.2 4 7.2 5.4 2.5 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DUF4446 PF14584.1 ETN97304.1 - 7.5 6.3 15.5 2.7 7.8 1.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) GvpG PF05120.7 ETN97304.1 - 8 6.3 12.4 8.3 6.3 4.9 2.6 2 1 0 2 2 2 0 Gas vesicle protein G TPR_12 PF13424.1 ETN97305.1 - 4e-14 52.3 0.0 5.5e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETN97305.1 - 2.9e-11 42.3 10.0 1.6e-09 36.8 0.8 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETN97305.1 - 3e-11 42.3 2.0 1.2e-07 31.0 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETN97305.1 - 5.1e-09 35.3 4.5 8.3e-07 28.3 0.7 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETN97305.1 - 8e-08 31.8 0.7 1.6e-07 30.8 0.5 1.5 1 0 0 1 1 1 1 TPR repeat TPR_7 PF13176.1 ETN97305.1 - 1.1e-06 28.0 0.1 0.00063 19.3 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETN97305.1 - 2.9e-05 23.8 0.0 0.0084 16.0 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETN97305.1 - 0.00026 21.2 0.1 0.00095 19.4 0.1 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETN97305.1 - 0.00072 19.5 8.6 0.038 14.1 0.0 4.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETN97305.1 - 0.0015 18.9 0.0 0.13 12.9 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_21 PF09976.4 ETN97305.1 - 0.0019 18.1 0.1 0.004 17.0 0.0 1.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETN97305.1 - 0.0031 17.7 0.0 0.0093 16.2 0.0 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat MIT PF04212.13 ETN97305.1 - 0.0032 17.3 1.6 0.0032 17.3 1.1 1.6 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain Mob_Pre PF01076.14 ETN97305.1 - 0.019 14.5 1.0 0.019 14.5 0.7 2.1 1 1 1 2 2 2 0 Plasmid recombination enzyme TPR_16 PF13432.1 ETN97305.1 - 0.034 14.8 0.0 0.065 13.9 0.0 1.5 1 1 0 1 1 1 0 Tetratricopeptide repeat Sel1 PF08238.7 ETN97305.1 - 0.11 13.2 0.1 0.24 12.0 0.1 1.6 1 0 0 1 1 1 0 Sel1 repeat Apc3 PF12895.2 ETN97305.1 - 0.14 12.2 3.4 0.17 12.0 0.6 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Endotoxin_N PF03945.9 ETN97305.1 - 2.4 7.4 6.8 3.5 6.9 4.7 1.4 1 1 0 1 1 1 0 delta endotoxin, N-terminal domain Nitroreductase PF00881.19 ETN97307.1 - 0.1 12.4 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 Nitroreductase family Rdx PF10262.4 ETN97307.1 - 0.1 12.6 0.0 0.13 12.3 0.0 1.3 1 1 0 1 1 1 0 Rdx family CAP_N PF01213.14 ETN97309.1 - 3.4e-05 23.2 2.6 3.4e-05 23.2 1.8 1.8 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) N terminal 4HBT_3 PF13622.1 ETN97309.1 - 0.00045 20.0 0.3 0.00052 19.8 0.2 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Mito_fiss_reg PF05308.6 ETN97309.1 - 0.00058 19.3 8.1 0.00058 19.3 5.6 1.6 2 0 0 2 2 2 1 Mitochondrial fission regulator LPP20 PF02169.11 ETN97309.1 - 0.0016 18.4 0.0 0.7 10.0 0.0 3.3 1 1 2 4 4 4 1 LPP20 lipoprotein Kinetocho_Slk19 PF12709.2 ETN97309.1 - 0.54 10.3 9.5 0.046 13.8 2.3 2.5 2 2 1 3 3 3 0 Central kinetochore-associated SlyX PF04102.7 ETN97309.1 - 2.2 8.7 9.2 24 5.3 6.4 2.7 1 1 0 1 1 1 0 SlyX Cys_rich_VLP PF14194.1 ETN97311.1 - 0.051 13.3 0.3 0.086 12.5 0.2 1.3 1 0 0 1 1 1 0 Cysteine-rich VLP Pkinase PF00069.20 ETN97313.1 - 1.1e-06 27.9 0.0 1.3e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain DUF2772 PF10970.3 ETN97314.1 - 0.064 13.3 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2772) UPF0564 PF10595.4 ETN97315.1 - 0.038 12.9 8.0 0.049 12.5 5.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 AAA_21 PF13304.1 ETN97315.1 - 0.43 10.4 8.9 0.53 10.2 6.2 1.0 1 0 0 1 1 1 0 AAA domain Kelch_6 PF13964.1 ETN97316.1 - 1.5e-07 31.2 1.5 2.4e-05 24.3 0.3 2.4 1 1 1 2 2 2 2 Kelch motif Kelch_1 PF01344.20 ETN97316.1 - 1.3e-05 24.5 2.4 5.5e-05 22.6 0.4 2.2 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.1 ETN97316.1 - 3.5e-05 23.4 0.5 0.011 15.4 0.1 2.3 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETN97316.1 - 4.2e-05 23.1 0.3 0.0016 18.1 0.3 2.2 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETN97316.1 - 0.015 15.4 0.1 0.057 13.5 0.0 2.0 2 0 0 2 2 2 0 Galactose oxidase, central domain WD40 PF00400.27 ETN97317.1 - 7.5e-11 41.4 0.3 1.4e-10 40.6 0.2 1.5 1 0 0 1 1 1 1 WD domain, G-beta repeat Nup160 PF11715.3 ETN97317.1 - 0.00045 18.4 0.1 0.00056 18.1 0.1 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 FANCL_C PF11793.3 ETN97318.1 - 0.0024 17.8 2.1 0.0031 17.4 0.0 2.3 3 0 0 3 3 3 1 FANCL C-terminal domain DUF2500 PF10694.4 ETN97319.1 - 0.00071 19.5 0.8 0.0029 17.5 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2500) TAF1D PF15333.1 ETN97319.1 - 0.0093 15.7 5.1 0.0093 15.7 3.5 1.9 2 0 0 2 2 2 1 TATA box-binding protein-associated factor 1D Oxidored_q3 PF00499.15 ETN97319.1 - 0.031 14.0 0.1 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Asp23 PF03780.8 ETN97319.1 - 0.044 14.0 0.1 0.063 13.5 0.0 1.1 1 0 0 1 1 1 0 Asp23 family RIC3 PF15361.1 ETN97319.1 - 0.23 11.6 10.8 0.058 13.6 1.3 2.1 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 O-antigen_lig PF13425.1 ETN97319.1 - 0.28 11.1 1.8 6.5 6.7 0.1 2.1 2 0 0 2 2 2 0 O-antigen ligase like membrane protein P12 PF12669.2 ETN97319.1 - 0.31 11.2 3.5 1.4 9.1 0.2 2.3 2 0 0 2 2 2 0 Virus attachment protein p12 family ELO PF01151.13 ETN97319.1 - 0.41 9.9 5.3 1 8.6 0.1 2.1 2 0 0 2 2 2 0 GNS1/SUR4 family EphA2_TM PF14575.1 ETN97319.1 - 0.65 10.4 2.1 0.9 9.9 0.2 2.0 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF2011 PF09428.5 ETN97319.1 - 0.74 9.7 11.3 0.39 10.6 5.3 2.0 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF2011) DUF2762 PF10960.3 ETN97319.1 - 2.5 7.8 7.3 4.5 7.0 2.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2762) DUF1754 PF08555.5 ETN97319.1 - 3.1 8.4 16.9 0.27 11.8 3.7 2.1 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) APG6 PF04111.7 ETN97320.1 - 1.6 7.6 24.3 0.2 10.6 6.1 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 bZIP_2 PF07716.10 ETN97320.1 - 2.7 7.8 16.1 4.1 7.2 1.7 3.3 2 1 1 3 3 3 0 Basic region leucine zipper IncA PF04156.9 ETN97320.1 - 7.2 6.1 20.9 32 4.0 13.0 2.4 1 1 1 2 2 2 0 IncA protein WD40 PF00400.27 ETN97321.1 - 1.8e-49 163.9 20.3 2.3e-11 43.1 0.3 5.7 5 1 1 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETN97321.1 - 4.2e-07 28.4 1.0 0.037 12.1 0.0 3.3 2 1 1 4 4 4 3 Nucleoporin Nup120/160 Hira PF07569.6 ETN97321.1 - 0.00019 20.7 1.1 0.47 9.6 0.0 2.9 2 1 0 2 2 2 2 TUP1-like enhancer of split PD40 PF07676.7 ETN97321.1 - 0.00062 19.3 0.4 2 8.1 0.0 3.6 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 ETN97321.1 - 0.016 14.2 1.0 0.42 9.6 0.1 2.4 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 ETN97321.1 - 0.029 13.1 2.3 0.57 8.8 0.6 2.7 1 1 1 2 2 2 0 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETN97321.1 - 0.046 12.0 0.1 0.1 10.8 0.1 1.5 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF1191 PF06697.7 ETN97321.1 - 0.16 10.7 0.2 0.25 10.1 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) SF-assemblin PF06705.6 ETN97323.1 - 0.0026 16.9 3.7 0.0027 16.8 2.6 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin HSBP1 PF06825.7 ETN97323.1 - 0.0052 16.3 1.9 0.0052 16.3 1.3 1.5 2 0 0 2 2 2 1 Heat shock factor binding protein 1 NPV_P10 PF05531.7 ETN97323.1 - 0.007 16.5 4.0 0.0079 16.4 2.3 1.3 1 1 0 1 1 1 1 Nucleopolyhedrovirus P10 protein SNARE PF05739.14 ETN97323.1 - 0.0089 15.6 1.7 0.017 14.8 1.2 1.5 1 0 0 1 1 1 1 SNARE domain IncA PF04156.9 ETN97323.1 - 0.019 14.5 3.2 0.018 14.6 2.2 1.1 1 0 0 1 1 1 0 IncA protein DNA_repr_REX1B PF14966.1 ETN97323.1 - 0.026 14.8 0.2 0.026 14.8 0.1 1.2 1 0 0 1 1 1 0 DNA repair REX1-B Cauli_AT PF03233.8 ETN97323.1 - 0.026 14.2 2.1 0.027 14.1 1.5 1.2 1 0 0 1 1 1 0 Aphid transmission protein COG2 PF06148.6 ETN97323.1 - 0.033 14.0 0.7 0.038 13.8 0.5 1.0 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 FliD_C PF07195.7 ETN97323.1 - 0.034 13.4 2.8 0.035 13.3 1.9 1.0 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Vps51 PF08700.6 ETN97323.1 - 0.038 13.8 1.2 0.059 13.2 0.9 1.3 1 0 0 1 1 1 0 Vps51/Vps67 Prefoldin PF02996.12 ETN97323.1 - 0.039 13.6 3.4 0.044 13.4 2.2 1.3 1 1 0 1 1 1 0 Prefoldin subunit AATF-Che1 PF13339.1 ETN97323.1 - 0.039 14.1 0.7 0.039 14.1 0.5 1.1 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor DASH_Dad3 PF08656.5 ETN97323.1 - 0.047 13.3 2.2 0.056 13.1 1.5 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad3 SapB_1 PF05184.10 ETN97323.1 - 0.051 13.4 4.9 1.1 9.1 0.1 2.7 2 1 1 3 3 3 0 Saposin-like type B, region 1 Prominin PF05478.6 ETN97323.1 - 0.054 11.0 1.2 0.049 11.1 0.8 1.0 1 0 0 1 1 1 0 Prominin YlbD_coat PF14071.1 ETN97323.1 - 0.06 13.4 2.4 0.06 13.4 1.7 1.2 1 0 0 1 1 1 0 Putative coat protein DivIC PF04977.10 ETN97323.1 - 0.073 12.5 1.8 0.094 12.2 1.2 1.2 1 0 0 1 1 1 0 Septum formation initiator GLE1 PF07817.8 ETN97323.1 - 0.11 11.4 3.8 0.11 11.4 2.6 1.0 1 0 0 1 1 1 0 GLE1-like protein IDO PF01231.13 ETN97323.1 - 0.11 10.8 0.5 0.11 10.8 0.4 1.0 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase MerR-DNA-bind PF09278.6 ETN97323.1 - 0.12 12.8 0.6 0.15 12.4 0.4 1.4 1 1 0 1 1 1 0 MerR, DNA binding DUF1664 PF07889.7 ETN97323.1 - 0.12 12.1 3.6 0.12 12.1 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Pox_A_type_inc PF04508.7 ETN97323.1 - 0.12 12.2 0.4 0.12 12.2 0.3 2.0 2 1 0 2 2 1 0 Viral A-type inclusion protein repeat Plant_NMP1 PF06694.6 ETN97323.1 - 0.13 11.1 0.7 0.14 11.0 0.5 1.1 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) Ded_cyto PF06920.8 ETN97323.1 - 0.16 11.2 2.0 0.18 11.0 1.4 1.0 1 0 0 1 1 1 0 Dedicator of cytokinesis Fib_alpha PF08702.5 ETN97323.1 - 0.18 11.9 4.2 0.18 11.9 2.9 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.14 ETN97323.1 - 0.18 9.6 1.3 0.17 9.6 0.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 ETN97323.1 - 0.19 12.0 2.1 0.28 11.5 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Hemagglutinin PF00509.13 ETN97323.1 - 0.21 9.6 1.7 0.21 9.6 1.1 1.0 1 0 0 1 1 1 0 Haemagglutinin Lzipper-MIP1 PF14389.1 ETN97323.1 - 0.51 10.4 5.0 0.54 10.3 2.5 1.7 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DASH_Hsk3 PF08227.6 ETN97323.1 - 1.7 8.8 4.1 8.4 6.6 1.6 2.4 2 1 0 2 2 2 0 DASH complex subunit Hsk3 like EpsG PF14897.1 ETN97325.1 - 0.031 13.1 0.1 0.042 12.7 0.1 1.1 1 0 0 1 1 1 0 EpsG family DUF1510 PF07423.6 ETN97325.1 - 0.079 12.3 24.8 0.1 11.9 17.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Neur_chan_memb PF02932.11 ETN97325.1 - 0.084 12.7 5.3 0.11 12.3 3.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2486 PF10667.4 ETN97325.1 - 0.087 13.3 7.7 0.11 13.0 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) CDC45 PF02724.9 ETN97325.1 - 5.2 4.9 11.9 5.9 4.7 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 ETN97326.1 - 1.1e-06 26.7 15.4 1.3e-06 26.5 10.7 1.1 1 0 0 1 1 1 1 Ycf1 MIP-T3 PF10243.4 ETN97326.1 - 2.1e-06 26.5 30.4 2.5e-06 26.2 21.0 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Spore_coat_CotO PF14153.1 ETN97326.1 - 2.8e-06 26.9 21.2 4e-06 26.3 14.7 1.3 1 0 0 1 1 1 1 Spore coat protein CotO Nop14 PF04147.7 ETN97326.1 - 4.2e-05 21.7 25.8 4.2e-05 21.7 17.9 1.6 2 0 0 2 2 2 1 Nop14-like family SAPS PF04499.10 ETN97326.1 - 0.00021 20.0 9.5 0.00028 19.6 6.6 1.3 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein PLRV_ORF5 PF01690.12 ETN97326.1 - 0.0038 16.4 11.6 0.0041 16.3 8.1 1.1 1 0 0 1 1 1 1 Potato leaf roll virus readthrough protein Tim54 PF11711.3 ETN97326.1 - 0.0048 15.5 13.1 0.0082 14.7 9.1 1.4 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 CAF-1_p150 PF11600.3 ETN97326.1 - 0.0058 16.0 50.9 0.0088 15.4 35.3 1.3 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal NPR3 PF03666.8 ETN97326.1 - 0.011 14.3 17.8 0.017 13.6 12.3 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SDA1 PF05285.7 ETN97326.1 - 0.017 14.4 29.6 0.024 13.9 20.5 1.2 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 ETN97326.1 - 0.05 12.0 33.2 0.073 11.5 23.0 1.2 1 0 0 1 1 1 0 Daxx Family DHHW PF14286.1 ETN97326.1 - 0.053 12.8 10.2 0.072 12.3 7.1 1.3 1 0 0 1 1 1 0 DHHW protein Raftlin PF15250.1 ETN97326.1 - 0.086 11.3 14.2 0.13 10.7 9.8 1.2 1 0 0 1 1 1 0 Raftlin DDRGK PF09756.4 ETN97326.1 - 0.092 12.1 40.9 0.17 11.2 28.3 1.4 1 0 0 1 1 1 0 DDRGK domain Caldesmon PF02029.10 ETN97326.1 - 0.11 10.8 37.2 0.14 10.5 25.8 1.1 1 0 0 1 1 1 0 Caldesmon Parvo_coat PF00740.13 ETN97326.1 - 0.34 9.8 10.3 0.45 9.4 7.1 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DUF4045 PF13254.1 ETN97326.1 - 0.35 10.1 20.2 0.49 9.6 14.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Neur_chan_memb PF02932.11 ETN97326.1 - 0.36 10.6 11.9 0.61 9.9 8.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Vfa1 PF08432.5 ETN97326.1 - 0.5 10.3 32.6 0.86 9.5 22.6 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SprA-related PF12118.3 ETN97326.1 - 0.58 9.4 30.0 0.81 8.9 20.8 1.2 1 0 0 1 1 1 0 SprA-related family DUF3807 PF12720.2 ETN97326.1 - 0.89 9.6 28.3 1.4 9.0 19.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) CobT PF06213.7 ETN97326.1 - 1.2 8.1 33.7 1.8 7.6 23.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Presenilin PF01080.12 ETN97326.1 - 1.3 7.7 11.4 1.9 7.2 7.9 1.3 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.7 ETN97326.1 - 1.4 8.7 31.7 2.3 8.0 22.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pilt PF15453.1 ETN97326.1 - 2.1 7.9 20.6 2.9 7.4 14.3 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions UPF0560 PF10577.4 ETN97326.1 - 2.1 6.5 11.4 2.7 6.1 7.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 GAGA_bind PF06217.7 ETN97326.1 - 2.7 7.9 18.0 3.9 7.3 12.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2413 PF10310.4 ETN97326.1 - 2.7 6.6 29.1 3.9 6.1 20.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF2201_N PF13203.1 ETN97326.1 - 2.8 7.0 17.7 3.9 6.5 12.3 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF262 PF03235.9 ETN97326.1 - 2.9 7.8 17.3 0.73 9.7 9.6 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF262 AvrE PF11725.3 ETN97326.1 - 3 4.7 14.4 3.6 4.4 10.0 1.0 1 0 0 1 1 1 0 Pathogenicity factor POP1 PF06978.6 ETN97326.1 - 3 7.4 16.8 31 4.1 0.0 2.4 2 0 0 2 2 2 0 Ribonucleases P/MRP protein subunit POP1 HSP70 PF00012.15 ETN97326.1 - 3 5.6 21.1 3.8 5.3 14.6 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF940 PF06082.6 ETN97326.1 - 5 5.5 6.8 5.8 5.3 4.7 1.1 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) Zip PF02535.17 ETN97326.1 - 5.5 5.8 15.1 11 4.8 10.5 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter BTV_NS2 PF04514.7 ETN97326.1 - 5.6 5.7 26.9 9 5.0 18.6 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CDC27 PF09507.5 ETN97326.1 - 6.3 5.9 41.0 9.9 5.2 28.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 FLO_LFY PF01698.11 ETN97326.1 - 6.5 5.4 21.1 9.7 4.9 14.6 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Paramyxo_ncap PF00973.14 ETN97326.1 - 7.6 5.1 15.3 10 4.6 10.6 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Astro_capsid PF03115.9 ETN97326.1 - 7.8 4.6 12.0 10 4.2 8.3 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Rtf2 PF04641.7 ETN97326.1 - 8.7 5.4 26.4 13 4.8 18.3 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger FAM60A PF15396.1 ETN97326.1 - 9.9 5.8 15.9 17 5.0 11.0 1.4 1 0 0 1 1 1 0 Protein Family FAM60A AIG1 PF04548.11 ETN97328.1 - 7.7e-22 77.4 0.0 1.5e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 ETN97328.1 - 8.6e-10 38.5 0.0 2.3e-09 37.2 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 ETN97328.1 - 3.1e-06 27.1 1.6 0.007 16.2 0.0 3.2 3 0 0 3 3 3 2 Dynamin family DUF258 PF03193.11 ETN97328.1 - 5.7e-05 22.3 0.0 0.00013 21.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 ETN97328.1 - 9.4e-05 22.8 0.0 0.00027 21.4 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein MIB_HERC2 PF06701.8 ETN97328.1 - 0.00013 21.8 1.7 0.00028 20.8 1.2 1.6 1 0 0 1 1 1 1 Mib_herc2 GTP_EFTU PF00009.22 ETN97328.1 - 0.0024 17.3 0.7 1.2 8.5 0.0 3.0 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 ETN97328.1 - 0.023 14.8 0.0 0.07 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 ETN97328.1 - 0.027 14.0 0.1 1.7 8.1 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein DUF975 PF06161.6 ETN97328.1 - 0.036 13.8 1.0 1.8 8.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF975) FtsK_SpoIIIE PF01580.13 ETN97328.1 - 0.049 13.1 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 ETN97328.1 - 0.077 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 ETN97328.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain FeoB_N PF02421.13 ETN97328.1 - 0.1 11.8 0.0 0.5 9.6 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.4 ETN97328.1 - 0.17 11.3 0.4 6.9 6.1 0.1 3.1 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 ETN97328.1 - 0.28 11.4 0.1 0.28 11.4 0.0 3.0 3 2 0 3 3 3 0 AAA domain TrbL PF04610.9 ETN97330.1 - 4.8e-07 29.6 3.4 6.6e-07 29.2 2.4 1.2 1 0 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein NMT PF01233.14 ETN97330.1 - 0.049 13.2 0.1 0.11 12.0 0.0 1.6 1 1 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain WEMBL PF05701.6 ETN97331.1 - 1.7e-05 23.5 13.9 2e-05 23.2 9.6 1.0 1 0 0 1 1 1 1 Weak chloroplast movement under blue light DUF904 PF06005.7 ETN97331.1 - 8e-05 22.8 28.1 0.0024 18.1 3.3 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF904) Phage_GP20 PF06810.6 ETN97331.1 - 0.0034 16.8 4.4 0.0034 16.8 3.1 2.9 1 1 2 3 3 3 1 Phage minor structural protein GP20 Ead_Ea22 PF13935.1 ETN97331.1 - 0.0044 17.3 7.7 0.025 14.9 3.4 2.5 1 1 1 2 2 2 1 Ead/Ea22-like protein Vps51 PF08700.6 ETN97331.1 - 0.011 15.5 7.9 1.8 8.4 0.0 3.5 2 2 1 3 3 3 0 Vps51/Vps67 DUF3450 PF11932.3 ETN97331.1 - 0.013 14.7 2.3 0.013 14.7 1.6 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) bZIP_1 PF00170.16 ETN97331.1 - 0.027 14.4 22.4 0.096 12.6 2.1 3.5 3 1 0 3 3 3 0 bZIP transcription factor DUF4618 PF15397.1 ETN97331.1 - 0.038 13.3 17.8 0.26 10.5 1.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) Phage_B PF02304.10 ETN97331.1 - 0.043 14.1 1.6 0.057 13.7 0.5 1.7 1 1 0 1 1 1 0 Scaffold protein B ADIP PF11559.3 ETN97331.1 - 0.044 13.6 22.9 0.26 11.1 2.3 3.1 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding L31 PF09784.4 ETN97331.1 - 0.057 13.4 0.2 0.057 13.4 0.1 2.4 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L31 DUF972 PF06156.8 ETN97331.1 - 0.093 13.0 21.1 0.7 10.2 2.4 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF972) Cortex-I_coil PF09304.5 ETN97331.1 - 0.11 12.5 17.2 1.9 8.5 7.4 2.3 2 0 0 2 2 2 0 Cortexillin I, coiled coil Seryl_tRNA_N PF02403.17 ETN97331.1 - 0.12 12.4 20.8 0.35 10.8 4.2 2.9 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Tropomyosin_1 PF12718.2 ETN97331.1 - 0.15 11.8 19.2 0.05 13.4 8.0 2.1 2 0 0 2 2 2 0 Tropomyosin like TBPIP PF07106.8 ETN97331.1 - 0.19 11.2 21.8 0.57 9.7 9.0 2.8 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1192 PF06698.6 ETN97331.1 - 0.22 11.3 7.6 1.8 8.4 0.6 3.4 3 1 1 4 4 3 0 Protein of unknown function (DUF1192) BLOC1_2 PF10046.4 ETN97331.1 - 0.24 11.5 13.5 1.3 9.2 1.3 3.2 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CCDC155 PF14662.1 ETN97331.1 - 0.26 10.8 23.8 10 5.6 16.5 2.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 LLC1 PF14945.1 ETN97331.1 - 0.27 11.5 4.8 0.46 10.8 0.1 2.5 2 1 1 3 3 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Reo_sigmaC PF04582.7 ETN97331.1 - 0.3 10.2 5.2 0.38 9.8 1.1 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein GAS PF13851.1 ETN97331.1 - 0.3 10.2 23.6 0.39 9.8 12.6 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.15 ETN97331.1 - 0.3 10.8 23.0 2 8.2 2.6 3.3 2 1 1 3 3 3 0 Prefoldin subunit Prefoldin PF02996.12 ETN97331.1 - 0.31 10.7 16.1 1.9 8.1 1.6 3.3 3 0 0 3 3 3 0 Prefoldin subunit THOC7 PF05615.8 ETN97331.1 - 0.36 11.0 17.8 6 7.1 0.2 2.6 2 1 0 2 2 2 0 Tho complex subunit 7 Striatin PF08232.7 ETN97331.1 - 0.39 11.0 19.5 0.079 13.2 6.2 2.2 1 1 1 2 2 2 0 Striatin family DUF848 PF05852.6 ETN97331.1 - 0.6 9.9 14.3 0.65 9.8 4.7 2.7 2 1 1 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) RPN7 PF10602.4 ETN97331.1 - 0.78 9.1 5.9 5.4 6.3 0.0 2.7 2 1 1 3 3 3 0 26S proteasome subunit RPN7 HAUS-augmin3 PF14932.1 ETN97331.1 - 0.83 8.7 22.8 1.6 7.8 9.4 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Nup54 PF13874.1 ETN97331.1 - 0.86 9.2 15.9 0.1 12.2 2.1 3.0 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 DivIVA PF05103.8 ETN97331.1 - 0.87 9.6 19.3 0.51 10.3 2.5 3.0 1 1 1 2 2 2 0 DivIVA protein CENP-F_leu_zip PF10473.4 ETN97331.1 - 0.97 9.2 22.4 5.5 6.8 11.1 2.8 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PIN_4 PF13638.1 ETN97331.1 - 1 9.4 11.9 4.4 7.4 0.6 2.1 2 0 0 2 2 2 0 PIN domain DUF465 PF04325.8 ETN97331.1 - 1.1 9.0 6.2 10 5.9 0.1 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF465) Orthopox_A5L PF06193.6 ETN97331.1 - 1.2 9.0 13.6 3 7.7 0.7 2.2 1 1 1 2 2 2 0 Orthopoxvirus A5L protein-like ERM PF00769.14 ETN97331.1 - 1.3 8.5 18.5 0.35 10.3 8.4 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family ABC_tran_2 PF12848.2 ETN97331.1 - 1.5 8.7 11.6 0.17 11.7 0.9 2.5 2 1 1 3 3 3 0 ABC transporter TMF_DNA_bd PF12329.3 ETN97331.1 - 2 8.2 24.1 1.2 9.0 4.2 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Mnd1 PF03962.10 ETN97331.1 - 2 8.0 20.3 1.7e+02 1.7 14.0 2.3 1 1 0 1 1 1 0 Mnd1 family KLRAQ PF10205.4 ETN97331.1 - 2.1 8.4 19.5 0.041 13.9 3.6 3.0 1 1 1 3 3 3 0 Predicted coiled-coil domain-containing protein Kinetocho_Slk19 PF12709.2 ETN97331.1 - 2.2 8.4 16.0 2.4 8.2 0.1 3.7 2 1 1 3 3 3 0 Central kinetochore-associated Nnf1 PF03980.9 ETN97331.1 - 2.2 8.2 15.8 9.6 6.2 6.3 3.3 1 1 1 2 2 2 0 Nnf1 TPR_MLP1_2 PF07926.7 ETN97331.1 - 2.3 7.9 23.1 2.3 7.9 5.0 2.9 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DivIC PF04977.10 ETN97331.1 - 2.4 7.6 20.3 5.8 6.4 5.3 3.8 2 1 1 3 3 3 0 Septum formation initiator DUF342 PF03961.8 ETN97331.1 - 2.5 6.4 16.5 1.9 6.7 7.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF4200 PF13863.1 ETN97331.1 - 2.5 8.0 19.7 0.37 10.7 1.1 3.3 2 1 0 3 3 3 0 Domain of unknown function (DUF4200) Phage_lysis PF03245.8 ETN97331.1 - 2.5 8.0 14.1 1.6 8.7 5.0 2.6 3 0 0 3 3 2 0 Bacteriophage Rz lysis protein GrpE PF01025.14 ETN97331.1 - 2.8 7.4 16.0 1.8 8.0 3.4 2.9 2 1 1 3 3 3 0 GrpE DUF1664 PF07889.7 ETN97331.1 - 3 7.6 13.5 1.2 8.9 2.9 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Cep57_MT_bd PF06657.8 ETN97331.1 - 3 7.8 13.6 0.76 9.7 0.3 3.4 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF883 PF05957.8 ETN97331.1 - 3.3 8.1 8.8 7.8 6.9 0.2 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Prp19 PF08606.6 ETN97331.1 - 3.6 7.3 8.4 3 7.6 0.2 3.2 3 0 0 3 3 3 0 Prp19/Pso4-like GvpK PF05121.7 ETN97331.1 - 4.1 7.2 11.4 1.8 8.4 0.1 3.3 2 1 0 3 3 3 0 Gas vesicle protein K Spc24 PF08286.6 ETN97331.1 - 4.2 7.0 24.8 0.78 9.4 5.4 3.1 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 Cep57_CLD_2 PF14197.1 ETN97331.1 - 4.3 7.3 19.9 14 5.6 0.2 3.5 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Ax_dynein_light PF10211.4 ETN97331.1 - 4.5 7.0 20.7 9 6.0 8.0 2.9 2 1 0 2 2 2 0 Axonemal dynein light chain COG2 PF06148.6 ETN97331.1 - 4.9 7.0 11.5 16 5.3 0.1 2.8 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 NPV_P10 PF05531.7 ETN97331.1 - 6.6 7.0 10.5 2.3e+02 2.1 0.0 3.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein YlqD PF11068.3 ETN97331.1 - 6.8 6.7 22.0 2.5 8.1 10.3 2.4 1 1 1 2 2 2 0 YlqD protein Exonuc_VII_L PF02601.10 ETN97331.1 - 7 5.7 13.6 8.5 5.4 9.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit IFT20 PF14931.1 ETN97331.1 - 7.1 6.5 14.2 1.5 8.7 0.3 2.9 1 1 2 3 3 3 0 Intraflagellar transport complex B, subunit 20 APG6 PF04111.7 ETN97331.1 - 8.4 5.3 22.1 79 2.1 15.3 1.9 1 1 0 1 1 1 0 Autophagy protein Apg6 Vfa1 PF08432.5 ETN97331.1 - 9.1 6.2 14.3 15 5.5 4.3 2.0 1 1 1 2 2 2 0 AAA-ATPase Vps4-associated protein 1 KMP11 PF03037.11 ETN97332.1 - 0.0082 16.7 0.1 0.011 16.3 0.0 1.2 1 0 0 1 1 1 1 Kinetoplastid membrane protein 11 HEAT PF02985.17 ETN97334.1 - 0.00024 20.9 0.0 0.0057 16.6 0.0 2.8 3 0 0 3 3 3 1 HEAT repeat PhoU_div PF01865.11 ETN97334.1 - 0.098 11.8 0.0 0.21 10.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF47 DUF972 PF06156.8 ETN97335.1 - 0.00041 20.6 3.0 0.00051 20.3 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF972) MAGSP PF03082.9 ETN97335.1 - 0.0014 18.0 3.8 0.0017 17.7 2.6 1.2 1 0 0 1 1 1 1 Male accessory gland secretory protein bZIP_1 PF00170.16 ETN97335.1 - 0.0015 18.4 1.5 0.0015 18.4 1.0 2.1 3 0 0 3 3 3 1 bZIP transcription factor DivIC PF04977.10 ETN97335.1 - 0.0063 15.9 1.2 0.0063 15.9 0.9 1.6 2 0 0 2 2 2 1 Septum formation initiator TSC22 PF01166.13 ETN97335.1 - 0.009 15.9 1.4 2.6 8.0 0.2 2.5 1 1 1 2 2 2 2 TSC-22/dip/bun family DUF465 PF04325.8 ETN97335.1 - 0.041 13.6 0.5 0.041 13.6 0.4 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF465) DUF2968 PF11180.3 ETN97335.1 - 0.063 12.6 0.3 0.077 12.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Ax_dynein_light PF10211.4 ETN97335.1 - 0.12 12.1 3.3 0.15 11.8 2.3 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain AATF-Che1 PF13339.1 ETN97335.1 - 0.12 12.4 3.4 0.16 12.1 2.4 1.3 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Kinesin-relat_1 PF12711.2 ETN97335.1 - 0.17 12.2 2.0 0.27 11.6 0.6 1.8 1 1 1 2 2 2 0 Kinesin motor CCDC155 PF14662.1 ETN97335.1 - 0.18 11.4 4.4 0.2 11.2 3.0 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 Myosin_tail_1 PF01576.14 ETN97335.1 - 0.48 8.0 6.4 0.5 8.0 4.5 1.0 1 0 0 1 1 1 0 Myosin tail FlxA PF14282.1 ETN97335.1 - 0.71 9.8 9.2 8 6.4 0.7 2.0 1 1 0 1 1 1 0 FlxA-like protein FlaC_arch PF05377.6 ETN97335.1 - 0.77 9.7 4.9 0.74 9.7 2.4 1.8 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF904 PF06005.7 ETN97335.1 - 0.91 9.8 5.1 1.9 8.8 3.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF2205 PF10224.4 ETN97335.1 - 1.5 8.4 6.8 0.074 12.6 0.9 1.7 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) CMS1 PF14617.1 ETN97337.1 - 0.02 13.9 8.6 0.021 13.8 6.0 1.0 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF2661 PF10860.3 ETN97337.1 - 0.038 14.1 4.0 0.053 13.7 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2661) DUF1168 PF06658.7 ETN97337.1 - 0.042 13.3 13.9 0.043 13.3 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) SR-25 PF10500.4 ETN97337.1 - 1.5 8.2 15.6 1.5 8.2 10.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Rib_recp_KP_reg PF05104.7 ETN97337.1 - 1.6 9.2 15.8 1.8 9.0 10.9 1.2 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Carboxyl_trans PF01039.17 ETN97337.1 - 1.7 6.9 3.9 1.8 6.7 2.7 1.0 1 0 0 1 1 1 0 Carboxyl transferase domain G-alpha PF00503.15 ETN97338.1 - 4.1e-45 154.1 5.3 4.9e-45 153.8 3.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETN97338.1 - 3.1e-10 39.5 0.3 6.1e-10 38.6 0.2 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETN97338.1 - 0.00096 18.3 0.3 0.0011 18.1 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 ETN97338.1 - 0.002 17.3 0.1 0.0033 16.6 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 ETN97338.1 - 0.069 13.6 0.1 0.29 11.6 0.0 2.0 1 1 1 2 2 2 0 Miro-like protein Pox_polyA_pol_N PF12630.2 ETN97338.1 - 0.81 9.8 3.8 1.4 9.0 2.6 1.5 1 1 0 1 1 1 0 Poxvirus poly(A) polymerase N-terminal domain WWE PF02825.15 ETN97339.1 - 0.24 10.8 2.2 2 7.9 1.5 2.2 1 1 0 1 1 1 0 WWE domain Sec62 PF03839.11 ETN97339.1 - 0.3 10.4 5.1 0.45 9.8 3.5 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Scm3 PF10384.4 ETN97341.1 - 0.39 10.2 13.2 0.78 9.2 0.1 4.8 5 0 0 5 5 5 0 Centromere protein Scm3 WD40 PF00400.27 ETN97342.1 - 8.2e-27 92.0 4.8 8.6e-11 41.2 0.0 4.4 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN97342.1 - 5.6e-05 21.4 0.1 0.043 11.9 0.0 2.6 1 1 1 2 2 2 2 Nucleoporin Nup120/160 KduI PF04962.7 ETN97342.1 - 0.0069 15.4 0.0 0.009 15.1 0.0 1.2 1 0 0 1 1 1 1 KduI/IolB family NKWYS PF10364.4 ETN97342.1 - 0.039 13.7 0.2 0.064 12.9 0.1 1.3 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein DUF1541 PF07563.6 ETN97342.1 - 0.057 13.0 0.0 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1541) Ribosomal_L21e PF01157.13 ETN97342.1 - 0.13 12.1 1.5 3.9 7.3 0.1 2.4 1 1 1 2 2 2 0 Ribosomal protein L21e PT PF04886.7 ETN97344.1 - 2.7e-26 90.5 133.2 3.4e-07 29.4 9.9 7.9 3 2 4 7 7 7 5 PT repeat RAP PF08373.5 ETN97345.1 - 0.036 13.8 0.4 0.036 13.8 0.3 1.7 2 0 0 2 2 2 0 RAP domain FAST_1 PF06743.10 ETN97346.1 - 0.045 13.4 0.1 0.75 9.5 0.0 2.7 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 DUF342 PF03961.8 ETN97346.1 - 0.7 8.2 7.6 0.99 7.7 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Zip PF02535.17 ETN97347.1 - 0.31 9.9 1.8 0.51 9.2 1.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CIAPIN1 PF05093.8 ETN97348.1 - 0.0072 16.3 3.4 0.014 15.5 2.4 1.4 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF3819 PF12842.2 ETN97350.1 - 0.015 14.9 0.4 0.017 14.8 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) TPR_12 PF13424.1 ETN97353.1 - 6.8e-50 166.9 8.6 3.3e-20 71.7 0.3 3.8 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETN97353.1 - 1.5e-24 85.0 0.0 2.8e-08 33.4 0.0 4.2 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETN97353.1 - 3.4e-22 76.4 4.6 3.5e-08 32.6 0.1 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETN97353.1 - 1e-21 76.3 8.8 1.5e-12 46.9 0.1 4.0 3 1 1 4 4 4 2 TPR repeat TPR_1 PF00515.23 ETN97353.1 - 1e-18 66.0 14.7 9e-07 28.2 0.2 4.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETN97353.1 - 8.8e-17 59.6 7.2 5e-05 22.9 0.1 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETN97353.1 - 1.1e-16 59.2 17.1 2.1e-07 30.2 0.6 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETN97353.1 - 1.5e-07 31.8 0.0 0.037 14.7 0.0 3.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETN97353.1 - 1.1e-06 28.6 4.3 0.079 13.4 0.1 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETN97353.1 - 3.4e-06 26.7 4.4 0.4 11.0 0.4 4.8 4 2 0 4 4 4 2 Tetratricopeptide repeat PPR PF01535.15 ETN97353.1 - 8.4e-06 25.4 0.8 0.95 9.5 0.0 4.1 4 0 0 4 4 4 2 PPR repeat TPR_14 PF13428.1 ETN97353.1 - 1.7e-05 25.0 0.0 3.8 8.4 0.0 4.4 4 1 1 5 5 4 1 Tetratricopeptide repeat DUF2225 PF09986.4 ETN97353.1 - 0.0002 20.8 3.8 0.013 15.0 2.6 2.1 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) Sel1 PF08238.7 ETN97353.1 - 0.0058 17.2 5.9 0.53 11.0 0.2 3.5 3 0 0 3 3 3 1 Sel1 repeat MIT PF04212.13 ETN97353.1 - 0.0096 15.7 12.3 0.12 12.3 0.8 4.2 4 1 1 5 5 5 1 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 ETN97353.1 - 0.012 15.6 8.6 0.21 11.7 2.3 2.7 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.4 ETN97353.1 - 0.032 13.6 4.0 2 7.7 0.1 2.8 3 1 0 3 3 3 0 26S proteasome subunit RPN7 DUF627 PF04781.7 ETN97353.1 - 0.048 13.2 1.9 0.15 11.6 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF627) NSF PF02071.15 ETN97353.1 - 0.67 10.7 13.2 4.2 8.3 0.1 4.4 4 0 0 4 4 3 0 Aromatic-di-Alanine (AdAR) repeat MTHFR PF02219.12 ETN97354.1 - 0.0031 16.6 0.6 0.0057 15.7 0.2 1.6 1 1 0 1 1 1 1 Methylenetetrahydrofolate reductase Peptidase_S39 PF02122.10 ETN97354.1 - 0.072 12.3 1.0 0.14 11.5 0.7 1.6 1 0 0 1 1 1 0 Peptidase S39 Ribosomal_L22 PF00237.14 ETN97354.1 - 0.095 12.6 9.3 2.7 7.9 0.8 3.8 2 1 1 3 3 3 0 Ribosomal protein L22p/L17e AAA_13 PF13166.1 ETN97354.1 - 0.11 10.9 34.0 0.15 10.5 23.6 1.3 1 0 0 1 1 1 0 AAA domain DUF1192 PF06698.6 ETN97354.1 - 0.3 10.9 4.4 0.83 9.5 0.2 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) V_ATPase_I PF01496.14 ETN97354.1 - 1.2 6.9 31.9 0.08 10.7 10.5 2.3 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Fzo_mitofusin PF04799.8 ETN97354.1 - 1.6 8.0 28.0 14 5.0 8.3 3.4 1 1 1 2 2 2 0 fzo-like conserved region TPR_MLP1_2 PF07926.7 ETN97354.1 - 1.7 8.4 41.2 1.2 8.8 12.9 3.3 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DASH_Dam1 PF08653.5 ETN97354.1 - 2.1 8.1 6.4 1.8 8.3 0.2 3.4 3 1 0 3 3 3 0 DASH complex subunit Dam1 Prefoldin_3 PF13758.1 ETN97354.1 - 4.4 7.1 22.9 0.87 9.3 1.0 3.6 2 1 1 3 3 3 0 Prefoldin subunit Spectrin PF00435.16 ETN97354.1 - 4.4 7.6 32.1 3.1 8.1 9.1 3.7 2 2 2 4 4 4 0 Spectrin repeat Antibiotic_NAT PF02522.9 ETN97354.1 - 6.6 5.9 8.0 0.65 9.1 0.9 2.3 2 2 0 2 2 2 0 Aminoglycoside 3-N-acetyltransferase DUF3246 PF11596.3 ETN97356.1 - 0.094 11.9 9.2 0.12 11.6 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Daxx PF03344.10 ETN97356.1 - 0.19 10.1 13.0 0.2 10.1 9.0 1.0 1 0 0 1 1 1 0 Daxx Family NAM-associated PF14303.1 ETN97356.1 - 0.24 11.6 11.8 0.31 11.3 8.2 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF2201_N PF13203.1 ETN97356.1 - 0.32 10.1 6.9 0.36 9.9 4.8 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Sporozoite_P67 PF05642.6 ETN97356.1 - 0.42 8.4 11.1 0.48 8.2 7.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Spt5_N PF11942.3 ETN97356.1 - 0.62 10.7 13.9 0.9 10.2 9.6 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal CDC45 PF02724.9 ETN97356.1 - 2.4 6.1 14.1 2.6 5.9 9.8 1.1 1 0 0 1 1 1 0 CDC45-like protein eIF-3c_N PF05470.7 ETN97356.1 - 2.8 5.9 14.1 3.5 5.6 9.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus YqfQ PF14181.1 ETN97356.1 - 5.7 6.9 7.6 8.3 6.4 5.3 1.3 1 0 0 1 1 1 0 YqfQ-like protein Sec62 PF03839.11 ETN97356.1 - 7.5 5.8 11.1 9.2 5.5 7.7 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF2722 PF10846.3 ETN97356.1 - 8.5 5.2 15.5 11 4.9 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DnaB_2 PF07261.6 ETN97357.1 - 0.05 13.2 0.4 0.05 13.2 0.3 2.2 2 1 1 3 3 3 0 Replication initiation and membrane attachment Peptidase_C65 PF10275.4 ETN97358.1 - 0.04 13.2 0.8 0.15 11.4 0.6 1.7 1 1 0 1 1 1 0 Peptidase C65 Otubain AAA PF00004.24 ETN97359.1 - 0.0001 22.5 0.0 0.00042 20.5 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETN97359.1 - 0.00032 20.4 0.0 0.00087 19.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 ETN97359.1 - 0.0013 19.0 1.1 0.0088 16.3 0.0 2.7 2 1 0 2 2 2 1 ABC transporter AAA_22 PF13401.1 ETN97359.1 - 0.0015 18.6 0.2 0.026 14.6 0.0 3.1 2 1 2 4 4 4 1 AAA domain AAA_16 PF13191.1 ETN97359.1 - 0.0018 18.3 0.0 0.24 11.3 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 ETN97359.1 - 0.0024 17.7 1.2 0.014 15.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain Tenui_N PF05733.6 ETN97359.1 - 0.0039 16.5 0.0 0.008 15.5 0.0 1.5 1 0 0 1 1 1 1 Tenuivirus/Phlebovirus nucleocapsid protein DUF815 PF05673.8 ETN97359.1 - 0.0047 15.8 0.0 0.012 14.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DUF258 PF03193.11 ETN97359.1 - 0.0053 15.9 0.0 0.014 14.5 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 NACHT PF05729.7 ETN97359.1 - 0.01 15.5 3.2 1.6 8.4 0.1 3.5 3 1 0 3 3 3 1 NACHT domain Arch_ATPase PF01637.13 ETN97359.1 - 0.013 15.2 5.7 0.2 11.3 0.0 4.0 4 1 0 4 4 4 0 Archaeal ATPase PduV-EutP PF10662.4 ETN97359.1 - 0.041 13.3 0.1 0.096 12.1 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activ_2 PF14532.1 ETN97359.1 - 0.075 13.0 0.0 0.47 10.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_23 PF13476.1 ETN97359.1 - 0.24 11.6 0.0 0.24 11.6 0.0 3.6 2 1 0 2 2 1 0 AAA domain DUF2222 PF09984.4 ETN97360.1 - 0.015 14.7 1.0 0.088 12.2 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized signal transduction histidine kinase domain (DUF2222) Urm1 PF09138.6 ETN97360.1 - 0.25 11.4 2.5 0.41 10.8 1.7 1.6 1 1 0 1 1 1 0 Urm1 (Ubiquitin related modifier) Syd PF07348.7 ETN97361.1 - 0.015 14.6 1.4 0.016 14.5 0.9 1.0 1 0 0 1 1 1 0 Syd protein (SUKH-2) DUF128 PF01995.11 ETN97361.1 - 0.061 12.2 1.2 0.064 12.1 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF128 Microtub_bind PF13931.1 ETN97361.1 - 0.12 12.4 0.7 0.14 12.2 0.5 1.0 1 0 0 1 1 1 0 Kinesin-associated microtubule-binding Archease PF01951.11 ETN97361.1 - 0.18 11.7 1.3 0.18 11.7 0.9 1.0 1 0 0 1 1 1 0 Archease protein family (MTH1598/TM1083) KBP_C PF12309.3 ETN97362.1 - 0.0013 17.7 0.4 0.0015 17.5 0.3 1.1 1 0 0 1 1 1 1 KIF-1 binding protein C terminal CUE PF02845.11 ETN97362.1 - 0.0019 17.6 0.2 0.0052 16.2 0.1 1.7 1 0 0 1 1 1 1 CUE domain Sipho_Gp157 PF05565.6 ETN97362.1 - 0.026 14.0 7.7 0.059 12.9 5.3 1.5 1 0 0 1 1 1 0 Siphovirus Gp157 Syntaxin_2 PF14523.1 ETN97362.1 - 1.4 8.9 7.5 0.6 10.1 2.7 2.1 2 0 0 2 2 2 0 Syntaxin-like protein IncA PF04156.9 ETN97362.1 - 7.7 6.0 7.3 5.5 6.5 3.3 1.8 2 0 0 2 2 2 0 IncA protein HC2 PF07382.6 ETN97363.1 - 0.0074 16.1 13.7 0.0081 16.0 9.5 1.1 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Arrestin_C PF02752.17 ETN97363.1 - 0.43 10.6 9.0 11 6.0 6.3 2.0 1 1 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain DUF4551 PF15087.1 ETN97363.1 - 0.78 8.0 12.1 0.86 7.8 8.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF4554 PF15091.1 ETN97363.1 - 5.2 5.6 7.9 5.6 5.5 5.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Pex24p PF06398.6 ETN97365.1 - 0.0093 14.7 0.5 0.011 14.4 0.3 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin NARP1 PF12569.3 ETN97365.1 - 2.5 6.7 13.8 3 6.4 9.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3987 PF13148.1 ETN97365.1 - 3.8 5.9 7.3 4.9 5.6 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Peptidase_C14 PF00656.17 ETN97366.1 - 1.2e-06 28.3 4.8 3.8e-06 26.7 0.9 2.6 2 1 0 2 2 2 1 Caspase domain DUF3584 PF12128.3 ETN97370.1 - 0.052 10.8 32.0 0.074 10.3 22.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF972 PF06156.8 ETN97370.1 - 1.9 8.8 0.0 1.9 8.8 0.0 4.0 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Reo_sigmaC PF04582.7 ETN97370.1 - 2.6 7.1 7.9 4.7 6.2 1.3 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein JmjN PF02375.12 ETN97372.1 - 0.13 11.7 0.3 0.45 10.0 0.1 2.0 2 0 0 2 2 2 0 jmjN domain TPR_12 PF13424.1 ETN97373.1 - 5.4e-37 125.5 8.7 2e-22 78.9 0.5 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETN97373.1 - 1.3e-24 85.3 0.1 2.2e-07 30.5 0.0 3.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETN97373.1 - 2.2e-21 74.5 12.3 9.4e-10 37.6 1.1 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETN97373.1 - 9.1e-21 72.0 6.9 2.6e-08 33.1 0.3 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETN97373.1 - 4.9e-20 70.9 8.7 3.5e-14 52.1 2.0 2.3 1 1 0 2 2 2 2 TPR repeat TPR_8 PF13181.1 ETN97373.1 - 8.7e-18 62.7 15.0 1.7e-07 30.4 1.1 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETN97373.1 - 2.9e-16 57.9 0.5 1.8e-05 24.1 0.0 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETN97373.1 - 4.3e-10 39.2 0.0 0.012 16.1 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETN97373.1 - 2.8e-09 37.3 0.1 0.00023 21.7 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETN97373.1 - 5.5e-09 35.8 0.4 0.0086 16.4 0.0 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETN97373.1 - 4e-08 32.3 0.0 0.015 14.5 0.0 3.2 3 0 0 3 3 3 2 SHNi-TPR TPR_17 PF13431.1 ETN97373.1 - 1.9e-06 27.5 13.1 0.0028 17.7 1.2 4.0 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETN97373.1 - 1.2e-05 25.5 0.1 0.001 19.3 0.1 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat DUF627 PF04781.7 ETN97373.1 - 4e-05 23.1 1.2 0.17 11.4 0.2 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF627) MIT PF04212.13 ETN97373.1 - 4.1e-05 23.3 5.0 0.0037 17.1 0.2 3.0 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain SNAP PF14938.1 ETN97373.1 - 7.1e-05 22.0 1.8 0.00018 20.7 1.3 1.8 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP Apc3 PF12895.2 ETN97373.1 - 0.0002 21.4 7.1 0.011 15.7 2.0 2.6 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Sel1 PF08238.7 ETN97373.1 - 0.0041 17.7 0.9 3.5 8.3 0.0 3.1 3 0 0 3 3 3 1 Sel1 repeat DUF2225 PF09986.4 ETN97373.1 - 0.0096 15.3 2.2 0.051 13.0 0.2 1.9 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) CBM_21 PF03370.8 ETN97373.1 - 0.062 13.2 3.0 0.24 11.4 2.1 1.8 1 1 0 1 1 1 0 Putative phosphatase regulatory subunit GBP_C PF02841.9 ETN97373.1 - 0.11 11.7 0.3 1.7 7.7 0.0 2.2 2 1 1 3 3 3 0 Guanylate-binding protein, C-terminal domain DUF3856 PF12968.2 ETN97373.1 - 0.13 12.0 0.3 0.76 9.5 0.1 2.1 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) Rab5-bind PF09311.6 ETN97373.1 - 0.14 12.0 0.0 0.37 10.6 0.0 1.6 2 0 0 2 2 2 0 Rabaptin-like protein Serpin PF00079.15 ETN97373.1 - 0.15 11.1 0.3 0.18 10.9 0.2 1.1 1 0 0 1 1 1 0 Serpin (serine protease inhibitor) NYD-SP28_assoc PF14775.1 ETN97373.1 - 0.3 10.8 1.7 22 4.8 0.0 2.9 3 0 0 3 3 3 0 Sperm tail C-terminal domain NSF PF02071.15 ETN97373.1 - 0.59 10.9 3.1 30 5.8 0.1 3.3 3 0 0 3 3 2 0 Aromatic-di-Alanine (AdAR) repeat Sec5 PF15469.1 ETN97373.1 - 5.2 6.7 9.1 36 4.0 3.4 2.9 2 1 0 2 2 2 0 Exocyst complex component Sec5 Ubiq-assoc PF09145.5 ETN97373.1 - 5.6 6.9 7.2 5.3 6.9 0.1 3.3 3 2 0 3 3 3 0 Ubiquitin-associated UVR PF02151.14 ETN97373.1 - 9.8 5.8 8.4 5.3 6.7 0.1 3.7 4 1 0 4 4 4 0 UvrB/uvrC motif NEMO PF11577.3 ETN97374.1 - 0.84 9.4 5.7 0.79 9.5 0.1 2.6 2 1 0 2 2 2 0 NF-kappa-B essential modulator NEMO MMS19_N PF14500.1 ETN97375.1 - 0.0071 15.6 1.8 0.017 14.4 1.2 1.8 1 1 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.1 ETN97375.1 - 0.041 14.1 0.0 8.5 6.7 0.0 2.1 2 0 0 2 2 2 0 HEAT repeats Nup54 PF13874.1 ETN97375.1 - 0.05 13.2 1.2 0.096 12.3 0.1 1.8 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 MitMem_reg PF13012.1 ETN97375.1 - 2.6 8.1 7.1 6.7 6.8 1.4 2.2 1 1 0 2 2 2 0 Maintenance of mitochondrial structure and function G-alpha PF00503.15 ETN97376.1 - 4.1e-45 154.1 5.3 4.9e-45 153.8 3.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETN97376.1 - 3.1e-10 39.5 0.3 6.1e-10 38.6 0.2 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETN97376.1 - 0.00096 18.3 0.3 0.0011 18.1 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 ETN97376.1 - 0.002 17.3 0.1 0.0033 16.6 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 ETN97376.1 - 0.069 13.6 0.1 0.29 11.6 0.0 2.0 1 1 1 2 2 2 0 Miro-like protein Pox_polyA_pol_N PF12630.2 ETN97376.1 - 0.81 9.8 3.8 1.4 9.0 2.6 1.5 1 1 0 1 1 1 0 Poxvirus poly(A) polymerase N-terminal domain CN_hydrolase PF00795.17 ETN97377.1 - 1.7e-10 40.5 0.0 3.4e-09 36.3 0.0 2.2 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase CENP-B_dimeris PF09026.5 ETN97378.1 - 0.13 12.5 3.2 0.2 11.9 2.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Raftlin PF15250.1 ETN97378.1 - 0.51 8.8 6.0 0.62 8.5 4.1 1.1 1 0 0 1 1 1 0 Raftlin Hid1 PF12722.2 ETN97378.1 - 1.7 6.2 13.4 1.9 6.0 9.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Daxx PF03344.10 ETN97378.1 - 4.6 5.5 16.5 4.9 5.5 11.5 1.0 1 0 0 1 1 1 0 Daxx Family TPR_7 PF13176.1 ETN97379.1 - 0.0042 16.7 0.2 0.74 9.7 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETN97379.1 - 0.023 14.6 0.2 7.5 6.5 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF4227 PF14004.1 ETN97379.1 - 1.2 9.0 5.6 5.5 6.8 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4227) TPR_1 PF00515.23 ETN97379.1 - 1.9 8.2 5.0 7.9 6.2 0.6 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-CCHC_3 PF13917.1 ETN97380.1 - 3 7.6 16.6 1.4 8.6 4.3 2.4 1 1 1 2 2 2 0 Zinc knuckle Glyco_transf_11 PF01531.11 ETN97382.1 - 0.052 12.5 0.1 3.5 6.5 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 11 AAA_24 PF13479.1 ETN97383.1 - 0.00031 20.3 2.6 0.00036 20.1 0.6 1.7 1 1 1 2 2 2 1 AAA domain SH3BP5 PF05276.9 ETN97383.1 - 0.0076 15.5 7.1 0.0087 15.3 4.9 1.2 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) AbiH PF14253.1 ETN97383.1 - 0.051 13.1 6.2 0.019 14.5 1.4 1.7 1 1 1 2 2 2 0 Bacteriophage abortive infection AbiH DUF1400 PF07176.6 ETN97383.1 - 0.051 13.4 0.3 0.17 11.8 0.1 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) EMA PF02488.10 ETN97383.1 - 0.07 12.5 2.1 1.3 8.4 0.0 2.1 1 1 0 2 2 2 0 Merozoite Antigen Pantoate_ligase PF02569.10 ETN97383.1 - 0.081 11.6 0.5 0.1 11.3 0.3 1.2 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase Tap-RNA_bind PF09162.5 ETN97384.1 - 0.049 13.2 0.1 0.074 12.6 0.1 1.4 1 0 0 1 1 1 0 Tap, RNA-binding DUF3021 PF11457.3 ETN97384.1 - 0.22 11.4 7.4 0.27 11.1 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) Occludin_ELL PF07303.8 ETN97385.1 - 0.0047 17.6 2.3 0.0067 17.1 1.6 1.4 1 0 0 1 1 1 1 Occludin homology domain EFhand_Ca_insen PF08726.5 ETN97385.1 - 0.045 13.7 0.1 0.081 12.9 0.1 1.5 1 0 0 1 1 1 0 Ca2+ insensitive EF hand PUB PF09409.5 ETN97387.1 - 3.7e-05 23.4 1.0 0.00022 20.8 0.7 2.1 1 1 0 1 1 1 1 PUB domain WD40 PF00400.27 ETN97388.1 - 1.1e-58 193.0 36.5 6.2e-11 41.7 1.4 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETN97388.1 - 9.5e-10 37.2 10.3 0.0052 14.9 0.3 4.8 1 1 4 5 5 5 5 Nucleoporin Nup120/160 HAD PF12710.2 ETN97388.1 - 0.13 12.4 1.9 2.4 8.2 1.3 2.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Adaptin_binding PF10199.4 ETN97389.1 - 0.0063 16.7 10.3 0.0065 16.7 7.1 1.2 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 DUF1539 PF07560.6 ETN97389.1 - 0.007 16.2 0.9 0.011 15.6 0.1 1.7 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1539) DUF908 PF06012.7 ETN97389.1 - 0.016 14.5 2.7 0.016 14.5 1.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DDHD PF02862.12 ETN97389.1 - 0.037 13.8 9.5 0.05 13.3 6.6 1.3 1 1 0 1 1 1 0 DDHD domain RNase_H2_suC PF08615.6 ETN97389.1 - 0.056 13.2 7.5 0.22 11.3 5.1 2.0 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) AUX_IAA PF02309.11 ETN97389.1 - 0.062 13.0 6.7 0.078 12.7 4.7 1.3 1 0 0 1 1 1 0 AUX/IAA family Serinc PF03348.10 ETN97389.1 - 0.073 11.7 3.5 0.093 11.4 2.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Mitovir_RNA_pol PF05919.6 ETN97389.1 - 0.086 11.7 1.8 0.096 11.6 1.2 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase Anoctamin PF04547.7 ETN97389.1 - 0.35 9.4 4.4 0.44 9.1 3.1 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Hid1 PF12722.2 ETN97389.1 - 0.43 8.1 8.1 0.46 8.1 5.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Borrelia_P83 PF05262.6 ETN97389.1 - 0.47 8.6 11.0 0.49 8.6 7.6 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Folate_carrier PF01770.13 ETN97389.1 - 0.56 8.6 3.1 0.64 8.4 2.2 1.2 1 0 0 1 1 1 0 Reduced folate carrier BAF1_ABF1 PF04684.8 ETN97389.1 - 0.77 8.5 11.4 0.83 8.4 7.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Rhabdo_ncap PF00945.13 ETN97389.1 - 0.86 8.1 5.9 1.2 7.6 4.1 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein SRP_SPB PF02978.14 ETN97389.1 - 1 9.6 7.4 5.9 7.2 5.1 2.1 1 1 0 1 1 1 0 Signal peptide binding domain Bap31 PF05529.7 ETN97389.1 - 1.4 8.3 9.6 3 7.2 6.6 1.6 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like XAP5 PF04921.9 ETN97389.1 - 6.6 6.2 15.5 9.6 5.6 10.8 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator SopA PF13981.1 ETN97391.1 - 0.048 13.6 0.4 0.1 12.6 0.0 1.7 2 0 0 2 2 2 0 SopA-like central domain WD40 PF00400.27 ETN97392.1 - 8.8e-27 91.9 10.6 2.8e-10 39.6 0.6 4.5 4 1 1 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN97392.1 - 6.6e-05 21.2 0.8 0.06 11.4 0.1 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 WD40 PF00400.27 ETN97393.1 - 1.9e-45 151.1 9.6 1.1e-11 44.1 0.0 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETN97393.1 - 3.9e-08 31.8 0.3 0.077 11.1 0.0 3.6 1 1 1 3 3 3 3 Nucleoporin Nup120/160 DUF851 PF05867.6 ETN97393.1 - 0.026 13.7 0.0 0.15 11.2 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF851) Syntaxin-6_N PF09177.6 ETN97395.1 - 3.5 8.0 18.3 3.1 8.2 0.8 4.6 3 2 1 4 4 4 0 Syntaxin 6, N-terminal MCR_alpha_N PF02745.10 ETN97396.1 - 0.043 12.9 0.1 0.052 12.7 0.1 1.0 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, N-terminal domain DUF2597 PF10772.4 ETN97397.1 - 0.11 12.3 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2597) NACHT PF05729.7 ETN97398.1 - 0.00011 21.9 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 NACHT domain Torsin PF06309.6 ETN97398.1 - 0.02 14.7 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Torsin NB-ARC PF00931.17 ETN97398.1 - 0.04 12.7 0.0 0.057 12.2 0.0 1.3 1 1 0 1 1 1 0 NB-ARC domain DAP3 PF10236.4 ETN97398.1 - 0.063 12.1 0.0 0.087 11.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF2390 PF09523.5 ETN97399.1 - 0.15 12.2 0.2 6.9 6.8 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2390) CAP_GLY PF01302.20 ETN97400.1 - 1.3e-30 104.9 7.1 4.6e-13 48.6 0.2 3.1 3 0 0 3 3 3 3 CAP-Gly domain YajC PF02699.10 ETN97400.1 - 0.026 14.1 2.2 4.4 7.0 0.8 2.8 2 1 1 3 3 3 0 Preprotein translocase subunit CENP-B_dimeris PF09026.5 ETN97401.1 - 0.23 11.7 6.1 0.35 11.1 4.3 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.7 ETN97401.1 - 0.3 10.3 4.0 0.35 10.1 2.7 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.4 ETN97401.1 - 0.36 9.5 8.4 0.37 9.4 5.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) WD40 PF00400.27 ETN97402.1 - 4e-12 45.5 0.6 5.2e-09 35.6 0.2 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat zf-TRAF PF02176.13 ETN97404.1 - 0.0041 17.4 4.5 0.0041 17.4 3.1 3.3 2 1 0 3 3 3 1 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 ETN97404.1 - 0.049 13.6 1.0 0.6 10.1 0.7 2.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) GVQW PF13900.1 ETN97404.1 - 0.24 11.4 1.0 0.47 10.4 0.0 1.8 2 0 0 2 2 2 0 Putative binding domain ATG11 PF10377.4 ETN97404.1 - 0.63 9.9 4.2 0.79 9.6 2.7 1.4 1 1 0 1 1 1 0 Autophagy-related protein 11 TPR_12 PF13424.1 ETN97405.1 - 2e-154 501.8 26.6 1.5e-28 98.5 0.0 6.0 2 2 5 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.1 ETN97405.1 - 1.3e-84 275.9 0.0 1.8e-10 40.3 0.0 9.1 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_11 PF13414.1 ETN97405.1 - 4.1e-69 228.1 24.6 1.1e-17 63.4 0.3 5.3 4 1 1 5 5 5 5 TPR repeat TPR_1 PF00515.23 ETN97405.1 - 5.3e-68 222.0 58.9 1.2e-09 37.3 0.6 9.7 9 1 1 10 10 10 9 Tetratricopeptide repeat TPR_7 PF13176.1 ETN97405.1 - 5.9e-67 216.2 15.4 2.1e-08 33.3 0.0 9.2 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.12 ETN97405.1 - 2.1e-56 183.3 39.5 1.1e-07 31.2 0.9 9.9 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.1 ETN97405.1 - 2.7e-52 170.6 69.5 1e-07 31.1 0.7 9.3 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_17 PF13431.1 ETN97405.1 - 2.1e-37 124.2 20.0 0.00017 21.5 0.3 10.4 9 3 0 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.1 ETN97405.1 - 3.6e-29 100.7 0.0 7.5e-05 23.2 0.0 7.5 1 1 7 8 8 8 7 Tetratricopeptide repeat TPR_14 PF13428.1 ETN97405.1 - 1.2e-23 81.4 0.0 0.3 11.8 0.0 8.8 4 2 5 9 9 9 5 Tetratricopeptide repeat TPR_6 PF13174.1 ETN97405.1 - 1.2e-19 69.3 14.6 0.051 14.0 0.1 9.2 9 0 0 9 9 9 5 Tetratricopeptide repeat Apc3 PF12895.2 ETN97405.1 - 3.3e-19 68.7 24.4 4.6e-06 26.6 1.6 5.6 1 1 5 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.1 ETN97405.1 - 3.5e-17 62.4 12.6 5.7e-06 25.6 1.2 4.3 1 1 3 4 4 4 4 Soluble NSF attachment protein, SNAP TPR_19 PF14559.1 ETN97405.1 - 2.7e-15 56.4 5.5 0.0024 18.1 0.0 6.0 2 1 2 6 6 6 4 Tetratricopeptide repeat PPR PF01535.15 ETN97405.1 - 1.6e-13 49.6 26.6 0.28 11.2 0.0 9.4 9 0 0 9 9 9 4 PPR repeat MIT PF04212.13 ETN97405.1 - 6.6e-11 41.9 38.8 0.17 11.7 0.9 8.2 7 1 1 8 8 8 5 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.4 ETN97405.1 - 3.1e-10 39.1 6.2 4.6 6.5 0.0 9.5 11 0 0 11 11 10 0 SHNi-TPR TPR_3 PF07720.7 ETN97405.1 - 4.7e-10 39.0 44.9 0.00087 19.0 0.8 9.5 10 0 0 10 10 10 4 Tetratricopeptide repeat RPN7 PF10602.4 ETN97405.1 - 3.5e-07 29.7 22.8 0.5 9.7 0.1 7.1 2 2 4 7 7 7 2 26S proteasome subunit RPN7 Sel1 PF08238.7 ETN97405.1 - 7.6e-06 26.3 28.2 1.5 9.6 0.0 9.1 9 0 0 9 9 9 1 Sel1 repeat Musclin PF11037.3 ETN97405.1 - 0.00017 21.1 0.2 13 5.3 0.0 5.6 6 0 0 6 6 6 0 Insulin-resistance promoting peptide in skeletal muscle PPR_2 PF13041.1 ETN97405.1 - 0.00034 20.5 17.1 16 5.5 0.0 8.0 9 0 0 9 9 9 0 PPR repeat family TPR_9 PF13371.1 ETN97405.1 - 0.00035 20.3 0.0 19 5.1 0.0 5.1 2 1 6 8 8 8 0 Tetratricopeptide repeat Ten1_2 PF15490.1 ETN97405.1 - 0.00036 20.0 0.0 51 3.4 0.0 5.6 1 1 7 8 8 8 0 Telomere-capping, CST complex subunit DUF3568 PF12092.3 ETN97405.1 - 0.0008 19.1 1.7 11 5.7 0.0 5.1 2 2 4 6 6 6 0 Protein of unknown function (DUF3568) Syntaxin_2 PF14523.1 ETN97405.1 - 0.0024 17.8 0.1 5.1 7.1 0.0 4.7 5 2 1 6 6 4 0 Syntaxin-like protein HisG PF01634.13 ETN97405.1 - 0.0028 17.2 6.6 3.8 7.0 0.1 5.3 1 1 4 5 5 5 1 ATP phosphoribosyltransferase Rab5-bind PF09311.6 ETN97405.1 - 0.003 17.4 0.0 2.3 8.0 0.0 3.5 3 1 0 3 3 3 1 Rabaptin-like protein DUF627 PF04781.7 ETN97405.1 - 0.003 17.1 14.7 0.78 9.3 1.0 6.8 1 1 5 6 6 6 1 Protein of unknown function (DUF627) Pep3_Vps18 PF05131.9 ETN97405.1 - 0.0035 16.7 8.3 14 5.0 0.0 6.6 7 0 0 7 7 7 0 Pep3/Vps18/deep orange family DUF1268 PF06896.6 ETN97405.1 - 0.017 15.4 0.4 1.3e+02 2.9 0.0 5.2 5 2 2 7 7 5 0 Protein of unknown function (DUF1268) Mob_Pre PF01076.14 ETN97405.1 - 0.021 14.4 15.5 0.53 9.8 0.1 4.5 2 1 2 5 5 5 0 Plasmid recombination enzyme TPR_21 PF09976.4 ETN97405.1 - 0.03 14.2 10.6 0.076 12.9 0.0 5.3 7 0 0 7 7 6 0 Tetratricopeptide repeat Baculo_19 PF04798.7 ETN97405.1 - 0.05 12.9 7.5 4.6 6.6 0.0 4.3 3 1 2 5 5 5 0 Baculovirus 19 kDa protein conserved region FATC PF02260.15 ETN97405.1 - 0.095 12.1 12.8 40 3.7 0.1 6.1 7 0 0 7 7 6 0 FATC domain DUF357 PF04010.8 ETN97405.1 - 0.16 11.6 20.9 1.5 8.5 0.2 6.3 2 2 4 6 6 6 0 Protein of unknown function (DUF357) PG_binding_2 PF08823.6 ETN97405.1 - 0.62 10.1 6.7 2.3 8.3 0.1 4.2 4 2 1 5 5 3 0 Putative peptidoglycan binding domain Clathrin PF00637.15 ETN97405.1 - 3.6 7.1 20.7 14 5.2 0.7 6.8 2 1 2 5 5 5 0 Region in Clathrin and VPS FG-GAP PF01839.18 ETN97405.1 - 4.3 7.1 12.8 26 4.6 0.1 5.8 7 0 0 7 7 6 0 FG-GAP repeat DDE_3 PF13358.1 ETN97406.1 - 1.1e-25 90.0 0.3 2.3e-25 89.0 0.2 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 ETN97406.1 - 7.9e-14 51.4 12.7 1.2e-13 50.9 5.5 2.6 2 0 0 2 2 2 1 Transposase HTH_38 PF13936.1 ETN97406.1 - 5.1e-09 35.5 0.1 1.3e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.1 ETN97406.1 - 3.1e-05 24.0 4.1 5.1e-05 23.3 2.5 1.6 1 1 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_1 PF11427.3 ETN97406.1 - 0.00073 19.1 0.2 0.0018 17.8 0.1 1.8 2 0 0 2 2 2 1 Tc3 transposase HTH_30 PF13556.1 ETN97406.1 - 0.0038 16.7 1.5 0.023 14.2 0.0 2.6 2 1 1 3 3 3 1 PucR C-terminal helix-turn-helix domain Sigma70_r4_2 PF08281.7 ETN97406.1 - 0.01 15.3 1.2 0.055 12.9 0.2 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_28 PF13518.1 ETN97406.1 - 0.011 15.6 1.9 0.018 15.0 0.2 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.2 ETN97406.1 - 0.013 15.1 2.9 0.014 15.0 0.2 2.3 1 1 1 2 2 2 0 MarR family Succ_DH_flav_C PF02910.15 ETN97406.1 - 0.017 14.9 0.6 0.043 13.6 0.3 1.8 1 1 0 1 1 1 0 Fumarate reductase flavoprotein C-term HTH_23 PF13384.1 ETN97406.1 - 0.078 12.6 0.2 0.078 12.6 0.1 2.3 2 1 1 3 3 3 0 Homeodomain-like domain TrmB PF01978.14 ETN97406.1 - 0.083 12.6 0.1 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MarR PF01047.17 ETN97406.1 - 0.14 11.8 0.0 0.14 11.8 0.0 2.8 3 0 0 3 3 3 0 MarR family RGS PF00615.14 ETN97407.1 - 0.0052 16.8 0.5 0.006 16.6 0.3 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF1777 PF08648.7 ETN97408.1 - 0.00044 20.0 159.0 3.4e+02 0.8 38.8 3.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 ETN97408.1 - 0.55 8.6 87.9 0.13 10.6 31.9 2.0 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 MSC PF09402.5 ETN97409.1 - 1.2e-08 34.0 1.5 1.9e-05 23.5 1.1 2.3 1 1 0 1 1 1 1 Man1-Src1p-C-terminal domain UPF0233 PF06781.7 ETN97409.1 - 0.059 12.9 0.2 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) Exo_endo_phos_2 PF14529.1 ETN97410.1 - 5e-13 48.6 0.8 5e-13 48.6 0.6 2.1 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase TPR_12 PF13424.1 ETN97411.1 - 1.1e-29 102.2 1.3 1.4e-20 73.0 0.2 2.1 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETN97411.1 - 1.2e-22 78.4 11.3 9.4e-10 37.6 0.3 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETN97411.1 - 8.5e-22 75.1 1.1 3.1e-08 32.8 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETN97411.1 - 2.6e-20 71.6 0.0 1.8e-06 27.6 0.0 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETN97411.1 - 4e-18 63.7 20.2 3.5e-09 35.7 1.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETN97411.1 - 2.2e-17 61.5 4.8 1.5e-07 30.7 0.1 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETN97411.1 - 9.1e-17 60.4 6.5 1.5e-11 43.7 2.2 2.9 2 1 0 2 2 2 2 TPR repeat TPR_17 PF13431.1 ETN97411.1 - 3.7e-09 36.0 5.4 0.0062 16.6 0.0 3.9 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETN97411.1 - 4.2e-06 26.8 0.2 0.25 11.8 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETN97411.1 - 7.4e-06 26.1 0.0 0.47 11.2 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETN97411.1 - 1.4e-05 25.6 0.0 0.053 14.2 0.0 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETN97411.1 - 0.0016 17.6 0.1 2 7.7 0.0 2.8 3 0 0 3 3 3 2 SHNi-TPR TPR_3 PF07720.7 ETN97411.1 - 0.0019 17.9 3.5 7.5 6.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 ETN97411.1 - 0.0055 16.5 3.7 3 7.7 0.1 3.1 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 ETN97411.1 - 0.01 15.9 4.4 0.74 9.9 0.1 2.9 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.1 ETN97411.1 - 0.014 14.5 1.5 0.027 13.6 0.3 1.8 2 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP PPR PF01535.15 ETN97411.1 - 0.038 13.9 4.6 0.34 10.9 0.1 2.9 3 0 0 3 3 3 0 PPR repeat RE_LlaMI PF09562.5 ETN97411.1 - 0.045 12.9 1.4 0.057 12.5 0.6 1.3 1 1 0 1 1 1 0 LlaMI restriction endonuclease ATP-synt_E_2 PF08112.6 ETN97411.1 - 0.046 13.7 7.9 0.38 10.8 0.3 3.1 3 0 0 3 3 3 0 ATP synthase epsilon subunit DUF3713 PF12506.3 ETN97412.1 - 0.22 11.6 4.0 0.49 10.4 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3713) HEAT_2 PF13646.1 ETN97413.1 - 4e-20 71.8 0.1 1.8e-08 34.5 0.0 3.4 2 1 2 4 4 4 3 HEAT repeats HEAT PF02985.17 ETN97413.1 - 4.3e-10 38.8 0.0 0.0026 17.7 0.0 4.0 4 0 0 4 4 4 2 HEAT repeat TIP120 PF08623.5 ETN97413.1 - 7.2e-06 25.6 3.7 0.055 13.0 0.1 2.7 1 1 1 2 2 2 2 TATA-binding protein interacting (TIP20) Vac14_Fab1_bd PF12755.2 ETN97413.1 - 3e-05 24.3 0.1 0.068 13.5 0.1 2.9 1 1 2 3 3 3 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 ETN97413.1 - 9.3e-05 22.8 0.0 0.014 15.8 0.0 2.7 2 1 1 3 3 3 2 HEAT-like repeat DUF3554 PF12074.3 ETN97413.1 - 0.0011 18.5 1.1 0.035 13.5 0.1 2.5 1 1 2 3 3 3 2 Domain of unknown function (DUF3554) NLE PF08154.7 ETN97413.1 - 0.0091 15.9 7.2 2.4 8.2 0.1 4.7 5 0 0 5 5 5 1 NLE (NUC135) domain RNA_binding PF01877.12 ETN97413.1 - 0.1 12.5 3.8 0.11 12.4 0.1 2.9 3 0 0 3 3 3 0 RNA binding DUF2758 PF10957.3 ETN97413.1 - 0.2 11.5 3.6 8.9 6.2 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2758) Syntaphilin PF15290.1 ETN97413.1 - 0.86 9.0 4.8 2 7.8 1.2 2.7 1 1 1 2 2 2 0 Golgi-localised syntaxin-1-binding clamp Kelch_6 PF13964.1 ETN97414.1 - 3.6e-05 23.7 2.5 0.0048 17.0 0.0 4.1 4 1 1 5 5 5 1 Kelch motif Kelch_4 PF13418.1 ETN97414.1 - 4.1e-05 23.2 0.1 0.01 15.6 0.0 3.1 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETN97414.1 - 0.0028 17.1 0.6 0.021 14.3 0.1 2.7 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 ETN97414.1 - 0.0093 16.1 0.0 0.062 13.4 0.0 2.4 2 0 0 2 2 2 1 Galactose oxidase, central domain DUF733 PF05306.6 ETN97415.1 - 0.042 14.1 0.1 0.078 13.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF733) SET PF00856.23 ETN97416.1 - 6.9e-08 32.9 1.3 3.5e-06 27.4 0.0 2.7 2 1 0 2 2 2 1 SET domain DUF2852 PF11014.3 ETN97416.1 - 0.055 13.4 3.0 0.93 9.4 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) SR-25 PF10500.4 ETN97416.1 - 1.9 7.9 12.6 3.8 6.9 8.7 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ubiquitin PF00240.18 ETN97417.1 - 3.4e-122 397.9 16.6 1.2e-33 114.2 0.4 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 ETN97417.1 - 2.1e-73 242.0 13.7 3.2e-20 71.5 0.4 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 ETN97417.1 - 3.9e-22 78.3 7.4 4.2e-05 23.7 0.1 5.6 4 4 0 4 4 4 3 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 ETN97417.1 - 9.4e-16 57.6 1.4 0.028 14.2 0.0 4.8 4 3 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Telomere_Sde2 PF13019.1 ETN97417.1 - 2.4e-15 56.5 0.2 0.0031 17.2 0.0 3.8 4 0 0 4 4 4 3 Telomere stability and silencing DUF2407 PF10302.4 ETN97417.1 - 2.4e-12 46.8 1.0 0.13 12.4 0.0 4.2 1 1 3 4 4 4 3 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 ETN97417.1 - 4.8e-11 42.5 0.1 1.2 9.2 0.0 4.9 4 3 0 4 4 4 4 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 ETN97417.1 - 1.3e-08 34.6 3.9 0.21 11.5 0.0 3.6 4 0 0 4 4 4 3 GLUT4 regulating protein TUG USP7_C2 PF14533.1 ETN97417.1 - 3e-07 30.1 0.6 0.65 9.3 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin-specific protease C-terminal eRF1_1 PF03463.10 ETN97417.1 - 5e-07 29.3 1.4 1.1 8.8 0.0 4.3 1 1 3 4 4 4 3 eRF1 domain 1 PI3K_rbd PF00794.13 ETN97417.1 - 8.1e-06 25.7 1.1 3.4 7.6 0.0 3.4 3 0 0 3 3 3 3 PI3-kinase family, ras-binding domain FlgD_ig PF13860.1 ETN97417.1 - 0.00015 21.4 1.0 9.4 6.0 0.0 3.4 3 0 0 3 3 3 0 FlgD Ig-like domain IGR PF09597.5 ETN97417.1 - 0.00042 20.1 0.0 40 4.2 0.0 4.3 4 0 0 4 4 4 0 IGR protein motif GABP-alpha PF11620.3 ETN97417.1 - 0.0017 18.2 2.4 16 5.5 0.0 3.5 4 0 0 4 4 4 0 GA-binding protein alpha chain DUF3379 PF11859.3 ETN97417.1 - 0.002 17.3 2.1 11 5.1 0.0 3.5 2 1 0 4 4 4 0 Protein of unknown function (DUF3379) FERM_N PF09379.5 ETN97417.1 - 0.0054 16.7 6.8 18 5.4 0.1 5.1 4 3 0 4 4 4 0 FERM N-terminal domain CTDII PF01556.13 ETN97417.1 - 0.0064 16.3 10.3 3.5 7.6 0.2 3.2 1 1 2 3 3 3 3 DnaJ C terminal domain EMG1 PF03587.9 ETN97417.1 - 0.018 14.3 0.2 36 3.5 0.0 3.1 3 0 0 3 3 3 0 EMG1/NEP1 methyltransferase Plexin_cytopl PF08337.7 ETN97417.1 - 0.046 12.0 7.0 13 3.9 0.1 4.6 4 3 0 4 4 4 0 Plexin cytoplasmic RasGAP domain PI3K_p85B PF02192.11 ETN97417.1 - 0.52 9.7 2.3 92 2.5 0.0 3.3 3 0 0 3 3 3 0 PI3-kinase family, p85-binding domain CDK2AP PF09806.4 ETN97418.1 - 0.058 13.6 0.3 0.078 13.2 0.2 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Tom5 PF10642.4 ETN97418.1 - 0.36 10.5 3.7 0.8 9.4 2.6 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase TMEM51 PF15345.1 ETN97419.1 - 0.27 10.8 4.3 0.42 10.2 3.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 EAF PF09816.4 ETN97420.1 - 0.0025 17.7 0.2 0.0045 16.9 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor UCH PF00443.24 ETN97421.1 - 0.00083 18.5 1.8 0.00083 18.5 1.2 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Nudix_N_2 PF14803.1 ETN97421.1 - 0.11 12.2 0.2 0.11 12.2 0.1 2.1 2 0 0 2 2 2 0 Nudix N-terminal TPR_12 PF13424.1 ETN97422.1 - 3.5e-20 71.7 1.6 1.9e-09 37.3 0.2 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETN97422.1 - 5.3e-18 64.4 19.2 1.8e-11 43.4 2.3 3.1 1 1 3 4 4 4 3 TPR repeat TPR_8 PF13181.1 ETN97422.1 - 6.6e-15 53.7 17.4 4.7e-07 29.1 0.3 5.0 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETN97422.1 - 2.9e-13 48.6 11.4 9.7e-06 25.1 0.7 4.2 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETN97422.1 - 5.9e-13 47.5 1.3 0.00013 21.4 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETN97422.1 - 1.9e-12 46.2 19.4 1.1e-06 27.9 1.1 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETN97422.1 - 7.5e-10 38.4 0.0 0.00017 21.3 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.13 ETN97422.1 - 6.4e-06 25.9 7.4 0.025 14.4 0.0 3.5 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_17 PF13431.1 ETN97422.1 - 1.9e-05 24.4 0.5 0.23 11.7 0.0 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat DUF2225 PF09986.4 ETN97422.1 - 3.2e-05 23.4 2.0 0.00011 21.8 0.6 2.2 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_6 PF13174.1 ETN97422.1 - 7.1e-05 23.0 4.3 0.24 11.9 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETN97422.1 - 0.00015 22.0 0.1 0.95 10.2 0.0 2.8 3 0 0 3 3 2 2 Tetratricopeptide repeat Apc3 PF12895.2 ETN97422.1 - 0.00052 20.0 3.5 0.007 16.4 0.8 3.4 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 ETN97422.1 - 0.0011 19.6 0.0 0.89 10.3 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF2884 PF11101.3 ETN97422.1 - 0.0076 15.6 0.2 0.02 14.2 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2884) TPR_12 PF13424.1 ETN97423.1 - 3.1e-74 244.9 25.2 4.7e-22 77.7 1.2 4.3 1 1 2 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETN97423.1 - 4e-42 140.9 0.0 2.7e-08 33.4 0.0 5.9 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETN97423.1 - 8.6e-37 124.6 33.8 2.1e-14 52.8 3.7 3.9 1 1 2 4 4 4 4 TPR repeat TPR_7 PF13176.1 ETN97423.1 - 1e-35 118.7 16.1 2e-07 30.3 0.1 5.5 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_1 PF00515.23 ETN97423.1 - 6.5e-35 117.3 35.8 2.9e-09 36.1 0.8 5.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETN97423.1 - 3.3e-32 107.7 28.3 6.1e-08 31.9 0.4 5.5 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.1 ETN97423.1 - 1.1e-26 90.6 37.5 3.9e-07 29.3 1.8 5.4 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.1 ETN97423.1 - 1.3e-17 63.9 0.4 5.6e-05 23.6 0.0 4.3 3 2 1 4 4 4 4 Tetratricopeptide repeat TPR_6 PF13174.1 ETN97423.1 - 1.5e-15 56.5 7.8 0.0028 18.0 0.2 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETN97423.1 - 4.2e-15 54.6 5.5 0.27 11.5 0.0 6.0 5 1 0 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.1 ETN97423.1 - 4.2e-13 48.6 0.2 0.053 14.1 0.0 4.7 5 0 0 5 5 4 3 Tetratricopeptide repeat Apc3 PF12895.2 ETN97423.1 - 8.4e-10 38.6 13.2 1.8e-05 24.8 1.2 3.2 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETN97423.1 - 2.7e-08 34.0 4.8 0.00025 21.3 0.7 3.7 2 2 1 3 3 3 3 Tetratricopeptide repeat PPR PF01535.15 ETN97423.1 - 6.9e-07 28.8 9.6 0.51 10.4 0.1 5.3 5 0 0 5 5 5 2 PPR repeat ATP-synt_E_2 PF08112.6 ETN97423.1 - 0.0003 20.7 25.9 0.36 10.9 0.4 5.9 6 0 0 6 6 6 2 ATP synthase epsilon subunit DUF3883 PF13020.1 ETN97423.1 - 0.0019 17.9 7.9 0.3 10.8 0.6 3.6 1 1 3 4 4 4 1 Domain of unknown function (DUF3883) Ubiq-assoc PF09145.5 ETN97423.1 - 0.0028 17.4 11.6 14 5.6 0.2 6.0 5 1 0 6 6 5 0 Ubiquitin-associated DUF3416 PF11896.3 ETN97423.1 - 0.004 17.1 0.1 0.067 13.1 0.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF3416) Ten1_2 PF15490.1 ETN97423.1 - 0.0044 16.5 0.1 18 4.9 0.0 4.2 1 1 4 5 5 5 0 Telomere-capping, CST complex subunit Mob_Pre PF01076.14 ETN97423.1 - 0.0045 16.6 4.2 0.11 12.1 1.2 2.4 2 1 0 2 2 2 1 Plasmid recombination enzyme DUF2989 PF11207.3 ETN97423.1 - 0.0055 16.1 7.1 0.11 11.9 0.3 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF2989) TPR_21 PF09976.4 ETN97423.1 - 0.0097 15.8 5.2 0.9 9.4 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETN97423.1 - 0.017 14.3 7.1 3 7.1 0.0 4.8 6 0 0 6 6 5 0 SHNi-TPR IF-2 PF11987.3 ETN97423.1 - 0.022 14.6 0.1 1.1e+02 2.7 0.0 4.0 3 1 1 4 4 4 0 Translation-initiation factor 2 TPR_9 PF13371.1 ETN97423.1 - 0.027 14.3 0.1 1.2 9.0 0.0 3.1 2 2 0 2 2 2 0 Tetratricopeptide repeat Rapsyn_N PF10579.4 ETN97423.1 - 0.028 14.2 7.1 1.1 9.1 0.3 3.5 3 1 1 4 4 3 0 Rapsyn N-terminal myristoylation and linker region ANKH PF07260.6 ETN97423.1 - 0.081 11.9 1.2 36 3.2 0.0 3.2 1 1 2 3 3 3 0 Progressive ankylosis protein (ANKH) RPN7 PF10602.4 ETN97423.1 - 0.081 12.3 11.5 3 7.1 0.1 3.7 1 1 3 4 4 4 0 26S proteasome subunit RPN7 PYNP_C PF07831.8 ETN97423.1 - 0.095 12.1 1.8 24 4.4 0.0 3.4 3 0 0 3 3 3 0 Pyrimidine nucleoside phosphorylase C-terminal domain DUF3568 PF12092.3 ETN97423.1 - 0.099 12.3 1.2 14 5.4 0.0 3.9 1 1 4 5 5 5 0 Protein of unknown function (DUF3568) ATP-sulfurylase PF01747.12 ETN97423.1 - 0.1 11.9 1.3 12 5.1 0.0 2.8 2 2 1 3 3 3 0 ATP-sulfurylase Sel1 PF08238.7 ETN97423.1 - 0.13 12.8 17.8 4.1 8.1 0.2 5.1 5 0 0 5 5 5 0 Sel1 repeat SF3b10 PF07189.6 ETN97423.1 - 0.16 11.7 0.5 30 4.5 0.0 2.8 3 0 0 3 3 2 0 Splicing factor 3B subunit 10 (SF3b10) NSF PF02071.15 ETN97423.1 - 0.18 12.4 9.8 68 4.7 0.1 5.4 4 0 0 4 4 4 0 Aromatic-di-Alanine (AdAR) repeat PPR_2 PF13041.1 ETN97423.1 - 0.28 11.2 6.0 55 3.8 0.0 4.6 5 0 0 5 5 5 0 PPR repeat family Methyltransf_3 PF01596.12 ETN97423.1 - 0.65 9.0 8.8 23 3.9 1.8 3.6 1 1 3 4 4 4 0 O-methyltransferase MIT PF04212.13 ETN97423.1 - 1.8 8.5 20.0 4.3 7.2 0.4 5.0 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain HTH_Tnp_Tc3_2 PF01498.13 ETN97425.1 - 2.1e-11 43.7 1.1 2.8e-11 43.3 0.8 1.2 1 0 0 1 1 1 1 Transposase HTH_21 PF13276.1 ETN97425.1 - 0.00021 21.2 0.0 0.00045 20.1 0.0 1.6 1 0 0 1 1 1 1 HTH-like domain LacI PF00356.16 ETN97425.1 - 0.086 12.4 0.3 0.13 11.8 0.2 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family MIT PF04212.13 ETN97426.1 - 0.025 14.4 1.2 0.037 13.8 0.2 1.7 1 1 1 2 2 2 0 MIT (microtubule interacting and transport) domain Rota_NSP3 PF01665.11 ETN97426.1 - 0.035 13.0 8.1 0.038 12.9 5.6 1.0 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 Myb_DNA-bind_3 PF12776.2 ETN97426.1 - 0.078 13.6 1.6 0.094 13.3 1.1 1.1 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain PAS_6 PF08348.6 ETN97426.1 - 0.084 12.4 1.6 0.093 12.2 1.1 1.1 1 0 0 1 1 1 0 YheO-like PAS domain TPR_8 PF13181.1 ETN97426.1 - 0.16 11.7 6.2 1.5 8.7 0.1 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat CBP4 PF07960.6 ETN97426.1 - 0.22 11.1 4.4 0.22 11.1 3.0 1.1 1 0 0 1 1 1 0 CBP4 DUF896 PF05979.7 ETN97426.1 - 0.4 10.2 3.7 0.23 11.1 0.7 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF896) Dna2 PF08696.6 ETN97426.1 - 0.58 9.4 4.7 0.61 9.3 3.3 1.1 1 0 0 1 1 1 0 DNA replication factor Dna2 Apq12 PF12716.2 ETN97427.1 - 0.039 13.6 1.0 0.048 13.3 0.7 1.1 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis DUF1201 PF06716.6 ETN97427.1 - 0.33 10.7 4.0 0.44 10.4 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1201) TPR_12 PF13424.1 ETN97429.1 - 4.7e-41 138.6 4.0 1e-22 79.8 0.2 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETN97429.1 - 6.1e-24 83.4 14.3 2.7e-13 49.3 1.2 2.4 1 1 2 3 3 3 3 TPR repeat TPR_7 PF13176.1 ETN97429.1 - 2.2e-17 61.3 0.5 4.1e-09 35.5 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETN97429.1 - 7.5e-16 57.4 0.1 5.4e-08 32.5 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETN97429.1 - 8e-15 53.7 14.8 5.2e-09 35.3 0.7 4.7 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETN97429.1 - 6.6e-13 47.5 7.1 6e-07 28.8 0.2 3.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETN97429.1 - 1.4e-08 33.8 15.3 2.3e-06 26.9 1.9 3.6 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETN97429.1 - 2e-07 30.6 5.4 0.0028 17.7 0.1 3.8 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETN97429.1 - 1.1e-06 29.1 0.0 7.1e-05 23.3 0.0 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETN97429.1 - 6.9e-06 26.1 0.2 0.15 12.5 0.0 2.7 3 0 0 3 3 2 2 Tetratricopeptide repeat SNAP PF14938.1 ETN97429.1 - 3.3e-05 23.1 0.0 3.9e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP MIT PF04212.13 ETN97429.1 - 0.00024 20.9 3.3 0.19 11.6 0.1 2.5 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain Sel1 PF08238.7 ETN97429.1 - 0.0011 19.5 0.9 4.1 8.1 0.2 3.1 3 0 0 3 3 3 2 Sel1 repeat Apc3 PF12895.2 ETN97429.1 - 0.0011 19.0 0.8 0.0026 17.8 0.6 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 ETN97429.1 - 0.0016 18.1 5.3 0.35 10.7 0.3 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETN97429.1 - 0.0022 18.4 0.0 0.94 10.2 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat PPR PF01535.15 ETN97429.1 - 0.0037 17.1 0.5 0.16 12.0 0.1 2.6 2 0 0 2 2 2 1 PPR repeat TPR_19 PF14559.1 ETN97429.1 - 0.01 16.1 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat BING4CT PF08149.6 ETN97429.1 - 0.073 12.5 0.0 1 8.9 0.0 2.2 2 1 0 2 2 2 0 BING4CT (NUC141) domain Ten1_2 PF15490.1 ETN97429.1 - 0.075 12.6 0.0 20 4.7 0.0 2.9 1 1 2 3 3 3 0 Telomere-capping, CST complex subunit DUF3568 PF12092.3 ETN97429.1 - 0.088 12.5 0.0 3.1 7.5 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3568) ATP-synt_E_2 PF08112.6 ETN97429.1 - 0.15 12.1 4.8 2.4 8.2 3.3 2.5 1 1 0 1 1 1 0 ATP synthase epsilon subunit LPP PF04728.8 ETN97430.1 - 0.024 14.4 0.5 0.038 13.8 0.4 1.4 1 0 0 1 1 1 0 Lipoprotein leucine-zipper BAP PF06639.6 ETN97430.1 - 0.094 12.4 0.4 0.094 12.4 0.3 1.6 2 0 0 2 2 2 0 Basal layer antifungal peptide (BAP) BRICHOS PF04089.9 ETN97430.1 - 0.18 11.7 3.4 4.1 7.3 0.5 2.1 2 0 0 2 2 2 0 BRICHOS domain ApoL PF05461.6 ETN97430.1 - 0.23 10.6 4.0 0.28 10.3 2.8 1.0 1 0 0 1 1 1 0 Apolipoprotein L CAP_GLY PF01302.20 ETN97431.1 - 0.015 15.0 0.2 6.8 6.4 0.0 3.1 3 1 1 4 4 4 0 CAP-Gly domain TAFII55_N PF04658.8 ETN97432.1 - 1.5e-23 83.1 0.0 2.4e-23 82.4 0.0 1.4 1 1 0 1 1 1 1 TAFII55 protein conserved region Arc PF03869.9 ETN97432.1 - 0.017 14.7 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Arc-like DNA binding domain DUF3439 PF11921.3 ETN97432.1 - 0.18 11.5 6.7 0.3 10.8 4.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Crl PF07417.7 ETN97434.1 - 0.058 13.1 0.2 0.058 13.1 0.1 1.8 2 0 0 2 2 2 0 Transcriptional regulator Crl CAP_GLY PF01302.20 ETN97436.1 - 2.7e-08 33.3 0.0 4.3e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain DUF1212 PF06738.7 ETN97436.1 - 1.4 8.3 7.0 8.5 5.7 3.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) Utp14 PF04615.8 ETN97439.1 - 1.1 7.3 31.2 1.3 7.1 21.6 1.0 1 0 0 1 1 1 0 Utp14 protein MIP-T3 PF10243.4 ETN97439.1 - 5.7 5.2 30.0 7.1 4.9 20.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF3832 PF12909.2 ETN97442.1 - 0.082 12.9 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3832) zf-TRAF PF02176.13 ETN97443.1 - 2.1e-05 24.8 3.2 2.1e-05 24.8 2.2 3.1 3 1 0 3 3 3 1 TRAF-type zinc finger zf-H2C2_5 PF13909.1 ETN97443.1 - 0.42 10.9 6.4 12 6.3 2.2 3.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain CAP_GLY PF01302.20 ETN97445.1 - 0.017 14.7 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 CAP-Gly domain Sec62 PF03839.11 ETN97448.1 - 0.36 10.1 4.5 1 8.7 3.1 1.7 1 0 0 1 1 1 0 Translocation protein Sec62 Tmemb_9 PF05434.6 ETN97448.1 - 2.4 7.8 11.1 0.4 10.4 2.9 3.0 3 0 0 3 3 3 0 TMEM9 Rifin_STEVOR PF02009.11 ETN97448.1 - 6.9 6.2 13.4 18 4.8 9.3 1.6 1 0 0 1 1 1 0 Rifin/stevor family Pombe_5TM PF09437.5 ETN97449.1 - 0.045 13.1 1.0 0.05 13.0 0.7 1.0 1 0 0 1 1 1 0 Pombe specific 5TM protein NVEALA PF14055.1 ETN97449.1 - 0.16 11.7 1.0 0.25 11.0 0.7 1.3 1 0 0 1 1 1 0 NVEALA protein UL2 PF08196.6 ETN97450.1 - 0.0045 16.6 1.1 0.009 15.7 0.3 1.8 2 0 0 2 2 2 1 UL2 protein DUF3844 PF12955.2 ETN97450.1 - 0.0094 16.0 0.3 0.0094 16.0 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3844) HupE_UreJ PF04955.7 ETN97450.1 - 0.6 9.3 5.8 0.74 9.0 0.2 2.1 2 0 0 2 2 2 0 HupE / UreJ protein WD40 PF00400.27 ETN97451.1 - 3.2e-29 99.6 0.1 4.5e-15 54.8 0.0 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat PQQ_2 PF13360.1 ETN97451.1 - 0.01 15.3 0.1 0.016 14.6 0.1 1.4 1 1 0 1 1 1 1 PQQ-like domain PD40 PF07676.7 ETN97451.1 - 0.028 14.0 0.2 8.5 6.1 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 ETN97451.1 - 0.073 12.4 0.3 13 5.1 0.0 2.5 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature DCP1 PF06058.8 ETN97452.1 - 0.0058 16.6 1.7 2.1 8.4 0.0 3.0 3 0 0 3 3 3 2 Dcp1-like decapping family EF-hand_6 PF13405.1 ETN97452.1 - 0.066 13.1 2.3 0.27 11.2 1.6 2.1 1 1 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.27 ETN97452.1 - 0.068 12.5 3.4 0.092 12.0 1.1 2.3 2 1 0 2 2 2 0 EF hand EF-hand_5 PF13202.1 ETN97452.1 - 0.25 10.7 3.9 0.18 11.2 1.1 2.0 2 0 0 2 2 2 0 EF hand Kin17_mid PF10357.4 ETN97453.1 - 0.023 14.3 1.9 0.089 12.4 1.3 1.8 1 1 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein HNH_3 PF13392.1 ETN97453.1 - 0.1 11.9 0.1 0.22 10.9 0.1 1.5 1 0 0 1 1 1 0 HNH endonuclease GRAB PF10375.4 ETN97453.1 - 0.73 9.6 3.3 15 5.5 0.9 2.5 2 0 0 2 2 2 0 GRIP-related Arf-binding domain Cnd1 PF12717.2 ETN97455.1 - 0.0001 22.1 3.7 0.0078 16.0 0.2 2.4 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 DUF2713 PF10897.3 ETN97455.1 - 0.008 15.4 0.2 0.014 14.6 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2713) TAN PF11640.3 ETN97455.1 - 0.0092 15.7 4.5 0.3 10.8 0.1 4.0 1 1 3 4 4 4 1 Telomere-length maintenance and DNA damage repair HEAT PF02985.17 ETN97455.1 - 0.02 14.9 0.0 72 3.8 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat DUF3596 PF12167.3 ETN97455.1 - 0.092 12.2 0.2 2.4 7.7 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3596) HEAT_EZ PF13513.1 ETN97455.1 - 0.13 12.7 0.0 1.2 9.7 0.0 2.5 3 0 0 3 3 3 0 HEAT-like repeat Zn_Tnp_IS1595 PF12760.2 ETN97456.1 - 1.7e-11 43.7 4.7 2.6e-11 43.1 3.3 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DDE_Tnp_IS1595 PF12762.2 ETN97456.1 - 4.1e-10 39.6 0.6 6.5e-10 39.0 0.4 1.3 1 0 0 1 1 1 1 ISXO2-like transposase domain CpXC PF14353.1 ETN97456.1 - 0.02 14.8 0.4 0.057 13.3 0.3 1.8 1 1 1 2 2 2 0 CpXC protein Peptidase_C26 PF07722.8 ETN97457.1 - 3.9e-40 137.6 0.0 4.5e-40 137.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase C26 GATase PF00117.23 ETN97457.1 - 6e-08 32.3 0.1 1.7e-07 30.9 0.1 1.7 1 1 0 2 2 2 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 ETN97457.1 - 0.022 14.3 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain PEPCK_ATP PF01293.15 ETN97458.1 - 2.3e-170 567.1 0.0 3.1e-170 566.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.1 ETN97458.1 - 0.01 15.8 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 ETN97458.1 - 0.18 11.3 0.4 0.38 10.3 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RRM_1 PF00076.17 ETN97459.1 - 5e-18 64.5 0.1 1.6e-17 62.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETN97459.1 - 2.8e-15 56.0 0.0 8.5e-15 54.4 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETN97459.1 - 9.5e-07 28.5 0.0 1.8e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2704 PF10866.3 ETN97460.1 - 0.049 13.0 3.1 0.11 11.8 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2704) BLVR PF06375.6 ETN97461.1 - 5.5 6.8 16.2 2 8.2 0.5 2.1 1 1 1 2 2 2 0 Bovine leukaemia virus receptor (BLVR) DUF445 PF04286.7 ETN97464.1 - 0.079 12.4 5.5 0.1 12.1 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) CBP4 PF07960.6 ETN97464.1 - 0.1 12.2 2.8 0.25 10.9 2.0 1.7 1 0 0 1 1 1 0 CBP4 cNMP_binding PF00027.24 ETN97465.1 - 9e-16 57.4 0.5 5.4e-09 35.7 0.0 2.4 1 1 1 2 2 2 2 Cyclic nucleotide-binding domain Nop25 PF09805.4 ETN97465.1 - 1.6 8.8 6.0 2.4 8.2 4.1 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Secretin_N_2 PF07655.8 ETN97465.1 - 1.7 9.1 12.8 3.1 8.2 8.9 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain LRR_4 PF12799.2 ETN97466.1 - 1.3e-11 43.8 21.4 2.3e-07 30.2 2.3 3.8 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETN97466.1 - 3.2e-10 39.6 29.5 9.8e-06 25.2 2.3 3.3 2 1 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 ETN97466.1 - 1e-07 30.9 18.5 0.025 14.5 0.2 5.7 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_7 PF13504.1 ETN97466.1 - 0.003 17.4 12.6 3.4 8.2 0.2 4.7 4 0 0 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 ETN97466.1 - 0.0057 16.5 14.2 0.45 10.7 0.1 4.6 5 0 0 5 5 5 2 Leucine Rich repeat Peptidase_C14 PF00656.17 ETN97467.1 - 2.7e-06 27.2 0.4 4.2e-06 26.6 0.3 1.3 1 1 0 1 1 1 1 Caspase domain MT-A70 PF05063.9 ETN97467.1 - 0.075 12.5 0.1 0.15 11.5 0.1 1.4 1 1 0 1 1 1 0 MT-A70 UPF0180 PF03698.8 ETN97468.1 - 0.0014 18.3 0.1 0.0021 17.8 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0180) DUF3641 PF12345.3 ETN97468.1 - 0.04 13.7 0.7 0.053 13.3 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3641) PRE_C2HC PF07530.6 ETN97468.1 - 0.095 12.6 2.1 0.096 12.5 0.4 1.9 2 1 0 2 2 2 0 Associated with zinc fingers NEP PF10167.4 ETN97468.1 - 0.1 12.3 2.5 0.12 12.0 1.4 1.5 1 1 0 1 1 1 0 Uncharacterised conserved protein Arg_repressor PF01316.16 ETN97468.1 - 0.12 11.9 1.5 2.3 7.8 0.3 2.5 2 1 0 2 2 2 0 Arginine repressor, DNA binding domain DUF3866 PF12982.2 ETN97468.1 - 0.14 11.0 0.2 0.15 10.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3866) Nucleoporin_N PF08801.6 ETN97469.1 - 0.0031 16.3 1.1 0.0034 16.2 0.8 1.0 1 0 0 1 1 1 1 Nup133 N terminal like DUF1877 PF08974.5 ETN97469.1 - 0.079 12.6 1.3 0.11 12.1 0.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1877) DUF1451 PF07295.6 ETN97469.1 - 0.26 11.0 1.2 17 5.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1451) DUF445 PF04286.7 ETN97469.1 - 0.41 10.1 4.6 0.48 9.9 3.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Prefoldin PF02996.12 ETN97469.1 - 0.77 9.4 4.9 7 6.3 0.2 2.2 2 0 0 2 2 2 0 Prefoldin subunit TK PF00265.13 ETN97471.1 - 0.037 13.5 0.2 0.072 12.6 0.0 1.6 2 0 0 2 2 2 0 Thymidine kinase HYR PF02494.11 ETN97472.1 - 0.0035 17.3 0.3 0.0078 16.2 0.2 1.6 1 0 0 1 1 1 1 HYR domain PT PF04886.7 ETN97472.1 - 0.63 9.4 23.8 1.8 7.9 4.9 2.4 2 0 0 2 2 2 0 PT repeat SICA_alpha PF12887.2 ETN97473.1 - 0.0081 15.9 0.1 0.01 15.6 0.1 1.1 1 0 0 1 1 1 1 SICA extracellular alpha domain WD40 PF00400.27 ETN97475.1 - 6.4e-12 44.8 0.1 2.2e-08 33.6 0.0 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETN97475.1 - 0.0097 14.0 0.2 0.045 11.8 0.0 1.8 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETN97475.1 - 0.064 12.7 0.1 0.067 12.6 0.1 1.0 1 0 0 1 1 1 0 PQQ-like domain MIP-T3 PF10243.4 ETN97476.1 - 0.012 14.1 32.0 0.016 13.7 22.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ycf1 PF05758.7 ETN97476.1 - 3.2 5.3 15.5 3.5 5.2 10.7 1.3 1 0 0 1 1 1 0 Ycf1 Imm6 PF14434.1 ETN97478.1 - 0.027 14.1 2.7 0.031 13.9 1.9 1.3 1 0 0 1 1 1 0 Immunity protein Imm6 HTH_12 PF08461.5 ETN97478.1 - 0.063 13.0 0.1 0.12 12.1 0.0 1.5 1 1 0 1 1 1 0 Ribonuclease R winged-helix domain priB_priC PF07445.7 ETN97478.1 - 0.19 11.2 6.0 0.21 11.0 4.2 1.1 1 0 0 1 1 1 0 Primosomal replication protein priB and priC Peptidase_M27 PF01742.12 ETN97478.1 - 0.44 9.3 9.2 0.47 9.2 6.4 1.1 1 0 0 1 1 1 0 Clostridial neurotoxin zinc protease CKAP2_C PF15297.1 ETN97478.1 - 1.7 7.3 13.6 1.8 7.3 9.4 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus PcfK PF14058.1 ETN97478.1 - 5 7.2 14.0 2.2 8.4 8.1 1.5 1 1 0 1 1 1 0 PcfK-like protein DUF904 PF06005.7 ETN97478.1 - 5.8 7.2 12.3 7.6 6.8 8.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF106 PF01956.11 ETN97478.1 - 7.2 6.1 7.3 8.5 5.8 5.1 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 Exo_endo_phos PF03372.18 ETN97479.1 - 0.00075 19.4 0.0 0.00097 19.1 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LacI PF00356.16 ETN97481.1 - 0.028 14.0 0.1 0.073 12.6 0.1 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family Kelch_6 PF13964.1 ETN97482.1 - 0.016 15.3 0.1 7.8 6.8 0.0 2.8 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.1 ETN97482.1 - 0.035 13.8 0.2 1.5 8.6 0.0 2.7 1 1 1 2 2 2 0 Galactose oxidase, central domain RNase_H PF00075.19 ETN97484.1 - 0.089 13.1 0.0 2 8.7 0.0 2.3 2 0 0 2 2 2 0 RNase H OmpA PF00691.15 ETN97485.1 - 0.095 13.1 2.6 0.13 12.6 1.7 1.5 1 1 0 1 1 1 0 OmpA family Sec66 PF09802.4 ETN97486.1 - 0.0029 17.0 0.8 0.0029 17.0 0.5 1.8 2 1 0 2 2 2 1 Preprotein translocase subunit Sec66 Anticodon_1 PF08264.8 ETN97486.1 - 0.018 14.8 0.5 0.1 12.3 0.0 2.3 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA RGCC PF15151.1 ETN97486.1 - 0.059 13.7 0.7 0.82 10.1 0.1 2.5 2 0 0 2 2 2 0 Response gene to complement 32 protein family DUF4570 PF15134.1 ETN97486.1 - 0.56 10.0 6.4 1 9.2 1.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4570) DMPK_coil PF08826.5 ETN97486.1 - 3.9 7.4 7.7 1.3 9.0 0.1 3.1 2 1 1 3 3 3 0 DMPK coiled coil domain like Raptor_N PF14538.1 ETN97487.1 - 0.1 12.4 0.3 0.29 10.9 0.1 1.8 1 1 0 1 1 1 0 Raptor N-terminal CASPase like domain DMPK_coil PF08826.5 ETN97487.1 - 0.16 11.9 6.1 1.8 8.5 0.5 2.8 2 0 0 2 2 2 0 DMPK coiled coil domain like Metallophos PF00149.23 ETN97488.1 - 0.0015 18.0 0.1 0.0019 17.6 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ank_5 PF13857.1 ETN97489.1 - 0.00073 19.7 0.5 0.0023 18.0 0.4 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 ETN97489.1 - 0.0009 18.9 0.1 0.0026 17.4 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat DUF3718 PF12514.3 ETN97489.1 - 0.0045 17.0 0.0 0.012 15.6 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3718) Ank_2 PF12796.2 ETN97489.1 - 0.016 15.5 0.1 0.041 14.2 0.1 1.7 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) DUF3800 PF12686.2 ETN97489.1 - 0.031 13.9 0.5 0.062 12.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3800) Ank_3 PF13606.1 ETN97489.1 - 0.037 14.2 0.5 0.28 11.5 0.1 2.6 2 0 0 2 2 2 0 Ankyrin repeat ClpB_D2-small PF10431.4 ETN97490.1 - 0.055 13.3 0.0 4.2 7.3 0.0 2.2 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein DUF603 PF04645.7 ETN97491.1 - 0.012 15.5 1.6 0.016 15.1 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF603 DUF502 PF04367.8 ETN97491.1 - 0.038 13.7 0.1 0.093 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF502) Tektin PF03148.9 ETN97492.1 - 0.13 10.7 0.1 0.15 10.5 0.1 1.0 1 0 0 1 1 1 0 Tektin family PerC PF06069.6 ETN97494.1 - 0.11 12.5 0.1 0.32 11.0 0.0 1.7 2 0 0 2 2 2 0 PerC transcriptional activator Ribosomal_L39 PF00832.15 ETN97494.1 - 0.23 10.9 1.4 0.36 10.3 0.1 2.0 2 0 0 2 2 2 0 Ribosomal L39 protein Salp15 PF12115.3 ETN97495.1 - 0.16 12.2 3.4 0.21 11.8 2.4 1.2 1 0 0 1 1 1 0 Salivary protein of 15kDa inhibits CD4+ T cell activation Colicin_D PF11429.3 ETN97498.1 - 0.12 12.5 4.2 0.1 12.7 1.5 1.9 2 1 0 2 2 2 0 Colicin D DUF2415 PF10313.4 ETN97499.1 - 0.0018 17.9 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) FA_desaturase PF00487.19 ETN97500.1 - 0.022 14.2 0.1 0.027 13.9 0.1 1.2 1 0 0 1 1 1 0 Fatty acid desaturase Receptor_2B4 PF11465.3 ETN97500.1 - 0.12 12.2 0.3 0.34 10.8 0.1 1.7 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 Kelch_4 PF13418.1 ETN97501.1 - 0.0019 17.9 0.1 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETN97501.1 - 0.0089 16.1 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 Kelch motif Kelch_1 PF01344.20 ETN97501.1 - 0.01 15.3 0.1 0.02 14.4 0.1 1.4 1 0 0 1 1 1 0 Kelch motif Kelch_3 PF13415.1 ETN97501.1 - 0.018 15.1 0.1 0.05 13.7 0.1 1.7 1 0 0 1 1 1 0 Galactose oxidase, central domain Mucin PF01456.12 ETN97501.1 - 0.043 13.5 16.4 0.067 12.9 11.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3316 PF11777.3 ETN97501.1 - 0.21 11.3 4.1 0.28 10.9 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3316) BTB PF00651.26 ETN97502.1 - 1.1e-14 54.3 0.1 1.7e-14 53.7 0.1 1.3 1 1 0 1 1 1 1 BTB/POZ domain DRIM PF07539.7 ETN97502.1 - 0.017 14.5 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Down-regulated in metastasis DUF2451 PF10474.4 ETN97503.1 - 0.00089 19.0 0.5 0.0015 18.3 0.2 1.3 1 1 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) YycI PF09648.5 ETN97503.1 - 0.014 14.8 2.8 0.017 14.5 1.9 1.1 1 0 0 1 1 1 0 YycH protein LRR_5 PF13306.1 ETN97503.1 - 0.11 12.1 5.2 0.15 11.7 3.6 1.2 1 0 0 1 1 1 0 Leucine rich repeats (6 copies) DUF1043 PF06295.7 ETN97503.1 - 0.18 11.4 1.5 0.21 11.2 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF241 PF03087.9 ETN97508.1 - 0.077 12.4 3.2 0.079 12.4 0.3 2.1 1 1 1 2 2 2 0 Arabidopsis protein of unknown function HRM PF02793.17 ETN97508.1 - 0.087 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Hormone receptor domain Peptidase_C14 PF00656.17 ETN97509.1 - 5.6e-06 26.2 0.1 7.7e-06 25.7 0.1 1.1 1 0 0 1 1 1 1 Caspase domain DCP2 PF05026.8 ETN97509.1 - 0.062 13.2 0.1 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 Dcp2, box A domain WD40 PF00400.27 ETN97510.1 - 1.8e-09 37.0 2.2 3.7e-09 36.0 1.1 1.8 2 0 0 2 2 2 1 WD domain, G-beta repeat ABC_membrane_3 PF13748.1 ETN97510.1 - 0.13 11.3 0.4 0.16 11.0 0.3 1.1 1 0 0 1 1 1 0 ABC transporter transmembrane region Tubulin_C PF03953.12 ETN97511.1 - 1.6e-13 50.7 0.0 2.6e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 ETN97511.1 - 0.058 13.2 0.2 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain DUF4475 PF14753.1 ETN97512.1 - 0.0017 17.9 1.0 0.0022 17.5 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4475) DUF1850 PF08905.6 ETN97513.1 - 0.0016 18.2 1.1 0.0031 17.2 0.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1850) UBA PF00627.26 ETN97513.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain CAP_GLY PF01302.20 ETN97515.1 - 1.1e-32 111.5 3.1 1.1e-18 66.6 0.1 2.3 2 0 0 2 2 2 2 CAP-Gly domain BACK PF07707.10 ETN97515.1 - 2.7e-07 30.3 0.2 9.1e-05 22.2 0.1 2.6 2 0 0 2 2 2 2 BTB And C-terminal Kelch Spore_coat_CotO PF14153.1 ETN97515.1 - 0.031 13.7 0.4 0.031 13.7 0.2 4.4 3 1 0 3 3 3 0 Spore coat protein CotO DUF3573 PF12097.3 ETN97515.1 - 6.9 5.1 10.2 0.049 12.2 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) SAM_2 PF07647.12 ETN97516.1 - 0.075 12.8 0.1 7 6.5 0.0 2.9 2 1 0 2 2 2 0 SAM domain (Sterile alpha motif) Myotub-related PF06602.9 ETN97517.1 - 2e-27 95.9 4.6 7.4e-19 67.7 0.0 3.0 2 1 0 3 3 3 3 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 ETN97517.1 - 0.056 13.6 0.3 0.13 12.4 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family Utp14 PF04615.8 ETN97518.1 - 0.6 8.2 23.6 0.67 8.0 16.4 1.0 1 0 0 1 1 1 0 Utp14 protein Gag_spuma PF03276.9 ETN97518.1 - 9.6 4.4 12.8 14 3.8 8.9 1.2 1 0 0 1 1 1 0 Spumavirus gag protein TFIIA PF03153.8 ETN97521.1 - 0.0024 17.8 4.1 0.0024 17.8 2.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Tim54 PF11711.3 ETN97521.1 - 0.099 11.2 2.9 0.11 11.1 2.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 VID27 PF08553.5 ETN97521.1 - 0.17 10.0 12.9 0.2 9.8 8.9 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Zip PF02535.17 ETN97521.1 - 0.25 10.2 1.6 0.26 10.2 1.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter GOLD_2 PF13897.1 ETN97521.1 - 1.5 9.0 4.9 2.5 8.3 3.4 1.4 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking RNA_pol_Rpc4 PF05132.9 ETN97521.1 - 1.8 8.5 8.9 1.5 8.8 5.1 1.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 CobT PF06213.7 ETN97521.1 - 3 6.9 15.7 3.7 6.6 10.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.9 ETN97521.1 - 5.8 4.8 17.8 7.1 4.5 12.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleoside_tran PF01733.13 ETN97523.1 - 0.018 14.1 2.6 0.023 13.8 1.8 1.3 1 0 0 1 1 1 0 Nucleoside transporter Glyco_transf_92 PF01697.22 ETN97523.1 - 0.043 13.1 5.3 0.058 12.7 3.7 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 92 ATPgrasp_TupA PF14305.1 ETN97523.1 - 0.059 12.6 8.6 0.04 13.2 4.6 1.7 1 1 1 2 2 2 0 TupA-like ATPgrasp DUF106 PF01956.11 ETN97523.1 - 0.071 12.6 1.4 0.09 12.3 1.0 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF106 AAA_11 PF13086.1 ETN97523.1 - 0.11 12.1 4.4 0.12 11.9 3.1 1.1 1 0 0 1 1 1 0 AAA domain AlaDh_PNT_C PF01262.16 ETN97523.1 - 0.14 11.7 1.7 0.2 11.2 1.2 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF262 PF03235.9 ETN97523.1 - 0.16 11.9 8.4 0.17 11.8 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 RNA_pol_Rpb1_5 PF04998.12 ETN97523.1 - 1.8 7.7 6.2 2.1 7.5 4.3 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF641 PF04859.7 ETN97524.1 - 0.031 14.0 4.4 0.095 12.4 3.1 1.9 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Haemocyan_bet_s PF14830.1 ETN97524.1 - 0.087 12.5 0.3 0.14 11.8 0.1 1.5 1 1 0 1 1 1 0 Haemocyanin beta-sandwich Atg14 PF10186.4 ETN97524.1 - 0.11 11.3 5.1 0.15 11.0 3.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 ETN97524.1 - 0.19 10.3 11.0 0.22 10.1 7.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2968 PF11180.3 ETN97524.1 - 0.35 10.2 3.0 0.46 9.8 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Syntaphilin PF15290.1 ETN97524.1 - 0.5 9.7 7.3 0.64 9.4 5.1 1.3 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Herpes_BLRF2 PF05812.7 ETN97524.1 - 0.57 9.9 7.2 1.3 8.8 5.0 1.6 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein DivIC PF04977.10 ETN97524.1 - 1.2 8.6 0.0 1.2 8.6 0.0 3.1 3 1 0 3 3 3 0 Septum formation initiator DUF1640 PF07798.6 ETN97524.1 - 4.8 7.1 16.3 8.8 6.3 6.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) Bunya_RdRp PF04196.7 ETN97525.1 - 0.11 10.4 3.6 0.12 10.4 2.5 1.1 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase Sua5_yciO_yrdC PF01300.13 ETN97525.1 - 0.3 10.3 2.4 0.35 10.1 1.7 1.1 1 0 0 1 1 1 0 Telomere recombination Peptidase_S49_N PF08496.5 ETN97525.1 - 3.5 7.4 7.9 4.3 7.1 5.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal BLVR PF06375.6 ETN97527.1 - 0.26 11.1 7.2 0.13 12.1 1.6 2.0 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Bud13 PF09736.4 ETN97527.1 - 2.2 8.5 8.1 4.1 7.6 1.1 2.0 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex ABA_GPCR PF12430.3 ETN97528.1 - 0.069 12.2 0.1 0.088 11.9 0.0 1.2 1 0 0 1 1 1 0 Abscisic acid G-protein coupled receptor Pkinase PF00069.20 ETN97529.1 - 3.8e-21 75.4 3.4 4.8e-21 75.0 2.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETN97529.1 - 1.2e-11 44.1 1.1 1.4e-11 43.9 0.8 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase MSV199 PF10553.4 ETN97529.1 - 0.022 14.6 0.8 4.5 7.1 0.6 2.2 1 1 1 2 2 2 0 MSV199 domain Med6 PF04934.9 ETN97529.1 - 0.058 12.9 0.2 0.13 11.7 0.1 1.6 1 0 0 1 1 1 0 MED6 mediator sub complex component gp32 PF08804.5 ETN97530.1 - 0.007 16.4 0.6 0.012 15.7 0.4 1.4 1 0 0 1 1 1 1 gp32 DNA binding protein like DUF1308 PF07000.6 ETN97531.1 - 0.0028 16.3 2.1 0.0032 16.1 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) Lebercilin PF15619.1 ETN97531.1 - 0.0059 16.0 10.9 0.0059 16.0 7.6 2.0 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease Pyr_excise PF03013.9 ETN97531.1 - 0.0097 15.6 7.4 0.017 14.9 4.9 1.5 1 1 0 1 1 1 1 Pyrimidine dimer DNA glycosylase DUF3584 PF12128.3 ETN97531.1 - 0.03 11.7 15.4 0.037 11.3 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) YfhO PF09586.5 ETN97531.1 - 0.036 12.1 0.1 0.036 12.1 0.1 1.9 1 1 1 2 2 2 0 Bacterial membrane protein YfhO Geminin PF07412.7 ETN97531.1 - 0.041 13.5 16.5 0.28 10.8 5.8 2.2 2 0 0 2 2 2 0 Geminin TMF_TATA_bd PF12325.3 ETN97531.1 - 0.18 11.5 15.6 0.091 12.5 3.7 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF2012 PF09430.5 ETN97531.1 - 0.3 10.9 3.4 0.52 10.1 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2012) DUF641 PF04859.7 ETN97531.1 - 0.36 10.5 16.0 1 9.1 4.9 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF4140 PF13600.1 ETN97531.1 - 0.53 10.7 9.1 2.2 8.7 1.6 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF972 PF06156.8 ETN97531.1 - 1 9.7 23.0 1.2 9.4 8.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) cwf21 PF08312.7 ETN97531.1 - 2.9 7.8 8.0 0.35 10.7 0.8 2.4 2 0 0 2 2 2 0 cwf21 domain Pox_A_type_inc PF04508.7 ETN97531.1 - 3.6 7.6 7.2 27 4.8 0.4 3.7 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat Tnp_P_element PF12017.3 ETN97531.1 - 5.2 6.2 16.9 5.6 6.1 4.9 2.2 1 1 1 2 2 2 0 Transposase protein DUF4200 PF13863.1 ETN97531.1 - 6.5 6.7 28.2 1.5 8.8 2.9 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF1192 PF06698.6 ETN97531.1 - 8.9 6.2 6.5 16 5.3 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) Kelch_4 PF13418.1 ETN97532.1 - 6.8e-07 28.9 0.3 0.00082 19.0 0.0 2.7 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETN97532.1 - 1.1e-06 28.1 0.2 2.8e-05 23.6 0.2 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.20 ETN97532.1 - 5.7e-06 25.7 1.1 1.6e-05 24.3 0.2 2.0 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETN97532.1 - 8.5e-05 22.5 1.2 0.0037 17.3 0.2 2.4 1 1 1 2 2 2 1 Kelch motif Kelch_5 PF13854.1 ETN97532.1 - 0.00011 22.0 1.4 0.00065 19.5 0.6 2.2 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETN97532.1 - 0.0043 17.1 0.0 0.027 14.6 0.0 2.2 2 0 0 2 2 2 1 Galactose oxidase, central domain Smr PF01713.16 ETN97532.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 2 0 0 2 2 2 0 Smr domain YhdB PF14148.1 ETN97533.1 - 0.23 11.2 4.5 0.26 11.0 0.5 2.6 1 1 2 3 3 3 0 YhdB-like protein HEAT_2 PF13646.1 ETN97534.1 - 7.3e-09 35.7 0.0 0.0064 16.7 0.0 5.0 5 1 1 6 6 6 2 HEAT repeats HEAT_EZ PF13513.1 ETN97534.1 - 0.00043 20.6 0.0 0.17 12.4 0.0 4.2 4 0 0 4 4 4 1 HEAT-like repeat HEAT PF02985.17 ETN97534.1 - 0.0053 16.7 0.2 0.71 10.1 0.0 4.5 6 0 0 6 6 6 1 HEAT repeat Gp-FAR-1 PF05823.7 ETN97534.1 - 0.11 12.4 4.9 0.24 11.3 0.1 2.6 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Leu_Phe_trans PF03588.9 ETN97536.1 - 0.049 12.7 0.1 0.059 12.5 0.1 1.1 1 0 0 1 1 1 0 Leucyl/phenylalanyl-tRNA protein transferase Peptidase_S49_N PF08496.5 ETN97537.1 - 0.29 10.9 6.0 0.32 10.7 4.1 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Peptidase_C1 PF00112.18 ETN97540.1 - 1.4e-59 201.6 5.3 2.4e-59 200.8 3.7 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 ETN97540.1 - 4.5e-14 52.4 0.7 8.9e-14 51.5 0.5 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) WD40 PF00400.27 ETN97542.1 - 7e-17 60.5 7.8 7.9e-05 22.3 0.0 4.1 3 1 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN97542.1 - 0.0072 14.5 0.3 0.038 12.1 0.2 1.9 1 1 1 2 2 2 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETN97542.1 - 0.25 11.1 2.8 9.8 5.9 0.1 3.1 1 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Homez PF11569.3 ETN97543.1 - 0.024 13.6 1.1 0.05 12.6 0.7 1.6 1 1 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Homez PF11569.3 ETN97544.1 - 0.038 13.0 0.7 0.088 11.8 0.5 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Chal_sti_synt_N PF00195.14 ETN97544.1 - 0.097 11.9 0.1 0.12 11.6 0.1 1.0 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain HlyD_2 PF12700.2 ETN97544.1 - 1.7 7.7 7.3 2.1 7.4 5.1 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Nop14 PF04147.7 ETN97544.1 - 2.5 5.9 16.0 2.6 5.8 11.1 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 ETN97544.1 - 4.7 5.8 18.1 5.1 5.7 12.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 ETN97544.1 - 4.9 5.5 16.8 5.2 5.4 11.6 1.1 1 0 0 1 1 1 0 Daxx Family AIG1 PF04548.11 ETN97545.1 - 1.1e-08 34.4 0.0 1.7e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 AIG1 family TelA PF05816.6 ETN97545.1 - 0.017 13.8 0.2 0.04 12.6 0.0 1.5 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) FliT PF05400.8 ETN97545.1 - 0.24 11.8 1.5 8.9 6.8 0.6 2.6 2 2 0 2 2 2 0 Flagellar protein FliT AIG1 PF04548.11 ETN97546.1 - 5.6e-12 45.2 0.0 1.1e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 ETN97546.1 - 4e-05 23.5 0.0 8.3e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Hemocyanin_N PF03722.9 ETN97547.1 - 0.035 14.2 0.1 0.044 13.9 0.1 1.2 1 0 0 1 1 1 0 Hemocyanin, all-alpha domain Pkinase PF00069.20 ETN97548.1 - 2.6e-18 66.1 0.0 8.1e-18 64.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETN97548.1 - 0.029 13.4 0.0 0.05 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase DUF2540 PF10802.3 ETN97548.1 - 0.032 13.8 0.1 0.076 12.6 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2540) TPR_12 PF13424.1 ETN97549.1 - 8.5e-16 57.6 5.5 1.8e-09 37.4 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETN97549.1 - 3.3e-09 35.8 2.1 2.7e-06 26.7 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETN97549.1 - 3.3e-09 36.2 5.1 5.6e-08 32.3 0.2 3.2 2 1 1 3 3 3 1 TPR repeat TPR_2 PF07719.12 ETN97549.1 - 2.7e-07 29.9 2.4 1.3e-05 24.7 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETN97549.1 - 3.9e-07 29.4 0.7 2.4e-06 26.9 0.5 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETN97549.1 - 7.9e-07 28.8 0.0 2.3e-05 24.1 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETN97549.1 - 1.8e-05 24.1 0.5 0.00042 19.9 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETN97549.1 - 0.0047 17.2 0.3 0.045 14.2 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Lipase_GDSL_3 PF14606.1 ETN97549.1 - 0.015 15.0 1.9 1.2 8.8 0.3 2.2 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family TPR_16 PF13432.1 ETN97549.1 - 0.16 12.6 0.0 0.52 11.0 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Mob_Pre PF01076.14 ETN97549.1 - 5.9 6.4 8.8 0.33 10.5 0.1 2.7 3 1 0 3 3 3 0 Plasmid recombination enzyme WD40 PF00400.27 ETN97550.1 - 2.6e-54 179.2 4.9 2.7e-11 42.8 0.0 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 ETN97550.1 - 7.3e-10 38.8 0.9 1.5e-06 28.0 0.1 2.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETN97550.1 - 2.7e-09 35.7 3.0 0.034 12.2 0.1 3.2 1 1 2 3 3 3 3 Nucleoporin Nup120/160 PD40 PF07676.7 ETN97550.1 - 4.3e-06 26.2 4.0 0.94 9.2 0.0 4.3 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETN97550.1 - 2e-05 23.5 2.4 0.62 8.7 0.0 3.3 1 1 2 3 3 3 3 Nup133 N terminal like Resistin PF06954.6 ETN97550.1 - 0.0093 16.2 0.3 3.8 7.8 0.1 3.3 1 1 3 4 4 4 1 Resistin RicinB_lectin_2 PF14200.1 ETN97550.1 - 0.018 15.4 0.1 0.19 12.1 0.0 2.6 1 1 2 3 3 3 0 Ricin-type beta-trefoil lectin domain-like Cytochrom_D1 PF02239.11 ETN97550.1 - 0.024 12.9 0.0 0.62 8.2 0.0 2.4 1 1 1 2 2 2 0 Cytochrome D1 heme domain Nup88 PF10168.4 ETN97550.1 - 0.049 11.4 0.0 0.087 10.6 0.0 1.3 2 0 0 2 2 2 0 Nuclear pore component Arylsulfotran_2 PF14269.1 ETN97550.1 - 0.051 12.7 0.3 0.11 11.6 0.2 1.8 1 1 0 1 1 1 0 Arylsulfotransferase (ASST) PLD_C PF12357.3 ETN97550.1 - 0.13 11.7 0.3 35 4.0 0.0 3.7 3 1 1 4 4 4 0 Phospholipase D C terminal Proteasome_A_N PF10584.4 ETN97550.1 - 0.14 11.5 5.8 20 4.6 0.0 3.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature TPR_11 PF13414.1 ETN97551.1 - 4.6e-07 29.3 0.0 1.3e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 TPR repeat TPR_17 PF13431.1 ETN97551.1 - 2.1e-05 24.3 0.0 8.3e-05 22.4 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETN97551.1 - 2.7e-05 23.5 1.4 0.00017 21.0 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETN97551.1 - 0.00034 20.3 3.6 0.00039 20.1 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETN97551.1 - 0.00052 19.8 0.0 0.0019 18.1 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETN97551.1 - 0.0013 19.3 0.0 0.0028 18.3 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETN97551.1 - 0.0024 17.5 0.2 0.0024 17.5 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETN97551.1 - 0.0032 17.7 0.0 0.01 16.1 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat Sin3_corepress PF08295.7 ETN97551.1 - 0.07 12.8 4.1 1.7 8.4 0.3 2.8 1 1 1 2 2 2 0 Sin3 family co-repressor CAP_GLY PF01302.20 ETN97552.1 - 0.1 12.3 0.4 1.9 8.2 0.1 2.6 2 1 0 2 2 2 0 CAP-Gly domain DUF2265 PF10023.4 ETN97553.1 - 0.042 12.9 2.6 0.047 12.8 1.8 1.2 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) DUF4263 PF14082.1 ETN97553.1 - 0.068 13.1 1.4 0.092 12.6 0.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4263) NPR3 PF03666.8 ETN97553.1 - 0.078 11.5 4.8 0.092 11.2 3.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM60A PF15396.1 ETN97553.1 - 0.25 11.0 5.0 0.29 10.8 3.5 1.0 1 0 0 1 1 1 0 Protein Family FAM60A USP8_interact PF08941.5 ETN97553.1 - 0.54 9.5 2.9 0.57 9.4 0.5 1.8 2 0 0 2 2 2 0 USP8 interacting Mgr1 PF08602.5 ETN97553.1 - 0.86 8.5 5.2 1 8.3 3.6 1.0 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit DUF2968 PF11180.3 ETN97553.1 - 1.2 8.5 5.7 1.7 7.9 4.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) Prefoldin_2 PF01920.15 ETN97553.1 - 2.2 8.0 12.4 0.11 12.2 3.0 2.0 1 1 1 2 2 2 0 Prefoldin subunit RasGEF_N_2 PF14663.1 ETN97554.1 - 0.0061 16.4 0.3 0.008 16.1 0.2 1.1 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain WD40 PF00400.27 ETN97555.1 - 3.3e-21 74.3 5.4 2.1e-11 43.2 0.5 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN97555.1 - 1.2e-06 27.0 0.1 1.5e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 NTNH_C PF08470.5 ETN97555.1 - 0.033 13.8 1.2 0.41 10.2 0.9 2.4 1 1 1 2 2 2 0 Nontoxic nonhaemagglutinin C-terminal RRN7 PF11781.3 ETN97555.1 - 0.078 12.4 0.4 0.82 9.2 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 BIR PF00653.16 ETN97555.1 - 0.85 10.0 3.3 0.6 10.5 0.3 2.0 1 1 1 2 2 2 0 Inhibitor of Apoptosis domain Kelch_6 PF13964.1 ETN97556.1 - 0.014 15.5 1.1 0.036 14.2 0.0 2.2 2 1 0 2 2 2 0 Kelch motif MutS_I PF01624.15 ETN97557.1 - 5.7e-30 103.6 0.1 9.4e-30 102.9 0.1 1.4 1 0 0 1 1 1 1 MutS domain I Daxx PF03344.10 ETN97557.1 - 2.5 6.4 26.8 3.5 5.9 18.6 1.2 1 0 0 1 1 1 0 Daxx Family MIP-T3 PF10243.4 ETN97557.1 - 3.4 6.0 35.0 4.5 5.6 24.3 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RSN1_TM PF13967.1 ETN97558.1 - 0.083 12.4 0.4 0.21 11.1 0.3 1.7 1 1 0 1 1 1 0 Late exocytosis, associated with Golgi transport Yippee-Mis18 PF03226.9 ETN97560.1 - 3.1e-10 39.9 2.6 3.1e-10 39.9 1.8 2.0 2 1 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly APG6 PF04111.7 ETN97560.1 - 0.00085 18.4 16.6 0.0012 17.9 11.5 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 V_ATPase_I PF01496.14 ETN97560.1 - 0.002 16.0 5.9 0.0023 15.9 4.1 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family GFA PF04828.9 ETN97560.1 - 0.0044 16.9 6.3 0.022 14.7 0.4 2.9 2 1 1 3 3 3 1 Glutathione-dependent formaldehyde-activating enzyme bZIP_1 PF00170.16 ETN97560.1 - 0.005 16.7 23.3 0.0058 16.5 4.4 3.0 1 1 0 2 2 2 1 bZIP transcription factor Reo_sigmaC PF04582.7 ETN97560.1 - 0.007 15.5 3.9 0.012 14.8 2.4 1.5 1 1 1 2 2 2 1 Reovirus sigma C capsid protein Prominin PF05478.6 ETN97560.1 - 0.011 13.3 8.5 0.015 12.9 5.9 1.1 1 0 0 1 1 1 0 Prominin IncA PF04156.9 ETN97560.1 - 0.018 14.6 22.4 0.13 11.8 15.5 2.0 1 1 0 1 1 1 0 IncA protein DUF3584 PF12128.3 ETN97560.1 - 0.023 12.0 12.4 0.028 11.7 8.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Exonuc_VII_L PF02601.10 ETN97560.1 - 0.033 13.3 4.9 0.034 13.3 3.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cluap1 PF10234.4 ETN97560.1 - 0.034 13.3 15.0 0.049 12.8 10.4 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF812 PF05667.6 ETN97560.1 - 0.037 12.5 14.9 0.053 12.0 10.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ERM PF00769.14 ETN97560.1 - 0.052 13.0 21.4 0.085 12.3 14.8 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Flagellin_N PF00669.15 ETN97560.1 - 0.061 13.1 5.1 0.081 12.7 2.6 1.8 1 1 0 1 1 1 0 Bacterial flagellin N-terminal helical region CALCOCO1 PF07888.6 ETN97560.1 - 0.084 11.1 10.9 0.1 10.8 7.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like CCDC155 PF14662.1 ETN97560.1 - 0.1 12.2 20.5 0.19 11.2 14.2 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DUF773 PF05600.7 ETN97560.1 - 0.1 11.3 8.9 0.13 10.9 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF773) DUF2400 PF09674.5 ETN97560.1 - 0.11 12.2 4.1 0.16 11.6 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) zf-HYPF PF07503.7 ETN97560.1 - 0.13 11.6 1.8 7.4 6.0 0.6 2.8 2 0 0 2 2 2 0 HypF finger EzrA PF06160.7 ETN97560.1 - 0.13 10.3 12.3 0.18 9.9 8.5 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA AAA_27 PF13514.1 ETN97560.1 - 0.14 9.8 10.7 0.17 9.4 7.4 1.1 1 0 0 1 1 1 0 AAA domain Syntaxin_2 PF14523.1 ETN97560.1 - 0.18 11.8 13.5 4.5 7.3 9.4 2.4 1 1 0 1 1 1 0 Syntaxin-like protein LMBR1 PF04791.11 ETN97560.1 - 0.19 10.3 2.4 0.2 10.2 1.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein LXG PF04740.7 ETN97560.1 - 0.19 11.5 10.4 0.95 9.2 7.4 1.8 1 1 0 1 1 1 0 LXG domain of WXG superfamily PEARLI-4 PF05278.7 ETN97560.1 - 0.19 11.0 15.7 0.099 11.9 9.4 1.5 1 1 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) zf-C4H2 PF10146.4 ETN97560.1 - 0.31 11.0 16.2 0.52 10.2 11.2 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein Sec5 PF15469.1 ETN97560.1 - 0.41 10.3 9.8 0.61 9.7 6.8 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec5 GAS PF13851.1 ETN97560.1 - 0.55 9.3 23.9 0.064 12.4 12.2 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1395 PF07160.7 ETN97560.1 - 0.65 9.4 14.5 0.99 8.8 10.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) DUF1664 PF07889.7 ETN97560.1 - 0.86 9.4 10.4 0.36 10.6 3.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF972 PF06156.8 ETN97560.1 - 0.86 9.9 19.9 34 4.8 13.7 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF972) AAA_11 PF13086.1 ETN97560.1 - 1 8.8 7.7 1.5 8.3 5.4 1.3 1 0 0 1 1 1 0 AAA domain DUF3571 PF12095.3 ETN97560.1 - 1.2 9.3 9.0 3.4 7.9 3.9 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3571) DUF342 PF03961.8 ETN97560.1 - 1.4 7.2 17.6 2.9 6.2 12.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) CorA PF01544.13 ETN97560.1 - 1.4 7.8 7.0 5.5 5.9 5.1 1.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2205 PF10224.4 ETN97560.1 - 1.4 8.5 16.1 7.2 6.2 1.0 3.1 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) CtIP_N PF10482.4 ETN97560.1 - 1.4 8.7 19.3 0.24 11.2 8.7 2.5 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Spc7 PF08317.6 ETN97560.1 - 1.5 7.3 19.8 0.11 11.1 5.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Tox-ODYAM1 PF15642.1 ETN97560.1 - 1.6 7.2 8.6 2.2 6.8 6.0 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus DivIC PF04977.10 ETN97560.1 - 2 7.9 21.0 11 5.5 4.0 3.1 1 1 2 3 3 3 0 Septum formation initiator TMPIT PF07851.8 ETN97560.1 - 2.4 7.1 15.3 3.5 6.6 10.3 1.4 1 1 0 1 1 1 0 TMPIT-like protein Mnd1 PF03962.10 ETN97560.1 - 2.4 7.7 22.5 4.2 6.9 12.8 2.0 1 1 0 1 1 1 0 Mnd1 family DUF2968 PF11180.3 ETN97560.1 - 2.4 7.4 13.1 6.7 6.0 9.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) Nup54 PF13874.1 ETN97560.1 - 2.5 7.7 16.6 18 4.9 11.5 2.0 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 ATG16 PF08614.6 ETN97560.1 - 2.8 7.7 20.3 5.2 6.8 13.9 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF3391 PF11871.3 ETN97560.1 - 2.9 8.0 9.1 0.36 11.0 2.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) DUF2730 PF10805.3 ETN97560.1 - 3.2 7.5 11.5 4.8 6.9 7.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) Prefoldin_2 PF01920.15 ETN97560.1 - 3.3 7.5 24.6 0.76 9.5 4.9 3.2 1 1 2 3 3 3 0 Prefoldin subunit C1_4 PF07975.7 ETN97560.1 - 4 7.5 6.9 0.99 9.4 0.6 2.8 3 0 0 3 3 2 0 TFIIH C1-like domain DUF2481 PF10654.4 ETN97560.1 - 4.1 7.1 13.9 3.5 7.3 1.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2481) TMF_DNA_bd PF12329.3 ETN97560.1 - 4.2 7.2 28.3 15 5.4 11.5 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding bZIP_Maf PF03131.12 ETN97560.1 - 4.6 7.5 16.7 0.93 9.8 5.3 2.6 1 1 1 2 2 2 0 bZIP Maf transcription factor Seryl_tRNA_N PF02403.17 ETN97560.1 - 4.7 7.2 22.0 7.3 6.6 11.1 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Sas10_Utp3 PF04000.10 ETN97560.1 - 5 7.3 15.5 29 4.9 1.5 3.7 2 1 1 3 3 3 0 Sas10/Utp3/C1D family DUF904 PF06005.7 ETN97560.1 - 5.1 7.4 27.2 1.2 9.4 3.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF904) ADIP PF11559.3 ETN97560.1 - 5.4 6.9 22.2 8.8 6.2 10.8 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Kinesin-relat_1 PF12711.2 ETN97560.1 - 5.8 7.3 20.3 1.2 9.5 4.2 3.1 1 1 2 3 3 3 0 Kinesin motor DUF4407 PF14362.1 ETN97560.1 - 6.4 5.6 12.2 14 4.5 8.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3450 PF11932.3 ETN97560.1 - 7.4 5.7 13.5 45 3.1 8.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Med4 PF10018.4 ETN97560.1 - 8 5.8 20.2 0.89 8.9 6.3 2.1 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF948 PF06103.6 ETN97560.1 - 9.8 6.1 8.3 55 3.7 5.5 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) UCH PF00443.24 ETN97561.1 - 1.6e-13 50.3 15.6 3.5e-13 49.2 10.8 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETN97561.1 - 0.00036 20.0 15.2 0.014 14.8 8.6 3.1 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF1987 PF09345.5 ETN97561.1 - 0.14 11.9 4.9 0.087 12.6 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1987) DUF4200 PF13863.1 ETN97562.1 - 0.0015 18.4 6.6 0.0024 17.8 4.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) DUF554 PF04474.7 ETN97562.1 - 0.096 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF554) YqfQ PF14181.1 ETN97562.1 - 0.27 11.2 3.4 0.38 10.7 2.4 1.2 1 0 0 1 1 1 0 YqfQ-like protein NAD_binding_5 PF07994.7 ETN97562.1 - 1.9 7.8 6.4 8.7 5.7 4.1 1.9 1 1 0 2 2 2 0 Myo-inositol-1-phosphate synthase Daxx PF03344.10 ETN97563.1 - 0.31 9.4 18.2 0.41 9.0 12.6 1.0 1 0 0 1 1 1 0 Daxx Family DUF912 PF06024.7 ETN97563.1 - 0.41 10.7 17.5 0.032 14.2 4.8 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) RRN3 PF05327.6 ETN97563.1 - 9 4.2 12.7 18 3.2 8.8 1.5 1 1 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 C2 PF00168.25 ETN97565.1 - 0.016 15.0 0.1 0.054 13.3 0.1 1.9 2 0 0 2 2 2 0 C2 domain CS PF04969.11 ETN97566.1 - 9.3e-10 38.9 0.1 2.1e-09 37.8 0.1 1.6 1 0 0 1 1 1 1 CS domain HSP20 PF00011.16 ETN97566.1 - 0.0056 16.5 1.5 0.018 14.9 0.0 2.3 2 0 0 2 2 2 1 Hsp20/alpha crystallin family Atrophin-1 PF03154.10 ETN97566.1 - 7.9 4.4 8.0 11 3.9 5.5 1.2 1 0 0 1 1 1 0 Atrophin-1 family CS PF04969.11 ETN97567.1 - 3.1e-10 40.4 0.1 8.5e-10 39.0 0.1 1.7 1 0 0 1 1 1 1 CS domain HSP20 PF00011.16 ETN97567.1 - 0.014 15.2 0.0 0.014 15.2 0.0 2.1 2 1 0 2 2 2 0 Hsp20/alpha crystallin family DUF3155 PF11352.3 ETN97568.1 - 0.076 13.2 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3155) WD40 PF00400.27 ETN97569.1 - 5.6e-58 190.8 22.2 5.7e-10 38.6 0.3 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETN97569.1 - 2.5e-08 32.5 10.4 0.0036 15.5 0.1 4.7 1 1 2 4 4 4 4 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETN97569.1 - 7.4e-05 23.0 9.0 0.00022 21.5 5.0 2.7 2 0 0 2 2 2 1 TRAF-type zinc finger Lge1 PF11488.3 ETN97569.1 - 0.37 11.0 6.6 0.95 9.7 4.1 2.1 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 DUF641 PF04859.7 ETN97569.1 - 5.8 6.6 12.7 2.4 7.9 6.6 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) RGS PF00615.14 ETN97570.1 - 0.02 14.9 1.8 0.25 11.4 0.0 2.3 1 1 0 2 2 2 0 Regulator of G protein signaling domain DUF1938 PF09153.5 ETN97572.1 - 0.56 10.0 5.0 0.33 10.8 1.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1938) Adeno_IVa2 PF02456.10 ETN97573.1 - 0.025 13.2 1.9 0.034 12.7 0.3 1.8 1 1 1 2 2 2 0 Adenovirus IVa2 protein Skp1_POZ PF03931.10 ETN97573.1 - 0.031 14.3 0.1 0.084 12.9 0.1 1.6 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain DUF258 PF03193.11 ETN97576.1 - 0.018 14.1 0.1 0.11 11.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 ETN97576.1 - 0.061 13.6 1.6 0.16 12.2 0.0 2.5 3 0 0 3 3 3 0 ABC transporter AAA_16 PF13191.1 ETN97576.1 - 0.11 12.5 0.0 5.4 6.9 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.1 ETN97576.1 - 0.55 10.3 4.7 1.8 8.6 0.1 3.6 3 1 2 5 5 5 0 AAA domain SPX PF03105.14 ETN97577.1 - 0.051 13.3 3.6 0.11 12.2 2.5 1.4 1 0 0 1 1 1 0 SPX domain AAA_5 PF07728.9 ETN97577.1 - 0.08 12.6 0.0 0.67 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF2570 PF10828.3 ETN97578.1 - 0.031 13.8 1.5 0.085 12.4 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) SOBP PF15279.1 ETN97579.1 - 0.66 10.3 5.7 1 9.6 4.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Pkinase_Tyr PF07714.12 ETN97580.1 - 6.8e-53 179.3 0.1 6.1e-26 91.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 ETN97580.1 - 3.9e-45 154.0 0.2 7.2e-22 77.7 0.3 2.1 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.9 ETN97580.1 - 0.22 10.5 1.9 1.4 7.9 1.3 2.0 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kelch_6 PF13964.1 ETN97581.1 - 0.042 14.0 4.8 12 6.3 0.5 4.6 2 2 2 4 4 4 0 Kelch motif SMI1_KNR4 PF09346.5 ETN97581.1 - 0.075 13.0 3.2 0.068 13.1 0.6 2.1 1 1 0 2 2 2 0 SMI1 / KNR4 family (SUKH-1) DeoC PF01791.4 ETN97582.1 - 2.8e-40 138.0 2.8 1.7e-19 70.0 1.0 2.5 2 1 0 2 2 2 2 DeoC/LacD family aldolase MH1 PF03165.11 ETN97582.1 - 0.047 13.6 1.0 0.14 12.1 0.0 2.3 2 1 1 3 3 3 0 MH1 domain PcrB PF01884.12 ETN97582.1 - 0.11 11.7 4.4 0.1 11.7 0.3 2.1 2 0 0 2 2 2 0 PcrB family Peptidase_S3 PF00944.14 ETN97583.1 - 0.0096 15.3 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 1 Alphavirus core protein Sec62 PF03839.11 ETN97584.1 - 1.6 8.1 15.4 0.6 9.4 9.0 1.5 1 1 1 2 2 2 0 Translocation protein Sec62 PRP21_like_P PF12230.3 ETN97587.1 - 6.3e-18 65.1 0.6 6.3e-18 65.1 0.4 2.8 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein TraC PF07820.7 ETN97587.1 - 0.16 12.1 6.7 0.55 10.4 3.2 2.6 2 0 0 2 2 2 0 TraC-like protein Cut12 PF11500.3 ETN97587.1 - 1 9.0 15.2 0.08 12.6 0.7 3.8 3 1 0 3 3 3 0 Spindle pole body formation-associated protein Filament PF00038.16 ETN97590.1 - 0.0021 17.5 4.9 0.13 11.7 0.6 2.0 2 0 0 2 2 2 2 Intermediate filament protein WEMBL PF05701.6 ETN97590.1 - 0.0066 14.9 13.0 0.19 10.1 0.6 2.0 2 0 0 2 2 2 2 Weak chloroplast movement under blue light CENP-F_leu_zip PF10473.4 ETN97590.1 - 0.0068 16.2 17.6 0.054 13.3 4.8 2.1 2 0 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 ETN97590.1 - 0.043 13.5 16.2 0.49 10.1 4.0 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein FliJ PF02050.11 ETN97590.1 - 0.065 13.2 8.0 0.26 11.3 5.6 1.8 1 1 0 1 1 1 0 Flagellar FliJ protein Prefoldin_2 PF01920.15 ETN97590.1 - 0.067 12.9 11.8 0.12 12.1 2.2 2.2 2 0 0 2 2 2 0 Prefoldin subunit Cast PF10174.4 ETN97590.1 - 0.091 10.8 12.4 0.096 10.7 2.4 1.9 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone V-SNARE PF05008.10 ETN97590.1 - 0.12 12.5 4.0 2.6 8.2 0.3 2.4 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus MscS_porin PF12795.2 ETN97590.1 - 0.12 11.6 9.4 0.044 13.1 1.3 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF2524 PF10732.4 ETN97590.1 - 0.12 12.4 3.7 4.3 7.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) Golgin_A5 PF09787.4 ETN97590.1 - 0.12 10.8 11.4 0.1 11.0 1.5 2.0 1 1 1 2 2 2 0 Golgin subfamily A member 5 Phage_GP20 PF06810.6 ETN97590.1 - 0.14 11.5 7.7 1.6 8.1 0.7 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 DUF2408 PF10303.4 ETN97590.1 - 0.19 11.8 5.5 0.43 10.6 3.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) G-gamma PF00631.17 ETN97590.1 - 0.21 11.3 6.8 0.95 9.2 0.9 2.4 2 1 0 2 2 2 0 GGL domain HrpB7 PF09486.5 ETN97590.1 - 0.21 11.4 4.0 0.29 11.0 0.3 2.0 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) MAD PF05557.8 ETN97590.1 - 0.29 9.1 12.5 0.43 8.5 1.9 2.0 2 0 0 2 2 2 0 Mitotic checkpoint protein DUF1043 PF06295.7 ETN97590.1 - 0.45 10.1 9.8 1.5 8.4 1.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1043) Sec8_exocyst PF04048.9 ETN97590.1 - 0.47 10.0 6.2 0.85 9.2 0.5 2.1 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Spc7 PF08317.6 ETN97590.1 - 0.5 8.9 11.8 0.93 8.0 2.6 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF745 PF05335.8 ETN97590.1 - 0.51 9.8 5.9 2.4 7.6 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF745) GrpE PF01025.14 ETN97590.1 - 0.75 9.3 10.8 1.8 8.0 3.3 2.0 2 0 0 2 2 2 0 GrpE DegS PF05384.6 ETN97590.1 - 0.77 8.9 9.0 4 6.6 2.0 2.1 2 0 0 2 2 2 0 Sensor protein DegS Cortex-I_coil PF09304.5 ETN97590.1 - 0.83 9.7 11.1 3.3 7.7 0.4 2.1 2 0 0 2 2 2 0 Cortexillin I, coiled coil Erp_C PF06780.6 ETN97590.1 - 0.94 9.3 6.6 7 6.4 0.1 2.1 2 0 0 2 2 2 0 Erp protein C-terminus TBPIP PF07106.8 ETN97590.1 - 1.2 8.7 8.4 3.8 7.0 1.1 2.0 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fez1 PF06818.10 ETN97590.1 - 1.2 9.0 9.8 0.77 9.7 2.5 2.0 2 0 0 2 2 2 0 Fez1 Bacillus_HBL PF05791.6 ETN97590.1 - 1.2 8.4 7.6 3.6 6.9 4.4 1.9 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Prefoldin_3 PF13758.1 ETN97590.1 - 1.3 8.8 5.7 1.3 8.8 0.8 2.0 2 0 0 2 2 2 0 Prefoldin subunit Ax_dynein_light PF10211.4 ETN97590.1 - 1.4 8.7 9.7 0.53 10.0 1.3 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain HAUS5 PF14817.1 ETN97590.1 - 1.4 7.3 9.9 6.2 5.2 6.9 1.8 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 5 Laminin_II PF06009.7 ETN97590.1 - 1.8 8.2 6.4 1.1 8.9 0.9 2.0 2 0 0 2 2 2 0 Laminin Domain II DUF4140 PF13600.1 ETN97590.1 - 1.9 9.0 7.5 8.4 6.8 1.6 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) HR1 PF02185.11 ETN97590.1 - 2.1 8.1 8.4 0.69 9.6 0.7 2.4 2 1 0 2 2 2 0 Hr1 repeat DUF4618 PF15397.1 ETN97590.1 - 2.1 7.6 11.0 3.8 6.7 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Seryl_tRNA_N PF02403.17 ETN97590.1 - 2.2 8.3 11.7 3.7 7.6 1.9 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3763 PF12592.3 ETN97590.1 - 2.4 7.8 7.0 2.9 7.6 0.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3763) GAS PF13851.1 ETN97590.1 - 2.4 7.3 12.9 7.7 5.6 8.9 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 ETN97590.1 - 3.2 7.2 10.4 5.5 6.5 1.5 2.0 2 0 0 2 2 2 0 IncA protein bZIP_Maf PF03131.12 ETN97590.1 - 3.4 8.0 10.1 8.7 6.7 1.0 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor WXG100 PF06013.7 ETN97590.1 - 3.5 7.7 5.9 11 6.0 0.5 2.2 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Rootletin PF15035.1 ETN97590.1 - 3.9 7.4 13.1 0.83 9.6 0.9 2.1 1 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion H-kinase_dim PF02895.9 ETN97590.1 - 4 7.8 5.5 23 5.4 0.4 2.2 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain OEP PF02321.13 ETN97590.1 - 4.4 6.8 6.9 5.4 6.5 2.2 2.0 2 0 0 2 2 2 0 Outer membrane efflux protein EMP24_GP25L PF01105.19 ETN97590.1 - 5 6.8 6.4 4.6 6.9 2.2 1.8 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Bap31 PF05529.7 ETN97590.1 - 5.2 6.4 11.3 1.8e+02 1.4 7.8 2.0 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like Spc24 PF08286.6 ETN97590.1 - 6.6 6.4 11.7 5.3 6.7 2.1 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF4201 PF13870.1 ETN97590.1 - 7.2 6.0 13.7 1.8 7.9 3.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF972 PF06156.8 ETN97590.1 - 7.9 6.8 10.2 10 6.5 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF904 PF06005.7 ETN97590.1 - 8.2 6.8 13.0 8.5 6.7 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF2422 PF10337.4 ETN97590.1 - 8.3 5.0 7.5 12 4.4 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) Sugarporin_N PF11471.3 ETN97590.1 - 9.2 5.9 20.8 2.5 7.8 4.8 3.6 2 2 1 3 3 3 0 Maltoporin periplasmic N-terminal extension DUF4200 PF13863.1 ETN97590.1 - 9.4 6.2 15.1 6 6.8 3.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) YlqD PF11068.3 ETN97590.1 - 9.7 6.2 12.5 4.6 7.2 1.0 2.0 1 1 0 2 2 2 0 YlqD protein CPSF73-100_C PF11718.3 ETN97591.1 - 3.2 7.0 11.5 1.4 8.2 6.6 1.4 1 1 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Tom37_C PF11801.3 ETN97593.1 - 0.09 12.6 2.0 0.76 9.6 1.3 2.0 2 0 0 2 2 2 0 Tom37 C-terminal domain RNA_pol_Rpb1_1 PF04997.7 ETN97594.1 - 0.065 12.4 9.3 0.072 12.3 6.5 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 DUF3366 PF11846.3 ETN97594.1 - 0.13 12.1 2.3 0.17 11.7 1.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) DUF2971 PF11185.3 ETN97594.1 - 0.14 12.8 2.9 0.19 12.4 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2971) Menin PF05053.8 ETN97594.1 - 0.17 10.0 3.4 0.18 9.9 2.4 1.0 1 0 0 1 1 1 0 Menin Membralin PF09746.4 ETN97594.1 - 1.6 7.6 3.8 1.9 7.4 2.6 1.0 1 0 0 1 1 1 0 Tumour-associated protein Nop25 PF09805.4 ETN97595.1 - 0.12 12.4 18.9 0.13 12.3 13.1 1.0 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) NST1 PF13945.1 ETN97595.1 - 0.23 11.5 10.3 0.28 11.2 7.2 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator FKBP_N PF01346.13 ETN97596.1 - 1.1 9.3 5.8 1.2 9.1 4.1 1.2 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase FmdE PF02663.9 ETN97596.1 - 3.6 7.5 6.9 4.1 7.3 4.8 1.1 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon WD40 PF00400.27 ETN97597.1 - 2.5e-21 74.7 8.3 3e-08 33.2 0.0 5.0 4 2 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN97597.1 - 2.7e-07 29.0 0.1 0.012 13.8 0.0 3.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETN97597.1 - 0.07 12.9 1.2 7.8 6.3 0.2 3.1 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Phage_holin_4 PF05105.7 ETN97599.1 - 0.027 14.1 0.1 0.88 9.2 0.0 2.1 1 1 1 2 2 2 0 Holin family BAH PF01426.13 ETN97600.1 - 0.17 11.6 1.2 1.6 8.5 0.2 2.5 2 1 1 3 3 3 0 BAH domain Peptidase_M1 PF01433.15 ETN97602.1 - 1.1e-05 24.6 0.0 1.4e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 DUF3369 PF11849.3 ETN97603.1 - 0.009 15.9 0.1 0.013 15.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3369) DUF3513 PF12026.3 ETN97603.1 - 0.017 14.7 3.7 0.023 14.2 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) PBP_sp32 PF07222.7 ETN97603.1 - 1.4 8.0 6.7 2.1 7.4 4.6 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Peptidase_S49_N PF08496.5 ETN97603.1 - 3.7 7.3 12.8 6.7 6.4 8.9 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal WD40 PF00400.27 ETN97604.1 - 6.2e-23 79.7 5.5 6.2e-11 41.7 0.4 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETN97604.1 - 4.6e-05 21.7 5.6 0.00016 19.9 1.0 2.4 2 1 0 3 3 3 1 Nucleoporin Nup120/160 Gp58 PF07902.6 ETN97604.1 - 0.00019 19.8 7.7 0.00026 19.3 5.3 1.2 1 0 0 1 1 1 1 gp58-like protein Atg14 PF10186.4 ETN97604.1 - 0.013 14.4 11.1 0.015 14.2 7.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Syntaphilin PF15290.1 ETN97604.1 - 0.061 12.7 9.2 0.076 12.4 6.4 1.1 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Lipoprotein_3 PF00938.12 ETN97604.1 - 0.14 11.9 11.9 0.075 12.8 2.5 2.9 1 1 2 3 3 3 0 Lipoprotein UB2H PF14814.1 ETN97604.1 - 0.8 9.4 5.5 0.2 11.4 0.9 2.2 2 1 1 3 3 3 0 Bifunctional transglycosylase second domain Ly49 PF08391.5 ETN97604.1 - 2.3 8.3 19.2 0.24 11.5 4.0 2.6 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region NOP5NT PF08156.8 ETN97604.1 - 6.5 6.9 7.2 2.5 8.3 0.5 3.4 2 1 1 3 3 3 0 NOP5NT (NUC127) domain TPR_MLP1_2 PF07926.7 ETN97607.1 - 0.0059 16.3 8.7 0.0059 16.3 6.0 6.9 2 2 3 6 6 6 3 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 ETN97607.1 - 0.037 13.8 67.9 0.18 11.6 5.8 5.1 2 2 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 ETN97607.1 - 0.047 12.8 71.3 0.36 9.9 13.2 5.2 2 2 1 4 4 4 0 Growth-arrest specific micro-tubule binding Syntaxin-6_N PF09177.6 ETN97607.1 - 0.1 13.0 47.2 1.9 8.9 1.3 5.5 3 3 2 5 5 5 0 Syntaxin 6, N-terminal Reo_sigmaC PF04582.7 ETN97607.1 - 0.2 10.7 26.4 0.75 8.9 1.6 4.1 2 2 1 4 4 4 0 Reovirus sigma C capsid protein IncA PF04156.9 ETN97607.1 - 0.22 11.1 74.2 0.68 9.4 18.3 4.4 1 1 1 2 2 2 0 IncA protein ATG16 PF08614.6 ETN97607.1 - 1.5 8.5 73.6 0.33 10.7 5.6 5.0 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) CCDC155 PF14662.1 ETN97607.1 - 1.9 8.0 70.4 0.035 13.7 3.4 4.9 2 2 2 4 4 4 0 Coiled-coil region of CCDC155 ADIP PF11559.3 ETN97607.1 - 2.8 7.8 72.2 2.5 8.0 7.2 4.8 1 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Phage_CII PF05269.6 ETN97610.1 - 0.092 12.7 0.1 1.3 9.0 0.0 2.7 3 0 0 3 3 3 0 Bacteriophage CII protein PPR_2 PF13041.1 ETN97613.1 - 6.3e-14 51.6 1.8 2.6e-08 33.6 0.1 3.1 2 1 1 3 3 3 3 PPR repeat family PPR PF01535.15 ETN97613.1 - 1.5e-13 49.7 1.8 8.9e-05 22.2 0.1 3.3 3 0 0 3 3 3 3 PPR repeat PPR_3 PF13812.1 ETN97613.1 - 4.7e-11 42.0 0.0 1.3e-05 25.0 0.0 3.3 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 ETN97613.1 - 1.4e-07 30.8 0.0 0.0018 17.7 0.0 3.1 3 0 0 3 3 3 3 PPR repeat ATP13 PF12921.2 ETN97613.1 - 0.047 13.0 0.7 1.2 8.5 0.0 2.2 1 1 1 2 2 2 0 Mitochondrial ATPase expression WD40 PF00400.27 ETN97614.1 - 6.2e-39 130.5 16.4 6.3e-11 41.7 0.0 6.5 6 1 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETN97614.1 - 2.9e-07 29.0 1.5 0.0091 14.1 0.1 3.9 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Ig_2 PF13895.1 ETN97614.1 - 0.024 14.7 0.3 4.9 7.3 0.1 2.5 2 0 0 2 2 2 0 Immunoglobulin domain DUF1900 PF08954.6 ETN97614.1 - 0.059 12.8 0.0 3.5 7.1 0.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1900) Cupin_8 PF13621.1 ETN97614.1 - 0.12 11.8 5.0 0.21 11.0 3.4 1.5 1 1 0 1 1 1 0 Cupin-like domain DUF883 PF05957.8 ETN97614.1 - 0.59 10.5 5.0 0.32 11.4 1.6 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) OmpH PF03938.9 ETN97614.1 - 1.7 8.5 18.7 2.4 8.0 12.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TMPIT PF07851.8 ETN97614.1 - 9.7 5.1 9.5 15 4.5 6.6 1.3 1 0 0 1 1 1 0 TMPIT-like protein IncA PF04156.9 ETN97615.1 - 0.3 10.6 50.1 0.1 12.2 10.9 2.6 2 1 1 3 3 3 0 IncA protein Pox_A_type_inc PF04508.7 ETN97615.1 - 3.9 7.4 18.0 5.9 6.9 0.2 5.7 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DUF2665 PF11654.3 ETN97617.1 - 0.14 11.7 1.2 0.29 10.7 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2665) NACHT PF05729.7 ETN97618.1 - 0.094 12.3 0.0 0.095 12.3 0.0 1.1 1 0 0 1 1 1 0 NACHT domain WD40 PF00400.27 ETN97619.1 - 3.8e-18 64.5 1.3 8.8e-09 34.9 0.0 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETN97619.1 - 0.022 12.9 0.0 2.2 6.2 0.0 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Attacin_C PF03769.10 ETN97619.1 - 0.078 13.1 0.1 0.14 12.3 0.0 1.3 1 1 0 1 1 1 0 Attacin, C-terminal region Kelch_6 PF13964.1 ETN97619.1 - 0.42 10.8 1.8 5.1 7.4 0.1 2.6 2 0 0 2 2 2 0 Kelch motif BSP_II PF05432.6 ETN97620.1 - 0.00038 19.8 8.2 0.00043 19.6 5.7 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) DUF4471 PF14740.1 ETN97620.1 - 0.015 14.4 7.0 0.015 14.5 4.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4471) VID27 PF08553.5 ETN97620.1 - 0.019 13.2 10.3 0.022 13.0 7.2 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Nucleoplasmin PF03066.10 ETN97620.1 - 0.02 14.4 12.6 0.025 14.1 8.7 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF2457 PF10446.4 ETN97620.1 - 0.02 13.6 12.6 0.022 13.5 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.5 ETN97620.1 - 0.023 14.9 10.5 0.038 14.2 7.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4446 PF14584.1 ETN97620.1 - 0.023 14.4 1.5 0.023 14.4 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) CDC45 PF02724.9 ETN97620.1 - 0.034 12.2 8.6 0.032 12.2 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 ETN97620.1 - 0.039 13.2 7.0 0.046 12.9 4.9 1.2 1 0 0 1 1 1 0 NOA36 protein Bd3614-deam PF14439.1 ETN97620.1 - 0.066 13.0 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase Myc_N PF01056.13 ETN97620.1 - 0.07 12.2 8.0 0.085 12.0 5.6 1.1 1 0 0 1 1 1 0 Myc amino-terminal region DUF3292 PF11696.3 ETN97620.1 - 0.074 10.9 1.1 0.079 10.8 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) TRAP_alpha PF03896.11 ETN97620.1 - 0.093 11.7 7.0 0.1 11.5 4.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Daxx PF03344.10 ETN97620.1 - 0.15 10.5 11.7 0.14 10.6 8.1 1.1 1 0 0 1 1 1 0 Daxx Family Na_trans_assoc PF06512.8 ETN97620.1 - 0.24 11.3 14.2 0.25 11.3 9.8 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated PI3K_1B_p101 PF10486.4 ETN97620.1 - 0.61 7.5 5.0 0.67 7.4 3.5 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit FAM176 PF14851.1 ETN97620.1 - 0.71 9.5 6.3 1.2 8.8 4.4 1.4 1 0 0 1 1 1 0 FAM176 family DDHD PF02862.12 ETN97620.1 - 0.9 9.2 8.1 1.1 9.0 5.6 1.2 1 0 0 1 1 1 0 DDHD domain Retinal PF15449.1 ETN97620.1 - 1 6.9 5.2 1.1 6.8 3.6 1.1 1 0 0 1 1 1 0 Retinal protein CobT PF06213.7 ETN97620.1 - 1.1 8.3 16.0 1.2 8.1 11.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PBP1_TM PF14812.1 ETN97620.1 - 1.1 9.5 11.7 2.3 8.5 8.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RP-C_C PF11800.3 ETN97620.1 - 3.1 7.4 5.9 3.7 7.1 4.1 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Peroxin-13_N PF04088.8 ETN97620.1 - 4.2 7.3 7.2 54 3.7 5.0 2.1 1 1 0 1 1 1 0 Peroxin 13, N-terminal region SURF2 PF05477.6 ETN97620.1 - 5.5 6.0 15.0 7.9 5.5 0.0 2.1 1 1 1 2 2 2 0 Surfeit locus protein 2 (SURF2) DUF3682 PF12446.3 ETN97620.1 - 7.6 6.8 12.9 12 6.1 8.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Peptidase_M43 PF05572.8 ETN97621.1 - 0.0028 17.2 3.1 0.0079 15.8 0.2 2.3 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A DUF1192 PF06698.6 ETN97621.1 - 1.1 9.0 7.8 1.8 8.4 0.0 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF1192) DUF4463 PF14703.1 ETN97622.1 - 0.017 15.6 0.4 0.059 13.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) Jiraiya PF15038.1 ETN97622.1 - 0.13 11.6 0.6 0.3 10.5 0.4 1.7 1 1 0 1 1 1 0 Jiraiya TPX2 PF06886.6 ETN97622.1 - 3.2 7.8 6.8 0.32 11.1 1.1 2.0 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) Sen15 PF09631.5 ETN97624.1 - 0.0091 16.2 0.0 0.011 15.8 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein Arrestin_C PF02752.17 ETN97625.1 - 0.067 13.3 1.2 0.12 12.4 0.8 1.4 1 1 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain BSP_II PF05432.6 ETN97625.1 - 2.8 7.1 13.7 3.9 6.6 9.5 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Macoilin PF09726.4 ETN97625.1 - 8.5 4.5 7.1 9.9 4.3 4.9 1.0 1 0 0 1 1 1 0 Transmembrane protein XH PF03469.9 ETN97626.1 - 0.013 15.1 3.8 0.39 10.3 0.0 2.2 2 0 0 2 2 2 0 XH domain Snf7 PF03357.16 ETN97626.1 - 0.067 12.5 6.6 0.025 13.9 2.4 1.8 2 0 0 2 2 2 0 Snf7 Retrotrans_gag PF03732.12 ETN97626.1 - 0.32 11.0 4.6 2.9 8.0 0.1 2.5 2 1 0 2 2 2 0 Retrotransposon gag protein HSDR_N PF04313.9 ETN97626.1 - 0.5 10.0 7.8 0.51 10.0 4.7 1.4 1 1 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Stirrup PF09061.1 ETN97627.1 - 0.047 13.6 3.0 2.2 8.2 0.0 2.8 2 1 1 3 3 3 0 Stirrup DUF4441 PF14536.1 ETN97627.1 - 1.1 9.2 10.8 0.17 11.8 2.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4441) SGT1 PF07093.6 ETN97628.1 - 0.00039 18.9 3.4 0.00043 18.8 2.4 1.0 1 0 0 1 1 1 1 SGT1 protein zf-C3HC4_3 PF13920.1 ETN97628.1 - 0.0031 17.1 0.5 0.005 16.4 0.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETN97628.1 - 0.009 15.8 0.8 0.016 15.0 0.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 ETN97628.1 - 0.074 12.7 0.5 0.12 12.0 0.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 ETN97628.1 - 0.13 12.3 0.6 0.25 11.3 0.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETN97628.1 - 0.13 11.9 0.8 0.24 11.0 0.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pentaxin PF00354.12 ETN97630.1 - 1.8 7.9 5.6 0.2 11.0 0.2 2.0 2 1 1 3 3 3 0 Pentaxin family RP-C PF03428.8 ETN97631.1 - 0.12 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Replication protein C N-terminal domain BBS2_C PF14782.1 ETN97633.1 - 0.12 10.9 8.7 0.12 10.9 6.0 1.0 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Hamartin PF04388.7 ETN97633.1 - 0.16 10.5 8.8 0.18 10.4 6.1 1.0 1 0 0 1 1 1 0 Hamartin protein Bud13 PF09736.4 ETN97633.1 - 0.27 11.4 10.4 0.31 11.3 7.2 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Gti1_Pac2 PF09729.4 ETN97633.1 - 0.3 10.9 3.5 0.33 10.8 2.4 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family MCPVI PF02993.9 ETN97633.1 - 0.43 10.6 11.6 0.5 10.4 8.0 1.1 1 0 0 1 1 1 0 Minor capsid protein VI Tim54 PF11711.3 ETN97633.1 - 0.44 9.0 6.4 0.48 8.9 4.5 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 USP8_interact PF08941.5 ETN97633.1 - 0.44 9.8 6.1 0.48 9.7 4.2 1.1 1 0 0 1 1 1 0 USP8 interacting LCD1 PF09798.4 ETN97633.1 - 0.69 7.8 19.8 0.65 7.9 13.8 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF106 PF01956.11 ETN97633.1 - 0.73 9.3 6.5 0.79 9.2 4.5 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 FimP PF09766.4 ETN97633.1 - 0.83 8.6 19.3 0.96 8.4 13.4 1.1 1 0 0 1 1 1 0 Fms-interacting protein eIF3_subunit PF08597.5 ETN97633.1 - 1.6 8.2 9.3 1.8 8.0 6.4 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit FAM60A PF15396.1 ETN97633.1 - 1.9 8.1 6.5 2.1 8.0 4.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A VIT1 PF01988.14 ETN97633.1 - 2.4 7.5 4.3 2.8 7.3 3.0 1.1 1 0 0 1 1 1 0 VIT family DUF702 PF05142.7 ETN97633.1 - 2.5 8.2 9.7 3 8.0 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF702) SIN1 PF05422.7 ETN97633.1 - 2.6 6.4 8.6 3.1 6.2 5.9 1.1 1 0 0 1 1 1 0 Stress-activated map kinase interacting protein 1 (SIN1) OmpH PF03938.9 ETN97633.1 - 2.8 7.8 28.4 3.3 7.6 19.7 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) eIF-3_zeta PF05091.7 ETN97633.1 - 2.8 6.4 12.8 3 6.3 8.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) V_ATPase_I PF01496.14 ETN97633.1 - 3 5.6 5.8 3.1 5.5 4.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PIH1 PF08190.7 ETN97633.1 - 3.1 7.1 16.3 3.6 6.9 11.3 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Mcm10 PF09332.6 ETN97633.1 - 3.2 6.9 12.6 4 6.6 8.8 1.1 1 0 0 1 1 1 0 Mcm10 replication factor TFIIA PF03153.8 ETN97633.1 - 3.5 7.4 25.3 3.8 7.3 17.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ctr PF04145.10 ETN97633.1 - 3.7 7.5 6.1 4.7 7.2 4.2 1.2 1 0 0 1 1 1 0 Ctr copper transporter family EIF4E-T PF10477.4 ETN97633.1 - 4.1 6.0 18.9 4.9 5.8 13.1 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Med15 PF09606.5 ETN97633.1 - 4.6 5.3 51.9 5 5.2 36.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal VID27 PF08553.5 ETN97633.1 - 5 5.2 8.0 5.6 5.0 5.5 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Pex16 PF08610.5 ETN97633.1 - 6 5.7 14.5 6.5 5.6 10.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Hid1 PF12722.2 ETN97633.1 - 7.9 4.0 13.8 8.9 3.8 9.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF775 PF05603.7 ETN97633.1 - 8 5.9 13.3 11 5.4 9.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Neur_chan_memb PF02932.11 ETN97633.1 - 8.5 6.1 7.0 9.6 6.0 4.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAT1 PF09770.4 ETN97633.1 - 9.2 4.3 40.5 9.5 4.3 28.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HEAT PF02985.17 ETN97634.1 - 4e-11 42.0 0.0 0.021 14.8 0.0 3.5 3 0 0 3 3 3 3 HEAT repeat HEAT_2 PF13646.1 ETN97634.1 - 5.8e-08 32.9 0.0 6.5e-05 23.1 0.0 2.4 1 1 1 2 2 2 2 HEAT repeats Cnd1 PF12717.2 ETN97634.1 - 2.4e-06 27.5 0.1 1.4e-05 25.0 0.1 2.3 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 ETN97634.1 - 9.7e-06 25.9 0.0 0.0041 17.5 0.0 2.9 1 1 2 3 3 3 2 HEAT-like repeat Gp-FAR-1 PF05823.7 ETN97634.1 - 8e-05 22.6 0.4 0.00014 21.8 0.3 1.4 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Vac14_Fab1_bd PF12755.2 ETN97634.1 - 0.001 19.3 0.2 0.2 12.0 0.0 2.6 1 1 2 3 3 3 1 Vacuolar 14 Fab1-binding region TAN PF11640.3 ETN97634.1 - 0.0011 18.7 6.4 0.0038 16.9 0.9 2.5 1 1 0 2 2 2 1 Telomere-length maintenance and DNA damage repair Proteasom_PSMB PF10508.4 ETN97634.1 - 0.0016 16.8 0.7 0.0026 16.1 0.5 1.4 1 1 0 1 1 1 1 Proteasome non-ATPase 26S subunit DUF3554 PF12074.3 ETN97634.1 - 0.034 13.5 1.0 0.61 9.4 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3554) UME PF08064.8 ETN97634.1 - 0.057 13.3 0.5 6.2 6.8 0.0 3.4 2 1 2 4 4 4 0 UME (NUC010) domain NLE PF08154.7 ETN97634.1 - 0.14 12.1 3.3 17 5.4 0.0 3.8 3 1 1 4 4 4 0 NLE (NUC135) domain IFRD PF05004.8 ETN97634.1 - 0.14 11.1 1.4 0.77 8.7 0.1 2.3 1 1 2 3 3 3 0 Interferon-related developmental regulator (IFRD) tRNA-synt_1g PF09334.6 ETN97635.1 - 2.4e-09 36.3 0.0 2.7e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 ETN97635.1 - 2.7e-09 35.6 0.0 3.1e-09 35.4 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) PH_3 PF14593.1 ETN97636.1 - 0.014 15.2 0.3 0.042 13.7 0.0 1.8 2 0 0 2 2 2 0 PH domain PH PF00169.24 ETN97636.1 - 0.035 14.3 2.6 0.082 13.1 0.1 2.3 2 0 0 2 2 2 0 PH domain HlyC PF02794.11 ETN97636.1 - 0.12 11.9 0.0 0.33 10.5 0.0 1.7 2 0 0 2 2 2 0 RTX toxin acyltransferase family Mucin PF01456.12 ETN97636.1 - 1.1 9.0 8.8 0.061 13.1 2.3 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein Vps53_N PF04100.7 ETN97637.1 - 0.0078 15.0 0.3 0.016 14.0 0.0 1.6 2 0 0 2 2 2 1 Vps53-like, N-terminal Bundlin PF05307.6 ETN97637.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Bundlin Kua-UEV1_localn PF10520.4 ETN97638.1 - 0.008 15.8 0.5 0.022 14.4 0.3 1.7 1 0 0 1 1 1 1 Kua-ubiquitin conjugating enzyme hybrid localisation domain Cyanate_lyase PF02560.9 ETN97638.1 - 0.12 11.8 0.0 0.44 10.1 0.0 1.9 2 0 0 2 2 2 0 Cyanate lyase C-terminal domain DUF948 PF06103.6 ETN97638.1 - 0.18 11.6 2.7 1.9 8.3 0.1 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) HAD_2 PF13419.1 ETN97639.1 - 3.1e-09 37.3 0.0 1.3e-08 35.2 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ETN97639.1 - 9.1e-06 25.3 0.0 2.4e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like ATS PF15445.1 ETN97639.1 - 0.016 14.3 1.2 0.02 14.0 0.8 1.3 1 0 0 1 1 1 0 acidic terminal segments, variant surface antigen of PfEMP1 DUF1504 PF07399.6 ETN97639.1 - 0.13 10.9 0.0 0.21 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1504) EF_assoc_1 PF08355.7 ETN97640.1 - 0.016 14.4 0.1 0.023 13.9 0.1 1.3 1 0 0 1 1 1 0 EF hand associated DUF4243 PF14027.1 ETN97641.1 - 0.04 13.3 2.7 3.6 6.9 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4243) RGS PF00615.14 ETN97641.1 - 0.083 13.0 1.4 0.17 12.0 0.9 1.4 1 1 0 1 1 1 0 Regulator of G protein signaling domain DUF3046 PF11248.3 ETN97642.1 - 0.0092 15.9 0.1 0.02 14.8 0.1 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3046) AlcCBM31 PF11606.3 ETN97642.1 - 0.031 14.2 0.1 0.053 13.4 0.1 1.4 1 0 0 1 1 1 0 Family 31 carbohydrate binding protein EBA-175_VI PF11556.3 ETN97642.1 - 0.098 12.7 2.8 0.23 11.6 1.9 1.6 1 1 0 1 1 1 0 Erythrocyte binding antigen 175 Ndufs5 PF10200.4 ETN97644.1 - 0.014 15.3 2.0 0.015 15.2 1.4 1.1 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa PX PF00787.19 ETN97645.1 - 2.7e-07 30.3 0.3 4e-07 29.8 0.2 1.3 1 0 0 1 1 1 1 PX domain Glyco_hydro_88 PF07470.8 ETN97648.1 - 0.0022 17.0 1.5 0.0028 16.7 1.0 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_transf_49 PF13896.1 ETN97649.1 - 2e-24 86.2 0.2 6.3e-24 84.6 0.2 1.8 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 ETN97649.1 - 9.7e-06 24.8 0.0 1.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 ETN97649.1 - 1.6e-05 24.6 0.0 4.1e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Pox_VLTF3 PF04947.9 ETN97649.1 - 0.075 12.5 0.1 0.1 12.0 0.1 1.2 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like N6_N4_Mtase PF01555.13 ETN97650.1 - 0.0057 16.1 0.0 0.0084 15.6 0.0 1.4 1 1 0 1 1 1 1 DNA methylase INCENP_ARK-bind PF03941.10 ETN97650.1 - 0.025 14.4 1.4 0.058 13.2 1.0 1.6 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region Rib_5-P_isom_A PF06026.9 ETN97650.1 - 0.069 12.4 0.4 0.11 11.7 0.3 1.2 1 0 0 1 1 1 0 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) VIGSSK PF14773.1 ETN97650.1 - 1.7 8.6 0.0 1.7 8.6 0.0 3.0 3 0 0 3 3 3 0 Helicase-associated putative binding domain, C-terminal TLD PF07534.11 ETN97651.1 - 6.9e-22 77.9 1.4 9.7e-22 77.4 1.0 1.2 1 0 0 1 1 1 1 TLD zf-TRAF PF02176.13 ETN97652.1 - 7.4e-05 23.0 6.6 7.4e-05 23.0 4.6 1.9 2 0 0 2 2 2 1 TRAF-type zinc finger TPR_MLP1_2 PF07926.7 ETN97652.1 - 0.0065 16.2 4.0 0.0065 16.2 2.8 2.9 3 0 0 3 3 3 2 TPR/MLP1/MLP2-like protein DUF972 PF06156.8 ETN97652.1 - 0.0072 16.6 1.7 0.0072 16.6 1.2 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF972) Bap31 PF05529.7 ETN97652.1 - 0.59 9.5 18.7 0.59 9.5 2.0 2.7 3 0 0 3 3 3 0 B-cell receptor-associated protein 31-like DUF641 PF04859.7 ETN97652.1 - 1.3 8.8 17.2 3.1 7.5 2.9 2.8 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF4279 PF14106.1 ETN97652.1 - 2 8.2 8.2 1.9 8.3 1.2 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4279) DUF342 PF03961.8 ETN97652.1 - 2.7 6.2 26.4 3 6.1 8.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Atg14 PF10186.4 ETN97652.1 - 3.1 6.6 24.2 2.5 6.9 6.2 2.4 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Geminin PF07412.7 ETN97652.1 - 5.3 6.6 24.9 0.14 11.8 3.5 3.4 3 2 0 3 3 3 0 Geminin TPD52 PF04201.10 ETN97652.1 - 8 6.1 16.4 2.5 7.7 2.7 2.8 2 1 1 3 3 3 0 Tumour protein D52 family Gly-zipper_Omp PF13488.1 ETN97653.1 - 4.8e-16 58.1 62.7 0.0071 15.9 2.0 6.7 2 1 0 2 2 2 1 Glycine zipper Gly-zipper_YMGG PF13441.1 ETN97653.1 - 7.5e-13 47.7 47.5 0.27 10.7 4.4 7.2 1 1 1 2 2 2 1 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.1 ETN97653.1 - 1.7e-05 24.4 46.7 0.34 10.5 3.5 5.8 1 1 4 5 5 5 4 Glycine-zipper containing OmpA-like membrane domain Bacteriocin_IIc PF10439.4 ETN97653.1 - 0.00023 21.2 76.1 1.5e+04 -55.8 52.7 7.6 1 1 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF456 PF04306.8 ETN97653.1 - 0.011 15.7 137.7 5.5 7.0 8.6 8.1 1 1 2 3 3 3 0 Protein of unknown function (DUF456) 7TM-7TMR_HD PF07698.6 ETN97653.1 - 8.8 5.7 67.1 1.8 7.9 8.1 4.3 1 1 3 4 4 4 0 7TM receptor with intracellular HD hydrolase ACOX PF01756.14 ETN97654.1 - 0.045 13.1 0.3 0.095 12.0 0.1 1.6 1 1 1 2 2 2 0 Acyl-CoA oxidase Poxvirus_B22R PF04395.7 ETN97654.1 - 0.047 13.1 0.8 0.062 12.8 0.6 1.3 1 1 0 1 1 1 0 Poxvirus B22R protein AAA PF00004.24 ETN97655.1 - 0.0016 18.6 0.2 0.0065 16.6 0.0 2.1 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Ribosomal_L17 PF01196.14 ETN97655.1 - 0.014 15.9 0.3 1.5 9.4 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein L17 AAA_22 PF13401.1 ETN97655.1 - 0.022 14.8 0.0 0.081 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 ETN97655.1 - 0.035 13.5 0.0 0.076 12.4 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MCM PF00493.18 ETN97655.1 - 0.043 12.6 0.0 0.096 11.4 0.0 1.5 1 0 0 1 1 1 0 MCM2/3/5 family ATP-synt_ab PF00006.20 ETN97655.1 - 0.047 13.1 0.2 0.096 12.1 0.1 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_tran PF00005.22 ETN97655.1 - 0.059 13.6 1.5 0.11 12.8 0.3 2.2 2 1 0 2 2 2 0 ABC transporter AAA_5 PF07728.9 ETN97655.1 - 0.073 12.8 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 ETN97655.1 - 0.23 11.7 9.7 0.57 10.4 2.1 3.1 1 1 1 2 2 2 0 AAA domain SPOUT_MTase PF02590.12 ETN97656.1 - 0.012 15.3 1.3 0.013 15.1 0.9 1.1 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase HTH_25 PF13413.1 ETN97656.1 - 0.014 14.9 0.1 0.03 13.9 0.1 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain Peptidase_C70 PF12385.3 ETN97656.1 - 0.032 13.9 0.1 0.039 13.6 0.0 1.1 1 0 0 1 1 1 0 Papain-like cysteine protease AvrRpt2 Peptidase_S58 PF03576.9 ETN97656.1 - 0.061 12.5 0.1 0.069 12.3 0.1 1.1 1 0 0 1 1 1 0 Peptidase family S58 Nit_Regul_Hom PF10126.4 ETN97656.1 - 0.077 12.7 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII DUF745 PF05335.8 ETN97656.1 - 0.37 10.2 5.8 0.45 10.0 3.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF745) Lipoprotein_20 PF13942.1 ETN97657.1 - 0.049 13.1 0.1 0.068 12.7 0.1 1.2 1 0 0 1 1 1 0 YfhG lipoprotein Aldolase_2 PF10120.4 ETN97658.1 - 0.062 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative aldolase RepB-RCR_reg PF10723.4 ETN97658.1 - 0.19 11.4 0.1 0.19 11.4 0.1 1.7 2 0 0 2 2 2 0 Replication regulatory protein RepB Glycoprotein_B PF00606.13 ETN97659.1 - 0.43 8.5 1.9 0.6 8.0 1.4 1.1 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B PKD PF00801.15 ETN97660.1 - 0.0059 16.3 0.3 0.013 15.1 0.2 1.5 1 0 0 1 1 1 1 PKD domain Na_H_antiport_2 PF13726.1 ETN97663.1 - 0.079 12.8 0.2 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Na+-H+ antiporter family YqaJ PF09588.5 ETN97664.1 - 4e-05 23.6 0.1 0.0059 16.5 0.0 2.4 2 0 0 2 2 2 2 YqaJ-like viral recombinase domain Pkinase PF00069.20 ETN97665.1 - 5.8e-39 133.8 0.0 8.7e-39 133.2 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETN97665.1 - 3.2e-15 55.8 0.0 6.9e-15 54.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETN97665.1 - 0.014 15.1 0.1 0.022 14.4 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 ETN97665.1 - 0.04 12.7 0.0 0.06 12.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase HSP70 PF00012.15 ETN97666.1 - 0.013 13.4 0.0 0.096 10.5 0.0 2.0 2 0 0 2 2 2 0 Hsp70 protein Hydantoinase_A PF01968.13 ETN97666.1 - 0.17 10.9 0.0 0.35 9.9 0.0 1.4 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Pkinase PF00069.20 ETN97667.1 - 8.2e-14 51.3 0.0 1.5e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETN97667.1 - 1.9e-05 23.9 0.3 0.0044 16.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase OmpH PF03938.9 ETN97667.1 - 9.1 6.1 11.4 18 5.2 7.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Pkinase PF00069.20 ETN97669.1 - 9.6e-19 67.5 0.0 1.9e-18 66.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETN97669.1 - 0.00016 20.8 0.0 0.00043 19.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase DUF3287 PF11690.3 ETN97669.1 - 0.07 13.1 0.7 0.12 12.4 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) CAP_GLY PF01302.20 ETN97670.1 - 0.00016 21.3 0.9 0.0015 18.2 0.6 2.4 1 1 0 1 1 1 1 CAP-Gly domain FUR PF01475.14 ETN97671.1 - 0.063 13.2 0.0 0.071 13.0 0.0 1.1 1 0 0 1 1 1 0 Ferric uptake regulator family zf-MIZ PF02891.15 ETN97671.1 - 0.14 11.7 0.5 0.19 11.2 0.4 1.3 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DUF4131 PF13567.1 ETN97672.1 - 0.54 9.6 2.0 7.5 5.9 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3366 PF11846.3 ETN97672.1 - 5.9 6.7 6.5 3.5 7.4 1.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3366) FHIPEP PF00771.15 ETN97672.1 - 6.8 4.8 10.8 3.2 5.9 5.7 1.7 2 0 0 2 2 2 0 FHIPEP family HEAT_2 PF13646.1 ETN97673.1 - 8.1e-05 22.8 0.0 0.01 16.1 0.0 2.5 1 1 0 1 1 1 1 HEAT repeats Dopey_N PF04118.9 ETN97673.1 - 0.00084 18.2 0.9 0.0071 15.1 0.6 2.7 1 1 0 1 1 1 1 Dopey, N-terminal HEAT_EZ PF13513.1 ETN97673.1 - 0.011 16.2 0.0 24 5.5 0.0 3.2 3 0 0 3 3 3 0 HEAT-like repeat HEAT PF02985.17 ETN97673.1 - 0.015 15.3 0.1 7.5 6.9 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat Cnd1 PF12717.2 ETN97673.1 - 0.019 14.8 1.0 0.068 13.0 0.3 1.9 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 zf-Tim10_DDP PF02953.10 ETN97674.1 - 0.014 14.6 0.5 0.044 13.0 0.3 1.9 1 0 0 1 1 1 0 Tim10/DDP family zinc finger ROS_MUCR PF05443.6 ETN97674.1 - 0.075 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein NACHT PF05729.7 ETN97675.1 - 2.7e-19 69.4 0.0 5e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETN97675.1 - 0.00058 19.8 0.0 0.0025 17.8 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 ETN97675.1 - 0.00088 18.2 1.6 0.0076 15.1 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_19 PF13245.1 ETN97675.1 - 0.0098 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 ETN97675.1 - 0.063 13.4 0.0 0.32 11.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 ETN97675.1 - 0.19 12.0 2.1 0.99 9.7 0.0 2.8 3 0 0 3 3 3 0 ABC transporter TRAP_alpha PF03896.11 ETN97675.1 - 0.29 10.1 8.3 0.52 9.2 5.7 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Daxx PF03344.10 ETN97675.1 - 0.86 8.0 17.5 1.3 7.4 12.2 1.3 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 ETN97675.1 - 0.88 8.2 14.3 1.5 7.4 9.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DRY_EERY PF09750.4 ETN97675.1 - 2.4 8.2 12.6 1.3 9.1 7.1 1.7 1 1 0 1 1 1 0 Alternative splicing regulator Zip PF02535.17 ETN97675.1 - 3.4 6.5 6.4 5 6.0 4.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CobT PF06213.7 ETN97675.1 - 4.6 6.2 15.2 8.8 5.3 10.5 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT GIT_SHD PF08518.6 ETN97675.1 - 4.9 6.6 5.2 1.3 8.4 0.9 2.0 3 0 0 3 3 3 0 Spa2 homology domain (SHD) of GIT RdRP PF05183.7 ETN97678.1 - 0.0019 16.9 0.6 0.0023 16.7 0.0 1.4 2 0 0 2 2 2 1 RNA dependent RNA polymerase DUF972 PF06156.8 ETN97678.1 - 0.084 13.2 2.5 0.12 12.6 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) CH PF00307.26 ETN97679.1 - 6e-21 74.5 0.4 2.9e-12 46.5 0.1 2.1 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 ETN97679.1 - 0.00023 20.7 0.0 0.00041 19.9 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain DivIVA PF05103.8 ETN97680.1 - 0.001 19.1 7.1 0.017 15.1 0.3 2.4 2 0 0 2 2 2 2 DivIVA protein RNase_Zc3h12a_2 PF14626.1 ETN97680.1 - 0.12 12.2 1.4 0.22 11.3 0.4 1.9 2 0 0 2 2 2 0 Zc3h12a-like Ribonuclease NYN domain Phasin_2 PF09361.5 ETN97680.1 - 0.19 11.7 1.6 0.35 10.9 0.3 2.0 2 0 0 2 2 2 0 Phasin protein Occludin_ELL PF07303.8 ETN97680.1 - 1.2 9.9 5.4 6.3 7.6 0.4 2.8 1 1 1 2 2 2 0 Occludin homology domain Helitron_like_N PF14214.1 ETN97681.1 - 0.027 14.1 1.9 0.043 13.5 1.3 1.3 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus YjgP_YjgQ PF03739.9 ETN97681.1 - 0.95 8.1 3.6 1.3 7.6 2.5 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF4028 PF13220.1 ETN97683.1 - 0.0054 16.3 2.2 0.044 13.4 0.1 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF4028) PINIT PF14324.1 ETN97683.1 - 0.031 14.3 1.4 0.044 13.8 0.9 1.2 1 0 0 1 1 1 0 PINIT domain GLTSCR1 PF15249.1 ETN97683.1 - 0.041 13.9 0.2 0.72 9.9 0.0 2.1 2 0 0 2 2 2 0 Glioma tumor suppressor candidate region TFIIE_alpha PF02002.12 ETN97683.1 - 0.099 12.1 0.3 0.88 9.1 0.0 2.0 2 0 0 2 2 2 0 TFIIE alpha subunit CLASP_N PF12348.3 ETN97683.1 - 0.69 9.2 4.6 8.4 5.6 0.6 2.2 1 1 1 2 2 2 0 CLASP N terminal Herpes_U30 PF04523.8 ETN97687.1 - 0.082 10.3 0.1 0.088 10.2 0.1 1.0 1 0 0 1 1 1 0 Herpes virus tegument protein U30 AAA_11 PF13086.1 ETN97687.1 - 0.11 12.0 3.3 0.11 11.9 2.3 1.1 1 0 0 1 1 1 0 AAA domain SMN PF06003.7 ETN97687.1 - 0.83 8.6 6.2 1.1 8.2 4.3 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DUF1875 PF08961.5 ETN97687.1 - 1.5 8.0 7.2 1.7 7.9 5.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) SR-25 PF10500.4 ETN97687.1 - 3.5 7.0 15.4 4.2 6.7 10.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TPR_12 PF13424.1 ETN97688.1 - 8.3e-109 355.6 34.2 1.1e-23 82.9 3.4 6.6 4 2 3 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.1 ETN97688.1 - 1.8e-53 177.0 0.0 5.3e-07 29.3 0.1 10.1 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_1 PF00515.23 ETN97688.1 - 1.6e-52 173.0 51.4 9.7e-07 28.1 1.1 10.7 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_11 PF13414.1 ETN97688.1 - 2.3e-51 171.3 40.0 2.9e-12 46.0 0.2 7.4 3 2 4 9 9 9 8 TPR repeat TPR_2 PF07719.12 ETN97688.1 - 1e-44 146.8 38.9 1.2e-05 24.8 0.8 10.6 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_7 PF13176.1 ETN97688.1 - 5.6e-41 135.1 21.3 2e-06 27.1 0.1 10.4 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_8 PF13181.1 ETN97688.1 - 3.4e-32 107.7 59.0 2.5e-05 23.7 0.3 11.2 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_16 PF13432.1 ETN97688.1 - 6.6e-17 61.6 0.1 0.00083 19.9 0.2 6.8 5 2 2 7 7 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 ETN97688.1 - 8.5e-17 59.8 16.8 0.06 13.5 0.0 10.3 10 1 0 10 10 9 4 Tetratricopeptide repeat Apc3 PF12895.2 ETN97688.1 - 1.7e-11 44.0 29.8 0.00038 20.5 4.8 6.3 2 1 4 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 ETN97688.1 - 1.8e-10 40.4 0.0 3.2 8.6 0.0 7.7 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETN97688.1 - 4.3e-09 36.2 12.3 10 6.8 0.0 9.2 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETN97688.1 - 8.3e-06 26.0 12.2 0.27 11.6 0.2 6.3 4 2 3 7 7 6 3 Tetratricopeptide repeat PPR PF01535.15 ETN97688.1 - 2e-05 24.2 9.2 0.5 10.4 0.0 6.2 5 0 0 5 5 5 1 PPR repeat Fis1_TPR_C PF14853.1 ETN97688.1 - 0.00059 19.6 34.9 0.098 12.5 0.4 9.1 9 1 1 10 10 10 2 Fis1 C-terminal tetratricopeptide repeat DUF627 PF04781.7 ETN97688.1 - 0.00097 18.7 21.3 0.34 10.5 0.0 7.2 6 3 2 8 8 7 1 Protein of unknown function (DUF627) DUF2977 PF11192.3 ETN97688.1 - 0.0017 18.1 0.2 33 4.4 0.0 4.7 5 0 0 5 5 4 0 Protein of unknown function (DUF2977) TPR_3 PF07720.7 ETN97688.1 - 0.0025 17.5 33.0 0.022 14.5 1.0 6.4 7 0 0 7 7 5 2 Tetratricopeptide repeat Peptidase_C53 PF05550.6 ETN97688.1 - 0.019 14.4 1.0 0.88 9.0 0.1 2.4 2 0 0 2 2 2 0 Pestivirus Npro endopeptidase C53 MIT PF04212.13 ETN97688.1 - 0.11 12.3 39.6 1.9 8.4 0.1 8.7 8 1 1 10 10 10 0 MIT (microtubule interacting and transport) domain Phage_Treg PF04761.7 ETN97688.1 - 0.31 10.8 13.0 6 6.7 0.1 5.1 4 1 1 5 5 5 0 Lactococcus bacteriophage putative transcription regulator Rep_3 PF01051.16 ETN97688.1 - 0.38 10.3 7.5 0.17 11.4 2.0 2.6 3 2 0 3 3 3 0 Initiator Replication protein SHNi-TPR PF10516.4 ETN97688.1 - 1.8 7.8 11.2 8.2 5.7 0.0 5.9 8 0 0 8 8 8 0 SHNi-TPR Ret_tiss PF10044.4 ETN97689.1 - 0.073 13.6 6.8 1.3 9.5 0.1 3.7 2 1 3 5 5 5 0 Retinal tissue protein RadC PF04002.10 ETN97689.1 - 0.36 10.5 3.6 2.1 8.0 0.1 2.9 2 1 1 3 3 3 0 RadC-like JAB domain Kelch_1 PF01344.20 ETN97690.1 - 0.00019 20.9 0.3 0.0024 17.3 0.2 2.2 2 0 0 2 2 2 1 Kelch motif PC4 PF02229.11 ETN97690.1 - 0.00099 18.2 1.0 0.0018 17.4 0.3 1.6 2 0 0 2 2 2 1 Transcriptional Coactivator p15 (PC4) Kelch_6 PF13964.1 ETN97690.1 - 0.0023 18.0 0.5 0.27 11.4 0.2 2.2 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.10 ETN97690.1 - 0.012 15.3 0.2 0.55 10.0 0.2 2.4 2 0 0 2 2 2 0 Kelch motif Kelch_5 PF13854.1 ETN97690.1 - 0.013 15.4 0.4 0.086 12.8 0.1 2.1 2 0 0 2 2 2 0 Kelch motif DUF1955 PF09205.5 ETN97690.1 - 0.028 13.9 2.5 0.037 13.5 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) Alpha-amyl_C2 PF07821.7 ETN97690.1 - 0.092 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Alpha-amylase C-terminal beta-sheet domain PBP_dimer PF03717.10 ETN97692.1 - 0.023 14.7 0.8 0.038 14.0 0.5 1.4 1 0 0 1 1 1 0 Penicillin-binding Protein dimerisation domain DUF240 PF03086.9 ETN97693.1 - 0.13 11.9 1.5 0.28 10.8 0.2 2.1 1 1 1 2 2 2 0 MG032/MG096/MG288 family 2 Ank_4 PF13637.1 ETN97694.1 - 1.3e-08 35.1 1.2 2.2e-06 28.0 0.3 2.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 ETN97694.1 - 5.6e-07 29.0 1.6 0.061 13.1 0.1 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 ETN97694.1 - 3.8e-06 27.1 2.6 0.0044 17.3 0.4 3.0 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETN97694.1 - 9.7e-06 25.3 1.8 1.7 9.1 0.1 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 ETN97694.1 - 0.037 14.2 4.2 0.96 9.7 0.2 3.5 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETN97695.1 - 3.2e-05 24.0 0.1 0.26 11.6 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETN97695.1 - 6.8e-05 23.1 0.1 0.053 13.8 0.0 2.9 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETN97695.1 - 0.00018 21.1 0.2 0.14 12.0 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 ETN97695.1 - 0.0002 21.7 0.1 0.023 15.2 0.0 3.0 2 2 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETN97695.1 - 0.0053 16.8 2.2 1.7 9.1 0.0 4.3 5 0 0 5 5 5 1 Ankyrin repeat DUF1539 PF07560.6 ETN97696.1 - 0.057 13.2 0.9 0.094 12.5 0.3 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) DivIC PF04977.10 ETN97697.1 - 0.11 12.0 1.1 0.33 10.4 0.7 1.9 1 0 0 1 1 1 0 Septum formation initiator DUF342 PF03961.8 ETN97697.1 - 1.4 7.2 9.6 1.4 7.2 6.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Mnd1 PF03962.10 ETN97697.1 - 2.6 7.6 14.9 1.1 8.8 7.1 1.9 1 1 1 2 2 2 0 Mnd1 family Vfa1 PF08432.5 ETN97697.1 - 3.3 7.6 15.2 4 7.4 10.5 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Kelch_1 PF01344.20 ETN97700.1 - 7.8e-07 28.5 1.6 0.023 14.2 0.1 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETN97700.1 - 2.6e-05 24.1 3.3 0.61 10.3 0.1 4.0 3 1 1 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETN97700.1 - 0.00088 18.9 0.0 2.5 7.9 0.0 3.0 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETN97700.1 - 0.013 15.2 2.8 1.5 8.7 0.1 3.8 4 0 0 4 4 4 0 Kelch motif SYCE1 PF15233.1 ETN97701.1 - 0.15 11.9 6.8 0.23 11.3 4.7 1.3 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 UN_NPL4 PF11543.3 ETN97702.1 - 0.093 13.0 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Choline_sulf_C PF12411.3 ETN97702.1 - 6.9 6.5 5.8 1.1 9.1 0.1 2.4 3 0 0 3 3 3 0 Choline sulfatase enzyme C terminal WD40 PF00400.27 ETN97703.1 - 1.3e-77 253.1 16.8 1.3e-12 47.0 0.0 7.0 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETN97703.1 - 6.9e-11 42.2 0.0 2.9e-05 23.8 0.0 3.5 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETN97703.1 - 2.2e-06 27.1 12.1 11 5.8 0.0 6.9 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETN97703.1 - 3e-06 25.8 0.3 0.00082 17.7 0.0 2.3 1 1 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.3 ETN97703.1 - 2.1e-05 22.8 3.2 0.15 10.1 0.1 3.9 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF1258 PF06869.7 ETN97703.1 - 6.3e-05 22.1 1.9 0.097 11.7 0.1 3.5 2 1 2 4 4 4 2 Protein of unknown function (DUF1258) Coatomer_WDAD PF04053.9 ETN97703.1 - 0.00016 20.6 0.0 0.0069 15.2 0.0 2.3 1 1 1 2 2 2 2 Coatomer WD associated region SGL PF08450.7 ETN97703.1 - 0.00026 20.4 0.1 0.064 12.6 0.0 3.3 1 1 3 4 4 4 1 SMP-30/Gluconolaconase/LRE-like region Nbas_N PF15492.1 ETN97703.1 - 0.0014 17.7 0.2 2.6 7.0 0.0 3.0 1 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 ETN97703.1 - 0.0062 16.0 0.0 0.055 12.9 0.0 2.1 1 1 0 1 1 1 1 PQQ-like domain NYD-SP28_assoc PF14775.1 ETN97703.1 - 0.0084 15.7 2.3 20 4.9 0.0 5.6 7 0 0 7 7 7 0 Sperm tail C-terminal domain DPPIV_N PF00930.16 ETN97703.1 - 0.021 13.4 0.1 3.5 6.1 0.0 3.2 3 1 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Me-amine-dh_H PF06433.6 ETN97703.1 - 0.027 13.1 0.0 0.075 11.6 0.0 1.6 1 1 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) Proteasome_A_N PF10584.4 ETN97703.1 - 0.062 12.6 3.2 59 3.1 0.0 4.9 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Cys_rich_VLP PF14194.1 ETN97704.1 - 0.0034 17.0 2.9 0.0062 16.2 2.0 1.5 1 0 0 1 1 1 1 Cysteine-rich VLP Nucleoplasmin PF03066.10 ETN97706.1 - 0.06 12.8 3.3 0.084 12.3 2.3 1.2 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 ETN97706.1 - 1.4 9.2 7.2 2.8 8.3 5.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.4 ETN97706.1 - 7 5.2 9.5 9.7 4.7 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Peptidase_C1 PF00112.18 ETN97707.1 - 1.7e-55 188.2 5.2 1.9e-55 188.1 3.6 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 ETN97707.1 - 0.00054 18.6 0.2 0.00074 18.1 0.1 1.1 1 0 0 1 1 1 1 Peptidase C1-like family MTHFR_C PF12225.3 ETN97707.1 - 0.12 11.9 3.1 1.5 8.3 0.2 2.5 2 0 0 2 2 2 0 Methylene-tetrahydrofolate reductase C terminal SirB PF04247.7 ETN97708.1 - 0.083 12.6 11.0 0.31 10.7 6.7 2.0 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB Lumazine_bd PF12870.2 ETN97709.1 - 1.2 9.1 7.2 0.19 11.7 1.4 2.1 1 1 1 2 2 2 0 Lumazine-binding domain Sed5p PF11416.3 ETN97709.1 - 2.4 7.6 9.4 1.3 8.5 1.9 3.0 2 1 0 2 2 2 0 Integral membrane protein Sed5p DUF1764 PF08576.5 ETN97710.1 - 0.2 12.4 3.8 0.24 12.2 2.6 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) ATP-synt_E PF05680.7 ETN97710.1 - 2.1 8.3 6.1 2.4 8.1 4.2 1.2 1 0 0 1 1 1 0 ATP synthase E chain zf-TRAF PF02176.13 ETN97711.1 - 7.7e-06 26.1 2.4 2.4e-05 24.6 1.6 1.8 1 0 0 1 1 1 1 TRAF-type zinc finger Gp58 PF07902.6 ETN97711.1 - 0.025 12.8 10.6 0.025 12.8 6.8 1.3 1 1 0 1 1 1 0 gp58-like protein PMT_C PF11647.3 ETN97711.1 - 0.06 12.9 1.1 0.06 12.9 0.8 2.3 2 1 0 2 2 2 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 TACC PF05010.9 ETN97711.1 - 1.1 8.9 28.3 0.41 10.3 14.5 2.1 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) DUF2968 PF11180.3 ETN97711.1 - 1.9 7.8 16.7 0.37 10.1 8.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) TPR_12 PF13424.1 ETN97713.1 - 1.3e-22 79.4 0.7 3e-22 78.3 0.5 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETN97713.1 - 1.3e-19 68.9 10.1 1.1e-09 37.4 0.5 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETN97713.1 - 2.3e-16 59.1 4.7 2.8e-16 58.8 2.4 1.8 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 ETN97713.1 - 4e-16 57.5 5.5 1.7e-07 30.5 0.8 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETN97713.1 - 1e-14 53.0 0.3 8.2e-07 28.3 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETN97713.1 - 1.6e-14 53.2 0.0 6.4e-07 29.0 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETN97713.1 - 3e-13 48.5 9.8 7.4e-07 28.5 0.5 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETN97713.1 - 4.4e-07 29.5 3.0 0.0011 18.9 0.4 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETN97713.1 - 3.2e-06 27.2 0.7 0.022 15.2 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_3 PF07720.7 ETN97713.1 - 3.9e-06 26.5 2.3 0.0058 16.4 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.13 ETN97713.1 - 4.1e-06 26.5 3.6 0.028 14.2 0.1 2.4 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain TPR_16 PF13432.1 ETN97713.1 - 6.6e-06 26.6 0.0 1.2e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETN97713.1 - 2.6e-05 23.3 0.0 0.043 13.0 0.0 2.4 2 0 0 2 2 2 2 SHNi-TPR SNAP PF14938.1 ETN97713.1 - 0.00024 20.3 1.2 0.0004 19.6 0.9 1.3 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_14 PF13428.1 ETN97713.1 - 0.00033 21.0 0.0 0.43 11.3 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETN97713.1 - 0.0022 18.3 0.5 0.58 10.5 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 ETN97713.1 - 0.0076 16.3 3.2 0.022 14.9 2.1 1.9 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.2 ETN97713.1 - 0.02 14.7 0.5 0.32 10.8 0.2 2.5 2 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) DUF627 PF04781.7 ETN97713.1 - 0.038 13.6 0.8 0.24 11.0 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF627) Sec5 PF15469.1 ETN97713.1 - 0.043 13.5 0.4 0.043 13.5 0.3 2.3 2 1 0 2 2 2 0 Exocyst complex component Sec5 Sel1 PF08238.7 ETN97713.1 - 0.13 12.9 1.4 13 6.6 0.1 2.4 2 0 0 2 2 2 0 Sel1 repeat GHL1-3 PF11308.3 ETN97713.1 - 1.1 8.5 4.7 0.51 9.6 0.1 2.3 2 1 1 3 3 3 0 Glycosyl hydrolases related to GH101 family, GHL1-GHL3 PH_10 PF15411.1 ETN97714.1 - 0.092 12.9 5.7 0.089 12.9 3.5 1.2 1 1 0 1 1 1 0 Pleckstrin homology domain Kri1 PF05178.7 ETN97714.1 - 4.7 7.5 6.9 8.2 6.7 4.8 1.4 1 1 0 1 1 1 0 KRI1-like family DUF3538 PF12057.3 ETN97715.1 - 0.077 12.6 0.3 0.18 11.4 0.1 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3538) Sec3_C PF09763.4 ETN97715.1 - 0.43 8.6 7.2 0.49 8.4 5.0 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 SR-25 PF10500.4 ETN97715.1 - 8.5 5.7 10.8 15 5.0 7.5 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ycf1 PF05758.7 ETN97717.1 - 1.1e-05 23.4 0.9 1.2e-05 23.2 0.6 1.1 1 0 0 1 1 1 1 Ycf1 DUF2828 PF11443.3 ETN97717.1 - 0.0043 15.3 4.5 0.0058 14.8 3.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) FRG1 PF06229.7 ETN97717.1 - 0.025 14.0 11.6 0.044 13.2 8.0 1.3 1 0 0 1 1 1 0 FRG1-like family DDHD PF02862.12 ETN97717.1 - 0.46 10.2 7.6 0.76 9.5 5.3 1.3 1 0 0 1 1 1 0 DDHD domain AAA_23 PF13476.1 ETN97717.1 - 5 7.4 20.5 0.96 9.7 11.2 1.9 2 0 0 2 2 2 0 AAA domain CAF-1_p150 PF11600.3 ETN97717.1 - 6.7 6.0 35.7 0.036 13.4 18.6 1.7 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Peptidase_U57 PF05582.7 ETN97717.1 - 8.9 5.1 10.7 16 4.3 7.4 1.3 1 0 0 1 1 1 0 YabG peptidase U57 WD40 PF00400.27 ETN97718.1 - 3.5e-09 36.2 0.7 6.3e-09 35.3 0.5 1.5 1 0 0 1 1 1 1 WD domain, G-beta repeat DUF641 PF04859.7 ETN97718.1 - 0.004 16.9 15.4 0.19 11.5 1.4 2.4 2 0 0 2 2 2 2 Plant protein of unknown function (DUF641) Bap31 PF05529.7 ETN97718.1 - 0.15 11.4 21.7 2.1e+02 1.2 15.0 2.3 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like HSCB_C PF07743.8 ETN97718.1 - 0.31 11.5 15.3 1.5 9.3 2.9 2.9 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain TPR_MLP1_2 PF07926.7 ETN97718.1 - 0.56 9.9 25.9 2.1 8.1 6.6 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.6 ETN97718.1 - 1.1 9.0 24.9 3.2 7.5 17.3 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Geminin PF07412.7 ETN97718.1 - 1.4 8.5 20.6 0.13 11.9 4.4 2.8 1 1 1 2 2 2 0 Geminin DUF3735 PF12537.3 ETN97718.1 - 2 8.5 5.1 0.77 9.8 0.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3735) GvpL_GvpF PF06386.6 ETN97718.1 - 3 7.3 12.2 14 5.2 8.5 1.8 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF972 PF06156.8 ETN97718.1 - 3.6 7.9 23.4 0.43 10.9 5.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TPD52 PF04201.10 ETN97718.1 - 5.6 6.6 14.3 0.48 10.1 2.3 2.5 2 1 0 2 2 2 0 Tumour protein D52 family BioW PF03744.8 ETN97718.1 - 6 6.2 10.5 2.9 7.2 5.8 1.5 1 1 0 1 1 1 0 6-carboxyhexanoate--CoA ligase DUF1764 PF08576.5 ETN97718.1 - 6.7 7.5 11.8 0.86 10.4 3.7 2.0 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) bZIP_1 PF00170.16 ETN97718.1 - 7.7 6.5 16.4 4.2 7.4 0.5 3.4 2 1 1 3 3 3 0 bZIP transcription factor Atg14 PF10186.4 ETN97718.1 - 8.3 5.2 24.2 1.9 7.3 3.1 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 SAM_1 PF00536.25 ETN97719.1 - 7.9e-13 48.3 0.3 1.4e-12 47.6 0.2 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETN97719.1 - 1e-10 41.2 0.2 1.5e-10 40.7 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) TFIIE_alpha PF02002.12 ETN97719.1 - 0.051 13.0 0.8 0.072 12.5 0.6 1.2 1 0 0 1 1 1 0 TFIIE alpha subunit CDC45 PF02724.9 ETN97721.1 - 0.024 12.6 4.6 0.034 12.1 3.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2413 PF10310.4 ETN97721.1 - 0.035 12.9 8.3 0.049 12.4 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF1510 PF07423.6 ETN97721.1 - 0.17 11.2 11.2 0.3 10.4 7.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) LMBR1 PF04791.11 ETN97721.1 - 0.24 9.9 1.9 0.27 9.7 1.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein ADIP PF11559.3 ETN97723.1 - 0.0059 16.5 17.4 0.0059 16.5 12.1 2.1 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding IFT57 PF10498.4 ETN97723.1 - 0.013 14.2 22.3 0.016 13.9 15.5 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Myosin_tail_1 PF01576.14 ETN97723.1 - 0.017 12.8 27.6 0.031 11.9 19.1 1.4 1 1 0 1 1 1 0 Myosin tail SH3BP5 PF05276.9 ETN97723.1 - 0.023 14.0 16.5 0.027 13.8 11.4 1.1 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) Tropomyosin_1 PF12718.2 ETN97723.1 - 0.027 14.3 31.1 0.14 12.0 21.6 2.0 1 1 0 1 1 1 0 Tropomyosin like Reo_sigmaC PF04582.7 ETN97723.1 - 0.038 13.1 3.9 0.042 13.0 2.7 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein ATG16 PF08614.6 ETN97723.1 - 0.069 12.9 24.6 0.074 12.8 17.0 1.0 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) PilJ PF13675.1 ETN97723.1 - 0.09 13.0 9.3 0.2 11.9 6.4 1.7 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term SusD-like_3 PF14322.1 ETN97723.1 - 0.096 12.7 5.1 0.047 13.7 1.6 1.6 1 1 0 1 1 1 0 Starch-binding associating with outer membrane YscO PF07321.7 ETN97723.1 - 0.11 12.2 25.2 0.05 13.4 15.3 1.8 1 1 1 2 2 2 0 Type III secretion protein YscO Fmp27_WPPW PF10359.4 ETN97723.1 - 0.12 10.7 18.7 0.14 10.5 13.0 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain CENP-F_leu_zip PF10473.4 ETN97723.1 - 0.13 12.0 30.7 0.6 9.9 20.0 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Acyl-CoA_dh_2 PF08028.6 ETN97723.1 - 0.17 12.1 4.4 0.21 11.8 3.0 1.2 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain DUF869 PF05911.6 ETN97723.1 - 0.17 10.0 27.5 0.19 9.9 19.1 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) DAHP_synth_2 PF01474.11 ETN97723.1 - 0.23 9.7 7.2 0.26 9.5 5.0 1.1 1 0 0 1 1 1 0 Class-II DAHP synthetase family DUF3080 PF11279.3 ETN97723.1 - 0.29 10.2 13.8 0.37 9.8 9.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) Spc7 PF08317.6 ETN97723.1 - 0.31 9.6 26.5 0.41 9.2 18.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CALCOCO1 PF07888.6 ETN97723.1 - 0.32 9.2 22.3 0.36 9.0 15.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Cytokin-bind PF09265.5 ETN97723.1 - 0.38 9.8 5.5 0.54 9.3 3.8 1.3 1 1 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding DUF1664 PF07889.7 ETN97723.1 - 0.47 10.2 14.8 0.11 12.2 4.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) LAGLIDADG_WhiA PF14527.1 ETN97723.1 - 0.54 10.1 3.8 0.77 9.6 2.6 1.4 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain TMCO5 PF14992.1 ETN97723.1 - 0.62 9.1 23.6 0.72 8.9 16.4 1.2 1 0 0 1 1 1 0 TMCO5 family FliD_C PF07195.7 ETN97723.1 - 0.64 9.2 14.6 0.33 10.2 8.8 1.6 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Lyase_8_N PF08124.6 ETN97723.1 - 0.65 8.8 10.4 0.77 8.5 7.2 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain Atg14 PF10186.4 ETN97723.1 - 0.66 8.8 23.8 0.83 8.5 16.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HemX PF04375.9 ETN97723.1 - 0.71 8.4 22.5 1.2 7.6 15.6 1.4 1 1 0 1 1 1 0 HemX TPR_MLP1_2 PF07926.7 ETN97723.1 - 0.72 9.6 34.9 1.2 8.9 11.6 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3552 PF12072.3 ETN97723.1 - 0.8 8.8 31.8 0.035 13.3 11.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) TMPIT PF07851.8 ETN97723.1 - 0.81 8.6 16.6 0.6 9.1 10.7 1.4 1 1 0 1 1 1 0 TMPIT-like protein Herpes_UL6 PF01763.11 ETN97723.1 - 0.83 7.7 11.2 0.98 7.5 7.8 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Pox_F11 PF04943.7 ETN97723.1 - 0.9 8.3 7.7 0.91 8.3 5.3 1.1 1 0 0 1 1 1 0 Poxvirus F11 protein TMF_DNA_bd PF12329.3 ETN97723.1 - 1 9.2 35.5 0.022 14.5 13.8 3.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding USP8_interact PF08941.5 ETN97723.1 - 1.1 8.5 9.0 0.93 8.7 5.5 1.5 1 1 0 1 1 1 0 USP8 interacting HOOK PF05622.7 ETN97723.1 - 1.2 6.8 28.4 0.17 9.6 9.7 2.0 1 1 1 2 2 2 0 HOOK protein GAS PF13851.1 ETN97723.1 - 1.2 8.2 31.0 2.9 7.0 21.5 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 ETN97723.1 - 1.3 9.3 26.1 1.2 9.4 5.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Exonuc_VII_L PF02601.10 ETN97723.1 - 1.5 7.9 18.6 1.6 7.8 12.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fib_alpha PF08702.5 ETN97723.1 - 1.7 8.7 21.3 0.38 10.8 8.6 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Tweety PF04906.8 ETN97723.1 - 1.7 6.9 8.7 1.9 6.8 6.1 1.2 1 0 0 1 1 1 0 Tweety HlyD PF00529.15 ETN97723.1 - 1.7 7.8 15.5 2.1 7.5 10.7 1.2 1 0 0 1 1 1 0 HlyD family secretion protein DUF342 PF03961.8 ETN97723.1 - 1.9 6.8 19.4 2.1 6.6 13.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) WXG100 PF06013.7 ETN97723.1 - 2 8.4 18.2 0.55 10.2 6.9 3.2 1 1 0 2 2 2 0 Proteins of 100 residues with WXG DUF724 PF05266.9 ETN97723.1 - 2.1 7.9 23.5 1.3 8.6 14.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) UPF0184 PF03670.8 ETN97723.1 - 2.2 8.4 11.4 8.2 6.6 0.3 3.2 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0184) AAA_13 PF13166.1 ETN97723.1 - 2.3 6.5 23.8 2.5 6.4 16.5 1.0 1 0 0 1 1 1 0 AAA domain NPV_P10 PF05531.7 ETN97723.1 - 2.4 8.4 11.3 89 3.4 7.8 2.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein FTCD_C PF04961.7 ETN97723.1 - 2.5 7.4 9.9 3.9 6.8 6.9 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase DUF2730 PF10805.3 ETN97723.1 - 2.6 7.8 12.6 1 9.1 6.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) DUF2803 PF10972.3 ETN97723.1 - 2.7 7.4 11.1 4.2 6.8 7.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2803) RmuC PF02646.11 ETN97723.1 - 2.7 6.7 20.1 0.16 10.7 8.9 1.9 1 1 1 2 2 2 0 RmuC family IncA PF04156.9 ETN97723.1 - 2.7 7.5 28.0 12 5.3 19.4 1.9 1 1 0 1 1 1 0 IncA protein COG2 PF06148.6 ETN97723.1 - 2.9 7.7 17.2 0.63 9.9 5.7 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3584 PF12128.3 ETN97723.1 - 3.1 4.9 27.1 3.7 4.7 18.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Seryl_tRNA_N PF02403.17 ETN97723.1 - 3.2 7.8 25.2 0.57 10.2 13.9 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Sec20 PF03908.8 ETN97723.1 - 3.3 7.4 13.3 2.2 8.0 0.3 2.8 1 1 2 3 3 3 0 Sec20 Allexi_40kDa PF05549.6 ETN97723.1 - 4.1 6.6 11.2 4.7 6.4 7.8 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Mod_r PF07200.8 ETN97723.1 - 4.2 7.2 29.1 6 6.7 11.8 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF4298 PF14131.1 ETN97723.1 - 4.2 7.3 14.1 0.2 11.5 2.5 2.6 3 1 0 3 3 2 0 Domain of unknown function (DUF4298) Laminin_II PF06009.7 ETN97723.1 - 5.3 6.7 19.8 1.2 8.8 8.1 2.1 1 1 1 2 2 2 0 Laminin Domain II Syntaxin-6_N PF09177.6 ETN97723.1 - 5.4 7.4 16.6 5.9 7.3 8.4 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal ERM PF00769.14 ETN97723.1 - 6.9 6.1 34.0 1.5 8.3 9.8 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family ZYG-11_interact PF05884.7 ETN97723.1 - 7 5.6 6.5 7.8 5.4 4.5 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 DUF4200 PF13863.1 ETN97723.1 - 7.8 6.4 34.0 1.7 8.6 15.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF4407 PF14362.1 ETN97723.1 - 7.9 5.3 15.9 2.7 6.8 9.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) MotA_ExbB PF01618.11 ETN97723.1 - 8 6.0 8.6 11 5.6 5.5 1.8 1 1 0 1 1 1 0 MotA/TolQ/ExbB proton channel family Mit_KHE1 PF10173.4 ETN97723.1 - 8.4 6.2 13.0 9.4 6.0 9.0 1.1 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Metal_resist PF13801.1 ETN97723.1 - 8.5 6.3 11.2 0.77 9.7 3.5 1.9 1 1 1 2 2 2 0 Heavy-metal resistance AbiH PF14253.1 ETN97723.1 - 9.1 5.7 10.7 10 5.6 7.4 1.1 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH YjcZ PF13990.1 ETN97723.1 - 9.3 5.2 15.9 1.5 7.9 6.8 1.9 1 1 1 2 2 2 0 YjcZ-like protein AAA_9 PF12781.2 ETN97725.1 - 9.3e-36 122.7 0.1 1.5e-35 122.1 0.1 1.3 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 ETN97725.1 - 9.1e-10 37.8 0.0 1.8e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor DCP2 PF05026.8 ETN97725.1 - 0.07 13.0 0.1 0.23 11.3 0.1 1.9 1 0 0 1 1 1 0 Dcp2, box A domain Closter_coat PF01785.12 ETN97726.1 - 0.071 12.1 0.0 0.08 11.9 0.0 1.0 1 0 0 1 1 1 0 Closterovirus coat protein DUF1410 PF07198.6 ETN97726.1 - 0.15 12.4 1.8 0.17 12.2 1.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1410) WD40 PF00400.27 ETN97728.1 - 1.4e-16 59.6 3.5 2.4e-08 33.5 0.1 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat Mt_ATP-synt_B PF05405.9 ETN97728.1 - 0.04 13.3 0.0 0.056 12.9 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) MKT1_C PF12246.3 ETN97731.1 - 0.053 12.5 0.0 0.073 12.0 0.0 1.2 1 0 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication CRCB PF02537.10 ETN97732.1 - 1.5e-06 28.0 0.3 1.5e-06 28.0 0.2 1.6 2 0 0 2 2 2 1 CrcB-like protein Hid1 PF12722.2 ETN97733.1 - 0.093 10.4 26.2 0.11 10.1 18.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MIP-T3 PF10243.4 ETN97733.1 - 0.16 10.4 56.3 0.21 10.0 39.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Daxx PF03344.10 ETN97733.1 - 0.23 9.9 37.5 0.31 9.4 26.0 1.1 1 0 0 1 1 1 0 Daxx Family TFIIF_alpha PF05793.7 ETN97733.1 - 1 7.6 50.0 1.2 7.3 34.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Atrophin-1 PF03154.10 ETN97733.1 - 3.2 5.7 30.5 7.4 4.5 21.2 1.6 1 1 0 1 1 1 0 Atrophin-1 family PLRV_ORF5 PF01690.12 ETN97733.1 - 7.4 5.5 30.7 9.2 5.2 21.3 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein WD40 PF00400.27 ETN97734.1 - 2.4e-26 90.5 2.3 5.7e-09 35.5 0.3 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN97734.1 - 0.0038 15.4 1.4 1.1 7.3 0.1 2.6 2 1 0 2 2 2 2 Nucleoporin Nup120/160 AAA_13 PF13166.1 ETN97734.1 - 0.023 13.2 17.0 0.027 12.9 11.8 1.1 1 0 0 1 1 1 0 AAA domain Lyase_1 PF00206.15 ETN97734.1 - 0.028 13.6 3.9 0.041 13.0 2.7 1.2 1 0 0 1 1 1 0 Lyase DUF4200 PF13863.1 ETN97734.1 - 0.17 11.8 17.7 0.25 11.2 12.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF2408 PF10303.4 ETN97734.1 - 0.33 11.0 11.4 0.44 10.6 7.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Peptidase_U49 PF10463.4 ETN97734.1 - 0.35 10.6 6.5 0.53 10.0 4.5 1.3 1 0 0 1 1 1 0 Peptidase U49 PNPase PF03726.9 ETN97734.1 - 0.96 9.7 5.4 2.3 8.5 3.7 1.7 1 0 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Asp-B-Hydro_N PF05279.6 ETN97734.1 - 1.7 8.4 10.7 2.1 8.1 7.4 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Costars PF14705.1 ETN97734.1 - 2.8 8.0 5.6 8.9 6.3 1.7 2.8 1 1 1 2 2 2 0 Costars IncA PF04156.9 ETN97734.1 - 4.3 6.8 13.7 6.3 6.3 9.5 1.3 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 ETN97734.1 - 4.3 5.0 10.2 4.8 4.9 7.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HORMA PF02301.13 ETN97734.1 - 5.3 6.4 13.2 7.1 6.0 8.6 1.6 1 1 1 2 2 2 0 HORMA domain Rep_trans PF02486.14 ETN97735.1 - 0.54 9.7 5.3 0.58 9.6 0.2 2.4 1 1 1 2 2 2 0 Replication initiation factor DPPIV_N PF00930.16 ETN97737.1 - 6.4e-05 21.6 0.0 7.2e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region TPR_12 PF13424.1 ETN97738.1 - 4.9e-88 289.1 8.7 3.5e-25 87.7 0.0 3.9 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.1 ETN97738.1 - 7.5e-45 147.2 1.0 3.6e-08 32.6 0.0 5.4 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETN97738.1 - 4.5e-44 147.1 0.0 1.9e-09 37.1 0.0 5.2 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.23 ETN97738.1 - 5.3e-43 142.9 21.8 3.3e-09 35.9 0.5 5.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETN97738.1 - 1.8e-36 123.5 10.0 1.9e-15 56.2 0.2 4.4 3 2 0 4 4 4 4 TPR repeat TPR_2 PF07719.12 ETN97738.1 - 1.6e-33 111.8 12.1 1.7e-06 27.5 0.1 5.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 ETN97738.1 - 2.1e-32 108.4 32.1 2.4e-07 30.0 1.6 5.5 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_17 PF13431.1 ETN97738.1 - 2.6e-24 83.3 0.7 0.0021 18.1 0.0 5.8 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.1 ETN97738.1 - 3.2e-15 56.3 0.0 0.00034 21.2 0.0 4.7 3 1 3 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETN97738.1 - 1.1e-13 50.5 0.0 0.16 12.6 0.0 5.4 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETN97738.1 - 3.5e-12 45.9 2.2 0.004 17.5 0.1 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 ETN97738.1 - 1.6e-11 44.1 9.5 0.00082 19.4 2.0 5.0 1 1 5 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 ETN97738.1 - 3.9e-09 35.8 9.8 0.39 10.8 0.0 6.2 6 0 0 6 6 6 3 PPR repeat MIT PF04212.13 ETN97738.1 - 5.9e-08 32.4 14.4 0.19 11.6 0.1 5.2 5 0 0 5 5 5 3 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 ETN97738.1 - 2.3e-07 30.4 16.2 0.016 14.9 0.2 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat SNAP PF14938.1 ETN97738.1 - 6.1e-07 28.8 5.3 5.1e-05 22.5 1.8 2.7 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_19 PF14559.1 ETN97738.1 - 2.5e-06 27.7 0.1 2.4 8.5 0.0 3.8 3 2 0 3 3 3 2 Tetratricopeptide repeat DUF627 PF04781.7 ETN97738.1 - 6.2e-05 22.5 4.3 2.7 7.6 0.0 4.3 2 2 2 4 4 4 1 Protein of unknown function (DUF627) Pep3_Vps18 PF05131.9 ETN97738.1 - 0.00016 21.1 3.0 11 5.3 0.0 4.9 3 1 1 5 5 5 0 Pep3/Vps18/deep orange family Sel1 PF08238.7 ETN97738.1 - 0.00017 22.1 6.9 4.7 7.9 0.1 5.0 5 0 0 5 5 5 1 Sel1 repeat SHNi-TPR PF10516.4 ETN97738.1 - 0.00028 20.0 0.1 3.1 7.1 0.0 4.0 4 0 0 4 4 4 1 SHNi-TPR DUF2642 PF10842.3 ETN97738.1 - 0.0011 18.3 0.2 11 5.5 0.0 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF2642) DUF357 PF04010.8 ETN97738.1 - 0.0018 17.9 10.9 5.3 6.8 0.4 5.1 1 1 4 5 5 5 0 Protein of unknown function (DUF357) RPN7 PF10602.4 ETN97738.1 - 0.0073 15.7 10.1 4.3 6.6 0.1 4.7 1 1 0 3 3 3 1 26S proteasome subunit RPN7 Ten1_2 PF15490.1 ETN97738.1 - 0.011 15.3 0.1 29 4.2 0.0 3.9 1 1 3 4 4 4 0 Telomere-capping, CST complex subunit DUF3568 PF12092.3 ETN97738.1 - 0.013 15.2 4.1 0.62 9.7 0.4 3.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3568) DUF3775 PF12616.3 ETN97738.1 - 0.047 13.4 0.0 0.96 9.2 0.0 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF3775) DUF386 PF04074.7 ETN97738.1 - 1.7 8.1 9.6 4.1 6.8 3.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF386) DUF3450 PF11932.3 ETN97738.1 - 2.6 7.2 5.2 26 3.9 0.1 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF3450) Tautomerase PF01361.16 ETN97739.1 - 0.32 10.6 0.1 0.32 10.6 0.1 1.8 2 0 0 2 2 2 0 Tautomerase enzyme DUF3288 PF11691.3 ETN97740.1 - 0.076 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3288) PH_BEACH PF14844.1 ETN97740.1 - 0.56 10.0 3.6 0.27 11.0 0.1 2.1 2 1 1 3 3 3 0 PH domain associated with Beige/BEACH LicD PF04991.8 ETN97742.1 - 3.4 7.7 15.1 4 7.4 10.4 1.1 1 0 0 1 1 1 0 LicD family Ycf1 PF05758.7 ETN97743.1 - 0.75 7.4 21.4 0.0086 13.8 9.5 1.6 2 0 0 2 2 2 0 Ycf1 FHIPEP PF00771.15 ETN97743.1 - 9.4 4.4 6.4 10 4.2 3.9 1.4 1 1 0 1 1 1 0 FHIPEP family COG2 PF06148.6 ETN97744.1 - 0.0052 16.6 5.2 0.0067 16.3 3.0 1.5 1 1 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3584 PF12128.3 ETN97744.1 - 0.0079 13.5 6.5 0.0098 13.2 4.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) ArdA PF07275.6 ETN97744.1 - 0.016 15.4 3.4 0.029 14.6 2.4 1.4 1 0 0 1 1 1 0 Antirestriction protein (ArdA) IncA PF04156.9 ETN97744.1 - 0.37 10.3 5.7 0.52 9.8 3.9 1.3 1 0 0 1 1 1 0 IncA protein DUF745 PF05335.8 ETN97744.1 - 0.53 9.7 4.1 1.3 8.4 2.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF745) Lge1 PF11488.3 ETN97744.1 - 0.73 10.0 7.2 5.4 7.2 4.2 2.6 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 Occludin_ELL PF07303.8 ETN97744.1 - 1 10.1 10.7 0.85 10.3 6.3 1.7 2 0 0 2 2 1 0 Occludin homology domain Mur_ligase_M PF08245.7 ETN97744.1 - 1.1 9.2 5.6 0.44 10.5 1.7 1.8 1 1 1 2 2 2 0 Mur ligase middle domain LMBR1 PF04791.11 ETN97744.1 - 1.6 7.2 4.0 1.9 6.9 2.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF739 PF05339.6 ETN97744.1 - 3.6 7.3 6.7 19 5.0 4.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF739) TMPIT PF07851.8 ETN97744.1 - 4.2 6.3 12.0 4 6.4 7.2 1.6 1 1 1 2 2 2 0 TMPIT-like protein DUF2203 PF09969.4 ETN97744.1 - 6 7.1 8.1 1.4e+02 2.6 5.6 2.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) IFT46_B_C PF12317.3 ETN97744.1 - 7.4 5.8 11.5 35 3.6 7.7 2.1 1 1 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal DUF1829 PF08862.5 ETN97744.1 - 8.6 6.7 10.2 1.8 8.8 4.2 2.1 2 1 0 2 2 2 0 Domain of unknown function DUF1829 DnaJ PF00226.26 ETN97745.1 - 2.5e-12 46.3 0.1 7e-12 44.9 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.15 ETN97745.1 - 3e-07 30.0 0.1 8.1e-07 28.6 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.1 ETN97745.1 - 0.00012 21.9 0.4 0.27 11.0 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like domain CENP-B_dimeris PF09026.5 ETN97745.1 - 0.0055 16.9 3.1 0.16 12.2 0.2 2.4 2 0 0 2 2 2 1 Centromere protein B dimerisation domain OAD_gamma PF04277.8 ETN97745.1 - 0.18 12.2 0.8 0.8 10.1 0.2 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain NARP1 PF12569.3 ETN97746.1 - 8.2e-89 298.7 15.0 2.1e-85 287.4 9.7 4.5 2 1 1 3 3 3 1 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 ETN97746.1 - 1.5e-10 40.5 5.8 8.1e-05 22.1 0.0 4.9 6 0 0 6 6 6 2 TPR repeat TPR_12 PF13424.1 ETN97746.1 - 9e-08 31.9 1.1 0.054 13.4 0.0 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETN97746.1 - 3.2e-07 29.7 5.4 0.03 14.2 0.0 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETN97746.1 - 5.8e-06 26.4 1.4 50 4.9 0.0 6.3 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETN97746.1 - 0.00028 21.4 3.9 1.4 9.7 0.1 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETN97746.1 - 0.0013 18.3 2.7 3.4 7.6 0.1 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETN97746.1 - 0.0016 18.1 0.1 0.47 10.3 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETN97746.1 - 0.022 14.3 8.5 0.12 11.9 0.0 5.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETN97746.1 - 0.15 12.4 10.7 4.2 7.7 0.2 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat WD40 PF00400.27 ETN97747.1 - 9.9e-32 107.6 7.6 2.1e-13 49.5 0.0 3.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN97747.1 - 0.0025 16.0 1.2 0.07 11.2 0.4 2.5 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETN97747.1 - 0.0097 14.6 1.8 0.036 12.8 1.3 1.8 1 1 0 1 1 1 1 Nup133 N terminal like BBS2_Mid PF14783.1 ETN97747.1 - 0.055 13.2 0.5 11 5.8 0.0 3.2 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region TPR_11 PF13414.1 ETN97748.1 - 5.5e-23 80.3 6.0 1.4e-11 43.8 0.2 2.6 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETN97748.1 - 5.4e-15 54.2 6.1 6.6e-08 31.8 1.4 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETN97748.1 - 2.2e-13 48.9 9.1 2.6e-06 26.9 0.6 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETN97748.1 - 2.3e-10 40.1 0.3 0.00026 21.3 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETN97748.1 - 3.5e-10 40.2 0.1 0.0012 19.4 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETN97748.1 - 8.6e-06 26.0 0.0 0.029 14.6 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat RPN7 PF10602.4 ETN97748.1 - 2.5e-05 23.7 8.9 0.0002 20.7 2.2 2.4 1 1 0 2 2 2 2 26S proteasome subunit RPN7 TPR_8 PF13181.1 ETN97748.1 - 2.8e-05 23.5 6.3 0.0023 17.6 0.4 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETN97748.1 - 3.2e-05 23.4 0.1 0.059 13.1 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETN97748.1 - 5.8e-05 23.2 2.9 0.049 14.0 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETN97748.1 - 0.00079 19.3 6.1 0.39 10.6 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETN97748.1 - 0.017 14.9 0.0 0.25 11.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 ETN97748.1 - 0.017 15.2 7.9 0.53 10.6 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat GAGA_bind PF06217.7 ETN97748.1 - 1.7 8.5 11.2 0.38 10.6 5.5 1.6 2 0 0 2 2 2 0 GAGA binding protein-like family DHHW PF14286.1 ETN97748.1 - 1.8 7.8 9.6 2.8 7.1 6.6 1.5 1 0 0 1 1 1 0 DHHW protein V_ATPase_I PF01496.14 ETN97748.1 - 3.1 5.5 7.9 4 5.1 5.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HSP70 PF00012.15 ETN97749.1 - 7.9e-47 159.4 0.0 2.8e-46 157.6 0.0 1.7 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 ETN97749.1 - 2e-05 23.3 0.0 7.5e-05 21.4 0.0 2.0 2 1 1 3 3 3 1 MreB/Mbl protein Trp_syntA PF00290.15 ETN97750.1 - 0.056 11.9 0.2 0.17 10.4 0.0 1.8 2 0 0 2 2 2 0 Tryptophan synthase alpha chain Inhibitor_I9 PF05922.11 ETN97753.1 - 0.41 11.2 2.3 6.6 7.3 1.6 2.1 1 1 0 1 1 1 0 Peptidase inhibitor I9 DUF2709 PF10915.3 ETN97754.1 - 0.0016 17.4 0.0 0.002 17.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2709) DUF3035 PF11233.3 ETN97755.1 - 0.016 15.2 0.1 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) OAD_gamma PF04277.8 ETN97756.1 - 0.024 14.9 0.0 0.032 14.5 0.0 1.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF1514 PF07438.6 ETN97756.1 - 0.074 12.9 0.2 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1514) Dapper PF15268.1 ETN97757.1 - 0.0021 16.9 21.3 0.0024 16.7 14.7 1.0 1 0 0 1 1 1 1 Dapper GAGA_bind PF06217.7 ETN97757.1 - 0.0022 18.0 21.4 0.0032 17.4 14.8 1.3 1 0 0 1 1 1 1 GAGA binding protein-like family DUF2201_N PF13203.1 ETN97757.1 - 0.0091 15.2 13.5 0.0099 15.0 9.3 1.1 1 0 0 1 1 1 1 Putative metallopeptidase domain SprA-related PF12118.3 ETN97757.1 - 0.025 13.9 31.0 0.03 13.6 21.5 1.1 1 0 0 1 1 1 0 SprA-related family DUF1510 PF07423.6 ETN97757.1 - 0.036 13.4 38.1 0.047 13.0 26.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Zip PF02535.17 ETN97757.1 - 0.037 13.0 7.4 0.051 12.5 5.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.8 ETN97757.1 - 0.066 11.7 26.6 0.084 11.3 18.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2052 PF09747.4 ETN97757.1 - 0.08 12.8 27.9 0.13 12.1 19.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) U79_P34 PF03064.11 ETN97757.1 - 0.14 11.6 25.6 0.19 11.2 17.7 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF4045 PF13254.1 ETN97757.1 - 0.26 10.5 24.3 0.3 10.3 16.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Ydc2-catalyt PF09159.5 ETN97757.1 - 0.33 10.3 21.8 0.43 10.0 15.1 1.1 1 0 0 1 1 1 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Raftlin PF15250.1 ETN97757.1 - 0.36 9.2 20.8 0.53 8.7 14.4 1.3 1 0 0 1 1 1 0 Raftlin FLO_LFY PF01698.11 ETN97757.1 - 0.59 8.9 23.6 0.96 8.2 16.3 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein Cellulose_synt PF03552.9 ETN97757.1 - 0.63 8.2 10.4 0.8 7.9 7.2 1.2 1 0 0 1 1 1 0 Cellulose synthase Pilt PF15453.1 ETN97757.1 - 0.64 9.6 18.6 0.75 9.4 12.9 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Asp-B-Hydro_N PF05279.6 ETN97757.1 - 0.7 9.6 28.7 0.9 9.3 19.9 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Ycf1 PF05758.7 ETN97757.1 - 0.76 7.4 30.9 0.9 7.1 21.4 1.0 1 0 0 1 1 1 0 Ycf1 CDC27 PF09507.5 ETN97757.1 - 0.87 8.7 39.6 1 8.4 27.5 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 APG6 PF04111.7 ETN97757.1 - 0.94 8.4 26.4 1.1 8.2 18.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Mitofilin PF09731.4 ETN97757.1 - 1 7.8 30.0 1.2 7.6 20.8 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MIP-T3 PF10243.4 ETN97757.1 - 1.2 7.5 53.1 1.5 7.1 36.8 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 MMR1 PF08505.5 ETN97757.1 - 1.2 9.0 21.1 1.6 8.7 14.6 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein UPF0560 PF10577.4 ETN97757.1 - 1.7 6.8 14.9 1.9 6.6 10.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Vfa1 PF08432.5 ETN97757.1 - 2 8.3 43.6 4 7.4 30.2 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nucleo_P87 PF07267.6 ETN97757.1 - 2.2 6.8 21.1 2.6 6.6 14.6 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Sec62 PF03839.11 ETN97757.1 - 2.2 7.6 37.0 3.5 6.9 25.7 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DHHW PF14286.1 ETN97757.1 - 2.4 7.4 18.1 3.2 6.9 12.6 1.2 1 0 0 1 1 1 0 DHHW protein Neur_chan_memb PF02932.11 ETN97757.1 - 2.6 7.8 16.2 3.3 7.5 11.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PA26 PF04636.8 ETN97757.1 - 2.8 6.5 16.9 3.2 6.3 11.7 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PLRV_ORF5 PF01690.12 ETN97757.1 - 2.8 6.9 22.2 3.3 6.7 15.4 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Parvo_coat PF00740.13 ETN97757.1 - 3.1 6.6 17.4 3.6 6.4 12.0 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Apt1 PF10351.4 ETN97757.1 - 3.3 6.4 21.1 3.9 6.2 14.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SID-1_RNA_chan PF13965.1 ETN97757.1 - 3.7 5.5 10.5 4.3 5.3 7.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 HSP70 PF00012.15 ETN97757.1 - 4 5.2 23.7 4.5 5.0 16.4 1.0 1 0 0 1 1 1 0 Hsp70 protein GPCR_chapero_1 PF11904.3 ETN97757.1 - 4.7 6.2 23.4 5.9 5.9 16.2 1.1 1 0 0 1 1 1 0 GPCR-chaperone SOBP PF15279.1 ETN97757.1 - 4.8 7.4 16.1 6.4 7.0 11.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Caldesmon PF02029.10 ETN97757.1 - 5.5 5.2 39.4 7.1 4.9 27.3 1.1 1 0 0 1 1 1 0 Caldesmon CDC45 PF02724.9 ETN97757.1 - 6.6 4.6 30.0 8.4 4.2 20.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.10 ETN97757.1 - 7.1 5.1 23.0 8.8 4.8 15.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.2 ETN97757.1 - 7.6 4.0 24.1 9 3.8 16.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Peptidase_C37 PF05416.7 ETN97757.1 - 8.1 4.6 15.6 11 4.1 10.8 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase CAF-1_p150 PF11600.3 ETN97757.1 - 8.4 5.6 64.5 12 5.2 44.7 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal A_deaminase PF00962.17 ETN97758.1 - 7.7e-07 28.3 0.0 1.5e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 Adenosine/AMP deaminase WGG PF10273.4 ETN97758.1 - 0.23 11.5 2.2 0.32 11.1 0.9 1.8 2 1 0 2 2 2 0 Pre-rRNA-processing protein TSR2 Pox_A3L PF05288.6 ETN97760.1 - 0.043 13.5 2.4 3.5 7.4 0.2 2.2 1 1 1 2 2 2 0 Poxvirus A3L Protein DWNN PF08783.6 ETN97760.1 - 0.29 11.1 3.5 2.5 8.1 0.2 2.1 1 1 1 2 2 2 0 DWNN domain DUF1829 PF08862.5 ETN97760.1 - 1.6 9.0 7.2 8.6 6.7 1.0 2.8 1 1 1 2 2 2 0 Domain of unknown function DUF1829 DUF1410 PF07198.6 ETN97760.1 - 7.8 6.8 11.6 0.32 11.3 1.5 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1410) Sulfotransfer_3 PF13469.1 ETN97761.1 - 0.03 15.2 0.0 0.046 14.6 0.0 1.3 1 0 0 1 1 1 0 Sulfotransferase family DUF2413 PF10310.4 ETN97761.1 - 0.053 12.3 5.8 0.079 11.7 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Equine_IAV_S2 PF06502.6 ETN97761.1 - 0.074 12.9 1.4 0.18 11.6 1.0 1.7 1 0 0 1 1 1 0 Equine infectious anaemia virus S2 protein Pox_G5 PF04599.7 ETN97761.1 - 0.15 10.7 8.6 0.23 10.1 5.9 1.2 1 0 0 1 1 1 0 Poxvirus G5 protein Agouti PF05039.7 ETN97761.1 - 4.3 7.7 7.7 0.66 10.3 1.1 2.6 3 0 0 3 3 3 0 Agouti protein Inhibitor_I71 PF12628.2 ETN97761.1 - 7 6.2 11.2 13 5.3 7.7 1.5 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor CENP-T PF15511.1 ETN97762.1 - 0.04 13.1 17.2 0.043 13.0 11.9 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Daxx PF03344.10 ETN97762.1 - 0.14 10.5 27.9 0.16 10.4 19.4 1.0 1 0 0 1 1 1 0 Daxx Family DUF999 PF06198.6 ETN97762.1 - 0.57 9.9 7.6 0.91 9.2 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF999) Sporozoite_P67 PF05642.6 ETN97762.1 - 0.6 7.9 14.8 0.76 7.5 10.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen WD40 PF00400.27 ETN97763.1 - 7.5e-12 44.6 0.1 1.9e-10 40.1 0.0 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETN97763.1 - 0.051 11.7 0.0 0.051 11.7 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Alpha-L-AF_C PF06964.7 ETN97763.1 - 0.095 12.4 0.0 0.12 12.1 0.0 1.0 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase C-terminus HAD PF12710.2 ETN97763.1 - 0.13 12.4 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase RNase_H PF00075.19 ETN97764.1 - 5.2e-09 36.5 0.0 7.6e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 RNase H RPAP1_N PF08621.5 ETN97764.1 - 0.0095 15.5 0.2 0.023 14.2 0.0 1.7 2 0 0 2 2 2 1 RPAP1-like, N-terminal RVT_3 PF13456.1 ETN97764.1 - 0.017 14.8 0.0 0.029 14.1 0.0 1.5 1 1 0 1 1 1 0 Reverse transcriptase-like AfsA PF03756.8 ETN97764.1 - 0.11 12.2 0.0 0.21 11.2 0.0 1.5 1 1 0 1 1 1 0 A-factor biosynthesis hotdog domain WD40 PF00400.27 ETN97765.1 - 4.8e-17 61.1 4.1 1.2e-11 44.0 0.0 3.3 3 1 0 3 3 3 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 ETN97765.1 - 0.0079 15.9 0.3 0.03 14.0 0.1 2.0 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 ETN97765.1 - 0.078 11.1 0.0 0.27 9.3 0.0 1.6 1 1 1 2 2 2 0 Nucleoporin Nup120/160 UpxZ PF06603.6 ETN97765.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.4 1 1 0 1 1 1 0 UpxZ family of transcription anti-terminator antagonists Pex24p PF06398.6 ETN97766.1 - 0.13 11.0 3.0 0.14 10.9 2.1 1.0 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin NACHT PF05729.7 ETN97768.1 - 1.3e-08 34.6 0.0 2.1e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETN97768.1 - 1.7e-06 28.3 0.5 6.1e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETN97768.1 - 3.9e-05 23.8 0.0 6.6e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain UPF0079 PF02367.12 ETN97768.1 - 5.4e-05 22.8 0.1 0.00012 21.6 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 ETN97768.1 - 0.00067 20.4 0.3 0.0012 19.6 0.0 1.7 2 1 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 ETN97768.1 - 0.003 17.6 0.2 0.0095 16.1 0.1 2.0 1 1 0 1 1 1 1 RNA helicase ABC_tran PF00005.22 ETN97768.1 - 0.0031 17.7 0.1 0.0046 17.2 0.1 1.3 1 1 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.7 ETN97768.1 - 0.0039 16.3 0.1 0.0098 15.0 0.0 1.6 1 1 0 1 1 1 1 Zeta toxin ATP_bind_2 PF03668.10 ETN97768.1 - 0.0066 15.5 0.0 0.0082 15.2 0.0 1.2 1 0 0 1 1 1 1 P-loop ATPase protein family DUF258 PF03193.11 ETN97768.1 - 0.0069 15.5 0.1 0.01 15.0 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 PRK PF00485.13 ETN97768.1 - 0.01 15.4 0.0 0.014 14.9 0.0 1.3 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 ETN97768.1 - 0.011 15.6 0.0 0.016 15.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 ETN97768.1 - 0.015 14.9 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 ETN97768.1 - 0.015 15.2 2.8 0.032 14.1 1.9 1.6 1 1 0 1 1 1 0 AAA domain Torsin PF06309.6 ETN97768.1 - 0.018 14.9 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Torsin Sigma54_activat PF00158.21 ETN97768.1 - 0.027 13.9 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.9 ETN97768.1 - 0.049 13.3 0.0 0.085 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.9 ETN97768.1 - 0.052 12.5 0.3 0.069 12.1 0.2 1.4 1 1 0 1 1 1 0 KAP family P-loop domain KaiC PF06745.8 ETN97768.1 - 0.061 12.4 0.4 0.31 10.1 0.0 2.0 1 1 1 2 2 2 0 KaiC PduV-EutP PF10662.4 ETN97768.1 - 0.071 12.6 0.0 0.14 11.6 0.0 1.5 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.12 ETN97768.1 - 0.092 12.1 0.0 0.095 12.1 0.0 1.3 1 1 0 1 1 1 0 IstB-like ATP binding protein CPT PF07931.7 ETN97768.1 - 0.11 12.0 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.1 ETN97768.1 - 0.14 12.1 0.1 0.32 10.9 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.15 ETN97768.1 - 0.17 10.5 2.8 0.28 9.7 2.0 1.5 1 1 0 1 1 1 0 G-protein alpha subunit FadA PF09403.5 ETN97768.1 - 1.4 8.9 5.6 3 7.8 0.1 2.2 1 1 1 2 2 2 0 Adhesion protein FadA RNA_pol_Rpb5_C PF01191.14 ETN97769.1 - 0.12 11.9 2.4 0.39 10.3 0.2 2.4 2 1 1 3 3 3 0 RNA polymerase Rpb5, C-terminal domain Folate_carrier PF01770.13 ETN97770.1 - 3.4 6.0 6.9 3.8 5.9 4.8 1.0 1 0 0 1 1 1 0 Reduced folate carrier Rad51 PF08423.6 ETN97771.1 - 0.00082 18.3 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 Rad51 ABC_tran PF00005.22 ETN97771.1 - 0.0015 18.8 0.8 0.0047 17.2 0.4 1.9 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 ETN97771.1 - 0.0032 16.9 0.0 0.0076 15.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 ETN97771.1 - 0.009 15.4 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain NARP1 PF12569.3 ETN97772.1 - 4.1e-28 98.4 6.3 1.6e-25 89.8 6.7 2.3 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 EST1 PF10374.4 ETN97772.1 - 0.0007 19.5 1.5 0.0007 19.5 1.1 2.4 3 1 0 3 3 3 1 Telomerase activating protein Est1 DUF4181 PF13789.1 ETN97775.1 - 0.2 11.5 1.7 0.24 11.3 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) O-ag_pol_Wzy PF14296.1 ETN97776.1 - 0.013 14.0 0.7 0.017 13.7 0.5 1.1 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy SAM_1 PF00536.25 ETN97779.1 - 0.0049 17.0 0.0 0.011 15.9 0.0 1.6 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) RelA_SpoT PF04607.12 ETN97781.1 - 0.0035 17.3 0.7 0.021 14.8 0.1 2.3 2 0 0 2 2 2 1 Region found in RelA / SpoT proteins Papilloma_E5 PF03025.9 ETN97782.1 - 0.57 10.1 4.6 1 9.3 3.2 1.3 1 0 0 1 1 1 0 Papillomavirus E5 DUF3546 PF12066.3 ETN97782.1 - 2 8.4 5.1 5.8 6.9 2.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3546) Kelch_4 PF13418.1 ETN97783.1 - 8.9e-07 28.5 0.2 0.0018 18.0 0.1 2.5 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETN97783.1 - 2e-06 27.3 0.2 0.0061 16.2 0.1 2.6 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.20 ETN97783.1 - 2.7e-06 26.8 1.1 9.7e-06 25.0 0.5 2.0 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETN97783.1 - 4.3e-06 26.6 1.0 0.0018 18.4 0.3 2.5 1 1 1 2 2 2 2 Kelch motif Kelch_3 PF13415.1 ETN97783.1 - 0.00066 19.7 0.1 0.003 17.6 0.0 2.1 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETN97783.1 - 0.00081 19.2 0.9 0.0029 17.5 0.7 1.9 2 0 0 2 2 2 1 Kelch motif GEMIN8 PF15348.1 ETN97786.1 - 0.074 13.0 0.3 0.089 12.8 0.2 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DUF3876 PF12992.2 ETN97786.1 - 0.094 12.6 0.4 0.44 10.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3876) Lipocalin_4 PF13648.1 ETN97786.1 - 0.13 12.8 4.8 0.23 12.1 1.0 2.2 1 1 1 2 2 2 0 Lipocalin-like domain Mastoparan_2 PF08251.6 ETN97787.1 - 0.72 10.0 3.5 3 8.1 1.2 2.8 2 0 0 2 2 2 0 Mastoparan peptide UCH PF00443.24 ETN97788.1 - 0.0016 17.6 11.8 0.062 12.3 8.2 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2746 PF10874.3 ETN97788.1 - 0.019 15.1 0.1 0.077 13.1 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2746) Fer4_7 PF12838.2 ETN97788.1 - 0.05 13.9 1.3 0.17 12.2 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain UPF0547 PF10571.4 ETN97788.1 - 0.088 12.5 3.8 10 5.9 1.3 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 UCH PF00443.24 ETN97789.1 - 4.6e-17 62.0 25.2 2.5e-15 56.3 17.5 3.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF4231 PF14015.1 ETN97789.1 - 0.1 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) PNPase PF03726.9 ETN97789.1 - 0.15 12.3 2.0 1.1 9.6 0.1 3.1 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain WD40 PF00400.27 ETN97790.1 - 2.7e-42 141.1 16.6 2.7e-12 46.0 1.2 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETN97790.1 - 7.7e-06 24.3 0.1 0.28 9.2 0.1 3.5 3 1 1 4 4 4 3 Nucleoporin Nup120/160 DUF148 PF02520.12 ETN97792.1 - 0.017 14.9 6.0 0.017 14.9 4.2 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF148 TGT PF01702.13 ETN97792.1 - 0.047 12.9 0.6 0.059 12.6 0.4 1.2 1 0 0 1 1 1 0 Queuine tRNA-ribosyltransferase Aminotran_5 PF00266.14 ETN97792.1 - 0.049 12.3 1.4 0.83 8.3 0.0 2.0 1 1 1 2 2 2 0 Aminotransferase class-V NLE PF08154.7 ETN97792.1 - 0.092 12.7 1.2 0.7 9.9 0.1 2.5 1 1 0 2 2 2 0 NLE (NUC135) domain Casein PF00363.13 ETN97792.1 - 0.11 13.1 2.0 0.25 12.0 1.4 1.6 1 0 0 1 1 1 0 Casein ASL_C PF08328.6 ETN97792.1 - 0.17 11.7 1.9 0.43 10.4 1.3 1.6 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal OSCP PF00213.13 ETN97792.1 - 0.22 11.3 6.0 0.14 12.0 1.5 1.9 1 1 1 2 2 2 0 ATP synthase delta (OSCP) subunit DUF725 PF05267.7 ETN97792.1 - 0.33 10.8 3.1 1.1 9.1 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF725) DUF948 PF06103.6 ETN97792.1 - 0.34 10.8 10.1 0.65 9.8 3.4 3.0 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) TMPIT PF07851.8 ETN97792.1 - 0.47 9.4 9.1 0.58 9.1 6.0 1.4 1 1 0 1 1 1 0 TMPIT-like protein Cortex-I_coil PF09304.5 ETN97792.1 - 0.61 10.1 9.1 0.38 10.8 3.9 2.1 2 0 0 2 2 2 0 Cortexillin I, coiled coil COG5 PF10392.4 ETN97792.1 - 1.4 8.8 8.0 0.31 11.0 2.6 2.0 2 1 0 2 2 2 0 Golgi transport complex subunit 5 AF0941-like PF14591.1 ETN97792.1 - 3.4 7.7 11.0 4.6 7.3 4.9 2.2 1 1 1 2 2 2 0 AF0941-like DUF2262 PF10020.4 ETN97792.1 - 3.8 7.6 12.4 3.3 7.8 1.0 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2262) CofC PF01983.11 ETN97793.1 - 0.062 12.2 0.5 0.071 12.0 0.3 1.1 1 0 0 1 1 1 0 Guanylyl transferase CofC like Peroxidase_2 PF01328.12 ETN97794.1 - 0.097 11.3 3.2 0.11 11.1 2.2 1.1 1 0 0 1 1 1 0 Peroxidase, family 2 ApoO PF09769.4 ETN97794.1 - 0.16 11.6 4.9 0.28 10.8 3.4 1.6 1 1 0 1 1 1 0 Apolipoprotein O Atg14 PF10186.4 ETN97794.1 - 1 8.2 13.3 1.3 7.8 9.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_23 PF13476.1 ETN97794.1 - 1.3 9.2 24.8 2.2 8.5 17.2 1.4 1 0 0 1 1 1 0 AAA domain CRAL_TRIO_N PF03765.10 ETN97794.1 - 2.7 8.2 6.5 12 6.1 4.5 2.2 1 1 0 1 1 1 0 CRAL/TRIO, N-terminal domain AAA_21 PF13304.1 ETN97794.1 - 4.1 7.2 16.3 5.2 6.9 11.3 1.1 1 0 0 1 1 1 0 AAA domain DUF2422 PF10337.4 ETN97794.1 - 7.9 5.1 9.5 0.37 9.5 2.9 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) DUF3395 PF11875.3 ETN97794.1 - 9.1 5.9 17.4 0.82 9.2 4.6 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF3395) Ins_P5_2-kin PF06090.7 ETN97796.1 - 0.095 11.7 0.3 0.095 11.7 0.2 1.1 1 0 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase DsrD PF08679.6 ETN97796.1 - 0.22 11.5 2.7 0.87 9.6 0.0 2.4 2 1 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) ERAP1_C PF11838.3 ETN97799.1 - 4.5e-14 52.4 0.5 2.2e-12 46.8 0.4 2.2 1 1 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.15 ETN97799.1 - 2.6e-07 30.1 0.0 5.2e-07 29.0 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 ETN97799.1 - 0.019 14.9 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase MA superfamily YccJ PF13993.1 ETN97799.1 - 0.054 13.5 0.2 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 YccJ-like protein Vfa1 PF08432.5 ETN97800.1 - 9.6 6.1 25.6 0.026 14.5 7.4 3.1 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 TPR_12 PF13424.1 ETN97801.1 - 2.1e-89 293.5 29.5 2.1e-25 88.4 0.3 3.8 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETN97801.1 - 2.7e-33 112.9 0.0 4.2e-07 29.6 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETN97801.1 - 9.7e-31 104.1 30.4 7.7e-09 34.7 0.5 6.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETN97801.1 - 5.8e-29 97.5 6.2 2.5e-06 26.8 0.0 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETN97801.1 - 1.6e-27 93.1 18.5 7.8e-07 28.5 0.1 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETN97801.1 - 3.3e-27 93.9 21.0 9.5e-15 54.0 2.1 4.5 2 1 1 4 4 4 3 TPR repeat TPR_8 PF13181.1 ETN97801.1 - 1.5e-20 71.3 28.3 3.1e-07 29.6 0.8 5.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETN97801.1 - 6e-13 49.0 1.0 3.4e-05 24.3 0.0 4.2 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETN97801.1 - 8.5e-12 44.2 9.9 0.13 12.5 0.0 6.2 6 1 0 6 6 5 4 Tetratricopeptide repeat TPR_6 PF13174.1 ETN97801.1 - 5.4e-11 42.2 4.4 0.27 11.8 0.0 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_3 PF07720.7 ETN97801.1 - 6e-11 41.8 21.2 0.0017 18.0 0.5 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETN97801.1 - 9.2e-09 35.1 0.0 2.8 8.8 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 ETN97801.1 - 6.7e-08 32.5 18.5 0.00011 22.3 1.1 4.3 2 1 3 5 5 4 3 Anaphase-promoting complex, cyclosome, subunit 3 Sel1 PF08238.7 ETN97801.1 - 4.3e-05 23.9 13.8 0.12 13.0 0.1 4.6 4 0 0 4 4 4 1 Sel1 repeat SHNi-TPR PF10516.4 ETN97801.1 - 0.00074 18.7 0.1 3.5 6.9 0.0 3.9 4 0 0 4 4 4 1 SHNi-TPR TPR_19 PF14559.1 ETN97801.1 - 0.0011 19.2 2.8 0.99 9.7 0.1 4.1 3 2 2 5 5 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETN97801.1 - 0.0015 18.3 20.8 0.14 12.0 0.7 4.6 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat PPR PF01535.15 ETN97801.1 - 0.0019 18.0 9.9 1.2 9.2 0.0 5.7 6 0 0 6 6 6 1 PPR repeat TPR_9 PF13371.1 ETN97801.1 - 0.011 15.6 0.0 1.1 9.1 0.0 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF357 PF04010.8 ETN97801.1 - 0.056 13.1 15.6 4.1 7.1 0.2 4.4 1 1 3 4 4 4 0 Protein of unknown function (DUF357) ATP-synt_E_2 PF08112.6 ETN97801.1 - 0.066 13.2 5.3 14 5.8 0.1 4.1 3 0 0 3 3 3 0 ATP synthase epsilon subunit ATP-synt_F PF01990.12 ETN97801.1 - 0.12 12.8 0.1 0.29 11.5 0.1 1.6 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit TPR_5 PF12688.2 ETN97801.1 - 0.18 11.8 0.1 4.5 7.3 0.0 2.8 1 1 1 2 2 2 0 Tetratrico peptide repeat Mob_Pre PF01076.14 ETN97801.1 - 0.28 10.7 11.0 0.053 13.1 1.0 3.4 2 1 1 3 3 3 0 Plasmid recombination enzyme MIT PF04212.13 ETN97801.1 - 0.73 9.7 18.7 1.6 8.6 0.6 4.1 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain DUF627 PF04781.7 ETN97801.1 - 1.6 8.4 11.5 18 4.9 0.1 4.4 4 1 1 5 5 5 0 Protein of unknown function (DUF627) RLAN PF14401.1 ETN97801.1 - 8.1 5.9 10.1 8.8 5.8 0.2 3.5 3 0 0 3 3 3 0 RimK-like ATPgrasp N-terminal domain DUF386 PF04074.7 ETN97801.1 - 9 5.7 12.9 0.081 12.4 2.1 2.3 2 1 1 3 3 2 0 Domain of unknown function (DUF386) TPR_12 PF13424.1 ETN97802.1 - 2.9e-57 190.5 14.0 2e-25 88.5 0.6 2.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETN97802.1 - 2e-31 107.4 21.9 3.7e-15 55.3 2.0 3.4 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETN97802.1 - 3.1e-26 89.8 20.0 4.6e-10 38.6 1.4 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETN97802.1 - 4.7e-26 89.9 0.0 1e-07 31.6 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETN97802.1 - 8.6e-24 81.4 2.0 1.2e-07 30.9 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETN97802.1 - 7.5e-22 75.4 12.3 1.1e-07 31.1 0.5 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETN97802.1 - 2.3e-17 61.3 19.8 3.7e-08 32.5 2.5 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETN97802.1 - 1.5e-13 49.7 3.1 9.8e-05 22.2 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETN97802.1 - 3.4e-09 36.5 1.3 0.004 17.5 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETN97802.1 - 7.4e-09 36.0 0.1 2.8e-06 27.8 0.1 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat PPR PF01535.15 ETN97802.1 - 9.4e-07 28.4 6.2 0.08 12.9 0.1 4.9 5 0 0 5 5 5 2 PPR repeat SNAP PF14938.1 ETN97802.1 - 1.5e-06 27.5 8.5 0.00036 19.7 2.1 2.2 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_14 PF13428.1 ETN97802.1 - 3.1e-06 27.3 0.0 0.56 10.9 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_3 PF07720.7 ETN97802.1 - 1.2e-05 24.9 12.1 0.018 14.7 0.2 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat Sel1 PF08238.7 ETN97802.1 - 2.1e-05 24.9 5.7 0.24 12.0 0.1 3.6 3 0 0 3 3 3 2 Sel1 repeat ATP-synt_E_2 PF08112.6 ETN97802.1 - 0.00022 21.2 6.2 0.34 10.9 0.1 3.8 3 0 0 3 3 3 2 ATP synthase epsilon subunit Apc3 PF12895.2 ETN97802.1 - 0.00055 20.0 12.4 0.0043 17.1 3.4 3.7 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETN97802.1 - 0.00064 20.0 1.8 0.17 12.2 0.1 3.5 2 1 2 4 4 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETN97802.1 - 0.036 13.9 7.5 0.071 13.0 0.9 2.8 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 ETN97802.1 - 0.041 13.7 8.7 1.9 8.4 0.4 3.4 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain RPN7 PF10602.4 ETN97802.1 - 0.062 12.6 9.9 1.8 7.9 0.1 3.8 1 1 2 4 4 4 0 26S proteasome subunit RPN7 Mob_Pre PF01076.14 ETN97802.1 - 0.069 12.7 0.4 0.069 12.7 0.3 3.0 2 1 1 3 3 3 0 Plasmid recombination enzyme Ribosomal_S7 PF00177.16 ETN97802.1 - 0.1 12.2 2.3 36 3.9 0.0 3.7 4 0 0 4 4 4 0 Ribosomal protein S7p/S5e SPO22 PF08631.5 ETN97802.1 - 0.34 9.9 4.0 28 3.6 0.1 3.2 2 1 1 3 3 3 0 Meiosis protein SPO22/ZIP4 like DUF357 PF04010.8 ETN97802.1 - 0.43 10.3 7.2 4.8 6.9 0.1 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF357) Prefoldin PF02996.12 ETN97802.1 - 1.2 8.8 5.4 2.7 7.6 0.1 3.1 2 1 1 3 3 3 0 Prefoldin subunit Ubiq-assoc PF09145.5 ETN97802.1 - 3.2 7.6 10.6 8.7 6.3 0.2 4.3 2 2 3 5 5 5 0 Ubiquitin-associated PUB PF09409.5 ETN97804.1 - 0.00075 19.2 1.2 0.00075 19.2 0.9 2.6 2 1 0 2 2 2 1 PUB domain CW_binding_1 PF01473.15 ETN97804.1 - 0.09 12.9 5.0 0.22 11.7 3.5 1.7 1 0 0 1 1 1 0 Putative cell wall binding repeat Dynamin_N PF00350.18 ETN97805.1 - 0.0025 17.6 0.1 0.0025 17.6 0.1 2.9 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 ETN97805.1 - 0.04 13.8 0.8 0.12 12.3 0.5 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase CDC45 PF02724.9 ETN97806.1 - 1.1 7.1 10.7 1.2 7.0 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein HSP90 PF00183.13 ETN97806.1 - 1.6 7.0 12.6 2.1 6.6 8.7 1.2 1 0 0 1 1 1 0 Hsp90 protein Herpes_LMP1 PF05297.6 ETN97806.1 - 7.5 5.3 10.3 9.6 5.0 7.2 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) XPG_I_2 PF12813.2 ETN97808.1 - 0.082 12.3 0.0 0.087 12.2 0.0 1.1 1 0 0 1 1 1 0 XPG domain containing SH3_4 PF06347.8 ETN97809.1 - 0.077 12.5 0.1 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain RVT_1 PF00078.22 ETN97810.1 - 0.011 15.1 1.2 0.015 14.6 0.8 1.5 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Sigma_reg_C PF13791.1 ETN97810.1 - 0.012 15.6 1.5 0.016 15.2 1.0 1.1 1 0 0 1 1 1 0 Sigma factor regulator C-terminal Herpes_TK_C PF08465.5 ETN97810.1 - 0.034 13.6 0.4 0.089 12.3 0.3 1.7 1 0 0 1 1 1 0 Thymidine kinase from Herpesvirus C-terminal Amnionless PF14828.1 ETN97810.1 - 0.049 12.1 0.3 0.063 11.7 0.2 1.1 1 0 0 1 1 1 0 Amnionless DUF2179 PF10035.4 ETN97812.1 - 0.052 13.1 0.1 3.4 7.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2179) DUF2207 PF09972.4 ETN97812.1 - 0.064 11.8 0.2 0.063 11.8 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FAD_binding_4 PF01565.18 ETN97813.1 - 0.0018 17.7 0.0 0.032 13.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Copine PF07002.11 ETN97814.1 - 5.1e-27 94.4 0.6 8.7e-27 93.6 0.4 1.4 1 0 0 1 1 1 1 Copine Adaptin_binding PF10199.4 ETN97815.1 - 0.052 13.8 0.3 0.087 13.1 0.2 1.3 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 RasGEF_N PF00618.15 ETN97816.1 - 0.25 11.4 1.9 0.35 11.0 1.3 1.6 1 1 0 1 1 1 0 RasGEF N-terminal motif Glyco_hydro_2_C PF02836.12 ETN97818.1 - 6.4e-09 35.1 0.4 1.3e-08 34.1 0.3 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF1759 PF03564.10 ETN97820.1 - 2.4 7.9 7.4 0.16 11.7 0.2 2.3 2 1 0 3 3 3 0 Protein of unknown function (DUF1759) Gln-synt_C PF00120.19 ETN97822.1 - 0.00058 19.0 0.0 0.00075 18.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain HEAT PF02985.17 ETN97823.1 - 0.00021 21.1 0.0 0.77 9.9 0.0 2.8 2 1 1 3 3 3 2 HEAT repeat HEAT_2 PF13646.1 ETN97823.1 - 0.00033 20.8 0.0 0.00085 19.5 0.0 1.7 1 1 0 1 1 1 1 HEAT repeats NLE PF08154.7 ETN97823.1 - 0.00074 19.4 0.1 0.013 15.5 0.0 2.1 1 1 1 2 2 2 2 NLE (NUC135) domain Vac14_Fab1_bd PF12755.2 ETN97823.1 - 0.008 16.5 0.1 0.036 14.4 0.0 1.8 1 1 1 2 2 2 1 Vacuolar 14 Fab1-binding region DUF3837 PF12939.2 ETN97823.1 - 0.028 14.4 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3837) XkdW PF09636.5 ETN97823.1 - 0.1 12.4 0.1 0.39 10.6 0.0 1.9 1 1 1 2 2 2 0 XkdW protein Cast PF10174.4 ETN97824.1 - 0.0094 14.0 5.7 0.01 13.9 3.9 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Baculo_PEP_C PF04513.7 ETN97824.1 - 0.01 15.6 6.5 0.015 15.0 4.5 1.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ax_dynein_light PF10211.4 ETN97824.1 - 0.016 15.0 5.0 0.017 14.9 3.5 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain WEMBL PF05701.6 ETN97824.1 - 0.026 12.9 3.9 0.03 12.8 2.7 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light NPV_P10 PF05531.7 ETN97824.1 - 0.06 13.6 8.5 1.5 9.1 5.9 2.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein EMP24_GP25L PF01105.19 ETN97824.1 - 0.066 12.9 3.9 0.094 12.4 2.7 1.4 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF342 PF03961.8 ETN97824.1 - 0.069 11.5 4.5 0.077 11.4 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF724 PF05266.9 ETN97824.1 - 0.086 12.4 5.3 0.096 12.2 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) AAA_23 PF13476.1 ETN97824.1 - 0.097 12.9 5.8 0.11 12.7 4.0 1.1 1 0 0 1 1 1 0 AAA domain CK2S PF15011.1 ETN97824.1 - 0.1 12.4 2.2 3.5 7.3 0.6 2.3 1 1 1 2 2 2 0 Casein Kinase 2 substrate Uds1 PF15456.1 ETN97824.1 - 0.17 11.9 2.6 0.49 10.3 1.8 1.7 1 1 0 1 1 1 0 Up-regulated During Septation Viral_P18 PF04521.8 ETN97824.1 - 0.21 11.0 2.1 0.6 9.5 1.4 1.9 1 1 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein RSS_P20 PF11757.3 ETN97824.1 - 0.28 11.3 2.2 1.7 8.7 0.5 2.1 1 1 1 2 2 2 0 Suppressor of RNA silencing P21-like IncA PF04156.9 ETN97824.1 - 0.29 10.6 3.2 0.34 10.4 2.2 1.2 1 0 0 1 1 1 0 IncA protein FliD_N PF02465.13 ETN97824.1 - 0.31 11.4 2.5 0.85 10.0 1.7 1.8 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus LOH1CR12 PF10158.4 ETN97824.1 - 0.33 10.7 3.5 0.52 10.1 2.4 1.4 1 1 0 1 1 1 0 Tumour suppressor protein FlaC_arch PF05377.6 ETN97824.1 - 0.38 10.6 9.5 13 5.7 3.6 3.3 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Occludin_ELL PF07303.8 ETN97824.1 - 0.79 10.4 4.4 1.1 10.0 3.1 1.3 1 1 0 1 1 1 0 Occludin homology domain DUF16 PF01519.11 ETN97824.1 - 1.1 9.5 7.5 1.6 8.9 5.2 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF1664 PF07889.7 ETN97824.1 - 1.2 8.9 6.0 1.8 8.3 4.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) RTX_C PF08339.5 ETN97824.1 - 1.5 8.4 7.1 3 7.5 4.4 1.8 1 1 1 2 2 2 0 RTX C-terminal domain Fzo_mitofusin PF04799.8 ETN97824.1 - 1.6 8.0 5.9 2.1 7.6 3.5 1.5 1 1 0 1 1 1 0 fzo-like conserved region Syntaxin PF00804.20 ETN97824.1 - 1.8 8.7 9.4 8.3 6.6 3.0 2.6 2 1 0 2 2 2 0 Syntaxin DivIC PF04977.10 ETN97824.1 - 3.8 7.0 10.2 1 8.8 4.0 2.0 1 1 1 2 2 2 0 Septum formation initiator zf-ZPR1 PF03367.8 ETN97825.1 - 0.35 10.0 5.1 0.3 10.2 0.2 2.0 1 1 1 2 2 2 0 ZPR1 zinc-finger domain WD40 PF00400.27 ETN97826.1 - 2.7e-17 61.9 0.6 1.7e-05 24.5 0.0 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN97826.1 - 0.14 10.2 0.5 4.7 5.2 0.0 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 G_glu_transpept PF01019.16 ETN97827.1 - 6.6e-58 196.4 0.0 9e-58 196.0 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase TACC PF05010.9 ETN97828.1 - 0.00095 18.9 0.0 0.0017 18.1 0.0 1.5 1 1 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) Sec66 PF09802.4 ETN97828.1 - 0.16 11.3 3.2 0.073 12.4 0.4 1.9 2 0 0 2 2 2 0 Preprotein translocase subunit Sec66 DUF677 PF05055.7 ETN97828.1 - 0.17 10.5 5.8 1 7.9 3.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF677) Ribosomal_S13 PF00416.17 ETN97828.1 - 0.19 12.2 0.1 0.19 12.2 0.1 2.5 2 1 0 2 2 2 0 Ribosomal protein S13/S18 DUF4446 PF14584.1 ETN97828.1 - 0.22 11.3 3.1 0.19 11.5 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Syntaxin_2 PF14523.1 ETN97828.1 - 0.61 10.1 8.3 0.37 10.8 3.6 2.2 2 0 0 2 2 2 0 Syntaxin-like protein Med4 PF10018.4 ETN97828.1 - 0.64 9.3 7.6 0.034 13.5 1.3 1.8 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 ATP-synt_B PF00430.13 ETN97828.1 - 0.65 9.8 8.2 0.085 12.6 2.8 1.6 2 0 0 2 2 1 0 ATP synthase B/B' CF(0) Seryl_tRNA_N PF02403.17 ETN97828.1 - 0.94 9.5 10.9 0.24 11.4 4.9 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Pyrophosphatase PF00719.14 ETN97828.1 - 1 8.7 5.0 1.9 7.8 0.1 2.4 1 1 1 2 2 2 0 Inorganic pyrophosphatase Med21 PF11221.3 ETN97828.1 - 1.1 9.2 7.1 0.64 9.9 3.2 1.9 2 0 0 2 2 2 0 Subunit 21 of Mediator complex DUF848 PF05852.6 ETN97828.1 - 1.8 8.3 7.2 3.9 7.3 4.2 2.0 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Uds1 PF15456.1 ETN97828.1 - 2.4 8.1 6.1 0.82 9.6 2.0 1.9 2 1 0 2 2 2 0 Up-regulated During Septation DUF603 PF04645.7 ETN97828.1 - 2.6 7.9 8.5 0.98 9.3 4.1 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF603 DUF1664 PF07889.7 ETN97828.1 - 3.5 7.4 6.7 7.1 6.4 4.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.6 ETN97828.1 - 3.6 7.4 9.7 2.6 7.9 4.1 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF904 PF06005.7 ETN97828.1 - 4.3 7.7 13.6 0.6 10.4 6.5 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF904) Ank_2 PF12796.2 ETN97829.1 - 4.2e-11 43.0 0.2 3.2e-10 40.2 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETN97829.1 - 6.1e-08 32.0 0.2 1.7e-05 24.3 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 ETN97829.1 - 2.5e-07 30.2 1.7 0.00013 21.9 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 ETN97829.1 - 1.6e-06 28.1 3.9 8.9e-05 22.6 0.0 3.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETN97829.1 - 2.5e-05 24.6 0.4 8.5e-05 22.9 0.3 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Toxin_43 PF15604.1 ETN97831.1 - 0.023 14.7 4.2 0.028 14.4 2.9 1.1 1 0 0 1 1 1 0 Putative toxin 43 INCENP_ARK-bind PF03941.10 ETN97831.1 - 0.051 13.4 3.3 0.077 12.8 2.3 1.4 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region Spt5_N PF11942.3 ETN97831.1 - 0.074 13.6 2.4 0.1 13.2 1.6 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal PH PF00169.24 ETN97832.1 - 0.00017 21.7 5.3 0.00017 21.7 3.7 2.2 2 1 0 2 2 2 1 PH domain PH_11 PF15413.1 ETN97832.1 - 0.00082 19.5 0.6 0.00082 19.5 0.4 2.5 2 2 0 2 2 2 1 Pleckstrin homology domain Secretin_N_2 PF07655.8 ETN97832.1 - 1.3 9.5 15.8 0.11 12.8 7.1 1.9 2 0 0 2 2 2 0 Secretin N-terminal domain VWA_2 PF13519.1 ETN97833.1 - 0.004 17.2 0.0 0.006 16.7 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 ETN97833.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Piwi PF02171.12 ETN97834.1 - 1.3e-21 76.8 0.0 1.7e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 Piwi domain WD40 PF00400.27 ETN97835.1 - 1.6e-13 49.9 2.5 2.5e-10 39.8 0.4 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETN97835.1 - 0.00091 17.4 0.1 0.0011 17.2 0.1 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 UMPH-1 PF05822.7 ETN97836.1 - 0.025 13.8 0.1 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) DNA_pol3_a_NII PF11490.3 ETN97836.1 - 2.9 7.5 9.5 0.16 11.6 1.8 2.3 3 0 0 3 3 3 0 DNA polymerase III polC-type N-terminus II Dala_Dala_lig_N PF01820.16 ETN97837.1 - 0.035 14.3 0.3 0.054 13.8 0.2 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Dna2 PF08696.6 ETN97837.1 - 0.1 11.8 1.2 0.12 11.6 0.8 1.1 1 0 0 1 1 1 0 DNA replication factor Dna2 DUF3619 PF12279.3 ETN97837.1 - 0.11 12.6 0.3 0.15 12.1 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3619) Peroxin-13_N PF04088.8 ETN97837.1 - 0.15 12.0 1.4 0.17 11.7 1.0 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DUF2763 PF10961.3 ETN97837.1 - 0.91 9.9 3.8 1.6 9.1 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2763) Prp18 PF02840.10 ETN97837.1 - 3 7.6 7.3 2.6 7.8 2.6 2.0 1 1 1 2 2 2 0 Prp18 domain PUB PF09409.5 ETN97838.1 - 0.035 13.8 0.8 0.057 13.1 0.3 1.5 1 1 0 1 1 1 0 PUB domain zf-TRAF PF02176.13 ETN97839.1 - 1.8e-05 25.0 5.2 3.6e-05 24.0 3.6 1.5 1 0 0 1 1 1 1 TRAF-type zinc finger Atg14 PF10186.4 ETN97839.1 - 0.011 14.7 1.1 0.011 14.7 0.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_TATA_bd PF12325.3 ETN97839.1 - 0.013 15.2 2.1 0.016 14.9 1.5 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF4435 PF14491.1 ETN97839.1 - 0.015 15.1 6.7 0.028 14.2 4.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4435) DUF972 PF06156.8 ETN97839.1 - 0.016 15.5 6.5 0.039 14.3 4.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF603 PF04645.7 ETN97839.1 - 0.024 14.6 1.9 0.031 14.2 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF603 HrpJ PF07201.6 ETN97839.1 - 0.057 13.4 3.0 0.07 13.1 2.1 1.1 1 0 0 1 1 1 0 HrpJ-like domain Cupin_4 PF08007.7 ETN97839.1 - 0.069 12.3 0.4 0.084 12.0 0.3 1.1 1 0 0 1 1 1 0 Cupin superfamily protein TPR_MLP1_2 PF07926.7 ETN97839.1 - 0.072 12.8 7.3 0.23 11.1 5.0 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4047 PF13256.1 ETN97839.1 - 0.09 12.7 4.7 0.15 12.0 3.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) DUF342 PF03961.8 ETN97839.1 - 0.11 10.9 4.3 0.13 10.7 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Bap31 PF05529.7 ETN97839.1 - 0.21 11.0 3.9 0.27 10.6 2.7 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DivIVA PF05103.8 ETN97839.1 - 0.24 11.4 7.5 0.48 10.4 1.4 2.0 1 1 1 2 2 2 0 DivIVA protein Tup_N PF08581.5 ETN97839.1 - 0.28 11.4 7.3 10 6.4 5.1 2.4 1 1 0 1 1 1 0 Tup N-terminal HR1 PF02185.11 ETN97839.1 - 0.29 10.9 9.5 1.1 9.0 0.9 2.3 1 1 1 2 2 2 0 Hr1 repeat FlxA PF14282.1 ETN97839.1 - 0.31 11.0 9.7 0.42 10.5 6.7 1.3 1 0 0 1 1 1 0 FlxA-like protein Csm1 PF12539.3 ETN97839.1 - 0.31 11.5 3.0 0.42 11.1 2.1 1.4 1 1 0 1 1 1 0 Chromosome segregation protein Csm1/Pcs1 Rabaptin PF03528.10 ETN97839.1 - 0.33 10.8 5.3 0.5 10.3 3.7 1.2 1 0 0 1 1 1 0 Rabaptin AAA_23 PF13476.1 ETN97839.1 - 0.35 11.1 6.7 0.4 10.9 4.7 1.1 1 0 0 1 1 1 0 AAA domain Imm5 PF14423.1 ETN97839.1 - 0.38 10.3 5.0 0.19 11.3 0.7 1.9 1 1 1 2 2 2 0 Immunity protein Imm5 bZIP_1 PF00170.16 ETN97839.1 - 0.4 10.6 7.3 4.3 7.3 0.3 2.3 1 1 1 2 2 2 0 bZIP transcription factor TSC22 PF01166.13 ETN97839.1 - 0.48 10.4 6.8 1.3 9.0 1.5 2.4 1 1 0 2 2 2 0 TSC-22/dip/bun family DUF3450 PF11932.3 ETN97839.1 - 0.68 9.1 5.3 0.81 8.8 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) IncA PF04156.9 ETN97839.1 - 1.3 8.5 5.5 1.9 8.0 3.8 1.3 1 0 0 1 1 1 0 IncA protein DUF4140 PF13600.1 ETN97839.1 - 1.6 9.2 4.3 8 6.9 0.2 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) AKNA PF12443.3 ETN97839.1 - 2.2 8.3 7.4 2.9 7.9 2.0 2.2 1 1 1 2 2 2 0 AT-hook-containing transcription factor SseC PF04888.7 ETN97839.1 - 3.9 6.7 4.8 5.2 6.2 3.4 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DivIC PF04977.10 ETN97839.1 - 4.3 6.8 12.4 8 6.0 2.9 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF904 PF06005.7 ETN97839.1 - 6.3 7.1 11.5 14 6.0 8.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF904) HEAT_2 PF13646.1 ETN97840.1 - 7e-13 48.6 0.0 1.7e-08 34.6 0.0 1.9 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 ETN97840.1 - 1.2e-10 40.5 0.0 0.00059 19.6 0.0 2.2 2 0 0 2 2 2 2 HEAT repeat HEAT_EZ PF13513.1 ETN97840.1 - 5e-06 26.8 0.0 0.0083 16.5 0.0 2.1 1 1 1 2 2 2 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 ETN97840.1 - 0.0025 18.1 0.1 0.29 11.5 0.0 1.9 1 1 1 2 2 2 2 Vacuolar 14 Fab1-binding region NLE PF08154.7 ETN97840.1 - 0.0047 16.8 0.3 0.034 14.1 0.1 2.3 1 1 1 2 2 2 1 NLE (NUC135) domain DUF3554 PF12074.3 ETN97840.1 - 0.014 14.8 0.1 0.096 12.0 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3554) HEAT_PBS PF03130.11 ETN97840.1 - 0.031 14.7 0.0 0.81 10.3 0.0 2.5 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat MOR2-PAG1_N PF14222.1 ETN97840.1 - 0.033 12.9 0.0 0.038 12.6 0.0 1.2 1 0 0 1 1 1 0 Cell morphogenesis N-terminal Flu_NS1 PF00600.14 ETN97840.1 - 0.034 13.2 0.1 2.2 7.3 0.0 2.0 1 1 1 2 2 2 0 Influenza non-structural protein (NS1) MutL_C PF08676.6 ETN97840.1 - 0.1 12.1 0.1 0.29 10.7 0.0 1.7 1 1 1 2 2 2 0 MutL C terminal dimerisation domain Proteasom_PSMB PF10508.4 ETN97840.1 - 0.11 10.7 0.1 0.15 10.3 0.1 1.2 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit CLASP_N PF12348.3 ETN97840.1 - 0.12 11.7 0.1 0.17 11.1 0.0 1.3 1 1 0 1 1 1 0 CLASP N terminal Fe-S_assembly PF04384.8 ETN97840.1 - 0.25 11.7 1.1 9.5 6.6 0.1 2.3 1 1 1 2 2 2 0 Iron-sulphur cluster assembly DUF2758 PF10957.3 ETN97840.1 - 0.25 11.1 1.6 1.9 8.3 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2758) Folate_carrier PF01770.13 ETN97841.1 - 0.021 13.3 1.3 0.03 12.8 0.9 1.2 1 0 0 1 1 1 0 Reduced folate carrier MGC-24 PF05283.6 ETN97841.1 - 0.063 13.0 4.0 0.11 12.2 2.8 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Atrophin-1 PF03154.10 ETN97843.1 - 0.0033 15.6 13.9 0.0036 15.5 9.6 1.0 1 0 0 1 1 1 1 Atrophin-1 family Presenilin PF01080.12 ETN97843.1 - 0.092 11.5 1.5 0.11 11.3 1.1 1.0 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.5 ETN97843.1 - 0.21 9.9 2.7 0.25 9.7 1.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ERK-JNK_inhib PF15002.1 ETN97843.1 - 0.35 10.2 9.8 0.45 9.8 6.8 1.2 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor Sec62 PF03839.11 ETN97843.1 - 0.56 9.5 10.8 0.66 9.3 7.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 CDC45 PF02724.9 ETN97843.1 - 0.89 7.5 6.6 0.96 7.3 4.6 1.1 1 0 0 1 1 1 0 CDC45-like protein PrmA PF06325.8 ETN97843.1 - 0.89 8.6 7.3 1.1 8.3 5.0 1.0 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) SMN PF06003.7 ETN97843.1 - 1.4 7.9 5.6 1.8 7.5 3.8 1.3 1 1 0 1 1 1 0 Survival motor neuron protein (SMN) Thg1C PF14413.1 ETN97843.1 - 1.6 8.4 8.7 1.1 8.8 5.1 1.5 1 1 0 1 1 1 0 Thg1 C terminal domain MRP-L46 PF11788.3 ETN97843.1 - 2.1 9.0 8.9 4 8.1 6.2 1.4 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 Ycf1 PF05758.7 ETN97843.1 - 4.6 4.8 9.0 4.8 4.7 6.2 1.0 1 0 0 1 1 1 0 Ycf1 DUF3899 PF13038.1 ETN97843.1 - 9.2 6.4 5.7 14 5.9 2.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) DUF1647 PF07801.6 ETN97844.1 - 0.024 14.1 2.0 0.032 13.7 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1647) zf-H2C2_5 PF13909.1 ETN97844.1 - 0.14 12.4 0.6 16 5.9 0.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain WD40 PF00400.27 ETN97845.1 - 7.2e-09 35.1 2.3 7e-08 32.0 0.4 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETN97845.1 - 1e-05 23.9 0.1 1.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 HSF_DNA-bind PF00447.12 ETN97847.1 - 0.089 12.9 1.0 3.1 7.9 0.1 2.1 1 1 1 2 2 2 0 HSF-type DNA-binding Peptidase_C14 PF00656.17 ETN97848.1 - 0.00036 20.3 0.0 0.00044 20.0 0.0 1.1 1 0 0 1 1 1 1 Caspase domain COesterase PF00135.23 ETN97848.1 - 0.058 12.1 0.0 0.058 12.0 0.0 1.0 1 0 0 1 1 1 0 Carboxylesterase family Peptidase_S49_N PF08496.5 ETN97849.1 - 0.01 15.6 0.8 0.014 15.1 0.6 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal WD40 PF00400.27 ETN97850.1 - 1.3e-28 97.7 5.1 1.3e-09 37.5 0.0 4.3 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN97850.1 - 0.0011 17.2 0.4 0.17 10.0 0.0 2.6 1 1 1 2 2 2 2 Nucleoporin Nup120/160 WD40 PF00400.27 ETN97851.1 - 1.3e-55 183.3 8.6 5.1e-15 54.6 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat PQQ_2 PF13360.1 ETN97851.1 - 1.6e-08 34.3 0.2 0.00076 19.0 0.0 2.0 1 1 1 2 2 2 2 PQQ-like domain eIF2A PF08662.6 ETN97851.1 - 4.3e-08 33.1 0.0 0.00011 21.9 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETN97851.1 - 9.6e-07 27.3 0.0 0.24 9.5 0.0 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 PD40 PF07676.7 ETN97851.1 - 5.7e-06 25.8 3.9 5.1 6.8 0.0 4.4 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 ETN97851.1 - 7.5e-06 25.1 2.9 4.9 6.5 0.0 4.7 4 0 0 4 4 4 1 Proteasome subunit A N-terminal signature Gmad1 PF10647.4 ETN97851.1 - 5.4e-05 22.7 0.0 0.018 14.4 0.0 3.1 1 1 1 2 2 2 2 Lipoprotein LpqB beta-propeller domain Cytochrom_D1 PF02239.11 ETN97851.1 - 8.2e-05 21.0 0.1 0.00049 18.5 0.0 2.1 1 1 2 3 3 3 1 Cytochrome D1 heme domain DUF1258 PF06869.7 ETN97851.1 - 9.3e-05 21.6 0.0 4.5 6.2 0.0 3.7 1 1 3 4 4 4 2 Protein of unknown function (DUF1258) DPPIV_N PF00930.16 ETN97851.1 - 0.00069 18.3 0.0 0.98 7.9 0.0 3.3 1 1 1 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region NYD-SP28_assoc PF14775.1 ETN97851.1 - 0.0011 18.5 0.0 4.5 7.0 0.0 3.6 4 0 0 4 4 4 1 Sperm tail C-terminal domain PQQ_3 PF13570.1 ETN97851.1 - 0.0018 18.4 0.0 1 9.7 0.0 2.8 2 1 1 3 3 3 1 PQQ-like domain Me-amine-dh_H PF06433.6 ETN97851.1 - 0.0065 15.1 0.0 0.16 10.5 0.0 2.2 1 1 1 2 2 2 1 Methylamine dehydrogenase heavy chain (MADH) Mid2 PF04478.7 ETN97851.1 - 0.0085 15.5 0.5 1.8 7.9 0.0 3.0 1 1 2 3 3 3 1 Mid2 like cell wall stress sensor PLD_C PF12357.3 ETN97851.1 - 0.019 14.4 0.4 16 5.1 0.0 3.8 1 1 2 4 4 4 0 Phospholipase D C terminal SGL PF08450.7 ETN97851.1 - 0.022 14.1 0.0 0.077 12.3 0.0 2.1 1 1 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region DUF3312 PF11768.3 ETN97851.1 - 0.042 12.0 0.0 1 7.5 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3312) SLH PF00395.15 ETN97851.1 - 0.13 12.0 0.2 12 5.7 0.0 3.2 3 0 0 3 3 3 0 S-layer homology domain Luteo_P1-P2 PF08467.5 ETN97853.1 - 0.067 11.9 6.3 0.075 11.8 4.4 1.0 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase Exonuc_VII_L PF02601.10 ETN97853.1 - 6.3 5.8 13.2 7.2 5.6 9.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit RNA_pol_Rpb2_1 PF04563.10 ETN97854.1 - 0.024 13.5 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase beta subunit Choline_sulf_C PF12411.3 ETN97855.1 - 0.024 14.4 0.2 0.044 13.6 0.2 1.4 1 0 0 1 1 1 0 Choline sulfatase enzyme C terminal DUF3267 PF11667.3 ETN97855.1 - 0.025 14.7 0.7 0.046 13.9 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3267) zf-TRAF PF02176.13 ETN97856.1 - 0.0014 18.9 1.8 0.0014 18.9 1.2 3.2 3 1 0 3 3 3 1 TRAF-type zinc finger zf-BED PF02892.10 ETN97856.1 - 0.062 13.0 2.9 1.1 9.0 0.2 2.8 2 0 0 2 2 2 0 BED zinc finger zf-H2C2_5 PF13909.1 ETN97856.1 - 0.45 10.8 0.1 0.45 10.8 0.0 3.4 3 1 0 3 3 3 0 C2H2-type zinc-finger domain WD40 PF00400.27 ETN97857.1 - 1.2e-05 24.9 0.5 3.5e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 WD domain, G-beta repeat MAPKK1_Int PF08923.5 ETN97858.1 - 0.098 12.2 0.1 0.17 11.5 0.0 1.5 1 1 0 1 1 1 0 Mitogen-activated protein kinase kinase 1 interacting DUF4518 PF15008.1 ETN97860.1 - 0.025 13.5 0.1 0.029 13.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) WD40 PF00400.27 ETN97861.1 - 8.2e-16 57.2 9.4 5.1e-09 35.6 0.7 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETN97861.1 - 0.036 12.3 0.0 0.063 11.5 0.0 1.5 1 1 0 1 1 1 0 Cytochrome D1 heme domain Big_3 PF07523.7 ETN97861.1 - 0.11 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) HSP70 PF00012.15 ETN97862.1 - 1.2e-42 145.7 0.0 1.4e-42 145.4 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein DUF4578 PF15147.1 ETN97867.1 - 0.06 13.7 2.3 0.064 13.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4578) MDFI PF15316.1 ETN97867.1 - 0.091 12.7 2.6 0.13 12.2 1.8 1.2 1 0 0 1 1 1 0 MyoD family inhibitor DUF3464 PF11947.3 ETN97867.1 - 0.14 11.5 2.5 0.28 10.6 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Myosin_tail_1 PF01576.14 ETN97868.1 - 0.038 11.7 57.5 0.0042 14.8 21.9 2.5 1 1 1 2 2 2 0 Myosin tail Reo_sigmaC PF04582.7 ETN97868.1 - 0.44 9.6 11.6 0.86 8.7 2.4 2.4 1 1 0 2 2 2 0 Reovirus sigma C capsid protein DUF812 PF05667.6 ETN97868.1 - 5 5.5 53.8 2.6 6.4 18.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF812) LMF1 PF06762.9 ETN97869.1 - 2.7e-23 82.4 0.6 3.8e-22 78.6 0.4 2.0 1 1 0 1 1 1 1 Lipase maturation factor Kelch_4 PF13418.1 ETN97872.1 - 0.12 12.2 0.2 2 8.2 0.0 2.5 2 0 0 2 2 2 0 Galactose oxidase, central domain TauE PF01925.14 ETN97873.1 - 0.011 15.2 1.3 0.013 15.0 0.9 1.0 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE DUF2651 PF10852.3 ETN97874.1 - 0.12 12.7 3.0 0.13 12.6 1.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2651) DUF912 PF06024.7 ETN97875.1 - 0.34 10.9 0.0 0.34 10.9 0.0 3.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Utp14 PF04615.8 ETN97875.1 - 2.4 6.2 15.8 3 5.8 10.9 1.1 1 0 0 1 1 1 0 Utp14 protein Tim54 PF11711.3 ETN97875.1 - 2.9 6.4 6.7 3.8 5.9 4.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2330 PF10092.4 ETN97876.1 - 2.3e-76 256.9 0.8 6.5e-75 252.1 0.5 2.0 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2330) zf-TRAF PF02176.13 ETN97877.1 - 1.4e-05 25.3 1.3 1.4e-05 25.3 0.9 2.2 2 2 0 2 2 2 1 TRAF-type zinc finger HDA2-3 PF11496.3 ETN97878.1 - 0.022 13.6 1.8 0.021 13.6 1.3 1.1 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 DUF4137 PF13593.1 ETN97878.1 - 0.023 13.7 0.1 0.027 13.5 0.1 1.0 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) Nop53 PF07767.6 ETN97878.1 - 0.041 12.8 10.0 0.041 12.8 6.9 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF1168 PF06658.7 ETN97878.1 - 0.075 12.5 13.8 0.1 12.1 9.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) SR-25 PF10500.4 ETN97878.1 - 7.3 5.9 17.7 10 5.5 12.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein WAK PF08488.6 ETN97879.1 - 0.007 16.6 1.2 0.0084 16.4 0.8 1.2 1 0 0 1 1 1 1 Wall-associated kinase Toxin_30 PF08117.6 ETN97880.1 - 0.22 11.6 1.9 0.37 10.8 1.3 1.3 1 0 0 1 1 1 0 Ptu family PPR_2 PF13041.1 ETN97881.1 - 0.14 12.1 0.4 0.29 11.1 0.0 1.7 2 0 0 2 2 2 0 PPR repeat family VAR1 PF05316.7 ETN97882.1 - 0.023 13.2 3.5 0.024 13.2 2.4 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein (VAR1) SPOB_ab PF14682.1 ETN97882.1 - 0.083 12.6 0.5 0.088 12.6 0.3 1.1 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal Cys_rich_VLP PF14194.1 ETN97882.1 - 0.13 11.9 0.9 0.21 11.3 0.6 1.3 1 0 0 1 1 1 0 Cysteine-rich VLP V-set PF07686.12 ETN97882.1 - 0.13 12.1 0.1 0.17 11.7 0.1 1.2 1 0 0 1 1 1 0 Immunoglobulin V-set domain Gemini_C4 PF01492.12 ETN97884.1 - 0.0079 15.8 0.2 0.011 15.4 0.1 1.2 1 0 0 1 1 1 1 Geminivirus C4 protein Baculo_IE-1 PF05290.6 ETN97885.1 - 0.036 13.8 3.9 0.05 13.3 2.7 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) LytTR PF04397.10 ETN97886.1 - 0.13 12.3 1.3 0.18 11.8 0.9 1.2 1 0 0 1 1 1 0 LytTr DNA-binding domain DUF479 PF04336.7 ETN97886.1 - 0.14 12.2 1.4 7.2 6.7 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF479 Ham1p_like PF01725.11 ETN97886.1 - 0.31 10.3 2.6 3.8 6.8 1.8 2.0 1 1 0 1 1 1 0 Ham1 family DUF3903 PF13043.1 ETN97886.1 - 2.7 7.5 7.4 1.1 8.8 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3903) CAP_GLY PF01302.20 ETN97887.1 - 0.00042 19.9 0.0 0.00088 18.9 0.0 1.6 1 0 0 1 1 1 1 CAP-Gly domain hNIFK_binding PF12196.3 ETN97887.1 - 7.5 6.0 6.8 8.6 5.8 3.4 2.0 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK BCAS2 PF05700.6 ETN97888.1 - 0.002 17.6 4.5 0.0032 16.9 2.6 1.7 1 1 1 2 2 2 1 Breast carcinoma amplified sequence 2 (BCAS2) DUF3416 PF11896.3 ETN97888.1 - 0.0046 16.9 0.0 0.0053 16.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3416) Tetraspannin PF00335.15 ETN97888.1 - 0.016 14.4 1.5 0.029 13.6 1.0 1.4 1 0 0 1 1 1 0 Tetraspanin family DUF3994 PF13159.1 ETN97888.1 - 0.024 14.8 0.7 0.07 13.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3994) MLANA PF14991.1 ETN97888.1 - 0.03 14.3 0.1 0.051 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein melan-A DUF1395 PF07160.7 ETN97888.1 - 0.037 13.5 1.2 0.042 13.3 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1395) MRL1 PF13003.2 ETN97888.1 - 0.076 12.8 0.3 0.14 11.9 0.2 1.5 1 0 0 1 1 1 0 Ribosomal protein L1 LepA_C PF06421.7 ETN97888.1 - 0.09 12.6 0.6 0.78 9.6 0.0 2.0 1 1 1 2 2 2 0 GTP-binding protein LepA C-terminus Orthoreo_P10 PF07204.6 ETN97888.1 - 2.1 8.1 4.2 4.7 7.0 2.9 1.7 1 1 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 FAM163 PF15069.1 ETN97888.1 - 8.5 6.9 7.9 0.93 10.0 1.5 2.0 1 1 1 2 2 2 0 FAM163 family TBX PF12598.3 ETN97889.1 - 0.019 15.3 5.4 0.027 14.8 3.8 1.2 1 0 0 1 1 1 0 T-box transcription factor DUF1777 PF08648.7 ETN97889.1 - 0.1 12.3 11.6 0.11 12.2 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) SUFU_C PF12470.3 ETN97889.1 - 0.26 10.8 1.8 0.28 10.7 1.2 1.1 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain RNA_pol_Rpc4 PF05132.9 ETN97889.1 - 0.56 10.1 3.8 0.68 9.9 2.7 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 YqfQ PF14181.1 ETN97889.1 - 2.9 7.9 6.6 3.9 7.5 4.6 1.2 1 0 0 1 1 1 0 YqfQ-like protein Dsh_C PF12316.3 ETN97889.1 - 4.5 7.3 5.8 5 7.1 4.0 1.0 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Sec62 PF03839.11 ETN97889.1 - 4.8 6.5 7.5 4.7 6.5 5.2 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 FliD_N PF02465.13 ETN97890.1 - 0.0045 17.3 3.9 0.0053 17.0 2.7 1.2 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 N-terminus BLOC1_2 PF10046.4 ETN97890.1 - 0.0067 16.5 3.6 0.0067 16.5 2.5 1.6 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Rop-like PF05082.8 ETN97890.1 - 0.014 14.8 1.5 1.3 8.5 0.1 2.5 2 1 0 2 2 2 0 Rop-like Med15_fungi PF05397.7 ETN97890.1 - 0.023 14.6 4.2 0.025 14.5 2.8 1.3 1 1 0 1 1 1 0 Mediator complex subunit 15 DUF4200 PF13863.1 ETN97890.1 - 0.025 14.5 1.5 0.025 14.5 1.1 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) DIM1 PF02966.11 ETN97890.1 - 0.032 13.7 0.2 0.032 13.7 0.1 1.4 2 0 0 2 2 1 0 Mitosis protein DIM1 bZIP_2 PF07716.10 ETN97890.1 - 0.05 13.4 1.3 0.05 13.4 0.9 1.7 2 0 0 2 2 1 0 Basic region leucine zipper Sas10_Utp3 PF04000.10 ETN97890.1 - 0.061 13.5 1.0 0.11 12.7 0.7 1.5 1 0 0 1 1 1 0 Sas10/Utp3/C1D family YscO PF07321.7 ETN97890.1 - 0.062 13.1 2.6 0.087 12.6 1.8 1.2 1 1 0 1 1 1 0 Type III secretion protein YscO Fib_alpha PF08702.5 ETN97890.1 - 0.064 13.3 6.1 0.046 13.8 3.4 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Mnd1 PF03962.10 ETN97890.1 - 0.082 12.5 4.1 0.096 12.3 2.9 1.1 1 0 0 1 1 1 0 Mnd1 family Spectrin PF00435.16 ETN97890.1 - 0.086 13.1 4.3 0.12 12.7 3.0 1.3 1 1 0 1 1 1 0 Spectrin repeat DUF4407 PF14362.1 ETN97890.1 - 0.095 11.6 1.1 0.099 11.5 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2232 PF09991.4 ETN97890.1 - 0.1 11.5 1.3 0.13 11.2 0.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) MRP-S27 PF10037.4 ETN97890.1 - 0.11 11.3 3.5 0.12 11.3 2.4 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 CHD5 PF04420.9 ETN97890.1 - 0.12 12.0 0.5 0.13 11.9 0.3 1.3 1 0 0 1 1 1 0 CHD5-like protein DUF3573 PF12097.3 ETN97890.1 - 0.13 10.8 4.2 0.12 10.9 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DivIC PF04977.10 ETN97890.1 - 0.13 11.7 5.4 0.29 10.6 3.7 1.8 1 1 0 1 1 1 0 Septum formation initiator DASH_Dam1 PF08653.5 ETN97890.1 - 0.14 11.9 0.2 0.3 10.8 0.1 1.6 1 1 0 1 1 1 0 DASH complex subunit Dam1 DUF2730 PF10805.3 ETN97890.1 - 0.18 11.5 2.2 0.23 11.2 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Reo_sigmaC PF04582.7 ETN97890.1 - 0.21 10.7 1.3 0.2 10.7 0.9 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DivIVA PF05103.8 ETN97890.1 - 0.22 11.5 6.2 0.13 12.2 1.5 1.9 1 1 1 2 2 2 0 DivIVA protein FlxA PF14282.1 ETN97890.1 - 0.42 10.5 13.0 0.46 10.4 8.6 1.4 1 1 0 1 1 1 0 FlxA-like protein Seryl_tRNA_N PF02403.17 ETN97890.1 - 0.51 10.3 8.9 0.44 10.5 4.4 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FlaC_arch PF05377.6 ETN97890.1 - 0.72 9.7 4.8 0.62 10.0 1.5 2.3 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Syntaxin PF00804.20 ETN97890.1 - 0.91 9.7 8.6 3.2 7.9 5.7 1.9 1 1 0 1 1 1 0 Syntaxin GLE1 PF07817.8 ETN97890.1 - 1.2 7.9 4.7 1.4 7.7 3.3 1.1 1 0 0 1 1 1 0 GLE1-like protein Fzo_mitofusin PF04799.8 ETN97890.1 - 1.3 8.3 4.6 1.4 8.2 3.2 1.1 1 0 0 1 1 1 0 fzo-like conserved region Neur_chan_memb PF02932.11 ETN97891.1 - 0.93 9.3 6.1 1.2 8.9 4.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Auxin_canalis PF05703.6 ETN97891.1 - 1.8 8.3 7.4 2.7 7.7 5.1 1.2 1 0 0 1 1 1 0 Auxin canalisation TIP_N PF12457.3 ETN97891.1 - 8.5 6.4 15.9 6.8 6.8 2.7 2.4 1 1 1 2 2 2 0 Tuftelin interacting protein N terminal zf-CpG_bind_C PF12269.3 ETN97893.1 - 0.0081 15.6 7.4 0.0087 15.5 5.1 1.0 1 0 0 1 1 1 1 CpG binding protein zinc finger C terminal domain Pterin_4a PF01329.14 ETN97893.1 - 0.029 14.1 0.5 0.036 13.8 0.4 1.1 1 0 0 1 1 1 0 Pterin 4 alpha carbinolamine dehydratase MAP7 PF05672.6 ETN97893.1 - 0.63 9.4 5.5 0.8 9.0 3.8 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Phage_Mu_Gam PF07352.7 ETN97893.1 - 2.8 7.4 13.0 0.58 9.6 5.5 1.8 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein NOP5NT PF08156.8 ETN97893.1 - 4 7.6 5.6 4.2 7.6 1.7 2.3 1 1 1 2 2 2 0 NOP5NT (NUC127) domain DUSP PF06337.7 ETN97893.1 - 6.6 7.2 8.2 11 6.4 5.7 1.5 1 1 0 1 1 1 0 DUSP domain Ribosomal_L19 PF01245.15 ETN97894.1 - 1.6e-10 40.7 0.1 1.9e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L19 NACHT PF05729.7 ETN97895.1 - 0.073 12.7 0.0 0.099 12.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Peptidase_C14 PF00656.17 ETN97896.1 - 4.4e-10 39.6 0.2 1.3e-09 38.0 0.2 1.7 1 1 0 1 1 1 1 Caspase domain Phospholip_A2_2 PF05826.7 ETN97896.1 - 0.042 13.8 0.1 0.074 13.0 0.1 1.4 1 0 0 1 1 1 0 Phospholipase A2 FAM117 PF15388.1 ETN97897.1 - 0.054 12.7 3.5 0.07 12.3 2.4 1.1 1 0 0 1 1 1 0 Protein Family FAM117 TMEM237 PF15383.1 ETN97897.1 - 0.077 12.1 3.8 0.098 11.7 2.3 1.4 1 1 1 2 2 2 0 Transmembrane protein 237 SR-25 PF10500.4 ETN97897.1 - 0.11 11.9 13.9 0.047 13.1 8.2 1.5 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein ICMT PF04140.9 ETN97898.1 - 0.014 15.5 0.1 0.014 15.5 0.1 2.0 2 1 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family TIP120 PF08623.5 ETN97900.1 - 0.0012 18.4 0.0 0.0013 18.3 0.0 1.0 1 0 0 1 1 1 1 TATA-binding protein interacting (TIP20) XkdW PF09636.5 ETN97900.1 - 0.0018 18.1 0.0 0.002 17.9 0.0 1.0 1 0 0 1 1 1 1 XkdW protein HEAT_2 PF13646.1 ETN97900.1 - 0.0045 17.2 0.1 0.0084 16.3 0.1 1.4 1 1 0 1 1 1 1 HEAT repeats HEAT PF02985.17 ETN97900.1 - 0.024 14.7 0.0 1.5 9.0 0.0 2.6 3 0 0 3 3 3 0 HEAT repeat TENA_THI-4 PF03070.11 ETN97900.1 - 0.059 13.1 0.0 0.067 12.9 0.0 1.0 1 0 0 1 1 1 0 TENA/THI-4/PQQC family RestrictionMunI PF11407.3 ETN97900.1 - 0.12 11.9 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Type II restriction enzyme MunI DUF3959 PF13105.1 ETN97901.1 - 0.031 13.6 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) NTR PF01759.16 ETN97901.1 - 0.19 11.2 1.9 2.4 7.7 0.0 2.2 2 0 0 2 2 2 0 UNC-6/NTR/C345C module zf-TRAF PF02176.13 ETN97902.1 - 2.7e-06 27.6 1.1 2.7e-06 27.6 0.8 3.1 4 0 0 4 4 4 1 TRAF-type zinc finger WD40 PF00400.27 ETN97902.1 - 0.004 16.9 0.6 0.004 16.9 0.4 3.6 5 0 0 5 5 5 1 WD domain, G-beta repeat TPR_12 PF13424.1 ETN97903.1 - 4.8e-31 106.5 1.3 4.5e-14 52.1 0.0 3.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETN97903.1 - 1.3e-17 63.2 4.2 2.3e-10 39.9 0.3 3.1 3 0 0 3 3 3 3 TPR repeat TPR_10 PF13374.1 ETN97903.1 - 1.8e-16 59.4 0.0 0.0037 17.1 0.0 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETN97903.1 - 5.1e-14 50.9 22.2 0.00015 21.3 0.4 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETN97903.1 - 9.5e-14 50.3 18.5 5e-05 22.7 0.3 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETN97903.1 - 3.1e-13 48.4 0.9 0.0058 16.3 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETN97903.1 - 5.5e-11 41.7 3.0 0.16 12.2 0.1 4.6 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETN97903.1 - 1.9e-09 36.6 13.0 0.00072 19.2 0.2 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETN97903.1 - 1.1e-06 28.7 0.7 0.19 12.2 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 ETN97903.1 - 0.00035 20.6 4.8 0.16 12.1 0.2 2.9 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 ETN97903.1 - 0.00046 20.5 0.0 0.68 10.7 0.0 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.7 ETN97903.1 - 0.00052 19.7 6.7 0.084 12.7 0.3 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETN97903.1 - 0.00062 20.3 0.0 0.37 11.5 0.0 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat Mob_Pre PF01076.14 ETN97903.1 - 0.0015 18.1 0.8 0.002 17.7 0.1 1.5 2 0 0 2 2 2 1 Plasmid recombination enzyme PPR PF01535.15 ETN97903.1 - 0.002 18.0 7.8 0.38 10.8 0.1 3.8 4 0 0 4 4 4 2 PPR repeat KH_4 PF13083.1 ETN97903.1 - 0.0028 17.2 0.3 0.53 9.9 0.0 3.0 3 1 0 3 3 3 1 KH domain MIT PF04212.13 ETN97903.1 - 1.1 9.1 5.8 4.3 7.2 0.0 2.9 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain DUF3192 PF11399.3 ETN97904.1 - 0.57 10.1 3.8 1.1 9.2 2.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3192) BAF1_ABF1 PF04684.8 ETN97905.1 - 0.11 11.3 3.2 0.13 11.0 2.2 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor ECH_C PF13766.1 ETN97906.1 - 7.7e-34 116.3 0.1 1.2e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 ETN97906.1 - 6.4e-14 51.6 0.0 2.8e-13 49.5 0.0 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Pkinase PF00069.20 ETN97908.1 - 3.1e-12 46.2 0.0 3.9e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain PH_11 PF15413.1 ETN97909.1 - 0.0038 17.4 0.6 0.057 13.6 0.2 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 ETN97909.1 - 0.0052 16.9 2.0 0.25 11.5 0.3 3.2 3 1 0 3 3 3 1 PH domain PH_6 PF15406.1 ETN97909.1 - 0.0087 16.1 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 ETN97909.1 - 0.036 13.9 0.0 0.089 12.6 0.0 1.7 1 0 0 1 1 1 0 PH domain YHYH PF14240.1 ETN97910.1 - 0.0068 16.0 0.1 0.0091 15.6 0.1 1.4 1 0 0 1 1 1 1 YHYH protein PP2C_2 PF13672.1 ETN97911.1 - 0.055 12.8 0.1 0.083 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein phosphatase 2C LysE PF01810.13 ETN97911.1 - 0.11 11.7 0.4 0.18 11.0 0.2 1.4 1 1 0 1 1 1 0 LysE type translocator Frigida PF07899.6 ETN97913.1 - 0.0077 15.0 0.1 0.011 14.5 0.0 1.1 1 0 0 1 1 1 1 Frigida-like protein zf-TRAF PF02176.13 ETN97914.1 - 5e-05 23.5 4.2 9.1e-05 22.7 2.9 1.5 1 0 0 1 1 1 1 TRAF-type zinc finger DUF4200 PF13863.1 ETN97914.1 - 0.0012 18.8 4.0 0.0015 18.5 2.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) UBN_AB PF14075.1 ETN97914.1 - 0.021 14.4 5.0 0.024 14.3 3.5 1.0 1 0 0 1 1 1 0 Ubinuclein conserved middle domain RSD-2 PF07547.8 ETN97914.1 - 0.15 12.2 0.9 0.27 11.4 0.6 1.4 1 0 0 1 1 1 0 RSD-2 N-terminal domain ACT_5 PF13710.1 ETN97914.1 - 2.2 8.1 4.4 0.38 10.5 0.4 1.7 2 0 0 2 2 2 0 ACT domain DivIC PF04977.10 ETN97914.1 - 3.1 7.3 7.4 4.1 6.9 4.8 1.5 1 1 0 1 1 1 0 Septum formation initiator Spore_SspJ PF09575.5 ETN97916.1 - 0.013 15.6 7.3 0.15 12.3 0.3 2.2 2 0 0 2 2 2 0 Small spore protein J (Spore_SspJ) DUF3138 PF11336.3 ETN97916.1 - 0.2 9.7 9.2 0.23 9.6 6.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Mucin PF01456.12 ETN97916.1 - 0.38 10.5 19.6 0.44 10.3 13.6 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2057 PF09829.4 ETN97916.1 - 0.79 9.3 10.1 0.94 9.1 7.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) LUC7 PF03194.10 ETN97916.1 - 1.4 8.3 5.7 1.8 8.0 3.9 1.2 1 0 0 1 1 1 0 LUC7 N_terminus DUF3439 PF11921.3 ETN97916.1 - 2.4 7.9 6.7 2.6 7.7 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) EcsC PF12787.2 ETN97916.1 - 2.5 7.4 6.1 3.5 6.9 4.2 1.2 1 0 0 1 1 1 0 EcsC protein family SSP160 PF06933.6 ETN97916.1 - 3.1 5.6 10.9 3.3 5.5 7.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3453 PF11935.3 ETN97917.1 - 0.016 14.5 0.1 0.016 14.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3453) Flavodoxin_1 PF00258.20 ETN97918.1 - 1.1e-15 57.9 0.1 1.7e-15 57.2 0.1 1.3 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.2 ETN97918.1 - 0.0034 17.3 0.4 0.011 15.6 0.1 1.8 2 0 0 2 2 2 1 Flavodoxin domain FAD_binding_1 PF00667.15 ETN97918.1 - 0.075 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain BRF1 PF07741.8 ETN97918.1 - 1.6 8.9 10.7 2 8.6 2.7 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain RelA_SpoT PF04607.12 ETN97919.1 - 0.00053 19.9 0.6 0.0013 18.7 0.4 1.7 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins Peptidase_M15 PF01427.12 ETN97920.1 - 0.054 13.0 0.0 0.062 12.8 0.0 1.2 1 0 0 1 1 1 0 D-ala-D-ala dipeptidase SipA PF09052.5 ETN97920.1 - 0.055 11.8 0.8 0.058 11.7 0.6 1.0 1 0 0 1 1 1 0 Salmonella invasion protein A Rootletin PF15035.1 ETN97922.1 - 0.054 13.4 0.3 0.064 13.2 0.2 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Scaffolding_pro PF11418.3 ETN97922.1 - 0.26 11.6 3.3 2.6 8.4 0.3 2.1 1 1 1 2 2 2 0 Phi29 scaffolding protein Skp1_POZ PF03931.10 ETN97923.1 - 0.016 15.2 0.1 0.059 13.4 0.0 1.9 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain Presenilin PF01080.12 ETN97923.1 - 1.8 7.2 10.1 0.5 9.1 4.9 1.5 1 1 1 2 2 2 0 Presenilin DUF3912 PF13051.1 ETN97924.1 - 0.074 12.8 0.1 7.5 6.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3912) WD40 PF00400.27 ETN97926.1 - 0.03 14.2 0.1 0.22 11.4 0.0 2.2 2 0 0 2 2 2 0 WD domain, G-beta repeat DUF724 PF05266.9 ETN97926.1 - 0.38 10.3 9.6 0.6 9.7 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) WD40 PF00400.27 ETN97927.1 - 7.4e-40 133.4 14.9 1.1e-08 34.6 1.9 5.5 5 1 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETN97927.1 - 2.1e-05 22.8 7.8 0.0023 16.1 1.1 3.4 2 2 2 4 4 4 3 Nucleoporin Nup120/160 Archaeal_AmoA PF12942.2 ETN97927.1 - 0.025 14.3 0.2 0.056 13.2 0.1 1.5 1 0 0 1 1 1 0 Archaeal ammonia monooxygenase subunit A (AmoA) Cytochrom_C_asm PF01578.15 ETN97929.1 - 0.088 12.3 1.4 0.11 12.0 0.8 1.3 1 1 0 1 1 1 0 Cytochrome C assembly protein TPR_12 PF13424.1 ETN97930.1 - 6.9e-61 202.1 26.5 1.3e-23 82.7 1.5 3.9 1 1 2 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETN97930.1 - 1.1e-51 172.2 47.1 5.3e-16 58.0 5.5 4.1 1 1 3 4 4 4 4 TPR repeat TPR_1 PF00515.23 ETN97930.1 - 1e-43 145.1 41.9 3e-10 39.2 2.0 6.1 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.1 ETN97930.1 - 3.8e-41 137.8 0.1 1.3e-06 28.1 0.0 6.0 5 1 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETN97930.1 - 3.2e-37 123.4 33.8 4.6e-09 35.4 0.5 6.0 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETN97930.1 - 3.3e-32 107.8 43.3 9.5e-09 34.4 3.4 6.1 5 1 0 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.1 ETN97930.1 - 3.9e-27 91.8 14.7 3.3e-05 23.3 0.0 6.1 5 1 0 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.1 ETN97930.1 - 2.3e-22 79.1 4.8 2.1e-09 37.8 0.0 4.5 2 1 1 4 4 4 4 Tetratricopeptide repeat TPR_6 PF13174.1 ETN97930.1 - 3.7e-21 74.0 12.3 1.6e-05 25.0 0.2 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETN97930.1 - 4.5e-19 67.2 0.0 0.0013 19.1 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETN97930.1 - 4.7e-17 60.7 27.3 0.0066 16.5 1.8 7.0 5 3 1 6 6 6 5 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETN97930.1 - 3.6e-13 48.5 1.5 0.00023 20.3 0.0 5.0 5 0 0 5 5 5 2 SHNi-TPR Apc3 PF12895.2 ETN97930.1 - 1.8e-10 40.8 25.7 0.00058 19.9 2.1 4.2 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETN97930.1 - 5.7e-10 39.3 4.0 0.0026 18.0 0.3 4.4 1 1 3 5 5 5 3 Tetratricopeptide repeat SNAP PF14938.1 ETN97930.1 - 8.6e-09 34.9 13.9 2.7e-05 23.4 6.2 2.9 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP MIT PF04212.13 ETN97930.1 - 6e-08 32.4 20.4 0.00058 19.6 0.6 5.1 5 0 0 5 5 5 3 MIT (microtubule interacting and transport) domain Sel1 PF08238.7 ETN97930.1 - 9e-07 29.3 21.8 0.15 12.7 0.3 5.4 5 0 0 5 5 5 3 Sel1 repeat DUF2225 PF09986.4 ETN97930.1 - 9e-06 25.3 16.4 0.0023 17.4 4.8 2.5 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) SPO22 PF08631.5 ETN97930.1 - 7.7e-05 21.9 13.1 0.67 8.9 0.5 5.0 4 1 1 5 5 5 1 Meiosis protein SPO22/ZIP4 like DUF627 PF04781.7 ETN97930.1 - 0.00013 21.5 11.6 0.99 9.0 0.4 4.4 1 1 3 4 4 4 2 Protein of unknown function (DUF627) TPR_5 PF12688.2 ETN97930.1 - 0.00037 20.4 0.8 0.0059 16.6 0.2 2.9 2 1 1 3 3 3 1 Tetratrico peptide repeat Prefoldin PF02996.12 ETN97930.1 - 0.0061 16.2 9.9 12 5.5 0.0 4.6 4 1 1 5 5 5 0 Prefoldin subunit BRO1 PF03097.13 ETN97930.1 - 0.0091 14.7 9.2 0.0079 14.9 3.8 2.5 1 1 1 2 2 2 1 BRO1-like domain PPR PF01535.15 ETN97930.1 - 0.023 14.6 7.8 7.5 6.7 0.0 5.7 5 2 1 6 6 6 0 PPR repeat RPN7 PF10602.4 ETN97930.1 - 0.036 13.4 14.4 0.94 8.8 0.4 4.2 2 2 2 4 4 4 0 26S proteasome subunit RPN7 TPR_3 PF07720.7 ETN97930.1 - 0.087 12.6 35.5 0.15 11.8 1.9 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat DUF2383 PF09537.5 ETN97930.1 - 0.28 11.4 0.1 0.28 11.4 0.1 2.0 4 0 0 4 4 1 0 Domain of unknown function (DUF2383) ATP13 PF12921.2 ETN97930.1 - 0.51 9.7 3.6 11 5.3 0.1 3.7 4 0 0 4 4 4 0 Mitochondrial ATPase expression NSF PF02071.15 ETN97930.1 - 0.71 10.6 12.4 9.7 7.2 0.1 6.0 5 1 1 6 6 5 0 Aromatic-di-Alanine (AdAR) repeat Fis1_TPR_C PF14853.1 ETN97930.1 - 0.84 9.5 26.4 0.44 10.4 1.3 4.5 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat Sda PF08970.5 ETN97930.1 - 1.3 8.6 4.9 40 3.8 0.1 4.0 4 1 0 4 4 4 0 Sporulation inhibitor A UVR PF02151.14 ETN97930.1 - 6.1 6.4 7.5 23 4.6 0.0 3.9 4 0 0 4 4 4 0 UvrB/uvrC motif Mob_Pre PF01076.14 ETN97930.1 - 6.7 6.2 12.2 3.6 7.1 0.7 2.8 1 1 2 3 3 3 0 Plasmid recombination enzyme HEAT_2 PF13646.1 ETN97931.1 - 0.0052 17.0 0.0 0.056 13.7 0.0 1.9 1 1 0 1 1 1 1 HEAT repeats HEAT PF02985.17 ETN97931.1 - 0.007 16.3 0.0 0.77 9.9 0.0 2.5 2 0 0 2 2 2 1 HEAT repeat CLASP_N PF12348.3 ETN97931.1 - 0.016 14.5 0.1 0.018 14.3 0.1 1.1 1 0 0 1 1 1 0 CLASP N terminal Retrotrans_gag PF03732.12 ETN97931.1 - 0.13 12.3 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Retrotransposon gag protein zf-C3HC4_2 PF13923.1 ETN97933.1 - 0.0024 17.8 3.1 0.038 14.0 2.2 2.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Tet_JBP PF12851.2 ETN97933.1 - 0.25 10.6 2.2 0.26 10.5 0.9 1.4 1 1 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily NAD_binding_7 PF13241.1 ETN97933.1 - 0.5 10.6 3.4 1.8 8.8 0.4 2.1 1 1 1 2 2 2 0 Putative NAD(P)-binding Cys_knot PF00007.17 ETN97933.1 - 2.4 8.2 12.6 0.2 11.7 4.2 2.1 1 1 1 2 2 2 0 Cystine-knot domain zf-CCHC PF00098.18 ETN97935.1 - 0.00026 20.7 9.3 0.00048 19.9 4.4 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.1 ETN97935.1 - 0.17 11.5 2.5 0.51 10.0 1.7 1.9 1 0 0 1 1 1 0 Zinc knuckle Exo_endo_phos_2 PF14529.1 ETN97936.1 - 2e-06 27.4 0.4 2e-06 27.4 0.3 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase DUF2972 PF11186.3 ETN97937.1 - 0.053 13.4 1.7 0.068 13.0 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) TPR_12 PF13424.1 ETN97938.1 - 7.5e-69 227.6 20.1 4.6e-15 55.3 0.8 6.0 3 3 3 6 6 6 6 Tetratricopeptide repeat TPR_11 PF13414.1 ETN97938.1 - 4.7e-35 119.0 20.1 2.5e-11 43.0 0.1 6.1 5 1 0 6 6 6 4 TPR repeat TPR_10 PF13374.1 ETN97938.1 - 4.3e-30 102.7 0.0 7.9e-08 31.9 0.0 8.2 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.1 ETN97938.1 - 1.3e-28 96.4 12.4 1.2e-05 24.6 0.0 8.7 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETN97938.1 - 1.3e-27 94.2 38.4 4.4e-07 29.2 0.8 9.9 9 1 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.12 ETN97938.1 - 2.3e-26 89.5 32.1 0.0013 18.4 0.0 9.5 9 1 0 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETN97938.1 - 1.2e-25 87.2 38.6 4.8e-05 22.8 0.1 9.1 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_17 PF13431.1 ETN97938.1 - 6.4e-12 44.6 8.1 0.34 11.2 0.9 7.6 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETN97938.1 - 8.8e-12 44.5 0.0 5.3 7.9 0.0 7.7 6 2 2 8 8 8 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETN97938.1 - 2.4e-11 43.9 0.1 0.021 15.5 0.0 5.2 2 1 4 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETN97938.1 - 5.7e-10 38.9 4.9 1.7 9.3 0.0 7.7 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETN97938.1 - 9.5e-08 32.2 0.7 3.4 8.0 0.0 5.1 3 2 2 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 ETN97938.1 - 3.9e-07 30.1 18.1 0.058 13.5 2.2 4.9 4 2 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 ETN97938.1 - 4.3e-05 22.6 7.9 3.4 6.9 0.0 7.1 9 0 0 9 9 9 1 SHNi-TPR DUF2225 PF09986.4 ETN97938.1 - 0.00033 20.2 14.2 0.022 14.2 0.6 4.0 1 1 1 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.13 ETN97938.1 - 0.0061 16.4 16.9 3.7 7.4 0.1 7.2 8 0 0 8 8 8 1 MIT (microtubule interacting and transport) domain Sel1 PF08238.7 ETN97938.1 - 0.018 15.6 13.6 2.2 9.0 0.2 6.1 6 0 0 6 6 6 0 Sel1 repeat TPR_21 PF09976.4 ETN97938.1 - 0.057 13.3 0.4 0.51 10.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TOM20_plant PF06552.7 ETN97938.1 - 0.091 12.3 2.7 4.4 6.8 0.1 3.2 2 1 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 Mob_Pre PF01076.14 ETN97938.1 - 0.12 11.9 8.4 0.79 9.3 0.4 3.4 3 1 1 4 4 4 0 Plasmid recombination enzyme DUF3889 PF13028.1 ETN97938.1 - 0.19 11.4 2.9 11 5.7 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3889) Methyltransf_3 PF01596.12 ETN97938.1 - 1.1 8.2 6.3 4 6.4 0.1 2.7 3 0 0 3 3 3 0 O-methyltransferase Sec5 PF15469.1 ETN97938.1 - 2.8 7.6 17.6 2.6 7.7 0.2 5.1 2 2 1 4 4 4 0 Exocyst complex component Sec5 Ribosomal_S3Ae PF01015.13 ETN97939.1 - 0.035 13.4 0.1 0.038 13.3 0.1 1.1 1 0 0 1 1 1 0 Ribosomal S3Ae family Phosphodiest PF01663.17 ETN97940.1 - 6.8e-29 101.3 0.1 8e-29 101.0 0.1 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 ETN97940.1 - 3.3e-06 26.6 0.0 4.6e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 ETN97940.1 - 0.0056 15.9 0.2 0.011 14.9 0.1 1.5 1 1 0 1 1 1 1 Sulfatase DUF229 PF02995.12 ETN97940.1 - 0.073 11.4 0.0 0.089 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Phosphodiest PF01663.17 ETN97941.1 - 6.8e-29 101.3 0.1 8e-29 101.0 0.1 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 ETN97941.1 - 3.3e-06 26.6 0.0 4.6e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 ETN97941.1 - 0.0056 15.9 0.2 0.011 14.9 0.1 1.5 1 1 0 1 1 1 1 Sulfatase DUF229 PF02995.12 ETN97941.1 - 0.073 11.4 0.0 0.089 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Nitroreductase PF00881.19 ETN97942.1 - 0.0021 17.8 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family SICA_beta PF12878.2 ETN97942.1 - 0.016 14.9 0.2 0.021 14.6 0.1 1.2 1 0 0 1 1 1 0 SICA extracellular beta domain DUF2247 PF10004.4 ETN97942.1 - 0.019 14.7 0.6 0.027 14.1 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) FliS PF02561.9 ETN97942.1 - 0.07 12.9 1.9 0.11 12.2 1.3 1.3 1 0 0 1 1 1 0 Flagellar protein FliS Symplekin_C PF12295.3 ETN97942.1 - 0.079 12.8 0.2 0.11 12.4 0.2 1.1 1 0 0 1 1 1 0 Symplekin tight junction protein C terminal Prp18 PF02840.10 ETN97942.1 - 0.14 12.0 1.9 0.39 10.5 0.8 1.8 1 1 1 2 2 2 0 Prp18 domain tRNA-Thr_ED PF08915.6 ETN97942.1 - 0.14 12.1 1.5 0.25 11.2 0.8 1.6 2 0 0 2 2 2 0 Archaea-specific editing domain of threonyl-tRNA synthetase dDENN PF03455.14 ETN97943.1 - 9.6e-11 41.5 0.6 2.2e-10 40.4 0.4 1.7 1 0 0 1 1 1 1 dDENN domain PPR_2 PF13041.1 ETN97943.1 - 5.2e-06 26.3 0.0 6.9e-05 22.7 0.0 2.5 2 0 0 2 2 2 1 PPR repeat family DUF3584 PF12128.3 ETN97945.1 - 0.0096 13.3 27.6 0.013 12.9 19.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF1664 PF07889.7 ETN97945.1 - 0.21 11.3 20.7 0.034 13.9 6.6 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Phage_GP20 PF06810.6 ETN97945.1 - 1.3 8.3 40.4 8 5.8 0.8 3.8 2 1 1 3 3 3 0 Phage minor structural protein GP20 bZIP_1 PF00170.16 ETN97945.1 - 5 7.1 16.4 1.9 8.4 0.9 3.9 2 1 1 3 3 3 0 bZIP transcription factor Pox_A_type_inc PF04508.7 ETN97945.1 - 7.9 6.5 6.2 3.8 7.5 0.1 3.4 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Peptidase_M15_3 PF08291.6 ETN97946.1 - 5.8e-17 61.4 0.0 1.4e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase M15 DUF912 PF06024.7 ETN97946.1 - 0.00012 22.0 0.8 0.0002 21.3 0.5 1.3 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Plasmodium_Vir PF05795.6 ETN97946.1 - 0.00031 20.0 0.1 0.00042 19.6 0.1 1.2 1 0 0 1 1 1 1 Plasmodium vivax Vir protein TMEM154 PF15102.1 ETN97946.1 - 0.00043 20.0 0.9 0.00066 19.4 0.6 1.2 1 0 0 1 1 1 1 TMEM154 protein family CD34_antigen PF06365.7 ETN97946.1 - 0.0017 18.0 0.1 0.0025 17.5 0.1 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family DUF2370 PF10176.4 ETN97946.1 - 0.0028 17.0 0.2 0.0039 16.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Baculo_E56 PF04639.7 ETN97946.1 - 0.0035 16.0 0.2 0.006 15.2 0.1 1.3 1 0 0 1 1 1 1 Baculoviral E56 protein, specific to ODV envelope Rifin_STEVOR PF02009.11 ETN97946.1 - 0.0054 16.4 0.1 0.0076 15.9 0.1 1.2 1 0 0 1 1 1 1 Rifin/stevor family DUF4448 PF14610.1 ETN97946.1 - 0.0079 15.7 0.0 0.0099 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Lamp PF01299.12 ETN97946.1 - 0.01 15.0 2.8 0.01 15.0 1.9 1.7 1 1 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) DUF2520 PF10728.4 ETN97946.1 - 0.024 14.0 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) Protocadherin PF08374.6 ETN97946.1 - 0.033 13.8 0.1 0.063 12.9 0.1 1.5 1 0 0 1 1 1 0 Protocadherin DAG1 PF05454.6 ETN97946.1 - 0.042 13.0 0.0 0.059 12.5 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Peptidase_M56 PF05569.6 ETN97946.1 - 0.055 12.4 0.1 0.073 12.0 0.1 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 Chordopox_A13L PF05961.6 ETN97946.1 - 0.083 12.8 0.5 0.083 12.8 0.4 1.9 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Peptidase_M15_2 PF05951.8 ETN97946.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) DUF1180 PF06679.7 ETN97946.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Glycophorin_A PF01102.13 ETN97946.1 - 0.19 11.4 3.9 0.49 10.1 2.7 1.8 1 1 0 1 1 1 0 Glycophorin A DUF3827 PF12877.2 ETN97946.1 - 0.29 9.1 4.5 0.14 10.2 1.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3827) Staphylokinase PF02821.11 ETN97947.1 - 0.07 12.9 1.9 0.1 12.4 1.3 1.2 1 0 0 1 1 1 0 Staphylokinase/Streptokinase family Sigma70_ner PF04546.8 ETN97948.1 - 0.081 12.5 2.0 0.1 12.2 1.4 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.1 ETN97948.1 - 0.3 11.4 5.4 0.46 10.8 3.8 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_E10 PF04805.7 ETN97949.1 - 0.013 15.0 0.2 0.03 13.8 0.1 1.6 1 0 0 1 1 1 0 E10-like protein conserved region Pentapeptide PF00805.17 ETN97950.1 - 0.0006 18.9 0.0 0.0014 17.8 0.0 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETN97950.1 - 0.087 12.6 0.1 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) DUF4097 PF13349.1 ETN97950.1 - 0.19 11.2 4.6 0.32 10.5 0.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4097) Colicin_Pyocin PF01320.13 ETN97952.1 - 5.3e-06 26.1 13.0 29 4.6 0.0 9.5 1 1 14 15 15 15 1 Colicin immunity protein / pyocin immunity protein DUF1961 PF09224.6 ETN97952.1 - 4.1e-05 22.7 15.3 12 4.9 0.1 6.9 1 1 12 13 13 13 10 Domain of unknown function (DUF1961) DUF243 PF03103.12 ETN97952.1 - 0.012 15.7 22.7 9.3 6.4 0.8 5.7 1 1 5 6 6 6 0 Domain of unknown function (DUF243) Mtr2 PF10429.4 ETN97952.1 - 1.2 8.9 33.3 29 4.3 0.3 7.5 1 1 7 8 8 8 0 Nuclear pore RNA shuttling protein Mtr2 Peptidase_M22 PF00814.20 ETN97955.1 - 0.011 15.2 0.0 0.012 15.0 0.0 1.0 1 0 0 1 1 1 0 Glycoprotease family HJURP_mid PF12346.3 ETN97956.1 - 0.031 14.3 0.3 0.063 13.3 0.2 1.5 1 1 0 1 1 1 0 Holliday junction recognition protein-associated repeat Kelch_6 PF13964.1 ETN97957.1 - 0.049 13.8 1.6 0.15 12.2 0.1 2.5 3 0 0 3 3 3 0 Kelch motif Voldacs PF03517.8 ETN97959.1 - 1.5 8.6 6.1 1.8 8.3 4.2 1.1 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling Lin-8 PF03353.10 ETN97959.1 - 2 7.6 11.1 2.3 7.4 7.7 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SAPS PF04499.10 ETN97959.1 - 6.4 5.2 11.1 7.8 5.0 7.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DDHD PF02862.12 ETN97959.1 - 8.5 6.0 10.0 11 5.6 7.0 1.1 1 0 0 1 1 1 0 DDHD domain Sec20 PF03908.8 ETN97960.1 - 0.0028 17.3 3.1 0.0045 16.6 1.3 2.0 2 0 0 2 2 2 1 Sec20 MCPsignal PF00015.16 ETN97960.1 - 0.017 14.6 0.1 3.1 7.2 0.1 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CDC37_N PF03234.9 ETN97962.1 - 0.0044 17.3 9.9 0.0049 17.2 5.7 1.8 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding Folliculin PF11704.3 ETN97962.1 - 0.85 9.1 9.2 2.4 7.7 0.0 2.4 2 1 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Allexi_40kDa PF05549.6 ETN97962.1 - 1.3 8.2 4.5 2.5 7.3 2.3 1.9 2 0 0 2 2 2 0 Allexivirus 40kDa protein TPR_12 PF13424.1 ETN97963.1 - 2.2e-85 280.6 11.4 1.2e-24 86.0 0.3 3.1 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETN97963.1 - 2.5e-48 161.5 23.9 3.4e-15 55.4 1.2 3.3 1 1 3 4 4 4 4 TPR repeat TPR_7 PF13176.1 ETN97963.1 - 3e-40 132.8 2.4 1.3e-08 33.9 0.0 5.1 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.23 ETN97963.1 - 1.5e-38 128.8 23.2 1.7e-09 36.8 1.8 5.1 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETN97963.1 - 2.1e-38 129.1 0.0 1.1e-07 31.5 0.1 5.0 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETN97963.1 - 2.1e-28 95.9 14.2 6.9e-07 28.7 0.1 5.2 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.1 ETN97963.1 - 1.1e-24 84.2 30.3 3.8e-06 26.2 1.5 5.1 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_17 PF13431.1 ETN97963.1 - 1.6e-15 55.9 7.9 0.00034 20.5 0.1 5.4 4 2 1 5 5 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETN97963.1 - 1.7e-11 43.6 0.0 0.086 13.5 0.0 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 ETN97963.1 - 4.6e-11 42.6 8.1 0.0002 21.4 0.4 3.6 1 1 3 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 ETN97963.1 - 1.1e-10 41.9 0.0 0.0016 19.0 0.0 3.6 1 1 2 4 4 4 4 Tetratricopeptide repeat RPN7 PF10602.4 ETN97963.1 - 1.1e-06 28.1 8.5 0.003 16.9 0.4 4.1 1 1 2 3 3 3 3 26S proteasome subunit RPN7 TPR_6 PF13174.1 ETN97963.1 - 1.5e-06 28.2 0.9 0.076 13.5 0.0 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat Ten1_2 PF15490.1 ETN97963.1 - 5.4e-06 25.9 0.1 1.7 8.2 0.0 3.9 1 1 3 4 4 4 2 Telomere-capping, CST complex subunit DUF357 PF04010.8 ETN97963.1 - 7.4e-06 25.5 8.0 0.28 10.8 0.1 4.1 1 1 3 4 4 4 2 Protein of unknown function (DUF357) TPR_3 PF07720.7 ETN97963.1 - 9.2e-06 25.3 9.8 0.0066 16.2 0.3 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETN97963.1 - 1e-05 25.7 0.8 0.029 14.7 0.1 3.6 1 1 3 4 4 4 2 Tetratricopeptide repeat Musclin PF11037.3 ETN97963.1 - 4.1e-05 23.2 0.0 7.6 6.1 0.0 4.5 4 1 1 5 5 5 0 Insulin-resistance promoting peptide in skeletal muscle SHNi-TPR PF10516.4 ETN97963.1 - 0.00011 21.3 0.2 0.76 9.0 0.0 4.5 5 0 0 5 5 5 1 SHNi-TPR PPR PF01535.15 ETN97963.1 - 0.0002 21.0 9.4 1.7 8.7 0.1 4.5 5 0 0 5 5 4 2 PPR repeat DUF627 PF04781.7 ETN97963.1 - 0.00025 20.6 4.9 2.3 7.8 0.1 3.9 2 2 2 4 4 4 2 Protein of unknown function (DUF627) MIT PF04212.13 ETN97963.1 - 0.00033 20.4 13.9 0.79 9.6 0.2 4.8 4 1 0 4 4 4 1 MIT (microtubule interacting and transport) domain ATP-synt_E_2 PF08112.6 ETN97963.1 - 0.00099 19.1 9.9 23 5.1 0.0 5.3 5 0 0 5 5 5 0 ATP synthase epsilon subunit Mob_Pre PF01076.14 ETN97963.1 - 0.0016 18.0 2.4 0.01 15.4 0.3 2.5 1 1 2 3 3 3 2 Plasmid recombination enzyme TPR_5 PF12688.2 ETN97963.1 - 0.004 17.1 0.1 2.7 8.0 0.0 3.6 2 1 2 4 4 4 1 Tetratrico peptide repeat DUF2977 PF11192.3 ETN97963.1 - 0.0053 16.5 0.1 67 3.4 0.0 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2977) Fis1_TPR_C PF14853.1 ETN97963.1 - 0.0064 16.3 11.7 0.77 9.6 0.2 4.2 5 0 0 5 5 4 1 Fis1 C-terminal tetratricopeptide repeat Aldo_ket_red PF00248.16 ETN97963.1 - 0.013 14.3 3.7 0.18 10.5 0.4 2.2 1 1 1 2 2 2 0 Aldo/keto reductase family Sel1 PF08238.7 ETN97963.1 - 0.026 15.1 7.1 22 5.8 0.1 4.8 5 0 0 5 5 5 0 Sel1 repeat Sipho_tail PF05709.6 ETN97963.1 - 0.064 12.3 0.5 0.76 8.8 0.0 2.2 1 1 0 2 2 2 0 Phage tail protein Clathrin PF00637.15 ETN97963.1 - 0.26 10.8 7.9 4.8 6.7 0.0 3.4 1 1 3 4 4 4 0 Region in Clathrin and VPS Membrane_bind PF14564.1 ETN97963.1 - 0.64 10.2 6.3 2.2 8.4 0.2 3.0 1 1 1 2 2 2 0 Membrane binding DUF244 PF03112.9 ETN97963.1 - 0.94 9.0 6.9 1.1 8.8 0.1 2.6 2 1 0 2 2 2 0 Uncharacterized protein family (ORF7) DUF SPOB_a PF14689.1 ETN97963.1 - 1.9 8.1 4.5 2.8 7.5 0.1 3.0 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_12 PF13424.1 ETN97964.1 - 2.2e-96 315.8 19.2 2.2e-26 91.5 0.3 4.7 1 1 3 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.1 ETN97964.1 - 3.6e-58 188.8 7.9 3.5e-09 35.7 0.0 7.1 6 1 1 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.23 ETN97964.1 - 2.3e-56 185.1 32.7 1.2e-10 40.5 0.9 7.1 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_11 PF13414.1 ETN97964.1 - 4.2e-55 183.2 35.6 7.4e-15 54.3 0.7 5.3 2 2 4 6 6 6 6 TPR repeat TPR_10 PF13374.1 ETN97964.1 - 2.2e-50 167.2 0.0 8.1e-09 35.1 0.0 7.0 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 ETN97964.1 - 1.2e-42 140.4 20.8 7.2e-08 31.7 0.3 7.1 6 1 1 7 7 7 7 Tetratricopeptide repeat TPR_8 PF13181.1 ETN97964.1 - 3.4e-37 123.4 43.3 4.4e-08 32.3 2.1 7.1 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_16 PF13432.1 ETN97964.1 - 4.4e-21 75.0 0.0 0.00017 22.1 0.0 4.5 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETN97964.1 - 1.3e-19 68.6 12.3 0.00018 21.4 0.1 7.6 6 4 1 8 8 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETN97964.1 - 1.5e-19 68.6 0.0 0.021 15.4 0.0 7.0 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.1 ETN97964.1 - 7.6e-14 51.1 5.1 0.04 14.3 0.0 6.7 7 0 0 7 7 6 3 Tetratricopeptide repeat Apc3 PF12895.2 ETN97964.1 - 6.2e-12 45.4 15.7 0.00015 21.7 0.5 5.1 1 1 5 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.1 ETN97964.1 - 2.4e-11 43.2 6.4 7.5e-05 22.0 0.0 3.6 1 1 2 3 3 3 3 Soluble NSF attachment protein, SNAP TPR_19 PF14559.1 ETN97964.1 - 7.2e-11 42.2 3.2 0.03 14.6 0.0 4.7 2 1 4 6 6 6 5 Tetratricopeptide repeat MIT PF04212.13 ETN97964.1 - 9.9e-10 38.1 26.1 0.025 14.4 0.3 6.9 4 2 3 7 7 7 4 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.4 ETN97964.1 - 2.1e-08 33.2 3.1 1.5 8.1 0.0 6.2 7 0 0 7 7 7 2 SHNi-TPR PPR PF01535.15 ETN97964.1 - 5.4e-08 32.2 15.4 0.041 13.8 0.1 6.4 7 0 0 7 7 6 2 PPR repeat Mob_Pre PF01076.14 ETN97964.1 - 5.2e-07 29.4 4.5 0.017 14.8 0.0 3.1 1 1 2 3 3 3 3 Plasmid recombination enzyme TPR_3 PF07720.7 ETN97964.1 - 1e-06 28.3 19.2 0.37 10.6 0.4 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat RPN7 PF10602.4 ETN97964.1 - 4.7e-06 26.0 17.1 0.055 12.8 0.4 5.5 1 1 4 5 5 5 2 26S proteasome subunit RPN7 Musclin PF11037.3 ETN97964.1 - 1e-05 25.1 0.0 3.5 7.2 0.0 5.3 6 1 1 7 7 7 1 Insulin-resistance promoting peptide in skeletal muscle DUF3568 PF12092.3 ETN97964.1 - 1.4e-05 24.8 8.4 0.016 14.9 0.1 5.4 2 2 4 6 6 6 1 Protein of unknown function (DUF3568) DUF3856 PF12968.2 ETN97964.1 - 4.3e-05 23.3 0.5 1.2 8.8 0.0 3.9 1 1 2 3 3 3 1 Domain of Unknown Function (DUF3856) ATP-synt_E_2 PF08112.6 ETN97964.1 - 4.4e-05 23.4 21.2 0.52 10.4 0.1 7.3 6 1 0 7 7 7 1 ATP synthase epsilon subunit TPR_5 PF12688.2 ETN97964.1 - 0.00014 21.8 0.2 1.4 8.9 0.0 4.6 1 1 4 6 6 6 1 Tetratrico peptide repeat Fis1_TPR_C PF14853.1 ETN97964.1 - 0.00016 21.4 18.8 2.9 7.8 0.1 6.1 7 0 0 7 7 6 2 Fis1 C-terminal tetratricopeptide repeat DUF357 PF04010.8 ETN97964.1 - 0.00019 21.0 11.1 0.72 9.5 0.2 5.1 1 1 4 5 5 5 1 Protein of unknown function (DUF357) DUF2225 PF09986.4 ETN97964.1 - 0.00045 19.7 10.9 0.075 12.4 0.3 3.0 1 1 2 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) Sel1 PF08238.7 ETN97964.1 - 0.00071 20.1 15.0 0.45 11.2 0.2 6.6 6 1 1 7 7 7 1 Sel1 repeat DUF627 PF04781.7 ETN97964.1 - 0.00097 18.7 8.3 0.91 9.1 0.0 4.9 3 2 1 4 4 4 1 Protein of unknown function (DUF627) mRNA_cap_C PF03919.10 ETN97964.1 - 0.0025 18.1 0.3 14 6.0 0.0 4.8 3 3 1 5 5 5 0 mRNA capping enzyme, C-terminal domain Clathrin PF00637.15 ETN97964.1 - 0.019 14.5 10.8 0.47 10.0 0.5 5.0 3 2 2 5 5 5 0 Region in Clathrin and VPS SHD1 PF03983.7 ETN97964.1 - 0.025 14.1 3.4 59 3.4 0.0 4.6 5 0 0 5 5 5 0 SLA1 homology domain 1, SHD1 Dynactin PF12455.3 ETN97964.1 - 0.13 11.1 0.2 0.92 8.3 0.0 2.4 3 1 1 4 4 3 0 Dynein associated protein DUF1449 PF07290.6 ETN97964.1 - 0.18 11.1 0.7 17 4.7 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1449) bPH_3 PF14470.1 ETN97964.1 - 0.69 10.2 9.1 13 6.1 0.1 3.7 2 1 2 4 4 4 0 Bacterial PH domain SLT PF01464.15 ETN97964.1 - 3.6 7.0 6.8 10 5.6 0.2 3.1 1 1 3 4 4 4 0 Transglycosylase SLT domain PPR_2 PF13041.1 ETN97964.1 - 4.3 7.4 7.7 7.5 6.6 0.1 3.9 5 0 0 5 5 3 0 PPR repeat family Vfa1 PF08432.5 ETN97965.1 - 0.062 13.3 12.6 0.077 13.0 8.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Trypan_PARP PF05887.6 ETN97965.1 - 0.18 11.6 2.5 0.21 11.4 1.7 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Sec62 PF03839.11 ETN97965.1 - 0.98 8.7 6.9 1.6 8.1 4.8 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 GOLD_2 PF13897.1 ETN97965.1 - 1.6 8.9 7.1 0.23 11.6 2.4 1.4 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Atrophin-1 PF03154.10 ETN97965.1 - 2.1 6.4 8.7 2.5 6.1 6.0 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF3987 PF13148.1 ETN97965.1 - 2.7 6.4 6.7 3.5 6.1 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) rve PF00665.21 ETN97966.1 - 8.8e-08 32.2 0.0 1.3e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 ETN97966.1 - 9.9e-06 24.9 0.0 1.7e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain TMEM171 PF15471.1 ETN97966.1 - 0.13 10.9 0.4 0.24 10.1 0.3 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 BACK PF07707.10 ETN97967.1 - 0.00015 21.5 0.0 0.00024 20.8 0.0 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch WD40 PF00400.27 ETN97968.1 - 6.1e-34 114.6 11.9 1.9e-12 46.5 0.7 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN97968.1 - 2.9e-06 25.7 1.0 0.00017 19.9 0.1 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETN97968.1 - 0.015 14.5 2.6 0.047 13.0 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4221) DUF2671 PF10877.3 ETN97968.1 - 0.04 13.7 0.9 0.069 12.9 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2671) Thermopsin PF05317.6 ETN97968.1 - 0.041 12.7 2.0 0.052 12.4 1.4 1.2 1 0 0 1 1 1 0 Thermopsin RyR PF02026.11 ETN97969.1 - 1e-05 25.4 0.9 3e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 RyR domain Fucose_iso_N2 PF07882.7 ETN97969.1 - 0.059 13.0 0.4 0.09 12.4 0.3 1.3 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain DUF3963 PF13124.1 ETN97970.1 - 0.029 14.1 0.8 0.069 12.9 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) Salp15 PF12115.3 ETN97970.1 - 0.051 13.7 0.4 0.11 12.6 0.1 1.6 2 0 0 2 2 2 0 Salivary protein of 15kDa inhibits CD4+ T cell activation Cas_Cas4 PF01930.12 ETN97970.1 - 0.069 13.0 2.7 0.15 11.9 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF83 FYVE_2 PF02318.11 ETN97970.1 - 1.2 9.0 5.5 3.1 7.7 0.2 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger PUB PF09409.5 ETN97971.1 - 0.0034 17.1 0.4 0.021 14.5 0.3 2.0 1 1 0 1 1 1 1 PUB domain Red1 PF07964.6 ETN97971.1 - 0.77 7.8 3.0 0.85 7.6 2.1 1.0 1 0 0 1 1 1 0 Rec10 / Red1 Kelch_2 PF07646.10 ETN97972.1 - 0.002 17.8 0.3 2.9 7.7 0.1 2.7 1 1 1 2 2 2 2 Kelch motif Methyltransf_FA PF12248.3 ETN97972.1 - 0.033 14.2 0.7 7 6.7 0.0 2.4 2 1 1 3 3 3 0 Farnesoic acid 0-methyl transferase Kelch_4 PF13418.1 ETN97972.1 - 0.048 13.4 0.5 1.4 8.7 0.0 2.4 1 1 1 2 2 2 0 Galactose oxidase, central domain Kelch_1 PF01344.20 ETN97972.1 - 0.087 12.3 0.0 16 5.1 0.0 2.4 2 0 0 2 2 2 0 Kelch motif Kelch_5 PF13854.1 ETN97972.1 - 0.1 12.5 0.0 0.54 10.2 0.0 2.0 2 0 0 2 2 2 0 Kelch motif UDPG_MGDP_dh_C PF03720.10 ETN97973.1 - 0.06 13.5 0.1 0.17 12.0 0.0 1.7 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain DUF1322 PF07032.6 ETN97973.1 - 0.27 11.4 2.8 6.9 6.9 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1322) Cys_rich_VLP PF14194.1 ETN97975.1 - 1.1 9.0 6.7 0.38 10.5 0.6 2.5 3 0 0 3 3 3 0 Cysteine-rich VLP WD40 PF00400.27 ETN97976.1 - 7.1e-13 47.8 0.7 4.1e-12 45.4 0.7 1.9 2 0 0 2 2 2 1 WD domain, G-beta repeat Marek_SORF3 PF07153.6 ETN97976.1 - 0.037 12.7 0.1 0.042 12.5 0.1 1.0 1 0 0 1 1 1 0 Marek's disease-like virus SORF3 protein Pentapeptide PF00805.17 ETN97978.1 - 0.00031 19.8 0.6 0.00071 18.7 0.0 1.9 2 0 0 2 2 2 1 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 ETN97978.1 - 0.00046 20.0 0.1 0.00083 19.1 0.0 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.1 ETN97978.1 - 0.0011 18.7 2.9 0.0093 15.7 1.7 2.4 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) CotJA PF11007.3 ETN97978.1 - 0.15 11.7 1.9 12 5.6 0.2 3.0 2 1 0 2 2 2 0 Spore coat associated protein JA (CotJA) WD40 PF00400.27 ETN97979.1 - 1.2e-05 24.9 2.4 3.7e-05 23.4 0.3 2.6 3 0 0 3 3 3 1 WD domain, G-beta repeat Nup160 PF11715.3 ETN97979.1 - 0.065 11.3 0.0 0.065 11.3 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Adeno_E1B_55K PF01696.12 ETN97980.1 - 0.11 10.8 0.8 0.17 10.2 0.5 1.2 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen Mit_ribos_Mrp51 PF11709.3 ETN97980.1 - 0.73 8.9 5.3 0.87 8.7 3.7 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit Ret_tiss PF10044.4 ETN97980.1 - 1.5 9.4 7.4 6.3 7.4 0.6 3.1 1 1 2 3 3 3 0 Retinal tissue protein PrgU PF09627.5 ETN97981.1 - 0.0098 15.4 3.2 0.024 14.2 2.2 1.8 1 1 0 1 1 1 1 PrgU-like protein Tox-HNH-HHH PF15637.1 ETN97981.1 - 0.013 15.2 1.0 0.021 14.5 0.7 1.3 1 0 0 1 1 1 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif DUF1033 PF06279.6 ETN97981.1 - 0.015 15.1 2.5 0.028 14.2 1.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1033) PHR PF08005.7 ETN97981.1 - 0.039 14.1 0.3 0.052 13.7 0.2 1.2 1 0 0 1 1 1 0 PHR domain DUF3245 PF11595.3 ETN97981.1 - 0.062 13.5 4.6 0.092 13.0 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) PUB PF09409.5 ETN97982.1 - 0.0001 21.9 0.9 0.00044 19.9 0.6 1.9 1 1 0 1 1 1 1 PUB domain CW_binding_1 PF01473.15 ETN97982.1 - 0.12 12.5 2.4 0.25 11.5 1.6 1.6 1 0 0 1 1 1 0 Putative cell wall binding repeat WD40 PF00400.27 ETN97984.1 - 1.1e-59 196.3 12.3 2.2e-10 39.9 0.1 6.0 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETN97984.1 - 3.1e-08 32.2 3.2 0.0067 14.6 0.0 3.9 1 1 1 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.6 ETN97984.1 - 1.5e-07 31.3 0.2 0.0014 18.4 0.1 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 ETN97984.1 - 0.00079 18.9 0.0 0.0043 16.5 0.0 2.1 1 1 0 1 1 1 1 PQQ-like domain Nbas_N PF15492.1 ETN97984.1 - 0.00081 18.5 0.2 0.5 9.4 0.0 2.8 1 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 ETN97984.1 - 0.00089 17.6 0.1 0.0028 16.0 0.0 1.7 1 1 1 2 2 2 1 Cytochrome D1 heme domain NHL PF01436.16 ETN97984.1 - 0.0014 18.5 0.2 2 8.4 0.0 2.6 2 0 0 2 2 2 2 NHL repeat BBS2_Mid PF14783.1 ETN97984.1 - 0.0016 18.1 4.4 16 5.3 0.1 5.3 2 1 3 5 5 5 0 Ciliary BBSome complex subunit 2, middle region PD40 PF07676.7 ETN97984.1 - 0.0017 17.9 2.8 2.7 7.7 0.0 3.7 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.9 ETN97984.1 - 0.0027 16.5 1.3 0.0073 15.1 0.4 1.8 1 1 1 2 2 2 1 Coatomer WD associated region DUF1652 PF07865.6 ETN97984.1 - 0.0051 16.3 0.1 1.1 8.9 0.0 3.2 4 1 0 4 4 4 1 Protein of unknown function (DUF1652) PQQ PF01011.16 ETN97984.1 - 0.0069 15.8 0.0 5.4 6.7 0.0 3.7 4 0 0 4 4 4 1 PQQ enzyme repeat Hira PF07569.6 ETN97984.1 - 0.013 14.7 2.6 3.7 6.6 0.0 3.9 1 1 3 4 4 4 0 TUP1-like enhancer of split YopX PF09643.5 ETN97984.1 - 0.035 14.0 0.1 0.059 13.3 0.1 1.6 1 1 0 1 1 1 0 YopX protein DUF1900 PF08954.6 ETN97985.1 - 0.034 13.6 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1900) DUF4007 PF13182.1 ETN97985.1 - 0.048 12.4 0.1 0.05 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4007) 7TM_GPCR_Srv PF10323.4 ETN97986.1 - 0.031 13.3 1.8 0.04 13.0 1.3 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv YMF19 PF02326.10 ETN97986.1 - 0.27 11.8 4.9 0.37 11.3 3.4 1.2 1 0 0 1 1 1 0 Plant ATP synthase F0 WD40 PF00400.27 ETN97987.1 - 1.4e-78 256.2 21.1 4.1e-15 54.9 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat PQQ_2 PF13360.1 ETN97987.1 - 9.4e-11 41.6 1.3 3.5e-05 23.3 0.3 2.7 1 1 1 2 2 2 2 PQQ-like domain DUF1258 PF06869.7 ETN97987.1 - 2.2e-08 33.4 0.1 0.2 10.7 0.0 5.1 1 1 3 5 5 5 2 Protein of unknown function (DUF1258) Pentapeptide PF00805.17 ETN97987.1 - 1.3e-05 24.3 0.0 2.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Gmad1 PF10647.4 ETN97987.1 - 1.8e-05 24.2 1.4 0.00068 19.0 0.2 3.1 1 1 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain BBS2_Mid PF14783.1 ETN97987.1 - 2.5e-05 24.0 0.1 0.61 9.8 0.0 4.8 1 1 4 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Pentapeptide_4 PF13599.1 ETN97987.1 - 0.00011 21.8 1.5 0.0012 18.5 0.8 1.9 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Cytochrom_D1 PF02239.11 ETN97987.1 - 0.0002 19.8 1.6 0.016 13.5 0.1 2.9 1 1 1 3 3 3 1 Cytochrome D1 heme domain PD40 PF07676.7 ETN97987.1 - 0.00076 19.0 12.6 11 5.8 0.0 6.3 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Pentapeptide_3 PF13576.1 ETN97987.1 - 0.00081 19.2 0.4 0.0041 16.9 0.3 2.2 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) WXG100 PF06013.7 ETN97987.1 - 0.001 19.0 0.0 18 5.3 0.0 4.9 5 0 0 5 5 5 0 Proteins of 100 residues with WXG NYD-SP28_assoc PF14775.1 ETN97987.1 - 0.0037 16.9 0.0 6.2 6.6 0.0 4.6 5 0 0 5 5 5 1 Sperm tail C-terminal domain Germane PF10646.4 ETN97987.1 - 0.004 17.3 0.0 7.8 6.6 0.0 3.6 2 1 1 3 3 3 1 Sporulation and spore germination PQQ PF01011.16 ETN97987.1 - 0.049 13.1 0.2 80 3.0 0.0 4.5 5 0 0 5 5 5 0 PQQ enzyme repeat DUF1513 PF07433.6 ETN97987.1 - 0.071 11.9 0.1 2.2 7.1 0.0 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1513) WD40 PF00400.27 ETN97988.1 - 1.1e-86 281.8 14.9 1.8e-14 52.9 0.1 7.2 6 1 1 7 7 7 7 WD domain, G-beta repeat PQQ_2 PF13360.1 ETN97988.1 - 1.6e-12 47.4 7.4 7.1e-07 28.9 0.4 2.8 1 1 2 3 3 3 3 PQQ-like domain DUF1258 PF06869.7 ETN97988.1 - 1.9e-08 33.7 0.2 0.015 14.3 0.0 4.9 1 1 4 5 5 5 1 Protein of unknown function (DUF1258) Cytochrom_D1 PF02239.11 ETN97988.1 - 3.2e-07 29.0 0.5 0.0027 16.0 0.0 2.4 1 1 1 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.7 ETN97988.1 - 3.3e-07 29.8 13.9 17 5.1 0.0 7.6 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Gmad1 PF10647.4 ETN97988.1 - 1.1e-06 28.2 0.1 0.039 13.3 0.0 4.5 2 1 1 5 5 5 1 Lipoprotein LpqB beta-propeller domain Pentapeptide PF00805.17 ETN97988.1 - 1.3e-05 24.2 0.0 2.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETN97988.1 - 8.7e-05 22.2 1.2 0.0003 20.5 0.8 1.8 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) WXG100 PF06013.7 ETN97988.1 - 0.00079 19.3 0.0 19 5.3 0.0 4.5 5 0 0 5 5 5 0 Proteins of 100 residues with WXG Pentapeptide_3 PF13576.1 ETN97988.1 - 0.00093 19.0 0.5 0.0045 16.8 0.4 2.1 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Peptidase_C9 PF01707.11 ETN97988.1 - 0.0082 15.7 0.0 14 5.2 0.0 3.7 5 0 0 5 5 5 0 Peptidase family C9 PQQ PF01011.16 ETN97988.1 - 0.01 15.3 0.1 58 3.4 0.0 4.7 5 0 0 5 5 5 0 PQQ enzyme repeat Proteasome_A_N PF10584.4 ETN97988.1 - 0.014 14.7 22.0 37 3.7 0.0 8.9 12 0 0 12 12 12 0 Proteasome subunit A N-terminal signature Pectate_lyase22 PF14583.1 ETN97988.1 - 0.017 13.5 0.0 0.92 7.8 0.0 2.7 2 1 1 3 3 3 0 Oligogalacturonate lyase Rho_Binding PF08912.6 ETN97990.1 - 0.038 14.3 8.0 0.038 14.3 5.6 2.9 1 1 2 3 3 3 0 Rho Binding zf-HC5HC2H PF13771.1 ETN97990.1 - 0.092 12.8 0.6 0.15 12.2 0.4 1.3 1 0 0 1 1 1 0 PHD-like zinc-binding domain Syntaxin_2 PF14523.1 ETN97990.1 - 0.11 12.5 10.6 0.035 14.1 3.5 2.2 2 0 0 2 2 2 0 Syntaxin-like protein GLTSCR1 PF15249.1 ETN97990.1 - 0.15 12.1 3.8 0.33 11.0 1.9 1.8 1 1 1 2 2 2 0 Glioma tumor suppressor candidate region RmuC PF02646.11 ETN97990.1 - 0.18 10.5 6.6 0.068 11.9 2.9 1.5 2 0 0 2 2 2 0 RmuC family Phage_1_1 PF08200.6 ETN97990.1 - 0.94 9.7 0.0 0.94 9.7 0.0 2.9 3 0 0 3 3 3 0 Bacteriophage 1.1 Protein TPR_MLP1_2 PF07926.7 ETN97990.1 - 1.1 8.9 15.7 1.7 8.4 10.9 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein COG2 PF06148.6 ETN97990.1 - 1.1 9.0 6.7 0.36 10.7 1.5 2.1 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 OmpH PF03938.9 ETN97990.1 - 1.5 8.7 10.5 2.9 7.8 0.1 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF972 PF06156.8 ETN97990.1 - 1.7 9.0 12.1 2.1 8.7 0.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF948 PF06103.6 ETN97990.1 - 1.9 8.4 8.7 1.8 8.4 0.7 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) LOH1CR12 PF10158.4 ETN97990.1 - 2.2 8.0 6.1 2.9 7.7 3.5 1.7 1 1 0 1 1 1 0 Tumour suppressor protein EF-hand_4 PF12763.2 ETN97991.1 - 4.6e-08 32.7 0.0 1.1e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand YMF19 PF02326.10 ETN97991.1 - 0.14 12.7 1.8 0.29 11.7 0.3 2.1 2 0 0 2 2 2 0 Plant ATP synthase F0 TPR_12 PF13424.1 ETN97993.1 - 9.1e-11 41.5 0.2 2.9e-10 39.9 0.1 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETN97993.1 - 8.7e-08 31.6 0.8 1.6e-07 30.8 0.6 1.4 1 0 0 1 1 1 1 TPR repeat Pkinase PF00069.20 ETN97993.1 - 1.7e-07 30.6 0.8 7.8e-06 25.2 0.2 2.1 2 0 0 2 2 2 1 Protein kinase domain TPR_8 PF13181.1 ETN97993.1 - 6.7e-07 28.6 3.2 0.00064 19.3 0.5 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETN97993.1 - 9e-07 28.2 5.6 0.0021 17.5 1.7 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETN97993.1 - 2.1e-05 23.9 1.0 0.23 11.3 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETN97993.1 - 0.00017 21.3 1.6 0.28 11.1 0.2 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETN97993.1 - 0.0022 17.7 4.1 0.75 9.8 0.3 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETN97993.1 - 0.0091 16.3 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat APH PF01636.18 ETN97993.1 - 0.013 15.2 0.1 0.019 14.6 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 ETN97993.1 - 0.013 15.0 0.7 0.024 14.2 0.5 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase TPR_3 PF07720.7 ETN97993.1 - 0.044 13.5 0.7 2 8.3 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Tau95 PF09734.4 ETN97994.1 - 0.034 13.4 1.3 0.039 13.2 0.9 1.0 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit SR-25 PF10500.4 ETN97994.1 - 0.038 13.4 17.1 0.042 13.3 11.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2956 PF11169.3 ETN97994.1 - 0.066 13.1 13.3 0.08 12.9 9.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) PEX11 PF05648.9 ETN97994.1 - 0.17 11.1 3.7 0.19 10.9 2.6 1.3 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) GAGA_bind PF06217.7 ETN97994.1 - 0.94 9.3 7.3 0.95 9.3 5.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family BLVR PF06375.6 ETN97994.1 - 1.1 9.0 18.1 1.8 8.3 12.5 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) UPF0564 PF10595.4 ETN97994.1 - 5.2 5.8 18.8 15 4.3 11.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0564 DUF1168 PF06658.7 ETN97994.1 - 6 6.3 19.1 8.6 5.8 13.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Casc1 PF12366.3 ETN97994.1 - 8.2 5.8 9.7 11 5.4 6.7 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 OTCace_N PF02729.16 ETN97995.1 - 0.00062 19.4 2.8 0.001 18.6 2.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain IFT57 PF10498.4 ETN97995.1 - 0.0098 14.6 4.8 0.014 14.1 3.3 1.3 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Glyco_hydro_47 PF01532.15 ETN97997.1 - 7.2e-76 255.6 0.3 8.8e-76 255.3 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Gly_rich PF12810.2 ETN97998.1 - 6.3e-09 35.7 33.5 1.7e-08 34.4 23.2 1.6 1 1 0 1 1 1 1 Glycine rich protein Acyl_transf_3 PF01757.17 ETN97999.1 - 0.061 12.1 0.8 0.086 11.6 0.6 1.2 1 0 0 1 1 1 0 Acyltransferase family WD40 PF00400.27 ETN98000.1 - 2.4e-21 74.7 7.7 4.9e-12 45.2 0.1 3.8 4 1 0 4 4 4 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETN98000.1 - 0.035 12.8 0.5 11 4.6 0.0 2.8 2 1 1 3 3 3 0 Nup133 N terminal like Nup160 PF11715.3 ETN98000.1 - 0.038 12.1 0.2 4.2 5.3 0.0 2.5 1 1 2 3 3 3 0 Nucleoporin Nup120/160 WD40 PF00400.27 ETN98001.1 - 3.4e-23 80.5 4.2 2.6e-07 30.2 0.2 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN98001.1 - 0.0017 16.5 0.0 0.0021 16.2 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Flavodoxin_3 PF12641.2 ETN98002.1 - 0.033 13.6 0.9 0.056 12.8 0.1 1.6 1 1 0 2 2 2 0 Flavodoxin domain PsbX PF06596.6 ETN98002.1 - 0.55 9.9 3.0 1.4 8.6 2.1 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) DUF2435 PF10363.4 ETN98003.1 - 0.00057 19.7 0.5 0.0018 18.1 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) DUF4240 PF14024.1 ETN98003.1 - 0.065 13.0 0.5 6.3 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4240) DNA_primase_lrg PF04104.9 ETN98003.1 - 0.097 11.9 1.0 0.23 10.6 0.1 1.8 2 0 0 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit CIDE-N PF02017.10 ETN98003.1 - 0.23 11.2 4.5 10 5.9 0.0 3.2 3 0 0 3 3 3 0 CIDE-N domain Utp13 PF08625.6 ETN98003.1 - 0.29 10.7 4.7 2.6 7.6 0.3 2.9 1 1 2 3 3 3 0 Utp13 specific WD40 associated domain 7TMR-HDED PF07697.6 ETN98003.1 - 0.55 9.9 4.3 0.42 10.3 1.6 1.8 1 1 1 2 2 2 0 7TM-HD extracellular DUF573 PF04504.9 ETN98003.1 - 0.67 10.2 4.0 0.69 10.2 0.2 2.4 1 1 2 3 3 3 0 Protein of unknown function, DUF573 PUB PF09409.5 ETN98005.1 - 0.00053 19.6 0.2 0.0014 18.3 0.1 1.7 1 1 0 1 1 1 1 PUB domain Baculo_19 PF04798.7 ETN98005.1 - 0.07 12.5 0.9 0.082 12.2 0.6 1.3 1 1 0 1 1 1 0 Baculovirus 19 kDa protein conserved region MerR_1 PF13411.1 ETN98005.1 - 0.1 12.3 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 MerR HTH family regulatory protein CW_binding_1 PF01473.15 ETN98005.1 - 1.6 8.9 9.0 0.23 11.6 2.1 2.3 2 0 0 2 2 2 0 Putative cell wall binding repeat SMN PF06003.7 ETN98006.1 - 0.02 13.9 8.0 0.024 13.7 5.5 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Menin PF05053.8 ETN98006.1 - 0.087 10.9 6.1 0.093 10.8 4.2 1.0 1 0 0 1 1 1 0 Menin CENP-T PF15511.1 ETN98006.1 - 0.21 10.7 10.0 0.23 10.6 6.9 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Apt1 PF10351.4 ETN98006.1 - 0.56 8.9 12.6 0.53 9.0 8.7 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Daxx PF03344.10 ETN98006.1 - 0.57 8.6 22.8 0.55 8.6 15.8 1.0 1 0 0 1 1 1 0 Daxx Family Hid1 PF12722.2 ETN98006.1 - 0.65 7.6 9.7 0.67 7.5 6.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein YqfQ PF14181.1 ETN98006.1 - 1.8 8.5 11.9 2.2 8.2 8.2 1.1 1 0 0 1 1 1 0 YqfQ-like protein POX PF07526.6 ETN98006.1 - 3.4 7.8 5.7 4.2 7.5 3.9 1.3 1 0 0 1 1 1 0 Associated with HOX Tim54 PF11711.3 ETN98006.1 - 3.9 5.9 7.6 5 5.6 5.3 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Nop53 PF07767.6 ETN98006.1 - 4.9 6.0 19.8 5.9 5.7 13.7 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SAPS PF04499.10 ETN98006.1 - 5.2 5.5 10.9 5.3 5.5 7.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RP-C_C PF11800.3 ETN98006.1 - 6.5 6.3 7.0 7.3 6.2 4.8 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Nop14 PF04147.7 ETN98006.1 - 7.8 4.2 29.7 9.8 3.9 20.6 1.1 1 0 0 1 1 1 0 Nop14-like family SprA-related PF12118.3 ETN98007.1 - 0.0099 15.2 3.8 0.011 15.0 2.6 1.1 1 0 0 1 1 1 1 SprA-related family Vfa1 PF08432.5 ETN98007.1 - 0.015 15.3 14.1 0.021 14.8 9.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2201_N PF13203.1 ETN98007.1 - 0.049 12.8 4.2 0.065 12.4 2.9 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Pox_Ag35 PF03286.9 ETN98007.1 - 0.08 12.4 14.3 0.1 12.1 9.9 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DDHD PF02862.12 ETN98007.1 - 0.083 12.6 2.9 0.095 12.4 2.0 1.1 1 0 0 1 1 1 0 DDHD domain POX PF07526.6 ETN98007.1 - 1.1 9.5 7.9 1.6 8.9 5.5 1.3 1 0 0 1 1 1 0 Associated with HOX CDC45 PF02724.9 ETN98007.1 - 1.4 6.8 13.0 1.7 6.5 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Prog_receptor PF02161.10 ETN98007.1 - 2.6 6.7 4.9 3 6.5 3.4 1.1 1 0 0 1 1 1 0 Progesterone receptor NPR3 PF03666.8 ETN98007.1 - 5.5 5.4 12.3 0.85 8.0 5.6 1.6 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3078 PF11276.3 ETN98008.1 - 0.079 13.1 0.6 0.15 12.2 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3078) Motile_Sperm PF00635.21 ETN98009.1 - 0.062 12.9 0.1 0.082 12.5 0.1 1.2 1 0 0 1 1 1 0 MSP (Major sperm protein) domain Syja_N PF02383.13 ETN98011.1 - 0.015 14.1 5.2 0.041 12.6 2.0 2.5 1 1 2 3 3 3 0 SacI homology domain Cystatin PF00031.16 ETN98011.1 - 0.32 11.1 2.9 7.6 6.7 0.0 2.6 3 0 0 3 3 3 0 Cystatin domain WD40 PF00400.27 ETN98012.1 - 4.7e-17 61.1 5.3 1.1e-11 44.1 0.1 3.2 3 1 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETN98012.1 - 0.00015 20.0 0.2 0.093 10.8 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Rtf2 PF04641.7 ETN98013.1 - 1.1e-08 34.6 0.0 1.7e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 ETN98013.1 - 9.5e-05 21.8 0.1 0.034 13.6 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 ETN98013.1 - 0.0031 17.4 0.0 0.0078 16.1 0.0 1.6 1 1 0 1 1 1 1 U-box domain V-set_CD47 PF08204.6 ETN98013.1 - 0.11 12.2 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain zf-TRAF PF02176.13 ETN98014.1 - 0.0051 17.1 1.1 0.0051 17.1 0.7 2.3 3 0 0 3 3 3 1 TRAF-type zinc finger Tubulin PF00091.20 ETN98015.1 - 0.0011 18.8 0.3 0.0018 18.0 0.1 1.3 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FokI_N PF02981.10 ETN98015.1 - 0.037 13.6 0.2 0.059 12.9 0.2 1.4 1 0 0 1 1 1 0 Restriction endonuclease FokI, recognition domain DUF2645 PF10840.3 ETN98015.1 - 0.53 10.4 7.0 0.35 11.0 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2645) CAP_C PF08603.6 ETN98016.1 - 2.9e-20 72.2 1.2 4.5e-20 71.5 0.8 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal CAP_N PF01213.14 ETN98016.1 - 3e-08 33.3 0.6 3.6e-08 33.0 0.4 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal TBCC PF07986.7 ETN98016.1 - 4e-05 23.0 3.8 6e-05 22.4 2.6 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor C EF-hand_7 PF13499.1 ETN98017.1 - 1.6e-06 28.1 0.5 3.1e-06 27.2 0.4 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 ETN98017.1 - 0.00011 21.2 0.2 0.44 9.9 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 ETN98017.1 - 0.00045 19.8 0.1 1.1 9.3 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 ETN98017.1 - 0.017 14.7 0.3 0.12 12.0 0.1 2.2 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_10 PF14788.1 ETN98017.1 - 0.019 14.6 1.0 0.16 11.6 0.0 2.7 3 0 0 3 3 3 0 EF hand SLD3 PF08639.5 ETN98018.1 - 0.054 12.1 3.5 0.071 11.7 2.4 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 COX14 PF14880.1 ETN98018.1 - 0.19 11.3 2.4 0.74 9.4 0.0 2.3 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Peptidase_S49_N PF08496.5 ETN98018.1 - 2.7 7.7 4.8 3.8 7.2 3.4 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RGS-like PF09128.6 ETN98019.1 - 0.38 10.2 5.7 0.5 9.8 3.6 1.4 1 1 0 1 1 1 0 Regulator of G protein signalling-like domain Vps51 PF08700.6 ETN98019.1 - 0.55 10.0 6.3 7.8 6.4 0.3 2.8 1 1 2 3 3 3 0 Vps51/Vps67 Enkurin PF13864.1 ETN98019.1 - 1.4 9.1 9.0 4.3 7.5 2.0 2.6 1 1 1 2 2 2 0 Calmodulin-binding DUF3287 PF11690.3 ETN98019.1 - 1.6 8.8 6.0 2.5 8.2 1.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) DUF1940 PF09155.5 ETN98019.1 - 9.7 6.0 10.1 0.6 9.9 2.2 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF1940) PseudoU_synth_2 PF00849.17 ETN98020.1 - 0.0038 17.0 0.4 0.0038 17.0 0.3 1.6 2 0 0 2 2 2 1 RNA pseudouridylate synthase DUF2373 PF10180.4 ETN98020.1 - 3.8 7.1 6.0 14 5.3 4.1 2.0 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) PseudoU_synth_2 PF00849.17 ETN98021.1 - 1.3e-08 34.8 0.0 3.2e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 RNA pseudouridylate synthase Mod_r PF07200.8 ETN98021.1 - 0.045 13.6 1.2 0.13 12.2 0.8 1.7 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF1743 PF08489.6 ETN98022.1 - 0.0036 17.0 0.0 0.0054 16.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1743) 4HB_MCP_1 PF12729.2 ETN98023.1 - 0.0064 15.8 2.7 0.01 15.2 1.9 1.3 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction SLIDE PF09111.5 ETN98023.1 - 0.051 13.3 2.7 0.29 10.8 0.0 2.1 1 1 1 2 2 2 0 SLIDE CRAL_TRIO PF00650.15 ETN98024.1 - 0.046 13.2 0.6 0.073 12.5 0.3 1.5 1 1 1 2 2 2 0 CRAL/TRIO domain TPR_12 PF13424.1 ETN98025.1 - 6.2e-27 93.3 9.0 5.3e-18 64.7 0.6 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETN98025.1 - 8.3e-11 41.3 13.8 2.1e-05 24.0 2.9 3.3 2 1 1 3 3 3 3 TPR repeat TPR_7 PF13176.1 ETN98025.1 - 4.3e-10 38.6 4.2 0.011 15.4 0.0 4.8 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETN98025.1 - 5.5e-10 38.8 0.0 0.0038 17.1 0.0 3.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETN98025.1 - 4.2e-09 35.5 23.0 0.0019 17.8 0.7 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETN98025.1 - 5.1e-08 32.1 20.5 2.8e-05 23.5 0.2 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETN98025.1 - 2.4e-07 30.1 15.5 0.076 12.9 0.2 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETN98025.1 - 0.0035 17.6 3.9 4.1 8.0 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF2225 PF09986.4 ETN98025.1 - 0.0056 16.1 11.8 0.14 11.6 3.3 2.1 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.13 ETN98025.1 - 0.058 13.2 10.3 0.21 11.4 0.1 3.6 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_17 PF13431.1 ETN98025.1 - 0.17 12.1 5.6 5.4 7.4 0.0 4.1 4 2 1 5 5 5 0 Tetratricopeptide repeat Alginate_lyase2 PF08787.6 ETN98025.1 - 0.25 10.9 4.8 0.31 10.6 1.7 1.9 1 1 1 2 2 2 0 Alginate lyase Mob_Pre PF01076.14 ETN98025.1 - 8.6 5.9 8.8 16 5.0 0.1 2.2 1 1 1 2 2 2 0 Plasmid recombination enzyme Pkinase PF00069.20 ETN98026.1 - 1.5e-56 191.4 0.1 2.9e-56 190.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETN98026.1 - 1.5e-22 79.9 0.0 2.8e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETN98026.1 - 4.8e-06 25.7 0.0 1.4 7.7 0.0 3.2 2 1 1 3 3 3 3 Kinase-like DUF1798 PF08807.5 ETN98026.1 - 0.0088 15.7 2.6 0.02 14.5 1.8 1.6 1 0 0 1 1 1 1 Bacterial domain of unknown function (DUF1798) WD40 PF00400.27 ETN98027.1 - 6.8e-67 219.1 20.6 8.2e-12 44.5 0.6 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETN98027.1 - 2.1e-13 49.3 3.4 0.0018 16.5 0.1 5.8 3 1 2 6 6 6 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETN98027.1 - 0.002 16.9 13.0 0.058 12.1 0.1 4.2 1 1 1 3 3 3 1 Nup133 N terminal like DUF851 PF05867.6 ETN98027.1 - 0.0081 15.4 0.0 3.9 6.6 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF851) DUF911 PF06023.7 ETN98031.1 - 0.0096 15.1 0.2 0.012 14.7 0.2 1.2 1 0 0 1 1 1 1 Archaeal protein of unknown function (DUF911) SporV_AA PF12164.3 ETN98031.1 - 0.025 14.5 0.3 0.047 13.6 0.2 1.5 1 0 0 1 1 1 0 Stage V sporulation protein AA TFIIE_alpha PF02002.12 ETN98032.1 - 0.16 11.4 0.8 0.37 10.3 0.6 1.6 1 0 0 1 1 1 0 TFIIE alpha subunit HEAT_2 PF13646.1 ETN98033.1 - 0.0013 18.9 0.0 0.0023 18.1 0.0 1.6 1 1 0 1 1 1 1 HEAT repeats HEAT PF02985.17 ETN98033.1 - 0.0014 18.4 0.0 0.35 11.0 0.0 2.6 2 0 0 2 2 2 2 HEAT repeat TIP120 PF08623.5 ETN98033.1 - 0.029 13.9 0.0 3 7.3 0.0 2.0 1 1 1 2 2 2 0 TATA-binding protein interacting (TIP20) DUF1847 PF08901.6 ETN98035.1 - 0.1 12.0 1.4 0.14 11.6 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1847) DUF3137 PF11335.3 ETN98035.1 - 0.11 12.1 2.4 3 7.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3137) DRY_EERY PF09750.4 ETN98036.1 - 0.053 13.6 0.8 0.061 13.4 0.5 1.1 1 0 0 1 1 1 0 Alternative splicing regulator THDPS_N PF14790.1 ETN98036.1 - 0.061 12.9 0.0 0.089 12.4 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Thia_YuaJ PF09515.5 ETN98037.1 - 0.0029 17.3 0.6 0.34 10.6 0.1 2.2 2 0 0 2 2 2 2 Thiamine transporter protein (Thia_YuaJ) Neurensin PF14927.1 ETN98037.1 - 0.0091 15.3 0.0 0.022 14.1 0.0 1.6 1 0 0 1 1 1 1 Neurensin Mhr1 PF12829.2 ETN98037.1 - 0.15 11.8 0.8 0.29 10.9 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulation of mitochondrial recombination Peptidase_M56 PF05569.6 ETN98037.1 - 3.2 6.6 6.9 0.26 10.2 0.6 2.1 3 0 0 3 3 3 0 BlaR1 peptidase M56 DUF912 PF06024.7 ETN98037.1 - 4.4 7.4 7.8 2.9 7.9 0.3 3.4 3 1 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) MCM PF00493.18 ETN98041.1 - 3.3e-135 450.1 0.0 5.6e-135 449.3 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 ETN98041.1 - 1.3e-16 61.1 0.5 1.3e-16 61.1 0.4 2.5 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 ETN98041.1 - 4.9e-08 32.3 0.1 2.2e-05 23.7 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 ETN98041.1 - 3.3e-07 30.1 0.0 1.1e-06 28.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 ETN98041.1 - 0.0021 17.6 0.0 0.0064 16.0 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 ETN98041.1 - 0.0049 16.3 0.0 3 7.2 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 ETN98041.1 - 0.017 15.1 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.24 ETN98041.1 - 0.023 14.9 0.0 0.093 12.9 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RRM_6 PF14259.1 ETN98042.1 - 0.00073 19.4 0.0 0.0022 17.9 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETN98042.1 - 0.014 15.0 0.0 0.083 12.5 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETN98042.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA PF00004.24 ETN98043.1 - 0.00027 21.1 0.3 0.087 13.0 0.0 4.1 4 1 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.20 ETN98046.1 - 7.4e-27 94.1 4.1 1.6e-13 50.4 3.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETN98046.1 - 2.3e-12 46.5 0.7 1.8e-05 23.9 0.3 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase DUF1622 PF07784.6 ETN98046.1 - 0.039 13.6 0.0 0.11 12.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1622) APH PF01636.18 ETN98046.1 - 0.048 13.3 0.1 0.074 12.7 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family RDD PF06271.7 ETN98046.1 - 0.5 10.2 4.7 13 5.6 0.1 2.9 3 0 0 3 3 3 0 RDD family DUF912 PF06024.7 ETN98047.1 - 0.0032 17.4 1.4 0.0032 17.4 1.0 2.1 1 1 1 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) SID-1_RNA_chan PF13965.1 ETN98047.1 - 0.022 12.9 4.5 0.025 12.7 3.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Rot1 PF10681.4 ETN98047.1 - 1.3 8.3 6.5 0.13 11.6 0.8 1.8 2 0 0 2 2 2 0 Chaperone for protein-folding within the ER, fungal DSPc PF00782.15 ETN98048.1 - 4.6e-22 78.0 0.1 5.7e-22 77.7 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 ETN98048.1 - 0.00016 21.1 0.0 0.0002 20.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 ETN98048.1 - 0.0039 16.1 0.1 0.0042 16.0 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase3 PF13350.1 ETN98048.1 - 0.13 12.4 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family AA_permease PF00324.16 ETN98049.1 - 9.2e-15 53.9 18.3 1.5e-14 53.2 12.7 1.3 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETN98049.1 - 0.00012 20.7 19.2 0.00018 20.2 13.3 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETN98050.1 - 6.5e-17 61.0 11.6 6.7e-15 54.3 4.8 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 ETN98050.1 - 4e-09 35.5 14.1 1.9e-08 33.2 9.8 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETN98051.1 - 3.1e-08 32.4 1.3 3.9e-08 32.0 0.9 1.1 1 0 0 1 1 1 1 Amino acid permease Annexin PF00191.15 ETN98052.1 - 6.4e-06 25.9 0.0 8.6e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Annexin DUF1359 PF07097.6 ETN98053.1 - 0.019 15.0 1.4 0.019 15.0 1.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1359) HI0933_like PF03486.9 ETN98053.1 - 0.078 11.4 0.3 0.082 11.3 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein DNA_pol_B PF00136.16 ETN98053.1 - 0.14 10.8 1.7 0.14 10.9 1.2 1.1 1 0 0 1 1 1 0 DNA polymerase family B DUF2281 PF10047.4 ETN98053.1 - 1.6 9.0 5.0 2.8 8.2 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2281) Capsule_synth PF05159.9 ETN98057.1 - 0.063 12.7 1.2 0.076 12.4 0.8 1.1 1 0 0 1 1 1 0 Capsule polysaccharide biosynthesis protein DUF825 PF05695.7 ETN98057.1 - 0.1 9.9 4.5 0.12 9.7 3.2 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF825) DUF3552 PF12072.3 ETN98058.1 - 0.018 14.2 6.8 0.024 13.8 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) IncA PF04156.9 ETN98058.1 - 0.042 13.4 0.2 0.042 13.4 0.1 1.2 1 0 0 1 1 1 0 IncA protein UPF0449 PF15136.1 ETN98058.1 - 0.064 13.4 2.2 0.07 13.3 1.5 1.3 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 TPR_MLP1_2 PF07926.7 ETN98058.1 - 0.076 12.7 7.5 0.1 12.3 5.2 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Prefoldin PF02996.12 ETN98058.1 - 0.1 12.2 0.6 0.1 12.2 0.4 1.8 2 1 0 2 2 2 0 Prefoldin subunit DUF2681 PF10883.3 ETN98058.1 - 0.16 12.1 1.5 0.35 11.1 0.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) CCDC-167 PF15188.1 ETN98058.1 - 1.5 8.7 4.7 0.89 9.5 1.6 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF3584 PF12128.3 ETN98059.1 - 0.00016 19.2 3.7 0.00019 18.9 2.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) OmpH PF03938.9 ETN98059.1 - 0.098 12.5 5.9 0.12 12.3 4.1 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) IncA PF04156.9 ETN98059.1 - 2.3 7.7 9.6 3.3 7.2 6.7 1.3 1 1 0 1 1 1 0 IncA protein DUF913 PF06025.7 ETN98060.1 - 0.01 14.6 0.5 0.059 12.1 0.2 1.7 1 1 1 2 2 2 0 Domain of Unknown Function (DUF913) DUF1884 PF08967.5 ETN98060.1 - 0.029 14.4 0.0 0.068 13.2 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1884) PPR PF01535.15 ETN98061.1 - 4e-06 26.4 0.3 0.033 14.1 0.0 2.7 2 0 0 2 2 2 2 PPR repeat PPR_2 PF13041.1 ETN98061.1 - 5.5e-05 23.0 0.7 0.007 16.3 0.0 2.3 1 1 1 2 2 2 2 PPR repeat family DUF1900 PF08954.6 ETN98061.1 - 0.033 13.7 0.5 0.63 9.5 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1900) Nyv1_N PF09426.5 ETN98061.1 - 0.058 12.9 0.2 0.083 12.4 0.1 1.4 1 0 0 1 1 1 0 Vacuolar R-SNARE Nyv1 N terminal PPR_3 PF13812.1 ETN98061.1 - 0.088 13.1 0.0 25 5.4 0.0 2.6 2 0 0 2 2 2 0 Pentatricopeptide repeat domain DUF2672 PF10878.3 ETN98061.1 - 0.11 12.2 2.8 0.094 12.4 0.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2672) WD40 PF00400.27 ETN98062.1 - 4.5e-06 26.3 3.5 6.4e-06 25.8 0.5 2.2 2 1 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETN98062.1 - 0.031 12.4 0.0 0.031 12.4 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 HAD PF12710.2 ETN98062.1 - 0.11 12.6 0.0 0.12 12.5 0.0 1.0 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PAPA-1 PF04795.7 ETN98063.1 - 0.12 13.1 3.5 0.27 11.9 2.4 1.5 1 0 0 1 1 1 0 PAPA-1-like conserved region Pkinase PF00069.20 ETN98065.1 - 3.9e-12 45.8 4.0 1.3e-08 34.2 0.7 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETN98065.1 - 1.3e-06 27.6 2.7 7.9e-06 25.1 0.4 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase RhoGEF PF00621.15 ETN98066.1 - 3.5e-11 43.3 0.0 6.2e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain SQS_PSY PF00494.14 ETN98067.1 - 5.4e-06 25.9 0.0 7e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Arm PF00514.18 ETN98068.1 - 0.086 12.6 0.0 0.35 10.7 0.0 2.1 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 ETN98068.1 - 0.13 12.8 0.0 15 6.2 0.0 3.4 4 0 0 4 4 4 0 HEAT-like repeat HEAT PF02985.17 ETN98068.1 - 0.97 9.6 4.6 1.1 9.5 0.0 3.4 4 0 0 4 4 4 0 HEAT repeat Herpes_BBRF1 PF04793.7 ETN98069.1 - 0.011 14.4 1.2 0.015 14.1 0.8 1.1 1 0 0 1 1 1 0 BRRF1-like protein DUF3440 PF11922.3 ETN98069.1 - 0.031 13.8 0.2 0.036 13.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) NACHT PF05729.7 ETN98070.1 - 0.0034 17.0 0.7 0.011 15.4 0.1 1.8 2 0 0 2 2 2 1 NACHT domain XPA_N PF01286.13 ETN98070.1 - 0.034 13.8 0.0 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 XPA protein N-terminal DUF1056 PF06341.6 ETN98070.1 - 0.76 9.8 2.8 2.7 8.0 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1056) LAM_C PF12544.3 ETN98071.1 - 0.39 10.7 7.1 0.42 10.6 4.9 1.1 1 0 0 1 1 1 0 Lysine-2,3-aminomutase TEX19 PF15553.1 ETN98071.1 - 0.52 10.1 9.9 0.62 9.9 6.9 1.1 1 0 0 1 1 1 0 Testis-expressed protein 19 DUF2890 PF11081.3 ETN98071.1 - 1.9 8.5 14.6 2 8.4 10.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) alpha-hel2 PF14456.1 ETN98071.1 - 2.8 6.6 4.9 2.8 6.6 3.4 1.1 1 0 0 1 1 1 0 Alpha-helical domain 2 Trypan_PARP PF05887.6 ETN98071.1 - 4.7 7.0 12.9 5.4 6.8 8.9 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Nop14 PF04147.7 ETN98071.1 - 6.3 4.5 19.6 6.6 4.5 13.6 1.0 1 0 0 1 1 1 0 Nop14-like family Pex16 PF08610.5 ETN98071.1 - 7.4 5.4 8.5 8.1 5.3 5.9 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Pox_RNA_Pol_19 PF05320.7 ETN98071.1 - 7.7 6.2 13.9 9.6 5.9 9.6 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit WBS_methylT PF12589.3 ETN98071.1 - 8.2 6.9 16.2 12 6.4 11.2 1.3 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome RGS PF00615.14 ETN98073.1 - 0.0078 16.3 3.6 1.8 8.6 0.4 2.3 2 1 0 2 2 2 2 Regulator of G protein signaling domain Ribonuclease_3 PF00636.21 ETN98073.1 - 1.7 9.1 5.0 61 4.1 3.4 2.7 1 1 0 1 1 1 0 Ribonuclease III domain ATG2_CAD PF13329.1 ETN98074.1 - 0.11 12.0 3.3 0.24 10.9 2.3 1.6 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif Med15 PF09606.5 ETN98074.1 - 1 7.4 40.0 1.2 7.2 27.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 ETN98074.1 - 1.9 6.5 37.0 2.1 6.4 25.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4617 PF15395.1 ETN98074.1 - 7.9 4.3 37.7 9.8 4.0 26.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4617) SOBP PF15279.1 ETN98074.1 - 8.3 6.6 28.4 9.6 6.4 19.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DHC_N2 PF08393.8 ETN98075.1 - 8.9e-17 60.6 7.2 3.6e-16 58.6 5.0 2.0 1 1 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 RPAP3_C PF13877.1 ETN98076.1 - 0.015 15.2 0.5 0.029 14.3 0.2 1.6 1 1 1 2 2 2 0 Potential Monad-binding region of RPAP3 Pescadillo_N PF06732.6 ETN98076.1 - 0.039 13.2 1.4 0.046 12.9 0.9 1.0 1 0 0 1 1 1 0 Pescadillo N-terminus WD40 PF00400.27 ETN98079.1 - 9.5e-66 215.5 14.3 3.2e-13 49.0 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETN98079.1 - 6.7e-07 27.8 8.7 0.029 12.5 0.2 5.1 1 1 3 4 4 4 4 Nucleoporin Nup120/160 DUF1258 PF06869.7 ETN98079.1 - 8.8e-07 28.2 2.0 0.041 12.9 0.1 3.6 1 1 3 4 4 4 3 Protein of unknown function (DUF1258) Nucleoporin_N PF08801.6 ETN98079.1 - 1.5e-05 23.9 6.2 0.12 11.1 0.2 4.2 1 1 2 3 3 3 3 Nup133 N terminal like PQQ_2 PF13360.1 ETN98079.1 - 2.5e-05 23.8 0.7 0.03 13.7 0.1 2.2 1 1 1 2 2 2 2 PQQ-like domain Cytochrom_D1 PF02239.11 ETN98079.1 - 0.0012 17.2 1.0 1.2 7.3 0.0 2.9 1 1 2 3 3 3 2 Cytochrome D1 heme domain HARP PF07443.8 ETN98079.1 - 0.0057 16.0 0.1 9.4 5.7 0.0 3.5 3 0 0 3 3 3 1 HepA-related protein (HARP) PD40 PF07676.7 ETN98079.1 - 0.011 15.3 4.2 2.1 8.1 0.1 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 ETN98079.1 - 0.064 11.8 1.3 7.3 5.0 0.0 3.0 2 1 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Methyltransf_12 PF08242.7 ETN98080.1 - 0.0063 16.9 0.2 0.0095 16.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Kelch_6 PF13964.1 ETN98081.1 - 1.6e-08 34.3 5.5 0.00034 20.6 0.4 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETN98081.1 - 3.9e-08 32.7 8.6 1.8e-07 30.5 0.8 4.1 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 ETN98081.1 - 1.7e-05 24.6 0.7 0.24 11.4 0.7 4.8 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.10 ETN98081.1 - 5.7e-05 22.7 3.9 0.0045 16.6 0.2 4.1 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.1 ETN98081.1 - 0.00018 21.5 0.5 0.022 14.9 0.0 3.4 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETN98081.1 - 0.031 14.0 4.8 0.47 10.2 0.3 3.7 3 1 1 4 4 4 0 Galactose oxidase, central domain DUF3819 PF12842.2 ETN98082.1 - 0.016 14.9 0.4 0.017 14.8 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) DUF2054 PF10218.4 ETN98082.1 - 0.016 15.0 1.3 0.016 15.0 0.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2054) Virul_fac_BrkB PF03631.10 ETN98083.1 - 0.014 14.7 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 Virulence factor BrkB DUF3115 PF11312.3 ETN98086.1 - 0.063 12.1 0.0 0.073 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3115) Spore_YunB PF09560.5 ETN98087.1 - 0.11 12.1 0.1 0.22 11.2 0.0 1.5 1 1 0 1 1 1 0 Sporulation protein YunB (Spo_YunB) EF_TS PF00889.14 ETN98088.1 - 0.077 12.3 0.3 0.083 12.2 0.2 1.1 1 0 0 1 1 1 0 Elongation factor TS MethyltransfD12 PF02086.10 ETN98089.1 - 3.6e-16 59.4 1.0 4.2e-16 59.1 0.1 1.5 2 0 0 2 2 2 1 D12 class N6 adenine-specific DNA methyltransferase HSDR_N_2 PF13588.1 ETN98089.1 - 0.00032 20.4 0.8 0.004 16.9 0.2 2.4 1 1 1 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) YqaJ PF09588.5 ETN98089.1 - 0.048 13.6 0.1 0.077 12.9 0.1 1.3 1 0 0 1 1 1 0 YqaJ-like viral recombinase domain DuffyBP_N PF12377.3 ETN98091.1 - 0.025 14.7 0.2 0.065 13.4 0.1 1.9 1 1 1 2 2 2 0 Duffy binding protein N terminal AAA_15 PF13175.1 ETN98091.1 - 0.032 13.2 6.1 0.039 13.0 4.2 1.0 1 0 0 1 1 1 0 AAA ATPase domain Peptidase_C14 PF00656.17 ETN98091.1 - 0.037 13.7 0.1 0.048 13.3 0.1 1.1 1 0 0 1 1 1 0 Caspase domain DUF1104 PF06518.6 ETN98091.1 - 0.049 13.7 1.9 0.078 13.1 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) NMT_C PF02799.10 ETN98091.1 - 0.11 11.8 0.8 0.19 11.0 0.5 1.4 1 1 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain DUF515 PF04415.7 ETN98091.1 - 0.43 8.7 3.1 1.3 7.1 0.7 1.6 1 1 0 2 2 2 0 Protein of unknown function (DUF515) zf-TRAF PF02176.13 ETN98092.1 - 1.8e-05 25.0 1.7 3.5e-05 24.0 1.2 1.5 1 0 0 1 1 1 1 TRAF-type zinc finger Fzo_mitofusin PF04799.8 ETN98092.1 - 0.0012 18.2 6.7 0.0012 18.2 4.7 1.7 2 1 0 2 2 2 1 fzo-like conserved region BicD PF09730.4 ETN98092.1 - 0.0087 14.4 8.6 0.012 14.0 6.0 1.2 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D NAD_binding_5 PF07994.7 ETN98092.1 - 0.036 13.5 0.6 0.043 13.3 0.4 1.1 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Syntaxin PF00804.20 ETN98092.1 - 0.13 12.4 15.3 0.048 13.8 8.8 1.7 2 0 0 2 2 2 0 Syntaxin Casc1 PF12366.3 ETN98092.1 - 0.13 11.7 5.9 0.25 10.8 4.1 1.4 1 1 0 1 1 1 0 Cancer susceptibility candidate 1 DUF972 PF06156.8 ETN98092.1 - 0.16 12.3 10.1 0.096 13.0 5.8 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF972) DUF1192 PF06698.6 ETN98092.1 - 0.19 11.5 1.3 7.3 6.4 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) MCP_N PF05581.7 ETN98092.1 - 0.21 11.7 1.8 0.3 11.2 1.2 1.2 1 0 0 1 1 1 0 Vibrio chemotaxis protein N terminus Kinesin-relat_1 PF12711.2 ETN98092.1 - 0.32 11.4 9.6 1.1 9.6 3.5 2.9 1 1 2 3 3 3 0 Kinesin motor CCDC-167 PF15188.1 ETN98092.1 - 0.57 10.1 9.1 1.3 9.0 6.3 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Pedibin PF08182.6 ETN98092.1 - 0.87 9.1 8.1 0.77 9.3 0.2 2.8 3 0 0 3 3 3 0 Pedibin/Hym-346 family Kinetocho_Slk19 PF12709.2 ETN98092.1 - 1 9.4 10.4 1.8 8.6 0.6 2.8 1 1 1 2 2 2 0 Central kinetochore-associated bZIP_1 PF00170.16 ETN98092.1 - 1.2 9.1 11.3 0.55 10.2 0.5 3.2 2 1 2 4 4 3 0 bZIP transcription factor MRP-L46 PF11788.3 ETN98092.1 - 1.2 9.8 5.6 7.3 7.2 3.9 2.0 1 1 0 1 1 1 0 39S mitochondrial ribosomal protein L46 DUF1515 PF07439.6 ETN98092.1 - 2.3 8.0 4.5 80 3.1 3.1 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) DUF904 PF06005.7 ETN98092.1 - 2.7 8.3 18.5 58 4.0 12.8 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF904) IncA PF04156.9 ETN98092.1 - 7.4 6.1 11.2 3.9 7.0 6.3 1.6 2 0 0 2 2 2 0 IncA protein LRS4 PF10422.4 ETN98092.1 - 8.3 5.6 18.3 20 4.4 12.2 2.0 2 1 0 2 2 2 0 Monopolin complex subunit LRS4 RasGEF PF00617.14 ETN98093.1 - 0.0058 16.3 0.0 0.012 15.3 0.0 1.5 2 0 0 2 2 2 1 RasGEF domain MTP18 PF10558.4 ETN98093.1 - 0.065 13.1 0.0 0.068 13.0 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) DUF87 PF01935.12 ETN98093.1 - 0.069 12.9 0.0 0.08 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF1706 PF08020.6 ETN98093.1 - 0.074 12.5 2.0 0.09 12.2 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1706) PaRep2a PF07903.6 ETN98093.1 - 0.077 12.6 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein RasGEF_N PF00618.15 ETN98093.1 - 0.13 12.3 0.2 0.3 11.1 0.1 1.6 2 0 0 2 2 2 0 RasGEF N-terminal motif HemN_C PF06969.11 ETN98093.1 - 0.15 12.1 0.0 6.5 6.8 0.0 2.1 2 0 0 2 2 2 0 HemN C-terminal domain ubiquitin PF00240.18 ETN98094.1 - 1.7e-10 40.1 0.0 3.2e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 ETN98094.1 - 0.00073 19.1 0.0 0.0015 18.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Maelstrom PF13017.1 ETN98095.1 - 0.67 9.4 6.7 1.8 8.0 1.6 2.0 1 1 1 2 2 2 0 piRNA pathway germ-plasm component DUF1635 PF07795.6 ETN98096.1 - 0.035 13.4 3.7 0.065 12.6 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) AF-4 PF05110.8 ETN98096.1 - 0.04 11.8 13.1 0.047 11.5 9.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RP-C_C PF11800.3 ETN98096.1 - 0.36 10.5 4.7 0.53 9.9 3.3 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF605 PF04652.11 ETN98096.1 - 0.37 10.1 15.1 0.44 9.9 10.4 1.1 1 0 0 1 1 1 0 Vta1 like Menin PF05053.8 ETN98096.1 - 0.52 8.4 8.0 0.68 8.0 5.5 1.1 1 0 0 1 1 1 0 Menin ABC2_membrane_3 PF12698.2 ETN98096.1 - 4.2 6.3 7.0 5.7 5.8 4.8 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Transposase_mut PF00872.13 ETN98097.1 - 0.015 13.9 0.0 0.018 13.5 0.0 1.1 1 0 0 1 1 1 0 Transposase, Mutator family RVT_1 PF00078.22 ETN98098.1 - 7.1e-05 22.2 0.0 8e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4482 PF14818.1 ETN98098.1 - 0.044 14.4 0.2 0.051 14.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) Med17 PF10156.4 ETN98098.1 - 0.074 11.3 0.2 0.082 11.1 0.1 1.0 1 0 0 1 1 1 0 Subunit 17 of Mediator complex Alpha-mann_mid PF09261.6 ETN98098.1 - 0.098 12.8 0.1 0.11 12.7 0.1 1.3 1 1 0 1 1 1 0 Alpha mannosidase, middle domain TrfA PF07042.6 ETN98098.1 - 0.12 11.1 0.2 0.12 11.1 0.1 1.1 1 0 0 1 1 1 0 TrfA protein Wbp11 PF09429.5 ETN98099.1 - 0.045 13.7 0.9 0.24 11.4 0.1 2.1 1 1 1 2 2 2 0 WW domain binding protein 11 TetR_C_8 PF14278.1 ETN98100.1 - 0.16 12.4 4.8 0.12 12.7 2.1 1.9 1 1 1 2 2 2 0 Transcriptional regulator C-terminal region WD40 PF00400.27 ETN98101.1 - 2.1e-18 65.4 0.9 6.2e-08 32.2 0.0 3.3 2 1 1 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN98101.1 - 0.056 11.5 0.9 0.99 7.4 0.1 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 SH2 PF00017.19 ETN98101.1 - 0.72 9.7 2.8 4.3 7.2 0.1 2.7 1 1 1 2 2 2 0 SH2 domain DUF3584 PF12128.3 ETN98104.1 - 0.00059 17.3 42.8 0.00059 17.3 29.7 5.5 1 1 5 6 6 6 1 Protein of unknown function (DUF3584) IncA PF04156.9 ETN98104.1 - 0.00095 18.8 15.4 0.00095 18.8 10.6 9.8 1 1 8 9 9 9 4 IncA protein DNA_pol_B_palm PF14792.1 ETN98104.1 - 0.0068 16.4 1.8 0.0068 16.4 1.2 5.0 3 1 2 5 5 5 1 DNA polymerase beta palm Filament PF00038.16 ETN98104.1 - 0.0081 15.6 176.2 0.017 14.6 26.1 8.2 1 1 6 7 7 7 4 Intermediate filament protein Nuc_N PF14448.1 ETN98104.1 - 0.34 10.4 2.8 18 5.0 0.1 3.7 4 0 0 4 4 4 0 Nuclease N terminal Fib_alpha PF08702.5 ETN98105.1 - 0.16 12.1 5.2 0.31 11.1 3.6 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family SNARE PF05739.14 ETN98106.1 - 2.9e-11 42.8 4.9 2.9e-11 42.8 3.4 2.0 2 0 0 2 2 2 1 SNARE domain DUF1359 PF07097.6 ETN98106.1 - 0.084 12.9 2.0 0.18 11.8 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1359) Med15_fungi PF05397.7 ETN98106.1 - 0.37 10.7 6.6 0.31 11.0 0.1 3.1 2 1 1 3 3 3 0 Mediator complex subunit 15 Prenyltransf PF01255.14 ETN98106.1 - 1.1 8.2 5.1 5.5 6.0 0.2 2.3 2 1 0 2 2 2 0 Putative undecaprenyl diphosphate synthase Sec20 PF03908.8 ETN98106.1 - 2 8.1 8.8 6.9 6.4 0.2 3.0 2 2 1 3 3 3 0 Sec20 DUF3513 PF12026.3 ETN98106.1 - 3.2 7.2 8.3 0.42 10.1 1.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3513) Laminin_II PF06009.7 ETN98106.1 - 3.7 7.3 9.9 0.59 9.8 1.3 2.4 2 0 0 2 2 2 0 Laminin Domain II Noelin-1 PF12308.3 ETN98106.1 - 6.8 6.5 10.2 0.19 11.5 1.2 2.5 2 2 0 2 2 2 0 Neurogenesis glycoprotein PH PF00169.24 ETN98107.1 - 0.00011 22.3 0.1 0.00052 20.1 0.1 2.3 1 1 0 1 1 1 1 PH domain PH_11 PF15413.1 ETN98107.1 - 0.016 15.4 1.6 0.016 15.4 1.1 2.9 3 2 0 3 3 3 0 Pleckstrin homology domain Fibrinogen_BP PF08017.6 ETN98108.1 - 0.12 10.5 5.8 0.13 10.4 4.0 1.0 1 0 0 1 1 1 0 Fibrinogen binding protein Annexin PF00191.15 ETN98109.1 - 2.1e-13 49.9 0.5 2.9e-08 33.4 0.1 2.6 2 0 0 2 2 2 2 Annexin DUF4615 PF15393.1 ETN98109.1 - 0.12 12.6 2.1 0.5 10.6 1.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4615) Phe_tRNA-synt_N PF02912.13 ETN98109.1 - 0.19 11.5 2.9 8.2 6.2 0.8 2.6 1 1 1 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain YkuI_C PF10388.4 ETN98109.1 - 0.22 11.2 2.9 0.45 10.1 0.4 2.0 2 0 0 2 2 2 0 EAL-domain associated signalling protein domain DUF1414 PF07208.6 ETN98109.1 - 0.28 10.9 1.5 4.1 7.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1414) CAAP1 PF15335.1 ETN98109.1 - 0.77 10.0 0.1 0.77 10.0 0.1 2.9 2 1 1 3 3 3 0 Caspase activity and apoptosis inhibitor 1 DUF3347 PF11827.3 ETN98109.1 - 3.4 7.6 6.1 2.9 7.8 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) Gpi16 PF04113.9 ETN98111.1 - 9.6e-09 33.7 0.0 1e-08 33.6 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component GFA PF04828.9 ETN98112.1 - 0.002 18.0 0.4 0.0035 17.2 0.2 1.4 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-tcix PF14952.1 ETN98112.1 - 0.3 10.4 3.9 8.4 5.8 0.0 2.8 2 1 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding DUF342 PF03961.8 ETN98114.1 - 0.0067 14.8 7.6 0.007 14.8 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF342) CBM_11 PF03425.8 ETN98114.1 - 0.038 13.6 0.6 0.052 13.2 0.4 1.1 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) DASH_Dad3 PF08656.5 ETN98114.1 - 0.059 13.0 1.2 0.059 13.0 0.1 1.7 2 0 0 2 2 2 0 DASH complex subunit Dad3 Allexi_40kDa PF05549.6 ETN98114.1 - 0.11 11.7 1.1 0.12 11.6 0.8 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein HTH_26 PF13443.1 ETN98114.1 - 0.12 12.5 0.8 0.79 9.9 0.0 2.1 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain Laminin_II PF06009.7 ETN98114.1 - 0.14 11.9 2.6 2.6 7.8 0.3 2.2 2 0 0 2 2 2 0 Laminin Domain II DUF3781 PF12636.2 ETN98115.1 - 0.039 13.9 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) NS3_envE PF02723.9 ETN98115.1 - 0.62 10.0 0.1 0.62 10.0 0.1 3.8 2 1 1 3 3 3 0 Non-structural protein NS3/Small envelope protein E RelA_SpoT PF04607.12 ETN98118.1 - 0.0016 18.3 0.1 0.0021 18.0 0.1 1.1 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins CobT_C PF11775.3 ETN98119.1 - 3.8e-52 176.8 0.1 7.2e-40 136.7 0.0 2.1 1 1 1 2 2 2 2 Cobalamin biosynthesis protein CobT VWA domain VWA PF00092.23 ETN98119.1 - 0.0026 17.5 0.0 0.51 10.0 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_CoxE PF05762.9 ETN98119.1 - 0.061 12.4 0.0 3.3 6.8 0.0 2.1 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein VWA_2 PF13519.1 ETN98119.1 - 0.067 13.2 0.0 2.7 8.0 0.0 2.2 1 1 0 1 1 1 0 von Willebrand factor type A domain DUF4584 PF15223.1 ETN98119.1 - 0.38 9.9 3.0 0.55 9.4 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4584) Wx5_PLAF3D7 PF09688.5 ETN98120.1 - 0.013 15.4 3.4 0.023 14.6 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) DUF4125 PF13526.1 ETN98120.1 - 0.041 13.4 0.1 0.062 12.8 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4125) IL28A PF15177.1 ETN98120.1 - 0.098 12.1 0.1 0.38 10.2 0.1 2.0 1 1 2 3 3 3 0 Interleukin-28A MMR_HSR1 PF01926.18 ETN98121.1 - 8.2e-06 25.7 0.3 1.9e-05 24.5 0.2 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 ETN98121.1 - 9.3e-06 24.9 0.7 4.4e-05 22.7 0.5 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 ETN98121.1 - 3.6e-05 23.6 0.7 0.085 12.6 0.0 2.1 1 1 0 2 2 2 2 Dynamin family ABC_tran PF00005.22 ETN98121.1 - 0.00016 22.0 0.1 0.00018 21.8 0.1 1.2 1 0 0 1 1 1 1 ABC transporter Miro PF08477.8 ETN98121.1 - 0.0012 19.3 0.1 0.0023 18.4 0.1 1.4 1 1 0 1 1 1 1 Miro-like protein AAA_29 PF13555.1 ETN98121.1 - 0.0025 17.2 0.2 0.0042 16.5 0.2 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 ETN98121.1 - 0.0041 16.5 0.0 0.0041 16.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 ETN98121.1 - 0.0045 16.4 0.1 0.0091 15.4 0.1 1.5 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain T2SE PF00437.15 ETN98121.1 - 0.0054 15.6 0.2 0.0081 15.0 0.2 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_28 PF13521.1 ETN98121.1 - 0.0063 16.4 0.1 0.01 15.7 0.1 1.4 2 0 0 2 2 1 1 AAA domain Septin PF00735.13 ETN98121.1 - 0.0079 15.2 0.1 0.011 14.7 0.1 1.2 1 0 0 1 1 1 1 Septin AAA_22 PF13401.1 ETN98121.1 - 0.019 15.1 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 ETN98121.1 - 0.024 14.7 0.2 0.048 13.8 0.1 1.5 1 1 0 1 1 1 0 RNA helicase DUF815 PF05673.8 ETN98121.1 - 0.034 13.0 0.3 0.042 12.7 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_23 PF13476.1 ETN98121.1 - 0.035 14.4 0.7 0.053 13.8 0.5 1.2 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 ETN98121.1 - 0.035 13.3 0.3 0.047 12.9 0.2 1.4 1 1 0 1 1 1 0 PhoH-like protein TrwB_AAD_bind PF10412.4 ETN98121.1 - 0.036 12.6 0.1 0.047 12.3 0.1 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain MCM PF00493.18 ETN98121.1 - 0.05 12.3 0.1 0.067 11.9 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family AAA_16 PF13191.1 ETN98121.1 - 0.056 13.4 0.0 0.058 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 ETN98121.1 - 0.059 13.5 0.1 0.078 13.1 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.4 ETN98121.1 - 0.061 11.8 0.1 0.063 11.8 0.1 1.1 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_19 PF13245.1 ETN98121.1 - 0.063 13.0 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain MobB PF03205.9 ETN98121.1 - 0.067 12.9 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 ETN98121.1 - 0.073 12.5 0.1 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 ETN98121.1 - 0.08 13.2 0.3 0.11 12.8 0.2 1.3 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 ETN98121.1 - 0.096 12.7 0.0 0.26 11.3 0.0 1.6 1 1 1 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 ETN98121.1 - 0.13 11.6 0.2 0.22 10.9 0.1 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.1 ETN98121.1 - 0.14 12.0 0.4 0.16 11.7 0.3 1.4 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 ETN98121.1 - 0.17 12.7 0.2 0.23 12.2 0.1 1.4 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 ETN98121.1 - 0.2 11.1 0.2 0.2 11.1 0.1 1.9 2 1 1 3 3 2 0 Ethanolamine utilisation - propanediol utilisation DUF4133 PF13571.1 ETN98125.1 - 0.096 12.9 2.0 0.15 12.3 1.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4133) zf-DHHC PF01529.15 ETN98125.1 - 2.1 7.7 5.2 2.3 7.5 3.6 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF2758 PF10957.3 ETN98131.1 - 0.27 11.0 1.6 13 5.6 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2758) 7tm_7 PF08395.7 ETN98131.1 - 0.38 9.7 4.5 0.42 9.5 3.1 1.0 1 0 0 1 1 1 0 7tm Chemosensory receptor Kelch_6 PF13964.1 ETN98132.1 - 1.2e-05 25.2 0.9 0.00028 20.9 0.1 2.4 1 1 1 2 2 2 1 Kelch motif Kelch_2 PF07646.10 ETN98132.1 - 0.00051 19.6 0.2 0.0014 18.3 0.1 1.8 1 0 0 1 1 1 1 Kelch motif Kelch_5 PF13854.1 ETN98132.1 - 0.021 14.7 0.4 0.3 11.0 0.1 2.2 2 0 0 2 2 2 0 Kelch motif Kelch_4 PF13418.1 ETN98132.1 - 0.03 14.0 0.0 0.092 12.5 0.0 1.8 2 0 0 2 2 2 0 Galactose oxidase, central domain Herpes_UL3 PF03369.8 ETN98132.1 - 0.11 12.4 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL3 protein Kelch_1 PF01344.20 ETN98132.1 - 0.11 12.0 0.1 0.11 12.0 0.1 2.5 3 0 0 3 3 3 0 Kelch motif RRM_6 PF14259.1 ETN98133.1 - 0.00021 21.2 0.0 0.00039 20.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETN98133.1 - 0.00023 20.7 0.0 0.00044 19.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETN98133.1 - 0.086 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_6 PF14259.1 ETN98134.1 - 0.00019 21.3 0.0 0.00035 20.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETN98134.1 - 0.00023 20.7 0.0 0.00039 19.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETN98134.1 - 0.08 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Sirohm_synth_C PF14823.1 ETN98134.1 - 0.11 11.8 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal RRM_5 PF13893.1 ETN98134.1 - 0.12 12.1 0.1 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VWA_2 PF13519.1 ETN98136.1 - 6.2e-11 42.7 0.0 8.3e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 ETN98136.1 - 0.038 13.1 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein PH PF00169.24 ETN98137.1 - 0.015 15.5 0.0 0.02 15.1 0.0 1.3 1 0 0 1 1 1 0 PH domain UQ_con PF00179.21 ETN98138.1 - 4.4e-05 22.9 0.4 5e-05 22.7 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 ETN98138.1 - 0.12 12.2 0.3 0.16 11.8 0.2 1.3 1 0 0 1 1 1 0 RWD domain FA_desaturase PF00487.19 ETN98139.1 - 0.27 10.6 2.6 0.47 9.8 1.3 1.6 2 0 0 2 2 2 0 Fatty acid desaturase MAD PF05557.8 ETN98139.1 - 5.9 4.8 38.8 0.47 8.4 23.8 1.3 2 0 0 2 2 2 0 Mitotic checkpoint protein HOOK PF05622.7 ETN98139.1 - 7.6 4.1 36.2 19 2.9 25.1 1.6 1 1 0 1 1 1 0 HOOK protein Macoilin PF09726.4 ETN98139.1 - 9.6 4.3 28.0 13 3.9 19.4 1.2 1 0 0 1 1 1 0 Transmembrane protein Cauli_AT PF03233.8 ETN98140.1 - 0.035 13.8 0.2 0.035 13.8 0.2 2.4 3 0 0 3 3 3 0 Aphid transmission protein zf-C4_Topoisom PF01396.14 ETN98140.1 - 0.05 13.1 2.5 3.9 7.0 0.0 3.0 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger COG5 PF10392.4 ETN98141.1 - 0.0016 18.3 10.6 0.0072 16.2 3.2 2.2 1 1 1 2 2 2 2 Golgi transport complex subunit 5 G-gamma PF00631.17 ETN98141.1 - 0.04 13.6 1.0 0.11 12.2 0.3 2.1 2 0 0 2 2 2 0 GGL domain Vac_Fusion PF02346.11 ETN98141.1 - 0.067 12.6 6.7 0.095 12.1 0.6 2.6 2 0 0 2 2 2 0 Chordopoxvirus fusion protein DUF3584 PF12128.3 ETN98141.1 - 0.1 9.8 12.4 0.14 9.4 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TMPIT PF07851.8 ETN98141.1 - 0.1 11.6 11.2 0.13 11.2 7.7 1.3 1 0 0 1 1 1 0 TMPIT-like protein HPPK PF01288.15 ETN98141.1 - 0.11 12.2 3.5 0.098 12.3 1.5 1.7 2 0 0 2 2 2 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) PI3Ka PF00613.15 ETN98141.1 - 0.13 11.4 7.7 0.41 9.7 1.1 2.4 1 1 1 2 2 2 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF2265 PF10023.4 ETN98141.1 - 0.16 11.0 1.4 0.22 10.6 0.9 1.2 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) DUF148 PF02520.12 ETN98141.1 - 0.42 10.4 13.8 0.39 10.5 7.4 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF148 DUF1664 PF07889.7 ETN98141.1 - 0.55 10.0 13.7 0.93 9.3 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 ETN98141.1 - 0.68 9.7 9.9 0.44 10.3 0.8 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus V_ATPase_I PF01496.14 ETN98141.1 - 0.82 7.4 9.3 1.1 7.0 6.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-C4pol PF14260.1 ETN98141.1 - 1.3 9.1 4.1 1.8 8.6 1.4 2.3 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta PIN_2 PF10130.4 ETN98141.1 - 1.3 9.0 6.6 1.7 8.6 3.8 1.8 1 1 1 2 2 2 0 PIN domain DUF725 PF05267.7 ETN98141.1 - 1.6 8.6 6.3 2.8 7.8 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF725) DUF19 PF01579.13 ETN98141.1 - 1.8 8.5 10.5 1.8 8.4 6.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF19) PMC2NT PF08066.7 ETN98141.1 - 2.6 8.3 8.3 8.6 6.7 0.6 2.3 2 0 0 2 2 2 0 PMC2NT (NUC016) domain DUF3505 PF12013.3 ETN98141.1 - 2.7 8.2 7.7 2.8 8.2 2.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3505) PRCC PF10253.4 ETN98141.1 - 4.1 8.0 9.5 2.1 9.0 3.6 2.0 1 1 1 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting DUF2935 PF11155.3 ETN98141.1 - 4.3 7.4 12.2 5.3 7.1 2.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Lge1 PF11488.3 ETN98141.1 - 4.9 7.4 13.3 0.41 10.8 1.9 2.7 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 DUF745 PF05335.8 ETN98141.1 - 8.1 5.9 9.3 15 5.0 6.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF745) Got1 PF04178.7 ETN98143.1 - 1.4 9.0 7.7 0.098 12.7 0.8 2.0 2 0 0 2 2 2 0 Got1/Sft2-like family WD40 PF00400.27 ETN98144.1 - 2e-50 166.9 9.7 4.4e-12 45.3 0.3 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 ETN98144.1 - 1.7e-09 37.6 0.2 6.2e-06 26.0 0.0 3.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 ETN98144.1 - 6.3e-06 25.8 0.1 8.3e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 PQQ-like domain Nup160 PF11715.3 ETN98144.1 - 5e-05 21.6 0.3 0.13 10.3 0.0 3.4 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETN98144.1 - 5.2e-05 21.7 0.0 0.011 14.1 0.0 2.2 1 1 1 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.7 ETN98144.1 - 0.0057 16.3 2.6 18 5.1 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Mid2 PF04478.7 ETN98144.1 - 0.018 14.4 0.3 0.075 12.4 0.1 2.2 2 1 0 2 2 2 0 Mid2 like cell wall stress sensor Proteasome_A_N PF10584.4 ETN98144.1 - 0.02 14.1 5.8 1.1 8.6 0.0 4.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Hira PF07569.6 ETN98144.1 - 0.033 13.4 0.2 11 5.0 0.0 3.4 1 1 3 4 4 4 0 TUP1-like enhancer of split DUF572 PF04502.8 ETN98145.1 - 0.0066 15.7 4.9 0.0085 15.3 3.4 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) PsbW PF07123.7 ETN98145.1 - 5.5 7.0 5.4 7.2 6.6 3.4 1.4 1 1 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) WD40 PF00400.27 ETN98146.1 - 0.00011 21.8 0.5 0.00034 20.3 0.4 1.8 2 0 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETN98146.1 - 0.12 10.4 0.0 0.12 10.4 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 NACHT PF05729.7 ETN98147.1 - 1.5e-08 34.4 0.0 2.4e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Sulfate_transp PF00916.15 ETN98148.1 - 2.2e-23 82.6 0.2 4.1e-23 81.7 0.1 1.3 1 0 0 1 1 1 1 Sulfate transporter family HTH_26 PF13443.1 ETN98149.1 - 1.9 8.7 6.3 3.5 7.9 4.3 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain TPR_12 PF13424.1 ETN98150.1 - 1.2e-38 130.8 0.4 2.1e-25 88.4 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETN98150.1 - 4.4e-22 77.5 6.4 6.7e-16 57.6 1.2 1.6 1 1 1 2 2 2 2 TPR repeat TPR_10 PF13374.1 ETN98150.1 - 5.9e-20 70.5 0.0 8e-09 35.1 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETN98150.1 - 4.6e-18 63.9 9.9 2.1e-09 36.5 0.4 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETN98150.1 - 1.9e-16 58.5 8.7 9.6e-08 31.2 1.7 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETN98150.1 - 3.1e-16 57.8 0.0 1.2e-08 34.1 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETN98150.1 - 5.5e-14 50.8 5.0 1.3e-06 27.9 0.1 2.5 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETN98150.1 - 8e-10 38.1 2.8 0.0005 20.0 0.0 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETN98150.1 - 9.5e-06 25.7 0.0 0.05 14.0 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 ETN98150.1 - 1.4e-05 25.1 1.2 0.00023 21.2 0.3 2.0 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 ETN98150.1 - 1.4e-05 24.7 1.5 0.066 13.0 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETN98150.1 - 2.2e-05 24.6 0.0 0.23 12.2 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETN98150.1 - 0.00019 22.0 0.0 0.032 14.9 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat MIT PF04212.13 ETN98150.1 - 0.00083 19.1 2.7 0.12 12.3 0.2 2.2 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain DUF627 PF04781.7 ETN98150.1 - 0.0016 18.0 0.2 0.47 10.0 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF627) RPN7 PF10602.4 ETN98150.1 - 0.0032 16.8 0.1 0.0046 16.3 0.1 1.1 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PPR PF01535.15 ETN98150.1 - 0.0038 17.0 1.3 0.73 9.9 0.1 2.3 2 0 0 2 2 2 1 PPR repeat Sel1 PF08238.7 ETN98150.1 - 0.008 16.7 0.3 0.57 10.9 0.1 2.4 2 0 0 2 2 2 1 Sel1 repeat SNAP PF14938.1 ETN98150.1 - 0.0081 15.3 0.2 0.014 14.5 0.2 1.4 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP Pep3_Vps18 PF05131.9 ETN98150.1 - 0.016 14.6 0.0 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 Pep3/Vps18/deep orange family TPR_19 PF14559.1 ETN98150.1 - 0.024 14.9 0.0 0.076 13.3 0.0 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETN98150.1 - 0.066 13.1 1.2 1.8 8.5 0.1 2.3 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat PPR_2 PF13041.1 ETN98150.1 - 0.11 12.5 0.3 16 5.5 0.0 2.2 2 0 0 2 2 2 0 PPR repeat family Lumazine_bd PF12870.2 ETN98150.1 - 0.16 12.0 0.3 11 6.1 0.0 2.1 2 0 0 2 2 2 0 Lumazine-binding domain Ubiq-assoc PF09145.5 ETN98150.1 - 2.7 7.9 4.9 2.1 8.2 0.3 2.8 2 2 1 3 3 3 0 Ubiquitin-associated DUF2854 PF11016.3 ETN98151.1 - 0.099 12.1 0.1 0.14 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) SR-25 PF10500.4 ETN98153.1 - 0.029 13.8 8.3 0.052 13.0 5.8 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Daxx PF03344.10 ETN98153.1 - 0.2 10.1 20.4 0.22 9.9 14.2 1.0 1 0 0 1 1 1 0 Daxx Family SLX9 PF15341.1 ETN98153.1 - 1.1 9.7 11.3 0.98 9.8 6.1 1.9 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 Sigma70_ner PF04546.8 ETN98154.1 - 0.0012 18.4 5.0 0.0021 17.7 3.4 1.3 1 0 0 1 1 1 1 Sigma-70, non-essential region Tom22 PF04281.8 ETN98154.1 - 0.082 12.4 2.1 0.14 11.6 1.4 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 PBP1_TM PF14812.1 ETN98154.1 - 0.21 11.9 12.8 0.32 11.3 8.9 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LAT PF15234.1 ETN98154.1 - 0.86 9.0 6.3 1.2 8.5 4.3 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells DUF506 PF04720.7 ETN98154.1 - 1.9 8.0 4.0 2.2 7.8 1.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF506) CDC45 PF02724.9 ETN98154.1 - 2.6 5.9 8.3 3.2 5.6 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein BTV_NS2 PF04514.7 ETN98154.1 - 7 5.4 7.7 1.3 7.7 3.0 1.5 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 Sigma_reg_N PF13800.1 ETN98155.1 - 0.035 14.1 0.2 0.071 13.1 0.1 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal MAGE PF01454.14 ETN98155.1 - 0.056 12.7 1.1 0.067 12.5 0.8 1.1 1 0 0 1 1 1 0 MAGE family DUF3989 PF13150.1 ETN98155.1 - 0.11 12.0 0.1 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) DUF1828 PF08861.5 ETN98155.1 - 0.79 9.4 5.9 6.7 6.4 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF1828 PEX11 PF05648.9 ETN98155.1 - 0.79 8.9 4.4 1.7 7.8 2.8 1.7 1 1 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) DUF3959 PF13105.1 ETN98155.1 - 7.7 5.7 8.0 13 5.0 5.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3959) Zip PF02535.17 ETN98156.1 - 0.0032 16.5 3.1 0.0032 16.5 2.2 2.1 2 0 0 2 2 2 1 ZIP Zinc transporter Raftlin PF15250.1 ETN98156.1 - 0.83 8.1 8.6 0.45 8.9 1.9 2.0 2 0 0 2 2 2 0 Raftlin Spore_YhcN_YlaJ PF09580.5 ETN98156.1 - 0.96 9.5 16.6 0.043 13.9 4.6 2.2 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Pex14_N PF04695.8 ETN98156.1 - 1.7 8.6 7.0 0.14 12.2 0.3 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PDR_CDR PF06422.7 ETN98157.1 - 2.3 7.9 5.0 0.44 10.2 0.8 1.8 2 0 0 2 2 2 0 CDR ABC transporter Glyco_transf_49 PF13896.1 ETN98158.1 - 1.3e-08 34.3 1.2 3.3e-08 32.9 0.1 2.3 2 1 0 2 2 2 1 Glycosyl-transferase for dystroglycan RNase_H PF00075.19 ETN98159.1 - 7e-05 23.1 0.0 0.0003 21.1 0.0 1.9 2 1 0 2 2 2 1 RNase H Fz PF01392.17 ETN98159.1 - 0.087 13.1 0.7 5.5 7.3 0.0 2.3 1 1 1 2 2 2 0 Fz domain Sec62 PF03839.11 ETN98160.1 - 0.024 14.0 0.0 0.028 13.8 0.0 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Cytomega_UL20A PF05984.7 ETN98160.1 - 0.14 12.3 2.0 0.26 11.4 1.4 1.4 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein PGK PF00162.14 ETN98161.1 - 9.8e-96 320.6 0.4 1.6e-95 319.9 0.3 1.3 1 1 0 1 1 1 1 Phosphoglycerate kinase K_oxygenase PF13434.1 ETN98161.1 - 0.057 12.3 0.1 0.34 9.7 0.1 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) 7TMR-HDED PF07697.6 ETN98163.1 - 0.0043 16.7 0.2 0.0053 16.5 0.2 1.2 1 0 0 1 1 1 1 7TM-HD extracellular UPF0137 PF03677.8 ETN98163.1 - 0.034 13.6 2.8 0.055 12.9 1.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) DUF1764 PF08576.5 ETN98163.1 - 0.28 11.9 4.4 0.77 10.5 3.0 1.8 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) EcoR124_C PF12008.3 ETN98163.1 - 0.94 8.6 6.2 1.3 8.1 4.3 1.2 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal CDC37_N PF03234.9 ETN98163.1 - 3.5 7.9 7.2 4.4 7.5 4.8 1.3 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Tat PF00539.13 ETN98164.1 - 1.6 8.4 6.9 4.4 6.9 4.8 1.7 1 0 0 1 1 1 0 Transactivating regulatory protein (Tat) NMN_transporter PF04973.7 ETN98165.1 - 0.19 11.1 7.4 0.1 12.0 3.8 1.6 1 1 1 2 2 2 0 Nicotinamide mononucleotide transporter DUF4512 PF14975.1 ETN98165.1 - 0.46 11.3 8.7 0.83 10.5 6.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) DUF4162 PF13732.1 ETN98166.1 - 0.044 14.2 1.9 0.074 13.5 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4162) z-alpha PF02295.12 ETN98167.1 - 0.035 13.8 0.0 0.073 12.8 0.0 1.6 1 0 0 1 1 1 0 Adenosine deaminase z-alpha domain HSP70 PF00012.15 ETN98168.1 - 8.1e-06 24.0 0.0 0.00012 20.1 0.0 2.2 2 0 0 2 2 2 1 Hsp70 protein Hydantoinase_A PF01968.13 ETN98168.1 - 0.029 13.4 0.0 0.15 11.1 0.0 2.0 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase TelA PF05816.6 ETN98168.1 - 0.079 11.6 0.8 0.16 10.6 0.5 1.5 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) PRKCSH_1 PF13015.1 ETN98170.1 - 8.9e-08 31.7 0.3 1.5e-07 30.9 0.2 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.5 ETN98170.1 - 0.025 13.8 0.1 0.028 13.6 0.1 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 CIMR PF00878.13 ETN98170.1 - 0.035 13.8 0.4 0.46 10.2 0.1 2.3 2 0 0 2 2 2 0 Cation-independent mannose-6-phosphate receptor repeat GGDEF PF00990.16 ETN98171.1 - 0.00011 21.8 0.7 0.0003 20.4 0.1 1.8 2 0 0 2 2 2 1 GGDEF domain TPR_2 PF07719.12 ETN98172.1 - 0.025 14.4 0.0 0.063 13.2 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4591 PF15261.1 ETN98173.1 - 0.42 10.8 5.9 0.075 13.2 1.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4591) WD40 PF00400.27 ETN98174.1 - 9.8e-23 79.1 2.5 1.2e-11 44.0 0.1 4.0 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETN98174.1 - 0.0039 15.3 0.0 0.0041 15.3 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETN98174.1 - 0.0087 14.8 1.5 0.071 11.8 0.5 2.2 1 1 1 2 2 2 1 Nup133 N terminal like eIF2A PF08662.6 ETN98174.1 - 0.032 13.9 0.0 0.051 13.2 0.0 1.4 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 ETN98174.1 - 0.05 12.6 0.0 0.07 12.2 0.0 1.2 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal DUF3816 PF12822.2 ETN98175.1 - 0.086 12.7 0.1 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) YajC PF02699.10 ETN98175.1 - 0.68 9.6 2.7 1.5 8.5 1.9 1.6 1 0 0 1 1 1 0 Preprotein translocase subunit TPR_12 PF13424.1 ETN98177.1 - 1.8e-37 127.1 8.7 6e-21 74.1 0.9 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETN98177.1 - 1.6e-27 93.9 23.9 2e-08 33.4 1.8 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETN98177.1 - 2.7e-24 84.3 0.1 9.7e-08 31.7 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETN98177.1 - 1.6e-22 78.9 18.8 4.1e-14 51.9 3.3 3.0 2 1 0 3 3 3 3 TPR repeat TPR_2 PF07719.12 ETN98177.1 - 1.4e-18 65.2 17.8 1.2e-07 31.1 1.4 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETN98177.1 - 1.7e-17 61.7 6.1 1.5e-05 24.4 0.0 4.3 3 1 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETN98177.1 - 1.9e-16 58.4 25.1 2.3e-06 26.9 1.5 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETN98177.1 - 8.4e-12 44.3 14.3 0.0028 17.7 0.1 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETN98177.1 - 6.4e-11 41.9 1.8 0.031 14.7 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETN98177.1 - 9.6e-11 41.3 0.0 0.024 15.2 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETN98177.1 - 1.4e-09 38.3 0.1 0.00011 22.7 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat SNAP PF14938.1 ETN98177.1 - 2.7e-07 30.0 3.4 3.8e-07 29.5 2.4 1.3 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP DUF627 PF04781.7 ETN98177.1 - 2.9e-06 26.8 5.8 0.077 12.6 0.0 3.6 3 1 1 4 4 4 2 Protein of unknown function (DUF627) SHNi-TPR PF10516.4 ETN98177.1 - 4.6e-06 25.7 0.1 0.14 11.4 0.0 3.3 3 0 0 3 3 3 2 SHNi-TPR Apc3 PF12895.2 ETN98177.1 - 7.1e-06 26.0 13.5 0.011 15.8 2.1 3.4 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 ETN98177.1 - 0.00029 20.6 10.5 0.076 12.9 0.2 3.9 4 0 0 4 4 4 2 MIT (microtubule interacting and transport) domain TPR_19 PF14559.1 ETN98177.1 - 0.0015 18.7 0.7 0.45 10.8 0.0 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.1 ETN98177.1 - 0.0061 16.6 0.4 5.2 7.2 0.0 3.1 1 1 1 3 3 3 1 Tetratricopeptide repeat DUF3296 PF11726.3 ETN98177.1 - 0.0063 16.0 0.2 4.7 6.7 0.0 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF3296) Nse5 PF08691.5 ETN98177.1 - 0.013 14.0 1.9 0.37 9.2 0.2 2.1 1 1 1 2 2 2 0 DNA repair proteins Nse5 and Nse6 DUF2225 PF09986.4 ETN98177.1 - 0.028 13.8 8.6 0.19 11.1 1.7 2.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) Sel1 PF08238.7 ETN98177.1 - 0.095 13.3 7.9 0.76 10.5 0.6 3.6 4 0 0 4 4 3 0 Sel1 repeat NSF PF02071.15 ETN98177.1 - 0.18 12.4 5.2 11 7.0 0.0 4.4 4 0 0 4 4 3 0 Aromatic-di-Alanine (AdAR) repeat DUF3235 PF11574.3 ETN98177.1 - 0.21 11.8 4.3 0.12 12.6 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3235) OEP PF02321.13 ETN98177.1 - 0.22 11.0 5.4 3.9 7.0 0.4 2.7 1 1 1 2 2 2 0 Outer membrane efflux protein EzrA PF06160.7 ETN98177.1 - 0.96 7.5 8.8 3.4 5.7 0.2 3.3 4 0 0 4 4 4 0 Septation ring formation regulator, EzrA UVR PF02151.14 ETN98177.1 - 1 8.9 4.7 5.4 6.6 0.1 3.4 3 1 1 4 4 4 0 UvrB/uvrC motif Ubiq-assoc PF09145.5 ETN98177.1 - 1.2 9.0 11.7 3.3 7.6 0.1 4.3 4 1 0 4 4 3 0 Ubiquitin-associated Phage_connect_1 PF05135.8 ETN98178.1 - 0.04 14.1 0.1 0.06 13.5 0.1 1.4 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein Kelch_6 PF13964.1 ETN98179.1 - 0.09 12.9 0.0 0.42 10.8 0.0 2.1 2 1 1 3 3 3 0 Kelch motif DUF1387 PF07139.6 ETN98181.1 - 3.3 7.2 6.9 3.8 7.0 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Choline_sulf_C PF12411.3 ETN98182.1 - 0.0031 17.3 0.2 0.026 14.3 0.1 2.3 2 0 0 2 2 2 1 Choline sulfatase enzyme C terminal RNase_Zc3h12a PF11977.3 ETN98182.1 - 0.045 13.5 0.1 0.055 13.2 0.1 1.2 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain Ank_2 PF12796.2 ETN98183.1 - 0.0077 16.5 1.8 0.067 13.5 1.2 2.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) DUF4211 PF13926.1 ETN98183.1 - 0.0094 15.3 0.7 0.031 13.6 0.3 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4211) Hema_stalk PF08720.5 ETN98184.1 - 0.008 15.7 0.5 0.01 15.3 0.3 1.2 1 0 0 1 1 1 1 Influenza C hemagglutinin stalk Latrotoxin_C PF15658.1 ETN98184.1 - 0.019 14.7 1.3 0.1 12.4 0.4 2.0 1 1 1 2 2 2 0 Latrotoxin C-terminal domain Aegerolysin PF06355.8 ETN98184.1 - 0.021 14.6 0.2 0.025 14.4 0.1 1.1 1 0 0 1 1 1 0 Aegerolysin BCAS2 PF05700.6 ETN98184.1 - 0.053 12.9 1.8 0.057 12.8 1.3 1.1 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) MAP65_ASE1 PF03999.7 ETN98184.1 - 0.07 11.7 3.0 0.081 11.5 2.1 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF4014 PF13198.1 ETN98185.1 - 0.071 13.5 0.6 0.31 11.4 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4014) BRAP2 PF07576.7 ETN98185.1 - 0.082 12.4 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 BRCA1-associated protein 2 Mnd1 PF03962.10 ETN98186.1 - 0.0056 16.3 1.9 0.007 16.0 1.3 1.3 1 0 0 1 1 1 1 Mnd1 family GAS PF13851.1 ETN98186.1 - 0.0072 15.5 6.2 0.0079 15.4 4.3 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.6 ETN98186.1 - 0.0074 15.7 8.2 0.0098 15.3 5.7 1.4 1 1 0 1 1 1 1 Phage minor structural protein GP20 HOOK PF05622.7 ETN98186.1 - 0.0076 14.1 6.0 0.0078 14.0 4.2 1.0 1 0 0 1 1 1 1 HOOK protein TetR_C_4 PF08359.6 ETN98186.1 - 0.0082 16.0 2.9 0.011 15.6 2.0 1.2 1 0 0 1 1 1 1 YsiA-like protein, C-terminal region Myosin_tail_1 PF01576.14 ETN98186.1 - 0.01 13.6 2.7 0.011 13.4 1.9 1.1 1 0 0 1 1 1 0 Myosin tail NPV_P10 PF05531.7 ETN98186.1 - 0.012 15.7 4.3 0.017 15.3 2.8 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 ETN98186.1 - 0.015 14.8 7.1 0.019 14.5 4.9 1.3 1 1 0 1 1 1 0 IncA protein MutS_IV PF05190.13 ETN98186.1 - 0.018 15.2 3.2 0.028 14.5 2.2 1.4 1 0 0 1 1 1 0 MutS family domain IV WEMBL PF05701.6 ETN98186.1 - 0.021 13.3 0.6 0.025 13.0 0.4 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Perilipin PF03036.11 ETN98186.1 - 0.026 13.3 0.1 0.029 13.1 0.1 1.1 1 0 0 1 1 1 0 Perilipin family LcrV PF04792.7 ETN98186.1 - 0.034 13.1 1.0 0.038 13.0 0.7 1.1 1 0 0 1 1 1 0 V antigen (LcrV) protein L31 PF09784.4 ETN98186.1 - 0.036 14.1 0.9 0.049 13.6 0.6 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 Hemagglutinin PF00509.13 ETN98186.1 - 0.039 12.1 4.7 0.046 11.8 3.2 1.4 1 1 0 1 1 1 0 Haemagglutinin Hormone_1 PF00103.15 ETN98186.1 - 0.044 13.1 5.1 0.031 13.6 2.5 1.5 1 1 1 2 2 2 0 Somatotropin hormone family DUF3452 PF11934.3 ETN98186.1 - 0.05 12.9 3.0 0.064 12.5 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) DUF3734 PF12536.3 ETN98186.1 - 0.051 13.6 0.5 0.078 13.1 0.3 1.3 1 0 0 1 1 1 0 Patatin phospholipase COQ7 PF03232.8 ETN98186.1 - 0.064 12.7 1.2 0.086 12.3 0.9 1.2 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 Pox_A_type_inc PF04508.7 ETN98186.1 - 0.07 12.9 1.0 0.38 10.6 0.3 2.5 1 1 1 2 2 2 0 Viral A-type inclusion protein repeat Cauli_AT PF03233.8 ETN98186.1 - 0.073 12.7 10.4 0.08 12.6 3.3 2.1 1 1 1 2 2 2 0 Aphid transmission protein SF-assemblin PF06705.6 ETN98186.1 - 0.089 11.9 6.6 0.099 11.7 4.6 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin HSBP1 PF06825.7 ETN98186.1 - 0.089 12.3 2.0 0.16 11.5 1.4 1.6 1 1 0 1 1 1 0 Heat shock factor binding protein 1 DUF342 PF03961.8 ETN98186.1 - 0.093 11.1 4.0 0.1 11.0 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1664 PF07889.7 ETN98186.1 - 0.1 12.3 3.7 0.1 12.4 1.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.6 ETN98186.1 - 0.11 12.3 1.2 0.21 11.4 0.3 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Sec2p PF06428.6 ETN98186.1 - 0.12 12.2 3.3 0.19 11.5 2.3 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Med9 PF07544.8 ETN98186.1 - 0.14 11.9 3.3 0.056 13.1 0.7 1.6 2 0 0 2 2 1 0 RNA polymerase II transcription mediator complex subunit 9 AATF-Che1 PF13339.1 ETN98186.1 - 0.18 11.9 3.1 0.25 11.4 2.2 1.4 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Syntaxin PF00804.20 ETN98186.1 - 0.24 11.5 6.9 0.44 10.7 4.8 1.4 1 0 0 1 1 1 0 Syntaxin SNARE PF05739.14 ETN98186.1 - 0.28 10.9 4.8 0.54 9.9 3.3 1.6 1 1 0 1 1 1 0 SNARE domain HAP1_N PF04849.8 ETN98186.1 - 0.31 9.9 8.0 0.45 9.4 5.0 1.6 1 1 1 2 2 2 0 HAP1 N-terminal conserved region SRP1_TIP1 PF00660.12 ETN98186.1 - 0.36 10.6 1.9 2.9 7.7 0.4 2.6 1 1 1 2 2 2 0 Seripauperin and TIP1 family Allexi_40kDa PF05549.6 ETN98186.1 - 0.81 8.9 4.6 0.98 8.6 3.0 1.3 1 1 0 1 1 1 0 Allexivirus 40kDa protein Fib_alpha PF08702.5 ETN98186.1 - 1.6 8.8 11.1 2 8.5 7.7 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FlxA PF14282.1 ETN98186.1 - 1.6 8.7 10.5 3.5 7.6 7.3 1.7 1 1 0 1 1 1 0 FlxA-like protein BLOC1_2 PF10046.4 ETN98186.1 - 2 8.6 9.7 1.3 9.1 4.3 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.10 ETN98186.1 - 2.7 7.5 6.8 4.7 6.7 4.7 1.6 1 1 0 1 1 1 0 Septum formation initiator DUF755 PF05501.6 ETN98186.1 - 5.6 7.0 11.3 3.9 7.5 6.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF755) XhlA PF10779.4 ETN98186.1 - 5.9 6.8 7.7 2.6 8.0 1.6 2.3 2 0 0 2 2 2 0 Haemolysin XhlA SapB_1 PF05184.10 ETN98186.1 - 9.2 6.2 8.8 13 5.7 0.5 3.3 4 0 0 4 4 4 0 Saposin-like type B, region 1 Ecotin PF03974.8 ETN98187.1 - 0.79 9.4 6.2 1.4 8.6 4.3 1.5 1 0 0 1 1 1 0 Ecotin Pox_A_type_inc PF04508.7 ETN98187.1 - 2.3 8.2 5.9 4.3 7.3 0.1 3.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Chisel PF15355.1 ETN98188.1 - 0.088 12.8 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Stretch-responsive small skeletal muscle X protein, Chisel T5orf172 PF10544.4 ETN98190.1 - 0.002 18.4 1.7 0.0036 17.6 0.6 1.8 2 0 0 2 2 2 1 T5orf172 domain Hc1 PF07432.8 ETN98190.1 - 0.071 13.2 1.2 0.12 12.4 0.8 1.4 1 0 0 1 1 1 0 Histone H1-like protein Hc1 Amidase PF01425.16 ETN98190.1 - 0.15 10.8 0.3 0.17 10.6 0.2 1.0 1 0 0 1 1 1 0 Amidase DUF3972 PF13118.1 ETN98191.1 - 0.05 13.6 0.1 0.064 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) DUF1453 PF07301.6 ETN98192.1 - 0.03 14.2 0.0 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1453) ETRAMP PF09716.5 ETN98192.1 - 0.031 14.2 0.5 0.042 13.7 0.4 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) BAR_2 PF10455.4 ETN98192.1 - 0.031 13.1 0.2 0.034 13.0 0.2 1.0 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Potyvirid-P3 PF13608.1 ETN98192.1 - 0.044 12.8 0.1 0.048 12.7 0.0 1.0 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein DUF819 PF05684.7 ETN98192.1 - 0.065 12.0 0.0 0.071 11.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF819) CRA PF06589.6 ETN98192.1 - 0.077 12.3 0.3 0.092 12.0 0.2 1.1 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Nucleoside_tran PF01733.13 ETN98192.1 - 0.1 11.7 0.1 0.1 11.7 0.0 1.0 1 0 0 1 1 1 0 Nucleoside transporter Ribosomal_L29 PF00831.18 ETN98193.1 - 0.00024 20.7 0.6 0.49 10.1 0.1 2.3 2 0 0 2 2 2 2 Ribosomal L29 protein Mpv17_PMP22 PF04117.7 ETN98193.1 - 0.00049 19.6 0.9 6.6 6.4 0.0 3.9 2 2 2 4 4 4 1 Mpv17 / PMP22 family HEAT_2 PF13646.1 ETN98193.1 - 0.00078 19.6 0.0 0.051 13.8 0.0 1.9 1 1 1 2 2 2 2 HEAT repeats TetR_C_9 PF14514.1 ETN98193.1 - 0.0021 17.8 0.2 1.2 8.9 0.0 2.3 2 0 0 2 2 2 2 Transcriptional regulator, TetR, C-terminal CLASP_N PF12348.3 ETN98193.1 - 0.0041 16.5 0.3 2.2 7.5 0.0 2.2 2 0 0 2 2 2 2 CLASP N terminal DDE_Tnp_Tn3 PF01526.12 ETN98193.1 - 0.0046 15.6 1.2 0.86 8.1 0.1 2.3 2 0 0 2 2 2 2 Tn3 transposase DDE domain HEAT_EZ PF13513.1 ETN98193.1 - 0.0049 17.3 0.0 2.7 8.5 0.0 2.8 3 0 0 3 3 3 1 HEAT-like repeat Npa1 PF11707.3 ETN98193.1 - 0.0065 15.5 1.5 0.091 11.7 0.1 2.0 1 1 1 2 2 2 1 Ribosome 60S biogenesis N-terminal HEAT PF02985.17 ETN98193.1 - 0.0077 16.2 0.8 2.6 8.3 0.0 3.8 4 0 0 4 4 3 1 HEAT repeat Syntaxin-18_N PF10496.4 ETN98193.1 - 0.011 15.5 0.1 5.5 6.9 0.0 2.3 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus DUF1804 PF08822.6 ETN98193.1 - 0.012 15.3 0.4 0.15 11.7 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1804) CCDC32 PF14989.1 ETN98193.1 - 0.013 15.3 0.9 2.1 8.2 0.1 2.1 1 1 1 2 2 2 0 Coiled-coil domain containing 32 DUF1024 PF06260.7 ETN98193.1 - 0.041 14.0 0.3 2.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1024) N_Asn_amidohyd PF14736.1 ETN98193.1 - 0.049 12.5 0.8 2 7.1 0.0 2.0 1 1 1 2 2 2 0 Protein N-terminal asparagine amidohydrolase Aldo_ket_red PF00248.16 ETN98193.1 - 0.058 12.2 2.0 4 6.1 0.2 2.4 1 1 2 3 3 3 0 Aldo/keto reductase family Rsa3 PF14615.1 ETN98193.1 - 0.48 9.7 3.2 3.8 6.8 0.3 2.4 2 0 0 2 2 2 0 Ribosome-assembly protein 3 DUF1162 PF06650.7 ETN98194.1 - 3.2e-28 98.7 0.0 6e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1162) C2 PF00168.25 ETN98194.1 - 6.1e-16 58.0 0.0 3.1e-15 55.7 0.0 2.3 2 0 0 2 2 2 1 C2 domain SnAC PF14619.1 ETN98195.1 - 0.24 11.5 3.7 0.39 10.9 2.6 1.3 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex Peptidase_S49_N PF08496.5 ETN98195.1 - 0.39 10.5 3.3 0.59 9.9 2.3 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Dynamin_N PF00350.18 ETN98196.1 - 0.29 10.9 0.0 0.29 10.9 0.0 4.7 5 0 0 5 5 5 0 Dynamin family VWA_2 PF13519.1 ETN98197.1 - 6e-12 45.9 0.0 9.1e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 ETN98197.1 - 0.0013 18.4 0.0 0.0036 17.0 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 ETN98197.1 - 0.0063 16.3 0.1 0.038 13.8 0.0 2.0 2 0 0 2 2 2 1 vWA found in TerF C terminus DUF2201 PF09967.4 ETN98197.1 - 0.027 14.4 0.0 9.7 6.2 0.0 2.4 2 0 0 2 2 2 0 VWA-like domain (DUF2201) VWA_CoxE PF05762.9 ETN98197.1 - 0.03 13.4 0.0 5.8 5.9 0.0 2.2 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein Peptidase_S49_N PF08496.5 ETN98197.1 - 0.059 13.1 0.3 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ssl1 PF04056.9 ETN98197.1 - 0.09 12.3 0.2 2.5 7.6 0.0 2.2 2 0 0 2 2 2 0 Ssl1-like LRR_1 PF00560.28 ETN98198.1 - 1.8e-09 36.3 19.1 0.039 13.9 0.3 6.5 5 1 1 6 6 6 5 Leucine Rich Repeat LRR_7 PF13504.1 ETN98198.1 - 6.8e-09 34.4 14.5 0.099 12.9 0.1 6.6 6 0 0 6 6 6 4 Leucine rich repeat LRR_4 PF12799.2 ETN98198.1 - 3.1e-07 29.8 19.3 0.062 12.9 0.2 5.2 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETN98198.1 - 2.7e-06 27.0 15.9 0.023 14.4 2.4 4.8 2 1 1 4 4 4 4 Leucine rich repeat LRR_6 PF13516.1 ETN98198.1 - 0.00013 21.6 20.3 0.2 11.8 0.1 5.9 6 0 0 6 6 6 3 Leucine Rich repeat Brix PF04427.13 ETN98199.1 - 0.19 11.4 1.5 0.21 11.2 1.1 1.0 1 0 0 1 1 1 0 Brix domain Apc9 PF12856.2 ETN98200.1 - 0.087 12.9 3.3 0.081 13.0 0.7 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 9 HEAT_2 PF13646.1 ETN98202.1 - 8.7e-12 45.1 0.0 5.4e-06 26.5 0.0 2.7 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.17 ETN98202.1 - 4.3e-10 38.8 0.0 0.0017 18.2 0.0 4.1 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 ETN98202.1 - 0.00014 22.2 0.0 2 8.9 0.0 3.5 3 0 0 3 3 3 2 HEAT-like repeat DUF2435 PF10363.4 ETN98202.1 - 0.00024 20.9 0.7 0.0056 16.5 0.0 3.2 2 2 0 3 3 3 1 Protein of unknown function (DUF2435) DUF2487 PF10673.4 ETN98202.1 - 0.0014 18.4 0.1 0.0044 16.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2487) DUF3826 PF12875.2 ETN98202.1 - 0.0014 18.3 0.7 0.0037 17.0 0.2 2.0 1 1 0 2 2 2 1 Protein of unknown function (DUF3826) Cnd1 PF12717.2 ETN98202.1 - 0.0056 16.5 5.3 0.31 10.8 3.5 2.7 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 CRAL_TRIO_2 PF13716.1 ETN98202.1 - 0.017 15.0 2.0 1.2 9.0 0.0 2.8 1 1 2 3 3 3 0 Divergent CRAL/TRIO domain FGase PF05013.7 ETN98202.1 - 0.029 14.2 0.0 0.041 13.7 0.0 1.2 1 0 0 1 1 1 0 N-formylglutamate amidohydrolase DUF2777 PF10949.3 ETN98202.1 - 0.034 13.8 0.5 0.1 12.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2777) DUF3554 PF12074.3 ETN98202.1 - 0.037 13.4 5.1 0.039 13.3 0.8 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3554) Activator-TraM PF11657.3 ETN98202.1 - 0.072 12.5 0.6 0.42 10.0 0.0 2.3 3 0 0 3 3 3 0 Transcriptional activator TraM BP28CT PF08146.7 ETN98202.1 - 0.078 12.7 2.5 0.13 11.9 0.2 2.4 2 1 0 2 2 2 0 BP28CT (NUC211) domain DUF3349 PF11829.3 ETN98202.1 - 0.093 13.1 0.1 13 6.3 0.0 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF3349) Vac14_Fab1_bd PF12755.2 ETN98202.1 - 0.093 13.1 0.1 1.1 9.7 0.0 2.4 1 1 2 3 3 3 0 Vacuolar 14 Fab1-binding region NLE PF08154.7 ETN98202.1 - 0.12 12.3 1.8 54 3.8 0.1 3.7 3 1 0 3 3 3 0 NLE (NUC135) domain Urb2 PF10441.4 ETN98202.1 - 0.13 11.8 2.6 6.1 6.3 0.1 2.8 3 1 0 3 3 3 0 Urb2/Npa2 family NACHT PF05729.7 ETN98203.1 - 9.3e-10 38.4 0.0 1.6e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 NACHT domain DUF3735 PF12537.3 ETN98203.1 - 0.24 11.4 2.3 0.47 10.5 0.3 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3735) Hexapep PF00132.19 ETN98204.1 - 7e-05 22.1 0.0 0.00086 18.7 0.0 2.6 1 1 0 1 1 1 1 Bacterial transferase hexapeptide (six repeats) PIP5K PF01504.13 ETN98208.1 - 5.6e-22 78.0 0.4 8.1e-22 77.5 0.3 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase C_GCAxxG_C_C PF09719.5 ETN98208.1 - 0.064 13.0 0.6 0.1 12.4 0.4 1.3 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) PIP5K PF01504.13 ETN98209.1 - 4.1e-29 101.4 0.1 5.8e-29 100.9 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Ribonuclease_3 PF00636.21 ETN98210.1 - 1.5e-11 44.7 0.0 5.2e-11 43.0 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 ETN98210.1 - 1.3e-09 38.1 0.0 2.4e-09 37.2 0.0 1.4 1 1 0 1 1 1 1 Ribonuclease-III-like Imm10 PF15562.1 ETN98210.1 - 0.072 12.8 3.1 0.31 10.8 2.2 2.0 1 0 0 1 1 1 0 Immunity protein 10 Adipogenin PF15202.1 ETN98210.1 - 0.1 12.4 0.0 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 Adipogenin RHD3 PF05879.7 ETN98212.1 - 7.6e-05 20.8 0.1 7.6e-05 20.8 0.0 1.9 2 1 0 2 2 2 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 ETN98212.1 - 9.3e-05 21.6 0.0 0.00019 20.5 0.0 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 ETN98212.1 - 0.02 14.7 0.1 0.066 13.0 0.0 2.0 2 0 0 2 2 2 0 Dynamin family Kelch_4 PF13418.1 ETN98213.1 - 4e-06 26.4 0.0 0.0044 16.7 0.0 2.2 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETN98213.1 - 0.00033 20.1 0.3 0.016 14.7 0.0 2.2 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.10 ETN98213.1 - 0.00065 19.3 0.7 0.066 13.0 0.0 2.6 2 1 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETN98213.1 - 0.0045 17.1 0.0 1.3 9.2 0.0 2.2 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.1 ETN98213.1 - 0.083 12.8 0.0 5.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.1 ETN98213.1 - 0.15 12.2 0.0 0.72 10.0 0.0 1.9 2 0 0 2 2 2 0 Galactose oxidase, central domain UQ_con PF00179.21 ETN98215.1 - 2.6e-05 23.6 0.2 2.6e-05 23.6 0.2 1.7 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme RWD PF05773.17 ETN98215.1 - 0.0048 16.7 2.2 0.0065 16.3 1.5 1.5 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 ETN98215.1 - 0.033 13.8 0.1 0.06 13.0 0.1 1.6 1 0 0 1 1 1 0 UEV domain BRE PF06113.7 ETN98215.1 - 0.099 11.6 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) Peptidase_C14 PF00656.17 ETN98216.1 - 0.00033 20.4 0.2 0.00041 20.1 0.1 1.1 1 0 0 1 1 1 1 Caspase domain UCH PF00443.24 ETN98216.1 - 0.088 11.9 0.1 0.094 11.8 0.1 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Lysozyme_like PF13702.1 ETN98216.1 - 0.29 10.5 2.0 0.79 9.1 0.1 1.9 1 1 1 2 2 2 0 Lysozyme-like DUF4164 PF13747.1 ETN98217.1 - 0.036 14.1 0.9 0.059 13.4 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Ly49 PF08391.5 ETN98217.1 - 0.089 12.9 7.8 0.11 12.6 5.4 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region ALMT PF11744.3 ETN98217.1 - 0.18 10.4 3.0 0.18 10.3 2.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF641 PF04859.7 ETN98217.1 - 0.22 11.3 7.4 0.25 11.1 5.2 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) HAP1_N PF04849.8 ETN98217.1 - 0.31 9.9 8.4 0.56 9.1 5.7 1.6 1 1 1 2 2 2 0 HAP1 N-terminal conserved region DWNN PF08783.6 ETN98217.1 - 0.52 10.2 5.4 0.6 10.0 2.8 1.9 1 1 1 2 2 2 0 DWNN domain IncA PF04156.9 ETN98217.1 - 1.2 8.7 7.1 1.5 8.3 4.9 1.1 1 0 0 1 1 1 0 IncA protein DUF2681 PF10883.3 ETN98217.1 - 2.4 8.4 11.8 14 5.9 8.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) Bap31 PF05529.7 ETN98217.1 - 7.6 5.9 8.9 11 5.4 6.1 1.3 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like KilA-N PF04383.8 ETN98221.1 - 0.15 11.6 1.8 0.48 10.0 1.2 1.9 1 1 0 1 1 1 0 KilA-N domain DNA_pol_E_B PF04042.11 ETN98221.1 - 0.15 11.2 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B DUF2963 PF11178.3 ETN98221.1 - 5 6.6 7.3 16 4.9 1.5 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2963) Cys_rich_VLP PF14194.1 ETN98222.1 - 4.3 7.1 7.6 0.28 10.9 0.9 2.0 2 0 0 2 2 2 0 Cysteine-rich VLP Copine PF07002.11 ETN98223.1 - 1.8e-12 47.2 1.9 2.8e-12 46.5 1.4 1.3 1 0 0 1 1 1 1 Copine WD40 PF00400.27 ETN98224.1 - 3.5e-06 26.6 7.8 0.016 15.1 0.0 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat HSP90 PF00183.13 ETN98225.1 - 7.1e-51 173.2 11.9 5.8e-35 120.6 0.7 3.3 2 1 1 3 3 3 3 Hsp90 protein HATPase_c_3 PF13589.1 ETN98225.1 - 0.0014 18.2 0.1 0.0034 17.0 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Adeno_E3_15_3 PF03307.9 ETN98225.1 - 0.01 15.5 1.9 0.027 14.2 1.3 1.7 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region HATPase_c PF02518.21 ETN98225.1 - 0.087 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Fe_dep_repr_C PF02742.10 ETN98225.1 - 0.099 12.3 0.1 0.25 11.0 0.1 1.6 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain SAMP PF05924.6 ETN98226.1 - 0.0078 15.3 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 SAMP Motif rve PF00665.21 ETN98228.1 - 0.00093 19.3 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Tox-GHH PF15636.1 ETN98229.1 - 3 7.5 10.5 4 7.1 7.3 1.2 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin YjgP_YjgQ PF03739.9 ETN98230.1 - 0.0079 14.9 1.0 0.0085 14.8 0.7 1.0 1 0 0 1 1 1 1 Predicted permease YjgP/YjgQ family FUSC-like PF12805.2 ETN98230.1 - 0.11 11.3 2.0 0.16 10.8 1.2 1.4 1 1 0 1 1 1 0 FUSC-like inner membrane protein yccS AA_permease_C PF13906.1 ETN98230.1 - 3.5 7.5 7.8 1.7 8.5 2.1 2.5 2 1 0 2 2 2 0 C-terminus of AA_permease DUF3755 PF12579.3 ETN98230.1 - 4.4 6.7 7.9 18 4.7 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3755) Branch PF02485.16 ETN98233.1 - 0.017 14.2 1.2 0.023 13.8 0.8 1.1 1 0 0 1 1 1 0 Core-2/I-Branching enzyme PUB PF09409.5 ETN98233.1 - 0.35 10.6 9.5 0.22 11.3 2.1 3.1 2 1 0 2 2 2 0 PUB domain Phage_GP20 PF06810.6 ETN98234.1 - 0.00037 19.9 16.4 0.00037 19.9 11.3 2.5 2 1 1 3 3 2 1 Phage minor structural protein GP20 Tropomyosin_1 PF12718.2 ETN98234.1 - 0.0022 17.8 21.5 0.15 11.8 7.1 2.5 2 1 1 3 3 2 2 Tropomyosin like PolyA_pol PF01743.15 ETN98234.1 - 0.0099 16.0 0.9 0.014 15.6 0.6 1.3 1 0 0 1 1 1 1 Poly A polymerase head domain AAA_13 PF13166.1 ETN98234.1 - 0.023 13.1 15.7 0.025 13.0 10.9 1.1 1 0 0 1 1 1 0 AAA domain TMF_DNA_bd PF12329.3 ETN98234.1 - 0.06 13.1 23.3 0.47 10.2 12.2 3.1 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TACC PF05010.9 ETN98234.1 - 0.29 10.8 15.7 0.37 10.5 10.9 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) Reo_sigmaC PF04582.7 ETN98234.1 - 0.3 10.2 2.2 0.51 9.4 1.5 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein BRE1 PF08647.6 ETN98234.1 - 0.39 10.7 20.8 0.067 13.1 9.0 2.6 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase DUF342 PF03961.8 ETN98234.1 - 0.42 8.9 14.2 0.46 8.8 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2570 PF10828.3 ETN98234.1 - 0.54 9.8 18.3 0.15 11.6 8.5 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2570) Enkurin PF13864.1 ETN98234.1 - 0.56 10.4 11.8 0.13 12.4 5.6 2.0 2 1 0 2 2 1 0 Calmodulin-binding Seryl_tRNA_N PF02403.17 ETN98234.1 - 0.61 10.1 19.4 0.41 10.6 10.6 2.5 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 PF07926.7 ETN98234.1 - 0.72 9.5 18.3 2.4 7.8 11.3 2.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein USP8_interact PF08941.5 ETN98234.1 - 1.1 8.5 11.3 0.31 10.3 4.6 2.3 1 1 1 2 2 2 0 USP8 interacting DUF972 PF06156.8 ETN98234.1 - 2.2 8.6 18.9 0.2 12.0 7.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Cortex-I_coil PF09304.5 ETN98234.1 - 3.6 7.6 14.5 4.4 7.4 8.9 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil Mgr1 PF08602.5 ETN98234.1 - 4.2 6.2 11.0 2.3 7.1 0.1 2.3 1 1 1 2 2 2 0 Mgr1-like, i-AAA protease complex subunit Laminin_II PF06009.7 ETN98234.1 - 8 6.2 15.0 1.2 8.8 6.7 2.1 1 1 1 2 2 2 0 Laminin Domain II IncA PF04156.9 ETN98234.1 - 9.4 5.7 19.0 26 4.3 13.1 1.8 1 1 1 2 2 2 0 IncA protein DUF747 PF05346.6 ETN98237.1 - 0.0028 16.7 1.6 0.0044 16.1 1.1 1.4 1 1 0 1 1 1 1 Eukaryotic membrane protein family GCC2_GCC3 PF07699.8 ETN98238.1 - 0.059 12.9 0.5 0.081 12.5 0.3 1.2 1 0 0 1 1 1 0 GCC2 and GCC3 CD20 PF04103.10 ETN98238.1 - 0.23 11.4 8.2 0.25 11.2 1.0 1.9 1 1 1 2 2 2 0 CD20-like family Claudin_2 PF13903.1 ETN98238.1 - 9.5 5.8 10.8 14 5.3 7.5 1.4 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Trp_dioxygenase PF03301.8 ETN98239.1 - 0.065 12.3 0.1 0.073 12.1 0.1 1.1 1 0 0 1 1 1 0 Tryptophan 2,3-dioxygenase Peptidase_C14 PF00656.17 ETN98240.1 - 9.3e-10 38.6 0.7 1.4e-09 38.0 0.5 1.3 1 0 0 1 1 1 1 Caspase domain DUF1106 PF06523.6 ETN98240.1 - 0.019 14.8 0.7 0.037 13.8 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1106) DUF1726 PF08351.6 ETN98240.1 - 0.072 12.7 0.2 0.63 9.7 0.0 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF1726) DUF1863 PF08937.6 ETN98240.1 - 0.12 12.3 2.8 5.1 7.1 0.0 2.5 1 1 1 2 2 2 0 MTH538 TIR-like domain (DUF1863) HEAT PF02985.17 ETN98241.1 - 0.00021 21.1 0.0 8.3 6.7 0.0 4.6 5 0 0 5 5 5 2 HEAT repeat iPGM_N PF06415.8 ETN98241.1 - 0.0022 17.3 0.0 0.005 16.2 0.0 1.6 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) DUF573 PF04504.9 ETN98241.1 - 0.021 15.0 6.4 5 7.4 0.0 4.7 4 1 1 5 5 5 0 Protein of unknown function, DUF573 DUF2435 PF10363.4 ETN98241.1 - 0.025 14.4 3.3 1.7 8.6 0.1 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2435) YtzH PF14165.1 ETN98241.1 - 0.16 12.1 9.8 0.64 10.2 0.1 4.1 3 1 1 4 4 4 0 YtzH-like protein BEN PF10523.4 ETN98241.1 - 0.52 10.4 6.7 1.6 8.8 0.1 4.2 4 1 0 4 4 4 0 BEN domain CAP_GLY PF01302.20 ETN98242.1 - 5.7e-13 48.3 0.4 1e-12 47.5 0.3 1.4 1 0 0 1 1 1 1 CAP-Gly domain CZB PF13682.1 ETN98243.1 - 0.018 15.2 0.1 0.039 14.1 0.0 1.6 1 0 0 1 1 1 0 Chemoreceptor zinc-binding domain GatB_Yqey PF02637.13 ETN98243.1 - 0.024 14.3 0.0 0.036 13.7 0.0 1.4 1 1 0 1 1 1 0 GatB domain MIF4G PF02854.14 ETN98245.1 - 7e-10 38.6 2.4 7e-10 38.6 1.6 1.8 2 0 0 2 2 2 1 MIF4G domain YqzH PF14164.1 ETN98245.1 - 0.23 11.4 0.1 0.23 11.4 0.0 3.2 4 0 0 4 4 4 0 YqzH-like protein Atrophin-1 PF03154.10 ETN98245.1 - 0.41 8.7 2.2 0.44 8.6 1.5 1.1 1 0 0 1 1 1 0 Atrophin-1 family DNA_pol_A PF00476.15 ETN98246.1 - 0.012 14.2 1.0 0.016 13.8 0.7 1.1 1 0 0 1 1 1 0 DNA polymerase family A PhyH PF05721.8 ETN98247.1 - 0.1 12.5 0.3 0.13 12.2 0.2 1.1 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) AIG1 PF04548.11 ETN98249.1 - 0.029 13.4 0.6 0.04 13.0 0.4 1.3 1 1 0 1 1 1 0 AIG1 family DUF912 PF06024.7 ETN98250.1 - 0.4 10.7 16.8 0.041 13.9 3.6 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Amnionless PF14828.1 ETN98250.1 - 1.2 7.5 7.3 0.047 12.1 0.3 2.0 1 1 2 3 3 3 0 Amnionless ATP-synt_8 PF00895.15 ETN98250.1 - 7.6 6.8 14.6 2.2 8.5 1.5 3.2 3 0 0 3 3 3 0 ATP synthase protein 8 U-box PF04564.10 ETN98251.1 - 2.9e-14 52.7 0.1 7.4e-14 51.4 0.1 1.7 1 1 0 1 1 1 1 U-box domain zf-Nse PF11789.3 ETN98251.1 - 0.082 12.4 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit NACHT PF05729.7 ETN98252.1 - 0.00017 21.2 0.0 0.00025 20.7 0.0 1.3 1 0 0 1 1 1 1 NACHT domain RNase_Zc3h12a_2 PF14626.1 ETN98252.1 - 0.25 11.1 3.2 0.25 11.1 1.1 1.8 2 1 0 2 2 2 0 Zc3h12a-like Ribonuclease NYN domain RNA_pol_Rpb1_7 PF04990.7 ETN98252.1 - 0.38 10.4 6.1 0.96 9.1 0.3 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 7 RE_HpaII PF09561.5 ETN98253.1 - 0.038 13.1 0.4 0.045 12.9 0.3 1.0 1 0 0 1 1 1 0 HpaII restriction endonuclease GST_N_2 PF13409.1 ETN98253.1 - 0.041 13.8 0.0 0.056 13.4 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Imm24 PF15570.1 ETN98253.1 - 0.14 11.8 1.9 0.16 11.7 1.3 1.2 1 0 0 1 1 1 0 Immunity protein 24 CAP_GLY PF01302.20 ETN98254.1 - 0.00013 21.6 0.0 0.0002 20.9 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Phage_T7_Capsid PF05396.6 ETN98255.1 - 0.0061 16.7 0.0 0.0084 16.2 0.0 1.2 1 0 0 1 1 1 1 Phage T7 capsid assembly protein Mac PF12464.3 ETN98255.1 - 0.076 13.0 0.2 0.21 11.6 0.1 1.9 1 1 0 1 1 1 0 Maltose acetyltransferase Ripply PF14998.1 ETN98256.1 - 0.052 13.6 0.1 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 Transcription Regulator DUF904 PF06005.7 ETN98257.1 - 0.032 14.5 0.2 0.11 12.7 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF904) Gal_mutarotas_2 PF13802.1 ETN98258.1 - 0.043 13.6 0.6 0.091 12.6 0.4 1.5 1 0 0 1 1 1 0 Galactose mutarotase-like PUB PF09409.5 ETN98259.1 - 0.0012 18.5 2.4 0.0039 16.9 1.7 1.8 1 1 0 1 1 1 1 PUB domain Flavi_NS2A PF01005.14 ETN98260.1 - 0.026 13.8 0.5 0.039 13.2 0.4 1.2 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2A L_lactis_ph-MCP PF06673.6 ETN98261.1 - 0.02 13.6 2.7 0.028 13.1 1.9 1.2 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein DUF4071 PF13281.1 ETN98261.1 - 0.16 10.7 15.3 0.18 10.5 10.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4071) ApoO PF09769.4 ETN98261.1 - 0.86 9.2 8.0 3.3 7.4 5.5 2.0 1 1 0 1 1 1 0 Apolipoprotein O DUF3608 PF12257.3 ETN98261.1 - 1.6 7.5 5.4 1.5 7.6 3.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3608) Tropomyosin_1 PF12718.2 ETN98261.1 - 2.5 7.9 40.2 2.5 7.9 8.4 3.1 2 1 1 3 3 3 0 Tropomyosin like CLTH PF10607.4 ETN98262.1 - 0.023 14.3 0.9 0.028 14.0 0.6 1.1 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain DUF562 PF04763.7 ETN98262.1 - 0.055 12.6 0.9 0.51 9.5 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF562) AIG1 PF04548.11 ETN98262.1 - 0.23 10.5 4.5 0.39 9.8 0.0 2.4 2 1 0 2 2 2 0 AIG1 family ABC_tran PF00005.22 ETN98262.1 - 0.35 11.1 1.7 1.3 9.3 0.0 2.1 1 1 1 2 2 2 0 ABC transporter DUF4366 PF14283.1 ETN98262.1 - 0.44 9.9 5.2 0.57 9.5 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF2360 PF10152.4 ETN98262.1 - 0.93 9.7 3.9 0.27 11.5 0.5 1.7 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) KMP11 PF03037.11 ETN98262.1 - 2.3 8.8 11.4 0.14 12.8 2.5 2.0 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 HemX PF04375.9 ETN98262.1 - 3.2 6.2 7.4 4.2 5.8 5.1 1.1 1 0 0 1 1 1 0 HemX DUF641 PF04859.7 ETN98263.1 - 0.17 11.6 3.9 0.24 11.1 2.7 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Bap31 PF05529.7 ETN98263.1 - 1.1 8.7 8.0 0.7 9.3 4.7 1.4 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like FtsL PF04999.8 ETN98263.1 - 2.1 8.1 6.0 5.2 6.8 4.1 1.8 1 1 0 1 1 1 0 Cell division protein FtsL DUF2681 PF10883.3 ETN98263.1 - 3.4 7.9 9.0 7.9 6.7 5.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) Herpes_BLRF2 PF05812.7 ETN98263.1 - 3.5 7.4 7.7 5.5 6.8 5.3 1.3 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein LRR_4 PF12799.2 ETN98264.1 - 3.3e-14 52.1 6.4 8e-05 22.1 1.1 3.6 2 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETN98264.1 - 1.1e-05 25.0 1.4 0.006 16.3 0.7 3.2 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 ETN98264.1 - 0.00044 19.9 8.5 0.27 11.4 0.0 5.2 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.1 ETN98264.1 - 1.3 9.3 0.1 1.3 9.3 0.0 4.0 5 0 0 5 5 5 0 Leucine Rich repeat LRR_7 PF13504.1 ETN98264.1 - 2.5 8.6 5.1 30 5.4 0.0 4.0 4 0 0 4 4 4 0 Leucine rich repeat Antimicrobial12 PF08107.6 ETN98266.1 - 0.29 10.6 0.1 0.29 10.6 0.1 1.9 3 0 0 3 3 3 0 Pleurocidin family EamA PF00892.15 ETN98266.1 - 5.7 6.9 6.2 0.64 10.0 1.4 1.6 2 0 0 2 2 2 0 EamA-like transporter family DUF3819 PF12842.2 ETN98267.1 - 0.099 12.3 0.8 0.13 11.9 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) WD40 PF00400.27 ETN98270.1 - 5.6e-59 194.0 27.7 4.6e-11 42.1 0.3 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETN98270.1 - 3.4e-10 38.7 9.2 0.38 8.8 0.0 6.0 2 2 3 6 6 6 6 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETN98270.1 - 0.019 13.7 8.5 0.6 8.8 0.0 3.6 2 1 1 3 3 3 0 Nup133 N terminal like Kelch_6 PF13964.1 ETN98270.1 - 4.1 7.7 15.3 8.5 6.7 0.2 5.7 6 1 1 7 7 7 0 Kelch motif Ish1 PF10281.4 ETN98271.1 - 0.19 11.8 3.2 4.3 7.5 0.1 3.2 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein TPR_11 PF13414.1 ETN98274.1 - 1.3e-25 88.8 34.0 2.9e-11 42.8 4.8 3.0 1 1 2 3 3 3 3 TPR repeat TPR_12 PF13424.1 ETN98274.1 - 5.5e-25 87.1 10.6 2.8e-11 43.1 0.8 3.0 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETN98274.1 - 6.7e-23 79.2 20.7 1.6e-06 27.4 1.3 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETN98274.1 - 1.8e-18 64.8 14.5 2.6e-06 26.8 0.9 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETN98274.1 - 7.1e-18 62.9 3.6 0.00072 19.1 0.0 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETN98274.1 - 4.5e-17 61.3 7.1 4.7e-07 29.5 0.1 4.0 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETN98274.1 - 2.2e-14 52.0 21.0 4.9e-05 22.8 1.3 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETN98274.1 - 1.5e-10 41.4 1.3 0.00038 21.0 0.0 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETN98274.1 - 1.7e-09 37.5 5.6 0.0049 17.2 0.2 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETN98274.1 - 3.8e-09 36.3 0.0 0.071 13.7 0.0 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 ETN98274.1 - 3.1e-06 27.2 13.0 0.00025 21.1 6.3 3.0 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 ETN98274.1 - 2.3e-05 24.1 15.9 0.34 10.8 0.7 4.1 2 1 1 4 4 4 3 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.4 ETN98274.1 - 5.9e-05 22.2 0.8 0.78 9.0 0.0 3.4 4 0 0 4 4 4 1 SHNi-TPR TPR_19 PF14559.1 ETN98274.1 - 7.9e-05 22.9 4.4 0.033 14.5 0.2 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat SNAP PF14938.1 ETN98274.1 - 0.0001 21.5 8.3 0.0026 16.9 3.9 2.6 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP Sel1 PF08238.7 ETN98274.1 - 0.00067 20.2 6.6 1.1 10.0 0.3 4.1 4 0 0 4 4 4 1 Sel1 repeat TPR_5 PF12688.2 ETN98274.1 - 0.0015 18.5 0.9 0.026 14.5 0.0 2.7 1 1 0 2 2 2 1 Tetratrico peptide repeat DUF627 PF04781.7 ETN98274.1 - 0.0038 16.8 0.5 1.3 8.6 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF627) TPR_3 PF07720.7 ETN98274.1 - 0.005 16.6 2.1 0.005 16.6 1.4 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat KapB PF08810.5 ETN98274.1 - 0.02 14.9 2.0 0.093 12.7 0.5 2.3 1 1 1 2 2 2 0 Kinase associated protein B PPR PF01535.15 ETN98274.1 - 0.029 14.3 0.1 29 4.9 0.0 3.8 4 0 0 4 4 4 0 PPR repeat TPR_17 PF13431.1 ETN98274.1 - 0.059 13.5 21.5 0.68 10.2 0.1 4.5 5 1 0 5 5 4 0 Tetratricopeptide repeat ATP-sulfurylase PF01747.12 ETN98274.1 - 0.067 12.5 0.2 0.087 12.1 0.1 1.2 1 0 0 1 1 1 0 ATP-sulfurylase DUF1178 PF06676.6 ETN98274.1 - 0.12 12.6 0.2 0.15 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) DUF2225 PF09986.4 ETN98274.1 - 0.21 11.0 5.9 1.3 8.4 0.9 2.2 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) SPO22 PF08631.5 ETN98274.1 - 0.27 10.2 2.9 3 6.8 0.5 2.5 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like Fis1_TPR_C PF14853.1 ETN98274.1 - 2.1 8.3 9.0 2.1 8.3 0.9 3.2 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat DUF4099 PF13351.1 ETN98275.1 - 0.0075 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4099) FtsK_SpoIIIE PF01580.13 ETN98275.1 - 0.033 13.6 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family Srg PF02118.16 ETN98275.1 - 0.17 11.3 0.6 0.2 11.0 0.4 1.1 1 0 0 1 1 1 0 Srg family chemoreceptor GWT1 PF06423.7 ETN98277.1 - 0.0013 18.8 6.2 0.0019 18.3 4.3 1.2 1 0 0 1 1 1 1 GWT1 WD40 PF00400.27 ETN98282.1 - 4.2e-48 159.5 22.2 7.5e-13 47.8 0.7 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 ETN98282.1 - 6e-09 34.5 2.3 0.0051 14.9 0.0 4.1 3 1 1 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETN98282.1 - 0.00016 20.5 9.3 0.93 8.1 0.0 4.0 2 2 1 3 3 3 3 Nup133 N terminal like Imm3 PF14425.1 ETN98283.1 - 0.054 13.4 2.3 0.17 11.8 1.6 1.8 1 0 0 1 1 1 0 Immunity protein Imm3 DUF2085 PF09858.4 ETN98285.1 - 0.0094 16.0 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2085) DUF258 PF03193.11 ETN98286.1 - 9.2e-07 28.1 0.4 5.8e-06 25.5 0.3 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 ETN98286.1 - 4.2e-06 26.6 0.6 9.7e-06 25.5 0.2 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.22 ETN98286.1 - 2.7e-05 24.4 0.0 3.3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter Dynamin_N PF00350.18 ETN98286.1 - 5.5e-05 23.0 1.4 0.15 11.8 0.0 2.3 1 1 1 2 2 2 2 Dynamin family AAA_29 PF13555.1 ETN98286.1 - 0.00057 19.3 0.0 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 ETN98286.1 - 0.00078 19.8 0.5 0.0011 19.2 0.4 1.3 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 ETN98286.1 - 0.0044 15.9 0.1 0.0058 15.5 0.1 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.1 ETN98286.1 - 0.0049 16.2 0.1 0.0074 15.7 0.1 1.2 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 ETN98286.1 - 0.0051 17.3 0.2 0.012 16.1 0.1 1.8 2 1 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 ETN98286.1 - 0.0062 16.6 0.0 0.0088 16.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 ETN98286.1 - 0.0064 15.9 0.0 0.0097 15.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Septin PF00735.13 ETN98286.1 - 0.014 14.3 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Septin PduV-EutP PF10662.4 ETN98286.1 - 0.015 14.8 0.1 0.031 13.7 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.15 ETN98286.1 - 0.016 13.9 0.1 0.018 13.7 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit AAA_28 PF13521.1 ETN98286.1 - 0.017 15.0 0.2 0.042 13.8 0.1 1.7 3 0 0 3 3 1 0 AAA domain DUF815 PF05673.8 ETN98286.1 - 0.027 13.4 0.3 0.038 12.9 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF815) SRP54 PF00448.17 ETN98286.1 - 0.043 13.2 0.6 0.15 11.4 0.4 1.9 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain PhoH PF02562.11 ETN98286.1 - 0.044 13.0 0.0 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.1 ETN98286.1 - 0.059 13.2 0.1 0.085 12.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETN98286.1 - 0.062 13.2 0.0 0.072 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain MCM PF00493.18 ETN98286.1 - 0.065 12.0 0.1 0.087 11.6 0.1 1.2 1 0 0 1 1 1 0 MCM2/3/5 family AAA_17 PF13207.1 ETN98286.1 - 0.075 13.8 0.1 0.099 13.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 ETN98286.1 - 0.11 12.0 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 ETN98286.1 - 0.12 11.4 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 Zeta toxin TrwB_AAD_bind PF10412.4 ETN98286.1 - 0.13 10.9 0.2 0.17 10.4 0.1 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.1 ETN98286.1 - 0.25 11.6 2.3 0.77 10.0 0.2 2.1 1 1 1 2 2 2 0 AAA domain Cpn60_TCP1 PF00118.19 ETN98287.1 - 2.6e-05 23.0 0.3 4.3e-05 22.3 0.1 1.5 2 0 0 2 2 2 1 TCP-1/cpn60 chaperonin family DUF975 PF06161.6 ETN98287.1 - 0.00047 19.9 3.5 0.00064 19.5 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF975) DUF3816 PF12822.2 ETN98287.1 - 1.9 8.3 5.9 3.6 7.4 4.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) Myosin_head PF00063.16 ETN98288.1 - 5e-56 190.1 0.0 1.3e-55 188.7 0.0 1.6 1 1 0 1 1 1 1 Myosin head (motor domain) CDC45 PF02724.9 ETN98289.1 - 0.0015 16.6 3.4 0.0018 16.4 2.4 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF1387 PF07139.6 ETN98289.1 - 0.012 15.2 2.5 0.02 14.5 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Zip PF02535.17 ETN98289.1 - 0.1 11.6 0.3 0.12 11.3 0.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Pex14_N PF04695.8 ETN98289.1 - 0.11 12.5 3.9 0.15 12.1 2.7 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pox_Ag35 PF03286.9 ETN98289.1 - 0.15 11.5 8.0 0.2 11.1 5.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Adaptin_binding PF10199.4 ETN98289.1 - 0.16 12.2 18.5 0.38 11.0 12.8 1.5 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Apis_Csd PF11671.3 ETN98289.1 - 0.79 9.5 11.1 1.4 8.7 7.7 1.4 1 0 0 1 1 1 0 Complementary sex determiner protein CobT PF06213.7 ETN98289.1 - 1.1 8.3 14.8 1.4 8.0 10.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RNA_pol_Rpc4 PF05132.9 ETN98289.1 - 1.9 8.4 6.2 3.4 7.6 4.3 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Menin PF05053.8 ETN98289.1 - 2.1 6.4 9.3 2.8 6.0 6.5 1.1 1 0 0 1 1 1 0 Menin NOA36 PF06524.7 ETN98289.1 - 2.9 7.0 11.5 3.9 6.6 7.9 1.2 1 0 0 1 1 1 0 NOA36 protein Translin PF01997.11 ETN98290.1 - 0.033 13.8 0.1 2.2 7.8 0.0 2.2 1 1 1 2 2 2 0 Translin family Cpn60_TCP1 PF00118.19 ETN98291.1 - 1.3e-16 60.3 0.4 6e-16 58.1 0.3 1.8 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family AP4E_app_platf PF14807.1 ETN98294.1 - 0.015 15.5 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform DUF1390 PF07150.6 ETN98294.1 - 9.1 5.5 10.0 13 5.0 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) Ppx-GppA PF02541.11 ETN98295.1 - 1.6e-11 43.9 0.1 2.4e-11 43.3 0.0 1.4 2 0 0 2 2 2 1 Ppx/GppA phosphatase family MMR_HSR1 PF01926.18 ETN98296.1 - 4.4e-20 71.7 0.0 9e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETN98296.1 - 3.1e-11 42.7 0.1 4.6e-11 42.2 0.1 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 ETN98296.1 - 3.4e-07 29.8 0.4 7.5e-05 22.2 0.3 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 ETN98296.1 - 5.5e-06 25.6 0.0 1.3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 ETN98296.1 - 1.1e-05 24.5 2.4 0.00075 18.5 1.7 2.9 2 1 0 2 2 2 1 Septin Dynamin_N PF00350.18 ETN98296.1 - 4.9e-05 23.2 0.1 0.1 12.4 0.1 2.6 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 ETN98296.1 - 0.0038 17.7 0.0 0.0091 16.4 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein IIGP PF05049.8 ETN98296.1 - 0.009 14.8 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.1 ETN98296.1 - 0.016 15.3 0.2 0.069 13.2 0.0 2.1 2 1 0 2 2 2 0 AAA domain DUF4020 PF13212.1 ETN98296.1 - 0.017 14.7 1.4 1.7 8.1 0.0 3.1 2 2 1 3 3 3 0 Domain of unknown function (DUF4020) SRPRB PF09439.5 ETN98296.1 - 0.034 13.3 0.1 0.085 12.0 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 ETN98296.1 - 0.037 13.5 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AIG1 PF04548.11 ETN98296.1 - 0.044 12.8 0.1 0.077 12.0 0.0 1.3 1 0 0 1 1 1 0 AIG1 family MobB PF03205.9 ETN98296.1 - 0.054 13.2 0.0 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 ETN98296.1 - 0.062 14.1 0.0 0.33 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Secretin_N_2 PF07655.8 ETN98297.1 - 5.4e-07 29.9 8.8 1.1e-06 28.9 6.1 1.5 1 0 0 1 1 1 1 Secretin N-terminal domain Secretin PF00263.16 ETN98297.1 - 5.9e-06 25.7 0.5 5.9e-06 25.7 0.3 2.1 3 1 0 3 3 3 1 Bacterial type II and III secretion system protein STN PF07660.9 ETN98297.1 - 0.051 13.1 0.1 1.4 8.5 0.0 2.6 1 1 1 2 2 2 0 Secretin and TonB N terminus short domain HTH_Tnp_Tc3_2 PF01498.13 ETN98299.1 - 7e-09 35.6 0.2 1.6e-08 34.4 0.1 1.6 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.1 ETN98299.1 - 8.4e-08 32.0 0.0 1.1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease PX PF00787.19 ETN98300.1 - 3.1e-13 49.4 0.5 7.5e-13 48.2 0.4 1.6 1 0 0 1 1 1 1 PX domain AP-5_subunit_s1 PF15001.1 ETN98301.1 - 0.00019 21.4 1.6 0.00025 21.0 1.1 1.1 1 0 0 1 1 1 1 AP-5 complex subunit sigma-1 UPF0172 PF03665.8 ETN98301.1 - 0.088 12.2 3.1 0.1 12.1 2.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) FPN1 PF06963.7 ETN98301.1 - 0.18 10.1 0.7 0.22 9.8 0.5 1.0 1 0 0 1 1 1 0 Ferroportin1 (FPN1) TIP120 PF08623.5 ETN98302.1 - 4.9e-05 22.9 0.8 0.23 11.0 0.0 2.7 1 1 2 3 3 3 3 TATA-binding protein interacting (TIP20) HEAT PF02985.17 ETN98302.1 - 0.00011 22.0 0.1 5.3 7.4 0.0 3.3 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 ETN98302.1 - 0.00051 20.2 0.0 0.0021 18.2 0.0 1.9 1 1 0 1 1 1 1 HEAT repeats Cnd1 PF12717.2 ETN98302.1 - 0.00071 19.4 0.1 0.0008 19.2 0.1 1.1 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 ETN98302.1 - 0.0069 16.2 0.0 0.034 14.0 0.0 1.9 1 1 1 2 2 2 2 Protein of unknown function (DUF2435) HNH_5 PF14279.1 ETN98302.1 - 0.011 15.7 0.2 2.2 8.3 0.0 2.3 1 1 1 2 2 2 0 HNH endonuclease Vac14_Fab1_bd PF12755.2 ETN98302.1 - 0.012 15.9 0.2 0.19 12.1 0.0 2.2 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region MOR2-PAG1_C PF14225.1 ETN98302.1 - 0.04 13.6 0.1 0.1 12.3 0.0 1.5 1 1 1 2 2 2 0 Cell morphogenesis C-terminal Yippee-Mis18 PF03226.9 ETN98302.1 - 0.63 10.1 3.5 0.19 11.8 0.5 1.7 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TPR_12 PF13424.1 ETN98303.1 - 1.1e-73 243.1 22.2 5.1e-17 61.5 0.7 5.7 3 1 2 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETN98303.1 - 1.7e-43 145.3 0.0 1.9e-06 27.5 0.0 7.8 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETN98303.1 - 1.2e-36 122.8 43.4 5e-08 32.2 0.7 8.6 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_7 PF13176.1 ETN98303.1 - 6e-34 113.1 15.8 5.1e-06 25.8 0.0 7.8 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_11 PF13414.1 ETN98303.1 - 3.3e-33 113.1 24.9 1.4e-09 37.4 2.5 5.6 5 1 0 5 5 5 4 TPR repeat TPR_2 PF07719.12 ETN98303.1 - 6.3e-26 88.1 33.9 1.4e-07 30.8 0.6 8.4 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.1 ETN98303.1 - 8e-21 72.2 47.3 2.1e-06 27.1 2.2 8.6 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 ETN98303.1 - 9.3e-15 54.8 2.2 0.033 14.8 0.0 6.2 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 ETN98303.1 - 1.1e-12 47.0 12.2 0.2 11.9 0.0 7.7 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_6 PF13174.1 ETN98303.1 - 4.4e-11 42.4 8.5 0.0067 16.8 0.0 6.7 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETN98303.1 - 6.3e-09 35.6 0.8 0.6 10.9 0.0 6.8 6 2 2 8 8 8 1 Tetratricopeptide repeat Apc3 PF12895.2 ETN98303.1 - 1.5e-06 28.2 19.2 0.033 14.3 1.7 5.0 2 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 ETN98303.1 - 0.00063 19.4 31.0 1.6 8.6 0.2 7.1 8 0 0 8 8 8 3 Tetratricopeptide repeat Alpha-amylase_N PF02903.9 ETN98303.1 - 0.0074 16.2 10.1 7.3 6.5 0.1 4.8 1 1 4 5 5 5 2 Alpha amylase, N-terminal ig-like domain PPR PF01535.15 ETN98303.1 - 0.41 10.7 8.1 4.2 7.5 0.1 5.2 5 0 0 5 5 5 0 PPR repeat NACHT PF05729.7 ETN98305.1 - 0.00028 20.5 0.0 0.0006 19.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Pentapeptide PF00805.17 ETN98305.1 - 0.013 14.7 0.1 0.027 13.7 0.1 1.5 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) AAA_18 PF13238.1 ETN98305.1 - 0.02 15.1 1.1 0.084 13.1 0.1 2.7 2 0 0 2 2 2 0 AAA domain Zn-ribbon_8 PF09723.5 ETN98305.1 - 0.049 13.5 0.6 0.27 11.2 0.0 2.5 2 0 0 2 2 2 0 Zinc ribbon domain PDCD9 PF07147.7 ETN98306.1 - 0.024 13.4 0.1 0.024 13.4 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S30 (PDCD9) CUE PF02845.11 ETN98306.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 CUE domain DUF441 PF04284.8 ETN98306.1 - 0.16 11.8 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF441) WBS_methylT PF12589.3 ETN98306.1 - 1 9.8 6.5 0.92 10.0 3.4 1.7 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome RRM_1 PF00076.17 ETN98307.1 - 1.3e-21 75.9 0.0 3.1e-09 36.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETN98307.1 - 2.5e-15 56.2 0.0 5.3e-09 35.9 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETN98307.1 - 3.8e-11 42.6 0.1 0.0031 17.3 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phycobilisome PF00502.14 ETN98307.1 - 0.059 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Phycobilisome protein SNF2_assoc PF08455.5 ETN98308.1 - 0.0059 15.2 0.3 0.0071 14.9 0.2 1.0 1 0 0 1 1 1 1 Bacterial SNF2 helicase associated tRNA-synt_1g PF09334.6 ETN98309.1 - 0.048 12.3 2.0 0.077 11.6 1.4 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) CTDII PF01556.13 ETN98310.1 - 3.3e-18 65.3 0.2 6.2e-14 51.6 0.0 2.2 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 ETN98310.1 - 0.063 13.3 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 DnaJ central domain Dus PF01207.12 ETN98311.1 - 1.9e-07 30.2 0.0 2.4e-07 29.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DEAD PF00270.24 ETN98313.1 - 3.7e-31 107.8 1.3 8.2e-29 100.2 0.2 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 ETN98313.1 - 1.1e-17 63.6 0.1 3.3e-17 62.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETN98313.1 - 0.0031 17.3 0.3 0.012 15.5 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit F-box PF00646.28 ETN98314.1 - 0.0065 16.1 0.2 0.018 14.6 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 ETN98314.1 - 0.02 14.6 0.4 0.062 13.0 0.0 2.0 2 0 0 2 2 2 0 F-box-like DUF2939 PF11159.3 ETN98314.1 - 0.14 12.3 0.2 0.9 9.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) WD40 PF00400.27 ETN98315.1 - 9.3e-27 91.9 7.7 1.9e-10 40.2 0.0 4.4 4 1 0 4 4 4 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETN98315.1 - 0.00077 18.3 0.5 0.0011 17.8 0.4 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nup160 PF11715.3 ETN98315.1 - 0.018 13.1 0.1 0.44 8.6 0.0 2.2 1 1 1 2 2 2 0 Nucleoporin Nup120/160 TetM_leader PF08076.6 ETN98315.1 - 0.34 10.4 2.5 0.92 9.1 0.2 2.4 2 0 0 2 2 2 0 Tetracycline resistance determinant leader peptide zf-C3HC4_2 PF13923.1 ETN98316.1 - 0.088 12.8 4.4 2.3 8.2 2.9 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF1654 PF07867.6 ETN98317.1 - 0.05 12.9 0.1 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) Spindle_Spc25 PF08234.7 ETN98317.1 - 0.061 13.3 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 Chromosome segregation protein Spc25 GP120 PF00516.13 ETN98318.1 - 0.082 11.1 4.0 0.083 11.1 2.8 1.0 1 0 0 1 1 1 0 Envelope glycoprotein GP120 DUF4468 PF14730.1 ETN98318.1 - 0.4 10.3 3.6 3.4 7.4 0.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4468) with TBP-like fold Atrophin-1 PF03154.10 ETN98319.1 - 8 4.4 8.1 10 4.0 5.6 1.1 1 0 0 1 1 1 0 Atrophin-1 family Fis1_TPR_C PF14853.1 ETN98320.1 - 0.028 14.2 0.3 0.047 13.5 0.2 1.3 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat F-112 PF09645.5 ETN98321.1 - 0.0065 16.3 1.4 0.0065 16.3 1.0 1.6 2 0 0 2 2 2 1 F-112 protein Exo_endo_phos_2 PF14529.1 ETN98322.1 - 0.0027 17.3 0.5 0.006 16.1 0.4 1.7 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase PseudoU_synth_2 PF00849.17 ETN98323.1 - 0.017 14.9 0.2 0.023 14.5 0.1 1.1 1 0 0 1 1 1 0 RNA pseudouridylate synthase MFS_1 PF07690.11 ETN98325.1 - 6.2e-24 84.3 13.7 7.3e-24 84.1 9.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETN98325.1 - 7.4e-09 34.6 7.6 9.8e-09 34.2 5.1 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 ETN98325.1 - 0.016 13.3 7.0 0.019 13.0 4.8 1.0 1 0 0 1 1 1 0 Transmembrane secretion effector UNC-93 PF05978.11 ETN98325.1 - 0.11 12.0 1.3 0.14 11.6 0.9 1.2 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 SAM_2 PF07647.12 ETN98326.1 - 1.8e-08 34.1 0.3 2.5e-08 33.6 0.2 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETN98326.1 - 1e-07 31.9 2.4 2.1e-07 30.9 1.7 1.5 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 ETN98326.1 - 0.058 13.1 2.3 0.18 11.5 1.6 1.8 1 1 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Dendrin PF15498.1 ETN98326.1 - 0.19 10.1 1.2 0.25 9.8 0.9 1.0 1 0 0 1 1 1 0 Nephrin and CD2AP-binding protein, Dendrin Myb_DNA-bind_3 PF12776.2 ETN98327.1 - 1.9 9.1 8.1 0.25 11.9 0.8 2.1 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain DUF342 PF03961.8 ETN98327.1 - 7.4 4.8 9.3 8.5 4.6 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3487 PF11990.3 ETN98328.1 - 1.7 8.0 11.4 0.042 13.2 2.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) Herpes_UL25 PF01499.11 ETN98332.1 - 4.5 5.4 15.6 8.8 4.5 10.8 1.5 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF1912 PF08930.5 ETN98333.1 - 0.56 10.3 3.5 0.86 9.7 1.9 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1912) WD40 PF00400.27 ETN98334.1 - 4.5e-73 238.7 19.1 1.1e-10 40.9 0.5 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETN98334.1 - 2.1e-05 22.8 15.4 0.21 9.6 0.2 4.8 2 1 3 5 5 5 4 Nucleoporin Nup120/160 DUF1258 PF06869.7 ETN98334.1 - 0.00085 18.4 2.8 1.5 7.8 0.1 4.1 2 1 2 4 4 4 1 Protein of unknown function (DUF1258) L-fibroin PF05849.6 ETN98334.1 - 0.00086 18.7 0.2 0.0021 17.4 0.1 1.6 1 0 0 1 1 1 1 Fibroin light chain (L-fibroin) PQQ_2 PF13360.1 ETN98334.1 - 0.013 14.9 0.0 0.047 13.1 0.0 1.9 1 1 0 1 1 1 0 PQQ-like domain PD40 PF07676.7 ETN98334.1 - 0.15 11.7 3.7 26 4.6 0.0 4.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF4306 PF14154.1 ETN98334.1 - 0.2 11.6 1.9 4.1 7.4 0.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4306) PT PF04886.7 ETN98335.1 - 0.2 10.9 49.4 0.035 13.4 19.0 3.7 2 1 0 2 2 2 0 PT repeat ORC6 PF05460.8 ETN98335.1 - 0.22 10.5 5.9 0.38 9.8 4.1 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF4106 PF13388.1 ETN98335.1 - 6.7 5.5 6.4 13 4.6 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DUF1623 PF07785.6 ETN98336.1 - 0.0093 15.8 0.4 0.015 15.2 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1623) Cpn60_TCP1 PF00118.19 ETN98337.1 - 6.7e-15 54.6 0.1 6.8e-15 54.6 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NIT PF08376.5 ETN98337.1 - 0.017 14.6 0.0 0.59 9.5 0.0 2.0 2 0 0 2 2 2 0 Nitrate and nitrite sensing ChlI PF13541.1 ETN98337.1 - 0.03 13.8 0.1 0.047 13.2 0.1 1.3 1 0 0 1 1 1 0 Subunit ChlI of Mg-chelatase Phe_tRNA-synt_N PF02912.13 ETN98337.1 - 0.12 12.1 1.1 0.44 10.2 0.2 2.0 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain DUF2493 PF10686.4 ETN98337.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2493) LXG PF04740.7 ETN98339.1 - 0.0055 16.5 15.8 0.0055 16.5 11.0 1.7 1 1 0 1 1 1 1 LXG domain of WXG superfamily YqzE PF14038.1 ETN98339.1 - 0.55 10.0 3.9 1.2 8.9 2.7 1.6 1 0 0 1 1 1 0 YqzE-like protein ALMT PF11744.3 ETN98339.1 - 0.76 8.3 8.2 1.1 7.9 5.5 1.3 1 1 0 1 1 1 0 Aluminium activated malate transporter DUF745 PF05335.8 ETN98339.1 - 1.2 8.5 9.7 0.73 9.3 5.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF745) GspL_C PF12693.2 ETN98339.1 - 1.8 8.2 9.0 0.71 9.6 4.0 1.7 2 0 0 2 2 2 0 GspL periplasmic domain ABC2_membrane_3 PF12698.2 ETN98339.1 - 2.1 7.3 6.3 2.4 7.0 4.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF651 PF04895.7 ETN98339.1 - 3.1 7.4 6.4 7 6.3 0.9 2.2 2 0 0 2 2 2 0 Archaeal protein of unknown function (DUF651) BAAT_C PF08840.6 ETN98339.1 - 7.4 6.2 8.1 2.2 7.9 1.3 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Kelch_6 PF13964.1 ETN98340.1 - 4.7e-10 39.1 6.4 0.00029 20.8 0.1 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 ETN98340.1 - 4.8e-05 22.8 4.2 0.0026 17.2 0.1 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETN98340.1 - 9.4e-05 22.1 1.6 0.14 11.9 0.0 3.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETN98340.1 - 0.0042 17.2 0.2 4.7 7.4 0.0 3.0 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETN98340.1 - 0.0047 16.8 2.6 1.6 8.7 0.0 3.9 4 0 0 4 4 4 2 Kelch motif tRNA-synt_1b PF00579.20 ETN98341.1 - 7.2e-42 143.4 0.3 9.4e-42 143.1 0.0 1.3 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) Peptidase_A4 PF01828.12 ETN98341.1 - 0.053 12.5 0.1 0.085 11.8 0.1 1.2 1 0 0 1 1 1 0 Peptidase A4 family PHB_acc PF05233.8 ETN98341.1 - 0.14 11.8 0.2 1.5 8.6 0.1 2.3 2 0 0 2 2 2 0 PHB accumulation regulatory domain zf-RING_2 PF13639.1 ETN98342.1 - 2.4e-13 49.6 8.1 2.4e-13 49.6 5.6 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 ETN98342.1 - 2.6e-05 23.8 3.8 2.6e-05 23.8 2.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETN98342.1 - 3.2e-05 23.5 4.3 3.2e-05 23.5 3.0 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 ETN98342.1 - 7.5e-05 22.6 6.9 7.5e-05 22.6 4.8 2.0 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETN98342.1 - 9.4e-05 22.4 7.8 9.4e-05 22.4 5.4 2.2 1 1 1 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 ETN98342.1 - 0.00028 20.4 3.2 0.00028 20.4 2.2 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF1510 PF07423.6 ETN98342.1 - 0.0016 17.8 0.4 0.0021 17.4 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) RLL PF10036.4 ETN98342.1 - 0.0066 15.9 0.5 0.0087 15.5 0.3 1.1 1 0 0 1 1 1 1 Putative carnitine deficiency-associated protein Peptidase_S49_N PF08496.5 ETN98342.1 - 0.07 12.9 0.6 0.11 12.2 0.4 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Neur_chan_memb PF02932.11 ETN98342.1 - 0.09 12.6 1.6 0.21 11.4 1.2 1.3 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Prok-RING_4 PF14447.1 ETN98342.1 - 0.28 10.7 4.7 1.8 8.1 3.2 2.3 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 CENP-B_dimeris PF09026.5 ETN98342.1 - 0.32 11.2 2.0 1 9.6 1.6 1.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF4407 PF14362.1 ETN98343.1 - 0.033 13.1 20.6 0.038 12.9 14.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Osmo_CC PF08946.5 ETN98343.1 - 0.18 11.8 6.8 0.17 11.9 1.4 3.0 2 1 1 3 3 3 0 Osmosensory transporter coiled coil Synaptobrevin PF00957.16 ETN98343.1 - 0.9 9.1 4.9 2.7 7.6 3.4 2.0 1 1 0 1 1 1 0 Synaptobrevin CENP-Q PF13094.1 ETN98343.1 - 0.98 9.4 27.5 0.033 14.2 12.4 2.4 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1675 PF07897.6 ETN98343.1 - 1.8 8.3 18.5 2 8.2 12.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF2347 PF09804.4 ETN98343.1 - 3.4 6.8 6.7 2.1 7.5 3.7 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Syntaxin PF00804.20 ETN98343.1 - 5.9 7.1 17.4 11 6.2 11.4 2.1 1 1 0 1 1 1 0 Syntaxin Adeno_PIX PF03955.9 ETN98343.1 - 6.1 7.4 8.5 1.5 9.3 0.8 2.2 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Fib_alpha PF08702.5 ETN98343.1 - 6.2 6.9 20.8 0.94 9.5 5.4 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Exo_endo_phos_2 PF14529.1 ETN98344.1 - 4.9e-05 22.9 0.6 0.00011 21.7 0.2 1.7 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase zf-RVT PF13966.1 ETN98344.1 - 0.0045 17.2 0.4 0.0086 16.3 0.3 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF1048 PF06304.6 ETN98345.1 - 0.00012 22.3 0.1 0.00021 21.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1048) WSS_VP PF12175.3 ETN98345.1 - 0.21 10.6 4.5 0.48 9.4 0.9 2.1 2 0 0 2 2 2 0 White spot syndrome virus structural envelope protein VP Suppressor_APC PF11414.3 ETN98345.1 - 0.38 10.5 3.3 0.38 10.5 0.8 2.3 2 1 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein GalP_UDP_tr_C PF02744.12 ETN98346.1 - 0.089 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain Dsl1_C PF11989.3 ETN98346.1 - 0.26 10.4 5.0 0.29 10.2 3.4 1.0 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 C terminal zf-CCHC PF00098.18 ETN98347.1 - 0.1 12.5 1.9 0.23 11.4 1.3 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF912 PF06024.7 ETN98347.1 - 0.88 9.6 3.5 1.8 8.6 2.4 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3642 PF12182.3 ETN98348.1 - 0.13 12.7 1.0 20 5.7 0.1 2.6 2 0 0 2 2 2 0 Bacterial lipoprotein EAP30 PF04157.11 ETN98349.1 - 0.024 13.8 1.5 0.033 13.3 1.0 1.3 1 0 0 1 1 1 0 EAP30/Vps36 family Plasmid_RAQPRD PF09686.5 ETN98349.1 - 0.14 12.2 2.4 0.35 10.9 0.2 2.2 1 1 1 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Peptidase_S49_N PF08496.5 ETN98349.1 - 5.1 6.8 8.9 3.9 7.2 2.8 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal AAA_16 PF13191.1 ETN98350.1 - 9.2e-05 22.5 0.0 0.00031 20.7 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 ETN98350.1 - 0.00018 21.6 0.1 0.00077 19.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.1 ETN98350.1 - 0.0029 17.2 0.4 0.64 9.5 0.1 2.5 3 0 0 3 3 3 2 AAA domain TACC PF05010.9 ETN98350.1 - 0.012 15.4 0.0 0.036 13.8 0.0 1.7 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) IstB_IS21 PF01695.12 ETN98350.1 - 0.021 14.2 0.0 0.18 11.2 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.1 ETN98350.1 - 0.082 13.7 1.0 0.22 12.3 0.2 2.2 2 1 0 2 2 2 0 AAA domain DUF1542 PF07564.6 ETN98350.1 - 0.11 12.5 0.5 0.3 11.1 0.1 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) RNA_helicase PF00910.17 ETN98350.1 - 0.24 11.6 2.9 0.72 10.0 0.4 3.1 2 2 2 4 4 4 0 RNA helicase DUF87 PF01935.12 ETN98350.1 - 1.8 8.3 6.2 1.9 8.2 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function DUF87 DUF4422 PF14393.1 ETN98351.1 - 0.023 14.3 0.1 0.035 13.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4422) NACHT PF05729.7 ETN98352.1 - 0.025 14.2 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 NACHT domain CAF-1_p150 PF11600.3 ETN98353.1 - 0.24 10.7 25.0 0.32 10.3 17.3 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CENP-T PF15511.1 ETN98353.1 - 2 7.5 18.6 2.5 7.2 12.9 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Peptidase_S64 PF08192.6 ETN98353.1 - 8.3 4.5 19.3 11 4.2 13.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 FA_desaturase PF00487.19 ETN98354.1 - 0.03 13.7 0.1 0.035 13.5 0.1 1.1 1 0 0 1 1 1 0 Fatty acid desaturase FANCI_HD1 PF14679.1 ETN98354.1 - 0.033 13.9 1.0 0.072 12.8 0.1 1.8 2 0 0 2 2 2 0 FANCI helical domain 1 DUF829 PF05705.9 ETN98354.1 - 0.041 13.5 0.0 0.35 10.5 0.0 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Cys_rich_VLP PF14194.1 ETN98355.1 - 0.047 13.4 0.2 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 Cysteine-rich VLP DUF3344 PF11824.3 ETN98356.1 - 0.066 12.5 0.6 0.44 9.8 0.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3344) Herpes_TK_C PF08465.5 ETN98356.1 - 0.067 12.7 0.2 0.22 11.0 0.1 1.9 1 0 0 1 1 1 0 Thymidine kinase from Herpesvirus C-terminal Cobl PF09469.5 ETN98356.1 - 0.068 13.1 0.3 5.5 7.0 0.2 2.3 1 1 1 2 2 2 0 Cordon-bleu ubiquitin-like domain RicinB_lectin_2 PF14200.1 ETN98357.1 - 0.019 15.3 0.0 0.08 13.3 0.0 2.1 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like DUF3396 PF11876.3 ETN98357.1 - 0.13 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3396) WD40 PF00400.27 ETN98358.1 - 9.2e-84 272.6 28.6 3e-14 52.2 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETN98358.1 - 8.4e-07 27.4 7.0 0.71 7.9 0.0 5.6 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETN98358.1 - 2.2e-06 26.2 0.6 0.01 14.1 0.0 2.8 2 1 1 3 3 3 3 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETN98358.1 - 2.7e-05 23.1 12.8 0.66 8.6 2.6 4.6 1 1 3 4 4 4 4 Nup133 N terminal like PQQ_2 PF13360.1 ETN98358.1 - 3e-05 23.6 0.0 0.024 14.1 0.0 3.0 2 1 1 3 3 3 2 PQQ-like domain Resistin PF06954.6 ETN98358.1 - 5.7e-05 23.3 1.5 0.39 11.0 0.0 4.1 3 1 1 4 4 4 1 Resistin DUF4221 PF13970.1 ETN98358.1 - 0.00051 19.4 2.5 1.9 7.7 0.0 4.4 1 1 4 5 5 5 1 Domain of unknown function (DUF4221) NUMOD4 PF07463.6 ETN98358.1 - 0.013 15.3 0.2 0.84 9.5 0.0 3.5 3 0 0 3 3 3 0 NUMOD4 motif DUF727 PF05303.7 ETN98358.1 - 0.063 13.0 0.1 4.3 7.1 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF727) NHL PF01436.16 ETN98358.1 - 0.1 12.6 0.4 12 6.0 0.0 3.8 4 0 0 4 4 4 0 NHL repeat DUF2415 PF10313.4 ETN98358.1 - 0.12 12.0 1.7 3.7 7.2 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) Pkinase PF00069.20 ETN98359.1 - 4.3e-58 196.5 0.2 5.2e-58 196.2 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETN98359.1 - 6.3e-34 117.2 0.1 7.7e-34 116.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 ETN98359.1 - 2.2e-06 27.1 0.2 3.2e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 ETN98359.1 - 0.00016 20.7 0.1 0.00073 18.5 0.0 1.8 1 1 1 2 2 2 1 Kinase-like YukC PF10140.4 ETN98359.1 - 0.00067 18.3 0.2 0.00088 17.9 0.1 1.0 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 ETN98359.1 - 0.0027 17.4 0.2 0.03 14.0 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 ETN98359.1 - 0.0038 16.3 0.1 0.0055 15.7 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 ETN98359.1 - 0.0085 15.4 0.2 0.014 14.7 0.1 1.3 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 ETN98359.1 - 0.046 13.2 0.4 0.086 12.4 0.3 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase Pept_tRNA_hydro PF01195.14 ETN98359.1 - 0.096 12.1 0.1 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase DUF4519 PF15012.1 ETN98360.1 - 4.5 7.2 10.8 5.4 7.0 0.4 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) CALCOCO1 PF07888.6 ETN98361.1 - 0.044 12.0 22.8 0.011 14.0 5.1 2.2 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Reo_sigmaC PF04582.7 ETN98361.1 - 0.1 11.7 3.3 0.93 8.6 1.0 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein USP8_interact PF08941.5 ETN98361.1 - 1.2 8.3 7.8 3 7.1 1.1 2.7 2 0 0 2 2 2 0 USP8 interacting DUF848 PF05852.6 ETN98361.1 - 1.9 8.3 21.9 4.2 7.2 3.0 3.1 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Prp19 PF08606.6 ETN98361.1 - 4.9 6.9 10.2 15 5.3 0.1 3.0 3 0 0 3 3 3 0 Prp19/Pso4-like DUF972 PF06156.8 ETN98361.1 - 6 7.2 32.5 1.4 9.2 5.1 4.1 3 1 0 3 3 3 0 Protein of unknown function (DUF972) TLD PF07534.11 ETN98362.1 - 9.3e-13 48.3 0.1 2.3e-12 47.0 0.1 1.7 1 0 0 1 1 1 1 TLD Acid_PPase PF12689.2 ETN98362.1 - 0.011 15.3 4.4 0.043 13.4 3.0 2.0 1 1 0 1 1 1 0 Acid Phosphatase CH PF00307.26 ETN98362.1 - 0.28 11.2 2.3 0.49 10.4 0.3 2.2 2 0 0 2 2 2 0 Calponin homology (CH) domain VIT1 PF01988.14 ETN98363.1 - 0.014 14.9 0.8 0.12 11.7 0.0 2.1 2 0 0 2 2 2 0 VIT family BAF1_ABF1 PF04684.8 ETN98363.1 - 0.035 12.9 10.7 0.044 12.6 7.4 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TEP1_N PF05386.6 ETN98363.1 - 0.1 12.0 0.3 0.21 11.0 0.2 1.5 1 0 0 1 1 1 0 TEP1 N-terminal domain Nicastrin PF05450.10 ETN98363.1 - 0.23 10.6 3.3 0.41 9.8 2.3 1.3 1 0 0 1 1 1 0 Nicastrin DUF533 PF04391.7 ETN98363.1 - 0.37 10.1 9.2 7 5.9 6.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF533) Activator_LAG-3 PF11498.3 ETN98363.1 - 0.43 9.2 23.4 0.71 8.5 16.2 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF2855 PF11017.3 ETN98363.1 - 0.52 9.3 5.7 1.7 7.6 1.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2855) PAT1 PF09770.4 ETN98363.1 - 0.92 7.6 24.0 1.1 7.3 16.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LIM_bind PF01803.11 ETN98363.1 - 0.93 8.5 11.1 4 6.4 5.7 2.1 2 0 0 2 2 2 0 LIM-domain binding protein FimP PF09766.4 ETN98363.1 - 3.1 6.7 19.3 0.081 11.9 8.9 1.5 2 0 0 2 2 2 0 Fms-interacting protein DUF4557 PF15101.1 ETN98363.1 - 5.4 6.8 12.6 1.1 9.0 6.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) DUF4162 PF13732.1 ETN98364.1 - 0.029 14.8 0.8 0.67 10.4 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4162) Metallophos_2 PF12850.2 ETN98365.1 - 1.5e-09 37.8 0.0 2.6e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 ETN98365.1 - 1.6e-09 37.4 6.0 8.2e-09 35.1 4.2 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase YolD PF08863.5 ETN98365.1 - 0.0073 16.1 0.2 0.12 12.1 0.0 2.3 2 0 0 2 2 2 1 YolD-like protein Ecm33 PF12454.3 ETN98370.1 - 0.044 13.6 0.1 0.14 12.0 0.1 1.9 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Spc24 PF08286.6 ETN98371.1 - 0.18 11.5 4.3 0.24 11.0 3.0 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Peptidase_S49_N PF08496.5 ETN98372.1 - 0.00079 19.2 6.1 0.001 18.9 4.2 1.1 1 0 0 1 1 1 1 Peptidase family S49 N-terminal GAGA_bind PF06217.7 ETN98372.1 - 0.062 13.2 10.5 0.074 13.0 7.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Chromo PF00385.19 ETN98372.1 - 0.064 12.9 0.2 0.064 12.9 0.1 2.0 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain DUF4614 PF15391.1 ETN98372.1 - 0.072 12.8 5.0 0.094 12.4 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF3807 PF12720.2 ETN98372.1 - 0.16 12.1 11.4 0.26 11.4 7.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) CDC45 PF02724.9 ETN98372.1 - 0.17 9.9 4.0 0.16 9.9 2.8 1.1 1 0 0 1 1 1 0 CDC45-like protein RP-C_C PF11800.3 ETN98372.1 - 0.17 11.5 5.0 0.18 11.4 3.5 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF1510 PF07423.6 ETN98372.1 - 0.17 11.2 12.6 0.26 10.6 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Zip PF02535.17 ETN98372.1 - 0.31 9.9 1.8 0.35 9.8 1.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Mem_trans PF03547.13 ETN98372.1 - 0.41 8.8 2.4 0.45 8.7 1.6 1.1 1 0 0 1 1 1 0 Membrane transport protein FAM176 PF14851.1 ETN98372.1 - 0.78 9.4 7.1 11 5.6 1.6 2.2 1 1 1 2 2 2 0 FAM176 family DUF3260 PF11658.3 ETN98372.1 - 0.85 7.6 3.6 1.1 7.3 2.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3260) Neur_chan_memb PF02932.11 ETN98372.1 - 0.94 9.3 4.5 1 9.2 3.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4551 PF15087.1 ETN98372.1 - 1.5 7.1 6.6 1.6 6.9 4.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Serinc PF03348.10 ETN98372.1 - 1.8 7.1 4.2 2.4 6.7 2.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DOR PF14839.1 ETN98372.1 - 2.2 7.9 11.3 3.4 7.3 7.8 1.3 1 0 0 1 1 1 0 DOR family NPR3 PF03666.8 ETN98372.1 - 2.5 6.5 9.4 3.1 6.2 6.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Sec62 PF03839.11 ETN98372.1 - 2.5 7.4 14.4 3.7 6.9 10.0 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 PBP_sp32 PF07222.7 ETN98372.1 - 3 6.9 7.3 5.8 6.0 5.1 1.4 2 0 0 2 2 2 0 Proacrosin binding protein sp32 DUF2413 PF10310.4 ETN98372.1 - 3.1 6.4 14.8 4.1 6.1 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) YqfQ PF14181.1 ETN98372.1 - 3.3 7.7 15.0 5.1 7.1 10.4 1.3 1 0 0 1 1 1 0 YqfQ-like protein Ndc1_Nup PF09531.5 ETN98372.1 - 3.9 5.7 5.7 4.2 5.6 3.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Menin PF05053.8 ETN98372.1 - 5.3 5.0 8.3 6 4.9 5.7 1.2 1 0 0 1 1 1 0 Menin NARP1 PF12569.3 ETN98372.1 - 6.1 5.4 14.0 10 4.7 9.7 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Conotoxin PF02950.12 ETN98372.1 - 9.8 7.0 9.9 1.7e+02 3.0 6.9 2.3 1 1 0 1 1 1 0 Conotoxin YL1 PF05764.8 ETN98373.1 - 0.22 11.1 11.1 0.22 11.1 7.7 1.0 1 0 0 1 1 1 0 YL1 nuclear protein DUF912 PF06024.7 ETN98373.1 - 0.43 10.6 3.4 0.49 10.4 2.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Spt5_N PF11942.3 ETN98373.1 - 1.4 9.6 16.1 1.5 9.5 11.2 1.0 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal XAP5 PF04921.9 ETN98373.1 - 2.4 7.6 9.5 2.8 7.4 6.6 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator eIF3_subunit PF08597.5 ETN98373.1 - 2.9 7.4 13.0 3.1 7.2 9.0 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Med19 PF10278.4 ETN98373.1 - 3.1 7.4 7.3 3.3 7.3 5.1 1.0 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Nop14 PF04147.7 ETN98373.1 - 4.3 5.1 14.0 4.1 5.1 9.7 1.0 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.7 ETN98373.1 - 4.3 6.3 15.6 4.7 6.2 10.8 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4637 PF15470.1 ETN98373.1 - 5.4 6.6 11.9 5.7 6.5 8.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) EIF4E-T PF10477.4 ETN98373.1 - 9.5 4.8 9.6 11 4.7 6.7 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF4014 PF13198.1 ETN98374.1 - 0.035 14.4 0.1 0.074 13.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4014) DUF2830 PF11125.3 ETN98375.1 - 0.01 15.5 0.0 0.023 14.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2830) DNA_pol3_delta2 PF13177.1 ETN98375.1 - 0.56 9.8 5.9 6.4 6.4 1.2 2.6 2 1 0 2 2 2 0 DNA polymerase III, delta subunit DUF4014 PF13198.1 ETN98378.1 - 0.034 14.5 1.6 0.043 14.2 0.1 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF4014) RelA_SpoT PF04607.12 ETN98379.1 - 0.00013 21.9 0.2 0.00013 21.9 0.2 2.1 2 0 0 2 2 2 1 Region found in RelA / SpoT proteins NACHT PF05729.7 ETN98379.1 - 0.0003 20.4 0.0 0.00095 18.8 0.0 1.9 1 0 0 1 1 1 1 NACHT domain KaiC PF06745.8 ETN98379.1 - 0.005 15.9 0.0 0.043 12.9 0.0 2.4 3 0 0 3 3 3 1 KaiC AAA_22 PF13401.1 ETN98379.1 - 0.0057 16.7 0.0 0.023 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETN98379.1 - 0.0059 16.9 0.7 0.048 13.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 ETN98379.1 - 0.01 16.6 0.0 0.074 13.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 ETN98379.1 - 0.015 14.9 0.0 0.16 11.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 ETN98379.1 - 0.028 13.3 0.0 0.069 12.0 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF258 PF03193.11 ETN98379.1 - 0.032 13.4 0.2 0.079 12.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_30 PF13604.1 ETN98379.1 - 0.039 13.5 0.0 0.094 12.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 ETN98379.1 - 0.04 14.0 0.0 0.18 11.9 0.0 2.2 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.21 ETN98379.1 - 0.091 12.2 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain WD40 PF00400.27 ETN98380.1 - 7.3e-53 174.6 9.1 8.5e-09 34.9 0.1 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETN98380.1 - 1.6e-07 29.8 11.5 0.0068 14.5 0.1 4.1 2 1 2 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 ETN98380.1 - 4.6e-07 29.7 0.8 0.0085 15.8 0.0 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETN98380.1 - 0.019 13.3 1.0 0.77 7.9 0.3 2.5 1 1 1 2 2 2 0 Cytochrome D1 heme domain MraZ PF02381.13 ETN98380.1 - 0.051 13.3 0.7 3.1 7.6 0.0 3.3 2 1 1 3 3 3 0 MraZ protein DUF2316 PF10078.4 ETN98381.1 - 0.027 14.4 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) DUF809 PF05663.6 ETN98381.1 - 1.5 8.7 4.6 1.6 8.6 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF809) WD40 PF00400.27 ETN98382.1 - 4e-08 32.8 0.2 6.7e-08 32.1 0.2 1.4 1 0 0 1 1 1 1 WD domain, G-beta repeat Nup160 PF11715.3 ETN98382.1 - 0.011 13.9 0.1 0.013 13.6 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Zwint PF15556.1 ETN98382.1 - 0.033 13.4 8.8 0.042 13.0 6.1 1.2 1 0 0 1 1 1 0 ZW10 interactor Sec23_helical PF04815.10 ETN98382.1 - 0.047 13.1 1.2 0.062 12.7 0.8 1.3 1 0 0 1 1 1 0 Sec23/Sec24 helical domain ADIP PF11559.3 ETN98382.1 - 0.081 12.8 16.6 0.12 12.3 11.5 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Cob_adeno_trans PF01923.13 ETN98382.1 - 0.33 10.7 3.1 0.49 10.1 2.1 1.3 1 0 0 1 1 1 0 Cobalamin adenosyltransferase TMEM51 PF15345.1 ETN98382.1 - 0.4 10.3 3.5 0.51 9.9 2.4 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 DUF3573 PF12097.3 ETN98382.1 - 0.41 9.2 3.6 0.43 9.1 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF342 PF03961.8 ETN98382.1 - 1.7 6.9 13.7 1.8 6.8 9.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PhoU PF01895.14 ETN98382.1 - 2.2 8.7 8.5 8.7 6.8 0.3 2.2 1 1 1 2 2 2 0 PhoU domain TALPID3 PF15324.1 ETN98382.1 - 3.2 4.9 8.0 3.8 4.7 5.6 1.0 1 0 0 1 1 1 0 Hedgehog signalling target CCDC74_C PF14917.1 ETN98382.1 - 3.4 7.7 6.7 1.1 9.3 2.0 1.9 1 1 1 2 2 2 0 Coiled coil protein 74, C terminal DUF848 PF05852.6 ETN98382.1 - 4.1 7.2 12.3 5.3 6.8 8.5 1.2 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Prominin PF05478.6 ETN98382.1 - 4.3 4.7 8.8 5.1 4.5 6.1 1.0 1 0 0 1 1 1 0 Prominin DUF3753 PF12575.3 ETN98383.1 - 0.065 13.0 0.4 0.19 11.5 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) TSGP1 PF07771.6 ETN98384.1 - 0.85 9.5 5.0 0.9 9.4 3.4 1.0 1 0 0 1 1 1 0 Tick salivary peptide group 1 RRP14 PF15459.1 ETN98384.1 - 2.2 8.3 5.9 2.4 8.3 4.1 1.1 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 DUF912 PF06024.7 ETN98384.1 - 3.6 7.7 12.0 3.7 7.6 8.3 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2718 PF10918.3 ETN98384.1 - 6.9 6.7 8.5 7.8 6.5 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2718) DUF4167 PF13763.1 ETN98384.1 - 7.3 6.6 11.6 8.2 6.5 8.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4167) DUF4652 PF15525.1 ETN98384.1 - 8 5.8 13.4 8.8 5.7 9.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) TPR_12 PF13424.1 ETN98385.1 - 6.1e-37 125.4 10.6 2.3e-19 69.0 1.2 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETN98385.1 - 1.6e-22 78.0 14.7 1.1e-07 31.0 0.6 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETN98385.1 - 2.6e-22 78.2 17.4 4.5e-13 48.6 3.1 2.6 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 ETN98385.1 - 3.4e-21 73.3 9.1 9.7e-07 28.2 0.0 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETN98385.1 - 4.6e-16 57.3 19.2 4.9e-05 22.8 1.5 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETN98385.1 - 5.9e-16 57.8 0.0 0.00046 20.0 0.0 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETN98385.1 - 7.7e-14 50.3 0.4 0.0015 18.1 0.0 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETN98385.1 - 1.9e-10 41.1 0.1 1.8e-05 25.2 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETN98385.1 - 3.6e-08 33.3 0.3 0.095 13.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETN98385.1 - 6.2e-08 32.2 8.5 0.018 15.1 0.2 3.7 3 2 0 3 3 3 3 Tetratricopeptide repeat Apc3 PF12895.2 ETN98385.1 - 4.4e-06 26.7 10.4 0.00076 19.5 2.3 2.7 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF627 PF04781.7 ETN98385.1 - 2.4e-05 23.9 5.3 0.61 9.7 0.1 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF627) SNAP PF14938.1 ETN98385.1 - 4.2e-05 22.8 4.4 0.00013 21.1 3.1 1.4 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_14 PF13428.1 ETN98385.1 - 0.0003 21.1 0.0 4.8 8.0 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Prefoldin PF02996.12 ETN98385.1 - 0.0023 17.5 1.7 0.37 10.4 0.0 2.9 2 1 0 3 3 3 1 Prefoldin subunit TPR_3 PF07720.7 ETN98385.1 - 0.0054 16.5 9.4 0.027 14.2 0.6 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETN98385.1 - 0.0079 15.4 0.0 4.6 6.5 0.0 2.8 3 0 0 3 3 3 1 SHNi-TPR TPR_19 PF14559.1 ETN98385.1 - 0.012 15.9 0.0 0.49 10.7 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat MbeB_N PF04837.7 ETN98385.1 - 0.078 13.0 0.7 16 5.6 0.0 2.8 3 0 0 3 3 3 0 MbeB-like, N-term conserved region DUF2225 PF09986.4 ETN98385.1 - 0.11 11.8 6.7 2.1 7.7 4.7 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) RPN7 PF10602.4 ETN98385.1 - 0.27 10.5 5.9 2.8 7.2 0.2 2.1 1 1 0 2 2 2 0 26S proteasome subunit RPN7 Neuro_bHLH PF12533.3 ETN98385.1 - 0.45 11.3 3.4 0.83 10.4 0.8 2.0 1 1 1 2 2 2 0 Neuronal helix-loop-helix transcription factor DUF1832 PF08870.6 ETN98385.1 - 0.65 9.7 2.8 2.4 7.8 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1832) MIT PF04212.13 ETN98385.1 - 1.1 9.1 7.7 11 5.9 0.1 3.0 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain Tho2 PF11262.3 ETN98385.1 - 2.9 6.8 11.1 3 6.8 0.7 2.5 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF386 PF04074.7 ETN98385.1 - 3.7 7.0 8.3 13 5.2 5.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF386) PUB PF09409.5 ETN98386.1 - 0.018 14.7 1.4 0.058 13.1 0.9 2.0 1 1 0 1 1 1 0 PUB domain SPARC_Ca_bdg PF10591.4 ETN98389.1 - 0.059 13.4 0.5 0.059 13.4 0.4 1.7 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region zf-HC5HC2H_2 PF13832.1 ETN98389.1 - 0.061 13.3 0.4 0.11 12.4 0.3 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 ETN98389.1 - 0.099 12.8 1.2 0.23 11.6 0.8 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain Lipoprotein_8 PF02030.10 ETN98390.1 - 0.14 10.6 3.2 0.14 10.6 2.2 1.1 1 0 0 1 1 1 0 Hypothetical lipoprotein (MG045 family) Cas_Csy4 PF09618.5 ETN98390.1 - 0.17 11.7 3.2 0.23 11.2 2.2 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) AAA_23 PF13476.1 ETN98390.1 - 0.5 10.6 14.3 0.64 10.3 9.9 1.2 1 0 0 1 1 1 0 AAA domain PBP_sp32 PF07222.7 ETN98390.1 - 0.69 9.0 24.5 0.25 10.4 15.8 1.4 1 1 0 1 1 1 0 Proacrosin binding protein sp32 AAR2 PF05282.6 ETN98390.1 - 1.3 7.8 8.3 1.5 7.7 5.8 1.1 1 0 0 1 1 1 0 AAR2 protein CENP-N PF05238.8 ETN98390.1 - 2.3 7.1 10.0 2.6 6.9 6.9 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like CBF_beta PF02312.12 ETN98390.1 - 8.8 5.9 14.5 14 5.2 8.6 1.9 1 1 1 2 2 2 0 Core binding factor beta subunit DUF1510 PF07423.6 ETN98390.1 - 9.5 5.5 24.8 0.96 8.7 10.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF1669 PF07894.7 ETN98390.1 - 10 5.2 9.8 1.8 7.7 4.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1669) Pex14_N PF04695.8 ETN98391.1 - 0.0022 18.0 0.8 0.003 17.5 0.5 1.2 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region EVI2A PF05399.6 ETN98391.1 - 0.007 15.6 2.5 0.0093 15.2 1.8 1.2 1 0 0 1 1 1 1 Ectropic viral integration site 2A protein (EVI2A) DUF1517 PF07466.6 ETN98391.1 - 0.024 13.6 4.1 0.043 12.8 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) BUD22 PF09073.5 ETN98391.1 - 0.11 11.6 8.4 0.15 11.1 5.8 1.2 1 0 0 1 1 1 0 BUD22 Herpes_UL33 PF03581.8 ETN98391.1 - 0.14 12.0 1.2 0.26 11.2 0.4 1.7 2 0 0 2 2 2 0 Herpesvirus UL33-like protein Pol_alpha_B_N PF08418.5 ETN98391.1 - 0.23 10.9 9.9 0.3 10.5 6.9 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Herpes_capsid PF06112.6 ETN98391.1 - 0.26 11.3 17.1 0.38 10.7 11.9 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Gag_spuma PF03276.9 ETN98391.1 - 0.33 9.2 3.3 0.41 8.9 2.3 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DUF4614 PF15391.1 ETN98391.1 - 0.76 9.5 15.3 1.2 8.8 10.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Apt1 PF10351.4 ETN98391.1 - 0.94 8.2 11.3 1.2 7.9 7.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain POX PF07526.6 ETN98391.1 - 1.4 9.1 5.2 6.4 7.0 2.0 2.2 2 0 0 2 2 2 0 Associated with HOX RAP1 PF07218.6 ETN98391.1 - 1.9 6.4 15.3 2.2 6.2 10.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.4 ETN98391.1 - 2 6.5 14.7 2.5 6.2 10.2 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF566 PF04484.7 ETN98391.1 - 2.5 7.5 15.5 3.1 7.2 10.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF515 PF04415.7 ETN98391.1 - 2.8 6.1 15.2 3.7 5.6 10.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Corona_nucleoca PF00937.13 ETN98391.1 - 6.3 5.6 14.7 8.7 5.1 10.2 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Secretin_N_2 PF07655.8 ETN98391.1 - 8.7 6.8 22.4 17 5.8 15.5 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Pex14_N PF04695.8 ETN98392.1 - 0.62 10.1 8.1 0.79 9.7 5.6 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HCO3_cotransp PF00955.16 ETN98392.1 - 1.4 7.5 3.9 1.4 7.5 2.7 1.0 1 0 0 1 1 1 0 HCO3- transporter family GHBP PF12772.2 ETN98392.1 - 1.5 8.1 11.4 1.8 7.8 7.6 1.4 1 1 0 1 1 1 0 Growth hormone receptor binding Zip PF02535.17 ETN98392.1 - 1.9 7.4 4.9 2 7.3 3.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.12 ETN98392.1 - 2.4 6.9 7.6 2.5 6.8 5.3 1.0 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.11 ETN98392.1 - 3.4 7.4 6.3 3.8 7.3 4.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Macoilin PF09726.4 ETN98392.1 - 3.5 5.7 10.9 3.8 5.6 7.5 1.0 1 0 0 1 1 1 0 Transmembrane protein FAM60A PF15396.1 ETN98392.1 - 5.8 6.5 7.2 6.7 6.3 5.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A RP-C_C PF11800.3 ETN98392.1 - 7.4 6.2 9.2 9.2 5.9 6.4 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF1754 PF08555.5 ETN98393.1 - 6.8 7.3 16.7 10 6.7 11.6 1.2 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) DUF2098 PF09871.4 ETN98394.1 - 0.062 13.2 2.3 0.51 10.2 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) FHA PF00498.21 ETN98395.1 - 1.6e-06 28.1 0.5 3.6e-06 26.9 0.1 1.8 2 0 0 2 2 2 1 FHA domain CDC73 PF05179.9 ETN98395.1 - 0.032 13.6 1.1 0.045 13.1 0.7 1.1 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family Prp31_C PF09785.4 ETN98395.1 - 0.067 13.6 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 Prp31 C terminal domain WD40 PF00400.27 ETN98396.1 - 1.2e-12 47.2 0.3 2.7e-06 27.0 0.2 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETN98396.1 - 0.035 12.8 0.1 0.035 12.8 0.1 1.1 1 0 0 1 1 1 0 Nup133 N terminal like RGS PF00615.14 ETN98397.1 - 0.032 14.3 0.3 0.079 13.0 0.2 1.6 1 0 0 1 1 1 0 Regulator of G protein signaling domain EST1 PF10374.4 ETN98397.1 - 0.21 11.6 2.8 0.45 10.5 1.9 1.9 1 1 0 1 1 1 0 Telomerase activating protein Est1 CAP18_C PF12153.3 ETN98397.1 - 6.4 6.5 8.5 27 4.5 0.0 3.5 4 0 0 4 4 4 0 LPS binding domain of CAP18 (C terminal) PABP PF00658.13 ETN98398.1 - 0.003 17.1 0.9 0.0051 16.4 0.0 1.9 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain WD40 PF00400.27 ETN98399.1 - 7.6e-65 212.6 27.7 1.2e-11 44.0 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETN98399.1 - 5.1e-12 44.7 5.6 0.011 13.8 0.1 5.1 1 1 4 5 5 5 5 Nucleoporin Nup120/160 TraC PF07820.7 ETN98400.1 - 0.034 14.3 0.1 0.075 13.2 0.0 1.6 2 0 0 2 2 2 0 TraC-like protein TPR_12 PF13424.1 ETN98404.1 - 3.2e-27 94.2 2.9 7.4e-14 51.4 0.3 2.1 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETN98404.1 - 6.8e-18 63.4 12.1 3.4e-09 35.9 0.3 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETN98404.1 - 1.3e-16 59.8 1.7 1.9e-06 27.6 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETN98404.1 - 5.9e-16 56.9 2.9 5.4e-07 28.9 0.1 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETN98404.1 - 1.7e-15 56.3 2.9 3.9e-07 29.6 0.7 2.1 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 ETN98404.1 - 3e-13 48.5 8.0 2.3e-06 27.0 0.5 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETN98404.1 - 6.2e-10 38.1 10.7 5.4e-07 28.9 0.5 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETN98404.1 - 4.9e-08 32.5 4.3 0.0037 17.3 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETN98404.1 - 2.3e-05 24.1 4.6 0.016 15.1 0.2 2.2 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 ETN98404.1 - 3e-05 23.7 1.3 0.15 11.9 0.1 2.1 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain TPR_14 PF13428.1 ETN98404.1 - 0.00013 22.2 0.0 0.55 11.0 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat PPR PF01535.15 ETN98404.1 - 0.0003 20.5 0.4 0.083 12.9 0.0 2.7 2 1 1 3 3 3 1 PPR repeat TPR_16 PF13432.1 ETN98404.1 - 0.0013 19.3 0.1 1.4 9.7 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETN98404.1 - 0.0019 18.5 0.1 0.3 11.6 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF627 PF04781.7 ETN98404.1 - 0.039 13.5 0.5 2.6 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF627) Apc3 PF12895.2 ETN98404.1 - 0.048 13.8 3.8 0.29 11.3 1.8 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Cohesin_load PF10345.4 ETN98404.1 - 0.052 11.7 1.5 0.59 8.2 0.3 2.0 1 1 1 2 2 2 0 Cohesin loading factor TPR_19 PF14559.1 ETN98404.1 - 0.072 13.4 0.2 0.46 10.8 0.1 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat Sel1 PF08238.7 ETN98404.1 - 0.075 13.7 2.7 7.6 7.3 0.1 2.6 2 0 0 2 2 2 0 Sel1 repeat Lantibiotic_a PF14867.1 ETN98404.1 - 0.23 10.7 1.9 18 4.6 0.0 3.0 3 0 0 3 3 3 0 Lantibiotic alpha Peptidase_M3_N PF08439.5 ETN98406.1 - 0.057 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Oligopeptidase F EFG_IV PF03764.13 ETN98409.1 - 3.2e-21 75.1 0.0 4.5e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 ETN98409.1 - 2.1e-20 72.3 0.0 3.4e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor G C-terminus Kelch_4 PF13418.1 ETN98410.1 - 1.8e-06 27.6 0.2 0.021 14.5 0.0 2.5 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETN98410.1 - 8.4e-06 25.7 4.9 0.0021 18.1 0.1 2.7 2 1 1 3 3 3 2 Kelch motif Kelch_1 PF01344.20 ETN98410.1 - 2e-05 24.0 3.3 0.057 12.9 0.0 3.0 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 ETN98410.1 - 0.00041 20.2 4.7 0.027 14.4 0.1 3.0 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 ETN98410.1 - 0.00048 19.7 0.3 0.94 9.3 0.1 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 ETN98410.1 - 0.15 12.3 0.1 13 6.1 0.0 2.3 2 0 0 2 2 2 0 Galactose oxidase, central domain Fib_alpha PF08702.5 ETN98411.1 - 0.079 13.0 1.1 0.092 12.8 0.8 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Uteroglobin PF01099.12 ETN98411.1 - 0.13 12.0 0.8 0.58 9.9 0.4 2.1 1 1 1 2 2 2 0 Uteroglobin family EphA2_TM PF14575.1 ETN98412.1 - 0.021 15.1 1.0 0.021 15.1 0.7 2.7 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.6 ETN98412.1 - 0.034 13.7 0.7 0.034 13.7 0.5 2.2 2 1 0 2 2 2 0 Protocadherin DUF929 PF06053.6 ETN98412.1 - 0.037 13.1 1.4 0.061 12.3 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF929) DUF4381 PF14316.1 ETN98412.1 - 0.039 14.0 0.4 0.066 13.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Myc_target_1 PF15179.1 ETN98412.1 - 0.36 10.3 8.3 0.25 10.9 0.7 2.2 2 0 0 2 2 2 0 Myc target protein 1 PspB PF06667.7 ETN98412.1 - 0.47 10.4 5.6 0.81 9.6 3.8 1.5 1 1 0 1 1 1 0 Phage shock protein B 60KD_IMP PF02096.15 ETN98412.1 - 0.75 9.4 10.7 1.4 8.5 7.4 1.4 1 0 0 1 1 1 0 60Kd inner membrane protein SCFA_trans PF02667.9 ETN98412.1 - 0.76 8.4 5.1 1 8.0 3.5 1.1 1 0 0 1 1 1 0 Short chain fatty acid transporter 7TM_GPCR_Srd PF10317.4 ETN98412.1 - 0.87 8.5 7.7 1.5 7.7 5.3 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd WBP-1 PF11669.3 ETN98412.1 - 1.2 9.2 4.8 1.2 9.2 1.5 2.2 2 2 0 2 2 2 0 WW domain-binding protein 1 FAM91_C PF14648.1 ETN98412.1 - 1.2 7.8 6.0 0.29 9.9 1.7 1.6 2 0 0 2 2 2 0 FAM91 C-terminus BNIP3 PF06553.7 ETN98412.1 - 1.2 8.4 6.5 0.68 9.2 2.6 1.8 2 0 0 2 2 2 0 BNIP3 MLANA PF14991.1 ETN98412.1 - 2 8.4 4.9 0.55 10.2 0.3 2.1 2 1 0 2 2 2 0 Protein melan-A Desulfoferrodox PF01880.13 ETN98412.1 - 2 8.7 7.0 0.8 10.0 0.9 2.2 2 0 0 2 2 2 0 Desulfoferrodoxin DUF1510 PF07423.6 ETN98412.1 - 2.1 7.6 19.2 0.38 10.1 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) TMEM154 PF15102.1 ETN98412.1 - 4.1 7.1 21.2 0.08 12.6 4.2 2.4 2 0 0 2 2 2 0 TMEM154 protein family Baculo_11_kDa PF06143.6 ETN98412.1 - 4.1 6.8 9.0 0.33 10.3 2.5 2.1 2 0 0 2 2 2 0 Baculovirus 11 kDa family TMEM51 PF15345.1 ETN98412.1 - 4.8 6.8 8.8 0.88 9.2 0.6 2.2 2 0 0 2 2 2 0 Transmembrane protein 51 Pex24p PF06398.6 ETN98412.1 - 5.1 5.7 10.3 0.14 10.9 0.8 2.0 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Chordopox_G3 PF06129.7 ETN98412.1 - 5.5 7.1 7.3 0.39 10.8 1.0 2.0 2 0 0 2 2 2 0 Chordopoxvirus G3 protein PIG-P PF08510.7 ETN98412.1 - 6.2 6.4 7.5 16 5.1 5.2 1.9 1 1 0 1 1 1 0 PIG-P Peptidase_M56 PF05569.6 ETN98412.1 - 8.5 5.2 8.9 0.43 9.5 2.2 1.6 2 0 0 2 2 2 0 BlaR1 peptidase M56 Gp37 PF09646.5 ETN98413.1 - 0.045 13.2 0.2 0.34 10.3 0.0 2.1 2 0 0 2 2 2 0 Gp37 protein DUF3699 PF12480.3 ETN98413.1 - 0.083 12.5 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3699) YqfQ PF14181.1 ETN98414.1 - 1.1 9.2 6.1 1.3 9.0 4.2 1.1 1 0 0 1 1 1 0 YqfQ-like protein ERF PF04404.7 ETN98414.1 - 2 7.9 8.4 3.4 7.1 4.9 1.8 1 1 1 2 2 2 0 ERF superfamily Rpn3_C PF08375.6 ETN98415.1 - 0.049 14.0 1.7 0.049 14.0 1.2 2.2 1 1 1 2 2 2 0 Proteasome regulatory subunit C-terminal Dala_Dala_lig_N PF01820.16 ETN98416.1 - 0.013 15.8 0.0 0.025 14.9 0.0 1.5 1 1 0 1 1 1 0 D-ala D-ala ligase N-terminus TPR_2 PF07719.12 ETN98418.1 - 1.1e-05 24.9 0.4 0.28 11.1 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETN98418.1 - 2.3e-05 23.9 3.9 0.029 14.0 0.2 2.3 2 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETN98418.1 - 0.00013 21.4 0.4 0.28 10.8 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETN98418.1 - 0.0064 17.0 1.4 0.54 11.0 0.1 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETN98418.1 - 0.015 15.6 1.5 0.06 13.6 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETN98418.1 - 0.048 14.3 2.7 0.89 10.3 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETN98418.1 - 0.06 13.2 6.6 0.88 9.5 0.7 2.6 1 1 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETN98418.1 - 0.068 13.0 0.8 0.15 11.9 0.6 1.5 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.1 ETN98418.1 - 0.12 11.4 1.2 0.26 10.3 0.1 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat PyrI PF01948.13 ETN98419.1 - 0.037 14.0 0.3 0.045 13.7 0.2 1.2 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, allosteric domain OGG_N PF07934.7 ETN98419.1 - 0.12 12.3 0.2 0.17 11.8 0.1 1.3 1 1 0 1 1 1 0 8-oxoguanine DNA glycosylase, N-terminal domain CagY_M PF07337.6 ETN98419.1 - 2.9 7.4 6.7 1.4 8.4 1.5 2.3 2 0 0 2 2 2 0 DC-EC Repeat Cation_ATPase_C PF00689.16 ETN98421.1 - 1.9e-11 43.8 0.1 3.6e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 ETN98421.1 - 0.15 12.4 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Toxin_10 PF05431.6 ETN98422.1 - 0.023 14.3 2.4 0.038 13.6 1.0 1.7 2 0 0 2 2 2 0 Insecticidal Crystal Toxin, P42 CENP-B_N PF04218.8 ETN98423.1 - 0.11 11.8 0.1 0.45 9.9 0.0 2.0 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Peptidase_C14 PF00656.17 ETN98424.1 - 0.0098 15.6 0.0 0.0099 15.5 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Methyltransf_7 PF03492.10 ETN98425.1 - 0.036 12.8 0.0 0.053 12.2 0.0 1.2 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase Ribonuc_2-5A PF06479.7 ETN98425.1 - 0.046 13.5 0.3 0.089 12.6 0.1 1.6 1 1 0 1 1 1 0 Ribonuclease 2-5A Sod_Ni PF09055.6 ETN98425.1 - 0.16 12.3 2.0 0.43 10.9 0.4 2.4 1 1 1 2 2 2 0 Nickel-containing superoxide dismutase Lipocalin PF00061.18 ETN98426.1 - 0.11 12.4 0.7 0.17 11.8 0.5 1.3 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family DUF724 PF05266.9 ETN98427.1 - 0.048 13.2 2.3 0.074 12.6 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF3899 PF13038.1 ETN98427.1 - 0.67 10.1 5.0 0.14 12.3 0.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Med19 PF10278.4 ETN98427.1 - 4.1 7.0 11.0 6 6.5 7.6 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 WD40 PF00400.27 ETN98428.1 - 1.2e-12 47.1 3.1 7.3e-09 35.1 0.2 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETN98428.1 - 8.2e-06 24.2 0.5 1.2e-05 23.6 0.3 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 HrpB7 PF09486.5 ETN98428.1 - 0.0034 17.3 9.4 0.011 15.6 6.5 1.8 1 1 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) Filament PF00038.16 ETN98428.1 - 0.0067 15.9 19.3 0.0067 15.9 13.4 2.1 1 1 1 2 2 2 1 Intermediate filament protein Spc7 PF08317.6 ETN98428.1 - 0.049 12.2 46.9 0.034 12.8 19.0 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein TPR_8 PF13181.1 ETN98428.1 - 0.059 13.1 13.8 0.38 10.6 0.8 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Nsp1_C PF05064.8 ETN98428.1 - 0.15 11.7 42.7 0.025 14.1 16.7 2.7 2 1 1 3 3 3 0 Nsp1-like C-terminal region Reo_sigmaC PF04582.7 ETN98428.1 - 0.21 10.7 10.6 0.15 11.1 2.4 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 ETN98428.1 - 0.41 10.7 43.8 0.058 13.5 17.5 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ATG16 PF08614.6 ETN98428.1 - 0.49 10.1 44.2 2.1 8.1 17.0 2.8 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.1 ETN98428.1 - 0.52 8.7 48.4 0.18 10.2 19.9 2.1 1 1 1 2 2 2 0 AAA domain DUF641 PF04859.7 ETN98428.1 - 0.64 9.7 32.3 2.2 8.0 3.1 3.3 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) CENP-F_N PF10481.4 ETN98428.1 - 0.69 9.2 34.2 1.1 8.6 12.9 2.0 1 1 1 2 2 2 0 Cenp-F N-terminal domain DUF2968 PF11180.3 ETN98428.1 - 0.91 8.8 30.8 0.15 11.4 12.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) CALCOCO1 PF07888.6 ETN98428.1 - 1.1 7.5 28.8 1.4 7.0 20.0 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DASH_Hsk3 PF08227.6 ETN98428.1 - 1.4 9.1 11.0 0.53 10.5 2.7 2.6 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like GvpK PF05121.7 ETN98428.1 - 1.7 8.5 24.2 0.14 11.9 2.3 3.3 2 1 0 3 3 3 0 Gas vesicle protein K DUF4200 PF13863.1 ETN98428.1 - 1.7 8.6 53.4 0.033 14.1 15.1 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) Muted PF14942.1 ETN98428.1 - 2.4 8.0 32.4 1.3 8.9 11.9 2.2 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Prefoldin_2 PF01920.15 ETN98428.1 - 2.9 7.6 52.4 0.16 11.7 6.3 4.2 2 1 2 4 4 4 0 Prefoldin subunit Mnd1 PF03962.10 ETN98428.1 - 3.6 7.2 38.8 10 5.7 11.2 2.5 1 1 1 2 2 2 0 Mnd1 family DUF1202 PF06717.6 ETN98428.1 - 3.6 6.7 31.4 3.2 6.9 3.8 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1202) IncA PF04156.9 ETN98428.1 - 3.9 7.0 43.8 2.2 7.8 19.0 2.2 1 1 1 2 2 2 0 IncA protein CENP-F_leu_zip PF10473.4 ETN98428.1 - 4 7.3 44.0 5.8 6.7 14.9 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AhpC-TSA PF00578.16 ETN98428.1 - 4.3 7.0 7.5 2.7 7.7 3.5 2.1 1 1 0 1 1 1 0 AhpC/TSA family DUF4618 PF15397.1 ETN98428.1 - 4.4 6.5 43.4 2.9 7.1 20.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Sec8_exocyst PF04048.9 ETN98428.1 - 5.9 6.5 30.5 0.32 10.6 15.0 2.3 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain TMCO5 PF14992.1 ETN98428.1 - 8 5.5 41.3 9.9 5.1 28.7 1.1 1 0 0 1 1 1 0 TMCO5 family YlqD PF11068.3 ETN98428.1 - 9.8 6.2 46.2 1.1e+02 2.7 8.8 3.3 1 1 1 2 2 2 0 YlqD protein Ribosomal_L21e PF01157.13 ETN98429.1 - 0.1 12.3 0.1 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L21e RICTOR_M PF14666.1 ETN98430.1 - 0.02 13.9 0.1 0.026 13.5 0.1 1.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain BssC_TutF PF08201.6 ETN98430.1 - 0.03 13.8 0.1 0.079 12.4 0.0 1.8 1 0 0 1 1 1 0 BssC/TutF protein Myc_target_1 PF15179.1 ETN98430.1 - 0.075 12.6 0.7 3.2 7.3 0.1 2.2 2 0 0 2 2 2 0 Myc target protein 1 WD40 PF00400.27 ETN98431.1 - 1.4e-49 164.2 13.2 1e-10 41.0 0.0 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETN98431.1 - 5.5e-10 39.2 0.0 2.4e-06 27.4 0.0 3.0 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETN98431.1 - 9.9e-06 25.0 1.7 1.2 8.9 0.1 4.2 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.9 ETN98431.1 - 1e-05 24.5 0.1 0.0011 17.8 0.0 1.6 1 1 1 2 2 2 2 Coatomer WD associated region Cytochrom_D1 PF02239.11 ETN98431.1 - 0.0002 19.8 0.3 0.014 13.7 0.1 2.7 1 1 1 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.3 ETN98431.1 - 0.00031 19.0 1.5 1.3 7.0 0.0 3.6 2 2 1 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETN98431.1 - 0.00095 18.0 5.2 1.3 7.6 0.0 3.9 1 1 4 5 5 5 2 Nup133 N terminal like TFIIIC_delta PF12657.2 ETN98431.1 - 0.0023 17.6 0.4 0.06 13.0 0.0 2.4 2 1 1 3 3 3 1 Transcription factor IIIC subunit delta N-term Proteasome_A_N PF10584.4 ETN98431.1 - 0.011 15.0 2.3 13 5.1 0.0 3.6 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Me-amine-dh_H PF06433.6 ETN98431.1 - 0.021 13.5 0.0 0.057 12.0 0.0 1.7 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) DUF1258 PF06869.7 ETN98431.1 - 0.021 13.9 0.4 0.73 8.8 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1258) PQQ_2 PF13360.1 ETN98431.1 - 0.034 13.5 0.0 0.22 10.9 0.0 2.0 1 1 1 2 2 2 0 PQQ-like domain DUF658 PF04936.7 ETN98432.1 - 0.023 14.5 0.1 0.028 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF658) Man-6-P_recep PF02157.10 ETN98432.1 - 0.046 12.7 0.0 0.047 12.6 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate receptor DUF1387 PF07139.6 ETN98435.1 - 0.0075 15.9 5.1 0.0094 15.5 3.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1387) DUF2721 PF11026.3 ETN98435.1 - 0.056 13.0 3.9 0.034 13.7 1.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) Apis_Csd PF11671.3 ETN98435.1 - 0.98 9.2 7.2 1.4 8.6 5.0 1.2 1 0 0 1 1 1 0 Complementary sex determiner protein Pex14_N PF04695.8 ETN98435.1 - 1.2 9.1 5.2 0.18 11.8 0.2 2.0 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Secretin_N_2 PF07655.8 ETN98435.1 - 1.5 9.2 10.9 0.17 12.2 4.2 1.9 2 0 0 2 2 2 0 Secretin N-terminal domain AAA PF00004.24 ETN98436.1 - 7.6e-09 35.8 0.0 0.00048 20.3 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETN98436.1 - 1.8e-07 30.9 0.1 9.4e-05 22.1 0.0 3.6 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETN98436.1 - 2.1e-06 27.9 0.1 0.094 12.8 0.0 3.6 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 ETN98436.1 - 8.1e-05 22.6 0.1 0.018 15.0 0.0 3.2 2 1 1 3 3 3 1 AAA ATPase domain ABC_tran PF00005.22 ETN98436.1 - 0.0003 21.0 0.0 0.0012 19.1 0.0 2.0 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 ETN98436.1 - 0.00069 18.8 0.0 0.0021 17.2 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Sigma54_activ_2 PF14532.1 ETN98436.1 - 0.0017 18.4 0.0 0.055 13.5 0.0 2.9 3 0 0 3 3 3 1 Sigma-54 interaction domain PduV-EutP PF10662.4 ETN98436.1 - 0.0089 15.5 0.1 0.032 13.7 0.0 2.0 2 0 0 2 2 1 1 Ethanolamine utilisation - propanediol utilisation UPF0079 PF02367.12 ETN98436.1 - 0.0096 15.5 0.0 0.035 13.7 0.0 2.0 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_14 PF13173.1 ETN98436.1 - 0.014 15.2 0.0 0.11 12.3 0.0 2.7 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 ETN98436.1 - 0.021 15.3 0.0 0.074 13.5 0.0 2.0 1 0 0 1 1 1 0 Miro-like protein AAA_24 PF13479.1 ETN98436.1 - 0.034 13.7 0.2 0.5 9.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 ETN98436.1 - 0.035 13.5 0.0 0.31 10.4 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.8 ETN98436.1 - 0.036 13.0 0.0 0.094 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.7 ETN98436.1 - 0.043 13.4 1.3 0.65 9.6 0.1 3.1 3 0 0 3 3 3 0 NACHT domain MCM PF00493.18 ETN98436.1 - 0.056 12.2 0.1 0.24 10.1 0.0 2.1 2 0 0 2 2 2 0 MCM2/3/5 family DUF1743 PF08489.6 ETN98436.1 - 0.074 12.8 0.0 0.48 10.1 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1743) Mg_chelatase PF01078.16 ETN98436.1 - 0.14 11.2 0.1 7.7 5.6 0.0 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 ETN98436.1 - 0.41 10.4 0.7 7.4 6.4 0.1 2.4 2 0 0 2 2 2 0 Part of AAA domain TMF_DNA_bd PF12329.3 ETN98439.1 - 1.1e-06 28.3 63.1 0.012 15.4 9.5 4.0 1 1 3 4 4 4 4 TATA element modulatory factor 1 DNA binding CCDC155 PF14662.1 ETN98439.1 - 0.0026 17.3 46.6 0.055 13.0 8.0 3.1 1 1 2 3 3 3 3 Coiled-coil region of CCDC155 Reo_sigmaC PF04582.7 ETN98439.1 - 0.005 16.0 7.3 0.0075 15.4 2.4 1.9 1 1 1 2 2 2 2 Reovirus sigma C capsid protein CHASE3 PF05227.8 ETN98439.1 - 0.011 15.4 24.5 0.52 9.9 3.5 4.1 1 1 2 3 3 3 0 CHASE3 domain Spectrin PF00435.16 ETN98439.1 - 0.015 15.6 36.7 0.41 10.9 7.4 3.1 1 1 2 3 3 3 0 Spectrin repeat bZIP_Maf PF03131.12 ETN98439.1 - 0.05 13.8 38.4 1.6 9.0 1.9 4.5 1 1 4 5 5 5 0 bZIP Maf transcription factor DivIC PF04977.10 ETN98439.1 - 0.082 12.3 59.1 0.44 10.0 6.5 5.2 1 1 4 5 5 5 0 Septum formation initiator APG6 PF04111.7 ETN98439.1 - 0.21 10.5 50.0 0.086 11.8 20.7 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 Med9 PF07544.8 ETN98439.1 - 0.21 11.3 43.1 0.077 12.7 4.4 5.1 1 1 4 6 6 6 0 RNA polymerase II transcription mediator complex subunit 9 GAS PF13851.1 ETN98439.1 - 0.41 9.8 56.8 0.18 10.9 23.2 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4446 PF14584.1 ETN98439.1 - 0.44 10.3 34.8 1.3 8.7 1.4 4.6 1 1 4 5 5 5 0 Protein of unknown function (DUF4446) Mod_r PF07200.8 ETN98439.1 - 0.75 9.7 45.8 0.38 10.6 12.0 3.0 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF2570 PF10828.3 ETN98439.1 - 0.81 9.3 40.3 2.2 7.9 4.6 4.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2570) LTXXQ PF07813.7 ETN98439.1 - 0.82 10.1 30.5 6 7.3 1.8 4.5 1 1 2 3 3 3 0 LTXXQ motif family protein DUF16 PF01519.11 ETN98439.1 - 0.86 9.8 48.5 5.1e+02 0.9 18.4 4.0 1 1 1 2 2 1 0 Protein of unknown function DUF16 IncA PF04156.9 ETN98439.1 - 1.2 8.7 45.3 0.27 10.8 16.5 2.4 1 1 1 2 2 2 0 IncA protein HAUS-augmin3 PF14932.1 ETN98439.1 - 1.3 8.1 42.9 0.95 8.5 11.1 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 CorA PF01544.13 ETN98439.1 - 1.5 7.7 20.2 0.094 11.7 6.8 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF1843 PF08898.5 ETN98439.1 - 1.6 8.7 23.1 1.4 9.0 0.3 5.2 1 1 5 6 6 6 0 Domain of unknown function (DUF1843) ADIP PF11559.3 ETN98439.1 - 1.8 8.4 49.1 13 5.6 9.6 2.9 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF2968 PF11180.3 ETN98439.1 - 2.7 7.3 36.3 0.13 11.6 7.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) DUF2935 PF11155.3 ETN98439.1 - 3.8 7.6 25.8 16 5.5 7.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Striatin PF08232.7 ETN98439.1 - 4.6 7.5 39.1 5.4 7.3 14.0 2.5 1 1 1 2 2 2 0 Striatin family Phage_GP20 PF06810.6 ETN98439.1 - 6 6.2 63.1 1.3 8.5 5.3 4.2 1 1 3 4 4 4 0 Phage minor structural protein GP20 Fib_alpha PF08702.5 ETN98439.1 - 7.1 6.7 40.7 40 4.2 16.1 2.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF972 PF06156.8 ETN98439.1 - 7.3 6.9 43.7 10 6.5 8.2 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF972) FAM60A PF15396.1 ETN98440.1 - 0.6 9.8 16.3 0.83 9.3 11.3 1.3 1 0 0 1 1 1 0 Protein Family FAM60A SprA-related PF12118.3 ETN98440.1 - 2.8 7.2 23.4 3.5 6.8 16.2 1.0 1 0 0 1 1 1 0 SprA-related family Macoilin PF09726.4 ETN98440.1 - 9 4.4 21.6 11 4.1 15.0 1.0 1 0 0 1 1 1 0 Transmembrane protein DNA_topoisoIV PF00521.15 ETN98441.1 - 0.00024 20.0 8.2 0.00024 20.0 5.7 1.9 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DUF2232 PF09991.4 ETN98441.1 - 0.028 13.4 0.2 0.043 12.7 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) TCP PF03634.8 ETN98441.1 - 6.5 7.1 16.2 0.31 11.3 3.3 2.1 2 0 0 2 2 2 0 TCP family transcription factor DNA_gyraseB PF00204.20 ETN98443.1 - 1.3e-20 73.2 8.7 1.3e-20 73.2 6.0 2.2 2 0 0 2 2 2 1 DNA gyrase B Toprim PF01751.17 ETN98443.1 - 1.1e-14 54.1 0.0 1.1e-14 54.1 0.0 2.8 2 1 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 ETN98443.1 - 9.2e-11 41.4 0.0 1.9e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WASH-7_N PF14745.1 ETN98444.1 - 0.033 12.3 1.0 0.039 12.1 0.7 1.1 1 0 0 1 1 1 0 WASH complex subunit 7, N-terminal gp45-slide_C PF09116.5 ETN98445.1 - 0.046 13.7 0.3 0.065 13.2 0.2 1.3 1 0 0 1 1 1 0 gp45 sliding clamp, C terminal Kelch_1 PF01344.20 ETN98446.1 - 4.1e-08 32.6 1.5 0.0003 20.2 0.1 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 ETN98446.1 - 3.9e-07 29.7 0.1 0.011 15.4 0.0 2.3 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETN98446.1 - 3.1e-06 27.1 1.3 0.02 15.0 0.3 2.4 1 1 1 2 2 2 2 Kelch motif Kelch_2 PF07646.10 ETN98446.1 - 1.2e-05 24.8 0.1 0.0016 18.1 0.0 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.1 ETN98446.1 - 0.00028 20.7 1.0 0.19 11.7 0.0 2.3 2 0 0 2 2 2 2 Kelch motif CDC45 PF02724.9 ETN98446.1 - 0.0081 14.2 2.7 0.0081 14.2 1.9 1.1 1 0 0 1 1 1 1 CDC45-like protein Apc9 PF12856.2 ETN98446.1 - 0.014 15.4 2.2 0.023 14.7 1.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 9 Kelch_3 PF13415.1 ETN98446.1 - 0.033 14.3 0.1 15 5.8 0.0 2.7 3 0 0 3 3 3 0 Galactose oxidase, central domain Nucleoplasmin PF03066.10 ETN98446.1 - 0.24 10.9 14.0 0.36 10.3 9.7 1.3 1 0 0 1 1 1 0 Nucleoplasmin Tim54 PF11711.3 ETN98446.1 - 0.75 8.3 7.2 0.97 7.9 5.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4611 PF15387.1 ETN98446.1 - 0.96 9.6 12.1 1.7 8.8 8.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Myc_N PF01056.13 ETN98446.1 - 1 8.4 6.8 1.3 8.1 4.7 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Sporozoite_P67 PF05642.6 ETN98446.1 - 1.3 6.7 9.2 1.5 6.5 6.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.7 ETN98446.1 - 1.3 8.2 6.0 1.9 7.6 4.2 1.2 1 0 0 1 1 1 0 NOA36 protein SspB PF04386.8 ETN98446.1 - 2.2 7.8 7.1 3.2 7.3 5.0 1.3 1 0 0 1 1 1 0 Stringent starvation protein B PBP1_TM PF14812.1 ETN98446.1 - 3.9 7.8 9.8 8.6 6.7 6.8 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WD40 PF00400.27 ETN98447.1 - 1e-19 69.5 0.3 1.2e-08 34.5 0.0 2.6 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETN98447.1 - 0.015 13.4 0.3 1.1 7.3 0.0 2.3 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETN98447.1 - 0.018 13.8 1.0 0.83 8.3 0.0 2.0 1 1 0 2 2 2 0 Nup133 N terminal like Herpes_gE PF02480.11 ETN98448.1 - 0.0042 15.4 1.3 0.0053 15.0 0.0 1.7 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E EGF PF00008.22 ETN98448.1 - 0.0049 16.8 8.6 0.0049 16.8 6.0 2.2 2 0 0 2 2 2 1 EGF-like domain CD34_antigen PF06365.7 ETN98448.1 - 0.023 14.3 0.3 0.56 9.8 0.1 2.2 1 1 1 2 2 2 0 CD34/Podocalyxin family Mid2 PF04478.7 ETN98448.1 - 0.026 13.9 2.4 0.028 13.8 0.2 2.0 3 0 0 3 3 3 0 Mid2 like cell wall stress sensor FTR1 PF03239.9 ETN98448.1 - 0.027 13.4 0.1 0.039 12.9 0.0 1.1 1 0 0 1 1 1 0 Iron permease FTR1 family EGF_2 PF07974.8 ETN98448.1 - 0.037 14.2 11.5 0.037 14.2 8.0 2.1 2 0 0 2 2 2 0 EGF-like domain SKG6 PF08693.5 ETN98448.1 - 0.074 12.3 0.4 0.13 11.5 0.3 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain hEGF PF12661.2 ETN98448.1 - 0.095 12.8 1.9 0.24 11.5 1.4 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF DUF2850 PF11012.3 ETN98448.1 - 0.14 12.3 0.2 1.2 9.3 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2850) Adeno_E3_CR2 PF02439.10 ETN98448.1 - 0.2 11.2 5.3 0.41 10.2 3.7 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF645 PF04875.7 ETN98449.1 - 0.00018 21.0 1.0 0.00039 20.0 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF645 Nuc_H_symport PF03825.11 ETN98449.1 - 0.029 13.1 0.0 0.037 12.7 0.0 1.1 1 0 0 1 1 1 0 Nucleoside H+ symporter PP_M1 PF03012.9 ETN98450.1 - 0.0017 17.7 5.2 0.0018 17.6 3.6 1.1 1 0 0 1 1 1 1 Phosphoprotein Nucleo_P87 PF07267.6 ETN98450.1 - 0.096 11.3 8.3 0.095 11.3 5.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Di19_C PF14571.1 ETN98450.1 - 1.1 9.5 9.8 1.6 9.0 6.3 1.6 1 1 1 2 2 2 0 Stress-induced protein Di19, C-terminal CDC45 PF02724.9 ETN98450.1 - 1.6 6.6 13.6 1.7 6.6 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Striatin PF08232.7 ETN98450.1 - 5.2 7.3 13.4 9.4 6.5 9.3 1.4 1 1 0 1 1 1 0 Striatin family DUF3537 PF12056.3 ETN98450.1 - 7.8 5.0 5.9 5.3 5.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3537) Filament PF00038.16 ETN98451.1 - 0.0093 15.4 23.9 0.73 9.2 0.1 2.5 1 1 1 2 2 2 2 Intermediate filament protein DUF4201 PF13870.1 ETN98451.1 - 0.014 14.8 7.0 0.014 14.8 4.9 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) Med4 PF10018.4 ETN98451.1 - 0.06 12.7 20.2 0.021 14.2 6.3 2.7 1 1 2 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 GAS PF13851.1 ETN98451.1 - 0.11 11.6 26.4 1.3 8.1 14.2 2.6 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding WEMBL PF05701.6 ETN98451.1 - 0.12 10.7 25.7 0.018 13.5 13.9 2.0 1 1 0 1 1 1 0 Weak chloroplast movement under blue light DASH_Dam1 PF08653.5 ETN98451.1 - 0.15 11.8 0.5 3.5 7.4 0.1 2.9 3 0 0 3 3 3 0 DASH complex subunit Dam1 MscS_porin PF12795.2 ETN98451.1 - 0.24 10.7 29.8 0.046 13.0 18.1 1.7 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain BLOC1_2 PF10046.4 ETN98451.1 - 0.43 10.7 21.6 2.8 8.1 1.9 4.2 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cytadhesin_P30 PF07271.6 ETN98451.1 - 1.5 8.0 6.9 2 7.6 4.8 1.3 1 0 0 1 1 1 0 Cytadhesin P30/P32 DUF641 PF04859.7 ETN98451.1 - 2 8.1 17.4 0.92 9.2 2.1 3.1 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Reo_sigmaC PF04582.7 ETN98451.1 - 2.1 7.4 6.6 5.9 5.9 3.6 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 ETN98451.1 - 2.3 8.5 14.6 3.5 7.9 0.2 4.1 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein FliD_N PF02465.13 ETN98451.1 - 3 8.2 17.8 5.4 7.4 0.1 4.0 2 2 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF972 PF06156.8 ETN98451.1 - 4.5 7.6 23.4 0.36 11.1 1.2 3.9 1 1 3 4 4 4 0 Protein of unknown function (DUF972) Laminin_II PF06009.7 ETN98451.1 - 6.5 6.5 18.8 0.18 11.5 1.2 3.1 2 1 2 4 4 4 0 Laminin Domain II Spc7 PF08317.6 ETN98451.1 - 8 5.0 25.7 5.2 5.6 9.2 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Ion_trans PF00520.26 ETN98453.1 - 5.4e-13 48.6 75.4 3.1e-12 46.1 20.3 6.7 5 3 1 6 6 6 3 Ion transport protein EphA2_TM PF14575.1 ETN98453.1 - 0.14 12.5 11.4 0.7 10.3 0.0 6.0 4 1 1 5 5 5 0 Ephrin type-A receptor 2 transmembrane domain RELT PF12606.3 ETN98453.1 - 1.8 7.8 0.0 1.8 7.8 0.0 4.9 5 0 0 5 5 5 0 Tumour necrosis factor receptor superfamily member 19 Cpn60_TCP1 PF00118.19 ETN98455.1 - 1.3e-37 129.5 0.2 1.6e-37 129.2 0.2 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Glyoxalase_3 PF13468.1 ETN98455.1 - 0.022 14.6 0.0 0.031 14.2 0.0 1.1 1 0 0 1 1 1 0 Glyoxalase-like domain DUF1510 PF07423.6 ETN98456.1 - 1.8e-06 27.4 4.4 2.9e-06 26.7 3.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) ASFV_J13L PF05568.6 ETN98456.1 - 2.1e-05 24.1 1.0 3e-05 23.6 0.7 1.3 1 0 0 1 1 1 1 African swine fever virus J13L protein PIG-U PF06728.8 ETN98456.1 - 0.00025 20.0 1.2 0.00028 19.8 0.8 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Peptidase_S49_N PF08496.5 ETN98456.1 - 0.00028 20.7 10.1 0.00036 20.3 7.0 1.2 1 0 0 1 1 1 1 Peptidase family S49 N-terminal Herpes_DNAp_acc PF04929.7 ETN98456.1 - 0.00081 18.4 0.7 0.00081 18.4 0.5 1.1 1 0 0 1 1 1 1 Herpes DNA replication accessory factor Ycf1 PF05758.7 ETN98456.1 - 0.0076 14.0 4.6 0.0089 13.8 3.2 1.0 1 0 0 1 1 1 1 Ycf1 DUF788 PF05620.6 ETN98456.1 - 0.037 13.8 8.6 0.068 13.0 5.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF788) Neur PF00064.13 ETN98456.1 - 0.072 11.1 2.5 0.1 10.6 1.7 1.3 1 0 0 1 1 1 0 Neuraminidase Peptidase_C37 PF05416.7 ETN98456.1 - 0.091 11.0 1.8 0.11 10.8 1.3 1.0 1 0 0 1 1 1 0 Southampton virus-type processing peptidase DUF1700 PF08006.6 ETN98456.1 - 0.3 10.3 8.3 0.5 9.6 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Tmemb_9 PF05434.6 ETN98456.1 - 0.37 10.5 11.0 0.58 9.8 7.6 1.5 1 1 0 1 1 1 0 TMEM9 Cytomega_TRL10 PF06084.6 ETN98456.1 - 0.62 9.8 4.0 0.96 9.2 2.8 1.5 1 1 0 1 1 1 0 Cytomegalovirus TRL10 protein Neur_chan_memb PF02932.11 ETN98456.1 - 2.3 8.0 10.3 7.6 6.3 7.2 1.9 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4446 PF14584.1 ETN98456.1 - 5.8 6.7 9.3 11 5.8 6.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) Shisa PF13908.1 ETN98456.1 - 6.6 6.8 10.6 0.57 10.3 3.9 1.7 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator eIF_4EBP PF05456.6 ETN98456.1 - 7.2 6.3 8.0 15 5.3 5.5 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) zf-TRAF PF02176.13 ETN98457.1 - 0.00014 22.1 1.7 0.00014 22.1 1.2 3.0 2 1 1 3 3 3 1 TRAF-type zinc finger Herpes_BLRF2 PF05812.7 ETN98457.1 - 0.012 15.4 8.3 3.1 7.6 5.8 2.3 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein FtsL PF04999.8 ETN98457.1 - 0.043 13.5 1.1 0.043 13.5 0.8 1.7 1 1 0 1 1 1 0 Cell division protein FtsL Rad50_zn_hook PF04423.9 ETN98457.1 - 0.048 13.1 2.2 8.4 5.9 0.1 3.4 3 0 0 3 3 3 0 Rad50 zinc hook motif DUF342 PF03961.8 ETN98457.1 - 0.058 11.8 3.5 0.085 11.2 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF972 PF06156.8 ETN98457.1 - 0.062 13.6 9.1 0.049 13.9 4.6 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF972) HALZ PF02183.13 ETN98457.1 - 0.16 11.7 4.6 0.1 12.3 1.1 2.2 1 1 1 2 2 2 0 Homeobox associated leucine zipper DUF3316 PF11777.3 ETN98457.1 - 0.18 11.5 2.6 0.24 11.1 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3316) AKAP7_RIRII_bdg PF10470.4 ETN98457.1 - 1.6 8.6 4.9 2.2 8.1 0.0 2.8 3 0 0 3 3 3 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein TSC22 PF01166.13 ETN98457.1 - 3.5 7.6 10.6 5.1 7.1 1.4 3.2 3 1 1 4 4 4 0 TSC-22/dip/bun family DivIC PF04977.10 ETN98457.1 - 4.4 6.8 10.6 0.5 9.8 2.6 2.4 1 1 1 2 2 2 0 Septum formation initiator WD40 PF00400.27 ETN98458.1 - 4.9e-11 42.0 1.9 7.2e-11 41.5 0.6 1.9 2 1 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETN98458.1 - 7.7e-05 21.0 0.2 7.7e-05 21.0 0.2 1.7 2 0 0 2 2 2 1 Nucleoporin Nup120/160 SopA_C PF13979.1 ETN98458.1 - 0.036 13.6 7.0 0.052 13.1 4.9 1.3 1 0 0 1 1 1 0 SopA-like catalytic domain DUF3373 PF11853.3 ETN98458.1 - 0.61 8.5 8.0 0.76 8.2 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Nup54 PF13874.1 ETN98458.1 - 1.1 8.9 10.4 1.6 8.4 7.2 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 LRS4 PF10422.4 ETN98458.1 - 1.3 8.3 15.1 1.8 7.8 10.5 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Peptidase_S76 PF13611.1 ETN98458.1 - 2.7 8.1 6.1 6.6 6.8 4.3 1.7 1 1 0 1 1 1 0 Serine peptidase of plant viral polyprotein, P1 AcylCoA_dehyd_C PF12186.3 ETN98458.1 - 2.9 7.7 6.7 1.1 9.1 1.3 2.1 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase C terminal Syntaxin PF00804.20 ETN98458.1 - 6 7.0 21.3 1.5 9.0 8.1 2.2 1 1 1 2 2 2 0 Syntaxin U-box PF04564.10 ETN98459.1 - 6.9e-05 22.7 0.4 0.00018 21.3 0.2 1.7 2 0 0 2 2 2 1 U-box domain CENP-F_leu_zip PF10473.4 ETN98460.1 - 0.01 15.7 35.3 0.04 13.7 6.5 3.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3355 PF11835.3 ETN98460.1 - 0.025 14.3 1.9 0.025 14.3 1.3 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF3355) DUF3618 PF12277.3 ETN98460.1 - 0.039 13.9 0.3 0.61 10.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) HALZ PF02183.13 ETN98460.1 - 0.13 12.0 0.2 0.13 12.0 0.1 3.8 3 1 0 3 3 3 0 Homeobox associated leucine zipper Snapin_Pallidin PF14712.1 ETN98460.1 - 0.18 12.1 25.4 0.4 11.0 4.7 4.2 1 1 3 4 4 4 0 Snapin/Pallidin Nup54 PF13874.1 ETN98460.1 - 0.24 11.0 27.2 0.3 10.7 4.9 2.3 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 Tropomyosin PF00261.15 ETN98460.1 - 0.31 10.0 30.7 3.3 6.7 21.3 2.4 1 1 0 1 1 1 0 Tropomyosin DUF342 PF03961.8 ETN98460.1 - 0.62 8.4 28.3 0.18 10.2 8.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF342) AAA_13 PF13166.1 ETN98460.1 - 0.72 8.2 32.2 9.9 4.4 22.3 2.0 1 1 0 1 1 1 0 AAA domain IncA PF04156.9 ETN98460.1 - 0.94 9.0 41.4 0.76 9.3 13.8 2.1 1 1 0 2 2 2 0 IncA protein Filament PF00038.16 ETN98460.1 - 3.3 7.1 35.4 4.5 6.6 12.3 2.6 2 1 0 2 2 2 0 Intermediate filament protein Pox_A_type_inc PF04508.7 ETN98460.1 - 4.9 7.2 11.2 4.8 7.2 0.1 4.8 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat DUF1664 PF07889.7 ETN98460.1 - 6 6.6 19.6 3.6 7.4 2.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF3584 PF12128.3 ETN98460.1 - 7.3 3.7 36.2 1.2 6.4 14.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Tautomerase_2 PF14552.1 ETN98460.1 - 9.2 6.3 7.3 5.2 7.1 1.0 3.0 2 2 0 3 3 3 0 Tautomerase enzyme Ank_2 PF12796.2 ETN98461.1 - 9.7e-12 45.0 0.1 0.0001 22.5 0.0 2.2 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETN98461.1 - 2.4e-09 36.5 0.0 4.8e-05 22.9 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 ETN98461.1 - 3.7e-08 33.3 0.0 0.00017 21.7 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETN98461.1 - 1.2e-07 32.0 0.0 0.0016 18.9 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETN98461.1 - 7.4e-07 28.8 0.0 0.00044 20.2 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Lebercilin PF15619.1 ETN98461.1 - 0.02 14.3 0.9 0.02 14.3 0.6 1.6 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease bZIP_1 PF00170.16 ETN98461.1 - 0.12 12.3 0.3 0.12 12.3 0.2 1.9 2 0 0 2 2 2 0 bZIP transcription factor DUF3788 PF12663.2 ETN98461.1 - 2.9 7.5 5.8 6.2 6.5 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3788) AlcCBM31 PF11606.3 ETN98462.1 - 0.18 11.7 1.3 0.31 11.0 0.1 2.0 2 1 0 2 2 2 0 Family 31 carbohydrate binding protein Lebercilin PF15619.1 ETN98463.1 - 0.0054 16.1 18.2 0.035 13.5 3.1 2.9 1 1 1 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease She9_MDM33 PF05546.6 ETN98463.1 - 0.0065 16.0 8.3 0.17 11.4 0.3 2.1 2 0 0 2 2 2 2 She9 / Mdm33 family DNA_pol_lambd_f PF10391.4 ETN98463.1 - 0.021 14.3 1.1 1.8 8.1 0.0 2.9 3 0 0 3 3 3 0 Fingers domain of DNA polymerase lambda HLH PF00010.21 ETN98463.1 - 0.026 14.2 2.5 3 7.6 0.1 3.2 1 1 1 2 2 2 0 Helix-loop-helix DNA-binding domain Glutaredoxin2_C PF04399.8 ETN98463.1 - 0.072 12.6 4.0 1.5 8.4 0.1 2.9 1 1 2 3 3 3 0 Glutaredoxin 2, C terminal domain Exonuc_VII_L PF02601.10 ETN98463.1 - 0.15 11.2 8.6 0.18 10.9 5.9 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Bacillus_HBL PF05791.6 ETN98463.1 - 0.64 9.3 9.8 0.086 12.2 2.9 1.9 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) CorA PF01544.13 ETN98463.1 - 0.86 8.5 6.0 0.98 8.3 0.3 2.3 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Baculo_p24 PF05073.7 ETN98463.1 - 1.1 8.8 7.9 0.48 9.9 2.3 2.2 1 1 0 2 2 2 0 Baculovirus P24 capsid protein YopD PF05844.7 ETN98463.1 - 1.7 7.5 7.7 0.17 10.9 1.2 2.0 2 0 0 2 2 2 0 YopD protein DUF4404 PF14357.1 ETN98463.1 - 3 8.3 8.3 15 6.1 1.9 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) Spc7 PF08317.6 ETN98463.1 - 3.7 6.1 18.2 0.046 12.3 5.9 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Rho_Binding PF08912.6 ETN98463.1 - 4.5 7.6 20.8 0.22 11.8 3.7 3.6 2 1 0 2 2 2 0 Rho Binding GP41 PF00517.12 ETN98463.1 - 5.7 6.4 9.0 0.81 9.2 0.7 2.3 1 1 1 2 2 2 0 Retroviral envelope protein BLOC1_2 PF10046.4 ETN98463.1 - 7 6.8 13.4 4.2 7.5 2.4 2.8 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF501 PF04417.7 ETN98464.1 - 0.073 12.9 5.1 3 7.7 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF501) Baculo_PEP_C PF04513.7 ETN98464.1 - 8.9 6.1 11.6 40 4.0 0.0 4.6 5 0 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pox_Ag35 PF03286.9 ETN98465.1 - 0.15 11.6 5.6 0.16 11.5 3.9 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Spb1_C PF07780.7 ETN98465.1 - 0.39 10.1 9.7 0.41 10.1 6.7 1.0 1 0 0 1 1 1 0 Spb1 C-terminal domain SR-25 PF10500.4 ETN98465.1 - 0.46 9.9 8.2 0.46 9.9 5.7 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DBD_Tnp_Mut PF03108.10 ETN98469.1 - 0.051 13.1 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 MuDR family transposase GP40 PF11025.3 ETN98469.1 - 0.22 11.0 2.5 0.24 10.9 1.8 1.1 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium Fib_alpha PF08702.5 ETN98470.1 - 0.011 15.9 15.0 0.045 13.8 10.4 2.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family PP2C_C PF07830.8 ETN98470.1 - 0.023 14.7 1.3 0.089 12.9 0.9 2.0 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain DUF479 PF04336.7 ETN98470.1 - 0.027 14.5 1.3 0.027 14.5 0.9 2.6 2 1 1 3 3 3 0 Protein of unknown function, DUF479 Glyco_hydro_67N PF03648.9 ETN98470.1 - 0.068 13.2 2.9 0.17 11.8 2.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 N-terminus DUF1053 PF06327.9 ETN98470.1 - 0.21 11.9 4.3 0.6 10.4 2.9 1.9 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) Peptidase_C14 PF00656.17 ETN98471.1 - 1.2e-06 28.4 0.1 2.1e-06 27.6 0.0 1.4 1 1 0 1 1 1 1 Caspase domain Amdo_NSP PF12475.3 ETN98472.1 - 0.032 14.1 1.3 0.067 13.1 0.9 1.5 1 0 0 1 1 1 0 Amdovirus non-structural protein PyrI_C PF02748.10 ETN98472.1 - 0.051 13.0 0.1 0.12 11.8 0.1 1.6 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-3CxxC PF13695.1 ETN98472.1 - 0.2 11.9 1.7 0.33 11.2 1.2 1.6 1 1 0 1 1 1 0 Zinc-binding domain Epimerase_Csub PF13950.1 ETN98472.1 - 0.32 10.9 1.5 0.96 9.4 0.0 2.4 3 0 0 3 3 3 0 UDP-glucose 4-epimerase C-term subunit DUF4187 PF13821.1 ETN98474.1 - 0.85 9.2 4.0 0.26 10.8 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) SAP30_Sin3_bdg PF13867.1 ETN98475.1 - 0.00063 19.5 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 NAAA-beta PF15508.1 ETN98475.1 - 0.076 13.3 0.1 0.3 11.4 0.0 1.8 1 1 1 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase YwhD PF08741.5 ETN98475.1 - 0.12 11.8 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 YwhD family Gly-zipper_OmpA PF13436.1 ETN98476.1 - 0.00013 21.5 9.8 0.00026 20.6 6.8 1.4 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain IncA PF04156.9 ETN98476.1 - 0.00074 19.1 2.9 0.0014 18.2 2.0 1.5 1 1 0 1 1 1 1 IncA protein Gly-zipper_YMGG PF13441.1 ETN98476.1 - 0.0024 17.3 29.9 0.0052 16.2 20.7 1.6 1 1 0 1 1 1 1 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.1 ETN98476.1 - 0.0048 16.4 26.4 0.05 13.2 18.4 2.1 1 1 0 1 1 1 1 Glycine zipper DUF3829 PF12889.2 ETN98476.1 - 0.008 15.4 10.3 0.049 12.8 6.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3829) DUF4307 PF14155.1 ETN98476.1 - 0.021 14.5 0.7 0.2 11.4 0.0 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4307) DUF937 PF06078.6 ETN98476.1 - 0.033 14.4 0.2 0.054 13.7 0.2 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF937) Rick_17kDa_Anti PF05433.10 ETN98476.1 - 0.05 13.2 28.0 0.11 12.1 19.4 1.6 1 1 0 1 1 1 0 Glycine zipper 2TM domain EMP24_GP25L PF01105.19 ETN98476.1 - 0.062 13.0 6.9 0.12 12.0 4.8 1.6 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DivIC PF04977.10 ETN98476.1 - 0.093 12.2 3.6 0.31 10.5 2.5 2.0 1 0 0 1 1 1 0 Septum formation initiator DUF919 PF06034.6 ETN98476.1 - 0.56 9.8 12.1 0.3 10.7 1.9 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Seryl_tRNA_N PF02403.17 ETN98476.1 - 2.1 8.4 14.5 3.8 7.5 7.9 2.6 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FliD_N PF02465.13 ETN98476.1 - 4.1 7.8 7.5 13 6.2 1.7 2.9 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus V_ATPase_I PF01496.14 ETN98476.1 - 4.7 4.9 10.9 8.4 4.0 7.2 1.5 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Transgly_assoc PF04226.8 ETN98476.1 - 5.4 7.1 18.9 2.2 8.4 8.9 2.1 2 0 0 2 2 2 0 Transglycosylase associated protein Romo1 PF10247.4 ETN98476.1 - 5.4 7.2 12.3 1.2 9.3 1.0 2.3 1 1 1 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 TPR_12 PF13424.1 ETN98477.1 - 0.022 14.6 0.0 0.027 14.3 0.0 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Lipoprotein_3 PF00938.12 ETN98477.1 - 0.034 13.8 0.2 0.047 13.4 0.2 1.2 1 0 0 1 1 1 0 Lipoprotein DUF1623 PF07785.6 ETN98477.1 - 0.047 13.6 0.5 0.057 13.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1623) Peptidase_C14 PF00656.17 ETN98478.1 - 1.3e-06 28.3 0.4 2.4e-06 27.4 0.3 1.4 1 0 0 1 1 1 1 Caspase domain SAM_1 PF00536.25 ETN98479.1 - 4.8e-10 39.4 0.1 8.1e-10 38.7 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETN98479.1 - 1.1e-08 34.8 0.1 1.8e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) ARGLU PF15346.1 ETN98479.1 - 0.019 14.7 1.7 0.019 14.7 1.2 1.9 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 Imm15 PF15590.1 ETN98479.1 - 0.12 11.4 1.0 0.25 10.4 0.7 1.5 1 0 0 1 1 1 0 Immunity protein 15 HTH_36 PF13730.1 ETN98479.1 - 0.14 12.3 0.1 0.5 10.5 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain EURL PF06937.6 ETN98479.1 - 0.18 11.2 2.7 0.26 10.6 1.9 1.2 1 0 0 1 1 1 0 EURL protein Asp-B-Hydro_N PF05279.6 ETN98479.1 - 0.73 9.6 4.9 0.95 9.2 3.4 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region HTH_44 PF14641.1 ETN98480.1 - 0.0098 15.8 1.3 0.013 15.4 0.3 1.6 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 DUF4485 PF14846.1 ETN98480.1 - 0.012 15.3 0.1 0.015 14.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) DUF4162 PF13732.1 ETN98480.1 - 0.098 13.1 0.3 0.19 12.2 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4162) IL1_propep PF02394.11 ETN98483.1 - 4.7 7.6 7.5 1.6 9.1 2.8 2.0 2 0 0 2 2 2 0 Interleukin-1 propeptide HAUS-augmin3 PF14932.1 ETN98484.1 - 0.069 12.3 18.1 0.09 11.9 12.5 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 MxiH PF09392.5 ETN98484.1 - 0.095 13.2 0.3 0.15 12.6 0.2 1.4 1 1 0 1 1 1 0 Type III secretion needle MxiH like DUF972 PF06156.8 ETN98484.1 - 0.92 9.8 15.0 2.4 8.5 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) FixO PF02433.10 ETN98484.1 - 1 8.6 4.3 0.99 8.7 2.4 1.5 1 1 1 2 2 2 0 Cytochrome C oxidase, mono-heme subunit/FixO SlyX PF04102.7 ETN98484.1 - 3.4 8.0 16.5 0.86 10.0 2.1 3.0 3 0 0 3 3 3 0 SlyX Nnf1 PF03980.9 ETN98484.1 - 4 7.4 16.8 22 5.0 11.7 2.0 1 1 0 1 1 1 0 Nnf1 IFP_35_N PF07334.8 ETN98484.1 - 8.2 6.4 8.9 0.64 10.0 1.3 2.4 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus S-AdoMet_synt_C PF02773.11 ETN98485.1 - 3.3e-73 243.9 0.0 5.4e-73 243.2 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 ETN98485.1 - 1.7e-47 160.3 0.1 3.3e-47 159.3 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 ETN98485.1 - 7.4e-40 135.2 0.3 1.4e-39 134.3 0.2 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain DUF2312 PF10073.4 ETN98485.1 - 0.14 11.4 0.2 0.36 10.2 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF2714 PF10896.3 ETN98486.1 - 0.015 15.1 1.2 0.015 15.1 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2714) ATP13 PF12921.2 ETN98486.1 - 0.08 12.2 0.1 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ATPase expression Stn1 PF10451.4 ETN98487.1 - 0.13 11.0 0.3 0.22 10.3 0.2 1.3 1 0 0 1 1 1 0 Telomere regulation protein Stn1 CMV_US PF08001.6 ETN98489.1 - 0.51 9.3 2.9 2.2 7.2 0.0 2.0 1 1 1 2 2 2 0 CMV US Sec62 PF03839.11 ETN98489.1 - 0.55 9.5 9.2 0.57 9.5 6.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 NARP1 PF12569.3 ETN98489.1 - 0.56 8.9 12.9 0.62 8.7 8.9 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CDC45 PF02724.9 ETN98489.1 - 4.1 5.3 9.8 4.5 5.1 6.8 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2201_N PF13203.1 ETN98489.1 - 5.7 6.0 9.0 6 5.9 6.2 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain WD40 PF00400.27 ETN98490.1 - 0.063 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 WD domain, G-beta repeat Pentapeptide PF00805.17 ETN98490.1 - 0.076 12.2 0.1 4.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Pentapeptide repeats (8 copies) WD40 PF00400.27 ETN98492.1 - 4.1e-39 131.0 5.2 4.8e-10 38.9 0.2 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETN98492.1 - 8e-09 34.1 1.0 0.022 12.9 0.0 4.0 2 1 2 4 4 4 3 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETN98492.1 - 5.2e-06 26.7 7.7 6.3e-06 26.4 2.3 2.8 1 1 1 2 2 2 1 TRAF-type zinc finger F5_F8_type_C PF00754.20 ETN98493.1 - 0.0043 16.8 0.1 0.0066 16.2 0.0 1.4 1 1 0 1 1 1 1 F5/8 type C domain Sad1_UNC PF07738.8 ETN98493.1 - 0.15 11.8 0.1 18 5.1 0.0 2.2 2 0 0 2 2 2 0 Sad1 / UNC-like C-terminal Kelch_6 PF13964.1 ETN98494.1 - 2.3e-06 27.5 0.6 0.0059 16.7 0.0 3.4 2 1 1 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETN98494.1 - 4.8e-06 26.2 0.2 0.044 13.5 0.0 3.1 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETN98494.1 - 5.2e-06 25.9 3.5 0.00053 19.4 0.0 3.4 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 ETN98494.1 - 0.0017 18.0 0.8 0.069 12.9 0.0 3.2 3 1 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 ETN98494.1 - 0.018 15.1 0.1 0.31 11.2 0.0 2.8 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_5 PF13854.1 ETN98494.1 - 0.03 14.2 0.4 14 5.8 0.0 3.1 4 0 0 4 4 4 0 Kelch motif WD40 PF00400.27 ETN98497.1 - 4.5e-09 35.8 0.4 0.008 16.0 0.0 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat eIF2A PF08662.6 ETN98497.1 - 6.6e-07 29.2 1.4 0.56 9.8 0.1 3.6 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETN98497.1 - 5.4e-05 22.7 0.7 6.2 6.6 0.0 4.9 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETN98497.1 - 0.00046 19.0 0.8 0.23 10.1 0.0 3.2 1 1 1 2 2 2 2 Nup133 N terminal like Coatomer_WDAD PF04053.9 ETN98497.1 - 0.013 14.2 0.4 2.4 6.8 0.3 2.8 2 1 0 2 2 2 0 Coatomer WD associated region PQQ_2 PF13360.1 ETN98497.1 - 0.048 13.1 0.0 0.57 9.5 0.0 2.4 1 1 0 1 1 1 0 PQQ-like domain Proteasome_A_N PF10584.4 ETN98497.1 - 0.068 12.5 3.8 8.3 5.8 0.1 4.7 6 1 0 6 6 6 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 ETN98498.1 - 1.1e-34 117.0 15.5 2.2e-10 39.9 0.2 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETN98498.1 - 0.00082 17.6 0.3 0.62 8.1 0.0 3.1 2 2 0 3 3 3 2 Nucleoporin Nup120/160 Methyltransf_25 PF13649.1 ETN98498.1 - 0.1 12.9 0.0 0.34 11.2 0.0 1.9 3 0 0 3 3 3 0 Methyltransferase domain PPR_2 PF13041.1 ETN98499.1 - 1.7e-10 40.6 1.5 8.8e-05 22.4 0.2 2.4 2 0 0 2 2 2 2 PPR repeat family PPR PF01535.15 ETN98499.1 - 5.9e-09 35.3 0.2 0.0024 17.7 0.0 2.6 2 0 0 2 2 2 2 PPR repeat PPR_1 PF12854.2 ETN98499.1 - 4.2e-06 26.1 0.1 0.037 13.5 0.0 2.2 2 0 0 2 2 2 2 PPR repeat PPR_3 PF13812.1 ETN98499.1 - 2.8e-05 24.0 0.0 0.026 14.7 0.0 3.0 3 0 0 3 3 3 2 Pentatricopeptide repeat domain Prok-E2_E PF14462.1 ETN98500.1 - 0.049 13.2 0.5 0.059 12.9 0.4 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family E DinB PF05163.7 ETN98500.1 - 0.077 12.6 0.6 0.092 12.4 0.4 1.1 1 0 0 1 1 1 0 DinB family Phage_CII PF05269.6 ETN98500.1 - 0.094 12.7 0.1 0.12 12.4 0.0 1.4 1 1 0 1 1 1 0 Bacteriophage CII protein KilA-N PF04383.8 ETN98500.1 - 6.2 6.4 8.1 12 5.5 5.6 1.5 1 1 0 1 1 1 0 KilA-N domain DUF972 PF06156.8 ETN98501.1 - 0.00064 20.0 7.3 0.0013 19.0 5.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF972) zf-TRAF PF02176.13 ETN98501.1 - 0.014 15.7 3.3 0.014 15.7 1.1 2.0 2 0 0 2 2 2 0 TRAF-type zinc finger IncA PF04156.9 ETN98501.1 - 0.39 10.2 5.2 0.49 9.9 3.6 1.1 1 0 0 1 1 1 0 IncA protein Herpes_BLRF2 PF05812.7 ETN98501.1 - 0.46 10.3 9.2 0.68 9.7 6.4 1.3 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein DivIC PF04977.10 ETN98501.1 - 1.3 8.5 12.5 0.11 12.0 4.6 1.9 1 1 1 2 2 2 0 Septum formation initiator AAA_23 PF13476.1 ETN98501.1 - 6.5 7.0 14.6 11 6.3 10.2 1.5 1 1 0 1 1 1 0 AAA domain Geminin PF07412.7 ETN98502.1 - 0.062 12.9 13.2 0.045 13.4 7.2 1.8 1 1 1 2 2 2 0 Geminin DUF641 PF04859.7 ETN98502.1 - 0.43 10.3 6.7 0.45 10.2 4.6 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) UPF0515 PF15135.1 ETN98502.1 - 1.9 7.5 4.7 1.9 7.4 3.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 Cep57_MT_bd PF06657.8 ETN98502.1 - 1.9 8.5 10.0 3.3 7.7 0.9 2.1 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 GLE1 PF07817.8 ETN98502.1 - 2.6 6.9 7.6 2.4 7.0 5.3 1.0 1 0 0 1 1 1 0 GLE1-like protein Vfa1 PF08432.5 ETN98502.1 - 3.2 7.7 13.9 3.6 7.5 9.7 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SseC PF04888.7 ETN98502.1 - 4.1 6.6 14.8 4.1 6.6 10.3 1.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF4337 PF14235.1 ETN98502.1 - 8 6.2 8.5 7.9 6.2 5.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) RAP1 PF07218.6 ETN98502.1 - 9.4 4.1 12.9 9.9 4.1 8.9 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) WD40 PF00400.27 ETN98503.1 - 5.3e-25 86.3 6.7 7.4e-11 41.5 0.1 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN98503.1 - 0.00017 19.9 1.7 0.75 7.8 0.0 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 UpxZ PF06603.6 ETN98503.1 - 0.03 14.3 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 UpxZ family of transcription anti-terminator antagonists Ricin_B_lectin PF00652.17 ETN98503.1 - 0.032 14.2 5.1 1.1 9.3 1.1 2.5 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain HAD PF12710.2 ETN98503.1 - 0.12 12.5 0.1 0.27 11.3 0.1 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Leo1 PF04004.8 ETN98505.1 - 3.3e-23 82.2 0.3 9.8e-23 80.7 0.2 1.8 1 1 0 1 1 1 1 Leo1-like protein EF1G PF00647.14 ETN98505.1 - 0.0066 16.1 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain UPF0302 PF08864.5 ETN98505.1 - 0.1 12.4 1.3 0.26 11.1 0.1 2.2 2 1 0 2 2 2 0 UPF0302 domain zf-UBP PF02148.14 ETN98506.1 - 7.6e-10 38.7 0.2 4.9e-09 36.1 0.0 2.1 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein FAD_syn PF06574.7 ETN98506.1 - 0.045 13.3 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 FAD synthetase Kelch_6 PF13964.1 ETN98507.1 - 0.00015 21.8 4.1 0.25 11.5 0.1 4.6 4 1 2 6 6 6 2 Kelch motif Kelch_5 PF13854.1 ETN98507.1 - 0.00016 21.5 4.8 0.82 9.7 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETN98507.1 - 0.0015 18.2 1.4 0.86 9.4 0.0 4.2 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETN98507.1 - 0.01 15.5 3.0 2.5 8.0 0.0 3.6 4 0 0 4 4 4 0 Kelch motif Kelch_1 PF01344.20 ETN98507.1 - 0.013 15.0 0.6 12 5.4 0.1 3.6 3 0 0 3 3 3 0 Kelch motif FliP PF00813.15 ETN98508.1 - 0.11 12.1 0.8 0.17 11.5 0.5 1.2 1 0 0 1 1 1 0 FliP family Nup88 PF10168.4 ETN98508.1 - 0.13 10.0 10.1 0.17 9.7 7.0 1.0 1 0 0 1 1 1 0 Nuclear pore component V_ATPase_I PF01496.14 ETN98508.1 - 1.7 6.4 5.0 1.9 6.2 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FliT PF05400.8 ETN98508.1 - 4.7 7.6 13.4 7.9 6.9 9.3 1.3 1 0 0 1 1 1 0 Flagellar protein FliT DUF1878 PF08963.5 ETN98510.1 - 0.072 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1878) TPR_12 PF13424.1 ETN98512.1 - 7.2e-17 61.1 7.5 4.1e-11 42.6 0.2 2.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETN98512.1 - 5.2e-16 57.4 12.1 1.4e-05 24.4 0.6 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETN98512.1 - 1.3e-13 49.6 1.1 0.00032 20.2 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETN98512.1 - 1.7e-13 49.9 12.4 3e-08 33.1 1.3 2.4 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 ETN98512.1 - 1.8e-12 46.1 8.4 0.00045 19.9 0.2 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETN98512.1 - 7.3e-12 44.1 11.8 0.00033 20.2 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat MIT PF04212.13 ETN98512.1 - 1.7e-06 27.7 5.7 0.034 14.0 0.2 3.2 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 ETN98512.1 - 1.7e-05 24.9 0.8 0.26 11.8 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETN98512.1 - 9.2e-05 22.2 0.0 0.43 10.5 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETN98512.1 - 0.0025 18.3 0.0 14 6.6 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETN98512.1 - 0.0028 18.2 0.2 8.9 7.1 0.0 3.2 1 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 ETN98512.1 - 0.05 13.8 1.4 3.8 7.9 0.1 3.9 2 2 1 3 3 3 0 Tetratricopeptide repeat Rapamycin_bind PF08771.6 ETN98512.1 - 0.1 12.6 0.0 0.26 11.4 0.0 1.6 2 0 0 2 2 2 0 Rapamycin binding domain SHNi-TPR PF10516.4 ETN98512.1 - 0.3 10.3 1.7 2.5 7.4 0.1 2.8 3 0 0 3 3 3 0 SHNi-TPR TPR_19 PF14559.1 ETN98512.1 - 0.77 10.1 3.7 17 5.8 0.1 2.6 3 0 0 3 3 2 0 Tetratricopeptide repeat Sel1 PF08238.7 ETN98512.1 - 0.8 10.4 3.6 5.1 7.8 0.3 2.9 3 0 0 3 3 3 0 Sel1 repeat Apc3 PF12895.2 ETN98512.1 - 1.2 9.3 6.6 27 4.9 4.0 3.1 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 NSF PF02071.15 ETN98512.1 - 4.1 8.4 7.1 97 4.2 0.1 4.6 5 1 1 6 6 5 0 Aromatic-di-Alanine (AdAR) repeat PCI PF01399.22 ETN98513.1 - 0.00092 19.4 0.1 0.0017 18.6 0.1 1.6 1 1 0 1 1 1 1 PCI domain ACDC PF14733.1 ETN98513.1 - 0.019 15.0 0.2 0.036 14.1 0.1 1.5 1 0 0 1 1 1 0 AP2-coincident C-terminal CUE PF02845.11 ETN98513.1 - 0.092 12.2 0.2 0.092 12.2 0.1 2.5 3 0 0 3 3 3 0 CUE domain PUB PF09409.5 ETN98514.1 - 0.096 12.4 1.4 0.54 10.0 1.0 2.0 1 1 0 1 1 1 0 PUB domain HSP90 PF00183.13 ETN98516.1 - 3.6e-54 184.0 15.1 4.4e-34 117.7 1.1 2.0 1 1 1 2 2 2 2 Hsp90 protein CutA1 PF03091.10 ETN98516.1 - 0.016 14.8 0.2 0.034 13.8 0.2 1.6 1 1 0 1 1 1 0 CutA1 divalent ion tolerance protein Ste50p-SAM PF09235.5 ETN98516.1 - 0.039 13.9 0.3 0.13 12.3 0.1 2.0 2 0 0 2 2 2 0 Ste50p, sterile alpha motif HSP90 PF00183.13 ETN98517.1 - 1.6e-14 53.1 1.4 3.4e-14 52.1 0.9 1.6 1 1 0 1 1 1 1 Hsp90 protein Adeno_E3_15_3 PF03307.9 ETN98517.1 - 0.013 15.2 4.7 0.031 14.0 3.1 1.7 1 1 1 2 2 2 0 Adenovirus 15.3kD protein in E3 region DUF4492 PF14899.1 ETN98517.1 - 0.056 12.9 0.8 0.15 11.6 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) DUF1768 PF08719.6 ETN98517.1 - 0.75 9.5 4.1 0.98 9.1 2.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1768) RelA_SpoT PF04607.12 ETN98518.1 - 0.0079 16.1 3.8 0.0081 16.1 0.2 2.2 2 1 0 2 2 2 1 Region found in RelA / SpoT proteins Pkinase PF00069.20 ETN98519.1 - 7.1e-36 123.6 0.8 8.3e-36 123.4 0.6 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETN98519.1 - 3.9e-18 65.4 0.1 4.5e-18 65.2 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETN98519.1 - 0.00035 19.6 0.0 0.00068 18.7 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETN98519.1 - 0.086 12.5 0.0 0.14 11.8 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family DASH_Dad3 PF08656.5 ETN98521.1 - 0.011 15.4 0.4 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 DASH complex subunit Dad3 Nipped-B_C PF12830.2 ETN98521.1 - 0.051 13.2 0.1 0.1 12.2 0.1 1.5 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus Pil1 PF13805.1 ETN98522.1 - 0.041 13.0 0.7 0.049 12.7 0.5 1.0 1 0 0 1 1 1 0 Eisosome component PIL1 DUF2951 PF11166.3 ETN98522.1 - 0.17 11.7 1.4 0.27 11.1 1.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2951) DNA_pol_A PF00476.15 ETN98523.1 - 4.5e-08 32.1 0.0 3.9e-07 29.0 0.0 2.2 1 1 1 2 2 2 1 DNA polymerase family A DNA_pol3_a_NI PF14480.1 ETN98523.1 - 0.081 12.5 0.3 0.081 12.5 0.2 2.9 4 0 0 4 4 4 0 DNA polymerase III polC-type N-terminus I DNA_pol_A PF00476.15 ETN98524.1 - 0.077 11.5 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 ETN98524.1 - 0.11 11.9 0.2 0.31 10.5 0.0 1.8 2 0 0 2 2 2 0 3'-5' exonuclease ACT_5 PF13710.1 ETN98525.1 - 0.16 11.8 0.4 1.8 8.4 0.1 2.6 1 1 1 2 2 2 0 ACT domain WD40 PF00400.27 ETN98526.1 - 2.1e-22 78.1 3.9 4.9e-08 32.5 0.0 3.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN98526.1 - 0.00048 18.3 1.8 0.75 7.8 0.1 3.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETN98526.1 - 0.023 13.4 2.1 0.13 11.0 1.5 2.2 1 1 0 1 1 1 0 Nup133 N terminal like WD40 PF00400.27 ETN98527.1 - 1.8e-37 125.8 2.1 2.6e-13 49.2 0.2 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN98527.1 - 0.0013 16.9 0.6 0.0053 14.9 0.4 1.9 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Str_synth PF03088.11 ETN98527.1 - 0.011 15.7 0.1 0.051 13.6 0.0 2.2 2 1 1 3 3 3 0 Strictosidine synthase Nucleoporin_N PF08801.6 ETN98527.1 - 0.023 13.4 1.0 0.18 10.5 0.1 2.4 1 1 1 2 2 2 0 Nup133 N terminal like AAA PF00004.24 ETN98528.1 - 5.1e-10 39.6 0.0 0.00018 21.7 0.0 3.6 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETN98528.1 - 1.4e-07 31.2 0.3 0.0026 17.4 0.0 4.3 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETN98528.1 - 2.2e-06 27.8 0.0 0.29 11.2 0.0 4.2 3 1 0 3 3 3 2 AAA domain IstB_IS21 PF01695.12 ETN98528.1 - 0.00029 20.2 0.3 0.16 11.3 0.0 3.6 4 0 0 4 4 4 1 IstB-like ATP binding protein DUF258 PF03193.11 ETN98528.1 - 0.00054 19.1 0.0 0.002 17.3 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 ETN98528.1 - 0.00082 19.4 0.1 0.072 13.0 0.0 3.3 3 1 0 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 ETN98528.1 - 0.0013 18.6 3.8 0.04 13.8 0.0 4.2 5 0 0 5 5 5 1 AAA domain ABC_tran PF00005.22 ETN98528.1 - 0.0013 19.0 1.4 0.0092 16.2 0.0 3.0 3 0 0 3 3 2 1 ABC transporter DUF815 PF05673.8 ETN98528.1 - 0.0019 17.2 0.2 0.0072 15.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.1 ETN98528.1 - 0.0031 17.5 0.5 0.2 11.7 0.0 3.9 5 1 0 5 5 5 1 Sigma-54 interaction domain PduV-EutP PF10662.4 ETN98528.1 - 0.0053 16.2 0.9 0.043 13.3 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation CobA_CobO_BtuR PF02572.10 ETN98528.1 - 0.014 14.9 0.0 0.17 11.4 0.0 2.6 3 0 0 3 3 3 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP RNA_helicase PF00910.17 ETN98528.1 - 0.031 14.4 0.2 2.6 8.2 0.0 3.4 2 1 0 2 2 2 0 RNA helicase NACHT PF05729.7 ETN98528.1 - 0.04 13.5 2.6 1.2 8.7 0.1 3.3 4 0 0 4 4 3 0 NACHT domain Mg_chelatase PF01078.16 ETN98528.1 - 0.054 12.6 0.1 16 4.5 0.0 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 ETN98528.1 - 0.073 12.5 0.0 0.88 9.0 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain T2SE PF00437.15 ETN98528.1 - 0.086 11.7 0.0 1.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein MCM PF00493.18 ETN98528.1 - 0.11 11.2 4.4 2.5 6.7 0.0 3.7 4 1 0 4 4 4 0 MCM2/3/5 family Arch_ATPase PF01637.13 ETN98528.1 - 0.2 11.3 9.0 0.33 10.5 0.1 3.8 3 1 1 4 4 4 0 Archaeal ATPase Peptidase_S49_N PF08496.5 ETN98528.1 - 0.46 10.2 7.2 1.5 8.6 4.5 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal LRAT PF04970.8 ETN98530.1 - 0.091 12.7 0.1 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 Lecithin retinol acyltransferase UCH PF00443.24 ETN98531.1 - 4.2e-07 29.3 3.5 8.5e-07 28.3 2.4 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Methyltransf_5 PF01795.14 ETN98531.1 - 0.045 13.0 0.1 0.075 12.2 0.1 1.2 1 0 0 1 1 1 0 MraW methylase family HEAT_2 PF13646.1 ETN98533.1 - 4.4e-11 42.9 0.0 0.00087 19.5 0.0 5.4 3 1 2 6 6 6 4 HEAT repeats HEAT PF02985.17 ETN98533.1 - 6.5e-10 38.2 0.0 2.8 8.2 0.0 8.6 9 0 0 9 9 9 1 HEAT repeat HEAT_EZ PF13513.1 ETN98533.1 - 0.0002 21.7 0.0 12 6.5 0.0 5.1 4 1 1 5 5 5 2 HEAT-like repeat Cytochrom_C PF00034.16 ETN98533.1 - 0.048 14.4 0.0 78 4.1 0.0 4.2 5 0 0 5 5 5 0 Cytochrome c N_Asn_amidohyd PF14736.1 ETN98533.1 - 0.16 10.8 6.0 0.41 9.4 0.1 3.7 3 1 0 4 4 4 0 Protein N-terminal asparagine amidohydrolase P16-Arc PF04699.9 ETN98533.1 - 0.52 10.3 11.7 0.49 10.4 0.1 4.9 4 2 1 5 5 5 0 ARP2/3 complex 16 kDa subunit (p16-Arc) DUF2435 PF10363.4 ETN98533.1 - 1.9 8.4 22.3 0.23 11.3 0.5 6.3 5 1 2 7 7 7 0 Protein of unknown function (DUF2435) Rota_NS26 PF01525.11 ETN98535.1 - 0.018 14.8 0.8 0.02 14.6 0.6 1.1 1 0 0 1 1 1 0 Rotavirus NS26 SRP19 PF01922.12 ETN98535.1 - 0.087 13.4 0.1 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 SRP19 protein WD40 PF00400.27 ETN98536.1 - 2.2e-14 52.6 0.2 1.8e-12 46.5 0.0 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat Kelch_1 PF01344.20 ETN98536.1 - 4.8e-11 42.0 2.4 4.4e-06 26.1 0.1 2.6 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.1 ETN98536.1 - 2.4e-07 30.6 0.5 0.0078 16.3 0.0 2.6 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 ETN98536.1 - 1.4e-06 27.9 0.1 0.031 14.0 0.0 2.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETN98536.1 - 1.2e-05 25.1 0.3 0.015 15.2 0.0 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.10 ETN98536.1 - 7.7e-05 22.3 0.2 0.038 13.7 0.0 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 ETN98536.1 - 0.0039 17.3 0.0 2.6 8.3 0.0 2.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Nup160 PF11715.3 ETN98536.1 - 0.025 12.7 0.0 0.037 12.1 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 WD40 PF00400.27 ETN98537.1 - 1.1e-13 50.5 4.2 5.7e-11 41.8 0.8 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat zf-TRAF PF02176.13 ETN98537.1 - 4.7e-06 26.8 6.5 2.3e-05 24.6 4.5 2.3 1 0 0 1 1 1 1 TRAF-type zinc finger Nup160 PF11715.3 ETN98537.1 - 0.00011 20.5 0.7 0.00011 20.5 0.5 1.7 2 0 0 2 2 2 1 Nucleoporin Nup120/160 APG6 PF04111.7 ETN98537.1 - 0.035 13.1 23.6 0.058 12.4 16.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 zf-C3HC4_2 PF13923.1 ETN98537.1 - 0.35 10.9 15.5 0.054 13.5 2.9 3.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) OTCace PF00185.19 ETN98537.1 - 0.46 10.3 0.0 0.46 10.3 0.0 2.5 2 1 0 2 2 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF641 PF04859.7 ETN98537.1 - 1.3 8.7 23.6 4.8 6.9 6.4 2.6 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Vfa1 PF08432.5 ETN98537.1 - 1.3 8.9 35.0 0.086 12.8 16.6 2.8 2 1 1 3 3 3 0 AAA-ATPase Vps4-associated protein 1 TMF_TATA_bd PF12325.3 ETN98537.1 - 2.9 7.6 28.8 17 5.1 19.2 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF342 PF03961.8 ETN98537.1 - 7.9 4.7 23.9 13 4.0 16.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF972 PF06156.8 ETN98537.1 - 9.5 6.6 29.1 0.25 11.7 4.8 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) ABC2_membrane_3 PF12698.2 ETN98539.1 - 0.011 14.7 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF3592 PF12158.3 ETN98539.1 - 0.017 14.9 0.1 0.026 14.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) Choline_transpo PF04515.7 ETN98539.1 - 0.019 13.6 0.0 0.031 13.0 0.0 1.3 1 0 0 1 1 1 0 Plasma-membrane choline transporter DUF3278 PF11683.3 ETN98539.1 - 0.023 14.6 0.1 5.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) TMEM154 PF15102.1 ETN98539.1 - 0.054 13.2 0.4 0.098 12.3 0.2 1.5 1 1 0 1 1 1 0 TMEM154 protein family AA_permease_2 PF13520.1 ETN98539.1 - 0.12 10.8 0.8 0.16 10.4 0.5 1.1 1 0 0 1 1 1 0 Amino acid permease FlxA PF14282.1 ETN98540.1 - 0.003 17.4 32.4 0.011 15.6 6.1 3.1 2 1 1 3 3 3 1 FlxA-like protein Tropomyosin_1 PF12718.2 ETN98540.1 - 0.003 17.4 28.8 0.0063 16.3 4.4 3.1 1 1 2 3 3 3 1 Tropomyosin like DUF4200 PF13863.1 ETN98540.1 - 0.0034 17.3 5.6 0.0034 17.3 3.9 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4200) Reo_sigmaC PF04582.7 ETN98540.1 - 0.0053 15.9 1.5 0.0053 15.9 1.1 2.0 1 1 1 2 2 2 1 Reovirus sigma C capsid protein THOC7 PF05615.8 ETN98540.1 - 0.019 15.2 7.3 0.019 15.2 5.1 2.5 1 1 1 2 2 2 0 Tho complex subunit 7 Baculo_PEP_C PF04513.7 ETN98540.1 - 0.026 14.3 9.8 0.049 13.4 3.3 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.1 ETN98540.1 - 0.029 12.8 19.2 0.039 12.4 13.3 1.2 1 0 0 1 1 1 0 AAA domain PspA_IM30 PF04012.7 ETN98540.1 - 0.035 13.4 23.4 0.022 14.1 4.1 2.7 2 1 0 2 2 2 0 PspA/IM30 family Sas10 PF09368.5 ETN98540.1 - 0.079 13.1 0.2 0.079 13.1 0.2 2.1 3 0 0 3 3 1 0 Sas10 C-terminal domain Laminin_II PF06009.7 ETN98540.1 - 0.08 12.7 17.1 0.066 12.9 3.3 3.1 1 1 2 3 3 3 0 Laminin Domain II TMF_DNA_bd PF12329.3 ETN98540.1 - 0.12 12.1 29.9 0.037 13.8 3.0 4.3 3 1 1 4 4 3 0 TATA element modulatory factor 1 DNA binding Tektin PF03148.9 ETN98540.1 - 0.14 10.7 20.5 0.18 10.3 12.3 2.2 1 1 1 2 2 2 0 Tektin family HrpB7 PF09486.5 ETN98540.1 - 0.15 12.0 11.4 0.7 9.8 7.7 2.3 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF3138 PF11336.3 ETN98540.1 - 0.16 10.1 2.7 0.24 9.5 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Phage_pRha PF09669.5 ETN98540.1 - 0.24 11.7 7.2 0.33 11.3 0.5 2.3 2 0 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) MtrB PF05440.7 ETN98540.1 - 0.26 11.3 3.3 5.2 7.1 0.1 2.8 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B LPP PF04728.8 ETN98540.1 - 0.26 11.0 5.1 3.5 7.4 0.3 3.1 2 1 1 3 3 3 0 Lipoprotein leucine-zipper Osmo_CC PF08946.5 ETN98540.1 - 0.27 11.2 16.1 1.8 8.6 0.0 4.4 4 1 1 5 5 4 0 Osmosensory transporter coiled coil HR1 PF02185.11 ETN98540.1 - 0.3 10.8 28.5 0.46 10.2 0.4 4.6 2 2 3 5 5 5 0 Hr1 repeat CortBP2 PF09727.4 ETN98540.1 - 0.31 10.5 19.8 1.2 8.6 1.0 2.2 2 0 0 2 2 2 0 Cortactin-binding protein-2 Spc7 PF08317.6 ETN98540.1 - 0.88 8.1 24.6 0.55 8.8 5.0 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF2431 PF10354.4 ETN98540.1 - 1.1 9.1 6.3 0.4 10.6 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2431) End3 PF12761.2 ETN98540.1 - 1.6 8.3 18.4 0.59 9.7 10.7 1.8 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Ndc1_Nup PF09531.5 ETN98540.1 - 1.8 6.8 7.1 2.1 6.6 4.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Otopetrin PF03189.8 ETN98540.1 - 2.3 7.1 5.2 3 6.7 3.6 1.2 1 0 0 1 1 1 0 Otopetrin Snapin_Pallidin PF14712.1 ETN98540.1 - 2.4 8.5 18.8 0.1 12.8 4.4 2.5 2 1 0 2 2 2 0 Snapin/Pallidin DUF4407 PF14362.1 ETN98540.1 - 2.7 6.8 21.9 6.8 5.5 15.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Nup54 PF13874.1 ETN98540.1 - 2.8 7.6 19.7 0.47 10.1 9.0 2.5 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 RyR PF02026.11 ETN98540.1 - 2.8 8.0 7.1 2.4 8.2 2.2 2.6 2 2 1 3 3 3 0 RyR domain MerR-DNA-bind PF09278.6 ETN98540.1 - 3.3 8.1 19.1 16 5.9 0.1 4.7 3 2 2 5 5 5 0 MerR, DNA binding APG6 PF04111.7 ETN98540.1 - 4 6.3 28.4 1.1 8.1 11.7 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF3450 PF11932.3 ETN98540.1 - 5.1 6.2 25.1 0.058 12.6 5.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) NPV_P10 PF05531.7 ETN98540.1 - 7.9 6.8 15.4 5.2 7.3 2.4 3.4 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.6 ETN98540.1 - 9.3 6.2 15.8 0.56 10.1 1.2 3.9 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) NARP1 PF12569.3 ETN98543.1 - 0.47 9.1 10.7 0.31 9.7 6.1 1.5 1 1 0 2 2 2 0 NMDA receptor-regulated protein 1 RNA_pol_Rpc4 PF05132.9 ETN98543.1 - 1.9 8.4 10.9 6.7 6.7 4.7 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 Ca_hom_mod PF14798.1 ETN98544.1 - 0.00025 20.1 0.0 0.00031 19.7 0.0 1.2 1 0 0 1 1 1 1 Calcium homeostasis modulator FA_desaturase PF00487.19 ETN98545.1 - 6.3e-13 48.7 8.1 8.2e-13 48.3 5.6 1.1 1 0 0 1 1 1 1 Fatty acid desaturase CAF-1_p150 PF11600.3 ETN98546.1 - 0.033 13.5 21.0 0.049 12.9 14.6 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FNIP_N PF14636.1 ETN98546.1 - 0.038 14.4 3.0 0.081 13.3 2.1 1.5 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus ATP1G1_PLM_MAT8 PF02038.11 ETN98546.1 - 1.4 8.0 4.5 0.33 10.0 0.1 2.1 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family P5-ATPase PF12409.3 ETN98546.1 - 1.9 8.3 5.5 0.75 9.6 0.1 2.2 1 1 1 2 2 2 0 P5-type ATPase cation transporter NDUF_B5 PF09781.4 ETN98546.1 - 6.3 6.0 9.1 11 5.2 6.3 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit CDC73 PF05179.9 ETN98547.1 - 1.3e-41 142.7 3.3 1.3e-41 142.7 2.3 2.0 2 0 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family TPR_12 PF13424.1 ETN98548.1 - 1.5e-31 108.1 0.1 1.8e-16 59.8 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETN98548.1 - 4.5e-28 96.7 12.6 1.2e-13 50.4 0.3 3.2 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETN98548.1 - 6.9e-21 72.9 11.5 2e-08 33.4 0.3 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETN98548.1 - 4.8e-20 69.8 6.6 1.7e-07 30.5 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETN98548.1 - 1.4e-17 62.0 0.1 2.2e-05 23.9 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETN98548.1 - 3.1e-15 54.7 9.8 6.7e-06 25.5 0.2 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETN98548.1 - 4.3e-13 48.7 0.0 0.00029 20.6 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETN98548.1 - 6e-07 29.9 0.0 0.0098 16.5 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETN98548.1 - 1.5e-06 28.3 0.0 1.4 9.7 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETN98548.1 - 2.5e-06 27.5 2.3 0.02 15.3 0.1 4.3 5 0 0 5 5 4 1 Tetratricopeptide repeat SNAP PF14938.1 ETN98548.1 - 0.00025 20.2 0.6 0.018 14.2 0.1 2.3 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP Apc3 PF12895.2 ETN98548.1 - 0.00063 19.8 2.7 0.0031 17.6 1.1 2.7 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 ETN98548.1 - 0.0033 17.5 0.6 1.8 8.9 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_3 PF07720.7 ETN98548.1 - 0.013 15.2 1.7 0.013 15.2 1.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETN98548.1 - 0.037 14.3 0.1 2.4 8.5 0.0 2.8 2 1 1 3 3 2 0 Tetratricopeptide repeat Sel1 PF08238.7 ETN98548.1 - 0.047 14.3 5.0 5.4 7.7 0.0 3.4 3 0 0 3 3 3 0 Sel1 repeat MIT PF04212.13 ETN98548.1 - 0.055 13.3 6.4 0.76 9.7 0.0 3.9 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain GLTSCR1 PF15249.1 ETN98548.1 - 0.085 12.9 0.1 0.26 11.3 0.1 1.8 1 0 0 1 1 1 0 Glioma tumor suppressor candidate region GP11 PF08677.5 ETN98549.1 - 0.041 13.0 0.1 0.093 11.8 0.0 1.5 1 0 0 1 1 1 0 GP11 baseplate wedge protein BCL_N PF04714.8 ETN98549.1 - 0.099 12.2 0.3 0.23 11.0 0.2 1.5 1 0 0 1 1 1 0 BCL7, N-terminal conserver region AAA PF00004.24 ETN98551.1 - 3e-07 30.6 0.0 0.00016 21.8 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETN98551.1 - 2.2e-05 24.6 0.0 0.036 14.1 0.0 3.8 3 0 0 3 3 3 1 AAA domain DUF815 PF05673.8 ETN98551.1 - 0.00084 18.3 0.0 0.0019 17.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 ETN98551.1 - 0.0026 18.0 0.1 0.018 15.3 0.0 2.5 2 0 0 2 2 2 1 ABC transporter DUF258 PF03193.11 ETN98551.1 - 0.0032 16.6 0.0 0.0098 15.0 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_5 PF07728.9 ETN98551.1 - 0.0043 16.7 0.0 0.058 13.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NACHT PF05729.7 ETN98551.1 - 0.0045 16.6 0.8 2.2 7.9 0.1 3.9 3 0 0 3 3 3 1 NACHT domain Sigma54_activ_2 PF14532.1 ETN98551.1 - 0.034 14.2 0.1 0.34 10.9 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 ETN98551.1 - 0.034 13.5 0.3 0.9 8.9 0.0 3.1 3 1 1 4 4 4 0 IstB-like ATP binding protein AAA_16 PF13191.1 ETN98551.1 - 0.099 12.6 0.0 0.78 9.6 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain WD40 PF00400.27 ETN98553.1 - 1.1e-46 155.0 17.2 1.3e-10 40.6 0.2 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETN98553.1 - 5.6e-11 41.2 3.7 0.0013 16.9 0.0 4.8 2 1 3 5 5 5 4 Nucleoporin Nup120/160 DUF851 PF05867.6 ETN98553.1 - 0.0012 18.1 0.0 0.55 9.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF851) BBS2_Mid PF14783.1 ETN98553.1 - 0.0012 18.5 2.8 0.97 9.2 0.2 3.3 3 2 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region zf-C2H2_6 PF13912.1 ETN98553.1 - 0.088 12.7 1.8 5.9 6.9 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger UBN_AB PF14075.1 ETN98555.1 - 0.026 14.2 2.0 0.046 13.3 1.1 1.6 1 1 1 2 2 2 0 Ubinuclein conserved middle domain PRP1_N PF06424.7 ETN98555.1 - 0.036 14.3 0.6 0.062 13.6 0.4 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal MlrC_C PF07171.7 ETN98555.1 - 0.083 12.4 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 MlrC C-terminus Tup_N PF08581.5 ETN98556.1 - 0.33 11.1 8.1 2.1 8.5 2.1 2.5 2 0 0 2 2 2 0 Tup N-terminal TSC22 PF01166.13 ETN98556.1 - 1.4 8.9 5.5 1 9.3 0.5 3.0 3 0 0 3 3 3 0 TSC-22/dip/bun family DUF972 PF06156.8 ETN98556.1 - 3.1 8.1 9.7 0.47 10.8 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF972) PUB PF09409.5 ETN98557.1 - 0.00072 19.2 1.8 0.006 16.3 1.2 2.4 1 1 0 1 1 1 1 PUB domain DUF2951 PF11166.3 ETN98557.1 - 0.69 9.8 6.0 0.3 10.9 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) WD40 PF00400.27 ETN98559.1 - 1.2e-14 53.5 8.0 8.2e-10 38.1 0.3 3.2 3 1 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETN98559.1 - 0.04 12.0 0.1 0.56 8.2 0.1 2.0 1 1 0 1 1 1 0 Nucleoporin Nup120/160 RTC_insert PF05189.8 ETN98560.1 - 0.013 15.4 0.1 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase (RTC), insert domain Menin PF05053.8 ETN98560.1 - 1.7 6.6 14.0 1.5 6.9 9.2 1.3 1 1 0 1 1 1 0 Menin FAM176 PF14851.1 ETN98561.1 - 1.3e-06 28.1 0.1 0.00018 21.2 0.0 2.2 2 0 0 2 2 2 2 FAM176 family DUF4611 PF15387.1 ETN98561.1 - 0.037 14.1 0.8 0.037 14.1 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF1510 PF07423.6 ETN98561.1 - 0.78 9.0 5.1 14 4.9 2.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1510) RXT2_N PF08595.6 ETN98561.1 - 2.2 8.0 5.8 4.3 7.1 0.9 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF4363 PF14276.1 ETN98562.1 - 0.013 15.2 0.3 0.029 14.0 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4363) PI3Ka PF00613.15 ETN98562.1 - 0.11 11.7 0.3 0.13 11.4 0.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF1900 PF08954.6 ETN98563.1 - 0.0091 15.5 0.4 0.055 13.0 0.3 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1900) PPR_2 PF13041.1 ETN98563.1 - 0.015 15.2 0.8 0.037 13.9 0.1 1.9 2 0 0 2 2 2 0 PPR repeat family Pentapeptide PF00805.17 ETN98564.1 - 1.5e-07 30.4 2.7 0.00069 18.7 0.2 2.0 1 1 1 2 2 2 2 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 ETN98564.1 - 1.9e-05 24.4 0.1 3.9e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.1 ETN98564.1 - 2.4e-05 24.0 2.2 2.6e-05 23.9 0.6 1.7 1 1 1 2 2 2 1 Pentapeptide repeats (9 copies) WD40 PF00400.27 ETN98564.1 - 0.0014 18.4 0.0 0.0031 17.3 0.0 1.6 1 0 0 1 1 1 1 WD domain, G-beta repeat SHMT PF00464.14 ETN98564.1 - 0.067 11.5 0.1 0.098 10.9 0.1 1.2 1 0 0 1 1 1 0 Serine hydroxymethyltransferase Bud13 PF09736.4 ETN98566.1 - 0.22 11.7 6.2 0.2 11.8 3.3 1.6 1 1 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex CorA PF01544.13 ETN98567.1 - 1.4e-14 53.8 0.5 1.5e-14 53.7 0.4 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein zf-LITAF-like PF10601.4 ETN98567.1 - 0.11 12.3 4.8 0.15 11.9 0.4 2.1 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain GreA_GreB_N PF03449.10 ETN98570.1 - 0.014 15.4 0.3 0.023 14.7 0.2 1.5 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal Cluap1 PF10234.4 ETN98571.1 - 0.045 12.9 2.1 0.057 12.6 1.4 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF2070 PF09843.4 ETN98571.1 - 0.059 12.8 0.0 0.077 12.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Cas_Csx8 PF09657.5 ETN98571.1 - 0.065 11.9 3.6 0.075 11.7 2.5 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Csx8 (Cas_Csx8) SH3BP5 PF05276.9 ETN98571.1 - 0.19 11.0 2.6 0.27 10.4 1.8 1.3 1 1 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) Cep57_MT_bd PF06657.8 ETN98571.1 - 0.44 10.5 4.3 10 6.1 0.1 2.3 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Ldl_recept_a PF00057.13 ETN98572.1 - 0.0024 17.7 2.3 0.0052 16.6 1.6 1.5 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Ribosomal_L14e PF01929.12 ETN98572.1 - 0.092 13.1 1.3 0.14 12.5 0.2 1.8 2 0 0 2 2 2 0 Ribosomal protein L14 ABC2_membrane_5 PF13346.1 ETN98573.1 - 0.027 13.7 11.8 0.033 13.4 8.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2547 PF10818.3 ETN98573.1 - 0.56 10.8 3.5 0.35 11.5 1.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) DUF2207 PF09972.4 ETN98573.1 - 3 6.3 11.7 5 5.5 8.1 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) PDR_CDR PF06422.7 ETN98573.1 - 5.7 6.6 12.5 0.88 9.2 1.8 2.3 1 1 1 2 2 2 0 CDR ABC transporter SRP19 PF01922.12 ETN98574.1 - 0.086 13.4 0.3 0.3 11.7 0.0 1.9 2 0 0 2 2 2 0 SRP19 protein TPR_12 PF13424.1 ETN98578.1 - 7.5e-51 169.9 7.0 8e-24 83.3 0.2 2.9 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETN98578.1 - 3e-34 115.9 3.0 3.1e-10 39.6 0.0 4.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETN98578.1 - 6.8e-29 98.2 18.9 7.5e-10 38.0 0.5 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETN98578.1 - 1.8e-27 94.7 4.3 1.1e-17 63.4 0.3 2.1 2 0 0 2 2 2 2 TPR repeat TPR_7 PF13176.1 ETN98578.1 - 6.4e-26 88.0 0.5 2.1e-07 30.2 0.0 3.4 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETN98578.1 - 1.2e-24 84.2 20.6 2e-08 33.4 0.7 3.5 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETN98578.1 - 4.4e-24 82.4 9.3 2.5e-07 30.1 0.2 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETN98578.1 - 1.6e-12 46.5 8.5 0.0055 16.8 0.1 4.9 4 3 0 4 4 4 3 Tetratricopeptide repeat TPR_3 PF07720.7 ETN98578.1 - 6e-11 41.8 6.5 0.0027 17.4 0.1 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETN98578.1 - 2.7e-10 40.0 0.1 0.12 12.8 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETN98578.1 - 1.4e-09 38.3 0.0 0.00032 21.2 0.0 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETN98578.1 - 1.8e-09 37.3 0.0 0.32 11.7 0.0 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat Apc3 PF12895.2 ETN98578.1 - 2.7e-09 37.0 5.9 0.00014 21.9 1.1 3.0 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 ETN98578.1 - 5.4e-07 29.3 7.8 0.0041 16.9 0.2 3.1 3 0 0 3 3 3 3 MIT (microtubule interacting and transport) domain Sel1 PF08238.7 ETN98578.1 - 6.4e-07 29.8 7.1 0.098 13.3 0.0 3.5 3 0 0 3 3 3 3 Sel1 repeat ATP-synt_E_2 PF08112.6 ETN98578.1 - 8.6e-06 25.7 3.8 0.51 10.4 0.1 3.2 3 0 0 3 3 3 2 ATP synthase epsilon subunit TPR_19 PF14559.1 ETN98578.1 - 1.8e-05 24.9 0.2 0.0099 16.2 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETN98578.1 - 2.2e-05 23.5 0.0 1.6 8.0 0.0 3.3 3 0 0 3 3 3 2 SHNi-TPR PPR PF01535.15 ETN98578.1 - 5.3e-05 22.9 2.5 0.099 12.6 0.1 3.3 3 0 0 3 3 3 1 PPR repeat Mob_Pre PF01076.14 ETN98578.1 - 0.00027 20.6 0.1 0.00078 19.1 0.0 1.6 1 1 0 1 1 1 1 Plasmid recombination enzyme DUF2642 PF10842.3 ETN98578.1 - 0.00028 20.3 0.0 12 5.4 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2642) RPN7 PF10602.4 ETN98578.1 - 0.00034 20.0 3.6 0.12 11.6 0.3 2.8 1 1 0 2 2 2 2 26S proteasome subunit RPN7 SNAP PF14938.1 ETN98578.1 - 0.00074 18.7 3.8 0.21 10.6 0.5 2.2 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP DUF627 PF04781.7 ETN98578.1 - 0.00099 18.7 0.3 3.9 7.1 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF627) PPR_2 PF13041.1 ETN98578.1 - 0.0041 17.0 1.3 0.97 9.4 0.0 3.1 3 0 0 3 3 3 1 PPR repeat family DUF1498 PF07385.7 ETN98578.1 - 0.0044 16.1 0.2 2.7 7.1 0.0 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF1498) EST1_DNA_bind PF10373.4 ETN98578.1 - 0.0063 15.7 1.9 5.1 6.2 0.0 3.0 3 0 0 3 3 3 0 Est1 DNA/RNA binding domain Pep3_Vps18 PF05131.9 ETN98578.1 - 0.027 13.9 0.1 9.7 5.6 0.0 3.0 3 0 0 3 3 3 0 Pep3/Vps18/deep orange family YlbE PF14003.1 ETN98578.1 - 0.037 14.0 0.0 22 5.2 0.0 3.1 3 0 0 3 3 3 0 YlbE-like protein TPR_5 PF12688.2 ETN98578.1 - 0.04 13.9 0.1 7.3 6.6 0.0 2.9 2 1 1 3 3 3 0 Tetratrico peptide repeat Ten1_2 PF15490.1 ETN98578.1 - 0.041 13.4 0.0 6.5 6.3 0.0 2.9 1 1 2 3 3 3 0 Telomere-capping, CST complex subunit mRNA_cap_C PF03919.10 ETN98578.1 - 0.051 13.8 0.0 21 5.5 0.0 2.8 3 0 0 3 3 3 0 mRNA capping enzyme, C-terminal domain DBD_Tnp_Mut PF03108.10 ETN98578.1 - 0.074 12.6 0.0 32 4.1 0.0 3.0 3 0 0 3 3 3 0 MuDR family transposase TCTP PF00838.12 ETN98578.1 - 0.12 12.3 1.5 10 6.1 0.0 2.8 1 1 2 3 3 3 0 Translationally controlled tumour protein Musclin PF11037.3 ETN98578.1 - 0.13 11.8 0.0 13 5.3 0.0 2.8 2 1 1 3 3 3 0 Insulin-resistance promoting peptide in skeletal muscle Y1_Tnp PF01797.11 ETN98578.1 - 0.18 11.6 4.8 11 5.8 0.1 3.5 1 1 3 4 4 4 0 Transposase IS200 like Fis1_TPR_C PF14853.1 ETN98578.1 - 0.24 11.2 6.8 3.9 7.4 0.1 3.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Vps39_1 PF10366.4 ETN98578.1 - 0.26 11.3 1.9 2.9 7.9 0.1 2.7 1 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 1 Ubiq-assoc PF09145.5 ETN98578.1 - 6.9 6.6 12.4 28 4.6 0.1 4.4 3 2 1 4 4 4 0 Ubiquitin-associated AAA_5 PF07728.9 ETN98579.1 - 1.5e-07 31.2 0.0 3.2e-07 30.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 ETN98579.1 - 2.1e-06 27.9 0.0 4.9e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 ETN98579.1 - 6.4e-05 23.2 0.0 0.00017 21.9 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_14 PF13173.1 ETN98579.1 - 0.00061 19.6 0.1 0.0023 17.8 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETN98579.1 - 0.00079 19.5 0.0 0.0043 17.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 ETN98579.1 - 0.00088 18.4 0.0 0.0015 17.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 ETN98579.1 - 0.0021 18.0 0.0 0.0034 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.4 ETN98579.1 - 0.0026 17.2 0.0 0.0053 16.2 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Sigma54_activ_2 PF14532.1 ETN98579.1 - 0.0041 17.1 0.0 0.012 15.6 0.0 1.8 2 0 0 2 2 2 1 Sigma-54 interaction domain Miro PF08477.8 ETN98579.1 - 0.0049 17.3 0.1 0.016 15.7 0.1 1.9 1 1 0 1 1 1 1 Miro-like protein UPF0079 PF02367.12 ETN98579.1 - 0.0075 15.9 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 DUF815 PF05673.8 ETN98579.1 - 0.0082 15.1 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_15 PF13175.1 ETN98579.1 - 0.015 14.4 0.9 0.082 11.9 0.0 2.2 3 0 0 3 3 3 0 AAA ATPase domain Rad17 PF03215.10 ETN98579.1 - 0.016 13.9 0.4 0.28 9.8 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein MCM PF00493.18 ETN98579.1 - 0.016 14.0 0.0 0.035 12.9 0.0 1.5 1 0 0 1 1 1 0 MCM2/3/5 family Arch_ATPase PF01637.13 ETN98579.1 - 0.017 14.8 0.1 0.086 12.5 0.0 2.2 3 0 0 3 3 3 0 Archaeal ATPase AAA_24 PF13479.1 ETN98579.1 - 0.022 14.3 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 ETN98579.1 - 0.023 14.3 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 ETN98579.1 - 0.025 14.2 0.4 0.12 12.0 0.1 2.2 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 ETN98579.1 - 0.027 13.9 0.1 0.078 12.4 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_17 PF13207.1 ETN98579.1 - 0.07 13.9 0.0 0.31 11.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.1 ETN98579.1 - 0.083 12.8 0.4 0.38 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 ETN98579.1 - 0.098 12.8 0.0 0.32 11.1 0.0 2.0 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.18 ETN98579.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.13 ETN98579.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Bac_DnaA PF00308.13 ETN98579.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_23 PF13476.1 ETN98579.1 - 0.21 11.9 2.8 0.32 11.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain WD40 PF00400.27 ETN98580.1 - 4.8e-17 61.1 7.0 4.3e-10 39.0 0.2 4.3 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN98580.1 - 0.0042 15.2 1.1 0.91 7.5 0.0 2.8 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETN98580.1 - 0.0061 15.3 1.5 0.0094 14.7 1.0 1.4 1 1 0 1 1 1 1 Nup133 N terminal like Apis_Csd PF11671.3 ETN98581.1 - 0.4 10.4 8.4 0.54 10.0 5.8 1.2 1 0 0 1 1 1 0 Complementary sex determiner protein Strabismus PF06638.6 ETN98581.1 - 0.48 8.6 3.1 0.52 8.5 2.1 1.0 1 0 0 1 1 1 0 Strabismus protein OSTbeta PF15048.1 ETN98581.1 - 0.88 9.6 4.4 0.94 9.5 3.1 1.2 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Fascin PF06268.8 ETN98584.1 - 0.0066 16.5 0.1 0.01 15.9 0.1 1.2 1 0 0 1 1 1 1 Fascin domain OEP PF02321.13 ETN98584.1 - 0.087 12.4 3.2 0.13 11.8 2.2 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein Lipocalin_3 PF12702.2 ETN98584.1 - 0.088 12.8 0.8 0.17 11.9 0.5 1.7 1 1 0 1 1 1 0 Lipocalin-like DUF947 PF06102.7 ETN98584.1 - 3.3 7.5 9.8 5 6.9 6.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF947) P21-Arc PF04062.9 ETN98585.1 - 0.58 9.9 3.4 1.5 8.5 2.4 1.7 1 1 0 1 1 1 0 ARP2/3 complex ARPC3 (21 kDa) subunit RNA_pol_Rpb2_6 PF00562.23 ETN98586.1 - 0.36 9.5 4.8 0.37 9.4 3.3 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 DUF2325 PF10087.4 ETN98586.1 - 0.37 10.6 3.7 0.6 9.9 2.6 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) WD40 PF00400.27 ETN98587.1 - 2.3e-43 144.5 7.5 1.8e-14 52.9 0.0 4.0 4 0 0 4 4 4 4 WD domain, G-beta repeat eIF2A PF08662.6 ETN98587.1 - 5.2e-08 32.8 0.1 8e-08 32.2 0.1 1.3 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETN98587.1 - 4.3e-07 28.4 2.8 0.00015 20.0 0.1 2.6 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETN98587.1 - 7.3e-05 21.2 0.1 0.00028 19.3 0.1 1.8 1 1 0 1 1 1 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETN98587.1 - 0.00092 18.0 2.5 0.11 11.2 0.2 2.8 1 1 2 3 3 3 2 Nup133 N terminal like PQQ_2 PF13360.1 ETN98587.1 - 0.0013 18.2 0.2 0.0043 16.5 0.1 1.6 1 1 0 1 1 1 1 PQQ-like domain DPPIV_N PF00930.16 ETN98587.1 - 0.0061 15.1 0.0 0.12 10.9 0.0 2.3 1 1 1 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.7 ETN98587.1 - 0.012 15.2 4.5 1.7 8.4 0.2 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 ETN98587.1 - 0.015 14.3 0.3 0.69 8.9 0.0 2.5 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal SGL PF08450.7 ETN98587.1 - 0.02 14.3 0.3 0.033 13.5 0.2 1.4 1 1 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region B_lectin PF01453.19 ETN98587.1 - 0.035 13.9 1.5 0.088 12.7 1.0 1.6 1 1 1 2 2 2 0 D-mannose binding lectin Gmad1 PF10647.4 ETN98587.1 - 0.042 13.2 0.0 0.16 11.3 0.0 1.7 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain Hira PF07569.6 ETN98587.1 - 0.045 12.9 0.1 5.3 6.1 0.0 2.3 1 1 1 2 2 2 0 TUP1-like enhancer of split Ricin_B_lectin PF00652.17 ETN98587.1 - 0.046 13.7 0.8 0.073 13.1 0.5 1.4 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain WD40 PF00400.27 ETN98589.1 - 3.3e-20 71.1 6.3 2.8e-10 39.6 0.5 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETN98589.1 - 4.6e-07 28.3 3.1 7.3e-05 21.0 0.3 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PspB PF06667.7 ETN98589.1 - 0.024 14.5 1.3 0.96 9.4 0.1 2.8 3 0 0 3 3 3 0 Phage shock protein B Zn-ribbon_8 PF09723.5 ETN98591.1 - 0.006 16.5 0.5 0.015 15.2 0.0 1.9 2 0 0 2 2 2 1 Zinc ribbon domain DUF3080 PF11279.3 ETN98591.1 - 0.32 10.1 6.1 0.04 13.0 1.6 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3080) BRCT PF00533.21 ETN98591.1 - 0.44 10.7 3.9 0.29 11.3 0.2 2.6 2 1 1 3 3 3 0 BRCA1 C Terminus (BRCT) domain DUF4094 PF13334.1 ETN98591.1 - 5.9 7.3 8.2 2.1 8.7 2.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Peptidase_C23 PF05379.6 ETN98592.1 - 0.02 14.8 0.1 0.038 13.9 0.1 1.4 1 0 0 1 1 1 0 Carlavirus endopeptidase Solute_trans_a PF03619.11 ETN98593.1 - 2.9e-38 131.7 7.0 3.9e-38 131.3 4.8 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha MotCF PF09158.5 ETN98594.1 - 0.00047 19.7 0.3 0.00066 19.3 0.2 1.3 1 0 0 1 1 1 1 Bacteriophage T4 MotA, C-terminal CRAL_TRIO PF00650.15 ETN98596.1 - 8.7e-12 44.8 0.2 1.1e-11 44.5 0.1 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain Baculo_PEP_C PF04513.7 ETN98597.1 - 3 7.6 11.6 2.4 7.9 2.0 2.9 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CRF PF00473.12 ETN98597.1 - 3.1 7.9 6.8 11 6.2 0.5 2.9 2 0 0 2 2 2 0 Corticotropin-releasing factor family Spc7 PF08317.6 ETN98597.1 - 5.7 5.5 47.2 0.075 11.6 11.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4239 PF14023.1 ETN98597.1 - 7.3 5.8 13.4 1.8 7.8 3.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4239) Acyl-CoA_ox_N PF14749.1 ETN98598.1 - 0.07 13.4 2.7 0.054 13.7 0.6 1.7 1 1 1 2 2 2 0 Acyl-coenzyme A oxidase N-terminal YMF19 PF02326.10 ETN98598.1 - 0.17 12.5 4.2 0.5 10.9 2.7 2.1 1 1 0 1 1 1 0 Plant ATP synthase F0 SurA_N_2 PF13623.1 ETN98598.1 - 0.27 11.2 2.9 0.94 9.4 1.7 1.9 1 1 1 2 2 2 0 SurA N-terminal domain Ndc1_Nup PF09531.5 ETN98598.1 - 2.4 6.4 6.3 3.1 6.1 4.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Bap31 PF05529.7 ETN98598.1 - 7.7 5.9 7.9 26 4.1 5.5 1.9 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like Kelch_1 PF01344.20 ETN98600.1 - 9.1e-10 37.9 4.1 4.3e-06 26.1 0.4 3.0 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETN98600.1 - 1.5e-06 28.1 7.9 0.00049 20.1 0.4 3.4 3 1 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETN98600.1 - 5.8e-05 22.7 3.0 0.00044 19.9 0.1 2.7 3 1 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETN98600.1 - 0.0013 18.6 7.4 0.044 13.7 0.5 2.8 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 ETN98600.1 - 0.025 14.3 0.7 3.7 7.4 0.0 3.1 3 0 0 3 3 3 0 Kelch motif Kelch_3 PF13415.1 ETN98600.1 - 0.07 13.3 0.5 2 8.6 0.0 2.6 2 0 0 2 2 2 0 Galactose oxidase, central domain IncA PF04156.9 ETN98601.1 - 0.00072 19.1 25.6 0.00072 19.1 17.8 3.0 1 1 2 3 3 3 1 IncA protein CENP-F_leu_zip PF10473.4 ETN98601.1 - 0.0028 17.5 66.3 0.047 13.5 9.1 3.5 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF641 PF04859.7 ETN98601.1 - 0.01 15.5 9.6 0.01 15.5 6.7 4.1 1 1 3 4 4 4 0 Plant protein of unknown function (DUF641) BLOC1_2 PF10046.4 ETN98601.1 - 0.023 14.8 12.8 0.023 14.8 8.8 5.0 1 1 4 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GAS PF13851.1 ETN98601.1 - 0.023 13.8 73.5 0.045 12.9 17.2 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.2 ETN98601.1 - 0.03 14.1 68.9 1.1 9.1 23.2 3.1 1 1 2 3 3 3 0 Tropomyosin like Reo_sigmaC PF04582.7 ETN98601.1 - 0.042 13.0 11.4 0.12 11.5 2.8 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF3584 PF12128.3 ETN98601.1 - 0.15 9.3 55.3 0.35 8.1 23.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Filament PF00038.16 ETN98601.1 - 0.17 11.3 56.6 0.41 10.0 14.4 3.1 1 1 2 3 3 3 0 Intermediate filament protein ERM PF00769.14 ETN98601.1 - 0.17 11.3 61.1 0.031 13.8 34.0 2.9 1 1 1 2 2 2 0 Ezrin/radixin/moesin family ATG16 PF08614.6 ETN98601.1 - 0.21 11.3 63.3 0.026 14.3 16.6 3.5 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Tropomyosin PF00261.15 ETN98601.1 - 0.46 9.5 61.5 0.29 10.1 10.5 2.9 1 1 1 2 2 2 0 Tropomyosin Myosin_tail_1 PF01576.14 ETN98601.1 - 0.73 7.4 61.2 1.4 6.4 42.4 1.4 1 1 0 1 1 1 0 Myosin tail TPR_MLP1_2 PF07926.7 ETN98601.1 - 0.76 9.5 69.7 0.52 10.0 18.7 3.7 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein TBPIP PF07106.8 ETN98601.1 - 0.87 9.1 64.9 1.3 8.5 16.0 3.1 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) BicD PF09730.4 ETN98601.1 - 1.9 6.7 53.8 0.25 9.6 24.2 2.1 1 1 1 2 2 2 0 Microtubule-associated protein Bicaudal-D Fib_alpha PF08702.5 ETN98601.1 - 2.8 8.0 51.6 4.2 7.4 15.5 3.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Atg14 PF10186.4 ETN98601.1 - 3.5 6.4 58.3 0.022 13.6 14.9 3.0 1 1 2 3 3 2 0 UV radiation resistance protein and autophagy-related subunit 14 Mod_r PF07200.8 ETN98601.1 - 3.9 7.3 58.1 2.4 8.0 10.7 4.1 1 1 3 4 4 4 0 Modifier of rudimentary (Mod(r)) protein bZIP_1 PF00170.16 ETN98601.1 - 4.1 7.4 61.7 0.13 12.2 1.7 6.9 3 2 4 7 7 6 0 bZIP transcription factor Spectrin PF00435.16 ETN98601.1 - 4.7 7.5 48.0 0.44 10.8 6.7 4.1 1 1 3 4 4 4 0 Spectrin repeat DUF869 PF05911.6 ETN98601.1 - 5.2 5.1 57.2 0.4 8.8 27.7 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) APG6 PF04111.7 ETN98601.1 - 6.2 5.7 67.0 0.16 11.0 19.7 3.1 1 1 2 3 3 3 0 Autophagy protein Apg6 Mnd1 PF03962.10 ETN98601.1 - 8.2 6.0 61.6 4.8 6.8 7.3 3.1 1 1 2 3 3 3 0 Mnd1 family SecA_DEAD PF07517.9 ETN98602.1 - 1.5e-06 27.6 0.0 3.1e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 SecA DEAD-like domain DUF3231 PF11553.3 ETN98603.1 - 0.3 10.5 2.6 0.63 9.5 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3231) DUF2461 PF09365.5 ETN98604.1 - 0.092 12.1 0.1 0.11 11.8 0.1 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein (DUF2461) NACHT PF05729.7 ETN98605.1 - 2.7e-05 23.9 0.0 5.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Kinesin PF00225.18 ETN98606.1 - 2.1e-07 29.9 5.9 6.4e-07 28.3 4.1 1.8 1 1 0 1 1 1 1 Kinesin motor domain DUF1672 PF07901.6 ETN98606.1 - 0.008 15.1 1.7 0.012 14.6 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1672) CheW PF01584.14 ETN98606.1 - 0.033 13.6 0.0 0.056 12.9 0.0 1.4 1 0 0 1 1 1 0 CheW-like domain Herpes_pp85 PF04637.7 ETN98606.1 - 0.088 11.0 0.0 0.14 10.4 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DnaJ PF00226.26 ETN98607.1 - 4.1e-17 61.6 0.1 1.1e-15 57.0 0.0 2.6 1 1 0 1 1 1 1 DnaJ domain MC1 PF05854.6 ETN98608.1 - 0.35 10.8 16.4 63 3.6 0.0 5.9 1 1 5 6 6 6 0 Non-histone chromosomal protein MC1 Toprim_N PF08275.6 ETN98612.1 - 0.21 11.5 2.3 0.23 11.4 0.8 1.6 2 0 0 2 2 2 0 DNA primase catalytic core, N-terminal domain YL1 PF05764.8 ETN98612.1 - 0.53 9.8 20.5 0.69 9.4 14.2 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Sigma70_ner PF04546.8 ETN98612.1 - 1.8 8.1 16.0 2.4 7.6 11.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Spore_III_AB PF09548.5 ETN98613.1 - 0.0097 15.6 0.6 0.044 13.5 0.1 2.2 2 1 0 2 2 2 1 Stage III sporulation protein AB (spore_III_AB) DUF3899 PF13038.1 ETN98614.1 - 0.68 10.1 4.3 4.3 7.5 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Ras PF00071.17 ETN98615.1 - 7.3e-09 35.2 0.2 2.7e-08 33.3 0.0 1.9 2 0 0 2 2 2 1 Ras family G-alpha PF00503.15 ETN98615.1 - 0.0018 17.0 0.6 0.0028 16.3 0.4 1.5 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETN98615.1 - 0.003 16.8 3.2 0.03 13.5 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family UPF0079 PF02367.12 ETN98615.1 - 0.012 15.2 0.1 0.14 11.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 mRNA_cap_C PF03919.10 ETN98615.1 - 0.075 13.3 3.1 0.1 12.9 1.9 1.4 1 1 0 1 1 1 0 mRNA capping enzyme, C-terminal domain Viral_P18 PF04521.8 ETN98615.1 - 0.13 11.6 1.2 0.21 11.0 0.8 1.3 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein WD40 PF00400.27 ETN98617.1 - 1.1e-16 59.9 13.7 1e-05 25.2 0.1 4.2 4 2 0 4 4 4 3 WD domain, G-beta repeat Imm21 PF15569.1 ETN98617.1 - 0.036 13.8 0.2 0.1 12.3 0.2 1.8 1 0 0 1 1 1 0 Immunity protein 21 BBS2_Mid PF14783.1 ETN98617.1 - 0.047 13.4 0.8 0.38 10.5 0.1 2.2 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region CHZ PF09649.5 ETN98617.1 - 3.5 6.9 5.1 1.5 8.0 1.5 1.9 2 0 0 2 2 2 0 Histone chaperone domain CHZ DUF966 PF06136.8 ETN98619.1 - 0.17 11.2 5.2 0.25 10.7 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DNA_pol_E_B PF04042.11 ETN98622.1 - 0.057 12.6 0.0 0.077 12.2 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B ScpA_ScpB PF02616.9 ETN98623.1 - 0.063 12.8 0.1 0.092 12.3 0.1 1.3 1 0 0 1 1 1 0 ScpA/B protein DUF4181 PF13789.1 ETN98623.1 - 0.095 12.6 0.3 0.2 11.5 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4181) YHYH PF14240.1 ETN98624.1 - 0.037 13.7 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 YHYH protein Sec16 PF12932.2 ETN98624.1 - 0.075 12.9 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region DUF724 PF05266.9 ETN98625.1 - 0.037 13.6 0.5 0.11 12.0 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF724) Sec16 PF12932.2 ETN98625.1 - 0.11 12.4 0.6 0.21 11.5 0.2 1.5 1 1 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region DUF1162 PF06650.7 ETN98626.1 - 5.2e-29 101.3 0.0 6.8e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1162) VWA_2 PF13519.1 ETN98627.1 - 4.8e-17 62.6 0.1 8.2e-17 61.8 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 ETN98627.1 - 7.5e-05 22.5 0.2 0.00019 21.2 0.1 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 ETN98627.1 - 0.0064 16.1 0.0 0.27 10.9 0.0 2.6 2 0 0 2 2 2 1 von Willebrand factor type A domain FAD_binding_8 PF08022.7 ETN98627.1 - 0.028 14.2 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 FAD-binding domain MA3 PF02847.12 ETN98628.1 - 0.0013 18.4 3.7 0.24 11.1 0.6 2.1 1 1 1 2 2 2 2 MA3 domain HEAT_2 PF13646.1 ETN98628.1 - 0.0019 18.4 0.0 0.0025 18.0 0.0 1.2 1 0 0 1 1 1 1 HEAT repeats RNA_binding PF01877.12 ETN98628.1 - 0.019 14.9 0.9 0.71 9.8 0.1 2.3 1 1 0 2 2 2 0 RNA binding DUF2543 PF10820.3 ETN98628.1 - 0.027 14.4 0.1 0.05 13.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2543) Cnd1 PF12717.2 ETN98628.1 - 0.06 13.1 1.0 0.27 11.0 0.2 1.9 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEXIM PF15313.1 ETN98628.1 - 0.081 13.0 2.2 0.11 12.6 1.5 1.2 1 0 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein AAA_15 PF13175.1 ETN98628.1 - 0.27 10.2 11.4 0.32 9.9 7.9 1.0 1 0 0 1 1 1 0 AAA ATPase domain CagZ PF09053.5 ETN98628.1 - 0.34 10.2 4.7 0.4 9.9 3.3 1.1 1 0 0 1 1 1 0 CagZ WD40 PF00400.27 ETN98629.1 - 3.8e-24 83.6 15.7 2.3e-10 39.9 0.5 4.5 5 1 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN98629.1 - 0.00039 18.7 2.6 0.16 10.1 0.0 3.3 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETN98629.1 - 1.4 7.6 9.1 4.8 5.8 5.4 2.3 1 1 1 2 2 2 0 Nup133 N terminal like RNB PF00773.14 ETN98631.1 - 0.0084 15.4 3.5 0.01 15.1 2.4 1.1 1 0 0 1 1 1 1 RNB domain zf-C3HC4_2 PF13923.1 ETN98631.1 - 0.059 13.4 1.3 0.52 10.3 0.9 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_12 PF13424.1 ETN98632.1 - 1.6e-09 37.5 0.1 2.8e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETN98632.1 - 5.3e-07 28.9 0.3 5.3e-07 28.9 0.2 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETN98632.1 - 9.2e-07 28.4 0.3 2.5e-06 27.0 0.2 1.7 1 0 0 1 1 1 1 TPR repeat TPR_8 PF13181.1 ETN98632.1 - 8.7e-06 25.1 1.8 8.7e-06 25.1 1.3 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETN98632.1 - 2.7e-05 23.7 1.0 4.9e-05 22.9 0.1 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETN98632.1 - 0.0019 18.1 0.0 0.0085 15.9 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETN98632.1 - 0.0022 17.6 0.1 0.0048 16.5 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETN98632.1 - 0.088 13.0 0.2 0.44 10.8 0.0 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETN98632.1 - 0.094 13.4 0.0 0.17 12.5 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Kelch_1 PF01344.20 ETN98633.1 - 0.00011 21.6 0.2 0.00062 19.2 0.1 2.0 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETN98633.1 - 0.00032 20.7 0.5 0.0042 17.2 0.1 2.4 1 1 1 2 2 2 1 Kelch motif Kelch_4 PF13418.1 ETN98633.1 - 0.00092 18.9 0.0 0.028 14.1 0.0 2.3 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETN98633.1 - 0.03 14.2 0.9 0.25 11.3 0.1 2.4 3 0 0 3 3 3 0 Kelch motif Kelch_3 PF13415.1 ETN98633.1 - 0.035 14.2 0.0 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 Galactose oxidase, central domain Allexi_40kDa PF05549.6 ETN98633.1 - 0.26 10.5 2.1 0.42 9.8 1.4 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein RVT_1 PF00078.22 ETN98635.1 - 1.4e-08 34.3 0.0 3.5e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Piwi PF02171.12 ETN98636.1 - 2.7e-45 154.6 0.3 1.2e-44 152.4 0.2 1.9 1 1 0 1 1 1 1 Piwi domain Med14 PF08638.6 ETN98637.1 - 0.14 11.3 0.2 0.15 11.2 0.1 1.0 1 0 0 1 1 1 0 Mediator complex subunit MED14 TPR_12 PF13424.1 ETN98638.1 - 7.2e-66 218.1 9.5 1.4e-26 92.1 0.4 2.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETN98638.1 - 3.2e-28 96.7 0.0 1.1e-09 37.9 0.0 4.0 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETN98638.1 - 1.7e-27 94.8 4.7 1.3e-13 50.3 0.5 2.1 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETN98638.1 - 2.1e-27 93.5 20.7 4.6e-11 41.8 1.2 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETN98638.1 - 2.2e-26 89.5 1.9 1.5e-08 33.7 0.0 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETN98638.1 - 2.2e-23 80.2 11.1 1.4e-08 34.0 0.2 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETN98638.1 - 4.4e-23 79.2 26.3 5.9e-08 31.9 1.5 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETN98638.1 - 2e-13 49.3 9.6 7.5e-05 22.6 0.3 4.3 3 3 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETN98638.1 - 5.6e-09 36.4 0.0 0.0033 18.0 0.0 2.4 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETN98638.1 - 8.6e-08 32.1 0.9 0.23 11.9 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 ETN98638.1 - 4.9e-07 29.7 8.7 5.3e-05 23.2 2.3 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 ETN98638.1 - 6.7e-07 29.0 8.3 0.048 13.5 0.1 3.1 3 0 0 3 3 3 3 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.4 ETN98638.1 - 1.4e-06 27.4 0.0 0.0036 16.5 0.0 3.5 3 0 0 3 3 3 1 SHNi-TPR TPR_14 PF13428.1 ETN98638.1 - 1.7e-06 28.1 0.0 0.21 12.3 0.0 3.6 1 1 3 4 4 3 1 Tetratricopeptide repeat SNAP PF14938.1 ETN98638.1 - 5.1e-05 22.5 0.9 0.00017 20.8 0.2 2.1 2 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP Mob_Pre PF01076.14 ETN98638.1 - 6.1e-05 22.7 0.1 0.00014 21.5 0.0 1.5 1 1 1 2 2 2 1 Plasmid recombination enzyme TPR_19 PF14559.1 ETN98638.1 - 0.00015 22.0 0.3 0.024 14.9 0.0 2.8 1 1 2 3 3 3 2 Tetratricopeptide repeat Sel1 PF08238.7 ETN98638.1 - 0.00044 20.7 5.2 0.71 10.5 0.1 4.0 4 0 0 4 4 4 1 Sel1 repeat Ten1_2 PF15490.1 ETN98638.1 - 0.00071 19.1 0.0 2.2 7.8 0.0 3.0 1 1 2 3 3 3 1 Telomere-capping, CST complex subunit PPR PF01535.15 ETN98638.1 - 0.0029 17.4 5.7 0.022 14.7 0.1 3.7 4 0 0 4 4 4 1 PPR repeat DUF3568 PF12092.3 ETN98638.1 - 0.0034 17.1 0.0 0.72 9.5 0.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF3568) RPN7 PF10602.4 ETN98638.1 - 0.0044 16.4 2.4 0.32 10.3 0.1 2.3 1 1 1 2 2 2 1 26S proteasome subunit RPN7 DUF2225 PF09986.4 ETN98638.1 - 0.006 16.0 1.2 1.5 8.2 0.1 2.1 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_3 PF07720.7 ETN98638.1 - 0.012 15.3 0.2 0.012 15.3 0.1 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF2642 PF10842.3 ETN98638.1 - 0.012 15.0 0.0 15 5.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2642) FATC PF02260.15 ETN98638.1 - 0.014 14.7 0.3 4.8 6.6 0.0 3.0 3 0 0 3 3 3 0 FATC domain A2M_recep PF07677.9 ETN98638.1 - 0.017 15.2 2.5 0.52 10.5 0.5 2.2 1 1 1 2 2 2 0 A-macroglobulin receptor ATP-synt_E_2 PF08112.6 ETN98638.1 - 0.021 14.8 10.5 1.6 8.8 0.0 3.3 2 1 1 3 3 3 0 ATP synthase epsilon subunit Y1_Tnp PF01797.11 ETN98638.1 - 0.026 14.4 0.9 3.7 7.4 0.1 2.5 1 1 1 3 3 3 0 Transposase IS200 like Musclin PF11037.3 ETN98638.1 - 0.03 13.9 0.0 8.5 6.0 0.0 2.8 3 0 0 3 3 3 0 Insulin-resistance promoting peptide in skeletal muscle DUF1498 PF07385.7 ETN98638.1 - 0.045 12.8 0.1 7.8 5.5 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1498) PPR_2 PF13041.1 ETN98638.1 - 0.35 10.8 0.1 0.35 10.8 0.0 2.0 3 0 0 3 3 2 0 PPR repeat family RTP PF02334.11 ETN98638.1 - 1.1 9.2 5.8 3.1 7.7 1.0 2.7 1 1 1 3 3 3 0 Replication terminator protein Fis1_TPR_C PF14853.1 ETN98638.1 - 2.4 8.1 8.5 6.7 6.6 0.2 3.2 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Phytochelatin_C PF09328.5 ETN98641.1 - 0.09 12.2 0.1 0.093 12.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1984) Cpn60_TCP1 PF00118.19 ETN98642.1 - 1e-49 169.5 1.0 1.8e-40 138.9 0.2 2.1 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family Synapsin_C PF02750.9 ETN98642.1 - 0.1 11.7 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 Synapsin, ATP binding domain Phosducin PF02114.11 ETN98643.1 - 2.3e-06 26.5 0.0 3.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Phosducin Astro_capsid PF03115.9 ETN98644.1 - 0.17 10.0 4.7 0.2 9.8 3.3 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor WD40 PF00400.27 ETN98645.1 - 2.5e-27 93.7 12.4 3e-11 42.7 0.0 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN98645.1 - 2.8e-09 35.6 0.3 0.00021 19.5 0.1 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETN98645.1 - 0.0055 16.0 3.2 0.01 15.2 1.6 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4221) TBCC PF07986.7 ETN98645.1 - 0.02 14.2 0.6 0.028 13.8 0.4 1.2 1 0 0 1 1 1 0 Tubulin binding cofactor C Nucleoporin_N PF08801.6 ETN98645.1 - 0.04 12.6 1.1 0.88 8.2 0.3 2.0 1 1 1 2 2 2 0 Nup133 N terminal like WD40 PF00400.27 ETN98646.1 - 1.7e-18 65.7 11.4 9.5e-10 37.9 0.4 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETN98646.1 - 0.002 16.3 3.3 0.16 10.0 0.5 2.1 1 1 0 2 2 2 2 Nucleoporin Nup120/160 Gp58 PF07902.6 ETN98646.1 - 0.014 13.6 1.6 0.019 13.1 1.1 1.2 1 0 0 1 1 1 0 gp58-like protein Lipoprotein_3 PF00938.12 ETN98646.1 - 0.039 13.7 4.0 0.078 12.7 2.8 1.5 1 0 0 1 1 1 0 Lipoprotein DUF1801 PF08818.6 ETN98646.1 - 0.06 13.4 0.5 0.45 10.6 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DU1801) CENP-K PF11802.3 ETN98646.1 - 0.47 9.6 5.7 0.59 9.3 3.9 1.1 1 0 0 1 1 1 0 Centromere-associated protein K CorA PF01544.13 ETN98647.1 - 0.12 11.4 4.9 0.13 11.2 3.4 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Transposase_22 PF02994.9 ETN98647.1 - 0.33 9.3 13.0 0.36 9.2 9.0 1.1 1 0 0 1 1 1 0 L1 transposable element TMPIT PF07851.8 ETN98647.1 - 2 7.4 12.5 2.1 7.3 8.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein GvpK PF05121.7 ETN98647.1 - 3.4 7.5 7.6 0.73 9.6 2.4 1.9 1 1 1 2 2 2 0 Gas vesicle protein K DUF3573 PF12097.3 ETN98647.1 - 4.8 5.6 12.6 4.7 5.7 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Inhibitor_I29 PF08246.7 ETN98647.1 - 8.5 6.7 12.9 53 4.1 9.0 2.3 1 1 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) YPEB PF14620.1 ETN98648.1 - 0.14 11.1 7.1 0.17 10.8 4.9 1.1 1 0 0 1 1 1 0 YpeB sporulation R-HINP1I PF11463.3 ETN98648.1 - 3.1 7.1 7.5 4.2 6.7 5.2 1.2 1 0 0 1 1 1 0 R.HinP1I restriction endonuclease Rab3-GTPase_cat PF13890.1 ETN98649.1 - 9e-08 31.6 1.0 1.4e-07 31.0 0.7 1.3 1 0 0 1 1 1 1 Rab3 GTPase-activating protein catalytic subunit Archease PF01951.11 ETN98650.1 - 0.086 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Archease protein family (MTH1598/TM1083) zf-CCHC_4 PF14392.1 ETN98651.1 - 0.0042 16.7 3.2 0.43 10.2 0.4 2.5 1 1 1 2 2 2 2 Zinc knuckle Herpes_LMP1 PF05297.6 ETN98651.1 - 0.041 12.8 1.1 0.047 12.6 0.7 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) UPF0180 PF03698.8 ETN98651.1 - 0.14 12.0 0.8 0.33 10.8 0.0 2.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0180) zf-CCHC PF00098.18 ETN98651.1 - 6.6 6.8 8.2 0.93 9.5 0.3 2.7 2 1 0 2 2 2 0 Zinc knuckle YlbE PF14003.1 ETN98652.1 - 0.088 12.8 0.3 6.7 6.8 0.0 3.0 3 0 0 3 3 3 0 YlbE-like protein Peptidase_M9_N PF08453.5 ETN98652.1 - 0.1 11.9 1.2 2.3 7.5 0.1 2.4 3 0 0 3 3 3 0 Peptidase family M9 N-terminal UBA PF00627.26 ETN98654.1 - 0.0042 16.8 0.1 0.011 15.5 0.0 1.7 2 0 0 2 2 2 1 UBA/TS-N domain CUE PF02845.11 ETN98654.1 - 0.0099 15.3 0.3 0.024 14.0 0.1 1.8 2 1 0 2 2 2 1 CUE domain CAML PF14963.1 ETN98654.1 - 0.057 12.7 0.4 0.061 12.6 0.3 1.0 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand BSMAP PF12280.3 ETN98654.1 - 0.063 13.1 0.1 0.065 13.1 0.1 1.1 1 0 0 1 1 1 0 Brain specific membrane anchored protein DUF106 PF01956.11 ETN98654.1 - 0.1 12.0 0.3 0.15 11.5 0.2 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF1283 PF06932.6 ETN98654.1 - 0.11 12.5 1.3 0.13 12.2 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1283) NAD_kinase PF01513.16 ETN98654.1 - 0.11 11.2 0.7 0.14 10.9 0.5 1.0 1 0 0 1 1 1 0 ATP-NAD kinase Iron_permease PF04120.7 ETN98654.1 - 0.88 9.1 2.8 1 8.9 1.9 1.1 1 0 0 1 1 1 0 Low affinity iron permease RNase_H2-Ydr279 PF09468.5 ETN98654.1 - 2.1 7.4 7.3 2.2 7.4 5.1 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) WD40 PF00400.27 ETN98656.1 - 1.4e-07 31.0 0.2 0.00038 20.2 0.0 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat PUB PF09409.5 ETN98657.1 - 0.00037 20.2 0.3 0.00094 18.8 0.2 1.7 1 1 0 1 1 1 1 PUB domain WD40 PF00400.27 ETN98659.1 - 7.3e-13 47.8 10.1 4.2e-06 26.4 0.7 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETN98659.1 - 3.2e-05 22.2 1.2 0.00079 17.6 0.2 2.0 1 1 0 2 2 2 2 Nucleoporin Nup120/160 Ricin_B_lectin PF00652.17 ETN98659.1 - 0.11 12.5 4.1 0.15 12.1 2.9 1.1 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain GlutR_dimer PF00745.15 ETN98660.1 - 0.0058 16.5 0.5 0.46 10.4 0.1 2.3 1 1 2 3 3 3 3 Glutamyl-tRNAGlu reductase, dimerisation domain CUE PF02845.11 ETN98660.1 - 0.047 13.1 0.1 0.15 11.5 0.0 1.9 1 0 0 1 1 1 0 CUE domain DUF1904 PF08921.6 ETN98660.1 - 0.14 12.2 3.3 0.19 11.8 0.2 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1904) SdrG_C_C PF10425.4 ETN98661.1 - 0.048 13.6 4.5 0.55 10.1 0.1 2.1 1 1 1 2 2 2 0 C-terminus of bacterial fibrinogen-binding adhesin DUF2629 PF10945.3 ETN98662.1 - 0.052 12.8 0.1 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2629) Kinesin PF00225.18 ETN98662.1 - 0.067 11.8 0.4 0.08 11.6 0.3 1.1 1 0 0 1 1 1 0 Kinesin motor domain PUB PF09409.5 ETN98663.1 - 4.1e-08 32.8 0.0 1e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 PUB domain DUF503 PF04456.7 ETN98663.1 - 0.032 13.8 0.3 0.074 12.6 0.1 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF503) DUF912 PF06024.7 ETN98663.1 - 2.2 8.3 6.0 0.4 10.7 1.3 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ZZ PF00569.12 ETN98664.1 - 0.014 14.9 0.5 0.04 13.4 0.3 1.8 1 0 0 1 1 1 0 Zinc finger, ZZ type TAFH PF07531.9 ETN98664.1 - 0.017 14.7 0.2 0.048 13.2 0.2 1.7 1 0 0 1 1 1 0 NHR1 homology to TAF Nnf1 PF03980.9 ETN98664.1 - 0.029 14.3 0.3 0.029 14.3 0.2 2.5 2 1 0 2 2 2 0 Nnf1 KxDL PF10241.4 ETN98664.1 - 0.11 12.4 8.9 0.92 9.4 0.4 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein FlxA PF14282.1 ETN98664.1 - 0.62 10.0 11.3 0.14 12.1 4.4 2.2 2 0 0 2 2 2 0 FlxA-like protein Exo_endo_phos_2 PF14529.1 ETN98665.1 - 4.6e-07 29.4 0.3 7.2e-07 28.8 0.2 1.3 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Kelch_1 PF01344.20 ETN98666.1 - 3.2e-06 26.5 0.6 4.2e-05 23.0 0.1 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.10 ETN98666.1 - 4.3e-05 23.0 0.3 0.0011 18.6 0.1 2.3 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.1 ETN98666.1 - 9e-05 22.1 0.3 0.0097 15.6 0.0 2.3 1 1 1 2 2 2 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETN98666.1 - 0.0013 18.8 0.0 0.0042 17.2 0.0 1.8 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETN98666.1 - 0.0013 18.8 2.8 0.035 14.2 0.2 2.5 1 1 1 2 2 2 1 Kelch motif Kelch_5 PF13854.1 ETN98666.1 - 0.0026 17.6 0.3 0.039 13.9 0.1 2.2 2 0 0 2 2 2 1 Kelch motif DUF2947 PF11163.3 ETN98666.1 - 0.22 11.1 3.9 3.4 7.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2947) RNA_pol_Rpb5_C PF01191.14 ETN98667.1 - 0.056 13.0 0.2 0.097 12.2 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain PRE_C2HC PF07530.6 ETN98667.1 - 0.088 12.7 0.2 0.24 11.3 0.1 1.8 1 1 0 1 1 1 0 Associated with zinc fingers Phos_pyr_kin PF08543.7 ETN98668.1 - 4.9e-12 45.5 0.0 6.8e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 ETN98668.1 - 1.6e-07 30.7 0.0 2.7e-05 23.4 0.0 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Glyco_hydro_3_C PF01915.17 ETN98670.1 - 1.8e-12 47.2 0.0 2.4e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain TPR_12 PF13424.1 ETN98671.1 - 9.9e-34 115.1 11.5 8.2e-20 70.5 1.5 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETN98671.1 - 2.9e-18 65.1 0.0 1.2e-07 31.4 0.0 3.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETN98671.1 - 4.1e-17 60.5 4.9 4.4e-05 22.9 0.1 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETN98671.1 - 7.9e-17 60.6 7.8 9.4e-11 41.2 1.9 2.1 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETN98671.1 - 5.6e-16 57.3 17.2 2.6e-08 33.1 2.6 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETN98671.1 - 3.5e-13 48.3 12.7 7.9e-05 22.2 0.5 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETN98671.1 - 3.9e-13 48.1 19.3 4.7e-06 26.0 2.3 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETN98671.1 - 1.2e-09 38.5 0.5 0.00011 22.7 0.4 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETN98671.1 - 6e-08 32.6 2.1 0.03 14.7 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETN98671.1 - 2.1e-06 27.4 8.1 0.012 15.7 0.3 3.3 2 2 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETN98671.1 - 2.3e-06 27.7 0.1 1.1 10.0 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 ETN98671.1 - 4.4e-06 26.7 3.4 2e-05 24.6 2.2 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETN98671.1 - 0.0042 17.3 3.2 0.14 12.5 0.4 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_3 PF07720.7 ETN98671.1 - 0.013 15.2 5.1 0.044 13.5 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat ATP-synt_E_2 PF08112.6 ETN98671.1 - 0.044 13.8 9.6 0.85 9.7 0.2 3.3 2 1 1 3 3 3 0 ATP synthase epsilon subunit DUF2582 PF10771.4 ETN98671.1 - 0.17 11.7 0.9 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2582) MIT PF04212.13 ETN98671.1 - 1.3 8.9 5.1 8.1 6.4 0.5 2.9 2 2 1 3 3 3 0 MIT (microtubule interacting and transport) domain Ubiq-assoc PF09145.5 ETN98671.1 - 1.5 8.7 5.5 1.4 8.8 0.4 3.1 1 1 2 3 3 3 0 Ubiquitin-associated SPRY PF00622.23 ETN98672.1 - 2.4e-09 37.3 0.3 4.3e-09 36.5 0.2 1.3 1 0 0 1 1 1 1 SPRY domain Cupin_3 PF05899.7 ETN98672.1 - 0.095 12.0 0.3 0.23 10.8 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF861) AAA_5 PF07728.9 ETN98673.1 - 0.0055 16.4 0.0 0.024 14.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DASH_Dad2 PF08654.5 ETN98674.1 - 0.068 13.1 0.6 0.12 12.3 0.4 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad2 CcdB PF01845.12 ETN98674.1 - 0.099 12.5 0.3 0.21 11.5 0.2 1.5 1 0 0 1 1 1 0 CcdB protein Zn_clus PF00172.13 ETN98675.1 - 0.0088 15.9 1.6 0.015 15.1 1.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Trp_dioxygenase PF03301.8 ETN98676.1 - 0.034 13.2 0.0 0.098 11.7 0.0 1.7 2 0 0 2 2 2 0 Tryptophan 2,3-dioxygenase DUF2431 PF10354.4 ETN98677.1 - 4e-05 23.6 0.3 5.7e-05 23.1 0.2 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) WASH-7_C PF14746.1 ETN98677.1 - 0.047 13.2 0.2 0.063 12.8 0.1 1.2 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal DNA_pol3_gamma3 PF12169.3 ETN98677.1 - 0.057 13.1 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III HTH_AsnC-type PF13404.1 ETN98678.1 - 0.23 11.0 0.8 0.54 9.8 0.6 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain DUF2370 PF10176.4 ETN98679.1 - 0.17 11.2 1.9 0.19 11.0 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF1980 PF09323.5 ETN98679.1 - 2 8.1 7.6 2.5 7.7 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Choline_sulf_C PF12411.3 ETN98680.1 - 0.005 16.6 0.1 0.017 14.9 0.1 1.9 3 0 0 3 3 3 1 Choline sulfatase enzyme C terminal WD40 PF00400.27 ETN98682.1 - 1e-06 28.3 0.1 5e-06 26.1 0.1 2.0 2 0 0 2 2 2 1 WD domain, G-beta repeat WD40 PF00400.27 ETN98684.1 - 5.9e-31 105.2 5.2 1.5e-09 37.3 0.1 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN98684.1 - 7.5e-05 21.0 1.1 0.092 10.8 0.0 2.9 1 1 1 3 3 3 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETN98684.1 - 0.019 14.7 0.8 0.075 12.8 0.0 2.1 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Marek_SORF3 PF07153.6 ETN98684.1 - 0.04 12.5 0.5 2.9 6.4 0.0 2.2 1 1 1 2 2 2 0 Marek's disease-like virus SORF3 protein SBP56 PF05694.6 ETN98684.1 - 0.041 12.3 0.1 0.12 10.8 0.0 1.7 1 1 1 2 2 2 0 56kDa selenium binding protein (SBP56) WD40 PF00400.27 ETN98687.1 - 1.1e-12 47.2 5.9 2.7e-07 30.2 0.6 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETN98687.1 - 0.021 12.9 0.1 0.85 7.6 0.0 2.0 1 1 0 2 2 2 0 Nucleoporin Nup120/160 YoqO PF14037.1 ETN98688.1 - 0.29 11.2 5.9 1.6 8.8 0.1 2.4 2 1 1 3 3 3 0 YoqO-like protein Ank PF00023.25 ETN98689.1 - 1.3e-08 34.1 0.1 6.9e-08 31.9 0.1 2.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 ETN98689.1 - 5.4e-08 33.0 0.0 3e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETN98689.1 - 1.2e-07 31.7 0.1 2.6e-07 30.6 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETN98689.1 - 3.8e-07 29.7 0.8 2.6e-06 27.1 0.2 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 ETN98689.1 - 1.7e-06 28.3 0.2 4e-06 27.1 0.2 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) HU-DNA_bdg PF14848.1 ETN98689.1 - 0.094 12.4 0.4 0.18 11.5 0.3 1.4 1 0 0 1 1 1 0 DNA-binding domain Bap31 PF05529.7 ETN98691.1 - 2 7.8 7.8 2.8 7.3 5.4 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF4355 PF14265.1 ETN98691.1 - 2.5 8.0 18.8 3.2 7.7 13.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Band_3_cyto PF07565.8 ETN98691.1 - 7.4 6.0 10.2 12 5.2 7.1 1.5 1 1 0 1 1 1 0 Band 3 cytoplasmic domain DUF1183 PF06682.7 ETN98693.1 - 0.011 15.3 1.2 0.013 15.1 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF572 PF04502.8 ETN98693.1 - 0.015 14.5 2.7 0.019 14.2 1.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ndc1_Nup PF09531.5 ETN98693.1 - 0.041 12.3 1.8 0.046 12.1 1.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CDC45 PF02724.9 ETN98693.1 - 0.056 11.4 3.8 0.062 11.3 2.7 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2796 PF10986.3 ETN98693.1 - 0.057 13.4 2.8 0.067 13.1 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) eIF-3c_N PF05470.7 ETN98693.1 - 0.11 10.5 4.8 0.13 10.3 3.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Nop14 PF04147.7 ETN98693.1 - 0.32 8.8 6.0 0.33 8.7 4.2 1.0 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.5 ETN98693.1 - 1.9 8.4 6.7 2.2 8.2 4.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PBP1_TM PF14812.1 ETN98693.1 - 6.9 7.0 6.9 12 6.2 4.8 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ank_2 PF12796.2 ETN98695.1 - 2.6e-10 40.4 0.3 0.0033 17.7 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETN98695.1 - 3e-06 27.2 0.0 1.4 9.2 0.0 5.5 4 2 3 7 7 7 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETN98695.1 - 2.1e-05 24.8 0.0 0.042 14.3 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.25 ETN98695.1 - 0.00099 18.8 0.2 2.4 8.1 0.0 3.9 5 0 0 5 5 5 2 Ankyrin repeat FAD_binding_6 PF00970.19 ETN98697.1 - 2.6e-22 78.8 0.0 1.1e-21 76.7 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 ETN98697.1 - 5.3e-11 43.0 0.1 3.4e-10 40.4 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 ETN98697.1 - 2.3e-06 27.6 0.9 3.8e-06 26.9 0.2 1.7 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Acetyltransf_4 PF13420.1 ETN98697.1 - 0.17 11.7 2.0 0.34 10.8 0.5 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain EF-hand_7 PF13499.1 ETN98698.1 - 5.5e-05 23.2 0.4 0.00025 21.1 0.3 2.2 1 1 0 1 1 1 1 EF-hand domain pair TryThrA_C PF12319.3 ETN98698.1 - 0.00068 18.8 0.8 0.00068 18.8 0.5 2.1 2 0 0 2 2 2 2 Tryptophan-Threonine-rich plasmodium antigen C terminal EF-hand_1 PF00036.27 ETN98698.1 - 0.0044 16.2 0.1 0.011 14.9 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 ETN98698.1 - 0.0049 16.6 0.1 0.015 15.1 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 ETN98698.1 - 0.0054 16.0 0.1 0.013 14.7 0.0 1.7 1 0 0 1 1 1 1 EF hand DEAD PF00270.24 ETN98699.1 - 0.00016 21.2 0.0 0.00031 20.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.11 ETN98699.1 - 0.015 14.5 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.10 ETN98699.1 - 0.045 13.5 6.6 0.25 11.1 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit TIP49 PF06068.8 ETN98699.1 - 0.05 12.3 0.0 0.077 11.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_19 PF13245.1 ETN98699.1 - 0.087 12.5 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Med3 PF11593.3 ETN98699.1 - 0.14 11.3 44.6 0.2 10.8 30.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AAA_18 PF13238.1 ETN98699.1 - 0.38 11.0 0.1 0.38 11.0 0.1 3.1 2 2 0 2 2 2 0 AAA domain SprA-related PF12118.3 ETN98699.1 - 1.3 8.2 18.4 0.069 12.4 4.7 2.3 2 0 0 2 2 2 0 SprA-related family Ribosomal_L34 PF00468.12 ETN98700.1 - 0.61 9.8 5.2 7.3 6.3 0.6 2.9 1 1 2 3 3 3 0 Ribosomal protein L34 dDENN PF03455.14 ETN98701.1 - 1.1e-05 25.4 4.0 1.7e-05 24.8 2.8 1.3 1 0 0 1 1 1 1 dDENN domain DUF4512 PF14975.1 ETN98702.1 - 0.65 10.8 3.4 2.3 9.0 0.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4512) MFMR PF07777.6 ETN98702.1 - 3.4 7.5 14.0 3.3 7.5 5.6 2.3 2 0 0 2 2 2 0 G-box binding protein MFMR DUF2769 PF10967.3 ETN98703.1 - 0.38 11.1 8.8 4.7 7.5 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2769) Reo_sigmaC PF04582.7 ETN98704.1 - 2.1 7.4 19.3 0.76 8.8 5.5 2.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Macoilin PF09726.4 ETN98704.1 - 3.6 5.7 74.8 4.8 5.3 51.8 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF1376 PF07120.6 ETN98704.1 - 6 7.0 10.9 0.27 11.3 1.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1376) FAM176 PF14851.1 ETN98708.1 - 0.11 12.1 0.7 0.16 11.6 0.5 1.2 1 0 0 1 1 1 0 FAM176 family DUF4611 PF15387.1 ETN98708.1 - 0.18 11.9 2.6 0.26 11.4 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 ETN98708.1 - 0.19 11.2 4.4 0.29 10.6 3.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 ETN98708.1 - 1 9.6 6.6 1.6 9.0 4.6 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 ETN98708.1 - 2.8 8.3 10.3 0.068 13.4 2.0 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Transketolase_N PF00456.16 ETN98709.1 - 0.03 13.1 0.2 0.054 12.3 0.1 1.4 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain HEAT_2 PF13646.1 ETN98710.1 - 4.7e-05 23.5 0.0 6.1e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 HEAT repeats HEAT PF02985.17 ETN98710.1 - 0.0031 17.4 0.0 2.2 8.6 0.0 2.4 2 0 0 2 2 2 2 HEAT repeat RUN PF02759.14 ETN98710.1 - 0.043 13.5 0.8 0.33 10.7 0.5 2.1 1 1 0 1 1 1 0 RUN domain HEAT_EZ PF13513.1 ETN98710.1 - 0.15 12.5 0.0 0.49 10.9 0.0 1.8 2 0 0 2 2 2 0 HEAT-like repeat HEAT_2 PF13646.1 ETN98711.1 - 1e-30 105.8 0.1 7.9e-08 32.4 0.0 3.5 1 1 4 5 5 5 5 HEAT repeats HEAT PF02985.17 ETN98711.1 - 2.3e-18 64.5 0.1 0.0062 16.5 0.0 5.5 5 0 0 5 5 5 5 HEAT repeat Vac14_Fab1_bd PF12755.2 ETN98711.1 - 7.8e-12 45.4 1.3 0.0092 16.3 0.0 4.3 1 1 4 5 5 5 4 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 ETN98711.1 - 3.5e-09 36.8 0.0 0.0036 17.7 0.0 5.0 1 1 4 5 5 5 2 HEAT-like repeat DUF2435 PF10363.4 ETN98711.1 - 8.2e-09 35.2 1.3 2.6e-05 24.0 0.1 3.3 2 1 1 3 3 3 1 Protein of unknown function (DUF2435) TIP120 PF08623.5 ETN98711.1 - 1.3e-08 34.5 5.1 0.085 12.4 0.1 3.6 1 1 3 4 4 4 3 TATA-binding protein interacting (TIP20) Cnd1 PF12717.2 ETN98711.1 - 2.4e-05 24.2 1.5 0.055 13.3 0.1 2.8 1 1 2 3 3 3 3 non-SMC mitotic condensation complex subunit 1 NLE PF08154.7 ETN98711.1 - 4e-05 23.5 3.9 3.7 7.6 0.1 5.1 3 2 1 5 5 5 1 NLE (NUC135) domain HNH_5 PF14279.1 ETN98711.1 - 8.1e-05 22.5 3.9 0.2 11.7 0.1 3.2 3 0 0 3 3 3 2 HNH endonuclease Adaptin_N PF01602.15 ETN98711.1 - 0.00045 18.6 1.9 0.029 12.6 0.2 1.9 1 1 1 2 2 2 1 Adaptin N terminal region DUF3554 PF12074.3 ETN98711.1 - 0.00088 18.7 0.3 1.6 8.0 0.0 3.1 1 1 0 3 3 3 2 Domain of unknown function (DUF3554) TAN PF11640.3 ETN98711.1 - 0.0015 18.2 3.5 0.019 14.7 1.0 3.3 2 1 2 4 4 4 1 Telomere-length maintenance and DNA damage repair CRM1_C PF08767.6 ETN98711.1 - 0.0044 15.9 1.3 5.5 5.8 0.1 3.4 1 1 2 4 4 4 0 CRM1 C terminal DUF3826 PF12875.2 ETN98711.1 - 0.011 15.4 2.1 0.087 12.5 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3826) Activator-TraM PF11657.3 ETN98711.1 - 0.013 15.0 0.3 0.15 11.5 0.0 2.6 2 1 0 2 2 2 0 Transcriptional activator TraM MOR2-PAG1_C PF14225.1 ETN98711.1 - 0.014 15.1 0.4 8.4 6.0 0.0 3.1 1 1 1 3 3 3 0 Cell morphogenesis C-terminal DrsE PF02635.10 ETN98711.1 - 0.017 15.1 0.2 0.22 11.5 0.1 2.4 2 0 0 2 2 2 0 DsrE/DsrF-like family Inhibitor_I9 PF05922.11 ETN98711.1 - 0.028 14.9 0.4 18 5.9 0.0 3.4 3 0 0 3 3 3 0 Peptidase inhibitor I9 DUF3349 PF11829.3 ETN98711.1 - 0.03 14.7 1.6 14 6.2 0.1 4.3 1 1 3 4 4 4 0 Protein of unknown function (DUF3349) Imm39 PF15600.1 ETN98711.1 - 0.06 13.1 6.2 4.8 6.9 0.2 3.5 1 1 2 3 3 3 0 Immunity protein 39 CLASP_N PF12348.3 ETN98711.1 - 0.11 11.8 0.1 7.8 5.7 0.0 2.2 1 1 1 2 2 2 0 CLASP N terminal UME PF08064.8 ETN98711.1 - 0.11 12.5 0.3 8.5 6.3 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain Glycos_trans_3N PF02885.12 ETN98711.1 - 0.12 11.9 0.3 13 5.4 0.0 3.8 4 0 0 4 4 4 0 Glycosyl transferase family, helical bundle domain Syntaphilin PF15290.1 ETN98711.1 - 0.22 10.9 1.9 5.5 6.3 0.1 2.3 1 1 1 2 2 2 0 Golgi-localised syntaxin-1-binding clamp dsDNA_bind PF01984.15 ETN98711.1 - 2.4 8.2 6.1 47 4.0 0.1 4.4 3 2 1 5 5 5 0 Double-stranded DNA-binding domain Imm2 PF14426.1 ETN98711.1 - 3.9 7.5 7.3 11 6.0 0.2 3.7 3 1 1 4 4 3 0 Immunity protein Imm2 DUF2758 PF10957.3 ETN98711.1 - 4 7.3 5.6 67 3.4 0.1 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF2758) AAA_22 PF13401.1 ETN98712.1 - 4.6e-05 23.5 0.0 0.0005 20.2 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA PF00004.24 ETN98712.1 - 0.0011 19.2 0.0 0.0027 17.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_pol_Rpb4 PF03874.11 ETN98712.1 - 0.015 15.3 2.3 0.15 12.0 0.1 2.6 3 0 0 3 3 3 0 RNA polymerase Rpb4 AAA_5 PF07728.9 ETN98712.1 - 0.096 12.4 0.1 1.8 8.2 0.1 2.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Ank_3 PF13606.1 ETN98714.1 - 0.0038 17.3 0.2 0.032 14.4 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 ETN98714.1 - 0.024 15.1 0.1 0.089 13.3 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETN98714.1 - 0.09 13.1 0.8 0.37 11.1 0.6 2.2 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) PqiA PF04403.8 ETN98716.1 - 0.0028 17.2 0.5 0.14 11.7 0.2 2.1 2 0 0 2 2 2 2 Paraquat-inducible protein A ERAP1_C PF11838.3 ETN98717.1 - 2.8e-28 99.0 0.1 3.6e-28 98.7 0.1 1.1 1 0 0 1 1 1 1 ERAP1-like C-terminal domain HEAT_2 PF13646.1 ETN98717.1 - 0.0064 16.7 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 HEAT repeats NAD_binding_9 PF13454.1 ETN98717.1 - 0.073 12.8 0.1 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding PDDEXK_1 PF12705.2 ETN98717.1 - 0.11 11.8 0.3 0.18 11.1 0.2 1.5 1 1 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Phage_min_tail PF05939.8 ETN98718.1 - 0.08 12.9 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Phage minor tail protein TPR_11 PF13414.1 ETN98720.1 - 0.0085 15.7 0.1 0.017 14.7 0.1 1.4 1 0 0 1 1 1 1 TPR repeat PIG-X PF08320.7 ETN98721.1 - 0.027 13.7 0.2 0.032 13.5 0.1 1.1 1 0 0 1 1 1 0 PIG-X / PBN1 YqfQ PF14181.1 ETN98721.1 - 1.2 9.1 5.8 1.5 8.7 4.0 1.1 1 0 0 1 1 1 0 YqfQ-like protein DUF3987 PF13148.1 ETN98721.1 - 1.4 7.3 4.3 1.6 7.1 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Cupin_8 PF13621.1 ETN98724.1 - 0.024 14.1 0.5 0.025 14.0 0.3 1.3 1 0 0 1 1 1 0 Cupin-like domain Baculo_PEP_N PF04512.7 ETN98724.1 - 0.039 13.9 0.3 0.29 11.1 0.2 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, N terminus v110 PF01639.12 ETN98724.1 - 0.59 9.7 5.1 0.81 9.2 0.1 2.3 2 0 0 2 2 2 0 Viral family 110 WD40 PF00400.27 ETN98727.1 - 9.8e-15 53.7 1.2 6.6e-12 44.8 0.2 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Secretin_N_2 PF07655.8 ETN98730.1 - 3.1 8.2 24.5 2.8 8.4 14.9 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain Ndc1_Nup PF09531.5 ETN98730.1 - 4.1 5.7 17.8 5.5 5.2 12.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup U-box PF04564.10 ETN98731.1 - 2.1e-08 33.9 0.1 5.5e-08 32.6 0.1 1.8 1 1 0 1 1 1 1 U-box domain LUC7 PF03194.10 ETN98731.1 - 0.12 11.9 1.6 0.14 11.6 1.1 1.2 1 0 0 1 1 1 0 LUC7 N_terminus RPW8 PF05659.6 ETN98731.1 - 0.16 11.5 4.2 0.26 10.8 2.9 1.4 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 ArfGap PF01412.13 ETN98732.1 - 3.3e-08 33.2 0.0 8.1e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.24 ETN98732.1 - 3.2e-05 24.0 3.5 0.017 15.3 0.1 2.9 2 1 0 2 2 2 2 PH domain TcdB_N PF12918.2 ETN98733.1 - 0.029 14.4 0.2 0.058 13.4 0.1 1.5 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain ubiquitin PF00240.18 ETN98735.1 - 2.7e-69 228.4 6.1 3.7e-34 115.9 0.4 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 ETN98735.1 - 1.2e-42 143.3 5.8 9.6e-21 73.2 0.4 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 ETN98735.1 - 2.2e-14 53.4 1.6 1.4e-05 25.2 0.1 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain Telomere_Sde2 PF13019.1 ETN98735.1 - 4.8e-10 39.3 0.0 0.0009 18.9 0.0 2.0 2 0 0 2 2 2 2 Telomere stability and silencing Rad60-SLD_2 PF13881.1 ETN98735.1 - 1.8e-08 34.2 0.3 0.0088 15.9 0.0 2.7 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 ETN98735.1 - 9.3e-07 28.9 0.1 0.045 13.9 0.0 2.2 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 ETN98735.1 - 2.6e-06 27.2 0.6 0.071 13.0 0.0 2.2 2 0 0 2 2 2 2 GLUT4 regulating protein TUG DUF2870 PF11069.3 ETN98735.1 - 3.2e-05 23.8 0.1 0.49 10.4 0.0 3.0 2 2 1 3 3 3 2 Protein of unknown function (DUF2870) USP7_C2 PF14533.1 ETN98735.1 - 8.2e-05 22.1 0.4 0.3 10.5 0.0 2.1 1 1 0 2 2 2 2 Ubiquitin-specific protease C-terminal eRF1_1 PF03463.10 ETN98735.1 - 0.00039 19.9 0.3 0.46 10.0 0.0 3.1 1 1 2 3 3 3 2 eRF1 domain 1 PI3K_rbd PF00794.13 ETN98735.1 - 0.0019 18.1 0.4 1.2 9.0 0.0 2.4 2 0 0 2 2 2 2 PI3-kinase family, ras-binding domain FlgD_ig PF13860.1 ETN98735.1 - 0.0041 16.8 0.2 3.5 7.4 0.0 2.4 2 0 0 2 2 2 2 FlgD Ig-like domain FERM_N PF09379.5 ETN98735.1 - 0.0054 16.7 1.6 6.4 6.9 0.1 3.4 2 2 0 2 2 2 2 FERM N-terminal domain GABP-alpha PF11620.3 ETN98735.1 - 0.014 15.3 0.5 5 7.1 0.0 2.1 2 0 0 2 2 2 0 GA-binding protein alpha chain CTDII PF01556.13 ETN98735.1 - 0.019 14.8 4.2 1.2 9.1 0.2 2.2 1 1 1 2 2 2 0 DnaJ C terminal domain IGR PF09597.5 ETN98735.1 - 0.064 13.1 0.0 17 5.3 0.0 2.4 2 0 0 2 2 2 0 IGR protein motif Plexin_cytopl PF08337.7 ETN98735.1 - 0.086 11.1 1.8 4.7 5.4 0.2 3.2 3 1 0 3 3 3 0 Plexin cytoplasmic RasGAP domain CpeS PF09367.5 ETN98735.1 - 0.15 11.9 0.1 15 5.4 0.0 2.1 2 0 0 2 2 2 0 CpeS-like protein DUF2207 PF09972.4 ETN98735.1 - 0.21 10.1 1.9 6 5.3 0.1 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) EssA PF10661.4 ETN98736.1 - 0.0053 16.4 4.6 0.0053 16.4 3.2 2.4 2 1 0 2 2 2 1 WXG100 protein secretion system (Wss), protein EssA ADIP PF11559.3 ETN98736.1 - 0.0062 16.4 6.0 0.0062 16.4 4.1 2.2 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding TMF_TATA_bd PF12325.3 ETN98736.1 - 0.0067 16.1 7.3 0.0067 16.1 5.1 2.4 2 1 0 2 2 2 1 TATA element modulatory factor 1 TATA binding Mnd1 PF03962.10 ETN98736.1 - 0.016 14.8 6.3 0.016 14.8 4.4 2.1 2 0 0 2 2 2 0 Mnd1 family HAUS5 PF14817.1 ETN98736.1 - 0.024 13.1 7.3 0.036 12.6 5.1 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Spc24 PF08286.6 ETN98736.1 - 0.054 13.1 15.0 0.09 12.4 1.3 3.1 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 YMF19 PF02326.10 ETN98736.1 - 0.23 12.0 0.2 0.23 12.0 0.2 2.6 1 1 2 3 3 3 0 Plant ATP synthase F0 Myosin_tail_1 PF01576.14 ETN98736.1 - 0.27 8.9 17.5 0.021 12.5 2.3 2.1 2 0 0 2 2 2 0 Myosin tail DUF3573 PF12097.3 ETN98736.1 - 0.43 9.1 3.6 0.98 7.9 2.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) Golgin_A5 PF09787.4 ETN98736.1 - 1.4 7.3 16.9 17 3.7 11.7 2.0 1 1 0 1 1 1 0 Golgin subfamily A member 5 FlxA PF14282.1 ETN98736.1 - 1.5 8.7 23.0 0.15 12.0 8.3 2.9 2 1 0 3 3 3 0 FlxA-like protein DUF1003 PF06210.6 ETN98736.1 - 1.6 8.7 7.1 0.29 11.0 1.6 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1003) Cep57_CLD_2 PF14197.1 ETN98736.1 - 1.8 8.5 14.1 1.5 8.7 0.1 3.4 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 HR1 PF02185.11 ETN98736.1 - 1.8 8.3 22.8 0.16 11.7 6.1 3.3 2 2 1 3 3 3 0 Hr1 repeat DUF3584 PF12128.3 ETN98736.1 - 4.5 4.4 15.9 0.0063 13.9 2.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF948 PF06103.6 ETN98736.1 - 6.8 6.6 9.7 4.5 7.2 0.2 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) GAS PF13851.1 ETN98736.1 - 7.3 5.7 25.2 3.7 6.6 7.5 2.8 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3166 PF11365.3 ETN98736.1 - 7.9 7.0 11.3 13 6.2 1.9 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3166) V_ATPase_I PF01496.14 ETN98736.1 - 9.1 3.9 13.8 47 1.6 9.5 1.8 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2714 PF10896.3 ETN98739.1 - 0.0098 15.7 0.3 0.022 14.5 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2714) XS PF03468.9 ETN98739.1 - 0.018 14.9 0.1 0.032 14.1 0.1 1.4 1 0 0 1 1 1 0 XS domain Ctr PF04145.10 ETN98740.1 - 1.1 9.3 3.9 0.48 10.4 0.4 1.8 2 0 0 2 2 2 0 Ctr copper transporter family Fmp27_SW PF10305.4 ETN98740.1 - 1.6 9.1 9.1 2.3 8.6 0.1 2.3 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain DMAP1 PF05499.7 ETN98740.1 - 5.6 6.4 15.0 0.97 8.9 4.4 2.1 2 0 0 2 2 2 0 DNA methyltransferase 1-associated protein 1 (DMAP1) AAA_11 PF13086.1 ETN98740.1 - 8 5.9 10.7 1.9 7.9 4.9 1.6 1 1 1 2 2 2 0 AAA domain Lipase3_N PF03893.11 ETN98742.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipase 3 N-terminal region TMF_DNA_bd PF12329.3 ETN98743.1 - 0.001 18.8 84.0 0.021 14.5 9.2 5.4 1 1 6 7 7 7 4 TATA element modulatory factor 1 DNA binding CCDC155 PF14662.1 ETN98743.1 - 0.0025 17.4 62.4 0.03 13.9 15.5 2.5 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 Reo_sigmaC PF04582.7 ETN98743.1 - 0.0026 16.9 10.7 0.066 12.3 0.8 2.7 1 1 1 2 2 2 2 Reovirus sigma C capsid protein Seryl_tRNA_N PF02403.17 ETN98743.1 - 0.016 15.1 66.3 0.031 14.2 12.8 3.3 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF16 PF01519.11 ETN98743.1 - 0.038 14.2 69.0 2 8.6 12.1 4.4 1 1 3 4 4 4 0 Protein of unknown function DUF16 APG6 PF04111.7 ETN98743.1 - 0.086 11.8 67.4 0.04 12.9 21.9 2.8 1 1 2 3 3 3 0 Autophagy protein Apg6 DivIC PF04977.10 ETN98743.1 - 0.13 11.7 75.5 0.13 11.7 6.1 6.0 1 1 5 6 6 6 0 Septum formation initiator IncA PF04156.9 ETN98743.1 - 0.17 11.4 62.3 1.8 8.1 22.9 3.1 1 1 2 3 3 3 0 IncA protein HTH_25 PF13413.1 ETN98743.1 - 0.28 10.8 4.1 13 5.5 0.0 3.3 3 1 0 3 3 3 0 Helix-turn-helix domain Filament PF00038.16 ETN98743.1 - 0.52 9.7 56.3 0.68 9.3 5.9 3.2 1 1 2 3 3 3 0 Intermediate filament protein DUF4200 PF13863.1 ETN98743.1 - 0.87 9.5 74.8 0.043 13.7 25.1 3.9 1 1 3 4 4 4 0 Domain of unknown function (DUF4200) GAS PF13851.1 ETN98743.1 - 0.91 8.6 74.8 0.74 8.9 23.7 3.0 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Mod_r PF07200.8 ETN98743.1 - 1 9.2 62.7 0.38 10.6 13.3 4.5 1 1 3 4 4 4 0 Modifier of rudimentary (Mod(r)) protein DUF3584 PF12128.3 ETN98743.1 - 1.9 5.7 52.4 2.7 5.1 36.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MAD PF05557.8 ETN98743.1 - 2 6.3 60.4 1.6 6.7 24.8 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein TPR_MLP1_2 PF07926.7 ETN98743.1 - 2.5 7.8 73.9 0.3 10.8 11.5 4.4 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein zf-C4H2 PF10146.4 ETN98743.1 - 6.7 6.6 56.6 0.33 10.9 20.2 2.1 1 1 1 2 2 2 0 Zinc finger-containing protein DUF3450 PF11932.3 ETN98743.1 - 7.5 5.7 57.4 0.26 10.5 7.0 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.5 ETN98743.1 - 8.3 6.5 55.6 0.18 11.9 16.4 3.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.4 ETN98743.1 - 8.8 6.5 59.5 3.9 7.6 9.1 4.7 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF447 PF04289.7 ETN98743.1 - 9.5 5.7 15.5 5.9 6.4 1.7 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF447) WD40 PF00400.27 ETN98744.1 - 3.3e-07 29.9 8.1 0.037 13.9 0.0 4.6 4 1 0 4 4 4 3 WD domain, G-beta repeat Sec20 PF03908.8 ETN98744.1 - 0.038 13.6 9.5 0.38 10.5 3.4 2.9 2 0 0 2 2 2 0 Sec20 Laminin_II PF06009.7 ETN98744.1 - 9.6 5.9 13.6 3.8 7.2 6.5 2.5 2 1 1 3 3 3 0 Laminin Domain II HSP70 PF00012.15 ETN98745.1 - 0.00025 19.1 0.2 0.0067 14.3 0.5 2.1 1 1 0 2 2 2 2 Hsp70 protein HSP70 PF00012.15 ETN98748.1 - 0.02 12.8 0.0 0.043 11.7 0.0 1.5 1 1 0 1 1 1 0 Hsp70 protein HEAT_2 PF13646.1 ETN98749.1 - 0.0039 17.4 0.4 0.06 13.6 0.1 2.4 2 0 0 2 2 2 1 HEAT repeats WD40 PF00400.27 ETN98750.1 - 1.2e-70 231.0 18.0 2e-13 49.6 0.1 6.0 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETN98750.1 - 1.4e-11 44.5 0.8 1.2e-06 28.4 0.2 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETN98750.1 - 3.9e-10 38.4 7.6 0.0038 15.4 0.0 4.7 1 1 4 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETN98750.1 - 3.3e-07 29.4 6.8 0.05 12.3 0.2 5.0 1 1 3 4 4 4 4 Nup133 N terminal like PQQ_2 PF13360.1 ETN98750.1 - 7.5e-06 25.5 0.4 2.5e-05 23.8 0.1 1.7 1 1 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETN98750.1 - 1e-05 24.0 0.7 0.3 9.3 0.0 3.0 1 1 2 3 3 3 2 Cytochrome D1 heme domain Mid2 PF04478.7 ETN98750.1 - 0.0042 16.5 0.2 1.8 7.9 0.1 2.4 2 0 0 2 2 2 2 Mid2 like cell wall stress sensor DUF1258 PF06869.7 ETN98750.1 - 0.0047 16.0 1.5 0.22 10.5 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1258) DPPIV_N PF00930.16 ETN98750.1 - 0.0056 15.3 0.1 4.2 5.8 0.0 3.5 1 1 3 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Resistin PF06954.6 ETN98750.1 - 0.013 15.7 0.1 27 5.1 0.0 3.4 2 1 1 3 3 3 0 Resistin Nbas_N PF15492.1 ETN98750.1 - 0.042 12.9 0.4 1.8 7.6 0.0 2.4 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal MCM PF00493.18 ETN98751.1 - 5.9e-90 301.4 1.4 7.1e-90 301.1 1.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 ETN98751.1 - 3.7e-07 29.5 0.1 9.6e-05 21.6 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 ETN98751.1 - 0.0097 15.5 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 ETN98751.1 - 0.012 15.8 0.2 0.036 14.2 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 ETN98751.1 - 0.02 14.4 0.1 0.09 12.2 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain TPR_11 PF13414.1 ETN98752.1 - 2.5e-07 30.2 0.2 4.1e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 ETN98752.1 - 5e-05 22.7 0.2 0.00017 21.0 0.1 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETN98752.1 - 0.0021 17.8 0.1 0.0047 16.7 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Pkinase PF00069.20 ETN98753.1 - 8.5e-40 136.5 0.0 1.3e-39 135.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETN98753.1 - 2.3e-15 56.3 0.0 3.8e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETN98753.1 - 3.3e-06 26.2 0.0 4.4e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PEPcase PF00311.12 ETN98753.1 - 0.034 12.0 0.3 0.046 11.5 0.2 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Seadorna_VP7 PF07387.6 ETN98753.1 - 0.081 11.7 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 ETN98753.1 - 0.12 12.0 0.0 2.1 8.0 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family LIF_OSM PF01291.12 ETN98755.1 - 0.02 14.8 0.1 0.045 13.6 0.1 1.5 1 1 0 1 1 1 0 LIF / OSM family SapB_2 PF03489.12 ETN98755.1 - 0.029 14.3 0.1 1.3 9.1 0.0 2.7 2 0 0 2 2 2 0 Saposin-like type B, region 2 Ank_2 PF12796.2 ETN98756.1 - 0.013 15.8 4.8 7.4 6.9 0.0 4.7 4 3 0 4 4 4 0 Ankyrin repeats (3 copies) VIT1 PF01988.14 ETN98757.1 - 1.1e-58 198.2 3.5 1.2e-58 198.0 2.4 1.0 1 0 0 1 1 1 1 VIT family BON PF04972.12 ETN98758.1 - 1.1e-30 105.1 6.0 8.1e-19 67.1 1.2 2.3 2 0 0 2 2 2 2 BON domain DUF3244 PF11589.3 ETN98758.1 - 0.032 13.9 4.2 1.6 8.4 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3244) EFG_C PF00679.19 ETN98758.1 - 0.11 12.4 0.0 8.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Elongation factor G C-terminus RGS PF00615.14 ETN98760.1 - 3.6e-07 30.2 0.5 1.8e-06 28.0 0.0 2.3 2 1 0 2 2 2 1 Regulator of G protein signaling domain DUF842 PF05811.8 ETN98762.1 - 0.29 10.6 7.5 0.12 11.7 1.6 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) DUF241 PF03087.9 ETN98765.1 - 0.02 14.3 1.2 0.025 14.0 0.8 1.1 1 0 0 1 1 1 0 Arabidopsis protein of unknown function Tox-REase-2 PF15646.1 ETN98765.1 - 0.11 12.4 0.3 0.18 11.7 0.2 1.4 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 2 RhoGEF PF00621.15 ETN98765.1 - 0.17 11.7 4.3 0.25 11.1 3.0 1.3 1 1 0 1 1 1 0 RhoGEF domain IncA PF04156.9 ETN98765.1 - 0.25 10.8 2.0 0.27 10.8 1.4 1.1 1 0 0 1 1 1 0 IncA protein Herpes_BLRF2 PF05812.7 ETN98766.1 - 9.1e-05 22.2 3.1 9.1e-05 22.2 2.1 1.8 2 0 0 2 2 2 1 Herpesvirus BLRF2 protein ATG16 PF08614.6 ETN98766.1 - 0.0068 16.2 11.0 0.0083 15.9 7.6 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Cauli_AT PF03233.8 ETN98766.1 - 0.0072 16.0 7.9 0.0086 15.8 5.5 1.2 1 0 0 1 1 1 1 Aphid transmission protein CENP-R PF06729.7 ETN98766.1 - 0.0084 15.7 4.6 0.012 15.2 3.2 1.3 1 0 0 1 1 1 1 Kinetochore component, CENP-R Nup54 PF13874.1 ETN98766.1 - 0.012 15.2 9.6 0.012 15.2 6.4 1.3 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 DivIC PF04977.10 ETN98766.1 - 0.014 14.9 10.4 0.014 14.9 7.2 2.5 1 1 2 3 3 3 0 Septum formation initiator LCD1 PF09798.4 ETN98766.1 - 0.025 12.5 13.0 0.029 12.3 9.0 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein HDV_ag PF01517.13 ETN98766.1 - 0.032 13.9 3.6 0.041 13.5 2.5 1.2 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen ADIP PF11559.3 ETN98766.1 - 0.032 14.1 16.0 0.041 13.7 11.1 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF1465 PF07323.7 ETN98766.1 - 0.037 13.5 3.7 0.045 13.3 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) AAA_13 PF13166.1 ETN98766.1 - 0.043 12.2 13.8 0.047 12.1 9.5 1.0 1 0 0 1 1 1 0 AAA domain CR6_interact PF10147.4 ETN98766.1 - 0.045 13.0 13.3 0.051 12.8 9.2 1.1 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Prominin PF05478.6 ETN98766.1 - 0.049 11.1 5.7 0.053 11.0 4.0 1.0 1 0 0 1 1 1 0 Prominin DUF3405 PF11885.3 ETN98766.1 - 0.052 11.7 4.9 0.054 11.7 3.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) DUF3373 PF11853.3 ETN98766.1 - 0.057 11.9 6.3 0.058 11.9 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) UPF0184 PF03670.8 ETN98766.1 - 0.062 13.4 2.3 0.096 12.8 1.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Sigma70_ner PF04546.8 ETN98766.1 - 0.066 12.8 10.9 0.086 12.4 7.5 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region ASD2 PF08687.6 ETN98766.1 - 0.067 12.5 9.7 0.075 12.3 6.7 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 HAUS5 PF14817.1 ETN98766.1 - 0.098 11.1 10.1 0.12 10.9 7.0 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 IncA PF04156.9 ETN98766.1 - 0.1 12.1 13.7 0.12 11.9 9.5 1.2 1 0 0 1 1 1 0 IncA protein CENP-Q PF13094.1 ETN98766.1 - 0.12 12.4 16.4 0.087 12.8 10.4 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit APG6 PF04111.7 ETN98766.1 - 0.13 11.2 16.5 0.14 11.1 11.4 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DOR PF14839.1 ETN98766.1 - 0.15 11.8 8.7 0.18 11.5 6.1 1.1 1 0 0 1 1 1 0 DOR family Fzo_mitofusin PF04799.8 ETN98766.1 - 0.15 11.4 6.4 0.21 10.9 4.4 1.4 1 0 0 1 1 1 0 fzo-like conserved region BBS2_C PF14782.1 ETN98766.1 - 0.17 10.3 8.0 0.21 10.1 5.6 1.0 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal DUF2730 PF10805.3 ETN98766.1 - 0.18 11.5 5.0 0.24 11.1 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF4355 PF14265.1 ETN98766.1 - 0.19 11.7 16.1 0.24 11.3 11.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Atg14 PF10186.4 ETN98766.1 - 0.23 10.3 11.9 0.26 10.1 8.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 ETN98766.1 - 0.24 10.0 13.9 0.27 9.8 9.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2205 PF10224.4 ETN98766.1 - 0.24 10.9 11.6 0.62 9.6 7.8 1.8 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF489 PF04356.7 ETN98766.1 - 0.26 10.8 4.3 0.31 10.5 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF489) Glyco_tran_28_C PF04101.11 ETN98766.1 - 0.28 10.8 7.0 0.38 10.3 4.9 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Fmp27_WPPW PF10359.4 ETN98766.1 - 0.29 9.5 11.5 0.32 9.3 8.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Allexi_40kDa PF05549.6 ETN98766.1 - 0.37 10.0 4.6 0.4 9.9 3.2 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF342 PF03961.8 ETN98766.1 - 0.43 8.9 11.9 0.48 8.7 8.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CCDC66 PF15236.1 ETN98766.1 - 0.44 10.1 19.7 0.58 9.7 13.7 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 DUF607 PF04678.8 ETN98766.1 - 0.49 10.3 4.7 0.62 9.9 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF607 TMCO5 PF14992.1 ETN98766.1 - 0.5 9.4 15.0 0.54 9.3 10.4 1.1 1 0 0 1 1 1 0 TMCO5 family DUF2400 PF09674.5 ETN98766.1 - 0.67 9.5 4.6 0.77 9.4 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) V_ATPase_I PF01496.14 ETN98766.1 - 0.73 7.6 9.1 0.77 7.5 6.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATHILA PF03078.10 ETN98766.1 - 0.79 8.2 10.0 1 7.8 6.9 1.1 1 0 0 1 1 1 0 ATHILA ORF-1 family DUF1192 PF06698.6 ETN98766.1 - 0.87 9.4 4.8 2.3 8.0 3.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) UPF0449 PF15136.1 ETN98766.1 - 0.96 9.7 8.4 1.4 9.1 5.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 AAA_11 PF13086.1 ETN98766.1 - 1.1 8.8 10.3 1.3 8.5 7.1 1.1 1 0 0 1 1 1 0 AAA domain FliD_N PF02465.13 ETN98766.1 - 1.1 9.6 6.1 1.4 9.2 4.2 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Snf7 PF03357.16 ETN98766.1 - 1.2 8.4 17.6 0.027 13.8 7.1 1.8 1 1 1 2 2 2 0 Snf7 OmpH PF03938.9 ETN98766.1 - 1.3 8.9 15.8 1.8 8.4 10.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) GrpE PF01025.14 ETN98766.1 - 1.3 8.4 12.5 1.8 8.0 8.7 1.3 1 0 0 1 1 1 0 GrpE SlyX PF04102.7 ETN98766.1 - 1.4 9.3 11.2 0.12 12.8 3.6 2.1 2 1 1 3 3 2 0 SlyX Uds1 PF15456.1 ETN98766.1 - 1.8 8.5 14.1 1.3 8.9 8.2 1.8 1 1 1 2 2 2 0 Up-regulated During Septation TMEM192 PF14802.1 ETN98766.1 - 1.8 7.3 6.0 2.4 6.9 4.2 1.2 1 0 0 1 1 1 0 TMEM192 family DUF4175 PF13779.1 ETN98766.1 - 1.8 6.1 10.5 2.2 5.9 7.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PA26 PF04636.8 ETN98766.1 - 2 7.0 10.8 2.3 6.8 7.5 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) TMF_DNA_bd PF12329.3 ETN98766.1 - 2.7 7.8 19.9 4.7 7.0 13.0 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding HemX PF04375.9 ETN98766.1 - 2.9 6.3 10.2 3.3 6.2 7.1 1.1 1 0 0 1 1 1 0 HemX DUF3573 PF12097.3 ETN98766.1 - 3.3 6.2 5.7 3.4 6.1 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) TMPIT PF07851.8 ETN98766.1 - 3.9 6.4 10.1 4.3 6.3 7.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein Med19 PF10278.4 ETN98766.1 - 4.1 7.0 12.1 5.2 6.6 8.4 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 ALMT PF11744.3 ETN98766.1 - 4.7 5.7 6.4 5.5 5.5 4.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Exonuc_VII_L PF02601.10 ETN98766.1 - 5.1 6.1 12.3 5.8 6.0 8.5 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit SID-1_RNA_chan PF13965.1 ETN98766.1 - 5.4 5.0 7.1 5.6 5.0 4.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4140 PF13600.1 ETN98766.1 - 6.2 7.3 8.7 14 6.1 6.0 1.8 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF1049 PF06305.6 ETN98766.1 - 6.3 6.3 6.3 2.7 7.5 1.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1049) DUF2802 PF10975.3 ETN98766.1 - 6.9 6.5 11.6 0.2 11.4 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2802) DUF4446 PF14584.1 ETN98766.1 - 7.2 6.4 11.5 4 7.2 6.6 1.7 1 1 1 2 2 1 0 Protein of unknown function (DUF4446) WD40 PF00400.27 ETN98768.1 - 1.1e-56 186.8 2.0 9.7e-13 47.4 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 ETN98768.1 - 2.6e-09 37.0 0.9 0.0012 18.6 0.1 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETN98768.1 - 5.1e-09 34.9 0.0 9.3e-05 20.8 0.0 2.6 2 1 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.7 ETN98768.1 - 9e-05 22.0 9.1 0.62 9.7 0.0 6.0 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.9 ETN98768.1 - 0.00051 18.9 1.3 0.0093 14.8 0.1 2.0 1 1 1 2 2 2 1 Coatomer WD associated region Nup160 PF11715.3 ETN98768.1 - 0.0021 16.3 0.1 0.72 7.9 0.0 3.8 1 1 0 2 2 2 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETN98768.1 - 0.0036 16.1 8.1 0.11 11.2 1.3 4.1 1 1 2 4 4 4 1 Nup133 N terminal like Str_synth PF03088.11 ETN98768.1 - 0.0062 16.5 0.0 13 5.9 0.0 4.2 4 1 1 5 5 5 0 Strictosidine synthase PQQ_2 PF13360.1 ETN98768.1 - 0.0075 15.7 0.0 0.18 11.2 0.0 2.2 1 1 1 2 2 2 1 PQQ-like domain Gmad1 PF10647.4 ETN98768.1 - 0.064 12.6 0.0 0.8 9.0 0.0 2.6 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain Resistin PF06954.6 ETN98768.1 - 0.066 13.5 0.1 43 4.4 0.0 3.3 2 1 1 3 3 3 0 Resistin Proteasome_A_N PF10584.4 ETN98768.1 - 0.14 11.5 1.7 37 3.7 0.0 3.8 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 ETN98769.1 - 1e-75 247.1 14.0 1.3e-14 53.3 0.1 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat PQQ_2 PF13360.1 ETN98769.1 - 7.5e-15 55.0 3.0 7.5e-09 35.4 0.2 2.9 1 1 2 3 3 3 3 PQQ-like domain eIF2A PF08662.6 ETN98769.1 - 2.1e-14 53.6 0.0 1.9e-05 24.4 0.0 3.0 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.4 ETN98769.1 - 7e-09 35.4 0.3 0.0019 17.6 0.0 3.3 1 1 1 3 3 3 3 Lipoprotein LpqB beta-propeller domain PD40 PF07676.7 ETN98769.1 - 1.3e-06 27.9 9.3 7.3 6.3 0.1 5.4 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETN98769.1 - 1.4e-06 26.8 1.4 0.14 10.4 0.0 3.4 1 1 3 4 4 4 4 Cytochrome D1 heme domain DUF1652 PF07865.6 ETN98769.1 - 2.3e-06 27.0 0.0 1.1 8.9 0.0 5.3 2 2 4 6 6 6 1 Protein of unknown function (DUF1652) DUF4072 PF13284.1 ETN98769.1 - 0.00012 22.1 0.0 12 6.1 0.0 5.5 6 0 0 6 6 6 0 Domain of unknown function (DUF4072) PQQ PF01011.16 ETN98769.1 - 0.00014 21.1 0.0 4.2 7.0 0.0 5.0 6 0 0 6 6 6 1 PQQ enzyme repeat Proteasome_A_N PF10584.4 ETN98769.1 - 0.00085 18.5 10.0 23 4.4 0.0 6.0 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature DUF3312 PF11768.3 ETN98769.1 - 0.0018 16.5 0.0 0.92 7.6 0.0 3.3 1 1 3 4 4 4 2 Protein of unknown function (DUF3312) DUF1258 PF06869.7 ETN98769.1 - 0.002 17.2 0.1 0.89 8.5 0.0 3.1 2 1 1 3 3 3 1 Protein of unknown function (DUF1258) NYD-SP28_assoc PF14775.1 ETN98769.1 - 0.0048 16.5 0.1 10 5.8 0.0 4.5 5 0 0 5 5 5 0 Sperm tail C-terminal domain TolB_N PF04052.8 ETN98769.1 - 0.0055 16.7 0.0 27 4.8 0.0 4.9 6 0 0 6 6 6 0 TolB amino-terminal domain DUF3509 PF12021.3 ETN98769.1 - 0.012 15.3 0.1 0.41 10.4 0.0 3.1 3 2 1 4 4 4 0 Protein of unknown function (DUF3509) PLD_C PF12357.3 ETN98769.1 - 0.15 11.5 0.3 1.1e+02 2.4 0.0 4.0 1 1 5 6 6 6 0 Phospholipase D C terminal Kelch_2 PF07646.10 ETN98772.1 - 4.4e-07 29.4 0.7 6.4e-05 22.5 0.3 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETN98772.1 - 1.4e-06 28.2 0.8 0.00098 19.2 0.2 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.20 ETN98772.1 - 1.3e-05 24.6 6.0 0.0007 19.0 0.8 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 ETN98772.1 - 9.1e-05 22.1 0.3 0.38 10.5 0.0 2.6 2 1 0 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETN98772.1 - 0.00016 21.7 0.9 0.033 14.3 0.0 2.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETN98772.1 - 0.012 15.6 3.4 0.41 10.6 0.0 2.7 2 1 0 2 2 2 0 Kelch motif Bacteriocin_IIi PF11758.3 ETN98773.1 - 0.037 13.6 0.5 0.29 10.7 0.1 2.3 2 0 0 2 2 2 0 Aureocin-like type II bacteriocin YrpD PF15493.1 ETN98773.1 - 0.07 12.7 2.2 0.088 12.4 1.5 1.4 1 1 0 1 1 1 0 Domain of unknown function, YrpD CNPase PF05881.7 ETN98774.1 - 0.067 12.5 0.0 0.074 12.4 0.0 1.2 1 0 0 1 1 1 0 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) SDP_N PF12278.3 ETN98775.1 - 0.023 14.3 2.1 0.036 13.6 1.5 1.3 1 0 0 1 1 1 0 Sex determination protein N terminal Macoilin PF09726.4 ETN98775.1 - 0.089 11.0 6.2 0.095 10.9 4.3 1.0 1 0 0 1 1 1 0 Transmembrane protein Secretin_N_2 PF07655.8 ETN98775.1 - 1 9.8 22.2 0.67 10.3 14.1 1.6 2 0 0 2 2 2 0 Secretin N-terminal domain Pex14_N PF04695.8 ETN98775.1 - 2 8.4 9.0 2.7 8.0 6.2 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4114 PF13448.1 ETN98775.1 - 2.8 8.8 10.1 2 9.3 5.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4114) DUF1117 PF06547.7 ETN98775.1 - 4.4 7.4 6.9 8.2 6.5 4.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1117) DIL PF01843.14 ETN98776.1 - 0.047 13.5 0.7 0.072 12.9 0.5 1.3 1 0 0 1 1 1 0 DIL domain DUF4163 PF13739.1 ETN98777.1 - 0.23 12.2 1.7 0.34 11.7 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4163) AAT PF03417.11 ETN98778.1 - 0.1 12.0 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase DDE_Tnp_IS240 PF13610.1 ETN98778.1 - 0.43 10.5 5.6 2.6 8.0 0.1 2.7 1 1 0 3 3 3 0 DDE domain BBS2_C PF14782.1 ETN98779.1 - 0.023 13.2 0.5 0.023 13.2 0.4 1.0 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Zot PF05707.7 ETN98779.1 - 0.046 13.1 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) Rho_Binding PF08912.6 ETN98779.1 - 0.067 13.5 1.9 0.1 12.9 1.3 1.3 1 0 0 1 1 1 0 Rho Binding MMS19_N PF14500.1 ETN98780.1 - 0.023 13.9 6.9 0.024 13.9 3.8 1.7 1 1 1 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II Glyco_transf_41 PF13844.1 ETN98780.1 - 0.034 12.1 5.0 0.04 11.8 3.4 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 41 DUF310 PF03750.8 ETN98780.1 - 0.044 13.9 1.4 0.044 13.9 1.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF310) BBP1_C PF15272.1 ETN98780.1 - 0.28 10.7 20.6 0.3 10.6 13.7 1.6 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal PID PF00640.18 ETN98780.1 - 0.3 11.0 7.1 0.57 10.1 4.8 1.7 1 1 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) Sigma70_ECF PF07638.6 ETN98780.1 - 0.37 10.4 4.8 0.4 10.3 1.5 2.2 2 1 1 3 3 3 0 ECF sigma factor HSD3 PF15244.1 ETN98780.1 - 0.42 9.8 14.2 0.63 9.2 9.8 1.4 1 0 0 1 1 1 0 Hydroxy-steroid dehydrogenase DUF2316 PF10078.4 ETN98780.1 - 1.9 8.5 8.9 0.22 11.5 2.3 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) Neugrin PF06413.6 ETN98780.1 - 2.8 7.6 16.8 2.9 7.6 4.4 2.1 1 1 1 2 2 2 0 Neugrin DUF4071 PF13281.1 ETN98780.1 - 3.3 6.4 12.8 0.14 10.9 3.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4071) ACCA PF03255.9 ETN98780.1 - 3.6 7.1 7.5 2.8 7.5 3.5 1.9 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Sds3 PF08598.6 ETN98780.1 - 5.5 6.4 20.7 8.3 5.8 14.4 1.3 1 1 0 1 1 1 0 Sds3-like ADIP PF11559.3 ETN98780.1 - 6.3 6.6 23.4 0.35 10.7 5.8 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Phage_GP20 PF06810.6 ETN98780.1 - 6.8 6.1 21.0 0.35 10.2 5.6 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 HEAT_2 PF13646.1 ETN98781.1 - 7.8e-05 22.8 0.0 0.022 14.9 0.0 2.6 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.17 ETN98781.1 - 0.0072 16.3 0.0 8.4 6.7 0.0 4.2 4 0 0 4 4 4 1 HEAT repeat CLASP_N PF12348.3 ETN98781.1 - 0.037 13.3 0.2 0.079 12.3 0.0 1.7 2 0 0 2 2 2 0 CLASP N terminal Cnd1 PF12717.2 ETN98781.1 - 0.12 12.1 4.2 2.6 7.8 0.4 2.8 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 FPL PF09758.4 ETN98781.1 - 0.15 11.8 3.0 8.9 6.0 0.1 3.0 3 0 0 3 3 3 0 Uncharacterised conserved protein Imm16 PF15565.1 ETN98781.1 - 0.4 10.5 2.2 8.3 6.3 0.1 3.1 3 1 0 3 3 3 0 Immunity protein 16 CagY_M PF07337.6 ETN98781.1 - 7.6 6.1 8.6 0.7 9.4 0.1 3.1 3 0 0 3 3 3 0 DC-EC Repeat AAA PF00004.24 ETN98782.1 - 0.007 16.5 0.1 0.044 13.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETN98782.1 - 0.029 14.4 0.0 0.24 11.5 0.0 2.4 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 ETN98782.1 - 0.038 13.7 0.0 0.088 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Integrase_Zn PF02022.14 ETN98782.1 - 0.06 12.7 0.1 0.16 11.3 0.1 1.8 1 0 0 1 1 1 0 Integrase Zinc binding domain Cir_Bir_Yir PF06022.6 ETN98783.1 - 0.0047 16.1 0.7 0.0061 15.8 0.5 1.1 1 0 0 1 1 1 1 Plasmodium variant antigen protein Cir/Yir/Bir VWA PF00092.23 ETN98784.1 - 3.2e-05 23.7 0.1 4.6e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Cu2_monooxygen PF01082.15 ETN98785.1 - 0.0037 17.2 0.4 0.0051 16.7 0.3 1.2 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Peptidase_C41 PF05417.6 ETN98785.1 - 0.08 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Hepatitis E cysteine protease DUF1672 PF07901.6 ETN98786.1 - 0.013 14.5 1.5 0.015 14.2 1.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) Peptidase_C41 PF05417.6 ETN98786.1 - 0.021 14.3 0.0 0.023 14.2 0.0 1.1 1 0 0 1 1 1 0 Hepatitis E cysteine protease Kelch_5 PF13854.1 ETN98787.1 - 0.0033 17.3 0.2 0.093 12.7 0.2 2.6 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.20 ETN98787.1 - 0.0035 16.8 4.3 0.0059 16.1 0.3 2.9 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 ETN98787.1 - 0.015 15.4 0.0 0.053 13.7 0.0 2.0 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_6 PF13964.1 ETN98787.1 - 0.015 15.4 1.5 0.076 13.2 0.3 2.5 2 0 0 2 2 2 0 Kelch motif Kelch_4 PF13418.1 ETN98787.1 - 0.029 14.1 0.2 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_2 PF07646.10 ETN98787.1 - 0.13 12.1 1.5 0.71 9.7 0.1 2.7 3 1 0 3 3 3 0 Kelch motif ORC5_C PF14630.1 ETN98788.1 - 8.4 5.7 13.8 13 5.1 9.5 1.4 1 1 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus Otopetrin PF03189.8 ETN98788.1 - 9.8 5.0 12.2 10 4.9 8.1 1.3 1 1 0 1 1 1 0 Otopetrin DUF3294 PF07957.6 ETN98789.1 - 0.023 14.2 1.4 0.032 13.7 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) Guanylate_cyc PF00211.15 ETN98790.1 - 9.4e-08 31.6 0.1 1.3e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.15 ETN98791.1 - 4.3e-26 91.3 0.9 1.5e-25 89.6 0.6 1.9 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain NOA36 PF06524.7 ETN98793.1 - 0.0029 16.9 2.4 0.0035 16.6 1.7 1.2 1 0 0 1 1 1 1 NOA36 protein TPR_12 PF13424.1 ETN98794.1 - 3.5e-16 58.9 7.8 7.9e-09 35.3 0.3 2.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETN98794.1 - 1.7e-08 33.9 10.0 5.6e-06 25.9 0.8 2.2 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 ETN98794.1 - 4.7e-08 32.3 5.0 8e-05 22.2 0.2 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETN98794.1 - 6.1e-07 28.7 3.5 0.0021 17.7 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETN98794.1 - 7.6e-07 28.4 4.8 7.6e-06 25.3 0.4 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETN98794.1 - 4.6e-06 26.0 0.6 4.7e-05 22.8 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETN98794.1 - 7.3e-06 25.7 0.0 9.1e-05 22.2 0.0 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_3 PF07720.7 ETN98794.1 - 0.0075 16.0 0.5 0.021 14.6 0.3 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETN98794.1 - 0.01 16.4 0.0 3 8.7 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETN98794.1 - 0.017 15.3 0.2 0.29 11.4 0.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF627 PF04781.7 ETN98794.1 - 0.082 12.5 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF627) ubiquitin PF00240.18 ETN98795.1 - 9.8e-16 56.9 4.3 2.2e-15 55.7 0.1 2.5 3 0 0 3 3 3 1 Ubiquitin family Rad60-SLD PF11976.3 ETN98795.1 - 7.3e-08 31.9 0.1 1.5e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Internalin_N PF12354.3 ETN98795.1 - 0.16 11.6 1.7 2.3 7.9 0.2 2.2 2 0 0 2 2 2 0 Bacterial adhesion/invasion protein N terminal ART PF01129.13 ETN98796.1 - 0.043 12.9 0.0 0.079 12.0 0.0 1.4 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase Tubulin PF00091.20 ETN98797.1 - 9.8e-07 28.8 0.1 1.5e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Peptidase_M15_3 PF08291.6 ETN98799.1 - 0.057 13.2 0.2 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Peptidase M15 PPP4R2 PF09184.6 ETN98800.1 - 0.72 9.3 11.8 1.4 8.3 8.2 1.4 1 0 0 1 1 1 0 PPP4R2 Hid1 PF12722.2 ETN98800.1 - 6.1 4.3 10.8 7.6 4.0 7.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PMSR PF01625.16 ETN98803.1 - 0.0063 16.3 0.8 0.0098 15.7 0.5 1.4 1 1 0 1 1 1 1 Peptide methionine sulfoxide reductase MiAMP1 PF09117.5 ETN98803.1 - 0.1 13.0 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 MiAMP1 zf-RING_2 PF13639.1 ETN98806.1 - 0.00037 20.2 0.1 0.12 12.2 0.0 2.2 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.1 ETN98806.1 - 0.0055 16.7 1.5 0.16 12.0 0.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-met PF12874.2 ETN98806.1 - 0.013 15.7 1.4 0.028 14.6 1.0 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-RING_4 PF14570.1 ETN98806.1 - 0.022 14.3 1.6 2.2 7.9 0.1 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain TruD PF01142.13 ETN98806.1 - 0.038 12.6 0.1 0.04 12.5 0.1 1.1 1 0 0 1 1 1 0 tRNA pseudouridine synthase D (TruD) zf-rbx1 PF12678.2 ETN98806.1 - 0.046 13.8 0.1 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 ETN98806.1 - 0.062 12.9 0.9 2.9 7.6 0.1 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 ETN98806.1 - 0.27 10.7 2.2 2.9 7.4 1.4 2.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Dna2 PF08696.6 ETN98807.1 - 1.7e-12 47.1 4.4 4e-06 26.3 0.8 3.1 1 1 1 2 2 2 2 DNA replication factor Dna2 DUF1759 PF03564.10 ETN98808.1 - 0.23 11.2 4.1 0.31 10.8 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) TFIID-31kDa PF02291.10 ETN98809.1 - 0.089 12.5 0.3 0.11 12.3 0.2 1.0 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit LssY_C PF14067.1 ETN98810.1 - 0.0076 15.2 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 LssY C-terminus Baculo_IE-1 PF05290.6 ETN98810.1 - 0.078 12.7 0.3 0.078 12.7 0.2 1.7 2 1 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Kelch_6 PF13964.1 ETN98811.1 - 0.00036 20.5 4.0 0.54 10.5 0.0 4.7 4 1 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 ETN98811.1 - 0.0035 16.8 0.2 8.4 6.0 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETN98811.1 - 0.023 14.4 0.5 0.83 9.4 0.0 3.3 3 0 0 3 3 3 0 Galactose oxidase, central domain DUF1796 PF08795.5 ETN98811.1 - 0.038 13.6 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) DUF2415 PF10313.4 ETN98811.1 - 0.062 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) Kelch_2 PF07646.10 ETN98811.1 - 0.083 12.6 0.3 8.8 6.2 0.0 3.5 3 1 0 3 3 3 0 Kelch motif DUF726 PF05277.7 ETN98814.1 - 4.3e-08 32.4 0.0 4.8e-08 32.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF1510 PF07423.6 ETN98814.1 - 0.11 11.9 12.6 0.11 11.8 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Tom37_C PF11801.3 ETN98814.1 - 0.33 10.7 1.6 0.41 10.4 1.1 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain Sporozoite_P67 PF05642.6 ETN98814.1 - 0.55 8.0 3.7 0.46 8.2 2.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RRN3 PF05327.6 ETN98814.1 - 1.3 7.0 8.4 1.3 7.0 5.8 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.9 ETN98814.1 - 2 6.3 13.8 2 6.3 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Rhabdo_ncap PF00945.13 ETN98814.1 - 5.7 5.4 9.3 6.9 5.1 6.4 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein WD40 PF00400.27 ETN98815.1 - 3.2e-05 23.6 1.2 1.7 8.6 0.2 4.7 3 1 0 3 3 3 1 WD domain, G-beta repeat eIF2A PF08662.6 ETN98815.1 - 0.00011 22.0 0.1 0.001 18.8 0.0 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 ETN98815.1 - 0.00039 19.6 0.0 0.094 11.7 0.0 2.2 1 1 1 2 2 2 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 ETN98815.1 - 0.00098 18.7 0.4 4.2 7.1 0.0 3.6 3 1 0 3 3 3 2 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.9 ETN98815.1 - 0.0025 16.7 0.1 0.068 11.9 0.0 2.0 1 1 1 2 2 2 2 Coatomer WD associated region Proteasome_A_N PF10584.4 ETN98815.1 - 0.0087 15.3 0.6 1 8.7 0.0 3.3 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature DPPIV_N PF00930.16 ETN98815.1 - 0.012 14.2 0.0 0.24 9.9 0.0 2.2 1 1 2 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Mid2 PF04478.7 ETN98815.1 - 0.095 12.1 0.2 13 5.2 0.0 2.5 1 1 1 2 2 2 0 Mid2 like cell wall stress sensor Nucleoporin_N PF08801.6 ETN98815.1 - 0.11 11.1 0.2 2.1 7.0 0.2 2.5 1 1 0 1 1 1 0 Nup133 N terminal like Myb_DNA-bind_6 PF13921.1 ETN98817.1 - 0.95 9.6 4.5 0.76 9.9 2.5 1.5 1 1 0 1 1 1 0 Myb-like DNA-binding domain Spt5_N PF11942.3 ETN98817.1 - 4.3 8.0 17.0 5.2 7.7 11.8 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal ERAP1_C PF11838.3 ETN98818.1 - 7.7e-06 25.3 0.0 7.9e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Folate_carrier PF01770.13 ETN98819.1 - 0.014 13.9 0.4 0.021 13.3 0.3 1.1 1 0 0 1 1 1 0 Reduced folate carrier Peptidase_C37 PF05416.7 ETN98819.1 - 0.026 12.8 1.8 0.037 12.3 1.3 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Lectin_C PF00059.16 ETN98819.1 - 0.056 14.0 0.5 0.12 13.0 0.4 1.5 1 0 0 1 1 1 0 Lectin C-type domain DUF2868 PF11067.3 ETN98819.1 - 0.099 11.7 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) WD40 PF00400.27 ETN98821.1 - 7.7e-15 54.1 0.5 1.3e-08 34.4 0.1 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETN98821.1 - 6.7e-05 21.2 0.0 0.13 10.3 0.0 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 FGGY_C PF02782.11 ETN98822.1 - 0.013 15.0 0.1 0.018 14.6 0.1 1.2 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain FlxA PF14282.1 ETN98824.1 - 0.14 12.1 10.4 0.45 10.4 7.2 2.0 1 1 0 1 1 1 0 FlxA-like protein Herpes_capsid PF06112.6 ETN98824.1 - 3.6 7.6 10.0 6.2 6.8 7.0 1.4 1 1 0 1 1 1 0 Gammaherpesvirus capsid protein WD40 PF00400.27 ETN98826.1 - 6.4e-18 63.8 2.8 1.1e-09 37.8 0.2 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETN98826.1 - 0.061 12.0 0.3 0.11 11.2 0.2 1.3 1 1 0 1 1 1 0 Nup133 N terminal like EBA-175_VI PF11556.3 ETN98826.1 - 5.4 7.1 10.2 10 6.3 0.2 2.5 2 1 0 2 2 2 0 Erythrocyte binding antigen 175 HEAT PF02985.17 ETN98827.1 - 0.058 13.4 0.0 0.099 12.7 0.0 1.4 1 0 0 1 1 1 0 HEAT repeat Acid_phosphat_B PF03767.9 ETN98827.1 - 0.062 12.6 0.2 0.062 12.6 0.1 1.1 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) DUF685 PF05085.7 ETN98828.1 - 0.017 14.2 0.1 0.02 13.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF685) TT_ORF1 PF02956.9 ETN98828.1 - 0.055 11.9 4.7 0.055 11.9 3.3 1.0 1 0 0 1 1 1 0 TT viral orf 1 PBP1_TM PF14812.1 ETN98828.1 - 0.082 13.2 2.3 0.1 12.9 1.6 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PRP1_N PF06424.7 ETN98828.1 - 0.34 11.2 4.5 0.42 10.9 3.1 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Phlebovirus_NSM PF07246.6 ETN98828.1 - 0.64 9.1 4.6 0.72 8.9 3.2 1.0 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Kelch_6 PF13964.1 ETN98829.1 - 9.2e-06 25.6 0.7 0.0014 18.6 0.1 2.8 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETN98829.1 - 1.6e-05 24.5 0.1 0.018 14.8 0.0 2.4 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETN98829.1 - 0.0015 18.0 1.1 0.0065 15.9 0.2 2.3 2 0 0 2 2 2 1 Kelch motif eRF1_3 PF03465.10 ETN98830.1 - 7.1e-19 68.1 0.2 1.2e-18 67.4 0.0 1.4 2 0 0 2 2 2 1 eRF1 domain 3 Ribosomal_L7Ae PF01248.21 ETN98830.1 - 0.089 12.3 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Vpu PF00558.14 ETN98832.1 - 0.72 9.4 5.7 2.1 7.9 4.0 1.9 1 0 0 1 1 1 0 Vpu protein Med3 PF11593.3 ETN98832.1 - 0.83 8.8 39.7 1.3 8.1 27.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Peptidase_C14 PF00656.17 ETN98833.1 - 0.00012 21.8 0.3 0.00062 19.5 0.2 1.9 1 1 0 1 1 1 1 Caspase domain Abhydrolase_2 PF02230.11 ETN98833.1 - 0.11 11.9 0.4 0.21 11.0 0.0 1.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase HEAT_2 PF13646.1 ETN98834.1 - 3.9e-50 168.0 24.9 6.6e-15 55.1 0.8 6.3 3 1 2 6 6 5 5 HEAT repeats HEAT PF02985.17 ETN98834.1 - 5.8e-32 106.8 13.7 0.0046 16.9 0.0 12.6 12 0 0 12 12 12 8 HEAT repeat HEAT_EZ PF13513.1 ETN98834.1 - 1.7e-18 66.4 25.2 0.0011 19.3 0.1 9.9 5 4 5 10 10 10 5 HEAT-like repeat Adaptin_N PF01602.15 ETN98834.1 - 5e-17 61.4 8.7 2.3e-11 42.7 0.3 3.3 2 1 1 3 3 3 3 Adaptin N terminal region Ank_4 PF13637.1 ETN98834.1 - 4.3e-12 46.2 0.1 1.5e-08 34.8 0.1 3.6 2 1 1 3 3 2 2 Ankyrin repeats (many copies) Cnd1 PF12717.2 ETN98834.1 - 1.7e-11 44.3 13.2 0.021 14.7 0.2 7.2 4 2 2 7 7 7 4 non-SMC mitotic condensation complex subunit 1 Ank_2 PF12796.2 ETN98834.1 - 6.4e-11 42.4 1.0 7.5e-10 39.0 0.1 3.4 3 1 0 3 3 2 1 Ankyrin repeats (3 copies) DUF294 PF03445.8 ETN98834.1 - 2.9e-10 39.8 2.6 4.6e-07 29.5 0.0 4.8 6 0 0 6 6 6 1 Putative nucleotidyltransferase DUF294 Ank_5 PF13857.1 ETN98834.1 - 1e-08 35.0 2.2 9.1e-08 32.1 0.1 3.3 2 1 1 3 3 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETN98834.1 - 9.1e-08 31.6 0.1 8.9e-05 22.3 0.0 4.4 4 0 0 4 4 3 1 Ankyrin repeat Ank PF00023.25 ETN98834.1 - 1.1e-05 24.9 0.2 0.0002 21.0 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat DUF3385 PF11865.3 ETN98834.1 - 1.6e-05 24.8 10.1 2.6 7.9 0.0 6.9 5 2 2 7 7 7 2 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.2 ETN98834.1 - 0.00017 21.8 0.1 2.4 8.5 0.0 5.9 3 2 3 6 6 6 1 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.11 ETN98834.1 - 0.00041 20.5 25.6 7 7.4 0.1 10.4 11 0 0 11 11 10 2 PBS lyase HEAT-like repeat NTP_transf_2 PF01909.18 ETN98834.1 - 0.15 12.3 0.0 0.48 10.7 0.0 1.9 1 0 0 1 1 1 0 Nucleotidyltransferase domain Methyltrn_RNA_4 PF09936.4 ETN98835.1 - 0.045 13.2 0.0 0.056 12.9 0.0 1.1 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase Pkinase PF00069.20 ETN98835.1 - 0.086 11.9 0.7 0.12 11.5 0.5 1.2 1 0 0 1 1 1 0 Protein kinase domain Peptidase_C14 PF00656.17 ETN98836.1 - 0.00033 20.4 0.1 0.00063 19.5 0.1 1.4 1 0 0 1 1 1 1 Caspase domain DUF1077 PF06417.7 ETN98836.1 - 0.033 13.5 0.1 0.46 9.8 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1077) Endotoxin_M PF00555.14 ETN98836.1 - 0.17 11.6 3.7 1.9 8.2 0.6 2.2 2 0 0 2 2 2 0 delta endotoxin Kelch_1 PF01344.20 ETN98837.1 - 2.7e-09 36.4 1.8 0.00022 20.7 0.1 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETN98837.1 - 2.2e-07 30.7 0.1 0.0019 18.3 0.1 2.7 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.10 ETN98837.1 - 1.4e-05 24.6 0.6 0.013 15.2 0.1 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETN98837.1 - 0.0035 17.0 0.1 1.8 8.3 0.0 2.8 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETN98837.1 - 0.009 15.9 0.1 3.7 7.6 0.0 2.6 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 ETN98837.1 - 0.013 15.7 0.0 1.9 8.7 0.0 3.0 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_6 PF13964.1 ETN98839.1 - 3.5e-05 23.7 4.6 0.79 10.0 0.0 4.4 4 1 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 ETN98839.1 - 0.0019 17.6 5.3 2.3 7.8 0.0 4.0 4 1 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 ETN98839.1 - 0.011 15.5 0.2 0.56 10.0 0.0 3.4 4 0 0 4 4 4 0 Galactose oxidase, central domain CLASP_N PF12348.3 ETN98839.1 - 0.13 11.6 0.2 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 CLASP N terminal Kinesin PF00225.18 ETN98840.1 - 3.6e-27 94.9 0.0 4.8e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain DUF4043 PF13252.1 ETN98840.1 - 0.072 12.0 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4043) MMR_HSR1 PF01926.18 ETN98841.1 - 2.2e-06 27.6 0.0 4.6e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 ETN98841.1 - 0.00012 21.3 0.1 0.00033 19.8 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 ETN98841.1 - 0.00091 19.5 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Miro PF08477.8 ETN98841.1 - 0.0014 19.0 0.0 0.0048 17.3 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein AAA_17 PF13207.1 ETN98841.1 - 0.0033 18.2 0.0 0.54 11.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 ETN98841.1 - 0.0049 16.7 1.1 0.57 9.9 0.2 2.4 1 1 1 2 2 2 1 Dynamin family AAA_29 PF13555.1 ETN98841.1 - 0.0094 15.4 0.2 0.017 14.6 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 ETN98841.1 - 0.01 15.2 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_28 PF13521.1 ETN98841.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 ETN98841.1 - 0.035 13.0 0.0 0.053 12.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.1 ETN98841.1 - 0.041 14.0 0.0 0.22 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 ETN98841.1 - 0.073 13.3 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 ETN98841.1 - 0.089 12.2 0.7 0.2 11.0 0.5 1.8 1 1 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 ETN98841.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 ETN98841.1 - 0.11 12.7 0.1 0.25 11.5 0.1 1.8 1 1 0 1 1 1 0 RNA helicase DUF815 PF05673.8 ETN98841.1 - 0.11 11.3 0.0 0.21 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_23 PF13476.1 ETN98841.1 - 0.25 11.6 2.9 0.87 9.8 0.2 2.2 2 1 0 2 2 2 0 AAA domain Peptidase_C14 PF00656.17 ETN98842.1 - 1e-06 28.6 0.1 1.2e-06 28.4 0.1 1.1 1 0 0 1 1 1 1 Caspase domain NACHT PF05729.7 ETN98843.1 - 2e-11 43.8 0.0 6.6e-11 42.1 0.0 1.7 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 ETN98843.1 - 0.0025 16.7 0.1 0.0033 16.3 0.1 1.4 1 1 0 1 1 1 1 NB-ARC domain DUF2075 PF09848.4 ETN98843.1 - 0.0025 16.8 0.0 0.0046 15.9 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 ETN98843.1 - 0.0046 17.2 0.1 0.0064 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETN98843.1 - 0.0057 16.6 0.0 0.0086 16.0 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 ETN98843.1 - 0.0078 15.4 0.1 0.0095 15.1 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_19 PF13245.1 ETN98843.1 - 0.011 15.4 0.0 0.025 14.3 0.0 1.6 2 0 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 ETN98843.1 - 0.014 15.4 0.0 0.031 14.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.4 ETN98843.1 - 0.02 13.8 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Torsin PF06309.6 ETN98843.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Torsin Tn7_Tnp_TnsA_C PF08721.6 ETN98844.1 - 0.048 13.6 0.1 0.048 13.6 0.1 3.5 4 0 0 4 4 4 0 TnsA endonuclease C terminal Sec20 PF03908.8 ETN98844.1 - 0.089 12.4 8.4 0.019 14.6 1.4 2.9 2 0 0 2 2 2 0 Sec20 Menin PF05053.8 ETN98847.1 - 0.021 12.9 8.3 0.026 12.6 5.7 1.1 1 0 0 1 1 1 0 Menin Macoilin PF09726.4 ETN98847.1 - 0.35 9.1 5.4 0.43 8.7 3.8 1.0 1 0 0 1 1 1 0 Transmembrane protein SSP160 PF06933.6 ETN98847.1 - 0.68 7.8 8.8 0.76 7.6 6.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF912 PF06024.7 ETN98847.1 - 4.4 7.4 7.8 2.9 8.0 3.2 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) F-box-like PF12937.2 ETN98850.1 - 0.0014 18.2 0.1 0.0045 16.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 ETN98850.1 - 0.025 14.5 3.4 0.056 13.5 0.9 2.4 2 0 0 2 2 2 0 Leucine Rich repeat RR_TM4-6 PF06459.7 ETN98850.1 - 7.8 6.2 8.8 13 5.5 6.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC27 PF09507.5 ETN98851.1 - 7.2 5.7 48.4 8.2 5.5 33.5 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SNF2_N PF00176.18 ETN98855.1 - 2.4e-69 233.4 3.8 7.6e-69 231.7 2.6 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain LPP20 PF02169.11 ETN98855.1 - 0.00029 20.8 2.0 0.43 10.7 0.9 2.7 2 0 0 2 2 2 2 LPP20 lipoprotein FANCI_S1-cap PF14674.1 ETN98855.1 - 0.14 12.1 2.9 0.19 11.7 0.6 2.2 2 0 0 2 2 2 0 FANCI solenoid 1 cap ResIII PF04851.10 ETN98855.1 - 0.37 10.5 15.3 0.075 12.8 4.1 3.5 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit HEAT PF02985.17 ETN98856.1 - 0.0011 18.8 0.1 3.9 7.8 0.0 3.7 4 0 0 4 4 4 2 HEAT repeat DUF2435 PF10363.4 ETN98856.1 - 0.0071 16.2 5.6 5.3 6.9 0.0 5.1 4 2 1 5 5 5 1 Protein of unknown function (DUF2435) DUF573 PF04504.9 ETN98856.1 - 0.014 15.6 11.7 5.5 7.3 0.1 4.8 6 1 1 7 7 7 0 Protein of unknown function, DUF573 P16-Arc PF04699.9 ETN98856.1 - 0.029 14.4 4.1 0.93 9.4 0.1 4.0 2 1 1 3 3 3 0 ARP2/3 complex 16 kDa subunit (p16-Arc) RNA_binding PF01877.12 ETN98856.1 - 0.03 14.3 10.0 0.3 11.1 0.0 5.7 3 2 4 7 7 7 0 RNA binding BEN PF10523.4 ETN98856.1 - 0.043 13.8 9.8 2.5 8.1 0.1 5.4 6 1 1 7 7 7 0 BEN domain Prenylcys_lyase PF07156.9 ETN98857.1 - 0.00078 18.4 0.3 0.0012 17.8 0.2 1.2 1 0 0 1 1 1 1 Prenylcysteine lyase Cupin_4 PF08007.7 ETN98858.1 - 3.4e-09 36.3 0.0 5.2e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.1 ETN98858.1 - 4.3e-07 29.6 0.1 1.9e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Cupin-like domain Cupin_2 PF07883.6 ETN98858.1 - 0.0011 18.4 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Cupin domain 2OG-FeII_Oxy_5 PF13759.1 ETN98858.1 - 0.019 15.2 0.1 0.099 12.9 0.0 2.0 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase zf-C2H2 PF00096.21 ETN98860.1 - 2e-05 24.6 3.4 0.0024 18.1 0.1 6.7 7 0 0 7 7 7 3 Zinc finger, C2H2 type zf-Di19 PF05605.7 ETN98860.1 - 4.1e-05 23.6 15.9 4.7e-05 23.4 2.1 4.0 2 1 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 ETN98860.1 - 0.00079 19.6 1.0 0.00079 19.6 0.7 6.1 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 ETN98860.1 - 0.002 18.3 1.5 0.086 13.2 0.5 6.3 6 1 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 ETN98860.1 - 0.0021 18.1 6.8 0.0051 16.9 1.7 5.2 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 ETN98860.1 - 0.018 15.2 0.6 0.018 15.2 0.4 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type HET PF06985.6 ETN98860.1 - 0.098 12.8 0.4 0.14 12.3 0.3 1.3 1 1 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Plasmid_parti PF01672.11 ETN98860.1 - 0.26 11.7 4.7 5.6 7.4 0.1 2.7 2 1 1 3 3 3 0 Putative plasmid partition protein Zn-ribbon_8 PF09723.5 ETN98860.1 - 2.3 8.2 12.2 2.7 8.0 0.4 4.2 4 0 0 4 4 4 0 Zinc ribbon domain zf-HIT PF04438.11 ETN98860.1 - 4.6 6.9 18.7 2 8.1 0.2 4.5 4 0 0 4 4 4 0 HIT zinc finger TPR_12 PF13424.1 ETN98861.1 - 1e-19 70.1 0.4 2.5e-10 40.1 0.1 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETN98861.1 - 2.7e-06 26.7 3.4 1.6e-05 24.2 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETN98861.1 - 6.4e-06 25.7 0.3 0.00028 20.4 0.0 2.2 2 0 0 2 2 2 1 TPR repeat TPR_10 PF13374.1 ETN98861.1 - 1.5e-05 24.7 0.0 0.0002 21.1 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETN98861.1 - 1.8e-05 24.3 2.3 0.00036 20.2 0.1 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETN98861.1 - 5.7e-05 22.5 0.7 5.7e-05 22.5 0.5 2.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETN98861.1 - 0.0018 17.9 0.0 0.0076 15.9 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF2225 PF09986.4 ETN98861.1 - 0.012 15.1 0.3 0.015 14.7 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.13 ETN98861.1 - 0.083 12.7 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 ETN98861.1 - 0.1 13.1 0.2 0.33 11.5 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 ETN98861.1 - 0.13 12.5 0.8 4.3 7.7 0.0 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat Crystall_2 PF09076.5 ETN98862.1 - 0.13 11.9 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Beta/Gamma crystallin MethyltransfD12 PF02086.10 ETN98864.1 - 3.6e-16 59.4 1.0 4.2e-16 59.1 0.1 1.5 2 0 0 2 2 2 1 D12 class N6 adenine-specific DNA methyltransferase HSDR_N_2 PF13588.1 ETN98864.1 - 0.00032 20.4 0.8 0.004 16.9 0.2 2.4 1 1 1 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) YqaJ PF09588.5 ETN98864.1 - 0.048 13.6 0.1 0.077 12.9 0.1 1.3 1 0 0 1 1 1 0 YqaJ-like viral recombinase domain Anthrax_toxA PF03497.11 ETN98865.1 - 0.00086 19.1 2.7 0.001 18.9 1.9 1.3 1 0 0 1 1 1 1 Anthrax toxin LF subunit AlaDh_PNT_C PF01262.16 ETN98865.1 - 2.1 7.8 5.2 4 6.9 3.6 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF2360 PF10152.4 ETN98866.1 - 0.0037 17.5 7.4 0.0042 17.3 5.0 1.4 1 1 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) UPF0565 PF10561.4 ETN98866.1 - 0.26 10.1 5.0 0.41 9.4 3.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 FHIPEP PF00771.15 ETN98866.1 - 0.34 9.2 3.9 0.39 8.9 2.7 1.0 1 0 0 1 1 1 0 FHIPEP family DUF663 PF04950.7 ETN98866.1 - 0.89 8.4 6.6 1.8 7.4 3.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF663) DUF1764 PF08576.5 ETN98866.1 - 1.2 9.9 12.6 7.1 7.4 4.9 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) DUF3245 PF11595.3 ETN98866.1 - 2.7 8.2 18.0 0.52 10.5 7.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) DUF4127 PF13552.1 ETN98867.1 - 0.043 12.2 0.0 0.059 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) VIT1 PF01988.14 ETN98868.1 - 0.18 11.2 0.2 0.25 10.7 0.1 1.2 1 0 0 1 1 1 0 VIT family DUF4603 PF15376.1 ETN98868.1 - 8.7 3.3 11.4 9.5 3.2 7.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Kelch_6 PF13964.1 ETN98869.1 - 7.8e-08 32.1 1.2 0.021 14.9 0.2 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 ETN98869.1 - 8.2e-08 31.6 9.2 0.00011 21.6 0.4 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETN98869.1 - 0.00012 21.7 1.1 0.034 13.9 0.3 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 ETN98869.1 - 0.00049 20.1 0.1 0.025 14.7 0.0 2.9 3 0 0 3 3 3 1 Galactose oxidase, central domain Nucleoplasmin PF03066.10 ETN98869.1 - 0.0038 16.7 5.1 0.0038 16.7 3.6 1.7 2 0 0 2 2 2 1 Nucleoplasmin Kelch_4 PF13418.1 ETN98869.1 - 0.016 14.9 0.1 0.14 11.9 0.1 2.6 2 0 0 2 2 2 0 Galactose oxidase, central domain Radial_spoke PF04712.7 ETN98869.1 - 0.024 13.3 4.7 0.038 12.7 3.2 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein BSP_II PF05432.6 ETN98869.1 - 0.37 10.0 10.5 0.66 9.2 7.3 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Myc_N PF01056.13 ETN98869.1 - 5 6.1 8.1 7.7 5.5 5.6 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF3682 PF12446.3 ETN98869.1 - 5.5 7.2 9.2 9.4 6.5 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DNA_pol_phi PF04931.8 ETN98869.1 - 8.2 4.0 16.2 16 3.1 11.2 1.4 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.5 ETN98869.1 - 8.4 6.7 12.5 59 3.9 8.6 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain TPR_MLP1_2 PF07926.7 ETN98870.1 - 0.015 15.0 8.6 0.015 15.0 6.0 2.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Hormone_1 PF00103.15 ETN98870.1 - 0.55 9.5 16.4 1 8.6 0.9 2.5 1 1 0 2 2 2 0 Somatotropin hormone family GAGA_bind PF06217.7 ETN98870.1 - 1.1 9.2 10.5 1.3 8.9 7.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF641 PF04859.7 ETN98870.1 - 2.5 7.8 19.7 0.035 13.8 1.8 2.6 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) COLFI PF01410.13 ETN98870.1 - 2.6 7.4 12.1 0.053 12.9 0.9 2.1 1 1 0 2 2 2 0 Fibrillar collagen C-terminal domain MRP-S27 PF10037.4 ETN98870.1 - 9.4 5.0 23.5 17 4.1 16.3 1.4 1 1 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 MvaI_BcnI PF15515.1 ETN98872.1 - 1.9e-13 50.9 0.0 4.8e-12 46.3 0.0 2.3 2 0 0 2 2 2 1 MvaI/BcnI restriction endonuclease family RE_LlaMI PF09562.5 ETN98872.1 - 0.0025 17.0 0.1 0.19 10.8 0.0 2.5 2 0 0 2 2 2 2 LlaMI restriction endonuclease FAM178 PF14816.1 ETN98872.1 - 0.02 13.6 0.8 0.034 12.8 0.6 1.3 1 0 0 1 1 1 0 Family of unknown function, FAM178 DUF1912 PF08930.5 ETN98872.1 - 0.51 10.4 4.9 9.7 6.3 0.6 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1912) DUF1495 PF07381.6 ETN98873.1 - 0.092 12.4 0.0 0.48 10.1 0.0 2.3 2 0 0 2 2 2 0 Winged helix DNA-binding domain (DUF1495) Surf_Ag_VNR PF07244.10 ETN98873.1 - 0.16 12.3 2.7 1.6 9.2 0.0 3.1 3 1 0 3 3 3 0 Surface antigen variable number repeat DUF4172 PF13776.1 ETN98873.1 - 0.18 11.9 3.4 10 6.2 0.1 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4172) DUF3782 PF12644.2 ETN98873.1 - 0.44 10.3 2.5 1.8 8.4 1.7 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) Pinin_SDK_memA PF04696.8 ETN98874.1 - 0.049 13.2 4.6 0.079 12.5 3.2 1.4 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Ub-Mut7C PF14451.1 ETN98874.1 - 0.065 12.7 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 Mut7-C ubiquitin BSP_II PF05432.6 ETN98875.1 - 0.00057 19.2 10.9 0.00067 19.0 7.6 1.0 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) NOA36 PF06524.7 ETN98875.1 - 0.027 13.7 3.3 0.033 13.4 2.3 1.1 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 ETN98875.1 - 0.029 13.9 6.9 0.032 13.7 4.8 1.1 1 0 0 1 1 1 0 Nucleoplasmin Trypan_PARP PF05887.6 ETN98875.1 - 0.086 12.6 7.7 0.094 12.5 5.3 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Prothymosin PF03247.9 ETN98875.1 - 0.18 11.9 19.8 0.22 11.6 13.7 1.1 1 0 0 1 1 1 0 Prothymosin/parathymosin family ANAPC15 PF15243.1 ETN98875.1 - 0.2 11.7 8.6 0.27 11.3 6.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Daxx PF03344.10 ETN98875.1 - 0.95 7.8 10.0 0.97 7.8 6.9 1.0 1 0 0 1 1 1 0 Daxx Family CENP-B_dimeris PF09026.5 ETN98875.1 - 1.1 9.5 10.8 1.4 9.1 7.5 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Radial_spoke PF04712.7 ETN98875.1 - 1.2 7.7 9.2 1.3 7.7 6.4 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein CDC45 PF02724.9 ETN98875.1 - 2.5 6.0 5.0 2.7 5.9 3.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.9 ETN98875.1 - 2.6 7.5 5.5 2.9 7.3 3.8 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein VID27 PF08553.5 ETN98875.1 - 3.9 5.5 8.2 3.8 5.5 5.7 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Prp19_bind PF06991.6 ETN98875.1 - 4.3 6.5 12.2 4.6 6.4 8.5 1.0 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain Myc_N PF01056.13 ETN98875.1 - 5.1 6.1 7.4 6 5.9 5.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Nop14 PF04147.7 ETN98875.1 - 6 4.6 10.8 6.5 4.5 7.5 1.0 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.7 ETN98875.1 - 9.1 5.3 11.6 11 5.0 8.1 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT U-box PF04564.10 ETN98876.1 - 5.5e-07 29.4 0.1 9.4e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 U-box domain TPM PF04536.9 ETN98877.1 - 6.8e-14 51.7 0.0 8.6e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase OATP PF03137.15 ETN98878.1 - 3.5e-06 25.3 9.0 0.00017 19.8 1.5 2.7 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Na_Ca_ex PF01699.19 ETN98878.1 - 0.14 11.7 14.8 0.027 14.0 1.8 3.5 4 0 0 4 4 4 0 Sodium/calcium exchanger protein PDR_CDR PF06422.7 ETN98878.1 - 3.9 7.2 5.9 2.3 7.9 0.1 3.0 3 0 0 3 3 3 0 CDR ABC transporter FA_desaturase PF00487.19 ETN98878.1 - 9.2 5.6 9.6 0.64 9.4 1.5 2.4 1 1 0 2 2 2 0 Fatty acid desaturase Adeno_E3_CR2 PF02439.10 ETN98879.1 - 0.02 14.4 0.5 0.02 14.4 0.3 1.8 2 0 0 2 2 1 0 Adenovirus E3 region protein CR2 Peptidase_S30 PF01577.11 ETN98879.1 - 0.023 14.0 4.0 0.031 13.6 2.8 1.0 1 0 0 1 1 1 0 Potyvirus P1 protease DivIC PF04977.10 ETN98879.1 - 0.028 13.8 6.4 0.062 12.7 0.3 2.4 2 0 0 2 2 2 0 Septum formation initiator DUF1510 PF07423.6 ETN98879.1 - 0.028 13.7 0.8 0.033 13.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TMEM154 PF15102.1 ETN98879.1 - 0.035 13.8 0.5 0.058 13.1 0.3 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF2140 PF09911.4 ETN98879.1 - 0.04 13.0 2.6 0.042 13.0 1.2 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) S1FA PF04689.8 ETN98879.1 - 0.055 13.3 0.1 0.083 12.7 0.0 1.3 1 0 0 1 1 1 0 DNA binding protein S1FA Kei1 PF08552.6 ETN98879.1 - 0.063 12.9 0.4 0.07 12.7 0.3 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF1673 PF07895.6 ETN98879.1 - 0.069 12.6 2.5 0.081 12.4 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) DUF2353 PF09789.4 ETN98879.1 - 0.099 11.8 9.9 1.2 8.2 6.7 1.9 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) TPM PF04536.9 ETN98879.1 - 0.11 12.3 0.4 0.17 11.7 0.3 1.4 1 1 0 1 1 1 0 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase DUF1049 PF06305.6 ETN98879.1 - 0.12 11.8 0.2 0.28 10.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) EphA2_TM PF14575.1 ETN98879.1 - 0.13 12.6 0.6 0.21 12.0 0.4 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain tRNA_anti-like PF12869.2 ETN98879.1 - 0.13 11.7 1.6 0.23 10.9 1.1 1.6 1 1 0 1 1 1 0 tRNA_anti-like DUF837 PF05769.6 ETN98879.1 - 0.14 11.7 7.6 0.21 11.1 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF837) Mnd1 PF03962.10 ETN98879.1 - 0.16 11.5 8.5 0.2 11.2 5.9 1.1 1 0 0 1 1 1 0 Mnd1 family Lebercilin PF15619.1 ETN98879.1 - 0.27 10.6 14.5 0.2 11.0 8.3 1.7 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease MSC PF09402.5 ETN98879.1 - 0.3 9.7 4.7 0.1 11.2 0.9 1.7 1 1 1 2 2 2 0 Man1-Src1p-C-terminal domain TPR_MLP1_2 PF07926.7 ETN98879.1 - 0.39 10.4 13.0 0.62 9.8 9.0 1.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein OmpH PF03938.9 ETN98879.1 - 0.45 10.4 9.2 0.55 10.1 6.4 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2681 PF10883.3 ETN98879.1 - 1.1 9.5 12.0 0.29 11.3 2.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) RRF PF01765.14 ETN98879.1 - 1.7 8.0 8.4 1.4 8.3 4.9 1.5 1 1 0 1 1 1 0 Ribosome recycling factor CHD5 PF04420.9 ETN98879.1 - 1.8 8.2 7.5 0.38 10.3 1.4 2.0 1 1 1 2 2 2 0 CHD5-like protein M PF02370.11 ETN98879.1 - 1.8 9.1 20.2 0.77 10.3 9.3 2.7 2 0 0 2 2 2 0 M protein repeat DUF904 PF06005.7 ETN98879.1 - 2.4 8.5 17.6 0.36 11.1 3.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DUF342 PF03961.8 ETN98879.1 - 4.4 5.6 8.3 5.8 5.2 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) OAD_gamma PF04277.8 ETN98879.1 - 5.5 7.4 8.9 0.35 11.2 2.5 1.7 2 1 0 2 2 1 0 Oxaloacetate decarboxylase, gamma chain DUF948 PF06103.6 ETN98879.1 - 6.9 6.6 7.0 19 5.1 0.5 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Tho2 PF11262.3 ETN98879.1 - 7.5 5.5 12.7 1.9 7.4 2.5 2.1 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Chorein_N PF12624.2 ETN98881.1 - 2e-08 33.8 4.0 8.2e-05 22.1 0.3 2.3 1 1 1 2 2 2 2 N-terminal region of Chorein, a TM vesicle-mediated sorter Peptidase_S49_N PF08496.5 ETN98881.1 - 0.43 10.3 3.8 0.19 11.5 0.7 1.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal tRNA-synt_1c_C PF03950.13 ETN98883.1 - 2.9e-33 114.9 0.3 6.7e-33 113.8 0.2 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain AAA_32 PF13654.1 ETN98885.1 - 0.04 12.5 5.5 0.038 12.6 3.5 1.3 1 1 0 1 1 1 0 AAA domain CorA PF01544.13 ETN98885.1 - 0.051 12.6 0.4 0.074 12.0 0.3 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Syntaxin-18_N PF10496.4 ETN98885.1 - 0.055 13.2 2.0 0.14 12.0 1.4 1.8 1 1 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus Mnd1 PF03962.10 ETN98885.1 - 0.07 12.7 5.5 0.11 12.1 3.8 1.3 1 0 0 1 1 1 0 Mnd1 family Syntaxin PF00804.20 ETN98885.1 - 0.078 13.1 4.1 3.7 7.7 1.1 2.4 2 0 0 2 2 2 0 Syntaxin OmpH PF03938.9 ETN98885.1 - 0.086 12.7 9.7 0.1 12.5 6.7 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FliS PF02561.9 ETN98885.1 - 0.12 12.2 2.8 1.4 8.7 0.3 2.1 1 1 0 2 2 2 0 Flagellar protein FliS DUF1980 PF09323.5 ETN98885.1 - 0.3 10.7 2.3 0.46 10.2 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF2937 PF11157.3 ETN98885.1 - 1.2 8.4 3.6 2.7 7.3 1.5 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2937) Uds1 PF15456.1 ETN98885.1 - 1.3 9.0 8.4 0.73 9.8 1.4 2.0 1 1 1 2 2 2 0 Up-regulated During Septation DUF964 PF06133.6 ETN98885.1 - 2.6 8.1 12.0 1.6 8.7 5.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF964) Ly49 PF08391.5 ETN98885.1 - 3.2 7.8 6.5 6.2 6.9 4.5 1.5 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region Vpu PF00558.14 ETN98885.1 - 3.3 7.3 6.8 1.2 8.7 2.2 2.0 1 1 1 2 2 2 0 Vpu protein Muted PF14942.1 ETN98885.1 - 3.4 7.5 9.3 7.1 6.4 6.5 1.8 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein TMF_DNA_bd PF12329.3 ETN98885.1 - 4.8 7.0 10.3 15 5.4 1.2 2.6 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Utp14 PF04615.8 ETN98886.1 - 1.7 6.7 51.0 1.8 6.6 35.3 1.0 1 0 0 1 1 1 0 Utp14 protein SDA1 PF05285.7 ETN98886.1 - 9.7 5.3 47.6 12 5.1 33.0 1.1 1 0 0 1 1 1 0 SDA1 SPARC_Ca_bdg PF10591.4 ETN98887.1 - 0.007 16.3 1.8 0.015 15.3 1.3 1.8 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region FliH PF02108.11 ETN98887.1 - 0.036 13.9 0.2 0.088 12.6 0.1 1.7 1 1 1 2 2 2 0 Flagellar assembly protein FliH CUE PF02845.11 ETN98888.1 - 0.0061 16.0 0.2 0.0088 15.5 0.1 1.3 1 0 0 1 1 1 1 CUE domain DUF3453 PF11935.3 ETN98888.1 - 0.012 14.9 0.1 0.015 14.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3453) DUF2700 PF10912.3 ETN98888.1 - 0.11 12.5 0.1 0.16 11.9 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2700) Kelch_1 PF01344.20 ETN98889.1 - 0.0016 17.9 0.9 0.0016 17.9 0.6 2.9 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETN98889.1 - 0.042 13.6 3.5 0.057 13.1 0.2 2.8 3 0 0 3 3 3 0 Kelch motif Kelch_6 PF13964.1 ETN98889.1 - 0.058 13.6 3.4 0.49 10.6 0.2 3.0 2 1 1 3 3 3 0 Kelch motif Baculo_IE-1 PF05290.6 ETN98890.1 - 0.063 13.0 1.5 0.087 12.5 1.1 1.3 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) YlbD_coat PF14071.1 ETN98892.1 - 0.045 13.8 5.9 0.038 14.0 3.3 1.3 1 1 0 1 1 1 0 Putative coat protein DUF3336 PF11815.3 ETN98892.1 - 0.14 11.6 6.2 0.21 11.0 4.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3336) Host_attach PF10116.4 ETN98892.1 - 0.17 12.1 2.6 0.25 11.5 1.8 1.1 1 0 0 1 1 1 0 Protein required for attachment to host cells DUF506 PF04720.7 ETN98892.1 - 1.5 8.3 4.7 1.7 8.2 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Vfa1 PF08432.5 ETN98893.1 - 0.066 13.2 6.5 0.086 12.8 4.5 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DcuC PF03606.10 ETN98893.1 - 0.074 11.2 2.5 0.093 10.9 1.7 1.1 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier Helicase_RecD PF05127.9 ETN98893.1 - 0.15 11.7 2.8 0.27 10.8 2.0 1.4 1 0 0 1 1 1 0 Helicase Peptidase_S49_N PF08496.5 ETN98893.1 - 0.22 11.3 4.2 0.34 10.6 2.9 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DDHD PF02862.12 ETN98893.1 - 0.34 10.6 3.7 0.37 10.5 2.6 1.2 1 0 0 1 1 1 0 DDHD domain Med3 PF11593.3 ETN98893.1 - 0.7 9.0 9.5 0.75 8.9 6.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF3537 PF12056.3 ETN98893.1 - 1.9 7.1 6.8 2.6 6.6 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) Apis_Csd PF11671.3 ETN98895.1 - 0.015 15.1 0.3 0.019 14.7 0.2 1.2 1 0 0 1 1 1 0 Complementary sex determiner protein zf-RNPHF PF08080.7 ETN98895.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 RNPHF zinc finger WD40 PF00400.27 ETN98896.1 - 9.6e-11 41.1 0.8 0.00083 19.1 0.5 3.9 4 1 1 5 5 5 2 WD domain, G-beta repeat F420_ligase PF01996.11 ETN98896.1 - 0.032 13.2 0.0 0.037 13.0 0.0 1.1 1 0 0 1 1 1 0 F420-0:Gamma-glutamyl ligase FtsK_SpoIIIE_N PF12538.3 ETN98896.1 - 0.064 13.3 2.2 0.092 12.8 0.2 1.9 2 0 0 2 2 2 0 DNA transporter RRM_DME PF15628.1 ETN98896.1 - 0.099 12.3 0.3 1 9.0 0.0 2.2 1 1 0 2 2 2 0 RRM in Demeter fn3 PF00041.16 ETN98897.1 - 4.2e-12 46.0 3.5 1.7e-07 31.2 0.5 3.3 3 0 0 3 3 3 2 Fibronectin type III domain zf-TRAF PF02176.13 ETN98898.1 - 1.9e-06 28.1 3.3 1.9e-06 28.1 2.3 3.3 2 1 2 4 4 4 1 TRAF-type zinc finger OmpH PF03938.9 ETN98898.1 - 0.49 10.3 5.5 0.81 9.6 3.8 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) ABC_membrane PF00664.18 ETN98900.1 - 2.8e-26 92.5 0.1 3.1e-26 92.3 0.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 ETN98901.1 - 7e-13 49.0 0.0 1.6e-12 47.9 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_17 PF13207.1 ETN98901.1 - 2.3e-05 25.2 0.0 4.7e-05 24.2 0.0 1.6 2 0 0 2 2 1 1 AAA domain DUF258 PF03193.11 ETN98901.1 - 3.1e-05 23.2 0.0 4.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 ETN98901.1 - 8.9e-05 21.9 0.2 0.00016 21.1 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 ETN98901.1 - 0.00034 20.6 0.0 0.00046 20.2 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 ETN98901.1 - 0.00039 20.4 0.1 0.00064 19.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 ETN98901.1 - 0.0026 18.1 0.2 0.0041 17.4 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETN98901.1 - 0.0086 16.3 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF87 PF01935.12 ETN98901.1 - 0.014 15.2 0.2 0.028 14.2 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function DUF87 ABC_membrane PF00664.18 ETN98901.1 - 0.018 14.4 1.0 0.024 14.0 0.7 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region G-alpha PF00503.15 ETN98901.1 - 0.023 13.4 0.0 0.023 13.4 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit ATP-synt_ab PF00006.20 ETN98901.1 - 0.035 13.6 0.0 0.079 12.4 0.0 1.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.1 ETN98901.1 - 0.038 14.1 0.0 0.062 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 ETN98901.1 - 0.046 13.1 0.0 0.063 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 ETN98901.1 - 0.062 13.1 0.2 0.25 11.2 0.1 1.9 1 1 1 2 2 2 0 AAA domain MobB PF03205.9 ETN98901.1 - 0.089 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 ETN98901.1 - 0.097 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 ETN98901.1 - 0.098 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 ETN98901.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 ETN98901.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 ETN98901.1 - 0.12 12.0 0.0 0.29 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SMC_N PF02463.14 ETN98901.1 - 0.13 11.4 0.5 0.24 10.6 0.2 1.5 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain WD40 PF00400.27 ETN98902.1 - 2.5e-09 36.6 2.0 1.1e-08 34.6 0.3 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat DCR PF14047.1 ETN98904.1 - 0.11 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Dppa2/4 conserved region Ank_2 PF12796.2 ETN98906.1 - 2.7e-22 78.8 2.0 2.6e-12 46.9 0.4 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETN98906.1 - 1.7e-19 68.5 1.2 0.00028 20.5 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.1 ETN98906.1 - 4.6e-17 60.4 1.6 0.0084 16.2 0.0 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 ETN98906.1 - 6.3e-16 58.4 1.7 3.7e-05 24.1 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETN98906.1 - 1.6e-13 50.3 1.0 0.0011 19.0 0.0 4.9 4 1 1 5 5 5 4 Ankyrin repeats (many copies) C1_2 PF03107.11 ETN98906.1 - 0.0002 21.3 22.0 0.00057 19.9 0.5 3.4 3 0 0 3 3 3 2 C1 domain DUF2112 PF09885.4 ETN98906.1 - 0.13 11.9 0.0 0.49 10.0 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2112) Tmemb_18A PF09771.4 ETN98907.1 - 0.0085 16.0 1.0 0.012 15.5 0.4 1.5 1 1 0 1 1 1 1 Transmembrane protein 188 Glycos_transf_1 PF00534.15 ETN98908.1 - 1e-15 57.5 0.0 1.8e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 ETN98908.1 - 0.00015 21.9 0.0 0.00019 21.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 ETN98908.1 - 0.0016 18.6 0.0 0.0071 16.5 0.0 2.0 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glycogen_syn PF05693.8 ETN98908.1 - 0.0097 14.2 0.0 0.014 13.6 0.0 1.2 1 0 0 1 1 1 1 Glycogen synthase PspB PF06667.7 ETN98908.1 - 1.9 8.4 5.0 1.1 9.2 1.4 2.2 2 1 0 2 2 2 0 Phage shock protein B Ycf34 PF10718.4 ETN98911.1 - 0.13 12.6 0.7 7.3 7.0 0.1 2.1 2 0 0 2 2 2 0 Hypothetical chloroplast protein Ycf34 Imm11 PF15563.1 ETN98913.1 - 0.026 13.6 0.7 0.03 13.4 0.5 1.2 1 0 0 1 1 1 0 Immunity protein 11 OTCace PF00185.19 ETN98916.1 - 4.2e-16 59.2 0.1 8.7e-16 58.1 0.1 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain B-block_TFIIIC PF04182.7 ETN98916.1 - 0.071 12.9 0.6 3 7.7 0.1 2.5 2 1 0 2 2 2 0 B-block binding subunit of TFIIIC ING PF12998.2 ETN98916.1 - 0.36 11.1 4.0 0.19 11.9 1.0 1.9 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Chorismate_synt PF01264.16 ETN98917.1 - 0.019 13.4 0.3 0.024 13.1 0.2 1.1 1 0 0 1 1 1 0 Chorismate synthase Arrestin_C PF02752.17 ETN98917.1 - 0.18 11.9 3.1 0.25 11.4 2.1 1.3 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain DUF2434 PF10361.4 ETN98918.1 - 0.036 13.1 0.5 0.097 11.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2434) ODV-E18 PF10717.4 ETN98920.1 - 4.2e-05 22.8 5.0 5e-05 22.6 3.5 1.3 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 DUF1510 PF07423.6 ETN98920.1 - 0.0038 16.6 2.1 0.0042 16.4 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) OAD_gamma PF04277.8 ETN98920.1 - 0.013 15.8 15.7 0.016 15.5 10.9 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Shisa PF13908.1 ETN98920.1 - 0.028 14.6 7.7 0.031 14.4 5.3 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Baculo_11_kDa PF06143.6 ETN98920.1 - 0.069 12.5 4.4 0.1 12.0 3.1 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF929 PF06053.6 ETN98920.1 - 0.077 12.0 7.5 0.087 11.8 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF929) DUF4446 PF14584.1 ETN98920.1 - 0.14 12.0 1.9 0.15 11.8 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF843 PF05814.6 ETN98920.1 - 0.17 11.6 4.5 0.22 11.3 3.1 1.2 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) SecG PF03840.9 ETN98920.1 - 0.18 11.5 11.0 0.25 11.0 7.6 1.3 1 0 0 1 1 1 0 Preprotein translocase SecG subunit DUF1180 PF06679.7 ETN98920.1 - 0.2 11.5 3.2 0.28 11.0 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) SoxE PF06525.6 ETN98920.1 - 0.21 10.8 12.2 0.26 10.5 8.5 1.2 1 0 0 1 1 1 0 Sulfocyanin (SoxE) VP7 PF00434.13 ETN98920.1 - 0.24 10.2 6.9 0.24 10.2 4.8 1.0 1 0 0 1 1 1 0 Glycoprotein VP7 tRNA_anti-like PF12869.2 ETN98920.1 - 0.36 10.2 5.3 0.46 9.9 3.7 1.3 1 0 0 1 1 1 0 tRNA_anti-like GP41 PF00517.12 ETN98920.1 - 0.52 9.8 3.6 0.61 9.6 2.5 1.2 1 0 0 1 1 1 0 Retroviral envelope protein SKN1 PF03935.10 ETN98920.1 - 0.56 8.2 2.4 0.55 8.3 1.7 1.0 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) Sporozoite_P67 PF05642.6 ETN98920.1 - 2.1 6.1 5.9 2.3 5.9 4.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4395 PF14340.1 ETN98920.1 - 2.5 8.1 11.4 3.2 7.8 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4395) UPF0182 PF03699.8 ETN98920.1 - 2.5 5.8 7.4 2.9 5.7 5.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF2207 PF09972.4 ETN98920.1 - 3.7 6.0 5.9 3.3 6.1 4.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) HN PF00423.14 ETN98920.1 - 4.2 5.5 9.3 4.8 5.3 6.4 1.1 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase ATP-synt_8 PF00895.15 ETN98920.1 - 4.7 7.4 6.6 6.9 6.9 4.4 1.5 1 1 0 1 1 1 0 ATP synthase protein 8 Neur PF00064.13 ETN98920.1 - 8.7 4.3 8.5 8.8 4.2 5.9 1.0 1 0 0 1 1 1 0 Neuraminidase AlphaC_N PF08829.5 ETN98921.1 - 0.21 10.8 4.2 0.3 10.3 2.9 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal XAP5 PF04921.9 ETN98921.1 - 3.8 7.0 11.9 2.9 7.4 7.5 1.3 1 1 0 1 1 1 0 XAP5, circadian clock regulator MFMR PF07777.6 ETN98921.1 - 7.9 6.3 16.0 0.057 13.3 3.9 2.1 1 1 1 2 2 2 0 G-box binding protein MFMR CENP-T PF15511.1 ETN98922.1 - 0.0053 16.0 4.1 0.0073 15.6 2.8 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Myosin_tail_1 PF01576.14 ETN98924.1 - 0.00013 19.8 25.9 0.00022 19.1 6.4 2.0 1 1 1 2 2 2 2 Myosin tail Reo_sigmaC PF04582.7 ETN98924.1 - 0.0025 17.0 8.0 0.0038 16.4 5.3 1.3 1 1 0 1 1 1 1 Reovirus sigma C capsid protein CALCOCO1 PF07888.6 ETN98924.1 - 0.005 15.1 20.1 0.0069 14.7 13.9 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Nup54 PF13874.1 ETN98924.1 - 0.0088 15.7 19.0 0.012 15.2 13.2 1.3 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 GAS PF13851.1 ETN98924.1 - 0.013 14.7 28.6 0.093 11.9 19.8 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIVA PF05103.8 ETN98924.1 - 0.016 15.2 24.1 0.19 11.7 9.8 2.3 1 1 1 2 2 2 0 DivIVA protein IncA PF04156.9 ETN98924.1 - 0.028 14.0 27.9 0.14 11.7 18.1 2.0 1 1 1 2 2 2 0 IncA protein CENP-F_leu_zip PF10473.4 ETN98924.1 - 0.033 14.0 25.9 0.011 15.5 15.7 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 OmpH PF03938.9 ETN98924.1 - 0.059 13.3 25.0 0.095 12.6 17.0 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Filament PF00038.16 ETN98924.1 - 0.072 12.5 26.5 0.28 10.6 18.4 1.7 1 1 0 1 1 1 0 Intermediate filament protein VitD-bind_III PF09164.5 ETN98924.1 - 0.075 12.6 0.6 0.22 11.1 0.1 2.0 1 1 1 2 2 2 0 Vitamin D binding protein, domain III Spc7 PF08317.6 ETN98924.1 - 0.08 11.5 20.4 0.11 11.0 14.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3508 PF12018.3 ETN98924.1 - 0.08 11.9 19.2 0.051 12.5 4.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3508) Macoilin PF09726.4 ETN98924.1 - 0.1 10.8 20.8 0.12 10.6 14.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Mod_r PF07200.8 ETN98924.1 - 0.12 12.2 26.4 0.055 13.3 11.0 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein IFT57 PF10498.4 ETN98924.1 - 0.15 10.7 27.8 1.2 7.7 19.2 1.9 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 HapK PF11639.3 ETN98924.1 - 0.16 12.5 1.3 16 6.2 0.0 2.3 1 1 1 2 2 2 0 REDY-like protein HapK DUF4201 PF13870.1 ETN98924.1 - 0.2 11.0 26.2 1.3 8.4 6.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DivIC PF04977.10 ETN98924.1 - 0.22 11.0 24.7 0.4 10.1 2.0 3.5 1 1 2 3 3 3 0 Septum formation initiator DUF4200 PF13863.1 ETN98924.1 - 0.23 11.4 27.7 0.63 9.9 10.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.7 ETN98924.1 - 0.24 11.1 35.0 1.5 8.5 9.7 2.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3086 PF11285.3 ETN98924.1 - 0.28 9.9 11.2 0.34 9.6 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) Prominin PF05478.6 ETN98924.1 - 0.28 8.6 12.6 0.38 8.2 8.8 1.2 1 0 0 1 1 1 0 Prominin DUF111 PF01969.12 ETN98924.1 - 0.29 9.9 2.9 0.36 9.5 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF111 APG6 PF04111.7 ETN98924.1 - 0.32 10.0 29.3 0.074 12.0 16.7 1.7 1 1 0 1 1 1 0 Autophagy protein Apg6 MbeD_MobD PF04899.7 ETN98924.1 - 0.33 10.8 22.7 0.1 12.4 1.5 3.5 1 1 2 3 3 3 0 MbeD/MobD like Atg14 PF10186.4 ETN98924.1 - 0.33 9.8 21.3 0.5 9.2 14.8 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 YjcZ PF13990.1 ETN98924.1 - 0.54 9.3 15.2 0.68 9.0 10.5 1.1 1 0 0 1 1 1 0 YjcZ-like protein AAA_13 PF13166.1 ETN98924.1 - 0.64 8.4 19.7 0.87 7.9 13.7 1.1 1 0 0 1 1 1 0 AAA domain DUF972 PF06156.8 ETN98924.1 - 0.72 10.2 22.3 0.77 10.1 8.7 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Seryl_tRNA_N PF02403.17 ETN98924.1 - 0.73 9.8 18.3 1.2 9.1 8.4 2.6 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain HrpB7 PF09486.5 ETN98924.1 - 0.74 9.7 11.5 2.4 8.0 8.0 1.8 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) HAUS6_N PF14661.1 ETN98924.1 - 0.74 9.1 21.6 0.84 8.9 9.9 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Nup88 PF10168.4 ETN98924.1 - 0.86 7.3 14.8 0.94 7.2 10.3 1.0 1 0 0 1 1 1 0 Nuclear pore component EzrA PF06160.7 ETN98924.1 - 0.94 7.5 24.6 3.8 5.5 11.2 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Phage_lysis PF03245.8 ETN98924.1 - 0.97 9.4 17.3 2.1 8.3 0.3 2.3 2 1 0 2 2 2 0 Bacteriophage Rz lysis protein DUF3584 PF12128.3 ETN98924.1 - 1.1 6.5 25.2 2 5.6 17.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Lipoprotein_6 PF01441.14 ETN98924.1 - 1.2 8.9 13.2 3.6 7.3 4.4 2.4 1 1 1 2 2 2 0 Lipoprotein Rootletin PF15035.1 ETN98924.1 - 1.5 8.7 29.3 21 5.0 20.1 2.6 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion CENP-Q PF13094.1 ETN98924.1 - 1.8 8.5 25.2 6.4 6.7 17.5 2.0 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Cluap1 PF10234.4 ETN98924.1 - 1.9 7.6 19.7 7.8 5.6 13.6 1.8 1 1 0 1 1 1 0 Clusterin-associated protein-1 Phage_GP20 PF06810.6 ETN98924.1 - 2.6 7.4 28.4 1.9 7.8 2.7 2.9 1 1 2 3 3 3 0 Phage minor structural protein GP20 Tropomyosin_1 PF12718.2 ETN98924.1 - 2.8 7.7 28.3 32 4.3 19.1 2.1 1 1 0 1 1 1 0 Tropomyosin like U1snRNP70_N PF12220.3 ETN98924.1 - 3.1 8.1 17.2 0.19 12.0 1.2 2.6 2 1 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF3683 PF12447.3 ETN98924.1 - 3.4 7.5 8.3 2.7 7.8 1.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3683) DUF948 PF06103.6 ETN98924.1 - 3.4 7.6 11.1 2.9 7.8 4.9 2.6 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Striatin PF08232.7 ETN98924.1 - 3.7 7.8 23.1 5.6 7.2 0.1 2.3 1 1 1 2 2 2 0 Striatin family DUF4164 PF13747.1 ETN98924.1 - 4 7.6 14.5 0.75 9.9 2.8 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) DUF3450 PF11932.3 ETN98924.1 - 4.9 6.3 26.5 8.2 5.6 11.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF342 PF03961.8 ETN98924.1 - 5.1 5.3 21.8 1.1 7.5 8.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Sec2p PF06428.6 ETN98924.1 - 5.5 6.8 21.1 0.043 13.6 4.8 2.4 1 1 1 2 2 1 0 GDP/GTP exchange factor Sec2p Phage_GPO PF05929.6 ETN98924.1 - 6.1 6.0 17.6 7.4 5.7 11.2 1.7 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF1664 PF07889.7 ETN98924.1 - 6.3 6.6 15.1 8.5 6.1 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) COLFI PF01410.13 ETN98924.1 - 6.7 6.0 13.6 8.5 5.7 9.4 1.1 1 0 0 1 1 1 0 Fibrillar collagen C-terminal domain FliD_C PF07195.7 ETN98924.1 - 7.1 5.8 19.9 20 4.4 11.6 2.5 1 1 1 3 3 3 0 Flagellar hook-associated protein 2 C-terminus Peptidase_S64 PF08192.6 ETN98924.1 - 7.9 4.6 14.9 8.7 4.5 10.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 Prefoldin PF02996.12 ETN98924.1 - 8 6.1 22.3 3.7 7.2 1.2 3.5 1 1 2 3 3 3 0 Prefoldin subunit DUF4446 PF14584.1 ETN98924.1 - 9 6.1 16.4 2 8.2 1.5 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) bZIP_2 PF07716.10 ETN98924.1 - 9.3 6.1 22.9 0.7 9.7 1.2 3.6 3 1 0 3 3 3 0 Basic region leucine zipper Pkinase PF00069.20 ETN98926.1 - 2.3e-43 148.2 0.3 2.3e-43 148.2 0.2 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETN98926.1 - 2.4e-29 102.2 0.0 3.2e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETN98926.1 - 1.3e-05 24.3 0.0 3.4e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 ETN98926.1 - 0.0033 16.3 0.1 0.0059 15.4 0.1 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 Choline_kinase PF01633.15 ETN98926.1 - 2.4 7.6 8.0 0.053 13.0 0.4 1.9 2 1 0 2 2 2 0 Choline/ethanolamine kinase NAAA-beta PF15508.1 ETN98927.1 - 0.0013 19.0 4.2 0.064 13.6 0.0 5.4 2 2 4 7 7 7 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Uteroglobin PF01099.12 ETN98927.1 - 0.43 10.4 6.3 0.18 11.6 0.2 3.5 3 0 0 3 3 3 0 Uteroglobin family Proteasome PF00227.21 ETN98928.1 - 1.8e-28 99.1 0.0 2.3e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit HSP90 PF00183.13 ETN98929.1 - 2.4e-36 125.2 10.4 6.5e-19 67.7 1.3 2.1 1 1 1 2 2 2 2 Hsp90 protein DUF2012 PF09430.5 ETN98929.1 - 0.003 17.3 1.1 0.0068 16.2 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) Gemini_AL1 PF00799.15 ETN98929.1 - 0.0092 15.8 1.1 0.37 10.6 0.0 2.5 2 0 0 2 2 2 1 Geminivirus Rep catalytic domain Asp-B-Hydro_N PF05279.6 ETN98930.1 - 0.75 9.5 10.0 0.87 9.3 6.9 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Otopetrin PF03189.8 ETN98930.1 - 1.4 7.8 4.2 1.8 7.5 2.9 1.0 1 0 0 1 1 1 0 Otopetrin Herpes_UL95 PF03038.9 ETN98930.1 - 1.6 7.5 8.2 1.9 7.2 5.7 1.0 1 0 0 1 1 1 0 UL95 family Mem_trans PF03547.13 ETN98930.1 - 9 4.4 8.7 11 4.1 6.0 1.0 1 0 0 1 1 1 0 Membrane transport protein MIP-T3 PF10243.4 ETN98931.1 - 0.013 14.0 24.9 0.013 14.0 17.3 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Sigma70_ner PF04546.8 ETN98931.1 - 0.026 14.1 14.6 0.03 13.9 10.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region POX PF07526.6 ETN98931.1 - 0.042 14.0 7.3 0.042 14.0 5.1 1.1 1 0 0 1 1 1 0 Associated with HOX Vfa1 PF08432.5 ETN98931.1 - 0.047 13.7 23.7 0.052 13.5 16.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop14 PF04147.7 ETN98931.1 - 0.054 11.4 21.2 0.053 11.4 14.7 1.0 1 0 0 1 1 1 0 Nop14-like family ATP-synt_E PF05680.7 ETN98931.1 - 0.095 12.6 7.1 0.13 12.2 4.9 1.3 1 0 0 1 1 1 0 ATP synthase E chain Daxx PF03344.10 ETN98931.1 - 0.12 10.7 18.6 0.13 10.6 12.9 1.1 1 0 0 1 1 1 0 Daxx Family Upf2 PF04050.9 ETN98931.1 - 0.15 11.8 20.0 0.16 11.6 13.8 1.0 1 0 0 1 1 1 0 Up-frameshift suppressor 2 DUF3438 PF11920.3 ETN98931.1 - 0.16 10.7 3.0 0.22 10.3 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) U79_P34 PF03064.11 ETN98931.1 - 0.22 10.9 15.7 0.21 11.1 10.9 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 SMN PF06003.7 ETN98931.1 - 0.29 10.2 8.5 0.33 9.9 5.9 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DUF1510 PF07423.6 ETN98931.1 - 0.31 10.3 25.1 0.41 9.9 17.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 ETN98931.1 - 0.39 8.6 21.3 0.39 8.6 14.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.3 ETN98931.1 - 0.4 9.2 12.4 0.44 9.0 8.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RNA_polI_A34 PF08208.6 ETN98931.1 - 0.47 10.1 31.5 0.58 9.7 21.9 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 TRAP_alpha PF03896.11 ETN98931.1 - 0.52 9.2 11.9 0.54 9.2 8.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2722 PF10846.3 ETN98931.1 - 0.53 9.2 13.7 0.56 9.1 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Sec62 PF03839.11 ETN98931.1 - 0.59 9.4 17.6 0.64 9.3 12.2 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 YqfQ PF14181.1 ETN98931.1 - 0.6 10.1 18.8 0.77 9.7 13.0 1.1 1 0 0 1 1 1 0 YqfQ-like protein RR_TM4-6 PF06459.7 ETN98931.1 - 0.65 9.8 16.3 0.71 9.7 11.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Raftlin PF15250.1 ETN98931.1 - 0.68 8.3 9.6 0.75 8.2 6.6 1.0 1 0 0 1 1 1 0 Raftlin TFIIF_alpha PF05793.7 ETN98931.1 - 0.73 8.1 28.5 0.73 8.1 19.8 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4637 PF15470.1 ETN98931.1 - 0.75 9.3 12.3 0.99 8.9 8.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DDHD PF02862.12 ETN98931.1 - 0.78 9.4 10.3 0.91 9.2 7.1 1.1 1 0 0 1 1 1 0 DDHD domain DUF3537 PF12056.3 ETN98931.1 - 0.81 8.3 3.0 0.93 8.1 2.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) SpoIIIAH PF12685.2 ETN98931.1 - 0.83 9.1 14.9 0.89 9.0 10.3 1.0 1 0 0 1 1 1 0 SpoIIIAH-like protein Pox_Ag35 PF03286.9 ETN98931.1 - 0.88 9.0 19.1 0.98 8.9 13.2 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Tom37_C PF11801.3 ETN98931.1 - 1.2 8.9 9.0 1.5 8.6 6.2 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain Zip PF02535.17 ETN98931.1 - 1.3 7.9 6.2 1.4 7.8 4.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Rtf2 PF04641.7 ETN98931.1 - 1.4 8.0 17.6 1.4 8.0 12.2 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Glyco_transf_15 PF01793.11 ETN98931.1 - 1.9 7.3 10.6 2.2 7.1 7.4 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Atrophin-1 PF03154.10 ETN98931.1 - 1.9 6.5 16.8 2.4 6.1 11.6 1.1 1 0 0 1 1 1 0 Atrophin-1 family eIF-3c_N PF05470.7 ETN98931.1 - 2.8 5.9 16.4 3 5.8 11.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus GAGA_bind PF06217.7 ETN98931.1 - 2.9 7.7 13.1 3 7.7 9.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Peroxin-13_N PF04088.8 ETN98931.1 - 3.1 7.7 4.4 4.4 7.2 3.1 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region RNA_pol_Rpc4 PF05132.9 ETN98931.1 - 3.2 7.7 16.8 5.3 7.0 11.6 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 SAPS PF04499.10 ETN98931.1 - 3.3 6.2 11.4 3.3 6.2 7.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FLO_LFY PF01698.11 ETN98931.1 - 3.5 6.3 13.6 3.8 6.2 9.5 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF2956 PF11169.3 ETN98931.1 - 3.5 7.6 15.7 4.8 7.2 10.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) TEX19 PF15553.1 ETN98931.1 - 3.9 7.3 7.7 4.5 7.1 5.3 1.1 1 0 0 1 1 1 0 Testis-expressed protein 19 Packaging_FI PF14000.1 ETN98931.1 - 3.9 7.6 11.9 4.9 7.3 8.3 1.1 1 0 0 1 1 1 0 DNA packaging protein FI VID27 PF08553.5 ETN98931.1 - 4.7 5.3 15.9 4.9 5.2 11.0 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF2413 PF10310.4 ETN98931.1 - 4.7 5.9 16.6 5.7 5.6 11.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Paf1 PF03985.8 ETN98931.1 - 5.2 5.6 24.8 6.4 5.4 17.2 1.0 1 0 0 1 1 1 0 Paf1 DUF913 PF06025.7 ETN98931.1 - 5.5 5.6 6.8 5.7 5.5 4.7 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) EIIBC-GUT_N PF03612.9 ETN98931.1 - 5.6 6.5 6.0 7.9 6.0 4.1 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus HSP90 PF00183.13 ETN98931.1 - 5.7 5.2 23.5 6.5 5.0 16.3 1.1 1 0 0 1 1 1 0 Hsp90 protein AIF_C PF14721.1 ETN98931.1 - 5.7 7.1 9.2 7.2 6.8 6.3 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term RRN3 PF05327.6 ETN98931.1 - 7.4 4.5 15.7 7.3 4.5 10.9 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pox_RNA_Pol_19 PF05320.7 ETN98931.1 - 7.4 6.2 14.6 8.9 6.0 10.1 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF3530 PF12048.3 ETN98931.1 - 7.9 5.3 9.7 8.8 5.2 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) SID-1_RNA_chan PF13965.1 ETN98931.1 - 8.9 4.3 6.3 9.9 4.1 4.4 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 NPR3 PF03666.8 ETN98931.1 - 9.6 4.6 14.3 10 4.5 9.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3464 PF11947.3 ETN98931.1 - 9.7 5.6 11.0 11 5.4 7.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF4661 PF15576.1 ETN98932.1 - 0.015 14.9 3.4 0.016 14.8 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) DUF445 PF04286.7 ETN98932.1 - 0.92 8.9 4.7 1 8.8 3.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Kelch_6 PF13964.1 ETN98934.1 - 0.023 14.8 0.3 0.31 11.2 0.0 2.8 3 1 1 4 4 4 0 Kelch motif PRP38 PF03371.10 ETN98934.1 - 0.19 11.3 1.5 0.24 10.9 1.1 1.3 1 1 0 1 1 1 0 PRP38 family Ank_2 PF12796.2 ETN98935.1 - 0.01 16.1 0.0 0.02 15.1 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) DUF2201_N PF13203.1 ETN98935.1 - 0.72 8.9 4.8 0.45 9.6 2.2 1.4 1 1 0 1 1 1 0 Putative metallopeptidase domain DUF2344 PF10105.4 ETN98935.1 - 0.85 9.0 3.9 0.78 9.1 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) HDAC4_Gln PF12203.3 ETN98935.1 - 7.1 6.6 8.2 0.25 11.2 0.3 2.4 2 1 1 3 3 3 0 Glutamine rich N terminal domain of histone deacetylase 4 PT PF04886.7 ETN98937.1 - 6.4e-95 310.1 472.0 2.4e-07 29.9 12.4 21.4 3 2 12 15 15 15 13 PT repeat ASL_C PF08328.6 ETN98938.1 - 0.19 11.6 2.9 0.35 10.7 0.1 2.6 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminal Sec6 PF06046.8 ETN98940.1 - 0.011 13.8 0.4 0.011 13.8 0.2 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec6 DUF2205 PF10224.4 ETN98940.1 - 0.062 12.8 0.7 0.1 12.1 0.5 1.5 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) CMAS PF02353.15 ETN98940.1 - 0.067 12.2 0.2 0.078 12.0 0.1 1.0 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF465 PF04325.8 ETN98940.1 - 0.15 11.8 0.8 0.28 10.9 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF465) Poxvirus_B22R PF04395.7 ETN98941.1 - 0.13 11.7 2.7 0.15 11.5 1.8 1.2 1 0 0 1 1 1 0 Poxvirus B22R protein zf-ISL3 PF14690.1 ETN98942.1 - 0.013 15.5 2.3 0.013 15.5 1.6 2.2 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Molybdop_Fe4S4 PF04879.11 ETN98942.1 - 0.015 15.0 0.2 0.047 13.5 0.2 1.8 1 0 0 1 1 1 0 Molybdopterin oxidoreductase Fe4S4 domain HTS PF04204.11 ETN98942.1 - 0.093 11.4 0.1 0.15 10.7 0.1 1.2 1 0 0 1 1 1 0 Homoserine O-succinyltransferase Tubulin PF00091.20 ETN98943.1 - 6.7e-33 114.3 0.1 7.4e-24 84.7 0.0 2.3 1 1 1 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETN98943.1 - 4.4e-08 33.2 0.1 1.6e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 Tubulin C-terminal domain DEP PF00610.16 ETN98944.1 - 1.1e-17 63.4 0.2 1.8e-10 40.4 0.0 2.7 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) EF-hand_7 PF13499.1 ETN98944.1 - 6.6e-06 26.1 0.5 2.4e-05 24.3 0.4 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_10 PF14788.1 ETN98944.1 - 0.0015 18.1 3.2 0.75 9.5 0.0 3.6 4 0 0 4 4 4 2 EF hand EF-hand_1 PF00036.27 ETN98944.1 - 0.0021 17.2 0.3 2.1 7.8 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 ETN98944.1 - 0.0089 15.8 0.1 5.3 7.2 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain WD40 PF00400.27 ETN98945.1 - 4.9e-11 42.0 0.2 1.1e-10 40.9 0.1 1.6 1 0 0 1 1 1 1 WD domain, G-beta repeat Exo_endo_phos_2 PF14529.1 ETN98946.1 - 0.022 14.3 2.0 0.084 12.4 0.0 2.4 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase Filament_head PF04732.9 ETN98946.1 - 0.086 13.5 0.5 0.16 12.7 0.4 1.4 1 0 0 1 1 1 0 Intermediate filament head (DNA binding) region TPR_11 PF13414.1 ETN98947.1 - 0.07 12.7 3.6 1.9 8.1 0.7 2.5 2 1 0 2 2 2 0 TPR repeat FTA4 PF13093.1 ETN98947.1 - 0.31 10.4 7.6 0.12 11.8 0.1 2.1 1 1 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Pox_RNA_Pol_19 PF05320.7 ETN98947.1 - 1.7 8.4 6.3 0.76 9.5 2.1 1.9 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit TPR_6 PF13174.1 ETN98947.1 - 3.5 8.3 6.6 2 9.0 0.9 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETN98947.1 - 3.9 7.6 6.9 4.4 7.4 1.6 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.27 ETN98948.1 - 2.8e-05 23.8 0.0 4.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 WD domain, G-beta repeat CPSF_A PF03178.10 ETN98948.1 - 0.025 13.6 0.0 0.031 13.3 0.0 1.1 1 0 0 1 1 1 0 CPSF A subunit region HGD-D PF06050.8 ETN98950.1 - 0.032 13.0 0.0 0.035 12.9 0.0 1.0 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component PD40 PF07676.7 ETN98951.1 - 0.00015 21.3 0.3 3.1 7.5 0.0 4.6 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat WD40 PF00400.27 ETN98951.1 - 0.0031 17.3 0.1 16 5.5 0.0 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 ETN98951.1 - 0.009 14.8 0.8 2.6 6.7 0.2 2.4 1 1 0 2 2 2 2 Coatomer WD associated region Nbas_N PF15492.1 ETN98951.1 - 0.039 13.0 0.1 12 4.8 0.0 3.1 2 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 ETN98951.1 - 0.082 12.2 3.8 7.5 5.9 0.1 4.5 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature GTP_EFTU_D4 PF14578.1 ETN98951.1 - 0.11 12.1 0.1 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 4 DASH_Duo1 PF08651.5 ETN98954.1 - 0.0077 15.7 0.8 0.012 15.1 0.2 1.6 2 0 0 2 2 2 1 DASH complex subunit Duo1 Sod_Ni PF09055.6 ETN98954.1 - 0.084 13.2 2.1 0.18 12.1 0.2 2.1 2 1 0 2 2 2 0 Nickel-containing superoxide dismutase DUF2499 PF10693.4 ETN98954.1 - 0.15 12.0 3.6 0.17 11.9 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2499) HTH_44 PF14641.1 ETN98955.1 - 0.008 16.1 0.4 0.013 15.4 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 Afaf PF15339.1 ETN98956.1 - 0.0045 16.5 0.2 0.0053 16.3 0.1 1.0 1 0 0 1 1 1 1 Acrosome formation-associated factor zf-RVT PF13966.1 ETN98959.1 - 0.00055 20.1 1.5 0.00055 20.1 1.0 2.0 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase zf-CCHC PF00098.18 ETN98959.1 - 0.004 17.0 1.9 0.004 17.0 1.3 2.7 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC_4 PF14392.1 ETN98959.1 - 0.0072 15.9 5.5 0.18 11.4 1.1 2.8 2 0 0 2 2 2 2 Zinc knuckle Ribosomal_L40e PF01020.12 ETN98959.1 - 4.2 7.0 16.0 0.34 10.5 6.3 2.7 3 0 0 3 3 3 0 Ribosomal L40e family RNase_P_p30 PF01876.11 ETN98960.1 - 0.066 12.4 0.0 0.92 8.7 0.0 2.3 2 0 0 2 2 2 0 RNase P subunit p30 TPR_12 PF13424.1 ETN98961.1 - 1.4e-34 117.8 5.4 1.8e-24 85.4 1.0 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETN98961.1 - 1.4e-16 59.2 6.5 7.3e-11 41.1 1.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETN98961.1 - 2.3e-16 59.1 1.4 1.7e-09 37.2 0.1 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETN98961.1 - 2.8e-15 54.8 1.3 9.7e-10 37.5 0.2 2.5 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETN98961.1 - 1.6e-14 53.2 1.9 2.4e-14 52.7 1.0 1.5 2 0 0 2 2 1 1 TPR repeat TPR_2 PF07719.12 ETN98961.1 - 3.2e-14 51.6 5.0 2e-08 33.5 0.5 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETN98961.1 - 8.6e-14 50.2 9.9 2e-09 36.5 2.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETN98961.1 - 1.3e-10 40.6 2.8 1.4e-05 24.9 0.1 3.2 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETN98961.1 - 4.9e-08 33.4 0.0 0.0026 18.4 0.0 2.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_3 PF07720.7 ETN98961.1 - 6.5e-08 32.2 4.5 0.00061 19.5 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETN98961.1 - 1.8e-06 28.0 0.0 0.0096 16.4 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat PPR PF01535.15 ETN98961.1 - 7.4e-06 25.5 1.4 0.00079 19.2 0.1 2.9 3 0 0 3 3 3 1 PPR repeat TPR_6 PF13174.1 ETN98961.1 - 0.00018 21.7 0.4 0.03 14.7 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 ETN98961.1 - 0.0002 21.4 4.4 0.0021 18.1 2.3 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.1 ETN98961.1 - 0.012 14.7 0.1 0.014 14.5 0.0 1.1 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP PPR_2 PF13041.1 ETN98961.1 - 0.022 14.7 0.3 0.24 11.3 0.0 2.4 3 0 0 3 3 3 0 PPR repeat family DUF627 PF04781.7 ETN98961.1 - 0.023 14.3 0.5 5.2 6.7 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF627) TPR_19 PF14559.1 ETN98961.1 - 0.023 14.9 0.1 0.057 13.7 0.0 1.7 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF3450 PF11932.3 ETN98961.1 - 0.029 13.6 0.6 2.4 7.3 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) MIT PF04212.13 ETN98961.1 - 0.033 14.0 0.7 0.033 14.0 0.5 1.8 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Sel1 PF08238.7 ETN98961.1 - 0.048 14.3 1.2 0.39 11.4 0.2 2.3 2 0 0 2 2 2 0 Sel1 repeat Fis1_TPR_C PF14853.1 ETN98961.1 - 0.052 13.4 5.1 1.6 8.6 0.3 2.3 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.4 ETN98961.1 - 0.059 12.6 0.3 0.35 10.1 0.0 2.2 2 0 0 2 2 2 0 SHNi-TPR RPN7 PF10602.4 ETN98961.1 - 0.074 12.4 0.9 0.15 11.4 0.1 1.7 1 1 1 2 2 2 0 26S proteasome subunit RPN7 DUF357 PF04010.8 ETN98961.1 - 0.23 11.1 4.7 4.2 7.1 0.3 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF357) DSPc PF00782.15 ETN98962.1 - 6e-13 48.5 0.0 7.7e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 ETN98962.1 - 4.7e-06 26.1 0.3 9e-06 25.1 0.1 1.5 1 1 1 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 ETN98962.1 - 0.00069 19.6 0.0 0.00069 19.6 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 ETN98962.1 - 0.0013 19.0 0.0 0.0015 18.8 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family RE_HindVP PF09519.5 ETN98962.1 - 0.046 12.6 0.0 0.048 12.5 0.0 1.1 1 0 0 1 1 1 0 HindVP restriction endonuclease Y_phosphatase2 PF03162.8 ETN98962.1 - 0.053 12.8 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family LAGLIDADG_1 PF00961.14 ETN98964.1 - 4 8.0 8.6 0.31 11.6 0.6 2.5 1 1 1 2 2 2 0 LAGLIDADG endonuclease SAC3 PF12209.3 ETN98965.1 - 0.077 13.1 0.4 0.16 12.0 0.3 1.5 1 0 0 1 1 1 0 Leucine permease transcriptional regulator helical domain PT PF04886.7 ETN98966.1 - 7.8e-18 63.5 68.4 0.00011 21.3 2.8 4.8 1 1 1 2 2 2 1 PT repeat DUF3071 PF11268.3 ETN98967.1 - 0.0081 15.9 1.7 0.0096 15.6 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3071) DUF4404 PF14357.1 ETN98967.1 - 0.47 10.9 5.0 0.13 12.7 1.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Spore_III_AF PF09581.5 ETN98967.1 - 0.87 9.4 8.3 0.99 9.2 5.8 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) DUF883 PF05957.8 ETN98967.1 - 1.2 9.5 3.9 2.2 8.7 0.5 2.1 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) ApoO PF09769.4 ETN98967.1 - 5 6.8 6.8 8.1 6.1 4.7 1.4 1 1 0 1 1 1 0 Apolipoprotein O ATP-synt_B PF00430.13 ETN98967.1 - 7 6.4 9.4 3.4 7.4 2.2 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DUF2408 PF10303.4 ETN98969.1 - 0.038 14.1 0.8 0.07 13.2 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) FrpC PF06901.7 ETN98970.1 - 0.059 12.8 0.0 0.062 12.8 0.0 1.2 1 0 0 1 1 1 0 RTX iron-regulated protein FrpC DUF1699 PF08004.6 ETN98970.1 - 0.092 12.2 0.2 3.8 7.0 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1699) Cluap1 PF10234.4 ETN98970.1 - 0.11 11.7 0.3 0.15 11.2 0.2 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Nro1 PF12753.2 ETN98971.1 - 0.002 17.1 0.0 0.0027 16.7 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 Lipoprotein_17 PF04200.7 ETN98972.1 - 0.14 12.3 4.3 0.17 12.0 3.0 1.1 1 0 0 1 1 1 0 Lipoprotein associated domain dUTPase PF00692.14 ETN98973.1 - 9.5e-36 122.1 0.0 4.8e-24 84.2 0.0 2.1 2 0 0 2 2 2 2 dUTPase WD40 PF00400.27 ETN98975.1 - 1.2e-06 28.1 0.4 0.00012 21.8 0.8 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat YmaF PF12788.2 ETN98976.1 - 0.014 15.5 0.2 0.014 15.5 0.2 2.1 2 0 0 2 2 2 0 YmaF family P3A PF08727.6 ETN98976.1 - 0.038 13.3 0.1 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 Poliovirus 3A protein like Ribosomal_L18_c PF14204.1 ETN98976.1 - 0.67 10.5 8.8 1.2 9.6 6.1 1.4 1 0 0 1 1 1 0 Ribosomal L18 C-terminal region DUF3464 PF11947.3 ETN98976.1 - 2.6 7.5 8.2 3.8 6.9 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) CAP_GLY PF01302.20 ETN98977.1 - 0.079 12.6 0.0 0.19 11.4 0.0 1.6 2 0 0 2 2 2 0 CAP-Gly domain TPR_12 PF13424.1 ETN98980.1 - 7.9e-09 35.3 0.0 0.0013 18.5 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETN98980.1 - 0.097 12.3 0.3 0.21 11.2 0.2 1.6 1 0 0 1 1 1 0 TPR repeat TPR_1 PF00515.23 ETN98980.1 - 0.19 11.3 1.2 2.4 7.9 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.27 ETN98982.1 - 5.1e-30 102.2 7.3 9.5e-12 44.3 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN98982.1 - 3.7e-06 25.3 0.8 0.0072 14.5 0.0 2.9 1 1 2 3 3 3 3 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETN98982.1 - 0.0011 18.8 0.0 0.67 9.9 0.0 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF3601) DUF4221 PF13970.1 ETN98982.1 - 0.0035 16.7 1.2 0.0055 16.0 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4221) Kelch_6 PF13964.1 ETN98982.1 - 0.042 14.0 3.7 6.7 7.0 0.0 3.6 1 1 1 2 2 2 0 Kelch motif Baculo_VP39 PF04501.7 ETN98982.1 - 0.089 11.7 0.1 2 7.3 0.0 2.5 2 1 1 3 3 3 0 Baculovirus major capsid protein VP39 VPR PF00522.13 ETN98983.1 - 0.18 11.6 2.1 1.4 8.7 0.3 2.4 2 0 0 2 2 2 0 VPR/VPX protein S-antigen PF05756.6 ETN98986.1 - 3.8 7.5 14.9 1.3 9.0 4.2 3.3 3 0 0 3 3 3 0 S-antigen protein WD40 PF00400.27 ETN98987.1 - 1.1e-62 205.7 30.1 9.4e-11 41.1 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETN98987.1 - 9.4e-09 33.9 6.1 0.00031 19.0 0.4 4.5 1 1 5 6 6 6 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETN98987.1 - 1.9e-08 33.0 0.7 0.0003 19.2 0.0 3.6 1 1 3 4 4 4 3 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETN98987.1 - 2.8e-05 23.0 15.5 0.045 12.4 0.8 4.8 1 1 3 4 4 4 4 Nup133 N terminal like Hira PF07569.6 ETN98987.1 - 0.005 16.0 4.0 0.45 9.6 0.0 4.0 3 1 2 5 5 5 1 TUP1-like enhancer of split PQQ_2 PF13360.1 ETN98987.1 - 0.017 14.5 0.4 0.16 11.3 0.2 2.3 1 1 0 1 1 1 0 PQQ-like domain PD40 PF07676.7 ETN98987.1 - 0.34 10.6 3.7 24 4.7 0.0 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat S6PP PF05116.8 ETN98988.1 - 0.00084 18.7 1.1 0.0045 16.3 0.0 2.0 1 1 1 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase WD40 PF00400.27 ETN98989.1 - 3.4e-41 137.6 11.9 4.7e-10 38.9 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETN98989.1 - 9.8e-09 33.8 0.3 0.0011 17.1 0.0 3.2 2 1 1 3 3 3 3 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETN98989.1 - 0.0054 16.1 2.9 0.027 13.8 0.3 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4221) HAD PF12710.2 ETN98989.1 - 0.11 12.6 0.1 0.62 10.1 0.1 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase RhoGAP PF00620.22 ETN98990.1 - 0.00019 21.0 0.0 0.00031 20.3 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain V-SNARE PF05008.10 ETN98991.1 - 1.3 9.1 9.3 0.35 11.0 1.7 2.6 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus CENP-Q PF13094.1 ETN98991.1 - 1.6 8.6 6.7 2.3 8.2 4.6 1.3 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Spt5_N PF11942.3 ETN98991.1 - 4.8 7.8 5.4 5.4 7.7 0.6 2.2 1 1 1 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Exo_endo_phos_2 PF14529.1 ETN98992.1 - 9.6e-09 34.8 0.4 1.5e-08 34.2 0.3 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase WD40 PF00400.27 ETN98993.1 - 2.6e-20 71.4 8.9 2.6e-10 39.7 0.9 2.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETN98993.1 - 0.00098 17.3 0.2 0.0017 16.6 0.1 1.3 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Peptidase_S66 PF02016.10 ETN98993.1 - 0.056 12.3 0.0 0.086 11.7 0.0 1.3 1 0 0 1 1 1 0 LD-carboxypeptidase MCM_N PF14551.1 ETN98993.1 - 0.16 12.4 0.5 0.23 11.9 0.3 1.4 1 1 0 1 1 1 0 MCM N-terminal domain Papilloma_E5 PF03025.9 ETN98993.1 - 0.55 10.2 4.1 1.1 9.2 2.9 1.5 1 0 0 1 1 1 0 Papillomavirus E5 WD40 PF00400.27 ETN98994.1 - 5.9e-19 67.1 4.7 1.3e-09 37.5 0.2 2.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETN98994.1 - 6.7e-05 21.2 0.3 9.6e-05 20.7 0.0 1.4 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Peptidase_S66 PF02016.10 ETN98994.1 - 0.035 13.0 0.1 0.05 12.5 0.1 1.2 1 0 0 1 1 1 0 LD-carboxypeptidase DUF4221 PF13970.1 ETN98994.1 - 0.087 12.1 9.8 0.45 9.7 6.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4221) DUF2480 PF10652.4 ETN98994.1 - 0.48 9.9 3.7 0.13 11.7 0.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2480) WD40 PF00400.27 ETN98995.1 - 7.5e-34 114.4 0.3 1.2e-12 47.2 0.0 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETN98995.1 - 0.00018 20.4 0.2 0.059 12.1 0.0 2.1 1 1 1 2 2 2 2 Nup133 N terminal like Nup160 PF11715.3 ETN98995.1 - 0.0016 16.6 0.1 0.55 8.2 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF1914 PF08932.5 ETN98995.1 - 0.08 12.9 0.1 0.39 10.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1914) Peptidase_C14 PF00656.17 ETN98996.1 - 1.5e-13 51.0 0.4 1.9e-13 50.7 0.3 1.1 1 0 0 1 1 1 1 Caspase domain DUF1777 PF08648.7 ETN98997.1 - 0.00092 18.9 20.8 0.001 18.8 14.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) Corona_nucleoca PF00937.13 ETN98997.1 - 0.035 13.0 16.8 0.037 12.9 11.6 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein TBX PF12598.3 ETN98997.1 - 0.044 14.1 9.9 0.069 13.5 6.6 1.6 1 1 0 1 1 1 0 T-box transcription factor MLANA PF14991.1 ETN98997.1 - 0.11 12.4 1.4 0.51 10.3 0.9 2.0 1 1 0 1 1 1 0 Protein melan-A DUF2722 PF10846.3 ETN98997.1 - 0.86 8.5 15.5 1 8.3 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Hid1 PF12722.2 ETN98997.1 - 9.7 3.7 12.7 12 3.4 8.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein WD40 PF00400.27 ETN98998.1 - 1.9e-30 103.6 0.9 2.6e-14 52.4 0.0 2.0 2 0 0 2 2 2 2 WD domain, G-beta repeat PD40 PF07676.7 ETN98998.1 - 0.0048 16.5 0.6 0.98 9.1 0.1 2.2 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat DUF2415 PF10313.4 ETN98998.1 - 0.0095 15.5 0.0 0.23 11.1 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) Rpn3_C PF08375.6 ETN98998.1 - 0.12 12.8 0.0 13 6.3 0.0 2.1 1 1 1 2 2 2 0 Proteasome regulatory subunit C-terminal BLOC1_2 PF10046.4 ETN98999.1 - 0.0082 16.2 0.3 0.021 14.9 0.2 1.7 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 ETN98999.1 - 0.022 14.3 6.2 0.048 13.2 4.3 1.5 1 1 0 1 1 1 0 IncA protein HOOK PF05622.7 ETN98999.1 - 0.042 11.6 1.0 0.054 11.3 0.7 1.1 1 0 0 1 1 1 0 HOOK protein THOC7 PF05615.8 ETN98999.1 - 0.049 13.8 0.3 0.1 12.8 0.2 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 DUF972 PF06156.8 ETN98999.1 - 0.1 12.9 0.9 0.22 11.8 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) TSC22 PF01166.13 ETN98999.1 - 0.15 12.0 0.8 1.3 9.0 0.6 2.4 1 1 0 1 1 1 0 TSC-22/dip/bun family DivIC PF04977.10 ETN98999.1 - 0.31 10.5 2.1 1.7 8.1 0.1 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF4097 PF13349.1 ETN99000.1 - 0.04 13.4 0.2 0.043 13.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) DUF3173 PF11372.3 ETN99000.1 - 0.049 13.2 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3173) DUF500 PF04366.7 ETN99000.1 - 0.069 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF500) DUF1108 PF06531.6 ETN99000.1 - 0.097 12.8 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1108) RE_MjaI PF09568.5 ETN99001.1 - 0.011 15.3 0.1 0.013 15.0 0.1 1.0 1 0 0 1 1 1 0 MjaI restriction endonuclease NARP1 PF12569.3 ETN99002.1 - 4.6 5.8 10.7 5.2 5.7 7.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 AAA PF00004.24 ETN99004.1 - 0.0055 16.9 0.0 0.0096 16.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETN99004.1 - 0.0079 15.9 0.1 0.2 11.3 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETN99004.1 - 0.024 14.7 0.0 0.11 12.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain TIP120 PF08623.5 ETN99005.1 - 0.087 12.4 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) DUF496 PF04363.7 ETN99005.1 - 0.095 12.5 1.5 0.36 10.6 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF496) Kelch_4 PF13418.1 ETN99007.1 - 1.1e-07 31.4 0.7 0.00098 18.8 0.1 3.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETN99007.1 - 0.0004 19.8 3.4 0.028 13.9 0.7 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 ETN99007.1 - 0.0019 18.3 7.9 0.39 10.9 0.8 3.9 4 1 1 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETN99007.1 - 0.012 15.3 2.4 1.3 8.9 0.2 3.7 4 0 0 4 4 4 0 Kelch motif MIP-T3 PF10243.4 ETN99008.1 - 0.016 13.7 43.2 0.018 13.5 29.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Utp14 PF04615.8 ETN99008.1 - 0.028 12.5 43.6 0.038 12.1 30.2 1.1 1 0 0 1 1 1 0 Utp14 protein Herpes_LMP1 PF05297.6 ETN99008.1 - 0.19 10.6 2.8 0.24 10.2 1.9 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) PLRV_ORF5 PF01690.12 ETN99008.1 - 0.3 10.1 25.7 0.37 9.8 17.8 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Daxx PF03344.10 ETN99008.1 - 0.66 8.3 37.1 0.77 8.1 25.7 1.1 1 0 0 1 1 1 0 Daxx Family Ndc1_Nup PF09531.5 ETN99008.1 - 0.84 7.9 10.2 1 7.6 7.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LMBR1 PF04791.11 ETN99008.1 - 2.5 6.5 7.2 2.4 6.6 4.4 1.3 1 1 0 1 1 1 0 LMBR1-like membrane protein N6_Mtase PF02384.11 ETN99009.1 - 1e-20 74.0 0.1 1.1e-20 73.9 0.1 1.0 1 0 0 1 1 1 1 N-6 DNA Methylase UPF0020 PF01170.13 ETN99009.1 - 0.00052 19.6 0.0 0.00072 19.1 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 MTS PF05175.9 ETN99009.1 - 0.0032 16.8 0.0 0.0046 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 ETN99009.1 - 0.0097 15.9 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Eco57I PF07669.6 ETN99009.1 - 0.021 15.1 0.0 0.042 14.2 0.0 1.5 1 1 0 1 1 1 0 Eco57I restriction-modification methylase Kelch_1 PF01344.20 ETN99010.1 - 3.6e-07 29.6 0.1 7.7e-05 22.1 0.1 2.6 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 ETN99010.1 - 1.3e-05 24.8 0.1 0.00014 21.5 0.0 2.3 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETN99010.1 - 3.9e-05 23.6 0.0 0.00013 22.0 0.0 1.9 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETN99010.1 - 0.00066 19.7 2.6 0.01 15.9 0.1 3.2 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 ETN99010.1 - 0.028 14.1 0.2 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 Kelch motif Helicase_C_2 PF13307.1 ETN99012.1 - 0.03 14.2 0.1 0.075 12.9 0.1 1.6 1 0 0 1 1 1 0 Helicase C-terminal domain EamA PF00892.15 ETN99013.1 - 0.033 14.2 9.3 0.033 14.2 4.0 2.2 1 1 1 2 2 2 0 EamA-like transporter family Kei1 PF08552.6 ETN99013.1 - 0.21 11.2 2.1 0.33 10.5 0.4 1.9 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 DUF2808 PF10989.3 ETN99014.1 - 0.047 13.2 0.1 0.092 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) Phage_lambd_GpG PF06894.6 ETN99014.1 - 0.055 13.0 0.1 0.12 12.0 0.1 1.5 1 1 0 1 1 1 0 Bacteriophage lambda minor tail protein (GpG) V-ATPase_C PF03223.10 ETN99017.1 - 0.013 14.4 0.1 0.013 14.4 0.0 1.1 1 0 0 1 1 1 0 V-ATPase subunit C zf-C3HC4_2 PF13923.1 ETN99017.1 - 0.015 15.3 5.6 0.21 11.6 3.9 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1413 PF07205.6 ETN99017.1 - 0.073 12.6 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1413) Cys_knot PF00007.17 ETN99017.1 - 0.2 11.7 6.6 0.25 11.4 4.6 1.3 1 0 0 1 1 1 0 Cystine-knot domain zf-C3HC4_3 PF13920.1 ETN99018.1 - 3.8e-10 39.2 9.4 8.3e-10 38.1 6.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETN99018.1 - 7.1e-08 32.3 10.9 7.8e-08 32.2 6.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FHA PF00498.21 ETN99018.1 - 5.2e-06 26.4 0.2 1e-05 25.5 0.1 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 ETN99018.1 - 1e-05 25.2 7.6 1e-05 25.2 5.3 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 ETN99018.1 - 4.1e-05 23.1 13.0 4.2e-05 23.1 6.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETN99018.1 - 0.00021 20.9 9.4 0.00021 20.9 6.5 2.3 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 ETN99018.1 - 0.007 16.0 6.2 0.007 16.0 4.3 1.9 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.1 ETN99018.1 - 0.011 15.2 4.6 0.011 15.2 3.2 2.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 ETN99018.1 - 0.017 15.0 5.9 0.13 12.1 3.6 2.7 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 ETN99018.1 - 0.038 13.5 6.6 0.078 12.5 4.0 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF2070 PF09843.4 ETN99018.1 - 0.063 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF1510 PF07423.6 ETN99019.1 - 0.00077 18.9 2.4 0.00099 18.5 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Tom37_C PF11801.3 ETN99019.1 - 0.02 14.7 3.8 0.032 14.1 2.6 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain Raftlin PF15250.1 ETN99019.1 - 0.037 12.5 1.7 0.046 12.2 1.2 1.1 1 0 0 1 1 1 0 Raftlin CDC45 PF02724.9 ETN99019.1 - 0.12 10.3 8.9 0.16 10.0 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein PYST-C1 PF09690.5 ETN99019.1 - 0.62 9.7 11.5 1.2 8.8 8.0 1.5 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) PBP1_TM PF14812.1 ETN99019.1 - 4.5 7.6 13.3 10 6.5 9.2 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Rhabdo_ncap PF00945.13 ETN99019.1 - 5.6 5.4 8.4 7.9 4.9 5.8 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Na_Ca_ex PF01699.19 ETN99020.1 - 5.3e-11 42.2 14.7 7.8e-09 35.2 3.8 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein TRAP_alpha PF03896.11 ETN99020.1 - 0.044 12.7 0.2 0.077 11.9 0.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Cyto_ox_2 PF02322.10 ETN99020.1 - 0.05 12.7 6.6 0.041 13.0 0.5 2.1 2 0 0 2 2 2 0 Cytochrome oxidase subunit II DUF3816 PF12822.2 ETN99020.1 - 0.056 13.3 0.7 0.056 13.3 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3816) DUF872 PF05915.7 ETN99020.1 - 0.057 13.2 5.1 1.8 8.4 0.2 3.1 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF872) DUF456 PF04306.8 ETN99020.1 - 7.6 6.5 13.9 5.7 6.9 4.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF456) Kelch_6 PF13964.1 ETN99021.1 - 0.00099 19.1 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 Kelch motif Kelch_5 PF13854.1 ETN99021.1 - 0.03 14.3 0.1 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 Kelch motif GF_recep_IV PF14843.1 ETN99021.1 - 0.081 12.5 0.1 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 Growth factor receptor domain IV Ins_beta PF03488.9 ETN99022.1 - 1.3 8.9 4.3 2.5 7.9 0.8 2.3 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type Daxx PF03344.10 ETN99025.1 - 8.3 4.7 10.0 8.7 4.6 6.9 1.0 1 0 0 1 1 1 0 Daxx Family TehB PF03848.9 ETN99026.1 - 0.024 13.8 0.9 0.036 13.2 0.1 1.6 2 0 0 2 2 2 0 Tellurite resistance protein TehB LMBR1 PF04791.11 ETN99026.1 - 0.18 10.3 1.5 0.22 10.0 1.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein HTH_44 PF14641.1 ETN99027.1 - 0.031 14.2 0.2 0.06 13.3 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix DNA-binding domain of SPT6 W2 PF02020.13 ETN99027.1 - 0.044 13.7 0.4 0.1 12.5 0.2 1.7 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon DUF708 PF05341.6 ETN99027.1 - 1.8 8.4 4.9 11 5.8 0.1 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF708) SAM_1 PF00536.25 ETN99028.1 - 6.4e-06 26.2 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETN99028.1 - 4.5e-05 23.2 0.0 0.00011 21.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Macoilin PF09726.4 ETN99028.1 - 7.3 4.7 13.2 8.7 4.4 9.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Y_phosphatase2 PF03162.8 ETN99029.1 - 3.8e-48 162.9 0.0 8.5e-48 161.8 0.0 1.5 1 1 1 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 ETN99029.1 - 0.00021 21.5 0.3 0.00071 19.8 0.0 1.9 2 1 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 ETN99029.1 - 0.00028 20.4 0.1 0.0011 18.5 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 ETN99029.1 - 0.0025 17.2 0.0 0.005 16.2 0.0 1.5 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DUF2207 PF09972.4 ETN99031.1 - 0.89 8.0 4.3 0.15 10.5 0.6 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF3524 PF12038.3 ETN99032.1 - 4.4e-16 58.8 1.4 2.9e-15 56.2 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3524) Glycos_transf_1 PF00534.15 ETN99032.1 - 9.4e-08 31.6 0.0 1.5e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 ETN99032.1 - 0.00044 20.4 0.0 0.00089 19.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Methyltransf_12 PF08242.7 ETN99033.1 - 5.9e-10 39.5 0.0 8.7e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 ETN99033.1 - 2.3e-08 33.4 0.0 3.5e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 ETN99033.1 - 4.4e-07 30.4 0.0 6.7e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 ETN99033.1 - 7.5e-07 28.8 0.0 1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_11 PF08241.7 ETN99033.1 - 8.8e-06 26.1 0.0 1.4e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETN99033.1 - 1.4e-05 24.7 0.0 1.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETN99033.1 - 6.1e-05 23.3 0.0 9.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_5 PF01795.14 ETN99033.1 - 7.2e-05 22.2 0.0 0.00011 21.5 0.0 1.3 1 0 0 1 1 1 1 MraW methylase family Methyltransf_4 PF02390.12 ETN99033.1 - 9e-05 21.6 0.0 0.00013 21.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.1 ETN99033.1 - 0.00047 19.8 0.0 0.00057 19.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETN99033.1 - 0.0026 17.5 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 ETN99033.1 - 0.017 14.6 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 ETN99033.1 - 0.027 13.4 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DOT1 PF08123.8 ETN99033.1 - 0.075 12.3 0.0 0.12 11.6 0.0 1.4 1 1 0 1 1 1 0 Histone methylation protein DOT1 MTS PF05175.9 ETN99033.1 - 0.081 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 ETN99033.1 - 0.14 12.1 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Pollen_Ole_e_I PF01190.12 ETN99035.1 - 0.076 12.8 0.1 0.28 11.0 0.0 1.8 1 1 1 2 2 2 0 Pollen proteins Ole e I like TFIIF_alpha PF05793.7 ETN99037.1 - 0.55 8.5 24.3 0.68 8.2 16.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SURF6 PF04935.7 ETN99037.1 - 1.3 8.2 19.3 1.7 7.8 13.4 1.2 1 0 0 1 1 1 0 Surfeit locus protein 6 Peptidase_S64 PF08192.6 ETN99037.1 - 4.7 5.4 17.1 4.9 5.3 11.9 1.0 1 0 0 1 1 1 0 Peptidase family S64 Nop14 PF04147.7 ETN99037.1 - 5.5 4.7 28.4 6.5 4.5 19.7 1.1 1 0 0 1 1 1 0 Nop14-like family ABC2_membrane_3 PF12698.2 ETN99037.1 - 9 5.2 11.1 10 5.0 7.7 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein BUD22 PF09073.5 ETN99037.1 - 9.1 5.2 24.6 11 4.9 17.0 1.1 1 0 0 1 1 1 0 BUD22 Rtf2 PF04641.7 ETN99037.1 - 9.9 5.2 17.9 13 4.8 12.4 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger FAM92 PF06730.6 ETN99038.1 - 0.039 13.2 1.3 0.042 13.1 0.9 1.1 1 0 0 1 1 1 0 FAM92 protein DUF2855 PF11017.3 ETN99038.1 - 0.047 12.8 0.2 0.051 12.7 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) WD40 PF00400.27 ETN99040.1 - 1.9e-20 71.9 8.1 6.5e-12 44.8 0.2 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETN99040.1 - 0.011 14.5 0.2 1.6 7.3 0.0 2.1 1 1 1 2 2 2 0 Nup133 N terminal like Nup160 PF11715.3 ETN99040.1 - 0.019 13.1 1.3 0.26 9.3 0.0 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 ETN99040.1 - 0.027 13.2 0.0 0.032 13.0 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region Hira PF07569.6 ETN99040.1 - 0.067 12.4 0.3 0.2 10.8 0.2 1.7 1 1 0 1 1 1 0 TUP1-like enhancer of split zf-CCHC PF00098.18 ETN99041.1 - 0.5 10.3 6.3 0.84 9.6 4.4 1.4 1 0 0 1 1 1 0 Zinc knuckle COesterase PF00135.23 ETN99041.1 - 1.2 7.8 5.4 1.4 7.5 3.8 1.0 1 0 0 1 1 1 0 Carboxylesterase family NP1-WLL PF11733.3 ETN99041.1 - 2.1 8.6 6.5 1.9 8.8 1.2 2.7 2 1 0 2 2 2 0 Non-capsid protein NP1 Presenilin PF01080.12 ETN99041.1 - 8.5 5.0 6.0 9.9 4.8 4.1 1.2 1 0 0 1 1 1 0 Presenilin Cobl PF09469.5 ETN99043.1 - 1.7 8.6 6.0 0.49 10.3 2.0 1.6 2 0 0 2 2 2 0 Cordon-bleu ubiquitin-like domain YesK PF14150.1 ETN99044.1 - 0.16 12.0 1.1 0.28 11.3 0.7 1.3 1 0 0 1 1 1 0 YesK-like protein DUF4653 PF15546.1 ETN99045.1 - 0.015 14.6 1.0 0.019 14.2 0.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4653) Serinc PF03348.10 ETN99045.1 - 0.079 11.6 2.3 0.11 11.2 1.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Muted PF14942.1 ETN99045.1 - 8.6 6.2 13.4 0.2 11.5 2.0 2.1 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein ODV-E18 PF10717.4 ETN99047.1 - 2.3 7.6 6.5 0.49 9.8 0.1 2.8 3 1 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 Lig_chan PF00060.21 ETN99047.1 - 8.9 6.0 7.7 0.32 10.6 0.7 1.9 2 1 0 2 2 2 0 Ligand-gated ion channel Kelch_1 PF01344.20 ETN99048.1 - 9e-11 41.1 4.6 2.8e-05 23.5 0.2 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETN99048.1 - 1.2e-06 28.2 0.2 0.024 14.3 0.0 3.4 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETN99048.1 - 5e-06 26.4 4.6 0.021 15.0 0.1 3.9 3 1 1 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETN99048.1 - 1.1e-05 25.0 0.5 0.095 12.5 0.1 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 ETN99048.1 - 0.002 18.0 2.0 0.85 9.6 0.0 3.5 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETN99048.1 - 0.035 14.2 0.0 11 6.3 0.0 3.1 3 0 0 3 3 3 0 Galactose oxidase, central domain RepA_N PF06970.6 ETN99048.1 - 0.15 11.8 2.6 2.3 8.0 0.1 3.1 2 1 0 2 2 2 0 Replication initiator protein A (RepA) N-terminus CFTR_R PF14396.1 ETN99049.1 - 0.082 12.2 0.1 0.2 10.9 0.1 1.6 1 1 1 2 2 2 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain WD40 PF00400.27 ETN99050.1 - 2.8e-23 80.8 0.2 1.8e-09 37.1 0.1 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat PQQ_2 PF13360.1 ETN99050.1 - 0.002 17.6 0.0 0.0026 17.2 0.0 1.2 1 0 0 1 1 1 1 PQQ-like domain Nucleoporin_N PF08801.6 ETN99050.1 - 0.018 13.8 0.1 0.23 10.1 0.0 1.9 1 1 1 2 2 2 0 Nup133 N terminal like RasGEF PF00617.14 ETN99053.1 - 6.4e-33 114.0 1.4 1.2e-32 113.1 1.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 ETN99053.1 - 4.6e-12 45.9 0.3 4.6e-12 45.9 0.2 2.7 2 0 0 2 2 2 1 RasGEF N-terminal motif DUF448 PF04296.8 ETN99054.1 - 0.0068 16.0 2.8 0.024 14.2 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF448) DZR PF12773.2 ETN99054.1 - 0.095 12.5 7.6 1.4 8.8 1.2 2.3 2 0 0 2 2 2 0 Double zinc ribbon RVT_1 PF00078.22 ETN99055.1 - 0.00021 20.7 0.1 0.0003 20.2 0.0 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HrpB7 PF09486.5 ETN99056.1 - 0.012 15.5 0.8 0.017 15.0 0.6 1.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Mnd1 PF03962.10 ETN99056.1 - 0.039 13.6 4.9 0.051 13.2 3.4 1.1 1 0 0 1 1 1 0 Mnd1 family Atg14 PF10186.4 ETN99056.1 - 0.1 11.5 3.5 0.12 11.2 2.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF106 PF01956.11 ETN99056.1 - 0.1 12.1 2.6 0.16 11.5 1.8 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF106 Pox_A_type_inc PF04508.7 ETN99056.1 - 4.3 7.3 7.6 3.2 7.7 0.6 2.7 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat Thioredoxin_6 PF13848.1 ETN99059.1 - 0.046 13.5 0.9 0.058 13.1 0.2 1.5 2 0 0 2 2 2 0 Thioredoxin-like domain HSP90 PF00183.13 ETN99061.1 - 2.2e-11 42.8 10.8 3.3e-05 22.4 1.3 3.1 2 1 1 3 3 3 3 Hsp90 protein DIL PF01843.14 ETN99061.1 - 0.031 14.1 0.4 0.24 11.2 0.0 2.4 2 1 0 2 2 2 0 DIL domain CUB PF00431.15 ETN99062.1 - 0.03 14.3 1.0 0.04 13.9 0.7 1.3 1 0 0 1 1 1 0 CUB domain HMG_CoA_synt_N PF01154.12 ETN99062.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase N terminal PDZ PF00595.19 ETN99063.1 - 0.00018 21.6 0.0 0.00044 20.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 ETN99063.1 - 0.00027 20.7 0.3 0.0011 18.8 0.0 2.1 2 1 0 2 2 2 1 PDZ domain SAM_1 PF00536.25 ETN99063.1 - 0.00061 19.9 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETN99063.1 - 0.00071 19.3 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CENP-B_dimeris PF09026.5 ETN99065.1 - 0.0075 16.4 15.2 0.034 14.3 10.5 1.9 2 0 0 2 2 2 1 Centromere protein B dimerisation domain RXT2_N PF08595.6 ETN99065.1 - 0.019 14.7 7.4 0.019 14.7 5.1 1.7 2 0 0 2 2 2 0 RXT2-like, N-terminal Nop14 PF04147.7 ETN99065.1 - 0.096 10.5 14.2 0.14 10.1 9.8 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 ETN99065.1 - 0.1 11.8 11.3 0.17 11.1 7.8 1.3 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 ETN99065.1 - 0.76 7.7 7.2 1.2 7.1 5.0 1.2 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.11 ETN99065.1 - 0.81 8.6 8.4 1.4 7.8 5.8 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Prothymosin PF03247.9 ETN99065.1 - 0.87 9.7 26.3 1.6 8.8 18.2 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family PI3K_1B_p101 PF10486.4 ETN99065.1 - 1.6 6.1 4.1 2.5 5.5 2.9 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Nucleoplasmin PF03066.10 ETN99065.1 - 1.6 8.2 19.0 3.4 7.1 13.2 1.5 1 0 0 1 1 1 0 Nucleoplasmin COPI_C PF06957.6 ETN99065.1 - 1.8 7.0 4.4 2.5 6.5 3.0 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Daxx PF03344.10 ETN99065.1 - 1.9 6.8 21.2 0.015 13.7 8.9 1.6 2 0 0 2 2 2 0 Daxx Family BSP_II PF05432.6 ETN99065.1 - 5.2 6.2 21.2 0.45 9.7 11.2 1.8 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DUF2890 PF11081.3 ETN99065.1 - 6.4 6.7 15.2 0.28 11.2 5.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) PPP4R2 PF09184.6 ETN99065.1 - 6.8 6.1 21.3 0.45 10.0 11.3 1.5 2 0 0 2 2 2 0 PPP4R2 Pkinase PF00069.20 ETN99068.1 - 3.9e-20 72.1 0.3 1.3e-19 70.3 0.2 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETN99068.1 - 1.3e-10 40.8 0.1 2e-10 40.1 0.1 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETN99068.1 - 0.00032 19.8 0.0 0.00053 19.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-TRAF PF02176.13 ETN99070.1 - 7.4e-05 23.0 3.4 0.00014 22.1 1.4 2.2 2 1 0 2 2 2 1 TRAF-type zinc finger DUF4375 PF14300.1 ETN99070.1 - 0.0074 16.2 0.3 0.0091 15.9 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4375) zf-H2C2_5 PF13909.1 ETN99070.1 - 4.2 7.7 5.5 52 4.3 0.0 3.8 3 1 0 3 3 3 0 C2H2-type zinc-finger domain Kelch_4 PF13418.1 ETN99073.1 - 2.7e-08 33.4 0.1 7.3e-06 25.6 0.0 2.3 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETN99073.1 - 6.2e-08 32.0 0.4 1.5e-05 24.3 0.1 2.2 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.10 ETN99073.1 - 4.2e-07 29.4 0.4 0.00019 21.0 0.2 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.1 ETN99073.1 - 1.7e-05 24.7 1.0 0.0047 17.0 0.2 2.3 1 1 1 2 2 2 2 Kelch motif Kelch_3 PF13415.1 ETN99073.1 - 0.0086 16.2 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETN99073.1 - 0.078 12.9 0.2 1.1 9.3 0.3 2.3 2 0 0 2 2 2 0 Kelch motif DUF3964 PF13107.1 ETN99073.1 - 0.1 12.8 0.1 0.29 11.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3964) TatD_DNase PF01026.16 ETN99074.1 - 6.3e-25 87.8 0.0 6.9e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase ART PF01129.13 ETN99075.1 - 0.0017 17.4 0.4 0.0055 15.8 0.0 1.9 2 0 0 2 2 2 1 NAD:arginine ADP-ribosyltransferase UBA_e1_C PF09358.5 ETN99075.1 - 0.02 15.0 0.4 0.1 12.7 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-activating enzyme e1 C-terminal domain DUF4321 PF14209.1 ETN99075.1 - 0.11 12.2 0.1 0.25 11.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4321) DUF2521 PF10730.4 ETN99076.1 - 0.015 15.1 0.9 0.028 14.2 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2521) WD40 PF00400.27 ETN99076.1 - 0.1 12.4 0.8 0.83 9.6 0.6 2.3 1 1 0 1 1 1 0 WD domain, G-beta repeat WD40 PF00400.27 ETN99077.1 - 1e-39 133.0 20.9 1.5e-12 46.8 0.0 4.7 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETN99077.1 - 1.4e-10 39.9 1.1 0.028 12.5 0.1 4.0 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETN99077.1 - 0.0036 16.1 1.1 3.8 6.1 0.0 3.2 1 1 3 4 4 4 2 Nup133 N terminal like DUF1264 PF06884.6 ETN99077.1 - 0.035 13.5 1.3 13 5.1 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1264) PSI PF01437.20 ETN99077.1 - 2.2 8.4 9.2 0.14 12.3 2.6 2.0 2 0 0 2 2 2 0 Plexin repeat zf-TRAF PF02176.13 ETN99078.1 - 3.9e-07 30.3 6.1 7.7e-07 29.3 3.9 1.8 1 1 0 1 1 1 1 TRAF-type zinc finger UPF0449 PF15136.1 ETN99078.1 - 8.3 6.6 12.0 7.4 6.8 3.0 2.7 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 DUF663 PF04950.7 ETN99080.1 - 0.038 12.9 0.2 0.041 12.8 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF663) Tetraspannin PF00335.15 ETN99080.1 - 0.065 12.5 0.8 0.078 12.2 0.5 1.2 1 0 0 1 1 1 0 Tetraspanin family TPR_19 PF14559.1 ETN99082.1 - 8.9e-06 25.9 0.6 0.00013 22.2 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETN99082.1 - 0.00098 18.6 1.2 0.04 13.5 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETN99082.1 - 0.0077 16.7 2.5 0.26 12.0 0.1 4.1 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETN99082.1 - 0.011 15.6 9.2 0.055 13.4 1.6 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 ETN99082.1 - 0.018 14.7 3.4 0.39 10.3 0.5 2.8 2 0 0 2 2 2 0 TPR repeat TPR_16 PF13432.1 ETN99082.1 - 0.025 15.2 6.9 0.33 11.6 0.8 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETN99082.1 - 0.033 14.1 4.3 0.079 12.9 1.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETN99082.1 - 0.038 14.4 4.8 16 6.2 0.1 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 ETN99082.1 - 0.32 11.1 5.8 0.33 11.0 2.5 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Trypan_PARP PF05887.6 ETN99082.1 - 0.73 9.6 22.6 1.4 8.7 15.7 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) UPF0029 PF01205.14 ETN99084.1 - 3.9e-30 103.7 0.1 8.5e-30 102.6 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 ETN99084.1 - 6.9e-09 35.6 0.6 2.1e-08 34.0 0.4 1.8 1 0 0 1 1 1 1 RWD domain ATG19_autophagy PF12744.2 ETN99084.1 - 0.0039 16.4 0.0 0.0086 15.3 0.0 1.5 1 0 0 1 1 1 1 Autophagy protein Atg19, Atg8-binding T_Ag_DNA_bind PF02217.11 ETN99085.1 - 0.089 13.1 0.0 0.12 12.7 0.0 1.3 1 1 0 1 1 1 0 Origin of replication binding protein Chorein_N PF12624.2 ETN99085.1 - 0.29 10.6 3.8 0.35 10.4 2.0 1.5 1 1 1 2 2 2 0 N-terminal region of Chorein, a TM vesicle-mediated sorter FAM60A PF15396.1 ETN99086.1 - 0.63 9.7 13.6 0.82 9.3 9.4 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF808 PF05661.7 ETN99086.1 - 1.9 7.2 3.8 2.5 6.8 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF808) DUF2252 PF10009.4 ETN99086.1 - 2 7.2 5.7 2.9 6.7 4.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) GAGA_bind PF06217.7 ETN99086.1 - 6.4 6.6 14.0 8.3 6.2 9.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family N6_N4_Mtase PF01555.13 ETN99086.1 - 7.7 5.9 19.9 9.2 5.6 13.2 1.6 1 1 1 2 2 2 0 DNA methylase Neur_chan_memb PF02932.11 ETN99086.1 - 9.2 6.0 7.2 11 5.8 5.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SK_channel PF03530.9 ETN99087.1 - 0.019 14.8 0.1 0.028 14.2 0.1 1.3 1 0 0 1 1 1 0 Calcium-activated SK potassium channel Cys_rich_VLP PF14194.1 ETN99088.1 - 0.04 13.6 0.4 0.096 12.4 0.3 1.6 1 0 0 1 1 1 0 Cysteine-rich VLP CutA1 PF03091.10 ETN99088.1 - 0.54 9.9 3.4 3 7.5 1.0 2.1 1 1 1 2 2 2 0 CutA1 divalent ion tolerance protein Inos-1-P_synth PF01658.12 ETN99089.1 - 0.8 9.5 7.2 1.1 9.1 0.8 2.4 1 1 0 2 2 2 0 Myo-inositol-1-phosphate synthase DsrD PF08679.6 ETN99089.1 - 7.9 6.5 7.2 4.6 7.3 0.1 3.0 2 1 2 4 4 4 0 Dissimilatory sulfite reductase D (DsrD) SIP1 PF04938.7 ETN99091.1 - 0.069 12.4 8.6 0.09 12.1 5.9 1.3 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) Protocadherin PF08374.6 ETN99091.1 - 1.2 8.7 0.0 1.2 8.7 0.0 2.6 1 1 1 2 2 2 0 Protocadherin LMBR1 PF04791.11 ETN99091.1 - 1.9 6.9 7.0 2.4 6.6 4.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein AAA_21 PF13304.1 ETN99091.1 - 6.6 6.5 11.6 8.7 6.2 8.1 1.1 1 0 0 1 1 1 0 AAA domain Neur_chan_memb PF02932.11 ETN99091.1 - 8.5 6.1 9.6 13 5.5 6.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SRC-1 PF08832.5 ETN99092.1 - 7.3 7.4 7.0 0.77 10.5 0.4 2.3 2 1 0 2 2 2 0 Steroid receptor coactivator TPR_12 PF13424.1 ETN99095.1 - 1e-19 70.2 6.4 8e-14 51.3 1.6 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETN99095.1 - 1.3e-08 34.3 9.3 2.8e-07 30.0 2.1 2.0 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETN99095.1 - 9.5e-08 31.3 8.4 0.00041 19.8 0.3 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETN99095.1 - 6.6e-07 28.6 0.4 0.0041 16.8 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETN99095.1 - 2.6e-05 23.9 0.1 0.02 14.8 0.0 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETN99095.1 - 0.00077 19.0 13.0 0.003 17.2 0.2 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETN99095.1 - 0.0098 15.7 5.2 0.088 12.7 0.3 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.13 ETN99095.1 - 1.2 9.0 4.8 13 5.7 0.1 2.9 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain DUF4201 PF13870.1 ETN99098.1 - 1.2 8.4 10.5 0.11 11.9 1.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Rho_Binding PF08912.6 ETN99098.1 - 7.7 6.8 9.9 3.5 7.9 3.0 2.2 2 0 0 2 2 2 0 Rho Binding FeS PF04060.8 ETN99099.1 - 0.09 12.3 2.5 3.5 7.2 0.2 2.5 2 0 0 2 2 2 0 Putative Fe-S cluster TPR_12 PF13424.1 ETN99100.1 - 8.3e-35 118.5 14.0 5e-14 51.9 0.1 3.6 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETN99100.1 - 5.7e-15 54.2 9.3 1.8e-07 30.4 0.1 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETN99100.1 - 5.2e-14 51.6 13.4 1.6e-05 24.4 0.5 3.5 1 1 1 3 3 3 3 TPR repeat TPR_7 PF13176.1 ETN99100.1 - 1.6e-11 43.0 1.5 0.0029 17.2 0.0 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETN99100.1 - 3.7e-11 42.0 8.4 0.00025 20.7 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETN99100.1 - 3.7e-10 38.8 8.4 0.00036 20.1 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETN99100.1 - 8e-10 38.3 0.1 5.8e-06 26.0 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETN99100.1 - 5.8e-05 23.3 0.0 0.37 11.5 0.0 4.2 5 0 0 5 5 3 1 Tetratricopeptide repeat Apc3 PF12895.2 ETN99100.1 - 0.0018 18.3 5.5 0.0065 16.5 0.6 2.7 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETN99100.1 - 0.0028 18.0 0.1 1.5 9.4 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 ETN99100.1 - 0.093 12.6 3.5 1.1 9.1 0.0 4.0 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain PPR PF01535.15 ETN99100.1 - 0.12 12.4 4.1 6.7 6.9 0.0 4.4 5 0 0 5 5 5 0 PPR repeat Sel1 PF08238.7 ETN99100.1 - 0.12 13.0 1.2 18 6.1 0.0 3.4 3 0 0 3 3 3 0 Sel1 repeat TPR_17 PF13431.1 ETN99100.1 - 0.44 10.8 4.4 16 6.0 0.1 3.8 4 1 0 4 4 3 0 Tetratricopeptide repeat WD40 PF00400.27 ETN99101.1 - 4.9e-80 260.8 18.6 2.8e-13 49.2 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETN99101.1 - 3.3e-08 32.1 4.6 0.27 9.2 0.1 4.5 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETN99101.1 - 1.3e-05 23.6 0.8 0.0084 14.4 0.1 2.9 1 1 3 4 4 3 3 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETN99101.1 - 0.00069 19.1 1.7 0.056 12.8 0.6 3.2 1 1 1 2 2 2 2 PQQ-like domain PD40 PF07676.7 ETN99101.1 - 0.0017 17.9 5.5 31 4.3 0.0 5.8 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Gmad1 PF10647.4 ETN99101.1 - 0.018 14.4 0.0 0.093 12.1 0.0 2.4 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain Mid2 PF04478.7 ETN99101.1 - 0.061 12.7 6.0 3.7 6.9 0.0 3.9 2 1 2 4 4 4 0 Mid2 like cell wall stress sensor DUF727 PF05303.7 ETN99101.1 - 0.1 12.3 0.3 2.3 8.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF727) Proteasome_A_N PF10584.4 ETN99101.1 - 1.1 8.6 6.2 3.3 7.1 0.0 3.6 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 ETN99102.1 - 8e-45 149.1 26.0 2.5e-10 39.8 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETN99102.1 - 4.9e-08 31.5 4.0 0.0029 15.7 0.2 4.1 2 1 1 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETN99102.1 - 0.0016 17.2 7.5 0.26 9.9 0.0 3.5 3 1 0 3 3 3 2 Nup133 N terminal like DUF506 PF04720.7 ETN99102.1 - 0.039 13.5 0.6 0.12 11.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF506) DUF4014 PF13198.1 ETN99103.1 - 0.03 14.7 2.8 0.062 13.7 1.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4014) NACHT PF05729.7 ETN99103.1 - 0.093 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Peptidase_M15 PF01427.12 ETN99105.1 - 0.047 13.3 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 D-ala-D-ala dipeptidase Ank_2 PF12796.2 ETN99106.1 - 3.1e-10 40.2 0.0 5.7e-10 39.4 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETN99106.1 - 2.5e-08 33.3 0.0 2e-05 24.1 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 ETN99106.1 - 1.6e-07 31.6 0.0 4e-06 27.2 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETN99106.1 - 4.9e-05 23.4 0.1 0.00096 19.3 0.0 2.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETN99106.1 - 5.3e-05 23.0 0.0 0.082 13.1 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Pribosyltran PF00156.22 ETN99106.1 - 0.13 12.0 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain Apis_Csd PF11671.3 ETN99107.1 - 0.00087 19.1 4.9 0.0011 18.7 3.4 1.1 1 0 0 1 1 1 1 Complementary sex determiner protein PBP1_TM PF14812.1 ETN99107.1 - 0.012 15.9 12.6 0.015 15.5 8.7 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2413 PF10310.4 ETN99107.1 - 0.086 11.6 8.2 0.085 11.6 5.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) RXT2_N PF08595.6 ETN99107.1 - 0.15 11.8 8.1 0.19 11.5 5.6 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Pox_Ag35 PF03286.9 ETN99107.1 - 0.49 9.8 20.0 0.64 9.5 13.9 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NPR3 PF03666.8 ETN99107.1 - 0.58 8.6 9.7 0.62 8.5 6.7 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 EIAV_GP90 PF00971.13 ETN99107.1 - 0.6 8.5 4.3 0.38 9.1 2.3 1.2 1 1 0 1 1 1 0 EIAV coat protein, gp90 Folate_carrier PF01770.13 ETN99107.1 - 0.71 8.3 4.5 0.83 8.0 3.1 1.0 1 0 0 1 1 1 0 Reduced folate carrier DUF3464 PF11947.3 ETN99107.1 - 0.91 8.9 5.2 1.2 8.6 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) CDC45 PF02724.9 ETN99107.1 - 3.6 5.4 11.2 4.3 5.2 7.8 1.1 1 0 0 1 1 1 0 CDC45-like protein NARP1 PF12569.3 ETN99107.1 - 5.5 5.6 13.8 5.5 5.6 9.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Herpes_UL21 PF03252.8 ETN99108.1 - 0.077 11.4 0.1 0.088 11.2 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL21 DUF3796 PF12676.2 ETN99108.1 - 1.3 9.2 7.8 1.3 9.2 2.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) Hemocyanin_C PF03723.9 ETN99110.1 - 0.0031 16.6 0.8 0.0038 16.3 0.6 1.1 1 0 0 1 1 1 1 Hemocyanin, ig-like domain FISNA PF14484.1 ETN99110.1 - 0.036 14.0 1.0 0.077 12.9 0.3 1.9 2 1 0 2 2 2 0 Fish-specific NACHT associated domain TPR_8 PF13181.1 ETN99111.1 - 8.4e-06 25.2 0.3 0.00013 21.4 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETN99111.1 - 1.4e-05 24.9 0.1 0.011 15.6 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETN99111.1 - 0.00012 21.7 0.1 0.12 12.3 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETN99111.1 - 0.00045 19.8 0.1 0.00091 18.8 0.1 1.5 1 1 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 ETN99111.1 - 0.00049 19.6 0.2 0.25 11.0 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETN99111.1 - 0.0047 17.2 0.0 0.0097 16.2 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETN99111.1 - 0.012 16.1 0.0 0.22 12.2 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 ETN99111.1 - 0.079 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETN99111.1 - 0.13 12.9 0.0 0.49 11.1 0.0 1.8 1 1 1 2 2 2 0 Tetratricopeptide repeat eIF-3c_N PF05470.7 ETN99111.1 - 0.19 9.7 13.0 0.19 9.7 9.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Hid1 PF12722.2 ETN99111.1 - 2.2 5.8 11.1 2 5.9 7.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Astro_capsid PF03115.9 ETN99111.1 - 2.2 6.4 9.5 2.7 6.1 6.6 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Zip PF02535.17 ETN99111.1 - 2.4 7.0 8.0 3 6.7 5.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter GUCT PF08152.7 ETN99116.1 - 0.078 12.9 0.1 0.28 11.1 0.0 2.0 2 1 1 3 3 3 0 GUCT (NUC152) domain WD40 PF00400.27 ETN99117.1 - 9.4e-30 101.4 0.1 1.2e-09 37.6 0.0 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat eIF2A PF08662.6 ETN99117.1 - 2.8e-05 23.9 0.1 3.9e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETN99117.1 - 0.0003 19.0 0.7 0.22 9.5 0.0 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETN99117.1 - 0.00042 19.1 0.5 0.25 10.0 0.3 2.6 1 1 1 2 2 2 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETN99117.1 - 0.0063 14.8 0.1 0.01 14.1 0.0 1.4 1 1 0 1 1 1 1 Cytochrome D1 heme domain Nbas_N PF15492.1 ETN99117.1 - 0.019 14.1 0.0 0.23 10.5 0.0 2.2 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Ricin_B_lectin PF00652.17 ETN99117.1 - 0.021 14.8 0.1 0.055 13.5 0.0 1.6 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain CRT10 PF08728.5 ETN99117.1 - 0.027 12.4 0.1 0.033 12.1 0.1 1.1 1 0 0 1 1 1 0 CRT10 PD40 PF07676.7 ETN99117.1 - 0.1 12.2 0.3 1.7 8.4 0.0 2.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 ETN99117.1 - 1.7 8.0 4.1 16 4.8 0.1 3.2 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Baculo_p24 PF05073.7 ETN99118.1 - 0.13 11.7 4.0 0.21 11.1 2.8 1.2 1 0 0 1 1 1 0 Baculovirus P24 capsid protein Col_cuticle_N PF01484.12 ETN99118.1 - 0.15 11.7 0.7 0.22 11.2 0.0 1.6 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain Baculo_PEP_C PF04513.7 ETN99118.1 - 0.19 11.5 0.5 0.28 11.0 0.3 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CobU PF02283.11 ETN99118.1 - 1.2 8.4 4.8 0.3 10.5 1.2 1.5 1 1 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase TH1 PF04858.8 ETN99119.1 - 9.4e-09 33.9 2.2 1.3e-08 33.5 1.5 1.1 1 0 0 1 1 1 1 TH1 protein Porphobil_deam PF01379.15 ETN99120.1 - 0.014 14.2 1.7 0.047 12.6 0.2 2.2 2 0 0 2 2 2 0 Porphobilinogen deaminase, dipyromethane cofactor binding domain CK2S PF15011.1 ETN99120.1 - 0.083 12.6 1.4 2.5 7.8 0.1 2.5 2 0 0 2 2 2 0 Casein Kinase 2 substrate EIF_2_alpha PF07541.7 ETN99120.1 - 0.79 9.4 5.6 2.9 7.6 0.1 3.3 3 1 0 3 3 3 0 Eukaryotic translation initiation factor 2 alpha subunit E1-E2_ATPase PF00122.15 ETN99121.1 - 2.6e-12 46.2 0.1 9.1e-12 44.5 0.1 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 ETN99121.1 - 0.0005 20.5 0.2 0.00066 20.1 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETN99121.1 - 0.032 14.3 0.0 0.052 13.7 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase UBA_e1_C PF09358.5 ETN99122.1 - 0.071 13.2 0.5 0.14 12.3 0.1 1.6 2 0 0 2 2 2 0 Ubiquitin-activating enzyme e1 C-terminal domain Kelch_1 PF01344.20 ETN99123.1 - 1.9e-10 40.0 1.2 3.3e-05 23.3 0.1 4.0 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 ETN99123.1 - 3.7e-08 33.2 5.3 0.00044 20.3 0.1 4.7 4 2 1 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETN99123.1 - 2e-07 30.6 0.3 6.4e-05 22.6 0.0 4.0 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETN99123.1 - 5.7e-07 29.5 0.1 7.8e-05 22.7 0.0 3.3 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETN99123.1 - 0.0011 18.6 0.1 0.16 11.8 0.1 2.8 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.1 ETN99123.1 - 0.002 18.0 3.9 0.0046 16.8 0.1 3.2 5 0 0 5 5 5 1 Kelch motif Phage_lysis PF03245.8 ETN99124.1 - 0.00014 21.8 0.1 0.00016 21.6 0.1 1.2 1 0 0 1 1 1 1 Bacteriophage Rz lysis protein TMF_TATA_bd PF12325.3 ETN99124.1 - 0.0022 17.7 4.8 0.0085 15.8 0.8 2.1 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding ATG16 PF08614.6 ETN99124.1 - 0.003 17.4 1.6 0.003 17.4 1.1 1.5 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) V_ATPase_I PF01496.14 ETN99124.1 - 0.0082 14.0 0.9 0.0095 13.8 0.6 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Gp58 PF07902.6 ETN99124.1 - 0.011 13.9 0.3 0.016 13.4 0.1 1.2 1 1 0 1 1 1 0 gp58-like protein Myosin_tail_1 PF01576.14 ETN99124.1 - 0.031 12.0 1.2 0.042 11.5 0.8 1.1 1 0 0 1 1 1 0 Myosin tail DUF948 PF06103.6 ETN99124.1 - 0.042 13.6 1.0 0.081 12.7 0.3 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Tup_N PF08581.5 ETN99124.1 - 0.043 14.0 4.6 5.3 7.2 0.3 3.1 2 1 1 3 3 3 0 Tup N-terminal DUF972 PF06156.8 ETN99124.1 - 0.065 13.5 2.4 0.13 12.5 1.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Reo_sigmaC PF04582.7 ETN99124.1 - 0.065 12.4 0.3 0.07 12.2 0.2 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein ApoLp-III PF07464.6 ETN99124.1 - 0.074 13.0 0.8 0.13 12.3 0.6 1.5 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Phage_GP20 PF06810.6 ETN99124.1 - 0.086 12.2 3.7 0.05 13.0 0.7 1.8 2 0 0 2 2 2 0 Phage minor structural protein GP20 DUF1319 PF07028.6 ETN99124.1 - 0.096 12.8 1.8 0.67 10.1 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) DMPK_coil PF08826.5 ETN99124.1 - 0.11 12.4 1.3 0.29 11.0 0.9 1.8 1 1 0 1 1 1 0 DMPK coiled coil domain like PCNA_C PF02747.10 ETN99124.1 - 0.12 12.3 0.2 0.18 11.7 0.1 1.3 1 1 0 1 1 1 0 Proliferating cell nuclear antigen, C-terminal domain Kinesin-relat_1 PF12711.2 ETN99124.1 - 0.12 12.7 0.4 0.12 12.7 0.3 1.9 3 0 0 3 3 1 0 Kinesin motor Spc7 PF08317.6 ETN99124.1 - 0.13 10.9 5.1 0.083 11.5 2.6 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein Laminin_II PF06009.7 ETN99124.1 - 0.14 11.8 4.3 0.057 13.1 1.2 1.6 2 0 0 2 2 2 0 Laminin Domain II Laminin_I PF06008.9 ETN99124.1 - 0.16 11.2 3.5 0.23 10.7 2.4 1.4 1 1 0 1 1 1 0 Laminin Domain I HAUS-augmin3 PF14932.1 ETN99124.1 - 0.17 11.0 2.8 0.2 10.8 1.8 1.3 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 EzrA PF06160.7 ETN99124.1 - 0.2 9.8 4.8 0.086 11.0 0.8 1.8 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA TMF_DNA_bd PF12329.3 ETN99124.1 - 0.2 11.4 9.5 0.21 11.3 3.4 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding His_kinase PF06580.8 ETN99124.1 - 0.23 11.4 2.9 1.6 8.6 0.4 2.1 2 0 0 2 2 2 0 Histidine kinase Spectrin PF00435.16 ETN99124.1 - 0.28 11.4 2.2 0.49 10.6 0.7 1.8 1 1 0 2 2 2 0 Spectrin repeat Fib_alpha PF08702.5 ETN99124.1 - 1.2 9.2 6.6 0.56 10.3 1.3 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DivIC PF04977.10 ETN99124.1 - 1.5 8.3 6.3 0.48 9.9 1.0 2.4 2 1 1 3 3 3 0 Septum formation initiator Snapin_Pallidin PF14712.1 ETN99124.1 - 1.8 8.9 5.9 0.63 10.3 1.9 1.9 2 1 0 2 2 2 0 Snapin/Pallidin FlaC_arch PF05377.6 ETN99124.1 - 3.5 7.5 8.6 3.6 7.5 1.4 3.2 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) DUF4094 PF13334.1 ETN99125.1 - 0.031 14.6 5.3 0.031 14.6 3.7 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) Med9 PF07544.8 ETN99125.1 - 0.053 13.2 6.5 0.28 10.9 4.5 2.3 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 TMEM51 PF15345.1 ETN99125.1 - 0.07 12.8 1.9 0.15 11.7 1.3 1.5 1 0 0 1 1 1 0 Transmembrane protein 51 DUF1743 PF08489.6 ETN99125.1 - 0.095 12.4 0.5 0.26 11.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1743) TSC22 PF01166.13 ETN99125.1 - 0.13 12.2 2.7 0.16 11.9 0.2 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF3573 PF12097.3 ETN99125.1 - 2.7 6.5 7.9 0.16 10.5 2.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) MAS20 PF02064.10 ETN99125.1 - 3.6 7.5 6.8 0.5 10.2 0.6 2.3 2 0 0 2 2 2 0 MAS20 protein import receptor Imm36 PF15597.1 ETN99127.1 - 0.052 13.7 0.2 0.086 12.9 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 36 DUF1699 PF08004.6 ETN99127.1 - 0.074 12.5 0.3 0.14 11.7 0.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1699) Cpn60_TCP1 PF00118.19 ETN99128.1 - 1.9e-22 79.5 0.0 2e-22 79.5 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family WD40 PF00400.27 ETN99131.1 - 1.4e-202 649.2 48.9 4e-14 51.8 0.0 15.9 16 0 0 16 16 16 15 WD domain, G-beta repeat PQQ_2 PF13360.1 ETN99131.1 - 6e-26 91.3 18.4 5.8e-07 29.2 0.2 6.8 1 1 7 8 8 8 8 PQQ-like domain DUF1258 PF06869.7 ETN99131.1 - 6.3e-15 54.9 7.4 1.8 7.5 0.1 10.5 2 2 7 10 10 10 7 Protein of unknown function (DUF1258) PD40 PF07676.7 ETN99131.1 - 1.9e-10 40.1 31.3 23 4.7 0.1 14.3 15 0 0 15 15 15 0 WD40-like Beta Propeller Repeat Gmad1 PF10647.4 ETN99131.1 - 2.3e-10 40.3 10.4 0.011 15.0 0.4 7.6 1 1 4 5 5 5 4 Lipoprotein LpqB beta-propeller domain Cytochrom_D1 PF02239.11 ETN99131.1 - 6.7e-10 37.8 10.7 0.085 11.1 0.0 6.7 1 1 4 7 7 7 6 Cytochrome D1 heme domain AMIN PF11741.3 ETN99131.1 - 0.00011 22.0 7.1 0.14 12.1 0.1 6.7 3 1 5 10 10 10 1 AMIN domain DUF3732 PF12532.3 ETN99131.1 - 0.00061 19.3 7.9 31 4.0 0.0 8.6 4 4 8 12 12 12 0 Protein of unknown function (DUF3732) Proteasome_A_N PF10584.4 ETN99131.1 - 0.00091 18.5 39.5 43 3.5 0.1 15.2 15 0 0 15 15 15 0 Proteasome subunit A N-terminal signature FCP1_C PF09309.5 ETN99131.1 - 0.0035 16.6 0.0 86 2.3 0.0 6.7 5 2 5 11 11 11 0 FCP1, C-terminal UBA PF00627.26 ETN99132.1 - 4.3e-19 67.7 3.4 8.3e-07 28.6 0.1 4.5 4 1 0 4 4 4 3 UBA/TS-N domain UBA_4 PF14555.1 ETN99132.1 - 0.0012 18.3 4.4 0.026 14.0 0.0 4.0 5 0 0 5 5 5 1 UBA-like domain TraH_2 PF06871.6 ETN99132.1 - 0.43 10.0 4.1 2.4 7.5 2.2 2.2 2 0 0 2 2 2 0 TraH_2 Bestrophin PF01062.16 ETN99132.1 - 0.87 8.4 6.1 0.44 9.4 0.4 2.2 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel RNA_pol_3_Rpc31 PF11705.3 ETN99132.1 - 0.98 9.3 19.4 0.093 12.6 8.9 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 TetR_C PF02909.12 ETN99132.1 - 1.9 8.1 7.6 0.26 10.9 0.2 3.1 2 2 1 3 3 3 0 Tetracyclin repressor, C-terminal all-alpha domain RNase_H PF00075.19 ETN99134.1 - 4.1e-09 36.8 0.0 5.9e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 ETN99135.1 - 0.00019 21.6 0.2 0.00025 21.2 0.1 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase HEAT PF02985.17 ETN99136.1 - 2.1e-09 36.6 0.0 0.08 13.0 0.0 4.4 3 1 1 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 ETN99136.1 - 8.7e-08 32.3 0.0 0.00033 20.8 0.0 2.3 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 ETN99136.1 - 1.4e-05 25.4 0.0 0.025 15.0 0.0 2.7 1 1 2 3 3 3 2 HEAT-like repeat Spore_III_AB PF09548.5 ETN99136.1 - 0.00051 19.8 0.2 0.037 13.7 0.0 2.1 1 1 1 2 2 2 1 Stage III sporulation protein AB (spore_III_AB) TIP120 PF08623.5 ETN99136.1 - 0.0013 18.3 2.0 0.63 9.6 0.1 2.7 1 1 2 3 3 3 2 TATA-binding protein interacting (TIP20) Cnd1 PF12717.2 ETN99136.1 - 0.0027 17.5 0.1 0.015 15.1 0.1 2.2 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 DUF3554 PF12074.3 ETN99136.1 - 0.012 15.0 0.1 0.89 8.9 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3554) MOR2-PAG1_N PF14222.1 ETN99136.1 - 0.047 12.3 0.1 2.1 6.9 0.0 2.3 1 1 1 2 2 2 0 Cell morphogenesis N-terminal DUF2791 PF10923.3 ETN99136.1 - 0.093 11.3 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) DUF4197 PF13852.1 ETN99136.1 - 0.095 12.2 0.0 1 8.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4197) DUF3969 PF13108.1 ETN99136.1 - 0.1 12.2 0.3 0.4 10.3 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3969) NLE PF08154.7 ETN99136.1 - 0.12 12.3 0.4 25 4.9 0.0 2.9 3 0 0 3 3 3 0 NLE (NUC135) domain CCDC-167 PF15188.1 ETN99136.1 - 0.13 12.1 2.4 13 5.7 0.0 2.9 2 2 2 4 4 4 0 Coiled-coil domain-containing protein 167 Med8 PF10232.4 ETN99136.1 - 0.15 11.5 0.2 3.9 6.9 0.0 2.1 1 1 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 Calcipressin PF04847.7 ETN99137.1 - 0.043 13.3 0.4 0.043 13.3 0.3 1.7 2 0 0 2 2 2 0 Calcipressin SnAC PF14619.1 ETN99137.1 - 0.057 13.5 1.5 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 Snf2-ATP coupling, chromatin remodelling complex zf-TRAF PF02176.13 ETN99138.1 - 6.1e-06 26.5 2.5 6.1e-06 26.5 1.7 2.4 2 1 0 2 2 2 1 TRAF-type zinc finger PUB PF09409.5 ETN99139.1 - 0.051 13.3 0.6 0.096 12.4 0.4 1.8 1 1 0 1 1 1 0 PUB domain DUF1961 PF09224.6 ETN99140.1 - 0.00024 20.2 31.1 12 4.9 0.2 10.6 1 1 12 14 14 14 10 Domain of unknown function (DUF1961) DUF243 PF03103.12 ETN99140.1 - 0.077 13.1 40.2 19 5.4 0.9 8.7 1 1 6 8 8 8 0 Domain of unknown function (DUF243) Menin PF05053.8 ETN99141.1 - 0.057 11.5 17.1 0.067 11.3 11.8 1.3 1 0 0 1 1 1 0 Menin MIP-T3 PF10243.4 ETN99141.1 - 4.2 5.7 45.6 5 5.4 31.6 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 LMBR1 PF04791.11 ETN99141.1 - 5.1 5.5 7.7 6.8 5.1 5.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Nop14 PF04147.7 ETN99141.1 - 8.3 4.1 33.4 11 3.7 23.2 1.1 1 0 0 1 1 1 0 Nop14-like family RVP PF00077.15 ETN99144.1 - 0.029 14.2 0.1 1.2 9.0 0.0 2.5 2 1 1 3 3 3 0 Retroviral aspartyl protease WD40 PF00400.27 ETN99145.1 - 1.4e-29 100.8 6.1 1.4e-09 37.4 0.3 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat RMMBL PF07521.7 ETN99145.1 - 0.15 11.9 0.9 17 5.3 0.0 2.5 2 0 0 2 2 2 0 RNA-metabolising metallo-beta-lactamase DUF870 PF05912.6 ETN99145.1 - 0.65 9.8 2.8 1.3 8.8 1.9 1.8 1 1 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF870) Kelch_6 PF13964.1 ETN99146.1 - 1.8e-07 31.0 1.0 2.6e-07 30.5 0.5 1.4 1 1 0 1 1 1 1 Kelch motif Kelch_1 PF01344.20 ETN99146.1 - 1.8e-06 27.3 1.3 2.8e-06 26.7 0.9 1.2 1 0 0 1 1 1 1 Kelch motif Kelch_3 PF13415.1 ETN99146.1 - 0.0037 17.3 0.0 0.0049 16.9 0.0 1.3 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETN99146.1 - 0.0046 16.8 1.7 0.0084 16.0 1.2 1.4 1 0 0 1 1 1 1 Kelch motif Kelch_2 PF07646.10 ETN99146.1 - 0.011 15.4 0.2 0.019 14.7 0.1 1.4 1 0 0 1 1 1 0 Kelch motif Kelch_4 PF13418.1 ETN99146.1 - 0.016 14.9 0.2 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Galactose oxidase, central domain zf-C3HC4_2 PF13923.1 ETN99147.1 - 0.079 13.0 4.6 0.89 9.6 3.2 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.15 ETN99147.1 - 1.2 8.7 6.0 0.33 10.4 1.7 1.9 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger RNase_H PF00075.19 ETN99149.1 - 0.015 15.6 0.1 0.028 14.7 0.1 1.5 1 1 0 1 1 1 0 RNase H IL22 PF14565.1 ETN99149.1 - 0.076 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor RVT_3 PF13456.1 ETN99149.1 - 0.1 12.3 0.1 0.38 10.5 0.0 1.9 2 0 0 2 2 2 0 Reverse transcriptase-like PPR_2 PF13041.1 ETN99152.1 - 1.6e-11 43.9 0.3 4.6e-09 36.1 0.1 2.4 2 0 0 2 2 2 2 PPR repeat family PPR_1 PF12854.2 ETN99152.1 - 9.1e-10 37.8 1.0 3.8e-05 23.0 0.0 3.3 3 0 0 3 3 3 3 PPR repeat PPR_3 PF13812.1 ETN99152.1 - 1.7e-05 24.7 0.0 0.0001 22.2 0.0 2.4 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR PF01535.15 ETN99152.1 - 0.00022 20.9 1.7 0.00047 19.9 0.0 2.4 3 0 0 3 3 3 1 PPR repeat ATP13 PF12921.2 ETN99152.1 - 0.034 13.4 0.2 0.034 13.4 0.1 2.1 2 1 1 3 3 3 0 Mitochondrial ATPase expression DUF4277 PF14104.1 ETN99152.1 - 0.069 13.3 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4277) Beta-TrCP_D PF12125.3 ETN99152.1 - 5 6.8 7.2 1.3 8.7 2.3 2.0 2 0 0 2 2 2 0 D domain of beta-TrCP WD40 PF00400.27 ETN99153.1 - 4.2e-35 118.3 2.7 4.2e-11 42.2 0.1 4.0 4 0 0 4 4 4 4 WD domain, G-beta repeat eIF2A PF08662.6 ETN99153.1 - 1.7e-07 31.1 0.0 2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETN99153.1 - 4.7e-05 22.9 3.6 2 8.1 0.0 3.5 3 0 0 3 3 3 3 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETN99153.1 - 0.0021 16.2 0.1 0.0038 15.4 0.0 1.4 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Proteasome_A_N PF10584.4 ETN99153.1 - 0.0035 16.6 2.3 5.9 6.3 0.0 3.4 3 0 0 3 3 3 2 Proteasome subunit A N-terminal signature Mid2 PF04478.7 ETN99153.1 - 0.095 12.1 0.0 0.59 9.5 0.0 1.9 1 1 1 2 2 2 0 Mid2 like cell wall stress sensor MMS1_N PF10433.4 ETN99153.1 - 0.11 10.6 0.0 1.1 7.3 0.0 2.2 1 1 2 3 3 3 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term DPPIV_N PF00930.16 ETN99153.1 - 0.12 10.9 0.0 16 3.9 0.0 2.8 1 1 2 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF1258 PF06869.7 ETN99153.1 - 0.13 11.3 0.2 0.84 8.6 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) NOA36 PF06524.7 ETN99154.1 - 0.88 8.7 7.0 1.6 7.9 4.9 1.5 1 0 0 1 1 1 0 NOA36 protein SNAPc19 PF15497.1 ETN99155.1 - 0.038 14.2 1.1 0.038 14.2 0.7 1.9 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 DUF2072 PF09845.4 ETN99155.1 - 0.23 11.4 2.8 0.13 12.2 0.3 1.7 1 1 1 2 2 2 0 Zn-ribbon containing protein (DUF2072) Rgp1 PF08737.5 ETN99155.1 - 0.24 10.4 4.5 0.28 10.2 3.1 1.0 1 0 0 1 1 1 0 Rgp1 ApoC-I PF04691.7 ETN99157.1 - 0.0018 17.9 0.9 0.0035 16.9 0.2 1.8 2 1 0 2 2 2 1 Apolipoprotein C-I (ApoC-1) Erp_C PF06780.6 ETN99157.1 - 0.029 14.2 4.1 0.048 13.5 2.8 1.6 1 1 0 1 1 1 0 Erp protein C-terminus COXG PF06240.8 ETN99157.1 - 0.045 13.4 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit G (CoxG) Cauli_DNA-bind PF03310.8 ETN99157.1 - 0.62 9.9 3.3 2.3 8.0 2.0 2.0 1 1 1 2 2 2 0 Caulimovirus DNA-binding protein AKNA PF12443.3 ETN99157.1 - 0.78 9.7 6.3 0.37 10.8 1.1 2.3 1 1 0 2 2 2 0 AT-hook-containing transcription factor TPR_12 PF13424.1 ETN99158.1 - 3.6e-104 340.8 10.6 1.4e-25 89.0 0.0 4.3 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETN99158.1 - 5.6e-58 192.4 25.2 9.7e-16 57.1 1.1 4.1 2 1 3 5 5 5 5 TPR repeat TPR_10 PF13374.1 ETN99158.1 - 1.9e-55 183.3 0.0 5.1e-10 38.9 0.0 6.1 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.1 ETN99158.1 - 2.5e-49 161.2 2.1 1.8e-07 30.4 0.0 6.2 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETN99158.1 - 7.7e-47 155.0 31.3 1.7e-09 36.8 0.6 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.12 ETN99158.1 - 5.8e-33 110.1 23.1 3.6e-06 26.4 0.1 6.3 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETN99158.1 - 7.1e-31 103.6 40.0 2e-06 27.1 0.6 6.2 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.1 ETN99158.1 - 3.6e-25 86.0 11.6 0.00025 21.0 0.0 7.4 5 2 0 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 ETN99158.1 - 5.6e-15 55.5 0.0 0.00019 22.0 0.0 4.3 1 1 5 6 6 6 5 Tetratricopeptide repeat MIT PF04212.13 ETN99158.1 - 3.6e-14 52.3 20.8 0.029 14.2 0.1 6.1 4 2 2 6 6 6 4 MIT (microtubule interacting and transport) domain TPR_14 PF13428.1 ETN99158.1 - 1.9e-11 43.5 0.0 2.1 9.2 0.0 6.1 5 1 1 6 6 6 3 Tetratricopeptide repeat PPR PF01535.15 ETN99158.1 - 4.9e-10 38.7 12.3 0.012 15.5 0.1 5.9 6 0 0 6 6 6 2 PPR repeat Apc3 PF12895.2 ETN99158.1 - 7.9e-10 38.7 8.2 0.00087 19.3 0.2 4.1 1 1 4 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETN99158.1 - 1.8e-09 37.4 0.6 2.6 8.6 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETN99158.1 - 2.6e-08 34.0 0.2 0.46 10.8 0.0 4.4 2 1 2 5 5 5 2 Tetratricopeptide repeat DUF2977 PF11192.3 ETN99158.1 - 4.4e-05 23.2 0.2 47 3.9 0.0 5.7 6 0 0 6 6 6 0 Protein of unknown function (DUF2977) Pep3_Vps18 PF05131.9 ETN99158.1 - 7.7e-05 22.1 0.7 30 4.0 0.0 5.3 6 0 0 6 6 6 0 Pep3/Vps18/deep orange family Musclin PF11037.3 ETN99158.1 - 0.00032 20.3 0.0 8.8 5.9 0.0 4.4 4 2 1 5 5 5 0 Insulin-resistance promoting peptide in skeletal muscle TPR_3 PF07720.7 ETN99158.1 - 0.0004 20.0 25.5 1.2 9.0 0.1 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETN99158.1 - 0.00052 19.8 11.4 5.8 6.8 0.1 5.9 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat KH_4 PF13083.1 ETN99158.1 - 0.00054 19.5 0.0 0.61 9.7 0.0 2.9 2 1 1 3 3 2 2 KH domain PPR_2 PF13041.1 ETN99158.1 - 0.0019 18.1 0.9 13 5.8 0.0 4.2 4 0 0 4 4 4 0 PPR repeat family DUF627 PF04781.7 ETN99158.1 - 0.0023 17.5 6.9 5.1 6.7 0.0 5.0 2 2 3 5 5 5 1 Protein of unknown function (DUF627) MCM_N PF14551.1 ETN99158.1 - 0.075 13.5 0.3 9.3 6.7 0.2 3.6 1 1 0 1 1 1 0 MCM N-terminal domain TPR_5 PF12688.2 ETN99158.1 - 0.094 12.7 0.2 19 5.2 0.0 3.5 3 1 1 4 4 4 0 Tetratrico peptide repeat NdhO PF11910.3 ETN99158.1 - 0.15 11.7 1.6 6.7 6.4 0.1 3.3 2 1 2 4 4 3 0 Cyanobacterial and plant NDH-1 subunit O DUF1936 PF09151.5 ETN99158.1 - 7.7 6.1 9.2 45 3.6 0.1 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF1936) NUDIX PF00293.23 ETN99160.1 - 6.9e-05 22.4 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain zf-Di19 PF05605.7 ETN99160.1 - 0.00043 20.3 5.6 0.056 13.5 0.2 2.5 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 ETN99160.1 - 0.00072 19.7 3.3 0.15 12.4 0.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger NUDIX_2 PF13869.1 ETN99160.1 - 0.0045 16.3 0.2 0.01 15.1 0.1 1.6 1 0 0 1 1 1 1 Nucleotide hydrolase zf-C2H2_6 PF13912.1 ETN99160.1 - 0.016 15.0 5.0 0.06 13.2 0.5 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 ETN99160.1 - 0.019 15.3 1.8 0.019 15.3 1.2 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type Rad50_zn_hook PF04423.9 ETN99160.1 - 0.032 13.6 0.1 0.096 12.1 0.1 1.8 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-C2H2_2 PF12756.2 ETN99160.1 - 0.085 12.9 7.7 4.5 7.4 5.3 2.7 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF2985 PF11204.3 ETN99161.1 - 0.23 11.2 4.9 0.4 10.4 3.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2985) Mu-like_Com PF10122.4 ETN99164.1 - 0.084 11.9 0.3 0.11 11.5 0.2 1.3 1 0 0 1 1 1 0 Mu-like prophage protein Com LRS4 PF10422.4 ETN99164.1 - 0.44 9.8 2.5 0.63 9.3 1.7 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 WD40 PF00400.27 ETN99165.1 - 1.3e-45 151.7 14.8 4.2e-11 42.2 0.1 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETN99165.1 - 6.2e-11 41.1 0.2 0.00022 19.5 0.0 3.9 1 1 2 4 4 4 4 Nucleoporin Nup120/160 DUF851 PF05867.6 ETN99165.1 - 6.9e-06 25.4 0.0 0.0088 15.3 0.0 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF851) Rax2 PF12768.2 ETN99165.1 - 6.6e-05 22.2 1.9 9.7e-05 21.7 1.3 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity DUF1900 PF08954.6 ETN99165.1 - 0.00074 19.0 0.1 0.4 10.1 0.0 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF1900) Nucleoporin_N PF08801.6 ETN99165.1 - 0.00086 18.1 5.7 0.38 9.4 2.6 3.4 1 1 1 2 2 2 1 Nup133 N terminal like BBS2_Mid PF14783.1 ETN99165.1 - 0.0015 18.2 0.5 5 6.9 0.0 3.7 2 1 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.1 ETN99165.1 - 0.065 12.6 0.1 0.84 9.0 0.0 2.2 2 1 0 2 2 2 0 PQQ-like domain Peptidase_C50 PF03568.12 ETN99166.1 - 0.019 13.6 2.5 0.02 13.5 1.7 1.1 1 0 0 1 1 1 0 Peptidase family C50 GPI PF06560.6 ETN99166.1 - 0.07 12.1 0.1 0.11 11.4 0.1 1.5 1 1 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) ABC_transp_aux PF09822.4 ETN99167.1 - 0.0035 16.8 0.0 0.0047 16.4 0.0 1.1 1 0 0 1 1 1 1 ABC-type uncharacterized transport system DUF4350 PF14258.1 ETN99167.1 - 0.13 12.4 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) HSBP1 PF06825.7 ETN99168.1 - 0.0045 16.5 2.1 0.12 11.9 0.0 3.4 3 1 0 3 3 3 1 Heat shock factor binding protein 1 HHH_5 PF14520.1 ETN99168.1 - 0.12 12.5 0.1 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain Sas10_Utp3 PF04000.10 ETN99169.1 - 0.12 12.5 0.3 0.2 11.8 0.2 1.5 1 0 0 1 1 1 0 Sas10/Utp3/C1D family Ank_5 PF13857.1 ETN99170.1 - 0.15 12.3 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DUF4219 PF13961.1 ETN99172.1 - 0.35 10.3 2.7 1 8.8 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) Chordopox_A13L PF05961.6 ETN99173.1 - 0.0067 16.3 1.9 0.021 14.7 1.3 1.8 1 0 0 1 1 1 1 Chordopoxvirus A13L protein DUF1686 PF07937.6 ETN99173.1 - 0.07 12.7 0.1 0.097 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1686) AHSP PF09236.5 ETN99173.1 - 0.37 11.0 3.9 0.53 10.5 0.3 2.7 2 1 1 3 3 3 0 Alpha-haemoglobin stabilising protein UPF0184 PF03670.8 ETN99173.1 - 0.53 10.4 6.0 0.42 10.8 0.4 2.5 2 1 0 3 3 3 0 Uncharacterised protein family (UPF0184) CTP-dep_RFKase PF01982.11 ETN99174.1 - 0.036 13.7 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF120 RPAP3_C PF13877.1 ETN99175.1 - 0.24 11.3 3.5 7.7 6.5 0.2 2.2 1 1 1 2 2 2 0 Potential Monad-binding region of RPAP3 Copine PF07002.11 ETN99176.1 - 9.8e-10 38.3 0.0 1.8e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Copine Med3 PF11593.3 ETN99177.1 - 0.22 10.7 13.4 0.24 10.6 9.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MGC-24 PF05283.6 ETN99177.1 - 0.68 9.7 13.8 0.81 9.4 9.5 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Herpes_capsid PF06112.6 ETN99177.1 - 2.7 8.0 10.1 4.3 7.3 7.0 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF1639 PF07797.9 ETN99178.1 - 0.08 12.3 0.1 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1639) ubiquitin PF00240.18 ETN99182.1 - 2.5e-07 29.9 0.3 5.5e-07 28.8 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 ETN99182.1 - 0.017 14.8 0.2 0.5 10.0 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like SAPS PF04499.10 ETN99182.1 - 1.6 7.3 9.2 1.7 7.2 6.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Strabismus PF06638.6 ETN99182.1 - 4.5 5.4 6.3 5.5 5.1 4.4 1.1 1 0 0 1 1 1 0 Strabismus protein Telomere_Sde2 PF13019.1 ETN99182.1 - 7.2 6.2 10.3 1.8 8.2 3.8 2.1 2 1 0 2 2 2 0 Telomere stability and silencing Neur_chan_memb PF02932.11 ETN99182.1 - 7.8 6.3 11.6 5.3 6.8 7.2 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region UN_NPL4 PF11543.3 ETN99184.1 - 0.014 15.6 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 PB1 PF00564.19 ETN99184.1 - 0.099 12.3 0.2 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 PB1 domain EF-hand_5 PF13202.1 ETN99184.1 - 1.7 8.1 0.1 1.7 8.1 0.0 2.3 2 0 0 2 2 2 0 EF hand DUF2051 PF09738.4 ETN99185.1 - 0.1 11.9 2.3 0.23 10.7 1.5 1.6 1 1 1 2 2 2 0 Double stranded RNA binding protein (DUF2051) WD40 PF00400.27 ETN99186.1 - 1.2e-05 24.9 0.1 0.00094 18.9 0.1 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat zf-LITAF-like PF10601.4 ETN99189.1 - 2.9 7.8 6.2 2 8.3 1.0 2.3 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Choline_sulf_C PF12411.3 ETN99190.1 - 0.03 14.1 0.4 0.057 13.2 0.2 1.5 1 0 0 1 1 1 0 Choline sulfatase enzyme C terminal Laminin_II PF06009.7 ETN99191.1 - 2.3e-05 24.1 2.3 3.5e-05 23.5 1.6 1.2 1 0 0 1 1 1 1 Laminin Domain II Reo_sigmaC PF04582.7 ETN99191.1 - 8e-05 21.9 3.4 0.0001 21.6 2.3 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein COG2 PF06148.6 ETN99191.1 - 0.00038 20.3 0.5 0.00066 19.5 0.4 1.5 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps5 PF09325.5 ETN99191.1 - 0.00046 19.5 3.9 0.00062 19.0 2.7 1.1 1 0 0 1 1 1 1 Vps5 C terminal like IFT57 PF10498.4 ETN99191.1 - 0.0021 16.9 3.1 0.0027 16.5 2.1 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Fib_alpha PF08702.5 ETN99191.1 - 0.0046 17.1 6.2 0.0069 16.5 4.3 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family XhlA PF10779.4 ETN99191.1 - 0.0077 16.1 4.1 0.019 14.8 2.8 1.7 1 0 0 1 1 1 1 Haemolysin XhlA Serine_rich PF08824.5 ETN99191.1 - 0.011 15.4 1.6 0.015 15.0 1.1 1.1 1 0 0 1 1 1 0 Serine rich protein interaction domain KaiC PF06745.8 ETN99191.1 - 0.011 14.8 0.3 0.017 14.2 0.2 1.3 1 0 0 1 1 1 0 KaiC MCPsignal PF00015.16 ETN99191.1 - 0.021 14.3 1.9 0.031 13.8 1.3 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF4208 PF13907.1 ETN99191.1 - 0.025 14.7 1.2 0.08 13.1 1.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) Allexi_40kDa PF05549.6 ETN99191.1 - 0.031 13.5 1.2 0.038 13.3 0.8 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein LPP PF04728.8 ETN99191.1 - 0.034 13.9 5.2 0.19 11.5 2.8 2.2 1 1 1 2 2 2 0 Lipoprotein leucine-zipper DUF948 PF06103.6 ETN99191.1 - 0.039 13.8 3.3 0.16 11.8 2.0 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) LOH1CR12 PF10158.4 ETN99191.1 - 0.043 13.5 2.6 0.065 13.0 1.8 1.3 1 0 0 1 1 1 0 Tumour suppressor protein Tup_N PF08581.5 ETN99191.1 - 0.059 13.5 2.8 0.08 13.1 0.3 2.1 1 1 1 2 2 2 0 Tup N-terminal Prefoldin_3 PF13758.1 ETN99191.1 - 0.067 12.9 1.4 0.094 12.4 1.0 1.2 1 0 0 1 1 1 0 Prefoldin subunit Syntaxin PF00804.20 ETN99191.1 - 0.072 13.2 6.5 0.11 12.6 4.5 1.3 1 0 0 1 1 1 0 Syntaxin PG_binding_4 PF12229.3 ETN99191.1 - 0.074 13.2 0.3 0.074 13.2 0.2 1.9 1 1 1 2 2 2 0 Putative peptidoglycan binding domain Vps51 PF08700.6 ETN99191.1 - 0.076 12.8 10.5 2.4 8.0 0.3 3.2 2 1 1 3 3 3 0 Vps51/Vps67 DELLA PF12041.3 ETN99191.1 - 0.079 12.6 1.8 0.17 11.5 0.5 1.9 1 1 1 2 2 2 0 Transcriptional regulator DELLA protein N terminal RmuC PF02646.11 ETN99191.1 - 0.083 11.7 4.9 0.11 11.3 1.2 1.9 1 1 1 2 2 2 0 RmuC family DUF2664 PF10867.3 ETN99191.1 - 0.11 13.1 1.1 0.15 12.7 0.2 1.6 1 1 1 2 2 1 0 Protein of unknown function (DUF2664) TBPIP PF07106.8 ETN99191.1 - 0.11 12.0 9.6 0.27 10.7 6.7 1.6 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) V_ATPase_I PF01496.14 ETN99191.1 - 0.13 10.1 2.4 0.15 9.8 1.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.7 ETN99191.1 - 0.16 11.7 4.2 0.52 10.1 3.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) CytochromB561_N PF09786.4 ETN99191.1 - 0.19 10.1 4.9 0.23 9.8 3.4 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Syntaxin-6_N PF09177.6 ETN99191.1 - 0.21 12.0 1.9 1 9.7 1.3 2.0 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Syntaxin_2 PF14523.1 ETN99191.1 - 0.25 11.4 7.7 6.1 6.9 5.3 2.3 1 1 0 1 1 1 0 Syntaxin-like protein Med4 PF10018.4 ETN99191.1 - 0.28 10.5 3.9 2 7.8 2.7 1.9 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 ALMT PF11744.3 ETN99191.1 - 0.31 9.6 2.9 0.35 9.4 2.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Spc24 PF08286.6 ETN99191.1 - 0.75 9.4 9.5 1.6 8.4 1.3 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DASH_Dam1 PF08653.5 ETN99191.1 - 1.2 8.9 7.8 8.8 6.1 0.2 2.9 1 1 1 2 2 2 0 DASH complex subunit Dam1 DUF972 PF06156.8 ETN99191.1 - 2.1 8.7 5.9 5.3 7.4 4.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DASH_Dad3 PF08656.5 ETN99191.1 - 2.7 7.7 5.9 44 3.8 4.1 2.7 1 1 0 1 1 1 0 DASH complex subunit Dad3 FlaC_arch PF05377.6 ETN99191.1 - 4 7.3 8.3 1.2e+02 2.7 4.5 3.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DASH_Dad1 PF08649.5 ETN99191.1 - 5.9 6.6 10.0 1.2 8.8 0.7 2.6 1 1 1 2 2 2 0 DASH complex subunit Dad1 Mic1 PF07035.7 ETN99192.1 - 0.032 13.5 0.2 0.13 11.6 0.0 1.9 2 0 0 2 2 2 0 Colon cancer-associated protein Mic1-like tRNA_bind PF01588.15 ETN99193.1 - 1.5e-25 88.8 0.0 2.3e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Putative tRNA binding domain RelA_SpoT PF04607.12 ETN99194.1 - 0.0085 16.0 2.0 0.0088 16.0 0.1 1.9 2 1 0 2 2 2 1 Region found in RelA / SpoT proteins Peptidase_C14 PF00656.17 ETN99195.1 - 1.1e-11 44.9 0.0 1.3e-11 44.6 0.0 1.0 1 0 0 1 1 1 1 Caspase domain DUF1738 PF08401.6 ETN99196.1 - 0.12 12.0 0.4 0.25 11.0 0.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1738) SecE PF00584.15 ETN99197.1 - 0.015 14.8 0.1 0.022 14.2 0.1 1.3 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex WD40 PF00400.27 ETN99199.1 - 1.3e-11 43.8 0.2 2.2e-10 39.9 0.1 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF1336 PF07059.7 ETN99199.1 - 0.053 12.9 0.8 0.063 12.6 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1336) Caps_synth PF05704.7 ETN99199.1 - 0.07 12.2 8.7 0.11 11.6 5.9 1.4 1 1 0 1 1 1 0 Capsular polysaccharide synthesis protein RNA_pol_Rpb4 PF03874.11 ETN99199.1 - 0.079 12.9 0.5 0.11 12.4 0.3 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb4 Cullin_binding PF03556.10 ETN99199.1 - 0.25 11.4 3.0 0.44 10.6 2.1 1.3 1 0 0 1 1 1 0 Cullin binding CblD PF07434.6 ETN99200.1 - 0.096 11.3 0.0 0.096 11.3 0.0 1.2 1 0 0 1 1 1 0 CblD like pilus biogenesis initiator Zip PF02535.17 ETN99201.1 - 3.3 6.6 12.3 4.3 6.2 8.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter FA_desaturase PF00487.19 ETN99201.1 - 5.3 6.4 8.0 7.5 5.9 5.6 1.2 1 0 0 1 1 1 0 Fatty acid desaturase WD40 PF00400.27 ETN99202.1 - 4.2e-11 42.2 0.0 6.4e-09 35.3 0.0 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat HAD PF12710.2 ETN99202.1 - 0.051 13.7 0.0 0.051 13.7 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase zf-C3HC4_2 PF13923.1 ETN99204.1 - 0.017 15.1 2.2 0.15 12.1 1.5 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ING PF12998.2 ETN99205.1 - 0.12 12.6 0.2 0.12 12.6 0.1 2.8 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding DUF1423 PF07227.6 ETN99205.1 - 2 7.0 8.8 1.4 7.4 4.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1423) WD40 PF00400.27 ETN99207.1 - 1.1e-32 110.7 11.4 6.3e-10 38.5 0.1 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETN99207.1 - 2.9e-07 29.0 1.4 0.013 13.7 0.1 3.7 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Peptidase_S55 PF05580.7 ETN99207.1 - 0.022 14.2 0.1 0.071 12.5 0.0 1.7 1 1 1 2 2 2 0 SpoIVB peptidase S55 BBS2_Mid PF14783.1 ETN99207.1 - 0.079 12.7 0.7 38 4.0 0.0 3.7 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.27 ETN99209.1 - 6.9e-23 79.6 9.5 1.6e-09 37.3 0.0 3.8 2 1 2 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN99209.1 - 0.00021 19.5 0.3 0.014 13.5 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETN99209.1 - 0.0042 15.9 3.5 0.19 10.4 2.4 2.2 1 1 0 1 1 1 1 Nup133 N terminal like DUF1541 PF07563.6 ETN99209.1 - 0.037 13.7 0.0 0.58 9.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1541) PQQ_2 PF13360.1 ETN99209.1 - 0.055 12.9 0.2 0.79 9.1 0.1 1.9 1 1 1 2 2 2 0 PQQ-like domain Kelch_6 PF13964.1 ETN99209.1 - 0.51 10.5 2.6 89 3.5 0.1 3.6 3 0 0 3 3 3 0 Kelch motif UBN_AB PF14075.1 ETN99210.1 - 0.019 14.6 2.7 0.023 14.3 1.8 1.1 1 0 0 1 1 1 0 Ubinuclein conserved middle domain DnaB_C PF03796.10 ETN99210.1 - 0.055 12.3 2.1 0.063 12.1 1.5 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Sec2p PF06428.6 ETN99210.1 - 0.2 11.5 4.4 0.51 10.2 3.0 1.7 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p Bacillus_HBL PF05791.6 ETN99210.1 - 0.63 9.3 6.9 30 3.9 4.7 2.0 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Pox_A_type_inc PF04508.7 ETN99210.1 - 7.8 6.5 6.3 8.7 6.4 0.1 3.1 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DUF790 PF05626.6 ETN99211.1 - 0.037 12.5 0.4 0.039 12.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF790) DUF1387 PF07139.6 ETN99215.1 - 2.8 7.4 11.5 3.4 7.2 8.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DUF3523 PF12037.3 ETN99215.1 - 3.6 6.4 22.8 4.6 6.1 15.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) DUF2315 PF10231.4 ETN99216.1 - 1 9.2 8.6 3.2 7.6 0.2 2.2 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2315) DUF3416 PF11896.3 ETN99217.1 - 0.003 17.5 0.1 0.033 14.1 0.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF3416) SPT16 PF08644.6 ETN99218.1 - 0.12 12.2 5.4 0.2 11.5 3.8 1.4 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) DUF3818 PF12825.2 ETN99219.1 - 4.3 5.9 7.4 5.3 5.6 5.1 1.0 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) DUF4407 PF14362.1 ETN99219.1 - 7.7 5.3 7.6 10 5.0 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UCR_hinge PF02320.11 ETN99220.1 - 0.0049 16.7 5.0 0.058 13.3 3.5 2.3 1 1 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein UPF0203 PF05254.7 ETN99220.1 - 0.014 15.2 7.4 0.88 9.4 0.4 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) HMG_box PF00505.14 ETN99220.1 - 0.037 14.2 0.1 0.099 12.9 0.1 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box BTB_2 PF02214.17 ETN99220.1 - 0.052 13.7 2.8 0.68 10.1 0.1 2.6 2 1 0 2 2 2 0 BTB/POZ domain HMG_box_2 PF09011.5 ETN99220.1 - 0.054 13.8 0.1 0.17 12.2 0.1 1.8 1 0 0 1 1 1 0 HMG-box domain COX6B PF02297.12 ETN99220.1 - 0.78 9.7 6.4 0.16 11.9 1.3 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb TPR_12 PF13424.1 ETN99221.1 - 8.1e-06 25.6 0.0 1.2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETN99221.1 - 6.5e-05 22.3 0.2 0.0001 21.7 0.1 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETN99221.1 - 0.00027 20.5 0.3 0.00061 19.3 0.2 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETN99221.1 - 0.0012 18.7 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETN99221.1 - 0.0014 18.1 0.1 0.0022 17.6 0.1 1.2 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 ETN99221.1 - 0.026 14.4 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETN99221.1 - 0.028 14.2 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Nup160 PF11715.3 ETN99223.1 - 0.0011 17.1 0.1 0.002 16.3 0.1 1.5 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Bac_DnaA PF00308.13 ETN99223.1 - 0.06 12.9 1.1 0.089 12.4 0.8 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein TPR_11 PF13414.1 ETN99224.1 - 0.0016 18.0 0.3 0.0067 16.0 0.0 2.0 2 0 0 2 2 2 1 TPR repeat BCDHK_Adom3 PF10436.4 ETN99224.1 - 0.0076 15.7 1.7 0.037 13.5 0.8 1.9 1 1 1 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DUF4301 PF14134.1 ETN99224.1 - 0.02 13.4 2.4 0.023 13.2 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4301) Casc1 PF12366.3 ETN99224.1 - 0.057 12.9 6.7 0.071 12.5 4.6 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 TPR_16 PF13432.1 ETN99224.1 - 0.085 13.5 0.0 0.17 12.5 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4175 PF13779.1 ETN99224.1 - 0.13 9.9 10.3 0.16 9.6 7.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Hist_deacetyl PF00850.14 ETN99224.1 - 0.16 11.2 0.9 0.18 11.0 0.6 1.1 1 0 0 1 1 1 0 Histone deacetylase domain TPR_2 PF07719.12 ETN99224.1 - 0.16 11.9 1.1 3.4 7.8 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4484 PF14831.1 ETN99224.1 - 0.31 11.1 4.6 0.39 10.8 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) zf-C4H2 PF10146.4 ETN99224.1 - 0.4 10.6 9.9 0.5 10.3 6.9 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein TPR_1 PF00515.23 ETN99224.1 - 0.42 10.3 2.3 1.7 8.3 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Orbi_VP5 PF00901.12 ETN99224.1 - 0.97 7.5 5.4 1 7.4 3.7 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 DNA_pol_B PF00136.16 ETN99224.1 - 2.1 7.0 6.4 2.4 6.8 4.4 1.0 1 0 0 1 1 1 0 DNA polymerase family B NinG PF05766.7 ETN99224.1 - 3.1 7.5 7.4 3.4 7.3 4.7 1.3 1 1 0 1 1 1 0 Bacteriophage Lambda NinG protein GBP_C PF02841.9 ETN99224.1 - 3.1 6.8 13.8 3.5 6.7 9.6 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain HSP70 PF00012.15 ETN99224.1 - 7 4.4 10.0 7.4 4.3 6.9 1.0 1 0 0 1 1 1 0 Hsp70 protein WD40 PF00400.27 ETN99226.1 - 6.2e-11 41.7 7.4 3.2e-08 33.1 1.3 2.6 2 1 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETN99226.1 - 1.1e-05 23.8 0.8 1.5e-05 23.3 0.6 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Col_cuticle_N PF01484.12 ETN99226.1 - 0.22 11.2 1.3 0.64 9.7 0.1 2.3 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain Mnd1 PF03962.10 ETN99226.1 - 0.56 9.8 18.2 0.42 10.2 10.6 2.0 1 1 1 2 2 2 0 Mnd1 family DUF972 PF06156.8 ETN99226.1 - 0.88 9.9 14.3 1.2 9.4 5.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Sec20 PF03908.8 ETN99226.1 - 1.5 8.5 10.6 0.39 10.4 4.1 2.2 1 1 2 3 3 3 0 Sec20 ADIP PF11559.3 ETN99226.1 - 4.6 7.1 20.8 0.99 9.2 7.6 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2681 PF10883.3 ETN99226.1 - 7.3 6.8 19.7 0.045 13.9 2.5 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) DUF3450 PF11932.3 ETN99228.1 - 6.2e-05 22.3 3.0 8.2e-05 21.9 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) ADIP PF11559.3 ETN99228.1 - 8.2e-05 22.5 3.2 0.00012 22.0 1.9 1.6 1 1 0 1 1 1 1 Afadin- and alpha -actinin-Binding Syntaxin PF00804.20 ETN99228.1 - 0.00091 19.3 0.9 0.023 14.8 0.1 2.2 1 1 1 2 2 2 1 Syntaxin DUF1664 PF07889.7 ETN99228.1 - 0.011 15.5 0.6 0.016 14.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) RRF_GI PF12614.3 ETN99228.1 - 0.015 15.1 0.4 0.032 14.0 0.2 1.6 1 1 0 1 1 1 0 Ribosome recycling factor DUF641 PF04859.7 ETN99228.1 - 0.02 14.6 0.8 0.034 13.8 0.4 1.5 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) NPV_P10 PF05531.7 ETN99228.1 - 0.022 15.0 0.3 0.057 13.6 0.2 1.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.7 ETN99228.1 - 0.029 14.1 1.1 0.044 13.5 0.7 1.2 1 0 0 1 1 1 0 Laminin Domain II Atg14 PF10186.4 ETN99228.1 - 0.029 13.3 1.1 0.035 13.0 0.8 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 YlqD PF11068.3 ETN99228.1 - 0.044 13.8 4.7 0.073 13.1 3.2 1.4 1 0 0 1 1 1 0 YlqD protein MbeD_MobD PF04899.7 ETN99228.1 - 0.045 13.6 2.9 0.15 11.9 1.2 2.3 1 1 1 2 2 2 0 MbeD/MobD like FlaC_arch PF05377.6 ETN99228.1 - 0.049 13.5 0.2 7.7 6.4 0.0 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Phage_GPO PF05929.6 ETN99228.1 - 0.065 12.4 1.2 0.075 12.2 0.8 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Tropomyosin_1 PF12718.2 ETN99228.1 - 0.076 12.8 1.7 0.16 11.8 1.0 1.5 1 1 1 2 2 2 0 Tropomyosin like G6PD_N PF00479.17 ETN99228.1 - 0.086 13.0 2.4 0.1 12.8 1.6 1.1 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain V-SNARE_C PF12352.3 ETN99228.1 - 0.091 12.8 0.5 5.8 7.0 0.3 2.4 1 1 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus IncA PF04156.9 ETN99228.1 - 0.11 12.0 1.4 0.13 11.8 0.9 1.3 1 0 0 1 1 1 0 IncA protein Mod_r PF07200.8 ETN99228.1 - 0.14 12.0 3.9 0.1 12.5 1.0 1.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein HALZ PF02183.13 ETN99228.1 - 0.16 11.7 2.7 0.35 10.6 0.6 2.4 2 1 1 3 3 2 0 Homeobox associated leucine zipper DUF4618 PF15397.1 ETN99228.1 - 0.17 11.1 6.0 0.086 12.1 2.3 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) BLOC1_2 PF10046.4 ETN99228.1 - 0.21 11.7 2.7 2.2 8.4 1.1 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.10 ETN99228.1 - 0.23 10.9 5.4 0.12 11.8 1.2 2.4 2 1 0 3 3 3 0 Septum formation initiator Med4 PF10018.4 ETN99228.1 - 0.24 10.7 2.3 0.99 8.7 0.4 2.0 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Acetyltransf_11 PF13720.1 ETN99228.1 - 0.25 11.5 1.7 5.4 7.3 0.1 2.6 2 1 1 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 TMF_DNA_bd PF12329.3 ETN99228.1 - 0.51 10.1 4.1 0.26 11.0 0.4 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.5 ETN99228.1 - 0.85 9.7 4.6 0.28 11.2 0.9 1.9 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family NACHT PF05729.7 ETN99229.1 - 5.1e-08 32.7 0.0 8.1e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain CsgG PF03783.9 ETN99229.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Curli production assembly/transport component CsgG GST_N_2 PF13409.1 ETN99230.1 - 0.05 13.5 0.1 0.088 12.8 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain NOA36 PF06524.7 ETN99231.1 - 9.1 5.4 27.2 19 4.3 18.9 1.5 1 0 0 1 1 1 0 NOA36 protein DUF1031 PF06275.6 ETN99232.1 - 0.064 13.2 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) Microtub_assoc PF07989.6 ETN99233.1 - 0.0077 16.0 4.8 0.0077 16.0 3.3 1.5 1 1 0 1 1 1 1 Microtubule associated DUF4611 PF15387.1 ETN99233.1 - 0.0078 16.3 1.3 0.009 16.1 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) Clathrin_lg_ch PF01086.12 ETN99233.1 - 0.02 14.8 10.2 0.024 14.5 7.1 1.1 1 0 0 1 1 1 0 Clathrin light chain DUF1451 PF07295.6 ETN99233.1 - 0.1 12.3 3.1 0.11 12.2 2.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) DUF912 PF06024.7 ETN99233.1 - 0.11 12.5 0.4 0.13 12.3 0.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4337 PF14235.1 ETN99233.1 - 0.26 11.1 1.2 0.28 10.9 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) RNA_pol_Rbc25 PF08292.7 ETN99233.1 - 0.67 10.1 4.4 0.78 9.9 3.1 1.1 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 PPR PF01535.15 ETN99234.1 - 9.2e-06 25.3 0.8 0.088 12.8 0.0 3.3 3 0 0 3 3 3 2 PPR repeat PPR_2 PF13041.1 ETN99234.1 - 0.00017 21.4 2.2 0.015 15.2 0.3 3.0 2 1 1 3 3 3 2 PPR repeat family DUF1900 PF08954.6 ETN99234.1 - 0.00086 18.8 0.3 0.0053 16.2 0.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1900) PPR_3 PF13812.1 ETN99234.1 - 0.018 15.2 0.0 6.9 7.2 0.0 3.1 3 0 0 3 3 3 0 Pentatricopeptide repeat domain zf-TRAF PF02176.13 ETN99235.1 - 2.1e-07 31.2 2.5 2.1e-07 31.2 1.7 2.3 2 0 0 2 2 2 1 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 ETN99235.1 - 2 8.5 7.7 0.38 10.8 0.3 3.2 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Peroxin-13_N PF04088.8 ETN99236.1 - 0.038 13.9 0.9 0.24 11.3 0.1 2.4 2 0 0 2 2 2 0 Peroxin 13, N-terminal region DUF912 PF06024.7 ETN99236.1 - 0.094 12.7 5.1 4.2 7.4 0.8 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ETRAMP PF09716.5 ETN99236.1 - 0.2 11.6 5.8 1.8 8.5 0.1 2.6 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Phage_int_SAM_1 PF02899.12 ETN99237.1 - 0.039 14.1 1.2 0.28 11.3 0.0 2.8 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain MutS_III PF05192.13 ETN99237.1 - 2.3 7.9 18.7 0.49 10.1 0.1 3.2 1 1 0 2 2 2 0 MutS domain III Fzo_mitofusin PF04799.8 ETN99237.1 - 6.3 6.1 21.7 1.6 8.0 2.1 3.6 1 1 2 3 3 3 0 fzo-like conserved region Protocadherin PF08374.6 ETN99238.1 - 0.00098 18.8 1.6 0.0012 18.5 1.1 1.1 1 0 0 1 1 1 1 Protocadherin AgrB PF04647.10 ETN99238.1 - 0.3 10.1 4.3 0.43 9.6 2.5 1.6 1 1 1 2 2 2 0 Accessory gene regulator B BAR PF03114.13 ETN99238.1 - 0.4 10.1 4.4 0.49 9.8 3.1 1.1 1 0 0 1 1 1 0 BAR domain DUF2116 PF09889.4 ETN99238.1 - 1.2 9.0 5.3 0.68 9.7 1.4 2.2 1 1 2 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Mannosyl_trans2 PF04188.8 ETN99239.1 - 0.068 12.0 0.2 0.075 11.9 0.1 1.0 1 0 0 1 1 1 0 Mannosyltransferase (PIG-V)) Mst1_SARAH PF11629.3 ETN99240.1 - 0.013 15.2 0.3 0.029 14.1 0.2 1.6 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 PH_8 PF15409.1 ETN99241.1 - 0.024 14.7 0.1 0.039 14.0 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain VWA_2 PF13519.1 ETN99241.1 - 0.037 14.1 0.0 0.049 13.7 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain Toxin_trans PF07952.7 ETN99242.1 - 0.067 12.0 0.2 0.075 11.9 0.1 1.2 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain HTH_Mga PF08280.6 ETN99242.1 - 0.09 12.5 0.4 2.2 8.1 0.0 2.2 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain PTS_EIIB PF00367.15 ETN99242.1 - 0.13 11.5 0.2 0.23 10.7 0.1 1.3 1 0 0 1 1 1 0 phosphotransferase system, EIIB Cir_N PF10197.4 ETN99243.1 - 4.4 7.4 13.4 6.4 6.8 9.3 1.4 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR Spc42p PF11544.3 ETN99244.1 - 0.11 12.4 1.2 0.23 11.4 0.8 1.5 1 0 0 1 1 1 0 Spindle pole body component Spc42p FUR PF01475.14 ETN99245.1 - 0.0016 18.3 0.3 0.0023 17.8 0.2 1.3 1 0 0 1 1 1 1 Ferric uptake regulator family HTH_Tnp_Tc3_2 PF01498.13 ETN99245.1 - 0.0063 16.5 0.3 0.014 15.4 0.1 1.7 1 1 1 2 2 2 1 Transposase Lipoprotein_11 PF03260.8 ETN99245.1 - 0.0091 15.0 1.0 0.011 14.7 0.7 1.1 1 0 0 1 1 1 1 Lepidopteran low molecular weight (30 kD) lipoprotein DIT1_PvcA PF05141.7 ETN99245.1 - 0.0098 15.2 0.8 0.012 14.9 0.5 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein DOCK-C2 PF14429.1 ETN99248.1 - 5.4e-21 75.0 1.1 1.7e-20 73.4 0.1 2.3 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 ETN99249.1 - 8.1e-26 90.3 0.5 8.1e-26 90.3 0.4 2.8 3 0 0 3 3 3 1 Dedicator of cytokinesis CDC27 PF09507.5 ETN99251.1 - 0.00075 18.8 31.4 0.0009 18.5 21.8 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Osteopontin PF00865.13 ETN99251.1 - 0.21 10.7 31.5 0.39 9.9 21.8 1.5 1 0 0 1 1 1 0 Osteopontin CobT PF06213.7 ETN99251.1 - 3.4 6.7 29.2 7.7 5.5 20.2 1.7 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TRAP_alpha PF03896.11 ETN99251.1 - 7.7 5.4 18.4 16 4.4 12.7 1.6 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF384 PF04064.8 ETN99252.1 - 0.0081 15.7 0.3 0.0091 15.5 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF384) DUF1664 PF07889.7 ETN99252.1 - 0.25 11.1 1.8 5.3 6.8 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) MBOAT PF03062.14 ETN99254.1 - 0.00024 20.3 9.7 0.00024 20.3 6.7 2.1 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family DUF1925 PF09094.6 ETN99254.1 - 0.17 11.8 0.9 0.38 10.7 0.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1925) G-gamma PF00631.17 ETN99255.1 - 0.0014 18.3 0.1 0.0046 16.6 0.1 1.9 1 0 0 1 1 1 1 GGL domain ALS_ss_C PF10369.4 ETN99255.1 - 0.096 12.4 0.9 3.6 7.3 0.0 2.7 2 0 0 2 2 2 0 Small subunit of acetolactate synthase ETC_C1_NDUFA5 PF04716.9 ETN99255.1 - 0.28 10.7 0.1 0.28 10.7 0.1 3.0 3 1 0 3 3 3 0 ETC complex I subunit conserved region PIN_2 PF10130.4 ETN99255.1 - 1.6 8.7 6.6 0.56 10.2 2.2 2.0 2 0 0 2 2 2 0 PIN domain RNA_pol_Rpb5_C PF01191.14 ETN99255.1 - 2.6 7.7 8.4 3.9 7.1 0.0 3.4 3 1 0 3 3 3 0 RNA polymerase Rpb5, C-terminal domain Moulting_cycle PF04870.11 ETN99257.1 - 0.0043 16.1 0.7 0.0054 15.8 0.5 1.2 1 0 0 1 1 1 1 Moulting cycle DinB_2 PF12867.2 ETN99257.1 - 0.073 13.4 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 DinB superfamily DUF2457 PF10446.4 ETN99258.1 - 0.2 10.3 7.8 0.19 10.4 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Secretin_N_2 PF07655.8 ETN99258.1 - 0.62 10.4 7.8 0.93 9.9 5.4 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain RCR PF12273.3 ETN99258.1 - 0.68 10.5 3.3 0.93 10.0 2.3 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Herpes_LMP1 PF05297.6 ETN99258.1 - 1.3 7.8 13.3 1.3 7.8 9.3 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) NOA36 PF06524.7 ETN99258.1 - 3.5 6.8 7.4 3.5 6.8 5.1 1.2 1 0 0 1 1 1 0 NOA36 protein DSPc PF00782.15 ETN99260.1 - 8.5e-07 28.6 0.2 1.4e-06 27.8 0.1 1.5 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain PA14 PF07691.7 ETN99261.1 - 0.12 11.9 6.1 0.57 9.8 4.2 2.0 1 1 0 1 1 1 0 PA14 domain SOG2 PF10428.4 ETN99261.1 - 1.6 7.2 7.0 1.7 7.1 4.9 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Ras PF00071.17 ETN99262.1 - 5.3e-45 152.7 0.4 5.9e-45 152.5 0.3 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.16 ETN99262.1 - 9.6e-11 41.2 0.1 1e-10 41.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 ETN99262.1 - 1.1e-10 42.0 0.0 1.6e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 ETN99262.1 - 0.0068 15.8 0.0 0.0096 15.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 ETN99262.1 - 0.029 13.4 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region CLN3 PF02487.12 ETN99264.1 - 0.02 13.7 0.9 0.061 12.0 0.1 1.8 1 1 1 2 2 2 0 CLN3 protein NOT2_3_5 PF04153.13 ETN99264.1 - 0.74 9.6 6.3 0.28 11.0 0.5 2.1 2 0 0 2 2 2 0 NOT2 / NOT3 / NOT5 family DUF3671 PF12420.3 ETN99264.1 - 1 9.3 5.6 0.87 9.5 2.3 1.9 2 0 0 2 2 2 0 Protein of unknown function Nucleo_LEF-12 PF06256.6 ETN99266.1 - 0.057 13.1 0.6 0.086 12.6 0.5 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus LEF-12 protein Transket_pyr PF02779.19 ETN99267.1 - 9.7e-56 188.0 0.0 1.2e-55 187.7 0.0 1.1 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 ETN99267.1 - 0.041 12.5 0.1 0.063 11.9 0.1 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component WD40 PF00400.27 ETN99268.1 - 6.2e-09 35.4 2.7 9.9e-08 31.5 0.2 2.7 2 1 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETN99268.1 - 0.0042 15.3 0.0 0.0042 15.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin Nup120/160 WBP-1 PF11669.3 ETN99269.1 - 0.05 13.6 0.9 0.1 12.6 0.6 1.5 1 0 0 1 1 1 0 WW domain-binding protein 1 RE_LlaMI PF09562.5 ETN99270.1 - 0.038 13.1 0.1 0.05 12.7 0.1 1.3 1 1 0 1 1 1 0 LlaMI restriction endonuclease Actin PF00022.14 ETN99271.1 - 1.9e-17 62.8 0.0 2.1e-17 62.6 0.0 1.0 1 0 0 1 1 1 1 Actin DUF4041 PF13250.1 ETN99271.1 - 0.17 11.4 1.1 0.22 11.1 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) Actin PF00022.14 ETN99272.1 - 4.8e-09 35.1 0.1 5.1e-09 35.0 0.1 1.1 1 0 0 1 1 1 1 Actin zf-RING_2 PF13639.1 ETN99273.1 - 0.083 12.7 0.3 0.51 10.2 0.0 2.2 2 0 0 2 2 2 0 Ring finger domain DUF258 PF03193.11 ETN99274.1 - 8.3e-06 25.0 1.7 5.4e-05 22.4 0.1 2.7 2 1 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 ETN99274.1 - 4.6e-05 23.3 0.9 0.00011 22.1 0.1 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF815 PF05673.8 ETN99274.1 - 0.0011 17.9 0.0 0.002 17.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_PrkA PF08298.6 ETN99274.1 - 0.0023 16.6 0.1 0.0031 16.2 0.1 1.3 1 0 0 1 1 1 1 PrkA AAA domain Miro PF08477.8 ETN99274.1 - 0.0035 17.8 0.8 0.0078 16.7 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein DUF4171 PF13775.1 ETN99274.1 - 0.0057 16.8 1.7 0.013 15.6 1.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4171) ABC_tran PF00005.22 ETN99274.1 - 0.0063 16.8 0.2 0.0063 16.8 0.2 2.2 1 1 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 ETN99274.1 - 0.03 13.8 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.12 ETN99274.1 - 0.062 12.7 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 ETN99274.1 - 0.098 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 ETN99274.1 - 0.1 12.8 2.7 0.15 12.2 0.1 2.5 2 2 0 3 3 3 0 RNA helicase AAA_16 PF13191.1 ETN99274.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain S_layer_C PF05124.7 ETN99274.1 - 1.7 8.2 10.2 2.6 7.5 7.1 1.3 1 0 0 1 1 1 0 S-layer like family, C-terminal region Endonuclease_NS PF01223.18 ETN99275.1 - 6.9e-12 45.4 0.1 7.5e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease AAA_PrkA PF08298.6 ETN99279.1 - 0.021 13.5 0.3 0.021 13.5 0.2 1.4 2 0 0 2 2 2 0 PrkA AAA domain S-methyl_trans PF02574.11 ETN99280.1 - 0.019 14.2 0.5 0.023 13.9 0.4 1.0 1 0 0 1 1 1 0 Homocysteine S-methyltransferase DUF3373 PF11853.3 ETN99280.1 - 0.02 13.4 9.1 0.028 12.9 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) ResB PF05140.9 ETN99280.1 - 0.076 11.5 8.0 0.089 11.3 5.5 1.1 1 0 0 1 1 1 0 ResB-like family PAT1 PF09770.4 ETN99280.1 - 0.66 8.1 29.8 0.77 7.9 20.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2681 PF10883.3 ETN99280.1 - 0.8 9.9 26.9 0.18 12.0 1.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2681) DivIC PF04977.10 ETN99280.1 - 0.87 9.1 19.8 0.88 9.0 7.3 2.2 2 0 0 2 2 2 0 Septum formation initiator Ctr PF04145.10 ETN99280.1 - 0.95 9.5 5.9 1.5 8.8 4.1 1.4 1 1 0 1 1 1 0 Ctr copper transporter family IncA PF04156.9 ETN99280.1 - 1.5 8.4 14.8 2.9 7.4 5.5 2.1 2 0 0 2 2 2 0 IncA protein DUF106 PF01956.11 ETN99280.1 - 2.2 7.8 7.5 0.34 10.4 1.3 1.9 2 0 0 2 2 2 0 Integral membrane protein DUF106 PulG PF11773.3 ETN99280.1 - 2.3 8.0 13.9 2.6 7.8 0.7 2.2 2 0 0 2 2 2 0 Type II secretory pathway pseudopilin FliJ PF02050.11 ETN99280.1 - 3.5 7.7 30.2 8.3 6.4 21.0 1.5 1 1 0 1 1 1 0 Flagellar FliJ protein Oleosin PF01277.12 ETN99280.1 - 6.3 6.3 6.5 2.8 7.5 0.6 2.1 2 0 0 2 2 2 0 Oleosin RED_N PF07808.8 ETN99280.1 - 6.9 5.8 17.8 0.67 9.1 6.4 2.0 2 0 0 2 2 2 0 RED-like protein N-terminal region Activator_LAG-3 PF11498.3 ETN99280.1 - 10 4.7 37.3 12 4.4 25.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Microvir_H PF04687.7 ETN99281.1 - 0.033 13.2 0.1 0.034 13.1 0.1 1.0 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) DUF2508 PF10704.4 ETN99281.1 - 0.21 11.8 2.9 0.22 11.7 1.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2508) RBM39linker PF15519.1 ETN99284.1 - 0.0093 16.2 0.3 0.04 14.1 0.2 2.1 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein zf-CCHC_4 PF14392.1 ETN99284.1 - 0.39 10.4 7.0 11 5.8 0.0 2.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.18 ETN99284.1 - 5.9 7.0 15.7 2.7 8.0 2.0 2.8 2 0 0 2 2 2 0 Zinc knuckle Kelch_1 PF01344.20 ETN99286.1 - 5.6e-07 29.0 3.8 0.0089 15.5 0.5 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.1 ETN99286.1 - 7.3e-05 22.7 3.3 0.14 12.3 0.2 2.5 1 1 1 2 2 2 2 Kelch motif Kelch_2 PF07646.10 ETN99286.1 - 0.00016 21.3 1.4 0.7 9.7 0.2 3.1 3 1 0 3 3 3 2 Kelch motif Myco_haema PF05692.7 ETN99286.1 - 0.00083 18.1 2.8 0.00089 18.0 1.9 1.0 1 0 0 1 1 1 1 Mycoplasma haemagglutinin Kelch_4 PF13418.1 ETN99286.1 - 0.017 14.8 1.9 0.57 9.9 0.0 2.4 2 1 0 2 2 2 0 Galactose oxidase, central domain Kelch_5 PF13854.1 ETN99286.1 - 0.02 14.8 4.5 1.7 8.7 0.1 2.3 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.1 ETN99286.1 - 0.088 13.0 1.2 6.2 7.1 0.1 2.4 2 0 0 2 2 2 0 Galactose oxidase, central domain NACHT PF05729.7 ETN99287.1 - 2.3e-08 33.8 0.0 5e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETN99287.1 - 6.7e-05 23.1 0.2 6.7e-05 23.1 0.1 3.4 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 ETN99287.1 - 0.00015 21.8 0.0 0.00082 19.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ETN99287.1 - 0.0046 17.7 0.3 0.027 15.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETN99287.1 - 0.047 13.6 0.2 0.37 10.7 0.0 2.3 1 1 1 2 2 2 0 AAA ATPase domain AAA PF00004.24 ETN99287.1 - 0.061 13.5 0.0 0.21 11.7 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HHH_2 PF12826.2 ETN99287.1 - 0.37 10.7 2.6 21 5.0 0.2 3.3 3 0 0 3 3 3 0 Helix-hairpin-helix motif RNA_helicase PF00910.17 ETN99287.1 - 0.63 10.2 0.0 0.63 10.2 0.0 3.7 4 0 0 4 4 4 0 RNA helicase HEAT PF02985.17 ETN99289.1 - 0.014 15.4 0.0 0.067 13.3 0.0 2.1 2 0 0 2 2 2 0 HEAT repeat HEAT_2 PF13646.1 ETN99289.1 - 0.014 15.6 0.0 0.015 15.5 0.0 1.2 1 0 0 1 1 1 0 HEAT repeats HEAT_EZ PF13513.1 ETN99289.1 - 0.14 12.7 0.0 0.28 11.7 0.0 1.6 1 1 0 1 1 1 0 HEAT-like repeat HemY_N PF07219.8 ETN99290.1 - 1.5 8.4 8.1 3.2 7.3 0.2 2.5 2 1 0 2 2 2 0 HemY protein N-terminus ENTH PF01417.15 ETN99291.1 - 0.0041 16.9 0.0 0.0089 15.8 0.0 1.6 1 0 0 1 1 1 1 ENTH domain Cyclin PF08613.6 ETN99291.1 - 0.035 14.4 0.2 0.076 13.4 0.1 1.5 1 1 0 1 1 1 0 Cyclin OMPdecase PF00215.19 ETN99292.1 - 4.4e-69 232.3 0.0 7e-69 231.6 0.0 1.3 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.22 ETN99292.1 - 4.6e-11 42.5 0.0 1.1e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Rep_fac_C PF08542.6 ETN99293.1 - 3.3e-11 43.0 0.1 7.1e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 ETN99293.1 - 2.2e-10 40.4 0.0 4.2e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 ETN99293.1 - 8.8e-06 25.9 0.0 2.1e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.8 ETN99293.1 - 0.023 14.2 0.0 0.044 13.2 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III, delta subunit SNF2_N PF00176.18 ETN99293.1 - 0.062 12.0 0.0 0.098 11.4 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_22 PF13401.1 ETN99293.1 - 0.066 13.3 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain mRNA_cap_enzyme PF01331.14 ETN99295.1 - 0.0058 16.3 0.6 1.6 8.3 0.1 2.3 2 1 0 2 2 2 2 mRNA capping enzyme, catalytic domain Baculo_ODV-E27 PF05314.6 ETN99295.1 - 0.033 13.2 1.6 0.59 9.1 0.5 2.1 2 0 0 2 2 2 0 Baculovirus occlusion-derived virus envelope protein EC27 NDUF_B6 PF09782.4 ETN99296.1 - 0.19 11.5 0.9 0.28 11.0 0.6 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit WD40 PF00400.27 ETN99298.1 - 6e-15 54.4 5.6 1.1e-10 40.9 0.0 3.4 3 1 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN99298.1 - 0.033 12.3 0.1 0.093 10.8 0.0 1.8 1 1 1 2 2 2 0 Nucleoporin Nup120/160 HAD PF12710.2 ETN99298.1 - 0.12 12.5 0.1 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase FRG PF08867.6 ETN99299.1 - 0.023 15.1 0.2 0.043 14.3 0.2 1.4 1 0 0 1 1 1 0 FRG domain YecM PF06185.7 ETN99300.1 - 0.076 12.2 0.2 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 YecM protein DUF3617 PF12276.3 ETN99300.1 - 0.099 12.0 5.6 0.041 13.3 2.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3617) FerI PF08151.7 ETN99300.1 - 5 7.2 5.6 1.8 8.6 0.1 2.3 2 1 0 2 2 2 0 FerI (NUC094) domain HEAT_2 PF13646.1 ETN99301.1 - 0.0056 16.9 0.0 0.21 11.8 0.0 2.9 2 1 1 3 3 3 1 HEAT repeats HEAT_EZ PF13513.1 ETN99301.1 - 0.0075 16.7 0.1 26 5.4 0.0 3.9 4 0 0 4 4 4 1 HEAT-like repeat Peptidase_C14 PF00656.17 ETN99302.1 - 0.00011 22.0 0.1 0.00026 20.7 0.0 1.6 1 1 0 1 1 1 1 Caspase domain DUF2540 PF10802.3 ETN99304.1 - 0.19 11.4 2.8 0.22 11.2 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2540) SATase_N PF06426.9 ETN99305.1 - 0.011 16.0 1.1 0.012 15.8 0.7 1.1 1 0 0 1 1 1 0 Serine acetyltransferase, N-terminal Pox_A6 PF04924.7 ETN99305.1 - 0.012 14.4 3.3 0.013 14.3 2.3 1.0 1 0 0 1 1 1 0 Poxvirus A6 protein AHS1 PF02682.11 ETN99305.1 - 0.028 13.8 1.1 0.031 13.7 0.8 1.0 1 0 0 1 1 1 0 Allophanate hydrolase subunit 1 RolB_RolC PF02027.12 ETN99305.1 - 0.051 12.7 1.3 0.061 12.4 0.9 1.1 1 0 0 1 1 1 0 RolB/RolC glucosidase family Syntaxin_2 PF14523.1 ETN99305.1 - 0.065 13.2 8.8 0.081 12.9 6.1 1.1 1 0 0 1 1 1 0 Syntaxin-like protein Sipho_Gp157 PF05565.6 ETN99305.1 - 0.09 12.3 6.8 0.1 12.1 4.7 1.1 1 0 0 1 1 1 0 Siphovirus Gp157 Y2_Tnp PF04986.8 ETN99305.1 - 0.09 12.5 0.2 0.1 12.3 0.1 1.1 1 0 0 1 1 1 0 Putative transposase IL15 PF02372.10 ETN99305.1 - 0.098 12.4 3.6 0.15 11.8 2.5 1.4 1 1 0 1 1 1 0 Interleukin 15 IncA PF04156.9 ETN99305.1 - 0.34 10.4 13.7 0.41 10.2 9.5 1.0 1 0 0 1 1 1 0 IncA protein HrpJ PF07201.6 ETN99305.1 - 0.4 10.6 9.0 0.5 10.3 6.2 1.1 1 0 0 1 1 1 0 HrpJ-like domain Atg14 PF10186.4 ETN99305.1 - 0.82 8.5 8.6 0.93 8.3 5.9 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SPATA24 PF15175.1 ETN99305.1 - 0.84 9.3 13.0 4.3 7.0 4.5 2.0 1 1 1 2 2 2 0 Spermatogenesis-associated protein 24 Exonuc_VII_L PF02601.10 ETN99305.1 - 1.2 8.2 8.4 1.4 8.0 5.8 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_32 PF13654.1 ETN99305.1 - 1.2 7.6 8.0 1.3 7.5 5.5 1.0 1 0 0 1 1 1 0 AAA domain DUF3573 PF12097.3 ETN99305.1 - 2.8 6.4 8.4 2.8 6.4 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) MerR-DNA-bind PF09278.6 ETN99305.1 - 3.4 8.1 6.2 5.1 7.5 1.2 2.2 2 0 0 2 2 2 0 MerR, DNA binding V_ATPase_I PF01496.14 ETN99305.1 - 3.5 5.3 9.3 3.6 5.3 6.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CRT10 PF08728.5 ETN99306.1 - 0.43 8.5 13.1 0.46 8.4 9.1 1.0 1 0 0 1 1 1 0 CRT10 DUF2956 PF11169.3 ETN99307.1 - 6.2 6.8 9.6 1.6 8.7 4.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) WD40 PF00400.27 ETN99308.1 - 1.1e-49 164.5 13.1 3e-16 58.5 0.0 5.5 5 1 1 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 ETN99308.1 - 4.5e-07 29.7 0.0 0.001 18.8 0.0 2.2 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETN99308.1 - 3.3e-06 25.5 0.7 0.03 12.4 0.0 3.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETN99308.1 - 4e-06 26.4 0.7 0.00094 18.7 0.1 2.2 1 1 1 2 2 2 2 PQQ-like domain PD40 PF07676.7 ETN99308.1 - 0.00024 20.6 2.5 5.1 6.8 0.1 3.5 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETN99308.1 - 0.00048 18.5 0.1 0.57 8.4 0.0 2.9 1 1 2 3 3 3 2 Cytochrome D1 heme domain DUF1258 PF06869.7 ETN99308.1 - 0.00055 19.1 0.0 0.29 10.1 0.0 3.2 1 1 3 4 4 4 1 Protein of unknown function (DUF1258) Proteasome_A_N PF10584.4 ETN99308.1 - 0.0059 15.9 2.4 14 5.0 0.0 3.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature DUF1136 PF06582.7 ETN99308.1 - 0.014 15.0 0.4 48 3.7 0.0 4.0 4 0 0 4 4 4 0 Repeat of unknown function (DUF1136) PQQ PF01011.16 ETN99308.1 - 0.063 12.8 0.0 10 5.8 0.0 3.4 4 0 0 4 4 4 0 PQQ enzyme repeat PQQ_3 PF13570.1 ETN99308.1 - 0.07 13.4 0.0 29 5.1 0.0 3.0 2 1 1 3 3 3 0 PQQ-like domain DUF3312 PF11768.3 ETN99308.1 - 0.071 11.3 0.0 16 3.5 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3312) PLD_C PF12357.3 ETN99308.1 - 0.073 12.6 0.3 96 2.6 0.0 4.0 2 1 1 4 4 4 0 Phospholipase D C terminal NYD-SP28_assoc PF14775.1 ETN99308.1 - 0.13 11.9 0.3 14 5.4 0.0 3.3 4 0 0 4 4 4 0 Sperm tail C-terminal domain PDEase_I PF00233.14 ETN99309.1 - 0.036 13.8 0.2 0.061 13.0 0.1 1.5 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase Pollen_allerg_2 PF01620.11 ETN99309.1 - 0.19 12.0 1.2 0.34 11.2 0.8 1.5 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) LELP1 PF15042.1 ETN99311.1 - 0.0058 16.8 1.5 0.0084 16.2 1.0 1.2 1 0 0 1 1 1 1 Late cornified envelope-like proline-rich protein 1 Aha1_N PF09229.6 ETN99311.1 - 0.28 11.0 4.9 0.34 10.7 3.4 1.1 1 0 0 1 1 1 0 Activator of Hsp90 ATPase, N-terminal PDEase_I PF00233.14 ETN99312.1 - 1.5e-61 208.2 0.0 4.9e-35 121.3 0.0 2.1 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase CDC45 PF02724.9 ETN99312.1 - 0.025 12.6 1.6 0.035 12.1 1.1 1.2 1 0 0 1 1 1 0 CDC45-like protein HD PF01966.17 ETN99312.1 - 0.047 13.6 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 HD domain Sigma70_ner PF04546.8 ETN99312.1 - 0.075 12.6 3.5 0.13 11.8 2.4 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.4 ETN99312.1 - 1.2 7.8 12.9 1.6 7.3 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 ETN99312.1 - 6.9 5.8 8.1 13 4.9 5.6 1.4 1 0 0 1 1 1 0 NOA36 protein SAM_1 PF00536.25 ETN99313.1 - 2.9e-05 24.1 0.1 0.11 12.7 0.0 2.7 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETN99313.1 - 0.0013 18.4 0.1 0.5 10.2 0.0 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) NCD1 PF04904.8 ETN99313.1 - 0.0017 18.0 0.2 0.0039 16.9 0.1 1.6 1 1 0 1 1 1 1 NAB conserved region 1 (NCD1) DUF2935 PF11155.3 ETN99313.1 - 0.19 11.8 1.9 0.3 11.1 1.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) XkdN PF08890.6 ETN99313.1 - 0.21 11.3 5.6 1.7 8.4 0.2 2.2 1 1 1 2 2 2 0 Phage XkdN-like protein PUB PF09409.5 ETN99315.1 - 0.00018 21.1 1.5 0.00089 18.9 1.0 2.0 1 1 0 1 1 1 1 PUB domain SPG48 PF14764.1 ETN99315.1 - 0.031 12.7 0.1 0.048 12.1 0.1 1.4 1 1 0 1 1 1 0 AP-5 complex subunit, vesicle trafficking UPF0122 PF04297.9 ETN99315.1 - 0.41 10.6 3.4 0.3 11.1 0.6 2.1 1 1 1 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like LAGLIDADG_1 PF00961.14 ETN99315.1 - 2.4 8.7 5.8 2.1 8.9 0.3 1.9 1 1 1 2 2 2 0 LAGLIDADG endonuclease WD40 PF00400.27 ETN99316.1 - 9.4e-27 91.8 9.3 6.3e-11 41.7 0.1 4.0 4 1 0 4 4 4 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETN99316.1 - 0.00046 19.0 3.7 0.042 12.5 2.6 2.3 1 1 0 1 1 1 1 Nup133 N terminal like Nup160 PF11715.3 ETN99316.1 - 0.0027 15.9 0.0 0.48 8.4 0.0 2.7 1 1 1 3 3 3 2 Nucleoporin Nup120/160 HAD PF12710.2 ETN99316.1 - 0.07 13.2 0.2 0.11 12.6 0.1 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase TetM_leader PF08076.6 ETN99316.1 - 0.6 9.7 6.3 0.86 9.2 0.2 2.9 3 0 0 3 3 3 0 Tetracycline resistance determinant leader peptide WD40 PF00400.27 ETN99318.1 - 5.5e-16 57.7 4.8 4.7e-05 23.1 0.0 4.2 3 1 0 3 3 3 3 WD domain, G-beta repeat RE_MjaI PF09568.5 ETN99318.1 - 0.0034 16.9 0.2 0.0044 16.5 0.1 1.1 1 0 0 1 1 1 1 MjaI restriction endonuclease RasGEF_N PF00618.15 ETN99318.1 - 0.01 15.9 0.1 0.014 15.5 0.1 1.3 1 0 0 1 1 1 0 RasGEF N-terminal motif Vma12 PF11712.3 ETN99319.1 - 0.11 12.1 0.1 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2393 PF09624.5 ETN99319.1 - 1.1 8.7 4.5 1.6 8.2 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) POX PF07526.6 ETN99320.1 - 0.13 12.5 2.3 0.18 12.0 1.6 1.3 1 0 0 1 1 1 0 Associated with HOX Pex14_N PF04695.8 ETN99320.1 - 0.13 12.2 3.9 0.19 11.7 2.7 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region LHH PF14411.1 ETN99320.1 - 0.14 12.4 11.7 0.51 10.6 5.8 2.2 2 0 0 2 2 2 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH Zip PF02535.17 ETN99320.1 - 0.23 10.4 4.7 0.23 10.4 3.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF605 PF04652.11 ETN99320.1 - 0.98 8.7 9.9 1 8.6 6.8 1.1 1 0 0 1 1 1 0 Vta1 like DUF912 PF06024.7 ETN99320.1 - 1.1 9.3 9.2 2.2 8.4 6.4 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Macoilin PF09726.4 ETN99320.1 - 2.1 6.5 8.9 2.1 6.5 6.2 1.1 1 0 0 1 1 1 0 Transmembrane protein RP-C_C PF11800.3 ETN99320.1 - 3 7.5 5.0 3.7 7.1 3.5 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Menin PF05053.8 ETN99320.1 - 5.8 4.9 10.2 6.8 4.7 7.1 1.1 1 0 0 1 1 1 0 Menin TPR_11 PF13414.1 ETN99321.1 - 3.5e-07 29.7 2.7 1.1e-05 24.9 0.2 2.5 1 1 1 2 2 2 1 TPR repeat TPR_8 PF13181.1 ETN99321.1 - 0.00019 20.9 2.8 0.36 10.7 0.1 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETN99321.1 - 0.00038 21.0 0.2 0.00099 19.7 0.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETN99321.1 - 0.00047 20.0 3.3 0.0038 17.1 1.5 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETN99321.1 - 0.0011 18.4 3.5 0.41 10.3 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETN99321.1 - 0.0076 16.5 1.3 0.021 15.1 0.2 2.1 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETN99321.1 - 0.029 14.9 0.1 0.37 11.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETN99321.1 - 0.089 12.7 3.0 2.4 8.2 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Trypan_PARP PF05887.6 ETN99321.1 - 2.5 7.8 34.2 0.13 12.1 16.0 2.7 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Intimin_C PF07979.6 ETN99322.1 - 0.032 14.4 0.1 0.081 13.1 0.1 1.6 1 0 0 1 1 1 0 Intimin C-type lectin domain Di19_C PF14571.1 ETN99322.1 - 4.4 7.6 13.2 0.054 13.8 1.5 2.5 1 1 0 2 2 2 0 Stress-induced protein Di19, C-terminal DNA_pol3_tau_4 PF12168.3 ETN99324.1 - 0.23 11.8 4.8 0.35 11.2 3.3 1.3 1 0 0 1 1 1 0 DNA polymerase III subunits tau domain IV DnaB-binding DUF3752 PF12572.3 ETN99324.1 - 0.33 11.0 4.6 0.41 10.7 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) DUF1628 PF07790.6 ETN99324.1 - 0.47 11.2 0.2 0.47 11.2 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1628) Peptidase_M1 PF01433.15 ETN99325.1 - 2.6e-52 178.2 0.1 1.6e-46 159.1 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M1 Peptidase_MA_2 PF13485.1 ETN99325.1 - 1.2e-08 35.0 0.0 2.3e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Glyco_transf_22 PF03901.12 ETN99327.1 - 0.00079 18.5 4.9 0.00079 18.5 3.4 1.8 3 0 0 3 3 3 1 Alg9-like mannosyltransferase family Glyco_transf_22 PF03901.12 ETN99328.1 - 1.7e-16 60.2 23.5 2.9e-10 39.7 5.9 3.1 2 1 1 3 3 3 2 Alg9-like mannosyltransferase family Phage_CII PF05269.6 ETN99332.1 - 0.018 15.0 1.3 1.2 9.1 0.1 2.2 2 0 0 2 2 2 0 Bacteriophage CII protein L27_2 PF09045.5 ETN99332.1 - 0.092 12.3 1.4 0.18 11.3 1.0 1.5 1 0 0 1 1 1 0 L27_2 NACHT PF05729.7 ETN99333.1 - 1.7e-10 40.8 0.0 3.2e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETN99333.1 - 3.4e-05 24.1 1.6 8.3e-05 22.8 0.0 2.5 3 0 0 3 3 3 1 AAA domain ATP_bind_2 PF03668.10 ETN99333.1 - 7.9e-05 21.8 0.0 0.00016 20.9 0.0 1.4 1 0 0 1 1 1 1 P-loop ATPase protein family AAA_22 PF13401.1 ETN99333.1 - 0.00058 20.0 0.0 0.0019 18.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETN99333.1 - 0.00085 20.1 0.1 0.0048 17.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 ETN99333.1 - 0.037 13.6 0.0 0.18 11.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 ETN99333.1 - 0.072 12.6 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 ETN99333.1 - 0.3 11.3 5.4 0.25 11.6 2.1 2.1 2 1 0 2 2 2 0 ABC transporter RelA_SpoT PF04607.12 ETN99334.1 - 0.00072 19.5 1.1 0.002 18.1 0.1 2.1 2 0 0 2 2 2 1 Region found in RelA / SpoT proteins ATP-cone PF03477.11 ETN99334.1 - 0.01 16.2 0.8 1.5 9.3 0.1 2.4 2 0 0 2 2 2 0 ATP cone domain DUF3463 PF11946.3 ETN99334.1 - 0.031 13.8 0.6 0.056 13.0 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3463) Med10 PF09748.4 ETN99334.1 - 0.1 12.3 0.9 0.71 9.6 0.6 2.2 1 1 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex Tropomodulin PF03250.9 ETN99334.1 - 0.19 11.2 1.1 0.59 9.6 0.1 2.1 2 1 0 2 2 2 0 Tropomodulin OmpH PF03938.9 ETN99334.1 - 0.37 10.7 2.1 4.9 7.0 0.0 2.3 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Sipho_Gp157 PF05565.6 ETN99334.1 - 0.49 9.9 5.5 2.7 7.5 0.2 2.6 3 0 0 3 3 3 0 Siphovirus Gp157 Drc1-Sld2 PF11719.3 ETN99335.1 - 0.12 11.4 19.5 0.15 11.1 13.5 1.0 1 0 0 1 1 1 0 DNA replication and checkpoint protein DUF2481 PF10654.4 ETN99335.1 - 0.41 10.3 9.7 0.36 10.5 5.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2481) BCL_N PF04714.8 ETN99335.1 - 1.4 8.5 5.7 14 5.3 0.3 3.0 3 0 0 3 3 3 0 BCL7, N-terminal conserver region Exonuc_VII_L PF02601.10 ETN99335.1 - 3.4 6.7 18.6 4.5 6.3 12.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit YjcZ PF13990.1 ETN99335.1 - 6.7 5.7 11.5 0.74 8.8 0.5 2.1 1 1 1 2 2 2 0 YjcZ-like protein ETF_QO PF05187.8 ETN99335.1 - 8.6 6.4 8.2 0.95 9.4 1.9 2.1 1 1 0 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase Peptidase_C14 PF00656.17 ETN99336.1 - 7.6e-13 48.7 0.3 7.8e-13 48.6 0.2 1.0 1 0 0 1 1 1 1 Caspase domain Guanylate_cyc_2 PF09778.4 ETN99336.1 - 0.013 14.7 0.1 0.015 14.4 0.1 1.1 1 0 0 1 1 1 0 Guanylylate cyclase UCH PF00443.24 ETN99336.1 - 0.037 13.1 0.1 0.044 12.8 0.0 1.0 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Pro_3_hydrox_C PF05373.6 ETN99336.1 - 0.086 12.8 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal DNA_pol3_delta2 PF13177.1 ETN99336.1 - 0.11 12.1 0.4 0.15 11.6 0.3 1.3 1 1 0 1 1 1 0 DNA polymerase III, delta subunit TPR_12 PF13424.1 ETN99337.1 - 7.5e-191 618.5 58.2 8.5e-21 73.6 0.4 12.4 6 2 4 12 12 12 12 Tetratricopeptide repeat TPR_10 PF13374.1 ETN99337.1 - 7.1e-115 372.1 0.0 2e-07 30.6 0.0 19.8 18 2 2 20 20 20 16 Tetratricopeptide repeat TPR_1 PF00515.23 ETN99337.1 - 2.7e-109 352.7 145.6 1.5e-08 33.8 0.8 20.3 19 1 1 20 20 20 19 Tetratricopeptide repeat TPR_11 PF13414.1 ETN99337.1 - 9.2e-101 329.5 152.3 2.7e-12 46.1 2.4 14.2 5 4 10 15 15 15 15 TPR repeat TPR_7 PF13176.1 ETN99337.1 - 3.9e-97 310.5 64.1 1.1e-06 28.0 0.1 20.2 18 1 2 20 20 20 18 Tetratricopeptide repeat TPR_2 PF07719.12 ETN99337.1 - 8.1e-90 287.6 116.8 3.2e-07 29.7 0.4 20.2 18 1 2 20 20 20 18 Tetratricopeptide repeat TPR_8 PF13181.1 ETN99337.1 - 1.3e-70 227.9 155.1 2e-06 27.1 1.8 20.1 18 1 2 20 20 20 18 Tetratricopeptide repeat TPR_16 PF13432.1 ETN99337.1 - 1.2e-39 134.1 11.4 0.00087 19.8 0.0 14.5 4 3 11 15 15 15 9 Tetratricopeptide repeat TPR_17 PF13431.1 ETN99337.1 - 2.9e-39 129.9 41.7 0.0077 16.3 0.0 19.6 19 1 0 19 19 19 11 Tetratricopeptide repeat TPR_6 PF13174.1 ETN99337.1 - 1.1e-33 113.3 35.4 0.017 15.5 0.0 15.9 15 1 1 16 16 16 9 Tetratricopeptide repeat TPR_14 PF13428.1 ETN99337.1 - 2.8e-30 102.0 2.1 0.28 11.9 0.0 16.7 15 3 3 19 19 16 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETN99337.1 - 8.1e-11 42.1 25.5 0.92 9.8 0.0 11.4 6 4 6 12 12 12 3 Tetratricopeptide repeat Ten1_2 PF15490.1 ETN99337.1 - 9.5e-07 28.4 1.2 23 4.6 0.0 7.5 5 3 2 8 8 8 0 Telomere-capping, CST complex subunit TPR_9 PF13371.1 ETN99337.1 - 2.9e-06 27.0 2.1 3.1 7.7 0.1 7.2 7 1 1 8 8 7 1 Tetratricopeptide repeat POR PF01558.13 ETN99337.1 - 5e-06 26.5 6.0 0.036 13.9 0.1 5.6 4 3 1 5 5 5 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PPR PF01535.15 ETN99337.1 - 1.9e-05 24.2 63.3 2.6 8.2 0.1 16.8 18 1 1 19 19 18 2 PPR repeat GST_C_3 PF14497.1 ETN99337.1 - 2.5e-05 24.6 6.7 8.1 6.9 0.0 7.2 7 0 0 7 7 7 0 Glutathione S-transferase, C-terminal domain TPR_3 PF07720.7 ETN99337.1 - 7.6e-05 22.4 54.5 0.0043 16.8 1.8 11.4 12 0 0 12 12 12 3 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETN99337.1 - 0.0018 17.4 20.6 0.02 14.1 0.0 9.3 13 0 0 13 13 11 1 SHNi-TPR Syntaxin_2 PF14523.1 ETN99337.1 - 0.0035 17.3 9.4 32 4.6 0.0 8.1 7 4 2 10 10 9 0 Syntaxin-like protein Mob_Pre PF01076.14 ETN99337.1 - 0.032 13.8 38.5 0.47 10.0 0.4 6.8 2 2 5 7 7 7 0 Plasmid recombination enzyme Rapsyn_N PF10579.4 ETN99337.1 - 0.035 13.8 23.8 7.1 6.5 0.0 9.0 9 2 1 10 10 10 0 Rapsyn N-terminal myristoylation and linker region Ubiq-assoc PF09145.5 ETN99337.1 - 0.082 12.7 45.6 0.12 12.2 0.2 14.0 11 4 5 16 16 16 0 Ubiquitin-associated ANKH PF07260.6 ETN99337.1 - 0.21 10.5 3.4 65 2.3 0.0 4.9 5 1 0 5 5 5 0 Progressive ankylosis protein (ANKH) STIL_N PF15253.1 ETN99337.1 - 0.32 9.6 0.1 67 2.0 0.0 3.2 4 0 0 4 4 4 0 SCL-interrupting locus protein N-terminus Tektin PF03148.9 ETN99337.1 - 1.1 7.7 6.9 3.5 6.0 0.0 3.9 5 0 0 5 5 5 0 Tektin family DUF912 PF06024.7 ETN99339.1 - 0.001 19.0 1.0 0.0015 18.5 0.7 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) HlyD_2 PF12700.2 ETN99339.1 - 0.022 13.9 4.3 0.026 13.6 3.0 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Pex14_N PF04695.8 ETN99339.1 - 0.038 14.0 4.1 0.061 13.3 2.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1793 PF08760.6 ETN99339.1 - 0.051 13.4 2.2 0.072 12.9 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1793) GBP_C PF02841.9 ETN99340.1 - 0.011 14.9 6.0 0.012 14.7 4.1 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF4557 PF15101.1 ETN99340.1 - 0.031 14.1 1.5 0.038 13.8 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) ArfGap PF01412.13 ETN99340.1 - 1.9 8.3 4.6 1.7 8.4 2.3 1.6 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf Daxx PF03344.10 ETN99342.1 - 0.00012 20.7 41.3 0.00016 20.3 28.6 1.1 1 0 0 1 1 1 1 Daxx Family Adap_comp_sub PF00928.16 ETN99343.1 - 1.8e-50 171.5 0.8 2.3e-50 171.1 0.5 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Ribosomal_L13 PF00572.13 ETN99343.1 - 0.071 13.1 0.1 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L13 Choline_sulf_C PF12411.3 ETN99345.1 - 0.027 14.2 0.1 0.096 12.5 0.0 1.8 2 0 0 2 2 2 0 Choline sulfatase enzyme C terminal Apc4_WD40 PF12894.2 ETN99346.1 - 0.00057 19.3 0.0 0.00096 18.6 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.27 ETN99346.1 - 0.025 14.4 0.0 0.29 11.1 0.0 2.1 2 0 0 2 2 2 0 WD domain, G-beta repeat DPPIV_N PF00930.16 ETN99346.1 - 0.14 10.6 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region WD40 PF00400.27 ETN99347.1 - 1.4e-10 40.5 11.1 6.6e-08 32.1 0.1 4.2 5 1 0 5 5 5 2 WD domain, G-beta repeat Nup160 PF11715.3 ETN99347.1 - 0.0015 16.7 0.2 0.0027 15.9 0.1 1.4 1 1 0 1 1 1 1 Nucleoporin Nup120/160 eIF2A PF08662.6 ETN99347.1 - 0.032 13.9 0.5 0.08 12.6 0.1 1.8 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Glyco_hydro_12 PF01670.11 ETN99347.1 - 0.12 12.2 0.6 0.15 11.8 0.1 1.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 12 WD40 PF00400.27 ETN99348.1 - 3.5e-25 86.8 10.6 3.8e-12 45.6 0.1 3.4 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN99348.1 - 9.9e-06 23.9 1.1 0.031 12.4 0.1 3.0 1 1 1 3 3 3 3 Nucleoporin Nup120/160 TetM_leader PF08076.6 ETN99348.1 - 0.46 10.0 3.9 15 5.2 0.1 3.2 3 0 0 3 3 3 0 Tetracycline resistance determinant leader peptide Mononeg_RNA_pol PF00946.14 ETN99349.1 - 0.097 10.0 1.7 0.1 9.9 1.2 1.0 1 0 0 1 1 1 0 Mononegavirales RNA dependent RNA polymerase DUF1410 PF07198.6 ETN99350.1 - 0.33 11.3 2.0 0.39 11.0 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1410) Guanylate_cyc PF00211.15 ETN99351.1 - 3.7e-19 68.8 0.3 7e-19 67.8 0.2 1.4 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain zf-RanBP PF00641.13 ETN99352.1 - 0.00088 18.3 0.4 0.0014 17.6 0.3 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.10 ETN99352.1 - 0.016 14.7 0.3 0.03 13.8 0.2 1.4 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Ydc2-catalyt PF09159.5 ETN99352.1 - 0.03 13.8 1.9 0.038 13.4 1.3 1.1 1 0 0 1 1 1 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 MIT PF04212.13 ETN99353.1 - 0.056 13.3 0.9 0.12 12.2 0.1 1.8 1 1 1 2 2 2 0 MIT (microtubule interacting and transport) domain DUF3161 PF11362.3 ETN99355.1 - 0.002 17.9 0.1 0.0032 17.3 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3161) DUF3819 PF12842.2 ETN99355.1 - 0.062 12.9 0.8 0.11 12.1 0.5 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3819) DUF2841 PF11001.3 ETN99356.1 - 0.15 11.9 1.0 0.2 11.5 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2841) DUF16 PF01519.11 ETN99356.1 - 0.66 10.2 4.5 0.92 9.7 3.1 1.3 1 1 0 1 1 1 0 Protein of unknown function DUF16 GPS PF01825.16 ETN99357.1 - 0.015 15.3 1.0 0.015 15.3 0.7 2.3 2 0 0 2 2 2 0 Latrophilin/CL-1-like GPS domain Pyr_redox_dim PF02852.17 ETN99358.1 - 0.22 11.5 1.1 7.5 6.6 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Cut8_N PF14482.1 ETN99358.1 - 4.4 7.3 7.6 9.3e+02 -0.1 5.3 3.0 1 1 0 1 1 1 0 Cut8 proteasome-binding domain Sec8_exocyst PF04048.9 ETN99360.1 - 0.0067 16.0 2.3 0.0067 16.0 1.6 1.8 1 1 1 2 2 2 1 Sec8 exocyst complex component specific domain DUF4179 PF13786.1 ETN99360.1 - 0.039 14.1 0.3 0.039 14.1 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4179) DUF489 PF04356.7 ETN99360.1 - 0.15 11.6 2.8 0.15 11.6 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF489) DUF4164 PF13747.1 ETN99360.1 - 0.71 10.0 9.7 2.9 8.0 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) MMtag PF10159.4 ETN99360.1 - 1.4 9.0 6.0 1.1 9.2 0.5 2.2 2 0 0 2 2 2 0 Kinase phosphorylation protein Tox-ODYAM1 PF15642.1 ETN99360.1 - 1.9 7.0 11.4 0.095 11.3 2.5 1.9 2 0 0 2 2 2 0 Toxin in Odyssella and Amoebophilus Syntaxin PF00804.20 ETN99360.1 - 3.1 8.0 15.1 0.25 11.5 4.4 2.1 1 1 1 2 2 2 0 Syntaxin NYD-SP28_assoc PF14775.1 ETN99360.1 - 5.8 6.6 9.1 11 5.7 0.3 3.0 2 2 1 3 3 3 0 Sperm tail C-terminal domain bZIP_Maf PF03131.12 ETN99360.1 - 6.2 7.1 16.0 0.31 11.3 2.7 2.4 2 1 0 2 2 2 0 bZIP Maf transcription factor HSCB_C PF07743.8 ETN99360.1 - 7.6 7.0 9.4 0.37 11.2 1.9 2.1 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain Ax_dynein_light PF10211.4 ETN99360.1 - 9 6.0 17.0 1.2 8.9 5.0 2.0 2 0 0 2 2 2 0 Axonemal dynein light chain HEAT PF02985.17 ETN99361.1 - 6.3e-12 44.5 0.0 0.02 14.9 0.0 6.4 6 0 0 6 6 6 3 HEAT repeat Ank_4 PF13637.1 ETN99361.1 - 2.2e-07 31.2 0.1 1.7e-06 28.3 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETN99361.1 - 2.2e-07 30.4 0.1 1.6e-05 24.7 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeat HEAT_2 PF13646.1 ETN99361.1 - 3.1e-07 30.5 0.0 0.058 13.6 0.0 3.8 2 2 2 4 4 4 3 HEAT repeats Ank_2 PF12796.2 ETN99361.1 - 5.9e-06 26.5 0.0 4.3e-05 23.7 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETN99361.1 - 1.5e-05 24.5 0.0 8e-05 22.2 0.0 2.4 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.1 ETN99361.1 - 3.3e-05 23.9 0.0 0.00025 21.1 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF2435 PF10363.4 ETN99361.1 - 0.024 14.5 6.8 5 7.0 0.1 4.7 3 1 1 4 4 4 0 Protein of unknown function (DUF2435) DNA_pol3_gamma3 PF12169.3 ETN99361.1 - 0.048 13.4 0.3 25 4.5 0.0 3.6 3 0 0 3 3 3 0 DNA polymerase III subunits gamma and tau domain III CSTF2_hinge PF14327.1 ETN99361.1 - 1.7 8.7 9.4 3.2 7.9 0.0 4.2 4 0 0 4 4 4 0 Hinge domain of cleavage stimulation factor subunit 2 HEAT_2 PF13646.1 ETN99362.1 - 6.8e-11 42.3 0.0 0.00013 22.1 0.0 5.4 3 1 4 7 7 7 2 HEAT repeats HEAT PF02985.17 ETN99362.1 - 2.2e-08 33.4 0.0 0.34 11.1 0.0 7.0 8 0 0 8 8 8 1 HEAT repeat HEAT_EZ PF13513.1 ETN99362.1 - 0.00084 19.7 0.0 1.3 9.6 0.0 4.8 4 1 1 5 5 5 2 HEAT-like repeat CRM1_C PF08767.6 ETN99362.1 - 0.011 14.6 33.7 0.19 10.6 0.6 6.0 1 1 5 6 6 6 0 CRM1 C terminal Lig_chan-Glu_bd PF10613.4 ETN99362.1 - 0.014 15.3 0.7 0.64 10.0 0.0 3.1 3 0 0 3 3 3 0 Ligated ion channel L-glutamate- and glycine-binding site Imm16 PF15565.1 ETN99362.1 - 0.039 13.7 7.1 4.7 7.1 0.1 4.5 2 1 4 6 6 6 0 Immunity protein 16 DUF4508 PF14969.1 ETN99362.1 - 1.4 8.9 14.0 1.4 8.9 0.2 4.6 4 2 1 5 5 5 0 Domain of unknown function (DUF4508) DUF2435 PF10363.4 ETN99362.1 - 4 7.4 21.0 1.6 8.6 0.2 6.1 5 1 1 6 6 6 0 Protein of unknown function (DUF2435) Tbf5 PF06331.7 ETN99362.1 - 5.3 6.8 12.2 1.2 8.9 0.2 4.7 4 0 0 4 4 4 0 Transcription factor TFIIH complex subunit Tfb5 Myb_DNA-bind_3 PF12776.2 ETN99362.1 - 8 7.1 17.8 14 6.4 0.0 5.7 3 3 1 5 5 5 0 Myb/SANT-like DNA-binding domain SLA_LP_auto_ag PF05889.8 ETN99363.1 - 2e-15 56.1 0.0 2.3e-15 55.9 0.0 1.0 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) LRR_5 PF13306.1 ETN99363.1 - 0.048 13.3 0.2 0.095 12.4 0.0 1.5 2 0 0 2 2 2 0 Leucine rich repeats (6 copies) Pkinase PF00069.20 ETN99367.1 - 8.1e-05 21.8 0.0 0.00014 21.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain 2_5_RNA_ligase2 PF13563.1 ETN99368.1 - 2.2e-05 24.2 0.1 4.4e-05 23.2 0.1 1.5 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily DUF1569 PF07606.6 ETN99368.1 - 0.08 12.8 0.1 1 9.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1569) CFEM PF05730.6 ETN99368.1 - 0.47 10.3 3.8 5.5 6.8 0.1 2.5 3 0 0 3 3 3 0 CFEM domain PBP_GOBP PF01395.17 ETN99368.1 - 0.76 9.4 6.0 0.58 9.7 0.5 2.4 2 1 1 3 3 3 0 PBP/GOBP family Tfb4 PF03850.9 ETN99369.1 - 0.0033 16.7 2.9 0.0039 16.4 2.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb4 DUF2201_N PF13203.1 ETN99369.1 - 0.0064 15.7 7.9 0.0088 15.2 5.5 1.1 1 0 0 1 1 1 1 Putative metallopeptidase domain Adaptin_binding PF10199.4 ETN99369.1 - 0.01 16.1 9.6 0.019 15.2 6.6 1.4 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 CDC45 PF02724.9 ETN99369.1 - 0.053 11.5 11.8 0.062 11.3 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.9 ETN99369.1 - 0.073 12.5 22.9 0.01 15.3 12.8 1.7 1 1 1 2 2 2 0 Pox virus Ag35 surface protein NARP1 PF12569.3 ETN99369.1 - 0.19 10.4 17.3 0.23 10.1 12.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF2730 PF10805.3 ETN99369.1 - 0.23 11.1 4.8 0.51 10.0 3.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) DUF3573 PF12097.3 ETN99369.1 - 0.45 9.0 6.7 0.57 8.7 4.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) DUF4613 PF15390.1 ETN99369.1 - 0.45 8.6 11.0 0.57 8.2 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Vfa1 PF08432.5 ETN99369.1 - 0.51 10.3 19.4 1 9.3 13.4 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Hid1 PF12722.2 ETN99369.1 - 0.57 7.8 10.9 0.64 7.6 7.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ycf1 PF05758.7 ETN99369.1 - 0.91 7.1 13.8 0.94 7.1 9.6 1.1 1 0 0 1 1 1 0 Ycf1 DUF1664 PF07889.7 ETN99369.1 - 1 9.1 7.5 2 8.2 5.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Gag_spuma PF03276.9 ETN99369.1 - 1.3 7.2 8.9 1.7 6.8 6.1 1.2 1 0 0 1 1 1 0 Spumavirus gag protein IncA PF04156.9 ETN99369.1 - 1.7 8.1 16.4 2.7 7.5 11.3 1.4 1 0 0 1 1 1 0 IncA protein N6_N4_Mtase PF01555.13 ETN99369.1 - 1.9 7.9 9.4 2.9 7.3 6.5 1.3 1 0 0 1 1 1 0 DNA methylase Neur_chan_memb PF02932.11 ETN99369.1 - 2.7 7.8 14.1 3.8 7.3 9.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LMBR1 PF04791.11 ETN99369.1 - 3.2 6.2 4.4 3.2 6.2 3.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4407 PF14362.1 ETN99369.1 - 3.8 6.3 12.3 5.8 5.7 8.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Otopetrin PF03189.8 ETN99369.1 - 4 6.3 4.8 4.9 6.0 3.3 1.2 1 0 0 1 1 1 0 Otopetrin AIF_C PF14721.1 ETN99369.1 - 4.4 7.5 9.5 1.5 9.1 4.3 1.9 1 1 1 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FHIPEP PF00771.15 ETN99369.1 - 7.3 4.7 7.2 8 4.6 5.0 1.1 1 0 0 1 1 1 0 FHIPEP family Phlebovirus_NSM PF07246.6 ETN99369.1 - 8.6 5.4 15.2 14 4.7 10.6 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M SPT2 PF08243.6 ETN99370.1 - 0.011 16.0 0.6 0.015 15.5 0.4 1.2 1 0 0 1 1 1 0 SPT2 chromatin protein PNK3P PF08645.6 ETN99370.1 - 0.012 15.0 1.8 0.014 14.8 1.2 1.1 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase Pkinase PF00069.20 ETN99372.1 - 6.1e-09 35.4 3.1 5.1e-08 32.3 0.5 2.1 2 0 0 2 2 2 2 Protein kinase domain Pyr_redox_2 PF07992.9 ETN99372.1 - 1.3e-06 28.4 0.0 2e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pkinase_Tyr PF07714.12 ETN99372.1 - 3e-06 26.5 1.1 6.8e-06 25.3 0.2 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase WD40 PF00400.27 ETN99373.1 - 5.8e-43 143.2 8.9 7.5e-11 41.4 0.2 5.1 5 1 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETN99373.1 - 1.7e-11 42.9 0.1 0.0082 14.3 0.0 4.0 2 1 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETN99373.1 - 8e-05 21.5 4.2 0.3 9.7 0.0 3.6 1 1 2 3 3 3 3 Nup133 N terminal like WD40 PF00400.27 ETN99375.1 - 1.9e-37 125.7 16.2 3e-12 45.8 0.0 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETN99375.1 - 1e-09 37.0 0.4 0.0014 16.8 0.0 3.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETN99376.1 - 1.6e-05 25.1 2.7 3.2e-05 24.1 1.9 1.5 1 0 0 1 1 1 1 TRAF-type zinc finger PMT_C PF11647.3 ETN99376.1 - 0.038 13.6 1.0 0.079 12.5 0.7 1.5 1 0 0 1 1 1 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 Filo_glycop PF01611.11 ETN99376.1 - 0.075 11.8 1.0 0.1 11.3 0.7 1.3 1 1 0 1 1 1 0 Filovirus glycoprotein UB2H PF14814.1 ETN99376.1 - 0.1 12.3 1.8 0.19 11.4 1.2 1.6 1 1 0 1 1 1 0 Bifunctional transglycosylase second domain Ly49 PF08391.5 ETN99376.1 - 0.15 12.2 15.8 0.16 12.1 3.4 2.4 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region YhdB PF14148.1 ETN99376.1 - 0.25 11.1 3.0 0.22 11.2 0.7 1.8 1 1 1 2 2 2 0 YhdB-like protein DUF3373 PF11853.3 ETN99376.1 - 0.48 8.8 9.5 0.56 8.6 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) XisI PF08869.6 ETN99376.1 - 0.55 10.3 6.8 0.86 9.7 4.7 1.3 1 0 0 1 1 1 0 XisI protein DUF3450 PF11932.3 ETN99376.1 - 0.71 9.0 10.7 0.93 8.7 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ABC_tran PF00005.22 ETN99376.1 - 0.72 10.1 5.2 1 9.6 3.6 1.3 1 0 0 1 1 1 0 ABC transporter Tmp39 PF10271.4 ETN99376.1 - 1.2 7.6 5.4 0.17 10.5 0.7 1.7 2 0 0 2 2 2 0 Putative transmembrane protein HEAT_2 PF13646.1 ETN99377.1 - 5.3e-12 45.8 0.0 0.06 13.6 0.0 5.2 3 2 2 5 5 5 4 HEAT repeats HEAT PF02985.17 ETN99377.1 - 5e-11 41.7 0.0 0.0032 17.4 0.0 6.1 8 0 0 8 8 8 2 HEAT repeat Cnd1 PF12717.2 ETN99377.1 - 2.7e-06 27.3 10.0 0.085 12.6 0.0 4.0 1 1 2 3 3 3 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 ETN99377.1 - 0.00018 21.9 0.0 41 4.8 0.0 5.9 5 2 2 7 7 7 0 HEAT-like repeat DUF3554 PF12074.3 ETN99377.1 - 0.0037 16.7 0.8 4.4 6.6 0.0 3.5 2 2 1 3 3 3 2 Domain of unknown function (DUF3554) NLE PF08154.7 ETN99377.1 - 0.013 15.4 0.9 6.1 6.9 0.0 4.5 6 0 0 6 6 6 0 NLE (NUC135) domain MMS19_C PF12460.3 ETN99377.1 - 0.41 9.3 10.9 0.45 9.1 0.3 3.4 3 2 0 3 3 3 0 RNAPII transcription regulator C-terminal DUF4485 PF14846.1 ETN99377.1 - 2.8 7.7 5.9 2.7 7.7 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4485) DUF3944 PF13099.1 ETN99377.1 - 6.2 6.3 14.4 18 4.9 0.0 5.8 7 0 0 7 7 7 0 Domain of unknown function (DUF3944) Baculo_11_kDa PF06143.6 ETN99378.1 - 1.4 8.2 6.6 2.3 7.6 0.5 2.5 3 0 0 3 3 3 0 Baculovirus 11 kDa family ATG16 PF08614.6 ETN99379.1 - 0.017 14.9 1.0 0.017 14.9 0.7 1.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Zip PF02535.17 ETN99379.1 - 0.02 13.9 1.2 0.025 13.6 0.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Prothymosin PF03247.9 ETN99382.1 - 0.28 11.3 27.6 0.41 10.8 19.1 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family BSMAP PF12280.3 ETN99382.1 - 0.47 10.3 3.8 0.5 10.2 2.6 1.0 1 0 0 1 1 1 0 Brain specific membrane anchored protein RR_TM4-6 PF06459.7 ETN99382.1 - 0.81 9.5 17.3 0.83 9.4 12.0 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Trypan_PARP PF05887.6 ETN99382.1 - 1.6 8.5 13.6 2.1 8.1 9.4 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Tim54 PF11711.3 ETN99382.1 - 1.6 7.2 11.0 1.7 7.1 7.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 POP1 PF06978.6 ETN99382.1 - 1.6 8.3 7.2 1.8 8.2 5.0 1.0 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 TRAP_alpha PF03896.11 ETN99382.1 - 5 6.0 10.0 5.6 5.8 6.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF1510 PF07423.6 ETN99382.1 - 5 6.4 25.6 5.5 6.3 17.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ycf1 PF05758.7 ETN99382.1 - 6.2 4.3 17.2 6.7 4.2 11.9 1.0 1 0 0 1 1 1 0 Ycf1 HEAT_2 PF13646.1 ETN99384.1 - 1.4e-12 47.6 0.0 0.00011 22.4 0.0 5.7 4 2 1 5 5 5 3 HEAT repeats HEAT PF02985.17 ETN99384.1 - 1.1e-07 31.2 0.0 4.9 7.4 0.0 7.5 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.1 ETN99384.1 - 0.00026 21.3 0.1 1.6 9.2 0.0 5.3 6 0 0 6 6 6 1 HEAT-like repeat DUF2435 PF10363.4 ETN99384.1 - 0.02 14.7 11.1 3.6 7.5 0.1 5.6 5 1 0 5 5 5 0 Protein of unknown function (DUF2435) Cytochrom_C PF00034.16 ETN99384.1 - 0.027 15.3 0.0 29 5.5 0.0 4.7 5 1 0 5 5 5 0 Cytochrome c DUF2459 PF09601.5 ETN99384.1 - 0.1 12.2 0.1 35 4.0 0.0 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF2459) Inhibitor_I9 PF05922.11 ETN99384.1 - 0.29 11.7 9.0 4.5 7.9 0.2 6.3 6 3 1 7 7 7 0 Peptidase inhibitor I9 DUF3944 PF13099.1 ETN99384.1 - 0.66 9.5 23.9 0.79 9.2 0.0 7.8 10 0 0 10 10 10 0 Domain of unknown function (DUF3944) RyR PF02026.11 ETN99384.1 - 0.74 9.8 5.7 4.1 7.4 0.8 3.8 3 0 0 3 3 3 0 RyR domain TPR_20 PF14561.1 ETN99384.1 - 1.7 8.8 8.1 2.9 8.0 0.0 4.8 4 1 4 8 8 8 0 Tetratricopeptide repeat FRD2 PF03197.8 ETN99384.1 - 7.9 7.0 12.1 9.6 6.8 0.2 4.2 5 0 0 5 5 3 0 Bacteriophage FRD2 protein DUF1086 PF06461.6 ETN99385.1 - 0.013 15.2 0.0 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1086) NACHT PF05729.7 ETN99385.1 - 0.015 14.9 0.1 0.25 10.9 0.0 2.7 3 0 0 3 3 3 0 NACHT domain ABC_tran PF00005.22 ETN99389.1 - 0.00046 20.4 2.3 0.0016 18.7 0.0 2.4 2 1 0 2 2 2 1 ABC transporter AAA_23 PF13476.1 ETN99389.1 - 0.0028 18.0 13.6 0.081 13.2 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 ETN99389.1 - 0.005 16.9 0.6 0.019 15.1 0.0 2.1 1 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 ETN99389.1 - 0.0053 16.2 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 ETN99389.1 - 0.0089 16.2 0.4 0.044 13.9 0.1 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 ETN99389.1 - 0.017 14.2 0.0 0.036 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 ETN99389.1 - 0.019 14.6 0.1 0.081 12.5 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 ETN99389.1 - 0.021 14.8 0.3 0.12 12.3 0.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain MCM PF00493.18 ETN99389.1 - 0.021 13.6 0.1 0.036 12.8 0.0 1.5 1 1 0 1 1 1 0 MCM2/3/5 family DUF815 PF05673.8 ETN99389.1 - 0.026 13.4 0.5 0.085 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_5 PF07728.9 ETN99389.1 - 0.027 14.1 0.0 0.056 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SE PF00437.15 ETN99389.1 - 0.037 12.9 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Y_phosphatase PF00102.22 ETN99389.1 - 0.037 13.3 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Sigma54_activ_2 PF14532.1 ETN99389.1 - 0.046 13.7 0.1 0.21 11.6 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.17 ETN99389.1 - 0.07 13.3 0.2 0.36 11.0 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Miro PF08477.8 ETN99389.1 - 0.084 13.3 1.6 0.33 11.4 0.0 2.5 2 1 1 3 3 3 0 Miro-like protein Arch_ATPase PF01637.13 ETN99389.1 - 0.086 12.5 0.1 0.086 12.5 0.0 2.7 1 1 1 2 2 2 0 Archaeal ATPase IstB_IS21 PF01695.12 ETN99389.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 ETN99389.1 - 0.48 10.7 5.9 0.76 10.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 ETN99389.1 - 1.9 9.3 4.1 3.2 8.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain T2SF PF00482.18 ETN99390.1 - 0.035 14.0 0.0 4.1 7.3 0.0 2.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F MutS_III PF05192.13 ETN99390.1 - 0.042 13.6 7.8 2.8 7.6 0.3 3.4 1 1 0 2 2 2 0 MutS domain III COG5 PF10392.4 ETN99390.1 - 0.42 10.5 9.5 0.019 14.8 1.2 2.8 3 0 0 3 3 3 0 Golgi transport complex subunit 5 DUF964 PF06133.6 ETN99390.1 - 5.3 7.1 20.0 0.36 10.8 2.6 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF964) MMR_HSR1 PF01926.18 ETN99392.1 - 2.9e-06 27.2 1.5 4.1e-05 23.5 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Spc7 PF08317.6 ETN99392.1 - 0.0019 16.9 9.3 0.0031 16.2 6.4 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_10 PF12846.2 ETN99392.1 - 0.015 14.7 0.1 3.4 7.0 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain DUF515 PF04415.7 ETN99392.1 - 0.021 13.0 3.6 0.032 12.4 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) ABC_tran PF00005.22 ETN99392.1 - 0.041 14.1 2.2 0.074 13.3 0.0 2.3 2 0 0 2 2 2 0 ABC transporter Zeta_toxin PF06414.7 ETN99392.1 - 0.64 9.0 4.3 0.34 9.9 0.3 2.5 2 2 0 2 2 2 0 Zeta toxin MT PF12777.2 ETN99394.1 - 3.6e-10 39.1 12.3 4.8e-10 38.7 8.5 1.1 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor UCH PF00443.24 ETN99394.1 - 0.056 12.5 2.9 0.057 12.5 2.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase HlyD PF00529.15 ETN99394.1 - 0.083 12.1 10.8 0.12 11.6 7.5 1.2 1 0 0 1 1 1 0 HlyD family secretion protein TraT PF05818.7 ETN99394.1 - 0.15 11.4 5.3 0.21 10.9 3.7 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Spc7 PF08317.6 ETN99394.1 - 0.31 9.6 20.2 0.39 9.3 14.0 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein GAGA_bind PF06217.7 ETN99394.1 - 0.52 10.2 5.0 0.59 10.0 3.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family PMSI1 PF15322.1 ETN99394.1 - 0.56 9.2 8.4 0.66 9.0 5.8 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Acyl-CoA_dh_C PF12806.2 ETN99394.1 - 0.98 9.2 6.0 0.79 9.5 0.2 2.5 1 1 0 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like Tropomyosin PF00261.15 ETN99394.1 - 0.99 8.4 28.3 1.7 7.6 6.5 2.3 1 1 1 2 2 2 0 Tropomyosin AAA_13 PF13166.1 ETN99394.1 - 1.2 7.4 13.0 1.8 6.8 9.0 1.2 1 0 0 1 1 1 0 AAA domain Borrelia_P83 PF05262.6 ETN99394.1 - 1.4 7.0 17.3 1.6 6.9 12.0 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Fib_alpha PF08702.5 ETN99394.1 - 1.6 8.8 10.4 0.72 9.9 5.8 1.5 2 0 0 2 2 1 0 Fibrinogen alpha/beta chain family DUF4200 PF13863.1 ETN99394.1 - 3.7 7.4 26.2 5.8 6.8 17.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Mgr1 PF08602.5 ETN99394.1 - 4 6.3 6.4 4.9 6.0 4.5 1.2 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit DUF572 PF04502.8 ETN99394.1 - 4.5 6.3 14.2 5.1 6.2 9.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) HDV_ag PF01517.13 ETN99394.1 - 5 6.7 9.1 1 8.9 3.1 1.9 1 1 1 2 2 2 0 Hepatitis delta virus delta antigen TPR_MLP1_2 PF07926.7 ETN99394.1 - 5.7 6.6 25.0 6 6.6 6.1 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein PRP1_N PF06424.7 ETN99394.1 - 5.8 7.2 10.0 8.3 6.7 7.0 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DUF1664 PF07889.7 ETN99394.1 - 6 6.6 9.2 13 5.5 0.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Leucyl-specific PF14795.1 ETN99394.1 - 9.9 6.1 8.5 15 5.5 0.6 3.6 1 1 3 4 4 4 0 Leucine-tRNA synthetase-specific domain MCR_alpha PF02249.12 ETN99395.1 - 0.19 11.7 0.1 0.54 10.2 0.0 1.7 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain DUF4307 PF14155.1 ETN99396.1 - 0.02 14.6 0.7 10 5.9 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4307) DUF2899 PF11449.3 ETN99396.1 - 0.035 13.3 0.6 0.095 11.8 0.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2899) DUF3948 PF13134.1 ETN99396.1 - 0.34 10.4 2.6 1 8.8 1.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3948) DUF4064 PF13273.1 ETN99396.1 - 0.48 10.5 5.0 0.45 10.6 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) WD40 PF00400.27 ETN99397.1 - 4e-123 397.4 32.0 1.4e-12 46.9 0.1 14.3 14 0 0 14 14 14 12 WD domain, G-beta repeat Nup160 PF11715.3 ETN99397.1 - 3.1e-18 65.2 29.6 0.087 10.9 1.0 11.2 1 1 10 11 11 11 10 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETN99397.1 - 9.1e-06 24.1 5.6 0.12 10.6 0.1 4.4 3 2 1 4 4 4 2 Cytochrome D1 heme domain DUF1652 PF07865.6 ETN99397.1 - 1.4e-05 24.5 0.1 6.9 6.3 0.0 7.0 5 2 2 8 8 8 1 Protein of unknown function (DUF1652) PD40 PF07676.7 ETN99397.1 - 8.7e-05 22.0 17.6 3.4 7.4 0.1 7.7 9 0 0 9 9 9 2 WD40-like Beta Propeller Repeat Pentapeptide PF00805.17 ETN99397.1 - 0.0002 20.5 2.2 0.017 14.3 0.8 2.5 1 1 1 2 2 2 2 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETN99397.1 - 0.0026 17.5 0.1 0.011 15.4 0.1 2.1 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Lipocalin_6 PF13944.1 ETN99397.1 - 0.016 15.3 0.9 0.081 13.0 0.1 2.6 2 0 0 2 2 2 0 Lipocalin-like domain Ubiquitin_3 PF14836.1 ETN99397.1 - 0.056 13.1 0.2 20 4.9 0.0 4.4 4 1 1 5 5 5 0 Ubiquitin-like domain DUF3732 PF12532.3 ETN99397.1 - 2.5 7.5 8.1 6 6.3 0.0 5.2 5 2 2 8 8 8 0 Protein of unknown function (DUF3732) Glycogen_syn PF05693.8 ETN99398.1 - 0.031 12.5 0.0 0.037 12.2 0.0 1.0 1 0 0 1 1 1 0 Glycogen synthase WD40 PF00400.27 ETN99403.1 - 4.2e-84 273.6 21.2 4.7e-14 51.6 0.1 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat PD40 PF07676.7 ETN99403.1 - 5.3e-11 41.9 8.5 0.79 9.4 0.0 7.8 8 0 0 8 8 8 2 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETN99403.1 - 1e-07 31.6 1.4 0.00013 21.5 0.8 3.0 1 1 2 3 3 3 2 PQQ-like domain Gmad1 PF10647.4 ETN99403.1 - 4.6e-06 26.2 0.0 0.15 11.4 0.0 4.2 2 2 3 5 5 5 2 Lipoprotein LpqB beta-propeller domain Proteasome_A_N PF10584.4 ETN99403.1 - 5.5e-06 25.5 11.1 2.8 7.3 0.3 6.7 6 0 0 6 6 6 2 Proteasome subunit A N-terminal signature DPPIV_N PF00930.16 ETN99403.1 - 9.1e-06 24.4 1.3 0.19 10.3 0.0 5.3 2 1 5 7 7 7 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF727 PF05303.7 ETN99403.1 - 1e-05 25.2 0.6 7.4 6.4 0.0 5.7 3 2 3 6 6 6 1 Protein of unknown function (DUF727) Coatomer_WDAD PF04053.9 ETN99403.1 - 0.00017 20.5 0.5 0.13 11.0 0.1 2.7 1 1 1 3 3 3 2 Coatomer WD associated region Me-amine-dh_H PF06433.6 ETN99403.1 - 0.001 17.7 0.0 0.057 12.0 0.0 2.4 2 0 0 2 2 2 1 Methylamine dehydrogenase heavy chain (MADH) DUF1258 PF06869.7 ETN99403.1 - 0.01 14.9 0.2 1.7 7.6 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1258) DUF3892 PF13031.1 ETN99403.1 - 0.013 15.9 0.5 5.4 7.4 0.0 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3892) Ricin_B_lectin PF00652.17 ETN99403.1 - 0.016 15.1 6.5 1.4 9.0 0.0 4.1 1 1 3 4 4 4 0 Ricin-type beta-trefoil lectin domain Cytochrom_D1 PF02239.11 ETN99403.1 - 0.036 12.3 0.3 9.3 4.4 0.0 3.0 1 1 2 4 4 4 0 Cytochrome D1 heme domain B_lectin PF01453.19 ETN99403.1 - 0.15 11.9 7.7 0.088 12.7 1.9 2.8 2 1 3 5 5 5 0 D-mannose binding lectin WD40 PF00400.27 ETN99404.1 - 3.3e-18 64.8 4.0 1.1e-10 40.9 0.0 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 ETN99404.1 - 1.2e-06 28.4 0.2 0.00088 19.0 0.1 3.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETN99404.1 - 0.0042 16.7 0.2 4 7.2 0.0 2.7 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETN99404.1 - 0.067 11.9 1.0 0.2 10.3 0.7 1.8 1 1 0 1 1 1 0 Nup133 N terminal like Nup160 PF11715.3 ETN99404.1 - 0.086 10.9 0.2 3.3 5.7 0.0 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 PWWP PF00855.12 ETN99405.1 - 0.48 10.6 4.9 0.12 12.5 0.6 2.1 2 0 0 2 2 2 0 PWWP domain ABC_tran PF00005.22 ETN99406.1 - 0.001 19.3 0.7 0.011 15.9 0.1 2.9 3 0 0 3 3 3 1 ABC transporter DUF815 PF05673.8 ETN99406.1 - 0.0032 16.4 0.0 0.0093 14.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF815) PduV-EutP PF10662.4 ETN99406.1 - 0.021 14.3 0.3 0.13 11.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activ_2 PF14532.1 ETN99406.1 - 0.053 13.5 0.1 0.49 10.4 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_16 PF13191.1 ETN99406.1 - 0.06 13.3 0.0 0.88 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Miro PF08477.8 ETN99406.1 - 0.17 12.3 3.7 4.4 7.8 0.1 4.1 4 0 0 4 4 4 0 Miro-like protein AAA_22 PF13401.1 ETN99406.1 - 0.21 11.6 2.8 0.61 10.2 0.0 3.2 4 0 0 4 4 4 0 AAA domain Daxx PF03344.10 ETN99407.1 - 0.0002 20.0 17.5 0.00023 19.8 12.1 1.0 1 0 0 1 1 1 1 Daxx Family DUF2457 PF10446.4 ETN99407.1 - 0.0052 15.5 24.0 0.0064 15.2 16.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Pox_Ag35 PF03286.9 ETN99407.1 - 0.015 14.8 20.6 0.025 14.1 14.3 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.9 ETN99407.1 - 0.017 13.2 18.9 0.019 13.0 13.1 1.0 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.10 ETN99407.1 - 0.02 13.5 7.8 0.019 13.6 5.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.7 ETN99407.1 - 0.025 12.5 24.1 0.028 12.3 16.7 1.0 1 0 0 1 1 1 0 Nop14-like family Spore_coat_CotO PF14153.1 ETN99407.1 - 0.031 13.7 12.5 0.037 13.4 8.7 1.2 1 0 0 1 1 1 0 Spore coat protein CotO CENP-T PF15511.1 ETN99407.1 - 0.056 12.6 12.1 0.068 12.4 8.4 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T NOA36 PF06524.7 ETN99407.1 - 0.11 11.7 17.6 0.14 11.3 12.2 1.1 1 0 0 1 1 1 0 NOA36 protein BSP_II PF05432.6 ETN99407.1 - 0.11 11.7 21.3 0.18 11.0 14.7 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF605 PF04652.11 ETN99407.1 - 0.31 10.3 13.6 0.38 10.1 9.4 1.1 1 0 0 1 1 1 0 Vta1 like DUF1510 PF07423.6 ETN99407.1 - 0.38 10.0 26.8 0.52 9.6 18.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Suf PF05843.9 ETN99407.1 - 1 8.9 8.7 1.3 8.6 6.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PPP4R2 PF09184.6 ETN99407.1 - 1.2 8.5 25.3 2 7.8 17.5 1.3 1 0 0 1 1 1 0 PPP4R2 Trypan_PARP PF05887.6 ETN99407.1 - 1.5 8.6 13.3 2.2 8.1 9.2 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Vfa1 PF08432.5 ETN99407.1 - 2 8.4 24.0 3 7.8 16.6 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Neur_chan_memb PF02932.11 ETN99407.1 - 2.3 8.0 6.0 2.7 7.8 4.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CobT PF06213.7 ETN99407.1 - 2.6 7.1 29.1 3.6 6.6 20.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop25 PF09805.4 ETN99407.1 - 2.8 8.0 26.9 4.1 7.4 18.7 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) FAM60A PF15396.1 ETN99407.1 - 3.3 7.3 9.7 4.3 7.0 6.7 1.3 1 0 0 1 1 1 0 Protein Family FAM60A DDHD PF02862.12 ETN99407.1 - 5.7 6.6 12.0 8.6 6.0 8.3 1.3 1 0 0 1 1 1 0 DDHD domain Ycf1 PF05758.7 ETN99407.1 - 6.4 4.3 15.8 7.8 4.0 11.0 1.0 1 0 0 1 1 1 0 Ycf1 DUF2151 PF10221.4 ETN99407.1 - 8.9 4.3 12.5 10 4.1 8.7 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator zf-MYND PF01753.13 ETN99408.1 - 6e-09 35.6 4.9 1.7e-08 34.2 3.4 1.8 1 1 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 ETN99408.1 - 1.3e-07 31.3 1.8 3.8e-07 29.8 1.2 1.9 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 OmpH PF03938.9 ETN99408.1 - 0.62 9.9 18.0 0.76 9.7 7.0 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Phage_Mu_Gam PF07352.7 ETN99408.1 - 0.64 9.5 4.4 3 7.3 0.6 2.1 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein PAT1 PF09770.4 ETN99408.1 - 3.6 5.7 29.2 4.7 5.3 20.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Rrn6 PF10214.4 ETN99408.1 - 5.9 4.8 17.4 8.1 4.4 12.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor IncA PF04156.9 ETN99408.1 - 7.5 6.0 22.0 4.8 6.7 0.1 2.1 2 0 0 2 2 2 0 IncA protein Pex14_N PF04695.8 ETN99408.1 - 9.4 6.2 13.3 18 5.3 9.2 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region WD40 PF00400.27 ETN99409.1 - 6.4e-112 361.9 27.6 3.4e-12 45.7 0.1 11.4 12 0 0 12 12 12 10 WD domain, G-beta repeat Nup160 PF11715.3 ETN99409.1 - 7.8e-09 34.1 16.9 1.6 6.7 0.0 8.4 1 1 7 8 8 8 5 Nucleoporin Nup120/160 DPPIV_N PF00930.16 ETN99409.1 - 1.5e-06 27.1 0.2 2.8 6.4 0.0 5.0 2 1 2 5 5 5 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.7 ETN99409.1 - 1.1e-05 24.9 2.8 5.4 6.7 0.1 5.3 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETN99409.1 - 1.3e-05 23.6 2.4 0.22 9.7 0.1 3.5 2 1 1 3 3 3 3 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETN99409.1 - 0.00017 21.1 4.0 1.4 8.3 0.0 4.7 3 2 1 4 4 4 2 PQQ-like domain Nucleoporin_N PF08801.6 ETN99409.1 - 0.0027 16.5 23.5 0.13 10.9 1.4 6.3 2 2 3 5 5 5 3 Nup133 N terminal like DUF3732 PF12532.3 ETN99409.1 - 0.0048 16.4 0.2 12 5.3 0.0 4.2 5 0 0 5 5 5 1 Protein of unknown function (DUF3732) DUF3312 PF11768.3 ETN99409.1 - 0.019 13.2 0.3 2.6 6.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3312) Imm21 PF15569.1 ETN99409.1 - 0.079 12.7 0.4 28 4.5 0.0 3.5 3 1 1 4 4 4 0 Immunity protein 21 Peptidase_C69 PF03577.10 ETN99409.1 - 1.4 7.7 3.9 20 3.8 0.0 3.8 4 1 1 5 5 5 0 Peptidase family C69 Senescence PF06911.7 ETN99410.1 - 1.1e-09 38.2 5.0 1.4e-09 37.9 3.5 1.1 1 0 0 1 1 1 1 Senescence-associated protein C1_2 PF03107.11 ETN99410.1 - 0.3 11.2 6.4 0.52 10.4 4.4 1.4 1 0 0 1 1 1 0 C1 domain OmpH PF03938.9 ETN99411.1 - 0.16 11.9 9.8 0.23 11.4 6.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) NAM-associated PF14303.1 ETN99411.1 - 0.72 10.1 11.9 1 9.6 8.2 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Vfa1 PF08432.5 ETN99411.1 - 1.1 9.2 10.6 1.4 8.8 7.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Vac_Fusion PF02346.11 ETN99411.1 - 1.8 8.0 5.2 16 5.0 0.1 3.1 3 0 0 3 3 3 0 Chordopoxvirus fusion protein zf-C3HC4_3 PF13920.1 ETN99412.1 - 6e-08 32.2 10.3 6e-08 32.2 7.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETN99412.1 - 7.1e-05 22.7 9.1 7.1e-05 22.7 6.3 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) MBT PF02820.13 ETN99412.1 - 0.00033 20.5 0.0 0.021 14.7 0.0 2.8 2 0 0 2 2 2 1 mbt repeat SAM_1 PF00536.25 ETN99412.1 - 0.0019 18.2 2.6 0.002 18.2 0.2 2.3 2 1 0 2 2 2 1 SAM domain (Sterile alpha motif) Tudor-knot PF11717.3 ETN99412.1 - 1.7 8.4 5.9 0.43 10.3 0.2 2.9 4 0 0 4 4 4 0 RNA binding activity-knot of a chromodomain HEAT_2 PF13646.1 ETN99413.1 - 2.4e-31 107.8 0.0 1.5e-08 34.8 0.0 6.0 3 2 5 8 8 8 6 HEAT repeats HEAT PF02985.17 ETN99413.1 - 1.2e-27 93.4 0.1 0.0091 16.0 0.0 9.2 9 0 0 9 9 9 6 HEAT repeat HEAT_EZ PF13513.1 ETN99413.1 - 1e-12 48.1 0.0 0.22 12.0 0.0 5.5 5 0 0 5 5 5 3 HEAT-like repeat Ank_2 PF12796.2 ETN99413.1 - 4.5e-11 42.9 0.1 4.8e-09 36.4 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Vac14_Fab1_bd PF12755.2 ETN99413.1 - 2.9e-10 40.3 9.2 0.016 15.5 0.1 6.5 4 1 4 8 8 8 4 Vacuolar 14 Fab1-binding region Ank_3 PF13606.1 ETN99413.1 - 4.6e-10 38.7 0.2 0.0017 18.4 0.0 4.5 5 0 0 5 5 4 2 Ankyrin repeat Ank PF00023.25 ETN99413.1 - 1.1e-08 34.4 0.0 2.5e-05 23.8 0.0 4.3 4 1 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 ETN99413.1 - 2e-07 31.3 0.3 8.5e-06 26.1 0.1 3.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETN99413.1 - 3.1e-07 30.4 0.1 4.3e-05 23.6 0.0 3.3 2 1 1 3 3 3 1 Ankyrin repeats (many copies) DUF2435 PF10363.4 ETN99413.1 - 2.5e-06 27.2 3.5 0.1 12.4 0.2 5.3 3 1 3 6 6 6 2 Protein of unknown function (DUF2435) Cnd1 PF12717.2 ETN99413.1 - 0.00026 20.8 21.7 0.0076 16.1 1.3 4.8 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 DUF3810 PF12725.2 ETN99413.1 - 0.00044 19.2 0.6 0.4 9.5 0.0 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF3810) UME PF08064.8 ETN99413.1 - 0.00065 19.6 7.1 0.42 10.5 0.0 4.9 4 1 2 6 6 6 3 UME (NUC010) domain MOR2-PAG1_C PF14225.1 ETN99413.1 - 0.00098 18.9 7.5 0.01 15.6 0.1 3.6 2 1 1 4 4 4 1 Cell morphogenesis C-terminal DNA_pol3_gamma3 PF12169.3 ETN99413.1 - 0.0049 16.6 0.0 1.7 8.4 0.0 3.9 2 2 3 5 5 5 1 DNA polymerase III subunits gamma and tau domain III Activator-TraM PF11657.3 ETN99413.1 - 0.38 10.2 6.8 0.21 11.0 0.1 2.9 2 1 1 3 3 3 0 Transcriptional activator TraM Syntaphilin PF15290.1 ETN99413.1 - 0.45 9.9 9.1 9.3 5.6 0.6 3.5 1 1 2 3 3 3 0 Golgi-localised syntaxin-1-binding clamp RNase_H PF00075.19 ETN99415.1 - 7.7e-17 61.8 0.0 5.2e-16 59.1 0.0 2.2 2 0 0 2 2 2 1 RNase H RVT_1 PF00078.22 ETN99415.1 - 2.4e-05 23.8 0.1 5.3e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CMAS PF02353.15 ETN99415.1 - 0.03 13.3 0.0 0.066 12.2 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase COPIIcoated_ERV PF07970.7 ETN99416.1 - 0.039 13.5 0.6 0.044 13.3 0.4 1.1 1 0 0 1 1 1 0 Endoplasmic reticulum vesicle transporter DUF3310 PF11753.3 ETN99416.1 - 0.041 13.8 1.3 4.6 7.2 0.2 2.4 2 0 0 2 2 2 0 Protein of unknwon function (DUF3310) ERAP1_C PF11838.3 ETN99417.1 - 9.8e-10 38.1 0.1 1.7e-09 37.3 0.1 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain TPR_12 PF13424.1 ETN99418.1 - 5.4e-24 83.9 3.0 4e-13 49.1 0.6 2.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETN99418.1 - 1.5e-13 49.7 12.2 5.9e-07 28.8 0.3 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETN99418.1 - 5.4e-12 44.5 1.5 7.2e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETN99418.1 - 7.7e-12 44.6 7.0 1.4e-05 24.6 0.1 2.2 1 1 1 2 2 2 2 TPR repeat TPR_10 PF13374.1 ETN99418.1 - 1.1e-10 41.1 0.0 0.00061 19.6 0.1 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETN99418.1 - 7.8e-10 37.9 7.5 0.00012 21.7 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETN99418.1 - 4.9e-09 35.3 11.3 0.00053 19.5 4.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETN99418.1 - 4.2e-05 23.4 0.7 0.016 15.3 0.3 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat SNAP PF14938.1 ETN99418.1 - 0.00013 21.2 2.0 0.00013 21.2 1.4 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_19 PF14559.1 ETN99418.1 - 0.00072 19.8 0.2 0.037 14.3 0.1 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 ETN99418.1 - 0.00073 19.6 5.7 0.0098 16.0 3.6 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 ETN99418.1 - 0.0019 18.8 0.0 0.75 10.5 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat Phage_Treg PF04761.7 ETN99418.1 - 0.0026 17.5 1.7 0.018 14.8 0.1 2.2 2 0 0 2 2 2 1 Lactococcus bacteriophage putative transcription regulator TPR_6 PF13174.1 ETN99418.1 - 0.0049 17.2 0.3 1.8 9.1 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF3568 PF12092.3 ETN99418.1 - 0.0052 16.4 0.1 0.013 15.1 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3568) DUF627 PF04781.7 ETN99418.1 - 0.0064 16.0 1.0 0.13 11.8 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF627) DUF3856 PF12968.2 ETN99418.1 - 0.018 14.8 0.1 0.028 14.2 0.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF3856) Fis1_TPR_C PF14853.1 ETN99418.1 - 0.033 14.0 2.6 0.36 10.7 0.2 2.2 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat ox_reductase_C PF08635.5 ETN99418.1 - 0.038 13.4 0.2 0.045 13.2 0.1 1.1 1 0 0 1 1 1 0 Putative oxidoreductase C terminal MIT PF04212.13 ETN99418.1 - 0.46 10.4 5.1 8.8 6.2 0.1 2.2 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Daxx PF03344.10 ETN99419.1 - 1.1 7.6 33.1 1.5 7.2 23.0 1.1 1 0 0 1 1 1 0 Daxx Family Herpes_LMP1 PF05297.6 ETN99419.1 - 3.3 6.5 8.1 4.5 6.1 5.6 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) zf-TRAF PF02176.13 ETN99420.1 - 9.1e-06 25.9 2.1 9.1e-06 25.9 1.5 2.5 2 1 0 2 2 2 1 TRAF-type zinc finger zf-H2C2_5 PF13909.1 ETN99420.1 - 0.0014 18.6 4.0 0.072 13.3 0.5 3.6 3 1 1 4 4 4 1 C2H2-type zinc-finger domain Sina PF03145.11 ETN99420.1 - 0.038 13.6 5.3 0.21 11.1 3.4 2.2 1 1 0 1 1 1 0 Seven in absentia protein family Pox_D5 PF03288.11 ETN99420.1 - 0.062 13.5 0.6 0.27 11.5 0.2 2.0 2 0 0 2 2 2 0 Poxvirus D5 protein-like DUF106 PF01956.11 ETN99420.1 - 0.14 11.7 10.1 0.19 11.2 7.0 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 Aa_trans PF01490.13 ETN99421.1 - 3.2e-20 72.0 0.3 4.2e-20 71.6 0.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4064 PF13273.1 ETN99421.1 - 2.2 8.4 7.6 3.7 7.7 2.3 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF4064) Spore_YhaL PF14147.1 ETN99421.1 - 2.7 7.4 4.6 3.1 7.3 0.8 2.7 2 0 0 2 2 2 0 Sporulation protein YhaL cNMP_binding PF00027.24 ETN99423.1 - 4.4e-10 39.2 0.0 2.4e-08 33.6 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain SR-25 PF10500.4 ETN99423.1 - 0.019 14.4 0.7 0.019 14.4 0.5 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein BOF PF04076.8 ETN99424.1 - 0.0083 15.9 0.7 0.016 15.0 0.5 1.5 1 1 0 1 1 1 1 Bacterial OB fold (BOF) protein TIP120 PF08623.5 ETN99425.1 - 0.0034 16.9 2.1 0.02 14.4 0.3 2.4 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) DUF445 PF04286.7 ETN99425.1 - 0.0056 16.2 0.0 0.008 15.7 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF445) DUF3944 PF13099.1 ETN99425.1 - 0.13 11.8 5.3 0.15 11.5 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3944) Mpp10 PF04006.7 ETN99426.1 - 0.51 8.6 20.1 0.6 8.4 13.9 1.0 1 0 0 1 1 1 0 Mpp10 protein Isy1 PF06246.7 ETN99426.1 - 0.99 8.7 7.5 1 8.6 5.2 1.0 1 0 0 1 1 1 0 Isy1-like splicing family TRAP_alpha PF03896.11 ETN99426.1 - 5 6.0 13.2 5.2 5.9 9.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4637 PF15470.1 ETN99426.1 - 5.1 6.6 7.7 5.6 6.5 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) WD40 PF00400.27 ETN99427.1 - 7.1e-31 104.9 1.4 4.4e-15 54.8 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Pentapeptide_3 PF13576.1 ETN99427.1 - 5.7e-05 22.9 1.1 5.7e-05 22.9 0.7 1.8 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) eIF2A PF08662.6 ETN99427.1 - 0.00017 21.3 0.0 0.00039 20.1 0.0 1.5 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Pentapeptide PF00805.17 ETN99427.1 - 0.00019 20.6 2.7 0.002 17.3 0.5 1.9 1 1 1 2 2 2 2 Pentapeptide repeats (8 copies) PQQ_2 PF13360.1 ETN99427.1 - 0.00036 20.0 0.0 0.00049 19.6 0.0 1.2 1 0 0 1 1 1 1 PQQ-like domain Pentapeptide_4 PF13599.1 ETN99427.1 - 0.00039 20.1 0.4 0.00064 19.4 0.3 1.4 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Nup160 PF11715.3 ETN99427.1 - 0.00075 17.7 0.1 0.047 11.8 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 ETN99427.1 - 0.032 13.3 0.1 0.85 8.6 0.0 2.0 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 ETN99427.1 - 0.039 13.6 0.3 7.7 6.3 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 ETN99427.1 - 0.069 12.4 0.8 12 5.3 0.1 2.6 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature APG12 PF04110.8 ETN99429.1 - 0.11 12.6 0.4 3.2 8.0 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 PT PF04886.7 ETN99429.1 - 0.46 9.8 21.4 0.49 9.7 3.1 3.0 2 1 0 2 2 2 0 PT repeat DUF2572 PF10833.3 ETN99430.1 - 0.0011 18.3 0.7 0.0012 18.3 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2572) LMBR1 PF04791.11 ETN99430.1 - 4.8 5.6 6.4 5.3 5.5 4.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-RanBP PF00641.13 ETN99431.1 - 6.1e-07 28.4 1.4 1.2e-06 27.5 1.0 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Paf1 PF03985.8 ETN99431.1 - 0.037 12.7 3.3 0.065 11.9 2.3 1.3 1 0 0 1 1 1 0 Paf1 HEAT PF02985.17 ETN99432.1 - 0.0032 17.4 0.0 5.1 7.4 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat DUF3944 PF13099.1 ETN99432.1 - 0.021 14.3 0.2 0.082 12.4 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3944) P16-Arc PF04699.9 ETN99432.1 - 0.11 12.4 1.0 0.23 11.4 0.4 1.6 1 1 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) DUF326 PF03860.11 ETN99432.1 - 8 6.4 8.2 30 4.6 0.2 3.6 3 0 0 3 3 3 0 Domain of Unknown Function (DUF326) Prok-RING_1 PF14446.1 ETN99433.1 - 2.5e-05 23.9 3.2 6e-05 22.6 2.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 C1_1 PF00130.17 ETN99433.1 - 0.00047 19.8 5.6 0.001 18.7 3.9 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 ETN99433.1 - 0.066 12.9 6.1 0.21 11.2 4.2 1.9 1 0 0 1 1 1 0 PHD-finger Ribosomal_L37ae PF01780.14 ETN99433.1 - 0.28 11.0 4.6 0.2 11.5 1.2 2.3 2 0 0 2 2 2 0 Ribosomal L37ae protein family zf-RING_2 PF13639.1 ETN99433.1 - 1.4 8.7 14.1 4.6 7.1 9.8 1.9 1 1 0 1 1 1 0 Ring finger domain Exonuc_VII_L PF02601.10 ETN99433.1 - 4.1 6.4 8.6 5.4 6.1 6.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit TPR_12 PF13424.1 ETN99434.1 - 3.3e-46 155.1 6.2 2.7e-18 65.6 0.2 2.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETN99434.1 - 1.3e-22 79.1 15.0 6.7e-12 44.8 1.3 2.8 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETN99434.1 - 3.4e-20 70.7 12.2 5e-09 35.3 0.4 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETN99434.1 - 6e-19 66.2 0.8 5.5e-06 25.7 0.0 3.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETN99434.1 - 7.5e-18 63.8 0.0 2.6e-06 27.1 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETN99434.1 - 1.3e-14 52.7 16.7 5.9e-07 28.8 0.4 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETN99434.1 - 7.7e-14 50.4 4.9 0.00023 20.8 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETN99434.1 - 7.4e-08 32.0 6.9 0.00044 20.2 0.1 3.9 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETN99434.1 - 0.00064 20.3 0.0 0.19 12.4 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETN99434.1 - 0.00085 19.7 0.0 1.8 9.3 0.0 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETN99434.1 - 0.0012 19.1 0.1 1.6 9.3 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF2225 PF09986.4 ETN99434.1 - 0.0019 17.6 1.2 0.003 17.0 0.8 1.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.13 ETN99434.1 - 0.0022 17.8 3.2 0.33 10.8 0.1 3.0 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 ETN99434.1 - 0.0023 18.0 0.9 0.017 15.2 0.1 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.1 ETN99434.1 - 0.0028 16.8 0.1 0.0039 16.3 0.1 1.3 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP EST1_DNA_bind PF10373.4 ETN99434.1 - 0.013 14.6 0.4 0.038 13.2 0.1 2.0 2 1 0 2 2 2 0 Est1 DNA/RNA binding domain PPR PF01535.15 ETN99434.1 - 0.033 14.1 1.5 4.5 7.4 0.0 2.9 3 0 0 3 3 3 0 PPR repeat NAGLU PF05089.7 ETN99434.1 - 0.038 12.7 0.1 0.039 12.7 0.0 1.1 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain Ten1 PF12658.2 ETN99434.1 - 0.039 13.7 0.1 1.7 8.4 0.0 2.1 1 1 1 2 2 2 0 Telomere capping, CST complex subunit DUF627 PF04781.7 ETN99434.1 - 0.052 13.1 0.2 0.51 9.9 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF627) Sel1 PF08238.7 ETN99434.1 - 0.061 13.9 0.7 2.2 9.0 0.0 2.7 2 0 0 2 2 2 0 Sel1 repeat Mob_Pre PF01076.14 ETN99434.1 - 0.064 12.8 1.4 0.082 12.5 0.4 1.6 1 1 1 2 2 2 0 Plasmid recombination enzyme TPR_19 PF14559.1 ETN99434.1 - 0.066 13.5 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_3 PF07720.7 ETN99434.1 - 0.073 12.8 2.4 0.36 10.6 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETN99434.1 - 0.1 12.4 3.2 23 4.9 0.0 3.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat NHL PF01436.16 ETN99434.1 - 0.21 11.6 1.6 0.38 10.8 0.4 2.0 2 1 1 3 3 1 0 NHL repeat DUF1743 PF08489.6 ETN99435.1 - 0.043 13.5 0.0 0.54 10.0 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1743) DUF2136 PF09907.4 ETN99436.1 - 0.019 15.0 0.1 0.032 14.3 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2136) SRP9-21 PF05486.7 ETN99436.1 - 0.043 13.5 0.7 0.059 13.1 0.5 1.2 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) NACHT PF05729.7 ETN99437.1 - 6.7e-18 64.9 0.0 1.8e-17 63.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETN99437.1 - 0.1 12.5 0.2 2 8.3 0.2 2.3 1 1 0 1 1 1 0 AAA ATPase domain TPR_1 PF00515.23 ETN99438.1 - 2.2e-11 42.8 0.6 1.2e-07 30.9 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETN99438.1 - 5.7e-11 42.2 0.0 7.8e-09 35.3 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETN99438.1 - 2.4e-10 39.4 1.7 3.1e-08 32.8 0.3 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETN99438.1 - 8.2e-09 34.7 0.2 1.5e-06 27.6 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETN99438.1 - 6.6e-08 32.0 1.0 1.3e-06 27.9 0.7 2.0 1 1 0 1 1 1 1 TPR repeat TPR_7 PF13176.1 ETN99438.1 - 9.8e-08 31.2 0.0 8.8e-06 25.1 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETN99438.1 - 1.1e-05 25.1 0.0 0.0017 18.2 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETN99438.1 - 0.00015 21.7 0.8 0.011 15.9 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 ETN99438.1 - 0.00017 21.3 0.5 0.0014 18.4 0.1 1.9 1 1 1 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 ETN99438.1 - 0.0013 19.0 0.4 0.014 15.7 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETN99438.1 - 0.0092 16.5 0.0 0.061 13.9 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETN99438.1 - 0.017 15.7 0.0 0.054 14.1 0.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Stap_Strp_toxin PF01123.15 ETN99438.1 - 0.079 13.4 1.0 0.15 12.5 0.7 1.5 1 1 0 1 1 1 0 Staphylococcal/Streptococcal toxin, OB-fold domain Apc3 PF12895.2 ETN99438.1 - 0.094 12.8 0.3 0.19 11.8 0.2 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 ETN99438.1 - 0.39 10.5 3.1 0.62 9.9 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat UCH PF00443.24 ETN99439.1 - 5e-07 29.0 1.6 1.3e-06 27.7 1.1 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SNAP-25 PF00835.14 ETN99440.1 - 0.074 13.8 0.1 0.15 12.8 0.1 1.6 1 0 0 1 1 1 0 SNAP-25 family RED_C PF07807.6 ETN99440.1 - 0.37 10.9 4.3 0.11 12.7 0.7 1.7 2 0 0 2 2 2 0 RED-like protein C-terminal region DUF1675 PF07897.6 ETN99442.1 - 1.2 8.8 12.2 2.3 8.0 8.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF4145 PF13643.1 ETN99444.1 - 0.03 14.1 0.3 0.03 14.1 0.2 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4145) Fibrinogen_C PF00147.13 ETN99444.1 - 0.042 13.4 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 Fibrinogen beta and gamma chains, C-terminal globular domain WD40 PF00400.27 ETN99445.1 - 1.4e-59 195.9 4.9 1.7e-14 53.0 0.0 5.0 5 0 0 5 5 5 5 WD domain, G-beta repeat PQQ_2 PF13360.1 ETN99445.1 - 2.7e-08 33.5 0.3 3.1e-05 23.5 0.1 2.6 1 1 1 2 2 2 2 PQQ-like domain Nup160 PF11715.3 ETN99445.1 - 3.5e-06 25.4 0.1 0.58 8.2 0.0 3.8 1 1 2 3 3 3 3 Nucleoporin Nup120/160 DUF1258 PF06869.7 ETN99445.1 - 5.8e-05 22.3 0.0 3.8 6.5 0.0 3.8 1 1 3 4 4 4 2 Protein of unknown function (DUF1258) DUF727 PF05303.7 ETN99445.1 - 8.6e-05 22.2 0.0 0.88 9.3 0.0 3.7 1 1 3 4 4 4 2 Protein of unknown function (DUF727) Nbas_N PF15492.1 ETN99445.1 - 0.00013 21.1 1.2 0.21 10.6 0.0 3.1 1 1 2 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Gmad1 PF10647.4 ETN99445.1 - 0.00056 19.3 0.1 0.027 13.8 0.0 2.7 1 1 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Proteasome_A_N PF10584.4 ETN99445.1 - 0.003 16.8 1.7 15 4.9 0.1 4.1 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature PD40 PF07676.7 ETN99445.1 - 0.0039 16.8 8.6 8.5 6.1 0.1 4.7 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat NYD-SP28_assoc PF14775.1 ETN99445.1 - 0.0042 16.7 0.0 22 4.8 0.0 3.9 4 0 0 4 4 4 0 Sperm tail C-terminal domain Cytochrom_D1 PF02239.11 ETN99445.1 - 0.0062 14.8 0.2 0.052 11.8 0.1 2.1 1 1 1 2 2 2 1 Cytochrome D1 heme domain Me-amine-dh_H PF06433.6 ETN99445.1 - 0.0068 15.0 0.0 0.98 7.9 0.0 2.5 1 1 2 3 3 3 3 Methylamine dehydrogenase heavy chain (MADH) PLD_C PF12357.3 ETN99445.1 - 0.048 13.1 0.0 7.9 6.1 0.0 3.4 3 1 1 4 4 4 0 Phospholipase D C terminal 3-dmu-9_3-mt PF06983.8 ETN99445.1 - 0.11 12.8 0.1 18 5.6 0.0 3.4 1 1 3 4 4 4 0 3-demethylubiquinone-9 3-methyltransferase NUC173 PF08161.7 ETN99447.1 - 0.0026 17.1 0.2 0.16 11.2 0.1 2.1 1 1 1 2 2 2 2 NUC173 domain DUF2052 PF09747.4 ETN99447.1 - 0.016 15.1 0.3 0.021 14.7 0.2 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) MMS22L_C PF14911.1 ETN99447.1 - 0.032 13.2 0.1 0.043 12.8 0.1 1.3 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal FbpA PF05833.6 ETN99447.1 - 0.058 11.9 1.9 0.074 11.5 1.3 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Ripply PF14998.1 ETN99449.1 - 0.027 14.5 0.0 0.064 13.3 0.0 1.6 1 0 0 1 1 1 0 Transcription Regulator Kelch_1 PF01344.20 ETN99450.1 - 1.3e-07 30.9 1.0 1.6e-06 27.5 0.2 2.7 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETN99450.1 - 5.2e-07 29.3 0.0 7.1e-06 25.7 0.0 2.7 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETN99450.1 - 2.3e-05 24.3 1.8 0.00031 20.7 0.1 3.1 4 1 1 5 5 5 1 Kelch motif Kelch_3 PF13415.1 ETN99450.1 - 0.00082 19.4 0.0 0.0046 17.0 0.0 2.2 2 1 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETN99450.1 - 0.0018 18.1 0.3 0.03 14.2 0.2 2.4 2 0 0 2 2 2 1 Kelch motif U-box PF04564.10 ETN99451.1 - 1.4e-11 44.1 0.1 3.7e-11 42.8 0.0 1.7 1 1 0 1 1 1 1 U-box domain UPRTase PF14681.1 ETN99451.1 - 0.098 11.8 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase DUF4152 PF13680.1 ETN99453.1 - 0.019 13.9 0.4 2.5 7.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4152) RasGAP PF00616.14 ETN99453.1 - 0.043 13.4 0.4 0.068 12.8 0.3 1.2 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase DUF1477 PF07346.6 ETN99453.1 - 0.056 13.4 1.4 0.59 10.1 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1477) Repressor_Mnt PF11423.3 ETN99454.1 - 0.21 10.9 1.4 17 4.8 0.0 3.2 3 0 0 3 3 3 0 Regulatory protein Mnt TPR_11 PF13414.1 ETN99455.1 - 4.3e-05 23.0 0.8 0.00023 20.7 0.3 2.2 2 0 0 2 2 2 1 TPR repeat YgaB PF14182.1 ETN99455.1 - 0.00028 21.0 6.2 0.0018 18.4 0.5 2.9 2 0 0 2 2 2 1 YgaB-like protein TPR_16 PF13432.1 ETN99455.1 - 0.009 16.6 0.2 0.026 15.2 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETN99455.1 - 0.017 15.7 0.1 1.3 9.8 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Mitofilin PF09731.4 ETN99455.1 - 0.019 13.6 9.8 0.16 10.6 4.8 2.0 2 0 0 2 2 2 0 Mitochondrial inner membrane protein BRK PF07533.11 ETN99455.1 - 0.021 14.2 0.4 0.036 13.5 0.3 1.3 1 0 0 1 1 1 0 BRK domain Atg14 PF10186.4 ETN99455.1 - 0.057 12.3 0.0 0.057 12.3 0.0 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Daxx PF03344.10 ETN99455.1 - 0.074 11.5 12.0 0.12 10.8 8.3 1.2 1 0 0 1 1 1 0 Daxx Family IncA PF04156.9 ETN99455.1 - 0.098 12.2 4.6 2.3 7.7 0.1 2.3 2 0 0 2 2 2 0 IncA protein TPR_2 PF07719.12 ETN99455.1 - 0.14 12.1 1.5 20 5.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2031 PF09592.5 ETN99455.1 - 0.21 10.6 10.2 0.54 9.3 7.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) Vfa1 PF08432.5 ETN99455.1 - 3.8 7.4 18.7 1.5 8.7 10.3 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF948 PF06103.6 ETN99455.1 - 4.6 7.1 6.6 0.98 9.3 0.1 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF3154 PF11351.3 ETN99455.1 - 5.8 6.6 6.9 7.6 6.3 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3154) HEAT_2 PF13646.1 ETN99456.1 - 2.4e-24 85.3 0.4 9.8e-08 32.1 0.0 7.1 4 2 3 7 7 7 4 HEAT repeats HEAT PF02985.17 ETN99456.1 - 4.4e-18 63.6 1.9 0.0024 17.7 0.0 9.0 9 0 0 9 9 8 3 HEAT repeat HEAT_EZ PF13513.1 ETN99456.1 - 1.9e-15 56.8 0.3 1.6e-05 25.2 0.0 7.5 7 1 1 8 8 7 3 HEAT-like repeat Ank_2 PF12796.2 ETN99456.1 - 1e-11 45.0 0.2 2.3e-09 37.4 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETN99456.1 - 1.4e-08 34.1 0.1 0.0013 18.7 0.0 3.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 ETN99456.1 - 2.5e-08 34.1 0.5 2.2e-07 31.1 0.1 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 ETN99456.1 - 3.8e-08 32.7 0.3 0.0001 21.9 0.0 3.6 3 0 0 3 3 2 2 Ankyrin repeat Vac14_Fab1_bd PF12755.2 ETN99456.1 - 3e-05 24.3 12.1 0.51 10.7 0.0 5.8 5 1 1 6 6 5 2 Vacuolar 14 Fab1-binding region DUF3554 PF12074.3 ETN99456.1 - 8.1e-05 22.1 6.8 0.0088 15.5 0.4 4.0 3 1 2 5 5 5 3 Domain of unknown function (DUF3554) Ank_5 PF13857.1 ETN99456.1 - 0.00069 19.7 0.2 0.006 16.7 0.1 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) UN_NPL4 PF11543.3 ETN99456.1 - 0.0057 16.9 0.0 0.026 14.7 0.0 2.1 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 Glycos_trans_3N PF02885.12 ETN99456.1 - 0.021 14.4 3.6 2.9 7.5 0.0 4.4 5 0 0 5 5 4 0 Glycosyl transferase family, helical bundle domain DUF3349 PF11829.3 ETN99456.1 - 0.026 14.9 1.5 46 4.5 0.0 4.9 2 1 2 4 4 4 0 Protein of unknown function (DUF3349) HEAT_PBS PF03130.11 ETN99456.1 - 0.045 14.2 0.0 1.2e+02 3.5 0.0 5.2 4 1 0 4 4 4 0 PBS lyase HEAT-like repeat UME PF08064.8 ETN99456.1 - 0.071 13.0 5.4 0.42 10.5 0.1 4.5 4 0 0 4 4 4 0 UME (NUC010) domain DnaG_DnaB_bind PF08278.6 ETN99456.1 - 0.17 12.1 10.1 0.37 11.0 0.1 5.1 6 0 0 6 6 6 0 DNA primase DnaG DnaB-binding HEAT_2 PF13646.1 ETN99457.1 - 1.4e-05 25.2 0.0 2.8e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 HEAT repeats HEAT PF02985.17 ETN99457.1 - 0.0013 18.5 0.0 0.98 9.6 0.0 2.5 2 0 0 2 2 2 2 HEAT repeat Vac14_Fab1_bd PF12755.2 ETN99457.1 - 0.0016 18.7 0.1 0.17 12.2 0.0 1.9 1 1 1 2 2 2 2 Vacuolar 14 Fab1-binding region DUF2435 PF10363.4 ETN99457.1 - 0.0039 17.0 0.1 0.16 11.9 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF2435) DUF3554 PF12074.3 ETN99457.1 - 0.0042 16.5 0.1 0.046 13.1 0.0 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF3554) HEAT_EZ PF13513.1 ETN99457.1 - 0.013 15.9 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 HEAT-like repeat TIP120 PF08623.5 ETN99457.1 - 0.028 13.9 0.2 0.057 13.0 0.1 1.6 1 1 1 2 2 2 0 TATA-binding protein interacting (TIP20) UCH_1 PF13423.1 ETN99458.1 - 0.00067 19.1 0.6 0.00067 19.1 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 ETN99458.1 - 0.025 13.6 0.7 0.028 13.5 0.5 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Folate_rec PF03024.9 ETN99458.1 - 0.11 12.0 2.5 0.13 11.8 1.8 1.1 1 0 0 1 1 1 0 Folate receptor family Zn_Tnp_IS1595 PF12760.2 ETN99458.1 - 0.68 9.7 4.6 3.1 7.6 0.2 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF678 PF05077.7 ETN99460.1 - 0.36 10.8 3.1 0.6 10.1 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF678) DUF3451 PF11933.3 ETN99460.1 - 0.47 10.2 2.4 0.6 9.8 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3451) WD40 PF00400.27 ETN99463.1 - 2.3e-54 179.4 18.7 1e-13 50.5 0.1 5.5 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_2 PF13360.1 ETN99463.1 - 0.00035 20.1 0.0 0.00099 18.6 0.0 1.8 1 1 0 1 1 1 1 PQQ-like domain NYD-SP28_assoc PF14775.1 ETN99463.1 - 0.0023 17.6 0.1 11 5.8 0.0 4.1 4 0 0 4 4 4 1 Sperm tail C-terminal domain DUF727 PF05303.7 ETN99463.1 - 0.0058 16.4 0.2 14 5.4 0.0 3.5 2 1 2 4 4 4 1 Protein of unknown function (DUF727) Cytochrom_D1 PF02239.11 ETN99463.1 - 0.0097 14.2 0.3 0.055 11.7 0.1 1.9 1 1 1 2 2 2 1 Cytochrome D1 heme domain DUF1652 PF07865.6 ETN99463.1 - 0.01 15.3 0.0 7.1 6.3 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1652) PD40 PF07676.7 ETN99463.1 - 0.05 13.2 0.5 11 5.8 0.1 3.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF3312 PF11768.3 ETN99463.1 - 0.14 10.4 0.0 10 4.2 0.0 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF3312) AAA_24 PF13479.1 ETN99466.1 - 0.0043 16.6 1.4 0.0049 16.4 0.2 1.6 2 0 0 2 2 2 1 AAA domain AbiH PF14253.1 ETN99466.1 - 0.035 13.6 0.1 0.035 13.6 0.0 2.1 2 0 0 2 2 2 0 Bacteriophage abortive infection AbiH CDC45 PF02724.9 ETN99466.1 - 3.7 5.4 9.2 4.6 5.1 6.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 ETN99466.1 - 8.8 4.9 14.5 11 4.5 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF258 PF03193.11 ETN99469.1 - 1.3e-06 27.7 0.4 3.4e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 ETN99469.1 - 7.2e-05 23.1 1.7 0.00018 21.7 0.1 2.0 2 0 0 2 2 2 1 ABC transporter G-alpha PF00503.15 ETN99469.1 - 0.00085 18.1 0.9 0.0026 16.5 0.1 1.8 1 1 1 2 2 2 1 G-protein alpha subunit AAA_29 PF13555.1 ETN99469.1 - 0.0018 17.7 0.0 0.0033 16.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 ETN99469.1 - 0.0067 15.3 0.1 0.0071 15.2 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF815 PF05673.8 ETN99469.1 - 0.026 13.4 0.2 0.057 12.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.18 ETN99469.1 - 0.031 14.2 0.9 0.058 13.3 0.1 1.9 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_25 PF13481.1 ETN99469.1 - 0.047 13.0 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 ETN99469.1 - 0.068 12.6 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 ETN99469.1 - 0.082 13.4 1.4 0.19 12.2 0.1 2.1 1 1 1 2 2 2 0 Miro-like protein AAA_16 PF13191.1 ETN99469.1 - 0.093 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 ETN99469.1 - 0.19 11.6 1.6 0.32 10.9 0.1 2.0 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 ETN99469.1 - 0.2 11.8 1.0 1.4 9.1 0.0 2.5 2 1 1 3 3 3 0 RNA helicase DUF4473 PF14747.1 ETN99470.1 - 0.062 13.5 0.2 0.19 11.9 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) YaaC PF14175.1 ETN99470.1 - 0.32 9.9 6.3 0.62 8.9 0.3 2.2 2 0 0 2 2 2 0 YaaC-like Protein CN_hydrolase PF00795.17 ETN99471.1 - 1.5e-09 37.4 0.0 1.8e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NACHT PF05729.7 ETN99475.1 - 2.5e-08 33.7 0.0 4e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 NACHT domain GP41 PF00517.12 ETN99476.1 - 6e-05 22.6 1.2 6.8e-05 22.5 0.8 1.0 1 0 0 1 1 1 1 Retroviral envelope protein EphA2_TM PF14575.1 ETN99476.1 - 1 9.7 2.9 1 9.8 0.3 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Toxin_64 PF15542.1 ETN99477.1 - 0.72 10.4 11.1 0.79 10.3 7.7 1.0 1 0 0 1 1 1 0 Putative toxin 64 DUF2265 PF10023.4 ETN99477.1 - 4.6 6.2 7.2 4.9 6.1 5.0 1.0 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) Transferase PF02458.10 ETN99477.1 - 7.8 4.8 9.9 8 4.7 6.9 1.0 1 0 0 1 1 1 0 Transferase family EF-hand_1 PF00036.27 ETN99478.1 - 6.7e-10 37.5 3.1 0.00025 20.1 0.2 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 ETN99478.1 - 4.5e-08 32.3 0.9 0.0022 17.7 0.2 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 ETN99478.1 - 3.2e-07 30.3 0.3 1.7e-06 28.0 0.1 2.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 ETN99478.1 - 1.7e-06 27.5 2.9 1.2e-05 24.8 0.6 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 ETN99478.1 - 6.1e-05 22.1 4.4 0.0082 15.4 0.1 2.9 3 0 0 3 3 3 2 EF hand APG12 PF04110.8 ETN99478.1 - 0.0029 17.7 0.6 3.5 7.8 0.0 3.7 3 0 0 3 3 3 2 Ubiquitin-like autophagy protein Apg12 WD40_alt PF14077.1 ETN99478.1 - 0.13 11.8 10.7 0.53 9.9 0.3 4.5 4 0 0 4 4 4 0 Alternative WD40 repeat motif ATG16 PF08614.6 ETN99478.1 - 2 8.1 48.0 0.5 10.1 11.1 3.8 3 2 0 3 3 3 0 Autophagy protein 16 (ATG16) ATP-synt_G PF04718.10 ETN99478.1 - 3.4 8.3 5.5 5.7 7.6 0.3 3.3 3 0 0 3 3 3 0 Mitochondrial ATP synthase g subunit LEM PF03020.10 ETN99479.1 - 3.7 7.0 6.9 2 7.9 1.3 2.9 3 0 0 3 3 3 0 LEM domain Plant_vir_prot PF01307.12 ETN99480.1 - 0.041 13.5 0.3 0.088 12.5 0.2 1.5 1 0 0 1 1 1 0 Plant viral movement protein EphA2_TM PF14575.1 ETN99480.1 - 0.047 14.0 0.5 0.64 10.4 0.2 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Peptidase_A8 PF01252.13 ETN99480.1 - 0.09 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Signal peptidase (SPase) II EF-hand_1 PF00036.27 ETN99480.1 - 0.13 11.6 0.0 0.28 10.6 0.0 1.6 1 0 0 1 1 1 0 EF hand YajC PF02699.10 ETN99480.1 - 0.22 11.2 0.2 0.22 11.2 0.1 1.7 2 0 0 2 2 2 0 Preprotein translocase subunit DUF2615 PF11027.3 ETN99480.1 - 6 6.8 5.6 2.1 8.3 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2615) GARS_N PF02844.10 ETN99481.1 - 0.12 12.8 0.0 2.1 8.8 0.0 2.0 1 1 1 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain HHH_7 PF14635.1 ETN99482.1 - 0.056 13.5 2.8 3 8.0 0.1 2.2 1 1 1 2 2 2 0 Helix-hairpin-helix motif EndoU_bacteria PF14436.1 ETN99482.1 - 0.11 12.3 0.7 0.13 12.1 0.5 1.2 1 0 0 1 1 1 0 Bacterial EndoU nuclease 3-HAO PF06052.7 ETN99483.1 - 0.052 12.9 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase WD40 PF00400.27 ETN99485.1 - 2.9e-16 58.6 3.5 1.2e-11 44.0 0.1 2.8 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETN99485.1 - 0.015 13.5 0.1 0.095 10.8 0.0 1.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 AAA_5 PF07728.9 ETN99489.1 - 0.00067 19.3 0.0 0.0043 16.7 0.0 2.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA PF00004.24 ETN99489.1 - 0.0012 19.0 0.3 0.013 15.7 0.0 2.8 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETN99489.1 - 0.011 15.9 0.0 0.12 12.4 0.0 2.8 2 1 0 2 2 2 0 AAA domain CAP_GLY PF01302.20 ETN99490.1 - 6.4e-07 28.9 0.1 9e-07 28.4 0.1 1.3 1 1 0 1 1 1 1 CAP-Gly domain HEAT PF02985.17 ETN99491.1 - 0.00045 20.0 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 HEAT repeat DUF3826 PF12875.2 ETN99491.1 - 0.0025 17.5 0.3 0.0029 17.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3826) HEAT_2 PF13646.1 ETN99491.1 - 0.011 15.9 0.0 0.059 13.6 0.0 2.0 2 1 0 2 2 2 0 HEAT repeats Activator-TraM PF11657.3 ETN99491.1 - 0.022 14.2 0.2 0.029 13.8 0.1 1.3 1 1 0 1 1 1 0 Transcriptional activator TraM NLE PF08154.7 ETN99491.1 - 0.033 14.2 0.8 5.4 7.1 0.0 2.3 2 0 0 2 2 2 0 NLE (NUC135) domain HEAT_EZ PF13513.1 ETN99491.1 - 0.07 13.6 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 HEAT-like repeat Hint PF01079.15 ETN99493.1 - 5.1e-08 32.3 0.0 7.9e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Hint module PT-HINT PF07591.6 ETN99493.1 - 3.1e-07 30.3 0.3 1.3e-06 28.2 0.2 2.1 1 1 0 1 1 1 1 Pretoxin HINT domain Asp_decarbox PF02261.11 ETN99493.1 - 0.0036 16.8 0.0 0.0057 16.2 0.0 1.3 1 0 0 1 1 1 1 Aspartate decarboxylase Zn_Tnp_IS1595 PF12760.2 ETN99493.1 - 0.0058 16.4 2.9 0.017 14.8 2.0 1.8 1 0 0 1 1 1 1 Transposase zinc-ribbon domain AXH PF08517.7 ETN99493.1 - 0.0082 16.3 0.0 0.02 15.0 0.0 1.7 1 1 1 2 2 2 1 Ataxin-1 and HBP1 module (AXH) DUF4598 PF15370.1 ETN99494.1 - 0.094 13.0 0.1 0.094 13.0 0.1 4.2 4 1 1 5 5 5 0 Domain of unknown function (DUF4598) DUF1929 PF09118.6 ETN99495.1 - 0.0095 16.0 1.3 0.015 15.3 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) DUF3926 PF13080.1 ETN99495.1 - 0.18 11.3 2.9 4.3 6.9 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3926) Ribosomal_S17 PF00366.15 ETN99496.1 - 6.3e-28 96.6 0.8 1.1e-27 95.8 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 RRM_1 PF00076.17 ETN99497.1 - 2.2e-14 52.8 0.0 4.3e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETN99497.1 - 3e-08 33.5 0.0 5.6e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETN99497.1 - 0.0032 17.2 0.0 0.0063 16.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4094 PF13334.1 ETN99497.1 - 1.4 9.3 8.9 2.7 8.4 6.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Lipoprotein_X PF03305.8 ETN99497.1 - 1.5 8.1 9.0 2.1 7.6 6.2 1.2 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein NACHT PF05729.7 ETN99498.1 - 0.00088 18.9 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 NACHT domain DDE_3 PF13358.1 ETN99499.1 - 0.0034 17.1 0.1 0.0044 16.7 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease PsiA PF06952.6 ETN99500.1 - 0.018 14.0 0.1 0.029 13.4 0.1 1.4 2 0 0 2 2 2 0 PsiA protein VWA_2 PF13519.1 ETN99501.1 - 8.3e-05 22.7 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 ETN99501.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 vWA found in TerF C terminus VWA PF00092.23 ETN99501.1 - 0.02 14.6 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain MIP-T3 PF10243.4 ETN99502.1 - 0.56 8.6 92.1 0.67 8.3 63.8 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 TPR_12 PF13424.1 ETN99505.1 - 7.7e-34 115.4 6.7 1.9e-13 50.1 0.7 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETN99505.1 - 4.9e-22 77.3 9.4 2.5e-12 46.2 3.8 2.3 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 ETN99505.1 - 2e-20 70.9 14.0 2e-05 24.1 0.4 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETN99505.1 - 1.8e-18 64.8 5.8 4.2e-06 26.1 0.1 3.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETN99505.1 - 2.4e-18 64.9 20.0 1.4e-06 27.6 3.5 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETN99505.1 - 6.8e-17 59.9 25.0 3.5e-06 26.4 0.2 4.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETN99505.1 - 1.9e-16 59.3 0.0 0.00011 22.0 0.0 4.4 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETN99505.1 - 2.3e-09 37.6 0.1 9.9e-06 26.0 0.1 2.6 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETN99505.1 - 6.1e-09 35.7 3.5 0.11 13.0 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 ETN99505.1 - 4.1e-07 30.0 11.6 0.00013 22.0 3.5 2.7 2 1 2 4 4 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 ETN99505.1 - 6.4e-07 29.0 7.1 0.045 13.9 0.4 5.0 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETN99505.1 - 2.4e-06 27.6 0.0 0.89 10.3 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETN99505.1 - 9.1e-06 25.9 2.4 0.3 11.4 0.1 3.5 2 1 2 4 4 4 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETN99505.1 - 0.0095 15.8 14.4 2.3 8.1 0.3 4.1 3 1 1 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 ETN99505.1 - 0.016 15.0 14.0 1.3 8.9 0.3 3.9 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Phage_Treg PF04761.7 ETN99505.1 - 0.022 14.5 0.3 0.022 14.5 0.2 3.5 3 1 1 4 4 4 0 Lactococcus bacteriophage putative transcription regulator SHNi-TPR PF10516.4 ETN99505.1 - 0.023 13.9 0.2 0.1 11.8 0.1 2.2 2 0 0 2 2 2 0 SHNi-TPR RPN7 PF10602.4 ETN99505.1 - 0.025 13.9 9.3 0.22 10.8 0.3 3.2 1 1 2 3 3 3 0 26S proteasome subunit RPN7 PY_rept_46 PF09689.5 ETN99505.1 - 0.039 14.2 0.8 0.57 10.5 0.2 2.5 2 0 0 2 2 2 0 Plasmodium yoelii repeat (PY_rept_46) Sel1 PF08238.7 ETN99505.1 - 0.082 13.5 9.9 6.9 7.4 0.6 3.8 3 0 0 3 3 3 0 Sel1 repeat DUF627 PF04781.7 ETN99505.1 - 0.084 12.5 5.1 0.9 9.1 0.2 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF627) PBP_GOBP PF01395.17 ETN99505.1 - 0.12 11.9 1.2 0.22 11.1 0.2 1.8 2 1 0 2 2 2 0 PBP/GOBP family DUF1955 PF09205.5 ETN99505.1 - 0.13 11.7 2.3 2.2 7.7 0.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1955) DUF2225 PF09986.4 ETN99505.1 - 0.14 11.5 7.3 0.27 10.6 4.3 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) Ank_2 PF12796.2 ETN99506.1 - 1.3e-09 38.2 0.1 0.0017 18.6 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETN99506.1 - 2.4e-06 27.5 0.0 0.026 14.7 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETN99506.1 - 9.4e-06 25.9 0.0 0.17 12.4 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETN99506.1 - 6.5e-05 22.7 0.0 5 7.6 0.1 4.2 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.25 ETN99506.1 - 0.007 16.1 0.0 9.2 6.2 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeat Sld5 PF05916.6 ETN99506.1 - 0.22 11.8 1.8 7.8 6.8 0.0 2.3 2 0 0 2 2 2 0 GINS complex protein Fib_alpha PF08702.5 ETN99508.1 - 0.11 12.5 16.8 0.34 11.0 1.5 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.7 ETN99508.1 - 0.21 11.8 2.0 0.75 10.0 0.1 2.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4561 PF15120.1 ETN99508.1 - 1.2 8.5 6.6 0.7 9.3 1.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4561) DUF2533 PF10752.4 ETN99508.1 - 2.6 8.4 7.8 3.8 7.8 1.2 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF2533) ADIP PF11559.3 ETN99508.1 - 8 6.3 20.6 1.5 8.7 6.4 3.0 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding SNF2_N PF00176.18 ETN99509.1 - 1.9e-46 158.2 0.7 1.6e-22 79.6 0.2 2.5 2 0 0 2 2 2 2 SNF2 family N-terminal domain zf-C3HC4_2 PF13923.1 ETN99509.1 - 2.6e-08 33.7 4.5 7.5e-08 32.2 3.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETN99509.1 - 4e-07 29.5 6.3 4e-07 29.5 4.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETN99509.1 - 1.2e-06 28.2 4.1 3.5e-06 26.7 2.8 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 ETN99509.1 - 4.5e-06 26.4 5.4 1.2e-05 25.0 3.8 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 ETN99509.1 - 1.4e-05 24.6 2.6 4e-05 23.1 1.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETN99509.1 - 2.4e-05 23.9 4.7 7.3e-05 22.4 3.2 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 ETN99509.1 - 7.2e-05 22.4 6.4 0.0001 21.9 3.5 2.1 2 0 0 2 2 1 1 RING-type zinc-finger Helicase_C PF00271.26 ETN99509.1 - 0.00054 19.7 0.0 0.0013 18.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain LMBR1 PF04791.11 ETN99509.1 - 0.0087 14.6 4.7 0.024 13.2 3.2 1.7 1 0 0 1 1 1 1 LMBR1-like membrane protein zf-rbx1 PF12678.2 ETN99509.1 - 0.057 13.5 3.1 0.27 11.3 2.1 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger Parvo_coat PF00740.13 ETN99510.1 - 1.2 8.0 23.4 1.4 7.8 16.2 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Asp-B-Hydro_N PF05279.6 ETN99510.1 - 3.6 7.3 8.9 4.5 7.0 6.2 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Sec8_exocyst PF04048.9 ETN99511.1 - 0.00028 20.5 1.1 0.00028 20.5 0.8 2.2 1 1 1 2 2 2 1 Sec8 exocyst complex component specific domain DUF3584 PF12128.3 ETN99511.1 - 0.0009 16.7 9.5 0.0011 16.3 6.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_13 PF13166.1 ETN99511.1 - 0.00099 17.6 9.7 0.0012 17.3 6.7 1.0 1 0 0 1 1 1 1 AAA domain Spc7 PF08317.6 ETN99511.1 - 0.0013 17.4 13.3 0.0016 17.1 9.2 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_27 PF13514.1 ETN99511.1 - 0.0037 15.0 9.9 0.0042 14.8 6.8 1.0 1 0 0 1 1 1 1 AAA domain DUF241 PF03087.9 ETN99511.1 - 0.0039 16.7 7.0 0.0045 16.4 4.8 1.0 1 0 0 1 1 1 1 Arabidopsis protein of unknown function Fmp27_WPPW PF10359.4 ETN99511.1 - 0.0057 15.1 8.6 0.0067 14.8 6.0 1.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF4200 PF13863.1 ETN99511.1 - 0.0057 16.5 20.3 0.021 14.7 11.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) SMC_Nse1 PF07574.8 ETN99511.1 - 0.019 14.6 0.2 0.019 14.6 0.1 2.0 1 1 0 2 2 2 0 Nse1 non-SMC component of SMC5-6 complex Bacillus_HBL PF05791.6 ETN99511.1 - 0.024 14.0 6.1 0.035 13.4 4.3 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) RPW8 PF05659.6 ETN99511.1 - 0.026 14.0 6.3 0.052 13.0 4.3 1.6 1 1 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Vps5 PF09325.5 ETN99511.1 - 0.029 13.6 0.3 0.029 13.6 0.2 2.1 1 1 1 2 2 2 0 Vps5 C terminal like Fib_alpha PF08702.5 ETN99511.1 - 0.044 13.9 10.5 1.9 8.5 4.2 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF2884 PF11101.3 ETN99511.1 - 0.045 13.1 6.2 0.058 12.7 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) PhoU PF01895.14 ETN99511.1 - 0.053 13.9 13.9 0.27 11.7 0.5 2.8 1 1 2 3 3 3 0 PhoU domain Spectrin PF00435.16 ETN99511.1 - 0.058 13.6 13.2 1.1 9.5 6.6 2.1 2 0 0 2 2 2 0 Spectrin repeat MreB_Mbl PF06723.8 ETN99511.1 - 0.062 11.8 1.2 0.069 11.7 0.8 1.1 1 0 0 1 1 1 0 MreB/Mbl protein Rootletin PF15035.1 ETN99511.1 - 0.062 13.2 10.8 0.072 13.0 7.5 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF3416 PF11896.3 ETN99511.1 - 0.062 13.2 6.9 0.11 12.4 4.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3416) CorA PF01544.13 ETN99511.1 - 0.079 11.9 8.7 0.1 11.6 0.1 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Laminin_II PF06009.7 ETN99511.1 - 0.098 12.4 12.4 0.079 12.7 2.0 2.1 1 1 1 2 2 2 0 Laminin Domain II Borrelia_P83 PF05262.6 ETN99511.1 - 0.11 10.7 13.4 0.13 10.5 9.3 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Syntaxin-6_N PF09177.6 ETN99511.1 - 0.12 12.7 10.2 3.2 8.2 4.2 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Nexin_C PF08628.7 ETN99511.1 - 0.13 12.3 3.2 1.3 9.1 0.0 2.0 1 1 1 2 2 2 0 Sorting nexin C terminal Baculo_PEP_C PF04513.7 ETN99511.1 - 0.13 12.1 2.4 4.2 7.1 0.1 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PilJ PF13675.1 ETN99511.1 - 0.14 12.5 1.9 0.31 11.3 1.3 1.7 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term APG6 PF04111.7 ETN99511.1 - 0.14 11.1 14.1 0.18 10.8 9.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 CRISPR_Cse1 PF09481.5 ETN99511.1 - 0.15 10.8 1.7 0.16 10.6 1.2 1.0 1 0 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) WXG100 PF06013.7 ETN99511.1 - 0.16 12.0 4.9 7.9 6.5 0.1 2.8 1 1 1 3 3 3 0 Proteins of 100 residues with WXG Seryl_tRNA_N PF02403.17 ETN99511.1 - 0.16 11.9 20.0 0.74 9.8 4.6 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Syntaxin_2 PF14523.1 ETN99511.1 - 0.19 11.8 9.7 0.11 12.5 2.3 2.1 1 1 1 2 2 2 0 Syntaxin-like protein DUF3552 PF12072.3 ETN99511.1 - 0.19 10.9 23.5 0.4 9.8 12.9 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF3552) DUF745 PF05335.8 ETN99511.1 - 0.22 11.0 8.8 0.25 10.8 3.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Lectin_N PF03954.9 ETN99511.1 - 0.22 10.9 5.2 1.5 8.2 3.7 2.1 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF342 PF03961.8 ETN99511.1 - 0.23 9.8 11.4 0.29 9.4 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Hormone_1 PF00103.15 ETN99511.1 - 0.25 10.6 5.7 1.3 8.2 1.4 2.2 1 1 1 2 2 2 0 Somatotropin hormone family MerR-DNA-bind PF09278.6 ETN99511.1 - 0.29 11.5 11.1 2.8 8.4 3.9 2.4 2 1 0 2 2 2 0 MerR, DNA binding Exonuc_VII_L PF02601.10 ETN99511.1 - 0.3 10.2 4.9 0.37 9.9 3.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CCDC144C PF14915.1 ETN99511.1 - 0.31 9.9 17.5 2.9 6.7 9.2 2.3 1 1 0 2 2 2 0 CCDC144C protein coiled-coil region CagE_TrbE_VirB PF03135.9 ETN99511.1 - 0.33 10.7 3.5 0.15 11.8 0.7 1.6 1 1 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system Sec2p PF06428.6 ETN99511.1 - 0.34 10.7 17.9 1.5 8.6 4.9 2.3 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Phage_Mu_F PF04233.9 ETN99511.1 - 0.36 11.3 3.2 0.46 11.0 1.3 1.7 1 1 1 2 2 1 0 Phage Mu protein F like protein GP41 PF00517.12 ETN99511.1 - 0.36 10.3 2.2 1.3 8.5 0.0 2.1 2 1 0 2 2 2 0 Retroviral envelope protein TPR_MLP1_2 PF07926.7 ETN99511.1 - 0.36 10.5 22.4 2.7 7.7 15.6 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.4 ETN99511.1 - 0.37 10.9 13.4 5 7.3 5.9 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ISG65-75 PF11727.3 ETN99511.1 - 0.38 9.7 11.3 0.44 9.5 7.8 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein ApoLp-III PF07464.6 ETN99511.1 - 0.41 10.6 14.1 6.6 6.7 7.0 2.2 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Nup54 PF13874.1 ETN99511.1 - 0.47 10.1 8.9 1.2 8.8 6.1 1.5 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 HAUS6_N PF14661.1 ETN99511.1 - 0.55 9.5 7.7 0.72 9.1 5.4 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Fzo_mitofusin PF04799.8 ETN99511.1 - 0.57 9.5 9.2 0.5 9.7 0.8 2.2 1 1 1 2 2 2 0 fzo-like conserved region FliD_C PF07195.7 ETN99511.1 - 0.62 9.3 7.6 3.6 6.8 2.0 2.1 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus UPF0449 PF15136.1 ETN99511.1 - 0.63 10.2 11.3 4.2 7.6 0.1 2.4 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 Prefoldin PF02996.12 ETN99511.1 - 0.76 9.4 18.7 0.88 9.2 0.1 2.8 1 1 0 2 2 2 0 Prefoldin subunit Med9 PF07544.8 ETN99511.1 - 0.82 9.4 15.7 0.21 11.3 2.9 2.3 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Syntaxin PF00804.20 ETN99511.1 - 0.97 9.6 14.3 0.67 10.1 0.2 2.7 1 1 0 2 2 1 0 Syntaxin DNA_topoisoIV PF00521.15 ETN99511.1 - 1 8.0 8.0 1.1 7.9 5.6 1.0 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A DUF972 PF06156.8 ETN99511.1 - 1.1 9.6 12.2 3.6 7.9 8.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Jnk-SapK_ap_N PF09744.4 ETN99511.1 - 1.2 9.1 19.5 5.4 6.9 10.4 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 TBPIP PF07106.8 ETN99511.1 - 1.2 8.6 15.4 5.7 6.4 10.6 1.9 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) V_ATPase_I PF01496.14 ETN99511.1 - 1.3 6.8 12.8 2 6.1 8.9 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Flu_NS2 PF00601.14 ETN99511.1 - 1.3 9.2 5.7 0.52 10.5 0.7 2.3 1 1 2 3 3 3 0 Influenza non-structural protein (NS2) MutS_III PF05192.13 ETN99511.1 - 1.5 8.5 6.1 2.5 7.8 4.2 1.4 1 1 0 1 1 1 0 MutS domain III ING PF12998.2 ETN99511.1 - 1.6 9.0 12.6 1.7 8.9 5.5 2.0 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding PEP-utilisers_N PF05524.8 ETN99511.1 - 1.6 8.5 5.5 12 5.7 3.1 2.1 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal DUF4164 PF13747.1 ETN99511.1 - 1.6 8.9 13.4 3.7 7.7 9.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Nup88 PF10168.4 ETN99511.1 - 1.7 6.3 9.1 2.3 5.9 6.3 1.3 1 1 0 1 1 1 0 Nuclear pore component E2R135 PF11570.3 ETN99511.1 - 2 8.5 13.1 3 7.9 5.5 2.1 1 1 1 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 DUF1664 PF07889.7 ETN99511.1 - 2.3 8.0 12.6 5.2 6.8 2.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.3 ETN99511.1 - 2.8 7.8 24.6 16 5.3 4.4 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding CCDC-167 PF15188.1 ETN99511.1 - 2.9 7.9 15.5 0.062 13.2 2.6 2.3 1 1 1 2 2 1 0 Coiled-coil domain-containing protein 167 GAS PF13851.1 ETN99511.1 - 2.9 7.0 19.6 7.9 5.6 13.6 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Phage_GPO PF05929.6 ETN99511.1 - 3 7.0 9.5 3.7 6.7 4.3 1.9 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Atg14 PF10186.4 ETN99511.1 - 3.6 6.4 16.9 35 3.2 11.7 1.9 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Prefoldin_2 PF01920.15 ETN99511.1 - 4.2 7.1 23.4 1.8 8.3 0.1 3.0 1 1 1 2 2 1 0 Prefoldin subunit FlaG PF03646.10 ETN99511.1 - 4.8 7.3 14.7 2.9 8.0 0.1 2.8 1 1 2 3 3 3 0 FlaG protein DUF948 PF06103.6 ETN99511.1 - 5.5 6.9 7.1 31 4.4 0.1 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2203 PF09969.4 ETN99511.1 - 5.9 7.1 10.1 8.5 6.6 4.8 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Prominin PF05478.6 ETN99511.1 - 6.8 4.0 7.7 13 3.2 5.4 1.4 1 1 0 1 1 1 0 Prominin Effector_1 PF04518.7 ETN99511.1 - 6.9 5.5 9.0 10 4.9 3.5 1.9 1 1 1 2 2 2 0 Effector from type III secretion system IncA PF04156.9 ETN99511.1 - 7 6.2 17.0 17 4.9 11.8 1.5 1 1 0 1 1 1 0 IncA protein Sipho_Gp157 PF05565.6 ETN99511.1 - 7.2 6.1 19.3 39 3.7 9.4 2.1 1 1 1 2 2 2 0 Siphovirus Gp157 Mnd1 PF03962.10 ETN99511.1 - 8.4 6.0 19.1 10 5.7 9.7 2.0 1 1 1 2 2 2 0 Mnd1 family DUF4375 PF14300.1 ETN99511.1 - 8.7 6.3 10.5 16 5.4 6.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4375) DUF4549 PF15082.1 ETN99511.1 - 9.3 5.8 12.5 0.14 11.8 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4549) Glyco_hydro_79n PF03662.9 ETN99512.1 - 0.017 13.7 0.0 0.022 13.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 79, N-terminal domain Gal_Lectin PF02140.13 ETN99512.1 - 0.049 13.9 1.1 0.099 12.9 0.2 1.9 2 0 0 2 2 2 0 Galactose binding lectin domain zf-UBR PF02207.15 ETN99512.1 - 0.19 11.4 2.5 0.45 10.2 1.7 1.6 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) MRG PF05712.8 ETN99514.1 - 0.09 11.6 0.1 0.16 10.8 0.0 1.4 1 1 0 1 1 1 0 MRG Adenylsucc_synt PF00709.16 ETN99514.1 - 0.11 11.1 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Adenylosuccinate synthetase Myosin_tail_1 PF01576.14 ETN99516.1 - 0.00036 18.4 13.1 0.00042 18.1 9.1 1.0 1 0 0 1 1 1 1 Myosin tail EzrA PF06160.7 ETN99516.1 - 0.013 13.7 14.0 0.015 13.4 9.7 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA IncA PF04156.9 ETN99516.1 - 0.023 14.2 16.5 0.064 12.8 11.4 1.8 1 1 0 1 1 1 0 IncA protein Laminin_II PF06009.7 ETN99516.1 - 0.049 13.3 0.2 0.049 13.3 0.2 2.2 1 1 1 2 2 2 0 Laminin Domain II Synaptobrevin PF00957.16 ETN99516.1 - 0.062 12.9 2.7 1.9 8.1 0.1 2.3 2 0 0 2 2 2 0 Synaptobrevin MscS_porin PF12795.2 ETN99516.1 - 0.068 12.4 5.8 0.067 12.5 0.3 2.1 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF972 PF06156.8 ETN99516.1 - 0.082 13.2 14.5 0.92 9.8 5.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF2077 PF09850.4 ETN99516.1 - 0.083 12.2 0.4 6.6 6.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) Filament PF00038.16 ETN99516.1 - 0.085 12.3 13.6 0.12 11.8 0.5 2.2 1 1 1 2 2 2 0 Intermediate filament protein bZIP_1 PF00170.16 ETN99516.1 - 0.1 12.5 0.2 0.1 12.5 0.2 3.5 1 1 2 4 4 4 0 bZIP transcription factor APG6 PF04111.7 ETN99516.1 - 0.11 11.4 16.3 0.14 11.1 11.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 SlyX PF04102.7 ETN99516.1 - 0.26 11.6 4.7 2 8.8 0.5 3.0 1 1 1 2 2 2 0 SlyX ATG16 PF08614.6 ETN99516.1 - 0.29 10.9 10.4 0.46 10.2 7.2 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF812 PF05667.6 ETN99516.1 - 0.31 9.4 11.5 0.41 9.0 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) NEAT PF05031.7 ETN99516.1 - 0.32 11.0 6.2 0.43 10.6 4.3 1.4 1 1 0 1 1 1 0 Iron Transport-associated domain Katanin_con80 PF13925.1 ETN99516.1 - 0.36 10.5 5.1 0.96 9.1 3.5 1.8 1 1 0 1 1 1 0 con80 domain of Katanin CENP-F_leu_zip PF10473.4 ETN99516.1 - 0.4 10.5 17.7 1.5 8.7 0.8 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 ETN99516.1 - 0.46 10.2 19.4 6.8 6.4 13.4 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 ETN99516.1 - 0.62 9.1 2.5 1.4 7.9 1.7 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF2935 PF11155.3 ETN99516.1 - 1.1 9.4 8.8 3.6 7.7 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) ADIP PF11559.3 ETN99516.1 - 1.1 9.1 16.6 3.4 7.5 6.2 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.14 ETN99516.1 - 1.2 6.9 8.4 1.5 6.6 5.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Snapin_Pallidin PF14712.1 ETN99516.1 - 2.2 8.6 10.7 1.2 9.5 0.8 2.3 1 1 1 2 2 2 0 Snapin/Pallidin Nup54 PF13874.1 ETN99516.1 - 2.5 7.7 8.6 1.8 8.2 2.4 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Spectrin PF00435.16 ETN99516.1 - 2.6 8.3 9.2 3.1 8.1 2.2 2.6 1 1 1 2 2 2 0 Spectrin repeat Exonuc_VII_L PF02601.10 ETN99516.1 - 3 6.9 10.9 3.9 6.5 7.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1043 PF06295.7 ETN99516.1 - 3.1 7.4 10.2 7.2 6.2 3.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) DUF4200 PF13863.1 ETN99516.1 - 3.4 7.6 17.0 1.1 9.2 1.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Gp-FAR-1 PF05823.7 ETN99516.1 - 4.3 7.2 10.2 2.2 8.2 3.4 2.1 1 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) UvrD-helicase PF00580.16 ETN99516.1 - 5.1 6.3 9.8 5.7 6.1 6.8 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain PIN_4 PF13638.1 ETN99516.1 - 5.5 7.0 6.6 1.6 8.8 0.4 2.0 1 1 1 2 2 2 0 PIN domain Tup_N PF08581.5 ETN99516.1 - 7.2 6.8 9.6 16 5.7 1.8 3.1 1 1 3 4 4 4 0 Tup N-terminal DegS PF05384.6 ETN99516.1 - 7.5 5.7 11.5 0.63 9.2 1.5 2.2 1 1 1 2 2 2 0 Sensor protein DegS DUF1664 PF07889.7 ETN99516.1 - 8.4 6.2 8.4 17 5.2 2.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.2 ETN99516.1 - 9.7 6.0 18.2 5.6 6.8 8.9 2.3 1 1 1 2 2 2 0 Tropomyosin like DUF2709 PF10915.3 ETN99518.1 - 0.051 12.5 3.2 0.054 12.4 2.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2709) WD40 PF00400.27 ETN99522.1 - 2.7e-50 166.5 12.6 6.6e-14 51.1 0.2 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETN99522.1 - 6.6e-13 47.6 1.4 2.7e-05 22.5 0.0 4.4 1 1 2 4 4 4 4 Nucleoporin Nup120/160 eIF2A PF08662.6 ETN99522.1 - 3.4e-10 39.9 0.1 0.00019 21.2 0.0 2.6 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 ETN99522.1 - 1.2e-06 28.1 0.2 3.6e-06 26.6 0.1 1.6 1 1 0 1 1 1 1 PQQ-like domain DUF1258 PF06869.7 ETN99522.1 - 8.3e-06 25.0 0.2 0.23 10.5 0.0 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF1258) RicinB_lectin_2 PF14200.1 ETN99522.1 - 9.4e-05 22.7 0.2 0.00057 20.2 0.0 2.3 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Nucleoporin_N PF08801.6 ETN99522.1 - 0.00034 19.4 7.6 1.1 7.8 0.1 4.1 1 1 2 3 3 3 3 Nup133 N terminal like PD40 PF07676.7 ETN99522.1 - 0.0079 15.8 1.1 3 7.6 0.1 2.6 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat DUF1652 PF07865.6 ETN99522.1 - 0.031 13.8 0.0 20 4.8 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1652) Proteasome_A_N PF10584.4 ETN99522.1 - 0.032 13.5 0.1 7.6 5.9 0.0 2.9 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature SGL PF08450.7 ETN99522.1 - 0.056 12.8 0.2 2 7.7 0.0 2.2 1 1 1 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region NYD-SP28_assoc PF14775.1 ETN99522.1 - 0.19 11.4 1.0 34 4.2 0.0 3.4 5 0 0 5 5 5 0 Sperm tail C-terminal domain TPR_11 PF13414.1 ETN99523.1 - 1.2e-06 28.0 8.1 4.3e-06 26.2 4.4 2.3 1 1 1 2 2 2 1 TPR repeat TPR_2 PF07719.12 ETN99523.1 - 1.4e-06 27.7 7.5 0.0029 17.3 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETN99523.1 - 8.5e-05 22.0 8.8 0.0051 16.3 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETN99523.1 - 0.00023 20.3 0.2 0.71 9.1 0.1 2.5 2 0 0 2 2 2 2 SHNi-TPR TPR_6 PF13174.1 ETN99523.1 - 0.00073 19.8 1.5 0.33 11.5 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETN99523.1 - 0.003 17.2 4.2 0.17 11.7 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETN99523.1 - 0.0041 17.0 5.4 0.96 9.4 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat VRP1 PF03538.9 ETN99523.1 - 0.03 13.3 1.8 0.079 12.0 1.2 1.6 1 1 1 2 2 2 0 Salmonella virulence plasmid 28.1kDa A protein TPR_14 PF13428.1 ETN99523.1 - 0.035 14.7 0.3 13 6.7 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETN99523.1 - 0.037 14.3 2.8 0.67 10.3 0.0 2.8 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETN99523.1 - 0.039 13.7 4.1 2.7 8.0 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 ETN99523.1 - 0.054 13.4 0.2 0.79 9.7 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3439 PF11921.3 ETN99523.1 - 0.11 12.1 4.9 0.19 11.5 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Apc3 PF12895.2 ETN99523.1 - 3.3 7.9 11.0 3.8 7.7 3.0 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 PUB PF09409.5 ETN99524.1 - 3.2e-05 23.5 2.6 0.00043 19.9 1.2 2.6 1 1 1 2 2 2 1 PUB domain AAA_24 PF13479.1 ETN99524.1 - 0.037 13.6 0.5 0.1 12.1 0.4 1.8 1 1 0 1 1 1 0 AAA domain DUF812 PF05667.6 ETN99524.1 - 0.084 11.3 0.8 0.089 11.2 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DNA_gyraseB_C PF00986.16 ETN99524.1 - 0.14 11.9 0.3 0.3 10.8 0.1 1.5 1 1 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus Reo_sigmaC PF04582.7 ETN99526.1 - 0.00021 20.5 2.7 0.00024 20.4 1.9 1.0 1 0 0 1 1 1 1 Reovirus sigma C capsid protein FliD_C PF07195.7 ETN99526.1 - 0.0074 15.6 20.8 0.0079 15.5 14.4 1.0 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus TPR_MLP1_2 PF07926.7 ETN99526.1 - 0.013 15.2 27.8 0.14 11.9 19.1 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.14 ETN99526.1 - 0.019 12.8 19.8 0.022 12.6 13.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CtIP_N PF10482.4 ETN99526.1 - 0.02 14.6 11.1 0.02 14.6 7.7 2.4 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Atg14 PF10186.4 ETN99526.1 - 0.021 13.7 21.3 0.027 13.3 14.8 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HOOK PF05622.7 ETN99526.1 - 0.028 12.2 25.3 0.032 12.0 17.5 1.1 1 0 0 1 1 1 0 HOOK protein APG6 PF04111.7 ETN99526.1 - 0.036 13.1 27.1 0.041 12.9 18.8 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4201 PF13870.1 ETN99526.1 - 0.037 13.4 29.0 0.042 13.2 20.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) IncA PF04156.9 ETN99526.1 - 0.051 13.1 25.1 0.23 11.0 17.4 1.8 1 1 0 1 1 1 0 IncA protein Vps5 PF09325.5 ETN99526.1 - 0.088 12.0 16.0 0.048 12.8 9.7 1.6 1 1 0 1 1 1 0 Vps5 C terminal like Laminin_II PF06009.7 ETN99526.1 - 0.15 11.8 17.3 0.19 11.5 11.6 1.5 1 1 0 1 1 1 0 Laminin Domain II Spc7 PF08317.6 ETN99526.1 - 0.15 10.7 28.6 0.27 9.8 19.8 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein ING PF12998.2 ETN99526.1 - 0.17 12.2 18.4 0.21 11.8 12.8 1.2 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding COG5 PF10392.4 ETN99526.1 - 0.19 11.6 13.3 0.98 9.3 0.4 2.1 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Mto2_bdg PF12808.2 ETN99526.1 - 0.23 11.6 13.8 0.21 11.6 0.8 2.9 2 1 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF3584 PF12128.3 ETN99526.1 - 0.34 8.1 25.4 0.35 8.1 17.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Shugoshin_N PF07558.6 ETN99526.1 - 0.38 10.4 0.2 0.38 10.4 0.2 4.3 3 1 1 4 4 4 0 Shugoshin N-terminal coiled-coil region DUF2968 PF11180.3 ETN99526.1 - 0.4 10.0 16.9 0.5 9.7 11.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF2421 PF10334.4 ETN99526.1 - 0.43 10.1 3.2 0.51 9.9 2.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2421) ATG16 PF08614.6 ETN99526.1 - 0.43 10.3 27.1 0.6 9.9 18.8 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Cep57_CLD_2 PF14197.1 ETN99526.1 - 0.72 9.8 24.7 13 5.8 5.4 3.6 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 ADIP PF11559.3 ETN99526.1 - 0.76 9.6 29.8 1.2 9.0 13.7 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1515 PF07439.6 ETN99526.1 - 0.78 9.5 9.1 0.19 11.5 1.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) CALCOCO1 PF07888.6 ETN99526.1 - 0.92 7.7 22.7 0.95 7.6 15.8 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF972 PF06156.8 ETN99526.1 - 1 9.7 25.3 1.5 9.2 6.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF3571 PF12095.3 ETN99526.1 - 1.4 9.2 11.5 1 9.6 6.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3571) DUF3087 PF11286.3 ETN99526.1 - 1.4 8.0 10.4 1.8 7.7 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) DUF904 PF06005.7 ETN99526.1 - 1.6 9.1 33.8 3 8.1 11.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Spectrin PF00435.16 ETN99526.1 - 1.9 8.8 22.2 6.6 7.0 12.5 2.5 1 1 1 2 2 2 0 Spectrin repeat CDC37_N PF03234.9 ETN99526.1 - 2 8.7 22.9 2.2 8.5 15.9 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding CENP-Q PF13094.1 ETN99526.1 - 2 8.3 25.7 6.5 6.7 17.8 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TMF_TATA_bd PF12325.3 ETN99526.1 - 2.4 7.8 24.6 0.76 9.5 7.0 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding TMCO5 PF14992.1 ETN99526.1 - 2.5 7.1 26.6 2.7 7.0 18.5 1.1 1 0 0 1 1 1 0 TMCO5 family UPF0242 PF06785.6 ETN99526.1 - 2.6 6.6 20.5 2.9 6.4 14.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) TBPIP PF07106.8 ETN99526.1 - 2.6 7.5 28.0 4.6 6.7 19.0 1.6 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMF_DNA_bd PF12329.3 ETN99526.1 - 2.7 7.8 33.6 1.6 8.6 9.2 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.4 ETN99526.1 - 2.7 7.8 30.3 3.3 7.5 21.0 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF869 PF05911.6 ETN99526.1 - 2.9 6.0 25.4 3.1 5.9 17.6 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Exonuc_VII_L PF02601.10 ETN99526.1 - 3.2 6.8 20.2 4.6 6.3 14.0 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit Seryl_tRNA_N PF02403.17 ETN99526.1 - 3.3 7.7 27.9 0.47 10.4 9.9 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain RVT_3 PF13456.1 ETN99526.1 - 3.8 7.3 5.8 6.6 6.5 0.6 2.1 1 1 1 2 2 2 0 Reverse transcriptase-like Fib_alpha PF08702.5 ETN99526.1 - 3.9 7.5 23.2 3.1 7.9 13.2 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Tom37_C PF11801.3 ETN99526.1 - 4.2 7.2 15.9 5.3 6.8 11.0 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain HemX PF04375.9 ETN99526.1 - 4.2 5.8 18.8 5.9 5.3 12.7 1.5 1 1 0 1 1 1 0 HemX Nup54 PF13874.1 ETN99526.1 - 4.3 7.0 18.1 2 8.0 10.5 1.7 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF2971 PF11185.3 ETN99526.1 - 4.8 7.9 9.8 7.2 7.4 6.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2971) DUF2730 PF10805.3 ETN99526.1 - 5.2 6.8 11.4 7 6.4 7.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) Tropomyosin_1 PF12718.2 ETN99526.1 - 5.5 6.8 32.8 42 3.9 22.7 1.9 1 1 0 1 1 1 0 Tropomyosin like TSKS PF15358.1 ETN99526.1 - 5.8 4.9 13.2 5.8 4.9 9.2 1.1 1 0 0 1 1 1 0 Testis-specific serine kinase substrate Syntaxin-6_N PF09177.6 ETN99526.1 - 6.2 7.3 14.1 7.6 7.0 9.4 1.5 1 1 0 1 1 1 0 Syntaxin 6, N-terminal COG2 PF06148.6 ETN99526.1 - 6.3 6.6 13.0 22 4.9 8.8 1.9 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 MT PF12777.2 ETN99526.1 - 6.5 5.4 12.7 7.2 5.2 8.8 1.2 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor Spc24 PF08286.6 ETN99526.1 - 7 6.3 29.1 8.4 6.1 9.1 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Cyclin_C PF02984.14 ETN99526.1 - 7.5 6.5 7.1 9.6 6.1 3.7 1.8 1 1 1 2 2 2 0 Cyclin, C-terminal domain DUF4140 PF13600.1 ETN99526.1 - 7.8 7.0 14.4 7.3 7.1 3.1 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) AAA_13 PF13166.1 ETN99526.1 - 8.2 4.7 25.5 12 4.1 17.7 1.4 1 1 0 1 1 1 0 AAA domain OmpH PF03938.9 ETN99526.1 - 8.2 6.3 27.9 12 5.8 19.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4200 PF13863.1 ETN99526.1 - 8.5 6.3 32.3 11 6.0 22.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Uds1 PF15456.1 ETN99526.1 - 8.6 6.3 15.8 19 5.2 10.7 1.8 1 1 0 1 1 1 0 Up-regulated During Septation DUF501 PF04417.7 ETN99526.1 - 9.3 6.1 8.7 1.1 9.0 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF501) Phage_GP20 PF06810.6 ETN99526.1 - 9.7 5.6 31.5 47 3.3 21.7 1.9 1 1 0 1 1 1 0 Phage minor structural protein GP20 Mnd1 PF03962.10 ETN99526.1 - 10 5.7 25.3 7.4 6.1 15.8 1.7 1 1 1 2 2 2 0 Mnd1 family zf-C3HC4_2 PF13923.1 ETN99527.1 - 0.0061 16.5 2.7 0.081 12.9 1.9 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1796 PF08795.5 ETN99527.1 - 0.076 12.6 0.1 0.089 12.4 0.1 1.2 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) DUF1644 PF07800.7 ETN99527.1 - 0.3 10.9 12.2 17 5.2 8.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) zf-BED PF02892.10 ETN99527.1 - 0.66 9.7 5.5 1.1 9.0 0.1 2.9 3 0 0 3 3 3 0 BED zinc finger Cys_knot PF00007.17 ETN99527.1 - 1 9.4 11.3 0.37 10.8 4.0 2.2 1 1 1 2 2 2 0 Cystine-knot domain Tet_JBP PF12851.2 ETN99527.1 - 1.7 7.8 4.8 2.7 7.2 2.9 1.7 1 1 1 2 2 2 0 Oxygenase domain of the 2OGFeDO superfamily Peptidase_C14 PF00656.17 ETN99528.1 - 0.00095 18.9 0.2 0.00098 18.8 0.1 1.1 1 0 0 1 1 1 1 Caspase domain TLD PF07534.11 ETN99529.1 - 2.4e-17 63.2 1.4 4.8e-17 62.2 1.0 1.5 1 0 0 1 1 1 1 TLD Ras PF00071.17 ETN99530.1 - 2e-21 76.0 0.5 2.2e-21 75.9 0.4 1.0 1 0 0 1 1 1 1 Ras family Galactosyl_T PF01762.16 ETN99530.1 - 0.01 15.4 0.0 0.011 15.3 0.0 1.0 1 0 0 1 1 1 0 Galactosyltransferase SNF2_N PF00176.18 ETN99530.1 - 0.09 11.5 0.0 0.09 11.5 0.0 1.1 1 0 0 1 1 1 0 SNF2 family N-terminal domain PglZ PF08665.7 ETN99531.1 - 0.052 13.2 0.9 0.066 12.8 0.6 1.3 1 1 0 1 1 1 0 PglZ domain S-antigen PF05756.6 ETN99531.1 - 0.76 9.7 9.1 1.1 9.2 2.8 2.4 2 0 0 2 2 2 0 S-antigen protein PBP1_TM PF14812.1 ETN99531.1 - 2.3 8.5 12.0 0.31 11.3 0.4 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.1 ETN99531.1 - 2.6 7.6 5.7 8.1 6.1 0.1 2.2 2 0 0 2 2 2 0 FAM176 family TLP-20 PF06088.6 ETN99531.1 - 4.8 6.8 9.8 10 5.7 2.7 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF2255 PF10012.4 ETN99532.1 - 0.11 12.4 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) TPR_11 PF13414.1 ETN99533.1 - 2.3e-34 116.8 34.4 2.5e-16 59.0 6.6 3.1 1 1 2 3 3 3 3 TPR repeat TPR_12 PF13424.1 ETN99533.1 - 1.4e-31 108.2 13.0 4.5e-16 58.5 3.4 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETN99533.1 - 9.7e-26 88.2 21.4 1.6e-09 36.9 2.4 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETN99533.1 - 8.2e-25 84.6 14.6 1.5e-08 33.9 0.7 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETN99533.1 - 7e-20 70.2 0.1 5.8e-07 29.2 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETN99533.1 - 6.5e-17 59.9 20.3 5.8e-06 25.7 0.2 4.0 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETN99533.1 - 1.3e-16 58.9 4.7 1.5e-05 24.4 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETN99533.1 - 4.9e-11 42.9 0.0 0.0088 16.7 0.0 3.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETN99533.1 - 1.3e-10 40.9 0.9 0.054 13.9 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETN99533.1 - 1.2e-09 37.9 0.0 0.026 15.1 0.0 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETN99533.1 - 8e-09 35.0 11.5 0.0042 17.1 0.7 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETN99533.1 - 5.5e-07 29.8 1.4 0.00025 21.3 0.3 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 ETN99533.1 - 1.1e-06 28.6 15.7 2.9e-05 24.1 10.7 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 ETN99533.1 - 6.6e-05 22.7 6.0 0.043 13.7 0.3 3.6 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain SNAP PF14938.1 ETN99533.1 - 8.7e-05 21.8 12.1 0.0021 17.2 2.5 2.4 2 1 1 3 3 3 2 Soluble NSF attachment protein, SNAP SHNi-TPR PF10516.4 ETN99533.1 - 0.0005 19.2 0.1 0.91 8.8 0.0 3.3 3 0 0 3 3 3 1 SHNi-TPR PPR PF01535.15 ETN99533.1 - 0.0051 16.6 1.3 5.4 7.2 0.1 3.6 3 0 0 3 3 3 1 PPR repeat TPR_3 PF07720.7 ETN99533.1 - 0.018 14.8 3.7 0.018 14.8 2.6 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF627 PF04781.7 ETN99533.1 - 0.073 12.6 8.9 0.29 10.7 0.3 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF627) Sel1 PF08238.7 ETN99533.1 - 0.089 13.4 11.1 4.2 8.1 0.5 3.7 3 0 0 3 3 3 0 Sel1 repeat YTH PF04146.10 ETN99533.1 - 0.19 11.2 0.2 0.19 11.2 0.2 2.2 2 2 0 2 2 2 0 YT521-B-like domain DUF1120 PF06551.7 ETN99533.1 - 0.2 11.9 0.5 9.4 6.5 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1120) Glucos_trans_II PF14264.1 ETN99533.1 - 0.83 8.5 5.0 1.7 7.6 3.5 1.4 1 0 0 1 1 1 0 Glucosyl transferase GtrII Foie-gras_1 PF11817.3 ETN99533.1 - 0.86 9.0 6.9 0.66 9.4 2.5 2.1 2 1 0 2 2 2 0 Foie gras liver health family 1 NYD-SP28_assoc PF14775.1 ETN99533.1 - 5.5 6.7 8.8 3.1 7.5 0.5 3.2 3 0 0 3 3 3 0 Sperm tail C-terminal domain R3H-assoc PF13902.1 ETN99535.1 - 0.0074 16.2 0.4 0.01 15.7 0.3 1.3 1 0 0 1 1 1 1 R3H-associated N-terminal domain PH_BEACH PF14844.1 ETN99536.1 - 0.075 12.8 0.1 0.2 11.5 0.1 1.7 1 0 0 1 1 1 0 PH domain associated with Beige/BEACH YTH PF04146.10 ETN99537.1 - 0.041 13.4 0.0 0.066 12.8 0.0 1.4 1 1 0 1 1 1 0 YT521-B-like domain Ribosomal_L11_N PF03946.9 ETN99537.1 - 0.72 9.3 2.6 0.54 9.7 0.5 1.7 2 0 0 2 2 2 0 Ribosomal protein L11, N-terminal domain MS_channel PF00924.13 ETN99538.1 - 4e-17 62.2 2.0 4e-17 62.2 1.4 2.0 2 0 0 2 2 2 1 Mechanosensitive ion channel DUF4181 PF13789.1 ETN99538.1 - 0.72 9.8 8.7 0.062 13.2 1.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) Peptidase_C14 PF00656.17 ETN99545.1 - 9.9e-11 41.8 0.6 1.3e-10 41.4 0.4 1.1 1 0 0 1 1 1 1 Caspase domain UCH PF00443.24 ETN99545.1 - 0.015 14.4 0.3 0.018 14.1 0.2 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Ldl_recept_a PF00057.13 ETN99546.1 - 0.002 17.9 2.1 0.0041 16.9 1.4 1.5 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Ribosomal_L14e PF01929.12 ETN99546.1 - 0.056 13.7 0.6 0.14 12.5 0.4 1.6 1 0 0 1 1 1 0 Ribosomal protein L14 NIF PF03031.13 ETN99547.1 - 3.4e-31 108.0 0.0 5.1e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 ETN99547.1 - 0.028 14.6 0.1 0.068 13.3 0.0 1.6 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase WD40 PF00400.27 ETN99550.1 - 3.3e-18 64.8 7.2 2.3e-06 27.2 0.0 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETN99550.1 - 0.00034 19.4 1.3 0.3 9.7 0.5 2.5 1 1 2 3 3 3 2 Nup133 N terminal like FmdE PF02663.9 ETN99550.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.6 1 1 1 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon DUF2365 PF10157.4 ETN99552.1 - 0.01 15.6 0.8 0.041 13.7 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2365) Mitofilin PF09731.4 ETN99552.1 - 0.31 9.6 3.4 0.34 9.4 2.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein ACDC PF14733.1 ETN99553.1 - 0.19 11.8 1.6 0.86 9.7 0.0 2.2 2 1 0 2 2 2 0 AP2-coincident C-terminal Packaging_FI PF14000.1 ETN99555.1 - 0.0024 18.0 1.0 0.0047 17.1 0.7 1.5 1 0 0 1 1 1 1 DNA packaging protein FI CDC45 PF02724.9 ETN99555.1 - 0.053 11.5 8.9 0.06 11.3 6.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Sec62 PF03839.11 ETN99555.1 - 4.9 6.4 7.0 6 6.1 4.9 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 YlqD PF11068.3 ETN99555.1 - 9.3 6.3 12.2 2.1 8.3 4.4 2.4 2 1 0 2 2 2 0 YlqD protein WD40 PF00400.27 ETN99556.1 - 6.5e-30 101.9 1.7 8.2e-11 41.3 0.1 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN99556.1 - 1.4e-05 23.4 0.0 0.063 11.4 0.0 2.9 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETN99556.1 - 0.0013 17.6 4.4 0.059 12.0 3.1 2.5 1 1 0 1 1 1 1 Nup133 N terminal like DUF3888 PF13027.1 ETN99556.1 - 0.08 12.8 0.8 0.16 11.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3888) DUF912 PF06024.7 ETN99558.1 - 0.018 15.0 0.8 0.018 15.0 0.6 5.9 6 2 0 6 6 6 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CENP-B_dimeris PF09026.5 ETN99558.1 - 0.042 14.0 3.0 4 7.7 0.7 3.3 3 0 0 3 3 3 0 Centromere protein B dimerisation domain RNase_H2_suC PF08615.6 ETN99558.1 - 0.055 13.3 1.0 14 5.4 1.5 2.6 2 1 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) SIT PF15330.1 ETN99559.1 - 0.047 13.8 1.2 0.082 13.0 0.9 1.5 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Peptidase_S49_N PF08496.5 ETN99559.1 - 1.2 8.8 8.5 2.4 7.9 5.9 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Tom37_C PF11801.3 ETN99559.1 - 1.7 8.4 11.3 0.047 13.5 2.4 2.0 2 0 0 2 2 2 0 Tom37 C-terminal domain DUF3381 PF11861.3 ETN99559.1 - 4.9 6.6 17.5 0.36 10.3 8.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Dicty_REP PF05086.7 ETN99559.1 - 8.2 4.0 18.0 11 3.6 12.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Trypsin PF00089.21 ETN99561.1 - 2.8e-14 53.2 0.0 3.5e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Trypsin MAS20 PF02064.10 ETN99561.1 - 0.036 13.9 0.1 0.091 12.6 0.0 1.7 2 0 0 2 2 2 0 MAS20 protein import receptor DUF2663 PF10864.3 ETN99561.1 - 0.036 14.2 0.3 0.036 14.2 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) PMP22_Claudin PF00822.15 ETN99561.1 - 0.06 12.9 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family PUA PF01472.15 ETN99562.1 - 8.4e-16 57.4 0.2 1.8e-15 56.4 0.1 1.6 1 0 0 1 1 1 1 PUA domain SAM_2 PF07647.12 ETN99563.1 - 2.6e-08 33.5 0.1 5.3e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETN99563.1 - 2.7e-05 24.2 0.2 6.3e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) KSR1-SAM PF13543.1 ETN99563.1 - 0.012 15.3 0.9 0.012 15.3 0.7 2.6 1 1 1 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 AAA_32 PF13654.1 ETN99563.1 - 0.019 13.6 10.2 0.024 13.3 6.5 1.5 1 1 1 2 2 2 0 AAA domain GST_C PF00043.20 ETN99563.1 - 0.096 12.6 0.5 0.37 10.7 0.1 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF1664 PF07889.7 ETN99563.1 - 0.74 9.6 10.4 0.8 9.5 3.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Adenylsucc_synt PF00709.16 ETN99563.1 - 1.2 7.6 6.2 5.2 5.6 4.3 1.8 1 1 0 1 1 1 0 Adenylosuccinate synthetase GrpE PF01025.14 ETN99563.1 - 1.6 8.2 10.5 1.3 8.5 4.8 2.2 1 1 1 2 2 2 0 GrpE Syntaxin-6_N PF09177.6 ETN99563.1 - 2.5 8.5 8.8 1.3 9.4 2.0 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal IncA PF04156.9 ETN99563.1 - 3.7 7.0 14.1 5.3 6.6 9.7 1.3 1 1 0 1 1 1 0 IncA protein L31 PF09784.4 ETN99563.1 - 5.3 7.1 5.6 2.6 8.1 1.3 2.3 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L31 DUF3347 PF11827.3 ETN99563.1 - 6.8 6.6 10.6 13 5.6 7.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3347) DUF948 PF06103.6 ETN99563.1 - 9.3 6.1 8.6 20 5.1 0.1 3.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.4 ETN99563.1 - 9.4 6.4 16.6 1 9.5 4.7 3.0 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GlcNAc_2-epim PF07221.6 ETN99564.1 - 0.079 11.9 0.0 0.092 11.7 0.0 1.1 1 0 0 1 1 1 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) DUF3996 PF13161.1 ETN99565.1 - 0.1 12.2 5.6 0.19 11.3 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3996) PAT1 PF09770.4 ETN99565.1 - 0.17 10.1 27.8 0.19 9.9 19.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 ETN99565.1 - 1.4 7.0 34.8 1.5 6.9 24.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Fcf1 PF04900.7 ETN99566.1 - 0.16 12.0 3.0 0.34 11.0 1.6 2.0 1 1 1 2 2 2 0 Fcf1 JAB PF01398.16 ETN99566.1 - 0.88 9.3 5.9 10 5.8 0.7 2.6 1 1 1 2 2 2 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Choline_sulf_C PF12411.3 ETN99567.1 - 0.006 16.3 1.8 0.023 14.5 0.4 2.1 1 1 1 2 2 2 1 Choline sulfatase enzyme C terminal M_domain PF12938.2 ETN99567.1 - 0.036 13.8 0.7 0.049 13.4 0.5 1.1 1 0 0 1 1 1 0 M domain of GW182 V-ATPase_H_N PF03224.9 ETN99568.1 - 0.0041 16.2 0.8 0.0054 15.9 0.6 1.2 1 0 0 1 1 1 1 V-ATPase subunit H CompInhib_SCIN PF11546.3 ETN99568.1 - 0.046 13.5 0.1 0.11 12.3 0.1 1.6 1 1 1 2 2 2 0 Staphylococcal complement inhibitor SCIN DUF326 PF03860.11 ETN99568.1 - 2.6 8.0 10.2 4.5 7.2 0.5 3.2 4 0 0 4 4 4 0 Domain of Unknown Function (DUF326) DUF4352 PF11611.3 ETN99569.1 - 0.024 14.7 0.4 0.03 14.4 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4352) DUF896 PF05979.7 ETN99569.1 - 0.079 12.5 0.4 0.17 11.4 0.1 1.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF896) WD40 PF00400.27 ETN99570.1 - 1e-09 37.9 0.4 1.9e-09 37.0 0.3 1.5 1 0 0 1 1 1 1 WD domain, G-beta repeat Alk_phosphatase PF00245.15 ETN99572.1 - 0.59 8.7 2.7 0.64 8.6 1.9 1.0 1 0 0 1 1 1 0 Alkaline phosphatase CUE PF02845.11 ETN99573.1 - 0.014 14.8 0.1 0.031 13.7 0.1 1.5 1 0 0 1 1 1 0 CUE domain AceK PF06315.6 ETN99573.1 - 0.026 12.8 0.1 0.035 12.3 0.0 1.1 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) MMR_HSR1 PF01926.18 ETN99574.1 - 0.065 13.1 0.1 0.17 11.8 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 ETN99574.1 - 0.67 9.7 5.1 3.1 7.5 3.4 2.1 1 1 0 1 1 1 0 Dynamin family Kelch_2 PF07646.10 ETN99575.1 - 6.8e-07 28.8 2.5 0.0021 17.7 0.1 3.4 3 1 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETN99575.1 - 3e-05 24.0 0.9 0.01 16.0 0.2 3.0 1 1 1 2 2 2 2 Kelch motif Kelch_1 PF01344.20 ETN99575.1 - 0.00059 19.3 1.7 0.01 15.3 0.3 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETN99575.1 - 0.0017 18.0 2.4 0.2 11.4 0.0 3.6 2 2 1 3 3 3 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETN99575.1 - 0.046 13.8 0.0 0.33 11.1 0.0 2.4 3 0 0 3 3 3 0 Galactose oxidase, central domain zf-TRAF PF02176.13 ETN99576.1 - 3.8e-08 33.5 3.1 7.4e-08 32.6 2.1 1.5 1 0 0 1 1 1 1 TRAF-type zinc finger DUF342 PF03961.8 ETN99576.1 - 0.0023 16.3 6.3 0.0024 16.3 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) Imm18 PF15566.1 ETN99576.1 - 0.0038 16.5 0.8 2.3 7.6 0.0 2.8 2 0 0 2 2 2 2 Immunity protein 18 SHQ1 PF04925.10 ETN99576.1 - 0.0051 16.2 0.8 0.0067 15.8 0.6 1.1 1 0 0 1 1 1 1 SHQ1 protein Val_tRNA-synt_C PF10458.4 ETN99576.1 - 0.015 15.3 1.2 0.015 15.3 0.8 2.8 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm DivIC PF04977.10 ETN99576.1 - 0.028 13.9 1.5 0.028 13.9 1.0 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF334 PF03904.8 ETN99576.1 - 0.12 11.7 12.5 0.15 11.3 8.6 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF334) Atg14 PF10186.4 ETN99576.1 - 0.16 10.8 6.7 0.24 10.3 4.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ATG16 PF08614.6 ETN99576.1 - 0.41 10.4 14.0 0.57 9.9 4.5 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.5 ETN99576.1 - 4.6 7.3 13.4 4 7.5 2.1 2.3 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family IncA PF04156.9 ETN99576.1 - 5.6 6.5 8.7 8.8 5.8 6.0 1.3 1 0 0 1 1 1 0 IncA protein DUF4615 PF15393.1 ETN99577.1 - 0.02 15.1 0.4 0.041 14.1 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4615) Na_Ca_ex PF01699.19 ETN99577.1 - 0.038 13.6 0.1 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 Sodium/calcium exchanger protein SHR3_chaperone PF08229.6 ETN99577.1 - 0.041 12.8 0.1 0.05 12.5 0.1 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 Tad PF13400.1 ETN99577.1 - 0.088 12.8 0.3 0.088 12.8 0.2 1.8 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like DUF3481 PF11980.3 ETN99577.1 - 0.089 12.6 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) MASE1 PF05231.9 ETN99577.1 - 0.094 11.7 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 MASE1 Glycophorin_A PF01102.13 ETN99577.1 - 0.13 12.0 0.2 0.13 12.0 0.1 2.3 1 1 1 2 2 2 0 Glycophorin A Rifin_STEVOR PF02009.11 ETN99577.1 - 0.37 10.3 0.0 0.37 10.3 0.0 2.1 1 1 1 2 2 2 0 Rifin/stevor family DUF3439 PF11921.3 ETN99577.1 - 7 6.4 12.3 0.082 12.6 2.9 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3439) WD40 PF00400.27 ETN99578.1 - 6.4e-29 98.7 12.4 4.4e-10 39.0 0.7 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN99578.1 - 2.5e-06 25.9 0.9 0.0041 15.3 0.1 2.8 1 1 2 3 3 3 2 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETN99578.1 - 0.011 15.1 0.5 0.025 13.8 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4221) XRN_N PF03159.13 ETN99579.1 - 2.4e-85 285.6 0.0 4.1e-85 284.9 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus HET PF06985.6 ETN99580.1 - 3.4 7.8 7.8 13 5.9 2.4 2.1 1 1 1 2 2 2 0 Heterokaryon incompatibility protein (HET) Kelch_6 PF13964.1 ETN99583.1 - 1.3e-09 37.7 0.7 2.7e-05 24.1 0.0 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETN99583.1 - 0.0062 16.0 5.9 0.71 9.4 0.0 3.2 4 0 0 4 4 4 2 Kelch motif RNA_pol_Rpb4 PF03874.11 ETN99583.1 - 0.037 14.0 0.3 0.053 13.5 0.2 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb4 AMPKBI PF04739.10 ETN99583.1 - 0.051 13.4 2.2 0.13 12.1 0.0 2.2 2 0 0 2 2 2 0 5'-AMP-activated protein kinase beta subunit, interation domain Oscp1 PF10188.4 ETN99585.1 - 0.051 13.4 0.3 0.058 13.2 0.2 1.1 1 0 0 1 1 1 0 Organic solute transport protein 1 zf-RING_2 PF13639.1 ETN99587.1 - 0.042 13.6 1.2 0.15 11.8 0.6 2.2 1 1 1 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.1 ETN99587.1 - 0.12 12.4 2.0 0.92 9.5 0.6 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PPR PF01535.15 ETN99588.1 - 7.7e-10 38.0 2.1 0.01 15.7 0.0 3.6 3 0 0 3 3 3 2 PPR repeat PPR_2 PF13041.1 ETN99588.1 - 1.8e-08 34.2 3.8 3.8e-05 23.5 0.2 3.1 1 1 2 3 3 3 3 PPR repeat family PPR_3 PF13812.1 ETN99588.1 - 1.5e-06 28.0 0.0 0.088 13.1 0.0 3.4 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 ETN99588.1 - 0.00028 20.2 0.3 0.14 11.6 0.0 3.1 3 0 0 3 3 3 1 PPR repeat DUF1900 PF08954.6 ETN99588.1 - 0.03 13.8 0.5 0.29 10.6 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1900) DUF3636 PF12331.3 ETN99588.1 - 0.047 13.2 0.2 0.097 12.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3636) Ca_hom_mod PF14798.1 ETN99589.1 - 0.02 13.8 1.1 0.022 13.7 0.8 1.1 1 0 0 1 1 1 0 Calcium homeostasis modulator AHSP PF09236.5 ETN99589.1 - 0.11 12.6 1.3 17 5.7 0.1 2.5 2 1 1 3 3 3 0 Alpha-haemoglobin stabilising protein DUF4094 PF13334.1 ETN99589.1 - 0.12 12.7 0.2 0.15 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) NACHT PF05729.7 ETN99590.1 - 3.1e-08 33.4 0.0 3.9e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETN99590.1 - 4.4e-05 23.7 0.7 0.0001 22.6 0.5 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ETN99590.1 - 0.0089 16.1 0.1 0.02 15.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETN99590.1 - 0.013 16.3 0.0 0.018 15.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 ETN99590.1 - 0.024 14.8 0.0 0.027 14.6 0.0 1.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 ETN99590.1 - 0.13 12.2 1.1 0.22 11.4 0.8 1.4 1 1 0 1 1 1 0 AAA domain Kdo PF06293.9 ETN99591.1 - 0.015 14.3 0.1 0.032 13.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CobT PF06213.7 ETN99591.1 - 4.4 6.3 22.3 11 5.0 15.5 1.7 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SAM_1 PF00536.25 ETN99593.1 - 0.00059 19.9 0.0 0.0015 18.6 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETN99593.1 - 0.01 15.6 0.1 0.02 14.7 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) CUB_2 PF02408.15 ETN99593.1 - 0.69 9.4 3.5 1.1 8.8 0.1 2.6 3 0 0 3 3 3 0 CUB-like domain SAM_1 PF00536.25 ETN99594.1 - 1.2e-06 28.6 0.2 3.6e-06 27.0 0.1 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETN99594.1 - 1.3e-05 24.9 0.5 3.8e-05 23.4 0.3 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 ETN99594.1 - 0.013 15.2 0.1 0.037 13.7 0.1 1.7 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Pkinase PF00069.20 ETN99595.1 - 1.6e-61 207.7 0.0 5.4e-61 206.0 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain cNMP_binding PF00027.24 ETN99595.1 - 8.7e-58 192.1 1.2 6.7e-20 70.7 0.0 4.4 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.12 ETN99595.1 - 3.7e-26 91.7 0.0 6.9e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETN99595.1 - 3.6e-06 26.1 0.0 1.2e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Cupin_2 PF07883.6 ETN99595.1 - 0.0081 15.6 1.3 2.5 7.6 0.0 3.0 3 0 0 3 3 3 2 Cupin domain DUF3514 PF12027.3 ETN99599.1 - 0.0038 16.4 0.4 0.0045 16.2 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3514) ARID PF01388.16 ETN99599.1 - 0.051 13.4 0.4 0.099 12.5 0.2 1.5 1 0 0 1 1 1 0 ARID/BRIGHT DNA binding domain Pox_Ag35 PF03286.9 ETN99600.1 - 0.062 12.8 5.0 0.084 12.3 3.5 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein XAP5 PF04921.9 ETN99600.1 - 0.54 9.7 10.2 0.35 10.4 6.1 1.4 1 1 0 1 1 1 0 XAP5, circadian clock regulator Prog_receptor PF02161.10 ETN99600.1 - 0.78 8.5 6.2 1 8.1 4.3 1.1 1 0 0 1 1 1 0 Progesterone receptor RXT2_N PF08595.6 ETN99600.1 - 0.99 9.2 9.8 1.6 8.5 6.8 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Hid1 PF12722.2 ETN99600.1 - 8.6 3.8 8.0 9.9 3.6 5.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein zf-TRAF PF02176.13 ETN99601.1 - 6.1e-05 23.3 0.5 6.1e-05 23.3 0.4 2.8 2 0 0 2 2 2 1 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 ETN99601.1 - 0.055 13.4 0.4 0.48 10.5 0.3 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETN99601.1 - 0.11 12.3 0.3 0.11 12.3 0.2 2.2 2 1 0 2 2 2 0 Ring finger domain zf-RING-like PF08746.6 ETN99601.1 - 0.41 10.6 3.4 2 8.4 2.3 2.3 1 1 0 1 1 1 0 RING-like domain DUF4131 PF13567.1 ETN99602.1 - 1.4 8.2 3.4 2.5 7.4 2.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Pex24p PF06398.6 ETN99602.1 - 3.7 6.2 5.7 2.4 6.8 1.8 1.7 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin DnaB PF00772.16 ETN99605.1 - 0.061 13.2 0.0 0.069 13.0 0.0 1.1 1 0 0 1 1 1 0 DnaB-like helicase N terminal domain Metallophos PF00149.23 ETN99606.1 - 0.0015 18.0 0.1 0.0019 17.6 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase WD40 PF00400.27 ETN99607.1 - 6.7e-91 295.2 22.3 3.9e-15 55.0 0.1 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat PQQ_2 PF13360.1 ETN99607.1 - 4.1e-15 55.9 4.0 3.4e-06 26.6 0.6 3.7 1 1 1 2 2 2 2 PQQ-like domain eIF2A PF08662.6 ETN99607.1 - 1e-12 48.1 0.0 4e-06 26.6 0.0 3.3 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.4 ETN99607.1 - 7.1e-10 38.7 1.7 0.00017 21.0 0.2 3.3 1 1 2 3 3 3 3 Lipoprotein LpqB beta-propeller domain PD40 PF07676.7 ETN99607.1 - 4.7e-08 32.5 10.1 3.1 7.5 0.0 6.4 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Me-amine-dh_H PF06433.6 ETN99607.1 - 5.7e-08 31.7 0.1 0.033 12.8 0.0 3.8 3 1 1 4 4 4 2 Methylamine dehydrogenase heavy chain (MADH) BBS2_Mid PF14783.1 ETN99607.1 - 6.1e-07 29.1 0.3 0.08 12.7 0.0 4.8 3 2 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region DUF1258 PF06869.7 ETN99607.1 - 2e-06 27.0 0.0 5 6.1 0.0 5.2 1 1 5 6 6 6 1 Protein of unknown function (DUF1258) Cytochrom_D1 PF02239.11 ETN99607.1 - 9e-06 24.2 3.1 0.033 12.4 0.1 3.3 1 1 1 3 3 3 3 Cytochrome D1 heme domain DUF727 PF05303.7 ETN99607.1 - 4.3e-05 23.2 0.0 8.8 6.1 0.0 5.4 1 1 5 6 6 6 0 Protein of unknown function (DUF727) Proteasome_A_N PF10584.4 ETN99607.1 - 0.00015 21.0 14.8 13 5.2 0.0 6.7 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature DPPIV_N PF00930.16 ETN99607.1 - 0.00026 19.6 0.5 3 6.3 0.0 4.8 1 1 4 5 5 5 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region NYD-SP28_assoc PF14775.1 ETN99607.1 - 0.0016 18.1 0.1 1.2e+02 2.4 0.0 5.6 7 0 0 7 7 7 0 Sperm tail C-terminal domain Ribonuclease PF00545.15 ETN99607.1 - 0.002 18.1 0.2 98 3.1 0.0 5.1 4 1 2 6 6 6 0 ribonuclease DUF3509 PF12021.3 ETN99607.1 - 0.0061 16.2 0.0 3.9 7.2 0.0 3.9 2 1 3 5 5 5 1 Protein of unknown function (DUF3509) PLD_C PF12357.3 ETN99607.1 - 0.037 13.5 0.1 24 4.5 0.0 4.8 6 1 1 7 7 7 0 Phospholipase D C terminal AHS2 PF02626.10 ETN99607.1 - 0.044 13.0 1.2 9.6 5.4 0.0 3.6 2 1 2 4 4 4 0 Allophanate hydrolase subunit 2 Phage_fiber PF03335.8 ETN99607.1 - 0.42 10.4 3.9 22 5.1 0.2 3.7 2 0 0 2 2 2 0 Phage tail fibre repeat SR-25 PF10500.4 ETN99608.1 - 0.0049 16.3 2.1 0.0049 16.3 1.5 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein 6PF2K PF01591.13 ETN99609.1 - 0.0034 16.4 2.3 0.0034 16.4 1.6 1.0 1 0 0 1 1 1 1 6-phosphofructo-2-kinase ERp29 PF07749.7 ETN99609.1 - 0.035 14.7 2.4 0.039 14.5 0.8 1.7 1 1 1 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain RBD-FIP PF09457.5 ETN99609.1 - 6.8 6.5 6.7 0.68 9.7 0.1 2.1 2 0 0 2 2 2 0 FIP domain WD40 PF00400.27 ETN99611.1 - 5.3e-39 130.7 7.2 3e-11 42.7 0.0 5.0 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 ETN99611.1 - 1.2e-07 31.6 0.8 1.2e-05 25.1 0.0 1.9 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETN99611.1 - 4.9e-06 24.9 0.4 0.0053 14.9 0.0 3.0 1 1 2 3 3 3 2 Nucleoporin Nup120/160 PD40 PF07676.7 ETN99611.1 - 2.3e-05 23.9 0.1 2.9 7.6 0.0 4.1 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.9 ETN99611.1 - 0.001 17.9 0.1 0.18 10.5 0.0 2.0 1 1 1 2 2 2 2 Coatomer WD associated region Nucleoporin_N PF08801.6 ETN99611.1 - 0.004 15.9 0.8 0.68 8.6 0.3 2.8 1 1 1 2 2 2 1 Nup133 N terminal like PQQ_2 PF13360.1 ETN99611.1 - 0.009 15.4 0.0 0.38 10.1 0.0 2.1 1 1 1 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETN99611.1 - 0.041 12.1 0.0 0.59 8.3 0.0 1.9 1 1 1 2 2 2 0 Cytochrome D1 heme domain DPPIV_N PF00930.16 ETN99611.1 - 0.055 12.0 0.0 0.31 9.5 0.0 2.0 1 1 1 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Resistin PF06954.6 ETN99611.1 - 0.092 13.0 0.7 14 6.0 0.0 2.7 1 1 1 2 2 2 0 Resistin Trichoplein PF13868.1 ETN99612.1 - 2.7e-32 111.5 139.1 5.5e-21 74.3 56.1 4.2 3 1 0 3 3 3 2 Tumour suppressor, Mitostatin Pkinase PF00069.20 ETN99613.1 - 2.2e-10 40.1 0.0 2.2e-10 40.1 0.0 2.3 2 1 0 2 2 1 1 Protein kinase domain DUF4071 PF13281.1 ETN99613.1 - 0.002 17.0 2.6 0.032 13.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4071) GAGA_bind PF06217.7 ETN99613.1 - 0.006 16.5 8.1 0.0077 16.2 5.6 1.2 1 0 0 1 1 1 1 GAGA binding protein-like family SprA-related PF12118.3 ETN99613.1 - 0.011 15.0 13.1 0.014 14.7 9.1 1.1 1 0 0 1 1 1 0 SprA-related family SR-25 PF10500.4 ETN99613.1 - 0.2 11.0 19.3 0.34 10.3 13.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2956 PF11169.3 ETN99613.1 - 0.24 11.3 11.9 0.11 12.5 4.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) AIF_C PF14721.1 ETN99613.1 - 0.26 11.5 10.2 0.16 12.2 2.1 2.3 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SID-1_RNA_chan PF13965.1 ETN99613.1 - 0.63 8.1 7.8 1 7.4 5.4 1.4 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 Apis_Csd PF11671.3 ETN99613.1 - 1.7 8.4 10.1 0.16 11.7 1.2 2.2 2 0 0 2 2 2 0 Complementary sex determiner protein LMBR1 PF04791.11 ETN99613.1 - 2 6.8 10.1 3 6.3 7.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein PBP1_TM PF14812.1 ETN99613.1 - 6.1 7.2 12.4 1.7 8.9 3.3 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ATP-synt_E PF05680.7 ETN99613.1 - 8.3 6.4 17.3 1.1 9.3 7.5 2.3 2 0 0 2 2 2 0 ATP synthase E chain PEX11 PF05648.9 ETN99613.1 - 10 5.3 7.3 30 3.7 0.0 2.2 1 1 1 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) DUF1690 PF07956.6 ETN99615.1 - 0.0018 18.2 3.8 0.0018 18.2 2.7 2.1 1 1 1 2 2 2 1 Protein of Unknown function (DUF1690) EssA PF10661.4 ETN99615.1 - 0.085 12.5 13.3 0.086 12.5 3.1 2.2 1 1 2 3 3 3 0 WXG100 protein secretion system (Wss), protein EssA DUF3069 PF11269.3 ETN99615.1 - 0.47 10.5 6.0 6.5 6.8 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3069) DUF3942 PF13078.1 ETN99616.1 - 0.0017 18.4 1.6 0.0017 18.4 1.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3942) Toxin-JAB1 PF15659.1 ETN99616.1 - 0.021 14.7 0.3 0.021 14.7 0.2 2.0 2 0 0 2 2 2 0 JAB-like toxin 1 DUF3666 PF12408.3 ETN99616.1 - 0.021 13.9 0.0 0.064 12.3 0.0 1.9 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase ANTH PF07651.11 ETN99616.1 - 0.041 12.5 0.4 0.041 12.5 0.3 1.8 2 0 0 2 2 2 0 ANTH domain MKT1_C PF12246.3 ETN99616.1 - 0.048 12.6 3.0 0.37 9.7 0.1 2.2 2 0 0 2 2 2 0 Temperature dependent protein affecting M2 dsRNA replication Ribonuc_L-PSP PF01042.16 ETN99616.1 - 0.062 13.0 1.6 4.9 6.9 0.2 2.6 2 1 0 2 2 2 0 Endoribonuclease L-PSP Glu-tRNAGln PF02686.10 ETN99616.1 - 0.46 10.3 5.6 1 9.2 0.3 2.8 2 1 1 3 3 3 0 Glu-tRNAGln amidotransferase C subunit Syntaxin-6_N PF09177.6 ETN99616.1 - 0.46 10.9 3.9 0.41 11.0 0.3 2.3 2 1 0 2 2 2 0 Syntaxin 6, N-terminal RPW8 PF05659.6 ETN99616.1 - 0.51 9.8 7.9 2.1 7.8 1.4 2.9 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 SUV3_C PF12513.3 ETN99616.1 - 0.96 8.9 2.9 1.4 8.3 0.3 2.8 2 1 1 3 3 3 0 Mitochondrial degradasome RNA helicase subunit C terminal Baculo_PEP_C PF04513.7 ETN99616.1 - 2.5 7.9 6.2 2.5 7.9 0.3 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mer2 PF09074.5 ETN99616.1 - 6.2 6.7 12.0 4.9 7.0 1.5 2.6 1 1 1 2 2 2 0 Mer2 L31 PF09784.4 ETN99616.1 - 9.9 6.2 6.6 7.6 6.6 0.5 2.6 1 1 0 2 2 2 0 Mitochondrial ribosomal protein L31 WD40 PF00400.27 ETN99617.1 - 7.3e-11 41.5 11.0 4.9e-08 32.5 0.1 4.1 4 1 0 4 4 4 2 WD domain, G-beta repeat Nup160 PF11715.3 ETN99617.1 - 0.0014 16.8 0.3 0.0015 16.7 0.2 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 eIF2A PF08662.6 ETN99617.1 - 0.024 14.3 0.6 0.06 13.0 0.1 1.8 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 ETN99617.1 - 0.064 11.9 0.3 0.091 11.4 0.1 1.3 1 1 0 1 1 1 0 Nup133 N terminal like Glyco_hydro_12 PF01670.11 ETN99617.1 - 0.072 12.8 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 12 PUB PF09409.5 ETN99618.1 - 0.00056 19.6 0.4 0.0028 17.3 0.3 1.9 1 1 0 1 1 1 1 PUB domain DUF2207 PF09972.4 ETN99619.1 - 0.017 13.7 2.1 0.025 13.1 1.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) O-antigen_lig PF13425.1 ETN99619.1 - 0.15 12.0 3.1 0.28 11.1 2.2 1.4 1 0 0 1 1 1 0 O-antigen ligase like membrane protein OppC_N PF12911.2 ETN99619.1 - 0.19 11.1 1.4 0.7 9.3 0.9 2.0 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF4234 PF14018.1 ETN99619.1 - 0.24 11.1 2.5 0.69 9.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) Tetraspannin PF00335.15 ETN99619.1 - 0.34 10.1 16.2 0.4 9.9 10.8 1.4 1 1 0 1 1 1 0 Tetraspanin family EIID-AGA PF03613.9 ETN99619.1 - 1.3 7.9 4.3 2 7.3 3.0 1.2 1 0 0 1 1 1 0 PTS system mannose/fructose/sorbose family IID component DUF1450 PF07293.6 ETN99619.1 - 2.8 7.9 9.0 8.9 6.3 0.0 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1450) PH PF00169.24 ETN99620.1 - 0.018 15.2 0.2 0.031 14.4 0.2 1.5 1 1 0 1 1 1 0 PH domain WD40 PF00400.27 ETN99622.1 - 1.3e-26 91.4 8.0 7.9e-11 41.4 1.5 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN99622.1 - 5.9e-08 31.3 0.9 0.00021 19.5 0.1 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 DUF2671 PF10877.3 ETN99622.1 - 0.043 13.6 1.5 0.15 11.9 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2671) WD40 PF00400.27 ETN99624.1 - 4.3e-16 58.0 0.4 1.6e-09 37.2 0.0 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETN99624.1 - 0.0007 17.8 0.1 0.16 10.0 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETN99624.1 - 0.0014 17.4 0.0 1 8.0 0.0 2.1 1 1 1 2 2 2 2 Nup133 N terminal like Ytp1 PF10355.4 ETN99624.1 - 0.056 12.6 0.2 0.067 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (Ytp1) Pecanex_C PF05041.10 ETN99625.1 - 0.078 12.0 0.0 0.099 11.6 0.0 1.2 1 0 0 1 1 1 0 Pecanex protein (C-terminus) WD40 PF00400.27 ETN99626.1 - 6.1e-21 73.4 9.0 3.9e-11 42.3 1.2 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETN99626.1 - 1.3e-06 26.8 2.9 4.7e-05 21.7 0.3 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF1056 PF06341.6 ETN99626.1 - 0.4 10.7 3.2 0.73 9.9 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1056) Fe_hyd_lg_C PF02906.9 ETN99627.1 - 1.9e-57 194.6 0.6 3.1e-57 194.0 0.4 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain HSA PF07529.8 ETN99627.1 - 0.017 14.8 2.7 0.9 9.3 0.1 2.9 2 0 0 2 2 2 0 HSA SPC22 PF04573.7 ETN99627.1 - 0.11 11.7 2.7 1.5 8.0 0.0 2.9 3 0 0 3 3 3 0 Signal peptidase subunit DUF4573 PF15140.1 ETN99629.1 - 0.53 9.8 5.2 1.5 8.3 1.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4573) CLU_N PF15044.1 ETN99629.1 - 5.9 7.1 23.2 1.5e+04 -13.4 16.1 5.6 1 1 0 1 1 1 0 Mitochondrial function, CLU-N-term Clathrin PF00637.15 ETN99630.1 - 0.0048 16.4 0.7 0.0048 16.4 0.5 2.7 2 2 1 3 3 3 1 Region in Clathrin and VPS CompInhib_SCIN PF11546.3 ETN99630.1 - 0.013 15.3 0.5 0.023 14.5 0.3 1.4 1 0 0 1 1 1 0 Staphylococcal complement inhibitor SCIN Hormone_1 PF00103.15 ETN99630.1 - 0.038 13.3 2.2 0.23 10.7 0.2 2.2 2 0 0 2 2 2 0 Somatotropin hormone family tRNA-synt_His PF13393.1 ETN99630.1 - 0.12 11.4 0.1 0.15 11.0 0.1 1.1 1 0 0 1 1 1 0 Histidyl-tRNA synthetase cNMP_binding PF00027.24 ETN99631.1 - 5.6e-11 42.1 0.0 2.5e-09 36.8 0.0 2.7 2 1 1 3 3 3 1 Cyclic nucleotide-binding domain Med3 PF11593.3 ETN99631.1 - 0.02 14.1 5.5 0.033 13.4 3.8 1.3 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal Rifin_STEVOR PF02009.11 ETN99631.1 - 0.053 13.1 1.9 0.061 12.9 1.3 1.1 1 0 0 1 1 1 0 Rifin/stevor family DUF515 PF04415.7 ETN99631.1 - 0.16 10.2 6.3 0.16 10.2 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Herpes_capsid PF06112.6 ETN99631.1 - 0.4 10.7 13.6 0.68 9.9 9.4 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DNA_pol_viral_N PF00242.12 ETN99631.1 - 0.67 8.9 5.5 0.79 8.6 3.8 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain SSP160 PF06933.6 ETN99631.1 - 6.6 4.5 19.7 7.5 4.4 13.0 1.5 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Poxvirus_B22R PF04395.7 ETN99632.1 - 0.012 15.0 1.4 0.014 14.9 1.0 1.2 1 0 0 1 1 1 0 Poxvirus B22R protein GCR PF02155.10 ETN99632.1 - 0.078 11.6 0.4 0.089 11.5 0.3 1.1 1 0 0 1 1 1 0 Glucocorticoid receptor DUF2722 PF10846.3 ETN99633.1 - 0.0075 15.3 1.5 0.0082 15.2 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Myc_target_1 PF15179.1 ETN99633.1 - 0.0081 15.7 0.8 0.012 15.2 0.6 1.3 1 1 0 1 1 1 1 Myc target protein 1 STN PF07660.9 ETN99633.1 - 0.057 12.9 0.1 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 Secretin and TonB N terminus short domain HeLo PF14479.1 ETN99634.1 - 0.019 14.6 1.0 2.8 7.6 0.1 2.1 2 0 0 2 2 2 0 Prion-inhibition and propagation HEAT_2 PF13646.1 ETN99635.1 - 4.1e-08 33.4 0.0 0.065 13.5 0.0 4.5 2 2 2 5 5 5 3 HEAT repeats HEAT PF02985.17 ETN99635.1 - 6e-06 25.8 0.0 0.42 10.8 0.0 4.8 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 ETN99635.1 - 0.00031 21.1 0.0 44 4.7 0.0 5.5 6 1 1 7 7 7 0 HEAT-like repeat DUF3385 PF11865.3 ETN99635.1 - 0.0088 15.9 1.7 4.4 7.2 0.1 3.7 2 1 1 3 3 3 1 Domain of unknown function (DUF3385) DUF3944 PF13099.1 ETN99635.1 - 0.012 15.1 4.5 0.19 11.2 0.2 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF3944) DNA_pol3_gamma3 PF12169.3 ETN99635.1 - 0.077 12.7 0.1 2.3 7.9 0.0 3.0 3 0 0 3 3 3 0 DNA polymerase III subunits gamma and tau domain III PMAIP1 PF15150.1 ETN99635.1 - 0.23 11.2 0.9 7.2 6.4 0.0 3.0 3 0 0 3 3 3 0 Phorbol-12-myristate-13-acetate-induced Peptidase_C14 PF00656.17 ETN99636.1 - 0.053 13.1 0.0 0.11 12.2 0.0 1.6 1 1 0 1 1 1 0 Caspase domain DUF1481 PF07356.7 ETN99636.1 - 0.09 12.2 0.1 0.13 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1481) RraB PF06877.6 ETN99636.1 - 0.11 13.1 0.0 0.16 12.5 0.0 1.2 1 0 0 1 1 1 0 Regulator of ribonuclease activity B RUN PF02759.14 ETN99637.1 - 0.14 11.9 1.3 0.17 11.6 0.9 1.4 1 1 0 1 1 1 0 RUN domain YebO PF13974.1 ETN99637.1 - 5.9 6.7 9.5 0.68 9.7 0.1 3.3 4 0 0 4 4 4 0 YebO-like protein Zip PF02535.17 ETN99638.1 - 0.064 12.2 0.6 0.069 12.1 0.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2911 PF11138.3 ETN99639.1 - 0.17 11.4 5.4 0.035 13.7 1.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2911) DUF1664 PF07889.7 ETN99639.1 - 0.66 9.7 4.7 3.2 7.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) WD40 PF00400.27 ETN99640.1 - 1e-15 56.8 4.0 3.1e-10 39.5 0.0 3.1 3 1 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETN99640.1 - 0.0012 17.0 0.2 0.46 8.5 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETN99640.1 - 0.019 13.7 0.6 0.82 8.3 0.0 2.0 1 1 1 2 2 2 0 Nup133 N terminal like DUF1900 PF08954.6 ETN99640.1 - 0.039 13.4 0.1 1.3 8.5 0.0 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF1900) Rieske_2 PF13806.1 ETN99640.1 - 0.13 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain DUF3751 PF12571.3 ETN99640.1 - 0.13 12.0 0.1 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 Phage tail-collar fibre protein Kelch_1 PF01344.20 ETN99641.1 - 0.025 14.0 0.5 0.085 12.4 0.1 2.0 2 0 0 2 2 2 0 Kelch motif GTP-bdg_N PF13167.1 ETN99642.1 - 0.041 13.9 0.8 0.055 13.6 0.5 1.3 1 1 0 1 1 1 0 GTP-binding GTPase N-terminal NinF PF05810.7 ETN99642.1 - 0.09 12.5 0.7 0.09 12.5 0.5 2.8 1 1 2 3 3 3 0 NinF protein P53_C PF11619.3 ETN99642.1 - 0.095 12.4 0.6 0.16 11.7 0.1 1.6 2 0 0 2 2 2 0 Transcription factor P53 - C terminal domain zf-C3HC4_4 PF15227.1 ETN99642.1 - 0.19 11.6 0.6 0.19 11.6 0.4 2.8 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 ETN99642.1 - 0.29 11.1 8.2 0.089 12.8 1.5 2.7 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.15 ETN99642.1 - 7.6 6.1 9.4 0.14 11.6 0.8 2.4 4 0 0 4 4 4 0 MIZ/SP-RING zinc finger F_actin_cap_B PF01115.12 ETN99645.1 - 0.068 12.3 0.5 0.076 12.1 0.4 1.1 1 0 0 1 1 1 0 F-actin capping protein, beta subunit DUF2042 PF09743.4 ETN99645.1 - 0.07 12.4 0.1 0.084 12.1 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2042) DUF2413 PF10310.4 ETN99645.1 - 0.16 10.7 2.1 0.18 10.6 1.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Laminin_I PF06008.9 ETN99646.1 - 0.0079 15.5 6.8 0.0086 15.4 4.7 1.1 1 0 0 1 1 1 1 Laminin Domain I BTB_2 PF02214.17 ETN99646.1 - 0.16 12.2 4.4 0.12 12.5 1.7 1.7 1 1 1 2 2 2 0 BTB/POZ domain Tup_N PF08581.5 ETN99646.1 - 2.9 8.1 15.1 3.9 7.7 3.6 2.6 1 1 1 2 2 2 0 Tup N-terminal IncA PF04156.9 ETN99646.1 - 7.1 6.1 10.7 5.9 6.4 6.6 1.4 1 1 0 1 1 1 0 IncA protein DUF1183 PF06682.7 ETN99648.1 - 0.18 11.3 3.4 0.26 10.8 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) CASP_C PF08172.7 ETN99648.1 - 0.39 9.7 9.0 0.51 9.3 6.2 1.1 1 0 0 1 1 1 0 CASP C terminal FliE PF02049.13 ETN99648.1 - 2 8.4 7.2 2 8.5 2.5 2.2 2 1 0 2 2 2 0 Flagellar hook-basal body complex protein FliE NID PF07292.8 ETN99649.1 - 0.12 12.4 0.8 5.7 7.0 0.0 2.5 2 1 0 2 2 2 0 Nmi/IFP 35 domain (NID) DUF4337 PF14235.1 ETN99649.1 - 1.1 9.0 6.1 1.3 8.8 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) RabGAP-TBC PF00566.13 ETN99650.1 - 4.8e-22 78.4 0.7 5.4e-22 78.3 0.5 1.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Kelch_1 PF01344.20 ETN99652.1 - 9.4e-07 28.2 0.1 1.4e-05 24.5 0.0 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETN99652.1 - 1.9e-05 24.6 0.5 0.00044 20.3 0.1 2.6 1 1 1 2 2 2 1 Kelch motif Kelch_4 PF13418.1 ETN99652.1 - 0.0001 21.9 0.1 0.0016 18.1 0.0 2.5 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETN99652.1 - 0.00016 21.7 0.1 0.0016 18.5 0.0 2.6 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETN99652.1 - 0.003 17.2 0.1 0.041 13.6 0.1 2.6 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.1 ETN99652.1 - 0.13 12.2 0.0 2.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Kelch motif OmpH PF03938.9 ETN99652.1 - 0.14 12.0 2.4 0.2 11.5 1.7 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) WD40 PF00400.27 ETN99653.1 - 5.9e-29 98.8 0.2 6.3e-08 32.2 0.0 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETN99653.1 - 8.8e-09 34.0 0.1 0.0031 15.7 0.0 3.0 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 ETN99653.1 - 0.0012 17.7 0.1 0.0018 17.1 0.1 1.3 1 1 0 1 1 1 1 Coatomer WD associated region PQQ_2 PF13360.1 ETN99653.1 - 0.002 17.6 0.0 0.042 13.3 0.0 2.3 1 1 1 2 2 2 1 PQQ-like domain DPPIV_N PF00930.16 ETN99653.1 - 0.0028 16.3 0.1 1.4 7.4 0.0 3.4 1 1 2 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PQQ PF01011.16 ETN99653.1 - 0.0048 16.3 0.0 5.9 6.6 0.0 4.1 4 0 0 4 4 4 1 PQQ enzyme repeat Me-amine-dh_H PF06433.6 ETN99653.1 - 0.0057 15.3 0.0 0.077 11.6 0.0 2.3 2 1 0 2 2 2 1 Methylamine dehydrogenase heavy chain (MADH) Nucleoporin_N PF08801.6 ETN99653.1 - 0.02 13.6 2.2 2.3 6.8 0.1 2.9 1 1 1 3 3 3 0 Nup133 N terminal like Nbas_N PF15492.1 ETN99653.1 - 0.036 13.1 0.2 0.37 9.8 0.0 2.4 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.6 ETN99653.1 - 0.068 12.8 0.5 6.9 6.3 0.0 2.7 2 2 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF1652 PF07865.6 ETN99653.1 - 0.15 11.6 0.0 2.8 7.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1652) PD40 PF07676.7 ETN99653.1 - 0.43 10.3 2.5 1.4e+02 2.2 0.0 4.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat hGDE_central PF14702.1 ETN99654.1 - 0.065 12.4 3.8 0.082 12.0 2.6 1.1 1 0 0 1 1 1 0 central domain of human glycogen debranching enzyme C2 PF00168.25 ETN99654.1 - 0.08 12.7 0.4 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 C2 domain DUF3977 PF13122.1 ETN99654.1 - 0.53 10.1 4.1 0.62 9.9 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3977) Arb1 PF09692.5 ETN99655.1 - 0.0041 16.0 0.1 0.005 15.7 0.1 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 rve_2 PF13333.1 ETN99655.1 - 0.014 15.4 0.6 0.33 11.0 0.1 2.4 1 1 1 2 2 2 0 Integrase core domain DUF3643 PF12356.3 ETN99655.1 - 0.074 12.3 0.0 0.097 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3643) DUF2430 PF10353.4 ETN99656.1 - 0.054 13.6 0.1 0.095 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2430) DUF4485 PF14846.1 ETN99656.1 - 0.073 12.8 0.2 0.2 11.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4485) DUF2358 PF10184.4 ETN99656.1 - 0.091 12.6 0.5 0.54 10.2 0.0 2.3 1 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2358) XRCC4 PF06632.7 ETN99656.1 - 0.099 11.4 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Med6 PF04934.9 ETN99657.1 - 0.12 11.9 4.3 0.23 10.9 3.0 1.5 1 1 0 1 1 1 0 MED6 mediator sub complex component zf-TRAF PF02176.13 ETN99658.1 - 4.8e-05 23.6 7.6 4.8e-05 23.6 5.3 2.2 2 1 0 2 2 2 1 TRAF-type zinc finger HALZ PF02183.13 ETN99658.1 - 0.0027 17.4 5.3 0.0061 16.2 3.7 1.7 1 0 0 1 1 1 1 Homeobox associated leucine zipper DUF972 PF06156.8 ETN99658.1 - 0.033 14.5 5.2 0.077 13.3 3.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Sina PF03145.11 ETN99658.1 - 0.83 9.2 10.5 5 6.7 3.2 2.8 2 1 0 2 2 2 0 Seven in absentia protein family zf-TRAF PF02176.13 ETN99659.1 - 5.3e-06 26.7 3.3 5.3e-06 26.7 2.3 2.5 2 0 0 2 2 2 1 TRAF-type zinc finger zf-RING_2 PF13639.1 ETN99659.1 - 6.4 6.6 7.6 0.32 10.8 0.3 2.5 2 1 0 2 2 2 0 Ring finger domain Gar1 PF04410.9 ETN99661.1 - 0.37 10.2 8.9 0.03 13.7 3.0 1.5 2 0 0 2 2 2 0 Gar1/Naf1 RNA binding region Pex26 PF07163.7 ETN99661.1 - 1.1 8.1 3.9 1.1 8.0 2.7 1.3 1 1 0 1 1 1 0 Pex26 protein DUF4569 PF15133.1 ETN99661.1 - 3.9 6.7 11.2 4 6.7 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) WD40 PF00400.27 ETN99662.1 - 4.5e-18 64.3 0.4 5.3e-09 35.6 0.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN99662.1 - 5.3e-05 21.5 0.1 0.088 10.9 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Ricin_B_lectin PF00652.17 ETN99662.1 - 0.093 12.7 1.5 0.15 12.1 1.1 1.3 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain Flp_N PF03930.9 ETN99663.1 - 0.058 13.1 2.1 0.22 11.2 0.2 2.3 2 0 0 2 2 2 0 Recombinase Flp protein N-terminus PUB PF09409.5 ETN99663.1 - 0.17 11.6 4.7 0.06 13.1 0.5 2.4 3 1 0 3 3 3 0 PUB domain Suppressor_P21 PF11479.3 ETN99664.1 - 0.003 17.3 0.0 0.0063 16.2 0.0 1.5 1 0 0 1 1 1 1 RNA silencing suppressor P21 ArsR PF09824.4 ETN99664.1 - 0.011 15.0 0.2 0.055 12.7 0.0 2.2 3 0 0 3 3 3 0 ArsR transcriptional regulator Cofilin_ADF PF00241.15 ETN99665.1 - 0.026 14.4 0.7 0.036 13.9 0.5 1.2 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein Rapamycin_bind PF08771.6 ETN99665.1 - 0.055 13.5 0.3 0.091 12.8 0.2 1.3 1 0 0 1 1 1 0 Rapamycin binding domain TMEM247 PF15444.1 ETN99665.1 - 0.084 12.6 0.6 0.098 12.4 0.4 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 ETRAMP PF09716.5 ETN99665.1 - 0.52 10.2 9.5 54 3.8 6.6 2.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) NACHT PF05729.7 ETN99666.1 - 2.9e-09 36.7 0.0 3.2e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 NACHT domain WD40 PF00400.27 ETN99667.1 - 4.2e-33 112.0 12.0 4.3e-11 42.2 0.7 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN99667.1 - 5.6e-10 37.9 1.1 4.7e-05 21.7 0.1 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 V-ATPase_G PF03179.10 ETN99667.1 - 0.15 12.3 13.1 0.37 11.1 8.2 2.1 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit Kelch_1 PF01344.20 ETN99669.1 - 2.3e-07 30.2 2.5 2.3e-07 30.2 1.7 1.8 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETN99669.1 - 0.00039 20.4 1.8 0.001 19.1 0.8 2.1 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.1 ETN99669.1 - 0.0011 18.8 1.4 0.0026 17.6 0.5 1.9 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.10 ETN99669.1 - 0.0016 18.1 0.6 0.0044 16.7 0.4 1.7 1 0 0 1 1 1 1 Kelch motif Kelch_3 PF13415.1 ETN99669.1 - 0.0053 16.9 1.0 0.0096 16.0 0.3 1.7 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETN99669.1 - 0.063 13.0 0.2 0.18 11.5 0.2 1.8 1 0 0 1 1 1 0 Galactose oxidase, central domain DSL PF01414.14 ETN99670.1 - 0.02 14.8 10.1 1.2 9.2 2.5 2.7 2 0 0 2 2 2 0 Delta serrate ligand Cytochrom_B562 PF07361.6 ETN99672.1 - 0.011 16.0 0.1 0.04 14.3 0.0 2.0 1 0 0 1 1 1 0 Cytochrome b562 Ssl1 PF04056.9 ETN99672.1 - 0.053 13.1 1.3 1.1 8.8 0.1 2.5 2 0 0 2 2 2 0 Ssl1-like YMF19 PF02326.10 ETN99675.1 - 0.75 10.3 4.8 0.89 10.1 2.0 2.3 2 1 0 2 2 2 0 Plant ATP synthase F0 DNA_pol_E_B PF04042.11 ETN99676.1 - 0.0051 16.0 0.0 0.0068 15.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF1344 PF07076.6 ETN99676.1 - 0.1 12.1 0.1 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) Metalloenzyme PF01676.13 ETN99678.1 - 0.03 13.7 1.1 0.034 13.5 0.8 1.0 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF566 PF04484.7 ETN99678.1 - 0.096 12.1 1.5 0.11 11.9 1.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF566) Trypan_glycop PF00913.14 ETN99678.1 - 0.25 10.2 6.5 0.3 9.9 4.5 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) FGF-BP1 PF06473.7 ETN99678.1 - 0.39 10.2 5.9 0.44 10.1 4.1 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) MRI PF15325.1 ETN99678.1 - 0.98 10.4 8.2 0.64 11.0 3.4 1.8 1 1 1 2 2 2 0 Modulator of retrovirus infection TT_ORF1 PF02956.9 ETN99679.1 - 9.4 4.5 8.3 1.8 6.9 1.9 2.0 1 1 1 2 2 2 0 TT viral orf 1 Allexi_40kDa PF05549.6 ETN99680.1 - 0.0074 15.6 2.9 0.009 15.3 2.0 1.1 1 0 0 1 1 1 1 Allexivirus 40kDa protein Dysbindin PF04440.11 ETN99680.1 - 0.016 14.9 0.1 0.025 14.3 0.1 1.3 1 0 0 1 1 1 0 Dysbindin (Dystrobrevin binding protein 1) Granin PF01271.12 ETN99680.1 - 0.02 13.6 2.9 0.025 13.2 2.0 1.0 1 0 0 1 1 1 0 Granin (chromogranin or secretogranin) Tfb4 PF03850.9 ETN99680.1 - 0.065 12.4 3.8 0.077 12.2 2.6 1.1 1 0 0 1 1 1 0 Transcription factor Tfb4 Cortex-I_coil PF09304.5 ETN99680.1 - 0.2 11.6 5.1 0.29 11.2 3.5 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil DUF3768 PF12599.3 ETN99680.1 - 0.93 9.4 4.0 18 5.3 1.6 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3768) DUF45 PF01863.12 ETN99680.1 - 1.5 8.5 6.2 5.9 6.6 4.7 1.6 1 1 1 2 2 2 0 Protein of unknown function DUF45 CD36 PF01130.16 ETN99681.1 - 6.7e-30 103.7 4.7 8.9e-30 103.3 3.3 1.0 1 0 0 1 1 1 1 CD36 family Ank_3 PF13606.1 ETN99682.1 - 7.6e-09 34.9 0.1 0.005 16.9 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.25 ETN99682.1 - 1.4e-08 34.1 0.1 0.00073 19.2 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 ETN99682.1 - 1.7e-08 34.7 0.1 2.4e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETN99682.1 - 3e-08 33.8 0.2 3.7e-08 33.5 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETN99682.1 - 9.1e-06 25.7 0.3 0.00013 22.1 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SGT1 PF07093.6 ETN99683.1 - 0.062 11.6 11.0 0.068 11.5 7.6 1.2 1 0 0 1 1 1 0 SGT1 protein NOA36 PF06524.7 ETN99683.1 - 2 7.5 8.9 2.8 7.0 6.1 1.4 1 0 0 1 1 1 0 NOA36 protein Daxx PF03344.10 ETN99683.1 - 2.5 6.4 13.5 2.6 6.4 9.4 1.1 1 0 0 1 1 1 0 Daxx Family Shisa PF13908.1 ETN99685.1 - 0.024 14.8 1.4 0.039 14.1 0.1 1.9 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Ycf1 PF05758.7 ETN99685.1 - 0.14 9.8 6.8 0.13 9.9 4.7 1.1 1 0 0 1 1 1 0 Ycf1 DUF2606 PF10794.4 ETN99685.1 - 0.3 10.5 1.5 0.45 9.9 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2606) RRN3 PF05327.6 ETN99685.1 - 0.33 9.0 7.3 0.31 9.0 5.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TFIIF_alpha PF05793.7 ETN99685.1 - 0.37 9.1 21.7 0.4 9.0 15.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Mpp10 PF04006.7 ETN99685.1 - 0.48 8.7 28.0 0.55 8.5 19.4 1.1 1 0 0 1 1 1 0 Mpp10 protein DUF572 PF04502.8 ETN99685.1 - 0.59 9.3 15.8 0.64 9.1 11.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Daxx PF03344.10 ETN99685.1 - 0.67 8.3 29.2 0.83 8.0 20.2 1.1 1 0 0 1 1 1 0 Daxx Family Vfa1 PF08432.5 ETN99685.1 - 1.5 8.8 14.3 2.1 8.3 9.9 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 MIP-T3 PF10243.4 ETN99685.1 - 1.6 7.0 18.1 1.8 6.9 12.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Spore_coat_CotO PF14153.1 ETN99685.1 - 3.4 7.0 13.9 4.7 6.6 9.7 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Nop14 PF04147.7 ETN99685.1 - 4.5 5.0 28.3 5.3 4.8 19.6 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.10 ETN99685.1 - 7.1 5.1 8.8 7.6 5.0 6.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein YL1 PF05764.8 ETN99685.1 - 9 5.8 23.1 11 5.5 16.0 1.2 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.9 ETN99685.1 - 9.1 4.1 20.5 9.8 4.0 14.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Kelch_1 PF01344.20 ETN99687.1 - 2.2e-05 23.8 2.3 0.00081 18.8 0.2 3.2 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETN99687.1 - 5.2e-05 22.8 2.7 0.18 11.5 0.1 4.7 5 1 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETN99687.1 - 0.00042 20.0 0.6 0.074 12.8 0.0 3.2 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETN99687.1 - 0.004 17.0 0.1 0.17 11.8 0.1 2.9 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETN99687.1 - 0.012 15.7 0.2 2.5 8.4 0.1 3.6 3 1 0 3 3 3 0 Kelch motif TLD PF07534.11 ETN99687.1 - 0.032 14.2 1.6 0.061 13.3 0.1 2.0 1 1 2 3 3 3 0 TLD HAP1_N PF04849.8 ETN99688.1 - 0.01 14.8 12.6 0.017 14.0 8.7 1.5 1 1 0 1 1 1 1 HAP1 N-terminal conserved region CENP-H PF05837.7 ETN99688.1 - 0.21 11.7 12.7 0.29 11.3 8.8 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Viral_P18 PF04521.8 ETN99688.1 - 1 8.7 4.4 1 8.8 2.6 1.4 1 1 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein DUF3573 PF12097.3 ETN99688.1 - 1.3 7.5 8.7 1.3 7.5 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF948 PF06103.6 ETN99688.1 - 1.7 8.5 5.0 2.1 8.2 3.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 ETN99688.1 - 2.7 7.5 13.5 3 7.3 9.3 1.1 1 0 0 1 1 1 0 IncA protein CHD5 PF04420.9 ETN99688.1 - 6.7 6.3 8.3 30 4.2 5.7 2.0 1 1 0 1 1 1 0 CHD5-like protein zf-CpG_bind_C PF12269.3 ETN99688.1 - 9.6 5.5 12.1 10 5.5 8.4 1.0 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain DUF258 PF03193.11 ETN99689.1 - 8.2e-06 25.1 1.2 4.8e-05 22.6 0.8 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 ETN99689.1 - 4.7e-05 23.3 0.6 0.00012 22.0 0.2 1.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.22 ETN99689.1 - 5.9e-05 23.3 0.1 0.00011 22.4 0.1 1.4 1 0 0 1 1 1 1 ABC transporter T2SE PF00437.15 ETN99689.1 - 0.0011 17.9 0.1 0.0012 17.8 0.1 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF815 PF05673.8 ETN99689.1 - 0.0033 16.3 0.1 0.005 15.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.1 ETN99689.1 - 0.005 16.3 0.1 0.0099 15.3 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain PhoH PF02562.11 ETN99689.1 - 0.0051 16.0 0.2 0.0073 15.5 0.2 1.2 1 0 0 1 1 1 1 PhoH-like protein Miro PF08477.8 ETN99689.1 - 0.0056 17.1 0.1 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 ETN99689.1 - 0.0075 16.1 2.5 0.63 9.8 0.0 2.5 2 1 1 3 3 2 1 Dynamin family G-alpha PF00503.15 ETN99689.1 - 0.017 13.8 0.1 0.02 13.5 0.1 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_25 PF13481.1 ETN99689.1 - 0.027 13.8 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain MCM PF00493.18 ETN99689.1 - 0.042 12.6 0.1 0.058 12.1 0.1 1.2 1 0 0 1 1 1 0 MCM2/3/5 family Zeta_toxin PF06414.7 ETN99689.1 - 0.043 12.8 0.1 0.065 12.3 0.1 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 ETN99689.1 - 0.044 13.7 0.1 0.079 12.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 ETN99689.1 - 0.046 13.4 0.1 0.084 12.6 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 ETN99689.1 - 0.048 13.0 0.2 0.13 11.6 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein Septin PF00735.13 ETN99689.1 - 0.051 12.5 0.2 0.084 11.8 0.1 1.3 1 0 0 1 1 1 0 Septin VirE PF05272.6 ETN99689.1 - 0.073 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E AAA_23 PF13476.1 ETN99689.1 - 0.075 13.3 0.3 0.12 12.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 ETN99689.1 - 0.085 12.7 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 ETN99689.1 - 0.092 12.9 0.1 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.4 ETN99689.1 - 0.11 11.0 0.3 0.17 10.5 0.2 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.13 ETN99689.1 - 0.13 11.6 0.1 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.1 ETN99689.1 - 0.15 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain RNase_T PF00929.19 ETN99691.1 - 2.2e-07 31.3 0.0 4.7e-07 30.2 0.0 1.5 2 0 0 2 2 2 1 Exonuclease Trypan_PARP PF05887.6 ETN99691.1 - 0.66 9.7 4.7 0.99 9.2 3.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PDR_CDR PF06422.7 ETN99694.1 - 0.18 11.4 2.6 0.32 10.6 1.8 1.4 1 0 0 1 1 1 0 CDR ABC transporter Med2 PF11214.3 ETN99694.1 - 0.29 11.1 5.6 0.1 12.6 2.0 1.6 1 1 1 2 2 2 0 Mediator complex subunit 2 PEX11 PF05648.9 ETN99694.1 - 2.6 7.2 6.0 3.3 6.9 3.9 1.6 1 1 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) zf-TRAF PF02176.13 ETN99696.1 - 6.2e-07 29.6 0.9 1.6e-06 28.4 0.6 1.7 1 0 0 1 1 1 1 TRAF-type zinc finger CENP-F_leu_zip PF10473.4 ETN99696.1 - 0.0074 16.1 22.3 0.012 15.4 13.9 2.2 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_I PF06008.9 ETN99696.1 - 0.059 12.6 16.1 0.092 12.0 11.2 1.2 1 0 0 1 1 1 0 Laminin Domain I Rootletin PF15035.1 ETN99696.1 - 0.18 11.7 10.2 0.31 10.9 7.1 1.5 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF972 PF06156.8 ETN99696.1 - 0.26 11.6 15.8 0.036 14.4 6.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TSC22 PF01166.13 ETN99696.1 - 0.49 10.3 12.9 0.055 13.4 2.9 3.2 1 1 2 3 3 3 0 TSC-22/dip/bun family bZIP_1 PF00170.16 ETN99696.1 - 0.73 9.8 10.6 0.48 10.4 4.4 2.9 1 1 1 2 2 2 0 bZIP transcription factor DUF2681 PF10883.3 ETN99696.1 - 2.4 8.4 15.2 0.55 10.4 6.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) Atg14 PF10186.4 ETN99696.1 - 2.4 7.0 14.7 2.8 6.7 9.8 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 THP2 PF09432.5 ETN99696.1 - 4.9 7.0 12.4 1.2 8.9 3.4 2.2 1 1 1 2 2 2 0 Tho complex subunit THP2 DUF3450 PF11932.3 ETN99696.1 - 6.6 5.9 14.5 4.4 6.4 8.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Microtub_assoc PF07989.6 ETN99696.1 - 7.2 6.5 19.0 0.29 10.9 7.0 2.8 1 1 1 3 3 3 0 Microtubule associated Cep57_CLD_2 PF14197.1 ETN99696.1 - 7.4 6.6 15.6 4.2 7.3 4.9 3.3 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 TMEM18 PF14770.1 ETN99698.1 - 0.095 12.2 1.5 0.52 9.8 0.1 2.1 2 0 0 2 2 2 0 Transmembrane protein 18 Sedlin_N PF04628.8 ETN99698.1 - 0.61 9.9 4.1 0.97 9.2 0.2 2.3 1 1 1 2 2 2 0 Sedlin, N-terminal conserved region Suc_Fer-like PF06999.7 ETN99699.1 - 0.11 12.4 1.4 0.18 11.8 1.0 1.3 1 0 0 1 1 1 0 Sucrase/ferredoxin-like IncA PF04156.9 ETN99699.1 - 2.5 7.6 6.4 6.5 6.3 4.4 1.7 1 1 0 1 1 1 0 IncA protein Ribosomal_L50 PF10501.4 ETN99700.1 - 0.0006 19.7 0.5 0.0012 18.8 0.4 1.4 1 0 0 1 1 1 1 Ribosomal subunit 39S Syntaxin PF00804.20 ETN99700.1 - 0.0015 18.6 3.9 0.37 10.9 1.7 2.3 2 0 0 2 2 2 2 Syntaxin DUF2063 PF09836.4 ETN99700.1 - 0.019 14.9 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2063) Cauli_DNA-bind PF03310.8 ETN99700.1 - 0.027 14.3 4.9 1.9 8.3 1.3 2.1 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein DUF148 PF02520.12 ETN99700.1 - 0.088 12.5 4.5 1.6 8.5 2.1 2.4 1 1 1 2 2 2 0 Domain of unknown function DUF148 FlaC_arch PF05377.6 ETN99700.1 - 0.09 12.6 8.1 0.74 9.7 1.9 2.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DXP_synthase_N PF13292.1 ETN99700.1 - 0.096 11.5 1.1 0.11 11.4 0.8 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Mit_KHE1 PF10173.4 ETN99700.1 - 0.11 12.3 0.5 0.11 12.3 0.4 1.1 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Syntaxin-6_N PF09177.6 ETN99700.1 - 0.12 12.8 3.0 0.36 11.2 1.4 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal TBPIP PF07106.8 ETN99700.1 - 0.13 11.8 5.9 1.1 8.8 2.7 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ParA PF10609.4 ETN99700.1 - 0.13 12.1 0.4 0.22 11.4 0.2 1.6 1 1 0 1 1 1 0 ParA/MinD ATPase like DASH_Duo1 PF08651.5 ETN99700.1 - 0.17 11.4 4.2 4 7.0 0.9 2.7 2 1 1 3 3 3 0 DASH complex subunit Duo1 FlxA PF14282.1 ETN99700.1 - 0.22 11.4 4.2 0.09 12.7 1.4 1.5 2 0 0 2 2 1 0 FlxA-like protein Syntaxin_2 PF14523.1 ETN99700.1 - 0.3 11.1 4.7 0.79 9.7 2.2 1.9 1 1 1 2 2 2 0 Syntaxin-like protein LUC7 PF03194.10 ETN99700.1 - 0.34 10.4 3.6 0.38 10.2 2.5 1.0 1 0 0 1 1 1 0 LUC7 N_terminus Prefoldin_2 PF01920.15 ETN99700.1 - 0.44 10.3 6.3 0.34 10.6 1.4 2.5 1 1 2 3 3 3 0 Prefoldin subunit DUF948 PF06103.6 ETN99700.1 - 0.96 9.3 5.4 9 6.2 3.4 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HEAT PF02985.17 ETN99701.1 - 1.4e-06 27.9 0.0 0.0091 15.9 0.0 2.8 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.1 ETN99701.1 - 1.9e-05 24.8 0.0 0.00012 22.2 0.0 1.8 1 1 1 2 2 2 2 HEAT repeats CLASP_N PF12348.3 ETN99701.1 - 0.00088 18.6 0.3 0.0017 17.7 0.2 1.5 1 1 0 1 1 1 1 CLASP N terminal HEAT_EZ PF13513.1 ETN99701.1 - 0.0024 18.3 0.0 0.012 16.1 0.0 2.0 1 1 1 2 2 2 2 HEAT-like repeat DUF3137 PF11335.3 ETN99701.1 - 0.0031 17.1 0.2 0.0057 16.3 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3137) DUF3554 PF12074.3 ETN99701.1 - 0.0033 16.9 0.7 0.0085 15.5 0.3 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF3554) Inhibitor_I9 PF05922.11 ETN99701.1 - 0.067 13.7 0.0 0.11 13.0 0.0 1.6 1 1 0 1 1 1 0 Peptidase inhibitor I9 TIP120 PF08623.5 ETN99701.1 - 0.086 12.4 1.4 0.46 10.0 0.1 2.0 1 1 1 2 2 2 0 TATA-binding protein interacting (TIP20) UvrD-helicase PF00580.16 ETN99701.1 - 0.36 10.0 4.2 0.55 9.4 2.9 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain EF-hand_1 PF00036.27 ETN99702.1 - 0.0092 15.2 0.0 0.023 13.9 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 ETN99702.1 - 0.062 13.2 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain Copine PF07002.11 ETN99704.1 - 1e-23 83.6 0.1 5.8e-12 45.5 0.0 2.1 1 1 1 2 2 2 2 Copine Endotoxin_N PF03945.9 ETN99705.1 - 0.013 14.9 0.7 0.013 14.9 0.5 1.1 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain Med2 PF11214.3 ETN99705.1 - 0.082 12.9 0.2 0.099 12.6 0.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 2 TPR_11 PF13414.1 ETN99706.1 - 1.1e-11 44.1 4.1 7.9e-05 22.2 0.0 3.2 3 0 0 3 3 3 3 TPR repeat TPR_14 PF13428.1 ETN99706.1 - 1.6e-09 37.5 0.1 0.033 14.8 0.0 4.1 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETN99706.1 - 5.4e-07 29.3 7.6 0.023 14.8 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETN99706.1 - 7.5e-07 28.5 0.6 0.17 11.8 0.0 4.4 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETN99706.1 - 6.2e-06 25.9 0.2 0.00012 21.8 0.4 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETN99706.1 - 1e-05 25.7 0.0 0.23 11.8 0.0 2.8 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETN99706.1 - 1.7e-05 24.2 0.9 0.0041 16.6 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETN99706.1 - 2.5e-05 24.8 0.1 0.24 12.1 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETN99706.1 - 8.7e-05 22.3 1.6 0.0072 16.1 0.0 3.1 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.1 ETN99706.1 - 0.00035 20.4 4.9 0.12 12.3 0.1 3.4 1 1 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETN99706.1 - 0.005 16.5 0.6 2 8.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETN99706.1 - 0.0091 15.7 2.5 0.53 10.1 0.0 3.7 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 ETN99706.1 - 0.012 15.7 6.2 1.1 9.3 0.0 3.0 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETN99706.1 - 0.021 15.2 2.1 2.1 9.0 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat FlbT PF07378.6 ETN99706.1 - 0.046 13.5 0.1 6.1 6.7 0.1 2.2 2 0 0 2 2 2 0 Flagellar protein FlbT TAF1_subA PF14929.1 ETN99707.1 - 0.0033 15.9 0.8 0.0037 15.7 0.5 1.1 1 0 0 1 1 1 1 TAF RNA Polymerase I subunit A GlcNAc_2-epim PF07221.6 ETN99707.1 - 0.038 12.9 0.0 0.047 12.7 0.0 1.1 1 0 0 1 1 1 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) RVT_3 PF13456.1 ETN99707.1 - 0.048 13.4 0.3 0.087 12.6 0.2 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like TPR_11 PF13414.1 ETN99709.1 - 0.0002 20.9 2.0 0.00027 20.5 0.5 1.9 2 1 1 3 3 3 1 TPR repeat TPR_2 PF07719.12 ETN99709.1 - 0.59 10.1 2.4 2.1 8.4 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETN99710.1 - 6.2e-06 25.5 0.6 6.2e-06 25.5 0.4 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETN99710.1 - 1.2e-05 24.9 2.7 2.2e-05 24.0 1.9 1.4 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 ETN99710.1 - 1.6e-05 24.4 0.9 4.2e-05 23.1 0.3 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETN99710.1 - 0.00054 19.8 1.2 0.00089 19.1 0.3 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETN99710.1 - 0.0014 18.2 0.5 0.0088 15.7 0.2 2.5 2 1 1 3 3 3 1 Tetratricopeptide repeat FAT PF02259.18 ETN99710.1 - 0.0062 15.5 2.8 0.021 13.8 0.0 2.3 2 1 0 2 2 2 1 FAT domain TPR_19 PF14559.1 ETN99710.1 - 0.017 15.4 0.2 0.048 14.0 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETN99710.1 - 0.049 13.4 0.7 0.72 9.8 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETN99710.1 - 0.049 13.5 0.9 0.1 12.4 0.2 1.9 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Apc3 PF12895.2 ETN99710.1 - 0.05 13.7 0.9 0.082 13.0 0.6 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 ETN99710.1 - 0.06 14.0 0.0 0.29 11.8 0.0 2.1 2 1 0 2 2 2 0 Tetratricopeptide repeat PABP PF00658.13 ETN99712.1 - 2.7e-23 81.4 3.1 6.3e-23 80.2 2.2 1.6 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain zf-TRAF PF02176.13 ETN99712.1 - 0.00047 20.4 2.0 0.00047 20.4 1.4 2.2 2 1 0 2 2 2 1 TRAF-type zinc finger AKAP7_RIRII_bdg PF10470.4 ETN99712.1 - 0.035 13.9 0.1 0.14 12.0 0.0 2.1 1 0 0 1 1 1 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein PDEase_I PF00233.14 ETN99713.1 - 5.1e-42 144.2 5.3 2.8e-31 109.1 2.9 2.3 1 1 1 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase MMR_HSR1 PF01926.18 ETN99715.1 - 8.4e-06 25.7 0.0 1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 ETN99715.1 - 9.9e-06 24.8 0.0 1.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 AIG1 family KaiC PF06745.8 ETN99715.1 - 0.0048 16.0 0.0 0.0097 15.0 0.0 1.5 1 1 1 2 2 2 1 KaiC RNA_helicase PF00910.17 ETN99715.1 - 0.0051 16.9 0.0 0.016 15.3 0.0 1.8 1 1 1 2 2 2 1 RNA helicase AAA_22 PF13401.1 ETN99715.1 - 0.017 15.2 0.0 0.034 14.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.4 ETN99715.1 - 0.045 12.6 0.0 0.07 12.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Sigma54_activat PF00158.21 ETN99715.1 - 0.051 13.0 0.0 0.064 12.7 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 ETN99715.1 - 0.073 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 ETN99715.1 - 0.075 13.3 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 ETN99715.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Septin PF00735.13 ETN99715.1 - 0.14 11.1 0.0 0.25 10.3 0.0 1.4 1 1 0 1 1 1 0 Septin IstB_IS21 PF01695.12 ETN99715.1 - 0.15 11.4 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2606 PF10794.4 ETN99716.1 - 0.11 11.9 0.4 0.16 11.4 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2606) DUF929 PF06053.6 ETN99716.1 - 0.16 11.0 0.5 0.14 11.2 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF929) DUF2304 PF10066.4 ETN99716.1 - 0.17 11.7 3.7 0.31 10.9 2.6 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) ASFV_J13L PF05568.6 ETN99716.1 - 0.17 11.3 0.6 0.16 11.4 0.4 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein EzrA PF06160.7 ETN99716.1 - 0.35 8.9 2.9 0.44 8.6 2.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF3139 PF11337.3 ETN99716.1 - 0.77 10.0 2.9 1.3 9.3 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) ODV-E18 PF10717.4 ETN99716.1 - 0.99 8.8 5.9 0.52 9.7 2.6 1.7 1 1 1 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 PAS_8 PF13188.1 ETN99717.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 PAS domain 7TM_GPCR_Srw PF10324.4 ETN99718.1 - 0.00016 20.8 6.3 0.0002 20.5 4.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Frag1 PF10277.4 ETN99718.1 - 0.13 11.6 3.0 0.18 11.2 2.1 1.2 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family EphA2_TM PF14575.1 ETN99718.1 - 0.32 11.4 4.1 0.37 11.2 0.1 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Oxidored_q3 PF00499.15 ETN99718.1 - 0.69 9.6 7.0 1.2 8.9 4.8 1.3 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Kelch_6 PF13964.1 ETN99719.1 - 2.8e-06 27.2 0.2 0.00039 20.4 0.0 2.6 1 1 1 2 2 2 1 Kelch motif Kelch_1 PF01344.20 ETN99719.1 - 1.4e-05 24.5 0.1 7.6e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.1 ETN99719.1 - 3.2e-05 23.6 0.0 0.0095 15.6 0.0 2.5 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETN99719.1 - 0.021 14.9 0.0 0.047 13.8 0.0 1.6 1 0 0 1 1 1 0 Galactose oxidase, central domain Kelch_5 PF13854.1 ETN99719.1 - 0.18 11.7 0.6 0.48 10.4 0.1 2.0 3 0 0 3 3 3 0 Kelch motif WD40 PF00400.27 ETN99720.1 - 0.15 11.9 0.4 2.7 8.0 0.2 2.3 1 1 0 1 1 1 0 WD domain, G-beta repeat 3-HAO PF06052.7 ETN99721.1 - 1.7e-46 157.3 0.2 5e-46 155.8 0.1 1.8 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 ETN99721.1 - 1.9e-05 24.0 0.2 0.0015 17.9 0.1 2.8 3 0 0 3 3 3 1 Cupin domain AraC_binding PF02311.14 ETN99721.1 - 0.0064 16.1 0.1 0.023 14.3 0.1 1.9 3 0 0 3 3 3 1 AraC-like ligand binding domain Cupin_1 PF00190.17 ETN99721.1 - 0.044 13.2 0.1 0.46 9.9 0.0 2.1 2 0 0 2 2 2 0 Cupin Cupin_6 PF12852.2 ETN99721.1 - 0.077 12.6 0.0 2.4 7.7 0.0 2.1 2 0 0 2 2 2 0 Cupin DUF1686 PF07937.6 ETN99722.1 - 0.13 11.8 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1686) PDDEXK_4 PF14281.1 ETN99722.1 - 0.34 10.7 9.7 0.44 10.3 6.7 1.2 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily DUF3654 PF12376.3 ETN99723.1 - 0.046 13.5 0.8 0.092 12.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3654) Tubulin_C PF03953.12 ETN99724.1 - 3.7e-06 27.0 0.0 5e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain DUF262 PF03235.9 ETN99725.1 - 1.6 8.6 12.8 2.1 8.2 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 Caldesmon PF02029.10 ETN99725.1 - 3 6.1 20.0 4 5.7 13.8 1.2 1 0 0 1 1 1 0 Caldesmon Utp13 PF08625.6 ETN99726.1 - 0.013 15.1 2.3 0.71 9.5 1.6 2.2 1 1 0 1 1 1 0 Utp13 specific WD40 associated domain DUF2605 PF10792.4 ETN99726.1 - 0.22 11.2 1.6 1.9 8.2 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2605) TPR_8 PF13181.1 ETN99727.1 - 0.0032 17.1 0.4 0.0072 16.0 0.2 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat CENP-T PF15511.1 ETN99727.1 - 4.2 6.5 11.6 4 6.5 8.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF605 PF04652.11 ETN99727.1 - 7.4 5.8 12.0 8.3 5.6 8.3 1.2 1 0 0 1 1 1 0 Vta1 like WD40 PF00400.27 ETN99728.1 - 1.9e-07 30.7 1.2 1.5e-06 27.8 0.1 2.4 2 1 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETN99728.1 - 0.042 11.9 0.0 0.043 11.9 0.0 1.0 1 0 0 1 1 1 0 Nucleoporin Nup120/160 TPR_12 PF13424.1 ETN99729.1 - 1.3e-34 117.9 0.2 2.9e-19 68.7 0.1 2.7 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETN99729.1 - 8.1e-27 92.3 0.0 2.1e-10 40.1 0.0 3.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETN99729.1 - 3.1e-22 77.2 9.1 6e-11 41.4 0.8 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETN99729.1 - 4.7e-21 72.8 0.0 4.6e-06 26.0 0.0 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETN99729.1 - 1.4e-20 72.7 1.1 6.7e-17 60.9 0.1 2.1 1 1 1 2 2 2 2 TPR repeat TPR_8 PF13181.1 ETN99729.1 - 2.5e-15 55.0 8.9 4.1e-08 32.4 0.7 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETN99729.1 - 5e-15 54.1 4.9 1.1e-06 28.1 0.1 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETN99729.1 - 1.1e-08 34.5 0.5 0.00081 19.3 0.0 3.4 4 1 0 4 4 3 2 Tetratricopeptide repeat Apc3 PF12895.2 ETN99729.1 - 1.1e-06 28.6 1.0 0.00023 21.2 0.2 1.9 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 ETN99729.1 - 1.6e-05 24.5 1.4 0.026 14.4 0.1 3.1 3 0 0 3 3 3 1 PPR repeat TPR_16 PF13432.1 ETN99729.1 - 2.8e-05 24.6 0.0 0.038 14.6 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat MIT PF04212.13 ETN99729.1 - 0.00012 21.8 2.5 0.8 9.6 0.1 3.0 2 1 1 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_14 PF13428.1 ETN99729.1 - 0.00014 22.1 0.0 1.3 9.8 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETN99729.1 - 0.00097 19.4 0.0 1.3 9.4 0.0 2.3 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETN99729.1 - 0.0013 19.0 0.0 0.85 10.2 0.0 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETN99729.1 - 0.0058 15.8 0.0 0.41 9.9 0.0 2.9 3 1 0 3 3 3 1 SHNi-TPR KH_4 PF13083.1 ETN99729.1 - 0.037 13.6 0.0 0.066 12.8 0.0 1.6 1 0 0 1 1 1 0 KH domain Fis1_TPR_C PF14853.1 ETN99729.1 - 0.042 13.7 1.2 2.1 8.2 0.2 2.8 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Pep3_Vps18 PF05131.9 ETN99729.1 - 0.055 12.8 0.1 0.56 9.6 0.0 2.3 3 0 0 3 3 3 0 Pep3/Vps18/deep orange family PPR_2 PF13041.1 ETN99729.1 - 0.085 12.8 0.1 3.4 7.7 0.0 2.3 2 0 0 2 2 2 0 PPR repeat family Musclin PF11037.3 ETN99729.1 - 0.15 11.6 0.0 9 5.9 0.0 2.6 3 0 0 3 3 3 0 Insulin-resistance promoting peptide in skeletal muscle DUF627 PF04781.7 ETN99729.1 - 0.18 11.4 0.5 1.7 8.3 0.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF627) TPR_3 PF07720.7 ETN99729.1 - 0.67 9.8 0.1 0.67 9.8 0.1 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat HEAT PF02985.17 ETN99730.1 - 0.002 18.0 0.0 0.0049 16.8 0.0 1.7 1 0 0 1 1 1 1 HEAT repeat HEAT_2 PF13646.1 ETN99730.1 - 0.016 15.5 0.0 0.19 12.0 0.0 2.1 2 0 0 2 2 2 0 HEAT repeats NLE PF08154.7 ETN99730.1 - 0.027 14.4 0.9 9.3 6.3 0.0 3.2 2 1 1 3 3 3 0 NLE (NUC135) domain HEAT_2 PF13646.1 ETN99732.1 - 9.3e-12 45.0 0.0 0.055 13.7 0.0 5.1 5 1 0 5 5 5 3 HEAT repeats HEAT PF02985.17 ETN99732.1 - 1e-07 31.4 7.0 0.2 11.8 0.0 8.7 10 1 1 11 11 11 2 HEAT repeat HEAT_EZ PF13513.1 ETN99732.1 - 8.7e-05 22.8 0.0 20 5.8 0.0 5.9 7 0 0 7 7 7 1 HEAT-like repeat RUN PF02759.14 ETN99732.1 - 0.04 13.6 3.0 3.3 7.4 0.0 4.1 3 1 1 4 4 4 0 RUN domain DinB PF05163.7 ETN99732.1 - 0.11 12.2 0.1 0.36 10.5 0.0 1.9 2 0 0 2 2 2 0 DinB family DUF2543 PF10820.3 ETN99732.1 - 0.21 11.6 3.3 1.5 8.8 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2543) DUF4401 PF14351.1 ETN99733.1 - 0.0011 18.0 5.7 0.0014 17.6 4.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) DUF805 PF05656.9 ETN99733.1 - 0.032 14.0 7.1 0.94 9.3 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF805) DUF1772 PF08592.6 ETN99733.1 - 0.046 13.4 3.8 0.98 9.1 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Cytochrom_B_C PF00032.12 ETN99733.1 - 0.059 13.5 7.6 0.091 12.9 2.6 2.3 1 1 1 2 2 2 0 Cytochrome b(C-terminal)/b6/petD YfhO PF09586.5 ETN99733.1 - 0.2 9.6 3.5 0.25 9.2 2.4 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF3488 PF11992.3 ETN99733.1 - 0.25 9.9 3.2 0.18 10.4 0.1 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF3488) DUF4013 PF13197.1 ETN99733.1 - 0.28 10.5 10.9 0.17 11.2 2.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4013) 7TMR-DISM_7TM PF07695.6 ETN99733.1 - 0.35 10.5 13.7 1.1 8.8 9.2 1.6 1 1 0 1 1 1 0 7TM diverse intracellular signalling VIT1 PF01988.14 ETN99733.1 - 0.37 10.2 1.9 12 5.2 0.3 2.1 2 0 0 2 2 2 0 VIT family 5TM-5TMR_LYT PF07694.7 ETN99733.1 - 0.39 10.0 4.7 0.14 11.4 1.6 1.5 2 0 0 2 2 2 0 5TMR of 5TMR-LYT GP41 PF00517.12 ETN99733.1 - 0.54 9.7 2.0 1.7 8.1 1.0 1.9 2 0 0 2 2 2 0 Retroviral envelope protein DUF2975 PF11188.3 ETN99733.1 - 0.7 9.6 10.6 0.4 10.3 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) MARVEL PF01284.18 ETN99733.1 - 1.1 9.0 12.0 11 5.7 8.3 2.2 1 1 0 1 1 1 0 Membrane-associating domain DUF4231 PF14015.1 ETN99733.1 - 1.7 8.6 7.2 0.58 10.1 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) DUF4181 PF13789.1 ETN99733.1 - 1.9 8.4 5.6 0.78 9.6 0.5 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4181) DUF485 PF04341.7 ETN99733.1 - 2.6 7.8 6.9 1.2 8.9 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function, DUF485 DUF4131 PF13567.1 ETN99733.1 - 4 6.8 11.1 0.88 8.9 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Colicin_V PF02674.11 ETN99733.1 - 4.6 7.0 11.1 0.081 12.7 0.9 2.3 1 1 1 2 2 2 0 Colicin V production protein TcpE PF12648.2 ETN99733.1 - 5.2 7.2 11.5 3.4 7.8 2.9 2.7 1 1 2 3 3 3 0 TcpE family DUF2910 PF11139.3 ETN99733.1 - 6.5 5.8 8.0 7.7 5.5 0.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF2910) NfeD PF01957.13 ETN99733.1 - 7.8 6.6 6.3 30 4.7 3.4 2.4 1 1 2 3 3 3 0 NfeD-like C-terminal, partner-binding ABC2_membrane_3 PF12698.2 ETN99733.1 - 9 5.2 10.6 12 4.7 7.4 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1796 PF08795.5 ETN99734.1 - 0.076 12.6 0.2 0.081 12.5 0.1 1.0 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) zf-BED PF02892.10 ETN99734.1 - 0.11 12.2 0.6 0.23 11.2 0.1 1.9 2 0 0 2 2 2 0 BED zinc finger zf-RING_2 PF13639.1 ETN99734.1 - 0.11 12.3 1.8 0.12 12.2 0.0 2.0 2 1 0 2 2 2 0 Ring finger domain WD40 PF00400.27 ETN99735.1 - 3.2e-30 102.9 12.2 3.5e-11 42.5 0.0 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN99735.1 - 6.9e-09 34.3 0.1 0.0011 17.2 0.0 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETN99735.1 - 0.052 13.4 0.0 1.8 8.5 0.0 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF3601) BBS2_Mid PF14783.1 ETN99735.1 - 0.11 12.2 0.0 6.9 6.5 0.0 2.5 1 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region E1-E2_ATPase PF00122.15 ETN99737.1 - 4e-15 55.4 0.1 8.1e-14 51.2 0.1 2.2 1 1 0 1 1 1 1 E1-E2 ATPase NST1 PF13945.1 ETN99737.1 - 7.6 6.5 24.8 1.3 9.0 6.4 2.3 2 0 0 2 2 2 0 Salt tolerance down-regulator Myco_haema PF05692.7 ETN99738.1 - 0.063 11.9 1.0 0.083 11.5 0.7 1.1 1 0 0 1 1 1 0 Mycoplasma haemagglutinin DUF1655 PF07868.6 ETN99738.1 - 0.12 12.4 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1655) Imm35 PF15581.1 ETN99738.1 - 0.12 12.3 1.1 0.18 11.8 0.1 1.7 1 1 1 2 2 2 0 Immunity protein 35 Spc42p PF11544.3 ETN99738.1 - 1.5 8.7 4.6 1.9 8.4 0.8 2.1 2 0 0 2 2 2 0 Spindle pole body component Spc42p DUF789 PF05623.7 ETN99740.1 - 0.0043 16.5 3.9 0.0049 16.3 2.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF789) FCP1_C PF09309.5 ETN99740.1 - 0.0066 15.7 2.1 0.0078 15.5 1.4 1.1 1 0 0 1 1 1 1 FCP1, C-terminal ScpA_ScpB PF02616.9 ETN99740.1 - 0.0099 15.4 0.9 0.012 15.2 0.6 1.1 1 0 0 1 1 1 1 ScpA/B protein LMBR1 PF04791.11 ETN99740.1 - 0.036 12.6 1.9 0.043 12.3 1.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Mem_trans PF03547.13 ETN99740.1 - 0.15 10.2 0.7 0.15 10.3 0.5 1.1 1 0 0 1 1 1 0 Membrane transport protein Serinc PF03348.10 ETN99740.1 - 0.2 10.3 0.5 0.21 10.2 0.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) CDC45 PF02724.9 ETN99740.1 - 0.42 8.5 6.4 0.47 8.4 4.4 1.2 1 0 0 1 1 1 0 CDC45-like protein TSGP1 PF07771.6 ETN99740.1 - 1.2 9.0 6.5 1.9 8.3 4.5 1.2 1 0 0 1 1 1 0 Tick salivary peptide group 1 YqfQ PF14181.1 ETN99740.1 - 2.6 8.0 6.6 3.7 7.5 4.6 1.2 1 0 0 1 1 1 0 YqfQ-like protein Cucumo_2B PF03263.8 ETN99740.1 - 2.6 8.3 7.2 0.42 10.9 2.2 1.7 1 1 1 2 2 2 0 Cucumovirus protein 2B WD40 PF00400.27 ETN99741.1 - 0.00023 20.8 0.0 0.001 18.8 0.0 2.1 2 0 0 2 2 2 1 WD domain, G-beta repeat Peptidase_C14 PF00656.17 ETN99742.1 - 6.8e-14 52.1 0.5 1.2e-13 51.3 0.3 1.3 1 0 0 1 1 1 1 Caspase domain DUF2599 PF10783.4 ETN99742.1 - 0.11 13.1 0.1 4.4 8.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2599) Med29 PF11568.3 ETN99743.1 - 3.8e-05 23.7 2.1 4.8e-05 23.4 1.5 1.2 1 0 0 1 1 1 1 Mediator complex subunit 29 DUF4175 PF13779.1 ETN99743.1 - 0.0036 15.0 3.8 0.0046 14.7 2.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) DUF4315 PF14193.1 ETN99743.1 - 0.0089 15.9 2.7 0.016 15.1 1.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4315) DUF230 PF03003.11 ETN99743.1 - 0.027 13.9 0.1 0.056 12.9 0.0 1.7 1 1 1 2 2 2 0 Poxvirus proteins of unknown function Fib_alpha PF08702.5 ETN99743.1 - 0.2 11.7 6.2 0.26 11.4 4.3 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family WD40 PF00400.27 ETN99744.1 - 2e-44 147.8 4.6 3.3e-13 48.9 0.1 4.0 4 0 0 4 4 4 4 WD domain, G-beta repeat PD40 PF07676.7 ETN99744.1 - 1.3e-05 24.7 1.1 4.1 7.1 0.0 4.4 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETN99744.1 - 1.9e-05 23.0 0.0 0.12 10.5 0.0 2.9 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETN99744.1 - 8.9e-05 21.4 3.8 0.14 10.9 0.1 3.0 1 1 2 3 3 3 2 Nup133 N terminal like PQQ_2 PF13360.1 ETN99744.1 - 0.00016 21.2 0.1 0.059 12.8 0.1 2.5 1 1 1 2 2 2 2 PQQ-like domain Proteasome_A_N PF10584.4 ETN99744.1 - 0.00056 19.1 4.1 3.6 6.9 0.0 4.5 4 0 0 4 4 4 1 Proteasome subunit A N-terminal signature Gmad1 PF10647.4 ETN99744.1 - 0.0023 17.3 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain TolB_N PF04052.8 ETN99744.1 - 0.015 15.3 0.0 10 6.2 0.0 3.0 3 0 0 3 3 3 0 TolB amino-terminal domain BBS2_Mid PF14783.1 ETN99744.1 - 0.029 14.1 0.2 6.7 6.5 0.1 3.0 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region DUF3732 PF12532.3 ETN99744.1 - 0.036 13.5 0.4 5.8 6.3 0.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3732) PLD_C PF12357.3 ETN99744.1 - 0.04 13.4 0.0 19 4.8 0.0 3.1 2 1 1 3 3 3 0 Phospholipase D C terminal SGL PF08450.7 ETN99744.1 - 0.11 11.8 0.0 11 5.2 0.0 2.3 1 1 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region DUF3312 PF11768.3 ETN99744.1 - 0.16 10.1 0.0 4.8 5.2 0.0 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3312) OSCP PF00213.13 ETN99745.1 - 0.12 12.2 0.4 0.17 11.7 0.3 1.2 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit CUE PF02845.11 ETN99745.1 - 0.21 11.0 1.0 0.32 10.5 0.0 1.9 2 0 0 2 2 2 0 CUE domain DUF2833 PF11090.3 ETN99746.1 - 0.053 13.6 0.3 0.16 12.1 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2833) RRP14 PF15459.1 ETN99747.1 - 0.088 12.8 0.3 0.18 11.9 0.0 1.6 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 MIP-T3 PF10243.4 ETN99749.1 - 0.05 12.0 33.9 0.051 12.0 23.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 TFIIF_alpha PF05793.7 ETN99749.1 - 0.38 9.0 41.2 0.42 8.9 28.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CENP-T PF15511.1 ETN99749.1 - 1.8 7.7 14.2 1.8 7.6 9.9 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF2201_N PF13203.1 ETN99749.1 - 3.7 6.6 13.9 4.2 6.4 9.6 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain Gti1_Pac2 PF09729.4 ETN99749.1 - 4 7.2 12.1 5.3 6.8 8.4 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family Atrophin-1 PF03154.10 ETN99749.1 - 4.4 5.3 21.0 4.9 5.1 14.5 1.2 1 0 0 1 1 1 0 Atrophin-1 family FancD2 PF14631.1 ETN99749.1 - 5 4.0 13.9 6.1 3.7 9.6 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Tim54 PF11711.3 ETN99749.1 - 5.5 5.4 15.6 6.7 5.1 10.8 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4175 PF13779.1 ETN99749.1 - 6.3 4.3 19.1 7.3 4.1 13.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CDC45 PF02724.9 ETN99749.1 - 6.5 4.6 29.6 7 4.5 20.5 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 ETN99749.1 - 7.8 5.1 31.3 8.6 4.9 21.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TFIIF_alpha PF05793.7 ETN99751.1 - 0.0055 15.1 33.7 0.0065 14.8 23.3 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF572 PF04502.8 ETN99751.1 - 0.035 13.3 26.2 0.042 13.0 18.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) CENP-T PF15511.1 ETN99751.1 - 0.12 11.6 15.6 0.14 11.3 10.8 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T MIP-T3 PF10243.4 ETN99751.1 - 0.25 9.7 31.7 0.28 9.5 22.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF966 PF06136.8 ETN99751.1 - 0.27 10.6 23.6 0.32 10.3 16.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Menin PF05053.8 ETN99751.1 - 0.39 8.8 11.6 0.44 8.6 8.1 1.1 1 0 0 1 1 1 0 Menin Daxx PF03344.10 ETN99751.1 - 0.56 8.6 26.7 0.6 8.5 18.5 1.0 1 0 0 1 1 1 0 Daxx Family CDC27 PF09507.5 ETN99751.1 - 1.5 7.9 34.6 1.8 7.6 24.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Suf PF05843.9 ETN99751.1 - 2 8.0 11.1 2.6 7.7 7.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SOBP PF15279.1 ETN99751.1 - 9 6.5 9.1 11 6.3 6.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein MIP-T3 PF10243.4 ETN99752.1 - 0.3 9.4 46.4 0.34 9.3 32.2 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1675 PF07897.6 ETN99752.1 - 0.35 10.6 38.2 0.41 10.4 26.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) LMBR1 PF04791.11 ETN99752.1 - 0.36 9.3 9.9 0.84 8.1 6.8 1.6 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF2413 PF10310.4 ETN99752.1 - 0.88 8.3 23.7 1.3 7.7 16.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) WD40 PF00400.27 ETN99753.1 - 3e-15 55.4 0.6 3.9e-10 39.2 0.0 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat Birna_RdRp PF04197.7 ETN99754.1 - 0.26 9.2 8.8 0.32 8.9 6.1 1.0 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) RhoGEF PF00621.15 ETN99756.1 - 9.1e-27 94.0 0.0 1.2e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain CDC37_N PF03234.9 ETN99756.1 - 0.0054 17.0 1.7 0.006 16.9 0.1 1.7 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding Phage_Integr_2 PF13009.1 ETN99756.1 - 0.061 12.2 0.2 0.1 11.5 0.1 1.3 1 0 0 1 1 1 0 Putative phage integrase SpoIISA_toxin PF14171.1 ETN99756.1 - 0.29 10.3 2.9 9 5.4 0.6 2.1 2 0 0 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system Innate_immun PF12782.2 ETN99758.1 - 0.033 13.4 7.8 0.038 13.2 5.4 1.1 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family MSV199 PF10553.4 ETN99758.1 - 0.076 12.8 0.1 0.087 12.7 0.1 1.2 1 0 0 1 1 1 0 MSV199 domain GTP_EFTU_D4 PF14578.1 ETN99759.1 - 2.5e-10 39.8 0.9 4.9e-10 38.9 0.3 1.7 2 0 0 2 2 2 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.20 ETN99759.1 - 2.4e-08 33.9 0.2 4.8e-08 33.0 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU PF00009.22 ETN99759.1 - 0.00026 20.4 0.0 0.00034 20.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Nudix_N PF12535.3 ETN99759.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal Gly_rich PF12810.2 ETN99760.1 - 0.012 15.1 1.2 0.02 14.5 0.8 1.3 1 0 0 1 1 1 0 Glycine rich protein DUF4361 PF14274.1 ETN99760.1 - 0.025 14.2 0.1 0.067 12.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4361) DUF2075 PF09848.4 ETN99761.1 - 0.073 12.0 1.2 0.084 11.8 0.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) BpuSI_N PF15516.1 ETN99761.1 - 0.077 12.6 4.0 0.23 11.1 2.8 1.8 1 1 0 1 1 1 0 BpuSI N-terminal domain FERM_C PF09380.5 ETN99761.1 - 0.57 10.4 4.1 12 6.2 2.8 2.1 1 1 0 1 1 1 0 FERM C-terminal PH-like domain HAUS6_N PF14661.1 ETN99762.1 - 0.069 12.4 2.6 0.073 12.4 1.8 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Med2 PF11214.3 ETN99762.1 - 0.24 11.4 7.4 0.41 10.7 5.1 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 Cpn60_TCP1 PF00118.19 ETN99763.1 - 8.6e-10 37.8 0.2 7.1e-09 34.8 0.0 1.8 1 1 1 2 2 2 1 TCP-1/cpn60 chaperonin family Toxin_65 PF15543.1 ETN99763.1 - 0.016 14.8 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Putative toxin 65 AcylCoA_dehyd_C PF12186.3 ETN99764.1 - 0.1 12.4 0.6 0.45 10.3 0.1 1.8 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase C terminal HTH_44 PF14641.1 ETN99765.1 - 0.021 14.8 0.9 0.04 13.9 0.2 1.7 2 1 0 2 2 2 0 Helix-turn-helix DNA-binding domain of SPT6 DUF4485 PF14846.1 ETN99765.1 - 0.058 13.1 0.1 0.089 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) RPAP3_C PF13877.1 ETN99765.1 - 0.075 13.0 0.4 0.12 12.3 0.3 1.5 1 1 0 1 1 1 0 Potential Monad-binding region of RPAP3 DUF2420 PF10336.4 ETN99765.1 - 0.082 12.5 1.2 0.13 11.8 0.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2420) PMSR PF01625.16 ETN99766.1 - 0.019 14.8 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Peptide methionine sulfoxide reductase NACHT PF05729.7 ETN99767.1 - 4.9e-05 23.0 0.8 0.0007 19.2 0.3 2.5 1 1 1 2 2 2 1 NACHT domain AAA_18 PF13238.1 ETN99767.1 - 0.0077 16.5 6.7 0.0087 16.3 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 ETN99767.1 - 0.95 9.3 7.2 2 8.3 0.5 2.7 1 1 1 2 2 2 0 AAA domain IL15 PF02372.10 ETN99767.1 - 2.8 7.7 7.2 1.7 8.4 1.2 2.5 2 1 0 2 2 2 0 Interleukin 15 DUF1546 PF07571.8 ETN99768.1 - 0.015 15.3 0.0 0.14 12.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) COQ9 PF08511.6 ETN99768.1 - 0.066 12.7 0.1 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 COQ9 Ribosomal_S27 PF01599.14 ETN99768.1 - 0.19 11.5 0.2 0.19 11.5 0.2 2.6 3 0 0 3 3 3 0 Ribosomal protein S27a zf-C3HC PF07967.8 ETN99768.1 - 0.75 9.5 4.7 2.5 7.8 2.0 2.0 1 1 1 2 2 2 0 C3HC zinc finger-like 5HT_transporter PF03491.8 ETN99769.1 - 0.022 14.8 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 Serotonin (5-HT) neurotransmitter transporter, N-terminus Daxx PF03344.10 ETN99770.1 - 0.13 10.7 19.2 0.15 10.5 13.3 1.1 1 0 0 1 1 1 0 Daxx Family CRT10 PF08728.5 ETN99770.1 - 0.16 9.9 4.4 0.19 9.6 3.1 1.1 1 0 0 1 1 1 0 CRT10 DDHD PF02862.12 ETN99770.1 - 1.5 8.5 10.8 2.1 8.1 7.5 1.4 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 ETN99770.1 - 1.8 8.3 13.5 2.3 8.0 9.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FLO_LFY PF01698.11 ETN99770.1 - 2.9 6.6 10.2 3.9 6.2 7.1 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein TRAP_alpha PF03896.11 ETN99770.1 - 3.9 6.3 9.9 6.1 5.7 6.8 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Paramyxo_ncap PF00973.14 ETN99770.1 - 6.9 5.2 14.4 7.1 5.2 8.8 1.7 2 0 0 2 2 2 0 Paramyxovirus nucleocapsid protein SeqA PF03925.8 ETN99772.1 - 0.0013 18.4 1.9 0.0033 17.1 0.1 1.9 1 1 1 2 2 2 1 SeqA protein YhdB PF14148.1 ETN99772.1 - 0.13 11.9 1.3 0.48 10.2 0.1 2.1 2 0 0 2 2 2 0 YhdB-like protein Mcp5_PH PF12814.2 ETN99773.1 - 3.4e-05 23.7 0.1 4.4e-05 23.3 0.1 1.3 1 1 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Stc1 PF12898.2 ETN99774.1 - 0.043 13.8 0.0 0.059 13.4 0.0 1.3 1 0 0 1 1 1 0 Stc1 domain MotB_plug PF13677.1 ETN99774.1 - 2.4 7.5 4.9 2.7 7.3 2.3 1.8 2 0 0 2 2 2 0 Membrane MotB of proton-channel complex MotA/MotB MPC PF03650.8 ETN99775.1 - 0.0013 18.6 0.9 0.0018 18.1 0.6 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Prothymosin PF03247.9 ETN99776.1 - 0.013 15.6 17.6 0.016 15.3 12.2 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family VID27 PF08553.5 ETN99776.1 - 0.047 11.9 15.5 0.052 11.7 10.8 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein UPF0560 PF10577.4 ETN99776.1 - 0.053 11.7 1.8 0.059 11.6 1.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TRAP_alpha PF03896.11 ETN99776.1 - 0.12 11.3 8.5 0.13 11.2 5.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Mis14 PF08641.7 ETN99776.1 - 0.13 12.3 7.3 0.15 12.1 5.0 1.1 1 0 0 1 1 1 0 Kinetochore protein Mis14 like DUF2457 PF10446.4 ETN99776.1 - 0.13 10.9 15.3 0.14 10.8 10.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 ETN99776.1 - 0.15 9.9 15.7 0.15 9.9 10.9 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4375 PF14300.1 ETN99776.1 - 0.17 11.8 9.3 0.22 11.5 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) BTV_NS2 PF04514.7 ETN99776.1 - 0.2 10.5 13.0 0.22 10.3 9.0 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 NOA36 PF06524.7 ETN99776.1 - 0.21 10.8 8.5 0.23 10.6 5.9 1.1 1 0 0 1 1 1 0 NOA36 protein CobT PF06213.7 ETN99776.1 - 0.28 10.2 11.3 0.31 10.1 7.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PI3K_1B_p101 PF10486.4 ETN99776.1 - 0.35 8.4 5.6 0.35 8.3 3.8 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Daxx PF03344.10 ETN99776.1 - 0.37 9.2 13.2 0.37 9.2 9.1 1.0 1 0 0 1 1 1 0 Daxx Family Trypan_PARP PF05887.6 ETN99776.1 - 0.38 10.5 6.3 0.43 10.3 4.3 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pox_Ag35 PF03286.9 ETN99776.1 - 0.7 9.3 13.2 0.82 9.1 9.1 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Myc_N PF01056.13 ETN99776.1 - 1 8.4 7.5 1.1 8.3 5.2 1.2 1 0 0 1 1 1 0 Myc amino-terminal region CDC45 PF02724.9 ETN99776.1 - 1.2 7.0 13.1 1.3 6.9 9.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Tom22 PF04281.8 ETN99776.1 - 1.4 8.4 7.4 1.7 8.1 5.1 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 YqfQ PF14181.1 ETN99776.1 - 1.5 8.8 10.2 1.9 8.4 7.0 1.2 1 0 0 1 1 1 0 YqfQ-like protein DNA_pol_phi PF04931.8 ETN99776.1 - 1.7 6.3 18.5 1.9 6.1 12.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sporozoite_P67 PF05642.6 ETN99776.1 - 3 5.6 9.0 3.1 5.5 6.2 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1510 PF07423.6 ETN99776.1 - 3.1 7.1 15.2 3.3 7.0 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Dicty_REP PF05086.7 ETN99776.1 - 3.5 5.2 14.9 4.2 5.0 10.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AAA_11 PF13086.1 ETN99776.1 - 4 6.9 7.4 4.3 6.8 5.1 1.0 1 0 0 1 1 1 0 AAA domain RNA_pol_3_Rpc31 PF11705.3 ETN99776.1 - 6 6.7 19.4 7.8 6.3 13.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SID-1_RNA_chan PF13965.1 ETN99776.1 - 7.3 4.6 7.0 8.3 4.4 4.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PUB PF09409.5 ETN99777.1 - 0.0021 17.8 0.2 0.011 15.4 0.1 2.0 1 1 0 1 1 1 1 PUB domain DUF4449 PF14613.1 ETN99778.1 - 0.14 12.1 6.0 0.19 11.6 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) ECIST_Cterm PF14784.1 ETN99778.1 - 0.17 11.8 3.8 0.24 11.3 2.7 1.2 1 0 0 1 1 1 0 C-terminal domain of the ECSIT protein AAA_23 PF13476.1 ETN99778.1 - 0.23 11.7 10.9 0.3 11.3 7.6 1.1 1 0 0 1 1 1 0 AAA domain Spore_III_AF PF09581.5 ETN99778.1 - 0.29 10.9 6.0 0.36 10.6 4.2 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Phage_GPO PF05929.6 ETN99778.1 - 0.39 9.9 4.9 0.5 9.5 3.4 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase APG6 PF04111.7 ETN99778.1 - 0.58 9.1 10.2 0.81 8.6 7.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 AIF_C PF14721.1 ETN99778.1 - 0.75 10.0 3.6 1.1 9.5 2.5 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term OmpH PF03938.9 ETN99778.1 - 2.4 8.0 13.1 3.2 7.6 9.1 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4094 PF13334.1 ETN99778.1 - 7.7 6.9 7.6 19 5.7 5.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Membralin PF09746.4 ETN99780.1 - 0.11 11.5 2.8 0.1 11.6 2.0 1.0 1 0 0 1 1 1 0 Tumour-associated protein FlaF PF07309.6 ETN99780.1 - 0.25 11.1 3.4 0.27 11.0 2.0 1.3 1 1 0 1 1 1 0 Flagellar protein FlaF Latarcin PF10279.4 ETN99780.1 - 0.29 11.3 5.3 0.4 10.9 3.7 1.3 1 1 0 1 1 1 0 Latarcin precursor Hemocyanin_N PF03722.9 ETN99783.1 - 0.052 13.7 6.9 0.073 13.2 2.9 2.3 1 1 1 2 2 2 0 Hemocyanin, all-alpha domain Folate_carrier PF01770.13 ETN99784.1 - 0.062 11.8 4.2 0.074 11.5 2.9 1.0 1 0 0 1 1 1 0 Reduced folate carrier PsiA PF06952.6 ETN99784.1 - 0.42 9.6 8.4 0.26 10.3 4.7 1.4 1 1 1 2 2 2 0 PsiA protein CDC45 PF02724.9 ETN99784.1 - 0.9 7.4 12.6 0.97 7.3 8.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2413 PF10310.4 ETN99784.1 - 2.7 6.7 12.3 2.5 6.7 8.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DDHD PF02862.12 ETN99784.1 - 6.8 6.4 8.8 7.1 6.3 6.1 1.2 1 0 0 1 1 1 0 DDHD domain SMN PF06003.7 ETN99784.1 - 8.5 5.3 13.7 9.7 5.1 9.5 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) TPR_12 PF13424.1 ETN99785.1 - 0.0011 18.8 0.3 0.0021 17.9 0.1 1.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETN99785.1 - 0.01 15.4 2.0 0.031 13.9 1.4 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETN99785.1 - 0.018 14.9 1.2 0.062 13.2 0.8 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 ETN99785.1 - 0.028 14.0 0.2 0.063 12.9 0.1 1.7 1 1 0 1 1 1 0 TPR repeat TPR_8 PF13181.1 ETN99785.1 - 0.25 11.2 4.8 0.78 9.6 3.3 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat BicD PF09730.4 ETN99788.1 - 0.00011 20.7 6.0 0.00013 20.5 4.2 1.2 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D SprA-related PF12118.3 ETN99788.1 - 0.034 13.4 13.1 0.042 13.1 9.1 1.0 1 0 0 1 1 1 0 SprA-related family COG5 PF10392.4 ETN99788.1 - 0.089 12.7 4.7 0.14 12.1 3.3 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF1664 PF07889.7 ETN99788.1 - 0.19 11.5 3.6 0.25 11.1 2.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) LicD PF04991.8 ETN99788.1 - 0.58 10.2 8.9 0.16 12.0 4.4 1.5 1 1 0 1 1 1 0 LicD family Mnd1 PF03962.10 ETN99788.1 - 0.77 9.3 10.9 1.2 8.7 7.5 1.4 1 1 0 1 1 1 0 Mnd1 family DAP PF15228.1 ETN99789.1 - 0.66 10.7 2.7 0.74 10.5 0.2 2.2 2 0 0 2 2 2 0 Death-associated protein Tat PF00539.13 ETN99791.1 - 0.35 10.5 0.1 0.35 10.5 0.1 1.9 2 0 0 2 2 2 0 Transactivating regulatory protein (Tat) Erythro-docking PF09277.6 ETN99793.1 - 3.7 7.3 6.4 2.8 7.7 0.7 2.3 1 1 1 2 2 2 0 Erythronolide synthase, docking DUF3714 PF12508.3 ETN99794.1 - 0.019 14.4 0.0 0.021 14.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3714) NAF PF03822.9 ETN99794.1 - 0.023 14.4 0.9 0.042 13.5 0.6 1.4 1 0 0 1 1 1 0 NAF domain WD40 PF00400.27 ETN99795.1 - 0.00079 19.2 0.3 0.0012 18.6 0.2 1.3 1 0 0 1 1 1 1 WD domain, G-beta repeat Vfa1 PF08432.5 ETN99795.1 - 0.0076 16.2 4.2 0.0088 16.0 2.9 1.1 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Peptidase_M43 PF05572.8 ETN99795.1 - 0.036 13.6 1.8 0.062 12.9 1.2 1.6 1 1 0 1 1 1 0 Pregnancy-associated plasma protein-A LppC PF04348.8 ETN99795.1 - 0.043 12.3 1.0 0.05 12.1 0.7 1.1 1 0 0 1 1 1 0 LppC putative lipoprotein Gag_p17 PF00540.13 ETN99795.1 - 0.13 12.0 1.9 0.16 11.6 1.3 1.1 1 0 0 1 1 1 0 gag gene protein p17 (matrix protein) Hom_end_hint PF05203.11 ETN99795.1 - 0.16 11.7 3.3 0.17 11.6 2.3 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint CDV3 PF15359.1 ETN99795.1 - 0.71 9.9 6.2 0.96 9.5 4.3 1.2 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 FRG2 PF15315.1 ETN99797.1 - 1.3 8.9 20.2 2.6 7.9 2.3 2.2 1 1 1 2 2 2 0 Facioscapulohumeral muscular dystrophy candidate 2 DUF4551 PF15087.1 ETN99797.1 - 3.5 5.8 12.3 3.5 5.8 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Gag_spuma PF03276.9 ETN99797.1 - 8.5 4.5 20.0 10 4.2 13.8 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Tankyrase_bdg_C PF15327.1 ETN99798.1 - 0.11 12.6 1.3 0.13 12.4 0.9 1.0 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain AAA_18 PF13238.1 ETN99799.1 - 1.3e-05 25.5 0.0 1.4e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ETN99799.1 - 0.00025 21.1 0.0 0.00027 21.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 ETN99799.1 - 0.00035 20.2 0.0 0.00037 20.1 0.0 1.2 1 1 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 ETN99799.1 - 0.00046 20.9 0.0 0.0005 20.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 ETN99799.1 - 0.0019 17.8 0.0 0.002 17.7 0.0 1.2 1 1 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 ETN99799.1 - 0.0021 17.9 0.0 0.0023 17.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 ETN99799.1 - 0.0069 16.5 0.2 0.015 15.4 0.1 1.7 1 1 0 1 1 1 1 RNA helicase VirE PF05272.6 ETN99799.1 - 0.0098 15.3 0.1 0.011 15.1 0.1 1.3 1 1 0 1 1 1 1 Virulence-associated protein E ATP_bind_2 PF03668.10 ETN99799.1 - 0.014 14.4 0.0 0.014 14.4 0.0 1.1 1 0 0 1 1 1 0 P-loop ATPase protein family ABC_tran PF00005.22 ETN99799.1 - 0.025 14.8 0.5 0.029 14.6 0.3 1.3 1 1 0 1 1 1 0 ABC transporter DUF2075 PF09848.4 ETN99799.1 - 0.042 12.8 0.0 0.046 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PduV-EutP PF10662.4 ETN99799.1 - 0.049 13.1 0.1 0.082 12.3 0.1 1.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 ETN99799.1 - 0.05 13.3 0.0 0.06 13.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) PRK PF00485.13 ETN99799.1 - 0.057 12.9 0.0 0.058 12.9 0.0 1.1 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.1 ETN99799.1 - 0.062 13.2 0.0 0.062 13.2 0.0 1.2 1 1 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 ETN99799.1 - 0.063 12.4 0.1 0.11 11.6 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 KaiC PF06745.8 ETN99799.1 - 0.071 12.2 0.1 0.082 12.0 0.1 1.5 1 1 0 1 1 1 0 KaiC AAA_29 PF13555.1 ETN99799.1 - 0.079 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.1 ETN99799.1 - 0.091 12.3 0.0 0.091 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain CPT PF07931.7 ETN99799.1 - 0.1 12.2 0.0 0.1 12.1 0.0 1.2 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Sigma54_activat PF00158.21 ETN99799.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.4 2 0 0 2 2 2 0 Sigma-54 interaction domain SCF PF02404.10 ETN99800.1 - 0.043 13.0 0.3 0.051 12.7 0.2 1.1 1 0 0 1 1 1 0 Stem cell factor Not3 PF04065.10 ETN99801.1 - 3.1e-42 144.4 18.4 3.3e-42 144.3 12.8 1.0 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component DUF3508 PF12018.3 ETN99801.1 - 0.018 14.0 3.8 0.023 13.7 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3508) Mnd1 PF03962.10 ETN99801.1 - 0.27 10.8 10.8 0.38 10.3 7.5 1.3 1 0 0 1 1 1 0 Mnd1 family DUF342 PF03961.8 ETN99801.1 - 0.29 9.4 8.6 0.33 9.3 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) NOP5NT PF08156.8 ETN99801.1 - 2.1 8.5 5.3 8 6.7 0.7 2.9 2 1 1 3 3 3 0 NOP5NT (NUC127) domain Toxin_65 PF15543.1 ETN99805.1 - 0.074 12.6 0.1 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative toxin 65 Sprouty PF05210.8 ETN99805.1 - 0.081 12.9 0.2 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 Sprouty protein (Spry) G-alpha PF00503.15 ETN99806.1 - 8.8e-12 44.3 0.0 1.5e-11 43.6 0.0 1.4 1 1 0 1 1 1 1 G-protein alpha subunit zf-RING_2 PF13639.1 ETN99807.1 - 0.0073 16.1 3.3 0.018 14.8 2.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETN99807.1 - 0.011 15.7 4.7 0.13 12.2 3.2 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.9 ETN99807.1 - 0.072 12.5 3.9 2.4 7.7 0.9 2.4 2 0 0 2 2 2 0 P-11 zinc finger zf-MIZ PF02891.15 ETN99807.1 - 1.6 8.3 7.5 0.27 10.7 1.7 2.3 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger RGS PF00615.14 ETN99808.1 - 0.00065 19.7 0.7 0.00076 19.5 0.0 1.4 2 0 0 2 2 2 1 Regulator of G protein signaling domain DUF4441 PF14536.1 ETN99808.1 - 0.034 14.1 1.4 0.035 14.0 0.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4441) CYSTM PF12734.2 ETN99808.1 - 0.13 12.3 0.1 0.35 10.9 0.1 1.7 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance RNase_H2-Ydr279 PF09468.5 ETN99808.1 - 6 5.9 7.5 8 5.5 5.2 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) WD40 PF00400.27 ETN99809.1 - 1.6e-24 84.8 6.8 1.1e-07 31.4 0.0 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat Vhr1 PF04001.8 ETN99809.1 - 0.028 14.3 0.1 0.059 13.2 0.1 1.5 1 0 0 1 1 1 0 Transcription factor Vhr1 CENP-T PF15511.1 ETN99810.1 - 0.035 13.3 7.7 0.038 13.2 5.4 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Cytadhesin_P30 PF07271.6 ETN99810.1 - 0.12 11.5 1.6 0.13 11.4 1.1 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 Daxx PF03344.10 ETN99810.1 - 0.73 8.2 16.7 0.74 8.2 11.6 1.0 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 ETN99810.1 - 1.5 7.4 22.9 1.6 7.3 15.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Trypan_PARP PF05887.6 ETN99810.1 - 1.5 8.6 6.4 1.6 8.5 4.4 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) YL1 PF05764.8 ETN99810.1 - 1.8 8.1 10.5 1.9 8.0 7.3 1.0 1 0 0 1 1 1 0 YL1 nuclear protein Hid1 PF12722.2 ETN99810.1 - 2.7 5.5 11.5 2.7 5.5 8.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.9 ETN99810.1 - 4.3 5.2 12.6 4 5.3 8.7 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 ETN99810.1 - 5.1 6.4 13.8 5.4 6.3 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) BUD22 PF09073.5 ETN99810.1 - 6.6 5.6 14.9 6.8 5.6 10.3 1.0 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.7 ETN99810.1 - 7.2 5.7 15.6 7.6 5.7 10.8 1.1 1 0 0 1 1 1 0 SDA1 AAA_5 PF07728.9 ETN99813.1 - 9.3e-29 99.9 0.0 1.1e-16 60.8 0.0 3.6 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 ETN99813.1 - 1.1e-14 54.1 0.0 1.4e-11 44.0 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 ETN99813.1 - 9.3e-10 38.8 0.0 0.00025 21.2 0.0 3.6 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETN99813.1 - 3.1e-07 30.6 0.0 0.048 13.8 0.0 3.8 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 ETN99813.1 - 1.6e-06 28.2 5.3 0.01 15.8 0.0 4.1 4 1 0 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 ETN99813.1 - 4.9e-06 27.3 0.3 0.027 15.3 0.1 3.7 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.1 ETN99813.1 - 3.3e-05 24.1 0.0 0.0099 16.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 ETN99813.1 - 7.1e-05 22.7 0.0 0.11 12.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 ETN99813.1 - 0.00033 19.8 0.0 0.0047 16.0 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_14 PF13173.1 ETN99813.1 - 0.00034 20.5 0.0 0.12 12.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 ETN99813.1 - 0.00093 19.1 2.3 0.37 10.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 ETN99813.1 - 0.0015 17.9 0.0 0.036 13.4 0.0 2.8 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF258 PF03193.11 ETN99813.1 - 0.002 17.3 0.0 0.24 10.5 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 ETN99813.1 - 0.002 18.4 0.5 2.1 8.6 0.0 3.2 3 0 0 3 3 3 1 ABC transporter Mg_chelatase PF01078.16 ETN99813.1 - 0.0041 16.3 0.0 4.9 6.2 0.0 3.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Miro PF08477.8 ETN99813.1 - 0.0047 17.4 0.0 2.7 8.5 0.0 3.0 2 1 0 2 2 2 1 Miro-like protein DUF815 PF05673.8 ETN99813.1 - 0.0048 15.8 0.0 0.26 10.1 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 ETN99813.1 - 0.0057 16.3 0.0 0.32 10.7 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain Sigma54_activ_2 PF14532.1 ETN99813.1 - 0.0069 16.4 0.0 2.1 8.3 0.0 3.0 2 0 0 2 2 2 1 Sigma-54 interaction domain Arch_ATPase PF01637.13 ETN99813.1 - 0.0074 16.0 0.0 0.34 10.5 0.0 2.5 2 0 0 2 2 2 1 Archaeal ATPase MobB PF03205.9 ETN99813.1 - 0.0081 15.8 0.0 4.2 7.0 0.0 3.6 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_6 PF12774.2 ETN99813.1 - 0.0082 15.7 0.0 3 7.2 0.0 3.0 2 1 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 Rad17 PF03215.10 ETN99813.1 - 0.011 14.5 0.0 0.15 10.6 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein T2SE PF00437.15 ETN99813.1 - 0.014 14.2 0.0 2.1 7.1 0.0 2.7 2 0 0 2 2 2 0 Type II/IV secretion system protein RNA_helicase PF00910.17 ETN99813.1 - 0.016 15.3 0.0 11 6.2 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.1 ETN99813.1 - 0.02 14.4 1.6 3.1 7.3 0.0 3.5 4 0 0 4 4 3 0 AAA domain Sigma54_activat PF00158.21 ETN99813.1 - 0.021 14.3 0.0 4.2 6.8 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_29 PF13555.1 ETN99813.1 - 0.034 13.6 0.0 1.5 8.4 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 ETN99813.1 - 0.038 13.9 0.0 5.3 7.0 0.0 3.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase PduV-EutP PF10662.4 ETN99813.1 - 0.097 12.1 0.0 5.4 6.5 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF3895 PF13034.1 ETN99814.1 - 0.0021 17.4 0.5 1.8 8.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3895) Gon7 PF08738.5 ETN99815.1 - 0.19 11.7 3.1 0.87 9.6 1.0 2.2 2 0 0 2 2 2 0 Gon7 family DUF4530 PF15039.1 ETN99815.1 - 0.26 11.2 5.2 0.4 10.6 3.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) Baculo_RING PF05883.6 ETN99816.1 - 0.058 13.2 0.2 0.1 12.4 0.2 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain Dynamin_N PF00350.18 ETN99816.1 - 0.19 11.5 1.9 0.91 9.3 0.0 2.1 1 1 0 2 2 2 0 Dynamin family zf-TRAF PF02176.13 ETN99817.1 - 7.3e-06 26.2 7.1 2.7e-05 24.4 4.9 2.0 1 0 0 1 1 1 1 TRAF-type zinc finger zf-MIZ PF02891.15 ETN99818.1 - 0.11 12.0 1.2 0.41 10.1 0.9 2.0 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C3HC4_2 PF13923.1 ETN99818.1 - 0.14 12.1 3.0 1.2 9.2 1.1 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-H2C2_5 PF13909.1 ETN99820.1 - 0.23 11.7 1.7 0.34 11.2 0.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-TRAF PF02176.13 ETN99820.1 - 2.3 8.6 5.6 8 6.9 0.1 2.6 2 1 0 2 2 2 0 TRAF-type zinc finger RUN PF02759.14 ETN99822.1 - 0.086 12.5 1.3 1.9 8.2 0.1 2.2 1 1 1 2 2 2 0 RUN domain P16-Arc PF04699.9 ETN99822.1 - 0.1 12.6 0.6 0.12 12.4 0.4 1.1 1 0 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) Pox_D5 PF03288.11 ETN99823.1 - 1.2 9.4 4.4 0.27 11.5 0.7 1.8 2 1 0 2 2 2 0 Poxvirus D5 protein-like DUF4485 PF14846.1 ETN99824.1 - 0.063 13.0 0.3 0.11 12.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) ubiquitin PF00240.18 ETN99825.1 - 9.5e-22 76.1 1.2 1.3e-13 50.1 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 ETN99825.1 - 1.2e-11 44.0 0.8 5.9e-07 29.0 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 ETN99825.1 - 0.032 14.4 0.2 0.41 10.9 0.1 2.7 2 1 0 2 2 2 0 Ubiquitin-like domain HEAT_2 PF13646.1 ETN99827.1 - 1.6e-09 37.9 0.0 1.4e-06 28.4 0.0 2.9 2 1 0 2 2 2 2 HEAT repeats HEAT PF02985.17 ETN99827.1 - 1.6e-09 37.0 0.0 0.059 13.4 0.0 4.6 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.1 ETN99827.1 - 2.9e-05 24.4 0.0 0.09 13.2 0.0 3.9 2 1 2 4 4 4 2 HEAT-like repeat Cnd1 PF12717.2 ETN99827.1 - 0.006 16.4 10.7 0.32 10.8 1.9 2.8 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 PPR_2 PF13041.1 ETN99828.1 - 0.0021 18.0 0.0 0.0047 16.8 0.0 1.6 1 0 0 1 1 1 1 PPR repeat family PPR PF01535.15 ETN99828.1 - 0.0088 15.9 0.2 0.024 14.6 0.0 1.8 2 0 0 2 2 2 1 PPR repeat WHEP-TRS PF00458.15 ETN99828.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 WHEP-TRS domain DUF1900 PF08954.6 ETN99828.1 - 0.11 11.9 0.2 1.8 8.0 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1900) zf-TRAF PF02176.13 ETN99829.1 - 3e-05 24.3 7.8 7.2e-05 23.0 5.4 1.7 1 1 0 1 1 1 1 TRAF-type zinc finger Atg14 PF10186.4 ETN99829.1 - 0.008 15.1 3.0 0.0096 14.8 2.1 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 CCDC144C PF14915.1 ETN99829.1 - 0.013 14.4 6.0 0.033 13.0 4.2 1.7 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region Shugoshin_N PF07558.6 ETN99829.1 - 0.016 14.9 2.8 1.5 8.6 0.0 2.6 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF342 PF03961.8 ETN99829.1 - 0.022 13.2 2.6 0.029 12.8 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4047 PF13256.1 ETN99829.1 - 0.022 14.7 1.7 0.12 12.2 1.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) FliJ PF02050.11 ETN99829.1 - 0.032 14.2 5.5 0.032 14.2 3.8 1.6 2 0 0 2 2 2 0 Flagellar FliJ protein DUF2205 PF10224.4 ETN99829.1 - 0.061 12.8 4.1 0.26 10.8 0.4 2.4 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF3837 PF12939.2 ETN99829.1 - 0.068 13.1 0.8 0.12 12.3 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3837) TSC22 PF01166.13 ETN99829.1 - 0.089 12.7 5.4 0.35 10.8 1.9 2.5 1 1 0 2 2 2 0 TSC-22/dip/bun family ATG16 PF08614.6 ETN99829.1 - 0.096 12.5 5.5 0.19 11.5 3.8 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Herpes_BLRF2 PF05812.7 ETN99829.1 - 0.098 12.4 3.7 0.16 11.7 2.6 1.4 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein DUF972 PF06156.8 ETN99829.1 - 0.28 11.5 10.2 0.03 14.6 3.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Rabaptin PF03528.10 ETN99829.1 - 0.99 9.3 8.4 0.069 13.0 2.3 1.6 2 0 0 2 2 2 0 Rabaptin MOR2-PAG1_N PF14222.1 ETN99830.1 - 0.0015 17.3 0.1 0.004 15.9 0.1 1.8 2 0 0 2 2 2 1 Cell morphogenesis N-terminal TIP120 PF08623.5 ETN99830.1 - 0.0093 15.5 0.3 1.5 8.4 0.0 2.4 2 0 0 2 2 2 2 TATA-binding protein interacting (TIP20) PBS_linker_poly PF00427.16 ETN99830.1 - 0.13 11.9 0.0 0.32 10.6 0.0 1.6 2 0 0 2 2 2 0 Phycobilisome Linker polypeptide Kelch_1 PF01344.20 ETN99831.1 - 9e-08 31.5 0.9 5.6e-06 25.8 0.4 2.3 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.1 ETN99831.1 - 2.3e-07 30.4 0.4 0.001 18.7 0.1 2.2 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETN99831.1 - 5e-06 26.0 0.6 0.035 13.8 0.2 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.1 ETN99831.1 - 5.3e-06 26.3 0.5 0.00018 21.5 0.1 2.2 1 1 1 2 2 2 1 Kelch motif Kelch_5 PF13854.1 ETN99831.1 - 0.0012 18.7 0.7 0.0089 15.9 0.3 2.1 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETN99831.1 - 0.0031 17.6 0.0 0.008 16.3 0.0 1.7 2 0 0 2 2 2 1 Galactose oxidase, central domain Spore_YhaL PF14147.1 ETN99831.1 - 0.094 12.1 6.4 0.18 11.2 3.7 2.0 2 0 0 2 2 2 0 Sporulation protein YhaL Peptidase_M1 PF01433.15 ETN99832.1 - 1.4e-20 73.7 4.0 2.9e-10 39.8 0.1 3.0 1 1 2 3 3 3 3 Peptidase family M1 TPR_12 PF13424.1 ETN99833.1 - 3.9e-45 151.6 10.2 3.9e-23 81.1 0.1 2.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETN99833.1 - 9.8e-25 85.0 15.3 2.9e-10 39.2 0.9 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETN99833.1 - 3.8e-24 83.8 0.0 3.3e-08 33.2 0.0 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETN99833.1 - 6.9e-20 69.3 8.6 3.2e-07 29.7 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETN99833.1 - 3.9e-19 68.0 8.4 6.3e-11 41.7 3.8 2.5 2 1 0 2 2 2 2 TPR repeat TPR_8 PF13181.1 ETN99833.1 - 2.2e-18 64.5 19.1 4e-08 32.4 0.4 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETN99833.1 - 8.4e-17 59.5 0.6 4.9e-06 25.9 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat SNAP PF14938.1 ETN99833.1 - 3.1e-08 33.1 1.9 3.5e-08 32.9 1.3 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.1 ETN99833.1 - 7.1e-08 32.4 1.0 0.16 12.5 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETN99833.1 - 2.4e-07 30.3 10.3 0.01 15.9 0.1 4.2 3 2 0 3 3 3 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETN99833.1 - 1.9e-06 26.9 1.5 0.16 11.2 0.0 3.4 3 0 0 3 3 3 2 SHNi-TPR MIT PF04212.13 ETN99833.1 - 4.8e-06 26.3 9.7 0.11 12.4 0.1 3.1 3 0 0 3 3 3 3 MIT (microtubule interacting and transport) domain TPR_14 PF13428.1 ETN99833.1 - 5.6e-06 26.5 0.0 0.77 10.5 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETN99833.1 - 1.4e-05 25.5 0.0 0.0034 18.0 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 ETN99833.1 - 0.00041 20.4 5.9 0.011 15.8 1.0 2.6 1 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF2225 PF09986.4 ETN99833.1 - 0.00052 19.5 7.6 0.00081 18.9 5.2 1.3 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) PPR PF01535.15 ETN99833.1 - 0.0013 18.5 0.4 4.1 7.5 0.0 3.3 3 0 0 3 3 3 1 PPR repeat TPR_3 PF07720.7 ETN99833.1 - 0.0018 18.0 7.7 0.056 13.2 0.2 3.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETN99833.1 - 0.012 15.8 0.1 1.9 8.8 0.0 2.5 1 1 0 2 2 2 0 Tetratricopeptide repeat Toxin_13 PF07822.6 ETN99833.1 - 0.073 12.9 1.7 3.3 7.6 0.2 2.4 2 0 0 2 2 2 0 Neurotoxin B-IV-like protein NSF PF02071.15 ETN99833.1 - 0.22 12.1 6.3 74 4.6 0.0 3.6 3 0 0 3 3 3 0 Aromatic-di-Alanine (AdAR) repeat DUF4071 PF13281.1 ETN99833.1 - 0.25 10.1 4.8 0.89 8.3 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4071) DUF2262 PF10020.4 ETN99833.1 - 0.29 11.3 5.5 0.84 9.8 3.8 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2262) Jnk-SapK_ap_N PF09744.4 ETN99833.1 - 0.78 9.7 9.9 1.6 8.6 2.0 2.5 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 BSP_II PF05432.6 ETN99834.1 - 4 6.6 8.3 4.7 6.4 5.8 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) WD40 PF00400.27 ETN99835.1 - 3.3e-22 77.5 0.5 3e-11 42.7 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Pentapeptide_4 PF13599.1 ETN99835.1 - 8e-07 28.7 0.2 2.2e-06 27.3 0.1 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 ETN99835.1 - 4.1e-05 23.3 0.8 0.00011 22.0 0.5 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETN99835.1 - 6.5e-05 22.0 5.7 0.00016 20.8 3.6 1.9 1 1 0 1 1 1 1 Pentapeptide repeats (8 copies) PD40 PF07676.7 ETN99835.1 - 0.0019 17.7 0.4 1.9 8.2 0.0 2.9 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Omptin PF01278.15 ETN99835.1 - 0.027 13.5 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Omptin family SEO_N PF14576.1 ETN99836.1 - 0.0013 18.0 3.1 0.0013 18.0 2.1 1.7 1 1 0 1 1 1 1 Sieve element occlusion N-terminus AAA-ATPase_like PF09820.4 ETN99836.1 - 0.037 13.1 4.4 0.047 12.8 3.1 1.2 1 0 0 1 1 1 0 Predicted AAA-ATPase GvpO PF05800.6 ETN99836.1 - 0.038 13.8 2.9 0.13 12.1 0.1 2.2 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpO DHC PF09626.5 ETN99836.1 - 0.052 14.2 1.2 0.052 14.2 0.8 1.7 2 0 0 2 2 2 0 Dihaem cytochrome c KAP_NTPase PF07693.9 ETN99836.1 - 0.055 12.4 4.5 0.051 12.5 1.1 2.1 1 1 1 2 2 2 0 KAP family P-loop domain RPAP1_N PF08621.5 ETN99836.1 - 0.072 12.6 0.2 0.072 12.6 0.1 3.5 4 1 0 4 4 4 0 RPAP1-like, N-terminal TBPIP PF07106.8 ETN99836.1 - 0.11 12.0 12.8 0.19 11.2 8.9 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Bul1_C PF04426.7 ETN99836.1 - 0.11 11.6 4.5 0.13 11.4 3.1 1.2 1 0 0 1 1 1 0 Bul1 C terminus Vir_act_alpha_C PF10400.4 ETN99836.1 - 0.4 11.0 3.6 3.8 7.9 0.3 2.6 2 1 0 2 2 2 0 Virulence activator alpha C-term Topoisom_I_N PF02919.10 ETN99836.1 - 0.77 9.0 6.8 1.1 8.5 4.7 1.3 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment DRY_EERY PF09750.4 ETN99836.1 - 1.4 9.0 7.4 2.8 8.0 5.1 1.5 1 0 0 1 1 1 0 Alternative splicing regulator Peptidase_S49_N PF08496.5 ETN99836.1 - 6.8 6.4 8.9 11 5.8 6.2 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal BRICHOS PF04089.9 ETN99836.1 - 7.4 6.5 6.2 4.3 7.2 2.4 1.9 2 0 0 2 2 2 0 BRICHOS domain RNase_HII PF01351.13 ETN99836.1 - 8.6 5.9 8.6 13 5.3 5.6 1.6 1 1 1 2 2 2 0 Ribonuclease HII DUF1102 PF06510.6 ETN99838.1 - 0.077 12.8 0.0 0.093 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1102) YaaC PF14175.1 ETN99840.1 - 2.3 7.0 7.5 0.39 9.6 2.1 1.8 1 1 1 2 2 2 0 YaaC-like Protein Pox_Ag35 PF03286.9 ETN99841.1 - 0.00011 21.7 14.1 0.00014 21.5 9.8 1.1 1 0 0 1 1 1 1 Pox virus Ag35 surface protein CDC45 PF02724.9 ETN99841.1 - 0.00024 19.3 12.0 0.00024 19.3 8.3 1.0 1 0 0 1 1 1 1 CDC45-like protein DUF3245 PF11595.3 ETN99841.1 - 0.00026 21.2 9.9 0.00031 21.0 6.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3245) RNA_pol_3_Rpc31 PF11705.3 ETN99841.1 - 0.00097 19.1 20.8 0.0012 18.8 14.4 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 DUF2457 PF10446.4 ETN99841.1 - 0.0016 17.2 25.1 0.0018 17.0 17.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) DDHD PF02862.12 ETN99841.1 - 0.0037 17.0 1.9 0.0037 17.0 1.3 1.2 1 0 0 1 1 1 1 DDHD domain DUF1510 PF07423.6 ETN99841.1 - 0.0058 16.0 19.6 0.0067 15.8 13.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) FYDLN_acid PF09538.5 ETN99841.1 - 0.011 16.2 20.1 0.014 16.0 13.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Paf1 PF03985.8 ETN99841.1 - 0.027 13.2 24.7 0.032 12.9 17.1 1.0 1 0 0 1 1 1 0 Paf1 RNA_polI_A34 PF08208.6 ETN99841.1 - 0.041 13.5 11.4 0.048 13.3 7.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 BTV_NS2 PF04514.7 ETN99841.1 - 0.061 12.2 13.3 0.07 11.9 9.2 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Daxx PF03344.10 ETN99841.1 - 0.071 11.6 28.3 0.086 11.3 19.6 1.0 1 0 0 1 1 1 0 Daxx Family RP-C_C PF11800.3 ETN99841.1 - 0.088 12.4 5.0 0.092 12.4 3.4 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region VAD1-2 PF15310.1 ETN99841.1 - 0.094 12.3 3.6 0.1 12.2 2.5 1.1 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling Zip PF02535.17 ETN99841.1 - 0.098 11.6 3.1 0.1 11.5 2.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter TLP-20 PF06088.6 ETN99841.1 - 0.1 12.2 7.9 0.14 11.7 5.5 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Tim54 PF11711.3 ETN99841.1 - 0.1 11.1 10.2 0.13 10.8 7.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Drc1-Sld2 PF11719.3 ETN99841.1 - 0.15 11.1 14.1 0.18 10.8 9.8 1.0 1 0 0 1 1 1 0 DNA replication and checkpoint protein HAUS6_N PF14661.1 ETN99841.1 - 0.2 11.0 4.1 0.2 10.9 2.8 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF913 PF06025.7 ETN99841.1 - 0.2 10.3 4.3 0.22 10.2 3.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Ycf1 PF05758.7 ETN99841.1 - 0.24 9.0 13.5 0.26 8.9 9.4 1.0 1 0 0 1 1 1 0 Ycf1 RR_TM4-6 PF06459.7 ETN99841.1 - 0.28 11.0 14.0 0.37 10.6 9.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.10 ETN99841.1 - 0.3 9.6 10.5 0.35 9.4 7.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF3449 PF11931.3 ETN99841.1 - 0.3 10.5 12.4 0.37 10.2 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) CDC27 PF09507.5 ETN99841.1 - 0.38 9.9 20.2 0.46 9.6 14.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 FLO_LFY PF01698.11 ETN99841.1 - 0.46 9.2 10.5 0.51 9.1 7.3 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein NARP1 PF12569.3 ETN99841.1 - 0.47 9.1 16.9 0.55 8.9 11.7 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SprA-related PF12118.3 ETN99841.1 - 0.53 9.5 13.9 0.61 9.3 9.6 1.0 1 0 0 1 1 1 0 SprA-related family BUD22 PF09073.5 ETN99841.1 - 0.54 9.2 25.3 0.65 9.0 17.5 1.0 1 0 0 1 1 1 0 BUD22 F-protein PF00469.15 ETN99841.1 - 0.56 9.5 10.0 0.66 9.3 6.9 1.0 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Nop25 PF09805.4 ETN99841.1 - 0.64 10.0 24.1 0.83 9.7 16.7 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF4246 PF14033.1 ETN99841.1 - 0.72 8.3 8.0 0.81 8.2 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) FGF-BP1 PF06473.7 ETN99841.1 - 0.75 9.3 6.5 0.86 9.1 4.5 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) DUF2413 PF10310.4 ETN99841.1 - 0.79 8.4 14.6 0.94 8.2 10.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Prog_receptor PF02161.10 ETN99841.1 - 0.9 8.2 7.8 0.93 8.2 5.4 1.2 1 0 0 1 1 1 0 Progesterone receptor Vfa1 PF08432.5 ETN99841.1 - 0.99 9.3 20.8 1.2 9.1 14.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FAM60A PF15396.1 ETN99841.1 - 1 9.0 5.6 1.2 8.7 3.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A CobT PF06213.7 ETN99841.1 - 1.1 8.3 24.7 1.3 8.1 17.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Cwf_Cwc_15 PF04889.7 ETN99841.1 - 1.2 8.7 23.8 1.5 8.4 16.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Astro_capsid PF03115.9 ETN99841.1 - 1.3 7.1 10.5 1.4 7.0 7.3 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Caldesmon PF02029.10 ETN99841.1 - 1.4 7.2 26.7 1.6 7.0 18.5 1.1 1 0 0 1 1 1 0 Caldesmon AIF_C PF14721.1 ETN99841.1 - 1.5 9.1 8.4 1.9 8.7 5.8 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term NOA36 PF06524.7 ETN99841.1 - 1.5 8.0 16.8 2.2 7.4 11.6 1.3 1 0 0 1 1 1 0 NOA36 protein CKAP2_C PF15297.1 ETN99841.1 - 1.5 7.5 13.9 1.8 7.2 9.7 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Nop14 PF04147.7 ETN99841.1 - 1.6 6.5 30.1 1.8 6.4 20.9 1.0 1 0 0 1 1 1 0 Nop14-like family Fmp27_WPPW PF10359.4 ETN99841.1 - 1.6 7.0 10.8 1.9 6.8 7.5 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain HSP90 PF00183.13 ETN99841.1 - 1.7 6.9 22.8 1.9 6.7 15.8 1.1 1 0 0 1 1 1 0 Hsp90 protein DUF2201_N PF13203.1 ETN99841.1 - 1.8 7.6 7.0 2.3 7.3 4.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain XAP5 PF04921.9 ETN99841.1 - 2.2 7.7 13.4 3 7.3 9.3 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator CCDC66 PF15236.1 ETN99841.1 - 2.2 7.8 27.0 2.8 7.5 18.7 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 DUF3381 PF11861.3 ETN99841.1 - 2.3 7.6 22.9 3.6 7.0 15.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Raftlin PF15250.1 ETN99841.1 - 2.6 6.4 7.8 2.8 6.3 5.4 1.0 1 0 0 1 1 1 0 Raftlin DUF2956 PF11169.3 ETN99841.1 - 2.6 8.0 8.8 3.4 7.6 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Pilt PF15453.1 ETN99841.1 - 2.7 7.6 10.0 3 7.4 6.9 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions DUF3530 PF12048.3 ETN99841.1 - 3 6.7 6.9 3.6 6.4 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) HSP70 PF00012.15 ETN99841.1 - 3.2 5.5 12.1 3.7 5.3 8.4 1.0 1 0 0 1 1 1 0 Hsp70 protein PPP4R2 PF09184.6 ETN99841.1 - 3.3 7.1 24.2 4.5 6.7 16.8 1.2 1 0 0 1 1 1 0 PPP4R2 Spore_coat_CotO PF14153.1 ETN99841.1 - 3.3 7.0 19.7 4.1 6.8 13.7 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DDRGK PF09756.4 ETN99841.1 - 3.7 6.9 27.3 4.7 6.5 18.9 1.1 1 0 0 1 1 1 0 DDRGK domain MIP-T3 PF10243.4 ETN99841.1 - 3.7 5.9 24.2 4.2 5.7 16.8 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 eIF-3c_N PF05470.7 ETN99841.1 - 3.8 5.4 14.0 4.4 5.2 9.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RNA_pol_Rpc4 PF05132.9 ETN99841.1 - 3.9 7.4 13.1 5.7 6.9 9.1 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 VID27 PF08553.5 ETN99841.1 - 4.4 5.3 21.9 5.1 5.1 15.2 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein SDA1 PF05285.7 ETN99841.1 - 4.9 6.3 25.6 5.9 6.0 17.7 1.1 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.12 ETN99841.1 - 5.8 5.6 5.9 6.2 5.5 4.1 1.0 1 0 0 1 1 1 0 Presenilin DHHW PF14286.1 ETN99841.1 - 5.8 6.1 8.6 6.8 5.8 5.9 1.1 1 0 0 1 1 1 0 DHHW protein U79_P34 PF03064.11 ETN99841.1 - 6.4 6.2 15.1 7.7 5.9 10.4 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF4220 PF13968.1 ETN99841.1 - 6.8 5.6 6.8 8.1 5.4 4.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DUF3295 PF11702.3 ETN99841.1 - 7.8 5.3 12.0 8.7 5.2 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) DUF2722 PF10846.3 ETN99841.1 - 8 5.3 14.3 9.3 5.1 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.8 ETN99841.1 - 8.4 6.1 22.2 9.9 5.9 15.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cellulose_synt PF03552.9 ETN99841.1 - 8.7 4.5 6.2 9.6 4.3 4.3 1.0 1 0 0 1 1 1 0 Cellulose synthase Hid1 PF12722.2 ETN99841.1 - 9.9 3.6 9.1 11 3.5 6.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein U-box PF04564.10 ETN99842.1 - 3.8e-11 42.8 0.9 1.4e-10 40.9 0.0 2.4 2 1 1 3 3 3 1 U-box domain ENT PF03735.9 ETN99842.1 - 0.017 14.8 1.0 0.045 13.4 0.3 2.1 2 0 0 2 2 2 0 ENT domain FAR1 PF03101.10 ETN99842.1 - 0.049 14.1 4.4 0.16 12.5 3.1 1.9 1 0 0 1 1 1 0 FAR1 DNA-binding domain DUF3450 PF11932.3 ETN99843.1 - 0.03 13.6 8.7 0.032 13.4 4.4 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Atg14 PF10186.4 ETN99843.1 - 0.58 9.0 8.3 0.77 8.6 5.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF87 PF01935.12 ETN99843.1 - 0.9 9.3 5.2 1.3 8.7 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 FadA PF09403.5 ETN99843.1 - 1.8 8.5 11.4 0.37 10.7 5.4 1.6 2 0 0 2 2 2 0 Adhesion protein FadA APG6 PF04111.7 ETN99843.1 - 2.5 7.0 12.0 3.7 6.5 8.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1675 PF07897.6 ETN99843.1 - 4.4 7.0 8.9 0.59 9.9 3.5 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) Mucin PF01456.12 ETN99843.1 - 6.5 6.5 26.3 10 5.8 18.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.6 ETN99843.1 - 8.5 4.2 18.7 12 3.7 12.9 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 V_ATPase_I PF01496.14 ETN99843.1 - 9.7 3.9 8.0 13 3.4 5.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Imm39 PF15600.1 ETN99844.1 - 0.073 12.9 0.2 0.097 12.5 0.1 1.1 1 0 0 1 1 1 0 Immunity protein 39 ABC_tran PF00005.22 ETN99846.1 - 2.2e-05 24.7 0.0 0.00015 22.0 0.0 2.2 3 0 0 3 3 2 1 ABC transporter AAA_5 PF07728.9 ETN99846.1 - 4e-05 23.3 0.0 8.4e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 ETN99846.1 - 0.00027 21.1 0.2 0.0014 18.7 0.0 2.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 ETN99846.1 - 0.0021 17.7 0.2 0.063 12.9 0.1 2.6 1 1 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 ETN99846.1 - 0.0027 17.4 1.3 0.025 14.2 0.2 2.5 2 1 0 2 2 2 1 Archaeal ATPase DUF258 PF03193.11 ETN99846.1 - 0.0034 16.5 0.0 0.0064 15.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SYCE1 PF15233.1 ETN99846.1 - 0.0042 17.0 2.3 0.11 12.4 0.0 2.6 2 0 0 2 2 2 1 Synaptonemal complex central element protein 1 AAA_22 PF13401.1 ETN99846.1 - 0.0043 17.2 0.0 0.012 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 ETN99846.1 - 0.0086 16.5 0.0 0.028 14.9 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein RNA_helicase PF00910.17 ETN99846.1 - 0.031 14.4 0.0 0.071 13.2 0.0 1.8 1 1 0 1 1 1 0 RNA helicase DUF3086 PF11285.3 ETN99846.1 - 0.032 13.0 0.1 2 7.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) KAP_NTPase PF07693.9 ETN99846.1 - 0.033 13.1 0.1 0.34 9.8 0.1 2.2 1 1 0 1 1 1 0 KAP family P-loop domain AAA_14 PF13173.1 ETN99846.1 - 0.043 13.7 0.2 0.19 11.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_21 PF13304.1 ETN99846.1 - 0.052 13.5 0.0 0.14 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 ETN99846.1 - 0.063 12.7 0.1 0.23 10.8 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 ETN99846.1 - 0.063 13.2 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 ETN99846.1 - 0.091 12.1 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 ETN99846.1 - 0.12 12.0 0.7 0.54 9.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 ETN99846.1 - 0.16 11.0 0.0 1.1 8.3 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.1 ETN99846.1 - 0.77 10.0 3.9 3.4 7.9 2.7 2.2 1 1 0 1 1 1 0 AAA domain mRNA_cap_enzyme PF01331.14 ETN99847.1 - 0.00022 20.9 0.8 0.00073 19.2 0.6 1.7 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain ABC_tran PF00005.22 ETN99850.1 - 2.7e-08 34.2 0.0 3.2e-08 33.9 0.0 1.0 1 0 0 1 1 1 1 ABC transporter RQC PF09382.5 ETN99850.1 - 0.092 12.4 0.1 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 RQC domain Cys_rich_VLP PF14194.1 ETN99852.1 - 0.092 12.4 1.0 0.19 11.5 0.1 2.0 3 0 0 3 3 3 0 Cysteine-rich VLP Thioredoxin_8 PF13905.1 ETN99852.1 - 0.17 12.0 5.4 0.2 11.8 3.5 1.4 1 1 0 1 1 1 0 Thioredoxin-like DBB PF14545.1 ETN99853.1 - 0.058 12.9 0.2 0.058 12.9 0.2 1.6 2 0 0 2 2 2 0 Dof, BCAP, and BANK (DBB) motif, MtrA PF04208.9 ETN99853.1 - 0.064 12.6 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A FAM183 PF14886.1 ETN99854.1 - 0.03 14.8 1.1 0.091 13.3 0.8 1.8 1 0 0 1 1 1 0 FAM183A and FAM183B related DUF2258 PF10015.4 ETN99856.1 - 0.11 12.3 0.1 0.35 10.7 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2258) APP_N PF02177.11 ETN99857.1 - 0.017 15.0 1.0 0.022 14.6 0.7 1.2 1 0 0 1 1 1 0 Amyloid A4 N-terminal heparin-binding L27_N PF09060.5 ETN99857.1 - 0.055 13.2 0.1 0.055 13.2 0.1 1.7 2 0 0 2 2 2 0 L27_N DUF4441 PF14536.1 ETN99857.1 - 0.077 12.9 9.2 0.17 11.8 6.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4441) TPK_catalytic PF04263.11 ETN99857.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain DUF3987 PF13148.1 ETN99857.1 - 0.95 7.9 3.3 1.2 7.6 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Kelch_1 PF01344.20 ETN99858.1 - 8.2e-06 25.2 0.8 3e-05 23.4 0.2 2.1 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETN99858.1 - 0.0002 21.3 0.4 0.034 14.3 0.2 3.0 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETN99858.1 - 0.00023 20.8 2.6 0.0081 15.9 0.0 2.8 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETN99858.1 - 0.0013 18.3 0.1 0.12 12.1 0.1 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.1 ETN99858.1 - 0.0031 17.4 0.0 0.26 11.2 0.1 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETN99858.1 - 0.022 14.9 0.0 0.067 13.3 0.0 1.8 2 0 0 2 2 2 0 Galactose oxidase, central domain Monellin PF09200.5 ETN99858.1 - 0.023 14.3 0.1 0.84 9.3 0.0 3.0 3 0 0 3 3 3 0 Monellin HTH_Tnp_Tc3_2 PF01498.13 ETN99859.1 - 5.2e-13 48.8 0.3 8e-13 48.2 0.1 1.5 2 0 0 2 2 2 1 Transposase HTH_21 PF13276.1 ETN99859.1 - 4.1e-05 23.5 0.0 8.6e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 HTH-like domain OmdA PF13376.1 ETN99859.1 - 0.031 13.9 0.2 1.7 8.3 0.0 2.5 2 1 1 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated HTH_20 PF12840.2 ETN99859.1 - 0.04 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain WD40 PF00400.27 ETN99860.1 - 1.5e-18 65.9 5.5 7.3e-11 41.5 0.4 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETN99860.1 - 0.00022 19.5 1.0 0.00045 18.4 0.7 1.7 1 1 0 1 1 1 1 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETN99860.1 - 0.043 13.1 9.3 0.028 13.7 2.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4221) Ricin_B_lectin PF00652.17 ETN99860.1 - 0.23 11.4 3.5 0.18 11.8 1.4 1.5 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain SHP PF03579.8 ETN99861.1 - 0.12 11.7 1.5 0.28 10.5 0.2 2.2 2 0 0 2 2 2 0 Small hydrophobic protein DUF4407 PF14362.1 ETN99861.1 - 0.52 9.2 15.9 1.7 7.5 11.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3394 PF11874.3 ETN99861.1 - 0.79 9.2 5.3 1.2 8.6 2.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3394) CHASE3 PF05227.8 ETN99861.1 - 1.6 8.4 14.9 5.5 6.6 10.1 2.1 1 1 1 2 2 2 0 CHASE3 domain APG6 PF04111.7 ETN99861.1 - 2.8 6.9 37.9 3.3 6.6 16.8 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 zf-C3HC4_2 PF13923.1 ETN99862.1 - 2.6e-05 24.1 2.4 0.00015 21.6 1.7 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETN99862.1 - 0.00017 21.3 3.8 0.00053 19.7 2.6 1.8 1 0 0 1 1 1 1 Ring finger domain Sec20 PF03908.8 ETN99862.1 - 0.0031 17.1 1.3 0.0058 16.3 0.3 2.0 2 0 0 2 2 2 1 Sec20 zf-C3HC4 PF00097.20 ETN99862.1 - 0.058 13.0 5.0 0.4 10.3 3.5 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RPAP2_Rtr1 PF04181.8 ETN99862.1 - 0.076 13.1 0.0 0.076 13.1 0.0 2.2 2 1 0 2 2 2 0 Rtr1/RPAP2 family DUF1644 PF07800.7 ETN99862.1 - 0.34 10.7 10.5 1.2 8.9 7.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) Cys_knot PF00007.17 ETN99862.1 - 0.38 10.8 10.3 0.1 12.6 4.3 2.0 2 0 0 2 2 2 0 Cystine-knot domain zf-C3HC4_3 PF13920.1 ETN99862.1 - 0.47 10.1 5.2 1.5 8.5 3.6 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SID-1_RNA_chan PF13965.1 ETN99863.1 - 0.068 11.3 0.2 0.068 11.3 0.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Cnd1_N PF12922.2 ETN99863.1 - 0.28 10.7 2.4 0.19 11.3 0.2 1.9 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term WD40 PF00400.27 ETN99865.1 - 7.9e-12 44.5 2.0 2e-06 27.4 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat LPP PF04728.8 ETN99868.1 - 0.059 13.1 0.0 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Sulfotransfer_1 PF00685.22 ETN99869.1 - 5.2e-06 25.9 0.2 2.7e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 ETN99869.1 - 0.006 17.5 0.0 0.015 16.2 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase family Sulphotransf PF09037.5 ETN99869.1 - 0.013 15.0 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 Stf0 sulphotransferase HTH_23 PF13384.1 ETN99869.1 - 0.069 12.8 0.0 1 9.1 0.0 2.5 2 0 0 2 2 2 0 Homeodomain-like domain DUF1104 PF06518.6 ETN99870.1 - 0.87 9.7 7.3 0.12 12.4 1.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) Glyco_hydro_32C PF08244.7 ETN99875.1 - 0.068 13.5 0.2 0.11 12.9 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 C terminal DUF547 PF04784.9 ETN99875.1 - 0.098 12.5 0.2 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF547 TPR_12 PF13424.1 ETN99876.1 - 6.3e-46 154.2 23.7 6.3e-20 70.8 2.3 3.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETN99876.1 - 1.2e-30 104.9 24.7 4.6e-13 48.5 6.7 4.1 2 1 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 ETN99876.1 - 3.7e-28 95.9 36.4 1.8e-06 27.2 0.5 5.9 5 1 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETN99876.1 - 4.9e-26 88.5 28.8 6.5e-06 25.6 0.2 5.3 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.1 ETN99876.1 - 6.9e-24 81.7 12.8 0.00019 20.9 0.1 5.5 5 1 0 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETN99876.1 - 9.7e-23 79.3 2.1 8.7e-06 25.4 0.1 5.8 5 1 0 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.1 ETN99876.1 - 4.2e-18 63.7 38.2 0.00023 20.7 3.1 6.0 5 2 0 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.1 ETN99876.1 - 3e-12 46.0 0.0 0.67 10.7 0.0 5.6 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETN99876.1 - 3.7e-12 45.8 7.7 0.15 12.5 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETN99876.1 - 2.4e-10 40.8 5.5 1.1e-05 25.9 0.3 3.9 1 1 2 4 4 4 2 Tetratricopeptide repeat SNAP PF14938.1 ETN99876.1 - 1.5e-09 37.3 11.6 0.0027 16.9 2.3 2.8 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP SHNi-TPR PF10516.4 ETN99876.1 - 2.6e-09 36.1 0.1 0.096 11.9 0.0 5.2 5 0 0 5 5 5 2 SHNi-TPR Apc3 PF12895.2 ETN99876.1 - 4.3e-09 36.3 19.1 0.00075 19.5 4.3 3.1 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETN99876.1 - 5.7e-08 32.9 3.3 0.00073 19.8 0.4 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 ETN99876.1 - 2.8e-07 30.3 17.5 0.035 13.9 0.4 5.0 5 0 0 5 5 5 3 MIT (microtubule interacting and transport) domain DUF2225 PF09986.4 ETN99876.1 - 1.1e-06 28.2 16.5 0.01 15.2 3.1 4.1 1 1 3 4 4 4 3 Uncharacterized protein conserved in bacteria (DUF2225) TPR_3 PF07720.7 ETN99876.1 - 2.4e-05 24.0 25.1 0.00032 20.4 3.6 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat RPN7 PF10602.4 ETN99876.1 - 7.2e-05 22.2 11.9 0.099 12.0 1.0 3.4 2 1 1 3 3 3 3 26S proteasome subunit RPN7 Foie-gras_1 PF11817.3 ETN99876.1 - 0.00015 21.2 3.3 0.0027 17.2 0.1 2.7 1 1 2 3 3 3 1 Foie gras liver health family 1 TPR_17 PF13431.1 ETN99876.1 - 0.00017 21.5 26.7 0.087 13.0 0.7 6.3 5 2 1 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETN99876.1 - 0.018 14.8 0.0 0.26 11.1 0.0 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_5 PF12688.2 ETN99876.1 - 0.024 14.6 1.9 0.36 10.8 0.0 3.4 3 2 2 5 5 5 0 Tetratrico peptide repeat Fib_alpha PF08702.5 ETN99876.1 - 0.055 13.6 2.4 0.45 10.6 1.3 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family NSF PF02071.15 ETN99876.1 - 0.088 13.3 15.3 3.5 8.5 0.2 5.9 5 0 0 5 5 5 0 Aromatic-di-Alanine (AdAR) repeat Sel1 PF08238.7 ETN99876.1 - 0.11 13.1 17.8 1.8 9.3 0.1 5.0 5 1 0 5 5 4 0 Sel1 repeat Rapsyn_N PF10579.4 ETN99876.1 - 0.2 11.4 2.0 27 4.6 0.2 3.8 3 1 1 4 4 4 0 Rapsyn N-terminal myristoylation and linker region HEPN PF05168.9 ETN99876.1 - 0.27 11.1 6.6 0.24 11.2 0.8 2.7 2 2 0 2 2 2 0 HEPN domain Spore_III_AB PF09548.5 ETN99876.1 - 0.32 10.7 1.8 1.4 8.6 0.4 2.3 1 1 2 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Lambda_Kil PF06301.6 ETN99876.1 - 0.33 10.4 2.7 1.2 8.6 0.1 2.6 3 0 0 3 3 2 0 Bacteriophage lambda Kil protein DUF627 PF04781.7 ETN99876.1 - 0.43 10.2 10.2 3.5 7.2 0.4 3.7 1 1 1 2 2 2 0 Protein of unknown function (DUF627) Alpha-amylase_N PF02903.9 ETN99876.1 - 0.5 10.3 5.3 6.3 6.7 0.1 3.3 2 1 2 4 4 4 0 Alpha amylase, N-terminal ig-like domain DUF386 PF04074.7 ETN99876.1 - 0.64 9.5 6.6 0.21 11.1 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF386) DUF2989 PF11207.3 ETN99876.1 - 2.7 7.3 14.8 8 5.8 2.8 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2989) Inhibitor_I29 PF08246.7 ETN99876.1 - 2.9 8.2 15.4 3.4 8.0 2.9 3.7 2 2 2 4 4 4 0 Cathepsin propeptide inhibitor domain (I29) Sec5 PF15469.1 ETN99876.1 - 3.6 7.2 15.7 1.9 8.1 0.8 3.8 2 1 2 4 4 4 0 Exocyst complex component Sec5 Prefoldin PF02996.12 ETN99876.1 - 6.8 6.3 10.5 59 3.3 0.0 4.0 2 1 2 4 4 4 0 Prefoldin subunit SPO22 PF08631.5 ETN99876.1 - 9.2 5.2 14.4 18 4.3 0.2 3.9 3 1 0 4 4 4 0 Meiosis protein SPO22/ZIP4 like RabGAP-TBC PF00566.13 ETN99877.1 - 9.7e-52 175.5 5.0 9.7e-52 175.5 3.5 3.4 3 1 0 3 3 3 1 Rab-GTPase-TBC domain MMPL PF03176.10 ETN99878.1 - 2.4e-16 59.3 7.3 7.8e-14 51.1 0.2 2.9 1 1 1 2 2 2 2 MMPL family Kelch_6 PF13964.1 ETN99879.1 - 0.0055 16.8 0.2 0.28 11.4 0.0 2.8 2 1 1 3 3 3 1 Kelch motif Kelch_3 PF13415.1 ETN99879.1 - 0.037 14.2 0.0 0.27 11.4 0.0 2.2 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_4 PF13418.1 ETN99879.1 - 0.31 10.8 1.5 7.2 6.4 0.0 2.9 2 1 1 3 3 3 0 Galactose oxidase, central domain WD40 PF00400.27 ETN99880.1 - 4.2e-10 39.0 1.0 2.7e-08 33.3 0.0 2.7 2 1 0 2 2 2 2 WD domain, G-beta repeat Kelch_6 PF13964.1 ETN99881.1 - 2.3e-10 40.1 10.2 1.7e-05 24.7 0.3 5.2 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.1 ETN99881.1 - 1.9e-09 37.1 2.3 0.001 18.7 0.0 4.5 3 1 1 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.1 ETN99881.1 - 9.1e-06 25.5 13.3 0.0033 17.3 0.5 5.2 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.20 ETN99881.1 - 1.9e-05 24.0 6.9 0.0012 18.3 0.5 4.2 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 ETN99881.1 - 8.9e-05 22.1 3.4 0.045 13.5 0.1 4.9 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.1 ETN99881.1 - 0.00012 22.1 1.5 0.0033 17.5 0.0 3.9 6 0 0 6 6 6 1 Galactose oxidase, central domain WD40 PF00400.27 ETN99882.1 - 1.3e-31 107.3 12.7 1.1e-10 40.9 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETN99882.1 - 4.7e-07 28.3 0.6 0.00057 18.1 0.1 2.9 3 0 0 3 3 3 2 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETN99882.1 - 5.1e-06 26.7 1.2 5.1e-06 26.7 0.8 3.3 3 1 2 5 5 5 1 TRAF-type zinc finger Cluap1 PF10234.4 ETN99882.1 - 0.14 11.3 8.5 0.23 10.6 5.9 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF342 PF03961.8 ETN99882.1 - 0.35 9.2 6.0 0.3 9.4 3.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF342) IncA PF04156.9 ETN99882.1 - 5.5 6.5 7.3 10 5.6 5.0 1.4 1 0 0 1 1 1 0 IncA protein PT PF04886.7 ETN99884.1 - 4.8e-07 28.9 17.5 4.8e-07 28.9 12.1 2.9 1 1 1 2 2 2 1 PT repeat gpUL132 PF11359.3 ETN99884.1 - 5.9e-05 22.5 1.6 0.0001 21.7 1.1 1.4 1 0 0 1 1 1 1 Glycoprotein UL132 TMEM154 PF15102.1 ETN99884.1 - 0.00016 21.3 0.6 0.00036 20.2 0.4 1.7 1 0 0 1 1 1 1 TMEM154 protein family SAM_2 PF07647.12 ETN99884.1 - 0.0032 17.2 0.1 0.0061 16.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETN99884.1 - 0.0042 17.2 0.0 0.0069 16.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4448 PF14610.1 ETN99884.1 - 0.0085 15.5 0.5 0.026 14.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) SKG6 PF08693.5 ETN99884.1 - 0.044 13.1 0.0 0.12 11.7 0.0 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.1 ETN99884.1 - 0.076 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.15 ETN99884.1 - 0.079 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Mid2 PF04478.7 ETN99884.1 - 2.2 7.6 11.9 0.12 11.7 4.2 2.0 2 1 0 2 2 2 0 Mid2 like cell wall stress sensor zf-CCHC_4 PF14392.1 ETN99885.1 - 0.057 13.0 4.4 0.16 11.6 1.6 2.7 2 0 0 2 2 2 0 Zinc knuckle zf-TRAF PF02176.13 ETN99885.1 - 3.3 8.1 10.0 0.78 10.1 3.5 2.3 2 0 0 2 2 2 0 TRAF-type zinc finger OST3_OST6 PF04756.8 ETN99886.1 - 0.0072 15.9 0.9 0.013 15.0 0.6 1.5 1 0 0 1 1 1 1 OST3 / OST6 family DUF3088 PF11287.3 ETN99886.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3088) AAA_22 PF13401.1 ETN99888.1 - 0.019 15.0 0.0 0.1 12.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 ETN99888.1 - 0.05 13.7 0.0 0.079 13.1 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Aldo_ket_red PF00248.16 ETN99888.1 - 0.052 12.3 0.1 0.17 10.6 0.1 1.8 1 1 0 1 1 1 0 Aldo/keto reductase family IstB_IS21 PF01695.12 ETN99888.1 - 0.13 11.6 0.0 0.85 9.0 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein Dict-STAT-coil PF09267.5 ETN99889.1 - 0.85 9.8 3.9 0.99 9.6 1.1 2.1 1 1 1 2 2 2 0 Dictyostelium STAT, coiled coil WD40 PF00400.27 ETN99890.1 - 1.2e-09 37.7 2.0 2.3e-09 36.7 1.4 1.5 1 0 0 1 1 1 1 WD domain, G-beta repeat IBR PF01485.16 ETN99891.1 - 0.017 15.0 11.9 0.037 13.8 8.3 1.7 1 0 0 1 1 1 0 IBR domain zf-RING_4 PF14570.1 ETN99891.1 - 9.7 5.8 10.9 18 4.9 7.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Tubulin_C PF03953.12 ETN99892.1 - 1.1e-22 80.4 0.0 1.4e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 Tubulin C-terminal domain CALCOCO1 PF07888.6 ETN99894.1 - 0.019 13.3 11.6 0.022 13.0 8.0 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF573 PF04504.9 ETN99894.1 - 0.026 14.8 0.6 0.026 14.8 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function, DUF573 NCKAP5 PF15246.1 ETN99894.1 - 0.031 13.6 14.6 0.036 13.4 10.1 1.0 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein Mnd1 PF03962.10 ETN99894.1 - 0.033 13.8 10.5 0.043 13.4 7.3 1.2 1 0 0 1 1 1 0 Mnd1 family NusG PF02357.14 ETN99894.1 - 0.12 12.5 0.3 0.12 12.5 0.2 2.2 2 0 0 2 2 2 0 Transcription termination factor nusG Spc7 PF08317.6 ETN99894.1 - 0.45 9.1 11.2 0.6 8.7 7.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4509 PF14970.1 ETN99894.1 - 0.53 9.9 6.0 0.78 9.3 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) APG6 PF04111.7 ETN99894.1 - 0.65 8.9 12.8 1.1 8.2 8.9 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 Bacillus_HBL PF05791.6 ETN99894.1 - 0.68 9.2 6.5 0.86 8.9 3.4 1.9 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) NST1 PF13945.1 ETN99894.1 - 1.3 9.1 15.5 0.99 9.4 5.5 2.1 1 1 1 2 2 2 0 Salt tolerance down-regulator V_ATPase_I PF01496.14 ETN99894.1 - 1.8 6.3 6.6 1.9 6.2 4.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OmpH PF03938.9 ETN99894.1 - 2.3 8.1 7.7 2.6 7.9 5.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.10 ETN99894.1 - 2.3 7.3 9.4 2.6 7.1 6.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-Q PF13094.1 ETN99894.1 - 6.2 6.8 13.7 11 5.9 8.9 1.6 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit YgaB PF14182.1 ETN99894.1 - 6.8 6.9 14.7 1 9.6 4.4 2.4 1 1 1 2 2 2 0 YgaB-like protein Nup54 PF13874.1 ETN99894.1 - 7.1 6.2 10.9 19 4.9 7.6 1.6 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 IncA PF04156.9 ETN99894.1 - 8 6.0 8.1 10 5.6 5.6 1.2 1 0 0 1 1 1 0 IncA protein ERM PF00769.14 ETN99895.1 - 0.043 13.3 41.4 0.051 13.1 28.7 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF2894 PF11445.3 ETN99895.1 - 0.065 13.4 17.2 0.082 13.1 11.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) DUF724 PF05266.9 ETN99895.1 - 0.07 12.7 35.2 0.3 10.7 9.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Tropomyosin_1 PF12718.2 ETN99895.1 - 0.089 12.6 40.6 0.13 12.1 28.1 1.2 1 0 0 1 1 1 0 Tropomyosin like CDC37_N PF03234.9 ETN99895.1 - 0.14 12.4 28.8 0.16 12.2 20.0 1.0 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding CENP-F_leu_zip PF10473.4 ETN99895.1 - 0.19 11.5 38.1 0.077 12.8 11.2 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.3 ETN99895.1 - 0.2 10.8 32.0 0.22 10.7 8.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF3584 PF12128.3 ETN99895.1 - 0.29 8.4 34.5 0.34 8.2 23.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.6 ETN99895.1 - 0.37 9.3 32.5 0.51 8.9 22.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 ETN99895.1 - 0.61 9.6 35.9 1.9 8.0 24.9 1.7 1 1 0 1 1 1 0 IncA protein IFT57 PF10498.4 ETN99895.1 - 0.78 8.4 31.4 1.1 7.8 21.6 1.4 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Bacillus_HBL PF05791.6 ETN99895.1 - 1.1 8.6 28.2 0.17 11.2 6.5 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Atg14 PF10186.4 ETN99895.1 - 2.1 7.1 30.2 3 6.7 20.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CCDC84 PF14968.1 ETN99895.1 - 2.5 7.5 21.4 3 7.2 14.8 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 Lebercilin PF15619.1 ETN99895.1 - 4.5 6.6 42.4 4.3 6.7 13.3 2.0 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease CALCOCO1 PF07888.6 ETN99895.1 - 7.1 4.7 26.5 9.5 4.3 18.3 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like APG6 PF04111.7 ETN99895.1 - 7.3 5.5 40.3 3.4 6.6 11.0 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Ax_dynein_light PF10211.4 ETN99895.1 - 7.3 6.3 42.2 8 6.2 11.9 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain HHA PF05321.6 ETN99895.1 - 7.7 6.7 7.5 1.1 9.4 1.0 2.6 1 1 1 2 2 2 0 Haemolysin expression modulating protein SOBP PF15279.1 ETN99895.1 - 7.7 6.7 11.1 8.9 6.5 7.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Rootletin PF15035.1 ETN99895.1 - 8.3 6.3 32.9 1.6 8.6 10.1 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF3552 PF12072.3 ETN99896.1 - 0.0019 17.4 102.3 0.045 12.9 30.3 4.4 1 1 2 3 3 3 3 Domain of unknown function (DUF3552) ATG16 PF08614.6 ETN99896.1 - 0.77 9.5 77.6 0.67 9.7 36.4 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) NACHT PF05729.7 ETN99898.1 - 0.017 14.7 0.8 0.12 12.0 0.1 2.6 3 0 0 3 3 3 0 NACHT domain Ribosomal_L22 PF00237.14 ETN99898.1 - 0.024 14.5 0.1 0.18 11.7 0.0 2.5 1 1 0 1 1 1 0 Ribosomal protein L22p/L17e Kelch_6 PF13964.1 ETN99899.1 - 1.2e-08 34.7 1.8 0.00014 21.8 0.4 2.4 1 1 1 2 2 2 2 Kelch motif Kelch_4 PF13418.1 ETN99899.1 - 7.4e-07 28.8 0.0 0.0014 18.3 0.0 2.3 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETN99899.1 - 1.8e-06 27.4 0.4 0.00018 21.1 0.1 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.20 ETN99899.1 - 3.7e-06 26.3 1.7 8.6e-05 22.0 0.7 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.1 ETN99899.1 - 0.011 15.6 0.3 0.65 10.0 0.3 2.3 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.1 ETN99899.1 - 0.057 13.6 0.1 0.35 11.0 0.0 2.2 3 0 0 3 3 3 0 Galactose oxidase, central domain DUF4488 PF14869.1 ETN99899.1 - 0.079 12.5 2.7 6.3 6.3 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4488) Methyltransf_FA PF12248.3 ETN99899.1 - 0.094 12.7 0.2 0.49 10.4 0.0 2.0 2 0 0 2 2 2 0 Farnesoic acid 0-methyl transferase DUF148 PF02520.12 ETN99900.1 - 0.058 13.1 0.2 0.08 12.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF148 RB_A PF01858.12 ETN99900.1 - 0.26 10.9 2.4 0.24 11.0 0.5 1.6 2 0 0 2 2 2 0 Retinoblastoma-associated protein A domain FBA_2 PF07735.12 ETN99900.1 - 1.9 8.3 5.9 7.8 6.4 1.0 2.4 1 1 1 2 2 2 0 F-box associated PD40 PF07676.7 ETN99901.1 - 4.1e-09 35.8 0.4 4.9 6.9 0.0 6.1 6 0 0 6 6 6 3 WD40-like Beta Propeller Repeat eIF2A PF08662.6 ETN99901.1 - 2.7e-07 30.4 1.5 0.0032 17.1 0.0 3.1 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 ETN99901.1 - 6.7e-06 25.7 2.1 0.36 10.7 0.0 5.3 6 0 0 6 6 6 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 ETN99901.1 - 6.7e-06 25.1 1.0 0.071 11.8 0.1 3.1 1 1 2 3 3 3 2 Coatomer WD associated region SGL PF08450.7 ETN99901.1 - 0.063 12.6 0.5 0.41 9.9 0.1 2.3 1 1 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region Nbas_N PF15492.1 ETN99901.1 - 0.096 11.7 0.2 7.4 5.5 0.0 3.1 1 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Mid2 PF04478.7 ETN99901.1 - 0.85 9.0 8.5 12 5.2 0.0 4.1 2 1 2 4 4 4 0 Mid2 like cell wall stress sensor Proteasome_A_N PF10584.4 ETN99901.1 - 1.8 7.9 4.8 17 4.8 0.1 3.9 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Tropomyosin_1 PF12718.2 ETN99902.1 - 0.012 15.5 5.5 0.014 15.2 3.8 1.1 1 0 0 1 1 1 0 Tropomyosin like MscS_porin PF12795.2 ETN99902.1 - 0.024 13.9 4.2 0.031 13.5 2.8 1.3 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF3882 PF07066.6 ETN99902.1 - 0.028 14.2 0.1 0.032 14.0 0.1 1.1 1 0 0 1 1 1 0 Lactococcus phage M3 protein Spc7 PF08317.6 ETN99902.1 - 0.052 12.2 6.3 0.055 12.1 4.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.3 ETN99902.1 - 0.14 11.9 11.4 0.29 10.9 7.9 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 ETN99902.1 - 0.37 10.3 7.6 0.43 10.1 5.3 1.4 1 1 0 1 1 1 0 IncA protein Syntaphilin PF15290.1 ETN99902.1 - 0.39 10.1 3.0 0.46 9.9 2.1 1.1 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp SlyX PF04102.7 ETN99902.1 - 0.46 10.9 2.3 0.7 10.3 1.2 1.6 1 1 0 1 1 1 0 SlyX IL2 PF00715.12 ETN99902.1 - 0.7 9.6 4.8 3.5 7.3 0.2 2.2 1 1 1 2 2 2 0 Interleukin 2 C2 PF00168.25 ETN99903.1 - 6.9e-07 29.0 0.2 1.6e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 C2 domain NOSIC PF08060.8 ETN99904.1 - 0.039 13.7 0.2 0.25 11.1 0.1 2.4 1 1 0 1 1 1 0 NOSIC (NUC001) domain DUF4163 PF13739.1 ETN99904.1 - 0.33 11.7 6.3 0.93 10.3 4.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4163) OAD_gamma PF04277.8 ETN99908.1 - 8.2 6.8 8.1 12 6.3 0.0 3.3 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Strumpellin PF10266.4 ETN99909.1 - 0.49 7.7 2.6 0.66 7.3 1.8 1.0 1 0 0 1 1 1 0 Hereditary spastic paraplegia protein strumpellin Menin PF05053.8 ETN99909.1 - 1.2 7.2 7.6 1.7 6.6 5.3 1.2 1 0 0 1 1 1 0 Menin Hid1 PF12722.2 ETN99909.1 - 9.6 3.7 19.0 12 3.3 13.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein WD40 PF00400.27 ETN99911.1 - 1.1e-90 294.5 20.0 1.3e-14 53.4 0.1 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETN99911.1 - 1.1e-10 40.3 10.8 0.0035 15.5 0.2 5.2 1 1 4 5 5 5 5 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETN99911.1 - 1.4e-10 41.0 7.0 2.1e-06 27.4 1.1 3.1 1 1 1 2 2 2 2 PQQ-like domain Gmad1 PF10647.4 ETN99911.1 - 1.6e-10 40.8 4.0 9.9e-05 21.8 0.0 2.2 1 1 1 2 2 2 2 Lipoprotein LpqB beta-propeller domain eIF2A PF08662.6 ETN99911.1 - 2e-09 37.4 0.0 0.0011 18.7 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A DUF4072 PF13284.1 ETN99911.1 - 0.00011 22.2 0.0 14 6.0 0.0 5.3 6 0 0 6 6 6 0 Domain of unknown function (DUF4072) DUF1258 PF06869.7 ETN99911.1 - 0.00029 19.9 0.1 1.2 8.1 0.0 3.2 1 1 1 3 3 3 1 Protein of unknown function (DUF1258) Nucleoporin_N PF08801.6 ETN99911.1 - 0.00094 18.0 15.3 0.04 12.6 2.3 5.1 1 1 3 4 4 4 1 Nup133 N terminal like DUF3732 PF12532.3 ETN99911.1 - 0.0016 17.9 1.7 4.5 6.7 0.0 4.3 2 2 1 4 4 4 1 Protein of unknown function (DUF3732) Cytochrom_D1 PF02239.11 ETN99911.1 - 0.0021 16.4 2.7 0.55 8.4 0.2 3.0 1 1 3 4 4 4 2 Cytochrome D1 heme domain DUF1652 PF07865.6 ETN99911.1 - 0.0031 17.0 0.1 4.8 6.8 0.0 4.4 5 0 0 5 5 5 1 Protein of unknown function (DUF1652) PQQ PF01011.16 ETN99911.1 - 0.0038 16.6 0.0 11 5.7 0.0 4.3 5 0 0 5 5 5 0 PQQ enzyme repeat TolB_N PF04052.8 ETN99911.1 - 0.007 16.4 0.0 66 3.6 0.0 4.9 6 0 0 6 6 5 0 TolB amino-terminal domain AMIN PF11741.3 ETN99911.1 - 0.026 14.4 0.0 60 3.7 0.0 3.7 2 2 2 4 4 4 0 AMIN domain Me-amine-dh_H PF06433.6 ETN99911.1 - 0.027 13.1 0.0 5.8 5.4 0.0 3.0 1 1 3 4 4 4 0 Methylamine dehydrogenase heavy chain (MADH) PD40 PF07676.7 ETN99911.1 - 0.079 12.6 10.9 14 5.4 0.1 5.5 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat NYD-SP28_assoc PF14775.1 ETN99911.1 - 0.19 11.4 3.7 1.2e+02 2.4 0.0 5.2 6 0 0 6 6 6 0 Sperm tail C-terminal domain Proteasome_A_N PF10584.4 ETN99911.1 - 4.4 6.7 12.4 25 4.3 0.0 5.6 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature Microvir_J PF04726.8 ETN99911.1 - 5.7 6.9 6.5 29 4.7 0.0 4.7 6 0 0 6 6 6 0 Microvirus J protein NQRA_SLBB PF11973.3 ETN99911.1 - 6.4 7.2 15.8 70 3.8 0.1 5.9 6 0 0 6 6 6 0 NQRA C-terminal domain ABC_membrane_2 PF06472.10 ETN99913.1 - 3.3e-07 29.7 6.8 3.8e-07 29.5 4.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 Transposase_mut PF00872.13 ETN99914.1 - 0.1 11.1 0.1 0.2 10.1 0.0 1.5 2 0 0 2 2 2 0 Transposase, Mutator family RNB PF00773.14 ETN99917.1 - 0.057 12.7 0.1 0.057 12.7 0.0 1.1 1 0 0 1 1 1 0 RNB domain zf-C3HC4_2 PF13923.1 ETN99917.1 - 0.11 12.4 3.0 7.3 6.7 0.0 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) R3H-assoc PF13902.1 ETN99918.1 - 0.056 13.4 0.6 0.36 10.8 0.0 2.0 2 0 0 2 2 2 0 R3H-associated N-terminal domain DUF4028 PF13220.1 ETN99918.1 - 0.88 9.2 5.5 3.6 7.3 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4028) DUF2963 PF11178.3 ETN99919.1 - 3.9 6.9 6.4 0.47 9.9 1.3 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2963) WD40 PF00400.27 ETN99920.1 - 1.2e-34 116.9 18.1 1.9e-12 46.5 0.1 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETN99920.1 - 1e-05 23.9 3.3 0.16 10.0 0.0 3.8 1 1 2 4 4 4 3 Nucleoporin Nup120/160 SspB PF04386.8 ETN99921.1 - 0.077 12.5 0.0 0.077 12.5 0.0 2.2 1 1 1 2 2 2 0 Stringent starvation protein B DUF3549 PF12069.3 ETN99921.1 - 0.12 11.1 3.0 0.15 10.8 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) PMC2NT PF08066.7 ETN99921.1 - 1.1 9.5 3.8 25 5.2 0.1 2.5 2 0 0 2 2 2 0 PMC2NT (NUC016) domain RCC1 PF00415.13 ETN99922.1 - 1.2e-28 99.0 1.5 1.1e-09 38.3 0.0 7.5 8 0 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETN99922.1 - 0.0011 18.4 15.1 0.36 10.4 0.4 5.0 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat Ndc1_Nup PF09531.5 ETN99922.1 - 8.1 4.7 8.6 12 4.1 6.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GDYXXLXY PF14345.1 ETN99924.1 - 0.029 14.2 2.7 0.054 13.3 1.9 1.6 1 1 0 1 1 1 0 GDYXXLXY protein PDZ_2 PF13180.1 ETN99924.1 - 0.32 10.9 2.1 0.35 10.7 0.8 1.6 2 0 0 2 2 2 0 PDZ domain Kelch_4 PF13418.1 ETN99925.1 - 9.4e-09 34.9 0.0 0.00023 20.8 0.0 2.7 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETN99925.1 - 2.3e-06 27.5 0.4 0.00066 19.7 0.0 2.9 2 1 1 3 3 3 1 Kelch motif Kelch_3 PF13415.1 ETN99925.1 - 0.011 15.9 0.0 0.025 14.7 0.0 1.7 1 0 0 1 1 1 0 Galactose oxidase, central domain Kelch_2 PF07646.10 ETN99925.1 - 0.027 14.2 1.3 0.36 10.6 0.1 3.0 3 0 0 3 3 3 0 Kelch motif Kelch_1 PF01344.20 ETN99925.1 - 0.062 12.8 0.1 0.062 12.8 0.1 3.1 5 0 0 5 5 5 0 Kelch motif FH2 PF02181.18 ETN99926.1 - 8.4e-37 126.9 4.2 9.2e-37 126.7 2.9 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain DUF1804 PF08822.6 ETN99926.1 - 0.026 14.2 0.3 0.074 12.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) DUF4559 PF15112.1 ETN99926.1 - 0.028 13.6 0.3 0.037 13.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DUF3989 PF13150.1 ETN99926.1 - 0.084 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) DUF3615 PF12274.3 ETN99927.1 - 0.42 10.9 3.4 0.56 10.5 2.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3615) DUF1829 PF08862.5 ETN99928.1 - 0.095 12.9 2.9 5.3 7.4 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF1829 CDC37_C PF08564.5 ETN99928.1 - 0.27 11.0 7.1 3 7.7 0.0 2.3 2 0 0 2 2 2 0 Cdc37 C terminal domain AAA PF00004.24 ETN99929.1 - 0.0031 17.7 0.0 0.17 12.0 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Phage_portal PF04860.7 ETN99929.1 - 0.0043 15.7 0.0 0.02 13.6 0.0 1.9 2 0 0 2 2 2 1 Phage portal protein AAA_5 PF07728.9 ETN99929.1 - 0.063 12.9 0.2 15 5.3 0.0 3.3 2 2 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETN99929.1 - 0.1 12.7 3.9 0.49 10.5 0.1 3.8 4 1 0 4 4 4 0 AAA domain APOC4 PF15119.1 ETN99931.1 - 0.039 13.9 0.0 0.092 12.7 0.0 1.6 1 0 0 1 1 1 0 Apolipoprotein C4 MIF4G PF02854.14 ETN99932.1 - 8e-25 87.4 7.0 1.9e-24 86.2 4.8 1.7 1 0 0 1 1 1 1 MIF4G domain PAM2 PF07145.10 ETN99933.1 - 0.003 16.9 0.0 0.011 15.1 0.0 2.0 1 0 0 1 1 1 1 Ataxin-2 C-terminal region DASH_Dam1 PF08653.5 ETN99933.1 - 1 9.1 3.1 2.6 7.8 0.5 2.4 2 0 0 2 2 2 0 DASH complex subunit Dam1 Init_tRNA_PT PF04179.7 ETN99934.1 - 0.00032 19.7 1.1 0.00032 19.6 0.8 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase DUF1564 PF07600.6 ETN99934.1 - 0.0012 18.2 2.0 0.0014 17.9 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1564) Hamartin PF04388.7 ETN99934.1 - 0.031 12.9 1.5 0.033 12.8 1.0 1.0 1 0 0 1 1 1 0 Hamartin protein BEN PF10523.4 ETN99934.1 - 0.039 14.0 0.1 0.055 13.5 0.1 1.4 1 1 0 1 1 1 0 BEN domain Pox_C7_F8A PF03287.9 ETN99934.1 - 0.053 13.2 2.1 0.059 13.0 1.5 1.1 1 0 0 1 1 1 0 Poxvirus C7/F8A protein Prp18 PF02840.10 ETN99934.1 - 0.16 11.7 3.5 0.18 11.6 2.4 1.1 1 0 0 1 1 1 0 Prp18 domain Viral_env_E26 PF11050.3 ETN99934.1 - 0.21 10.7 6.1 0.21 10.7 4.2 1.1 1 0 0 1 1 1 0 Virus envelope protein E26 Sds3 PF08598.6 ETN99934.1 - 0.27 10.7 3.5 0.42 10.1 2.4 1.5 1 1 0 1 1 1 0 Sds3-like Matrilin_ccoil PF10393.4 ETN99934.1 - 2 7.8 6.8 0.6 9.5 1.2 2.5 1 1 2 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin RVT_1 PF00078.22 ETN99935.1 - 7.2e-08 32.0 0.0 1.4e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LVIVD PF08309.6 ETN99936.1 - 0.0027 16.6 1.5 1.6 7.8 0.2 2.4 2 0 0 2 2 2 2 LVIVD repeat Kelch_6 PF13964.1 ETN99936.1 - 0.0051 16.9 0.0 0.0099 16.0 0.0 1.4 1 0 0 1 1 1 1 Kelch motif Kelch_5 PF13854.1 ETN99936.1 - 0.047 13.6 0.1 0.096 12.6 0.0 1.6 1 0 0 1 1 1 0 Kelch motif Fascin PF06268.8 ETN99937.1 - 0.6 10.2 3.7 0.76 9.8 0.1 2.7 2 1 1 3 3 3 0 Fascin domain DUF960 PF06124.6 ETN99937.1 - 4 7.7 5.6 0.64 10.2 0.2 2.3 2 2 0 2 2 2 0 Staphylococcal protein of unknown function (DUF960) DPM3 PF08285.6 ETN99938.1 - 0.27 11.0 4.3 3 7.7 0.0 3.1 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Kelch_5 PF13854.1 ETN99939.1 - 0.076 12.9 2.2 4.2 7.4 0.2 3.2 3 0 0 3 3 3 0 Kelch motif TPR_12 PF13424.1 ETN99941.1 - 6.6e-15 54.8 0.8 2.2e-11 43.5 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETN99941.1 - 1.4e-12 46.5 6.9 1.6e-05 24.3 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETN99941.1 - 3.9e-12 45.1 4.5 0.00042 20.0 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETN99941.1 - 4.9e-11 42.1 3.0 7.6e-09 35.0 0.1 2.5 2 1 0 2 2 2 2 TPR repeat TPR_8 PF13181.1 ETN99941.1 - 1.9e-08 33.4 7.9 0.0016 18.0 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETN99941.1 - 2.3e-06 27.3 0.0 0.15 12.0 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETN99941.1 - 1.7e-05 24.2 1.7 0.0057 16.3 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETN99941.1 - 0.00049 20.4 0.0 0.85 10.4 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETN99941.1 - 0.0026 17.6 1.9 0.039 13.8 0.5 2.4 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat Apc3 PF12895.2 ETN99941.1 - 0.003 17.6 4.2 0.12 12.5 1.3 2.6 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 ETN99941.1 - 0.033 14.3 6.8 5.6 7.4 0.5 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETN99941.1 - 0.035 14.5 0.3 11 6.6 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_S80 PF07230.6 ETN99942.1 - 0.04 12.2 5.3 0.049 11.9 3.7 1.0 1 0 0 1 1 1 0 Bacteriophage T4-like capsid assembly protein (Gp20) Peptidase_M6 PF05547.6 ETN99942.1 - 0.49 8.3 3.5 0.51 8.3 2.4 1.0 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 PemK PF02452.12 ETN99942.1 - 0.58 10.3 4.7 0.66 10.1 3.0 1.3 1 1 0 1 1 1 0 PemK-like protein Iron_permease PF04120.7 ETN99942.1 - 1.5 8.4 3.6 1.6 8.2 2.5 1.1 1 0 0 1 1 1 0 Low affinity iron permease mRNA_cap_C PF03919.10 ETN99943.1 - 0.032 14.5 1.2 0.13 12.5 0.3 2.2 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain Ion_trans_N PF08412.5 ETN99943.1 - 0.07 12.4 0.0 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 Ion transport protein N-terminal Spore_YhcN_YlaJ PF09580.5 ETN99944.1 - 0.00026 21.1 6.3 0.00031 20.8 4.4 1.2 1 0 0 1 1 1 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF3384 PF11864.3 ETN99944.1 - 0.00059 18.4 5.9 0.00066 18.2 4.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) BDV_P24 PF06595.6 ETN99944.1 - 0.037 13.7 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 Borna disease virus P24 protein PPR_3 PF13812.1 ETN99944.1 - 0.095 13.0 0.0 0.77 10.1 0.0 2.3 2 0 0 2 2 2 0 Pentatricopeptide repeat domain Secretin_N_2 PF07655.8 ETN99944.1 - 0.16 12.4 18.9 0.39 11.1 13.1 1.7 1 0 0 1 1 1 0 Secretin N-terminal domain TPR_2 PF07719.12 ETN99944.1 - 0.17 11.8 2.8 0.31 11.0 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 ETN99944.1 - 0.36 11.0 2.9 2.3 8.4 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Menin PF05053.8 ETN99944.1 - 0.6 8.2 9.1 1.1 7.3 6.3 1.4 1 0 0 1 1 1 0 Menin Period_C PF12114.3 ETN99944.1 - 0.95 9.0 3.9 4.5 6.8 0.1 2.3 2 0 0 2 2 2 0 Period protein 2/3C-terminal region GCD14 PF08704.5 ETN99944.1 - 3.3 7.1 5.0 1.9 7.9 1.7 2.0 2 1 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit RP-C_C PF11800.3 ETN99944.1 - 9.3 5.8 8.0 16 5.1 5.5 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Peptidase_M18 PF02127.10 ETN99945.1 - 9e-07 27.7 0.0 1.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) DUF1972 PF09314.6 ETN99946.1 - 0.049 13.0 0.2 0.11 11.9 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1972) FtsX PF02687.16 ETN99946.1 - 1 9.1 11.0 0.18 11.5 2.9 2.1 2 0 0 2 2 2 0 FtsX-like permease family Na_Ca_ex PF01699.19 ETN99946.1 - 2 8.0 10.0 0.56 9.8 3.0 2.2 1 1 1 2 2 2 0 Sodium/calcium exchanger protein MarC PF01914.12 ETN99946.1 - 2.1 7.4 9.3 5.7 6.0 0.3 2.6 2 1 1 3 3 3 0 MarC family integral membrane protein SUR7 PF06687.7 ETN99946.1 - 9.8 5.6 12.0 0.22 11.0 2.7 2.0 1 1 0 2 2 2 0 SUR7/PalI family WD40_alt PF14077.1 ETN99948.1 - 0.037 13.6 0.0 0.097 12.3 0.0 1.7 1 0 0 1 1 1 0 Alternative WD40 repeat motif IMPDH PF00478.20 ETN99950.1 - 3.5e-35 121.5 0.5 4.2e-35 121.2 0.4 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain DHHW PF14286.1 ETN99951.1 - 0.056 12.7 0.1 0.073 12.3 0.0 1.1 1 0 0 1 1 1 0 DHHW protein Pex14_N PF04695.8 ETN99951.1 - 0.067 13.2 0.2 0.18 11.8 0.1 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RVT_3 PF13456.1 ETN99953.1 - 0.021 14.5 0.5 0.031 14.0 0.3 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like LOH1CR12 PF10158.4 ETN99953.1 - 0.054 13.2 1.0 0.07 12.9 0.7 1.2 1 0 0 1 1 1 0 Tumour suppressor protein Perilipin PF03036.11 ETN99953.1 - 0.068 11.9 0.1 0.069 11.9 0.1 1.0 1 0 0 1 1 1 0 Perilipin family zf-C3HC4_2 PF13923.1 ETN99955.1 - 0.0095 15.9 1.3 0.14 12.2 0.9 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Lac_bphage_repr PF06543.7 ETN99957.1 - 0.084 12.4 4.3 0.21 11.1 3.0 1.7 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor CCDC-167 PF15188.1 ETN99957.1 - 0.7 9.8 8.1 4.6 7.2 0.4 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF2140 PF09911.4 ETN99962.1 - 0.0095 15.1 5.9 0.04 13.1 0.4 2.3 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2140) KRTDAP PF15200.1 ETN99962.1 - 2.3 8.0 6.1 0.64 9.8 0.6 2.3 2 0 0 2 2 2 0 Keratinocyte differentiation-associated Choline_sulf_C PF12411.3 ETN99963.1 - 0.063 13.1 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Choline sulfatase enzyme C terminal WD40 PF00400.27 ETN99965.1 - 3.7e-28 96.3 5.8 1.9e-11 43.3 0.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat PD40 PF07676.7 ETN99965.1 - 0.31 10.7 3.1 11 5.8 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Protamine_P2 PF00841.14 ETN99966.1 - 0.12 12.8 1.1 0.17 12.4 0.7 1.2 1 0 0 1 1 1 0 Sperm histone P2 Stig1 PF04885.8 ETN99966.1 - 0.14 12.3 3.8 0.15 12.2 2.6 1.0 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 DUF2347 PF09804.4 ETN99967.1 - 0.005 16.1 0.3 0.0058 15.9 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Exo_endo_phos_2 PF14529.1 ETN99967.1 - 0.047 13.2 1.5 5.9 6.5 0.2 2.5 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase Viral_Beta_CD PF04530.7 ETN99968.1 - 0.038 14.1 0.9 0.64 10.1 0.1 2.2 2 0 0 2 2 2 0 Viral Beta C/D like family GPS PF01825.16 ETN99969.1 - 0.0002 21.4 4.3 0.00026 21.0 1.9 2.0 2 0 0 2 2 2 1 Latrophilin/CL-1-like GPS domain CUE PF02845.11 ETN99970.1 - 0.02 14.3 0.1 0.045 13.2 0.1 1.5 1 0 0 1 1 1 0 CUE domain DUF106 PF01956.11 ETN99970.1 - 0.093 12.2 0.3 0.12 11.9 0.2 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 PI3_PI4_kinase PF00454.22 ETN99970.1 - 0.1 12.0 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase TPR_12 PF13424.1 ETN99971.1 - 3.1e-12 46.2 0.4 4.1e-05 23.4 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETN99971.1 - 1.4e-08 34.2 0.6 4.4e-08 32.6 0.2 2.1 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 ETN99971.1 - 2.4e-07 30.1 0.3 0.016 15.1 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETN99971.1 - 6.9e-07 28.6 1.8 0.0013 18.2 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETN99971.1 - 1.5e-05 24.3 6.2 0.048 13.4 1.1 3.3 3 0 0 3 3 2 2 Tetratricopeptide repeat Apc3 PF12895.2 ETN99971.1 - 5.6e-05 23.2 2.4 0.0042 17.1 0.6 2.8 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 ETN99971.1 - 0.0018 17.9 0.2 4.1 7.4 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat Peptidase_C14 PF00656.17 ETN99971.1 - 0.004 16.8 2.2 0.2 11.3 0.2 2.5 1 1 0 2 2 2 1 Caspase domain TPR_10 PF13374.1 ETN99971.1 - 0.015 15.2 0.0 0.83 9.6 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 ETN99971.1 - 0.028 14.6 0.1 13 6.2 0.0 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETN99971.1 - 0.17 12.2 0.3 6.6 7.1 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETN99971.1 - 0.33 10.8 3.6 13 5.7 0.2 2.9 3 0 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat Kelch_1 PF01344.20 ETN99972.1 - 1.9e-09 36.9 4.1 5e-06 25.9 0.4 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETN99972.1 - 3.9e-08 32.9 0.4 0.0018 17.9 0.0 3.8 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETN99972.1 - 7.3e-08 32.1 0.2 0.034 14.0 0.2 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETN99972.1 - 9.5e-08 31.9 4.1 0.00063 19.8 0.6 4.4 4 1 1 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETN99972.1 - 6.5e-05 22.5 2.7 0.016 14.9 0.1 4.2 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.1 ETN99972.1 - 0.0016 18.5 0.3 0.26 11.5 0.0 3.3 3 0 0 3 3 3 1 Galactose oxidase, central domain RPEL PF02755.10 ETN99973.1 - 1.3e-07 30.7 32.4 0.0004 19.6 0.4 9.4 10 0 0 10 10 10 4 RPEL repeat DUF2294 PF10057.4 ETN99973.1 - 0.061 12.9 1.3 0.9 9.2 0.1 3.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2294) DUF2203 PF09969.4 ETN99973.1 - 1.5 9.0 0.0 1.5 9.0 0.0 5.2 3 1 1 5 5 5 0 Uncharacterized conserved protein (DUF2203) T2SF PF00482.18 ETN99974.1 - 0.017 15.0 3.1 1.1 9.1 0.0 3.2 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein F DUF1216 PF06746.6 ETN99974.1 - 0.022 14.5 11.3 0.34 10.6 2.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1216) Sigma_reg_C PF13791.1 ETN99974.1 - 0.026 14.5 0.6 0.026 14.5 0.4 2.1 2 0 0 2 2 2 0 Sigma factor regulator C-terminal Reo_sigmaC PF04582.7 ETN99974.1 - 0.076 12.1 2.4 1 8.5 0.6 2.5 2 1 0 2 2 2 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 ETN99974.1 - 1.5 8.6 13.6 0.094 12.5 0.6 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) AAA_25 PF13481.1 ETN99974.1 - 2.3 7.5 4.7 0.99 8.7 0.2 2.6 3 0 0 3 3 3 0 AAA domain DUF4208 PF13907.1 ETN99974.1 - 3.9 7.7 22.9 1 9.6 0.1 4.6 3 1 0 5 5 5 0 Domain of unknown function (DUF4208) Pkinase PF00069.20 ETN99975.1 - 4.4e-67 225.9 0.7 4.4e-67 225.9 0.5 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETN99975.1 - 4.9e-32 111.0 0.3 4.9e-32 111.0 0.2 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Dyp_perox PF04261.7 ETN99975.1 - 0.032 12.9 0.0 0.064 11.9 0.0 1.5 1 0 0 1 1 1 0 Dyp-type peroxidase family GDI PF00996.13 ETN99976.1 - 2.3e-140 467.7 1.3 4.7e-107 358.0 0.0 2.1 1 1 1 2 2 2 2 GDP dissociation inhibitor PulG PF11773.3 ETN99977.1 - 0.14 11.8 3.8 0.48 10.1 0.0 2.7 2 1 0 2 2 2 0 Type II secretory pathway pseudopilin MlrC_C PF07171.7 ETN99978.1 - 0.048 13.2 0.1 0.073 12.6 0.1 1.3 1 0 0 1 1 1 0 MlrC C-terminus SeleniumBinding PF11524.3 ETN99978.1 - 0.55 10.3 2.5 1.3 9.1 0.1 2.6 1 1 1 2 2 2 0 Selenium binding protein WD40 PF00400.27 ETN99979.1 - 3e-06 26.8 0.4 5.7e-06 25.9 0.2 1.5 1 0 0 1 1 1 1 WD domain, G-beta repeat Hus1 PF04005.7 ETN99979.1 - 0.081 11.8 0.6 0.11 11.3 0.4 1.2 1 0 0 1 1 1 0 Hus1-like protein Rhabdo_ncap PF00945.13 ETN99979.1 - 0.5 8.9 2.8 0.64 8.5 1.9 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Inhibitor_I71 PF12628.2 ETN99979.1 - 2.1 8.0 7.3 2.5 7.7 3.7 1.9 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor PBP1_TM PF14812.1 ETN99979.1 - 3 8.2 13.5 5.3 7.4 9.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4455 PF14643.1 ETN99980.1 - 0.0034 16.0 8.0 0.0047 15.6 5.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) DASH_Dam1 PF08653.5 ETN99980.1 - 0.038 13.7 0.2 0.1 12.3 0.1 1.8 1 0 0 1 1 1 0 DASH complex subunit Dam1 Fib_alpha PF08702.5 ETN99980.1 - 0.24 11.5 13.6 0.42 10.7 9.3 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF148 PF02520.12 ETN99980.1 - 0.43 10.3 11.1 1.5 8.6 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function DUF148 DUF745 PF05335.8 ETN99980.1 - 0.92 8.9 6.2 0.57 9.6 2.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF342 PF03961.8 ETN99980.1 - 6.6 5.0 12.9 5.8 5.2 8.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) U-box PF04564.10 ETN99982.1 - 5.9e-11 42.1 0.0 2.6e-10 40.1 0.0 2.2 1 1 0 1 1 1 1 U-box domain LOH1CR12 PF10158.4 ETN99982.1 - 0.56 9.9 8.5 1.1 8.9 4.0 2.4 1 1 0 2 2 2 0 Tumour suppressor protein DUF948 PF06103.6 ETN99982.1 - 1.9 8.3 7.6 0.49 10.2 0.3 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) EpoR_lig-bind PF09067.5 ETN99983.1 - 0.011 15.6 1.0 0.02 14.8 0.5 1.5 1 1 0 1 1 1 0 Erythropoietin receptor, ligand binding FAM183 PF14886.1 ETN99984.1 - 0.098 13.1 2.0 0.25 11.8 0.8 2.1 2 0 0 2 2 2 0 FAM183A and FAM183B related DUF2011 PF09428.5 ETN99985.1 - 0.0046 16.8 1.2 0.0046 16.8 0.9 1.5 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF2011) Casc1 PF12366.3 ETN99985.1 - 0.047 13.1 2.2 0.059 12.8 1.5 1.0 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 DUF2365 PF10157.4 ETN99986.1 - 0.085 12.7 1.0 0.39 10.5 0.1 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2365) DUF1548 PF07579.6 ETN99986.1 - 0.086 12.9 3.8 0.67 10.0 0.0 2.8 1 1 0 2 2 2 0 Domain of Unknown Function (DUF1548) HATPase_c_5 PF14501.1 ETN99987.1 - 0.036 13.7 0.2 0.036 13.7 0.2 2.3 2 1 0 2 2 2 0 GHKL domain Daxx PF03344.10 ETN99987.1 - 0.36 9.2 15.3 0.43 8.9 10.6 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 ETN99987.1 - 2.3 6.1 19.4 4.6 5.1 13.5 1.5 1 1 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 ETN99987.1 - 2.4 5.7 14.7 3.1 5.3 10.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Tom37_C PF11801.3 ETN99987.1 - 7.3 6.4 8.3 0.98 9.2 1.9 2.0 1 1 1 2 2 2 0 Tom37 C-terminal domain Daxx PF03344.10 ETN99988.1 - 1.1 7.6 31.5 1.4 7.3 21.8 1.0 1 0 0 1 1 1 0 Daxx Family RNA_pol_Rpb1_5 PF04998.12 ETN99988.1 - 6.7 5.8 10.7 8.6 5.5 7.4 1.3 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 5 TPR_12 PF13424.1 ETN99989.1 - 9.7e-31 105.5 2.1 1.1e-09 38.0 0.1 4.4 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETN99989.1 - 2.7e-13 49.3 16.1 6.1e-06 25.7 1.8 3.6 3 1 0 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETN99989.1 - 1.1e-12 46.9 29.2 0.00088 18.7 0.7 5.8 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETN99989.1 - 5.1e-12 44.7 15.5 0.0045 16.7 0.3 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETN99989.1 - 1.1e-09 37.3 5.9 0.03 14.0 0.0 4.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETN99989.1 - 1.2e-08 34.0 30.9 0.0082 15.8 0.9 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETN99989.1 - 5.9e-08 32.3 0.0 0.04 13.8 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETN99989.1 - 0.0014 18.9 4.4 17 6.1 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.7 ETN99989.1 - 0.004 16.9 14.8 0.057 13.2 0.5 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 ETN99989.1 - 0.017 15.2 13.0 0.33 11.0 3.0 3.4 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 ETN99989.1 - 0.026 15.1 0.0 46 5.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETN99989.1 - 0.033 14.8 0.0 13 6.6 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF725 PF05267.7 ETN99989.1 - 0.043 13.7 0.1 0.28 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF725) SHNi-TPR PF10516.4 ETN99989.1 - 0.11 11.7 0.1 7.3 5.9 0.0 3.0 3 0 0 3 3 3 0 SHNi-TPR TPR_17 PF13431.1 ETN99989.1 - 0.15 12.3 13.5 0.71 10.2 0.1 5.1 4 2 1 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 ETN99989.1 - 0.44 10.4 14.3 1.4 8.8 0.3 3.8 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain SNAP PF14938.1 ETN99989.1 - 0.69 9.0 10.3 2.1 7.4 0.1 3.5 3 1 0 4 4 4 0 Soluble NSF attachment protein, SNAP Fis1_TPR_C PF14853.1 ETN99989.1 - 7 6.6 9.7 31 4.5 0.1 4.0 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat DUF912 PF06024.7 ETN99991.1 - 0.42 10.6 7.7 0.18 11.8 0.8 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) POX PF07526.6 ETN99991.1 - 0.63 10.2 4.4 1.1 9.5 0.3 2.1 2 0 0 2 2 2 0 Associated with HOX Vma12 PF11712.3 ETN99991.1 - 1.6 8.4 6.1 0.2 11.3 1.3 1.6 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Peptidase_S49_N PF08496.5 ETN99991.1 - 2.5 7.8 10.6 0.36 10.6 3.1 2.0 1 1 1 2 2 2 0 Peptidase family S49 N-terminal Gp49 PF05973.9 ETN99992.1 - 0.024 14.6 0.0 0.081 12.9 0.0 1.9 2 0 0 2 2 2 0 Phage derived protein Gp49-like (DUF891) RIC1 PF07064.8 ETN99993.1 - 0.028 13.8 0.2 0.041 13.3 0.2 1.3 1 0 0 1 1 1 0 RIC1 QCR10 PF09796.4 ETN99993.1 - 0.097 12.3 0.2 0.29 10.8 0.2 1.8 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Peptidase_S49_N PF08496.5 ETN99993.1 - 1.3 8.8 7.3 0.86 9.3 1.2 2.8 3 0 0 3 3 3 0 Peptidase family S49 N-terminal Cnd3 PF12719.2 ETN99994.1 - 0.037 13.0 0.1 0.054 12.4 0.1 1.3 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain LRR_6 PF13516.1 ETN99994.1 - 1.1 9.5 6.4 1.9 8.7 0.2 4.1 4 0 0 4 4 4 0 Leucine Rich repeat LRR_4 PF12799.2 ETN99994.1 - 2.1 8.0 7.7 0.76 9.4 0.8 3.0 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Herpes_pp85 PF04637.7 ETN99995.1 - 0.075 11.3 0.7 0.09 11.0 0.5 1.0 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) CM_1 PF07736.6 ETN99995.1 - 0.1 12.6 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Chorismate mutase type I PCMT PF01135.14 ETN99996.1 - 0.033 13.7 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Helicase_Sgs1 PF11408.3 ETN99996.1 - 0.79 9.5 5.9 1.4 8.7 3.8 1.6 1 1 0 1 1 1 0 Sgs1 RecQ helicase Ras PF00071.17 ETN99997.1 - 8.2e-08 31.8 0.1 1.2e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETN99997.1 - 2.2e-05 24.9 0.0 3.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein DUF2207 PF09972.4 ETN99997.1 - 0.063 11.8 1.6 0.068 11.7 1.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Arch_ATPase PF01637.13 ETN99997.1 - 0.09 12.4 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase Miro PF08477.8 ETN99998.1 - 0.013 16.0 1.6 0.042 14.3 1.1 1.8 1 1 0 1 1 1 0 Miro-like protein Dicty_REP PF05086.7 ETN99998.1 - 0.081 10.6 3.8 0.079 10.7 2.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TMEM154 PF15102.1 ETN99998.1 - 0.34 10.6 10.3 0.5 10.0 7.1 1.2 1 0 0 1 1 1 0 TMEM154 protein family DUF3439 PF11921.3 ETN99998.1 - 6.9 6.4 21.8 13 5.5 15.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 ETN99998.1 - 8.9 6.0 26.0 14 5.4 18.0 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein GDI PF00996.13 ETN99999.1 - 2.5e-16 59.0 0.3 3.2e-16 58.7 0.2 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor CDC45 PF02724.9 ETN99999.1 - 0.1 10.6 8.0 0.11 10.4 5.6 1.0 1 0 0 1 1 1 0 CDC45-like protein P30 PF07390.6 ETN99999.1 - 0.75 9.2 7.6 0.96 8.9 5.2 1.1 1 0 0 1 1 1 0 Mycoplasma P30 protein GEMIN8 PF15348.1 ETN99999.1 - 0.8 9.7 9.8 1.2 9.1 6.8 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Daxx PF03344.10 ETN99999.1 - 0.94 7.8 13.4 1.2 7.5 9.3 1.2 1 0 0 1 1 1 0 Daxx Family BTV_NS2 PF04514.7 ETN99999.1 - 1.9 7.2 9.8 2.6 6.8 6.8 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 WD40 PF00400.27 ETO00004.1 - 3e-36 121.9 13.9 9.1e-11 41.2 0.0 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO00004.1 - 9.6e-09 33.9 4.5 5.2e-05 21.5 0.8 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 DUF3373 PF11853.3 ETO00004.1 - 0.0028 16.2 4.0 0.0035 15.9 2.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3373) AP4E_app_platf PF14807.1 ETO00004.1 - 0.093 12.9 2.0 0.18 12.0 1.4 1.4 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform DUF3584 PF12128.3 ETO00004.1 - 0.094 10.0 8.3 0.11 9.8 5.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Flu_B_M2 PF04772.7 ETO00004.1 - 0.17 11.9 5.4 0.29 11.2 3.7 1.4 1 0 0 1 1 1 0 Influenza B matrix protein 2 (BM2) HapK PF11639.3 ETO00004.1 - 2.2 8.9 4.6 39 4.9 0.1 3.4 3 1 1 4 4 4 0 REDY-like protein HapK DUF678 PF05077.7 ETO00006.1 - 0.058 13.3 2.7 0.12 12.3 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF678) Sigma70_ner PF04546.8 ETO00007.1 - 0.095 12.3 0.3 0.17 11.5 0.2 1.5 1 1 0 1 1 1 0 Sigma-70, non-essential region TPR_12 PF13424.1 ETO00008.1 - 1.2e-51 172.5 8.1 9.5e-19 67.1 0.1 3.5 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO00008.1 - 4.1e-38 128.8 30.8 5.2e-12 45.2 0.3 3.6 1 1 4 5 5 5 5 TPR repeat TPR_1 PF00515.23 ETO00008.1 - 3.8e-27 92.7 22.2 5e-08 32.2 0.3 5.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO00008.1 - 7.4e-26 87.9 11.3 1.2e-06 27.9 0.1 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO00008.1 - 5.1e-24 82.1 3.3 2.9e-05 23.5 0.0 6.0 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO00008.1 - 1.4e-22 77.7 27.7 6e-06 25.6 0.1 5.7 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO00008.1 - 1.1e-14 53.7 0.0 0.01 15.7 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_6 PF13174.1 ETO00008.1 - 5.7e-09 35.8 3.5 1.1 9.8 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO00008.1 - 5.3e-08 32.8 0.0 3.4 8.5 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO00008.1 - 3.3e-06 27.1 16.2 0.00032 20.7 4.3 3.2 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO00008.1 - 4.1e-06 27.0 0.3 0.085 13.2 0.0 3.6 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO00008.1 - 4.5e-06 26.4 3.7 1.5 9.1 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO00008.1 - 5.6e-06 26.8 0.0 0.54 11.0 0.0 4.1 3 2 1 4 4 4 2 Tetratricopeptide repeat SNAP PF14938.1 ETO00008.1 - 1.5e-05 24.3 6.5 0.00023 20.3 0.9 2.8 1 1 1 2 2 2 1 Soluble NSF attachment protein, SNAP SHNi-TPR PF10516.4 ETO00008.1 - 0.00035 19.7 0.4 0.17 11.1 0.0 4.0 4 0 0 4 4 4 1 SHNi-TPR TPR_3 PF07720.7 ETO00008.1 - 0.011 15.5 18.2 1.7 8.5 0.4 5.9 5 1 0 5 5 5 0 Tetratricopeptide repeat Sel1 PF08238.7 ETO00008.1 - 0.031 14.9 3.5 11 6.8 0.3 3.6 3 0 0 3 3 3 0 Sel1 repeat DDE_3 PF13358.1 ETO00008.1 - 0.039 13.7 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease PPR PF01535.15 ETO00008.1 - 0.11 12.4 9.0 21 5.3 0.0 5.7 6 0 0 6 6 5 0 PPR repeat MIT PF04212.13 ETO00008.1 - 0.3 10.9 8.7 14 5.6 0.1 5.1 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain tRNA-synt_1d PF00750.14 ETO00009.1 - 0.0088 14.8 0.0 0.0095 14.7 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (R) DUF1779 PF08680.5 ETO00009.1 - 0.053 13.3 1.0 0.056 13.3 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1779) She9_MDM33 PF05546.6 ETO00011.1 - 0.00076 19.0 7.4 0.00097 18.7 5.1 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family GAS PF13851.1 ETO00011.1 - 0.00092 18.4 14.1 0.0016 17.6 9.8 1.3 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding CENP-Q PF13094.1 ETO00011.1 - 0.002 18.2 6.1 0.0022 18.0 4.2 1.1 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit OmpH PF03938.9 ETO00011.1 - 0.016 15.1 13.5 0.019 14.8 9.3 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Orbi_VP5 PF00901.12 ETO00011.1 - 0.02 13.1 4.4 0.021 13.0 3.0 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 AAA_27 PF13514.1 ETO00011.1 - 0.027 12.1 5.6 0.029 12.0 3.9 1.0 1 0 0 1 1 1 0 AAA domain HAUS5 PF14817.1 ETO00011.1 - 0.035 12.6 5.8 0.041 12.4 4.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Geminin PF07412.7 ETO00011.1 - 0.046 13.4 6.6 0.051 13.2 3.9 1.7 1 1 0 1 1 1 0 Geminin Spc7 PF08317.6 ETO00011.1 - 0.07 11.7 11.1 0.076 11.6 7.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Gln-synt_C PF00120.19 ETO00011.1 - 0.13 11.4 1.3 0.15 11.1 0.9 1.1 1 0 0 1 1 1 0 Glutamine synthetase, catalytic domain DUF641 PF04859.7 ETO00011.1 - 0.13 12.0 8.4 0.34 10.6 5.4 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF342 PF03961.8 ETO00011.1 - 0.22 9.9 8.5 0.24 9.7 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Atg14 PF10186.4 ETO00011.1 - 0.27 10.1 9.9 0.33 9.8 6.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HSCB_C PF07743.8 ETO00011.1 - 0.29 11.6 5.3 0.39 11.2 1.1 2.2 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain DUF2098 PF09871.4 ETO00011.1 - 0.33 10.8 6.3 0.45 10.4 4.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) IncA PF04156.9 ETO00011.1 - 0.35 10.4 11.0 0.41 10.2 7.6 1.1 1 0 0 1 1 1 0 IncA protein Bap31 PF05529.7 ETO00011.1 - 0.49 9.8 8.6 0.39 10.1 5.0 1.6 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like PhoU PF01895.14 ETO00011.1 - 0.66 10.4 3.7 0.57 10.6 1.9 1.4 1 1 0 1 1 1 0 PhoU domain ISG65-75 PF11727.3 ETO00011.1 - 1.1 8.2 6.4 1.3 8.0 4.4 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein DivIVA PF05103.8 ETO00011.1 - 1.3 9.1 12.6 0.88 9.6 6.6 1.9 1 1 1 2 2 2 0 DivIVA protein DUF603 PF04645.7 ETO00011.1 - 1.4 8.8 9.7 3.3 7.6 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF603 TMPIT PF07851.8 ETO00011.1 - 1.6 7.7 10.2 1.7 7.6 7.1 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF4337 PF14235.1 ETO00011.1 - 3.1 7.5 7.3 4.3 7.1 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) TMF_DNA_bd PF12329.3 ETO00011.1 - 4.2 7.2 15.0 0.67 9.7 5.8 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Tnp_P_element PF12017.3 ETO00011.1 - 7.3 5.7 8.3 3.7 6.7 3.7 1.8 1 1 1 2 2 2 0 Transposase protein FKBP_C PF00254.23 ETO00012.1 - 2.7e-05 24.0 0.2 7.4e-05 22.6 0.1 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF305 PF03713.8 ETO00012.1 - 0.46 10.2 2.1 0.56 10.0 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF305) DUF1299 PF06975.6 ETO00012.1 - 6.3 6.7 12.9 0.56 10.1 5.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1299) DUF2004 PF09406.5 ETO00013.1 - 0.063 13.3 5.3 0.1 12.6 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2004) BBIP10 PF14777.1 ETO00013.1 - 0.11 11.8 2.3 11 5.4 0.0 2.2 2 0 0 2 2 2 0 Cilia BBSome complex subunit 10 DUF2288 PF10052.4 ETO00013.1 - 0.55 9.9 4.2 2.9 7.6 0.6 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF2288) Kelch_4 PF13418.1 ETO00014.1 - 2.4e-08 33.6 0.5 9.7e-08 31.6 0.0 2.2 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO00014.1 - 2.1e-07 30.8 0.9 2.8e-05 24.0 0.1 2.9 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.20 ETO00014.1 - 4.8e-07 29.2 0.7 5.7e-06 25.7 0.0 2.9 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 ETO00014.1 - 2.7e-05 23.7 0.2 0.00025 20.6 0.0 2.7 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 ETO00014.1 - 6.2e-05 23.0 0.0 0.00018 21.5 0.0 1.8 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO00014.1 - 0.0028 17.5 0.5 0.014 15.3 0.3 2.2 3 0 0 3 3 3 1 Kelch motif HSP90 PF00183.13 ETO00016.1 - 1.8e-64 218.0 10.0 3.5e-55 187.4 0.1 3.1 2 1 1 3 3 3 3 Hsp90 protein P21-Arc PF04062.9 ETO00017.1 - 2.7e-23 82.6 0.1 3.1e-23 82.4 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit P2_Phage_GpR PF06891.6 ETO00017.1 - 0.04 13.6 0.0 0.046 13.5 0.0 1.1 1 0 0 1 1 1 0 P2 phage tail completion protein R (GpR) DUF348 PF03990.9 ETO00018.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF348) RNA_pol_Rpb2_1 PF04563.10 ETO00018.1 - 0.31 9.9 1.6 0.74 8.7 0.4 1.7 1 1 1 2 2 2 0 RNA polymerase beta subunit DUF3137 PF11335.3 ETO00019.1 - 0.00064 19.4 0.0 0.00072 19.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3137) HEAT_2 PF13646.1 ETO00019.1 - 0.0024 18.1 0.0 0.0032 17.7 0.0 1.1 1 0 0 1 1 1 1 HEAT repeats HEAT PF02985.17 ETO00019.1 - 0.0034 17.3 0.1 0.35 11.0 0.0 2.7 3 0 0 3 3 3 1 HEAT repeat MATH PF00917.21 ETO00019.1 - 0.098 12.8 0.1 0.13 12.5 0.1 1.2 1 0 0 1 1 1 0 MATH domain DUF3973 PF13119.1 ETO00020.1 - 0.13 12.2 0.1 0.4 10.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3973) DEP PF00610.16 ETO00021.1 - 0.0043 16.7 0.0 0.014 15.1 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) WD40 PF00400.27 ETO00022.1 - 2.3e-33 112.8 16.8 5.5e-11 41.9 0.3 4.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO00022.1 - 9.4e-05 20.7 2.6 0.42 8.6 0.0 3.6 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Transcrip_act PF04949.8 ETO00022.1 - 0.064 12.8 0.0 0.17 11.5 0.0 1.7 1 1 0 2 2 2 0 Transcriptional activator DUF3388 PF11868.3 ETO00023.1 - 0.0096 15.0 0.1 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3388) SecA_DEAD PF07517.9 ETO00026.1 - 0.015 14.5 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain UvrD-helicase PF00580.16 ETO00026.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Dicty_REP PF05086.7 ETO00027.1 - 0.18 9.5 1.2 0.21 9.3 0.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein WD40 PF00400.27 ETO00030.1 - 1.1e-29 101.1 9.8 3.5e-13 48.8 0.7 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO00030.1 - 0.00038 18.7 2.2 0.74 7.8 0.1 3.0 2 1 0 3 3 3 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO00030.1 - 0.011 15.4 0.5 0.11 12.2 0.2 2.1 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Resistin PF06954.6 ETO00030.1 - 0.1 12.8 2.2 0.35 11.1 0.6 2.2 1 1 1 2 2 2 0 Resistin DDE_3 PF13358.1 ETO00031.1 - 8.1e-15 54.8 1.4 1.1e-14 54.4 0.7 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 ETO00031.1 - 4.5e-11 42.6 2.0 4.5e-11 42.6 1.4 1.8 1 1 0 1 1 1 1 Transposase FUR PF01475.14 ETO00031.1 - 0.0069 16.3 0.8 0.032 14.1 0.3 2.1 2 0 0 2 2 2 1 Ferric uptake regulator family DUF2551 PF10826.3 ETO00031.1 - 0.063 13.1 0.3 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2551) TGT_C2 PF14810.1 ETO00031.1 - 0.13 12.1 1.2 5.2 6.9 0.1 2.7 3 0 0 3 3 3 0 Patch-forming domain C2 of tRNA-guanine transglycosylase DUF676 PF05057.9 ETO00033.1 - 2.3e-11 43.4 0.1 3.7e-11 42.7 0.1 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) CPSF100_C PF13299.1 ETO00034.1 - 0.0059 16.8 0.7 0.0098 16.0 0.5 1.3 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal End_beta_propel PF12217.3 ETO00034.1 - 0.057 12.1 0.8 0.087 11.4 0.2 1.5 1 1 0 1 1 1 0 Catalytic beta propeller domain of bacteriophage endosialidase Gag_spuma PF03276.9 ETO00034.1 - 3.3 5.9 9.7 5.2 5.2 6.7 1.2 1 0 0 1 1 1 0 Spumavirus gag protein DUF912 PF06024.7 ETO00034.1 - 6.1 6.9 7.6 2.6 8.1 3.5 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) 7TM-7TMR_HD PF07698.6 ETO00035.1 - 0.077 12.4 1.4 0.45 9.9 0.3 2.0 1 1 1 2 2 2 0 7TM receptor with intracellular HD hydrolase Kelch_4 PF13418.1 ETO00037.1 - 1.7e-07 30.8 0.0 3.7e-05 23.3 0.0 2.8 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO00037.1 - 8.7e-06 25.1 2.1 3.7e-05 23.1 0.3 2.4 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 ETO00037.1 - 5e-05 23.2 2.2 0.0051 16.9 0.2 3.2 2 1 1 3 3 3 1 Kelch motif Kelch_3 PF13415.1 ETO00037.1 - 0.00086 19.3 0.1 0.006 16.7 0.0 2.3 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO00037.1 - 0.0019 18.1 0.2 0.099 12.6 0.2 2.8 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO00037.1 - 0.02 14.6 0.1 0.33 10.7 0.1 2.4 2 0 0 2 2 2 0 Kelch motif Fucose_iso_N1 PF07881.7 ETO00038.1 - 0.052 13.0 1.0 0.85 9.1 0.0 2.2 2 0 0 2 2 2 0 L-fucose isomerase, first N-terminal domain Spore_II_R PF09551.5 ETO00038.1 - 1.1 9.2 10.1 0.66 10.0 4.9 1.8 1 1 1 2 2 2 0 Stage II sporulation protein R (spore_II_R) FixO PF02433.10 ETO00038.1 - 1.5 8.1 6.9 2.4 7.4 4.4 1.5 1 1 1 2 2 2 0 Cytochrome C oxidase, mono-heme subunit/FixO Otopetrin PF03189.8 ETO00038.1 - 2.7 6.8 5.6 3.4 6.5 3.9 1.0 1 0 0 1 1 1 0 Otopetrin FAM176 PF14851.1 ETO00038.1 - 4.7 6.8 10.2 2.9 7.5 5.8 1.5 1 1 1 2 2 2 0 FAM176 family DUF4452 PF14618.1 ETO00039.1 - 0.033 13.9 3.8 0.05 13.4 1.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4452) RinB PF06116.7 ETO00043.1 - 0.05 13.2 0.2 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 Transcriptional activator RinB WD40 PF00400.27 ETO00044.1 - 4.1e-05 23.2 0.1 0.00012 21.8 0.1 1.8 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF4181 PF13789.1 ETO00044.1 - 0.19 11.6 7.2 0.25 11.2 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) WD40 PF00400.27 ETO00046.1 - 4.9e-20 70.6 7.4 8.7e-08 31.7 0.1 4.1 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO00046.1 - 1.6e-07 29.9 1.9 0.005 15.0 0.1 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO00047.1 - 3.4e-07 30.5 1.9 3.4e-07 30.5 1.3 3.2 4 1 0 4 4 4 1 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 ETO00047.1 - 0.0042 17.0 0.4 0.0042 17.0 0.3 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF4258 PF14076.1 ETO00047.1 - 0.061 13.3 0.1 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4258) DUF1644 PF07800.7 ETO00047.1 - 0.14 12.0 7.8 12 5.7 5.4 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) zf-TRAF PF02176.13 ETO00048.1 - 9.3e-05 22.7 2.2 9.3e-05 22.7 1.5 2.4 2 0 0 2 2 2 1 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 ETO00048.1 - 0.091 12.8 0.4 0.091 12.8 0.3 3.5 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) GTP_CH_N PF12471.3 ETO00049.1 - 7.1e-08 32.2 1.5 0.0025 17.4 0.2 3.5 3 1 0 3 3 3 2 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 ETO00049.1 - 0.00014 21.2 0.0 0.00022 20.5 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II ABC2_membrane_4 PF12730.2 ETO00049.1 - 0.0088 15.2 1.3 0.012 14.7 0.9 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ATP-synt_8 PF00895.15 ETO00049.1 - 0.01 16.0 5.5 0.17 12.0 1.4 2.6 2 0 0 2 2 2 0 ATP synthase protein 8 DUF3796 PF12676.2 ETO00049.1 - 6.3 7.0 15.5 0.15 12.3 2.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) ETRAMP PF09716.5 ETO00049.1 - 6.9 6.6 7.5 19 5.2 0.0 3.1 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Pkinase PF00069.20 ETO00050.1 - 1.4e-20 73.5 1.4 1.9e-19 69.8 0.9 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO00050.1 - 2.6e-05 23.4 0.1 0.011 14.7 0.1 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase DUF4197 PF13852.1 ETO00051.1 - 0.00069 19.2 0.4 0.0013 18.2 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4197) UPF0697 PF15117.1 ETO00051.1 - 0.033 13.9 0.2 0.033 13.9 0.2 2.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0697 DASH_Duo1 PF08651.5 ETO00051.1 - 1.5 8.4 12.0 1 8.9 4.1 2.8 2 1 0 2 2 2 0 DASH complex subunit Duo1 Occludin_ELL PF07303.8 ETO00051.1 - 3.9 8.2 8.6 5.1 7.8 1.1 2.9 2 1 0 2 2 2 0 Occludin homology domain DUF342 PF03961.8 ETO00051.1 - 4.8 5.4 6.3 0.9 7.8 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF342) HEAT_2 PF13646.1 ETO00053.1 - 6.5e-10 39.1 0.0 0.00071 19.8 0.0 3.8 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.17 ETO00053.1 - 9.1e-09 34.6 0.0 0.00034 20.4 0.0 5.4 7 0 0 7 7 5 1 HEAT repeat HEAT_EZ PF13513.1 ETO00053.1 - 1.6e-05 25.2 0.0 0.0051 17.2 0.0 3.9 3 1 1 4 4 4 1 HEAT-like repeat Cnd1 PF12717.2 ETO00053.1 - 3.2e-05 23.8 4.7 0.0037 17.1 0.0 3.3 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 ETO00053.1 - 0.00012 22.4 1.6 0.016 15.5 0.0 3.3 2 2 2 4 4 4 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 ETO00053.1 - 0.00096 17.5 4.3 0.013 13.8 0.1 2.2 1 1 1 2 2 2 2 Adaptin N terminal region DUF2435 PF10363.4 ETO00053.1 - 0.0021 17.8 0.1 0.14 12.0 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) DUF3554 PF12074.3 ETO00053.1 - 0.0033 16.9 1.7 0.097 12.0 0.1 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF3554) MOR2-PAG1_C PF14225.1 ETO00053.1 - 0.0056 16.4 1.1 5.6 6.6 0.2 3.1 2 1 1 3 3 3 1 Cell morphogenesis C-terminal ENTH PF01417.15 ETO00053.1 - 0.0064 16.3 3.8 6.7 6.6 0.1 3.5 2 1 1 3 3 3 2 ENTH domain IPK PF03770.11 ETO00053.1 - 0.0069 16.0 3.5 0.04 13.5 2.2 2.1 1 1 0 1 1 1 1 Inositol polyphosphate kinase SusD-like PF12741.2 ETO00053.1 - 0.011 14.3 0.5 1.3 7.5 0.0 3.1 2 2 1 4 4 4 0 Susd and RagB outer membrane lipoprotein CLASP_N PF12348.3 ETO00053.1 - 0.011 15.0 0.6 0.18 11.1 0.0 2.3 2 0 0 2 2 2 0 CLASP N terminal DUF1018 PF06252.7 ETO00053.1 - 0.012 16.1 1.8 5.6 7.5 0.0 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1018) MMS19_C PF12460.3 ETO00053.1 - 0.021 13.5 10.6 0.05 12.3 4.2 3.3 1 1 2 3 3 3 0 RNAPII transcription regulator C-terminal HEAT_PBS PF03130.11 ETO00053.1 - 0.064 13.7 0.0 3.6 8.3 0.0 3.6 4 1 0 4 4 3 0 PBS lyase HEAT-like repeat Imm16 PF15565.1 ETO00053.1 - 0.19 11.5 5.4 2.4 8.0 0.4 3.3 3 1 1 4 4 4 0 Immunity protein 16 RNA_binding PF01877.12 ETO00053.1 - 0.36 10.8 4.3 8.5 6.4 0.1 3.9 2 2 1 4 4 4 0 RNA binding DUF3819 PF12842.2 ETO00054.1 - 0.014 15.1 0.3 0.015 15.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) Hep_59 PF07052.6 ETO00055.1 - 0.016 15.5 0.2 0.016 15.5 0.1 2.1 2 1 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 LMF1 PF06762.9 ETO00056.1 - 0.022 13.5 0.1 0.029 13.1 0.1 1.2 1 0 0 1 1 1 0 Lipase maturation factor Imm8 PF15560.1 ETO00056.1 - 2.9 7.5 8.5 22 4.7 5.9 2.0 1 1 0 1 1 1 0 Immunity protein 8 PaaX_C PF08223.6 ETO00057.1 - 0.09 12.4 0.1 0.095 12.3 0.1 1.2 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain WD40 PF00400.27 ETO00058.1 - 2.8e-05 23.8 0.6 0.00015 21.5 0.5 1.9 2 0 0 2 2 2 1 WD domain, G-beta repeat Beta_helix PF13229.1 ETO00058.1 - 0.013 15.2 1.4 0.015 15.0 0.9 1.1 1 0 0 1 1 1 0 Right handed beta helix region UpxZ PF06603.6 ETO00058.1 - 0.074 13.0 0.0 0.098 12.6 0.0 1.2 1 0 0 1 1 1 0 UpxZ family of transcription anti-terminator antagonists YppF PF14178.1 ETO00059.1 - 0.27 10.8 2.9 0.32 10.5 0.8 2.0 1 1 1 2 2 2 0 YppF-like protein HEAT PF02985.17 ETO00060.1 - 9.2e-09 34.6 0.0 0.00082 19.2 0.0 2.4 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.1 ETO00060.1 - 0.00026 21.2 0.0 0.0025 18.0 0.0 1.9 1 1 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.1 ETO00060.1 - 0.0045 17.4 0.0 0.011 16.2 0.0 1.6 1 1 1 2 2 2 1 HEAT-like repeat CLASP_N PF12348.3 ETO00060.1 - 0.026 13.9 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 CLASP N terminal CAAP1 PF15335.1 ETO00060.1 - 0.034 14.3 0.4 13 6.1 0.0 2.8 2 1 1 3 3 3 0 Caspase activity and apoptosis inhibitor 1 DUF3283 PF11686.3 ETO00060.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3283) NYD-SP28_assoc PF14775.1 ETO00062.1 - 0.033 13.8 0.9 0.085 12.5 0.6 1.7 1 0 0 1 1 1 0 Sperm tail C-terminal domain RHSP PF07999.6 ETO00062.1 - 0.074 11.6 0.9 0.08 11.5 0.6 1.0 1 0 0 1 1 1 0 Retrotransposon hot spot protein GCN5L1 PF06320.8 ETO00062.1 - 0.13 12.0 4.4 0.17 11.6 3.1 1.2 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) AAT PF03417.11 ETO00062.1 - 0.17 11.3 1.0 0.18 11.2 0.7 1.2 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase IncA PF04156.9 ETO00062.1 - 0.86 9.1 12.2 0.97 8.9 8.4 1.2 1 1 0 1 1 1 0 IncA protein TMCO5 PF14992.1 ETO00062.1 - 1.6 7.8 11.4 1.9 7.5 7.9 1.1 1 0 0 1 1 1 0 TMCO5 family TSC22 PF01166.13 ETO00062.1 - 1.9 8.5 5.0 0.48 10.4 1.3 1.7 2 0 0 2 2 2 0 TSC-22/dip/bun family FlxA PF14282.1 ETO00062.1 - 2 8.3 19.3 1.3 9.0 3.9 2.6 1 1 1 2 2 2 0 FlxA-like protein FimP PF09766.4 ETO00062.1 - 4.1 6.3 14.8 0.057 12.4 4.1 1.9 1 1 1 2 2 2 0 Fms-interacting protein APG6 PF04111.7 ETO00062.1 - 4.4 6.2 11.6 5.2 6.0 8.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 WD40 PF00400.27 ETO00063.1 - 0.0058 16.4 0.1 0.01 15.6 0.1 1.3 1 0 0 1 1 1 1 WD domain, G-beta repeat RtcR PF06956.6 ETO00064.1 - 0.074 12.3 0.1 0.074 12.3 0.0 1.2 1 0 0 1 1 1 0 Regulator of RNA terminal phosphate cyclase DUF1474 PF07342.6 ETO00064.1 - 0.2 11.9 4.5 0.23 11.6 3.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1474) LRR_4 PF12799.2 ETO00064.1 - 0.33 10.6 5.7 0.13 11.9 0.9 2.2 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) DnaI_N PF07319.6 ETO00064.1 - 0.39 11.0 4.1 0.26 11.5 0.7 2.0 2 0 0 2 2 2 0 Primosomal protein DnaI N-terminus DUF4215 PF13948.1 ETO00064.1 - 0.39 10.9 4.5 0.53 10.5 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4215) Mmp37 PF09139.6 ETO00064.1 - 0.51 9.3 4.7 0.54 9.2 3.3 1.1 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 DUF1542 PF07564.6 ETO00064.1 - 9.8 6.2 7.8 0.92 9.5 2.0 1.8 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1542) Aminotran_1_2 PF00155.16 ETO00065.1 - 3.9e-22 78.7 0.0 4.5e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1987 PF09345.5 ETO00067.1 - 0.11 12.3 1.4 0.23 11.2 0.8 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1987) CcdB PF01845.12 ETO00068.1 - 0.053 13.4 0.1 0.58 10.1 0.0 2.1 1 1 1 2 2 2 0 CcdB protein DUF2058 PF09831.4 ETO00069.1 - 0.072 12.9 5.2 0.084 12.7 3.6 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Vfa1 PF08432.5 ETO00069.1 - 0.12 12.4 8.4 0.12 12.3 5.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 ICA69 PF04629.9 ETO00069.1 - 0.12 12.3 7.4 0.13 12.1 5.1 1.0 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain Menin PF05053.8 ETO00069.1 - 0.14 10.2 0.7 0.14 10.3 0.5 1.0 1 0 0 1 1 1 0 Menin Tubulin PF00091.20 ETO00069.1 - 0.14 11.9 2.6 0.16 11.8 1.8 1.0 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain YqfQ PF14181.1 ETO00069.1 - 0.14 12.1 7.0 0.15 12.0 4.8 1.1 1 0 0 1 1 1 0 YqfQ-like protein Otopetrin PF03189.8 ETO00069.1 - 0.25 10.2 0.8 0.25 10.3 0.6 1.0 1 0 0 1 1 1 0 Otopetrin CDC45 PF02724.9 ETO00069.1 - 0.56 8.1 6.2 0.53 8.2 4.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Pox_RNA_Pol_19 PF05320.7 ETO00069.1 - 1 9.0 7.1 1.2 8.8 4.9 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit POX PF07526.6 ETO00069.1 - 2 8.6 7.0 2.3 8.4 4.8 1.1 1 0 0 1 1 1 0 Associated with HOX Rtf2 PF04641.7 ETO00069.1 - 2.7 7.1 9.2 3.2 6.8 6.4 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger DUF1510 PF07423.6 ETO00069.1 - 3.5 6.9 13.1 4.1 6.7 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2413 PF10310.4 ETO00069.1 - 3.7 6.2 11.0 4.2 6.0 7.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) RP-C_C PF11800.3 ETO00069.1 - 5.9 6.5 6.7 6.3 6.4 4.6 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Sec62 PF03839.11 ETO00069.1 - 8.1 5.7 7.6 8.7 5.6 5.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 CobT PF06213.7 ETO00069.1 - 8.8 5.3 11.6 9.8 5.2 8.0 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Mito_carr PF00153.22 ETO00070.1 - 2.2e-07 30.4 0.4 0.00068 19.2 0.0 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF4366 PF14283.1 ETO00070.1 - 0.13 11.6 0.3 0.17 11.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) AAA_5 PF07728.9 ETO00072.1 - 1.4e-05 24.8 0.0 3.1e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 ETO00072.1 - 9.4e-05 22.6 0.0 0.0002 21.5 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 ETO00072.1 - 0.0002 21.6 0.0 0.00045 20.5 0.0 1.6 2 0 0 2 2 2 1 ABC transporter Miro PF08477.8 ETO00072.1 - 0.00066 20.1 0.0 0.0021 18.5 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein NACHT PF05729.7 ETO00072.1 - 0.0014 18.2 0.1 0.047 13.3 0.1 2.5 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETO00072.1 - 0.0014 18.7 0.2 0.0055 16.8 0.0 2.0 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 ETO00072.1 - 0.0033 16.6 0.0 0.0049 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 ETO00072.1 - 0.0047 16.6 0.2 0.018 14.7 0.2 1.9 1 1 0 1 1 1 1 Archaeal ATPase Sigma54_activ_2 PF14532.1 ETO00072.1 - 0.0055 16.7 0.0 0.012 15.7 0.0 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_17 PF13207.1 ETO00072.1 - 0.015 16.0 0.1 8 7.3 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 ETO00072.1 - 0.018 14.9 0.3 0.049 13.5 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.1 ETO00072.1 - 0.031 14.2 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETO00072.1 - 0.04 13.9 0.0 0.094 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 ETO00072.1 - 0.06 13.6 0.8 0.36 11.1 0.1 2.1 2 1 0 2 2 2 0 AAA domain AIG1 PF04548.11 ETO00072.1 - 0.076 12.1 0.3 4.6 6.2 0.0 2.4 2 0 0 2 2 2 0 AIG1 family RNA_helicase PF00910.17 ETO00072.1 - 0.077 13.1 0.0 0.19 11.8 0.0 1.9 1 1 0 1 1 1 0 RNA helicase PduV-EutP PF10662.4 ETO00072.1 - 0.086 12.3 0.1 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.21 ETO00072.1 - 0.12 11.8 0.0 0.31 10.4 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain ATP-synt_ab PF00006.20 ETO00072.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Troponin PF00992.15 ETO00072.1 - 0.67 10.0 4.5 3 7.9 0.3 2.2 2 0 0 2 2 2 0 Troponin SRPRB PF09439.5 ETO00072.1 - 0.68 9.1 4.7 3 7.0 0.1 3.0 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit NACHT PF05729.7 ETO00073.1 - 1.7e-08 34.3 0.0 1.8e-08 34.1 0.0 1.0 1 0 0 1 1 1 1 NACHT domain Nbs1_C PF08599.5 ETO00073.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 DNA damage repair protein Nbs1 WD40 PF00400.27 ETO00074.1 - 1e-48 161.5 15.3 4e-15 55.0 0.1 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO00074.1 - 5.5e-07 28.0 4.7 0.034 12.3 0.4 3.6 1 1 1 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO00074.1 - 9.1e-06 25.2 1.3 4.5e-05 23.0 0.9 1.9 1 1 0 1 1 1 1 PQQ-like domain AcetylCoA_hyd_C PF13336.1 ETO00074.1 - 0.00032 20.4 3.2 1.1 8.9 0.1 3.0 1 1 2 3 3 3 2 Acetyl-CoA hydrolase/transferase C-terminal domain PD40 PF07676.7 ETO00074.1 - 0.00065 19.3 2.2 6.1 6.6 0.0 3.4 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat DUF1513 PF07433.6 ETO00074.1 - 0.0012 17.7 0.5 0.67 8.7 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF1513) DUF727 PF05303.7 ETO00074.1 - 0.0013 18.4 0.1 10 5.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF727) SAND PF01342.16 ETO00074.1 - 0.0015 18.1 1.2 0.97 9.1 0.1 2.3 2 1 0 2 2 2 2 SAND domain Gmad1 PF10647.4 ETO00074.1 - 0.0017 17.8 0.1 0.0055 16.1 0.1 2.1 1 1 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Cytochrom_D1 PF02239.11 ETO00074.1 - 0.0022 16.3 0.5 0.3 9.3 0.1 2.3 1 1 2 3 3 3 2 Cytochrome D1 heme domain SoxZ PF08770.6 ETO00074.1 - 0.0065 15.8 0.0 18 4.8 0.0 3.1 3 0 0 3 3 3 0 Sulphur oxidation protein SoxZ DUF4221 PF13970.1 ETO00074.1 - 0.0084 15.4 0.5 0.066 12.5 0.1 1.9 1 1 1 2 2 2 2 Domain of unknown function (DUF4221) Me-amine-dh_H PF06433.6 ETO00074.1 - 0.045 12.3 0.0 1.2 7.7 0.0 2.2 1 1 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) Reg_prop PF07494.6 ETO00074.1 - 0.052 13.5 0.5 37 4.8 0.0 3.5 3 0 0 3 3 3 0 Two component regulator propeller Nbas_N PF15492.1 ETO00074.1 - 0.068 12.2 2.8 3.7 6.5 0.2 2.7 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal TolB_N PF04052.8 ETO00074.1 - 0.11 12.6 0.0 28 4.8 0.0 3.6 4 0 0 4 4 4 0 TolB amino-terminal domain USP7_C2 PF14533.1 ETO00074.1 - 0.15 11.4 0.1 1e+02 2.2 0.0 3.5 1 1 2 4 4 4 0 Ubiquitin-specific protease C-terminal Nucleoporin_N PF08801.6 ETO00074.1 - 0.2 10.3 12.5 5.4 5.6 3.8 3.4 1 1 2 3 3 3 0 Nup133 N terminal like NYD-SP28_assoc PF14775.1 ETO00074.1 - 0.25 11.0 0.9 75 3.1 0.0 3.7 4 0 0 4 4 4 0 Sperm tail C-terminal domain Proteasome_A_N PF10584.4 ETO00074.1 - 0.47 9.8 7.3 13 5.1 0.0 3.7 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Ribosomal_S7 PF00177.16 ETO00075.1 - 0.0039 16.7 0.2 0.0039 16.7 0.2 2.4 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e DUF1702 PF08012.6 ETO00075.1 - 0.053 12.1 0.1 0.081 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1702) WD40 PF00400.27 ETO00076.1 - 4e-43 143.7 17.0 2.4e-12 46.2 0.3 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO00076.1 - 9.9e-10 37.1 0.6 0.014 13.5 0.0 4.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO00076.1 - 0.00018 20.4 1.1 0.34 9.5 0.1 3.4 1 1 2 3 3 3 2 Nup133 N terminal like Kelch_6 PF13964.1 ETO00076.1 - 0.16 12.2 1.8 14 6.0 0.0 3.8 4 0 0 4 4 4 0 Kelch motif Ricin_B_lectin PF00652.17 ETO00076.1 - 0.35 10.8 3.1 0.71 9.9 0.5 2.4 2 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain ERF PF04404.7 ETO00078.1 - 0.051 13.1 5.5 0.17 11.4 3.9 1.8 2 0 0 2 2 2 0 ERF superfamily CDC45 PF02724.9 ETO00078.1 - 0.21 9.5 6.6 0.24 9.4 4.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.12 ETO00078.1 - 0.62 9.8 6.1 0.77 9.5 4.2 1.1 1 0 0 1 1 1 0 DDHD domain DUF2894 PF11445.3 ETO00078.1 - 0.63 10.2 5.7 0.8 9.9 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) Vfa1 PF08432.5 ETO00078.1 - 4.2 7.3 17.3 5.9 6.8 12.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Vps52 PF04129.7 ETO00079.1 - 6.2e-19 67.8 7.6 9.1e-19 67.3 5.2 1.2 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 ETO00079.1 - 3.9e-05 22.0 10.4 5.9e-05 21.4 7.2 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 Myosin_tail_1 PF01576.14 ETO00079.1 - 0.0045 14.7 8.5 0.0037 15.0 5.3 1.2 1 1 0 1 1 1 1 Myosin tail COG2 PF06148.6 ETO00079.1 - 0.013 15.3 7.7 0.034 13.9 5.3 1.8 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Cob_adeno_trans PF01923.13 ETO00079.1 - 0.02 14.7 2.1 0.031 14.0 0.7 1.6 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Carbpep_Y_N PF05388.6 ETO00079.1 - 0.035 14.2 0.4 0.066 13.3 0.3 1.5 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide MscS_porin PF12795.2 ETO00079.1 - 0.043 13.1 4.7 0.092 12.0 3.3 1.7 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF4201 PF13870.1 ETO00079.1 - 0.048 13.0 11.5 0.078 12.4 7.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF2452 PF10504.4 ETO00079.1 - 0.051 12.8 0.8 0.086 12.1 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2452) Laminin_II PF06009.7 ETO00079.1 - 0.055 13.2 7.6 0.47 10.2 0.9 2.2 1 1 1 2 2 2 0 Laminin Domain II DUF3153 PF11353.3 ETO00079.1 - 0.061 12.7 2.0 0.095 12.1 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3153) Wbp11 PF09429.5 ETO00079.1 - 0.12 12.4 3.5 0.14 12.1 0.1 2.5 1 1 1 2 2 2 0 WW domain binding protein 11 LUC7 PF03194.10 ETO00079.1 - 0.13 11.7 4.2 0.19 11.2 2.5 1.6 1 1 0 1 1 1 0 LUC7 N_terminus Ssu72 PF04722.8 ETO00079.1 - 0.13 11.5 4.2 0.23 10.7 2.9 1.5 1 1 0 1 1 1 0 Ssu72-like protein Reo_sigmaC PF04582.7 ETO00079.1 - 0.21 10.7 2.0 0.25 10.4 1.4 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF948 PF06103.6 ETO00079.1 - 0.42 10.4 4.6 0.16 11.8 0.7 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) YlbD_coat PF14071.1 ETO00079.1 - 0.6 10.1 9.8 4 7.5 0.4 2.7 1 1 2 3 3 3 0 Putative coat protein COG5 PF10392.4 ETO00079.1 - 0.87 9.5 8.8 0.85 9.5 5.1 1.7 1 1 1 2 2 2 0 Golgi transport complex subunit 5 IncA PF04156.9 ETO00079.1 - 1 8.9 9.6 1.3 8.5 6.3 1.4 1 1 0 1 1 1 0 IncA protein DUF1664 PF07889.7 ETO00079.1 - 1.2 8.9 7.0 1.1 9.0 2.8 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Syntaxin_2 PF14523.1 ETO00079.1 - 1.8 8.6 9.8 0.86 9.6 2.7 2.6 1 1 1 2 2 2 0 Syntaxin-like protein Noelin-1 PF12308.3 ETO00079.1 - 1.9 8.3 5.3 0.61 9.9 0.7 2.3 2 1 1 3 3 3 0 Neurogenesis glycoprotein OmpH PF03938.9 ETO00079.1 - 2.5 8.0 6.3 12 5.8 3.4 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Fib_alpha PF08702.5 ETO00079.1 - 3.2 7.8 10.4 1.7 8.7 3.7 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Ribosomal_L27e PF01777.13 ETO00081.1 - 0.2 11.8 0.2 0.2 11.8 0.1 2.3 2 1 0 2 2 2 0 Ribosomal L27e protein family Peptidase_S49_N PF08496.5 ETO00081.1 - 0.29 10.9 5.4 0.16 11.7 1.9 1.8 2 0 0 2 2 2 0 Peptidase family S49 N-terminal WD40 PF00400.27 ETO00082.1 - 2.1e-28 97.1 3.5 9e-13 47.5 0.0 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO00082.1 - 0.001 17.3 0.1 0.094 10.8 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Latarcin PF10279.4 ETO00083.1 - 9.7 6.4 7.7 2.8 8.2 3.4 1.5 2 0 0 2 2 2 0 Latarcin precursor DUF3292 PF11696.3 ETO00084.1 - 0.018 12.9 1.6 0.022 12.6 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) CysG_dimeriser PF10414.4 ETO00084.1 - 0.092 12.2 0.1 0.92 9.0 0.0 2.1 2 0 0 2 2 2 0 Sirohaem synthase dimerisation region NYD-SP28 PF14772.1 ETO00084.1 - 0.15 12.1 3.1 0.43 10.6 0.4 2.4 2 0 0 2 2 2 0 Sperm tail SspN PF08177.6 ETO00084.1 - 0.24 11.1 3.0 0.78 9.5 2.1 1.9 1 0 0 1 1 1 0 Small acid-soluble spore protein N family DUF1140 PF06600.6 ETO00084.1 - 1.2 9.2 6.8 0.45 10.6 2.1 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1140) AAA_5 PF07728.9 ETO00085.1 - 4.2e-13 49.2 0.1 4.5e-11 42.6 0.1 2.4 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 ETO00085.1 - 0.02 14.4 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 ETO00085.1 - 0.068 12.3 0.0 0.16 11.1 0.0 1.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SPOB_ab PF14682.1 ETO00086.1 - 0.011 15.4 0.7 0.019 14.7 0.5 1.5 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal WD40 PF00400.27 ETO00088.1 - 3e-26 90.3 0.6 3.3e-12 45.7 0.0 3.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO00088.1 - 0.00019 19.7 0.1 0.026 12.6 0.0 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO00088.1 - 0.0057 16.3 0.1 0.008 15.9 0.1 1.4 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 ETO00088.1 - 0.019 14.4 0.0 0.12 11.8 0.0 1.9 1 1 0 1 1 1 0 PQQ-like domain Nucleoporin_N PF08801.6 ETO00088.1 - 0.024 13.4 0.1 0.044 12.5 0.1 1.5 1 1 0 1 1 1 0 Nup133 N terminal like PQQ PF01011.16 ETO00088.1 - 0.094 12.2 0.0 28 4.4 0.0 2.9 3 0 0 3 3 3 0 PQQ enzyme repeat HALZ PF02183.13 ETO00090.1 - 0.00036 20.1 0.2 0.011 15.4 0.0 2.8 2 0 0 2 2 2 1 Homeobox associated leucine zipper Cbl_N PF02262.11 ETO00090.1 - 0.031 13.9 4.7 3.6 7.3 0.0 2.6 2 1 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 DUF2353 PF09789.4 ETO00090.1 - 0.042 13.1 4.7 0.065 12.4 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) DsrD PF08679.6 ETO00090.1 - 0.076 13.0 1.4 0.14 12.1 0.4 1.9 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) DUF1539 PF07560.6 ETO00090.1 - 0.16 11.8 5.1 0.12 12.2 0.9 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) Snapin_Pallidin PF14712.1 ETO00090.1 - 0.59 10.4 4.9 4.8 7.5 1.6 2.4 2 0 0 2 2 2 0 Snapin/Pallidin DUF972 PF06156.8 ETO00090.1 - 0.6 10.4 6.5 0.85 10.0 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF1870 PF08965.5 ETO00090.1 - 0.7 9.5 4.7 0.37 10.4 1.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1870) RelA_SpoT PF04607.12 ETO00091.1 - 0.0056 16.6 0.8 0.0081 16.1 0.1 1.5 2 0 0 2 2 2 1 Region found in RelA / SpoT proteins Sipho_Gp157 PF05565.6 ETO00091.1 - 0.084 12.4 4.8 2.5 7.6 1.3 2.1 1 1 1 2 2 2 0 Siphovirus Gp157 RNase_P_p30 PF01876.11 ETO00091.1 - 0.088 12.0 0.0 5.7 6.1 0.0 2.1 2 0 0 2 2 2 0 RNase P subunit p30 TTL PF03133.10 ETO00095.1 - 0.00094 18.1 0.1 0.0012 17.8 0.1 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATP_bind_1 PF03029.12 ETO00095.1 - 0.074 12.5 0.1 0.081 12.4 0.1 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein zf-C3HC4_2 PF13923.1 ETO00097.1 - 0.14 12.2 4.3 9.4 6.3 1.1 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Dsl1_C PF11989.3 ETO00099.1 - 0.0023 17.1 1.9 0.0031 16.7 1.3 1.1 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal PPR_2 PF13041.1 ETO00100.1 - 0.002 18.0 0.0 0.0035 17.2 0.0 1.3 1 0 0 1 1 1 1 PPR repeat family DUF1900 PF08954.6 ETO00100.1 - 0.0067 15.9 0.1 0.044 13.2 0.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1900) PPR PF01535.15 ETO00100.1 - 0.0074 16.2 0.1 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 PPR repeat YceI PF04264.8 ETO00100.1 - 0.038 13.9 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 YceI-like domain Peptidase_C80 PF11713.3 ETO00100.1 - 0.13 12.0 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Peptidase C80 family DUF2610 PF11020.3 ETO00102.1 - 0.017 14.9 0.6 0.029 14.1 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2610) DUF3609 PF12259.3 ETO00102.1 - 0.047 12.3 0.3 0.058 12.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) TPR_12 PF13424.1 ETO00104.1 - 3.6e-28 97.3 1.6 9e-15 54.3 0.2 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO00104.1 - 3.4e-14 52.1 0.0 2e-05 24.3 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO00104.1 - 2.7e-13 48.6 0.7 0.00064 19.3 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO00104.1 - 3.8e-13 48.8 3.3 6.7e-06 25.6 0.0 3.3 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 ETO00104.1 - 6.4e-13 47.5 6.4 0.00026 20.6 0.4 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO00104.1 - 2.2e-11 42.8 15.7 2.7e-06 26.7 0.7 4.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO00104.1 - 2.1e-10 39.5 11.2 3.4e-05 23.3 1.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO00104.1 - 2.1e-06 27.4 0.1 0.084 13.1 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO00104.1 - 2.2e-05 24.9 0.0 0.39 11.4 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO00104.1 - 3.8e-05 23.8 0.4 4.4 7.9 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO00104.1 - 0.018 15.1 1.9 0.38 10.9 0.6 3.4 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF2422 PF10337.4 ETO00104.1 - 0.067 11.9 3.6 0.02 13.6 0.6 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) DUF357 PF04010.8 ETO00104.1 - 0.39 10.4 4.7 8.7 6.1 0.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF357) WD40 PF00400.27 ETO00105.1 - 3.8e-39 131.1 6.5 2.7e-11 42.8 0.5 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO00105.1 - 4.2e-08 31.7 1.2 0.016 13.3 0.0 3.0 2 1 1 3 3 3 3 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO00105.1 - 4.7e-07 29.7 0.0 9.5e-05 22.1 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO00105.1 - 2e-05 24.1 1.6 1.5 8.6 0.0 4.3 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 ETO00105.1 - 3.1e-05 23.2 3.3 0.63 9.4 0.1 4.3 4 0 0 4 4 4 1 Proteasome subunit A N-terminal signature PQQ_2 PF13360.1 ETO00105.1 - 0.00031 20.3 0.4 0.0015 18.0 0.3 1.9 1 1 0 1 1 1 1 PQQ-like domain Str_synth PF03088.11 ETO00105.1 - 0.00086 19.2 0.0 0.94 9.5 0.0 3.3 2 1 1 3 3 3 1 Strictosidine synthase DUF3601 PF12208.3 ETO00105.1 - 0.011 15.6 0.0 2 8.3 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3601) DPPIV_N PF00930.16 ETO00105.1 - 0.018 13.6 0.0 1.6 7.2 0.0 2.7 1 1 2 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Cytochrom_D1 PF02239.11 ETO00105.1 - 0.06 11.6 0.0 16 3.6 0.0 2.8 1 1 2 3 3 3 0 Cytochrome D1 heme domain Lactonase PF10282.4 ETO00105.1 - 0.099 11.7 0.0 0.28 10.2 0.0 1.8 1 1 0 1 1 1 0 Lactonase, 7-bladed beta-propeller GspH PF12019.3 ETO00105.1 - 0.11 12.6 0.5 1.6 8.8 0.2 2.6 2 1 0 2 2 2 0 Type II transport protein GspH MCM PF00493.18 ETO00106.1 - 7.4e-51 172.8 0.4 3.4e-50 170.7 0.3 1.9 1 1 0 1 1 1 1 MCM2/3/5 family AAA_5 PF07728.9 ETO00106.1 - 6e-06 26.0 0.0 0.00016 21.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETO00106.1 - 0.00067 19.7 2.8 0.011 15.8 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 ETO00106.1 - 0.008 16.1 2.1 0.016 15.2 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.1 ETO00106.1 - 0.024 14.2 0.0 0.063 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 ETO00106.1 - 0.025 13.7 0.0 0.12 11.5 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 ETO00106.1 - 0.026 14.7 0.2 0.33 11.1 0.0 2.6 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 ETO00106.1 - 0.029 14.0 0.1 0.082 12.6 0.1 1.8 1 1 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 ETO00106.1 - 0.046 13.9 0.2 3.5 7.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Miro PF08477.8 ETO00106.1 - 0.068 13.6 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 ETO00106.1 - 0.59 10.4 2.4 1.6 8.9 0.0 2.7 2 1 1 3 3 3 0 ABC transporter AAA_18 PF13238.1 ETO00106.1 - 6 7.1 7.4 3.3 8.0 0.1 3.1 2 1 0 3 3 3 0 AAA domain EpsG PF14897.1 ETO00107.1 - 0.0026 16.7 8.3 0.0046 15.9 5.8 1.4 1 1 0 1 1 1 1 EpsG family 7TMR-DISM_7TM PF07695.6 ETO00107.1 - 0.015 14.9 7.8 0.021 14.4 5.4 1.3 1 1 0 1 1 1 0 7TM diverse intracellular signalling TMEM220 PF15071.1 ETO00107.1 - 0.074 13.4 2.8 0.24 11.8 0.9 2.0 2 0 0 2 2 2 0 Transmembrane family 220, helix Oxidored_q3 PF00499.15 ETO00107.1 - 0.16 11.7 7.2 0.046 13.4 2.5 2.0 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF3816 PF12822.2 ETO00107.1 - 2 8.2 9.4 3.1 7.6 6.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) SdpI PF13630.1 ETO00107.1 - 2.1 8.1 7.0 0.18 11.5 0.9 2.1 3 0 0 3 3 3 0 SdpI/YhfL protein family DUF4131 PF13567.1 ETO00107.1 - 2.2 7.6 11.4 0.076 12.4 1.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) PI3_PI4_kinase PF00454.22 ETO00108.1 - 3.4e-05 23.4 0.1 6.7e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase Peptidase_S10 PF00450.17 ETO00109.1 - 1.3e-58 199.1 11.5 3.1e-56 191.3 7.0 3.2 2 1 0 2 2 2 1 Serine carboxypeptidase SET_assoc PF11767.3 ETO00109.1 - 0.038 13.3 0.1 0.1 11.9 0.0 1.7 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated EF1G PF00647.14 ETO00109.1 - 0.13 11.9 2.1 1.2 8.8 0.1 3.1 3 0 0 3 3 3 0 Elongation factor 1 gamma, conserved domain CAP_GLY PF01302.20 ETO00110.1 - 6.3e-21 73.8 0.1 1.1e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 ETO00110.1 - 5.6e-13 48.9 0.6 1.4e-12 47.7 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin-like domain PNPase PF03726.9 ETO00110.1 - 1 9.6 3.7 1.8 8.8 2.6 1.3 1 0 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain WD40 PF00400.27 ETO00111.1 - 2.4e-29 100.1 6.2 7.2e-12 44.7 0.0 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO00111.1 - 6.2e-06 24.6 0.1 0.076 11.1 0.0 2.6 1 1 0 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO00111.1 - 0.0053 15.5 4.9 0.88 8.2 3.4 2.7 1 1 0 1 1 1 1 Nup133 N terminal like RPAP2_Rtr1 PF04181.8 ETO00111.1 - 0.19 11.8 2.4 7.4 6.7 0.2 2.5 3 0 0 3 3 3 0 Rtr1/RPAP2 family Peptidase_C14 PF00656.17 ETO00112.1 - 2.1e-11 44.0 0.2 2.2e-11 43.9 0.2 1.1 1 0 0 1 1 1 1 Caspase domain CO_dh PF02552.11 ETO00112.1 - 0.031 13.8 0.4 0.049 13.1 0.3 1.2 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Lysozyme_like PF13702.1 ETO00112.1 - 0.057 12.9 0.0 0.089 12.2 0.0 1.3 1 0 0 1 1 1 0 Lysozyme-like DUF1726 PF08351.6 ETO00112.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1726) JmjC PF02373.17 ETO00113.1 - 0.093 12.9 0.1 1.5 9.0 0.0 2.1 2 0 0 2 2 2 0 JmjC domain, hydroxylase PUB PF09409.5 ETO00114.1 - 0.0022 17.7 0.7 0.037 13.8 0.5 2.3 1 1 0 1 1 1 1 PUB domain DUF1064 PF06356.6 ETO00115.1 - 0.028 14.4 0.7 0.59 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1064) PIP5K PF01504.13 ETO00116.1 - 5e-54 183.0 1.2 1.2e-53 181.8 0.8 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 ETO00116.1 - 1e-27 96.9 0.0 2.1e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NACHT PF05729.7 ETO00117.1 - 0.00075 19.1 0.1 0.00092 18.9 0.1 1.2 1 0 0 1 1 1 1 NACHT domain p450 PF00067.17 ETO00118.1 - 1.9e-59 201.4 0.0 2.3e-59 201.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NACHT PF05729.7 ETO00119.1 - 0.019 14.6 0.1 0.068 12.8 0.0 1.9 2 0 0 2 2 2 0 NACHT domain FtsK_SpoIIIE PF01580.13 ETO00119.1 - 0.2 11.0 5.0 0.54 9.7 0.0 2.8 2 1 0 3 3 3 0 FtsK/SpoIIIE family Miro PF08477.8 ETO00119.1 - 1.2 9.6 0.0 1.2 9.6 0.0 3.6 4 1 0 4 4 4 0 Miro-like protein Glyco_transf_10 PF00852.14 ETO00122.1 - 0.0012 17.4 0.3 0.0016 17.0 0.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) DUF2981 PF11200.3 ETO00122.1 - 0.15 11.1 1.4 0.16 11.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) DSX_dimer PF08828.5 ETO00123.1 - 0.06 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Doublesex dimerisation domain Toxin_30 PF08117.6 ETO00123.1 - 0.096 12.7 6.1 0.17 11.9 4.2 1.3 1 0 0 1 1 1 0 Ptu family PUB PF09409.5 ETO00124.1 - 0.00016 21.3 1.0 0.0015 18.2 0.7 2.0 1 1 0 1 1 1 1 PUB domain Myosin_head PF00063.16 ETO00124.1 - 0.043 11.8 0.4 0.046 11.7 0.2 1.0 1 0 0 1 1 1 0 Myosin head (motor domain) Aph-1 PF06105.7 ETO00124.1 - 0.062 12.5 0.5 0.14 11.3 0.3 1.7 1 1 0 1 1 1 0 Aph-1 protein Prion PF00377.13 ETO00124.1 - 0.072 12.8 1.1 5.9 6.6 0.0 2.1 2 0 0 2 2 2 0 Prion/Doppel alpha-helical domain DUF4304 PF14137.1 ETO00124.1 - 0.19 11.8 0.2 0.19 11.8 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4304) Post_transc_reg PF13797.1 ETO00124.1 - 0.31 10.6 2.5 6 6.5 0.1 2.2 1 1 1 2 2 2 0 Post-transcriptional regulator Strumpellin PF10266.4 ETO00125.1 - 0.0025 15.3 2.8 0.0028 15.1 1.9 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin PTPS PF01242.14 ETO00125.1 - 0.11 12.1 0.1 0.13 11.9 0.1 1.1 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase DUF3744 PF12558.3 ETO00125.1 - 0.18 12.2 3.6 1.3 9.5 0.1 2.2 2 0 0 2 2 2 0 ATP-binding cassette cobalt transporter MIT PF04212.13 ETO00125.1 - 0.49 10.3 2.8 13 5.7 0.4 2.4 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain RNase_H2-Ydr279 PF09468.5 ETO00127.1 - 5.2 6.1 12.8 5.8 6.0 8.9 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Ribosom_S12_S23 PF00164.20 ETO00128.1 - 7.1e-35 119.0 4.3 4.2e-30 103.6 0.3 2.2 1 1 1 2 2 2 2 Ribosomal protein S12/S23 DUF4251 PF14059.1 ETO00129.1 - 0.067 13.0 0.7 0.15 11.8 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4251) Clostridium_P47 PF06597.6 ETO00131.1 - 0.015 13.8 0.1 0.02 13.4 0.1 1.1 1 0 0 1 1 1 0 Clostridium P-47 protein Phostensin PF13914.1 ETO00132.1 - 0.18 11.9 1.2 0.28 11.3 0.8 1.4 1 1 0 1 1 1 0 Phostensin PP1-binding and SH3-binding region DUF2956 PF11169.3 ETO00133.1 - 0.014 15.3 7.5 0.093 12.6 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) DUF3813 PF12758.2 ETO00133.1 - 0.1 12.7 0.8 0.22 11.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) DUF4405 PF14358.1 ETO00134.1 - 0.46 10.6 5.3 1.1 9.4 3.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4405) Binary_toxB PF03495.9 ETO00135.1 - 0.12 11.0 0.8 0.12 10.9 0.5 1.0 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA Exo_endo_phos_2 PF14529.1 ETO00136.1 - 3.7e-11 42.6 1.8 9e-11 41.4 0.2 2.5 1 1 1 2 2 2 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 ETO00136.1 - 0.00028 20.3 1.7 0.00034 20.0 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Lac_bphage_repr PF06543.7 ETO00138.1 - 0.0085 15.6 1.1 0.022 14.2 0.4 1.9 2 0 0 2 2 2 1 Lactococcus bacteriophage repressor Vps51 PF08700.6 ETO00138.1 - 0.14 12.0 3.3 1.4 8.8 0.4 2.2 2 0 0 2 2 2 0 Vps51/Vps67 DASH_Dad3 PF08656.5 ETO00138.1 - 0.27 10.9 2.6 0.23 11.1 0.3 2.1 2 1 0 2 2 2 0 DASH complex subunit Dad3 Snapin_Pallidin PF14712.1 ETO00138.1 - 1.1 9.5 9.0 0.45 10.8 1.3 2.2 1 1 0 2 2 2 0 Snapin/Pallidin G10 PF01125.12 ETO00138.1 - 1.2 8.7 4.0 5.4 6.5 0.2 2.1 2 0 0 2 2 2 0 G10 protein DUF2408 PF10303.4 ETO00138.1 - 3.4 7.7 8.4 48 4.0 5.8 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) FlxA PF14282.1 ETO00138.1 - 7.1 6.6 11.6 3.5 7.6 0.7 2.2 2 0 0 2 2 2 0 FlxA-like protein DUF3508 PF12018.3 ETO00139.1 - 0.028 13.4 0.3 0.028 13.4 0.2 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3508) WASH_WAHD PF11945.3 ETO00139.1 - 0.17 11.1 2.3 0.19 11.0 1.6 1.0 1 0 0 1 1 1 0 WAHD domain of WASH complex Sigma_reg_C PF13791.1 ETO00139.1 - 0.36 10.8 4.7 0.38 10.7 3.2 1.1 1 0 0 1 1 1 0 Sigma factor regulator C-terminal NDUF_B5 PF09781.4 ETO00139.1 - 2.4 7.3 5.7 0.17 11.1 0.6 1.5 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit TPR_11 PF13414.1 ETO00140.1 - 1.2e-27 95.3 34.8 6.7e-12 44.8 3.5 3.8 1 1 3 4 4 4 4 TPR repeat TPR_17 PF13431.1 ETO00140.1 - 4.4e-15 54.5 20.5 5.9e-05 22.9 1.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO00140.1 - 6.2e-13 48.1 8.1 0.013 16.0 0.0 4.3 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO00140.1 - 1.6e-11 44.5 15.8 2.5e-06 28.0 2.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO00140.1 - 1.4e-10 40.2 27.5 0.0036 17.0 0.3 5.8 5 3 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO00140.1 - 1.6e-10 40.1 25.5 0.0016 17.9 0.1 6.0 4 2 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO00140.1 - 3.4e-10 40.1 12.6 0.00027 21.2 1.1 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 ETO00140.1 - 7e-10 38.7 21.5 6.5e-06 25.9 4.7 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO00140.1 - 8.7e-10 37.6 18.7 0.0033 17.1 2.0 5.0 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO00140.1 - 2.4e-05 24.4 6.1 4.2 8.0 0.2 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETO00140.1 - 0.00041 20.1 5.2 0.0032 17.2 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO00140.1 - 0.00042 19.9 8.5 2.6 8.0 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat eIF-3c_N PF05470.7 ETO00140.1 - 0.0037 15.4 2.4 0.0043 15.2 1.7 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Fis1_TPR_C PF14853.1 ETO00140.1 - 0.024 14.4 5.2 0.22 11.4 0.1 3.2 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat MitMem_reg PF13012.1 ETO00140.1 - 0.075 13.1 0.8 0.18 11.8 0.2 1.9 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function Syd PF07348.7 ETO00140.1 - 0.11 11.8 1.0 0.15 11.3 0.1 1.6 2 0 0 2 2 2 0 Syd protein (SUKH-2) YkyA PF10368.4 ETO00140.1 - 9.6 5.4 9.2 0.38 10.0 0.8 2.1 1 1 0 2 2 2 0 Putative cell-wall binding lipoprotein mRNA_stabil PF13929.1 ETO00141.1 - 0.033 13.1 2.0 0.037 12.9 1.4 1.0 1 0 0 1 1 1 0 mRNA stabilisation Ribosomal_L6e PF01159.14 ETO00141.1 - 0.29 11.3 5.8 0.33 11.1 4.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L6e eIF3_p135 PF12807.2 ETO00141.1 - 1.2 9.0 4.9 1.4 8.8 3.4 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 Mucin PF01456.12 ETO00141.1 - 4.8 6.9 17.0 6.1 6.6 11.8 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2589 PF11655.3 ETO00142.1 - 0.087 12.9 1.5 0.16 12.0 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2589) Pkinase PF00069.20 ETO00143.1 - 1.7e-06 27.3 0.1 2.5e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO00143.1 - 0.0084 15.2 0.1 0.012 14.7 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2317 PF10079.4 ETO00146.1 - 0.0083 14.7 0.4 0.0088 14.7 0.3 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2317) DUF4468 PF14730.1 ETO00146.1 - 0.042 13.5 0.3 0.066 12.9 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4468) with TBP-like fold DUF1462 PF07315.6 ETO00146.1 - 0.051 13.5 0.1 0.069 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) DDE_Tnp_IS240 PF13610.1 ETO00146.1 - 0.087 12.7 1.2 0.29 11.1 0.8 1.8 1 1 0 1 1 1 0 DDE domain SAM_2 PF07647.12 ETO00147.1 - 2.2e-14 53.0 0.9 1.4e-09 37.6 0.2 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO00147.1 - 6.3e-12 45.4 0.6 4.9e-08 33.0 0.1 2.6 2 1 0 2 2 2 2 SAM domain (Sterile alpha motif) zf-DHHC PF01529.15 ETO00147.1 - 0.08 12.3 3.3 0.11 11.8 2.3 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase fn3 PF00041.16 ETO00148.1 - 0.0076 16.3 0.0 0.02 15.0 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain Daxx PF03344.10 ETO00148.1 - 0.01 14.3 9.7 0.014 13.8 6.7 1.1 1 0 0 1 1 1 0 Daxx Family Interfer-bind PF09294.5 ETO00148.1 - 0.042 13.8 0.7 0.16 11.9 0.0 2.3 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III CDC45 PF02724.9 ETO00148.1 - 0.66 7.9 8.1 1.1 7.2 5.6 1.4 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.20 ETO00149.1 - 4e-64 216.2 0.0 4.8e-64 215.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO00149.1 - 9.9e-26 90.3 0.0 1.3e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO00149.1 - 0.0028 16.6 0.0 0.033 13.1 0.0 2.1 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 ETO00149.1 - 0.01 15.5 0.0 0.035 13.8 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 ETO00149.1 - 0.06 12.6 0.0 0.093 12.0 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RUN PF02759.14 ETO00150.1 - 0.024 14.4 0.9 0.033 13.9 0.6 1.3 1 0 0 1 1 1 0 RUN domain Activator-TraM PF11657.3 ETO00150.1 - 0.077 12.4 0.9 1.7 8.1 0.1 2.1 1 1 0 2 2 2 0 Transcriptional activator TraM YxiJ PF14176.1 ETO00151.1 - 0.063 13.4 0.3 0.6 10.2 0.1 2.3 2 1 1 3 3 3 0 YxiJ-like protein Spt20 PF12090.3 ETO00152.1 - 0.023 14.0 3.8 0.024 14.0 2.6 1.1 1 0 0 1 1 1 0 Spt20 family Band_3_cyto PF07565.8 ETO00152.1 - 0.22 11.0 4.2 0.24 10.8 2.9 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4407 PF14362.1 ETO00152.1 - 0.35 9.7 3.7 0.31 9.9 2.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DOR PF14839.1 ETO00152.1 - 0.38 10.4 7.4 0.36 10.5 5.2 1.0 1 0 0 1 1 1 0 DOR family TSA PF03249.8 ETO00152.1 - 0.74 8.2 13.2 0.78 8.1 9.1 1.0 1 0 0 1 1 1 0 Type specific antigen UPF0542 PF15086.1 ETO00152.1 - 0.84 9.3 2.5 1.3 8.8 1.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 GTSE1_N PF15259.1 ETO00152.1 - 1.1 9.2 7.8 1.4 8.8 5.4 1.1 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 DUF4175 PF13779.1 ETO00152.1 - 1.3 6.6 15.1 1.3 6.6 10.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Med3 PF11593.3 ETO00152.1 - 1.4 8.0 14.7 1.6 7.8 10.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ATP-synt_E PF05680.7 ETO00152.1 - 2.1 8.3 7.7 2.8 7.9 5.3 1.1 1 0 0 1 1 1 0 ATP synthase E chain DUF106 PF01956.11 ETO00152.1 - 3.5 7.1 5.7 3.9 6.9 4.0 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 Gag_spuma PF03276.9 ETO00153.1 - 0.13 10.5 13.2 0.17 10.1 9.2 1.1 1 0 0 1 1 1 0 Spumavirus gag protein SAP PF02037.22 ETO00154.1 - 0.0033 16.9 0.0 0.0082 15.6 0.0 1.6 1 0 0 1 1 1 1 SAP domain FERM_C PF09380.5 ETO00154.1 - 0.0047 17.1 0.5 0.009 16.2 0.3 1.5 1 1 0 1 1 1 1 FERM C-terminal PH-like domain U-box PF04564.10 ETO00155.1 - 0.0052 16.7 1.2 0.11 12.4 0.3 2.7 2 0 0 2 2 2 1 U-box domain DUF1434 PF07254.7 ETO00155.1 - 0.016 15.0 5.0 2 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1434) YfiO PF13525.1 ETO00155.1 - 0.11 11.9 1.4 0.18 11.2 0.9 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein TACC PF05010.9 ETO00155.1 - 0.56 9.9 9.6 8.9 6.0 6.6 2.1 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) WD40 PF00400.27 ETO00156.1 - 8.6e-81 263.2 27.1 1.6e-13 49.9 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO00156.1 - 1.9e-06 26.4 1.6 0.012 13.9 0.0 3.7 1 1 3 4 4 4 4 Cytochrome D1 heme domain Ricin_B_lectin PF00652.17 ETO00156.1 - 0.017 15.1 2.2 0.24 11.4 0.5 2.7 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain PQQ_2 PF13360.1 ETO00156.1 - 0.039 13.4 1.3 0.75 9.1 0.1 2.6 3 1 0 4 4 4 0 PQQ-like domain PD40 PF07676.7 ETO00156.1 - 0.35 10.5 3.0 80 3.0 0.0 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO00156.1 - 0.48 10.7 8.5 4 7.7 0.1 4.6 3 1 3 6 6 6 0 Resistin TP53IP5 PF15331.1 ETO00157.1 - 4.3 7.1 9.3 5.3 6.8 6.4 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 MazG PF03819.12 ETO00158.1 - 0.078 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain TPR_12 PF13424.1 ETO00162.1 - 1.1e-10 41.2 1.0 1.8e-10 40.6 0.7 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO00162.1 - 1.2e-10 40.5 6.8 1.8e-06 27.2 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO00162.1 - 1.7e-10 40.3 3.8 3.2e-10 39.4 2.6 1.5 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 ETO00162.1 - 4.2e-10 38.7 3.3 7.2e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO00162.1 - 1.6e-07 30.6 7.9 9.9e-06 24.9 0.5 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO00162.1 - 1.4e-05 25.0 4.7 1.4e-05 25.0 3.2 2.0 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 ETO00162.1 - 3.9e-05 23.1 0.7 0.14 11.9 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO00162.1 - 9.5e-05 22.2 0.0 0.033 14.1 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO00162.1 - 0.00011 22.3 0.5 0.071 13.5 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO00162.1 - 0.00034 20.9 0.0 1 10.2 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO00162.1 - 0.00034 20.5 2.9 0.2 11.9 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_15 PF13429.1 ETO00162.1 - 0.00044 19.3 0.1 0.00057 19.0 0.1 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat SNAP PF14938.1 ETO00162.1 - 0.0013 17.9 3.0 0.0019 17.4 2.1 1.2 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_16 PF13432.1 ETO00162.1 - 0.004 17.7 0.0 0.0068 17.0 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat RPN7 PF10602.4 ETO00162.1 - 0.0044 16.4 3.0 0.095 12.0 0.1 2.2 1 1 1 2 2 2 1 26S proteasome subunit RPN7 DUF4080 PF13311.1 ETO00162.1 - 0.0099 15.9 4.1 0.016 15.2 2.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4080) MpPF26 PF07666.6 ETO00162.1 - 0.016 15.1 0.8 0.027 14.3 0.6 1.5 1 0 0 1 1 1 0 M penetrans paralogue family 26 TPR_3 PF07720.7 ETO00162.1 - 0.034 13.9 1.3 0.034 13.9 0.9 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETO00162.1 - 0.08 13.2 0.1 0.22 11.9 0.1 1.8 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF2989 PF11207.3 ETO00162.1 - 0.12 11.7 7.5 0.12 11.7 1.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2989) TPR_9 PF13371.1 ETO00162.1 - 0.13 12.1 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat YTH PF04146.10 ETO00162.1 - 0.19 11.3 0.4 0.19 11.3 0.3 1.8 2 1 0 2 2 2 0 YT521-B-like domain Tetraspannin PF00335.15 ETO00162.1 - 7.9 5.6 6.7 23 4.1 4.6 1.7 1 1 0 1 1 1 0 Tetraspanin family DehI PF10778.4 ETO00164.1 - 0.021 14.3 0.0 0.049 13.1 0.0 1.7 1 0 0 1 1 1 0 Halocarboxylic acid dehydrogenase DehI Glucosamine_iso PF01182.15 ETO00165.1 - 0.029 14.1 0.0 0.031 13.9 0.0 1.1 1 0 0 1 1 1 0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Seryl_tRNA_N PF02403.17 ETO00167.1 - 0.047 13.7 0.2 0.047 13.7 0.1 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Peptidase_C37 PF05416.7 ETO00168.1 - 0.32 9.2 8.7 0.39 8.9 6.0 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Hid1 PF12722.2 ETO00168.1 - 0.48 8.0 12.0 0.52 7.9 8.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4613 PF15390.1 ETO00168.1 - 1.8 6.6 10.8 2.2 6.3 7.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Zip PF02535.17 ETO00168.1 - 1.9 7.4 9.3 2.4 7.0 6.5 1.3 1 1 0 1 1 1 0 ZIP Zinc transporter NESP55 PF06390.7 ETO00168.1 - 3 7.1 9.0 1.9 7.8 4.9 1.4 1 1 1 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) Spore_III_AF PF09581.5 ETO00168.1 - 4.2 7.1 10.4 11 5.8 7.2 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) DUF2149 PF09919.4 ETO00168.1 - 4.5 7.4 8.4 0.55 10.3 0.6 2.5 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2149) EIIBC-GUT_N PF03612.9 ETO00168.1 - 4.5 6.8 8.1 3 7.4 0.6 2.1 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DUF1510 PF07423.6 ETO00168.1 - 8.8 5.6 24.3 0.064 12.6 0.6 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1510) DUF2358 PF10184.4 ETO00169.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2358) CENP-B_dimeris PF09026.5 ETO00170.1 - 2.6 8.3 5.0 3.6 7.8 3.5 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Secretin_N_2 PF07655.8 ETO00170.1 - 6.9 7.1 16.5 11 6.4 11.4 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain DUF3891 PF13030.1 ETO00171.1 - 0.064 12.7 0.0 0.071 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3891) Peptidase_M1 PF01433.15 ETO00172.1 - 0.00013 21.1 0.0 0.00015 21.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M1 WD40 PF00400.27 ETO00174.1 - 4.9e-22 76.9 7.5 5.6e-11 41.8 0.6 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO00174.1 - 9.4e-06 24.0 2.2 5.1e-05 21.5 0.3 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 U-box PF04564.10 ETO00176.1 - 9.4e-12 44.7 1.2 6.4e-11 42.0 0.0 2.7 2 1 0 2 2 2 1 U-box domain Kelch_6 PF13964.1 ETO00177.1 - 1.2e-06 28.4 0.9 1.8 8.9 0.0 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO00177.1 - 0.00039 19.8 1.1 2.8 7.5 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO00177.1 - 0.00085 19.4 0.3 0.29 11.3 0.0 4.2 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO00178.1 - 0.051 13.3 2.8 0.28 10.9 0.3 2.4 2 0 0 2 2 2 0 Galactose oxidase, central domain ZZ PF00569.12 ETO00179.1 - 0.014 14.8 6.2 0.014 14.8 4.3 2.5 1 1 1 2 2 2 0 Zinc finger, ZZ type FlxA PF14282.1 ETO00180.1 - 0.017 15.0 2.3 0.039 13.8 1.6 1.6 1 0 0 1 1 1 0 FlxA-like protein DUF3166 PF11365.3 ETO00180.1 - 0.2 12.1 2.6 0.63 10.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) GTP_EFTU_D4 PF14578.1 ETO00182.1 - 0.0058 16.2 0.0 0.03 13.9 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.20 ETO00182.1 - 0.034 14.2 0.0 0.064 13.3 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu domain 2 DUF3822 PF12864.2 ETO00182.1 - 0.034 13.3 0.0 0.042 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3822) zf-TRAF PF02176.13 ETO00185.1 - 3e-05 24.3 1.2 5.4e-05 23.4 0.8 1.5 1 0 0 1 1 1 1 TRAF-type zinc finger DUF484 PF04340.7 ETO00185.1 - 0.018 14.4 0.8 0.021 14.3 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF484 Syntaxin PF00804.20 ETO00185.1 - 0.041 14.0 10.0 0.057 13.5 7.0 1.2 1 0 0 1 1 1 0 Syntaxin DUF972 PF06156.8 ETO00185.1 - 0.11 12.8 4.3 0.14 12.5 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Fzo_mitofusin PF04799.8 ETO00185.1 - 0.12 11.7 6.2 0.051 12.9 2.0 1.7 1 1 1 2 2 2 0 fzo-like conserved region AcylCoA_dehyd_C PF12186.3 ETO00185.1 - 0.19 11.6 1.6 0.23 11.2 1.1 1.3 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase C terminal MRP-L46 PF11788.3 ETO00185.1 - 0.39 11.3 3.4 0.93 10.1 2.3 1.6 1 1 0 1 1 1 0 39S mitochondrial ribosomal protein L46 60KD_IMP PF02096.15 ETO00185.1 - 3.8 7.1 6.0 4.5 6.8 4.2 1.1 1 0 0 1 1 1 0 60Kd inner membrane protein Hydrolase_3 PF08282.7 ETO00186.1 - 0.018 14.5 0.0 0.021 14.3 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF809 PF05663.6 ETO00188.1 - 0.49 10.3 2.5 0.86 9.5 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF809) tRNA-Thr_ED PF08915.6 ETO00188.1 - 0.52 10.2 3.2 0.84 9.6 2.2 1.3 1 0 0 1 1 1 0 Archaea-specific editing domain of threonyl-tRNA synthetase DUF2413 PF10310.4 ETO00189.1 - 0.053 12.3 24.3 0.088 11.6 16.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) AAA_13 PF13166.1 ETO00189.1 - 0.2 10.1 26.9 0.23 9.8 18.7 1.0 1 0 0 1 1 1 0 AAA domain Adaptin_binding PF10199.4 ETO00189.1 - 0.25 11.6 25.2 0.43 10.8 17.4 1.5 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 BTV_NS2 PF04514.7 ETO00189.1 - 0.33 9.7 24.8 0.43 9.4 17.2 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Hid1 PF12722.2 ETO00189.1 - 1.7 6.1 21.1 2.1 5.9 14.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FGF-BP1 PF06473.7 ETO00189.1 - 4.3 6.8 18.6 6.2 6.3 12.9 1.3 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) U79_P34 PF03064.11 ETO00189.1 - 4.5 6.7 27.0 6.3 6.2 18.7 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Gag_spuma PF03276.9 ETO00189.1 - 9.3 4.4 8.8 12 4.1 6.1 1.1 1 0 0 1 1 1 0 Spumavirus gag protein PA26 PF04636.8 ETO00189.1 - 9.4 4.8 17.4 13 4.3 12.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PLRV_ORF5 PF01690.12 ETO00189.1 - 9.5 5.2 24.6 12 4.9 17.1 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein RhoGAP PF00620.22 ETO00190.1 - 0.0066 16.0 0.0 0.015 14.9 0.0 1.6 1 1 0 1 1 1 1 RhoGAP domain DUF2457 PF10446.4 ETO00190.1 - 0.49 9.0 7.9 0.72 8.5 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF912 PF06024.7 ETO00190.1 - 2.3 8.3 6.6 1.3e+02 2.6 4.6 2.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) UPF0180 PF03698.8 ETO00191.1 - 0.074 12.8 0.5 0.19 11.6 0.1 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0180) PRE_C2HC PF07530.6 ETO00191.1 - 0.65 9.9 3.9 0.16 11.8 0.3 1.8 2 1 0 2 2 2 0 Associated with zinc fingers WD40 PF00400.27 ETO00193.1 - 1.6e-26 91.1 0.6 7.4e-10 38.3 0.0 4.0 4 0 0 4 4 4 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO00193.1 - 0.021 13.5 0.0 1.3 7.6 0.0 2.1 1 1 1 2 2 2 0 Nup133 N terminal like ROS_MUCR PF05443.6 ETO00193.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein SPG48 PF14764.1 ETO00195.1 - 0.0029 16.1 0.5 0.004 15.6 0.3 1.2 1 0 0 1 1 1 1 AP-5 complex subunit, vesicle trafficking Imm39 PF15600.1 ETO00195.1 - 0.8 9.5 5.5 1.3 8.8 3.8 1.5 1 1 0 1 1 1 0 Immunity protein 39 Folate_carrier PF01770.13 ETO00196.1 - 0.39 9.1 3.3 0.48 8.8 2.3 1.1 1 0 0 1 1 1 0 Reduced folate carrier VTC PF09359.5 ETO00197.1 - 0.022 13.7 0.0 0.025 13.6 0.0 1.1 1 0 0 1 1 1 0 VTC domain PAS_6 PF08348.6 ETO00198.1 - 0.091 12.3 2.2 0.13 11.8 1.5 1.2 1 0 0 1 1 1 0 YheO-like PAS domain DUF972 PF06156.8 ETO00198.1 - 7.5 6.9 13.8 23 5.3 5.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) MitMem_reg PF13012.1 ETO00198.1 - 9.5 6.3 10.5 38 4.4 7.3 1.9 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function FH2 PF02181.18 ETO00199.1 - 0.00037 19.5 4.4 0.00042 19.3 3.1 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain Utp11 PF03998.8 ETO00199.1 - 0.039 13.7 9.1 0.042 13.6 6.3 1.0 1 0 0 1 1 1 0 Utp11 protein RED_N PF07808.8 ETO00199.1 - 0.04 13.1 7.0 0.045 12.9 4.9 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region FTA4 PF13093.1 ETO00199.1 - 0.084 12.2 6.2 0.1 11.9 4.3 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Mnd1 PF03962.10 ETO00199.1 - 0.13 11.9 9.1 0.17 11.5 6.3 1.3 1 0 0 1 1 1 0 Mnd1 family DUF3391 PF11871.3 ETO00199.1 - 0.17 12.0 3.6 0.24 11.6 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DUF365 PF04033.7 ETO00199.1 - 0.7 9.9 5.9 1 9.3 4.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF365) Microtub_bind PF13931.1 ETO00199.1 - 0.89 9.7 6.7 1.1 9.4 4.6 1.1 1 0 0 1 1 1 0 Kinesin-associated microtubule-binding RNase_HII PF01351.13 ETO00199.1 - 3.5 7.2 7.7 5.2 6.6 5.3 1.3 1 1 0 1 1 1 0 Ribonuclease HII AAA_23 PF13476.1 ETO00199.1 - 4.1 7.6 11.9 4.9 7.4 8.2 1.1 1 0 0 1 1 1 0 AAA domain Imm10 PF15562.1 ETO00201.1 - 0.71 9.6 3.4 1 9.1 0.1 2.3 2 1 0 2 2 2 0 Immunity protein 10 GTP_EFTU_D3 PF03143.12 ETO00202.1 - 0.016 15.3 0.1 0.034 14.3 0.0 1.6 1 1 0 1 1 1 0 Elongation factor Tu C-terminal domain Actin PF00022.14 ETO00202.1 - 0.041 12.3 0.0 0.041 12.3 0.0 1.2 1 0 0 1 1 1 0 Actin DUF3561 PF12084.3 ETO00205.1 - 0.027 14.2 0.2 0.28 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3561) DUF3618 PF12277.3 ETO00206.1 - 0.032 14.2 0.0 0.053 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) bZIP_2 PF07716.10 ETO00206.1 - 0.048 13.4 3.1 0.14 11.9 2.1 1.9 1 0 0 1 1 1 0 Basic region leucine zipper Tup_N PF08581.5 ETO00206.1 - 0.24 11.6 4.3 0.2 11.8 0.9 2.3 2 0 0 2 2 2 0 Tup N-terminal Lyase_catalyt PF09093.6 ETO00206.1 - 0.46 9.3 3.7 1 8.1 1.2 1.9 2 0 0 2 2 2 0 Lyase, catalytic TSC22 PF01166.13 ETO00206.1 - 0.78 9.7 4.7 0.63 10.0 0.7 2.7 2 1 1 3 3 3 0 TSC-22/dip/bun family Peptidase_S49_N PF08496.5 ETO00207.1 - 0.033 13.9 2.1 0.047 13.4 1.4 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CBM_21 PF03370.8 ETO00207.1 - 0.19 11.7 2.3 0.24 11.4 1.2 1.3 1 1 0 1 1 1 0 Putative phosphatase regulatory subunit DUF104 PF01954.11 ETO00207.1 - 1.8 8.6 9.6 4.9 7.2 3.5 2.6 3 0 0 3 3 3 0 Protein of unknown function DUF104 HYR PF02494.11 ETO00209.1 - 0.016 15.1 1.1 4 7.5 0.3 3.3 2 1 0 2 2 2 0 HYR domain Bap31 PF05529.7 ETO00209.1 - 0.071 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like ETRAMP PF09716.5 ETO00209.1 - 0.64 10.0 0.0 0.64 10.0 0.0 2.9 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) DUF987 PF06174.6 ETO00210.1 - 0.1 12.1 0.5 0.29 10.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF987) DUF724 PF05266.9 ETO00210.1 - 0.1 12.2 6.2 0.12 11.9 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Spc7 PF08317.6 ETO00210.1 - 0.18 10.4 5.3 0.18 10.4 3.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein YwqJ-deaminase PF14431.1 ETO00210.1 - 0.25 11.1 4.0 0.47 10.3 2.8 1.7 1 1 0 1 1 1 0 YwqJ-like deaminase Adaptin_binding PF10199.4 ETO00210.1 - 0.34 11.1 4.7 0.4 10.9 3.2 1.1 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 TMCO5 PF14992.1 ETO00210.1 - 1.7 7.7 6.6 1.8 7.6 4.6 1.0 1 0 0 1 1 1 0 TMCO5 family DUF342 PF03961.8 ETO00210.1 - 2.4 6.4 6.7 2.3 6.5 4.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Sec8_exocyst PF04048.9 ETO00210.1 - 2.8 7.5 6.3 3.9 7.1 4.4 1.3 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain IBR PF01485.16 ETO00212.1 - 0.043 13.6 1.1 0.1 12.4 0.8 1.6 1 0 0 1 1 1 0 IBR domain Pinin_SDK_memA PF04696.8 ETO00212.1 - 0.24 11.0 11.5 0.37 10.3 8.0 1.3 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region FERM_M PF00373.13 ETO00212.1 - 0.87 9.7 5.0 0.18 11.9 0.3 2.2 2 1 0 2 2 2 0 FERM central domain Yip1 PF04893.12 ETO00214.1 - 0.37 10.2 6.2 3.2 7.2 0.1 2.2 2 0 0 2 2 2 0 Yip1 domain Bacteriocin_IIc PF10439.4 ETO00214.1 - 0.42 10.7 11.0 35 4.6 5.8 3.8 3 1 0 3 3 3 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.1 ETO00214.1 - 0.94 9.1 9.5 2.8 7.6 4.8 2.5 2 1 0 2 2 2 0 Glycine zipper BTB PF00651.26 ETO00217.1 - 7.5e-08 32.3 0.0 2.2e-07 30.8 0.0 1.8 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.10 ETO00217.1 - 0.00039 20.2 2.1 0.19 11.5 0.6 3.3 2 1 1 3 3 3 2 BTB And C-terminal Kelch U-box PF04564.10 ETO00218.1 - 2.2e-10 40.3 0.0 6.1e-10 38.9 0.0 1.8 1 1 0 1 1 1 1 U-box domain Rep_fac-A_3 PF08661.6 ETO00218.1 - 0.073 12.9 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Replication factor A protein 3 ERAP1_C PF11838.3 ETO00218.1 - 0.1 11.7 0.2 0.16 11.1 0.2 1.3 1 0 0 1 1 1 0 ERAP1-like C-terminal domain CBS PF00571.23 ETO00219.1 - 4e-06 26.5 0.0 1.2e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 CBS domain DUF2870 PF11069.3 ETO00219.1 - 0.087 12.8 1.1 0.71 9.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) AAA_13 PF13166.1 ETO00221.1 - 0.0059 15.1 4.5 0.0062 15.0 3.1 1.0 1 0 0 1 1 1 1 AAA domain Tho2 PF11262.3 ETO00221.1 - 0.022 13.8 5.4 0.021 13.8 3.7 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Spore_III_AF PF09581.5 ETO00221.1 - 0.059 13.2 3.7 0.068 13.0 2.6 1.0 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Atg14 PF10186.4 ETO00221.1 - 0.065 12.1 6.9 0.073 11.9 4.8 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Bap31 PF05529.7 ETO00221.1 - 0.86 9.0 4.8 0.88 8.9 3.3 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF4407 PF14362.1 ETO00221.1 - 0.96 8.3 2.7 1.1 8.1 1.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YqfQ PF14181.1 ETO00221.1 - 0.99 9.4 8.0 1.1 9.2 5.6 1.1 1 0 0 1 1 1 0 YqfQ-like protein ATP-synt_E PF05680.7 ETO00221.1 - 2.2 8.2 7.3 2.8 7.9 5.1 1.2 1 0 0 1 1 1 0 ATP synthase E chain Gag_spuma PF03276.9 ETO00221.1 - 3.7 5.7 5.3 4.3 5.5 3.7 1.0 1 0 0 1 1 1 0 Spumavirus gag protein DUF4337 PF14235.1 ETO00221.1 - 9.8 5.9 7.5 12 5.7 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Pkinase PF00069.20 ETO00222.1 - 1.8e-44 151.8 0.0 2.1e-44 151.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO00222.1 - 1e-27 96.8 0.0 1.3e-27 96.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETO00222.1 - 1.3e-06 28.3 0.0 0.0081 15.9 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 ETO00222.1 - 1.4e-06 27.5 0.3 6.4e-06 25.3 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 ETO00222.1 - 0.0022 17.5 0.2 0.0067 16.0 0.1 1.7 1 1 1 2 2 2 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 ETO00222.1 - 0.042 13.1 0.0 0.068 12.4 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Peptidase_S49_N PF08496.5 ETO00223.1 - 0.38 10.5 2.3 0.45 10.3 1.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TipAS PF07739.8 ETO00223.1 - 1.9 8.8 6.2 3.9 7.8 4.3 1.5 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain Peptidase_C14 PF00656.17 ETO00224.1 - 2.8e-05 23.9 0.4 2.9e-05 23.8 0.3 1.2 1 1 0 1 1 1 1 Caspase domain DUF2439 PF10382.4 ETO00226.1 - 0.072 13.3 0.4 0.14 12.4 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2439) PUB PF09409.5 ETO00227.1 - 0.0012 18.5 3.3 0.0027 17.4 0.3 2.9 2 2 1 3 3 3 1 PUB domain DnaG_DnaB_bind PF08278.6 ETO00227.1 - 0.015 15.4 2.2 0.025 14.8 1.5 1.3 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding Hint PF01079.15 ETO00227.1 - 0.04 13.1 0.5 0.057 12.6 0.4 1.1 1 0 0 1 1 1 0 Hint module CUE PF02845.11 ETO00227.1 - 0.23 10.9 0.1 0.23 10.9 0.1 2.1 2 0 0 2 2 2 0 CUE domain TPR_19 PF14559.1 ETO00229.1 - 3.7e-07 30.3 0.1 9.5e-07 29.0 0.0 1.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO00229.1 - 9.2e-07 28.3 0.1 1.4 9.0 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO00229.1 - 1.1e-06 28.7 0.1 0.016 15.7 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO00229.1 - 6.8e-06 26.1 0.2 0.82 10.2 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 ETO00229.1 - 6.2e-05 22.1 0.2 6.9e-05 22.0 0.1 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO00229.1 - 7e-05 22.4 0.1 0.00083 18.9 0.0 2.3 2 1 0 2 2 2 1 TPR repeat Apc3 PF12895.2 ETO00229.1 - 0.00011 22.3 0.1 0.00012 22.1 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 ETO00229.1 - 0.00019 22.0 0.1 0.036 14.7 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat Coatomer_E PF04733.9 ETO00229.1 - 0.00063 19.0 0.0 0.00071 18.8 0.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_20 PF14561.1 ETO00229.1 - 0.0017 18.4 0.0 0.0072 16.4 0.0 1.8 1 1 1 2 2 2 1 Tetratricopeptide repeat NARP1 PF12569.3 ETO00229.1 - 0.0046 15.7 0.0 0.0059 15.4 0.0 1.0 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_1 PF00515.23 ETO00229.1 - 0.0053 16.3 0.1 13 5.6 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.4 ETO00229.1 - 0.0064 16.4 0.0 0.008 16.1 0.0 1.3 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETO00229.1 - 0.0078 16.0 0.2 0.051 13.4 0.0 2.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO00229.1 - 0.032 14.1 0.3 0.23 11.4 0.1 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat Cas_Cas02710 PF09670.5 ETO00229.1 - 0.052 12.1 0.0 0.059 11.9 0.0 1.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) Daxx PF03344.10 ETO00231.1 - 0.74 8.2 24.7 0.93 7.9 17.1 1.0 1 0 0 1 1 1 0 Daxx Family WD40 PF00400.27 ETO00232.1 - 1.7e-13 49.8 3.0 9.5e-11 41.1 0.5 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO00232.1 - 0.00015 20.0 0.1 0.00015 20.0 0.1 1.0 1 0 0 1 1 1 1 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO00232.1 - 0.0047 16.2 1.0 0.0056 16.0 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4221) DUF2400 PF09674.5 ETO00233.1 - 0.13 11.9 9.3 0.85 9.2 5.4 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2400) HBS1_N PF08938.5 ETO00233.1 - 1.3 9.1 7.7 0.76 9.9 2.6 2.4 2 0 0 2 2 2 0 HBS1 N-terminus BRICHOS PF04089.9 ETO00233.1 - 4.5 7.2 9.5 0.86 9.4 0.7 2.9 2 1 1 3 3 3 0 BRICHOS domain DUF4536 PF15055.1 ETO00234.1 - 0.13 12.3 0.0 15 5.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) BUD22 PF09073.5 ETO00235.1 - 0.67 8.9 7.1 0.92 8.5 4.9 1.2 1 0 0 1 1 1 0 BUD22 ICAT PF06384.6 ETO00236.1 - 0.0042 16.8 0.5 0.037 13.8 0.0 2.4 3 0 0 3 3 3 1 Beta-catenin-interacting protein ICAT Pneumovirus_M2 PF06436.6 ETO00237.1 - 0.059 12.6 0.1 0.078 12.2 0.1 1.2 1 0 0 1 1 1 0 Pneumovirus matrix protein 2 (M2) HEAT_2 PF13646.1 ETO00239.1 - 4.8e-09 36.3 0.0 0.17 12.1 0.0 4.1 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 ETO00239.1 - 0.00018 21.9 0.0 1.2 9.7 0.0 4.0 4 0 0 4 4 4 1 HEAT-like repeat HEAT PF02985.17 ETO00239.1 - 0.002 18.0 2.3 26 5.2 0.0 5.5 6 0 0 6 6 6 0 HEAT repeat Cnd1 PF12717.2 ETO00239.1 - 0.024 14.4 16.9 1.1 9.0 1.8 3.6 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 MOR2-PAG1_C PF14225.1 ETO00239.1 - 0.036 13.8 8.5 0.12 12.1 0.2 3.5 1 1 2 4 4 4 0 Cell morphogenesis C-terminal CLASP_N PF12348.3 ETO00239.1 - 0.037 13.3 8.8 0.051 12.9 1.4 3.1 2 2 0 2 2 2 0 CLASP N terminal DUF2614 PF11023.3 ETO00239.1 - 0.042 13.6 1.1 25 4.6 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2614) Utp21 PF04192.7 ETO00239.1 - 0.067 12.2 3.4 0.58 9.2 0.2 2.2 2 0 0 2 2 2 0 Utp21 specific WD40 associated putative domain Pribosyltran_N PF13793.1 ETO00239.1 - 0.37 10.5 1.8 0.54 10.0 0.5 1.9 2 1 0 2 2 2 0 N-terminal domain of ribose phosphate pyrophosphokinase AAA_18 PF13238.1 ETO00239.1 - 0.52 10.6 3.1 8.6 6.6 0.6 2.6 2 1 0 2 2 2 0 AAA domain ENTH PF01417.15 ETO00239.1 - 0.58 10.0 4.8 2 8.2 1.3 3.1 1 1 2 3 3 3 0 ENTH domain DUF4485 PF14846.1 ETO00239.1 - 1.1 8.9 11.4 0.98 9.1 0.5 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4485) DUF3944 PF13099.1 ETO00239.1 - 2.2 7.8 9.7 1.1 8.8 0.2 4.1 5 0 0 5 5 5 0 Domain of unknown function (DUF3944) IPK PF03770.11 ETO00239.1 - 2.3 7.8 7.0 1.2 8.7 1.2 2.6 1 1 1 2 2 2 0 Inositol polyphosphate kinase H2TH PF06831.9 ETO00241.1 - 0.034 13.8 0.1 0.076 12.7 0.1 1.6 1 1 0 1 1 1 0 Formamidopyrimidine-DNA glycosylase H2TH domain Pkinase PF00069.20 ETO00243.1 - 3.5e-34 118.1 1.8 4.4e-33 114.5 0.2 2.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO00243.1 - 3.9e-21 75.2 0.2 2.6e-14 52.9 0.1 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase FliT PF05400.8 ETO00243.1 - 0.055 13.8 2.3 5.2 7.5 0.0 2.6 3 0 0 3 3 3 0 Flagellar protein FliT DIOX_N PF14226.1 ETO00245.1 - 2.9e-14 53.6 0.0 5.7e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETO00245.1 - 6.7e-11 42.3 0.1 3.8e-10 39.9 0.0 2.2 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily Homeobox PF00046.24 ETO00245.1 - 0.058 13.0 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Homeobox domain DUF904 PF06005.7 ETO00246.1 - 0.00059 20.0 2.5 0.00059 20.0 1.7 10.4 8 3 2 10 10 10 3 Protein of unknown function (DUF904) DUF2782 PF11191.3 ETO00246.1 - 1.6 8.7 6.9 0.23 11.4 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2782) TIP41 PF04176.8 ETO00247.1 - 3.7 6.7 6.6 2.8 7.1 0.2 2.2 2 0 0 2 2 2 0 TIP41-like family PH PF00169.24 ETO00248.1 - 2.3e-10 40.6 2.0 3.1e-10 40.1 0.2 2.1 2 0 0 2 2 2 1 PH domain PH_3 PF14593.1 ETO00248.1 - 1.4e-08 34.5 0.9 2.8e-08 33.5 0.6 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 ETO00248.1 - 4.8e-08 32.9 1.7 6.2e-08 32.6 0.5 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.1 ETO00248.1 - 8.8e-08 32.3 9.7 1.3e-06 28.5 4.0 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain Mcp5_PH PF12814.2 ETO00248.1 - 0.11 12.4 3.0 0.18 11.7 0.6 2.6 2 1 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology NAD_kinase PF01513.16 ETO00249.1 - 2.2e-51 174.3 0.0 5.9e-51 172.9 0.0 1.8 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 ETO00249.1 - 0.0034 16.8 0.0 0.0069 15.8 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF3595 PF12166.3 ETO00250.1 - 0.019 13.7 1.9 0.023 13.5 1.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) Senescence_reg PF04520.8 ETO00250.1 - 0.057 13.9 2.3 0.087 13.3 1.6 1.4 1 0 0 1 1 1 0 Senescence regulator Laps PF10169.4 ETO00250.1 - 0.079 13.1 2.3 0.093 12.9 1.1 1.5 1 1 0 1 1 1 0 Learning-associated protein DUF2431 PF10354.4 ETO00250.1 - 0.18 11.7 3.4 0.34 10.8 2.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF2431) BLOC1_2 PF10046.4 ETO00250.1 - 3.4 7.8 9.9 15 5.8 4.5 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4131 PF13567.1 ETO00251.1 - 0.078 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Ppx-GppA PF02541.11 ETO00251.1 - 0.085 12.0 4.5 2.6 7.1 0.0 2.8 3 0 0 3 3 3 0 Ppx/GppA phosphatase family WD40 PF00400.27 ETO00253.1 - 1.2e-11 44.0 0.3 1.2e-11 44.0 0.2 3.0 3 1 0 3 3 3 1 WD domain, G-beta repeat UpxZ PF06603.6 ETO00253.1 - 0.045 13.7 0.0 0.06 13.3 0.0 1.2 1 0 0 1 1 1 0 UpxZ family of transcription anti-terminator antagonists SWIM PF04434.12 ETO00253.1 - 0.047 13.1 1.9 0.057 12.9 0.3 1.9 2 0 0 2 2 2 0 SWIM zinc finger DUF2677 PF10838.3 ETO00253.1 - 0.048 13.3 2.7 0.23 11.1 1.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2677) Cnd1_N PF12922.2 ETO00254.1 - 0.097 12.2 0.3 0.097 12.2 0.2 1.6 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term YoqO PF14037.1 ETO00254.1 - 0.1 12.6 5.4 0.24 11.5 3.7 1.7 1 1 0 1 1 1 0 YoqO-like protein DUF3896 PF13035.1 ETO00256.1 - 0.15 12.1 0.4 0.15 12.1 0.3 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3896) TMF_TATA_bd PF12325.3 ETO00256.1 - 0.3 10.8 11.2 0.083 12.6 1.3 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF465 PF04325.8 ETO00256.1 - 1 9.1 5.2 2.4 7.9 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF465) APG6 PF04111.7 ETO00256.1 - 1.1 8.2 13.3 0.53 9.2 0.7 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 HALZ PF02183.13 ETO00256.1 - 1.1 8.9 7.5 0.87 9.3 1.9 2.6 2 1 0 2 2 2 0 Homeobox associated leucine zipper DUF4337 PF14235.1 ETO00256.1 - 1.3 8.8 11.0 2.7 7.8 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Exonuc_VII_L PF02601.10 ETO00256.1 - 2 7.5 5.8 2.4 7.2 4.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit NAM-associated PF14303.1 ETO00256.1 - 2.4 8.4 15.1 0.78 10.0 1.9 2.1 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain ERM PF00769.14 ETO00256.1 - 3.8 6.9 16.5 0.79 9.2 2.4 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Phage_GP20 PF06810.6 ETO00256.1 - 6.5 6.1 11.2 0.5 9.7 0.2 2.3 2 1 0 2 2 2 0 Phage minor structural protein GP20 Kelch_6 PF13964.1 ETO00257.1 - 5.3e-05 23.2 2.4 0.38 11.0 0.2 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO00257.1 - 0.00054 19.4 2.5 0.0018 17.7 0.1 2.8 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO00257.1 - 0.0013 18.4 1.1 1.1 9.1 0.1 4.3 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO00257.1 - 0.0014 18.3 0.3 0.13 12.0 0.0 3.0 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO00257.1 - 0.0029 17.5 0.0 1.6 8.8 0.1 3.7 4 0 0 4 4 4 1 Kelch motif RasGEF_N PF00618.15 ETO00258.1 - 4e-06 26.8 2.7 3.8e-05 23.7 0.3 2.0 1 1 1 2 2 2 2 RasGEF N-terminal motif WD40 PF00400.27 ETO00259.1 - 8.9e-09 34.9 6.3 9.9e-05 22.0 1.6 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO00259.1 - 0.0026 15.9 0.1 0.0028 15.8 0.1 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 WD40 PF00400.27 ETO00261.1 - 2.7e-21 74.5 9.7 7.2e-11 41.5 1.7 3.3 4 0 0 4 4 4 2 WD domain, G-beta repeat Med9 PF07544.8 ETO00261.1 - 0.0098 15.6 8.9 0.0098 15.6 6.2 2.0 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 BBS2_Mid PF14783.1 ETO00261.1 - 0.023 14.4 2.9 4.7 7.0 0.1 2.9 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region TMCO5 PF14992.1 ETO00261.1 - 0.081 12.0 23.2 0.087 11.9 15.3 1.5 1 1 1 2 2 2 0 TMCO5 family Noelin-1 PF12308.3 ETO00261.1 - 0.89 9.3 8.6 0.49 10.2 3.1 2.5 2 1 1 3 3 3 0 Neurogenesis glycoprotein LMBR1 PF04791.11 ETO00261.1 - 0.94 7.9 4.4 0.99 7.9 3.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Atg14 PF10186.4 ETO00261.1 - 1.2 8.0 23.2 2.2 7.1 16.1 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Cytadhesin_P30 PF07271.6 ETO00261.1 - 8.2 5.6 10.6 0.32 10.2 3.3 1.5 1 1 1 2 2 2 0 Cytadhesin P30/P32 Pkinase PF00069.20 ETO00262.1 - 9.5e-27 93.7 5.0 2.5e-25 89.1 3.5 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO00262.1 - 1.3e-12 47.3 2.4 7e-11 41.6 0.1 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase EcKinase PF02958.15 ETO00262.1 - 0.029 13.5 0.2 0.035 13.2 0.2 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase DUF1569 PF07606.6 ETO00262.1 - 0.044 13.6 1.3 0.066 13.1 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1569) DUF1128 PF06569.6 ETO00262.1 - 0.11 12.1 0.2 5.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) Pkinase PF00069.20 ETO00264.1 - 1.5e-09 37.4 0.4 3.1e-08 33.0 0.3 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO00264.1 - 0.041 12.9 0.4 1.7 7.6 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase PB1 PF00564.19 ETO00265.1 - 0.0079 15.8 0.7 0.016 14.8 0.5 1.6 1 0 0 1 1 1 1 PB1 domain Annexin PF00191.15 ETO00267.1 - 0.0029 17.4 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 Annexin HEAT_2 PF13646.1 ETO00272.1 - 0.00031 20.9 0.0 0.0072 16.5 0.0 2.0 1 1 1 2 2 2 2 HEAT repeats DUF3137 PF11335.3 ETO00272.1 - 0.00074 19.2 0.0 0.001 18.7 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3137) HEAT PF02985.17 ETO00272.1 - 0.0013 18.5 0.1 0.56 10.4 0.0 3.4 4 0 0 4 4 4 1 HEAT repeat HTH_16 PF12645.2 ETO00273.1 - 0.13 12.2 1.7 0.15 12.0 0.2 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain PHA-1 PF06542.6 ETO00274.1 - 0.0024 16.6 3.7 0.0027 16.5 2.3 1.3 1 1 0 1 1 1 1 Regulator protein PHA-1 SusD-like_3 PF14322.1 ETO00275.1 - 1 9.3 7.8 0.14 12.2 1.6 2.0 1 1 1 2 2 2 0 Starch-binding associating with outer membrane Nop14 PF04147.7 ETO00276.1 - 0.04 11.8 4.9 0.04 11.8 3.4 1.1 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.7 ETO00276.1 - 5 6.1 13.6 4.8 6.2 7.7 2.0 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT PT PF04886.7 ETO00277.1 - 1.5e-10 40.2 36.6 4.6 6.6 25.4 3.4 1 1 0 1 1 1 1 PT repeat DUF4106 PF13388.1 ETO00277.1 - 0.11 11.4 12.7 0.15 11.0 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Peripla_BP_4 PF13407.1 ETO00279.1 - 0.076 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain GRP PF07172.6 ETO00281.1 - 0.53 10.8 2.9 0.36 11.3 0.4 1.8 1 1 1 2 2 2 0 Glycine rich protein family VID27 PF08553.5 ETO00281.1 - 2.7 6.0 8.8 2.8 6.0 6.1 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein CDC45 PF02724.9 ETO00281.1 - 7.4 4.4 7.9 7.3 4.4 5.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.8 ETO00281.1 - 7.5 4.1 17.8 12 3.5 12.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi Tubulin PF00091.20 ETO00283.1 - 2.5e-51 174.5 0.1 7e-51 173.0 0.1 1.8 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO00283.1 - 1.5e-49 167.2 0.1 2.6e-49 166.4 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 ETO00283.1 - 2.1e-05 24.5 0.0 3.7e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Lactonase PF10282.4 ETO00284.1 - 3e-15 56.1 0.0 4.2e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DUF2139 PF09910.4 ETO00284.1 - 0.097 11.6 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2139) PfkB PF00294.19 ETO00285.1 - 0.14 11.2 0.3 0.14 11.2 0.2 1.0 1 0 0 1 1 1 0 pfkB family carbohydrate kinase ATP-synt_E PF05680.7 ETO00285.1 - 0.16 11.9 3.5 0.18 11.7 2.4 1.2 1 0 0 1 1 1 0 ATP synthase E chain Poxvirus_B22R PF04395.7 ETO00285.1 - 0.21 11.0 5.1 0.23 10.9 3.5 1.0 1 0 0 1 1 1 0 Poxvirus B22R protein Spore_II_R PF09551.5 ETO00285.1 - 0.53 10.3 4.1 0.61 10.1 2.7 1.2 1 1 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) DUF4337 PF14235.1 ETO00285.1 - 0.55 10.0 3.0 0.55 10.0 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Ribosomal_L30_N PF08079.7 ETO00285.1 - 1.1 9.3 15.3 1.4 9.0 10.6 1.3 1 1 0 1 1 1 0 Ribosomal L30 N-terminal domain SR-25 PF10500.4 ETO00285.1 - 2 7.8 10.9 2.1 7.7 7.6 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Seryl_tRNA_N PF02403.17 ETO00285.1 - 2.2 8.3 11.5 2.3 8.2 7.8 1.2 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain zf-DHHC PF01529.15 ETO00285.1 - 2.3 7.5 4.1 2.7 7.3 2.8 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF3671 PF12420.3 ETO00285.1 - 3.5 7.6 9.5 4 7.4 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function Peptidase_S49_N PF08496.5 ETO00285.1 - 5.8 6.6 7.8 5.7 6.7 5.4 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RNA_pol_Rpb1_7 PF04990.7 ETO00287.1 - 0.063 12.9 0.5 0.087 12.5 0.3 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 7 WD40 PF00400.27 ETO00288.1 - 2.9e-23 80.8 7.5 5e-11 42.0 0.7 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO00288.1 - 0.025 12.7 1.0 4.1 5.4 0.1 2.7 1 1 2 3 3 3 0 Nucleoporin Nup120/160 WD40 PF00400.27 ETO00289.1 - 1e-58 193.2 20.6 2.4e-10 39.8 0.1 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO00289.1 - 2.9e-10 38.9 6.8 0.0037 15.4 0.2 5.0 3 1 2 5 5 5 5 Nucleoporin Nup120/160 DUF1900 PF08954.6 ETO00289.1 - 0.1 12.1 1.3 4.2 6.8 0.0 3.7 4 1 1 5 5 5 0 Domain of unknown function (DUF1900) GBP_C PF02841.9 ETO00291.1 - 0.021 14.0 6.9 0.024 13.8 4.8 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain XAP5 PF04921.9 ETO00291.1 - 2 7.9 15.3 2.8 7.4 10.6 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator Daxx PF03344.10 ETO00291.1 - 4.2 5.7 25.9 4.9 5.5 18.0 1.0 1 0 0 1 1 1 0 Daxx Family WBS_methylT PF12589.3 ETO00291.1 - 5.5 7.5 9.6 77 3.8 6.6 2.2 1 1 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome EBV-NA3 PF05009.7 ETO00291.1 - 5.9 6.0 8.1 8.9 5.4 5.6 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) CENP-T PF15511.1 ETO00291.1 - 6 6.0 17.1 6.9 5.8 11.9 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF2457 PF10446.4 ETO00291.1 - 6.6 5.3 27.4 7.7 5.1 19.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) VID27 PF08553.5 ETO00291.1 - 8.5 4.4 17.9 8.7 4.4 12.4 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein zf-Tim10_DDP PF02953.10 ETO00293.1 - 0.0037 16.5 0.6 0.0093 15.2 0.4 1.6 1 0 0 1 1 1 1 Tim10/DDP family zinc finger RED_N PF07808.8 ETO00294.1 - 0.074 12.2 2.1 0.079 12.1 1.4 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region Ank_2 PF12796.2 ETO00295.1 - 0.00028 21.1 0.3 0.00095 19.4 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO00295.1 - 0.00054 20.3 0.3 0.002 18.5 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO00295.1 - 0.025 14.7 0.1 1.3 9.4 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat Cnd1 PF12717.2 ETO00295.1 - 0.18 11.6 5.3 9.4 6.0 3.6 2.4 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Uso1_p115_head PF04869.9 ETO00296.1 - 0.011 14.4 0.1 0.023 13.4 0.0 1.4 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, head region Myosin_tail_1 PF01576.14 ETO00297.1 - 3.3e-06 25.1 26.7 4.3e-06 24.7 18.5 1.1 1 0 0 1 1 1 1 Myosin tail Reo_sigmaC PF04582.7 ETO00297.1 - 0.00064 18.9 3.4 0.014 14.5 0.5 2.1 1 1 1 2 2 2 2 Reovirus sigma C capsid protein Pro-rich_19 PF15455.1 ETO00297.1 - 0.0019 17.2 0.4 0.0035 16.4 0.3 1.3 1 0 0 1 1 1 1 Proline-rich 19 DUF3584 PF12128.3 ETO00297.1 - 0.003 15.0 29.7 0.004 14.5 20.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) WEMBL PF05701.6 ETO00297.1 - 0.1 11.0 23.9 0.15 10.4 16.6 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Mnd1 PF03962.10 ETO00297.1 - 0.16 11.6 32.2 0.41 10.2 11.6 2.3 1 1 1 2 2 2 0 Mnd1 family Lebercilin PF15619.1 ETO00297.1 - 0.34 10.2 35.0 0.19 11.1 20.3 2.4 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease V_ATPase_I PF01496.14 ETO00297.1 - 0.43 8.3 16.9 0.74 7.5 11.7 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PilJ PF13675.1 ETO00297.1 - 0.77 10.1 7.9 0.33 11.2 1.8 2.3 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term CENP-F_leu_zip PF10473.4 ETO00297.1 - 0.79 9.5 35.5 0.74 9.6 4.2 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIVA PF05103.8 ETO00297.1 - 2.6 8.1 35.3 0.59 10.1 14.3 2.3 1 1 1 2 2 2 0 DivIVA protein Spc7 PF08317.6 ETO00297.1 - 3.4 6.2 40.9 1.2 7.7 15.7 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF641 PF04859.7 ETO00297.1 - 3.8 7.2 26.5 0.65 9.7 4.4 3.3 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) TPR_MLP1_2 PF07926.7 ETO00297.1 - 5.7 6.6 38.7 11 5.7 14.3 3.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Phage_GP20 PF06810.6 ETO00297.1 - 6.2 6.2 48.2 0.21 11.0 14.1 4.0 1 1 4 5 5 5 0 Phage minor structural protein GP20 DUF1664 PF07889.7 ETO00297.1 - 7.6 6.3 25.9 0.98 9.2 0.7 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Reprolysin_5 PF13688.1 ETO00299.1 - 0.06 13.2 1.7 0.074 12.9 1.2 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12 Dehalogenase PF13486.1 ETO00300.1 - 0.0039 16.6 0.5 0.0051 16.3 0.3 1.2 1 0 0 1 1 1 1 Reductive dehalogenase subunit F-actin_cap_A PF01267.12 ETO00300.1 - 0.018 14.1 1.3 0.022 13.8 0.9 1.2 1 0 0 1 1 1 0 F-actin capping protein alpha subunit MFS_Mycoplasma PF07672.8 ETO00300.1 - 0.038 13.1 0.6 0.061 12.4 0.4 1.3 1 0 0 1 1 1 0 Mycoplasma MFS transporter UMP1 PF05348.6 ETO00300.1 - 0.1 12.5 1.2 0.19 11.6 0.8 1.4 1 0 0 1 1 1 0 Proteasome maturation factor UMP1 TPR_12 PF13424.1 ETO00302.1 - 2.6e-23 81.7 6.0 1.3e-14 53.8 0.8 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO00302.1 - 1.1e-12 47.4 7.9 7.2e-09 35.1 1.1 2.0 1 1 1 2 2 2 2 TPR repeat TPR_7 PF13176.1 ETO00302.1 - 1.4e-12 46.3 1.0 8.2e-06 25.2 0.2 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO00302.1 - 7.9e-12 44.1 4.9 2.9e-07 29.8 0.8 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO00302.1 - 1e-11 43.8 7.4 2e-06 27.1 1.5 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO00302.1 - 2.3e-09 36.3 11.8 4.2e-07 29.2 2.1 2.7 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO00302.1 - 5.1e-07 29.7 0.8 0.0001 22.5 0.3 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO00302.1 - 8.1e-07 28.7 0.4 0.091 13.0 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO00302.1 - 1.3e-06 28.4 2.3 0.00023 21.2 0.9 3.0 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 ETO00302.1 - 2.7e-06 27.9 0.0 0.002 18.7 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_3 PF07720.7 ETO00302.1 - 8.9e-06 25.3 10.0 0.13 12.1 0.1 3.6 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO00302.1 - 3.1e-05 23.7 0.0 0.019 14.8 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO00302.1 - 6.2e-05 23.2 0.1 0.062 13.9 0.0 2.6 3 0 0 3 3 2 1 Tetratricopeptide repeat SNAP PF14938.1 ETO00302.1 - 0.0059 15.7 0.1 0.0074 15.4 0.1 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP DUF1722 PF08349.6 ETO00302.1 - 0.025 14.4 0.2 0.038 13.8 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1722) MIT PF04212.13 ETO00302.1 - 0.044 13.6 1.6 0.41 10.5 0.5 2.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.1 ETO00302.1 - 0.074 13.4 0.3 0.92 9.8 0.1 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat Ubiq-assoc PF09145.5 ETO00302.1 - 0.14 12.0 4.4 1.6 8.6 0.2 2.8 2 1 1 3 3 3 0 Ubiquitin-associated Sel1 PF08238.7 ETO00302.1 - 0.14 12.7 2.5 1.5 9.5 1.1 2.6 3 0 0 3 3 3 0 Sel1 repeat Cellulase PF00150.13 ETO00303.1 - 0.017 14.3 0.1 0.021 14.0 0.1 1.1 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) PDR_CDR PF06422.7 ETO00304.1 - 0.00095 18.7 0.1 0.0014 18.2 0.1 1.2 1 0 0 1 1 1 1 CDR ABC transporter Zn-ribbon_8 PF09723.5 ETO00304.1 - 0.052 13.4 0.0 0.092 12.7 0.0 1.3 1 0 0 1 1 1 0 Zinc ribbon domain ResB PF05140.9 ETO00306.1 - 0.11 10.9 0.1 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 ResB-like family COG2 PF06148.6 ETO00306.1 - 0.47 10.3 5.9 0.24 11.2 2.2 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1018 PF06252.7 ETO00308.1 - 0.034 14.6 0.0 0.056 13.9 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) DUF4416 PF14385.1 ETO00308.1 - 0.084 12.5 1.4 0.12 12.0 0.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4416) DUF2536 PF10750.4 ETO00308.1 - 0.24 11.0 5.1 0.081 12.5 0.9 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2536) Sedlin_N PF04628.8 ETO00308.1 - 0.47 10.3 3.1 0.65 9.8 2.1 1.4 1 1 0 1 1 1 0 Sedlin, N-terminal conserved region Kelch_6 PF13964.1 ETO00309.1 - 1.4e-08 34.5 0.5 5e-06 26.4 0.1 2.5 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 ETO00309.1 - 5e-08 32.3 1.3 2.3e-07 30.2 0.8 2.0 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO00309.1 - 0.00023 21.2 0.0 0.00061 19.8 0.0 1.7 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO00309.1 - 0.00075 19.3 0.2 0.0073 16.2 0.3 2.2 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.1 ETO00309.1 - 0.011 15.4 0.0 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 Galactose oxidase, central domain RAG2 PF03089.9 ETO00309.1 - 0.03 13.0 0.1 0.047 12.4 0.0 1.3 1 1 0 1 1 1 0 Recombination activating protein 2 Kelch_2 PF07646.10 ETO00309.1 - 0.046 13.5 0.5 0.1 12.4 0.3 1.6 1 0 0 1 1 1 0 Kelch motif PA14_2 PF10528.4 ETO00309.1 - 0.23 11.4 1.5 0.39 10.7 0.3 1.8 1 1 1 2 2 2 0 GLEYA domain NACHT PF05729.7 ETO00310.1 - 0.0027 17.3 0.0 0.0027 17.3 0.0 1.1 1 0 0 1 1 1 1 NACHT domain Syntaxin PF00804.20 ETO00311.1 - 0.029 14.5 1.8 2.3 8.4 0.3 2.3 2 0 0 2 2 2 0 Syntaxin Syntaxin-18_N PF10496.4 ETO00311.1 - 0.049 13.4 1.0 0.087 12.6 0.7 1.5 1 1 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus Ly49 PF08391.5 ETO00311.1 - 3.2 7.8 6.1 4 7.5 3.8 1.5 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region FAA_hydrolase_N PF09298.6 ETO00313.1 - 0.084 12.8 0.6 0.24 11.4 0.4 1.8 1 1 0 1 1 1 0 Fumarylacetoacetase N-terminal Kelch_6 PF13964.1 ETO00314.1 - 0.014 15.5 1.0 1.6 9.0 0.1 3.2 3 0 0 3 3 3 0 Kelch motif WD40 PF00400.27 ETO00315.1 - 1.7e-31 106.9 16.5 6.9e-09 35.2 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Mitofilin PF09731.4 ETO00315.1 - 5.8e-09 35.1 9.7 8.3e-09 34.6 6.7 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein CAF-1_p150 PF11600.3 ETO00315.1 - 2.2e-08 33.7 67.6 3.9e-08 32.9 46.9 1.4 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Nup160 PF11715.3 ETO00315.1 - 2.4e-08 32.6 2.5 0.0087 14.2 0.2 3.8 1 1 2 3 3 3 3 Nucleoporin Nup120/160 LMBR1 PF04791.11 ETO00315.1 - 0.0037 15.8 8.5 0.0075 14.9 5.9 1.4 1 0 0 1 1 1 1 LMBR1-like membrane protein Imm21 PF15569.1 ETO00315.1 - 0.017 14.8 2.8 0.79 9.5 0.3 2.9 2 0 0 2 2 2 0 Immunity protein 21 Mem_trans PF03547.13 ETO00315.1 - 0.12 10.6 3.7 0.21 9.8 2.6 1.4 1 0 0 1 1 1 0 Membrane transport protein UPF0560 PF10577.4 ETO00315.1 - 1.3 7.1 20.2 2.4 6.3 14.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF1777 PF08648.7 ETO00315.1 - 1.8 8.2 56.4 3.2 7.4 39.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DUF106 PF01956.11 ETO00315.1 - 4.1 6.8 26.2 5.4e+02 -0.0 15.7 3.5 2 1 0 2 2 2 0 Integral membrane protein DUF106 DUF2372 PF10178.4 ETO00316.1 - 3.6e-08 33.4 0.0 7.5e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2372) zf-LITAF-like PF10601.4 ETO00317.1 - 2.9 7.8 6.2 2 8.3 1.0 2.3 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Glyco_hydro_38C PF07748.8 ETO00318.1 - 2.1e-29 102.6 0.0 2.5e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain WD40 PF00400.27 ETO00319.1 - 9e-37 123.6 18.1 1.3e-09 37.5 0.2 5.6 5 1 1 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO00319.1 - 4e-08 31.8 4.0 0.013 13.7 0.0 3.2 1 1 1 3 3 3 3 Nucleoporin Nup120/160 YkyA PF10368.4 ETO00321.1 - 1.8 7.8 12.7 0.16 11.3 1.6 2.7 2 1 0 2 2 2 0 Putative cell-wall binding lipoprotein DASH_Ask1 PF08655.5 ETO00322.1 - 0.0086 15.8 1.1 0.03 14.1 0.3 2.2 2 0 0 2 2 2 1 DASH complex subunit Ask1 GlutR_dimer PF00745.15 ETO00322.1 - 0.15 12.0 2.7 0.51 10.3 0.1 2.5 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Phospholip_A2_2 PF05826.7 ETO00322.1 - 2.7 8.0 7.4 8.3 6.4 0.1 3.4 4 0 0 4 4 4 0 Phospholipase A2 Glutaredoxin2_C PF04399.8 ETO00323.1 - 0.022 14.3 1.1 0.042 13.4 0.0 1.9 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain TipAS PF07739.8 ETO00323.1 - 0.1 12.9 0.7 0.18 12.1 0.5 1.5 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain EssA PF10661.4 ETO00324.1 - 0.12 12.0 0.2 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA Lip_A_acyltrans PF03279.8 ETO00325.1 - 0.1 11.4 1.3 0.15 10.9 0.9 1.2 1 0 0 1 1 1 0 Bacterial lipid A biosynthesis acyltransferase ALMT PF11744.3 ETO00325.1 - 4.9 5.7 7.4 0.68 8.5 2.5 1.4 2 0 0 2 2 2 0 Aluminium activated malate transporter RabGAP-TBC PF00566.13 ETO00326.1 - 0.0021 17.5 0.0 0.0021 17.5 0.0 2.1 1 1 0 2 2 2 1 Rab-GTPase-TBC domain Amidase PF01425.16 ETO00327.1 - 3.7e-28 98.5 0.1 1.3e-27 96.7 0.0 1.7 2 0 0 2 2 2 1 Amidase DUF588 PF04535.7 ETO00327.1 - 0.046 13.2 0.3 0.19 11.3 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF588) Adeno_GP19K PF04881.8 ETO00327.1 - 0.062 13.0 0.4 0.096 12.4 0.3 1.3 1 0 0 1 1 1 0 Adenovirus GP19K Eapp_C PF10238.4 ETO00328.1 - 1 9.2 11.3 0.37 10.6 0.2 2.4 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF745 PF05335.8 ETO00329.1 - 0.11 11.9 0.2 0.19 11.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Acetyltransf_1 PF00583.19 ETO00331.1 - 9.7e-11 41.5 0.0 1.6e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETO00331.1 - 7.8e-06 25.9 0.2 4.9e-05 23.4 0.2 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETO00331.1 - 0.00025 20.9 0.0 0.086 12.6 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 ETO00331.1 - 0.00031 20.6 0.0 0.00049 19.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain s48_45 PF07422.8 ETO00331.1 - 0.0042 17.1 1.8 0.036 14.1 0.2 2.2 1 1 1 2 2 2 1 Sexual stage antigen s48/45 domain Acetyltransf_3 PF13302.1 ETO00331.1 - 0.0076 16.4 0.0 0.019 15.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETO00331.1 - 0.035 14.2 0.0 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETO00331.1 - 0.041 13.6 0.0 0.096 12.4 0.0 1.6 2 0 0 2 2 2 0 FR47-like protein SET PF00856.23 ETO00332.1 - 1.1e-06 29.0 0.4 1.8e-05 25.1 0.3 2.3 1 1 0 1 1 1 1 SET domain RasGAP PF00616.14 ETO00332.1 - 0.0039 16.8 0.2 0.0077 15.9 0.1 1.6 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase DUF1886 PF09171.5 ETO00332.1 - 0.008 15.2 3.3 0.2 10.6 0.7 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF1886) Chromo PF00385.19 ETO00333.1 - 8e-06 25.4 0.1 2e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 ETO00333.1 - 0.041 13.5 7.2 0.18 11.5 5.0 2.1 1 1 0 1 1 1 0 PHD-finger DUF4094 PF13334.1 ETO00333.1 - 0.14 12.5 2.2 0.25 11.7 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) DUF912 PF06024.7 ETO00333.1 - 0.2 11.7 2.1 0.35 10.9 1.4 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) BAF1_ABF1 PF04684.8 ETO00333.1 - 0.44 9.3 9.8 0.25 10.1 5.4 1.5 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF1816 PF08846.5 ETO00334.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1816) Sulfolobus_pRN PF05584.6 ETO00335.1 - 0.044 13.7 0.7 0.08 12.9 0.5 1.4 1 0 0 1 1 1 0 Sulfolobus plasmid regulatory protein S-antigen PF05756.6 ETO00335.1 - 2.6 8.0 7.2 0.72 9.8 0.2 2.3 1 1 1 2 2 2 0 S-antigen protein Exo_endo_phos_2 PF14529.1 ETO00336.1 - 2e-07 30.6 1.0 5e-07 29.3 0.7 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase TnpW PF14202.1 ETO00340.1 - 0.074 12.6 0.1 0.19 11.3 0.1 1.7 1 0 0 1 1 1 0 Transposon-encoded protein TnpW UCH PF00443.24 ETO00341.1 - 1.5e-12 47.2 0.8 5e-12 45.4 0.5 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO00341.1 - 0.00068 19.1 0.5 0.0015 18.0 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase YoqO PF14037.1 ETO00341.1 - 5.4 7.1 9.4 0.35 10.9 2.2 2.2 3 0 0 3 3 3 0 YoqO-like protein HSP70 PF00012.15 ETO00342.1 - 1.9e-33 115.2 4.3 3.8e-21 74.6 0.0 2.1 1 1 1 2 2 2 2 Hsp70 protein RNase_PH_C PF03725.10 ETO00342.1 - 0.069 13.0 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 HemY_N PF07219.8 ETO00343.1 - 0.075 12.5 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 HemY protein N-terminus Proteasom_Rpn13 PF04683.8 ETO00344.1 - 0.089 12.8 0.2 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 Proteasome complex subunit Rpn13 ubiquitin receptor DIOX_N PF14226.1 ETO00345.1 - 2.8e-06 27.8 0.0 4.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal FAM176 PF14851.1 ETO00347.1 - 0.86 9.2 15.8 0.43 10.2 6.0 2.1 2 0 0 2 2 2 0 FAM176 family DUF4637 PF15470.1 ETO00347.1 - 5.3 6.6 7.1 0.34 10.5 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) TLD PF07534.11 ETO00348.1 - 2.6e-21 76.0 6.2 1.2e-20 73.8 0.7 2.2 2 0 0 2 2 2 2 TLD FBPase_2 PF06874.6 ETO00348.1 - 0.04 11.9 0.2 0.054 11.5 0.1 1.1 1 0 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase DUF2360 PF10152.4 ETO00349.1 - 3.3e-07 30.6 12.4 8.4e-07 29.3 0.2 3.0 3 0 0 3 3 3 2 Predicted coiled-coil domain-containing protein (DUF2360) PXT1 PF15214.1 ETO00349.1 - 0.0018 18.4 0.2 2.8 8.2 0.0 2.1 2 0 0 2 2 2 2 Peroxisomal testis-specific protein 1 Ribosomal_60s PF00428.14 ETO00349.1 - 0.0029 17.9 8.1 0.38 11.1 1.7 2.2 2 0 0 2 2 2 2 60s Acidic ribosomal protein DUF2974 PF11187.3 ETO00349.1 - 0.034 13.4 0.1 1 8.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF4415 PF14384.1 ETO00349.1 - 0.059 13.5 0.9 13 5.9 0.1 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF4415) EppA_BapA PF07268.6 ETO00349.1 - 0.064 12.9 0.1 9.6 5.8 0.0 2.1 2 0 0 2 2 2 0 Exported protein precursor (EppA/BapA) TonB_2 PF13103.1 ETO00349.1 - 0.098 12.7 1.0 1.8 8.6 0.1 2.3 2 1 0 2 2 2 0 TonB C terminal Renin_r PF07850.9 ETO00349.1 - 1.2 9.5 5.7 10 6.5 0.5 2.2 2 0 0 2 2 2 0 Renin receptor-like protein ASFV_J13L PF05568.6 ETO00349.1 - 1.7 8.1 8.2 1.4 8.4 0.8 2.0 1 1 1 2 2 2 0 African swine fever virus J13L protein Kelch_1 PF01344.20 ETO00351.1 - 7e-09 35.0 4.0 1e-05 24.9 0.4 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO00351.1 - 1.2e-08 34.6 2.3 0.0024 17.5 0.1 4.8 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO00351.1 - 4.2e-07 29.8 8.7 0.0062 16.6 0.2 5.0 3 2 1 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO00351.1 - 9.8e-07 28.7 0.0 0.03 14.5 0.0 3.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO00351.1 - 0.00045 20.1 3.2 2.9 7.9 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO00351.1 - 0.0011 18.6 1.4 0.3 10.9 0.2 3.6 4 0 0 4 4 4 1 Kelch motif DUF2415 PF10313.4 ETO00351.1 - 0.0066 16.0 0.0 0.08 12.6 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) DUF1796 PF08795.5 ETO00351.1 - 0.033 13.8 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) PUB PF09409.5 ETO00352.1 - 0.039 13.7 2.1 0.057 13.1 0.7 2.0 2 1 0 2 2 2 0 PUB domain DSPc PF00782.15 ETO00353.1 - 3.5e-25 88.1 1.1 3.7e-22 78.3 0.2 2.9 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 ETO00353.1 - 7.7e-05 22.7 0.1 0.0001 22.4 0.0 1.3 1 1 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 ETO00353.1 - 0.00086 18.7 0.4 0.0016 17.8 0.3 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 ETO00353.1 - 0.016 14.1 0.1 0.024 13.5 0.1 1.3 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase GABP-alpha PF11620.3 ETO00354.1 - 0.051 13.5 0.3 0.14 12.1 0.2 1.7 1 0 0 1 1 1 0 GA-binding protein alpha chain SRI PF08236.6 ETO00354.1 - 0.96 9.4 5.1 0.71 9.8 0.2 3.1 3 1 1 4 4 4 0 SRI (Set2 Rpb1 interacting) domain ZZ PF00569.12 ETO00357.1 - 7.1e-15 54.2 8.0 2.1e-14 52.7 5.6 1.9 1 0 0 1 1 1 1 Zinc finger, ZZ type zf-B_box PF00643.19 ETO00357.1 - 0.027 14.3 6.4 0.088 12.7 4.5 1.9 1 0 0 1 1 1 0 B-box zinc finger EndIII_4Fe-2S PF10576.4 ETO00357.1 - 2.3 8.5 8.4 7 7.0 0.5 3.7 3 0 0 3 3 3 0 Iron-sulfur binding domain of endonuclease III C1_3 PF07649.7 ETO00357.1 - 2.7 8.1 9.6 8.8 6.4 6.6 2.0 1 0 0 1 1 1 0 C1-like domain Desulfoferrod_N PF06397.7 ETO00357.1 - 3.1 7.2 9.8 0.47 9.8 1.1 2.7 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain SPX PF03105.14 ETO00358.1 - 3.6e-06 26.9 0.8 7e-06 26.0 0.5 1.5 1 1 0 1 1 1 1 SPX domain Ca_hom_mod PF14798.1 ETO00358.1 - 0.016 14.1 2.8 0.088 11.7 0.0 2.2 2 0 0 2 2 2 0 Calcium homeostasis modulator Pkinase PF00069.20 ETO00359.1 - 2.6e-23 82.5 0.0 3.1e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO00359.1 - 0.0019 17.3 0.1 0.0032 16.5 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase 2OG-FeII_Oxy_2 PF13532.1 ETO00359.1 - 0.081 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily SID-1_RNA_chan PF13965.1 ETO00360.1 - 3.5 5.6 11.5 2.2 6.3 0.6 1.7 1 1 1 2 2 2 0 dsRNA-gated channel SID-1 COMP PF11598.3 ETO00361.1 - 0.01 15.8 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein PH_5 PF15405.1 ETO00361.1 - 0.057 13.3 2.5 0.081 12.8 0.6 2.0 1 1 0 2 2 2 0 Pleckstrin homology domain Menin PF05053.8 ETO00361.1 - 0.2 9.7 5.4 0.31 9.1 3.7 1.2 1 0 0 1 1 1 0 Menin LLC1 PF14945.1 ETO00361.1 - 0.93 9.8 4.3 2.2 8.5 0.7 2.3 1 1 1 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein 120_Rick_ant PF12574.3 ETO00362.1 - 0.096 11.7 0.0 0.11 11.6 0.0 1.0 1 0 0 1 1 1 0 120 KDa Rickettsia surface antigen Herpes_IE2_3 PF03361.9 ETO00362.1 - 0.096 12.0 0.5 0.11 11.8 0.3 1.1 1 0 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 RLL PF10036.4 ETO00362.1 - 0.11 11.8 0.4 0.13 11.6 0.3 1.1 1 0 0 1 1 1 0 Putative carnitine deficiency-associated protein TPR_12 PF13424.1 ETO00364.1 - 1.2e-26 92.4 1.4 1.6e-18 66.4 0.8 1.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO00364.1 - 1.6e-14 53.2 0.0 8.1e-08 31.9 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO00364.1 - 2.5e-14 52.1 9.0 3.9e-09 35.7 3.2 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO00364.1 - 2.7e-13 48.6 0.4 7.1e-08 31.6 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO00364.1 - 1.7e-12 46.8 1.4 3e-12 46.0 1.0 1.3 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 ETO00364.1 - 8.5e-11 40.9 5.7 8e-07 28.5 1.5 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO00364.1 - 6.3e-09 34.9 7.1 3.6e-06 26.3 2.3 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO00364.1 - 7.1e-06 25.8 0.2 0.0045 17.0 0.1 2.5 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO00364.1 - 0.00039 20.9 0.0 0.0018 18.9 0.0 1.6 1 1 1 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO00364.1 - 0.0019 18.0 3.2 0.033 14.0 0.5 2.1 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 ETO00364.1 - 0.014 15.8 0.2 2.1 9.0 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETO00364.1 - 0.025 15.2 0.0 4.6 8.1 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.15 ETO00364.1 - 0.033 14.1 0.1 2.8 8.1 0.1 2.3 2 0 0 2 2 2 0 PPR repeat MIT PF04212.13 ETO00364.1 - 0.11 12.3 4.4 0.93 9.4 0.8 2.2 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain DUF962 PF06127.6 ETO00364.1 - 0.17 11.7 1.7 0.3 10.9 0.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF962) Arm PF00514.18 ETO00365.1 - 6.7e-15 54.2 1.1 0.0052 16.5 0.0 6.1 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 ETO00365.1 - 1.9e-05 24.8 0.1 0.00018 21.7 0.0 2.8 3 1 0 3 3 3 1 HEAT repeats HEAT PF02985.17 ETO00365.1 - 0.0022 17.9 0.0 2.7 8.3 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 ETO00365.1 - 0.011 16.1 0.1 1.3 9.5 0.0 4.1 4 1 2 6 6 6 0 HEAT-like repeat RICTOR_V PF14668.1 ETO00365.1 - 0.019 14.8 0.5 0.37 10.7 0.0 3.2 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 TPR_12 PF13424.1 ETO00367.1 - 3e-40 136.0 4.5 7.4e-21 73.8 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO00367.1 - 9.5e-30 100.9 23.2 2.6e-10 39.4 2.1 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO00367.1 - 2.3e-29 100.8 10.6 4.3e-15 55.1 1.7 3.1 3 0 0 3 3 3 3 TPR repeat TPR_2 PF07719.12 ETO00367.1 - 1.8e-26 89.8 14.8 5.4e-08 32.1 1.4 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO00367.1 - 5.2e-26 89.7 0.0 6.9e-11 41.7 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO00367.1 - 4.7e-24 82.2 3.0 8.3e-08 31.4 0.1 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO00367.1 - 7.3e-24 81.7 22.7 5.1e-09 35.2 1.7 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO00367.1 - 1.1e-14 53.5 0.0 0.0017 18.8 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO00367.1 - 7.7e-12 45.5 0.2 3.7e-07 30.6 0.1 2.7 2 1 0 3 3 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO00367.1 - 1.2e-10 41.1 5.2 0.018 15.4 0.2 4.6 4 1 0 4 4 4 3 Tetratricopeptide repeat SNAP PF14938.1 ETO00367.1 - 6.6e-10 38.5 6.8 7.9e-09 35.0 4.7 2.0 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP SHNi-TPR PF10516.4 ETO00367.1 - 1.2e-08 33.9 2.8 0.033 13.4 0.0 3.5 3 0 0 3 3 3 3 SHNi-TPR MIT PF04212.13 ETO00367.1 - 1.4e-08 34.5 9.4 0.15 11.9 0.4 4.3 4 0 0 4 4 4 3 MIT (microtubule interacting and transport) domain TPR_17 PF13431.1 ETO00367.1 - 1.2e-06 28.1 13.5 0.00038 20.4 0.7 5.2 5 2 0 5 5 4 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO00367.1 - 4.5e-06 26.6 13.7 0.0022 18.1 3.3 3.2 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO00367.1 - 5e-06 26.7 5.8 0.008 16.4 0.8 3.0 2 1 0 3 3 3 2 Tetratricopeptide repeat DUF2225 PF09986.4 ETO00367.1 - 7e-06 25.6 12.8 0.0021 17.5 5.4 3.1 1 1 2 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) Sel1 PF08238.7 ETO00367.1 - 2.3e-05 24.8 8.8 0.23 12.1 0.5 4.2 4 0 0 4 4 4 2 Sel1 repeat PPR PF01535.15 ETO00367.1 - 0.0022 17.8 4.6 6.5 6.9 0.2 4.1 4 0 0 4 4 4 0 PPR repeat DUF627 PF04781.7 ETO00367.1 - 0.019 14.5 4.0 0.19 11.3 0.0 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF627) TPR_9 PF13371.1 ETO00367.1 - 0.021 14.6 0.1 10 6.0 0.0 2.9 3 1 0 3 3 2 0 Tetratricopeptide repeat Glyoxalase_2 PF12681.2 ETO00367.1 - 0.023 15.2 0.0 2.4 8.8 0.0 2.6 1 1 0 1 1 1 0 Glyoxalase-like domain RPN7 PF10602.4 ETO00367.1 - 0.026 13.9 10.6 2.5 7.4 0.9 3.5 2 2 2 4 4 4 0 26S proteasome subunit RPN7 OEP PF02321.13 ETO00367.1 - 0.038 13.5 2.1 4.9 6.7 0.2 2.3 2 1 0 2 2 2 0 Outer membrane efflux protein NSF PF02071.15 ETO00367.1 - 0.045 14.2 13.3 13 6.8 0.0 5.0 4 0 0 4 4 4 0 Aromatic-di-Alanine (AdAR) repeat ATP-synt_E_2 PF08112.6 ETO00367.1 - 0.091 12.8 2.6 7.6 6.6 0.1 3.1 3 0 0 3 3 3 0 ATP synthase epsilon subunit DUF3856 PF12968.2 ETO00367.1 - 0.1 12.4 1.3 0.32 10.7 0.2 2.1 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) SPO22 PF08631.5 ETO00367.1 - 0.12 11.4 10.3 0.28 10.2 2.7 3.0 2 2 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like TPR_3 PF07720.7 ETO00367.1 - 0.12 12.1 16.2 0.57 10.0 0.4 3.8 4 1 1 5 5 5 0 Tetratricopeptide repeat Ubiq-assoc PF09145.5 ETO00367.1 - 0.16 11.8 4.3 17 5.3 0.2 3.7 4 0 0 4 4 3 0 Ubiquitin-associated Sec5 PF15469.1 ETO00367.1 - 0.26 10.9 8.2 1.8 8.2 0.2 2.9 2 1 0 2 2 2 0 Exocyst complex component Sec5 NYD-SP28_assoc PF14775.1 ETO00367.1 - 0.48 10.1 4.7 5.3 6.8 0.1 3.2 3 0 0 3 3 3 0 Sperm tail C-terminal domain Phage_Gp111 PF07410.6 ETO00367.1 - 0.52 10.4 6.4 0.75 9.9 0.0 3.4 2 1 2 4 4 4 0 Streptococcus thermophilus bacteriophage Gp111 protein MscS_porin PF12795.2 ETO00367.1 - 0.73 9.1 2.7 0.82 8.9 0.3 1.9 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Clathrin PF00637.15 ETO00367.1 - 1.1 8.8 8.4 6.9 6.2 0.4 3.0 2 1 0 3 3 2 0 Region in Clathrin and VPS UVR PF02151.14 ETO00367.1 - 1.4 8.5 6.8 14 5.3 0.0 3.8 3 1 1 4 4 4 0 UvrB/uvrC motif TFIIS_M PF07500.9 ETO00367.1 - 1.7 8.7 6.2 5.9 6.9 0.1 2.4 2 1 0 2 2 2 0 Transcription factor S-II (TFIIS), central domain TPR_21 PF09976.4 ETO00367.1 - 5.8 6.8 6.8 2.2 8.1 0.7 2.5 3 0 0 3 3 2 0 Tetratricopeptide repeat Peptidase_C28 PF05408.6 ETO00368.1 - 0.038 13.4 0.4 0.052 13.0 0.3 1.2 1 0 0 1 1 1 0 Foot-and-mouth virus L-proteinase OST-HTH PF12872.2 ETO00369.1 - 0.07 12.9 0.1 0.15 11.8 0.0 1.5 2 0 0 2 2 2 0 OST-HTH/LOTUS domain POX PF07526.6 ETO00369.1 - 0.53 10.5 4.4 21 5.3 0.0 2.2 2 0 0 2 2 2 0 Associated with HOX Menin PF05053.8 ETO00369.1 - 0.62 8.1 4.1 0.6 8.2 2.8 1.2 1 0 0 1 1 1 0 Menin Macoilin PF09726.4 ETO00369.1 - 1.6 6.8 9.5 1.8 6.7 6.6 1.2 1 0 0 1 1 1 0 Transmembrane protein ABC2_membrane_3 PF12698.2 ETO00369.1 - 2.6 6.9 8.1 3.1 6.7 5.6 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein RAP1 PF07218.6 ETO00369.1 - 3.4 5.6 8.8 3.8 5.4 6.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Kelch_4 PF13418.1 ETO00370.1 - 2.5e-06 27.1 0.2 0.022 14.4 0.0 2.4 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO00370.1 - 9.3e-06 25.5 0.9 0.0038 17.3 0.3 2.5 1 1 1 2 2 2 2 Kelch motif Kelch_2 PF07646.10 ETO00370.1 - 1.1e-05 24.9 0.3 0.023 14.4 0.2 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 ETO00370.1 - 0.001 19.1 0.0 0.0069 16.5 0.0 2.3 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO00370.1 - 0.0014 18.1 0.7 0.014 14.9 0.2 2.3 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.1 ETO00370.1 - 0.19 11.7 0.9 0.52 10.3 0.6 1.7 2 0 0 2 2 2 0 Kelch motif BSP_II PF05432.6 ETO00371.1 - 0.0008 18.7 10.4 0.0011 18.3 7.2 1.3 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) CENP-B_dimeris PF09026.5 ETO00371.1 - 0.0011 19.1 10.1 0.0015 18.7 7.0 1.2 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Radial_spoke PF04712.7 ETO00371.1 - 0.0017 17.2 7.5 0.0017 17.2 5.2 1.0 1 0 0 1 1 1 1 Radial spokehead-like protein CDV3 PF15359.1 ETO00371.1 - 0.0028 17.7 1.0 0.0035 17.4 0.7 1.1 1 0 0 1 1 1 1 Carnitine deficiency-associated protein 3 FAM176 PF14851.1 ETO00371.1 - 0.0031 17.2 0.2 0.0037 16.9 0.1 1.3 1 0 0 1 1 1 1 FAM176 family Spore_coat_CotO PF14153.1 ETO00371.1 - 0.0034 16.8 1.2 0.0034 16.8 0.8 1.1 1 0 0 1 1 1 1 Spore coat protein CotO SpoIIIAH PF12685.2 ETO00371.1 - 0.0065 15.9 0.0 0.0065 15.9 0.0 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein DUF4366 PF14283.1 ETO00371.1 - 0.009 15.4 0.9 0.01 15.3 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) FAM177 PF14774.1 ETO00371.1 - 0.01 15.7 3.6 0.013 15.4 2.5 1.2 1 0 0 1 1 1 0 FAM177 family Ycf1 PF05758.7 ETO00371.1 - 0.013 13.2 0.9 0.015 13.0 0.6 1.0 1 0 0 1 1 1 0 Ycf1 TRAP_alpha PF03896.11 ETO00371.1 - 0.015 14.3 4.4 0.021 13.8 3.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RNA_pol_Rpc4 PF05132.9 ETO00371.1 - 0.017 15.1 1.2 0.022 14.7 0.8 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Med17 PF10156.4 ETO00371.1 - 0.024 12.9 1.9 0.026 12.7 1.3 1.0 1 0 0 1 1 1 0 Subunit 17 of Mediator complex DUF4484 PF14831.1 ETO00371.1 - 0.051 13.6 0.2 0.052 13.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) DUF1510 PF07423.6 ETO00371.1 - 0.057 12.7 6.8 0.07 12.4 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Prog_receptor PF02161.10 ETO00371.1 - 0.061 12.1 0.7 0.054 12.3 0.5 1.1 1 0 0 1 1 1 0 Progesterone receptor SDA1 PF05285.7 ETO00371.1 - 0.072 12.3 6.6 0.071 12.3 4.6 1.1 1 0 0 1 1 1 0 SDA1 DUF3591 PF12157.3 ETO00371.1 - 0.078 11.3 0.7 0.084 11.2 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3591) Sigma70_ner PF04546.8 ETO00371.1 - 0.089 12.3 10.6 0.12 11.9 7.4 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region TEX19 PF15553.1 ETO00371.1 - 0.095 12.5 1.8 0.097 12.5 1.2 1.1 1 0 0 1 1 1 0 Testis-expressed protein 19 MYCBPAP PF14646.1 ETO00371.1 - 0.098 11.3 1.5 0.099 11.3 1.0 1.0 1 0 0 1 1 1 0 MYCBP-associated protein family DUF3530 PF12048.3 ETO00371.1 - 0.12 11.3 0.2 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) VID27 PF08553.5 ETO00371.1 - 0.13 10.4 7.7 0.13 10.4 5.4 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Trypan_PARP PF05887.6 ETO00371.1 - 0.15 11.9 14.3 0.2 11.4 9.9 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Nop14 PF04147.7 ETO00371.1 - 0.15 9.9 11.1 0.16 9.8 7.7 1.0 1 0 0 1 1 1 0 Nop14-like family Conotoxin PF02950.12 ETO00371.1 - 0.15 12.8 0.0 0.24 12.2 0.0 1.3 1 0 0 1 1 1 0 Conotoxin Leo1 PF04004.8 ETO00371.1 - 0.19 11.4 2.0 0.23 11.1 1.4 1.1 1 0 0 1 1 1 0 Leo1-like protein OAD_gamma PF04277.8 ETO00371.1 - 0.19 12.0 4.9 0.28 11.5 3.4 1.4 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain XAP5 PF04921.9 ETO00371.1 - 0.22 11.0 2.7 0.24 10.9 1.9 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator Tim54 PF11711.3 ETO00371.1 - 0.4 9.2 3.6 0.46 9.0 2.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 YqfQ PF14181.1 ETO00371.1 - 0.76 9.7 5.6 1 9.3 3.9 1.2 1 0 0 1 1 1 0 YqfQ-like protein DUF2890 PF11081.3 ETO00371.1 - 1.2 9.1 13.9 1.5 8.8 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Adeno_terminal PF02459.10 ETO00371.1 - 2 6.5 8.6 2.3 6.3 6.0 1.0 1 0 0 1 1 1 0 Adenoviral DNA terminal protein RXT2_N PF08595.6 ETO00371.1 - 2.7 7.7 8.2 3.6 7.3 5.7 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Pox_RNA_Pol_19 PF05320.7 ETO00371.1 - 4.6 6.9 10.1 6.3 6.5 7.0 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit BUD22 PF09073.5 ETO00371.1 - 5.3 6.0 10.9 6.6 5.6 7.6 1.1 1 0 0 1 1 1 0 BUD22 DUF3381 PF11861.3 ETO00371.1 - 6.9 6.1 14.3 9 5.7 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Nucleoplasmin PF03066.10 ETO00371.1 - 7.7 6.0 22.8 12 5.4 15.8 1.2 1 0 0 1 1 1 0 Nucleoplasmin SlyX PF04102.7 ETO00372.1 - 0.032 14.6 0.2 0.036 14.4 0.1 1.1 1 0 0 1 1 1 0 SlyX GCR1_C PF12550.3 ETO00372.1 - 0.034 14.0 2.4 0.039 13.8 1.6 1.1 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes Pox_A_type_inc PF04508.7 ETO00372.1 - 0.051 13.3 0.9 0.11 12.3 0.4 1.8 1 1 0 1 1 1 0 Viral A-type inclusion protein repeat Seryl_tRNA_N PF02403.17 ETO00372.1 - 0.052 13.5 3.7 0.05 13.6 2.5 1.0 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain PspB PF06667.7 ETO00372.1 - 0.072 13.0 0.7 0.082 12.8 0.5 1.1 1 0 0 1 1 1 0 Phage shock protein B IncA PF04156.9 ETO00372.1 - 0.088 12.4 1.2 0.089 12.3 0.8 1.0 1 0 0 1 1 1 0 IncA protein DUF1798 PF08807.5 ETO00372.1 - 0.11 12.2 0.8 0.11 12.2 0.6 1.0 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) DUF1640 PF07798.6 ETO00372.1 - 0.12 12.4 2.4 0.13 12.3 1.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Snapin_Pallidin PF14712.1 ETO00372.1 - 0.12 12.6 0.4 0.14 12.5 0.3 1.1 1 0 0 1 1 1 0 Snapin/Pallidin PspA_IM30 PF04012.7 ETO00372.1 - 0.13 11.6 2.4 0.15 11.4 1.7 1.0 1 0 0 1 1 1 0 PspA/IM30 family FlxA PF14282.1 ETO00372.1 - 0.17 11.8 1.2 0.21 11.5 0.8 1.3 1 1 0 1 1 1 0 FlxA-like protein DivIC PF04977.10 ETO00372.1 - 0.25 10.8 2.6 0.31 10.5 1.8 1.1 1 0 0 1 1 1 0 Septum formation initiator Kinetocho_Slk19 PF12709.2 ETO00372.1 - 0.56 10.3 5.0 0.59 10.2 3.4 1.1 1 0 0 1 1 1 0 Central kinetochore-associated CCDC-167 PF15188.1 ETO00372.1 - 0.89 9.5 3.5 0.93 9.4 2.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Ax_dynein_light PF10211.4 ETO00372.1 - 0.95 9.2 4.6 0.97 9.2 3.2 1.0 1 0 0 1 1 1 0 Axonemal dynein light chain THOC7 PF05615.8 ETO00372.1 - 1.1 9.4 5.0 1.2 9.3 3.5 1.0 1 0 0 1 1 1 0 Tho complex subunit 7 PEARLI-4 PF05278.7 ETO00372.1 - 4.3 6.6 8.2 4.5 6.5 5.7 1.0 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) HSP70 PF00012.15 ETO00373.1 - 7.9e-09 33.9 0.2 0.0011 16.9 0.1 2.4 2 1 1 3 3 3 2 Hsp70 protein DUF1374 PF07118.6 ETO00374.1 - 0.0084 16.1 1.1 0.015 15.4 0.7 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1374) Peptidase_S13 PF02113.10 ETO00374.1 - 0.12 10.8 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family WD40 PF00400.27 ETO00375.1 - 3.5e-06 26.6 4.0 0.00014 21.6 0.9 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat PAN_3 PF08277.7 ETO00375.1 - 0.016 14.8 2.2 0.022 14.3 0.8 1.7 1 1 0 1 1 1 0 PAN-like domain GreA_GreB_N PF03449.10 ETO00376.1 - 0.025 14.6 0.0 0.06 13.4 0.0 1.6 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal WD40 PF00400.27 ETO00377.1 - 2.3e-44 147.6 26.5 9e-11 41.2 0.2 6.3 6 1 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO00377.1 - 1.6e-05 23.2 0.4 1.5 6.8 0.0 3.9 2 1 2 4 4 4 3 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO00377.1 - 0.028 14.3 0.1 0.82 9.6 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3601) TetM_leader PF08076.6 ETO00377.1 - 0.58 9.7 10.4 2 8.0 0.0 4.3 5 0 0 5 5 5 0 Tetracycline resistance determinant leader peptide Cnd1 PF12717.2 ETO00378.1 - 0.0073 16.1 0.5 0.033 14.0 0.1 2.0 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Apc3 PF12895.2 ETO00378.1 - 0.014 15.4 2.1 0.72 10.0 0.0 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO00378.1 - 0.04 14.2 0.5 10 6.5 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF912 PF06024.7 ETO00379.1 - 0.016 15.2 0.1 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2956 PF11169.3 ETO00379.1 - 0.041 13.8 0.0 0.048 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) OATP PF03137.15 ETO00379.1 - 0.046 11.7 0.0 0.051 11.6 0.0 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Serinc PF03348.10 ETO00379.1 - 0.083 11.5 0.2 0.084 11.5 0.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF1626 PF07788.6 ETO00380.1 - 1.6 8.5 4.1 0.75 9.6 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1626) EzrA PF06160.7 ETO00381.1 - 0.00067 17.9 13.2 0.00081 17.6 9.2 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Spc7 PF08317.6 ETO00381.1 - 0.8 8.3 17.3 1.6 7.2 11.7 1.6 1 1 1 2 2 2 0 Spc7 kinetochore protein Nup54 PF13874.1 ETO00381.1 - 1.3 8.6 12.9 1.1 8.8 8.0 1.7 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 TMCO5 PF14992.1 ETO00381.1 - 1.5 7.8 16.0 0.51 9.4 9.1 1.5 1 1 0 1 1 1 0 TMCO5 family TMPIT PF07851.8 ETO00381.1 - 1.6 7.7 14.2 0.12 11.4 2.4 2.0 1 1 1 2 2 2 0 TMPIT-like protein Mnd1 PF03962.10 ETO00381.1 - 2 8.0 21.6 8.2e+02 -0.5 15.0 2.1 1 1 0 1 1 1 0 Mnd1 family DUF1664 PF07889.7 ETO00381.1 - 2.4 7.9 7.1 0.77 9.5 1.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HlyD_2 PF12700.2 ETO00381.1 - 2.7 7.0 12.9 3.5 6.6 9.0 1.2 1 0 0 1 1 1 0 HlyD family secretion protein G-gamma PF00631.17 ETO00381.1 - 2.7 7.7 5.9 5.6 6.7 0.8 2.5 2 0 0 2 2 2 0 GGL domain Lzipper-MIP1 PF14389.1 ETO00381.1 - 3.3 7.8 13.0 0.94 9.6 0.3 2.5 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 CENP-H PF05837.7 ETO00381.1 - 5.6 7.2 18.4 5.1 7.3 3.2 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Atg14 PF10186.4 ETO00381.1 - 8.6 5.1 18.6 19 4.0 12.9 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Fib_alpha PF08702.5 ETO00381.1 - 8.9 6.4 13.8 24 5.0 8.5 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF947 PF06102.7 ETO00383.1 - 4e-09 36.5 28.3 1.5e-08 34.6 19.6 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF947) DUF713 PF05218.9 ETO00383.1 - 0.6 9.8 10.0 0.041 13.5 1.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF713) POTRA_1 PF08478.5 ETO00383.1 - 0.71 9.9 3.3 1.5 8.9 0.2 2.5 2 1 1 3 3 3 0 POTRA domain, FtsQ-type AKAP95 PF04988.7 ETO00383.1 - 3 7.6 15.0 0.78 9.4 3.0 2.3 1 1 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) WD40 PF00400.27 ETO00384.1 - 7.5e-76 247.5 6.3 5.8e-14 51.3 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO00384.1 - 7.2e-08 31.0 2.3 0.48 8.4 0.0 4.4 1 1 3 4 4 4 4 Nucleoporin Nup120/160 PD40 PF07676.7 ETO00384.1 - 4.9e-06 26.0 1.8 0.95 9.2 0.0 4.5 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO00384.1 - 1.4e-05 24.0 6.0 0.26 9.9 0.0 4.8 1 1 2 3 3 3 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO00384.1 - 0.00033 19.0 0.4 0.35 9.1 0.1 2.8 1 1 1 2 2 2 2 Cytochrome D1 heme domain DPPIV_N PF00930.16 ETO00384.1 - 0.0036 15.9 0.2 5.7 5.4 0.0 3.7 1 1 3 4 4 4 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region PQQ_2 PF13360.1 ETO00384.1 - 0.024 14.0 0.1 0.49 9.8 0.1 2.8 1 1 1 2 2 2 0 PQQ-like domain Resistin PF06954.6 ETO00384.1 - 0.042 14.1 5.0 8.3 6.7 0.1 4.3 4 2 2 6 6 6 0 Resistin Proteasome_A_N PF10584.4 ETO00384.1 - 0.073 12.4 1.2 30 4.0 0.0 3.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature DBP10CT PF08147.7 ETO00384.1 - 0.2 11.4 2.4 0.31 10.8 0.1 2.4 2 0 0 2 2 2 0 DBP10CT (NUC160) domain WD40 PF00400.27 ETO00387.1 - 1.4e-31 107.1 7.4 1.7e-09 37.2 0.1 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO00387.1 - 0.00033 19.5 1.9 0.036 12.8 0.1 2.8 1 1 2 3 3 3 3 Nup133 N terminal like Nup160 PF11715.3 ETO00387.1 - 0.00049 18.3 2.8 0.25 9.4 0.4 2.7 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO00387.1 - 0.029 14.0 0.1 0.052 13.2 0.0 1.4 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Cnd2 PF05786.9 ETO00390.1 - 0.00089 17.9 2.7 0.001 17.6 1.9 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 Secretin_N_2 PF07655.8 ETO00390.1 - 0.24 11.8 6.8 0.49 10.8 4.7 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain Methyltransf_12 PF08242.7 ETO00390.1 - 0.81 10.1 9.6 2.2 8.8 0.0 2.2 1 1 0 2 2 2 0 Methyltransferase domain ThiI PF02568.9 ETO00391.1 - 0.13 11.6 1.2 0.21 11.0 0.8 1.3 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) DUF604 PF04646.7 ETO00391.1 - 3.6 6.7 5.9 3.4 6.8 2.9 1.7 1 1 1 2 2 2 0 Protein of unknown function, DUF604 CAF-1_p150 PF11600.3 ETO00393.1 - 0.0019 17.5 41.7 0.0033 16.8 28.9 1.3 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1777 PF08648.7 ETO00393.1 - 0.0023 17.6 23.0 0.0038 16.9 15.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) Vfa1 PF08432.5 ETO00393.1 - 0.013 15.5 32.7 0.022 14.7 22.6 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SprA-related PF12118.3 ETO00393.1 - 0.013 14.8 17.7 0.015 14.6 12.3 1.1 1 0 0 1 1 1 0 SprA-related family DUF1510 PF07423.6 ETO00393.1 - 0.067 12.5 27.1 0.089 12.1 18.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RR_TM4-6 PF06459.7 ETO00393.1 - 0.091 12.6 19.5 0.12 12.2 13.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.9 ETO00393.1 - 0.11 10.5 21.0 0.13 10.2 14.6 1.1 1 0 0 1 1 1 0 CDC45-like protein U79_P34 PF03064.11 ETO00393.1 - 0.16 11.4 25.8 0.22 11.0 17.9 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Raftlin PF15250.1 ETO00393.1 - 0.45 8.9 15.1 0.51 8.7 10.4 1.1 1 0 0 1 1 1 0 Raftlin DUF2201_N PF13203.1 ETO00393.1 - 0.62 9.1 12.9 0.79 8.8 8.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Ax_dynein_light PF10211.4 ETO00393.1 - 1 9.1 24.5 1.9 8.3 17.0 1.6 1 0 0 1 1 1 0 Axonemal dynein light chain Rtf2 PF04641.7 ETO00393.1 - 1.4 8.0 26.7 2.1 7.4 18.5 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Parvo_coat PF00740.13 ETO00393.1 - 1.5 7.7 7.7 1.5 7.6 5.3 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP2 MIP-T3 PF10243.4 ETO00393.1 - 1.6 7.1 42.8 2.1 6.7 29.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Hex_IIIa PF02455.11 ETO00393.1 - 2.4 6.7 11.1 2.6 6.6 7.7 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Trypan_PARP PF05887.6 ETO00393.1 - 3.7 7.3 9.9 5.1 6.9 6.9 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Zip PF02535.17 ETO00393.1 - 4.9 6.0 9.9 5.9 5.8 6.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Nucleo_P87 PF07267.6 ETO00393.1 - 5.1 5.6 21.4 6.2 5.3 14.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SID-1_RNA_chan PF13965.1 ETO00393.1 - 8.5 4.4 11.1 9.9 4.1 7.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Myotub-related PF06602.9 ETO00394.1 - 4.7e-54 183.4 1.7 5.3e-54 183.3 1.1 1.0 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain HSP90 PF00183.13 ETO00396.1 - 2.1e-37 128.7 0.2 2.5e-37 128.4 0.2 1.0 1 0 0 1 1 1 1 Hsp90 protein DUF399 PF04187.8 ETO00396.1 - 0.018 14.5 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF399 DUF617 PF04759.8 ETO00397.1 - 0.14 11.7 0.1 0.27 10.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF617 Spore_III_AB PF09548.5 ETO00398.1 - 0.11 12.3 2.5 0.22 11.2 1.7 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) PCI PF01399.22 ETO00398.1 - 0.52 10.6 3.0 0.81 10.0 2.1 1.5 1 1 0 1 1 1 0 PCI domain Mid1 PF12929.2 ETO00399.1 - 0.023 13.4 0.6 0.025 13.3 0.4 1.1 1 0 0 1 1 1 0 Stretch-activated Ca2+-permeable channel component Nop25 PF09805.4 ETO00400.1 - 0.41 10.7 8.4 0.81 9.7 2.7 2.1 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Vfa1 PF08432.5 ETO00400.1 - 0.6 10.1 8.3 0.41 10.6 1.3 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 FAM176 PF14851.1 ETO00400.1 - 1.8 8.1 7.6 0.71 9.5 2.0 2.0 2 0 0 2 2 2 0 FAM176 family Sigma70_ner PF04546.8 ETO00400.1 - 3.8 7.0 17.5 0.018 14.6 3.6 2.1 1 1 1 2 2 2 0 Sigma-70, non-essential region PBP1_TM PF14812.1 ETO00400.1 - 4.7 7.5 19.3 11 6.3 0.4 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glypican PF01153.14 ETO00400.1 - 9.3 4.7 7.4 12 4.3 5.1 1.4 1 1 0 1 1 1 0 Glypican Gemini_C4 PF01492.12 ETO00401.1 - 0.015 14.9 0.1 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Geminivirus C4 protein DUF2663 PF10864.3 ETO00402.1 - 0.19 11.9 0.2 0.19 11.9 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) GTP_EFTU_D3 PF03143.12 ETO00403.1 - 7.5e-12 45.2 0.9 7.9e-11 42.0 0.1 2.6 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 ETO00403.1 - 4.5e-09 36.2 0.0 1.2e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 ETO00403.1 - 5.5e-08 32.3 0.1 1e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Pro_isomerase PF00160.16 ETO00404.1 - 8.8e-42 142.9 0.1 1.1e-41 142.6 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD L27_2 PF09045.5 ETO00405.1 - 0.058 12.9 0.3 0.2 11.1 0.2 2.0 1 0 0 1 1 1 0 L27_2 Branch PF02485.16 ETO00406.1 - 0.017 14.2 0.6 0.024 13.7 0.4 1.2 1 0 0 1 1 1 0 Core-2/I-Branching enzyme PUB PF09409.5 ETO00406.1 - 0.42 10.4 7.6 0.24 11.1 2.1 2.9 3 1 0 3 3 3 0 PUB domain CorA PF01544.13 ETO00408.1 - 0.0075 15.3 3.5 0.0075 15.3 2.4 2.0 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein zf-CCHC PF00098.18 ETO00408.1 - 0.28 11.1 17.0 0.54 10.2 2.2 2.6 2 0 0 2 2 2 0 Zinc knuckle HEAT_2 PF13646.1 ETO00409.1 - 4e-09 36.6 0.0 0.00048 20.3 0.0 2.2 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 ETO00409.1 - 8.4e-09 34.7 0.4 0.11 12.5 0.0 4.1 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 ETO00409.1 - 6.2e-05 23.3 0.0 0.067 13.6 0.0 3.2 2 2 2 4 4 4 1 HEAT-like repeat Adaptin_N PF01602.15 ETO00409.1 - 0.00025 19.4 0.2 0.00031 19.2 0.1 1.2 1 0 0 1 1 1 1 Adaptin N terminal region DUF2435 PF10363.4 ETO00409.1 - 0.00075 19.3 0.3 0.032 14.1 0.1 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF2435) Vac14_Fab1_bd PF12755.2 ETO00409.1 - 0.0018 18.6 1.1 1.6 9.1 0.1 2.4 1 1 2 3 3 3 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 ETO00409.1 - 0.0028 17.5 0.8 0.098 12.5 0.2 2.0 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.5 ETO00409.1 - 0.02 14.4 1.5 2.2 7.8 0.1 2.3 1 1 2 3 3 3 0 TATA-binding protein interacting (TIP20) MSC PF09402.5 ETO00409.1 - 0.039 12.6 0.1 0.046 12.4 0.1 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain MOR2-PAG1_C PF14225.1 ETO00409.1 - 0.043 13.5 0.4 0.11 12.1 0.2 1.8 1 1 0 1 1 1 0 Cell morphogenesis C-terminal DUF3554 PF12074.3 ETO00409.1 - 0.048 13.0 0.5 0.23 10.8 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3554) ENTH PF01417.15 ETO00409.1 - 0.054 13.3 0.2 0.21 11.4 0.1 1.9 1 1 1 2 2 2 0 ENTH domain TFCD_C PF12612.3 ETO00409.1 - 0.082 12.3 0.2 0.13 11.6 0.1 1.5 1 1 0 1 1 1 0 Tubulin folding cofactor D C terminal MSP7_C PF12948.2 ETO00409.1 - 0.088 13.0 1.5 3.3 7.9 0.7 2.7 1 1 1 2 2 2 0 MSP7-like protein C-terminal domain THUMP PF02926.12 ETO00411.1 - 0.04 13.7 4.2 2.2 8.1 0.8 2.5 2 1 0 2 2 2 0 THUMP domain RhoGAP PF00620.22 ETO00411.1 - 0.041 13.4 0.5 0.21 11.2 0.4 2.1 1 1 0 1 1 1 0 RhoGAP domain SAP30_Sin3_bdg PF13867.1 ETO00411.1 - 0.048 13.5 1.5 0.16 11.8 1.0 1.9 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF3452 PF11934.3 ETO00412.1 - 0.053 12.8 0.0 0.053 12.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) UPF0560 PF10577.4 ETO00412.1 - 0.27 9.4 11.0 0.32 9.2 7.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 WD40 PF00400.27 ETO00413.1 - 7.6e-11 41.4 1.7 5.8e-10 38.6 0.1 2.2 2 1 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO00413.1 - 0.081 11.0 0.0 0.081 11.0 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 CHZ PF09649.5 ETO00413.1 - 0.31 10.2 1.7 0.51 9.6 1.2 1.3 1 0 0 1 1 1 0 Histone chaperone domain CHZ Exo_endo_phos_2 PF14529.1 ETO00414.1 - 3e-16 59.0 0.6 5.6e-16 58.2 0.4 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 ETO00414.1 - 0.0085 16.0 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TOMM6 PF15184.1 ETO00415.1 - 0.58 9.5 2.5 6.5 6.1 0.2 2.5 2 0 0 2 2 2 0 Mitochondrial import receptor subunit TOM6 homolog DEP PF00610.16 ETO00416.1 - 1.9e-10 40.3 0.1 3.6e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF3762 PF12591.3 ETO00416.1 - 0.0063 16.5 0.0 0.0098 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3762) Calponin PF00402.13 ETO00416.1 - 0.021 14.1 0.5 0.034 13.4 0.3 1.3 1 0 0 1 1 1 0 Calponin family repeat DEC-1_C PF04626.8 ETO00416.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Dec-1 protein, C terminal region Kelch_2 PF07646.10 ETO00417.1 - 5.8e-05 22.6 0.1 0.00013 21.5 0.1 1.6 1 0 0 1 1 1 1 Kelch motif Kelch_6 PF13964.1 ETO00417.1 - 6.2e-05 22.9 1.1 0.00024 21.1 0.2 2.2 1 1 1 2 2 2 1 Kelch motif Kelch_4 PF13418.1 ETO00417.1 - 0.0032 17.1 0.0 0.0072 16.0 0.0 1.6 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO00417.1 - 0.015 14.8 1.9 0.018 14.5 0.3 2.0 2 0 0 2 2 2 0 Kelch motif GP41 PF00517.12 ETO00418.1 - 0.26 10.8 5.6 3 7.3 1.8 2.4 2 0 0 2 2 2 0 Retroviral envelope protein DUF1765 PF08578.5 ETO00419.1 - 8.5e-09 35.5 3.0 8.5e-09 35.5 2.1 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1765) WD40 PF00400.27 ETO00420.1 - 4.9e-07 29.3 0.1 0.0025 17.6 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat Atg14 PF10186.4 ETO00420.1 - 0.018 14.0 6.7 0.024 13.5 4.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1635 PF07795.6 ETO00420.1 - 0.11 11.8 4.2 0.19 11.0 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) OmpH PF03938.9 ETO00420.1 - 0.69 9.8 13.6 1.2 9.1 9.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SecD-TM1 PF13721.1 ETO00420.1 - 0.98 9.7 3.7 2.8 8.2 2.6 1.7 1 0 0 1 1 1 0 SecD export protein N-terminal TM region PPR_2 PF13041.1 ETO00421.1 - 4.6e-11 42.5 0.0 0.00023 21.0 0.0 2.7 2 0 0 2 2 2 2 PPR repeat family PPR PF01535.15 ETO00421.1 - 7.8e-05 22.3 2.7 0.42 10.6 0.0 4.5 5 0 0 5 5 5 2 PPR repeat PPR_3 PF13812.1 ETO00421.1 - 0.0012 18.9 2.5 2.5 8.6 0.0 4.0 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR_1 PF12854.2 ETO00421.1 - 0.0017 17.7 5.0 0.65 9.5 0.0 4.0 5 0 0 5 5 5 2 PPR repeat MRF_C2 PF13888.1 ETO00421.1 - 0.1 12.3 0.5 0.16 11.7 0.4 1.4 1 1 0 1 1 1 0 Myelin gene regulatory factor C-terminal domain 2 WD40 PF00400.27 ETO00423.1 - 3.4e-66 216.9 11.2 3.4e-14 52.0 0.0 5.0 5 0 0 5 5 5 5 WD domain, G-beta repeat PQQ_2 PF13360.1 ETO00423.1 - 2.3e-11 43.6 0.5 0.00011 21.7 0.1 2.4 1 1 1 2 2 2 2 PQQ-like domain Nup160 PF11715.3 ETO00423.1 - 3e-08 32.2 0.6 0.0042 15.2 0.1 3.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF1258 PF06869.7 ETO00423.1 - 1.6e-07 30.6 0.1 0.34 9.9 0.0 4.0 1 1 3 4 4 4 3 Protein of unknown function (DUF1258) DUF3312 PF11768.3 ETO00423.1 - 1.1e-05 23.9 0.0 0.017 13.3 0.0 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF3312) PD40 PF07676.7 ETO00423.1 - 1.6e-05 24.4 6.3 8.8 6.1 0.0 5.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Me-amine-dh_H PF06433.6 ETO00423.1 - 4e-05 22.4 0.0 0.15 10.6 0.0 2.3 1 1 1 2 2 2 2 Methylamine dehydrogenase heavy chain (MADH) Gmad1 PF10647.4 ETO00423.1 - 4.6e-05 22.9 2.5 0.0016 17.9 0.4 2.4 1 1 1 2 2 2 2 Lipoprotein LpqB beta-propeller domain Cytochrom_D1 PF02239.11 ETO00423.1 - 4.9e-05 21.7 0.9 0.12 10.5 0.0 2.9 1 1 3 4 4 4 4 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 ETO00423.1 - 0.00037 19.7 6.9 17 4.8 0.0 5.3 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Nucleoporin_N PF08801.6 ETO00423.1 - 0.0015 17.3 6.2 2.2 6.9 0.2 3.5 1 1 3 4 4 4 2 Nup133 N terminal like DPPIV_N PF00930.16 ETO00423.1 - 0.0018 16.9 0.2 5.1 5.5 0.0 3.6 1 1 3 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region IKI3 PF04762.7 ETO00423.1 - 0.015 13.1 0.2 0.3 8.8 0.0 1.8 1 1 1 2 2 2 0 IKI3 family DUF4242 PF14026.1 ETO00423.1 - 0.021 14.8 0.0 0.66 10.1 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF4242) TFIIIC_delta PF12657.2 ETO00423.1 - 0.049 13.3 5.1 0.81 9.3 0.6 3.0 1 1 2 3 3 3 0 Transcription factor IIIC subunit delta N-term DUF3732 PF12532.3 ETO00423.1 - 0.067 12.7 1.1 27 4.1 0.0 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF3732) KH_1 PF00013.24 ETO00423.1 - 1.9 8.2 9.7 18 5.0 0.1 4.4 5 0 0 5 5 5 0 KH domain ubiquitin PF00240.18 ETO00424.1 - 4.8e-30 102.7 0.3 5.2e-30 102.6 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 ETO00424.1 - 5.3e-16 58.0 0.2 5.8e-16 57.9 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 ETO00424.1 - 6.3e-06 26.3 0.1 2.8e-05 24.2 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 ETO00424.1 - 0.0014 18.4 0.0 0.0037 17.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 ETO00424.1 - 0.013 15.6 0.1 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 ETO00424.1 - 0.052 13.5 0.0 0.092 12.7 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) YqfQ PF14181.1 ETO00425.1 - 0.0001 22.3 14.9 0.011 15.8 0.0 3.1 3 0 0 3 3 3 3 YqfQ-like protein INT_SG_DDX_CT_C PF15300.1 ETO00426.1 - 0.0055 16.1 0.1 0.015 14.7 0.0 1.7 1 0 0 1 1 1 1 INTS6/SAGE1/DDX26B/CT45 C-terminus YyzF PF14116.1 ETO00426.1 - 0.076 12.9 1.0 17 5.4 0.0 2.8 3 0 0 3 3 3 0 YyzF-like protein MitMem_reg PF13012.1 ETO00428.1 - 0.043 13.8 0.4 0.13 12.3 0.1 1.9 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Glyco_tran_WbsX PF14307.1 ETO00428.1 - 0.092 11.8 3.0 0.15 11.1 2.0 1.4 1 1 0 1 1 1 0 Glycosyltransferase WbsX DUF1191 PF06697.7 ETO00429.1 - 0.02 13.7 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) ArsR PF09824.4 ETO00429.1 - 0.023 13.9 2.7 0.087 12.1 1.5 2.0 2 1 0 2 2 2 0 ArsR transcriptional regulator Na_trans_assoc PF06512.8 ETO00429.1 - 0.026 14.5 2.7 0.03 14.2 1.9 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Calc_CGRP_IAPP PF00214.14 ETO00429.1 - 0.072 13.1 1.4 0.11 12.5 0.9 1.3 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family YajC PF02699.10 ETO00429.1 - 0.22 11.1 1.3 1.6 8.4 0.3 2.4 2 0 0 2 2 2 0 Preprotein translocase subunit zf-CpG_bind_C PF12269.3 ETO00429.1 - 0.35 10.3 3.4 0.48 9.8 2.4 1.2 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain MAT1 PF06391.8 ETO00429.1 - 1.6 8.2 14.7 2.9 7.4 7.0 2.0 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 RIC3 PF15361.1 ETO00429.1 - 3.4 7.8 8.9 1.8 8.7 4.4 1.8 1 1 1 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 NST1 PF13945.1 ETO00429.1 - 3.5 7.6 12.2 2.7 8.0 7.2 1.7 1 1 1 2 2 2 0 Salt tolerance down-regulator DUF4366 PF14283.1 ETO00429.1 - 7.6 5.8 8.4 2.9 7.2 2.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) Cytomega_TRL10 PF06084.6 ETO00430.1 - 1.6 8.5 4.0 3.5 7.4 2.8 1.6 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein Nucleo_P87 PF07267.6 ETO00430.1 - 7.3 5.1 11.7 9.3 4.7 8.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Kelch_1 PF01344.20 ETO00431.1 - 2.4e-08 33.3 9.1 1.9e-05 24.0 0.9 4.4 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 ETO00431.1 - 3.3e-07 30.1 11.4 0.00094 19.2 0.6 4.8 4 2 1 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO00431.1 - 7.6e-06 25.4 5.8 0.013 15.2 0.1 4.9 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO00431.1 - 1.6e-05 24.5 3.5 0.0089 15.7 0.2 3.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO00431.1 - 9.1e-05 22.3 3.7 0.12 12.3 0.3 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO00431.1 - 0.0065 16.6 2.3 0.033 14.3 0.1 3.4 4 0 0 4 4 4 1 Galactose oxidase, central domain DKNYY PF13644.1 ETO00431.1 - 0.015 15.5 5.6 0.042 14.1 3.9 1.7 1 1 0 1 1 1 0 DKNYY family Pol_alpha_B_N PF08418.5 ETO00433.1 - 0.016 14.7 3.8 0.023 14.2 2.7 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal FRG PF08867.6 ETO00433.1 - 0.14 12.6 1.5 0.3 11.6 1.0 1.5 1 0 0 1 1 1 0 FRG domain DUF3951 PF13131.1 ETO00433.1 - 4.1 7.2 7.2 0.61 9.8 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) Cas_CXXC_CXXC PF09706.5 ETO00435.1 - 4.1 7.6 7.1 3.1 8.0 1.3 2.3 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) RXT2_N PF08595.6 ETO00436.1 - 0.13 12.0 12.9 0.4 10.4 7.7 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal Sigma70_ner PF04546.8 ETO00436.1 - 0.29 10.7 10.2 0.46 10.0 7.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 ETO00436.1 - 0.34 10.3 19.8 4 6.9 12.7 2.2 2 0 0 2 2 2 0 Nucleoplasmin DUF2457 PF10446.4 ETO00436.1 - 0.36 9.5 19.1 0.6 8.7 13.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 ETO00436.1 - 0.8 7.6 11.2 1.5 6.7 7.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 ETO00436.1 - 1.2 6.9 12.8 1.5 6.6 8.9 1.1 1 0 0 1 1 1 0 Nop14-like family PBP1_TM PF14812.1 ETO00436.1 - 1.3 9.3 14.2 2.4 8.5 9.8 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Daxx PF03344.10 ETO00436.1 - 1.4 7.2 12.6 1.9 6.8 8.7 1.1 1 0 0 1 1 1 0 Daxx Family FAM176 PF14851.1 ETO00436.1 - 1.9 8.1 5.8 3.4 7.3 4.0 1.3 1 0 0 1 1 1 0 FAM176 family SDA1 PF05285.7 ETO00436.1 - 2.9 7.0 14.3 3.2 6.9 8.7 1.7 2 0 0 2 2 2 0 SDA1 TRAP_alpha PF03896.11 ETO00436.1 - 3.2 6.6 11.6 4.8 6.1 8.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CENP-B_dimeris PF09026.5 ETO00436.1 - 3.4 7.9 18.1 6.3 7.1 12.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF3295 PF11702.3 ETO00436.1 - 7.5 5.4 9.0 9.9 5.0 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) HECT PF00632.20 ETO00437.1 - 1.1e-11 44.4 0.2 1.7e-11 43.8 0.1 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DDHD PF02862.12 ETO00437.1 - 0.32 10.7 3.2 0.46 10.2 2.3 1.3 1 0 0 1 1 1 0 DDHD domain RVT_1 PF00078.22 ETO00440.1 - 0.029 13.7 0.1 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 ETO00441.1 - 4.5e-08 32.7 0.2 6.3e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase COPIIcoated_ERV PF07970.7 ETO00441.1 - 1 8.9 5.4 0.28 10.7 1.6 1.5 2 0 0 2 2 2 0 Endoplasmic reticulum vesicle transporter TPR_12 PF13424.1 ETO00443.1 - 9.7e-14 51.0 0.1 4.5e-08 32.9 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO00443.1 - 2.6e-12 45.7 6.0 1.9e-05 24.0 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO00443.1 - 1.9e-10 40.2 0.5 1.9e-10 40.2 0.3 1.5 2 0 0 2 2 1 1 TPR repeat TPR_8 PF13181.1 ETO00443.1 - 1.1e-09 37.3 3.3 0.00037 20.0 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO00443.1 - 3.8e-09 35.7 1.6 0.0019 17.9 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO00443.1 - 1.9e-07 30.3 0.0 0.00016 21.1 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO00443.1 - 0.00053 19.8 0.0 0.063 13.2 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO00443.1 - 0.0038 17.5 0.4 4.4 7.9 0.1 2.5 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO00443.1 - 0.0046 17.0 0.7 0.86 9.9 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO00443.1 - 0.0093 16.2 0.1 0.032 14.5 0.0 1.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO00443.1 - 0.01 16.4 0.0 5 8.0 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO00443.1 - 0.029 14.2 0.2 0.1 12.4 0.0 1.9 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Apc3 PF12895.2 ETO00443.1 - 0.035 14.2 0.4 0.067 13.3 0.3 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 ETO00443.1 - 0.055 14.1 0.0 0.16 12.7 0.0 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat FHA PF00498.21 ETO00444.1 - 9.3e-11 41.7 0.9 1.4e-10 41.1 0.1 1.6 2 0 0 2 2 2 1 FHA domain DUF677 PF05055.7 ETO00445.1 - 0.00013 20.7 3.7 0.00018 20.3 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF677) RNA_polI_A14 PF08203.6 ETO00445.1 - 0.018 15.2 1.9 0.034 14.3 1.3 1.5 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 UBA_3 PF09288.5 ETO00445.1 - 0.047 13.2 0.0 14 5.4 0.1 2.7 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain ACCA PF03255.9 ETO00445.1 - 0.44 10.0 3.6 0.39 10.2 0.7 1.9 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit GBP_C PF02841.9 ETO00445.1 - 0.76 8.9 8.9 0.83 8.7 6.1 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Kelch_1 PF01344.20 ETO00446.1 - 9.3e-06 25.0 0.2 2.4 7.7 0.1 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 ETO00446.1 - 0.0019 17.9 0.5 3.9 7.3 0.0 4.2 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO00446.1 - 0.0041 17.2 3.2 3 8.1 0.0 4.5 5 1 0 5 5 5 2 Kelch motif ADP_PFK_GK PF04587.10 ETO00447.1 - 0.029 12.6 0.3 0.046 11.9 0.2 1.4 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region zf-C3HC4_2 PF13923.1 ETO00448.1 - 0.11 12.5 2.5 0.62 10.1 1.0 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF904 PF06005.7 ETO00448.1 - 1.6 9.0 8.9 4.1 7.7 6.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF904) zf-RING_2 PF13639.1 ETO00449.1 - 0.0068 16.2 1.6 0.0068 16.2 1.1 2.0 2 0 0 2 2 2 1 Ring finger domain DUF2229 PF09989.4 ETO00449.1 - 0.031 13.7 0.1 0.057 12.8 0.1 1.4 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Paired_CXXCH_1 PF09699.5 ETO00449.1 - 0.046 13.2 0.1 0.14 11.7 0.1 1.9 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) zf-RING_5 PF14634.1 ETO00449.1 - 0.18 11.5 2.9 0.29 10.8 0.4 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-rbx1 PF12678.2 ETO00449.1 - 8.2 6.6 7.9 13 5.9 4.1 2.5 2 1 0 2 2 2 0 RING-H2 zinc finger HEAT PF02985.17 ETO00450.1 - 1.2e-06 28.1 0.5 0.0011 18.8 0.0 4.0 5 1 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 ETO00450.1 - 3.2e-06 27.3 0.0 8.2e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.1 ETO00450.1 - 0.00021 21.6 0.0 0.00094 19.6 0.0 2.0 1 1 2 3 3 3 1 HEAT-like repeat Cnd1 PF12717.2 ETO00450.1 - 0.00046 20.0 0.0 0.00073 19.4 0.0 1.3 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 ETO00450.1 - 0.0019 17.6 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 CLASP N terminal Vac14_Fab1_bd PF12755.2 ETO00450.1 - 0.002 18.4 0.0 0.042 14.2 0.0 2.3 1 1 1 2 2 2 1 Vacuolar 14 Fab1-binding region MOR2-PAG1_N PF14222.1 ETO00450.1 - 0.022 13.4 0.0 3.6 6.1 0.0 2.0 1 1 1 2 2 2 0 Cell morphogenesis N-terminal DUF3944 PF13099.1 ETO00450.1 - 0.042 13.3 1.8 0.67 9.4 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3944) Glyco_hydro_2_C PF02836.12 ETO00451.1 - 6.8e-25 87.5 0.5 1.2e-24 86.7 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 ETO00451.1 - 2.9e-07 30.9 1.3 5.8e-07 29.9 0.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 TPT PF03151.11 ETO00452.1 - 1.7e-16 60.2 8.6 2e-16 60.0 6.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family DUF2569 PF10754.4 ETO00452.1 - 0.036 14.2 3.0 0.065 13.4 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) UAA PF08449.6 ETO00452.1 - 0.036 12.9 6.0 0.042 12.7 4.2 1.1 1 0 0 1 1 1 0 UAA transporter family EamA PF00892.15 ETO00452.1 - 0.18 11.8 8.8 1.1 9.3 6.1 2.2 1 1 0 1 1 1 0 EamA-like transporter family Lipid_DES PF08557.5 ETO00453.1 - 0.011 14.9 0.4 0.61 9.3 0.1 2.3 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) PPR_2 PF13041.1 ETO00455.1 - 8.2e-11 41.7 4.2 6.3e-05 22.8 0.0 3.1 2 1 1 3 3 3 3 PPR repeat family PPR PF01535.15 ETO00455.1 - 1.6e-08 33.9 6.8 0.08 12.9 0.0 3.6 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.1 ETO00455.1 - 6.5e-08 32.2 0.0 0.0072 16.5 0.0 3.3 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 ETO00455.1 - 0.00055 19.3 1.5 1.7 8.2 0.0 3.3 3 0 0 3 3 3 2 PPR repeat ATP13 PF12921.2 ETO00455.1 - 0.18 11.1 2.1 1.1 8.6 0.3 2.5 1 1 2 3 3 3 0 Mitochondrial ATPase expression DEP PF00610.16 ETO00457.1 - 0.0038 16.9 0.0 0.0079 15.9 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Taxilin PF09728.4 ETO00458.1 - 0.00048 19.3 32.7 0.012 14.6 17.9 2.7 1 1 1 2 2 2 1 Myosin-like coiled-coil protein Cortex-I_coil PF09304.5 ETO00458.1 - 0.022 14.8 3.1 0.022 14.8 2.2 3.2 2 1 0 3 3 3 0 Cortexillin I, coiled coil DUF885 PF05960.6 ETO00458.1 - 0.058 12.5 9.5 0.067 12.3 6.6 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) DUF3166 PF11365.3 ETO00458.1 - 0.83 10.1 6.5 1.4 9.4 0.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3166) Phage_1_1 PF08200.6 ETO00458.1 - 1.5 9.0 8.9 1.7 8.9 1.5 2.9 2 1 1 3 3 3 0 Bacteriophage 1.1 Protein DUF1843 PF08898.5 ETO00458.1 - 8.1 6.5 14.3 0.82 9.7 0.1 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) TPR_12 PF13424.1 ETO00459.1 - 1.2e-47 159.7 1.4 6.8e-20 70.7 0.0 3.0 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO00459.1 - 7.5e-29 98.7 0.0 4e-09 36.1 0.0 4.0 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO00459.1 - 2.7e-24 84.5 4.7 5.8e-11 41.8 0.1 3.1 2 1 0 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETO00459.1 - 3.6e-24 83.3 14.1 1.4e-08 33.9 0.2 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO00459.1 - 1.2e-22 77.8 1.6 3.9e-07 29.3 0.0 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO00459.1 - 9.9e-18 62.5 10.0 8e-06 25.3 0.1 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO00459.1 - 1.7e-16 58.6 20.4 7.5e-06 25.3 0.6 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETO00459.1 - 8.3e-12 44.3 4.4 0.00081 19.4 0.1 4.3 2 2 0 3 3 3 3 Tetratricopeptide repeat MIT PF04212.13 ETO00459.1 - 1.4e-08 34.4 9.3 0.0013 18.5 0.1 3.9 3 1 1 4 4 4 3 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 ETO00459.1 - 2.4e-07 30.7 4.4 0.0047 17.0 0.7 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 ETO00459.1 - 1.3e-06 28.0 13.9 0.0036 17.0 0.8 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO00459.1 - 5.9e-06 26.3 0.3 7.5 7.2 0.0 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO00459.1 - 8.1e-06 26.0 0.0 2.4 9.0 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO00459.1 - 2.6e-05 24.7 0.0 0.19 12.4 0.0 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO00459.1 - 3.6e-05 24.0 0.0 0.69 10.2 0.1 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat Pep3_Vps18 PF05131.9 ETO00459.1 - 0.003 17.0 0.3 12 5.3 0.0 3.2 3 0 0 3 3 3 0 Pep3/Vps18/deep orange family Fis1_TPR_C PF14853.1 ETO00459.1 - 0.016 15.0 5.9 6 6.8 0.1 3.7 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat PPR PF01535.15 ETO00459.1 - 0.073 13.0 2.9 17 5.6 0.0 3.6 4 0 0 4 4 4 0 PPR repeat P22_AR_C PF10548.4 ETO00459.1 - 0.64 9.9 2.9 34 4.4 0.0 3.2 4 0 0 4 4 3 0 P22AR C-terminal domain DUF587 PF04532.7 ETO00460.1 - 0.015 14.2 0.1 0.47 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF587) RPA_C PF08784.6 ETO00461.1 - 0.0091 16.4 0.3 0.015 15.6 0.2 1.4 1 0 0 1 1 1 1 Replication protein A C terminal DUF2522 PF10747.4 ETO00462.1 - 0.067 13.2 1.5 0.11 12.4 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2522) DUF1523 PF07509.6 ETO00462.1 - 0.095 11.9 2.3 0.33 10.1 0.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1523) DUF2196 PF09962.4 ETO00462.1 - 0.17 11.7 0.8 0.46 10.2 0.1 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2196) DUF3655 PF12379.3 ETO00462.1 - 0.4 10.6 2.4 2.5 8.0 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3655) DUF775 PF05603.7 ETO00462.1 - 2.2 7.7 6.1 1.4 8.3 3.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF775) DUF4615 PF15393.1 ETO00462.1 - 4.8 7.4 8.2 14 5.9 0.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4615) Borrelia_P83 PF05262.6 ETO00463.1 - 0.17 10.1 15.6 0.19 9.9 10.8 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein POX PF07526.6 ETO00463.1 - 2 8.6 12.3 1.1 9.5 6.8 1.7 1 1 1 2 2 2 0 Associated with HOX Zip PF02535.17 ETO00463.1 - 3.9 6.3 9.0 4.7 6.1 6.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1510 PF07423.6 ETO00463.1 - 5.6 6.2 17.9 7 5.9 12.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) MIP-T3 PF10243.4 ETO00463.1 - 7.8 4.8 23.0 9.1 4.6 15.9 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2201_N PF13203.1 ETO00464.1 - 1.1 8.3 5.6 2 7.4 3.9 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain TPR_12 PF13424.1 ETO00467.1 - 1.1e-45 153.4 5.5 3e-18 65.5 0.1 3.3 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO00467.1 - 3.5e-28 97.0 29.4 3.1e-10 39.5 1.1 3.4 1 1 3 4 4 4 4 TPR repeat TPR_1 PF00515.23 ETO00467.1 - 3.8e-25 86.3 18.8 1.9e-08 33.5 0.4 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO00467.1 - 5.9e-24 83.2 0.0 6.7e-07 29.0 0.0 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO00467.1 - 8.1e-23 78.3 1.9 8.3e-07 28.3 0.0 4.7 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO00467.1 - 1.6e-19 68.1 22.6 2.3e-07 30.0 1.0 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO00467.1 - 3.9e-19 66.9 8.2 4.7e-07 29.2 0.2 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETO00467.1 - 1.1e-14 53.2 9.6 0.00083 19.3 0.0 4.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO00467.1 - 4.4e-09 36.7 0.0 0.017 15.7 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO00467.1 - 9.1e-08 32.1 3.3 0.021 14.9 1.3 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETO00467.1 - 4.8e-07 29.7 0.4 0.055 13.9 0.1 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO00467.1 - 6.2e-05 23.2 0.0 0.28 11.9 0.0 3.5 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO00467.1 - 0.00036 20.7 0.0 0.69 10.3 0.0 3.0 2 2 1 3 3 3 1 Tetratricopeptide repeat SNAP PF14938.1 ETO00467.1 - 0.02 14.0 2.9 0.87 8.6 1.1 2.5 1 1 1 2 2 2 0 Soluble NSF attachment protein, SNAP Sel1 PF08238.7 ETO00467.1 - 0.021 15.4 6.6 6.5 7.5 0.2 4.3 5 0 0 5 5 4 0 Sel1 repeat Pep3_Vps18 PF05131.9 ETO00467.1 - 0.042 13.2 0.2 10 5.5 0.0 2.9 2 1 0 2 2 2 0 Pep3/Vps18/deep orange family TPR_3 PF07720.7 ETO00467.1 - 0.074 12.8 17.9 0.3 10.9 0.1 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat MIT PF04212.13 ETO00467.1 - 0.2 11.5 7.0 0.99 9.3 0.5 3.3 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain RPN7 PF10602.4 ETO00467.1 - 0.21 10.9 2.3 20 4.4 0.1 3.1 3 1 1 4 4 4 0 26S proteasome subunit RPN7 PPR PF01535.15 ETO00467.1 - 2.2 8.4 13.4 7.4 6.7 0.0 4.9 5 0 0 5 5 5 0 PPR repeat DUF4363 PF14276.1 ETO00468.1 - 0.0012 18.4 1.1 0.0018 17.9 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4363) DUF2096 PF09869.4 ETO00468.1 - 0.012 15.5 0.9 0.013 15.4 0.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) TBCA PF02970.11 ETO00468.1 - 0.071 13.1 0.5 0.75 9.9 0.1 2.2 2 0 0 2 2 2 0 Tubulin binding cofactor A Sod_Fe_N PF00081.17 ETO00468.1 - 0.19 11.9 1.1 0.35 11.1 0.8 1.6 1 1 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain SR-25 PF10500.4 ETO00469.1 - 0.0023 17.4 4.8 0.0026 17.2 3.3 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Secretin_N_2 PF07655.8 ETO00469.1 - 0.47 10.8 16.4 0.13 12.6 2.3 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain zf-C3HC4_2 PF13923.1 ETO00470.1 - 0.0004 20.3 2.2 0.0016 18.4 1.5 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO00470.1 - 0.0044 16.8 4.5 0.0044 16.8 3.1 1.7 2 1 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 ETO00470.1 - 0.099 12.3 2.4 0.62 9.8 1.7 2.3 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING-like PF08746.6 ETO00470.1 - 1.5 8.9 10.1 5.3 7.1 7.0 1.9 1 1 1 2 2 2 0 RING-like domain zf-C3HC4 PF00097.20 ETO00470.1 - 8 6.2 11.7 0.77 9.4 3.8 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Spt5_N PF11942.3 ETO00471.1 - 0.0011 19.5 1.6 0.0014 19.2 1.1 1.1 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal DUF3837 PF12939.2 ETO00471.1 - 0.057 13.4 1.3 2 8.4 0.2 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF3837) PPP5 PF08321.7 ETO00471.1 - 0.085 12.8 0.3 0.3 11.1 0.1 1.8 1 1 1 2 2 2 0 PPP5 TPR repeat region DUF4113 PF13438.1 ETO00471.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4113) DUF3236 PF11576.3 ETO00472.1 - 0.01 15.2 0.1 0.028 13.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) EssA PF10661.4 ETO00473.1 - 0.072 12.7 1.2 0.088 12.4 0.8 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA NMT_C PF02799.10 ETO00475.1 - 0.58 9.5 3.5 0.29 10.5 0.4 1.7 2 0 0 2 2 2 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain SLAC1 PF03595.12 ETO00478.1 - 0.00041 19.1 1.7 0.00057 18.6 1.2 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel TraH PF06122.6 ETO00478.1 - 0.016 14.0 0.0 0.022 13.5 0.0 1.1 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein HAP1_N PF04849.8 ETO00479.1 - 0.0015 17.5 0.0 0.0019 17.2 0.0 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Radial_spoke PF04712.7 ETO00479.1 - 0.039 12.6 0.1 0.05 12.3 0.1 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein DUF3987 PF13148.1 ETO00479.1 - 0.71 8.3 4.5 0.95 7.9 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) GlcNAc PF11397.3 ETO00482.1 - 3.7e-32 111.7 0.2 5e-32 111.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) DUF2357 PF09823.4 ETO00484.1 - 0.0067 15.5 0.0 0.0081 15.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2357) DUF2360 PF10152.4 ETO00487.1 - 0.0099 16.1 1.3 0.012 15.9 0.9 1.1 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) PP_M1 PF03012.9 ETO00487.1 - 0.026 13.8 8.4 0.031 13.6 5.8 1.0 1 0 0 1 1 1 0 Phosphoprotein DUF3306 PF11748.3 ETO00487.1 - 0.13 12.9 5.2 0.18 12.4 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) PDCD2_C PF04194.8 ETO00487.1 - 0.18 11.3 5.8 0.24 10.9 4.0 1.2 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain DDRGK PF09756.4 ETO00487.1 - 0.61 9.4 12.2 0.76 9.1 8.5 1.1 1 0 0 1 1 1 0 DDRGK domain Peptidase_A3 PF02160.10 ETO00487.1 - 1.3 8.6 11.0 0.18 11.3 4.9 1.5 2 0 0 2 2 2 0 Cauliflower mosaic virus peptidase (A3) Atrophin-1 PF03154.10 ETO00487.1 - 1.7 6.6 7.8 2.2 6.3 5.4 1.0 1 0 0 1 1 1 0 Atrophin-1 family TPR_11 PF13414.1 ETO00488.1 - 1.2e-23 82.4 2.4 6.5e-15 54.5 0.1 2.2 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 ETO00488.1 - 4.1e-10 38.7 0.7 0.00072 19.2 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO00488.1 - 6.2e-09 35.0 7.2 1.8e-05 24.1 0.0 3.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO00488.1 - 4.5e-07 29.5 0.3 0.026 14.7 0.0 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO00488.1 - 0.001 18.6 0.7 0.062 13.1 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO00488.1 - 0.0011 19.3 0.0 2.1 9.2 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO00488.1 - 0.0019 18.0 0.2 1 9.2 0.0 3.2 3 1 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat DUF3808 PF10300.4 ETO00488.1 - 0.015 13.9 0.0 0.017 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) TPR_16 PF13432.1 ETO00488.1 - 0.023 15.3 0.0 0.98 10.1 0.0 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETO00488.1 - 0.043 14.1 0.1 19 5.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Pox_E2-like PF04497.7 ETO00489.1 - 0.055 11.4 1.2 0.053 11.5 0.8 1.0 1 0 0 1 1 1 0 Poxviridae protein Glutaredoxin PF00462.19 ETO00489.1 - 0.094 12.7 1.1 0.13 12.2 0.6 1.5 1 1 0 1 1 1 0 Glutaredoxin zf-CW PF07496.10 ETO00491.1 - 0.22 11.2 2.4 0.75 9.5 0.2 2.4 2 0 0 2 2 2 0 CW-type Zinc Finger Actin PF00022.14 ETO00492.1 - 1.2e-34 119.4 0.0 1.3e-34 119.3 0.0 1.0 1 0 0 1 1 1 1 Actin RNA_pol_Rpb1_1 PF04997.7 ETO00494.1 - 0.035 13.3 3.7 0.046 12.9 2.6 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 SKI PF01202.17 ETO00494.1 - 0.066 13.0 0.4 0.12 12.1 0.1 1.5 1 1 1 2 2 2 0 Shikimate kinase Ovate PF04844.8 ETO00494.1 - 0.09 12.5 0.2 0.56 10.0 0.1 2.1 2 0 0 2 2 2 0 Transcriptional repressor, ovate zf-C3HC4_3 PF13920.1 ETO00494.1 - 0.32 10.6 3.0 0.58 9.8 2.1 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H PF13771.1 ETO00495.1 - 0.00018 21.5 4.3 0.00033 20.7 3.0 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 ETO00495.1 - 0.00022 21.2 1.7 0.00034 20.5 1.2 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain PHD PF00628.24 ETO00495.1 - 0.13 12.0 8.8 0.37 10.5 6.1 1.8 1 1 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 ETO00495.1 - 0.55 10.2 9.1 0.13 12.2 3.3 2.0 2 0 0 2 2 2 0 RING-like domain ISG65-75 PF11727.3 ETO00498.1 - 0.031 13.3 7.8 0.05 12.6 5.4 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein FlaC_arch PF05377.6 ETO00498.1 - 0.38 10.6 6.3 0.14 12.0 1.3 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF3508 PF12018.3 ETO00498.1 - 0.58 9.0 6.9 1.2 8.0 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3508) DUF1664 PF07889.7 ETO00498.1 - 1.3 8.8 6.5 3.4 7.4 4.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) IncA PF04156.9 ETO00498.1 - 2.2 7.8 10.3 2.2 7.8 2.0 2.2 1 1 1 2 2 2 0 IncA protein FlxA PF14282.1 ETO00498.1 - 4.7 7.2 12.0 12 5.9 8.1 1.8 1 1 0 1 1 1 0 FlxA-like protein DUF4369 PF14289.1 ETO00499.1 - 0.1 12.6 0.4 0.11 12.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4369) Vpu PF00558.14 ETO00500.1 - 0.088 12.3 0.8 0.18 11.3 0.3 1.7 1 1 0 1 1 1 0 Vpu protein UCH PF00443.24 ETO00500.1 - 3.1 6.8 6.9 3.2 6.7 4.8 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Adaptin_binding PF10199.4 ETO00500.1 - 4 7.7 9.4 6.3 7.0 6.5 1.5 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Gag_spuma PF03276.9 ETO00501.1 - 0.31 9.3 10.3 0.33 9.2 7.2 1.1 1 0 0 1 1 1 0 Spumavirus gag protein FNIP_N PF14636.1 ETO00501.1 - 0.52 10.7 8.8 0.074 13.5 3.6 1.6 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus Arena_glycoprot PF00798.13 ETO00501.1 - 0.7 8.2 7.4 0.84 7.9 5.1 1.0 1 0 0 1 1 1 0 Arenavirus glycoprotein DUF3675 PF12428.3 ETO00501.1 - 1 9.6 3.3 1.1 9.5 0.6 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3675) PA26 PF04636.8 ETO00501.1 - 2.7 6.5 10.8 2.9 6.5 7.5 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RNA_pol_Rpb1_5 PF04998.12 ETO00501.1 - 3.6 6.7 10.8 4.3 6.5 7.5 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 SID-1_RNA_chan PF13965.1 ETO00501.1 - 5.5 5.0 10.2 6.5 4.7 7.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.11 ETO00501.1 - 7.3 6.4 8.9 9.7 5.9 6.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FUN14 PF04930.10 ETO00501.1 - 8 6.8 7.0 1.5e+02 2.7 4.9 2.1 1 1 0 1 1 1 0 FUN14 family TCTP PF00838.12 ETO00502.1 - 0.014 15.3 2.0 0.016 15.2 0.5 1.6 1 1 1 2 2 2 0 Translationally controlled tumour protein DUF2321 PF10083.4 ETO00502.1 - 0.093 12.2 0.4 0.12 11.8 0.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) TMA7 PF09072.5 ETO00502.1 - 0.14 12.6 2.0 0.27 11.7 1.4 1.5 1 0 0 1 1 1 0 Translation machinery associated TMA7 NACHT PF05729.7 ETO00503.1 - 0.0051 16.4 0.0 0.0053 16.4 0.0 1.1 1 0 0 1 1 1 1 NACHT domain DUF1359 PF07097.6 ETO00503.1 - 0.027 14.5 0.7 0.03 14.3 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1359) OmpH PF03938.9 ETO00504.1 - 0.00042 20.2 0.0 0.00074 19.4 0.0 1.3 1 1 0 1 1 1 1 Outer membrane protein (OmpH-like) DUF4252 PF14060.1 ETO00504.1 - 0.33 10.5 5.3 0.83 9.1 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4252) POX PF07526.6 ETO00504.1 - 7.1 6.8 9.1 2.8 8.1 4.5 1.6 2 0 0 2 2 2 0 Associated with HOX RNase_H2_suC PF08615.6 ETO00504.1 - 7.6 6.3 8.2 12 5.7 5.7 1.5 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) WD40 PF00400.27 ETO00505.1 - 1.4e-146 471.7 50.0 3.5e-13 48.8 0.2 15.3 15 0 0 15 15 15 14 WD domain, G-beta repeat DUF1258 PF06869.7 ETO00505.1 - 1.2e-07 31.1 5.1 0.022 13.8 0.1 5.3 3 2 5 8 8 8 2 Protein of unknown function (DUF1258) eIF2A PF08662.6 ETO00505.1 - 7.6e-07 29.0 7.1 0.99 9.0 0.1 6.1 2 2 3 6 6 6 2 Eukaryotic translation initiation factor eIF2A Pentapeptide PF00805.17 ETO00505.1 - 8.4e-06 24.9 0.2 1.7e-05 23.9 0.2 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO00505.1 - 1.9e-05 24.3 0.3 8.4e-05 22.3 0.2 2.2 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Mid2 PF04478.7 ETO00505.1 - 0.00042 19.7 18.1 2.5 7.4 0.1 7.5 5 1 4 9 9 9 3 Mid2 like cell wall stress sensor Pentapeptide_3 PF13576.1 ETO00505.1 - 0.00046 20.0 1.0 0.0017 18.1 0.7 2.0 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) NYD-SP28_assoc PF14775.1 ETO00505.1 - 0.00068 19.2 5.0 55 3.5 0.0 8.6 11 0 0 11 11 11 0 Sperm tail C-terminal domain Peptidase_C69 PF03577.10 ETO00505.1 - 0.0024 16.8 5.9 4.2 6.1 0.0 5.3 6 0 0 6 6 6 2 Peptidase family C69 PLD_C PF12357.3 ETO00505.1 - 0.0039 16.6 1.9 1.2e+02 2.2 0.0 7.0 9 1 2 11 11 11 0 Phospholipase D C terminal PD40 PF07676.7 ETO00505.1 - 0.0056 16.3 18.7 24 4.7 0.1 8.8 10 0 0 10 10 10 0 WD40-like Beta Propeller Repeat Hist_deacetyl PF00850.14 ETO00506.1 - 3.1e-09 36.5 0.0 6.8e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Histone deacetylase domain DUF3816 PF12822.2 ETO00506.1 - 0.078 12.8 0.1 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) ubiquitin PF00240.18 ETO00507.1 - 1.9e-33 113.6 0.5 3.5e-33 112.8 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 ETO00507.1 - 1.4e-17 63.1 0.4 1.4e-17 63.1 0.3 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 ETO00507.1 - 2.9e-06 27.4 0.2 1.5e-05 25.1 0.1 2.1 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 ETO00507.1 - 0.005 16.7 0.1 0.011 15.5 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TUG-UBL1 PF11470.3 ETO00507.1 - 0.036 13.9 0.6 0.076 12.9 0.0 1.8 2 0 0 2 2 2 0 GLUT4 regulating protein TUG DUF2407 PF10302.4 ETO00507.1 - 0.055 13.6 0.1 0.074 13.2 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain zf-RanBP PF00641.13 ETO00508.1 - 1.4e-06 27.2 0.9 1.4e-06 27.2 0.6 2.5 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others DZR PF12773.2 ETO00508.1 - 0.55 10.0 6.8 1.9 8.3 4.7 1.9 1 0 0 1 1 1 0 Double zinc ribbon C1_3 PF07649.7 ETO00508.1 - 4.4 7.4 6.1 0.47 10.5 0.5 2.0 2 0 0 2 2 2 0 C1-like domain Spindle_Spc25 PF08234.7 ETO00509.1 - 0.048 13.6 1.3 0.19 11.7 0.2 2.4 2 0 0 2 2 2 0 Chromosome segregation protein Spc25 SMC_N PF02463.14 ETO00509.1 - 0.092 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Tim54 PF11711.3 ETO00510.1 - 0.0016 17.1 0.4 0.0018 16.9 0.2 1.3 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Nop14 PF04147.7 ETO00510.1 - 0.0018 16.2 6.5 0.0018 16.2 4.5 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.7 ETO00510.1 - 0.0048 16.2 6.6 0.0052 16.1 4.6 1.1 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.9 ETO00510.1 - 0.0073 14.3 7.4 0.0085 14.1 5.1 1.1 1 0 0 1 1 1 1 CDC45-like protein Daxx PF03344.10 ETO00510.1 - 0.0092 14.5 8.5 0.01 14.3 5.9 1.1 1 0 0 1 1 1 1 Daxx Family YqfQ PF14181.1 ETO00510.1 - 0.029 14.4 3.5 0.039 13.9 2.4 1.2 1 0 0 1 1 1 0 YqfQ-like protein Sporozoite_P67 PF05642.6 ETO00510.1 - 0.056 11.3 2.1 0.065 11.0 1.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2457 PF10446.4 ETO00510.1 - 0.081 11.6 13.9 0.091 11.4 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) VID27 PF08553.5 ETO00510.1 - 0.83 7.8 16.2 1 7.5 11.3 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein RRN3 PF05327.6 ETO00510.1 - 2 6.4 6.3 2.4 6.1 4.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pox_Ag35 PF03286.9 ETO00510.1 - 2.5 7.5 12.1 3.5 7.1 8.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein HSP90 PF00183.13 ETO00510.1 - 6.8 4.9 12.0 9 4.5 8.3 1.1 1 0 0 1 1 1 0 Hsp90 protein DLIC PF05783.6 ETO00512.1 - 0.034 12.8 0.5 0.048 12.3 0.4 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Helicase_C_2 PF13307.1 ETO00512.1 - 0.052 13.5 0.5 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Helicase C-terminal domain RPA_interact_M PF14767.1 ETO00512.1 - 0.11 13.2 0.8 0.39 11.4 0.1 2.0 2 0 0 2 2 2 0 Replication protein A interacting middle Pneumo_M2 PF07380.6 ETO00512.1 - 0.14 12.1 4.2 0.18 11.8 1.4 2.1 2 1 1 3 3 3 0 Pneumovirus M2 protein NIR_SIR PF01077.17 ETO00513.1 - 0.09 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain PBP1_TM PF14812.1 ETO00513.1 - 0.16 12.2 0.7 0.33 11.3 0.5 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SID-1_RNA_chan PF13965.1 ETO00514.1 - 0.015 13.4 0.8 0.018 13.2 0.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4153 PF13687.1 ETO00514.1 - 0.063 12.7 0.4 0.084 12.3 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4153) LRRC37AB_C PF14914.1 ETO00514.1 - 0.58 9.5 3.9 0.67 9.3 1.0 2.0 1 1 1 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain WD40 PF00400.27 ETO00515.1 - 2.2e-25 87.5 4.8 3e-10 39.5 0.2 3.6 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO00515.1 - 1.9e-05 22.9 3.5 0.34 8.9 0.0 3.6 3 1 1 4 4 4 3 Nucleoporin Nup120/160 MMR_HSR1 PF01926.18 ETO00516.1 - 8.4e-08 32.1 0.2 1.4e-07 31.4 0.2 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 ETO00516.1 - 0.0022 17.2 0.1 0.0036 16.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 ETO00516.1 - 0.0047 17.4 0.2 0.0087 16.5 0.1 1.6 1 1 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 ETO00516.1 - 0.0079 15.3 0.1 0.014 14.4 0.0 1.5 2 0 0 2 2 2 1 AIG1 family NAD_binding_7 PF13241.1 ETO00516.1 - 0.02 15.1 0.0 0.038 14.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ABC_tran PF00005.22 ETO00516.1 - 0.035 14.4 0.1 0.089 13.0 0.2 1.7 2 1 0 2 2 1 0 ABC transporter AAA_18 PF13238.1 ETO00516.1 - 0.042 14.1 0.1 0.059 13.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain SecY PF00344.15 ETO00516.1 - 0.058 12.3 0.0 0.065 12.1 0.0 1.1 1 0 0 1 1 1 0 SecY translocase DUF815 PF05673.8 ETO00516.1 - 0.068 12.0 0.1 0.12 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.1 ETO00516.1 - 0.075 12.5 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.12 ETO00516.1 - 0.15 11.8 0.9 0.2 11.4 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_5 PF07728.9 ETO00516.1 - 0.19 11.4 0.3 1.3 8.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF4283 PF14111.1 ETO00517.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4283) Ran-binding PF05508.6 ETO00518.1 - 0.0039 16.1 1.9 0.0045 15.9 0.7 1.5 1 1 0 1 1 1 1 RanGTP-binding protein DUF4363 PF14276.1 ETO00518.1 - 0.045 13.4 0.4 0.045 13.4 0.3 1.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4363) HrpF PF06266.7 ETO00518.1 - 0.11 12.7 0.3 0.78 9.9 0.1 2.5 2 1 0 2 2 2 0 HrpF protein NUC130_3NT PF08158.7 ETO00518.1 - 0.11 12.7 0.6 0.36 11.1 0.1 2.2 2 1 0 2 2 2 0 NUC130/3NT domain NAAA-beta PF15508.1 ETO00518.1 - 0.12 12.7 0.3 1.3 9.4 0.0 2.3 1 1 1 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase WD40 PF00400.27 ETO00519.1 - 1.6e-46 154.5 4.6 9.9e-14 50.6 0.0 4.0 4 0 0 4 4 4 4 WD domain, G-beta repeat eIF2A PF08662.6 ETO00519.1 - 4.8e-08 32.9 0.0 0.0004 20.1 0.0 1.9 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.4 ETO00519.1 - 4.2e-06 25.9 2.8 2.5 7.4 0.0 4.7 4 0 0 4 4 4 2 Proteasome subunit A N-terminal signature Nup160 PF11715.3 ETO00519.1 - 0.00018 19.7 0.0 0.12 10.4 0.0 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO00519.1 - 0.00042 19.7 0.1 0.11 11.7 0.0 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4221) PQQ_2 PF13360.1 ETO00519.1 - 0.00048 19.6 0.1 0.84 9.0 0.0 2.1 1 1 1 2 2 2 2 PQQ-like domain PLD_C PF12357.3 ETO00519.1 - 0.00065 19.1 0.1 0.17 11.4 0.0 3.0 1 1 2 3 3 3 1 Phospholipase D C terminal Cytochrom_D1 PF02239.11 ETO00519.1 - 0.0013 17.0 0.9 0.69 8.1 0.1 2.2 1 1 0 2 2 2 2 Cytochrome D1 heme domain B_lectin PF01453.19 ETO00519.1 - 0.0015 18.4 0.1 0.0055 16.5 0.0 1.8 1 1 1 2 2 2 1 D-mannose binding lectin Nucleoporin_N PF08801.6 ETO00519.1 - 0.0035 16.1 2.3 1.4 7.6 0.0 2.9 1 1 2 3 3 3 1 Nup133 N terminal like Cuticle_1 PF08140.6 ETO00519.1 - 0.012 15.4 0.4 10 6.0 0.0 3.9 4 1 1 5 5 5 0 Crustacean cuticle protein repeat Gmad1 PF10647.4 ETO00519.1 - 0.016 14.5 0.0 0.064 12.6 0.0 2.0 1 1 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain DUF1258 PF06869.7 ETO00519.1 - 0.031 13.3 0.0 1.7 7.6 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1258) PD40 PF07676.7 ETO00519.1 - 0.034 13.8 2.0 6.5 6.5 0.0 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Reg_prop PF07494.6 ETO00519.1 - 0.035 14.1 0.1 18 5.8 0.0 3.5 3 0 0 3 3 3 0 Two component regulator propeller NYD-SP28_assoc PF14775.1 ETO00519.1 - 0.065 12.9 0.1 45 3.8 0.0 3.1 3 0 0 3 3 3 0 Sperm tail C-terminal domain DPPIV_N PF00930.16 ETO00519.1 - 0.08 11.5 0.1 12 4.3 0.0 3.0 1 1 2 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nbas_N PF15492.1 ETO00519.1 - 0.089 11.8 0.4 0.62 9.1 0.1 2.0 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal PQQ_3 PF13570.1 ETO00519.1 - 0.092 13.0 0.1 7.5 6.9 0.0 3.0 2 1 1 3 3 3 0 PQQ-like domain TonB_2 PF13103.1 ETO00519.1 - 0.15 12.1 1.2 2.1 8.4 0.0 2.7 2 1 1 3 3 3 0 TonB C terminal Ank_2 PF12796.2 ETO00521.1 - 2.5e-08 34.1 0.4 1.1e-07 32.0 0.1 2.1 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO00521.1 - 9.8e-08 31.4 0.2 1.7e-06 27.5 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 ETO00521.1 - 9.3e-07 28.5 0.5 0.00046 20.1 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 ETO00521.1 - 2.5e-06 27.5 1.8 5.4e-06 26.4 0.2 2.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO00521.1 - 1.3e-05 25.5 0.5 0.00072 20.0 0.2 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Saccharop_dh PF03435.13 ETO00521.1 - 0.11 11.4 0.1 1.1 8.0 0.0 1.9 1 1 0 2 2 2 0 Saccharopine dehydrogenase WES_acyltransf PF03007.11 ETO00522.1 - 9.6e-07 28.6 0.0 0.022 14.3 0.0 2.7 2 1 0 2 2 2 2 Wax ester synthase-like Acyl-CoA acyltransferase domain Secretin_N_2 PF07655.8 ETO00522.1 - 0.029 14.7 3.9 0.029 14.7 2.7 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain Pex14_N PF04695.8 ETO00522.1 - 0.056 13.4 1.0 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF912 PF06024.7 ETO00522.1 - 6.9 6.7 7.7 4.6 7.3 2.7 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PAP2_C PF14360.1 ETO00524.1 - 1.9e-16 60.0 11.7 1.9e-16 60.0 8.1 2.0 2 0 0 2 2 2 1 PAP2 superfamily C-terminal PAP2 PF01569.16 ETO00524.1 - 3.3e-07 30.0 4.2 3.3e-07 30.0 2.9 1.7 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 ETO00524.1 - 0.00094 18.7 4.2 0.0013 18.2 2.9 1.2 1 0 0 1 1 1 1 PAP2 superfamily Kinesin PF00225.18 ETO00525.1 - 0.01 14.5 0.0 0.012 14.2 0.0 1.1 1 0 0 1 1 1 0 Kinesin motor domain PTB PF08416.8 ETO00525.1 - 0.11 12.3 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotyrosine-binding domain Ank_5 PF13857.1 ETO00526.1 - 2.1e-07 30.9 0.2 5e-07 29.7 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO00526.1 - 1.4e-06 28.0 0.7 1.1e-05 25.2 0.0 2.5 2 1 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 ETO00526.1 - 4.9e-06 26.8 0.6 1e-05 25.8 0.4 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO00526.1 - 8.7e-06 25.9 0.2 1.1e-05 25.6 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO00526.1 - 0.00016 21.2 0.0 0.00066 19.3 0.0 2.0 2 1 0 2 2 2 1 Ankyrin repeat TetR_C_8 PF14278.1 ETO00526.1 - 0.84 10.0 5.2 0.25 11.7 1.5 1.8 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region Nop53 PF07767.6 ETO00527.1 - 2.3 7.1 56.8 3 6.7 39.3 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CENP-T PF15511.1 ETO00527.1 - 2.6 7.1 40.6 3.9 6.5 28.1 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Daxx PF03344.10 ETO00527.1 - 5.9 5.2 65.8 9.6 4.5 45.6 1.4 1 0 0 1 1 1 0 Daxx Family Polysacc_deac_1 PF01522.16 ETO00528.1 - 0.083 12.5 1.8 0.13 11.8 1.1 1.6 1 1 0 1 1 1 0 Polysaccharide deacetylase DUF3441 PF11923.3 ETO00528.1 - 0.75 9.3 3.2 11 5.6 2.2 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3441) DUF724 PF05266.9 ETO00528.1 - 6.1 6.4 24.0 0.48 10.0 10.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF4615 PF15393.1 ETO00531.1 - 0.067 13.4 0.3 0.12 12.5 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4615) Tox-PLDMTX PF15645.1 ETO00531.1 - 0.93 9.5 6.5 0.75 9.8 3.6 1.6 1 1 0 1 1 1 0 Dermonecrotoxin of the Papain-like fold GlutR_dimer PF00745.15 ETO00532.1 - 0.08 12.9 5.2 0.058 13.3 0.3 3.0 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF258 PF03193.11 ETO00533.1 - 3.5e-06 26.2 0.3 3.1e-05 23.2 0.2 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 ETO00533.1 - 2.8e-05 24.0 0.5 9.7e-05 22.3 0.1 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.22 ETO00533.1 - 0.00022 21.5 0.0 0.00034 20.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Dynamin_N PF00350.18 ETO00533.1 - 0.00031 20.5 2.0 0.45 10.3 0.0 2.5 2 1 0 3 3 3 2 Dynamin family Miro PF08477.8 ETO00533.1 - 0.0016 18.8 0.3 0.0036 17.7 0.1 1.7 1 1 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 ETO00533.1 - 0.0029 17.5 0.5 0.0051 16.7 0.2 1.8 2 1 0 2 2 1 1 AAA domain T2SE PF00437.15 ETO00533.1 - 0.0034 16.3 0.0 0.0045 15.9 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 ETO00533.1 - 0.0041 16.6 0.0 0.0073 15.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain G-alpha PF00503.15 ETO00533.1 - 0.014 14.0 0.1 0.019 13.6 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit AAA_22 PF13401.1 ETO00533.1 - 0.021 14.9 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 ETO00533.1 - 0.037 13.2 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein SRP54 PF00448.17 ETO00533.1 - 0.037 13.4 0.1 0.078 12.4 0.1 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_25 PF13481.1 ETO00533.1 - 0.04 13.3 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 ETO00533.1 - 0.043 12.7 0.0 0.063 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.1 ETO00533.1 - 0.053 13.5 0.0 0.069 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain MCM PF00493.18 ETO00533.1 - 0.061 12.1 0.0 0.086 11.6 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family CoA_trans PF01144.18 ETO00533.1 - 0.066 12.3 0.0 0.094 11.8 0.0 1.3 1 0 0 1 1 1 0 Coenzyme A transferase RNA_helicase PF00910.17 ETO00533.1 - 0.067 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Septin PF00735.13 ETO00533.1 - 0.074 12.0 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_PrkA PF08298.6 ETO00533.1 - 0.083 11.5 0.0 0.093 11.3 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain AAA_19 PF13245.1 ETO00533.1 - 0.095 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain TrwB_AAD_bind PF10412.4 ETO00533.1 - 0.099 11.2 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain PEPCK_ATP PF01293.15 ETO00533.1 - 0.11 10.9 0.0 0.15 10.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_11 PF13086.1 ETO00533.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 ETO00533.1 - 0.12 11.8 0.2 0.33 10.4 0.1 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 ETO00533.1 - 0.27 11.5 0.2 0.27 11.5 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_23 PF13476.1 ETO00533.1 - 3.6 7.8 8.7 0.6 10.3 2.5 1.9 1 1 1 2 2 2 0 AAA domain GDA1_CD39 PF01150.12 ETO00534.1 - 0.0015 17.0 1.3 0.0019 16.8 0.9 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family GDA1_CD39 PF01150.12 ETO00535.1 - 9.4e-44 149.5 0.0 1.2e-43 149.2 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family KOW PF00467.24 ETO00535.1 - 0.0025 17.4 0.0 0.0058 16.3 0.0 1.6 1 0 0 1 1 1 1 KOW motif SH3_3 PF08239.6 ETO00535.1 - 0.33 11.1 2.0 0.58 10.3 0.9 1.8 1 1 1 2 2 2 0 Bacterial SH3 domain DUF739 PF05339.6 ETO00537.1 - 0.034 13.9 0.3 0.055 13.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF739) DUF1566 PF07603.6 ETO00537.1 - 0.064 12.9 0.4 0.092 12.4 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1566) Staphostatin_A PF09022.5 ETO00537.1 - 0.12 12.2 3.0 0.056 13.2 0.4 1.6 2 0 0 2 2 2 0 Staphostatin A Secretin_N_2 PF07655.8 ETO00538.1 - 4 7.8 8.7 6.8 7.1 6.0 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Peptidase_S9_N PF02897.10 ETO00540.1 - 0.14 10.6 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain HCO3_cotransp PF00955.16 ETO00541.1 - 0.0058 15.3 0.2 0.0071 15.0 0.1 1.0 1 0 0 1 1 1 1 HCO3- transporter family Secretin_N_2 PF07655.8 ETO00541.1 - 0.6 10.5 13.5 0.88 9.9 9.4 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain DUF788 PF05620.6 ETO00541.1 - 1.2 9.0 5.1 0.23 11.3 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF788) Methyltransf_12 PF08242.7 ETO00541.1 - 1.3 9.5 4.2 2.9 8.4 2.9 1.7 1 1 0 1 1 1 0 Methyltransferase domain Pex14_N PF04695.8 ETO00541.1 - 2 8.4 5.6 3 7.8 3.9 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3357 PF11837.3 ETO00541.1 - 2 8.3 5.8 32 4.4 3.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) GRP PF07172.6 ETO00542.1 - 0.97 9.9 16.8 1.5 9.3 11.6 1.3 1 0 0 1 1 1 0 Glycine rich protein family TP53IP5 PF15331.1 ETO00543.1 - 0.063 13.1 0.1 0.077 12.8 0.1 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Kelch_2 PF07646.10 ETO00544.1 - 0.0071 16.0 0.1 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 Kelch motif SecA_DEAD PF07517.9 ETO00545.1 - 0.017 14.4 0.0 0.089 12.0 0.0 2.4 2 2 0 2 2 2 0 SecA DEAD-like domain Rep_4 PF05797.6 ETO00547.1 - 0.0086 14.8 3.7 0.0086 14.8 2.6 1.1 1 0 0 1 1 1 1 Yeast trans-acting factor (REP1/REP2) COG2 PF06148.6 ETO00547.1 - 0.013 15.4 2.2 0.013 15.4 1.5 1.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin_2 PF14523.1 ETO00547.1 - 0.013 15.5 4.0 0.023 14.6 2.8 1.5 1 0 0 1 1 1 0 Syntaxin-like protein GatB_Yqey PF02637.13 ETO00547.1 - 0.014 15.1 5.1 0.017 14.8 3.5 1.2 1 0 0 1 1 1 0 GatB domain RmuC PF02646.11 ETO00547.1 - 0.049 12.4 4.6 0.06 12.1 3.2 1.2 1 0 0 1 1 1 0 RmuC family APG6 PF04111.7 ETO00547.1 - 0.11 11.5 7.7 0.12 11.3 5.4 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF948 PF06103.6 ETO00547.1 - 0.13 12.1 4.5 0.11 12.4 0.6 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) zf-HC5HC2H PF13771.1 ETO00547.1 - 0.2 11.8 1.2 0.29 11.3 0.8 1.4 1 1 0 1 1 1 0 PHD-like zinc-binding domain DUF3770 PF12603.3 ETO00547.1 - 0.22 10.6 7.5 0.24 10.4 5.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3770) LOH1CR12 PF10158.4 ETO00547.1 - 0.26 11.0 3.9 0.31 10.8 2.7 1.1 1 0 0 1 1 1 0 Tumour suppressor protein MIT PF04212.13 ETO00547.1 - 0.33 10.8 3.3 0.56 10.1 0.3 2.0 1 1 1 2 2 2 0 MIT (microtubule interacting and transport) domain FUN14 PF04930.10 ETO00547.1 - 0.39 11.0 2.9 0.83 9.9 2.0 1.6 1 1 0 1 1 1 0 FUN14 family Lge1 PF11488.3 ETO00547.1 - 0.45 10.7 4.4 0.12 12.5 0.8 1.7 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 Atg14 PF10186.4 ETO00547.1 - 2.9 6.7 9.8 3.2 6.6 6.8 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Rho_Binding PF08912.6 ETO00547.1 - 3 8.2 12.0 0.3 11.3 4.5 1.9 1 1 1 2 2 2 0 Rho Binding PseudoU_synth_2 PF00849.17 ETO00548.1 - 7.2e-06 25.9 0.8 1.2e-05 25.2 0.3 1.7 2 1 0 2 2 2 1 RNA pseudouridylate synthase Pox_RNA_Pol_19 PF05320.7 ETO00548.1 - 0.032 13.9 1.5 0.052 13.3 1.1 1.4 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF1292 PF06949.6 ETO00548.1 - 0.11 12.8 2.0 0.41 11.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1292) Gal-bind_lectin PF00337.17 ETO00549.1 - 0.064 12.5 0.2 2.4 7.5 0.1 2.4 1 1 0 2 2 2 0 Galactoside-binding lectin NifW PF03206.9 ETO00550.1 - 0.023 14.7 0.1 0.026 14.6 0.1 1.2 1 0 0 1 1 1 0 Nitrogen fixation protein NifW DUF2365 PF10157.4 ETO00550.1 - 0.076 12.9 0.0 0.079 12.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) PUB PF09409.5 ETO00550.1 - 0.3 10.8 2.7 1.2 8.9 1.9 1.8 1 1 0 1 1 1 0 PUB domain Med8 PF10232.4 ETO00551.1 - 0.026 14.0 1.5 0.041 13.3 1.0 1.3 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 GSH_synthase PF03199.10 ETO00551.1 - 0.07 13.2 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Eukaryotic glutathione synthase Nbs1_C PF08599.5 ETO00551.1 - 0.19 11.6 0.0 0.19 11.6 0.0 3.6 4 0 0 4 4 4 0 DNA damage repair protein Nbs1 Perilipin PF03036.11 ETO00551.1 - 0.24 10.2 1.4 0.29 9.9 1.0 1.2 1 0 0 1 1 1 0 Perilipin family Dsl1_C PF11989.3 ETO00552.1 - 0.013 14.6 1.0 0.014 14.5 0.7 1.1 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 C terminal Rep_Org_C PF06926.6 ETO00552.1 - 0.042 13.9 0.2 1.6 8.8 0.0 2.1 2 0 0 2 2 2 0 Putative replisome organiser protein C-terminus OLF PF02191.11 ETO00552.1 - 0.043 13.0 0.7 0.045 13.0 0.5 1.0 1 0 0 1 1 1 0 Olfactomedin-like domain SAM_decarbox PF01536.11 ETO00554.1 - 2.1e-34 118.6 0.0 6.7e-34 117.0 0.0 1.7 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase GOLD_2 PF13897.1 ETO00554.1 - 0.064 13.4 0.3 0.09 13.0 0.2 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Pex14_N PF04695.8 ETO00554.1 - 0.072 13.1 1.4 0.11 12.5 1.0 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Apc15p PF05841.6 ETO00554.1 - 0.33 11.7 11.6 0.47 11.2 8.1 1.2 1 0 0 1 1 1 0 Apc15p protein Folate_carrier PF01770.13 ETO00554.1 - 0.54 8.7 2.6 0.73 8.2 1.8 1.1 1 0 0 1 1 1 0 Reduced folate carrier DUF912 PF06024.7 ETO00554.1 - 0.61 10.1 10.9 0.9 9.6 7.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Menin PF05053.8 ETO00554.1 - 6.9 4.7 7.6 8.8 4.3 5.3 1.1 1 0 0 1 1 1 0 Menin Zip PF02535.17 ETO00555.1 - 0.053 12.5 2.5 0.084 11.8 1.8 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 ETO00555.1 - 0.23 10.8 14.9 0.028 13.7 7.1 1.8 2 0 0 2 2 2 0 Selenoprotein P, N terminal region DUF2457 PF10446.4 ETO00555.1 - 0.69 8.5 12.2 1.3 7.7 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RGS PF00615.14 ETO00556.1 - 2.4e-10 40.5 1.8 4.8e-10 39.5 1.2 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain EpsG PF14897.1 ETO00556.1 - 0.0082 15.1 3.1 0.015 14.2 2.2 1.3 1 0 0 1 1 1 1 EpsG family DUF3816 PF12822.2 ETO00556.1 - 0.12 12.2 2.5 0.21 11.4 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) DUF2347 PF09804.4 ETO00557.1 - 2.3 7.3 9.7 0.54 9.5 4.2 1.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2347) RRM_6 PF14259.1 ETO00558.1 - 5.2e-14 51.9 2.2 4.7e-07 29.6 0.1 2.7 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO00558.1 - 3.2e-12 46.0 1.2 7.5e-11 41.7 0.1 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO00558.1 - 1.3e-10 40.7 0.2 3.2e-06 26.6 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAP_GLY PF01302.20 ETO00560.1 - 4.7e-17 61.4 0.0 7.6e-17 60.7 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 ETO00560.1 - 1.1e-14 54.3 0.4 6.9e-14 51.8 0.1 2.2 2 0 0 2 2 2 1 Ubiquitin-like domain YqhG PF11079.3 ETO00560.1 - 0.03 13.1 0.1 0.036 12.8 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function 5_3_exonuc_N PF02739.11 ETO00560.1 - 0.066 12.5 0.3 0.11 11.8 0.2 1.3 1 1 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain ERM PF00769.14 ETO00561.1 - 0.00081 19.0 22.4 0.0012 18.4 15.5 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family HALZ PF02183.13 ETO00561.1 - 0.15 11.7 8.4 2.1 8.1 0.8 3.5 1 1 3 4 4 4 0 Homeobox associated leucine zipper DUF1875 PF08961.5 ETO00561.1 - 0.64 9.2 16.2 0.78 9.0 0.9 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1875) CCDC155 PF14662.1 ETO00561.1 - 0.91 9.0 19.7 1.5 8.3 13.7 1.4 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 Atg14 PF10186.4 ETO00561.1 - 5.6 5.8 20.2 7.5 5.3 14.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Med5 PF08689.5 ETO00561.1 - 6.7 4.2 11.5 8.3 3.9 8.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit Med5 UPF0449 PF15136.1 ETO00561.1 - 9.3 6.5 13.4 1.1 9.5 4.2 2.3 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 NACHT PF05729.7 ETO00564.1 - 1.7e-06 27.8 0.0 1.8e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 NACHT domain PAN_3 PF08277.7 ETO00564.1 - 0.021 14.4 2.0 0.025 14.1 0.4 1.9 2 0 0 2 2 2 0 PAN-like domain Hydrolase PF00702.21 ETO00567.1 - 2.4e-09 37.9 0.0 2.6e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETO00567.1 - 3.1e-05 24.2 0.0 3.2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 ETO00567.1 - 0.0026 17.6 0.0 0.0037 17.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Radical_SAM PF04055.16 ETO00567.1 - 0.038 14.1 0.0 0.044 13.9 0.0 1.1 1 0 0 1 1 1 0 Radical SAM superfamily SIS PF01380.17 ETO00567.1 - 0.093 12.3 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 SIS domain Methyltransf_8 PF05148.10 ETO00567.1 - 0.12 12.0 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Hypothetical methyltransferase RRM_1 PF00076.17 ETO00569.1 - 5e-18 64.5 0.9 2.8e-07 30.0 0.3 3.9 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO00569.1 - 2.1e-17 62.8 0.4 2.9e-09 36.7 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO00569.1 - 1.9e-10 40.3 0.2 8.6e-05 22.3 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HEAT PF02985.17 ETO00570.1 - 8.9e-09 34.7 0.0 0.00046 20.0 0.0 2.6 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.1 ETO00570.1 - 2.2e-06 27.8 0.0 3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 HEAT repeats HEAT_PBS PF03130.11 ETO00570.1 - 0.012 16.0 0.0 8.9 7.1 0.0 2.7 2 1 0 2 2 2 0 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 ETO00570.1 - 0.012 16.0 0.0 0.066 13.7 0.0 2.0 1 1 1 2 2 2 0 HEAT-like repeat Colicin PF01024.14 ETO00570.1 - 0.059 12.9 0.5 0.078 12.5 0.4 1.2 1 0 0 1 1 1 0 Colicin pore forming domain DUF1102 PF06510.6 ETO00571.1 - 0.063 13.0 0.2 0.48 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1102) RVT_1 PF00078.22 ETO00572.1 - 4.7e-29 101.2 0.1 5e-29 101.1 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.27 ETO00575.1 - 7e-10 38.4 0.6 6.1e-09 35.4 0.0 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF603 PF04645.7 ETO00575.1 - 0.0039 17.1 0.7 0.005 16.7 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF603 DUF2721 PF11026.3 ETO00575.1 - 0.16 11.6 0.3 0.24 11.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF3186 PF11382.3 ETO00575.1 - 0.23 10.5 1.3 0.28 10.2 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) CENP-H PF05837.7 ETO00575.1 - 0.29 11.3 6.9 0.42 10.8 4.8 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF3941 PF13081.1 ETO00575.1 - 3.5 7.6 8.1 0.12 12.4 1.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3941) CMV_1a PF12467.3 ETO00577.1 - 0.69 10.2 7.8 0.94 9.8 1.7 2.7 2 1 0 2 2 2 0 Cucumber mosaic virus 1a protein family Tom7 PF08038.7 ETO00578.1 - 6.5e-05 22.3 0.1 0.00014 21.2 0.0 1.5 1 0 0 1 1 1 1 TOM7 family DUF3382 PF11862.3 ETO00579.1 - 0.079 12.8 0.2 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) EamA PF00892.15 ETO00579.1 - 6 6.9 13.5 0.1 12.6 4.3 1.8 2 0 0 2 2 2 0 EamA-like transporter family Metallophos_C PF14008.1 ETO00580.1 - 7.1e-15 54.8 0.1 1.4e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.23 ETO00580.1 - 1e-09 38.1 0.5 2.3e-09 36.9 0.4 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Geminin PF07412.7 ETO00581.1 - 0.0062 16.2 4.7 0.0062 16.2 3.3 2.9 2 1 1 3 3 3 1 Geminin TF_AP-2 PF03299.9 ETO00581.1 - 0.04 13.4 5.2 0.048 13.2 3.6 1.1 1 0 0 1 1 1 0 Transcription factor AP-2 TEX19 PF15553.1 ETO00581.1 - 0.042 13.7 1.1 0.051 13.4 0.7 1.2 1 0 0 1 1 1 0 Testis-expressed protein 19 She9_MDM33 PF05546.6 ETO00581.1 - 0.071 12.6 7.0 0.094 12.2 4.5 1.5 1 1 0 1 1 1 0 She9 / Mdm33 family GspL_C PF12693.2 ETO00581.1 - 0.13 12.0 0.1 0.13 12.0 0.1 1.6 2 0 0 2 2 2 0 GspL periplasmic domain DUF641 PF04859.7 ETO00581.1 - 0.34 10.6 16.1 1.1 9.0 4.2 2.4 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DivIVA PF05103.8 ETO00581.1 - 0.75 9.8 19.2 0.074 13.1 5.8 2.3 2 1 0 2 2 2 0 DivIVA protein DUF4584 PF15223.1 ETO00581.1 - 0.76 8.9 5.5 0.85 8.8 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4584) DUF724 PF05266.9 ETO00581.1 - 0.79 9.3 17.3 0.061 12.9 6.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) TPD52 PF04201.10 ETO00581.1 - 0.83 9.3 12.2 0.29 10.8 2.2 2.2 2 0 0 2 2 2 0 Tumour protein D52 family SID-1_RNA_chan PF13965.1 ETO00581.1 - 1.4 7.0 6.4 1.5 6.8 4.5 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CCDC155 PF14662.1 ETO00581.1 - 2.8 7.5 19.7 3.7 7.0 4.9 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 DUF4407 PF14362.1 ETO00581.1 - 5 5.9 8.6 7.4 5.4 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Vfa1 PF08432.5 ETO00581.1 - 7 6.6 18.6 1.1 9.2 9.4 1.9 1 1 1 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF4140 PF13600.1 ETO00581.1 - 7.4 7.0 10.1 8.6 6.8 2.6 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) FKBP_N PF01346.13 ETO00581.1 - 10 6.2 13.6 0.36 10.8 4.9 1.8 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Trypan_glycop_C PF10659.4 ETO00582.1 - 0.021 15.0 0.2 0.021 15.0 0.1 1.7 2 0 0 2 2 2 0 Trypanosome variant surface glycoprotein C-terminal domain RRN3 PF05327.6 ETO00582.1 - 0.024 12.7 3.7 0.037 12.1 2.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF3393 PF11873.3 ETO00582.1 - 0.057 12.9 0.6 0.075 12.5 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3393) B56 PF01603.15 ETO00583.1 - 3.4e-102 342.1 2.8 4.1e-102 341.8 1.9 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) RE_LlaMI PF09562.5 ETO00584.1 - 0.075 12.1 0.0 0.092 11.8 0.0 1.1 1 0 0 1 1 1 0 LlaMI restriction endonuclease SPOC PF07744.8 ETO00585.1 - 0.00062 20.2 0.0 0.0019 18.6 0.0 1.9 1 0 0 1 1 1 1 SPOC domain Peroxin-22 PF12827.2 ETO00585.1 - 0.0048 16.6 2.2 0.035 13.7 0.0 3.5 4 1 0 4 4 4 1 Peroxisomal biogenesis protein family AAA_22 PF13401.1 ETO00585.1 - 0.023 14.8 0.0 0.55 10.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 ETO00585.1 - 0.032 14.2 0.1 5.5 6.9 0.0 2.4 1 1 1 2 2 2 0 AAA ATPase domain AAA_5 PF07728.9 ETO00585.1 - 0.058 13.1 0.1 0.82 9.3 0.0 2.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 ETO00585.1 - 0.062 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) JAB PF01398.16 ETO00590.1 - 1.9e-17 63.0 0.0 4.3e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 ETO00590.1 - 5.3e-05 22.7 0.0 9.1e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MSP1_C PF07462.6 ETO00590.1 - 0.074 11.4 3.1 0.098 11.0 2.1 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus SOG2 PF10428.4 ETO00590.1 - 0.089 11.4 9.8 0.096 11.3 6.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein 14-3-3 PF00244.15 ETO00591.1 - 4.9e-53 179.6 7.2 1.5e-33 115.8 0.5 2.2 1 1 1 2 2 2 2 14-3-3 protein Exo_endo_phos_2 PF14529.1 ETO00592.1 - 6.5e-12 45.1 1.1 1.2e-11 44.2 0.5 1.5 1 1 1 2 2 2 1 Endonuclease-reverse transcriptase DS PF01916.12 ETO00594.1 - 0.03 13.4 0.0 0.03 13.4 0.0 1.0 1 0 0 1 1 1 0 Deoxyhypusine synthase Lebercilin PF15619.1 ETO00595.1 - 0.00015 21.2 13.1 0.00021 20.7 9.1 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Katanin_con80 PF13925.1 ETO00595.1 - 0.0074 16.0 2.7 0.011 15.4 1.9 1.3 1 0 0 1 1 1 1 con80 domain of Katanin LOH1CR12 PF10158.4 ETO00595.1 - 0.0077 16.0 2.2 0.01 15.6 1.5 1.2 1 0 0 1 1 1 1 Tumour suppressor protein AAA_13 PF13166.1 ETO00595.1 - 0.021 13.3 6.9 0.024 13.1 4.8 1.1 1 0 0 1 1 1 0 AAA domain Sec8_exocyst PF04048.9 ETO00595.1 - 0.023 14.3 4.1 0.034 13.7 2.8 1.3 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain MMS19_N PF14500.1 ETO00595.1 - 0.028 13.7 3.4 0.036 13.3 2.4 1.0 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II Sipho_Gp157 PF05565.6 ETO00595.1 - 0.034 13.7 7.1 0.05 13.1 4.9 1.2 1 0 0 1 1 1 0 Siphovirus Gp157 Rota_NSP3 PF01665.11 ETO00595.1 - 0.046 12.6 8.2 0.057 12.3 5.2 1.5 1 1 0 1 1 1 0 Rotavirus non-structural protein NSP3 DUF3135 PF11333.3 ETO00595.1 - 0.058 13.5 2.0 0.084 13.0 1.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3135) HisKA_3 PF07730.8 ETO00595.1 - 0.064 13.6 2.2 0.42 10.9 1.5 2.2 1 1 0 1 1 1 0 Histidine kinase Lge1 PF11488.3 ETO00595.1 - 0.069 13.3 4.8 0.23 11.6 0.4 2.3 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 IFT46_B_C PF12317.3 ETO00595.1 - 0.071 12.4 1.3 0.076 12.3 0.9 1.2 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal TIP120 PF08623.5 ETO00595.1 - 0.086 12.4 6.5 0.15 11.6 4.5 1.6 1 1 0 1 1 1 0 TATA-binding protein interacting (TIP20) AAA_23 PF13476.1 ETO00595.1 - 0.15 12.4 6.6 0.18 12.1 4.6 1.2 1 0 0 1 1 1 0 AAA domain Tweety PF04906.8 ETO00595.1 - 0.15 10.4 0.7 0.2 10.0 0.5 1.2 1 0 0 1 1 1 0 Tweety CesA PF11439.3 ETO00595.1 - 0.25 11.2 3.5 0.3 11.0 1.5 1.7 1 1 0 1 1 1 0 Type III secretion system filament chaperone CesA DUF1664 PF07889.7 ETO00595.1 - 0.27 11.0 7.7 0.49 10.2 5.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Pox_A_type_inc PF04508.7 ETO00595.1 - 0.34 10.8 9.0 0.75 9.7 0.8 3.4 3 1 1 4 4 3 0 Viral A-type inclusion protein repeat HR1 PF02185.11 ETO00595.1 - 0.42 10.3 8.8 1.9 8.3 6.1 2.1 1 1 0 1 1 1 0 Hr1 repeat Prefoldin PF02996.12 ETO00595.1 - 0.43 10.2 8.5 0.078 12.6 1.9 2.1 1 1 1 2 2 2 0 Prefoldin subunit LTXXQ PF07813.7 ETO00595.1 - 0.47 10.9 6.4 0.48 10.9 3.9 1.6 1 1 0 1 1 1 0 LTXXQ motif family protein DUF4094 PF13334.1 ETO00595.1 - 0.48 10.8 5.4 0.76 10.1 3.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) Syntaxin_2 PF14523.1 ETO00595.1 - 0.71 9.9 8.9 3.8 7.6 6.2 2.0 1 1 0 1 1 1 0 Syntaxin-like protein COG2 PF06148.6 ETO00595.1 - 0.96 9.3 7.0 1.7 8.5 4.1 1.8 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Phage_GP20 PF06810.6 ETO00595.1 - 1 8.7 15.0 0.15 11.4 4.6 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 NPV_P10 PF05531.7 ETO00595.1 - 1 9.6 6.7 3.3 8.0 1.9 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein MADF_DNA_bdg PF10545.4 ETO00595.1 - 1.3 9.2 5.6 20 5.4 0.1 2.7 1 1 2 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Atg14 PF10186.4 ETO00595.1 - 1.8 7.4 8.1 2 7.2 5.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4359 PF14271.1 ETO00595.1 - 2 8.8 5.1 1.2 9.5 1.7 1.9 2 1 0 2 2 1 0 Domain of unknown function (DUF4359) IncA PF04156.9 ETO00595.1 - 2 7.9 14.4 16 5.0 10.1 1.8 1 1 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 ETO00595.1 - 2.9 5.6 6.4 3.7 5.3 4.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FliT PF05400.8 ETO00595.1 - 9.1 6.7 10.4 6.4 7.2 3.5 2.2 1 1 1 2 2 2 0 Flagellar protein FliT bZIP_2 PF07716.10 ETO00595.1 - 9.4 6.1 14.2 0.68 9.7 5.2 2.4 3 0 0 3 3 2 0 Basic region leucine zipper Hexokinase_2 PF03727.11 ETO00596.1 - 0.087 12.0 0.3 0.15 11.2 0.2 1.4 1 0 0 1 1 1 0 Hexokinase Inhibitor_I34 PF10466.4 ETO00597.1 - 0.029 14.4 6.4 0.089 12.8 4.4 1.8 1 0 0 1 1 1 0 Saccharopepsin inhibitor I34 DUF3246 PF11596.3 ETO00597.1 - 0.19 10.9 14.7 0.14 11.4 9.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3246) DUF4028 PF13220.1 ETO00598.1 - 0.018 14.6 6.2 0.018 14.6 4.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4028) DUF3796 PF12676.2 ETO00598.1 - 0.079 13.1 0.6 0.079 13.1 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3796) Peptidase_S49_N PF08496.5 ETO00599.1 - 0.04 13.6 1.6 0.045 13.5 1.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PyocinActivator PF11112.3 ETO00599.1 - 0.14 11.9 0.4 0.36 10.7 0.3 1.6 1 0 0 1 1 1 0 Pyocin activator protein PrtN DMAP_binding PF06464.6 ETO00599.1 - 0.67 10.5 6.6 0.24 12.0 2.5 1.7 2 0 0 2 2 2 0 DMAP1-binding Domain DUF4661 PF15576.1 ETO00600.1 - 0.29 10.7 3.6 0.36 10.4 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) zf-C3HC4_2 PF13923.1 ETO00601.1 - 0.0012 18.8 3.4 0.013 15.4 2.3 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO00601.1 - 0.0031 17.2 3.1 0.011 15.5 2.2 1.9 1 1 0 1 1 1 1 Ring finger domain Tet_JBP PF12851.2 ETO00601.1 - 0.016 14.4 1.6 0.019 14.2 1.1 1.0 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily Cys_knot PF00007.17 ETO00601.1 - 0.2 11.7 7.5 0.25 11.4 5.2 1.3 1 0 0 1 1 1 0 Cystine-knot domain zf-C3HC4 PF00097.20 ETO00601.1 - 3.3 7.4 8.8 8.1 6.1 0.1 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) UPF0233 PF06781.7 ETO00602.1 - 0.54 9.9 2.8 0.65 9.6 0.6 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0233) zf-RING_2 PF13639.1 ETO00603.1 - 0.00027 20.6 3.3 0.0011 18.8 2.3 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO00603.1 - 0.002 18.1 3.3 0.015 15.3 2.3 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Phage_Gp23 PF10669.4 ETO00603.1 - 0.036 14.1 1.3 2.1 8.4 0.1 2.2 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Ank_2 PF12796.2 ETO00604.1 - 5.4e-11 42.6 1.2 7.9e-10 38.9 0.2 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO00604.1 - 7.2e-11 41.2 0.4 0.00023 21.0 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 ETO00604.1 - 1.5e-09 37.1 0.1 4.7e-06 26.1 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 ETO00604.1 - 6e-08 32.9 0.5 3.6e-07 30.5 0.2 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO00604.1 - 6.5e-08 32.5 1.2 1.2e-05 25.3 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) DNA_pol_E_B PF04042.11 ETO00604.1 - 0.029 13.6 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B TPR_12 PF13424.1 ETO00605.1 - 9.6e-07 28.6 0.1 0.0065 16.3 0.0 1.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO00605.1 - 3.7e-06 26.2 0.1 6.6e-06 25.5 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO00605.1 - 0.0015 18.2 0.0 0.0036 17.1 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO00605.1 - 0.0017 17.9 0.0 0.0027 17.3 0.0 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO00605.1 - 0.0036 16.9 1.1 0.0036 16.9 0.8 1.8 2 1 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.13 ETO00605.1 - 0.0065 16.3 0.4 0.0099 15.7 0.0 1.4 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_11 PF13414.1 ETO00605.1 - 0.0085 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 TPR repeat TPR_17 PF13431.1 ETO00605.1 - 0.11 12.7 0.1 0.34 11.2 0.0 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat Kelch_6 PF13964.1 ETO00606.1 - 5.9e-08 32.5 2.5 0.00051 20.0 0.2 2.4 2 1 0 2 2 2 2 Kelch motif Kelch_1 PF01344.20 ETO00606.1 - 1.8e-06 27.3 3.8 0.00027 20.4 0.5 2.2 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 ETO00606.1 - 0.001 18.7 0.4 0.14 11.9 0.0 2.2 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO00606.1 - 0.005 16.7 0.6 2.9 7.9 0.0 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 ETO00606.1 - 0.053 13.6 0.4 0.86 9.8 0.0 2.3 2 0 0 2 2 2 0 Galactose oxidase, central domain Fim-adh_lectin PF09222.5 ETO00606.1 - 0.13 11.5 0.4 0.17 11.1 0.2 1.3 1 1 0 1 1 1 0 Fimbrial adhesin F17-AG, lectin domain NLE PF08154.7 ETO00607.1 - 0.019 14.9 0.4 9.6 6.2 0.2 3.0 2 1 1 3 3 3 0 NLE (NUC135) domain DUF342 PF03961.8 ETO00609.1 - 8.8 4.6 8.0 1.1 7.6 2.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF342) LAGLIDADG_3 PF14528.1 ETO00610.1 - 1.7 8.9 5.0 4.8 7.4 3.5 2.0 1 1 0 1 1 1 0 LAGLIDADG-like domain OATP PF03137.15 ETO00610.1 - 2.3 6.1 5.6 2.5 6.0 3.9 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF2015 PF09435.5 ETO00611.1 - 0.03 14.1 0.0 0.048 13.4 0.0 1.4 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF2015) DUF1443 PF07280.6 ETO00611.1 - 0.12 11.9 1.0 0.27 10.8 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1443) Nuf2 PF03800.9 ETO00613.1 - 0.059 13.3 0.1 0.14 12.1 0.0 1.6 1 1 0 1 1 1 0 Nuf2 family WD40 PF00400.27 ETO00615.1 - 1.5e-11 43.6 0.6 3e-11 42.7 0.4 1.5 1 0 0 1 1 1 1 WD domain, G-beta repeat zf-TRAF PF02176.13 ETO00615.1 - 1.7e-05 25.0 1.7 3.9e-05 23.9 1.2 1.6 1 0 0 1 1 1 1 TRAF-type zinc finger Nup160 PF11715.3 ETO00615.1 - 0.0014 16.8 0.1 0.0014 16.8 0.1 1.5 2 0 0 2 2 2 1 Nucleoporin Nup120/160 DUF1524 PF07510.6 ETO00616.1 - 0.08 12.7 0.4 0.17 11.7 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1524) WD40 PF00400.27 ETO00617.1 - 2.1e-11 43.2 1.4 1.8e-10 40.2 0.2 2.3 2 1 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO00617.1 - 0.0081 14.3 0.1 0.0091 14.1 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Potex_coat PF06184.6 ETO00617.1 - 0.15 11.4 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Potexvirus coat protein DUF3384 PF11864.3 ETO00618.1 - 0.006 15.1 0.8 0.0066 14.9 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Kinesin-relat_1 PF12711.2 ETO00618.1 - 0.052 13.9 1.0 0.059 13.7 0.7 1.2 1 0 0 1 1 1 0 Kinesin motor Stap_Strp_toxin PF01123.15 ETO00618.1 - 0.32 11.5 2.4 0.44 11.0 1.7 1.4 1 1 0 1 1 1 0 Staphylococcal/Streptococcal toxin, OB-fold domain CCDC144C PF14915.1 ETO00618.1 - 0.56 9.0 8.1 0.64 8.8 5.6 1.0 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region zf-RING_2 PF13639.1 ETO00619.1 - 0.0059 16.4 1.6 0.025 14.4 1.1 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO00619.1 - 0.012 15.6 1.3 0.12 12.4 0.9 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2607 PF10795.4 ETO00619.1 - 0.051 13.3 0.8 8.4 6.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2607) zf-RING-like PF08746.6 ETO00619.1 - 0.96 9.5 5.1 4.8 7.2 3.6 2.3 1 1 0 1 1 1 0 RING-like domain zf-GRF PF06839.7 ETO00619.1 - 1.4 8.9 5.0 0.27 11.1 0.4 2.1 2 0 0 2 2 2 0 GRF zinc finger FmdE PF02663.9 ETO00621.1 - 1.1 9.2 6.2 0.94 9.3 2.9 1.9 1 1 1 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon SprA-related PF12118.3 ETO00621.1 - 1.3 8.2 14.1 1.6 8.0 9.8 1.1 1 0 0 1 1 1 0 SprA-related family AAA_23 PF13476.1 ETO00621.1 - 2.4 8.4 26.1 3.3 7.9 18.1 1.2 1 0 0 1 1 1 0 AAA domain Bac_small_YrzI PF09501.5 ETO00621.1 - 7.1 6.6 16.1 3.2 7.7 0.6 3.6 2 1 2 4 4 4 0 Probable sporulation protein (Bac_small_yrzI) fn3 PF00041.16 ETO00622.1 - 0.0001 22.3 0.0 0.00062 19.8 0.0 2.1 2 0 0 2 2 2 1 Fibronectin type III domain CDC45 PF02724.9 ETO00622.1 - 0.029 12.3 3.4 0.028 12.4 2.3 1.1 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.5 ETO00622.1 - 0.057 13.6 3.3 0.11 12.8 2.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Atrophin-1 PF03154.10 ETO00622.1 - 0.08 11.0 2.8 0.097 10.8 1.9 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF2722 PF10846.3 ETO00622.1 - 0.53 9.2 5.3 0.58 9.1 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Vfa1 PF08432.5 ETO00622.1 - 4.4 7.3 19.5 0.35 10.8 10.1 1.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 U79_P34 PF03064.11 ETO00622.1 - 6.7 6.1 14.4 9.5 5.6 10.0 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 ASFV_p27 PF06556.6 ETO00623.1 - 0.071 13.0 0.3 0.15 11.9 0.0 1.6 2 0 0 2 2 2 0 IAP-like protein p27 C-terminus DUF2987 PF11205.3 ETO00624.1 - 0.042 13.5 1.4 2.8 7.6 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2987) ATP_synth_reg PF14960.1 ETO00624.1 - 0.051 12.7 1.8 0.97 8.6 0.3 2.4 2 0 0 2 2 2 0 ATP synthase regulation Tir_receptor_N PF07490.6 ETO00624.1 - 0.2 11.2 1.1 0.25 10.9 0.8 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus RNase_H PF00075.19 ETO00626.1 - 5.6e-13 49.3 0.0 1.2e-12 48.3 0.0 1.5 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.1 ETO00626.1 - 0.03 14.1 0.0 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like WD40 PF00400.27 ETO00627.1 - 4.3e-19 67.6 1.9 9.4e-10 38.0 0.6 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO00627.1 - 0.00012 20.4 0.1 0.035 12.2 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF851 PF05867.6 ETO00627.1 - 0.11 11.6 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF851) Kelch_5 PF13854.1 ETO00629.1 - 0.13 12.2 0.2 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 Kelch motif DUF1510 PF07423.6 ETO00630.1 - 0.013 14.8 12.6 0.013 14.8 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Daxx PF03344.10 ETO00630.1 - 0.03 12.8 19.8 0.031 12.7 13.7 1.0 1 0 0 1 1 1 0 Daxx Family DUF2052 PF09747.4 ETO00630.1 - 0.034 14.0 13.2 0.034 14.0 9.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DDRGK PF09756.4 ETO00630.1 - 0.06 12.7 14.1 0.066 12.6 9.8 1.1 1 0 0 1 1 1 0 DDRGK domain DDHD PF02862.12 ETO00630.1 - 0.074 12.8 4.1 0.096 12.4 2.9 1.2 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.9 ETO00630.1 - 0.083 10.9 8.8 0.073 11.1 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Spore_coat_CotO PF14153.1 ETO00630.1 - 0.11 11.8 12.6 0.1 12.0 8.7 1.1 1 0 0 1 1 1 0 Spore coat protein CotO SDA1 PF05285.7 ETO00630.1 - 0.13 11.5 15.2 0.14 11.4 10.6 1.0 1 0 0 1 1 1 0 SDA1 AIF_C PF14721.1 ETO00630.1 - 0.13 12.4 2.7 0.14 12.3 1.9 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Nop14 PF04147.7 ETO00630.1 - 0.22 9.4 17.6 0.24 9.2 12.2 1.0 1 0 0 1 1 1 0 Nop14-like family VID27 PF08553.5 ETO00630.1 - 0.29 9.3 13.5 0.28 9.3 9.4 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein TEX19 PF15553.1 ETO00630.1 - 0.34 10.7 12.6 0.38 10.6 8.7 1.1 1 0 0 1 1 1 0 Testis-expressed protein 19 SAPS PF04499.10 ETO00630.1 - 0.35 9.4 6.5 0.34 9.4 4.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pox_Ag35 PF03286.9 ETO00630.1 - 0.39 10.2 11.7 0.44 10.0 8.1 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Tim54 PF11711.3 ETO00630.1 - 0.46 9.0 8.1 0.44 9.0 5.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 XAP5 PF04921.9 ETO00630.1 - 0.47 9.9 7.2 0.53 9.8 5.0 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator NARP1 PF12569.3 ETO00630.1 - 0.63 8.7 8.8 0.73 8.5 6.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Usp PF00582.21 ETO00630.1 - 0.71 10.0 7.8 0.84 9.8 5.4 1.2 1 0 0 1 1 1 0 Universal stress protein family FAM176 PF14851.1 ETO00630.1 - 0.76 9.4 10.4 1 9.0 7.2 1.2 1 0 0 1 1 1 0 FAM176 family CENP-T PF15511.1 ETO00630.1 - 0.85 8.7 11.7 0.79 8.9 8.1 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF2722 PF10846.3 ETO00630.1 - 0.89 8.5 6.2 0.87 8.5 4.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Pox_RNA_Pol_19 PF05320.7 ETO00630.1 - 0.96 9.1 10.1 1.4 8.6 7.0 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF3306 PF11748.3 ETO00630.1 - 1.2 9.7 13.4 1.7 9.3 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) DUF4045 PF13254.1 ETO00630.1 - 1.2 8.2 5.4 1.2 8.3 3.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) RRN3 PF05327.6 ETO00630.1 - 1.4 6.9 9.3 1.2 7.1 6.4 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Vfa1 PF08432.5 ETO00630.1 - 1.7 8.6 12.0 2.2 8.3 8.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Prothymosin PF03247.9 ETO00630.1 - 1.7 8.8 33.5 2.6 8.2 23.2 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family Ycf1 PF05758.7 ETO00630.1 - 1.8 6.2 10.8 1.8 6.1 7.5 1.0 1 0 0 1 1 1 0 Ycf1 DUF2072 PF09845.4 ETO00630.1 - 1.9 8.4 9.6 2.2 8.1 6.6 1.3 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Tom37_C PF11801.3 ETO00630.1 - 2 8.2 4.6 2 8.2 3.2 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain DUF4589 PF15252.1 ETO00630.1 - 2.1 8.0 6.4 2.6 7.8 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) PBP1_TM PF14812.1 ETO00630.1 - 2.3 8.5 11.7 3.4 8.0 8.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Plasmodium_Vir PF05795.6 ETO00630.1 - 3.2 6.8 6.5 3.7 6.6 4.5 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein eIF-3c_N PF05470.7 ETO00630.1 - 3.3 5.6 9.1 3.4 5.6 6.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus YqfQ PF14181.1 ETO00630.1 - 3.7 7.5 14.3 4.9 7.1 9.9 1.1 1 0 0 1 1 1 0 YqfQ-like protein Cytomega_UL84 PF06284.6 ETO00630.1 - 4.1 5.6 9.7 4.7 5.4 6.7 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein TRAP_alpha PF03896.11 ETO00630.1 - 4.5 6.1 15.7 5 6.0 10.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sporozoite_P67 PF05642.6 ETO00630.1 - 5.1 4.8 10.5 5.6 4.7 7.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Afi1 PF07792.7 ETO00630.1 - 6 6.8 7.6 7.7 6.5 5.2 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Sigma70_ner PF04546.8 ETO00630.1 - 6.9 6.2 17.5 8.7 5.8 12.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Prog_receptor PF02161.10 ETO00630.1 - 7 5.3 10.9 8 5.1 7.5 1.1 1 0 0 1 1 1 0 Progesterone receptor DUF3530 PF12048.3 ETO00630.1 - 8.7 5.2 14.5 11 4.9 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) WD40 PF00400.27 ETO00632.1 - 4.6e-27 92.8 3.5 3.2e-10 39.5 0.0 4.3 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO00632.1 - 3e-06 25.6 0.8 0.059 11.4 0.1 2.9 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO00632.1 - 0.001 17.9 2.0 0.1 11.3 1.4 2.9 1 1 0 1 1 1 1 Nup133 N terminal like KduI PF04962.7 ETO00632.1 - 0.038 13.0 0.0 0.047 12.7 0.0 1.1 1 0 0 1 1 1 0 KduI/IolB family NACHT PF05729.7 ETO00633.1 - 2e-09 37.2 0.0 2.5e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO00633.1 - 1.4e-06 28.6 0.1 1.4e-06 28.6 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETO00633.1 - 2.8e-05 24.2 0.0 4.9e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO00633.1 - 9.1e-05 23.2 0.1 0.00022 22.0 0.0 1.7 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 ETO00633.1 - 0.0028 17.8 0.5 0.021 14.9 0.1 2.4 1 1 0 1 1 1 1 RNA helicase DUF258 PF03193.11 ETO00633.1 - 0.0034 16.5 0.0 0.004 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ATP_bind_2 PF03668.10 ETO00633.1 - 0.0043 16.1 0.0 0.0059 15.7 0.0 1.2 1 0 0 1 1 1 1 P-loop ATPase protein family DUF2075 PF09848.4 ETO00633.1 - 0.0065 15.4 0.0 0.0065 15.4 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) G-alpha PF00503.15 ETO00633.1 - 0.0069 15.1 4.5 0.0069 15.1 3.1 1.9 1 1 0 2 2 2 1 G-protein alpha subunit ABC_tran PF00005.22 ETO00633.1 - 0.0076 16.5 0.6 0.013 15.7 0.3 1.6 1 1 0 1 1 1 1 ABC transporter AAA_14 PF13173.1 ETO00633.1 - 0.02 14.8 0.9 0.04 13.8 0.6 1.6 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 ETO00633.1 - 0.023 14.5 0.0 0.052 13.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 ETO00633.1 - 0.024 13.7 0.1 0.037 13.1 0.1 1.6 1 1 0 1 1 1 0 Zeta toxin AAA_29 PF13555.1 ETO00633.1 - 0.024 14.1 0.1 0.049 13.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.21 ETO00633.1 - 0.026 14.0 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 ETO00633.1 - 0.027 13.5 0.2 0.074 12.1 0.0 1.7 1 1 1 2 2 2 0 KaiC AAA PF00004.24 ETO00633.1 - 0.029 14.5 0.0 0.048 13.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) VirE PF05272.6 ETO00633.1 - 0.031 13.7 0.1 0.049 13.0 0.1 1.5 1 1 0 1 1 1 0 Virulence-associated protein E UPF0079 PF02367.12 ETO00633.1 - 0.037 13.6 0.0 0.058 13.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 ETO00633.1 - 0.07 12.5 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_30 PF13604.1 ETO00633.1 - 0.095 12.2 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 ETO00633.1 - 0.11 11.4 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein PRK PF00485.13 ETO00633.1 - 0.17 11.4 0.0 0.17 11.4 0.0 1.7 2 1 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DNA_pol3_delta2 PF13177.1 ETO00633.1 - 0.17 11.5 5.1 0.046 13.3 0.8 1.8 1 1 1 2 2 2 0 DNA polymerase III, delta subunit HsdM_N PF12161.3 ETO00633.1 - 1.2 9.5 9.3 2.6 8.4 6.4 1.4 1 1 0 1 1 1 0 HsdM N-terminal domain Peptidase_S49_N PF08496.5 ETO00633.1 - 1.6 8.4 7.7 1.3 8.7 4.4 1.5 1 1 0 1 1 1 0 Peptidase family S49 N-terminal ALS2CR8 PF15299.1 ETO00633.1 - 2.3 7.7 11.2 2.6 7.5 0.0 2.1 1 1 1 2 2 2 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 DUF3899 PF13038.1 ETO00633.1 - 6.3 7.0 6.2 26 5.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Lant_dehyd_C PF04738.8 ETO00635.1 - 0.012 13.8 0.0 0.022 13.0 0.0 1.3 1 0 0 1 1 1 0 Lantibiotic dehydratase, C terminus DUF4258 PF14076.1 ETO00635.1 - 0.07 13.1 0.0 0.33 11.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4258) Kelch_1 PF01344.20 ETO00636.1 - 5.1e-12 45.1 2.3 1.5e-07 30.8 0.6 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.10 ETO00636.1 - 2.8e-09 36.3 0.5 6.5e-06 25.6 0.1 2.6 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO00636.1 - 1e-08 34.9 0.4 0.00033 20.6 0.2 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.1 ETO00636.1 - 1.1e-07 31.6 0.0 0.00041 20.2 0.1 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 ETO00636.1 - 7.1e-07 29.2 0.3 0.00034 20.6 0.1 2.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO00636.1 - 2.1e-06 27.3 0.2 0.0047 16.6 0.1 2.3 2 0 0 2 2 2 2 Galactose oxidase, central domain PGC7_Stella PF15549.1 ETO00639.1 - 0.13 12.2 0.5 0.14 12.0 0.3 1.1 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain DUF2117 PF09890.4 ETO00639.1 - 0.19 10.9 1.9 0.25 10.5 1.0 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2117) SCF PF02404.10 ETO00640.1 - 0.00011 21.5 1.0 0.01 15.0 0.1 2.2 2 0 0 2 2 2 2 Stem cell factor DUF4561 PF15120.1 ETO00640.1 - 0.0076 15.7 1.7 1.2 8.6 0.1 2.6 2 1 0 3 3 3 2 Domain of unknown function (DUF4561) DUF4269 PF14091.1 ETO00640.1 - 0.13 12.1 0.8 1 9.2 0.0 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4269) U-box PF04564.10 ETO00642.1 - 1.2e-11 44.3 0.0 2.8e-11 43.2 0.0 1.6 1 1 0 1 1 1 1 U-box domain DUF1043 PF06295.7 ETO00642.1 - 0.063 12.9 0.1 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) SAM_1 PF00536.25 ETO00642.1 - 0.086 13.0 0.8 0.13 12.4 0.1 1.6 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) DUF2124 PF09897.4 ETO00642.1 - 0.1 12.2 0.2 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2124) Beta_helix PF13229.1 ETO00643.1 - 0.11 12.2 12.7 0.23 11.2 8.8 1.6 1 1 0 1 1 1 0 Right handed beta helix region PDE8 PF08629.5 ETO00644.1 - 0.09 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 PDE8 phosphodiesterase DUF1132 PF06575.7 ETO00645.1 - 0.11 12.7 1.4 0.34 11.2 1.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1132) WD40 PF00400.27 ETO00647.1 - 5.9e-22 76.6 1.6 2.6e-10 39.7 0.1 3.5 3 1 0 3 3 3 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 ETO00647.1 - 0.0061 16.3 0.5 0.06 13.1 0.3 2.2 1 1 0 1 1 1 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 ETO00647.1 - 0.02 13.0 0.1 0.99 7.4 0.0 2.0 1 1 0 2 2 2 0 Nucleoporin Nup120/160 DUF4550 PF15084.1 ETO00648.1 - 0.15 12.2 0.5 0.46 10.6 0.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4550) ABC_membrane_2 PF06472.10 ETO00649.1 - 0.066 12.3 3.4 0.079 12.0 2.4 1.1 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 SR-25 PF10500.4 ETO00650.1 - 0.16 11.4 24.3 0.17 11.3 16.8 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ribosomal_L6e PF01159.14 ETO00650.1 - 0.23 11.6 15.7 0.26 11.5 10.9 1.0 1 0 0 1 1 1 0 Ribosomal protein L6e BRF1 PF07741.8 ETO00650.1 - 0.79 9.9 16.1 0.85 9.8 11.2 1.1 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF1764 PF08576.5 ETO00650.1 - 0.97 10.2 13.2 0.99 10.2 9.1 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) FCP1_C PF09309.5 ETO00650.1 - 1.3 8.2 8.7 1.3 8.2 6.0 1.0 1 0 0 1 1 1 0 FCP1, C-terminal DUF3807 PF12720.2 ETO00650.1 - 1.3 9.1 11.5 1.3 9.1 8.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) GAGA_bind PF06217.7 ETO00650.1 - 1.5 8.6 16.4 1.6 8.6 11.4 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2956 PF11169.3 ETO00650.1 - 2.7 8.0 19.4 2.8 7.9 13.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) SpoVR PF04293.8 ETO00650.1 - 2.8 6.2 6.9 3 6.1 4.7 1.0 1 0 0 1 1 1 0 SpoVR like protein FAM176 PF14851.1 ETO00650.1 - 2.8 7.5 5.7 2.8 7.6 3.9 1.1 1 0 0 1 1 1 0 FAM176 family Vfa1 PF08432.5 ETO00650.1 - 3 7.8 20.1 3.1 7.7 13.9 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 U79_P34 PF03064.11 ETO00650.1 - 3.8 6.9 14.2 4 6.8 9.9 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF2514 PF10721.4 ETO00650.1 - 4 7.1 6.1 4.6 6.9 4.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Mre11_DNA_bind PF04152.9 ETO00650.1 - 4.1 7.2 10.9 4.4 7.1 7.5 1.1 1 0 0 1 1 1 0 Mre11 DNA-binding presumed domain RR_TM4-6 PF06459.7 ETO00650.1 - 4.1 7.2 10.5 4.1 7.2 7.3 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3464 PF11947.3 ETO00650.1 - 4.5 6.7 10.5 4.5 6.7 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) FAM60A PF15396.1 ETO00650.1 - 4.5 6.9 14.5 4.6 6.9 10.0 1.0 1 0 0 1 1 1 0 Protein Family FAM60A EIIBC-GUT_N PF03612.9 ETO00650.1 - 4.6 6.8 6.2 4.6 6.8 4.3 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Rtf2 PF04641.7 ETO00650.1 - 4.9 6.2 17.0 5.7 6.0 11.8 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger DDHD PF02862.12 ETO00650.1 - 5.8 6.6 7.5 5.4 6.7 5.2 1.0 1 0 0 1 1 1 0 DDHD domain CMS1 PF14617.1 ETO00650.1 - 5.9 5.8 17.1 6.8 5.6 11.8 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Eapp_C PF10238.4 ETO00650.1 - 6 6.7 9.8 6.3 6.7 6.8 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein FLO_LFY PF01698.11 ETO00650.1 - 6.9 5.4 12.0 6.9 5.4 8.3 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein PH_10 PF15411.1 ETO00650.1 - 7.8 6.7 10.7 10 6.3 7.4 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain DUF755 PF05501.6 ETO00650.1 - 8 6.5 21.2 8.9 6.3 14.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Peptidase_S49_N PF08496.5 ETO00650.1 - 9.2 6.0 17.8 10 5.9 12.3 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Agouti PF05039.7 ETO00650.1 - 9.3 6.6 8.6 10 6.5 6.0 1.2 1 0 0 1 1 1 0 Agouti protein NPR3 PF03666.8 ETO00650.1 - 9.6 4.6 12.8 10 4.5 8.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 NACHT PF05729.7 ETO00652.1 - 1.6e-12 47.4 0.0 2.5e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETO00652.1 - 4.2e-05 23.6 0.0 0.00093 19.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.17 ETO00652.1 - 0.00019 20.3 0.4 0.00037 19.4 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.1 ETO00652.1 - 0.0021 18.0 0.1 0.0097 15.9 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 ETO00652.1 - 0.0031 17.6 0.2 0.47 10.6 0.0 3.2 3 0 0 3 3 3 1 RNA helicase DUF2075 PF09848.4 ETO00652.1 - 0.0047 15.9 0.7 0.019 13.9 0.0 2.3 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 ETO00652.1 - 0.025 14.3 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 ETO00652.1 - 0.044 13.3 0.3 0.4 10.2 0.0 2.3 2 1 1 3 3 3 0 AAA domain AAA_18 PF13238.1 ETO00652.1 - 0.082 13.2 3.8 0.086 13.1 0.0 2.5 3 0 0 3 3 3 0 AAA domain Torsin PF06309.6 ETO00652.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Torsin DRY_EERY PF09750.4 ETO00652.1 - 0.59 10.2 4.5 1.4 9.0 1.3 2.4 1 1 1 2 2 2 0 Alternative splicing regulator AAA_17 PF13207.1 ETO00652.1 - 0.61 10.9 4.9 1.2 9.9 0.4 3.1 2 2 0 2 2 2 0 AAA domain Myb_DNA-bind_4 PF13837.1 ETO00652.1 - 4.6 7.4 10.0 5.3 7.2 1.8 2.7 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain AAA_5 PF07728.9 ETO00654.1 - 1.6e-05 24.6 0.0 5.6e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 ETO00654.1 - 3.8e-05 23.5 0.0 0.00049 20.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 ETO00654.1 - 4.3e-05 23.7 0.0 0.00017 21.7 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 ETO00654.1 - 0.00023 20.2 0.1 0.00044 19.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 ETO00654.1 - 0.00037 20.7 0.2 0.0014 18.9 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_17 PF13207.1 ETO00654.1 - 0.00059 20.6 0.0 0.04 14.7 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETO00654.1 - 0.0041 17.4 0.5 0.024 14.9 0.1 2.6 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 ETO00654.1 - 0.0055 16.8 0.1 0.031 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 ETO00654.1 - 0.013 15.2 0.2 0.064 12.9 0.0 2.4 1 1 1 2 2 2 0 Archaeal ATPase RNA_helicase PF00910.17 ETO00654.1 - 0.016 15.3 0.1 0.077 13.1 0.0 2.3 2 0 0 2 2 1 0 RNA helicase AAA_16 PF13191.1 ETO00654.1 - 0.016 15.2 0.0 0.13 12.2 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 ETO00654.1 - 0.017 14.7 0.2 0.17 11.4 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 ETO00654.1 - 0.02 14.3 0.0 0.19 11.2 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain MCM PF00493.18 ETO00654.1 - 0.022 13.6 0.1 0.069 11.9 0.0 1.8 2 0 0 2 2 2 0 MCM2/3/5 family AAA_2 PF07724.9 ETO00654.1 - 0.043 13.7 0.1 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) DUF4066 PF13278.1 ETO00654.1 - 0.05 12.8 0.1 0.13 11.4 0.0 1.7 2 0 0 2 2 2 0 Putative amidotransferase Coagulin PF02035.10 ETO00661.1 - 0.014 15.0 2.6 0.019 14.6 1.8 1.2 1 0 0 1 1 1 0 Coagulin zf-CCHC PF00098.18 ETO00661.1 - 0.037 13.9 1.0 0.037 13.9 0.7 2.6 2 0 0 2 2 2 0 Zinc knuckle DUF2361 PF10153.4 ETO00662.1 - 3.1 8.0 12.2 0.26 11.4 4.1 2.1 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2361) LRR_5 PF13306.1 ETO00664.1 - 0.0028 17.3 3.6 0.023 14.4 1.6 1.8 1 1 0 1 1 1 1 Leucine rich repeats (6 copies) DUF365 PF04033.7 ETO00664.1 - 0.23 11.4 2.6 0.34 10.9 1.5 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF365) CDC45 PF02724.9 ETO00665.1 - 0.0011 17.0 13.4 0.0015 16.6 9.3 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF2624 PF11116.3 ETO00665.1 - 0.06 13.8 0.2 0.13 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) Zip PF02535.17 ETO00665.1 - 0.51 9.2 5.3 0.61 9.0 3.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4519 PF15012.1 ETO00665.1 - 0.63 10.0 3.3 1.3 9.0 2.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Hid1 PF12722.2 ETO00665.1 - 1.2 6.7 11.3 1.4 6.5 7.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.11 ETO00665.1 - 1.8 8.3 4.5 2.3 8.0 3.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Dsh_C PF12316.3 ETO00665.1 - 2.8 8.0 10.4 3.7 7.6 7.2 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Myc_target_1 PF15179.1 ETO00667.1 - 0.02 14.4 0.4 0.023 14.2 0.2 1.2 1 0 0 1 1 1 0 Myc target protein 1 DUF1974 PF09317.6 ETO00667.1 - 0.077 12.3 0.1 0.086 12.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) Tho2 PF11262.3 ETO00669.1 - 0.0066 15.5 0.5 0.0092 15.0 0.3 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 RdgC PF04381.7 ETO00670.1 - 0.04 12.8 1.4 0.15 10.9 0.2 2.0 2 0 0 2 2 2 0 Putative exonuclease, RdgC HSP90 PF00183.13 ETO00671.1 - 5.4e-71 239.5 14.1 5.2e-69 233.0 9.8 2.0 1 1 0 1 1 1 1 Hsp90 protein DUF619 PF04768.8 ETO00671.1 - 0.0038 16.6 0.2 0.0064 15.9 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF619) PilN PF05137.8 ETO00671.1 - 0.015 15.0 0.1 0.039 13.7 0.0 1.7 2 0 0 2 2 2 0 Fimbrial assembly protein (PilN) Ferritin-like PF12902.2 ETO00672.1 - 0.3 10.6 4.2 0.39 10.2 2.9 1.1 1 0 0 1 1 1 0 Ferritin-like GSG-1 PF07803.6 ETO00672.1 - 0.44 10.1 2.4 18 4.9 0.8 2.3 1 1 0 2 2 2 0 GSG1-like protein DUF1049 PF06305.6 ETO00675.1 - 0.042 13.3 0.2 0.1 12.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) WEMBL PF05701.6 ETO00676.1 - 2.2e-05 23.1 34.1 9.1e-05 21.1 23.6 1.9 1 1 0 1 1 1 1 Weak chloroplast movement under blue light EzrA PF06160.7 ETO00676.1 - 6.5e-05 21.3 14.4 6.5e-05 21.3 10.0 2.0 1 1 1 2 2 2 1 Septation ring formation regulator, EzrA AAA_27 PF13514.1 ETO00676.1 - 0.0024 15.6 23.2 0.0026 15.5 16.0 1.0 1 0 0 1 1 1 1 AAA domain Cast PF10174.4 ETO00676.1 - 0.0029 15.7 31.7 0.019 13.0 10.4 1.9 1 1 1 2 2 2 2 RIM-binding protein of the cytomatrix active zone Golgin_A5 PF09787.4 ETO00676.1 - 0.0098 14.4 18.4 0.1 11.1 2.8 2.0 1 1 1 2 2 2 2 Golgin subfamily A member 5 CENP-F_leu_zip PF10473.4 ETO00676.1 - 0.014 15.2 36.1 0.072 12.9 7.5 2.8 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sec8_exocyst PF04048.9 ETO00676.1 - 0.017 14.7 16.9 0.65 9.6 1.3 3.1 1 1 1 3 3 3 0 Sec8 exocyst complex component specific domain DUF2524 PF10732.4 ETO00676.1 - 0.027 14.5 13.5 3 8.0 0.1 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2524) Filament PF00038.16 ETO00676.1 - 0.043 13.2 24.5 0.21 10.9 9.5 2.2 1 1 1 2 2 2 0 Intermediate filament protein Spc7 PF08317.6 ETO00676.1 - 0.048 12.3 29.1 0.37 9.3 5.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein TUDOR PF00567.19 ETO00676.1 - 0.077 12.8 0.5 0.32 10.8 0.0 1.9 1 1 1 2 2 2 0 Tudor domain GAS PF13851.1 ETO00676.1 - 0.17 11.0 33.2 0.049 12.8 6.4 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 ETO00676.1 - 0.18 11.5 32.6 2 8.1 15.7 3.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FliJ PF02050.11 ETO00676.1 - 0.19 11.7 18.8 0.87 9.6 9.4 2.4 1 1 1 2 2 2 0 Flagellar FliJ protein Prominin PF05478.6 ETO00676.1 - 0.24 8.9 12.4 0.36 8.3 8.6 1.2 1 0 0 1 1 1 0 Prominin Seryl_tRNA_N PF02403.17 ETO00676.1 - 0.25 11.3 29.1 0.65 10.0 9.5 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TBPIP PF07106.8 ETO00676.1 - 0.3 10.6 28.8 1 8.9 7.0 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) APG6 PF04111.7 ETO00676.1 - 0.33 9.9 34.2 1.5 7.8 10.9 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 MAD PF05557.8 ETO00676.1 - 0.4 8.7 30.3 0.41 8.6 7.7 1.9 1 1 1 2 2 2 0 Mitotic checkpoint protein DUF1043 PF06295.7 ETO00676.1 - 0.63 9.6 23.4 4 7.0 0.9 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1043) DUF3763 PF12592.3 ETO00676.1 - 0.73 9.5 9.7 1.8 8.2 0.4 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF3763) DUF3584 PF12128.3 ETO00676.1 - 0.75 7.0 25.5 0.34 8.1 2.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Vps5 PF09325.5 ETO00676.1 - 0.76 8.9 23.0 2 7.6 5.5 2.3 1 1 1 2 2 2 0 Vps5 C terminal like Cas_Csa4 PF09703.5 ETO00676.1 - 0.8 8.6 6.6 0.93 8.3 4.5 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa4) ADIP PF11559.3 ETO00676.1 - 0.81 9.5 32.0 0.24 11.2 7.3 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF745 PF05335.8 ETO00676.1 - 0.94 8.9 18.6 11 5.4 1.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Imm42 PF15601.1 ETO00676.1 - 0.95 8.8 16.3 4.2 6.7 1.7 4.0 1 1 3 4 4 4 0 Immunity protein 42 COG2 PF06148.6 ETO00676.1 - 1.4 8.7 15.3 1.7 8.5 0.9 3.0 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 MCPsignal PF00015.16 ETO00676.1 - 1.5 8.3 12.9 11 5.4 0.3 2.0 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3450 PF11932.3 ETO00676.1 - 2 7.6 18.0 0.5 9.5 4.5 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) TMEM247 PF15444.1 ETO00676.1 - 2.2 8.0 17.8 2.8 7.7 3.8 3.1 1 1 2 3 3 3 0 Transmembrane protein 247 IncA PF04156.9 ETO00676.1 - 2.9 7.4 26.2 5.5 6.5 4.5 2.1 1 1 1 2 2 2 0 IncA protein Reo_sigmaC PF04582.7 ETO00676.1 - 3.6 6.6 5.0 25 3.9 0.3 2.4 1 1 0 2 2 2 0 Reovirus sigma C capsid protein FlaC_arch PF05377.6 ETO00676.1 - 4.1 7.3 21.3 9.5 6.2 3.3 4.1 2 2 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF4201 PF13870.1 ETO00676.1 - 4.4 6.7 31.9 6.7 6.1 4.4 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) IFT57 PF10498.4 ETO00676.1 - 5.2 5.7 24.6 38 2.8 17.0 1.9 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 DegS PF05384.6 ETO00676.1 - 5.6 6.1 21.8 22 4.1 2.2 2.9 1 1 2 3 3 3 0 Sensor protein DegS DUF972 PF06156.8 ETO00676.1 - 5.7 7.3 27.7 10 6.5 8.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Laminin_II PF06009.7 ETO00676.1 - 6 6.6 18.9 1.3e+02 2.2 8.6 2.7 1 1 1 2 2 2 0 Laminin Domain II ATP-synt_B PF00430.13 ETO00676.1 - 6.7 6.5 24.7 2.6 7.8 1.2 3.1 1 1 2 3 3 3 0 ATP synthase B/B' CF(0) Flagellin_C PF00700.16 ETO00676.1 - 7.6 6.7 8.7 12 6.1 0.0 3.2 1 1 1 3 3 3 0 Bacterial flagellin C-terminal helical region DUF4140 PF13600.1 ETO00676.1 - 8.2 6.9 20.2 8.7 6.8 1.7 3.3 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) OEP PF02321.13 ETO00676.1 - 8.3 5.9 9.9 8.6 5.8 5.4 2.1 1 1 1 2 2 2 0 Outer membrane efflux protein BPL_N PF09825.4 ETO00676.1 - 8.6 5.0 10.3 10 4.8 7.1 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal DUF3391 PF11871.3 ETO00676.1 - 9.5 6.4 15.9 8.3 6.6 2.7 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) DUF4398 PF14346.1 ETO00676.1 - 9.7 6.3 19.0 3.9 7.5 0.8 3.3 1 1 1 2 2 1 0 Domain of unknown function (DUF4398) RNB PF00773.14 ETO00677.1 - 0.057 12.6 0.0 0.057 12.6 0.0 1.0 1 0 0 1 1 1 0 RNB domain TLD PF07534.11 ETO00678.1 - 2.1e-12 47.1 0.7 3.9e-12 46.3 0.5 1.4 1 0 0 1 1 1 1 TLD ART PF01129.13 ETO00678.1 - 0.023 13.7 0.0 0.042 12.9 0.0 1.4 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase Tubulin_C PF03953.12 ETO00679.1 - 9.5e-28 96.7 0.0 1.3e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 ETO00679.1 - 3.1e-07 30.4 0.0 5.7e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain tRNA-synt_1c_C PF03950.13 ETO00679.1 - 0.0087 15.7 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain TPR_12 PF13424.1 ETO00680.1 - 3.3e-67 222.3 21.3 3.5e-25 87.7 0.7 3.7 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO00680.1 - 1.1e-32 111.5 37.6 1.6e-14 53.2 2.9 4.0 2 1 2 4 4 4 4 TPR repeat TPR_10 PF13374.1 ETO00680.1 - 1.2e-32 110.8 0.0 1e-06 28.4 0.0 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO00680.1 - 1.9e-31 106.3 36.5 1.2e-08 34.1 1.3 5.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO00680.1 - 5e-31 104.0 6.5 2.7e-07 29.8 0.0 4.7 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO00680.1 - 2.5e-22 76.9 20.2 3.5e-05 23.3 0.4 5.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO00680.1 - 1.2e-21 74.8 34.5 1.1e-06 28.0 2.0 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETO00680.1 - 2e-15 55.6 13.0 0.0011 19.0 0.1 6.0 4 1 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO00680.1 - 1.8e-12 47.5 0.1 0.054 14.1 0.0 4.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO00680.1 - 3.2e-10 39.7 0.0 0.69 10.7 0.0 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO00680.1 - 2.3e-09 37.1 4.5 0.044 14.2 0.2 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO00680.1 - 9e-09 35.3 13.6 0.00018 21.5 3.6 4.3 1 1 4 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.1 ETO00680.1 - 2.7e-07 30.0 7.2 0.00054 19.1 1.8 2.6 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_3 PF07720.7 ETO00680.1 - 9.8e-07 28.4 25.0 0.027 14.2 0.1 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat RPN7 PF10602.4 ETO00680.1 - 3.2e-05 23.4 7.9 0.019 14.3 0.2 3.5 1 1 2 3 3 3 2 26S proteasome subunit RPN7 TPR_19 PF14559.1 ETO00680.1 - 0.0008 19.7 2.6 0.22 11.8 0.2 3.8 2 1 2 4 4 4 2 Tetratricopeptide repeat Sel1 PF08238.7 ETO00680.1 - 0.00087 19.8 11.6 2.1 9.1 0.1 5.0 5 0 0 5 5 5 1 Sel1 repeat PPR PF01535.15 ETO00680.1 - 0.0015 18.3 10.1 1 9.5 0.2 5.4 5 0 0 5 5 5 1 PPR repeat DUF627 PF04781.7 ETO00680.1 - 0.0018 17.8 6.2 2.4 7.8 0.0 4.0 2 1 3 5 5 4 2 Protein of unknown function (DUF627) UPF0223 PF05256.7 ETO00680.1 - 0.028 14.5 1.8 8.6 6.5 0.1 2.8 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0223) MIT PF04212.13 ETO00680.1 - 0.043 13.7 16.7 6.6 6.7 0.4 4.5 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain Ten1_2 PF15490.1 ETO00680.1 - 0.061 12.9 0.1 9.9 5.7 0.0 3.8 1 1 3 4 4 4 0 Telomere-capping, CST complex subunit DUF2225 PF09986.4 ETO00680.1 - 0.17 11.3 8.9 0.41 10.0 1.4 2.8 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF357 PF04010.8 ETO00680.1 - 0.23 11.1 7.9 14 5.4 0.1 3.8 2 1 2 4 4 4 0 Protein of unknown function (DUF357) Mob_Pre PF01076.14 ETO00680.1 - 0.68 9.5 6.9 0.18 11.3 0.8 2.1 1 1 1 2 2 2 0 Plasmid recombination enzyme Ubiq-assoc PF09145.5 ETO00680.1 - 0.95 9.3 19.6 10 6.0 0.2 6.2 3 3 3 6 6 6 0 Ubiquitin-associated DUF3450 PF11932.3 ETO00680.1 - 3.1 6.9 10.0 19 4.3 0.1 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) TPR_12 PF13424.1 ETO00681.1 - 1.9e-53 178.2 10.9 4.6e-20 71.3 0.6 3.0 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO00681.1 - 3.1e-33 110.9 6.1 1.1e-08 34.2 0.1 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO00681.1 - 1.8e-31 107.1 0.0 1.6e-07 31.0 0.0 5.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO00681.1 - 5e-30 101.8 29.5 3.5e-09 35.8 1.8 4.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO00681.1 - 2.1e-29 100.9 26.0 1.1e-14 53.7 3.8 3.8 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 ETO00681.1 - 2.9e-25 86.0 16.2 9.4e-08 31.4 0.5 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO00681.1 - 2.2e-21 73.9 30.7 1.6e-07 30.5 2.3 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETO00681.1 - 3.1e-13 48.7 14.9 0.0003 20.7 1.3 5.6 3 2 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO00681.1 - 1.7e-09 38.1 0.1 0.0045 17.6 0.1 3.2 2 2 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO00681.1 - 4e-09 36.2 0.0 0.22 12.2 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO00681.1 - 5.8e-09 35.8 2.9 0.11 12.9 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat PPR PF01535.15 ETO00681.1 - 4.6e-06 26.2 7.0 0.085 12.8 0.2 4.3 4 0 0 4 4 4 2 PPR repeat Apc3 PF12895.2 ETO00681.1 - 5.6e-06 26.4 10.3 0.0004 20.4 2.6 2.8 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.1 ETO00681.1 - 1.5e-05 24.2 8.7 0.0051 16.0 0.6 2.9 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP RPN7 PF10602.4 ETO00681.1 - 2.1e-05 23.9 10.0 0.051 12.9 0.1 3.9 1 1 3 4 4 4 2 26S proteasome subunit RPN7 TPR_19 PF14559.1 ETO00681.1 - 2.2e-05 24.6 0.4 0.0053 17.0 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Sel1 PF08238.7 ETO00681.1 - 2.9e-05 24.5 10.3 0.84 10.3 0.1 4.6 4 0 0 4 4 4 2 Sel1 repeat TPR_3 PF07720.7 ETO00681.1 - 3e-05 23.6 18.1 0.15 11.9 0.4 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF627 PF04781.7 ETO00681.1 - 0.00079 19.0 1.8 1.8 8.1 0.1 3.2 1 1 2 3 3 3 1 Protein of unknown function (DUF627) SHNi-TPR PF10516.4 ETO00681.1 - 0.0013 17.9 1.0 5 6.4 0.0 4.0 4 0 0 4 4 4 0 SHNi-TPR Pep3_Vps18 PF05131.9 ETO00681.1 - 0.0014 18.0 1.0 1.5 8.2 0.0 3.7 3 1 1 4 4 4 1 Pep3/Vps18/deep orange family DUF357 PF04010.8 ETO00681.1 - 0.018 14.7 7.6 0.22 11.2 0.3 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF357) MIT PF04212.13 ETO00681.1 - 0.037 13.9 13.9 3.1 7.7 0.3 4.1 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_9 PF13371.1 ETO00681.1 - 0.048 13.5 0.0 7.3 6.5 0.0 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat GBP_C PF02841.9 ETO00681.1 - 0.077 12.1 0.1 2.2 7.4 0.0 2.7 3 0 0 3 3 3 0 Guanylate-binding protein, C-terminal domain WSS_VP PF12175.3 ETO00681.1 - 0.09 11.8 0.1 0.24 10.4 0.0 1.7 1 1 1 2 2 2 0 White spot syndrome virus structural envelope protein VP DUF1268 PF06896.6 ETO00681.1 - 0.16 12.2 0.8 22 5.4 0.2 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF1268) Ubiq-assoc PF09145.5 ETO00681.1 - 0.27 11.1 20.2 4.3 7.2 0.3 5.4 3 3 3 6 6 6 0 Ubiquitin-associated PPR_2 PF13041.1 ETO00681.1 - 1.5 8.8 7.9 1.3 9.0 0.1 3.3 4 0 0 4 4 4 0 PPR repeat family FATC PF02260.15 ETO00681.1 - 1.6 8.2 6.6 2.3 7.7 0.1 3.3 4 0 0 4 4 4 0 FATC domain YopX PF09643.5 ETO00681.1 - 2.2 8.2 8.8 2e+02 1.9 6.1 2.9 1 1 0 1 1 1 0 YopX protein Fis1_TPR_C PF14853.1 ETO00681.1 - 3.9 7.4 10.1 51 3.8 0.1 4.0 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat DUF3450 PF11932.3 ETO00681.1 - 8.4 5.5 10.2 7.5 5.7 0.3 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) Nucleoplasmin PF03066.10 ETO00683.1 - 0.3 10.5 10.0 0.75 9.3 4.8 2.2 2 0 0 2 2 2 0 Nucleoplasmin RNase_H2_suC PF08615.6 ETO00683.1 - 5.2 6.9 10.2 11 5.9 7.0 1.7 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) IBB PF01749.15 ETO00684.1 - 0.00017 21.6 4.4 0.00017 21.6 3.0 2.2 2 1 0 2 2 2 1 Importin beta binding domain Arm PF00514.18 ETO00684.1 - 0.021 14.6 0.4 9.2 6.2 0.0 3.1 2 1 0 2 2 2 0 Armadillo/beta-catenin-like repeat INCENP_ARK-bind PF03941.10 ETO00684.1 - 0.099 12.5 0.4 0.26 11.1 0.3 1.8 1 1 0 1 1 1 0 Inner centromere protein, ARK binding region Paramecium_SA PF01508.11 ETO00684.1 - 0.21 11.8 7.7 0.44 10.7 5.3 1.5 1 0 0 1 1 1 0 Paramecium surface antigen domain Arm PF00514.18 ETO00685.1 - 6.6e-10 38.4 0.1 0.0022 17.7 0.0 4.3 4 0 0 4 4 4 4 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 ETO00685.1 - 0.028 14.9 0.0 15 6.2 0.0 2.6 3 0 0 3 3 3 0 HEAT-like repeat Copine PF07002.11 ETO00686.1 - 2.5e-07 30.5 0.1 5.1e-07 29.5 0.0 1.5 2 0 0 2 2 2 1 Copine PPR_2 PF13041.1 ETO00687.1 - 0.0017 18.2 0.1 0.0045 16.9 0.1 1.7 1 0 0 1 1 1 1 PPR repeat family PPR PF01535.15 ETO00687.1 - 0.007 16.2 0.9 0.015 15.2 0.0 2.0 3 0 0 3 3 3 1 PPR repeat PPR_1 PF12854.2 ETO00687.1 - 0.13 11.8 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 PPR repeat DUF1762 PF08574.5 ETO00689.1 - 1.2 9.5 7.1 11 6.4 4.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1762) DUF678 PF05077.7 ETO00690.1 - 0.52 10.3 2.9 0.82 9.7 1.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF678) DUF1886 PF09171.5 ETO00691.1 - 0.07 12.1 0.1 0.095 11.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1886) WD40 PF00400.27 ETO00692.1 - 1.1e-27 94.8 9.0 4.6e-13 48.5 0.3 4.4 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO00692.1 - 9.7e-06 23.9 0.2 0.41 8.7 0.0 3.0 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO00692.1 - 0.0037 16.0 1.0 0.0057 15.4 0.7 1.3 1 0 0 1 1 1 1 Nup133 N terminal like WD40 PF00400.27 ETO00694.1 - 3.9e-71 232.5 12.6 5.9e-12 44.9 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO00694.1 - 2.2e-09 37.2 1.2 0.0061 16.2 0.0 3.6 1 1 4 5 5 5 4 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 ETO00694.1 - 6.5e-07 28.4 3.6 1.1 7.9 0.0 4.6 1 1 2 3 3 3 3 Nup133 N terminal like Nup160 PF11715.3 ETO00694.1 - 1.2e-06 27.0 2.6 0.11 10.6 0.0 4.0 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Nbas_N PF15492.1 ETO00694.1 - 0.00082 18.5 0.7 0.13 11.2 0.0 3.5 1 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Ricin_B_lectin PF00652.17 ETO00694.1 - 0.0016 18.4 4.0 0.0027 17.7 1.2 2.3 2 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain PD40 PF07676.7 ETO00694.1 - 0.0021 17.6 5.8 2.6 7.7 0.0 4.9 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO00694.1 - 0.025 12.9 0.2 0.7 8.1 0.0 2.5 1 1 1 3 3 3 0 Cytochrome D1 heme domain DPPIV_N PF00930.16 ETO00694.1 - 0.041 12.4 0.0 6.7 5.1 0.0 3.4 2 2 1 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region TPR_12 PF13424.1 ETO00695.1 - 3.9e-34 116.4 7.9 3.4e-23 81.3 1.9 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO00695.1 - 6.1e-24 82.6 20.5 1.3e-09 37.2 1.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO00695.1 - 4.8e-23 79.1 11.9 9.9e-08 31.3 0.2 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO00695.1 - 9.1e-22 75.0 5.5 4.9e-08 32.1 0.1 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO00695.1 - 4.5e-19 67.8 12.1 8.2e-10 38.1 4.3 3.0 2 1 0 2 2 2 2 TPR repeat TPR_10 PF13374.1 ETO00695.1 - 7.4e-19 67.0 0.0 3.6e-05 23.5 0.0 4.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO00695.1 - 7.8e-19 65.9 25.5 2.8e-07 29.8 2.4 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat MIT PF04212.13 ETO00695.1 - 1.9e-08 34.0 9.7 0.0088 15.8 0.3 3.2 3 0 0 3 3 3 3 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 ETO00695.1 - 3.2e-08 33.4 3.5 0.012 16.0 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO00695.1 - 2e-07 31.0 0.0 0.03 14.9 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO00695.1 - 4.4e-07 29.5 8.3 0.0046 17.0 0.0 4.5 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO00695.1 - 5.8e-06 26.8 0.3 0.26 12.0 0.0 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat Sel1 PF08238.7 ETO00695.1 - 7.4e-05 23.2 8.1 0.12 13.0 0.3 3.7 3 1 0 3 3 3 2 Sel1 repeat TPR_3 PF07720.7 ETO00695.1 - 0.00035 20.2 14.5 0.028 14.2 0.5 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO00695.1 - 0.0024 17.0 0.1 8 5.8 0.0 3.2 3 0 0 3 3 3 0 SHNi-TPR SNAP PF14938.1 ETO00695.1 - 0.003 16.7 8.1 0.027 13.6 3.1 2.6 2 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP DUF2225 PF09986.4 ETO00695.1 - 0.0045 16.4 6.0 0.025 14.0 1.6 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) Mob_Pre PF01076.14 ETO00695.1 - 0.011 15.3 1.8 0.011 15.3 1.2 1.7 2 0 0 2 2 2 0 Plasmid recombination enzyme Apc3 PF12895.2 ETO00695.1 - 0.015 15.4 9.3 0.28 11.3 5.2 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO00695.1 - 0.02 15.2 1.4 6 7.2 0.0 2.7 2 1 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.15 ETO00695.1 - 0.043 13.7 5.8 0.68 10.0 0.1 3.5 3 0 0 3 3 3 0 PPR repeat TPR_9 PF13371.1 ETO00695.1 - 0.088 12.6 0.0 17 5.3 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat RHD PF00554.17 ETO00695.1 - 0.1 12.3 0.1 6.7 6.4 0.0 2.6 1 1 2 3 3 3 0 Rel homology domain (RHD) DUF3453 PF11935.3 ETO00695.1 - 0.15 11.4 1.8 22 4.3 0.0 3.0 1 1 0 2 2 2 0 Domain of unknown function (DUF3453) SPO22 PF08631.5 ETO00695.1 - 0.54 9.2 6.5 19 4.2 0.1 3.1 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like NSF PF02071.15 ETO00695.1 - 1.1 10.0 5.5 55 5.0 0.1 3.9 3 0 0 3 3 3 0 Aromatic-di-Alanine (AdAR) repeat Sec5 PF15469.1 ETO00695.1 - 5.8 6.6 10.1 4.8 6.8 0.5 3.1 2 1 1 3 3 3 0 Exocyst complex component Sec5 Baculo_Y142 PF04913.7 ETO00697.1 - 0.0098 14.2 0.1 0.012 14.0 0.0 1.0 1 0 0 1 1 1 1 Baculovirus Y142 protein WD40 PF00400.27 ETO00698.1 - 2.1e-12 46.4 0.4 1.2e-08 34.4 0.0 2.5 2 1 0 2 2 2 2 WD domain, G-beta repeat AAA_17 PF13207.1 ETO00699.1 - 0.00073 20.3 0.3 0.048 14.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETO00699.1 - 0.0011 19.1 0.1 0.0031 17.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETO00699.1 - 0.0017 18.6 4.1 0.0096 16.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain G-alpha PF00503.15 ETO00699.1 - 0.0018 17.0 3.7 0.0026 16.4 2.6 1.4 1 1 0 1 1 1 1 G-protein alpha subunit NACHT PF05729.7 ETO00699.1 - 0.0026 17.4 0.0 0.0051 16.4 0.0 1.5 2 0 0 2 2 1 1 NACHT domain UPF0079 PF02367.12 ETO00699.1 - 0.0029 17.2 0.0 0.0049 16.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 DAP3 PF10236.4 ETO00699.1 - 0.0073 15.2 0.3 0.02 13.8 0.1 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 VirE PF05272.6 ETO00699.1 - 0.011 15.2 0.1 0.021 14.3 0.0 1.5 1 0 0 1 1 1 0 Virulence-associated protein E DUF258 PF03193.11 ETO00699.1 - 0.017 14.3 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 ETO00699.1 - 0.02 13.9 0.0 0.042 12.9 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.17 ETO00699.1 - 0.037 14.2 0.9 0.076 13.1 0.0 1.9 2 1 0 2 2 2 0 RNA helicase Sigma54_activat PF00158.21 ETO00699.1 - 0.038 13.4 0.0 0.063 12.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PRK PF00485.13 ETO00699.1 - 0.04 13.4 1.0 0.068 12.7 0.0 1.8 2 1 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 ETO00699.1 - 0.043 13.6 0.2 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 ETO00699.1 - 0.045 12.6 0.0 0.067 12.0 0.0 1.3 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 ETO00699.1 - 0.059 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain PPV_E1_C PF00519.12 ETO00699.1 - 0.086 11.4 0.4 0.31 9.5 0.0 1.8 1 1 1 2 2 2 0 Papillomavirus helicase ATP_bind_1 PF03029.12 ETO00699.1 - 0.087 12.3 2.0 2 7.8 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 ETO00699.1 - 0.1 12.8 0.1 0.1 12.8 0.0 1.9 1 1 1 2 2 2 0 ABC transporter AAA_5 PF07728.9 ETO00699.1 - 0.12 12.1 0.1 0.41 10.3 0.0 1.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) CPT PF07931.7 ETO00699.1 - 0.14 11.8 0.1 0.3 10.6 0.0 1.6 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.1 ETO00699.1 - 0.15 12.0 0.1 0.32 10.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain ATP-synt_G PF04718.10 ETO00699.1 - 0.23 12.1 1.1 0.37 11.4 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial ATP synthase g subunit Gin PF10764.4 ETO00700.1 - 0.028 14.1 1.2 0.062 13.0 0.1 2.1 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin Pox_G7 PF05503.7 ETO00700.1 - 0.033 12.7 0.6 0.048 12.2 0.4 1.2 1 0 0 1 1 1 0 Poxvirus G7-like zf-LITAF-like PF10601.4 ETO00700.1 - 0.11 12.3 0.0 0.36 10.7 0.0 1.8 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain UBN_AB PF14075.1 ETO00701.1 - 0.00038 20.1 0.4 0.00069 19.3 0.3 1.5 1 1 0 1 1 1 1 Ubinuclein conserved middle domain RhoGEF PF00621.15 ETO00701.1 - 0.098 12.5 1.0 0.69 9.7 0.1 2.1 2 0 0 2 2 2 0 RhoGEF domain DASH_Dad2 PF08654.5 ETO00701.1 - 0.12 12.3 0.6 1.4 8.9 0.0 2.3 2 1 0 2 2 2 0 DASH complex subunit Dad2 YebO PF13974.1 ETO00702.1 - 3.9 7.3 8.9 15 5.4 6.1 2.0 1 1 0 1 1 1 0 YebO-like protein DUF3899 PF13038.1 ETO00705.1 - 0.089 12.9 2.7 0.17 12.0 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Pox_D5 PF03288.11 ETO00705.1 - 4.7 7.5 7.6 21 5.4 1.9 3.1 2 1 0 2 2 2 0 Poxvirus D5 protein-like DUF3245 PF11595.3 ETO00706.1 - 0.0078 16.4 0.9 0.016 15.5 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3245) Orbi_VP4 PF05059.7 ETO00707.1 - 0.0052 14.6 0.5 0.0058 14.4 0.3 1.2 1 0 0 1 1 1 1 Orbivirus VP4 core protein EMP24_GP25L PF01105.19 ETO00708.1 - 3.6e-26 91.9 0.0 4.1e-26 91.8 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MaoC_dehydratas PF01575.14 ETO00709.1 - 8.5e-12 44.5 0.0 1.5e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain RNase_H PF00075.19 ETO00710.1 - 5.4e-07 30.0 0.0 7.2e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 RNase H Prolamin_like PF05617.6 ETO00710.1 - 0.061 13.4 0.2 0.093 12.8 0.1 1.3 1 0 0 1 1 1 0 Prolamin-like PUB PF09409.5 ETO00711.1 - 0.00046 19.8 1.6 0.0034 17.1 0.4 2.5 2 1 0 2 2 2 1 PUB domain GlutR_dimer PF00745.15 ETO00711.1 - 0.085 12.8 0.1 0.66 9.9 0.0 2.2 2 1 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF4116 PF13475.1 ETO00711.1 - 0.11 11.9 1.0 2.2 7.8 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4116) SusD-like_3 PF14322.1 ETO00711.1 - 0.98 9.4 4.6 1.5 8.8 0.3 2.1 2 0 0 2 2 2 0 Starch-binding associating with outer membrane Kelch_1 PF01344.20 ETO00713.1 - 2.6e-07 30.0 0.6 2.6e-07 30.0 0.4 1.6 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO00713.1 - 9.6e-05 22.4 0.1 0.00025 21.1 0.0 1.7 1 1 1 2 2 2 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO00713.1 - 0.00015 21.4 0.1 0.00051 19.7 0.0 1.9 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO00713.1 - 0.015 15.4 0.5 0.053 13.7 0.2 2.0 1 1 0 2 2 2 0 Kelch motif Kelch_2 PF07646.10 ETO00713.1 - 0.025 14.3 0.1 0.047 13.4 0.1 1.4 1 0 0 1 1 1 0 Kelch motif ABC_tran PF00005.22 ETO00714.1 - 3.5e-19 69.4 11.1 2.4e-18 66.7 5.3 2.9 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 ETO00714.1 - 8.5e-08 32.4 9.2 8.5e-08 32.4 6.4 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 ETO00714.1 - 7.9e-06 25.3 1.9 0.0003 20.2 0.0 3.0 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_10 PF12846.2 ETO00714.1 - 6.4e-05 22.5 0.3 0.0001 21.8 0.2 1.5 1 1 0 1 1 1 1 AAA-like domain DUF258 PF03193.11 ETO00714.1 - 0.00028 20.0 0.0 0.00055 19.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 ETO00714.1 - 0.00076 18.7 9.7 0.078 12.2 3.0 2.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.12 ETO00714.1 - 0.0013 18.6 0.1 0.0013 18.6 0.1 3.1 2 1 1 3 3 3 1 Domain of unknown function DUF87 AAA_22 PF13401.1 ETO00714.1 - 0.0026 17.9 0.7 0.029 14.4 0.0 2.7 4 0 0 4 4 3 1 AAA domain FtsK_SpoIIIE PF01580.13 ETO00714.1 - 0.0031 17.0 0.0 0.0052 16.2 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family NACHT PF05729.7 ETO00714.1 - 0.0046 16.6 0.1 0.012 15.2 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 ETO00714.1 - 0.0052 17.5 0.1 0.014 16.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETO00714.1 - 0.0056 16.9 1.3 0.025 14.9 0.1 2.7 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 ETO00714.1 - 0.01 15.7 0.1 0.033 14.1 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.1 ETO00714.1 - 0.012 15.0 0.0 0.032 13.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 ETO00714.1 - 0.02 14.4 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 ETO00714.1 - 0.04 13.0 0.0 0.11 11.5 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.17 ETO00714.1 - 0.06 13.5 3.3 1.7 8.8 0.0 3.2 3 0 0 3 3 3 0 RNA helicase Miro PF08477.8 ETO00714.1 - 0.065 13.7 0.0 0.18 12.3 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein AAA_16 PF13191.1 ETO00714.1 - 0.12 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.10 ETO00714.1 - 0.46 10.3 8.5 0.79 9.5 4.7 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 ETO00715.1 - 1.6e-16 60.8 18.0 2.8e-16 60.0 8.3 3.2 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 ETO00715.1 - 2e-06 27.9 12.5 2e-06 27.9 8.6 3.3 2 1 1 3 3 3 1 AAA domain AAA_10 PF12846.2 ETO00715.1 - 0.0001 21.8 0.0 0.00016 21.2 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain AAA_29 PF13555.1 ETO00715.1 - 0.00012 21.4 0.1 0.00053 19.4 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 ETO00715.1 - 0.0005 19.2 0.0 0.00099 18.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 DUF87 PF01935.12 ETO00715.1 - 0.0023 17.8 0.1 0.0023 17.8 0.1 3.0 2 1 0 3 3 3 1 Domain of unknown function DUF87 AAA_17 PF13207.1 ETO00715.1 - 0.0046 17.7 0.0 0.026 15.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETO00715.1 - 0.0048 17.1 4.8 0.055 13.7 0.1 3.6 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETO00715.1 - 0.0051 16.9 0.2 0.056 13.5 0.0 2.7 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 ETO00715.1 - 0.0061 16.0 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family NACHT PF05729.7 ETO00715.1 - 0.0086 15.7 0.1 0.022 14.4 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.1 ETO00715.1 - 0.014 14.8 0.1 0.049 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 ETO00715.1 - 0.034 13.7 0.0 0.074 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 ETO00715.1 - 0.057 12.6 15.0 0.22 10.6 3.1 3.1 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain SR-25 PF10500.4 ETO00715.1 - 0.23 10.8 2.8 0.57 9.6 2.0 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ABC_membrane_2 PF06472.10 ETO00716.1 - 8.5e-09 34.9 4.9 1.2e-08 34.4 3.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 DUF29 PF01724.11 ETO00717.1 - 0.018 14.8 2.2 0.035 13.9 1.5 1.6 1 1 0 1 1 1 0 Domain of unknown function DUF29 DUF1910 PF08928.5 ETO00717.1 - 0.97 9.4 8.7 0.18 11.8 2.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) cNMP_binding PF00027.24 ETO00718.1 - 3.3e-09 36.4 0.0 5.4e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain NUC194 PF08163.7 ETO00718.1 - 0.019 13.8 4.4 0.022 13.6 3.0 1.1 1 0 0 1 1 1 0 NUC194 domain Nop25 PF09805.4 ETO00718.1 - 0.29 11.2 6.4 0.37 10.8 4.4 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Secretin_N_2 PF07655.8 ETO00718.1 - 0.37 11.2 16.5 0.6 10.5 11.4 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain WD40 PF00400.27 ETO00719.1 - 4.1e-11 42.3 2.3 7e-09 35.2 0.0 3.6 3 1 1 4 4 4 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO00719.1 - 0.018 13.1 0.0 0.018 13.1 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DUF3807 PF12720.2 ETO00721.1 - 2.2 8.4 9.0 2.4 8.3 6.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Peptidase_C14 PF00656.17 ETO00722.1 - 9.3e-09 35.3 0.2 2.2e-08 34.1 0.1 1.5 1 1 0 1 1 1 1 Caspase domain CDC45 PF02724.9 ETO00723.1 - 0.0051 14.9 1.9 0.0045 15.0 1.3 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF908 PF06012.7 ETO00723.1 - 0.049 12.9 6.9 0.074 12.3 4.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Tim54 PF11711.3 ETO00723.1 - 0.052 12.1 1.7 0.062 11.8 1.2 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2894 PF11445.3 ETO00723.1 - 0.052 13.8 4.2 0.072 13.3 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) DUF2201_N PF13203.1 ETO00723.1 - 0.091 11.9 4.9 0.11 11.5 3.4 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF789 PF05623.7 ETO00723.1 - 0.12 11.7 4.4 0.18 11.2 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF789) Raftlin PF15250.1 ETO00723.1 - 0.14 10.6 9.0 0.18 10.3 6.2 1.1 1 0 0 1 1 1 0 Raftlin Menin PF05053.8 ETO00723.1 - 0.2 9.7 10.4 0.23 9.5 7.2 1.1 1 0 0 1 1 1 0 Menin Ndc1_Nup PF09531.5 ETO00723.1 - 0.2 10.0 7.9 0.22 9.9 5.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Neur_chan_memb PF02932.11 ETO00723.1 - 0.22 11.4 2.2 0.25 11.1 1.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Mem_trans PF03547.13 ETO00723.1 - 0.23 9.7 3.8 0.27 9.5 2.6 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF3807 PF12720.2 ETO00723.1 - 0.28 11.3 10.1 0.38 10.9 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Rtf2 PF04641.7 ETO00723.1 - 0.28 10.3 9.3 0.37 9.9 6.5 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Afi1 PF07792.7 ETO00723.1 - 0.31 11.0 13.8 0.5 10.3 9.6 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CobT PF06213.7 ETO00723.1 - 0.44 9.6 9.9 0.23 10.5 5.6 1.4 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DUF1510 PF07423.6 ETO00723.1 - 0.49 9.7 16.9 0.68 9.2 11.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Macoilin PF09726.4 ETO00723.1 - 0.59 8.3 13.1 0.78 7.9 9.0 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF702 PF05142.7 ETO00723.1 - 0.68 10.0 7.5 1 9.5 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Sporozoite_P67 PF05642.6 ETO00723.1 - 0.76 7.5 10.2 0.88 7.3 7.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AUX_IAA PF02309.11 ETO00723.1 - 1 9.0 8.8 1.4 8.5 6.1 1.2 1 0 0 1 1 1 0 AUX/IAA family DUF1675 PF07897.6 ETO00723.1 - 1.2 8.9 13.1 1.6 8.5 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Hid1 PF12722.2 ETO00723.1 - 1.8 6.1 19.5 2.1 5.8 13.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.12 ETO00723.1 - 2.2 7.0 8.8 2.6 6.7 6.1 1.1 1 0 0 1 1 1 0 Presenilin SPX PF03105.14 ETO00723.1 - 4.5 6.9 24.1 10 5.8 15.6 1.8 1 1 1 2 2 2 0 SPX domain RP-C_C PF11800.3 ETO00723.1 - 4.7 6.8 7.5 6.5 6.3 5.2 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region GET2 PF08690.5 ETO00723.1 - 5.7 6.0 12.9 8.6 5.5 8.9 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 DUF4661 PF15576.1 ETO00723.1 - 7.8 6.0 5.8 11 5.6 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) WD40 PF00400.27 ETO00724.1 - 8e-24 82.6 16.1 5.4e-11 41.9 0.8 4.2 3 1 1 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO00724.1 - 8.5e-06 24.1 0.8 0.0002 19.6 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO00724.1 - 0.045 12.4 1.4 0.086 11.5 0.2 1.8 1 1 1 2 2 2 0 Nup133 N terminal like DOG1 PF14144.1 ETO00725.1 - 0.28 11.2 1.9 6.7 6.8 0.2 2.2 1 1 1 2 2 2 0 Seed dormancy control Flavi_NS1 PF00948.16 ETO00725.1 - 0.29 9.4 6.8 0.33 9.3 4.7 1.0 1 0 0 1 1 1 0 Flavivirus non-structural Protein NS1 Asp_Glu_race_2 PF14669.1 ETO00725.1 - 0.32 10.2 4.9 0.36 10.0 3.4 1.0 1 0 0 1 1 1 0 Putative aspartate racemase DUF2344 PF10105.4 ETO00725.1 - 0.57 9.6 9.2 0.72 9.3 6.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) Ecotin PF03974.8 ETO00725.1 - 0.58 9.8 7.0 0.81 9.4 4.8 1.3 1 0 0 1 1 1 0 Ecotin DUF2458 PF10454.4 ETO00725.1 - 0.6 9.9 21.4 1.7 8.5 14.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2458) Prominin PF05478.6 ETO00725.1 - 1.1 6.7 14.4 1.1 6.7 10.0 1.0 1 0 0 1 1 1 0 Prominin Mitofilin PF09731.4 ETO00725.1 - 1.1 7.8 23.4 2.5 6.6 16.2 1.5 1 1 0 1 1 1 0 Mitochondrial inner membrane protein Striatin PF08232.7 ETO00725.1 - 1.2 9.4 16.2 2 8.7 10.9 1.6 1 1 0 1 1 1 0 Striatin family ArgK PF03308.11 ETO00725.1 - 1.9 7.1 5.1 2.4 6.8 3.5 1.2 1 0 0 1 1 1 0 ArgK protein DUF359 PF04019.7 ETO00725.1 - 2.5 7.4 5.3 1 8.7 0.7 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF359) RE_Alw26IDE PF09665.5 ETO00725.1 - 2.8 6.5 15.9 3.2 6.3 11.0 1.0 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) Adenylsucc_synt PF00709.16 ETO00725.1 - 3.2 6.3 8.0 3.7 6.0 5.5 1.2 1 0 0 1 1 1 0 Adenylosuccinate synthetase Ax_dynein_light PF10211.4 ETO00725.1 - 5.2 6.8 29.5 5 6.9 4.7 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain tRNA-synt_1g PF09334.6 ETO00725.1 - 6.1 5.3 14.3 1.3 7.5 4.6 1.9 1 1 1 2 2 2 0 tRNA synthetases class I (M) Pex19 PF04614.7 ETO00726.1 - 0.0081 15.7 3.2 0.01 15.4 2.2 1.1 1 0 0 1 1 1 1 Pex19 protein family Lipoprotein_7 PF01540.11 ETO00726.1 - 0.013 14.6 6.2 0.015 14.4 4.3 1.2 1 0 0 1 1 1 0 Adhesin lipoprotein Prominin PF05478.6 ETO00726.1 - 0.016 12.7 1.9 0.019 12.5 1.3 1.2 1 0 0 1 1 1 0 Prominin TACC PF05010.9 ETO00726.1 - 0.031 14.0 3.6 0.035 13.8 2.5 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) DUF948 PF06103.6 ETO00726.1 - 0.031 14.1 0.8 0.074 12.9 0.5 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Uds1 PF15456.1 ETO00726.1 - 0.075 13.0 2.7 0.13 12.2 1.9 1.4 1 0 0 1 1 1 0 Up-regulated During Septation Hormone_1 PF00103.15 ETO00726.1 - 0.081 12.2 1.0 0.13 11.6 0.7 1.3 1 0 0 1 1 1 0 Somatotropin hormone family GBP_C PF02841.9 ETO00726.1 - 0.1 11.8 5.7 0.14 11.3 3.9 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Blo-t-5 PF11642.3 ETO00726.1 - 0.19 11.5 7.5 0.42 10.3 5.2 1.7 1 1 0 1 1 1 0 Mite allergen Blo t 5 Seryl_tRNA_N PF02403.17 ETO00726.1 - 0.19 11.7 10.7 0.34 10.9 7.4 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF904 PF06005.7 ETO00726.1 - 0.28 11.5 8.4 0.59 10.4 5.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Hemagglutinin PF00509.13 ETO00726.1 - 0.46 8.5 5.1 0.67 8.0 3.5 1.1 1 0 0 1 1 1 0 Haemagglutinin DUF3782 PF12644.2 ETO00726.1 - 0.55 10.0 3.2 1.4 8.7 2.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) UPF0122 PF04297.9 ETO00726.1 - 1 9.4 8.2 1.5 8.9 4.9 1.8 1 1 1 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like bZIP_1 PF00170.16 ETO00726.1 - 6.3 6.8 10.7 2.8 7.9 2.4 2.7 2 1 1 3 3 3 0 bZIP transcription factor WD40 PF00400.27 ETO00727.1 - 3.6e-63 207.3 26.3 2e-11 43.3 0.4 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO00727.1 - 7.1e-13 47.5 3.5 0.00076 17.7 0.1 5.0 2 1 3 5 5 5 5 Nucleoporin Nup120/160 DUF1900 PF08954.6 ETO00727.1 - 3.1e-05 23.5 0.5 2.5 7.6 0.0 4.6 3 1 1 5 5 5 2 Domain of unknown function (DUF1900) Methyltransf_25 PF13649.1 ETO00727.1 - 0.0052 17.1 0.1 19 5.7 0.0 3.9 3 2 0 3 3 3 2 Methyltransferase domain Transglut_prok PF09017.5 ETO00728.1 - 0.23 10.5 2.5 0.26 10.3 1.7 1.1 1 0 0 1 1 1 0 Microbial transglutaminase IncA PF04156.9 ETO00728.1 - 1.7 8.1 9.6 4.5 6.8 6.7 1.6 1 1 0 1 1 1 0 IncA protein zf-C3HC4_2 PF13923.1 ETO00729.1 - 0.016 15.2 2.9 0.016 15.2 2.0 2.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Terpene_synth_C PF03936.11 ETO00729.1 - 0.083 12.1 0.3 0.12 11.5 0.2 1.2 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain eIF3_N PF09440.5 ETO00730.1 - 0.042 14.0 0.0 0.084 13.0 0.0 1.5 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain zf-TRAF PF02176.13 ETO00731.1 - 0.00018 21.8 1.4 0.00018 21.8 1.0 2.4 3 0 0 3 3 3 1 TRAF-type zinc finger zf-RING_2 PF13639.1 ETO00731.1 - 0.023 14.5 1.1 0.23 11.2 0.3 2.8 2 1 0 2 2 2 0 Ring finger domain PUB PF09409.5 ETO00733.1 - 0.0039 16.9 0.5 0.011 15.4 0.4 1.8 1 0 0 1 1 1 1 PUB domain CW_binding_1 PF01473.15 ETO00733.1 - 0.79 9.9 5.4 0.66 10.2 1.5 2.6 2 0 0 2 2 2 0 Putative cell wall binding repeat MMR_HSR1 PF01926.18 ETO00734.1 - 2.2e-05 24.3 2.2 9.9e-05 22.2 0.3 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 ETO00734.1 - 2.7e-05 23.4 0.3 0.00032 19.9 0.2 2.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 ETO00734.1 - 0.0022 18.2 0.1 0.0022 18.2 0.1 2.3 2 1 0 2 2 2 1 ABC transporter Miro PF08477.8 ETO00734.1 - 0.0036 17.7 1.0 0.017 15.5 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein T2SE PF00437.15 ETO00734.1 - 0.011 14.6 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 ETO00734.1 - 0.013 15.0 0.1 0.032 13.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.18 ETO00734.1 - 0.02 14.6 5.7 1.3 8.8 0.0 3.4 2 1 1 3 3 3 0 Dynamin family AAA_28 PF13521.1 ETO00734.1 - 0.022 14.7 0.7 0.057 13.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 ETO00734.1 - 0.034 13.5 0.1 0.069 12.5 0.1 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_25 PF13481.1 ETO00734.1 - 0.039 13.3 0.1 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 ETO00734.1 - 0.047 13.8 0.7 0.42 10.7 0.1 2.6 3 0 0 3 3 3 0 AAA domain DUF771 PF05595.6 ETO00735.1 - 0.11 12.3 2.1 1.5 8.7 0.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF771) Clenterotox PF03505.9 ETO00736.1 - 0.042 13.2 3.2 0.05 12.9 2.2 1.1 1 0 0 1 1 1 0 Clostridium enterotoxin Leu_Phe_trans PF03588.9 ETO00736.1 - 0.045 12.9 1.1 0.08 12.0 0.7 1.6 1 1 0 1 1 1 0 Leucyl/phenylalanyl-tRNA protein transferase LysM PF01476.15 ETO00736.1 - 0.091 12.6 0.1 5.3 7.0 0.0 2.5 1 1 1 2 2 2 0 LysM domain CG-1 PF03859.11 ETO00736.1 - 0.17 11.4 3.7 0.24 10.9 2.5 1.5 1 1 0 1 1 1 0 CG-1 domain RNA_pol_Rpb1_5 PF04998.12 ETO00736.1 - 3.5 6.8 5.1 3.9 6.6 3.6 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF3244 PF11589.3 ETO00737.1 - 0.058 13.0 0.7 0.077 12.7 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3244) Cofilin_ADF PF00241.15 ETO00737.1 - 0.24 11.2 2.8 0.35 10.7 1.8 1.5 1 1 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein WD40 PF00400.27 ETO00738.1 - 3.7e-70 229.4 25.2 3.5e-12 45.7 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO00738.1 - 1e-10 41.6 0.8 0.00066 19.4 0.0 3.8 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO00738.1 - 9.9e-10 37.1 13.5 0.0098 14.0 0.2 5.4 2 2 3 5 5 5 5 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO00738.1 - 8e-06 24.3 1.4 0.12 10.6 0.1 3.2 1 1 1 3 3 3 3 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 ETO00738.1 - 3.8e-05 22.8 3.5 1.1 8.6 0.1 5.5 6 0 0 6 6 6 1 Proteasome subunit A N-terminal signature DUF1258 PF06869.7 ETO00738.1 - 0.00012 21.2 0.5 0.015 14.4 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1258) PQQ_2 PF13360.1 ETO00738.1 - 0.00027 20.4 2.7 0.22 10.9 0.0 3.1 2 1 0 2 2 2 1 PQQ-like domain DUF3601 PF12208.3 ETO00738.1 - 0.0011 18.7 0.0 0.59 10.0 0.0 3.7 2 2 2 4 4 4 1 Domain of unknown function (DUF3601) PD40 PF07676.7 ETO00738.1 - 0.0013 18.3 7.9 2.6 7.8 0.0 5.7 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.9 ETO00738.1 - 0.0014 17.5 0.7 0.51 9.0 0.0 2.8 1 1 1 3 3 3 2 Coatomer WD associated region Nucleoporin_N PF08801.6 ETO00738.1 - 0.0066 15.2 6.9 3.3 6.3 0.3 4.3 1 1 1 4 4 4 2 Nup133 N terminal like Hira PF07569.6 ETO00738.1 - 0.042 13.0 0.0 0.32 10.1 0.0 2.4 2 1 1 3 3 3 0 TUP1-like enhancer of split Phage_GP20 PF06810.6 ETO00740.1 - 0.00068 19.1 8.9 0.00068 19.1 6.2 1.9 1 1 1 2 2 2 1 Phage minor structural protein GP20 DUF641 PF04859.7 ETO00740.1 - 0.046 13.4 9.5 0.22 11.2 3.2 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) IncA PF04156.9 ETO00740.1 - 0.064 12.8 13.4 0.073 12.6 9.3 1.1 1 0 0 1 1 1 0 IncA protein DUF2730 PF10805.3 ETO00740.1 - 0.072 12.8 1.3 0.089 12.5 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) OsmC PF02566.14 ETO00740.1 - 0.19 11.9 0.6 0.31 11.2 0.4 1.3 1 0 0 1 1 1 0 OsmC-like protein Golgin_A5 PF09787.4 ETO00740.1 - 0.48 8.8 11.2 0.58 8.6 7.8 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 Spc7 PF08317.6 ETO00740.1 - 0.6 8.7 15.4 0.64 8.6 10.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Kinetocho_Slk19 PF12709.2 ETO00740.1 - 0.64 10.1 12.4 0.63 10.1 5.0 2.3 1 1 1 2 2 2 0 Central kinetochore-associated DUF3074 PF11274.3 ETO00740.1 - 2 8.0 5.2 2.2 7.8 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3074) MSV199 PF10553.4 ETO00740.1 - 2.2 8.1 13.7 2.4 8.0 9.5 1.1 1 0 0 1 1 1 0 MSV199 domain PolyA_pol PF01743.15 ETO00740.1 - 3.7 7.7 5.2 3.4 7.9 0.1 2.0 1 1 1 2 2 2 0 Poly A polymerase head domain Activator-TraM PF11657.3 ETO00741.1 - 0.027 13.9 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 Transcriptional activator TraM SUD-M PF11633.3 ETO00741.1 - 0.038 13.2 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 Single-stranded poly(A) binding domain Kelch_2 PF07646.10 ETO00742.1 - 0.00018 21.1 0.4 0.27 11.0 0.1 2.7 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.1 ETO00742.1 - 0.00036 20.5 1.2 0.065 13.4 0.2 2.7 1 1 1 2 2 2 2 Kelch motif Kelch_1 PF01344.20 ETO00742.1 - 0.0056 16.2 1.0 1.8 8.1 0.1 2.6 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 ETO00742.1 - 0.0077 15.9 0.2 1.9 8.3 0.0 2.7 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO00742.1 - 0.092 12.9 0.0 0.62 10.2 0.0 2.3 3 0 0 3 3 3 0 Galactose oxidase, central domain DUF2724 PF10893.3 ETO00742.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) DUF2431 PF10354.4 ETO00744.1 - 0.1 12.5 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) Mcp5_PH PF12814.2 ETO00745.1 - 0.0013 18.6 2.9 0.0031 17.4 0.0 2.1 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology Pox_Rif PF03340.8 ETO00745.1 - 0.0021 16.2 1.0 0.0028 15.8 0.4 1.4 1 1 0 1 1 1 1 Poxvirus rifampicin resistance protein PUB PF09409.5 ETO00746.1 - 0.012 15.3 1.2 0.047 13.4 0.9 2.0 1 1 0 1 1 1 0 PUB domain Kinesin PF00225.18 ETO00748.1 - 1.4e-29 102.9 2.6 1.8e-29 102.4 1.8 1.1 1 0 0 1 1 1 1 Kinesin motor domain DUF972 PF06156.8 ETO00748.1 - 0.02 15.2 1.4 0.02 15.2 1.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Baculo_IE-1 PF05290.6 ETO00748.1 - 0.095 12.4 2.2 0.48 10.1 0.4 2.2 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) ABC2_membrane_3 PF12698.2 ETO00748.1 - 0.18 10.8 0.7 0.22 10.5 0.5 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Mnd1 PF03962.10 ETO00750.1 - 0.086 12.4 14.3 0.14 11.8 9.9 1.3 1 0 0 1 1 1 0 Mnd1 family Spc7 PF08317.6 ETO00750.1 - 0.21 10.2 13.7 0.27 9.8 9.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Afi1 PF07792.7 ETO00750.1 - 0.43 10.5 5.5 0.9 9.5 3.8 1.5 1 1 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Cob_adeno_trans PF01923.13 ETO00750.1 - 0.7 9.6 3.7 0.65 9.7 1.7 1.5 1 1 1 2 2 2 0 Cobalamin adenosyltransferase IncA PF04156.9 ETO00750.1 - 0.72 9.4 11.0 1.1 8.8 7.6 1.3 1 0 0 1 1 1 0 IncA protein ATG16 PF08614.6 ETO00750.1 - 0.77 9.5 17.9 0.19 11.5 8.1 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.2 ETO00750.1 - 1.6 8.5 17.9 2.4 7.9 11.4 1.8 1 1 0 1 1 1 0 Tropomyosin like DUF342 PF03961.8 ETO00750.1 - 2.2 6.5 8.7 2.9 6.1 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Uds1 PF15456.1 ETO00750.1 - 2.6 8.0 12.2 4.4 7.3 7.5 2.1 1 1 1 2 2 2 0 Up-regulated During Septation SlyX PF04102.7 ETO00750.1 - 2.8 8.3 11.6 3.5 8.0 4.3 2.4 2 1 0 2 2 2 0 SlyX Syntaxin-6_N PF09177.6 ETO00750.1 - 2.8 8.3 7.0 6.9 7.1 4.4 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF1664 PF07889.7 ETO00750.1 - 6.9 6.4 8.5 1.7 8.4 1.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF3552 PF12072.3 ETO00750.1 - 7.6 5.6 15.6 10 5.2 10.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) MspA PF09203.6 ETO00751.1 - 0.016 14.6 0.1 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 MspA MYT1 PF08474.6 ETO00751.1 - 0.07 12.6 0.8 0.08 12.4 0.5 1.2 1 1 0 1 1 1 0 Myelin transcription factor 1 DUF2945 PF11160.3 ETO00751.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2945) DUF4652 PF15525.1 ETO00752.1 - 0.08 12.3 10.6 0.09 12.1 7.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) PBP1_TM PF14812.1 ETO00752.1 - 0.22 11.8 2.0 0.24 11.7 1.4 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FimP PF09766.4 ETO00752.1 - 0.23 10.4 6.1 0.24 10.4 4.2 1.1 1 0 0 1 1 1 0 Fms-interacting protein DUF912 PF06024.7 ETO00752.1 - 0.26 11.3 9.1 0.3 11.1 6.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ETRAMP PF09716.5 ETO00752.1 - 0.29 11.1 4.7 0.36 10.8 3.3 1.3 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) HSP90 PF00183.13 ETO00752.1 - 2.1 6.6 7.1 2.4 6.4 4.9 1.0 1 0 0 1 1 1 0 Hsp90 protein Secretin_N_2 PF07655.8 ETO00752.1 - 2.4 8.6 11.2 2.8 8.3 7.7 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain YqfQ PF14181.1 ETO00752.1 - 5.3 7.0 8.4 5.9 6.9 5.8 1.1 1 0 0 1 1 1 0 YqfQ-like protein Fibrinogen_BP PF08017.6 ETO00753.1 - 0.0051 15.0 0.1 0.0059 14.8 0.1 1.1 1 0 0 1 1 1 1 Fibrinogen binding protein DUF3456 PF11938.3 ETO00753.1 - 0.12 12.3 2.0 0.17 11.8 1.4 1.2 1 0 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP Polysacc_synt_4 PF04669.8 ETO00754.1 - 0.047 13.0 0.7 0.059 12.7 0.4 1.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis DUF3206 PF11472.3 ETO00754.1 - 0.11 12.3 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3206) DUF603 PF04645.7 ETO00754.1 - 0.46 10.3 3.8 0.22 11.4 0.7 1.6 1 1 1 2 2 2 0 Protein of unknown function, DUF603 XRN_N PF03159.13 ETO00755.1 - 1.6e-12 47.3 0.1 1.6e-12 47.3 0.1 2.3 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus DUF1183 PF06682.7 ETO00755.1 - 0.016 14.8 1.6 0.018 14.6 1.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) FLO_LFY PF01698.11 ETO00755.1 - 0.018 13.9 6.1 0.021 13.6 4.3 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Menin PF05053.8 ETO00755.1 - 0.18 9.9 4.6 0.18 9.9 3.2 1.2 1 0 0 1 1 1 0 Menin Nop14 PF04147.7 ETO00755.1 - 0.19 9.5 15.3 0.2 9.5 10.6 1.1 1 0 0 1 1 1 0 Nop14-like family Herpes_PAP PF03325.8 ETO00755.1 - 0.26 10.8 7.1 0.3 10.5 4.9 1.1 1 0 0 1 1 1 0 Herpesvirus polymerase accessory protein DUF2201_N PF13203.1 ETO00755.1 - 1.8 7.6 9.5 2.3 7.3 6.6 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Neur_chan_memb PF02932.11 ETO00755.1 - 2.4 7.9 6.8 2.7 7.8 4.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.2 ETO00755.1 - 6.9 4.2 10.2 8.3 3.9 7.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RP-C_C PF11800.3 ETO00755.1 - 9.4 5.8 8.0 14 5.3 5.5 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region XRN_N PF03159.13 ETO00756.1 - 1.9e-12 47.1 0.1 1.9e-12 47.1 0.1 2.4 2 1 0 2 2 1 1 XRN 5'-3' exonuclease N-terminus RNase_H2-Ydr279 PF09468.5 ETO00756.1 - 0.0019 17.4 7.9 0.0019 17.4 5.5 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Nop14 PF04147.7 ETO00756.1 - 0.0035 15.3 19.5 0.0041 15.1 13.5 1.1 1 0 0 1 1 1 1 Nop14-like family DUF1183 PF06682.7 ETO00756.1 - 0.02 14.4 2.4 0.024 14.2 1.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) FLO_LFY PF01698.11 ETO00756.1 - 0.048 12.5 9.2 0.064 12.0 6.4 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein SprA-related PF12118.3 ETO00756.1 - 0.083 12.2 14.1 0.097 11.9 9.7 1.1 1 0 0 1 1 1 0 SprA-related family GAGA_bind PF06217.7 ETO00756.1 - 0.15 12.0 10.9 0.17 11.8 7.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Herpes_DNAp_acc PF04929.7 ETO00756.1 - 0.15 10.9 9.0 0.18 10.6 6.2 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Rtf2 PF04641.7 ETO00756.1 - 0.16 11.1 13.8 0.21 10.7 9.5 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger CENP-T PF15511.1 ETO00756.1 - 0.17 11.0 10.2 0.19 10.9 7.1 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Hid1 PF12722.2 ETO00756.1 - 0.4 8.3 13.8 0.47 8.0 9.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1510 PF07423.6 ETO00756.1 - 0.54 9.5 21.2 0.68 9.2 14.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2201_N PF13203.1 ETO00756.1 - 0.58 9.2 12.1 0.73 8.9 8.4 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain eIF-3c_N PF05470.7 ETO00756.1 - 0.76 7.7 16.4 0.83 7.6 11.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus GPCR_chapero_1 PF11904.3 ETO00756.1 - 0.8 8.7 12.2 0.98 8.4 8.4 1.2 1 0 0 1 1 1 0 GPCR-chaperone Zip PF02535.17 ETO00756.1 - 1 8.2 4.8 1.1 8.2 3.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Herpes_env PF01673.13 ETO00756.1 - 1.4 7.3 6.5 1.7 7.1 4.5 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein DDHD PF02862.12 ETO00756.1 - 1.4 8.6 9.1 2 8.1 6.3 1.3 1 0 0 1 1 1 0 DDHD domain Neur_chan_memb PF02932.11 ETO00756.1 - 1.9 8.3 8.3 2.2 8.0 5.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Apt1 PF10351.4 ETO00756.1 - 2.6 6.8 16.3 3.3 6.4 11.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Raftlin PF15250.1 ETO00756.1 - 4.1 5.8 11.7 4.7 5.6 8.1 1.1 1 0 0 1 1 1 0 Raftlin Daxx PF03344.10 ETO00756.1 - 4.6 5.5 21.1 5.1 5.4 14.6 1.0 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 ETO00756.1 - 7.5 4.4 29.6 3.9 5.4 19.1 1.4 1 1 0 1 1 1 0 CDC45-like protein ETRAMP PF09716.5 ETO00756.1 - 8.8 6.3 8.5 15 5.6 5.3 1.8 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) MDFI PF15316.1 ETO00756.1 - 9.7 6.1 7.5 14 5.6 5.2 1.1 1 0 0 1 1 1 0 MyoD family inhibitor zf-TRAF PF02176.13 ETO00757.1 - 1.1e-06 28.8 3.1 1.1e-06 28.8 2.1 2.0 2 1 0 2 2 2 1 TRAF-type zinc finger DUF1644 PF07800.7 ETO00757.1 - 0.024 14.4 4.4 0.12 12.2 3.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) zf-BED PF02892.10 ETO00757.1 - 0.51 10.1 4.3 4 7.2 0.0 3.3 4 0 0 4 4 4 0 BED zinc finger zf-C3HC4_2 PF13923.1 ETO00757.1 - 2.2 8.3 9.1 0.43 10.6 0.7 3.4 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Toxin_1 PF00087.16 ETO00757.1 - 7.9 6.9 9.6 25 5.3 0.2 3.1 2 2 0 2 2 2 0 Snake toxin Fer4_3 PF12798.2 ETO00757.1 - 9.4 7.0 6.6 7.1 7.4 2.3 2.6 2 1 0 2 2 2 0 4Fe-4S binding domain TPR_12 PF13424.1 ETO00759.1 - 4.3e-20 71.4 3.8 2.6e-17 62.5 0.4 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO00759.1 - 6.8e-14 50.7 12.2 1e-05 24.8 0.1 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO00759.1 - 6e-13 47.5 4.9 2.2e-08 33.2 0.0 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO00759.1 - 3.4e-12 45.2 15.0 2e-06 27.1 0.6 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO00759.1 - 4.7e-12 45.3 3.6 5.6e-09 35.5 0.4 2.1 2 0 0 2 2 2 2 TPR repeat TPR_10 PF13374.1 ETO00759.1 - 9.7e-12 44.4 0.0 1.8e-05 24.5 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO00759.1 - 9.3e-11 40.8 7.9 0.0038 17.0 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO00759.1 - 1.7e-08 33.9 4.8 0.00033 20.6 0.1 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO00759.1 - 8.4e-06 26.3 0.0 0.27 11.9 0.0 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO00759.1 - 0.00029 21.1 0.2 0.16 12.5 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO00759.1 - 0.0037 17.3 3.8 0.74 9.9 0.2 2.2 1 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 ETO00759.1 - 0.069 13.8 0.0 22 6.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.7 ETO00759.1 - 0.15 11.9 5.6 2.3 8.1 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.7 ETO00759.1 - 0.45 11.2 4.4 6.1 7.6 0.4 3.1 3 0 0 3 3 3 0 Sel1 repeat YscK PF06578.7 ETO00760.1 - 0.07 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 YOP proteins translocation protein K (YscK) FlaF PF07309.6 ETO00760.1 - 0.079 12.8 0.1 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Flagellar protein FlaF Pox_H7 PF04787.7 ETO00762.1 - 0.28 10.9 4.5 0.18 11.6 0.2 2.6 3 0 0 3 3 3 0 Late protein H7 Chitin_bind_4 PF00379.18 ETO00763.1 - 0.098 12.9 0.2 0.22 11.7 0.1 1.6 1 0 0 1 1 1 0 Insect cuticle protein LHH PF14411.1 ETO00764.1 - 0.0015 18.6 0.7 0.0019 18.3 0.5 1.1 1 0 0 1 1 1 1 A nuclease of the HNH/ENDO VII superfamily with conserved LHH zf-MIZ PF02891.15 ETO00764.1 - 0.12 11.9 1.0 0.19 11.2 0.7 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger RNA_pol_Rpc4 PF05132.9 ETO00764.1 - 0.62 10.0 3.6 0.8 9.6 2.5 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Nucleoporin_C PF03177.9 ETO00765.1 - 0.0097 14.4 3.6 0.011 14.2 2.5 1.0 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal His_Phos_2 PF00328.17 ETO00765.1 - 0.088 12.1 1.5 0.09 12.0 1.0 1.1 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Laminin_II PF06009.7 ETO00765.1 - 0.14 11.8 1.5 0.15 11.8 1.0 1.2 1 0 0 1 1 1 0 Laminin Domain II DUF1963 PF09234.5 ETO00765.1 - 0.22 11.7 3.3 0.25 11.5 2.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1963) Peptidase_S46 PF10459.4 ETO00765.1 - 0.29 9.4 2.6 0.34 9.2 1.8 1.0 1 0 0 1 1 1 0 Peptidase S46 MSG PF02349.10 ETO00765.1 - 0.4 10.7 11.6 0.57 10.1 8.0 1.4 1 0 0 1 1 1 0 Major surface glycoprotein AATF-Che1 PF13339.1 ETO00765.1 - 0.42 10.7 4.4 0.61 10.2 3.1 1.3 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor OmpH PF03938.9 ETO00765.1 - 0.5 10.2 4.4 0.57 10.1 3.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) IncA PF04156.9 ETO00765.1 - 0.57 9.7 8.6 0.72 9.4 6.0 1.2 1 0 0 1 1 1 0 IncA protein DNA_topoisoIV PF00521.15 ETO00765.1 - 2.5 6.8 8.5 2.6 6.8 5.9 1.0 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A DUF815 PF05673.8 ETO00767.1 - 0.0031 16.4 0.0 0.0066 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 ETO00767.1 - 0.0044 17.3 0.1 0.0044 17.3 0.1 2.2 2 1 0 2 2 2 1 ABC transporter Sigma54_activ_2 PF14532.1 ETO00767.1 - 0.013 15.5 0.1 0.12 12.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain PduV-EutP PF10662.4 ETO00767.1 - 0.013 14.9 0.2 0.033 13.6 0.1 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 ETO00767.1 - 0.032 13.4 0.0 0.094 11.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 ETO00767.1 - 0.042 13.8 0.3 0.21 11.5 0.0 2.2 2 1 1 3 3 3 0 AAA ATPase domain AAA_22 PF13401.1 ETO00767.1 - 0.051 13.7 3.3 0.17 12.0 0.1 3.0 2 1 1 3 3 3 0 AAA domain FANCI_S3 PF14677.1 ETO00767.1 - 0.053 12.9 11.1 0.057 12.8 5.6 2.1 2 1 0 2 2 2 0 FANCI solenoid 3 Arch_ATPase PF01637.13 ETO00767.1 - 0.074 12.7 0.1 0.074 12.7 0.1 3.2 1 1 3 4 4 4 0 Archaeal ATPase Sigma54_activat PF00158.21 ETO00767.1 - 0.081 12.3 0.0 0.27 10.6 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.9 ETO00767.1 - 0.12 12.0 0.2 0.56 9.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Miro PF08477.8 ETO00767.1 - 0.57 10.6 4.5 1.2 9.6 0.1 2.6 2 1 0 2 2 2 0 Miro-like protein AAA PF00004.24 ETO00767.1 - 2 8.5 5.3 0.54 10.4 0.1 2.6 3 2 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Lumazine_bd PF12870.2 ETO00770.1 - 7.8 6.5 10.3 12 6.0 2.6 2.6 1 1 2 3 3 3 0 Lumazine-binding domain GlcNAc PF11397.3 ETO00772.1 - 3.3e-16 59.3 0.0 3.8e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) PBP_GOBP PF01395.17 ETO00773.1 - 0.024 14.2 1.2 5.8 6.5 0.1 2.3 1 1 1 2 2 2 0 PBP/GOBP family CENP-B_N PF04218.8 ETO00773.1 - 0.39 10.1 2.5 9.4 5.7 0.0 3.0 3 1 0 3 3 3 0 CENP-B N-terminal DNA-binding domain MRL1 PF13003.2 ETO00774.1 - 0.19 11.5 3.1 0.27 11.0 2.1 1.3 1 1 0 1 1 1 0 Ribosomal protein L1 DUF3671 PF12420.3 ETO00775.1 - 1.2e-05 25.2 3.6 1.3e-05 25.1 2.5 1.2 1 0 0 1 1 1 1 Protein of unknown function AIF_C PF14721.1 ETO00775.1 - 0.033 14.4 2.2 0.045 13.9 1.5 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF912 PF06024.7 ETO00775.1 - 0.1 12.6 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TruD PF01142.13 ETO00775.1 - 0.13 10.8 2.6 0.15 10.7 1.8 1.0 1 0 0 1 1 1 0 tRNA pseudouridine synthase D (TruD) DUF3464 PF11947.3 ETO00775.1 - 0.13 11.6 2.2 0.19 11.2 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF694 PF05107.7 ETO00775.1 - 0.2 10.8 3.4 0.26 10.4 2.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF694) DUF3899 PF13038.1 ETO00775.1 - 0.49 10.5 4.8 0.77 9.9 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) DUF106 PF01956.11 ETO00775.1 - 0.77 9.2 3.1 0.7 9.4 2.2 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 OAD_gamma PF04277.8 ETO00775.1 - 2 8.8 4.9 2.6 8.4 3.4 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Peptidase_S49_N PF08496.5 ETO00775.1 - 2.6 7.8 12.4 3.8 7.2 8.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal AAA_11 PF13086.1 ETO00775.1 - 3.5 7.1 5.0 81 2.6 4.7 1.9 2 0 0 2 2 2 0 AAA domain BLVR PF06375.6 ETO00775.1 - 4 7.2 18.5 6.4 6.5 12.8 1.4 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) SR-25 PF10500.4 ETO00775.1 - 4.8 6.5 21.4 6.8 6.0 14.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2625 PF10946.3 ETO00776.1 - 0.025 13.4 0.0 0.054 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF2625 DUF4503 PF14951.1 ETO00776.1 - 0.029 12.5 0.1 0.037 12.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) APG6 PF04111.7 ETO00776.1 - 0.26 10.2 25.2 0.19 10.7 6.2 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF812 PF05667.6 ETO00776.1 - 4.3 5.7 19.1 0.032 12.7 5.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF812) AAA_23 PF13476.1 ETO00776.1 - 4.5 7.5 13.4 8.3 6.6 9.3 1.6 1 1 0 1 1 1 0 AAA domain DUF4164 PF13747.1 ETO00776.1 - 7.2 6.8 13.5 0.62 10.2 4.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) SecA_DEAD PF07517.9 ETO00776.1 - 7.9 5.6 8.4 0.61 9.3 1.9 1.8 2 0 0 2 2 2 0 SecA DEAD-like domain DUF972 PF06156.8 ETO00776.1 - 8.2 6.8 18.1 11 6.3 5.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) AAA_11 PF13086.1 ETO00777.1 - 0.02 14.4 4.7 0.026 14.0 3.3 1.1 1 0 0 1 1 1 0 AAA domain FLO_LFY PF01698.11 ETO00777.1 - 0.13 11.0 9.5 0.16 10.7 6.6 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein SMN PF06003.7 ETO00777.1 - 0.25 10.4 7.7 0.36 9.8 5.3 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DUF1168 PF06658.7 ETO00777.1 - 0.61 9.5 30.2 0.85 9.1 21.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Hom_end_hint PF05203.11 ETO00777.1 - 1.5 8.4 7.5 2 8.0 5.2 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint SR-25 PF10500.4 ETO00777.1 - 1.7 8.1 27.3 2.2 7.6 18.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CDC27 PF09507.5 ETO00777.1 - 2.5 7.2 21.7 2.8 7.0 15.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF3513 PF12026.3 ETO00777.1 - 8.2 5.9 10.5 11 5.5 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) GAGA_bind PF06217.7 ETO00777.1 - 8.3 6.2 19.0 10 6.0 13.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Peptidase_S49_N PF08496.5 ETO00777.1 - 8.8 6.1 17.8 15 5.3 12.4 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RVT_1 PF00078.22 ETO00778.1 - 2.7e-12 46.5 0.2 7.8e-12 45.0 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) XhlA PF10779.4 ETO00778.1 - 2.5 8.1 6.8 41 4.1 4.7 2.5 1 1 0 1 1 1 0 Haemolysin XhlA DUF948 PF06103.6 ETO00779.1 - 0.19 11.6 1.4 0.33 10.8 1.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) zf-RING_2 PF13639.1 ETO00780.1 - 0.002 17.8 2.8 0.0063 16.3 1.9 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO00780.1 - 0.0054 16.7 2.5 0.037 14.0 1.7 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1644 PF07800.7 ETO00780.1 - 8.2 6.2 12.3 49 3.7 8.5 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) zf-C3HC4_2 PF13923.1 ETO00783.1 - 0.0003 20.7 2.4 0.0027 17.6 1.7 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Tet_JBP PF12851.2 ETO00783.1 - 0.011 15.0 1.3 0.013 14.8 0.9 1.1 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily Cys_knot PF00007.17 ETO00783.1 - 0.045 13.8 5.9 0.057 13.5 4.1 1.2 1 0 0 1 1 1 0 Cystine-knot domain Phage_Gp23 PF10669.4 ETO00783.1 - 0.13 12.3 0.1 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DUF1644 PF07800.7 ETO00783.1 - 0.18 11.6 8.7 0.046 13.5 3.9 1.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1644) Amino_oxidase PF01593.19 ETO00784.1 - 5.8e-15 55.3 0.0 9.7e-12 44.6 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DNA_pol_viral_N PF00242.12 ETO00784.1 - 0.17 10.8 8.4 0.24 10.3 5.8 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Macoilin PF09726.4 ETO00784.1 - 0.19 9.9 8.1 0.23 9.7 5.6 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF2146 PF10220.4 ETO00784.1 - 0.32 8.9 3.6 0.39 8.6 2.5 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) RR_TM4-6 PF06459.7 ETO00784.1 - 2.5 7.8 8.5 3.5 7.4 5.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Serinc PF03348.10 ETO00784.1 - 2.6 6.6 5.8 3.5 6.2 4.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) RNA_polI_A34 PF08208.6 ETO00784.1 - 3.7 7.1 11.1 5.1 6.7 7.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 NPR3 PF03666.8 ETO00784.1 - 8.5 4.7 9.0 11 4.3 6.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FKBP_C PF00254.23 ETO00787.1 - 1.8e-08 34.2 0.3 2.4e-08 33.8 0.2 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase MRC1 PF09444.5 ETO00787.1 - 0.0049 17.1 9.0 0.0049 17.1 6.2 1.7 2 0 0 2 2 2 1 MRC1-like domain Cwf_Cwc_15 PF04889.7 ETO00787.1 - 0.0049 16.6 7.6 0.0085 15.8 5.3 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein FYDLN_acid PF09538.5 ETO00787.1 - 0.21 12.1 18.1 0.039 14.5 9.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Pox_Ag35 PF03286.9 ETO00787.1 - 0.68 9.4 18.1 0.051 13.0 9.3 1.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein hNIFK_binding PF12196.3 ETO00787.1 - 4.5 6.7 7.0 16 4.9 4.8 2.0 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK DUF1510 PF07423.6 ETO00787.1 - 7 5.9 15.4 0.81 9.0 7.9 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF2457 PF10446.4 ETO00787.1 - 9.3 4.8 20.2 15 4.1 14.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) EF-hand_7 PF13499.1 ETO00788.1 - 0.0026 17.8 0.0 0.008 16.2 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO00788.1 - 0.0041 16.3 0.1 0.03 13.6 0.0 2.4 2 1 1 3 3 3 1 EF hand Merozoite_SPAM PF07133.6 ETO00788.1 - 0.055 13.3 16.1 0.12 12.2 11.1 1.5 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) EF-hand_6 PF13405.1 ETO00788.1 - 0.1 12.5 0.1 0.37 10.7 0.1 1.9 1 1 0 1 1 1 0 EF-hand domain Zip PF02535.17 ETO00788.1 - 0.28 10.1 1.0 0.43 9.5 0.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter EF-hand_5 PF13202.1 ETO00788.1 - 0.29 10.5 2.3 4.4 6.8 0.0 3.0 3 0 0 3 3 3 0 EF hand RR_TM4-6 PF06459.7 ETO00788.1 - 4.5 7.0 16.8 0.5 10.2 7.9 1.9 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 ETO00788.1 - 4.5 6.9 8.9 0.38 10.5 1.8 2.1 2 0 0 2 2 2 0 DDHD domain Cas_Csy4 PF09618.5 ETO00788.1 - 8.3 6.1 7.9 5.6 6.7 2.3 2.2 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy4) CENP-B_dimeris PF09026.5 ETO00789.1 - 0.023 14.9 1.3 0.047 13.9 0.9 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2578 PF10843.3 ETO00789.1 - 0.12 11.9 5.0 0.15 11.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2578) DEP PF00610.16 ETO00791.1 - 2.4e-08 33.5 2.8 3.7e-08 32.9 0.0 2.5 2 1 1 3 3 3 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF3439 PF11921.3 ETO00793.1 - 0.0088 15.7 2.5 0.02 14.6 1.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 ETO00793.1 - 0.014 13.2 1.8 0.021 12.6 1.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.6 ETO00793.1 - 1.3 6.9 9.3 2.1 6.2 6.4 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Menin PF05053.8 ETO00794.1 - 0.12 10.4 5.2 0.11 10.7 3.6 1.1 1 0 0 1 1 1 0 Menin Dicty_REP PF05086.7 ETO00794.1 - 0.31 8.7 14.1 0.33 8.6 9.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 ETO00794.1 - 0.56 9.9 22.7 0.96 9.2 15.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein CUE PF02845.11 ETO00795.1 - 0.00013 21.3 0.4 0.051 13.0 0.1 2.7 2 1 0 2 2 2 2 CUE domain TFIID_90kDa PF04494.10 ETO00795.1 - 0.019 15.0 0.5 0.034 14.2 0.4 1.4 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit DUF2140 PF09911.4 ETO00795.1 - 0.029 13.5 1.9 0.14 11.2 1.3 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF3654 PF12376.3 ETO00795.1 - 0.035 13.9 0.6 0.064 13.0 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3654) HlyU PF10115.4 ETO00795.1 - 0.11 12.2 0.2 1.4 8.8 0.1 2.2 1 1 1 2 2 2 0 Transcriptional activator HlyU PfUIS3 PF11567.3 ETO00795.1 - 0.18 11.9 3.8 0.1 12.7 0.6 1.9 2 0 0 2 2 2 0 Plasmodium falciparum UIS3 membrane protein HBS1_N PF08938.5 ETO00795.1 - 0.18 11.9 1.2 0.53 10.4 0.2 2.2 2 0 0 2 2 2 0 HBS1 N-terminus PilO PF04350.8 ETO00795.1 - 0.27 11.1 2.3 12 5.7 0.8 2.2 1 1 1 2 2 2 0 Pilus assembly protein, PilO Sec2p PF06428.6 ETO00795.1 - 1.6 8.6 5.9 1.6 8.6 3.1 1.9 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF4534 PF15049.1 ETO00798.1 - 0.14 11.7 1.4 0.18 11.3 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4534) Cys_rich_VLP PF14194.1 ETO00799.1 - 0.037 13.7 0.2 0.07 12.8 0.1 1.4 1 0 0 1 1 1 0 Cysteine-rich VLP Vps35 PF03635.12 ETO00801.1 - 0.012 13.7 2.7 0.014 13.5 1.9 1.0 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 Lipoprotein_3 PF00938.12 ETO00801.1 - 0.025 14.3 1.0 0.044 13.5 0.7 1.4 1 0 0 1 1 1 0 Lipoprotein DUF3713 PF12506.3 ETO00801.1 - 5.3 7.1 9.4 10 6.2 4.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3713) Kelch_1 PF01344.20 ETO00803.1 - 2e-08 33.6 0.4 3.4e-07 29.6 0.2 2.1 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.1 ETO00803.1 - 2.7e-07 30.2 0.4 1e-05 25.1 0.1 2.4 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO00803.1 - 4.5e-07 29.7 0.7 4.2e-05 23.5 0.2 2.2 1 1 1 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO00803.1 - 9.2e-06 25.6 0.1 0.00011 22.2 0.0 2.3 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO00803.1 - 3.2e-05 23.7 0.7 0.0055 16.6 0.3 2.2 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.10 ETO00803.1 - 5.4e-05 22.7 0.2 0.00061 19.4 0.1 2.1 2 0 0 2 2 2 1 Kelch motif DUF131 PF01998.12 ETO00804.1 - 0.091 12.1 0.3 0.19 11.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF131 Virul_fac_BrkB PF03631.10 ETO00804.1 - 0.1 11.9 0.8 0.15 11.3 0.6 1.2 1 0 0 1 1 1 0 Virulence factor BrkB ART PF01129.13 ETO00805.1 - 0.0042 16.2 0.0 0.006 15.7 0.0 1.3 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase DUF3713 PF12506.3 ETO00805.1 - 0.38 10.8 3.8 4.8 7.2 2.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3713) HSCB_C PF07743.8 ETO00806.1 - 0.097 13.1 0.2 0.18 12.2 0.1 1.4 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain Ank_4 PF13637.1 ETO00807.1 - 2.3e-08 34.3 0.4 2.2e-07 31.1 0.2 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO00807.1 - 3.6e-08 32.8 0.3 0.0043 17.1 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 ETO00807.1 - 1.8e-07 31.4 0.5 9.8e-07 29.0 0.3 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO00807.1 - 7.8e-07 29.1 0.2 0.0046 17.1 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 ETO00807.1 - 1.6e-05 24.4 0.2 0.094 12.5 0.0 2.8 3 1 0 3 3 3 2 Ankyrin repeat DNA_topoisoIV PF00521.15 ETO00807.1 - 0.0029 16.5 3.2 0.0032 16.3 2.2 1.0 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_pol_E_B PF04042.11 ETO00807.1 - 0.012 14.8 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B PaaSYMP PF14738.1 ETO00807.1 - 0.16 11.6 3.9 0.23 11.2 2.7 1.2 1 0 0 1 1 1 0 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 NACHT PF05729.7 ETO00808.1 - 1.5e-06 27.9 0.1 4.5e-06 26.4 0.1 1.7 1 1 0 1 1 1 1 NACHT domain DUF3722 PF12519.3 ETO00808.1 - 0.0016 17.7 0.1 0.002 17.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) PfUIS3 PF11567.3 ETO00808.1 - 0.086 12.9 2.8 0.12 12.5 0.9 1.8 1 1 1 2 2 2 0 Plasmodium falciparum UIS3 membrane protein DUF1863 PF08937.6 ETO00808.1 - 0.21 11.6 1.8 0.3 11.1 0.5 1.7 1 1 1 2 2 2 0 MTH538 TIR-like domain (DUF1863) PPR_2 PF13041.1 ETO00809.1 - 1.4e-08 34.6 4.0 1.7e-05 24.6 0.5 2.8 1 1 1 2 2 2 2 PPR repeat family PPR PF01535.15 ETO00809.1 - 1e-07 31.4 0.9 0.0046 16.8 0.0 3.0 2 0 0 2 2 2 2 PPR repeat PPR_3 PF13812.1 ETO00809.1 - 0.00047 20.2 0.0 2.1 8.8 0.0 2.9 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 ETO00809.1 - 0.0046 16.3 0.4 0.043 13.2 0.0 2.3 2 0 0 2 2 2 1 PPR repeat SRP19 PF01922.12 ETO00809.1 - 0.088 13.4 0.1 0.33 11.5 0.0 2.0 2 0 0 2 2 2 0 SRP19 protein WD40 PF00400.27 ETO00811.1 - 3.2e-08 33.1 0.7 0.00029 20.6 0.1 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO00811.1 - 0.00029 19.1 0.0 0.00042 18.5 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Kelch_4 PF13418.1 ETO00812.1 - 8.6e-07 28.6 0.3 0.88 9.3 0.0 4.7 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO00812.1 - 8.8e-07 28.3 4.1 0.0016 17.9 0.1 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO00812.1 - 0.00014 21.5 1.1 0.57 10.0 0.1 4.4 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 ETO00812.1 - 0.0044 16.9 4.9 1.4 8.9 0.0 4.4 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.1 ETO00812.1 - 0.015 15.4 0.0 1.5 9.0 0.0 3.3 3 0 0 3 3 3 0 Galactose oxidase, central domain WD40 PF00400.27 ETO00814.1 - 1.3e-12 47.1 2.2 7.8e-12 44.6 0.9 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO00814.1 - 2.6e-05 22.5 0.2 2.7e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Siah-Interact_N PF09032.6 ETO00814.1 - 0.024 14.6 2.3 0.038 14.0 1.6 1.3 1 0 0 1 1 1 0 Siah interacting protein, N terminal TerB-C PF15615.1 ETO00814.1 - 0.031 14.5 0.2 0.042 14.0 0.2 1.1 1 0 0 1 1 1 0 TerB-C domain IFP_35_N PF07334.8 ETO00814.1 - 0.034 14.1 1.5 0.054 13.4 1.0 1.5 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Spc7 PF08317.6 ETO00814.1 - 0.041 12.5 5.2 0.051 12.2 3.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Folliculin PF11704.3 ETO00814.1 - 0.097 12.2 1.6 0.11 12.0 1.1 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF4164 PF13747.1 ETO00814.1 - 0.1 12.7 0.8 0.14 12.2 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) CENP-H PF05837.7 ETO00814.1 - 0.11 12.7 3.9 0.17 12.0 2.7 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF972 PF06156.8 ETO00814.1 - 0.45 10.8 4.0 0.63 10.4 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) SH3_8 PF13457.1 ETO00814.1 - 0.88 9.7 4.8 0.97 9.6 2.2 2.0 2 1 0 2 2 2 0 SH3-like domain DivIC PF04977.10 ETO00814.1 - 2.1 7.8 6.7 3.2 7.2 4.7 1.4 1 0 0 1 1 1 0 Septum formation initiator ERM PF00769.14 ETO00814.1 - 2.5 7.5 10.9 3.4 7.1 7.5 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family zf-RING_2 PF13639.1 ETO00815.1 - 0.0013 18.4 1.1 0.0013 18.4 0.8 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO00815.1 - 0.0046 16.9 0.5 0.0046 16.9 0.4 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) YjcZ PF13990.1 ETO00815.1 - 0.0068 15.5 5.4 0.0099 15.0 3.7 1.3 1 0 0 1 1 1 1 YjcZ-like protein HR1 PF02185.11 ETO00815.1 - 0.18 11.5 22.3 0.49 10.1 2.1 3.3 1 1 1 2 2 2 0 Hr1 repeat Phasin PF05597.6 ETO00815.1 - 0.24 11.1 12.2 0.3 10.8 4.5 2.5 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF3810 PF12725.2 ETO00815.1 - 1.1 8.1 5.5 2.1 7.1 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) BPL_N PF09825.4 ETO00815.1 - 1.1 7.9 7.6 1.6 7.4 5.3 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Med4 PF10018.4 ETO00815.1 - 2.9 7.2 10.5 6.4 6.1 7.3 1.6 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Pox_A_type_inc PF04508.7 ETO00815.1 - 6.2 6.8 6.6 16 5.6 0.1 3.8 3 1 1 4 4 4 0 Viral A-type inclusion protein repeat Synaptobrevin PF00957.16 ETO00815.1 - 7.3 6.2 12.2 0.51 9.9 2.5 2.6 2 1 1 3 3 3 0 Synaptobrevin DUF1644 PF07800.7 ETO00815.1 - 9 6.1 19.8 0.23 11.2 7.2 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1644) DUF3685 PF12452.3 ETO00816.1 - 0.14 11.3 0.9 3.3 6.8 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3685) SCRL PF06876.7 ETO00817.1 - 5.1 7.1 10.5 25 4.9 0.1 2.6 2 1 0 2 2 2 0 Plant self-incompatibility response (SCRL) protein Ras PF00071.17 ETO00818.1 - 7.4e-18 64.4 2.2 5.2e-17 61.7 1.6 1.9 1 1 0 1 1 1 1 Ras family Miro PF08477.8 ETO00818.1 - 5.4e-13 49.4 0.5 1.1e-12 48.5 0.4 1.4 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO00818.1 - 7.3e-07 28.5 0.2 0.00013 21.3 0.1 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETO00818.1 - 0.00017 21.5 0.2 0.00026 20.9 0.1 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 ETO00818.1 - 0.0013 18.4 0.2 0.0016 18.1 0.1 1.2 1 0 0 1 1 1 1 Archaeal ATPase SRPRB PF09439.5 ETO00818.1 - 0.0016 17.7 0.3 0.039 13.1 0.0 2.0 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 ETO00818.1 - 0.0077 15.3 0.3 0.012 14.7 0.2 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_18 PF13238.1 ETO00818.1 - 0.015 15.6 0.1 0.019 15.2 0.1 1.2 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 ETO00818.1 - 0.038 13.8 1.2 0.066 13.0 0.8 1.5 1 1 0 1 1 1 0 Dynamin family AAA_24 PF13479.1 ETO00818.1 - 0.08 12.5 0.0 0.2 11.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 ETO00818.1 - 0.091 12.4 0.1 0.17 11.5 0.0 1.6 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 ETO00818.1 - 0.13 12.4 0.0 0.17 11.9 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 ETO00818.1 - 3.3 7.9 7.4 4.1 7.6 0.1 2.1 1 1 1 2 2 2 0 AAA domain Abhydrolase_7 PF12715.2 ETO00819.1 - 0.02 13.8 0.4 0.028 13.3 0.3 1.1 1 0 0 1 1 1 0 Abhydrolase family NPCC PF08058.6 ETO00819.1 - 0.24 11.2 1.6 0.26 11.1 0.1 1.7 1 1 1 2 2 2 0 Nuclear pore complex component Abi_2 PF07751.6 ETO00820.1 - 0.0076 16.4 1.0 0.0079 16.4 0.7 1.1 1 0 0 1 1 1 1 Abi-like protein DUF1041 PF06292.12 ETO00820.1 - 0.013 15.6 1.1 0.016 15.3 0.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1041) MinE PF03776.9 ETO00820.1 - 0.064 12.7 1.1 0.43 10.1 0.0 2.1 1 1 1 2 2 2 0 Septum formation topological specificity factor MinE Adenine_glyco PF03352.8 ETO00820.1 - 0.18 11.3 2.0 0.23 10.9 1.4 1.2 1 0 0 1 1 1 0 Methyladenine glycosylase Jnk-SapK_ap_N PF09744.4 ETO00820.1 - 4.1 7.3 11.2 4.3 7.2 7.8 1.0 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 SR-25 PF10500.4 ETO00820.1 - 5.4 6.4 11.8 4.8 6.5 8.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2621 PF11084.3 ETO00821.1 - 0.021 14.5 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) Kelch_1 PF01344.20 ETO00826.1 - 1.7e-07 30.6 2.2 4.2e-05 22.9 0.5 3.6 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 ETO00826.1 - 8.4e-07 28.9 3.8 0.046 13.9 0.5 4.3 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 ETO00826.1 - 1.4e-06 28.1 3.0 0.006 16.5 0.5 4.0 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO00826.1 - 0.00032 20.4 0.9 0.46 10.3 0.2 3.0 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO00826.1 - 0.0021 17.7 8.8 0.029 14.1 0.2 4.9 5 1 0 5 5 5 1 Kelch motif Kelch_3 PF13415.1 ETO00826.1 - 0.015 15.4 1.3 0.086 13.0 0.2 2.8 4 0 0 4 4 4 0 Galactose oxidase, central domain U-box PF04564.10 ETO00827.1 - 1.7e-11 43.9 1.5 7e-11 41.9 0.0 2.6 2 0 0 2 2 2 1 U-box domain DUF948 PF06103.6 ETO00827.1 - 0.03 14.1 4.1 0.1 12.4 0.3 3.0 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) LOH1CR12 PF10158.4 ETO00827.1 - 0.051 13.3 11.0 0.27 11.0 4.2 2.5 1 1 1 2 2 2 0 Tumour suppressor protein SAM_1 PF00536.25 ETO00827.1 - 0.073 13.2 1.8 0.11 12.6 0.0 2.2 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) G-gamma PF00631.17 ETO00827.1 - 0.16 11.7 1.9 2.2 8.0 0.3 2.8 2 0 0 2 2 2 0 GGL domain DUF4473 PF14747.1 ETO00827.1 - 8.4 6.6 14.4 0.29 11.3 1.8 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4473) Ran_BP1 PF00638.13 ETO00831.1 - 5.9e-06 26.3 0.6 8.3e-06 25.8 0.1 1.5 2 0 0 2 2 2 1 RanBP1 domain DUF1980 PF09323.5 ETO00832.1 - 0.00033 20.4 1.4 0.0012 18.5 0.1 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF1980) PIG-P PF08510.7 ETO00832.1 - 0.01 15.4 0.0 0.01 15.4 0.0 3.8 2 1 2 4 4 4 0 PIG-P Neur_chan_memb PF02932.11 ETO00832.1 - 0.053 13.3 8.8 0.15 11.9 1.1 3.3 3 1 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region TRAP_alpha PF03896.11 ETO00832.1 - 0.085 11.8 1.2 0.18 10.7 0.8 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Afaf PF15339.1 ETO00832.1 - 0.21 11.1 7.2 17 4.9 0.2 3.6 4 0 0 4 4 4 0 Acrosome formation-associated factor DUF3377 PF11857.3 ETO00832.1 - 0.75 9.4 4.0 4.4 7.0 0.4 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Sensor PF13796.1 ETO00832.1 - 4.2 6.9 10.0 13 5.3 0.0 3.4 3 0 0 3 3 3 0 Putative sensor Daxx PF03344.10 ETO00832.1 - 4.6 5.5 9.6 6.7 5.0 6.7 1.1 1 0 0 1 1 1 0 Daxx Family UPF0172 PF03665.8 ETO00833.1 - 0.15 11.5 0.6 0.18 11.2 0.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) AAA_27 PF13514.1 ETO00833.1 - 0.45 8.1 3.4 0.51 7.9 2.4 1.0 1 0 0 1 1 1 0 AAA domain NOA36 PF06524.7 ETO00834.1 - 0.0085 15.3 0.1 0.012 14.9 0.1 1.1 1 0 0 1 1 1 1 NOA36 protein Menin PF05053.8 ETO00834.1 - 0.057 11.5 1.1 0.067 11.3 0.6 1.3 1 1 0 1 1 1 0 Menin DUF4352 PF11611.3 ETO00835.1 - 0.012 15.7 1.0 0.018 15.1 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4352) Sua5_yciO_yrdC PF01300.13 ETO00837.1 - 0.057 12.6 0.3 0.078 12.2 0.2 1.2 1 0 0 1 1 1 0 Telomere recombination Cgr1 PF03879.9 ETO00837.1 - 1.8 8.7 16.8 0.93 9.6 6.4 2.3 2 0 0 2 2 2 0 Cgr1 family G-alpha PF00503.15 ETO00838.1 - 2.8e-66 223.8 4.4 2.1e-53 181.4 0.4 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Arf PF00025.16 ETO00838.1 - 1.2e-12 47.3 0.0 2.1e-09 36.8 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 ETO00838.1 - 0.00018 21.9 0.0 0.44 11.0 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 ETO00838.1 - 0.00066 19.6 0.2 0.0045 16.9 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 ETO00838.1 - 0.19 10.8 2.1 0.98 8.5 0.0 2.7 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region G-alpha PF00503.15 ETO00839.1 - 1e-51 175.8 0.2 2e-51 174.9 0.1 1.4 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO00839.1 - 6.8e-07 28.6 0.0 1e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF3732 PF12532.3 ETO00839.1 - 0.017 14.6 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3732) AAA PF00004.24 ETO00841.1 - 0.0006 20.0 0.0 0.0023 18.1 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 ETO00841.1 - 0.0012 17.8 0.0 0.0033 16.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 ETO00841.1 - 0.0023 17.6 0.0 0.0092 15.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 ETO00841.1 - 0.0031 17.8 4.0 0.0084 16.4 0.0 3.4 3 1 0 3 3 3 1 ABC transporter DUF258 PF03193.11 ETO00841.1 - 0.0036 16.4 0.0 0.016 14.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 ETO00841.1 - 0.0069 16.3 0.0 0.28 11.1 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 ETO00841.1 - 0.014 15.5 0.1 0.17 11.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.4 ETO00841.1 - 0.02 14.3 0.5 0.13 11.7 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activ_2 PF14532.1 ETO00841.1 - 0.045 13.7 0.1 0.76 9.8 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain Miro PF08477.8 ETO00841.1 - 0.23 11.9 5.0 3.8 8.0 0.0 4.2 4 0 0 4 4 4 0 Miro-like protein ubiquitin PF00240.18 ETO00842.1 - 6.3e-07 28.6 0.0 1.3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 ETO00842.1 - 0.00088 18.9 0.1 0.0042 16.7 0.0 2.2 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like VWA_2 PF13519.1 ETO00842.1 - 0.016 15.2 0.0 0.024 14.7 0.0 1.5 1 1 0 1 1 1 0 von Willebrand factor type A domain WD40 PF00400.27 ETO00844.1 - 1.7e-11 43.5 2.0 1.7e-11 43.5 1.4 1.8 2 0 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO00844.1 - 7.7e-05 21.0 0.1 8.9e-05 20.8 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 DUF4570 PF15134.1 ETO00844.1 - 0.00011 22.0 4.0 0.00015 21.5 2.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4570) Clusterin PF01093.12 ETO00844.1 - 0.011 14.6 5.7 0.01 14.6 4.0 1.0 1 0 0 1 1 1 0 Clusterin CCDC144C PF14915.1 ETO00844.1 - 0.023 13.6 12.6 0.03 13.2 8.8 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region TMCO5 PF14992.1 ETO00844.1 - 0.054 12.6 12.6 0.067 12.3 8.8 1.1 1 0 0 1 1 1 0 TMCO5 family MSA_2 PF00985.12 ETO00844.1 - 0.12 12.4 3.9 0.18 11.9 2.7 1.4 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family DUF290 PF01060.18 ETO00844.1 - 0.15 12.0 1.7 4.2 7.4 0.3 2.6 2 1 0 2 2 2 0 Transthyretin-like family DUF972 PF06156.8 ETO00844.1 - 0.32 11.3 5.2 0.56 10.5 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF4407 PF14362.1 ETO00844.1 - 0.34 9.8 2.3 0.45 9.4 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ax_dynein_light PF10211.4 ETO00844.1 - 0.55 10.0 12.4 0.057 13.2 5.5 1.6 1 1 1 2 2 2 0 Axonemal dynein light chain IncA PF04156.9 ETO00844.1 - 0.82 9.2 13.9 1.1 8.8 9.6 1.2 1 0 0 1 1 1 0 IncA protein zf-RING_4 PF14570.1 ETO00846.1 - 1.7e-07 30.7 8.1 1.7e-07 30.7 5.6 2.0 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 ETO00846.1 - 1.5e-05 24.5 9.6 1.5e-05 24.5 6.6 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 ETO00846.1 - 3.7e-05 23.4 13.7 3.7e-05 23.4 9.5 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO00846.1 - 0.00014 21.7 12.7 0.00014 21.7 8.8 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO00846.1 - 0.001 18.6 12.0 0.0024 17.5 8.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 ETO00846.1 - 0.13 11.8 8.9 0.29 10.7 6.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 UPF1_Zn_bind PF09416.5 ETO00847.1 - 0.057 13.0 0.7 0.06 12.9 0.5 1.1 1 0 0 1 1 1 0 RNA helicase (UPF2 interacting domain) zf-RING_UBOX PF13445.1 ETO00847.1 - 0.062 13.0 1.0 0.084 12.6 0.7 1.4 1 1 0 1 1 1 0 RING-type zinc-finger WD40 PF00400.27 ETO00848.1 - 5.4e-132 425.5 47.3 1.2e-14 53.5 0.1 11.4 12 0 0 12 12 12 10 WD domain, G-beta repeat Nup160 PF11715.3 ETO00848.1 - 3.1e-13 48.7 18.0 0.0032 15.6 0.2 6.8 1 1 5 6 6 6 5 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO00848.1 - 4.3e-11 41.7 3.5 0.046 12.0 0.0 5.5 1 1 5 6 6 6 4 Cytochrome D1 heme domain BBS2_Mid PF14783.1 ETO00848.1 - 7.9e-10 38.5 5.8 1.9 8.2 0.1 7.9 2 2 6 8 8 8 1 Ciliary BBSome complex subunit 2, middle region DPPIV_N PF00930.16 ETO00848.1 - 1.4e-07 30.4 1.6 0.016 13.8 0.0 5.7 1 1 5 7 7 7 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PQQ_2 PF13360.1 ETO00848.1 - 6.9e-07 28.9 1.5 0.011 15.2 1.1 4.6 1 1 0 1 1 1 1 PQQ-like domain Proteasome_A_N PF10584.4 ETO00848.1 - 1.9e-06 27.0 15.0 4 6.8 0.0 9.5 10 0 0 10 10 10 1 Proteasome subunit A N-terminal signature DUF727 PF05303.7 ETO00848.1 - 5.6e-06 26.0 3.8 0.78 9.5 0.0 6.6 3 3 4 7 7 7 1 Protein of unknown function (DUF727) Reg_prop PF07494.6 ETO00848.1 - 9.5e-06 25.0 2.0 2.7 8.3 0.0 6.9 7 0 0 7 7 6 1 Two component regulator propeller DUF1258 PF06869.7 ETO00848.1 - 1.8e-05 23.9 5.7 0.15 11.1 0.2 4.9 2 2 2 4 4 4 1 Protein of unknown function (DUF1258) DUF4221 PF13970.1 ETO00848.1 - 3e-05 23.5 4.5 0.99 8.6 0.1 4.7 2 2 2 5 5 5 1 Domain of unknown function (DUF4221) PD40 PF07676.7 ETO00848.1 - 3.1e-05 23.5 24.1 3.8 7.2 0.0 9.2 10 0 0 10 10 10 1 WD40-like Beta Propeller Repeat NYD-SP28_assoc PF14775.1 ETO00848.1 - 0.0002 20.9 4.5 56 3.5 0.0 7.8 10 0 0 10 10 10 0 Sperm tail C-terminal domain DUF3601 PF12208.3 ETO00848.1 - 0.00021 21.1 0.0 5.8 6.9 0.0 5.6 4 2 2 7 7 6 0 Domain of unknown function (DUF3601) DUF3312 PF11768.3 ETO00848.1 - 0.00033 19.0 0.6 3.1 5.9 0.0 4.6 4 2 0 4 4 4 1 Protein of unknown function (DUF3312) DUF3892 PF13031.1 ETO00848.1 - 0.00039 20.7 0.8 2 8.8 0.0 5.2 3 2 4 7 7 7 1 Protein of unknown function (DUF3892) Str_synth PF03088.11 ETO00848.1 - 0.00039 20.3 0.4 9.9 6.2 0.0 5.0 3 3 1 4 4 4 0 Strictosidine synthase HARP PF07443.8 ETO00848.1 - 0.00073 18.8 0.0 12 5.3 0.0 4.9 5 0 0 5 5 4 0 HepA-related protein (HARP) DUF4275 PF14101.1 ETO00848.1 - 0.0029 17.6 0.0 7.3 6.6 0.0 4.4 3 1 0 4 4 4 0 Domain of unknown function (DUF4275) DUF3732 PF12532.3 ETO00848.1 - 0.0034 16.9 1.8 3 7.3 0.0 3.9 4 2 0 4 4 4 1 Protein of unknown function (DUF3732) Peptidase_S29 PF02907.10 ETO00848.1 - 0.0048 16.4 1.7 0.67 9.4 0.2 3.2 2 1 1 3 3 3 1 Hepatitis C virus NS3 protease DUF3509 PF12021.3 ETO00848.1 - 0.0081 15.8 0.0 7.1 6.4 0.0 4.0 3 2 2 5 5 5 0 Protein of unknown function (DUF3509) PLD_C PF12357.3 ETO00848.1 - 0.015 14.8 0.1 86 2.7 0.0 5.7 10 1 1 11 11 9 0 Phospholipase D C terminal CPSF_A PF03178.10 ETO00848.1 - 0.039 13.0 1.5 0.91 8.5 0.1 3.5 1 1 2 3 3 3 0 CPSF A subunit region PB1-F2 PF11986.3 ETO00848.1 - 0.066 13.2 0.1 5.7 7.0 0.0 3.7 4 1 0 4 4 3 0 Influenza A Proapoptotic protein SLH PF00395.15 ETO00848.1 - 0.094 12.4 0.0 41 4.0 0.0 3.9 4 1 1 5 5 4 0 S-layer homology domain BMC PF00936.14 ETO00848.1 - 0.19 11.4 0.0 25 4.6 0.0 2.5 2 0 0 2 2 2 0 BMC domain Sod_Fe_N PF00081.17 ETO00849.1 - 0.052 13.7 0.2 0.22 11.8 0.0 1.9 2 0 0 2 2 2 0 Iron/manganese superoxide dismutases, alpha-hairpin domain FlxA PF14282.1 ETO00849.1 - 0.46 10.4 5.3 0.31 10.9 0.1 2.6 2 1 1 3 3 3 0 FlxA-like protein Peptidase_C14 PF00656.17 ETO00851.1 - 2.1e-08 34.1 1.2 3.2e-08 33.5 0.8 1.4 1 1 0 1 1 1 1 Caspase domain C9orf72-like PF15019.1 ETO00851.1 - 0.033 13.4 1.0 0.74 9.0 0.1 2.0 2 0 0 2 2 2 0 C9orf72-like protein family MitMem_reg PF13012.1 ETO00851.1 - 0.066 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function DHC_N1 PF08385.7 ETO00854.1 - 6.1e-05 21.5 4.3 7e-05 21.4 3.0 1.1 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 MecA PF05389.7 ETO00854.1 - 0.0018 17.8 2.5 0.0019 17.7 1.8 1.1 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) DASH_Hsk3 PF08227.6 ETO00854.1 - 0.12 12.6 0.1 0.19 11.9 0.1 1.4 1 1 0 1 1 1 0 DASH complex subunit Hsk3 like DUF2813 PF11398.3 ETO00858.1 - 2.2 7.2 6.8 1.8 7.5 1.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2813) Daxx PF03344.10 ETO00859.1 - 0.011 14.2 7.0 0.015 13.8 4.9 1.1 1 0 0 1 1 1 0 Daxx Family NESP55 PF06390.7 ETO00859.1 - 0.42 9.9 10.3 0.65 9.3 7.1 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) TRAP_alpha PF03896.11 ETO00859.1 - 1.4 7.8 8.1 2.6 6.9 5.6 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Cortexin PF11057.3 ETO00861.1 - 3.1 7.4 6.5 0.67 9.5 1.4 2.2 2 1 0 2 2 2 0 Cortexin of kidney CAAP1 PF15335.1 ETO00862.1 - 0.006 16.7 0.8 0.022 14.9 0.2 2.1 1 1 1 2 2 2 1 Caspase activity and apoptosis inhibitor 1 Condensin2nSMC PF12422.3 ETO00862.1 - 0.17 11.6 1.9 0.48 10.1 1.3 1.6 1 1 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit WD40 PF00400.27 ETO00864.1 - 3.5e-23 80.5 3.8 1.2e-12 47.2 0.2 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO00864.1 - 0.022 12.8 0.1 2 6.4 0.0 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 CitMHS PF03600.11 ETO00865.1 - 3.7e-19 68.5 15.1 4.7e-19 68.1 10.4 1.1 1 0 0 1 1 1 1 Citrate transporter ArsB PF02040.10 ETO00865.1 - 2.4e-11 43.2 11.5 2.9e-11 42.9 8.0 1.1 1 0 0 1 1 1 1 Arsenical pump membrane protein PAS_9 PF13426.1 ETO00866.1 - 0.0088 16.3 0.1 2.5 8.5 0.1 2.6 1 1 1 2 2 2 2 PAS domain LIF_OSM PF01291.12 ETO00867.1 - 0.0019 18.1 1.7 0.0019 18.1 1.2 2.5 2 1 0 2 2 2 1 LIF / OSM family OmpH PF03938.9 ETO00867.1 - 0.0037 17.2 8.7 0.0037 17.2 6.0 3.2 1 1 2 3 3 3 1 Outer membrane protein (OmpH-like) AAA_13 PF13166.1 ETO00867.1 - 0.016 13.6 31.8 0.021 13.3 22.0 1.0 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.4 ETO00867.1 - 0.025 13.5 33.8 0.0092 14.9 9.6 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 FUSC PF04632.7 ETO00867.1 - 0.051 11.9 5.1 0.031 12.7 0.8 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family Filament PF00038.16 ETO00867.1 - 0.09 12.2 33.0 0.12 11.8 22.9 1.1 1 0 0 1 1 1 0 Intermediate filament protein HLH PF00010.21 ETO00867.1 - 2.9 7.6 6.9 4.2 7.1 0.6 3.2 3 0 0 3 3 3 0 Helix-loop-helix DNA-binding domain Mer2 PF09074.5 ETO00867.1 - 3.2 7.6 34.1 0.61 9.9 3.0 3.0 1 1 2 3 3 3 0 Mer2 DUF4404 PF14357.1 ETO00867.1 - 3.8 7.9 27.8 3 8.3 3.3 4.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4404) Peptidase_S49 PF01343.13 ETO00867.1 - 5.6 6.7 9.8 0.74 9.5 3.4 1.9 2 0 0 2 2 2 0 Peptidase family S49 FlxA PF14282.1 ETO00867.1 - 7.2 6.6 31.2 3.8 7.5 8.2 2.8 1 1 1 2 2 2 0 FlxA-like protein zf-RanBP PF00641.13 ETO00868.1 - 4e-06 25.8 8.1 1.1e-05 24.3 5.6 1.8 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Str_synth PF03088.11 ETO00868.1 - 0.088 12.8 0.1 0.22 11.5 0.1 1.7 1 0 0 1 1 1 0 Strictosidine synthase Nop53 PF07767.6 ETO00868.1 - 0.12 11.3 3.8 0.22 10.4 2.7 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Kelch_4 PF13418.1 ETO00870.1 - 3.3e-09 36.3 1.0 3.7e-06 26.6 0.0 3.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO00870.1 - 1.7e-07 30.6 0.3 1.4e-06 27.7 0.1 2.3 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETO00870.1 - 5.5e-07 29.4 2.8 0.00035 20.6 0.1 3.7 3 1 1 4 4 4 1 Kelch motif Kelch_3 PF13415.1 ETO00870.1 - 0.00019 21.5 0.0 0.00075 19.5 0.0 2.0 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO00870.1 - 0.012 15.6 0.3 0.14 12.1 0.2 2.5 3 0 0 3 3 3 0 Kelch motif DUF2415 PF10313.4 ETO00870.1 - 0.029 14.0 0.0 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) DUF1828 PF08861.5 ETO00871.1 - 0.19 11.4 2.6 0.5 10.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF1828 Syntaxin-18_N PF10496.4 ETO00871.1 - 6.8 6.5 7.6 1.9 8.3 0.4 2.5 2 1 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus INCENP_N PF12178.3 ETO00872.1 - 1.2 8.7 5.6 0.44 10.1 0.2 2.6 2 0 0 2 2 2 0 Chromosome passenger complex (CPC) protein INCENP N terminal WD40 PF00400.27 ETO00874.1 - 1.4e-13 50.1 1.0 9.4e-12 44.3 0.0 2.4 2 1 0 2 2 2 2 WD domain, G-beta repeat TPR_12 PF13424.1 ETO00875.1 - 4.7e-07 29.6 0.0 6.4e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO00875.1 - 0.00042 19.8 0.2 1.1 9.1 0.0 2.4 2 1 0 2 2 2 2 Tetratricopeptide repeat RPN7 PF10602.4 ETO00875.1 - 0.0091 15.3 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_8 PF13181.1 ETO00875.1 - 0.0099 15.5 1.0 0.058 13.1 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO00875.1 - 0.011 15.5 0.7 1.8 8.6 0.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETO00875.1 - 0.023 14.2 0.6 0.52 10.0 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 ETO00875.1 - 0.061 12.9 0.1 0.15 11.7 0.1 1.7 1 1 1 2 2 2 0 TPR repeat bZIP_1 PF00170.16 ETO00875.1 - 0.098 12.6 0.1 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 bZIP transcription factor RVT_1 PF00078.22 ETO00876.1 - 7.3e-07 28.7 1.1 1.1e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 ETO00876.1 - 0.00063 19.3 0.0 0.0017 17.9 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase AflR PF08493.5 ETO00877.1 - 0.83 8.6 16.2 1.6 7.7 11.0 1.6 1 1 0 1 1 1 0 Aflatoxin regulatory protein GpcrRhopsn4 PF10192.4 ETO00878.1 - 0.023 13.8 2.4 0.033 13.3 1.4 1.3 1 1 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain PTR2 PF00854.16 ETO00878.1 - 0.031 13.0 0.4 0.036 12.8 0.3 1.1 1 0 0 1 1 1 0 POT family DUF3169 PF11368.3 ETO00878.1 - 0.04 13.1 3.4 0.085 12.0 1.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) OSTMP1 PF09777.4 ETO00878.1 - 0.093 11.8 1.4 0.12 11.5 0.4 1.6 1 1 1 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor MSC PF09402.5 ETO00878.1 - 0.17 10.5 3.8 0.18 10.4 2.6 1.3 1 1 0 1 1 1 0 Man1-Src1p-C-terminal domain DUF3753 PF12575.3 ETO00878.1 - 0.27 11.0 5.2 0.77 9.5 3.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3753) Glucos_trans_II PF14264.1 ETO00878.1 - 0.27 10.1 3.5 0.65 8.9 2.6 1.5 1 1 0 1 1 1 0 Glucosyl transferase GtrII Sigma_reg_N PF13800.1 ETO00878.1 - 0.54 10.3 5.3 0.2 11.6 1.9 1.7 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Oxidored_q4 PF00507.14 ETO00878.1 - 0.68 9.7 4.8 6.1 6.7 1.0 2.2 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Presenilin PF01080.12 ETO00878.1 - 1.9 7.2 4.8 2.5 6.8 3.2 1.3 1 1 0 1 1 1 0 Presenilin EMP24_GP25L PF01105.19 ETO00878.1 - 2.2 7.9 6.6 0.54 9.9 1.6 1.9 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD IncA PF04156.9 ETO00879.1 - 0.012 15.1 11.6 0.012 15.1 8.0 1.2 1 0 0 1 1 1 0 IncA protein CAF-1_p150 PF11600.3 ETO00879.1 - 0.27 10.5 26.7 0.44 9.8 18.5 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF342 PF03961.8 ETO00879.1 - 0.42 8.9 13.2 0.6 8.4 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Exonuc_VII_L PF02601.10 ETO00879.1 - 1.2 8.2 14.1 1.7 7.7 9.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3552 PF12072.3 ETO00879.1 - 1.7 7.8 34.6 6.2 5.9 24.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Serinc PF03348.10 ETO00879.1 - 3.1 6.4 8.6 7 5.2 6.0 1.6 1 1 0 1 1 1 0 Serine incorporator (Serinc) Kelch_6 PF13964.1 ETO00880.1 - 0.0028 17.7 0.1 0.05 13.8 0.0 2.6 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.1 ETO00880.1 - 0.044 13.7 0.0 20 5.2 0.0 3.1 3 0 0 3 3 3 0 Kelch motif Kelch_1 PF01344.20 ETO00880.1 - 0.047 13.2 0.2 0.77 9.3 0.0 2.5 2 0 0 2 2 2 0 Kelch motif COesterase PF00135.23 ETO00882.1 - 1.4e-05 24.0 0.0 1.4e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Tup_N PF08581.5 ETO00884.1 - 0.018 15.2 3.0 0.53 10.5 0.6 2.3 2 0 0 2 2 2 0 Tup N-terminal DUF641 PF04859.7 ETO00884.1 - 0.04 13.6 5.0 0.95 9.2 1.0 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Bap31 PF05529.7 ETO00884.1 - 0.057 12.8 8.6 0.72 9.2 0.2 2.1 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Geminin PF07412.7 ETO00884.1 - 0.14 11.8 5.2 1.6 8.4 0.1 2.1 2 0 0 2 2 2 0 Geminin HSCB_C PF07743.8 ETO00884.1 - 0.19 12.1 3.8 0.47 10.9 2.7 1.7 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain Tnp_P_element PF12017.3 ETO00884.1 - 0.38 9.9 6.5 3.6 6.7 1.2 2.0 1 1 1 2 2 2 0 Transposase protein CASP_C PF08172.7 ETO00884.1 - 0.45 9.5 3.6 0.77 8.7 2.5 1.6 1 1 0 1 1 1 0 CASP C terminal DUF1640 PF07798.6 ETO00884.1 - 0.78 9.7 7.3 0.29 11.1 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) FlxA PF14282.1 ETO00884.1 - 0.79 9.6 6.1 0.3 11.0 1.3 1.9 2 0 0 2 2 2 0 FlxA-like protein Cep57_CLD_2 PF14197.1 ETO00884.1 - 0.92 9.4 5.4 83 3.2 0.2 2.9 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 DivIC PF04977.10 ETO00884.1 - 1.4 8.4 10.6 4.1 6.9 0.2 2.6 1 1 2 3 3 3 0 Septum formation initiator Herpes_BLRF2 PF05812.7 ETO00884.1 - 1.7 8.4 6.4 2 8.2 2.1 2.2 2 1 0 2 2 2 0 Herpesvirus BLRF2 protein ubiquitin PF00240.18 ETO00884.1 - 1.9 7.9 7.0 1.6 8.1 0.8 2.2 1 1 0 2 2 2 0 Ubiquitin family bZIP_1 PF00170.16 ETO00884.1 - 2 8.4 8.4 3 7.8 0.2 2.9 2 1 1 3 3 3 0 bZIP transcription factor SPT16 PF08644.6 ETO00884.1 - 2.4 7.9 6.6 17 5.2 4.5 1.9 1 1 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) DUF4201 PF13870.1 ETO00884.1 - 2.6 7.4 13.0 1.4 8.2 1.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Myosin_tail_1 PF01576.14 ETO00884.1 - 2.8 5.5 8.2 6.6 4.3 5.7 1.6 1 1 0 1 1 1 0 Myosin tail CUE PF02845.11 ETO00885.1 - 0.028 13.9 0.0 0.06 12.8 0.0 1.6 1 0 0 1 1 1 0 CUE domain WxL PF13731.1 ETO00890.1 - 0.039 13.7 0.1 0.044 13.5 0.1 1.1 1 0 0 1 1 1 0 WxL domain surface cell wall-binding SBF2 PF12335.3 ETO00891.1 - 0.0046 16.3 2.5 0.0046 16.3 1.8 1.9 1 1 1 2 2 2 1 Myotubularin protein Pkinase PF00069.20 ETO00892.1 - 4.1e-19 68.7 0.1 4.9e-19 68.4 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO00892.1 - 4.3e-11 42.3 0.0 5.1e-11 42.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO00892.1 - 0.072 12.1 0.1 0.092 11.8 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 ETO00892.1 - 0.081 12.4 0.3 0.14 11.7 0.2 1.3 1 1 0 1 1 1 0 Choline/ethanolamine kinase eRF1_1 PF03463.10 ETO00893.1 - 1.5e-09 37.4 0.0 1e-08 34.7 0.0 2.0 1 1 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 ETO00893.1 - 2.9e-05 24.4 0.0 5.9e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 eRF1 domain 2 NOSIC PF08060.8 ETO00894.1 - 0.1 12.4 0.0 0.43 10.4 0.0 2.1 1 0 0 1 1 1 0 NOSIC (NUC001) domain DUF262 PF03235.9 ETO00895.1 - 0.039 13.9 2.9 0.039 13.9 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 Vfa1 PF08432.5 ETO00895.1 - 0.098 12.6 12.6 0.12 12.4 8.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CMV_1a PF12467.3 ETO00895.1 - 0.15 12.4 7.2 0.19 12.0 5.0 1.1 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family SET PF00856.23 ETO00895.1 - 0.15 12.3 0.8 0.19 12.0 0.6 1.1 1 0 0 1 1 1 0 SET domain OATP PF03137.15 ETO00895.1 - 0.16 9.9 3.1 0.19 9.7 2.2 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family RNA_pol_Rpb1_5 PF04998.12 ETO00895.1 - 0.53 9.4 5.5 0.56 9.4 3.8 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 PEX11 PF05648.9 ETO00895.1 - 1.2 8.4 7.9 2.7 7.1 5.5 1.7 1 1 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) SecA_PP_bind PF01043.15 ETO00895.1 - 1.6 9.1 7.2 2.8 8.3 3.3 2.1 2 0 0 2 2 2 0 SecA preprotein cross-linking domain Hom_end_hint PF05203.11 ETO00895.1 - 2 8.0 8.4 2.5 7.7 5.8 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint YqfQ PF14181.1 ETO00895.1 - 8.1 6.4 11.8 11 6.0 8.2 1.2 1 0 0 1 1 1 0 YqfQ-like protein Poty_PP PF08440.5 ETO00898.1 - 0.003 16.6 2.0 0.0037 16.3 1.4 1.1 1 0 0 1 1 1 1 Potyviridae polyprotein JHBP PF06585.6 ETO00898.1 - 0.0031 16.3 1.2 0.0043 15.9 0.2 1.6 2 0 0 2 2 2 1 Haemolymph juvenile hormone binding protein (JHBP) Radial_spoke PF04712.7 ETO00898.1 - 0.0031 16.3 1.2 0.0038 16.0 0.8 1.1 1 0 0 1 1 1 1 Radial spokehead-like protein DUF3802 PF12290.3 ETO00898.1 - 0.0045 17.2 0.5 0.11 12.8 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3802) RHD3 PF05879.7 ETO00898.1 - 0.013 13.5 2.1 0.016 13.2 1.4 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) UBN2 PF14223.1 ETO00898.1 - 0.095 12.4 3.0 1.5 8.5 0.3 2.9 2 1 1 3 3 3 0 gag-polypeptide of LTR copia-type TelA PF05816.6 ETO00898.1 - 0.11 11.1 0.1 0.11 11.1 0.1 1.8 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) YlbD_coat PF14071.1 ETO00898.1 - 0.13 12.3 2.8 0.85 9.6 0.5 2.1 2 0 0 2 2 2 0 Putative coat protein Sec8_exocyst PF04048.9 ETO00898.1 - 0.17 11.4 3.0 0.46 10.0 0.2 2.1 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Img2 PF05046.9 ETO00898.1 - 0.36 11.0 2.4 1.7 8.8 1.7 2.2 1 1 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) Vps51 PF08700.6 ETO00898.1 - 0.51 10.2 3.2 0.39 10.5 0.3 2.1 2 1 0 2 2 2 0 Vps51/Vps67 MitMem_reg PF13012.1 ETO00898.1 - 0.84 9.7 6.4 0.85 9.7 0.2 2.3 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function FlaC_arch PF05377.6 ETO00898.1 - 3.1 7.7 7.7 19 5.2 0.4 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Cellulase PF00150.13 ETO00899.1 - 0.017 14.3 0.9 0.02 14.0 0.6 1.1 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) DUF4124 PF13511.1 ETO00899.1 - 0.09 12.8 0.2 0.12 12.4 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4124) TSA PF03249.8 ETO00899.1 - 0.9 8.0 4.6 1 7.8 3.2 1.1 1 0 0 1 1 1 0 Type specific antigen Med3 PF11593.3 ETO00899.1 - 1.8 7.7 7.1 2.3 7.3 5.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal BAF1_ABF1 PF04684.8 ETO00899.1 - 2.3 6.9 5.3 2.6 6.7 3.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor HtrL_YibB PF09612.5 ETO00901.1 - 0.037 13.2 0.9 0.057 12.6 0.1 1.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (HtrL_YibB) STAT_alpha PF01017.15 ETO00902.1 - 0.0024 17.6 6.4 0.0027 17.4 4.4 1.1 1 0 0 1 1 1 1 STAT protein, all-alpha domain Tmemb_cc2 PF10267.4 ETO00902.1 - 0.0071 14.9 8.7 0.0088 14.6 6.0 1.1 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein APG6 PF04111.7 ETO00902.1 - 0.077 12.0 9.0 0.084 11.8 6.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 ETO00902.1 - 0.14 10.5 7.7 0.15 10.4 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Fib_alpha PF08702.5 ETO00902.1 - 0.27 11.3 8.1 0.4 10.7 5.6 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF724 PF05266.9 ETO00902.1 - 0.37 10.3 6.8 0.4 10.2 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) OB_NTP_bind PF07717.11 ETO00902.1 - 0.63 9.8 3.3 4.4 7.1 2.3 2.0 1 1 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold EST1_DNA_bind PF10373.4 ETO00902.1 - 0.64 9.1 4.2 0.77 8.9 2.9 1.3 1 1 0 1 1 1 0 Est1 DNA/RNA binding domain Seryl_tRNA_N PF02403.17 ETO00902.1 - 0.71 9.9 10.9 0.99 9.4 7.5 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain PspB PF06667.7 ETO00902.1 - 1.9 8.4 4.9 0.83 9.6 1.6 1.8 2 0 0 2 2 2 0 Phage shock protein B DUF904 PF06005.7 ETO00902.1 - 2.2 8.6 13.4 3.1 8.1 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF904) TMF_DNA_bd PF12329.3 ETO00902.1 - 5.5 6.8 16.2 11 5.8 10.8 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF2951 PF11166.3 ETO00902.1 - 7.9 6.4 10.7 5.2 6.9 6.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) IncA PF04156.9 ETO00902.1 - 8.7 5.8 10.3 11 5.5 7.1 1.2 1 0 0 1 1 1 0 IncA protein Abi_2 PF07751.6 ETO00907.1 - 0.053 13.6 0.8 0.085 13.0 0.4 1.3 1 1 0 1 1 1 0 Abi-like protein AnfG_VnfG PF03139.10 ETO00907.1 - 0.11 12.3 1.6 0.13 12.0 1.1 1.2 1 0 0 1 1 1 0 Vanadium/alternative nitrogenase delta subunit Phyto_Pns9_10 PF05878.6 ETO00908.1 - 0.2 10.6 3.0 0.22 10.5 2.1 1.0 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 Thr_synth_N PF14821.1 ETO00909.1 - 0.034 14.1 0.0 1.6 8.7 0.0 2.1 2 0 0 2 2 2 0 Threonine synthase N terminus DUF3543 PF12063.3 ETO00911.1 - 1.6e-06 27.4 1.9 3.7e-06 26.3 1.3 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) DUF948 PF06103.6 ETO00912.1 - 0.015 15.1 2.5 0.018 14.8 1.7 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Lac_bphage_repr PF06543.7 ETO00912.1 - 0.041 13.4 1.9 0.25 10.8 0.1 2.6 2 1 1 3 3 3 0 Lactococcus bacteriophage repressor Rho_Binding PF08912.6 ETO00912.1 - 0.58 10.4 8.3 0.24 11.7 4.3 1.5 2 0 0 2 2 2 0 Rho Binding RNA_pol_Rpb5_C PF01191.14 ETO00914.1 - 0.027 14.0 0.6 0.53 9.9 0.1 2.2 1 1 1 2 2 2 0 RNA polymerase Rpb5, C-terminal domain Pkinase PF00069.20 ETO00915.1 - 6.6e-12 45.1 1.8 8.4e-12 44.7 1.3 1.1 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 ETO00917.1 - 4.1e-19 67.6 7.4 4.4e-10 39.0 0.4 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO00917.1 - 5.2e-05 21.5 1.6 0.0023 16.1 0.2 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 SecA_SW PF07516.8 ETO00919.1 - 0.081 12.6 0.4 6.3 6.4 0.0 2.1 2 0 0 2 2 2 0 SecA Wing and Scaffold domain Pox_E10 PF04805.7 ETO00920.1 - 0.013 14.9 0.2 0.027 13.9 0.2 1.6 1 0 0 1 1 1 0 E10-like protein conserved region AAA_18 PF13238.1 ETO00921.1 - 1.1e-07 32.2 1.7 3.2e-06 27.4 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 ETO00921.1 - 7.8e-06 26.7 0.5 0.00071 20.3 0.0 2.1 1 1 1 2 2 2 1 AAA domain NACHT PF05729.7 ETO00921.1 - 9e-05 22.1 0.0 0.00018 21.2 0.0 1.5 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 ETO00921.1 - 0.00015 21.9 0.0 0.00071 19.7 0.0 1.9 1 1 1 2 2 2 1 AAA domain UPF0079 PF02367.12 ETO00921.1 - 0.0005 19.6 0.0 0.0007 19.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 ETO00921.1 - 0.0006 19.7 0.0 0.0014 18.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain ATP_bind_2 PF03668.10 ETO00921.1 - 0.0036 16.4 0.0 0.0053 15.8 0.0 1.3 1 0 0 1 1 1 1 P-loop ATPase protein family AAA_5 PF07728.9 ETO00921.1 - 0.0076 15.9 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 ETO00921.1 - 0.0077 16.3 3.5 0.016 15.3 0.0 2.2 2 1 0 2 2 2 1 RNA helicase PRK PF00485.13 ETO00921.1 - 0.0079 15.7 0.1 0.016 14.7 0.0 1.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family DUF258 PF03193.11 ETO00921.1 - 0.0093 15.1 0.2 0.012 14.7 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 G-alpha PF00503.15 ETO00921.1 - 0.0099 14.5 5.4 0.022 13.4 3.8 1.6 1 1 0 1 1 1 1 G-protein alpha subunit Zeta_toxin PF06414.7 ETO00921.1 - 0.015 14.3 0.1 0.034 13.2 0.0 1.5 1 1 0 1 1 1 0 Zeta toxin PPV_E1_C PF00519.12 ETO00921.1 - 0.016 13.8 0.0 0.02 13.5 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase VirE PF05272.6 ETO00921.1 - 0.019 14.4 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Virulence-associated protein E DAP3 PF10236.4 ETO00921.1 - 0.027 13.3 0.7 0.046 12.6 0.4 1.7 1 1 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Sigma54_activat PF00158.21 ETO00921.1 - 0.029 13.8 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.1 ETO00921.1 - 0.029 14.3 0.0 0.038 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Torsin PF06309.6 ETO00921.1 - 0.035 14.0 0.1 0.061 13.2 0.0 1.4 1 1 0 1 1 1 0 Torsin PduV-EutP PF10662.4 ETO00921.1 - 0.039 13.4 0.0 0.091 12.2 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.9 ETO00921.1 - 0.055 12.4 0.0 0.061 12.3 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA_29 PF13555.1 ETO00921.1 - 0.055 13.0 0.0 0.089 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 ETO00921.1 - 0.058 13.7 0.5 0.091 13.0 0.2 1.6 1 1 0 1 1 1 0 ABC transporter AAA_30 PF13604.1 ETO00921.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain IL15 PF02372.10 ETO00921.1 - 0.15 11.8 3.8 0.04 13.6 0.7 1.5 2 0 0 2 2 2 0 Interleukin 15 AAA_14 PF13173.1 ETO00921.1 - 0.56 10.1 4.0 1.8 8.5 0.1 2.2 2 1 0 2 2 2 0 AAA domain MSC PF09402.5 ETO00921.1 - 0.72 8.5 4.5 1.1 7.8 0.9 1.8 1 1 1 2 2 2 0 Man1-Src1p-C-terminal domain AAA_10 PF12846.2 ETO00921.1 - 6.9 6.0 6.9 1.1e+02 2.0 4.8 2.4 1 1 0 1 1 1 0 AAA-like domain Cnd1 PF12717.2 ETO00922.1 - 0.00015 21.6 2.7 0.00022 21.1 1.9 1.3 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Bac_DNA_binding PF00216.16 ETO00922.1 - 0.0038 17.2 1.2 0.032 14.2 0.5 2.2 2 1 0 2 2 2 1 Bacterial DNA-binding protein Rhabdo_glycop PF00974.13 ETO00922.1 - 0.0045 15.2 2.5 0.006 14.8 1.7 1.1 1 0 0 1 1 1 1 Rhabdovirus spike glycoprotein HEAT_2 PF13646.1 ETO00922.1 - 0.0068 16.6 0.0 0.013 15.7 0.0 1.5 2 0 0 2 2 1 1 HEAT repeats PRD PF00874.15 ETO00922.1 - 0.015 15.4 0.7 0.032 14.3 0.5 1.6 1 0 0 1 1 1 0 PRD domain RP-C_C PF11800.3 ETO00922.1 - 0.015 15.0 2.2 0.02 14.6 1.5 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Baculo_PEP_C PF04513.7 ETO00922.1 - 0.031 14.1 2.2 0.24 11.1 1.5 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DSHCT PF08148.7 ETO00922.1 - 0.031 13.5 0.3 0.18 11.0 0.0 1.9 1 1 1 2 2 2 0 DSHCT (NUC185) domain HEAT PF02985.17 ETO00922.1 - 0.035 14.1 0.2 0.43 10.7 0.0 2.7 2 2 1 3 3 3 0 HEAT repeat IncA PF04156.9 ETO00922.1 - 0.06 12.9 9.2 0.056 13.0 5.9 1.3 1 1 0 1 1 1 0 IncA protein GlutR_dimer PF00745.15 ETO00922.1 - 0.13 12.2 2.7 0.23 11.3 0.4 2.3 1 1 1 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain PAS_10 PF13596.1 ETO00922.1 - 0.16 12.2 0.7 1 9.6 0.2 2.3 1 1 2 3 3 3 0 PAS domain DUF445 PF04286.7 ETO00922.1 - 0.17 11.3 3.2 0.21 11.0 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF1002 PF06207.6 ETO00922.1 - 0.18 11.1 4.4 0.22 10.7 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) XkdW PF09636.5 ETO00922.1 - 0.28 11.0 2.9 0.3 10.9 0.6 2.0 1 1 1 2 2 2 0 XkdW protein ETC_C1_NDUFA5 PF04716.9 ETO00922.1 - 0.44 10.1 2.3 1.4 8.5 0.2 2.5 2 1 0 2 2 2 0 ETC complex I subunit conserved region CAAP1 PF15335.1 ETO00922.1 - 0.66 10.2 5.0 0.95 9.7 0.8 2.5 2 0 0 2 2 2 0 Caspase activity and apoptosis inhibitor 1 HSCB_C PF07743.8 ETO00922.1 - 0.89 10.0 5.4 3.8 8.0 2.4 2.5 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain Cep57_MT_bd PF06657.8 ETO00922.1 - 1.2 9.1 5.2 0.27 11.1 0.3 2.3 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 UPF0184 PF03670.8 ETO00922.1 - 2 8.6 5.1 12 6.1 0.1 2.5 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0184) Met_10 PF02475.11 ETO00924.1 - 0.017 14.7 0.1 0.021 14.4 0.1 1.1 1 0 0 1 1 1 0 Met-10+ like-protein DUF4181 PF13789.1 ETO00924.1 - 0.071 13.0 4.6 0.58 10.0 3.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4181) UPF0014 PF03649.8 ETO00924.1 - 0.09 11.9 0.4 0.11 11.6 0.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0014) DUF1509 PF07420.6 ETO00925.1 - 0.024 13.9 0.8 0.024 13.9 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1509) RXT2_N PF08595.6 ETO00925.1 - 0.81 9.4 9.0 2.4 7.9 1.0 2.2 1 1 1 2 2 2 0 RXT2-like, N-terminal Kelch_5 PF13854.1 ETO00926.1 - 0.095 12.6 0.6 0.095 12.6 0.4 1.7 2 0 0 2 2 2 0 Kelch motif Kelch_6 PF13964.1 ETO00926.1 - 0.37 11.0 2.9 0.22 11.7 0.6 1.7 2 0 0 2 2 2 0 Kelch motif AAA_22 PF13401.1 ETO00927.1 - 0.0022 18.1 0.1 0.008 16.3 0.0 1.9 1 1 2 3 3 3 1 AAA domain NACHT PF05729.7 ETO00927.1 - 0.033 13.8 0.2 0.057 13.0 0.1 1.6 1 1 0 1 1 1 0 NACHT domain AAA PF00004.24 ETO00927.1 - 0.052 13.7 0.4 0.16 12.2 0.3 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 ETO00927.1 - 0.073 12.7 0.4 0.62 9.7 0.2 2.1 1 1 0 1 1 1 0 NTPase OST-HTH PF12872.2 ETO00927.1 - 0.079 12.8 0.8 0.27 11.0 0.1 2.2 3 0 0 3 3 3 0 OST-HTH/LOTUS domain Flavi_glycoprot PF00869.15 ETO00928.1 - 0.0065 15.4 0.6 0.0069 15.4 0.4 1.2 1 0 0 1 1 1 1 Flavivirus glycoprotein, central and dimerisation domains DUF1400 PF07176.6 ETO00928.1 - 0.063 13.1 0.3 0.1 12.5 0.1 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1400) SSPI PF14098.1 ETO00928.1 - 0.32 10.9 0.3 0.32 10.9 0.2 2.4 3 0 0 3 3 3 0 Small, acid-soluble spore protein I TPR_12 PF13424.1 ETO00929.1 - 9e-122 397.2 59.9 6.4e-23 80.4 1.8 4.9 1 1 6 7 7 7 7 Tetratricopeptide repeat TPR_11 PF13414.1 ETO00929.1 - 3.3e-53 177.2 51.3 5.4e-15 54.7 6.5 6.2 3 2 2 5 5 5 5 TPR repeat TPR_1 PF00515.23 ETO00929.1 - 2.9e-48 159.6 59.9 2.3e-09 36.4 1.3 8.1 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_10 PF13374.1 ETO00929.1 - 2.5e-47 157.5 0.2 1.1e-08 34.7 0.0 7.8 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETO00929.1 - 3e-45 148.4 49.4 8.7e-08 31.5 0.6 8.1 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.1 ETO00929.1 - 1.4e-42 140.2 56.5 2.6e-07 29.9 1.4 7.8 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_7 PF13176.1 ETO00929.1 - 1.4e-38 127.6 17.9 6.5e-05 22.4 0.1 8.1 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 ETO00929.1 - 4e-31 106.9 0.9 1.9e-09 37.9 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO00929.1 - 3.4e-28 95.5 0.3 0.0033 17.9 0.0 7.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.1 ETO00929.1 - 7.4e-24 82.5 14.9 0.0047 17.3 0.0 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat Apc3 PF12895.2 ETO00929.1 - 1.5e-17 63.5 34.8 2e-06 27.8 3.8 5.8 1 1 4 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 ETO00929.1 - 3.9e-17 60.9 23.3 0.0026 17.7 0.5 8.2 7 3 0 7 7 7 4 Tetratricopeptide repeat SNAP PF14938.1 ETO00929.1 - 8.5e-17 61.2 22.5 1.7e-08 34.0 8.4 3.6 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP SHNi-TPR PF10516.4 ETO00929.1 - 2.2e-13 49.1 7.3 0.17 11.1 0.0 7.5 8 0 0 8 8 8 3 SHNi-TPR TPR_19 PF14559.1 ETO00929.1 - 1.8e-12 47.4 13.1 0.00019 21.6 0.2 5.5 3 1 4 7 7 7 5 Tetratricopeptide repeat MIT PF04212.13 ETO00929.1 - 4.6e-08 32.8 36.2 0.4 10.5 0.6 7.4 7 1 1 8 8 7 4 MIT (microtubule interacting and transport) domain DUF2225 PF09986.4 ETO00929.1 - 8.5e-07 28.6 31.2 0.19 11.1 4.3 4.5 1 1 2 3 3 3 3 Uncharacterized protein conserved in bacteria (DUF2225) TPR_3 PF07720.7 ETO00929.1 - 1.3e-06 28.0 43.3 0.015 15.0 0.7 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat Sel1 PF08238.7 ETO00929.1 - 7.1e-06 26.4 28.9 3.1 8.5 0.6 7.5 7 0 0 7 7 7 1 Sel1 repeat PPR PF01535.15 ETO00929.1 - 1.4e-05 24.6 10.0 0.49 10.4 0.1 6.5 7 0 0 7 7 7 2 PPR repeat ATP-synt_D PF01813.12 ETO00929.1 - 0.00023 20.7 2.5 19 4.6 0.0 5.5 1 1 2 4 4 4 0 ATP synthase subunit D TPR_21 PF09976.4 ETO00929.1 - 0.0007 19.5 7.3 0.071 13.0 0.8 4.1 1 1 2 3 3 3 1 Tetratricopeptide repeat ATP-synt_E_2 PF08112.6 ETO00929.1 - 0.00079 19.4 11.3 9.5 6.3 0.0 6.4 6 1 1 7 7 6 0 ATP synthase epsilon subunit DUF627 PF04781.7 ETO00929.1 - 0.0034 16.9 15.2 0.46 10.1 0.2 5.8 2 1 1 5 5 5 1 Protein of unknown function (DUF627) DUF3368 PF11848.3 ETO00929.1 - 0.004 16.6 2.0 27 4.4 0.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF3368) RPN7 PF10602.4 ETO00929.1 - 0.0068 15.8 22.2 0.41 9.9 0.1 5.7 4 1 1 6 6 6 1 26S proteasome subunit RPN7 DUF2753 PF10952.3 ETO00929.1 - 0.011 15.6 2.1 17 5.4 0.1 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF2753) TPR_5 PF12688.2 ETO00929.1 - 0.014 15.4 2.6 1.2 9.1 0.0 4.4 3 2 2 5 5 5 0 Tetratrico peptide repeat DUF424 PF04242.8 ETO00929.1 - 0.016 15.2 2.9 7.3 6.7 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF424) NSF PF02071.15 ETO00929.1 - 0.029 14.8 33.2 30 5.8 0.2 8.9 8 0 0 8 8 8 0 Aromatic-di-Alanine (AdAR) repeat DUF3536 PF12055.3 ETO00929.1 - 0.04 13.0 3.7 2.6 7.1 0.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3536) TPR_20 PF14561.1 ETO00929.1 - 0.099 12.7 4.7 28 4.9 0.0 4.9 3 2 2 5 5 5 0 Tetratricopeptide repeat Mg-por_mtran_C PF07109.6 ETO00929.1 - 0.12 12.4 0.3 0.47 10.5 0.0 2.1 2 0 0 2 2 2 0 Magnesium-protoporphyrin IX methyltransferase C-terminus Ubiq_cyt_C_chap PF03981.7 ETO00929.1 - 0.13 12.1 2.0 3.8 7.3 0.0 3.7 1 1 3 5 5 5 0 Ubiquinol-cytochrome C chaperone DBD_Tnp_Mut PF03108.10 ETO00929.1 - 0.28 10.7 4.9 3.6 7.2 0.0 4.3 6 0 0 6 6 4 0 MuDR family transposase Fib_alpha PF08702.5 ETO00929.1 - 0.47 10.5 4.7 9.4 6.3 0.1 3.1 1 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Foie-gras_1 PF11817.3 ETO00929.1 - 0.61 9.5 13.8 2.1 7.7 0.2 4.8 3 1 3 6 6 6 0 Foie gras liver health family 1 NYD-SP28_assoc PF14775.1 ETO00929.1 - 0.98 9.1 11.1 29 4.4 0.1 5.1 5 0 0 5 5 5 0 Sperm tail C-terminal domain TCTP PF00838.12 ETO00929.1 - 1.2 9.1 15.0 0.3 11.0 0.1 4.4 2 2 3 5 5 5 0 Translationally controlled tumour protein DUF4249 PF14054.1 ETO00929.1 - 1.7 7.9 16.3 9.4 5.4 1.6 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4249) UVR PF02151.14 ETO00929.1 - 2 8.0 13.8 12 5.5 0.1 5.7 7 0 0 7 7 6 0 UvrB/uvrC motif Sec5 PF15469.1 ETO00929.1 - 2.1 8.0 25.6 2.7 7.6 0.3 5.3 4 2 0 4 4 4 0 Exocyst complex component Sec5 Vps39_1 PF10366.4 ETO00929.1 - 2.5 8.1 15.6 7.2 6.6 0.1 5.1 1 1 2 4 4 4 0 Vacuolar sorting protein 39 domain 1 Prefoldin PF02996.12 ETO00929.1 - 3.9 7.1 12.8 5 6.8 0.0 4.8 6 0 0 6 6 6 0 Prefoldin subunit GH97_C PF14509.1 ETO00929.1 - 9 6.4 8.9 4.1 7.5 0.2 3.4 4 1 1 5 5 4 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation DHC_N1 PF08385.7 ETO00931.1 - 8.9e-30 103.6 0.3 1.3e-29 103.0 0.2 1.4 1 1 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 DUF3439 PF11921.3 ETO00931.1 - 0.38 10.5 4.6 0.6 9.8 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Arc_PepC PF06819.6 ETO00932.1 - 0.024 14.5 0.1 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain YfbU PF03887.9 ETO00932.1 - 0.035 13.6 0.5 0.042 13.4 0.4 1.1 1 0 0 1 1 1 0 YfbU domain Pkinase PF00069.20 ETO00934.1 - 9.8e-19 67.5 0.3 2.1e-18 66.3 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO00934.1 - 1.7e-16 60.0 0.0 3.7e-16 58.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO00934.1 - 3e-08 32.9 0.0 4.7e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PIP49_C PF12260.3 ETO00934.1 - 0.014 14.8 0.0 0.032 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Clostridium_P47 PF06597.6 ETO00934.1 - 0.037 12.5 0.1 0.067 11.7 0.0 1.3 1 0 0 1 1 1 0 Clostridium P-47 protein TSA PF03249.8 ETO00934.1 - 0.24 9.8 3.7 0.39 9.2 2.5 1.3 1 0 0 1 1 1 0 Type specific antigen PWWP PF00855.12 ETO00936.1 - 1.5e-07 31.5 0.8 1.5e-07 31.5 0.5 2.2 2 0 0 2 2 2 1 PWWP domain POP1 PF06978.6 ETO00936.1 - 0.052 13.2 3.9 0.06 12.9 2.7 1.1 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 DUF4262 PF14081.1 ETO00936.1 - 0.1 12.7 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4262) DUF296 PF03479.10 ETO00936.1 - 0.11 12.0 0.0 0.21 11.2 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF296) Costars PF14705.1 ETO00938.1 - 0.018 15.0 0.7 0.075 13.0 0.2 2.3 2 0 0 2 2 2 0 Costars PilJ PF13675.1 ETO00938.1 - 0.13 12.5 12.3 0.79 10.0 4.3 2.6 1 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Chordopox_G3 PF06129.7 ETO00938.1 - 7.7 6.7 7.8 2.4 8.3 0.1 3.1 2 2 1 3 3 3 0 Chordopoxvirus G3 protein Cnd1 PF12717.2 ETO00939.1 - 2.3e-05 24.3 1.7 0.0019 18.0 0.0 2.6 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.5 ETO00939.1 - 0.00025 20.6 0.5 0.35 10.4 0.0 2.7 1 1 1 2 2 2 2 TATA-binding protein interacting (TIP20) DUF2435 PF10363.4 ETO00939.1 - 0.0013 18.6 0.3 0.35 10.7 0.0 3.6 4 0 0 4 4 4 1 Protein of unknown function (DUF2435) NLE PF08154.7 ETO00939.1 - 0.0089 16.0 1.0 0.49 10.4 0.0 3.5 4 1 0 4 4 4 1 NLE (NUC135) domain HEAT_2 PF13646.1 ETO00939.1 - 0.033 14.4 0.0 0.092 13.0 0.0 1.9 1 1 1 2 2 2 0 HEAT repeats SNARE PF05739.14 ETO00940.1 - 0.00032 20.3 1.5 0.00072 19.1 1.0 1.6 1 0 0 1 1 1 1 SNARE domain HSP70 PF00012.15 ETO00941.1 - 0.083 10.7 3.3 0.08 10.8 1.8 1.3 1 1 0 1 1 1 0 Hsp70 protein zf-AD PF07776.10 ETO00941.1 - 0.12 12.3 1.2 0.23 11.5 0.1 2.0 1 1 0 1 1 1 0 Zinc-finger associated domain (zf-AD) Endonuclease_NS PF01223.18 ETO00942.1 - 8.1e-28 97.4 1.1 1.1e-24 87.2 0.1 2.3 1 1 1 2 2 2 2 DNA/RNA non-specific endonuclease GDI PF00996.13 ETO00942.1 - 0.016 13.5 0.0 0.036 12.3 0.0 1.6 1 0 0 1 1 1 0 GDP dissociation inhibitor Glyco_hydro_7 PF00840.15 ETO00943.1 - 0.019 13.3 0.3 0.026 12.9 0.2 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 7 DUF328 PF03883.9 ETO00943.1 - 0.12 11.6 2.1 0.4 9.9 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF328) MSG PF02349.10 ETO00943.1 - 9.8 6.2 9.1 1.3 9.0 3.4 1.8 2 1 0 2 2 2 0 Major surface glycoprotein WD40 PF00400.27 ETO00944.1 - 2.7e-14 52.3 0.1 2.6e-08 33.4 0.0 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO00944.1 - 0.0025 16.0 0.0 0.0025 16.0 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO00944.1 - 0.0063 16.2 0.0 0.0094 15.7 0.0 1.3 1 1 0 1 1 1 1 Ciliary BBSome complex subunit 2, middle region PBP_sp32 PF07222.7 ETO00945.1 - 2.3 7.3 5.7 2.3 7.3 3.9 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 RNA_ligase PF09414.5 ETO00947.1 - 0.099 12.4 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 RNA ligase Peptidase_C14 PF00656.17 ETO00948.1 - 1.3e-08 34.9 0.1 1.7e-08 34.4 0.1 1.2 1 0 0 1 1 1 1 Caspase domain zf-TRAF PF02176.13 ETO00950.1 - 2.4e-07 31.0 3.8 3.3e-07 30.5 1.6 2.1 2 0 0 2 2 2 1 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 ETO00950.1 - 2 8.5 7.5 0.61 10.1 0.6 3.1 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) APP_E2 PF12925.2 ETO00951.1 - 0.32 10.5 2.7 1.2 8.6 0.1 2.6 3 0 0 3 3 3 0 E2 domain of amyloid precursor protein Nodulin_late PF07127.6 ETO00952.1 - 0.062 13.4 7.3 4.1 7.6 5.0 2.2 1 1 0 1 1 1 0 Late nodulin protein MT PF12777.2 ETO00953.1 - 4.1e-09 35.6 0.2 4.8e-09 35.4 0.2 1.1 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor DUF4201 PF13870.1 ETO00953.1 - 0.0024 17.3 5.5 0.0041 16.5 3.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) WEMBL PF05701.6 ETO00953.1 - 0.0035 15.8 6.0 0.0037 15.8 4.1 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Reo_sigmaC PF04582.7 ETO00953.1 - 0.0049 16.0 1.1 0.0059 15.8 0.8 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Laminin_II PF06009.7 ETO00953.1 - 0.0059 16.3 4.5 0.0059 16.3 3.1 1.8 1 1 1 2 2 2 1 Laminin Domain II DUF3584 PF12128.3 ETO00953.1 - 0.0065 13.8 4.1 0.0065 13.8 2.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Tropomyosin PF00261.15 ETO00953.1 - 0.0087 15.1 4.2 0.012 14.6 2.8 1.3 1 1 0 1 1 1 1 Tropomyosin Syntaxin PF00804.20 ETO00953.1 - 0.0088 16.1 2.3 0.0088 16.1 1.6 1.6 2 0 0 2 2 1 1 Syntaxin Myosin_tail_1 PF01576.14 ETO00953.1 - 0.0092 13.7 3.9 0.0051 14.6 1.4 1.4 2 0 0 2 2 2 1 Myosin tail CENP-F_leu_zip PF10473.4 ETO00953.1 - 0.013 15.3 7.5 0.014 15.2 4.7 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FliJ PF02050.11 ETO00953.1 - 0.014 15.4 2.5 0.014 15.4 1.8 1.6 2 0 0 2 2 1 0 Flagellar FliJ protein TMF_TATA_bd PF12325.3 ETO00953.1 - 0.018 14.7 4.4 0.033 13.9 3.0 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF812 PF05667.6 ETO00953.1 - 0.02 13.3 4.7 0.024 13.1 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF869 PF05911.6 ETO00953.1 - 0.021 13.1 6.3 0.023 12.9 4.4 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Fmp27_WPPW PF10359.4 ETO00953.1 - 0.021 13.2 4.1 0.037 12.4 2.9 1.5 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain RmuC PF02646.11 ETO00953.1 - 0.029 13.2 3.5 0.053 12.3 1.5 1.8 1 1 1 2 2 2 0 RmuC family Tropomyosin_1 PF12718.2 ETO00953.1 - 0.029 14.1 8.8 0.42 10.4 2.4 2.3 1 1 1 2 2 2 0 Tropomyosin like DUF4047 PF13256.1 ETO00953.1 - 0.031 14.2 0.6 0.031 14.2 0.4 1.4 2 0 0 2 2 1 0 Domain of unknown function (DUF4047) Flagellin_N PF00669.15 ETO00953.1 - 0.031 14.0 0.6 0.045 13.5 0.4 1.2 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region TPR_MLP1_2 PF07926.7 ETO00953.1 - 0.032 13.9 2.7 0.07 12.8 1.8 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF745 PF05335.8 ETO00953.1 - 0.036 13.5 1.6 0.052 13.0 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) TSC22 PF01166.13 ETO00953.1 - 0.037 13.9 1.1 0.091 12.7 0.4 1.9 1 1 0 1 1 1 0 TSC-22/dip/bun family COG2 PF06148.6 ETO00953.1 - 0.046 13.6 3.9 0.15 11.9 0.5 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Fez1 PF06818.10 ETO00953.1 - 0.054 13.5 3.7 0.092 12.7 2.4 1.5 1 1 0 1 1 1 0 Fez1 Cast PF10174.4 ETO00953.1 - 0.063 11.3 5.5 0.079 10.9 3.8 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Baculo_PEP_C PF04513.7 ETO00953.1 - 0.077 12.8 8.8 0.91 9.3 5.1 2.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HemX PF04375.9 ETO00953.1 - 0.088 11.3 3.2 0.17 10.4 0.0 2.1 1 1 1 2 2 2 0 HemX KxDL PF10241.4 ETO00953.1 - 0.091 12.6 0.9 0.19 11.6 0.2 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein DUF1664 PF07889.7 ETO00953.1 - 0.14 11.9 2.0 0.19 11.5 1.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.3 ETO00953.1 - 0.14 11.9 9.6 0.035 13.8 4.3 1.7 2 0 0 2 2 1 0 TATA element modulatory factor 1 DNA binding Nup88 PF10168.4 ETO00953.1 - 0.14 9.9 4.7 0.16 9.7 3.3 1.1 1 0 0 1 1 1 0 Nuclear pore component TBPIP PF07106.8 ETO00953.1 - 0.15 11.6 7.1 0.031 13.8 2.6 1.6 2 0 0 2 2 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GAS PF13851.1 ETO00953.1 - 0.15 11.2 7.4 0.28 10.3 5.0 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF342 PF03961.8 ETO00953.1 - 0.26 9.6 4.9 0.28 9.5 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 ETO00953.1 - 0.28 10.7 7.5 0.33 10.5 5.2 1.3 1 1 0 1 1 1 0 IncA protein MitMem_reg PF13012.1 ETO00953.1 - 0.31 11.1 4.4 0.38 10.8 2.6 1.6 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function V_ATPase_I PF01496.14 ETO00953.1 - 0.32 8.8 3.6 0.34 8.7 2.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.17 ETO00953.1 - 0.46 10.5 6.6 0.31 11.0 2.1 2.3 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Occludin_ELL PF07303.8 ETO00953.1 - 0.46 11.2 4.3 0.28 11.9 1.0 2.1 2 1 0 2 2 1 0 Occludin homology domain Fib_alpha PF08702.5 ETO00953.1 - 0.6 10.2 7.0 0.33 11.0 1.9 2.3 2 1 1 3 3 2 0 Fibrinogen alpha/beta chain family DUF972 PF06156.8 ETO00953.1 - 0.7 10.2 7.7 0.36 11.1 3.6 1.9 2 1 0 2 2 1 0 Protein of unknown function (DUF972) HR1 PF02185.11 ETO00953.1 - 0.88 9.3 9.9 13 5.6 0.2 3.3 1 1 2 3 3 3 0 Hr1 repeat Rho_Binding PF08912.6 ETO00953.1 - 0.9 9.8 11.3 0.095 13.0 0.8 3.0 2 1 2 4 4 3 0 Rho Binding L27_N PF09060.5 ETO00953.1 - 1.2 9.0 3.5 1.5 8.6 0.5 2.2 2 0 0 2 2 2 0 L27_N DUF4208 PF13907.1 ETO00953.1 - 1.4 9.1 4.8 1.7 8.9 1.5 2.2 2 1 0 2 2 1 0 Domain of unknown function (DUF4208) FlgN PF05130.7 ETO00953.1 - 2.1 8.5 8.4 6.7 6.9 5.8 1.8 1 1 0 1 1 1 0 FlgN protein Cortex-I_coil PF09304.5 ETO00953.1 - 2.3 8.3 6.8 3.6 7.6 3.4 2.2 1 1 1 2 2 2 0 Cortexillin I, coiled coil DUF948 PF06103.6 ETO00953.1 - 2.4 8.1 5.9 1.4 8.8 1.7 2.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Prefoldin PF02996.12 ETO00953.1 - 2.4 7.8 8.8 0.92 9.1 0.6 2.5 2 1 2 4 4 3 0 Prefoldin subunit FlaC_arch PF05377.6 ETO00953.1 - 3 7.7 6.0 12 5.8 1.1 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.15 ETO00953.1 - 3.1 7.6 11.9 0.41 10.4 0.8 2.7 2 1 1 3 3 3 0 Prefoldin subunit PRCC PF10253.4 ETO00954.1 - 0.014 16.1 3.0 0.023 15.4 2.1 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting UAE_UbL PF14732.1 ETO00954.1 - 0.058 13.4 0.2 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Lipoprotein_9 PF03180.9 ETO00956.1 - 0.0076 15.1 0.3 0.0087 14.9 0.2 1.1 1 0 0 1 1 1 1 NLPA lipoprotein 7TM_GPCR_Srz PF10325.4 ETO00956.1 - 0.035 13.2 0.3 0.039 13.0 0.2 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srz UPF0181 PF03701.9 ETO00957.1 - 0.0071 15.6 0.6 0.034 13.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0181) bZIP_2 PF07716.10 ETO00957.1 - 0.15 11.8 0.7 0.15 11.8 0.5 3.5 3 1 0 3 3 3 0 Basic region leucine zipper Cep57_CLD_2 PF14197.1 ETO00957.1 - 0.74 9.7 15.5 0.91 9.5 5.6 2.5 1 1 0 2 2 2 0 Centrosome localisation domain of PPC89 FCH PF00611.18 ETO00957.1 - 1 9.5 6.1 2.9 8.1 4.2 1.9 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain DUF883 PF05957.8 ETO00957.1 - 1.7 9.0 5.8 1.2 9.5 1.0 2.5 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) UPF0242 PF06785.6 ETO00957.1 - 1.9 7.0 9.7 2.1 6.9 6.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Surfac_D-trimer PF09006.6 ETO00957.1 - 2.1 8.1 6.5 0.85 9.3 0.2 2.6 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation P4Ha_N PF08336.6 ETO00957.1 - 3.7 7.3 7.6 7.6 6.3 5.3 1.7 1 1 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF342 PF03961.8 ETO00957.1 - 4.7 5.5 9.0 5.5 5.2 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF972 PF06156.8 ETO00957.1 - 7.1 7.0 13.7 11 6.4 5.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) eIF3_N PF09440.5 ETO00957.1 - 7.4 6.7 9.3 4.3 7.5 3.7 1.9 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain AAA_22 PF13401.1 ETO00958.1 - 0.017 15.2 0.0 0.24 11.5 0.0 3.1 3 1 0 3 3 3 0 AAA domain AAA PF00004.24 ETO00958.1 - 0.042 14.0 0.4 0.27 11.4 0.0 2.7 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Med4 PF10018.4 ETO00959.1 - 0.022 14.1 2.9 0.027 13.8 2.0 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Tropomyosin_1 PF12718.2 ETO00959.1 - 0.03 14.1 9.7 0.037 13.8 6.7 1.2 1 0 0 1 1 1 0 Tropomyosin like Lebercilin PF15619.1 ETO00959.1 - 0.031 13.7 6.5 0.037 13.4 4.5 1.1 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Taxilin PF09728.4 ETO00959.1 - 0.031 13.3 7.7 0.036 13.1 5.3 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein TSKS PF15358.1 ETO00959.1 - 0.037 12.1 2.7 0.037 12.2 1.8 1.0 1 0 0 1 1 1 0 Testis-specific serine kinase substrate AAA_13 PF13166.1 ETO00959.1 - 0.082 11.3 5.8 0.096 11.1 4.1 1.0 1 0 0 1 1 1 0 AAA domain Striatin PF08232.7 ETO00959.1 - 0.2 11.9 6.9 0.22 11.8 4.8 1.1 1 0 0 1 1 1 0 Striatin family TBPIP PF07106.8 ETO00959.1 - 0.4 10.2 7.0 0.44 10.0 4.9 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CPSF73-100_C PF11718.3 ETO00959.1 - 0.53 9.6 4.9 0.6 9.4 3.4 1.0 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term ADIP PF11559.3 ETO00959.1 - 0.63 9.9 7.1 0.77 9.6 4.9 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 ETO00959.1 - 1.4 8.5 5.2 1.4 8.5 3.6 1.1 1 0 0 1 1 1 0 IncA protein zf-C4pol PF14260.1 ETO00959.1 - 2.2 8.3 5.2 1.6 8.8 0.2 2.1 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Sugarporin_N PF11471.3 ETO00959.1 - 9.6 5.9 7.3 1.9 8.2 2.6 1.7 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension DUF502 PF04367.8 ETO00960.1 - 0.0099 15.6 0.0 0.72 9.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF502) DUF1548 PF07579.6 ETO00961.1 - 6.4e-05 23.0 4.6 6.4e-05 23.0 3.2 4.3 3 0 0 3 3 3 1 Domain of Unknown Function (DUF1548) DUF1048 PF06304.6 ETO00961.1 - 0.00033 20.9 0.1 0.0014 18.9 0.1 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1048) TMF_DNA_bd PF12329.3 ETO00962.1 - 1.4e-05 24.7 139.2 0.12 12.1 11.9 8.8 1 1 8 9 9 9 7 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 ETO00962.1 - 3.1e-05 23.3 24.4 0.0037 16.4 1.3 4.0 1 1 3 4 4 4 3 Reovirus sigma C capsid protein CENP-Q PF13094.1 ETO00962.1 - 0.013 15.4 14.1 0.013 15.4 9.8 5.4 1 1 3 4 4 4 0 CENP-Q, a CENPA-CAD centromere complex subunit SRP1_TIP1 PF00660.12 ETO00962.1 - 0.031 14.0 8.0 12 5.8 0.1 3.7 3 0 0 3 3 3 0 Seripauperin and TIP1 family APG6 PF04111.7 ETO00962.1 - 0.18 10.7 125.8 0.097 11.7 18.0 5.0 1 1 4 5 5 5 0 Autophagy protein Apg6 CCDC155 PF14662.1 ETO00962.1 - 0.54 9.8 119.1 14 5.2 23.0 4.9 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 NACHT PF05729.7 ETO00966.1 - 0.0075 15.9 0.0 0.019 14.6 0.0 1.6 1 1 0 1 1 1 1 NACHT domain Parvo_coat_N PF08398.5 ETO00966.1 - 0.26 11.1 1.1 0.49 10.2 0.8 1.5 1 0 0 1 1 1 0 Parvovirus coat protein VP1 Reo_sigmaC PF04582.7 ETO00967.1 - 0.00087 18.5 2.9 0.00087 18.5 2.0 4.1 1 1 2 4 4 4 2 Reovirus sigma C capsid protein Kinetocho_Slk19 PF12709.2 ETO00967.1 - 0.0076 16.3 7.7 0.0076 16.3 5.3 7.6 4 1 4 8 8 8 1 Central kinetochore-associated Filament PF00038.16 ETO00967.1 - 0.82 9.0 80.0 0.02 14.3 7.5 3.8 1 1 0 2 2 2 0 Intermediate filament protein IncA PF04156.9 ETO00967.1 - 7.8 6.0 86.1 2.5 7.6 16.1 5.2 1 1 5 6 6 6 0 IncA protein VWA PF00092.23 ETO00968.1 - 0.0014 18.3 2.4 0.0034 17.1 1.6 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain HD_3 PF13023.1 ETO00968.1 - 0.014 15.1 0.6 0.014 15.1 0.4 2.6 3 1 0 3 3 3 0 HD domain DUF4354 PF14263.1 ETO00968.1 - 0.015 14.9 1.0 0.053 13.2 0.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4354) BLVR PF06375.6 ETO00969.1 - 0.13 12.0 1.9 0.7 9.7 0.1 2.0 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) MHC_II_beta PF00969.14 ETO00970.1 - 0.016 15.1 0.1 0.95 9.4 0.0 3.1 3 0 0 3 3 3 0 Class II histocompatibility antigen, beta domain Alliinase_C PF04864.8 ETO00970.1 - 0.039 12.5 0.4 0.26 9.8 0.3 2.0 1 1 0 1 1 1 0 Allinase DUF4363 PF14276.1 ETO00970.1 - 0.074 12.7 0.4 0.074 12.7 0.2 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) Neuropep_like PF15161.1 ETO00970.1 - 0.12 11.8 0.0 0.71 9.3 0.0 2.2 2 0 0 2 2 2 0 Neuropeptide-like Nbl1_Borealin_N PF10444.4 ETO00970.1 - 0.38 10.1 2.8 1.3 8.4 0.3 2.7 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal DUF2433 PF10360.4 ETO00971.1 - 0.039 14.2 0.4 0.052 13.8 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2433) Tektin PF03148.9 ETO00971.1 - 0.15 10.5 4.7 0.17 10.4 3.2 1.1 1 0 0 1 1 1 0 Tektin family HALZ PF02183.13 ETO00971.1 - 1.6 8.5 7.4 7.6 6.3 0.5 2.9 2 1 0 2 2 2 0 Homeobox associated leucine zipper DUF830 PF05708.7 ETO00973.1 - 0.13 12.2 1.1 0.17 11.8 0.6 1.3 1 1 0 1 1 1 0 Orthopoxvirus protein of unknown function (DUF830) PRD PF00874.15 ETO00973.1 - 0.61 10.2 2.9 0.79 9.8 0.5 2.1 2 0 0 2 2 2 0 PRD domain VirB3 PF05101.8 ETO00974.1 - 0.073 13.0 0.2 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein DUF2418 PF10332.4 ETO00974.1 - 1.4 9.2 4.3 3.6 7.9 3.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2418) DUF3015 PF11220.3 ETO00975.1 - 0.34 10.4 1.8 3.2 7.3 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3015) Vfa1 PF08432.5 ETO00976.1 - 0.096 12.6 3.9 0.11 12.4 2.7 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop25 PF09805.4 ETO00976.1 - 0.17 11.9 6.5 0.19 11.8 4.5 1.0 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF2722 PF10846.3 ETO00976.1 - 1.8 7.4 9.8 2 7.3 6.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Secretin_N_2 PF07655.8 ETO00976.1 - 2.6 8.4 15.1 3.3 8.1 10.5 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain DUF2362 PF10154.4 ETO00977.1 - 0.0056 15.4 6.2 0.0062 15.2 4.3 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) EcoRI PF02963.11 ETO00977.1 - 0.024 13.4 0.9 0.028 13.2 0.6 1.1 1 0 0 1 1 1 0 Restriction endonuclease EcoRI TRAPPC-Trs85 PF12739.2 ETO00977.1 - 0.073 11.7 1.9 0.095 11.3 1.3 1.1 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit MoCo_carrier PF12694.2 ETO00977.1 - 0.11 11.8 0.5 0.13 11.6 0.3 1.1 1 0 0 1 1 1 0 Putative molybdenum carrier Fra10Ac1 PF09725.4 ETO00979.1 - 0.19 11.7 1.9 0.9 9.6 0.0 2.3 2 1 0 2 2 2 0 Folate-sensitive fragile site protein Fra10Ac1 Pyr_redox_dim PF02852.17 ETO00980.1 - 0.00024 21.0 0.0 0.00049 20.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain DUF3610 PF12272.3 ETO00981.1 - 0.16 11.6 3.4 0.19 11.3 2.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3610) His_Phos_2 PF00328.17 ETO00981.1 - 0.34 10.1 2.4 0.63 9.3 1.6 1.4 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Cupin_4 PF08007.7 ETO00982.1 - 6.5e-18 65.0 0.1 1.6e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.1 ETO00982.1 - 2.8e-09 36.8 0.3 5.9e-09 35.7 0.2 1.8 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 ETO00982.1 - 0.00046 20.4 0.3 0.0026 17.9 0.0 2.4 1 1 1 2 2 2 1 JmjC domain, hydroxylase PAP1 PF08601.5 ETO00982.1 - 0.48 10.0 3.8 0.093 12.3 0.2 1.5 2 0 0 2 2 2 0 Transcription factor PAP1 RNase_H PF00075.19 ETO00983.1 - 2.4e-15 57.0 0.6 3.9e-15 56.3 0.0 1.6 2 0 0 2 2 2 1 RNase H RVT_3 PF13456.1 ETO00983.1 - 0.00025 20.7 0.1 0.00066 19.4 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase-like PBS_linker_poly PF00427.16 ETO00985.1 - 0.072 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide DUF3944 PF13099.1 ETO00985.1 - 0.52 9.8 3.4 1.4 8.5 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3944) WD40 PF00400.27 ETO00986.1 - 0.0084 15.9 0.0 0.47 10.4 0.0 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO00986.1 - 0.017 13.2 0.0 0.017 13.2 0.0 1.0 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Arena_nucleocap PF00843.12 ETO00986.1 - 0.086 10.7 0.0 0.088 10.6 0.0 1.0 1 0 0 1 1 1 0 Arenavirus nucleocapsid protein Mad3_BUB1_I PF08311.7 ETO00987.1 - 0.015 15.0 1.3 0.22 11.2 0.0 2.2 1 1 1 2 2 2 0 Mad3/BUB1 homology region 1 Bromo_MP PF01573.11 ETO00989.1 - 0.045 12.7 4.4 0.053 12.4 3.0 1.0 1 0 0 1 1 1 0 Bromovirus movement protein zf-HC5HC2H PF13771.1 ETO00989.1 - 0.091 12.9 2.5 0.14 12.3 1.7 1.4 1 1 0 1 1 1 0 PHD-like zinc-binding domain FANCL_C PF11793.3 ETO00989.1 - 0.11 12.5 0.5 0.14 12.1 0.3 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain DUF2458 PF10454.4 ETO00989.1 - 0.2 11.5 9.5 1.7 8.4 1.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2458) DUF948 PF06103.6 ETO00989.1 - 0.72 9.7 4.2 11 5.9 0.5 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF515 PF04415.7 ETO00990.1 - 0.24 9.5 2.2 0.26 9.4 1.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) CobT PF06213.7 ETO00990.1 - 0.27 10.3 4.3 0.27 10.3 3.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4611 PF15387.1 ETO00990.1 - 0.49 10.5 3.6 0.43 10.7 1.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) ANAPC15 PF15243.1 ETO00991.1 - 0.16 12.0 11.0 0.054 13.5 2.7 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 PBP1_TM PF14812.1 ETO00991.1 - 1.9 8.8 13.3 0.37 11.1 4.8 2.3 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tubulin_C PF03953.12 ETO00992.1 - 1e-15 57.8 0.2 1.6e-15 57.2 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain FAD_binding_8 PF08022.7 ETO00993.1 - 2.4e-18 65.9 0.0 3.6e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.19 ETO00993.1 - 0.00012 22.0 0.0 0.00018 21.5 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain EF1G PF00647.14 ETO00994.1 - 0.082 12.6 0.1 0.31 10.7 0.0 2.0 2 1 0 2 2 2 0 Elongation factor 1 gamma, conserved domain Ssl1 PF04056.9 ETO00994.1 - 0.11 12.1 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 Ssl1-like Tubulin_C PF03953.12 ETO00995.1 - 3.2e-12 46.6 0.1 4.4e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain FAD_binding_8 PF08022.7 ETO00996.1 - 7.1e-23 80.4 0.0 1.2e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 ETO00996.1 - 7.4e-09 35.7 5.4 1.4e-08 34.8 3.8 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 ETO00996.1 - 7.3e-05 22.8 0.0 0.00018 21.5 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Fork_head PF00250.13 ETO00997.1 - 0.0063 16.5 0.7 0.011 15.7 0.2 1.6 2 0 0 2 2 2 1 Fork head domain DUF221 PF02714.10 ETO00997.1 - 0.022 13.6 0.4 0.033 13.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF221 ComFB PF10719.4 ETO00997.1 - 0.099 12.3 0.2 0.099 12.3 0.1 2.0 2 0 0 2 2 2 0 Late competence development protein ComFB Pox_A31 PF05771.6 ETO00997.1 - 0.24 11.2 7.8 1.1 9.0 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A31 protein WD40 PF00400.27 ETO00998.1 - 9.3e-21 72.8 0.7 5.8e-09 35.4 0.0 2.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO00998.1 - 0.00077 17.7 0.1 0.066 11.3 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO00998.1 - 0.043 12.5 0.3 0.4 9.3 0.0 2.0 1 1 1 2 2 2 0 Nup133 N terminal like USP7_C2 PF14533.1 ETO00998.1 - 0.098 12.0 0.1 0.24 10.8 0.1 1.5 1 1 1 2 2 2 0 Ubiquitin-specific protease C-terminal ComX PF05952.7 ETO00999.1 - 0.022 14.2 0.4 0.11 12.0 0.1 2.3 2 0 0 2 2 2 0 Bacillus competence pheromone ComX Asp_Glu_race_2 PF14669.1 ETO00999.1 - 0.2 10.9 4.7 0.29 10.4 0.1 2.9 4 0 0 4 4 4 0 Putative aspartate racemase AAA_14 PF13173.1 ETO01000.1 - 1.1e-05 25.2 0.2 0.0082 16.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA PF00004.24 ETO01000.1 - 6.5e-05 23.1 0.0 0.0003 20.9 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETO01000.1 - 0.00017 21.3 0.0 0.00057 19.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 ETO01000.1 - 0.00024 21.3 0.6 0.0036 17.6 0.0 2.4 2 0 0 2 2 2 1 ABC transporter DUF815 PF05673.8 ETO01000.1 - 0.00098 18.1 0.0 0.0018 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DUF258 PF03193.11 ETO01000.1 - 0.0012 18.0 0.0 0.0026 16.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 ETO01000.1 - 0.002 18.2 0.1 0.019 15.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain DDE_Tnp_1_7 PF13843.1 ETO01000.1 - 0.016 14.2 0.9 0.036 13.1 0.2 1.8 2 0 0 2 2 2 0 Transposase IS4 MCM PF00493.18 ETO01000.1 - 0.019 13.7 0.1 0.12 11.1 0.0 2.1 2 0 0 2 2 2 0 MCM2/3/5 family Sigma54_activ_2 PF14532.1 ETO01000.1 - 0.034 14.1 0.0 0.2 11.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 ETO01000.1 - 0.074 12.5 0.0 0.19 11.1 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.9 ETO01002.1 - 0.00067 19.3 0.0 0.0015 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF258 PF03193.11 ETO01002.1 - 0.00074 18.7 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 DUF815 PF05673.8 ETO01002.1 - 0.00082 18.3 0.0 0.0013 17.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 ETO01002.1 - 0.00085 19.6 0.8 0.0022 18.2 0.0 1.9 2 1 0 2 2 2 1 ABC transporter AAA PF00004.24 ETO01002.1 - 0.00087 19.4 0.0 0.0022 18.1 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETO01002.1 - 0.0021 18.1 0.3 0.012 15.7 0.0 2.2 2 1 1 3 3 3 1 AAA domain MCM PF00493.18 ETO01002.1 - 0.036 12.8 0.0 0.071 11.9 0.0 1.5 1 1 0 1 1 1 0 MCM2/3/5 family Sigma54_activ_2 PF14532.1 ETO01002.1 - 0.058 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 ETO01002.1 - 0.059 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.1 ETO01002.1 - 0.63 10.3 0.1 0.63 10.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain Tubulin_C PF03953.12 ETO01003.1 - 5e-05 23.3 0.1 6e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Tubulin C-terminal domain Pkinase PF00069.20 ETO01004.1 - 9.6e-45 152.7 0.0 1.2e-44 152.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO01004.1 - 2.2e-22 79.4 0.0 2.6e-22 79.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO01004.1 - 0.00021 20.3 0.0 0.00027 20.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETO01004.1 - 0.0045 16.7 0.1 0.03 14.0 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 ETO01004.1 - 0.0087 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 ETO01004.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Guanylate_cyc PF00211.15 ETO01006.1 - 8.6e-09 35.0 0.3 1.3e-08 34.4 0.2 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF1823 PF08853.6 ETO01006.1 - 0.044 13.5 0.2 0.075 12.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1823) CEP44 PF15007.1 ETO01006.1 - 0.56 9.9 8.1 0.086 12.5 2.2 2.2 2 1 0 2 2 2 0 Centrosomal spindle body, CEP44 GlcNAc PF11397.3 ETO01007.1 - 1.2e-36 126.5 0.0 1.3e-36 126.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) TPR_11 PF13414.1 ETO01008.1 - 2.7e-06 26.9 1.7 1.1e-05 25.0 0.2 2.1 1 1 1 2 2 2 1 TPR repeat TPR_1 PF00515.23 ETO01008.1 - 0.00011 21.6 0.1 0.00045 19.7 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO01008.1 - 0.00018 21.4 2.7 0.00079 19.4 0.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO01008.1 - 0.002 17.8 0.0 0.0071 16.1 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF482 PF04339.7 ETO01008.1 - 0.0024 16.8 0.4 0.0035 16.2 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF482 TPR_8 PF13181.1 ETO01008.1 - 0.031 14.0 2.0 0.052 13.3 0.1 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DDHD PF02862.12 ETO01009.1 - 0.28 10.9 1.7 0.32 10.7 1.2 1.1 1 0 0 1 1 1 0 DDHD domain UPF0121 PF03661.8 ETO01010.1 - 0.032 13.4 0.0 0.035 13.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0121) Imm7 PF15588.1 ETO01012.1 - 0.025 14.6 4.4 0.088 12.8 3.0 2.1 1 1 0 1 1 1 0 Immunity protein 7 Spc7 PF08317.6 ETO01012.1 - 0.1 11.2 21.2 0.11 11.1 14.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FlxA PF14282.1 ETO01012.1 - 0.57 10.1 33.1 0.076 12.9 19.8 1.7 1 1 0 1 1 1 0 FlxA-like protein DUF342 PF03961.8 ETO01012.1 - 1.1 7.5 17.2 1.6 7.0 11.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4239 PF14023.1 ETO01012.1 - 2.3 7.5 4.8 2.6 7.3 3.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) VWD PF00094.20 ETO01012.1 - 2.3 8.3 12.3 0.37 10.9 2.1 2.0 1 1 1 2 2 2 0 von Willebrand factor type D domain B56 PF01603.15 ETO01013.1 - 5.5e-39 133.9 1.6 6.3e-39 133.7 1.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) B56 PF01603.15 ETO01014.1 - 0.0054 15.3 0.7 0.02 13.4 0.0 1.8 1 1 1 2 2 2 1 Protein phosphatase 2A regulatory B subunit (B56 family) Spore_III_AB PF09548.5 ETO01014.1 - 0.1 12.3 0.4 0.14 11.9 0.3 1.3 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) B56 PF01603.15 ETO01015.1 - 3e-10 39.2 3.6 4.4e-10 38.7 2.5 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Menin PF05053.8 ETO01015.1 - 0.0056 14.9 14.1 0.0069 14.6 9.8 1.1 1 0 0 1 1 1 1 Menin Daxx PF03344.10 ETO01015.1 - 0.0083 14.6 20.9 0.01 14.3 14.5 1.0 1 0 0 1 1 1 1 Daxx Family CDC45 PF02724.9 ETO01015.1 - 1.4 6.8 15.9 2.1 6.3 11.0 1.4 1 0 0 1 1 1 0 CDC45-like protein Atrophin-1 PF03154.10 ETO01015.1 - 1.5 6.8 10.4 1.8 6.6 7.2 1.1 1 0 0 1 1 1 0 Atrophin-1 family Hid1 PF12722.2 ETO01015.1 - 2.5 5.6 17.3 2.8 5.5 12.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.11 ETO01015.1 - 4.1 7.2 10.1 7.4 6.3 7.0 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S64 PF08192.6 ETO01015.1 - 5.7 5.1 16.3 7.1 4.8 11.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 Utp14 PF04615.8 ETO01015.1 - 7.9 4.5 27.7 10 4.1 19.2 1.1 1 0 0 1 1 1 0 Utp14 protein B56 PF01603.15 ETO01016.1 - 1.4e-43 149.1 6.1 1.5e-43 148.9 4.3 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Herpes_glycop PF01528.11 ETO01017.1 - 0.00013 20.7 0.0 0.00019 20.2 0.0 1.2 1 0 0 1 1 1 1 Herpesvirus glycoprotein M Protocadherin PF08374.6 ETO01017.1 - 0.0017 18.0 0.7 0.0038 16.9 0.5 1.6 1 0 0 1 1 1 1 Protocadherin Rifin_STEVOR PF02009.11 ETO01017.1 - 0.0041 16.8 0.8 0.0041 16.8 0.6 2.0 2 0 0 2 2 2 1 Rifin/stevor family Foamy_virus_ENV PF03408.9 ETO01017.1 - 0.005 14.4 1.1 0.0067 14.0 0.8 1.1 1 0 0 1 1 1 1 Foamy virus envelope protein OAD_gamma PF04277.8 ETO01017.1 - 0.0057 17.0 1.3 0.081 13.3 0.0 2.5 2 0 0 2 2 2 1 Oxaloacetate decarboxylase, gamma chain DUF1183 PF06682.7 ETO01017.1 - 0.075 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) MSC PF09402.5 ETO01017.1 - 0.16 10.6 1.9 0.38 9.4 1.3 1.6 1 1 0 1 1 1 0 Man1-Src1p-C-terminal domain EphA2_TM PF14575.1 ETO01017.1 - 0.23 11.8 1.5 0.37 11.2 0.2 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 ETO01017.1 - 0.67 9.6 8.5 2.5 7.8 5.9 2.0 1 1 0 1 1 1 0 TMEM154 protein family ASFV_J13L PF05568.6 ETO01017.1 - 1.6 8.2 9.2 3.1 7.2 6.4 1.5 1 1 0 1 1 1 0 African swine fever virus J13L protein Phlebovirus_G2 PF07245.6 ETO01017.1 - 2.2 6.4 4.3 3.3 5.8 3.0 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G2 Shisa PF13908.1 ETO01017.1 - 5 7.2 9.5 0.55 10.3 3.4 1.7 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF1510 PF07423.6 ETO01017.1 - 6.7 6.0 10.9 0.043 13.1 0.5 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) DUF399 PF04187.8 ETO01018.1 - 0.0036 16.8 0.1 0.023 14.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF399 Glyco_transf_49 PF13896.1 ETO01019.1 - 2.7e-12 46.4 0.1 4.9e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 ETO01019.1 - 0.00026 20.1 0.5 0.0019 17.3 0.0 2.4 2 1 0 3 3 3 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 ETO01019.1 - 0.00039 20.1 0.1 0.0014 18.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Ldh_1_N PF00056.18 ETO01020.1 - 0.00028 20.7 0.0 0.00035 20.4 0.0 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Kelch_4 PF13418.1 ETO01021.1 - 0.0003 20.5 0.1 0.001 18.7 0.0 1.8 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO01021.1 - 0.003 17.0 0.9 0.23 11.0 0.2 2.4 2 0 0 2 2 2 2 Kelch motif Ham1p_like PF01725.11 ETO01021.1 - 0.13 11.5 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Ham1 family SecY PF00344.15 ETO01022.1 - 4.8e-48 163.8 3.9 4.8e-48 163.8 2.7 1.7 2 0 0 2 2 2 1 SecY translocase FAA_hydrolase PF01557.13 ETO01024.1 - 1.2e-45 155.6 0.0 1.9e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family UN_NPL4 PF11543.3 ETO01026.1 - 0.12 12.6 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 HisKA_2 PF07568.7 ETO01027.1 - 0.027 14.3 0.2 0.048 13.5 0.1 1.4 1 0 0 1 1 1 0 Histidine kinase APG5 PF04106.7 ETO01027.1 - 0.098 12.1 1.3 0.12 11.8 0.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg5 Ank_2 PF12796.2 ETO01028.1 - 0.00085 19.6 0.1 0.0024 18.1 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO01028.1 - 0.0058 17.1 0.1 0.079 13.4 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) EspA PF03433.8 ETO01028.1 - 0.035 13.5 0.1 0.051 13.0 0.1 1.2 1 0 0 1 1 1 0 EspA-like secreted protein S6PP PF05116.8 ETO01028.1 - 0.046 13.0 0.0 0.069 12.4 0.0 1.5 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase DHC PF09626.5 ETO01028.1 - 0.094 13.3 0.3 0.25 11.9 0.0 1.8 2 0 0 2 2 2 0 Dihaem cytochrome c Tubulin_C PF03953.12 ETO01030.1 - 4.4e-25 88.1 0.0 6.7e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Peptidase_S76 PF13611.1 ETO01031.1 - 0.23 11.5 2.8 8 6.6 0.2 2.7 2 1 1 3 3 3 0 Serine peptidase of plant viral polyprotein, P1 Tubulin_C PF03953.12 ETO01032.1 - 6.5e-23 81.1 0.1 3.9e-22 78.6 0.0 1.9 1 1 0 1 1 1 1 Tubulin C-terminal domain PBP-Tp47_a PF14889.1 ETO01032.1 - 0.046 13.0 0.0 0.063 12.5 0.0 1.2 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain a HEAT_2 PF13646.1 ETO01034.1 - 1.6e-07 31.4 0.0 5.1e-05 23.4 0.0 2.6 1 1 2 3 3 3 2 HEAT repeats HEAT PF02985.17 ETO01034.1 - 4.6e-07 29.3 0.0 0.0003 20.5 0.0 4.1 5 0 0 5 5 5 1 HEAT repeat ENTH PF01417.15 ETO01034.1 - 2.4e-06 27.4 1.0 0.051 13.4 0.0 3.6 1 1 2 4 4 4 2 ENTH domain Cnd1 PF12717.2 ETO01034.1 - 6.6e-06 26.0 4.2 0.0067 16.2 0.7 2.9 1 1 2 3 3 3 3 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 ETO01034.1 - 0.00019 20.8 3.1 0.013 14.8 0.2 2.6 1 1 1 2 2 2 2 CLASP N terminal HEAT_EZ PF13513.1 ETO01034.1 - 0.00031 21.1 0.0 0.024 15.1 0.0 3.3 3 1 1 4 4 3 1 HEAT-like repeat UME PF08064.8 ETO01034.1 - 0.0017 18.2 0.2 0.053 13.4 0.0 2.7 2 1 0 2 2 2 1 UME (NUC010) domain MOR2-PAG1_N PF14222.1 ETO01034.1 - 0.0017 17.1 0.0 0.58 8.7 0.0 2.3 1 1 1 2 2 2 2 Cell morphogenesis N-terminal TIP120 PF08623.5 ETO01034.1 - 0.0027 17.2 3.5 0.06 12.9 0.1 2.6 1 1 2 3 3 3 1 TATA-binding protein interacting (TIP20) DUF2608 PF11019.3 ETO01034.1 - 0.0028 16.6 0.5 1 8.3 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2608) DUF2435 PF10363.4 ETO01034.1 - 0.014 15.3 0.7 17 5.3 0.1 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF2435) DUF2758 PF10957.3 ETO01034.1 - 0.017 14.9 0.8 14 5.6 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2758) DUF3554 PF12074.3 ETO01034.1 - 0.025 14.0 0.5 0.08 12.3 0.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3554) AAR2 PF05282.6 ETO01034.1 - 0.029 13.3 0.5 0.029 13.3 0.3 1.5 2 0 0 2 2 2 0 AAR2 protein Closter_coat PF01785.12 ETO01034.1 - 0.037 13.0 2.1 4.3 6.3 0.0 2.9 2 1 1 3 3 3 0 Closterovirus coat protein Vac14_Fab1_bd PF12755.2 ETO01034.1 - 0.068 13.5 0.5 0.95 9.8 0.0 2.6 1 1 2 3 3 3 0 Vacuolar 14 Fab1-binding region MH1 PF03165.11 ETO01034.1 - 0.29 11.1 6.0 3.6 7.6 0.1 3.3 2 1 0 2 2 2 0 MH1 domain NLE PF08154.7 ETO01034.1 - 1.9 8.5 6.1 8.8 6.4 0.0 3.8 6 0 0 6 6 5 0 NLE (NUC135) domain WD40 PF00400.27 ETO01035.1 - 6.6e-44 146.2 19.6 6.9e-11 41.5 0.0 6.2 5 1 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO01035.1 - 3.9e-05 22.0 2.2 0.62 8.1 0.4 3.7 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DEP PF00610.16 ETO01036.1 - 1.2e-15 57.0 0.2 1.5e-15 56.6 0.2 1.1 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) EF-hand_1 PF00036.27 ETO01037.1 - 0.0015 17.7 0.0 0.0029 16.8 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 ETO01037.1 - 0.0079 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 ETO01037.1 - 0.011 15.0 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.1 ETO01037.1 - 0.011 15.7 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair Mt_ATP-synt_B PF05405.9 ETO01037.1 - 0.027 13.9 0.5 0.042 13.3 0.3 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Tropomyosin_1 PF12718.2 ETO01038.1 - 9.4e-05 22.2 48.5 0.0021 17.9 4.6 3.2 1 1 2 3 3 3 2 Tropomyosin like HOOK PF05622.7 ETO01038.1 - 0.0001 20.3 41.3 0.00011 20.2 24.1 2.3 1 1 1 2 2 2 1 HOOK protein IncA PF04156.9 ETO01038.1 - 0.00019 21.0 41.0 0.011 15.3 12.9 3.1 1 1 2 3 3 3 3 IncA protein Fib_alpha PF08702.5 ETO01038.1 - 0.0061 16.7 16.1 0.0061 16.7 11.2 3.0 1 1 2 3 3 3 2 Fibrinogen alpha/beta chain family Phage_GP20 PF06810.6 ETO01038.1 - 0.015 14.7 16.5 0.015 14.7 11.4 3.2 1 1 2 3 3 3 0 Phage minor structural protein GP20 APG6 PF04111.7 ETO01038.1 - 0.017 14.1 45.0 0.25 10.3 14.2 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 Mnd1 PF03962.10 ETO01038.1 - 0.024 14.3 41.3 0.26 10.9 8.0 3.1 1 1 2 3 3 3 0 Mnd1 family GAS PF13851.1 ETO01038.1 - 0.057 12.6 49.4 0.33 10.0 15.0 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 ETO01038.1 - 0.078 12.1 6.8 0.34 10.0 0.9 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Laminin_I PF06008.9 ETO01038.1 - 0.2 10.9 35.1 9.3 5.4 24.3 2.2 1 1 0 1 1 1 0 Laminin Domain I Filament PF00038.16 ETO01038.1 - 0.22 10.9 38.6 1.1 8.6 26.8 2.0 1 1 0 1 1 1 0 Intermediate filament protein Tropomyosin PF00261.15 ETO01038.1 - 0.28 10.2 36.4 0.16 11.0 10.1 2.3 1 1 1 2 2 2 0 Tropomyosin Seryl_tRNA_N PF02403.17 ETO01038.1 - 0.62 10.1 46.4 0.049 13.6 3.4 3.7 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF4613 PF15390.1 ETO01038.1 - 0.62 8.1 22.0 0.76 7.8 15.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) AAA_13 PF13166.1 ETO01038.1 - 0.64 8.4 48.7 0.17 10.2 20.8 2.5 1 1 1 2 2 2 0 AAA domain Pox_A_type_inc PF04508.7 ETO01038.1 - 0.71 9.8 0.1 0.71 9.8 0.1 5.3 6 1 1 7 7 6 0 Viral A-type inclusion protein repeat CENP-F_leu_zip PF10473.4 ETO01038.1 - 0.84 9.4 41.1 1.2 8.9 11.9 2.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.6 ETO01038.1 - 1.2 7.7 45.2 0.8 8.2 19.3 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF812 PF05667.6 ETO01038.1 - 1.4 7.3 37.5 1.4 7.3 13.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) CCDC155 PF14662.1 ETO01038.1 - 1.6 8.3 42.1 0.041 13.4 16.9 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 TMF_DNA_bd PF12329.3 ETO01038.1 - 4 7.3 57.5 0.19 11.5 11.0 4.1 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding ACT_5 PF13710.1 ETO01038.1 - 4 7.3 5.7 15 5.4 0.1 3.0 3 0 0 3 3 3 0 ACT domain MCPsignal PF00015.16 ETO01038.1 - 6.2 6.2 16.2 4.2 6.8 3.2 2.6 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Mod_r PF07200.8 ETO01038.1 - 6.9 6.5 39.2 2.3 8.1 13.1 2.7 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Prefoldin_2 PF01920.15 ETO01038.1 - 7.8 6.3 50.9 0.25 11.1 7.4 5.3 1 1 5 6 6 6 0 Prefoldin subunit Rab5-bind PF09311.6 ETO01038.1 - 8.8 6.1 35.1 1.1 9.0 19.1 2.4 1 1 1 2 2 2 0 Rabaptin-like protein Transposase_22 PF02994.9 ETO01038.1 - 9.7 4.5 34.9 10 4.5 11.4 2.3 1 1 1 2 2 2 0 L1 transposable element HHV6-IE PF03753.8 ETO01039.1 - 0.23 8.8 6.4 0.28 8.6 4.5 1.0 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein ATHILA PF03078.10 ETO01039.1 - 2.9 6.3 6.0 3.9 5.9 4.2 1.1 1 0 0 1 1 1 0 ATHILA ORF-1 family Tubulin PF00091.20 ETO01040.1 - 6.7e-09 35.8 0.0 9e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Herpes_VP19C PF03327.9 ETO01040.1 - 0.051 12.4 0.0 0.067 12.0 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus capsid shell protein VP19C NapE PF06796.6 ETO01040.1 - 0.095 12.0 0.1 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE TPR_12 PF13424.1 ETO01041.1 - 5.5e-89 292.1 26.1 3e-26 91.1 1.7 4.1 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO01041.1 - 4.6e-62 204.3 0.0 1e-08 34.8 0.0 7.0 6 1 1 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.23 ETO01041.1 - 2.8e-61 200.7 47.3 1e-10 40.7 0.4 7.1 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.1 ETO01041.1 - 3.8e-56 182.5 17.8 2.2e-08 33.2 0.0 7.1 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_2 PF07719.12 ETO01041.1 - 1.7e-51 167.9 34.9 2.8e-08 33.0 0.1 7.2 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_11 PF13414.1 ETO01041.1 - 5e-49 163.8 29.8 1.1e-17 63.3 1.4 5.2 3 1 1 5 5 5 5 TPR repeat TPR_8 PF13181.1 ETO01041.1 - 5.2e-47 154.1 59.8 8.1e-09 34.6 0.9 7.1 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_17 PF13431.1 ETO01041.1 - 1.4e-24 84.1 22.6 8.5e-05 22.4 0.0 7.8 8 2 0 8 8 6 6 Tetratricopeptide repeat TPR_16 PF13432.1 ETO01041.1 - 1.1e-22 80.0 2.5 3.4e-06 27.5 0.1 5.6 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO01041.1 - 2.9e-22 77.1 0.0 0.044 14.4 0.0 7.0 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.1 ETO01041.1 - 2.4e-21 74.6 13.7 0.0035 17.7 0.1 7.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_3 PF07720.7 ETO01041.1 - 2.1e-16 59.3 30.6 0.0059 16.3 0.1 7.1 7 0 0 7 7 7 6 Tetratricopeptide repeat Sel1 PF08238.7 ETO01041.1 - 6.8e-14 51.9 23.9 0.064 13.9 0.1 7.4 7 0 0 7 7 7 5 Sel1 repeat SHNi-TPR PF10516.4 ETO01041.1 - 5.5e-13 47.9 6.0 0.79 9.0 0.0 7.2 7 0 0 7 7 7 4 SHNi-TPR TPR_19 PF14559.1 ETO01041.1 - 1.6e-11 44.3 9.3 0.0053 17.0 0.3 5.0 2 2 4 6 6 6 5 Tetratricopeptide repeat Apc3 PF12895.2 ETO01041.1 - 2.6e-11 43.5 28.7 7.3e-06 26.0 4.9 4.8 1 1 4 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 ETO01041.1 - 1.9e-10 40.4 36.0 0.029 14.2 0.5 7.1 6 1 1 7 7 7 5 MIT (microtubule interacting and transport) domain PPR PF01535.15 ETO01041.1 - 4.7e-10 38.7 18.1 0.14 12.1 0.1 6.5 7 0 0 7 7 6 2 PPR repeat TPR_9 PF13371.1 ETO01041.1 - 1e-08 34.9 0.0 0.046 13.5 0.0 4.6 3 2 0 4 4 4 2 Tetratricopeptide repeat Mob_Pre PF01076.14 ETO01041.1 - 2.1e-07 30.7 15.1 1.4e-05 24.7 1.3 3.9 1 1 3 4 4 4 2 Plasmid recombination enzyme DUF2225 PF09986.4 ETO01041.1 - 1.1e-06 28.3 19.7 0.13 11.6 4.3 4.2 1 1 2 3 3 3 3 Uncharacterized protein conserved in bacteria (DUF2225) ATP-synt_E_2 PF08112.6 ETO01041.1 - 2.7e-06 27.3 26.3 2.5 8.2 0.3 7.2 7 0 0 7 7 7 3 ATP synthase epsilon subunit RPN7 PF10602.4 ETO01041.1 - 0.00012 21.4 23.5 0.11 11.8 2.8 4.7 1 1 3 5 5 5 3 26S proteasome subunit RPN7 Musclin PF11037.3 ETO01041.1 - 0.0002 20.9 0.1 23 4.6 0.0 5.5 6 1 1 7 7 7 0 Insulin-resistance promoting peptide in skeletal muscle DUF3568 PF12092.3 ETO01041.1 - 0.00025 20.7 1.5 0.095 12.4 0.1 3.8 1 1 3 4 4 4 1 Protein of unknown function (DUF3568) DUF3856 PF12968.2 ETO01041.1 - 0.032 14.0 5.2 1.3 8.8 0.1 3.7 1 1 3 4 4 4 0 Domain of Unknown Function (DUF3856) NHL PF01436.16 ETO01041.1 - 0.042 13.8 3.5 0.31 11.0 0.1 3.4 3 0 0 3 3 3 0 NHL repeat Fis1_TPR_C PF14853.1 ETO01041.1 - 0.062 13.1 1.3 0.062 13.1 0.9 6.4 7 0 0 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat DUF4159 PF13709.1 ETO01041.1 - 0.069 12.2 0.4 0.58 9.2 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4159) mRNA_cap_C PF03919.10 ETO01041.1 - 0.13 12.6 2.4 6.4 7.1 0.0 3.8 3 1 0 4 4 3 0 mRNA capping enzyme, C-terminal domain DLD PF14878.1 ETO01041.1 - 0.19 11.8 8.1 23 5.1 0.2 4.6 1 1 4 5 5 5 0 Death-like domain of SPT6 PPR_2 PF13041.1 ETO01041.1 - 0.45 10.5 11.9 53 3.8 0.0 5.7 6 0 0 6 6 6 0 PPR repeat family Ribosomal_S7 PF00177.16 ETO01041.1 - 0.62 9.6 3.3 41 3.7 0.0 3.7 2 1 0 4 4 4 0 Ribosomal protein S7p/S5e Ubiq-assoc PF09145.5 ETO01041.1 - 0.69 9.8 35.7 8.4 6.3 0.2 8.9 6 3 4 10 10 10 0 Ubiquitin-associated OEP PF02321.13 ETO01041.1 - 9.2 5.8 10.3 13 5.3 0.3 3.5 2 2 2 4 4 4 0 Outer membrane efflux protein PP1c_bdg PF10488.4 ETO01043.1 - 6.1 5.9 19.8 11 5.1 13.7 1.4 1 0 0 1 1 1 0 Phosphatase-1 catalytic subunit binding region Ret_tiss PF10044.4 ETO01046.1 - 8.3 7.0 9.4 7.2 7.2 0.2 3.7 1 1 3 4 4 4 0 Retinal tissue protein Peptidase_M8 PF01457.11 ETO01047.1 - 0.21 9.9 1.9 0.2 9.9 1.3 1.0 1 0 0 1 1 1 0 Leishmanolysin Kinesin PF00225.18 ETO01049.1 - 1e-10 40.8 0.7 1.6e-10 40.2 0.5 1.2 1 0 0 1 1 1 1 Kinesin motor domain CAMSAP_CH PF11971.3 ETO01049.1 - 0.29 10.8 3.3 0.37 10.4 0.1 2.5 1 1 2 3 3 3 0 CAMSAP CH domain zf-TRAF PF02176.13 ETO01050.1 - 3.1e-06 27.4 0.7 3.1e-06 27.4 0.5 3.3 3 1 1 4 4 4 1 TRAF-type zinc finger RNB PF00773.14 ETO01050.1 - 0.091 12.0 0.2 0.1 11.8 0.1 1.1 1 0 0 1 1 1 0 RNB domain Kelch_1 PF01344.20 ETO01052.1 - 1.4e-05 24.5 4.0 4.8e-05 22.8 0.1 2.9 3 1 1 4 4 4 1 Kelch motif Kelch_2 PF07646.10 ETO01052.1 - 0.0024 17.5 0.6 0.028 14.1 0.1 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETO01052.1 - 0.0034 17.4 2.5 0.9 9.8 0.3 3.0 1 1 1 2 2 2 2 Kelch motif Kelch_4 PF13418.1 ETO01052.1 - 0.0064 16.2 1.5 2.2 8.1 0.1 2.9 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO01052.1 - 0.15 12.2 0.2 0.9 9.7 0.0 2.3 3 0 0 3 3 3 0 Galactose oxidase, central domain DUF1725 PF08333.6 ETO01052.1 - 0.84 9.0 0.0 0.84 9.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1725) Kelch_2 PF07646.10 ETO01055.1 - 1.2e-05 24.8 0.1 0.0018 18.0 0.1 2.2 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 ETO01055.1 - 8.1e-05 22.3 0.1 0.0029 17.3 0.0 2.2 1 1 1 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO01055.1 - 0.00013 21.4 1.4 0.00028 20.3 1.0 1.5 1 0 0 1 1 1 1 Kelch motif Kelch_6 PF13964.1 ETO01055.1 - 0.00021 21.3 0.3 0.0087 16.1 0.1 2.3 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO01055.1 - 0.014 15.5 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO01055.1 - 0.031 14.2 0.2 5.8 6.9 0.5 2.4 2 0 0 2 2 2 0 Kelch motif DUF912 PF06024.7 ETO01056.1 - 0.39 10.8 3.3 0.83 9.7 2.3 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Corona_nucleoca PF00937.13 ETO01057.1 - 1.2 7.9 33.0 1.4 7.7 7.5 2.3 1 1 1 2 2 2 0 Coronavirus nucleocapsid protein Macoilin PF09726.4 ETO01057.1 - 9.4 4.3 12.8 12 4.0 8.9 1.2 1 0 0 1 1 1 0 Transmembrane protein Cobl PF09469.5 ETO01058.1 - 0.027 14.4 0.4 0.57 10.1 0.2 2.2 1 1 0 1 1 1 0 Cordon-bleu ubiquitin-like domain DUF4173 PF13777.1 ETO01058.1 - 0.074 12.3 4.9 1.8 7.7 0.1 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4173) His_biosynth PF00977.16 ETO01058.1 - 0.12 11.6 1.0 0.4 9.8 0.6 1.7 1 1 1 2 2 2 0 Histidine biosynthesis protein PsbY PF06298.6 ETO01058.1 - 0.25 10.8 6.3 6.9 6.2 1.5 3.5 2 1 1 3 3 3 0 Photosystem II protein Y (PsbY) DUF3072 PF11272.3 ETO01058.1 - 0.28 10.8 3.1 14 5.4 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3072) PspB PF06667.7 ETO01060.1 - 0.081 12.8 0.4 2.9 7.8 0.0 2.6 2 0 0 2 2 2 0 Phage shock protein B DASH_Dam1 PF08653.5 ETO01060.1 - 0.19 11.5 2.5 0.26 11.0 0.1 2.3 3 0 0 3 3 3 0 DASH complex subunit Dam1 DivIC PF04977.10 ETO01060.1 - 1.8 8.0 7.5 1.4 8.4 1.2 3.0 2 0 0 2 2 2 0 Septum formation initiator BLOC1_2 PF10046.4 ETO01060.1 - 6.1 7.0 11.5 1.1 9.4 1.0 3.2 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_DNA_bd PF12329.3 ETO01060.1 - 9.1 6.1 13.6 0.52 10.1 0.6 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding MIP-T3 PF10243.4 ETO01062.1 - 9.9e-05 20.9 49.9 9.9e-05 20.9 34.6 2.5 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 Memo PF01875.12 ETO01064.1 - 1.5e-65 220.8 0.3 1.7e-65 220.6 0.2 1.0 1 0 0 1 1 1 1 Memo-like protein HmuY PF14064.1 ETO01065.1 - 0.061 13.3 0.3 0.064 13.2 0.2 1.1 1 0 0 1 1 1 0 HmuY protein Asp_Arg_Hydrox PF05118.10 ETO01066.1 - 9.6e-09 35.2 0.8 1.7e-07 31.1 0.1 2.3 2 1 0 2 2 2 1 Aspartyl/Asparaginyl beta-hydroxylase PBP_sp32 PF07222.7 ETO01066.1 - 0.052 12.7 1.6 0.06 12.5 1.1 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 FAM176 PF14851.1 ETO01066.1 - 0.062 12.9 0.6 0.079 12.6 0.4 1.2 1 0 0 1 1 1 0 FAM176 family BSP_II PF05432.6 ETO01066.1 - 0.08 12.2 4.7 0.1 11.8 3.2 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TatD_DNase PF01026.16 ETO01067.1 - 9.9e-11 41.3 0.0 1.1e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase DUF2201_N PF13203.1 ETO01067.1 - 0.0048 16.1 7.8 0.0048 16.1 5.4 1.4 2 0 0 2 2 2 1 Putative metallopeptidase domain Zip PF02535.17 ETO01067.1 - 0.011 14.7 1.2 0.015 14.3 0.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.7 ETO01067.1 - 0.27 9.1 37.0 0.014 13.4 20.3 1.9 2 0 0 2 2 2 0 Nop14-like family Menin PF05053.8 ETO01067.1 - 1.1 7.3 9.9 1.3 7.1 6.9 1.3 1 0 0 1 1 1 0 Menin Raftlin PF15250.1 ETO01067.1 - 1.3 7.4 16.4 0.059 11.8 7.8 1.3 2 0 0 2 2 2 0 Raftlin Herpes_LMP1 PF05297.6 ETO01067.1 - 4.5 6.1 19.0 5.2 5.8 13.1 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Mem_trans PF03547.13 ETO01067.1 - 4.5 5.4 6.0 6.3 4.9 4.2 1.2 1 0 0 1 1 1 0 Membrane transport protein Hid1 PF12722.2 ETO01067.1 - 4.8 4.7 20.3 6.3 4.3 14.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF848 PF05852.6 ETO01069.1 - 0.014 15.2 15.4 0.35 10.6 3.6 2.6 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF3683 PF12447.3 ETO01069.1 - 0.47 10.2 4.0 12 5.7 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3683) Vps51 PF08700.6 ETO01069.1 - 0.61 9.9 6.4 4.6 7.1 0.1 3.4 3 1 0 3 3 3 0 Vps51/Vps67 COG5 PF10392.4 ETO01069.1 - 0.61 10.0 6.2 0.31 11.0 0.5 2.8 2 1 0 2 2 2 0 Golgi transport complex subunit 5 Rotamase PF00639.16 ETO01069.1 - 0.65 10.7 3.7 5.9 7.7 0.1 2.8 2 1 0 2 2 2 0 PPIC-type PPIASE domain Img2 PF05046.9 ETO01069.1 - 0.83 9.9 6.2 0.35 11.1 0.3 2.9 2 1 1 3 3 3 0 Mitochondrial large subunit ribosomal protein (Img2) Syntaxin-6_N PF09177.6 ETO01069.1 - 2.6 8.5 10.8 1.9 8.9 0.8 3.9 3 2 0 3 3 3 0 Syntaxin 6, N-terminal Mer2 PF09074.5 ETO01069.1 - 3.6 7.4 24.8 13 5.6 13.0 2.9 1 1 2 3 3 3 0 Mer2 RTTN_N PF14726.1 ETO01070.1 - 0.0089 16.5 0.2 0.023 15.2 0.1 1.7 1 1 0 1 1 1 1 Rotatin, an armadillo repeat protein, centriole functioning GCHY-1 PF02649.9 ETO01070.1 - 0.038 13.2 0.9 0.064 12.4 0.6 1.3 1 0 0 1 1 1 0 Type I GTP cyclohydrolase folE2 MH1 PF03165.11 ETO01070.1 - 0.36 10.8 3.1 1.3 9.0 0.3 2.1 2 0 0 2 2 2 0 MH1 domain RasGAP PF00616.14 ETO01070.1 - 0.95 9.0 5.5 2 8.0 3.8 1.6 1 1 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase MraZ PF02381.13 ETO01071.1 - 0.079 12.7 0.2 0.56 9.9 0.1 2.1 2 0 0 2 2 2 0 MraZ protein TPR_12 PF13424.1 ETO01072.1 - 5.4e-160 519.7 17.2 2.6e-25 88.1 0.1 5.7 1 1 7 8 8 8 8 Tetratricopeptide repeat TPR_11 PF13414.1 ETO01072.1 - 1.7e-66 219.7 32.4 4.3e-16 58.3 0.8 4.8 2 2 4 6 6 6 6 TPR repeat TPR_7 PF13176.1 ETO01072.1 - 4.1e-62 201.1 7.2 1e-08 34.3 0.0 8.2 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_10 PF13374.1 ETO01072.1 - 1.3e-58 193.3 0.0 2.4e-07 30.4 0.0 9.0 9 1 0 9 9 9 7 Tetratricopeptide repeat TPR_1 PF00515.23 ETO01072.1 - 4.2e-56 184.3 42.2 2.1e-09 36.5 0.3 8.6 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.12 ETO01072.1 - 1.2e-42 140.4 23.1 1e-06 28.2 0.1 7.6 8 0 0 8 8 7 7 Tetratricopeptide repeat TPR_8 PF13181.1 ETO01072.1 - 4.4e-38 126.2 53.8 4.4e-08 32.3 1.7 7.9 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_17 PF13431.1 ETO01072.1 - 9.2e-25 84.7 14.9 0.0021 18.0 0.0 9.6 7 5 0 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 ETO01072.1 - 8.4e-20 70.9 0.0 0.00037 21.0 0.0 5.3 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.1 ETO01072.1 - 8e-18 63.3 0.0 0.39 11.4 0.0 7.3 5 2 2 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 ETO01072.1 - 7.7e-13 48.3 9.9 1.6e-05 24.9 1.0 4.1 2 1 4 6 6 6 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO01072.1 - 8e-13 48.5 0.4 0.021 15.1 0.1 5.2 1 1 5 6 6 6 6 Tetratricopeptide repeat TPR_6 PF13174.1 ETO01072.1 - 1.2e-12 47.3 4.5 0.081 13.4 0.0 7.4 7 0 0 7 7 7 1 Tetratricopeptide repeat SNAP PF14938.1 ETO01072.1 - 8.6e-12 44.7 7.0 0.00048 19.3 1.0 4.4 1 1 2 4 4 4 3 Soluble NSF attachment protein, SNAP MIT PF04212.13 ETO01072.1 - 5.6e-11 42.1 29.1 0.0082 15.9 0.4 7.0 6 1 1 7 7 7 5 MIT (microtubule interacting and transport) domain PPR PF01535.15 ETO01072.1 - 1.6e-08 33.9 17.7 0.89 9.6 0.1 7.0 7 0 0 7 7 7 3 PPR repeat Musclin PF11037.3 ETO01072.1 - 0.00048 19.7 0.0 3.2 7.3 0.0 4.4 4 1 1 5 5 4 1 Insulin-resistance promoting peptide in skeletal muscle Ten1_2 PF15490.1 ETO01072.1 - 0.00095 18.7 0.0 9.5 5.8 0.0 4.7 3 3 2 5 5 5 0 Telomere-capping, CST complex subunit NdhO PF11910.3 ETO01072.1 - 0.0042 16.6 7.3 2.1 8.0 0.0 4.4 3 1 2 5 5 4 2 Cyanobacterial and plant NDH-1 subunit O DUF627 PF04781.7 ETO01072.1 - 0.0047 16.5 12.8 4.3 7.0 0.7 6.2 4 2 2 6 6 6 1 Protein of unknown function (DUF627) DUF3568 PF12092.3 ETO01072.1 - 0.0055 16.4 0.2 59 3.3 0.0 5.0 2 2 3 6 6 6 0 Protein of unknown function (DUF3568) TPR_3 PF07720.7 ETO01072.1 - 0.0092 15.7 30.9 0.58 10.0 0.3 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat HemS PF05171.7 ETO01072.1 - 0.0094 15.7 0.0 1.6 8.5 0.0 3.0 3 0 0 3 3 3 1 Haemin-degrading HemS.ChuX domain SHNi-TPR PF10516.4 ETO01072.1 - 0.0097 15.1 9.3 4.3 6.6 0.1 5.9 7 0 0 7 7 7 1 SHNi-TPR DUF2225 PF09986.4 ETO01072.1 - 0.019 14.4 11.5 6.1 6.2 3.0 3.8 2 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_9 PF13371.1 ETO01072.1 - 0.024 14.4 0.0 10 6.0 0.0 3.4 2 2 0 3 3 3 0 Tetratricopeptide repeat TPR_5 PF12688.2 ETO01072.1 - 0.027 14.4 0.2 5.5 7.0 0.0 3.6 2 2 2 4 4 4 0 Tetratrico peptide repeat RPN7 PF10602.4 ETO01072.1 - 0.11 11.8 12.8 4.5 6.6 1.4 5.0 2 2 3 5 5 5 0 26S proteasome subunit RPN7 UPF0223 PF05256.7 ETO01072.1 - 0.11 12.6 3.6 1.2 9.3 0.2 3.2 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0223) Clathrin PF00637.15 ETO01072.1 - 0.29 10.7 16.6 4.2 6.9 2.2 5.6 2 2 3 5 5 5 0 Region in Clathrin and VPS Fis1_TPR_C PF14853.1 ETO01072.1 - 0.97 9.3 25.7 0.95 9.3 0.3 7.0 8 0 0 8 8 8 0 Fis1 C-terminal tetratricopeptide repeat Sel1 PF08238.7 ETO01072.1 - 2.7 8.7 17.8 4.1 8.1 0.1 6.5 7 0 0 7 7 7 0 Sel1 repeat DUF1186 PF06685.6 ETO01072.1 - 5.8 5.9 7.0 42 3.1 0.2 3.5 3 1 0 4 4 3 0 Protein of unknown function (DUF1186) Mob_Pre PF01076.14 ETO01072.1 - 8.7 5.9 7.5 15 5.1 0.1 3.6 2 1 3 5 5 5 0 Plasmid recombination enzyme ABC_tran PF00005.22 ETO01073.1 - 5.9e-14 52.5 0.0 1.1e-13 51.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_ATPase PF09818.4 ETO01073.1 - 2.8e-06 26.2 0.0 3.3e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class SMC_N PF02463.14 ETO01073.1 - 4.5e-05 22.7 0.0 5e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 ETO01073.1 - 0.00058 19.7 0.9 0.0073 16.2 0.6 2.1 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 ETO01073.1 - 0.011 15.7 0.0 0.011 15.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 ETO01073.1 - 0.016 15.3 0.0 0.022 14.9 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) WD40 PF00400.27 ETO01074.1 - 3.1e-58 191.7 20.9 2.1e-12 46.4 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO01074.1 - 1.7e-09 36.3 5.0 0.35 8.9 0.0 5.9 3 2 3 6 6 6 6 Nucleoporin Nup120/160 SAM_1 PF00536.25 ETO01075.1 - 7.6e-19 67.6 0.2 5.7e-09 36.0 0.0 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO01075.1 - 1.6e-17 63.0 0.3 4.2e-08 32.9 0.0 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 ETO01075.1 - 0.0006 19.5 0.1 0.0045 16.7 0.0 2.3 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain Nucleoplasmin PF03066.10 ETO01075.1 - 0.045 13.2 11.9 0.074 12.5 2.6 2.5 2 0 0 2 2 2 0 Nucleoplasmin Nro1 PF12753.2 ETO01075.1 - 0.061 12.2 16.1 0.19 10.6 5.6 2.5 2 1 0 2 2 2 0 Nuclear pore complex subunit Nro1 BSP_II PF05432.6 ETO01075.1 - 0.85 8.8 24.1 0.92 8.7 0.3 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) FAM176 PF14851.1 ETO01075.1 - 1.7 8.3 13.3 0.15 11.7 1.8 2.7 3 0 0 3 3 3 0 FAM176 family Vpu PF00558.14 ETO01075.1 - 3 7.4 7.8 0.55 9.8 2.0 2.3 2 0 0 2 2 2 0 Vpu protein Gemini_mov PF01708.11 ETO01076.1 - 0.076 12.5 0.1 0.076 12.5 0.1 1.8 2 0 0 2 2 2 0 Geminivirus putative movement protein RNA_lig_T4_1 PF09511.5 ETO01077.1 - 0.0021 17.5 0.0 0.0025 17.3 0.0 1.0 1 0 0 1 1 1 1 RNA ligase WD40 PF00400.27 ETO01081.1 - 7.7e-65 212.6 12.9 1.5e-13 50.0 0.3 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO01081.1 - 1.6e-10 39.8 3.7 0.021 12.9 0.0 4.0 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO01081.1 - 9.4e-06 24.6 2.5 0.075 11.7 0.1 3.8 1 1 1 2 2 2 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO01081.1 - 0.00014 20.2 0.4 0.023 13.0 0.0 2.2 1 1 0 2 2 2 2 Cytochrome D1 heme domain Gmad1 PF10647.4 ETO01081.1 - 0.00045 19.6 0.2 3.8 6.8 0.0 3.0 2 1 1 3 3 3 1 Lipoprotein LpqB beta-propeller domain PQQ_2 PF13360.1 ETO01081.1 - 0.0058 16.1 0.4 0.97 8.8 0.0 3.1 1 1 0 2 2 2 1 PQQ-like domain PD40 PF07676.7 ETO01081.1 - 0.012 15.2 3.4 64 3.3 0.0 4.8 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO01081.1 - 0.013 15.7 0.5 12 6.2 0.0 3.6 2 1 2 4 4 4 0 Resistin DUF3601 PF12208.3 ETO01081.1 - 0.089 12.7 0.1 1.2 9.1 0.0 2.8 3 2 1 4 4 4 0 Domain of unknown function (DUF3601) Proteasome_A_N PF10584.4 ETO01081.1 - 1.4 8.2 5.3 34 3.8 0.0 4.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature HMG-CoA_red PF00368.13 ETO01082.1 - 1.4e-65 221.3 0.1 1.9e-65 220.9 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase LURAP PF14854.1 ETO01083.1 - 0.15 11.8 0.2 0.22 11.2 0.2 1.2 1 0 0 1 1 1 0 Leucine rich adaptor protein DUF4604 PF15377.1 ETO01083.1 - 0.48 10.6 12.7 0.62 10.2 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Bap31 PF05529.7 ETO01083.1 - 2.4 7.5 6.6 4.2 6.7 4.6 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like YMF19 PF02326.10 ETO01083.1 - 3.2 8.3 8.9 14 6.3 3.5 2.2 2 0 0 2 2 2 0 Plant ATP synthase F0 WD40 PF00400.27 ETO01084.1 - 7.1e-34 114.4 12.5 1.4e-12 46.9 0.0 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO01084.1 - 8.5e-07 27.4 0.8 0.0049 15.0 0.2 2.3 1 1 0 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO01084.1 - 0.01 15.5 0.4 0.033 13.9 0.2 1.7 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF3601 PF12208.3 ETO01084.1 - 0.078 12.9 0.0 0.19 11.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3601) DUF2559 PF10832.3 ETO01084.1 - 0.31 10.8 1.4 5.2 6.9 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2559) HEAT PF02985.17 ETO01085.1 - 5.6e-24 82.0 17.0 0.0013 18.6 0.1 11.9 12 1 1 13 13 13 6 HEAT repeat HEAT_2 PF13646.1 ETO01085.1 - 1.9e-21 76.1 0.0 0.0045 17.2 0.0 7.2 3 1 5 8 8 8 6 HEAT repeats Vac14_Fab1_bd PF12755.2 ETO01085.1 - 3.8e-08 33.6 6.4 1.1 9.6 0.0 6.6 4 2 2 6 6 6 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 ETO01085.1 - 3e-06 27.5 2.9 0.97 10.0 0.0 7.6 7 1 2 9 9 9 1 HEAT-like repeat Cnd3 PF12719.2 ETO01085.1 - 0.00062 18.8 2.2 0.029 13.3 0.3 3.1 1 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Cohesin_HEAT PF12765.2 ETO01085.1 - 0.003 17.4 0.3 5.9 6.9 0.0 3.3 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion PB1 PF00564.19 ETO01086.1 - 0.026 14.1 0.3 0.036 13.7 0.2 1.2 1 0 0 1 1 1 0 PB1 domain DUF4496 PF14908.1 ETO01087.1 - 0.095 12.5 0.3 0.17 11.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4496) Spc97_Spc98 PF04130.8 ETO01088.1 - 5.3e-14 51.4 0.1 8.4e-14 50.7 0.1 1.2 1 1 0 1 1 1 1 Spc97 / Spc98 family SPO22 PF08631.5 ETO01088.1 - 0.047 12.7 0.1 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like Tht1 PF04163.7 ETO01088.1 - 0.089 11.1 0.1 0.11 10.8 0.1 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein Aldedh PF00171.17 ETO01089.1 - 2.6e-15 55.7 0.0 2.8e-15 55.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cellulase PF00150.13 ETO01089.1 - 0.0048 16.1 0.0 0.0048 16.1 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Zeta_toxin PF06414.7 ETO01089.1 - 0.058 12.4 0.0 0.068 12.2 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin 14-3-3 PF00244.15 ETO01090.1 - 0.0034 16.4 0.4 0.0049 15.9 0.2 1.4 1 1 0 1 1 1 1 14-3-3 protein DUF1040 PF06288.8 ETO01090.1 - 0.3 11.3 1.4 4.9 7.4 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1040) HSP70 PF00012.15 ETO01091.1 - 1.5e-112 376.5 0.4 9.6e-112 373.8 0.3 1.8 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 ETO01091.1 - 2.8e-16 59.0 0.0 3.7e-16 58.6 0.0 1.0 1 0 0 1 1 1 1 MreB/Mbl protein Hydantoinase_A PF01968.13 ETO01091.1 - 0.00031 19.9 0.1 0.00052 19.2 0.1 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase PilM_2 PF11104.3 ETO01091.1 - 0.073 11.9 0.0 0.98 8.2 0.0 2.0 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; DUF2618 PF10940.3 ETO01091.1 - 0.19 11.5 0.4 0.4 10.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2618) Enterotoxin_ST PF02048.11 ETO01091.1 - 0.26 11.5 3.4 0.4 10.9 0.2 2.3 2 0 0 2 2 2 0 Heat-stable enterotoxin ST EST1_DNA_bind PF10373.4 ETO01093.1 - 1.8e-08 33.9 2.2 1.1e-07 31.4 0.1 2.4 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain TPR_11 PF13414.1 ETO01093.1 - 2.2e-07 30.3 0.0 1.4e-06 27.8 0.0 2.4 2 0 0 2 2 2 1 TPR repeat TPR_17 PF13431.1 ETO01093.1 - 0.0013 18.7 0.4 0.007 16.4 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat EST1 PF10374.4 ETO01093.1 - 0.0032 17.4 2.5 0.0032 17.4 1.7 2.0 2 1 0 2 2 2 1 Telomerase activating protein Est1 TPR_2 PF07719.12 ETO01093.1 - 0.031 14.1 0.0 1.4 9.0 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETO01093.1 - 0.081 12.8 1.0 0.56 10.1 0.0 2.6 1 1 2 3 3 3 0 Tetratricopeptide repeat KilA-N PF04383.8 ETO01093.1 - 0.17 11.4 0.1 0.17 11.4 0.1 2.0 2 1 1 3 3 3 0 KilA-N domain DUF3106 PF11304.3 ETO01093.1 - 0.84 10.0 14.7 0.035 14.5 2.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3106) WD40 PF00400.27 ETO01094.1 - 8.2e-11 41.3 4.7 1.9e-09 37.0 0.4 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat AAA_18 PF13238.1 ETO01096.1 - 0.00066 19.9 2.0 0.0054 17.0 0.0 2.9 2 1 0 3 3 3 1 AAA domain AAA_17 PF13207.1 ETO01096.1 - 0.0007 20.4 0.1 0.012 16.3 0.0 2.7 2 1 1 3 3 3 1 AAA domain NACHT PF05729.7 ETO01096.1 - 0.0012 18.5 0.0 0.0026 17.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain UPF0079 PF02367.12 ETO01096.1 - 0.0025 17.4 0.0 0.0077 15.8 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 ETO01096.1 - 0.0051 16.9 0.0 0.014 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 ETO01096.1 - 0.033 14.3 0.3 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 RNA helicase KAP_NTPase PF07693.9 ETO01096.1 - 0.038 12.9 0.0 0.077 11.9 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain ABC_tran PF00005.22 ETO01096.1 - 0.048 13.9 0.0 0.15 12.3 0.0 1.8 2 1 0 2 2 2 0 ABC transporter Torsin PF06309.6 ETO01096.1 - 0.061 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_5 PF07728.9 ETO01096.1 - 0.075 12.7 0.0 0.83 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PRK PF00485.13 ETO01096.1 - 0.076 12.5 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.1 ETO01096.1 - 0.096 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain KaiC PF06745.8 ETO01096.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.1 ETO01096.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Med28 PF11594.3 ETO01096.1 - 1.9 8.7 6.0 5.4 7.2 0.1 2.9 2 1 1 3 3 3 0 Mediator complex subunit 28 EIIBC-GUT_N PF03612.9 ETO01097.1 - 6.3 6.3 6.1 2.5 7.6 0.3 2.6 2 1 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus FAM70 PF14967.1 ETO01097.1 - 8.1 5.5 8.4 12 4.9 5.8 1.3 1 0 0 1 1 1 0 FAM70 protein FANCI_S2 PF14676.1 ETO01098.1 - 0.18 11.6 1.3 1.5 8.6 0.0 2.1 2 0 0 2 2 2 0 FANCI solenoid 2 IBB PF01749.15 ETO01100.1 - 1.2 9.2 8.2 0.21 11.7 2.6 1.9 2 0 0 2 2 2 0 Importin beta binding domain RCC1_2 PF13540.1 ETO01101.1 - 1.8e-09 36.9 9.0 6e-05 22.5 0.1 3.4 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 ETO01101.1 - 3.9e-07 30.1 2.1 0.6 10.3 0.0 4.2 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat Mucin PF01456.12 ETO01101.1 - 0.017 14.8 39.5 0.031 14.0 27.4 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Adeno_PIX PF03955.9 ETO01101.1 - 0.029 14.9 6.4 0.056 13.9 4.4 1.4 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) Orbi_VP4 PF05059.7 ETO01101.1 - 0.15 9.8 1.5 0.2 9.3 1.1 1.1 1 0 0 1 1 1 0 Orbivirus VP4 core protein Sporozoite_P67 PF05642.6 ETO01101.1 - 0.25 9.1 9.3 0.4 8.5 6.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MGC-24 PF05283.6 ETO01101.1 - 0.54 10.0 21.3 1.1 9.0 14.8 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Rifin_STEVOR PF02009.11 ETO01101.1 - 1.4 8.5 6.0 2 7.9 4.1 1.2 1 0 0 1 1 1 0 Rifin/stevor family MSP1_C PF07462.6 ETO01101.1 - 5.4 5.2 11.3 7.6 4.7 7.8 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF1049 PF06305.6 ETO01102.1 - 2.6 7.5 6.2 0.31 10.5 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1049) Peptidase_C65 PF10275.4 ETO01103.1 - 0.00054 19.3 0.2 0.00057 19.3 0.1 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 ETO01103.1 - 0.002 18.7 0.0 0.0021 18.6 0.0 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease Ank_2 PF12796.2 ETO01104.1 - 4e-12 46.2 0.1 1.3e-10 41.4 0.1 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO01104.1 - 1.1e-11 43.8 0.0 3.6e-07 29.6 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 ETO01104.1 - 1.2e-10 40.5 0.4 3.9e-05 23.4 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 ETO01104.1 - 2.9e-09 37.1 0.7 2e-08 34.5 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO01104.1 - 2.9e-07 30.5 1.8 3.5e-06 27.0 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Vif PF00559.12 ETO01104.1 - 0.084 12.7 0.7 3.7 7.3 0.2 2.1 2 0 0 2 2 2 0 Retroviral Vif (Viral infectivity) protein DNA_pol_E_B PF04042.11 ETO01104.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B zf-H2C2_2 PF13465.1 ETO01106.1 - 0.0023 18.1 6.8 0.14 12.4 1.8 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 ETO01106.1 - 0.0061 16.8 12.5 0.095 13.0 1.3 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETO01106.1 - 0.22 11.9 12.7 1 9.8 1.4 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 ETO01106.1 - 1.7 8.6 5.6 12 5.9 0.1 2.7 2 0 0 2 2 2 0 Zinc ribbon domain U-box PF04564.10 ETO01108.1 - 0.14 12.1 0.4 0.21 11.5 0.3 1.3 1 0 0 1 1 1 0 U-box domain HEAT_EZ PF13513.1 ETO01109.1 - 0.015 15.7 0.0 0.044 14.2 0.0 1.7 2 0 0 2 2 2 0 HEAT-like repeat DUF999 PF06198.6 ETO01109.1 - 0.024 14.4 0.8 0.039 13.7 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF999) HEAT_2 PF13646.1 ETO01109.1 - 0.068 13.4 0.0 0.11 12.7 0.0 1.7 1 1 0 1 1 1 0 HEAT repeats WD40 PF00400.27 ETO01110.1 - 3e-15 55.4 4.2 2.9e-09 36.4 0.0 3.3 3 1 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO01110.1 - 0.0088 14.2 0.1 1.2 7.1 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 zf-RVT PF13966.1 ETO01112.1 - 0.00013 22.1 0.2 0.00018 21.7 0.1 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Daxx PF03344.10 ETO01113.1 - 0.37 9.2 59.3 0.48 8.8 41.1 1.1 1 0 0 1 1 1 0 Daxx Family Tubulin PF00091.20 ETO01115.1 - 3.7e-30 105.3 0.5 2.9e-24 86.1 0.0 2.0 1 1 1 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.1 ETO01115.1 - 0.0028 16.6 0.2 0.004 16.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin like Ank_2 PF12796.2 ETO01116.1 - 1.4e-25 89.4 2.0 2e-13 50.4 0.2 2.8 2 1 3 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO01116.1 - 6.5e-14 51.9 0.2 1.1e-07 32.1 0.1 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 ETO01116.1 - 1.1e-12 47.0 3.6 5e-06 26.0 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 ETO01116.1 - 3e-11 43.1 6.1 9.6e-08 32.0 0.3 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO01116.1 - 7.1e-11 41.2 2.3 0.00078 19.4 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat RXT2_N PF08595.6 ETO01116.1 - 4 7.2 11.1 0.38 10.5 1.5 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF3439 PF11921.3 ETO01117.1 - 3.7 7.3 19.2 0.49 10.1 10.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 ETO01117.1 - 4.8 4.8 5.8 5.1 4.7 4.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein WD40 PF00400.27 ETO01118.1 - 1.7e-34 116.4 3.0 1.7e-10 40.3 0.0 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO01118.1 - 0.0037 15.4 1.1 1 7.4 0.3 2.9 2 1 0 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO01118.1 - 0.021 14.5 0.0 0.035 13.8 0.0 1.5 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 ETO01118.1 - 0.048 12.4 2.6 3 6.5 0.1 2.6 1 1 0 2 2 2 0 Nup133 N terminal like Coatomer_WDAD PF04053.9 ETO01118.1 - 0.063 12.0 0.0 0.071 11.8 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region Pkinase PF00069.20 ETO01119.1 - 0.00045 19.4 0.1 0.00065 18.9 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO01119.1 - 0.0085 15.1 0.1 0.011 14.7 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2457 PF10446.4 ETO01120.1 - 0.00045 19.0 17.7 0.00049 18.9 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Nop14 PF04147.7 ETO01120.1 - 0.028 12.3 10.3 0.033 12.1 7.1 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 ETO01120.1 - 0.13 10.7 13.1 0.15 10.5 9.1 1.2 1 0 0 1 1 1 0 Daxx Family eIF-3c_N PF05470.7 ETO01120.1 - 0.53 8.3 4.9 0.44 8.5 3.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus BUD22 PF09073.5 ETO01120.1 - 2.1 7.3 9.9 2.2 7.2 6.9 1.2 1 0 0 1 1 1 0 BUD22 BSP_II PF05432.6 ETO01120.1 - 2.7 7.2 18.6 3.7 6.7 12.9 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF3252 PF11623.3 ETO01121.1 - 0.074 12.4 0.3 0.18 11.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3252) YL1 PF05764.8 ETO01123.1 - 0.19 11.3 16.1 0.23 11.0 11.2 1.1 1 0 0 1 1 1 0 YL1 nuclear protein SR-25 PF10500.4 ETO01123.1 - 1.1 8.7 15.9 1.5 8.1 11.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CENP-H PF05837.7 ETO01123.1 - 2 8.6 8.3 1.3 9.2 2.1 2.0 2 0 0 2 2 2 0 Centromere protein H (CENP-H) NACHT PF05729.7 ETO01125.1 - 4.8e-09 36.1 0.0 6.7e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 NACHT domain DUF762 PF05555.6 ETO01125.1 - 0.039 13.1 0.1 0.048 12.9 0.1 1.1 1 0 0 1 1 1 0 Coxiella burnetii protein of unknown function (DUF762) DUF1249 PF06853.7 ETO01125.1 - 0.32 10.6 1.8 1 8.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1249) GAS PF13851.1 ETO01126.1 - 1.6e-05 24.1 10.0 1.6e-05 24.1 6.9 2.5 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.2 ETO01126.1 - 2.6e-05 24.0 30.5 0.0003 20.6 7.7 2.4 1 1 1 2 2 2 2 Tropomyosin like Seryl_tRNA_N PF02403.17 ETO01126.1 - 0.0007 19.5 7.7 0.0007 19.5 5.3 2.5 1 1 1 2 2 2 1 Seryl-tRNA synthetase N-terminal domain RmuC PF02646.11 ETO01126.1 - 0.0007 18.5 2.5 0.0007 18.5 1.7 2.9 1 1 2 3 3 3 1 RmuC family bZIP_1 PF00170.16 ETO01126.1 - 0.00071 19.4 7.5 0.011 15.6 0.5 4.0 2 2 1 3 3 2 2 bZIP transcription factor DASH_Hsk3 PF08227.6 ETO01126.1 - 0.0022 18.1 0.7 0.82 9.9 0.0 2.7 2 0 0 2 2 2 1 DASH complex subunit Hsk3 like Phage_GP20 PF06810.6 ETO01126.1 - 0.0035 16.7 7.9 0.0035 16.7 5.5 2.7 1 1 1 2 2 1 1 Phage minor structural protein GP20 Reo_sigmaC PF04582.7 ETO01126.1 - 0.0049 16.0 2.6 0.0067 15.6 1.8 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 ETO01126.1 - 0.0061 14.3 30.2 0.042 11.5 20.9 1.9 1 1 0 1 1 1 1 Myosin tail CENP-F_leu_zip PF10473.4 ETO01126.1 - 0.013 15.3 7.0 0.013 15.3 4.9 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.7 ETO01126.1 - 0.022 15.0 9.0 4.4 7.6 0.1 3.3 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF972 PF06156.8 ETO01126.1 - 0.03 14.6 3.3 0.03 14.6 2.3 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF972) IncA PF04156.9 ETO01126.1 - 0.033 13.7 29.0 0.67 9.5 20.1 2.3 1 1 0 1 1 1 0 IncA protein Baculo_PEP_C PF04513.7 ETO01126.1 - 0.042 13.6 2.0 0.18 11.6 1.4 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.6 ETO01126.1 - 0.052 13.4 5.3 0.063 13.1 0.5 2.7 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Microtub_assoc PF07989.6 ETO01126.1 - 0.06 13.1 0.4 0.06 13.1 0.3 3.2 2 1 1 3 3 2 0 Microtubule associated TraF_2 PF13729.1 ETO01126.1 - 0.098 11.4 0.5 0.15 10.8 0.3 1.4 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein Prefoldin_2 PF01920.15 ETO01126.1 - 0.099 12.4 0.5 0.099 12.4 0.3 4.0 1 1 2 4 4 4 0 Prefoldin subunit HSBP1 PF06825.7 ETO01126.1 - 0.12 11.9 10.2 0.38 10.3 0.4 3.6 2 2 0 2 2 2 0 Heat shock factor binding protein 1 FlaC_arch PF05377.6 ETO01126.1 - 0.12 12.2 13.5 7.6 6.5 1.7 3.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) ATG16 PF08614.6 ETO01126.1 - 0.13 12.0 26.2 0.12 12.1 4.1 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Tropomyosin PF00261.15 ETO01126.1 - 0.15 11.1 28.5 0.64 9.0 19.8 1.9 1 1 0 1 1 1 0 Tropomyosin HALZ PF02183.13 ETO01126.1 - 0.15 11.7 8.8 0.95 9.2 0.1 3.5 3 1 1 4 4 3 0 Homeobox associated leucine zipper DUF4254 PF14063.1 ETO01126.1 - 0.16 11.5 10.5 0.29 10.7 7.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4254) PEARLI-4 PF05278.7 ETO01126.1 - 0.27 10.5 23.0 0.14 11.5 2.3 2.1 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF3450 PF11932.3 ETO01126.1 - 0.27 10.4 18.7 0.068 12.4 8.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) V_ATPase_I PF01496.14 ETO01126.1 - 0.34 8.7 15.9 0.61 7.8 11.0 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_2 PF07716.10 ETO01126.1 - 0.35 10.7 0.2 0.35 10.7 0.1 5.0 4 2 2 6 6 4 0 Basic region leucine zipper Phlebovirus_NSM PF07246.6 ETO01126.1 - 0.39 9.8 16.7 0.11 11.6 9.1 1.7 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M Filament PF00038.16 ETO01126.1 - 0.63 9.4 24.1 0.99 8.8 2.5 2.2 1 1 1 2 2 2 0 Intermediate filament protein Syntaxin_2 PF14523.1 ETO01126.1 - 0.7 9.9 19.5 3.4 7.7 0.7 2.5 1 1 1 2 2 2 0 Syntaxin-like protein DUF724 PF05266.9 ETO01126.1 - 0.87 9.1 27.8 0.15 11.6 13.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Laminin_II PF06009.7 ETO01126.1 - 0.9 9.2 16.3 1.1 8.9 6.1 2.7 1 1 1 2 2 2 0 Laminin Domain II TPR_MLP1_2 PF07926.7 ETO01126.1 - 1.4 8.6 25.9 5.2 6.8 17.6 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein ADIP PF11559.3 ETO01126.1 - 1.5 8.7 29.1 0.14 12.0 4.8 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding MbeD_MobD PF04899.7 ETO01126.1 - 1.5 8.7 12.4 1.7 8.6 1.5 3.4 1 1 2 3 3 3 0 MbeD/MobD like DUF3287 PF11690.3 ETO01126.1 - 1.7 8.7 14.6 0.39 10.8 1.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3287) Lectin_N PF03954.9 ETO01126.1 - 1.8 7.9 11.5 1.1 8.6 1.8 2.7 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Nup54 PF13874.1 ETO01126.1 - 1.9 8.1 20.7 4.3 6.9 0.5 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 CALCOCO1 PF07888.6 ETO01126.1 - 2.1 6.5 22.8 3.1 5.9 15.8 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2205 PF10224.4 ETO01126.1 - 2.2 7.9 20.1 0.57 9.7 4.1 3.1 1 1 2 3 3 3 0 Predicted coiled-coil protein (DUF2205) DUF2968 PF11180.3 ETO01126.1 - 2.4 7.5 20.9 5.7 6.2 9.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) EMP24_GP25L PF01105.19 ETO01126.1 - 2.5 7.7 14.6 1 9.0 4.9 2.8 1 1 2 3 3 3 0 emp24/gp25L/p24 family/GOLD LpxB PF02684.10 ETO01126.1 - 2.6 6.6 8.6 0.17 10.4 2.1 1.7 1 1 1 2 2 2 0 Lipid-A-disaccharide synthetase DUF4201 PF13870.1 ETO01126.1 - 2.7 7.3 28.8 0.92 8.9 14.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Cellulose_synt PF03552.9 ETO01126.1 - 2.9 6.0 6.8 3.6 5.7 4.7 1.0 1 0 0 1 1 1 0 Cellulose synthase Cauli_AT PF03233.8 ETO01126.1 - 3.1 7.4 17.7 0.038 13.7 3.1 2.2 1 1 1 2 2 2 0 Aphid transmission protein DUF1515 PF07439.6 ETO01126.1 - 3.1 7.6 11.8 0.27 11.0 0.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) LOH1CR12 PF10158.4 ETO01126.1 - 3.4 7.4 10.8 2.7 7.8 2.0 2.4 1 1 1 2 2 2 0 Tumour suppressor protein FlxA PF14282.1 ETO01126.1 - 4.1 7.4 31.9 0.042 13.7 7.0 2.7 1 1 0 2 2 2 0 FlxA-like protein Adeno_PIX PF03955.9 ETO01126.1 - 4.4 7.8 9.6 1.8 9.1 0.7 2.5 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) DUF4200 PF13863.1 ETO01126.1 - 4.5 7.2 34.9 0.018 14.9 10.3 2.8 1 1 2 3 3 2 0 Domain of unknown function (DUF4200) Exonuc_VII_L PF02601.10 ETO01126.1 - 5.4 6.1 18.2 6.5 5.8 12.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMF_TATA_bd PF12325.3 ETO01126.1 - 5.4 6.7 26.5 2.4 7.9 4.7 3.6 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Sigma70_ner PF04546.8 ETO01126.1 - 5.7 6.4 19.9 1.5 8.3 11.3 1.7 1 1 1 2 2 2 0 Sigma-70, non-essential region BLOC1_2 PF10046.4 ETO01126.1 - 6 7.0 19.0 1.7 8.8 0.7 3.4 1 1 3 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2203 PF09969.4 ETO01126.1 - 8.2 6.6 15.7 39 4.4 4.9 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Tox-ODYAM1 PF15642.1 ETO01126.1 - 8.2 4.9 14.8 4.2 5.9 8.6 1.7 1 1 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Mnd1 PF03962.10 ETO01126.1 - 8.3 6.0 27.2 0.056 13.1 3.8 2.1 1 1 1 2 2 2 0 Mnd1 family Ras PF00071.17 ETO01127.1 - 0.11 11.8 0.1 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Ras family DUF3136 PF11334.3 ETO01127.1 - 0.13 11.6 0.0 0.44 10.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3136) TPR_12 PF13424.1 ETO01128.1 - 6.7e-39 131.6 0.4 3.5e-22 78.1 0.1 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO01128.1 - 1.2e-21 76.0 3.9 3.2e-13 49.1 0.4 2.0 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETO01128.1 - 4.4e-17 60.8 6.3 7.2e-09 34.8 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO01128.1 - 1.8e-16 59.4 0.0 5.9e-08 32.3 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO01128.1 - 3.6e-16 57.5 1.4 2.1e-07 30.2 0.0 2.4 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO01128.1 - 7e-15 53.6 11.5 6e-08 31.9 1.0 2.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO01128.1 - 7.4e-13 47.3 2.3 1.2e-05 24.8 0.1 2.5 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO01128.1 - 1.7e-08 33.9 0.4 0.00043 20.2 0.0 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_3 PF07720.7 ETO01128.1 - 2e-06 27.4 1.2 0.039 13.7 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.13 ETO01128.1 - 8.9e-06 25.4 2.4 0.019 14.8 0.2 2.1 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain TPR_16 PF13432.1 ETO01128.1 - 9.4e-06 26.1 0.0 2.3e-05 24.9 0.0 1.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO01128.1 - 1.3e-05 25.3 0.0 0.21 12.3 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO01128.1 - 4.4e-05 23.6 0.1 0.47 11.0 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat PPR PF01535.15 ETO01128.1 - 0.0001 22.0 3.0 0.017 15.0 0.0 2.4 3 0 0 3 3 2 2 PPR repeat Apc3 PF12895.2 ETO01128.1 - 0.00022 21.3 0.3 0.0003 20.8 0.2 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO01128.1 - 0.001 19.3 0.1 0.0023 18.2 0.1 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO01128.1 - 0.0066 15.6 0.0 0.79 9.0 0.0 2.3 2 0 0 2 2 2 1 SHNi-TPR SNAP PF14938.1 ETO01128.1 - 0.0082 15.3 2.1 0.07 12.2 1.4 1.9 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP ATP-synt_E_2 PF08112.6 ETO01128.1 - 0.014 15.4 0.8 2.7 8.1 0.1 2.3 2 0 0 2 2 2 0 ATP synthase epsilon subunit Clathrin PF00637.15 ETO01128.1 - 0.02 14.4 0.2 2.6 7.6 0.0 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS TPR_5 PF12688.2 ETO01128.1 - 0.035 14.1 0.0 6.8 6.7 0.0 2.1 1 1 1 2 2 2 0 Tetratrico peptide repeat Sel1 PF08238.7 ETO01128.1 - 0.038 14.6 3.2 5 7.8 0.1 2.5 3 0 0 3 3 2 0 Sel1 repeat PPR_2 PF13041.1 ETO01128.1 - 0.046 13.6 0.6 3.7 7.5 0.0 2.4 3 0 0 3 3 2 0 PPR repeat family Ten1_2 PF15490.1 ETO01128.1 - 0.081 12.5 0.0 1.6 8.3 0.0 2.0 1 1 1 2 2 2 0 Telomere-capping, CST complex subunit SERTA PF06031.8 ETO01128.1 - 0.098 11.9 0.1 3.6 6.9 0.0 2.1 2 0 0 2 2 2 0 SERTA motif DUF3922 PF13059.1 ETO01128.1 - 0.17 12.0 1.1 11 6.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3992) DUF627 PF04781.7 ETO01128.1 - 0.25 10.9 1.6 1.9 8.1 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF627) Sec5 PF15469.1 ETO01128.1 - 0.3 10.7 1.6 0.9 9.2 1.1 1.6 1 1 0 1 1 1 0 Exocyst complex component Sec5 Ubiq-assoc PF09145.5 ETO01128.1 - 0.34 10.8 2.6 5.5 6.9 0.1 2.5 2 1 0 2 2 2 0 Ubiquitin-associated Cnd1 PF12717.2 ETO01129.1 - 0.019 14.8 0.7 0.051 13.4 0.4 1.8 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 DUF3698 PF12479.3 ETO01129.1 - 0.026 14.6 0.3 3.9 7.6 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3698) ATP-synt_F6 PF05511.6 ETO01129.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 BAF1_ABF1 PF04684.8 ETO01130.1 - 0.0083 15.0 3.2 0.0083 15.0 2.2 1.5 2 0 0 2 2 2 1 BAF1 / ABF1 chromatin reorganising factor PAP1 PF08601.5 ETO01130.1 - 8.3 5.9 35.5 0.19 11.3 18.2 2.0 2 0 0 2 2 2 0 Transcription factor PAP1 MIT PF04212.13 ETO01131.1 - 0.21 11.5 3.7 4.5 7.2 0.2 3.2 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain ASFV_p27 PF06556.6 ETO01132.1 - 0.021 14.6 0.2 0.025 14.4 0.1 1.1 1 0 0 1 1 1 0 IAP-like protein p27 C-terminus HEAT_2 PF13646.1 ETO01133.1 - 6.2e-17 61.6 0.0 6.5e-07 29.5 0.0 5.7 4 2 2 7 7 7 4 HEAT repeats HEAT PF02985.17 ETO01133.1 - 7.8e-17 59.7 0.9 0.013 15.5 0.0 6.7 7 0 0 7 7 7 4 HEAT repeat HEAT_EZ PF13513.1 ETO01133.1 - 4.7e-14 52.3 0.0 0.065 13.7 0.0 6.4 5 2 3 8 8 8 4 HEAT-like repeat Vac14_Fab1_bd PF12755.2 ETO01133.1 - 1.7e-07 31.4 2.9 0.14 12.5 0.0 4.7 2 2 2 4 4 4 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 ETO01133.1 - 6.1e-07 29.4 23.1 0.0025 17.6 1.4 5.6 1 1 3 4 4 4 2 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 ETO01133.1 - 0.0041 16.9 0.3 2.1 8.3 0.0 4.5 5 1 0 5 5 5 1 Protein of unknown function (DUF2435) Inhibitor_I9 PF05922.11 ETO01133.1 - 0.059 13.9 0.0 62 4.2 0.0 4.2 4 0 0 4 4 4 0 Peptidase inhibitor I9 MgtE_N PF03448.12 ETO01133.1 - 0.071 13.4 1.5 22 5.4 0.0 3.2 3 0 0 3 3 3 0 MgtE intracellular N domain Fringe PF02434.11 ETO01135.1 - 0.021 14.0 0.1 0.029 13.5 0.1 1.2 1 0 0 1 1 1 0 Fringe-like Mcm10 PF09332.6 ETO01135.1 - 0.57 9.4 8.4 0.84 8.9 5.8 1.5 1 1 0 1 1 1 0 Mcm10 replication factor Actin PF00022.14 ETO01136.1 - 1.8e-60 204.4 0.0 4.2e-60 203.2 0.0 1.5 1 1 0 1 1 1 1 Actin WD40 PF00400.27 ETO01137.1 - 2.1e-11 43.2 0.8 1.7e-10 40.3 0.0 2.3 3 0 0 3 3 3 1 WD domain, G-beta repeat PPR_2 PF13041.1 ETO01138.1 - 3.4e-11 42.9 6.1 0.0018 18.1 0.0 4.1 3 1 1 4 4 4 3 PPR repeat family PPR PF01535.15 ETO01138.1 - 3.9e-11 42.1 4.7 0.0095 15.8 0.0 5.2 4 0 0 4 4 4 4 PPR repeat PPR_3 PF13812.1 ETO01138.1 - 4.7e-06 26.4 0.0 0.58 10.5 0.0 5.1 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR_1 PF12854.2 ETO01138.1 - 1.5e-05 24.3 0.5 0.4 10.1 0.0 3.5 3 0 0 3 3 3 2 PPR repeat ATP13 PF12921.2 ETO01138.1 - 0.015 14.6 1.3 0.061 12.6 0.1 2.5 2 1 0 2 2 2 0 Mitochondrial ATPase expression Gp58 PF07902.6 ETO01139.1 - 0.0016 16.7 6.0 0.0019 16.4 4.1 1.0 1 0 0 1 1 1 1 gp58-like protein Muted PF14942.1 ETO01139.1 - 0.0075 16.1 3.8 0.0075 16.1 2.6 1.7 2 0 0 2 2 2 1 Organelle biogenesis, Muted-like protein Lipoprotein_3 PF00938.12 ETO01139.1 - 0.098 12.4 10.1 0.27 11.0 3.5 2.6 1 1 0 2 2 2 0 Lipoprotein Actin PF00022.14 ETO01140.1 - 6.2e-25 87.4 0.1 7.2e-25 87.2 0.0 1.0 1 0 0 1 1 1 1 Actin Kelch_1 PF01344.20 ETO01141.1 - 6.8e-08 31.9 9.7 1.2e-05 24.7 1.6 4.4 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 ETO01141.1 - 1e-05 25.5 7.1 0.17 12.0 0.7 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 ETO01141.1 - 0.00038 20.3 3.9 0.027 14.4 0.9 4.2 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.1 ETO01141.1 - 0.0013 18.8 0.3 0.072 13.2 0.0 3.4 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO01141.1 - 0.0018 17.9 12.2 0.3 10.9 1.1 5.0 5 2 0 5 5 5 1 Kelch motif Kelch_4 PF13418.1 ETO01141.1 - 0.036 13.8 6.2 4.8 7.0 0.0 4.0 3 2 1 4 4 4 0 Galactose oxidase, central domain MVL PF12151.3 ETO01141.1 - 0.11 12.2 0.4 0.27 10.9 0.2 1.6 1 0 0 1 1 1 0 Mannan-binding protein IncA PF04156.9 ETO01142.1 - 0.0013 18.3 32.5 0.0022 17.6 11.7 2.1 1 1 1 2 2 2 2 IncA protein TMF_TATA_bd PF12325.3 ETO01142.1 - 0.11 12.2 24.5 4.2 7.1 1.5 3.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.7 ETO01142.1 - 0.25 11.1 13.0 3.2 7.5 4.6 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2431 PF10354.4 ETO01142.1 - 0.44 10.4 10.5 0.083 12.8 2.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF2431) Syntaxin-6_N PF09177.6 ETO01142.1 - 1.2 9.6 18.1 4.3 7.8 3.2 3.2 1 1 2 3 3 3 0 Syntaxin 6, N-terminal TPR_MLP1_2 PF07926.7 ETO01142.1 - 1.2 8.9 32.7 0.21 11.3 5.0 3.0 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein TBPIP PF07106.8 ETO01142.1 - 1.3 8.5 28.8 1 8.9 10.4 2.7 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3584 PF12128.3 ETO01142.1 - 3.4 4.8 28.1 4.5 4.4 19.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4200 PF13863.1 ETO01142.1 - 4.1 7.3 32.8 0.37 10.7 12.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Spc7 PF08317.6 ETO01142.1 - 4.6 5.7 29.1 0.55 8.8 5.9 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein ADIP PF11559.3 ETO01142.1 - 9.3 6.1 28.4 0.97 9.3 3.1 2.7 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Ribosomal_60s PF00428.14 ETO01143.1 - 1.1e-05 25.6 9.7 1.1e-05 25.6 6.7 2.3 2 1 0 2 2 2 1 60s Acidic ribosomal protein SDA1 PF05285.7 ETO01143.1 - 2.5 7.2 8.1 3.3 6.9 5.6 1.2 1 0 0 1 1 1 0 SDA1 Prothymosin PF03247.9 ETO01143.1 - 3.3 7.8 24.4 3 8.0 0.6 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family TPR_19 PF14559.1 ETO01144.1 - 0.14 12.5 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3974 PF13120.1 ETO01145.1 - 0.6 9.9 3.8 0.36 10.6 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3974) SPARC_Ca_bdg PF10591.4 ETO01146.1 - 0.001 19.0 1.0 0.001 19.0 0.7 2.4 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region PQQ PF01011.16 ETO01146.1 - 0.34 10.5 2.4 4.6 6.9 0.0 2.9 3 0 0 3 3 3 0 PQQ enzyme repeat Spt20 PF12090.3 ETO01146.1 - 0.45 9.8 4.0 6.3 6.1 0.2 3.0 2 1 1 3 3 3 0 Spt20 family FdsD PF11390.3 ETO01149.1 - 0.096 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 NADH-dependant formate dehydrogenase delta subunit FdsD SBDS PF01172.13 ETO01150.1 - 0.0066 16.2 0.8 0.014 15.1 0.3 1.6 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein YARHG PF13308.1 ETO01150.1 - 0.019 14.4 0.6 1.4 8.4 0.1 2.3 2 0 0 2 2 2 0 YARHG domain TetR_C_8 PF14278.1 ETO01150.1 - 0.044 14.1 0.9 0.092 13.1 0.6 1.5 1 0 0 1 1 1 0 Transcriptional regulator C-terminal region Peptidase_C14 PF00656.17 ETO01151.1 - 0.0066 16.1 0.1 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Caspase domain ComC PF03047.9 ETO01151.1 - 0.022 14.1 1.7 0.054 12.9 1.1 1.7 1 0 0 1 1 1 0 COMC family WD40 PF00400.27 ETO01153.1 - 1.1e-32 110.7 12.7 4.2e-14 51.8 0.1 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO01153.1 - 4.3e-05 21.8 0.4 0.00077 17.7 0.0 2.3 2 1 1 3 3 3 1 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO01153.1 - 0.00026 20.7 0.1 0.00048 19.8 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO01153.1 - 0.00043 18.7 0.4 0.03 12.6 0.1 2.0 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO01153.1 - 0.0046 15.7 1.5 0.029 13.1 0.6 2.2 1 1 2 3 3 3 1 Nup133 N terminal like PD40 PF07676.7 ETO01153.1 - 0.019 14.6 0.5 19 5.0 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 ETO01155.1 - 4.2e-20 70.7 10.3 3.2e-09 36.3 0.4 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO01155.1 - 0.00023 19.4 2.1 0.00092 17.4 0.2 1.9 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 ETO01155.1 - 0.051 12.3 1.1 0.063 12.0 0.8 1.2 1 0 0 1 1 1 0 Coatomer WD associated region RGS PF00615.14 ETO01156.1 - 1.6e-05 24.9 0.1 3.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain Protoglobin PF11563.3 ETO01156.1 - 0.008 15.8 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Protoglobin ubiquitin PF00240.18 ETO01158.1 - 2.7e-21 74.7 0.0 3.6e-17 61.5 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 ETO01158.1 - 3.7e-10 39.3 0.0 8.4e-08 31.7 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like WD40 PF00400.27 ETO01160.1 - 2e-31 106.7 6.2 5e-10 38.8 0.1 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO01160.1 - 2.4e-07 29.2 1.7 6.1e-05 21.3 0.1 2.5 1 1 2 3 3 3 2 Nucleoporin Nup120/160 PT-HINT PF07591.6 ETO01160.1 - 0.0048 16.7 0.1 0.0089 15.9 0.1 1.4 1 0 0 1 1 1 1 Pretoxin HINT domain DUF2136 PF09907.4 ETO01160.1 - 0.063 13.3 0.1 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2136) Kelch_6 PF13964.1 ETO01160.1 - 0.097 12.8 0.3 13 6.1 0.0 3.2 2 1 1 3 3 3 0 Kelch motif Aminotran_5 PF00266.14 ETO01162.1 - 1.6e-23 83.0 0.2 2.8e-23 82.2 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Neur_chan_memb PF02932.11 ETO01162.1 - 3.5 7.4 9.9 1.3e+02 2.3 6.9 2.3 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hom_end_hint PF05203.11 ETO01163.1 - 0.014 15.1 0.8 0.016 14.9 0.6 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint Ank_5 PF13857.1 ETO01163.1 - 0.05 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO01163.1 - 0.097 13.0 0.0 0.35 11.2 0.0 1.5 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO01163.1 - 0.12 12.9 0.1 0.28 11.7 0.0 1.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO01163.1 - 0.12 12.7 0.2 0.3 11.4 0.1 1.8 1 1 0 1 1 1 0 Ankyrin repeat Mucin PF01456.12 ETO01163.1 - 3.7 7.3 18.4 4.8 6.9 12.7 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein WD40 PF00400.27 ETO01164.1 - 3.7e-06 26.5 0.3 0.0003 20.5 0.2 2.5 3 0 0 3 3 3 2 WD domain, G-beta repeat Dna2 PF08696.6 ETO01165.1 - 2.3e-14 53.2 0.1 3.6e-14 52.5 0.1 1.3 1 0 0 1 1 1 1 DNA replication factor Dna2 PDDEXK_1 PF12705.2 ETO01165.1 - 0.0037 16.6 0.0 0.0044 16.4 0.0 1.3 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.12 ETO01165.1 - 0.041 13.8 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF83 WD40 PF00400.27 ETO01166.1 - 3.1e-21 74.3 5.4 1.4e-10 40.6 0.2 2.6 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO01166.1 - 1.3e-06 26.9 0.7 0.00059 18.1 0.1 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 CH PF00307.26 ETO01169.1 - 0.00024 21.1 0.6 0.00024 21.1 0.4 1.7 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 ETO01169.1 - 0.002 17.7 0.1 0.0047 16.5 0.1 1.5 1 0 0 1 1 1 1 CAMSAP CH domain Sld5 PF05916.6 ETO01169.1 - 0.012 15.8 0.8 0.53 10.5 0.1 2.2 2 0 0 2 2 2 0 GINS complex protein DUF3533 PF12051.3 ETO01171.1 - 0.029 13.1 1.0 0.037 12.7 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3533) RelA_SpoT PF04607.12 ETO01173.1 - 0.025 14.6 0.2 0.059 13.3 0.0 1.7 2 0 0 2 2 2 0 Region found in RelA / SpoT proteins TFIIE_beta PF02186.10 ETO01173.1 - 0.19 11.7 1.4 5.2 7.1 0.0 2.6 2 1 0 2 2 2 0 TFIIE beta subunit core domain HSP70 PF00012.15 ETO01175.1 - 1.4e-43 148.7 3.0 5.8e-24 83.9 0.1 3.0 2 1 1 3 3 3 3 Hsp70 protein DUF3964 PF13107.1 ETO01175.1 - 0.02 15.1 0.1 0.055 13.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3964) DUF3713 PF12506.3 ETO01176.1 - 0.092 12.8 0.4 0.092 12.8 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) TatD_DNase PF01026.16 ETO01178.1 - 3.7e-30 104.9 0.1 4.8e-30 104.5 0.1 1.1 1 0 0 1 1 1 1 TatD related DNase Ste50p-SAM PF09235.5 ETO01180.1 - 3.8e-06 26.8 3.8 2.6e-05 24.1 0.2 2.7 1 1 1 2 2 2 1 Ste50p, sterile alpha motif TUG-UBL1 PF11470.3 ETO01180.1 - 0.00037 20.3 0.1 0.0015 18.4 0.0 2.0 2 0 0 2 2 2 1 GLUT4 regulating protein TUG ubiquitin PF00240.18 ETO01180.1 - 0.032 13.6 0.2 0.25 10.7 0.0 2.4 3 0 0 3 3 3 0 Ubiquitin family SapB_1 PF05184.10 ETO01180.1 - 6.2 6.7 7.4 19 5.1 0.4 3.5 3 0 0 3 3 3 0 Saposin-like type B, region 1 Kelch_6 PF13964.1 ETO01181.1 - 0.093 12.9 0.1 0.34 11.1 0.1 1.9 1 0 0 1 1 1 0 Kelch motif Kelch_1 PF01344.20 ETO01181.1 - 1.1 8.8 5.7 0.4 10.2 0.2 2.8 4 0 0 4 4 4 0 Kelch motif AgrB PF04647.10 ETO01182.1 - 0.028 13.4 0.8 0.07 12.1 0.6 1.6 1 0 0 1 1 1 0 Accessory gene regulator B IBR PF01485.16 ETO01182.1 - 1.8 8.4 26.3 15 5.5 14.8 3.7 1 1 1 2 2 2 0 IBR domain UCH PF00443.24 ETO01183.1 - 5.8e-08 32.1 0.0 5.8e-08 32.1 0.0 1.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF2232 PF09991.4 ETO01183.1 - 0.12 11.3 2.4 0.16 10.9 1.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF4010 PF13194.1 ETO01184.1 - 0.0051 16.1 0.0 0.0067 15.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4010) DUF3099 PF11298.3 ETO01184.1 - 0.022 14.4 1.5 0.048 13.4 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) Tic20 PF09685.5 ETO01184.1 - 0.28 11.1 4.2 0.49 10.4 2.9 1.4 1 0 0 1 1 1 0 Tic20-like protein DUF4014 PF13198.1 ETO01186.1 - 0.0077 16.6 0.2 0.014 15.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4014) Ribonuc_red_2_N PF08471.5 ETO01186.1 - 0.16 12.0 0.3 2.1 8.4 0.0 2.2 2 1 0 2 2 2 0 Class II vitamin B12-dependent ribonucleotide reductase VWA_2 PF13519.1 ETO01187.1 - 1.6e-05 25.0 0.0 2e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 ETO01187.1 - 0.0017 18.2 0.0 0.0027 17.5 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.23 ETO01187.1 - 0.024 14.3 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain iPGM_N PF06415.8 ETO01187.1 - 0.041 13.2 0.0 0.11 11.8 0.0 1.6 2 0 0 2 2 2 0 BPG-independent PGAM N-terminus (iPGM_N) RXT2_N PF08595.6 ETO01189.1 - 0.046 13.5 0.4 0.046 13.5 0.3 1.5 2 0 0 2 2 2 0 RXT2-like, N-terminal Glyco_hyd_65N_2 PF14498.1 ETO01189.1 - 0.12 11.9 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain MUG113 PF13455.1 ETO01190.1 - 0.068 13.6 0.6 0.16 12.4 0.4 1.8 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 DUF262 PF03235.9 ETO01190.1 - 0.072 13.0 5.8 0.085 12.8 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 DUF912 PF06024.7 ETO01190.1 - 0.21 11.6 4.2 0.34 10.9 2.9 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TPR_12 PF13424.1 ETO01191.1 - 1.1e-40 137.4 10.5 7.1e-24 83.5 1.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO01191.1 - 4.8e-24 82.9 14.8 3.8e-09 35.7 0.8 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO01191.1 - 5.5e-22 76.9 0.2 6.5e-09 35.4 0.0 3.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO01191.1 - 1.3e-19 68.3 4.6 7.2e-07 28.5 0.1 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO01191.1 - 1.6e-17 61.9 11.0 1.7e-06 27.5 0.2 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO01191.1 - 1.1e-16 60.2 9.6 3.5e-14 52.1 1.9 2.3 1 1 0 2 2 2 2 TPR repeat TPR_8 PF13181.1 ETO01191.1 - 5.4e-16 57.1 15.1 7.1e-07 28.5 0.5 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO01191.1 - 5.7e-12 44.8 4.3 0.0018 18.3 0.1 3.7 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO01191.1 - 5.8e-07 29.5 0.7 0.15 12.5 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO01191.1 - 1.1e-06 28.7 0.0 0.15 12.7 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO01191.1 - 3.8e-05 24.2 0.2 0.61 10.8 0.0 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.13 ETO01191.1 - 6e-05 22.8 10.3 0.1 12.4 0.2 3.1 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.1 ETO01191.1 - 0.0036 17.1 7.1 0.42 10.5 0.3 3.0 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat Apc3 PF12895.2 ETO01191.1 - 0.011 15.8 1.9 0.056 13.5 0.8 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Spc24 PF08286.6 ETO01191.1 - 0.011 15.4 2.3 0.71 9.5 0.2 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 SNAP PF14938.1 ETO01191.1 - 0.012 14.8 2.0 0.084 12.0 0.2 1.6 1 1 1 2 2 2 0 Soluble NSF attachment protein, SNAP RPN7 PF10602.4 ETO01191.1 - 0.029 13.7 0.4 0.036 13.4 0.3 1.2 1 0 0 1 1 1 0 26S proteasome subunit RPN7 DUF2225 PF09986.4 ETO01191.1 - 0.033 13.6 0.4 0.046 13.1 0.3 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_5 PF12688.2 ETO01191.1 - 0.05 13.6 0.1 0.3 11.1 0.1 2.0 1 1 1 2 2 2 0 Tetratrico peptide repeat Sel1 PF08238.7 ETO01191.1 - 0.12 13.0 7.3 3.5 8.4 0.1 3.3 3 0 0 3 3 3 0 Sel1 repeat DUF386 PF04074.7 ETO01191.1 - 0.15 11.5 3.0 0.17 11.3 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF386) TPR_19 PF14559.1 ETO01191.1 - 0.21 11.9 1.9 1.2 9.5 0.1 2.5 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.7 ETO01191.1 - 0.83 9.5 10.0 4.1 7.3 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Ubiq-assoc PF09145.5 ETO01191.1 - 6.1 6.7 8.6 9.5 6.1 0.3 4.2 3 3 1 4 4 4 0 Ubiquitin-associated DUF3402 PF11882.3 ETO01192.1 - 4.1e-19 68.9 14.9 6.6e-15 55.0 3.9 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF3402) DUF4184 PF13803.1 ETO01192.1 - 0.078 12.2 0.5 0.35 10.1 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4184) Neur_chan_memb PF02932.11 ETO01192.1 - 4.9 6.9 9.5 22 4.8 0.2 2.7 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region FLO_LFY PF01698.11 ETO01193.1 - 0.28 10.0 6.3 0.36 9.6 4.4 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein TFIIF_alpha PF05793.7 ETO01193.1 - 1.6 7.0 17.9 2.1 6.6 12.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3537 PF12056.3 ETO01193.1 - 1.8 7.1 4.7 2.8 6.5 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) UPF0546 PF10639.4 ETO01194.1 - 0.11 12.3 3.3 1.2 8.9 0.2 2.4 1 1 1 2 2 2 0 Uncharacterised protein family UPF0546 zf-TRAF PF02176.13 ETO01195.1 - 4.1e-06 27.0 9.4 1.3e-05 25.4 5.7 2.6 1 1 0 1 1 1 1 TRAF-type zinc finger Med3 PF11593.3 ETO01196.1 - 2.6 7.2 30.2 3.3 6.8 20.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Peptidase_S64 PF08192.6 ETO01196.1 - 5.3 5.2 20.9 5.7 5.1 14.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 Utp14 PF04615.8 ETO01196.1 - 6 4.9 21.1 6.9 4.7 14.6 1.1 1 0 0 1 1 1 0 Utp14 protein Kelch_1 PF01344.20 ETO01197.1 - 7.8e-05 22.1 3.6 0.0043 16.5 1.1 2.6 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 ETO01197.1 - 0.0066 16.2 0.1 0.22 11.3 0.0 2.6 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO01197.1 - 0.024 14.8 0.2 0.54 10.5 0.1 2.5 1 1 1 2 2 2 0 Kelch motif Kelch_5 PF13854.1 ETO01197.1 - 0.22 11.5 3.0 0.28 11.2 0.5 2.3 3 0 0 3 3 3 0 Kelch motif RD3 PF14473.1 ETO01202.1 - 0.067 12.6 0.4 0.071 12.5 0.3 1.1 1 0 0 1 1 1 0 RD3 protein SR-25 PF10500.4 ETO01203.1 - 1.2e-05 24.9 19.5 1.7e-05 24.4 13.5 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Dicty_REP PF05086.7 ETO01203.1 - 0.0039 15.0 5.3 0.0042 14.9 3.7 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Med19 PF10278.4 ETO01203.1 - 0.0047 16.6 18.6 0.0094 15.6 12.9 1.5 1 0 0 1 1 1 1 Mediator of RNA pol II transcription subunit 19 DUF572 PF04502.8 ETO01203.1 - 0.019 14.2 13.1 0.021 14.0 9.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2052 PF09747.4 ETO01203.1 - 0.03 14.2 14.1 0.051 13.4 9.7 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF3513 PF12026.3 ETO01203.1 - 0.04 13.4 12.8 0.69 9.4 7.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3513) DUF966 PF06136.8 ETO01203.1 - 0.053 12.9 10.6 0.067 12.6 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF1777 PF08648.7 ETO01203.1 - 0.083 12.6 13.3 0.12 12.0 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DUF2201_N PF13203.1 ETO01203.1 - 0.085 12.0 6.8 0.11 11.6 4.7 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DDHD PF02862.12 ETO01203.1 - 0.15 11.7 10.5 0.2 11.4 7.3 1.3 1 0 0 1 1 1 0 DDHD domain Pox_Ag35 PF03286.9 ETO01203.1 - 0.23 10.9 19.3 0.78 9.2 13.4 1.8 1 1 0 1 1 1 0 Pox virus Ag35 surface protein GAGA_bind PF06217.7 ETO01203.1 - 0.24 11.3 11.8 0.28 11.1 8.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Cellulose_synt PF03552.9 ETO01203.1 - 0.29 9.3 1.3 0.3 9.3 0.9 1.1 1 0 0 1 1 1 0 Cellulose synthase Daxx PF03344.10 ETO01203.1 - 0.39 9.1 17.8 0.48 8.8 12.4 1.1 1 0 0 1 1 1 0 Daxx Family Hid1 PF12722.2 ETO01203.1 - 0.41 8.2 10.6 0.46 8.0 7.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.7 ETO01203.1 - 0.45 10.3 18.6 0.67 9.8 12.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.12 ETO01203.1 - 0.66 8.7 11.1 0.86 8.3 7.7 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.11 ETO01203.1 - 1.1 9.1 5.4 1.3 8.8 3.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SID-1_RNA_chan PF13965.1 ETO01203.1 - 1.1 7.3 4.3 1.6 6.8 3.0 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SAPS PF04499.10 ETO01203.1 - 1.3 7.5 12.6 1.8 7.0 8.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NPR3 PF03666.8 ETO01203.1 - 1.5 7.2 16.9 2.2 6.7 11.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MIP-T3 PF10243.4 ETO01203.1 - 1.5 7.1 28.6 0.89 7.9 16.6 2.0 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Ycf1 PF05758.7 ETO01203.1 - 1.7 6.2 13.1 1.9 6.0 9.1 1.1 1 0 0 1 1 1 0 Ycf1 Zip PF02535.17 ETO01203.1 - 2 7.3 5.4 2.5 7.0 3.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Otopetrin PF03189.8 ETO01203.1 - 2.8 6.8 4.7 4.2 6.2 3.2 1.2 1 0 0 1 1 1 0 Otopetrin CDC37_M PF08565.6 ETO01203.1 - 3.1 7.2 16.5 0.16 11.4 6.1 2.1 1 1 1 2 2 2 0 Cdc37 Hsp90 binding domain DUF1510 PF07423.6 ETO01203.1 - 3.1 7.0 25.0 4.6 6.5 17.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DHHW PF14286.1 ETO01203.1 - 3.6 6.8 12.6 5.8 6.1 8.8 1.3 1 0 0 1 1 1 0 DHHW protein DUF913 PF06025.7 ETO01203.1 - 3.7 6.1 8.5 4.9 5.8 5.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) BLVR PF06375.6 ETO01203.1 - 7.3 6.4 26.5 24 4.7 18.4 1.8 1 1 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) WD40 PF00400.27 ETO01204.1 - 0.008 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 WD domain, G-beta repeat Geminin PF07412.7 ETO01204.1 - 0.01 15.5 5.4 0.01 15.5 3.8 3.1 2 1 1 3 3 3 0 Geminin Macoilin PF09726.4 ETO01204.1 - 0.11 10.7 21.4 0.12 10.6 14.9 1.0 1 0 0 1 1 1 0 Transmembrane protein TPR_MLP1_2 PF07926.7 ETO01204.1 - 0.12 12.0 26.8 0.49 10.1 5.1 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein TBPIP PF07106.8 ETO01204.1 - 0.14 11.7 24.4 0.18 11.3 16.9 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Vfa1 PF08432.5 ETO01204.1 - 0.16 12.0 23.0 0.021 14.8 11.8 1.8 1 1 1 2 2 2 0 AAA-ATPase Vps4-associated protein 1 TMEM237 PF15383.1 ETO01204.1 - 0.16 11.0 8.8 0.2 10.7 6.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 237 DUF4055 PF13264.1 ETO01204.1 - 0.23 11.5 3.1 0.28 11.2 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) Atg14 PF10186.4 ETO01204.1 - 0.59 9.0 20.5 0.68 8.8 14.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 GCD14 PF08704.5 ETO01204.1 - 0.61 9.5 8.1 0.75 9.2 5.6 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DUF3584 PF12128.3 ETO01204.1 - 1.2 6.4 20.8 1.3 6.3 14.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF641 PF04859.7 ETO01204.1 - 1.9 8.2 22.4 1.6 8.5 2.5 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF4473 PF14747.1 ETO01204.1 - 2 8.6 17.2 3.2 8.0 2.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) DUF4200 PF13863.1 ETO01204.1 - 3.8 7.4 32.4 2.2 8.2 3.8 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF2968 PF11180.3 ETO01204.1 - 3.8 6.8 18.9 1.5 8.1 9.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Rootletin PF15035.1 ETO01204.1 - 9.8 6.1 21.5 1.4e+02 2.3 14.8 2.3 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion eRF1_1 PF03463.10 ETO01205.1 - 6.2e-08 32.2 0.2 8.8e-08 31.8 0.1 1.2 1 0 0 1 1 1 1 eRF1 domain 1 Mito_carr PF00153.22 ETO01206.1 - 7.2e-42 141.0 0.1 1e-13 50.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein OST3_OST6 PF04756.8 ETO01207.1 - 0.5 9.9 6.4 0.85 9.1 4.4 1.4 1 1 0 1 1 1 0 OST3 / OST6 family zf-TRAF PF02176.13 ETO01208.1 - 0.00013 22.2 3.6 0.00013 22.2 2.5 2.7 3 1 1 4 4 4 1 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 ETO01208.1 - 0.83 9.7 11.2 0.11 12.5 0.9 3.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Orbi_VP2 PF00898.12 ETO01211.1 - 0.043 11.3 0.3 0.045 11.3 0.2 1.0 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP2 WD40 PF00400.27 ETO01212.1 - 8.3e-09 34.9 0.7 1.3e-08 34.4 0.5 1.4 1 0 0 1 1 1 1 WD domain, G-beta repeat Ank_4 PF13637.1 ETO01213.1 - 2.5e-05 24.6 0.1 0.00061 20.2 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO01213.1 - 0.00012 21.9 1.1 0.023 14.9 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 ETO01213.1 - 0.00055 20.2 0.1 0.001 19.3 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO01213.1 - 0.015 15.0 0.9 0.28 11.0 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat ATS PF15445.1 ETO01214.1 - 0.022 13.8 0.5 0.025 13.7 0.4 1.0 1 0 0 1 1 1 0 acidic terminal segments, variant surface antigen of PfEMP1 DUF4628 PF15429.1 ETO01214.1 - 0.029 13.7 0.3 0.032 13.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) RecR PF02132.10 ETO01215.1 - 0.058 12.8 1.5 0.14 11.6 0.0 2.3 2 0 0 2 2 2 0 RecR protein DUF4344 PF14247.1 ETO01216.1 - 0.043 13.4 0.1 0.059 13.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4344) Kelch_1 PF01344.20 ETO01217.1 - 0.096 12.2 0.1 16 5.1 0.0 3.4 3 0 0 3 3 3 0 Kelch motif WD40 PF00400.27 ETO01221.1 - 9.4e-10 37.9 0.0 6.2e-08 32.2 0.0 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF1664 PF07889.7 ETO01222.1 - 0.0014 18.4 3.8 0.0017 18.1 2.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) DUF241 PF03087.9 ETO01222.1 - 0.0039 16.7 3.0 0.0048 16.4 2.1 1.1 1 0 0 1 1 1 1 Arabidopsis protein of unknown function Phlebovirus_NSM PF07246.6 ETO01222.1 - 0.021 14.0 3.8 0.027 13.6 2.7 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF3573 PF12097.3 ETO01222.1 - 0.023 13.3 4.6 0.023 13.3 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) AAA_13 PF13166.1 ETO01222.1 - 0.024 13.1 8.6 0.024 13.0 6.0 1.0 1 0 0 1 1 1 0 AAA domain Mito_fiss_reg PF05308.6 ETO01222.1 - 0.032 13.6 6.6 0.035 13.4 4.6 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Med3 PF11593.3 ETO01222.1 - 0.034 13.3 6.7 0.022 13.9 3.7 1.3 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal Suf PF05843.9 ETO01222.1 - 0.06 13.0 8.5 0.066 12.9 5.9 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Atg14 PF10186.4 ETO01222.1 - 0.068 12.1 8.9 0.074 11.9 6.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3450 PF11932.3 ETO01222.1 - 0.072 12.3 13.8 0.088 12.0 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CorA PF01544.13 ETO01222.1 - 0.098 11.6 5.6 0.11 11.5 3.9 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF812 PF05667.6 ETO01222.1 - 0.12 10.8 12.0 0.13 10.7 8.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Syntaxin PF00804.20 ETO01222.1 - 0.12 12.5 13.5 0.17 12.0 9.0 1.5 1 1 1 2 2 2 0 Syntaxin DUF948 PF06103.6 ETO01222.1 - 0.13 12.1 4.5 0.17 11.7 3.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF4613 PF15390.1 ETO01222.1 - 0.13 10.3 3.9 0.15 10.1 2.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) BLOC1_2 PF10046.4 ETO01222.1 - 0.15 12.2 8.8 0.33 11.1 5.2 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4407 PF14362.1 ETO01222.1 - 0.3 10.0 8.7 0.33 9.8 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Trypan_glycop_C PF10659.4 ETO01222.1 - 0.34 11.2 4.5 0.31 11.3 2.5 1.4 1 1 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain bZIP_2 PF07716.10 ETO01222.1 - 0.66 9.8 7.4 3.2 7.6 5.1 2.3 1 1 0 1 1 1 0 Basic region leucine zipper DUF935 PF06074.7 ETO01222.1 - 0.71 8.5 8.0 0.82 8.3 5.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Pox_Ag35 PF03286.9 ETO01222.1 - 0.75 9.2 12.2 0.45 10.0 6.5 1.6 1 1 0 1 1 1 0 Pox virus Ag35 surface protein Mnd1 PF03962.10 ETO01222.1 - 0.85 9.2 13.4 1 8.9 9.3 1.1 1 0 0 1 1 1 0 Mnd1 family FliD_N PF02465.13 ETO01222.1 - 1.1 9.6 8.1 1.4 9.2 4.9 1.9 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus FlaC_arch PF05377.6 ETO01222.1 - 1.5 8.7 5.2 2 8.3 2.1 2.1 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF4094 PF13334.1 ETO01222.1 - 1.7 9.0 9.6 2.9 8.3 6.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) EURL PF06937.6 ETO01222.1 - 1.9 7.8 8.6 2.3 7.5 6.0 1.1 1 0 0 1 1 1 0 EURL protein DUF4140 PF13600.1 ETO01222.1 - 1.9 8.9 7.7 3.3 8.2 5.0 1.7 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF4557 PF15101.1 ETO01222.1 - 1.9 8.2 7.5 2.2 8.1 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF2201_N PF13203.1 ETO01222.1 - 1.9 7.5 7.6 2.2 7.4 5.2 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DARPP-32 PF05395.7 ETO01222.1 - 2 8.5 12.8 0.31 11.1 5.7 1.7 1 1 1 2 2 2 0 Protein phosphatase inhibitor 1/DARPP-32 Pex14_N PF04695.8 ETO01222.1 - 2.6 8.0 7.3 3.2 7.7 5.1 1.3 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2203 PF09969.4 ETO01222.1 - 3.2 8.0 6.0 4.1 7.6 4.0 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) IncA PF04156.9 ETO01222.1 - 4.6 6.7 16.5 6.5 6.3 11.4 1.3 1 1 0 1 1 1 0 IncA protein RRN3 PF05327.6 ETO01222.1 - 4.8 5.1 9.8 5.4 4.9 6.8 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DivIC PF04977.10 ETO01222.1 - 7.2 6.1 13.6 5 6.6 7.5 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF972 PF06156.8 ETO01222.1 - 8.1 6.8 11.7 18 5.6 7.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) APG6 PF04111.7 ETO01222.1 - 8.6 5.3 13.9 10 5.0 9.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2919 PF11143.3 ETO01223.1 - 0.41 10.4 3.0 9.9 5.9 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2919) WD40 PF00400.27 ETO01224.1 - 1e-28 98.1 14.1 1.4e-08 34.2 0.0 5.6 6 0 0 6 6 6 5 WD domain, G-beta repeat SUKH_5 PF14567.1 ETO01224.1 - 0.087 12.2 0.1 0.16 11.3 0.1 1.5 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall RasGEF_N PF00618.15 ETO01225.1 - 0.23 11.5 5.4 0.64 10.1 3.8 1.8 1 1 0 1 1 1 0 RasGEF N-terminal motif Cas_CXXC_CXXC PF09706.5 ETO01227.1 - 0.008 16.3 0.3 4.3 7.5 0.0 2.7 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_CXXC_CXXC) RelA_SpoT PF04607.12 ETO01227.1 - 0.0098 15.8 0.9 0.017 15.1 0.2 1.7 2 0 0 2 2 2 1 Region found in RelA / SpoT proteins NOB1_Zn_bind PF08772.6 ETO01227.1 - 0.084 12.7 0.1 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like DNA_ligase_ZBD PF03119.11 ETO01227.1 - 0.23 11.1 2.3 3.1 7.5 0.2 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Phe_hydrox_dim PF07976.7 ETO01228.1 - 0.018 14.6 0.1 0.087 12.4 0.0 1.8 1 1 1 2 2 2 0 Phenol hydroxylase, C-terminal dimerisation domain DUF3600 PF12207.3 ETO01228.1 - 0.044 13.3 0.3 0.06 12.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3600) Plus-3 PF03126.13 ETO01228.1 - 0.045 13.7 1.2 0.1 12.6 0.8 1.6 1 1 0 1 1 1 0 Plus-3 domain MSA_2 PF00985.12 ETO01228.1 - 0.071 13.2 1.6 0.096 12.8 1.1 1.1 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family DRY_EERY PF09750.4 ETO01228.1 - 0.071 13.2 2.0 0.083 12.9 1.4 1.1 1 0 0 1 1 1 0 Alternative splicing regulator PBP_sp32 PF07222.7 ETO01228.1 - 0.23 10.5 3.6 0.29 10.2 2.5 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 TMEM220 PF15071.1 ETO01229.1 - 0.011 16.1 1.1 0.011 16.1 0.8 2.8 4 0 0 4 4 4 0 Transmembrane family 220, helix BLVR PF06375.6 ETO01229.1 - 9.5 6.0 15.1 3.5 7.4 0.7 2.2 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) ubiquitin PF00240.18 ETO01231.1 - 3.1e-60 199.4 4.3 2.6e-34 116.4 0.4 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 ETO01231.1 - 1.8e-34 117.2 2.1 6.6e-21 73.7 0.4 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 ETO01231.1 - 2.2e-11 43.8 1.0 9.6e-06 25.7 0.1 3.3 2 2 0 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 ETO01231.1 - 1.7e-07 31.0 0.1 0.0056 16.5 0.0 2.5 2 1 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 ETO01231.1 - 2e-05 24.5 0.0 0.37 10.8 0.0 2.8 2 2 1 3 3 3 2 Protein of unknown function (DUF2870) Telomere_Sde2 PF13019.1 ETO01231.1 - 2.1e-05 24.2 0.0 0.00061 19.5 0.0 2.0 2 0 0 2 2 2 1 Telomere stability and silencing DUF2407 PF10302.4 ETO01231.1 - 2.2e-05 24.5 0.1 0.039 14.1 0.0 2.2 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 ETO01231.1 - 0.0062 16.4 0.3 0.051 13.4 0.0 2.1 2 0 0 2 2 2 1 GLUT4 regulating protein TUG eRF1_1 PF03463.10 ETO01231.1 - 0.046 13.2 0.1 0.3 10.6 0.0 2.3 1 1 1 2 2 2 0 eRF1 domain 1 IGR PF09597.5 ETO01231.1 - 0.063 13.1 0.0 14 5.7 0.0 2.5 2 0 0 2 2 2 0 IGR protein motif USP7_C2 PF14533.1 ETO01231.1 - 0.066 12.6 0.2 0.13 11.6 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-specific protease C-terminal Plexin_cytopl PF08337.7 ETO01231.1 - 0.15 10.3 0.2 3.8 5.7 0.2 2.4 2 1 0 2 2 2 0 Plexin cytoplasmic RasGAP domain PUB PF09409.5 ETO01232.1 - 0.0082 15.8 0.6 0.024 14.3 0.4 1.9 1 1 0 1 1 1 1 PUB domain Viral_Rep PF02407.11 ETO01233.1 - 2.4 8.2 8.2 13 5.8 0.3 3.1 1 1 1 3 3 3 0 Putative viral replication protein Rotavirus_VP3 PF06929.6 ETO01235.1 - 0.14 9.9 3.6 0.14 9.9 2.5 1.1 1 0 0 1 1 1 0 Rotavirus VP3 protein Seryl_tRNA_N PF02403.17 ETO01235.1 - 0.45 10.5 6.0 1.5 8.9 4.1 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain AAA_24 PF13479.1 ETO01237.1 - 0.0015 18.1 0.1 0.0039 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF1911 PF08929.5 ETO01238.1 - 0.057 14.1 2.6 0.11 13.2 1.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1911) DUF3944 PF13099.1 ETO01238.1 - 0.18 11.2 0.8 0.56 9.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3944) DUF2758 PF10957.3 ETO01238.1 - 0.23 11.3 5.8 2.4 8.0 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2758) Borrelia_lipo_2 PF06238.6 ETO01239.1 - 0.073 13.1 0.8 0.098 12.7 0.6 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi BBR25 lipoprotein zf-C3HC4_2 PF13923.1 ETO01240.1 - 0.012 15.6 1.7 0.11 12.5 1.2 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO01240.1 - 2.1 8.0 5.4 21 4.8 1.1 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DNA_pol_phi PF04931.8 ETO01245.1 - 0.84 7.3 6.8 1.5 6.4 4.7 1.5 1 1 0 1 1 1 0 DNA polymerase phi DOR PF14839.1 ETO01247.1 - 0.027 14.2 7.6 0.04 13.6 5.3 1.2 1 0 0 1 1 1 0 DOR family zf-C4pol PF14260.1 ETO01247.1 - 0.063 13.2 1.7 0.063 13.2 1.2 2.6 2 2 1 3 3 3 0 C4-type zinc-finger of DNA polymerase delta U-box PF04564.10 ETO01248.1 - 2.2e-13 49.9 0.1 4.4e-13 48.9 0.0 1.5 1 1 0 1 1 1 1 U-box domain WD40 PF00400.27 ETO01250.1 - 5.7e-30 102.0 9.9 2.2e-08 33.6 0.0 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat eIF2A PF08662.6 ETO01250.1 - 6.7e-06 25.9 0.1 0.00025 20.8 0.0 2.7 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 ETO01250.1 - 2e-05 23.6 0.0 0.012 14.4 0.0 2.4 1 1 1 2 2 2 2 Coatomer WD associated region PQQ_2 PF13360.1 ETO01250.1 - 9.4e-05 21.9 0.0 0.0011 18.4 0.0 2.1 1 1 1 2 2 2 2 PQQ-like domain Cytochrom_D1 PF02239.11 ETO01250.1 - 0.0002 19.7 0.0 0.0016 16.7 0.0 1.8 1 1 1 2 2 2 2 Cytochrome D1 heme domain RicinB_lectin_2 PF14200.1 ETO01250.1 - 0.0027 18.0 0.0 2.7 8.4 0.0 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like PTB PF08416.8 ETO01250.1 - 0.0053 16.6 0.0 0.21 11.4 0.0 2.6 2 1 1 3 3 3 1 Phosphotyrosine-binding domain PD40 PF07676.7 ETO01250.1 - 0.017 14.7 0.3 12 5.7 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 ETO01250.1 - 0.034 12.7 0.0 3.3 6.1 0.0 2.5 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region TFIIIC_delta PF12657.2 ETO01250.1 - 0.045 13.4 0.7 4 7.1 0.0 2.8 1 1 1 2 2 2 0 Transcription factor IIIC subunit delta N-term Lactonase PF10282.4 ETO01250.1 - 0.046 12.8 0.1 0.16 11.0 0.0 1.8 1 1 0 1 1 1 0 Lactonase, 7-bladed beta-propeller PQQ PF01011.16 ETO01250.1 - 0.056 13.0 0.0 6.9 6.4 0.0 2.8 2 0 0 2 2 2 0 PQQ enzyme repeat Nup160 PF11715.3 ETO01250.1 - 0.087 10.9 0.3 0.14 10.3 0.2 1.4 1 1 0 1 1 1 0 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO01250.1 - 0.094 12.0 1.3 3.6 6.7 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4221) 7TM_GPCR_Srh PF10318.4 ETO01251.1 - 0.0085 14.9 4.9 0.01 14.6 3.4 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh VP7 PF00434.13 ETO01251.1 - 0.01 14.7 0.4 0.01 14.7 0.3 1.8 1 1 1 2 2 2 0 Glycoprotein VP7 TrkH PF02386.11 ETO01251.1 - 0.037 12.6 1.4 0.048 12.2 0.9 1.2 1 0 0 1 1 1 0 Cation transport protein Hema_HEFG PF02710.9 ETO01251.1 - 0.21 11.8 3.0 0.15 12.2 0.9 1.6 1 1 1 2 2 2 0 Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein ATP-synt_8 PF00895.15 ETO01251.1 - 0.29 11.3 7.6 0.3 11.3 0.4 2.7 2 1 1 3 3 3 0 ATP synthase protein 8 YoqO PF14037.1 ETO01251.1 - 1.3 9.1 9.8 0.35 10.9 1.2 2.1 1 1 0 2 2 2 0 YoqO-like protein TypeIII_RM_meth PF12564.3 ETO01251.1 - 5.4 7.0 9.8 0.1 12.5 1.2 2.2 3 0 0 3 3 3 0 Type III restriction/modification enzyme methylation subunit CENP-R PF06729.7 ETO01255.1 - 0.011 15.4 1.0 0.013 15.1 0.7 1.1 1 0 0 1 1 1 0 Kinetochore component, CENP-R DUF4163 PF13739.1 ETO01255.1 - 0.047 14.4 6.6 0.061 14.1 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4163) Menin PF05053.8 ETO01255.1 - 0.065 11.3 0.4 0.062 11.4 0.3 1.0 1 0 0 1 1 1 0 Menin Imm23 PF15593.1 ETO01255.1 - 1.8 8.7 9.3 2 8.5 6.5 1.0 1 0 0 1 1 1 0 Immunity protein 23 ThiS-like PF14453.1 ETO01255.1 - 2.4 8.0 6.8 0.4 10.5 0.4 2.6 1 1 2 3 3 3 0 ThiS-like ubiquitin Kelch_5 PF13854.1 ETO01256.1 - 2.1e-05 24.3 4.5 0.55 10.2 0.4 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 ETO01256.1 - 0.0003 20.4 5.2 0.01 15.5 0.1 4.0 4 1 1 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO01256.1 - 0.00047 19.6 3.2 0.81 9.2 0.1 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO01256.1 - 0.0017 18.0 6.0 0.64 9.8 0.3 4.4 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 ETO01256.1 - 0.0024 17.9 5.9 4 7.7 0.1 4.8 5 0 0 5 5 5 2 Kelch motif WD40 PF00400.27 ETO01258.1 - 4.8e-43 143.5 8.9 6.1e-12 44.9 0.3 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO01258.1 - 1.7e-08 33.0 0.3 0.093 10.8 0.0 3.8 1 1 2 4 4 4 4 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO01258.1 - 0.013 15.2 2.5 12 5.4 0.2 3.4 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A DUF4477 PF14780.1 ETO01259.1 - 0.037 13.4 0.1 0.067 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) HR1 PF02185.11 ETO01259.1 - 0.05 13.3 0.3 0.19 11.4 0.2 2.0 1 0 0 1 1 1 0 Hr1 repeat CbiA PF01656.18 ETO01260.1 - 4.7e-19 68.5 0.0 6.2e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 ETO01260.1 - 7.6e-11 42.1 0.1 1.4e-10 41.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 ETO01260.1 - 0.00014 21.0 0.1 0.0018 17.4 0.0 2.3 1 1 0 1 1 1 1 Anion-transporting ATPase Fer4_NifH PF00142.13 ETO01260.1 - 0.005 16.0 0.1 0.069 12.3 0.0 2.2 2 1 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.6 ETO01260.1 - 0.015 14.4 0.0 2 7.4 0.0 2.2 1 1 1 2 2 2 0 ATPase MipZ SDA1 PF05285.7 ETO01262.1 - 0.033 13.4 15.0 0.043 13.1 10.4 1.2 1 0 0 1 1 1 0 SDA1 Atrophin-1 PF03154.10 ETO01262.1 - 0.54 8.3 10.1 0.65 8.0 7.0 1.1 1 0 0 1 1 1 0 Atrophin-1 family Cellulose_synt PF03552.9 ETO01262.1 - 0.84 7.8 5.6 0.91 7.7 3.9 1.0 1 0 0 1 1 1 0 Cellulose synthase Apc3 PF12895.2 ETO01263.1 - 0.045 13.8 0.4 0.096 12.8 0.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF1443 PF07280.6 ETO01263.1 - 0.048 13.2 1.6 6.3 6.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1443) NACHT PF05729.7 ETO01264.1 - 0.0053 16.4 0.0 0.0085 15.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain TLD PF07534.11 ETO01266.1 - 0.00012 22.0 0.1 0.0015 18.5 0.0 2.4 2 1 1 3 3 3 1 TLD WD40 PF00400.27 ETO01268.1 - 4.9e-16 57.9 6.4 1.6e-11 43.6 0.9 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO01268.1 - 0.00014 20.1 0.1 0.00016 19.9 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 UN_NPL4 PF11543.3 ETO01270.1 - 0.015 15.5 0.0 0.037 14.3 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 PB1 PF00564.19 ETO01270.1 - 0.039 13.6 0.8 0.14 11.8 0.3 2.0 2 0 0 2 2 2 0 PB1 domain DUF871 PF05913.6 ETO01272.1 - 0.056 12.2 0.3 0.06 12.1 0.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF871) AAA_12 PF13087.1 ETO01273.1 - 6.9e-45 152.8 1.7 1e-44 152.3 1.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 ETO01273.1 - 2.1e-18 66.7 2.4 2.4e-18 66.5 0.0 2.1 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 ETO01273.1 - 0.00014 21.5 0.2 0.037 13.5 0.0 2.7 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 ETO01273.1 - 0.00032 20.7 0.0 0.00073 19.6 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C PF13361.1 ETO01273.1 - 0.018 14.5 2.7 0.95 8.8 0.0 2.6 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain Ric8 PF10165.4 ETO01274.1 - 0.025 13.4 0.2 0.027 13.3 0.1 1.0 1 0 0 1 1 1 0 Guanine nucleotide exchange factor synembryn Sin_N PF04801.8 ETO01274.1 - 0.12 11.2 0.1 0.13 11.1 0.0 1.0 1 0 0 1 1 1 0 Sin-like protein conserved region DUF2258 PF10015.4 ETO01274.1 - 1.2 9.0 5.2 0.71 9.7 1.2 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2258) WD40 PF00400.27 ETO01275.1 - 1.5e-30 103.9 15.4 1.3e-12 47.0 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO01275.1 - 2.3e-08 32.6 4.4 0.00016 19.9 0.2 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 HAD PF12710.2 ETO01275.1 - 0.023 14.8 0.1 0.59 10.2 0.1 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase NTNH_C PF08470.5 ETO01275.1 - 0.068 12.8 1.2 13 5.3 0.0 2.6 1 1 2 3 3 3 0 Nontoxic nonhaemagglutinin C-terminal DUF2559 PF10832.3 ETO01275.1 - 0.14 11.9 1.3 19 5.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2559) NACHT PF05729.7 ETO01276.1 - 0.006 16.2 0.0 0.0064 16.1 0.0 1.1 1 0 0 1 1 1 1 NACHT domain CRISPR_Cse1 PF09481.5 ETO01278.1 - 0.14 10.8 0.1 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) Daxx PF03344.10 ETO01280.1 - 1.8 6.9 48.8 0.05 12.0 7.5 3.5 3 0 0 3 3 3 0 Daxx Family Myc_N PF01056.13 ETO01280.1 - 2.6 7.1 32.7 0.07 12.2 5.5 3.4 3 0 0 3 3 3 0 Myc amino-terminal region Nucleoplasmin PF03066.10 ETO01280.1 - 6.8 6.1 34.3 0.12 11.8 4.3 3.1 3 0 0 3 3 3 0 Nucleoplasmin CobT PF06213.7 ETO01280.1 - 8 5.4 50.9 2.4 7.1 11.4 3.4 3 0 0 3 3 3 0 Cobalamin biosynthesis protein CobT DUF4065 PF13274.1 ETO01283.1 - 0.031 14.9 1.0 0.031 14.9 0.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4065) PI3_PI4_kinase PF00454.22 ETO01285.1 - 6.2e-37 127.3 0.2 1.6e-36 125.9 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 ETO01285.1 - 0.002 18.1 3.8 0.24 11.4 0.1 3.8 3 0 0 3 3 3 2 Rapamycin binding domain FATC PF02260.15 ETO01286.1 - 1.2e-09 37.4 0.1 2.6e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 FATC domain Nucleoplasmin PF03066.10 ETO01286.1 - 0.12 11.8 3.4 0.21 11.0 2.3 1.4 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 ETO01286.1 - 0.73 9.4 7.0 0.25 10.9 2.6 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region PBP1_TM PF14812.1 ETO01286.1 - 2.7 8.3 8.2 5.7 7.3 5.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF258 PF03193.11 ETO01287.1 - 0.065 12.4 0.0 0.17 11.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DnaJ PF00226.26 ETO01288.1 - 2.5e-20 71.9 1.2 4.6e-20 71.1 0.9 1.5 1 0 0 1 1 1 1 DnaJ domain RNA_pol_Rpb1_5 PF04998.12 ETO01288.1 - 0.0091 15.2 1.0 0.029 13.6 0.5 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 Ctr PF04145.10 ETO01288.1 - 0.093 12.7 2.3 0.15 12.1 0.0 2.2 2 1 0 2 2 2 0 Ctr copper transporter family T4_deiodinase PF00837.12 ETO01289.1 - 4.1e-17 61.9 0.0 7.6e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 Iodothyronine deiodinase AhpC-TSA PF00578.16 ETO01289.1 - 0.094 12.3 0.2 0.32 10.6 0.1 1.9 1 1 0 1 1 1 0 AhpC/TSA family ADK_lid PF05191.9 ETO01289.1 - 0.1 12.2 0.1 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 Adenylate kinase, active site lid WD40 PF00400.27 ETO01290.1 - 9e-07 28.5 0.2 0.00065 19.4 0.2 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat Tautomerase_2 PF14552.1 ETO01290.1 - 0.024 14.6 0.3 0.044 13.8 0.2 1.4 1 0 0 1 1 1 0 Tautomerase enzyme CopD PF05425.8 ETO01291.1 - 6.4 7.0 8.7 0.53 10.5 1.4 2.3 2 0 0 2 2 2 0 Copper resistance protein D HEAT_2 PF13646.1 ETO01292.1 - 4.6e-05 23.6 0.0 0.014 15.6 0.0 2.4 2 0 0 2 2 2 2 HEAT repeats Xpo1 PF08389.7 ETO01292.1 - 0.00011 22.0 0.6 4 7.3 0.0 3.5 3 0 0 3 3 3 2 Exportin 1-like protein Mo25 PF08569.6 ETO01292.1 - 0.0039 16.2 0.5 0.0084 15.1 0.1 1.7 1 1 1 2 2 2 1 Mo25-like PBS_linker_poly PF00427.16 ETO01292.1 - 0.023 14.3 0.1 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide HEAT PF02985.17 ETO01292.1 - 0.044 13.8 0.5 9.8 6.5 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.1 ETO01292.1 - 0.054 14.0 0.0 2 8.9 0.0 3.2 3 0 0 3 3 3 0 HEAT-like repeat DUF3944 PF13099.1 ETO01292.1 - 0.25 10.8 5.2 0.47 9.9 0.4 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF3944) WD40 PF00400.27 ETO01293.1 - 3.7e-22 77.3 0.6 4e-11 42.3 0.1 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF3732 PF12532.3 ETO01293.1 - 0.0066 16.0 2.1 0.05 13.1 0.1 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF3732) RVT_1 PF00078.22 ETO01297.1 - 2.9e-35 121.5 0.3 6.5e-35 120.4 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Viral_Beta_CD PF04530.7 ETO01298.1 - 0.3 11.2 0.1 0.3 11.2 0.1 1.8 2 0 0 2 2 2 0 Viral Beta C/D like family Ctf8 PF09696.5 ETO01299.1 - 0.41 10.4 5.3 0.53 10.0 3.2 1.5 1 1 0 1 1 1 0 Ctf8 FANCI_S4 PF14678.1 ETO01301.1 - 0.014 14.5 0.1 0.016 14.3 0.1 1.1 1 0 0 1 1 1 0 FANCI solenoid 4 Methyltransf_12 PF08242.7 ETO01301.1 - 0.068 13.6 0.4 0.075 13.5 0.3 1.3 1 0 0 1 1 1 0 Methyltransferase domain Menin PF05053.8 ETO01301.1 - 9.2 4.2 7.4 11 4.0 5.1 1.0 1 0 0 1 1 1 0 Menin Pro-rich PF15240.1 ETO01302.1 - 0.12 12.4 0.4 0.16 12.0 0.3 1.1 1 0 0 1 1 1 0 Proline-rich DUF1199 PF06712.6 ETO01302.1 - 3.3 7.6 5.6 2.8 7.8 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1199) CAP_GLY PF01302.20 ETO01303.1 - 0.044 13.4 1.4 4.1 7.1 0.2 2.4 2 1 0 2 2 2 0 CAP-Gly domain DUF4302 PF14135.1 ETO01304.1 - 0.022 14.1 3.8 0.028 13.8 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4302) DUF4662 PF15578.1 ETO01306.1 - 0.0054 16.3 3.2 0.0054 16.3 2.2 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4662) Med19 PF10278.4 ETO01306.1 - 0.011 15.4 12.5 0.011 15.4 8.6 4.7 5 0 0 5 5 5 0 Mediator of RNA pol II transcription subunit 19 TEX19 PF15553.1 ETO01306.1 - 7.6 6.3 10.5 0.26 11.1 2.9 1.8 2 0 0 2 2 2 0 Testis-expressed protein 19 Skp1_POZ PF03931.10 ETO01307.1 - 0.057 13.5 0.1 0.085 12.9 0.1 1.2 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain Ufm1 PF03671.9 ETO01308.1 - 0.014 15.0 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin fold modifier 1 protein HEAT_2 PF13646.1 ETO01309.1 - 8.6e-12 45.1 0.1 8.3e-05 22.8 0.0 4.0 2 1 2 4 4 4 3 HEAT repeats DUF2435 PF10363.4 ETO01309.1 - 0.00029 20.6 4.2 0.0023 17.7 0.1 3.6 2 1 2 4 4 4 2 Protein of unknown function (DUF2435) DUF4093 PF13331.1 ETO01311.1 - 0.011 15.8 0.4 0.04 14.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4093) WD40 PF00400.27 ETO01313.1 - 7.7e-45 149.2 16.5 1.3e-12 47.0 0.3 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO01313.1 - 8.1e-11 40.7 1.0 0.038 12.1 0.0 4.0 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO01313.1 - 0.0051 15.6 2.2 1.2 7.8 0.1 3.8 1 1 3 4 4 4 2 Nup133 N terminal like Ion_trans PF00520.26 ETO01315.1 - 5.1e-06 25.8 4.3 1.1e-05 24.8 1.8 1.9 2 0 0 2 2 2 1 Ion transport protein WD40 PF00400.27 ETO01316.1 - 2.7e-54 179.2 18.7 1.1e-10 40.9 0.0 7.1 6 2 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO01316.1 - 1.9e-09 36.2 3.3 0.051 11.7 0.0 4.8 2 1 3 5 5 5 5 Nucleoporin Nup120/160 Kelch_1 PF01344.20 ETO01317.1 - 1.9e-08 33.7 2.1 0.00019 20.8 0.3 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO01317.1 - 2.5e-05 24.2 3.1 3 8.1 0.2 4.6 3 1 1 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO01317.1 - 0.00022 20.8 0.4 0.019 14.7 0.0 3.2 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO01317.1 - 0.00037 20.3 1.6 4.8 7.2 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO01317.1 - 0.0084 15.8 2.2 2.8 7.8 0.1 3.7 4 0 0 4 4 4 2 Kelch motif MHC_II_beta PF00969.14 ETO01318.1 - 0.077 12.9 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Class II histocompatibility antigen, beta domain Peptidase_M22 PF00814.20 ETO01319.1 - 0.082 12.3 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Glycoprotease family Actin PF00022.14 ETO01320.1 - 9.7e-27 93.3 0.0 1.1e-26 93.2 0.0 1.0 1 0 0 1 1 1 1 Actin HN PF00423.14 ETO01320.1 - 0.049 11.9 0.0 0.062 11.5 0.0 1.1 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase Troponin PF00992.15 ETO01321.1 - 0.07 13.1 8.8 0.1 12.6 6.1 1.3 1 0 0 1 1 1 0 Troponin LRS4 PF10422.4 ETO01321.1 - 0.097 12.0 11.2 0.11 11.7 7.7 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 CDC37_N PF03234.9 ETO01321.1 - 0.13 12.6 10.2 0.15 12.3 7.1 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding WEMBL PF05701.6 ETO01321.1 - 0.21 10.0 11.0 0.24 9.8 7.6 1.0 1 0 0 1 1 1 0 Weak chloroplast movement under blue light EF1_GNE PF00736.14 ETO01321.1 - 0.23 11.2 3.3 0.29 10.8 2.3 1.3 1 0 0 1 1 1 0 EF-1 guanine nucleotide exchange domain Uds1 PF15456.1 ETO01321.1 - 0.23 11.4 7.5 0.22 11.5 3.8 1.7 1 1 1 2 2 2 0 Up-regulated During Septation IncA PF04156.9 ETO01321.1 - 0.74 9.3 16.1 0.93 9.0 11.1 1.0 1 0 0 1 1 1 0 IncA protein DDHD PF02862.12 ETO01321.1 - 1.3 8.7 7.6 1.4 8.6 5.2 1.0 1 0 0 1 1 1 0 DDHD domain SieB PF14163.1 ETO01321.1 - 1.3 8.5 6.7 0.093 12.3 0.5 2.0 1 1 0 2 2 2 0 Superinfection exclusion protein B Fib_alpha PF08702.5 ETO01321.1 - 1.5 8.9 14.0 2.6 8.1 9.7 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family YjgP_YjgQ PF03739.9 ETO01321.1 - 1.6 7.3 6.9 1.8 7.2 4.8 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF972 PF06156.8 ETO01321.1 - 2 8.7 12.7 3.3 8.1 8.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF4337 PF14235.1 ETO01321.1 - 2 8.2 6.7 2.5 7.9 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF1068 PF06364.7 ETO01321.1 - 2.9 7.4 5.7 3.3 7.2 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) Mit_ribos_Mrp51 PF11709.3 ETO01321.1 - 5.4 6.1 9.7 6.1 5.9 6.8 1.0 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit GAGA_bind PF06217.7 ETO01321.1 - 9.6 6.0 9.9 10 5.9 6.9 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Imm7 PF15588.1 ETO01322.1 - 0.0077 16.2 0.5 0.0091 16.0 0.3 1.1 1 0 0 1 1 1 1 Immunity protein 7 HOOK PF05622.7 ETO01322.1 - 0.026 12.3 4.3 0.031 12.1 3.0 1.0 1 0 0 1 1 1 0 HOOK protein DUF4252 PF14060.1 ETO01322.1 - 0.032 13.7 2.5 0.038 13.5 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) CDC37_N PF03234.9 ETO01322.1 - 0.037 14.3 4.8 0.046 14.0 3.4 1.0 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Bap31 PF05529.7 ETO01322.1 - 0.073 12.5 2.3 0.08 12.3 1.6 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF603 PF04645.7 ETO01322.1 - 0.093 12.6 2.4 0.11 12.4 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF603 CASP_C PF08172.7 ETO01322.1 - 0.17 10.8 3.5 0.22 10.5 2.3 1.3 1 1 0 1 1 1 0 CASP C terminal TTKRSYEDQ PF10212.4 ETO01322.1 - 0.18 10.7 4.0 0.2 10.5 2.8 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Rabaptin PF03528.10 ETO01322.1 - 0.2 11.5 4.3 0.25 11.2 3.0 1.1 1 0 0 1 1 1 0 Rabaptin SseC PF04888.7 ETO01322.1 - 0.3 10.3 4.4 0.37 10.0 3.0 1.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family TPD52 PF04201.10 ETO01322.1 - 0.54 9.9 6.6 0.95 9.1 3.5 1.8 1 1 1 2 2 2 0 Tumour protein D52 family PUB PF09409.5 ETO01323.1 - 0.00019 21.1 1.9 0.0004 20.0 0.1 2.3 2 1 0 2 2 2 1 PUB domain DUF524 PF04411.7 ETO01323.1 - 0.057 13.2 0.1 0.1 12.4 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF524) EST1_DNA_bind PF10373.4 ETO01324.1 - 0.18 11.0 7.4 0.24 10.5 4.3 1.8 1 1 0 1 1 1 0 Est1 DNA/RNA binding domain RNA_pol_Rpb4 PF03874.11 ETO01325.1 - 0.019 14.9 1.0 0.02 14.8 0.7 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb4 FrhB_FdhB_C PF04432.8 ETO01325.1 - 0.019 14.3 0.2 0.022 14.1 0.1 1.0 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus Ribosomal_S6 PF01250.12 ETO01325.1 - 0.043 13.6 0.2 0.32 10.8 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein S6 EcsC PF12787.2 ETO01325.1 - 0.052 12.9 0.4 0.055 12.8 0.3 1.0 1 0 0 1 1 1 0 EcsC protein family ImcF-related_N PF14331.1 ETO01325.1 - 0.14 11.0 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 ImcF-related N-terminal domain DUF327 PF03885.8 ETO01327.1 - 0.026 14.3 0.5 0.034 13.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF327) Toxin_44 PF15523.1 ETO01327.1 - 0.099 12.5 1.9 0.16 11.8 0.7 1.7 2 0 0 2 2 2 0 Putative toxin 44 DUF617 PF04759.8 ETO01329.1 - 0.026 14.1 0.3 0.033 13.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF617 SseB_C PF14581.1 ETO01329.1 - 0.059 13.2 0.5 0.46 10.3 0.3 2.0 1 1 1 2 2 2 0 SseB protein C-terminal domain PV-1 PF06637.6 ETO01329.1 - 0.1 11.1 2.3 0.11 11.1 1.6 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) zf-RING_UBOX PF13445.1 ETO01330.1 - 0.035 13.8 2.3 0.096 12.4 1.0 2.1 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 ETO01330.1 - 6.5 6.8 23.5 0.078 13.0 7.5 3.5 2 2 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) TRAP_alpha PF03896.11 ETO01331.1 - 0.05 12.6 2.0 0.054 12.4 1.4 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nucleoplasmin PF03066.10 ETO01331.1 - 0.38 10.2 4.0 0.38 10.2 2.8 1.1 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 ETO01331.1 - 4.9 7.4 8.4 6.8 6.9 5.8 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain UPF0300 PF08594.5 ETO01332.1 - 0.092 11.6 2.8 0.067 12.1 0.7 1.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0300) ART PF01129.13 ETO01333.1 - 5.7e-06 25.5 1.9 6.6e-06 25.3 0.2 1.9 3 0 0 3 3 3 1 NAD:arginine ADP-ribosyltransferase PUB PF09409.5 ETO01333.1 - 0.00042 20.0 0.2 0.002 17.8 0.1 2.3 1 0 0 1 1 1 1 PUB domain WD40 PF00400.27 ETO01334.1 - 1.7e-06 27.6 4.3 0.25 11.2 0.5 4.3 3 1 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO01334.1 - 0.0062 14.7 0.0 0.012 13.7 0.0 1.5 1 1 0 1 1 1 1 Nucleoporin Nup120/160 DUF3043 PF11241.3 ETO01334.1 - 0.022 14.3 0.1 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DUF4118 PF13493.1 ETO01334.1 - 0.12 12.5 1.7 0.25 11.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4118) Kelch_6 PF13964.1 ETO01335.1 - 0.16 12.2 0.5 1.4 9.2 0.1 2.4 2 0 0 2 2 2 0 Kelch motif Ral PF11058.3 ETO01336.1 - 0.092 12.1 0.9 8.2 5.8 0.0 3.1 3 0 0 3 3 3 0 Antirestriction protein Ral Ammonium_transp PF00909.16 ETO01337.1 - 0.046 12.1 0.1 0.059 11.8 0.1 1.1 1 0 0 1 1 1 0 Ammonium Transporter Family DUF1371 PF07115.6 ETO01337.1 - 1 9.5 8.8 0.25 11.5 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1371) DUF2163 PF09931.4 ETO01338.1 - 0.037 13.8 0.0 0.049 13.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2163) Glyco_transf_8 PF01501.15 ETO01338.1 - 0.043 13.1 0.5 0.051 12.9 0.4 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 8 FPL PF09758.4 ETO01339.1 - 1.5e-05 24.7 2.4 0.0064 16.2 0.1 2.3 1 1 1 2 2 2 2 Uncharacterised conserved protein RNA_binding PF01877.12 ETO01339.1 - 0.036 14.0 0.3 0.18 11.7 0.2 1.9 1 1 0 1 1 1 0 RNA binding UPF0223 PF05256.7 ETO01339.1 - 0.044 13.8 1.2 7.8 6.6 0.1 2.6 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0223) Imm16 PF15565.1 ETO01339.1 - 0.089 12.6 1.2 2.6 7.9 0.2 2.5 1 1 2 3 3 3 0 Immunity protein 16 PAM2 PF07145.10 ETO01340.1 - 0.00095 18.5 3.7 0.002 17.5 2.6 1.5 1 0 0 1 1 1 1 Ataxin-2 C-terminal region VWA_2 PF13519.1 ETO01342.1 - 7.4e-10 39.1 0.0 1.6e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain SecA_DEAD PF07517.9 ETO01342.1 - 0.027 13.7 3.5 0.043 13.1 0.0 2.9 4 0 0 4 4 4 0 SecA DEAD-like domain DUF258 PF03193.11 ETO01343.1 - 7.1e-06 25.3 0.3 4.5e-05 22.7 0.2 2.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 ETO01343.1 - 9.9e-05 22.2 0.0 9.9e-05 22.2 0.0 3.4 4 0 0 4 4 4 1 50S ribosome-binding GTPase ABC_tran PF00005.22 ETO01343.1 - 0.006 16.8 0.1 0.006 16.8 0.1 4.4 5 1 0 5 5 5 1 ABC transporter AAA_29 PF13555.1 ETO01343.1 - 0.012 15.1 0.1 0.025 14.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 ETO01343.1 - 0.014 15.8 3.2 0.048 14.1 0.0 3.6 3 0 0 3 3 3 0 Miro-like protein AAA_16 PF13191.1 ETO01343.1 - 0.036 14.0 0.0 0.24 11.3 0.0 2.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 ETO01343.1 - 0.094 12.1 1.4 0.51 9.6 0.1 2.9 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 ETO01343.1 - 0.35 10.6 0.6 0.78 9.5 0.4 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 ETO01343.1 - 1.5 8.9 7.4 0.28 11.3 0.1 3.7 5 0 0 5 5 5 0 AAA domain Aldo_ket_red PF00248.16 ETO01344.1 - 7e-05 21.7 0.0 8.5e-05 21.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ADIP PF11559.3 ETO01345.1 - 6.6e-07 29.3 10.6 3.5e-05 23.7 2.6 2.2 2 0 0 2 2 2 2 Afadin- and alpha -actinin-Binding DUF3520 PF12034.3 ETO01345.1 - 0.0043 17.1 3.7 0.006 16.7 2.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3520) HALZ PF02183.13 ETO01345.1 - 0.0074 15.9 4.5 0.047 13.3 3.1 2.3 1 1 0 1 1 1 1 Homeobox associated leucine zipper DUF904 PF06005.7 ETO01345.1 - 0.008 16.4 8.6 0.008 16.4 5.9 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF904) IncA PF04156.9 ETO01345.1 - 0.0086 15.6 7.0 0.0086 15.6 4.8 1.6 1 1 1 2 2 2 1 IncA protein DUF3606 PF12244.3 ETO01345.1 - 0.028 14.0 0.0 0.065 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) DUF2857 PF11198.3 ETO01345.1 - 0.032 13.7 1.0 3 7.3 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2857) DUF1664 PF07889.7 ETO01345.1 - 0.073 12.8 2.7 0.081 12.7 1.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Shugoshin_N PF07558.6 ETO01345.1 - 0.11 12.2 6.2 1.6 8.5 0.5 2.7 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region ApoO PF09769.4 ETO01345.1 - 0.13 11.9 4.1 0.33 10.6 2.9 1.8 1 1 0 1 1 1 0 Apolipoprotein O FlaC_arch PF05377.6 ETO01345.1 - 0.13 12.2 4.5 1.9 8.4 0.2 3.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF4201 PF13870.1 ETO01345.1 - 0.15 11.4 11.4 0.016 14.6 4.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) APG6 PF04111.7 ETO01345.1 - 0.34 9.8 10.8 0.47 9.4 7.3 1.3 1 1 0 1 1 1 0 Autophagy protein Apg6 RyR PF02026.11 ETO01345.1 - 0.55 10.3 3.9 0.14 12.1 0.5 2.1 2 1 0 2 2 2 0 RyR domain Mod_r PF07200.8 ETO01345.1 - 0.58 10.0 12.6 0.087 12.7 4.4 2.4 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Reo_sigmaC PF04582.7 ETO01345.1 - 0.61 9.2 6.5 0.74 8.9 4.5 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Med9 PF07544.8 ETO01345.1 - 0.82 9.4 6.3 0.38 10.5 1.3 2.7 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Cortex-I_coil PF09304.5 ETO01345.1 - 0.98 9.4 12.1 0.35 10.9 5.1 2.2 1 1 1 2 2 2 0 Cortexillin I, coiled coil Syntaxin-6_N PF09177.6 ETO01345.1 - 2.2 8.7 9.0 3.2 8.2 3.6 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal V_ATPase_I PF01496.14 ETO01345.1 - 3.8 5.2 7.9 3.9 5.1 5.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.4 ETO01345.1 - 6.6 6.5 19.6 39 4.0 13.6 2.0 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LMBR1 PF04791.11 ETO01345.1 - 9.7 4.6 7.7 11 4.4 5.1 1.2 1 1 0 1 1 1 0 LMBR1-like membrane protein Pox_E10 PF04805.7 ETO01347.1 - 0.0045 16.4 0.6 0.11 12.0 0.0 2.7 2 0 0 2 2 2 1 E10-like protein conserved region AAA_22 PF13401.1 ETO01347.1 - 0.057 13.5 0.0 0.23 11.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain PAS_8 PF13188.1 ETO01348.1 - 0.13 12.2 0.0 0.45 10.4 0.0 1.9 1 1 0 1 1 1 0 PAS domain PBP1_TM PF14812.1 ETO01349.1 - 0.016 15.4 2.0 0.016 15.4 1.4 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF912 PF06024.7 ETO01349.1 - 0.29 11.1 2.3 0.99 9.4 0.4 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4611 PF15387.1 ETO01349.1 - 0.86 9.7 11.6 1.4 9.1 5.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Abi_2 PF07751.6 ETO01349.1 - 8.9 6.4 12.7 0.88 9.7 5.3 1.8 2 0 0 2 2 2 0 Abi-like protein Flavodoxin_1 PF00258.20 ETO01351.1 - 7.2e-37 126.5 2.5 7.2e-37 126.5 1.7 2.2 2 0 0 2 2 2 1 Flavodoxin FAD_binding_1 PF00667.15 ETO01351.1 - 1.3e-28 99.9 0.1 5.4e-28 97.9 0.0 1.9 1 1 1 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.16 ETO01351.1 - 1.4e-17 64.2 0.0 9e-17 61.6 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF1510 PF07423.6 ETO01351.1 - 0.0028 17.0 1.1 0.062 12.6 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1510) NAD_binding_6 PF08030.7 ETO01351.1 - 0.033 14.0 0.4 2.7 7.8 0.0 2.9 3 0 0 3 3 3 0 Ferric reductase NAD binding domain NACHT PF05729.7 ETO01353.1 - 0.00045 19.9 0.1 0.00068 19.3 0.1 1.3 1 0 0 1 1 1 1 NACHT domain DUF2160 PF09928.4 ETO01355.1 - 0.068 13.2 0.6 0.23 11.5 0.0 2.0 1 1 0 2 2 2 0 Predicted small integral membrane protein (DUF2160) DUF2556 PF10831.3 ETO01355.1 - 0.11 12.1 2.9 0.28 10.8 2.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2556) WD40 PF00400.27 ETO01356.1 - 0.041 13.7 0.0 1.8 8.5 0.0 2.3 1 1 1 2 2 2 0 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO01357.1 - 0.015 15.4 0.2 0.052 13.7 0.0 2.0 2 1 0 2 2 2 0 Kelch motif WD40 PF00400.27 ETO01358.1 - 1.7e-79 259.0 25.9 2.2e-11 43.1 0.0 7.1 6 1 1 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO01358.1 - 4e-13 49.4 0.2 0.00028 20.6 0.0 3.6 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.4 ETO01358.1 - 0.0036 16.7 0.2 0.32 10.3 0.2 2.5 1 1 1 2 2 2 1 Lipoprotein LpqB beta-propeller domain Cytochrom_D1 PF02239.11 ETO01358.1 - 0.0044 15.3 1.4 0.91 7.7 0.0 3.1 1 1 2 3 3 3 2 Cytochrome D1 heme domain Arena_nucleocap PF00843.12 ETO01358.1 - 0.014 13.3 0.9 3.7 5.3 0.0 2.9 2 1 1 3 3 3 0 Arenavirus nucleocapsid protein DUF4221 PF13970.1 ETO01358.1 - 0.034 13.4 0.3 13 4.9 0.0 3.0 2 1 2 4 4 4 0 Domain of unknown function (DUF4221) NYD-SP28_assoc PF14775.1 ETO01358.1 - 0.08 12.6 0.3 8.4 6.1 0.0 3.6 4 0 0 4 4 4 0 Sperm tail C-terminal domain Resistin PF06954.6 ETO01358.1 - 0.17 12.1 0.4 50 4.2 0.0 3.5 1 1 3 4 4 4 0 Resistin PD40 PF07676.7 ETO01358.1 - 3.2 7.5 18.9 4.9 6.9 0.1 5.8 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 ETO01358.1 - 7.6 5.9 16.6 7.5 5.9 0.0 5.0 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature Phycobilisome PF00502.14 ETO01359.1 - 0.037 13.7 0.0 0.045 13.4 0.0 1.5 1 1 0 1 1 1 0 Phycobilisome protein DMPK_coil PF08826.5 ETO01361.1 - 0.022 14.6 0.6 0.041 13.7 0.4 1.4 1 0 0 1 1 1 0 DMPK coiled coil domain like BNIP2 PF12496.3 ETO01361.1 - 0.039 14.1 0.3 0.043 13.9 0.2 1.1 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DUF342 PF03961.8 ETO01361.1 - 0.044 12.2 6.1 0.053 11.9 4.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Secretin PF00263.16 ETO01361.1 - 0.13 11.5 2.3 0.18 11.2 1.6 1.1 1 0 0 1 1 1 0 Bacterial type II and III secretion system protein DivIC PF04977.10 ETO01361.1 - 3.1 7.3 5.8 1 8.9 1.7 1.8 1 1 1 2 2 2 0 Septum formation initiator YqzH PF14164.1 ETO01362.1 - 0.15 12.0 8.7 1.7 8.6 1.0 4.1 3 0 0 3 3 3 0 YqzH-like protein UCH PF00443.24 ETO01364.1 - 2.7e-09 36.5 0.6 6.4e-09 35.3 0.5 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 ETO01365.1 - 4.6e-53 175.3 16.4 2.6e-13 49.2 0.1 4.7 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 ETO01365.1 - 1.1e-07 31.7 0.3 4e-06 26.6 0.0 2.4 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO01365.1 - 1.5e-07 30.0 2.0 0.67 8.0 0.0 4.1 1 1 2 4 4 4 4 Nucleoporin Nup120/160 PD40 PF07676.7 ETO01365.1 - 0.0001 21.8 5.5 3.3 7.4 0.0 4.4 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat Pentapeptide_4 PF13599.1 ETO01365.1 - 0.00032 20.4 0.9 0.00063 19.5 0.6 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 ETO01365.1 - 0.0028 17.4 2.7 0.0066 16.3 1.9 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETO01365.1 - 0.0041 16.3 1.5 0.069 12.4 0.6 2.2 1 1 0 1 1 1 1 Pentapeptide repeats (8 copies) Cytochrom_D1 PF02239.11 ETO01365.1 - 0.013 13.8 0.2 0.023 13.0 0.1 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain DUF3732 PF12532.3 ETO01365.1 - 0.14 11.6 1.2 21 4.5 0.0 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF3732) Ndc1_Nup PF09531.5 ETO01366.1 - 1.2 7.4 6.7 1.2 7.4 4.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1183 PF06682.7 ETO01366.1 - 7.5 6.0 11.2 0.13 11.7 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1183) EssA PF10661.4 ETO01367.1 - 0.24 11.0 5.5 0.35 10.5 3.8 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA MecA PF05389.7 ETO01367.1 - 3.1 7.2 6.8 63 3.0 4.7 2.0 1 1 0 1 1 1 0 Negative regulator of genetic competence (MecA) Reticulon PF02453.12 ETO01368.1 - 0.037 13.6 2.6 0.063 12.8 1.8 1.3 1 0 0 1 1 1 0 Reticulon DUF996 PF06195.8 ETO01368.1 - 0.085 12.8 1.8 0.12 12.4 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF996) DUF2254 PF10011.4 ETO01368.1 - 0.47 8.8 3.2 0.21 10.0 0.1 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) FRG2 PF15315.1 ETO01369.1 - 0.094 12.6 0.8 0.12 12.3 0.5 1.1 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Pex14_N PF04695.8 ETO01369.1 - 0.14 12.1 2.8 0.15 12.1 1.9 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4058 PF13267.1 ETO01369.1 - 0.19 10.8 3.6 0.23 10.5 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4058) PGM_PMM_I PF02878.11 ETO01370.1 - 7.6e-15 54.6 0.1 1.1e-07 31.4 0.0 3.1 1 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 ETO01370.1 - 2.1e-09 37.6 0.0 4.6e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DUF4355 PF14265.1 ETO01371.1 - 7.8 6.4 28.0 9.1 6.2 19.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) BRF1 PF07741.8 ETO01371.1 - 7.8 6.7 23.1 9.8 6.4 16.0 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Roughex PF06020.6 ETO01372.1 - 0.24 10.0 4.3 0.38 9.3 3.0 1.2 1 0 0 1 1 1 0 Drosophila roughex protein CDC45 PF02724.9 ETO01372.1 - 0.28 9.1 8.5 0.44 8.5 5.9 1.2 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.27 ETO01373.1 - 6.1e-09 35.4 2.4 4.1e-08 32.8 0.1 2.4 2 1 0 2 2 2 1 WD domain, G-beta repeat WD40 PF00400.27 ETO01374.1 - 2.4e-25 87.4 6.4 5.8e-11 41.8 0.6 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO01374.1 - 0.0078 14.4 0.0 1.2 7.2 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 AstE_AspA PF04952.9 ETO01375.1 - 2.3e-18 66.1 0.0 2.5e-18 65.9 0.0 1.0 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family zf-CCHC PF00098.18 ETO01376.1 - 0.003 17.4 1.4 0.003 17.4 0.9 2.3 2 0 0 2 2 2 1 Zinc knuckle Ribophorin_II PF05817.9 ETO01376.1 - 0.15 10.2 5.7 0.87 7.7 0.3 2.2 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit Ribophorin II cwf18 PF08315.7 ETO01376.1 - 0.19 12.2 5.2 0.42 11.0 3.6 1.5 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor SPARC_Ca_bdg PF10591.4 ETO01377.1 - 0.01 15.8 1.8 0.014 15.4 1.3 1.2 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Enkurin PF13864.1 ETO01377.1 - 0.046 13.9 5.3 0.055 13.6 3.7 1.1 1 0 0 1 1 1 0 Calmodulin-binding COG2 PF06148.6 ETO01377.1 - 0.063 13.1 1.4 0.081 12.7 1.0 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Myb_DNA-bind_3 PF12776.2 ETO01377.1 - 0.085 13.4 2.2 0.11 13.1 1.5 1.2 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain ADSL_C PF10397.4 ETO01377.1 - 0.13 12.2 0.2 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminus S_100 PF01023.14 ETO01377.1 - 0.19 11.0 4.8 1.2 8.5 0.4 2.4 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain GatB_Yqey PF02637.13 ETO01377.1 - 0.37 10.5 6.8 0.041 13.5 1.8 1.5 2 0 0 2 2 2 0 GatB domain TPR_8 PF13181.1 ETO01377.1 - 0.49 10.2 9.4 2.7 7.9 0.2 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat ABC2_membrane_3 PF12698.2 ETO01377.1 - 1.1 8.1 4.2 1.1 8.2 2.9 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Sbi-IV PF11621.3 ETO01377.1 - 1.7 8.8 4.8 1.1 9.4 1.4 1.9 1 1 1 2 2 2 0 C3 binding domain 4 of IgG-bind protein SBI DUF809 PF05663.6 ETO01378.1 - 0.22 11.4 6.5 0.3 10.9 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF809) DUF342 PF03961.8 ETO01378.1 - 0.48 8.7 10.4 0.55 8.5 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FlaC_arch PF05377.6 ETO01378.1 - 1.6 8.6 11.2 1.6 8.6 0.8 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) IFP_35_N PF07334.8 ETO01378.1 - 5 7.1 12.2 1.8 8.5 3.3 2.9 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DHHW PF14286.1 ETO01379.1 - 1.4 8.1 10.4 1.5 8.0 7.2 1.0 1 0 0 1 1 1 0 DHHW protein DUF1510 PF07423.6 ETO01379.1 - 1.5 8.0 22.7 1.9 7.8 15.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SpoIIIAH PF12685.2 ETO01379.1 - 3.1 7.2 12.5 3.6 7.0 8.7 1.0 1 0 0 1 1 1 0 SpoIIIAH-like protein MSA_2 PF00985.12 ETO01379.1 - 3.2 7.8 12.8 4 7.5 8.9 1.1 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family Gag_spuma PF03276.9 ETO01379.1 - 4.2 5.5 9.1 4.5 5.4 6.3 1.0 1 0 0 1 1 1 0 Spumavirus gag protein SRP-alpha_N PF04086.8 ETO01379.1 - 4.5 6.5 20.9 5.4 6.3 14.5 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MIP-T3 PF10243.4 ETO01379.1 - 5.4 5.3 27.2 6.3 5.1 18.9 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 FLO_LFY PF01698.11 ETO01379.1 - 5.5 5.7 14.7 6.5 5.4 10.2 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF4551 PF15087.1 ETO01379.1 - 6.3 5.0 9.3 7.1 4.8 6.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF3827 PF12877.2 ETO01379.1 - 6.4 4.7 10.4 6.8 4.6 7.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) RNA_polI_A34 PF08208.6 ETO01379.1 - 7 6.2 31.1 9 5.9 21.5 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RR_TM4-6 PF06459.7 ETO01379.1 - 8.6 6.1 17.3 11 5.8 12.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BSMAP PF12280.3 ETO01379.1 - 8.8 6.1 8.7 11 5.7 6.0 1.3 1 0 0 1 1 1 0 Brain specific membrane anchored protein MFMR PF07777.6 ETO01379.1 - 9.7 6.0 11.1 12 5.7 7.7 1.2 1 0 0 1 1 1 0 G-box binding protein MFMR MAP7 PF05672.6 ETO01381.1 - 2.7 7.3 16.7 2.8 7.3 11.5 1.0 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Tfb4 PF03850.9 ETO01383.1 - 0.00068 18.9 5.2 0.00086 18.6 3.6 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 Vfa1 PF08432.5 ETO01383.1 - 0.012 15.6 7.6 0.012 15.6 5.3 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 AAA_5 PF07728.9 ETO01383.1 - 0.088 12.5 0.3 0.13 11.9 0.2 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RloB PF13707.1 ETO01383.1 - 0.21 11.1 13.5 0.31 10.6 9.3 1.2 1 0 0 1 1 1 0 RloB-like protein Complex1_51K PF01512.12 ETO01383.1 - 0.24 11.1 7.5 6.8 6.4 5.2 2.0 1 1 0 1 1 1 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit Laps PF10169.4 ETO01383.1 - 2 8.6 21.4 0.7 10.1 9.1 2.1 2 0 0 2 2 2 0 Learning-associated protein DUF724 PF05266.9 ETO01383.1 - 2.3 7.7 22.5 0.26 10.8 8.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) TPD52 PF04201.10 ETO01383.1 - 2.3 7.9 14.4 2.1 8.0 3.9 2.2 2 0 0 2 2 2 0 Tumour protein D52 family DUF641 PF04859.7 ETO01383.1 - 3.2 7.5 18.0 5.2 6.8 5.1 2.4 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) TMF_DNA_bd PF12329.3 ETO01383.1 - 6.6 6.6 28.8 3.7 7.4 11.0 2.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF2500 PF10694.4 ETO01383.1 - 7.1 6.6 12.0 2.7 8.0 5.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2500) PBP_dimer PF03717.10 ETO01384.1 - 0.18 11.8 3.6 0.43 10.6 0.8 2.2 2 1 1 3 3 3 0 Penicillin-binding Protein dimerisation domain HEAT_2 PF13646.1 ETO01385.1 - 1.7e-09 37.7 0.0 4.3e-07 30.1 0.0 2.1 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 ETO01385.1 - 1.1e-07 31.3 0.0 0.00061 19.6 0.0 3.4 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 ETO01385.1 - 0.0015 18.9 0.0 0.027 14.9 0.0 2.6 2 1 1 3 3 3 1 HEAT-like repeat DUF3137 PF11335.3 ETO01385.1 - 0.0025 17.4 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3137) CLASP_N PF12348.3 ETO01385.1 - 0.0082 15.5 0.7 0.068 12.5 0.0 2.1 1 1 1 2 2 2 1 CLASP N terminal Cnd1 PF12717.2 ETO01385.1 - 0.027 14.3 2.0 2.6 7.8 0.0 2.2 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF842 PF05811.8 ETO01385.1 - 0.38 10.2 5.0 0.43 10.0 0.7 2.4 1 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) MMS19_C PF12460.3 ETO01385.1 - 0.4 9.3 4.1 1.5 7.5 0.5 2.0 1 1 1 2 2 2 0 RNAPII transcription regulator C-terminal Tubulin PF00091.20 ETO01386.1 - 1.5e-37 129.5 0.4 1.3e-31 110.1 0.2 2.2 1 1 1 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO01386.1 - 2.3e-16 59.9 0.3 3.4e-11 43.2 0.0 2.4 1 1 1 2 2 2 2 Tubulin C-terminal domain Lipase_3 PF01764.20 ETO01386.1 - 0.018 14.6 0.0 0.097 12.2 0.0 2.0 2 0 0 2 2 2 0 Lipase (class 3) MRP-L20 PF12824.2 ETO01386.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 DUF2583 PF10762.4 ETO01387.1 - 0.32 11.1 7.0 0.44 10.6 0.9 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2583) DUF417 PF04224.7 ETO01387.1 - 1.7 7.9 5.7 3.5 6.9 3.7 1.8 1 1 1 2 2 2 0 Protein of unknown function, DUF417 DUF973 PF06157.6 ETO01387.1 - 4.4 6.1 12.5 0.96 8.3 6.4 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF973) P12 PF12669.2 ETO01387.1 - 5.3 7.3 0.0 5.3 7.3 0.0 3.1 3 0 0 3 3 3 0 Virus attachment protein p12 family Tetraspannin PF00335.15 ETO01387.1 - 6.3 6.0 7.7 9 5.5 5.4 1.4 1 0 0 1 1 1 0 Tetraspanin family DUF2619 PF10942.3 ETO01387.1 - 8.1 6.4 9.3 3.7 7.5 0.7 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF2619) DRMBL PF07522.9 ETO01388.1 - 1.9e-20 72.9 0.2 6e-19 68.1 0.1 2.5 1 1 0 1 1 1 1 DNA repair metallo-beta-lactamase RMMBL PF07521.7 ETO01388.1 - 9.8e-05 22.0 0.1 0.0002 21.1 0.0 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase PX PF00787.19 ETO01391.1 - 1.1e-07 31.5 0.9 2.5e-07 30.4 0.4 1.7 2 0 0 2 2 2 1 PX domain Ank_2 PF12796.2 ETO01391.1 - 0.0021 18.3 0.0 0.0041 17.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) DUF1388 PF07142.7 ETO01391.1 - 0.093 12.4 0.5 0.19 11.4 0.3 1.4 1 0 0 1 1 1 0 Repeat of unknown function (DUF1388) PPR_2 PF13041.1 ETO01392.1 - 0.0038 17.1 0.6 0.016 15.1 0.1 2.1 2 0 0 2 2 2 1 PPR repeat family PPR PF01535.15 ETO01392.1 - 0.17 11.9 2.0 0.49 10.5 0.0 2.5 3 0 0 3 3 3 0 PPR repeat WD40 PF00400.27 ETO01393.1 - 1.6e-194 623.7 44.5 1.1e-13 50.4 0.1 16.1 16 0 0 16 16 16 15 WD domain, G-beta repeat PQQ_2 PF13360.1 ETO01393.1 - 2.4e-25 89.4 12.8 2.3e-06 27.2 0.1 6.9 1 1 5 6 6 6 6 PQQ-like domain DUF1258 PF06869.7 ETO01393.1 - 2e-13 50.0 0.4 5.1 6.0 0.0 10.2 2 2 9 12 12 12 3 Protein of unknown function (DUF1258) PQQ_3 PF13570.1 ETO01393.1 - 1.4e-07 31.5 6.6 0.4 11.0 0.1 8.3 9 2 0 9 9 9 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO01393.1 - 2.3e-06 26.1 9.9 0.58 8.3 0.0 6.1 2 2 4 7 7 7 3 Cytochrome D1 heme domain PD40 PF07676.7 ETO01393.1 - 4e-05 23.1 22.3 9.5 6.0 0.0 10.9 11 0 0 11 11 11 1 WD40-like Beta Propeller Repeat PQQ PF01011.16 ETO01393.1 - 0.00011 21.5 0.0 11 5.7 0.0 6.6 8 0 0 8 8 8 1 PQQ enzyme repeat Pentapeptide_4 PF13599.1 ETO01393.1 - 0.00052 19.7 0.2 0.0015 18.3 0.2 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETO01393.1 - 0.002 17.3 0.1 0.0054 15.9 0.0 1.8 2 0 0 2 2 2 1 Pentapeptide repeats (8 copies) Proteasome_A_N PF10584.4 ETO01393.1 - 0.46 9.8 25.0 1.1e+02 2.2 0.0 10.9 11 0 0 11 11 11 0 Proteasome subunit A N-terminal signature PHR PF08005.7 ETO01394.1 - 5.5e-05 23.3 1.7 9.6e-05 22.5 1.2 1.5 1 1 0 1 1 1 1 PHR domain Cupin_8 PF13621.1 ETO01394.1 - 0.04 13.4 0.3 0.042 13.3 0.2 1.2 1 0 0 1 1 1 0 Cupin-like domain HSCB_C PF07743.8 ETO01395.1 - 5.6e-10 39.5 5.6 5.6e-10 39.5 3.9 1.8 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 ETO01395.1 - 5.5e-06 26.0 0.1 1.1e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain DZR PF12773.2 ETO01395.1 - 0.0027 17.4 0.2 0.0045 16.7 0.1 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 ETO01395.1 - 0.015 14.4 2.1 0.026 13.7 1.5 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 ETO01395.1 - 0.026 13.9 6.2 0.05 13.0 4.3 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Hrs_helical PF12210.3 ETO01395.1 - 0.036 14.3 0.9 0.093 12.9 0.2 1.9 1 1 1 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Tnp_zf-ribbon_2 PF13842.1 ETO01395.1 - 0.54 10.6 4.7 0.92 9.9 3.2 1.3 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon DUF3970 PF13113.1 ETO01395.1 - 4.9 6.9 6.6 2.7 7.7 0.1 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3970) N6_Mtase PF02384.11 ETO01396.1 - 4.3e-21 75.3 1.0 6.6e-20 71.4 0.1 2.4 1 1 1 2 2 2 1 N-6 DNA Methylase Methyltransf_26 PF13659.1 ETO01396.1 - 5.4e-07 29.6 0.0 2.1e-06 27.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 ETO01396.1 - 4.8e-05 23.0 0.0 0.048 13.2 0.0 2.4 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.1 ETO01396.1 - 0.0013 18.3 2.9 0.3 10.6 0.0 3.1 3 0 0 3 3 3 2 Methyltransferase domain Eco57I PF07669.6 ETO01396.1 - 0.0059 16.9 0.2 0.032 14.5 0.1 2.3 1 1 0 1 1 1 1 Eco57I restriction-modification methylase N6_N4_Mtase PF01555.13 ETO01396.1 - 0.039 13.4 5.9 0.083 12.3 4.1 1.5 1 1 0 1 1 1 0 DNA methylase MTS PF05175.9 ETO01396.1 - 0.093 12.1 0.0 0.27 10.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain DUF2415 PF10313.4 ETO01397.1 - 0.0067 16.0 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) TPR_12 PF13424.1 ETO01398.1 - 5.3e-45 151.2 9.6 2.3e-20 72.3 0.5 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO01398.1 - 4.3e-33 112.7 35.5 9.3e-14 50.8 4.7 4.4 1 1 4 5 5 5 5 TPR repeat TPR_1 PF00515.23 ETO01398.1 - 1e-28 97.6 31.5 7.2e-09 34.8 3.2 5.2 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETO01398.1 - 3.1e-27 93.6 0.1 2.2e-05 24.2 0.0 5.1 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETO01398.1 - 1.1e-26 90.5 22.2 2.8e-08 33.0 1.1 5.2 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.1 ETO01398.1 - 2.7e-22 76.7 28.9 1.2e-06 27.9 0.4 5.2 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.1 ETO01398.1 - 4.5e-21 72.9 5.8 0.00019 20.9 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO01398.1 - 1.3e-17 63.9 2.7 4.6e-06 27.1 0.3 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO01398.1 - 8.8e-13 47.6 0.0 0.0035 17.8 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat SNAP PF14938.1 ETO01398.1 - 1.1e-12 47.7 7.9 1.6e-08 34.0 1.2 2.0 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_6 PF13174.1 ETO01398.1 - 1.6e-12 47.0 4.5 0.0047 17.3 0.1 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO01398.1 - 1.2e-08 34.9 13.5 4.4e-05 23.5 3.8 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 ETO01398.1 - 2.7e-07 30.2 11.8 0.0017 18.3 1.7 5.5 4 2 0 4 4 4 2 Tetratricopeptide repeat MIT PF04212.13 ETO01398.1 - 5.8e-07 29.3 13.1 1.1 9.2 0.7 5.1 5 0 0 5 5 5 3 MIT (microtubule interacting and transport) domain DUF2225 PF09986.4 ETO01398.1 - 6e-07 29.1 12.8 0.006 16.0 0.2 3.2 1 1 2 3 3 3 3 Uncharacterized protein conserved in bacteria (DUF2225) TPR_19 PF14559.1 ETO01398.1 - 3.3e-06 27.3 3.5 0.037 14.3 0.1 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO01398.1 - 0.0003 19.9 2.3 1.5 8.1 0.0 4.6 5 0 0 5 5 5 1 SHNi-TPR DUF4254 PF14063.1 ETO01398.1 - 0.0022 17.5 0.3 0.32 10.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4254) Sel1 PF08238.7 ETO01398.1 - 0.0067 17.0 10.9 11 6.8 0.3 4.9 5 0 0 5 5 5 0 Sel1 repeat TPR_5 PF12688.2 ETO01398.1 - 0.008 16.2 1.0 0.7 9.9 0.0 3.1 2 1 1 3 3 2 1 Tetratrico peptide repeat 14-3-3 PF00244.15 ETO01398.1 - 0.016 14.2 8.6 0.036 13.1 0.2 2.9 1 1 0 2 2 2 0 14-3-3 protein OEP PF02321.13 ETO01398.1 - 0.065 12.8 1.2 7.5 6.0 0.3 2.5 2 0 0 2 2 2 0 Outer membrane efflux protein RPN7 PF10602.4 ETO01398.1 - 0.069 12.5 6.6 0.54 9.6 0.2 3.2 2 1 0 3 3 3 0 26S proteasome subunit RPN7 DUF627 PF04781.7 ETO01398.1 - 0.07 12.7 5.6 0.28 10.7 0.2 3.1 3 2 1 4 4 4 0 Protein of unknown function (DUF627) DBD_Tnp_Mut PF03108.10 ETO01398.1 - 0.072 12.6 0.9 1 8.9 0.1 2.8 3 0 0 3 3 3 0 MuDR family transposase SPO22 PF08631.5 ETO01398.1 - 0.084 11.9 6.2 0.34 9.9 0.4 2.3 2 1 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like Spore_III_AB PF09548.5 ETO01398.1 - 0.14 11.9 1.1 0.55 9.9 0.0 2.3 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) PPR PF01535.15 ETO01398.1 - 0.21 11.6 4.1 43 4.3 0.1 4.5 5 0 0 5 5 4 0 PPR repeat Sec5 PF15469.1 ETO01398.1 - 0.4 10.3 9.2 0.87 9.2 0.3 2.6 2 1 0 2 2 2 0 Exocyst complex component Sec5 TPR_21 PF09976.4 ETO01398.1 - 0.44 10.4 4.8 0.51 10.2 1.2 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat NSF PF02071.15 ETO01398.1 - 0.6 10.8 19.0 19 6.4 0.1 5.7 5 0 0 5 5 5 0 Aromatic-di-Alanine (AdAR) repeat Tho2 PF11262.3 ETO01398.1 - 0.62 9.0 4.8 0.15 11.0 0.3 2.0 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Vps39_1 PF10366.4 ETO01398.1 - 1.5 8.8 7.5 9.5 6.2 0.1 3.6 1 1 2 3 3 3 0 Vacuolar sorting protein 39 domain 1 TPR_3 PF07720.7 ETO01398.1 - 7.4 6.4 20.4 0.075 12.8 1.2 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat CIAPIN1 PF05093.8 ETO01399.1 - 0.24 11.4 1.7 0.47 10.5 1.2 1.7 1 1 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF3453 PF11935.3 ETO01400.1 - 0.039 13.3 0.2 0.042 13.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3453) Seadorna_Vp10 PF07322.6 ETO01400.1 - 0.16 11.2 1.1 0.14 11.3 0.8 1.1 1 0 0 1 1 1 0 Seadornavirus Vp10 WD40 PF00400.27 ETO01402.1 - 6.9e-22 76.4 1.3 1.2e-09 37.6 0.1 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO01402.1 - 4.3e-05 22.4 1.1 0.004 15.9 0.1 2.0 1 1 1 2 2 2 2 Nup133 N terminal like Nup160 PF11715.3 ETO01402.1 - 5.4e-05 21.5 0.3 0.0049 15.0 0.0 2.0 1 1 0 2 2 2 2 Nucleoporin Nup120/160 Cu-oxidase_2 PF07731.9 ETO01402.1 - 0.11 12.0 0.3 0.13 11.7 0.2 1.2 1 0 0 1 1 1 0 Multicopper oxidase NurA PF09376.5 ETO01403.1 - 1.1e-06 28.3 0.2 1.4e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 NurA domain Lar_restr_allev PF14354.1 ETO01403.1 - 0.0084 16.3 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 Restriction alleviation protein Lar Cys_rich_CPXG PF14255.1 ETO01403.1 - 0.015 15.1 1.3 0.026 14.3 0.9 1.4 1 0 0 1 1 1 0 Cysteine-rich CPXCG DUF2296 PF10058.4 ETO01403.1 - 0.024 14.3 0.5 0.047 13.4 0.3 1.5 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) DUF164 PF02591.10 ETO01403.1 - 0.033 14.0 0.4 3 7.7 0.0 2.4 2 0 0 2 2 2 0 Putative zinc ribbon domain CpXC PF14353.1 ETO01403.1 - 0.1 12.5 0.2 10 6.0 0.0 2.4 2 0 0 2 2 2 0 CpXC protein zf-C4_Topoisom PF01396.14 ETO01403.1 - 0.12 11.8 2.5 6.8 6.2 0.2 2.5 1 1 1 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zf-RING_3 PF14369.1 ETO01403.1 - 2.8 8.0 5.3 11 6.1 0.1 2.5 1 1 1 2 2 2 0 zinc-finger NACHT PF05729.7 ETO01405.1 - 4.6e-10 39.4 0.0 7.9e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO01405.1 - 9.5e-07 29.1 0.2 9.5e-07 29.1 0.2 2.5 2 2 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETO01405.1 - 3.1e-06 27.3 0.0 9.3e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ETO01405.1 - 3.3e-05 24.6 0.6 0.00025 21.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 ETO01405.1 - 0.0016 18.0 0.0 0.004 16.7 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 ATP_bind_2 PF03668.10 ETO01405.1 - 0.0018 17.4 0.0 0.0066 15.5 0.0 1.9 2 0 0 2 2 2 1 P-loop ATPase protein family AAA PF00004.24 ETO01405.1 - 0.0038 17.4 0.2 0.0083 16.3 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETO01405.1 - 0.0089 15.7 0.0 0.022 14.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 ETO01405.1 - 0.013 14.9 0.0 0.032 13.7 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 ETO01405.1 - 0.018 15.1 4.5 0.044 13.9 0.1 2.9 1 1 1 2 2 2 0 RNA helicase AAA_33 PF13671.1 ETO01405.1 - 0.021 14.6 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 ETO01405.1 - 0.022 13.9 0.0 0.039 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 ETO01405.1 - 0.029 13.4 0.0 0.052 12.6 0.0 1.6 1 1 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 ETO01405.1 - 0.038 14.2 1.4 0.057 13.7 0.5 1.7 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 ETO01405.1 - 0.068 13.1 0.2 0.63 9.9 0.0 2.1 1 1 1 2 2 2 0 AAA ATPase domain RecX PF02631.11 ETO01405.1 - 0.13 12.4 4.1 14 5.8 0.0 3.2 3 0 0 3 3 3 0 RecX family AAA_29 PF13555.1 ETO01405.1 - 0.14 11.6 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IL15 PF02372.10 ETO01405.1 - 2.3 8.0 7.3 0.3 10.8 1.6 2.1 2 1 1 3 3 2 0 Interleukin 15 AAA_21 PF13304.1 ETO01405.1 - 2.8 7.8 14.4 0.25 11.2 4.5 2.7 1 1 2 3 3 3 0 AAA domain Yippee-Mis18 PF03226.9 ETO01406.1 - 1.3e-10 41.1 5.3 3.5e-10 39.7 3.7 1.7 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Myc_N PF01056.13 ETO01406.1 - 0.065 12.3 18.9 0.65 9.1 6.3 2.1 2 0 0 2 2 2 0 Myc amino-terminal region BUD22 PF09073.5 ETO01406.1 - 0.1 11.6 21.8 0.075 12.1 6.2 2.1 2 0 0 2 2 2 0 BUD22 Sigma70_ner PF04546.8 ETO01406.1 - 0.11 12.1 19.4 0.33 10.5 4.0 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region CDC45 PF02724.9 ETO01406.1 - 0.42 8.5 23.7 0.02 12.9 3.8 2.2 2 0 0 2 2 2 0 CDC45-like protein Daxx PF03344.10 ETO01406.1 - 0.5 8.7 27.0 0.75 8.2 4.7 2.0 2 0 0 2 2 2 0 Daxx Family RPOL_N PF14700.1 ETO01406.1 - 2.4 7.3 6.8 8.3 5.5 1.0 2.5 2 1 1 3 3 3 0 DNA-directed RNA polymerase N-terminal SAPS PF04499.10 ETO01406.1 - 2.8 6.4 14.3 0.38 9.3 2.7 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Nop14 PF04147.7 ETO01406.1 - 6.6 4.5 29.1 0.26 9.1 3.6 2.1 2 0 0 2 2 2 0 Nop14-like family BTV_NS2 PF04514.7 ETO01406.1 - 9.2 5.0 18.1 0.39 9.5 2.9 2.1 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 Sporozoite_P67 PF05642.6 ETO01406.1 - 9.8 3.8 21.4 1.9 6.2 4.9 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen AP-5_subunit_s1 PF15001.1 ETO01407.1 - 0.17 11.8 1.8 0.48 10.3 1.3 1.8 1 1 0 1 1 1 0 AP-5 complex subunit sigma-1 RDD PF06271.7 ETO01408.1 - 0.025 14.4 2.1 0.051 13.4 1.4 1.5 1 0 0 1 1 1 0 RDD family WD40 PF00400.27 ETO01408.1 - 0.097 12.5 0.0 0.31 11.0 0.0 1.9 1 0 0 1 1 1 0 WD domain, G-beta repeat zf-TRAF PF02176.13 ETO01409.1 - 3.1e-05 24.2 5.2 3.1e-05 24.2 3.6 2.6 2 1 0 2 2 2 1 TRAF-type zinc finger Spc7 PF08317.6 ETO01409.1 - 0.00029 19.6 20.2 0.00046 18.9 14.0 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Geminin PF07412.7 ETO01409.1 - 0.013 15.2 3.7 0.013 15.2 2.6 3.8 2 1 2 4 4 4 0 Geminin DUF641 PF04859.7 ETO01409.1 - 0.33 10.6 17.1 1.8 8.3 3.5 3.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) zf-C3HC4_2 PF13923.1 ETO01409.1 - 1.8 8.6 11.6 0.52 10.3 0.7 3.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) bZIP_1 PF00170.16 ETO01409.1 - 7.5 6.6 16.6 8.9 6.3 3.9 3.5 1 1 2 3 3 3 0 bZIP transcription factor DUF4140 PF13600.1 ETO01409.1 - 9.1 6.7 13.4 29 5.1 0.3 3.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) LMBR1 PF04791.11 ETO01418.1 - 0.73 8.3 7.3 0.71 8.3 5.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2201_N PF13203.1 ETO01418.1 - 3.9 6.5 10.7 5.8 5.9 7.4 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Ras PF00071.17 ETO01419.1 - 2.1e-06 27.2 0.0 2.5e-06 26.9 0.0 1.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 ETO01419.1 - 0.0086 16.5 0.2 0.03 14.8 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein BLVR PF06375.6 ETO01419.1 - 0.066 13.0 7.9 0.1 12.4 5.5 1.4 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) DUF3446 PF11928.3 ETO01420.1 - 0.0037 17.4 0.9 0.21 11.8 1.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3446) SR-25 PF10500.4 ETO01420.1 - 0.079 12.4 7.3 0.1 12.0 5.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RRM_1 PF00076.17 ETO01421.1 - 0.0001 21.8 0.1 0.00045 19.8 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO01421.1 - 0.0002 21.2 0.0 0.00048 20.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) HGD-D PF06050.8 ETO01421.1 - 0.025 13.4 0.2 0.036 12.8 0.1 1.3 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component DUF1831 PF08866.5 ETO01421.1 - 0.041 14.1 1.0 0.067 13.4 0.7 1.3 1 0 0 1 1 1 0 Putative amino acid metabolism DUF479 PF04336.7 ETO01421.1 - 0.27 11.3 2.8 0.45 10.6 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF479 AAA_23 PF13476.1 ETO01421.1 - 2.1 8.5 14.2 3 8.1 9.9 1.3 1 0 0 1 1 1 0 AAA domain Cauli_AT PF03233.8 ETO01421.1 - 3.2 7.4 9.8 1.1 8.9 4.7 1.8 2 1 0 2 2 2 0 Aphid transmission protein TMPIT PF07851.8 ETO01421.1 - 4.5 6.2 7.4 6.9 5.6 5.2 1.3 1 0 0 1 1 1 0 TMPIT-like protein Syntaxin-6_N PF09177.6 ETO01421.1 - 7.3 7.0 10.3 1.7 9.0 4.0 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Zip PF02535.17 ETO01422.1 - 0.076 12.0 0.5 0.15 11.0 0.3 1.5 1 1 0 1 1 1 0 ZIP Zinc transporter RCR PF12273.3 ETO01422.1 - 0.24 11.9 3.0 0.36 11.3 2.1 1.2 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red ERM PF00769.14 ETO01423.1 - 0.0038 16.8 40.6 0.0061 16.1 28.1 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF3584 PF12128.3 ETO01423.1 - 0.043 11.1 41.6 0.063 10.6 28.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Atg14 PF10186.4 ETO01423.1 - 0.66 8.8 47.4 0.11 11.3 29.1 1.9 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1675 PF07897.6 ETO01423.1 - 0.73 9.6 13.5 0.77 9.5 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) SprA-related PF12118.3 ETO01423.1 - 0.99 8.6 32.3 1.5 8.0 22.4 1.2 1 0 0 1 1 1 0 SprA-related family Fusion_gly PF00523.13 ETO01423.1 - 1.8 6.5 18.0 1.9 6.4 7.7 2.1 1 1 1 2 2 2 0 Fusion glycoprotein F0 Med15 PF09606.5 ETO01423.1 - 2.5 6.1 24.6 2.7 6.0 17.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Parvo_coat PF00740.13 ETO01423.1 - 2.7 6.8 15.7 3.1 6.6 10.9 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 HOOK PF05622.7 ETO01423.1 - 6.4 4.4 44.0 8.9 3.9 30.5 1.1 1 0 0 1 1 1 0 HOOK protein DNA_ligase_A_C PF04679.10 ETO01423.1 - 7.5 7.0 6.4 41 4.6 4.4 2.3 1 1 0 1 1 1 0 ATP dependent DNA ligase C terminal region Phasin PF05597.6 ETO01423.1 - 7.7 6.2 33.9 0.038 13.7 10.2 2.3 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) CALCOCO1 PF07888.6 ETO01423.1 - 9.6 4.3 34.2 13 3.9 23.7 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like PLRV_ORF5 PF01690.12 ETO01423.1 - 10 5.1 21.4 11 5.0 14.8 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein TMEM138 PF14935.1 ETO01425.1 - 0.025 14.9 1.4 0.042 14.1 1.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 138 Synaptobrevin PF00957.16 ETO01425.1 - 0.064 12.8 1.0 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 Synaptobrevin ER_lumen_recept PF00810.13 ETO01425.1 - 0.13 12.7 2.0 0.21 12.0 1.4 1.3 1 0 0 1 1 1 0 ER lumen protein retaining receptor Mob_Pre PF01076.14 ETO01426.1 - 0.23 11.0 3.2 0.12 11.9 0.8 1.6 2 0 0 2 2 2 0 Plasmid recombination enzyme DUF1777 PF08648.7 ETO01428.1 - 0.0039 16.9 9.3 0.0041 16.8 6.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) Pox_Ag35 PF03286.9 ETO01428.1 - 0.0051 16.3 7.4 0.0061 16.0 5.1 1.1 1 0 0 1 1 1 1 Pox virus Ag35 surface protein Pex14_N PF04695.8 ETO01428.1 - 0.03 14.3 8.4 0.043 13.8 5.8 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Corona_nucleoca PF00937.13 ETO01428.1 - 0.073 12.0 18.5 0.098 11.5 12.8 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF4048 PF13257.1 ETO01428.1 - 0.16 11.6 12.5 0.17 11.4 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4048) Menin PF05053.8 ETO01428.1 - 0.34 9.0 11.4 0.37 8.9 7.9 1.0 1 0 0 1 1 1 0 Menin Period_C PF12114.3 ETO01428.1 - 0.4 10.2 10.0 0.43 10.1 6.9 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF4614 PF15391.1 ETO01428.1 - 0.43 10.3 8.7 0.5 10.1 6.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) YscJ_FliF_C PF08345.6 ETO01428.1 - 0.5 10.3 19.0 0.63 9.9 13.2 1.1 1 0 0 1 1 1 0 Flagellar M-ring protein C-terminal Tankyrase_bdg_C PF15327.1 ETO01428.1 - 0.75 9.9 9.8 0.94 9.6 6.8 1.1 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain Secretin_N_2 PF07655.8 ETO01428.1 - 0.81 10.1 27.3 1.2 9.5 18.9 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Hid1 PF12722.2 ETO01428.1 - 1.4 6.5 12.6 1.4 6.5 8.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RP-C_C PF11800.3 ETO01428.1 - 1.4 8.5 6.0 1.6 8.3 4.2 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Pox_E2-like PF04497.7 ETO01428.1 - 1.7 6.5 5.3 1.7 6.5 3.7 1.0 1 0 0 1 1 1 0 Poxviridae protein Transformer PF06495.6 ETO01428.1 - 1.7 8.4 12.1 2.1 8.1 8.4 1.2 1 0 0 1 1 1 0 Fruit fly transformer protein Gag_spuma PF03276.9 ETO01428.1 - 1.8 6.7 14.1 2.1 6.5 9.8 1.0 1 0 0 1 1 1 0 Spumavirus gag protein DUF4551 PF15087.1 ETO01428.1 - 2 6.6 8.5 2.2 6.5 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Astro_capsid PF03115.9 ETO01428.1 - 2.1 6.5 14.4 2.3 6.3 9.9 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Apis_Csd PF11671.3 ETO01428.1 - 3.6 7.3 28.0 4.4 7.0 19.2 1.4 1 1 0 1 1 1 0 Complementary sex determiner protein Exonuc_VII_L PF02601.10 ETO01428.1 - 4.9 6.2 9.0 5.5 6.0 6.2 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2956 PF11169.3 ETO01428.1 - 5.1 7.1 7.1 8.6 6.3 4.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2956) Rubella_Capsid PF05750.6 ETO01428.1 - 7.4 5.8 6.4 8.9 5.6 4.5 1.0 1 0 0 1 1 1 0 Rubella capsid protein NPR3 PF03666.8 ETO01428.1 - 10 4.5 14.9 12 4.2 10.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 UPF0564 PF10595.4 ETO01429.1 - 0.13 11.1 8.7 0.17 10.8 6.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 zf-MIZ PF02891.15 ETO01430.1 - 0.046 13.2 1.1 0.058 12.9 0.3 1.6 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Kelch_1 PF01344.20 ETO01431.1 - 7.1e-06 25.4 2.0 0.00075 18.9 0.3 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 ETO01431.1 - 3e-05 23.8 2.0 1.1 9.3 0.1 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO01431.1 - 0.0001 22.3 2.1 0.014 15.5 0.2 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO01431.1 - 0.00097 18.8 2.7 0.21 11.4 0.2 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 ETO01431.1 - 0.0077 16.3 0.1 0.3 11.3 0.0 3.3 4 0 0 4 4 4 1 Galactose oxidase, central domain TPR_8 PF13181.1 ETO01432.1 - 1.1e-07 31.0 0.2 3.3e-07 29.5 0.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO01432.1 - 8.5e-06 25.6 0.0 1.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO01432.1 - 1.2e-05 24.8 0.0 2.8e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO01432.1 - 7.2e-05 22.2 0.9 0.00013 21.4 0.1 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO01432.1 - 0.0031 17.8 0.0 0.087 13.3 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat A2M_comp PF07678.9 ETO01432.1 - 0.027 13.6 0.1 0.036 13.3 0.1 1.3 1 0 0 1 1 1 0 A-macroglobulin complement component DUF3818 PF12825.2 ETO01432.1 - 0.041 12.5 3.6 0.051 12.2 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) Collagen_bind_2 PF12904.2 ETO01432.1 - 0.045 13.5 0.7 0.085 12.6 0.5 1.6 1 0 0 1 1 1 0 Putative collagen-binding domain of a collagenase TPR_11 PF13414.1 ETO01432.1 - 0.059 13.0 0.1 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 TPR repeat Terminase_5 PF06056.7 ETO01432.1 - 0.06 12.9 0.3 0.16 11.5 0.2 1.6 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) DUF2719 PF10891.3 ETO01432.1 - 0.088 12.5 0.2 0.64 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2719) DUF1669 PF07894.7 ETO01434.1 - 0.41 9.7 2.5 0.49 9.5 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) MIP-T3 PF10243.4 ETO01434.1 - 2 6.7 23.1 2.4 6.5 16.0 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF3513 PF12026.3 ETO01434.1 - 5 6.6 10.5 5.7 6.4 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) NARP1 PF12569.3 ETO01434.1 - 8.5 4.9 16.3 9 4.9 11.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 MRP_L53 PF10780.4 ETO01435.1 - 0.14 12.1 0.1 0.18 11.7 0.1 1.2 1 0 0 1 1 1 0 39S ribosomal protein L53/MRP-L53 DUF2659 PF10858.3 ETO01435.1 - 0.25 10.7 3.6 0.24 10.7 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2659) ETRAMP PF09716.5 ETO01435.1 - 0.56 10.1 3.1 0.68 9.9 2.2 1.1 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) PseudoU_synth_2 PF00849.17 ETO01436.1 - 0.011 15.5 0.3 0.013 15.3 0.2 1.2 1 1 0 1 1 1 0 RNA pseudouridylate synthase Ank_2 PF12796.2 ETO01437.1 - 5.9e-10 39.3 0.1 8.1e-10 38.9 0.1 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO01437.1 - 4.5e-09 35.6 0.0 0.00049 20.0 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.25 ETO01437.1 - 5.4e-09 35.4 0.1 3.4e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 ETO01437.1 - 5e-08 33.2 0.1 1e-07 32.2 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO01437.1 - 1.9e-07 31.0 0.1 4.5e-06 26.7 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) ACCA PF03255.9 ETO01437.1 - 0.0062 16.0 0.1 0.0082 15.7 0.1 1.1 1 0 0 1 1 1 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF1843 PF08898.5 ETO01437.1 - 0.066 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) NIF PF03031.13 ETO01437.1 - 0.11 12.0 1.3 0.18 11.4 0.9 1.2 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase HEAT PF02985.17 ETO01439.1 - 2.3e-14 52.0 0.0 0.00099 18.9 0.0 3.2 3 0 0 3 3 3 3 HEAT repeat HEAT_2 PF13646.1 ETO01439.1 - 9.5e-12 45.0 0.0 6.8e-06 26.2 0.0 2.4 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 ETO01439.1 - 8.7e-09 35.6 0.0 0.017 15.5 0.0 3.0 2 1 1 3 3 3 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 ETO01439.1 - 2.9e-06 27.5 0.2 0.0038 17.5 0.1 2.7 1 1 2 3 3 3 3 Vacuolar 14 Fab1-binding region TIP120 PF08623.5 ETO01439.1 - 3.2e-05 23.5 2.4 0.00073 19.1 0.5 2.6 1 1 2 3 3 3 2 TATA-binding protein interacting (TIP20) Cnd1 PF12717.2 ETO01439.1 - 0.0001 22.2 0.2 0.00014 21.7 0.1 1.2 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 KAP PF05804.7 ETO01439.1 - 0.00033 18.7 2.1 0.59 7.9 0.1 3.0 1 1 2 3 3 3 2 Kinesin-associated protein (KAP) Adaptin_N PF01602.15 ETO01439.1 - 0.0012 17.2 0.3 0.0013 17.1 0.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region DUF2435 PF10363.4 ETO01439.1 - 0.0021 17.9 0.1 0.007 16.2 0.1 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2435) DUF3554 PF12074.3 ETO01439.1 - 0.0031 17.0 0.1 0.36 10.2 0.1 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF3554) CRM1_C PF08767.6 ETO01439.1 - 0.0039 16.1 0.1 0.51 9.2 0.0 2.0 2 0 0 2 2 2 1 CRM1 C terminal CLASP_N PF12348.3 ETO01439.1 - 0.011 15.1 0.1 0.016 14.5 0.1 1.3 1 0 0 1 1 1 0 CLASP N terminal NLE PF08154.7 ETO01439.1 - 0.014 15.3 0.2 3 7.9 0.0 2.9 2 1 1 3 3 3 0 NLE (NUC135) domain MOR2-PAG1_N PF14222.1 ETO01439.1 - 0.022 13.4 0.0 0.81 8.2 0.0 2.3 1 1 1 2 2 2 0 Cell morphogenesis N-terminal ThylakoidFormat PF11264.3 ETO01439.1 - 0.038 13.6 0.2 1.4 8.4 0.1 2.0 1 1 1 2 2 2 0 Thylakoid formation protein DUF2758 PF10957.3 ETO01439.1 - 0.038 13.8 1.6 0.68 9.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2758) CAAP1 PF15335.1 ETO01439.1 - 0.058 13.6 1.1 20 5.4 0.0 3.1 1 1 2 3 3 3 0 Caspase activity and apoptosis inhibitor 1 DUF2608 PF11019.3 ETO01439.1 - 0.066 12.2 0.2 0.26 10.2 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2608) PAS_10 PF13596.1 ETO01439.1 - 0.087 13.1 0.2 8.8 6.6 0.0 2.4 1 1 1 2 2 2 0 PAS domain DUF3596 PF12167.3 ETO01439.1 - 0.09 12.3 0.0 5.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3596) DUF1307 PF06998.6 ETO01439.1 - 0.097 12.7 0.5 0.13 12.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1307) DUF3810 PF12725.2 ETO01439.1 - 0.099 11.5 0.1 1.4 7.7 0.1 1.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3810) DUF2489 PF10675.4 ETO01439.1 - 0.12 12.0 1.2 6 6.5 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2489) MA3 PF02847.12 ETO01439.1 - 0.12 12.0 0.9 0.34 10.6 0.1 1.8 1 1 1 2 2 2 0 MA3 domain RPT PF13446.1 ETO01439.1 - 0.14 11.5 0.2 5.7 6.4 0.0 2.5 2 1 1 3 3 3 0 A repeated domain in UCH-protein DUF3944 PF13099.1 ETO01439.1 - 1.9 8.0 9.0 3.9 7.0 0.0 3.5 4 1 0 4 4 3 0 Domain of unknown function (DUF3944) WD40 PF00400.27 ETO01442.1 - 1.1e-09 37.8 0.0 4.5e-05 23.1 0.1 2.7 3 0 0 3 3 3 2 WD domain, G-beta repeat FmdE PF02663.9 ETO01442.1 - 0.021 14.7 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon HEAT_2 PF13646.1 ETO01443.1 - 0.00046 20.4 0.0 0.27 11.5 0.0 2.8 2 1 0 2 2 2 2 HEAT repeats Flagellin_N PF00669.15 ETO01443.1 - 0.035 13.8 0.2 0.097 12.4 0.1 1.7 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region TPR_12 PF13424.1 ETO01444.1 - 3.4e-81 267.2 5.9 5.3e-29 99.9 0.3 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO01444.1 - 1.8e-60 199.2 0.0 1.2e-10 40.9 0.0 6.0 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETO01444.1 - 1.4e-54 179.5 34.1 1.3e-11 43.5 1.3 6.2 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_11 PF13414.1 ETO01444.1 - 1.5e-52 175.0 24.0 1.5e-20 72.6 2.2 4.1 2 1 1 4 4 4 4 TPR repeat TPR_7 PF13176.1 ETO01444.1 - 7.7e-50 162.8 2.4 2.9e-09 36.0 0.0 6.1 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.12 ETO01444.1 - 1e-42 140.6 27.9 1.1e-08 34.2 0.6 6.2 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETO01444.1 - 1.9e-40 133.6 45.5 8.7e-09 34.5 2.0 6.2 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.1 ETO01444.1 - 2.8e-29 98.8 13.6 4.7e-05 23.2 0.1 7.3 6 3 0 6 6 6 6 Tetratricopeptide repeat TPR_16 PF13432.1 ETO01444.1 - 2.4e-24 85.3 0.0 4.1e-07 30.4 0.0 5.6 1 1 5 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 ETO01444.1 - 2.5e-20 71.1 0.0 0.011 16.2 0.0 6.4 2 2 4 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.1 ETO01444.1 - 4.7e-17 61.1 5.9 0.041 14.3 0.0 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 ETO01444.1 - 1.2e-16 60.7 1.4 1.3e-05 25.4 0.1 4.1 2 1 2 4 4 4 4 Tetratricopeptide repeat Apc3 PF12895.2 ETO01444.1 - 2.3e-14 53.2 15.4 2.5e-06 27.5 2.3 4.9 1 1 4 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 ETO01444.1 - 3.5e-13 49.2 24.7 0.00065 19.5 0.4 5.9 5 1 1 6 6 6 4 MIT (microtubule interacting and transport) domain PPR PF01535.15 ETO01444.1 - 2.9e-10 39.4 12.5 0.0067 16.3 0.1 5.7 6 0 0 6 6 6 3 PPR repeat SHNi-TPR PF10516.4 ETO01444.1 - 8.6e-10 37.6 0.1 0.052 12.7 0.0 6.1 6 0 0 6 6 6 1 SHNi-TPR SNAP PF14938.1 ETO01444.1 - 1.6e-09 37.3 9.8 2.4e-08 33.5 2.8 3.5 1 1 2 3 3 3 2 Soluble NSF attachment protein, SNAP TPR_3 PF07720.7 ETO01444.1 - 2.2e-09 36.9 22.1 0.022 14.5 0.6 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat RPN7 PF10602.4 ETO01444.1 - 4.8e-06 26.0 11.6 0.35 10.2 0.1 4.9 2 2 3 5 5 5 3 26S proteasome subunit RPN7 Sel1 PF08238.7 ETO01444.1 - 1.2e-05 25.7 15.4 0.35 11.5 0.1 6.0 6 0 0 6 6 6 2 Sel1 repeat Pep3_Vps18 PF05131.9 ETO01444.1 - 2.6e-05 23.7 7.9 2.6 7.4 0.0 5.4 5 1 0 6 6 6 1 Pep3/Vps18/deep orange family TPR_9 PF13371.1 ETO01444.1 - 3.5e-05 23.5 0.0 0.07 12.9 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO01444.1 - 0.0004 20.1 18.6 2.1 8.2 0.1 6.1 6 0 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat DUF2225 PF09986.4 ETO01444.1 - 0.00074 19.0 6.9 0.038 13.4 1.1 2.9 1 1 2 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) PPR_2 PF13041.1 ETO01444.1 - 0.0013 18.6 5.9 4.7 7.2 0.1 4.4 5 0 0 5 5 4 0 PPR repeat family DUF627 PF04781.7 ETO01444.1 - 0.0021 17.6 12.1 2.9 7.5 0.0 5.5 1 1 5 6 6 6 1 Protein of unknown function (DUF627) Clathrin PF00637.15 ETO01444.1 - 0.0022 17.6 11.6 0.71 9.4 1.0 5.2 1 1 1 3 3 3 1 Region in Clathrin and VPS KH_4 PF13083.1 ETO01444.1 - 0.0028 17.2 0.1 0.63 9.7 0.0 3.2 2 2 2 4 4 4 1 KH domain TPR_5 PF12688.2 ETO01444.1 - 0.0063 16.5 0.5 11 6.1 0.0 3.6 3 1 1 4 4 4 0 Tetratrico peptide repeat Mob_Pre PF01076.14 ETO01444.1 - 0.019 14.6 5.7 0.17 11.5 0.1 3.2 1 1 2 3 3 3 0 Plasmid recombination enzyme DUF3568 PF12092.3 ETO01444.1 - 0.026 14.2 0.2 4.3 7.0 0.0 3.7 1 1 2 4 4 4 0 Protein of unknown function (DUF3568) EzrA PF06160.7 ETO01444.1 - 0.035 12.2 6.3 6.9 4.7 0.1 4.6 4 1 1 5 5 5 0 Septation ring formation regulator, EzrA Ribosomal_S7 PF00177.16 ETO01444.1 - 0.079 12.5 0.5 2.4 7.7 0.1 3.0 1 1 1 2 2 2 0 Ribosomal protein S7p/S5e DUF386 PF04074.7 ETO01444.1 - 0.15 11.5 1.3 0.51 9.8 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF386) TPR_21 PF09976.4 ETO01444.1 - 0.18 11.7 1.6 15 5.5 0.2 3.3 4 1 0 4 4 3 0 Tetratricopeptide repeat Intimin_C PF07979.6 ETO01444.1 - 0.19 11.9 6.5 1.6 8.9 0.1 3.5 1 1 2 3 3 3 0 Intimin C-type lectin domain Lumazine_bd PF12870.2 ETO01444.1 - 0.6 10.1 6.7 17 5.4 0.1 4.1 5 0 0 5 5 4 0 Lumazine-binding domain SPO22 PF08631.5 ETO01444.1 - 0.79 8.7 6.7 41 3.1 0.1 4.2 4 0 0 4 4 4 0 Meiosis protein SPO22/ZIP4 like LAGLIDADG_3 PF14528.1 ETO01444.1 - 1.3 9.2 4.3 64 3.8 0.0 3.9 4 1 1 5 5 3 0 LAGLIDADG-like domain AAA_5 PF07728.9 ETO01447.1 - 3.4e-05 23.5 0.0 7.4e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 ETO01447.1 - 8.7e-05 22.8 0.0 0.0002 21.6 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA PF00004.24 ETO01447.1 - 0.00029 21.0 0.0 0.00065 19.9 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETO01447.1 - 0.00037 20.6 0.2 0.012 15.7 0.1 2.2 1 1 0 2 2 2 1 AAA domain Miro PF08477.8 ETO01447.1 - 0.00041 20.8 0.0 0.0029 18.1 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein NACHT PF05729.7 ETO01447.1 - 0.0032 17.1 0.0 0.21 11.2 0.0 2.6 2 1 0 2 2 2 1 NACHT domain Arch_ATPase PF01637.13 ETO01447.1 - 0.0048 16.6 0.1 0.013 15.2 0.1 1.8 1 1 0 1 1 1 1 Archaeal ATPase DUF258 PF03193.11 ETO01447.1 - 0.0049 16.0 0.0 0.0075 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 ETO01447.1 - 0.013 15.3 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 ETO01447.1 - 0.026 14.5 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DBB PF14545.1 ETO01447.1 - 0.043 13.3 0.1 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 Dof, BCAP, and BANK (DBB) motif, AAA_18 PF13238.1 ETO01447.1 - 0.07 13.4 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 ETO01447.1 - 0.087 12.2 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 ETO01447.1 - 0.1 12.7 0.1 0.21 11.7 0.0 1.7 1 1 0 1 1 1 0 RNA helicase ATP-synt_ab PF00006.20 ETO01447.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Peptidase_C12 PF01088.16 ETO01449.1 - 0.0032 16.6 0.3 0.0034 16.5 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Atrophin-1 PF03154.10 ETO01449.1 - 3.5 5.6 4.9 3.8 5.5 3.4 1.0 1 0 0 1 1 1 0 Atrophin-1 family WD40 PF00400.27 ETO01450.1 - 3.1e-23 80.7 5.9 2e-10 40.1 0.2 3.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO01450.1 - 2.6e-05 22.5 2.9 0.23 9.5 0.0 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 WD40 PF00400.27 ETO01451.1 - 2e-50 166.9 18.0 2.6e-10 39.7 0.1 7.0 8 0 0 8 8 8 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO01451.1 - 1e-08 33.8 4.3 0.00015 20.0 0.1 4.0 2 2 1 3 3 3 3 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO01451.1 - 1e-07 32.1 2.5 5e-07 29.9 1.7 2.3 1 0 0 1 1 1 1 TRAF-type zinc finger DUF3601 PF12208.3 ETO01451.1 - 3.1e-05 23.8 0.3 6.3 6.8 0.0 5.2 4 1 2 6 6 6 2 Domain of unknown function (DUF3601) DUF1068 PF06364.7 ETO01451.1 - 0.083 12.4 7.6 0.16 11.5 5.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) COG2 PF06148.6 ETO01451.1 - 8.9 6.1 18.1 2.8 7.8 9.6 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_12 PF13424.1 ETO01452.1 - 8.1e-26 89.7 0.1 8.1e-19 67.3 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO01452.1 - 9.1e-14 50.8 0.0 0.00031 20.5 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO01452.1 - 1.1e-13 50.0 9.2 2.3e-05 23.7 0.5 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO01452.1 - 5.6e-13 48.3 1.7 1e-11 44.2 0.5 2.5 2 0 0 2 2 2 1 TPR repeat TPR_8 PF13181.1 ETO01452.1 - 2.4e-12 45.7 7.7 0.002 17.7 0.4 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO01452.1 - 1.6e-11 43.0 0.4 0.00088 18.8 0.0 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO01452.1 - 1.2e-09 37.3 4.1 0.01 15.6 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat Kelch_6 PF13964.1 ETO01452.1 - 0.00075 19.5 6.8 0.42 10.8 0.0 4.7 3 1 1 4 4 4 2 Kelch motif MIT PF04212.13 ETO01452.1 - 0.0034 17.2 1.0 2 8.3 0.0 3.3 2 1 1 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_17 PF13431.1 ETO01452.1 - 0.0035 17.4 1.1 12 6.3 0.1 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Kelch_5 PF13854.1 ETO01452.1 - 0.0068 16.3 0.1 1.1 9.3 0.1 3.8 3 0 0 3 3 3 1 Kelch motif SHNi-TPR PF10516.4 ETO01452.1 - 0.067 12.4 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 SHNi-TPR TPR_14 PF13428.1 ETO01452.1 - 0.14 12.8 0.0 12 6.8 0.0 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat Kelch_4 PF13418.1 ETO01452.1 - 0.2 11.4 5.6 9.8 6.0 0.0 4.1 4 1 0 4 4 4 0 Galactose oxidase, central domain Apc3 PF12895.2 ETO01452.1 - 0.93 9.6 5.7 0.53 10.4 1.1 2.9 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4200 PF13863.1 ETO01453.1 - 0.024 14.5 3.7 0.1 12.5 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) CENP-F_leu_zip PF10473.4 ETO01453.1 - 0.077 12.8 5.1 0.82 9.5 0.1 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.16 ETO01453.1 - 0.22 11.4 7.4 0.22 11.5 2.5 2.2 2 0 0 2 2 2 0 bZIP transcription factor DivIC PF04977.10 ETO01453.1 - 0.28 10.6 5.9 0.34 10.4 2.8 1.9 2 0 0 2 2 2 0 Septum formation initiator DUF3573 PF12097.3 ETO01453.1 - 0.33 9.5 2.7 0.34 9.4 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) TSC22 PF01166.13 ETO01453.1 - 0.87 9.6 5.7 2 8.4 1.1 2.8 2 1 1 3 3 3 0 TSC-22/dip/bun family bZIP_2 PF07716.10 ETO01453.1 - 0.91 9.3 12.5 2.5 8.0 5.3 2.3 2 0 0 2 2 2 0 Basic region leucine zipper Dev_Cell_Death PF10539.4 ETO01454.1 - 0.08 12.4 0.1 0.1 12.1 0.1 1.3 1 1 0 1 1 1 0 Development and cell death domain DUF3294 PF07957.6 ETO01455.1 - 0.0073 15.8 0.5 0.0073 15.8 0.3 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3294) PAP_central PF04928.12 ETO01455.1 - 0.076 11.8 0.5 0.13 11.1 0.4 1.4 1 0 0 1 1 1 0 Poly(A) polymerase central domain Kelch_4 PF13418.1 ETO01457.1 - 0.088 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Galactose oxidase, central domain RraB PF06877.6 ETO01457.1 - 0.12 12.9 3.2 0.51 11.0 0.1 2.2 1 1 1 2 2 2 0 Regulator of ribonuclease activity B DUF809 PF05663.6 ETO01457.1 - 0.25 11.2 4.9 0.31 10.9 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF809) DUF342 PF03961.8 ETO01457.1 - 0.78 8.0 6.3 0.86 7.9 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Viral_P18 PF04521.8 ETO01457.1 - 9.3 5.7 8.0 15 5.0 0.3 2.1 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Aminotran_1_2 PF00155.16 ETO01458.1 - 2.8e-08 33.0 0.2 2e-07 30.3 0.1 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II ADH_zinc_N PF00107.21 ETO01459.1 - 5.8e-16 58.2 0.0 3.2e-15 55.8 0.0 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETO01459.1 - 1.7e-11 45.0 0.0 4.8e-11 43.6 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETO01459.1 - 8.8e-07 28.6 0.3 2.9e-05 23.7 0.0 2.5 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Thioredoxin PF00085.15 ETO01460.1 - 6.6e-18 64.3 0.1 1.1e-17 63.6 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 ETO01460.1 - 0.0051 16.9 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 ETO01460.1 - 0.0078 16.4 0.1 0.025 14.7 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain AAA_7 PF12775.2 ETO01460.1 - 0.035 13.1 0.1 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 DSBA PF01323.15 ETO01460.1 - 0.075 12.5 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 DSBA-like thioredoxin domain TLD PF07534.11 ETO01461.1 - 9e-13 48.4 1.3 2.2e-11 43.9 0.1 3.3 2 1 0 2 2 2 1 TLD WD40 PF00400.27 ETO01462.1 - 4.3e-11 42.2 0.1 8.2e-11 41.3 0.1 1.5 2 0 0 2 2 2 1 WD domain, G-beta repeat OLF PF02191.11 ETO01462.1 - 0.1 11.8 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Olfactomedin-like domain DEAD PF00270.24 ETO01463.1 - 5.8e-42 143.0 0.1 9.2e-42 142.3 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETO01463.1 - 7e-27 93.1 0.1 1.5e-26 92.0 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETO01463.1 - 0.027 14.2 0.1 0.15 11.9 0.1 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 ETO01463.1 - 0.028 14.5 0.1 0.081 13.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.1 ETO01463.1 - 0.033 13.2 0.0 0.091 11.8 0.0 1.7 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.9 ETO01463.1 - 0.067 12.9 0.1 0.52 10.0 0.0 2.1 1 1 0 1 1 1 0 Flavivirus DEAD domain NACHT PF05729.7 ETO01466.1 - 0.025 14.2 0.1 0.025 14.2 0.1 1.3 1 1 0 1 1 1 0 NACHT domain HPPK PF01288.15 ETO01466.1 - 0.042 13.5 0.2 0.15 11.7 0.1 1.8 1 1 0 1 1 1 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) DUF4014 PF13198.1 ETO01467.1 - 0.0023 18.2 0.3 0.0036 17.6 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4014) Trypan_glycop_C PF10659.4 ETO01467.1 - 0.24 11.7 3.4 0.86 9.9 2.3 1.9 1 1 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain NAD_binding_5 PF07994.7 ETO01468.1 - 1.2 8.5 4.1 1.9 7.9 2.9 1.4 1 1 0 1 1 1 0 Myo-inositol-1-phosphate synthase LicD PF04991.8 ETO01468.1 - 2.5 8.1 12.1 4 7.4 8.4 1.4 1 1 0 1 1 1 0 LicD family HTH_22 PF13309.1 ETO01468.1 - 3.6 7.4 7.3 0.92 9.3 1.3 2.2 2 0 0 2 2 2 0 HTH domain DUF1690 PF07956.6 ETO01469.1 - 0.0046 16.9 0.5 0.0046 16.9 0.4 1.6 2 0 0 2 2 2 1 Protein of Unknown function (DUF1690) DUF3915 PF13054.1 ETO01469.1 - 1.4 8.9 5.6 3.1 7.7 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3915) Fumble PF03630.9 ETO01472.1 - 0.00011 21.2 0.4 0.00017 20.6 0.3 1.2 1 0 0 1 1 1 1 Fumble Kelch_1 PF01344.20 ETO01472.1 - 0.005 16.3 0.4 0.055 13.0 0.1 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETO01472.1 - 0.0067 16.5 0.3 0.022 14.9 0.1 2.0 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO01472.1 - 0.018 15.1 0.1 0.047 13.8 0.0 1.7 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO01472.1 - 0.021 14.5 0.1 0.096 12.4 0.0 2.0 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO01472.1 - 0.039 13.9 0.7 0.12 12.3 0.5 2.0 1 0 0 1 1 1 0 Kelch motif MACPF PF01823.14 ETO01472.1 - 1 9.0 7.4 0.87 9.2 0.4 2.3 2 1 0 2 2 2 0 MAC/Perforin domain AAA_9 PF12781.2 ETO01473.1 - 0.0083 14.9 0.0 0.0099 14.7 0.0 1.0 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 CENP-F_leu_zip PF10473.4 ETO01474.1 - 0.0013 18.5 17.5 0.0013 18.5 12.1 10.3 3 3 5 10 10 10 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF869 PF05911.6 ETO01474.1 - 0.0016 16.8 30.3 0.0016 16.8 21.0 4.2 2 2 2 4 4 4 3 Plant protein of unknown function (DUF869) GAS PF13851.1 ETO01474.1 - 0.0038 16.4 12.3 0.0038 16.4 8.5 9.4 3 3 4 9 9 9 5 Growth-arrest specific micro-tubule binding DUF1192 PF06698.6 ETO01474.1 - 0.0055 16.4 1.0 0.0055 16.4 0.7 7.8 8 1 0 9 9 9 1 Protein of unknown function (DUF1192) Nup54 PF13874.1 ETO01474.1 - 0.0091 15.6 12.6 0.0091 15.6 8.8 8.9 4 3 4 9 9 9 2 Nucleoporin complex subunit 54 AAA_27 PF13514.1 ETO01474.1 - 0.31 8.6 117.9 0.9 7.1 12.7 4.4 2 1 2 4 4 4 0 AAA domain APG6 PF04111.7 ETO01474.1 - 2.9 6.8 173.0 0.012 14.6 7.2 8.5 3 2 6 9 9 9 0 Autophagy protein Apg6 NAAA-beta PF15508.1 ETO01474.1 - 7 7.0 8.4 3.9 7.9 0.1 4.7 5 1 1 6 6 6 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase ABC_tran PF00005.22 ETO01475.1 - 2.4e-05 24.6 0.2 0.0016 18.7 0.1 2.1 2 0 0 2 2 2 1 ABC transporter Arch_ATPase PF01637.13 ETO01475.1 - 0.0021 17.7 0.2 0.0057 16.3 0.0 1.7 2 0 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 ETO01475.1 - 0.0061 16.7 0.4 0.059 13.5 0.1 2.1 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 ETO01475.1 - 0.0073 15.5 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 ETO01475.1 - 0.01 16.2 0.2 0.034 14.6 0.0 1.9 2 1 1 3 3 3 0 Miro-like protein AAA_5 PF07728.9 ETO01475.1 - 0.016 14.9 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Transp_Tc5_C PF04236.10 ETO01475.1 - 0.021 15.0 0.2 0.045 13.9 0.1 1.5 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain AAA PF00004.24 ETO01475.1 - 0.033 14.3 0.2 0.088 13.0 0.2 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 ETO01475.1 - 0.033 14.5 0.1 0.033 14.5 0.1 2.0 1 1 1 2 2 2 0 AAA domain PduV-EutP PF10662.4 ETO01475.1 - 0.035 13.5 0.2 0.069 12.6 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 ETO01475.1 - 0.05 13.5 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 ETO01475.1 - 0.065 12.8 0.1 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_15 PF13175.1 ETO01475.1 - 0.084 11.9 0.3 0.17 10.9 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain DUF4604 PF15377.1 ETO01476.1 - 0.022 14.9 4.1 0.03 14.5 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) CAML PF14963.1 ETO01476.1 - 0.067 12.5 2.3 0.077 12.3 1.6 1.1 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand BAF1_ABF1 PF04684.8 ETO01476.1 - 0.29 9.9 12.8 0.33 9.7 8.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Serinc PF03348.10 ETO01476.1 - 0.84 8.2 4.0 1 7.9 2.8 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Paramyxo_ncap PF00973.14 ETO01476.1 - 0.9 8.1 11.6 1 7.9 8.0 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Peptidase_S49_N PF08496.5 ETO01476.1 - 0.95 9.2 4.9 1.8 8.3 3.4 1.6 1 1 0 1 1 1 0 Peptidase family S49 N-terminal SID-1_RNA_chan PF13965.1 ETO01476.1 - 1 7.4 5.7 1.1 7.3 4.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Corona_nucleoca PF00937.13 ETO01476.1 - 1.7 7.5 18.5 2.1 7.2 12.8 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF1675 PF07897.6 ETO01476.1 - 2 8.2 11.7 2.3 8.0 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF3533 PF12051.3 ETO01476.1 - 3.8 6.1 7.7 4.2 6.0 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Neur_chan_memb PF02932.11 ETO01476.1 - 8.9 6.1 8.4 11 5.7 5.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hydrolase PF00702.21 ETO01477.1 - 7.1e-10 39.6 0.0 1.2e-09 38.9 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETO01477.1 - 0.00039 20.6 0.0 0.0004 20.6 0.0 1.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase YiaAB PF05360.9 ETO01477.1 - 0.011 15.2 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 yiaA/B two helix domain NACHT PF05729.7 ETO01478.1 - 1.3e-06 28.1 0.0 2.7e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETO01478.1 - 0.00062 19.8 0.0 0.0068 16.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 ETO01478.1 - 0.0026 17.8 0.1 0.035 14.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 ETO01478.1 - 0.0099 14.7 1.8 0.043 12.6 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain AAA_18 PF13238.1 ETO01478.1 - 0.014 15.6 0.0 0.014 15.6 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 ETO01478.1 - 0.032 13.9 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain SMC_N PF02463.14 ETO01478.1 - 0.21 10.7 5.1 0.76 8.9 0.0 2.5 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain BTV_NS2 PF04514.7 ETO01478.1 - 1.4 7.7 11.6 2 7.2 8.1 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 AF1Q PF15017.1 ETO01478.1 - 3.9 7.4 11.9 0.82 9.6 0.9 3.2 3 0 0 3 3 3 0 Drug resistance and apoptosis regulator SET PF00856.23 ETO01479.1 - 0.099 12.9 1.3 0.21 11.8 0.9 1.5 1 0 0 1 1 1 0 SET domain AAA_11 PF13086.1 ETO01479.1 - 0.18 11.3 7.7 0.27 10.7 5.3 1.3 1 0 0 1 1 1 0 AAA domain PEHE PF15275.1 ETO01479.1 - 5.7 7.4 12.7 0.28 11.6 4.8 1.7 2 0 0 2 2 2 0 PEHE domain WD40 PF00400.27 ETO01480.1 - 4.2e-10 39.1 0.7 8.7e-09 34.9 0.1 2.2 2 1 0 2 2 2 1 WD domain, G-beta repeat RPAP2_Rtr1 PF04181.8 ETO01480.1 - 0.046 13.8 0.1 0.063 13.3 0.1 1.1 1 0 0 1 1 1 0 Rtr1/RPAP2 family Kinesin PF00225.18 ETO01481.1 - 6.9e-13 48.0 4.7 5.9e-12 44.9 3.2 2.4 1 1 0 1 1 1 1 Kinesin motor domain PBS_linker_poly PF00427.16 ETO01482.1 - 0.038 13.6 0.0 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide WD40 PF00400.27 ETO01483.1 - 8.5e-14 50.8 2.4 2.4e-10 39.8 0.2 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO01483.1 - 0.00011 20.5 0.1 0.00014 20.1 0.1 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 ComX PF05952.7 ETO01485.1 - 0.059 12.8 0.1 0.17 11.3 0.1 1.8 1 0 0 1 1 1 0 Bacillus competence pheromone ComX DUF3458 PF11940.3 ETO01487.1 - 6.3e-10 38.4 0.1 5.9e-06 25.3 0.0 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF3458) Peptidase_M1 PF01433.15 ETO01488.1 - 9.6e-12 44.6 0.0 1.1e-11 44.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_M1 PF01433.15 ETO01489.1 - 7.8e-06 25.2 0.0 9.6e-06 24.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 DDE_Tnp_IS66 PF03050.9 ETO01489.1 - 0.16 11.1 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Transposase IS66 family zf-TRAF PF02176.13 ETO01490.1 - 4.5e-07 30.1 0.8 4.5e-07 30.1 0.6 2.1 2 0 0 2 2 2 1 TRAF-type zinc finger Sina PF03145.11 ETO01490.1 - 0.03 13.9 0.5 6.5 6.3 0.1 2.7 1 1 1 2 2 2 0 Seven in absentia protein family zf-C3HC4_2 PF13923.1 ETO01490.1 - 0.29 11.1 6.0 0.43 10.6 0.7 3.3 2 2 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Kelch_1 PF01344.20 ETO01491.1 - 0.054 13.0 0.3 7.3 6.2 0.1 2.6 2 0 0 2 2 2 0 Kelch motif Kelch_6 PF13964.1 ETO01491.1 - 0.12 12.5 0.5 4 7.7 0.1 3.2 3 1 1 4 4 4 0 Kelch motif CUE PF02845.11 ETO01493.1 - 0.03 13.8 0.1 0.048 13.1 0.1 1.4 1 0 0 1 1 1 0 CUE domain GlcNAc PF11397.3 ETO01494.1 - 1.3e-05 24.4 0.1 1.3e-05 24.4 0.1 1.8 2 0 0 2 2 2 1 Glycosyltransferase (GlcNAc) CHU_C PF13585.1 ETO01494.1 - 0.2 11.5 2.1 0.46 10.3 1.2 1.8 1 1 1 2 2 2 0 C-terminal domain of CHU protein family CAAP1 PF15335.1 ETO01495.1 - 0.012 15.8 0.7 0.098 12.8 0.1 2.2 2 0 0 2 2 2 0 Caspase activity and apoptosis inhibitor 1 DUF2063 PF09836.4 ETO01495.1 - 0.029 14.3 0.0 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2063) GldM_N PF12081.3 ETO01495.1 - 0.15 11.5 2.3 0.23 10.9 1.4 1.4 1 1 0 1 1 1 0 GldM N-terminal domain RXT2_N PF08595.6 ETO01496.1 - 0.074 12.8 0.1 0.074 12.8 0.1 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF601 PF04642.7 ETO01497.1 - 0.15 11.3 10.7 0.16 11.2 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF601 GEMIN8 PF15348.1 ETO01497.1 - 0.23 11.4 7.0 0.4 10.6 4.0 1.8 1 1 1 2 2 2 0 Gemini of Cajal bodies-associated protein 8 WD40 PF00400.27 ETO01498.1 - 5.9e-33 111.5 16.4 2.7e-12 46.0 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO01498.1 - 1.1e-07 30.3 3.2 0.00032 18.9 0.6 2.5 1 1 1 2 2 2 2 Nucleoporin Nup120/160 RelA_SpoT PF04607.12 ETO01499.1 - 0.0045 16.9 0.7 0.0045 16.9 0.5 2.2 3 0 0 3 3 3 1 Region found in RelA / SpoT proteins DUF3959 PF13105.1 ETO01499.1 - 0.13 11.5 3.7 0.32 10.3 2.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) DUF1308 PF07000.6 ETO01500.1 - 2.7e-31 108.5 0.2 2.7e-31 108.5 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1308) DUF4551 PF15087.1 ETO01500.1 - 3.7 5.8 10.7 0.14 10.4 2.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4551) Dicty_REP PF05086.7 ETO01500.1 - 7 4.2 19.5 0.034 11.9 6.4 1.9 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Menin PF05053.8 ETO01500.1 - 8.9 4.3 10.1 13 3.8 7.0 1.2 1 0 0 1 1 1 0 Menin AAA_18 PF13238.1 ETO01501.1 - 8.8e-07 29.2 1.9 8e-05 22.9 0.0 2.3 1 1 1 2 2 2 1 AAA domain NACHT PF05729.7 ETO01501.1 - 1.7e-05 24.5 0.0 3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 ETO01501.1 - 3.2e-05 24.7 0.3 0.0029 18.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETO01501.1 - 0.00018 21.6 0.0 0.00032 20.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 ETO01501.1 - 0.00036 20.1 0.0 0.00057 19.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 ETO01501.1 - 0.00041 20.2 0.0 0.00071 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain G-alpha PF00503.15 ETO01501.1 - 0.00076 18.2 0.4 0.00086 18.1 0.3 1.2 1 0 0 1 1 1 1 G-protein alpha subunit RNA_helicase PF00910.17 ETO01501.1 - 0.0047 17.0 4.2 0.028 14.5 0.0 2.6 1 1 2 3 3 3 1 RNA helicase PRK PF00485.13 ETO01501.1 - 0.0051 16.4 0.0 0.011 15.2 0.0 1.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_5 PF07728.9 ETO01501.1 - 0.0091 15.7 0.0 0.025 14.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 ETO01501.1 - 0.0096 15.4 0.1 0.026 14.0 0.0 1.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation VirE PF05272.6 ETO01501.1 - 0.017 14.6 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Virulence-associated protein E ATP_bind_2 PF03668.10 ETO01501.1 - 0.019 14.0 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 P-loop ATPase protein family DAP3 PF10236.4 ETO01501.1 - 0.021 13.7 0.1 0.045 12.6 0.1 1.6 1 1 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Torsin PF06309.6 ETO01501.1 - 0.035 13.9 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 Torsin ABC_tran PF00005.22 ETO01501.1 - 0.054 13.8 0.3 0.1 12.9 0.1 1.7 1 1 1 2 2 2 0 ABC transporter Sigma54_activat PF00158.21 ETO01501.1 - 0.069 12.6 0.0 0.099 12.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain T2SE PF00437.15 ETO01501.1 - 0.073 11.9 0.1 0.52 9.1 0.1 2.1 1 1 0 1 1 1 0 Type II/IV secretion system protein DUF258 PF03193.11 ETO01501.1 - 0.091 11.9 0.1 0.15 11.2 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 ETO01501.1 - 0.093 12.7 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.1 ETO01501.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 ETO01501.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 ETO01501.1 - 0.13 12.1 2.3 4.6 7.1 0.0 2.3 1 1 1 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 ETO01501.1 - 0.13 11.7 0.7 3 7.3 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SprA-related PF12118.3 ETO01503.1 - 0.098 11.9 27.9 0.13 11.6 19.4 1.1 1 0 0 1 1 1 0 SprA-related family DUF1510 PF07423.6 ETO01503.1 - 0.12 11.7 28.7 0.21 10.9 19.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Peptidase_C37 PF05416.7 ETO01503.1 - 0.99 7.6 11.7 1 7.5 8.1 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase FLO_LFY PF01698.11 ETO01503.1 - 1.5 7.6 18.1 1.9 7.2 12.6 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Hid1 PF12722.2 ETO01503.1 - 1.6 6.3 25.4 1.9 6.0 17.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MIP-T3 PF10243.4 ETO01503.1 - 1.7 6.9 39.0 2.3 6.5 27.0 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 BTV_NS2 PF04514.7 ETO01503.1 - 1.8 7.3 18.9 2.2 7.0 13.1 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 RR_TM4-6 PF06459.7 ETO01503.1 - 2.6 7.8 22.7 4.6 7.0 15.8 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1675 PF07897.6 ETO01503.1 - 4 7.2 19.2 4.9 6.9 13.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Presenilin PF01080.12 ETO01503.1 - 4.6 5.9 11.3 5.9 5.6 7.8 1.3 1 0 0 1 1 1 0 Presenilin Borrelia_P83 PF05262.6 ETO01503.1 - 4.6 5.3 26.6 4.6 5.3 18.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Herpes_LMP1 PF05297.6 ETO01503.1 - 4.9 5.9 5.3 5.2 5.8 3.7 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Ycf1 PF05758.7 ETO01503.1 - 7 4.2 19.3 8 4.0 13.4 1.1 1 0 0 1 1 1 0 Ycf1 DUF4544 PF15077.1 ETO01503.1 - 8.1 5.8 11.0 12 5.3 7.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) CDC45 PF02724.9 ETO01503.1 - 9.7 4.0 21.9 11 3.9 15.2 1.1 1 0 0 1 1 1 0 CDC45-like protein NACHT PF05729.7 ETO01504.1 - 3e-06 26.9 0.3 3.8e-05 23.3 0.2 2.3 1 1 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO01504.1 - 0.052 13.8 0.2 0.052 13.8 0.2 3.6 2 2 1 3 3 3 0 AAA domain ABC2_membrane PF01061.19 ETO01505.1 - 3e-31 108.2 20.3 7.7e-27 93.8 7.1 2.2 2 0 0 2 2 2 2 ABC-2 type transporter ABC2_membrane_3 PF12698.2 ETO01505.1 - 9.5e-06 24.8 19.6 4e-05 22.8 13.6 1.9 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.2 ETO01505.1 - 1.8 7.3 14.8 3 6.6 9.2 2.1 1 1 1 2 2 2 0 ABC-2 family transporter protein DUF4485 PF14846.1 ETO01507.1 - 0.045 13.4 0.0 0.094 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) DUF2085 PF09858.4 ETO01508.1 - 0.009 16.0 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2085) HTH_40 PF14493.1 ETO01508.1 - 0.079 13.1 0.2 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain WD40 PF00400.27 ETO01509.1 - 1.7e-24 84.7 12.9 1.4e-10 40.5 0.2 4.6 4 1 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO01509.1 - 0.021 13.0 0.2 0.86 7.6 0.0 2.6 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Herpes_heli_pri PF05774.6 ETO01510.1 - 0.058 13.3 3.4 0.38 10.7 0.1 3.0 2 1 1 3 3 3 0 Herpesvirus helicase-primase complex component Peptidase_C14 PF00656.17 ETO01511.1 - 0.0017 18.1 0.1 0.0023 17.6 0.1 1.1 1 0 0 1 1 1 1 Caspase domain DNA_pol3_delta2 PF13177.1 ETO01511.1 - 0.14 11.7 0.6 0.36 10.4 0.4 1.7 1 1 0 1 1 1 0 DNA polymerase III, delta subunit TUG-UBL1 PF11470.3 ETO01512.1 - 0.13 12.2 0.9 0.87 9.5 0.1 2.6 2 1 1 3 3 3 0 GLUT4 regulating protein TUG WD40 PF00400.27 ETO01515.1 - 5e-47 156.1 10.9 4.2e-15 54.9 0.1 4.7 5 0 0 5 5 5 4 WD domain, G-beta repeat PQQ_2 PF13360.1 ETO01515.1 - 3.7e-08 33.1 0.2 0.0012 18.3 0.0 2.2 1 1 1 2 2 2 2 PQQ-like domain BBS2_Mid PF14783.1 ETO01515.1 - 0.00023 20.8 0.1 11 5.8 0.0 4.0 1 1 2 4 4 4 3 Ciliary BBSome complex subunit 2, middle region DUF727 PF05303.7 ETO01515.1 - 0.0006 19.5 0.1 8.8 6.1 0.0 3.6 2 1 2 4 4 4 1 Protein of unknown function (DUF727) Cytochrom_D1 PF02239.11 ETO01515.1 - 0.00095 17.5 0.1 0.27 9.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome D1 heme domain DUF1258 PF06869.7 ETO01515.1 - 0.0015 17.6 0.0 0.84 8.6 0.0 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF1258) Gmad1 PF10647.4 ETO01515.1 - 0.0037 16.7 0.0 0.04 13.3 0.0 2.0 1 1 1 2 2 2 2 Lipoprotein LpqB beta-propeller domain WXG100 PF06013.7 ETO01515.1 - 0.0042 17.0 0.0 14 5.8 0.0 3.1 3 0 0 3 3 3 0 Proteins of 100 residues with WXG PD40 PF07676.7 ETO01515.1 - 0.01 15.5 4.5 1.6 8.4 0.1 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 ETO01515.1 - 0.017 14.4 0.3 17 4.8 0.0 4.4 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature DUF3312 PF11768.3 ETO01515.1 - 0.16 10.1 0.0 9.6 4.2 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3312) TPR_12 PF13424.1 ETO01517.1 - 2.2e-05 24.2 0.0 4.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO01517.1 - 0.0019 17.8 0.8 0.0048 16.5 0.2 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO01517.1 - 0.0019 17.9 0.0 0.0061 16.3 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO01517.1 - 0.012 15.2 0.3 0.037 13.6 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 ETO01517.1 - 0.03 13.9 0.0 0.07 12.7 0.0 1.6 1 0 0 1 1 1 0 TPR repeat TPR_10 PF13374.1 ETO01517.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Prothymosin PF03247.9 ETO01518.1 - 0.0068 16.5 19.2 0.051 13.7 5.3 2.2 2 0 0 2 2 2 2 Prothymosin/parathymosin family BTV_NS2 PF04514.7 ETO01518.1 - 0.049 12.5 17.2 0.062 12.1 11.9 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Imm7 PF15588.1 ETO01518.1 - 0.43 10.6 4.2 1.1 9.3 2.2 2.2 2 1 0 2 2 2 0 Immunity protein 7 SGT1 PF07093.6 ETO01518.1 - 2.8 6.1 16.1 3 6.1 11.1 1.0 1 0 0 1 1 1 0 SGT1 protein DUF1754 PF08555.5 ETO01518.1 - 4.7 7.8 16.5 3.6 8.2 0.9 2.3 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) DUF2540 PF10802.3 ETO01519.1 - 0.029 14.0 0.4 0.04 13.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2540) UBACT PF02134.16 ETO01519.1 - 0.056 13.0 0.4 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 Repeat in ubiquitin-activating (UBA) protein UQ_con PF00179.21 ETO01520.1 - 3.8e-07 29.6 0.7 4.6e-07 29.3 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 ETO01520.1 - 0.00021 21.1 0.2 0.00028 20.7 0.1 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 ETO01520.1 - 0.0096 15.6 0.1 0.015 14.9 0.1 1.3 1 0 0 1 1 1 1 UEV domain Prok-E2_B PF14461.1 ETO01520.1 - 0.016 14.9 0.0 0.027 14.1 0.0 1.4 1 1 0 1 1 1 0 Prokaryotic E2 family B IBN_N PF03810.14 ETO01520.1 - 0.13 12.1 0.4 0.21 11.5 0.3 1.3 1 0 0 1 1 1 0 Importin-beta N-terminal domain WD40 PF00400.27 ETO01521.1 - 5e-15 54.7 6.5 5.7e-11 41.8 1.7 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO01521.1 - 0.00019 19.7 0.2 0.00022 19.4 0.1 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 AMP-binding_C_2 PF14535.1 ETO01522.1 - 0.13 12.2 0.1 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain DUF702 PF05142.7 ETO01523.1 - 4.1 7.5 13.8 8.5 6.5 9.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF702) Protoglobin PF11563.3 ETO01524.1 - 0.078 12.6 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Protoglobin PSD4 PF07631.6 ETO01524.1 - 0.15 12.4 1.2 0.44 10.9 0.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1592) Nodulin_late PF07127.6 ETO01525.1 - 0.16 12.1 5.3 0.25 11.4 0.9 2.4 2 0 0 2 2 2 0 Late nodulin protein Dzip-like_N PF13815.1 ETO01526.1 - 0.053 13.3 0.3 0.056 13.2 0.2 1.0 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal WD40 PF00400.27 ETO01527.1 - 1.6e-52 173.6 19.6 6.9e-10 38.4 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO01527.1 - 6.3e-08 31.2 10.1 0.062 11.4 1.3 4.9 2 2 2 4 4 4 4 Nucleoporin Nup120/160 BBS2_N PF14781.1 ETO01527.1 - 0.053 13.1 2.7 0.18 11.3 0.1 3.1 2 2 2 4 4 4 0 Ciliary BBSome complex subunit 2, N-terminal NAD_Gly3P_dh_N PF01210.18 ETO01527.1 - 0.68 9.6 4.8 32 4.2 0.0 4.1 3 1 1 4 4 4 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ABC_tran PF00005.22 ETO01528.1 - 1.4e-12 48.0 0.0 2.4e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 ETO01528.1 - 0.00021 21.3 0.0 0.00025 21.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 ETO01528.1 - 0.00034 20.4 0.3 0.0063 16.4 0.2 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 ETO01528.1 - 0.011 14.9 0.0 0.013 14.7 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain VWA PF00092.23 ETO01529.1 - 0.00068 19.3 0.1 0.0014 18.3 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Helicase_C PF00271.26 ETO01529.1 - 0.0041 16.9 0.2 0.019 14.8 0.1 2.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 ETO01529.1 - 0.043 13.7 0.1 0.17 11.8 0.0 2.0 1 0 0 1 1 1 0 Helicase C-terminal domain PBP1_TM PF14812.1 ETO01530.1 - 2.9 8.2 13.2 0.27 11.5 4.6 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3513 PF12026.3 ETO01531.1 - 2 7.8 11.4 2.2 7.7 7.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) YjgP_YjgQ PF03739.9 ETO01531.1 - 5.2 5.7 6.7 5.4 5.6 4.7 1.0 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Ly49 PF08391.5 ETO01531.1 - 6.7 6.8 10.3 7.4 6.7 7.1 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Kelch_4 PF13418.1 ETO01535.1 - 0.00029 20.5 0.4 0.0029 17.3 0.0 2.7 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO01535.1 - 0.18 11.4 6.0 0.66 9.5 0.2 3.5 4 0 0 4 4 4 0 Kelch motif RLL PF10036.4 ETO01536.1 - 0.079 12.3 0.0 0.084 12.2 0.0 1.1 1 0 0 1 1 1 0 Putative carnitine deficiency-associated protein PIP5K PF01504.13 ETO01537.1 - 6.1e-29 100.8 1.3 9.9e-29 100.1 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase RP-C_C PF11800.3 ETO01537.1 - 0.099 12.3 1.6 0.13 11.9 1.1 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Ribosomal_L6e PF01159.14 ETO01537.1 - 0.15 12.3 5.3 0.28 11.4 2.7 2.0 2 0 0 2 2 2 0 Ribosomal protein L6e CENP-B_dimeris PF09026.5 ETO01537.1 - 1.7 8.9 7.7 2.9 8.1 5.2 1.5 1 1 0 1 1 1 0 Centromere protein B dimerisation domain TPR_12 PF13424.1 ETO01538.1 - 5.2e-24 83.9 1.4 2.6e-13 49.6 0.1 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO01538.1 - 3.8e-11 42.4 8.1 2e-06 27.3 0.6 2.1 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETO01538.1 - 5.3e-10 38.4 2.6 4.5e-08 32.3 0.9 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO01538.1 - 1e-07 31.2 0.8 3.5e-07 29.5 0.4 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO01538.1 - 1.7e-07 30.4 0.2 1.1e-06 27.9 0.1 2.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO01538.1 - 5.5e-06 25.9 0.9 5e-05 22.9 0.4 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETO01538.1 - 1.8e-05 24.4 0.2 0.00015 21.6 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO01538.1 - 0.00026 21.0 0.6 0.0013 18.8 0.3 1.9 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETO01538.1 - 0.00049 20.3 1.5 0.0014 18.9 0.5 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_3 PF07720.7 ETO01538.1 - 0.00051 19.7 1.4 0.076 12.8 0.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO01538.1 - 0.0011 18.9 0.3 0.009 16.1 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO01538.1 - 0.0012 19.4 0.0 0.0051 17.4 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO01538.1 - 0.0075 16.8 0.0 0.036 14.7 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF2521 PF10730.4 ETO01538.1 - 0.015 15.0 0.0 0.015 15.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2521) Ubiq-assoc PF09145.5 ETO01538.1 - 0.023 14.5 0.7 7.6 6.4 0.2 2.5 1 1 1 2 2 2 0 Ubiquitin-associated MIT PF04212.13 ETO01538.1 - 0.03 14.1 0.8 0.22 11.4 0.3 2.1 1 1 1 2 2 2 0 MIT (microtubule interacting and transport) domain PPR PF01535.15 ETO01538.1 - 0.14 12.1 0.4 5.4 7.2 0.0 2.9 3 0 0 3 3 3 0 PPR repeat DUF2491 PF10679.4 ETO01540.1 - 0.085 11.8 0.1 0.1 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) SOBP PF15279.1 ETO01541.1 - 8.4 6.6 13.4 11 6.3 9.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein VOMI PF03762.12 ETO01542.1 - 0.089 12.7 2.3 0.11 12.4 1.6 1.1 1 0 0 1 1 1 0 Vitelline membrane outer layer protein I (VOMI) MIR PF02815.14 ETO01542.1 - 0.17 11.3 2.8 0.48 9.9 1.8 1.9 1 1 0 1 1 1 0 MIR domain DUF1635 PF07795.6 ETO01542.1 - 0.4 10.0 4.0 0.31 10.3 2.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1635) TMEM51 PF15345.1 ETO01543.1 - 0.036 13.7 1.4 0.041 13.5 1.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 ATP11 PF06644.6 ETO01543.1 - 2 7.8 6.3 2.4 7.5 4.4 1.0 1 0 0 1 1 1 0 ATP11 protein PRP38_assoc PF12871.2 ETO01543.1 - 4.4 7.9 10.0 8.5 6.9 6.9 1.5 1 1 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term O-FucT PF10250.4 ETO01545.1 - 0.041 12.9 0.1 0.041 12.9 0.1 3.1 3 1 0 3 3 3 0 GDP-fucose protein O-fucosyltransferase DUF1031 PF06275.6 ETO01545.1 - 0.044 13.8 0.2 0.17 11.9 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) Exo_endo_phos PF03372.18 ETO01546.1 - 8e-13 48.8 0.0 3.3e-12 46.8 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PMI_typeI PF01238.16 ETO01547.1 - 3.9e-50 170.8 1.1 9.2e-50 169.6 0.7 1.5 1 1 0 1 1 1 1 Phosphomannose isomerase type I RNA_replicase_B PF03431.8 ETO01548.1 - 0.022 12.9 3.0 0.027 12.7 2.1 1.1 1 0 0 1 1 1 0 RNA replicase, beta-chain HCO3_cotransp PF00955.16 ETO01548.1 - 0.1 11.2 3.4 0.12 11.0 2.3 1.0 1 0 0 1 1 1 0 HCO3- transporter family S-antigen PF05756.6 ETO01548.1 - 0.21 11.5 4.8 0.24 11.3 2.8 1.5 1 1 0 1 1 1 0 S-antigen protein Ax_dynein_light PF10211.4 ETO01548.1 - 0.39 10.5 10.8 0.54 10.0 7.5 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain Tox-MPTase5 PF15641.1 ETO01548.1 - 1.2 9.1 5.5 1.8 8.5 3.3 1.7 1 1 0 1 1 1 0 Metallopeptidase toxin 5 YMF19 PF02326.10 ETO01548.1 - 4.5 7.9 7.5 29 5.3 5.2 2.2 1 1 0 1 1 1 0 Plant ATP synthase F0 YbgS PF13985.1 ETO01548.1 - 4.9 7.0 10.0 2.4 8.0 5.5 1.6 1 1 1 2 2 2 0 YbgS-like protein RNA_pol_Rpb1_5 PF04998.12 ETO01548.1 - 9.5 5.3 10.2 12 5.0 7.0 1.2 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Vfa1 PF08432.5 ETO01549.1 - 0.0034 17.4 2.9 0.0054 16.7 2.0 1.2 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Tom37_C PF11801.3 ETO01549.1 - 0.0049 16.7 0.7 0.0049 16.7 0.5 1.5 2 0 0 2 2 2 1 Tom37 C-terminal domain PARG_cat PF05028.9 ETO01550.1 - 1.6e-14 53.9 0.0 1.8e-14 53.7 0.0 1.0 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) Secretin_N_2 PF07655.8 ETO01550.1 - 0.63 10.4 9.0 0.83 10.0 6.3 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain Ferritin PF00210.19 ETO01552.1 - 0.092 12.5 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Ferritin-like domain FAA_hydrolase PF01557.13 ETO01553.1 - 4.5e-07 29.5 0.0 4.8e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family TAP_C PF03943.8 ETO01553.1 - 2.5 7.5 0.0 2.5 7.5 0.0 3.0 4 0 0 4 4 4 0 TAP C-terminal domain HCaRG PF07258.9 ETO01556.1 - 5.9e-17 61.7 0.1 6.2e-17 61.7 0.0 1.0 1 0 0 1 1 1 1 HCaRG protein OMP_b-brl_3 PF14905.1 ETO01557.1 - 0.046 12.4 21.8 0.052 12.2 15.1 1.0 1 0 0 1 1 1 0 Outer membrane protein beta-barrel family Herpes_UL25 PF01499.11 ETO01558.1 - 0.38 8.9 11.8 0.035 12.4 2.1 2.3 2 0 0 2 2 2 0 Herpesvirus UL25 family Mitofilin PF09731.4 ETO01558.1 - 7.3 5.1 63.7 0.044 12.4 18.0 2.1 2 0 0 2 2 2 0 Mitochondrial inner membrane protein Folate_carrier PF01770.13 ETO01563.1 - 0.28 9.6 4.3 0.35 9.3 3.0 1.1 1 0 0 1 1 1 0 Reduced folate carrier DUF3584 PF12128.3 ETO01567.1 - 1.7e-06 25.7 37.5 2.1e-06 25.4 26.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) RNA_pol_Rpb5_C PF01191.14 ETO01567.1 - 0.0053 16.3 1.3 0.023 14.2 0.0 2.7 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain TPR_MLP1_2 PF07926.7 ETO01567.1 - 0.0074 16.0 10.4 0.0074 16.0 7.2 4.0 2 1 0 3 3 3 1 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 ETO01567.1 - 0.0079 15.4 2.4 0.0079 15.4 1.7 2.5 2 1 1 3 3 3 1 Reovirus sigma C capsid protein IncA PF04156.9 ETO01567.1 - 0.0091 15.6 21.6 0.0091 15.6 15.0 3.7 2 1 2 4 4 4 2 IncA protein TMF_DNA_bd PF12329.3 ETO01567.1 - 0.012 15.3 9.8 0.012 15.3 6.8 5.5 4 2 1 5 5 5 0 TATA element modulatory factor 1 DNA binding Tropomyosin_1 PF12718.2 ETO01567.1 - 0.26 11.1 65.4 2 8.2 19.5 3.1 1 1 1 3 3 3 0 Tropomyosin like Mod_r PF07200.8 ETO01567.1 - 0.32 10.9 51.9 0.029 14.2 12.0 4.1 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein GAS PF13851.1 ETO01567.1 - 3.5 6.7 70.1 0.086 12.0 18.7 3.7 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Transpep_BrtH PF14399.1 ETO01568.1 - 0.0035 16.6 0.1 0.0057 15.9 0.1 1.3 1 0 0 1 1 1 1 NlpC/p60-like transpeptidase AIF_C PF14721.1 ETO01570.1 - 0.27 11.4 6.5 0.34 11.1 4.5 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF1371 PF07115.6 ETO01571.1 - 0.0057 16.7 0.3 0.0073 16.4 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1371) DUF494 PF04361.8 ETO01575.1 - 0.035 13.7 1.0 0.34 10.5 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF494) Pilus_CpaD PF09476.5 ETO01575.1 - 0.059 12.8 0.3 0.079 12.4 0.2 1.2 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) Pox_A_type_inc PF04508.7 ETO01575.1 - 0.12 12.2 1.1 0.24 11.2 0.0 2.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat IncA PF04156.9 ETO01575.1 - 0.52 9.8 4.4 0.74 9.3 3.1 1.2 1 0 0 1 1 1 0 IncA protein Apis_Csd PF11671.3 ETO01575.1 - 0.95 9.2 8.0 0.049 13.4 0.5 2.0 2 0 0 2 2 2 0 Complementary sex determiner protein Macoilin PF09726.4 ETO01575.1 - 2.5 6.2 15.3 3 6.0 10.6 1.2 1 0 0 1 1 1 0 Transmembrane protein Utp14 PF04615.8 ETO01575.1 - 3.3 5.7 27.5 4.2 5.4 19.1 1.0 1 0 0 1 1 1 0 Utp14 protein Peptidase_S64 PF08192.6 ETO01575.1 - 9.8 4.3 16.1 12 4.0 11.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 CRAL_TRIO PF00650.15 ETO01576.1 - 2.5e-22 79.0 0.3 3e-22 78.8 0.2 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 ETO01576.1 - 0.00033 20.5 0.5 0.00042 20.2 0.4 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain PDR_CDR PF06422.7 ETO01576.1 - 0.085 12.5 0.3 0.18 11.4 0.2 1.5 1 0 0 1 1 1 0 CDR ABC transporter Metaviral_G PF09595.5 ETO01577.1 - 0.0032 17.1 0.3 0.0047 16.5 0.2 1.2 1 0 0 1 1 1 1 Metaviral_G glycoprotein Y2_Tnp PF04986.8 ETO01577.1 - 0.013 15.2 0.2 0.93 9.2 0.0 2.2 2 0 0 2 2 2 0 Putative transposase Aldo_ket_red PF00248.16 ETO01578.1 - 2.2e-53 180.9 0.0 2.7e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RRM_6 PF14259.1 ETO01579.1 - 0.00086 19.2 0.0 0.056 13.4 0.0 2.9 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Peptidase_M2 PF01401.13 ETO01579.1 - 0.017 13.3 0.1 0.024 12.8 0.1 1.1 1 0 0 1 1 1 0 Angiotensin-converting enzyme La PF05383.12 ETO01580.1 - 5.2e-09 35.7 0.6 5.2e-09 35.7 0.4 2.3 2 1 1 3 3 3 1 La domain RasGAP_C PF03836.10 ETO01582.1 - 0.0038 16.9 3.3 0.0049 16.5 2.3 1.1 1 0 0 1 1 1 1 RasGAP C-terminus XPC-binding PF09280.6 ETO01582.1 - 0.075 12.5 0.3 0.32 10.4 0.0 1.9 2 0 0 2 2 2 0 XPC-binding domain Snapin_Pallidin PF14712.1 ETO01582.1 - 0.092 13.0 0.9 0.14 12.5 0.6 1.2 1 0 0 1 1 1 0 Snapin/Pallidin RNA_pol_3_Rpc31 PF11705.3 ETO01582.1 - 1.4 8.7 6.7 1.8 8.4 4.6 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 WD40 PF00400.27 ETO01584.1 - 2.6e-26 90.4 5.3 9.3e-11 41.1 0.1 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO01584.1 - 8.7e-07 27.4 2.6 0.037 12.1 0.1 2.9 1 1 2 3 3 3 3 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO01584.1 - 0.024 14.3 0.2 1.5 8.5 0.1 2.6 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 ETO01584.1 - 0.026 13.2 1.8 3.4 6.3 0.3 2.4 1 1 1 2 2 2 0 Nup133 N terminal like HAD PF12710.2 ETO01584.1 - 0.1 12.7 0.2 5.9 7.0 0.0 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Ribosomal_S8e PF01201.17 ETO01585.1 - 4.4e-31 107.7 0.0 8.3e-31 106.8 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S8e PUB PF09409.5 ETO01588.1 - 2.1e-05 24.1 1.0 0.00012 21.7 0.7 2.1 1 1 0 1 1 1 1 PUB domain Actin PF00022.14 ETO01589.1 - 2.6e-16 59.0 0.2 5.8e-16 57.8 0.1 1.6 1 1 0 1 1 1 1 Actin DUF3487 PF11990.3 ETO01590.1 - 1.7 8.0 7.1 1.1 8.7 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3487) DUF3488 PF11992.3 ETO01590.1 - 6.2 5.3 10.7 0.31 9.6 3.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) ATHILA PF03078.10 ETO01591.1 - 0.051 12.1 2.3 0.057 11.9 1.6 1.1 1 0 0 1 1 1 0 ATHILA ORF-1 family DUF4278 PF14105.1 ETO01592.1 - 0.084 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4278) DUF106 PF01956.11 ETO01593.1 - 0.75 9.3 3.4 1.4 8.4 2.4 1.5 1 1 0 1 1 1 0 Integral membrane protein DUF106 DUF1644 PF07800.7 ETO01594.1 - 0.18 11.6 8.2 3.9 7.2 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) TPR_11 PF13414.1 ETO01596.1 - 6.3e-06 25.7 4.7 6.3e-06 25.7 3.2 1.9 2 1 0 2 2 2 1 TPR repeat TPR_16 PF13432.1 ETO01596.1 - 0.0039 17.8 0.1 0.0086 16.7 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Reo_sigmaC PF04582.7 ETO01596.1 - 0.004 16.3 1.1 0.0052 16.0 0.8 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein TPR_2 PF07719.12 ETO01596.1 - 0.022 14.6 14.0 0.13 12.1 0.6 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat MT PF12777.2 ETO01596.1 - 0.026 13.2 2.2 0.036 12.8 1.5 1.2 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor TPR_12 PF13424.1 ETO01596.1 - 0.032 14.1 4.4 0.032 14.1 3.0 3.4 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETO01596.1 - 0.079 12.7 1.4 0.079 12.7 0.9 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat DUF3150 PF11348.3 ETO01596.1 - 0.08 12.0 9.3 0.16 11.0 2.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3150) TPR_1 PF00515.23 ETO01596.1 - 0.14 11.8 9.9 0.97 9.1 1.4 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETO01596.1 - 0.17 11.7 2.0 12 6.0 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Hydrolase_6 PF13344.1 ETO01596.1 - 0.38 10.6 2.8 0.52 10.2 0.9 1.9 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase YlqD PF11068.3 ETO01596.1 - 1.6 8.7 24.5 0.11 12.4 8.0 2.4 1 1 1 2 2 2 0 YlqD protein Ax_dynein_light PF10211.4 ETO01596.1 - 2.4 7.9 19.3 0.23 11.2 9.5 1.9 1 1 1 2 2 2 0 Axonemal dynein light chain ARD PF03079.9 ETO01596.1 - 2.7 7.9 9.5 2.9 7.8 6.1 1.4 1 1 0 1 1 1 0 ARD/ARD' family Phage_GPO PF05929.6 ETO01596.1 - 2.7 7.1 13.6 3.5 6.7 9.4 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase PhoQ_Sensor PF08918.5 ETO01596.1 - 3.4 7.1 6.6 0.57 9.6 1.0 2.0 1 1 1 2 2 2 0 PhoQ Sensor PNPase PF03726.9 ETO01596.1 - 6.5 7.1 8.2 5.9 7.2 1.7 2.4 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain DUF87 PF01935.12 ETO01596.1 - 7.5 6.2 10.8 19 4.9 6.8 1.8 1 1 1 2 2 2 0 Domain of unknown function DUF87 DUF4407 PF14362.1 ETO01596.1 - 8.1 5.3 11.8 12 4.7 8.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CDC45 PF02724.9 ETO01597.1 - 0.013 13.6 6.5 0.014 13.4 4.5 1.1 1 0 0 1 1 1 0 CDC45-like protein FimP PF09766.4 ETO01597.1 - 0.026 13.5 3.7 0.032 13.3 2.6 1.1 1 0 0 1 1 1 0 Fms-interacting protein YL1 PF05764.8 ETO01597.1 - 0.057 13.0 12.9 0.075 12.6 8.9 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Tom37_C PF11801.3 ETO01597.1 - 0.16 11.8 6.7 0.22 11.3 4.6 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain NPR3 PF03666.8 ETO01597.1 - 0.91 7.9 4.6 1 7.8 3.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 eIF-3c_N PF05470.7 ETO01597.1 - 0.98 7.4 12.2 1.2 7.1 8.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SDA1 PF05285.7 ETO01597.1 - 2.6 7.2 18.4 3.4 6.8 12.7 1.1 1 0 0 1 1 1 0 SDA1 Spt5_N PF11942.3 ETO01597.1 - 2.7 8.6 17.6 4.1 8.0 12.2 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Nop14 PF04147.7 ETO01597.1 - 3 5.6 18.0 3.8 5.3 12.5 1.0 1 0 0 1 1 1 0 Nop14-like family Pox_RNA_Pol_19 PF05320.7 ETO01597.1 - 4.5 6.9 10.8 6.7 6.4 7.5 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Rota_VP2 PF05087.7 ETO01597.1 - 5.3 4.8 8.1 6.9 4.4 5.6 1.2 1 0 0 1 1 1 0 Rotavirus VP2 protein SAPS PF04499.10 ETO01597.1 - 5.7 5.4 9.0 7.3 5.0 6.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TRAP_alpha PF03896.11 ETO01597.1 - 7 5.5 10.8 9.2 5.1 7.5 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit HSP90 PF00183.13 ETO01597.1 - 7.3 4.8 15.8 9.9 4.4 11.0 1.1 1 0 0 1 1 1 0 Hsp90 protein XAP5 PF04921.9 ETO01597.1 - 8.1 5.9 13.1 11 5.4 9.1 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator Sec62 PF03839.11 ETO01597.1 - 8.7 5.6 9.2 11 5.3 6.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Cwf_Cwc_15 PF04889.7 ETO01598.1 - 0.002 17.8 12.5 0.0024 17.6 8.7 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF1510 PF07423.6 ETO01598.1 - 0.0086 15.4 13.1 0.012 15.0 9.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) PPP4R2 PF09184.6 ETO01598.1 - 0.0088 15.6 12.9 0.0097 15.4 9.0 1.2 1 0 0 1 1 1 1 PPP4R2 Hid1 PF12722.2 ETO01598.1 - 0.033 11.9 12.5 0.037 11.7 8.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nop14 PF04147.7 ETO01598.1 - 0.037 11.9 14.8 0.04 11.8 10.2 1.1 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.5 ETO01598.1 - 0.061 13.3 11.9 0.099 12.6 8.3 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Cnd1_N PF12922.2 ETO01598.1 - 0.13 11.8 5.2 1.2 8.7 0.6 2.1 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term SDA1 PF05285.7 ETO01598.1 - 0.14 11.4 17.3 0.18 11.0 12.0 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 ETO01598.1 - 0.16 9.9 15.5 0.19 9.7 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein FLO_LFY PF01698.11 ETO01598.1 - 0.16 10.7 7.3 0.18 10.6 5.1 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Presenilin PF01080.12 ETO01598.1 - 0.25 10.1 4.9 0.3 9.8 3.4 1.1 1 0 0 1 1 1 0 Presenilin Pox_Ag35 PF03286.9 ETO01598.1 - 0.35 10.3 13.1 0.5 9.8 9.1 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NARP1 PF12569.3 ETO01598.1 - 0.44 9.2 7.7 0.53 8.9 5.4 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 NPR3 PF03666.8 ETO01598.1 - 0.52 8.7 14.1 0.77 8.2 9.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.7 ETO01598.1 - 0.69 9.7 7.3 1 9.1 5.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Raftlin PF15250.1 ETO01598.1 - 0.7 8.3 6.0 0.76 8.2 4.2 1.2 1 0 0 1 1 1 0 Raftlin GPCR_chapero_1 PF11904.3 ETO01598.1 - 0.76 8.8 8.2 0.9 8.6 5.7 1.1 1 0 0 1 1 1 0 GPCR-chaperone Suf PF05843.9 ETO01598.1 - 0.83 9.3 5.2 0.97 9.1 3.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) NOA36 PF06524.7 ETO01598.1 - 1 8.5 11.3 1.2 8.2 7.8 1.2 1 0 0 1 1 1 0 NOA36 protein Tom37_C PF11801.3 ETO01598.1 - 1.1 9.1 6.6 1.7 8.4 4.6 1.4 1 0 0 1 1 1 0 Tom37 C-terminal domain Neur_chan_memb PF02932.11 ETO01598.1 - 1.2 8.9 5.1 1.3 8.8 3.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.10 ETO01598.1 - 1.2 7.6 11.3 1.7 7.2 7.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Paramyxo_ncap PF00973.14 ETO01598.1 - 1.3 7.6 7.1 1.4 7.5 5.0 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Daxx PF03344.10 ETO01598.1 - 1.8 6.9 17.1 2.3 6.6 11.8 1.1 1 0 0 1 1 1 0 Daxx Family Cryptochrome_C PF12546.3 ETO01598.1 - 1.9 9.2 10.8 0.28 11.8 4.0 2.1 3 0 0 3 3 2 0 Blue/Ultraviolet sensing protein C terminal DUF2201_N PF13203.1 ETO01598.1 - 2.1 7.4 10.5 3.1 6.8 7.3 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Sporozoite_P67 PF05642.6 ETO01598.1 - 2.6 5.8 15.7 3.4 5.3 10.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Zip PF02535.17 ETO01598.1 - 3.4 6.5 4.5 4.1 6.3 3.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_C14 PF00656.17 ETO01599.1 - 2.4e-06 27.4 0.4 1.6e-05 24.7 0.3 1.8 1 1 0 1 1 1 1 Caspase domain TPR_12 PF13424.1 ETO01600.1 - 1.1e-37 127.7 6.7 1.6e-18 66.3 0.4 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO01600.1 - 2.9e-26 89.9 22.3 5.1e-09 35.3 2.7 5.4 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETO01600.1 - 5.8e-22 75.7 12.9 4.2e-07 29.3 0.7 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO01600.1 - 2.1e-21 75.3 12.4 1.8e-06 27.5 1.1 3.5 2 2 1 3 3 3 3 TPR repeat TPR_8 PF13181.1 ETO01600.1 - 3e-20 70.4 23.7 2.2e-07 30.1 2.7 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO01600.1 - 1.1e-17 62.3 2.2 9.4e-05 21.9 0.0 4.8 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO01600.1 - 5.9e-17 60.9 0.0 2.6e-06 27.1 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO01600.1 - 1.5e-06 28.2 8.2 0.016 15.5 0.2 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO01600.1 - 2.3e-05 24.2 13.3 0.39 11.0 2.0 5.0 4 1 0 4 4 4 2 Tetratricopeptide repeat Peptidase_C14 PF00656.17 ETO01600.1 - 2.4e-05 24.1 0.6 6.3e-05 22.7 0.4 1.6 1 0 0 1 1 1 1 Caspase domain TPR_16 PF13432.1 ETO01600.1 - 0.00014 22.4 0.1 0.027 15.1 0.1 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO01600.1 - 0.00015 22.0 0.0 8.7 7.2 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO01600.1 - 0.00029 20.8 11.9 0.00077 19.5 4.9 3.3 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO01600.1 - 0.0034 17.6 0.7 0.72 10.2 0.3 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat MIT PF04212.13 ETO01600.1 - 0.012 15.5 5.8 3.3 7.6 0.3 3.9 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.4 ETO01600.1 - 0.068 12.4 0.1 33 3.8 0.0 3.6 4 0 0 4 4 4 0 SHNi-TPR TPR_3 PF07720.7 ETO01600.1 - 1.2 8.9 14.3 2.7 7.8 1.2 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat PI3_PI4_kinase PF00454.22 ETO01602.1 - 1e-07 31.6 0.0 1.5e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PDR_CDR PF06422.7 ETO01602.1 - 0.031 13.9 1.2 0.052 13.2 0.8 1.3 1 0 0 1 1 1 0 CDR ABC transporter RGM_N PF06535.7 ETO01603.1 - 0.18 11.7 1.7 0.9 9.5 1.2 2.0 1 1 0 1 1 1 0 Repulsive guidance molecule (RGM) N-terminus GPS PF01825.16 ETO01603.1 - 5.5 7.1 7.3 1.2e+02 2.8 0.1 4.0 3 1 0 3 3 3 0 Latrophilin/CL-1-like GPS domain Cor1 PF04803.7 ETO01604.1 - 0.21 11.3 1.9 2 8.2 0.1 2.2 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region zf-RanBP PF00641.13 ETO01605.1 - 7.5e-06 24.9 5.0 7.5e-06 24.9 3.4 1.9 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others UPF0233 PF06781.7 ETO01605.1 - 0.048 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) DZR PF12773.2 ETO01605.1 - 0.51 10.2 7.0 0.96 9.3 4.8 1.4 1 0 0 1 1 1 0 Double zinc ribbon NACHT PF05729.7 ETO01607.1 - 0.044 13.4 0.0 0.044 13.4 0.0 1.1 1 0 0 1 1 1 0 NACHT domain HSP70 PF00012.15 ETO01609.1 - 5.3e-47 160.0 0.5 2.3e-31 108.4 0.5 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 ETO01609.1 - 3.9e-10 38.8 0.6 5.2e-10 38.4 0.4 1.3 1 1 0 1 1 1 1 MreB/Mbl protein MRG PF05712.8 ETO01609.1 - 0.04 12.8 0.1 0.08 11.8 0.1 1.5 1 1 0 1 1 1 0 MRG MMR_HSR1 PF01926.18 ETO01610.1 - 3.9e-11 42.9 0.1 8.9e-11 41.7 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 ETO01610.1 - 1e-05 24.7 0.2 1e-05 24.7 0.2 3.1 3 0 0 3 3 3 1 Protein of unknown function, DUF258 Miro PF08477.8 ETO01610.1 - 2.5e-05 24.7 0.2 6.4e-05 23.4 0.1 1.8 1 0 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 ETO01610.1 - 5e-05 23.6 0.6 0.00026 21.3 0.1 2.1 2 0 0 2 2 2 1 ABC transporter AIG1 PF04548.11 ETO01610.1 - 0.00042 19.4 0.2 0.0008 18.5 0.2 1.5 1 0 0 1 1 1 1 AIG1 family FeoB_N PF02421.13 ETO01610.1 - 0.0012 18.1 0.2 0.002 17.4 0.2 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF815 PF05673.8 ETO01610.1 - 0.0029 16.5 0.0 0.0049 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.1 ETO01610.1 - 0.0034 16.8 0.1 0.0089 15.5 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Dynamin_N PF00350.18 ETO01610.1 - 0.0036 17.1 1.2 0.042 13.6 0.3 2.3 1 1 1 2 2 2 1 Dynamin family Arch_ATPase PF01637.13 ETO01610.1 - 0.0069 16.1 0.3 0.013 15.2 0.0 1.5 2 0 0 2 2 2 1 Archaeal ATPase AAA_21 PF13304.1 ETO01610.1 - 0.052 13.4 0.1 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 ETO01610.1 - 0.066 12.2 0.1 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.1 ETO01610.1 - 0.074 13.1 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 ETO01610.1 - 0.11 11.9 0.5 0.36 10.3 0.4 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation UPF0079 PF02367.12 ETO01610.1 - 0.12 12.0 0.1 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 ETO01610.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 ETO01610.1 - 0.17 12.2 1.9 0.65 10.3 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 ETO01610.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 ETO01610.1 - 1.8 8.8 8.6 7.7 6.7 6.0 2.1 1 1 0 1 1 1 0 AAA domain RRM_6 PF14259.1 ETO01611.1 - 1.2e-20 73.2 0.0 8.6e-10 38.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO01611.1 - 2.6e-15 55.8 0.0 9.2e-07 28.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO01611.1 - 4.8e-05 23.1 0.0 0.01 15.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RED_N PF07808.8 ETO01614.1 - 0.022 13.9 6.7 0.037 13.2 4.7 1.4 1 1 0 1 1 1 0 RED-like protein N-terminal region ABC_tran_2 PF12848.2 ETO01614.1 - 0.081 12.7 2.6 0.088 12.6 1.8 1.3 1 0 0 1 1 1 0 ABC transporter FKBP_N PF01346.13 ETO01614.1 - 0.27 11.3 6.2 0.29 11.1 4.3 1.1 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Rep_2 PF01719.12 ETO01614.1 - 0.31 10.5 3.8 0.34 10.4 2.7 1.0 1 0 0 1 1 1 0 Plasmid replication protein Kelch_2 PF07646.10 ETO01615.1 - 6.8e-07 28.8 0.1 0.002 17.8 0.2 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.1 ETO01615.1 - 4.2e-06 26.7 0.5 0.0033 17.5 0.3 2.5 1 1 1 2 2 2 2 Kelch motif Kelch_1 PF01344.20 ETO01615.1 - 8e-06 25.3 1.8 0.001 18.5 0.5 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 ETO01615.1 - 9.1e-06 25.3 0.1 0.13 12.0 0.0 2.5 2 1 0 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO01615.1 - 0.00019 21.4 0.0 0.006 16.7 0.0 2.7 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO01615.1 - 0.0012 18.7 0.2 0.17 11.8 0.3 2.2 2 0 0 2 2 2 1 Kelch motif Glyoxal_oxid_N PF07250.6 ETO01615.1 - 0.055 12.5 0.0 0.062 12.3 0.0 1.1 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus Peptidase_M48 PF01435.13 ETO01616.1 - 7.9e-27 94.2 0.6 2.3e-26 92.7 0.4 1.8 1 0 0 1 1 1 1 Peptidase family M48 Thioredoxin_4 PF13462.1 ETO01616.1 - 3.9e-23 82.2 0.0 3.9e-23 82.2 0.0 3.1 4 0 0 4 4 3 1 Thioredoxin DSBA PF01323.15 ETO01616.1 - 6.8e-20 71.4 0.0 1.2e-18 67.3 0.0 2.6 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 ETO01616.1 - 1e-08 35.3 1.1 3.6e-08 33.6 0.0 2.6 2 1 0 2 2 2 1 Thioredoxin-like domain TPR_19 PF14559.1 ETO01616.1 - 1.3e-08 35.0 1.7 0.0089 16.3 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO01616.1 - 3e-07 30.9 0.0 9.9e-07 29.2 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO01616.1 - 1.8e-05 24.2 3.7 0.0014 18.2 0.1 3.6 2 1 2 4 4 3 1 TPR repeat Fis1_TPR_C PF14853.1 ETO01616.1 - 0.00014 21.6 2.3 0.00042 20.1 0.1 2.8 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat Apc3 PF12895.2 ETO01616.1 - 0.00016 21.6 2.3 0.01 15.9 0.1 2.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 ETO01616.1 - 0.00038 20.1 1.1 0.1 12.5 0.0 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat DUF2201_N PF13203.1 ETO01616.1 - 0.00058 19.1 0.7 0.0009 18.4 0.0 1.6 2 0 0 2 2 1 1 Putative metallopeptidase domain Thioredoxin PF00085.15 ETO01616.1 - 0.0035 16.9 0.3 0.051 13.2 0.1 3.2 2 1 1 3 3 3 1 Thioredoxin TPR_17 PF13431.1 ETO01616.1 - 0.0035 17.4 0.8 7.2 7.0 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO01616.1 - 0.027 15.0 0.0 6.2 7.7 0.0 3.4 2 1 1 3 3 2 0 Tetratricopeptide repeat Gly-zipper_OmpA PF13436.1 ETO01616.1 - 0.18 11.4 3.6 0.36 10.4 1.6 2.0 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Thioredoxin_3 PF13192.1 ETO01616.1 - 0.26 11.1 7.0 7.1 6.5 0.0 3.9 3 1 1 4 4 4 0 Thioredoxin domain GAT PF03127.9 ETO01616.1 - 1.2 9.1 7.2 0.31 11.0 1.1 2.8 3 0 0 3 3 2 0 GAT domain Glypican PF01153.14 ETO01617.1 - 0.52 8.8 3.4 0.63 8.5 2.3 1.1 1 0 0 1 1 1 0 Glypican CobT PF06213.7 ETO01617.1 - 1.1 8.3 3.5 1.8 7.6 2.4 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1453 PF07301.6 ETO01618.1 - 0.03 14.2 0.0 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1453) ETRAMP PF09716.5 ETO01618.1 - 0.031 14.2 0.5 0.042 13.7 0.4 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) BAR_2 PF10455.4 ETO01618.1 - 0.031 13.1 0.2 0.034 13.0 0.2 1.0 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Potyvirid-P3 PF13608.1 ETO01618.1 - 0.044 12.8 0.1 0.048 12.7 0.0 1.0 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein DUF819 PF05684.7 ETO01618.1 - 0.065 12.0 0.0 0.071 11.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF819) CRA PF06589.6 ETO01618.1 - 0.077 12.3 0.3 0.092 12.0 0.2 1.1 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Nucleoside_tran PF01733.13 ETO01618.1 - 0.1 11.7 0.1 0.1 11.7 0.0 1.0 1 0 0 1 1 1 0 Nucleoside transporter zf-C3HC4_2 PF13923.1 ETO01619.1 - 0.0086 16.0 3.6 0.13 12.2 1.0 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Toxin_1 PF00087.16 ETO01619.1 - 2.7 8.4 7.5 0.72 10.2 0.3 2.7 2 1 1 3 3 3 0 Snake toxin zf-C3HC4_2 PF13923.1 ETO01620.1 - 0.024 14.6 4.7 0.28 11.2 3.2 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Alpha_kinase PF02816.13 ETO01620.1 - 0.042 13.5 1.1 0.053 13.1 0.7 1.1 1 0 0 1 1 1 0 Alpha-kinase family KBP_C PF12309.3 ETO01622.1 - 0.0032 16.4 0.6 0.007 15.3 0.1 1.5 1 1 0 1 1 1 1 KIF-1 binding protein C terminal FadR_C PF07840.7 ETO01622.1 - 0.025 14.2 0.6 0.05 13.2 0.4 1.6 1 1 0 1 1 1 0 FadR C-terminal domain Phage_glycop_gL PF11108.3 ETO01622.1 - 0.13 12.2 2.2 3.7 7.5 0.1 2.9 2 1 1 3 3 3 0 Viral glycoprotein L TPR_12 PF13424.1 ETO01623.1 - 4.5e-13 48.9 0.5 2.5e-12 46.5 0.1 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO01623.1 - 5.6e-09 35.2 8.3 1e-05 24.9 1.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO01623.1 - 5.6e-08 32.3 4.0 1.5e-07 30.9 1.0 2.5 2 1 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 ETO01623.1 - 7.6e-08 31.7 4.5 0.0016 18.2 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO01623.1 - 7e-07 28.5 0.2 0.015 15.0 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO01623.1 - 6.7e-06 25.5 8.5 0.02 14.6 0.7 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO01623.1 - 1.2e-05 25.0 0.0 0.064 13.2 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO01623.1 - 0.00055 20.0 4.9 0.0011 19.0 1.0 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF2225 PF09986.4 ETO01623.1 - 0.0046 16.4 4.5 0.0085 15.5 1.6 1.9 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.13 ETO01623.1 - 0.0053 16.6 2.2 0.56 10.1 0.1 3.1 2 1 1 3 3 3 1 MIT (microtubule interacting and transport) domain P22_AR_C PF10548.4 ETO01623.1 - 0.021 14.6 0.2 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 P22AR C-terminal domain SelB-wing_3 PF09107.6 ETO01623.1 - 0.12 11.7 0.1 1.7 8.0 0.0 2.4 1 1 1 2 2 2 0 Elongation factor SelB, winged helix TPR_14 PF13428.1 ETO01623.1 - 0.14 12.8 0.0 19 6.2 0.0 2.6 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 ETO01623.1 - 0.66 10.3 5.2 0.8 10.0 0.3 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.7 ETO01623.1 - 2.4 8.0 9.0 3.2 7.6 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4_2 PF13923.1 ETO01624.1 - 0.0055 16.6 1.7 0.064 13.2 1.2 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO01624.1 - 0.039 13.7 1.1 0.14 11.9 0.7 1.9 1 1 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.1 ETO01624.1 - 1.5 8.4 5.0 5.5 6.6 0.2 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.20 ETO01624.1 - 1.8 8.2 5.4 15 5.3 0.1 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 ETO01624.1 - 2 8.3 5.3 0.63 9.9 1.2 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING CAF-1_p150 PF11600.3 ETO01625.1 - 0.011 15.1 8.9 0.013 14.8 6.2 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal MMR_HSR1 PF01926.18 ETO01626.1 - 9.3e-06 25.5 1.5 2.4e-05 24.2 0.1 2.6 2 2 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 ETO01626.1 - 3.6e-05 23.0 1.9 0.00017 20.8 0.2 2.7 2 1 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 ETO01626.1 - 0.0016 18.7 1.7 0.0026 18.0 0.0 2.2 2 1 0 2 2 2 1 ABC transporter Dynamin_N PF00350.18 ETO01626.1 - 0.011 15.5 3.2 1.1 9.0 0.0 3.2 2 1 1 3 3 3 0 Dynamin family AAA_22 PF13401.1 ETO01626.1 - 0.013 15.6 4.4 0.2 11.7 0.0 3.5 3 1 0 3 3 3 0 AAA domain AAA_29 PF13555.1 ETO01626.1 - 0.013 15.0 0.1 0.026 14.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 ETO01626.1 - 0.016 14.1 0.0 0.041 12.7 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein Baculo_RING PF05883.6 ETO01626.1 - 0.025 14.4 2.1 0.66 9.8 0.0 3.2 2 1 0 2 2 2 0 Baculovirus U-box/Ring-like domain AAA_16 PF13191.1 ETO01626.1 - 0.026 14.5 1.3 0.61 10.0 0.0 3.1 2 1 1 3 3 3 0 AAA ATPase domain AAA_23 PF13476.1 ETO01626.1 - 0.027 14.7 0.1 0.027 14.7 0.0 3.8 2 1 0 2 2 1 0 AAA domain Miro PF08477.8 ETO01626.1 - 0.029 14.8 0.0 0.15 12.6 0.0 2.3 1 0 0 1 1 1 0 Miro-like protein AAA_28 PF13521.1 ETO01626.1 - 0.034 14.0 0.1 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2365 PF10157.4 ETO01626.1 - 0.038 13.8 1.5 0.17 11.7 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2365) PhoH PF02562.11 ETO01626.1 - 0.056 12.6 0.1 0.29 10.3 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.1 ETO01626.1 - 0.077 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Exo_endo_phos_2 PF14529.1 ETO01627.1 - 5.9e-18 64.5 2.0 1.1e-17 63.7 1.4 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Disaggr_assoc PF08480.5 ETO01628.1 - 0.026 13.9 0.0 0.032 13.6 0.0 1.1 1 0 0 1 1 1 0 Disaggregatase related DNA_topoisoIV PF00521.15 ETO01628.1 - 0.14 11.0 0.7 0.15 10.8 0.5 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A ATP_synth_reg PF14960.1 ETO01629.1 - 0.013 14.6 1.6 0.42 9.8 0.3 2.4 2 0 0 2 2 2 0 ATP synthase regulation BOFC_N PF08977.5 ETO01629.1 - 0.023 14.5 1.3 2.1 8.2 0.1 2.4 2 0 0 2 2 2 0 Bypass of Forespore C, N terminal DUF4130 PF13566.1 ETO01629.1 - 0.029 13.9 4.6 0.75 9.3 0.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4130 DUF3292 PF11696.3 ETO01629.1 - 0.048 11.5 0.6 0.053 11.4 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) RSV_NS2 PF03113.9 ETO01632.1 - 0.068 13.1 0.3 0.08 12.8 0.2 1.2 1 0 0 1 1 1 0 Respiratory synctial virus non-structural protein NS2 RRM_1 PF00076.17 ETO01633.1 - 8.7e-09 34.8 0.0 0.00028 20.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO01633.1 - 5.8e-06 26.1 0.0 0.032 14.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETO01633.1 - 5.4e-05 22.8 0.1 0.23 11.2 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DUF996 PF06195.8 ETO01633.1 - 0.13 12.2 0.2 0.18 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF996) LAGLIDADG_WhiA PF14527.1 ETO01634.1 - 0.053 13.3 5.1 1.4 8.7 0.1 3.3 2 1 1 3 3 3 0 WhiA LAGLIDADG-like domain DUF2203 PF09969.4 ETO01634.1 - 1.9 8.7 7.5 0.62 10.2 0.2 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Ndc80_HEC PF03801.8 ETO01639.1 - 0.095 12.1 4.1 2.4 7.5 0.2 2.2 1 1 0 2 2 2 0 HEC/Ndc80p family GRIM-19 PF06212.7 ETO01639.1 - 0.1 12.3 0.1 0.64 9.7 0.0 1.9 2 0 0 2 2 2 0 GRIM-19 protein Peptidase_C14 PF00656.17 ETO01641.1 - 1e-14 54.8 1.5 1e-14 54.8 0.1 1.6 2 0 0 2 2 2 1 Caspase domain ATC_hydrolase PF14196.1 ETO01641.1 - 0.75 10.1 5.8 7.7 6.9 1.8 2.4 2 0 0 2 2 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase TPR_12 PF13424.1 ETO01642.1 - 1.2e-38 130.9 3.8 3.2e-17 62.2 0.1 4.0 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO01642.1 - 2e-16 59.3 7.8 8.8e-07 28.4 0.0 4.3 2 2 0 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETO01642.1 - 5.3e-16 57.4 18.1 3.6e-08 32.6 1.3 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO01642.1 - 2.8e-13 48.5 1.0 0.003 17.2 0.0 4.7 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO01642.1 - 9.9e-13 46.9 10.5 1.2e-05 24.8 0.6 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO01642.1 - 1.5e-12 46.3 13.3 3.6e-05 23.2 0.3 5.0 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO01642.1 - 1.4e-10 40.7 0.0 2.6e-05 24.0 0.0 4.1 4 1 0 4 4 4 2 Tetratricopeptide repeat RPN7 PF10602.4 ETO01642.1 - 0.00016 21.0 1.8 0.00024 20.5 0.1 2.1 2 1 0 2 2 2 1 26S proteasome subunit RPN7 DUF627 PF04781.7 ETO01642.1 - 0.00068 19.2 0.1 0.0055 16.3 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF627) TPR_14 PF13428.1 ETO01642.1 - 0.00074 19.9 0.0 0.78 10.5 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO01642.1 - 0.0095 16.0 1.5 0.033 14.3 0.4 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETO01642.1 - 0.06 13.8 0.2 22 5.8 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETO01642.1 - 0.062 13.9 0.1 1.6 9.5 0.0 2.8 2 2 2 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 ETO01642.1 - 0.076 12.8 4.1 27 4.7 0.0 4.1 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain DUF3997 PF13162.1 ETO01642.1 - 0.36 10.6 8.6 0.29 10.9 2.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3997) TPR_17 PF13431.1 ETO01642.1 - 0.54 10.5 5.8 14 6.1 0.2 4.5 3 2 1 4 4 4 0 Tetratricopeptide repeat MMR_HSR1 PF01926.18 ETO01643.1 - 1.1e-06 28.6 0.0 2.3e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 ETO01643.1 - 0.00017 20.3 0.1 0.00021 20.1 0.1 1.3 1 0 0 1 1 1 1 G-protein alpha subunit T2SE PF00437.15 ETO01643.1 - 0.00029 19.8 0.0 0.00037 19.4 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 ETO01643.1 - 0.00076 19.3 1.3 0.0015 18.3 0.3 1.9 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Thymidylate_kin PF02223.12 ETO01643.1 - 0.00085 18.7 1.3 0.82 9.0 0.0 2.6 2 0 0 2 2 2 2 Thymidylate kinase AAA_22 PF13401.1 ETO01643.1 - 0.006 16.7 0.0 0.029 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain Gtr1_RagA PF04670.7 ETO01643.1 - 0.0071 15.5 0.0 0.019 14.1 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.13 ETO01643.1 - 0.0072 15.8 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family SRP54 PF00448.17 ETO01643.1 - 0.011 15.1 0.2 0.23 10.8 0.2 2.2 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.22 ETO01643.1 - 0.026 14.8 0.1 0.062 13.6 0.0 1.8 1 1 0 1 1 1 0 ABC transporter AAA_17 PF13207.1 ETO01643.1 - 0.032 15.0 0.2 0.11 13.3 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 ETO01643.1 - 0.04 13.4 0.0 0.089 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arf PF00025.16 ETO01643.1 - 0.046 12.9 0.3 0.17 11.0 0.2 1.9 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA_5 PF07728.9 ETO01643.1 - 0.081 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 ETO01643.1 - 0.088 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 ETO01643.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 ETO01643.1 - 0.12 12.5 0.3 2 8.5 0.2 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DBI_PRT PF02277.12 ETO01643.1 - 0.14 11.2 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 Phosphoribosyltransferase DUF4109 PF13397.1 ETO01644.1 - 0.068 13.5 0.0 0.098 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4109) NACHT PF05729.7 ETO01645.1 - 3.7e-12 46.2 0.1 1.6e-10 40.8 0.0 2.5 1 1 1 2 2 2 1 NACHT domain AAA_16 PF13191.1 ETO01645.1 - 0.00078 19.4 0.0 0.0064 16.5 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 ETO01645.1 - 0.0017 17.2 0.5 0.0027 16.5 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.1 ETO01645.1 - 0.0041 17.2 0.1 0.012 15.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 ETO01645.1 - 0.041 13.1 0.0 0.95 8.6 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.1 ETO01645.1 - 0.056 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain Torsin PF06309.6 ETO01645.1 - 0.07 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_18 PF13238.1 ETO01645.1 - 0.13 12.5 2.9 0.15 12.3 0.4 2.5 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.12 ETO01645.1 - 0.14 11.9 3.2 0.22 11.3 0.1 2.5 2 2 0 2 2 2 0 Domain of unknown function DUF87 Y_phosphatase PF00102.22 ETO01648.1 - 0.053 12.8 3.7 0.22 10.8 0.2 2.1 1 1 1 2 2 2 0 Protein-tyrosine phosphatase WD40 PF00400.27 ETO01650.1 - 1.6e-13 49.9 4.0 3.7e-12 45.6 0.1 3.0 3 1 0 3 3 3 2 WD domain, G-beta repeat Pkinase PF00069.20 ETO01653.1 - 1.5e-45 155.3 0.1 1.7e-45 155.2 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO01653.1 - 5.4e-24 84.6 0.1 6.3e-24 84.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO01653.1 - 3.8e-07 29.3 0.1 5.4e-07 28.8 0.1 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETO01653.1 - 0.00047 19.2 0.0 0.00062 18.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 ETO01653.1 - 0.0056 15.5 1.6 0.0075 15.1 1.1 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.18 ETO01653.1 - 0.017 14.8 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family TPR_12 PF13424.1 ETO01654.1 - 5.2e-108 353.1 30.6 2.5e-26 91.3 0.2 5.1 1 1 6 7 7 7 6 Tetratricopeptide repeat TPR_10 PF13374.1 ETO01654.1 - 1.5e-41 139.1 0.0 8.3e-08 31.9 0.0 6.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETO01654.1 - 3e-40 135.6 23.2 8.5e-15 54.1 0.4 4.5 3 1 2 5 5 5 4 TPR repeat TPR_1 PF00515.23 ETO01654.1 - 2.3e-37 125.1 34.9 3e-08 32.9 0.2 7.0 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.1 ETO01654.1 - 1.9e-36 120.9 11.4 1.9e-06 27.2 0.0 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETO01654.1 - 9.8e-33 109.4 24.0 2e-06 27.2 0.4 6.6 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETO01654.1 - 7.5e-26 87.9 38.4 4.3e-06 26.1 1.4 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 ETO01654.1 - 1.6e-18 65.2 10.9 0.0021 18.0 0.1 6.4 5 1 2 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO01654.1 - 4.9e-12 46.1 0.0 0.0033 18.0 0.0 5.0 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO01654.1 - 2.9e-10 39.8 0.0 4.3 8.2 0.0 5.9 6 0 0 6 6 5 1 Tetratricopeptide repeat SNAP PF14938.1 ETO01654.1 - 6.9e-08 31.9 8.4 0.0024 17.0 0.1 3.4 1 1 2 3 3 3 2 Soluble NSF attachment protein, SNAP TPR_3 PF07720.7 ETO01654.1 - 8.5e-08 31.8 18.8 0.081 12.7 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO01654.1 - 1.4e-07 31.5 8.6 0.99 10.0 0.1 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat PPR PF01535.15 ETO01654.1 - 2.2e-07 30.3 12.5 0.49 10.4 0.1 5.7 5 0 0 5 5 5 3 PPR repeat Apc3 PF12895.2 ETO01654.1 - 1.5e-06 28.2 20.2 0.0022 18.0 1.9 4.2 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO01654.1 - 1.1e-05 25.6 1.2 2.4 8.5 0.0 4.2 3 1 2 5 5 5 3 Tetratricopeptide repeat MIT PF04212.13 ETO01654.1 - 0.00011 22.0 14.9 2.8 7.9 0.0 6.0 6 0 0 6 6 6 1 MIT (microtubule interacting and transport) domain Pep3_Vps18 PF05131.9 ETO01654.1 - 0.00033 20.1 3.9 2.4 7.5 0.0 4.7 5 0 0 5 5 5 1 Pep3/Vps18/deep orange family Ten1_2 PF15490.1 ETO01654.1 - 0.0015 18.1 0.0 12 5.5 0.0 4.3 1 1 4 5 5 5 0 Telomere-capping, CST complex subunit HisG PF01634.13 ETO01654.1 - 0.0033 17.0 0.4 8.5 5.9 0.0 3.6 2 1 2 4 4 4 0 ATP phosphoribosyltransferase DUF2850 PF11012.3 ETO01654.1 - 0.0079 16.3 0.0 11 6.2 0.0 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2850) Syntaxin_2 PF14523.1 ETO01654.1 - 0.014 15.3 0.0 21 5.2 0.0 3.7 2 1 1 3 3 3 0 Syntaxin-like protein Musclin PF11037.3 ETO01654.1 - 0.055 13.0 0.0 43 3.7 0.0 3.6 4 0 0 4 4 4 0 Insulin-resistance promoting peptide in skeletal muscle Sel1 PF08238.7 ETO01654.1 - 0.13 12.9 17.9 7 7.4 0.2 6.3 7 0 0 7 7 7 0 Sel1 repeat FATC PF02260.15 ETO01654.1 - 0.18 11.2 2.7 39 3.7 0.3 3.3 3 0 0 3 3 3 0 FATC domain DUF3450 PF11932.3 ETO01654.1 - 0.81 8.8 2.7 5.8 6.1 0.2 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3450) PPR_2 PF13041.1 ETO01654.1 - 1.6 8.7 5.4 10 6.2 0.1 3.8 4 0 0 4 4 4 0 PPR repeat family PsaN PF05479.6 ETO01654.1 - 2 8.4 4.9 21 5.0 0.0 3.5 4 1 1 5 5 3 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) DUF627 PF04781.7 ETO01654.1 - 5.9 6.5 15.0 5.2 6.7 0.1 5.2 3 1 2 6 6 6 0 Protein of unknown function (DUF627) LicD PF04991.8 ETO01655.1 - 0.032 14.3 7.0 0.031 14.3 4.1 1.3 1 1 0 1 1 1 0 LicD family BAAT_C PF08840.6 ETO01655.1 - 0.06 13.0 2.2 0.085 12.5 1.2 1.5 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal CALCOCO1 PF07888.6 ETO01655.1 - 0.086 11.1 13.2 0.13 10.5 9.2 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like RraB PF06877.6 ETO01655.1 - 0.29 11.8 4.4 0.67 10.6 3.0 1.7 1 0 0 1 1 1 0 Regulator of ribonuclease activity B GvpK PF05121.7 ETO01655.1 - 0.29 10.9 5.8 0.17 11.7 0.6 2.5 1 1 1 2 2 2 0 Gas vesicle protein K VSG_B PF13206.1 ETO01655.1 - 0.97 8.4 9.1 1.2 8.1 6.3 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain PAZ_siRNAbind PF12212.3 ETO01655.1 - 1.2 8.8 8.4 0.25 11.0 0.4 3.5 3 1 1 4 4 4 0 Piwi/Argonaute/Zwille siRNA-binding domain Latarcin PF10279.4 ETO01655.1 - 1.6 8.9 11.7 0.21 11.7 2.7 2.5 2 1 1 3 3 3 0 Latarcin precursor FlxA PF14282.1 ETO01655.1 - 2 8.4 19.8 0.2 11.6 2.0 2.6 1 1 1 2 2 2 0 FlxA-like protein DUF2968 PF11180.3 ETO01655.1 - 2.9 7.2 13.4 0.17 11.2 5.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Viral_P18 PF04521.8 ETO01655.1 - 4.5 6.7 17.1 0.62 9.5 0.7 2.7 2 1 1 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein GDI PF00996.13 ETO01656.1 - 2.6e-39 134.7 0.1 5.4e-39 133.7 0.1 1.4 1 1 0 1 1 1 1 GDP dissociation inhibitor DUF262 PF03235.9 ETO01656.1 - 0.1 12.5 7.2 0.038 13.9 3.2 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF262 FRG PF08867.6 ETO01657.1 - 0.0065 16.9 0.6 0.012 16.1 0.3 1.6 1 1 0 1 1 1 1 FRG domain EpoR_lig-bind PF09067.5 ETO01657.1 - 0.026 14.4 0.2 0.048 13.6 0.1 1.4 1 0 0 1 1 1 0 Erythropoietin receptor, ligand binding SBP PF03110.9 ETO01657.1 - 0.1 12.8 1.2 0.17 12.1 0.1 1.9 2 1 1 3 3 3 0 SBP domain Acetyltransf_13 PF13880.1 ETO01657.1 - 0.11 12.2 0.0 1.9 8.2 0.0 2.2 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase IpaB_EvcA PF03278.8 ETO01657.1 - 0.67 9.1 3.8 0.69 9.1 0.3 2.1 1 1 0 2 2 2 0 IpaB/EvcA family WD40 PF00400.27 ETO01658.1 - 8.2e-18 63.5 0.4 4.8e-13 48.4 0.1 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO01658.1 - 0.0015 16.7 0.0 0.0015 16.7 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 DsrC PF04358.8 ETO01659.1 - 0.071 13.3 0.1 0.14 12.4 0.0 1.5 1 1 0 1 1 1 0 DsrC like protein Zip PF02535.17 ETO01660.1 - 0.0031 16.5 10.0 0.0053 15.7 7.0 1.5 1 0 0 1 1 1 1 ZIP Zinc transporter CDC45 PF02724.9 ETO01660.1 - 0.037 12.0 5.1 0.036 12.0 3.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 ETO01660.1 - 0.097 10.5 10.4 0.13 10.1 7.2 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 ETO01660.1 - 1.2 8.3 10.6 1.6 7.9 7.3 1.2 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.7 ETO01660.1 - 1.7 6.9 13.2 2.4 6.4 9.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Daxx PF03344.10 ETO01660.1 - 2.7 6.3 10.5 3.5 5.9 7.3 1.1 1 0 0 1 1 1 0 Daxx Family DEAD PF00270.24 ETO01662.1 - 9e-11 41.5 0.1 1.1e-09 38.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase DEP PF00610.16 ETO01664.1 - 1.4e-22 79.1 0.1 2.3e-22 78.5 0.1 1.3 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FAD-oxidase_C PF02913.14 ETO01664.1 - 0.007 15.7 0.2 0.01 15.1 0.1 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain WD40 PF00400.27 ETO01665.1 - 3.6e-23 80.5 2.5 3.9e-12 45.5 0.1 3.7 3 1 0 3 3 3 3 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO01665.1 - 0.081 13.1 3.0 11 6.4 0.1 3.5 2 2 1 3 3 3 0 Kelch motif MIP-T3 PF10243.4 ETO01666.1 - 0.00097 17.7 35.7 0.001 17.6 24.7 1.0 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Vfa1 PF08432.5 ETO01666.1 - 0.039 13.9 28.4 0.048 13.6 19.7 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1777 PF08648.7 ETO01666.1 - 2.6 7.7 57.4 1.2e+02 2.3 39.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) DUF1510 PF07423.6 ETO01666.1 - 3 7.1 31.7 3.6 6.9 22.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DSL PF01414.14 ETO01667.1 - 1.4 8.9 9.6 1.1 9.3 2.0 2.4 2 0 0 2 2 2 0 Delta serrate ligand SecA_DEAD PF07517.9 ETO01668.1 - 9.8e-09 34.8 0.0 9.8e-09 34.8 0.0 3.9 2 1 1 3 3 3 1 SecA DEAD-like domain DUF948 PF06103.6 ETO01668.1 - 3.5 7.5 15.1 7.6 6.4 0.7 5.1 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF2358 PF10184.4 ETO01670.1 - 0.0045 16.8 0.0 0.02 14.8 0.0 1.9 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2358) Fip1 PF05182.8 ETO01671.1 - 7.9e-20 69.8 2.8 1.4e-19 69.0 1.9 1.4 1 0 0 1 1 1 1 Fip1 motif DUF4014 PF13198.1 ETO01673.1 - 0.0038 17.6 0.1 0.0074 16.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4014) NACHT PF05729.7 ETO01673.1 - 0.12 12.0 0.0 0.31 10.6 0.0 1.7 2 0 0 2 2 2 0 NACHT domain tRNA-synt_2 PF00152.15 ETO01674.1 - 2.9e-26 92.0 0.5 3.1e-26 91.9 0.3 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Lact-deh-memb PF09330.6 ETO01675.1 - 0.072 12.4 1.5 0.08 12.3 1.0 1.1 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding Trigger_N PF05697.8 ETO01676.1 - 0.16 11.7 0.7 0.19 11.5 0.5 1.1 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) DUF3979 PF13141.1 ETO01676.1 - 0.17 11.7 1.9 0.2 11.5 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3979) PPR_2 PF13041.1 ETO01678.1 - 2.9e-13 49.5 2.3 1.7e-08 34.3 0.1 3.5 2 1 1 3 3 3 3 PPR repeat family PPR_3 PF13812.1 ETO01678.1 - 1.3e-10 40.6 0.0 3.1e-05 23.9 0.0 3.8 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.15 ETO01678.1 - 2.2e-08 33.5 0.7 0.00049 19.8 0.0 3.2 3 0 0 3 3 3 2 PPR repeat PPR_1 PF12854.2 ETO01678.1 - 4.1e-08 32.5 0.4 0.0052 16.2 0.0 3.4 3 0 0 3 3 3 3 PPR repeat DUF1350 PF07082.6 ETO01679.1 - 0.11 11.4 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1350) Guanylate_cyc PF00211.15 ETO01680.1 - 2.4e-20 72.6 0.8 7e-20 71.1 0.6 1.7 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF258 PF03193.11 ETO01683.1 - 3.4e-05 23.0 1.0 0.00032 19.9 0.1 2.8 2 1 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 ETO01683.1 - 0.00051 19.9 0.1 0.00051 19.9 0.0 3.2 4 0 0 4 4 4 1 50S ribosome-binding GTPase AAA_22 PF13401.1 ETO01683.1 - 0.0038 17.3 2.9 0.042 14.0 0.0 3.5 4 0 0 4 4 4 1 AAA domain ABC_tran PF00005.22 ETO01683.1 - 0.0045 17.3 0.0 0.0045 17.3 0.0 3.1 3 0 0 3 3 3 1 ABC transporter AAA_29 PF13555.1 ETO01683.1 - 0.0085 15.6 0.1 0.021 14.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 ETO01683.1 - 0.011 14.6 0.0 0.031 13.1 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein rve_3 PF13683.1 ETO01683.1 - 0.013 15.0 0.1 0.2 11.1 0.0 2.8 2 0 0 2 2 2 0 Integrase core domain AAA_16 PF13191.1 ETO01683.1 - 0.02 14.8 1.5 0.49 10.3 0.0 2.9 3 1 0 3 3 3 0 AAA ATPase domain AAA_28 PF13521.1 ETO01683.1 - 0.038 13.9 0.1 0.13 12.1 0.1 2.0 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 ETO01683.1 - 0.063 12.6 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain SprA-related PF12118.3 ETO01683.1 - 4.2 6.6 15.8 3.1 7.0 0.8 2.3 2 0 0 2 2 2 0 SprA-related family CDK5_activator PF03261.10 ETO01684.1 - 0.093 12.0 0.7 0.099 11.9 0.5 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein CDC45 PF02724.9 ETO01685.1 - 6.2e-05 21.2 10.4 7.1e-05 21.0 7.2 1.1 1 0 0 1 1 1 1 CDC45-like protein Cwf_Cwc_15 PF04889.7 ETO01685.1 - 0.0002 21.1 11.5 0.00022 21.0 8.0 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF1510 PF07423.6 ETO01685.1 - 0.0014 18.0 11.2 0.0016 17.8 7.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Nop14 PF04147.7 ETO01685.1 - 0.0032 15.4 18.5 0.0032 15.4 12.8 1.3 2 0 0 2 2 2 1 Nop14-like family SDA1 PF05285.7 ETO01685.1 - 0.011 15.0 18.0 0.014 14.6 12.5 1.2 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 ETO01685.1 - 0.013 14.0 16.1 0.016 13.7 11.2 1.1 1 0 0 1 1 1 0 Daxx Family NAM-associated PF14303.1 ETO01685.1 - 0.013 15.7 14.5 0.021 15.1 10.1 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Sporozoite_P67 PF05642.6 ETO01685.1 - 0.056 11.3 6.3 0.064 11.1 4.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop53 PF07767.6 ETO01685.1 - 0.07 12.1 18.0 0.1 11.5 12.4 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Hid1 PF12722.2 ETO01685.1 - 0.082 10.5 7.0 0.087 10.4 4.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.17 ETO01685.1 - 0.12 11.3 3.6 0.15 11.0 2.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Myc_N PF01056.13 ETO01685.1 - 0.14 11.2 5.7 0.2 10.7 4.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region PRP1_N PF06424.7 ETO01685.1 - 0.15 12.3 14.2 0.22 11.8 9.8 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DUF2201_N PF13203.1 ETO01685.1 - 0.15 11.1 7.3 0.18 10.9 5.1 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain CENP-T PF15511.1 ETO01685.1 - 0.22 10.7 10.5 0.29 10.3 7.2 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Raftlin PF15250.1 ETO01685.1 - 0.3 9.5 6.4 0.36 9.2 4.4 1.1 1 0 0 1 1 1 0 Raftlin Mem_trans PF03547.13 ETO01685.1 - 0.46 8.7 4.0 0.6 8.3 2.8 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF4614 PF15391.1 ETO01685.1 - 1 9.1 5.2 1.5 8.5 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) AIF_C PF14721.1 ETO01685.1 - 1.4 9.1 8.7 47 4.2 6.1 2.1 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term HSP90 PF00183.13 ETO01685.1 - 1.6 7.0 15.5 2.2 6.5 10.7 1.3 1 0 0 1 1 1 0 Hsp90 protein Peptidase_C37 PF05416.7 ETO01685.1 - 2.1 6.5 9.0 2.6 6.2 6.2 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Herpes_DNAp_acc PF04929.7 ETO01685.1 - 2.4 7.0 10.1 2.9 6.7 7.0 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Tom37_C PF11801.3 ETO01685.1 - 2.8 7.7 10.9 8.5 6.2 7.6 1.7 1 1 0 1 1 1 0 Tom37 C-terminal domain RNase_H2-Ydr279 PF09468.5 ETO01685.1 - 2.8 7.0 12.2 3.5 6.7 8.5 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DDHD PF02862.12 ETO01685.1 - 2.9 7.6 7.6 4 7.1 5.3 1.3 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 ETO01685.1 - 3 7.6 12.0 3.8 7.3 8.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ATP-synt_E PF05680.7 ETO01685.1 - 4.1 7.4 9.4 7.9 6.5 6.5 1.5 1 0 0 1 1 1 0 ATP synthase E chain Paf1 PF03985.8 ETO01685.1 - 4.9 5.7 22.2 6.4 5.3 15.4 1.1 1 0 0 1 1 1 0 Paf1 Sec62 PF03839.11 ETO01685.1 - 5.6 6.3 15.8 7.9 5.8 11.0 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 TRAP_alpha PF03896.11 ETO01685.1 - 6.6 5.6 8.2 8.6 5.2 5.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4220 PF13968.1 ETO01685.1 - 9.8 5.1 6.3 13 4.7 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Peptidase_C14 PF00656.17 ETO01686.1 - 0.12 12.1 0.1 0.17 11.5 0.1 1.6 1 1 0 1 1 1 0 Caspase domain dTMP_synthase PF02593.9 ETO01687.1 - 0.096 12.0 1.5 0.12 11.7 1.0 1.1 1 0 0 1 1 1 0 Thymidylate synthase Kelch_1 PF01344.20 ETO01689.1 - 2.7e-11 42.8 5.9 6.7e-07 28.7 0.8 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.10 ETO01689.1 - 3.2e-08 33.0 1.0 5.7e-05 22.7 0.2 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.1 ETO01689.1 - 3.2e-08 33.3 0.2 0.0012 18.7 0.3 2.4 2 1 0 2 2 2 2 Kelch motif Kelch_6 PF13964.1 ETO01689.1 - 6.2e-08 32.4 0.7 0.00051 20.0 0.2 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 ETO01689.1 - 1.3e-06 28.3 0.6 0.00056 19.9 0.0 2.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO01689.1 - 1.4e-06 27.9 0.1 0.012 15.4 0.1 2.4 2 0 0 2 2 2 2 Galactose oxidase, central domain WD40 PF00400.27 ETO01691.1 - 3.7e-13 48.8 3.8 4.4e-09 35.8 0.0 2.6 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF3785 PF12653.2 ETO01692.1 - 0.0086 15.9 1.3 0.01 15.6 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3785) DUF261 PF03196.8 ETO01692.1 - 0.01 15.7 1.7 0.015 15.2 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF261 Cullin_Nedd8 PF10557.4 ETO01692.1 - 0.073 12.9 0.1 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 Cullin protein neddylation domain Cytochrom_B562 PF07361.6 ETO01693.1 - 0.0023 18.2 0.4 0.0061 16.9 0.3 1.7 1 0 0 1 1 1 1 Cytochrome b562 DUF1524 PF07510.6 ETO01693.1 - 0.059 13.2 0.6 0.1 12.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1524) Nsp1_C PF05064.8 ETO01693.1 - 0.1 12.2 4.2 0.051 13.2 1.2 1.8 2 0 0 2 2 2 0 Nsp1-like C-terminal region HTH_44 PF14641.1 ETO01695.1 - 0.13 12.2 1.8 0.16 11.9 0.2 1.8 2 1 0 2 2 2 0 Helix-turn-helix DNA-binding domain of SPT6 DUF4407 PF14362.1 ETO01696.1 - 0.32 9.9 21.7 0.43 9.5 15.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Viral_DNA_bp PF00747.12 ETO01696.1 - 0.34 8.0 10.9 0.4 7.8 7.6 1.0 1 0 0 1 1 1 0 ssDNA binding protein AAA_13 PF13166.1 ETO01696.1 - 0.44 8.9 33.0 0.56 8.6 22.9 1.2 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 ETO01696.1 - 0.6 7.3 33.0 0.73 7.0 22.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Peptidase_C6 PF00851.13 ETO01696.1 - 0.89 8.1 20.2 1.1 7.8 14.0 1.3 1 0 0 1 1 1 0 Helper component proteinase Mitofilin PF09731.4 ETO01696.1 - 1 7.9 27.5 1.1 7.8 19.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Reo_sigmaC PF04582.7 ETO01696.1 - 1.1 8.3 4.6 1.3 8.1 3.2 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein ADIP PF11559.3 ETO01696.1 - 1.2 9.0 41.2 0.34 10.8 19.3 2.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.4 ETO01696.1 - 1.6 7.6 36.5 11 4.8 25.3 2.0 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CHASE3 PF05227.8 ETO01696.1 - 1.6 8.4 19.4 3 7.5 1.4 2.8 1 1 1 2 2 2 0 CHASE3 domain MCPsignal PF00015.16 ETO01696.1 - 1.8 8.0 14.6 0.64 9.5 3.2 2.0 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Herpes_UL25 PF01499.11 ETO01696.1 - 2 6.6 14.1 2.3 6.4 9.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF1266 PF06889.6 ETO01696.1 - 2.3 7.9 9.9 71 3.1 6.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1266) DNA_methylase PF00145.12 ETO01696.1 - 2.4 7.1 17.4 2.9 6.9 12.0 1.2 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase DUF4045 PF13254.1 ETO01696.1 - 3.3 6.9 17.6 3.8 6.6 12.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Phage_GP20 PF06810.6 ETO01696.1 - 3.5 7.0 46.1 3.7 6.9 8.4 3.1 1 1 2 3 3 3 0 Phage minor structural protein GP20 IncA PF04156.9 ETO01696.1 - 4.3 6.8 33.7 1.3 8.5 8.0 2.2 1 1 1 2 2 2 0 IncA protein Tyrosinase PF00264.15 ETO01696.1 - 4.8 7.2 10.7 5.3 7.1 7.4 1.2 1 0 0 1 1 1 0 Common central domain of tyrosinase Asp-B-Hydro_N PF05279.6 ETO01696.1 - 5.5 6.7 23.5 6.2 6.5 16.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region APG6 PF04111.7 ETO01696.1 - 6.5 5.6 40.0 1.9 7.4 17.1 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Mnd1 PF03962.10 ETO01696.1 - 6.6 6.3 36.7 1 8.9 21.6 2.1 1 1 1 2 2 2 0 Mnd1 family DUF4175 PF13779.1 ETO01696.1 - 7.4 4.1 29.1 8.5 3.9 20.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) ALMT PF11744.3 ETO01696.1 - 8.2 4.9 14.5 9.2 4.7 10.1 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF972 PF06156.8 ETO01696.1 - 8.9 6.7 35.3 5.2 7.4 8.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF3166 PF11365.3 ETO01696.1 - 9.5 6.7 18.4 5.2 7.5 1.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) IncA PF04156.9 ETO01699.1 - 0.0014 18.2 5.7 0.0028 17.2 3.9 1.5 1 0 0 1 1 1 1 IncA protein DUF1664 PF07889.7 ETO01699.1 - 0.13 12.0 5.4 0.15 11.8 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DivIC PF04977.10 ETO01699.1 - 0.75 9.3 5.0 2.3 7.7 3.5 1.9 1 0 0 1 1 1 0 Septum formation initiator SlyX PF04102.7 ETO01699.1 - 0.91 9.9 6.7 2.7 8.4 4.1 2.3 2 1 0 2 2 2 0 SlyX bZIP_2 PF07716.10 ETO01699.1 - 2 8.2 7.9 0.19 11.5 2.0 1.9 2 0 0 2 2 2 0 Basic region leucine zipper PUB PF09409.5 ETO01700.1 - 2.1 8.1 6.8 2.4 7.9 0.7 3.3 2 1 1 3 3 3 0 PUB domain TetR_C_8 PF14278.1 ETO01701.1 - 0.007 16.7 2.9 0.027 14.8 0.8 2.3 2 0 0 2 2 2 1 Transcriptional regulator C-terminal region IBR PF01485.16 ETO01701.1 - 0.026 14.4 2.6 0.22 11.4 1.8 2.4 1 1 0 1 1 1 0 IBR domain RGS PF00615.14 ETO01702.1 - 5.4e-05 23.2 2.9 0.00021 21.3 2.0 2.0 1 1 0 1 1 1 1 Regulator of G protein signaling domain WD40 PF00400.27 ETO01703.1 - 2e-58 192.3 23.9 3.2e-11 42.6 0.8 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat zf-TRAF PF02176.13 ETO01703.1 - 1.5e-05 25.2 5.7 1.5e-05 25.2 3.9 2.7 2 0 0 2 2 2 1 TRAF-type zinc finger Nup160 PF11715.3 ETO01703.1 - 0.00013 20.2 9.2 0.06 11.4 0.0 5.2 2 1 5 7 7 7 2 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO01703.1 - 0.012 15.4 1.0 1.2 9.1 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3601) CDO_I PF05995.7 ETO01703.1 - 0.39 9.8 0.0 0.39 9.8 0.0 2.7 3 0 0 3 3 3 0 Cysteine dioxygenase type I LMBR1 PF04791.11 ETO01703.1 - 1.2 7.6 4.9 1.6 7.2 3.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF763 PF05559.6 ETO01703.1 - 9.6 5.0 7.9 19 4.0 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Herpes_BLRF2 PF05812.7 ETO01704.1 - 0.0014 18.3 0.4 0.41 10.4 0.4 2.5 2 0 0 2 2 2 1 Herpesvirus BLRF2 protein SSP160 PF06933.6 ETO01704.1 - 0.0083 14.1 6.2 0.012 13.6 4.3 1.2 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 FlxA PF14282.1 ETO01704.1 - 0.018 14.9 4.8 0.018 14.9 3.3 2.5 3 0 0 3 3 2 0 FlxA-like protein DUF4618 PF15397.1 ETO01704.1 - 0.019 14.3 5.7 0.019 14.3 4.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) FTA4 PF13093.1 ETO01704.1 - 0.043 13.2 2.6 0.059 12.8 1.8 1.3 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 HALZ PF02183.13 ETO01704.1 - 0.052 13.2 6.4 1.2 8.8 0.9 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper CCDC155 PF14662.1 ETO01704.1 - 0.064 12.8 5.4 2.2 7.8 0.1 2.3 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 Shugoshin_N PF07558.6 ETO01704.1 - 0.081 12.6 6.3 2.3 7.9 0.7 2.6 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF972 PF06156.8 ETO01704.1 - 0.082 13.2 9.9 0.79 10.0 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF4200 PF13863.1 ETO01704.1 - 0.091 12.7 10.7 0.6 10.0 2.9 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF3439 PF11921.3 ETO01704.1 - 0.096 12.4 7.0 0.18 11.5 4.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PUB PF09409.5 ETO01704.1 - 0.1 12.3 1.1 1.5 8.6 0.1 2.2 2 0 0 2 2 2 0 PUB domain DivIVA PF05103.8 ETO01704.1 - 0.11 12.5 9.5 0.92 9.5 1.9 2.5 2 1 0 2 2 2 0 DivIVA protein DivIC PF04977.10 ETO01704.1 - 0.13 11.7 16.9 0.36 10.3 0.7 3.0 3 1 0 3 3 3 0 Septum formation initiator TSC22 PF01166.13 ETO01704.1 - 0.32 10.9 5.9 1.7 8.6 0.1 2.6 3 0 0 3 3 2 0 TSC-22/dip/bun family bZIP_2 PF07716.10 ETO01704.1 - 0.33 10.8 11.3 1 9.2 0.8 2.8 2 1 0 2 2 2 0 Basic region leucine zipper TPR_MLP1_2 PF07926.7 ETO01704.1 - 0.36 10.5 15.7 1.8 8.3 6.9 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Med9 PF07544.8 ETO01704.1 - 0.55 10.0 4.4 2 8.2 0.5 2.4 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Seryl_tRNA_N PF02403.17 ETO01704.1 - 0.83 9.6 11.7 0.25 11.3 4.3 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Tup_N PF08581.5 ETO01704.1 - 0.85 9.8 7.6 3.1 8.0 0.2 2.6 2 1 0 2 2 2 0 Tup N-terminal Cep57_CLD_2 PF14197.1 ETO01704.1 - 1.5 8.8 6.3 0.95 9.4 0.3 2.5 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Fmp27_WPPW PF10359.4 ETO01704.1 - 1.6 7.0 8.1 0.076 11.4 1.9 1.4 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain UPF0449 PF15136.1 ETO01704.1 - 1.8 8.7 7.8 4.1 7.6 1.6 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 KLRAQ PF10205.4 ETO01704.1 - 2.1 8.3 8.6 6.4 6.8 2.6 2.4 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein Syntaxin PF00804.20 ETO01704.1 - 2.4 8.3 10.2 64 3.7 7.0 2.4 1 1 0 1 1 1 0 Syntaxin Myosin_tail_1 PF01576.14 ETO01704.1 - 3.3 5.3 13.1 0.29 8.7 4.6 1.9 2 0 0 2 2 2 0 Myosin tail ERM PF00769.14 ETO01704.1 - 4.8 6.6 12.8 7 6.1 0.3 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF4337 PF14235.1 ETO01704.1 - 6.6 6.5 8.8 8.2 6.2 2.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) WD40 PF00400.27 ETO01707.1 - 8.9e-18 63.4 2.5 2.4e-08 33.5 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 ETO01707.1 - 8.1e-07 28.9 1.4 0.00094 18.9 0.1 2.7 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO01707.1 - 1.4e-05 24.6 10.7 2.2 8.0 0.2 5.9 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Kelch_1 PF01344.20 ETO01707.1 - 0.00011 21.7 0.0 0.00076 18.9 0.0 2.5 2 0 0 2 2 2 1 Kelch motif DPPIV_N PF00930.16 ETO01707.1 - 0.00027 19.6 3.2 0.58 8.6 1.6 4.1 1 1 1 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Kelch_6 PF13964.1 ETO01707.1 - 0.0017 18.4 0.3 0.18 12.0 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO01707.1 - 0.015 15.0 0.2 0.87 9.4 0.0 2.9 3 0 0 3 3 3 0 Kelch motif Cytochrom_D1 PF02239.11 ETO01707.1 - 0.025 12.8 0.1 1.7 6.8 0.0 2.3 1 1 1 2 2 2 0 Cytochrome D1 heme domain Lactonase PF10282.4 ETO01707.1 - 0.025 13.6 0.1 9.8 5.1 0.0 3.3 2 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller GF_recep_IV PF14843.1 ETO01708.1 - 0.13 11.8 3.2 0.18 11.4 2.2 1.2 1 0 0 1 1 1 0 Growth factor receptor domain IV Kelch_1 PF01344.20 ETO01708.1 - 0.64 9.6 6.8 0.46 10.0 0.1 3.1 4 0 0 4 4 4 0 Kelch motif NACHT PF05729.7 ETO01709.1 - 2.4e-09 37.0 0.0 7.8e-09 35.3 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO01709.1 - 9.9e-05 22.6 0.8 0.0028 17.9 0.0 3.5 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.1 ETO01709.1 - 0.0012 18.9 0.0 0.0075 16.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 ETO01709.1 - 0.0019 17.7 0.1 0.036 13.6 0.0 2.8 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 ETO01709.1 - 0.02 15.7 0.2 0.2 12.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 ETO01709.1 - 0.049 13.9 0.5 0.85 9.9 0.0 2.8 2 0 0 2 2 2 0 ABC transporter AAA PF00004.24 ETO01709.1 - 0.052 13.7 0.0 0.18 11.9 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 ETO01709.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETO01709.1 - 0.13 12.2 0.1 1 9.3 0.0 2.3 1 1 1 2 2 2 0 AAA ATPase domain WD40 PF00400.27 ETO01710.1 - 4e-133 429.1 37.0 1.8e-12 46.6 0.1 14.8 13 2 1 14 14 14 14 WD domain, G-beta repeat PD40 PF07676.7 ETO01710.1 - 3.2e-05 23.4 15.6 1.5 8.5 0.0 8.0 9 0 0 9 9 9 2 WD40-like Beta Propeller Repeat Pentapeptide_4 PF13599.1 ETO01710.1 - 3.6e-05 23.4 0.2 0.00014 21.5 0.2 2.0 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETO01710.1 - 3.6e-05 22.8 1.8 4.9e-05 22.4 0.3 2.0 2 0 0 2 2 2 1 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 ETO01710.1 - 0.00014 21.6 0.6 0.00053 19.8 0.2 2.2 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) Cytochrom_D1 PF02239.11 ETO01710.1 - 0.0002 19.7 2.9 0.08 11.2 0.0 4.6 4 1 1 5 5 5 1 Cytochrome D1 heme domain DUF1938 PF09153.5 ETO01710.1 - 0.00031 20.4 0.2 5.3 6.9 0.0 5.4 4 1 1 5 5 5 1 Domain of unknown function (DUF1938) SGL PF08450.7 ETO01710.1 - 0.00053 19.4 0.3 0.35 10.1 0.0 4.4 4 1 0 4 4 4 1 SMP-30/Gluconolaconase/LRE-like region DUF4073 PF13285.1 ETO01710.1 - 0.011 15.1 2.2 3.1 7.2 1.6 3.9 5 0 0 5 5 5 0 Domain of unknown function (DUF4073) Corona_NS8 PF12093.3 ETO01710.1 - 0.12 12.6 0.9 20 5.5 0.0 3.8 4 0 0 4 4 4 0 Coronavirus NS8 protein CAP_GLY PF01302.20 ETO01711.1 - 0.0066 16.1 0.1 0.019 14.6 0.0 1.9 1 1 0 1 1 1 1 CAP-Gly domain MMR_HSR1 PF01926.18 ETO01713.1 - 6.4e-06 26.1 0.1 1.8e-05 24.6 0.0 1.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase Septin PF00735.13 ETO01713.1 - 8.9e-06 24.9 0.4 2.6e-05 23.3 0.1 1.8 1 1 1 2 2 2 1 Septin Gtr1_RagA PF04670.7 ETO01713.1 - 2.3e-05 23.6 0.2 8.6e-05 21.7 0.0 2.0 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 ETO01713.1 - 7.2e-05 22.2 0.1 0.0004 19.8 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 ETO01713.1 - 0.00012 21.2 0.2 0.00036 19.7 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 ETO01713.1 - 0.00013 21.1 0.4 0.0011 18.1 0.0 2.1 1 1 1 2 2 2 1 AIG1 family AAA_29 PF13555.1 ETO01713.1 - 0.0013 18.1 0.1 0.0033 16.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain G-alpha PF00503.15 ETO01713.1 - 0.019 13.7 0.4 0.023 13.4 0.3 1.5 1 1 0 1 1 1 0 G-protein alpha subunit AAA_16 PF13191.1 ETO01713.1 - 0.022 14.7 0.1 0.034 14.1 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 ETO01713.1 - 0.026 13.6 0.0 0.096 11.7 0.0 1.9 2 1 0 2 2 2 0 Zeta toxin Myosin_head PF00063.16 ETO01713.1 - 0.026 12.5 0.0 0.047 11.7 0.0 1.4 1 1 0 1 1 1 0 Myosin head (motor domain) PduV-EutP PF10662.4 ETO01713.1 - 0.03 13.8 0.0 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 ETO01713.1 - 0.03 14.6 0.6 0.045 14.0 0.4 1.6 1 1 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.12 ETO01713.1 - 0.031 13.7 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_23 PF13476.1 ETO01713.1 - 0.032 14.5 1.7 0.053 13.8 0.8 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 ETO01713.1 - 0.067 13.3 1.2 0.13 12.4 0.2 2.2 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 ETO01713.1 - 0.14 11.9 1.1 0.43 10.3 0.8 2.1 1 1 0 1 1 1 0 Dynamin family GP120 PF00516.13 ETO01714.1 - 0.0013 17.0 1.2 0.0016 16.7 0.8 1.1 1 0 0 1 1 1 1 Envelope glycoprotein GP120 Ribosomal_L14e PF01929.12 ETO01714.1 - 0.33 11.3 8.0 0.96 9.8 5.5 1.8 1 0 0 1 1 1 0 Ribosomal protein L14 Dehydrin PF00257.14 ETO01715.1 - 0.0015 18.9 1.1 0.042 14.1 0.0 2.3 1 1 1 2 2 2 1 Dehydrin CLPTM1 PF05602.7 ETO01715.1 - 0.01 14.6 7.7 0.011 14.4 5.4 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) CENP-B_dimeris PF09026.5 ETO01715.1 - 0.015 15.4 9.3 0.32 11.2 1.4 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Mucin PF01456.12 ETO01715.1 - 0.083 12.6 29.4 0.12 12.1 20.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Med3 PF11593.3 ETO01715.1 - 1.6 7.8 13.2 2 7.5 9.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal BSP_II PF05432.6 ETO01715.1 - 5.2 6.2 29.4 3.2 6.9 9.1 2.2 1 1 1 2 2 2 0 Bone sialoprotein II (BSP-II) MGC-24 PF05283.6 ETO01715.1 - 6.4 6.5 18.3 12 5.6 12.7 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) DEAD PF00270.24 ETO01718.1 - 5.2e-23 81.3 0.0 6.5e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 ETO01718.1 - 0.00013 21.8 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 ETO01718.1 - 0.027 13.7 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 SecA DEAD-like domain Flavi_DEAD PF07652.9 ETO01718.1 - 0.13 12.0 0.1 2.7 7.7 0.0 2.3 2 1 1 3 3 3 0 Flavivirus DEAD domain zf-CCHC PF00098.18 ETO01719.1 - 0.06 13.3 1.6 0.06 13.3 1.1 1.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 ETO01719.1 - 0.16 11.6 5.9 0.26 11.0 1.2 2.4 2 0 0 2 2 2 0 Zinc knuckle TLD PF07534.11 ETO01720.1 - 5.3e-13 49.1 1.9 7.5e-13 48.6 1.3 1.2 1 0 0 1 1 1 1 TLD Endonuc_subdom PF09062.5 ETO01721.1 - 2.6 8.8 6.7 26 5.6 0.3 3.4 3 0 0 3 3 3 0 PI-PfuI Endonuclease subdomain HEAT PF02985.17 ETO01722.1 - 0.035 14.1 0.0 0.069 13.2 0.0 1.5 1 0 0 1 1 1 0 HEAT repeat TPR_12 PF13424.1 ETO01726.1 - 3.1e-223 722.3 39.8 3.4e-27 94.2 0.1 7.9 1 1 8 10 10 10 10 Tetratricopeptide repeat TPR_11 PF13414.1 ETO01726.1 - 1.4e-99 325.8 48.5 4.3e-18 64.7 0.6 7.1 3 2 4 8 8 8 8 TPR repeat TPR_7 PF13176.1 ETO01726.1 - 2.4e-92 295.5 25.4 8.6e-09 34.5 0.0 11.2 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_10 PF13374.1 ETO01726.1 - 2.7e-86 281.3 0.0 1.4e-09 37.5 0.0 12.0 12 0 0 12 12 12 11 Tetratricopeptide repeat TPR_1 PF00515.23 ETO01726.1 - 1.8e-83 270.9 67.9 1.9e-09 36.7 0.3 11.9 12 0 0 12 12 12 11 Tetratricopeptide repeat TPR_2 PF07719.12 ETO01726.1 - 6.2e-71 228.7 39.9 1.4e-07 30.8 0.1 11.4 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_8 PF13181.1 ETO01726.1 - 1.1e-67 218.8 79.1 3.8e-09 35.6 0.7 11.3 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_17 PF13431.1 ETO01726.1 - 1.5e-43 143.3 20.3 0.00077 19.4 0.0 12.1 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_16 PF13432.1 ETO01726.1 - 2.9e-34 116.9 0.0 1.6e-05 25.4 0.0 9.2 4 3 6 10 10 10 7 Tetratricopeptide repeat TPR_14 PF13428.1 ETO01726.1 - 9.9e-32 106.5 0.0 0.087 13.5 0.0 10.7 9 2 2 11 11 10 5 Tetratricopeptide repeat TPR_6 PF13174.1 ETO01726.1 - 1.6e-24 84.5 12.2 0.064 13.7 0.0 11.2 11 0 0 11 11 11 6 Tetratricopeptide repeat Apc3 PF12895.2 ETO01726.1 - 1.2e-21 76.6 31.6 2.3e-05 24.4 0.9 6.4 1 1 4 7 7 7 7 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.1 ETO01726.1 - 1.1e-20 73.9 19.7 3.6e-07 29.6 0.5 6.0 1 1 0 4 4 4 4 Soluble NSF attachment protein, SNAP TPR_19 PF14559.1 ETO01726.1 - 2.7e-19 69.2 3.3 0.0057 16.9 0.0 7.6 3 2 6 9 9 9 6 Tetratricopeptide repeat PPR PF01535.15 ETO01726.1 - 1.7e-18 65.2 31.5 0.15 12.1 0.1 10.4 10 0 0 10 10 10 6 PPR repeat TPR_3 PF07720.7 ETO01726.1 - 8.7e-14 50.9 41.7 0.032 14.0 0.1 10.2 10 0 0 10 10 9 6 Tetratricopeptide repeat Ten1_2 PF15490.1 ETO01726.1 - 1e-10 41.2 0.0 4.6 6.8 0.0 8.8 1 1 10 11 11 11 0 Telomere-capping, CST complex subunit DUF627 PF04781.7 ETO01726.1 - 1.7e-10 40.4 20.3 0.19 11.3 0.0 9.0 2 2 7 9 9 9 1 Protein of unknown function (DUF627) MIT PF04212.13 ETO01726.1 - 8e-09 35.2 51.0 0.35 10.7 0.4 10.6 10 1 1 11 11 10 5 MIT (microtubule interacting and transport) domain DUF3568 PF12092.3 ETO01726.1 - 5.4e-08 32.6 0.3 6.6 6.4 0.0 6.6 1 1 4 8 8 8 0 Protein of unknown function (DUF3568) RPN7 PF10602.4 ETO01726.1 - 5.7e-08 32.3 26.8 0.76 9.1 0.1 9.2 3 2 5 10 10 10 2 26S proteasome subunit RPN7 Sel1 PF08238.7 ETO01726.1 - 1.2e-07 32.1 29.5 2.2 9.0 0.1 9.6 9 0 0 9 9 9 1 Sel1 repeat Tnp_P_element PF12017.3 ETO01726.1 - 1.5e-07 30.8 1.4 0.63 9.2 0.0 5.9 2 1 2 6 6 6 1 Transposase protein SHNi-TPR PF10516.4 ETO01726.1 - 4.3e-07 29.0 4.0 0.51 9.6 0.0 7.3 9 0 0 9 9 8 1 SHNi-TPR TPR_9 PF13371.1 ETO01726.1 - 1.4e-06 28.0 0.0 2.5 8.0 0.0 5.5 4 3 3 7 7 7 2 Tetratricopeptide repeat Rab5-bind PF09311.6 ETO01726.1 - 7.2e-06 26.0 0.0 0.21 11.4 0.0 4.1 4 1 0 4 4 4 1 Rabaptin-like protein Mob_Pre PF01076.14 ETO01726.1 - 2.6e-05 23.9 16.6 0.35 10.4 0.3 5.9 2 2 6 8 8 7 3 Plasmid recombination enzyme Musclin PF11037.3 ETO01726.1 - 5.5e-05 22.7 0.0 66 3.1 0.0 7.5 9 1 2 11 11 10 0 Insulin-resistance promoting peptide in skeletal muscle PPR_2 PF13041.1 ETO01726.1 - 0.00011 22.0 19.3 6.8 6.7 0.0 8.9 9 1 1 10 10 9 0 PPR repeat family Mad3_BUB1_I PF08311.7 ETO01726.1 - 0.0004 20.1 16.6 5.5 6.7 0.0 8.5 10 0 0 10 10 10 0 Mad3/BUB1 homology region 1 Syntaxin_2 PF14523.1 ETO01726.1 - 0.0012 18.7 0.0 65 3.6 0.0 6.4 4 3 3 8 8 8 0 Syntaxin-like protein UPF0223 PF05256.7 ETO01726.1 - 0.0015 18.6 14.8 4.8 7.3 0.1 7.1 2 1 5 8 8 8 0 Uncharacterised protein family (UPF0223) Baculo_19 PF04798.7 ETO01726.1 - 0.011 15.1 10.3 9.9 5.5 0.0 5.9 4 3 4 8 8 8 0 Baculovirus 19 kDa protein conserved region DLD PF14878.1 ETO01726.1 - 0.014 15.4 5.5 10 6.2 0.0 6.3 4 3 4 8 8 7 0 Death-like domain of SPT6 ATP-synt_E_2 PF08112.6 ETO01726.1 - 0.015 15.3 33.2 3 7.9 0.1 9.1 9 0 0 9 9 8 0 ATP synthase epsilon subunit bPH_3 PF14470.1 ETO01726.1 - 0.025 14.8 12.5 74 3.6 0.1 6.7 2 2 5 8 8 8 0 Bacterial PH domain SERTA PF06031.8 ETO01726.1 - 0.026 13.7 2.8 44 3.4 0.0 5.6 8 0 0 8 8 7 0 SERTA motif TPR_15 PF13429.1 ETO01726.1 - 0.046 12.7 2.6 13 4.7 0.1 4.7 5 1 1 6 6 5 0 Tetratricopeptide repeat OEP PF02321.13 ETO01726.1 - 0.052 13.1 0.9 54 3.3 0.0 4.0 4 1 0 5 5 4 0 Outer membrane efflux protein Med31 PF05669.7 ETO01726.1 - 0.24 11.1 4.5 6.1 6.6 0.1 3.4 2 1 0 3 3 2 0 SOH1 TPR_21 PF09976.4 ETO01726.1 - 1.1 9.1 9.8 59 3.5 0.1 6.1 6 2 0 6 6 6 0 Tetratricopeptide repeat FATC PF02260.15 ETO01726.1 - 2.7 7.5 6.6 1.1e+02 2.4 0.0 4.8 5 0 0 5 5 5 0 FATC domain RR_TM4-6 PF06459.7 ETO01727.1 - 0.77 9.6 13.8 0.99 9.2 9.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CPSF100_C PF13299.1 ETO01727.1 - 1.7 8.8 10.2 2.5 8.2 7.1 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.12 ETO01727.1 - 1.7 7.3 6.5 2 7.1 4.5 1.1 1 0 0 1 1 1 0 Presenilin TMEM51 PF15345.1 ETO01727.1 - 4.2 7.0 8.6 5.3 6.6 6.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 DUF3573 PF12097.3 ETO01727.1 - 9.3 4.7 7.4 13 4.2 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DDHD PF02862.12 ETO01727.1 - 9.7 5.9 10.4 13 5.4 7.2 1.3 1 0 0 1 1 1 0 DDHD domain DUF3807 PF12720.2 ETO01727.1 - 9.8 6.2 14.3 17 5.4 9.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF2776 PF10951.3 ETO01728.1 - 0.02 13.9 0.0 0.025 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2776) Crl PF07417.7 ETO01728.1 - 0.076 12.7 0.3 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 Transcriptional regulator Crl TLD PF07534.11 ETO01729.1 - 0.0014 18.6 0.2 0.57 10.1 0.0 2.2 2 0 0 2 2 2 2 TLD DUF4207 PF13904.1 ETO01732.1 - 6.6e-07 28.9 26.6 9.2e-07 28.5 18.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) CAF-1_p150 PF11600.3 ETO01732.1 - 5.8 6.2 58.4 3.8 6.8 12.8 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TAP42 PF04177.7 ETO01733.1 - 0.041 12.8 0.4 0.048 12.5 0.3 1.2 1 0 0 1 1 1 0 TAP42-like family DUF444 PF04285.7 ETO01733.1 - 0.053 12.1 0.1 0.063 11.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF444) COX16 PF14138.1 ETO01733.1 - 0.12 12.5 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 Memo PF01875.12 ETO01734.1 - 1.7e-54 184.6 0.0 8.4e-54 182.3 0.0 2.0 2 1 0 2 2 2 1 Memo-like protein SGT1 PF07093.6 ETO01734.1 - 0.00021 19.8 4.0 0.00028 19.4 2.8 1.1 1 0 0 1 1 1 1 SGT1 protein Nop14 PF04147.7 ETO01734.1 - 0.073 10.9 22.2 0.11 10.3 15.4 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 ETO01734.1 - 5.4 4.9 20.4 8 4.3 14.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 ETO01734.1 - 5.4 5.6 39.5 9.8 4.7 27.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Hid1 PF12722.2 ETO01734.1 - 5.6 4.5 8.8 8 3.9 6.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Astro_capsid PF03115.9 ETO01734.1 - 6.9 4.7 10.3 10 4.2 7.2 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor RVT_connect PF06815.8 ETO01737.1 - 0.089 12.6 3.0 0.18 11.7 2.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase connection domain Slx4 PF09494.5 ETO01738.1 - 0.064 13.0 0.5 0.16 11.7 0.3 1.6 1 0 0 1 1 1 0 Slx4 endonuclease TPR_12 PF13424.1 ETO01739.1 - 3.4e-19 68.5 0.0 7.2e-19 67.5 0.0 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETO01739.1 - 4.8e-12 45.3 0.0 1.7e-08 34.0 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO01739.1 - 2.4e-10 39.8 0.7 3.7e-10 39.3 0.5 1.3 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 ETO01739.1 - 5.7e-10 38.3 4.9 0.00013 21.3 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO01739.1 - 6.4e-09 35.0 1.0 0.0014 18.4 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO01739.1 - 9.9e-08 31.6 0.3 0.033 14.3 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO01739.1 - 4.2e-07 29.2 6.5 0.0011 18.5 0.5 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO01739.1 - 1e-06 28.0 0.2 0.00069 19.2 0.0 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat PPR PF01535.15 ETO01739.1 - 0.00031 20.5 1.3 0.0034 17.2 0.1 2.3 2 0 0 2 2 2 1 PPR repeat Cohesin_load PF10345.4 ETO01739.1 - 0.00095 17.4 4.8 0.00095 17.4 3.3 1.6 1 1 1 2 2 2 1 Cohesin loading factor Apc3 PF12895.2 ETO01739.1 - 0.0094 16.0 3.6 0.028 14.5 0.7 2.1 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.1 ETO01739.1 - 0.01 15.0 0.4 0.014 14.5 0.3 1.3 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_21 PF09976.4 ETO01739.1 - 0.028 14.3 0.0 0.27 11.1 0.0 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat PPR_2 PF13041.1 ETO01739.1 - 0.037 14.0 0.3 0.39 10.7 0.1 2.2 2 0 0 2 2 2 0 PPR repeat family SHNi-TPR PF10516.4 ETO01739.1 - 0.052 12.7 0.0 1 8.6 0.0 2.3 2 0 0 2 2 2 0 SHNi-TPR Pep3_Vps18 PF05131.9 ETO01739.1 - 0.055 12.9 0.5 2.3 7.6 0.0 2.2 2 0 0 2 2 2 0 Pep3/Vps18/deep orange family DUF627 PF04781.7 ETO01739.1 - 0.16 11.5 3.7 1.1 8.8 0.2 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF627) MIT PF04212.13 ETO01739.1 - 0.26 11.1 1.7 1.4 8.8 0.4 2.2 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain AAA PF00004.24 ETO01740.1 - 0.00085 19.5 0.0 0.0026 17.9 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETO01740.1 - 0.056 13.5 0.0 0.18 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 ETO01740.1 - 0.056 13.1 0.0 0.29 10.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 ETO01740.1 - 0.091 13.5 0.0 0.29 11.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 ETO01740.1 - 0.095 12.6 0.3 0.19 11.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 ETO01740.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter RuvA_C PF07499.8 ETO01742.1 - 0.061 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 RuvA, C-terminal domain zf-C3HC4_2 PF13923.1 ETO01744.1 - 0.011 15.6 10.7 0.024 14.6 7.4 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO01744.1 - 0.028 14.0 12.5 0.061 13.0 8.8 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO01744.1 - 0.24 11.0 10.4 0.47 10.1 7.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO01744.1 - 2.1 8.2 14.1 12 5.8 10.0 2.0 1 1 1 2 2 2 0 Ring finger domain zf-RING_5 PF14634.1 ETO01744.1 - 3.9 7.2 13.8 15 5.4 9.6 2.0 1 1 0 1 1 1 0 zinc-RING finger domain Ion_trans PF00520.26 ETO01745.1 - 1.8e-06 27.3 5.1 2.4e-06 26.9 3.5 1.3 1 0 0 1 1 1 1 Ion transport protein Kelch_6 PF13964.1 ETO01746.1 - 6.5e-06 26.0 6.2 0.012 15.7 0.1 3.6 3 1 1 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO01746.1 - 0.00013 21.9 0.2 0.26 11.5 0.0 3.8 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO01746.1 - 0.0019 17.6 3.6 4.1 7.0 0.2 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 ETO01746.1 - 0.012 15.6 4.1 4.8 7.2 1.6 3.5 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.1 ETO01746.1 - 0.013 15.2 0.5 0.53 10.0 0.0 3.4 3 1 0 3 3 3 0 Galactose oxidase, central domain Tmemb_9 PF05434.6 ETO01746.1 - 0.014 15.1 1.3 0.03 14.0 0.9 1.5 1 0 0 1 1 1 0 TMEM9 PDR_CDR PF06422.7 ETO01746.1 - 0.052 13.2 0.8 0.27 10.9 0.1 2.2 2 0 0 2 2 2 0 CDR ABC transporter DUF4245 PF14030.1 ETO01746.1 - 0.082 12.6 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) OAD_gamma PF04277.8 ETO01746.1 - 0.085 13.2 1.1 0.15 12.4 0.8 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Adaptin_N PF01602.15 ETO01747.1 - 1.2e-09 37.0 0.2 5.4e-07 28.3 0.0 2.3 2 0 0 2 2 2 2 Adaptin N terminal region Adeno_hexon PF01065.14 ETO01748.1 - 0.041 12.7 0.1 0.056 12.2 0.1 1.1 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, N-terminal domain FAINT PF04385.10 ETO01748.1 - 0.089 12.6 1.8 0.17 11.7 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function, DUF529 Lip_A_acyltrans PF03279.8 ETO01748.1 - 0.12 11.1 0.0 0.45 9.3 0.0 1.8 2 0 0 2 2 2 0 Bacterial lipid A biosynthesis acyltransferase VWA_2 PF13519.1 ETO01749.1 - 2.9e-05 24.2 0.0 4.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF87 PF01935.12 ETO01749.1 - 0.053 13.3 4.3 0.42 10.3 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF87 HEAT_2 PF13646.1 ETO01750.1 - 3.5e-38 129.7 11.4 6.2e-10 39.2 0.0 6.1 1 1 7 8 8 8 8 HEAT repeats HEAT PF02985.17 ETO01750.1 - 1.4e-20 71.4 2.4 0.084 13.0 0.0 9.9 9 0 0 9 9 9 5 HEAT repeat HEAT_EZ PF13513.1 ETO01750.1 - 1.1e-12 47.9 16.1 0.0078 16.6 0.1 9.7 5 2 5 10 10 10 5 HEAT-like repeat Adaptin_N PF01602.15 ETO01750.1 - 7.4e-12 44.3 16.1 0.0031 15.9 2.5 4.4 2 1 2 4 4 4 4 Adaptin N terminal region HEAT_PBS PF03130.11 ETO01750.1 - 7.7e-05 22.7 7.6 7.6 7.3 0.0 7.2 7 0 0 7 7 7 2 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.2 ETO01750.1 - 0.0013 19.0 0.3 14 6.1 0.0 4.7 3 1 1 4 4 4 1 Vacuolar 14 Fab1-binding region Arm PF00514.18 ETO01750.1 - 0.017 14.8 5.6 0.91 9.4 0.0 5.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat LRR_6 PF13516.1 ETO01750.1 - 0.65 10.2 7.9 8.2 6.8 0.1 4.9 5 0 0 5 5 5 0 Leucine Rich repeat DUF294 PF03445.8 ETO01751.1 - 6.4e-09 35.5 0.1 3.1e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 Putative nucleotidyltransferase DUF294 NTP_transf_2 PF01909.18 ETO01751.1 - 0.007 16.6 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF294_C PF10335.4 ETO01751.1 - 0.098 12.3 0.1 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain HycH PF07450.6 ETO01751.1 - 0.12 12.4 0.1 0.32 11.1 0.0 1.8 2 0 0 2 2 2 0 Formate hydrogenlyase maturation protein HycH Ank_4 PF13637.1 ETO01752.1 - 4e-18 65.4 0.6 1.8e-06 28.2 0.2 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO01752.1 - 1.9e-13 50.5 0.2 2.3e-12 47.0 0.1 2.3 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO01752.1 - 3.4e-13 48.4 0.1 1.3e-07 31.1 0.1 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 ETO01752.1 - 2.4e-12 46.6 0.4 2.6e-08 33.8 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 ETO01752.1 - 6.4e-09 35.1 0.1 8.6e-07 28.4 0.1 3.1 3 0 0 3 3 3 1 Ankyrin repeat DUF2153 PF09921.4 ETO01752.1 - 0.06 12.9 0.0 0.26 10.9 0.0 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) Ras PF00071.17 ETO01755.1 - 5.5e-21 74.6 0.8 2.7e-19 69.1 0.4 2.9 1 1 1 2 2 2 1 Ras family Peptidase_C14 PF00656.17 ETO01755.1 - 1e-09 38.4 0.9 1e-09 38.4 0.6 2.2 3 1 0 3 3 3 1 Caspase domain Miro PF08477.8 ETO01755.1 - 1.4e-06 28.7 3.2 1.6e-05 25.3 0.0 3.9 2 2 3 5 5 5 1 Miro-like protein MULE PF10551.4 ETO01755.1 - 0.017 15.2 0.7 2.3 8.4 0.0 4.1 4 0 0 4 4 4 0 MULE transposase domain AAA_22 PF13401.1 ETO01755.1 - 0.059 13.5 0.5 2.6 8.1 0.0 3.6 3 1 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.20 ETO01755.1 - 0.099 12.1 0.1 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_assoc_C PF09821.4 ETO01755.1 - 0.27 11.5 5.2 5.7 7.2 0.1 3.7 4 0 0 4 4 4 0 C-terminal AAA-associated domain Kelch_1 PF01344.20 ETO01756.1 - 3.7e-07 29.5 0.3 0.00036 20.0 0.1 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO01756.1 - 5.1e-05 22.8 6.0 0.0072 16.0 0.2 4.1 4 1 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 ETO01756.1 - 0.00023 21.1 3.5 0.29 11.3 0.2 4.2 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO01756.1 - 0.002 17.8 1.9 0.35 10.6 0.1 3.5 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO01756.1 - 0.013 15.4 2.4 1.2 9.2 0.1 3.4 4 0 0 4 4 4 0 Kelch motif Allantoicase PF03561.10 ETO01757.1 - 1.2 8.5 4.2 0.63 9.5 0.0 2.5 3 0 0 3 3 3 0 Allantoicase repeat Ribosomal_S4e PF00900.15 ETO01758.1 - 9.6e-26 89.2 0.2 4.8e-25 87.0 0.0 2.3 2 0 0 2 2 2 1 Ribosomal family S4e S4 PF01479.20 ETO01758.1 - 1e-05 24.8 0.5 3e-05 23.3 0.1 2.1 2 0 0 2 2 2 1 S4 domain KOW PF00467.24 ETO01758.1 - 0.0029 17.2 3.3 0.0029 17.2 2.3 2.3 2 0 0 2 2 2 1 KOW motif PPTA PF01239.17 ETO01759.1 - 4.3e-36 120.7 7.3 1.9e-10 39.5 0.2 4.3 4 0 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat TPR_16 PF13432.1 ETO01759.1 - 0.0043 17.6 0.2 0.2 12.3 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO01759.1 - 0.028 14.7 0.9 9.3 6.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat AAT PF03417.11 ETO01760.1 - 1.4e-20 73.6 0.0 2.7e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Lipoprotein_10 PF03202.8 ETO01761.1 - 0.0066 16.4 2.9 0.0083 16.1 2.0 1.1 1 0 0 1 1 1 1 Putative mycoplasma lipoprotein, C-terminal region PIN_4 PF13638.1 ETO01761.1 - 0.077 13.1 1.6 0.088 12.9 1.1 1.2 1 0 0 1 1 1 0 PIN domain GCD14 PF08704.5 ETO01761.1 - 0.11 11.9 1.8 0.12 11.8 1.2 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Orthopox_B11R PF07033.6 ETO01761.1 - 0.2 11.1 4.7 0.37 10.2 3.2 1.5 1 0 0 1 1 1 0 Orthopoxvirus B11R protein Geminin PF07412.7 ETO01761.1 - 2.7 7.6 10.5 12 5.5 7.0 2.0 1 1 1 2 2 2 0 Geminin Myb_DNA-bind_6 PF13921.1 ETO01762.1 - 0.00054 20.0 2.1 0.002 18.1 1.5 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Chromo PF00385.19 ETO01762.1 - 0.013 15.1 1.6 0.22 11.2 0.2 2.9 1 1 1 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain TFIIF_alpha PF05793.7 ETO01763.1 - 3.1 6.0 16.1 3.5 5.8 11.2 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TPR_12 PF13424.1 ETO01764.1 - 8.4e-89 291.6 28.6 2.9e-23 81.5 0.5 5.9 2 2 4 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETO01764.1 - 7.2e-45 148.8 38.7 2.6e-08 33.1 0.5 9.1 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.1 ETO01764.1 - 2.1e-41 139.4 21.9 3.8e-11 42.4 3.7 5.8 3 2 1 5 5 5 5 TPR repeat TPR_2 PF07719.12 ETO01764.1 - 1.2e-36 121.6 28.6 7.7e-06 25.4 0.3 9.1 8 1 1 9 9 9 8 Tetratricopeptide repeat TPR_10 PF13374.1 ETO01764.1 - 1.1e-35 120.5 0.0 1.2e-06 28.2 0.0 8.2 7 1 1 8 8 8 6 Tetratricopeptide repeat TPR_7 PF13176.1 ETO01764.1 - 1.7e-35 117.9 17.7 7.2e-06 25.4 0.1 8.1 7 1 1 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.1 ETO01764.1 - 4.8e-29 97.9 41.0 2e-06 27.1 0.6 8.7 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_17 PF13431.1 ETO01764.1 - 1e-13 50.2 10.6 1 9.6 0.0 8.8 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO01764.1 - 1.5e-12 47.8 0.0 0.09 13.4 0.0 5.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO01764.1 - 9.3e-12 44.4 0.0 0.21 12.3 0.0 7.0 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO01764.1 - 2e-09 37.2 2.1 0.68 10.5 0.0 7.7 9 0 0 9 9 8 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO01764.1 - 1.9e-06 27.0 2.7 0.71 9.1 0.0 6.0 6 0 0 6 6 6 1 SHNi-TPR TPR_19 PF14559.1 ETO01764.1 - 2.3e-06 27.8 5.3 0.38 11.1 1.0 4.8 3 1 2 5 5 5 2 Tetratricopeptide repeat DUF3856 PF12968.2 ETO01764.1 - 0.0028 17.4 0.7 0.16 11.7 0.0 3.0 2 1 0 2 2 2 1 Domain of Unknown Function (DUF3856) MIT PF04212.13 ETO01764.1 - 0.011 15.6 29.0 0.013 15.3 0.2 7.5 8 1 1 9 9 8 0 MIT (microtubule interacting and transport) domain Sel1 PF08238.7 ETO01764.1 - 0.024 15.2 13.0 1.2 9.8 0.1 5.7 6 0 0 6 6 5 0 Sel1 repeat DUF3316 PF11777.3 ETO01764.1 - 0.031 14.0 0.5 1 9.1 0.0 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3316) DUF2225 PF09986.4 ETO01764.1 - 0.092 12.1 20.0 7.3 5.9 4.1 4.3 2 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) Mob_Pre PF01076.14 ETO01764.1 - 0.79 9.3 18.3 0.05 13.2 0.4 3.8 2 1 0 3 3 3 0 Plasmid recombination enzyme TPR_3 PF07720.7 ETO01764.1 - 1.2 8.9 18.6 1.1 9.1 0.4 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO01764.1 - 3 7.7 20.5 16 5.4 0.1 7.1 8 0 0 8 8 8 0 Fis1 C-terminal tetratricopeptide repeat PPR PF01535.15 ETO01764.1 - 4.5 7.4 7.5 10 6.3 0.0 5.3 7 0 0 7 7 5 0 PPR repeat KNOX2 PF03791.8 ETO01765.1 - 0.0059 15.8 0.4 0.016 14.4 0.1 1.8 2 0 0 2 2 2 1 KNOX2 domain Fe_bilin_red PF05996.7 ETO01765.1 - 0.057 12.8 0.0 0.068 12.6 0.0 1.1 1 0 0 1 1 1 0 Ferredoxin-dependent bilin reductase DUF479 PF04336.7 ETO01766.1 - 0.00095 19.2 1.1 0.0035 17.4 0.1 1.9 1 1 1 2 2 2 1 Protein of unknown function, DUF479 DUF4061 PF13270.1 ETO01766.1 - 0.042 13.9 0.4 0.042 13.9 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) DUF1423 PF07227.6 ETO01766.1 - 0.7 8.4 13.4 0.13 10.8 4.0 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1423) TINF2_N PF14973.1 ETO01767.1 - 0.071 13.2 2.0 0.09 12.9 1.4 1.2 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus DUF4467 PF14729.1 ETO01767.1 - 0.22 11.8 4.0 0.39 11.0 2.8 1.5 1 1 0 1 1 1 0 Domain of unknown function with cystatin-like fold (DUF4467) BAG PF02179.11 ETO01767.1 - 0.81 9.8 5.3 10 6.2 3.7 2.2 1 1 0 1 1 1 0 BAG domain PDEase_I PF00233.14 ETO01768.1 - 3.5e-30 105.5 4.0 6e-30 104.7 2.8 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF2457 PF10446.4 ETO01768.1 - 0.044 12.5 6.7 0.072 11.8 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 ETO01768.1 - 0.18 9.8 3.7 0.24 9.4 2.5 1.2 1 0 0 1 1 1 0 CDC45-like protein PBP_sp32 PF07222.7 ETO01768.1 - 1.1 8.4 9.5 5 6.2 0.1 2.3 2 0 0 2 2 2 0 Proacrosin binding protein sp32 NOA36 PF06524.7 ETO01768.1 - 2.1 7.5 7.0 3.1 6.9 4.9 1.2 1 0 0 1 1 1 0 NOA36 protein Tom22 PF04281.8 ETO01768.1 - 3.4 7.1 8.1 0.48 9.9 2.8 1.6 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 BSP_II PF05432.6 ETO01768.1 - 5.8 6.0 13.9 23 4.1 9.6 1.8 1 1 0 1 1 1 0 Bone sialoprotein II (BSP-II) ANAPC15 PF15243.1 ETO01769.1 - 0.067 13.2 2.5 0.35 10.9 1.7 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 15 VPS11_C PF12451.3 ETO01769.1 - 0.36 10.7 1.7 1.1 9.1 0.0 2.4 2 1 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal DUF2847 PF11009.3 ETO01770.1 - 0.022 14.3 0.1 0.043 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) DUF3092 PF11289.3 ETO01772.1 - 0.0046 16.2 0.1 0.0099 15.1 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3092) Phage_tube PF04985.9 ETO01773.1 - 1.6 8.1 5.4 0.36 10.2 0.4 2.2 2 1 0 2 2 2 0 Phage tail tube protein FII Atx10homo_assoc PF09759.4 ETO01774.1 - 0.012 15.3 0.1 0.014 15.1 0.1 1.1 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain eIF3_N PF09440.5 ETO01774.1 - 0.091 12.9 0.3 0.12 12.5 0.2 1.2 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain Arm PF00514.18 ETO01777.1 - 0.0013 18.5 0.0 0.022 14.5 0.0 2.8 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat DUF4280 PF14107.1 ETO01777.1 - 0.052 13.8 0.3 0.32 11.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4280) V-ATPase_H_C PF11698.3 ETO01777.1 - 0.095 12.6 0.0 0.095 12.6 0.0 3.4 3 2 1 4 4 4 0 V-ATPase subunit H ABC2_membrane PF01061.19 ETO01778.1 - 8.5e-17 61.0 38.0 1.3e-14 53.8 11.7 2.1 1 1 1 2 2 2 2 ABC-2 type transporter PDR_CDR PF06422.7 ETO01778.1 - 8 6.1 7.7 0.67 9.6 0.1 2.7 2 0 0 2 2 2 0 CDR ABC transporter Phage_tube PF04985.9 ETO01779.1 - 0.14 11.5 0.0 0.28 10.6 0.0 1.6 2 0 0 2 2 2 0 Phage tail tube protein FII TMF_TATA_bd PF12325.3 ETO01780.1 - 0.0048 16.6 0.8 0.0088 15.7 0.5 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding RNA_pol_Rpb2_2 PF04561.9 ETO01780.1 - 0.0081 15.5 0.7 0.011 15.1 0.5 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 Kelch_6 PF13964.1 ETO01781.1 - 0.006 16.7 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 Kelch motif Kelch_5 PF13854.1 ETO01781.1 - 0.021 14.7 0.0 6.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Kelch motif Kelch_1 PF01344.20 ETO01781.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Kelch motif MSV199 PF10553.4 ETO01783.1 - 3.3 7.6 16.0 8.2 6.3 11.1 1.7 1 1 0 1 1 1 0 MSV199 domain Kelch_4 PF13418.1 ETO01784.1 - 1e-06 28.3 0.1 0.00019 21.1 0.0 2.6 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO01784.1 - 4.1e-06 26.3 1.7 0.00094 18.8 0.3 2.7 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO01784.1 - 5.1e-05 23.2 1.4 0.0037 17.3 0.5 2.6 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.20 ETO01784.1 - 5.5e-05 22.6 0.9 5.5e-05 22.6 0.6 2.3 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.1 ETO01784.1 - 0.0042 17.0 0.3 0.12 12.3 0.5 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO01784.1 - 0.0062 16.6 0.0 0.037 14.1 0.0 2.2 2 0 0 2 2 2 1 Galactose oxidase, central domain BRF1 PF07741.8 ETO01786.1 - 0.022 14.9 0.4 0.052 13.7 0.3 1.6 1 0 0 1 1 1 0 Brf1-like TBP-binding domain PSD4 PF07631.6 ETO01787.1 - 0.1 12.9 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1592) Ribosomal_S8e PF01201.17 ETO01787.1 - 0.15 12.2 0.5 0.19 11.8 0.4 1.3 1 1 0 1 1 1 0 Ribosomal protein S8e ATP13 PF12921.2 ETO01790.1 - 0.028 13.7 3.1 0.052 12.9 0.2 2.4 2 0 0 2 2 2 0 Mitochondrial ATPase expression Ribosomal_L19e PF01280.15 ETO01791.1 - 0.072 12.8 1.2 0.2 11.4 0.2 2.0 2 0 0 2 2 2 0 Ribosomal protein L19e DUF3445 PF11927.3 ETO01792.1 - 0.031 13.6 0.4 0.034 13.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3445) Cystatin PF00031.16 ETO01792.1 - 0.059 13.4 3.0 0.78 9.9 0.3 2.3 2 0 0 2 2 2 0 Cystatin domain CPG4 PF15481.1 ETO01792.1 - 0.087 13.1 1.5 0.2 12.0 1.1 1.6 1 0 0 1 1 1 0 Chondroitin proteoglycan 4 Kelch_4 PF13418.1 ETO01793.1 - 3.8e-05 23.3 0.0 0.00095 18.8 0.0 2.3 1 1 1 2 2 2 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO01793.1 - 0.001 19.2 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO01793.1 - 0.0022 18.0 0.0 0.029 14.5 0.0 2.4 1 1 1 2 2 2 1 Kelch motif Kelch_2 PF07646.10 ETO01793.1 - 0.034 13.9 0.1 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 Kelch motif DUF1735 PF08522.5 ETO01793.1 - 0.088 13.2 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1735) GGDEF PF00990.16 ETO01794.1 - 0.0046 16.5 0.2 0.0097 15.4 0.0 1.6 2 0 0 2 2 2 1 GGDEF domain Nop25 PF09805.4 ETO01795.1 - 0.11 12.5 6.3 0.12 12.3 4.3 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Pyridox_oxase_2 PF12766.2 ETO01795.1 - 0.17 12.2 1.0 0.22 11.8 0.7 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Vmethyltransf_C PF08456.5 ETO01795.1 - 0.85 8.9 5.0 0.93 8.8 3.5 1.0 1 0 0 1 1 1 0 Viral methyltransferase C-terminal DUF3513 PF12026.3 ETO01795.1 - 1.1 8.7 5.3 1.2 8.6 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) Sec62 PF03839.11 ETO01795.1 - 4.5 6.6 7.0 5.6 6.3 4.8 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF1168 PF06658.7 ETO01795.1 - 5.3 6.5 12.8 6.7 6.2 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) PRE_C2HC PF07530.6 ETO01796.1 - 0.5 10.2 5.4 0.65 9.9 0.1 3.2 4 0 0 4 4 4 0 Associated with zinc fingers DUF2626 PF11117.3 ETO01797.1 - 0.099 13.0 1.1 0.18 12.2 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2626) YopJ PF03421.11 ETO01798.1 - 0.075 12.8 0.4 0.13 12.0 0.0 1.6 2 0 0 2 2 2 0 YopJ Serine/Threonine acetyltransferase U-box PF04564.10 ETO01799.1 - 2e-13 50.0 1.0 9.1e-13 47.9 0.0 2.7 2 1 0 2 2 2 1 U-box domain DUF4570 PF15134.1 ETO01799.1 - 0.26 11.1 3.7 0.27 11.0 1.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4570) SR-25 PF10500.4 ETO01800.1 - 0.2 11.0 7.5 0.24 10.8 5.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MFMR PF07777.6 ETO01800.1 - 0.55 10.1 15.3 0.73 9.7 10.6 1.1 1 0 0 1 1 1 0 G-box binding protein MFMR DUF3694 PF12473.3 ETO01800.1 - 0.89 9.2 7.6 1.2 8.7 5.3 1.2 1 0 0 1 1 1 0 Kinesin protein FAM60A PF15396.1 ETO01800.1 - 2.6 7.7 11.5 3 7.5 8.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Pollen_allerg_2 PF01620.11 ETO01800.1 - 4.1 7.7 7.0 5.1 7.3 4.8 1.2 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) Tis11B_N PF04553.7 ETO01800.1 - 4.2 7.6 13.8 0.14 12.3 4.4 2.0 1 1 1 2 2 2 0 Tis11B like protein, N terminus Plasmid_parti PF01672.11 ETO01800.1 - 10 6.6 8.3 16 6.0 1.0 2.3 2 0 0 2 2 2 0 Putative plasmid partition protein WD40 PF00400.27 ETO01801.1 - 1.6e-53 176.7 23.5 1.1e-11 44.1 0.5 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO01801.1 - 2.5e-09 35.8 3.2 0.0031 15.7 0.0 4.4 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Ank_2 PF12796.2 ETO01802.1 - 7.7e-14 51.7 0.5 7.7e-14 51.7 0.3 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO01802.1 - 8.9e-10 37.8 0.5 0.00016 21.2 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 ETO01802.1 - 1.8e-09 36.9 0.2 0.00061 19.7 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 ETO01802.1 - 2.5e-09 37.4 0.2 5.7e-07 29.8 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO01802.1 - 0.00025 21.1 7.6 0.092 13.0 0.0 3.8 2 1 2 4 4 4 2 Ankyrin repeats (many copies) WD40 PF00400.27 ETO01803.1 - 7.7e-57 187.2 21.5 3.1e-11 42.7 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO01803.1 - 1.1e-11 43.5 1.1 0.0031 15.6 0.1 4.6 1 1 3 5 5 5 4 Nucleoporin Nup120/160 OKR_DC_1_N PF03709.10 ETO01806.1 - 0.07 13.1 0.0 2 8.4 0.0 2.2 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain Pex14_N PF04695.8 ETO01807.1 - 0.063 13.3 1.1 0.063 13.3 0.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_C14 PF00656.17 ETO01809.1 - 1.4e-11 44.5 0.3 2.4e-11 43.7 0.2 1.3 1 0 0 1 1 1 1 Caspase domain Kelch_6 PF13964.1 ETO01809.1 - 5.1e-07 29.5 1.6 0.0022 18.0 0.0 4.1 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO01809.1 - 8.4e-05 22.2 1.1 0.31 10.8 0.1 3.8 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO01809.1 - 0.00013 21.8 1.6 0.0078 16.1 0.0 3.7 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.20 ETO01809.1 - 0.0025 17.3 1.2 0.099 12.2 0.0 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 ETO01809.1 - 0.0044 17.1 0.2 0.031 14.4 0.0 2.5 3 0 0 3 3 3 1 Galactose oxidase, central domain DUF2636 PF11120.3 ETO01809.1 - 0.03 13.8 0.7 0.081 12.4 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2636) Kelch_2 PF07646.10 ETO01809.1 - 0.16 11.7 1.0 2 8.3 0.1 3.1 3 0 0 3 3 3 0 Kelch motif Cys_knot PF00007.17 ETO01810.1 - 0.19 11.7 5.3 0.29 11.2 3.7 1.4 1 0 0 1 1 1 0 Cystine-knot domain zf-MIZ PF02891.15 ETO01810.1 - 0.46 10.0 5.5 0.32 10.5 1.6 2.3 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-CCHC_6 PF15288.1 ETO01810.1 - 1.3 8.8 4.7 1.2 8.9 0.1 2.9 3 1 1 4 4 4 0 Zinc knuckle zf-C3HC4_2 PF13923.1 ETO01810.1 - 2.9 7.9 8.6 1 9.4 1.4 3.2 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) PP2C PF00481.16 ETO01811.1 - 1.5e-09 37.6 0.0 2.5e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 ETO01811.1 - 0.084 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) DUF2040 PF09745.4 ETO01812.1 - 4.4e-19 68.5 20.0 4.4e-19 68.5 13.8 3.5 3 1 0 3 3 3 3 Coiled-coil domain-containing protein 55 (DUF2040) EABR PF12180.3 ETO01813.1 - 0.081 12.2 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 Patched PF02460.13 ETO01814.1 - 0.0033 15.4 1.1 0.0045 14.9 0.8 1.2 1 0 0 1 1 1 1 Patched family Pex16 PF08610.5 ETO01814.1 - 0.25 10.2 17.3 0.35 9.8 12.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) LMBR1 PF04791.11 ETO01814.1 - 2.1 6.8 15.7 5.5 5.4 10.9 1.6 1 1 0 1 1 1 0 LMBR1-like membrane protein TraG_N PF07916.6 ETO01814.1 - 4.9 5.4 14.9 8.7 4.6 10.3 1.4 1 0 0 1 1 1 0 TraG-like protein, N-terminal region TMEM51 PF15345.1 ETO01815.1 - 0.14 11.7 2.5 0.17 11.5 1.8 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 ATP11 PF06644.6 ETO01815.1 - 2.3 7.6 5.9 3 7.2 4.1 1.1 1 0 0 1 1 1 0 ATP11 protein Peptidase_C14 PF00656.17 ETO01816.1 - 1.5e-10 41.1 1.4 3e-10 40.2 1.0 1.5 1 1 0 1 1 1 1 Caspase domain TFIIS_M PF07500.9 ETO01817.1 - 0.011 15.8 2.9 0.011 15.7 0.7 1.9 1 1 1 2 2 2 0 Transcription factor S-II (TFIIS), central domain zf-C3HC4_3 PF13920.1 ETO01820.1 - 1.1e-14 53.8 10.6 1.8e-14 53.1 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO01820.1 - 0.00031 20.6 14.8 0.00058 19.8 10.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 ETO01820.1 - 0.00044 19.7 6.1 0.0009 18.7 4.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.1 ETO01820.1 - 0.0018 17.9 13.4 0.0035 17.0 9.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 ETO01820.1 - 0.067 13.0 14.1 0.12 12.2 9.8 1.4 1 0 0 1 1 1 0 Ring finger domain DUF4492 PF14899.1 ETO01820.1 - 0.16 11.4 3.9 0.28 10.7 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4492) DUF2457 PF10446.4 ETO01820.1 - 0.26 9.9 5.9 0.41 9.3 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CS PF04969.11 ETO01821.1 - 2.2e-06 28.1 0.3 2.2e-06 28.1 0.2 2.1 3 0 0 3 3 3 1 CS domain Peptidase_M50B PF13398.1 ETO01822.1 - 2.2 7.6 15.8 2.4 7.5 11.0 1.2 1 0 0 1 1 1 0 Peptidase M50B-like WD40 PF00400.27 ETO01823.1 - 4.8e-28 95.9 10.3 1.3e-10 40.7 0.4 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO01823.1 - 5.3e-08 31.4 2.1 8.5e-06 24.1 0.5 2.3 1 1 0 2 2 2 2 Nucleoporin Nup120/160 NOA36 PF06524.7 ETO01825.1 - 7.7 5.6 8.5 24 4.0 2.6 2.3 2 0 0 2 2 2 0 NOA36 protein Nudix_N_2 PF14803.1 ETO01826.1 - 0.1 12.3 0.2 0.1 12.3 0.1 2.3 2 0 0 2 2 2 0 Nudix N-terminal FTH PF01827.22 ETO01829.1 - 0.076 12.6 0.2 0.17 11.4 0.1 1.6 1 1 0 1 1 1 0 FTH domain MAM PF00629.18 ETO01830.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 MAM domain DUF3294 PF07957.6 ETO01831.1 - 0.015 14.8 1.9 0.018 14.6 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) OmpH PF03938.9 ETO01831.1 - 0.027 14.4 1.5 0.22 11.4 0.3 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DrrA_P4M PF14860.1 ETO01831.1 - 0.15 11.8 3.0 0.16 11.6 1.1 1.7 1 1 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain Peptidase_M1 PF01433.15 ETO01832.1 - 5.9e-50 170.4 0.8 1.5e-37 129.6 0.0 2.4 1 1 1 2 2 2 2 Peptidase family M1 DUF3700 PF12481.3 ETO01833.1 - 0.015 14.5 1.5 0.017 14.3 1.0 1.0 1 0 0 1 1 1 0 Aluminium induced protein CHORD PF04968.7 ETO01833.1 - 0.25 11.6 1.8 0.31 11.3 0.1 1.9 2 0 0 2 2 2 0 CHORD RAMP PF04901.8 ETO01833.1 - 0.26 11.0 4.9 0.48 10.1 0.4 2.1 1 1 1 2 2 2 0 Receptor activity modifying family DUF302 PF03625.9 ETO01834.1 - 0.063 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF302 CHORD PF04968.7 ETO01834.1 - 0.079 13.2 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 CHORD DUF4555 PF15093.1 ETO01835.1 - 0.1 11.4 0.1 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4555) WD40 PF00400.27 ETO01836.1 - 1.9e-16 59.2 3.9 2.1e-10 40.0 0.2 3.5 3 1 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO01836.1 - 0.0021 16.3 0.1 0.34 9.0 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO01836.1 - 0.0026 16.5 0.8 0.028 13.1 0.5 2.0 1 1 0 1 1 1 1 Nup133 N terminal like DUF1837 PF08878.6 ETO01837.1 - 0.13 11.7 9.6 0.24 10.9 6.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1837) DUF3561 PF12084.3 ETO01838.1 - 0.26 11.1 0.0 0.26 11.1 0.0 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF3561) DUF373 PF04123.8 ETO01838.1 - 2.1 7.3 6.6 3.7 6.4 4.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Hydrolase PF00702.21 ETO01839.1 - 9.3e-05 22.9 0.0 0.00012 22.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 ETO01839.1 - 0.012 15.1 2.4 0.02 14.4 1.7 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Phage_gp53 PF11246.3 ETO01839.1 - 0.039 13.3 0.1 0.053 12.9 0.1 1.4 1 1 0 1 1 1 0 Base plate wedge protein 53 Hydrolase_like2 PF13246.1 ETO01839.1 - 0.093 12.6 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit WD40 PF00400.27 ETO01840.1 - 8.8e-104 336.0 21.8 1.3e-14 53.4 0.0 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat PQQ_2 PF13360.1 ETO01840.1 - 1.3e-09 37.9 2.9 6.7e-05 22.4 0.5 4.3 1 1 1 2 2 2 2 PQQ-like domain Gmad1 PF10647.4 ETO01840.1 - 2.4e-09 36.9 0.1 0.012 15.0 0.0 4.4 3 1 1 4 4 4 2 Lipoprotein LpqB beta-propeller domain Cytochrom_D1 PF02239.11 ETO01840.1 - 0.00026 19.3 4.9 0.26 9.5 0.1 3.9 1 1 2 4 4 4 2 Cytochrome D1 heme domain PD40 PF07676.7 ETO01840.1 - 0.00042 19.9 17.8 9.1 6.0 0.0 7.5 8 0 0 8 8 8 1 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 ETO01840.1 - 0.0011 18.1 0.0 14 4.6 0.0 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1258) Rpn3_C PF08375.6 ETO01840.1 - 0.0017 18.6 0.2 20 5.7 0.0 5.1 5 0 0 5 5 5 0 Proteasome regulatory subunit C-terminal NYD-SP28_assoc PF14775.1 ETO01840.1 - 0.0033 17.0 4.5 61 3.4 0.0 6.1 7 0 0 7 7 7 0 Sperm tail C-terminal domain Pentapeptide PF00805.17 ETO01840.1 - 0.0074 15.5 0.1 0.021 14.0 0.1 1.7 1 1 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 ETO01840.1 - 0.022 14.6 0.0 0.055 13.3 0.0 1.7 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) DUF3292 PF11696.3 ETO01840.1 - 0.053 11.3 2.3 0.077 10.8 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Proteasome_A_N PF10584.4 ETO01840.1 - 0.63 9.4 19.5 16 4.9 0.0 7.1 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature Peptidase_M1 PF01433.15 ETO01841.1 - 2.9e-06 26.6 0.0 3.3e-06 26.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M1 WD40 PF00400.27 ETO01842.1 - 2e-12 46.4 1.5 2.2e-11 43.1 0.1 2.8 3 0 0 3 3 3 1 WD domain, G-beta repeat Calcyon PF06387.6 ETO01843.1 - 0.025 13.9 0.4 0.034 13.5 0.3 1.2 1 0 0 1 1 1 0 D1 dopamine receptor-interacting protein (calcyon) PAP_assoc PF03828.14 ETO01844.1 - 8.6e-10 38.4 1.3 3.2e-09 36.5 0.1 2.6 2 1 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 ETO01844.1 - 3.3e-05 24.1 0.0 0.00012 22.3 0.0 2.0 1 0 0 1 1 1 1 Nucleotidyltransferase domain ETRAMP PF09716.5 ETO01844.1 - 0.0026 17.6 0.3 1.7 8.6 0.0 3.1 2 1 0 2 2 2 2 Malarial early transcribed membrane protein (ETRAMP) PAP_central PF04928.12 ETO01844.1 - 0.0053 15.6 0.2 2.3 6.9 0.0 2.4 2 0 0 2 2 2 2 Poly(A) polymerase central domain zf-C3HC4_3 PF13920.1 ETO01845.1 - 8e-09 35.0 8.8 1.3e-08 34.3 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO01845.1 - 1.7e-06 27.9 10.8 3.3e-06 27.0 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO01845.1 - 1.3e-05 24.8 9.7 2.7e-05 23.7 6.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 ETO01845.1 - 3.6e-05 23.5 6.3 0.00013 21.8 4.4 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 ETO01845.1 - 0.00011 21.7 9.8 0.00026 20.5 6.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO01845.1 - 0.0037 17.0 10.8 0.012 15.4 7.6 1.8 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 ETO01845.1 - 0.0077 15.9 7.6 0.034 13.8 5.3 2.2 1 0 0 1 1 1 1 RING-type zinc-finger DUF1192 PF06698.6 ETO01845.1 - 0.033 14.0 2.0 2 8.3 0.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) Prok-RING_4 PF14447.1 ETO01845.1 - 0.074 12.6 5.0 0.18 11.4 3.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 CPSase_L_D3 PF02787.14 ETO01845.1 - 0.11 12.2 6.1 0.98 9.2 0.3 2.6 3 0 0 3 3 3 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain zf-RING_6 PF14835.1 ETO01845.1 - 0.42 10.4 4.2 1 9.2 2.9 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 ETO01845.1 - 1.5 8.4 11.5 1.4 8.5 3.1 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain TPR_12 PF13424.1 ETO01846.1 - 6.1e-102 333.7 46.1 3.2e-20 71.8 0.4 6.1 3 1 4 7 7 7 7 Tetratricopeptide repeat TPR_11 PF13414.1 ETO01846.1 - 9e-55 182.2 55.8 1e-15 57.1 0.8 7.1 5 3 1 6 6 6 5 TPR repeat TPR_1 PF00515.23 ETO01846.1 - 1e-51 170.4 75.7 1.1e-07 31.1 0.1 10.5 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_10 PF13374.1 ETO01846.1 - 1.1e-45 152.2 5.2 5.9e-06 26.0 0.0 10.3 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.12 ETO01846.1 - 3.6e-45 148.2 54.4 2e-05 24.1 0.3 10.4 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_7 PF13176.1 ETO01846.1 - 3.6e-35 116.9 20.1 0.00013 21.5 0.1 11.0 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_8 PF13181.1 ETO01846.1 - 3.8e-30 101.3 73.1 8.2e-06 25.2 1.0 11.3 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_16 PF13432.1 ETO01846.1 - 1.3e-18 67.1 11.8 0.00064 20.3 0.0 6.4 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 ETO01846.1 - 2.7e-17 61.7 0.1 5 8.0 0.0 9.1 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO01846.1 - 8.6e-17 59.8 34.6 0.0031 17.6 0.2 9.8 9 1 0 9 9 8 6 Tetratricopeptide repeat TPR_6 PF13174.1 ETO01846.1 - 9e-16 57.1 16.5 0.045 14.2 0.0 10.0 10 0 0 10 10 9 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO01846.1 - 5.2e-13 48.9 31.7 3.8e-05 23.7 2.9 6.4 4 2 3 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO01846.1 - 2.7e-08 34.0 13.0 0.011 15.9 0.1 6.0 6 1 0 6 6 5 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO01846.1 - 1.8e-06 27.0 6.5 2.7 7.2 0.0 7.0 7 0 0 7 7 7 1 SHNi-TPR DUF2225 PF09986.4 ETO01846.1 - 3.9e-06 26.4 39.1 0.0011 18.4 0.5 6.6 1 1 4 6 6 6 3 Uncharacterized protein conserved in bacteria (DUF2225) zf-TRAF PF02176.13 ETO01846.1 - 6.1e-05 23.3 1.2 6.1e-05 23.3 0.8 2.0 2 0 0 2 2 1 1 TRAF-type zinc finger TPR_5 PF12688.2 ETO01846.1 - 0.00012 22.1 0.0 9.3 6.3 0.0 4.1 2 1 1 3 3 3 0 Tetratrico peptide repeat PPR PF01535.15 ETO01846.1 - 0.00098 18.9 8.8 16 5.7 0.0 7.3 8 0 0 8 8 8 0 PPR repeat RPN7 PF10602.4 ETO01846.1 - 0.0015 17.9 0.7 0.0015 17.9 0.5 6.1 4 4 3 7 7 7 1 26S proteasome subunit RPN7 MIT PF04212.13 ETO01846.1 - 0.012 15.4 38.9 0.44 10.4 0.1 9.4 8 2 1 9 9 9 0 MIT (microtubule interacting and transport) domain Rdx PF10262.4 ETO01846.1 - 0.077 13.0 2.6 1.4 9.0 0.0 3.7 3 1 0 3 3 2 0 Rdx family TPR_3 PF07720.7 ETO01846.1 - 0.29 10.9 41.8 0.2 11.4 4.6 6.9 7 0 0 7 7 6 0 Tetratricopeptide repeat Sel1 PF08238.7 ETO01846.1 - 9.6 6.9 0.0 9.6 6.9 0.0 7.5 9 0 0 9 9 8 0 Sel1 repeat TPR_12 PF13424.1 ETO01848.1 - 2.9e-117 382.7 11.9 3.7e-27 94.0 0.1 5.1 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETO01848.1 - 2.3e-65 214.8 0.0 8.3e-10 38.2 0.0 7.7 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_7 PF13176.1 ETO01848.1 - 1.3e-58 190.2 10.7 2.5e-08 33.0 0.0 7.2 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.23 ETO01848.1 - 1.1e-54 179.9 38.8 9.7e-10 37.6 0.2 7.3 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_11 PF13414.1 ETO01848.1 - 7.5e-54 179.2 18.1 1.8e-17 62.7 0.3 4.5 3 1 0 4 4 4 4 TPR repeat TPR_2 PF07719.12 ETO01848.1 - 7e-46 150.4 21.8 2.8e-07 29.9 0.1 7.3 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_8 PF13181.1 ETO01848.1 - 1e-40 134.4 48.6 9.3e-10 37.5 1.5 7.3 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_17 PF13431.1 ETO01848.1 - 1.9e-30 102.5 17.6 0.0012 18.9 0.5 8.5 8 1 0 8 8 8 7 Tetratricopeptide repeat TPR_16 PF13432.1 ETO01848.1 - 2.9e-19 69.2 0.0 0.00028 21.4 0.0 6.1 1 1 6 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO01848.1 - 5.1e-17 60.8 0.0 0.11 13.1 0.0 7.1 5 1 2 7 7 7 4 Tetratricopeptide repeat PPR PF01535.15 ETO01848.1 - 2.2e-16 58.5 19.4 0.098 12.6 0.1 7.3 7 0 0 7 7 7 6 PPR repeat TPR_6 PF13174.1 ETO01848.1 - 5.5e-14 51.5 2.8 0.26 11.8 0.0 7.0 7 0 0 7 7 6 3 Tetratricopeptide repeat SNAP PF14938.1 ETO01848.1 - 8.5e-12 44.7 15.6 1.7e-05 24.1 3.6 4.3 1 1 1 3 3 3 3 Soluble NSF attachment protein, SNAP Apc3 PF12895.2 ETO01848.1 - 1.5e-11 44.3 16.7 9.6e-06 25.6 2.4 3.9 1 1 4 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO01848.1 - 2.2e-11 43.9 1.3 0.17 12.2 0.1 5.6 2 2 4 6 6 6 4 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO01848.1 - 4e-09 35.5 0.5 0.5 9.6 0.0 6.2 6 0 0 6 6 6 1 SHNi-TPR MIT PF04212.13 ETO01848.1 - 6e-09 35.6 20.5 0.27 11.1 0.2 6.4 6 0 0 6 6 6 4 MIT (microtubule interacting and transport) domain Sel1 PF08238.7 ETO01848.1 - 1.1e-07 32.2 12.0 0.89 10.2 0.1 6.7 7 0 0 7 7 7 2 Sel1 repeat TPR_3 PF07720.7 ETO01848.1 - 1.7e-07 30.8 21.4 0.45 10.3 0.2 6.7 7 0 0 7 7 6 3 Tetratricopeptide repeat DUF627 PF04781.7 ETO01848.1 - 4.6e-07 29.4 13.4 1.2 8.7 0.0 6.2 2 1 5 7 7 7 3 Protein of unknown function (DUF627) Ten1_2 PF15490.1 ETO01848.1 - 4.9e-06 26.1 0.0 3.3 7.3 0.0 5.0 1 1 5 6 6 6 1 Telomere-capping, CST complex subunit TPR_21 PF09976.4 ETO01848.1 - 8.3e-06 25.8 5.0 0.056 13.3 0.0 4.9 3 2 2 5 5 5 2 Tetratricopeptide repeat RPN7 PF10602.4 ETO01848.1 - 2.1e-05 24.0 12.6 1.3 8.4 0.8 5.5 3 1 2 5 5 5 1 26S proteasome subunit RPN7 PPR_2 PF13041.1 ETO01848.1 - 3.1e-05 23.8 9.7 13 5.8 0.1 6.7 7 0 0 7 7 7 0 PPR repeat family DUF3568 PF12092.3 ETO01848.1 - 0.0001 21.9 0.3 5.2 6.7 0.0 4.6 2 1 3 6 6 6 0 Protein of unknown function (DUF3568) Pep3_Vps18 PF05131.9 ETO01848.1 - 0.0017 17.7 8.1 4.5 6.6 0.1 6.1 7 0 0 7 7 7 0 Pep3/Vps18/deep orange family TPR_5 PF12688.2 ETO01848.1 - 0.0024 17.8 0.5 23 5.0 0.0 4.4 4 1 1 5 5 5 0 Tetratrico peptide repeat Sipho_tail PF05709.6 ETO01848.1 - 0.0031 16.6 0.6 0.33 10.0 0.0 2.9 3 0 0 3 3 3 1 Phage tail protein DUF494 PF04361.8 ETO01848.1 - 0.04 13.6 0.3 8.4 6.0 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF494) Clathrin PF00637.15 ETO01848.1 - 0.06 12.9 18.3 1.3 8.6 0.8 6.1 4 2 2 6 6 6 0 Region in Clathrin and VPS Mob_Pre PF01076.14 ETO01848.1 - 0.086 12.4 8.0 15 5.1 0.2 3.9 2 1 3 5 5 5 0 Plasmid recombination enzyme FATC PF02260.15 ETO01848.1 - 0.25 10.7 8.6 32 4.0 0.3 4.4 4 0 0 4 4 4 0 FATC domain Mad3_BUB1_I PF08311.7 ETO01848.1 - 0.26 11.0 11.6 13 5.5 0.0 5.8 7 1 0 7 7 6 0 Mad3/BUB1 homology region 1 ATP-synt_E_2 PF08112.6 ETO01848.1 - 1.7 8.7 17.8 4.7 7.3 0.2 5.9 6 0 0 6 6 6 0 ATP synthase epsilon subunit Ubiq-assoc PF09145.5 ETO01848.1 - 4.7 7.1 13.0 35 4.3 0.1 5.3 6 0 0 6 6 5 0 Ubiquitin-associated Geminin PF07412.7 ETO01849.1 - 0.00094 18.9 2.3 0.00094 18.9 1.6 2.2 2 0 0 2 2 2 1 Geminin Tnp_P_element PF12017.3 ETO01849.1 - 0.034 13.3 6.4 0.53 9.4 0.3 2.0 2 0 0 2 2 2 0 Transposase protein DUF641 PF04859.7 ETO01849.1 - 0.058 13.1 10.8 0.81 9.4 0.8 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) NQR2_RnfD_RnfE PF03116.10 ETO01849.1 - 0.061 12.5 0.0 0.069 12.3 0.0 1.1 1 0 0 1 1 1 0 NQR2, RnfD, RnfE family DivIC PF04977.10 ETO01849.1 - 0.071 12.6 0.4 0.071 12.6 0.3 2.9 2 1 1 3 3 3 0 Septum formation initiator MHC2-interact PF09307.5 ETO01849.1 - 0.08 12.7 1.3 11 5.8 0.0 2.2 1 1 1 2 2 2 0 CLIP, MHC2 interacting GAS PF13851.1 ETO01849.1 - 0.12 11.5 11.6 0.088 11.9 2.6 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4200 PF13863.1 ETO01849.1 - 0.12 12.3 12.9 0.31 11.0 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Tup_N PF08581.5 ETO01849.1 - 0.15 12.2 9.6 0.68 10.1 1.4 2.5 2 1 0 2 2 2 0 Tup N-terminal DUF1640 PF07798.6 ETO01849.1 - 0.27 11.2 9.2 0.15 12.1 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) DUF4140 PF13600.1 ETO01849.1 - 0.39 11.2 4.2 10 6.6 0.1 2.2 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TMF_TATA_bd PF12325.3 ETO01849.1 - 0.4 10.4 8.2 1.8 8.2 0.1 2.3 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Lzipper-MIP1 PF14389.1 ETO01849.1 - 0.43 10.7 8.1 0.12 12.4 2.3 1.9 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Bap31 PF05529.7 ETO01849.1 - 0.47 9.8 14.1 1.4 8.3 2.6 2.1 1 1 0 2 2 2 0 B-cell receptor-associated protein 31-like Mnd1 PF03962.10 ETO01849.1 - 0.56 9.8 8.5 0.68 9.5 0.2 2.1 2 0 0 2 2 2 0 Mnd1 family DUF3573 PF12097.3 ETO01849.1 - 1.2 7.7 3.9 1.2 7.6 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) ubiquitin PF00240.18 ETO01849.1 - 1.2 8.5 4.9 1.3 8.4 0.1 2.5 2 1 0 2 2 2 0 Ubiquitin family HOOK PF05622.7 ETO01849.1 - 1.3 6.7 12.1 1.6 6.4 4.1 1.5 1 1 1 2 2 2 0 HOOK protein TMF_DNA_bd PF12329.3 ETO01849.1 - 1.6 8.5 18.1 0.92 9.3 2.2 2.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Seryl_tRNA_N PF02403.17 ETO01849.1 - 1.7 8.6 9.7 1.1 9.3 1.1 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF2681 PF10883.3 ETO01849.1 - 3.5 7.8 12.1 2.4 8.3 0.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) OmpH PF03938.9 ETO01849.1 - 4.3 7.2 9.3 7.8 6.4 6.4 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) bZIP_1 PF00170.16 ETO01849.1 - 6.6 6.7 14.0 4.7 7.2 0.5 3.0 2 1 1 3 3 3 0 bZIP transcription factor Cep57_CLD_2 PF14197.1 ETO01849.1 - 6.9 6.6 10.5 58 3.7 0.1 3.0 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 FlaC_arch PF05377.6 ETO01849.1 - 8.9 6.2 8.3 3.4 7.6 1.0 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) zf-C3HC4_2 PF13923.1 ETO01850.1 - 1.4 9.0 10.4 0.28 11.2 1.7 3.1 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO01850.1 - 4.6 7.1 6.5 1.8 8.4 2.3 2.0 2 1 0 2 2 2 0 Ring finger domain CNH PF00780.17 ETO01851.1 - 0.0023 17.3 0.4 0.38 10.1 0.0 2.7 2 1 0 2 2 2 2 CNH domain BBS2_N PF14781.1 ETO01851.1 - 0.0053 16.3 0.2 0.047 13.3 0.0 2.6 3 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, N-terminal PQQ_3 PF13570.1 ETO01851.1 - 0.0075 16.5 1.4 3.4 8.0 0.1 3.7 3 0 0 3 3 3 1 PQQ-like domain DNA_pol_E_B PF04042.11 ETO01852.1 - 0.098 11.8 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B ERAP1_C PF11838.3 ETO01854.1 - 7.9e-15 54.9 0.0 1.7e-14 53.8 0.0 1.5 1 1 0 1 1 1 1 ERAP1-like C-terminal domain Xan_ur_permease PF00860.15 ETO01855.1 - 7.8e-23 80.5 42.5 1e-22 80.1 29.5 1.1 1 0 0 1 1 1 1 Permease family Kelch_2 PF07646.10 ETO01856.1 - 0.017 14.8 0.0 0.38 10.5 0.0 3.1 4 0 0 4 4 4 0 Kelch motif DUF4097 PF13349.1 ETO01856.1 - 0.02 14.4 6.7 0.42 10.1 0.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4097) WD40 PF00400.27 ETO01857.1 - 3.1e-33 112.4 0.2 1.1e-08 34.6 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat PD40 PF07676.7 ETO01857.1 - 8.5e-05 22.1 0.1 0.67 9.6 0.0 4.1 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO01857.1 - 0.00038 18.8 0.0 0.0035 15.6 0.0 2.0 2 0 0 2 2 2 1 Cytochrome D1 heme domain eIF2A PF08662.6 ETO01857.1 - 0.0057 16.3 0.0 0.27 10.9 0.0 2.6 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO01857.1 - 0.026 12.6 0.1 2.4 6.1 0.0 2.3 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Proteasome_A_N PF10584.4 ETO01857.1 - 0.044 13.1 0.9 13 5.2 0.0 4.0 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature MRJP PF03022.11 ETO01857.1 - 0.046 12.9 0.1 2.9 7.0 0.0 2.6 1 1 1 3 3 3 0 Major royal jelly protein Resistin PF06954.6 ETO01857.1 - 0.12 12.6 0.0 23 5.3 0.0 3.1 3 1 0 3 3 3 0 Resistin Nop53 PF07767.6 ETO01858.1 - 0.38 9.6 46.2 0.55 9.1 32.1 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Ebp2 PF05890.7 ETO01858.1 - 1.4 8.2 45.9 2.1 7.6 31.8 1.2 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 DUF572 PF04502.8 ETO01858.1 - 1.4 8.0 42.1 1.7 7.7 29.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) MIP-T3 PF10243.4 ETO01858.1 - 3.4 6.0 63.7 4.4 5.6 44.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ino80_Iec3 PF14612.1 ETO01859.1 - 0.22 11.5 0.6 0.24 11.4 0.4 1.2 1 0 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling Pkr1 PF08636.5 ETO01859.1 - 1.4 9.0 4.8 0.37 10.8 1.5 1.4 2 0 0 2 2 2 0 ER protein Pkr1 WD40 PF00400.27 ETO01860.1 - 2.2e-23 81.2 7.6 1.1e-08 34.6 0.0 4.4 4 1 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO01860.1 - 1.7e-05 23.2 0.3 0.048 11.7 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 AAA_5 PF07728.9 ETO01861.1 - 0.002 17.8 0.0 0.0038 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.10 ETO01861.1 - 0.12 11.0 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Kinase-PPPase PF03618.9 ETO01861.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Kinase/pyrophosphorylase AAA PF00004.24 ETO01861.1 - 0.12 12.5 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ste50p-SAM PF09235.5 ETO01865.1 - 0.0084 16.1 0.1 0.012 15.6 0.1 1.4 1 1 0 1 1 1 1 Ste50p, sterile alpha motif Toxin_R_bind_N PF07953.7 ETO01865.1 - 0.0095 15.4 0.8 0.012 15.1 0.5 1.1 1 0 0 1 1 1 1 Clostridium neurotoxin, N-terminal receptor binding Kelch_6 PF13964.1 ETO01866.1 - 0.00091 19.3 0.0 0.0032 17.5 0.0 1.9 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.1 ETO01866.1 - 0.009 15.9 0.3 0.016 15.1 0.2 1.3 1 0 0 1 1 1 1 Kelch motif Kelch_1 PF01344.20 ETO01866.1 - 0.014 14.8 0.1 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Kelch motif Kelch_2 PF07646.10 ETO01866.1 - 0.091 12.5 0.2 0.39 10.5 0.1 2.0 2 0 0 2 2 2 0 Kelch motif Tetraspannin PF00335.15 ETO01868.1 - 1.6 7.9 7.0 2.3 7.4 4.0 1.8 1 1 1 2 2 2 0 Tetraspanin family Tubulin PF00091.20 ETO01869.1 - 2.5e-62 210.5 0.0 3e-62 210.2 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.1 ETO01869.1 - 0.0014 17.6 0.0 0.0019 17.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin like Misat_Tub_SegII PF10644.4 ETO01869.1 - 0.017 15.1 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain RED_C PF07807.6 ETO01873.1 - 0.023 14.8 0.1 0.074 13.2 0.0 1.8 2 0 0 2 2 2 0 RED-like protein C-terminal region AAA PF00004.24 ETO01874.1 - 5.1e-10 39.6 0.0 0.00049 20.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETO01874.1 - 7.2e-08 32.2 0.1 0.00044 19.9 0.0 3.8 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETO01874.1 - 1.5e-06 28.3 0.0 0.059 13.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 ETO01874.1 - 6.2e-05 22.8 0.5 0.0065 16.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 ETO01874.1 - 0.00022 21.2 0.1 0.039 13.9 0.0 3.1 2 1 0 3 3 3 1 AAA ATPase domain ABC_tran PF00005.22 ETO01874.1 - 0.00028 21.1 0.0 0.0015 18.7 0.0 2.2 2 0 0 2 2 2 1 ABC transporter Arch_ATPase PF01637.13 ETO01874.1 - 0.00033 20.4 0.7 0.056 13.1 0.0 3.1 3 0 0 3 3 3 1 Archaeal ATPase Viral_helicase1 PF01443.13 ETO01874.1 - 0.00068 19.2 0.1 0.02 14.4 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF258 PF03193.11 ETO01874.1 - 0.0013 17.8 0.0 0.004 16.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 ETO01874.1 - 0.0021 17.5 0.1 0.014 14.8 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 ETO01874.1 - 0.0044 15.9 0.0 0.014 14.3 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.9 ETO01874.1 - 0.0057 16.5 0.0 0.15 11.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 ETO01874.1 - 0.0087 15.4 0.0 1.5 8.1 0.0 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_18 PF13238.1 ETO01874.1 - 0.011 16.0 0.1 0.13 12.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain Sigma54_activ_2 PF14532.1 ETO01874.1 - 0.013 15.5 0.0 0.49 10.4 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain MCM PF00493.18 ETO01874.1 - 0.021 13.6 2.2 0.46 9.2 0.0 3.5 4 0 0 4 4 4 0 MCM2/3/5 family Mg_chelatase PF01078.16 ETO01874.1 - 0.04 13.0 0.4 5 6.2 0.0 3.3 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 ETO01874.1 - 0.054 12.9 0.1 1.7 8.0 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain RNA_helicase PF00910.17 ETO01874.1 - 0.058 13.5 0.2 2 8.6 0.0 3.2 4 0 0 4 4 2 0 RNA helicase Miro PF08477.8 ETO01874.1 - 0.066 13.7 0.0 0.28 11.6 0.0 2.2 1 0 0 1 1 1 0 Miro-like protein AAA_17 PF13207.1 ETO01874.1 - 0.1 13.4 0.5 0.69 10.7 0.3 2.7 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 ETO01874.1 - 0.12 11.2 0.1 1 8.1 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.7 ETO01874.1 - 0.22 11.1 1.7 0.63 9.6 0.1 2.6 3 1 0 3 3 2 0 NACHT domain AAA_23 PF13476.1 ETO01874.1 - 0.93 9.7 7.4 14 5.9 5.1 2.9 1 1 0 1 1 1 0 AAA domain DUF1168 PF06658.7 ETO01875.1 - 8.7 5.8 16.5 9.6 5.7 11.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Alpha-amylase PF00128.19 ETO01876.1 - 0.03 13.7 0.2 0.035 13.5 0.1 1.0 1 0 0 1 1 1 0 Alpha amylase, catalytic domain WD40 PF00400.27 ETO01877.1 - 2.1e-23 81.2 10.5 2.2e-11 43.1 0.6 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO01877.1 - 1.7e-06 26.4 2.3 0.00031 19.0 0.3 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO01877.1 - 0.23 10.7 6.0 0.27 10.5 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4221) UN_NPL4 PF11543.3 ETO01879.1 - 0.053 13.8 0.1 0.19 12.0 0.0 2.0 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 Kelch_1 PF01344.20 ETO01880.1 - 2.1e-05 23.9 5.9 0.0033 16.9 0.4 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 ETO01880.1 - 0.00056 19.8 1.0 0.0067 16.3 0.2 2.9 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 ETO01880.1 - 0.0015 18.6 4.6 1.7 8.9 0.1 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO01880.1 - 0.0023 18.0 0.5 0.045 13.9 0.0 2.8 3 0 0 3 3 3 1 Galactose oxidase, central domain RNA_pol_3_Rpc31 PF11705.3 ETO01880.1 - 0.0064 16.4 8.3 0.0064 16.4 5.8 2.0 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 Kelch_4 PF13418.1 ETO01880.1 - 0.011 15.5 0.9 0.13 12.0 0.2 2.6 2 0 0 2 2 2 0 Galactose oxidase, central domain Nucleoplasmin PF03066.10 ETO01880.1 - 0.41 10.1 10.1 0.78 9.2 7.0 1.5 1 0 0 1 1 1 0 Nucleoplasmin BSP_II PF05432.6 ETO01880.1 - 0.6 9.3 15.9 0.99 8.6 11.0 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Kelch_2 PF07646.10 ETO01880.1 - 0.87 9.4 3.8 17 5.4 0.3 3.2 3 0 0 3 3 3 0 Kelch motif FAM176 PF14851.1 ETO01880.1 - 1.7 8.3 8.3 3.1 7.4 5.8 1.4 1 0 0 1 1 1 0 FAM176 family Pox_Ag35 PF03286.9 ETO01880.1 - 1.8 8.0 12.7 3.6 7.0 8.8 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PBP_sp32 PF07222.7 ETO01880.1 - 8.2 5.5 11.7 17 4.4 8.1 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Neuregulin PF02158.10 ETO01881.1 - 0.23 10.1 2.7 0.1 11.3 0.2 1.5 1 1 0 1 1 1 0 Neuregulin family GlcNAc PF11397.3 ETO01882.1 - 1.6e-10 40.6 0.0 2.5e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) zf-HC5HC2H_2 PF13832.1 ETO01882.1 - 0.0021 18.0 2.4 0.27 11.2 0.2 2.4 1 1 1 2 2 2 2 PHD-zinc-finger like domain TPR_12 PF13424.1 ETO01884.1 - 1.4e-74 246.0 3.5 1.1e-26 92.5 0.0 3.7 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO01884.1 - 3.4e-31 106.2 0.0 2.8e-11 42.9 0.0 4.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO01884.1 - 6.1e-25 85.0 2.4 1.6e-08 33.6 0.0 3.8 5 0 0 5 5 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO01884.1 - 6.5e-24 82.5 14.6 1e-08 34.3 0.1 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO01884.1 - 4.7e-23 80.6 7.0 2e-13 49.7 0.3 3.0 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.1 ETO01884.1 - 4.8e-19 66.6 12.1 2.1e-06 27.1 0.4 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO01884.1 - 5.6e-18 63.3 4.6 1.3e-05 24.6 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO01884.1 - 8.2e-15 53.6 1.6 0.0011 18.9 0.0 4.8 3 1 2 5 5 5 3 Tetratricopeptide repeat MIT PF04212.13 ETO01884.1 - 7.1e-08 32.2 3.0 0.017 14.9 0.0 3.3 4 0 0 4 4 3 2 MIT (microtubule interacting and transport) domain TPR_16 PF13432.1 ETO01884.1 - 1.2e-07 32.1 0.0 0.0075 16.9 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO01884.1 - 3.5e-06 27.0 1.7 0.016 15.2 0.2 2.7 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETO01884.1 - 4.3e-06 26.8 0.2 2.6 8.7 0.0 4.1 3 2 0 3 3 3 1 Tetratricopeptide repeat DUF627 PF04781.7 ETO01884.1 - 6e-06 25.8 0.0 0.47 10.1 0.0 3.1 1 1 2 3 3 3 2 Protein of unknown function (DUF627) TPR_14 PF13428.1 ETO01884.1 - 2.3e-05 24.5 0.0 2.5 8.9 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO01884.1 - 0.00013 22.2 0.0 0.032 14.5 0.0 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat PPR PF01535.15 ETO01884.1 - 0.00045 20.0 1.2 0.18 11.8 0.0 3.2 3 0 0 3 3 3 1 PPR repeat TPR_3 PF07720.7 ETO01884.1 - 0.0022 17.7 6.9 3.4 7.5 0.1 3.9 4 1 0 4 4 4 2 Tetratricopeptide repeat DUF2225 PF09986.4 ETO01884.1 - 0.0064 15.9 0.2 2.1 7.7 0.0 2.0 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) SNAP PF14938.1 ETO01884.1 - 0.0072 15.4 0.0 1.5 7.9 0.0 2.0 1 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP DUF3568 PF12092.3 ETO01884.1 - 0.0075 15.9 0.0 2.8 7.6 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3568) Fis1_TPR_C PF14853.1 ETO01884.1 - 0.0084 15.9 1.0 10 6.1 0.0 3.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat KH_4 PF13083.1 ETO01884.1 - 0.011 15.3 0.0 0.076 12.6 0.0 2.2 1 1 1 2 2 2 0 KH domain Pep3_Vps18 PF05131.9 ETO01884.1 - 0.017 14.5 0.2 8.3 5.8 0.0 2.9 3 0 0 3 3 3 0 Pep3/Vps18/deep orange family P22_AR_C PF10548.4 ETO01884.1 - 0.023 14.5 0.5 9.2 6.2 0.0 2.9 3 0 0 3 3 3 0 P22AR C-terminal domain Musclin PF11037.3 ETO01884.1 - 0.031 13.8 0.0 20 4.7 0.0 2.9 3 0 0 3 3 3 0 Insulin-resistance promoting peptide in skeletal muscle Rab5-bind PF09311.6 ETO01884.1 - 0.09 12.6 0.0 0.19 11.6 0.0 1.6 1 1 0 1 1 1 0 Rabaptin-like protein MCM PF00493.18 ETO01887.1 - 0.021 13.6 0.0 3.1 6.5 0.0 2.2 2 0 0 2 2 2 0 MCM2/3/5 family Thioredoxin PF00085.15 ETO01887.1 - 0.088 12.4 0.2 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin Pentapeptide PF00805.17 ETO01888.1 - 0.00051 19.2 2.2 0.013 14.7 0.7 2.8 2 1 1 3 3 3 2 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 ETO01888.1 - 0.0011 18.7 0.7 0.0024 17.7 0.5 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.1 ETO01888.1 - 0.0031 17.2 2.6 0.0055 16.4 1.8 1.7 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) WD40 PF00400.27 ETO01889.1 - 3.2e-68 223.3 15.2 6.1e-13 48.1 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO01889.1 - 0.00076 18.3 10.6 0.97 8.0 1.0 4.2 1 1 0 2 2 2 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO01889.1 - 0.0059 14.9 0.6 1.8 6.7 0.1 2.9 2 1 1 3 3 3 2 Cytochrome D1 heme domain HARP PF07443.8 ETO01889.1 - 0.42 10.0 2.0 6.6 6.1 0.0 3.1 4 0 0 4 4 4 0 HepA-related protein (HARP) Choline_transpo PF04515.7 ETO01890.1 - 1.9e-12 46.6 17.3 1.1e-08 34.2 4.9 2.6 1 1 1 3 3 3 2 Plasma-membrane choline transporter DUF2178 PF09946.4 ETO01890.1 - 0.47 10.2 6.4 0.18 11.5 1.9 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2178) GP41 PF00517.12 ETO01890.1 - 1 8.8 3.6 10 5.5 0.3 2.1 2 0 0 2 2 2 0 Retroviral envelope protein WD40 PF00400.27 ETO01893.1 - 0.0012 18.6 1.7 0.0055 16.5 0.1 2.6 2 1 0 2 2 2 1 WD domain, G-beta repeat Cep57_MT_bd PF06657.8 ETO01894.1 - 0.37 10.7 6.3 0.19 11.6 1.5 2.1 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Syntaxin_2 PF14523.1 ETO01894.1 - 1.5 8.9 7.6 1.1 9.2 1.0 2.1 1 1 1 2 2 2 0 Syntaxin-like protein zf-CCHC PF00098.18 ETO01895.1 - 0.0055 16.5 8.4 0.017 15.0 5.8 1.9 1 0 0 1 1 1 1 Zinc knuckle DdrB PF12747.2 ETO01896.1 - 0.038 13.7 0.0 0.44 10.2 0.0 2.1 1 1 1 2 2 2 0 DdrB-like protein Bromodomain PF00439.20 ETO01896.1 - 0.058 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Bromodomain LMF1 PF06762.9 ETO01897.1 - 0.006 15.4 0.0 0.0063 15.3 0.0 1.0 1 0 0 1 1 1 1 Lipase maturation factor Rax2 PF12768.2 ETO01897.1 - 0.02 14.0 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF3262 PF11660.3 ETO01897.1 - 0.058 13.5 0.2 0.078 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) HTH_Tnp_Tc3_2 PF01498.13 ETO01898.1 - 2.8e-11 43.3 0.5 4.2e-11 42.7 0.3 1.3 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.1 ETO01898.1 - 0.00083 19.3 0.0 0.0034 17.3 0.0 2.0 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.1 ETO01898.1 - 0.0061 16.7 0.0 0.096 12.8 0.0 2.4 2 1 1 3 3 3 1 Winged helix-turn helix HTH_23 PF13384.1 ETO01898.1 - 0.011 15.3 0.3 0.093 12.4 0.0 2.6 3 0 0 3 3 3 0 Homeodomain-like domain HTH_38 PF13936.1 ETO01898.1 - 0.025 14.1 0.0 0.86 9.2 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 ETO01898.1 - 0.032 14.1 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 Transposase Exo_endo_phos_2 PF14529.1 ETO01899.1 - 5.4e-08 32.4 1.4 2.5e-07 30.3 0.1 2.4 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase HBS1_N PF08938.5 ETO01899.1 - 0.044 13.9 0.1 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 HBS1 N-terminus SLIDE PF09111.5 ETO01899.1 - 0.13 12.0 3.9 0.26 11.0 2.7 1.5 1 0 0 1 1 1 0 SLIDE ALMT PF11744.3 ETO01899.1 - 0.95 8.0 6.2 1.1 7.8 3.9 1.3 1 1 0 1 1 1 0 Aluminium activated malate transporter DUF940 PF06082.6 ETO01899.1 - 2.2 6.7 6.2 2.8 6.3 4.3 1.1 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) Glyco_hydro_88 PF07470.8 ETO01900.1 - 0.005 15.9 0.9 0.0077 15.3 0.7 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 EF-hand_10 PF14788.1 ETO01900.1 - 0.12 12.0 0.5 0.37 10.4 0.1 2.2 2 0 0 2 2 2 0 EF hand NTNH_C PF08470.5 ETO01901.1 - 0.68 9.5 7.6 0.11 12.0 2.1 2.0 1 1 1 2 2 2 0 Nontoxic nonhaemagglutinin C-terminal UPF0449 PF15136.1 ETO01902.1 - 0.2 11.8 1.9 0.24 11.6 0.4 1.7 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 Ank_2 PF12796.2 ETO01903.1 - 1.1e-11 44.9 0.2 1.5e-05 25.2 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO01903.1 - 1.3e-09 38.3 0.1 1e-07 32.2 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO01903.1 - 3.3e-07 29.8 0.2 0.00011 22.1 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.25 ETO01903.1 - 5.5e-06 25.9 0.0 2.7e-05 23.7 0.0 2.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 ETO01903.1 - 1.3e-05 25.2 0.1 0.00012 22.2 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) G-gamma PF00631.17 ETO01903.1 - 0.023 14.4 0.0 0.73 9.6 0.0 2.5 2 0 0 2 2 2 0 GGL domain WD40 PF00400.27 ETO01905.1 - 1.3e-62 205.5 9.2 2.2e-15 55.8 0.0 5.0 5 0 0 5 5 5 5 WD domain, G-beta repeat PQQ_2 PF13360.1 ETO01905.1 - 1.6e-09 37.5 0.5 1.6e-05 24.4 0.1 2.6 1 1 1 2 2 2 2 PQQ-like domain Nup160 PF11715.3 ETO01905.1 - 2e-08 32.8 1.1 0.073 11.1 0.0 3.7 1 1 2 3 3 3 3 Nucleoporin Nup120/160 PD40 PF07676.7 ETO01905.1 - 5.4e-05 22.7 8.3 6.6 6.5 0.0 5.2 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat BBS2_Mid PF14783.1 ETO01905.1 - 6.8e-05 22.6 0.5 2.5 7.8 0.1 4.0 1 1 2 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Cytochrom_D1 PF02239.11 ETO01905.1 - 0.00019 19.8 0.8 0.031 12.5 0.1 2.9 1 1 2 3 3 3 1 Cytochrome D1 heme domain Gmad1 PF10647.4 ETO01905.1 - 0.00027 20.4 0.1 0.013 14.8 0.1 2.5 1 1 1 2 2 2 2 Lipoprotein LpqB beta-propeller domain Nucleoporin_N PF08801.6 ETO01905.1 - 0.00032 19.5 6.1 0.61 8.7 1.0 3.5 1 1 2 3 3 3 3 Nup133 N terminal like DUF3732 PF12532.3 ETO01905.1 - 0.00035 20.1 0.9 2.2 7.7 0.0 3.1 1 1 2 3 3 3 2 Protein of unknown function (DUF3732) DUF3312 PF11768.3 ETO01905.1 - 0.0014 16.9 0.0 0.13 10.4 0.0 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF3312) DUF3601 PF12208.3 ETO01905.1 - 0.0018 18.1 0.0 4.3 7.3 0.0 3.3 1 1 2 3 3 3 1 Domain of unknown function (DUF3601) DUF1258 PF06869.7 ETO01905.1 - 0.004 16.2 0.1 0.75 8.8 0.0 3.0 1 1 2 3 3 3 1 Protein of unknown function (DUF1258) BLUF PF04940.7 ETO01905.1 - 0.01 15.5 0.0 4 7.2 0.0 3.1 3 0 0 3 3 3 0 Sensors of blue-light using FAD Rpn3_C PF08375.6 ETO01905.1 - 0.012 16.0 0.0 0.47 10.8 0.0 2.8 3 0 0 3 3 3 0 Proteasome regulatory subunit C-terminal TolB_N PF04052.8 ETO01905.1 - 0.014 15.4 0.0 57 3.8 0.0 3.9 4 0 0 4 4 4 0 TolB amino-terminal domain NYD-SP28_assoc PF14775.1 ETO01905.1 - 0.033 13.8 0.0 72 3.1 0.0 3.8 4 0 0 4 4 4 0 Sperm tail C-terminal domain PQQ_3 PF13570.1 ETO01905.1 - 0.033 14.4 0.0 16 5.9 0.0 3.4 2 1 2 4 4 4 0 PQQ-like domain Proteasome_A_N PF10584.4 ETO01905.1 - 0.047 13.0 12.1 16 4.8 0.0 5.3 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature WXG100 PF06013.7 ETO01905.1 - 0.079 12.9 0.0 7.5 6.6 0.0 2.9 3 0 0 3 3 3 0 Proteins of 100 residues with WXG PQQ PF01011.16 ETO01905.1 - 0.11 12.1 0.0 26 4.6 0.0 3.5 4 0 0 4 4 4 0 PQQ enzyme repeat Baculo_19 PF04798.7 ETO01906.1 - 0.069 12.5 0.2 0.092 12.1 0.2 1.2 1 0 0 1 1 1 0 Baculovirus 19 kDa protein conserved region Phospholip_B PF04916.8 ETO01907.1 - 5.1e-69 232.8 0.7 6.5e-69 232.4 0.5 1.1 1 0 0 1 1 1 1 Phospholipase B BTV_NS2 PF04514.7 ETO01911.1 - 0.33 9.7 5.9 0.36 9.6 4.1 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF3245 PF11595.3 ETO01911.1 - 0.38 11.0 9.5 0.43 10.8 6.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) GTP1_OBG PF01018.17 ETO01912.1 - 0.0011 18.5 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 GTP1/OBG NACHT PF05729.7 ETO01912.1 - 0.0019 17.9 0.0 0.013 15.1 0.0 2.0 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.17 ETO01912.1 - 0.004 16.0 0.6 1.3 7.8 0.7 2.1 2 0 0 2 2 2 2 NB-ARC domain YodL PF14191.1 ETO01912.1 - 0.88 10.0 6.0 1 9.8 0.4 2.2 2 0 0 2 2 2 0 YodL-like zf-RING_2 PF13639.1 ETO01913.1 - 1.4e-08 34.4 5.5 3.1e-08 33.3 3.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 ETO01913.1 - 2.6e-05 24.2 1.2 5.8e-05 23.1 0.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 ETO01913.1 - 0.00069 19.4 0.9 0.00069 19.4 0.6 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 ETO01913.1 - 0.0011 18.6 4.0 0.0024 17.5 2.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO01913.1 - 0.0015 18.1 4.3 0.0034 17.0 3.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 ETO01913.1 - 0.0039 16.9 0.9 0.0084 15.9 0.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 ETO01913.1 - 0.0079 15.8 5.3 0.027 14.1 3.7 2.0 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 ETO01913.1 - 0.0091 15.9 4.7 0.0091 15.9 3.3 2.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) HalX PF08663.5 ETO01913.1 - 0.37 10.7 6.7 2.4 8.2 0.1 2.9 2 1 1 3 3 3 0 HalX domain TerY-C PF15616.1 ETO01913.1 - 2.1 8.2 7.3 0.89 9.4 3.1 1.8 2 0 0 2 2 2 0 TerY-C metal binding domain zf-RING_2 PF13639.1 ETO01914.1 - 4.7e-09 35.9 9.6 1.2e-08 34.6 6.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO01914.1 - 2.7e-06 27.3 10.2 2.7e-06 27.3 7.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO01914.1 - 3.8e-06 26.4 6.8 3.8e-06 26.4 4.7 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 ETO01914.1 - 7.5e-05 22.3 5.9 7.5e-05 22.3 4.1 2.5 2 0 0 2 2 2 1 PHD-finger zf-RING_5 PF14634.1 ETO01914.1 - 0.00055 19.6 9.4 0.002 17.7 5.1 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 ETO01914.1 - 0.00056 19.9 8.8 0.00056 19.9 6.1 2.4 2 1 1 3 3 3 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 ETO01914.1 - 0.0052 16.6 5.9 0.0052 16.6 4.1 2.4 1 1 1 2 2 1 1 zinc finger of C3HC4-type, RING Nab1 PF04902.7 ETO01914.1 - 0.084 12.3 0.2 0.57 9.6 0.0 2.2 3 0 0 3 3 3 0 Conserved region in Nab1 zf-MIZ PF02891.15 ETO01914.1 - 0.46 10.0 9.4 0.99 8.9 6.5 1.6 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger DZR PF12773.2 ETO01914.1 - 0.85 9.4 9.9 4.6 7.1 1.3 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-Apc11 PF12861.2 ETO01914.1 - 1.1 9.1 13.8 0.067 13.0 5.2 2.3 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 ETO01914.1 - 1.1 8.8 5.1 2.5 7.6 3.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 ETO01914.1 - 4.9 6.9 13.6 0.48 10.1 2.4 2.7 2 1 0 2 2 2 0 RING-type zinc-finger zf-Di19 PF05605.7 ETO01914.1 - 5 7.3 11.7 2.2 8.4 4.7 2.6 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-HC5HC2H PF13771.1 ETO01914.1 - 7.7 6.7 13.3 0.31 11.1 3.7 2.5 2 1 1 3 3 3 0 PHD-like zinc-binding domain SecA_DEAD PF07517.9 ETO01919.1 - 3.1e-09 36.5 0.0 1.2e-08 34.5 0.0 2.1 1 1 0 1 1 1 1 SecA DEAD-like domain Trp_dioxygenase PF03301.8 ETO01919.1 - 0.0099 15.0 0.5 0.024 13.7 0.1 1.8 2 0 0 2 2 2 1 Tryptophan 2,3-dioxygenase WD40 PF00400.27 ETO01922.1 - 6.8e-07 28.9 2.7 1.2e-06 28.1 1.8 1.5 1 0 0 1 1 1 1 WD domain, G-beta repeat DUF1700 PF08006.6 ETO01922.1 - 0.021 14.1 1.0 0.026 13.8 0.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1700) Prion PF00377.13 ETO01922.1 - 0.032 13.9 0.4 0.048 13.3 0.3 1.2 1 0 0 1 1 1 0 Prion/Doppel alpha-helical domain WD40 PF00400.27 ETO01924.1 - 3.3e-12 45.7 3.6 5.8e-10 38.6 0.4 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat CRT10 PF08728.5 ETO01924.1 - 0.014 13.4 0.2 0.015 13.3 0.1 1.1 1 0 0 1 1 1 0 CRT10 Nup160 PF11715.3 ETO01924.1 - 0.023 12.8 0.0 0.027 12.5 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DUF1914 PF08932.5 ETO01924.1 - 0.03 14.3 0.3 2.1 8.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1914) Erf4 PF10256.4 ETO01925.1 - 0.052 13.4 0.1 0.08 12.8 0.1 1.4 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family U5_2-snRNA_bdg PF10597.4 ETO01925.1 - 0.1 12.1 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 U5-snRNA binding site 2 of PrP8 Kelch_6 PF13964.1 ETO01926.1 - 0.0053 16.8 0.1 0.012 15.7 0.1 1.6 1 0 0 1 1 1 1 Kelch motif Kelch_5 PF13854.1 ETO01926.1 - 0.014 15.3 0.0 0.23 11.4 0.0 2.3 2 0 0 2 2 2 0 Kelch motif DUF836 PF05768.9 ETO01927.1 - 0.26 11.5 2.2 1.3 9.2 1.5 1.9 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) ENTH PF01417.15 ETO01928.1 - 0.082 12.7 0.7 0.15 11.9 0.1 1.7 2 1 0 2 2 2 0 ENTH domain VitK2_biosynth PF02621.9 ETO01928.1 - 0.11 11.7 0.1 0.33 10.1 0.0 1.7 2 0 0 2 2 2 0 Menaquinone biosynthesis CbiA PF01656.18 ETO01929.1 - 1.4e-26 93.1 0.1 1.4e-26 93.1 0.0 2.1 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 ETO01929.1 - 3.3e-11 43.3 0.9 2.3e-10 40.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain YhjQ PF06564.7 ETO01929.1 - 1.2e-09 37.9 0.0 2.2e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 YhjQ protein ArsA_ATPase PF02374.10 ETO01929.1 - 7.8e-06 25.1 0.0 6.8e-05 22.0 0.0 2.5 2 0 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 ETO01929.1 - 2.3e-05 23.5 3.7 0.00013 21.1 0.1 2.7 2 1 0 2 2 2 1 ATPase MipZ Phage_T7_Capsid PF05396.6 ETO01929.1 - 0.055 13.6 0.1 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Phage T7 capsid assembly protein ISK_Channel PF02060.10 ETO01930.1 - 0.46 10.0 4.8 1 8.9 0.1 2.9 2 1 1 3 3 3 0 Slow voltage-gated potassium channel APG17 PF04108.7 ETO01931.1 - 0.2 10.4 4.3 4.8 5.8 2.2 2.1 2 0 0 2 2 2 0 Autophagy protein Apg17 WD40 PF00400.27 ETO01933.1 - 8.8e-46 152.2 11.5 1.9e-11 43.3 0.3 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO01933.1 - 1.6e-11 43.0 4.7 8.1e-05 20.9 0.3 4.0 1 1 3 4 4 4 4 Nucleoporin Nup120/160 DUF2361 PF10153.4 ETO01933.1 - 0.11 12.7 2.2 0.21 11.7 0.5 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2361) CDC37_N PF03234.9 ETO01934.1 - 8.4e-05 22.9 4.0 0.00012 22.4 2.8 1.2 1 0 0 1 1 1 1 Cdc37 N terminal kinase binding FemAB PF02388.11 ETO01934.1 - 0.00015 20.5 12.4 0.00021 20.0 1.0 2.0 2 0 0 2 2 2 1 FemAB family DUF4131 PF13567.1 ETO01934.1 - 0.0017 17.8 0.1 0.0029 17.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) DUF3450 PF11932.3 ETO01934.1 - 0.0017 17.6 0.4 0.0017 17.6 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) DUF972 PF06156.8 ETO01934.1 - 0.0024 18.1 15.9 0.11 12.8 5.9 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF972) TMF_TATA_bd PF12325.3 ETO01934.1 - 0.0034 17.1 25.8 0.03 14.0 5.3 2.1 2 0 0 2 2 2 2 TATA element modulatory factor 1 TATA binding Nucleoside_tran PF01733.13 ETO01934.1 - 0.0035 16.5 2.5 0.0035 16.5 1.7 1.7 1 1 1 2 2 2 1 Nucleoside transporter DUF4337 PF14235.1 ETO01934.1 - 0.0051 16.6 2.3 0.0051 16.6 1.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4337) DivIC PF04977.10 ETO01934.1 - 0.0057 16.1 0.1 0.0057 16.1 0.1 3.5 2 2 1 3 3 3 1 Septum formation initiator 7tm_7 PF08395.7 ETO01934.1 - 0.011 14.8 4.6 0.011 14.8 3.2 2.1 2 0 0 2 2 2 0 7tm Chemosensory receptor Atg14 PF10186.4 ETO01934.1 - 0.03 13.2 18.0 0.086 11.7 3.0 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1664 PF07889.7 ETO01934.1 - 0.032 14.0 1.1 0.032 14.0 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2420 PF10336.4 ETO01934.1 - 0.064 12.8 0.6 0.064 12.8 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2420) LMBR1 PF04791.11 ETO01934.1 - 0.065 11.8 0.1 0.065 11.8 0.1 2.0 1 1 1 2 2 2 0 LMBR1-like membrane protein Tmp39 PF10271.4 ETO01934.1 - 0.075 11.6 3.6 0.084 11.5 2.5 1.1 1 0 0 1 1 1 0 Putative transmembrane protein Spc7 PF08317.6 ETO01934.1 - 0.088 11.4 23.3 0.029 13.0 5.2 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein DASH_Duo1 PF08651.5 ETO01934.1 - 0.096 12.2 11.0 0.99 9.0 0.3 3.2 2 2 1 3 3 3 0 DASH complex subunit Duo1 DUF2203 PF09969.4 ETO01934.1 - 0.097 12.8 8.8 2.7 8.2 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) GAS PF13851.1 ETO01934.1 - 0.11 11.7 27.9 0.53 9.4 6.6 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Imm5 PF14423.1 ETO01934.1 - 0.11 12.1 4.8 0.16 11.5 0.2 2.1 2 0 0 2 2 2 0 Immunity protein Imm5 Mnd1 PF03962.10 ETO01934.1 - 0.11 12.1 21.4 0.56 9.8 4.4 2.1 2 0 0 2 2 2 0 Mnd1 family DUF4446 PF14584.1 ETO01934.1 - 0.12 12.2 7.6 0.16 11.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Peptidase_S49_N PF08496.5 ETO01934.1 - 0.12 12.1 6.3 0.84 9.4 0.1 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DegS PF05384.6 ETO01934.1 - 0.12 11.5 13.0 0.34 10.1 3.2 2.3 2 0 0 2 2 2 0 Sensor protein DegS DUF4201 PF13870.1 ETO01934.1 - 0.15 11.4 25.5 0.43 9.9 5.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) AAA_13 PF13166.1 ETO01934.1 - 0.16 10.3 12.3 1 7.7 3.5 2.0 2 0 0 2 2 2 0 AAA domain Syntaxin PF00804.20 ETO01934.1 - 0.18 11.9 17.6 0.12 12.5 4.9 2.2 2 0 0 2 2 2 0 Syntaxin CDO_I PF05995.7 ETO01934.1 - 0.28 10.3 3.0 2.1 7.4 0.5 2.4 2 1 0 2 2 2 0 Cysteine dioxygenase type I DUF948 PF06103.6 ETO01934.1 - 0.31 10.9 10.0 1.5 8.7 1.5 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Tropomyosin_1 PF12718.2 ETO01934.1 - 0.36 10.6 30.9 0.87 9.4 9.3 2.0 2 0 0 2 2 2 0 Tropomyosin like TBPIP PF07106.8 ETO01934.1 - 0.52 9.8 22.2 0.5 9.9 5.4 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) UPF0184 PF03670.8 ETO01934.1 - 0.59 10.3 11.5 3.1 8.0 0.6 2.8 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) ComC PF03047.9 ETO01934.1 - 0.6 9.5 0.1 0.6 9.5 0.1 3.2 4 0 0 4 4 2 0 COMC family Hemerythrin PF01814.18 ETO01934.1 - 0.62 10.2 5.5 5.9 7.0 0.6 2.7 2 1 1 3 3 3 0 Hemerythrin HHE cation binding domain DUF3584 PF12128.3 ETO01934.1 - 0.67 7.2 24.2 0.22 8.7 5.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) FlaC_arch PF05377.6 ETO01934.1 - 0.9 9.4 17.1 1.5 8.7 1.3 3.7 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) COG2 PF06148.6 ETO01934.1 - 1 9.2 16.8 2.4 8.0 2.4 2.6 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 MscS_porin PF12795.2 ETO01934.1 - 1.1 8.5 31.6 1.7 7.8 8.5 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain ApoC-I PF04691.7 ETO01934.1 - 1.5 8.5 9.4 7.7 6.2 0.6 3.2 3 0 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) Kinetocho_Slk19 PF12709.2 ETO01934.1 - 1.6 8.8 22.6 0.16 12.0 1.5 3.6 2 2 2 4 4 4 0 Central kinetochore-associated DUF4279 PF14106.1 ETO01934.1 - 1.7 8.5 5.3 1 9.2 0.3 2.8 2 2 2 4 4 4 0 Domain of unknown function (DUF4279) APG6 PF04111.7 ETO01934.1 - 1.7 7.5 24.2 0.93 8.4 5.6 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 Mod_r PF07200.8 ETO01934.1 - 1.8 8.4 25.3 0.067 13.1 7.2 2.5 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein WEMBL PF05701.6 ETO01934.1 - 1.9 6.8 23.1 1.9 6.8 5.4 2.1 2 0 0 2 2 2 0 Weak chloroplast movement under blue light DUF1395 PF07160.7 ETO01934.1 - 1.9 7.8 12.6 6.9 6.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1395) KLRAQ PF10205.4 ETO01934.1 - 2.1 8.3 24.5 0.43 10.6 6.5 2.6 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein EzrA PF06160.7 ETO01934.1 - 2.2 6.3 18.6 1.3 7.1 4.6 2.2 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA CENP-F_leu_zip PF10473.4 ETO01934.1 - 2.3 8.0 28.5 3.4 7.5 8.5 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GrpE PF01025.14 ETO01934.1 - 2.6 7.5 21.5 0.8 9.2 3.7 2.3 2 0 0 2 2 2 0 GrpE IFT57 PF10498.4 ETO01934.1 - 3.1 6.4 26.1 1.6 7.4 7.3 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF4220 PF13968.1 ETO01934.1 - 3.2 6.7 9.5 0.79 8.7 3.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4220) AAA_23 PF13476.1 ETO01934.1 - 3.6 7.8 20.9 0.079 13.2 3.7 2.1 2 0 0 2 2 2 0 AAA domain Seryl_tRNA_N PF02403.17 ETO01934.1 - 3.8 7.5 21.2 8.6 6.4 3.1 2.9 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Transposase_1 PF01359.13 ETO01934.1 - 3.8 7.3 9.5 5.1 6.9 0.0 3.3 4 0 0 4 4 3 0 Transposase (partial DDE domain) Sec8_exocyst PF04048.9 ETO01934.1 - 4 7.0 16.5 0.39 10.3 2.0 2.7 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain AAA_27 PF13514.1 ETO01934.1 - 4.6 4.7 17.7 2.6 5.5 3.2 2.0 2 0 0 2 2 2 0 AAA domain Spectrin PF00435.16 ETO01934.1 - 4.7 7.5 22.4 0.86 9.9 5.8 2.8 2 1 0 2 2 2 0 Spectrin repeat CCSMST1 PF15013.1 ETO01934.1 - 4.8 7.1 6.8 1.2 9.0 1.5 2.4 1 1 2 3 3 2 0 CCSMST1 family BLOC1_2 PF10046.4 ETO01934.1 - 5.1 7.2 18.1 3.9 7.6 5.1 2.6 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spore_III_AB PF09548.5 ETO01934.1 - 5.2 6.7 14.4 0.24 11.1 3.2 2.3 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) FliJ PF02050.11 ETO01934.1 - 5.4 7.0 33.3 0.47 10.5 5.9 2.9 2 2 0 2 2 2 0 Flagellar FliJ protein HisKA_3 PF07730.8 ETO01934.1 - 5.9 7.3 10.6 4.6 7.6 0.8 2.7 2 1 0 2 2 2 0 Histidine kinase V_ATPase_I PF01496.14 ETO01934.1 - 6.1 4.5 16.3 0.36 8.6 3.9 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF812 PF05667.6 ETO01934.1 - 6.3 5.1 20.7 4.3 5.7 5.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Peptidase_C65 PF10275.4 ETO01934.1 - 6.3 6.0 16.4 0.3 10.4 5.4 2.0 1 1 1 2 2 2 0 Peptidase C65 Otubain DUF3469 PF11952.3 ETO01934.1 - 6.7 6.4 7.0 15 5.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3469) Phage_GP20 PF06810.6 ETO01934.1 - 6.7 6.1 22.0 0.67 9.3 6.9 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 DivIVA PF05103.8 ETO01934.1 - 7.5 6.6 23.8 9.5 6.2 3.0 3.0 2 2 1 3 3 3 0 DivIVA protein Fib_alpha PF08702.5 ETO01934.1 - 7.7 6.6 16.6 7.9 6.6 4.0 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Filament PF00038.16 ETO01934.1 - 8.3 5.7 23.4 5 6.5 4.7 2.1 2 0 0 2 2 2 0 Intermediate filament protein Lyase_8_N PF08124.6 ETO01934.1 - 8.4 5.1 11.3 4.6 6.0 2.0 2.0 2 0 0 2 2 2 0 Polysaccharide lyase family 8, N terminal alpha-helical domain UPF0242 PF06785.6 ETO01934.1 - 8.8 4.8 22.7 1.7 7.2 6.4 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) NTR2 PF15458.1 ETO01934.1 - 9.1 5.4 21.1 1.7 7.7 3.1 2.2 2 0 0 2 2 2 0 Nineteen complex-related protein 2 Exonuc_VII_L PF02601.10 ETO01934.1 - 9.4 5.3 13.1 20 4.2 9.1 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit ETRAMP PF09716.5 ETO01936.1 - 0.00076 19.3 0.6 0.0026 17.6 0.4 1.8 1 1 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) Zip PF02535.17 ETO01936.1 - 0.017 14.1 1.3 0.02 13.9 0.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Mem_trans PF03547.13 ETO01936.1 - 0.022 13.0 0.6 0.029 12.6 0.4 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF1183 PF06682.7 ETO01936.1 - 0.063 12.8 6.4 0.082 12.4 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Hid1 PF12722.2 ETO01936.1 - 0.45 8.1 9.8 0.42 8.2 6.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ctr PF04145.10 ETO01936.1 - 0.81 9.7 4.2 1.9 8.5 2.9 1.7 1 1 0 1 1 1 0 Ctr copper transporter family EVC2_like PF12297.3 ETO01937.1 - 0.078 11.5 0.7 0.098 11.2 0.5 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein ATP-synt_8 PF00895.15 ETO01937.1 - 3 8.1 6.0 1.2 9.3 1.5 2.3 1 1 1 2 2 2 0 ATP synthase protein 8 ETRAMP PF09716.5 ETO01938.1 - 0.0012 18.7 0.0 0.0028 17.5 0.0 1.7 1 1 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) Zip PF02535.17 ETO01938.1 - 0.0028 16.7 0.4 0.0046 16.0 0.2 1.2 1 1 0 1 1 1 1 ZIP Zinc transporter DUF1183 PF06682.7 ETO01938.1 - 0.028 14.0 5.0 0.036 13.6 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Serinc PF03348.10 ETO01938.1 - 0.05 12.3 0.3 0.058 12.0 0.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ctr PF04145.10 ETO01938.1 - 0.083 12.9 0.7 0.16 12.0 0.5 1.5 1 1 0 1 1 1 0 Ctr copper transporter family Sec62 PF03839.11 ETO01938.1 - 0.55 9.5 2.6 0.98 8.7 1.8 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Hid1 PF12722.2 ETO01938.1 - 0.58 7.7 8.3 0.54 7.8 5.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AlaDh_PNT_N PF05222.10 ETO01939.1 - 2.1e-10 40.7 0.0 0.00075 19.5 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, N-terminal domain Saccharop_dh PF03435.13 ETO01939.1 - 0.0014 17.7 0.0 0.0019 17.2 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase PMP22_Claudin PF00822.15 ETO01939.1 - 0.1 12.2 0.1 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Sialidase PF02973.11 ETO01939.1 - 0.14 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Sialidase, N-terminal domain DUF972 PF06156.8 ETO01940.1 - 6.8 7.0 12.3 3.5 8.0 0.4 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Diphtheria_T PF02764.9 ETO01942.1 - 0.36 10.5 2.6 0.38 10.4 0.8 1.8 2 0 0 2 2 2 0 Diphtheria toxin, T domain PPR PF01535.15 ETO01943.1 - 2.9e-05 23.7 1.9 0.056 13.4 0.1 2.9 3 0 0 3 3 3 2 PPR repeat PPR_2 PF13041.1 ETO01943.1 - 0.00011 22.1 1.0 0.0074 16.2 0.2 2.5 1 1 2 3 3 3 3 PPR repeat family DUF3636 PF12331.3 ETO01943.1 - 0.079 12.5 0.1 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3636) PPR_1 PF12854.2 ETO01943.1 - 0.095 12.2 0.9 0.16 11.4 0.1 1.8 2 0 0 2 2 2 0 PPR repeat TRI5 PF06330.6 ETO01944.1 - 0.0028 16.3 0.8 0.0035 16.0 0.5 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) EF_TS PF00889.14 ETO01944.1 - 0.0094 15.3 0.1 0.011 15.0 0.1 1.1 1 0 0 1 1 1 1 Elongation factor TS DUF4553 PF15090.1 ETO01944.1 - 0.02 13.8 0.2 0.025 13.5 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4553) PUB PF09409.5 ETO01944.1 - 0.05 13.3 1.3 0.081 12.6 0.4 1.8 2 0 0 2 2 2 0 PUB domain PCI PF01399.22 ETO01944.1 - 0.12 12.6 1.9 0.42 10.9 0.3 2.2 1 1 1 2 2 2 0 PCI domain DUF2951 PF11166.3 ETO01944.1 - 0.33 10.8 2.4 2.5 7.9 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) DUF1474 PF07342.6 ETO01945.1 - 0.096 12.9 1.8 1.1 9.5 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1474) Pribosyltran_N PF13793.1 ETO01946.1 - 0.035 13.8 0.5 1.6 8.4 0.1 2.3 2 1 0 2 2 2 0 N-terminal domain of ribose phosphate pyrophosphokinase Glyco_hydro_65m PF03632.10 ETO01946.1 - 0.23 10.1 2.3 0.34 9.5 1.6 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65 central catalytic domain MatP PF06303.7 ETO01946.1 - 1.3 8.9 7.3 3.4 7.5 3.4 2.1 1 1 1 2 2 2 0 Organiser of macrodomain of Terminus of chromosome Peptidase_C14 PF00656.17 ETO01947.1 - 2.5e-13 50.3 1.3 5e-13 49.3 0.9 1.5 1 0 0 1 1 1 1 Caspase domain Kelch_5 PF13854.1 ETO01947.1 - 6.6e-06 25.9 2.5 1.4 8.9 0.1 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO01947.1 - 5.6e-05 23.1 7.4 0.64 10.2 0.1 4.9 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO01947.1 - 0.0015 18.2 1.1 0.025 14.3 0.1 2.8 1 1 1 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO01947.1 - 0.0094 15.4 10.5 1.7 8.2 0.3 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO01947.1 - 0.051 13.3 4.6 2.4 8.0 0.2 4.1 4 0 0 4 4 4 0 Kelch motif Kelch_3 PF13415.1 ETO01947.1 - 0.074 13.2 0.1 2 8.6 0.0 2.9 3 0 0 3 3 3 0 Galactose oxidase, central domain B56 PF01603.15 ETO01948.1 - 3.2e-12 45.7 0.8 3.7e-12 45.5 0.6 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) MIP-T3 PF10243.4 ETO01949.1 - 7.9 4.8 27.3 9.9 4.4 18.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Tubulin PF00091.20 ETO01950.1 - 1.9e-21 76.8 0.1 6.1e-21 75.2 0.1 1.8 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO01950.1 - 2.4e-15 56.7 0.1 5.4e-15 55.5 0.1 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Kelch_6 PF13964.1 ETO01951.1 - 1.5e-08 34.4 4.0 0.0016 18.5 0.2 4.2 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 ETO01951.1 - 7.4e-08 31.8 4.7 0.00017 21.0 0.4 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO01951.1 - 1e-06 28.2 5.4 0.0037 16.9 0.3 5.1 5 1 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 ETO01951.1 - 5.1e-05 23.1 3.3 0.1 12.5 0.3 4.8 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.1 ETO01951.1 - 0.00041 20.0 5.0 0.0021 17.7 0.1 3.9 3 1 1 4 4 4 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO01951.1 - 0.0022 18.0 0.7 0.071 13.2 0.0 3.5 4 0 0 4 4 4 1 Galactose oxidase, central domain Methyltransf_11 PF08241.7 ETO01952.1 - 9.6e-16 58.0 0.0 1.1e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETO01952.1 - 4.6e-13 49.3 0.0 5.6e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO01952.1 - 1.4e-11 44.2 0.0 1.5e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO01952.1 - 3.4e-11 43.6 0.0 4.2e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETO01952.1 - 8.6e-11 41.8 0.0 9.7e-11 41.6 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 ETO01952.1 - 8.8e-11 41.5 0.0 1e-10 41.3 0.0 1.0 1 0 0 1 1 1 1 Nodulation protein S (NodS) TehB PF03848.9 ETO01952.1 - 1.1e-10 41.0 0.0 1.2e-10 40.8 0.0 1.0 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_12 PF08242.7 ETO01952.1 - 1.6e-09 38.1 0.0 1.9e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 ETO01952.1 - 7.4e-07 28.6 0.1 8.6e-07 28.4 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_26 PF13659.1 ETO01952.1 - 6.6e-06 26.1 0.0 9.1e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 ETO01952.1 - 0.00011 21.5 0.0 0.00013 21.2 0.0 1.2 1 1 0 1 1 1 1 CheR methyltransferase, SAM binding domain MTS PF05175.9 ETO01952.1 - 0.00011 21.6 0.0 0.00013 21.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 ETO01952.1 - 0.0015 17.7 0.0 0.0016 17.5 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 ETO01952.1 - 0.003 16.6 0.0 0.0037 16.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase tRNA_U5-meth_tr PF05958.6 ETO01952.1 - 0.009 14.7 0.0 0.013 14.2 0.0 1.2 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_4 PF02390.12 ETO01952.1 - 0.035 13.1 0.0 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase MMR_HSR1 PF01926.18 ETO01953.1 - 0.0079 16.1 0.3 0.04 13.8 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase BAR_3_WASP_bdg PF10456.4 ETO01954.1 - 0.0055 15.9 2.0 0.015 14.6 0.8 2.1 2 1 0 2 2 2 1 WASP-binding domain of Sorting nexin protein Phage_int_SAM_1 PF02899.12 ETO01954.1 - 0.041 14.0 0.2 1.4 9.1 0.0 2.5 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain EST1 PF10374.4 ETO01954.1 - 0.045 13.7 0.9 0.045 13.7 0.6 2.5 2 1 0 2 2 2 0 Telomerase activating protein Est1 KxDL PF10241.4 ETO01954.1 - 0.99 9.3 5.1 1.7 8.6 1.0 2.9 2 1 0 2 2 2 0 Uncharacterized conserved protein Kin17_mid PF10357.4 ETO01955.1 - 0.059 13.0 3.9 0.081 12.5 2.7 1.2 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein SR-25 PF10500.4 ETO01955.1 - 0.086 12.2 18.3 0.089 12.2 12.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ART PF01129.13 ETO01957.1 - 0.074 12.1 0.0 0.21 10.6 0.0 1.8 1 1 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase Endonuc-dimeris PF09124.5 ETO01957.1 - 0.26 10.9 2.3 0.64 9.6 1.4 1.8 1 1 0 1 1 1 0 T4 recombination endonuclease VII, dimerisation SCO1-SenC PF02630.9 ETO01959.1 - 3.9e-36 124.2 1.9 7.6e-36 123.3 1.3 1.4 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.1 ETO01959.1 - 0.00033 20.7 0.0 0.00076 19.5 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 ETO01959.1 - 0.00034 20.2 0.0 0.00077 19.1 0.0 1.7 1 0 0 1 1 1 1 AhpC/TSA family Zip PF02535.17 ETO01960.1 - 0.0076 15.3 0.4 0.016 14.2 0.0 1.7 2 0 0 2 2 2 1 ZIP Zinc transporter DUF2615 PF11027.3 ETO01960.1 - 0.008 16.0 0.0 0.038 13.9 0.0 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) FAM176 PF14851.1 ETO01960.1 - 0.063 12.9 1.4 0.19 11.3 0.0 2.1 1 1 1 2 2 2 0 FAM176 family SDA1 PF05285.7 ETO01960.1 - 1 8.5 8.7 1.4 8.1 6.0 1.1 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.4 ETO01960.1 - 5.3 5.6 15.2 6.9 5.2 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF2201_N PF13203.1 ETO01961.1 - 0.22 10.6 7.2 0.22 10.6 5.0 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain RNase_H2-Ydr279 PF09468.5 ETO01961.1 - 0.28 10.3 7.3 0.31 10.2 5.0 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Pox_Ag35 PF03286.9 ETO01961.1 - 0.62 9.5 11.4 0.65 9.4 7.9 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Neur_chan_memb PF02932.11 ETO01961.1 - 1.3 8.8 4.5 1.3 8.8 3.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2072 PF09845.4 ETO01961.1 - 2.1 8.2 10.6 2.8 7.8 7.3 1.2 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Vfa1 PF08432.5 ETO01961.1 - 2.3 8.1 16.8 3.1 7.7 11.7 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Gag_spuma PF03276.9 ETO01961.1 - 3.5 5.8 13.5 3.5 5.8 9.4 1.0 1 0 0 1 1 1 0 Spumavirus gag protein DUF1851 PF08906.6 ETO01963.1 - 0.07 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1851) Pex24p PF06398.6 ETO01963.1 - 0.16 10.7 0.7 0.19 10.4 0.5 1.0 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Eapp_C PF10238.4 ETO01963.1 - 0.25 11.2 4.5 0.31 10.9 3.1 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein SPC25 PF06703.6 ETO01963.1 - 0.44 10.1 2.8 1.6 8.3 1.9 1.9 1 1 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) ROF PF07073.7 ETO01964.1 - 0.082 12.9 0.3 0.13 12.2 0.2 1.5 1 1 0 1 1 1 0 Modulator of Rho-dependent transcription termination (ROF) DUF809 PF05663.6 ETO01964.1 - 0.23 11.3 5.5 0.25 11.2 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF809) Tmemb_161AB PF10268.4 ETO01964.1 - 0.27 9.6 1.1 0.3 9.5 0.8 1.0 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB YqfQ PF14181.1 ETO01964.1 - 0.42 10.6 4.9 0.45 10.5 3.4 1.1 1 0 0 1 1 1 0 YqfQ-like protein Spore_coat_CotO PF14153.1 ETO01964.1 - 3.4 7.0 12.1 4.6 6.6 8.4 1.1 1 0 0 1 1 1 0 Spore coat protein CotO ERAP1_C PF11838.3 ETO01965.1 - 1.1e-15 57.7 0.0 2.4e-07 30.3 0.0 2.0 1 1 1 2 2 2 2 ERAP1-like C-terminal domain NACHT PF05729.7 ETO01966.1 - 2.6e-20 72.7 0.0 4.5e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 ETO01966.1 - 1.1e-06 27.7 5.5 1.8e-06 27.0 3.8 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 ETO01966.1 - 0.00084 19.3 0.0 0.0053 16.7 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 ETO01966.1 - 0.00099 19.2 0.1 0.003 17.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 ETO01966.1 - 0.0014 17.6 0.0 0.011 14.7 0.0 2.3 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 ETO01966.1 - 0.0091 15.7 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain PhoH PF02562.11 ETO01966.1 - 0.018 14.2 0.0 1.3 8.1 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_18 PF13238.1 ETO01966.1 - 0.028 14.7 0.1 0.028 14.7 0.1 2.8 2 1 0 3 3 3 0 AAA domain Torsin PF06309.6 ETO01966.1 - 0.05 13.4 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Torsin RNA_helicase PF00910.17 ETO01966.1 - 0.051 13.7 0.0 0.44 10.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Sigma54_activat PF00158.21 ETO01966.1 - 0.11 11.9 0.0 0.28 10.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.1 ETO01966.1 - 0.12 11.7 0.0 0.29 10.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 ETO01966.1 - 0.13 12.4 0.0 0.64 10.2 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 ETO01966.1 - 2.9 8.7 6.4 0.79 10.5 0.4 3.0 2 1 0 2 2 2 0 AAA domain DEP PF00610.16 ETO01968.1 - 2.7e-15 55.8 0.2 4e-15 55.3 0.2 1.3 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DXPR_C PF13288.1 ETO01968.1 - 0.0021 18.0 0.1 0.0029 17.5 0.1 1.3 1 1 0 1 1 1 1 DXP reductoisomerase C-terminal domain WavE PF07507.6 ETO01968.1 - 0.047 12.5 1.8 0.057 12.2 1.2 1.1 1 0 0 1 1 1 0 WavE lipopolysaccharide synthesis DUF2813 PF11398.3 ETO01968.1 - 0.13 11.3 3.2 0.15 11.1 2.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) PAM2 PF07145.10 ETO01969.1 - 0.013 14.9 1.3 0.013 14.9 0.9 2.9 2 0 0 2 2 2 0 Ataxin-2 C-terminal region DMPK_coil PF08826.5 ETO01969.1 - 0.093 12.6 7.1 0.17 11.7 0.4 2.5 1 1 0 2 2 2 0 DMPK coiled coil domain like Phage_int_SAM_2 PF12834.2 ETO01969.1 - 0.17 12.2 2.3 0.34 11.3 1.4 1.8 1 1 0 1 1 1 0 Phage integrase, N-terminal YlqD PF11068.3 ETO01969.1 - 0.23 11.5 9.6 0.46 10.5 6.7 1.6 1 0 0 1 1 1 0 YlqD protein zf-CpG_bind_C PF12269.3 ETO01969.1 - 0.48 9.8 6.4 0.24 10.8 2.0 1.9 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain DUF3847 PF12958.2 ETO01969.1 - 2.3 8.0 6.6 6.8 6.5 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) Vfa1 PF08432.5 ETO01971.1 - 0.46 10.4 11.9 0.64 10.0 8.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1940 PF09155.5 ETO01972.1 - 0.0082 15.9 0.2 0.02 14.7 0.1 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF1940) Hema_stalk PF08720.5 ETO01972.1 - 0.041 13.4 0.9 0.072 12.5 0.6 1.4 1 1 0 1 1 1 0 Influenza C hemagglutinin stalk Methyltransf_15 PF09445.5 ETO01972.1 - 0.041 13.4 3.1 0.083 12.4 2.0 1.8 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Vps51 PF08700.6 ETO01972.1 - 0.32 10.8 2.7 1.5 8.6 0.2 2.5 2 2 0 2 2 2 0 Vps51/Vps67 HEAT PF02985.17 ETO01973.1 - 2.8e-14 51.8 0.0 0.00022 21.0 0.0 4.2 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.1 ETO01973.1 - 4.3e-11 42.9 0.0 3.8e-05 23.8 0.0 2.2 1 1 1 2 2 2 2 HEAT repeats Cnd1 PF12717.2 ETO01973.1 - 2.1e-07 30.9 0.1 2.2e-06 27.6 0.0 2.1 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 ETO01973.1 - 5.1e-07 29.9 0.0 0.012 16.1 0.0 2.8 1 1 2 3 3 3 2 HEAT-like repeat HEAT_PBS PF03130.11 ETO01973.1 - 3.2e-05 23.9 0.0 0.069 13.6 0.0 3.8 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.2 ETO01973.1 - 0.00014 22.2 0.1 0.74 10.2 0.0 2.7 1 1 1 2 2 2 2 Vacuolar 14 Fab1-binding region TIP120 PF08623.5 ETO01973.1 - 0.00068 19.2 0.7 1.3 8.5 0.1 3.1 1 1 3 4 4 4 3 TATA-binding protein interacting (TIP20) DUF3554 PF12074.3 ETO01973.1 - 0.0012 18.3 0.1 1.2 8.5 0.0 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF3554) CLASP_N PF12348.3 ETO01973.1 - 0.0028 17.0 0.2 0.099 11.9 0.0 2.0 1 1 0 2 2 2 1 CLASP N terminal TAN PF11640.3 ETO01973.1 - 0.0059 16.3 0.2 0.012 15.3 0.1 1.6 1 1 0 1 1 1 1 Telomere-length maintenance and DNA damage repair PAS_10 PF13596.1 ETO01973.1 - 0.0082 16.3 0.1 1.3 9.3 0.0 2.8 1 1 2 3 3 3 1 PAS domain Proteasom_PSMB PF10508.4 ETO01973.1 - 0.013 13.7 0.1 0.021 13.1 0.1 1.3 1 1 0 1 1 1 0 Proteasome non-ATPase 26S subunit Adaptin_N PF01602.15 ETO01973.1 - 0.014 13.7 0.2 0.017 13.5 0.1 1.2 1 0 0 1 1 1 0 Adaptin N terminal region MOR2-PAG1_N PF14222.1 ETO01973.1 - 0.024 13.3 0.1 9.9 4.7 0.0 2.6 1 1 0 2 2 2 0 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 ETO01973.1 - 0.061 13.0 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 Cell morphogenesis C-terminal SusD-like PF12741.2 ETO01973.1 - 0.067 11.7 0.0 0.15 10.6 0.0 1.6 1 1 1 2 2 2 0 Susd and RagB outer membrane lipoprotein CRM1_C PF08767.6 ETO01973.1 - 0.068 12.0 0.2 1 8.1 0.0 2.3 1 1 0 2 2 2 0 CRM1 C terminal TFCD_C PF12612.3 ETO01973.1 - 0.08 12.3 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal NLE PF08154.7 ETO01973.1 - 0.087 12.8 0.2 3.9 7.5 0.0 2.7 2 1 1 3 3 3 0 NLE (NUC135) domain 14-3-3 PF00244.15 ETO01973.1 - 0.12 11.3 1.4 0.22 10.5 0.3 1.7 1 1 1 2 2 2 0 14-3-3 protein Peptidase_S11 PF00768.15 ETO01973.1 - 0.13 11.4 0.0 2.2 7.5 0.0 2.2 1 1 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase PEX11 PF05648.9 ETO01974.1 - 0.016 14.4 2.2 0.11 11.8 0.2 2.0 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) AAA_11 PF13086.1 ETO01974.1 - 0.16 11.5 5.7 0.13 11.7 0.8 2.0 2 0 0 2 2 2 0 AAA domain Peptidase_S49_N PF08496.5 ETO01974.1 - 0.78 9.5 6.9 3.4 7.4 0.5 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Eapp_C PF10238.4 ETO01974.1 - 1 9.2 9.0 0.25 11.2 1.0 2.1 2 0 0 2 2 2 0 E2F-associated phosphoprotein ARF7EP_C PF14949.1 ETO01974.1 - 7.3 7.0 10.6 6.3 7.2 1.6 2.1 2 0 0 2 2 2 0 ARF7 effector protein C-terminus WLM PF08325.5 ETO01975.1 - 0.018 14.9 0.8 0.018 14.8 0.6 1.1 1 0 0 1 1 1 0 WLM domain Integrase_1 PF12835.2 ETO01976.1 - 0.038 13.7 1.0 0.048 13.4 0.7 1.1 1 0 0 1 1 1 0 Integrase Daxx PF03344.10 ETO01977.1 - 2.6 6.4 32.6 3.1 6.1 22.6 1.1 1 0 0 1 1 1 0 Daxx Family QRPTase_C PF01729.14 ETO01977.1 - 3.3 7.2 7.0 0.7 9.3 2.6 1.5 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain WD40 PF00400.27 ETO01978.1 - 3.1e-20 71.2 3.6 7.9e-10 38.2 0.1 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO01978.1 - 0.00025 19.3 0.2 0.028 12.5 0.1 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 HAD PF12710.2 ETO01978.1 - 0.026 14.7 0.1 0.16 12.1 0.0 1.9 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Nucleoporin_N PF08801.6 ETO01978.1 - 0.048 12.4 1.8 0.56 8.8 1.3 2.4 1 1 0 1 1 1 0 Nup133 N terminal like Pox_E2-like PF04497.7 ETO01979.1 - 0.025 12.6 2.8 0.027 12.5 2.0 1.0 1 0 0 1 1 1 0 Poxviridae protein TMEM237 PF15383.1 ETO01979.1 - 0.034 13.2 7.7 0.039 13.0 5.3 1.1 1 0 0 1 1 1 0 Transmembrane protein 237 YPEB PF14620.1 ETO01979.1 - 0.037 13.0 9.7 0.044 12.7 6.7 1.1 1 0 0 1 1 1 0 YpeB sporulation Spc7 PF08317.6 ETO01979.1 - 0.061 11.9 17.3 0.071 11.7 12.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Med8 PF10232.4 ETO01979.1 - 0.082 12.4 8.0 0.089 12.2 5.5 1.1 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 GLTP PF08718.6 ETO01979.1 - 0.1 12.6 5.0 0.13 12.3 3.5 1.3 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) PilJ PF13675.1 ETO01979.1 - 0.17 12.2 1.8 0.21 11.9 1.2 1.2 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF2457 PF10446.4 ETO01979.1 - 0.37 9.4 5.8 0.41 9.3 4.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DOT1 PF08123.8 ETO01979.1 - 0.43 9.8 9.6 0.47 9.7 6.7 1.1 1 0 0 1 1 1 0 Histone methylation protein DOT1 Spc24 PF08286.6 ETO01979.1 - 0.61 9.8 18.8 0.092 12.4 9.5 1.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 PA26 PF04636.8 ETO01979.1 - 0.7 8.5 8.5 0.76 8.4 5.9 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PTPlike_phytase PF14566.1 ETO01979.1 - 0.7 9.9 5.7 0.91 9.5 3.9 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Exonuc_VII_L PF02601.10 ETO01979.1 - 0.72 8.9 12.3 0.86 8.7 8.5 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF87 PF01935.12 ETO01979.1 - 1.1 8.9 8.5 1.4 8.6 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF87 Macoilin PF09726.4 ETO01979.1 - 1.4 7.0 13.8 1.7 6.7 9.6 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF641 PF04859.7 ETO01979.1 - 1.5 8.5 15.8 8.3 6.1 0.5 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) RP-C_C PF11800.3 ETO01979.1 - 1.6 8.3 6.4 1.9 8.1 4.4 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF342 PF03961.8 ETO01979.1 - 1.9 6.7 18.2 2 6.7 12.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Uds1 PF15456.1 ETO01979.1 - 1.9 8.4 10.2 2.6 8.0 7.0 1.1 1 0 0 1 1 1 0 Up-regulated During Septation GCD14 PF08704.5 ETO01979.1 - 2 7.8 7.1 2.1 7.7 4.9 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Peroxin-13_N PF04088.8 ETO01979.1 - 2 8.3 8.1 2.9 7.8 5.6 1.3 1 1 0 1 1 1 0 Peroxin 13, N-terminal region HAUS6_N PF14661.1 ETO01979.1 - 2.2 7.5 12.2 2.7 7.2 8.4 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus APG6 PF04111.7 ETO01979.1 - 2.6 7.0 17.2 2.7 6.9 11.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 GIDA_assoc_3 PF13932.1 ETO01979.1 - 3.2 7.8 8.7 0.45 10.6 2.7 2.0 1 1 1 2 2 2 0 GidA associated domain 3 DUF4337 PF14235.1 ETO01979.1 - 3.6 7.3 15.2 4.3 7.1 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Hom_end_hint PF05203.11 ETO01979.1 - 4.7 6.8 7.6 5.3 6.7 5.3 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint AAA_11 PF13086.1 ETO01979.1 - 7 6.1 10.2 8.7 5.8 7.0 1.2 1 0 0 1 1 1 0 AAA domain Nup88 PF10168.4 ETO01979.1 - 8 4.1 13.2 9.3 3.9 9.1 1.0 1 0 0 1 1 1 0 Nuclear pore component DUF1910 PF08928.5 ETO01979.1 - 8.7 6.4 12.8 1.7 8.6 5.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1910) DUF3573 PF12097.3 ETO01979.1 - 9.2 4.7 12.0 12 4.3 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF4404 PF14357.1 ETO01979.1 - 9.7 6.6 12.6 4.2 7.8 5.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) LRRC37AB_C PF14914.1 ETO01980.1 - 0.63 9.4 8.9 0.08 12.3 2.2 2.2 2 1 1 3 3 3 0 LRRC37A/B like protein 1 C-terminal domain DUF2407_C PF13373.1 ETO01980.1 - 0.82 9.5 3.9 1.5 8.7 2.7 1.5 1 0 0 1 1 1 0 DUF2407 C-terminal domain Cys_rich_VLP PF14194.1 ETO01981.1 - 0.005 16.5 0.5 0.0097 15.6 0.4 1.5 1 0 0 1 1 1 1 Cysteine-rich VLP Fz PF01392.17 ETO01981.1 - 0.11 12.8 3.8 0.16 12.3 2.6 1.1 1 0 0 1 1 1 0 Fz domain Cys_rich_VLP PF14194.1 ETO01982.1 - 0.02 14.6 0.5 0.038 13.7 0.3 1.5 1 0 0 1 1 1 0 Cysteine-rich VLP DUF3707 PF12499.3 ETO01982.1 - 0.086 13.1 4.1 0.35 11.1 3.0 1.8 1 1 1 2 2 2 0 Pherophorin AAA_22 PF13401.1 ETO01983.1 - 0.007 16.5 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Ost4 PF10215.4 ETO01984.1 - 0.0037 16.7 0.2 0.0093 15.4 0.1 1.6 1 0 0 1 1 1 1 Oligosaccaryltransferase DUF1125 PF06563.6 ETO01984.1 - 0.2 11.4 1.4 0.69 9.6 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1125) Tox-MPTase3 PF15639.1 ETO01985.1 - 0.062 13.0 0.4 0.098 12.4 0.3 1.3 1 0 0 1 1 1 0 Metallopeptidase toxin 3 zf-DNA_Pol PF08996.5 ETO01985.1 - 0.065 12.5 0.8 0.095 12.0 0.6 1.2 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger DUF2681 PF10883.3 ETO01985.1 - 0.15 12.3 1.4 0.26 11.5 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) YajC PF02699.10 ETO01985.1 - 3 7.5 7.7 0.29 10.8 1.2 2.2 2 0 0 2 2 2 0 Preprotein translocase subunit DUF1042 PF06294.6 ETO01986.1 - 0.027 14.0 1.0 0.03 13.9 0.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1042) DUF1018 PF06252.7 ETO01986.1 - 0.13 12.7 3.2 0.92 10.0 2.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1018) DUF2183 PF09949.4 ETO01986.1 - 0.25 11.3 2.0 0.65 9.9 1.0 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2183) DapB_C PF05173.9 ETO01986.1 - 0.25 11.0 3.1 0.32 10.7 2.2 1.2 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, C-terminus zf-DHHC PF01529.15 ETO01987.1 - 6.1e-20 71.3 7.1 1.1e-19 70.5 4.9 1.4 1 1 0 1 1 1 1 DHHC palmitoyltransferase NACHT PF05729.7 ETO01989.1 - 1.3e-18 67.1 0.0 4.5e-18 65.4 0.0 1.9 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 ETO01989.1 - 0.00018 21.5 0.2 0.001 19.1 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 ETO01989.1 - 0.0038 16.1 2.2 0.015 14.1 0.1 2.8 2 1 0 2 2 2 1 NB-ARC domain Sigma54_activ_2 PF14532.1 ETO01989.1 - 0.0073 16.3 0.0 0.97 9.4 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.1 ETO01989.1 - 0.014 15.5 1.1 0.14 12.2 0.1 2.8 2 1 0 2 2 2 0 AAA domain SMC_N PF02463.14 ETO01989.1 - 0.033 13.4 0.1 0.12 11.5 0.0 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_5 PF07728.9 ETO01989.1 - 0.044 13.5 0.0 1 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 ETO01989.1 - 0.061 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 ETO01989.1 - 0.11 12.7 1.9 0.29 11.4 0.1 2.7 2 1 0 2 2 2 0 AAA domain ABC_membrane PF00664.18 ETO01991.1 - 6e-33 114.4 3.3 1e-32 113.6 2.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 ETO01991.1 - 3.5e-20 72.6 2.4 6.5e-17 62.1 0.1 3.3 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 ETO01991.1 - 0.0011 18.2 2.5 0.0017 17.6 1.1 1.7 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain DUF4131 PF13567.1 ETO01991.1 - 0.76 9.1 11.5 0.41 10.0 0.9 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Ctf8 PF09696.5 ETO01991.1 - 2.3 8.0 10.5 1.8 8.3 0.3 2.9 2 0 0 2 2 2 0 Ctf8 ABC_tran PF00005.22 ETO01992.1 - 1.8e-20 73.6 0.0 3.3e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 ETO01992.1 - 0.0038 16.7 0.2 0.0088 15.5 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 ETO01992.1 - 0.049 13.9 0.0 0.073 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain UME PF08064.8 ETO01992.1 - 0.057 13.3 1.2 0.097 12.6 0.9 1.3 1 0 0 1 1 1 0 UME (NUC010) domain SMC_N PF02463.14 ETO01992.1 - 0.11 11.7 1.7 0.86 8.7 1.2 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 ETO01992.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 ETO01992.1 - 0.22 11.4 0.6 8.9 6.1 0.0 2.2 1 1 0 2 2 2 0 AAA domain ABC_membrane PF00664.18 ETO01993.1 - 3.4e-34 118.5 6.3 3.9e-34 118.3 4.4 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region CLPTM1 PF05602.7 ETO01993.1 - 0.088 11.5 0.3 0.12 11.1 0.2 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) Herpes_alk_exo PF01771.12 ETO01994.1 - 0.068 11.6 0.0 0.077 11.4 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus alkaline exonuclease DivIC PF04977.10 ETO01995.1 - 0.25 10.8 2.6 0.46 10.0 1.8 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF4169 PF13770.1 ETO01995.1 - 1.7 8.6 7.1 31 4.6 4.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4169) Toxin_64 PF15542.1 ETO01995.1 - 3 8.4 9.0 0.33 11.5 0.5 2.9 3 1 0 3 3 3 0 Putative toxin 64 CTDII PF01556.13 ETO01996.1 - 2.5e-10 40.1 0.0 6.4e-10 38.7 0.0 1.7 2 0 0 2 2 2 1 DnaJ C terminal domain Cob_adeno_trans PF01923.13 ETO01997.1 - 1.5e-43 148.3 0.0 2.2e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 Cobalamin adenosyltransferase Tfb4 PF03850.9 ETO01997.1 - 0.071 12.3 0.1 0.084 12.1 0.0 1.2 1 0 0 1 1 1 0 Transcription factor Tfb4 NRDE PF05742.7 ETO01999.1 - 0.051 12.8 0.3 0.064 12.5 0.2 1.2 1 0 0 1 1 1 0 NRDE protein DUF4325 PF14213.1 ETO02000.1 - 0.48 10.1 4.8 0.4 10.3 1.2 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4325) FH2 PF02181.18 ETO02001.1 - 5.4e-74 249.2 15.7 1e-73 248.3 10.9 1.4 1 0 0 1 1 1 1 Formin Homology 2 Domain LRR_6 PF13516.1 ETO02002.1 - 0.00016 21.3 0.0 0.0027 17.5 0.0 6.2 8 0 0 8 8 8 2 Leucine Rich repeat LRR_4 PF12799.2 ETO02002.1 - 0.00017 21.0 2.4 1 9.0 0.0 4.5 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) CUE PF02845.11 ETO02002.1 - 0.00066 19.1 0.9 0.0013 18.1 0.0 2.0 2 0 0 2 2 2 1 CUE domain LRR_1 PF00560.28 ETO02002.1 - 0.11 12.6 13.7 6.4 7.2 0.0 6.6 5 2 1 6 6 6 0 Leucine Rich Repeat LRR_7 PF13504.1 ETO02002.1 - 1.8 9.1 13.3 34 5.2 0.0 6.9 7 0 0 7 7 7 0 Leucine rich repeat RIB43A PF05914.7 ETO02003.1 - 1.5e-31 109.3 59.9 3.3e-26 91.8 22.5 2.4 2 0 0 2 2 2 2 RIB43A TPR_11 PF13414.1 ETO02004.1 - 2.1e-11 43.2 0.1 2.1e-06 27.2 0.0 2.4 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 ETO02004.1 - 8.8e-07 28.3 0.1 0.0016 18.1 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO02004.1 - 2.2e-06 26.9 0.2 0.0057 16.2 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO02004.1 - 3.2e-05 23.7 0.1 0.005 16.7 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO02004.1 - 0.0075 15.9 0.3 0.89 9.4 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat RCR PF12273.3 ETO02004.1 - 0.013 16.0 0.0 0.5 10.9 0.0 2.3 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red TPR_17 PF13431.1 ETO02004.1 - 0.024 14.8 0.0 0.39 11.0 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETO02004.1 - 0.037 14.6 0.1 1.9 9.3 0.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF883 PF05957.8 ETO02004.1 - 0.12 12.7 2.4 19 5.7 0.2 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF4602 PF15375.1 ETO02005.1 - 0.071 13.1 1.1 0.071 13.1 0.8 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4602) Peptidase_S64 PF08192.6 ETO02007.1 - 0.016 13.5 0.9 0.02 13.2 0.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 HEAT PF02985.17 ETO02009.1 - 1.7e-08 33.8 0.1 0.43 10.8 0.0 5.9 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.1 ETO02009.1 - 2.1e-08 34.3 0.0 0.0012 19.0 0.0 3.1 2 1 1 3 3 3 3 HEAT repeats DNA_pol3_gamma3 PF12169.3 ETO02009.1 - 0.00096 18.9 2.9 0.26 11.0 0.1 3.5 2 2 1 3 3 3 2 DNA polymerase III subunits gamma and tau domain III HEAT_EZ PF13513.1 ETO02009.1 - 0.0011 19.3 0.0 11 6.6 0.0 4.2 3 1 1 4 4 4 1 HEAT-like repeat DUF2732 PF10809.3 ETO02009.1 - 0.0097 15.4 0.6 3.4 7.2 0.0 2.9 1 1 1 2 2 2 2 Protein of unknown function (DUF2732) Y2_Tnp PF04986.8 ETO02009.1 - 0.018 14.8 2.2 0.037 13.7 1.5 1.7 1 1 0 1 1 1 0 Putative transposase Bcr-Abl_Oligo PF09036.5 ETO02009.1 - 0.054 13.4 4.3 3.6 7.6 0.2 3.3 2 1 1 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain Anti-adapt_IraP PF10796.4 ETO02009.1 - 0.11 12.8 4.6 0.84 10.0 0.2 2.7 2 0 0 2 2 2 0 Sigma-S stabilisation anti-adaptor protein DUF645 PF04875.7 ETO02009.1 - 0.16 11.7 1.6 52 3.6 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function, DUF645 Condensin2nSMC PF12422.3 ETO02009.1 - 0.16 11.7 12.4 0.13 12.0 2.4 3.6 1 1 2 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit DNApol3-delta_C PF09115.5 ETO02009.1 - 0.31 11.0 12.2 2 8.4 0.9 3.2 2 2 0 2 2 2 0 DNA polymerase III, delta subunit, C terminal Plasmid_parti PF01672.11 ETO02010.1 - 2.2 8.7 4.8 1.2 9.6 0.1 2.7 3 0 0 3 3 3 0 Putative plasmid partition protein DUF1945 PF09178.5 ETO02011.1 - 0.022 14.6 0.4 0.055 13.3 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1945) ComC PF03047.9 ETO02011.1 - 6.7 6.2 7.6 0.49 9.8 1.4 2.1 2 0 0 2 2 2 0 COMC family Kelch_4 PF13418.1 ETO02012.1 - 1.9e-06 27.5 0.2 0.047 13.4 0.0 2.5 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO02012.1 - 4.4e-06 26.6 0.9 0.0025 17.9 0.2 2.5 1 1 1 2 2 2 2 Kelch motif Kelch_5 PF13854.1 ETO02012.1 - 3.1e-05 23.8 0.9 0.0027 17.6 0.1 2.8 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.20 ETO02012.1 - 0.0025 17.3 1.6 0.031 13.8 0.0 2.5 2 0 0 2 2 2 1 Kelch motif Gly_acyl_tr_N PF06021.6 ETO02013.1 - 0.0092 15.4 1.1 0.016 14.6 0.8 1.4 1 0 0 1 1 1 1 Aralkyl acyl-CoA:amino acid N-acyltransferase PB1 PF00564.19 ETO02013.1 - 0.049 13.2 2.2 0.083 12.5 0.4 2.0 2 0 0 2 2 2 0 PB1 domain Vfa1 PF08432.5 ETO02016.1 - 0.019 14.9 12.2 0.022 14.7 8.5 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF342 PF03961.8 ETO02016.1 - 0.031 12.7 11.1 0.033 12.5 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) UDG PF03167.14 ETO02016.1 - 0.12 11.8 0.2 0.17 11.3 0.1 1.3 1 1 0 1 1 1 0 Uracil DNA glycosylase superfamily TT_ORF1 PF02956.9 ETO02016.1 - 0.12 10.8 3.8 0.14 10.6 2.6 1.0 1 0 0 1 1 1 0 TT viral orf 1 TPR_MLP1_2 PF07926.7 ETO02016.1 - 0.34 10.6 18.2 0.54 10.0 12.4 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Nop25 PF09805.4 ETO02016.1 - 0.34 10.9 15.0 0.47 10.5 10.4 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) APG6 PF04111.7 ETO02016.1 - 0.54 9.2 14.1 0.64 9.0 9.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 RP-C_C PF11800.3 ETO02016.1 - 0.86 9.2 8.0 1.1 8.8 5.5 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Peptidase_S49_N PF08496.5 ETO02016.1 - 0.91 9.3 9.8 1.3 8.7 6.8 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3573 PF12097.3 ETO02016.1 - 1.5 7.3 5.6 1.9 7.0 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Mem_trans PF03547.13 ETO02016.1 - 4.5 5.4 4.9 5.5 5.1 3.4 1.1 1 0 0 1 1 1 0 Membrane transport protein Lge1 PF11488.3 ETO02016.1 - 9.1 6.5 10.1 9.2 6.5 5.2 2.3 1 1 2 3 3 3 0 Transcriptional regulatory protein LGE1 RVT_1 PF00078.22 ETO02018.1 - 1.4e-05 24.5 0.0 2.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_integ_N PF09003.5 ETO02019.1 - 0.029 14.0 0.9 0.1 12.3 0.0 1.9 1 1 1 2 2 2 0 Bacteriophage lambda integrase, N-terminal domain DDE_Tnp_1_7 PF13843.1 ETO02020.1 - 0.026 13.6 0.3 0.036 13.1 0.2 1.3 1 0 0 1 1 1 0 Transposase IS4 DUF45 PF01863.12 ETO02020.1 - 0.026 14.3 0.7 0.031 14.0 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF45 SAM_1 PF00536.25 ETO02020.1 - 0.049 13.8 0.1 0.078 13.1 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) MotCF PF09158.5 ETO02020.1 - 0.21 11.2 2.4 0.2 11.3 0.4 1.7 1 1 1 2 2 2 0 Bacteriophage T4 MotA, C-terminal SopA PF13981.1 ETO02020.1 - 0.22 11.5 3.4 0.1 12.5 0.5 1.7 2 0 0 2 2 2 0 SopA-like central domain DUF1772 PF08592.6 ETO02020.1 - 6.5 6.4 6.3 10 5.8 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) DUF220 PF02713.9 ETO02021.1 - 0.045 13.4 2.6 0.11 12.1 1.8 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF220 WD40 PF00400.27 ETO02022.1 - 8.2e-11 41.3 3.1 2.5e-10 39.8 1.5 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO02022.1 - 0.00021 19.5 0.5 0.00039 18.6 0.4 1.5 1 0 0 1 1 1 1 Nucleoporin Nup120/160 zf-RING_2 PF13639.1 ETO02022.1 - 0.0063 16.3 0.9 0.0063 16.3 0.6 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO02022.1 - 0.013 15.5 0.2 0.013 15.5 0.2 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-BED PF02892.10 ETO02022.1 - 0.25 11.1 3.0 1.4 8.7 0.0 3.3 4 0 0 4 4 4 0 BED zinc finger FliD_N PF02465.13 ETO02022.1 - 1.3 9.4 7.1 0.58 10.5 2.1 2.4 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF4376 PF14301.1 ETO02022.1 - 3.2 7.9 12.5 0.63 10.2 2.8 3.3 1 1 3 4 4 4 0 Domain of unknown function (DUF4376) WD40 PF00400.27 ETO02023.1 - 5.7e-20 70.3 11.8 8.1e-10 38.1 1.8 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO02023.1 - 7.3e-05 21.1 0.2 0.00016 19.9 0.1 1.7 1 1 0 1 1 1 1 Nucleoporin Nup120/160 zf-RanBP PF00641.13 ETO02024.1 - 4.5e-07 28.8 4.7 9e-07 27.8 3.3 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others GatB_Yqey PF02637.13 ETO02025.1 - 0.031 13.9 0.9 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 GatB domain HEAT_2 PF13646.1 ETO02026.1 - 5.3e-26 90.7 0.0 3.1e-08 33.8 0.0 6.1 4 2 5 9 9 9 6 HEAT repeats HEAT PF02985.17 ETO02026.1 - 1.1e-19 68.6 0.5 0.0016 18.3 0.0 8.9 8 0 0 8 8 8 4 HEAT repeat HEAT_EZ PF13513.1 ETO02026.1 - 2.4e-12 46.9 0.0 0.00022 21.6 0.0 6.9 4 2 4 8 8 8 2 HEAT-like repeat DUF3554 PF12074.3 ETO02026.1 - 0.012 15.0 8.3 0.37 10.1 0.3 4.1 3 1 0 4 4 4 0 Domain of unknown function (DUF3554) Complex1_51K PF01512.12 ETO02026.1 - 0.013 15.1 0.1 0.36 10.5 0.0 2.7 2 0 0 2 2 2 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit DUF4428 PF14471.1 ETO02026.1 - 0.015 15.0 4.4 0.19 11.5 0.1 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) HEAT_PBS PF03130.11 ETO02026.1 - 0.025 14.9 0.0 11 6.8 0.0 4.5 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat XkdW PF09636.5 ETO02026.1 - 0.12 12.2 3.7 16 5.4 0.3 4.6 4 1 0 4 4 4 0 XkdW protein NLE PF08154.7 ETO02026.1 - 6.9 6.7 14.9 9.4 6.3 0.0 6.6 9 0 0 9 9 9 0 NLE (NUC135) domain WD40 PF00400.27 ETO02027.1 - 6e-32 108.3 13.6 8.1e-12 44.5 0.1 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO02027.1 - 4.6e-08 31.6 2.6 6.2e-05 21.3 0.4 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 CPSF_A PF03178.10 ETO02027.1 - 0.015 14.4 0.1 0.022 13.8 0.1 1.3 1 0 0 1 1 1 0 CPSF A subunit region Kelch_6 PF13964.1 ETO02030.1 - 5.5e-07 29.4 0.7 0.055 13.6 0.0 4.5 3 1 1 4 4 4 1 Kelch motif Kelch_2 PF07646.10 ETO02030.1 - 6.4e-06 25.7 0.2 0.22 11.3 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO02030.1 - 0.00037 20.2 0.0 0.34 10.7 0.0 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO02030.1 - 0.00039 19.8 0.1 0.14 11.7 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 ETO02030.1 - 0.0036 17.2 0.2 19 5.3 0.0 4.8 5 0 0 5 5 5 1 Kelch motif HSF_DNA-bind PF00447.12 ETO02031.1 - 0.053 13.6 5.0 0.26 11.4 0.8 2.2 2 0 0 2 2 2 0 HSF-type DNA-binding Pneumo_M2 PF07380.6 ETO02031.1 - 0.21 11.6 4.2 1.1 9.3 0.3 2.2 2 0 0 2 2 2 0 Pneumovirus M2 protein DUF2682 PF10909.3 ETO02031.1 - 0.58 10.4 14.0 0.19 12.0 4.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2682) DUF1443 PF07280.6 ETO02032.1 - 0.022 14.3 0.2 0.074 12.6 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1443) CorA PF01544.13 ETO02033.1 - 1e-07 31.3 1.5 1.7e-07 30.5 0.3 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein WD40 PF00400.27 ETO02034.1 - 2.8e-61 201.3 16.3 7.6e-15 54.1 0.3 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO02034.1 - 7.1e-07 27.7 2.9 0.13 10.3 0.1 3.6 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO02034.1 - 8.3e-07 27.6 5.2 4e-05 22.0 0.9 2.7 1 1 2 3 3 3 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO02034.1 - 1.5e-06 27.8 0.5 9e-06 25.3 0.3 2.0 1 1 0 1 1 1 1 PQQ-like domain Nucleoporin_N PF08801.6 ETO02034.1 - 3.3e-05 22.8 9.5 0.075 11.7 5.4 3.3 1 1 0 1 1 1 1 Nup133 N terminal like Gmad1 PF10647.4 ETO02034.1 - 7.5e-05 22.2 2.2 0.017 14.5 0.2 2.2 1 1 1 2 2 2 2 Lipoprotein LpqB beta-propeller domain Coatomer_WDAD PF04053.9 ETO02034.1 - 0.00017 20.5 0.7 0.0003 19.7 0.3 1.5 1 1 0 1 1 1 1 Coatomer WD associated region DUF1258 PF06869.7 ETO02034.1 - 0.00033 19.8 0.4 4.4 6.3 0.0 3.6 1 1 3 4 4 4 1 Protein of unknown function (DUF1258) DUF3732 PF12532.3 ETO02034.1 - 0.0012 18.4 1.0 3.4 7.1 0.0 3.3 1 1 2 3 3 3 1 Protein of unknown function (DUF3732) Glyco_hydro_28 PF00295.12 ETO02034.1 - 0.0022 17.0 4.8 0.4 9.5 0.5 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 28 SGL PF08450.7 ETO02034.1 - 0.0067 15.8 0.0 0.0099 15.2 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Proteasome_A_N PF10584.4 ETO02034.1 - 0.013 14.7 1.1 44 3.5 0.1 4.5 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature DUF3553 PF12073.3 ETO02034.1 - 0.017 14.4 0.1 4.1 6.7 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3553) TFIIIC_delta PF12657.2 ETO02034.1 - 0.025 14.3 2.1 0.21 11.3 1.0 2.6 1 1 1 2 2 2 0 Transcription factor IIIC subunit delta N-term NYD-SP28_assoc PF14775.1 ETO02034.1 - 0.039 13.6 1.2 1.1e+02 2.6 0.0 4.5 5 0 0 5 5 5 0 Sperm tail C-terminal domain Mid2 PF04478.7 ETO02034.1 - 0.078 12.3 1.0 4.8 6.5 0.1 2.6 1 1 2 3 3 3 0 Mid2 like cell wall stress sensor Rpn3_C PF08375.6 ETO02034.1 - 0.12 12.8 0.0 8.6 6.8 0.0 3.2 4 0 0 4 4 4 0 Proteasome regulatory subunit C-terminal DUF4221 PF13970.1 ETO02034.1 - 0.13 11.5 0.3 1.6 7.9 0.1 2.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4221) PD40 PF07676.7 ETO02034.1 - 1 9.1 3.5 11 5.8 0.0 3.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF2201_N PF13203.1 ETO02035.1 - 0.1 11.7 7.7 0.1 11.7 5.4 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Sporozoite_P67 PF05642.6 ETO02035.1 - 1.1 7.0 10.8 1.2 6.8 7.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.9 ETO02035.1 - 1.5 6.7 12.7 1.5 6.7 8.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Pox_RNA_Pol_19 PF05320.7 ETO02035.1 - 1.8 8.3 9.1 2.3 7.9 6.3 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit YqfQ PF14181.1 ETO02035.1 - 2 8.4 7.8 2.4 8.1 5.4 1.3 1 0 0 1 1 1 0 YqfQ-like protein Sec62 PF03839.11 ETO02035.1 - 2.2 7.6 12.3 2.5 7.4 8.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 ARD PF03079.9 ETO02035.1 - 2.8 7.8 6.7 3.3 7.6 4.6 1.2 1 0 0 1 1 1 0 ARD/ARD' family eIF-3c_N PF05470.7 ETO02035.1 - 4.3 5.2 13.0 4.9 5.1 9.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus ECIST_Cterm PF14784.1 ETO02036.1 - 0.2 11.6 2.6 0.27 11.2 1.8 1.4 1 1 0 1 1 1 0 C-terminal domain of the ECSIT protein ARD PF03079.9 ETO02036.1 - 0.92 9.4 5.7 1.1 9.2 4.0 1.1 1 0 0 1 1 1 0 ARD/ARD' family CDC45 PF02724.9 ETO02036.1 - 1.8 6.5 8.6 1.8 6.4 6.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Sec62 PF03839.11 ETO02036.1 - 3.4 6.9 8.5 3.7 6.9 5.9 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 RVT_1 PF00078.22 ETO02037.1 - 3.8e-13 49.2 0.5 6.8e-13 48.4 0.4 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.27 ETO02039.1 - 5.5e-21 73.6 3.1 4.8e-07 29.4 0.1 4.2 4 1 0 4 4 4 3 WD domain, G-beta repeat DUF3657 PF12394.3 ETO02040.1 - 0.25 11.4 6.2 1.8 8.7 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3657) BK_channel_a PF03493.13 ETO02040.1 - 0.53 10.2 4.9 2.1 8.3 1.7 2.3 1 1 1 2 2 2 0 Calcium-activated BK potassium channel alpha subunit WD40 PF00400.27 ETO02042.1 - 4.5e-18 64.3 0.5 5.7e-10 38.6 0.0 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO02042.1 - 1.5e-07 29.9 0.0 0.0037 15.4 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF1975 PF09318.5 ETO02042.1 - 0.019 14.5 0.6 0.025 14.1 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1975) WD40 PF00400.27 ETO02043.1 - 1.6e-12 46.8 0.0 5.7e-12 45.0 0.1 1.7 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF3637 PF12337.3 ETO02043.1 - 0.013 15.4 0.5 0.027 14.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3637) Nup160 PF11715.3 ETO02043.1 - 0.057 11.5 0.0 0.063 11.4 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO02043.1 - 0.073 11.8 0.0 0.079 11.6 0.0 1.1 1 0 0 1 1 1 0 Nup133 N terminal like Glyco_hydro_47 PF01532.15 ETO02044.1 - 5.5e-17 61.5 0.7 6.5e-17 61.3 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 XkdW PF09636.5 ETO02045.1 - 0.0018 18.1 0.0 0.0026 17.6 0.0 1.2 1 0 0 1 1 1 1 XkdW protein TIP120 PF08623.5 ETO02045.1 - 0.0044 16.6 0.0 0.0071 15.9 0.0 1.3 1 0 0 1 1 1 1 TATA-binding protein interacting (TIP20) DUF458 PF04308.7 ETO02045.1 - 0.0057 16.3 0.1 0.0094 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF458) HEAT_2 PF13646.1 ETO02045.1 - 0.063 13.5 0.1 0.11 12.7 0.0 1.5 1 1 0 1 1 1 0 HEAT repeats N_Asn_amidohyd PF14736.1 ETO02045.1 - 0.091 11.6 0.2 0.27 10.0 0.0 1.7 2 0 0 2 2 2 0 Protein N-terminal asparagine amidohydrolase TAS2R PF05296.8 ETO02048.1 - 0.011 14.6 0.9 0.045 12.6 0.4 1.8 2 0 0 2 2 2 0 Mammalian taste receptor protein (TAS2R) DUF2207 PF09972.4 ETO02048.1 - 0.015 13.9 0.1 0.019 13.5 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Peroxin-13_N PF04088.8 ETO02048.1 - 0.029 14.3 0.1 0.037 13.9 0.1 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region RNA_pol_Rpb1_1 PF04997.7 ETO02048.1 - 0.069 12.3 4.1 0.091 12.0 2.8 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 TMCO5 PF14992.1 ETO02048.1 - 0.095 11.8 1.5 0.1 11.6 1.0 1.3 1 1 0 1 1 1 0 TMCO5 family Zip PF02535.17 ETO02048.1 - 0.25 10.2 1.8 0.33 9.9 0.5 1.5 1 1 1 2 2 2 0 ZIP Zinc transporter PBP1_TM PF14812.1 ETO02048.1 - 9.3 6.6 9.2 0.53 10.6 0.6 2.5 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ResIII PF04851.10 ETO02050.1 - 1.6e-06 28.1 0.0 2.3e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 ETO02050.1 - 0.00028 20.4 0.0 0.0004 19.9 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.1 ETO02050.1 - 0.002 17.8 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain DEAD_2 PF06733.10 ETO02050.1 - 0.003 16.9 5.9 0.023 14.1 0.1 2.7 3 0 0 3 3 3 2 DEAD_2 AAA_11 PF13086.1 ETO02050.1 - 0.0071 15.9 0.0 0.0096 15.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF853 PF05872.7 ETO02050.1 - 0.0072 14.7 0.0 0.01 14.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) SNF2_N PF00176.18 ETO02050.1 - 0.1 11.3 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain zf-TRAF PF02176.13 ETO02051.1 - 0.00025 21.3 0.7 0.00025 21.3 0.5 2.6 2 1 0 2 2 2 1 TRAF-type zinc finger SHOCT PF09851.4 ETO02053.1 - 1.7 8.2 5.2 3 7.4 0.2 2.7 2 0 0 2 2 2 0 Short C-terminal domain Apq12 PF12716.2 ETO02054.1 - 0.19 11.4 0.2 0.19 11.4 0.2 2.2 2 1 0 2 2 2 0 Nuclear pore assembly and biogenesis NIF PF03031.13 ETO02055.1 - 1.5e-21 76.7 0.0 2.7e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hydantoinase_A PF01968.13 ETO02055.1 - 0.083 11.9 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase PXA PF02194.10 ETO02055.1 - 0.2 11.2 3.5 0.29 10.6 2.4 1.3 1 0 0 1 1 1 0 PXA domain RbsD_FucU PF05025.8 ETO02055.1 - 0.36 11.1 0.0 0.36 11.1 0.0 2.4 2 1 0 2 2 2 0 RbsD / FucU transport protein family Ndc1_Nup PF09531.5 ETO02055.1 - 0.68 8.2 8.2 0.65 8.3 5.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AIF_C PF14721.1 ETO02055.1 - 0.68 10.1 5.7 1.1 9.5 4.0 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Spore_coat_CotO PF14153.1 ETO02055.1 - 1.5 8.2 18.6 1.9 7.8 12.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Neur_chan_memb PF02932.11 ETO02055.1 - 3 7.6 6.3 3.1 7.6 4.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Band_3_cyto PF07565.8 ETO02055.1 - 5.8 6.3 9.5 6.3 6.2 6.6 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SurA_N PF09312.6 ETO02056.1 - 0.073 12.9 2.6 0.087 12.6 1.8 1.2 1 0 0 1 1 1 0 SurA N-terminal domain DUF1694 PF07997.6 ETO02056.1 - 0.69 9.8 6.0 0.99 9.3 4.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1694) YL1 PF05764.8 ETO02056.1 - 4.5 6.8 19.8 5.1 6.6 13.7 1.0 1 0 0 1 1 1 0 YL1 nuclear protein IMD PF08397.6 ETO02056.1 - 8.3 5.6 18.1 9.9 5.3 12.5 1.1 1 0 0 1 1 1 0 IRSp53/MIM homology domain U-box PF04564.10 ETO02057.1 - 7.3e-13 48.2 0.0 2.7e-12 46.4 0.0 2.1 1 0 0 1 1 1 1 U-box domain DUF755 PF05501.6 ETO02058.1 - 3.4 7.7 9.7 2.4 8.2 5.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF755) SR-25 PF10500.4 ETO02058.1 - 4.9 6.5 11.6 8.2 5.8 8.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Mucin PF01456.12 ETO02059.1 - 0.18 11.6 60.8 0.017 14.8 2.9 3.6 3 0 0 3 3 3 0 Mucin-like glycoprotein Saw1 PF11561.3 ETO02060.1 - 0.0011 18.3 2.9 0.0016 17.8 2.0 1.3 1 0 0 1 1 1 1 Single strand annealing-weakened 1 tRNA_anti-codon PF01336.20 ETO02060.1 - 0.0056 16.5 0.4 1.5 8.7 0.0 3.2 3 1 0 3 3 3 1 OB-fold nucleic acid binding domain Radial_spoke PF04712.7 ETO02060.1 - 0.027 13.2 2.5 0.036 12.8 1.7 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein DUF223 PF02721.9 ETO02060.1 - 0.069 13.2 0.0 0.13 12.3 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function DUF223 AF1Q PF15017.1 ETO02060.1 - 0.43 10.5 7.8 3.5 7.5 1.8 2.2 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator CENP-B_dimeris PF09026.5 ETO02060.1 - 1.1 9.4 5.4 0.85 9.8 2.0 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 ETO02060.1 - 5.8 6.4 9.5 0.14 11.6 1.7 1.8 2 0 0 2 2 2 0 Nucleoplasmin DUF3899 PF13038.1 ETO02060.1 - 6.1 7.0 6.0 33 4.7 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) WASH-7_N PF14745.1 ETO02061.1 - 0.0034 15.6 2.8 0.0039 15.4 2.0 1.0 1 0 0 1 1 1 1 WASH complex subunit 7, N-terminal Pkinase PF00069.20 ETO02063.1 - 0.00031 19.9 1.9 0.00045 19.4 1.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Methyltrn_RNA_4 PF09936.4 ETO02063.1 - 0.021 14.3 0.0 0.025 14.0 0.0 1.1 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase U-box PF04564.10 ETO02064.1 - 7e-09 35.5 0.0 2e-08 34.0 0.0 1.9 1 0 0 1 1 1 1 U-box domain Kelch_6 PF13964.1 ETO02064.1 - 0.00022 21.2 0.4 0.22 11.7 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 ETO02064.1 - 0.17 11.4 1.1 2.7 7.6 0.1 2.6 2 0 0 2 2 2 0 Kelch motif BLOC1_2 PF10046.4 ETO02067.1 - 0.03 14.4 1.7 0.05 13.7 0.1 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UIM PF02809.15 ETO02067.1 - 0.063 12.8 0.0 0.063 12.8 0.0 3.0 3 0 0 3 3 3 0 Ubiquitin interaction motif Phe_hydrox_dim PF07976.7 ETO02068.1 - 0.032 13.8 1.4 1.3 8.6 1.0 2.1 1 1 0 1 1 1 0 Phenol hydroxylase, C-terminal dimerisation domain Inhibitor_I53 PF11714.3 ETO02068.1 - 0.31 11.0 5.1 0.7 9.9 3.6 1.5 1 0 0 1 1 1 0 Thrombin inhibitor Madanin N6_N4_Mtase PF01555.13 ETO02068.1 - 0.39 10.1 6.9 0.57 9.6 4.8 1.3 1 0 0 1 1 1 0 DNA methylase Exonuc_VII_L PF02601.10 ETO02068.1 - 1.8 7.6 9.6 2.4 7.2 6.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit HAUS6_N PF14661.1 ETO02068.1 - 4.6 6.5 10.2 6.1 6.1 7.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus PAPA-1 PF04795.7 ETO02068.1 - 6.6 7.5 9.5 4.8 7.9 0.6 2.3 2 0 0 2 2 2 0 PAPA-1-like conserved region PBP1_TM PF14812.1 ETO02068.1 - 9.7 6.5 15.9 26 5.2 7.8 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WD40 PF00400.27 ETO02069.1 - 5.5e-10 38.7 0.0 0.00012 21.7 0.0 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF912 PF06024.7 ETO02070.1 - 0.59 10.2 5.1 0.57 10.2 2.4 1.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) NBP1 PF08537.5 ETO02070.1 - 1 8.4 10.8 1.1 8.3 7.5 1.0 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 Ribonuclease PF00545.15 ETO02070.1 - 3.3 7.8 5.4 20 5.3 3.7 2.0 1 1 0 1 1 1 0 ribonuclease DUF4014 PF13198.1 ETO02072.1 - 0.26 11.7 2.9 0.53 10.7 0.1 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF4014) Med19 PF10278.4 ETO02073.1 - 0.56 9.8 20.3 0.56 9.8 14.1 1.0 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Eapp_C PF10238.4 ETO02073.1 - 4 7.3 6.5 4.2 7.2 4.5 1.0 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF2947 PF11163.3 ETO02074.1 - 0.0076 15.8 2.6 0.78 9.3 0.2 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2947) Ldl_recept_a PF00057.13 ETO02075.1 - 3.6e-11 42.7 32.3 1e-06 28.4 8.0 3.0 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A DUF2605 PF10792.4 ETO02076.1 - 0.032 13.9 1.4 0.33 10.6 0.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2605) GDPD PF03009.12 ETO02076.1 - 0.079 12.4 0.2 0.14 11.5 0.2 1.4 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family AAA PF00004.24 ETO02077.1 - 6.8e-07 29.5 0.0 1e-06 28.9 0.0 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETO02077.1 - 1.3e-06 28.1 0.0 8e-06 25.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 ETO02077.1 - 2.6e-05 24.0 0.2 5.7e-05 23.0 0.0 1.6 1 1 1 2 2 2 1 AAA domain ABC_tran PF00005.22 ETO02077.1 - 0.00068 19.9 0.0 0.00081 19.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_18 PF13238.1 ETO02077.1 - 0.0013 19.0 0.1 0.0017 18.6 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO02077.1 - 0.0014 19.4 0.0 0.0041 17.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 ETO02077.1 - 0.0027 17.6 0.1 0.012 15.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 ETO02077.1 - 0.0054 16.8 0.1 0.015 15.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 ETO02077.1 - 0.058 13.0 0.4 0.58 9.7 0.1 2.1 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 ETO02077.1 - 0.06 13.5 0.1 0.13 12.4 0.1 1.9 1 1 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 ETO02077.1 - 0.15 11.7 0.4 0.61 9.7 0.0 2.0 2 1 1 3 3 3 0 NTPase DUF883 PF05957.8 ETO02081.1 - 0.0066 16.8 3.9 0.0066 16.8 2.7 4.2 1 1 3 4 4 4 1 Bacterial protein of unknown function (DUF883) DUF4407 PF14362.1 ETO02081.1 - 0.24 10.3 45.1 0.47 9.3 23.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Myosin_tail_1 PF01576.14 ETO02081.1 - 0.37 8.4 75.4 1 6.9 52.3 1.6 1 1 0 1 1 1 0 Myosin tail Reo_sigmaC PF04582.7 ETO02081.1 - 2.3 7.3 15.5 1.9 7.5 5.4 2.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ADIP PF11559.3 ETO02081.1 - 2.7 7.8 85.6 0.71 9.7 19.2 4.9 1 1 4 5 5 5 0 Afadin- and alpha -actinin-Binding DUF3584 PF12128.3 ETO02081.1 - 3 5.0 69.0 4 4.6 47.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF972 PF06156.8 ETO02081.1 - 4.4 7.6 71.7 0.39 11.0 9.2 4.3 1 1 3 4 4 4 0 Protein of unknown function (DUF972) NTPase_1 PF03266.10 ETO02082.1 - 0.087 12.5 0.0 0.087 12.5 0.0 1.1 1 0 0 1 1 1 0 NTPase HEAT_2 PF13646.1 ETO02083.1 - 0.015 15.5 0.0 2.4 8.5 0.0 2.1 2 0 0 2 2 2 0 HEAT repeats CLASP_N PF12348.3 ETO02083.1 - 0.025 13.9 2.7 0.13 11.5 1.8 2.0 1 1 0 1 1 1 0 CLASP N terminal Imm16 PF15565.1 ETO02083.1 - 0.061 13.1 0.6 0.15 11.9 0.1 1.9 1 1 0 2 2 2 0 Immunity protein 16 Latrotoxin_C PF15658.1 ETO02083.1 - 0.089 12.6 2.7 0.61 9.9 0.3 2.5 1 1 1 2 2 2 0 Latrotoxin C-terminal domain DUF1546 PF07571.8 ETO02083.1 - 0.093 12.8 0.2 6.1 7.0 0.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1546) DNApol3-delta_C PF09115.5 ETO02083.1 - 1.1 9.2 7.4 0.32 11.0 3.2 1.5 2 0 0 2 2 2 0 DNA polymerase III, delta subunit, C terminal C_GCAxxG_C_C PF09719.5 ETO02083.1 - 1.4 8.7 6.0 5.5 6.8 1.0 2.4 1 1 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) GCK PF07802.6 ETO02083.1 - 6 7.0 10.1 0.86 9.7 0.6 2.6 2 1 1 3 3 3 0 GCK domain HEAT_2 PF13646.1 ETO02085.1 - 5.6e-18 65.0 0.0 7.8e-08 32.4 0.0 5.2 4 1 1 5 5 5 4 HEAT repeats HEAT PF02985.17 ETO02085.1 - 3.6e-17 60.8 0.2 0.00065 19.5 0.0 6.9 8 0 0 8 8 7 3 HEAT repeat HEAT_EZ PF13513.1 ETO02085.1 - 1.4e-10 41.2 0.0 6.6e-06 26.4 0.0 5.9 4 3 3 7 7 7 2 HEAT-like repeat DUF2435 PF10363.4 ETO02085.1 - 1.8e-05 24.5 6.0 0.83 9.5 0.0 4.9 4 1 1 5 5 5 2 Protein of unknown function (DUF2435) Cnd1 PF12717.2 ETO02085.1 - 0.00011 22.0 21.7 0.23 11.2 0.0 5.6 3 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 ENTH PF01417.15 ETO02085.1 - 0.00025 20.9 10.5 0.02 14.7 2.0 4.7 3 1 1 4 4 4 1 ENTH domain DUF1444 PF07285.6 ETO02085.1 - 0.0058 15.9 7.6 0.027 13.7 0.5 3.5 4 0 0 4 4 4 1 Protein of unknown function (DUF1444) HEAT_PBS PF03130.11 ETO02085.1 - 0.0087 16.4 0.0 0.58 10.7 0.0 3.3 2 0 0 2 2 2 1 PBS lyase HEAT-like repeat DUF3554 PF12074.3 ETO02085.1 - 0.016 14.6 7.6 0.053 12.9 2.2 3.5 2 2 1 3 3 3 0 Domain of unknown function (DUF3554) Octopine_DH PF02317.12 ETO02085.1 - 0.048 13.3 0.9 0.36 10.4 0.1 2.9 3 1 1 4 4 4 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Lumazine_bd_2 PF12893.2 ETO02085.1 - 0.066 13.7 0.0 1.3 9.5 0.0 3.1 3 0 0 3 3 3 0 Putative lumazine-binding Vac14_Fab1_bd PF12755.2 ETO02085.1 - 0.13 12.6 7.5 2.8 8.4 0.0 4.8 4 2 1 5 5 5 0 Vacuolar 14 Fab1-binding region Syntaphilin PF15290.1 ETO02085.1 - 0.32 10.4 7.2 0.16 11.4 0.1 3.0 3 0 0 3 3 3 0 Golgi-localised syntaxin-1-binding clamp DNA_alkylation PF08713.6 ETO02085.1 - 0.61 9.5 8.0 3.6 7.0 0.0 3.5 3 2 1 4 4 4 0 DNA alkylation repair enzyme IPK PF03770.11 ETO02085.1 - 2 8.0 14.5 0.13 11.8 2.7 3.4 2 1 0 4 4 4 0 Inositol polyphosphate kinase DUF3944 PF13099.1 ETO02085.1 - 3.9 7.0 15.9 2.2 7.8 0.1 7.0 9 0 0 9 9 9 0 Domain of unknown function (DUF3944) Aconitase PF00330.15 ETO02086.1 - 0.54 8.6 2.6 0.5 8.7 1.8 1.0 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) HrpJ PF07201.6 ETO02086.1 - 8.3 6.3 9.5 10 6.0 6.6 1.0 1 0 0 1 1 1 0 HrpJ-like domain DUF1241 PF06840.6 ETO02088.1 - 0.052 12.7 0.3 0.091 12.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) SIMPL PF04402.9 ETO02088.1 - 0.065 13.0 0.0 0.076 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF541) FliD_C PF07195.7 ETO02088.1 - 0.071 12.4 2.0 0.092 12.0 0.9 1.3 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus NPV_P10 PF05531.7 ETO02088.1 - 0.075 13.2 3.4 0.12 12.6 1.8 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Acyl-ACP_TE PF01643.12 ETO02088.1 - 0.1 11.4 0.3 0.19 10.6 0.2 1.4 1 1 0 1 1 1 0 Acyl-ACP thioesterase BLOC1_2 PF10046.4 ETO02088.1 - 0.13 12.4 3.7 0.27 11.3 2.6 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YlbD_coat PF14071.1 ETO02088.1 - 0.17 11.9 4.5 0.12 12.4 1.9 1.7 1 1 0 1 1 1 0 Putative coat protein PRESAN PF09687.5 ETO02088.1 - 0.47 10.5 7.4 0.15 12.1 2.4 2.1 1 1 1 2 2 2 0 Plasmodium RESA N-terminal Lzipper-MIP1 PF14389.1 ETO02088.1 - 0.77 9.8 4.8 2.2 8.4 2.7 2.1 1 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 CENP-Q PF13094.1 ETO02088.1 - 8.7 6.3 9.5 1.5 8.8 1.2 2.6 1 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2072 PF09845.4 ETO02089.1 - 0.085 12.7 0.6 0.12 12.2 0.2 1.4 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) NYD-SP28 PF14772.1 ETO02090.1 - 0.068 13.2 1.0 0.068 13.2 0.7 3.1 2 1 1 3 3 3 0 Sperm tail Syntaxin_2 PF14523.1 ETO02090.1 - 0.071 13.1 12.7 0.22 11.5 0.3 2.3 2 0 0 2 2 2 0 Syntaxin-like protein Lectin_N PF03954.9 ETO02090.1 - 0.59 9.5 7.4 0.27 10.6 3.3 1.8 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF948 PF06103.6 ETO02090.1 - 0.62 9.9 8.8 5.6 6.8 0.2 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.5 ETO02090.1 - 0.76 9.8 15.4 0.36 10.9 7.7 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Spc7 PF08317.6 ETO02090.1 - 0.82 8.2 16.6 0.13 10.9 6.8 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein HOOK PF05622.7 ETO02090.1 - 1.1 7.0 23.3 0.39 8.4 1.1 2.0 2 0 0 2 2 2 0 HOOK protein TPR_MLP1_2 PF07926.7 ETO02090.1 - 1.4 8.6 23.9 5.8 6.6 16.5 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Kinetocho_Slk19 PF12709.2 ETO02090.1 - 3 7.9 17.1 1.9 8.6 5.7 2.6 2 1 0 2 2 2 0 Central kinetochore-associated DUF4200 PF13863.1 ETO02090.1 - 5.9 6.8 21.3 0.27 11.2 1.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF489 PF04356.7 ETO02090.1 - 6.2 6.3 9.7 0.65 9.5 3.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF489) OmpH PF03938.9 ETO02090.1 - 8.7 6.2 18.3 3.7 7.4 6.4 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) PP2C_C PF07830.8 ETO02090.1 - 8.8 6.5 6.3 3.2 7.9 0.2 2.7 2 1 1 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain AbiH PF14253.1 ETO02090.1 - 9.4 5.7 8.9 60 3.1 6.2 1.9 1 1 0 1 1 1 0 Bacteriophage abortive infection AbiH FliD_C PF07195.7 ETO02090.1 - 9.5 5.4 10.2 0.18 11.0 1.3 2.1 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus MDFI PF15316.1 ETO02091.1 - 0.23 11.4 8.0 0.29 11.1 5.5 1.1 1 0 0 1 1 1 0 MyoD family inhibitor DUF572 PF04502.8 ETO02091.1 - 0.31 10.1 16.2 0.34 10.1 11.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) RR_TM4-6 PF06459.7 ETO02091.1 - 2.6 7.8 9.4 3 7.6 6.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.2 ETO02091.1 - 4 4.9 12.1 4.8 4.7 8.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GET2 PF08690.5 ETO02091.1 - 5.6 6.1 8.0 7.4 5.7 5.6 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 NIF3 PF01784.13 ETO02093.1 - 0.13 11.8 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) Flu_M1 PF00598.14 ETO02094.1 - 0.077 12.3 1.2 0.1 11.9 0.9 1.2 1 0 0 1 1 1 0 Influenza Matrix protein (M1) DUF4512 PF14975.1 ETO02094.1 - 2.9 8.7 7.8 1.4 9.8 3.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) WD40 PF00400.27 ETO02095.1 - 6.3e-74 241.4 16.2 2.7e-11 42.9 0.1 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO02095.1 - 2.2e-09 36.0 4.5 0.032 12.3 0.0 5.0 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO02095.1 - 4.8e-08 31.7 0.1 3.8e-05 22.1 0.0 2.6 1 1 1 2 2 2 2 Cytochrome D1 heme domain Kelch_2 PF07646.10 ETO02095.1 - 2.6e-05 23.8 2.2 0.032 13.9 0.1 4.5 4 0 0 4 4 4 1 Kelch motif PQQ_2 PF13360.1 ETO02095.1 - 0.00021 20.8 0.0 0.019 14.4 0.0 2.5 1 1 0 1 1 1 1 PQQ-like domain Kelch_4 PF13418.1 ETO02095.1 - 0.0055 16.4 2.0 6.9 6.5 0.0 4.0 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO02095.1 - 0.012 15.7 18.3 1.2 9.4 0.0 6.1 7 1 1 8 8 8 0 Kelch motif Kelch_1 PF01344.20 ETO02095.1 - 0.049 13.1 6.2 4.6 6.8 0.1 3.8 4 0 0 4 4 4 0 Kelch motif Kelch_3 PF13415.1 ETO02095.1 - 0.052 13.7 0.6 1.6 9.0 0.0 2.9 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO02096.1 - 6.5e-09 35.1 2.2 0.0001 21.7 0.1 2.6 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETO02096.1 - 2.8e-06 26.9 0.3 0.0026 17.4 0.0 2.9 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO02096.1 - 2.1e-05 24.0 0.1 0.15 11.9 0.1 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.1 ETO02096.1 - 5.3e-05 23.0 0.4 0.45 10.5 0.0 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO02096.1 - 0.00072 19.6 0.2 1.1 9.5 0.1 3.0 3 0 0 3 3 3 2 Kelch motif Glycos_transf_N PF04413.11 ETO02096.1 - 0.038 13.1 0.0 0.17 11.0 0.0 1.8 2 0 0 2 2 2 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) HTH_Tnp_Tc3_2 PF01498.13 ETO02097.1 - 4.4e-06 26.6 2.5 5.7e-06 26.3 0.2 2.3 2 1 1 3 3 3 1 Transposase HTH_28 PF13518.1 ETO02097.1 - 0.0022 17.9 0.1 0.0064 16.4 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain DDE_3 PF13358.1 ETO02097.1 - 0.0037 17.0 0.2 0.005 16.6 0.2 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.1 ETO02097.1 - 0.0065 16.0 0.2 0.016 14.8 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain PAX PF00292.13 ETO02097.1 - 0.011 15.5 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 'Paired box' domain HTH_7 PF02796.10 ETO02097.1 - 0.062 13.1 0.2 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase LZ_Tnp_IS481 PF13011.1 ETO02097.1 - 0.063 13.6 0.1 0.1 12.9 0.1 1.3 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 P22_Cro PF14549.1 ETO02097.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro BrkDBD PF09607.5 ETO02097.1 - 0.16 11.5 0.1 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 Brinker DNA-binding domain DUF3626 PF12294.3 ETO02099.1 - 0.0026 16.8 1.0 0.003 16.6 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3626) DUF1283 PF06932.6 ETO02099.1 - 0.91 9.5 4.1 0.25 11.3 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1283) RNA_GG_bind PF10258.4 ETO02099.1 - 5 6.8 9.7 1.6 8.4 0.5 2.7 3 0 0 3 3 3 0 PHAX RNA-binding domain Gin PF10764.4 ETO02100.1 - 0.03 14.0 0.4 0.062 13.0 0.2 1.5 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin Ribosomal_L22e PF01776.12 ETO02103.1 - 0.00057 19.8 2.2 0.0008 19.3 0.7 1.8 2 1 0 2 2 2 1 Ribosomal L22e protein family MinC_N PF05209.8 ETO02103.1 - 0.084 12.6 0.1 3 7.6 0.0 2.1 2 0 0 2 2 2 0 Septum formation inhibitor MinC, N-terminal domain DUF3837 PF12939.2 ETO02104.1 - 0.0024 17.8 0.3 0.0089 16.0 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3837) R-HINP1I PF11463.3 ETO02104.1 - 0.015 14.6 0.1 0.02 14.2 0.1 1.2 1 0 0 1 1 1 0 R.HinP1I restriction endonuclease NLBH PF05211.7 ETO02104.1 - 0.032 13.4 0.2 0.043 13.0 0.1 1.1 1 0 0 1 1 1 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) WD40 PF00400.27 ETO02105.1 - 4.5e-17 61.2 4.5 0.00015 21.4 0.2 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO02105.1 - 0.017 13.3 0.0 0.023 12.8 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 WD40 PF00400.27 ETO02107.1 - 3.9e-11 42.3 15.4 0.0025 17.6 1.4 5.1 4 0 0 4 4 4 4 WD domain, G-beta repeat DUF4394 PF14339.1 ETO02110.1 - 0.16 11.1 0.8 0.28 10.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4394) MMS19_C PF12460.3 ETO02111.1 - 4.6e-08 32.2 4.0 4.6e-08 32.2 2.8 1.8 2 1 0 2 2 2 1 RNAPII transcription regulator C-terminal Sod_Ni PF09055.6 ETO02111.1 - 0.03 14.6 0.3 0.11 12.9 0.2 1.8 1 0 0 1 1 1 0 Nickel-containing superoxide dismutase MMS19_N PF14500.1 ETO02112.1 - 3e-26 92.2 2.5 5.4e-26 91.4 1.8 1.4 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II DUF1036 PF06282.6 ETO02113.1 - 0.29 11.4 3.2 0.62 10.4 1.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1036) PGA2 PF07543.7 ETO02114.1 - 0.0065 16.2 1.8 0.012 15.4 0.1 1.9 2 0 0 2 2 2 1 Protein trafficking PGA2 DUF3090 PF11290.3 ETO02114.1 - 0.093 12.1 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) WD40 PF00400.27 ETO02115.1 - 3.4e-53 175.7 26.0 1.4e-10 40.6 2.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO02115.1 - 2e-12 46.0 6.8 0.0016 16.6 1.6 5.0 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Cyto_heme_lyase PF01265.12 ETO02116.1 - 2.5e-36 125.5 12.4 3e-33 115.5 8.6 2.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase REC114-like PF15165.1 ETO02116.1 - 0.05 13.3 0.4 0.098 12.3 0.2 1.4 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like HMD PF03201.11 ETO02116.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase WD40 PF00400.27 ETO02117.1 - 4.8e-85 276.7 17.9 7.6e-14 50.9 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO02117.1 - 5.4e-09 34.7 6.1 0.026 12.6 0.1 5.2 1 1 3 5 5 5 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO02117.1 - 2e-05 24.2 0.5 0.00076 19.0 0.1 2.8 1 1 1 2 2 2 1 PQQ-like domain Nucleoporin_N PF08801.6 ETO02117.1 - 5.5e-05 22.0 13.7 0.58 8.8 0.5 5.8 1 1 5 6 6 6 3 Nup133 N terminal like BBS2_Mid PF14783.1 ETO02117.1 - 6.4e-05 22.7 4.3 1.3 8.8 0.1 4.9 2 2 1 3 3 3 3 Ciliary BBSome complex subunit 2, middle region Cytochrom_D1 PF02239.11 ETO02117.1 - 0.0031 15.8 0.1 1.7 6.8 0.0 2.6 1 1 2 3 3 3 2 Cytochrome D1 heme domain PD40 PF07676.7 ETO02117.1 - 0.026 14.1 5.4 6.4 6.5 0.0 5.3 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Ricin_B_lectin PF00652.17 ETO02117.1 - 0.029 14.3 5.8 0.26 11.3 0.1 3.4 1 1 3 4 4 4 0 Ricin-type beta-trefoil lectin domain Resistin PF06954.6 ETO02117.1 - 0.067 13.4 7.9 28 5.0 0.0 5.6 3 2 2 6 6 6 0 Resistin WD40 PF00400.27 ETO02118.1 - 4.6e-72 235.5 14.6 3.9e-12 45.5 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO02118.1 - 8.5e-06 24.1 3.6 0.48 8.5 0.0 4.7 1 1 4 5 5 5 3 Nucleoporin Nup120/160 DPPIV_N PF00930.16 ETO02118.1 - 9.1e-06 24.4 0.8 0.11 11.0 0.0 3.7 1 1 4 5 5 5 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.7 ETO02118.1 - 4.3e-05 23.0 3.2 11 5.7 0.0 5.5 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO02118.1 - 0.00058 19.3 0.7 0.0046 16.4 0.5 2.4 1 1 0 1 1 1 1 PQQ-like domain DUF1513 PF07433.6 ETO02118.1 - 0.0042 16.0 0.1 0.57 9.0 0.0 3.4 1 1 1 3 3 3 1 Protein of unknown function (DUF1513) Resistin PF06954.6 ETO02118.1 - 0.0079 16.4 1.5 67 3.8 0.0 5.1 2 1 4 6 6 6 0 Resistin Phage_CI_repr PF07022.8 ETO02118.1 - 0.026 14.5 0.1 8.7 6.5 0.0 3.3 3 0 0 3 3 3 0 Bacteriophage CI repressor helix-turn-helix domain Nucleoporin_N PF08801.6 ETO02118.1 - 0.043 12.5 6.1 0.41 9.3 0.1 3.5 1 1 0 3 3 3 0 Nup133 N terminal like DUF2415 PF10313.4 ETO02118.1 - 0.15 11.7 0.5 27 4.5 0.0 3.8 4 0 0 4 4 4 0 Uncharacterised protein domain (DUF2415) TFIIA_gamma_N PF02268.11 ETO02119.1 - 0.028 14.0 0.5 0.052 13.1 0.0 1.7 2 0 0 2 2 2 0 Transcription initiation factor IIA, gamma subunit, helical domain Pox_A_type_inc PF04508.7 ETO02119.1 - 0.028 14.1 0.0 0.068 12.9 0.0 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat ET PF01684.11 ETO02120.1 - 0.26 11.3 3.2 0.47 10.5 0.2 2.5 2 0 0 2 2 2 0 ET module IFT46_B_C PF12317.3 ETO02121.1 - 0.048 13.0 2.3 0.078 12.3 1.6 1.2 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal Lig_chan PF00060.21 ETO02121.1 - 0.57 9.8 2.3 20 4.8 0.1 2.7 3 0 0 3 3 3 0 Ligand-gated ion channel NACHT PF05729.7 ETO02122.1 - 4.2e-18 65.5 0.0 8.3e-18 64.5 0.0 1.5 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 ETO02122.1 - 0.00099 18.0 2.0 0.0027 16.6 1.3 1.8 1 1 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 ETO02122.1 - 0.0024 18.0 0.3 0.014 15.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain Sec23_helical PF04815.10 ETO02122.1 - 0.0039 16.6 1.0 2.1 7.8 0.0 2.7 2 0 0 2 2 2 2 Sec23/Sec24 helical domain AAA_16 PF13191.1 ETO02122.1 - 0.033 14.1 0.1 0.18 11.8 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.21 ETO02122.1 - 0.12 11.8 0.0 0.56 9.6 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF4433 PF14487.1 ETO02123.1 - 0.035 13.8 0.3 6.2 6.4 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4433) DUF1708 PF08101.6 ETO02123.1 - 0.04 12.7 2.2 0.097 11.4 1.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1708) NACHT PF05729.7 ETO02123.1 - 0.081 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain rve_2 PF13333.1 ETO02123.1 - 0.89 9.6 3.5 0.83 9.7 0.3 2.5 3 1 0 3 3 3 0 Integrase core domain Filament PF00038.16 ETO02124.1 - 0.0021 17.5 19.6 0.013 15.0 9.7 2.0 2 0 0 2 2 2 1 Intermediate filament protein TMF_DNA_bd PF12329.3 ETO02124.1 - 0.0027 17.4 32.5 0.024 14.4 6.8 3.2 2 1 1 3 3 3 2 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 ETO02124.1 - 0.017 14.2 20.3 0.023 13.7 14.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 ETO02124.1 - 0.023 14.7 22.9 0.06 13.3 11.2 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Reo_sigmaC PF04582.7 ETO02124.1 - 0.029 13.5 1.2 0.73 8.9 0.2 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 ETO02124.1 - 0.032 11.9 19.8 0.039 11.6 13.7 1.1 1 0 0 1 1 1 0 Myosin tail SRP1_TIP1 PF00660.12 ETO02124.1 - 0.04 13.7 0.6 0.81 9.5 0.1 2.3 2 0 0 2 2 2 0 Seripauperin and TIP1 family GAS PF13851.1 ETO02124.1 - 0.053 12.7 27.8 0.19 10.8 14.2 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 ETO02124.1 - 0.078 12.7 26.7 1.1 9.0 0.3 2.7 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Mod_r PF07200.8 ETO02124.1 - 0.12 12.3 24.6 0.12 12.3 8.3 2.5 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Phage_GP20 PF06810.6 ETO02124.1 - 0.17 11.3 29.5 2.1 7.8 0.7 2.6 2 1 0 2 2 2 0 Phage minor structural protein GP20 CCDC-167 PF15188.1 ETO02124.1 - 0.21 11.5 21.9 0.21 11.5 0.3 3.3 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 DUF1699 PF08004.6 ETO02124.1 - 0.21 11.1 6.2 0.13 11.7 1.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1699) Fungal_trans_2 PF11951.3 ETO02124.1 - 0.22 10.1 1.6 0.26 9.8 1.1 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF4515 PF14988.1 ETO02124.1 - 0.23 11.0 30.0 1.5 8.4 12.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4515) BLOC1_2 PF10046.4 ETO02124.1 - 0.26 11.4 26.3 0.59 10.3 6.8 2.9 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2968 PF11180.3 ETO02124.1 - 0.43 9.9 20.7 0.12 11.6 9.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) ISG65-75 PF11727.3 ETO02124.1 - 0.68 8.9 14.9 0.11 11.5 7.5 1.6 2 0 0 2 2 2 0 Invariant surface glycoprotein DUF4200 PF13863.1 ETO02124.1 - 0.71 9.8 30.4 3.8 7.4 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) CorA PF01544.13 ETO02124.1 - 0.73 8.8 6.7 1.1 8.2 4.6 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF3365 PF11845.3 ETO02124.1 - 0.92 9.3 5.7 0.85 9.4 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3365) 7TMR-HDED PF07697.6 ETO02124.1 - 1.1 9.0 16.2 75 2.9 11.3 2.2 1 1 0 1 1 1 0 7TM-HD extracellular DUF4509 PF14970.1 ETO02124.1 - 1.2 8.8 14.0 4.5 6.8 6.6 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4509) Jnk-SapK_ap_N PF09744.4 ETO02124.1 - 1.2 9.0 20.6 9.7 6.1 0.1 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF4404 PF14357.1 ETO02124.1 - 1.3 9.4 15.9 0.57 10.6 7.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) CHASE3 PF05227.8 ETO02124.1 - 1.3 8.6 12.6 2.2 7.9 5.8 2.8 1 1 2 3 3 3 0 CHASE3 domain Tox-GHH2 PF15635.1 ETO02124.1 - 2 8.8 7.9 0.53 10.6 3.0 1.9 2 1 0 2 2 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin 2 Kinesin-relat_1 PF12711.2 ETO02124.1 - 2.1 8.8 18.9 0.33 11.3 9.2 2.3 2 1 0 2 2 2 0 Kinesin motor FlgN PF05130.7 ETO02124.1 - 2.2 8.5 16.7 0.37 11.0 8.8 1.7 2 0 0 2 2 2 0 FlgN protein DUF848 PF05852.6 ETO02124.1 - 3.1 7.6 17.2 2.6 7.9 8.4 2.1 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) V_ATPase_I PF01496.14 ETO02124.1 - 3.2 5.4 13.3 4.2 5.1 9.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LXG PF04740.7 ETO02124.1 - 3.4 7.3 19.5 2.4 7.9 0.3 3.5 2 1 2 4 4 4 0 LXG domain of WXG superfamily DUF2203 PF09969.4 ETO02124.1 - 4.4 7.5 11.8 1.4e+02 2.7 8.2 2.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) bZIP_1 PF00170.16 ETO02124.1 - 4.9 7.1 24.3 0.29 11.1 2.5 3.8 1 1 3 4 4 4 0 bZIP transcription factor Tropomyosin_1 PF12718.2 ETO02124.1 - 5.3 6.8 24.8 0.93 9.3 5.3 2.2 1 1 1 2 2 2 0 Tropomyosin like HAUS-augmin3 PF14932.1 ETO02124.1 - 5.5 6.0 22.8 0.39 9.8 11.0 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DUF641 PF04859.7 ETO02124.1 - 6 6.6 17.1 5.7 6.7 6.6 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) CENP-F_leu_zip PF10473.4 ETO02124.1 - 6.3 6.6 25.3 4.5 7.1 13.2 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.3 ETO02124.1 - 6.3 6.6 23.6 7 6.5 12.1 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Med9 PF07544.8 ETO02124.1 - 6.3 6.6 25.8 5.2 6.8 4.6 3.6 2 1 2 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 DivIC PF04977.10 ETO02124.1 - 6.4 6.3 32.6 0.56 9.7 7.7 4.0 1 1 3 4 4 4 0 Septum formation initiator IncA PF04156.9 ETO02124.1 - 6.6 6.2 26.8 6.5 6.3 13.6 2.3 1 1 0 2 2 2 0 IncA protein Laminin_II PF06009.7 ETO02124.1 - 7 6.4 16.2 11 5.7 0.2 2.4 2 1 0 2 2 2 0 Laminin Domain II YjcZ PF13990.1 ETO02124.1 - 7.6 5.5 8.3 1.4 8.0 3.3 1.5 2 0 0 2 2 2 0 YjcZ-like protein Shugoshin_N PF07558.6 ETO02124.1 - 7.7 6.3 20.5 0.26 11.0 0.5 3.8 3 1 1 4 4 3 0 Shugoshin N-terminal coiled-coil region YlqD PF11068.3 ETO02124.1 - 7.9 6.5 26.0 4.3 7.3 11.7 2.7 1 1 1 2 2 2 0 YlqD protein AAA_13 PF13166.1 ETO02124.1 - 8.4 4.7 26.9 1.8 6.9 12.1 1.9 1 1 1 2 2 2 0 AAA domain DUF4446 PF14584.1 ETO02124.1 - 9.2 6.0 16.4 20 5.0 6.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) Kelch_1 PF01344.20 ETO02125.1 - 0.0018 17.8 2.8 0.33 10.5 0.0 2.9 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO02125.1 - 0.014 15.5 2.5 6.3 7.1 0.0 3.1 2 1 2 4 4 4 0 Kelch motif TFIIE-A_C-term PF11521.3 ETO02128.1 - 0.1 12.5 1.9 0.15 11.9 0.4 1.8 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha DUF4340 PF14238.1 ETO02130.1 - 0.098 12.3 0.6 0.17 11.5 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4340) GTP_EFTU_D2 PF03144.20 ETO02131.1 - 1.2e-09 38.1 0.1 2.1e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 ETO02131.1 - 1.9e-09 37.0 0.0 2.6e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D3 PF03143.12 ETO02131.1 - 0.025 14.7 0.0 0.068 13.3 0.0 1.7 2 0 0 2 2 2 0 Elongation factor Tu C-terminal domain FAR1 PF03101.10 ETO02133.1 - 0.2 12.2 3.5 0.14 12.7 0.9 1.8 2 0 0 2 2 2 0 FAR1 DNA-binding domain FcoT PF10862.3 ETO02134.1 - 0.017 14.6 1.2 0.017 14.6 0.8 1.5 1 1 0 1 1 1 0 FcoT-like thioesterase domain CPSase_L_D3 PF02787.14 ETO02134.1 - 0.034 13.9 3.9 0.048 13.4 2.5 1.4 1 1 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Thymidylate_kin PF02223.12 ETO02135.1 - 1.4e-33 115.8 1.9 6e-31 107.2 1.3 2.3 1 1 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.1 ETO02135.1 - 0.0021 18.3 0.9 0.0067 16.7 0.6 2.1 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 ETO02135.1 - 0.0021 17.3 1.0 0.0087 15.3 0.1 2.4 1 1 1 2 2 2 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 ETO02135.1 - 0.0023 18.7 0.6 0.0064 17.2 0.4 1.9 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 ETO02135.1 - 0.006 16.4 1.8 0.097 12.5 0.1 2.4 2 1 0 2 2 2 1 AAA domain ADK PF00406.17 ETO02135.1 - 0.011 15.6 0.1 0.22 11.3 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase AAA_22 PF13401.1 ETO02135.1 - 0.017 15.2 0.1 0.037 14.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 ETO02135.1 - 0.061 13.1 0.1 0.23 11.3 0.0 2.0 1 1 1 2 2 2 0 AAA domain MiaE PF06175.6 ETO02135.1 - 0.066 12.5 0.2 0.066 12.5 0.1 1.5 2 0 0 2 2 2 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) AAA_28 PF13521.1 ETO02135.1 - 0.072 13.0 0.3 0.13 12.2 0.2 1.5 1 1 0 1 1 1 0 AAA domain DMAP_binding PF06464.6 ETO02135.1 - 0.13 12.8 1.0 0.24 11.9 0.7 1.6 1 0 0 1 1 1 0 DMAP1-binding Domain DUF4441 PF14536.1 ETO02135.1 - 0.87 9.5 5.6 3.3 7.7 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4441) Ras PF00071.17 ETO02136.1 - 9.3e-42 142.1 0.2 1.4e-41 141.5 0.1 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO02136.1 - 7e-14 52.3 0.2 4.6e-13 49.7 0.0 2.1 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO02136.1 - 8.8e-09 34.8 0.4 1.4e-08 34.1 0.3 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO02136.1 - 1.2e-05 24.8 0.1 2e-05 24.0 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 ETO02136.1 - 0.02 14.0 0.1 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TFIID_90kDa PF04494.10 ETO02136.1 - 0.3 11.1 2.2 2 8.4 1.5 2.0 1 1 0 1 1 1 0 WD40 associated region in TFIID subunit FAD_binding_6 PF00970.19 ETO02137.1 - 2.4e-18 66.1 0.0 6.8e-18 64.6 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 ETO02137.1 - 4.9e-07 30.2 0.0 0.0004 20.9 0.0 2.6 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_9 PF08021.6 ETO02137.1 - 0.067 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain RabGAP-TBC PF00566.13 ETO02138.1 - 1.9e-25 89.5 16.4 8e-25 87.5 4.4 3.4 2 1 1 3 3 3 3 Rab-GTPase-TBC domain WD40 PF00400.27 ETO02139.1 - 7.9e-56 184.0 14.3 3.2e-12 45.8 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO02139.1 - 1.5e-16 59.7 5.3 0.0016 16.7 0.1 5.2 2 2 2 5 5 5 5 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO02139.1 - 9.2e-05 22.3 0.6 3.9 7.4 0.0 4.7 4 1 1 5 5 5 2 Domain of unknown function (DUF3601) HAD PF12710.2 ETO02139.1 - 0.091 12.9 0.8 1.5 8.9 0.0 2.6 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Abhydrolase_5 PF12695.2 ETO02140.1 - 2.6e-18 66.1 0.1 1e-17 64.2 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETO02140.1 - 2.1e-08 34.3 0.0 7.4e-05 22.7 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETO02140.1 - 9.7e-08 31.4 0.0 5.2e-07 29.0 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 ETO02140.1 - 6.6e-07 28.9 0.1 1.6e-05 24.4 0.0 2.4 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase LIP PF03583.9 ETO02140.1 - 0.00032 20.0 0.0 0.00071 18.8 0.0 1.5 2 0 0 2 2 2 1 Secretory lipase Abhydrolase_3 PF07859.8 ETO02140.1 - 0.0011 18.6 0.0 0.0017 17.9 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 ETO02140.1 - 0.0012 18.3 0.0 0.0047 16.3 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DUF1749 PF08538.5 ETO02140.1 - 0.004 16.0 0.0 0.0052 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_1 PF00561.15 ETO02140.1 - 0.0094 15.5 0.0 1.9 7.9 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.13 ETO02140.1 - 0.03 13.6 0.0 0.061 12.5 0.0 1.6 1 1 0 1 1 1 0 Dienelactone hydrolase family BAAT_C PF08840.6 ETO02140.1 - 0.035 13.8 0.0 0.31 10.7 0.0 1.9 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal NAD_binding_2 PF03446.10 ETO02142.1 - 1.4e-24 86.7 1.4 5.3e-13 49.1 0.0 2.4 2 0 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 ETO02142.1 - 2.9e-22 78.9 0.6 4.9e-14 52.4 0.0 3.3 3 0 0 3 3 3 3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 ETO02142.1 - 0.0052 16.8 0.0 0.0052 16.8 0.0 2.1 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase LYTB PF02401.13 ETO02142.1 - 0.01 14.7 0.2 0.017 14.0 0.1 1.3 1 0 0 1 1 1 0 LytB protein Aminotran_3 PF00202.16 ETO02143.1 - 2.8e-99 332.1 0.5 5e-97 324.7 0.4 2.0 1 1 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 ETO02143.1 - 0.0026 16.7 0.0 0.0041 16.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 ETO02143.1 - 0.076 12.1 0.0 1 8.4 0.0 2.1 1 1 0 1 1 1 0 Beta-eliminating lyase YmaF PF12788.2 ETO02143.1 - 0.1 12.7 0.1 0.23 11.6 0.1 1.6 1 0 0 1 1 1 0 YmaF family Pkinase PF00069.20 ETO02144.1 - 1e-08 34.6 0.0 1.3e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO02144.1 - 0.083 11.9 0.1 0.12 11.4 0.0 1.4 1 1 0 1 1 1 0 Protein tyrosine kinase RGS PF00615.14 ETO02146.1 - 2.4e-08 34.1 6.5 3e-08 33.7 2.0 3.0 2 0 0 2 2 2 1 Regulator of G protein signaling domain Pkinase PF00069.20 ETO02146.1 - 1.6e-05 24.2 0.1 5.1e-05 22.5 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain DUF2360 PF10152.4 ETO02146.1 - 0.03 14.6 1.2 2.4 8.4 0.1 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Succ_DH_flav_C PF02910.15 ETO02146.1 - 0.043 13.6 1.3 0.082 12.7 0.0 2.1 2 0 0 2 2 2 0 Fumarate reductase flavoprotein C-term Methyltransf_12 PF08242.7 ETO02146.1 - 1.3 9.5 5.8 0.6 10.6 0.5 3.1 3 1 1 4 4 4 0 Methyltransferase domain Pkinase PF00069.20 ETO02147.1 - 9.9e-18 64.2 0.5 7.8e-17 61.2 0.0 2.4 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO02147.1 - 0.0075 15.3 0.0 0.023 13.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase RGM_N PF06535.7 ETO02148.1 - 0.13 12.2 1.2 5.6 6.9 0.0 2.7 1 1 1 3 3 3 0 Repulsive guidance molecule (RGM) N-terminus NACHT PF05729.7 ETO02151.1 - 1.7e-07 31.0 0.0 2e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 NACHT domain DUF2075 PF09848.4 ETO02151.1 - 0.0046 15.9 0.1 0.0093 14.9 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 ETO02151.1 - 0.006 16.5 0.0 0.0062 16.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 ETO02151.1 - 0.009 16.1 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 ETO02151.1 - 0.0093 14.8 0.2 0.015 14.2 0.1 1.6 1 1 0 1 1 1 1 NB-ARC domain SMC_N PF02463.14 ETO02151.1 - 0.012 14.8 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_19 PF13245.1 ETO02151.1 - 0.015 15.0 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Part of AAA domain DAP3 PF10236.4 ETO02151.1 - 0.016 14.1 0.0 0.03 13.2 0.0 1.4 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Torsin PF06309.6 ETO02151.1 - 0.061 13.2 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 Torsin AAA_18 PF13238.1 ETO02151.1 - 0.063 13.5 0.0 0.098 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 ETO02152.1 - 0.00018 21.6 0.1 0.00073 19.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETO02152.1 - 0.00053 20.3 5.4 0.0021 18.3 0.0 3.2 2 1 2 4 4 4 1 AAA domain NACHT PF05729.7 ETO02152.1 - 0.00066 19.3 0.0 0.0021 17.7 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 ETO02152.1 - 0.0081 16.9 1.3 0.11 13.3 0.0 2.9 2 1 1 3 3 3 1 AAA domain UPF0079 PF02367.12 ETO02152.1 - 0.0089 15.6 0.1 0.043 13.4 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 ETO02152.1 - 0.014 14.8 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 ETO02152.1 - 0.02 14.0 0.0 0.041 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ATP_bind_2 PF03668.10 ETO02152.1 - 0.022 13.8 0.0 0.53 9.3 0.0 2.2 2 0 0 2 2 2 0 P-loop ATPase protein family AAA_14 PF13173.1 ETO02152.1 - 0.026 14.4 2.2 3.6 7.5 0.4 2.8 2 0 0 2 2 2 0 AAA domain HnRNP_M PF11532.3 ETO02152.1 - 0.029 14.4 0.7 0.08 13.0 0.5 1.8 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein M AAA_33 PF13671.1 ETO02152.1 - 0.032 14.0 0.0 0.068 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 ETO02152.1 - 0.034 14.3 2.7 0.19 11.9 0.0 2.7 1 1 1 2 2 2 0 RNA helicase PAP_central PF04928.12 ETO02152.1 - 0.059 12.1 0.2 0.13 11.0 0.2 1.6 1 0 0 1 1 1 0 Poly(A) polymerase central domain Sigma54_activat PF00158.21 ETO02152.1 - 0.06 12.8 0.1 0.28 10.6 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.22 ETO02152.1 - 0.067 13.4 0.3 0.31 11.3 0.0 2.2 2 1 0 2 2 2 0 ABC transporter AAA_30 PF13604.1 ETO02152.1 - 0.093 12.2 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Laminin_II PF06009.7 ETO02153.1 - 0.0085 15.8 6.3 0.0085 15.8 4.4 2.4 1 1 1 2 2 2 1 Laminin Domain II PMC2NT PF08066.7 ETO02153.1 - 0.13 12.5 5.0 0.3 11.4 0.8 3.1 2 1 2 4 4 4 0 PMC2NT (NUC016) domain Nup54 PF13874.1 ETO02153.1 - 0.47 10.1 13.0 0.51 9.9 3.5 2.4 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 Seryl_tRNA_N PF02403.17 ETO02153.1 - 1.3 9.1 29.5 4.3 7.3 8.2 2.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Hormone_1 PF00103.15 ETO02153.1 - 1.5 8.1 12.0 0.18 11.1 0.7 2.5 1 1 1 2 2 2 0 Somatotropin hormone family DDE_Tnp_IS66 PF03050.9 ETO02153.1 - 2.8 7.0 7.6 4.4 6.4 5.1 1.5 1 1 0 1 1 1 0 Transposase IS66 family COG2 PF06148.6 ETO02153.1 - 3.1 7.6 17.4 1.3 8.8 0.4 3.4 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Uds1 PF15456.1 ETO02153.1 - 4.8 7.1 16.2 86 3.1 11.3 2.5 1 1 0 1 1 1 0 Up-regulated During Septation Prominin PF05478.6 ETO02153.1 - 6 4.2 16.6 2.7 5.4 5.3 2.1 1 1 1 2 2 2 0 Prominin DUF948 PF06103.6 ETO02153.1 - 7.9 6.4 14.7 0.86 9.5 1.3 3.8 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4297 PF14130.1 ETO02155.1 - 0.043 13.7 2.3 0.047 13.6 1.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4297) Las1 PF04031.8 ETO02156.1 - 0.033 13.8 0.0 0.044 13.4 0.0 1.2 1 0 0 1 1 1 0 Las1-like ROK PF00480.15 ETO02156.1 - 0.083 12.7 0.1 0.11 12.2 0.0 1.3 1 1 0 1 1 1 0 ROK family CAP_GLY PF01302.20 ETO02157.1 - 8.1e-05 22.2 0.2 0.00015 21.3 0.1 1.5 2 0 0 2 2 2 1 CAP-Gly domain RNase_H PF00075.19 ETO02158.1 - 1.4e-21 77.2 0.0 2e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 ETO02158.1 - 0.00031 20.4 0.5 0.00089 18.9 0.4 1.8 1 1 0 1 1 1 1 Reverse transcriptase-like Peptidase_C14 PF00656.17 ETO02159.1 - 0.001 18.8 0.1 0.0018 18.0 0.1 1.4 1 1 0 1 1 1 1 Caspase domain SAM_2 PF07647.12 ETO02160.1 - 0.016 15.0 0.2 14 5.5 0.0 3.7 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO02160.1 - 0.08 13.1 1.0 28 4.9 0.0 3.6 4 0 0 4 4 4 0 SAM domain (Sterile alpha motif) KilA-N PF04383.8 ETO02160.1 - 0.22 11.1 4.4 4.4 6.9 0.0 2.9 3 1 0 3 3 3 0 KilA-N domain Cauli_AT PF03233.8 ETO02160.1 - 2 8.1 10.0 0.44 10.2 3.4 2.5 1 1 0 2 2 2 0 Aphid transmission protein CCDC92 PF14916.1 ETO02161.1 - 0.42 10.2 6.0 6 6.5 0.1 2.7 3 0 0 3 3 3 0 Coiled-coil domain of unknown function Peptidase_M1 PF01433.15 ETO02162.1 - 0.011 14.9 0.0 0.013 14.6 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M1 DUF3784 PF12650.2 ETO02163.1 - 0.029 14.3 1.3 0.041 13.8 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) Peptidase_M36 PF02128.10 ETO02164.1 - 0.024 13.4 0.2 0.027 13.3 0.1 1.1 1 0 0 1 1 1 0 Fungalysin metallopeptidase (M36) Kelch_2 PF07646.10 ETO02165.1 - 0.023 14.4 0.1 2.1 8.2 0.0 3.4 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.1 ETO02165.1 - 0.027 14.2 0.3 3.2 7.6 0.0 3.2 3 0 0 3 3 3 0 Galactose oxidase, central domain ATP-synt_E_2 PF08112.6 ETO02166.1 - 0.037 14.0 4.3 0.18 11.9 0.2 3.2 2 0 0 2 2 2 0 ATP synthase epsilon subunit Linker_histone PF00538.14 ETO02166.1 - 0.19 11.8 4.6 15 5.8 0.1 4.0 3 2 2 5 5 5 0 linker histone H1 and H5 family Picorna_P3A PF06363.6 ETO02166.1 - 0.39 10.7 6.7 8.9 6.3 1.1 3.7 3 1 0 3 3 3 0 Picornaviridae P3A protein STAT_int PF02865.12 ETO02166.1 - 3.5 7.6 7.7 2 8.3 1.4 2.9 1 1 2 3 3 3 0 STAT protein, protein interaction domain HEAT PF02985.17 ETO02168.1 - 7.8e-14 50.4 0.0 0.036 14.1 0.0 6.7 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.1 ETO02168.1 - 4.8e-12 45.9 0.0 3e-05 24.2 0.0 3.9 3 1 1 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 ETO02168.1 - 2e-07 31.2 0.0 3.2 8.3 0.0 4.9 5 0 0 5 5 5 3 HEAT-like repeat DUF3554 PF12074.3 ETO02168.1 - 0.0051 16.2 0.6 0.047 13.1 0.0 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF3554) WD40 PF00400.27 ETO02169.1 - 1.8e-20 72.0 11.9 6e-10 38.6 1.2 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO02169.1 - 8.6e-07 27.4 1.4 0.0021 16.3 0.2 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF956 PF06115.6 ETO02173.1 - 0.022 14.3 0.5 0.057 13.0 0.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF956) HHH_4 PF14490.1 ETO02173.1 - 0.044 13.5 0.0 0.088 12.5 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix containing domain GreA_GreB_N PF03449.10 ETO02173.1 - 0.074 13.1 0.0 0.074 13.1 0.0 1.8 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal Mhr1 PF12829.2 ETO02173.1 - 2.2 8.1 8.5 20 5.0 0.1 3.8 4 1 0 4 4 4 0 Transcriptional regulation of mitochondrial recombination DUF4004 PF13171.1 ETO02174.1 - 0.024 14.7 2.3 0.035 14.2 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4004) CENP-F_leu_zip PF10473.4 ETO02175.1 - 0.0013 18.5 48.0 0.043 13.6 7.4 3.1 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 ETO02175.1 - 0.0039 16.7 14.2 0.0039 16.7 9.8 3.1 1 1 3 4 4 4 3 Intermediate filament protein Reo_sigmaC PF04582.7 ETO02175.1 - 0.0086 15.2 7.7 0.017 14.3 1.3 2.0 1 1 1 2 2 2 1 Reovirus sigma C capsid protein Mod_r PF07200.8 ETO02175.1 - 0.043 13.7 50.2 0.13 12.2 10.0 3.5 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein ERM PF00769.14 ETO02175.1 - 0.049 13.1 48.9 0.5 9.8 34.0 2.1 1 1 0 1 1 1 0 Ezrin/radixin/moesin family GAS PF13851.1 ETO02175.1 - 0.12 11.4 62.1 0.18 10.9 16.2 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF869 PF05911.6 ETO02175.1 - 0.17 10.0 48.0 0.004 15.4 21.9 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) APG6 PF04111.7 ETO02175.1 - 0.21 10.5 55.7 0.13 11.2 10.9 2.7 1 1 1 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 ETO02175.1 - 0.26 10.8 47.0 0.14 11.7 13.3 2.9 1 1 2 3 3 3 0 IncA protein ADIP PF11559.3 ETO02175.1 - 0.38 10.6 58.9 13 5.6 9.8 3.6 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 ETO02175.1 - 0.43 10.3 58.1 0.73 9.5 10.4 2.8 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.2 ETO02175.1 - 0.6 9.9 56.0 0.17 11.7 23.1 3.0 1 1 2 3 3 3 0 Tropomyosin like CALCOCO1 PF07888.6 ETO02175.1 - 0.7 8.1 39.9 2.1 6.5 27.7 1.7 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3574 PF12098.3 ETO02175.1 - 0.85 9.2 5.3 0.42 10.2 1.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3574) bZIP_1 PF00170.16 ETO02175.1 - 0.88 9.5 52.9 0.17 11.8 0.8 6.2 2 1 3 6 6 6 0 bZIP transcription factor HAP1_N PF04849.8 ETO02175.1 - 0.91 8.4 43.5 0.42 9.5 27.5 2.2 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Atg14 PF10186.4 ETO02175.1 - 1.1 8.1 48.1 0.0095 14.9 13.3 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 CCDC155 PF14662.1 ETO02175.1 - 5.5 6.5 44.5 8.9 5.8 8.5 2.7 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 DUF3584 PF12128.3 ETO02175.1 - 7.6 3.7 44.7 13 2.9 30.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) PH_2 PF08458.5 ETO02176.1 - 1.3 8.9 4.9 1.5 8.7 3.4 1.1 1 0 0 1 1 1 0 Plant pleckstrin homology-like region MRG PF05712.8 ETO02176.1 - 1.9 7.3 4.6 1.9 7.3 3.2 1.0 1 0 0 1 1 1 0 MRG Mononeg_mRNAcap PF14318.1 ETO02177.1 - 0.0015 17.6 0.2 0.0023 17.0 0.2 1.3 1 0 0 1 1 1 1 Mononegavirales mRNA-capping region V AAA-ATPase_like PF09820.4 ETO02177.1 - 0.043 12.9 2.8 0.054 12.6 1.9 1.1 1 0 0 1 1 1 0 Predicted AAA-ATPase DNA_pol_phi PF04931.8 ETO02178.1 - 0.2 9.3 27.0 0.63 7.7 18.7 1.6 1 1 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.9 ETO02178.1 - 0.47 8.4 14.8 0.53 8.2 10.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Raftlin PF15250.1 ETO02178.1 - 1.4 7.3 8.6 1.7 7.0 6.0 1.0 1 0 0 1 1 1 0 Raftlin SDA1 PF05285.7 ETO02178.1 - 3.2 6.9 20.3 3.3 6.8 14.1 1.1 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 ETO02178.1 - 3.6 5.9 19.3 3.8 5.8 13.4 1.0 1 0 0 1 1 1 0 Daxx Family DDHD PF02862.12 ETO02178.1 - 5.1 6.8 6.3 6 6.5 4.4 1.1 1 0 0 1 1 1 0 DDHD domain Nop14 PF04147.7 ETO02178.1 - 7 4.4 20.8 7.4 4.3 14.4 1.0 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.12 ETO02178.1 - 9.5 4.9 6.4 11 4.7 4.4 1.0 1 0 0 1 1 1 0 Presenilin WD40 PF00400.27 ETO02179.1 - 0.0066 16.2 0.0 0.018 14.8 0.0 1.7 1 0 0 1 1 1 1 WD domain, G-beta repeat zf-TRAF PF02176.13 ETO02180.1 - 1.3e-05 25.4 3.9 1.3e-05 25.4 2.7 2.5 3 0 0 3 3 3 1 TRAF-type zinc finger Glyco_hydro_12 PF01670.11 ETO02180.1 - 0.14 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 12 zf-RING_2 PF13639.1 ETO02180.1 - 0.22 11.3 0.1 0.22 11.3 0.1 2.7 3 0 0 3 3 3 0 Ring finger domain DUF1524 PF07510.6 ETO02181.1 - 0.0035 17.2 0.5 0.0064 16.3 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) Cytochrom_B562 PF07361.6 ETO02181.1 - 0.071 13.5 0.9 0.17 12.3 0.6 1.6 1 0 0 1 1 1 0 Cytochrome b562 DUF4239 PF14023.1 ETO02181.1 - 0.15 11.4 0.5 0.25 10.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Zn_ribbon_2 PF12674.2 ETO02181.1 - 3.4 8.0 5.4 3.7 7.9 0.5 2.8 3 0 0 3 3 3 0 Putative zinc ribbon domain rve_3 PF13683.1 ETO02182.1 - 0.053 13.0 1.0 1.2 8.7 0.0 3.1 4 0 0 4 4 4 0 Integrase core domain DUF2120 PF09893.4 ETO02182.1 - 0.055 13.4 0.3 0.055 13.4 0.2 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) NAAA-beta PF15508.1 ETO02182.1 - 0.095 13.0 0.2 4 7.8 0.0 3.2 2 1 2 4 4 4 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF4411 PF14367.1 ETO02182.1 - 0.14 11.8 5.5 0.42 10.2 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4411) Nbl1_Borealin_N PF10444.4 ETO02182.1 - 0.53 9.6 4.7 2.9 7.3 0.4 3.3 4 0 0 4 4 4 0 Nbl1 / Borealin N terminal Ank_2 PF12796.2 ETO02183.1 - 4.3e-06 26.9 0.5 2e-05 24.8 0.3 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) ELYS PF13934.1 ETO02183.1 - 1.4e-05 24.9 0.2 1.9e-05 24.5 0.1 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly Ank_4 PF13637.1 ETO02183.1 - 0.0067 16.9 0.4 0.19 12.2 0.0 2.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO02183.1 - 0.024 14.8 0.7 31 5.1 0.0 3.9 4 0 0 4 4 4 0 Ankyrin repeat vWA-TerF-like PF10138.4 ETO02183.1 - 0.053 13.3 0.0 0.066 13.0 0.0 1.1 1 0 0 1 1 1 0 vWA found in TerF C terminus WD40 PF00400.27 ETO02184.1 - 2.7e-72 236.2 18.6 1.1e-14 53.6 0.1 5.6 6 0 0 6 6 6 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO02184.1 - 2.8e-10 39.0 1.8 0.00019 19.8 0.2 2.6 1 1 2 3 3 3 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO02184.1 - 8.4e-09 35.2 0.2 0.0028 17.1 0.0 3.2 1 1 1 3 3 3 3 PQQ-like domain Nup160 PF11715.3 ETO02184.1 - 4.7e-08 31.6 6.3 0.09 10.8 0.7 4.5 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Gmad1 PF10647.4 ETO02184.1 - 0.00053 19.4 1.0 0.24 10.7 0.2 3.3 1 1 1 2 2 2 2 Lipoprotein LpqB beta-propeller domain Rpn3_C PF08375.6 ETO02184.1 - 0.0013 19.1 0.0 7.2 7.0 0.0 4.4 4 1 1 5 5 5 1 Proteasome regulatory subunit C-terminal DUF1258 PF06869.7 ETO02184.1 - 0.0032 16.6 0.4 4.3 6.3 0.0 3.7 1 1 2 4 4 4 1 Protein of unknown function (DUF1258) BLUF PF04940.7 ETO02184.1 - 0.0034 17.0 0.0 10 5.9 0.0 3.8 3 2 1 4 4 4 0 Sensors of blue-light using FAD DUF4275 PF14101.1 ETO02184.1 - 0.0057 16.7 0.0 1 9.4 0.0 3.0 1 1 2 3 3 3 1 Domain of unknown function (DUF4275) NYD-SP28_assoc PF14775.1 ETO02184.1 - 0.0087 15.7 0.3 1.5 8.5 0.0 3.9 5 0 0 5 5 5 1 Sperm tail C-terminal domain ASCH PF04266.9 ETO02184.1 - 0.026 14.9 0.0 13 6.2 0.0 3.6 4 0 0 4 4 4 0 ASCH domain DPPIV_N PF00930.16 ETO02184.1 - 0.026 13.1 1.8 15 3.9 0.0 3.7 1 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.7 ETO02184.1 - 0.048 13.3 1.1 12 5.6 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat TolB_N PF04052.8 ETO02184.1 - 0.12 12.4 0.0 39 4.3 0.0 3.9 5 0 0 5 5 4 0 TolB amino-terminal domain Proteasome_A_N PF10584.4 ETO02184.1 - 3.2 7.1 8.7 19 4.6 0.1 4.2 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature TPR_12 PF13424.1 ETO02185.1 - 4.7e-34 116.1 4.6 2.9e-19 68.7 0.1 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO02185.1 - 4.2e-25 87.1 25.9 1.1e-11 44.1 0.7 3.6 1 1 3 4 4 4 4 TPR repeat TPR_1 PF00515.23 ETO02185.1 - 1.3e-17 62.5 19.1 2.4e-06 26.9 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO02185.1 - 1e-16 59.4 12.5 0.00011 21.8 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO02185.1 - 4.8e-15 54.0 4.3 4.1e-05 23.0 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO02185.1 - 9.8e-13 47.5 0.0 5.8e-06 26.0 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO02185.1 - 3e-10 39.1 21.5 0.0013 18.4 1.3 4.9 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO02185.1 - 7.1e-07 29.7 0.0 0.0027 18.3 0.0 3.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO02185.1 - 1.7e-06 28.0 0.4 1.1 9.8 0.0 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO02185.1 - 2e-06 27.8 9.9 0.0046 17.0 3.6 2.9 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 ETO02185.1 - 0.00022 21.1 1.5 0.67 10.2 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO02185.1 - 0.0016 18.7 1.2 2.5 8.4 0.1 3.1 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO02185.1 - 0.0071 16.8 0.0 81 4.2 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO02185.1 - 0.034 13.4 0.3 16 4.8 0.0 3.4 3 0 0 3 3 3 0 SHNi-TPR Lipase_GDSL_3 PF14606.1 ETO02185.1 - 0.043 13.5 3.1 3.2 7.4 0.0 2.6 3 0 0 3 3 2 0 GDSL-like Lipase/Acylhydrolase family MIT PF04212.13 ETO02185.1 - 0.45 10.4 11.8 9 6.2 0.6 4.7 5 1 0 5 5 5 0 MIT (microtubule interacting and transport) domain DUF627 PF04781.7 ETO02185.1 - 0.52 9.9 7.9 7.5 6.2 0.0 4.2 2 1 3 5 5 5 0 Protein of unknown function (DUF627) SPO22 PF08631.5 ETO02185.1 - 1.4 7.9 8.5 3.4 6.6 0.5 3.0 3 1 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like Phage_Treg PF04761.7 ETO02185.1 - 2.6 7.9 5.9 1.9 8.2 0.1 3.5 3 1 1 4 4 4 0 Lactococcus bacteriophage putative transcription regulator Fis1_TPR_C PF14853.1 ETO02185.1 - 4.7 7.1 10.7 30 4.5 0.8 4.3 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat WD40 PF00400.27 ETO02186.1 - 6.8e-09 35.2 1.1 5.1e-08 32.5 0.1 2.4 2 1 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO02186.1 - 0.1 10.6 0.0 0.11 10.6 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DHquinase_II PF01220.14 ETO02187.1 - 0.065 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Dehydroquinase class II TORC_M PF12885.2 ETO02187.1 - 0.26 11.0 1.0 0.53 10.0 0.7 1.6 1 1 0 1 1 1 0 Transducer of regulated CREB activity middle domain PBD PF00786.23 ETO02189.1 - 0.0014 18.9 0.1 0.021 15.2 0.0 2.3 2 0 0 2 2 2 1 P21-Rho-binding domain PUB PF09409.5 ETO02190.1 - 0.018 14.8 0.4 0.094 12.4 0.3 2.0 1 1 0 1 1 1 0 PUB domain UPF0122 PF04297.9 ETO02190.1 - 0.032 14.2 2.6 0.71 9.9 0.4 2.1 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like TPR_12 PF13424.1 ETO02191.1 - 1.9e-15 56.5 1.0 4.9e-10 39.1 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO02191.1 - 1.2e-12 46.8 1.9 2.3e-05 23.8 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO02191.1 - 1.3e-10 40.7 0.1 3e-10 39.5 0.1 1.6 1 0 0 1 1 1 1 TPR repeat TPR_8 PF13181.1 ETO02191.1 - 2.3e-09 36.3 3.2 0.0005 19.6 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO02191.1 - 1.8e-08 33.6 0.3 0.0024 17.6 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO02191.1 - 4.9e-07 29.0 0.0 0.00023 20.7 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETO02191.1 - 0.00024 20.9 0.0 0.26 11.2 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO02191.1 - 0.0021 18.0 2.7 1.2 9.4 0.0 4.2 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO02191.1 - 0.022 15.1 0.1 7.9 7.1 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETO02191.1 - 0.04 14.5 0.0 0.072 13.7 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO02191.1 - 0.042 13.7 0.1 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.1 ETO02191.1 - 0.11 13.1 0.0 6.2 7.7 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETO02191.1 - 0.12 12.7 0.1 0.41 11.0 0.0 1.9 2 1 0 2 2 2 0 Tetratricopeptide repeat BOF PF04076.8 ETO02192.1 - 0.0059 16.4 0.3 0.0092 15.7 0.2 1.4 1 0 0 1 1 1 1 Bacterial OB fold (BOF) protein DUF3887 PF13026.1 ETO02192.1 - 0.015 15.5 2.3 0.027 14.7 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3887) TPR_12 PF13424.1 ETO02193.1 - 1.2e-50 169.2 12.1 2.5e-17 62.5 0.2 3.6 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.23 ETO02193.1 - 6e-19 66.7 12.2 2.3e-07 30.1 0.2 4.9 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO02193.1 - 3.4e-18 65.0 1.1 2.5e-06 27.0 0.0 3.6 3 0 0 3 3 3 3 TPR repeat TPR_7 PF13176.1 ETO02193.1 - 5.6e-17 60.1 1.9 0.0018 17.9 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO02193.1 - 3.4e-16 57.7 4.5 0.014 15.1 0.0 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO02193.1 - 9e-16 57.2 0.0 9.7e-05 22.1 0.0 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO02193.1 - 2.8e-14 51.7 2.7 0.0032 17.2 0.1 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO02193.1 - 2.3e-05 24.9 0.0 0.78 10.5 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO02193.1 - 3.5e-05 23.6 1.6 0.054 13.7 0.1 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat MIT PF04212.13 ETO02193.1 - 9.2e-05 22.2 0.8 4.7 7.1 0.1 4.4 4 0 0 4 4 4 2 MIT (microtubule interacting and transport) domain TPR_14 PF13428.1 ETO02193.1 - 0.0006 20.2 0.0 69 4.5 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO02193.1 - 0.0018 18.5 0.9 18 6.0 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETO02193.1 - 0.018 15.3 0.2 3.7 7.9 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.7 ETO02193.1 - 1.7 8.5 11.8 2.7 7.8 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat WD40 PF00400.27 ETO02194.1 - 1.1e-56 186.8 18.6 8.8e-11 41.2 0.2 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO02194.1 - 1.3e-10 40.1 5.1 0.002 16.3 0.0 5.6 3 2 2 5 5 5 4 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO02194.1 - 0.053 13.7 8.1 9.3 6.6 0.1 4.8 5 0 0 5 5 5 0 Kelch motif Nucleoporin_N PF08801.6 ETO02194.1 - 0.31 9.7 9.6 6.6 5.3 0.0 4.5 2 1 1 4 4 4 0 Nup133 N terminal like WD40 PF00400.27 ETO02195.1 - 5e-40 133.9 17.2 5.6e-14 51.4 0.3 5.6 5 1 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO02195.1 - 0.039 12.0 0.1 0.73 7.8 0.0 2.4 2 1 0 2 2 2 0 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO02196.1 - 6.2e-06 26.4 2.1 6.2e-06 26.4 1.5 3.1 3 1 2 5 5 5 1 TRAF-type zinc finger Sec8_exocyst PF04048.9 ETO02196.1 - 0.013 15.0 1.7 0.013 15.0 1.1 2.1 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain zf-C3HC4_2 PF13923.1 ETO02196.1 - 0.017 15.1 1.3 0.017 15.1 0.9 3.5 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) RGS PF00615.14 ETO02196.1 - 0.063 13.3 8.2 0.029 14.4 1.7 2.5 1 1 1 2 2 2 0 Regulator of G protein signaling domain zf-H2C2_5 PF13909.1 ETO02196.1 - 7.5 6.9 6.9 44 4.5 0.1 4.5 4 1 1 5 5 5 0 C2H2-type zinc-finger domain Acyl-CoA_dh_C PF12806.2 ETO02198.1 - 0.065 13.1 0.1 0.094 12.5 0.0 1.2 1 0 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like zf-TRAF PF02176.13 ETO02199.1 - 1.4e-06 28.5 4.5 1.4e-06 28.5 3.1 2.1 2 0 0 2 2 2 1 TRAF-type zinc finger zf-RING_2 PF13639.1 ETO02199.1 - 0.44 10.4 9.9 3.1 7.7 0.0 3.3 2 1 0 2 2 2 0 Ring finger domain PHA_synth_III_E PF09712.5 ETO02201.1 - 0.058 12.7 0.1 0.074 12.4 0.0 1.1 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) RGS-like PF09128.6 ETO02202.1 - 0.053 13.0 1.0 0.071 12.5 0.7 1.2 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Chordopox_A33R PF05966.7 ETO02202.1 - 0.83 8.3 4.4 0.99 8.1 3.1 1.1 1 0 0 1 1 1 0 Chordopoxvirus A33R protein PhoQ_Sensor PF08918.5 ETO02203.1 - 0.13 11.7 1.8 0.18 11.3 0.4 1.8 1 1 0 2 2 2 0 PhoQ Sensor WD40 PF00400.27 ETO02204.1 - 2.2e-08 33.6 0.0 1.8e-05 24.4 0.0 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO02204.1 - 0.036 12.1 0.3 0.12 10.4 0.0 1.7 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Ank PF00023.25 ETO02205.1 - 0.0004 20.0 0.0 2.2 8.2 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 ETO02205.1 - 0.00065 19.9 0.1 0.092 13.0 0.0 2.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO02205.1 - 0.0033 17.8 0.1 1.4 9.4 0.0 3.5 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Urm1 PF09138.6 ETO02205.1 - 0.0061 16.6 1.6 0.62 10.2 0.1 2.9 2 1 0 2 2 2 1 Urm1 (Ubiquitin related modifier) Ank_5 PF13857.1 ETO02205.1 - 0.026 14.7 0.0 0.36 11.1 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) CENP-B_dimeris PF09026.5 ETO02207.1 - 0.012 15.7 4.8 0.014 15.5 3.3 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 ETO02207.1 - 0.019 14.6 8.3 0.023 14.3 5.8 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Pox_RNA_Pol_19 PF05320.7 ETO02207.1 - 0.02 14.6 2.0 0.021 14.5 1.4 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Vfa1 PF08432.5 ETO02207.1 - 0.03 14.3 6.1 0.03 14.3 4.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Spot_14 PF07084.7 ETO02207.1 - 0.05 13.4 0.9 0.059 13.2 0.6 1.2 1 0 0 1 1 1 0 Thyroid hormone-inducible hepatic protein Spot 14 RAB3GAP2_C PF14656.1 ETO02207.1 - 0.071 11.2 0.4 0.064 11.3 0.3 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus GOLD_2 PF13897.1 ETO02207.1 - 0.073 13.3 1.7 0.078 13.2 1.2 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking RXT2_N PF08595.6 ETO02207.1 - 0.084 12.6 5.7 0.1 12.3 4.0 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF506 PF04720.7 ETO02207.1 - 0.1 12.2 2.0 0.11 12.1 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Myc_N PF01056.13 ETO02207.1 - 0.1 11.7 5.7 0.12 11.5 3.9 1.1 1 0 0 1 1 1 0 Myc amino-terminal region RNase_H2_suC PF08615.6 ETO02207.1 - 0.12 12.2 0.8 0.11 12.3 0.5 1.1 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) FAM176 PF14851.1 ETO02207.1 - 0.21 11.2 5.9 0.25 11.0 4.1 1.1 1 0 0 1 1 1 0 FAM176 family Nucleo_P87 PF07267.6 ETO02207.1 - 0.41 9.2 3.8 0.45 9.1 2.6 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Tim54 PF11711.3 ETO02207.1 - 0.5 8.9 4.5 0.52 8.8 3.1 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.9 ETO02207.1 - 0.6 8.0 7.4 0.57 8.1 5.1 1.0 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.11 ETO02207.1 - 0.67 8.8 6.9 0.77 8.6 4.8 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PBP1_TM PF14812.1 ETO02207.1 - 0.77 10.0 7.2 0.96 9.7 5.0 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tom22 PF04281.8 ETO02207.1 - 0.8 9.2 6.4 0.98 8.9 4.5 1.1 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Pox_Ag35 PF03286.9 ETO02207.1 - 0.88 9.0 9.1 1.1 8.7 6.3 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.7 ETO02207.1 - 0.93 7.3 12.0 1 7.1 8.3 1.0 1 0 0 1 1 1 0 Nop14-like family EBV-NA3 PF05009.7 ETO02207.1 - 1.1 8.5 3.8 1.3 8.2 2.7 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Phage_Gp23 PF10669.4 ETO02207.1 - 1.3 9.0 5.3 1.8 8.7 3.7 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) SMN PF06003.7 ETO02207.1 - 1.9 7.5 4.6 2.1 7.3 3.2 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Sporozoite_P67 PF05642.6 ETO02207.1 - 2 6.2 7.9 2 6.2 5.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Prp19_bind PF06991.6 ETO02207.1 - 2 7.6 13.4 0.16 11.2 4.9 1.9 2 0 0 2 2 2 0 Splicing factor, Prp19-binding domain DUF2890 PF11081.3 ETO02207.1 - 2.2 8.3 11.3 2.6 8.0 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) SspB PF04386.8 ETO02207.1 - 2.2 7.8 6.8 2.6 7.6 4.7 1.1 1 0 0 1 1 1 0 Stringent starvation protein B RRN3 PF05327.6 ETO02207.1 - 2.6 6.0 7.0 2.7 6.0 4.8 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2457 PF10446.4 ETO02207.1 - 2.9 6.5 13.5 3.2 6.3 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Radial_spoke PF04712.7 ETO02207.1 - 3.8 6.1 9.1 4.2 6.0 6.3 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein HSP90 PF00183.13 ETO02207.1 - 5.5 5.2 11.2 6.4 5.0 7.8 1.1 1 0 0 1 1 1 0 Hsp90 protein Nucleoplasmin PF03066.10 ETO02207.1 - 5.9 6.3 16.1 7.8 5.9 11.2 1.1 1 0 0 1 1 1 0 Nucleoplasmin Daxx PF03344.10 ETO02207.1 - 6.6 5.0 14.4 7.1 4.9 10.0 1.0 1 0 0 1 1 1 0 Daxx Family CobT PF06213.7 ETO02207.1 - 6.7 5.7 13.7 7.5 5.5 9.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT S-antigen PF05756.6 ETO02207.1 - 7.4 6.6 11.1 10 6.1 7.7 1.3 1 0 0 1 1 1 0 S-antigen protein TFIIF_alpha PF05793.7 ETO02207.1 - 7.8 4.7 14.6 8.6 4.6 10.1 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DNA_pol_phi PF04931.8 ETO02207.1 - 9.6 3.8 14.0 11 3.6 9.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi WD40 PF00400.27 ETO02208.1 - 1.4e-31 107.1 7.2 1e-09 37.8 0.3 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat IKI3 PF04762.7 ETO02208.1 - 3.6e-05 21.8 0.1 8.1e-05 20.6 0.0 1.7 1 1 0 1 1 1 1 IKI3 family Nup160 PF11715.3 ETO02208.1 - 3.7e-05 22.0 0.5 0.025 12.7 0.1 2.3 2 1 0 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO02208.1 - 0.00016 21.4 0.7 0.0011 18.7 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 ETO02208.1 - 0.0014 17.7 0.9 0.041 12.9 0.1 2.6 1 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Remorin_C PF03763.8 ETO02209.1 - 0.062 12.8 0.9 0.099 12.1 0.6 1.3 1 0 0 1 1 1 0 Remorin, C-terminal region HEAT_2 PF13646.1 ETO02211.1 - 0.00047 20.3 0.1 0.12 12.6 0.0 1.9 1 1 1 2 2 2 2 HEAT repeats DUF4393 PF14337.1 ETO02211.1 - 0.036 13.5 0.3 0.043 13.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4393) Xpo1 PF08389.7 ETO02211.1 - 0.07 13.0 0.0 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 Exportin 1-like protein HEAT_EZ PF13513.1 ETO02211.1 - 0.14 12.7 0.0 1.2 9.7 0.0 2.1 2 0 0 2 2 2 0 HEAT-like repeat HEAT_2 PF13646.1 ETO02212.1 - 9.3e-21 73.9 0.0 6.3e-08 32.7 0.0 4.2 2 2 3 5 5 5 4 HEAT repeats HEAT PF02985.17 ETO02212.1 - 1e-13 50.0 0.0 0.056 13.5 0.0 5.2 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.1 ETO02212.1 - 3.6e-10 40.0 0.0 0.051 14.0 0.0 5.3 3 2 2 5 5 5 4 HEAT-like repeat DUF3554 PF12074.3 ETO02212.1 - 6.7e-06 25.7 5.5 0.00067 19.1 0.1 3.6 2 2 2 4 4 4 2 Domain of unknown function (DUF3554) CLASP_N PF12348.3 ETO02212.1 - 1.7e-05 24.2 0.5 0.031 13.6 0.0 2.7 3 0 0 3 3 3 2 CLASP N terminal Cnd1 PF12717.2 ETO02212.1 - 0.00011 22.1 7.0 0.049 13.4 2.4 3.4 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 DUF3137 PF11335.3 ETO02212.1 - 0.00017 21.2 0.1 0.063 12.9 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3137) DUF3810 PF12725.2 ETO02212.1 - 0.00082 18.3 0.8 0.0036 16.2 0.1 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF3810) Vac14_Fab1_bd PF12755.2 ETO02212.1 - 0.0018 18.6 7.9 0.53 10.6 0.0 5.2 4 2 2 6 6 6 1 Vacuolar 14 Fab1-binding region TIP120 PF08623.5 ETO02212.1 - 0.0023 17.5 8.8 1 8.9 0.1 4.2 2 2 3 5 5 5 1 TATA-binding protein interacting (TIP20) DUF2435 PF10363.4 ETO02212.1 - 0.0036 17.1 1.4 9.6 6.1 0.0 4.2 2 2 3 5 5 5 0 Protein of unknown function (DUF2435) HEAT_PBS PF03130.11 ETO02212.1 - 0.007 16.7 0.0 8.3 7.2 0.0 4.5 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat NLE PF08154.7 ETO02212.1 - 0.011 15.7 3.8 8.3 6.5 0.0 4.6 4 1 0 4 4 4 0 NLE (NUC135) domain ArgJ PF01960.13 ETO02212.1 - 0.03 12.7 0.2 4.3 5.6 0.0 2.2 1 1 1 2 2 2 0 ArgJ family Syntaphilin PF15290.1 ETO02212.1 - 0.036 13.5 2.1 1.7 8.0 0.2 2.4 1 1 1 2 2 2 0 Golgi-localised syntaxin-1-binding clamp Spore_III_AB PF09548.5 ETO02212.1 - 0.036 13.8 5.0 0.095 12.4 0.9 3.3 3 1 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) RNA_binding PF01877.12 ETO02212.1 - 0.076 13.0 4.7 7.7 6.5 0.1 4.2 1 1 4 5 5 5 0 RNA binding DUF2758 PF10957.3 ETO02212.1 - 0.46 10.3 3.0 18 5.2 0.2 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2758) GatB_Yqey PF02637.13 ETO02212.1 - 1.1 9.0 5.6 3.4 7.3 2.4 2.6 1 1 1 2 2 2 0 GatB domain Utp13 PF08625.6 ETO02212.1 - 3.9 7.1 6.1 2.2 7.9 0.1 3.2 2 1 2 4 4 4 0 Utp13 specific WD40 associated domain MEF2_binding PF09047.5 ETO02213.1 - 0.16 11.6 1.2 0.22 11.1 0.1 1.8 2 0 0 2 2 2 0 MEF2 binding MSC PF09402.5 ETO02217.1 - 9.5e-05 21.2 1.3 0.00011 21.0 0.9 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain YMF19 PF02326.10 ETO02217.1 - 0.011 16.2 5.5 0.017 15.7 3.8 1.2 1 0 0 1 1 1 0 Plant ATP synthase F0 DUF3796 PF12676.2 ETO02217.1 - 0.026 14.7 3.8 0.035 14.3 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) ETRAMP PF09716.5 ETO02217.1 - 0.029 14.3 11.8 0.048 13.6 8.2 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) TORC_M PF12885.2 ETO02217.1 - 0.042 13.6 0.0 0.049 13.3 0.0 1.2 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain Ribosomal_L6e PF01159.14 ETO02217.1 - 0.051 13.8 4.3 0.076 13.2 3.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L6e 7tm_1 PF00001.16 ETO02217.1 - 0.17 10.9 1.1 0.21 10.6 0.7 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DIRP PF06584.8 ETO02217.1 - 0.19 11.5 3.6 0.28 11.0 2.5 1.2 1 0 0 1 1 1 0 DIRP DUF70 PF01901.11 ETO02217.1 - 0.22 10.5 1.9 0.27 10.2 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF70 PDR_CDR PF06422.7 ETO02217.1 - 0.47 10.1 3.5 0.77 9.4 2.4 1.3 1 0 0 1 1 1 0 CDR ABC transporter Protocadherin PF08374.6 ETO02217.1 - 0.6 9.7 3.7 0.75 9.3 2.6 1.1 1 0 0 1 1 1 0 Protocadherin Peptidase_S49_N PF08496.5 ETO02217.1 - 1.2 8.9 6.3 1.6 8.5 4.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Rpn3_C PF08375.6 ETO02218.1 - 0.36 11.2 3.5 2.9 8.3 0.0 2.2 2 0 0 2 2 2 0 Proteasome regulatory subunit C-terminal zf-C3HC4_2 PF13923.1 ETO02219.1 - 0.49 10.4 3.8 1.9 8.5 1.4 2.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO02219.1 - 1.6 8.6 7.3 2.1 8.2 3.0 2.7 2 1 1 3 3 3 0 Ring finger domain TPR_12 PF13424.1 ETO02220.1 - 5.7e-33 112.7 11.8 5.3e-18 64.7 0.3 3.3 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO02220.1 - 3e-11 42.8 11.4 0.00012 21.6 0.6 3.4 3 0 0 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETO02220.1 - 8.4e-11 41.0 16.0 0.00041 19.8 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO02220.1 - 4.4e-10 38.5 3.4 0.0015 18.1 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO02220.1 - 2.1e-09 36.5 14.9 0.00062 19.4 0.1 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO02220.1 - 1.6e-08 34.1 1.4 0.0016 18.3 0.0 3.9 5 0 0 5 5 5 2 Tetratricopeptide repeat MIT PF04212.13 ETO02220.1 - 0.00068 19.4 2.9 0.096 12.5 0.4 2.8 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_8 PF13181.1 ETO02220.1 - 0.0036 16.9 15.5 0.97 9.3 0.1 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO02220.1 - 0.034 14.3 0.9 16 5.9 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETO02220.1 - 0.11 13.2 0.0 6.7 7.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TSA PF03249.8 ETO02221.1 - 5.6 5.3 8.0 5.9 5.3 5.5 1.1 1 0 0 1 1 1 0 Type specific antigen U-box PF04564.10 ETO02222.1 - 1.6e-14 53.5 0.0 3.6e-14 52.4 0.0 1.6 1 1 0 1 1 1 1 U-box domain zf-Nse PF11789.3 ETO02222.1 - 0.13 11.7 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit SAM_2 PF07647.12 ETO02223.1 - 0.0035 17.1 0.4 0.0099 15.7 0.3 1.8 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 ETO02223.1 - 0.1 12.3 0.2 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain WD40 PF00400.27 ETO02225.1 - 4.1e-55 181.7 8.3 2e-12 46.4 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO02225.1 - 5.1e-08 31.4 4.1 0.0087 14.2 0.0 4.1 2 2 2 4 4 4 3 Nucleoporin Nup120/160 Resistin PF06954.6 ETO02225.1 - 3e-05 24.2 0.7 3.5 7.9 0.0 4.0 2 2 2 4 4 4 2 Resistin PD40 PF07676.7 ETO02225.1 - 0.00062 19.3 5.1 30 4.4 0.0 5.9 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.9 ETO02225.1 - 0.0051 15.6 2.5 0.0054 15.5 0.3 2.2 2 1 0 2 2 2 1 Coatomer WD associated region Cytochrom_D1 PF02239.11 ETO02225.1 - 0.011 14.0 0.2 0.7 8.1 0.0 2.4 1 1 1 2 2 2 0 Cytochrome D1 heme domain PSII_BNR PF14870.1 ETO02225.1 - 0.011 14.7 0.1 2.7 6.9 0.0 2.9 1 1 2 3 3 3 0 Photosynthesis system II assembly factor YCF48 PQQ_2 PF13360.1 ETO02225.1 - 0.019 14.4 0.0 0.11 11.9 0.0 2.1 1 1 0 1 1 1 0 PQQ-like domain Herpes_U15 PF05613.6 ETO02225.1 - 0.11 12.8 1.0 0.29 11.5 0.7 1.8 1 1 0 1 1 1 0 Human herpesvirus U15 protein DUF387 PF04079.11 ETO02226.1 - 0.091 12.1 0.6 0.098 12.0 0.4 1.0 1 0 0 1 1 1 0 Putative transcriptional regulators (Ypuh-like) DUF3899 PF13038.1 ETO02226.1 - 0.31 11.2 4.0 0.13 12.4 0.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) TMPIT PF07851.8 ETO02226.1 - 1.8 7.5 6.2 2.2 7.2 4.3 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF4254 PF14063.1 ETO02227.1 - 0.1 12.2 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) Staphopain_pro PF14731.1 ETO02227.1 - 0.13 12.0 1.3 0.16 11.7 0.4 1.5 1 1 1 2 2 2 0 Staphopain proregion Colipase-like PF15083.1 ETO02227.1 - 0.2 11.5 3.8 0.66 9.9 2.7 1.9 1 1 0 1 1 1 0 Colipase-like DUF960 PF06124.6 ETO02230.1 - 0.014 15.5 2.9 0.023 14.9 1.6 1.8 2 1 0 2 2 2 0 Staphylococcal protein of unknown function (DUF960) Cauli_AT PF03233.8 ETO02231.1 - 0.095 12.3 1.4 0.11 12.2 1.0 1.1 1 0 0 1 1 1 0 Aphid transmission protein Viral_Beta_CD PF04530.7 ETO02233.1 - 0.039 14.0 0.2 0.047 13.8 0.1 1.1 1 0 0 1 1 1 0 Viral Beta C/D like family NicO PF03824.11 ETO02234.1 - 0.28 10.4 2.6 0.55 9.4 1.8 1.4 1 0 0 1 1 1 0 High-affinity nickel-transport protein SelP_N PF04592.9 ETO02234.1 - 7.5 5.8 18.3 0.14 11.4 7.0 2.3 2 0 0 2 2 2 0 Selenoprotein P, N terminal region PNPase PF03726.9 ETO02238.1 - 0.0043 17.2 0.1 0.0059 16.8 0.1 1.2 1 0 0 1 1 1 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain Glucosamine_iso PF01182.15 ETO02240.1 - 0.099 12.3 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PBP_GOBP PF01395.17 ETO02241.1 - 0.1 12.2 0.7 1.3 8.6 0.1 2.1 1 1 1 2 2 2 0 PBP/GOBP family DUF1778 PF08681.6 ETO02242.1 - 0.14 11.9 0.1 0.39 10.5 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1778) DUF501 PF04417.7 ETO02244.1 - 2 8.2 5.2 1.6 8.5 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF501) IQ-like PF15157.1 ETO02244.1 - 6.8 6.9 9.9 0.93 9.7 1.3 2.7 1 1 1 2 2 2 0 IQ-like SecA_DEAD PF07517.9 ETO02244.1 - 7.1 5.8 12.0 5.4e+02 -0.4 8.3 2.1 1 1 0 1 1 1 0 SecA DEAD-like domain U-box PF04564.10 ETO02245.1 - 1.9e-11 43.7 0.0 5e-11 42.4 0.0 1.7 1 1 0 1 1 1 1 U-box domain Ste50p-SAM PF09235.5 ETO02245.1 - 0.1 12.6 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Ste50p, sterile alpha motif WD40 PF00400.27 ETO02246.1 - 4.2e-23 80.3 3.6 9.4e-11 41.1 0.1 3.5 3 1 0 3 3 3 3 WD domain, G-beta repeat WD40 PF00400.27 ETO02247.1 - 2.4e-19 68.4 0.5 5.5e-12 45.0 0.0 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO02247.1 - 0.00078 17.7 0.1 0.00081 17.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin Nup120/160 DUF851 PF05867.6 ETO02247.1 - 0.012 14.8 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF851) ABC2_membrane_3 PF12698.2 ETO02248.1 - 0.14 11.1 1.2 0.15 11.0 0.8 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein FAM176 PF14851.1 ETO02249.1 - 0.11 12.1 0.7 0.16 11.6 0.5 1.2 1 0 0 1 1 1 0 FAM176 family DUF4611 PF15387.1 ETO02249.1 - 0.18 11.9 2.6 0.26 11.4 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 ETO02249.1 - 0.19 11.2 4.4 0.29 10.6 3.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 ETO02249.1 - 1 9.6 6.6 1.6 9.0 4.6 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 ETO02249.1 - 2.8 8.3 10.3 0.068 13.4 2.0 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ank_2 PF12796.2 ETO02251.1 - 1.9e-10 40.9 0.1 4.5e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO02251.1 - 1.1e-09 37.5 0.1 0.00022 21.1 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 ETO02251.1 - 1.6e-09 37.9 0.4 6.5e-08 32.8 0.1 2.7 3 0 0 3 3 2 1 Ankyrin repeats (many copies) Ank PF00023.25 ETO02251.1 - 3.8e-07 29.5 0.0 9.1e-05 22.0 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 ETO02251.1 - 5.1e-07 29.7 2.0 3.5e-05 23.8 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) HEAT_2 PF13646.1 ETO02251.1 - 0.00066 19.9 0.0 0.026 14.7 0.0 2.6 2 0 0 2 2 2 1 HEAT repeats Activator-TraM PF11657.3 ETO02251.1 - 0.0011 18.4 5.4 0.55 9.6 0.1 3.1 3 0 0 3 3 3 2 Transcriptional activator TraM DUF3554 PF12074.3 ETO02251.1 - 0.0031 17.0 1.4 0.019 14.4 0.9 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3554) HEAT PF02985.17 ETO02251.1 - 0.0063 16.5 0.0 0.03 14.4 0.0 2.3 1 0 0 1 1 1 1 HEAT repeat DUF2808 PF10989.3 ETO02251.1 - 0.025 14.1 0.0 0.073 12.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) NLE PF08154.7 ETO02251.1 - 0.031 14.2 4.5 4.3 7.4 0.1 3.8 3 1 0 4 4 4 0 NLE (NUC135) domain Fe-S_assembly PF04384.8 ETO02251.1 - 0.068 13.5 7.1 0.81 10.0 0.2 4.0 5 0 0 5 5 3 0 Iron-sulphur cluster assembly DUF1843 PF08898.5 ETO02251.1 - 0.14 12.2 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) DUF4284 PF14112.1 ETO02251.1 - 0.49 10.8 10.3 0.23 11.9 0.2 3.3 4 0 0 4 4 3 0 Domain of unknown function (DUF4284) Perilipin PF03036.11 ETO02252.1 - 0.00017 20.5 3.1 0.00018 20.4 2.2 1.0 1 0 0 1 1 1 1 Perilipin family Adaptin_binding PF10199.4 ETO02252.1 - 0.038 14.2 6.4 0.05 13.8 4.4 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 POX PF07526.6 ETO02252.1 - 0.069 13.3 1.4 0.085 13.0 0.9 1.2 1 0 0 1 1 1 0 Associated with HOX DUF4196 PF13846.1 ETO02252.1 - 0.088 13.1 6.6 0.11 12.8 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4196) Pox_RNA_Pol_19 PF05320.7 ETO02252.1 - 0.1 12.3 6.6 0.13 12.0 4.6 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Baculo_LEF-2 PF03041.9 ETO02252.1 - 0.21 11.2 2.0 0.27 10.8 1.4 1.1 1 0 0 1 1 1 0 lef-2 CENP-R PF06729.7 ETO02252.1 - 0.21 11.2 5.5 0.27 10.9 3.8 1.1 1 0 0 1 1 1 0 Kinetochore component, CENP-R DUF2894 PF11445.3 ETO02252.1 - 0.28 11.4 3.3 0.34 11.1 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) IncA PF04156.9 ETO02252.1 - 0.76 9.3 14.1 0.92 9.0 9.8 1.2 1 0 0 1 1 1 0 IncA protein DUF506 PF04720.7 ETO02252.1 - 1.1 8.8 5.1 1.2 8.6 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF506) S-antigen PF05756.6 ETO02252.1 - 2.3 8.2 10.7 3.7 7.5 7.4 1.3 1 0 0 1 1 1 0 S-antigen protein Vps51 PF08700.6 ETO02252.1 - 5 7.0 11.0 0.58 10.0 0.3 2.8 3 0 0 3 3 3 0 Vps51/Vps67 Bap31 PF05529.7 ETO02252.1 - 6.7 6.1 9.4 9.7 5.6 6.5 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DivIC PF04977.10 ETO02252.1 - 9.7 5.7 14.1 0.49 9.9 1.2 2.9 1 1 2 3 3 3 0 Septum formation initiator WD40 PF00400.27 ETO02254.1 - 4.3e-15 54.9 0.4 4.6e-09 35.8 0.0 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF1900 PF08954.6 ETO02254.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1900) Tubulin_C PF03953.12 ETO02255.1 - 1.3e-28 99.6 0.1 1.7e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Tubulin C-terminal domain PerB PF06590.6 ETO02255.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 PerB protein Kelch_4 PF13418.1 ETO02256.1 - 0.00015 21.4 0.0 0.2 11.4 0.0 2.5 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO02256.1 - 0.00087 18.7 3.1 0.0046 16.4 0.1 2.7 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 ETO02256.1 - 0.0015 18.6 0.7 0.26 11.5 0.1 2.8 1 1 1 2 2 2 2 Kelch motif Kelch_2 PF07646.10 ETO02256.1 - 0.0022 17.7 0.2 1.7 8.5 0.1 2.9 3 0 0 3 3 3 2 Kelch motif PUB PF09409.5 ETO02258.1 - 0.00054 19.6 1.0 0.0017 18.0 0.7 1.8 1 1 0 1 1 1 1 PUB domain DUF2871 PF11070.3 ETO02258.1 - 0.053 13.6 1.5 0.052 13.7 0.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2871) PIF1 PF05970.9 ETO02258.1 - 0.1 11.5 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase DUF4557 PF15101.1 ETO02260.1 - 0.56 10.0 5.7 1.2 8.9 3.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4557) zf-C3HC4_2 PF13923.1 ETO02260.1 - 3.3 7.8 9.0 0.81 9.7 1.4 2.9 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RNase_H PF00075.19 ETO02261.1 - 0.00023 21.5 0.0 0.00027 21.2 0.0 1.2 1 0 0 1 1 1 1 RNase H Kelch_6 PF13964.1 ETO02263.1 - 3.8e-07 29.9 2.8 0.008 16.3 0.1 3.9 2 1 1 3 3 3 2 Kelch motif Kelch_1 PF01344.20 ETO02263.1 - 0.00016 21.1 7.2 0.046 13.2 1.1 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 ETO02263.1 - 0.00017 21.2 0.9 0.089 12.5 0.2 3.1 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 ETO02263.1 - 0.00083 19.4 0.0 0.045 13.9 0.0 2.9 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO02263.1 - 0.0039 16.9 0.1 0.23 11.2 0.0 2.8 2 0 0 2 2 2 1 Galactose oxidase, central domain IBR PF01485.16 ETO02263.1 - 0.016 15.0 6.3 0.016 15.0 4.4 4.6 4 0 0 4 4 4 0 IBR domain Kelch_5 PF13854.1 ETO02263.1 - 0.14 12.1 8.4 14 5.7 0.5 4.5 5 0 0 5 5 5 0 Kelch motif zf-RING_4 PF14570.1 ETO02263.1 - 4.2 7.0 13.0 7 6.3 2.5 3.4 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain CLTH PF10607.4 ETO02264.1 - 0.46 10.1 5.9 0.84 9.3 4.1 1.5 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain PPR_2 PF13041.1 ETO02265.1 - 1.2e-14 54.0 4.2 1e-08 35.0 0.1 3.3 3 0 0 3 3 3 2 PPR repeat family PPR PF01535.15 ETO02265.1 - 3.7e-14 51.6 5.1 0.00019 21.1 0.0 4.4 4 0 0 4 4 4 4 PPR repeat PPR_3 PF13812.1 ETO02265.1 - 9.5e-13 47.3 0.1 6.4e-05 22.9 0.0 4.4 4 0 0 4 4 4 3 Pentatricopeptide repeat domain PPR_1 PF12854.2 ETO02265.1 - 1.1e-08 34.4 0.6 0.00078 18.8 0.0 3.6 4 0 0 4 4 4 3 PPR repeat DUF3636 PF12331.3 ETO02265.1 - 0.012 15.1 0.0 0.022 14.3 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3636) ATP13 PF12921.2 ETO02265.1 - 0.17 11.2 1.3 0.76 9.1 0.1 2.5 1 1 1 3 3 3 0 Mitochondrial ATPase expression SAP PF02037.22 ETO02266.1 - 3.2e-05 23.3 0.1 5.5e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 SAP domain Pex14_N PF04695.8 ETO02266.1 - 1.4 8.9 13.5 0.4 10.7 0.5 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region BTV_NS2 PF04514.7 ETO02268.1 - 2.1 7.1 13.7 2.9 6.6 9.5 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 IncA PF04156.9 ETO02268.1 - 7.6 6.0 11.2 13 5.3 7.8 1.3 1 0 0 1 1 1 0 IncA protein Peptidase_S49_N PF08496.5 ETO02268.1 - 9.9 5.9 8.6 19 5.0 5.9 1.6 1 1 0 1 1 1 0 Peptidase family S49 N-terminal PI3_PI4_kinase PF00454.22 ETO02269.1 - 1.5e-37 129.3 0.1 4.2e-37 127.8 0.1 1.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase WD40 PF00400.27 ETO02270.1 - 1.3e-20 72.4 0.3 1.5e-10 40.5 0.1 3.6 4 0 0 4 4 4 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO02270.1 - 0.086 10.9 0.1 0.7 7.9 0.0 1.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Glyco_hydro_18 PF00704.23 ETO02271.1 - 2.4e-20 73.2 1.9 4.7e-20 72.3 1.3 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 AAA_4 PF04326.9 ETO02271.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.6 1 1 0 1 1 1 0 Divergent AAA domain FMO-like PF00743.14 ETO02273.1 - 0.05 11.7 0.3 0.056 11.6 0.2 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like UPF0180 PF03698.8 ETO02273.1 - 0.057 13.2 0.1 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) DnaJ PF00226.26 ETO02274.1 - 1.2e-09 37.6 1.7 1.7e-09 37.2 1.0 1.4 1 1 0 1 1 1 1 DnaJ domain DUF2039 PF10217.4 ETO02274.1 - 6.4e-05 22.9 1.9 7.8e-05 22.6 1.3 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) Geminin PF07412.7 ETO02275.1 - 0.03 14.0 4.8 0.03 14.0 3.4 2.6 2 2 0 2 2 2 0 Geminin HSCB_C PF07743.8 ETO02275.1 - 0.11 13.0 10.6 1.8 9.0 0.8 2.6 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain DUF4140 PF13600.1 ETO02275.1 - 6.3 7.3 6.8 15 6.1 0.5 2.5 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) MMR_HSR1 PF01926.18 ETO02276.1 - 9.7e-06 25.5 0.0 6.4e-05 22.8 0.0 2.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 ETO02276.1 - 6.4e-05 22.1 0.9 0.00055 19.1 0.2 2.8 2 1 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 ETO02276.1 - 0.00061 20.0 0.0 0.00061 20.0 0.0 2.9 3 1 1 4 4 4 1 ABC transporter AAA_29 PF13555.1 ETO02276.1 - 0.0055 16.2 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Miro PF08477.8 ETO02276.1 - 0.0086 16.5 0.4 0.064 13.7 0.1 2.6 1 1 1 2 2 2 1 Miro-like protein AAA_16 PF13191.1 ETO02276.1 - 0.011 15.6 0.1 0.5 10.3 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 ETO02276.1 - 0.029 13.7 0.0 0.068 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 ETO02276.1 - 0.042 13.9 0.7 0.35 10.9 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 ETO02276.1 - 0.1 12.5 0.5 0.34 10.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 ETO02276.1 - 4.9 7.4 8.9 5.1 7.4 0.1 3.7 3 1 0 3 3 3 0 AAA domain ATG2_CAD PF13329.1 ETO02277.1 - 0.0018 17.9 4.6 0.0057 16.2 1.4 2.7 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif Acyl-CoA_dh_C PF12806.2 ETO02277.1 - 0.021 14.6 0.7 3.9 7.3 0.0 3.4 2 2 2 4 4 4 0 Acetyl-CoA dehydrogenase C-terminal like Peptidase_S39 PF02122.10 ETO02277.1 - 0.071 12.4 2.0 0.13 11.5 1.4 1.4 1 0 0 1 1 1 0 Peptidase S39 DUF480 PF04337.7 ETO02277.1 - 0.7 9.7 8.3 0.48 10.2 0.1 3.4 1 1 2 3 3 3 0 Protein of unknown function, DUF480 CLP_protease PF00574.18 ETO02277.1 - 0.72 9.4 5.0 0.29 10.7 0.1 2.6 2 1 1 3 3 3 0 Clp protease DUF1192 PF06698.6 ETO02277.1 - 3.5 7.4 8.8 2.6 7.9 0.1 4.0 2 2 1 3 3 3 0 Protein of unknown function (DUF1192) DUF4277 PF14104.1 ETO02278.1 - 0.0097 16.0 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4277) DHC PF09626.5 ETO02278.1 - 0.053 14.1 0.5 0.12 13.0 0.1 1.8 1 1 0 1 1 1 0 Dihaem cytochrome c DUF3606 PF12244.3 ETO02278.1 - 0.11 12.1 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) TPR_12 PF13424.1 ETO02279.1 - 1.9e-28 98.1 10.8 1.9e-23 82.1 1.8 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO02279.1 - 5.3e-24 83.6 17.6 1.8e-08 33.9 0.2 3.0 3 0 0 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETO02279.1 - 1.5e-22 78.1 27.4 1.6e-09 36.9 1.7 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO02279.1 - 6.1e-22 75.7 16.4 2.9e-08 33.0 0.8 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO02279.1 - 7e-17 60.7 5.5 1.3e-06 28.1 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO02279.1 - 1.9e-16 60.2 5.6 8.1e-08 32.7 0.0 2.3 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO02279.1 - 7.8e-15 53.4 7.2 5.6e-06 25.7 0.1 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO02279.1 - 1.1e-13 50.4 0.0 0.0049 17.3 0.0 3.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO02279.1 - 1.5e-13 49.4 26.9 3.3e-06 26.4 1.6 4.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO02279.1 - 1.4e-11 44.0 4.5 0.0016 18.7 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO02279.1 - 6.6e-09 35.9 2.7 0.00013 22.1 0.8 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat SNAP PF14938.1 ETO02279.1 - 7.4e-08 31.8 5.9 8.9e-08 31.6 4.1 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP Apc3 PF12895.2 ETO02279.1 - 9.8e-08 32.0 15.5 0.00038 20.5 7.0 2.9 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 ETO02279.1 - 3.9e-07 29.1 1.4 0.0014 17.8 0.1 3.3 3 0 0 3 3 3 1 SHNi-TPR TPR_17 PF13431.1 ETO02279.1 - 1.9e-06 27.5 22.8 0.018 15.2 0.1 4.7 4 2 0 4 4 4 3 Tetratricopeptide repeat RPN7 PF10602.4 ETO02279.1 - 4.3e-06 26.2 6.5 0.015 14.6 0.1 3.0 1 1 2 3 3 3 2 26S proteasome subunit RPN7 MIT PF04212.13 ETO02279.1 - 5.9e-06 26.0 11.6 0.028 14.2 0.9 3.1 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain PPR PF01535.15 ETO02279.1 - 9e-05 22.1 3.0 0.21 11.6 0.1 3.4 3 0 0 3 3 3 1 PPR repeat DUF2225 PF09986.4 ETO02279.1 - 9.1e-05 22.0 11.2 0.00023 20.7 3.1 2.0 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) Prefoldin PF02996.12 ETO02279.1 - 0.00022 20.8 4.5 0.049 13.2 0.1 2.9 1 1 2 3 3 3 1 Prefoldin subunit TPR_15 PF13429.1 ETO02279.1 - 0.0011 18.1 1.2 0.0015 17.6 0.8 1.3 1 1 0 1 1 1 1 Tetratricopeptide repeat PPR_2 PF13041.1 ETO02279.1 - 0.0016 18.3 2.0 10 6.1 0.0 3.3 3 0 0 3 3 3 0 PPR repeat family TPR_3 PF07720.7 ETO02279.1 - 0.0017 18.0 12.0 0.0041 16.8 0.7 2.7 3 0 0 3 3 2 2 Tetratricopeptide repeat Sec5 PF15469.1 ETO02279.1 - 0.0048 16.6 12.2 0.18 11.4 1.4 2.9 2 1 1 3 3 3 1 Exocyst complex component Sec5 TPR_9 PF13371.1 ETO02279.1 - 0.0065 16.2 0.0 0.22 11.3 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_5 PF12688.2 ETO02279.1 - 0.011 15.7 0.5 0.41 10.7 0.0 2.7 2 1 0 2 2 2 0 Tetratrico peptide repeat Foie-gras_1 PF11817.3 ETO02279.1 - 0.016 14.6 2.7 1.8 7.9 0.3 2.4 1 1 0 2 2 2 0 Foie gras liver health family 1 Sel1 PF08238.7 ETO02279.1 - 0.024 15.2 8.5 1.4 9.6 0.3 3.3 3 0 0 3 3 3 0 Sel1 repeat Rdx PF10262.4 ETO02279.1 - 0.06 13.3 3.3 16 5.6 2.3 2.9 1 1 0 1 1 1 0 Rdx family NSF PF02071.15 ETO02279.1 - 0.075 13.5 10.0 7 7.7 0.2 4.4 4 0 0 4 4 3 0 Aromatic-di-Alanine (AdAR) repeat DUF424 PF04242.8 ETO02279.1 - 0.12 12.4 0.9 0.86 9.6 0.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF424) DUF3014 PF11219.3 ETO02279.1 - 0.25 11.1 1.7 3.5 7.4 1.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3014) Rapsyn_N PF10579.4 ETO02279.1 - 0.29 10.9 2.7 19 5.1 0.1 3.0 1 1 2 3 3 3 0 Rapsyn N-terminal myristoylation and linker region Mad3_BUB1_I PF08311.7 ETO02279.1 - 0.56 10.0 6.9 5.7 6.7 1.1 2.9 2 1 1 3 3 3 0 Mad3/BUB1 homology region 1 Endonuc-dimeris PF09124.5 ETO02279.1 - 0.84 9.3 3.3 4.1 7.1 0.0 2.6 3 0 0 3 3 3 0 T4 recombination endonuclease VII, dimerisation OEP PF02321.13 ETO02279.1 - 1.1 8.8 9.0 4.7 6.7 4.1 2.8 1 1 2 3 3 3 0 Outer membrane efflux protein SPO22 PF08631.5 ETO02279.1 - 3.2 6.7 11.4 3.5 6.6 0.3 3.0 1 1 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like DUF2989 PF11207.3 ETO02279.1 - 7.9 5.8 12.5 2.5 7.5 0.7 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2989) Fis1_TPR_C PF14853.1 ETO02279.1 - 8.8 6.3 11.0 1.9 8.4 0.7 3.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DUF4366 PF14283.1 ETO02282.1 - 0.019 14.4 4.0 0.024 14.0 2.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) DUF2457 PF10446.4 ETO02282.1 - 0.02 13.6 11.6 0.018 13.8 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 ETO02282.1 - 0.028 13.9 6.0 0.029 13.8 4.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin gpW PF02831.10 ETO02282.1 - 0.064 12.8 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 gpW NOA36 PF06524.7 ETO02282.1 - 1.4 8.0 9.8 1.5 8.0 6.8 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2076 PF09849.4 ETO02282.1 - 5.6 6.9 8.1 6.1 6.8 5.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Ank_2 PF12796.2 ETO02283.1 - 0.0017 18.6 0.1 0.0045 17.3 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO02283.1 - 0.0022 18.4 0.1 0.035 14.6 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) FUN14 PF04930.10 ETO02285.1 - 5.8e-10 39.3 5.1 5.8e-10 39.3 3.5 1.7 2 0 0 2 2 2 1 FUN14 family CCAP PF11105.3 ETO02285.1 - 0.044 13.5 0.0 0.059 13.0 0.0 1.2 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a Copine PF07002.11 ETO02286.1 - 5.4e-14 52.1 1.2 7.3e-14 51.7 0.8 1.2 1 0 0 1 1 1 1 Copine Cons_hypoth698 PF03601.9 ETO02286.1 - 0.028 13.0 0.1 0.032 12.8 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 698 RVT_1 PF00078.22 ETO02287.1 - 3.8e-19 68.9 6.0 2.2e-18 66.4 2.8 2.6 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RST PF12174.3 ETO02287.1 - 0.034 13.9 6.0 0.084 12.6 0.1 3.8 4 1 1 5 5 5 0 RCD1-SRO-TAF4 (RST) plant domain PRF PF06875.6 ETO02287.1 - 0.062 12.5 0.2 0.14 11.3 0.1 1.6 1 0 0 1 1 1 0 Plethodontid receptivity factor PRF CMV_1a PF12467.3 ETO02290.1 - 0.077 13.3 8.8 0.038 14.3 3.2 2.0 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family MRP-L46 PF11788.3 ETO02290.1 - 0.097 13.3 5.7 0.046 14.3 2.4 1.6 2 0 0 2 2 2 0 39S mitochondrial ribosomal protein L46 DUF3987 PF13148.1 ETO02290.1 - 0.2 10.1 6.1 0.34 9.4 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF1104 PF06518.6 ETO02290.1 - 0.43 10.7 10.7 2.3 8.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) Vfa1 PF08432.5 ETO02290.1 - 1.7 8.6 11.8 1.3 9.0 5.5 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF3807 PF12720.2 ETO02291.1 - 0.039 14.1 7.3 0.056 13.5 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Sporozoite_P67 PF05642.6 ETO02291.1 - 0.12 10.2 10.0 0.13 10.0 7.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DDHD PF02862.12 ETO02291.1 - 0.24 11.1 6.6 0.33 10.6 4.6 1.3 1 0 0 1 1 1 0 DDHD domain DUF1510 PF07423.6 ETO02291.1 - 0.25 10.6 12.4 0.31 10.3 8.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) U79_P34 PF03064.11 ETO02291.1 - 0.52 9.7 9.5 0.68 9.4 6.6 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Neur_chan_memb PF02932.11 ETO02291.1 - 0.72 9.6 3.3 0.8 9.5 2.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2413 PF10310.4 ETO02291.1 - 1 8.1 16.2 1.2 7.8 11.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Cwf_Cwc_15 PF04889.7 ETO02291.1 - 1.2 8.7 16.6 1.6 8.4 11.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FLO_LFY PF01698.11 ETO02291.1 - 1.4 7.6 8.5 1.8 7.3 5.9 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein TATR PF03430.8 ETO02291.1 - 2.6 6.5 6.6 2.9 6.4 4.6 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Hid1 PF12722.2 ETO02291.1 - 3.1 5.3 6.6 3.2 5.3 4.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2201_N PF13203.1 ETO02291.1 - 3.1 6.8 8.0 3.4 6.7 5.5 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Paramyxo_ncap PF00973.14 ETO02291.1 - 3.8 6.0 6.3 4.6 5.8 4.4 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CDC45 PF02724.9 ETO02291.1 - 5.4 4.9 8.2 5.9 4.8 5.7 1.2 1 0 0 1 1 1 0 CDC45-like protein EBV-NA3 PF05009.7 ETO02291.1 - 6.1 6.0 6.7 9.3 5.4 4.7 1.4 1 1 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) RR_TM4-6 PF06459.7 ETO02291.1 - 9.3 6.0 9.6 11 5.7 6.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sec62 PF03839.11 ETO02294.1 - 0.00048 19.6 2.5 0.00058 19.3 1.7 1.1 1 0 0 1 1 1 1 Translocation protein Sec62 DUF2207 PF09972.4 ETO02294.1 - 0.027 13.0 0.6 0.03 12.9 0.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF948 PF06103.6 ETO02295.1 - 0.00098 18.9 6.0 0.0026 17.5 4.1 1.6 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF948) Reo_sigmaC PF04582.7 ETO02295.1 - 0.003 16.8 1.6 0.0031 16.7 1.1 1.0 1 0 0 1 1 1 1 Reovirus sigma C capsid protein DUF1204 PF06721.6 ETO02295.1 - 0.003 16.8 2.0 0.0034 16.6 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1204) CENP-Q PF13094.1 ETO02295.1 - 0.003 17.5 13.2 0.0037 17.2 9.1 1.1 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Herpes_UL6 PF01763.11 ETO02295.1 - 0.012 13.7 10.4 0.012 13.8 7.2 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like HALZ PF02183.13 ETO02295.1 - 0.019 14.6 7.0 5.7 6.7 4.8 2.4 1 1 0 1 1 1 0 Homeobox associated leucine zipper NYD-SP28_assoc PF14775.1 ETO02295.1 - 0.019 14.6 2.0 0.019 14.6 1.4 2.0 1 1 1 2 2 2 0 Sperm tail C-terminal domain DUF904 PF06005.7 ETO02295.1 - 0.021 15.1 12.2 0.036 14.3 8.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF904) BLOC1_2 PF10046.4 ETO02295.1 - 0.022 14.8 10.2 0.036 14.2 7.1 1.4 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.7 ETO02295.1 - 0.025 14.3 7.2 0.029 14.1 5.0 1.1 1 0 0 1 1 1 0 Laminin Domain II DUF1664 PF07889.7 ETO02295.1 - 0.035 13.8 4.9 0.049 13.4 3.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) UPF0242 PF06785.6 ETO02295.1 - 0.039 12.6 11.4 0.041 12.5 7.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Herpes_U30 PF04523.8 ETO02295.1 - 0.045 11.2 3.0 0.044 11.2 2.1 1.0 1 0 0 1 1 1 0 Herpes virus tegument protein U30 Mod_r PF07200.8 ETO02295.1 - 0.047 13.5 14.2 0.053 13.4 9.9 1.1 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein CENP-F_leu_zip PF10473.4 ETO02295.1 - 0.058 13.2 14.6 0.11 12.4 10.1 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_MT_bd PF06657.8 ETO02295.1 - 0.068 13.1 8.1 0.086 12.7 5.6 1.2 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Filament PF00038.16 ETO02295.1 - 0.084 12.3 13.0 0.097 12.1 9.0 1.1 1 0 0 1 1 1 0 Intermediate filament protein Dor1 PF04124.7 ETO02295.1 - 0.087 11.2 6.1 0.1 11.0 4.3 1.0 1 0 0 1 1 1 0 Dor1-like family IncA PF04156.9 ETO02295.1 - 0.089 12.3 13.4 0.094 12.3 9.3 1.1 1 0 0 1 1 1 0 IncA protein DUF1640 PF07798.6 ETO02295.1 - 0.094 12.7 8.9 0.06 13.3 4.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF2031 PF09592.5 ETO02295.1 - 0.11 11.6 14.0 0.11 11.6 9.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) Nup54 PF13874.1 ETO02295.1 - 0.12 12.0 9.3 0.31 10.6 6.5 1.6 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Transposase_22 PF02994.9 ETO02295.1 - 0.13 10.7 11.9 0.15 10.5 8.2 1.0 1 0 0 1 1 1 0 L1 transposable element DASH_Dad3 PF08656.5 ETO02295.1 - 0.13 11.9 6.9 3.8 7.2 4.8 2.1 1 1 0 1 1 1 0 DASH complex subunit Dad3 FlaC_arch PF05377.6 ETO02295.1 - 0.15 12.0 5.6 0.19 11.6 1.9 2.1 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) ADIP PF11559.3 ETO02295.1 - 0.16 11.8 14.7 0.18 11.7 10.2 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.9 ETO02295.1 - 0.18 11.4 14.9 0.21 11.2 10.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF724) EzrA PF06160.7 ETO02295.1 - 0.19 9.8 10.7 0.2 9.8 7.4 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA CorA PF01544.13 ETO02295.1 - 0.21 10.5 2.5 0.24 10.4 1.8 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Sec20 PF03908.8 ETO02295.1 - 0.23 11.1 4.8 0.37 10.5 3.3 1.4 1 1 0 1 1 1 0 Sec20 DivIVA PF05103.8 ETO02295.1 - 0.24 11.4 8.6 0.35 10.9 5.6 1.7 1 1 0 1 1 1 0 DivIVA protein GAS PF13851.1 ETO02295.1 - 0.24 10.5 19.3 0.26 10.4 13.4 1.0 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Imm46 PF15585.1 ETO02295.1 - 0.24 11.4 2.7 0.29 11.1 1.8 1.2 1 0 0 1 1 1 0 Immunity protein 46 Prominin PF05478.6 ETO02295.1 - 0.26 8.7 9.1 0.29 8.6 6.3 1.0 1 0 0 1 1 1 0 Prominin WXG100 PF06013.7 ETO02295.1 - 0.27 11.2 3.7 5.6 7.0 0.4 2.3 1 1 1 2 2 2 0 Proteins of 100 residues with WXG LPP PF04728.8 ETO02295.1 - 0.29 10.9 2.4 5 7.0 0.1 2.2 1 1 1 2 2 2 0 Lipoprotein leucine-zipper Neugrin PF06413.6 ETO02295.1 - 0.3 10.8 6.7 0.33 10.7 4.7 1.0 1 0 0 1 1 1 0 Neugrin UPF0118 PF01594.11 ETO02295.1 - 0.3 10.0 2.0 0.37 9.7 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF20 V-SNARE_C PF12352.3 ETO02295.1 - 0.3 11.1 2.6 5.4 7.1 0.0 2.1 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Golgin_A5 PF09787.4 ETO02295.1 - 0.3 9.5 11.3 0.31 9.5 7.8 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 Peptidase_M27 PF01742.12 ETO02295.1 - 0.31 9.8 6.3 0.34 9.6 4.3 1.1 1 0 0 1 1 1 0 Clostridial neurotoxin zinc protease DUF3450 PF11932.3 ETO02295.1 - 0.31 10.2 11.9 0.33 10.1 8.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Phage_GPO PF05929.6 ETO02295.1 - 0.34 10.1 9.9 0.35 10.0 6.8 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Med4 PF10018.4 ETO02295.1 - 0.43 9.9 6.9 0.56 9.5 4.7 1.4 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 TEX13 PF15186.1 ETO02295.1 - 0.43 10.1 4.6 0.49 9.9 3.2 1.1 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Mo25 PF08569.6 ETO02295.1 - 0.44 9.5 10.1 0.48 9.4 7.0 1.0 1 0 0 1 1 1 0 Mo25-like Wbp11 PF09429.5 ETO02295.1 - 0.45 10.5 14.2 0.58 10.1 9.8 1.2 1 0 0 1 1 1 0 WW domain binding protein 11 Cluap1 PF10234.4 ETO02295.1 - 0.47 9.6 9.5 0.55 9.3 6.6 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF4618 PF15397.1 ETO02295.1 - 0.49 9.6 14.4 0.62 9.3 10.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) bZIP_1 PF00170.16 ETO02295.1 - 0.5 10.3 18.5 2.3 8.2 0.5 2.6 1 1 1 2 2 2 0 bZIP transcription factor TBPIP PF07106.8 ETO02295.1 - 0.52 9.8 14.0 0.68 9.4 9.7 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CCDC92 PF14916.1 ETO02295.1 - 0.59 9.7 12.2 0.044 13.3 2.0 2.2 1 1 1 2 2 2 0 Coiled-coil domain of unknown function DUF4200 PF13863.1 ETO02295.1 - 0.59 10.0 14.3 0.86 9.5 9.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Tweety PF04906.8 ETO02295.1 - 0.62 8.4 4.3 0.71 8.2 3.0 1.0 1 0 0 1 1 1 0 Tweety Syntaxin-6_N PF09177.6 ETO02295.1 - 0.66 10.4 4.9 1.4 9.3 3.4 1.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal TMF_TATA_bd PF12325.3 ETO02295.1 - 0.67 9.6 11.5 0.88 9.3 8.0 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Atg14 PF10186.4 ETO02295.1 - 0.67 8.8 14.8 0.69 8.7 10.3 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 bZIP_2 PF07716.10 ETO02295.1 - 0.7 9.7 16.9 1.9 8.3 7.4 2.5 1 1 1 2 2 2 0 Basic region leucine zipper DUF972 PF06156.8 ETO02295.1 - 0.74 10.1 11.2 1.4 9.2 7.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Cas_Cmr5 PF09701.5 ETO02295.1 - 0.77 9.9 5.2 0.96 9.6 3.6 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr5) DUF1033 PF06279.6 ETO02295.1 - 0.8 9.5 5.9 0.93 9.3 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) DUF848 PF05852.6 ETO02295.1 - 0.83 9.4 9.9 1.1 9.1 6.9 1.2 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Seryl_tRNA_N PF02403.17 ETO02295.1 - 0.84 9.6 12.7 1.3 9.0 8.8 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain IFT57 PF10498.4 ETO02295.1 - 0.86 8.2 13.5 1 8.0 9.4 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Lzipper-MIP1 PF14389.1 ETO02295.1 - 0.91 9.6 10.5 1.5 8.9 1.5 2.2 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Spc7 PF08317.6 ETO02295.1 - 0.95 8.0 13.7 0.97 8.0 9.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Caudo_TAP PF02413.12 ETO02295.1 - 0.97 9.6 5.1 2.3 8.3 3.5 1.6 1 1 0 1 1 1 0 Caudovirales tail fibre assembly protein DUF745 PF05335.8 ETO02295.1 - 1 8.8 10.0 1.2 8.6 7.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF745) THOC7 PF05615.8 ETO02295.1 - 1 9.6 11.5 1.5 9.0 7.9 1.4 1 1 0 1 1 1 0 Tho complex subunit 7 SICA_beta PF12878.2 ETO02295.1 - 1 9.1 12.2 1.1 9.0 8.4 1.0 1 0 0 1 1 1 0 SICA extracellular beta domain APG6 PF04111.7 ETO02295.1 - 1.1 8.1 13.9 1.1 8.1 9.6 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 HAUS-augmin3 PF14932.1 ETO02295.1 - 1.3 8.1 16.1 1.3 8.1 11.2 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 XkdW PF09636.5 ETO02295.1 - 1.4 8.8 8.9 3 7.7 1.1 2.1 1 1 1 2 2 2 0 XkdW protein DUF651 PF04895.7 ETO02295.1 - 1.4 8.5 4.4 3.5 7.2 0.1 2.0 1 1 1 2 2 2 0 Archaeal protein of unknown function (DUF651) Glutaredoxin2_C PF04399.8 ETO02295.1 - 1.5 8.3 6.5 0.68 9.5 0.5 2.0 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain Phage_GP20 PF06810.6 ETO02295.1 - 1.7 8.0 15.9 2 7.8 11.0 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Ax_dynein_light PF10211.4 ETO02295.1 - 1.7 8.4 13.0 2.8 7.7 9.0 1.4 1 1 0 1 1 1 0 Axonemal dynein light chain Sec2p PF06428.6 ETO02295.1 - 1.8 8.4 13.9 58 3.6 9.6 2.0 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p YlqD PF11068.3 ETO02295.1 - 1.9 8.5 14.8 3.7 7.6 10.2 1.5 1 1 0 1 1 1 0 YlqD protein SecA_DEAD PF07517.9 ETO02295.1 - 1.9 7.7 7.6 2 7.6 5.3 1.1 1 0 0 1 1 1 0 SecA DEAD-like domain DUF2228 PF10228.4 ETO02295.1 - 1.9 7.9 7.1 2.2 7.7 4.7 1.3 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) Lebercilin PF15619.1 ETO02295.1 - 1.9 7.8 16.9 2.1 7.7 11.7 1.1 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease TMF_DNA_bd PF12329.3 ETO02295.1 - 2.2 8.1 17.1 0.9 9.3 8.5 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Mnd1 PF03962.10 ETO02295.1 - 2.2 7.9 13.7 2.8 7.5 9.5 1.2 1 0 0 1 1 1 0 Mnd1 family C_GCAxxG_C_C PF09719.5 ETO02295.1 - 2.5 7.9 6.5 2.9 7.7 4.5 1.1 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) DivIC PF04977.10 ETO02295.1 - 2.6 7.6 13.2 0.66 9.5 2.7 2.1 1 1 1 2 2 2 0 Septum formation initiator GrpE PF01025.14 ETO02295.1 - 2.6 7.5 8.0 4.4 6.8 5.5 1.4 1 1 0 1 1 1 0 GrpE TMCO5 PF14992.1 ETO02295.1 - 2.6 7.0 14.8 2.8 7.0 10.3 1.0 1 0 0 1 1 1 0 TMCO5 family CENP-H PF05837.7 ETO02295.1 - 3 8.0 12.3 4.2 7.6 8.5 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) HemX PF04375.9 ETO02295.1 - 3 6.3 9.7 3.1 6.3 6.7 1.0 1 0 0 1 1 1 0 HemX Apis_Csd PF11671.3 ETO02295.1 - 3.3 7.4 5.0 3.7 7.3 3.4 1.0 1 0 0 1 1 1 0 Complementary sex determiner protein MCC-bdg_PDZ PF10506.4 ETO02295.1 - 3.4 7.5 11.5 0.83 9.5 3.8 2.6 2 1 0 2 2 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome RNA_pol_Rpb1_5 PF04998.12 ETO02295.1 - 3.4 6.8 6.4 3.7 6.7 4.4 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF4471 PF14740.1 ETO02295.1 - 3.5 6.7 8.0 3.6 6.7 5.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) FliD_N PF02465.13 ETO02295.1 - 3.7 7.9 11.9 1.2 9.5 2.7 2.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Radical_SAM_N PF08497.5 ETO02295.1 - 3.9 6.3 5.6 3.8 6.3 3.9 1.0 1 0 0 1 1 1 0 Radical SAM N-terminal SlyX PF04102.7 ETO02295.1 - 4 7.8 9.2 1.9 8.9 1.8 2.1 1 1 1 2 2 2 0 SlyX DUF1754 PF08555.5 ETO02295.1 - 4.1 8.0 12.8 5.7 7.6 8.9 1.4 1 1 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) DUF4094 PF13334.1 ETO02295.1 - 4.5 7.7 8.9 2.8 8.4 2.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) SLX9 PF15341.1 ETO02295.1 - 5.3 7.4 11.3 6.5 7.2 7.8 1.1 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 DUF4298 PF14131.1 ETO02295.1 - 5.7 6.8 8.0 8.2 6.3 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) CENP-K PF11802.3 ETO02295.1 - 5.8 6.0 12.7 0.37 9.9 5.1 1.5 1 1 0 1 1 1 0 Centromere-associated protein K FCH PF00611.18 ETO02295.1 - 6 7.1 11.0 6.9 6.9 1.8 2.1 1 1 1 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain DUF2951 PF11166.3 ETO02295.1 - 6.3 6.7 10.2 1.9 8.4 2.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) Fzo_mitofusin PF04799.8 ETO02295.1 - 6.8 6.0 10.7 8.1 5.7 7.4 1.2 1 0 0 1 1 1 0 fzo-like conserved region UPF0449 PF15136.1 ETO02295.1 - 7.8 6.7 10.0 16 5.7 1.4 2.1 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 Erp_C PF06780.6 ETO02295.1 - 7.9 6.3 9.5 9.1 6.1 6.6 1.2 1 0 0 1 1 1 0 Erp protein C-terminus IKKbetaNEMObind PF12179.3 ETO02295.1 - 7.9 6.3 7.7 1.1 9.0 0.5 2.6 1 1 2 3 3 3 0 I-kappa-kinase-beta NEMO binding domain V_ATPase_I PF01496.14 ETO02295.1 - 8 4.1 11.4 8.1 4.1 7.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rho_Binding PF08912.6 ETO02295.1 - 8.6 6.7 17.7 0.087 13.1 5.5 2.0 1 1 1 2 2 1 0 Rho Binding Complex1_LYR PF05347.10 ETO02297.1 - 0.076 12.8 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Complex 1 protein (LYR family) CMAS PF02353.15 ETO02297.1 - 0.094 11.7 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase WD40 PF00400.27 ETO02298.1 - 8.5e-36 120.5 14.5 5e-11 42.0 0.4 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO02298.1 - 0.00026 20.7 1.9 0.068 12.8 0.2 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO02298.1 - 0.004 16.7 0.1 3.1 7.5 0.0 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat DUF3312 PF11768.3 ETO02298.1 - 0.0047 15.2 0.2 0.38 8.9 0.0 2.3 1 1 0 2 2 2 2 Protein of unknown function (DUF3312) Nucleoporin_N PF08801.6 ETO02298.1 - 0.014 14.1 9.6 1.6 7.3 3.9 3.1 2 2 0 2 2 2 0 Nup133 N terminal like Hce2 PF14856.1 ETO02298.1 - 0.11 12.4 2.8 0.15 11.9 0.2 2.2 2 0 0 2 2 2 0 Pathogen effector; putative necrosis-inducing factor zf-C3HC4_2 PF13923.1 ETO02299.1 - 0.042 13.8 3.1 0.4 10.7 1.3 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Bul1_C PF04426.7 ETO02300.1 - 0.007 15.5 2.0 0.0081 15.3 1.4 1.0 1 0 0 1 1 1 1 Bul1 C terminus Pinin_SDK_memA PF04696.8 ETO02300.1 - 0.017 14.7 4.5 0.019 14.5 3.1 1.1 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region RPOL_N PF14700.1 ETO02300.1 - 0.06 12.6 1.8 0.072 12.3 1.2 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal TRAP_alpha PF03896.11 ETO02300.1 - 0.065 12.2 1.8 0.064 12.2 1.3 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF329 PF03884.9 ETO02300.1 - 0.31 10.6 1.7 0.61 9.6 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF329) Vfa1 PF08432.5 ETO02300.1 - 0.58 10.1 7.9 0.7 9.8 5.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2457 PF10446.4 ETO02300.1 - 0.59 8.8 8.1 0.65 8.6 5.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) YqfQ PF14181.1 ETO02300.1 - 0.97 9.4 4.6 1.2 9.1 3.2 1.1 1 0 0 1 1 1 0 YqfQ-like protein U-box PF04564.10 ETO02302.1 - 3e-09 36.6 0.1 2.1e-08 33.9 0.0 2.5 2 0 0 2 2 2 1 U-box domain Kelch_1 PF01344.20 ETO02302.1 - 4.9e-07 29.1 7.0 1.5e-05 24.4 0.5 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO02302.1 - 2.5e-06 27.3 4.3 0.0044 17.1 0.2 4.5 3 1 1 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO02302.1 - 0.0025 17.9 0.0 0.17 12.1 0.0 3.2 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO02302.1 - 0.013 15.1 0.4 9.1 6.2 0.0 3.4 3 0 0 3 3 3 0 Kelch motif AAA_28 PF13521.1 ETO02302.1 - 0.31 10.9 5.4 8.4 6.3 0.8 3.0 2 1 0 2 2 2 0 AAA domain Kelch_1 PF01344.20 ETO02303.1 - 2.8e-06 26.7 0.9 1.3e-05 24.5 0.3 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETO02303.1 - 0.0001 22.2 0.2 0.00052 20.0 0.1 2.3 2 0 0 2 2 2 1 Kelch motif U-box PF04564.10 ETO02303.1 - 0.00085 19.2 0.5 0.00085 19.2 0.3 2.4 3 0 0 3 3 3 1 U-box domain Kelch_4 PF13418.1 ETO02303.1 - 0.044 13.5 0.3 1.7 8.4 0.0 2.6 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO02303.1 - 0.044 13.9 0.0 0.39 10.9 0.0 2.5 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO02303.1 - 0.073 13.0 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 Kelch motif DUF948 PF06103.6 ETO02303.1 - 5.2 6.9 18.6 3.9 7.4 0.2 3.9 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.4 ETO02305.1 - 0.098 12.8 14.2 1.9 8.6 1.5 3.2 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Lip_prot_lig_C PF10437.4 ETO02305.1 - 0.37 10.4 5.0 0.38 10.4 0.5 2.6 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus Cytadhesin_P30 PF07271.6 ETO02305.1 - 0.44 9.7 3.9 0.67 9.1 2.7 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 RPA_interact_M PF14767.1 ETO02306.1 - 0.036 14.8 0.2 0.064 14.0 0.1 1.4 1 0 0 1 1 1 0 Replication protein A interacting middle DUF2390 PF09523.5 ETO02306.1 - 0.1 12.7 1.3 0.24 11.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) HSBP1 PF06825.7 ETO02307.1 - 0.011 15.2 2.4 0.011 15.2 1.6 3.5 4 0 0 4 4 4 0 Heat shock factor binding protein 1 LXG PF04740.7 ETO02307.1 - 0.059 13.1 27.2 0.063 13.0 11.0 2.2 1 1 1 2 2 2 0 LXG domain of WXG superfamily OmpH PF03938.9 ETO02307.1 - 1 9.2 30.4 1.6 8.6 10.5 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) WD40 PF00400.27 ETO02308.1 - 1.1e-20 72.6 1.0 1.9e-10 40.2 0.1 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO02308.1 - 0.086 10.9 0.0 0.086 10.9 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 TUG-UBL1 PF11470.3 ETO02310.1 - 0.2 11.5 2.4 0.55 10.1 0.1 2.5 3 0 0 3 3 3 0 GLUT4 regulating protein TUG Tubulin PF00091.20 ETO02311.1 - 6.8e-24 84.8 0.2 1.4e-21 77.2 0.0 2.1 1 1 1 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.1 ETO02311.1 - 0.013 14.4 0.1 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Tubulin like Lipase_3 PF01764.20 ETO02311.1 - 0.023 14.3 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) WD40 PF00400.27 ETO02312.1 - 1.1e-05 25.1 2.6 2.9 7.9 0.0 5.2 4 2 0 4 4 4 3 WD domain, G-beta repeat DUF4564 PF15169.1 ETO02312.1 - 0.039 13.6 0.1 0.097 12.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4564) WD40 PF00400.27 ETO02315.1 - 5.9e-50 165.4 11.3 6.5e-12 44.8 0.1 5.5 5 1 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 ETO02315.1 - 1.2e-08 34.8 0.2 1.2e-05 25.0 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO02315.1 - 4.3e-07 28.4 1.2 0.011 13.9 0.1 3.7 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO02315.1 - 0.011 14.5 9.4 0.28 9.8 0.2 3.7 1 1 1 3 3 3 0 Nup133 N terminal like PD40 PF07676.7 ETO02315.1 - 3.9 7.2 6.4 5.7 6.7 0.0 3.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat EGF PF00008.22 ETO02316.1 - 3.8e-05 23.5 5.5 6.2e-05 22.8 3.8 1.3 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.2 ETO02316.1 - 0.0013 18.6 0.6 0.0029 17.5 0.4 1.6 1 0 0 1 1 1 1 Human growth factor-like EGF EGF_2 PF07974.8 ETO02316.1 - 0.0014 18.7 9.8 0.002 18.2 6.8 1.2 1 0 0 1 1 1 1 EGF-like domain CRPA PF05745.6 ETO02316.1 - 0.0048 16.6 0.1 0.007 16.1 0.1 1.2 1 0 0 1 1 1 1 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) TMEM154 PF15102.1 ETO02316.1 - 0.031 13.9 0.7 0.045 13.4 0.5 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF4448 PF14610.1 ETO02316.1 - 0.034 13.6 0.5 0.051 13.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) AMA-1 PF02430.10 ETO02316.1 - 0.043 12.7 1.5 0.051 12.4 1.0 1.1 1 0 0 1 1 1 0 Apical membrane antigen 1 SP_C-Propep PF08999.5 ETO02316.1 - 0.058 12.8 3.5 0.097 12.1 2.4 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Mid2 PF04478.7 ETO02316.1 - 0.24 10.8 3.8 0.1 11.9 1.1 1.5 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor DUF912 PF06024.7 ETO02316.1 - 0.49 10.4 4.0 0.2 11.7 0.5 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Laminin_EGF PF00053.19 ETO02316.1 - 1.2 9.1 9.5 2.1 8.3 6.6 1.3 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) Arch_flagellin PF01917.11 ETO02316.1 - 2.7 7.5 7.8 4.4 6.8 5.4 1.4 1 0 0 1 1 1 0 Archaebacterial flagellin WD40 PF00400.27 ETO02317.1 - 3.3e-05 23.5 1.5 0.016 15.1 0.4 2.7 2 1 0 2 2 2 2 WD domain, G-beta repeat GAGA_bind PF06217.7 ETO02318.1 - 0.3 11.0 6.0 0.35 10.8 4.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Peptidase_C14 PF00656.17 ETO02319.1 - 3.3e-05 23.7 0.1 3.6e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Caspase domain DUF3605 PF12239.3 ETO02319.1 - 0.064 13.1 0.5 0.11 12.3 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3605) DUF3421 PF11901.3 ETO02319.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3421) THOC7 PF05615.8 ETO02319.1 - 0.14 12.3 0.2 3.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Tho complex subunit 7 DUF1690 PF07956.6 ETO02320.1 - 0.071 13.0 11.1 0.1 12.5 7.7 1.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF2884 PF11101.3 ETO02320.1 - 0.1 11.9 3.1 0.081 12.2 1.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) Sec62 PF03839.11 ETO02320.1 - 0.14 11.4 6.8 0.17 11.2 4.7 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 YkyA PF10368.4 ETO02320.1 - 0.19 11.0 10.7 0.26 10.6 7.4 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF3810 PF12725.2 ETO02320.1 - 0.21 10.4 0.3 0.27 10.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) TMPIT PF07851.8 ETO02320.1 - 0.24 10.4 4.5 0.29 10.1 3.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein Holin_LLH PF09682.5 ETO02320.1 - 0.33 11.1 0.0 0.33 11.1 0.0 2.6 2 1 0 2 2 1 0 Phage holin protein (Holin_LLH) SPT16 PF08644.6 ETO02320.1 - 0.74 9.6 4.6 1 9.1 3.2 1.3 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) DUF883 PF05957.8 ETO02320.1 - 0.88 10.0 3.1 1 9.7 1.1 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Atg14 PF10186.4 ETO02320.1 - 2 7.3 7.7 2.4 7.0 5.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HSCB_C PF07743.8 ETO02320.1 - 2.1 8.8 6.6 2.6 8.5 1.9 2.3 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain Mt_ATP-synt_D PF05873.7 ETO02320.1 - 2.5 7.7 8.0 4.8 6.8 5.6 1.4 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DUF3584 PF12128.3 ETO02320.1 - 2.9 5.0 7.9 3.4 4.8 5.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3713 PF12506.3 ETO02320.1 - 3.6 7.6 9.0 6.6 6.8 6.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3713) DUF1664 PF07889.7 ETO02320.1 - 5.1 6.9 9.4 8.5 6.1 5.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FemAB PF02388.11 ETO02320.1 - 8.2 4.9 9.4 10 4.7 6.5 1.1 1 0 0 1 1 1 0 FemAB family RecO_C PF02565.10 ETO02321.1 - 2e-11 43.7 0.4 2.8e-11 43.2 0.3 1.1 1 0 0 1 1 1 1 Recombination protein O C terminal RecO_N PF11967.3 ETO02321.1 - 1.4e-06 28.0 0.0 2.3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Recombination protein O N terminal DUF3316 PF11777.3 ETO02322.1 - 0.031 14.0 0.0 0.071 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3316) RhoGEF PF00621.15 ETO02322.1 - 1.3 8.9 10.7 0.7 9.7 4.0 2.8 1 1 0 2 2 2 0 RhoGEF domain Cnd1 PF12717.2 ETO02324.1 - 2e-05 24.5 0.4 0.0041 16.9 0.1 2.1 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 CagY_M PF07337.6 ETO02324.1 - 0.0059 16.0 4.7 0.64 9.5 0.3 2.5 2 0 0 2 2 2 2 DC-EC Repeat DUF2789 PF10982.3 ETO02324.1 - 0.0092 15.9 0.7 2.7 8.0 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2789) Spore_III_AB PF09548.5 ETO02324.1 - 0.012 15.3 0.2 1 9.1 0.1 2.0 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) HEAT PF02985.17 ETO02324.1 - 0.017 15.1 0.0 8.8 6.7 0.0 2.6 2 0 0 2 2 2 0 HEAT repeat TSC22 PF01166.13 ETO02324.1 - 0.029 14.3 6.1 0.92 9.5 0.7 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF3283 PF11686.3 ETO02324.1 - 0.068 12.9 0.1 7.9 6.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3283) Gp-FAR-1 PF05823.7 ETO02324.1 - 0.23 11.3 1.3 13 5.7 0.1 2.1 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) CCDC-167 PF15188.1 ETO02324.1 - 0.24 11.3 2.3 7.5 6.5 0.1 2.5 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 TAN PF11640.3 ETO02324.1 - 0.29 10.8 2.2 10 5.8 0.1 3.1 1 1 1 2 2 2 0 Telomere-length maintenance and DNA damage repair CAAP1 PF15335.1 ETO02324.1 - 1.5 9.1 4.2 25 5.1 0.2 2.6 2 1 1 3 3 3 0 Caspase activity and apoptosis inhibitor 1 tRNA-synt_1g PF09334.6 ETO02325.1 - 6.9e-05 21.6 1.0 0.00024 19.8 0.7 1.8 1 1 1 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 ETO02325.1 - 0.00017 19.7 0.0 0.00017 19.7 0.0 2.2 1 1 2 3 3 3 1 tRNA synthetases class I (I, L, M and V) RNase_H2-Ydr279 PF09468.5 ETO02325.1 - 0.059 12.5 3.4 0.065 12.4 2.4 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) HSP90 PF00183.13 ETO02325.1 - 0.086 11.2 5.9 0.097 11.0 4.1 1.1 1 0 0 1 1 1 0 Hsp90 protein RNA_pol_Rpc4 PF05132.9 ETO02325.1 - 1.2 9.0 7.2 1.6 8.6 5.0 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 YqfQ PF14181.1 ETO02325.1 - 2.7 8.0 8.1 3.6 7.5 5.6 1.1 1 0 0 1 1 1 0 YqfQ-like protein Val_tRNA-synt_C PF10458.4 ETO02326.1 - 0.0081 16.2 0.9 0.0081 16.2 0.6 2.3 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm Anthrax_toxA PF03497.11 ETO02326.1 - 0.12 12.1 1.9 0.13 12.0 1.3 1.1 1 0 0 1 1 1 0 Anthrax toxin LF subunit Methyltransf_25 PF13649.1 ETO02327.1 - 0.021 15.1 0.0 0.031 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF2939 PF11159.3 ETO02328.1 - 0.0011 19.1 0.4 0.94 9.6 0.2 3.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2939) Trigger_C PF05698.9 ETO02328.1 - 0.0042 16.9 15.1 0.53 10.1 4.5 3.5 1 1 2 3 3 3 2 Bacterial trigger factor protein (TF) C-terminus DUF445 PF04286.7 ETO02328.1 - 0.019 14.5 9.6 0.025 14.1 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) HI0933_like PF03486.9 ETO02328.1 - 0.035 12.5 1.9 0.4 9.0 0.8 1.9 1 1 1 2 2 2 0 HI0933-like protein DUF668 PF05003.7 ETO02328.1 - 0.067 13.4 4.9 1.4 9.2 0.8 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF668) DUF2861 PF11060.3 ETO02328.1 - 0.074 12.3 2.6 4 6.6 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2861) DUF2267 PF10025.4 ETO02328.1 - 0.16 12.0 10.4 5.6 7.0 0.0 3.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2267) Ribosomal_L12 PF00542.14 ETO02328.1 - 0.19 11.7 11.0 8.1 6.5 0.9 3.9 1 1 3 4 4 4 0 Ribosomal protein L7/L12 C-terminal domain DUF1525 PF07511.6 ETO02328.1 - 0.4 10.6 5.5 30 4.6 0.3 3.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1525) Peptidase_S48 PF03574.10 ETO02328.1 - 0.65 9.9 7.2 40 4.1 0.2 3.2 1 1 1 2 2 2 0 Peptidase family S48 WASH-7_mid PF14744.1 ETO02328.1 - 1.3 7.7 3.8 12 4.6 0.6 2.0 1 1 1 2 2 2 0 WASH complex subunit 7 7TMR-HDED PF07697.6 ETO02328.1 - 1.4 8.5 11.7 1.9 8.1 8.1 1.2 1 0 0 1 1 1 0 7TM-HD extracellular YtxH PF12732.2 ETO02328.1 - 2.8 8.3 15.3 3.7e+03 -1.7 10.6 3.1 1 1 0 1 1 1 0 YtxH-like protein OTU PF02338.14 ETO02328.1 - 7.6 7.1 8.8 7.3e+02 0.7 6.1 2.9 1 1 0 1 1 1 0 OTU-like cysteine protease NapE PF06796.6 ETO02329.1 - 0.036 13.3 0.3 0.67 9.3 0.0 2.3 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE Sigma_reg_N PF13800.1 ETO02329.1 - 4.9 7.2 7.0 1.1 9.3 2.5 1.7 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Nop14 PF04147.7 ETO02330.1 - 0.088 10.7 48.1 0.1 10.5 33.4 1.0 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 ETO02330.1 - 0.18 11.1 44.8 0.21 10.9 31.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SDA1 PF05285.7 ETO02330.1 - 0.21 10.8 43.3 0.24 10.6 30.0 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 ETO02330.1 - 0.23 9.4 31.8 0.23 9.4 22.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.7 ETO02330.1 - 0.26 9.5 48.5 0.31 9.3 33.6 1.0 1 0 0 1 1 1 0 Mpp10 protein Spore_coat_CotO PF14153.1 ETO02330.1 - 0.26 10.6 37.8 0.31 10.4 26.2 1.1 1 0 0 1 1 1 0 Spore coat protein CotO CENP-T PF15511.1 ETO02330.1 - 0.33 10.1 27.9 0.36 10.0 19.3 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T SAPS PF04499.10 ETO02330.1 - 2.3 6.7 26.6 2.6 6.5 18.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Raftlin PF15250.1 ETO02330.1 - 2.6 6.4 19.7 3 6.2 13.7 1.0 1 0 0 1 1 1 0 Raftlin Vfa1 PF08432.5 ETO02330.1 - 3 7.8 34.1 4.7 7.1 23.6 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Drc1-Sld2 PF11719.3 ETO02330.1 - 3.5 6.6 29.6 4.6 6.2 20.5 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein CKAP2_C PF15297.1 ETO02330.1 - 3.6 6.2 28.4 4.5 5.9 19.7 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus SprA-related PF12118.3 ETO02330.1 - 4.9 6.3 29.8 5.6 6.2 20.6 1.2 1 0 0 1 1 1 0 SprA-related family DUF4045 PF13254.1 ETO02330.1 - 6.7 5.8 26.5 7 5.8 18.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DDRGK PF09756.4 ETO02330.1 - 7 6.0 39.1 10 5.5 27.1 1.4 1 0 0 1 1 1 0 DDRGK domain CAP_GLY PF01302.20 ETO02331.1 - 0.012 15.3 0.3 0.029 14.0 0.2 1.7 1 1 0 1 1 1 0 CAP-Gly domain Med15 PF09606.5 ETO02334.1 - 0.0049 15.1 10.6 0.0037 15.5 7.3 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal FimP PF09766.4 ETO02334.1 - 0.015 14.3 8.7 0.013 14.5 6.0 1.1 1 0 0 1 1 1 0 Fms-interacting protein DUF4647 PF15504.1 ETO02334.1 - 0.061 12.1 3.7 0.057 12.2 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) BAF1_ABF1 PF04684.8 ETO02334.1 - 0.24 10.2 19.5 0.28 10.0 13.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF1635 PF07795.6 ETO02334.1 - 1.4 8.2 7.7 2.2 7.5 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF4175 PF13779.1 ETO02334.1 - 2.5 5.6 15.6 2.6 5.6 10.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Activator_LAG-3 PF11498.3 ETO02334.1 - 3 6.5 21.6 4.4 5.9 15.0 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Apc15p PF05841.6 ETO02334.1 - 4.4 8.0 15.2 0.38 11.5 7.3 1.5 2 0 0 2 2 2 0 Apc15p protein DivIC PF04977.10 ETO02334.1 - 8.9 5.8 10.7 16 5.0 7.4 1.4 1 0 0 1 1 1 0 Septum formation initiator PHD_3 PF13922.1 ETO02334.1 - 8.9 6.6 13.8 2.2 8.5 7.6 1.6 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx TPR_12 PF13424.1 ETO02335.1 - 1.3e-10 41.0 0.5 1.8e-09 37.3 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO02335.1 - 7.6e-10 37.8 4.5 2.2e-07 30.1 1.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO02335.1 - 1.1e-09 37.7 3.5 3.1e-08 33.1 0.1 3.1 2 1 1 3 3 3 1 TPR repeat TPR_1 PF00515.23 ETO02335.1 - 2.8e-08 33.0 1.6 1.1e-07 31.1 1.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO02335.1 - 3.9e-07 29.5 3.1 7.4e-06 25.4 0.4 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETO02335.1 - 5.7e-07 29.2 0.0 2.1e-05 24.2 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO02335.1 - 2.1e-05 23.9 0.3 0.00015 21.2 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_3 PF07720.7 ETO02335.1 - 8.3e-05 22.2 3.0 0.00024 20.8 2.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat eIF3g PF12353.3 ETO02335.1 - 0.0035 17.2 1.0 0.0081 16.0 0.7 1.7 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G TPR_6 PF13174.1 ETO02335.1 - 0.0089 16.4 1.0 0.046 14.1 0.2 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO02335.1 - 0.028 15.1 0.1 0.26 11.9 0.0 2.3 2 1 0 2 2 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETO02335.1 - 0.096 13.3 0.0 6.2 7.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat MMR_HSR1 PF01926.18 ETO02336.1 - 0.0029 17.5 0.0 0.0052 16.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase UPF0081 PF03652.10 ETO02336.1 - 0.12 12.5 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0081) ETRAMP PF09716.5 ETO02336.1 - 1 9.3 4.6 2.8 7.9 3.2 1.8 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) NACHT PF05729.7 ETO02337.1 - 7.8e-11 41.9 0.0 1.7e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO02337.1 - 1.4e-06 28.6 0.2 1.4e-06 28.6 0.1 3.0 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 ETO02337.1 - 2.5e-06 27.6 0.1 1.8e-05 24.9 0.0 2.4 3 0 0 3 3 2 1 AAA domain UPF0079 PF02367.12 ETO02337.1 - 0.00041 19.9 0.1 0.0041 16.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 ETO02337.1 - 0.00046 20.9 1.9 0.0045 17.8 0.0 3.0 3 1 0 3 3 3 1 AAA domain KAP_NTPase PF07693.9 ETO02337.1 - 0.013 14.4 0.8 0.3 10.0 0.0 2.5 1 1 1 2 2 2 0 KAP family P-loop domain ABC_tran PF00005.22 ETO02337.1 - 0.015 15.5 0.9 0.04 14.1 0.0 2.2 2 1 0 2 2 2 0 ABC transporter PRK PF00485.13 ETO02337.1 - 0.016 14.7 0.0 0.05 13.1 0.0 1.9 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.17 ETO02337.1 - 0.016 15.3 1.9 0.038 14.1 0.0 2.4 2 1 0 2 2 2 0 RNA helicase DUF258 PF03193.11 ETO02337.1 - 0.016 14.3 0.0 0.17 11.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 ETO02337.1 - 0.027 13.5 0.0 0.077 12.0 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.24 ETO02337.1 - 0.032 14.4 0.0 0.08 13.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP_bind_2 PF03668.10 ETO02337.1 - 0.059 12.4 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop ATPase protein family AAA_16 PF13191.1 ETO02337.1 - 0.071 13.0 0.4 0.79 9.6 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 ETO02337.1 - 0.073 12.9 0.5 0.23 11.3 0.0 2.2 3 1 0 3 3 3 0 AAA domain AAA_5 PF07728.9 ETO02337.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) YcbB PF08664.5 ETO02337.1 - 0.37 10.5 0.0 0.37 10.5 0.0 2.9 3 1 1 4 4 4 0 YcbB domain PRP1_N PF06424.7 ETO02337.1 - 0.66 10.2 7.7 0.11 12.8 2.1 2.1 2 0 0 2 2 1 0 PRP1 splicing factor, N-terminal DUF2779 PF11074.3 ETO02337.1 - 0.97 9.4 8.0 0.52 10.3 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function(DUF2779) TPR_12 PF13424.1 ETO02338.1 - 2.2e-30 104.4 2.9 1.5e-18 66.5 0.3 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO02338.1 - 4.5e-12 44.8 0.4 8.7e-07 28.2 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO02338.1 - 2.8e-11 42.9 0.0 0.0007 19.4 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO02338.1 - 6.9e-11 41.6 15.4 1.8e-08 33.9 3.2 2.0 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETO02338.1 - 7.8e-11 41.1 11.6 3.6e-07 29.5 0.3 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO02338.1 - 4.4e-10 38.6 4.3 0.00023 20.8 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO02338.1 - 1.6e-09 36.8 11.3 2.5e-05 23.7 1.5 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO02338.1 - 9.3e-06 25.4 5.2 0.24 11.7 0.5 3.8 3 2 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO02338.1 - 0.081 13.0 1.9 0.11 12.6 1.3 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Mob_Pre PF01076.14 ETO02338.1 - 0.13 11.9 0.9 0.18 11.4 0.6 1.1 1 0 0 1 1 1 0 Plasmid recombination enzyme AAA_12 PF13087.1 ETO02338.1 - 0.22 10.8 2.0 3.4 6.9 0.1 2.0 1 1 1 2 2 2 0 AAA domain LRR_4 PF12799.2 ETO02339.1 - 6e-07 28.9 16.7 0.0066 16.0 2.6 3.5 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO02339.1 - 1.2e-06 28.2 9.6 0.00027 20.6 3.1 3.0 2 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 ETO02339.1 - 1.6e-06 27.3 11.7 0.53 10.5 0.1 5.8 6 0 0 6 6 6 3 Leucine Rich Repeat TRCF PF03461.10 ETO02339.1 - 0.0092 15.9 1.1 0.88 9.5 0.1 3.0 2 1 1 3 3 3 1 TRCF domain LRR_6 PF13516.1 ETO02339.1 - 0.14 12.3 11.7 26 5.2 0.0 5.0 5 0 0 5 5 5 0 Leucine Rich repeat LRR_7 PF13504.1 ETO02339.1 - 0.16 12.2 13.1 20 5.9 0.2 4.7 4 0 0 4 4 4 0 Leucine rich repeat SpoVIF PF14069.1 ETO02340.1 - 0.0075 15.9 0.3 0.48 10.1 0.0 2.4 1 1 1 2 2 2 1 Stage VI sporulation protein F GvpL_GvpF PF06386.6 ETO02340.1 - 0.076 12.5 2.1 0.09 12.3 1.5 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Colicin-DNase PF12639.2 ETO02340.1 - 0.25 11.5 2.5 0.39 10.9 1.7 1.3 1 0 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin Occludin_ELL PF07303.8 ETO02340.1 - 0.71 10.6 7.7 0.53 11.0 3.9 1.7 1 1 0 1 1 1 0 Occludin homology domain DUF2499 PF10693.4 ETO02341.1 - 0.63 10.1 6.8 0.28 11.2 0.3 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF2499) Lactamase_B PF00753.22 ETO02342.1 - 2.2e-23 82.9 0.2 3e-23 82.4 0.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETO02342.1 - 3.4e-09 36.5 0.3 5.5e-09 35.8 0.2 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain UN_NPL4 PF11543.3 ETO02342.1 - 0.076 13.2 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 DUF3895 PF13034.1 ETO02342.1 - 0.39 10.2 4.0 0.62 9.5 1.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3895) Myosin_head PF00063.16 ETO02343.1 - 9.9e-112 374.2 6.8 5.8e-77 259.3 0.7 2.0 2 0 0 2 2 2 2 Myosin head (motor domain) zf-TRAF PF02176.13 ETO02346.1 - 2.6e-06 27.6 0.9 2.6e-06 27.6 0.6 2.9 2 1 0 2 2 2 1 TRAF-type zinc finger EMP24_GP25L PF01105.19 ETO02346.1 - 0.0021 17.7 0.7 0.0041 16.8 0.5 1.5 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DivIC PF04977.10 ETO02346.1 - 0.0031 16.9 5.5 0.011 15.2 3.8 1.9 1 0 0 1 1 1 1 Septum formation initiator DUF904 PF06005.7 ETO02346.1 - 0.0043 17.3 5.9 0.0043 17.3 4.1 2.6 4 1 0 4 4 3 1 Protein of unknown function (DUF904) DUF972 PF06156.8 ETO02346.1 - 0.0062 16.8 6.2 0.025 14.9 4.3 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF972) Herpes_BLRF2 PF05812.7 ETO02346.1 - 0.0065 16.2 1.9 0.0065 16.2 1.3 2.2 2 0 0 2 2 2 1 Herpesvirus BLRF2 protein CENP-F_leu_zip PF10473.4 ETO02346.1 - 0.013 15.3 7.6 0.013 15.3 5.2 2.4 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.4 ETO02346.1 - 0.014 14.4 8.7 0.024 13.6 6.0 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TSC22 PF01166.13 ETO02346.1 - 0.019 14.9 2.3 0.019 14.9 1.6 2.3 2 0 0 2 2 1 0 TSC-22/dip/bun family bZIP_1 PF00170.16 ETO02346.1 - 0.021 14.7 4.3 0.021 14.7 3.0 2.1 2 0 0 2 2 1 0 bZIP transcription factor DUF3450 PF11932.3 ETO02346.1 - 0.057 12.6 3.2 0.1 11.8 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) zf-H2C2_5 PF13909.1 ETO02346.1 - 0.061 13.5 4.3 0.89 9.9 0.1 3.5 3 0 0 3 3 2 0 C2H2-type zinc-finger domain Pol_alpha_B_N PF08418.5 ETO02346.1 - 0.082 12.4 1.4 0.14 11.6 0.9 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Mto2_bdg PF12808.2 ETO02346.1 - 0.19 11.8 2.4 0.71 10.0 1.7 2.0 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF2681 PF10883.3 ETO02346.1 - 0.22 11.7 8.4 0.24 11.6 4.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) Seryl_tRNA_N PF02403.17 ETO02346.1 - 0.27 11.2 7.0 0.2 11.6 2.8 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain zf-BED PF02892.10 ETO02346.1 - 0.32 10.7 2.8 7.6 6.3 0.1 3.3 3 0 0 3 3 3 0 BED zinc finger DUF724 PF05266.9 ETO02346.1 - 0.57 9.7 7.5 0.36 10.4 3.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Lipoxygenase PF00305.14 ETO02347.1 - 0.018 13.0 1.0 0.025 12.6 0.7 1.1 1 0 0 1 1 1 0 Lipoxygenase TMEM138 PF14935.1 ETO02347.1 - 0.02 15.2 0.6 0.13 12.6 0.1 2.1 1 1 1 2 2 2 0 Transmembrane protein 138 ENTH PF01417.15 ETO02347.1 - 0.083 12.7 0.5 0.22 11.4 0.4 1.8 1 1 0 1 1 1 0 ENTH domain Amb_V_allergen PF03913.8 ETO02347.1 - 0.086 12.5 0.7 0.16 11.6 0.5 1.4 1 0 0 1 1 1 0 Amb V Allergen Maelstrom PF13017.1 ETO02348.1 - 0.46 9.9 4.8 0.46 9.9 2.5 1.7 1 1 1 2 2 2 0 piRNA pathway germ-plasm component Kelch_4 PF13418.1 ETO02350.1 - 0.0018 17.9 0.3 0.01 15.5 0.1 2.0 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO02350.1 - 0.028 14.6 0.0 0.055 13.6 0.0 1.5 1 0 0 1 1 1 0 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO02350.1 - 0.032 14.3 0.5 0.11 12.6 0.3 2.0 2 0 0 2 2 2 0 Kelch motif DUF3126 PF11324.3 ETO02350.1 - 0.048 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3126) Kelch_1 PF01344.20 ETO02350.1 - 0.079 12.5 0.3 0.079 12.5 0.2 2.0 2 0 0 2 2 2 0 Kelch motif DUF3206 PF11472.3 ETO02350.1 - 0.1 12.3 0.2 0.32 10.7 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3206) DUF4378 PF14309.1 ETO02350.1 - 0.14 12.2 1.5 0.24 11.4 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) RPEL PF02755.10 ETO02351.1 - 0.00018 20.7 76.3 0.23 10.8 1.1 15.9 18 0 0 18 18 18 10 RPEL repeat tRNA-synt_1c PF00749.16 ETO02354.1 - 0.022 13.4 0.2 0.024 13.3 0.1 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain Phage_tail_2 PF06199.6 ETO02354.1 - 0.063 13.3 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Phage major tail protein 2 Phasin_2 PF09361.5 ETO02355.1 - 0.036 14.0 0.9 0.42 10.6 0.1 2.5 2 1 0 2 2 2 0 Phasin protein L31 PF09784.4 ETO02355.1 - 0.04 13.9 1.4 0.056 13.5 0.5 1.7 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L31 HDAC4_Gln PF12203.3 ETO02355.1 - 0.96 9.4 12.7 1.6 8.6 3.5 2.5 2 1 0 2 2 2 0 Glutamine rich N terminal domain of histone deacetylase 4 RPA_interact_M PF14767.1 ETO02355.1 - 2.7 8.8 8.9 3.3 8.5 2.8 2.6 1 1 2 3 3 3 0 Replication protein A interacting middle DUF4473 PF14747.1 ETO02355.1 - 5 7.4 11.6 0.47 10.6 1.8 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4473) CBP4 PF07960.6 ETO02355.1 - 7.3 6.2 8.7 4.5 6.8 4.4 1.8 1 1 1 2 2 2 0 CBP4 Pkinase PF00069.20 ETO02357.1 - 3.2e-08 33.0 0.0 3.5e-08 32.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO02357.1 - 0.00044 19.4 0.0 0.00052 19.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase NLE PF08154.7 ETO02358.1 - 0.06 13.3 0.9 0.66 10.0 0.0 2.7 3 1 1 4 4 4 0 NLE (NUC135) domain Helicase_Sgs1 PF11408.3 ETO02358.1 - 0.085 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Sgs1 RecQ helicase PAX PF00292.13 ETO02359.1 - 0.084 12.5 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 'Paired box' domain Sarcolipin PF05366.6 ETO02359.1 - 0.53 9.7 3.1 1.4 8.4 0.3 2.4 2 0 0 2 2 2 0 Sarcolipin Kelch_1 PF01344.20 ETO02360.1 - 1.1e-08 34.4 2.9 0.00019 20.9 0.4 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 ETO02360.1 - 2.7e-08 33.4 0.0 0.0052 16.5 0.0 2.4 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO02360.1 - 2e-07 30.7 0.4 0.011 15.6 0.0 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.1 ETO02360.1 - 1.6e-06 27.9 1.6 0.0035 17.4 0.3 2.5 1 1 1 2 2 2 2 Kelch motif Kelch_2 PF07646.10 ETO02360.1 - 1.7e-06 27.5 0.4 0.00094 18.8 0.2 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 ETO02360.1 - 3.1e-06 27.1 0.1 0.0043 17.1 0.0 2.9 3 0 0 3 3 3 2 Galactose oxidase, central domain tRNA_Me_trans PF03054.11 ETO02360.1 - 0.072 11.6 0.0 0.097 11.2 0.0 1.1 1 0 0 1 1 1 0 tRNA methyl transferase HECT PF00632.20 ETO02361.1 - 1.3e-16 60.6 0.0 1.4e-16 60.5 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) TLD PF07534.11 ETO02362.1 - 0.054 13.4 0.5 0.9 9.5 0.0 2.7 2 1 0 2 2 2 0 TLD Med29 PF11568.3 ETO02364.1 - 0.0094 16.0 6.8 0.017 15.1 4.7 1.4 1 0 0 1 1 1 1 Mediator complex subunit 29 Tropomyosin_1 PF12718.2 ETO02364.1 - 0.014 15.2 3.1 0.014 15.2 2.2 2.4 1 1 1 2 2 2 0 Tropomyosin like Tup_N PF08581.5 ETO02364.1 - 0.69 10.1 6.2 7.6 6.8 0.6 2.7 2 0 0 2 2 2 0 Tup N-terminal Prefoldin PF02996.12 ETO02364.1 - 1.5 8.4 6.9 7.1 6.3 1.4 2.3 2 0 0 2 2 2 0 Prefoldin subunit DivIVA PF05103.8 ETO02364.1 - 2.2 8.3 11.4 0.54 10.3 1.7 3.1 1 1 1 2 2 2 0 DivIVA protein Mu-like_Pro PF10123.4 ETO02365.1 - 0.091 12.1 2.3 0.13 11.7 1.6 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein PRP1_N PF06424.7 ETO02365.1 - 0.38 11.0 4.8 12 6.2 1.1 2.3 2 1 0 2 2 2 0 PRP1 splicing factor, N-terminal DUF2951 PF11166.3 ETO02365.1 - 2.4 8.0 4.9 0.35 10.7 0.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2951) Tcf25 PF04910.9 ETO02366.1 - 9.6e-60 202.4 3.1 9.6e-60 202.4 2.2 2.8 3 1 0 3 3 3 1 Transcriptional repressor TCF25 DUF2431 PF10354.4 ETO02367.1 - 0.027 14.4 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) Mto2_bdg PF12808.2 ETO02368.1 - 0.012 15.6 4.1 0.012 15.6 2.8 1.7 2 0 0 2 2 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Spc7_N PF15402.1 ETO02368.1 - 0.042 11.8 4.9 0.045 11.7 3.4 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 GrpE PF01025.14 ETO02368.1 - 0.06 12.8 7.7 0.063 12.8 5.3 1.1 1 0 0 1 1 1 0 GrpE DUF1474 PF07342.6 ETO02368.1 - 0.079 13.1 3.9 0.096 12.9 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1474) DUF3316 PF11777.3 ETO02368.1 - 0.11 12.2 0.8 0.12 12.1 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3316) Lipoprotein_20 PF13942.1 ETO02368.1 - 0.13 11.7 5.7 0.15 11.6 4.0 1.2 1 0 0 1 1 1 0 YfhG lipoprotein PUB PF09409.5 ETO02368.1 - 0.21 11.3 8.6 0.78 9.5 3.1 2.1 1 1 1 2 2 2 0 PUB domain DUF2400 PF09674.5 ETO02368.1 - 0.44 10.2 3.4 0.48 10.0 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF2570 PF10828.3 ETO02368.1 - 0.47 10.0 6.9 0.71 9.5 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Peptidase_C6 PF00851.13 ETO02368.1 - 0.52 8.8 6.4 0.55 8.7 4.5 1.0 1 0 0 1 1 1 0 Helper component proteinase TcdB_N PF12918.2 ETO02368.1 - 0.6 10.2 12.7 0.51 10.4 4.8 2.4 1 1 1 2 2 2 0 TcdB toxin N-terminal helical domain Hom_end_hint PF05203.11 ETO02368.1 - 0.66 9.6 2.9 0.75 9.4 2.0 1.0 1 0 0 1 1 1 0 Hom_end-associated Hint Borrelia_orfA PF02414.10 ETO02368.1 - 0.67 9.0 18.8 0.74 8.8 13.0 1.0 1 0 0 1 1 1 0 Borrelia ORF-A Colicin-DNase PF12639.2 ETO02368.1 - 0.69 10.1 3.4 0.83 9.9 2.3 1.1 1 0 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin Atg14 PF10186.4 ETO02368.1 - 0.73 8.7 9.1 0.79 8.6 6.3 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Orbi_VP5 PF00901.12 ETO02368.1 - 0.81 7.8 6.9 0.91 7.6 4.8 1.0 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 ARD PF03079.9 ETO02368.1 - 1 9.3 5.6 1.2 9.0 3.9 1.1 1 0 0 1 1 1 0 ARD/ARD' family DivIC PF04977.10 ETO02368.1 - 1.1 8.7 7.9 1.6 8.2 5.5 1.4 1 0 0 1 1 1 0 Septum formation initiator IncA PF04156.9 ETO02368.1 - 1.7 8.1 9.4 2.1 7.9 6.5 1.2 1 0 0 1 1 1 0 IncA protein DUF3373 PF11853.3 ETO02368.1 - 2.1 6.7 6.5 2.2 6.7 4.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF334 PF03904.8 ETO02368.1 - 2.2 7.5 9.1 2.7 7.2 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF334) TMPIT PF07851.8 ETO02368.1 - 2.5 7.0 7.8 2.7 6.9 5.4 1.0 1 0 0 1 1 1 0 TMPIT-like protein WD40 PF00400.27 ETO02370.1 - 1.8e-91 297.0 20.0 2e-14 52.8 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO02370.1 - 1.6e-17 63.8 0.0 8.7e-06 25.5 0.0 3.4 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 ETO02370.1 - 1.5e-08 34.3 1.8 0.0018 17.7 0.7 3.8 1 1 0 1 1 1 1 PQQ-like domain Nup160 PF11715.3 ETO02370.1 - 2e-08 32.8 2.2 0.027 12.6 0.1 4.6 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Gmad1 PF10647.4 ETO02370.1 - 8.5e-08 31.8 0.2 0.0059 16.0 0.1 3.9 2 2 1 3 3 3 2 Lipoprotein LpqB beta-propeller domain Proteasome_A_N PF10584.4 ETO02370.1 - 6.7e-06 25.3 8.9 7.6 5.9 0.0 6.7 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature DUF727 PF05303.7 ETO02370.1 - 3.2e-05 23.6 0.2 8.8 6.1 0.0 5.7 1 1 5 6 6 6 0 Protein of unknown function (DUF727) PD40 PF07676.7 ETO02370.1 - 4.1e-05 23.1 10.0 14 5.4 0.0 6.5 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO02370.1 - 6.5e-05 21.3 0.5 0.17 10.1 0.0 3.0 1 1 2 3 3 3 2 Cytochrome D1 heme domain BBS2_Mid PF14783.1 ETO02370.1 - 0.00016 21.4 1.6 3.7 7.3 0.1 5.1 1 1 4 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Rpn3_C PF08375.6 ETO02370.1 - 0.00032 21.0 0.0 1.6 9.1 0.0 4.3 5 0 0 5 5 5 1 Proteasome regulatory subunit C-terminal Nucleoporin_N PF08801.6 ETO02370.1 - 0.00034 19.4 12.8 0.61 8.7 2.5 4.2 1 1 3 4 4 4 2 Nup133 N terminal like DUF3732 PF12532.3 ETO02370.1 - 0.00076 19.0 1.0 21 4.5 0.0 4.8 2 2 3 5 5 5 0 Protein of unknown function (DUF3732) BLUF PF04940.7 ETO02370.1 - 0.00099 18.7 0.0 35 4.2 0.0 4.9 5 0 0 5 5 5 0 Sensors of blue-light using FAD Nbas_N PF15492.1 ETO02370.1 - 0.0022 17.1 3.2 1 8.3 0.2 3.7 1 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Pentapeptide_3 PF13576.1 ETO02370.1 - 0.0023 17.7 2.7 0.0074 16.1 1.9 2.0 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) DPPIV_N PF00930.16 ETO02370.1 - 0.0071 14.9 0.3 36 2.7 0.0 4.3 2 2 3 5 5 5 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Pentapeptide_4 PF13599.1 ETO02370.1 - 0.0079 15.9 0.8 0.015 15.0 0.6 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) DUF1258 PF06869.7 ETO02370.1 - 0.0096 15.0 0.5 5.3 6.0 0.0 3.7 1 1 2 4 4 4 1 Protein of unknown function (DUF1258) TolB_N PF04052.8 ETO02370.1 - 0.012 15.6 0.0 1.3e+02 2.6 0.0 5.4 7 0 0 7 7 6 0 TolB amino-terminal domain IKI3 PF04762.7 ETO02370.1 - 0.024 12.4 0.5 2 6.0 0.0 2.2 1 1 0 2 2 2 0 IKI3 family Pentapeptide PF00805.17 ETO02370.1 - 0.027 13.7 1.8 0.25 10.6 1.2 2.1 1 1 1 2 2 2 0 Pentapeptide repeats (8 copies) Reg_prop PF07494.6 ETO02370.1 - 0.036 14.0 1.2 36 4.8 0.0 4.8 5 0 0 5 5 5 0 Two component regulator propeller NYD-SP28_assoc PF14775.1 ETO02370.1 - 0.34 10.6 2.1 90 2.8 0.0 4.3 5 0 0 5 5 4 0 Sperm tail C-terminal domain UPF0506 PF11703.3 ETO02370.1 - 0.49 10.3 2.6 22 5.1 0.0 4.1 5 0 0 5 5 5 0 UPF0506 Peptidase_S29 PF02907.10 ETO02370.1 - 0.61 9.5 4.5 63 3.0 0.0 4.1 2 1 2 4 4 4 0 Hepatitis C virus NS3 protease Ricin_B_lectin PF00652.17 ETO02370.1 - 0.81 9.7 4.5 2.7 8.0 0.2 3.0 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain DUF1356 PF07092.7 ETO02371.1 - 0.029 13.5 1.6 0.037 13.2 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1356) ecTbetaR2 PF08917.5 ETO02372.1 - 0.025 14.3 0.6 0.057 13.1 0.4 1.6 1 0 0 1 1 1 0 Transforming growth factor beta receptor 2 ectodomain FimH_man-bind PF09160.5 ETO02372.1 - 0.091 12.5 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 FimH, mannose binding DUF3464 PF11947.3 ETO02373.1 - 6.8 6.1 8.4 6.4 6.2 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) YqfQ PF14181.1 ETO02373.1 - 8.1 6.4 8.5 7.7 6.5 5.9 1.1 1 0 0 1 1 1 0 YqfQ-like protein WD40 PF00400.27 ETO02374.1 - 0.00084 19.1 0.7 0.0033 17.2 0.7 1.8 2 0 0 2 2 2 1 WD domain, G-beta repeat HSP90 PF00183.13 ETO02376.1 - 1.5e-54 185.3 5.6 1.8e-54 185.0 3.9 1.0 1 0 0 1 1 1 1 Hsp90 protein PPV_E1_C PF00519.12 ETO02376.1 - 0.0063 15.1 0.1 0.0081 14.8 0.1 1.1 1 0 0 1 1 1 1 Papillomavirus helicase DUF2680 PF10925.3 ETO02376.1 - 0.038 13.8 0.1 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) HSP90 PF00183.13 ETO02377.1 - 7.8e-35 120.2 0.3 1.3e-34 119.5 0.2 1.3 1 1 0 1 1 1 1 Hsp90 protein Kelch_4 PF13418.1 ETO02378.1 - 0.0026 17.5 0.1 2.1 8.1 0.0 2.6 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO02378.1 - 0.044 13.5 0.7 0.76 9.6 0.1 2.3 1 1 1 2 2 2 0 Kelch motif WD40 PF00400.27 ETO02379.1 - 6.5e-53 174.8 19.4 9.2e-10 38.0 0.3 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO02379.1 - 8.6e-06 24.1 9.4 0.43 8.6 0.2 5.1 1 1 4 5 5 5 5 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO02379.1 - 2e-05 24.3 1.4 0.082 12.6 0.1 4.1 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 ETO02379.1 - 0.0041 15.9 9.1 0.65 8.6 0.1 3.8 1 1 2 3 3 3 3 Nup133 N terminal like Marek_SORF3 PF07153.6 ETO02379.1 - 0.011 14.3 1.6 3.8 6.1 0.1 3.1 2 1 1 3 3 3 0 Marek's disease-like virus SORF3 protein DUF3601 PF12208.3 ETO02379.1 - 0.035 14.0 0.1 4.9 7.1 0.0 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF3601) HAD PF12710.2 ETO02379.1 - 0.043 13.9 1.9 11 6.0 0.5 2.9 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase NPR3 PF03666.8 ETO02380.1 - 0.018 13.5 2.5 0.022 13.2 1.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Serinc PF03348.10 ETO02380.1 - 0.042 12.5 2.2 0.043 12.5 1.1 1.4 1 1 0 1 1 1 0 Serine incorporator (Serinc) BLVR PF06375.6 ETO02380.1 - 2 8.1 17.2 3.9 7.2 11.9 1.4 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) DUF912 PF06024.7 ETO02380.1 - 6.3 6.9 11.8 0.68 10.0 0.3 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Ecm33 PF12454.3 ETO02381.1 - 0.056 13.3 0.1 0.15 11.9 0.1 1.7 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Dus PF01207.12 ETO02382.1 - 2.2e-44 151.5 0.5 2.5e-44 151.3 0.3 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 ETO02382.1 - 5e-05 22.6 0.0 0.00015 21.0 0.0 1.6 1 1 0 1 1 1 1 Histidine biosynthesis protein DUF849 PF05853.7 ETO02382.1 - 0.0087 14.9 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic protein of unknown function (DUF849) TMP-TENI PF02581.12 ETO02382.1 - 0.0091 15.1 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI DHO_dh PF01180.16 ETO02382.1 - 0.057 12.3 0.0 1.7 7.5 0.0 2.1 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase Pox_E8 PF03394.8 ETO02382.1 - 0.14 11.5 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus E8 protein NMO PF03060.10 ETO02382.1 - 0.16 11.1 0.0 8.7 5.3 0.0 2.1 1 1 1 2 2 2 0 Nitronate monooxygenase EBP PF05241.7 ETO02383.1 - 0.12 11.3 0.1 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Emopamil binding protein Cys_rich_VLP PF14194.1 ETO02384.1 - 1.5 8.6 5.2 1 9.1 0.5 2.2 2 0 0 2 2 2 0 Cysteine-rich VLP Cpn60_TCP1 PF00118.19 ETO02385.1 - 1.5e-38 132.6 0.1 3.9e-32 111.5 0.0 2.0 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family DUF3445 PF11927.3 ETO02387.1 - 0.02 14.2 1.0 0.91 8.8 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3445) GTP_CH_N PF12471.3 ETO02387.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 GTP cyclohydrolase N terminal CAP_GLY PF01302.20 ETO02388.1 - 3.1e-05 23.5 2.0 7e-05 22.4 0.1 2.2 2 0 0 2 2 2 1 CAP-Gly domain PufQ PF05398.6 ETO02388.1 - 2.5 8.2 4.4 12 5.9 0.2 3.0 3 0 0 3 3 3 0 PufQ cytochrome subunit Sigma70_ner PF04546.8 ETO02389.1 - 0.00016 21.3 3.5 0.00022 20.9 2.5 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region Sporozoite_P67 PF05642.6 ETO02389.1 - 0.00022 19.2 0.9 0.00027 18.9 0.6 1.0 1 0 0 1 1 1 1 Sporozoite P67 surface antigen CobT PF06213.7 ETO02389.1 - 0.0061 15.7 9.4 0.0083 15.2 6.5 1.1 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT YL1 PF05764.8 ETO02389.1 - 0.0097 15.5 12.4 0.014 15.0 8.6 1.1 1 0 0 1 1 1 1 YL1 nuclear protein PBP1_TM PF14812.1 ETO02389.1 - 0.014 15.6 15.1 0.028 14.7 10.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RRN3 PF05327.6 ETO02389.1 - 0.016 13.3 1.7 0.017 13.2 1.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF1510 PF07423.6 ETO02389.1 - 0.019 14.3 6.9 0.029 13.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Tim54 PF11711.3 ETO02389.1 - 0.027 13.0 0.5 0.035 12.6 0.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TIMELESS_C PF05029.8 ETO02389.1 - 0.039 12.9 5.7 0.05 12.5 4.0 1.1 1 0 0 1 1 1 0 Timeless protein C terminal region TRAP_alpha PF03896.11 ETO02389.1 - 0.055 12.4 4.3 0.075 12.0 2.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2722 PF10846.3 ETO02389.1 - 0.06 12.3 2.1 0.063 12.2 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Herpes_gE PF02480.11 ETO02389.1 - 0.06 11.6 0.2 0.077 11.2 0.1 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SspB PF04386.8 ETO02389.1 - 0.064 12.8 2.3 0.09 12.3 1.6 1.2 1 0 0 1 1 1 0 Stringent starvation protein B HSP90 PF00183.13 ETO02389.1 - 0.091 11.1 10.2 0.12 10.7 7.1 1.1 1 0 0 1 1 1 0 Hsp90 protein Cnd2 PF05786.9 ETO02389.1 - 0.11 10.9 8.2 0.15 10.5 5.7 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 YqfQ PF14181.1 ETO02389.1 - 0.14 12.1 2.7 0.21 11.6 1.8 1.2 1 0 0 1 1 1 0 YqfQ-like protein CDC45 PF02724.9 ETO02389.1 - 0.2 9.6 10.2 0.26 9.2 7.1 1.1 1 0 0 1 1 1 0 CDC45-like protein VID27 PF08553.5 ETO02389.1 - 0.24 9.6 8.6 0.3 9.2 6.0 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein SMN PF06003.7 ETO02389.1 - 0.26 10.3 3.8 0.35 9.9 2.7 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) WBS_methylT PF12589.3 ETO02389.1 - 0.28 11.6 4.8 0.49 10.9 3.3 1.3 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome Vfa1 PF08432.5 ETO02389.1 - 0.41 10.6 8.8 0.55 10.2 6.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FAM176 PF14851.1 ETO02389.1 - 0.41 10.3 2.6 0.64 9.6 1.8 1.3 1 0 0 1 1 1 0 FAM176 family DUF2890 PF11081.3 ETO02389.1 - 0.49 10.4 6.5 0.72 9.8 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Nop14 PF04147.7 ETO02389.1 - 0.72 7.6 15.8 0.93 7.3 11.0 1.0 1 0 0 1 1 1 0 Nop14-like family SURF2 PF05477.6 ETO02389.1 - 0.76 8.8 10.2 1 8.4 7.1 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) TLP-20 PF06088.6 ETO02389.1 - 1.1 8.9 8.9 1.6 8.3 6.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Daxx PF03344.10 ETO02389.1 - 1.3 7.4 15.8 1.6 7.0 11.0 1.0 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 ETO02389.1 - 1.6 7.3 19.4 2.2 6.8 13.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TFIIF_alpha PF05793.7 ETO02389.1 - 2.3 6.4 15.8 3.2 6.0 10.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CENP-B_dimeris PF09026.5 ETO02389.1 - 2.9 8.2 14.4 6.4 7.0 10.0 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RXT2_N PF08595.6 ETO02389.1 - 3 7.6 10.3 5.1 6.8 7.1 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Dicty_REP PF05086.7 ETO02389.1 - 3.1 5.4 8.0 3.9 5.0 5.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Nucleoplasmin PF03066.10 ETO02389.1 - 4.9 6.6 21.9 7.4 6.0 15.2 1.2 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 ETO02389.1 - 5.2 6.2 13.1 6.4 5.9 9.1 1.1 1 0 0 1 1 1 0 NOA36 protein Pox_RNA_Pol_19 PF05320.7 ETO02389.1 - 6 6.5 10.0 8.9 6.0 7.0 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Dicty_REP PF05086.7 ETO02390.1 - 0.087 10.5 12.6 0.095 10.4 8.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein gpUL132 PF11359.3 ETO02390.1 - 0.19 11.0 13.8 0.28 10.4 9.5 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 Glycophorin_A PF01102.13 ETO02390.1 - 0.21 11.3 7.8 0.33 10.7 5.4 1.3 1 0 0 1 1 1 0 Glycophorin A DUF3484 PF11983.3 ETO02390.1 - 0.47 11.3 6.7 0.65 10.8 4.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3484) Mucin PF01456.12 ETO02390.1 - 0.48 10.1 29.4 0.74 9.5 20.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Plasmodium_Vir PF05795.6 ETO02390.1 - 0.49 9.5 7.0 0.61 9.2 4.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Tim54 PF11711.3 ETO02390.1 - 0.65 8.5 2.9 0.8 8.2 2.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Med3 PF11593.3 ETO02390.1 - 0.86 8.7 16.0 0.88 8.7 11.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CKAP2_C PF15297.1 ETO02390.1 - 1 8.1 5.7 1.2 7.9 3.9 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Herpes_UL47 PF03362.8 ETO02390.1 - 1.5 7.0 4.4 1.8 6.7 3.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL47 protein Macoilin PF09726.4 ETO02390.1 - 5.4 5.1 8.6 5.5 5.1 6.0 1.0 1 0 0 1 1 1 0 Transmembrane protein LmjF365940-deam PF14421.1 ETO02391.1 - 2.4e-29 102.1 0.0 2.7e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 A distinct subfamily of CDD/CDA-like deaminases dCMP_cyt_deam_1 PF00383.17 ETO02391.1 - 0.012 15.1 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region DUF2101 PF09874.4 ETO02392.1 - 0.12 11.8 2.3 0.15 11.5 1.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) PsbX PF06596.6 ETO02392.1 - 0.55 9.9 4.4 0.66 9.6 0.1 2.5 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) Arif-1 PF06770.6 ETO02392.1 - 0.65 9.3 3.5 0.8 9.0 2.4 1.2 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) NfeD PF01957.13 ETO02392.1 - 0.9 9.6 4.4 1.2 9.2 3.1 1.3 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding Apolipoprotein PF01442.13 ETO02393.1 - 0.019 14.4 10.4 0.032 13.7 7.2 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain zf-C3HC4_2 PF13923.1 ETO02393.1 - 0.046 13.7 4.6 0.39 10.7 3.2 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MscS_porin PF12795.2 ETO02393.1 - 0.068 12.4 18.0 0.13 11.5 12.4 1.5 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF1818 PF08848.6 ETO02393.1 - 0.24 11.4 14.0 0.69 9.9 2.0 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF1818) Reo_sigmaC PF04582.7 ETO02393.1 - 0.27 10.3 3.0 0.63 9.1 1.8 1.6 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF641 PF04859.7 ETO02393.1 - 0.63 9.8 16.5 0.057 13.1 1.9 2.7 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) FliL PF03748.9 ETO02393.1 - 2.7 8.0 10.3 0.29 11.1 2.4 2.6 1 1 2 3 3 3 0 Flagellar basal body-associated protein FliL Fib_alpha PF08702.5 ETO02393.1 - 3.9 7.6 25.1 7.8 6.6 6.7 3.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family WD40 PF00400.27 ETO02395.1 - 3.1e-40 134.6 9.7 2.2e-10 39.9 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO02395.1 - 2.5e-06 25.9 0.0 0.012 13.8 0.0 2.8 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO02395.1 - 0.0075 15.0 6.5 0.08 11.6 0.4 2.6 1 1 2 3 3 3 3 Nup133 N terminal like P2 PF07194.6 ETO02397.1 - 0.023 14.5 0.1 0.077 12.8 0.0 1.8 2 0 0 2 2 2 0 P2 response regulator binding domain UPF0278 PF08745.6 ETO02398.1 - 0.0076 15.5 0.0 0.025 13.8 0.0 1.8 1 1 0 1 1 1 1 UPF0278 family ABC_tran PF00005.22 ETO02399.1 - 2.1e-05 24.8 0.1 0.00013 22.3 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.1 ETO02399.1 - 4.1e-05 23.7 0.1 0.0014 18.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 ETO02399.1 - 5.1e-05 23.0 0.0 8.7e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 ETO02399.1 - 0.00019 21.6 0.0 0.00054 20.1 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MCM PF00493.18 ETO02399.1 - 0.0016 17.3 0.1 0.0041 15.9 0.0 1.6 1 1 1 2 2 2 1 MCM2/3/5 family RNA_helicase PF00910.17 ETO02399.1 - 0.0018 18.4 0.1 0.031 14.4 0.0 2.3 2 0 0 2 2 2 1 RNA helicase AAA_17 PF13207.1 ETO02399.1 - 0.0019 19.0 0.1 0.012 16.4 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 ETO02399.1 - 0.0095 16.2 0.4 0.0095 16.2 0.3 2.2 1 1 1 2 2 1 1 AAA domain NACHT PF05729.7 ETO02399.1 - 0.01 15.5 0.2 0.023 14.3 0.1 1.6 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 ETO02399.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Adeno_IVa2 PF02456.10 ETO02399.1 - 0.013 14.1 0.0 0.016 13.8 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_16 PF13191.1 ETO02399.1 - 0.015 15.2 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Arch_ATPase PF01637.13 ETO02399.1 - 0.017 14.7 3.0 0.034 13.8 0.0 2.1 1 1 1 2 2 2 0 Archaeal ATPase Sigma54_activat PF00158.21 ETO02399.1 - 0.018 14.4 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain T2SE PF00437.15 ETO02399.1 - 0.025 13.4 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF258 PF03193.11 ETO02399.1 - 0.025 13.7 0.0 0.045 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF815 PF05673.8 ETO02399.1 - 0.027 13.4 0.2 0.076 11.9 0.0 1.7 1 1 2 3 3 3 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 ETO02399.1 - 0.042 14.1 0.8 0.21 11.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain Bac_DnaA PF00308.13 ETO02399.1 - 0.043 13.4 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein Sigma54_activ_2 PF14532.1 ETO02399.1 - 0.047 13.7 0.0 0.082 12.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 ETO02399.1 - 0.048 13.2 0.4 0.12 11.9 0.0 1.8 2 1 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 ETO02399.1 - 0.059 12.3 0.1 0.13 11.2 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain Glucan_synthase PF02364.10 ETO02399.1 - 0.076 10.8 0.5 0.073 10.9 0.3 1.1 1 0 0 1 1 1 0 1,3-beta-glucan synthase component AAA_8 PF12780.2 ETO02399.1 - 0.089 11.7 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 PduV-EutP PF10662.4 ETO02399.1 - 0.094 12.2 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_2 PF07724.9 ETO02399.1 - 0.12 12.2 0.3 0.44 10.4 0.0 1.9 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 ETO02399.1 - 0.35 10.7 4.3 1.1 9.1 0.0 2.3 1 1 1 2 2 2 0 AAA domain DUF87 PF01935.12 ETO02399.1 - 0.97 9.1 4.0 0.59 9.9 0.1 2.0 1 1 0 2 2 2 0 Domain of unknown function DUF87 Herpes_gE PF02480.11 ETO02400.1 - 0.005 15.1 2.8 0.005 15.1 2.0 1.5 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E SDA1 PF05285.7 ETO02400.1 - 0.2 10.9 13.9 0.32 10.2 9.6 1.3 1 0 0 1 1 1 0 SDA1 SLA_LP_auto_ag PF05889.8 ETO02402.1 - 0.09 11.2 2.1 0.091 11.2 1.5 1.1 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) ATG16 PF08614.6 ETO02402.1 - 0.18 11.6 11.0 0.041 13.7 4.8 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Pox_P35 PF03213.9 ETO02402.1 - 0.29 10.0 2.2 0.32 9.9 1.5 1.2 1 0 0 1 1 1 0 Poxvirus P35 protein DDRGK PF09756.4 ETO02402.1 - 3.5 6.9 14.7 3.4 7.0 9.9 1.3 1 1 0 1 1 1 0 DDRGK domain Protocadherin PF08374.6 ETO02402.1 - 9.5 5.7 7.9 11 5.6 5.5 1.1 1 0 0 1 1 1 0 Protocadherin Kelch_4 PF13418.1 ETO02403.1 - 7.2e-06 25.6 0.1 0.0023 17.6 0.0 2.6 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO02403.1 - 0.0012 18.3 0.3 0.013 15.0 0.1 2.3 2 0 0 2 2 2 1 Kelch motif Tim54 PF11711.3 ETO02403.1 - 0.0038 15.8 0.9 0.0047 15.5 0.6 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Kelch_6 PF13964.1 ETO02403.1 - 0.036 14.2 0.1 0.91 9.8 0.1 2.5 2 0 0 2 2 2 0 Kelch motif CLP_protease PF00574.18 ETO02403.1 - 0.077 12.6 1.2 0.12 12.0 0.8 1.3 1 0 0 1 1 1 0 Clp protease TRAP_alpha PF03896.11 ETO02403.1 - 0.81 8.6 6.9 0.5 9.3 3.7 1.4 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit WD40 PF00400.27 ETO02404.1 - 1.1e-19 69.4 0.3 7.4e-10 38.3 0.0 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO02404.1 - 0.00041 18.6 0.1 0.041 12.0 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Orthopox_A36R PF05950.6 ETO02406.1 - 0.17 11.8 1.0 0.26 11.1 0.1 1.7 1 1 1 2 2 2 0 Orthopoxvirus A36R protein DUF3880 PF12996.2 ETO02406.1 - 0.25 11.2 1.0 5.7 6.9 0.0 2.7 3 0 0 3 3 3 0 DUF based on E. rectale Gene description (DUF3880) TPR_12 PF13424.1 ETO02407.1 - 1.5e-45 153.0 0.8 1.9e-25 88.5 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO02407.1 - 3.9e-26 90.1 0.0 1.5e-08 34.2 0.0 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO02407.1 - 3.4e-23 80.2 4.3 5.9e-09 35.1 0.1 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO02407.1 - 4.3e-22 76.0 0.1 1.9e-08 33.4 0.0 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO02407.1 - 1.9e-21 75.4 0.3 3.5e-12 45.7 0.0 2.1 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.1 ETO02407.1 - 2.8e-16 57.9 11.1 4.9e-07 29.0 0.6 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO02407.1 - 5.6e-15 53.9 1.5 3.7e-05 23.2 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO02407.1 - 9.8e-12 44.1 3.6 8.9e-05 22.4 0.1 3.8 2 2 2 4 4 4 2 Tetratricopeptide repeat MIT PF04212.13 ETO02407.1 - 8.9e-08 31.9 2.1 0.016 15.0 0.1 3.1 3 0 0 3 3 3 3 MIT (microtubule interacting and transport) domain TPR_16 PF13432.1 ETO02407.1 - 7.7e-07 29.6 0.0 0.018 15.7 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO02407.1 - 8.1e-05 22.9 0.0 3.8 8.4 0.0 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO02407.1 - 0.00012 22.2 0.1 6.4 7.4 0.0 3.8 3 2 0 3 3 3 1 Tetratricopeptide repeat SNAP PF14938.1 ETO02407.1 - 0.0007 18.8 0.3 1.1 8.3 0.0 2.1 1 1 0 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_19 PF14559.1 ETO02407.1 - 0.00072 19.8 0.0 0.82 10.0 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO02407.1 - 0.0017 18.4 0.6 1.6 8.9 0.1 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF627 PF04781.7 ETO02407.1 - 0.0031 17.0 0.5 0.22 11.1 0.0 2.6 1 1 2 3 3 3 1 Protein of unknown function (DUF627) PPR PF01535.15 ETO02407.1 - 0.014 15.3 0.6 7.7 6.7 0.1 2.8 3 0 0 3 3 3 0 PPR repeat Fis1_TPR_C PF14853.1 ETO02407.1 - 0.02 14.7 1.0 35 4.3 0.0 3.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat EzrA PF06160.7 ETO02407.1 - 0.061 11.4 0.1 1.1 7.2 0.0 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Rab5-bind PF09311.6 ETO02407.1 - 0.071 13.0 0.0 0.071 12.9 0.0 1.1 1 0 0 1 1 1 0 Rabaptin-like protein Intimin_C PF07979.6 ETO02407.1 - 0.09 12.9 1.0 0.53 10.5 0.2 2.1 1 1 1 2 2 2 0 Intimin C-type lectin domain DNA_primase_S PF01896.14 ETO02410.1 - 0.0042 16.9 0.6 0.0063 16.3 0.4 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit MBOAT_2 PF13813.1 ETO02410.1 - 0.032 14.2 1.6 0.082 12.9 1.1 1.7 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family TPR_12 PF13424.1 ETO02411.1 - 2.9e-50 168.1 16.5 1.3e-21 76.3 2.1 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO02411.1 - 3.5e-28 96.6 0.3 1.2e-07 31.3 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO02411.1 - 3.9e-22 76.8 22.1 2.3e-08 33.2 0.4 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO02411.1 - 9.9e-19 65.6 5.0 5.1e-05 22.7 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO02411.1 - 1e-18 66.7 10.4 7e-11 41.6 4.2 2.6 2 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 ETO02411.1 - 3.8e-17 60.7 10.1 2.4e-05 23.8 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO02411.1 - 6.3e-13 47.4 21.8 0.00021 20.8 0.4 3.5 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO02411.1 - 2e-07 30.6 12.1 0.053 13.7 0.1 4.7 6 1 0 6 6 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO02411.1 - 1.1e-05 25.9 0.1 0.47 11.1 0.0 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO02411.1 - 0.00049 20.4 0.0 5.3 7.9 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat PM0188 PF11477.3 ETO02411.1 - 0.0017 17.2 2.5 0.27 10.0 0.1 2.4 1 1 1 2 2 2 2 Sialyltransferase PMO188 DUF357 PF04010.8 ETO02411.1 - 0.0019 17.8 7.8 0.13 12.0 0.3 3.1 1 1 2 3 3 3 2 Protein of unknown function (DUF357) NSF PF02071.15 ETO02411.1 - 0.0026 17.9 3.9 20 6.3 0.0 4.1 3 0 0 3 3 3 0 Aromatic-di-Alanine (AdAR) repeat Apc3 PF12895.2 ETO02411.1 - 0.0044 17.1 5.7 0.0058 16.7 2.8 1.9 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 Aldo_ket_red PF00248.16 ETO02411.1 - 0.0078 15.0 0.6 0.029 13.2 0.4 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family POR PF01558.13 ETO02411.1 - 0.0083 16.0 0.4 15 5.4 0.0 2.8 1 1 2 3 3 3 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Acetate_kinase PF00871.12 ETO02411.1 - 0.0095 14.5 1.6 1 7.8 0.0 2.8 1 1 2 3 3 3 1 Acetokinase family Syntaxin_2 PF14523.1 ETO02411.1 - 0.0097 15.9 0.0 0.82 9.7 0.0 2.9 2 1 0 2 2 2 1 Syntaxin-like protein Thg1 PF04446.7 ETO02411.1 - 0.016 14.8 0.8 11 5.6 0.0 2.9 1 1 2 3 3 3 0 tRNAHis guanylyltransferase TPR_6 PF13174.1 ETO02411.1 - 0.028 14.8 0.2 61 4.3 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Ten1_2 PF15490.1 ETO02411.1 - 0.028 13.9 0.0 4.8 6.7 0.0 2.8 1 1 2 3 3 3 0 Telomere-capping, CST complex subunit DUF3453 PF11935.3 ETO02411.1 - 0.11 11.9 0.0 12 5.2 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3453) Cytochrom_CIII PF02085.11 ETO02411.1 - 0.13 12.3 0.5 3.9 7.6 0.1 2.1 1 1 1 2 2 2 0 Class III cytochrome C family ATP-synt_E_2 PF08112.6 ETO02411.1 - 0.23 11.5 2.4 12 6.0 0.0 3.1 3 0 0 3 3 3 0 ATP synthase epsilon subunit MIT PF04212.13 ETO02411.1 - 0.41 10.5 7.6 8.5 6.3 0.1 3.1 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 ETO02411.1 - 0.42 10.4 6.8 9.6 6.1 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Swi5 PF07061.6 ETO02411.1 - 6.3 6.6 9.4 19 5.0 0.5 3.1 3 0 0 3 3 3 0 Swi5 CDC45 PF02724.9 ETO02412.1 - 0.11 10.5 11.8 0.13 10.2 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2894 PF11445.3 ETO02412.1 - 0.12 12.6 3.4 0.19 11.9 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) POP1 PF06978.6 ETO02412.1 - 0.61 9.7 10.9 0.52 9.9 6.6 1.5 2 0 0 2 2 2 0 Ribonucleases P/MRP protein subunit POP1 Secretin_N_2 PF07655.8 ETO02412.1 - 0.63 10.4 12.0 1.6 9.1 8.3 1.8 1 0 0 1 1 1 0 Secretin N-terminal domain Menin PF05053.8 ETO02412.1 - 0.88 7.6 14.3 1.2 7.2 9.9 1.2 1 0 0 1 1 1 0 Menin Pox_Ag35 PF03286.9 ETO02412.1 - 1.8 8.0 21.7 2.9 7.3 15.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF3807 PF12720.2 ETO02412.1 - 2.2 8.4 18.4 3.9 7.6 12.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Daxx PF03344.10 ETO02412.1 - 3.1 6.1 21.5 4.3 5.7 14.9 1.1 1 0 0 1 1 1 0 Daxx Family Het-C PF07217.6 ETO02412.1 - 5 5.2 9.7 7 4.7 6.8 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Orbi_VP6 PF01516.11 ETO02413.1 - 3.4 6.6 7.9 3.4 6.6 5.5 1.0 1 0 0 1 1 1 0 Orbivirus helicase VP6 PI3K_rbd PF00794.13 ETO02415.1 - 0.03 14.2 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain DUF4221 PF13970.1 ETO02417.1 - 0.019 14.2 1.3 3.1 7.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4221) Geminin PF07412.7 ETO02418.1 - 0.01 15.5 2.4 0.01 15.5 1.7 2.1 2 0 0 2 2 2 0 Geminin She9_MDM33 PF05546.6 ETO02418.1 - 0.016 14.7 1.3 0.021 14.3 0.9 1.2 1 0 0 1 1 1 0 She9 / Mdm33 family COBRA1 PF06209.8 ETO02418.1 - 0.028 13.0 4.2 0.03 12.9 2.9 1.0 1 0 0 1 1 1 0 Cofactor of BRCA1 (COBRA1) Flavokinase PF01687.12 ETO02418.1 - 0.035 14.0 2.5 0.048 13.5 1.5 1.3 1 1 0 1 1 1 0 Riboflavin kinase DUF869 PF05911.6 ETO02418.1 - 0.041 12.1 5.1 0.058 11.6 3.6 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) DUF641 PF04859.7 ETO02418.1 - 0.061 13.0 3.1 0.11 12.2 2.1 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DivIC PF04977.10 ETO02418.1 - 0.27 10.7 5.3 0.16 11.4 2.4 1.6 2 0 0 2 2 2 0 Septum formation initiator Fib_alpha PF08702.5 ETO02418.1 - 0.45 10.6 8.2 0.83 9.7 5.7 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Bap31 PF05529.7 ETO02418.1 - 1.7 8.0 8.8 2 7.8 5.6 1.4 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like Inhibitor_I29 PF08246.7 ETO02420.1 - 1.3 9.3 9.3 1 9.7 2.0 2.5 2 0 0 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) ELMO_CED12 PF04727.8 ETO02421.1 - 0.044 13.3 0.1 0.055 13.0 0.1 1.4 1 1 0 1 1 1 0 ELMO/CED-12 family PMSR PF01625.16 ETO02421.1 - 0.13 12.1 0.1 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Peptide methionine sulfoxide reductase Folate_carrier PF01770.13 ETO02422.1 - 0.22 10.0 4.7 0.28 9.6 3.2 1.1 1 0 0 1 1 1 0 Reduced folate carrier Folliculin PF11704.3 ETO02422.1 - 0.9 9.0 6.4 1.5 8.4 4.5 1.4 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport U-box PF04564.10 ETO02423.1 - 3e-14 52.7 0.1 6.8e-14 51.5 0.0 1.6 1 1 0 1 1 1 1 U-box domain zf-Nse PF11789.3 ETO02423.1 - 0.024 14.1 0.2 0.057 12.9 0.0 1.8 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit FERM_M PF00373.13 ETO02424.1 - 1.9e-13 50.7 3.9 1.2e-12 48.1 0.3 2.7 2 1 0 2 2 2 1 FERM central domain MyTH4 PF00784.12 ETO02424.1 - 4.2e-11 42.7 0.0 1.6e-10 40.9 0.0 2.1 1 0 0 1 1 1 1 MyTH4 domain RA PF00788.18 ETO02424.1 - 5.8e-06 26.7 0.3 1.5e-05 25.3 0.2 1.7 1 1 0 1 1 1 1 Ras association (RalGDS/AF-6) domain FERM_N PF09379.5 ETO02424.1 - 0.00062 19.7 0.0 0.0014 18.6 0.0 1.7 1 0 0 1 1 1 1 FERM N-terminal domain IRS PF02174.12 ETO02424.1 - 0.0045 16.5 0.1 0.027 14.0 0.0 2.1 2 0 0 2 2 2 1 PTB domain (IRS-1 type) ABC_tran PF00005.22 ETO02425.1 - 4e-13 49.8 0.0 7.5e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 ETO02425.1 - 6.5e-06 25.4 0.0 1.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 ETO02425.1 - 8.1e-05 22.0 0.1 0.00016 21.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 ETO02425.1 - 0.00011 23.0 0.0 0.00021 22.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 ETO02425.1 - 0.00019 21.4 0.0 0.00028 20.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETO02425.1 - 0.00048 20.1 0.0 0.00068 19.6 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 ETO02425.1 - 0.0044 17.3 0.0 0.0078 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 ETO02425.1 - 0.016 15.5 0.0 0.025 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 ETO02425.1 - 0.017 14.8 0.1 0.036 13.7 0.0 1.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 ETO02425.1 - 0.021 14.6 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_22 PF13401.1 ETO02425.1 - 0.025 14.7 0.0 0.06 13.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 ETO02425.1 - 0.039 13.8 0.0 0.1 12.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 ETO02425.1 - 0.045 13.1 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain PRK PF00485.13 ETO02425.1 - 0.054 13.0 0.0 0.53 9.8 0.0 2.0 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_10 PF12846.2 ETO02425.1 - 0.064 12.6 0.1 0.089 12.2 0.1 1.2 1 0 0 1 1 1 0 AAA-like domain IstB_IS21 PF01695.12 ETO02425.1 - 0.076 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.1 ETO02425.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 ETO02425.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain MMR_HSR1 PF01926.18 ETO02425.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.14 ETO02425.1 - 0.13 11.5 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF3987 PF13148.1 ETO02425.1 - 0.14 10.7 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) FtsK_SpoIIIE PF01580.13 ETO02425.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Rad17 PF03215.10 ETO02425.1 - 0.15 10.6 0.0 0.24 10.0 0.0 1.3 1 1 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_30 PF13604.1 ETO02425.1 - 0.17 11.4 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 ETO02425.1 - 0.17 10.7 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein TPR_12 PF13424.1 ETO02426.1 - 7.6e-41 137.9 12.0 3e-24 84.7 1.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO02426.1 - 5.8e-30 102.7 38.8 3.3e-12 45.8 2.1 4.8 1 1 4 5 5 5 5 TPR repeat TPR_1 PF00515.23 ETO02426.1 - 6.4e-24 82.5 30.3 1.8e-07 30.4 0.5 7.1 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO02426.1 - 2.8e-22 76.7 29.9 9.7e-08 31.2 0.5 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETO02426.1 - 8.6e-18 62.7 25.1 3.7e-06 26.4 0.4 6.7 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO02426.1 - 6e-17 60.0 8.5 0.00015 21.2 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO02426.1 - 1.4e-16 59.7 6.2 2.7e-07 30.3 0.0 5.9 6 2 1 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO02426.1 - 3.2e-09 36.6 0.1 0.1 13.3 0.0 5.8 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO02426.1 - 5.2e-09 36.5 0.4 1.8e-05 25.2 0.1 3.5 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO02426.1 - 2.7e-08 33.7 10.2 0.22 12.0 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO02426.1 - 4.3e-08 32.7 11.6 0.69 10.2 0.1 6.3 6 2 1 7 7 6 3 Tetratricopeptide repeat MIT PF04212.13 ETO02426.1 - 5.1e-06 26.2 14.4 0.15 11.9 0.0 5.0 5 0 0 5 5 5 2 MIT (microtubule interacting and transport) domain DUF357 PF04010.8 ETO02426.1 - 0.003 17.2 5.2 0.39 10.4 0.2 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF357) Apc3 PF12895.2 ETO02426.1 - 0.004 17.2 15.1 0.12 12.5 0.5 4.1 2 1 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.4 ETO02426.1 - 0.0049 16.2 9.5 0.2 11.0 0.1 4.3 4 1 1 5 5 5 1 26S proteasome subunit RPN7 PPR PF01535.15 ETO02426.1 - 0.017 15.0 7.4 3.1 7.9 0.0 4.6 5 0 0 5 5 5 0 PPR repeat TPR_3 PF07720.7 ETO02426.1 - 0.058 13.2 18.8 0.12 12.2 1.3 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETO02426.1 - 0.13 12.6 3.7 0.68 10.3 0.2 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat PPR_1 PF12854.2 ETO02426.1 - 0.24 10.9 0.6 1.3 8.5 0.1 2.4 2 0 0 2 2 2 0 PPR repeat Sel1 PF08238.7 ETO02426.1 - 0.65 10.7 0.2 0.65 10.7 0.1 4.0 5 0 0 5 5 3 0 Sel1 repeat MMR_HSR1 PF01926.18 ETO02428.1 - 8.6e-06 25.6 0.6 3.4e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 ETO02428.1 - 7.9e-05 21.8 3.3 0.00014 21.0 0.2 2.7 2 1 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 ETO02428.1 - 0.0031 17.8 0.2 0.0031 17.8 0.2 2.4 1 1 1 2 2 2 1 ABC transporter T2SE PF00437.15 ETO02428.1 - 0.0047 15.8 0.0 0.0093 14.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.11 ETO02428.1 - 0.0091 15.2 0.2 0.02 14.1 0.2 1.6 1 0 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.1 ETO02428.1 - 0.01 15.9 0.3 0.95 9.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 ETO02428.1 - 0.022 14.2 0.1 0.049 13.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.1 ETO02428.1 - 0.042 13.8 0.1 0.13 12.1 0.1 2.0 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 ETO02428.1 - 0.045 13.2 1.0 0.94 8.9 0.1 2.5 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CoA_trans PF01144.18 ETO02428.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Coenzyme A transferase AAA_16 PF13191.1 ETO02428.1 - 0.11 12.4 0.2 0.6 10.0 0.0 2.2 3 0 0 3 3 3 0 AAA ATPase domain Miro PF08477.8 ETO02428.1 - 0.29 11.6 3.8 0.3 11.5 0.2 2.8 1 1 1 2 2 2 0 Miro-like protein PP2C PF00481.16 ETO02429.1 - 2e-54 184.6 0.2 2.3e-54 184.4 0.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 ETO02429.1 - 8.9e-06 25.2 0.0 1.6e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 ETO02429.1 - 2.1e-05 24.3 0.0 8e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) NST1 PF13945.1 ETO02429.1 - 0.15 12.1 2.2 0.26 11.3 1.5 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator MMR_HSR1 PF01926.18 ETO02431.1 - 2.4e-14 53.2 0.1 4.1e-14 52.5 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETO02431.1 - 5.2e-08 32.3 0.1 6.8e-07 28.7 0.1 2.3 3 0 0 3 3 3 1 Ferrous iron transport protein B Dynamin_N PF00350.18 ETO02431.1 - 0.00046 20.0 2.2 0.05 13.4 0.2 2.6 1 1 2 3 3 3 2 Dynamin family DUF258 PF03193.11 ETO02431.1 - 0.0023 17.1 0.5 0.0052 15.9 0.2 1.7 1 1 1 2 2 2 1 Protein of unknown function, DUF258 SRPRB PF09439.5 ETO02431.1 - 0.0053 16.0 0.1 0.0098 15.1 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit CCDC32 PF14989.1 ETO02431.1 - 0.01 15.7 0.1 0.021 14.6 0.1 1.5 1 0 0 1 1 1 1 Coiled-coil domain containing 32 AIG1 PF04548.11 ETO02431.1 - 0.07 12.2 0.2 0.14 11.2 0.1 1.5 1 0 0 1 1 1 0 AIG1 family HEAT PF02985.17 ETO02433.1 - 3.3e-08 32.9 0.0 0.009 16.0 0.0 3.1 3 0 0 3 3 2 2 HEAT repeat HEAT_2 PF13646.1 ETO02433.1 - 9.1e-07 29.0 0.0 2.5e-06 27.6 0.0 1.9 1 1 0 1 1 1 1 HEAT repeats DUF3554 PF12074.3 ETO02433.1 - 0.00013 21.4 2.3 0.00057 19.4 1.6 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3554) HEAT_EZ PF13513.1 ETO02433.1 - 0.00037 20.8 0.0 0.0011 19.3 0.0 1.9 1 0 0 1 1 1 1 HEAT-like repeat DUF3826 PF12875.2 ETO02433.1 - 0.0011 18.7 2.4 0.0011 18.7 1.7 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF3826) NLE PF08154.7 ETO02433.1 - 0.0089 16.0 3.4 2 8.5 0.0 3.6 3 0 0 3 3 3 1 NLE (NUC135) domain Activator-TraM PF11657.3 ETO02433.1 - 0.012 15.0 1.0 0.03 13.8 0.1 2.0 2 0 0 2 2 2 0 Transcriptional activator TraM DUF2608 PF11019.3 ETO02433.1 - 0.022 13.7 6.4 0.042 12.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) RNA_binding PF01877.12 ETO02433.1 - 0.06 13.3 1.0 0.24 11.3 0.1 2.3 1 1 2 3 3 3 0 RNA binding XkdW PF09636.5 ETO02433.1 - 0.35 10.7 3.8 6.3 6.7 0.1 3.0 2 1 1 3 3 3 0 XkdW protein FCH PF00611.18 ETO02433.1 - 0.41 10.8 5.2 5.1 7.3 0.7 3.2 2 2 1 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain MPP6 PF10175.4 ETO02434.1 - 0.004 17.5 1.4 0.016 15.5 0.1 2.3 2 0 0 2 2 2 1 M-phase phosphoprotein 6 DUF4366 PF14283.1 ETO02434.1 - 0.092 12.1 1.3 0.096 12.0 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) TLD PF07534.11 ETO02435.1 - 1.1e-12 48.1 0.5 8.4e-12 45.2 0.1 2.1 2 0 0 2 2 2 1 TLD DUF4611 PF15387.1 ETO02437.1 - 0.027 14.6 1.0 0.041 14.0 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 ETO02437.1 - 0.094 12.2 1.2 0.12 11.9 0.8 1.2 1 0 0 1 1 1 0 Nucleoplasmin DUF3245 PF11595.3 ETO02437.1 - 0.3 11.3 3.0 0.35 11.1 1.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3245) PBP1_TM PF14812.1 ETO02437.1 - 0.47 10.7 6.0 0.91 9.8 4.1 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.6 ETO02437.1 - 1.9 8.2 5.1 1 9.1 2.2 1.5 1 1 0 1 1 1 0 RXT2-like, N-terminal RVT_thumb PF06817.9 ETO02438.1 - 0.00031 20.2 0.8 0.097 12.2 0.2 2.6 2 0 0 2 2 2 2 Reverse transcriptase thumb domain EFhand_Ca_insen PF08726.5 ETO02439.1 - 0.0055 16.6 0.7 0.58 10.1 0.0 2.2 1 1 1 2 2 2 2 Ca2+ insensitive EF hand Pico_P1A PF02226.11 ETO02439.1 - 0.018 14.7 0.1 0.031 14.0 0.1 1.5 1 1 0 1 1 1 0 Picornavirus coat protein (VP4) Y_phosphatase2 PF03162.8 ETO02439.1 - 0.021 14.1 0.7 0.026 13.8 0.3 1.4 1 1 0 1 1 1 0 Tyrosine phosphatase family Mei4 PF13971.1 ETO02439.1 - 0.06 12.2 2.4 0.065 12.1 1.6 1.0 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 Methyltransf_27 PF13708.1 ETO02439.1 - 0.07 12.6 1.8 0.073 12.5 1.3 1.0 1 0 0 1 1 1 0 Methyltransferase domain p25-alpha PF05517.7 ETO02439.1 - 0.15 12.3 2.6 0.91 9.7 0.4 2.0 1 1 1 2 2 2 0 p25-alpha EndoU_bacteria PF14436.1 ETO02439.1 - 0.21 11.4 1.3 0.23 11.3 0.9 1.3 1 1 0 1 1 1 0 Bacterial EndoU nuclease DUF2215 PF10225.4 ETO02439.1 - 0.98 8.8 2.9 1.1 8.6 2.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Pkinase PF00069.20 ETO02440.1 - 0.00013 21.2 0.1 0.0002 20.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO02440.1 - 0.00078 18.5 0.2 0.001 18.1 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RYDR_ITPR PF01365.16 ETO02441.1 - 0.028 13.6 0.5 0.036 13.2 0.3 1.2 1 0 0 1 1 1 0 RIH domain ATP_synth_reg PF14960.1 ETO02441.1 - 0.082 12.1 0.6 3.8 6.7 0.0 2.4 2 0 0 2 2 2 0 ATP synthase regulation CysG_dimeriser PF10414.4 ETO02441.1 - 0.12 11.8 1.3 0.88 9.1 0.1 2.4 2 1 1 3 3 3 0 Sirohaem synthase dimerisation region FlgN PF05130.7 ETO02442.1 - 0.36 11.0 3.1 8.9 6.5 0.6 2.2 2 0 0 2 2 2 0 FlgN protein TSC22 PF01166.13 ETO02442.1 - 1.2 9.1 5.9 2.1 8.3 0.1 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family Kelch_6 PF13964.1 ETO02443.1 - 0.12 12.6 0.1 0.44 10.7 0.0 2.0 2 1 0 2 2 2 0 Kelch motif Cation_ATPase_N PF00690.21 ETO02444.1 - 3.6e-16 58.3 0.0 6.6e-16 57.5 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF1338 PF07063.8 ETO02444.1 - 0.012 14.6 1.9 0.016 14.2 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1338) TMEM156 PF15106.1 ETO02444.1 - 0.18 11.0 1.2 0.22 10.7 0.8 1.1 1 0 0 1 1 1 0 TMEM156 protein family DUF4549 PF15082.1 ETO02444.1 - 1 8.9 4.5 0.74 9.4 1.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4549) DEAD PF00270.24 ETO02445.1 - 2.5e-27 95.4 0.1 2.5e-27 95.4 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 ETO02445.1 - 0.53 10.0 0.0 0.53 10.0 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Neur_chan_memb PF02932.11 ETO02445.1 - 0.87 9.4 4.7 1 9.1 3.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region F-protein PF00469.15 ETO02445.1 - 3 7.1 11.6 4.1 6.7 8.0 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef TRAP_alpha PF03896.11 ETO02446.1 - 0.099 11.6 3.3 0.077 11.9 0.2 1.9 1 1 1 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit RGS PF00615.14 ETO02447.1 - 3.7e-05 23.8 1.7 3.7e-05 23.8 1.2 2.5 2 1 0 2 2 2 1 Regulator of G protein signaling domain Na_H_Exchanger PF00999.16 ETO02447.1 - 0.00087 17.9 10.3 0.0013 17.3 7.1 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family MCR_alpha_N PF02745.10 ETO02447.1 - 0.12 11.5 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, N-terminal domain DUF4064 PF13273.1 ETO02447.1 - 0.21 11.6 6.6 0.84 9.7 0.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) RseC_MucC PF04246.7 ETO02447.1 - 1.6 8.2 9.4 0.14 11.7 0.3 2.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Helicase_C PF00271.26 ETO02448.1 - 5.4e-25 87.0 0.0 1.2e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 ETO02448.1 - 4.8e-07 29.2 0.2 8.5e-07 28.4 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) DEAD PF00270.24 ETO02448.1 - 0.0021 17.5 0.0 0.01 15.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF1443 PF07280.6 ETO02452.1 - 0.39 10.3 3.8 42 3.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1443) Tubulin PF00091.20 ETO02453.1 - 3.4e-25 89.1 0.0 4.1e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO02453.1 - 0.11 12.5 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Tubulin C-terminal domain ABC_tran PF00005.22 ETO02454.1 - 5.8e-06 26.6 0.1 0.00016 22.0 0.0 2.3 2 1 0 2 2 2 1 ABC transporter AAA PF00004.24 ETO02454.1 - 0.00018 21.7 0.0 0.00043 20.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETO02454.1 - 0.0002 21.0 0.0 0.00045 19.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF258 PF03193.11 ETO02454.1 - 0.0013 17.9 0.0 0.0028 16.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 ETO02454.1 - 0.0018 18.7 0.3 0.024 15.1 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 ETO02454.1 - 0.0036 17.4 0.0 0.047 13.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain VWA PF00092.23 ETO02454.1 - 0.0048 16.6 0.0 1.5 8.4 0.0 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain Arch_ATPase PF01637.13 ETO02454.1 - 0.013 15.1 0.1 0.013 15.1 0.1 2.5 2 2 0 2 2 2 0 Archaeal ATPase NACHT PF05729.7 ETO02454.1 - 0.038 13.6 0.1 0.43 10.2 0.0 2.3 2 0 0 2 2 2 0 NACHT domain Transp_Tc5_C PF04236.10 ETO02454.1 - 0.051 13.8 0.8 0.16 12.1 0.1 2.2 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain DUF633 PF04816.7 ETO02454.1 - 0.1 11.9 2.8 4.9 6.4 0.5 2.7 2 1 1 3 3 3 0 Family of unknown function (DUF633) PduV-EutP PF10662.4 ETO02454.1 - 0.11 11.9 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 ETO02454.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ATP-synt_ab PF00006.20 ETO02454.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_21 PF13304.1 ETO02454.1 - 0.38 10.6 0.0 0.38 10.6 0.0 2.8 2 2 0 2 2 2 0 AAA domain AAA_23 PF13476.1 ETO02454.1 - 8.2 6.6 14.0 0.073 13.3 0.4 2.7 2 2 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.2 ETO02458.1 - 0.064 12.2 4.7 0.093 11.7 3.2 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Kei1 PF08552.6 ETO02458.1 - 0.085 12.5 4.8 2.6 7.6 0.0 2.0 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 GSH_synthase PF03199.10 ETO02458.1 - 0.095 12.8 1.3 0.34 11.0 0.1 2.0 2 0 0 2 2 2 0 Eukaryotic glutathione synthase DUF1837 PF08878.6 ETO02458.1 - 0.26 10.8 7.1 0.28 10.7 4.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1837) DUF912 PF06024.7 ETO02458.1 - 0.52 10.3 7.3 0.17 11.9 0.2 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) zf-LITAF-like PF10601.4 ETO02458.1 - 3.9 7.4 5.4 1.9 8.3 0.1 2.8 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain Peptidase_M56 PF05569.6 ETO02459.1 - 0.004 16.1 2.3 0.7 8.7 0.5 2.4 2 0 0 2 2 2 2 BlaR1 peptidase M56 O-antigen_lig PF13425.1 ETO02459.1 - 0.023 14.6 0.9 3.4 7.6 0.2 2.2 2 0 0 2 2 2 0 O-antigen ligase like membrane protein DUF4293 PF14126.1 ETO02459.1 - 0.045 13.6 2.7 0.82 9.5 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) DUF4184 PF13803.1 ETO02459.1 - 0.05 12.9 1.4 0.51 9.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4184) MARVEL PF01284.18 ETO02459.1 - 0.076 12.8 1.8 0.27 11.0 0.1 2.0 2 0 0 2 2 2 0 Membrane-associating domain Wzy_C PF04932.10 ETO02459.1 - 0.2 11.4 1.9 2.3 7.9 0.2 2.3 2 0 0 2 2 2 0 O-Antigen ligase MFS_1 PF07690.11 ETO02459.1 - 0.69 8.5 2.3 5.6 5.5 1.6 1.9 1 1 0 1 1 1 0 Major Facilitator Superfamily Activator-TraM PF11657.3 ETO02460.1 - 0.00057 19.3 0.2 0.00066 19.1 0.1 1.2 1 0 0 1 1 1 1 Transcriptional activator TraM Myosin_head PF00063.16 ETO02461.1 - 7.2e-91 305.2 0.1 8e-91 305.1 0.1 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) REC114-like PF15165.1 ETO02462.1 - 0.041 13.6 0.1 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like YceI PF04264.8 ETO02462.1 - 0.05 13.5 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 YceI-like domain Thioredoxin PF00085.15 ETO02463.1 - 1.4e-09 37.5 0.3 3.1e-09 36.4 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.1 ETO02463.1 - 0.00056 19.8 0.1 0.0022 17.9 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 ETO02463.1 - 0.011 15.8 0.1 0.031 14.4 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin-like domain DIL PF01843.14 ETO02465.1 - 5 7.0 9.4 0.3 10.9 1.5 2.6 3 0 0 3 3 3 0 DIL domain zf-TRAF PF02176.13 ETO02466.1 - 9.4e-05 22.7 5.9 9.4e-05 22.7 4.1 2.8 1 1 2 3 3 3 1 TRAF-type zinc finger Sigma54_AID PF00309.15 ETO02466.1 - 5.3 6.5 8.8 0.64 9.5 2.2 2.3 3 0 0 3 3 3 0 Sigma-54 factor, Activator interacting domain (AID) ATG16 PF08614.6 ETO02467.1 - 0.077 12.8 6.6 0.086 12.6 4.6 1.0 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) WTX PF09422.5 ETO02469.1 - 0.00028 19.9 2.8 0.00033 19.7 2.0 1.0 1 0 0 1 1 1 1 WTX protein HrpJ PF07201.6 ETO02469.1 - 0.02 14.9 6.5 0.023 14.6 4.5 1.1 1 0 0 1 1 1 0 HrpJ-like domain BLVR PF06375.6 ETO02469.1 - 0.26 11.1 10.7 0.25 11.1 7.5 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Sec62 PF03839.11 ETO02469.1 - 0.33 10.3 10.4 0.36 10.2 7.2 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 POX PF07526.6 ETO02469.1 - 0.42 10.8 6.2 0.45 10.7 4.3 1.1 1 0 0 1 1 1 0 Associated with HOX Raftlin PF15250.1 ETO02469.1 - 0.72 8.3 6.0 0.81 8.1 4.2 1.0 1 0 0 1 1 1 0 Raftlin Protocadherin PF08374.6 ETO02469.1 - 0.78 9.3 9.3 0.84 9.2 6.5 1.0 1 0 0 1 1 1 0 Protocadherin NAM-associated PF14303.1 ETO02469.1 - 0.79 10.0 14.1 0.92 9.8 9.8 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF1510 PF07423.6 ETO02469.1 - 1.1 8.5 12.5 1.2 8.5 8.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PBP1_TM PF14812.1 ETO02469.1 - 1.5 9.1 7.5 1.8 8.9 5.2 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_Ag35 PF03286.9 ETO02469.1 - 1.7 8.1 11.0 1.8 8.0 7.6 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Borrelia_P83 PF05262.6 ETO02469.1 - 2.4 6.3 10.9 2.6 6.2 7.6 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Vfa1 PF08432.5 ETO02469.1 - 2.4 8.1 14.5 3 7.8 10.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Gag_spuma PF03276.9 ETO02469.1 - 5.3 5.2 5.5 5.7 5.1 3.8 1.0 1 0 0 1 1 1 0 Spumavirus gag protein Tim54 PF11711.3 ETO02469.1 - 5.3 5.5 8.8 5.8 5.3 6.1 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4407 PF14362.1 ETO02469.1 - 6.9 5.5 7.7 8 5.3 5.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Bap31 PF05529.7 ETO02469.1 - 7.7 5.9 7.5 9.3 5.6 5.2 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Rad17 PF03215.10 ETO02474.1 - 0.05 12.2 1.9 0.058 12.0 1.3 1.0 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein NABP PF07990.7 ETO02474.1 - 0.14 11.4 0.8 0.17 11.1 0.6 1.0 1 0 0 1 1 1 0 Nucleic acid binding protein NABP WD40 PF00400.27 ETO02475.1 - 2.1e-48 160.5 6.3 5.6e-14 51.4 0.0 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat eIF2A PF08662.6 ETO02475.1 - 3e-06 27.0 0.0 0.0018 17.9 0.0 1.9 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO02475.1 - 3.2e-06 26.6 3.2 0.43 10.2 0.0 4.3 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO02475.1 - 1.9e-05 24.2 0.2 7.1e-05 22.3 0.1 2.0 1 1 0 1 1 1 1 PQQ-like domain DUF3601 PF12208.3 ETO02475.1 - 6.7e-05 22.7 0.0 1 9.3 0.0 3.8 1 1 3 4 4 4 1 Domain of unknown function (DUF3601) DUF1652 PF07865.6 ETO02475.1 - 0.011 15.3 0.0 25 4.5 0.0 4.0 2 2 2 4 4 4 0 Protein of unknown function (DUF1652) Cytochrom_D1 PF02239.11 ETO02475.1 - 0.017 13.4 0.2 2.5 6.2 0.0 2.2 1 1 1 2 2 2 0 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 ETO02475.1 - 0.024 13.9 5.7 2.8 7.3 0.1 3.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature PQQ PF01011.16 ETO02475.1 - 0.097 12.2 0.0 9.6 5.9 0.0 3.0 3 0 0 3 3 3 0 PQQ enzyme repeat DUF3312 PF11768.3 ETO02475.1 - 0.098 10.8 0.0 2.1 6.4 0.0 2.5 2 1 0 3 3 3 0 Protein of unknown function (DUF3312) SPT2 PF08243.6 ETO02476.1 - 0.024 14.9 7.2 0.024 14.9 5.0 2.6 3 0 0 3 3 3 0 SPT2 chromatin protein SID-1_RNA_chan PF13965.1 ETO02476.1 - 0.095 10.8 0.1 0.12 10.4 0.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2098 PF09871.4 ETO02476.1 - 1.1 9.2 5.6 2.5 8.0 3.9 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) WD40 PF00400.27 ETO02478.1 - 2.4e-06 27.2 0.2 0.00016 21.4 0.1 2.4 2 1 0 2 2 2 2 WD domain, G-beta repeat Pkinase PF00069.20 ETO02480.1 - 0.00016 20.9 0.3 0.00028 20.1 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain PapB PF03333.8 ETO02482.1 - 0.1 12.4 0.7 0.26 11.1 0.1 1.9 1 1 1 2 2 2 0 Adhesin biosynthesis transcription regulatory protein Spy1 PF11357.3 ETO02482.1 - 0.11 12.6 0.7 0.13 12.3 0.5 1.0 1 0 0 1 1 1 0 Cell cycle regulatory protein ABC2_membrane_3 PF12698.2 ETO02484.1 - 0.00088 18.4 1.0 0.00091 18.3 0.7 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF3270 PF11674.3 ETO02484.1 - 0.15 12.0 3.5 0.23 11.4 2.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3270) PDEase_I_N PF08499.7 ETO02484.1 - 0.18 11.6 1.2 0.36 10.7 0.8 1.6 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal DUF912 PF06024.7 ETO02484.1 - 1.7 8.7 5.0 0.53 10.3 1.2 1.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Flavodoxin_1 PF00258.20 ETO02485.1 - 0.032 14.2 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 Flavodoxin Kelch_4 PF13418.1 ETO02486.1 - 1.4e-05 24.7 0.2 0.0094 15.7 0.0 2.3 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO02486.1 - 0.00046 20.2 1.5 0.0055 16.8 0.1 2.3 1 1 1 2 2 2 1 Kelch motif Kelch_1 PF01344.20 ETO02486.1 - 0.00084 18.8 0.3 0.0094 15.4 0.1 2.1 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO02486.1 - 0.0017 18.4 0.1 0.0066 16.5 0.0 2.0 3 0 0 3 3 3 1 Galactose oxidase, central domain WD40 PF00400.27 ETO02487.1 - 1.1e-32 110.7 11.9 1.7e-10 40.3 0.0 5.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO02487.1 - 5.4e-07 28.1 0.6 0.067 11.3 0.0 3.9 2 1 2 4 4 4 3 Nucleoporin Nup120/160 DUF4550 PF15084.1 ETO02487.1 - 0.011 15.8 0.2 0.041 13.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4550) Nucleoporin_N PF08801.6 ETO02487.1 - 0.22 10.2 3.2 5.9 5.5 1.2 2.8 1 1 0 2 2 2 0 Nup133 N terminal like GDA1_CD39 PF01150.12 ETO02488.1 - 5.9e-74 249.1 0.0 9.3e-74 248.4 0.0 1.2 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family UCH PF00443.24 ETO02491.1 - 3.3e-09 36.2 0.5 3.3e-09 36.2 0.3 1.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Kelch_6 PF13964.1 ETO02492.1 - 0.014 15.5 0.9 0.29 11.4 0.0 3.1 2 1 0 2 2 2 0 Kelch motif DUF3905 PF13045.1 ETO02492.1 - 0.087 12.6 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3905) Peptidase_C14 PF00656.17 ETO02493.1 - 6.7e-05 22.7 0.3 8.3e-05 22.3 0.2 1.3 1 0 0 1 1 1 1 Caspase domain MRP-S26 PF14943.1 ETO02494.1 - 0.12 11.8 11.3 0.19 11.2 7.8 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Peptidase_S49_N PF08496.5 ETO02494.1 - 0.87 9.3 6.4 2.2 8.0 4.4 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TPM PF04536.9 ETO02495.1 - 3.5e-11 43.0 0.0 6.1e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase zf-RING_2 PF13639.1 ETO02495.1 - 1.1e-10 41.1 8.2 2.6e-10 39.9 5.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 ETO02495.1 - 6e-09 35.4 7.2 1.3e-08 34.3 5.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO02495.1 - 1.4e-08 34.6 9.1 3.3e-08 33.4 6.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO02495.1 - 9.9e-08 31.5 6.9 1.8e-07 30.6 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 ETO02495.1 - 1.5e-06 27.7 1.7 1.5e-06 27.7 1.2 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 ETO02495.1 - 5.5e-06 26.0 7.5 1.4e-05 24.7 5.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 ETO02495.1 - 0.0013 18.2 8.9 0.0033 16.9 6.1 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 ETO02495.1 - 0.0013 18.4 3.6 0.003 17.3 2.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 ETO02495.1 - 0.0037 17.3 5.9 0.0097 16.0 4.1 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 ETO02495.1 - 0.0042 16.9 11.6 0.046 13.5 8.0 2.4 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Rtf2 PF04641.7 ETO02495.1 - 0.0067 15.6 0.5 0.0067 15.6 0.3 1.6 2 0 0 2 2 2 1 Rtf2 RING-finger zf-UDP PF14569.1 ETO02495.1 - 0.013 15.2 2.5 0.036 13.8 1.7 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger DUF1244 PF06844.6 ETO02495.1 - 0.15 11.9 1.7 0.3 10.9 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) zf-RING_6 PF14835.1 ETO02495.1 - 3.8 7.3 7.4 1.4 8.7 2.3 2.2 1 1 1 2 2 2 0 zf-RING of BARD1-type protein TPM PF04536.9 ETO02496.1 - 4.6e-11 42.6 0.0 7.7e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase zf-RING_2 PF13639.1 ETO02496.1 - 1.2e-10 41.0 8.5 3.8e-10 39.4 5.9 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO02496.1 - 8.1e-09 35.3 8.9 2.3e-08 33.8 6.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO02496.1 - 1.4e-08 34.2 7.4 3.5e-08 32.9 5.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO02496.1 - 2.9e-07 30.0 7.8 6.7e-07 28.8 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 ETO02496.1 - 3.1e-06 26.7 4.0 1.7e-05 24.4 2.6 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 ETO02496.1 - 6.5e-06 25.7 8.7 1.2e-05 24.9 5.4 2.1 1 1 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 ETO02496.1 - 0.0011 18.7 3.9 0.0024 17.6 2.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 ETO02496.1 - 0.0022 18.0 7.7 0.0022 18.0 5.4 2.1 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_4 PF14570.1 ETO02496.1 - 0.0088 15.6 9.2 0.0088 15.6 6.4 2.1 2 0 0 2 2 1 1 RING/Ubox like zinc-binding domain Rtf2 PF04641.7 ETO02496.1 - 0.017 14.3 0.7 0.025 13.7 0.5 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger zf-C3HC4_4 PF15227.1 ETO02496.1 - 0.017 14.9 10.4 0.017 14.9 7.2 2.8 2 1 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-UDP PF14569.1 ETO02496.1 - 0.052 13.3 3.3 0.11 12.3 2.3 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger DUF1244 PF06844.6 ETO02496.1 - 0.14 12.0 2.4 0.28 11.0 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) zf-RING_6 PF14835.1 ETO02496.1 - 0.19 11.5 6.7 0.12 12.1 1.0 2.5 1 1 0 2 2 2 0 zf-RING of BARD1-type protein TRIQK PF15168.1 ETO02496.1 - 0.27 11.1 1.4 0.77 9.7 1.0 1.7 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family zf-Nse PF11789.3 ETO02496.1 - 1.5 8.3 5.5 5.7 6.5 3.8 2.0 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DZR PF12773.2 ETO02496.1 - 2.7 7.8 11.4 19 5.1 6.3 2.5 1 1 1 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 ETO02496.1 - 3.3 7.4 6.8 2.2 8.0 1.8 2.3 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Cation_ATPase_C PF00689.16 ETO02497.1 - 0.0075 15.8 3.2 0.0088 15.5 2.2 1.2 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus TPR_12 PF13424.1 ETO02498.1 - 5.4e-09 35.8 0.1 6.2e-07 29.2 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO02498.1 - 1.3e-07 30.9 0.3 7.2e-06 25.3 0.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO02498.1 - 2.7e-06 26.8 1.0 0.00041 20.0 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO02498.1 - 3.7e-06 26.4 0.4 1.7e-05 24.3 0.2 2.0 1 1 0 1 1 1 1 TPR repeat TPR_10 PF13374.1 ETO02498.1 - 0.00017 21.3 0.0 0.00039 20.2 0.0 1.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO02498.1 - 0.00046 19.7 0.1 0.014 15.1 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO02498.1 - 0.00047 19.7 0.5 0.012 15.3 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat HEPN PF05168.9 ETO02498.1 - 0.041 13.7 0.1 0.066 13.1 0.1 1.3 1 0 0 1 1 1 0 HEPN domain Gcw_chp PF09694.5 ETO02498.1 - 0.078 12.7 0.8 0.099 12.4 0.6 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (Gcw_chp) RNB PF00773.14 ETO02499.1 - 3.7e-31 108.6 0.1 4.2e-31 108.4 0.0 1.0 1 0 0 1 1 1 1 RNB domain DUF3394 PF11874.3 ETO02500.1 - 0.077 12.5 0.1 0.09 12.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) Peptidase_C14 PF00656.17 ETO02501.1 - 4.2e-11 43.0 0.3 6.1e-11 42.4 0.2 1.3 1 0 0 1 1 1 1 Caspase domain HEAT PF02985.17 ETO02502.1 - 2.4e-10 39.5 0.0 1.1 9.5 0.0 7.1 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 ETO02502.1 - 3.5e-10 40.0 0.0 0.064 13.5 0.0 6.0 2 1 4 6 6 6 4 HEAT repeats Ank_2 PF12796.2 ETO02502.1 - 9.3e-07 29.1 2.7 5.7e-06 26.5 0.0 3.5 4 1 0 4 4 4 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO02502.1 - 1.8e-06 28.2 0.3 6.8e-06 26.4 0.2 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO02502.1 - 3.2e-05 23.7 0.6 0.0067 16.5 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.25 ETO02502.1 - 8.1e-05 22.2 0.0 0.00046 19.8 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat HEAT_EZ PF13513.1 ETO02502.1 - 0.00066 20.0 0.0 39 4.8 0.0 6.3 6 0 0 6 6 6 0 HEAT-like repeat Ank_5 PF13857.1 ETO02502.1 - 0.0079 16.4 0.0 0.041 14.1 0.0 2.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) GlutR_dimer PF00745.15 ETO02502.1 - 0.11 12.4 10.8 3.6 7.5 0.1 5.6 6 0 0 6 6 6 0 Glutamyl-tRNAGlu reductase, dimerisation domain NLE PF08154.7 ETO02502.1 - 0.41 10.6 9.8 16 5.5 0.1 5.4 5 0 0 5 5 5 0 NLE (NUC135) domain ABC_tran PF00005.22 ETO02505.1 - 0.0015 18.8 2.5 0.016 15.5 0.1 2.1 1 1 1 2 2 2 1 ABC transporter DUF2813 PF11398.3 ETO02505.1 - 0.012 14.7 0.4 0.015 14.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) DUF2087 PF09860.4 ETO02505.1 - 0.028 14.1 0.1 0.049 13.3 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) AAA_16 PF13191.1 ETO02505.1 - 0.034 14.1 0.1 0.063 13.2 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 ETO02505.1 - 0.042 13.9 1.1 0.94 9.6 0.3 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 ETO02505.1 - 0.067 12.6 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain MCM PF00493.18 ETO02505.1 - 0.14 10.8 0.5 0.44 9.3 0.1 1.8 1 1 1 2 2 2 0 MCM2/3/5 family NACHT PF05729.7 ETO02505.1 - 0.15 11.6 1.0 0.43 10.2 0.2 2.0 2 1 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 ETO02505.1 - 0.25 11.0 3.0 0.53 9.9 0.3 2.0 1 1 1 2 2 2 0 Archaeal ATPase AAA_18 PF13238.1 ETO02505.1 - 0.51 10.6 3.5 13 6.0 0.2 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 ETO02505.1 - 4.3 7.6 10.0 0.9 9.8 0.2 2.1 1 1 1 2 2 2 0 AAA domain CH PF00307.26 ETO02507.1 - 9.7e-08 32.0 0.2 4.8e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Calponin homology (CH) domain GSH-S_ATP PF02955.11 ETO02508.1 - 2.4e-56 189.5 0.6 2.4e-56 189.5 0.4 2.1 2 0 0 2 2 2 1 Prokaryotic glutathione synthetase, ATP-grasp domain N6_Mtase PF02384.11 ETO02508.1 - 8e-42 143.4 3.0 2.4e-41 141.8 0.6 2.5 2 1 0 2 2 2 1 N-6 DNA Methylase GSH-S_N PF02951.9 ETO02508.1 - 2.4e-28 98.3 0.0 3.6e-27 94.5 0.0 2.5 2 0 0 2 2 2 1 Prokaryotic glutathione synthetase, N-terminal domain RimK PF08443.6 ETO02508.1 - 3.5e-15 55.9 0.3 1.3e-14 54.0 0.2 2.0 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Methyltransf_26 PF13659.1 ETO02508.1 - 2.3e-11 43.7 0.0 1.4e-10 41.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 ETO02508.1 - 9e-07 28.6 0.0 1.8e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methylase_S PF01420.14 ETO02508.1 - 1.4e-05 25.1 0.2 1.4e-05 25.1 0.2 3.5 3 1 0 3 3 3 1 Type I restriction modification DNA specificity domain Eco57I PF07669.6 ETO02508.1 - 0.00099 19.4 0.1 0.0033 17.7 0.1 1.9 1 0 0 1 1 1 1 Eco57I restriction-modification methylase MTS PF05175.9 ETO02508.1 - 0.0011 18.3 0.0 0.0079 15.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 ETO02508.1 - 0.0013 18.2 0.1 0.0041 16.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ATPgrasp_YheCD PF14398.1 ETO02508.1 - 0.028 13.2 2.9 0.071 11.9 0.1 2.6 2 0 0 2 2 2 0 YheC/D like ATP-grasp Methyltransf_18 PF12847.2 ETO02508.1 - 0.046 14.3 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Asn_synthase PF00733.16 ETO02509.1 - 1e-07 31.7 0.0 1.2e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.12 ETO02509.1 - 0.0044 15.9 0.0 0.0051 15.7 0.0 1.1 1 0 0 1 1 1 1 NAD synthase FAM176 PF14851.1 ETO02510.1 - 0.2 11.3 2.0 0.28 10.8 1.4 1.2 1 0 0 1 1 1 0 FAM176 family TPR_12 PF13424.1 ETO02511.1 - 3.4e-30 103.8 14.0 7.4e-18 64.2 0.3 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO02511.1 - 7.7e-23 79.9 17.2 1.2e-11 44.0 2.3 3.1 3 1 0 3 3 3 2 TPR repeat TPR_10 PF13374.1 ETO02511.1 - 2.1e-17 62.4 0.2 1.4e-05 24.8 0.0 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO02511.1 - 3.1e-14 51.5 5.7 0.00052 19.6 0.0 5.2 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO02511.1 - 8.3e-13 47.3 32.2 4.3e-05 22.9 0.5 6.1 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO02511.1 - 1.6e-12 46.2 22.3 2.5e-05 23.8 0.4 5.6 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO02511.1 - 1.7e-07 30.5 30.4 0.00033 20.2 1.4 6.2 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO02511.1 - 0.00021 21.6 0.0 1.4 9.8 0.0 3.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO02511.1 - 0.00043 20.8 0.0 0.6 10.8 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO02511.1 - 0.0013 17.9 1.4 3.7 6.8 0.0 4.1 4 0 0 4 4 4 1 SHNi-TPR Apc3 PF12895.2 ETO02511.1 - 0.0021 18.1 14.4 0.24 11.5 4.4 3.1 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 ETO02511.1 - 0.0024 17.6 9.6 0.031 14.0 3.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO02511.1 - 0.0049 16.9 15.4 0.41 10.9 0.0 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO02511.1 - 0.019 15.3 2.9 2.8 8.5 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.4 ETO02511.1 - 4.8 6.5 20.0 2.3 7.5 0.1 3.9 2 1 1 4 4 4 0 26S proteasome subunit RPN7 DUF3161 PF11362.3 ETO02512.1 - 0.08 12.8 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3161) LAP1C PF05609.7 ETO02515.1 - 0.072 11.7 0.5 0.084 11.5 0.4 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) TLD PF07534.11 ETO02516.1 - 1.2e-17 64.1 5.4 8.1e-16 58.2 1.3 2.8 2 0 0 2 2 2 2 TLD HPPK PF01288.15 ETO02516.1 - 0.0054 16.4 2.5 0.0054 16.4 1.8 1.9 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) G-gamma PF00631.17 ETO02516.1 - 0.008 15.9 1.7 0.02 14.6 0.5 2.2 2 0 0 2 2 2 1 GGL domain Cytochrom_C_2 PF01322.15 ETO02518.1 - 0.02 15.4 1.1 0.02 15.4 0.8 2.4 2 0 0 2 2 2 0 Cytochrome C' Peptidase_M24 PF00557.19 ETO02519.1 - 2.9e-42 144.5 0.1 3.5e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 GAGA_bind PF06217.7 ETO02520.1 - 0.021 14.7 8.5 0.03 14.2 5.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family FHIPEP PF00771.15 ETO02520.1 - 0.033 12.5 1.3 0.14 10.5 0.1 1.9 2 0 0 2 2 2 0 FHIPEP family FGF-BP1 PF06473.7 ETO02520.1 - 0.13 11.7 6.5 0.26 10.8 4.5 1.4 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Ribosomal_60s PF00428.14 ETO02520.1 - 6.6 7.2 12.5 13 6.2 5.1 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Peptidase_S49 PF01343.13 ETO02521.1 - 0.00014 21.6 0.0 0.00015 21.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase family S49 FadA PF09403.5 ETO02521.1 - 0.095 12.7 0.2 0.1 12.6 0.1 1.2 1 0 0 1 1 1 0 Adhesion protein FadA HD_3 PF13023.1 ETO02523.1 - 0.024 14.3 3.0 0.028 14.1 1.2 1.6 1 1 1 2 2 2 0 HD domain Utp12 PF04003.7 ETO02523.1 - 0.039 13.8 0.9 0.17 11.8 0.2 1.9 2 0 0 2 2 2 0 Dip2/Utp12 Family MSC PF09402.5 ETO02523.1 - 0.094 11.4 4.1 0.15 10.7 2.8 1.3 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain HR1 PF02185.11 ETO02523.1 - 0.12 12.1 8.0 0.37 10.5 5.6 1.8 1 1 0 1 1 1 0 Hr1 repeat RRF PF01765.14 ETO02523.1 - 1.1 8.7 9.4 2.7 7.4 0.7 2.4 3 0 0 3 3 3 0 Ribosome recycling factor RNA_pol_Rpb1_5 PF04998.12 ETO02524.1 - 2.1 7.5 9.7 2.8 7.1 6.8 1.3 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 5 HlyC PF02794.11 ETO02525.1 - 0.013 15.0 0.0 0.032 13.8 0.0 1.6 1 0 0 1 1 1 0 RTX toxin acyltransferase family Pathogen_betaC1 PF09593.5 ETO02525.1 - 0.029 14.0 0.8 0.07 12.8 0.5 1.7 1 1 0 1 1 1 0 Beta-satellite pathogenicity beta C1 protein CAP_GLY PF01302.20 ETO02526.1 - 0.01 15.5 0.0 0.028 14.0 0.0 1.8 2 0 0 2 2 2 0 CAP-Gly domain DASH_Dad3 PF08656.5 ETO02526.1 - 0.098 12.3 0.4 0.63 9.7 0.2 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 Snapin_Pallidin PF14712.1 ETO02526.1 - 2.8 8.3 6.8 0.23 11.7 1.1 1.8 2 0 0 2 2 2 0 Snapin/Pallidin NACHT PF05729.7 ETO02527.1 - 1.1e-06 28.4 0.0 2.6e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain FPL PF09758.4 ETO02528.1 - 4e-05 23.4 3.5 0.015 15.0 0.1 2.7 1 1 2 3 3 3 2 Uncharacterised conserved protein Adaptin_N PF01602.15 ETO02528.1 - 0.0073 14.6 0.9 0.0086 14.4 0.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region MIF4G PF02854.14 ETO02528.1 - 0.015 14.6 4.0 0.19 11.1 0.2 2.2 1 1 0 2 2 2 0 MIF4G domain HEAT_2 PF13646.1 ETO02528.1 - 0.078 13.2 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 HEAT repeats HEAT PF02985.17 ETO02528.1 - 0.13 12.3 0.0 0.63 10.2 0.0 2.2 2 0 0 2 2 2 0 HEAT repeat HEAT_2 PF13646.1 ETO02529.1 - 2.9e-21 75.5 0.0 1.2e-05 25.5 0.0 6.5 4 2 3 7 7 7 5 HEAT repeats HEAT PF02985.17 ETO02529.1 - 2.7e-14 51.8 2.4 0.85 9.8 0.0 9.7 10 0 0 10 10 10 3 HEAT repeat Cnd1 PF12717.2 ETO02529.1 - 5.1e-12 45.9 19.7 9.9e-06 25.5 0.5 4.4 1 1 1 3 3 3 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 ETO02529.1 - 8.6e-09 35.6 0.0 0.44 11.1 0.0 7.6 7 4 3 10 10 10 1 HEAT-like repeat Ank_3 PF13606.1 ETO02529.1 - 7.5e-06 25.7 0.3 0.00019 21.3 0.0 3.6 4 0 0 4 4 3 1 Ankyrin repeat Vac14_Fab1_bd PF12755.2 ETO02529.1 - 8.3e-06 26.1 16.9 0.018 15.4 0.1 6.6 3 2 3 6 6 6 2 Vacuolar 14 Fab1-binding region Ank_2 PF12796.2 ETO02529.1 - 0.00085 19.6 0.2 0.008 16.4 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Arm PF00514.18 ETO02529.1 - 0.0022 17.7 0.1 22 5.0 0.0 4.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Ank PF00023.25 ETO02529.1 - 0.039 13.7 0.1 0.21 11.4 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.1 ETO02529.1 - 0.039 14.2 0.1 0.29 11.4 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) HEAT_PBS PF03130.11 ETO02529.1 - 0.16 12.5 0.0 1.5e+02 3.2 0.0 4.1 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat Ank_4 PF13637.1 ETO02529.1 - 0.2 12.1 1.7 4.6 7.8 0.1 3.8 4 0 0 4 4 4 0 Ankyrin repeats (many copies) ALMT PF11744.3 ETO02530.1 - 0.003 16.2 1.4 0.0053 15.4 1.0 1.3 1 0 0 1 1 1 1 Aluminium activated malate transporter WD40 PF00400.27 ETO02531.1 - 1.3e-19 69.2 9.5 4.9e-10 38.9 0.5 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO02531.1 - 1.1e-05 23.8 1.1 0.0075 14.4 0.1 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO02531.1 - 0.15 11.3 2.7 1.2 8.4 1.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4221) DUF4637 PF15470.1 ETO02532.1 - 6 6.4 13.3 1.1 8.9 6.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) Ras PF00071.17 ETO02534.1 - 1.8e-11 43.7 0.4 5e-11 42.2 0.0 1.9 2 1 0 2 2 2 1 Ras family mRNA_stabil PF13929.1 ETO02535.1 - 0.04 12.8 0.8 0.044 12.7 0.5 1.1 1 0 0 1 1 1 0 mRNA stabilisation Endothelin PF00322.12 ETO02535.1 - 0.12 11.5 0.4 0.23 10.7 0.3 1.4 1 0 0 1 1 1 0 Endothelin family SPRY PF00622.23 ETO02536.1 - 2.5e-05 24.3 0.1 5.1e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 SPRY domain FYVE PF01363.16 ETO02537.1 - 0.81 9.6 16.7 5.7 6.9 0.3 4.6 4 2 0 4 4 4 0 FYVE zinc finger zf-RING_5 PF14634.1 ETO02537.1 - 6.8 6.5 20.7 0.078 12.7 2.1 4.3 2 1 1 3 3 3 0 zinc-RING finger domain zf-RING_2 PF13639.1 ETO02537.1 - 8.7 6.2 15.1 2.7e+02 1.5 0.0 3.7 2 1 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.1 ETO02538.1 - 0.078 12.7 13.2 0.32 10.7 5.5 3.2 2 1 1 3 3 3 0 zinc-RING finger domain Nudix_N_2 PF14803.1 ETO02538.1 - 0.59 9.8 0.1 0.59 9.8 0.0 3.2 4 0 0 4 4 4 0 Nudix N-terminal DUF2039 PF10217.4 ETO02538.1 - 2.8 8.0 6.5 6.9 6.7 0.0 2.9 2 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2039) Prok-RING_1 PF14446.1 ETO02538.1 - 3.3 7.5 11.6 2.4 7.9 2.0 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-C3HC4_2 PF13923.1 ETO02538.1 - 9.7 6.3 15.5 0.12 12.4 1.9 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.27 ETO02539.1 - 2e-06 27.4 0.4 3.2e-05 23.6 0.1 2.3 2 1 0 2 2 2 1 WD domain, G-beta repeat DUF762 PF05555.6 ETO02539.1 - 0.004 16.4 0.4 0.0047 16.2 0.3 1.1 1 0 0 1 1 1 1 Coxiella burnetii protein of unknown function (DUF762) Nucleoporin_N PF08801.6 ETO02539.1 - 0.081 11.6 0.2 0.12 11.1 0.1 1.3 1 1 0 1 1 1 0 Nup133 N terminal like Pro_3_hydrox_C PF05373.6 ETO02540.1 - 0.027 14.5 1.8 0.033 14.2 0.2 1.9 2 0 0 2 2 2 0 L-proline 3-hydroxylase, C-terminal Hid1 PF12722.2 ETO02542.1 - 0.22 9.1 14.3 0.28 8.7 9.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PUB PF09409.5 ETO02543.1 - 0.0057 16.3 0.2 0.028 14.1 0.1 2.3 1 1 0 1 1 1 1 PUB domain CUE PF02845.11 ETO02543.1 - 0.016 14.6 0.0 0.037 13.5 0.0 1.6 1 0 0 1 1 1 0 CUE domain PBP_GOBP PF01395.17 ETO02543.1 - 0.06 12.9 1.5 0.23 11.0 0.3 2.3 1 1 1 2 2 2 0 PBP/GOBP family His_Phos_1 PF00300.17 ETO02544.1 - 0.023 14.7 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) FF PF01846.14 ETO02545.1 - 0.052 13.5 0.0 0.069 13.1 0.0 1.2 1 0 0 1 1 1 0 FF domain ETRAMP PF09716.5 ETO02545.1 - 2.7 8.0 7.7 48 4.0 5.3 2.1 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) WD40 PF00400.27 ETO02546.1 - 1.2e-11 43.9 0.1 7.2e-05 22.5 0.0 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat eIF2A PF08662.6 ETO02546.1 - 0.00016 21.4 1.3 0.00029 20.6 0.5 1.6 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Mid2 PF04478.7 ETO02546.1 - 0.035 13.5 0.1 0.072 12.4 0.0 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Str_synth PF03088.11 ETO02546.1 - 0.093 12.7 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Strictosidine synthase DUF1484 PF07363.6 ETO02546.1 - 0.13 12.6 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1484) Sorb PF02208.11 ETO02548.1 - 0.098 12.0 0.1 0.29 10.5 0.0 1.8 2 0 0 2 2 2 0 Sorbin homologous domain DUF1840 PF08895.6 ETO02548.1 - 0.11 12.5 0.4 0.13 12.3 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) 7TM_GPCR_Srv PF10323.4 ETO02551.1 - 0.19 10.8 1.2 0.21 10.6 0.8 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv ALS2CR8 PF15299.1 ETO02551.1 - 0.2 11.2 12.2 0.21 11.1 8.5 1.0 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Phage_Gp23 PF10669.4 ETO02551.1 - 0.3 11.1 7.8 0.34 11.0 5.4 1.1 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) BLVR PF06375.6 ETO02551.1 - 0.63 9.8 14.3 0.68 9.7 9.9 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Anoctamin PF04547.7 ETO02551.1 - 1.1 7.8 4.8 0.97 8.0 3.3 1.0 1 0 0 1 1 1 0 Calcium-activated chloride channel ETRAMP PF09716.5 ETO02551.1 - 1.5 8.8 6.5 2.2 8.3 4.5 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Peptidase_S49_N PF08496.5 ETO02551.1 - 1.9 8.3 10.8 1.7 8.4 7.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RNase_H2-Ydr279 PF09468.5 ETO02551.1 - 4.4 6.4 11.7 4 6.5 8.1 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Med19 PF10278.4 ETO02551.1 - 4.4 6.9 17.4 4.4 6.9 12.1 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 WBP-1 PF11669.3 ETO02551.1 - 5.6 7.0 5.7 6.9 6.8 3.5 1.6 1 1 0 1 1 1 0 WW domain-binding protein 1 EF-hand_1 PF00036.27 ETO02553.1 - 1.2e-08 33.6 7.6 0.00011 21.2 0.3 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 ETO02553.1 - 3.9e-07 29.5 7.1 0.00046 19.7 0.3 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.1 ETO02553.1 - 4.2e-07 30.0 1.0 0.011 15.8 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO02553.1 - 4.4e-07 29.2 4.4 0.006 16.3 0.3 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 ETO02553.1 - 0.00029 20.0 4.2 0.02 14.2 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.2 ETO02553.1 - 0.00044 19.9 3.0 0.092 12.4 0.2 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Phostensin_N PF13916.1 ETO02553.1 - 0.46 10.4 0.1 0.46 10.4 0.0 2.0 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal Colicin_im PF03857.8 ETO02554.1 - 0.0065 16.2 0.2 0.0085 15.8 0.2 1.2 1 0 0 1 1 1 1 Colicin immunity protein DUF3899 PF13038.1 ETO02555.1 - 0.0094 16.0 0.5 0.054 13.6 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3899) BCD PF15461.1 ETO02555.1 - 0.031 13.7 3.9 0.044 13.1 2.7 1.2 1 0 0 1 1 1 0 Beta-carotene 15,15'-dioxygenase Paf67 PF10255.4 ETO02555.1 - 0.074 11.9 0.9 0.11 11.3 0.6 1.2 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 zf-TRAF PF02176.13 ETO02557.1 - 1.1e-05 25.7 2.2 1.1e-05 25.7 1.5 3.0 2 1 1 3 3 3 1 TRAF-type zinc finger Sina PF03145.11 ETO02557.1 - 0.0097 15.5 2.7 0.039 13.5 1.8 2.1 1 1 1 2 2 2 2 Seven in absentia protein family TMF_TATA_bd PF12325.3 ETO02557.1 - 0.012 15.3 0.4 0.36 10.5 0.1 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Viral_Rep PF02407.11 ETO02557.1 - 0.046 13.7 0.1 0.16 11.9 0.1 1.9 1 0 0 1 1 1 0 Putative viral replication protein zf-C3HC4 PF00097.20 ETO02557.1 - 0.8 9.4 6.1 10 5.8 0.1 3.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF755 PF05501.6 ETO02557.1 - 1.4 8.9 6.6 0.19 11.8 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DUF1371 PF07115.6 ETO02558.1 - 0.038 14.1 0.3 0.045 13.9 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1371) tRNA_synt_2f PF02092.12 ETO02559.1 - 2.7e-56 191.2 0.0 3.1e-56 191.0 0.0 1.0 1 0 0 1 1 1 1 Glycyl-tRNA synthetase beta subunit Tudor-knot PF11717.3 ETO02560.1 - 0.0028 17.3 1.8 0.0072 16.0 1.3 1.7 1 1 0 1 1 1 1 RNA binding activity-knot of a chromodomain Actin PF00022.14 ETO02561.1 - 0.029 12.7 0.0 0.033 12.6 0.0 1.1 1 0 0 1 1 1 0 Actin DUF3232 PF11554.3 ETO02561.1 - 0.08 12.8 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3232) Chordopox_RPO7 PF05864.7 ETO02562.1 - 1 9.4 4.9 0.89 9.7 0.3 2.2 1 1 1 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Kinesin PF00225.18 ETO02566.1 - 1.5e-28 99.4 0.2 2.3e-28 98.9 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain zf-C4pol PF14260.1 ETO02567.1 - 0.014 15.4 1.9 0.034 14.1 0.4 2.0 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta zf-TFIIB PF13453.1 ETO02567.1 - 0.032 13.4 0.2 0.066 12.4 0.1 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger CUE PF02845.11 ETO02568.1 - 0.002 17.5 0.1 0.0037 16.7 0.1 1.5 1 0 0 1 1 1 1 CUE domain SR-25 PF10500.4 ETO02570.1 - 1.5 8.2 20.6 3.5 7.0 14.3 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein EIIBC-GUT_N PF03612.9 ETO02571.1 - 0.99 8.9 6.6 1.2 8.7 4.6 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus alpha-hel2 PF14456.1 ETO02571.1 - 4.3 6.0 5.1 4.6 5.9 3.5 1.0 1 0 0 1 1 1 0 Alpha-helical domain 2 Pro-MCH PF05824.7 ETO02572.1 - 0.0097 15.3 0.2 0.033 13.6 0.0 1.8 2 0 0 2 2 2 1 Pro-melanin-concentrating hormone (Pro-MCH) DUF1623 PF07785.6 ETO02572.1 - 0.35 10.8 4.7 1.1 9.2 3.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1623) Syntaxin_2 PF14523.1 ETO02572.1 - 0.59 10.1 8.9 0.15 12.1 2.4 2.2 2 1 0 2 2 2 0 Syntaxin-like protein FliJ PF02050.11 ETO02572.1 - 1.3 9.0 14.3 8.2 6.5 0.2 2.5 1 1 1 2 2 2 0 Flagellar FliJ protein DUF948 PF06103.6 ETO02572.1 - 2.5 8.0 5.5 1.7 8.5 0.6 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) MSG PF02349.10 ETO02574.1 - 0.1 12.5 1.6 0.24 11.4 1.1 1.7 1 1 0 1 1 1 0 Major surface glycoprotein BRCT_assoc PF12820.2 ETO02576.1 - 0.042 13.6 0.0 0.095 12.4 0.0 1.5 1 0 0 1 1 1 0 Serine-rich domain associated with BRCT Glyco_transf_5 PF08323.6 ETO02576.1 - 0.042 13.3 0.1 0.071 12.5 0.0 1.4 1 1 0 1 1 1 0 Starch synthase catalytic domain DUF4375 PF14300.1 ETO02579.1 - 0.013 15.5 6.5 0.091 12.7 1.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4375) BLOC1_2 PF10046.4 ETO02579.1 - 0.19 11.8 6.4 0.48 10.5 4.5 1.7 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1018 PF06252.7 ETO02579.1 - 0.81 10.2 5.1 5.3 7.5 3.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) zf-CCHC PF00098.18 ETO02579.1 - 3.5 7.7 6.8 0.44 10.5 0.3 2.6 2 0 0 2 2 2 0 Zinc knuckle UN_NPL4 PF11543.3 ETO02581.1 - 0.0046 17.2 0.1 0.0052 17.0 0.1 1.2 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 PB1 PF00564.19 ETO02581.1 - 0.0066 16.0 0.3 0.0086 15.7 0.2 1.2 1 0 0 1 1 1 1 PB1 domain Gly_acyl_tr_N PF06021.6 ETO02581.1 - 0.038 13.3 0.1 0.038 13.3 0.1 1.1 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase DUF563 PF04577.9 ETO02581.1 - 0.065 13.1 0.0 0.07 13.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF563) DED PF01335.16 ETO02581.1 - 0.088 12.9 0.2 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Death effector domain Pox_A_type_inc PF04508.7 ETO02582.1 - 0.22 11.4 1.5 1.2 9.0 0.5 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Flp_N PF03930.9 ETO02583.1 - 0.075 12.8 2.0 0.14 11.8 0.1 2.0 1 1 1 2 2 2 0 Recombinase Flp protein N-terminus RPW8 PF05659.6 ETO02583.1 - 0.088 12.3 1.6 0.1 12.1 1.1 1.2 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 TROVE PF05731.6 ETO02583.1 - 0.11 11.2 1.8 0.11 11.2 1.3 1.0 1 0 0 1 1 1 0 TROVE domain DUF1837 PF08878.6 ETO02583.1 - 0.11 12.0 6.3 0.14 11.7 4.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1837) Synaptonemal_3 PF15191.1 ETO02583.1 - 0.15 11.7 0.8 0.25 11.1 0.5 1.4 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 FliD_N PF02465.13 ETO02583.1 - 0.23 11.8 1.0 0.58 10.5 0.5 1.7 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus TcdB_N PF12918.2 ETO02583.1 - 1.5 8.9 8.4 0.28 11.3 2.3 2.0 1 1 1 2 2 2 0 TcdB toxin N-terminal helical domain SSXT PF05030.7 ETO02583.1 - 1.7 8.3 8.2 1.3 8.6 1.4 2.6 1 1 2 3 3 3 0 SSXT protein (N-terminal region) bZIP_1 PF00170.16 ETO02583.1 - 8.1 6.4 10.2 0.46 10.4 3.1 1.8 2 0 0 2 2 2 0 bZIP transcription factor FAINT PF04385.10 ETO02584.1 - 0.58 10.0 3.8 6.2 6.7 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function, DUF529 C1-set PF07654.10 ETO02585.1 - 0.11 12.5 0.9 0.28 11.2 0.2 2.0 2 1 0 2 2 2 0 Immunoglobulin C1-set domain ABC_tran PF00005.22 ETO02586.1 - 1.4e-12 48.0 0.0 1.6e-12 47.9 0.0 1.0 1 0 0 1 1 1 1 ABC transporter TPR_12 PF13424.1 ETO02587.1 - 1.7e-50 168.8 17.7 5.2e-22 77.5 1.4 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO02587.1 - 6.7e-38 127.5 0.1 6.2e-08 32.3 0.0 6.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.23 ETO02587.1 - 8.1e-36 120.1 45.1 8.3e-10 37.8 0.5 6.7 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 ETO02587.1 - 5e-34 113.4 29.8 7.7e-08 31.6 0.5 6.2 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_11 PF13414.1 ETO02587.1 - 6.4e-33 112.2 34.8 1.7e-16 59.6 3.8 4.9 1 1 3 5 5 5 4 TPR repeat TPR_7 PF13176.1 ETO02587.1 - 3.7e-24 82.5 11.0 7.1e-05 22.3 0.1 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO02587.1 - 1.7e-22 79.5 10.6 8e-07 29.5 0.0 4.3 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO02587.1 - 2.6e-21 73.7 43.1 8.7e-07 28.2 0.2 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_6 PF13174.1 ETO02587.1 - 8.1e-16 57.3 6.6 0.016 15.6 0.1 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO02587.1 - 2.5e-15 55.5 0.0 0.061 13.9 0.0 5.6 5 1 1 6 6 5 3 Tetratricopeptide repeat Apc3 PF12895.2 ETO02587.1 - 1e-11 44.8 28.1 4.1e-05 23.6 6.6 4.8 1 1 4 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 ETO02587.1 - 2.8e-11 42.7 25.5 0.0048 16.9 0.0 6.5 6 2 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO02587.1 - 1.2e-06 28.7 8.0 0.0034 17.6 0.7 4.5 3 1 2 5 5 5 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO02587.1 - 3.1e-06 26.3 2.3 0.35 10.1 0.2 4.2 4 0 0 4 4 4 2 SHNi-TPR DUF2225 PF09986.4 ETO02587.1 - 2.3e-05 23.9 22.2 0.001 18.5 1.8 3.8 1 1 2 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_3 PF07720.7 ETO02587.1 - 4.4e-05 23.1 27.9 0.0089 15.8 0.9 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat MIT PF04212.13 ETO02587.1 - 6.7e-05 22.7 19.6 0.92 9.4 0.1 5.9 6 0 0 6 6 6 2 MIT (microtubule interacting and transport) domain TPR_5 PF12688.2 ETO02587.1 - 8.8e-05 22.5 0.1 0.13 12.2 0.0 3.3 3 0 0 3 3 3 1 Tetratrico peptide repeat PPR PF01535.15 ETO02587.1 - 0.00022 20.9 6.7 0.62 10.1 0.2 5.4 6 0 0 6 6 5 1 PPR repeat mit_SMPDase PF14724.1 ETO02587.1 - 0.01 13.7 0.2 0.015 13.1 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial-associated sphingomyelin phosphodiesterase Mob_Pre PF01076.14 ETO02587.1 - 0.065 12.8 16.6 0.17 11.5 7.1 2.3 1 1 1 2 2 2 0 Plasmid recombination enzyme OEP PF02321.13 ETO02587.1 - 0.093 12.3 9.4 11 5.5 4.6 3.6 2 1 0 3 3 3 0 Outer membrane efflux protein DUF1896 PF08989.5 ETO02587.1 - 0.19 11.6 6.0 0.37 10.6 0.3 3.5 2 1 3 5 5 5 0 Domain of unknown function (DUF1896) Foie-gras_1 PF11817.3 ETO02587.1 - 0.25 10.8 6.0 16 4.9 0.2 3.9 2 2 0 4 4 4 0 Foie gras liver health family 1 RPN7 PF10602.4 ETO02587.1 - 0.29 10.5 17.0 2.8 7.2 0.2 4.6 1 1 2 3 3 3 0 26S proteasome subunit RPN7 Sel1 PF08238.7 ETO02587.1 - 0.37 11.4 16.5 12 6.6 0.0 5.5 6 0 0 6 6 5 0 Sel1 repeat Rapsyn_N PF10579.4 ETO02587.1 - 0.38 10.5 5.3 59 3.5 0.1 4.5 5 1 1 6 6 4 0 Rapsyn N-terminal myristoylation and linker region Prefoldin PF02996.12 ETO02587.1 - 1.2 8.8 12.5 0.76 9.4 0.4 4.1 3 2 2 5 5 5 0 Prefoldin subunit Vps39_1 PF10366.4 ETO02587.1 - 1.5 8.8 12.6 7.8 6.5 0.3 4.1 1 1 2 4 4 3 0 Vacuolar sorting protein 39 domain 1 Neuro_bHLH PF12533.3 ETO02587.1 - 2.5 8.9 6.5 26 5.6 0.1 3.3 1 1 2 3 3 3 0 Neuronal helix-loop-helix transcription factor PPR_2 PF13041.1 ETO02587.1 - 2.8 8.0 13.8 5.6 7.0 0.1 4.9 5 1 0 6 6 6 0 PPR repeat family NSF PF02071.15 ETO02587.1 - 7.5 7.6 22.4 26 5.9 0.1 6.7 6 0 0 6 6 6 0 Aromatic-di-Alanine (AdAR) repeat UCH PF00443.24 ETO02588.1 - 0.0022 17.1 3.0 0.0022 17.1 2.1 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SPRY PF00622.23 ETO02589.1 - 1.4e-13 51.0 0.3 3e-13 49.9 0.2 1.5 1 0 0 1 1 1 1 SPRY domain zf-RanBP PF00641.13 ETO02589.1 - 0.0047 16.0 7.7 0.012 14.6 5.4 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others WD40 PF00400.27 ETO02590.1 - 5.5e-20 70.4 0.1 1.6e-08 34.0 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO02590.1 - 0.029 13.1 1.4 0.49 9.0 0.2 2.0 1 1 0 2 2 2 0 Nup133 N terminal like DUF3637 PF12337.3 ETO02590.1 - 0.031 14.2 0.3 0.055 13.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3637) Nup160 PF11715.3 ETO02590.1 - 0.032 12.3 0.1 2 6.4 0.0 2.0 1 1 0 2 2 2 0 Nucleoporin Nup120/160 Abhydrolase_2 PF02230.11 ETO02593.1 - 3.1e-16 59.4 0.1 4.4e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 ETO02593.1 - 1.3e-05 25.0 0.0 1.7e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETO02593.1 - 0.00022 20.5 0.0 0.0003 20.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 ETO02593.1 - 0.0055 16.0 0.0 0.007 15.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.8 ETO02593.1 - 0.019 14.3 0.0 0.024 14.0 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Neur_chan_memb PF02932.11 ETO02593.1 - 0.024 14.5 0.4 0.029 14.2 0.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Abhydrolase_6 PF12697.2 ETO02593.1 - 0.034 14.0 0.0 1.2 8.9 0.0 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase family WBP-1 PF11669.3 ETO02593.1 - 0.048 13.7 0.1 0.087 12.9 0.1 1.4 1 0 0 1 1 1 0 WW domain-binding protein 1 Abhydrolase_4 PF08386.5 ETO02593.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 TAP-like protein Mannosyl_trans3 PF11051.3 ETO02596.1 - 1.2e-06 28.0 0.0 1.9e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Sulfatase PF00884.18 ETO02597.1 - 0.082 12.0 1.6 1.2 8.2 0.0 2.2 1 1 1 2 2 2 0 Sulfatase Ras PF00071.17 ETO02598.1 - 8.2e-24 83.8 0.0 1.2e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO02598.1 - 0.0013 19.2 0.0 0.0028 18.1 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO02598.1 - 0.025 13.7 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family Ran_BP1 PF00638.13 ETO02600.1 - 2.9e-06 27.3 0.1 5.6e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 RanBP1 domain DUF4611 PF15387.1 ETO02600.1 - 0.0036 17.4 4.6 0.0036 17.4 3.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4611) NPV_P10 PF05531.7 ETO02600.1 - 0.055 13.7 1.0 0.08 13.2 0.1 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein PIG-P PF08510.7 ETO02600.1 - 0.19 11.3 1.2 4.5 6.9 0.2 2.4 2 0 0 2 2 2 0 PIG-P Vfa1 PF08432.5 ETO02600.1 - 1.4 8.8 11.9 0.38 10.7 3.2 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 FAM177 PF14774.1 ETO02600.1 - 6.4 6.7 12.2 0.13 12.1 3.5 1.8 2 0 0 2 2 2 0 FAM177 family zf-DHHC PF01529.15 ETO02602.1 - 6.2e-30 103.8 6.0 6.2e-30 103.8 4.2 2.2 1 1 1 2 2 2 1 DHHC palmitoyltransferase ADH_N PF08240.7 ETO02602.1 - 2.4 7.9 7.7 1.3 8.7 3.6 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain DUF2975 PF11188.3 ETO02602.1 - 3.9 7.2 6.9 0.69 9.6 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Kelch_2 PF07646.10 ETO02603.1 - 9.3e-08 31.5 0.5 0.00067 19.3 0.2 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.20 ETO02603.1 - 4.8e-07 29.2 0.2 5.9e-05 22.5 0.1 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETO02603.1 - 2.8e-06 27.2 0.2 0.013 15.6 0.2 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 ETO02603.1 - 1.1e-05 25.0 0.1 0.0089 15.7 0.0 2.4 1 1 1 2 2 2 2 Galactose oxidase, central domain SEO_C PF14577.1 ETO02603.1 - 0.018 14.4 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Sieve element occlusion C-terminus Kelch_5 PF13854.1 ETO02603.1 - 0.033 14.1 0.0 0.41 10.6 0.1 2.1 2 0 0 2 2 2 0 Kelch motif KOG2701 PF09762.4 ETO02604.1 - 0.013 15.5 4.5 0.016 15.3 3.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein (DUF2037) NYD-SP28_assoc PF14775.1 ETO02604.1 - 0.05 13.3 1.5 0.086 12.5 1.1 1.6 1 1 0 1 1 1 0 Sperm tail C-terminal domain Imm39 PF15600.1 ETO02604.1 - 0.12 12.2 6.5 0.15 11.9 4.5 1.2 1 0 0 1 1 1 0 Immunity protein 39 ImmE5 PF11480.3 ETO02604.1 - 0.31 10.8 2.3 0.36 10.6 1.2 1.5 1 1 1 2 2 2 0 Colicin-E5 Imm protein DUF3810 PF12725.2 ETO02604.1 - 0.39 9.5 4.5 0.45 9.3 3.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF2951 PF11166.3 ETO02604.1 - 0.41 10.5 16.7 0.47 10.3 11.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Atg14 PF10186.4 ETO02604.1 - 0.6 8.9 11.7 0.61 8.9 8.1 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PaaSYMP PF14738.1 ETO02604.1 - 0.63 9.7 11.2 0.63 9.7 7.7 1.1 1 0 0 1 1 1 0 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 Bap31 PF05529.7 ETO02604.1 - 3.8 6.9 13.5 4.4 6.7 9.4 1.0 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like RNase_H2-Ydr279 PF09468.5 ETO02604.1 - 5.8 6.0 16.7 6.5 5.8 11.6 1.0 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF3944 PF13099.1 ETO02605.1 - 0.0084 15.5 4.0 0.05 13.1 0.1 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF3944) DUF2757 PF10955.3 ETO02605.1 - 0.012 15.7 2.5 0.95 9.6 0.0 3.5 2 1 0 3 3 3 0 Protein of unknown function (DUF2757) MA3 PF02847.12 ETO02605.1 - 0.098 12.3 2.4 0.23 11.1 0.2 2.6 3 1 0 3 3 3 0 MA3 domain Cys_rich_FGFR PF00839.12 ETO02605.1 - 0.11 12.3 2.3 6 6.8 0.0 3.4 3 0 0 3 3 3 0 Cysteine rich repeat MOR2-PAG1_C PF14225.1 ETO02605.1 - 0.19 11.4 2.5 2.2 7.9 0.1 2.5 1 1 1 3 3 3 0 Cell morphogenesis C-terminal Fe-S_assembly PF04384.8 ETO02606.1 - 1.9 8.9 4.6 0.46 10.8 0.5 2.1 2 0 0 2 2 2 0 Iron-sulphur cluster assembly Arm PF00514.18 ETO02607.1 - 0.0016 18.1 0.0 0.028 14.2 0.0 2.9 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat V-ATPase_H_C PF11698.3 ETO02607.1 - 0.023 14.6 0.4 0.16 11.9 0.0 2.6 2 1 0 2 2 2 0 V-ATPase subunit H Peptidase_M1 PF01433.15 ETO02609.1 - 4.8e-19 68.7 0.4 6.4e-19 68.2 0.3 1.1 1 0 0 1 1 1 1 Peptidase family M1 SRP72 PF08492.7 ETO02609.1 - 3.1 8.2 8.0 2.9 8.3 0.1 2.2 2 0 0 2 2 2 0 SRP72 RNA-binding domain Proteasom_Rpn13 PF04683.8 ETO02610.1 - 0.049 13.7 0.2 0.082 12.9 0.2 1.3 1 0 0 1 1 1 0 Proteasome complex subunit Rpn13 ubiquitin receptor TBX PF12598.3 ETO02611.1 - 0.0086 16.4 3.5 0.014 15.7 2.4 1.3 1 0 0 1 1 1 1 T-box transcription factor DUF1777 PF08648.7 ETO02611.1 - 0.086 12.5 10.3 0.12 12.1 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Proteasom_Rpn13 PF04683.8 ETO02611.1 - 0.1 12.6 0.2 0.25 11.4 0.2 1.6 1 0 0 1 1 1 0 Proteasome complex subunit Rpn13 ubiquitin receptor DUF2891 PF11199.3 ETO02613.1 - 0.15 10.6 2.1 0.15 10.5 1.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2891) DUF4268 PF14088.1 ETO02613.1 - 1.9 8.1 9.3 4.1 7.0 2.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4268) CDC45 PF02724.9 ETO02614.1 - 0.06 11.3 6.4 0.069 11.1 4.4 1.0 1 0 0 1 1 1 0 CDC45-like protein DHHW PF14286.1 ETO02614.1 - 0.23 10.7 8.3 0.29 10.4 5.7 1.0 1 0 0 1 1 1 0 DHHW protein ETRAMP PF09716.5 ETO02614.1 - 0.72 9.8 4.6 16 5.5 3.2 2.2 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF4407 PF14362.1 ETO02614.1 - 6 5.7 6.9 7.2 5.4 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2951 PF11166.3 ETO02614.1 - 7 6.5 10.4 16 5.4 7.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2951) RVT_1 PF00078.22 ETO02615.1 - 3.4e-07 29.8 0.0 4.4e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Kelch_1 PF01344.20 ETO02616.1 - 1.9e-07 30.4 0.1 4.5e-05 22.9 0.1 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.10 ETO02616.1 - 9.1e-07 28.4 0.4 0.00022 20.8 0.1 2.5 2 1 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 ETO02616.1 - 6.8e-06 25.7 0.1 0.0024 17.5 0.0 2.4 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO02616.1 - 6.8e-05 22.8 0.1 0.0082 16.2 0.1 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.1 ETO02616.1 - 0.0033 17.3 0.1 0.04 13.8 0.2 2.1 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO02616.1 - 0.066 13.4 0.0 0.86 9.8 0.0 2.5 3 0 0 3 3 3 0 Galactose oxidase, central domain 7TM_GPCR_Srx PF10328.4 ETO02616.1 - 0.14 11.2 1.9 1.7 7.6 0.0 2.1 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Peptidase_U57 PF05582.7 ETO02618.1 - 0.039 12.9 1.3 0.047 12.6 0.9 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Peptidase_C48 PF02902.14 ETO02619.1 - 8.4e-19 68.0 3.7 9.3e-19 67.9 2.6 1.0 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.8 ETO02619.1 - 0.0039 15.7 6.0 0.19 10.1 1.0 2.1 1 1 1 2 2 2 2 Vaccinia virus I7 processing peptidase Peptidase_C5 PF00770.13 ETO02619.1 - 0.45 10.0 3.0 2.5 7.6 2.1 1.9 1 1 0 1 1 1 0 Adenovirus endoprotease Cys_rich_KTR PF14205.1 ETO02620.1 - 0.0098 15.3 1.3 0.055 12.9 0.5 2.0 2 0 0 2 2 2 1 Cysteine-rich KTR ORF6C PF10552.4 ETO02620.1 - 0.048 13.3 0.6 0.058 13.1 0.4 1.2 1 0 0 1 1 1 0 ORF6C domain zf-C3HC4_2 PF13923.1 ETO02621.1 - 0.11 12.4 3.8 0.73 9.9 1.4 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO02621.1 - 3.9 7.2 7.3 16 5.2 1.1 2.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF4007 PF13182.1 ETO02622.1 - 0.0024 16.7 0.6 0.094 11.5 0.3 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF4007) APG5 PF04106.7 ETO02622.1 - 0.092 12.2 1.4 0.12 11.8 1.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg5 Toxin_54 PF15533.1 ETO02623.1 - 0.054 13.7 0.3 0.096 12.9 0.2 1.4 1 0 0 1 1 1 0 Putative toxin 54 PRESAN PF09687.5 ETO02625.1 - 0.0044 17.0 8.9 0.013 15.5 6.2 1.8 1 1 0 1 1 1 1 Plasmodium RESA N-terminal TMF_DNA_bd PF12329.3 ETO02625.1 - 0.005 16.6 9.6 0.012 15.3 6.6 1.7 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding Spc7 PF08317.6 ETO02625.1 - 0.0099 14.5 12.4 0.0084 14.8 7.8 1.5 1 1 0 1 1 1 1 Spc7 kinetochore protein AAA_13 PF13166.1 ETO02625.1 - 0.041 12.3 18.6 0.0065 14.9 10.1 1.5 1 1 0 2 2 2 0 AAA domain DUF641 PF04859.7 ETO02625.1 - 0.07 12.8 5.6 0.093 12.4 2.5 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Reo_sigmaC PF04582.7 ETO02625.1 - 0.074 12.2 0.3 0.089 11.9 0.2 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF3467 PF11950.3 ETO02625.1 - 0.13 12.3 0.9 0.81 9.7 0.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3467) Tropomyosin_1 PF12718.2 ETO02625.1 - 0.13 12.1 12.9 0.07 12.9 5.2 2.4 1 1 0 2 2 2 0 Tropomyosin like DUF3450 PF11932.3 ETO02625.1 - 0.21 10.8 5.7 0.29 10.3 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) IncA PF04156.9 ETO02625.1 - 0.28 10.7 8.1 0.27 10.7 4.9 1.4 1 1 0 1 1 1 0 IncA protein Laminin_II PF06009.7 ETO02625.1 - 0.41 10.3 10.7 0.38 10.4 6.4 1.6 1 1 0 1 1 1 0 Laminin Domain II NPV_P10 PF05531.7 ETO02625.1 - 2.7 8.2 13.1 13 6.1 8.3 2.3 2 1 0 2 2 1 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.17 ETO02625.1 - 3.8 7.5 12.7 1.2 9.2 6.1 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain SlyX PF04102.7 ETO02625.1 - 3.8 7.9 8.6 16 5.9 5.9 2.1 1 1 0 1 1 1 0 SlyX DUF1664 PF07889.7 ETO02625.1 - 5.5 6.7 8.9 1.4 8.7 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.6 ETO02625.1 - 5.6 6.9 9.2 11 5.9 6.0 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Innexin PF00876.13 ETO02627.1 - 0.046 12.8 0.4 0.058 12.4 0.3 1.0 1 0 0 1 1 1 0 Innexin NIR_SIR PF01077.17 ETO02628.1 - 0.11 11.9 0.1 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain DUF2545 PF10810.3 ETO02628.1 - 0.11 12.8 0.4 0.2 12.0 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2545) MKT1_N PF12247.3 ETO02628.1 - 0.12 12.7 0.1 0.3 11.4 0.0 1.6 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication NACHT PF05729.7 ETO02629.1 - 1.2e-18 67.2 0.0 2.9e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETO02629.1 - 0.00026 21.0 0.0 0.00076 19.5 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 ETO02629.1 - 0.00071 18.5 2.4 0.0099 14.7 1.7 2.8 1 1 0 1 1 1 1 NB-ARC domain Sigma54_activ_2 PF14532.1 ETO02629.1 - 0.012 15.6 0.1 0.89 9.5 0.1 2.6 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.1 ETO02629.1 - 0.032 14.3 0.1 0.11 12.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.14 ETO02629.1 - 0.039 13.1 0.1 0.039 13.1 0.0 2.8 2 1 2 4 4 4 0 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.16 ETO02629.1 - 0.056 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 ETO02629.1 - 0.057 13.7 0.0 0.057 13.7 0.0 2.9 2 1 1 3 3 3 0 AAA domain AAA_19 PF13245.1 ETO02629.1 - 0.058 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain DUF3722 PF12519.3 ETO02629.1 - 0.072 12.3 4.5 0.036 13.2 0.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3722) RRM_5 PF13893.1 ETO02630.1 - 0.11 12.3 0.1 0.97 9.3 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_S49_N PF08496.5 ETO02630.1 - 0.13 12.0 1.7 0.2 11.4 1.2 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FWWh PF14922.1 ETO02631.1 - 0.0049 16.3 2.0 0.0059 16.1 1.4 1.2 1 1 0 1 1 1 1 Protein of unknown function HTH_44 PF14641.1 ETO02631.1 - 0.14 12.1 2.0 0.57 10.1 0.0 2.3 1 1 2 3 3 3 0 Helix-turn-helix DNA-binding domain of SPT6 Sec20 PF03908.8 ETO02631.1 - 0.66 9.7 3.2 0.91 9.2 0.5 2.1 1 1 1 2 2 2 0 Sec20 NS3_envE PF02723.9 ETO02631.1 - 0.74 9.7 5.5 0.24 11.3 0.8 2.3 1 1 1 2 2 2 0 Non-structural protein NS3/Small envelope protein E Ank_4 PF13637.1 ETO02632.1 - 3.2e-06 27.4 2.4 1.3e-05 25.5 0.2 3.0 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO02632.1 - 5.2e-05 23.3 0.0 0.0002 21.4 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 ETO02632.1 - 0.00052 19.7 0.0 0.0029 17.3 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 ETO02632.1 - 0.00065 19.9 0.0 0.0019 18.4 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO02632.1 - 0.041 14.1 0.6 0.36 11.2 0.0 3.0 4 0 0 4 4 4 0 Ankyrin repeat CAP_GLY PF01302.20 ETO02633.1 - 0.0021 17.6 0.1 0.0027 17.3 0.1 1.4 1 1 0 1 1 1 1 CAP-Gly domain PBP1_TM PF14812.1 ETO02635.1 - 1.5 9.2 10.9 1.5 9.1 7.6 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tom22 PF04281.8 ETO02635.1 - 1.7 8.1 5.0 1.7 8.1 3.5 1.0 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Sigma70_ner PF04546.8 ETO02635.1 - 1.7 8.1 7.9 1.6 8.2 5.5 1.0 1 0 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.6 ETO02635.1 - 1.8 8.3 6.5 1.6 8.4 4.5 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_B PF00136.16 ETO02637.1 - 0.00058 18.7 0.1 0.00074 18.4 0.0 1.2 1 1 0 1 1 1 1 DNA polymerase family B Exo_endo_phos_2 PF14529.1 ETO02638.1 - 3.1e-10 39.6 0.1 7.9e-10 38.3 0.1 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 ETO02638.1 - 0.17 11.7 0.0 0.27 11.1 0.0 1.5 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Dala_Dala_lig_N PF01820.16 ETO02638.1 - 1 9.6 5.7 0.72 10.1 0.2 2.5 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus CDC37_N PF03234.9 ETO02638.1 - 8.4 6.6 16.3 0.25 11.6 3.9 2.6 3 0 0 3 3 3 0 Cdc37 N terminal kinase binding Exo_endo_phos_2 PF14529.1 ETO02639.1 - 1.1e-05 25.0 0.1 3.3e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase BSMAP PF12280.3 ETO02639.1 - 0.15 11.9 0.1 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 Brain specific membrane anchored protein XPG_I_2 PF12813.2 ETO02639.1 - 1.1 8.7 5.6 5 6.5 1.3 2.3 2 0 0 2 2 2 0 XPG domain containing DUF1796 PF08795.5 ETO02639.1 - 2.9 7.4 7.2 0.48 10.0 0.7 2.4 2 1 0 3 3 3 0 Putative papain-like cysteine peptidase (DUF1796) SPK PF04435.13 ETO02639.1 - 8.1 6.4 9.2 1.5 8.8 1.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF545) ARF7EP_C PF14949.1 ETO02640.1 - 0.042 14.2 4.9 0.05 14.0 3.4 1.3 1 0 0 1 1 1 0 ARF7 effector protein C-terminus TMF_DNA_bd PF12329.3 ETO02641.1 - 0.046 13.5 14.0 0.051 13.3 5.8 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Jnk-SapK_ap_N PF09744.4 ETO02641.1 - 0.079 12.9 10.2 0.083 12.8 7.0 1.0 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 ATG16 PF08614.6 ETO02641.1 - 1.2 8.8 11.3 1.5 8.6 7.8 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) HlyD_2 PF12700.2 ETO02641.1 - 3.1 6.8 8.7 3.4 6.7 6.0 1.0 1 0 0 1 1 1 0 HlyD family secretion protein BRE1 PF08647.6 ETO02641.1 - 3.5 7.6 11.2 3.5 7.6 3.6 2.1 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase IncA PF04156.9 ETO02641.1 - 5.1 6.6 11.0 5.4 6.5 7.6 1.1 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 ETO02641.1 - 5.6 6.5 15.1 0.67 9.4 5.1 2.1 1 1 1 2 2 2 0 Septum formation initiator TH1 PF04858.8 ETO02642.1 - 0.0072 14.5 1.2 0.12 10.5 0.0 2.0 2 0 0 2 2 2 2 TH1 protein IL34 PF15036.1 ETO02642.1 - 0.04 13.4 0.3 0.066 12.7 0.1 1.4 2 0 0 2 2 2 0 Interleukin 34 WD40 PF00400.27 ETO02644.1 - 2.9e-61 201.2 19.3 2.1e-10 40.0 0.4 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO02644.1 - 1.3e-10 40.0 4.2 0.0025 16.0 0.2 5.1 1 1 5 6 6 6 3 Nucleoporin Nup120/160 Reo_sigmaC PF04582.7 ETO02644.1 - 0.0099 15.0 1.0 0.016 14.3 0.7 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Macoilin PF09726.4 ETO02644.1 - 0.048 11.9 17.1 0.065 11.5 11.9 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF848 PF05852.6 ETO02644.1 - 0.12 12.2 18.0 0.17 11.6 11.8 1.8 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF641 PF04859.7 ETO02644.1 - 0.12 12.1 10.1 0.23 11.2 7.0 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) IncA PF04156.9 ETO02644.1 - 0.18 11.4 31.0 0.09 12.3 19.9 1.7 1 1 1 2 2 2 0 IncA protein DUF342 PF03961.8 ETO02644.1 - 0.19 10.0 15.5 0.29 9.4 10.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4404 PF14357.1 ETO02644.1 - 0.34 11.3 11.6 1 9.8 8.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) DUF3450 PF11932.3 ETO02644.1 - 0.43 9.8 13.4 0.78 8.9 9.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) GCD14 PF08704.5 ETO02644.1 - 0.67 9.4 6.0 1.3 8.4 4.1 1.5 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Allexi_40kDa PF05549.6 ETO02644.1 - 2.5 7.3 14.0 5.7 6.1 9.3 1.9 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF948 PF06103.6 ETO02644.1 - 2.7 7.9 6.7 6.8 6.6 4.6 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.7 ETO02644.1 - 8.9 6.1 16.2 0.21 11.3 4.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) LMBR1 PF04791.11 ETO02644.1 - 9.1 4.7 7.5 13 4.2 5.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein UCH PF00443.24 ETO02645.1 - 4.5e-06 25.9 3.1 0.00087 18.4 0.2 2.1 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO02645.1 - 0.017 14.5 2.4 0.024 14.0 0.4 1.7 1 1 1 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase PLA2_inh PF02988.10 ETO02646.1 - 0.56 10.6 5.6 0.31 11.5 0.8 2.6 2 1 1 3 3 3 0 Phospholipase A2 inhibitor FemAB PF02388.11 ETO02647.1 - 5.1 5.6 7.6 5.3 5.6 5.2 1.0 1 0 0 1 1 1 0 FemAB family DUF4407 PF14362.1 ETO02647.1 - 6.3 5.6 6.3 6.5 5.6 4.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1510 PF07423.6 ETO02647.1 - 8.7 5.6 11.7 10 5.4 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ycf1 PF05758.7 ETO02647.1 - 9.5 3.7 7.6 8.9 3.8 5.3 1.0 1 0 0 1 1 1 0 Ycf1 DUF29 PF01724.11 ETO02648.1 - 0.16 11.8 1.6 0.21 11.4 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF29 TPR_11 PF13414.1 ETO02649.1 - 2.1e-13 49.7 8.9 2.8e-09 36.4 1.4 2.3 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 ETO02649.1 - 2.4e-09 36.4 3.1 0.008 16.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO02649.1 - 5.4e-09 35.2 6.3 0.00051 19.5 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO02649.1 - 9.7e-07 28.1 7.7 0.059 13.1 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO02649.1 - 1.1e-06 28.3 7.8 0.0013 18.8 0.6 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO02649.1 - 4.3e-06 26.9 0.0 0.00045 20.4 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO02649.1 - 6.6e-06 26.1 5.8 9.8e-06 25.6 4.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETO02649.1 - 1.5e-05 25.1 1.2 2.8 8.5 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO02649.1 - 3.8e-05 23.1 0.1 3.7 7.5 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO02649.1 - 0.00028 20.7 6.2 3.1 7.8 0.0 3.0 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO02649.1 - 0.0061 17.1 0.0 0.43 11.3 0.0 2.7 1 1 2 3 3 3 1 Tetratricopeptide repeat zf-TRAF PF02176.13 ETO02650.1 - 2.8e-06 27.5 1.9 2.8e-06 27.5 1.3 2.5 3 0 0 3 3 3 1 TRAF-type zinc finger DUF1644 PF07800.7 ETO02650.1 - 1.1 9.1 7.6 23 4.8 1.9 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) zf-H2C2_5 PF13909.1 ETO02650.1 - 2.4 8.5 7.7 5.2 7.5 0.9 3.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain 7tm_1 PF00001.16 ETO02652.1 - 0.0026 16.9 0.2 0.0032 16.6 0.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2615 PF11027.3 ETO02652.1 - 0.011 15.6 3.2 1.4 8.8 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) Imm23 PF15593.1 ETO02652.1 - 0.023 14.9 0.8 0.028 14.6 0.6 1.1 1 0 0 1 1 1 0 Immunity protein 23 TMEM237 PF15383.1 ETO02652.1 - 0.081 12.0 0.2 0.091 11.8 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 237 COX4_pro_2 PF07835.7 ETO02652.1 - 0.096 12.6 0.8 0.096 12.6 0.6 2.1 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV Cytochrom_C_asm PF01578.15 ETO02652.1 - 0.8 9.2 3.7 1.4 8.4 0.6 1.9 1 1 1 2 2 2 0 Cytochrome C assembly protein Fer2_4 PF13510.1 ETO02654.1 - 2.1e-19 69.1 0.5 3.8e-19 68.2 0.3 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 ETO02654.1 - 7e-17 60.3 0.0 7e-17 60.3 0.0 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.22 ETO02654.1 - 4.1e-11 42.4 0.4 4.1e-11 42.4 0.3 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.1 ETO02654.1 - 0.031 14.6 1.5 0.097 13.1 1.1 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_19 PF06902.6 ETO02654.1 - 0.053 13.3 1.5 18 5.2 0.0 2.7 2 0 0 2 2 2 0 Divergent 4Fe-4S mono-cluster Fer4 PF00037.22 ETO02654.1 - 0.63 9.7 6.9 1.5 8.5 0.3 3.1 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_6 PF12837.2 ETO02654.1 - 6.5 6.7 9.9 0.27 11.1 0.8 3.1 3 0 0 3 3 3 0 4Fe-4S binding domain DUF4197 PF13852.1 ETO02658.1 - 0.011 15.3 0.7 0.016 14.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4197) Occludin_ELL PF07303.8 ETO02658.1 - 0.26 12.0 5.3 1.1 10.0 0.7 2.6 1 1 1 2 2 2 0 Occludin homology domain DASH_Duo1 PF08651.5 ETO02658.1 - 0.51 9.9 9.8 0.44 10.1 5.0 2.2 1 1 2 3 3 3 0 DASH complex subunit Duo1 Sec20 PF03908.8 ETO02658.1 - 1.9 8.2 8.4 6.2 6.6 5.6 2.0 1 1 0 1 1 1 0 Sec20 UPF0118 PF01594.11 ETO02658.1 - 3.9 6.3 5.3 5 6.0 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF20 UPF0697 PF15117.1 ETO02658.1 - 6.5 6.5 8.4 0.33 10.7 0.8 2.4 1 1 1 2 2 2 0 Uncharacterised protein family UPF0697 DUF1311 PF07007.7 ETO02658.1 - 6.9 6.8 7.5 20 5.3 3.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1311) Glyco_hydro_47 PF01532.15 ETO02661.1 - 1.2e-58 198.9 3.7 1.4e-58 198.6 2.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Ank_2 PF12796.2 ETO02663.1 - 1.5e-05 25.2 0.1 3.2e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO02663.1 - 2.7e-05 24.5 0.2 8e-05 23.0 0.2 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO02663.1 - 0.0017 18.3 0.4 4.3 7.8 0.1 3.5 2 1 0 2 2 2 2 Ankyrin repeat Ank PF00023.25 ETO02663.1 - 0.012 15.3 0.1 0.75 9.7 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.1 ETO02663.1 - 0.03 14.5 0.1 0.086 13.1 0.1 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) ubiquitin PF00240.18 ETO02664.1 - 3.5e-12 45.5 5.5 7.7e-06 25.2 0.5 5.0 3 2 0 3 3 3 2 Ubiquitin family UPF0565 PF10561.4 ETO02665.1 - 0.047 12.5 1.0 0.05 12.4 0.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Ribosomal_60s PF00428.14 ETO02665.1 - 0.14 12.5 6.7 0.18 12.1 4.6 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Sec62 PF03839.11 ETO02665.1 - 0.19 11.1 6.7 0.21 10.9 4.7 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Cytomega_UL84 PF06284.6 ETO02665.1 - 0.32 9.3 2.6 0.35 9.2 1.8 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Myc_N PF01056.13 ETO02665.1 - 0.5 9.4 4.8 0.55 9.3 3.3 1.1 1 0 0 1 1 1 0 Myc amino-terminal region GOLD_2 PF13897.1 ETO02665.1 - 4.3 7.5 6.5 9 6.5 4.5 1.7 1 1 0 1 1 1 0 Golgi-dynamics membrane-trafficking DUF1198 PF06711.6 ETO02666.1 - 0.022 14.5 0.2 3.8 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1198) TINF2_N PF14973.1 ETO02666.1 - 0.25 11.4 2.6 0.31 11.1 0.0 2.3 3 1 0 3 3 3 0 TERF1-interacting nuclear factor 2 N-terminus PrsW-protease PF13367.1 ETO02667.1 - 0.04 13.0 4.7 0.25 10.4 1.8 2.1 1 1 1 2 2 2 0 Protease prsW family Helicase_C PF00271.26 ETO02668.1 - 0.0016 18.2 0.1 0.0096 15.7 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF3891 PF13030.1 ETO02668.1 - 0.067 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3891) DUF3161 PF11362.3 ETO02669.1 - 0.095 12.6 0.1 0.22 11.4 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3161) Topoisom_bac PF01131.15 ETO02670.1 - 1.5e-31 109.6 0.0 1.7e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 DNA topoisomerase PAP_central PF04928.12 ETO02671.1 - 0.012 14.4 0.1 0.019 13.7 0.1 1.3 1 0 0 1 1 1 0 Poly(A) polymerase central domain DUF2491 PF10679.4 ETO02672.1 - 0.095 11.6 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) Nop52 PF05997.7 ETO02673.1 - 8e-42 143.1 1.2 5.5e-41 140.3 0.8 1.8 1 1 0 1 1 1 1 Nucleolar protein,Nop52 AAA PF00004.24 ETO02675.1 - 3.6e-05 23.9 1.1 0.0013 18.9 0.0 3.4 3 1 1 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETO02675.1 - 0.00016 21.4 0.0 0.52 10.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETO02675.1 - 0.02 15.0 0.0 0.52 10.4 0.0 3.3 2 1 0 2 2 2 0 AAA domain DUF440 PF04269.7 ETO02676.1 - 0.0014 18.6 0.5 0.0014 18.6 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF440 HTH_40 PF14493.1 ETO02677.1 - 0.25 11.5 3.8 0.58 10.4 0.1 2.9 2 1 1 3 3 3 0 Helix-turn-helix domain DUF1985 PF09331.6 ETO02678.1 - 0.0039 17.0 0.7 0.0057 16.4 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1985) FAM176 PF14851.1 ETO02678.1 - 0.012 15.3 0.4 0.022 14.4 0.3 1.4 1 0 0 1 1 1 0 FAM176 family WD40 PF00400.27 ETO02679.1 - 0.00088 19.0 0.5 0.0014 18.4 0.4 1.3 1 0 0 1 1 1 1 WD domain, G-beta repeat RVT_1 PF00078.22 ETO02680.1 - 2.4e-28 98.9 0.9 2.4e-28 98.9 0.6 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4247 PF14042.1 ETO02680.1 - 0.0086 16.0 0.5 1.4 8.9 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4247) DHC PF09626.5 ETO02680.1 - 0.15 12.7 2.8 0.13 12.9 0.3 2.1 2 0 0 2 2 2 0 Dihaem cytochrome c Imm45 PF15603.1 ETO02680.1 - 9.2 6.4 13.8 1.7 8.8 0.2 4.6 4 1 0 4 4 4 0 Immunity protein 45 Band_3_cyto PF07565.8 ETO02682.1 - 0.057 12.9 0.6 0.066 12.7 0.4 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain zf-MIZ PF02891.15 ETO02682.1 - 0.095 12.2 0.5 0.095 12.2 0.3 2.7 4 0 0 4 4 4 0 MIZ/SP-RING zinc finger zf-C3HC4_2 PF13923.1 ETO02682.1 - 1.1 9.3 7.4 0.36 10.9 0.9 3.0 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 ETO02682.1 - 1.3 8.9 6.4 1.4 8.8 1.1 3.3 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Cse1 PF08506.5 ETO02683.1 - 0.0029 16.2 7.7 0.34 9.4 0.3 3.5 2 2 1 3 3 3 3 Cse1 DUF3944 PF13099.1 ETO02683.1 - 0.068 12.6 2.4 1.2 8.7 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3944) DUF155 PF02582.9 ETO02683.1 - 0.13 12.1 2.9 0.76 9.6 1.9 2.1 1 1 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 Ank_2 PF12796.2 ETO02683.1 - 0.52 10.6 2.7 5.4 7.4 1.8 2.7 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Gastrin PF00918.12 ETO02684.1 - 4 8.2 8.4 5.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Gastrin/cholecystokinin family Zip PF02535.17 ETO02684.1 - 9.8 5.0 7.1 1.9 7.4 1.4 1.9 1 1 1 2 2 2 0 ZIP Zinc transporter Kelch_5 PF13854.1 ETO02685.1 - 0.064 13.2 0.0 5.7 6.9 0.0 2.2 2 0 0 2 2 2 0 Kelch motif GF_recep_IV PF14843.1 ETO02685.1 - 0.082 12.5 0.3 0.088 12.4 0.2 1.1 1 0 0 1 1 1 0 Growth factor receptor domain IV Kelch_6 PF13964.1 ETO02685.1 - 0.095 12.9 0.0 1.3 9.3 0.0 2.1 2 0 0 2 2 2 0 Kelch motif Kelch_2 PF07646.10 ETO02685.1 - 0.15 11.8 0.2 0.46 10.3 0.1 1.9 1 1 0 1 1 1 0 Kelch motif WD40 PF00400.27 ETO02686.1 - 2.9e-13 49.1 6.6 4.2e-12 45.4 0.3 2.8 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO02686.1 - 0.089 10.9 0.1 0.091 10.8 0.1 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 FlgM PF04316.8 ETO02687.1 - 0.032 14.1 1.6 0.051 13.5 1.1 1.3 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM WD40 PF00400.27 ETO02688.1 - 3.1e-31 106.1 5.3 5.4e-10 38.7 0.0 4.7 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO02688.1 - 8.7e-06 24.1 1.8 0.21 9.6 0.0 3.7 1 1 3 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO02688.1 - 2.1e-05 24.3 0.1 0.14 11.8 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 ETO02688.1 - 0.00052 18.8 8.0 0.3 9.7 2.1 3.6 1 1 2 3 3 3 2 Nup133 N terminal like Hira PF07569.6 ETO02688.1 - 0.0016 17.7 0.8 6 6.0 0.0 3.9 1 1 4 5 5 5 1 TUP1-like enhancer of split Cytochrom_D1 PF02239.11 ETO02688.1 - 0.0016 16.8 0.1 0.012 13.9 0.0 2.1 1 1 1 2 2 2 1 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO02688.1 - 0.0067 15.9 0.1 0.06 12.7 0.1 2.7 1 1 0 1 1 1 1 PQQ-like domain DPPIV_N PF00930.16 ETO02688.1 - 0.047 12.2 0.1 6 5.3 0.0 2.6 1 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Str_synth PF03088.11 ETO02688.1 - 0.062 13.3 0.0 1.5 8.8 0.0 2.7 1 1 2 3 3 3 0 Strictosidine synthase SGL PF08450.7 ETO02688.1 - 0.11 11.8 0.0 1.2 8.4 0.0 2.2 1 1 1 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region DUF2981 PF11200.3 ETO02690.1 - 0.0096 15.0 2.7 0.011 14.9 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2981) TFIIA PF03153.8 ETO02690.1 - 3.3 7.5 9.6 4.1 7.1 6.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop PF01798.13 ETO02691.1 - 6.6e-37 126.1 0.2 7.9e-37 125.8 0.2 1.1 1 0 0 1 1 1 1 Putative snoRNA binding domain WD40 PF00400.27 ETO02692.1 - 2.5e-06 27.1 0.6 2.5e-06 27.1 0.4 2.1 2 1 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO02692.1 - 0.081 11.0 0.0 0.12 10.4 0.0 1.4 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Sina PF03145.11 ETO02693.1 - 0.0011 18.6 0.2 0.0012 18.5 0.1 1.1 1 0 0 1 1 1 1 Seven in absentia protein family DUF3919 PF13057.1 ETO02693.1 - 0.059 12.8 3.8 0.064 12.7 2.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) DUF1680 PF07944.7 ETO02694.1 - 1.3e-08 33.6 0.6 7.2e-07 27.8 0.1 2.1 2 0 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) DUF913 PF06025.7 ETO02695.1 - 5.6 5.6 12.5 7.8 5.1 8.6 1.3 1 1 0 1 1 1 0 Domain of Unknown Function (DUF913) Cwf_Cwc_15 PF04889.7 ETO02695.1 - 6.4 6.4 35.9 7.2 6.2 24.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Daxx PF03344.10 ETO02695.1 - 7.9 4.8 29.6 8.5 4.7 20.5 1.1 1 0 0 1 1 1 0 Daxx Family mRNA_cap_C PF03919.10 ETO02696.1 - 0.038 14.3 0.2 0.096 13.0 0.1 1.8 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain IcmL PF11393.3 ETO02696.1 - 0.069 13.0 0.3 0.15 11.9 0.2 1.6 1 0 0 1 1 1 0 Macrophage killing protein with similarity to conjugation protein DUF1624 PF07786.7 ETO02697.1 - 0.069 12.4 1.8 0.82 8.9 0.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1624) PRD PF00874.15 ETO02697.1 - 0.16 12.1 1.2 19 5.4 0.0 2.4 2 0 0 2 2 2 0 PRD domain WD40 PF00400.27 ETO02698.1 - 2.2e-22 78.0 7.9 8.4e-07 28.6 0.0 5.9 5 1 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 ETO02698.1 - 0.0094 15.6 0.1 0.039 13.6 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO02698.1 - 0.025 12.7 1.2 0.78 7.7 0.1 2.4 1 1 0 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO02698.1 - 0.028 13.1 1.4 0.23 10.1 0.2 2.4 1 1 2 3 3 3 0 Nup133 N terminal like RVT_thumb PF06817.9 ETO02698.1 - 0.12 11.9 1.1 20 4.8 0.0 3.1 4 0 0 4 4 4 0 Reverse transcriptase thumb domain ATP-synt_S1 PF05827.7 ETO02699.1 - 0.5 9.6 10.3 0.7 9.1 7.1 1.3 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) FlaC_arch PF05377.6 ETO02699.1 - 0.91 9.4 19.5 0.17 11.7 3.0 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.7 ETO02699.1 - 1 9.2 20.9 3 7.6 6.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Paralemmin PF03285.10 ETO02699.1 - 1.4 8.3 18.5 0.16 11.3 7.0 2.3 1 1 1 2 2 2 0 Paralemmin DUF1494 PF07379.6 ETO02699.1 - 3.2 7.6 9.5 0.1 12.4 0.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1494) DUF1359 PF07097.6 ETO02699.1 - 6.5 6.8 22.8 0.31 11.1 3.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1359) S_layer_C PF05124.7 ETO02701.1 - 0.75 9.3 3.5 0.33 10.5 0.7 1.6 2 0 0 2 2 2 0 S-layer like family, C-terminal region Meiotic_rec114 PF03525.9 ETO02702.1 - 0.0076 14.7 1.8 0.008 14.7 1.3 1.0 1 0 0 1 1 1 1 Meiotic recombination protein rec114 DUF2777 PF10949.3 ETO02703.1 - 0.0086 15.7 0.8 0.011 15.4 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2777) Spc7 PF08317.6 ETO02704.1 - 0.0017 17.1 7.0 0.0017 17.1 4.9 2.5 2 1 0 2 2 2 1 Spc7 kinetochore protein Baculo_PEP_C PF04513.7 ETO02704.1 - 0.002 17.9 3.7 0.006 16.4 0.2 2.5 2 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus WXG100 PF06013.7 ETO02704.1 - 0.0087 16.0 4.1 6.7 6.7 0.1 4.4 5 1 0 5 5 4 1 Proteins of 100 residues with WXG AAA_13 PF13166.1 ETO02704.1 - 0.02 13.4 29.9 0.0043 15.5 6.4 2.2 1 1 1 2 2 2 0 AAA domain NPV_P10 PF05531.7 ETO02704.1 - 0.066 13.4 4.1 0.14 12.4 0.1 3.1 2 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein HlyD PF00529.15 ETO02704.1 - 0.11 11.7 2.7 0.18 11.0 1.9 1.4 1 0 0 1 1 1 0 HlyD family secretion protein KfrA_N PF11740.3 ETO02704.1 - 0.14 12.6 2.1 7.3 7.0 0.1 3.2 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term DUF4094 PF13334.1 ETO02704.1 - 0.33 11.3 7.3 4 7.8 0.3 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) DUF1664 PF07889.7 ETO02704.1 - 0.54 10.0 9.5 1.6 8.5 0.3 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF1939 PF09154.5 ETO02704.1 - 0.57 10.1 3.6 1 9.3 1.6 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1939) COG2 PF06148.6 ETO02704.1 - 0.71 9.7 20.5 0.98 9.2 0.2 4.5 2 2 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Med9 PF07544.8 ETO02704.1 - 1 9.1 0.0 1 9.1 0.0 4.1 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 IncA PF04156.9 ETO02704.1 - 1.6 8.3 25.7 8.4 5.9 5.2 3.4 2 1 0 2 2 2 0 IncA protein DUF883 PF05957.8 ETO02704.1 - 1.8 9.0 11.3 0.41 11.0 0.2 3.6 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) ApoO PF09769.4 ETO02704.1 - 2.3 7.9 11.4 14 5.3 0.0 3.8 2 1 2 4 4 4 0 Apolipoprotein O Laminin_II PF06009.7 ETO02704.1 - 3.1 7.5 16.0 0.36 10.5 0.8 3.9 2 2 2 4 4 4 0 Laminin Domain II ubiquitin PF00240.18 ETO02706.1 - 2.9e-21 74.6 0.2 1.8e-20 72.0 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 ETO02706.1 - 1.3e-11 43.9 0.0 4.5e-11 42.2 0.0 2.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Hint PF01079.15 ETO02706.1 - 7.2e-10 38.4 0.0 1.2e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Hint module PT-HINT PF07591.6 ETO02706.1 - 2.4e-05 24.2 0.5 7.5e-05 22.6 0.2 1.8 2 0 0 2 2 2 1 Pretoxin HINT domain AXH PF08517.7 ETO02706.1 - 4.9e-05 23.4 0.1 0.00023 21.2 0.0 2.2 2 0 0 2 2 2 1 Ataxin-1 and HBP1 module (AXH) Hom_end_hint PF05203.11 ETO02706.1 - 0.0006 19.6 0.4 0.0017 18.1 0.0 1.9 2 0 0 2 2 2 1 Hom_end-associated Hint DUF2407 PF10302.4 ETO02706.1 - 0.073 13.2 0.1 0.21 11.8 0.0 1.9 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain TPR_12 PF13424.1 ETO02707.1 - 1.8e-76 252.0 0.3 2e-28 98.1 0.0 2.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO02707.1 - 1.7e-38 129.4 0.0 6.5e-11 41.7 0.0 4.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO02707.1 - 8.9e-38 127.7 10.7 2.4e-16 59.1 0.2 3.0 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETO02707.1 - 2.7e-27 93.1 12.9 1e-08 34.4 0.2 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO02707.1 - 9.4e-27 90.6 0.3 6.8e-08 31.7 0.0 3.5 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO02707.1 - 1.7e-20 71.1 6.1 3e-06 26.7 0.1 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO02707.1 - 4e-19 66.8 16.2 6.1e-07 28.7 0.4 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO02707.1 - 5.5e-16 57.3 0.3 0.00058 19.8 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO02707.1 - 4.6e-12 46.2 0.0 0.00018 22.0 0.0 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO02707.1 - 1e-07 31.9 0.0 0.44 11.3 0.0 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat MIT PF04212.13 ETO02707.1 - 1.3e-06 28.1 5.9 0.042 13.7 0.1 3.2 3 0 0 3 3 3 3 MIT (microtubule interacting and transport) domain PPR PF01535.15 ETO02707.1 - 1.8e-06 27.5 3.6 0.6 10.2 0.1 3.2 3 0 0 3 3 3 3 PPR repeat TPR_3 PF07720.7 ETO02707.1 - 2.4e-06 27.2 5.1 0.22 11.3 0.1 3.6 4 0 0 4 4 3 2 Tetratricopeptide repeat Sel1 PF08238.7 ETO02707.1 - 7.9e-06 26.3 0.3 0.58 10.8 0.0 3.8 4 0 0 4 4 3 1 Sel1 repeat TPR_19 PF14559.1 ETO02707.1 - 3.1e-05 24.2 0.0 0.0097 16.2 0.0 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO02707.1 - 5.1e-05 23.3 0.9 0.01 15.9 0.1 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.1 ETO02707.1 - 0.00014 21.0 0.2 0.00033 19.8 0.1 1.5 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.1 ETO02707.1 - 0.00027 21.2 0.2 7.8 7.2 0.0 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF627 PF04781.7 ETO02707.1 - 0.00082 18.9 0.5 3.4 7.3 0.0 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF627) SHNi-TPR PF10516.4 ETO02707.1 - 0.0056 15.9 0.0 4.7 6.5 0.0 3.3 3 0 0 3 3 3 1 SHNi-TPR Fis1_TPR_C PF14853.1 ETO02707.1 - 0.32 10.9 4.9 13 5.7 0.2 3.3 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat FATC PF02260.15 ETO02707.1 - 0.36 10.3 1.4 23 4.5 0.0 2.6 3 0 0 3 3 3 0 FATC domain Bombolitin PF08096.6 ETO02707.1 - 0.53 10.4 0.0 0.53 10.4 0.0 2.6 4 0 0 4 4 2 0 Bombolitin family ATP-synt_E_2 PF08112.6 ETO02707.1 - 0.88 9.6 3.5 43 4.2 0.1 3.2 3 0 0 3 3 3 0 ATP synthase epsilon subunit DUF972 PF06156.8 ETO02708.1 - 0.00058 20.1 6.7 0.00058 20.1 4.6 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF972) HALZ PF02183.13 ETO02708.1 - 0.02 14.5 3.9 0.052 13.2 2.7 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper ADIP PF11559.3 ETO02708.1 - 0.041 13.7 12.9 0.052 13.4 8.9 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Peptidase_M17_N PF02789.12 ETO02708.1 - 0.097 12.4 0.2 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain Rootletin PF15035.1 ETO02708.1 - 0.23 11.4 10.7 0.54 10.2 7.0 1.8 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF384 PF04064.8 ETO02708.1 - 0.29 10.7 2.7 1.5 8.4 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF384) IncA PF04156.9 ETO02708.1 - 0.31 10.6 8.8 0.37 10.3 6.1 1.1 1 0 0 1 1 1 0 IncA protein DUF1798 PF08807.5 ETO02708.1 - 0.51 10.0 5.2 4.7 6.9 0.2 2.5 2 1 0 2 2 2 0 Bacterial domain of unknown function (DUF1798) zf-ZPR1 PF03367.8 ETO02708.1 - 0.84 8.7 4.1 1.3 8.1 2.8 1.5 1 1 0 1 1 1 0 ZPR1 zinc-finger domain DUF904 PF06005.7 ETO02708.1 - 0.93 9.8 14.9 2.8 8.3 9.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF904) ubiquitin PF00240.18 ETO02709.1 - 4.6e-102 333.4 13.3 9.7e-34 114.6 0.4 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.3 ETO02709.1 - 2e-60 200.4 12.1 2.5e-20 71.9 0.4 3.1 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 ETO02709.1 - 5.1e-20 71.5 5.2 3.4e-05 24.0 0.1 4.5 3 3 0 3 3 3 3 Ubiquitin-like domain Telomere_Sde2 PF13019.1 ETO02709.1 - 1.5e-13 50.7 0.1 0.0024 17.5 0.0 3.2 3 0 0 3 3 3 3 Telomere stability and silencing Rad60-SLD_2 PF13881.1 ETO02709.1 - 3.7e-12 46.1 1.7 0.021 14.6 0.0 3.9 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 ETO02709.1 - 2e-10 40.6 0.6 0.1 12.7 0.0 3.3 1 1 1 3 3 3 3 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 ETO02709.1 - 3e-08 33.4 2.8 0.17 11.8 0.0 3.2 3 0 0 3 3 3 3 GLUT4 regulating protein TUG DUF2870 PF11069.3 ETO02709.1 - 4e-08 33.2 0.1 0.99 9.4 0.0 4.2 3 3 1 4 4 4 3 Protein of unknown function (DUF2870) USP7_C2 PF14533.1 ETO02709.1 - 1.3e-06 28.0 1.7 0.53 9.6 0.1 3.1 3 0 0 3 3 3 3 Ubiquitin-specific protease C-terminal eRF1_1 PF03463.10 ETO02709.1 - 8.4e-06 25.3 1.4 0.95 9.0 0.0 4.2 1 1 3 4 4 4 2 eRF1 domain 1 FlgD_ig PF13860.1 ETO02709.1 - 0.00013 21.6 1.3 6.9 6.4 0.0 3.4 3 0 0 3 3 3 0 FlgD Ig-like domain PI3K_rbd PF00794.13 ETO02709.1 - 0.00015 21.6 3.6 2.7 7.9 0.0 3.4 3 0 0 3 3 3 2 PI3-kinase family, ras-binding domain GABP-alpha PF11620.3 ETO02709.1 - 0.00045 20.1 2.1 5.6 7.0 0.0 3.1 3 0 0 3 3 3 1 GA-binding protein alpha chain IGR PF09597.5 ETO02709.1 - 0.0025 17.6 0.0 30 4.5 0.0 3.4 3 0 0 3 3 3 0 IGR protein motif FERM_N PF09379.5 ETO02709.1 - 0.0056 16.6 5.7 14 5.7 0.1 4.7 3 3 0 3 3 3 0 FERM N-terminal domain DUF3379 PF11859.3 ETO02709.1 - 0.019 14.1 0.5 6 5.9 0.0 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF3379) CTDII PF01556.13 ETO02709.1 - 0.021 14.7 10.0 2.9 7.8 0.3 3.2 1 1 2 3 3 3 0 DnaJ C terminal domain DUF3435 PF11917.3 ETO02709.1 - 0.059 12.0 0.2 25 3.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3435) DUF1396 PF07161.8 ETO02709.1 - 0.082 12.5 0.8 6.6 6.3 0.0 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF1396) Big_3_3 PF13750.1 ETO02709.1 - 0.13 11.7 0.3 8.7 5.7 0.0 2.9 1 1 1 2 2 2 0 Bacterial Ig-like domain (group 3) Plexin_cytopl PF08337.7 ETO02709.1 - 0.41 8.8 9.5 4.8 5.3 0.2 4.3 4 2 0 4 4 4 0 Plexin cytoplasmic RasGAP domain PI3K_p85B PF02192.11 ETO02709.1 - 0.47 9.9 2.7 77 2.8 0.0 3.3 3 0 0 3 3 3 0 PI3-kinase family, p85-binding domain LMBR1 PF04791.11 ETO02710.1 - 0.22 10.0 3.6 0.089 11.3 0.5 1.6 2 0 0 2 2 2 0 LMBR1-like membrane protein Spt20 PF12090.3 ETO02710.1 - 1.9 7.8 11.2 5.7 6.2 7.8 1.8 1 1 0 1 1 1 0 Spt20 family RP-C_C PF11800.3 ETO02710.1 - 2.2 7.9 5.3 0.68 9.5 1.4 1.7 2 0 0 2 2 2 0 Replication protein C C-terminal region IncA PF04156.9 ETO02710.1 - 3.6 7.1 9.9 0.21 11.1 2.6 1.9 2 0 0 2 2 2 0 IncA protein WD40 PF00400.27 ETO02713.1 - 1.3e-50 167.5 16.6 1.3e-10 40.7 0.5 6.8 6 1 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO02713.1 - 9.1e-10 37.2 2.6 0.00039 18.7 0.1 4.0 1 1 1 4 4 4 4 Nucleoporin Nup120/160 Cyclin_C PF02984.14 ETO02714.1 - 0.045 13.6 0.0 0.064 13.1 0.0 1.2 1 0 0 1 1 1 0 Cyclin, C-terminal domain ELM2 PF01448.19 ETO02715.1 - 0.00055 20.5 0.0 0.0014 19.2 0.0 1.7 1 0 0 1 1 1 1 ELM2 domain UPF0300 PF08594.5 ETO02715.1 - 0.024 13.5 0.1 0.031 13.2 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0300) DUF4326 PF14216.1 ETO02717.1 - 0.017 15.6 0.6 0.032 14.8 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4326) PLU-1 PF08429.6 ETO02717.1 - 0.069 12.0 11.1 0.022 13.6 3.3 1.9 1 1 1 2 2 2 0 PLU-1-like protein DUF3213 PF11491.3 ETO02717.1 - 0.18 11.6 3.2 0.12 12.2 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3213) DivIC PF04977.10 ETO02717.1 - 0.22 11.0 0.3 0.22 11.0 0.2 3.3 1 1 2 4 4 4 0 Septum formation initiator ADIP PF11559.3 ETO02717.1 - 0.42 10.5 17.3 0.039 13.8 6.5 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Corona_S2 PF01601.11 ETO02717.1 - 0.64 8.0 8.1 0.68 7.9 5.6 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Kinesin-relat_1 PF12711.2 ETO02717.1 - 0.89 9.9 8.2 0.11 12.8 1.9 2.0 1 1 1 2 2 2 0 Kinesin motor zf-C4H2 PF10146.4 ETO02717.1 - 1.8 8.5 9.7 1.3 9.0 5.8 1.4 1 1 0 1 1 1 0 Zinc finger-containing protein Adaptin_binding PF10199.4 ETO02717.1 - 2.3 8.5 8.2 3 8.1 5.7 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Fib_alpha PF08702.5 ETO02717.1 - 2.5 8.2 14.2 1.3 9.0 8.5 1.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family IncA PF04156.9 ETO02717.1 - 7.5 6.0 9.1 11 5.6 6.3 1.2 1 0 0 1 1 1 0 IncA protein SlyX PF04102.7 ETO02717.1 - 9.9 6.6 8.5 1.1 9.7 1.8 2.2 2 1 1 3 3 3 0 SlyX Tctex-1 PF03645.8 ETO02718.1 - 0.36 10.6 3.5 1.1 9.1 2.4 1.9 1 1 0 1 1 1 0 Tctex-1 family Nop14 PF04147.7 ETO02719.1 - 0.00048 18.2 9.3 0.00048 18.2 6.4 1.1 1 0 0 1 1 1 1 Nop14-like family DUF809 PF05663.6 ETO02719.1 - 0.0022 17.9 0.4 0.0031 17.4 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF809) BSP_II PF05432.6 ETO02719.1 - 0.01 15.1 10.4 0.013 14.8 7.2 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Paf1 PF03985.8 ETO02719.1 - 0.016 13.9 9.1 0.018 13.7 6.3 1.2 1 0 0 1 1 1 0 Paf1 Ycf1 PF05758.7 ETO02719.1 - 0.022 12.5 4.6 0.021 12.5 3.2 1.1 1 0 0 1 1 1 0 Ycf1 TRAP_alpha PF03896.11 ETO02719.1 - 0.15 11.0 7.9 0.21 10.5 5.5 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit TFIIF_alpha PF05793.7 ETO02719.1 - 0.24 9.7 22.2 0.3 9.4 15.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1510 PF07423.6 ETO02719.1 - 0.38 10.1 12.1 0.55 9.5 8.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 ETO02719.1 - 0.64 7.9 11.9 0.8 7.6 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid PF03115.9 ETO02719.1 - 0.75 7.9 2.8 0.7 8.0 2.0 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF4637 PF15470.1 ETO02719.1 - 1.3 8.6 9.6 1.9 8.0 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CENP-T PF15511.1 ETO02719.1 - 1.9 7.6 10.3 2.5 7.2 7.1 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF2457 PF10446.4 ETO02719.1 - 4.5 5.8 16.6 6 5.4 11.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 ETO02719.1 - 5.2 5.4 18.7 7.4 4.9 13.0 1.2 1 0 0 1 1 1 0 Daxx Family Orbi_VP6 PF01516.11 ETO02719.1 - 8.1 5.4 13.2 11 5.0 9.1 1.1 1 0 0 1 1 1 0 Orbivirus helicase VP6 Med24_N PF11277.3 ETO02720.1 - 0.016 12.7 7.7 0.019 12.5 5.4 1.0 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal PA26 PF04636.8 ETO02720.1 - 0.63 8.6 7.4 0.67 8.5 5.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4200 PF13863.1 ETO02720.1 - 0.92 9.4 27.2 0.44 10.5 3.7 3.0 1 1 1 3 3 3 0 Domain of unknown function (DUF4200) Seryl_tRNA_N PF02403.17 ETO02720.1 - 1.3 9.0 28.6 0.8 9.7 14.5 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4239 PF14023.1 ETO02720.1 - 2.1 7.6 4.5 3.5 6.9 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) TMF_DNA_bd PF12329.3 ETO02720.1 - 2.6 7.8 39.0 0.7 9.7 7.9 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding WEMBL PF05701.6 ETO02720.1 - 3.2 6.1 25.0 3.8 5.8 17.3 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Allexi_40kDa PF05549.6 ETO02720.1 - 3.4 6.9 10.6 4.2 6.5 7.3 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF2524 PF10732.4 ETO02720.1 - 3.4 7.8 14.9 0.17 12.0 4.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2524) zf-C4H2 PF10146.4 ETO02720.1 - 3.7 7.5 19.8 7.2 6.5 13.7 1.6 1 1 0 1 1 1 0 Zinc finger-containing protein RasGAP_C PF03836.10 ETO02720.1 - 3.8 7.2 23.5 1.1 8.9 10.9 2.1 1 1 1 2 2 2 0 RasGAP C-terminus MAD PF05557.8 ETO02720.1 - 4.5 5.2 30.8 5.2 5.0 21.3 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein Mnd1 PF03962.10 ETO02720.1 - 4.9 6.7 24.3 6 6.4 15.9 1.6 1 1 1 2 2 2 0 Mnd1 family Exonuc_VII_L PF02601.10 ETO02720.1 - 5.7 6.0 14.6 6.7 5.8 10.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4175 PF13779.1 ETO02720.1 - 8.4 3.9 11.8 11 3.5 8.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CALCOCO1 PF07888.6 ETO02720.1 - 9.3 4.4 19.4 10 4.2 13.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF913 PF06025.7 ETO02721.1 - 0.004 15.9 1.7 0.0071 15.1 0.0 2.2 3 0 0 3 3 3 1 Domain of Unknown Function (DUF913) Pilt PF15453.1 ETO02722.1 - 0.3 10.7 7.7 0.35 10.5 5.3 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions SAPS PF04499.10 ETO02722.1 - 2.1 6.9 15.0 2.3 6.7 10.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Utp14 PF04615.8 ETO02722.1 - 2.9 5.9 23.9 3.6 5.6 16.6 1.1 1 0 0 1 1 1 0 Utp14 protein DUF605 PF04652.11 ETO02722.1 - 3.3 7.0 19.7 3.6 6.8 13.6 1.0 1 0 0 1 1 1 0 Vta1 like TFIIF_alpha PF05793.7 ETO02722.1 - 4.3 5.5 29.2 5 5.3 20.2 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Daxx PF03344.10 ETO02722.1 - 4.6 5.6 31.5 6.3 5.1 21.9 1.2 1 0 0 1 1 1 0 Daxx Family Hid1 PF12722.2 ETO02722.1 - 9.6 3.7 18.2 11 3.5 12.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Cullin_binding PF03556.10 ETO02725.1 - 0.043 13.9 0.8 0.066 13.3 0.1 1.6 2 0 0 2 2 2 0 Cullin binding 7tm_1 PF00001.16 ETO02727.1 - 0.0023 17.1 0.1 0.0028 16.8 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2681 PF10883.3 ETO02727.1 - 0.056 13.6 1.1 0.078 13.1 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF4094 PF13334.1 ETO02727.1 - 0.064 13.6 0.0 0.079 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Tetraspannin PF00335.15 ETO02727.1 - 0.084 12.1 0.0 0.092 12.0 0.0 1.1 1 0 0 1 1 1 0 Tetraspanin family PEX11 PF05648.9 ETO02727.1 - 0.085 12.1 0.9 0.1 11.8 0.6 1.0 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) YMF19 PF02326.10 ETO02727.1 - 0.32 11.5 4.9 0.45 11.1 3.4 1.3 1 1 0 1 1 1 0 Plant ATP synthase F0 ETRAMP PF09716.5 ETO02727.1 - 0.38 10.7 5.6 0.84 9.6 3.9 1.6 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Clathrin_lg_ch PF01086.12 ETO02728.1 - 0.011 15.7 2.3 0.011 15.7 1.6 1.6 2 0 0 2 2 2 0 Clathrin light chain zf-CCHC_4 PF14392.1 ETO02728.1 - 0.17 11.5 19.6 0.23 11.1 2.6 3.5 2 2 1 3 3 3 0 Zinc knuckle CBM_21 PF03370.8 ETO02729.1 - 0.071 13.0 2.1 0.14 12.1 1.5 1.5 1 0 0 1 1 1 0 Putative phosphatase regulatory subunit DUF2457 PF10446.4 ETO02730.1 - 8 5.0 24.2 7.6 5.1 16.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DDOST_48kD PF03345.9 ETO02732.1 - 0.025 13.1 1.2 0.029 12.9 0.8 1.0 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta Endotoxin_N PF03945.9 ETO02732.1 - 0.065 12.6 1.9 0.076 12.3 1.3 1.2 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain PLA2_B PF01735.13 ETO02733.1 - 0.083 11.0 0.1 0.091 10.9 0.1 1.1 1 0 0 1 1 1 0 Lysophospholipase catalytic domain TF_AP-2 PF03299.9 ETO02734.1 - 0.047 13.2 3.4 0.058 12.9 2.3 1.2 1 0 0 1 1 1 0 Transcription factor AP-2 CCDC144C PF14915.1 ETO02734.1 - 0.058 12.3 19.1 0.026 13.4 5.2 2.1 1 1 0 2 2 2 0 CCDC144C protein coiled-coil region LRS4 PF10422.4 ETO02734.1 - 0.31 10.3 15.3 0.35 10.1 10.6 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 DUF3373 PF11853.3 ETO02734.1 - 1.9 6.8 9.4 2.3 6.6 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) WD40 PF00400.27 ETO02735.1 - 6.3e-120 387.2 39.3 2.5e-13 49.3 0.2 12.3 11 1 1 12 12 12 11 WD domain, G-beta repeat NACHT PF05729.7 ETO02735.1 - 3.1e-11 43.2 0.0 5.4e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO02735.1 - 3.6e-05 24.0 4.8 8.4e-05 22.8 0.0 3.1 2 1 1 3 3 3 1 AAA domain DUF1258 PF06869.7 ETO02735.1 - 0.00011 21.4 5.1 5.9 5.8 0.2 5.6 2 2 2 5 5 5 3 Protein of unknown function (DUF1258) AAA_22 PF13401.1 ETO02735.1 - 0.00027 21.0 0.0 0.00081 19.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO02735.1 - 0.0009 20.0 0.1 0.0085 16.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain TolB_N PF04052.8 ETO02735.1 - 0.0017 18.4 3.1 3.1 7.9 0.0 5.7 7 1 1 8 8 8 1 TolB amino-terminal domain ATP_bind_2 PF03668.10 ETO02735.1 - 0.016 14.3 0.0 0.033 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop ATPase protein family NYD-SP28_assoc PF14775.1 ETO02735.1 - 0.033 13.8 12.6 18 5.1 0.0 7.9 11 0 0 11 11 11 0 Sperm tail C-terminal domain DUF1652 PF07865.6 ETO02735.1 - 0.038 13.5 0.0 13 5.4 0.0 4.8 5 2 2 7 7 7 0 Protein of unknown function (DUF1652) DUF258 PF03193.11 ETO02735.1 - 0.046 12.9 0.0 0.12 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PD40 PF07676.7 ETO02735.1 - 0.58 9.8 15.6 23 4.7 0.0 6.4 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat RPEL PF02755.10 ETO02737.1 - 2.8e-11 42.3 6.5 0.00033 19.8 0.1 3.9 4 0 0 4 4 4 3 RPEL repeat SseB_C PF14581.1 ETO02737.1 - 0.0075 16.1 0.1 0.012 15.4 0.0 1.4 1 1 0 1 1 1 1 SseB protein C-terminal domain SIMPL PF04402.9 ETO02737.1 - 0.1 12.4 0.2 0.15 11.9 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF541) Macoilin PF09726.4 ETO02737.1 - 0.15 10.3 2.1 0.17 10.1 1.4 1.0 1 0 0 1 1 1 0 Transmembrane protein HORMA PF02301.13 ETO02737.1 - 0.23 10.9 2.0 0.33 10.3 1.4 1.3 1 1 0 1 1 1 0 HORMA domain PVL_ORF50 PF07768.6 ETO02737.1 - 0.71 9.8 4.2 1.2 9.1 0.4 2.0 1 1 1 2 2 2 0 PVL ORF-50-like family WD40 PF00400.27 ETO02738.1 - 1.7e-08 34.0 3.8 0.00019 21.1 0.3 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat zf-RING_2 PF13639.1 ETO02739.1 - 5.9e-06 26.0 3.2 5.9e-06 26.0 2.2 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 ETO02739.1 - 4.1e-05 23.1 2.2 0.00015 21.3 1.5 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETO02739.1 - 0.0034 17.4 2.3 0.0034 17.4 1.6 2.1 2 1 0 2 2 2 1 RING-H2 zinc finger Fer4_18 PF13746.1 ETO02739.1 - 0.47 10.8 8.0 0.17 12.3 0.6 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain zf-C3HC4_4 PF15227.1 ETO02739.1 - 4.4 7.2 10.3 17 5.3 0.1 3.4 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING Cbl_N PF02262.11 ETO02740.1 - 0.069 12.8 1.5 0.12 12.0 1.0 1.5 1 1 0 1 1 1 0 CBL proto-oncogene N-terminal domain 1 DUF975 PF06161.6 ETO02740.1 - 0.11 12.2 2.8 0.14 11.8 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF975) EntA_Immun PF08951.5 ETO02740.1 - 0.83 9.8 4.3 16 5.7 0.3 3.0 2 1 1 3 3 3 0 Enterocin A Immunity DUF258 PF03193.11 ETO02742.1 - 2e-06 27.0 0.4 1.2e-05 24.6 0.3 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 ETO02742.1 - 1.3e-05 25.1 1.0 3.6e-05 23.6 0.4 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.22 ETO02742.1 - 0.00011 22.5 0.3 0.00015 22.0 0.2 1.3 1 1 0 1 1 1 1 ABC transporter Dynamin_N PF00350.18 ETO02742.1 - 0.00015 21.6 1.5 0.11 12.2 0.0 2.4 1 1 1 2 2 2 2 Dynamin family AAA_29 PF13555.1 ETO02742.1 - 0.00083 18.8 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 ETO02742.1 - 0.0021 18.3 0.5 0.0038 17.5 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 ETO02742.1 - 0.0065 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 ETO02742.1 - 0.0076 15.1 0.1 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 ETO02742.1 - 0.0091 16.1 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 ETO02742.1 - 0.0092 14.7 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain G-alpha PF00503.15 ETO02742.1 - 0.0097 14.6 0.0 0.056 12.1 0.0 1.9 1 1 0 1 1 1 1 G-protein alpha subunit Miro PF08477.8 ETO02742.1 - 0.011 16.2 0.0 0.023 15.1 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Septin PF00735.13 ETO02742.1 - 0.013 14.5 0.1 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Septin GTP_EFTU PF00009.22 ETO02742.1 - 0.019 14.3 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain SRP54 PF00448.17 ETO02742.1 - 0.02 14.3 0.1 0.054 12.9 0.1 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain DUF815 PF05673.8 ETO02742.1 - 0.024 13.5 0.3 0.045 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.4 ETO02742.1 - 0.028 13.9 0.0 0.07 12.6 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 ETO02742.1 - 0.03 14.2 0.3 0.06 13.3 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETO02742.1 - 0.054 13.4 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain PhoH PF02562.11 ETO02742.1 - 0.062 12.5 0.2 0.11 11.6 0.1 1.5 2 0 0 2 2 2 0 PhoH-like protein AAA_17 PF13207.1 ETO02742.1 - 0.066 14.0 0.0 0.12 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 ETO02742.1 - 0.068 13.0 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 ETO02742.1 - 0.069 12.7 0.1 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 RuvB_N PF05496.7 ETO02742.1 - 0.096 11.7 0.1 1.2 8.0 0.0 2.0 1 1 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Sigma54_activ_2 PF14532.1 ETO02742.1 - 0.11 12.4 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 ETO02743.1 - 0.02 14.5 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 NACHT domain rve_2 PF13333.1 ETO02743.1 - 0.077 13.0 1.2 1.4 9.0 0.4 2.8 2 1 0 2 2 2 0 Integrase core domain Peptidase_C14 PF00656.17 ETO02744.1 - 0.00057 19.6 0.1 0.00072 19.3 0.1 1.1 1 0 0 1 1 1 1 Caspase domain z-alpha PF02295.12 ETO02744.1 - 0.14 11.9 1.1 0.19 11.5 0.3 1.5 2 0 0 2 2 2 0 Adenosine deaminase z-alpha domain TPR_12 PF13424.1 ETO02745.1 - 2.8e-74 245.0 13.6 8e-24 83.3 0.3 3.2 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO02745.1 - 1.5e-30 104.2 0.0 6.8e-08 32.1 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO02745.1 - 3.6e-30 102.3 17.5 3.8e-11 42.1 1.3 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO02745.1 - 2.2e-27 92.6 2.0 1.1e-06 27.9 0.0 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO02745.1 - 6.8e-24 83.3 8.9 9e-16 57.2 1.3 2.6 2 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 ETO02745.1 - 1.7e-20 71.2 10.2 4.8e-07 29.2 0.3 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO02745.1 - 5.3e-20 69.6 20.6 1.8e-08 33.5 1.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO02745.1 - 2e-13 49.3 11.3 0.0013 18.7 0.0 5.3 3 2 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO02745.1 - 5.9e-09 35.7 0.0 0.2 12.3 0.0 4.0 4 1 0 4 4 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO02745.1 - 2e-08 34.6 0.0 0.0036 17.9 0.0 3.3 2 2 1 3 3 3 2 Tetratricopeptide repeat MIT PF04212.13 ETO02745.1 - 1.7e-07 31.0 12.5 0.016 15.0 0.2 3.4 3 1 1 4 4 3 3 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 ETO02745.1 - 3.9e-07 29.7 5.7 0.081 12.7 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO02745.1 - 1e-05 25.6 4.9 0.0015 18.6 1.6 2.9 1 1 3 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETO02745.1 - 2.3e-05 24.5 0.7 0.51 10.9 0.0 4.1 4 1 0 4 4 4 1 Tetratricopeptide repeat PPR PF01535.15 ETO02745.1 - 4.9e-05 23.0 3.2 0.1 12.6 0.1 3.5 3 0 0 3 3 3 1 PPR repeat TPR_19 PF14559.1 ETO02745.1 - 7e-05 23.0 0.1 0.013 15.8 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO02745.1 - 0.00013 21.7 6.0 0.34 10.8 0.2 4.1 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat Pep3_Vps18 PF05131.9 ETO02745.1 - 0.0016 17.9 0.4 3.1 7.2 0.0 3.2 2 1 1 3 3 3 1 Pep3/Vps18/deep orange family DUF627 PF04781.7 ETO02745.1 - 0.0071 15.9 2.2 0.46 10.1 0.4 3.3 1 1 2 3 3 3 1 Protein of unknown function (DUF627) DUF2977 PF11192.3 ETO02745.1 - 0.017 14.9 0.1 39 4.1 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2977) KH_4 PF13083.1 ETO02745.1 - 0.048 13.2 0.0 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 KH domain TPR_5 PF12688.2 ETO02745.1 - 0.085 12.8 0.1 8.3 6.4 0.0 2.8 1 1 2 3 3 3 0 Tetratrico peptide repeat EzrA PF06160.7 ETO02745.1 - 0.09 10.9 0.5 12 3.8 0.0 2.7 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA MCM_N PF14551.1 ETO02745.1 - 0.12 12.9 0.7 2.5 8.5 0.5 2.5 1 1 0 1 1 1 0 MCM N-terminal domain SHNi-TPR PF10516.4 ETO02745.1 - 0.15 11.2 0.3 9.1 5.6 0.0 3.4 4 0 0 4 4 4 0 SHNi-TPR P22_AR_C PF10548.4 ETO02745.1 - 0.16 11.8 1.1 41 4.1 0.0 3.4 4 0 0 4 4 4 0 P22AR C-terminal domain DUF1936 PF09151.5 ETO02745.1 - 0.25 10.8 3.4 26 4.4 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1936) IL3 PF02059.10 ETO02746.1 - 0.022 14.7 0.0 0.027 14.4 0.0 1.1 1 0 0 1 1 1 0 Interleukin-3 Xpo1 PF08389.7 ETO02746.1 - 0.2 11.5 1.2 0.29 11.0 0.9 1.4 1 1 0 1 1 1 0 Exportin 1-like protein AIRS PF00586.19 ETO02749.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 AIR synthase related protein, N-terminal domain CSD PF00313.17 ETO02750.1 - 0.00043 20.0 0.1 0.024 14.4 0.0 2.9 3 0 0 3 3 3 2 'Cold-shock' DNA-binding domain TBCA PF02970.11 ETO02751.1 - 2.1e-17 62.9 10.3 2.5e-17 62.7 7.1 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A ApoLp-III PF07464.6 ETO02751.1 - 0.014 15.4 6.2 0.017 15.1 4.3 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) CobN-Mg_chel PF02514.11 ETO02751.1 - 0.014 12.8 4.1 0.016 12.6 2.8 1.0 1 0 0 1 1 1 0 CobN/Magnesium Chelatase Histone PF00125.19 ETO02751.1 - 0.038 14.1 0.4 0.41 10.7 0.0 2.1 1 1 1 2 2 2 0 Core histone H2A/H2B/H3/H4 PilJ PF13675.1 ETO02751.1 - 0.045 14.0 3.4 0.4 11.0 1.7 2.0 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF244 PF03112.9 ETO02751.1 - 0.079 12.5 2.7 0.1 12.1 1.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF DUF4164 PF13747.1 ETO02751.1 - 0.23 11.6 7.5 0.44 10.7 5.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) AAA_13 PF13166.1 ETO02751.1 - 0.26 9.7 5.9 0.27 9.6 4.1 1.1 1 0 0 1 1 1 0 AAA domain TMPIT PF07851.8 ETO02751.1 - 0.36 9.8 3.9 0.42 9.6 2.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF2570 PF10828.3 ETO02751.1 - 0.41 10.2 7.4 0.88 9.2 5.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) Spc7 PF08317.6 ETO02751.1 - 0.43 9.1 10.4 0.2 10.3 2.6 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF641 PF04859.7 ETO02751.1 - 0.64 9.7 8.3 0.43 10.3 3.6 1.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) FlxA PF14282.1 ETO02751.1 - 0.8 9.6 9.6 0.66 9.9 5.5 1.7 1 1 1 2 2 2 0 FlxA-like protein DUF342 PF03961.8 ETO02751.1 - 1.1 7.6 7.8 1.2 7.4 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 ETO02751.1 - 2 7.4 8.3 2.1 7.3 5.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 ETO02751.1 - 2.2 5.9 4.6 2.2 6.0 3.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3987 PF13148.1 ETO02751.1 - 2.3 6.7 6.4 2.6 6.5 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF972 PF06156.8 ETO02751.1 - 4.5 7.6 8.5 7.3 6.9 5.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Gin PF10764.4 ETO02752.1 - 0.018 14.7 0.3 0.045 13.4 0.2 1.6 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin DnaJ PF00226.26 ETO02753.1 - 8e-05 22.2 0.0 0.00018 21.1 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.27 ETO02754.1 - 1.1e-67 221.6 13.8 1.2e-14 53.5 0.1 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO02754.1 - 1.3e-08 33.5 1.5 0.068 11.2 0.1 4.2 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO02754.1 - 3.5e-07 28.8 0.9 0.026 12.8 0.1 3.1 1 1 3 4 4 4 4 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO02754.1 - 7.6e-07 28.5 1.7 0.069 12.2 0.0 3.5 1 1 3 4 4 4 2 Neuroblastoma-amplified sequence, N terminal NYD-SP28_assoc PF14775.1 ETO02754.1 - 3.1e-06 26.7 0.3 6.6 6.5 0.0 4.8 5 0 0 5 5 5 1 Sperm tail C-terminal domain PD40 PF07676.7 ETO02754.1 - 4.5e-06 26.2 3.4 9.2 6.0 0.0 4.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO02754.1 - 5.5e-06 26.0 0.7 0.0039 16.6 0.0 2.1 1 1 0 2 2 2 2 PQQ-like domain DUF1258 PF06869.7 ETO02754.1 - 0.00012 21.3 0.0 0.65 9.0 0.0 3.3 1 1 1 3 3 3 2 Protein of unknown function (DUF1258) DUF727 PF05303.7 ETO02754.1 - 0.00013 21.6 0.0 7.1 6.4 0.0 3.9 1 1 3 4 4 4 1 Protein of unknown function (DUF727) BBS2_Mid PF14783.1 ETO02754.1 - 0.00029 20.6 0.4 3.7 7.3 0.0 4.4 1 1 3 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Proteasome_A_N PF10584.4 ETO02754.1 - 0.0005 19.3 5.6 18 4.7 0.0 4.8 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature PQQ_3 PF13570.1 ETO02754.1 - 0.0021 18.2 0.2 17 5.8 0.0 4.0 3 1 2 5 5 4 0 PQQ-like domain TolB_N PF04052.8 ETO02754.1 - 0.0032 17.5 0.0 33 4.6 0.0 4.6 5 0 0 5 5 5 0 TolB amino-terminal domain Gmad1 PF10647.4 ETO02754.1 - 0.0038 16.6 0.1 0.02 14.2 0.1 2.1 1 1 2 3 3 3 1 Lipoprotein LpqB beta-propeller domain SLH PF00395.15 ETO02754.1 - 0.0061 16.2 0.0 27 4.5 0.0 4.0 4 0 0 4 4 4 0 S-layer homology domain DUF3312 PF11768.3 ETO02754.1 - 0.0079 14.4 0.0 1.3 7.1 0.0 2.8 1 1 0 2 2 2 1 Protein of unknown function (DUF3312) DUF1652 PF07865.6 ETO02754.1 - 0.038 13.5 0.0 37 4.0 0.0 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF1652) DUF3475 PF11961.3 ETO02754.1 - 0.072 12.9 0.2 47 3.9 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3475) USP7_C2 PF14533.1 ETO02754.1 - 0.13 11.7 0.1 43 3.4 0.0 3.9 2 2 2 4 4 4 0 Ubiquitin-specific protease C-terminal CH PF00307.26 ETO02755.1 - 2.1e-16 59.8 0.1 3e-10 40.1 0.0 3.0 2 1 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 ETO02755.1 - 0.017 14.7 0.0 0.14 11.8 0.0 2.4 2 0 0 2 2 2 0 CAMSAP CH domain Chordopox_G3 PF06129.7 ETO02756.1 - 1.9 8.6 9.2 1.2 9.2 2.9 2.7 1 1 1 2 2 2 0 Chordopoxvirus G3 protein SPATIAL PF15256.1 ETO02757.1 - 0.061 13.3 0.8 0.069 13.2 0.6 1.1 1 0 0 1 1 1 0 SPATIAL Ras PF00071.17 ETO02758.1 - 0.0011 18.3 0.1 0.0032 16.8 0.0 1.8 1 0 0 1 1 1 1 Ras family DUF3608 PF12257.3 ETO02760.1 - 0.0014 17.6 0.6 0.0015 17.4 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DUF3642 PF12182.3 ETO02760.1 - 0.026 14.9 3.8 0.1 13.0 0.6 2.5 1 1 0 2 2 2 0 Bacterial lipoprotein CorA PF01544.13 ETO02761.1 - 0.26 10.3 4.2 0.12 11.4 0.9 1.7 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein HalX PF08663.5 ETO02761.1 - 7.4 6.6 7.6 1.5 8.8 0.1 2.7 3 0 0 3 3 3 0 HalX domain MazG-like PF12643.2 ETO02761.1 - 7.6 6.5 12.2 19 5.2 2.7 3.2 2 2 0 2 2 2 0 MazG-like family tRNA-synt_His PF13393.1 ETO02761.1 - 9.8 5.1 6.9 5.5 5.9 1.2 2.0 1 1 0 2 2 2 0 Histidyl-tRNA synthetase CUE PF02845.11 ETO02762.1 - 0.0062 15.9 0.2 0.011 15.2 0.1 1.4 1 1 0 1 1 1 1 CUE domain UBA PF00627.26 ETO02762.1 - 0.01 15.6 0.1 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 UBA/TS-N domain Suc_Fer-like PF06999.7 ETO02762.1 - 0.05 13.6 0.6 0.058 13.4 0.4 1.1 1 0 0 1 1 1 0 Sucrase/ferredoxin-like BSMAP PF12280.3 ETO02762.1 - 0.071 12.9 0.2 0.085 12.7 0.2 1.1 1 0 0 1 1 1 0 Brain specific membrane anchored protein Iron_permease PF04120.7 ETO02762.1 - 2.4 7.7 4.8 3.4 7.2 3.2 1.3 1 1 0 1 1 1 0 Low affinity iron permease Phage_GP20 PF06810.6 ETO02763.1 - 0.00014 21.3 18.4 0.00014 21.3 12.8 3.3 1 1 2 3 3 3 1 Phage minor structural protein GP20 NPV_P10 PF05531.7 ETO02763.1 - 0.014 15.6 3.0 0.014 15.6 2.1 3.3 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 ETO02763.1 - 0.029 13.5 2.0 0.043 13.0 1.4 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF4045 PF13254.1 ETO02763.1 - 1.3 8.2 20.1 1.6 7.9 14.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Bac_GDH PF05088.7 ETO02763.1 - 1.7 5.9 18.6 2 5.6 12.9 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase DUF3866 PF12982.2 ETO02763.1 - 1.8 7.4 6.2 0.36 9.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3866) AATF-Che1 PF13339.1 ETO02763.1 - 4.1 7.5 28.5 19 5.4 10.4 2.6 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor DUF3944 PF13099.1 ETO02764.1 - 0.0019 17.6 1.1 0.017 14.6 0.2 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3944) HEAT_2 PF13646.1 ETO02764.1 - 0.0088 16.3 0.0 0.013 15.8 0.0 1.5 1 1 0 1 1 1 1 HEAT repeats Rieske PF00355.21 ETO02764.1 - 0.024 14.2 0.0 0.3 10.6 0.0 2.1 2 0 0 2 2 2 0 Rieske [2Fe-2S] domain DUF4485 PF14846.1 ETO02764.1 - 0.087 12.5 1.1 0.17 11.6 0.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4485) U-box PF04564.10 ETO02765.1 - 2.4e-12 46.6 0.3 8.6e-12 44.8 0.0 2.1 2 1 0 2 2 2 1 U-box domain SAM_1 PF00536.25 ETO02765.1 - 0.059 13.5 0.2 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) RhoGEF PF00621.15 ETO02768.1 - 2.6e-20 73.0 21.2 1.4e-12 47.8 5.5 3.0 2 1 0 2 2 2 2 RhoGEF domain Macscav_rec PF03523.8 ETO02768.1 - 0.17 11.6 3.8 3.3 7.5 0.7 2.6 2 0 0 2 2 2 0 Macrophage scavenger receptor FYVE PF01363.16 ETO02769.1 - 9.1e-08 31.8 2.8 1.8e-07 30.9 2.0 1.6 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 ETO02769.1 - 0.0016 18.6 0.1 0.0087 16.2 0.1 2.2 1 1 0 1 1 1 1 PH domain IBR PF01485.16 ETO02769.1 - 0.14 12.0 8.2 0.37 10.7 5.7 1.7 1 0 0 1 1 1 0 IBR domain Prothymosin PF03247.9 ETO02770.1 - 0.023 14.8 22.6 0.034 14.2 15.7 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family AIF-MLS PF14962.1 ETO02770.1 - 0.077 12.6 8.8 0.1 12.2 6.1 1.1 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Pyr_excise PF03013.9 ETO02770.1 - 0.12 12.1 6.0 0.15 11.8 4.2 1.2 1 0 0 1 1 1 0 Pyrimidine dimer DNA glycosylase Zip PF02535.17 ETO02770.1 - 0.2 10.6 3.3 0.2 10.6 2.3 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter UPF0565 PF10561.4 ETO02770.1 - 0.59 8.9 4.8 0.7 8.7 3.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 ATP-synt_B PF00430.13 ETO02770.1 - 0.93 9.2 12.5 1.1 9.0 8.7 1.1 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF1510 PF07423.6 ETO02770.1 - 1 8.6 18.9 1.2 8.4 13.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Spore_coat_CotO PF14153.1 ETO02770.1 - 1 8.7 20.3 1.3 8.4 14.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO BSMAP PF12280.3 ETO02770.1 - 1.1 9.1 5.8 1.1 9.0 4.0 1.1 1 0 0 1 1 1 0 Brain specific membrane anchored protein TCP PF03634.8 ETO02770.1 - 1.2 9.4 8.0 1.5 9.2 5.5 1.0 1 0 0 1 1 1 0 TCP family transcription factor F-protein PF00469.15 ETO02770.1 - 1.3 8.3 9.9 1.4 8.2 6.9 1.0 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef DDHD PF02862.12 ETO02770.1 - 1.5 8.5 10.1 1.7 8.4 7.0 1.0 1 0 0 1 1 1 0 DDHD domain Caldesmon PF02029.10 ETO02770.1 - 1.5 7.1 22.6 1.7 6.9 15.7 1.0 1 0 0 1 1 1 0 Caldesmon CobT PF06213.7 ETO02770.1 - 1.8 7.5 14.2 2.1 7.4 9.8 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RP-C_C PF11800.3 ETO02770.1 - 2 8.0 10.2 2.3 7.8 7.1 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF2992 PF11208.3 ETO02770.1 - 2.1 8.2 16.5 2.5 7.9 11.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Raftlin PF15250.1 ETO02770.1 - 2.1 6.7 9.7 2.4 6.5 6.7 1.0 1 0 0 1 1 1 0 Raftlin VID27 PF08553.5 ETO02770.1 - 2.3 6.3 15.0 2.7 6.0 10.4 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Hid1 PF12722.2 ETO02770.1 - 2.7 5.5 10.2 3.1 5.3 7.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAE2 PF08573.5 ETO02770.1 - 2.8 8.7 9.8 3.4 8.4 6.8 1.1 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus DUF2201_N PF13203.1 ETO02770.1 - 3.6 6.6 9.8 3.9 6.5 6.8 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain Vfa1 PF08432.5 ETO02770.1 - 3.8 7.4 19.2 4.6 7.2 13.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CRT10 PF08728.5 ETO02770.1 - 4 5.3 7.1 4.6 5.0 5.0 1.0 1 0 0 1 1 1 0 CRT10 SprA-related PF12118.3 ETO02770.1 - 4.3 6.5 17.7 4.7 6.4 12.3 1.0 1 0 0 1 1 1 0 SprA-related family DUF1800 PF08811.6 ETO02770.1 - 4.7 6.0 7.8 5.4 5.8 5.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) CDC45 PF02724.9 ETO02770.1 - 4.8 5.1 12.6 5.6 4.8 8.7 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2146 PF10220.4 ETO02770.1 - 5.2 4.9 10.1 5.7 4.7 7.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Band_3_cyto PF07565.8 ETO02770.1 - 5.3 6.4 7.2 5.6 6.4 5.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Serinc PF03348.10 ETO02770.1 - 5.3 5.6 6.3 5.7 5.5 4.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Sec62 PF03839.11 ETO02770.1 - 5.5 6.3 14.7 6.5 6.0 10.2 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 Ycf1 PF05758.7 ETO02770.1 - 5.7 4.5 14.6 6.2 4.3 10.1 1.0 1 0 0 1 1 1 0 Ycf1 DUF4175 PF13779.1 ETO02770.1 - 6 4.4 16.4 6.8 4.2 11.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Neur_chan_memb PF02932.11 ETO02770.1 - 6.1 6.6 7.3 7.2 6.4 5.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TRAP_alpha PF03896.11 ETO02770.1 - 6.5 5.6 8.7 7.2 5.5 6.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RR_TM4-6 PF06459.7 ETO02770.1 - 6.8 6.4 19.2 7.3 6.4 13.3 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MRP-S26 PF14943.1 ETO02770.1 - 9.4 5.7 21.5 11 5.4 14.9 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 HSP90 PF00183.13 ETO02771.1 - 9.2e-63 212.4 22.3 7.8e-44 149.9 6.8 3.8 2 1 1 3 3 3 3 Hsp90 protein zf-C2H2_jaz PF12171.3 ETO02771.1 - 1.3 9.2 6.5 0.4 10.8 1.6 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding T2SE PF00437.15 ETO02772.1 - 0.0008 18.3 0.1 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.22 ETO02772.1 - 0.001 19.3 4.5 0.002 18.4 0.1 2.2 2 1 0 2 2 2 1 ABC transporter DUF258 PF03193.11 ETO02772.1 - 0.0028 16.8 0.9 0.0084 15.3 0.3 2.0 1 1 2 3 3 3 1 Protein of unknown function, DUF258 PhoH PF02562.11 ETO02772.1 - 0.0046 16.2 0.1 0.019 14.1 0.0 1.9 2 0 0 2 2 2 1 PhoH-like protein AAA_29 PF13555.1 ETO02772.1 - 0.0065 15.9 0.1 0.017 14.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF815 PF05673.8 ETO02772.1 - 0.0066 15.4 0.1 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Miro PF08477.8 ETO02772.1 - 0.011 16.1 0.3 0.1 13.0 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein AAA_25 PF13481.1 ETO02772.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 ETO02772.1 - 0.025 14.0 0.1 0.038 13.4 0.1 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.17 ETO02772.1 - 0.039 14.1 2.0 0.47 10.6 0.0 2.9 2 1 0 2 2 2 0 RNA helicase AAA_19 PF13245.1 ETO02772.1 - 0.04 13.6 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 ETO02772.1 - 0.04 13.8 0.0 0.086 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 ETO02772.1 - 0.069 12.2 0.2 0.29 10.1 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin Sigma54_activ_2 PF14532.1 ETO02772.1 - 0.086 12.8 0.1 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 ETO02772.1 - 0.086 12.2 1.2 0.27 10.6 0.2 2.2 2 1 0 2 2 2 0 IstB-like ATP binding protein AAA_22 PF13401.1 ETO02772.1 - 0.088 12.9 0.0 0.26 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 ETO02772.1 - 0.091 12.2 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_33 PF13671.1 ETO02772.1 - 0.12 12.2 0.2 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 ETO02772.1 - 0.16 11.1 3.4 0.37 10.0 0.2 2.8 3 1 0 3 3 3 0 ADP-ribosylation factor family AAA_28 PF13521.1 ETO02772.1 - 0.17 11.8 0.3 0.17 11.8 0.2 1.6 2 0 0 2 2 1 0 AAA domain Sterile PF03015.14 ETO02772.1 - 0.59 10.4 3.8 1.5 9.1 2.7 1.6 1 1 0 1 1 1 0 Male sterility protein DUF87 PF01935.12 ETO02772.1 - 2.4 7.9 6.5 0.29 10.9 0.8 2.0 1 1 1 2 2 2 0 Domain of unknown function DUF87 AAA_23 PF13476.1 ETO02772.1 - 4.2 7.6 13.1 0.41 10.9 0.5 2.2 1 1 1 2 2 2 0 AAA domain WD40 PF00400.27 ETO02773.1 - 2.7e-38 128.4 13.2 3.8e-13 48.7 0.1 4.5 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO02773.1 - 4.1e-07 28.5 1.1 0.00082 17.6 0.1 3.0 1 1 2 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO02773.1 - 2.5e-05 24.1 0.0 0.036 13.7 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO02773.1 - 0.00017 20.0 0.1 0.057 11.7 0.0 2.2 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO02773.1 - 0.00098 17.9 6.6 0.38 9.4 0.1 3.3 1 1 1 2 2 2 2 Nup133 N terminal like DUF1258 PF06869.7 ETO02773.1 - 0.033 13.2 0.2 0.22 10.5 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) SGL PF08450.7 ETO02773.1 - 0.043 13.1 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region Mid2 PF04478.7 ETO02773.1 - 0.084 12.2 1.0 9.7 5.5 0.0 2.8 2 1 1 3 3 3 0 Mid2 like cell wall stress sensor Str_synth PF03088.11 ETO02773.1 - 0.12 12.3 0.2 1.2 9.1 0.0 2.6 3 1 0 3 3 3 0 Strictosidine synthase Proteasome_A_N PF10584.4 ETO02773.1 - 4.2 6.7 9.2 5.4 6.4 0.0 3.7 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature HALZ PF02183.13 ETO02777.1 - 0.00025 20.6 4.1 0.033 13.9 1.2 2.4 2 0 0 2 2 2 2 Homeobox associated leucine zipper Tektin PF03148.9 ETO02777.1 - 0.0055 15.3 3.1 0.0068 14.9 2.1 1.2 1 0 0 1 1 1 1 Tektin family Sec34 PF04136.10 ETO02777.1 - 0.05 13.2 4.2 0.066 12.9 2.9 1.4 1 1 0 1 1 1 0 Sec34-like family THP2 PF09432.5 ETO02777.1 - 0.095 12.5 1.6 0.2 11.5 0.8 1.7 1 1 1 2 2 2 0 Tho complex subunit THP2 DUF607 PF04678.8 ETO02777.1 - 0.16 11.8 1.1 0.16 11.8 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF607 DUF1664 PF07889.7 ETO02777.1 - 0.21 11.4 3.3 0.25 11.1 2.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Spc24 PF08286.6 ETO02777.1 - 0.64 9.7 7.4 1.7 8.3 2.9 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 H-kinase_dim PF02895.9 ETO02777.1 - 0.74 10.1 4.1 1.2 9.4 2.8 1.4 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain DivIC PF04977.10 ETO02777.1 - 1.7 8.1 8.3 14 5.2 3.5 2.2 2 1 0 2 2 2 0 Septum formation initiator FliD_N PF02465.13 ETO02777.1 - 2.1 8.7 5.1 4.1 7.8 2.2 1.9 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF904 PF06005.7 ETO02777.1 - 4.7 7.5 11.3 1.1e+02 3.2 7.8 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Anoctamin PF04547.7 ETO02780.1 - 7.7e-74 248.9 0.1 9.8e-74 248.6 0.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel SAM_1 PF00536.25 ETO02780.1 - 0.0002 21.4 0.0 0.00041 20.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO02780.1 - 0.00027 20.7 0.0 0.00058 19.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 ETO02780.1 - 0.0028 17.3 0.0 0.94 9.2 0.0 2.5 2 0 0 2 2 2 2 Sterile alpha motif (SAM)/Pointed domain PilM PF07419.7 ETO02781.1 - 0.036 13.5 0.2 0.051 13.0 0.1 1.2 1 0 0 1 1 1 0 PilM DUF155 PF02582.9 ETO02782.1 - 0.01 15.7 1.4 0.01 15.7 1.0 2.2 2 0 0 2 2 2 0 Uncharacterised ACR, YagE family COG1723 DUF1515 PF07439.6 ETO02782.1 - 0.041 13.6 5.4 0.24 11.2 1.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) Apolipoprotein PF01442.13 ETO02782.1 - 0.066 12.7 7.1 0.4 10.1 0.0 2.8 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain Trans_reg_C PF00486.23 ETO02782.1 - 0.067 13.1 0.6 0.32 10.9 0.4 2.2 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal Fe-S_assembly PF04384.8 ETO02782.1 - 0.073 13.4 3.1 1.1 9.6 0.3 3.1 2 0 0 2 2 2 0 Iron-sulphur cluster assembly Syntaxin PF00804.20 ETO02782.1 - 0.18 12.0 17.1 0.19 11.8 0.1 4.4 4 0 0 4 4 4 0 Syntaxin DUF972 PF06156.8 ETO02782.1 - 0.26 11.6 21.2 1.7 9.0 0.0 4.3 3 2 2 5 5 5 0 Protein of unknown function (DUF972) DDE_Tnp_IS240 PF13610.1 ETO02782.1 - 0.32 10.9 8.5 0.051 13.5 0.9 3.0 2 1 1 3 3 3 0 DDE domain Fork_head PF00250.13 ETO02782.1 - 0.47 10.5 5.9 18 5.4 0.0 2.8 2 0 0 2 2 2 0 Fork head domain HR1 PF02185.11 ETO02782.1 - 6.1 6.6 17.7 0.43 10.3 2.2 3.7 4 0 0 4 4 4 0 Hr1 repeat TPR_12 PF13424.1 ETO02783.1 - 1.5e-40 136.9 19.0 3.6e-20 71.6 0.9 2.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO02783.1 - 2.9e-28 97.3 32.7 9.4e-14 50.8 5.7 3.2 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETO02783.1 - 3.7e-21 73.7 22.8 1.4e-08 33.9 0.9 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO02783.1 - 6.8e-21 72.4 15.7 1.4e-07 30.8 0.3 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO02783.1 - 7e-17 60.7 0.5 1.6e-06 27.8 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO02783.1 - 2.8e-13 48.5 5.1 5e-05 22.7 0.1 3.6 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO02783.1 - 2.5e-12 45.6 25.1 6.7e-06 25.5 1.5 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO02783.1 - 1.5e-10 40.8 0.4 0.0027 18.0 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO02783.1 - 5.9e-09 36.3 0.4 2.7e-05 24.7 0.3 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO02783.1 - 8.4e-08 32.1 0.0 0.049 14.2 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO02783.1 - 2.2e-07 30.5 15.1 0.025 14.7 1.4 4.2 4 1 0 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 ETO02783.1 - 5e-07 29.7 13.4 4.9e-05 23.3 4.1 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 ETO02783.1 - 4.3e-06 26.4 5.0 2.2e-05 24.1 0.8 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat SNAP PF14938.1 ETO02783.1 - 7.5e-05 22.0 8.0 0.00032 19.9 5.4 1.9 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_5 PF12688.2 ETO02783.1 - 0.00025 21.0 1.0 0.61 10.1 0.0 3.0 2 1 1 3 3 3 2 Tetratrico peptide repeat DUF2225 PF09986.4 ETO02783.1 - 0.00028 20.4 9.2 0.0013 18.2 1.5 2.0 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) PPR PF01535.15 ETO02783.1 - 0.00033 20.4 6.2 0.17 11.8 0.1 3.8 3 2 1 4 4 4 1 PPR repeat RPN7 PF10602.4 ETO02783.1 - 0.00043 19.7 7.7 0.07 12.4 0.9 3.0 1 1 1 3 3 3 2 26S proteasome subunit RPN7 SHNi-TPR PF10516.4 ETO02783.1 - 0.00097 18.3 2.1 0.59 9.4 0.1 3.1 4 0 0 4 4 4 2 SHNi-TPR TPR_19 PF14559.1 ETO02783.1 - 0.0015 18.8 3.1 0.011 16.0 0.7 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat Prefoldin PF02996.12 ETO02783.1 - 0.0032 17.0 3.5 0.31 10.6 0.2 3.0 2 1 1 3 3 3 1 Prefoldin subunit MIT PF04212.13 ETO02783.1 - 0.012 15.4 11.2 0.027 14.3 0.6 3.4 3 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain Foie-gras_1 PF11817.3 ETO02783.1 - 0.016 14.7 1.7 0.22 10.9 1.2 2.5 1 1 0 1 1 1 0 Foie gras liver health family 1 TPR_9 PF13371.1 ETO02783.1 - 0.021 14.6 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Sel1 PF08238.7 ETO02783.1 - 0.031 14.8 3.4 0.7 10.6 0.0 3.3 3 0 0 3 3 3 0 Sel1 repeat NSF PF02071.15 ETO02783.1 - 0.038 14.4 7.1 3.2 8.7 0.2 4.5 4 0 0 4 4 4 0 Aromatic-di-Alanine (AdAR) repeat DUF1910 PF08928.5 ETO02783.1 - 0.055 13.4 5.2 0.32 11.0 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) DUF627 PF04781.7 ETO02783.1 - 0.11 12.0 1.9 2.6 7.6 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF627) OEP PF02321.13 ETO02783.1 - 0.63 9.6 5.0 0.78 9.2 0.2 2.2 1 1 2 3 3 3 0 Outer membrane efflux protein SPO22 PF08631.5 ETO02783.1 - 0.92 8.5 9.5 2.1 7.3 0.3 3.0 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like DUF4080 PF13311.1 ETO02783.1 - 1 9.3 10.0 3.6 7.5 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4080) Sec5 PF15469.1 ETO02783.1 - 2.6 7.7 7.3 5.4 6.6 4.4 2.1 1 1 1 2 2 2 0 Exocyst complex component Sec5 PPR_2 PF13041.1 ETO02783.1 - 5.6 7.0 6.9 11 6.1 0.1 3.0 3 0 0 3 3 3 0 PPR repeat family TPR_11 PF13414.1 ETO02784.1 - 3.5e-16 58.6 1.0 6.8e-06 25.6 0.5 2.8 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETO02784.1 - 2.6e-11 42.6 2.8 0.0028 17.2 0.0 3.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO02784.1 - 2.2e-10 39.8 1.0 0.0011 18.9 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO02784.1 - 2.8e-06 26.8 0.6 1.1 9.3 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO02784.1 - 1.6e-05 24.7 0.9 0.04 13.8 0.3 2.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO02784.1 - 1.7e-05 25.0 0.1 0.027 15.1 0.0 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO02784.1 - 0.00048 19.7 0.0 0.19 11.5 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO02784.1 - 0.00054 20.2 0.0 0.5 10.7 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO02784.1 - 0.0059 17.2 0.1 0.73 10.5 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO02784.1 - 0.024 14.3 0.1 16 5.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 ETO02784.1 - 0.087 12.7 0.4 4.6 7.3 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Phage_int_SAM_4 PF13495.1 ETO02785.1 - 0.021 15.1 0.3 0.053 13.8 0.2 1.7 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain PUD PF03714.9 ETO02785.1 - 0.069 13.2 1.0 0.069 13.2 0.7 2.2 2 0 0 2 2 2 0 Bacterial pullanase-associated domain IncA PF04156.9 ETO02785.1 - 5.4 6.5 10.7 8.3 5.9 7.4 1.2 1 0 0 1 1 1 0 IncA protein zf-TRAF PF02176.13 ETO02786.1 - 0.00012 22.4 7.2 0.00012 22.4 5.0 2.8 3 1 1 4 4 4 1 TRAF-type zinc finger RNB PF00773.14 ETO02786.1 - 0.048 12.9 0.1 0.053 12.8 0.1 1.2 1 0 0 1 1 1 0 RNB domain HEAT PF02985.17 ETO02787.1 - 2e-07 30.5 0.2 0.00026 20.7 0.0 3.3 3 1 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 ETO02787.1 - 3.3e-05 24.0 0.0 0.00055 20.1 0.0 2.1 1 1 1 2 2 2 1 HEAT repeats HEAT_EZ PF13513.1 ETO02787.1 - 4.8e-05 23.7 0.0 0.00028 21.2 0.0 2.1 2 0 0 2 2 2 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 ETO02787.1 - 0.00042 20.6 0.1 0.032 14.6 0.0 2.1 1 1 1 2 2 2 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 ETO02787.1 - 0.00052 19.9 0.6 0.093 12.5 0.0 1.9 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 ETO02787.1 - 0.0013 18.0 0.0 0.0034 16.7 0.0 1.6 1 1 0 1 1 1 1 CLASP N terminal TIP120 PF08623.5 ETO02787.1 - 0.0032 17.0 0.4 0.31 10.5 0.1 2.2 1 1 1 2 2 2 1 TATA-binding protein interacting (TIP20) Adaptin_N PF01602.15 ETO02787.1 - 0.0034 15.7 0.1 0.0037 15.6 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region DUF3554 PF12074.3 ETO02787.1 - 0.013 14.9 0.4 0.016 14.6 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3554) Zn_ribbon_2 PF12674.2 ETO02787.1 - 0.08 13.2 0.3 2.8 8.3 0.1 2.3 1 1 1 2 2 2 0 Putative zinc ribbon domain Copper-fist PF00649.13 ETO02787.1 - 0.12 11.6 0.3 0.26 10.4 0.2 1.5 1 0 0 1 1 1 0 Copper fist DNA binding domain SRA1 PF07304.6 ETO02787.1 - 0.12 12.0 0.4 0.27 10.9 0.2 1.6 1 1 0 1 1 1 0 Steroid receptor RNA activator (SRA1) NUC130_3NT PF08158.7 ETO02787.1 - 0.17 12.1 0.5 4.9 7.5 0.1 2.9 2 1 0 2 2 2 0 NUC130/3NT domain WD40 PF00400.27 ETO02788.1 - 1.2e-19 69.3 11.8 1.2e-09 37.6 0.5 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO02788.1 - 4e-06 25.2 2.4 0.011 13.8 0.2 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Cys_knot PF00007.17 ETO02789.1 - 0.017 15.1 1.6 2.4 8.2 0.1 2.5 2 0 0 2 2 2 0 Cystine-knot domain DUF2115 PF09888.4 ETO02790.1 - 0.027 14.5 1.2 0.035 14.1 0.8 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) CTK3_C PF12350.3 ETO02791.1 - 0.021 14.8 0.1 0.19 11.7 0.0 2.2 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 C-terminus Sec31 PF11549.3 ETO02792.1 - 0.086 12.4 0.1 0.58 9.8 0.0 2.0 2 0 0 2 2 2 0 Protein transport protein SEC31 DUF706 PF05153.10 ETO02796.1 - 3.1e-10 39.8 1.2 5e-10 39.1 0.8 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF706) DUF262 PF03235.9 ETO02796.1 - 0.073 13.0 5.6 0.085 12.8 3.9 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF262 Cid2 PF09774.4 ETO02796.1 - 0.09 12.8 2.8 0.12 12.4 2.0 1.2 1 0 0 1 1 1 0 Caffeine-induced death protein 2 DUF4408 PF14364.1 ETO02797.1 - 0.21 11.1 2.9 0.43 10.1 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4408) Med17 PF10156.4 ETO02798.1 - 0.019 13.2 0.0 0.028 12.6 0.0 1.3 1 0 0 1 1 1 0 Subunit 17 of Mediator complex DUF3357 PF11837.3 ETO02800.1 - 0.0097 15.7 0.4 0.079 12.8 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3357) GA PF01468.12 ETO02800.1 - 0.076 13.1 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 GA module DUF3336 PF11815.3 ETO02801.1 - 0.11 11.9 1.4 0.36 10.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3336) Orthopox_A5L PF06193.6 ETO02801.1 - 0.25 11.2 3.4 0.31 10.9 1.8 1.5 1 1 0 1 1 1 0 Orthopoxvirus A5L protein-like TPR_12 PF13424.1 ETO02802.1 - 8.2e-17 60.9 0.1 3.9e-13 49.1 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO02802.1 - 3.1e-08 33.2 0.0 5.6e-06 26.1 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO02802.1 - 2.1e-07 30.2 5.7 3.2e-07 29.6 0.4 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO02802.1 - 5.1e-07 29.0 0.0 1.7e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO02802.1 - 1.9e-05 24.1 2.0 5.2e-05 22.8 0.7 2.0 1 1 1 2 2 2 1 TPR repeat TPR_8 PF13181.1 ETO02802.1 - 0.00011 21.7 2.3 0.00011 21.7 1.6 2.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO02802.1 - 0.00012 21.7 1.5 0.00047 19.8 0.1 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO02802.1 - 0.0019 18.2 2.0 3.9 7.8 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat IL6 PF00489.12 ETO02806.1 - 0.01 15.4 1.0 0.01 15.4 0.7 1.9 2 0 0 2 2 2 0 Interleukin-6/G-CSF/MGF family DUF4011 PF13195.1 ETO02806.1 - 2.1 8.3 6.9 4.3 7.3 4.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4011) Got1 PF04178.7 ETO02807.1 - 0.0054 16.8 2.8 0.014 15.4 2.0 1.7 1 0 0 1 1 1 1 Got1/Sft2-like family Vfa1 PF08432.5 ETO02807.1 - 0.94 9.4 21.1 0.29 11.1 5.0 3.3 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 FAM176 PF14851.1 ETO02807.1 - 1.4 8.5 10.7 2.1 8.0 1.6 3.2 3 0 0 3 3 3 0 FAM176 family Peptidase_C48 PF02902.14 ETO02808.1 - 8.6e-19 68.0 2.5 8.6e-19 68.0 1.7 1.7 2 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain PNRC PF15365.1 ETO02810.1 - 0.082 12.9 1.3 0.26 11.3 0.9 1.9 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator Kinesin PF00225.18 ETO02811.1 - 7.2e-31 107.1 0.4 8.5e-31 106.8 0.3 1.0 1 0 0 1 1 1 1 Kinesin motor domain Sugar_tr PF00083.19 ETO02812.1 - 1e-19 70.4 1.6 1e-19 70.4 1.1 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 ETO02812.1 - 0.034 12.8 9.6 0.065 11.9 6.7 1.3 1 1 0 1 1 1 0 Major Facilitator Superfamily Baculo_E56 PF04639.7 ETO02812.1 - 0.12 11.0 1.6 3.1 6.3 0.1 2.1 2 0 0 2 2 2 0 Baculoviral E56 protein, specific to ODV envelope DUF2976 PF11190.3 ETO02812.1 - 0.12 11.9 2.6 1.1 8.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) Rad1 PF02144.11 ETO02815.1 - 0.031 13.0 0.1 0.041 12.6 0.1 1.2 1 0 0 1 1 1 0 Repair protein Rad1/Rec1/Rad17 DUF659 PF04937.10 ETO02815.1 - 0.038 13.4 0.7 0.076 12.5 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) SPARC_Ca_bdg PF10591.4 ETO02815.1 - 0.08 12.9 1.2 0.17 11.9 0.8 1.6 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region PUB PF09409.5 ETO02816.1 - 0.0045 16.7 0.3 0.046 13.4 0.1 2.9 2 1 0 2 2 2 1 PUB domain UCH PF00443.24 ETO02817.1 - 2e-10 40.2 0.1 2.5e-10 39.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase GRP PF07172.6 ETO02817.1 - 0.0026 18.1 7.9 0.0036 17.7 5.5 1.2 1 0 0 1 1 1 1 Glycine rich protein family RRM_1 PF00076.17 ETO02818.1 - 2.3e-07 30.3 0.0 7.5e-07 28.6 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO02818.1 - 1.6e-05 24.6 0.0 3.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.3 ETO02818.1 - 0.0083 15.4 0.0 0.025 13.8 0.0 1.8 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated RRM_6 PF14259.1 ETO02818.1 - 0.019 14.9 0.0 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 ETO02819.1 - 2.5e-20 72.7 3.7 2.5e-20 72.7 2.6 1.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO02819.1 - 1.4e-12 47.2 2.6 3.8e-10 39.2 1.8 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase RAP1 PF07218.6 ETO02819.1 - 0.0037 15.4 23.6 0.004 15.3 16.3 1.1 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) SANTA PF09133.5 ETO02819.1 - 0.044 13.7 0.0 0.086 12.8 0.0 1.5 1 0 0 1 1 1 0 SANTA (SANT Associated) Kinase-like PF14531.1 ETO02819.1 - 0.052 12.4 0.4 0.72 8.7 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Fork_head PF00250.13 ETO02819.1 - 0.085 12.9 5.0 0.17 11.9 0.6 2.6 1 1 1 2 2 2 0 Fork head domain Zn_ribbon_recom PF13408.1 ETO02819.1 - 0.29 11.4 2.8 0.76 10.0 1.9 1.7 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Mem_trans PF03547.13 ETO02819.1 - 2.9 6.0 4.7 3.1 5.9 3.3 1.2 1 0 0 1 1 1 0 Membrane transport protein Ndc1_Nup PF09531.5 ETO02819.1 - 3 6.1 9.9 2.9 6.2 6.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOBP PF15279.1 ETO02819.1 - 7.9 6.7 10.8 10 6.4 7.5 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Reprolysin_4 PF13583.1 ETO02821.1 - 0.1 12.0 0.3 0.11 12.0 0.2 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like XFP_C PF09363.5 ETO02822.1 - 0.014 14.8 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 XFP C-terminal domain WD40 PF00400.27 ETO02823.1 - 1.8e-12 46.5 0.3 5e-12 45.2 0.1 1.8 2 0 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO02823.1 - 0.00023 19.4 0.3 0.00038 18.7 0.1 1.4 1 1 0 1 1 1 1 Nucleoporin Nup120/160 TMF_DNA_bd PF12329.3 ETO02823.1 - 0.0011 18.6 20.7 0.002 17.9 14.4 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding Spc7 PF08317.6 ETO02823.1 - 0.0031 16.2 12.0 0.0035 16.0 8.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Vfa1 PF08432.5 ETO02823.1 - 0.005 16.8 11.1 0.007 16.4 7.7 1.1 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 PEARLI-4 PF05278.7 ETO02823.1 - 0.0074 15.6 8.0 0.0085 15.4 5.5 1.2 1 0 0 1 1 1 1 Arabidopsis phospholipase-like protein (PEARLI 4) DUF4337 PF14235.1 ETO02823.1 - 0.011 15.5 6.9 0.014 15.2 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF4055 PF13264.1 ETO02823.1 - 0.013 15.5 0.9 0.017 15.2 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) Phage_GP20 PF06810.6 ETO02823.1 - 0.027 13.9 14.2 0.039 13.3 9.9 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 GrpE PF01025.14 ETO02823.1 - 0.036 13.6 8.1 0.045 13.2 5.6 1.1 1 0 0 1 1 1 0 GrpE V_ATPase_I PF01496.14 ETO02823.1 - 0.04 11.8 4.8 0.037 11.8 3.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TRAP-gamma PF07074.7 ETO02823.1 - 0.061 12.8 3.2 0.08 12.4 2.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) DDHD PF02862.12 ETO02823.1 - 0.063 13.0 4.0 0.092 12.5 2.8 1.2 1 0 0 1 1 1 0 DDHD domain Atg14 PF10186.4 ETO02823.1 - 0.064 12.1 9.6 0.08 11.8 6.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 GCD14 PF08704.5 ETO02823.1 - 0.069 12.6 3.8 0.086 12.3 2.6 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit OmpH PF03938.9 ETO02823.1 - 0.078 12.9 12.2 0.1 12.5 8.5 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3552 PF12072.3 ETO02823.1 - 0.092 11.9 13.6 0.11 11.6 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF4200 PF13863.1 ETO02823.1 - 0.099 12.5 16.8 0.15 12.0 11.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) RNA_pol_Rpb1_5 PF04998.12 ETO02823.1 - 0.15 11.2 7.7 0.18 11.0 5.3 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF2203 PF09969.4 ETO02823.1 - 0.25 11.5 4.3 0.43 10.8 3.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) ATG16 PF08614.6 ETO02823.1 - 0.26 11.0 13.4 0.37 10.5 9.3 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) APG6 PF04111.7 ETO02823.1 - 0.29 10.1 9.9 0.36 9.8 6.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 ETO02823.1 - 0.29 10.8 16.3 0.37 10.5 11.3 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 ETO02823.1 - 0.32 10.5 9.4 0.41 10.2 6.5 1.1 1 0 0 1 1 1 0 IncA protein FemAB PF02388.11 ETO02823.1 - 0.65 8.6 11.0 0.77 8.3 7.6 1.1 1 0 0 1 1 1 0 FemAB family DUF3807 PF12720.2 ETO02823.1 - 1.1 9.4 10.2 0.47 10.5 5.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) TALPID3 PF15324.1 ETO02823.1 - 1.6 5.9 8.7 1.8 5.8 6.0 1.0 1 0 0 1 1 1 0 Hedgehog signalling target DUF106 PF01956.11 ETO02823.1 - 2.2 7.8 5.3 2.6 7.5 3.7 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF724 PF05266.9 ETO02823.1 - 2.4 7.7 13.5 3.2 7.3 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF972 PF06156.8 ETO02823.1 - 2.5 8.4 10.4 4.2 7.7 7.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF4407 PF14362.1 ETO02823.1 - 5.5 5.8 6.2 7.5 5.4 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HEAT_2 PF13646.1 ETO02824.1 - 8.6e-08 32.3 0.0 0.001 19.2 0.0 2.3 2 0 0 2 2 2 2 HEAT repeats HEAT PF02985.17 ETO02824.1 - 6.9e-06 25.7 0.0 0.00025 20.8 0.0 3.4 3 0 0 3 3 3 1 HEAT repeat DUF3137 PF11335.3 ETO02824.1 - 0.0018 17.9 0.1 0.005 16.5 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3137) HEAT_EZ PF13513.1 ETO02824.1 - 0.021 15.3 0.0 3.5 8.2 0.0 3.3 3 1 1 4 4 4 0 HEAT-like repeat Vac14_Fab1_bd PF12755.2 ETO02824.1 - 0.037 14.4 0.2 1.8 8.9 0.0 3.1 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region DUF3944 PF13099.1 ETO02824.1 - 0.29 10.6 3.0 1.8 8.1 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF3944) RPT PF13446.1 ETO02824.1 - 0.53 9.7 5.8 1.1 8.7 0.1 3.2 2 2 1 3 3 3 0 A repeated domain in UCH-protein DUF4569 PF15133.1 ETO02825.1 - 0.011 15.1 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) FragX_IP PF05994.6 ETO02827.1 - 0.00073 17.4 0.3 0.00088 17.2 0.2 1.0 1 0 0 1 1 1 1 Cytoplasmic Fragile-X interacting family M16C_assoc PF08367.6 ETO02827.1 - 0.022 13.6 0.1 0.027 13.3 0.1 1.1 1 0 0 1 1 1 0 Peptidase M16C associated RNA_pol_Rpb4 PF03874.11 ETO02827.1 - 0.048 13.6 2.1 0.053 13.5 1.5 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb4 DUF2228 PF10228.4 ETO02827.1 - 0.06 12.8 0.2 0.066 12.7 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) DUF2874 PF11396.3 ETO02827.1 - 0.1 12.5 0.2 0.19 11.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2874) DUF1002 PF06207.6 ETO02827.1 - 0.19 11.0 1.1 0.19 10.9 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) CLTH PF10607.4 ETO02827.1 - 1.5 8.5 5.4 2.3 7.9 3.7 1.3 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain RED_C PF07807.6 ETO02828.1 - 0.0016 18.5 1.9 0.0023 18.1 1.3 1.2 1 0 0 1 1 1 1 RED-like protein C-terminal region DUF4097 PF13349.1 ETO02831.1 - 0.018 14.5 0.1 0.035 13.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) GPS PF01825.16 ETO02831.1 - 6 7.0 10.1 0.39 10.8 1.1 2.6 2 0 0 2 2 2 0 Latrophilin/CL-1-like GPS domain NIR_SIR PF01077.17 ETO02832.1 - 0.093 12.0 0.1 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain Helicase_C PF00271.26 ETO02833.1 - 0.00035 20.3 0.2 0.0029 17.4 0.1 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain CutC PF03932.9 ETO02833.1 - 0.03 13.5 0.3 0.14 11.3 0.1 2.0 2 0 0 2 2 2 0 CutC family MHCassoc_trimer PF08831.5 ETO02833.1 - 0.071 12.9 0.2 1.3 8.9 0.1 2.9 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain Cut8_M PF14483.1 ETO02833.1 - 0.25 11.1 3.5 2.2 8.1 0.3 2.5 2 0 0 2 2 2 0 Cut8 dimerisation domain Ribonuc_L-PSP PF01042.16 ETO02833.1 - 0.43 10.3 4.8 1.4 8.6 0.2 3.2 2 1 1 3 3 3 0 Endoribonuclease L-PSP rve_2 PF13333.1 ETO02833.1 - 0.58 10.2 3.3 4.4 7.4 0.1 3.1 3 0 0 3 3 3 0 Integrase core domain UXS1_N PF11803.3 ETO02833.1 - 2 8.2 5.1 1.7 8.4 0.3 2.9 3 0 0 3 3 3 0 UDP-glucuronate decarboxylase N-terminal GalP_UDP_tr_C PF02744.12 ETO02834.1 - 0.073 12.6 0.2 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain PCP PF02429.10 ETO02834.1 - 0.11 12.5 0.2 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Peridinin-chlorophyll A binding protein DcpS_C PF11969.3 ETO02835.1 - 2.3e-09 37.4 0.2 6.3e-09 36.0 0.1 1.7 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 ETO02835.1 - 2.4e-08 34.4 0.1 6e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 HIT domain Chordopox_A35R PF05989.7 ETO02835.1 - 0.017 14.7 0.1 0.041 13.4 0.1 1.6 1 0 0 1 1 1 0 Chordopoxvirus A35R protein SMP_2 PF10144.4 ETO02836.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin zf-P11 PF03854.9 ETO02836.1 - 0.8 9.2 7.3 3.7 7.0 1.2 2.7 3 0 0 3 3 3 0 P-11 zinc finger zf-MIZ PF02891.15 ETO02836.1 - 5.2 6.6 9.9 0.49 9.9 1.7 3.0 2 1 0 3 3 3 0 MIZ/SP-RING zinc finger CENP-F_leu_zip PF10473.4 ETO02838.1 - 0.00032 20.5 25.6 0.026 14.3 8.6 2.5 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sugarporin_N PF11471.3 ETO02838.1 - 0.033 13.8 0.1 0.033 13.8 0.1 2.7 3 1 0 3 3 3 0 Maltoporin periplasmic N-terminal extension Mod_r PF07200.8 ETO02838.1 - 0.07 13.0 27.8 0.087 12.7 6.3 2.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Tropomyosin PF00261.15 ETO02838.1 - 0.11 11.5 21.3 46 2.9 14.8 2.3 1 1 0 1 1 1 0 Tropomyosin FlaC_arch PF05377.6 ETO02838.1 - 0.29 11.0 4.4 1.3 9.0 0.6 3.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) ADIP PF11559.3 ETO02838.1 - 0.3 10.9 38.4 1.3 8.8 12.0 2.9 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Laminin_II PF06009.7 ETO02838.1 - 0.42 10.3 14.2 0.024 14.4 4.1 2.3 1 1 1 2 2 2 0 Laminin Domain II APG6 PF04111.7 ETO02838.1 - 3 6.7 31.5 0.049 12.6 15.0 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 FtsL PF04999.8 ETO02838.1 - 7.4 6.3 10.3 5.4 6.8 1.9 2.9 2 2 1 3 3 3 0 Cell division protein FtsL GST_N_2 PF13409.1 ETO02839.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain HSP70 PF00012.15 ETO02840.1 - 0.00081 17.4 0.4 0.00082 17.4 0.3 1.0 1 0 0 1 1 1 1 Hsp70 protein Hydantoinase_A PF01968.13 ETO02840.1 - 0.032 13.3 0.0 0.034 13.2 0.0 1.1 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase EutA PF06277.6 ETO02840.1 - 0.04 12.5 0.0 0.04 12.5 0.0 1.0 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutA FtsA PF14450.1 ETO02840.1 - 0.058 13.2 0.1 0.096 12.5 0.1 1.3 1 1 0 1 1 1 0 Cell division protein FtsA DDR PF08841.5 ETO02840.1 - 0.13 11.0 0.2 0.18 10.6 0.1 1.3 1 1 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain BcrAD_BadFG PF01869.15 ETO02841.1 - 0.026 13.8 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family VirE PF05272.6 ETO02843.1 - 0.014 14.8 4.2 0.014 14.8 2.9 2.0 1 1 1 2 2 2 0 Virulence-associated protein E DUF4407 PF14362.1 ETO02843.1 - 0.066 12.1 17.3 0.096 11.6 12.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GIDA_assoc_3 PF13932.1 ETO02843.1 - 0.079 13.0 16.7 0.17 11.9 0.0 3.4 1 1 2 3 3 3 0 GidA associated domain 3 Reo_sigmaC PF04582.7 ETO02843.1 - 0.62 9.1 4.5 1.6 7.8 0.7 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF416 PF04222.7 ETO02843.1 - 0.87 8.6 26.1 0.24 10.5 6.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF416) TPR_MLP1_2 PF07926.7 ETO02843.1 - 1.1 9.0 44.1 0.92 9.2 11.5 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2935 PF11155.3 ETO02843.1 - 1.7 8.7 24.4 1.1 9.3 7.2 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF2935) HAUS6_N PF14661.1 ETO02843.1 - 2.9 7.2 31.6 8.8 5.6 15.6 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Seryl_tRNA_N PF02403.17 ETO02843.1 - 3.2 7.7 36.8 0.12 12.4 15.3 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF16 PF01519.11 ETO02843.1 - 3.5 7.9 41.4 2 8.6 10.3 2.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 Mannitol_dh PF01232.18 ETO02843.1 - 3.7 7.4 16.5 0.3 11.0 2.2 2.7 1 1 2 3 3 3 0 Mannitol dehydrogenase Rossmann domain zf-C4H2 PF10146.4 ETO02843.1 - 4.1 7.3 24.1 5.4 6.9 16.7 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein TMF_DNA_bd PF12329.3 ETO02843.1 - 4.2 7.2 46.3 0.13 12.1 7.2 4.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF1542 PF07564.6 ETO02843.1 - 4.8 7.2 29.0 0.065 13.2 6.3 3.1 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1542) ADIP PF11559.3 ETO02843.1 - 6.2 6.7 39.0 3.7 7.4 12.8 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2968 PF11180.3 ETO02843.1 - 7.4 5.9 28.2 0.27 10.5 7.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) APG6 PF04111.7 ETO02843.1 - 9.5 5.1 39.8 8.6 5.2 25.3 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF848 PF05852.6 ETO02843.1 - 9.6 6.0 28.2 15 5.4 11.1 2.4 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) CUE PF02845.11 ETO02844.1 - 0.00093 18.6 0.0 0.0034 16.8 0.0 2.0 2 0 0 2 2 2 1 CUE domain RelA_SpoT PF04607.12 ETO02844.1 - 0.013 15.5 0.2 0.013 15.5 0.1 2.6 3 0 0 3 3 3 0 Region found in RelA / SpoT proteins DUF1664 PF07889.7 ETO02844.1 - 0.09 12.5 3.0 0.25 11.1 2.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Sipho_Gp157 PF05565.6 ETO02844.1 - 6 6.4 19.1 3 7.4 6.2 2.9 2 1 1 3 3 3 0 Siphovirus Gp157 FAD_binding_2 PF00890.19 ETO02845.1 - 2.9e-27 95.5 0.3 3.2e-27 95.4 0.2 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETO02845.1 - 1.7e-08 33.7 0.1 2e-08 33.5 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 ETO02845.1 - 4.5e-08 32.5 0.1 4.6e-08 32.5 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETO02845.1 - 9.6e-06 25.5 1.6 9.6e-06 25.5 1.1 2.2 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 ETO02845.1 - 1.6e-05 23.9 0.3 1.8e-05 23.8 0.2 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 ETO02845.1 - 2.5e-05 24.2 0.1 2.8e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 ETO02845.1 - 6e-05 22.2 0.1 6.4e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 ETO02845.1 - 0.00011 21.3 0.1 0.00013 21.1 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 ETO02845.1 - 0.00019 21.5 0.2 0.00032 20.8 0.2 1.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETO02845.1 - 0.0002 19.9 2.2 0.00027 19.5 1.5 1.3 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 ETO02845.1 - 0.002 18.4 0.7 0.0036 17.6 0.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 ETO02845.1 - 0.005 16.5 0.2 0.0058 16.2 0.1 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 ETO02845.1 - 0.027 13.3 0.6 0.044 12.7 0.4 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 ETO02845.1 - 0.039 14.2 0.0 0.053 13.7 0.0 1.2 1 0 0 1 1 1 0 Putative NAD(P)-binding YcgL PF05166.8 ETO02846.1 - 0.2 11.7 1.3 0.38 10.9 0.1 1.9 2 0 0 2 2 2 0 YcgL domain Peptidase_C10 PF01640.12 ETO02846.1 - 0.29 10.8 5.0 0.35 10.6 3.4 1.1 1 0 0 1 1 1 0 Peptidase C10 family Plasmid_parti PF01672.11 ETO02846.1 - 2.2 8.7 6.8 0.95 9.9 0.8 2.5 1 1 0 2 2 2 0 Putative plasmid partition protein Zip PF02535.17 ETO02848.1 - 0.21 10.5 0.9 0.23 10.4 0.6 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter RHD3 PF05879.7 ETO02849.1 - 6.6e-17 60.7 0.1 6.6e-17 60.7 0.1 2.2 2 1 0 2 2 2 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 ETO02849.1 - 6e-11 41.9 0.1 6e-11 41.9 0.1 1.9 2 1 0 2 2 2 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 ETO02849.1 - 1.9e-05 24.6 0.0 7e-05 22.7 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 ETO02849.1 - 0.00018 21.9 0.7 0.00053 20.4 0.1 2.1 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 ETO02849.1 - 0.0025 17.6 0.1 0.0025 17.6 0.1 2.7 2 2 1 3 3 3 1 Dynamin family Arch_ATPase PF01637.13 ETO02849.1 - 0.004 16.8 0.1 0.004 16.8 0.1 2.5 2 1 0 2 2 2 1 Archaeal ATPase AAA_28 PF13521.1 ETO02849.1 - 0.0094 15.9 0.2 0.029 14.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 ETO02849.1 - 0.079 12.8 2.5 0.13 12.2 0.0 2.7 3 1 0 3 3 3 0 AAA domain OSCP PF00213.13 ETO02849.1 - 0.13 12.0 4.0 0.43 10.4 2.8 1.8 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit IL6 PF00489.12 ETO02849.1 - 0.14 11.7 0.2 0.14 11.7 0.1 2.4 2 0 0 2 2 2 0 Interleukin-6/G-CSF/MGF family ABC_tran PF00005.22 ETO02849.1 - 0.64 10.3 0.0 0.64 10.3 0.0 2.7 2 1 0 2 2 1 0 ABC transporter Gly-zipper_Omp PF13488.1 ETO02850.1 - 3.8e-09 36.0 139.7 1.2e+04 -4.0 9.2 8.4 1 1 1 2 2 2 0 Glycine zipper Gly-zipper_YMGG PF13441.1 ETO02850.1 - 9.8e-06 24.9 115.9 0.0021 17.4 3.2 8.2 1 1 4 5 5 5 3 YMGG-like Gly-zipper Bacteriocin_IIc PF10439.4 ETO02850.1 - 1.4 9.0 135.0 17 5.6 6.0 8.8 1 1 1 2 2 2 0 Bacteriocin class II with double-glycine leader peptide MMS19_C PF12460.3 ETO02852.1 - 0.047 12.4 0.5 0.067 11.9 0.4 1.1 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal POTRA_1 PF08478.5 ETO02854.1 - 0.13 12.3 0.1 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 POTRA domain, FtsQ-type Ly49 PF08391.5 ETO02858.1 - 3.6 7.7 8.9 1.9 8.6 0.1 2.8 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region DUF2573 PF10835.3 ETO02859.1 - 0.067 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2573) DUF1765 PF08578.5 ETO02862.1 - 0.011 15.7 2.0 3.8 7.6 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1765) Methyltransf_31 PF13847.1 ETO02863.1 - 4.8e-07 29.4 1.4 7.1e-07 28.9 0.3 1.7 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.9 ETO02863.1 - 6.3e-05 22.4 0.0 9.7e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 ETO02863.1 - 0.0017 18.3 0.0 0.0031 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO02863.1 - 0.018 15.6 0.0 0.06 13.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.13 ETO02863.1 - 0.02 14.0 0.2 0.15 11.1 0.0 1.9 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 ETO02863.1 - 0.04 12.9 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_25 PF13649.1 ETO02863.1 - 0.052 13.9 0.3 0.17 12.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Mannitol_dh_C PF08125.8 ETO02863.1 - 0.12 11.5 0.2 10 5.2 0.0 2.1 2 0 0 2 2 2 0 Mannitol dehydrogenase C-terminal domain Pox_MCEL PF03291.11 ETO02863.1 - 2.3 6.9 7.1 0.47 9.2 1.0 1.9 1 1 1 2 2 2 0 mRNA capping enzyme Methyltrn_RNA_3 PF02598.12 ETO02864.1 - 0.058 12.7 1.2 0.12 11.6 0.8 1.5 1 1 0 1 1 1 0 Putative RNA methyltransferase GHL6 PF14871.1 ETO02865.1 - 0.069 13.1 0.3 0.1 12.5 0.2 1.3 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Bromodomain PF00439.20 ETO02865.1 - 0.18 11.7 2.5 0.31 10.9 0.2 2.4 2 1 1 3 3 3 0 Bromodomain SAMP PF05924.6 ETO02867.1 - 0.059 12.5 0.4 0.14 11.3 0.3 1.6 1 0 0 1 1 1 0 SAMP Motif Bromodomain PF00439.20 ETO02868.1 - 2.9e-12 46.3 0.3 8.9e-12 44.7 0.0 2.0 1 1 1 2 2 2 1 Bromodomain Kelch_5 PF13854.1 ETO02869.1 - 0.0024 17.7 0.2 0.03 14.2 0.0 2.2 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETO02869.1 - 0.092 12.9 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Kelch motif Methyltransf_27 PF13708.1 ETO02870.1 - 0.18 11.3 0.8 0.92 9.0 0.1 1.9 2 0 0 2 2 2 0 Methyltransferase domain DUF914 PF06027.7 ETO02871.1 - 0.15 10.8 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) HSP33 PF01430.14 ETO02871.1 - 0.27 10.3 3.9 1.2 8.1 1.1 2.0 2 0 0 2 2 2 0 Hsp33 protein Kelch_1 PF01344.20 ETO02873.1 - 2.4e-05 23.7 0.4 0.00079 18.9 0.1 2.2 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.1 ETO02873.1 - 8.7e-05 22.2 0.3 0.044 13.5 0.0 2.2 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO02873.1 - 0.013 15.6 1.5 0.54 10.5 0.1 2.2 2 0 0 2 2 2 0 Kelch motif Kelch_5 PF13854.1 ETO02873.1 - 0.041 13.8 2.9 0.23 11.4 0.2 2.2 2 0 0 2 2 2 0 Kelch motif WD40 PF00400.27 ETO02874.1 - 1.8e-19 68.7 11.0 1.5e-10 40.5 1.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO02874.1 - 0.00013 20.2 2.4 0.00087 17.5 0.2 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Dala_Dala_lig_C PF07478.8 ETO02874.1 - 0.14 11.4 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus TPR_12 PF13424.1 ETO02875.1 - 7.4e-37 125.1 10.5 9.3e-21 73.5 0.9 2.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO02875.1 - 6.6e-21 73.5 0.0 9.4e-07 28.5 0.0 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO02875.1 - 5.5e-15 54.7 12.6 1.8e-10 40.3 1.9 2.4 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 ETO02875.1 - 5.6e-13 47.7 9.0 6.5e-06 25.6 0.3 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO02875.1 - 7.5e-12 44.3 15.0 2.3e-06 26.9 0.8 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO02875.1 - 5.1e-07 29.0 1.0 0.0099 15.6 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO02875.1 - 1.6e-06 27.4 17.3 0.011 15.4 0.8 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO02875.1 - 2.8e-05 24.6 0.0 0.00098 19.7 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat SNAP PF14938.1 ETO02875.1 - 7.7e-05 21.9 0.9 9.4e-05 21.6 0.6 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.1 ETO02875.1 - 0.0011 19.2 2.3 3.1 8.4 0.1 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO02875.1 - 0.0013 18.7 0.9 1.1 9.6 0.3 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO02875.1 - 0.0028 16.8 0.0 0.8 8.9 0.0 3.0 3 0 0 3 3 3 1 SHNi-TPR DUF2225 PF09986.4 ETO02875.1 - 0.0076 15.7 3.1 0.011 15.1 2.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) Inhibitor_I29 PF08246.7 ETO02875.1 - 0.0093 16.2 6.3 1.7 8.9 0.4 3.0 3 0 0 3 3 3 2 Cathepsin propeptide inhibitor domain (I29) DUF627 PF04781.7 ETO02875.1 - 0.071 12.7 3.9 1.1 8.9 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF627) Apc3 PF12895.2 ETO02875.1 - 0.18 11.9 9.1 2.5 8.3 0.4 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 VirDNA-topo-I_N PF09266.5 ETO02875.1 - 0.44 10.4 4.4 13 5.7 0.0 3.1 3 0 0 3 3 3 0 Viral DNA topoisomerase I, N-terminal NSF PF02071.15 ETO02875.1 - 2 9.3 4.1 1e+02 4.2 1.2 3.1 2 0 0 2 2 2 0 Aromatic-di-Alanine (AdAR) repeat TPR_3 PF07720.7 ETO02875.1 - 7.4 6.4 14.2 2.1 8.2 0.7 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat PAZ PF02170.17 ETO02875.1 - 7.8 5.8 13.9 4.6 6.5 0.1 3.1 3 0 0 3 3 3 0 PAZ domain ARID PF01388.16 ETO02876.1 - 0.0043 16.8 0.2 0.0072 16.1 0.1 1.4 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Sigma70_ner PF04546.8 ETO02876.1 - 0.005 16.4 2.4 0.0073 15.9 1.4 1.4 1 1 0 1 1 1 1 Sigma-70, non-essential region RXT2_N PF08595.6 ETO02876.1 - 0.074 12.8 7.2 0.12 12.2 5.0 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal CobT PF06213.7 ETO02876.1 - 1 8.4 7.5 1.4 7.9 5.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PBP1_TM PF14812.1 ETO02876.1 - 3.4 8.0 11.5 0.16 12.2 3.2 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.7 ETO02876.1 - 7.8 5.6 8.3 9.7 5.3 5.8 1.2 1 0 0 1 1 1 0 NOA36 protein ARID PF01388.16 ETO02877.1 - 0.0042 16.9 0.2 0.0072 16.1 0.1 1.4 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Sigma70_ner PF04546.8 ETO02877.1 - 0.023 14.3 2.0 0.031 13.8 1.1 1.4 1 1 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.6 ETO02877.1 - 0.12 12.1 6.5 0.2 11.4 4.5 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.7 ETO02877.1 - 2.8 7.1 7.2 3.4 6.8 5.0 1.2 1 0 0 1 1 1 0 NOA36 protein DUF4376 PF14301.1 ETO02878.1 - 0.057 13.5 0.5 0.1 12.7 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4376) Ribosomal_S17e PF00833.13 ETO02885.1 - 0.026 14.2 0.7 0.097 12.4 0.2 1.9 2 0 0 2 2 2 0 Ribosomal S17 DUF3222 PF11519.3 ETO02887.1 - 0.091 12.7 0.6 0.13 12.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3222) 2OG-Fe_Oxy_2 PF10014.4 ETO02887.1 - 2.5 7.4 6.3 4.8 6.5 4.4 1.6 1 1 0 1 1 1 0 2OG-Fe dioxygenase Endotoxin_N PF03945.9 ETO02888.1 - 0.0085 15.5 0.3 0.0085 15.5 0.2 1.6 2 0 0 2 2 2 1 delta endotoxin, N-terminal domain DUF4211 PF13926.1 ETO02889.1 - 0.0089 15.4 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) HEAT_2 PF13646.1 ETO02890.1 - 1.3e-18 67.0 0.0 0.00011 22.3 0.0 6.0 5 1 1 6 6 5 3 HEAT repeats HEAT PF02985.17 ETO02890.1 - 2.6e-11 42.6 0.1 0.082 13.0 0.0 7.5 8 0 0 8 8 7 2 HEAT repeat HEAT_EZ PF13513.1 ETO02890.1 - 5e-10 39.5 0.0 0.0081 16.6 0.0 6.4 6 1 1 7 7 7 2 HEAT-like repeat Ank_2 PF12796.2 ETO02890.1 - 2.3e-09 37.4 1.1 8e-09 35.7 0.4 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) CLASP_N PF12348.3 ETO02890.1 - 9.1e-09 34.9 3.8 0.015 14.6 0.1 4.6 3 1 1 4 4 4 2 CLASP N terminal Ank_3 PF13606.1 ETO02890.1 - 3e-08 33.1 0.2 0.0024 17.9 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.25 ETO02890.1 - 3.3e-08 32.9 0.1 1e-05 25.1 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 ETO02890.1 - 2.7e-07 30.9 0.2 1.4e-06 28.6 0.2 2.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO02890.1 - 3.6e-06 27.0 0.1 8.8e-05 22.6 0.1 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) DUF3554 PF12074.3 ETO02890.1 - 4.4e-05 23.0 3.0 0.11 11.9 0.0 3.7 3 1 1 4 4 4 2 Domain of unknown function (DUF3554) DUF3368 PF11848.3 ETO02890.1 - 0.035 13.6 0.1 15 5.2 0.0 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) RNA_binding PF01877.12 ETO02890.1 - 4.1 7.4 12.5 1.1 9.2 0.2 5.2 4 3 4 8 8 8 0 RNA binding Mlp PF03304.8 ETO02891.1 - 0.0022 18.0 5.1 0.0036 17.3 3.6 1.4 1 0 0 1 1 1 1 Mlp lipoprotein family Peptidase_M44 PF03410.8 ETO02891.1 - 0.015 13.6 0.2 0.085 11.1 0.1 1.8 1 1 1 2 2 2 0 Protein G1 MA3 PF02847.12 ETO02891.1 - 0.047 13.3 1.3 2.8 7.6 0.1 2.3 2 0 0 2 2 2 0 MA3 domain PUB PF09409.5 ETO02891.1 - 0.098 12.4 3.4 0.15 11.8 0.5 2.7 2 2 0 2 2 2 0 PUB domain DUF3066 PF11266.3 ETO02892.1 - 0.0042 16.8 1.2 0.0042 16.8 0.8 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3066) DUF2110 PF09883.4 ETO02892.1 - 0.014 15.0 0.5 0.028 14.0 0.1 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2110) SecD-TM1 PF13721.1 ETO02892.1 - 0.073 13.3 0.7 0.15 12.3 0.2 1.6 1 1 0 1 1 1 0 SecD export protein N-terminal TM region TINF2_N PF14973.1 ETO02892.1 - 0.089 12.9 4.1 0.22 11.6 2.8 1.7 1 1 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus DUF1878 PF08963.5 ETO02892.1 - 0.1 12.8 1.5 0.12 12.6 0.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1878) S-AdoMet_synt_M PF02772.11 ETO02892.1 - 0.19 11.6 1.1 0.31 11.0 0.8 1.4 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, central domain CHASE3 PF05227.8 ETO02892.1 - 0.19 11.4 3.5 0.16 11.6 0.4 1.9 1 1 1 2 2 2 0 CHASE3 domain Chalcone PF02431.10 ETO02892.1 - 3.8 6.8 8.0 9.1 5.6 3.6 2.0 1 1 1 2 2 2 0 Chalcone-flavanone isomerase Phospholip_B PF04916.8 ETO02893.1 - 0.033 12.3 0.1 0.041 11.9 0.0 1.1 1 0 0 1 1 1 0 Phospholipase B ParBc_2 PF08857.6 ETO02893.1 - 0.04 13.7 0.3 0.052 13.3 0.2 1.3 1 1 0 1 1 1 0 Putative ParB-like nuclease PRA1 PF03208.14 ETO02894.1 - 1.2 8.4 9.8 0.22 10.8 4.2 1.7 1 1 1 2 2 2 0 PRA1 family protein zf-TRAF PF02176.13 ETO02895.1 - 1.6e-07 31.5 2.0 1.6e-07 31.5 1.4 2.6 3 0 0 3 3 3 1 TRAF-type zinc finger P53_C PF11619.3 ETO02895.1 - 0.14 11.9 0.1 0.39 10.5 0.1 1.8 1 0 0 1 1 1 0 Transcription factor P53 - C terminal domain Fer4_6 PF12837.2 ETO02895.1 - 2.3 8.2 6.0 3.1 7.8 0.6 3.0 3 0 0 3 3 3 0 4Fe-4S binding domain DUF1312 PF07009.6 ETO02896.1 - 0.15 11.8 4.6 0.19 11.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1312) Clr5 PF14420.1 ETO02897.1 - 0.12 12.2 0.6 0.23 11.3 0.4 1.4 1 0 0 1 1 1 0 Clr5 domain HSBP1 PF06825.7 ETO02898.1 - 0.025 14.1 4.4 0.025 14.1 3.0 3.1 4 0 0 4 4 4 0 Heat shock factor binding protein 1 OmpH PF03938.9 ETO02898.1 - 0.56 10.1 19.9 1.9 8.4 3.2 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF2317 PF10079.4 ETO02898.1 - 1.3 7.5 14.3 0.29 9.6 7.0 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2317) Tweety PF04906.8 ETO02898.1 - 2.3 6.5 11.2 1.1 7.6 3.5 2.2 1 1 2 3 3 3 0 Tweety Fzo_mitofusin PF04799.8 ETO02898.1 - 4.7 6.5 17.2 0.048 13.0 4.0 2.6 1 1 1 3 3 3 0 fzo-like conserved region KxDL PF10241.4 ETO02901.1 - 0.042 13.7 1.8 0.073 12.9 1.2 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein Vfa1 PF08432.5 ETO02901.1 - 0.25 11.3 11.5 0.36 10.8 7.9 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FAM176 PF14851.1 ETO02901.1 - 3.3 7.3 13.3 7.3 6.2 9.2 1.6 1 1 0 1 1 1 0 FAM176 family CDC45 PF02724.9 ETO02901.1 - 7.9 4.3 14.7 8.6 4.2 10.2 1.1 1 0 0 1 1 1 0 CDC45-like protein GRP PF07172.6 ETO02902.1 - 0.13 12.7 10.4 0.14 12.6 7.2 1.2 1 0 0 1 1 1 0 Glycine rich protein family DUF2491 PF10679.4 ETO02904.1 - 0.029 13.3 0.4 0.035 13.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) PAP_central PF04928.12 ETO02904.1 - 0.066 12.0 0.1 0.1 11.3 0.0 1.4 1 0 0 1 1 1 0 Poly(A) polymerase central domain ORF6C PF10552.4 ETO02904.1 - 0.08 12.6 0.7 0.19 11.4 0.1 1.9 1 1 1 2 2 2 0 ORF6C domain UCH PF00443.24 ETO02906.1 - 1.9e-23 82.9 0.0 4.6e-23 81.6 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO02906.1 - 5.8e-16 58.7 0.0 6.5e-10 38.9 0.0 2.1 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PTR2 PF00854.16 ETO02908.1 - 7.9e-23 80.8 6.4 1.4e-22 80.0 4.5 1.4 1 1 0 1 1 1 1 POT family Rod_cone_degen PF15201.1 ETO02908.1 - 0.019 14.7 4.0 0.036 13.9 1.3 2.2 1 1 1 2 2 2 0 Progressive rod-cone degeneration CTP_transf_1 PF01148.15 ETO02909.1 - 1.7e-61 208.1 16.5 2.4e-61 207.6 11.5 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Utp14 PF04615.8 ETO02909.1 - 0.05 11.7 8.2 0.066 11.3 5.7 1.0 1 0 0 1 1 1 0 Utp14 protein Nop53 PF07767.6 ETO02909.1 - 0.13 11.1 9.2 0.18 10.7 6.4 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CBS PF00571.23 ETO02910.1 - 1.5e-27 95.0 0.1 6.7e-08 32.1 0.0 4.3 4 0 0 4 4 4 4 CBS domain NPR3 PF03666.8 ETO02912.1 - 0.024 13.1 0.0 0.024 13.1 0.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Cas_Cmr5 PF09701.5 ETO02913.1 - 0.1 12.7 0.2 13 5.9 0.0 2.1 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Cmr5) DUF912 PF06024.7 ETO02913.1 - 0.26 11.3 1.5 0.38 10.8 1.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) WD40 PF00400.27 ETO02914.1 - 2.8e-19 68.1 7.3 2.5e-06 27.1 0.1 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat WD40 PF00400.27 ETO02915.1 - 4.9e-31 105.4 11.4 3.4e-06 26.7 0.1 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_3 PF13570.1 ETO02915.1 - 0.19 12.0 1.6 37 4.7 0.0 3.5 3 1 0 3 3 3 0 PQQ-like domain TPR_12 PF13424.1 ETO02917.1 - 6.1e-91 298.4 21.8 6.4e-24 83.7 2.2 6.6 2 2 5 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.1 ETO02917.1 - 3.5e-43 144.3 0.0 6.7e-07 29.0 0.0 8.1 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETO02917.1 - 7.8e-42 139.2 33.5 3.7e-08 32.6 0.4 8.7 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.1 ETO02917.1 - 1.9e-38 129.9 21.9 2.1e-13 49.6 1.1 6.1 4 1 3 7 7 7 6 TPR repeat TPR_2 PF07719.12 ETO02917.1 - 1.9e-36 121.0 23.0 2.1e-05 24.0 0.2 8.6 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_7 PF13176.1 ETO02917.1 - 1.4e-34 115.1 11.9 1.4e-05 24.4 0.0 8.3 8 1 1 9 9 8 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETO02917.1 - 4.5e-27 91.7 45.6 8e-06 25.2 0.8 8.5 9 0 0 9 9 8 7 Tetratricopeptide repeat TPR_17 PF13431.1 ETO02917.1 - 1e-12 47.1 12.5 0.003 17.6 0.1 7.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO02917.1 - 2.6e-11 43.8 0.0 0.0057 17.3 0.1 5.7 4 2 3 7 7 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO02917.1 - 8.2e-10 38.4 0.0 1.7 9.4 0.0 6.9 6 1 1 7 7 7 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO02917.1 - 1.6e-07 31.3 19.0 0.0036 17.3 4.2 5.0 2 1 4 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETO02917.1 - 2.1e-07 30.9 7.6 8.9 7.0 0.0 7.3 8 0 0 8 8 7 0 Tetratricopeptide repeat DUF627 PF04781.7 ETO02917.1 - 1.3e-06 27.9 9.6 0.0027 17.3 0.0 4.9 2 2 3 5 5 5 1 Protein of unknown function (DUF627) TPR_19 PF14559.1 ETO02917.1 - 3.9e-06 27.1 4.6 0.22 11.9 0.5 5.2 4 1 3 7 7 6 2 Tetratricopeptide repeat MIT PF04212.13 ETO02917.1 - 8.6e-05 22.3 24.4 0.14 12.0 0.1 6.9 7 0 0 7 7 7 1 MIT (microtubule interacting and transport) domain Sel1 PF08238.7 ETO02917.1 - 0.0029 18.2 10.5 2.4 8.9 0.0 6.4 6 1 0 6 6 6 1 Sel1 repeat SHNi-TPR PF10516.4 ETO02917.1 - 0.003 16.7 11.0 6.1 6.1 0.0 7.2 8 0 0 8 8 8 0 SHNi-TPR TPR_3 PF07720.7 ETO02917.1 - 0.0045 16.7 21.2 0.036 13.8 1.1 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO02917.1 - 0.0068 16.2 16.4 4 7.3 0.0 6.5 7 0 0 7 7 7 1 Fis1 C-terminal tetratricopeptide repeat DUF2977 PF11192.3 ETO02917.1 - 0.011 15.5 1.9 29 4.6 0.0 4.0 4 0 0 4 4 3 0 Protein of unknown function (DUF2977) Mob_Pre PF01076.14 ETO02917.1 - 0.023 14.3 0.1 0.023 14.3 0.1 3.9 2 1 2 4 4 4 0 Plasmid recombination enzyme HisG PF01634.13 ETO02917.1 - 0.023 14.2 0.6 4.5 6.8 0.0 2.9 1 1 2 3 3 3 0 ATP phosphoribosyltransferase Ten1_2 PF15490.1 ETO02917.1 - 0.04 13.4 0.2 41 3.7 0.0 4.0 1 1 4 5 5 5 0 Telomere-capping, CST complex subunit PY_rept_46 PF09689.5 ETO02917.1 - 0.085 13.2 2.6 0.42 10.9 0.4 3.1 2 0 0 2 2 2 0 Plasmodium yoelii repeat (PY_rept_46) PPR PF01535.15 ETO02917.1 - 0.17 11.9 9.1 8.4 6.6 0.1 6.1 6 0 0 6 6 6 0 PPR repeat DUF1955 PF09205.5 ETO02917.1 - 0.24 10.8 4.5 0.37 10.3 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1955) DUF386 PF04074.7 ETO02917.1 - 0.38 10.2 7.3 0.34 10.4 2.9 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF386) DUF87 PF01935.12 ETO02917.1 - 1.6 8.4 10.2 1 9.0 2.5 2.4 1 1 1 2 2 2 0 Domain of unknown function DUF87 Gly-zipper_Omp PF13488.1 ETO02918.1 - 5.6e-16 57.9 28.8 0.0011 18.6 4.0 5.5 1 1 2 3 3 3 3 Glycine zipper Gly-zipper_YMGG PF13441.1 ETO02918.1 - 3.9e-11 42.2 15.8 0.01 15.3 0.8 5.3 1 1 1 2 2 2 2 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.10 ETO02918.1 - 2.2e-05 24.0 44.3 0.013 15.1 2.0 6.9 3 2 2 5 5 5 4 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 ETO02918.1 - 5.8e-05 22.7 23.2 0.3 10.7 1.0 4.3 1 1 3 4 4 4 4 Glycine-zipper containing OmpA-like membrane domain DUF456 PF04306.8 ETO02918.1 - 0.00032 20.7 62.2 0.35 10.9 2.2 5.0 1 1 1 2 2 2 1 Protein of unknown function (DUF456) TraT PF05818.7 ETO02918.1 - 0.012 15.0 15.9 6.4 6.1 1.7 3.6 1 1 1 2 2 2 0 Enterobacterial TraT complement resistance protein Bacteriocin_IIc PF10439.4 ETO02918.1 - 0.021 14.9 60.8 5.2e+03 -2.4 15.7 5.7 1 1 1 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Transgly_assoc PF04226.8 ETO02918.1 - 3.3 7.8 57.1 1.2 9.2 7.6 5.9 1 1 3 4 4 4 0 Transglycosylase associated protein Glycogen_syn PF05693.8 ETO02919.1 - 0.013 13.8 0.1 0.013 13.8 0.1 1.1 1 0 0 1 1 1 0 Glycogen synthase COQ7 PF03232.8 ETO02919.1 - 0.035 13.5 2.3 0.045 13.2 1.6 1.5 1 1 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 Ank_3 PF13606.1 ETO02920.1 - 0.0001 22.1 0.1 0.059 13.6 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeat ASFV_p27 PF06556.6 ETO02920.1 - 0.057 13.3 0.3 0.12 12.2 0.2 1.6 1 0 0 1 1 1 0 IAP-like protein p27 C-terminus Ank_4 PF13637.1 ETO02920.1 - 0.089 13.3 0.1 7.2 7.2 0.0 2.7 2 1 0 2 2 2 0 Ankyrin repeats (many copies) WD40 PF00400.27 ETO02921.1 - 2.3e-28 96.9 12.1 1.5e-11 43.6 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO02921.1 - 2.2e-06 26.1 2.4 4.4e-05 21.8 1.5 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 HEAT PF02985.17 ETO02922.1 - 1.1e-12 46.8 0.1 0.087 12.9 0.0 7.6 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 ETO02922.1 - 2.2e-12 47.0 0.0 0.021 15.0 0.0 5.2 4 2 2 6 6 6 3 HEAT repeats HEAT_EZ PF13513.1 ETO02922.1 - 5e-07 30.0 0.0 0.31 11.5 0.0 6.0 5 2 1 6 6 6 1 HEAT-like repeat Cnd1 PF12717.2 ETO02922.1 - 1.5e-06 28.2 20.9 0.024 14.5 2.6 5.3 3 2 1 4 4 4 4 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 ETO02922.1 - 0.00015 21.5 2.8 2.8 7.8 0.1 5.1 4 1 0 4 4 4 2 Protein of unknown function (DUF2435) DUF2431 PF10354.4 ETO02923.1 - 4e-10 39.9 5.3 0.00024 21.0 0.0 3.8 2 1 1 3 3 3 2 Domain of unknown function (DUF2431) La PF05383.12 ETO02924.1 - 0.00077 19.2 1.4 0.0011 18.6 1.0 1.3 1 0 0 1 1 1 1 La domain GAGA_bind PF06217.7 ETO02924.1 - 1.1 9.2 17.5 1.1 9.1 12.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3513 PF12026.3 ETO02924.1 - 1.3 8.4 11.5 1.7 8.1 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) HEPPP_synt_1 PF07307.6 ETO02924.1 - 1.6 8.0 8.9 2.2 7.6 6.2 1.2 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 DUF3807 PF12720.2 ETO02924.1 - 2.3 8.3 14.2 2.5 8.2 9.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Pol_alpha_B_N PF08418.5 ETO02924.1 - 2.6 7.4 13.1 3.4 7.1 9.1 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal GCD14 PF08704.5 ETO02924.1 - 2.9 7.3 8.2 3.3 7.1 5.7 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Band_3_cyto PF07565.8 ETO02924.1 - 3.9 6.9 6.5 3.9 6.9 4.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain AbiH PF14253.1 ETO02924.1 - 4.9 6.6 13.6 5.4 6.5 9.5 1.0 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH Peptidase_S49_N PF08496.5 ETO02924.1 - 5 6.8 20.6 6.7 6.4 14.3 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Neur_chan_memb PF02932.11 ETO02924.1 - 6.8 6.4 6.7 7.1 6.4 4.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4604 PF15377.1 ETO02924.1 - 7.4 6.7 23.5 10 6.2 16.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) P5-ATPase PF12409.3 ETO02924.1 - 7.5 6.4 11.0 27 4.6 7.6 1.8 1 1 0 1 1 1 0 P5-type ATPase cation transporter DDHD PF02862.12 ETO02924.1 - 8.5 6.1 9.0 9.1 5.9 6.2 1.1 1 0 0 1 1 1 0 DDHD domain YqfQ PF14181.1 ETO02924.1 - 8.8 6.3 16.1 12 5.8 11.2 1.2 1 0 0 1 1 1 0 YqfQ-like protein Kelch_6 PF13964.1 ETO02925.1 - 0.00025 21.0 4.3 0.62 10.3 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO02925.1 - 0.00037 19.9 0.6 0.98 9.0 0.1 3.5 3 0 0 3 3 3 2 Kelch motif Glyoxal_oxid_N PF07250.6 ETO02925.1 - 0.0022 17.1 0.2 0.018 14.1 0.0 2.1 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus Kelch_5 PF13854.1 ETO02925.1 - 0.014 15.3 0.7 0.14 12.1 0.0 3.0 3 0 0 3 3 3 0 Kelch motif DFF40 PF09230.5 ETO02926.1 - 0.029 13.7 0.7 0.047 13.0 0.5 1.4 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa KAP_NTPase PF07693.9 ETO02926.1 - 0.036 13.0 0.2 0.04 12.9 0.2 1.2 1 0 0 1 1 1 0 KAP family P-loop domain PUB PF09409.5 ETO02926.1 - 2.3 8.0 7.2 0.18 11.5 0.4 2.6 3 1 0 3 3 3 0 PUB domain ERAP1_C PF11838.3 ETO02927.1 - 5.6e-13 48.8 0.1 6.6e-13 48.5 0.1 1.0 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Rax2 PF12768.2 ETO02928.1 - 0.073 12.2 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity PIP49_N PF14875.1 ETO02929.1 - 0.0091 15.6 0.8 0.0091 15.6 0.6 1.7 2 0 0 2 2 2 1 N-term cysteine-rich ER, FAM69 Podoplanin PF05808.6 ETO02929.1 - 0.92 9.0 3.7 1.6 8.2 2.6 1.3 1 1 0 1 1 1 0 Podoplanin HDNR PF15115.1 ETO02930.1 - 0.12 12.3 0.0 0.52 10.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function with conserved HDNR motif DnaJ PF00226.26 ETO02931.1 - 1.3e-22 79.2 1.2 1.3e-22 79.2 0.8 1.8 2 0 0 2 2 2 1 DnaJ domain CTDII PF01556.13 ETO02931.1 - 0.00016 21.4 0.1 0.0032 17.3 0.0 2.8 2 1 0 2 2 2 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 ETO02931.1 - 0.017 15.1 17.7 0.076 13.0 9.0 2.6 2 0 0 2 2 2 0 DnaJ central domain DUF3605 PF12239.3 ETO02931.1 - 0.072 12.9 0.4 0.16 11.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3605) DUF3092 PF11289.3 ETO02934.1 - 0.14 11.3 4.5 0.19 10.8 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3092) PLRV_ORF5 PF01690.12 ETO02934.1 - 2.2 7.3 15.1 0.17 10.9 7.1 1.4 2 0 0 2 2 2 0 Potato leaf roll virus readthrough protein Neur_chan_memb PF02932.11 ETO02934.1 - 8.5 6.1 13.5 0.051 13.4 2.9 2.0 2 1 1 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region HEAT_2 PF13646.1 ETO02935.1 - 1.2e-06 28.7 0.0 2.2e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 HEAT repeats HEAT PF02985.17 ETO02935.1 - 7.4e-06 25.6 0.0 0.036 14.1 0.0 3.2 3 0 0 3 3 3 2 HEAT repeat NLE PF08154.7 ETO02935.1 - 4.7e-05 23.3 0.9 1.5 8.9 0.0 3.8 2 1 2 4 4 4 2 NLE (NUC135) domain Vac14_Fab1_bd PF12755.2 ETO02935.1 - 0.00017 21.9 0.1 0.00057 20.2 0.0 1.9 1 1 0 1 1 1 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 ETO02935.1 - 0.00099 19.5 0.1 0.0047 17.3 0.0 2.2 3 0 0 3 3 3 1 HEAT-like repeat DUF3554 PF12074.3 ETO02935.1 - 0.0035 16.8 0.1 0.0067 15.8 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3554) TIP120 PF08623.5 ETO02935.1 - 0.0051 16.4 2.4 0.09 12.3 0.9 2.8 1 1 1 2 2 2 1 TATA-binding protein interacting (TIP20) HEAT_PBS PF03130.11 ETO02935.1 - 0.013 15.8 0.0 4 8.1 0.0 2.7 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat HsbA PF12296.3 ETO02935.1 - 0.067 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Hydrophobic surface binding protein A DUF2758 PF10957.3 ETO02935.1 - 0.076 12.8 1.4 7.1 6.5 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2758) DUF148 PF02520.12 ETO02935.1 - 0.081 12.7 1.1 0.26 11.0 0.0 2.3 2 1 1 3 3 3 0 Domain of unknown function DUF148 Syntaphilin PF15290.1 ETO02935.1 - 0.48 9.8 3.7 8.6 5.7 0.0 2.9 3 1 0 3 3 3 0 Golgi-localised syntaxin-1-binding clamp PGG PF13962.1 ETO02937.1 - 0.13 11.8 0.1 0.33 10.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF3993 PF13158.1 ETO02938.1 - 0.076 12.8 0.0 0.2 11.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3993) Peptidase_C47 PF05543.8 ETO02939.1 - 0.048 13.0 0.0 0.095 12.1 0.0 1.4 1 0 0 1 1 1 0 Staphopain peptidase C47 DUF4083 PF13314.1 ETO02940.1 - 0.13 12.0 2.7 0.34 10.7 1.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) ABC2_membrane_2 PF12679.2 ETO02940.1 - 5.2 5.8 6.5 7 5.4 4.5 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein GILT PF03227.11 ETO02941.1 - 0.00018 21.3 1.2 0.00021 21.1 0.1 1.7 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Ank_2 PF12796.2 ETO02942.1 - 5e-09 36.3 0.3 9.3e-09 35.5 0.2 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO02942.1 - 2.8e-08 33.2 0.4 0.00037 20.4 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 ETO02942.1 - 5.5e-07 29.0 0.0 7.5e-06 25.5 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 ETO02942.1 - 1.1e-06 28.9 0.3 1e-05 25.9 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO02942.1 - 2.4e-05 24.4 1.7 6.3e-05 23.0 0.1 2.5 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Saccharop_dh PF03435.13 ETO02942.1 - 0.051 12.5 0.0 0.078 11.9 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase WD40 PF00400.27 ETO02943.1 - 4.2e-23 80.3 1.6 4.7e-12 45.2 0.2 2.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO02943.1 - 0.0027 15.9 0.1 0.34 9.0 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO02943.1 - 0.068 12.9 0.4 3.7 7.3 0.2 2.5 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Glyco_transf_8C PF08437.5 ETO02944.1 - 0.079 12.9 1.1 0.21 11.6 0.8 1.8 1 0 0 1 1 1 0 Glycosyl transferase family 8 C-terminal Fumarate_red_D PF02313.12 ETO02945.1 - 0.024 14.5 0.1 0.029 14.2 0.1 1.1 1 0 0 1 1 1 0 Fumarate reductase subunit D PIG-F PF06699.6 ETO02945.1 - 0.03 14.2 0.0 0.033 14.1 0.0 1.1 1 0 0 1 1 1 0 GPI biosynthesis protein family Pig-F CCDC144C PF14915.1 ETO02947.1 - 0.0018 17.2 1.0 0.0018 17.2 0.7 1.6 2 0 0 2 2 2 1 CCDC144C protein coiled-coil region DUF972 PF06156.8 ETO02947.1 - 0.0098 16.2 0.9 0.0098 16.2 0.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF972) Herpes_BLRF2 PF05812.7 ETO02947.1 - 0.011 15.5 1.0 0.011 15.5 0.7 1.6 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein TSC22 PF01166.13 ETO02947.1 - 0.035 14.0 1.6 0.035 14.0 1.1 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF837 PF05769.6 ETO02947.1 - 0.037 13.5 0.9 0.037 13.5 0.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF837) Atg14 PF10186.4 ETO02947.1 - 0.31 9.9 4.8 0.18 10.6 2.2 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DivIVA PF05103.8 ETO02947.1 - 0.33 11.0 7.3 0.36 10.8 0.5 2.2 2 0 0 2 2 2 0 DivIVA protein DivIC PF04977.10 ETO02947.1 - 0.53 9.8 5.7 0.12 11.9 1.4 1.8 2 0 0 2 2 2 0 Septum formation initiator bZIP_1 PF00170.16 ETO02947.1 - 0.88 9.5 8.2 0.15 12.0 2.2 2.0 2 0 0 2 2 2 0 bZIP transcription factor DUF904 PF06005.7 ETO02947.1 - 1.7 8.9 8.8 0.21 11.9 2.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF4659 PF15558.1 ETO02947.1 - 2.2 6.8 10.3 0.017 13.8 1.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4659) Peptidase_C14 PF00656.17 ETO02948.1 - 2.8e-07 30.4 2.5 3.1e-07 30.3 0.1 2.2 2 0 0 2 2 2 1 Caspase domain RNase_H2_suC PF08615.6 ETO02948.1 - 0.029 14.1 4.7 0.073 12.9 3.3 1.7 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Daxx PF03344.10 ETO02948.1 - 0.037 12.5 15.7 0.046 12.2 10.9 1.2 1 0 0 1 1 1 0 Daxx Family Myc_N PF01056.13 ETO02948.1 - 0.083 12.0 8.1 0.13 11.3 5.6 1.3 1 0 0 1 1 1 0 Myc amino-terminal region His_Phos_1 PF00300.17 ETO02948.1 - 1.2 9.2 0.0 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) alpha-hel2 PF14456.1 ETO02948.1 - 1.4 7.6 11.8 2.4 6.8 8.2 1.3 1 0 0 1 1 1 0 Alpha-helical domain 2 DUF2457 PF10446.4 ETO02948.1 - 4.4 5.9 18.9 7.6 5.1 13.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) UPF0160 PF03690.8 ETO02949.1 - 1.5e-31 110.0 0.0 1.8e-31 109.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Integrin_beta PF00362.13 ETO02950.1 - 0.13 11.1 2.0 0.14 10.9 1.4 1.0 1 0 0 1 1 1 0 Integrin, beta chain Toxin-deaminase PF14424.1 ETO02951.1 - 0.018 14.9 0.7 0.022 14.7 0.5 1.1 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases DUF4402 PF14352.1 ETO02951.1 - 0.042 14.3 0.0 0.075 13.4 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4402) RL11D PF11088.3 ETO02951.1 - 0.2 11.4 2.0 0.75 9.6 0.2 2.1 2 0 0 2 2 2 0 Glycoprotein encoding membrane proteins RL5A and RL6 zf-C3HC4_2 PF13923.1 ETO02952.1 - 0.022 14.7 1.7 0.28 11.2 1.2 2.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO02952.1 - 0.13 12.0 2.6 0.24 11.2 0.5 2.4 2 1 0 2 2 2 0 Ring finger domain HSV_VP16_C PF12149.3 ETO02956.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Herpes simplex virus virion protein 16 C terminal Daxx PF03344.10 ETO02958.1 - 0.49 8.8 21.2 0.61 8.5 14.7 1.2 1 0 0 1 1 1 0 Daxx Family NOA36 PF06524.7 ETO02958.1 - 1.1 8.4 15.9 1.7 7.8 11.0 1.3 1 0 0 1 1 1 0 NOA36 protein GAGA_bind PF06217.7 ETO02958.1 - 1.1 9.1 8.5 1.3 8.9 5.9 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family rve PF00665.21 ETO02959.1 - 2.7e-12 46.8 0.0 3.8e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Tubulin_C PF03953.12 ETO02960.1 - 0.042 13.8 0.1 0.058 13.4 0.1 1.2 1 0 0 1 1 1 0 Tubulin C-terminal domain Kelch_1 PF01344.20 ETO02961.1 - 2.6e-09 36.4 3.8 0.00026 20.4 0.5 3.6 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.1 ETO02961.1 - 3.4e-08 33.1 0.3 0.008 15.9 0.0 3.5 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO02961.1 - 6.2e-06 26.1 1.5 0.099 12.8 0.5 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 ETO02961.1 - 0.00051 19.9 9.7 0.21 11.5 1.4 3.5 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO02961.1 - 0.00071 19.2 2.5 0.036 13.8 0.2 3.4 3 1 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 ETO02961.1 - 0.0013 18.8 0.2 0.7 10.1 0.0 3.5 4 0 0 4 4 4 1 Galactose oxidase, central domain Acetyltransf_CG PF14542.1 ETO02961.1 - 0.067 13.0 0.0 24 4.9 0.0 2.9 3 0 0 3 3 3 0 GCN5-related N-acetyl-transferase DUF1744 PF08490.7 ETO02962.1 - 1.1e-23 83.4 1.9 1.2e-23 83.3 1.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DUF1744 PF08490.7 ETO02963.1 - 4.3e-29 101.3 0.1 4.9e-29 101.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) WD40 PF00400.27 ETO02965.1 - 5.5e-27 92.6 10.3 4e-10 39.1 1.9 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO02965.1 - 8.8e-06 24.1 1.1 0.00041 18.6 0.0 2.8 2 1 1 3 3 3 1 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO02965.1 - 0.021 14.1 0.8 0.037 13.3 0.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4221) Kelch_6 PF13964.1 ETO02965.1 - 0.074 13.2 3.7 4.8 7.5 0.1 3.0 3 0 0 3 3 3 0 Kelch motif YqhG PF11079.3 ETO02968.1 - 0.014 14.1 1.2 0.053 12.3 0.0 2.1 1 1 1 2 2 2 0 Bacterial protein YqhG of unknown function UCH PF00443.24 ETO02969.1 - 9.3e-21 74.1 1.4 1.2e-20 73.7 1.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO02969.1 - 0.014 14.8 0.5 0.014 14.8 0.3 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase PerB PF06590.6 ETO02970.1 - 3 8.1 9.5 14 5.9 0.1 2.9 1 1 2 3 3 3 0 PerB protein RVT_1 PF00078.22 ETO02971.1 - 4.9e-12 45.6 3.0 1e-06 28.2 0.0 2.9 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) SWIRM PF04433.12 ETO02971.1 - 0.089 12.9 2.1 1.1 9.4 0.3 3.1 2 0 0 2 2 2 0 SWIRM domain TPR_11 PF13414.1 ETO02972.1 - 3.3e-12 45.8 2.2 7e-12 44.8 1.6 1.6 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 ETO02972.1 - 3.7e-12 45.2 4.6 6.3e-06 25.5 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO02972.1 - 9.6e-10 38.8 1.1 2.4e-09 37.5 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO02972.1 - 8.1e-08 31.6 8.6 0.00046 19.9 0.4 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO02972.1 - 1.2e-07 31.3 3.4 0.00013 21.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO02972.1 - 2.1e-07 30.9 1.0 0.038 14.6 0.0 3.5 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO02972.1 - 1.1e-06 27.9 5.3 0.0019 17.8 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO02972.1 - 2.4e-06 27.3 0.9 6.2e-06 26.0 0.6 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO02972.1 - 1.4e-05 25.2 0.6 3.6e-05 23.9 0.4 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat KxDL PF10241.4 ETO02972.1 - 0.0016 18.3 0.4 0.004 17.0 0.3 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein TPR_6 PF13174.1 ETO02972.1 - 3.1 8.4 4.7 14 6.3 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat UPF0182 PF03699.8 ETO02974.1 - 0.0077 14.2 7.0 0.0087 14.0 4.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0182) SAGA-Tad1 PF12767.2 ETO02976.1 - 0.7 9.5 11.4 0.1 12.2 5.1 1.5 1 1 1 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF1510 PF07423.6 ETO02976.1 - 7.6 5.8 18.9 0.53 9.6 6.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF1506 PF07405.6 ETO02977.1 - 0.0072 16.3 1.9 0.012 15.6 0.7 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1506) Kelch_2 PF07646.10 ETO02977.1 - 0.073 12.8 3.0 4.8 7.0 0.1 3.9 4 0 0 4 4 4 0 Kelch motif Kelch_1 PF01344.20 ETO02977.1 - 0.12 11.9 1.2 7.9 6.1 0.1 3.1 2 0 0 2 2 2 0 Kelch motif Kelch_6 PF13964.1 ETO02977.1 - 0.18 12.0 3.2 11 6.3 0.1 3.6 3 0 0 3 3 3 0 Kelch motif TFIIF_alpha PF05793.7 ETO02978.1 - 0.13 10.6 2.3 0.17 10.2 1.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Senescence PF06911.7 ETO02979.1 - 1.6e-05 24.7 0.2 2.1e-05 24.3 0.1 1.1 1 0 0 1 1 1 1 Senescence-associated protein zf-CCHC_3 PF13917.1 ETO02985.1 - 0.0005 19.7 0.9 0.0015 18.2 0.6 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 ETO02985.1 - 0.0035 17.1 1.2 0.0056 16.5 0.8 1.3 1 0 0 1 1 1 1 Zinc knuckle Phage_Gp14 PF10666.4 ETO02985.1 - 0.013 15.4 2.4 0.013 15.4 1.6 1.8 2 1 0 2 2 2 0 Phage protein Gp14 PHF5 PF03660.9 ETO02985.1 - 0.023 14.7 0.1 0.042 13.9 0.1 1.4 1 0 0 1 1 1 0 PHF5-like protein Memo PF01875.12 ETO02986.1 - 0.0011 17.9 0.0 0.0016 17.3 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein AAA_32 PF13654.1 ETO02987.1 - 0.031 12.9 0.6 0.037 12.7 0.4 1.1 1 0 0 1 1 1 0 AAA domain EST1_DNA_bind PF10373.4 ETO02988.1 - 0.1 11.8 0.8 0.11 11.7 0.5 1.0 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain TetR_C_8 PF14278.1 ETO02988.1 - 0.31 11.4 2.1 1.4 9.3 0.1 2.2 1 1 1 2 2 2 0 Transcriptional regulator C-terminal region CUE PF02845.11 ETO02989.1 - 0.029 13.8 0.0 0.066 12.7 0.0 1.6 1 0 0 1 1 1 0 CUE domain PUB PF09409.5 ETO02989.1 - 0.043 13.5 2.1 0.18 11.5 0.4 2.6 2 1 0 2 2 2 0 PUB domain PCI PF01399.22 ETO02989.1 - 0.11 12.8 1.1 0.37 11.1 0.2 2.2 1 1 1 2 2 2 0 PCI domain FANCI_S2 PF14676.1 ETO02989.1 - 0.11 12.3 0.8 1 9.2 0.1 2.1 2 0 0 2 2 2 0 FANCI solenoid 2 AgrB PF04647.10 ETO02991.1 - 0.037 13.0 2.4 0.12 11.3 1.7 2.0 1 1 0 1 1 1 0 Accessory gene regulator B Bro-N PF02498.12 ETO02991.1 - 0.054 13.7 0.3 0.084 13.1 0.2 1.3 1 0 0 1 1 1 0 BRO family, N-terminal domain DUF3067 PF11267.3 ETO02991.1 - 0.12 12.4 0.1 0.32 11.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3067) bZIP_1 PF00170.16 ETO02992.1 - 2e-08 34.0 9.7 2e-08 34.0 6.7 2.5 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 ETO02992.1 - 0.0012 18.5 14.5 0.0012 18.5 10.0 2.8 2 1 0 2 2 2 1 Basic region leucine zipper IFT43 PF15305.1 ETO02992.1 - 0.15 12.0 1.8 0.29 11.1 1.3 1.5 1 0 0 1 1 1 0 Intraflagellar transport protein 43 bZIP_Maf PF03131.12 ETO02992.1 - 0.24 11.7 8.6 0.56 10.5 6.0 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor HEAT_2 PF13646.1 ETO02993.1 - 0.07 13.4 0.0 0.081 13.2 0.0 1.2 1 0 0 1 1 1 0 HEAT repeats Kelch_4 PF13418.1 ETO02994.1 - 0.00052 19.7 0.3 0.15 11.8 0.0 2.1 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO02994.1 - 0.0013 18.8 0.4 0.063 13.4 0.0 2.1 1 1 1 2 2 2 1 Kelch motif Kelch_1 PF01344.20 ETO02994.1 - 0.0063 16.0 0.1 0.083 12.4 0.0 2.1 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO02994.1 - 0.0073 16.4 0.0 0.018 15.1 0.0 1.7 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO02994.1 - 0.088 12.7 0.0 3.1 7.8 0.0 2.1 2 0 0 2 2 2 0 Kelch motif Botulinum_HA-17 PF05588.6 ETO02995.1 - 0.094 12.6 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Clostridium botulinum HA-17 protein Phe_hydrox_dim PF07976.7 ETO02996.1 - 0.0069 16.0 0.2 0.29 10.7 0.0 2.0 1 1 1 2 2 2 2 Phenol hydroxylase, C-terminal dimerisation domain DRY_EERY PF09750.4 ETO02996.1 - 0.034 14.2 2.1 0.04 14.0 1.5 1.3 1 0 0 1 1 1 0 Alternative splicing regulator NDK PF00334.14 ETO02996.1 - 0.068 12.9 0.0 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 Nucleoside diphosphate kinase MRP-L46 PF11788.3 ETO02996.1 - 2.8 8.6 7.3 0.51 11.0 1.6 2.0 2 0 0 2 2 2 0 39S mitochondrial ribosomal protein L46 Apolipoprotein PF01442.13 ETO02997.1 - 0.002 17.6 6.9 0.0026 17.2 4.8 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF1664 PF07889.7 ETO02997.1 - 0.0056 16.4 2.7 0.0056 16.4 1.9 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) SIMPL PF04402.9 ETO02997.1 - 0.0057 16.5 1.1 0.0061 16.4 0.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF541) DUF3130 PF11328.3 ETO02997.1 - 0.046 13.7 0.2 0.072 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3130 IncA PF04156.9 ETO02997.1 - 0.058 12.9 18.2 0.017 14.7 10.6 1.5 2 0 0 2 2 2 0 IncA protein Peptidase_C6 PF00851.13 ETO02997.1 - 0.42 9.1 9.6 0.43 9.1 6.6 1.1 1 0 0 1 1 1 0 Helper component proteinase DOG1 PF14144.1 ETO02997.1 - 0.55 10.3 5.5 7.2 6.7 1.0 2.4 1 1 1 2 2 2 0 Seed dormancy control Pox_A_type_inc PF04508.7 ETO02997.1 - 0.62 9.9 3.0 7.6 6.6 0.1 3.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat NPV_P10 PF05531.7 ETO02997.1 - 1.4 9.2 12.8 0.082 13.1 2.9 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2935 PF11155.3 ETO02997.1 - 1.5 8.8 9.4 1.2 9.2 5.4 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) T2SM PF04612.7 ETO02997.1 - 1.7 8.4 6.3 2.2 8.0 4.4 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M DUF4407 PF14362.1 ETO02997.1 - 2.2 7.1 8.2 2.7 6.8 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RNA_pol_Rpb1_2 PF00623.15 ETO02997.1 - 2.3 8.1 7.5 3.4 7.6 5.2 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 2 Cep57_CLD_2 PF14197.1 ETO02997.1 - 4.3 7.3 14.2 3.6 7.6 8.4 2.0 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 PUB PF09409.5 ETO02998.1 - 0.00094 18.8 0.7 0.016 14.9 0.5 2.5 1 1 0 1 1 1 1 PUB domain Sec16 PF12932.2 ETO02998.1 - 0.32 10.9 1.4 1.1 9.2 0.4 2.2 1 1 1 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region EF1G PF00647.14 ETO02998.1 - 0.41 10.3 4.1 0.16 11.6 0.7 2.0 2 1 0 2 2 2 0 Elongation factor 1 gamma, conserved domain CW_binding_1 PF01473.15 ETO02998.1 - 0.44 10.7 4.9 1.1 9.5 3.4 1.7 1 0 0 1 1 1 0 Putative cell wall binding repeat HNH_4 PF13395.1 ETO03000.1 - 0.032 13.8 0.0 0.097 12.3 0.0 1.9 1 0 0 1 1 1 0 HNH endonuclease WD40 PF00400.27 ETO03001.1 - 8.5e-08 31.8 5.9 3.3e-07 29.9 0.3 3.3 3 1 0 3 3 3 1 WD domain, G-beta repeat Glyco_hydro_30 PF02055.11 ETO03001.1 - 0.015 13.5 0.0 0.016 13.4 0.0 1.1 1 0 0 1 1 1 0 O-Glycosyl hydrolase family 30 NACHT PF05729.7 ETO03003.1 - 1.7e-08 34.2 0.0 5.9e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO03003.1 - 0.00052 20.3 0.0 0.00052 20.3 0.0 3.8 4 1 1 5 5 5 1 AAA domain AAA_22 PF13401.1 ETO03003.1 - 0.00096 19.2 0.0 0.0035 17.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO03003.1 - 0.0013 19.5 0.5 0.023 15.4 0.0 3.2 2 1 0 2 2 2 1 AAA domain ATP_bind_2 PF03668.10 ETO03003.1 - 0.0046 16.0 0.1 0.59 9.1 0.0 2.6 2 0 0 2 2 2 2 P-loop ATPase protein family UPF0079 PF02367.12 ETO03003.1 - 0.025 14.1 0.0 0.091 12.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 ETO03003.1 - 0.2 11.6 0.1 0.69 9.8 0.0 1.9 1 1 1 2 2 2 0 AAA ATPase domain PALP PF00291.20 ETO03004.1 - 1.7e-65 221.2 0.0 2e-65 221.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme IPP-2 PF04979.9 ETO03007.1 - 2.1 8.6 8.0 1.1 9.5 3.5 2.0 2 1 0 2 2 2 0 Protein phosphatase inhibitor 2 (IPP-2) WD40 PF00400.27 ETO03009.1 - 1e-30 104.4 3.7 4.9e-10 38.9 0.1 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO03009.1 - 0.0018 16.5 0.2 0.66 8.0 0.0 2.7 1 1 0 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO03009.1 - 0.0075 15.0 7.4 0.13 10.9 1.5 2.6 1 1 1 2 2 2 2 Nup133 N terminal like DUF2963 PF11178.3 ETO03009.1 - 7.8 6.0 9.9 0.55 9.7 0.4 3.1 3 2 0 3 3 3 0 Protein of unknown function (DUF2963) HEAT_EZ PF13513.1 ETO03010.1 - 0.00012 22.4 0.0 0.037 14.5 0.0 2.6 1 1 1 2 2 2 2 HEAT-like repeat HEAT PF02985.17 ETO03010.1 - 0.00014 21.6 0.0 1.3 9.2 0.0 3.7 3 0 0 3 3 3 2 HEAT repeat TIP120 PF08623.5 ETO03010.1 - 0.00017 21.2 0.5 0.0091 15.5 0.0 2.5 1 1 1 2 2 2 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 ETO03010.1 - 0.00019 21.6 0.1 0.00077 19.6 0.1 1.9 1 1 1 2 2 2 1 HEAT repeats DUF3554 PF12074.3 ETO03010.1 - 0.0022 17.5 0.1 0.016 14.6 0.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF3554) XkdW PF09636.5 ETO03010.1 - 0.0086 15.9 0.1 0.19 11.6 0.0 2.4 1 1 1 2 2 2 1 XkdW protein CDC45 PF02724.9 ETO03011.1 - 1.1 7.2 12.9 1.2 7.1 8.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Ndc1_Nup PF09531.5 ETO03011.1 - 5.5 5.2 8.2 6.6 5.0 5.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Lyase_1 PF00206.15 ETO03012.1 - 6.7e-51 173.3 0.2 1e-50 172.7 0.0 1.4 2 0 0 2 2 2 1 Lyase ASL_C2 PF14698.1 ETO03012.1 - 3e-05 24.0 0.1 0.00011 22.2 0.0 2.0 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal Sugar_transport PF06800.7 ETO03013.1 - 0.09 11.8 0.1 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 Sugar transport protein Dynamin_N PF00350.18 ETO03015.1 - 0.16 11.8 0.0 0.16 11.8 0.0 3.8 4 0 0 4 4 4 0 Dynamin family DUF4239 PF14023.1 ETO03015.1 - 7.4 5.8 6.2 3.4 6.9 0.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4239) Kelch_6 PF13964.1 ETO03016.1 - 0.0019 18.2 0.2 0.01 15.9 0.0 1.9 2 0 0 2 2 2 1 Kelch motif UCH PF00443.24 ETO03017.1 - 0.00023 20.3 2.7 0.00023 20.3 1.9 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_M57 PF12388.3 ETO03017.1 - 0.058 12.7 3.3 3.6 6.8 0.1 2.7 2 1 1 3 3 3 0 Dual-action HEIGH metallo-peptidase UPF1_Zn_bind PF09416.5 ETO03018.1 - 0.03 13.9 0.3 0.041 13.4 0.2 1.1 1 0 0 1 1 1 0 RNA helicase (UPF2 interacting domain) ubiquitin PF00240.18 ETO03018.1 - 0.032 13.6 0.1 0.18 11.1 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin family RA PF00788.18 ETO03018.1 - 0.075 13.5 0.0 0.3 11.5 0.0 1.9 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain Chlam_PMP PF02415.12 ETO03020.1 - 0.0011 19.0 30.3 0.32 11.3 0.4 6.1 5 1 0 5 5 5 3 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF4528 PF15031.1 ETO03020.1 - 0.054 13.2 0.2 0.19 11.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4528) Vps52 PF04129.7 ETO03021.1 - 0.0025 16.4 2.8 0.0025 16.4 1.9 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Herpes_teg_N PF04843.7 ETO03021.1 - 0.043 13.2 0.1 0.045 13.1 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region COX5A PF02284.11 ETO03021.1 - 0.073 13.0 0.7 0.25 11.3 0.5 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase subunit Va Sfi1_C PF10638.4 ETO03021.1 - 0.085 13.2 0.8 0.095 13.1 0.6 1.1 1 0 0 1 1 1 0 Spindle body associated protein C-terminus DUF948 PF06103.6 ETO03021.1 - 0.085 12.7 0.4 0.11 12.3 0.3 1.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF1623 PF07785.6 ETO03021.1 - 0.12 12.3 0.6 0.21 11.5 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1623) MRP-S32 PF10210.4 ETO03023.1 - 1.2 9.5 5.3 0.67 10.3 2.5 1.5 1 1 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 DDHD PF02862.12 ETO03025.1 - 0.079 12.7 3.7 0.13 12.0 2.6 1.3 1 0 0 1 1 1 0 DDHD domain ETRAMP PF09716.5 ETO03025.1 - 0.38 10.7 16.1 0.28 11.1 6.3 3.1 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) YqfQ PF14181.1 ETO03025.1 - 6.7 6.7 13.5 12 5.9 9.3 1.3 1 0 0 1 1 1 0 YqfQ-like protein GCD14 PF08704.5 ETO03025.1 - 8 5.8 7.6 12 5.2 5.3 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Imm30 PF15594.1 ETO03026.1 - 0.0024 17.9 1.9 0.0028 17.7 1.3 1.0 1 0 0 1 1 1 1 Immunity protein 30 RE_NgoFVII PF09565.5 ETO03026.1 - 0.018 14.0 3.2 0.02 13.8 2.2 1.1 1 0 0 1 1 1 0 NgoFVII restriction endonuclease Herpes_UL69 PF05459.7 ETO03026.1 - 0.03 13.4 0.1 0.03 13.4 0.1 1.6 2 0 0 2 2 2 0 Herpesvirus transcriptional regulator family HlyD_3 PF13437.1 ETO03026.1 - 0.086 13.1 2.3 0.71 10.2 0.2 2.1 1 1 1 2 2 2 0 HlyD family secretion protein Geminin PF07412.7 ETO03026.1 - 2.1 8.0 13.0 0.075 12.7 3.3 1.9 1 1 1 2 2 2 0 Geminin DUF641 PF04859.7 ETO03026.1 - 4.5 7.0 13.1 0.32 10.7 2.2 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Herpes_UL69 PF05459.7 ETO03027.1 - 0.0067 15.5 0.4 0.0088 15.2 0.2 1.3 1 1 0 1 1 1 1 Herpesvirus transcriptional regulator family HlyD_3 PF13437.1 ETO03027.1 - 0.022 15.0 0.3 0.043 14.1 0.2 1.5 1 1 0 1 1 1 0 HlyD family secretion protein Alpha-amylase_N PF02903.9 ETO03027.1 - 0.044 13.7 3.1 0.062 13.2 2.2 1.4 1 1 0 1 1 1 0 Alpha amylase, N-terminal ig-like domain DUF4163 PF13739.1 ETO03027.1 - 0.17 12.6 5.9 0.22 12.3 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4163) Spore_II_R PF09551.5 ETO03027.1 - 0.32 11.0 4.0 0.36 10.8 2.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) Remorin_C PF03763.8 ETO03027.1 - 5.2 6.6 13.6 6.3 6.3 9.4 1.1 1 0 0 1 1 1 0 Remorin, C-terminal region Phage_GP20 PF06810.6 ETO03027.1 - 6.5 6.1 16.5 7.9 5.9 11.4 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 Geminin PF07412.7 ETO03027.1 - 7.3 6.2 13.3 0.38 10.3 3.9 1.9 1 1 1 2 2 2 0 Geminin Peptidase_M22 PF00814.20 ETO03028.1 - 0.085 12.3 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Glycoprotease family MMS19_N PF14500.1 ETO03029.1 - 0.002 17.4 0.6 0.0031 16.8 0.4 1.3 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT PF02985.17 ETO03029.1 - 0.0089 16.0 0.2 14 6.0 0.0 3.3 3 1 0 3 3 3 2 HEAT repeat MMS19_C PF12460.3 ETO03029.1 - 0.015 14.0 1.5 0.017 13.8 1.0 1.2 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal SusD-like PF12741.2 ETO03029.1 - 0.026 13.1 1.8 0.061 11.9 0.1 1.9 1 1 1 2 2 2 0 Susd and RagB outer membrane lipoprotein DUF2405 PF10293.4 ETO03029.1 - 0.056 13.1 0.1 0.091 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2405) DUF508 PF04370.7 ETO03029.1 - 0.058 13.0 0.3 0.083 12.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) DUF1493 PF07377.7 ETO03030.1 - 0.004 17.2 0.5 0.0063 16.5 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) Herpes_UL1 PF05259.6 ETO03033.1 - 0.33 10.4 1.7 0.37 10.2 0.1 1.8 2 0 0 2 2 2 0 Herpesvirus glycoprotein L DltD_N PF04915.7 ETO03033.1 - 6.5 6.7 15.2 21 5.0 1.4 3.4 1 1 1 2 2 2 0 DltD N-terminal region BRF1 PF07741.8 ETO03034.1 - 0.054 13.7 9.6 0.066 13.4 6.7 1.1 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Topoisom_I_N PF02919.10 ETO03034.1 - 0.22 10.7 8.4 0.23 10.7 5.8 1.0 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment BSMAP PF12280.3 ETO03034.1 - 0.23 11.2 6.6 0.25 11.2 4.6 1.0 1 0 0 1 1 1 0 Brain specific membrane anchored protein FemAB PF02388.11 ETO03034.1 - 0.45 9.1 8.7 0.49 9.0 6.1 1.0 1 0 0 1 1 1 0 FemAB family Eapp_C PF10238.4 ETO03034.1 - 0.5 10.2 6.1 0.61 9.9 4.2 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein LicD PF04991.8 ETO03034.1 - 0.67 10.0 5.3 0.78 9.8 3.7 1.1 1 0 0 1 1 1 0 LicD family Folate_carrier PF01770.13 ETO03034.1 - 0.76 8.2 5.4 0.83 8.0 3.8 1.0 1 0 0 1 1 1 0 Reduced folate carrier DUF1764 PF08576.5 ETO03034.1 - 0.97 10.2 11.0 1.2 9.9 7.6 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) TRAP-gamma PF07074.7 ETO03034.1 - 1.2 8.6 4.3 1.4 8.3 3.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF3807 PF12720.2 ETO03034.1 - 1.4 9.0 12.1 1.7 8.7 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF3886 PF13025.1 ETO03034.1 - 1.4 8.9 21.4 2.1 8.3 14.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) DUF2217 PF10265.4 ETO03034.1 - 2 7.0 7.9 2.3 6.9 5.5 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Peptidase_S49_N PF08496.5 ETO03034.1 - 2.4 7.9 13.1 3.5 7.3 9.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal BRCA-2_helical PF09169.5 ETO03034.1 - 2.8 7.4 7.9 3.6 7.1 5.5 1.1 1 0 0 1 1 1 0 BRCA2, helical DUF4407 PF14362.1 ETO03034.1 - 3.1 6.6 8.1 3.7 6.4 5.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2058 PF09831.4 ETO03034.1 - 3.4 7.5 15.6 4.3 7.1 10.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Band_3_cyto PF07565.8 ETO03034.1 - 3.7 7.0 7.3 4.3 6.7 5.0 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4446 PF14584.1 ETO03034.1 - 3.8 7.3 6.2 4.9 6.9 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) OmpH PF03938.9 ETO03034.1 - 7 6.5 15.9 8.4 6.3 11.0 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4014 PF13198.1 ETO03035.1 - 0.021 15.2 1.9 0.025 14.9 0.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4014) Cut12 PF11500.3 ETO03035.1 - 0.043 13.4 1.7 1.2 8.7 1.2 2.1 1 1 0 1 1 1 0 Spindle pole body formation-associated protein WD40 PF00400.27 ETO03036.1 - 4.7e-12 45.2 2.7 2.5e-10 39.8 0.1 2.8 3 0 0 3 3 3 2 WD domain, G-beta repeat TfoX_N PF04993.8 ETO03037.1 - 0.065 13.0 3.4 0.094 12.5 2.4 1.2 1 0 0 1 1 1 0 TfoX N-terminal domain DUF4407 PF14362.1 ETO03037.1 - 8.6 5.2 8.3 9.5 5.0 5.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hydrolase PF00702.21 ETO03038.1 - 5.9e-05 23.5 0.0 8.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 ETO03038.1 - 0.0094 15.5 0.1 0.018 14.6 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETO03038.1 - 0.042 14.0 0.0 0.069 13.3 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Aminotran_5 PF00266.14 ETO03039.1 - 0.032 12.9 0.1 0.038 12.7 0.1 1.3 1 1 0 1 1 1 0 Aminotransferase class-V NCD1 PF04904.8 ETO03040.1 - 2.7e-06 27.0 0.2 4.7e-06 26.2 0.1 1.4 1 1 0 1 1 1 1 NAB conserved region 1 (NCD1) DUF851 PF05867.6 ETO03040.1 - 0.014 14.6 0.5 0.017 14.3 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF851) SAM_1 PF00536.25 ETO03040.1 - 0.069 13.3 0.1 0.15 12.2 0.0 1.6 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) KSR1-SAM PF13543.1 ETO03040.1 - 0.073 12.8 0.5 0.55 10.0 0.0 1.9 1 1 1 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 YflT PF11181.3 ETO03040.1 - 0.092 12.9 1.2 0.15 12.2 0.8 1.4 1 1 0 1 1 1 0 Heat induced stress protein YflT SAM_2 PF07647.12 ETO03040.1 - 0.098 12.5 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF2935 PF11155.3 ETO03040.1 - 0.28 11.2 2.0 0.44 10.6 1.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) NACHT PF05729.7 ETO03041.1 - 1e-18 67.5 0.0 2.9e-18 66.0 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETO03041.1 - 0.00038 20.4 0.2 0.0027 17.7 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 ETO03041.1 - 0.026 14.2 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain Abdominal-A PF12407.3 ETO03041.1 - 0.037 13.5 0.5 0.037 13.5 0.3 3.2 3 0 0 3 3 3 0 Homeobox protein DUF4014 PF13198.1 ETO03041.1 - 0.052 13.9 0.4 0.14 12.5 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4014) DUF3722 PF12519.3 ETO03041.1 - 0.055 12.6 2.2 0.22 10.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3722) AAA_18 PF13238.1 ETO03041.1 - 0.068 13.4 0.0 0.068 13.4 0.0 3.5 3 1 1 4 4 4 0 AAA domain AAA_22 PF13401.1 ETO03041.1 - 0.086 12.9 1.5 0.26 11.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain SMC_N PF02463.14 ETO03041.1 - 0.098 11.8 0.0 0.098 11.8 0.0 3.0 3 2 1 4 4 4 0 RecF/RecN/SMC N terminal domain Tubulin PF00091.20 ETO03043.1 - 2.4e-63 213.8 0.0 2.9e-63 213.5 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Lipase_3 PF01764.20 ETO03043.1 - 0.0023 17.5 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Misat_Tub_SegII PF10644.4 ETO03043.1 - 0.042 13.8 0.0 0.097 12.7 0.0 1.7 2 0 0 2 2 2 0 Misato Segment II tubulin-like domain Tubulin_2 PF13809.1 ETO03043.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Tubulin_3 PF14881.1 ETO03043.1 - 0.16 11.4 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Tubulin domain Tubulin_C PF03953.12 ETO03044.1 - 1.1e-30 106.2 0.1 1.4e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin C-terminal domain TPR_12 PF13424.1 ETO03045.1 - 6.8e-136 442.4 70.3 3.5e-21 74.9 1.0 9.3 7 2 2 9 9 9 9 Tetratricopeptide repeat TPR_11 PF13414.1 ETO03045.1 - 4.9e-105 343.2 153.6 7.3e-14 51.1 4.5 11.9 4 3 8 13 13 13 13 TPR repeat TPR_1 PF00515.23 ETO03045.1 - 9.6e-101 325.6 126.4 3.3e-08 32.8 1.0 16.3 16 0 0 16 16 16 16 Tetratricopeptide repeat TPR_2 PF07719.12 ETO03045.1 - 1.7e-85 274.2 95.6 7.2e-07 28.6 0.1 16.4 16 0 0 16 16 16 16 Tetratricopeptide repeat TPR_10 PF13374.1 ETO03045.1 - 3e-81 265.3 25.3 2.2e-07 30.5 0.0 16.3 16 0 0 16 16 16 14 Tetratricopeptide repeat TPR_7 PF13176.1 ETO03045.1 - 4e-66 213.6 48.7 0.00031 20.3 0.0 16.8 16 0 0 16 16 16 15 Tetratricopeptide repeat TPR_8 PF13181.1 ETO03045.1 - 1e-65 212.6 122.9 1.3e-05 24.6 0.5 16.8 16 0 0 16 16 16 15 Tetratricopeptide repeat TPR_16 PF13432.1 ETO03045.1 - 2e-46 155.7 12.8 3.5e-05 24.3 0.1 9.7 6 3 2 9 9 9 9 Tetratricopeptide repeat TPR_14 PF13428.1 ETO03045.1 - 6.9e-43 141.2 0.0 0.095 13.3 0.0 15.7 12 4 4 16 16 15 7 Tetratricopeptide repeat TPR_6 PF13174.1 ETO03045.1 - 1.8e-39 131.4 30.2 0.02 15.3 0.1 16.4 16 0 0 16 16 16 9 Tetratricopeptide repeat TPR_17 PF13431.1 ETO03045.1 - 7.2e-28 94.4 70.5 0.0068 16.5 0.3 16.9 16 0 0 16 16 16 10 Tetratricopeptide repeat Apc3 PF12895.2 ETO03045.1 - 3.7e-25 87.8 69.6 1.9e-06 27.8 5.3 8.8 4 3 6 10 10 10 9 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 ETO03045.1 - 2.1e-22 78.0 10.2 0.014 14.5 0.1 11.9 12 0 0 12 12 12 4 SHNi-TPR TPR_19 PF14559.1 ETO03045.1 - 2.5e-19 69.3 21.8 0.00095 19.4 0.0 9.4 6 1 1 9 9 9 5 Tetratricopeptide repeat MIT PF04212.13 ETO03045.1 - 3.2e-14 52.5 72.0 0.029 14.2 0.4 15.7 15 1 1 16 16 16 6 MIT (microtubule interacting and transport) domain TPR_5 PF12688.2 ETO03045.1 - 3.4e-14 52.9 7.0 0.1 12.6 0.0 8.6 4 2 4 8 8 8 5 Tetratrico peptide repeat PPR PF01535.15 ETO03045.1 - 3.7e-08 32.7 23.4 0.17 11.9 0.1 11.6 13 0 0 13 13 13 2 PPR repeat DUF2225 PF09986.4 ETO03045.1 - 5.2e-08 32.6 73.3 0.077 12.4 0.5 10.3 2 1 8 10 10 10 7 Uncharacterized protein conserved in bacteria (DUF2225) RPN7 PF10602.4 ETO03045.1 - 7.2e-08 32.0 60.8 0.0068 15.8 0.2 12.4 7 3 6 13 13 13 5 26S proteasome subunit RPN7 zf-TRAF PF02176.13 ETO03045.1 - 4.7e-05 23.6 1.1 4.7e-05 23.6 0.7 2.2 2 0 0 2 2 2 1 TRAF-type zinc finger TPR_9 PF13371.1 ETO03045.1 - 0.0018 18.1 0.0 13 5.6 0.0 4.9 4 0 0 4 4 3 0 Tetratricopeptide repeat Sel1 PF08238.7 ETO03045.1 - 0.0067 17.0 57.0 1.3 9.7 0.2 13.4 14 0 0 14 14 14 2 Sel1 repeat TPR_3 PF07720.7 ETO03045.1 - 0.029 14.1 0.3 0.029 14.1 0.2 12.2 13 0 0 13 13 12 0 Tetratricopeptide repeat Ovate PF04844.8 ETO03045.1 - 0.045 13.5 0.1 0.2 11.4 0.0 2.2 2 0 0 2 2 1 0 Transcriptional repressor, ovate UVR PF02151.14 ETO03045.1 - 5.7 6.5 12.2 39 3.9 0.1 6.1 5 0 0 5 5 4 0 UvrB/uvrC motif WD40 PF00400.27 ETO03046.1 - 4.2e-34 115.2 5.8 3.8e-11 42.4 0.1 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat eIF2A PF08662.6 ETO03046.1 - 1.1e-07 31.7 0.2 1.6e-07 31.2 0.1 1.3 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO03046.1 - 2.1e-07 29.5 0.7 0.0018 16.4 0.0 2.5 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO03046.1 - 0.0097 14.2 0.1 2 6.6 0.0 1.9 1 1 0 1 1 1 1 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO03046.1 - 0.048 12.7 0.1 0.31 10.1 0.0 2.0 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Resistin PF06954.6 ETO03046.1 - 0.056 13.7 0.0 4.4 7.6 0.0 2.3 1 1 1 2 2 2 0 Resistin PD40 PF07676.7 ETO03046.1 - 0.15 11.7 1.3 3.4 7.4 0.1 2.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO03046.1 - 0.16 10.6 3.3 14 4.2 0.1 3.0 1 1 2 3 3 3 0 Nup133 N terminal like COX6C PF02937.10 ETO03047.1 - 0.024 14.4 0.0 0.081 12.8 0.0 1.8 2 1 0 2 2 2 0 Cytochrome c oxidase subunit VIc WD40 PF00400.27 ETO03048.1 - 2.8e-83 271.0 15.4 1.8e-15 56.1 0.0 6.0 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO03048.1 - 4e-13 49.5 0.0 3.6e-05 23.5 0.0 2.9 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 ETO03048.1 - 8.9e-10 38.4 1.9 4.6e-07 29.5 1.4 3.0 1 1 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO03048.1 - 2.5e-08 32.6 2.0 0.00045 18.6 0.1 3.4 1 1 2 3 3 3 3 Cytochrome D1 heme domain Nup160 PF11715.3 ETO03048.1 - 6.2e-08 31.2 1.9 0.051 11.6 0.0 4.7 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Gmad1 PF10647.4 ETO03048.1 - 1.4e-07 31.1 0.5 0.00022 20.6 0.1 2.9 1 1 1 3 3 3 2 Lipoprotein LpqB beta-propeller domain Proteasome_A_N PF10584.4 ETO03048.1 - 2.5e-06 26.6 5.3 5.2 6.5 0.0 5.9 5 0 0 5 5 5 1 Proteasome subunit A N-terminal signature PD40 PF07676.7 ETO03048.1 - 8.4e-06 25.3 7.6 8.9 6.1 0.0 5.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF1652 PF07865.6 ETO03048.1 - 0.00033 20.1 0.1 12 5.6 0.0 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF1652) DPPIV_N PF00930.16 ETO03048.1 - 0.00056 18.6 0.8 14 4.1 0.0 4.6 1 1 3 5 5 5 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF1258 PF06869.7 ETO03048.1 - 0.0006 18.9 0.0 9.9 5.1 0.0 4.3 1 1 4 5 5 5 0 Protein of unknown function (DUF1258) Nucleoporin_N PF08801.6 ETO03048.1 - 0.00098 17.9 9.5 1.8 7.2 0.0 4.9 1 1 3 4 4 4 2 Nup133 N terminal like DUF3312 PF11768.3 ETO03048.1 - 0.002 16.4 0.0 0.48 8.5 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3312) Reg_prop PF07494.6 ETO03048.1 - 0.005 16.6 1.0 41 4.6 0.0 4.8 5 0 0 5 5 5 0 Two component regulator propeller TolB_N PF04052.8 ETO03048.1 - 0.016 15.2 0.0 86 3.2 0.0 4.7 5 0 0 5 5 5 0 TolB amino-terminal domain TFIIIC_delta PF12657.2 ETO03048.1 - 0.018 14.7 3.2 0.096 12.3 0.3 2.8 2 1 1 3 3 3 0 Transcription factor IIIC subunit delta N-term Me-amine-dh_H PF06433.6 ETO03048.1 - 0.022 13.3 0.0 0.47 9.0 0.0 2.7 1 1 2 3 3 3 0 Methylamine dehydrogenase heavy chain (MADH) NYD-SP28_assoc PF14775.1 ETO03048.1 - 0.059 13.0 1.7 88 2.9 0.0 4.9 6 0 0 6 6 6 0 Sperm tail C-terminal domain Rpn3_C PF08375.6 ETO03048.1 - 0.071 13.5 0.0 12 6.4 0.0 3.2 3 0 0 3 3 3 0 Proteasome regulatory subunit C-terminal ASCH PF04266.9 ETO03048.1 - 0.087 13.2 0.1 16 5.9 0.0 3.6 3 1 0 4 4 4 0 ASCH domain USP7_C2 PF14533.1 ETO03048.1 - 0.088 12.2 0.0 49 3.2 0.0 3.7 5 0 0 5 5 4 0 Ubiquitin-specific protease C-terminal DUF3732 PF12532.3 ETO03048.1 - 0.089 12.3 0.4 18 4.7 0.0 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF3732) Peptidase_S29 PF02907.10 ETO03048.1 - 0.76 9.2 3.7 9.2 5.7 0.0 3.3 1 1 0 2 2 2 0 Hepatitis C virus NS3 protease Cuticle_1 PF08140.6 ETO03048.1 - 8.7 6.2 15.4 39 4.1 0.0 6.6 8 3 0 8 8 6 0 Crustacean cuticle protein repeat Pyrophosphatase PF00719.14 ETO03049.1 - 0.29 10.5 2.6 0.29 10.5 0.7 1.8 2 0 0 2 2 2 0 Inorganic pyrophosphatase Pox_A32 PF04665.7 ETO03050.1 - 7.8e-09 35.1 1.3 1.5e-08 34.2 0.9 1.4 1 0 0 1 1 1 1 Poxvirus A32 protein NACHT PF05729.7 ETO03050.1 - 0.0053 16.4 0.1 0.025 14.2 0.1 2.0 2 0 0 2 2 2 1 NACHT domain G-alpha PF00503.15 ETO03050.1 - 0.016 13.8 0.5 0.19 10.3 0.1 2.0 1 1 1 2 2 2 0 G-protein alpha subunit AAA_22 PF13401.1 ETO03050.1 - 0.017 15.2 0.0 0.13 12.4 0.0 2.3 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 ETO03050.1 - 0.02 14.5 0.1 0.044 13.4 0.1 1.6 1 0 0 1 1 1 0 Archaeal ATPase AAA_10 PF12846.2 ETO03050.1 - 0.021 14.2 0.8 2.5 7.4 0.1 2.2 1 1 0 2 2 2 0 AAA-like domain FtsK_SpoIIIE PF01580.13 ETO03050.1 - 0.065 12.6 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MobB PF03205.9 ETO03050.1 - 0.067 12.9 0.1 0.19 11.4 0.1 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 ETO03050.1 - 0.081 13.0 0.2 0.3 11.2 0.1 2.1 1 1 0 1 1 1 0 RNA helicase Miro PF08477.8 ETO03050.1 - 0.12 12.8 0.0 0.34 11.3 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein AAA_16 PF13191.1 ETO03050.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF3713 PF12506.3 ETO03051.1 - 0.0069 16.4 3.3 0.22 11.6 2.3 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3713) ATG27 PF09451.5 ETO03054.1 - 0.0032 16.7 0.7 0.0041 16.3 0.5 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 Peptidase_M15 PF01427.12 ETO03055.1 - 0.049 13.2 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 D-ala-D-ala dipeptidase RNase_Zc3h12a PF11977.3 ETO03055.1 - 0.12 12.2 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain HEAT_2 PF13646.1 ETO03056.1 - 0.00097 19.3 0.0 0.2 11.9 0.0 2.4 1 1 1 2 2 2 1 HEAT repeats HEAT_EZ PF13513.1 ETO03056.1 - 0.024 15.1 0.0 5 7.7 0.0 3.2 4 1 0 4 4 4 0 HEAT-like repeat TIP120 PF08623.5 ETO03056.1 - 0.043 13.4 1.8 1.1 8.7 0.2 2.3 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) DUF2555 PF10742.4 ETO03056.1 - 0.067 12.8 0.1 3.8 7.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2555) Utp13 PF08625.6 ETO03056.1 - 0.13 11.9 0.8 11 5.6 0.0 2.8 2 1 1 3 3 3 0 Utp13 specific WD40 associated domain Cys_rich_FGFR PF00839.12 ETO03056.1 - 0.52 10.2 0.1 0.52 10.2 0.1 2.9 3 1 1 4 4 4 0 Cysteine rich repeat GILT PF03227.11 ETO03056.1 - 4.6 7.1 7.1 2.4 8.0 0.1 3.3 4 0 0 4 4 4 0 Gamma interferon inducible lysosomal thiol reductase (GILT) Hus1 PF04005.7 ETO03057.1 - 0.71 8.7 4.4 2.2 7.1 0.5 2.0 1 1 1 2 2 2 0 Hus1-like protein Pox_TAA1 PF03295.9 ETO03058.1 - 0.1 12.3 0.9 0.16 11.6 0.1 1.7 2 0 0 2 2 2 0 Poxvirus trans-activator protein A1 C-terminal zf-RING_2 PF13639.1 ETO03059.1 - 1.4 8.8 7.4 0.45 10.3 2.0 2.5 2 0 0 2 2 2 0 Ring finger domain DUF3464 PF11947.3 ETO03059.1 - 8.5 5.8 11.0 2.3 7.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) HlyD_3 PF13437.1 ETO03060.1 - 0.065 13.5 0.0 0.42 10.9 0.0 2.0 1 1 1 2 2 2 0 HlyD family secretion protein DUF2457 PF10446.4 ETO03060.1 - 0.093 11.4 0.2 0.12 11.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF4014 PF13198.1 ETO03064.1 - 0.0095 16.3 0.3 0.024 15.0 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4014) Helicase_C PF00271.26 ETO03065.1 - 9.2e-06 25.4 0.0 2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TFIIB PF00382.14 ETO03065.1 - 0.093 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcription factor TFIIB repeat IL4 PF00727.13 ETO03065.1 - 0.094 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Interleukin 4 Vfa1 PF08432.5 ETO03066.1 - 0.2 11.6 9.2 0.23 11.4 6.3 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CD34_antigen PF06365.7 ETO03066.1 - 0.3 10.6 4.2 0.34 10.5 2.9 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Pneumo_att_G PF05539.6 ETO03066.1 - 0.45 9.8 3.8 0.48 9.7 2.6 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Pox_Ag35 PF03286.9 ETO03066.1 - 0.81 9.1 10.2 0.97 8.9 7.1 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4512 PF14975.1 ETO03066.1 - 0.97 10.2 3.5 1.1 10.0 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Rtf2 PF04641.7 ETO03066.1 - 1.3 8.1 9.0 1.3 8.1 6.2 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Sec62 PF03839.11 ETO03066.1 - 9.8 5.5 7.2 11 5.3 5.0 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 WD40 PF00400.27 ETO03067.1 - 3.4e-19 67.9 2.6 1.9e-09 37.0 0.0 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat WD40 PF00400.27 ETO03068.1 - 4.6e-79 257.7 15.5 7.5e-15 54.1 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO03068.1 - 8.5e-07 27.4 5.1 1.1 7.2 0.0 5.1 2 1 3 6 6 6 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO03068.1 - 0.0008 17.8 0.3 0.42 8.8 0.0 2.5 1 1 2 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO03068.1 - 0.0017 17.1 4.1 0.11 11.2 1.5 3.3 1 1 1 2 2 2 1 Nup133 N terminal like DPPIV_N PF00930.16 ETO03068.1 - 0.0039 15.8 0.1 0.94 7.9 0.0 3.0 3 1 0 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nbas_N PF15492.1 ETO03068.1 - 0.017 14.2 1.3 1.1 8.2 0.0 3.3 1 1 3 4 4 4 0 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 ETO03068.1 - 0.037 13.5 0.1 0.36 10.2 0.1 2.5 1 1 0 1 1 1 0 PQQ-like domain DUF3261 PF11659.3 ETO03068.1 - 0.051 13.1 0.0 0.26 10.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3261) PD40 PF07676.7 ETO03068.1 - 0.087 12.5 2.7 27 4.5 0.0 4.5 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 ETO03069.1 - 4.4e-47 156.3 11.9 2.3e-12 46.3 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO03069.1 - 1e-05 23.9 2.0 0.047 11.8 0.0 3.8 2 1 2 4 4 4 2 Nucleoporin Nup120/160 PD40 PF07676.7 ETO03069.1 - 0.0007 19.2 6.3 4.6 7.0 0.0 5.1 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO03069.1 - 0.014 13.7 1.0 2.1 6.5 0.0 2.5 1 1 1 2 2 2 0 Cytochrome D1 heme domain Arf PF00025.16 ETO03070.1 - 4.8e-75 250.5 0.1 5.7e-75 250.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 ETO03070.1 - 1e-12 47.7 0.0 1.2e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 ETO03070.1 - 1.6e-12 47.0 0.0 2.1e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 ETO03070.1 - 2.5e-10 39.6 1.6 3.4e-08 32.6 0.1 2.4 1 1 2 3 3 3 2 G-protein alpha subunit Gtr1_RagA PF04670.7 ETO03070.1 - 4.9e-09 35.6 0.0 5.7e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 ETO03070.1 - 1.8e-08 34.8 0.0 6.9e-08 33.0 0.0 1.8 1 1 1 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 ETO03070.1 - 1.9e-05 24.5 0.2 3.7e-05 23.6 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 ETO03070.1 - 0.023 13.7 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_33 PF13671.1 ETO03070.1 - 0.023 14.5 0.2 0.065 13.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain DBD_Tnp_Mut PF03108.10 ETO03070.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 MuDR family transposase DUF3958 PF13125.1 ETO03071.1 - 0.032 14.1 0.7 0.032 14.1 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) RhoGAP PF00620.22 ETO03071.1 - 0.19 11.3 4.8 2.8 7.5 0.1 2.4 1 1 1 2 2 2 0 RhoGAP domain DUF1183 PF06682.7 ETO03072.1 - 0.061 12.9 2.4 0.076 12.6 1.5 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) Zip PF02535.17 ETO03072.1 - 0.13 11.2 0.5 0.13 11.2 0.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.9 ETO03072.1 - 1.6 6.6 6.3 1.7 6.5 4.3 1.0 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.27 ETO03073.1 - 2.2e-52 173.1 4.2 4e-08 32.8 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO03073.1 - 1.1e-10 41.5 0.5 0.0004 20.1 0.1 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO03073.1 - 6.6e-05 22.4 12.4 0.062 12.9 0.0 6.2 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.9 ETO03073.1 - 0.00028 19.8 1.5 0.3 9.8 0.0 2.9 1 1 2 3 3 3 3 Coatomer WD associated region DPPIV_N PF00930.16 ETO03073.1 - 0.00089 17.9 0.1 12 4.3 0.0 3.9 2 1 2 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Cytochrom_D1 PF02239.11 ETO03073.1 - 0.01 14.1 0.2 0.72 8.0 0.0 2.8 1 1 2 3 3 3 0 Cytochrome D1 heme domain Nup160 PF11715.3 ETO03073.1 - 0.014 13.5 0.6 0.98 7.4 0.0 2.8 1 1 0 2 2 2 0 Nucleoporin Nup120/160 Proteasome_A_N PF10584.4 ETO03073.1 - 0.02 14.2 2.9 21 4.5 0.0 4.2 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 ETO03074.1 - 1.5e-31 107.0 3.4 7.8e-13 47.7 0.0 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO03074.1 - 3.5e-06 25.5 0.1 0.0016 16.8 0.0 3.1 3 0 0 3 3 3 1 Cytochrome D1 heme domain Kelch_6 PF13964.1 ETO03074.1 - 5.8e-05 23.0 6.1 0.14 12.4 0.1 5.0 4 1 1 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO03074.1 - 0.00012 21.4 1.4 0.3 10.6 0.0 2.9 2 0 0 2 2 2 2 Kelch motif PQQ_2 PF13360.1 ETO03074.1 - 0.0011 18.5 0.0 0.022 14.2 0.0 2.6 3 0 0 3 3 3 1 PQQ-like domain Kelch_3 PF13415.1 ETO03074.1 - 0.0056 16.8 0.3 0.14 12.3 0.0 3.3 4 0 0 4 4 4 1 Galactose oxidase, central domain CENP-K PF11802.3 ETO03074.1 - 0.0097 15.1 0.3 0.17 11.0 0.1 2.1 2 0 0 2 2 2 1 Centromere-associated protein K Nup160 PF11715.3 ETO03074.1 - 0.021 13.0 0.1 0.034 12.2 0.1 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DPPIV_N PF00930.16 ETO03074.1 - 0.021 13.4 0.0 0.53 8.8 0.0 2.2 1 1 1 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF3281 PF11685.3 ETO03074.1 - 0.025 13.7 0.0 0.045 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3281) PQQ PF01011.16 ETO03074.1 - 0.065 12.7 0.0 5.3 6.7 0.0 3.0 3 0 0 3 3 3 0 PQQ enzyme repeat WD40 PF00400.27 ETO03075.1 - 4.7e-26 89.6 8.2 2.8e-11 42.8 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO03075.1 - 1.2e-07 30.3 0.0 0.00028 19.1 0.1 2.0 2 0 0 2 2 2 2 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO03075.1 - 0.015 14.6 1.6 0.029 13.7 0.2 1.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4221) PT PF04886.7 ETO03076.1 - 7.6e-05 21.9 15.7 7.6e-05 21.9 10.9 2.5 2 0 0 2 2 2 2 PT repeat Myosin_head PF00063.16 ETO03077.1 - 2.5e-13 48.9 0.2 2.8e-13 48.8 0.1 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Activator-TraM PF11657.3 ETO03077.1 - 0.038 13.4 0.4 0.053 12.9 0.2 1.2 1 0 0 1 1 1 0 Transcriptional activator TraM Myosin_head PF00063.16 ETO03078.1 - 1.8e-15 56.0 0.6 2.3e-15 55.7 0.4 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) TPR_12 PF13424.1 ETO03080.1 - 1.1e-09 38.1 0.0 1.7e-06 27.8 0.0 1.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO03080.1 - 1.8e-08 33.6 0.3 9.2e-06 25.0 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO03080.1 - 1.6e-06 27.6 0.0 3.1e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 TPR repeat TPR_7 PF13176.1 ETO03080.1 - 1.8e-06 27.3 0.0 0.005 16.5 0.0 2.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO03080.1 - 3.6e-05 23.3 0.1 0.0051 16.6 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO03080.1 - 4.2e-05 23.0 2.9 0.0047 16.5 0.7 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.13 ETO03080.1 - 0.00081 19.2 0.0 0.013 15.3 0.0 2.2 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_17 PF13431.1 ETO03080.1 - 0.086 13.0 0.0 0.47 10.7 0.0 2.3 1 1 0 1 1 1 0 Tetratricopeptide repeat HERV-K_env_2 PF13804.1 ETO03081.1 - 0.032 13.7 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 Retro-transcribing viruses envelope glycoprotein Mem_trans PF03547.13 ETO03081.1 - 3.6 5.7 5.6 0.3 9.3 0.5 1.6 2 0 0 2 2 2 0 Membrane transport protein Herpes_UL4 PF03277.8 ETO03082.1 - 0.073 12.2 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus UL4 family TCP PF03634.8 ETO03082.1 - 6.6 7.1 14.8 6.3 7.1 3.4 2.2 2 0 0 2 2 2 0 TCP family transcription factor DUF948 PF06103.6 ETO03083.1 - 0.0023 17.7 2.6 0.0041 16.9 0.7 2.3 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF948) Snapin_Pallidin PF14712.1 ETO03083.1 - 6.1 7.2 7.4 8.2 6.8 0.0 2.9 3 0 0 3 3 3 0 Snapin/Pallidin DUF4290 PF14123.1 ETO03085.1 - 0.17 11.0 4.0 0.19 10.8 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4290) PaaSYMP PF14738.1 ETO03085.1 - 1.3 8.7 10.1 1.6 8.4 7.0 1.1 1 0 0 1 1 1 0 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 Cullin_binding PF03556.10 ETO03086.1 - 0.0073 16.4 1.9 0.0096 16.0 1.3 1.3 1 0 0 1 1 1 1 Cullin binding Helicase_C PF00271.26 ETO03087.1 - 3.6e-05 23.5 0.0 0.0001 22.0 0.0 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 ETO03087.1 - 0.023 14.6 0.1 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain MannoseP_isomer PF01050.13 ETO03087.1 - 0.094 12.3 0.0 4.9 6.7 0.0 2.2 1 1 0 2 2 2 0 Mannose-6-phosphate isomerase Kelch_1 PF01344.20 ETO03091.1 - 1.3e-08 34.2 3.8 1.9e-05 24.1 0.0 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO03091.1 - 4.6e-08 32.9 2.3 0.00037 20.5 0.1 3.6 3 1 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 ETO03091.1 - 3.5e-06 27.0 0.4 0.00094 19.2 0.0 3.5 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO03091.1 - 7.8e-05 22.3 0.3 0.00064 19.4 0.0 2.7 4 0 0 4 4 4 1 Galactose oxidase, central domain GF_recep_IV PF14843.1 ETO03091.1 - 0.032 13.8 2.4 2.9 7.5 0.2 2.8 2 0 0 2 2 2 0 Growth factor receptor domain IV Noggin PF05806.7 ETO03092.1 - 0.14 11.4 3.5 0.13 11.5 1.0 1.8 1 1 1 2 2 2 0 Noggin SieB PF14163.1 ETO03092.1 - 0.3 10.6 2.2 0.39 10.2 1.2 1.6 1 1 0 1 1 1 0 Superinfection exclusion protein B DUF3474 PF11960.3 ETO03093.1 - 2.2 8.2 5.2 0.55 10.2 1.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) Suf PF05843.9 ETO03093.1 - 4 7.1 9.5 5.1 6.7 6.6 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) AAA_12 PF13087.1 ETO03094.1 - 5.6e-59 198.8 0.0 1.1e-58 197.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 ETO03094.1 - 4.2e-52 177.0 3.0 4.5e-52 176.9 0.3 2.2 3 0 0 3 3 3 1 AAA domain UPF1_Zn_bind PF09416.5 ETO03094.1 - 9.1e-50 168.1 3.4 1.4e-49 167.6 0.9 2.1 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_19 PF13245.1 ETO03094.1 - 2.2e-13 49.7 0.7 5.1e-13 48.5 0.5 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 ETO03094.1 - 4.4e-13 49.2 0.1 1.8e-11 44.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 ETO03094.1 - 7.8e-05 22.3 0.3 0.48 9.8 0.0 3.6 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase Ribosomal_S13_N PF08069.7 ETO03094.1 - 0.0001 22.0 0.1 0.00031 20.5 0.0 1.9 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Helicase_RecD PF05127.9 ETO03094.1 - 0.00029 20.5 0.1 0.0017 18.0 0.1 2.4 2 1 0 2 2 2 1 Helicase DUF2075 PF09848.4 ETO03094.1 - 0.00035 19.6 2.4 0.0023 16.9 0.1 3.1 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 ETO03094.1 - 0.00035 20.4 0.0 0.00072 19.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PIF1 PF05970.9 ETO03094.1 - 0.0007 18.6 0.4 0.72 8.7 0.0 2.6 3 0 0 3 3 3 2 PIF1-like helicase UvrD-helicase PF00580.16 ETO03094.1 - 0.004 16.4 0.9 1.7 7.8 0.0 3.2 2 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain AAA_10 PF12846.2 ETO03094.1 - 0.026 13.9 0.0 0.048 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain KaiC PF06745.8 ETO03094.1 - 0.027 13.5 0.0 0.055 12.5 0.0 1.4 1 0 0 1 1 1 0 KaiC PhoH PF02562.11 ETO03094.1 - 0.042 13.0 0.8 0.1 11.7 0.1 2.0 2 1 0 2 2 1 0 PhoH-like protein AAA_5 PF07728.9 ETO03094.1 - 0.049 13.3 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 ETO03094.1 - 0.056 12.8 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETO03094.1 - 0.1 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 ETO03094.1 - 0.1 12.2 0.8 0.24 11.0 0.0 2.0 2 1 0 2 2 2 0 NACHT domain T2SE PF00437.15 ETO03094.1 - 0.11 11.3 0.0 0.24 10.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.17 ETO03094.1 - 0.14 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RelA_SpoT PF04607.12 ETO03095.1 - 0.0066 16.4 0.4 0.014 15.3 0.1 1.6 2 0 0 2 2 2 1 Region found in RelA / SpoT proteins EpoR_lig-bind PF09067.5 ETO03096.1 - 0.024 14.6 0.7 0.038 13.9 0.5 1.4 1 1 0 1 1 1 0 Erythropoietin receptor, ligand binding Kelch_5 PF13854.1 ETO03096.1 - 0.034 14.1 0.0 2.9 7.9 0.0 2.5 2 0 0 2 2 2 0 Kelch motif GF_recep_IV PF14843.1 ETO03096.1 - 0.077 12.6 0.1 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 Growth factor receptor domain IV DUF2524 PF10732.4 ETO03098.1 - 0.012 15.6 2.6 0.073 13.1 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) DUF2185 PF09951.4 ETO03098.1 - 0.081 12.7 0.2 0.3 10.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2185) UvrD_C PF13361.1 ETO03099.1 - 0.011 15.1 0.6 0.014 14.9 0.4 1.1 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF3829 PF12889.2 ETO03099.1 - 0.055 12.6 0.6 0.065 12.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Pox_polyA_pol_N PF12630.2 ETO03099.1 - 0.15 12.1 1.2 0.16 12.0 0.2 1.6 2 0 0 2 2 2 0 Poxvirus poly(A) polymerase N-terminal domain Seryl_tRNA_N PF02403.17 ETO03099.1 - 0.36 10.8 4.1 1.6 8.7 0.1 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain zf-DNA_Pol PF08996.5 ETO03100.1 - 0.083 12.2 1.4 0.11 11.8 0.8 1.3 1 1 0 1 1 1 0 DNA Polymerase alpha zinc finger ZZ PF00569.12 ETO03101.1 - 0.057 12.9 0.5 0.057 12.9 0.3 2.3 4 0 0 4 4 4 0 Zinc finger, ZZ type zf-C3HC4_2 PF13923.1 ETO03101.1 - 0.43 10.6 3.9 2.6 8.1 1.7 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Peroxin-22 PF12827.2 ETO03103.1 - 0.3 10.7 3.2 0.21 11.3 0.4 2.1 2 1 0 2 2 2 0 Peroxisomal biogenesis protein family PLDc_N PF13396.1 ETO03105.1 - 0.03 13.9 0.1 0.03 13.9 0.1 3.5 3 1 0 3 3 3 0 Phospholipase_D-nuclease N-terminal Claudin_2 PF13903.1 ETO03105.1 - 2.3 7.8 13.2 0.24 11.0 2.9 2.7 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction PsbI PF02532.9 ETO03105.1 - 2.4 7.8 10.1 2.6 7.7 2.0 3.1 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) A_deaminase PF00962.17 ETO03107.1 - 3.9e-07 29.3 0.0 4.3e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase plasmid_Toxin PF12703.2 ETO03108.1 - 0.13 12.0 0.1 0.79 9.5 0.0 2.2 2 1 0 2 2 2 0 Toxin of toxin-antitoxin type 1 system Kinesin PF00225.18 ETO03109.1 - 0.0051 15.5 1.7 0.014 14.1 1.2 1.7 1 0 0 1 1 1 1 Kinesin motor domain Rota_VP2 PF05087.7 ETO03110.1 - 0.34 8.7 7.3 0.39 8.5 5.0 1.0 1 0 0 1 1 1 0 Rotavirus VP2 protein Protocadherin PF08374.6 ETO03110.1 - 0.7 9.4 4.5 0.99 8.9 3.1 1.2 1 0 0 1 1 1 0 Protocadherin DUF218 PF02698.12 ETO03111.1 - 9.7e-19 67.3 0.0 1.4e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain Pep_deformylase PF01327.16 ETO03111.1 - 1.2e-18 66.9 0.0 1.8e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Polypeptide deformylase Rsa3 PF14615.1 ETO03111.1 - 0.11 11.7 0.8 0.24 10.7 0.6 1.5 1 0 0 1 1 1 0 Ribosome-assembly protein 3 2TM PF13239.1 ETO03112.1 - 0.049 13.6 0.3 0.11 12.5 0.2 1.6 1 0 0 1 1 1 0 2TM domain DUF912 PF06024.7 ETO03112.1 - 0.058 13.4 0.2 0.15 12.1 0.0 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3116 PF11313.3 ETO03114.1 - 0.032 13.8 1.2 0.038 13.5 0.3 1.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3116) SMI1_KNR4 PF09346.5 ETO03114.1 - 0.11 12.5 0.1 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) zf-MIZ PF02891.15 ETO03116.1 - 0.0089 15.5 1.1 0.0089 15.5 0.8 2.5 4 0 0 4 4 4 1 MIZ/SP-RING zinc finger zf-C3HC4_2 PF13923.1 ETO03116.1 - 0.018 15.0 2.6 0.12 12.3 0.9 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 ETO03116.1 - 0.79 9.6 4.2 2.6 7.9 1.8 2.6 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.6 ETO03116.1 - 9.9 6.2 8.6 11 6.0 0.9 3.4 2 1 1 3 3 3 0 RING-like domain WD40 PF00400.27 ETO03117.1 - 2.2e-13 49.4 2.9 6.2e-09 35.4 0.8 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO03117.1 - 0.00097 17.3 0.3 0.0016 16.7 0.2 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 TPR_MLP1_2 PF07926.7 ETO03117.1 - 5.8 6.6 27.1 19 5.0 17.5 2.4 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein WD40 PF00400.27 ETO03118.1 - 0.00052 19.7 1.2 0.036 13.9 0.7 2.4 2 1 0 2 2 2 2 WD domain, G-beta repeat DUF2457 PF10446.4 ETO03120.1 - 0.0026 16.5 10.7 0.0037 16.0 7.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) SDA1 PF05285.7 ETO03120.1 - 0.013 14.8 7.5 0.016 14.5 5.2 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 ETO03120.1 - 0.015 13.3 11.2 0.016 13.1 7.8 1.1 1 0 0 1 1 1 0 Nop14-like family Yippee-Mis18 PF03226.9 ETO03120.1 - 0.026 14.5 0.1 0.08 12.9 0.1 1.9 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Daxx PF03344.10 ETO03120.1 - 0.039 12.4 13.7 0.051 12.0 9.5 1.2 1 0 0 1 1 1 0 Daxx Family VAD1-2 PF15310.1 ETO03120.1 - 0.066 12.8 0.6 0.066 12.8 0.4 2.2 2 0 0 2 2 2 0 Vitamin A-deficiency (VAD) rat model signalling Nucleoplasmin PF03066.10 ETO03120.1 - 0.11 12.0 10.2 0.17 11.3 7.1 1.4 1 0 0 1 1 1 0 Nucleoplasmin TRAP_alpha PF03896.11 ETO03120.1 - 0.13 11.2 7.3 0.19 10.6 5.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Spot_14 PF07084.7 ETO03120.1 - 0.14 12.0 2.1 0.13 12.1 0.5 1.7 2 0 0 2 2 2 0 Thyroid hormone-inducible hepatic protein Spot 14 CobT PF06213.7 ETO03120.1 - 0.17 11.0 11.8 0.23 10.5 8.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sigma70_ner PF04546.8 ETO03120.1 - 0.17 11.4 7.2 0.23 11.0 5.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF1510 PF07423.6 ETO03120.1 - 0.59 9.4 10.5 0.93 8.8 7.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2890 PF11081.3 ETO03120.1 - 0.83 9.6 9.6 1.2 9.1 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF4611 PF15387.1 ETO03120.1 - 4.8 7.3 13.4 15 5.8 9.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Bd3614_N PF14442.1 ETO03120.1 - 5.9 6.8 7.6 1.5 8.7 2.8 1.9 2 0 0 2 2 2 0 Bd3614-like deaminase N-terminal Toxin_46 PF15526.1 ETO03121.1 - 0.011 15.9 0.1 0.017 15.2 0.1 1.4 1 0 0 1 1 1 0 Putative toxin 46 Cofilin_ADF PF00241.15 ETO03122.1 - 0.012 15.5 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein YMF19 PF02326.10 ETO03123.1 - 0.21 12.1 7.8 2.9 8.5 1.1 2.5 2 0 0 2 2 2 0 Plant ATP synthase F0 ThuA PF06283.6 ETO03124.1 - 0.072 12.7 1.6 0.087 12.5 0.7 1.4 1 1 0 1 1 1 0 Trehalose utilisation Lipoprotein_10 PF03202.8 ETO03124.1 - 8.9 6.3 7.1 5.3 7.0 3.3 1.7 2 0 0 2 2 2 0 Putative mycoplasma lipoprotein, C-terminal region PPR_1 PF12854.2 ETO03125.1 - 0.035 13.5 2.2 5.5 6.5 0.0 2.6 2 0 0 2 2 2 0 PPR repeat EIF_2_alpha PF07541.7 ETO03125.1 - 0.063 13.0 0.1 0.093 12.4 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit HAND PF09110.6 ETO03126.1 - 1.2 9.5 8.7 6.9 7.1 6.1 2.2 1 1 0 1 1 1 0 HAND DUF3510 PF12022.3 ETO03127.1 - 1.9e-09 37.7 1.9 3.8e-09 36.7 1.3 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3510) AIG1 PF04548.11 ETO03129.1 - 0.044 12.8 0.2 0.044 12.8 0.1 2.0 1 1 1 2 2 2 0 AIG1 family DUF4557 PF15101.1 ETO03129.1 - 0.72 9.6 11.6 0.86 9.4 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF3371 PF11851.3 ETO03129.1 - 4 8.1 16.3 3.1 8.5 6.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3371) SR-25 PF10500.4 ETO03130.1 - 0.0076 15.7 15.2 0.0076 15.7 10.5 3.7 2 2 1 3 3 3 2 Nuclear RNA-splicing-associated protein Foie-gras_1 PF11817.3 ETO03130.1 - 0.34 10.3 3.4 0.16 11.3 0.9 1.6 2 0 0 2 2 2 0 Foie gras liver health family 1 Spore_III_AF PF09581.5 ETO03131.1 - 0.082 12.7 4.8 0.098 12.5 3.3 1.0 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) MIF PF01187.13 ETO03131.1 - 0.11 12.6 0.4 0.13 12.3 0.3 1.3 1 1 0 1 1 1 0 Macrophage migration inhibitory factor (MIF) Peptidase_M18 PF02127.10 ETO03131.1 - 0.23 9.9 2.1 0.24 9.8 1.4 1.0 1 0 0 1 1 1 0 Aminopeptidase I zinc metalloprotease (M18) Kelch_1 PF01344.20 ETO03132.1 - 0.00032 20.1 0.3 2.1 7.9 0.1 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETO03132.1 - 0.013 15.2 0.1 36 4.2 0.0 3.9 4 0 0 4 4 4 0 Galactose oxidase, central domain adh_short_C2 PF13561.1 ETO03133.1 - 1.6e-07 31.3 0.1 1.9e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase YqzE PF14038.1 ETO03133.1 - 0.17 11.6 2.5 0.29 10.8 1.7 1.3 1 0 0 1 1 1 0 YqzE-like protein WD40 PF00400.27 ETO03134.1 - 9.4e-46 152.1 27.4 2.4e-12 46.2 0.0 6.2 6 1 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO03134.1 - 2.1e-10 39.4 5.8 0.018 13.1 0.9 4.8 1 1 3 4 4 4 4 Nucleoporin Nup120/160 V_ATPase_I PF01496.14 ETO03134.1 - 0.095 10.5 16.1 0.17 9.7 11.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Kelch_6 PF13964.1 ETO03134.1 - 3 8.1 12.5 13 6.1 0.3 4.7 4 1 1 5 5 5 0 Kelch motif DUF3464 PF11947.3 ETO03135.1 - 0.0037 16.7 0.3 0.0062 16.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3464) DUF2254 PF10011.4 ETO03135.1 - 0.0069 14.8 1.1 0.009 14.5 0.3 1.5 1 1 0 1 1 1 1 Predicted membrane protein (DUF2254) DUF2069 PF09842.4 ETO03135.1 - 0.025 14.5 1.6 0.025 14.5 1.1 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2069) CDC45 PF02724.9 ETO03135.1 - 0.036 12.1 1.0 0.045 11.7 0.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Pex14_N PF04695.8 ETO03135.1 - 0.042 13.8 1.9 0.08 12.9 1.3 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region 7TM-7TMR_HD PF07698.6 ETO03135.1 - 0.56 9.6 10.1 1.5 8.2 1.0 2.8 2 1 1 3 3 3 0 7TM receptor with intracellular HD hydrolase NRDE-2 PF08424.5 ETO03135.1 - 0.63 8.8 9.7 0.9 8.3 6.7 1.2 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Col_cuticle_N PF01484.12 ETO03135.1 - 0.78 9.4 4.1 33 4.2 0.2 3.4 3 0 0 3 3 3 0 Nematode cuticle collagen N-terminal domain PRP1_N PF06424.7 ETO03135.1 - 1.9 8.8 11.6 2.8 8.2 8.0 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Tox-PLDMTX PF15645.1 ETO03136.1 - 0.0061 16.6 2.0 0.013 15.4 1.4 1.6 1 0 0 1 1 1 1 Dermonecrotoxin of the Papain-like fold Glyco_transf_29 PF00777.13 ETO03138.1 - 0.13 11.4 2.5 0.34 10.0 1.4 1.8 2 0 0 2 2 2 0 Glycosyltransferase family 29 (sialyltransferase) WD40 PF00400.27 ETO03140.1 - 1.3e-14 53.4 7.6 8e-11 41.3 2.3 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO03140.1 - 0.0012 17.1 0.6 0.0021 16.3 0.3 1.5 1 1 0 1 1 1 1 Nucleoporin Nup120/160 DUF3482 PF11981.3 ETO03140.1 - 0.55 9.4 7.6 0.76 8.9 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) MMR_HSR1_C PF08438.5 ETO03140.1 - 0.8 9.9 8.2 1.3 9.2 5.7 1.3 1 0 0 1 1 1 0 GTPase of unknown function C-terminal Spc7 PF08317.6 ETO03140.1 - 0.93 8.0 21.4 1.1 7.8 14.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF641 PF04859.7 ETO03140.1 - 0.94 9.2 15.4 1.3 8.7 4.2 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Bse634I PF07832.6 ETO03140.1 - 1.6 7.8 11.3 1.2 8.2 7.0 1.3 1 1 0 1 1 1 0 Cfr10I/Bse634I restriction endonuclease HSCB_C PF07743.8 ETO03140.1 - 3.6 8.1 14.6 1.1 9.7 0.9 2.3 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain V_ATPase_I PF01496.14 ETO03140.1 - 7.5 4.2 11.7 9.9 3.8 8.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FPL PF09758.4 ETO03141.1 - 0.061 13.0 7.1 0.071 12.8 0.4 2.5 2 1 0 2 2 2 0 Uncharacterised conserved protein Med15_fungi PF05397.7 ETO03143.1 - 0.032 14.1 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 15 UPF0556 PF10572.4 ETO03143.1 - 0.055 12.6 0.0 0.08 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0556 7TMR-DISM_7TM PF07695.6 ETO03144.1 - 0.0054 16.4 0.0 0.0071 16.0 0.0 1.1 1 0 0 1 1 1 1 7TM diverse intracellular signalling DUF2305 PF10230.4 ETO03144.1 - 0.023 14.0 0.2 0.033 13.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF1031 PF06275.6 ETO03144.1 - 0.048 13.6 0.1 0.58 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1031) ACDC PF14733.1 ETO03146.1 - 0.017 15.1 0.6 0.03 14.4 0.4 1.4 1 0 0 1 1 1 0 AP2-coincident C-terminal CTP_transf_3 PF02348.14 ETO03146.1 - 0.065 12.8 0.3 0.07 12.7 0.2 1.0 1 0 0 1 1 1 0 Cytidylyltransferase SpoOE-like PF09388.5 ETO03146.1 - 0.098 12.1 0.1 0.2 11.1 0.1 1.5 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein Tropomyosin_1 PF12718.2 ETO03147.1 - 0.0018 18.1 22.6 0.0018 18.1 15.7 2.1 1 1 1 2 2 2 1 Tropomyosin like ATG16 PF08614.6 ETO03147.1 - 0.025 14.4 25.1 0.095 12.5 9.1 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.7 ETO03147.1 - 0.031 14.0 28.8 0.23 11.2 10.4 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2779 PF11074.3 ETO03147.1 - 0.056 13.4 8.6 0.19 11.7 6.0 1.7 1 1 0 1 1 1 0 Domain of unknown function(DUF2779) HrpB7 PF09486.5 ETO03147.1 - 0.1 12.5 9.4 1.2 9.0 1.5 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) TMF_DNA_bd PF12329.3 ETO03147.1 - 0.11 12.2 32.4 0.82 9.5 2.9 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Filament PF00038.16 ETO03147.1 - 0.11 11.8 24.4 0.049 13.0 9.9 2.0 1 1 1 2 2 2 0 Intermediate filament protein NBP1 PF08537.5 ETO03147.1 - 0.13 11.4 17.6 0.14 11.3 12.2 1.0 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 GAS PF13851.1 ETO03147.1 - 0.17 11.0 27.1 1.1 8.4 18.8 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding YscO PF07321.7 ETO03147.1 - 0.24 11.2 24.4 0.16 11.7 9.0 2.2 1 1 1 2 2 2 0 Type III secretion protein YscO AAA_13 PF13166.1 ETO03147.1 - 0.25 9.7 21.7 0.34 9.3 15.1 1.1 1 0 0 1 1 1 0 AAA domain HALZ PF02183.13 ETO03147.1 - 0.26 11.0 12.4 0.57 9.9 0.9 3.6 2 1 1 3 3 3 0 Homeobox associated leucine zipper bZIP_2 PF07716.10 ETO03147.1 - 0.29 10.9 23.0 0.11 12.2 2.7 3.5 2 1 1 3 3 3 0 Basic region leucine zipper Rootletin PF15035.1 ETO03147.1 - 0.33 10.9 24.9 2.2 8.2 17.2 1.9 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Mnd1 PF03962.10 ETO03147.1 - 0.44 10.1 23.9 1.6 8.3 8.7 2.1 1 1 1 2 2 2 0 Mnd1 family Reo_sigmaC PF04582.7 ETO03147.1 - 0.48 9.5 3.2 2.2 7.4 2.4 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF4618 PF15397.1 ETO03147.1 - 0.55 9.5 24.1 0.22 10.8 9.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) DUF4633 PF15464.1 ETO03147.1 - 0.72 9.7 4.3 1 9.1 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) UPF0242 PF06785.6 ETO03147.1 - 0.77 8.3 22.0 1.6 7.3 15.2 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) DUF3584 PF12128.3 ETO03147.1 - 1 6.6 26.4 1.3 6.2 18.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) IncA PF04156.9 ETO03147.1 - 1.4 8.5 27.1 13 5.2 18.8 2.2 1 1 0 1 1 1 0 IncA protein ADIP PF11559.3 ETO03147.1 - 1.4 8.7 29.0 1 9.2 10.9 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 ETO03147.1 - 1.5 9.1 23.0 2.8 8.3 3.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF4144 PF13642.1 ETO03147.1 - 1.9 8.8 10.4 9.6 6.6 6.0 2.1 1 1 1 2 2 2 0 protein structure with unknown function Mod_r PF07200.8 ETO03147.1 - 1.9 8.4 23.2 3.2 7.6 8.8 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Ax_dynein_light PF10211.4 ETO03147.1 - 2 8.1 28.7 2.8 7.7 8.5 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain Spc7 PF08317.6 ETO03147.1 - 2.3 6.8 24.7 6.7 5.2 17.1 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein Pox_A_type_inc PF04508.7 ETO03147.1 - 2.5 8.1 0.0 2.5 8.1 0.0 3.1 4 0 0 4 4 2 0 Viral A-type inclusion protein repeat Phage_GP20 PF06810.6 ETO03147.1 - 2.5 7.5 28.5 2.1 7.7 4.7 2.5 1 1 1 2 2 2 0 Phage minor structural protein GP20 MbeB_N PF04837.7 ETO03147.1 - 2.9 8.0 11.0 0.076 13.1 1.7 2.7 2 1 1 3 3 3 0 MbeB-like, N-term conserved region NPV_P10 PF05531.7 ETO03147.1 - 3.6 7.9 17.0 12 6.2 1.7 3.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein AcylCoA_dehyd_C PF12186.3 ETO03147.1 - 3.6 7.4 10.3 7.8 6.3 0.5 2.8 2 1 1 3 3 3 0 Acyl-CoA dehydrogenase C terminal Baculo_PEP_C PF04513.7 ETO03147.1 - 3.7 7.3 11.2 28 4.5 7.8 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4168 PF13767.1 ETO03147.1 - 3.9 8.1 18.0 4.7 7.9 7.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4168) DUF4200 PF13863.1 ETO03147.1 - 3.9 7.4 29.4 4.9 7.1 11.5 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) YlqD PF11068.3 ETO03147.1 - 4.4 7.3 30.1 5.4 7.0 10.8 2.2 1 1 1 2 2 2 0 YlqD protein DUF904 PF06005.7 ETO03147.1 - 5 7.4 28.0 3.7e+03 -1.8 19.4 3.1 1 1 0 1 1 0 0 Protein of unknown function (DUF904) DUF848 PF05852.6 ETO03147.1 - 5.1 6.9 18.4 3.8 7.3 7.7 2.4 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) PspB PF06667.7 ETO03147.1 - 5.1 7.0 11.6 7.9 6.4 0.9 3.3 1 1 2 3 3 3 0 Phage shock protein B Mito_fiss_reg PF05308.6 ETO03147.1 - 5.3 6.3 9.2 8 5.7 6.4 1.4 1 1 0 1 1 1 0 Mitochondrial fission regulator APG6 PF04111.7 ETO03147.1 - 5.8 5.8 26.8 11 4.9 18.6 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 XFP_C PF09363.5 ETO03147.1 - 6.2 6.1 9.1 1.1 8.6 1.0 2.1 1 1 1 2 2 2 0 XFP C-terminal domain DUF3450 PF11932.3 ETO03147.1 - 6.4 5.9 25.6 0.14 11.4 10.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) V_ATPase_I PF01496.14 ETO03147.1 - 8.1 4.1 16.2 10 3.7 11.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spectrin PF00435.16 ETO03147.1 - 9.4 6.5 24.5 8.4 6.7 3.6 2.9 1 1 2 3 3 3 0 Spectrin repeat Raftlin PF15250.1 ETO03148.1 - 0.03 12.8 11.9 0.038 12.5 8.2 1.1 1 0 0 1 1 1 0 Raftlin PAT1 PF09770.4 ETO03148.1 - 1.7 6.7 30.0 2 6.5 20.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GAGA_bind PF06217.7 ETO03148.1 - 3.8 7.3 18.8 5.2 6.9 13.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Pneumo_att_G PF05539.6 ETO03148.1 - 6.7 5.9 10.3 8.1 5.7 7.1 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G YajC PF02699.10 ETO03150.1 - 0.075 12.7 0.1 0.31 10.7 0.1 2.0 1 0 0 1 1 1 0 Preprotein translocase subunit DUF912 PF06024.7 ETO03150.1 - 1.4 9.0 10.8 1.2 9.1 5.1 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) zf-CCHC_4 PF14392.1 ETO03151.1 - 0.057 13.1 1.3 0.057 13.1 0.9 2.4 3 1 0 3 3 3 0 Zinc knuckle zinc_ribbon_2 PF13240.1 ETO03151.1 - 0.24 10.9 3.9 6.4 6.4 1.1 2.8 2 0 0 2 2 2 0 zinc-ribbon domain DUF2296 PF10058.4 ETO03151.1 - 1.4 8.7 5.3 0.83 9.4 2.1 1.8 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Med2 PF11214.3 ETO03152.1 - 0.042 13.8 4.6 0.048 13.6 3.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 2 Noelin-1 PF12308.3 ETO03152.1 - 0.23 11.2 1.4 0.26 11.0 1.0 1.3 1 0 0 1 1 1 0 Neurogenesis glycoprotein DUF4175 PF13779.1 ETO03152.1 - 0.25 9.0 4.9 0.27 8.8 3.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CAAD PF14159.1 ETO03153.1 - 0.17 11.5 1.3 0.62 9.7 0.4 2.2 1 1 1 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Picorna_P3A PF06363.6 ETO03154.1 - 0.039 13.9 0.2 0.049 13.6 0.2 1.2 1 0 0 1 1 1 0 Picornaviridae P3A protein Baculo_PEP_C PF04513.7 ETO03156.1 - 0.0085 15.9 0.1 0.01 15.6 0.1 1.0 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF45 PF01863.12 ETO03156.1 - 0.013 15.3 0.9 0.013 15.2 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF45 Brix PF04427.13 ETO03156.1 - 0.04 13.5 0.1 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Brix domain Phospholip_B PF04916.8 ETO03156.1 - 0.045 11.8 0.9 0.049 11.7 0.6 1.0 1 0 0 1 1 1 0 Phospholipase B DUF1772 PF08592.6 ETO03156.1 - 1.8 8.2 5.0 2.6 7.7 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) DUF4014 PF13198.1 ETO03156.1 - 2.6 8.5 4.3 8.5 6.8 2.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4014) U-box PF04564.10 ETO03157.1 - 2.2e-10 40.3 0.1 7.5e-10 38.6 0.1 1.8 1 1 0 1 1 1 1 U-box domain CPSase_L_D3 PF02787.14 ETO03158.1 - 0.054 13.2 1.2 0.092 12.5 0.1 1.8 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Noelin-1 PF12308.3 ETO03158.1 - 0.32 10.8 2.3 0.21 11.3 0.2 1.7 2 0 0 2 2 2 0 Neurogenesis glycoprotein Sigma_reg_C PF13791.1 ETO03158.1 - 0.93 9.5 10.0 0.68 9.9 0.6 2.2 2 0 0 2 2 2 0 Sigma factor regulator C-terminal DUF2057 PF09829.4 ETO03161.1 - 0.021 14.5 1.2 0.03 13.9 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) WBS28 PF15164.1 ETO03161.1 - 0.1 11.6 0.1 6.2 5.8 0.0 2.1 2 0 0 2 2 2 0 Williams-Beuren syndrome chromosomal region 28 protein homologue Cas_Csm6 PF09659.5 ETO03161.1 - 0.27 9.7 2.1 0.16 10.5 0.4 1.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csm6) Kelch_2 PF07646.10 ETO03162.1 - 0.0001 21.8 0.3 0.39 10.5 0.0 2.9 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.1 ETO03162.1 - 0.00098 19.0 0.3 0.14 12.1 0.1 3.0 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETO03162.1 - 0.002 17.8 0.1 0.027 14.2 0.0 2.9 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO03162.1 - 0.017 15.2 1.0 2.7 8.3 0.0 3.5 3 1 0 3 3 3 0 Kelch motif Kelch_1 PF01344.20 ETO03162.1 - 1.1 8.8 5.5 18 4.9 0.0 3.2 3 1 0 3 3 3 0 Kelch motif TPR_12 PF13424.1 ETO03163.1 - 1.6e-130 425.3 22.5 1.2e-25 89.1 0.5 4.4 1 1 6 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.1 ETO03163.1 - 2.1e-53 176.8 0.0 3.6e-09 36.2 0.0 6.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.23 ETO03163.1 - 3e-44 146.8 41.6 2.2e-09 36.5 1.6 7.2 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.1 ETO03163.1 - 1.3e-43 143.3 2.7 3.5e-08 32.6 0.0 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETO03163.1 - 5.6e-42 141.2 18.4 9.5e-14 50.7 0.2 4.5 3 2 1 4 4 4 4 TPR repeat TPR_2 PF07719.12 ETO03163.1 - 2.7e-36 120.5 23.7 6.5e-08 31.9 0.2 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 ETO03163.1 - 3.7e-31 104.5 51.8 4.7e-08 32.2 0.5 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.1 ETO03163.1 - 8e-23 78.6 11.6 0.0025 17.8 0.1 7.2 7 0 0 7 7 6 6 Tetratricopeptide repeat Apc3 PF12895.2 ETO03163.1 - 5.4e-12 45.6 16.4 0.00035 20.6 1.4 4.5 1 1 3 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 ETO03163.1 - 7.9e-12 45.5 0.0 0.0033 18.0 0.0 4.3 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO03163.1 - 1.8e-11 43.5 0.0 0.31 11.7 0.0 5.3 4 1 2 6 6 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO03163.1 - 2.3e-11 43.3 2.6 0.36 11.4 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_3 PF07720.7 ETO03163.1 - 6.1e-10 38.6 22.9 0.0022 17.7 0.3 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat SNAP PF14938.1 ETO03163.1 - 8.9e-10 38.1 10.4 0.00024 20.3 0.3 4.0 1 1 2 4 4 4 3 Soluble NSF attachment protein, SNAP MIT PF04212.13 ETO03163.1 - 1.7e-09 37.4 26.2 0.035 13.9 0.1 6.5 7 0 0 7 7 6 4 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.4 ETO03163.1 - 5.3e-09 35.1 0.3 0.69 9.2 0.0 6.2 7 0 0 7 7 6 2 SHNi-TPR TPR_19 PF14559.1 ETO03163.1 - 5.4e-09 36.2 0.4 0.03 14.6 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat Sel1 PF08238.7 ETO03163.1 - 6e-08 33.0 14.3 0.23 12.1 0.1 6.1 7 0 0 7 7 6 3 Sel1 repeat PPR PF01535.15 ETO03163.1 - 7.8e-07 28.6 17.6 1.6 8.8 0.1 6.3 6 0 0 6 6 6 1 PPR repeat Ten1_2 PF15490.1 ETO03163.1 - 0.00033 20.2 0.0 14 5.3 0.0 4.7 1 1 5 6 6 6 0 Telomere-capping, CST complex subunit DUF3568 PF12092.3 ETO03163.1 - 0.00045 19.9 7.5 0.18 11.4 0.3 3.8 1 1 2 3 3 3 2 Protein of unknown function (DUF3568) Musclin PF11037.3 ETO03163.1 - 0.0012 18.4 0.0 32 4.1 0.0 4.6 5 0 0 5 5 5 0 Insulin-resistance promoting peptide in skeletal muscle RPN7 PF10602.4 ETO03163.1 - 0.0013 18.1 13.6 1.5 8.1 0.3 4.8 2 2 2 5 5 5 1 26S proteasome subunit RPN7 Mob_Pre PF01076.14 ETO03163.1 - 0.0013 18.3 5.2 0.79 9.3 0.0 3.9 1 1 4 5 5 5 2 Plasmid recombination enzyme ATP-synt_E_2 PF08112.6 ETO03163.1 - 0.0015 18.5 14.7 2.9 8.0 0.0 6.2 6 0 0 6 6 6 1 ATP synthase epsilon subunit DUF2225 PF09986.4 ETO03163.1 - 0.0019 17.6 9.8 0.052 12.9 0.1 3.4 1 1 3 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_5 PF12688.2 ETO03163.1 - 0.0032 17.4 0.0 2.6 8.1 0.0 3.9 3 1 1 4 4 4 1 Tetratrico peptide repeat TPR_21 PF09976.4 ETO03163.1 - 0.0047 16.8 0.8 0.35 10.8 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat FATC PF02260.15 ETO03163.1 - 0.024 14.0 3.2 43 3.6 0.3 4.1 4 0 0 4 4 4 0 FATC domain mRNA_cap_C PF03919.10 ETO03163.1 - 0.031 14.5 0.0 83 3.5 0.0 4.2 3 1 1 4 4 4 0 mRNA capping enzyme, C-terminal domain TCTP PF00838.12 ETO03163.1 - 0.61 10.0 4.0 27 4.6 0.0 3.6 1 1 3 4 4 4 0 Translationally controlled tumour protein DUF627 PF04781.7 ETO03163.1 - 1.7 8.2 18.8 10 5.7 2.0 5.8 4 2 1 5 5 5 0 Protein of unknown function (DUF627) Fis1_TPR_C PF14853.1 ETO03163.1 - 6.3 6.7 19.2 5 7.0 0.2 5.0 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat PPR_2 PF13041.1 ETO03163.1 - 7.4 6.6 17.2 36 4.4 0.2 5.6 5 1 1 6 6 6 0 PPR repeat family Pox_A32 PF04665.7 ETO03166.1 - 0.00097 18.4 0.3 0.0029 16.9 0.2 1.8 1 0 0 1 1 1 1 Poxvirus A32 protein Lipoprotein_20 PF13942.1 ETO03167.1 - 0.11 12.0 0.2 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 YfhG lipoprotein HEAT PF02985.17 ETO03168.1 - 2.5e-08 33.3 0.0 0.0099 15.8 0.0 2.8 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.1 ETO03168.1 - 7.2e-07 29.3 0.0 1.8e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 HEAT repeats Vac14_Fab1_bd PF12755.2 ETO03168.1 - 0.00072 19.8 0.1 0.076 13.4 0.0 2.7 1 1 1 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 ETO03168.1 - 0.0019 18.6 0.0 0.0036 17.7 0.0 1.5 1 0 0 1 1 1 1 HEAT-like repeat Activator-TraM PF11657.3 ETO03168.1 - 0.0068 15.8 0.1 0.018 14.5 0.1 1.6 1 1 0 1 1 1 1 Transcriptional activator TraM HEAT_PBS PF03130.11 ETO03168.1 - 0.11 12.9 0.0 7.2 7.3 0.0 2.8 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat XkdW PF09636.5 ETO03168.1 - 0.37 10.6 1.7 22 4.9 0.1 2.7 1 1 2 3 3 3 0 XkdW protein MIP-T3 PF10243.4 ETO03169.1 - 0.053 11.9 43.2 0.062 11.7 29.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1777 PF08648.7 ETO03169.1 - 3.7 7.2 105.0 1.5e+04 -10.0 72.7 3.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) PRP38_assoc PF12871.2 ETO03169.1 - 9 6.9 120.9 8.9e+02 0.5 33.4 3.3 1 1 1 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DASH_Spc34 PF08657.5 ETO03171.1 - 0.047 13.3 4.2 0.056 13.0 2.9 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 CMV_US PF08001.6 ETO03172.1 - 0.24 10.4 2.1 9.4 5.2 0.4 2.4 2 0 0 2 2 2 0 CMV US Gly_radical PF01228.16 ETO03173.1 - 0.048 14.0 0.0 0.055 13.8 0.0 1.2 1 0 0 1 1 1 0 Glycine radical PPR PF01535.15 ETO03174.1 - 9.4e-07 28.4 0.9 0.011 15.6 0.0 3.1 3 0 0 3 3 3 2 PPR repeat PPR_2 PF13041.1 ETO03174.1 - 0.00029 20.7 2.6 0.0023 17.8 0.1 2.8 2 1 1 3 3 3 1 PPR repeat family DUF1900 PF08954.6 ETO03174.1 - 0.0013 18.3 1.0 0.0097 15.4 0.3 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF1900) PPR_1 PF12854.2 ETO03174.1 - 0.043 13.3 0.1 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 PPR repeat PPR_3 PF13812.1 ETO03174.1 - 0.047 13.9 0.0 20 5.8 0.0 2.7 3 0 0 3 3 3 0 Pentatricopeptide repeat domain Nitrate_red_gam PF02665.9 ETO03175.1 - 0.19 11.0 0.5 0.76 9.0 0.0 1.8 2 0 0 2 2 2 0 Nitrate reductase gamma subunit WD40 PF00400.27 ETO03176.1 - 3.1e-33 112.4 0.6 7.6e-07 28.7 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO03176.1 - 1.6e-10 41.0 0.8 0.00022 20.9 0.2 3.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO03176.1 - 4e-05 21.9 0.1 0.064 11.3 0.0 3.4 2 1 0 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO03176.1 - 7e-05 21.7 0.3 1.2 7.8 0.0 3.2 1 1 2 3 3 3 2 Nup133 N terminal like Nbas_N PF15492.1 ETO03176.1 - 0.00011 21.4 0.5 1.6 7.7 0.0 3.8 2 1 3 5 5 5 2 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 ETO03176.1 - 0.0021 16.3 0.0 0.0074 14.6 0.0 1.8 2 0 0 2 2 2 1 Cytochrome D1 heme domain Mid2 PF04478.7 ETO03176.1 - 0.003 16.9 0.2 0.054 12.8 0.0 2.3 1 1 0 2 2 2 1 Mid2 like cell wall stress sensor Hira PF07569.6 ETO03176.1 - 0.0087 15.2 1.4 4.6 6.3 0.1 3.7 1 1 2 3 3 3 1 TUP1-like enhancer of split DUF2684 PF10885.3 ETO03176.1 - 0.056 13.3 0.0 0.37 10.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2684) PD40 PF07676.7 ETO03176.1 - 0.21 11.2 1.4 22 4.8 0.0 4.0 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat TLD PF07534.11 ETO03178.1 - 0.002 18.1 1.0 0.0039 17.1 0.3 1.8 1 1 0 1 1 1 1 TLD MNSV_P7B PF06692.6 ETO03178.1 - 0.28 10.9 3.2 0.37 10.5 0.5 2.6 2 1 0 2 2 2 0 Melon necrotic spot virus P7B protein Mlp PF03304.8 ETO03178.1 - 1.3 8.9 5.3 0.56 10.2 1.4 1.8 2 0 0 2 2 2 0 Mlp lipoprotein family Helicase_C PF00271.26 ETO03179.1 - 0.017 14.9 0.0 0.059 13.2 0.0 1.9 2 0 0 2 2 2 0 Helicase conserved C-terminal domain VWA_2 PF13519.1 ETO03180.1 - 0.0018 18.3 0.0 0.7 9.9 0.0 2.2 1 1 1 2 2 2 2 von Willebrand factor type A domain DUF1722 PF08349.6 ETO03180.1 - 0.09 12.6 0.2 0.41 10.5 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1722) VWA_3 PF13768.1 ETO03180.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain Kelch_6 PF13964.1 ETO03181.1 - 4.4e-06 26.6 0.1 0.003 17.6 0.0 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 ETO03181.1 - 1.5e-05 24.6 0.3 0.0075 16.0 0.0 2.3 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO03181.1 - 0.0072 15.8 0.3 0.0072 15.8 0.2 1.8 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO03181.1 - 0.02 15.0 0.0 0.069 13.3 0.0 1.9 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO03181.1 - 0.051 13.5 0.2 0.33 10.9 0.2 2.0 2 0 0 2 2 2 0 Kelch motif HEAT PF02985.17 ETO03182.1 - 2.9e-07 29.9 0.0 0.86 9.8 0.0 4.7 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 ETO03182.1 - 4.9e-06 26.7 0.0 0.051 13.8 0.0 2.8 1 1 3 4 4 4 3 HEAT repeats CLASP_N PF12348.3 ETO03182.1 - 3.1e-05 23.4 5.9 0.0012 18.2 0.7 2.4 2 1 0 2 2 2 2 CLASP N terminal FANCI_S1 PF14675.1 ETO03182.1 - 8.9e-05 21.9 3.7 0.00035 20.0 0.5 2.5 1 1 0 2 2 2 1 FANCI solenoid 1 Cnd1 PF12717.2 ETO03182.1 - 0.0015 18.4 16.8 0.0016 18.3 3.1 3.1 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 N_Asn_amidohyd PF14736.1 ETO03182.1 - 0.0074 15.1 0.4 0.046 12.5 0.1 2.1 1 1 0 2 2 2 1 Protein N-terminal asparagine amidohydrolase SRA1 PF07304.6 ETO03182.1 - 0.014 15.1 0.7 0.059 13.1 0.5 2.1 1 1 1 2 2 2 0 Steroid receptor RNA activator (SRA1) Lig_chan-Glu_bd PF10613.4 ETO03182.1 - 0.028 14.3 0.1 3.2 7.8 0.0 2.8 2 0 0 2 2 2 0 Ligated ion channel L-glutamate- and glycine-binding site DNA_alkylation PF08713.6 ETO03182.1 - 0.03 13.8 2.9 0.13 11.7 0.9 2.3 1 1 1 2 2 2 0 DNA alkylation repair enzyme HEAT_EZ PF13513.1 ETO03182.1 - 0.035 14.6 0.0 7.7 7.1 0.0 3.2 3 0 0 3 3 2 0 HEAT-like repeat MOR2-PAG1_C PF14225.1 ETO03182.1 - 0.036 13.8 8.0 0.053 13.2 1.3 2.8 1 1 1 3 3 3 0 Cell morphogenesis C-terminal P16-Arc PF04699.9 ETO03182.1 - 0.13 12.2 0.2 0.13 12.2 0.1 3.1 2 2 1 4 4 4 0 ARP2/3 complex 16 kDa subunit (p16-Arc) DNA_ligase_A_N PF04675.9 ETO03182.1 - 0.19 11.5 4.6 1.6 8.4 0.1 3.3 1 1 2 3 3 3 0 DNA ligase N terminus UME PF08064.8 ETO03182.1 - 0.25 11.3 6.5 6.2 6.8 0.0 4.4 3 2 1 4 4 4 0 UME (NUC010) domain AAA PF00004.24 ETO03185.1 - 3.8e-11 43.2 0.0 0.00016 21.9 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETO03185.1 - 4.5e-10 39.3 0.1 4.4e-06 26.4 0.0 3.6 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETO03185.1 - 6.4e-07 29.5 0.0 0.063 13.4 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 ETO03185.1 - 4.9e-05 23.2 0.1 0.0078 16.1 0.0 3.2 3 0 0 3 3 2 1 AAA domain ABC_tran PF00005.22 ETO03185.1 - 5.1e-05 23.6 0.0 0.0015 18.8 0.0 2.7 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.1 ETO03185.1 - 0.00028 20.9 0.2 0.029 14.3 0.0 3.5 3 1 1 4 4 4 1 AAA ATPase domain Arch_ATPase PF01637.13 ETO03185.1 - 0.00053 19.7 0.8 0.055 13.1 0.0 3.7 3 1 0 3 3 2 1 Archaeal ATPase Viral_helicase1 PF01443.13 ETO03185.1 - 0.00069 19.2 0.0 0.013 15.0 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_2 PF07724.9 ETO03185.1 - 0.0017 18.3 0.1 0.11 12.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) DUF258 PF03193.11 ETO03185.1 - 0.0017 17.5 0.0 0.0045 16.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MCM PF00493.18 ETO03185.1 - 0.0037 16.1 0.9 0.52 9.0 0.0 3.0 3 0 0 3 3 3 1 MCM2/3/5 family AAA_18 PF13238.1 ETO03185.1 - 0.0039 17.4 0.8 0.15 12.4 0.0 3.8 3 1 0 3 3 3 1 AAA domain DUF815 PF05673.8 ETO03185.1 - 0.0046 15.9 0.1 0.023 13.6 0.0 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF815) PduV-EutP PF10662.4 ETO03185.1 - 0.0047 16.4 0.1 0.017 14.5 0.0 1.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.12 ETO03185.1 - 0.0083 15.5 0.0 1.4 8.3 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 ETO03185.1 - 0.0091 16.0 0.0 0.34 10.9 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain T2SE PF00437.15 ETO03185.1 - 0.015 14.2 0.2 0.095 11.5 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_17 PF13207.1 ETO03185.1 - 0.02 15.7 2.6 0.088 13.6 0.1 3.2 3 1 0 4 4 2 0 AAA domain DUF2746 PF10874.3 ETO03185.1 - 0.029 14.5 1.8 0.11 12.6 0.1 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF2746) Miro PF08477.8 ETO03185.1 - 0.04 14.4 0.0 0.16 12.4 0.0 2.1 1 0 0 1 1 1 0 Miro-like protein Sigma54_activat PF00158.21 ETO03185.1 - 0.046 13.1 0.0 1.6 8.1 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 ETO03185.1 - 0.061 12.4 0.4 4.3 6.4 0.0 3.2 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 ETO03185.1 - 0.082 12.5 0.6 0.55 9.8 0.0 2.7 2 1 0 2 2 2 0 NACHT domain AAA_3 PF07726.6 ETO03185.1 - 0.095 12.3 0.0 12 5.5 0.0 3.3 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 ETO03185.1 - 0.22 11.7 2.3 2.3 8.4 0.0 3.3 3 0 0 3 3 2 0 RNA helicase AAA_23 PF13476.1 ETO03185.1 - 0.48 10.7 0.0 0.48 10.7 0.0 3.4 4 0 0 4 4 4 0 AAA domain Kelch_4 PF13418.1 ETO03187.1 - 0.00019 21.1 0.0 0.063 13.0 0.0 2.5 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO03187.1 - 0.00031 20.8 0.0 0.00071 19.6 0.0 1.6 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO03187.1 - 0.00073 19.6 0.0 0.028 14.5 0.0 2.5 1 1 1 2 2 2 1 Kelch motif Kelch_1 PF01344.20 ETO03187.1 - 0.00087 18.7 0.0 0.0052 16.3 0.0 2.1 2 0 0 2 2 2 1 Kelch motif DUF1599 PF07659.6 ETO03187.1 - 2.5 8.2 5.0 0.73 9.9 0.1 2.4 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1599) Pkinase PF00069.20 ETO03189.1 - 1.3e-10 40.8 0.0 1.8e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain CaM_binding PF07839.6 ETO03190.1 - 0.17 12.1 3.7 0.39 10.9 1.8 2.2 1 1 0 1 1 1 0 Plant calmodulin-binding domain DUF1231 PF06802.6 ETO03191.1 - 0.0098 14.8 3.0 0.012 14.5 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1231) Snapin_Pallidin PF14712.1 ETO03192.1 - 0.088 13.1 3.0 0.19 12.0 0.6 2.1 2 0 0 2 2 2 0 Snapin/Pallidin TPR_12 PF13424.1 ETO03193.1 - 7.2e-25 86.7 3.5 1.4e-14 53.7 0.4 1.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO03193.1 - 4.5e-09 35.5 2.6 4.5e-09 35.5 1.8 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO03193.1 - 2.8e-08 33.2 1.8 6.1e-08 32.2 0.6 1.9 2 0 0 2 2 2 1 TPR repeat TPR_10 PF13374.1 ETO03193.1 - 1.2e-06 28.2 0.4 2.7e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO03193.1 - 1.9e-06 27.1 4.0 1.9e-06 27.1 2.8 2.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO03193.1 - 2.4e-06 27.0 1.5 2.4e-06 27.0 1.0 2.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO03193.1 - 4.8e-06 25.9 0.1 1.2e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO03193.1 - 0.002 18.4 0.3 0.0078 16.6 0.2 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO03193.1 - 0.0023 18.0 1.4 0.0068 16.5 0.7 1.9 2 1 0 2 2 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 ETO03193.1 - 0.005 16.9 2.2 0.026 14.7 0.1 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO03193.1 - 0.0075 16.9 0.0 0.011 16.3 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF2225 PF09986.4 ETO03193.1 - 0.033 13.6 0.3 0.061 12.7 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) P21-Arc PF04062.9 ETO03193.1 - 0.035 13.8 0.1 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 ARP2/3 complex ARPC3 (21 kDa) subunit Sel1 PF08238.7 ETO03193.1 - 0.045 14.3 0.4 0.71 10.6 0.3 2.2 2 0 0 2 2 2 0 Sel1 repeat MIT PF04212.13 ETO03193.1 - 0.053 13.4 1.5 0.12 12.2 0.7 1.8 1 1 1 2 2 2 0 MIT (microtubule interacting and transport) domain Chordopox_A13L PF05961.6 ETO03193.1 - 0.44 10.5 7.4 0.99 9.3 1.2 2.5 2 0 0 2 2 2 0 Chordopoxvirus A13L protein C2 PF00168.25 ETO03194.1 - 9.9e-10 38.1 0.1 2.4e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain CAP_GLY PF01302.20 ETO03194.1 - 7.3e-08 32.0 0.3 2.5e-07 30.2 0.2 1.9 2 0 0 2 2 2 1 CAP-Gly domain Shisa PF13908.1 ETO03194.1 - 0.46 10.6 0.0 0.46 10.6 0.0 4.3 3 1 0 3 3 3 0 Wnt and FGF inhibitory regulator PUB PF09409.5 ETO03195.1 - 0.0048 16.6 0.3 0.02 14.6 0.2 2.0 1 1 0 1 1 1 1 PUB domain Peptidase_M44 PF03410.8 ETO03195.1 - 0.016 13.4 0.0 0.022 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein G1 Post_transc_reg PF13797.1 ETO03195.1 - 0.075 12.6 1.7 0.15 11.6 0.0 2.3 3 1 0 3 3 3 0 Post-transcriptional regulator Hex_IIIa PF02455.11 ETO03198.1 - 2.6 6.6 20.5 3.1 6.3 14.2 1.3 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) WD40 PF00400.27 ETO03199.1 - 4.4e-58 191.2 16.2 8.2e-15 54.0 0.3 4.7 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 ETO03199.1 - 1.2e-08 34.9 0.0 0.0014 18.3 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 ETO03199.1 - 7.3e-07 28.8 0.6 0.00011 21.7 0.1 2.4 1 1 1 2 2 2 2 PQQ-like domain DUF727 PF05303.7 ETO03199.1 - 2.3e-06 27.3 0.1 1.2 8.9 0.0 4.0 2 2 2 4 4 4 2 Protein of unknown function (DUF727) Gmad1 PF10647.4 ETO03199.1 - 3e-06 26.8 0.5 0.055 12.8 0.1 3.5 1 1 2 3 3 3 2 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.3 ETO03199.1 - 5.8e-05 21.4 2.3 0.29 9.1 0.0 3.4 1 1 2 3 3 3 2 Nucleoporin Nup120/160 PD40 PF07676.7 ETO03199.1 - 5.9e-05 22.6 5.4 5.2 6.8 0.0 4.4 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 ETO03199.1 - 0.00012 21.3 1.8 13 5.2 0.0 4.5 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature DUF1258 PF06869.7 ETO03199.1 - 0.004 16.2 0.2 2.6 7.0 0.0 3.2 1 1 3 4 4 4 1 Protein of unknown function (DUF1258) PQQ PF01011.16 ETO03199.1 - 0.0043 16.5 0.0 10 5.8 0.0 3.9 4 0 0 4 4 4 0 PQQ enzyme repeat Cytochrom_D1 PF02239.11 ETO03199.1 - 0.0071 14.6 0.0 1.2 7.3 0.0 2.0 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO03199.1 - 0.078 11.7 5.8 0.17 10.5 3.8 1.8 1 1 0 1 1 1 0 Nup133 N terminal like DUF3312 PF11768.3 ETO03199.1 - 0.088 11.0 0.0 2.5 6.2 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3312) Vps16_N PF04841.8 ETO03199.1 - 0.14 10.6 0.0 0.16 10.4 0.0 1.3 1 0 0 1 1 1 0 Vps16, N-terminal region NQRA_SLBB PF11973.3 ETO03199.1 - 0.16 12.3 2.2 90 3.5 0.1 3.6 3 0 0 3 3 3 0 NQRA C-terminal domain WD40 PF00400.27 ETO03200.1 - 7.1e-23 79.6 2.3 9.3e-11 41.1 0.1 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO03200.1 - 0.00099 17.3 0.4 0.12 10.4 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 HEAT PF02985.17 ETO03201.1 - 0.00023 21.0 0.0 0.008 16.1 0.0 2.7 2 0 0 2 2 2 1 HEAT repeat HEAT_2 PF13646.1 ETO03201.1 - 0.00091 19.4 0.0 0.23 11.7 0.0 2.1 1 1 1 2 2 2 2 HEAT repeats Imm16 PF15565.1 ETO03201.1 - 0.012 15.4 0.6 0.78 9.6 0.1 3.0 2 1 1 3 3 3 0 Immunity protein 16 DUF3554 PF12074.3 ETO03201.1 - 0.018 14.4 0.1 0.06 12.7 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3554) CLASP_N PF12348.3 ETO03201.1 - 0.022 14.1 0.2 0.079 12.2 0.0 1.8 1 1 1 2 2 2 0 CLASP N terminal MMS19_N PF14500.1 ETO03201.1 - 0.024 13.9 1.2 0.12 11.6 0.3 2.0 1 1 1 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.1 ETO03201.1 - 0.033 14.7 0.0 0.31 11.5 0.0 2.4 1 1 2 3 3 3 0 HEAT-like repeat V-ATPase_H_N PF03224.9 ETO03201.1 - 0.071 12.2 2.3 0.089 11.8 1.6 1.2 1 0 0 1 1 1 0 V-ATPase subunit H zf-AD PF07776.10 ETO03201.1 - 0.13 12.2 2.1 0.27 11.2 0.4 2.2 2 1 0 2 2 2 0 Zinc-finger associated domain (zf-AD) Ig_J_chain PF15097.1 ETO03201.1 - 0.22 11.1 2.7 0.42 10.1 0.1 2.1 1 1 1 2 2 2 0 Immunoglobulin J chain MBT PF02820.13 ETO03202.1 - 0.0079 16.0 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 mbt repeat 2_5_RNA_ligase2 PF13563.1 ETO03202.1 - 0.054 13.2 0.1 0.27 10.9 0.0 1.9 1 1 1 2 2 2 0 2'-5' RNA ligase superfamily Peptidase_M1 PF01433.15 ETO03203.1 - 8.1e-13 48.2 0.0 9.9e-13 47.9 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M1 DUF3819 PF12842.2 ETO03204.1 - 0.013 15.1 0.2 0.016 14.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) PPV_E2_N PF00508.12 ETO03204.1 - 0.053 12.6 0.0 0.064 12.4 0.0 1.2 1 0 0 1 1 1 0 E2 (early) protein, N terminal MOR2-PAG1_N PF14222.1 ETO03205.1 - 0.051 12.2 5.9 0.058 12.0 4.1 1.0 1 0 0 1 1 1 0 Cell morphogenesis N-terminal APG6 PF04111.7 ETO03205.1 - 0.053 12.5 23.0 0.066 12.2 15.9 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 CpeS PF09367.5 ETO03205.1 - 0.21 11.4 3.5 0.15 11.9 1.4 1.5 1 1 1 2 2 2 0 CpeS-like protein Membralin PF09746.4 ETO03205.1 - 0.45 9.4 7.3 0.49 9.3 5.0 1.1 1 0 0 1 1 1 0 Tumour-associated protein Hydantoinase_B PF02538.9 ETO03205.1 - 0.59 8.2 7.8 1.4 7.0 5.4 1.6 1 1 0 1 1 1 0 Hydantoinase B/oxoprolinase DUF4446 PF14584.1 ETO03205.1 - 0.87 9.4 11.2 0.83 9.4 6.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Reo_sigmaC PF04582.7 ETO03205.1 - 2.4 7.2 4.6 3.2 6.8 2.8 1.3 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Atg14 PF10186.4 ETO03205.1 - 2.4 7.0 19.8 3.6 6.4 13.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ALMT PF11744.3 ETO03205.1 - 5.1 5.6 10.6 5.8 5.4 7.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Mu-like_Pro PF10123.4 ETO03205.1 - 5.9 6.2 10.2 6.5 6.1 7.1 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein Peroxin-13_N PF04088.8 ETO03205.1 - 6.6 6.6 6.3 10 6.0 4.0 1.6 1 1 0 1 1 1 0 Peroxin 13, N-terminal region Allexi_40kDa PF05549.6 ETO03205.1 - 7.1 5.8 8.4 9.1 5.4 5.8 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein RP-C_C PF11800.3 ETO03205.1 - 7.2 6.2 8.3 8.9 5.9 5.7 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region LRS4 PF10422.4 ETO03205.1 - 8.3 5.6 22.3 11 5.2 15.4 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 SID-1_RNA_chan PF13965.1 ETO03205.1 - 9.6 4.2 7.0 13 3.8 4.9 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RabGAP-TBC PF00566.13 ETO03208.1 - 3.3e-20 72.4 1.9 1.8e-16 60.2 0.6 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Kelch_6 PF13964.1 ETO03209.1 - 1.5e-05 24.9 0.1 0.0089 16.1 0.0 2.6 2 1 0 2 2 2 2 Kelch motif Kelch_2 PF07646.10 ETO03209.1 - 2.3e-05 23.9 0.1 0.0041 16.8 0.0 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.20 ETO03209.1 - 2.8e-05 23.5 0.0 0.0029 17.1 0.0 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.1 ETO03209.1 - 8.1e-05 22.3 0.1 0.0096 15.6 0.0 2.4 1 1 1 2 2 2 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO03209.1 - 0.0074 16.4 0.1 0.049 13.8 0.0 2.3 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO03209.1 - 0.022 14.7 0.1 0.53 10.2 0.0 2.3 2 0 0 2 2 2 0 Kelch motif M20_dimer PF07687.9 ETO03211.1 - 3.5e-10 39.6 0.0 4e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase dimerisation domain Ribonuc_2-5A PF06479.7 ETO03211.1 - 0.042 13.6 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease 2-5A DUF1675 PF07897.6 ETO03212.1 - 0.38 10.5 5.1 0.42 10.4 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Seryl_tRNA_N PF02403.17 ETO03212.1 - 0.58 10.2 15.0 0.74 9.8 10.4 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain WHEP-TRS PF00458.15 ETO03212.1 - 0.82 9.3 8.2 1.7 8.3 5.6 1.7 1 1 1 2 2 2 0 WHEP-TRS domain TMF_DNA_bd PF12329.3 ETO03212.1 - 2.1 8.2 23.7 1.9e+02 1.9 2.5 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding IATP PF04568.7 ETO03212.1 - 3.2 7.8 10.8 4.1 7.5 7.5 1.2 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Ax_dynein_light PF10211.4 ETO03212.1 - 4.8 6.9 17.6 5 6.9 12.2 1.0 1 0 0 1 1 1 0 Axonemal dynein light chain rve PF00665.21 ETO03213.1 - 1.7e-14 53.9 0.4 2.5e-05 24.3 0.0 4.5 4 1 1 5 5 5 2 Integrase core domain zf-H2C2 PF09337.5 ETO03213.1 - 0.00035 19.9 0.1 0.00094 18.5 0.1 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger rve_3 PF13683.1 ETO03213.1 - 0.00063 19.2 0.0 0.0022 17.5 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 ETO03213.1 - 0.018 14.4 1.3 0.039 13.2 0.1 2.1 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Lyase_8_C PF02884.12 ETO03213.1 - 0.021 14.8 0.3 0.23 11.4 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide lyase family 8, C-terminal beta-sandwich domain DUF600 PF04634.7 ETO03213.1 - 0.025 14.5 3.1 0.37 10.7 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function, DUF600 zf-CCHC PF00098.18 ETO03214.1 - 0.0092 15.8 8.7 0.018 14.9 6.0 1.5 1 0 0 1 1 1 1 Zinc knuckle Exonuc_VII_L PF02601.10 ETO03214.1 - 0.1 11.7 5.4 0.15 11.2 3.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit WD40 PF00400.27 ETO03215.1 - 8.9e-09 34.9 0.2 6.7e-08 32.1 0.2 2.1 2 0 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO03215.1 - 0.069 11.2 0.0 0.079 11.0 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Rep_fac-A_3 PF08661.6 ETO03215.1 - 0.078 12.8 0.5 3 7.7 0.1 2.3 2 0 0 2 2 2 0 Replication factor A protein 3 NACHT PF05729.7 ETO03216.1 - 4.1e-10 39.5 0.0 8.4e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO03216.1 - 1.3e-05 25.4 0.1 1.3e-05 25.4 0.0 3.1 1 1 1 3 3 3 1 AAA domain AAA_22 PF13401.1 ETO03216.1 - 5.2e-05 23.3 0.1 0.0002 21.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 ETO03216.1 - 0.0013 18.2 0.0 0.0028 17.1 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 ETO03216.1 - 0.0043 17.8 3.1 0.02 15.6 0.0 3.0 2 2 1 3 3 3 1 AAA domain UPF0079 PF02367.12 ETO03216.1 - 0.0074 15.9 0.0 0.024 14.2 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 ATP_bind_2 PF03668.10 ETO03216.1 - 0.0086 15.1 0.1 0.056 12.5 0.0 2.0 2 0 0 2 2 2 1 P-loop ATPase protein family AAA PF00004.24 ETO03216.1 - 0.011 15.9 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 ETO03216.1 - 0.011 15.9 0.4 0.036 14.3 0.0 2.0 2 1 0 2 2 2 0 ABC transporter G-alpha PF00503.15 ETO03216.1 - 0.028 13.1 9.4 0.0079 14.9 3.7 2.0 1 1 1 2 2 2 0 G-protein alpha subunit Sigma54_activat PF00158.21 ETO03216.1 - 0.033 13.6 0.0 0.15 11.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 ETO03216.1 - 0.039 13.0 0.0 0.08 12.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 ETO03216.1 - 0.046 13.5 0.0 0.1 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 ETO03216.1 - 0.048 12.8 0.0 0.084 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 VirE PF05272.6 ETO03216.1 - 0.062 12.7 1.0 0.094 12.1 0.0 1.9 2 0 0 2 2 2 0 Virulence-associated protein E AAA_16 PF13191.1 ETO03216.1 - 0.11 12.4 0.3 1.8 8.5 0.0 2.4 1 1 1 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 ETO03216.1 - 0.11 11.9 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 ETO03216.1 - 0.15 12.2 2.9 0.21 11.7 0.2 2.7 2 1 0 2 2 2 0 RNA helicase DUF502 PF04367.8 ETO03217.1 - 0.036 13.8 0.2 3.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF502) GIDA PF01134.17 ETO03217.1 - 0.16 10.8 0.7 0.19 10.5 0.5 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF2540 PF10802.3 ETO03217.1 - 1.3 8.7 4.5 0.23 11.1 0.4 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2540) Kelch_6 PF13964.1 ETO03218.1 - 0.00024 21.1 2.5 0.25 11.6 0.1 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 ETO03218.1 - 0.00054 19.8 4.0 0.21 11.6 0.1 3.5 3 1 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 ETO03218.1 - 0.00061 19.4 4.1 1.2 9.0 0.1 4.1 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO03218.1 - 0.01 15.6 2.7 0.13 12.0 0.0 3.1 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO03218.1 - 0.011 15.1 2.2 0.46 10.0 0.2 3.4 3 0 0 3 3 3 0 Kelch motif Kelch_3 PF13415.1 ETO03218.1 - 0.12 12.5 0.6 2.4 8.4 0.0 3.0 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO03220.1 - 2.7e-06 27.3 2.8 0.077 13.2 0.1 3.3 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO03220.1 - 0.00014 21.5 0.1 0.11 12.3 0.0 3.7 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO03220.1 - 0.00017 21.0 7.0 0.02 14.4 0.3 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 ETO03220.1 - 0.096 12.8 0.0 7 6.9 0.0 2.7 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO03220.1 - 0.45 10.5 3.6 1.5 8.8 0.3 3.1 3 0 0 3 3 3 0 Kelch motif WD40 PF00400.27 ETO03221.1 - 1.8e-12 46.5 0.0 5.5e-08 32.3 0.0 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO03221.1 - 0.027 12.6 0.0 0.052 11.6 0.0 1.4 1 1 0 1 1 1 0 Nucleoporin Nup120/160 WD40 PF00400.27 ETO03222.1 - 1.4e-62 205.5 14.2 2.3e-13 49.4 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat PD40 PF07676.7 ETO03222.1 - 1.1e-06 28.1 11.4 0.89 9.2 0.0 6.2 6 0 0 6 6 6 3 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO03222.1 - 2.8e-06 25.7 3.5 0.059 11.4 0.8 4.6 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Proteasome_A_N PF10584.4 ETO03222.1 - 0.00026 20.2 4.7 1.9 7.8 0.0 5.3 5 0 0 5 5 5 2 Proteasome subunit A N-terminal signature DPPIV_N PF00930.16 ETO03222.1 - 0.00063 18.4 0.1 1.7 7.1 0.0 3.5 1 1 1 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Kelch_3 PF13415.1 ETO03222.1 - 0.0015 18.6 0.1 0.017 15.2 0.0 2.9 3 0 0 3 3 3 1 Galactose oxidase, central domain Gmad1 PF10647.4 ETO03222.1 - 0.0098 15.3 0.0 0.027 13.8 0.0 1.7 1 1 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Cytochrom_D1 PF02239.11 ETO03222.1 - 0.013 13.8 7.1 0.88 7.7 0.0 3.5 2 1 2 4 4 4 0 Cytochrome D1 heme domain Resistin PF06954.6 ETO03222.1 - 0.013 15.7 0.0 8.8 6.6 0.0 3.4 1 1 2 3 3 3 0 Resistin Kelch_1 PF01344.20 ETO03222.1 - 0.02 14.4 0.1 0.02 14.4 0.0 3.7 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.1 ETO03222.1 - 0.037 13.7 2.6 0.18 11.6 0.0 3.6 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO03222.1 - 0.058 13.3 0.3 0.89 9.5 0.0 3.0 3 0 0 3 3 3 0 Kelch motif Nucleoporin_N PF08801.6 ETO03222.1 - 0.077 11.7 13.1 7 5.2 2.5 5.2 1 1 3 4 4 4 0 Nup133 N terminal like WD40 PF00400.27 ETO03223.1 - 1.6e-83 271.8 23.0 1.6e-13 49.9 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO03223.1 - 9.5e-18 64.6 4.1 5.2e-05 23.0 0.0 3.5 1 1 4 5 5 5 5 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO03223.1 - 3.8e-09 35.2 3.1 0.00021 19.5 0.0 4.0 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO03223.1 - 5.1e-09 34.9 1.1 0.00034 19.0 0.0 3.9 1 1 2 4 4 4 3 Cytochrome D1 heme domain PD40 PF07676.7 ETO03223.1 - 8.1e-09 34.9 13.2 0.3 10.7 0.1 7.1 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO03223.1 - 3.6e-06 26.6 0.1 2.2e-05 24.0 0.0 2.4 1 1 0 2 2 2 1 PQQ-like domain Coatomer_WDAD PF04053.9 ETO03223.1 - 0.0001 21.2 3.0 0.074 11.8 0.4 2.9 1 1 1 2 2 2 2 Coatomer WD associated region SGL PF08450.7 ETO03223.1 - 0.00016 21.1 1.0 0.57 9.5 0.2 2.9 1 1 1 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Resistin PF06954.6 ETO03223.1 - 0.00018 21.6 0.7 1 9.7 0.1 4.2 2 2 2 5 5 5 1 Resistin Proteasome_A_N PF10584.4 ETO03223.1 - 0.00022 20.4 8.0 7.8 5.9 0.1 5.5 5 0 0 5 5 5 2 Proteasome subunit A N-terminal signature Nucleoporin_N PF08801.6 ETO03223.1 - 0.002 16.9 9.0 0.67 8.6 0.1 4.2 1 1 2 4 4 4 1 Nup133 N terminal like PQQ PF01011.16 ETO03223.1 - 0.043 13.3 0.1 4.8 6.9 0.0 3.5 4 0 0 4 4 4 0 PQQ enzyme repeat TFIIIC_delta PF12657.2 ETO03223.1 - 0.28 10.8 6.2 0.71 9.5 0.1 3.1 3 0 0 3 3 3 0 Transcription factor IIIC subunit delta N-term VWA_2 PF13519.1 ETO03224.1 - 0.0046 17.0 0.0 0.0055 16.8 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Polysacc_deac_1 PF01522.16 ETO03224.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide deacetylase Daxx PF03344.10 ETO03225.1 - 1.1 7.7 19.8 1.1 7.6 13.7 1.0 1 0 0 1 1 1 0 Daxx Family F-protein PF00469.15 ETO03226.1 - 0.55 9.5 5.0 1.1 8.5 3.5 1.5 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef SprA-related PF12118.3 ETO03226.1 - 0.72 9.1 10.9 0.99 8.6 7.6 1.1 1 0 0 1 1 1 0 SprA-related family DUF912 PF06024.7 ETO03226.1 - 4.3 7.4 9.8 4.5 7.3 0.3 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SSP160 PF06933.6 ETO03226.1 - 5.1 4.9 20.3 0.035 12.0 6.1 2.0 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 PBS_linker_poly PF00427.16 ETO03227.1 - 0.028 14.1 0.1 0.042 13.5 0.0 1.3 1 1 0 1 1 1 0 Phycobilisome Linker polypeptide Flu_PB1 PF00602.12 ETO03227.1 - 0.089 10.5 0.0 0.095 10.4 0.0 1.0 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB1 PMAIP1 PF15150.1 ETO03227.1 - 4.2 7.2 5.3 8.1 6.2 0.0 2.7 3 0 0 3 3 3 0 Phorbol-12-myristate-13-acetate-induced DUF4541 PF15074.1 ETO03228.1 - 0.092 13.2 0.5 0.092 13.2 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4541) HEAT_2 PF13646.1 ETO03229.1 - 1.8e-20 72.9 0.0 7.4e-09 35.7 0.0 5.0 3 2 1 4 4 4 4 HEAT repeats HEAT PF02985.17 ETO03229.1 - 4.3e-18 63.7 0.0 0.00079 19.3 0.0 7.8 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.1 ETO03229.1 - 4.6e-14 52.4 0.0 0.0084 16.5 0.0 6.3 6 0 0 6 6 6 3 HEAT-like repeat Ank_2 PF12796.2 ETO03229.1 - 5.2e-09 36.3 0.1 3.6e-08 33.6 0.0 2.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO03229.1 - 1.4e-07 31.0 0.0 0.014 15.6 0.0 3.5 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.25 ETO03229.1 - 4.1e-07 29.4 0.0 0.0014 18.2 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 ETO03229.1 - 5.9e-07 29.8 0.3 5.6e-06 26.7 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO03229.1 - 0.0015 18.6 0.1 0.0096 16.1 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Choline_sulf_C PF12411.3 ETO03229.1 - 0.13 12.1 0.5 0.44 10.4 0.2 2.1 2 0 0 2 2 2 0 Choline sulfatase enzyme C terminal Kelch_5 PF13854.1 ETO03230.1 - 0.0046 16.8 0.2 1.7 8.7 0.0 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.1 ETO03230.1 - 0.038 14.1 0.6 2.1 8.6 0.1 3.1 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.10 ETO03230.1 - 0.082 12.7 0.9 3.9 7.3 0.1 3.3 3 0 0 3 3 3 0 Kelch motif VCBS PF13517.1 ETO03230.1 - 0.98 9.8 3.0 2.3 8.6 1.4 2.2 2 1 1 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF960 PF06124.6 ETO03231.1 - 0.83 9.9 4.9 2.2 8.5 3.1 2.0 1 1 1 2 2 2 0 Staphylococcal protein of unknown function (DUF960) SpoVR PF04293.8 ETO03232.1 - 0.0027 16.1 1.4 0.0033 15.8 1.0 1.1 1 0 0 1 1 1 1 SpoVR like protein Atrophin-1 PF03154.10 ETO03232.1 - 0.058 11.5 2.8 0.067 11.3 2.0 1.0 1 0 0 1 1 1 0 Atrophin-1 family Syntaxin PF00804.20 ETO03232.1 - 0.091 12.9 4.0 0.15 12.2 2.8 1.3 1 0 0 1 1 1 0 Syntaxin APG6 PF04111.7 ETO03232.1 - 0.1 11.6 3.5 0.12 11.3 2.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Spore_III_AB PF09548.5 ETO03232.1 - 0.15 11.8 5.2 0.23 11.1 3.6 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) efb-c PF12199.3 ETO03234.1 - 0.58 10.0 3.0 16 5.4 0.2 2.3 2 0 0 2 2 2 0 Extracellular fibrinogen binding protein C terminal NACHT PF05729.7 ETO03236.1 - 0.00094 18.8 1.7 0.019 14.6 0.2 2.1 2 0 0 2 2 2 2 NACHT domain DUF1444 PF07285.6 ETO03236.1 - 0.0083 15.4 0.1 0.4 9.9 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1444) zf-TRAF PF02176.13 ETO03238.1 - 5.6e-07 29.8 2.4 2.7e-06 27.6 1.7 2.3 1 0 0 1 1 1 1 TRAF-type zinc finger CENP-T PF15511.1 ETO03238.1 - 0.55 9.4 9.9 1.4 8.0 6.9 1.6 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T zf-Tim10_DDP PF02953.10 ETO03239.1 - 0.035 13.4 0.2 0.12 11.6 0.2 1.9 1 0 0 1 1 1 0 Tim10/DDP family zinc finger DUF3722 PF12519.3 ETO03240.1 - 0.025 13.8 0.1 0.042 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3722) BSP_II PF05432.6 ETO03244.1 - 0.029 13.6 9.7 0.041 13.1 6.7 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Afi1 PF07792.7 ETO03244.1 - 0.037 14.0 3.3 0.093 12.7 1.1 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Sporozoite_P67 PF05642.6 ETO03244.1 - 0.73 7.6 5.1 1.2 6.9 3.5 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM176 PF14851.1 ETO03244.1 - 1.6 8.3 5.9 3.3 7.3 4.1 1.4 1 0 0 1 1 1 0 FAM176 family Sec7 PF01369.15 ETO03245.1 - 1.3e-53 181.4 0.7 2.6e-53 180.5 0.5 1.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 ETO03245.1 - 3.3e-12 46.1 0.1 9e-12 44.7 0.1 1.8 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal TPR_11 PF13414.1 ETO03246.1 - 9.2e-14 50.8 1.2 7.5e-13 47.9 0.3 2.2 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 ETO03246.1 - 3e-10 39.2 3.8 1.4e-05 24.4 0.3 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO03246.1 - 1.4e-08 34.0 1.4 0.002 17.9 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat Sec7_N PF12783.2 ETO03246.1 - 1.2e-07 31.3 2.7 1.2e-07 31.3 1.8 3.5 3 2 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal TPR_19 PF14559.1 ETO03246.1 - 0.00057 20.1 0.0 0.0015 18.8 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO03246.1 - 0.0009 19.1 0.7 0.012 15.5 0.2 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO03246.1 - 0.0029 17.2 1.9 0.028 14.2 0.1 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO03246.1 - 0.012 16.2 0.0 0.031 14.9 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.1 ETO03246.1 - 0.026 14.6 0.8 0.096 12.9 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETO03246.1 - 0.049 14.2 0.0 0.21 12.3 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 ETO03246.1 - 0.15 12.1 5.2 0.19 11.8 1.1 2.8 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Sulfotransfer_3 PF13469.1 ETO03247.1 - 4.3e-08 34.2 0.5 6.7e-08 33.6 0.3 1.3 1 0 0 1 1 1 1 Sulfotransferase family DUF1981 PF09324.5 ETO03250.1 - 6e-27 92.9 5.2 1.7e-26 91.5 0.0 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF1981) Las1 PF04031.8 ETO03251.1 - 0.073 12.7 0.0 0.11 12.1 0.0 1.3 1 1 0 1 1 1 0 Las1-like WD40 PF00400.27 ETO03252.1 - 8.9e-22 76.1 9.0 1.8e-09 37.1 1.7 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO03252.1 - 0.00015 20.0 1.5 0.0084 14.2 0.1 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Cytokin-bind PF09265.5 ETO03252.1 - 0.021 13.9 0.1 0.023 13.8 0.0 1.1 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding eIF2A PF08662.6 ETO03252.1 - 0.057 13.1 0.9 3.4 7.3 0.1 2.1 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A TPR_12 PF13424.1 ETO03253.1 - 2.7e-66 219.4 15.4 2.8e-22 78.4 0.2 3.0 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO03253.1 - 9.6e-26 88.9 0.0 2.2e-08 33.7 0.0 3.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO03253.1 - 1.1e-25 88.0 16.4 1.5e-08 33.9 0.3 3.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO03253.1 - 6.6e-23 78.6 2.7 5.9e-08 31.9 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO03253.1 - 6.6e-23 80.1 5.6 1.6e-14 53.2 0.5 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 ETO03253.1 - 1.4e-20 71.4 11.8 1.7e-06 27.4 0.7 3.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO03253.1 - 5.1e-15 54.0 20.0 3.6e-05 23.2 0.3 3.5 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO03253.1 - 8.6e-11 41.1 7.5 0.0011 19.0 0.1 4.3 5 1 0 5 5 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO03253.1 - 4.8e-09 36.0 0.0 0.37 11.5 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO03253.1 - 1.6e-06 28.6 0.0 0.00071 20.1 0.0 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.13 ETO03253.1 - 7.1e-06 25.8 7.3 0.082 12.8 0.1 3.1 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain SNAP PF14938.1 ETO03253.1 - 6.5e-05 22.2 0.1 0.0001 21.5 0.1 1.3 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP DUF3856 PF12968.2 ETO03253.1 - 0.00019 21.2 0.7 0.019 14.7 0.1 2.2 1 1 1 2 2 2 2 Domain of Unknown Function (DUF3856) Apc3 PF12895.2 ETO03253.1 - 0.00021 21.3 2.6 0.063 13.4 0.1 2.2 1 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 ETO03253.1 - 0.00022 20.9 1.8 0.061 13.3 0.1 3.1 3 0 0 3 3 3 1 PPR repeat TPR_6 PF13174.1 ETO03253.1 - 0.00023 21.3 1.0 1 9.9 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO03253.1 - 0.0013 19.0 0.2 0.15 12.4 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF2977 PF11192.3 ETO03253.1 - 0.0055 16.4 0.0 1.5 8.6 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2977) TPR_3 PF07720.7 ETO03253.1 - 0.0057 16.4 6.4 0.48 10.2 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF2225 PF09986.4 ETO03253.1 - 0.012 15.0 1.1 0.063 12.7 0.1 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Mob_Pre PF01076.14 ETO03253.1 - 0.013 15.1 0.8 0.016 14.8 0.2 1.4 2 0 0 2 2 2 0 Plasmid recombination enzyme RPN7 PF10602.4 ETO03253.1 - 0.017 14.5 3.2 2.2 7.6 0.3 2.6 1 1 1 2 2 2 0 26S proteasome subunit RPN7 ATP-synt_E_2 PF08112.6 ETO03253.1 - 0.021 14.8 0.3 7.3 6.7 0.0 2.4 2 0 0 2 2 2 0 ATP synthase epsilon subunit Aldo_ket_red PF00248.16 ETO03253.1 - 0.024 13.4 0.3 0.034 12.9 0.1 1.2 1 1 0 1 1 1 0 Aldo/keto reductase family Fis1_TPR_C PF14853.1 ETO03253.1 - 0.095 12.6 6.4 5.2 7.0 0.3 3.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DUF357 PF04010.8 ETO03253.1 - 0.25 11.0 4.9 1.7 8.4 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF357) FAM176 PF14851.1 ETO03254.1 - 0.0058 16.3 0.6 0.0073 15.9 0.4 1.1 1 0 0 1 1 1 1 FAM176 family DUF3153 PF11353.3 ETO03254.1 - 0.016 14.6 1.9 0.84 9.0 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3153) rRNA_processing PF08524.6 ETO03254.1 - 0.025 14.3 11.0 0.036 13.8 7.6 1.2 1 0 0 1 1 1 0 rRNA processing Gemini_AL2 PF01440.11 ETO03254.1 - 0.042 13.9 0.1 0.051 13.6 0.1 1.2 1 0 0 1 1 1 0 Geminivirus AL2 protein Eapp_C PF10238.4 ETO03254.1 - 0.054 13.3 0.8 0.068 13.0 0.6 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein c-SKI_SMAD_bind PF08782.5 ETO03254.1 - 0.056 13.5 1.4 0.076 13.1 0.6 1.5 1 1 0 1 1 1 0 c-SKI Smad4 binding domain Apis_Csd PF11671.3 ETO03254.1 - 0.062 13.0 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 Complementary sex determiner protein RNase_H2-Ydr279 PF09468.5 ETO03254.1 - 0.13 11.4 4.6 0.15 11.1 3.2 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) HSP90 PF00183.13 ETO03254.1 - 0.54 8.5 8.1 0.57 8.4 5.6 1.0 1 0 0 1 1 1 0 Hsp90 protein Peptidase_S49_N PF08496.5 ETO03254.1 - 0.75 9.5 5.1 0.88 9.3 3.6 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TMF_DNA_bd PF12329.3 ETO03255.1 - 0.0068 16.1 51.0 0.052 13.3 9.4 4.1 1 1 4 5 5 5 3 TATA element modulatory factor 1 DNA binding Cep57_CLD_2 PF14197.1 ETO03255.1 - 0.0092 15.9 6.0 0.0092 15.9 4.2 3.6 2 1 1 3 3 3 1 Centrosome localisation domain of PPC89 Filament PF00038.16 ETO03255.1 - 0.016 14.6 40.1 0.06 12.8 8.0 2.2 1 1 1 2 2 2 0 Intermediate filament protein Tropomyosin_1 PF12718.2 ETO03255.1 - 0.02 14.7 48.8 0.022 14.6 27.3 3.2 1 1 1 2 2 1 0 Tropomyosin like AAA_27 PF13514.1 ETO03255.1 - 0.022 12.5 26.7 0.028 12.1 18.5 1.1 1 0 0 1 1 1 0 AAA domain GAS PF13851.1 ETO03255.1 - 0.027 13.6 51.6 0.29 10.3 12.3 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1633 PF07794.6 ETO03255.1 - 0.037 11.9 5.4 0.043 11.7 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) TMCO5 PF14992.1 ETO03255.1 - 0.042 12.9 28.3 0.055 12.6 19.6 1.2 1 0 0 1 1 1 0 TMCO5 family TPR_MLP1_2 PF07926.7 ETO03255.1 - 0.14 11.9 47.4 0.13 11.9 17.6 3.0 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.6 ETO03255.1 - 0.22 11.3 38.6 0.11 12.3 12.9 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 ETO03255.1 - 0.23 10.6 10.4 0.087 11.9 2.7 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Mitofilin PF09731.4 ETO03255.1 - 0.25 9.9 29.2 0.33 9.5 20.2 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF3584 PF12128.3 ETO03255.1 - 0.29 8.3 35.8 0.4 7.9 24.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ADIP PF11559.3 ETO03255.1 - 0.36 10.7 47.0 0.56 10.1 10.3 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding HOOK PF05622.7 ETO03255.1 - 0.5 8.1 35.2 0.6 7.8 24.4 1.0 1 0 0 1 1 1 0 HOOK protein CCDC155 PF14662.1 ETO03255.1 - 0.57 9.7 39.0 6 6.4 26.5 2.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 Tropomyosin PF00261.15 ETO03255.1 - 2.6 7.0 39.4 0.012 14.7 13.2 2.1 1 1 1 2 2 2 0 Tropomyosin Seryl_tRNA_N PF02403.17 ETO03255.1 - 2.7 8.0 42.0 0.19 11.7 12.4 3.1 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF3450 PF11932.3 ETO03255.1 - 2.9 7.1 35.8 26 3.9 14.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) SOBP PF15279.1 ETO03255.1 - 3.9 7.7 13.0 4.8 7.4 9.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein AphA_like PF14557.1 ETO03255.1 - 4.4 6.8 6.7 23 4.4 1.1 2.7 1 1 2 3 3 3 0 Putative AphA-like transcriptional regulator Rootletin PF15035.1 ETO03255.1 - 4.9 7.0 39.0 0.26 11.2 7.4 2.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion CENP-F_leu_zip PF10473.4 ETO03255.1 - 5.4 6.8 44.8 0.15 11.9 17.9 2.4 1 1 1 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF812 PF05667.6 ETO03255.1 - 5.8 5.2 38.4 4.3 5.7 9.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Atg14 PF10186.4 ETO03255.1 - 5.9 5.7 42.5 1.6 7.6 19.9 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 bZIP_2 PF07716.10 ETO03255.1 - 6.3 6.7 32.8 3.3 7.5 0.7 3.6 3 0 0 3 3 3 0 Basic region leucine zipper Tox-ODYAM1 PF15642.1 ETO03255.1 - 6.9 5.2 24.1 9.1 4.8 16.7 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Mnd1 PF03962.10 ETO03255.1 - 8.1 6.0 42.0 2 8.0 5.2 2.6 1 1 1 2 2 2 0 Mnd1 family DUF724 PF05266.9 ETO03255.1 - 9.7 5.7 42.1 0.56 9.8 11.8 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF724) DUF1461 PF07314.6 ETO03255.1 - 9.7 5.8 9.3 0.32 10.6 2.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) Ribosomal_S4e PF00900.15 ETO03256.1 - 0.04 13.5 1.4 0.15 11.7 0.1 2.4 2 1 1 3 3 3 0 Ribosomal family S4e RE_LlaJI PF09563.5 ETO03256.1 - 0.051 12.2 0.0 0.051 12.2 0.0 1.2 1 0 0 1 1 1 0 LlaJI restriction endonuclease UQ_con PF00179.21 ETO03257.1 - 0.0017 17.8 0.1 0.003 16.9 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Arm PF00514.18 ETO03258.1 - 9.4e-26 88.7 15.4 1.2e-07 31.2 0.0 5.7 6 0 0 6 6 6 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 ETO03258.1 - 2e-08 34.3 4.7 0.0031 17.7 0.2 3.7 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 ETO03258.1 - 2.3e-08 34.2 11.4 0.0032 17.8 0.2 4.9 3 1 2 5 5 5 4 HEAT-like repeat HEAT PF02985.17 ETO03258.1 - 3.4e-05 23.5 7.8 0.024 14.6 0.0 5.4 6 0 0 6 6 6 1 HEAT repeat Proteasom_PSMB PF10508.4 ETO03258.1 - 6.6e-05 21.3 1.6 0.00012 20.4 0.2 1.9 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit Cnd1 PF12717.2 ETO03258.1 - 0.0043 16.9 0.1 0.028 14.2 0.0 2.3 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Vps5 PF09325.5 ETO03258.1 - 0.065 12.4 0.3 0.12 11.6 0.2 1.3 1 0 0 1 1 1 0 Vps5 C terminal like V-ATPase_H_N PF03224.9 ETO03258.1 - 0.088 11.9 1.5 4.3 6.3 1.0 2.5 1 1 0 1 1 1 0 V-ATPase subunit H V-ATPase_H_C PF11698.3 ETO03258.1 - 0.11 12.4 0.2 1.1 9.1 0.1 2.2 2 0 0 2 2 2 0 V-ATPase subunit H DUF3731 PF12531.3 ETO03258.1 - 0.15 11.5 0.4 18 4.7 0.0 2.9 2 1 1 3 3 3 0 DNA-K related protein SdrG_C_C PF10425.4 ETO03259.1 - 0.0027 17.6 0.6 0.043 13.7 0.0 2.4 2 0 0 2 2 2 1 C-terminus of bacterial fibrinogen-binding adhesin DOMON PF03351.12 ETO03260.1 - 0.0019 18.1 0.3 1.6 8.6 0.0 2.3 2 0 0 2 2 2 2 DOMON domain DUF1361 PF07099.6 ETO03261.1 - 0.085 12.6 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1361) IPK PF03770.11 ETO03262.1 - 0.0074 15.9 2.0 0.016 14.8 0.3 1.8 1 1 1 2 2 2 1 Inositol polyphosphate kinase Imm16 PF15565.1 ETO03262.1 - 0.016 15.0 0.1 0.25 11.1 0.1 2.2 1 1 0 2 2 2 0 Immunity protein 16 MA3 PF02847.12 ETO03262.1 - 0.03 14.0 1.8 0.068 12.8 1.3 1.9 1 1 0 1 1 1 0 MA3 domain Hydrolase_3 PF08282.7 ETO03262.1 - 0.042 13.4 4.8 0.048 13.2 3.3 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase OS-D PF03392.8 ETO03262.1 - 0.055 13.4 4.7 0.065 13.2 2.7 1.6 1 1 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D DUF4485 PF14846.1 ETO03262.1 - 0.11 12.1 1.6 1.1 8.9 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4485) zf-P11 PF03854.9 ETO03262.1 - 0.66 9.4 3.0 1.6 8.2 0.2 2.3 2 0 0 2 2 2 0 P-11 zinc finger zf-TRAF PF02176.13 ETO03263.1 - 1.6e-06 28.3 5.3 5.9e-06 26.5 3.6 2.0 1 1 0 1 1 1 1 TRAF-type zinc finger Sina PF03145.11 ETO03263.1 - 0.092 12.3 10.0 0.74 9.4 0.1 2.9 1 1 2 3 3 3 0 Seven in absentia protein family DUF399 PF04187.8 ETO03264.1 - 0.0022 17.5 0.7 0.0036 16.8 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF399 DUF445 PF04286.7 ETO03265.1 - 0.039 13.4 0.1 0.13 11.8 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF445) DUF3484 PF11983.3 ETO03265.1 - 0.09 13.6 0.2 0.22 12.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3484) RRF_GI PF12614.3 ETO03265.1 - 0.1 12.4 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Ribosome recycling factor DUF2838 PF10998.3 ETO03265.1 - 0.21 11.4 3.9 4.2 7.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2838) SPARC_Ca_bdg PF10591.4 ETO03266.1 - 0.038 14.0 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Cactin_mid PF10312.4 ETO03266.1 - 0.086 12.0 0.1 0.086 12.0 0.1 1.2 1 0 0 1 1 1 0 Conserved mid region of cactin TPR_12 PF13424.1 ETO03267.1 - 4.5e-59 196.3 8.6 8.6e-25 86.4 0.4 3.2 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO03267.1 - 7.6e-40 133.7 0.0 1.3e-09 37.7 0.0 4.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO03267.1 - 4e-38 128.9 32.2 3.5e-13 48.9 3.3 2.9 1 1 3 4 4 4 4 TPR repeat TPR_7 PF13176.1 ETO03267.1 - 4e-33 110.5 1.3 2.6e-08 33.0 0.0 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO03267.1 - 1.5e-28 97.2 24.6 2.5e-08 33.1 0.4 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO03267.1 - 6.8e-22 75.5 16.7 2e-05 24.1 0.2 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO03267.1 - 9.7e-19 65.6 32.3 1e-05 24.9 1.4 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETO03267.1 - 1.1e-16 59.6 10.0 0.0013 18.7 0.1 4.8 3 1 1 4 4 4 4 Tetratricopeptide repeat Apc3 PF12895.2 ETO03267.1 - 9.2e-08 32.1 13.4 0.03 14.4 0.2 3.5 1 1 3 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 ETO03267.1 - 1.3e-07 32.0 0.0 0.093 13.4 0.0 3.1 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO03267.1 - 2.8e-07 30.5 0.0 0.42 11.3 0.0 4.1 1 1 3 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.7 ETO03267.1 - 3.1e-07 30.0 16.0 0.027 14.2 0.2 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat PPR PF01535.15 ETO03267.1 - 6.9e-06 25.7 7.5 0.34 10.9 0.1 4.0 4 0 0 4 4 4 2 PPR repeat DUF2642 PF10842.3 ETO03267.1 - 0.0014 18.0 0.0 9.1 5.8 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2642) TPR_6 PF13174.1 ETO03267.1 - 0.0025 18.1 3.3 11 6.7 0.0 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETO03267.1 - 0.0028 17.9 1.0 1 9.7 0.1 3.2 1 1 3 4 4 4 1 Tetratricopeptide repeat Ten1_2 PF15490.1 ETO03267.1 - 0.0037 16.8 0.0 2.4 7.7 0.0 3.4 1 1 3 4 4 4 1 Telomere-capping, CST complex subunit DUF627 PF04781.7 ETO03267.1 - 0.0051 16.4 11.7 0.36 10.4 0.5 4.0 1 1 3 4 4 4 1 Protein of unknown function (DUF627) DUF357 PF04010.8 ETO03267.1 - 0.012 15.3 8.5 0.97 9.1 0.8 3.9 1 1 3 4 4 4 0 Protein of unknown function (DUF357) Mob_Pre PF01076.14 ETO03267.1 - 0.015 14.9 2.7 0.58 9.7 0.2 2.2 1 1 2 3 3 3 0 Plasmid recombination enzyme RPN7 PF10602.4 ETO03267.1 - 0.021 14.1 6.6 0.28 10.5 0.4 3.4 1 1 0 3 3 3 0 26S proteasome subunit RPN7 FATC PF02260.15 ETO03267.1 - 0.034 13.5 5.7 0.64 9.5 0.1 3.4 4 0 0 4 4 4 0 FATC domain Pep3_Vps18 PF05131.9 ETO03267.1 - 0.036 13.5 2.5 9.7 5.6 0.0 3.7 4 0 0 4 4 4 0 Pep3/Vps18/deep orange family 14-3-3 PF00244.15 ETO03267.1 - 0.038 13.0 1.9 0.11 11.5 0.1 2.1 1 1 1 2 2 2 0 14-3-3 protein Sel1 PF08238.7 ETO03267.1 - 0.04 14.5 9.1 2.8 8.7 0.1 4.0 4 1 0 4 4 4 0 Sel1 repeat Musclin PF11037.3 ETO03267.1 - 0.042 13.4 0.0 2.6 7.6 0.0 2.9 3 0 0 3 3 3 0 Insulin-resistance promoting peptide in skeletal muscle DUF386 PF04074.7 ETO03267.1 - 0.053 13.0 3.7 0.9 9.0 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF386) Sipho_tail PF05709.6 ETO03267.1 - 0.079 12.0 0.4 1.4 8.0 0.0 2.0 2 0 0 2 2 2 0 Phage tail protein DUF3450 PF11932.3 ETO03267.1 - 0.14 11.3 4.9 8.7 5.5 0.0 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) PPR_2 PF13041.1 ETO03267.1 - 0.18 11.8 3.9 11 6.1 0.1 3.4 3 0 0 3 3 3 0 PPR repeat family MCM_N PF14551.1 ETO03267.1 - 0.23 11.9 3.2 8 6.9 2.2 2.3 1 1 0 1 1 1 0 MCM N-terminal domain MIT PF04212.13 ETO03267.1 - 0.4 10.5 11.9 4.5 7.2 0.2 3.9 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain ATP-synt_E_2 PF08112.6 ETO03267.1 - 1.4 9.0 10.3 3.1 7.9 0.0 3.8 4 0 0 4 4 4 0 ATP synthase epsilon subunit Kelch_4 PF13418.1 ETO03268.1 - 0.00019 21.1 0.1 0.044 13.5 0.1 2.4 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO03268.1 - 0.00027 20.5 0.1 0.026 14.2 0.1 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.20 ETO03268.1 - 0.0004 19.8 1.8 0.023 14.2 1.1 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO03268.1 - 0.0026 17.8 0.2 0.012 15.7 0.0 2.2 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO03268.1 - 0.011 15.9 2.8 1.6 9.0 0.6 2.8 2 1 1 3 3 3 0 Kelch motif DUF1947 PF09183.5 ETO03269.1 - 0.075 12.7 0.1 0.27 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) SelP_N PF04592.9 ETO03269.1 - 5.3 6.3 19.2 7.7 5.8 13.3 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FAM194 PF14977.1 ETO03270.1 - 0.013 14.4 1.2 0.016 14.2 0.8 1.0 1 0 0 1 1 1 0 FAM194 protein GCIP PF13324.1 ETO03271.1 - 0.0067 15.6 5.6 0.009 15.2 3.9 1.1 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Hydrolase_like2 PF13246.1 ETO03271.1 - 0.056 13.4 1.6 0.078 12.9 0.6 1.6 2 0 0 2 2 2 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Ribosomal_S15 PF00312.17 ETO03271.1 - 0.13 12.0 4.1 0.13 12.0 1.7 1.9 1 1 1 2 2 2 0 Ribosomal protein S15 PDGF_N PF04692.8 ETO03271.1 - 0.14 12.6 2.7 0.25 11.8 1.5 2.0 1 1 0 1 1 1 0 Platelet-derived growth factor, N terminal region Adaptin_binding PF10199.4 ETO03271.1 - 3.5 7.9 13.9 5.8 7.1 9.7 1.6 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 POX PF07526.6 ETO03271.1 - 6.7 6.9 7.6 2.8 8.1 3.4 1.7 1 1 1 2 2 2 0 Associated with HOX Mitofilin PF09731.4 ETO03272.1 - 0.0017 17.0 6.0 0.0022 16.7 4.2 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Cellulose_synt PF03552.9 ETO03272.1 - 0.017 13.4 0.2 0.024 12.9 0.1 1.2 1 0 0 1 1 1 0 Cellulose synthase Band_3_cyto PF07565.8 ETO03272.1 - 0.14 11.6 6.7 0.3 10.5 4.7 1.6 1 1 0 1 1 1 0 Band 3 cytoplasmic domain SR-25 PF10500.4 ETO03272.1 - 1.4 8.3 22.2 0.98 8.8 14.2 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ndc1_Nup PF09531.5 ETO03272.1 - 4.4 5.5 10.1 7.7 4.8 7.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pneumo_att_G PF05539.6 ETO03272.1 - 8.6 5.6 13.2 12 5.0 9.1 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G zf-C3HC4_2 PF13923.1 ETO03273.1 - 0.016 15.2 2.6 0.081 12.9 1.0 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Toxin_1 PF00087.16 ETO03273.1 - 0.16 12.3 4.7 0.81 10.1 0.6 2.3 2 0 0 2 2 2 0 Snake toxin AAA_5 PF07728.9 ETO03275.1 - 0.0053 16.4 0.0 0.34 10.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETO03275.1 - 0.014 15.5 0.0 0.028 14.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 ETO03275.1 - 0.017 15.3 0.0 0.021 15.0 0.0 1.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CobA_CobO_BtuR PF02572.10 ETO03275.1 - 0.021 14.4 0.0 0.022 14.4 0.0 1.1 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP zf-C3HC4_2 PF13923.1 ETO03277.1 - 0.00011 22.1 1.8 0.00047 20.1 1.2 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO03277.1 - 0.0012 18.6 3.9 0.0012 18.6 2.7 1.9 2 0 0 2 2 2 1 Ring finger domain DUF1644 PF07800.7 ETO03277.1 - 0.042 13.7 12.5 0.07 12.9 8.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) DUF4611 PF15387.1 ETO03277.1 - 0.066 13.3 1.1 0.2 11.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Herpes_UL95 PF03038.9 ETO03278.1 - 0.05 12.4 4.8 0.052 12.4 3.3 1.1 1 0 0 1 1 1 0 UL95 family Dimer_Tnp_hAT PF05699.9 ETO03278.1 - 1.1 8.9 4.5 0.79 9.3 0.2 2.4 1 1 0 2 2 2 0 hAT family C-terminal dimerisation region Presenilin PF01080.12 ETO03278.1 - 4.7 5.9 7.4 4.8 5.8 5.1 1.0 1 0 0 1 1 1 0 Presenilin BcrAD_BadFG PF01869.15 ETO03279.1 - 0.0054 16.0 0.0 0.0069 15.7 0.0 1.1 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family RNase_T PF00929.19 ETO03279.1 - 0.12 12.6 0.0 0.29 11.3 0.0 1.9 1 1 0 1 1 1 0 Exonuclease Vfa1 PF08432.5 ETO03280.1 - 6.9 6.6 16.2 7.3 6.5 11.2 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 WD40 PF00400.27 ETO03282.1 - 1.4e-05 24.7 1.1 0.00048 19.9 0.1 2.6 2 1 0 2 2 2 1 WD domain, G-beta repeat HAD PF12710.2 ETO03282.1 - 0.046 13.8 0.0 0.046 13.8 0.0 1.0 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase SprB PF13573.1 ETO03282.1 - 0.1 12.2 2.8 4.3 7.0 0.0 2.2 2 0 0 2 2 2 0 SprB repeat RVT_1 PF00078.22 ETO03284.1 - 0.00013 21.4 0.3 0.00024 20.5 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_60s PF00428.14 ETO03285.1 - 0.044 14.1 1.6 0.064 13.6 1.1 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF1673 PF07895.6 ETO03286.1 - 0.004 16.6 7.2 0.004 16.6 5.0 2.2 1 1 0 2 2 2 1 Protein of unknown function (DUF1673) DUF4131 PF13567.1 ETO03286.1 - 0.012 14.9 0.0 0.044 13.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) HALZ PF02183.13 ETO03286.1 - 0.046 13.4 0.9 0.096 12.4 0.6 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF843 PF05814.6 ETO03286.1 - 0.16 11.7 3.4 0.57 10.0 2.5 1.9 1 1 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) Tau95 PF09734.4 ETO03287.1 - 0.0066 15.8 0.1 0.0066 15.8 0.1 1.5 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit EI24 PF07264.6 ETO03287.1 - 0.0097 15.3 0.1 0.014 14.8 0.1 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF2762 PF10960.3 ETO03287.1 - 0.013 15.2 0.3 0.038 13.7 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) IL34 PF15036.1 ETO03287.1 - 0.023 14.2 0.3 0.039 13.5 0.1 1.4 1 1 0 1 1 1 0 Interleukin 34 Mitofilin PF09731.4 ETO03287.1 - 0.12 11.0 8.7 0.15 10.6 6.0 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF4061 PF13270.1 ETO03287.1 - 0.13 12.3 2.2 0.25 11.4 1.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) DUF2666 PF10869.3 ETO03287.1 - 1.4 8.9 8.8 0.36 10.8 3.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) WD40 PF00400.27 ETO03289.1 - 3.1e-08 33.2 0.9 4.1e-08 32.7 0.2 1.6 2 0 0 2 2 2 1 WD domain, G-beta repeat ENTH PF01417.15 ETO03289.1 - 0.0022 17.8 0.8 0.025 14.4 0.4 2.2 1 1 1 2 2 2 1 ENTH domain DUF2666 PF10869.3 ETO03290.1 - 0.076 13.0 0.3 0.11 12.5 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2666) WD40 PF00400.27 ETO03291.1 - 1.1e-19 69.5 2.4 8.9e-11 41.2 0.0 3.0 3 0 0 3 3 3 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO03291.1 - 0.0031 16.3 3.7 0.68 8.6 0.6 2.8 1 1 1 2 2 2 2 Nup133 N terminal like Nup160 PF11715.3 ETO03291.1 - 0.016 13.3 0.2 0.016 13.3 0.1 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DUF2700 PF10912.3 ETO03293.1 - 0.025 14.5 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2700) UME PF08064.8 ETO03294.1 - 0.029 14.3 0.2 0.047 13.6 0.1 1.3 1 0 0 1 1 1 0 UME (NUC010) domain DUF3492 PF11997.3 ETO03294.1 - 0.11 12.0 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) STAT_alpha PF01017.15 ETO03295.1 - 0.027 14.1 11.8 0.029 14.0 8.2 1.1 1 0 0 1 1 1 0 STAT protein, all-alpha domain DUF4200 PF13863.1 ETO03295.1 - 0.37 10.7 23.6 0.5 10.3 16.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Colicin-DNase PF12639.2 ETO03295.1 - 0.6 10.3 7.4 1.1 9.5 5.1 1.6 1 1 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin CBFB_NFYA PF02045.10 ETO03295.1 - 0.7 10.4 7.1 0.15 12.6 2.6 1.6 2 0 0 2 2 2 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Transposase_22 PF02994.9 ETO03295.1 - 0.87 8.0 15.8 0.93 7.9 10.9 1.0 1 0 0 1 1 1 0 L1 transposable element DivIVA PF05103.8 ETO03295.1 - 1.8 8.6 16.6 2.5 8.1 11.5 1.2 1 0 0 1 1 1 0 DivIVA protein Jnk-SapK_ap_N PF09744.4 ETO03295.1 - 5.1 7.0 16.6 5.3 7.0 11.5 1.0 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 ASL_C PF08328.6 ETO03296.1 - 0.083 12.7 0.9 0.33 10.8 0.2 2.2 2 1 0 2 2 2 0 Adenylosuccinate lyase C-terminal DUF3510 PF12022.3 ETO03296.1 - 4 7.5 12.5 0.38 10.8 0.2 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF3510) TPR_MLP1_2 PF07926.7 ETO03297.1 - 0.00082 19.1 5.3 0.086 12.5 0.7 2.1 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein EzrA PF06160.7 ETO03297.1 - 0.012 13.7 1.8 0.02 13.0 1.3 1.4 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF4200 PF13863.1 ETO03297.1 - 0.013 15.4 8.5 0.31 10.9 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) DUF812 PF05667.6 ETO03297.1 - 0.021 13.3 5.0 0.023 13.2 2.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF812) GrpE PF01025.14 ETO03297.1 - 0.029 13.9 1.6 0.039 13.5 1.1 1.2 1 0 0 1 1 1 0 GrpE DUF4201 PF13870.1 ETO03297.1 - 0.038 13.4 3.4 0.079 12.3 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Med4 PF10018.4 ETO03297.1 - 0.048 13.0 0.3 0.062 12.7 0.2 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Spc7 PF08317.6 ETO03297.1 - 0.081 11.5 4.9 0.031 12.9 1.7 1.4 2 0 0 2 2 2 0 Spc7 kinetochore protein Snapin_Pallidin PF14712.1 ETO03297.1 - 0.082 13.2 3.3 0.14 12.4 0.6 2.1 2 0 0 2 2 2 0 Snapin/Pallidin ParB PF08775.5 ETO03297.1 - 0.11 12.8 4.1 0.079 13.2 1.6 1.6 2 0 0 2 2 2 0 ParB family Cep57_MT_bd PF06657.8 ETO03297.1 - 0.12 12.3 3.2 0.24 11.3 1.7 1.8 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF643 PF04867.7 ETO03297.1 - 0.17 12.2 2.6 0.41 11.0 0.4 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF643) DivIC PF04977.10 ETO03297.1 - 0.17 11.3 2.4 0.38 10.2 1.7 1.6 1 0 0 1 1 1 0 Septum formation initiator Seryl_tRNA_N PF02403.17 ETO03297.1 - 0.19 11.7 6.1 0.086 12.8 2.4 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Filament PF00038.16 ETO03297.1 - 0.21 11.0 6.4 0.26 10.7 1.4 1.9 1 1 0 2 2 2 0 Intermediate filament protein TPD52 PF04201.10 ETO03297.1 - 0.29 10.8 3.3 0.43 10.2 2.1 1.4 1 1 0 1 1 1 0 Tumour protein D52 family DUF972 PF06156.8 ETO03297.1 - 0.3 11.4 5.3 0.71 10.2 3.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) CENP-H PF05837.7 ETO03297.1 - 0.62 10.2 5.5 0.53 10.4 1.9 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Siah-Interact_N PF09032.6 ETO03297.1 - 0.68 10.0 5.1 4.2 7.4 1.4 2.4 2 0 0 2 2 2 0 Siah interacting protein, N terminal Myosin_tail_1 PF01576.14 ETO03297.1 - 0.79 7.3 7.3 0.19 9.3 2.7 1.5 2 0 0 2 2 2 0 Myosin tail ETRAMP PF09716.5 ETO03297.1 - 1.2 9.1 3.7 11 6.0 1.9 2.3 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) WD40 PF00400.27 ETO03298.1 - 3.6e-19 67.8 9.0 6e-11 41.7 1.7 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO03298.1 - 0.00014 20.1 0.9 0.00021 19.6 0.2 1.5 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Arena_nucleocap PF00843.12 ETO03298.1 - 0.11 10.3 2.0 3.5 5.4 0.0 2.1 2 0 0 2 2 2 0 Arenavirus nucleocapsid protein OmpH PF03938.9 ETO03298.1 - 5.6 6.8 13.2 7.5 6.4 9.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Gly-zipper_Omp PF13488.1 ETO03299.1 - 0.00011 21.7 1.9 0.013 15.1 1.3 2.8 1 1 0 1 1 1 1 Glycine zipper Gly-zipper_YMGG PF13441.1 ETO03299.1 - 0.011 15.2 0.2 0.31 10.5 0.1 2.7 1 1 0 1 1 1 0 YMGG-like Gly-zipper Bacteriocin_IIc PF10439.4 ETO03299.1 - 8.2 6.6 19.3 4e+03 -2.0 13.4 3.0 1 1 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide RTC PF01137.16 ETO03300.1 - 1.6e-39 135.0 0.0 2e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase V-SNARE_C PF12352.3 ETO03301.1 - 2.7e-05 24.1 4.4 2.7e-05 24.1 3.1 2.0 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 ETO03301.1 - 0.0004 20.0 0.3 0.0004 20.0 0.2 2.6 2 1 1 3 3 3 1 Sec20 V-SNARE PF05008.10 ETO03301.1 - 0.023 14.8 2.3 0.076 13.1 1.6 2.0 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus DUF2321 PF10083.4 ETO03301.1 - 0.035 13.5 1.2 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Arch_ATPase PF01637.13 ETO03301.1 - 0.095 12.3 1.6 0.26 10.9 1.1 1.7 1 1 0 1 1 1 0 Archaeal ATPase Syntaxin-6_N PF09177.6 ETO03301.1 - 0.11 12.9 9.6 2.4 8.6 0.7 2.6 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Mnd1 PF03962.10 ETO03301.1 - 0.14 11.8 7.1 0.043 13.4 1.9 2.1 1 1 2 3 3 3 0 Mnd1 family TcdB_N PF12918.2 ETO03301.1 - 0.27 11.3 5.1 0.33 11.0 2.0 2.2 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain DivIC PF04977.10 ETO03301.1 - 0.37 10.3 7.4 1.3 8.5 0.3 3.3 2 1 1 3 3 3 0 Septum formation initiator Hom_end_hint PF05203.11 ETO03302.1 - 0.15 11.7 0.2 0.43 10.2 0.1 1.7 1 1 1 2 2 2 0 Hom_end-associated Hint tRNA-synt_2c PF01411.14 ETO03304.1 - 2.9e-05 22.5 0.2 2.9e-05 22.5 0.1 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 ETO03304.1 - 3.6e-05 23.5 0.7 9.5e-05 22.2 0.1 2.0 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain WD40 PF00400.27 ETO03305.1 - 7.2e-58 190.5 21.9 4.3e-12 45.4 0.3 7.4 8 0 0 8 8 8 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO03305.1 - 1.5e-10 39.8 0.7 0.0088 14.2 0.0 4.7 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO03305.1 - 0.001 17.9 2.3 1.9 7.1 0.0 3.8 1 1 1 3 3 3 2 Nup133 N terminal like HAD PF12710.2 ETO03305.1 - 0.068 13.3 2.4 2.6 8.1 1.7 2.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase TRP PF06011.7 ETO03308.1 - 0.026 13.0 0.0 0.026 13.0 0.0 1.0 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Nop52 PF05997.7 ETO03309.1 - 7e-26 90.9 5.2 5e-25 88.2 3.6 2.0 1 1 0 1 1 1 1 Nucleolar protein,Nop52 zf-TFIIIC PF12660.2 ETO03309.1 - 0.16 11.8 0.6 11 5.9 0.0 2.2 1 1 1 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex NACHT PF05729.7 ETO03310.1 - 3.6e-10 39.7 0.0 6.6e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETO03310.1 - 2.3e-05 24.5 0.0 0.0001 22.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETO03310.1 - 0.00016 21.9 0.1 0.00016 21.9 0.0 3.7 3 1 1 4 4 4 1 AAA domain AAA_33 PF13671.1 ETO03310.1 - 0.0087 15.9 0.0 0.07 13.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 ETO03310.1 - 0.01 14.9 0.0 0.04 12.9 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin UPF0079 PF02367.12 ETO03310.1 - 0.012 15.2 0.0 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 ETO03310.1 - 0.012 16.3 0.0 0.012 16.3 0.0 3.0 3 2 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 ETO03310.1 - 0.013 15.6 2.3 0.059 13.5 0.3 3.0 2 1 0 2 2 2 0 RNA helicase AAA PF00004.24 ETO03310.1 - 0.018 15.2 0.0 0.055 13.6 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP_bind_2 PF03668.10 ETO03310.1 - 0.092 11.8 0.6 0.3 10.1 0.0 2.1 3 0 0 3 3 3 0 P-loop ATPase protein family AAA_16 PF13191.1 ETO03310.1 - 0.18 11.7 0.2 1.3 8.9 0.0 2.3 2 1 1 3 3 3 0 AAA ATPase domain HEAT PF02985.17 ETO03311.1 - 0.00084 19.2 0.1 0.59 10.3 0.0 3.3 4 0 0 4 4 4 1 HEAT repeat Proteasom_PSMB PF10508.4 ETO03311.1 - 0.038 12.2 0.1 0.043 12.0 0.0 1.2 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit HEAT_2 PF13646.1 ETO03311.1 - 0.047 13.9 0.0 1.3 9.3 0.0 2.3 1 1 0 1 1 1 0 HEAT repeats Kelch_1 PF01344.20 ETO03313.1 - 7.7e-09 34.9 0.4 0.00071 19.0 0.1 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.10 ETO03313.1 - 1.2e-06 28.0 0.1 0.0084 15.8 0.1 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 ETO03313.1 - 2.7e-06 27.0 0.1 0.008 15.9 0.0 2.4 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO03313.1 - 3.5e-06 26.9 1.0 0.0062 16.6 0.2 2.5 1 1 1 2 2 2 2 Kelch motif Kelch_5 PF13854.1 ETO03313.1 - 3.6e-05 23.6 0.7 0.066 13.1 0.2 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 ETO03313.1 - 0.0012 18.9 0.1 0.057 13.5 0.0 2.7 3 0 0 3 3 3 1 Galactose oxidase, central domain WD40 PF00400.27 ETO03314.1 - 0.0021 17.8 1.4 0.16 11.8 0.1 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat CRT-like PF08627.5 ETO03314.1 - 0.047 13.6 3.3 0.064 13.1 2.3 1.2 1 0 0 1 1 1 0 CRT-like PLA2_B PF01735.13 ETO03315.1 - 0.093 10.8 0.8 0.11 10.6 0.6 1.0 1 0 0 1 1 1 0 Lysophospholipase catalytic domain Phi_1 PF04674.7 ETO03315.1 - 0.32 10.1 2.6 0.35 9.9 1.8 1.0 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region DUF4302 PF14135.1 ETO03315.1 - 0.33 10.2 5.8 0.34 10.2 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4302) RHD PF00554.17 ETO03315.1 - 0.33 10.6 8.4 0.4 10.3 5.8 1.2 1 0 0 1 1 1 0 Rel homology domain (RHD) HemX PF04375.9 ETO03315.1 - 0.44 9.0 5.1 0.53 8.8 3.5 1.0 1 0 0 1 1 1 0 HemX DDHD PF02862.12 ETO03315.1 - 0.65 9.7 6.2 0.73 9.5 4.3 1.1 1 0 0 1 1 1 0 DDHD domain Mgr1 PF08602.5 ETO03315.1 - 0.8 8.6 7.7 0.81 8.6 5.4 1.0 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit Atg14 PF10186.4 ETO03315.1 - 1.2 8.0 13.0 1.1 8.0 9.0 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4557 PF15101.1 ETO03315.1 - 1.9 8.2 8.6 2.3 8.0 6.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) RNA_pol_Rpb1_2 PF00623.15 ETO03315.1 - 2.8 7.8 7.0 3.1 7.7 4.8 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 2 DUF4220 PF13968.1 ETO03315.1 - 3.4 6.6 6.4 3.5 6.6 4.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DUF2203 PF09969.4 ETO03315.1 - 3.6 7.8 8.1 4.2 7.6 5.6 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF2956 PF11169.3 ETO03315.1 - 3.9 7.4 20.0 5.8 6.9 13.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) YebO PF13974.1 ETO03315.1 - 4.5 7.1 8.1 6.3 6.6 5.6 1.3 1 0 0 1 1 1 0 YebO-like protein GAGA_bind PF06217.7 ETO03315.1 - 6.1 6.7 15.2 6.4 6.6 10.5 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family SecA_DEAD PF07517.9 ETO03315.1 - 8.4 5.5 7.8 9.3 5.4 5.4 1.1 1 0 0 1 1 1 0 SecA DEAD-like domain FemAB PF02388.11 ETO03315.1 - 9.1 4.8 14.0 9.9 4.7 9.7 1.0 1 0 0 1 1 1 0 FemAB family DUF1764 PF08576.5 ETO03315.1 - 9.2 7.1 16.4 11 6.8 11.4 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) WD40 PF00400.27 ETO03316.1 - 1.1e-30 104.3 12.7 1.1e-09 37.8 0.3 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO03316.1 - 4.4e-06 25.1 4.7 0.015 13.4 0.0 3.2 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO03316.1 - 0.0039 15.9 5.5 0.89 8.2 0.0 3.3 1 1 1 3 3 3 2 Nup133 N terminal like WD40 PF00400.27 ETO03317.1 - 2.1e-22 78.1 12.0 8e-11 41.3 0.9 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO03317.1 - 0.00012 20.3 2.3 0.01 14.0 0.3 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 RED_C PF07807.6 ETO03317.1 - 0.15 12.2 0.4 1.8 8.7 0.0 2.0 1 1 0 2 2 2 0 RED-like protein C-terminal region DUF1474 PF07342.6 ETO03318.1 - 0.059 13.5 1.0 0.089 13.0 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1474) DBD_Tnp_Hermes PF10683.4 ETO03318.1 - 0.14 11.6 0.1 1.2 8.6 0.0 2.3 3 0 0 3 3 3 0 Hermes transposase DNA-binding domain ALMT PF11744.3 ETO03319.1 - 0.032 12.8 5.0 0.036 12.7 3.5 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter RP-C_C PF11800.3 ETO03319.1 - 0.061 13.0 9.8 0.074 12.7 6.8 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF3450 PF11932.3 ETO03319.1 - 0.16 11.2 10.6 0.1 11.8 6.6 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Baculo_PEP_C PF04513.7 ETO03319.1 - 0.16 11.8 2.6 0.22 11.3 1.8 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2347 PF09804.4 ETO03319.1 - 0.24 10.6 5.9 0.28 10.4 4.1 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) NOA36 PF06524.7 ETO03319.1 - 0.4 9.9 9.0 0.46 9.6 6.2 1.1 1 0 0 1 1 1 0 NOA36 protein DUF809 PF05663.6 ETO03319.1 - 0.45 10.4 8.3 0.53 10.2 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF809) L31 PF09784.4 ETO03319.1 - 0.59 10.2 4.7 0.67 10.0 2.7 1.4 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L31 Paf1 PF03985.8 ETO03319.1 - 0.83 8.3 17.2 0.93 8.1 11.9 1.1 1 0 0 1 1 1 0 Paf1 Z1 PF10593.4 ETO03319.1 - 0.96 8.6 5.9 1.2 8.2 4.1 1.3 1 0 0 1 1 1 0 Z1 domain SecD-TM1 PF13721.1 ETO03319.1 - 0.97 9.7 3.2 1.3 9.2 2.2 1.3 1 0 0 1 1 1 0 SecD export protein N-terminal TM region DUF2457 PF10446.4 ETO03319.1 - 1.5 7.4 21.2 1.6 7.3 14.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RNA_pol_3_Rpc31 PF11705.3 ETO03319.1 - 1.5 8.6 23.7 1.8 8.4 16.4 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Mt_ATP-synt_D PF05873.7 ETO03319.1 - 2 8.0 11.1 2.4 7.8 7.7 1.2 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) RXT2_N PF08595.6 ETO03319.1 - 2.1 8.1 11.0 3.1 7.6 7.6 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal RRM_3 PF08777.6 ETO03319.1 - 2.9 7.7 12.3 3.6 7.4 8.6 1.1 1 0 0 1 1 1 0 RNA binding motif V_ATPase_I PF01496.14 ETO03319.1 - 3.3 5.4 14.4 3.2 5.5 10.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DDHD PF02862.12 ETO03319.1 - 3.3 7.4 6.7 3.5 7.3 4.7 1.1 1 0 0 1 1 1 0 DDHD domain SEO_N PF14576.1 ETO03319.1 - 5.6 6.1 9.6 1.1 8.5 0.8 2.1 1 1 1 2 2 2 0 Sieve element occlusion N-terminus Spc24 PF08286.6 ETO03319.1 - 6.5 6.4 21.2 1.4 8.6 12.1 1.7 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 BTV_NS2 PF04514.7 ETO03319.1 - 6.7 5.4 15.3 7.5 5.3 10.6 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Cytomega_UL84 PF06284.6 ETO03319.1 - 6.9 4.9 6.7 6 5.1 4.6 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein FemAB PF02388.11 ETO03319.1 - 8.1 5.0 14.6 9.2 4.8 10.1 1.1 1 0 0 1 1 1 0 FemAB family Hox9_act PF04617.8 ETO03319.1 - 9.1 6.4 7.0 11 6.1 4.9 1.1 1 0 0 1 1 1 0 Hox9 activation region GPDPase_memb PF10110.4 ETO03320.1 - 0.38 10.1 4.2 0.21 10.9 0.9 1.9 1 1 1 2 2 2 0 Membrane domain of glycerophosphoryl diester phosphodiesterase WD40 PF00400.27 ETO03321.1 - 7.4e-69 225.3 21.3 8e-14 50.8 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO03321.1 - 7.1e-07 27.7 5.8 0.00011 20.4 1.1 3.7 1 1 1 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO03321.1 - 1.2e-05 24.8 0.1 8.1e-05 22.1 0.0 2.2 1 1 0 1 1 1 1 PQQ-like domain PD40 PF07676.7 ETO03321.1 - 4.9e-05 22.8 4.1 6.1 6.6 0.0 6.1 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO03321.1 - 0.00011 20.6 0.5 0.12 10.6 0.0 3.2 1 1 2 4 4 4 3 Cytochrome D1 heme domain SGL PF08450.7 ETO03321.1 - 0.0013 18.2 0.2 0.012 14.9 0.1 2.2 1 1 1 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Resistin PF06954.6 ETO03321.1 - 0.0039 17.4 6.0 10 6.5 0.1 5.1 2 2 4 6 6 6 1 Resistin DUF1258 PF06869.7 ETO03321.1 - 0.038 13.0 3.5 0.44 9.5 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1258) F420_ligase PF01996.11 ETO03321.1 - 0.058 12.4 0.0 0.12 11.4 0.0 1.6 1 1 0 1 1 1 0 F420-0:Gamma-glutamyl ligase CDRT4 PF15213.1 ETO03321.1 - 0.16 12.0 0.1 0.69 10.0 0.0 2.0 2 0 0 2 2 2 0 CMT1A duplicated region transcript 4 protein WD40 PF00400.27 ETO03322.1 - 8.8e-43 142.7 20.8 2.5e-13 49.3 0.4 6.8 6 1 1 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO03322.1 - 1.2e-07 31.5 0.6 0.0034 17.1 0.1 2.9 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO03322.1 - 3e-05 23.5 2.4 3.5 7.4 0.0 4.9 6 0 0 6 6 6 3 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO03322.1 - 0.0001 21.8 0.2 0.0014 18.1 0.1 2.4 1 1 0 1 1 1 1 PQQ-like domain Coatomer_WDAD PF04053.9 ETO03322.1 - 0.0058 15.4 2.4 1.4 7.6 0.2 2.4 1 1 1 2 2 2 2 Coatomer WD associated region F420_ligase PF01996.11 ETO03322.1 - 0.04 12.9 0.0 0.052 12.6 0.0 1.3 1 1 0 1 1 1 0 F420-0:Gamma-glutamyl ligase Resistin PF06954.6 ETO03322.1 - 0.081 13.2 1.1 12 6.2 0.0 3.7 2 2 2 4 4 4 0 Resistin DUF3439 PF11921.3 ETO03323.1 - 0.00028 20.6 5.7 0.00042 20.0 4.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) MIP-T3 PF10243.4 ETO03323.1 - 0.17 10.2 27.1 0.19 10.1 18.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Mucin PF01456.12 ETO03323.1 - 0.22 11.3 9.7 0.32 10.7 6.7 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF966 PF06136.8 ETO03323.1 - 1.4 8.2 13.5 1.5 8.1 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Vitellogenin_N PF01347.17 ETO03323.1 - 2.4 6.2 14.4 3.2 5.8 10.0 1.1 1 0 0 1 1 1 0 Lipoprotein amino terminal region DUF3435 PF11917.3 ETO03323.1 - 2.9 6.4 16.5 3.6 6.2 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Neur_chan_memb PF02932.11 ETO03323.1 - 7.8 6.3 7.9 8.7 6.1 5.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ribosomal_S19 PF00203.16 ETO03324.1 - 4.3e-26 90.3 0.7 9e-26 89.3 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S19 FemAB PF02388.11 ETO03324.1 - 0.43 9.1 4.2 0.57 8.8 2.9 1.1 1 0 0 1 1 1 0 FemAB family 2OG-FeII_Oxy_3 PF13640.1 ETO03325.1 - 0.00099 19.5 0.0 0.0082 16.6 0.0 2.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 ETO03325.1 - 0.026 14.8 0.0 0.62 10.3 0.0 2.5 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily ETRAMP PF09716.5 ETO03326.1 - 0.096 12.6 7.6 0.46 10.4 3.4 2.9 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Rot1 PF10681.4 ETO03326.1 - 2 7.7 5.3 3.2 7.0 3.7 1.3 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal YqfQ PF14181.1 ETO03326.1 - 3.3 7.7 11.1 6.1 6.8 7.7 1.4 1 0 0 1 1 1 0 YqfQ-like protein SR-25 PF10500.4 ETO03326.1 - 6.7 6.1 20.5 12 5.3 14.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-RanBP PF00641.13 ETO03328.1 - 2.1e-05 23.5 5.6 4.1e-05 22.5 3.9 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Microtub_assoc PF07989.6 ETO03329.1 - 0.065 13.0 0.7 0.083 12.7 0.5 1.4 1 0 0 1 1 1 0 Microtubule associated GTP_EFTU_D3 PF03143.12 ETO03332.1 - 3.6e-06 27.0 0.1 9.7e-06 25.6 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D4 PF14578.1 ETO03332.1 - 0.00035 20.1 0.0 0.0006 19.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.20 ETO03332.1 - 0.0041 17.2 0.0 0.0089 16.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 VID27 PF08553.5 ETO03333.1 - 0.0043 15.3 15.8 0.0053 15.0 11.0 1.2 1 0 0 1 1 1 1 VID27 cytoplasmic protein MIP-T3 PF10243.4 ETO03333.1 - 0.0071 14.8 20.2 0.0086 14.5 14.0 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Daxx PF03344.10 ETO03333.1 - 0.0079 14.7 32.6 0.0097 14.4 22.6 1.1 1 0 0 1 1 1 1 Daxx Family RRN3 PF05327.6 ETO03333.1 - 0.067 11.3 10.8 0.098 10.7 7.5 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 U79_P34 PF03064.11 ETO03333.1 - 0.09 12.2 15.6 0.11 12.0 10.8 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Nop14 PF04147.7 ETO03333.1 - 0.19 9.6 38.8 0.23 9.3 26.9 1.1 1 0 0 1 1 1 0 Nop14-like family Apt1 PF10351.4 ETO03333.1 - 0.53 9.0 12.3 0.74 8.5 8.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Saw1 PF11561.3 ETO03333.1 - 1.1 8.5 10.0 1.9 7.8 6.9 1.3 1 0 0 1 1 1 0 Single strand annealing-weakened 1 CDC27 PF09507.5 ETO03333.1 - 1.5 7.9 23.5 2 7.5 16.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Band_3_cyto PF07565.8 ETO03333.1 - 3.3 7.1 6.3 4.6 6.6 4.4 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Attractin PF08037.6 ETO03334.1 - 0.063 13.0 0.4 0.091 12.5 0.2 1.3 1 0 0 1 1 1 0 Attractin family DUF4209 PF13910.1 ETO03335.1 - 0.033 14.2 0.1 0.077 13.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4209) SAC3_GANP PF03399.11 ETO03335.1 - 0.034 13.6 0.7 0.052 13.1 0.5 1.5 1 1 0 1 1 1 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family AbiH PF14253.1 ETO03339.1 - 0.0019 17.8 4.7 0.0023 17.5 3.3 1.2 1 0 0 1 1 1 1 Bacteriophage abortive infection AbiH FlaC_arch PF05377.6 ETO03339.1 - 0.1 12.4 4.6 0.71 9.8 0.1 2.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Vac_Fusion PF02346.11 ETO03339.1 - 0.32 10.4 2.3 0.91 8.9 0.8 2.4 2 1 0 2 2 2 0 Chordopoxvirus fusion protein DUF972 PF06156.8 ETO03339.1 - 0.79 10.0 4.4 1.6 9.1 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) HSCB_C PF07743.8 ETO03339.1 - 0.79 10.2 5.0 2.4 8.6 0.9 2.6 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain WBP-1 PF11669.3 ETO03340.1 - 0.0011 18.9 1.6 0.0016 18.4 1.1 1.3 1 0 0 1 1 1 1 WW domain-binding protein 1 Vps51 PF08700.6 ETO03342.1 - 0.35 10.7 6.0 4.4 7.2 0.3 3.6 1 1 2 3 3 2 0 Vps51/Vps67 DUF885 PF05960.6 ETO03342.1 - 2 7.4 10.4 7.9 5.5 5.5 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF885) Phasin PF05597.6 ETO03342.1 - 5.4 6.7 14.1 0.21 11.3 1.5 3.5 4 0 0 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DNA_ligase_aden PF01653.13 ETO03343.1 - 0.049 12.5 0.1 0.062 12.2 0.1 1.1 1 0 0 1 1 1 0 NAD-dependent DNA ligase adenylation domain Translat_reg PF01818.12 ETO03343.1 - 0.06 12.8 1.9 0.069 12.6 1.3 1.1 1 0 0 1 1 1 0 Bacteriophage translational regulator DEP PF00610.16 ETO03345.1 - 0.079 12.7 0.6 3.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) GTP_EFTU PF00009.22 ETO03346.1 - 2.3e-20 72.8 0.0 2.7e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 ETO03346.1 - 0.0031 17.8 0.4 0.0034 17.6 0.3 1.4 1 1 0 1 1 1 1 AAA domain Arf PF00025.16 ETO03346.1 - 0.014 14.6 0.2 0.08 12.1 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_17 PF13207.1 ETO03346.1 - 0.044 14.6 0.2 0.067 14.0 0.2 1.6 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 ETO03346.1 - 0.052 14.0 0.1 0.14 12.6 0.1 1.7 1 1 0 1 1 1 0 Miro-like protein NIR_SIR_ferr PF03460.12 ETO03346.1 - 0.058 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Nitrite/Sulfite reductase ferredoxin-like half domain MMR_HSR1 PF01926.18 ETO03346.1 - 0.11 12.4 0.5 0.38 10.7 0.4 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AnfO_nitrog PF09582.5 ETO03347.1 - 0.028 13.5 0.6 9.5 5.2 0.0 2.8 3 0 0 3 3 3 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) DUF3596 PF12167.3 ETO03349.1 - 0.26 10.8 1.4 0.72 9.4 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3596) Kelch_1 PF01344.20 ETO03350.1 - 2.6e-06 26.8 0.3 7.1e-05 22.2 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO03350.1 - 7.1e-06 25.5 0.3 0.00043 19.9 0.1 3.2 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 ETO03350.1 - 3.1e-05 23.9 0.5 0.055 13.6 0.1 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETO03350.1 - 0.00024 20.8 0.1 0.12 12.1 0.0 3.7 2 1 1 3 3 3 1 Galactose oxidase, central domain DUF4393 PF14337.1 ETO03352.1 - 0.0083 15.5 0.3 0.013 14.9 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4393) Ashwin PF15323.1 ETO03352.1 - 0.056 13.4 3.6 0.071 13.1 2.5 1.1 1 0 0 1 1 1 0 Developmental protein EST1 PF10374.4 ETO03352.1 - 0.06 13.3 0.8 1.1 9.2 0.2 2.7 1 1 1 2 2 2 0 Telomerase activating protein Est1 PP1_inhibitor PF05361.7 ETO03352.1 - 0.086 12.5 0.4 0.3 10.7 0.0 1.9 2 0 0 2 2 2 0 PKC-activated protein phosphatase-1 inhibitor PPC PF04151.10 ETO03352.1 - 0.86 10.6 6.2 1.3 10.0 4.3 1.3 1 0 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain Secretin_N_2 PF07655.8 ETO03352.1 - 2 8.8 12.9 4.7 7.6 8.8 1.8 1 1 1 2 2 2 0 Secretin N-terminal domain DUF896 PF05979.7 ETO03353.1 - 0.007 15.9 0.5 0.016 14.7 0.3 1.6 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF896) Peptidase_C80 PF11713.3 ETO03353.1 - 0.049 13.4 2.0 0.064 13.0 1.4 1.1 1 0 0 1 1 1 0 Peptidase C80 family Fanconi_A PF03511.9 ETO03354.1 - 0.026 14.2 0.1 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 Fanconi anaemia group A protein PyrI_C PF02748.10 ETO03354.1 - 0.42 10.0 5.0 0.66 9.4 1.3 2.2 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Tubulin PF00091.20 ETO03355.1 - 3.2e-26 92.5 0.1 5.8e-26 91.6 0.1 1.4 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.1 ETO03355.1 - 0.015 14.2 0.1 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 Tubulin like NAD_binding_6 PF08030.7 ETO03357.1 - 8.6e-12 45.2 0.0 1.6e-11 44.3 0.0 1.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain RNase_H PF00075.19 ETO03358.1 - 7.3e-11 42.5 0.0 1.1e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 RNase H CTK3 PF12243.3 ETO03358.1 - 0.016 14.8 0.4 1.7 8.2 0.0 2.7 2 1 1 3 3 3 0 CTD kinase subunit gamma CTK3 zf-RVT PF13966.1 ETO03358.1 - 0.042 14.1 0.4 0.082 13.2 0.2 1.5 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Lipase_GDSL_3 PF14606.1 ETO03358.1 - 0.094 12.4 0.1 0.23 11.1 0.0 1.6 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Chal_sti_synt_C PF02797.10 ETO03358.1 - 0.097 12.5 0.0 0.18 11.6 0.0 1.5 1 1 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain PRD PF00874.15 ETO03358.1 - 0.16 12.0 2.8 0.56 10.3 0.4 2.3 2 0 0 2 2 2 0 PRD domain tRNA_Me_trans PF03054.11 ETO03359.1 - 5.9e-23 80.9 0.0 6.7e-23 80.8 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase tRNA_Me_trans PF03054.11 ETO03360.1 - 1.5e-43 148.7 0.0 1.8e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.12 ETO03360.1 - 0.0033 16.3 0.0 0.0063 15.4 0.0 1.4 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 ETO03360.1 - 0.041 13.3 0.0 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase Ras PF00071.17 ETO03361.1 - 2.7e-33 114.6 2.2 3.2e-33 114.4 1.5 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO03361.1 - 5.4e-07 30.1 0.4 8.4e-07 29.5 0.1 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO03361.1 - 1.6e-06 27.4 0.5 2.1e-06 27.1 0.3 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO03361.1 - 0.0042 16.5 0.8 0.0079 15.6 0.6 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FAD-SLDH PF12318.3 ETO03361.1 - 0.051 13.2 0.9 1.9 8.1 0.0 2.1 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase DUF4265 PF14085.1 ETO03361.1 - 0.057 13.1 0.0 0.096 12.4 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4265) FAD_binding_8 PF08022.7 ETO03362.1 - 0.083 12.7 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 FAD-binding domain DUF1117 PF06547.7 ETO03362.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) Stn1 PF10451.4 ETO03363.1 - 0.14 10.9 4.0 0.88 8.3 0.2 2.5 2 1 1 3 3 3 0 Telomere regulation protein Stn1 TPR_12 PF13424.1 ETO03364.1 - 8.9e-09 35.1 0.1 1.3e-06 28.2 0.0 2.3 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO03364.1 - 2.1e-07 30.1 3.4 0.00014 21.3 0.4 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO03364.1 - 4.7e-06 26.1 5.2 0.0012 18.4 0.1 3.2 2 1 1 3 3 3 2 TPR repeat TPR_7 PF13176.1 ETO03364.1 - 0.0075 15.9 0.0 0.063 13.0 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETO03364.1 - 0.013 15.4 0.0 0.16 11.9 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETO03364.1 - 0.015 15.2 2.3 1.4 9.0 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETO03364.1 - 0.052 13.1 4.2 0.083 12.5 0.4 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Fer4_12 PF13353.1 ETO03364.1 - 0.054 13.6 0.9 0.35 10.9 0.0 2.3 2 0 0 2 2 2 0 4Fe-4S single cluster domain TPR_17 PF13431.1 ETO03364.1 - 0.11 12.6 0.5 3.6 8.0 0.2 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat Lipase_GDSL_3 PF14606.1 ETO03364.1 - 0.12 12.1 2.1 0.4 10.3 0.4 2.1 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family InvH PF04741.7 ETO03365.1 - 0.079 12.8 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 InvH outer membrane lipoprotein DEAD PF00270.24 ETO03366.1 - 6.1e-18 64.8 0.1 5.7e-17 61.7 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 ETO03366.1 - 3.5e-05 23.7 0.8 0.00011 22.1 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 ETO03366.1 - 0.064 12.5 0.0 0.064 12.5 0.0 2.0 2 0 0 2 2 2 0 SecA DEAD-like domain PUB PF09409.5 ETO03367.1 - 0.017 14.8 1.7 0.056 13.2 1.2 2.0 1 1 0 1 1 1 0 PUB domain PYST-C1 PF09690.5 ETO03367.1 - 1.4 8.5 5.3 0.5 10.0 1.3 2.0 1 1 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) VIT1 PF01988.14 ETO03368.1 - 0.085 12.3 0.0 0.085 12.3 0.0 2.5 2 0 0 2 2 2 0 VIT family ABC_tran PF00005.22 ETO03369.1 - 4.8e-16 59.3 0.0 1.1e-15 58.0 0.0 1.6 2 0 0 2 2 2 1 ABC transporter ABC_ATPase PF09818.4 ETO03369.1 - 5e-06 25.3 0.1 6e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class SbcCD_C PF13558.1 ETO03369.1 - 5.3e-05 23.0 0.8 0.00098 19.0 0.5 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 ETO03369.1 - 7.8e-05 22.0 0.0 9.3e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETO03369.1 - 0.0002 21.4 0.0 0.00023 21.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain VCX_VCY PF15231.1 ETO03370.1 - 0.34 11.2 3.9 0.41 11.0 2.7 1.1 1 0 0 1 1 1 0 Variable charge X/Y family Chordopox_G3 PF06129.7 ETO03370.1 - 5.5 7.1 6.9 6.6 6.9 4.8 1.2 1 0 0 1 1 1 0 Chordopoxvirus G3 protein Peptidase_S49_N PF08496.5 ETO03371.1 - 0.35 10.6 3.3 0.51 10.1 2.3 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2570 PF10828.3 ETO03372.1 - 0.062 12.9 2.7 0.068 12.7 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DUF1528 PF07515.6 ETO03372.1 - 0.12 12.3 1.4 0.73 9.8 0.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1528) CRA PF06589.6 ETO03372.1 - 7.4 5.8 7.6 5 6.4 1.0 2.0 1 1 1 2 2 2 0 Circumsporozoite-related antigen (CRA) TPR_12 PF13424.1 ETO03373.1 - 3.4e-101 331.2 26.5 9.5e-25 86.3 0.6 4.3 1 1 4 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETO03373.1 - 6.9e-49 161.5 43.1 3.1e-10 39.2 1.1 7.0 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_10 PF13374.1 ETO03373.1 - 7.6e-49 162.3 0.0 1.1e-08 34.7 0.0 6.1 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_11 PF13414.1 ETO03373.1 - 1.4e-43 146.4 25.1 1.6e-15 56.4 2.1 4.4 3 2 0 4 4 4 4 TPR repeat TPR_2 PF07719.12 ETO03373.1 - 1.5e-43 143.1 26.5 3.2e-09 35.9 0.1 7.0 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETO03373.1 - 1.6e-35 118.1 47.6 3.9e-07 29.3 1.4 6.8 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.1 ETO03373.1 - 1.5e-32 108.8 7.3 9.8e-06 25.0 0.0 7.1 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 ETO03373.1 - 1.3e-24 86.2 0.7 4.9e-05 23.8 0.0 4.3 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_6 PF13174.1 ETO03373.1 - 8.4e-18 63.5 6.5 0.028 14.8 0.0 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETO03373.1 - 8.7e-18 62.9 29.2 0.00024 21.0 0.6 7.8 6 5 0 6 6 6 6 Tetratricopeptide repeat TPR_14 PF13428.1 ETO03373.1 - 1.4e-17 62.5 0.0 0.24 12.1 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO03373.1 - 2.8e-17 61.6 6.7 0.0024 17.0 0.0 6.2 6 0 0 6 6 6 5 SHNi-TPR SNAP PF14938.1 ETO03373.1 - 6e-13 48.5 5.8 2.1e-06 27.0 1.0 2.4 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP DUF627 PF04781.7 ETO03373.1 - 1.3e-12 47.3 6.5 0.27 10.8 0.1 6.0 2 1 4 6 6 6 4 Protein of unknown function (DUF627) DUF2225 PF09986.4 ETO03373.1 - 2.5e-07 30.3 10.2 0.023 14.1 0.2 3.5 1 1 3 4 4 4 4 Uncharacterized protein conserved in bacteria (DUF2225) Apc3 PF12895.2 ETO03373.1 - 2.6e-07 30.6 16.9 0.027 14.6 0.4 4.7 1 1 4 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 ETO03373.1 - 3.5e-07 29.9 20.8 0.038 13.8 0.5 6.3 5 1 2 7 7 7 3 MIT (microtubule interacting and transport) domain TPR_19 PF14559.1 ETO03373.1 - 3.7e-06 27.1 2.5 0.26 11.6 0.1 3.9 1 1 4 5 5 5 2 Tetratricopeptide repeat DUF3856 PF12968.2 ETO03373.1 - 6e-06 26.1 2.4 1.5 8.6 0.1 4.0 1 1 2 4 4 4 2 Domain of Unknown Function (DUF3856) UVR PF02151.14 ETO03373.1 - 0.00011 21.6 15.0 3.1 7.4 0.2 5.9 6 0 0 6 6 6 2 UvrB/uvrC motif DUF1120 PF06551.7 ETO03373.1 - 0.00026 21.2 0.2 21 5.4 0.0 4.4 1 1 4 5 5 5 0 Protein of unknown function (DUF1120) ATP-synt_D PF01813.12 ETO03373.1 - 0.0014 18.1 0.3 24 4.4 0.0 4.4 1 1 4 5 5 5 0 ATP synthase subunit D KCNQC3-Ank-G_bd PF11956.3 ETO03373.1 - 0.0028 17.6 0.2 6 6.9 0.0 4.1 1 1 4 5 5 5 0 Ankyrin-G binding motif of KCNQ2-3 mit_SMPDase PF14724.1 ETO03373.1 - 0.0046 14.8 2.0 0.74 7.5 0.1 2.7 1 1 2 3 3 3 2 Mitochondrial-associated sphingomyelin phosphodiesterase NSF PF02071.15 ETO03373.1 - 0.0061 16.8 12.6 82 4.5 0.1 6.6 6 0 0 6 6 6 0 Aromatic-di-Alanine (AdAR) repeat Sel1 PF08238.7 ETO03373.1 - 0.017 15.7 13.9 18 6.1 0.1 5.7 6 0 0 6 6 5 0 Sel1 repeat MM_CoA_mutase PF01642.17 ETO03373.1 - 0.056 11.5 0.5 7.9 4.4 0.0 3.0 1 1 2 3 3 3 0 Methylmalonyl-CoA mutase OEP PF02321.13 ETO03373.1 - 0.064 12.8 13.8 0.28 10.7 0.2 4.0 2 1 3 5 5 5 0 Outer membrane efflux protein Sda PF08970.5 ETO03373.1 - 0.12 11.8 7.9 58 3.2 0.0 5.0 5 0 0 5 5 5 0 Sporulation inhibitor A DUF2959 PF11172.3 ETO03373.1 - 0.15 11.8 4.7 3.7 7.2 0.7 3.1 1 1 3 4 4 4 0 Protein of unknown function (DUF2959) Sec5 PF15469.1 ETO03373.1 - 0.31 10.7 17.8 4.2 7.0 0.2 5.0 5 0 0 5 5 5 0 Exocyst complex component Sec5 UPF0122 PF04297.9 ETO03373.1 - 0.35 10.9 9.4 15 5.6 0.1 5.1 4 2 2 6 6 6 0 Putative helix-turn-helix protein, YlxM / p13 like Tat PF00539.13 ETO03373.1 - 1.6 8.4 11.8 15 5.2 0.1 4.9 5 0 0 5 5 5 0 Transactivating regulatory protein (Tat) ATP-synt_E_2 PF08112.6 ETO03373.1 - 3.2 7.8 13.0 23 5.1 0.0 5.2 6 0 0 6 6 5 0 ATP synthase epsilon subunit DUF3573 PF12097.3 ETO03374.1 - 0.48 8.9 7.5 0.59 8.6 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) HTH_Tnp_IS630 PF01710.11 ETO03374.1 - 0.67 9.6 13.4 0.043 13.4 3.5 2.4 3 0 0 3 3 3 0 Transposase Cob_adeno_trans PF01923.13 ETO03374.1 - 9.6 5.9 7.3 10 5.8 0.7 2.2 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Ret_tiss PF10044.4 ETO03376.1 - 0.2 12.2 1.7 1.4 9.4 0.2 2.6 1 1 1 2 2 2 0 Retinal tissue protein SET PF00856.23 ETO03377.1 - 1.6e-05 25.2 0.3 3.8e-05 24.0 0.2 1.6 1 1 0 1 1 1 1 SET domain WD40 PF00400.27 ETO03381.1 - 5.6e-45 149.6 10.0 6e-11 41.7 0.0 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO03381.1 - 5e-09 34.8 0.4 0.067 11.3 0.2 3.7 1 1 2 3 3 3 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO03381.1 - 0.00071 19.3 0.5 1.6 8.5 0.2 3.4 2 1 1 3 3 3 3 Ciliary BBSome complex subunit 2, middle region Alpha-L-AF_C PF06964.7 ETO03381.1 - 0.071 12.8 0.0 0.16 11.7 0.0 1.5 1 1 0 1 1 1 0 Alpha-L-arabinofuranosidase C-terminus WD40 PF00400.27 ETO03382.1 - 9.3e-12 44.3 2.7 4.2e-11 42.2 1.2 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat Vfa1 PF08432.5 ETO03382.1 - 0.0003 20.8 6.8 0.0004 20.4 4.7 1.1 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Nup160 PF11715.3 ETO03382.1 - 0.00051 18.3 0.2 0.00057 18.1 0.1 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 DDHD PF02862.12 ETO03382.1 - 0.033 13.9 2.3 0.042 13.6 1.6 1.1 1 0 0 1 1 1 0 DDHD domain CENP-Q PF13094.1 ETO03382.1 - 0.11 12.5 6.5 0.15 12.0 4.5 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Atg14 PF10186.4 ETO03382.1 - 0.54 9.1 12.4 0.65 8.8 8.6 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Geminin PF07412.7 ETO03382.1 - 1.3 8.6 12.5 0.063 12.9 2.0 2.1 1 1 1 2 2 2 0 Geminin MCM PF00493.18 ETO03383.1 - 0.0032 16.3 0.1 0.0046 15.8 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family AAA PF00004.24 ETO03383.1 - 0.0038 17.4 0.2 0.2 11.8 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 ETO03383.1 - 0.01 14.7 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ResIII PF04851.10 ETO03383.1 - 0.022 14.5 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 ETO03383.1 - 0.041 14.0 0.1 0.14 12.2 0.0 1.9 1 1 1 2 2 2 0 AAA domain PhoH PF02562.11 ETO03383.1 - 0.048 12.9 0.0 0.074 12.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.22 ETO03383.1 - 0.064 13.5 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 ABC transporter SMP_2 PF10144.4 ETO03383.1 - 0.12 11.4 0.2 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin RR_TM4-6 PF06459.7 ETO03385.1 - 0.012 15.5 24.6 0.014 15.2 17.0 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Plasmodium_Vir PF05795.6 ETO03385.1 - 0.16 11.1 17.8 0.18 10.9 12.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CDC45 PF02724.9 ETO03385.1 - 0.21 9.5 26.4 0.23 9.4 18.3 1.2 1 0 0 1 1 1 0 CDC45-like protein SprA-related PF12118.3 ETO03385.1 - 0.23 10.7 26.4 0.28 10.4 18.3 1.1 1 0 0 1 1 1 0 SprA-related family CobT PF06213.7 ETO03385.1 - 0.35 9.9 22.3 0.44 9.6 15.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DDHD PF02862.12 ETO03385.1 - 0.52 10.0 18.4 0.73 9.5 12.8 1.2 1 0 0 1 1 1 0 DDHD domain NAM-associated PF14303.1 ETO03385.1 - 1.6 9.0 32.0 1.9 8.7 22.2 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain MIP-T3 PF10243.4 ETO03385.1 - 1.7 7.0 37.8 2.1 6.7 26.2 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Serinc PF03348.10 ETO03385.1 - 2.3 6.8 8.4 2.8 6.5 5.8 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Spore_coat_CotO PF14153.1 ETO03385.1 - 2.7 7.4 28.3 3.7 6.9 19.6 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Rtf2 PF04641.7 ETO03385.1 - 3.1 6.9 25.1 4.1 6.5 17.4 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger GAGA_bind PF06217.7 ETO03385.1 - 3.5 7.5 19.9 4.4 7.1 13.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family FLO_LFY PF01698.11 ETO03385.1 - 3.9 6.2 20.2 4.8 5.9 14.0 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein eIF-3_zeta PF05091.7 ETO03385.1 - 3.9 5.9 18.7 4.3 5.8 13.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RRN3 PF05327.6 ETO03385.1 - 4.2 5.3 16.5 4.9 5.1 11.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RNA_pol_Rpb1_5 PF04998.12 ETO03385.1 - 4.5 6.4 9.7 5.3 6.2 6.7 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Herpes_UL87 PF03043.9 ETO03385.1 - 4.9 5.4 8.7 5.6 5.2 6.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family Raftlin PF15250.1 ETO03385.1 - 5.5 5.4 15.2 6.3 5.2 10.6 1.2 1 0 0 1 1 1 0 Raftlin Glyco_transf_8 PF01501.15 ETO03385.1 - 7.1 5.8 6.9 16 4.6 4.8 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 8 Nop53 PF07767.6 ETO03385.1 - 7.8 5.3 37.6 8.2 5.3 26.1 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF2422 PF10337.4 ETO03385.1 - 9.1 4.9 8.5 9.7 4.8 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Kelch_4 PF13418.1 ETO03386.1 - 0.0038 16.9 1.3 2.1 8.1 0.3 2.9 2 1 0 2 2 2 2 Galactose oxidase, central domain DUF2107 PF09880.4 ETO03387.1 - 0.031 14.1 0.2 0.051 13.4 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2107) DUF1829 PF08862.5 ETO03387.1 - 0.071 13.3 0.5 1.1 9.5 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF1829 Pkinase PF00069.20 ETO03389.1 - 4.5e-08 32.5 0.0 6.9e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO03389.1 - 0.00034 19.7 0.0 0.00066 18.8 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase DUF3413 PF11893.3 ETO03389.1 - 0.032 13.1 0.3 0.055 12.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) Kelch_6 PF13964.1 ETO03391.1 - 0.00089 19.3 1.5 0.015 15.4 0.0 3.5 4 1 1 5 5 5 1 Kelch motif Kelch_4 PF13418.1 ETO03391.1 - 0.0011 18.6 0.5 0.062 13.0 0.0 3.6 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO03391.1 - 0.0027 17.4 0.9 0.017 14.8 0.2 2.6 2 0 0 2 2 2 1 Kelch motif Na_K-ATPase PF00287.13 ETO03391.1 - 0.011 14.4 0.0 0.018 13.8 0.0 1.3 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain Kelch_1 PF01344.20 ETO03391.1 - 0.015 14.8 2.2 0.062 12.8 0.1 3.0 4 0 0 4 4 4 0 Kelch motif DUF987 PF06174.6 ETO03391.1 - 0.033 13.6 0.0 0.077 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF987) WD40 PF00400.27 ETO03392.1 - 3e-20 71.2 5.6 2.3e-11 43.1 0.8 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO03392.1 - 2.1e-06 26.1 6.6 2.2e-05 22.8 0.1 2.9 2 1 1 3 3 3 2 Nucleoporin Nup120/160 DUF4525 PF15027.1 ETO03392.1 - 0.012 15.1 0.3 0.012 15.1 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) DUF3573 PF12097.3 ETO03392.1 - 4.7 5.7 16.6 93 1.4 11.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) DUF3713 PF12506.3 ETO03394.1 - 0.014 15.4 1.7 0.32 11.0 1.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3713) Ank_4 PF13637.1 ETO03395.1 - 0.0032 17.9 0.2 0.011 16.2 0.1 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO03395.1 - 0.056 13.7 0.0 0.067 13.5 0.0 1.5 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.25 ETO03395.1 - 0.1 12.4 0.2 0.48 10.3 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeat NOSIC PF08060.8 ETO03396.1 - 0.11 12.2 0.4 0.29 10.9 0.0 1.9 2 0 0 2 2 2 0 NOSIC (NUC001) domain PUF PF00806.14 ETO03398.1 - 0.026 13.9 0.0 2.1 7.9 0.0 2.9 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat Inos-1-P_synth PF01658.12 ETO03398.1 - 0.079 12.7 1.2 0.084 12.7 0.1 1.6 2 0 0 2 2 2 0 Myo-inositol-1-phosphate synthase DUF4014 PF13198.1 ETO03399.1 - 0.0084 16.5 0.1 0.019 15.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4014) Kelch_1 PF01344.20 ETO03400.1 - 2.4e-09 36.5 0.8 3.6e-06 26.4 0.2 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO03400.1 - 3e-08 33.4 1.0 0.00013 21.9 0.0 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO03400.1 - 1.8e-05 24.3 0.4 0.11 12.3 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO03400.1 - 0.0015 18.6 0.1 0.21 11.7 0.0 3.1 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO03400.1 - 0.0026 17.6 0.4 0.14 12.1 0.1 2.9 2 0 0 2 2 2 1 Kelch motif CCDC155 PF14662.1 ETO03400.1 - 0.0056 16.3 3.1 0.0089 15.6 2.1 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 Cluap1 PF10234.4 ETO03400.1 - 0.0093 15.1 2.6 0.014 14.6 1.8 1.1 1 0 0 1 1 1 1 Clusterin-associated protein-1 DUF948 PF06103.6 ETO03400.1 - 0.049 13.4 5.0 0.17 11.7 1.7 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4501 PF14946.1 ETO03403.1 - 0.17 11.3 0.7 0.29 10.5 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4501) TLD PF07534.11 ETO03404.1 - 5.7e-21 74.9 2.1 1.3e-20 73.7 1.5 1.7 1 0 0 1 1 1 1 TLD NPV_P10 PF05531.7 ETO03404.1 - 0.0013 18.8 1.9 0.0013 18.8 1.3 2.5 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein Tox-ODYAM1 PF15642.1 ETO03404.1 - 0.015 14.0 8.3 0.023 13.3 5.7 1.3 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus OmpH PF03938.9 ETO03404.1 - 0.17 11.7 14.7 1.3 8.9 5.4 2.6 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Iron_permease PF04120.7 ETO03404.1 - 2.8 7.5 10.8 2.3 7.8 5.0 2.3 1 1 1 2 2 2 0 Low affinity iron permease PPR_2 PF13041.1 ETO03405.1 - 2.1e-14 53.1 1.0 1.8e-11 43.8 0.1 3.1 2 1 1 3 3 3 2 PPR repeat family PPR_1 PF12854.2 ETO03405.1 - 9e-12 44.2 0.3 2.7e-05 23.5 0.0 3.4 3 0 0 3 3 3 3 PPR repeat PPR_3 PF13812.1 ETO03405.1 - 1.1e-11 44.0 0.1 1.3e-05 25.0 0.0 3.1 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.15 ETO03405.1 - 1.3e-11 43.5 2.1 2e-06 27.3 0.0 3.2 4 0 0 4 4 4 2 PPR repeat ATP13 PF12921.2 ETO03405.1 - 0.029 13.7 0.7 1.7 7.9 0.1 2.6 1 1 1 2 2 2 0 Mitochondrial ATPase expression DUF4080 PF13311.1 ETO03407.1 - 1.7 8.6 5.3 0.19 11.7 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4080) Nop14 PF04147.7 ETO03407.1 - 1.8 6.3 35.5 2.2 6.0 24.6 1.1 1 0 0 1 1 1 0 Nop14-like family MIP-T3 PF10243.4 ETO03407.1 - 3.8 5.8 25.5 4.6 5.5 17.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 APG12 PF04110.8 ETO03409.1 - 0.074 13.2 0.7 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DrsE_2 PF13686.1 ETO03409.1 - 0.42 10.3 3.2 0.17 11.6 0.5 1.5 2 0 0 2 2 2 0 DsrE/DsrF/DrsH-like family DUF3413 PF11893.3 ETO03411.1 - 0.078 11.8 4.2 0.14 11.0 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) Cnd1 PF12717.2 ETO03412.1 - 0.014 15.2 1.6 0.021 14.6 1.1 1.4 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.5 ETO03412.1 - 0.029 13.9 0.4 0.24 10.9 0.1 2.0 1 1 1 2 2 2 0 TATA-binding protein interacting (TIP20) Tnp_P_element_C PF12596.3 ETO03414.1 - 0.22 11.8 0.0 0.22 11.8 0.0 2.2 2 1 0 2 2 2 0 87kDa Transposase HEAT_2 PF13646.1 ETO03415.1 - 6.7e-05 23.0 0.0 0.023 14.9 0.0 2.1 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 ETO03415.1 - 8.3e-05 22.9 0.0 2.8 8.5 0.0 3.0 3 0 0 3 3 3 2 HEAT-like repeat HEAT PF02985.17 ETO03415.1 - 0.0042 17.0 0.0 8.2 6.8 0.0 3.6 3 1 0 3 3 3 1 HEAT repeat Dopey_N PF04118.9 ETO03415.1 - 0.081 11.6 0.0 0.094 11.4 0.0 1.2 1 0 0 1 1 1 0 Dopey, N-terminal CLASP_N PF12348.3 ETO03415.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.5 1 1 0 1 1 1 0 CLASP N terminal rve PF00665.21 ETO03417.1 - 2.7e-15 56.5 0.0 6.8e-15 55.2 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 ETO03417.1 - 0.0036 16.7 0.0 0.0085 15.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Pkinase PF00069.20 ETO03418.1 - 7.6e-07 28.5 1.7 1.2e-06 27.8 0.8 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO03418.1 - 3.2e-05 23.1 2.3 6.9e-05 22.0 1.5 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3949 PF13133.1 ETO03419.1 - 0.95 9.7 5.7 0.29 11.3 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3949) Ldh_1_N PF00056.18 ETO03420.1 - 1.2e-20 73.7 0.3 8.4e-20 71.0 0.2 1.9 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain zf-TRAF PF02176.13 ETO03422.1 - 2.1e-05 24.8 3.9 2.1e-05 24.8 2.7 2.9 3 1 0 3 3 3 1 TRAF-type zinc finger RVT_1 PF00078.22 ETO03423.1 - 3e-13 49.6 0.2 3.6e-12 46.0 0.1 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TPR_12 PF13424.1 ETO03425.1 - 1.1e-37 127.8 4.3 1.2e-23 82.8 0.3 2.7 2 1 0 3 3 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO03425.1 - 1.6e-25 88.2 0.0 2.7e-08 33.4 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO03425.1 - 3.2e-24 83.4 17.1 6.4e-09 35.0 0.2 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO03425.1 - 1.3e-22 79.1 7.2 1.2e-16 60.1 0.4 2.6 2 0 0 2 2 2 2 TPR repeat TPR_7 PF13176.1 ETO03425.1 - 1.5e-22 77.5 2.3 5.2e-08 32.0 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO03425.1 - 6.5e-19 66.2 12.1 3e-06 26.7 0.1 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO03425.1 - 3.7e-18 63.8 22.9 2.4e-08 33.1 1.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO03425.1 - 2.1e-12 46.2 4.9 0.0004 20.3 0.1 4.2 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO03425.1 - 3.7e-10 40.1 0.0 5.7e-05 23.6 0.0 3.2 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO03425.1 - 9.9e-09 35.1 4.9 0.12 12.8 0.2 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO03425.1 - 2.3e-06 27.7 0.0 1.6 9.5 0.0 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO03425.1 - 2.1e-05 24.5 7.5 0.0045 17.0 0.7 3.0 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO03425.1 - 4.3e-05 23.7 0.8 0.0044 17.3 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_3 PF07720.7 ETO03425.1 - 0.00075 19.2 19.1 0.098 12.4 0.7 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat DUF627 PF04781.7 ETO03425.1 - 0.0063 16.1 2.6 1.1 8.9 0.0 3.3 2 1 1 3 3 3 1 Protein of unknown function (DUF627) MIT PF04212.13 ETO03425.1 - 0.0083 15.9 13.3 0.36 10.7 0.4 3.5 2 1 1 3 3 3 2 MIT (microtubule interacting and transport) domain FATC PF02260.15 ETO03425.1 - 0.028 13.8 0.6 9.2 5.8 0.0 3.2 3 0 0 3 3 3 0 FATC domain Sel1 PF08238.7 ETO03425.1 - 0.037 14.6 7.5 0.23 12.1 0.0 2.9 3 0 0 3 3 2 0 Sel1 repeat PPR PF01535.15 ETO03425.1 - 0.055 13.4 9.7 0.14 12.1 0.1 4.6 5 0 0 5 5 5 0 PPR repeat ATP-synt_F PF01990.12 ETO03425.1 - 0.059 13.7 0.1 0.13 12.6 0.1 1.5 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit RPN7 PF10602.4 ETO03425.1 - 0.62 9.4 4.5 11 5.4 0.2 2.7 1 1 2 3 3 3 0 26S proteasome subunit RPN7 Ubiq-assoc PF09145.5 ETO03425.1 - 8.2 6.3 10.5 11 5.9 0.1 4.2 4 0 0 4 4 4 0 Ubiquitin-associated NACHT PF05729.7 ETO03427.1 - 2.4e-19 69.6 0.0 7.6e-19 67.9 0.0 1.9 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 ETO03427.1 - 3.2e-05 22.9 0.6 6.6e-05 21.9 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain Sec23_helical PF04815.10 ETO03427.1 - 0.00024 20.4 3.5 0.02 14.3 0.1 2.7 2 0 0 2 2 2 2 Sec23/Sec24 helical domain AAA_16 PF13191.1 ETO03427.1 - 0.02 14.8 0.0 0.048 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 ETO03427.1 - 0.045 14.0 0.0 0.14 12.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 ETO03427.1 - 0.05 13.3 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 ETO03427.1 - 0.066 13.3 0.0 0.57 10.3 0.0 2.4 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 ETO03427.1 - 0.076 12.1 0.0 0.49 9.5 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI HEAT_2 PF13646.1 ETO03428.1 - 3e-17 62.6 0.0 2.1e-07 31.0 0.0 5.8 2 2 4 7 7 7 6 HEAT repeats HEAT PF02985.17 ETO03428.1 - 7.3e-15 53.6 0.1 0.067 13.3 0.0 8.4 9 0 0 9 9 9 4 HEAT repeat HEAT_EZ PF13513.1 ETO03428.1 - 5.7e-07 29.8 0.0 12 6.5 0.0 6.0 5 2 2 7 7 7 1 HEAT-like repeat Cnd1 PF12717.2 ETO03428.1 - 1.8e-05 24.6 26.1 0.0052 16.6 7.0 4.3 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 ETO03428.1 - 0.0012 18.7 5.9 0.42 10.5 0.1 4.3 3 1 1 4 4 4 2 Protein of unknown function (DUF2435) Ank_5 PF13857.1 ETO03428.1 - 0.0029 17.7 0.5 0.013 15.7 0.4 2.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 ETO03428.1 - 0.0037 17.0 0.1 0.013 15.2 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat Ank PF00023.25 ETO03429.1 - 2.5e-05 23.8 0.0 9.7e-05 21.9 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 ETO03429.1 - 0.00081 19.4 0.0 0.0026 17.8 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.1 ETO03429.1 - 0.0025 18.0 0.0 0.0076 16.4 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DNA_pol_E_B PF04042.11 ETO03429.1 - 0.03 13.5 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B ubiquitin PF00240.18 ETO03430.1 - 0.16 11.3 1.3 0.29 10.5 0.1 2.0 2 0 0 2 2 2 0 Ubiquitin family DUF2146 PF10220.4 ETO03431.1 - 9e-05 20.6 12.2 0.0001 20.4 8.4 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2146) MIP-T3 PF10243.4 ETO03431.1 - 0.001 17.6 34.0 0.001 17.6 23.6 1.0 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF1777 PF08648.7 ETO03431.1 - 0.026 14.2 26.1 0.031 14.0 18.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Transformer PF06495.6 ETO03431.1 - 0.13 12.1 11.9 0.18 11.6 8.2 1.3 1 0 0 1 1 1 0 Fruit fly transformer protein SAPS PF04499.10 ETO03431.1 - 0.18 10.3 12.5 0.17 10.4 8.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mem_trans PF03547.13 ETO03431.1 - 0.21 9.8 3.4 0.18 10.0 2.3 1.1 1 0 0 1 1 1 0 Membrane transport protein Neur_chan_memb PF02932.11 ETO03431.1 - 0.34 10.7 10.0 0.35 10.7 6.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SOBP PF15279.1 ETO03431.1 - 3.6 7.8 11.0 3.5 7.9 7.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4002 PF13164.1 ETO03432.1 - 0.054 13.4 0.1 0.079 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4002) WD40 PF00400.27 ETO03433.1 - 1.2e-19 69.4 0.2 1.3e-12 47.0 0.1 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Pentapeptide_4 PF13599.1 ETO03433.1 - 2.6e-05 23.9 1.6 4.7e-05 23.1 1.1 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 ETO03433.1 - 6.4e-05 22.7 1.6 0.00014 21.6 1.1 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETO03433.1 - 0.001 18.2 3.6 0.17 11.1 0.2 2.5 2 1 1 3 3 3 2 Pentapeptide repeats (8 copies) Gmad1 PF10647.4 ETO03433.1 - 0.011 15.2 0.0 1.7 8.0 0.0 2.3 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain DUF3379 PF11859.3 ETO03433.1 - 0.029 13.5 0.1 0.036 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) DUF2984 PF11203.3 ETO03434.1 - 0.049 13.7 0.0 0.053 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2984) Chlor_dismutase PF06778.7 ETO03436.1 - 0.0035 17.0 2.1 0.0057 16.3 1.4 1.3 1 0 0 1 1 1 1 Chlorite dismutase DUF4613 PF15390.1 ETO03436.1 - 2.8 6.0 13.5 4.4 5.3 9.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF2024 PF09630.5 ETO03439.1 - 0.037 13.7 0.8 0.36 10.5 0.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF2024) Myosin_tail_1 PF01576.14 ETO03440.1 - 4e-07 28.1 26.2 8.6e-07 27.0 18.1 1.5 1 1 0 1 1 1 1 Myosin tail APG6 PF04111.7 ETO03440.1 - 0.0065 15.5 32.9 0.031 13.3 17.6 2.0 1 1 1 2 2 2 2 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 ETO03440.1 - 0.0089 15.8 31.6 0.46 10.3 5.4 2.8 1 1 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.3 ETO03440.1 - 0.013 12.8 23.5 0.016 12.5 16.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Rootletin PF15035.1 ETO03440.1 - 0.015 15.2 25.5 0.021 14.8 17.7 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion GAS PF13851.1 ETO03440.1 - 0.016 14.4 34.9 0.27 10.4 10.8 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding XisH PF08814.5 ETO03440.1 - 0.025 14.6 1.1 0.046 13.7 0.7 1.5 1 1 0 1 1 1 0 XisH protein ATG16 PF08614.6 ETO03440.1 - 0.096 12.4 31.8 0.55 10.0 6.1 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Filament PF00038.16 ETO03440.1 - 0.1 12.0 26.5 0.19 11.1 18.4 1.4 1 1 0 1 1 1 0 Intermediate filament protein EzrA PF06160.7 ETO03440.1 - 0.11 10.6 23.8 0.33 9.0 16.5 1.7 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Chordopox_L2 PF05803.7 ETO03440.1 - 0.12 12.0 1.4 0.21 11.2 0.3 1.9 2 0 0 2 2 1 0 Chordopoxvirus L2 protein CALCOCO1 PF07888.6 ETO03440.1 - 0.16 10.2 19.7 0.19 9.9 13.6 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3450 PF11932.3 ETO03440.1 - 0.17 11.1 25.9 0.19 10.9 6.3 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) DUF722 PF05263.6 ETO03440.1 - 0.19 11.8 16.0 0.4 10.8 6.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF722) TPR_MLP1_2 PF07926.7 ETO03440.1 - 0.26 11.0 33.9 0.43 10.3 7.3 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Mnd1 PF03962.10 ETO03440.1 - 0.27 10.8 26.7 0.042 13.4 11.1 2.1 1 1 1 2 2 2 0 Mnd1 family DUF489 PF04356.7 ETO03440.1 - 0.29 10.6 10.8 2.4 7.6 3.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF489) MAD PF05557.8 ETO03440.1 - 0.32 9.0 28.3 1.2 7.1 19.6 1.6 1 1 0 1 1 1 0 Mitotic checkpoint protein ERM PF00769.14 ETO03440.1 - 0.39 10.2 25.4 1.5 8.3 17.6 1.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Reo_sigmaC PF04582.7 ETO03440.1 - 0.4 9.8 4.0 0.31 10.1 1.6 1.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein MA3 PF02847.12 ETO03440.1 - 0.55 9.9 5.0 0.96 9.1 0.8 2.3 1 1 1 2 2 2 0 MA3 domain DUF4164 PF13747.1 ETO03440.1 - 0.56 10.3 17.2 0.083 13.0 1.8 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Taxilin PF09728.4 ETO03440.1 - 0.64 9.0 31.1 1.1 8.2 21.5 1.3 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Imm46 PF15585.1 ETO03440.1 - 0.72 9.9 7.9 0.76 9.8 1.5 2.3 1 1 1 2 2 2 0 Immunity protein 46 DUF342 PF03961.8 ETO03440.1 - 0.99 7.7 28.7 0.12 10.7 10.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF4200 PF13863.1 ETO03440.1 - 1 9.3 32.0 0.17 11.8 14.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) IncA PF04156.9 ETO03440.1 - 1 8.9 29.8 1.4 8.4 10.0 2.1 1 1 1 2 2 2 0 IncA protein DUF4201 PF13870.1 ETO03440.1 - 1.3 8.4 31.7 0.3 10.4 10.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Seryl_tRNA_N PF02403.17 ETO03440.1 - 1.4 8.9 26.0 0.3 11.1 9.4 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3642 PF12182.3 ETO03440.1 - 1.4 9.3 12.0 0.17 12.3 0.9 2.9 2 1 1 3 3 3 0 Bacterial lipoprotein Mod_r PF07200.8 ETO03440.1 - 1.8 8.5 26.5 0.24 11.3 8.0 2.6 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Ax_dynein_light PF10211.4 ETO03440.1 - 2.2 8.1 31.4 4.4 7.0 11.4 2.8 1 1 1 2 2 2 0 Axonemal dynein light chain DUF4618 PF15397.1 ETO03440.1 - 2.3 7.5 28.2 0.53 9.5 8.6 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) DUF2968 PF11180.3 ETO03440.1 - 3.5 6.9 22.0 1.5 8.1 3.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF1079 PF06435.6 ETO03440.1 - 3.7 7.5 7.8 9.6 6.2 0.1 3.2 3 0 0 3 3 2 0 Repeat of unknown function (DUF1079) ADIP PF11559.3 ETO03440.1 - 4.8 7.0 34.8 1.8 8.4 6.3 3.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF812 PF05667.6 ETO03440.1 - 5.4 5.4 27.2 9.5 4.5 18.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DivIVA PF05103.8 ETO03440.1 - 5.6 7.0 28.4 6.8 6.7 12.2 2.8 1 1 1 2 2 2 0 DivIVA protein DUF948 PF06103.6 ETO03440.1 - 6.7 6.6 14.8 0.86 9.5 2.7 2.4 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Cortex-I_coil PF09304.5 ETO03440.1 - 6.8 6.7 26.9 16 5.5 10.3 2.9 1 1 1 2 2 2 0 Cortexillin I, coiled coil Mito_fiss_reg PF05308.6 ETO03440.1 - 7.5 5.8 10.5 7.3 5.8 6.2 1.7 1 1 0 1 1 1 0 Mitochondrial fission regulator TMCO5 PF14992.1 ETO03440.1 - 7.8 5.5 27.8 20 4.1 19.3 1.6 1 1 0 1 1 1 0 TMCO5 family Syntaxin PF00804.20 ETO03440.1 - 9 6.5 28.2 2.6 8.2 5.0 2.9 1 1 2 3 3 3 0 Syntaxin DUF3802 PF12290.3 ETO03441.1 - 0.084 13.1 0.6 0.18 12.1 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3802) U-box PF04564.10 ETO03443.1 - 3.7e-14 52.4 0.1 1e-13 50.9 0.1 1.8 1 1 0 1 1 1 1 U-box domain TPR_12 PF13424.1 ETO03446.1 - 1.2e-29 102.0 4.5 3.7e-16 58.8 0.1 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO03446.1 - 1.1e-18 65.9 12.8 1.9e-06 27.2 0.0 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO03446.1 - 8e-17 59.7 9.3 8.9e-07 28.3 1.1 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO03446.1 - 1.4e-15 56.6 8.2 9.2e-09 34.8 0.6 2.4 1 1 0 2 2 2 2 TPR repeat TPR_10 PF13374.1 ETO03446.1 - 1.2e-13 50.4 0.0 0.00063 19.5 0.0 3.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO03446.1 - 1.8e-13 49.2 15.9 5.8e-05 22.5 0.1 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO03446.1 - 1.2e-12 46.5 1.2 0.0013 18.3 0.0 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO03446.1 - 1.6e-09 36.8 0.1 6e-05 22.2 0.0 3.1 3 0 0 3 3 3 2 SHNi-TPR TPR_16 PF13432.1 ETO03446.1 - 1.3e-07 32.0 0.1 0.0037 17.8 0.0 2.2 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO03446.1 - 8.1e-07 28.7 3.5 0.022 14.9 0.2 3.3 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO03446.1 - 3.5e-06 27.1 2.8 0.018 15.4 0.4 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO03446.1 - 9.1e-05 22.5 3.7 0.0029 17.6 2.3 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 ETO03446.1 - 0.00039 20.7 0.0 2.3 9.0 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF1120 PF06551.7 ETO03446.1 - 0.00048 20.4 0.0 0.71 10.1 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1120) TPR_19 PF14559.1 ETO03446.1 - 0.0029 17.8 0.4 1 9.7 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat SNAP PF14938.1 ETO03446.1 - 0.007 15.5 1.1 0.013 14.6 0.8 1.4 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP DUF627 PF04781.7 ETO03446.1 - 0.037 13.6 0.3 4.9 6.8 0.0 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF627) RPN7 PF10602.4 ETO03446.1 - 0.11 11.9 1.5 3.7 6.8 0.0 2.2 2 1 0 2 2 2 0 26S proteasome subunit RPN7 Inhibitor_I29 PF08246.7 ETO03446.1 - 0.12 12.6 2.2 4.6 7.5 0.0 2.9 2 1 1 3 3 3 0 Cathepsin propeptide inhibitor domain (I29) UVR PF02151.14 ETO03446.1 - 0.98 9.0 5.1 1.2 8.7 0.2 3.1 3 1 1 4 4 4 0 UvrB/uvrC motif WD40 PF00400.27 ETO03447.1 - 7.5e-50 165.1 19.5 1.5e-11 43.7 0.0 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO03447.1 - 4.4e-08 31.7 3.5 0.042 11.9 0.0 4.7 1 1 2 4 4 4 4 Nucleoporin Nup120/160 WD40 PF00400.27 ETO03448.1 - 7.8e-106 342.5 35.7 9.5e-12 44.3 0.1 10.2 10 0 0 10 10 10 10 WD domain, G-beta repeat Nup160 PF11715.3 ETO03448.1 - 2.2e-09 35.9 16.2 0.41 8.7 0.0 8.1 1 1 7 8 8 8 5 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO03448.1 - 4.3e-08 33.0 2.4 0.0018 18.0 0.1 4.8 1 1 3 5 5 5 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO03448.1 - 3.8e-06 26.4 19.7 1.1 8.9 0.1 7.8 8 0 0 8 8 8 3 WD40-like Beta Propeller Repeat BBS2_Mid PF14783.1 ETO03448.1 - 0.00015 21.5 1.1 1.9 8.2 0.0 6.0 6 1 0 7 7 7 1 Ciliary BBSome complex subunit 2, middle region Cytochrom_D1 PF02239.11 ETO03448.1 - 0.006 14.9 3.1 0.13 10.5 0.1 3.6 2 1 1 3 3 3 1 Cytochrome D1 heme domain Resistin PF06954.6 ETO03448.1 - 0.012 15.8 5.0 14 6.0 0.0 5.3 5 2 2 7 7 7 0 Resistin DUF2436 PF10365.4 ETO03448.1 - 0.018 14.6 1.1 12 5.5 0.0 3.9 2 1 1 3 3 3 0 Domain of unknown function (DUF2436) Mid2 PF04478.7 ETO03448.1 - 0.35 10.2 9.1 0.4 10.0 0.1 4.5 4 2 2 6 6 6 0 Mid2 like cell wall stress sensor Kelch_4 PF13418.1 ETO03449.1 - 0.00021 20.9 0.1 0.081 12.7 0.0 3.2 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO03449.1 - 0.00045 20.2 3.9 0.0089 16.1 0.1 3.8 3 1 1 4 4 4 1 Kelch motif Kelch_1 PF01344.20 ETO03449.1 - 0.001 18.5 0.8 0.025 14.1 0.2 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 ETO03449.1 - 0.093 12.7 0.6 4.2 7.4 0.0 3.0 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.10 ETO03449.1 - 0.1 12.3 0.1 1.7 8.5 0.0 2.6 2 0 0 2 2 2 0 Kelch motif Di19_C PF14571.1 ETO03450.1 - 0.14 12.4 2.1 0.17 12.1 1.4 1.1 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal PPR_2 PF13041.1 ETO03452.1 - 0.0052 16.7 0.1 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 PPR repeat family PPR PF01535.15 ETO03452.1 - 0.018 14.9 0.1 0.052 13.5 0.0 1.8 2 0 0 2 2 2 0 PPR repeat FAA_hydrolase PF01557.13 ETO03453.1 - 2.2e-29 102.5 0.0 2.5e-29 102.3 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family tRNA-synt_1c PF00749.16 ETO03454.1 - 1.3e-34 119.2 0.0 1.3e-34 119.2 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain P63C PF10546.4 ETO03454.1 - 0.039 13.8 0.1 0.094 12.6 0.0 1.7 1 0 0 1 1 1 0 P63C domain Vfa1 PF08432.5 ETO03454.1 - 9.5 6.2 12.0 15 5.5 8.3 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 YaaC PF14175.1 ETO03455.1 - 0.0029 16.6 6.2 0.0035 16.3 4.3 1.1 1 0 0 1 1 1 1 YaaC-like Protein Menin PF05053.8 ETO03455.1 - 0.25 9.4 12.6 0.34 9.0 8.7 1.3 1 0 0 1 1 1 0 Menin Pox_Ag35 PF03286.9 ETO03455.1 - 1 8.8 12.8 1.4 8.3 8.9 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Zip PF02535.17 ETO03455.1 - 1.9 7.4 3.9 2.1 7.2 2.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3464 PF11947.3 ETO03455.1 - 4.7 6.6 6.3 92 2.4 4.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) NOA36 PF06524.7 ETO03455.1 - 4.8 6.3 16.6 6.1 6.0 11.5 1.1 1 0 0 1 1 1 0 NOA36 protein Tetraspannin PF00335.15 ETO03455.1 - 7 5.8 8.4 8.2 5.6 5.8 1.2 1 0 0 1 1 1 0 Tetraspanin family SIT PF15330.1 ETO03456.1 - 0.11 12.6 4.9 0.19 11.8 3.4 1.4 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT XAP5 PF04921.9 ETO03456.1 - 1.5 8.3 12.4 2.1 7.8 8.6 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator Apis_Csd PF11671.3 ETO03456.1 - 6.3 6.5 20.1 0.21 11.3 9.8 1.7 1 1 1 2 2 2 0 Complementary sex determiner protein DUF1754 PF08555.5 ETO03456.1 - 8 7.1 19.2 3.5 8.2 11.2 2.0 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Phage_int_SAM_3 PF14659.1 ETO03458.1 - 0.28 11.4 2.0 12 6.2 0.5 2.3 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain MOR2-PAG1_C PF14225.1 ETO03459.1 - 0.037 13.7 1.1 0.29 10.8 0.1 2.1 1 1 1 2 2 2 0 Cell morphogenesis C-terminal CTK3 PF12243.3 ETO03459.1 - 0.081 12.5 3.4 0.16 11.6 1.5 2.0 1 1 1 2 2 2 0 CTD kinase subunit gamma CTK3 Lac_bphage_repr PF06543.7 ETO03460.1 - 0.23 11.0 5.0 0.35 10.4 1.9 2.3 2 1 1 3 3 3 0 Lactococcus bacteriophage repressor DUF2415 PF10313.4 ETO03463.1 - 0.072 12.7 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) TRAPPC-Trs85 PF12739.2 ETO03463.1 - 0.098 11.2 0.0 0.098 11.2 0.0 1.1 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit HSP70 PF00012.15 ETO03464.1 - 0.00014 19.9 0.0 0.12 10.2 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein INCENP_ARK-bind PF03941.10 ETO03464.1 - 0.013 15.3 0.2 0.028 14.2 0.0 1.7 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region Peptidase_M22 PF00814.20 ETO03464.1 - 0.035 13.5 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 Glycoprotease family MBOAT PF03062.14 ETO03465.1 - 0.055 12.5 1.3 0.061 12.4 0.9 1.0 1 0 0 1 1 1 0 MBOAT, membrane-bound O-acyltransferase family DUF1616 PF07760.6 ETO03465.1 - 0.058 12.5 5.3 0.075 12.1 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) DUF2967 PF11179.3 ETO03466.1 - 0.5 9.8 4.5 0.63 9.4 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) NAD_binding_6 PF08030.7 ETO03466.1 - 1.5 8.6 6.5 1.8 8.4 4.5 1.1 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Sec62 PF03839.11 ETO03466.1 - 2.1 7.7 12.4 3 7.1 8.6 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 PMSI1 PF15322.1 ETO03466.1 - 2.3 7.2 4.8 2.9 6.8 3.3 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative FAM176 PF14851.1 ETO03466.1 - 7.8 6.1 8.4 12 5.5 5.8 1.3 1 0 0 1 1 1 0 FAM176 family DUF4364 PF14277.1 ETO03467.1 - 0.07 12.7 0.7 3.2 7.3 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4364) PQQ PF01011.16 ETO03467.1 - 0.11 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 PQQ enzyme repeat DUF2019 PF09450.5 ETO03467.1 - 0.13 12.1 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) Ank_2 PF12796.2 ETO03469.1 - 3.9e-12 46.3 0.3 1.5e-10 41.2 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO03469.1 - 1.1e-09 37.5 0.0 7.8e-06 25.4 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 ETO03469.1 - 1.4e-09 38.1 0.4 4.3e-08 33.4 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO03469.1 - 2.5e-09 36.4 0.3 0.00013 21.8 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 ETO03469.1 - 6.4e-06 26.2 0.2 5.6e-05 23.2 0.0 2.7 2 1 1 3 3 3 1 Ankyrin repeats (many copies) DUF1843 PF08898.5 ETO03469.1 - 0.033 14.2 0.0 0.074 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) Phage_hub_GP28 PF11110.3 ETO03469.1 - 0.46 10.1 3.3 5.7 6.5 0.1 2.6 3 0 0 3 3 3 0 Baseplate hub distal subunit HEAT PF02985.17 ETO03470.1 - 1.1e-10 40.6 0.0 0.0028 17.5 0.0 4.9 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 ETO03470.1 - 1.8e-10 40.9 0.0 3.1e-05 24.1 0.0 3.2 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 ETO03470.1 - 1.1e-07 32.1 0.0 0.0045 17.4 0.0 3.4 2 1 1 3 3 3 2 HEAT-like repeat Cnd1 PF12717.2 ETO03470.1 - 1.1e-06 28.6 1.3 7.4e-05 22.6 1.0 2.8 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 ETO03470.1 - 2.6e-05 24.5 1.1 0.007 16.7 0.0 2.8 2 1 1 3 3 3 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 ETO03470.1 - 5.4e-05 22.6 0.7 0.00095 18.5 0.1 2.1 1 1 1 2 2 2 1 CLASP N terminal TIP120 PF08623.5 ETO03470.1 - 0.00018 21.1 3.9 0.043 13.3 0.2 3.5 1 1 2 4 4 4 2 TATA-binding protein interacting (TIP20) DNA_alkylation PF08713.6 ETO03470.1 - 0.0004 19.9 0.0 0.00051 19.6 0.0 1.2 1 0 0 1 1 1 1 DNA alkylation repair enzyme DUF2608 PF11019.3 ETO03470.1 - 0.0057 15.6 0.2 0.47 9.4 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF2608) DUF3554 PF12074.3 ETO03470.1 - 0.011 15.2 1.2 0.16 11.3 1.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3554) HEAT_PBS PF03130.11 ETO03470.1 - 0.013 15.9 0.0 6.5 7.5 0.0 3.4 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat 14-3-3 PF00244.15 ETO03470.1 - 0.055 12.5 3.5 0.063 12.3 0.1 2.0 1 1 1 2 2 2 0 14-3-3 protein Rep_trans PF02486.14 ETO03470.1 - 0.075 12.5 0.5 0.18 11.2 0.1 1.8 2 0 0 2 2 2 0 Replication initiation factor UME PF08064.8 ETO03470.1 - 0.12 12.3 0.4 1 9.3 0.1 2.3 1 1 1 2 2 2 0 UME (NUC010) domain Tubulin_C PF03953.12 ETO03471.1 - 0.023 14.7 0.6 0.027 14.5 0.4 1.1 1 0 0 1 1 1 0 Tubulin C-terminal domain NMT_C PF02799.10 ETO03471.1 - 0.03 13.6 0.2 0.036 13.4 0.1 1.1 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Lipase_GDSL PF00657.17 ETO03471.1 - 0.12 12.1 0.2 0.14 12.0 0.2 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase UCH PF00443.24 ETO03472.1 - 6.4e-17 61.5 2.4 1e-16 60.8 1.7 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO03472.1 - 0.0032 16.9 8.7 0.048 13.0 6.1 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1539 PF07560.6 ETO03472.1 - 0.071 12.9 0.7 0.2 11.5 0.5 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) Pkinase PF00069.20 ETO03473.1 - 2.8e-31 108.6 0.1 4.8e-31 107.8 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO03473.1 - 1.1e-05 24.7 0.0 4.7e-05 22.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase RRM_1 PF00076.17 ETO03474.1 - 9e-64 211.0 5.4 8.9e-18 63.6 0.0 4.8 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO03474.1 - 1.2e-48 162.8 2.0 1.2e-12 47.5 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO03474.1 - 5.3e-30 103.0 3.4 2.6e-08 33.5 0.1 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETO03474.1 - 5.1e-07 29.3 0.1 0.046 13.4 0.0 4.4 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.6 ETO03474.1 - 1.4e-05 25.0 0.3 0.11 12.5 0.0 3.1 3 0 0 3 3 3 2 RNA binding domain UPF0020 PF01170.13 ETO03474.1 - 0.015 14.8 3.3 3.6 7.1 0.1 3.6 3 1 1 4 4 4 0 Putative RNA methylase family UPF0020 Corona_nucleoca PF00937.13 ETO03474.1 - 5.1 5.9 28.8 1.4 7.8 8.1 2.4 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein Zip PF02535.17 ETO03474.1 - 5.9 5.8 10.4 8.2 5.3 1.4 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter SprA-related PF12118.3 ETO03474.1 - 8.1 5.6 34.1 0.26 10.5 4.8 2.4 3 0 0 3 3 3 0 SprA-related family HTH_43 PF09904.4 ETO03477.1 - 0.19 11.5 2.2 0.54 10.0 0.7 2.4 2 1 1 3 3 3 0 Winged helix-turn helix PSI_PsaJ PF01701.13 ETO03479.1 - 3 7.6 4.7 17 5.2 0.1 2.4 2 0 0 2 2 2 0 Photosystem I reaction centre subunit IX / PsaJ CAAP1 PF15335.1 ETO03480.1 - 0.0023 18.1 2.5 0.42 10.8 0.1 3.2 3 0 0 3 3 3 2 Caspase activity and apoptosis inhibitor 1 DNA_pol3_gamma3 PF12169.3 ETO03480.1 - 0.11 12.2 0.1 0.31 10.7 0.1 1.8 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III HemX PF04375.9 ETO03480.1 - 0.17 10.4 0.1 0.17 10.4 0.0 2.2 3 0 0 3 3 3 0 HemX YojJ PF10372.4 ETO03480.1 - 3.6 7.5 8.3 0.33 10.8 0.2 3.3 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus DUF4093 PF13331.1 ETO03481.1 - 0.019 15.1 0.4 0.086 13.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4093) DUF2063 PF09836.4 ETO03481.1 - 0.044 13.7 0.2 0.84 9.6 0.0 3.1 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2063) Peptidase_M20 PF01546.23 ETO03482.1 - 4.1e-06 26.4 0.0 5.2e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 RNase_H PF00075.19 ETO03483.1 - 7.7e-09 35.9 0.0 0.00039 20.7 0.0 2.1 1 1 1 2 2 2 2 RNase H zf-RVT PF13966.1 ETO03484.1 - 0.014 15.6 0.1 0.024 14.9 0.1 1.4 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase RVT_1 PF00078.22 ETO03486.1 - 1e-08 34.7 0.2 2e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 ETO03486.1 - 0.016 14.1 1.5 0.19 10.6 0.1 2.1 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Ras PF00071.17 ETO03488.1 - 4.1e-08 32.7 0.1 2e-07 30.5 0.0 1.9 1 1 0 1 1 1 1 Ras family Miro PF08477.8 ETO03488.1 - 0.0014 19.0 0.1 0.0084 16.5 0.0 1.9 1 1 1 2 2 2 1 Miro-like protein ETRAMP PF09716.5 ETO03489.1 - 0.016 15.1 5.2 0.032 14.1 3.6 1.6 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) GAGA_bind PF06217.7 ETO03489.1 - 4 7.3 11.6 4.1 7.2 8.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2851 PF11013.3 ETO03491.1 - 0.042 12.5 0.6 0.086 11.5 0.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2851) AAR2 PF05282.6 ETO03491.1 - 0.065 12.1 1.2 0.082 11.8 0.8 1.1 1 0 0 1 1 1 0 AAR2 protein MadL PF03817.8 ETO03492.1 - 0.032 14.0 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 Malonate transporter MadL subunit Corona_S2 PF01601.11 ETO03493.1 - 0.0035 15.5 1.8 0.0047 15.0 1.2 1.2 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein Peptidase_C65 PF10275.4 ETO03493.1 - 0.0099 15.2 1.0 0.17 11.2 0.2 2.3 1 1 1 2 2 2 1 Peptidase C65 Otubain ParcG PF10274.4 ETO03493.1 - 0.021 14.7 0.1 0.057 13.3 0.0 1.7 2 0 0 2 2 2 0 Parkin co-regulated protein WD40 PF00400.27 ETO03494.1 - 6.1e-68 222.4 19.7 3.6e-11 42.4 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO03494.1 - 1.5e-10 39.8 2.0 0.12 10.5 0.0 5.6 1 1 5 6 6 6 4 Nucleoporin Nup120/160 Sec23_helical PF04815.10 ETO03494.1 - 0.002 17.5 0.9 0.0039 16.6 0.6 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain PQQ_2 PF13360.1 ETO03494.1 - 0.0092 15.4 0.0 1 8.8 0.0 2.8 2 1 1 3 3 3 2 PQQ-like domain DUF3601 PF12208.3 ETO03494.1 - 0.013 15.4 0.4 2.1 8.3 0.0 4.0 4 2 0 4 4 4 0 Domain of unknown function (DUF3601) Hom_end_hint PF05203.11 ETO03494.1 - 0.052 13.2 0.0 0.052 13.2 0.0 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint FBA PF04300.8 ETO03494.1 - 0.067 13.1 1.4 0.17 11.8 0.8 1.7 2 0 0 2 2 2 0 F-box associated region Exonuc_VII_L PF02601.10 ETO03494.1 - 0.62 9.1 10.0 0.84 8.7 6.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit GBP_C PF02841.9 ETO03494.1 - 1.1 8.4 14.7 1.4 8.0 10.2 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Prominin PF05478.6 ETO03494.1 - 4.9 4.5 8.1 6.3 4.2 5.6 1.1 1 0 0 1 1 1 0 Prominin zf-TRAF PF02176.13 ETO03495.1 - 3e-07 30.7 3.5 3e-07 30.7 2.4 2.1 2 0 0 2 2 2 1 TRAF-type zinc finger zf-H2C2_5 PF13909.1 ETO03495.1 - 0.0012 18.9 4.3 0.054 13.7 0.5 3.3 3 0 0 3 3 3 1 C2H2-type zinc-finger domain Sina PF03145.11 ETO03495.1 - 0.14 11.7 4.4 0.58 9.7 2.3 2.1 1 1 1 2 2 2 0 Seven in absentia protein family IL12p40_C PF10420.4 ETO03495.1 - 5.9 7.0 7.6 3.4 7.8 1.5 2.5 1 1 1 2 2 2 0 Cytokine interleukin-12p40 C-terminus WD40 PF00400.27 ETO03496.1 - 3.6e-22 77.3 5.5 1.4e-10 40.6 0.2 3.5 3 1 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO03496.1 - 0.015 13.4 0.1 2.9 5.9 0.0 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO03496.1 - 0.024 13.3 0.6 0.1 11.3 0.4 1.9 1 1 0 1 1 1 0 Nup133 N terminal like Borrelia_P83 PF05262.6 ETO03496.1 - 0.087 11.0 0.0 0.11 10.7 0.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein s48_45 PF07422.8 ETO03497.1 - 0.3 11.1 3.1 0.4 10.7 2.1 1.2 1 0 0 1 1 1 0 Sexual stage antigen s48/45 domain TMF_TATA_bd PF12325.3 ETO03498.1 - 0.00036 20.2 10.5 0.014 15.0 1.3 3.1 3 0 0 3 3 3 2 TATA element modulatory factor 1 TATA binding CASP_C PF08172.7 ETO03498.1 - 0.0059 15.6 0.7 0.0059 15.6 0.5 2.1 2 0 0 2 2 2 1 CASP C terminal V_ATPase_I PF01496.14 ETO03498.1 - 0.0074 14.2 4.1 0.0078 14.1 2.9 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family SpoIISA_toxin PF14171.1 ETO03498.1 - 0.017 14.3 0.8 0.017 14.3 0.6 2.1 1 1 1 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system HAUS6_N PF14661.1 ETO03498.1 - 0.065 12.5 5.7 0.1 11.9 4.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Spectrin PF00435.16 ETO03498.1 - 0.071 13.4 6.9 0.2 11.9 1.3 2.5 2 0 0 2 2 2 0 Spectrin repeat IncA PF04156.9 ETO03498.1 - 0.12 11.9 8.7 0.058 12.9 1.6 2.2 2 0 0 2 2 2 0 IncA protein HALZ PF02183.13 ETO03498.1 - 0.13 11.9 0.0 0.13 11.9 0.0 3.1 2 1 2 4 4 3 0 Homeobox associated leucine zipper DivIC PF04977.10 ETO03498.1 - 0.19 11.2 13.7 1.6 8.3 2.4 3.6 3 1 1 4 4 4 0 Septum formation initiator DUF3450 PF11932.3 ETO03498.1 - 0.38 9.9 5.4 0.19 10.9 1.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) MbeD_MobD PF04899.7 ETO03498.1 - 0.45 10.4 4.0 6.3 6.7 0.2 2.6 2 1 1 3 3 3 0 MbeD/MobD like DUF4446 PF14584.1 ETO03498.1 - 0.84 9.4 9.1 2.4 8.0 0.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Phage_GP20 PF06810.6 ETO03498.1 - 1.4 8.3 15.4 0.45 9.9 1.1 2.5 3 0 0 3 3 3 0 Phage minor structural protein GP20 Uso1_p115_C PF04871.8 ETO03498.1 - 1.9 8.4 8.8 0.77 9.6 2.4 2.7 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Nnf1 PF03980.9 ETO03498.1 - 1.9 8.4 12.3 1.8 8.6 3.5 2.9 3 1 0 3 3 2 0 Nnf1 Laminin_II PF06009.7 ETO03498.1 - 2.7 7.7 9.1 0.6 9.8 2.3 2.2 1 1 1 2 2 2 0 Laminin Domain II Cep57_CLD_2 PF14197.1 ETO03498.1 - 3.6 7.5 9.6 10 6.1 2.1 2.6 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 bZIP_1 PF00170.16 ETO03498.1 - 6.1 6.8 15.9 4.8 7.2 2.6 3.4 2 2 1 3 3 3 0 bZIP transcription factor DUF1319 PF07028.6 ETO03498.1 - 7.9 6.6 10.3 4.7 7.4 3.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1319) TLD PF07534.11 ETO03499.1 - 6.2e-10 39.2 0.0 1.8e-09 37.6 0.0 1.9 1 0 0 1 1 1 1 TLD COG5 PF10392.4 ETO03499.1 - 3.4 7.6 9.5 8 6.4 3.8 2.6 2 1 1 3 3 3 0 Golgi transport complex subunit 5 Spo0A_C PF08769.6 ETO03500.1 - 0.13 12.1 4.2 2.7 7.9 2.9 2.7 1 1 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal DUF948 PF06103.6 ETO03500.1 - 9.4 6.1 10.8 1.9 8.3 1.4 3.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TPR_12 PF13424.1 ETO03501.1 - 1.3e-67 223.7 22.0 1.2e-22 79.6 0.5 2.4 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO03501.1 - 4.4e-32 109.0 0.0 6.6e-09 35.4 0.0 4.0 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO03501.1 - 2e-28 96.7 22.4 1.9e-09 36.7 0.6 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO03501.1 - 2.5e-27 94.3 22.0 8.1e-15 54.2 3.3 2.9 1 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 ETO03501.1 - 2.6e-23 79.9 17.0 4.3e-07 29.3 0.4 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO03501.1 - 4.3e-22 76.1 24.3 3.4e-07 29.5 0.5 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO03501.1 - 1.3e-21 74.6 3.2 4.7e-06 25.9 0.0 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO03501.1 - 3.6e-12 45.7 0.0 0.076 13.6 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO03501.1 - 4.4e-12 45.0 0.6 0.0011 18.2 0.0 4.2 4 0 0 4 4 4 3 SHNi-TPR TPR_16 PF13432.1 ETO03501.1 - 1.4e-11 44.7 0.0 0.0001 22.8 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO03501.1 - 2.8e-11 43.0 2.2 0.028 14.8 0.0 4.5 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO03501.1 - 2.4e-08 33.5 13.0 0.037 14.2 0.1 4.7 3 3 0 3 3 3 3 Tetratricopeptide repeat SNAP PF14938.1 ETO03501.1 - 9.5e-07 28.2 2.7 2.8e-06 26.7 1.9 1.7 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP Apc3 PF12895.2 ETO03501.1 - 1.1e-06 28.6 10.5 3.9e-06 26.9 4.6 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO03501.1 - 7.7e-06 26.1 1.0 0.0024 18.1 0.4 2.5 1 1 2 3 3 3 3 Tetratricopeptide repeat DUF627 PF04781.7 ETO03501.1 - 2.3e-05 23.9 6.1 0.67 9.5 0.9 3.6 2 2 1 3 3 3 2 Protein of unknown function (DUF627) MIT PF04212.13 ETO03501.1 - 0.00011 22.0 6.8 1 9.2 0.1 3.9 3 1 1 4 4 4 2 MIT (microtubule interacting and transport) domain DUF2225 PF09986.4 ETO03501.1 - 0.0016 17.9 5.7 0.0099 15.3 0.3 2.2 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_3 PF07720.7 ETO03501.1 - 0.0017 18.0 0.8 0.0017 18.0 0.6 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat Sel1 PF08238.7 ETO03501.1 - 0.01 16.4 7.9 6.3 7.5 0.1 3.8 4 1 0 4 4 4 0 Sel1 repeat ATP-synt_E_2 PF08112.6 ETO03501.1 - 0.012 15.6 4.1 6.2 6.9 0.1 3.8 4 0 0 4 4 4 0 ATP synthase epsilon subunit NSF PF02071.15 ETO03501.1 - 0.024 15.0 2.2 35 5.6 0.0 3.8 3 0 0 3 3 3 0 Aromatic-di-Alanine (AdAR) repeat DUF1120 PF06551.7 ETO03501.1 - 0.073 13.3 0.0 48 4.2 0.0 3.0 1 1 3 4 4 4 0 Protein of unknown function (DUF1120) TPR_20 PF14561.1 ETO03501.1 - 0.08 13.0 0.3 1.2 9.2 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat SPO22 PF08631.5 ETO03501.1 - 0.17 10.9 1.6 2.1 7.3 0.0 2.8 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like PPR PF01535.15 ETO03501.1 - 0.46 10.5 3.1 24 5.2 0.0 4.2 5 1 0 5 5 4 0 PPR repeat OEP PF02321.13 ETO03501.1 - 0.47 10.0 5.9 7.7 6.0 1.4 2.7 1 1 2 3 3 3 0 Outer membrane efflux protein UVR PF02151.14 ETO03501.1 - 2.2 7.9 10.4 1.9 8.1 0.1 3.9 4 0 0 4 4 4 0 UvrB/uvrC motif Calci_bind_CcbP PF11535.3 ETO03503.1 - 0.31 11.3 0.2 0.31 11.3 0.1 2.2 2 1 0 2 2 2 0 Calcium binding Allexi_40kDa PF05549.6 ETO03503.1 - 6.4 5.9 6.5 22 4.2 0.0 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein ARS2 PF04959.8 ETO03504.1 - 0.0018 18.5 0.2 0.0042 17.3 0.1 1.5 1 0 0 1 1 1 1 Arsenite-resistance protein 2 TraV PF09676.5 ETO03506.1 - 0.042 14.5 2.3 0.056 14.1 1.6 1.3 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) DUF1302 PF06980.6 ETO03506.1 - 0.075 11.5 1.7 0.095 11.2 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1302) Atrophin-1 PF03154.10 ETO03506.1 - 0.93 7.5 12.6 1.1 7.3 8.8 1.0 1 0 0 1 1 1 0 Atrophin-1 family DUF1510 PF07423.6 ETO03506.1 - 1.3 8.3 18.8 0.48 9.7 11.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Vfa1 PF08432.5 ETO03506.1 - 1.5 8.8 21.5 0.18 11.8 11.8 1.8 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Neur_chan_memb PF02932.11 ETO03506.1 - 1.5 8.6 4.8 1.6 8.5 3.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1754 PF08555.5 ETO03506.1 - 2 9.0 31.8 0.26 11.9 18.5 2.0 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) POX PF07526.6 ETO03506.1 - 2.4 8.3 11.6 0.56 10.4 6.0 1.6 2 0 0 2 2 2 0 Associated with HOX DUF2413 PF10310.4 ETO03506.1 - 2.7 6.7 15.9 4 6.1 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Pox_Ag35 PF03286.9 ETO03506.1 - 3.7 7.0 20.5 0.19 11.2 10.8 1.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein SR-25 PF10500.4 ETO03506.1 - 5.1 6.4 22.3 0.064 12.7 10.5 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Paramyxo_ncap PF00973.14 ETO03506.1 - 5.3 5.6 7.9 6 5.4 5.5 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CobT PF06213.7 ETO03506.1 - 6.8 5.7 11.9 12 4.9 8.3 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Atrophin-1 PF03154.10 ETO03507.1 - 0.066 11.3 19.4 0.083 11.0 13.4 1.1 1 0 0 1 1 1 0 Atrophin-1 family NARP1 PF12569.3 ETO03507.1 - 0.62 8.7 31.1 0.79 8.4 21.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Draxin PF15550.1 ETO03507.1 - 7.5 6.1 21.6 9 5.8 14.9 1.0 1 0 0 1 1 1 0 Draxin Daxx PF03344.10 ETO03507.1 - 9.3 4.5 31.2 10 4.4 21.6 1.0 1 0 0 1 1 1 0 Daxx Family DUF3776 PF12618.3 ETO03508.1 - 0.083 13.4 2.9 10 6.7 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3776) HNF_C PF09354.5 ETO03509.1 - 0.023 15.8 0.3 0.023 15.8 0.2 2.0 3 0 0 3 3 3 0 HNF3 C-terminal domain BLVR PF06375.6 ETO03509.1 - 2.4 7.9 5.1 2.9 7.7 3.5 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) M_domain PF12938.2 ETO03510.1 - 4.2 7.1 10.3 5.8 6.6 7.1 1.1 1 0 0 1 1 1 0 M domain of GW182 DUF3754 PF12576.3 ETO03511.1 - 0.018 14.6 0.2 0.19 11.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) DUF1371 PF07115.6 ETO03514.1 - 0.054 13.6 0.1 0.077 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1371) Tubulin PF00091.20 ETO03515.1 - 5.8e-32 111.2 0.1 7.9e-32 110.8 0.1 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO03515.1 - 0.00054 19.9 0.1 0.0011 19.0 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.1 ETO03515.1 - 0.18 10.7 0.6 0.29 10.0 0.4 1.4 1 1 1 2 2 2 0 Tubulin like DUF2893 PF11459.3 ETO03516.1 - 0.029 14.1 0.1 0.081 12.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknwon function (DUF2893) Kelch_6 PF13964.1 ETO03517.1 - 0.00099 19.1 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 Kelch motif Kelch_2 PF07646.10 ETO03517.1 - 0.001 18.7 0.4 0.0021 17.7 0.2 1.6 1 0 0 1 1 1 1 Kelch motif Kelch_4 PF13418.1 ETO03517.1 - 0.0027 17.4 0.5 0.0082 15.8 0.2 1.9 1 1 1 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO03517.1 - 0.0051 16.3 0.5 0.0099 15.4 0.2 1.6 1 1 0 1 1 1 1 Kelch motif Kelch_3 PF13415.1 ETO03517.1 - 0.048 13.8 0.0 0.42 10.8 0.0 2.2 2 0 0 2 2 2 0 Galactose oxidase, central domain ERAP1_C PF11838.3 ETO03520.1 - 4.3e-07 29.4 0.0 5.8e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain TAF4 PF05236.9 ETO03520.1 - 0.11 11.7 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family HEAT PF02985.17 ETO03522.1 - 2.7e-14 51.8 0.0 0.0016 18.3 0.0 3.5 3 0 0 3 3 3 3 HEAT repeat HEAT_2 PF13646.1 ETO03522.1 - 1.7e-12 47.4 0.1 1.3e-06 28.5 0.0 2.3 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 ETO03522.1 - 3.3e-09 36.9 0.0 0.0002 21.7 0.0 2.3 1 1 1 2 2 2 2 HEAT-like repeat HEAT_PBS PF03130.11 ETO03522.1 - 1.1e-05 25.3 0.0 0.11 13.0 0.0 3.8 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 ETO03522.1 - 0.00051 18.4 2.0 0.00061 18.1 1.4 1.0 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit CLASP_N PF12348.3 ETO03522.1 - 0.0031 16.9 0.7 0.035 13.4 0.2 2.2 2 1 0 2 2 2 1 CLASP N terminal DUF3554 PF12074.3 ETO03522.1 - 0.0038 16.6 0.6 0.044 13.1 0.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF3554) KAP PF05804.7 ETO03522.1 - 0.0068 14.3 0.9 0.15 9.9 0.0 2.5 1 1 2 3 3 3 1 Kinesin-associated protein (KAP) DUF3385 PF11865.3 ETO03522.1 - 0.013 15.4 0.7 0.33 10.8 0.5 3.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.2 ETO03522.1 - 0.016 15.5 0.1 1.8 8.9 0.0 2.4 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region 14-3-3 PF00244.15 ETO03522.1 - 0.051 12.6 4.8 0.76 8.8 0.5 2.2 1 1 1 2 2 2 0 14-3-3 protein IFRD PF05004.8 ETO03522.1 - 0.056 12.5 1.9 0.13 11.3 0.3 2.0 1 1 1 2 2 2 0 Interferon-related developmental regulator (IFRD) Activator-TraM PF11657.3 ETO03522.1 - 0.12 11.8 2.5 0.45 9.9 0.1 2.1 1 1 0 2 2 2 0 Transcriptional activator TraM FPL PF09758.4 ETO03522.1 - 0.4 10.4 4.1 5.1 6.8 1.3 2.8 1 1 1 2 2 2 0 Uncharacterised conserved protein DUF2207 PF09972.4 ETO03523.1 - 0.00021 20.0 1.0 0.00023 19.8 0.7 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF1218 PF06749.7 ETO03523.1 - 0.1 13.0 0.2 0.15 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1218) Agouti PF05039.7 ETO03523.1 - 1.5 9.2 6.4 2.8 8.3 4.4 1.5 1 0 0 1 1 1 0 Agouti protein TPR_12 PF13424.1 ETO03527.1 - 2.7e-56 187.4 23.8 6.8e-24 83.6 2.4 2.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO03527.1 - 1.8e-32 109.5 31.6 3.3e-11 42.3 1.9 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO03527.1 - 2.8e-30 103.7 35.1 3.4e-15 55.4 5.3 2.8 1 1 2 3 3 3 3 TPR repeat TPR_10 PF13374.1 ETO03527.1 - 5.3e-25 86.5 0.2 7.5e-08 32.0 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO03527.1 - 7.4e-25 84.8 21.4 9.9e-09 34.4 1.7 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO03527.1 - 1.1e-22 77.9 33.4 3.4e-08 32.7 1.9 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO03527.1 - 7.9e-21 72.1 8.9 1e-05 24.9 0.0 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO03527.1 - 5e-18 65.2 4.8 1.8e-08 34.8 0.0 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO03527.1 - 8.3e-16 57.2 6.1 0.001 19.3 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO03527.1 - 3e-14 52.2 0.0 0.0041 17.6 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO03527.1 - 6.6e-11 41.5 22.8 0.0016 18.4 1.9 4.7 4 2 0 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 ETO03527.1 - 1.5e-10 41.0 18.5 1.7e-07 31.2 5.9 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO03527.1 - 7.1e-09 35.8 4.8 0.00079 19.7 0.7 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat SNAP PF14938.1 ETO03527.1 - 1.1e-08 34.6 21.5 1.6e-05 24.2 4.3 2.3 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP MIT PF04212.13 ETO03527.1 - 5.9e-08 32.4 14.9 0.061 13.2 0.3 4.2 4 0 0 4 4 4 3 MIT (microtubule interacting and transport) domain Sel1 PF08238.7 ETO03527.1 - 2.6e-07 31.0 8.5 0.25 12.0 0.2 4.1 4 0 0 4 4 4 3 Sel1 repeat SHNi-TPR PF10516.4 ETO03527.1 - 7.9e-07 28.2 2.9 0.3 10.3 0.1 3.9 4 0 0 4 4 4 2 SHNi-TPR DUF2225 PF09986.4 ETO03527.1 - 1.9e-05 24.2 6.6 0.0032 16.9 1.0 2.1 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_5 PF12688.2 ETO03527.1 - 0.00032 20.7 1.3 0.2 11.6 0.0 3.6 1 1 2 4 4 4 1 Tetratrico peptide repeat PPR PF01535.15 ETO03527.1 - 0.0004 20.1 1.7 0.77 9.8 0.2 3.4 3 0 0 3 3 3 1 PPR repeat DUF627 PF04781.7 ETO03527.1 - 0.0018 17.8 4.6 1.1 8.8 0.1 3.1 1 1 2 3 3 3 1 Protein of unknown function (DUF627) RPN7 PF10602.4 ETO03527.1 - 0.0033 16.8 6.5 0.011 15.0 3.9 2.1 1 1 0 1 1 1 1 26S proteasome subunit RPN7 TPR_3 PF07720.7 ETO03527.1 - 0.0057 16.4 20.7 0.011 15.5 1.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat Foie-gras_1 PF11817.3 ETO03527.1 - 0.014 14.8 1.5 2.8 7.3 0.1 2.9 3 0 0 3 3 3 0 Foie gras liver health family 1 BRO1 PF03097.13 ETO03527.1 - 0.034 12.9 4.0 0.096 11.4 2.8 1.7 1 1 0 1 1 1 0 BRO1-like domain Mob_Pre PF01076.14 ETO03527.1 - 0.041 13.5 0.5 0.041 13.5 0.3 2.1 1 1 1 2 2 2 0 Plasmid recombination enzyme NRDE-2 PF08424.5 ETO03527.1 - 0.14 11.0 0.2 0.4 9.5 0.1 1.6 1 1 1 2 2 2 0 NRDE-2, necessary for RNA interference NSF PF02071.15 ETO03527.1 - 0.16 12.6 14.2 11 7.0 0.1 5.3 5 0 0 5 5 4 0 Aromatic-di-Alanine (AdAR) repeat Sda PF08970.5 ETO03527.1 - 0.24 10.9 2.9 4.4 6.8 0.1 3.4 3 1 0 3 3 3 0 Sporulation inhibitor A SPO22 PF08631.5 ETO03527.1 - 0.27 10.2 7.2 0.4 9.7 0.8 2.7 2 2 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like Prefoldin PF02996.12 ETO03527.1 - 0.28 10.8 4.4 1.5 8.4 0.4 3.0 2 1 1 3 3 3 0 Prefoldin subunit Ubiq-assoc PF09145.5 ETO03527.1 - 4.2 7.3 21.2 4.8 7.1 0.2 5.7 4 3 2 6 6 6 0 Ubiquitin-associated EMP70 PF02990.11 ETO03528.1 - 4.9e-71 239.7 16.3 4.3e-68 230.0 11.3 2.0 1 1 0 1 1 1 1 Endomembrane protein 70 DUF1129 PF06570.6 ETO03528.1 - 0.39 9.9 7.6 0.57 9.4 3.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF3353 PF11833.3 ETO03528.1 - 0.45 9.9 2.3 0.7 9.3 1.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3353) Chs3p PF12271.3 ETO03528.1 - 7 5.5 12.9 1.4 7.8 5.2 2.0 2 0 0 2 2 2 0 Chitin synthase III catalytic subunit Sec6 PF06046.8 ETO03529.1 - 1.7e-41 141.9 20.9 2.3e-41 141.5 14.5 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec6 DUF445 PF04286.7 ETO03529.1 - 0.0018 17.8 9.5 0.099 12.1 0.1 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF445) SopA PF13981.1 ETO03529.1 - 0.14 12.1 0.2 0.14 12.1 0.1 4.1 3 2 1 4 4 4 0 SopA-like central domain CAS_CSE1 PF03378.10 ETO03530.1 - 0.0086 14.4 0.1 0.01 14.1 0.1 1.1 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus FNIP_M PF14637.1 ETO03530.1 - 0.13 11.7 1.8 0.2 11.2 1.3 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain Peptidase_M3 PF01432.15 ETO03531.1 - 1.7e-21 76.8 0.6 3e-21 76.0 0.4 1.4 1 1 0 1 1 1 1 Peptidase family M3 DUF464 PF04327.7 ETO03531.1 - 0.096 12.9 0.2 0.22 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF464) zf-RVT PF13966.1 ETO03532.1 - 0.015 15.6 0.1 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase WD40 PF00400.27 ETO03533.1 - 2.1e-13 49.6 8.5 2.4e-09 36.7 0.2 2.8 3 1 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO03533.1 - 0.0002 19.6 0.1 0.15 10.1 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Pico_P2A PF00947.14 ETO03533.1 - 0.042 13.6 0.0 0.058 13.1 0.0 1.2 1 0 0 1 1 1 0 Picornavirus core protein 2A Nucleoporin_N PF08801.6 ETO03533.1 - 0.043 12.5 0.1 0.1 11.3 0.0 1.6 1 1 1 2 2 2 0 Nup133 N terminal like Mss4 PF04421.8 ETO03533.1 - 0.054 13.3 0.2 0.095 12.5 0.0 1.6 2 0 0 2 2 2 0 Mss4 protein Ricin_B_lectin PF00652.17 ETO03533.1 - 0.066 13.2 1.3 0.15 12.1 0.6 1.7 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain DUF551 PF04448.7 ETO03535.1 - 0.07 13.8 0.4 0.16 12.7 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF551) HEAT_2 PF13646.1 ETO03536.1 - 5e-30 103.6 0.1 1.4e-08 34.9 0.0 6.3 1 1 4 6 6 6 5 HEAT repeats HEAT PF02985.17 ETO03536.1 - 3.1e-21 73.4 0.0 0.0024 17.7 0.0 8.2 9 0 0 9 9 8 5 HEAT repeat HEAT_EZ PF13513.1 ETO03536.1 - 1.3e-19 70.0 0.0 0.0044 17.4 0.0 7.9 5 3 5 10 10 10 5 HEAT-like repeat Cnd1 PF12717.2 ETO03536.1 - 3.3e-11 43.3 13.2 0.0022 17.8 0.1 5.2 1 1 3 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 ETO03536.1 - 3.2e-08 33.8 4.4 0.07 13.5 0.0 5.5 2 2 6 8 8 8 4 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 ETO03536.1 - 2.2e-07 30.4 6.2 0.0023 17.3 0.3 3.9 2 1 2 4 4 4 3 CLASP N terminal NLE PF08154.7 ETO03536.1 - 9.3e-06 25.5 6.9 8 6.5 0.0 6.8 7 0 0 7 7 6 1 NLE (NUC135) domain DUF3596 PF12167.3 ETO03536.1 - 2.7e-05 23.6 0.1 7.5 6.1 0.0 5.7 6 0 0 6 6 6 1 Domain of unknown function (DUF3596) HEAT_PBS PF03130.11 ETO03536.1 - 9.9e-05 22.4 0.0 65 4.4 0.0 5.8 6 0 0 6 6 5 0 PBS lyase HEAT-like repeat DUF2435 PF10363.4 ETO03536.1 - 0.0004 20.2 7.3 1.1 9.1 0.1 5.6 4 1 5 9 9 7 3 Protein of unknown function (DUF2435) Ribosomal_S3Ae PF01015.13 ETO03536.1 - 0.0013 18.0 8.0 1.2 8.4 0.0 5.3 2 1 4 6 6 6 1 Ribosomal S3Ae family DUF3782 PF12644.2 ETO03536.1 - 0.0051 16.5 0.2 1.3 8.9 0.0 4.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3782) DUF3554 PF12074.3 ETO03536.1 - 0.0062 16.0 11.7 0.5 9.7 0.0 4.9 1 1 3 4 4 4 3 Domain of unknown function (DUF3554) ENTH PF01417.15 ETO03536.1 - 0.15 11.8 10.8 11 5.8 0.0 5.3 3 2 3 6 6 6 0 ENTH domain ETC_C1_NDUFA5 PF04716.9 ETO03536.1 - 0.32 10.5 4.5 21 4.7 0.1 4.0 3 0 0 3 3 3 0 ETC complex I subunit conserved region DUF3349 PF11829.3 ETO03536.1 - 1.7 9.0 7.7 13 6.2 0.1 5.2 3 1 3 7 7 6 0 Protein of unknown function (DUF3349) FAM209 PF15206.1 ETO03538.1 - 0.057 13.2 0.2 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 FAM209 family BAR_3_WASP_bdg PF10456.4 ETO03541.1 - 0.0062 15.8 7.1 0.0088 15.3 0.3 2.6 2 1 1 3 3 3 1 WASP-binding domain of Sorting nexin protein NAAA-beta PF15508.1 ETO03541.1 - 0.014 15.7 2.0 0.82 10.0 0.1 3.6 2 1 2 4 4 4 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase TBCA PF02970.11 ETO03541.1 - 0.047 13.7 0.4 0.64 10.1 0.0 2.8 2 1 1 3 3 3 0 Tubulin binding cofactor A HrpF PF06266.7 ETO03541.1 - 0.056 13.5 0.1 1.5 9.0 0.0 2.6 2 0 0 2 2 2 0 HrpF protein Tox-MPTase4 PF15640.1 ETO03541.1 - 0.19 11.3 4.9 1.5 8.4 0.0 3.1 3 0 0 3 3 3 0 Metallopeptidase toxin 4 CABIT PF12736.2 ETO03542.1 - 0.044 12.7 0.0 0.046 12.7 0.0 1.2 1 0 0 1 1 1 0 Cell-cycle sustaining, positive selection, EzrA PF06160.7 ETO03543.1 - 0.046 11.9 0.7 0.051 11.7 0.5 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF1708 PF08101.6 ETO03543.1 - 0.07 11.9 0.1 0.094 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) ChAPs PF09295.5 ETO03545.1 - 0.01 14.6 1.6 0.012 14.4 1.1 1.2 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) DNA_ligase_A_N PF04675.9 ETO03545.1 - 0.01 15.6 0.1 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 DNA ligase N terminus PNMA PF14893.1 ETO03545.1 - 0.088 11.8 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 PNMA Fer2_4 PF13510.1 ETO03546.1 - 0.023 14.5 0.0 0.03 14.1 0.0 1.1 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain SieB PF14163.1 ETO03546.1 - 0.088 12.3 1.4 0.15 11.6 1.0 1.3 1 0 0 1 1 1 0 Superinfection exclusion protein B WD40 PF00400.27 ETO03547.1 - 1.2e-69 227.9 23.1 1e-12 47.3 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO03547.1 - 2.8e-11 42.2 3.8 0.016 13.3 0.0 6.0 2 1 2 5 5 5 5 Nucleoporin Nup120/160 IncA PF04156.9 ETO03547.1 - 0.037 13.6 24.3 0.028 14.0 9.9 2.3 2 0 0 2 2 2 0 IncA protein DUF1664 PF07889.7 ETO03547.1 - 0.39 10.5 15.2 0.14 11.9 2.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PigN PF04987.9 ETO03547.1 - 0.62 8.6 1.9 1 7.9 1.3 1.2 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) Methyltransf_12 PF08242.7 ETO03547.1 - 1.1 9.7 3.6 1.7 9.1 0.3 2.7 2 0 0 2 2 2 0 Methyltransferase domain PPR_2 PF13041.1 ETO03548.1 - 5.4e-05 23.0 0.7 0.1 12.5 0.1 2.4 2 0 0 2 2 2 2 PPR repeat family PPR PF01535.15 ETO03548.1 - 0.0013 18.5 0.1 2.1 8.4 0.0 2.5 2 0 0 2 2 2 2 PPR repeat Vasohibin PF14822.1 ETO03549.1 - 0.0089 15.1 0.7 0.0097 15.0 0.5 1.0 1 0 0 1 1 1 1 Vasohibin ADIP PF11559.3 ETO03549.1 - 0.044 13.6 3.2 0.053 13.4 2.2 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding ASFV_p27 PF06556.6 ETO03552.1 - 0.016 15.0 0.7 0.037 13.9 0.0 1.7 2 0 0 2 2 2 0 IAP-like protein p27 C-terminus PPR_2 PF13041.1 ETO03553.1 - 0.027 14.4 0.1 0.072 13.0 0.1 1.7 1 0 0 1 1 1 0 PPR repeat family Peptidase_C80 PF11713.3 ETO03553.1 - 0.11 12.2 0.1 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase C80 family PPR PF01535.15 ETO03553.1 - 0.17 11.9 1.7 0.21 11.6 0.0 2.1 3 0 0 3 3 3 0 PPR repeat WD40 PF00400.27 ETO03554.1 - 0.00028 20.6 3.1 0.0011 18.7 1.1 2.4 2 1 0 2 2 2 1 WD domain, G-beta repeat NusB PF01029.13 ETO03555.1 - 0.051 13.5 1.4 0.18 11.8 1.0 1.7 1 1 0 1 1 1 0 NusB family DUF588 PF04535.7 ETO03556.1 - 0.0093 15.5 0.0 0.013 15.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF588) GCN5L1 PF06320.8 ETO03556.1 - 0.084 12.7 0.4 0.12 12.2 0.3 1.3 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) Mannitol_dh PF01232.18 ETO03557.1 - 0.005 16.7 0.6 0.0087 16.0 0.2 1.5 1 1 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain Mem_trans PF03547.13 ETO03557.1 - 4.9 5.3 11.4 0.055 11.7 2.0 1.7 1 1 1 2 2 2 0 Membrane transport protein DUF1207 PF06727.6 ETO03559.1 - 0.025 13.4 0.1 0.029 13.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1207) DUF3452 PF11934.3 ETO03559.1 - 0.11 11.8 3.4 0.17 11.1 1.9 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3452) DUF1283 PF06932.6 ETO03559.1 - 0.17 11.8 3.6 0.32 11.0 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1283) HEAT_2 PF13646.1 ETO03560.1 - 4.1e-22 78.2 0.0 3e-07 30.6 0.0 8.1 5 2 3 8 8 8 4 HEAT repeats HEAT PF02985.17 ETO03560.1 - 1.1e-18 65.5 0.4 1.9 8.7 0.0 11.8 12 0 0 12 12 12 4 HEAT repeat HEAT_EZ PF13513.1 ETO03560.1 - 2.3e-09 37.4 0.0 0.077 13.5 0.0 8.2 7 3 3 10 10 10 2 HEAT-like repeat Ank_4 PF13637.1 ETO03560.1 - 0.00088 19.7 0.1 0.0049 17.3 0.1 2.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO03560.1 - 0.0048 17.1 0.0 0.019 15.2 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Inhibitor_I9 PF05922.11 ETO03560.1 - 0.013 16.0 2.0 70 4.0 0.0 5.3 5 0 0 5 5 5 0 Peptidase inhibitor I9 Ank_3 PF13606.1 ETO03560.1 - 0.018 15.2 0.0 0.15 12.4 0.0 2.8 1 0 0 1 1 1 0 Ankyrin repeat DUF2435 PF10363.4 ETO03560.1 - 0.14 12.0 29.6 0.51 10.2 0.2 8.4 7 2 1 9 9 9 0 Protein of unknown function (DUF2435) Vac14_Fab1_bd PF12755.2 ETO03560.1 - 3 8.2 29.0 0.12 12.7 0.1 8.2 7 3 2 10 10 10 0 Vacuolar 14 Fab1-binding region Kinetochor_Ybp2 PF08568.5 ETO03561.1 - 0.013 13.7 0.3 0.014 13.6 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin Tubulin PF00091.20 ETO03563.1 - 4.1e-27 95.4 0.0 8e-27 94.4 0.0 1.4 1 1 1 2 2 2 1 Tubulin/FtsZ family, GTPase domain Lipase_3 PF01764.20 ETO03563.1 - 0.0023 17.5 0.0 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 ETO03563.1 - 0.06 13.1 0.0 0.06 13.1 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family WD40 PF00400.27 ETO03564.1 - 2.3e-46 154.0 14.8 2e-11 43.3 0.6 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat Pentapeptide PF00805.17 ETO03564.1 - 1.1e-06 27.6 0.2 2.2e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO03564.1 - 7.8e-06 25.6 0.4 1.9e-05 24.3 0.2 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Nup160 PF11715.3 ETO03564.1 - 3.2e-05 22.2 2.8 0.032 12.3 0.2 2.5 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Pentapeptide_3 PF13576.1 ETO03564.1 - 0.00012 21.9 1.8 0.00044 20.0 1.2 2.0 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Cytochrom_D1 PF02239.11 ETO03564.1 - 0.015 13.5 0.7 0.038 12.2 0.3 1.7 1 1 0 1 1 1 0 Cytochrome D1 heme domain PD40 PF07676.7 ETO03564.1 - 0.059 13.0 6.6 1.6 8.4 0.0 3.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Crust_neurohorm PF01147.12 ETO03565.1 - 0.0034 16.6 0.1 0.0051 16.0 0.1 1.4 1 0 0 1 1 1 1 Crustacean CHH/MIH/GIH neurohormone family WbqC PF08889.6 ETO03565.1 - 0.015 14.7 0.2 0.02 14.3 0.1 1.2 1 0 0 1 1 1 0 WbqC-like protein family Ribosomal_L36 PF00444.13 ETO03565.1 - 0.018 14.9 0.1 0.037 14.0 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L36 TypeIII_RM_meth PF12564.3 ETO03565.1 - 0.44 10.5 2.8 1.4 8.9 0.3 2.2 2 0 0 2 2 2 0 Type III restriction/modification enzyme methylation subunit WD40 PF00400.27 ETO03566.1 - 5.9e-24 83.0 11.0 1.6e-10 40.4 0.1 4.5 4 1 0 4 4 4 3 WD domain, G-beta repeat zf-TRAF PF02176.13 ETO03566.1 - 6.8e-06 26.3 3.2 3.4e-05 24.1 2.2 2.3 1 0 0 1 1 1 1 TRAF-type zinc finger EST1 PF10374.4 ETO03567.1 - 0.081 12.9 8.2 0.096 12.6 4.9 1.7 1 1 0 1 1 1 0 Telomerase activating protein Est1 UCH PF00443.24 ETO03568.1 - 2.2e-05 23.7 1.0 9.3e-05 21.6 0.1 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MOSC PF03473.12 ETO03568.1 - 0.053 12.9 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 MOSC domain TPR_12 PF13424.1 ETO03569.1 - 1.4e-126 412.6 12.6 5e-25 87.2 0.0 5.3 2 2 4 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.1 ETO03569.1 - 1.8e-64 212.0 0.0 3.8e-09 36.1 0.0 8.0 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_11 PF13414.1 ETO03569.1 - 1.7e-56 187.7 18.9 2.5e-15 55.8 0.1 5.1 4 1 1 5 5 5 5 TPR repeat TPR_7 PF13176.1 ETO03569.1 - 4.4e-54 176.0 8.0 2.5e-08 33.1 0.0 8.1 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_1 PF00515.23 ETO03569.1 - 5.9e-52 171.2 47.9 9.9e-09 34.4 0.3 8.2 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_2 PF07719.12 ETO03569.1 - 4.1e-38 126.2 36.0 9.6e-06 25.1 0.1 8.2 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.1 ETO03569.1 - 9.7e-37 122.0 60.9 1.3e-06 27.7 1.5 8.1 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_17 PF13431.1 ETO03569.1 - 1.7e-30 102.6 15.9 0.00069 19.6 0.0 9.4 7 2 1 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 ETO03569.1 - 2.6e-19 69.3 0.0 0.0063 17.1 0.0 6.0 1 1 6 7 7 7 7 Tetratricopeptide repeat Apc3 PF12895.2 ETO03569.1 - 2.4e-17 62.8 12.5 6e-06 26.3 0.4 5.0 1 1 3 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 ETO03569.1 - 6.5e-15 54.2 0.0 0.57 10.9 0.0 7.3 3 2 4 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO03569.1 - 9.6e-15 54.6 0.2 0.11 12.8 0.1 5.7 1 1 6 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.1 ETO03569.1 - 8.6e-13 47.8 6.0 0.6 10.7 0.0 7.6 7 0 0 7 7 7 2 Tetratricopeptide repeat MIT PF04212.13 ETO03569.1 - 2.2e-09 37.0 29.6 0.0044 16.8 0.1 7.4 8 0 0 8 8 8 3 MIT (microtubule interacting and transport) domain SNAP PF14938.1 ETO03569.1 - 2.3e-08 33.5 9.3 0.0031 16.7 0.4 4.0 1 1 1 3 3 3 3 Soluble NSF attachment protein, SNAP DUF627 PF04781.7 ETO03569.1 - 3.3e-06 26.6 8.7 4.6 6.9 0.0 6.7 1 1 6 7 7 7 1 Protein of unknown function (DUF627) SHNi-TPR PF10516.4 ETO03569.1 - 7.3e-05 21.9 4.8 25 4.2 0.0 6.8 7 0 0 7 7 7 0 SHNi-TPR TPR_3 PF07720.7 ETO03569.1 - 0.00011 21.8 41.3 0.0067 16.2 0.7 7.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_5 PF12688.2 ETO03569.1 - 0.00024 21.1 0.2 0.57 10.2 0.0 3.8 2 1 2 4 4 4 1 Tetratrico peptide repeat DUF3568 PF12092.3 ETO03569.1 - 0.00074 19.2 0.1 24 4.6 0.0 5.1 1 1 4 6 6 6 0 Protein of unknown function (DUF3568) PPR PF01535.15 ETO03569.1 - 0.0009 19.0 14.7 3.1 7.9 0.1 6.8 7 0 0 7 7 7 1 PPR repeat TPR_9 PF13371.1 ETO03569.1 - 0.0011 18.7 0.0 3.4 7.6 0.0 3.8 1 1 3 5 5 5 1 Tetratricopeptide repeat DUF2225 PF09986.4 ETO03569.1 - 0.0036 16.7 8.9 1.2 8.4 0.1 3.8 1 1 1 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) EzrA PF06160.7 ETO03569.1 - 0.0043 15.2 3.9 5.6 5.0 0.0 4.9 5 1 1 6 6 6 0 Septation ring formation regulator, EzrA ApoLp-III PF07464.6 ETO03569.1 - 0.021 14.8 0.1 1.7e+02 2.1 0.0 5.0 3 3 3 6 6 5 0 Apolipophorin-III precursor (apoLp-III) Sipho_tail PF05709.6 ETO03569.1 - 0.03 13.4 0.2 3.5 6.6 0.0 2.9 2 2 2 4 4 4 0 Phage tail protein Sel1 PF08238.7 ETO03569.1 - 0.034 14.8 18.8 2.2 9.0 0.0 6.9 8 0 0 8 8 6 0 Sel1 repeat NdhO PF11910.3 ETO03569.1 - 0.057 13.0 9.2 4.7 6.9 0.1 4.6 3 1 2 5 5 5 0 Cyanobacterial and plant NDH-1 subunit O Triabin PF03973.8 ETO03569.1 - 0.13 11.9 2.2 0.46 10.1 0.1 2.7 1 1 1 3 3 3 0 Triabin Fis1_TPR_C PF14853.1 ETO03569.1 - 2.2 8.2 24.0 20 5.1 0.1 7.2 8 0 0 8 8 7 0 Fis1 C-terminal tetratricopeptide repeat DUF1936 PF09151.5 ETO03569.1 - 8.8 5.9 11.7 1.1e+02 2.3 0.1 5.3 5 0 0 5 5 5 0 Domain of unknown function (DUF1936) RVP PF00077.15 ETO03570.1 - 0.022 14.6 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF4272 PF14094.1 ETO03570.1 - 0.057 12.4 0.1 0.11 11.5 0.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4272) DUF3571 PF12095.3 ETO03570.1 - 0.068 13.4 0.2 0.17 12.0 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3571) PC4 PF02229.11 ETO03571.1 - 0.0033 16.5 0.5 0.0054 15.9 0.3 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) TGFb_propeptide PF00688.13 ETO03571.1 - 0.0097 15.2 0.3 0.011 15.0 0.2 1.2 1 0 0 1 1 1 1 TGF-beta propeptide DUF607 PF04678.8 ETO03571.1 - 0.02 14.8 0.4 0.021 14.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF607 DUF912 PF06024.7 ETO03571.1 - 0.02 14.9 1.9 0.028 14.4 1.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pinin_SDK_memA PF04696.8 ETO03571.1 - 0.064 12.8 6.1 0.073 12.6 4.2 1.1 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Vfa1 PF08432.5 ETO03571.1 - 0.17 11.8 5.3 0.19 11.7 3.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Ycf1 PF05758.7 ETO03571.1 - 0.22 9.1 5.4 0.22 9.2 3.7 1.0 1 0 0 1 1 1 0 Ycf1 CMV_1a PF12467.3 ETO03571.1 - 0.71 10.2 4.5 0.77 10.1 3.1 1.1 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family HSP90 PF00183.13 ETO03572.1 - 0.036 12.4 5.1 0.049 12.0 3.5 1.1 1 0 0 1 1 1 0 Hsp90 protein CDC45 PF02724.9 ETO03572.1 - 0.14 10.1 1.9 0.17 9.9 1.3 1.1 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.5 ETO03572.1 - 0.19 11.9 9.1 0.3 11.3 6.3 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain La PF05383.12 ETO03573.1 - 1.1e-12 47.5 0.0 1.9e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 La domain Packaging_FI PF14000.1 ETO03573.1 - 0.0025 17.9 0.1 0.0035 17.5 0.1 1.3 1 0 0 1 1 1 1 DNA packaging protein FI DASH_Spc34 PF08657.5 ETO03573.1 - 0.018 14.7 1.9 0.023 14.3 1.3 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 Syntaxin-6_N PF09177.6 ETO03573.1 - 0.025 14.9 0.3 0.054 13.8 0.2 1.6 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Striatin PF08232.7 ETO03573.1 - 0.063 13.5 1.0 0.09 13.0 0.7 1.3 1 0 0 1 1 1 0 Striatin family Fmp27_WPPW PF10359.4 ETO03573.1 - 0.14 10.5 1.3 0.14 10.5 0.9 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain CCDC92 PF14916.1 ETO03573.1 - 0.2 11.2 1.2 0.35 10.5 0.1 1.9 2 0 0 2 2 2 0 Coiled-coil domain of unknown function DUF2312 PF10073.4 ETO03573.1 - 0.29 10.5 2.6 0.23 10.8 0.4 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Syntaxin PF00804.20 ETO03573.1 - 0.93 9.6 4.8 0.21 11.7 0.9 1.7 2 0 0 2 2 2 0 Syntaxin Seryl_tRNA_N PF02403.17 ETO03573.1 - 1.1 9.3 4.7 0.6 10.1 1.8 1.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Nucleoporin2 PF04096.9 ETO03574.1 - 4.6e-30 104.2 0.0 7.8e-29 100.2 0.0 2.4 1 1 0 1 1 1 1 Nucleoporin autopeptidase Fumarate_red_C PF02300.12 ETO03575.1 - 0.025 14.4 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 Fumarate reductase subunit C TraH PF06122.6 ETO03576.1 - 0.16 10.7 5.5 0.2 10.4 3.4 1.4 1 1 0 1 1 1 0 Conjugative relaxosome accessory transposon protein EF-hand_6 PF13405.1 ETO03576.1 - 0.18 11.7 0.0 0.18 11.7 0.0 3.0 4 0 0 4 4 4 0 EF-hand domain Trypan_PARP PF05887.6 ETO03576.1 - 1.3 8.8 10.3 0.048 13.4 3.2 1.5 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) SDA1 PF05285.7 ETO03578.1 - 0.29 10.3 16.7 0.52 9.5 11.6 1.3 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.4 ETO03578.1 - 9 4.8 26.3 11 4.6 17.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2457) MMR_HSR1 PF01926.18 ETO03579.1 - 6.9e-07 29.2 0.0 2.6e-06 27.3 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 ETO03579.1 - 0.00044 19.0 10.2 0.00072 18.3 6.9 1.9 1 1 0 1 1 1 1 G-protein alpha subunit DUF258 PF03193.11 ETO03579.1 - 0.0016 17.6 1.3 0.02 14.1 0.9 2.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 ETO03579.1 - 0.0049 17.0 0.1 0.082 13.0 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 ETO03579.1 - 0.0052 16.7 0.0 0.019 14.9 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain T2SE PF00437.15 ETO03579.1 - 0.0057 15.6 0.1 0.0098 14.8 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.22 ETO03579.1 - 0.0057 16.9 1.0 0.02 15.2 0.2 2.4 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 ETO03579.1 - 0.0079 15.7 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain PduV-EutP PF10662.4 ETO03579.1 - 0.011 15.1 0.1 0.065 12.7 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 ETO03579.1 - 0.015 15.0 0.0 0.058 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) GTP_EFTU PF00009.22 ETO03579.1 - 0.019 14.3 0.1 0.079 12.3 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 ETO03579.1 - 0.026 13.9 0.2 0.048 13.1 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_17 PF13207.1 ETO03579.1 - 0.08 13.7 0.4 0.55 11.0 0.1 2.5 1 1 0 2 2 2 0 AAA domain DBI_PRT PF02277.12 ETO03579.1 - 0.23 10.5 0.0 0.42 9.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyltransferase Dynamin_N PF00350.18 ETO03579.1 - 0.4 10.4 10.9 0.41 10.4 5.7 2.4 2 1 0 2 2 2 0 Dynamin family PAXNEB PF05625.6 ETO03580.1 - 0.13 11.0 4.6 0.14 10.9 3.2 1.1 1 0 0 1 1 1 0 PAXNEB protein DUF3930 PF13067.1 ETO03580.1 - 0.14 12.0 1.0 0.94 9.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3930) HSA PF07529.8 ETO03580.1 - 0.3 10.9 11.3 0.053 13.3 4.4 2.1 2 0 0 2 2 2 0 HSA KOG2701 PF09762.4 ETO03580.1 - 0.3 11.1 5.3 2 8.4 3.9 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein (DUF2037) RNA_pol_Rpb1_5 PF04998.12 ETO03580.1 - 0.31 10.2 3.8 0.35 10.0 2.6 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Peptidase_U57 PF05582.7 ETO03580.1 - 0.35 9.8 4.1 0.43 9.5 2.9 1.1 1 0 0 1 1 1 0 YabG peptidase U57 DUF3987 PF13148.1 ETO03580.1 - 1.2 7.6 6.9 1.5 7.2 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) RNA_pol_Rbc25 PF08292.7 ETO03580.1 - 3.2 7.9 6.8 3.5 7.8 3.8 1.9 1 1 1 2 2 2 0 RNA polymerase III subunit Rpc25 DUF3915 PF13054.1 ETO03580.1 - 4 7.4 6.6 2.5 8.0 2.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3915) HEAT_2 PF13646.1 ETO03581.1 - 4.4e-17 62.1 0.0 2.1e-06 27.9 0.0 5.2 2 1 3 5 5 5 3 HEAT repeats HEAT PF02985.17 ETO03581.1 - 6.8e-15 53.7 0.1 0.00049 19.9 0.0 7.4 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.1 ETO03581.1 - 8.7e-11 41.9 0.0 0.00085 19.7 0.0 5.5 4 2 2 6 6 6 2 HEAT-like repeat DUF3554 PF12074.3 ETO03581.1 - 0.00013 21.4 8.2 0.058 12.8 0.1 4.8 2 2 3 6 6 6 2 Domain of unknown function (DUF3554) MOR2-PAG1_C PF14225.1 ETO03581.1 - 0.00035 20.4 7.1 0.39 10.4 0.0 4.3 3 1 1 5 5 5 1 Cell morphogenesis C-terminal NLE PF08154.7 ETO03581.1 - 0.00046 20.1 6.8 3.4 7.7 0.0 5.1 5 0 0 5 5 5 2 NLE (NUC135) domain Vac14_Fab1_bd PF12755.2 ETO03581.1 - 0.0018 18.6 4.6 0.82 10.0 0.0 4.7 1 1 3 5 5 5 1 Vacuolar 14 Fab1-binding region TIP120 PF08623.5 ETO03581.1 - 0.0043 16.6 12.7 0.5 9.9 0.1 4.6 2 1 3 5 5 5 2 TATA-binding protein interacting (TIP20) Lumazine_bd_2 PF12893.2 ETO03581.1 - 0.014 15.9 0.2 1.5 9.4 0.0 3.4 3 1 1 4 4 4 0 Putative lumazine-binding HEAT_PBS PF03130.11 ETO03581.1 - 0.014 15.7 0.0 42 5.0 0.0 4.5 6 0 0 6 6 3 0 PBS lyase HEAT-like repeat DUF2435 PF10363.4 ETO03581.1 - 0.016 15.1 6.9 0.18 11.7 0.1 5.0 4 1 1 5 5 5 0 Protein of unknown function (DUF2435) ENTH PF01417.15 ETO03581.1 - 0.063 13.1 4.3 2 8.2 0.0 3.6 3 1 1 4 4 4 0 ENTH domain Spore_III_AB PF09548.5 ETO03581.1 - 0.089 12.5 5.8 0.091 12.5 0.9 3.2 2 2 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Syntaphilin PF15290.1 ETO03581.1 - 0.098 12.1 6.4 0.71 9.3 0.0 3.5 2 1 2 4 4 4 0 Golgi-localised syntaxin-1-binding clamp Condensin2nSMC PF12422.3 ETO03581.1 - 0.22 11.2 2.8 1.2 8.8 0.2 3.0 1 1 2 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit Activator-TraM PF11657.3 ETO03581.1 - 0.32 10.4 4.3 0.2 11.1 0.1 2.8 3 0 0 3 3 3 0 Transcriptional activator TraM DUF2758 PF10957.3 ETO03581.1 - 8.5 6.2 8.5 47 3.9 0.1 4.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2758) COQ9 PF08511.6 ETO03582.1 - 0.056 12.9 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 COQ9 Transposase_mut PF00872.13 ETO03582.1 - 0.058 11.9 0.3 0.4 9.1 0.1 2.0 1 1 1 2 2 2 0 Transposase, Mutator family MutS_IV PF05190.13 ETO03582.1 - 0.076 13.2 0.9 0.22 11.7 0.1 2.3 2 0 0 2 2 2 0 MutS family domain IV Tctex-1 PF03645.8 ETO03582.1 - 0.24 11.2 3.5 0.38 10.6 1.6 1.9 2 0 0 2 2 2 0 Tctex-1 family Baculo_gp41 PF04700.7 ETO03582.1 - 0.35 10.2 3.4 0.56 9.6 0.6 2.1 1 1 0 2 2 2 0 Structural glycoprotein p40/gp41 conserved region SASRP1 PF15160.1 ETO03583.1 - 0.051 12.7 0.3 0.064 12.4 0.2 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated serine-rich protein 1 HTH_Crp_2 PF13545.1 ETO03583.1 - 0.087 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Cut8_N PF14482.1 ETO03583.1 - 0.2 11.6 2.3 0.47 10.4 1.6 1.6 1 1 0 1 1 1 0 Cut8 proteasome-binding domain Geminin PF07412.7 ETO03584.1 - 0.018 14.7 5.4 0.019 14.6 3.4 1.4 1 1 0 1 1 1 0 Geminin TPR_MLP1_2 PF07926.7 ETO03584.1 - 0.027 14.2 6.8 0.031 14.0 4.7 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF641 PF04859.7 ETO03584.1 - 0.13 12.0 6.1 0.14 11.8 4.2 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF724 PF05266.9 ETO03584.1 - 1.3 8.6 9.3 1.3 8.6 6.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Vfa1 PF08432.5 ETO03584.1 - 1.6 8.7 8.5 1.8 8.5 5.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1202 PF06717.6 ETO03584.1 - 2 7.6 9.0 1.9 7.6 6.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) OmpH PF03938.9 ETO03584.1 - 3 7.7 11.2 2.9 7.8 7.8 1.0 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Macoilin PF09726.4 ETO03584.1 - 3.8 5.6 8.2 4.2 5.5 5.7 1.0 1 0 0 1 1 1 0 Transmembrane protein PHTB1_N PF14727.1 ETO03584.1 - 4.6 6.0 6.3 5 5.9 4.4 1.0 1 0 0 1 1 1 0 PTHB1 N-terminus DUF4220 PF13968.1 ETO03585.1 - 0.079 12.0 0.2 0.089 11.8 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) MscL PF01741.13 ETO03585.1 - 0.083 13.0 1.5 0.1 12.7 0.0 1.8 2 0 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL DUF2207 PF09972.4 ETO03586.1 - 9.2 4.7 12.6 9.9 4.6 8.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Kelch_6 PF13964.1 ETO03587.1 - 0.00012 22.1 0.6 0.0017 18.4 0.0 2.7 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.20 ETO03587.1 - 0.00039 19.8 0.2 0.0066 15.9 0.1 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.10 ETO03587.1 - 0.11 12.3 1.4 1.2 8.9 0.1 3.2 3 2 0 3 3 3 0 Kelch motif Phage_GP20 PF06810.6 ETO03588.1 - 0.00092 18.6 18.7 0.00092 18.6 13.0 3.1 1 1 2 3 3 3 1 Phage minor structural protein GP20 TPR_MLP1_2 PF07926.7 ETO03588.1 - 0.00099 18.8 34.9 0.09 12.5 6.7 2.3 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein Pro-rich_19 PF15455.1 ETO03588.1 - 0.0018 17.3 0.3 0.0018 17.3 0.2 1.4 2 0 0 2 2 2 1 Proline-rich 19 IncA PF04156.9 ETO03588.1 - 0.044 13.3 35.2 0.23 11.0 4.3 2.1 1 1 1 2 2 2 0 IncA protein PilJ PF13675.1 ETO03588.1 - 0.13 12.5 4.7 0.54 10.6 0.5 2.3 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Reo_sigmaC PF04582.7 ETO03588.1 - 0.15 11.1 3.7 1.7 7.7 0.3 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Lebercilin PF15619.1 ETO03588.1 - 0.16 11.3 36.3 0.16 11.3 12.0 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.6 ETO03588.1 - 0.2 10.2 29.0 0.25 9.9 20.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3584 PF12128.3 ETO03588.1 - 0.32 8.2 28.5 0.45 7.7 19.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF972 PF06156.8 ETO03588.1 - 0.6 10.4 32.8 1.2 9.5 8.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF972) OsmC PF02566.14 ETO03588.1 - 1.1 9.4 5.1 0.32 11.1 0.5 2.0 2 1 0 2 2 2 0 OsmC-like protein DUF641 PF04859.7 ETO03588.1 - 1.2 8.8 24.6 0.064 13.0 4.6 2.9 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) Arena_RNA_pol PF06317.6 ETO03588.1 - 1.3 5.5 21.2 1.5 5.3 14.7 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase AAA_13 PF13166.1 ETO03588.1 - 1.9 6.8 35.1 24 3.2 24.4 2.0 1 1 0 1 1 1 0 AAA domain Tropomyosin_1 PF12718.2 ETO03588.1 - 2.4 7.9 38.8 1.7 8.4 7.6 2.7 1 1 1 2 2 2 0 Tropomyosin like EMP70 PF02990.11 ETO03588.1 - 5.6 5.3 9.3 6.4 5.1 6.4 1.2 1 0 0 1 1 1 0 Endomembrane protein 70 Fib_alpha PF08702.5 ETO03588.1 - 9 6.4 34.6 12 5.9 7.4 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1034 PF06280.7 ETO03588.1 - 9.4 6.6 10.3 0.93 9.9 1.4 2.2 2 0 0 2 2 2 0 Fn3-like domain (DUF1034) LA-virus_coat PF09220.5 ETO03589.1 - 0.021 13.2 0.0 0.028 12.8 0.0 1.1 1 0 0 1 1 1 0 L-A virus, major coat protein gp45-slide_C PF09116.5 ETO03589.1 - 0.048 13.6 0.3 0.089 12.7 0.2 1.4 1 0 0 1 1 1 0 gp45 sliding clamp, C terminal Cluap1 PF10234.4 ETO03590.1 - 2.5e-65 220.3 14.8 6.2e-47 160.0 0.4 2.3 2 0 0 2 2 2 2 Clusterin-associated protein-1 ArfGap PF01412.13 ETO03590.1 - 0.036 13.8 3.6 0.11 12.2 2.5 1.9 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf RibD_C PF01872.12 ETO03590.1 - 0.055 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 RibD C-terminal domain ER-remodelling PF14755.1 ETO03590.1 - 2.3 8.2 4.8 4.7 7.2 3.3 1.4 1 0 0 1 1 1 0 Intracellular membrane remodeller HSP70 PF00012.15 ETO03591.1 - 2.1e-13 49.1 4.1 2.1e-13 49.1 2.8 2.8 2 1 0 2 2 2 1 Hsp70 protein Peptidase_U57 PF05582.7 ETO03591.1 - 1 8.2 9.2 0.24 10.3 2.2 2.3 2 0 0 2 2 2 0 YabG peptidase U57 Pox_Ag35 PF03286.9 ETO03591.1 - 1.4 8.3 28.7 0.7 9.3 11.6 2.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein TLP-20 PF06088.6 ETO03591.1 - 2.2 7.9 13.6 1.1 8.8 4.4 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) HSP70 PF00012.15 ETO03592.1 - 1.2e-29 102.6 0.2 1.5e-29 102.3 0.2 1.0 1 0 0 1 1 1 1 Hsp70 protein DUF4047 PF13256.1 ETO03592.1 - 0.11 12.4 0.2 0.17 11.8 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) Ribosomal_S4 PF00163.14 ETO03593.1 - 7.4e-20 71.1 1.0 7.4e-20 71.1 0.7 2.1 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 ETO03593.1 - 9.6e-07 28.1 0.8 9.6e-07 28.1 0.6 1.9 2 0 0 2 2 2 1 S4 domain Orthopox_F6 PF06601.7 ETO03593.1 - 0.037 13.9 1.0 0.081 12.8 0.7 1.5 1 0 0 1 1 1 0 Orthopoxvirus F6 protein Spore_YhcN_YlaJ PF09580.5 ETO03593.1 - 0.094 12.8 0.1 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF21 PF01595.15 ETO03594.1 - 0.26 10.5 8.7 0.035 13.4 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF21 RGS PF00615.14 ETO03595.1 - 0.0004 20.4 6.8 0.0012 18.8 0.6 2.5 2 1 0 2 2 2 2 Regulator of G protein signaling domain DnaJ PF00226.26 ETO03596.1 - 3e-17 62.0 2.1 5.3e-17 61.3 1.4 1.4 1 0 0 1 1 1 1 DnaJ domain Endotoxin_N PF03945.9 ETO03596.1 - 0.01 15.2 1.4 0.016 14.6 0.7 1.5 1 1 1 2 2 2 0 delta endotoxin, N-terminal domain DUF2802 PF10975.3 ETO03597.1 - 0.013 15.2 4.0 0.041 13.6 2.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) GAS2 PF02187.12 ETO03597.1 - 0.014 15.1 0.3 0.039 13.7 0.1 1.8 1 1 1 2 2 2 0 Growth-Arrest-Specific Protein 2 Domain Spc24 PF08286.6 ETO03597.1 - 1.5 8.4 7.2 0.63 9.7 3.1 1.7 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 GrpE PF01025.14 ETO03597.1 - 6.5 6.2 9.8 19 4.7 6.8 1.7 1 1 0 1 1 1 0 GrpE DUF4200 PF13863.1 ETO03597.1 - 7.7 6.4 16.1 4.6 7.2 7.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF4407 PF14362.1 ETO03597.1 - 9.7 5.0 9.2 12 4.7 6.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Hist_deacetyl PF00850.14 ETO03598.1 - 0.021 14.0 0.3 0.025 13.8 0.2 1.0 1 0 0 1 1 1 0 Histone deacetylase domain AhpC-TSA PF00578.16 ETO03598.1 - 0.055 13.1 0.3 0.084 12.5 0.1 1.4 1 1 0 1 1 1 0 AhpC/TSA family DUF3116 PF11313.3 ETO03598.1 - 0.072 12.7 1.4 0.36 10.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3116) ATP-synt_F PF01990.12 ETO03598.1 - 0.095 13.0 0.5 0.11 12.8 0.3 1.3 1 1 0 1 1 1 0 ATP synthase (F/14-kDa) subunit YolD PF08863.5 ETO03600.1 - 0.026 14.3 0.8 0.044 13.6 0.5 1.3 1 0 0 1 1 1 0 YolD-like protein CDC50 PF03381.10 ETO03601.1 - 1.2e-15 57.4 1.1 1.3e-15 57.3 0.8 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Phage_T4_gp19 PF06841.7 ETO03601.1 - 0.1 12.1 0.3 0.15 11.7 0.2 1.3 1 0 0 1 1 1 0 T4-like virus tail tube protein gp19 WD40 PF00400.27 ETO03602.1 - 5.4e-51 168.7 25.4 1e-10 41.0 0.5 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO03602.1 - 1.3e-11 43.4 6.7 0.00059 18.1 0.2 4.9 2 1 3 5 5 5 4 Nucleoporin Nup120/160 HAD PF12710.2 ETO03602.1 - 0.039 14.1 1.1 15 5.6 0.0 3.6 2 2 1 3 3 3 0 haloacid dehalogenase-like hydrolase DUF1498 PF07385.7 ETO03602.1 - 0.059 12.4 0.4 0.16 11.0 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1498) JTB PF05439.7 ETO03603.1 - 0.0071 16.1 3.9 0.013 15.3 2.7 1.5 1 1 0 1 1 1 1 Jumping translocation breakpoint protein (JTB) DUP PF00674.13 ETO03604.1 - 0.022 14.7 0.2 0.03 14.2 0.1 1.2 1 0 0 1 1 1 0 DUP family Paf1 PF03985.8 ETO03604.1 - 0.2 10.3 12.1 0.21 10.2 8.4 1.2 1 0 0 1 1 1 0 Paf1 DUF2457 PF10446.4 ETO03604.1 - 0.33 9.6 15.7 0.32 9.6 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF4484 PF14831.1 ETO03604.1 - 0.57 10.2 4.8 0.75 9.8 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Prothymosin PF03247.9 ETO03604.1 - 0.73 10.0 29.2 10 6.2 17.3 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family Nop14 PF04147.7 ETO03604.1 - 0.93 7.3 16.7 0.88 7.4 11.6 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 ETO03604.1 - 3.4 5.5 11.9 3.5 5.5 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein COPI_C PF06957.6 ETO03604.1 - 3.5 6.0 8.1 3.9 5.9 5.6 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus MyTH4 PF00784.12 ETO03605.1 - 8e-25 87.0 1.8 9.9e-25 86.7 0.1 1.9 2 0 0 2 2 2 1 MyTH4 domain DNApol3-delta_C PF09115.5 ETO03606.1 - 1.9 8.5 8.0 0.75 9.8 2.7 2.3 3 0 0 3 3 3 0 DNA polymerase III, delta subunit, C terminal DUF2893 PF11459.3 ETO03607.1 - 0.04 13.7 0.1 0.14 11.9 0.1 1.9 1 0 0 1 1 1 0 Protein of unknwon function (DUF2893) CENP-R PF06729.7 ETO03607.1 - 8.7 6.0 10.0 0.19 11.4 1.8 2.0 2 0 0 2 2 2 0 Kinetochore component, CENP-R DIRP PF06584.8 ETO03608.1 - 0.012 15.5 0.0 2.4 8.0 0.0 2.7 2 0 0 2 2 2 0 DIRP hDGE_amylase PF14701.1 ETO03609.1 - 0.12 11.3 11.5 0.2 10.5 8.0 1.4 1 1 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme WD40 PF00400.27 ETO03610.1 - 2.9e-45 150.5 6.1 2e-12 46.4 0.0 4.0 4 0 0 4 4 4 4 WD domain, G-beta repeat eIF2A PF08662.6 ETO03610.1 - 1.3e-07 31.5 0.1 6.1e-06 26.0 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO03610.1 - 0.00026 19.2 0.7 0.21 9.6 0.0 3.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO03610.1 - 0.00033 20.1 0.5 0.016 14.5 0.0 2.6 1 1 2 3 3 3 1 Domain of unknown function (DUF4221) DUF1258 PF06869.7 ETO03610.1 - 0.0016 17.5 0.4 2.2 7.2 0.0 2.9 1 1 2 3 3 3 2 Protein of unknown function (DUF1258) Coatomer_WDAD PF04053.9 ETO03610.1 - 0.019 13.7 0.3 0.024 13.4 0.2 1.1 1 0 0 1 1 1 0 Coatomer WD associated region PQQ_2 PF13360.1 ETO03610.1 - 0.026 13.9 0.0 2.8 7.3 0.0 2.1 1 1 1 2 2 2 0 PQQ-like domain Arylsulfotran_2 PF14269.1 ETO03610.1 - 0.055 12.6 1.0 5.4 6.0 0.1 2.2 1 1 0 2 2 2 0 Arylsulfotransferase (ASST) PQQ PF01011.16 ETO03610.1 - 0.056 13.0 0.0 13 5.5 0.0 3.2 3 0 0 3 3 3 0 PQQ enzyme repeat DPPIV_N PF00930.16 ETO03610.1 - 0.058 11.9 0.0 1.9 6.9 0.0 2.1 1 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Cytochrom_D1 PF02239.11 ETO03610.1 - 0.078 11.2 0.0 0.11 10.7 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain eIF-5_eIF-2B PF01873.12 ETO03611.1 - 9e-33 112.5 0.7 1.3e-32 112.0 0.5 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 RRN7 PF11781.3 ETO03611.1 - 0.048 13.1 0.1 7.5 6.1 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 tRNA-synt_1f PF01921.13 ETO03611.1 - 0.092 11.3 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (K) WD40 PF00400.27 ETO03612.1 - 4.8e-65 213.3 25.5 3.1e-13 49.0 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat PQQ_2 PF13360.1 ETO03612.1 - 1.3e-09 37.9 4.6 0.0005 19.6 0.1 3.1 1 1 1 3 3 3 3 PQQ-like domain Cytochrom_D1 PF02239.11 ETO03612.1 - 5.2e-07 28.2 3.3 0.0029 15.9 0.1 3.3 1 1 1 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.3 ETO03612.1 - 5.8e-07 28.0 5.4 0.14 10.2 0.3 3.5 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Me-amine-dh_H PF06433.6 ETO03612.1 - 5.6e-05 21.9 0.0 0.59 8.7 0.0 3.3 1 1 1 3 3 3 3 Methylamine dehydrogenase heavy chain (MADH) Nucleoporin_N PF08801.6 ETO03612.1 - 0.00019 20.2 13.9 0.019 13.6 1.6 3.9 1 1 2 3 3 3 2 Nup133 N terminal like PD40 PF07676.7 ETO03612.1 - 0.00092 18.8 8.1 5.8 6.6 0.0 6.2 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat CPSF_A PF03178.10 ETO03612.1 - 0.013 14.6 0.4 9.6 5.1 0.0 3.2 1 1 2 3 3 3 0 CPSF A subunit region Hira PF07569.6 ETO03612.1 - 0.019 14.2 1.2 0.64 9.1 0.0 3.3 2 1 2 4 4 4 0 TUP1-like enhancer of split DUF2963 PF11178.3 ETO03612.1 - 0.021 14.2 4.0 13 5.2 0.1 4.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2963) DUF3732 PF12532.3 ETO03612.1 - 0.059 12.8 1.5 4.2 6.8 0.0 3.5 2 1 1 4 4 4 0 Protein of unknown function (DUF3732) Proteasome_A_N PF10584.4 ETO03612.1 - 1.4 8.3 4.2 50 3.3 0.1 4.3 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 ETO03613.1 - 2.5e-51 169.8 20.1 2.1e-13 49.5 0.2 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO03613.1 - 1.6e-09 37.7 0.4 0.0015 18.2 0.0 3.4 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO03613.1 - 3.1e-07 28.9 3.2 0.11 10.5 0.0 4.4 1 1 3 4 4 4 4 Nucleoporin Nup120/160 PD40 PF07676.7 ETO03613.1 - 6.1e-06 25.7 7.1 4 7.2 0.0 5.6 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO03613.1 - 1.2e-05 23.8 0.0 0.06 11.6 0.0 2.5 2 1 1 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO03613.1 - 7.7e-05 21.6 7.7 0.61 8.7 2.2 4.2 1 1 2 3 3 3 2 Nup133 N terminal like Resistin PF06954.6 ETO03613.1 - 0.00047 20.3 2.5 3.9 7.8 0.0 4.3 1 1 2 4 4 4 1 Resistin Str_synth PF03088.11 ETO03613.1 - 0.00054 19.9 0.3 9.3 6.3 0.0 4.7 3 2 1 5 5 5 1 Strictosidine synthase Ricin_B_lectin PF00652.17 ETO03613.1 - 0.00082 19.3 2.1 0.2 11.6 0.2 2.9 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain Coatomer_WDAD PF04053.9 ETO03613.1 - 0.019 13.8 1.6 1.1 8.0 0.4 2.2 1 1 1 2 2 2 0 Coatomer WD associated region Hira PF07569.6 ETO03613.1 - 0.019 14.1 1.7 1.6 7.8 0.2 3.3 3 2 1 4 4 4 0 TUP1-like enhancer of split HPS3_N PF14761.1 ETO03613.1 - 0.039 13.3 0.1 0.083 12.2 0.0 1.5 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 WD40 PF00400.27 ETO03614.1 - 2.4e-73 239.6 18.1 4.6e-12 45.3 0.1 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat Kelch_4 PF13418.1 ETO03614.1 - 5.9e-05 22.7 0.5 0.0028 17.3 0.0 3.5 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO03614.1 - 0.00066 19.1 3.9 0.00098 18.6 0.2 2.9 3 0 0 3 3 3 1 Kelch motif PQQ_2 PF13360.1 ETO03614.1 - 0.00096 18.6 0.1 0.0026 17.2 0.1 1.7 1 1 0 1 1 1 1 PQQ-like domain PD40 PF07676.7 ETO03614.1 - 0.012 15.2 9.4 9 6.0 0.1 5.9 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Kelch_6 PF13964.1 ETO03614.1 - 0.062 13.4 4.6 9.4 6.5 0.2 4.5 4 0 0 4 4 4 0 Kelch motif Proteasome_A_N PF10584.4 ETO03614.1 - 0.19 11.0 4.0 15 5.0 0.0 4.0 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature DUF912 PF06024.7 ETO03615.1 - 0.0017 18.3 0.2 0.0017 18.3 0.2 1.6 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Otopetrin PF03189.8 ETO03615.1 - 0.0025 16.9 0.6 0.0032 16.5 0.4 1.1 1 0 0 1 1 1 1 Otopetrin DUF3307 PF11750.3 ETO03615.1 - 0.051 13.3 0.3 0.1 12.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3307) ETRAMP PF09716.5 ETO03615.1 - 0.056 13.3 2.6 0.089 12.7 0.1 2.2 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) DUF2975 PF11188.3 ETO03615.1 - 0.064 12.9 3.8 0.86 9.3 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2975) UPF0233 PF06781.7 ETO03615.1 - 0.065 12.8 0.7 0.23 11.1 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) DUF2427 PF10348.4 ETO03615.1 - 0.091 12.3 0.7 0.17 11.4 0.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) DUF3464 PF11947.3 ETO03615.1 - 0.093 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF1183 PF06682.7 ETO03615.1 - 0.12 11.9 0.2 4.5 6.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) Neurensin PF14927.1 ETO03615.1 - 0.44 9.9 2.0 1.5 8.1 0.0 2.2 1 1 0 2 2 2 0 Neurensin Kelch_1 PF01344.20 ETO03617.1 - 0.003 17.0 0.6 0.0053 16.2 0.1 1.7 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETO03617.1 - 0.05 13.8 0.7 4.3 7.6 0.1 2.3 2 0 0 2 2 2 0 Kelch motif Kelch_2 PF07646.10 ETO03617.1 - 0.065 13.0 2.1 2.2 8.1 0.1 2.5 2 1 0 2 2 2 0 Kelch motif Sina PF03145.11 ETO03618.1 - 0.016 14.8 0.2 0.14 11.7 0.0 1.9 1 1 1 2 2 2 0 Seven in absentia protein family Treslin_N PF15292.1 ETO03618.1 - 0.042 11.7 0.7 0.046 11.6 0.5 1.0 1 0 0 1 1 1 0 Treslin N-terminus WD40 PF00400.27 ETO03620.1 - 3.8e-13 48.7 0.4 1.2e-10 40.8 0.3 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat zf-TRAF PF02176.13 ETO03621.1 - 0.00029 21.1 6.9 0.00029 21.1 4.8 2.7 2 1 1 3 3 2 1 TRAF-type zinc finger UvrD-helicase PF00580.16 ETO03621.1 - 0.004 16.5 4.8 0.0051 16.1 3.3 1.2 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Cep57_CLD_2 PF14197.1 ETO03621.1 - 0.0085 16.0 4.0 0.03 14.2 2.8 1.9 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 PSP1 PF04468.7 ETO03621.1 - 0.052 13.5 1.4 0.47 10.4 0.1 2.4 2 0 0 2 2 2 0 PSP1 C-terminal conserved region TSC22 PF01166.13 ETO03621.1 - 0.62 10.0 10.3 0.14 12.0 1.4 3.0 3 0 0 3 3 3 0 TSC-22/dip/bun family DUF972 PF06156.8 ETO03621.1 - 0.85 9.9 11.2 0.091 13.1 4.2 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF972) IncA PF04156.9 ETO03621.1 - 0.98 8.9 7.1 0.45 10.0 3.4 1.5 2 0 0 2 2 2 0 IncA protein DUF342 PF03961.8 ETO03621.1 - 0.98 7.7 6.5 1.2 7.4 4.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) bZIP_1 PF00170.16 ETO03621.1 - 2.3 8.2 8.6 4.6 7.2 4.8 2.3 1 1 1 2 2 2 0 bZIP transcription factor AAA_23 PF13476.1 ETO03621.1 - 2.4 8.4 11.0 3.1 8.0 7.6 1.3 1 1 0 1 1 1 0 AAA domain DUF904 PF06005.7 ETO03621.1 - 6.9 7.0 13.8 6 7.2 7.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Presenilin PF01080.12 ETO03625.1 - 4.7e-06 25.6 1.7 6.2e-06 25.2 1.2 1.1 1 0 0 1 1 1 1 Presenilin Peptidase_M50B PF13398.1 ETO03625.1 - 0.0033 16.8 5.0 0.0055 16.1 3.5 1.3 1 0 0 1 1 1 1 Peptidase M50B-like DUF4436 PF14494.1 ETO03625.1 - 0.0048 16.2 1.9 0.0048 16.2 1.3 2.2 2 1 1 3 3 3 1 Domain of unknown function (DUF4436) DUF4131 PF13567.1 ETO03625.1 - 0.0066 15.8 1.4 0.0066 15.8 0.9 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4131) Wzy_C PF04932.10 ETO03625.1 - 0.046 13.5 3.5 0.045 13.5 1.7 1.5 1 1 0 1 1 1 0 O-Antigen ligase DUF4149 PF13664.1 ETO03625.1 - 0.067 13.2 2.1 0.11 12.5 1.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) SelP_N PF04592.9 ETO03625.1 - 0.24 10.7 7.4 0.4 10.0 5.2 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF457 PF04307.9 ETO03625.1 - 3.3 7.0 8.5 11 5.3 5.9 1.9 1 1 0 1 1 1 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) Cyc-maltodext_C PF10438.4 ETO03626.1 - 0.03 14.3 0.1 0.051 13.6 0.0 1.4 1 1 0 1 1 1 0 Cyclo-malto-dextrinase C-terminal domain Transcrip_act PF04949.8 ETO03626.1 - 0.044 13.4 1.4 0.05 13.2 0.9 1.1 1 0 0 1 1 1 0 Transcriptional activator USP8_dimer PF08969.6 ETO03626.1 - 0.064 13.2 0.3 0.091 12.7 0.2 1.2 1 0 0 1 1 1 0 USP8 dimerisation domain Kelch_6 PF13964.1 ETO03627.1 - 0.09 12.9 0.2 15 5.9 0.0 2.1 1 1 1 2 2 2 0 Kelch motif L_lactis_ph-MCP PF06673.6 ETO03627.1 - 0.71 8.5 3.8 0.93 8.2 2.6 1.1 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein Peptidase_S41 PF03572.13 ETO03628.1 - 0.0055 16.1 0.1 0.0093 15.3 0.0 1.4 1 1 0 1 1 1 1 Peptidase family S41 DUF99 PF01949.11 ETO03628.1 - 0.036 13.1 0.2 0.092 11.8 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function DUF99 PapB PF03333.8 ETO03628.1 - 0.078 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Adhesin biosynthesis transcription regulatory protein AHS1 PF02682.11 ETO03628.1 - 0.13 11.7 0.0 0.23 10.8 0.0 1.5 1 1 0 1 1 1 0 Allophanate hydrolase subunit 1 RRM_3 PF08777.6 ETO03628.1 - 0.29 10.9 3.5 0.34 10.7 0.0 2.3 2 1 0 2 2 2 0 RNA binding motif IBR PF01485.16 ETO03629.1 - 1.8e-05 24.5 25.8 0.0035 17.1 4.3 3.1 2 1 0 2 2 2 2 IBR domain FYVE PF01363.16 ETO03629.1 - 3.4 7.6 28.1 2.5 8.0 10.5 2.7 1 1 1 2 2 2 0 FYVE zinc finger La PF05383.12 ETO03630.1 - 2.6e-07 30.3 0.0 4.7e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 La domain DUF399 PF04187.8 ETO03630.1 - 0.15 11.5 4.7 0.18 11.2 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF399 BLVR PF06375.6 ETO03630.1 - 0.46 10.2 10.6 0.5 10.1 6.6 1.4 1 1 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) VWA_2 PF13519.1 ETO03631.1 - 1.6e-06 28.3 0.0 2.5e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain HAUS5 PF14817.1 ETO03631.1 - 0.049 12.1 0.1 0.062 11.8 0.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 SLA_LP_auto_ag PF05889.8 ETO03631.1 - 0.06 11.8 0.1 0.077 11.4 0.0 1.1 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) PPR PF01535.15 ETO03632.1 - 2e-17 61.8 6.5 0.00012 21.8 0.0 4.7 5 0 0 5 5 5 4 PPR repeat PPR_2 PF13041.1 ETO03632.1 - 1.2e-15 57.1 9.5 8.1e-10 38.5 0.2 4.3 2 1 3 5 5 5 4 PPR repeat family PPR_3 PF13812.1 ETO03632.1 - 2.7e-14 52.1 0.1 2.1e-05 24.4 0.0 4.6 5 0 0 5 5 5 3 Pentatricopeptide repeat domain PPR_1 PF12854.2 ETO03632.1 - 3.9e-10 39.0 3.0 0.0012 18.2 0.0 4.0 5 0 0 5 5 5 3 PPR repeat ATP13 PF12921.2 ETO03632.1 - 0.016 14.5 1.4 2 7.7 0.1 2.9 2 1 1 3 3 3 0 Mitochondrial ATPase expression CENP-B_dimeris PF09026.5 ETO03633.1 - 7.6e-05 22.8 14.5 7.6e-05 22.8 10.1 2.0 2 0 0 2 2 2 1 Centromere protein B dimerisation domain Daxx PF03344.10 ETO03633.1 - 0.0079 14.7 35.5 0.01 14.4 24.6 1.2 1 0 0 1 1 1 1 Daxx Family MIP-T3 PF10243.4 ETO03633.1 - 0.12 10.8 41.1 0.13 10.7 28.5 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CDC27 PF09507.5 ETO03633.1 - 0.21 10.7 37.7 0.25 10.5 26.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nop25 PF09805.4 ETO03633.1 - 0.55 10.2 42.4 0.68 9.9 29.4 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Cwf_Cwc_15 PF04889.7 ETO03633.1 - 0.58 9.8 41.7 0.76 9.4 28.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 ETO03633.1 - 0.7 7.7 37.8 0.79 7.5 26.2 1.1 1 0 0 1 1 1 0 Nop14-like family Spc7_N PF15402.1 ETO03633.1 - 1.9 6.4 24.4 2.1 6.2 16.9 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF1777 PF08648.7 ETO03633.1 - 4.8 6.8 33.2 5.8 6.6 23.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) BTV_NS2 PF04514.7 ETO03633.1 - 5.2 5.8 30.1 7.1 5.4 20.8 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FAM60A PF15396.1 ETO03633.1 - 8.3 6.0 22.3 11 5.6 15.4 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Glyco_hydro_47 PF01532.15 ETO03634.1 - 0.00028 19.6 0.0 0.00036 19.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 KxDL PF10241.4 ETO03635.1 - 0.087 12.7 1.8 0.1 12.5 0.2 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein NAF PF03822.9 ETO03635.1 - 0.088 12.5 0.4 0.2 11.3 0.3 1.6 1 0 0 1 1 1 0 NAF domain Autophagy_N PF03986.8 ETO03636.1 - 0.79 9.4 6.3 0.88 9.3 4.4 1.0 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain Lin-8 PF03353.10 ETO03636.1 - 3.1 6.9 9.3 3.8 6.7 6.4 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Daxx PF03344.10 ETO03636.1 - 3.4 6.0 15.6 4 5.8 10.8 1.0 1 0 0 1 1 1 0 Daxx Family Spore_coat_CotO PF14153.1 ETO03636.1 - 4.3 6.7 9.1 4.7 6.6 6.3 1.0 1 0 0 1 1 1 0 Spore coat protein CotO Vfa1 PF08432.5 ETO03636.1 - 7.3 6.5 11.7 8.5 6.3 8.1 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF740 PF05340.7 ETO03636.1 - 8.9 4.5 8.1 9.6 4.4 5.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF740) HEAT_2 PF13646.1 ETO03637.1 - 3e-20 72.2 0.0 4e-11 43.0 0.0 2.2 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 ETO03637.1 - 1.6e-14 52.6 0.0 0.00027 20.7 0.0 3.6 3 0 0 3 3 3 3 HEAT repeat HEAT_EZ PF13513.1 ETO03637.1 - 1.8e-09 37.7 0.0 0.0001 22.6 0.0 2.4 2 0 0 2 2 2 2 HEAT-like repeat HEAT_PBS PF03130.11 ETO03637.1 - 4.6e-05 23.4 0.0 2.8 8.6 0.0 3.5 3 0 0 3 3 3 2 PBS lyase HEAT-like repeat DUF2435 PF10363.4 ETO03637.1 - 6.2e-05 22.8 0.6 0.001 18.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) Vac14_Fab1_bd PF12755.2 ETO03637.1 - 0.00014 22.1 0.1 0.0035 17.6 0.1 2.4 1 1 1 2 2 2 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 ETO03637.1 - 0.00038 18.9 3.1 0.00048 18.5 2.1 1.2 1 0 0 1 1 1 1 Adaptin N terminal region CLASP_N PF12348.3 ETO03637.1 - 0.00039 19.8 1.9 0.00073 18.9 0.1 1.9 2 0 0 2 2 2 1 CLASP N terminal MOR2-PAG1_C PF14225.1 ETO03637.1 - 0.0016 18.2 0.8 0.14 11.8 0.1 2.4 1 1 2 3 3 3 1 Cell morphogenesis C-terminal NLE PF08154.7 ETO03637.1 - 0.0019 18.1 0.4 2.9 7.9 0.0 3.2 4 0 0 4 4 4 1 NLE (NUC135) domain DUF3554 PF12074.3 ETO03637.1 - 0.0031 16.9 3.0 0.79 9.0 0.0 2.7 1 1 2 3 3 3 2 Domain of unknown function (DUF3554) TIP120 PF08623.5 ETO03637.1 - 0.0056 16.2 0.2 0.018 14.6 0.2 1.9 1 1 0 1 1 1 1 TATA-binding protein interacting (TIP20) DUF3810 PF12725.2 ETO03637.1 - 0.018 13.9 0.3 1.3 7.8 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) FLO_LFY PF01698.11 ETO03637.1 - 0.019 13.8 0.0 0.035 12.9 0.0 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein IFRD PF05004.8 ETO03637.1 - 0.032 13.3 0.1 4.7 6.1 0.0 2.3 1 1 1 2 2 2 0 Interferon-related developmental regulator (IFRD) Rep_trans PF02486.14 ETO03637.1 - 0.044 13.2 0.6 2.1 7.8 0.0 2.8 1 1 1 2 2 2 0 Replication initiation factor Cnd1 PF12717.2 ETO03637.1 - 0.052 13.4 2.1 0.29 10.9 1.1 2.7 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 ENTH PF01417.15 ETO03637.1 - 0.081 12.7 0.9 0.98 9.2 0.1 2.6 2 1 0 2 2 2 0 ENTH domain DUF2758 PF10957.3 ETO03637.1 - 0.14 11.9 0.7 20 5.1 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2758) RGS PF00615.14 ETO03638.1 - 0.00054 20.0 8.6 0.00099 19.2 4.5 2.4 1 1 1 2 2 2 1 Regulator of G protein signaling domain DUF2615 PF11027.3 ETO03638.1 - 0.22 11.4 2.4 9.9 6.1 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2615) Ion_trans PF00520.26 ETO03639.1 - 2.2e-13 49.9 15.4 4.3e-13 48.9 10.7 1.5 1 0 0 1 1 1 1 Ion transport protein EST1 PF10374.4 ETO03640.1 - 0.083 12.8 8.2 0.11 12.4 5.7 1.3 1 0 0 1 1 1 0 Telomerase activating protein Est1 Pkr1 PF08636.5 ETO03640.1 - 0.21 11.6 2.3 0.44 10.6 0.0 2.5 2 1 0 2 2 2 0 ER protein Pkr1 Sugar_tr PF00083.19 ETO03640.1 - 0.81 8.1 6.6 0.024 13.2 0.4 1.5 2 0 0 2 2 2 0 Sugar (and other) transporter DUF2681 PF10883.3 ETO03640.1 - 0.82 9.9 15.2 0.19 11.9 6.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) COesterase PF00135.23 ETO03642.1 - 1.4e-05 24.0 0.0 1.4e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family zf-RING_2 PF13639.1 ETO03643.1 - 2.1e-11 43.4 11.1 3.7e-11 42.6 7.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 ETO03643.1 - 4.8e-11 42.1 9.9 9.2e-11 41.2 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO03643.1 - 4.9e-11 42.1 6.5 4.9e-11 42.1 4.5 1.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO03643.1 - 5.3e-10 39.1 11.3 1e-09 38.2 7.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO03643.1 - 8.5e-08 31.8 8.6 1.7e-07 30.8 5.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 ETO03643.1 - 2e-07 30.7 11.1 4.4e-07 29.6 7.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 ETO03643.1 - 6.3e-06 26.1 8.9 2.2e-05 24.4 6.2 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 ETO03643.1 - 6.4e-05 22.5 8.2 0.00017 21.2 5.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 ETO03643.1 - 0.0004 20.1 5.1 0.00081 19.1 3.5 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 ETO03643.1 - 0.0012 18.6 2.8 0.0029 17.3 1.9 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.10 ETO03643.1 - 0.0057 16.5 0.1 0.017 15.0 0.0 1.8 2 0 0 2 2 2 1 U-box domain YdjO PF14169.1 ETO03643.1 - 0.0086 15.5 3.9 1.3 8.4 0.2 3.7 3 0 0 3 3 3 1 Cold-inducible protein YdjO Rad50_zn_hook PF04423.9 ETO03643.1 - 0.0099 15.3 5.1 0.12 11.8 0.1 3.0 3 0 0 3 3 3 1 Rad50 zinc hook motif Helicase_C PF00271.26 ETO03643.1 - 0.01 15.6 0.1 0.022 14.6 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain zf-RING_4 PF14570.1 ETO03643.1 - 0.039 13.5 7.7 0.078 12.5 5.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain AAA_12 PF13087.1 ETO03643.1 - 0.049 13.0 0.5 0.061 12.7 0.4 1.2 1 0 0 1 1 1 0 AAA domain zf-MIZ PF02891.15 ETO03643.1 - 0.14 11.7 8.9 0.33 10.5 6.2 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Peptidase_S49_N PF08496.5 ETO03643.1 - 0.88 9.3 4.0 0.65 9.7 1.7 1.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DZR PF12773.2 ETO03643.1 - 1.5 8.6 5.8 9.4 6.1 4.0 2.1 1 1 1 2 2 2 0 Double zinc ribbon Prok-RING_4 PF14447.1 ETO03643.1 - 1.9 8.0 8.4 5.6 6.5 5.9 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 IBR PF01485.16 ETO03643.1 - 2.8 7.8 10.0 6.7 6.6 6.0 2.4 2 1 0 2 2 2 0 IBR domain zf-C2H2_2 PF12756.2 ETO03643.1 - 4.8 7.3 9.2 0.17 12.0 1.6 2.1 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) PPR_3 PF13812.1 ETO03644.1 - 1.4e-12 46.7 0.0 0.0015 18.6 0.0 3.1 3 0 0 3 3 3 3 Pentatricopeptide repeat domain PPR PF01535.15 ETO03644.1 - 1.9e-11 43.1 4.5 0.014 15.2 0.1 3.2 3 0 0 3 3 3 3 PPR repeat PPR_2 PF13041.1 ETO03644.1 - 3.7e-10 39.6 1.1 5.8e-07 29.3 0.1 2.8 2 1 1 3 3 3 3 PPR repeat family DUF3636 PF12331.3 ETO03644.1 - 0.0034 16.9 0.2 0.0053 16.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) PPR_1 PF12854.2 ETO03644.1 - 0.26 10.7 5.8 0.3 10.6 0.0 3.3 4 0 0 4 4 4 0 PPR repeat UBA_4 PF14555.1 ETO03645.1 - 8.5e-08 31.6 0.1 3.4e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 UBA-like domain SPOUT_MTase PF02590.12 ETO03645.1 - 0.05 13.3 4.3 0.033 13.9 1.1 2.1 2 0 0 2 2 2 0 Predicted SPOUT methyltransferase Papo_T_antigen PF02380.10 ETO03645.1 - 0.058 13.3 3.0 0.13 12.2 2.1 1.5 1 0 0 1 1 1 0 T-antigen specific domain HTH_25 PF13413.1 ETO03645.1 - 0.097 12.3 0.1 0.23 11.1 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HEAT PF02985.17 ETO03646.1 - 7.8e-12 44.2 0.0 1.9e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.1 ETO03646.1 - 6.3e-09 36.0 0.0 2.2e-08 34.2 0.0 1.6 1 1 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.1 ETO03646.1 - 1.2e-06 28.8 0.0 0.0002 21.7 0.0 2.1 1 1 1 2 2 2 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 ETO03646.1 - 0.0014 19.0 0.1 0.2 12.0 0.0 1.9 1 1 1 2 2 2 2 Vacuolar 14 Fab1-binding region Cnd3 PF12719.2 ETO03646.1 - 0.013 14.4 0.0 0.015 14.3 0.0 1.1 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain DUF3554 PF12074.3 ETO03646.1 - 0.015 14.7 0.0 0.027 13.8 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3554) DUF2608 PF11019.3 ETO03646.1 - 0.035 13.1 0.1 0.035 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) HEAT_PBS PF03130.11 ETO03646.1 - 0.039 14.4 0.0 15 6.4 0.0 3.1 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat LXG PF04740.7 ETO03646.1 - 0.074 12.8 0.4 0.081 12.7 0.3 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily Arm PF00514.18 ETO03646.1 - 0.076 12.8 0.0 2.1 8.3 0.0 2.2 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat TIP120 PF08623.5 ETO03646.1 - 0.13 11.8 1.6 2.6 7.5 0.0 2.0 1 1 1 2 2 2 0 TATA-binding protein interacting (TIP20) ArgJ PF01960.13 ETO03646.1 - 0.13 10.6 0.0 0.13 10.5 0.0 1.1 1 0 0 1 1 1 0 ArgJ family GEMIN8 PF15348.1 ETO03647.1 - 1.5 8.8 9.4 1.7 8.6 6.5 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 PspB PF06667.7 ETO03647.1 - 2 8.4 6.3 0.3 11.0 0.4 2.4 2 1 0 2 2 2 0 Phage shock protein B STAT_alpha PF01017.15 ETO03647.1 - 7.9 6.1 21.6 2.2 7.9 9.4 2.0 1 1 1 2 2 2 0 STAT protein, all-alpha domain DSPn PF14671.1 ETO03648.1 - 0.044 13.7 0.1 0.057 13.4 0.1 1.2 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half tRNA_anti-codon PF01336.20 ETO03649.1 - 2.3e-05 24.1 0.1 3.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Beta_propel PF09826.4 ETO03649.1 - 0.0096 14.3 0.0 0.0099 14.2 0.0 1.1 1 0 0 1 1 1 1 Beta propeller domain WD40 PF00400.27 ETO03650.1 - 2.9e-36 122.0 16.6 7.1e-10 38.3 0.2 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO03650.1 - 0.022 12.8 0.8 0.094 10.8 0.2 1.8 1 1 0 2 2 2 0 Nucleoporin Nup120/160 TPR_12 PF13424.1 ETO03651.1 - 1.5e-36 124.1 0.4 2.3e-20 72.2 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO03651.1 - 5.4e-19 67.6 3.3 7.3e-13 47.9 0.1 2.1 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETO03651.1 - 3.4e-18 64.3 4.4 3.4e-08 32.7 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO03651.1 - 3.9e-17 61.5 0.0 5.1e-07 29.4 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO03651.1 - 2.3e-16 58.1 0.0 3.7e-06 26.3 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO03651.1 - 1.8e-14 52.3 0.8 7e-06 25.5 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO03651.1 - 1.9e-11 42.9 12.2 7.2e-06 25.4 0.4 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO03651.1 - 3.8e-07 29.7 0.5 0.013 15.6 0.1 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO03651.1 - 5.3e-07 30.1 0.0 0.0002 21.9 0.0 1.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO03651.1 - 1.9e-05 24.8 0.1 0.16 12.4 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO03651.1 - 0.00041 20.7 0.0 0.066 13.8 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat MIT PF04212.13 ETO03651.1 - 0.00072 19.3 3.1 0.056 13.3 0.1 2.5 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain FATC PF02260.15 ETO03651.1 - 0.0027 17.1 0.2 1.3 8.5 0.0 2.2 2 0 0 2 2 2 2 FATC domain PPR PF01535.15 ETO03651.1 - 0.0044 16.9 0.6 3.1 7.9 0.0 2.3 2 0 0 2 2 2 2 PPR repeat Apc3 PF12895.2 ETO03651.1 - 0.0076 16.3 0.5 0.13 12.4 0.1 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.4 ETO03651.1 - 0.0078 15.6 0.1 0.48 9.7 0.0 2.0 2 0 0 2 2 2 1 26S proteasome subunit RPN7 DUF357 PF04010.8 ETO03651.1 - 0.027 14.1 0.7 3.1 7.5 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF357) HisG PF01634.13 ETO03651.1 - 0.028 14.0 0.1 5.2 6.6 0.0 2.0 1 1 1 2 2 2 0 ATP phosphoribosyltransferase DUF2225 PF09986.4 ETO03651.1 - 0.064 12.7 0.1 0.077 12.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) MinC_C PF03775.11 ETO03651.1 - 0.074 12.6 0.0 3.1 7.4 0.0 2.0 1 1 1 2 2 2 0 Septum formation inhibitor MinC, C-terminal domain DUF4438 PF14505.1 ETO03651.1 - 0.076 11.7 0.0 0.081 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4438) EssA PF10661.4 ETO03652.1 - 0.39 10.4 5.1 0.47 10.1 3.5 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA Sec62 PF03839.11 ETO03652.1 - 0.6 9.4 5.5 0.72 9.2 3.8 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 ubiquitin PF00240.18 ETO03653.1 - 0.0013 18.0 0.9 0.0028 16.9 0.0 2.1 3 0 0 3 3 3 1 Ubiquitin family MCLC PF05934.6 ETO03653.1 - 0.11 10.7 3.0 0.14 10.3 2.1 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) DUF4097 PF13349.1 ETO03653.1 - 0.25 10.8 8.1 0.046 13.2 3.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4097) ubiquitin PF00240.18 ETO03654.1 - 1.7e-45 152.2 9.2 3.9e-30 103.0 0.4 3.0 2 1 1 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.3 ETO03654.1 - 1.9e-21 75.5 4.4 2.1e-15 56.1 0.1 3.0 2 1 1 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 ETO03654.1 - 1.5e-08 34.7 2.1 1e-05 25.7 0.1 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain NdhM PF10664.4 ETO03654.1 - 0.0068 16.3 1.5 0.98 9.3 0.1 2.5 1 1 1 2 2 2 2 Cyanobacterial and plastid NDH-1 subunit M USP7_C2 PF14533.1 ETO03654.1 - 0.0069 15.8 1.1 0.64 9.4 0.0 2.1 1 1 1 2 2 2 2 Ubiquitin-specific protease C-terminal PI3K_rbd PF00794.13 ETO03654.1 - 0.0082 16.0 2.7 0.51 10.3 0.3 2.5 2 1 1 3 3 3 1 PI3-kinase family, ras-binding domain Telomere_Sde2 PF13019.1 ETO03654.1 - 0.015 15.0 0.3 0.46 10.1 0.0 2.5 2 1 1 3 3 3 0 Telomere stability and silencing FERM_N PF09379.5 ETO03654.1 - 0.03 14.3 1.5 7.4 6.6 0.1 2.9 2 1 0 2 2 2 0 FERM N-terminal domain eRF1_1 PF03463.10 ETO03654.1 - 0.035 13.6 0.2 5.7 6.5 0.0 2.2 2 0 0 2 2 2 0 eRF1 domain 1 DUF2870 PF11069.3 ETO03654.1 - 0.082 12.9 0.3 0.93 9.5 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 ETO03654.1 - 0.12 12.2 2.1 5.3 7.0 0.1 2.3 2 0 0 2 2 2 0 GLUT4 regulating protein TUG PGA2 PF07543.7 ETO03656.1 - 0.31 10.8 3.6 0.58 9.9 2.5 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 Lipase_3 PF01764.20 ETO03657.1 - 1.8e-13 50.3 0.0 3.1e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) H_PPase PF03030.11 ETO03658.1 - 0.076 11.2 1.1 0.1 10.8 0.8 1.1 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase OMP_b-brl PF13505.1 ETO03658.1 - 0.12 12.2 3.0 0.19 11.6 2.1 1.3 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain Lipoprotein_19 PF13617.1 ETO03658.1 - 4.2 7.0 8.5 15 5.3 5.9 2.0 1 0 0 1 1 1 0 YnbE-like lipoprotein DUF1777 PF08648.7 ETO03660.1 - 0.15 11.8 12.1 0.23 11.1 8.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 ETO03660.1 - 0.19 10.1 5.0 0.19 10.1 3.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2217 PF10265.4 ETO03660.1 - 0.41 9.3 13.9 0.49 9.1 9.7 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF572 PF04502.8 ETO03660.1 - 0.47 9.6 4.9 0.55 9.4 3.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF605 PF04652.11 ETO03660.1 - 1.5 8.1 6.3 2 7.7 4.4 1.1 1 0 0 1 1 1 0 Vta1 like DUF566 PF04484.7 ETO03660.1 - 1.6 8.1 18.6 1.9 7.8 12.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) NPR3 PF03666.8 ETO03660.1 - 1.7 7.0 6.3 2.3 6.6 4.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Peptidase_S64 PF08192.6 ETO03660.1 - 5 5.3 10.3 5.4 5.2 7.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 2OG-FeII_Oxy_3 PF13640.1 ETO03661.1 - 0.00031 21.2 0.1 0.065 13.7 0.0 2.7 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily Menin PF05053.8 ETO03661.1 - 0.32 9.1 3.7 0.54 8.3 2.6 1.3 1 0 0 1 1 1 0 Menin WD40 PF00400.27 ETO03662.1 - 1.5e-40 135.6 20.5 2.7e-12 46.0 0.5 6.5 6 2 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO03662.1 - 5.1e-06 24.8 0.9 0.027 12.6 0.1 3.1 2 1 2 4 4 4 2 Nucleoporin Nup120/160 DUF948 PF06103.6 ETO03662.1 - 0.3 10.9 1.6 0.59 10.0 1.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF2457 PF10446.4 ETO03663.1 - 3.8 6.1 12.2 4.2 6.0 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.5 ETO03663.1 - 6.5 7.0 11.4 8.4 6.6 7.9 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain MIT PF04212.13 ETO03665.1 - 0.016 15.0 0.7 0.027 14.3 0.5 1.3 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain CompInhib_SCIN PF11546.3 ETO03665.1 - 0.06 13.2 1.2 0.1 12.4 0.8 1.3 1 0 0 1 1 1 0 Staphylococcal complement inhibitor SCIN DUF745 PF05335.8 ETO03665.1 - 0.067 12.7 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF2457 PF10446.4 ETO03667.1 - 0.16 10.6 22.9 0.17 10.5 15.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF572 PF04502.8 ETO03667.1 - 0.27 10.4 15.0 0.27 10.4 10.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Lin-8 PF03353.10 ETO03667.1 - 1.5 8.0 17.4 1.5 7.9 12.0 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist FYDLN_acid PF09538.5 ETO03667.1 - 2 9.0 19.7 2.6 8.6 13.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CDK2AP PF09806.4 ETO03667.1 - 2.4 8.3 9.2 3 8.0 6.4 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein CENP-T PF15511.1 ETO03667.1 - 2.6 7.1 20.7 2.8 7.0 14.4 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T ORC6 PF05460.8 ETO03667.1 - 3.6 6.5 12.4 3.8 6.5 8.6 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PGA2 PF07543.7 ETO03667.1 - 5.4 6.8 12.9 6.4 6.5 8.9 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 Vfa1 PF08432.5 ETO03667.1 - 6.6 6.7 15.4 7.9 6.4 10.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1510 PF07423.6 ETO03667.1 - 6.9 5.9 24.4 7.4 5.8 16.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nop14 PF04147.7 ETO03667.1 - 8.2 4.1 29.7 8.1 4.2 20.6 1.0 1 0 0 1 1 1 0 Nop14-like family NACHT PF05729.7 ETO03668.1 - 5.1e-18 65.2 0.0 3e-16 59.5 0.0 3.0 2 1 0 2 2 2 1 NACHT domain HEAT_2 PF13646.1 ETO03668.1 - 3.3e-12 46.5 0.0 6.8e-05 23.0 0.0 4.4 3 0 0 3 3 3 3 HEAT repeats Ank_2 PF12796.2 ETO03668.1 - 2.9e-10 40.3 0.0 2.5e-09 37.3 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO03668.1 - 3.7e-10 39.0 0.0 5e-06 26.2 0.0 3.5 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.25 ETO03668.1 - 3e-09 36.2 0.1 3e-05 23.6 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 ETO03668.1 - 9.2e-09 35.2 0.6 8e-06 25.9 0.0 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO03668.1 - 1.9e-07 31.4 1.6 5e-07 30.0 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) HEAT PF02985.17 ETO03668.1 - 5.8e-07 29.0 0.0 0.13 12.4 0.0 4.9 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 ETO03668.1 - 0.0023 18.3 0.0 0.26 11.8 0.0 3.8 3 1 1 4 4 4 1 HEAT-like repeat AAA_16 PF13191.1 ETO03668.1 - 0.0063 16.5 0.0 0.037 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Toxin_35 PF10530.4 ETO03669.1 - 0.98 9.5 3.9 1.9 8.6 2.7 1.4 1 0 0 1 1 1 0 Toxin with inhibitor cystine knot ICK or Knottin scaffold DUF2893 PF11459.3 ETO03671.1 - 0.012 15.3 0.1 0.026 14.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknwon function (DUF2893) DUF3947 PF13135.1 ETO03672.1 - 0.056 13.6 2.5 0.17 12.1 1.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) FixO PF02433.10 ETO03672.1 - 0.14 11.4 4.0 0.24 10.7 2.8 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO Spore_II_R PF09551.5 ETO03672.1 - 9 6.3 9.8 1.3 9.0 2.8 2.0 1 1 1 2 2 2 0 Stage II sporulation protein R (spore_II_R) OmpH PF03938.9 ETO03673.1 - 0.22 11.4 7.4 0.32 10.9 5.1 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) GAGA_bind PF06217.7 ETO03673.1 - 1.1 9.1 6.3 1.5 8.7 4.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Sec62 PF03839.11 ETO03673.1 - 8.8 5.6 11.5 12 5.1 8.0 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 YesK PF14150.1 ETO03676.1 - 0.21 11.6 3.1 0.87 9.7 1.0 2.4 2 1 1 3 3 3 0 YesK-like protein PPR PF01535.15 ETO03677.1 - 3e-15 55.0 7.7 0.0059 16.5 0.0 5.8 7 0 0 7 7 7 4 PPR repeat PPR_2 PF13041.1 ETO03677.1 - 1.4e-14 53.7 7.4 3.6e-08 33.2 0.0 4.7 4 1 1 5 5 5 3 PPR repeat family PPR_3 PF13812.1 ETO03677.1 - 2.5e-13 49.1 0.0 0.002 18.2 0.0 5.3 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 ETO03677.1 - 4.1e-12 45.3 1.8 0.002 17.5 0.0 4.3 4 0 0 4 4 4 3 PPR repeat DUF3636 PF12331.3 ETO03677.1 - 0.035 13.6 0.1 0.056 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3636) Ctr PF04145.10 ETO03679.1 - 0.028 14.4 0.2 0.028 14.4 0.1 1.7 2 0 0 2 2 2 0 Ctr copper transporter family WD40 PF00400.27 ETO03680.1 - 6.7e-28 95.5 15.2 9.9e-13 47.4 0.1 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO03680.1 - 4.5e-07 28.3 0.3 0.0016 16.6 0.3 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Pox_TAP PF03355.9 ETO03680.1 - 0.025 13.9 1.3 0.034 13.5 0.9 1.1 1 0 0 1 1 1 0 Viral Trans-Activator Protein Kelch_6 PF13964.1 ETO03680.1 - 0.038 14.1 3.7 2 8.6 0.1 3.1 3 0 0 3 3 3 0 Kelch motif DUF3601 PF12208.3 ETO03680.1 - 0.042 13.7 0.1 0.16 11.9 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3601) Nucleoporin_N PF08801.6 ETO03680.1 - 0.078 11.7 1.7 2.8 6.5 0.3 2.5 1 1 2 3 3 3 0 Nup133 N terminal like PSI PF01437.20 ETO03680.1 - 0.13 12.4 3.7 0.13 12.4 1.4 2.0 2 1 0 2 2 2 0 Plexin repeat HEAT_2 PF13646.1 ETO03681.1 - 0.0017 18.6 0.0 0.0089 16.2 0.0 1.8 1 1 0 1 1 1 1 HEAT repeats Vac14_Fab1_bd PF12755.2 ETO03681.1 - 0.02 15.2 0.1 4.3 7.7 0.0 2.3 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 ETO03681.1 - 0.088 13.3 0.3 3.2 8.3 0.0 2.6 2 1 1 3 3 3 0 HEAT-like repeat HEAT PF02985.17 ETO03681.1 - 0.18 11.9 0.5 32 4.9 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat MepB PF08877.5 ETO03683.1 - 0.0063 16.0 0.1 0.0075 15.7 0.1 1.4 1 0 0 1 1 1 1 MepB protein DUF3883 PF13020.1 ETO03683.1 - 0.046 13.4 2.3 0.71 9.6 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3883) PEX-1N PF09262.6 ETO03683.1 - 0.21 11.6 0.9 0.53 10.3 0.4 1.9 1 1 1 2 2 2 0 Peroxisome biogenesis factor 1, N-terminal CytochromB561_N PF09786.4 ETO03687.1 - 1.3 7.3 13.3 1.6 7.0 9.2 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal Ribosomal_L6e PF01159.14 ETO03687.1 - 1.6 9.0 7.2 2.8 8.2 5.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L6e YqfQ PF14181.1 ETO03687.1 - 2.5 8.1 12.0 0.34 10.9 5.4 1.6 2 0 0 2 2 2 0 YqfQ-like protein Sec62 PF03839.11 ETO03687.1 - 7.3 5.9 9.4 11 5.3 6.5 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 TLD PF07534.11 ETO03688.1 - 1e-05 25.5 0.0 2.2e-05 24.4 0.0 1.5 2 0 0 2 2 2 1 TLD RRM_1 PF00076.17 ETO03689.1 - 1e-12 47.4 0.9 2.7e-10 39.7 0.2 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO03689.1 - 6.5e-08 32.4 0.2 1.9e-05 24.5 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO03689.1 - 0.00017 21.3 0.1 0.00035 20.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HPS3_C PF14763.1 ETO03690.1 - 0.0069 15.4 0.2 0.0071 15.3 0.1 1.2 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3, C-terminal Cu_bind_like PF02298.12 ETO03690.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Plastocyanin-like domain Pkinase PF00069.20 ETO03691.1 - 6.9e-17 61.4 0.0 8e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO03691.1 - 0.00085 18.4 0.0 0.001 18.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 ETO03692.1 - 1.4e-19 70.2 0.1 1.6e-19 70.0 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO03692.1 - 3e-11 42.9 0.2 3.6e-11 42.6 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase FliG_C PF01706.11 ETO03692.1 - 0.075 13.0 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 FliG C-terminal domain SR-25 PF10500.4 ETO03693.1 - 0.53 9.7 25.9 0.68 9.3 17.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2422 PF10337.4 ETO03693.1 - 0.81 8.4 6.9 0.91 8.2 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Zip PF02535.17 ETO03693.1 - 1.1 8.2 6.1 1.1 8.2 4.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF913 PF06025.7 ETO03693.1 - 1.4 7.5 11.6 1.6 7.3 8.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Secretin_N_2 PF07655.8 ETO03693.1 - 1.8 9.0 11.3 3 8.3 7.8 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain CDC45 PF02724.9 ETO03693.1 - 1.8 6.4 20.8 2.2 6.2 14.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S64 PF08192.6 ETO03693.1 - 4.2 5.5 17.3 4.8 5.3 12.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF1510 PF07423.6 ETO03693.1 - 4.5 6.5 25.1 6 6.1 17.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF262 PF03235.9 ETO03693.1 - 4.7 7.1 14.1 6.5 6.6 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 Cupin_8 PF13621.1 ETO03693.1 - 5.3 6.4 12.3 8.2 5.8 8.5 1.3 1 1 0 1 1 1 0 Cupin-like domain DUF2201_N PF13203.1 ETO03693.1 - 8.2 5.5 11.4 8.4 5.4 7.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain RP-C_C PF11800.3 ETO03693.1 - 8.9 5.9 12.2 12 5.5 8.4 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region RR_TM4-6 PF06459.7 ETO03693.1 - 9.1 6.0 18.4 11 5.8 12.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_11 PF13086.1 ETO03693.1 - 9.4 5.7 15.2 14 5.1 10.5 1.3 1 0 0 1 1 1 0 AAA domain Vfa1 PF08432.5 ETO03693.1 - 9.5 6.2 27.8 13 5.7 19.3 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 MIT PF04212.13 ETO03694.1 - 0.00036 20.3 1.4 0.00057 19.7 1.0 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain ADPrib_exo_Tox PF03496.9 ETO03694.1 - 0.054 12.7 0.1 0.067 12.4 0.1 1.2 1 0 0 1 1 1 0 ADP-ribosyltransferase exoenzyme V-SNARE PF05008.10 ETO03694.1 - 0.12 12.5 1.7 0.42 10.8 1.2 1.9 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus CBS PF00571.23 ETO03697.1 - 0.00016 21.4 0.0 0.00028 20.6 0.0 1.3 1 0 0 1 1 1 1 CBS domain OTCace PF00185.19 ETO03697.1 - 0.011 15.5 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Peptidase_C65 PF10275.4 ETO03697.1 - 0.036 13.4 4.3 0.72 9.1 0.1 2.0 1 1 1 2 2 2 0 Peptidase C65 Otubain Peroxin-3 PF04882.7 ETO03698.1 - 0.02 13.5 3.0 0.024 13.3 2.1 1.1 1 0 0 1 1 1 0 Peroxin-3 Borrelia_P83 PF05262.6 ETO03698.1 - 0.046 11.9 2.7 0.074 11.3 1.9 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4193 PF13834.1 ETO03698.1 - 1.7 8.8 6.8 3.3 7.9 4.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4193) DUF2457 PF10446.4 ETO03698.1 - 2.2 6.9 11.3 0.76 8.4 5.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) DUF2407_C PF13373.1 ETO03698.1 - 2.8 7.8 9.6 1.7 8.5 4.1 1.9 2 0 0 2 2 2 0 DUF2407 C-terminal domain PBD PF00786.23 ETO03698.1 - 6.6 7.2 8.5 5.3 7.5 1.3 2.5 2 0 0 2 2 2 0 P21-Rho-binding domain TSC22 PF01166.13 ETO03699.1 - 0.0021 17.9 13.5 0.0034 17.3 0.3 3.3 2 1 2 4 4 4 1 TSC-22/dip/bun family DUF4315 PF14193.1 ETO03699.1 - 0.21 11.5 0.2 0.21 11.5 0.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4315) Fzo_mitofusin PF04799.8 ETO03699.1 - 0.44 9.9 7.0 4.2 6.7 0.0 2.5 2 1 0 2 2 2 0 fzo-like conserved region ATG16 PF08614.6 ETO03699.1 - 0.64 9.8 15.1 7.8 6.2 0.1 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) FlxA PF14282.1 ETO03699.1 - 3.3 7.6 16.6 0.18 11.7 1.5 3.0 2 1 0 2 2 2 0 FlxA-like protein AAA_13 PF13166.1 ETO03699.1 - 4 5.7 13.1 1.1 7.6 3.6 1.8 1 1 0 1 1 1 0 AAA domain DivIC PF04977.10 ETO03699.1 - 5.4 6.5 14.3 6.5 6.3 0.8 3.3 3 0 0 3 3 3 0 Septum formation initiator BTV_NS2 PF04514.7 ETO03699.1 - 6.4 5.5 8.7 7 5.4 6.0 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 bZIP_1 PF00170.16 ETO03699.1 - 8 6.5 12.4 3.4 7.7 0.5 3.2 3 1 0 3 3 3 0 bZIP transcription factor CCDC92 PF14916.1 ETO03699.1 - 8.9 5.9 10.6 3.8 7.1 1.0 3.1 3 0 0 3 3 3 0 Coiled-coil domain of unknown function DUF2237 PF09996.4 ETO03700.1 - 0.048 13.1 0.0 0.069 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2237) PDZ PF00595.19 ETO03701.1 - 0.0026 17.8 0.2 0.0061 16.7 0.2 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Arf PF00025.16 ETO03702.1 - 2.3e-67 225.6 0.2 7.4e-67 223.9 0.2 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 ETO03702.1 - 3e-11 42.8 0.0 4.9e-11 42.1 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 ETO03702.1 - 1.6e-09 36.9 0.5 3.6e-07 29.2 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 ETO03702.1 - 1.6e-09 37.3 0.0 2.1e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO03702.1 - 1.9e-07 31.5 0.0 3.4e-07 30.7 0.0 1.4 1 1 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 ETO03702.1 - 2.2e-05 23.7 0.0 2.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 ETO03702.1 - 0.00037 20.4 0.1 0.0007 19.5 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.7 ETO03702.1 - 0.00097 18.8 0.2 0.0017 18.0 0.2 1.5 1 1 0 1 1 1 1 NACHT domain Thioredoxin_2 PF13098.1 ETO03702.1 - 0.1 12.7 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain AAA_33 PF13671.1 ETO03702.1 - 0.12 12.2 0.1 0.32 10.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain Haem_bd PF14376.1 ETO03703.1 - 3.8 7.1 7.5 0.43 10.2 0.1 2.3 2 0 0 2 2 2 0 Haem-binding domain ERF PF04404.7 ETO03703.1 - 6.5 6.2 12.9 26 4.3 0.0 2.7 3 0 0 3 3 3 0 ERF superfamily DUF1664 PF07889.7 ETO03705.1 - 0.00023 20.9 5.9 0.0003 20.5 4.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) HAP1_N PF04849.8 ETO03705.1 - 0.0005 19.1 13.5 0.00058 18.9 9.3 1.0 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DUF812 PF05667.6 ETO03705.1 - 0.00053 18.6 11.7 0.00065 18.3 8.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) HALZ PF02183.13 ETO03705.1 - 0.00059 19.4 3.7 0.00059 19.4 2.6 2.6 1 1 1 2 2 2 1 Homeobox associated leucine zipper TBPIP PF07106.8 ETO03705.1 - 0.00098 18.7 12.5 0.0013 18.3 8.7 1.2 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Jnk-SapK_ap_N PF09744.4 ETO03705.1 - 0.0025 17.8 7.2 0.0025 17.8 5.0 2.0 1 1 1 2 2 2 1 JNK_SAPK-associated protein-1 GAS PF13851.1 ETO03705.1 - 0.0025 17.0 15.0 0.0032 16.6 10.4 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding FliD_C PF07195.7 ETO03705.1 - 0.0032 16.8 4.7 0.0032 16.8 3.2 2.0 1 1 1 2 2 2 1 Flagellar hook-associated protein 2 C-terminus DUF4515 PF14988.1 ETO03705.1 - 0.0038 16.9 18.9 0.0061 16.2 13.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4515) Vps5 PF09325.5 ETO03705.1 - 0.0043 16.3 10.3 0.0061 15.8 1.0 2.0 1 1 1 2 2 2 1 Vps5 C terminal like Rab5-bind PF09311.6 ETO03705.1 - 0.0044 16.9 15.1 0.0066 16.3 10.5 1.3 1 0 0 1 1 1 1 Rabaptin-like protein HOOK PF05622.7 ETO03705.1 - 0.0045 14.8 12.6 0.0071 14.2 8.7 1.3 1 0 0 1 1 1 1 HOOK protein DUF342 PF03961.8 ETO03705.1 - 0.0048 15.3 10.0 0.0057 15.1 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF342) ADIP PF11559.3 ETO03705.1 - 0.0069 16.3 21.1 0.21 11.5 5.7 2.0 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.3 ETO03705.1 - 0.0073 16.0 22.0 0.016 15.0 5.5 2.4 1 1 1 2 2 2 1 TATA element modulatory factor 1 DNA binding DUF816 PF05674.7 ETO03705.1 - 0.0074 16.0 2.9 0.0088 15.7 2.0 1.3 1 1 0 1 1 1 1 Baculovirus protein of unknown function (DUF816) Atg14 PF10186.4 ETO03705.1 - 0.01 14.8 10.5 0.015 14.2 7.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Geminin PF07412.7 ETO03705.1 - 0.011 15.4 12.3 0.041 13.5 2.4 2.1 1 1 1 2 2 2 0 Geminin DUF2935 PF11155.3 ETO03705.1 - 0.011 15.8 7.1 0.013 15.5 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) Reo_sigmaC PF04582.7 ETO03705.1 - 0.011 14.9 1.1 0.013 14.7 0.8 1.0 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Striatin PF08232.7 ETO03705.1 - 0.014 15.7 9.2 0.018 15.3 6.4 1.1 1 0 0 1 1 1 0 Striatin family DivIC PF04977.10 ETO03705.1 - 0.015 14.7 4.5 0.015 14.7 3.1 2.8 1 1 1 2 2 2 0 Septum formation initiator DUF2317 PF10079.4 ETO03705.1 - 0.016 13.8 6.8 0.017 13.7 4.7 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Bacillus_HBL PF05791.6 ETO03705.1 - 0.018 14.4 9.4 0.021 14.1 6.5 1.1 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) CENP-F_leu_zip PF10473.4 ETO03705.1 - 0.019 14.8 15.9 0.022 14.5 11.0 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc24 PF08286.6 ETO03705.1 - 0.021 14.5 19.2 0.08 12.6 3.3 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF3584 PF12128.3 ETO03705.1 - 0.026 11.8 11.0 0.032 11.5 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.6 ETO03705.1 - 0.029 13.0 14.8 0.037 12.6 10.3 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein FlxA PF14282.1 ETO03705.1 - 0.03 14.2 20.4 0.054 13.4 14.1 1.3 1 0 0 1 1 1 0 FlxA-like protein DUF4200 PF13863.1 ETO03705.1 - 0.031 14.2 21.4 0.37 10.7 4.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Filament PF00038.16 ETO03705.1 - 0.042 13.3 13.7 0.058 12.8 9.5 1.2 1 0 0 1 1 1 0 Intermediate filament protein Herpes_BLRF2 PF05812.7 ETO03705.1 - 0.049 13.4 11.2 0.07 12.9 7.2 1.7 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein TPR_MLP1_2 PF07926.7 ETO03705.1 - 0.053 13.2 20.0 6.8 6.4 2.8 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.1 ETO03705.1 - 0.054 11.9 12.1 0.066 11.6 8.4 1.0 1 0 0 1 1 1 0 AAA domain DUF948 PF06103.6 ETO03705.1 - 0.055 13.3 9.4 0.031 14.1 3.7 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) EzrA PF06160.7 ETO03705.1 - 0.062 11.4 13.4 0.09 10.9 9.3 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA APG6 PF04111.7 ETO03705.1 - 0.064 12.3 15.0 0.096 11.7 10.4 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 RmuC PF02646.11 ETO03705.1 - 0.064 12.0 10.3 0.078 11.8 7.1 1.1 1 0 0 1 1 1 0 RmuC family Baculo_PEP_C PF04513.7 ETO03705.1 - 0.069 12.9 3.6 0.11 12.3 2.5 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus RTBV_P46 PF06216.6 ETO03705.1 - 0.08 11.7 7.7 0.23 10.2 5.4 1.8 1 1 0 1 1 1 0 Rice tungro bacilliform virus P46 protein DUF4140 PF13600.1 ETO03705.1 - 0.1 13.0 11.6 0.16 12.4 1.2 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) V_ATPase_I PF01496.14 ETO03705.1 - 0.11 10.3 10.1 0.15 9.8 7.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Muted PF14942.1 ETO03705.1 - 0.11 12.3 10.6 0.17 11.7 7.3 1.3 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Lebercilin PF15619.1 ETO03705.1 - 0.13 11.6 16.4 0.21 10.9 11.4 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Lectin_N PF03954.9 ETO03705.1 - 0.15 11.4 8.1 0.36 10.2 3.4 2.0 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Transposase_22 PF02994.9 ETO03705.1 - 0.15 10.5 10.3 0.19 10.1 7.1 1.0 1 0 0 1 1 1 0 L1 transposable element bZIP_1 PF00170.16 ETO03705.1 - 0.15 12.0 16.7 0.059 13.3 7.0 2.5 1 1 1 2 2 2 0 bZIP transcription factor ATG16 PF08614.6 ETO03705.1 - 0.16 11.7 18.2 0.63 9.8 12.6 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4250 PF14056.1 ETO03705.1 - 0.17 11.6 4.1 0.14 11.9 1.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4250) DUF3450 PF11932.3 ETO03705.1 - 0.18 11.0 10.8 0.24 10.6 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF489 PF04356.7 ETO03705.1 - 0.19 11.3 7.9 0.29 10.6 5.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF489) Laminin_II PF06009.7 ETO03705.1 - 0.19 11.4 11.0 0.25 11.0 7.6 1.1 1 0 0 1 1 1 0 Laminin Domain II Tho2 PF11262.3 ETO03705.1 - 0.2 10.6 9.1 0.26 10.2 6.3 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 AbiH PF14253.1 ETO03705.1 - 0.22 11.0 7.7 0.24 10.9 5.3 1.0 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH Viral_P18 PF04521.8 ETO03705.1 - 0.25 10.7 11.8 1.2 8.5 1.1 2.1 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein TBCA PF02970.11 ETO03705.1 - 0.26 11.4 15.4 1.2 9.2 8.2 2.0 1 1 1 2 2 2 0 Tubulin binding cofactor A CCDC144C PF14915.1 ETO03705.1 - 0.27 10.1 19.2 0.22 10.4 2.2 1.6 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region BLOC1_2 PF10046.4 ETO03705.1 - 0.27 11.3 15.1 0.13 12.3 5.8 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 ETO03705.1 - 0.29 10.6 20.7 0.94 9.0 14.3 1.7 1 1 0 1 1 1 0 IncA protein DUF4446 PF14584.1 ETO03705.1 - 0.29 10.9 11.8 0.82 9.4 2.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF972 PF06156.8 ETO03705.1 - 0.31 11.4 15.5 6 7.2 10.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Mnd1 PF03962.10 ETO03705.1 - 0.32 10.6 16.7 0.54 9.8 11.5 1.3 1 1 0 1 1 1 0 Mnd1 family FemAB PF02388.11 ETO03705.1 - 0.32 9.6 9.3 0.35 9.4 6.4 1.1 1 0 0 1 1 1 0 FemAB family HXXSHH PF07586.6 ETO03705.1 - 0.4 9.5 3.1 0.45 9.3 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) HrpB7 PF09486.5 ETO03705.1 - 0.41 10.5 8.0 1.6 8.6 1.8 2.0 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) rve_3 PF13683.1 ETO03705.1 - 0.43 10.1 2.2 2.6 7.6 0.2 2.4 1 1 1 2 2 2 0 Integrase core domain Tweety PF04906.8 ETO03705.1 - 0.43 8.9 3.6 0.46 8.8 2.5 1.1 1 0 0 1 1 1 0 Tweety Fib_alpha PF08702.5 ETO03705.1 - 0.47 10.5 14.9 1.8 8.6 10.3 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family WXG100 PF06013.7 ETO03705.1 - 0.47 10.4 6.6 1.7 8.7 4.3 2.0 1 1 0 1 1 1 0 Proteins of 100 residues with WXG Phage_GPO PF05929.6 ETO03705.1 - 0.49 9.5 7.9 0.61 9.2 5.5 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Kinetocho_Slk19 PF12709.2 ETO03705.1 - 0.53 10.4 15.2 0.92 9.6 2.6 2.5 1 1 1 2 2 2 0 Central kinetochore-associated Exonuc_VII_L PF02601.10 ETO03705.1 - 0.53 9.4 9.9 0.64 9.1 6.9 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Prefoldin PF02996.12 ETO03705.1 - 0.55 9.9 15.8 0.67 9.6 2.8 2.2 1 1 1 2 2 2 0 Prefoldin subunit AAA_32 PF13654.1 ETO03705.1 - 0.71 8.4 11.2 0.74 8.4 7.8 1.0 1 0 0 1 1 1 0 AAA domain TSC22 PF01166.13 ETO03705.1 - 0.74 9.8 10.7 0.063 13.2 2.6 2.3 1 1 1 2 2 2 0 TSC-22/dip/bun family FadA PF09403.5 ETO03705.1 - 0.78 9.7 12.1 0.058 13.4 4.2 1.8 1 1 1 2 2 2 0 Adhesion protein FadA Tropomyosin_1 PF12718.2 ETO03705.1 - 0.82 9.5 21.7 1.9 8.3 15.0 1.5 1 1 0 1 1 1 0 Tropomyosin like OmpH PF03938.9 ETO03705.1 - 0.83 9.5 16.0 1.2 8.9 11.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3573 PF12097.3 ETO03705.1 - 0.84 8.1 7.4 1.2 7.7 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Tmemb_cc2 PF10267.4 ETO03705.1 - 0.86 8.1 15.2 6.2 5.2 10.8 1.8 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein ABC_membrane_3 PF13748.1 ETO03705.1 - 0.89 8.5 4.3 0.58 9.1 1.0 1.8 1 1 1 2 2 2 0 ABC transporter transmembrane region DUF16 PF01519.11 ETO03705.1 - 0.91 9.7 17.1 2.4 8.4 11.8 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 Ax_dynein_light PF10211.4 ETO03705.1 - 0.94 9.2 17.3 1.6 8.5 10.6 1.9 1 1 1 2 2 2 0 Axonemal dynein light chain Allexi_40kDa PF05549.6 ETO03705.1 - 0.96 8.6 5.1 1.2 8.4 3.5 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF3552 PF12072.3 ETO03705.1 - 0.98 8.5 20.9 0.57 9.3 5.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Med9 PF07544.8 ETO03705.1 - 1.1 9.0 13.6 1.2 8.8 7.6 2.1 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Phage_GP20 PF06810.6 ETO03705.1 - 1.1 8.6 19.7 0.35 10.2 9.8 1.9 1 1 1 2 2 2 0 Phage minor structural protein GP20 Fzo_mitofusin PF04799.8 ETO03705.1 - 1.4 8.2 13.1 0.31 10.3 1.9 2.0 1 1 1 2 2 2 0 fzo-like conserved region DivIVA PF05103.8 ETO03705.1 - 1.4 8.9 18.4 2.4e+02 1.7 12.8 2.2 1 1 0 1 1 1 0 DivIVA protein FbpA PF05833.6 ETO03705.1 - 1.6 7.1 16.5 0.3 9.5 7.5 1.9 1 1 1 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) M_domain PF12938.2 ETO03705.1 - 1.7 8.4 6.4 2.1 8.0 4.4 1.2 1 0 0 1 1 1 0 M domain of GW182 PspA_IM30 PF04012.7 ETO03705.1 - 1.8 7.8 18.3 23 4.2 12.7 1.8 1 1 0 1 1 1 0 PspA/IM30 family DUF904 PF06005.7 ETO03705.1 - 1.8 8.8 24.8 4.8e+03 -2.1 17.2 2.4 1 1 0 1 1 0 0 Protein of unknown function (DUF904) FlaC_arch PF05377.6 ETO03705.1 - 1.9 8.4 13.3 5.6e+02 0.5 9.2 2.6 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) Sec2p PF06428.6 ETO03705.1 - 2 8.3 19.4 1.2e+03 -0.6 13.6 2.1 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p NPV_P10 PF05531.7 ETO03705.1 - 2.1 8.6 9.4 20 5.5 6.5 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein TMF_TATA_bd PF12325.3 ETO03705.1 - 2.1 8.0 17.9 17 5.1 12.5 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding eIF-4B PF06273.6 ETO03705.1 - 2.5 6.7 4.9 3.5 6.2 3.4 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B DASH_Dam1 PF08653.5 ETO03705.1 - 2.7 7.8 4.4 11 5.8 0.1 2.5 1 1 1 2 2 2 0 DASH complex subunit Dam1 ORF6C PF10552.4 ETO03705.1 - 2.7 7.7 14.7 5.4 6.7 3.3 2.1 1 1 1 2 2 2 0 ORF6C domain TMPIT PF07851.8 ETO03705.1 - 2.8 6.9 11.0 3.3 6.7 7.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.1 ETO03705.1 - 3.2 6.6 9.7 5.1 5.9 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_Maf PF03131.12 ETO03705.1 - 3.4 8.0 15.9 0.71 10.2 2.2 2.4 1 1 2 3 3 3 0 bZIP Maf transcription factor DUF2205 PF10224.4 ETO03705.1 - 3.4 7.2 13.1 5.1 6.7 1.8 2.4 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) Syntaxin-6_N PF09177.6 ETO03705.1 - 3.5 8.0 9.7 2.2 8.7 3.5 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Tup_N PF08581.5 ETO03705.1 - 3.7 7.8 14.9 0.22 11.7 3.7 2.3 1 1 1 2 2 2 0 Tup N-terminal Kinesin-relat_1 PF12711.2 ETO03705.1 - 3.8 7.9 14.3 2.9 8.3 8.2 1.9 1 1 1 2 2 2 0 Kinesin motor YlqD PF11068.3 ETO03705.1 - 3.8 7.5 18.9 19 5.2 13.2 1.8 1 1 0 1 1 1 0 YlqD protein YlbD_coat PF14071.1 ETO03705.1 - 3.9 7.5 10.7 13 5.8 7.5 1.8 1 1 0 1 1 1 0 Putative coat protein GrpE PF01025.14 ETO03705.1 - 4 6.9 14.5 10 5.6 10.0 1.5 1 1 0 1 1 1 0 GrpE MSG PF02349.10 ETO03705.1 - 4.3 7.3 9.6 6.7 6.7 6.7 1.3 1 0 0 1 1 1 0 Major surface glycoprotein Sec62 PF03839.11 ETO03705.1 - 4.5 6.6 8.8 5.6 6.3 6.1 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 Pox_A_type_inc PF04508.7 ETO03705.1 - 4.8 7.2 6.2 14 5.7 0.7 3.1 2 1 0 3 3 2 0 Viral A-type inclusion protein repeat MerR-DNA-bind PF09278.6 ETO03705.1 - 4.8 7.6 10.4 15 6.0 0.2 2.5 1 1 1 2 2 2 0 MerR, DNA binding FliT PF05400.8 ETO03705.1 - 5.1 7.5 14.5 25 5.3 7.1 2.1 1 1 1 2 2 2 0 Flagellar protein FliT End3 PF12761.2 ETO03705.1 - 5.4 6.5 14.7 6.7 6.2 10.2 1.1 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF641 PF04859.7 ETO03705.1 - 5.5 6.7 13.3 26 4.5 9.2 1.8 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) UPF0449 PF15136.1 ETO03705.1 - 5.6 7.2 12.0 0.58 10.3 0.9 2.2 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 Glutaredoxin2_C PF04399.8 ETO03705.1 - 5.7 6.5 8.8 6.6 6.3 3.7 1.9 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain Cluap1 PF10234.4 ETO03705.1 - 6.4 5.8 16.7 3.4 6.8 7.5 1.9 1 1 1 2 2 2 0 Clusterin-associated protein-1 CASP_C PF08172.7 ETO03705.1 - 7.4 5.5 15.4 1.5 7.8 2.9 2.0 1 1 1 2 2 2 0 CASP C terminal LMBR1 PF04791.11 ETO03705.1 - 7.7 4.9 6.0 9.2 4.7 4.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein ACCA PF03255.9 ETO03705.1 - 9.2 5.8 8.3 12 5.3 4.7 1.8 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit B56 PF01603.15 ETO03706.1 - 7.4e-34 117.0 0.6 8.1e-34 116.9 0.4 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) PAP_central PF04928.12 ETO03706.1 - 0.048 12.4 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 Poly(A) polymerase central domain Katanin_con80 PF13925.1 ETO03706.1 - 0.11 12.2 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 con80 domain of Katanin RICTOR_M PF14666.1 ETO03707.1 - 3.5e-05 22.9 0.3 4.9e-05 22.4 0.2 1.3 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, middle domain NST1 PF13945.1 ETO03707.1 - 1.4 8.9 6.8 5.8 6.9 4.8 1.8 1 1 1 2 2 2 0 Salt tolerance down-regulator Aldedh PF00171.17 ETO03708.1 - 1e-24 86.7 0.0 1.1e-24 86.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Homeobox_KN PF05920.6 ETO03709.1 - 4.3e-14 51.9 0.2 7.7e-14 51.1 0.1 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 ETO03709.1 - 6.2e-09 35.3 0.7 1.1e-08 34.5 0.5 1.4 1 0 0 1 1 1 1 Homeobox domain RhoGEF PF00621.15 ETO03710.1 - 0.01 15.7 1.3 0.075 12.8 0.9 1.9 1 1 0 1 1 1 0 RhoGEF domain U1snRNP70_N PF12220.3 ETO03710.1 - 2.5 8.4 4.5 5.7 7.3 2.0 2.0 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal YMF19 PF02326.10 ETO03712.1 - 0.04 14.4 1.4 0.081 13.5 1.0 1.6 1 0 0 1 1 1 0 Plant ATP synthase F0 Fungal_trans_2 PF11951.3 ETO03713.1 - 0.0094 14.5 0.2 0.0096 14.5 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF572 PF04502.8 ETO03714.1 - 8.1e-45 153.4 18.1 1.1e-44 153.0 12.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) DZR PF12773.2 ETO03714.1 - 0.036 13.8 4.2 14 5.5 0.0 3.2 3 0 0 3 3 3 0 Double zinc ribbon RNA_pol_N PF01194.12 ETO03714.1 - 0.32 11.0 0.1 0.32 11.0 0.1 3.4 3 2 0 3 3 3 0 RNA polymerases N / 8 kDa subunit zf-UBP PF02148.14 ETO03714.1 - 0.5 10.5 5.4 3.3 7.9 1.0 3.2 2 1 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein zinc_ribbon_2 PF13240.1 ETO03714.1 - 1.3 8.5 6.2 0.55 9.7 0.3 2.7 2 1 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 ETO03715.1 - 0.049 13.3 0.1 0.12 12.0 0.1 1.7 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 ETO03715.1 - 0.054 13.0 0.1 0.14 11.7 0.1 1.7 1 0 0 1 1 1 0 zinc-ribbon domain PH PF00169.24 ETO03716.1 - 1.8e-06 28.1 0.1 2.4e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 ETO03716.1 - 0.0063 16.7 0.6 0.017 15.3 0.4 1.7 1 1 0 1 1 1 1 Pleckstrin homology domain Mcp5_PH PF12814.2 ETO03716.1 - 0.036 13.9 0.1 0.11 12.4 0.0 1.8 1 1 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology PH_2 PF08458.5 ETO03716.1 - 0.058 13.3 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 Plant pleckstrin homology-like region NAC PF01849.13 ETO03718.1 - 0.63 9.6 4.8 0.17 11.3 0.3 2.3 2 0 0 2 2 2 0 NAC domain zf-primase PF09329.6 ETO03719.1 - 6.1e-07 28.9 0.6 1.6e-06 27.5 0.4 1.8 1 0 0 1 1 1 1 Primase zinc finger Pkinase PF00069.20 ETO03720.1 - 2.1e-41 141.7 0.0 2.3e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO03720.1 - 9.9e-21 73.9 0.0 1.1e-20 73.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO03720.1 - 0.00015 20.8 0.0 0.00018 20.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 ETO03720.1 - 0.086 12.1 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase PF00069.20 ETO03721.1 - 4.1e-21 75.3 0.1 4.6e-21 75.1 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO03721.1 - 1.2e-11 44.1 0.1 1.4e-11 43.9 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase ABC2_membrane_3 PF12698.2 ETO03723.1 - 8.7e-27 94.0 19.7 1e-26 93.8 13.7 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF1109 PF06532.6 ETO03723.1 - 0.65 9.3 5.8 0.12 11.7 1.7 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1109) DUF3397 PF11877.3 ETO03723.1 - 0.67 9.9 11.2 0.45 10.5 5.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3397) ABC2_membrane_2 PF12679.2 ETO03723.1 - 2.5 6.8 19.1 3.9 6.2 13.2 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein PgaD PF13994.1 ETO03723.1 - 8.4 5.8 9.6 0.55 9.7 0.4 2.7 1 1 3 4 4 4 0 PgaD-like protein DUF1514 PF07438.6 ETO03723.1 - 9.4 6.2 7.4 0.64 9.9 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1514) V-SNARE_C PF12352.3 ETO03725.1 - 2.2e-09 37.2 2.4 3.2e-09 36.7 1.6 1.3 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 ETO03725.1 - 4.3e-07 29.5 0.4 5.9e-07 29.1 0.2 1.2 1 0 0 1 1 1 1 Sec20 Laminin_II PF06009.7 ETO03725.1 - 0.0064 16.2 0.8 0.0098 15.6 0.6 1.3 1 0 0 1 1 1 1 Laminin Domain II EMP24_GP25L PF01105.19 ETO03725.1 - 0.0071 16.0 0.6 0.0093 15.6 0.4 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SNARE PF05739.14 ETO03725.1 - 0.023 14.3 2.8 0.039 13.6 1.9 1.4 1 0 0 1 1 1 0 SNARE domain Use1 PF09753.4 ETO03725.1 - 0.06 12.7 5.4 0.071 12.5 3.8 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 DEAD PF00270.24 ETO03725.1 - 0.064 12.7 0.5 0.072 12.5 0.4 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase Tetraspannin PF00335.15 ETO03725.1 - 0.066 12.4 0.3 0.097 11.9 0.2 1.3 1 0 0 1 1 1 0 Tetraspanin family Herpes_US9 PF06072.6 ETO03725.1 - 0.086 12.6 0.7 0.086 12.6 0.5 2.6 2 1 1 3 3 3 0 Alphaherpesvirus tegument protein US9 NPV_P10 PF05531.7 ETO03725.1 - 0.095 12.9 1.6 0.16 12.2 1.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Sec2p PF06428.6 ETO03725.1 - 0.33 10.8 6.2 0.43 10.4 4.3 1.2 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF883 PF05957.8 ETO03725.1 - 0.4 11.1 5.3 0.34 11.3 2.8 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF3287 PF11690.3 ETO03725.1 - 0.47 10.5 2.3 0.62 10.1 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) Uds1 PF15456.1 ETO03725.1 - 0.65 10.0 6.2 2.5 8.0 4.3 1.8 1 1 0 1 1 1 0 Up-regulated During Septation Cauli_AT PF03233.8 ETO03725.1 - 1 9.0 9.9 1.4 8.6 6.8 1.2 1 0 0 1 1 1 0 Aphid transmission protein CENP-K PF11802.3 ETO03725.1 - 1.1 8.3 7.7 1.4 8.1 5.3 1.1 1 0 0 1 1 1 0 Centromere-associated protein K TMPIT PF07851.8 ETO03725.1 - 1.2 8.0 3.8 1.6 7.7 2.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4559 PF15112.1 ETO03725.1 - 2.2 7.3 7.0 2.6 7.1 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DUF16 PF01519.11 ETO03725.1 - 3 8.0 8.7 5.2 7.3 6.0 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 Synaptobrevin PF00957.16 ETO03725.1 - 3.5 7.3 7.9 9.5 5.9 5.4 1.8 1 1 0 1 1 1 0 Synaptobrevin YtxH PF12732.2 ETO03725.1 - 5.5 7.4 9.1 0.52 10.7 3.0 1.8 1 1 1 2 2 2 0 YtxH-like protein HECT PF00632.20 ETO03726.1 - 9.9e-21 74.2 0.1 1.1e-20 73.9 0.1 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ras PF00071.17 ETO03727.1 - 1.4e-28 99.3 1.2 2.9e-28 98.2 0.8 1.5 1 1 0 1 1 1 1 Ras family Miro PF08477.8 ETO03727.1 - 1.4e-07 31.9 0.0 2.5e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO03727.1 - 0.00054 19.2 0.1 0.0028 16.9 0.1 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family NOA36 PF06524.7 ETO03727.1 - 0.6 9.3 3.7 0.71 9.0 2.5 1.2 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.4 ETO03727.1 - 0.67 8.6 8.1 0.81 8.3 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RGS PF00615.14 ETO03728.1 - 0.031 14.3 0.1 0.048 13.7 0.1 1.3 1 0 0 1 1 1 0 Regulator of G protein signaling domain Pkinase PF00069.20 ETO03729.1 - 4.1e-14 52.3 0.0 4.7e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO03729.1 - 0.047 12.7 0.0 0.053 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase RecO_N_2 PF13114.1 ETO03729.1 - 0.076 12.7 0.0 0.69 9.6 0.0 2.0 1 1 1 2 2 2 0 RecO N terminal Zip PF02535.17 ETO03730.1 - 8.2e-05 21.7 8.6 9.4e-05 21.5 6.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Shisa PF13908.1 ETO03730.1 - 0.012 15.7 0.3 0.017 15.3 0.2 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF929 PF06053.6 ETO03730.1 - 0.031 13.3 0.1 0.041 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF929) SelP_N PF04592.9 ETO03730.1 - 0.05 12.9 14.1 0.054 12.8 9.8 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Macoilin PF09726.4 ETO03730.1 - 0.055 11.7 7.4 0.06 11.6 5.1 1.1 1 0 0 1 1 1 0 Transmembrane protein BNIP3 PF06553.7 ETO03730.1 - 0.19 11.1 3.8 0.22 10.8 2.6 1.1 1 0 0 1 1 1 0 BNIP3 NicO PF03824.11 ETO03730.1 - 0.25 10.6 6.8 0.31 10.3 4.7 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein Innate_immun PF12782.2 ETO03730.1 - 0.55 9.4 13.7 0.55 9.4 9.5 1.2 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family WD40 PF00400.27 ETO03731.1 - 2.8e-05 23.8 0.5 0.032 14.1 0.1 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF3132 PF11330.3 ETO03731.1 - 0.072 12.9 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3132) COX5B PF01215.14 ETO03731.1 - 0.12 12.0 0.9 2.6 7.7 0.1 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase subunit Vb LsmAD PF06741.8 ETO03732.1 - 0.0015 18.5 0.8 0.074 13.1 0.5 2.1 2 0 0 2 2 2 2 LsmAD domain DUF3627 PF12299.3 ETO03733.1 - 0.072 13.1 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3627) DUF3340 PF11818.3 ETO03734.1 - 0.013 15.4 5.0 0.019 14.9 3.4 1.2 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) ubiquitin PF00240.18 ETO03739.1 - 8e-13 47.5 4.6 7.4e-12 44.4 3.2 2.1 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 ETO03739.1 - 1.5e-06 27.7 3.2 4.9e-06 26.1 2.2 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 ETO03739.1 - 3.7e-05 23.8 1.8 4.4e-05 23.5 1.2 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 ETO03739.1 - 0.0026 17.6 1.6 0.0039 17.0 1.1 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Angiomotin_C PF12240.3 ETO03739.1 - 0.046 13.2 1.4 0.051 13.0 0.9 1.2 1 0 0 1 1 1 0 Angiomotin C terminal Mucin PF01456.12 ETO03739.1 - 0.079 12.7 13.0 0.091 12.5 9.0 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Selenoprotein_S PF06936.6 ETO03739.1 - 0.1 12.0 0.8 0.1 12.0 0.5 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) p450 PF00067.17 ETO03739.1 - 0.37 9.2 4.4 0.37 9.2 3.1 1.1 1 0 0 1 1 1 0 Cytochrome P450 FH2 PF02181.18 ETO03740.1 - 7.5e-12 44.8 0.4 8.6e-12 44.6 0.2 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain THUMP PF02926.12 ETO03740.1 - 0.059 13.2 0.0 0.079 12.8 0.0 1.3 1 0 0 1 1 1 0 THUMP domain FAM176 PF14851.1 ETO03741.1 - 0.0072 16.0 10.4 0.0072 16.0 7.2 1.5 1 1 0 1 1 1 1 FAM176 family DUF4065 PF13274.1 ETO03741.1 - 0.0081 16.8 5.7 0.013 16.1 4.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4065) Rho_N PF07498.7 ETO03741.1 - 0.025 14.3 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain FLO_LFY PF01698.11 ETO03741.1 - 0.049 12.4 6.2 0.049 12.4 4.3 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF2796 PF10986.3 ETO03741.1 - 0.089 12.7 5.9 0.13 12.2 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Vfa1 PF08432.5 ETO03741.1 - 0.26 11.2 10.2 0.29 11.1 7.1 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TFIIF_alpha PF05793.7 ETO03741.1 - 0.79 8.0 25.2 0.97 7.7 17.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF506 PF04720.7 ETO03741.1 - 2.2 7.8 10.8 3.2 7.3 7.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF506) DUF1510 PF07423.6 ETO03741.1 - 2.8 7.2 18.6 3.6 6.8 12.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nop14 PF04147.7 ETO03741.1 - 2.9 5.7 22.9 2.8 5.7 15.9 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 ETO03741.1 - 3.8 6.4 18.1 3.6 6.5 12.5 1.1 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.6 ETO03741.1 - 4.4 5.2 17.8 5.5 4.9 12.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Daxx PF03344.10 ETO03741.1 - 5.3 5.3 20.4 5.3 5.4 14.2 1.1 1 0 0 1 1 1 0 Daxx Family Viral_Rep PF02407.11 ETO03742.1 - 0.081 12.9 0.0 0.11 12.5 0.0 1.3 1 1 0 1 1 1 0 Putative viral replication protein NIF PF03031.13 ETO03744.1 - 2.4e-05 24.0 0.1 3.8e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF2608 PF11019.3 ETO03744.1 - 0.063 12.2 0.0 0.071 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) DUF4302 PF14135.1 ETO03746.1 - 0.033 13.5 2.5 0.043 13.1 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4302) APG6 PF04111.7 ETO03746.1 - 0.045 12.8 19.6 0.054 12.5 13.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Transposase_22 PF02994.9 ETO03746.1 - 0.12 10.8 14.2 0.14 10.6 9.9 1.0 1 0 0 1 1 1 0 L1 transposable element CENP-F_leu_zip PF10473.4 ETO03746.1 - 0.16 11.8 26.5 0.11 12.3 17.3 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4201 PF13870.1 ETO03746.1 - 0.16 11.4 22.9 0.025 14.0 4.2 3.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) Atg14 PF10186.4 ETO03746.1 - 0.26 10.1 23.5 0.34 9.8 16.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4559 PF15112.1 ETO03746.1 - 0.31 10.1 16.4 0.36 9.9 11.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DivIVA PF05103.8 ETO03746.1 - 0.44 10.6 19.9 0.64 10.0 1.6 2.6 1 1 1 2 2 2 0 DivIVA protein SPAM PF02090.10 ETO03746.1 - 0.69 9.8 15.9 2.9 7.8 11.0 2.1 1 1 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein DUF724 PF05266.9 ETO03746.1 - 0.94 9.0 15.9 0.69 9.5 9.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.14 ETO03746.1 - 1.1 7.0 12.6 1.3 6.8 8.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family XhlA PF10779.4 ETO03746.1 - 2.7 7.9 16.7 5.5e+03 -2.7 11.6 3.1 1 1 0 1 1 1 0 Haemolysin XhlA DUF972 PF06156.8 ETO03746.1 - 5.1 7.5 20.7 27 5.1 7.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TMF_DNA_bd PF12329.3 ETO03746.1 - 6.7 6.5 22.4 0.97 9.2 5.5 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 ETO03746.1 - 7.1 6.3 26.5 1.4 8.6 7.2 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Med4 PF10018.4 ETO03746.1 - 8.7 5.6 18.8 7.9 5.8 7.5 2.8 2 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 HEAT PF02985.17 ETO03747.1 - 2e-05 24.2 2.4 0.097 12.8 0.1 4.0 4 0 0 4 4 4 2 HEAT repeat Sec6 PF06046.8 ETO03747.1 - 0.0087 14.1 0.0 0.0098 14.0 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec6 CLASP_N PF12348.3 ETO03747.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 CLASP N terminal ADH_N PF08240.7 ETO03748.1 - 1.4e-05 24.8 0.5 2.3e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF4578 PF15147.1 ETO03748.1 - 0.004 17.5 0.0 0.0041 17.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4578) C2 PF00168.25 ETO03749.1 - 1.4e-06 28.0 0.1 1.1e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 C2 domain CortBP2 PF09727.4 ETO03749.1 - 0.055 12.9 0.2 0.096 12.1 0.1 1.5 1 1 0 1 1 1 0 Cortactin-binding protein-2 Nop53 PF07767.6 ETO03749.1 - 0.13 11.2 2.9 0.14 11.1 2.0 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) FPL PF09758.4 ETO03750.1 - 5.2e-35 120.4 5.7 6e-35 120.2 4.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein RAI16-like PF10257.4 ETO03750.1 - 0.033 13.1 0.3 0.058 12.3 0.2 1.4 1 1 0 1 1 1 0 Retinoic acid induced 16-like protein Xpo1 PF08389.7 ETO03750.1 - 0.12 12.3 0.8 0.2 11.5 0.6 1.5 1 1 0 1 1 1 0 Exportin 1-like protein Protocadherin PF08374.6 ETO03750.1 - 0.3 10.6 4.0 0.4 10.2 2.8 1.2 1 0 0 1 1 1 0 Protocadherin DUF4415 PF14384.1 ETO03750.1 - 0.54 10.4 0.1 0.54 10.4 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4415) Nop16 PF09420.5 ETO03750.1 - 0.75 9.8 8.5 1 9.4 5.9 1.1 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 Hydrolase_like2 PF13246.1 ETO03751.1 - 8.9e-08 31.9 0.2 3.9e-07 29.9 0.1 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 ETO03751.1 - 3.3e-06 27.6 0.0 4.2e-06 27.3 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETO03751.1 - 0.00084 19.5 0.0 0.0011 19.2 0.0 1.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase RTP PF02334.11 ETO03752.1 - 0.00051 20.0 0.2 0.00078 19.4 0.1 1.3 1 0 0 1 1 1 1 Replication terminator protein DUF3780 PF12635.2 ETO03752.1 - 0.025 14.0 0.9 0.04 13.4 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3780) FliG_C PF01706.11 ETO03752.1 - 0.04 13.8 1.0 0.098 12.6 0.7 1.7 1 1 0 1 1 1 0 FliG C-terminal domain Xpo1 PF08389.7 ETO03752.1 - 0.056 13.3 1.1 0.078 12.8 0.8 1.3 1 0 0 1 1 1 0 Exportin 1-like protein CsgE PF10627.4 ETO03752.1 - 0.29 10.9 2.1 11 5.9 0.1 2.2 2 0 0 2 2 2 0 Curli assembly protein CsgE YpjP PF14005.1 ETO03752.1 - 0.35 10.6 4.4 1.5 8.6 0.2 2.1 1 1 1 2 2 2 0 YpjP-like protein DUF3887 PF13026.1 ETO03752.1 - 0.45 10.8 7.4 0.17 12.1 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3887) Tctex-1 PF03645.8 ETO03752.1 - 0.72 9.7 5.1 0.78 9.6 0.5 2.1 2 0 0 2 2 2 0 Tctex-1 family Spore_GerAC PF05504.6 ETO03752.1 - 0.73 9.5 12.1 0.4 10.4 0.8 2.1 1 1 1 2 2 2 0 Spore germination B3/ GerAC like, C-terminal HAND PF09110.6 ETO03752.1 - 0.87 10.0 6.6 24 5.3 4.5 2.2 1 1 0 1 1 1 0 HAND Tup_N PF08581.5 ETO03752.1 - 1.3 9.2 7.3 52 4.1 5.1 2.3 1 1 0 1 1 1 0 Tup N-terminal ARGLU PF15346.1 ETO03752.1 - 1.9 8.2 11.9 41 3.9 8.2 2.1 1 1 0 1 1 1 0 Arginine and glutamate-rich 1 HlyD_2 PF12700.2 ETO03753.1 - 0.079 12.1 5.5 0.089 11.9 3.8 1.0 1 0 0 1 1 1 0 HlyD family secretion protein CM_2 PF01817.16 ETO03753.1 - 0.19 11.8 6.6 3.7 7.7 0.9 2.3 1 1 1 2 2 2 0 Chorismate mutase type II Activator_LAG-3 PF11498.3 ETO03753.1 - 0.66 8.6 10.5 0.69 8.5 7.3 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 MRP-S26 PF14943.1 ETO03753.1 - 7.9 6.0 18.9 6.8 6.2 1.2 2.0 1 1 1 2 2 2 0 Mitochondrial ribosome subunit S26 Myb_DNA-bind_3 PF12776.2 ETO03756.1 - 0.0075 16.8 0.2 0.012 16.2 0.2 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Pex24p PF06398.6 ETO03756.1 - 0.13 11.0 0.1 0.14 10.9 0.1 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF4191 PF13829.1 ETO03756.1 - 1.5 7.8 6.4 2.3 7.2 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Tmemb_9 PF05434.6 ETO03756.1 - 8.8 6.0 9.6 16 5.2 6.7 1.4 1 1 0 1 1 1 0 TMEM9 Mito_carr PF00153.22 ETO03758.1 - 9.1e-07 28.5 0.3 1.2e-06 28.1 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial carrier protein GSH-S_N PF02951.9 ETO03758.1 - 0.13 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain Phage_int_SAM_4 PF13495.1 ETO03758.1 - 0.13 12.5 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DDE_Tnp_1 PF01609.16 ETO03760.1 - 2.7e-14 53.2 0.1 4.1e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain DEAD PF00270.24 ETO03761.1 - 2e-08 33.9 0.2 4.5e-08 32.7 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase CMS1 PF14617.1 ETO03761.1 - 6.7e-05 22.0 0.1 8.4e-05 21.7 0.1 1.3 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA PF00004.24 ETO03761.1 - 0.11 12.7 0.0 0.39 10.9 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Molybdop_Fe4S4 PF04879.11 ETO03761.1 - 0.15 11.9 0.1 0.29 10.9 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin oxidoreductase Fe4S4 domain Peptidase_C9 PF01707.11 ETO03762.1 - 0.028 14.0 0.1 0.045 13.3 0.0 1.3 1 1 0 1 1 1 0 Peptidase family C9 RepA_C PF04796.7 ETO03762.1 - 0.038 13.5 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 Plasmid encoded RepA protein Enkurin PF13864.1 ETO03762.1 - 0.25 11.5 3.9 0.46 10.7 0.2 2.3 2 0 0 2 2 2 0 Calmodulin-binding GAS2 PF02187.12 ETO03763.1 - 0.00012 21.7 0.0 0.00024 20.7 0.0 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CENP-F_leu_zip PF10473.4 ETO03763.1 - 0.00034 20.4 1.9 0.00065 19.5 1.3 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.17 ETO03763.1 - 0.0008 19.3 4.7 0.0018 18.2 3.2 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF641 PF04859.7 ETO03763.1 - 0.00088 19.0 2.1 0.0015 18.3 1.4 1.3 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) DASH_Spc34 PF08657.5 ETO03763.1 - 0.0011 18.7 0.8 0.0021 17.7 0.5 1.5 1 0 0 1 1 1 1 DASH complex subunit Spc34 ATG16 PF08614.6 ETO03763.1 - 0.0014 18.4 1.8 0.0027 17.5 1.2 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) SlyX PF04102.7 ETO03763.1 - 0.0018 18.6 10.0 0.0019 18.5 2.0 2.8 2 1 1 3 3 2 1 SlyX AAA_13 PF13166.1 ETO03763.1 - 0.0021 16.5 2.1 0.0031 16.0 1.4 1.1 1 0 0 1 1 1 1 AAA domain IncA PF04156.9 ETO03763.1 - 0.0031 17.1 2.6 0.0057 16.2 1.8 1.4 1 0 0 1 1 1 1 IncA protein ADIP PF11559.3 ETO03763.1 - 0.0031 17.4 0.7 0.0057 16.5 0.5 1.4 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding CENP-Q PF13094.1 ETO03763.1 - 0.0038 17.2 2.8 0.0074 16.3 1.9 1.4 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Spc7 PF08317.6 ETO03763.1 - 0.0053 15.4 1.6 0.0086 14.7 1.1 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Cep57_MT_bd PF06657.8 ETO03763.1 - 0.006 16.4 3.3 0.014 15.3 2.3 1.6 1 1 0 1 1 1 1 Centrosome microtubule-binding domain of Cep57 DUF869 PF05911.6 ETO03763.1 - 0.0062 14.8 3.2 0.0088 14.3 2.3 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) TBPIP PF07106.8 ETO03763.1 - 0.0069 15.9 1.0 0.015 14.8 0.7 1.5 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Atg14 PF10186.4 ETO03763.1 - 0.0069 15.3 1.6 0.0095 14.9 1.1 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 TMF_DNA_bd PF12329.3 ETO03763.1 - 0.0074 16.0 9.7 0.0074 16.0 6.7 2.2 2 1 0 2 2 1 1 TATA element modulatory factor 1 DNA binding GAS PF13851.1 ETO03763.1 - 0.0075 15.4 2.0 0.014 14.6 1.4 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding SseC PF04888.7 ETO03763.1 - 0.0084 15.4 0.6 0.015 14.6 0.4 1.4 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family Mnd1 PF03962.10 ETO03763.1 - 0.0088 15.7 0.2 0.017 14.7 0.1 1.5 1 0 0 1 1 1 1 Mnd1 family HMD PF03201.11 ETO03763.1 - 0.012 15.4 0.4 0.98 9.3 0.0 2.6 2 1 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase bZIP_1 PF00170.16 ETO03763.1 - 0.014 15.3 7.0 1 9.3 1.1 2.5 1 1 1 2 2 2 0 bZIP transcription factor TMF_TATA_bd PF12325.3 ETO03763.1 - 0.014 15.1 4.7 0.03 14.0 3.2 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF465 PF04325.8 ETO03763.1 - 0.015 14.9 7.4 0.039 13.6 5.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF465) GrpE PF01025.14 ETO03763.1 - 0.018 14.5 2.8 0.018 14.5 2.0 1.7 2 0 0 2 2 2 0 GrpE DUF2046 PF09755.4 ETO03763.1 - 0.02 13.8 3.3 0.03 13.2 2.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) Cast PF10174.4 ETO03763.1 - 0.021 12.8 2.5 0.03 12.4 1.7 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Angiomotin_C PF12240.3 ETO03763.1 - 0.022 14.2 0.9 0.06 12.8 0.6 1.8 1 0 0 1 1 1 0 Angiomotin C terminal End3 PF12761.2 ETO03763.1 - 0.023 14.3 0.6 0.023 14.3 0.4 1.5 2 0 0 2 2 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF812 PF05667.6 ETO03763.1 - 0.023 13.1 1.3 0.033 12.7 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF972 PF06156.8 ETO03763.1 - 0.025 14.9 0.5 0.047 14.0 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF4455 PF14643.1 ETO03763.1 - 0.026 13.1 1.4 0.039 12.5 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) HrpB7 PF09486.5 ETO03763.1 - 0.026 14.4 5.2 0.043 13.7 3.6 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF342 PF03961.8 ETO03763.1 - 0.03 12.7 1.5 0.042 12.2 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) NPV_P10 PF05531.7 ETO03763.1 - 0.03 14.5 0.4 0.058 13.6 0.3 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Ded_cyto PF06920.8 ETO03763.1 - 0.03 13.6 0.7 1 8.6 0.1 2.2 2 0 0 2 2 2 0 Dedicator of cytokinesis DUF2203 PF09969.4 ETO03763.1 - 0.033 14.4 0.9 0.066 13.4 0.6 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Histone_HNS PF00816.16 ETO03763.1 - 0.035 14.6 3.0 0.28 11.6 1.6 2.2 2 0 0 2 2 2 0 H-NS histone family Spc24 PF08286.6 ETO03763.1 - 0.035 13.8 1.7 0.067 12.8 1.2 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF4200 PF13863.1 ETO03763.1 - 0.036 14.0 8.6 0.11 12.4 0.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Laminin_II PF06009.7 ETO03763.1 - 0.044 13.5 1.0 0.083 12.6 0.3 1.7 2 0 0 2 2 1 0 Laminin Domain II GCOM2 PF15328.1 ETO03763.1 - 0.047 13.4 0.0 0.054 13.2 0.0 1.2 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 DUF4239 PF14023.1 ETO03763.1 - 0.055 12.8 0.1 0.085 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) VirE1 PF12189.3 ETO03763.1 - 0.059 13.5 0.1 2.3 8.3 0.0 2.4 2 0 0 2 2 2 0 Single-strand DNA-binding protein Fib_alpha PF08702.5 ETO03763.1 - 0.064 13.3 1.2 0.21 11.7 0.9 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Reo_sigmaC PF04582.7 ETO03763.1 - 0.065 12.4 0.1 0.083 12.0 0.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TMPIT PF07851.8 ETO03763.1 - 0.067 12.2 0.2 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS5 PF14817.1 ETO03763.1 - 0.067 11.7 3.6 0.093 11.2 2.5 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Ax_dynein_light PF10211.4 ETO03763.1 - 0.076 12.8 2.4 0.13 12.1 1.7 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain bZIP_2 PF07716.10 ETO03763.1 - 0.094 12.5 0.1 0.094 12.5 0.1 2.5 2 1 1 3 3 2 0 Basic region leucine zipper CALCOCO1 PF07888.6 ETO03763.1 - 0.095 10.9 1.9 0.13 10.5 1.3 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Hormone_4 PF00220.12 ETO03763.1 - 0.1 12.3 0.7 0.2 11.3 0.5 1.5 1 0 0 1 1 1 0 Neurohypophysial hormones, N-terminal Domain Med9 PF07544.8 ETO03763.1 - 0.12 12.1 6.4 1.6 8.4 4.2 2.4 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 MAP65_ASE1 PF03999.7 ETO03763.1 - 0.13 10.8 1.2 0.51 8.8 0.8 1.8 1 1 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Med4 PF10018.4 ETO03763.1 - 0.15 11.4 2.0 0.28 10.5 1.4 1.4 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 CorA PF01544.13 ETO03763.1 - 0.25 10.3 1.5 0.37 9.7 1.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Mitofilin PF09731.4 ETO03763.1 - 0.31 9.6 4.3 0.16 10.5 1.8 1.4 2 0 0 2 2 1 0 Mitochondrial inner membrane protein DivIC PF04977.10 ETO03763.1 - 0.36 10.3 12.7 0.051 13.0 1.2 2.6 2 1 1 3 3 2 0 Septum formation initiator Syntaxin PF00804.20 ETO03763.1 - 0.44 10.7 2.7 0.47 10.6 0.7 1.8 2 0 0 2 2 1 0 Syntaxin BMFP PF04380.8 ETO03763.1 - 0.46 10.6 6.8 0.14 12.3 1.0 2.4 2 0 0 2 2 2 0 Membrane fusogenic activity APG6 PF04111.7 ETO03763.1 - 0.54 9.2 5.7 0.1 11.6 1.7 1.4 2 0 0 2 2 1 0 Autophagy protein Apg6 DUF3782 PF12644.2 ETO03763.1 - 0.67 9.7 2.5 2.1 8.2 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) DUF1409 PF07197.7 ETO03763.1 - 0.77 9.8 5.9 6.3 6.9 4.1 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1409) DUF4140 PF13600.1 ETO03763.1 - 0.86 10.0 8.2 0.35 11.3 2.4 2.4 2 1 1 3 3 2 0 N-terminal domain of unknown function (DUF4140) MutS_IV PF05190.13 ETO03763.1 - 1.4 9.1 10.7 3.9 7.7 0.5 3.1 2 1 1 3 3 3 0 MutS family domain IV Phage_Mu_Gam PF07352.7 ETO03763.1 - 1.4 8.3 7.9 5.5 6.5 3.3 2.5 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein FliJ PF02050.11 ETO03763.1 - 2.1 8.3 10.7 0.22 11.5 2.7 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein Prefoldin PF02996.12 ETO03763.1 - 2.8 7.6 10.8 0.5 10.0 2.4 2.8 2 2 0 2 2 2 0 Prefoldin subunit Prefoldin_2 PF01920.15 ETO03763.1 - 3.5 7.4 9.4 0.25 11.1 2.2 2.2 2 1 0 2 2 1 0 Prefoldin subunit MerR-DNA-bind PF09278.6 ETO03763.1 - 4.1 7.8 11.9 5.8 7.3 2.3 2.5 1 1 1 2 2 2 0 MerR, DNA binding DUF1192 PF06698.6 ETO03763.1 - 7.2 6.4 13.2 0.79 9.5 1.9 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) GGDEF PF00990.16 ETO03764.1 - 5.1e-05 22.9 0.0 6.8e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 GGDEF domain Sterile PF03015.14 ETO03765.1 - 0.69 10.2 4.2 0.97 9.7 2.9 1.4 1 1 0 1 1 1 0 Male sterility protein DUF2636 PF11120.3 ETO03767.1 - 0.018 14.5 0.1 0.045 13.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2636) DUF3896 PF13035.1 ETO03768.1 - 0.077 13.0 0.5 0.077 13.0 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) DUF904 PF06005.7 ETO03768.1 - 0.11 12.8 2.1 0.19 12.0 1.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF904) UPF0449 PF15136.1 ETO03768.1 - 0.19 11.9 1.3 0.64 10.2 0.1 2.2 1 1 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF4347 PF14252.1 ETO03769.1 - 0.075 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4347) AntA PF08346.7 ETO03769.1 - 0.095 12.9 0.1 1.7 8.8 0.0 2.5 3 0 0 3 3 3 0 AntA/AntB antirepressor DUF1980 PF09323.5 ETO03771.1 - 0.59 9.8 4.1 0.79 9.4 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) U3_snoRNA_assoc PF08297.6 ETO03771.1 - 2.7 8.2 7.9 5.8 7.2 4.8 2.1 1 1 0 1 1 1 0 U3 snoRNA associated DUF4175 PF13779.1 ETO03771.1 - 9 3.8 8.8 10 3.6 6.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF3390 PF11870.3 ETO03772.1 - 0.054 13.4 0.2 0.091 12.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) DUF663 PF04950.7 ETO03773.1 - 0.21 10.5 4.4 0.43 9.5 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF663) PBP1_TM PF14812.1 ETO03773.1 - 4.6 7.6 8.8 2.6 8.4 3.4 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HR1 PF02185.11 ETO03774.1 - 0.00029 20.4 13.1 0.00083 19.0 5.0 2.1 1 1 1 2 2 2 1 Hr1 repeat Myosin_tail_1 PF01576.14 ETO03774.1 - 0.0003 18.6 10.2 0.00039 18.3 7.0 1.0 1 0 0 1 1 1 1 Myosin tail DUF3584 PF12128.3 ETO03774.1 - 0.0039 14.6 8.0 0.0045 14.3 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF3450 PF11932.3 ETO03774.1 - 0.0054 16.0 5.0 0.007 15.6 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Spc7 PF08317.6 ETO03774.1 - 0.0064 15.2 7.7 0.0083 14.8 5.4 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Fusion_gly PF00523.13 ETO03774.1 - 0.01 13.9 4.8 0.19 9.7 0.4 2.1 1 1 1 2 2 2 0 Fusion glycoprotein F0 Atg14 PF10186.4 ETO03774.1 - 0.012 14.5 8.7 0.014 14.3 6.0 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TYW3 PF02676.9 ETO03774.1 - 0.013 14.6 5.4 0.072 12.2 0.7 2.1 1 1 1 2 2 2 0 Methyltransferase TYW3 DUF869 PF05911.6 ETO03774.1 - 0.015 13.5 8.4 0.017 13.3 5.8 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) BSMAP PF12280.3 ETO03774.1 - 0.018 14.9 2.0 0.02 14.7 1.4 1.1 1 0 0 1 1 1 0 Brain specific membrane anchored protein APG6 PF04111.7 ETO03774.1 - 0.022 13.8 10.5 0.025 13.6 7.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_13 PF13166.1 ETO03774.1 - 0.026 13.0 6.7 0.031 12.7 4.6 1.0 1 0 0 1 1 1 0 AAA domain DUF4111 PF13427.1 ETO03774.1 - 0.03 14.1 1.1 0.043 13.6 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4111) OmpH PF03938.9 ETO03774.1 - 0.045 13.6 8.8 0.059 13.3 6.1 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CCP_MauG PF03150.9 ETO03774.1 - 0.054 13.8 1.3 0.062 13.5 0.9 1.1 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Reo_sigmaC PF04582.7 ETO03774.1 - 0.08 12.1 0.6 0.092 11.9 0.4 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein IFT57 PF10498.4 ETO03774.1 - 0.083 11.6 7.7 0.12 11.0 5.3 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 V_ATPase_I PF01496.14 ETO03774.1 - 0.095 10.5 3.0 0.11 10.3 2.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PilJ PF13675.1 ETO03774.1 - 0.096 13.0 4.1 0.31 11.3 2.1 1.9 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4226 PF10774.4 ETO03774.1 - 0.13 12.3 5.5 0.87 9.6 1.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4226) tRNA-synt_1f PF01921.13 ETO03774.1 - 0.13 10.9 2.2 0.15 10.6 1.5 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) Sipho_Gp157 PF05565.6 ETO03774.1 - 0.14 11.7 7.8 0.2 11.2 5.4 1.2 1 0 0 1 1 1 0 Siphovirus Gp157 DUF342 PF03961.8 ETO03774.1 - 0.15 10.4 4.2 0.17 10.2 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Syntaxin PF00804.20 ETO03774.1 - 0.15 12.1 8.0 0.84 9.8 3.6 2.1 1 1 1 2 2 2 0 Syntaxin Uds1 PF15456.1 ETO03774.1 - 0.18 11.8 9.5 0.44 10.5 6.6 1.6 1 1 0 1 1 1 0 Up-regulated During Septation Cullin_binding PF03556.10 ETO03774.1 - 0.19 11.9 1.2 0.24 11.5 0.8 1.3 1 0 0 1 1 1 0 Cullin binding DUF1178 PF06676.6 ETO03774.1 - 0.2 11.8 5.7 0.17 12.0 3.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1178) TMPIT PF07851.8 ETO03774.1 - 0.2 10.6 7.5 0.25 10.3 5.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein AAA_23 PF13476.1 ETO03774.1 - 0.22 11.8 6.3 0.25 11.6 4.4 1.1 1 0 0 1 1 1 0 AAA domain Fib_alpha PF08702.5 ETO03774.1 - 0.22 11.6 7.2 0.31 11.1 5.0 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4168 PF13767.1 ETO03774.1 - 0.35 11.5 8.5 0.17 12.5 2.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4168) Bacillus_HBL PF05791.6 ETO03774.1 - 0.37 10.1 8.2 1.4 8.2 1.0 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Snapin_Pallidin PF14712.1 ETO03774.1 - 0.44 10.8 10.5 0.26 11.5 3.7 2.2 1 1 1 2 2 2 0 Snapin/Pallidin DUF4200 PF13863.1 ETO03774.1 - 0.56 10.1 13.9 5.2 7.0 9.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Raptor_N PF14538.1 ETO03774.1 - 0.61 9.9 4.6 1.1 9.0 0.4 2.1 1 1 1 2 2 2 0 Raptor N-terminal CASPase like domain NPV_P10 PF05531.7 ETO03774.1 - 0.74 10.1 3.8 6.6 7.0 3.0 2.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.6 ETO03774.1 - 1 9.2 6.1 2.4 8.0 0.5 2.2 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Syntaxin-6_N PF09177.6 ETO03774.1 - 1.6 9.1 7.6 3.6 8.0 5.3 1.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF16 PF01519.11 ETO03774.1 - 1.6 8.9 9.2 1.4 9.1 5.2 1.6 1 1 1 2 2 2 0 Protein of unknown function DUF16 IncA PF04156.9 ETO03774.1 - 2.3 7.7 10.7 3.5 7.1 1.7 2.0 1 1 1 2 2 2 0 IncA protein zf-ZPR1 PF03367.8 ETO03774.1 - 5.4 6.1 10.1 0.085 12.0 1.5 2.0 1 1 1 2 2 2 0 ZPR1 zinc-finger domain DUF2229 PF09989.4 ETO03774.1 - 5.5 6.3 6.8 8 5.8 4.7 1.4 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Methyltransf_24 PF13578.1 ETO03776.1 - 1.6e-10 41.7 0.0 2.6e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCP_red PF08369.5 ETO03776.1 - 0.011 15.6 0.8 0.024 14.5 0.6 1.6 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit SMI1_KNR4 PF09346.5 ETO03776.1 - 0.11 12.5 0.3 0.16 11.9 0.2 1.2 1 0 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) Cast PF10174.4 ETO03777.1 - 0.004 15.2 15.8 0.0049 15.0 10.9 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Spc7 PF08317.6 ETO03777.1 - 0.019 13.6 18.4 0.023 13.3 12.7 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Fez1 PF06818.10 ETO03777.1 - 0.026 14.5 18.0 0.17 11.8 12.5 1.8 1 1 0 1 1 1 0 Fez1 ATG16 PF08614.6 ETO03777.1 - 0.06 13.1 20.3 0.14 11.9 14.1 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) TMPIT PF07851.8 ETO03777.1 - 0.07 12.1 11.1 0.078 12.0 7.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein Tropomyosin_1 PF12718.2 ETO03777.1 - 0.073 12.9 30.3 0.17 11.7 18.6 2.1 1 1 1 2 2 2 0 Tropomyosin like PilJ PF13675.1 ETO03777.1 - 0.079 13.2 10.3 0.079 13.2 4.4 2.0 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Myosin_tail_1 PF01576.14 ETO03777.1 - 0.14 9.8 25.2 0.16 9.6 17.4 1.1 1 0 0 1 1 1 0 Myosin tail Reo_sigmaC PF04582.7 ETO03777.1 - 0.15 11.2 1.7 0.17 11.0 1.2 1.0 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 ETO03777.1 - 0.29 11.2 12.7 0.34 11.0 8.8 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family IncA PF04156.9 ETO03777.1 - 0.29 10.6 26.1 0.57 9.7 18.1 1.4 1 1 0 1 1 1 0 IncA protein WEMBL PF05701.6 ETO03777.1 - 0.33 9.3 23.7 0.36 9.2 16.4 1.0 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Hanta_nucleocap PF00846.13 ETO03777.1 - 0.34 9.5 6.0 0.39 9.3 4.1 1.1 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein CENP-F_leu_zip PF10473.4 ETO03777.1 - 0.37 10.6 25.6 0.11 12.3 3.0 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Flagellin_N PF00669.15 ETO03777.1 - 0.4 10.4 7.2 0.61 9.8 4.8 1.4 1 1 0 1 1 1 0 Bacterial flagellin N-terminal helical region Spc97_Spc98 PF04130.8 ETO03777.1 - 0.44 8.8 4.2 0.53 8.5 2.9 1.0 1 0 0 1 1 1 0 Spc97 / Spc98 family AAA_13 PF13166.1 ETO03777.1 - 0.53 8.6 18.9 0.64 8.4 13.1 1.1 1 0 0 1 1 1 0 AAA domain NAP PF00956.13 ETO03777.1 - 0.6 9.1 10.4 0.77 8.8 7.2 1.2 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) DUF812 PF05667.6 ETO03777.1 - 0.63 8.4 21.9 2.2 6.6 15.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) OmpH PF03938.9 ETO03777.1 - 0.8 9.6 26.2 1.3 8.9 18.1 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4200 PF13863.1 ETO03777.1 - 0.8 9.6 26.7 0.99 9.3 18.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) APG6 PF04111.7 ETO03777.1 - 0.82 8.6 22.7 1.1 8.1 15.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3450 PF11932.3 ETO03777.1 - 1 8.5 17.5 2.6 7.2 11.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Lebercilin PF15619.1 ETO03777.1 - 1.3 8.4 23.3 0.54 9.6 11.5 1.9 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease ERM PF00769.14 ETO03777.1 - 1.3 8.4 29.8 1.8 8.0 20.6 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF3584 PF12128.3 ETO03777.1 - 1.4 6.1 22.9 1.6 5.9 15.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) EzrA PF06160.7 ETO03777.1 - 1.7 6.7 21.8 2.1 6.4 15.1 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA FemAB PF02388.11 ETO03777.1 - 1.7 7.2 20.0 1.3 7.5 4.0 2.0 1 1 1 2 2 2 0 FemAB family BLOC1_2 PF10046.4 ETO03777.1 - 1.8 8.7 16.3 55 3.9 11.3 2.2 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Z1 PF10593.4 ETO03777.1 - 1.8 7.7 7.8 2.4 7.2 5.4 1.2 1 0 0 1 1 1 0 Z1 domain DUF641 PF04859.7 ETO03777.1 - 2 8.2 16.9 3 7.6 5.2 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) V_ATPase_I PF01496.14 ETO03777.1 - 2 6.1 14.5 2.3 5.9 10.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Filament PF00038.16 ETO03777.1 - 2.1 7.7 23.7 0.78 9.1 4.9 1.9 1 1 1 2 2 2 0 Intermediate filament protein TMF_DNA_bd PF12329.3 ETO03777.1 - 2.3 8.1 28.9 12 5.8 6.3 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Cluap1 PF10234.4 ETO03777.1 - 2.5 7.2 16.7 4.5 6.4 11.6 1.4 1 1 0 1 1 1 0 Clusterin-associated protein-1 GAS PF13851.1 ETO03777.1 - 2.5 7.2 23.8 18 4.4 16.5 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Peptidase_C6 PF00851.13 ETO03777.1 - 2.7 6.5 10.5 3.1 6.3 7.3 1.0 1 0 0 1 1 1 0 Helper component proteinase DUF2353 PF09789.4 ETO03777.1 - 2.8 7.1 17.4 3.1 6.9 12.0 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) DUF1664 PF07889.7 ETO03777.1 - 2.9 7.7 8.7 5.1 6.9 5.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF342 PF03961.8 ETO03777.1 - 2.9 6.1 15.7 3.3 6.0 10.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4298 PF14131.1 ETO03777.1 - 3.3 7.6 11.0 0.77 9.6 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) Laminin_II PF06009.7 ETO03777.1 - 3.4 7.4 13.0 20 4.9 9.0 1.9 1 1 0 1 1 1 0 Laminin Domain II AATF-Che1 PF13339.1 ETO03777.1 - 3.4 7.8 13.3 4.7 7.3 9.2 1.3 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor NPV_P10 PF05531.7 ETO03777.1 - 3.4 7.9 7.4 10 6.4 0.1 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein ADIP PF11559.3 ETO03777.1 - 3.6 7.4 24.4 11 5.9 11.3 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Lectin_N PF03954.9 ETO03777.1 - 4.3 6.7 6.6 30 4.0 4.6 2.0 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain PEP-utilisers_N PF05524.8 ETO03777.1 - 5 6.9 12.4 6.1 6.6 8.6 1.1 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal LMBR1 PF04791.11 ETO03777.1 - 5.4 5.4 10.6 6 5.3 7.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2935 PF11155.3 ETO03777.1 - 5.9 6.9 12.7 32 4.6 8.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) Ax_dynein_light PF10211.4 ETO03777.1 - 6.2 6.6 24.7 1.7 8.4 11.1 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain Exonuc_VII_L PF02601.10 ETO03777.1 - 6.5 5.8 14.7 7.4 5.6 10.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF948 PF06103.6 ETO03777.1 - 6.7 6.6 7.5 7.5 6.4 1.0 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Fzo_mitofusin PF04799.8 ETO03777.1 - 7.3 5.9 14.0 1.2 8.5 2.4 2.1 1 1 1 2 2 2 0 fzo-like conserved region TMCO5 PF14992.1 ETO03777.1 - 7.6 5.5 20.9 9.2 5.3 14.5 1.1 1 0 0 1 1 1 0 TMCO5 family DUF3332 PF11810.3 ETO03777.1 - 7.6 6.1 8.9 9.8 5.7 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) DUF4446 PF14584.1 ETO03777.1 - 8.4 6.2 14.2 8.2 6.2 4.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) MbeD_MobD PF04899.7 ETO03777.1 - 9 6.2 14.1 5.2 7.0 5.1 2.2 1 1 1 2 2 2 0 MbeD/MobD like DUF4407 PF14362.1 ETO03777.1 - 9.5 5.0 15.0 13 4.6 10.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mnd1 PF03962.10 ETO03777.1 - 9.8 5.7 20.3 33 4.0 14.1 1.7 1 1 0 1 1 1 0 Mnd1 family Orbi_VP5 PF00901.12 ETO03777.1 - 10 4.2 15.9 12 3.9 11.1 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Ank_2 PF12796.2 ETO03778.1 - 2.8e-27 94.8 1.0 2.4e-14 53.4 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETO03778.1 - 2.4e-20 71.2 0.0 3.9e-07 29.5 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 ETO03778.1 - 1.1e-18 66.8 0.1 1.4e-09 37.8 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO03778.1 - 6.8e-17 59.8 0.1 0.00036 20.4 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 ETO03778.1 - 2.1e-13 50.3 0.1 0.00011 22.5 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Sec34 PF04136.10 ETO03778.1 - 0.004 16.8 0.0 0.0061 16.2 0.0 1.3 1 0 0 1 1 1 1 Sec34-like family ATP-synt_E_2 PF08112.6 ETO03779.1 - 0.21 11.6 1.7 1.6 8.8 0.2 2.4 3 0 0 3 3 3 0 ATP synthase epsilon subunit Pkinase PF00069.20 ETO03780.1 - 3e-22 79.0 0.0 3.4e-22 78.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO03780.1 - 4.6e-07 29.1 0.0 5.6e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3439 PF11921.3 ETO03781.1 - 0.0093 15.7 0.8 0.012 15.3 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Med3 PF11593.3 ETO03781.1 - 0.012 14.9 7.1 0.013 14.7 4.9 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DHHW PF14286.1 ETO03781.1 - 0.49 9.6 4.9 0.56 9.4 3.4 1.0 1 0 0 1 1 1 0 DHHW protein EVI2A PF05399.6 ETO03782.1 - 0.0045 16.2 0.3 0.0055 15.9 0.2 1.2 1 0 0 1 1 1 1 Ectropic viral integration site 2A protein (EVI2A) Menin PF05053.8 ETO03782.1 - 0.51 8.4 4.3 0.65 8.0 3.0 1.1 1 0 0 1 1 1 0 Menin DEAD PF00270.24 ETO03783.1 - 7.1e-24 84.1 0.0 7.7e-24 84.0 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase Neuropeptide_S PF14993.1 ETO03783.1 - 0.036 13.7 0.0 0.096 12.3 0.0 1.6 2 0 0 2 2 2 0 Neuropeptide S precursor protein ResIII PF04851.10 ETO03783.1 - 0.041 13.7 0.0 0.041 13.7 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF3153 PF11353.3 ETO03784.1 - 0.014 14.8 0.0 0.019 14.4 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3153) CCD PF07860.6 ETO03785.1 - 0.13 11.7 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 WisP family C-Terminal Region Homeobox PF00046.24 ETO03788.1 - 0.023 14.2 0.3 0.05 13.2 0.2 1.5 1 0 0 1 1 1 0 Homeobox domain Vac_ImportDeg PF09783.4 ETO03788.1 - 0.09 12.2 0.6 0.13 11.7 0.4 1.2 1 0 0 1 1 1 0 Vacuolar import and degradation protein Tox-MPTase5 PF15641.1 ETO03788.1 - 0.33 10.9 3.3 4.7 7.2 0.5 2.1 1 1 1 2 2 2 0 Metallopeptidase toxin 5 CobT PF06213.7 ETO03789.1 - 0.53 9.3 3.5 0.64 9.0 2.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Neur_chan_LBD PF02931.18 ETO03790.1 - 0.0074 15.4 0.3 0.01 15.0 0.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain YjgP_YjgQ PF03739.9 ETO03790.1 - 0.01 14.6 0.1 0.01 14.6 0.1 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF2463 PF09591.5 ETO03790.1 - 0.03 13.9 0.3 0.039 13.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) DUF4149 PF13664.1 ETO03790.1 - 0.043 13.8 0.4 0.061 13.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) Ribosomal_L19 PF01245.15 ETO03791.1 - 9.4e-46 154.2 2.1 2e-45 153.1 1.5 1.6 1 0 0 1 1 1 1 Ribosomal protein L19 tRNA_m1G_MT PF01746.16 ETO03791.1 - 7.5e-32 110.4 0.0 1.1e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Ribosomal_S16 PF00886.14 ETO03791.1 - 7.2e-26 89.6 0.2 1.4e-25 88.7 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S16 RimM PF01782.13 ETO03791.1 - 2.3e-18 65.9 0.1 1.6e-17 63.1 0.0 2.4 3 0 0 3 3 3 1 RimM N-terminal domain XisI PF08869.6 ETO03791.1 - 0.01 15.9 0.1 0.1 12.6 0.0 2.3 2 0 0 2 2 2 0 XisI protein Tubulin_C PF03953.12 ETO03792.1 - 1.8e-44 150.8 0.0 2.1e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Tubulin C-terminal domain AAA PF00004.24 ETO03793.1 - 4.5e-11 43.0 0.1 5e-11 42.9 0.0 1.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zot PF05707.7 ETO03793.1 - 0.0002 20.8 0.0 0.0002 20.8 0.0 1.1 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_10 PF12846.2 ETO03793.1 - 0.051 13.0 0.0 0.051 13.0 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain DUF1390 PF07150.6 ETO03795.1 - 0.18 11.1 0.9 0.24 10.7 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) Phage_tail PF04630.7 ETO03795.1 - 0.69 8.9 4.8 0.79 8.7 3.3 1.1 1 0 0 1 1 1 0 Phage major tail protein LLC1 PF14945.1 ETO03797.1 - 0.00023 21.4 1.6 0.00024 21.3 1.1 1.1 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein KLRAQ PF10205.4 ETO03797.1 - 0.0092 15.9 1.3 0.019 14.9 0.9 1.6 1 1 0 1 1 1 1 Predicted coiled-coil domain-containing protein TMF_DNA_bd PF12329.3 ETO03797.1 - 0.017 14.9 7.4 0.15 11.8 1.7 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Med9 PF07544.8 ETO03797.1 - 0.03 14.0 2.1 0.049 13.3 1.5 1.4 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Mod_r PF07200.8 ETO03797.1 - 0.032 14.1 3.8 0.036 13.9 2.7 1.0 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein RmuC PF02646.11 ETO03797.1 - 0.096 11.5 2.0 0.098 11.4 1.4 1.0 1 0 0 1 1 1 0 RmuC family GAS PF13851.1 ETO03797.1 - 0.12 11.5 4.0 0.14 11.3 2.8 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 ETO03797.1 - 0.16 11.7 3.1 0.2 11.3 2.1 1.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein SYCE1 PF15233.1 ETO03797.1 - 0.17 11.7 4.0 0.21 11.5 2.7 1.1 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 Vps5 PF09325.5 ETO03797.1 - 0.27 10.4 4.6 0.29 10.3 3.2 1.2 1 0 0 1 1 1 0 Vps5 C terminal like SPT16 PF08644.6 ETO03797.1 - 0.43 10.4 2.2 0.47 10.2 1.6 1.0 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) DUF4200 PF13863.1 ETO03797.1 - 0.51 10.3 10.8 0.18 11.7 2.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) ERF PF04404.7 ETO03798.1 - 0.13 11.8 1.3 0.25 10.8 0.7 1.7 1 1 1 2 2 2 0 ERF superfamily Protocadherin PF08374.6 ETO03798.1 - 0.14 11.7 0.3 0.15 11.7 0.2 1.1 1 0 0 1 1 1 0 Protocadherin TPR_1 PF00515.23 ETO03799.1 - 3.2e-09 36.0 0.6 5.5e-09 35.2 0.4 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO03799.1 - 7.2e-08 31.7 0.2 1.4e-07 30.8 0.2 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO03799.1 - 6e-06 25.6 0.6 1.3e-05 24.5 0.4 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO03799.1 - 1.4e-05 24.6 0.1 2.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 TPR repeat Sororin PF09666.5 ETO03799.1 - 0.0002 21.5 0.2 0.00025 21.2 0.1 1.3 1 0 0 1 1 1 1 Sororin protein TPR_12 PF13424.1 ETO03799.1 - 0.00097 19.0 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat Ribosomal_60s PF00428.14 ETO03799.1 - 0.0063 16.8 1.8 0.011 16.1 1.3 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein TPR_6 PF13174.1 ETO03799.1 - 0.0065 16.8 0.2 0.013 15.8 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO03799.1 - 0.0083 16.4 0.2 0.014 15.7 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat Bcl-2_BAD PF10514.4 ETO03799.1 - 0.012 15.5 4.3 0.016 15.1 3.0 1.2 1 0 0 1 1 1 0 Pro-apoptotic Bcl-2 protein, BAD TPR_17 PF13431.1 ETO03799.1 - 0.014 15.5 5.5 0.21 11.8 0.0 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat OSTMP1 PF09777.4 ETO03799.1 - 0.026 13.6 0.2 0.047 12.8 0.1 1.4 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor TPR_14 PF13428.1 ETO03799.1 - 0.039 14.5 0.0 0.074 13.7 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3085 PF11284.3 ETO03799.1 - 0.068 13.3 0.1 0.098 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3085) ChAPs PF09295.5 ETO03799.1 - 0.094 11.4 0.1 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_7 PF13176.1 ETO03799.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat MCLC PF05934.6 ETO03799.1 - 0.13 10.4 0.4 0.16 10.2 0.3 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) NARP1 PF12569.3 ETO03799.1 - 0.14 10.8 0.0 0.14 10.8 0.0 2.0 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 DUF4611 PF15387.1 ETO03799.1 - 6.1 7.0 9.6 7.5 6.7 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) AA_permease PF00324.16 ETO03801.1 - 6.1e-07 28.1 0.1 8.5e-07 27.6 0.1 1.2 1 0 0 1 1 1 1 Amino acid permease SecG PF03840.9 ETO03801.1 - 0.04 13.6 0.1 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 Preprotein translocase SecG subunit DUF1637 PF07847.7 ETO03801.1 - 0.085 12.2 0.0 0.095 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1637) MRAP PF15183.1 ETO03801.1 - 0.17 11.5 0.7 25 4.5 0.0 2.9 3 0 0 3 3 3 0 Melanocortin-2 receptor accessory protein family Cor1 PF04803.7 ETO03802.1 - 0.0039 16.9 3.8 0.0046 16.7 2.6 1.1 1 0 0 1 1 1 1 Cor1/Xlr/Xmr conserved region BLVR PF06375.6 ETO03802.1 - 0.0055 16.5 9.4 0.0068 16.2 6.5 1.1 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) DUF2240 PF09999.4 ETO03802.1 - 0.023 14.1 0.3 0.03 13.7 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2240) UPF0184 PF03670.8 ETO03802.1 - 0.029 14.5 0.2 0.038 14.1 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Hemagglutinin PF00509.13 ETO03802.1 - 0.052 11.6 1.7 0.057 11.5 1.1 1.0 1 0 0 1 1 1 0 Haemagglutinin DUF1351 PF07083.6 ETO03802.1 - 0.068 12.7 7.8 0.071 12.7 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) AATF-Che1 PF13339.1 ETO03802.1 - 0.084 13.0 4.1 0.11 12.6 2.8 1.3 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor GldM_N PF12081.3 ETO03802.1 - 0.12 11.9 3.6 0.11 11.9 2.5 1.1 1 0 0 1 1 1 0 GldM N-terminal domain Phi-29_GP16_7 PF06720.6 ETO03802.1 - 0.12 11.9 1.8 0.15 11.7 1.2 1.2 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 CorA PF01544.13 ETO03802.1 - 0.19 10.7 0.6 0.21 10.5 0.4 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein RasGAP PF00616.14 ETO03802.1 - 0.3 10.7 4.9 0.34 10.5 3.4 1.0 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase OMS28_porin PF03532.8 ETO03802.1 - 0.37 9.8 3.8 0.39 9.7 2.6 1.1 1 0 0 1 1 1 0 OMS28 porin AAA_32 PF13654.1 ETO03802.1 - 0.64 8.6 3.0 0.65 8.5 2.1 1.0 1 0 0 1 1 1 0 AAA domain Med8 PF10232.4 ETO03802.1 - 0.68 9.4 3.0 0.81 9.1 2.0 1.1 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 DUF4163 PF13739.1 ETO03802.1 - 1.1 10.1 4.0 1.1 10.0 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4163) RE_TdeIII PF09520.5 ETO03802.1 - 1.6 7.9 4.7 1.7 7.9 3.3 1.1 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII DUF1754 PF08555.5 ETO03802.1 - 4.4 7.9 14.2 5.7 7.5 9.8 1.2 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Macoilin PF09726.4 ETO03802.1 - 6.5 4.9 8.1 6.3 4.9 5.6 1.0 1 0 0 1 1 1 0 Transmembrane protein 2OG-FeII_Oxy_5 PF13759.1 ETO03804.1 - 1.4e-06 28.4 0.0 2.4e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Cupin_2 PF07883.6 ETO03804.1 - 0.014 14.8 0.0 0.027 13.9 0.0 1.6 1 1 0 1 1 1 0 Cupin domain 2OG-FeII_Oxy_3 PF13640.1 ETO03804.1 - 0.017 15.5 0.0 0.023 15.2 0.0 1.2 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Mem_trans PF03547.13 ETO03805.1 - 0.15 10.2 1.1 0.18 10.0 0.8 1.3 1 1 0 1 1 1 0 Membrane transport protein G-alpha PF00503.15 ETO03806.1 - 2.3e-15 56.1 0.0 2.3e-15 56.1 0.0 2.0 2 0 0 2 2 2 1 G-protein alpha subunit FancD2 PF14631.1 ETO03806.1 - 0.0031 14.6 0.5 0.0036 14.4 0.4 1.1 1 0 0 1 1 1 1 Fanconi anaemia protein FancD2 nuclease SelP_N PF04592.9 ETO03806.1 - 0.018 14.3 4.4 0.025 13.9 3.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 ETO03806.1 - 0.078 11.9 0.1 0.13 11.2 0.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Trypan_PARP PF05887.6 ETO03806.1 - 0.11 12.3 2.7 0.16 11.7 1.9 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) BTV_NS2 PF04514.7 ETO03806.1 - 0.13 11.1 5.4 0.19 10.6 3.8 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF1510 PF07423.6 ETO03806.1 - 1.2 8.4 15.3 2.1 7.6 10.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2201_N PF13203.1 ETO03806.1 - 2.5 7.1 7.2 3.6 6.6 5.0 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Pox_Ag35 PF03286.9 ETO03806.1 - 4.2 6.8 11.9 7.6 6.0 8.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Kelch_1 PF01344.20 ETO03809.1 - 0.018 14.5 2.5 0.86 9.2 0.2 2.4 2 1 0 2 2 2 0 Kelch motif Kelch_4 PF13418.1 ETO03809.1 - 0.052 13.3 0.3 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO03809.1 - 0.084 13.0 0.7 14 6.0 0.2 2.5 2 1 0 2 2 2 0 Kelch motif DUF4183 PF13799.1 ETO03809.1 - 0.14 11.9 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4183) DUF4362 PF14275.1 ETO03810.1 - 0.0037 17.2 0.9 0.0037 17.2 0.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4362) Mcp5_PH PF12814.2 ETO03811.1 - 9.9e-05 22.2 0.0 0.00012 22.0 0.0 1.1 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology SLX9 PF15341.1 ETO03812.1 - 0.017 15.5 2.5 0.06 13.7 0.1 2.0 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 Annexin PF00191.15 ETO03813.1 - 2.3e-13 49.7 0.9 3.7e-08 33.1 0.0 3.1 3 0 0 3 3 3 2 Annexin Lycopene_cycl PF05834.7 ETO03814.1 - 0.054 12.4 0.2 0.068 12.0 0.1 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein zf-SAP30 PF13866.1 ETO03814.1 - 0.67 9.6 3.7 0.59 9.8 1.0 2.0 2 0 0 2 2 2 0 SAP30 zinc-finger BSP_II PF05432.6 ETO03815.1 - 0.51 9.5 7.7 0.86 8.8 5.3 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF572 PF04502.8 ETO03815.1 - 8.1 5.5 27.0 9.5 5.3 18.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) MMPL PF03176.10 ETO03816.1 - 1.5e-22 79.7 1.2 2.1e-22 79.2 0.8 1.1 1 0 0 1 1 1 1 MMPL family ACR_tran PF00873.14 ETO03816.1 - 0.11 9.8 1.9 0.12 9.7 1.3 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family DUF4229 PF14012.1 ETO03816.1 - 0.26 11.2 2.8 0.5 10.2 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4229) DUF778 PF05608.7 ETO03818.1 - 0.0083 16.0 0.8 0.0093 15.9 0.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF778) DUF2465 PF10239.4 ETO03818.1 - 0.016 14.4 0.1 0.017 14.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2465) DcuA_DcuB PF03605.9 ETO03818.1 - 0.17 10.6 0.4 0.19 10.4 0.3 1.0 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter ADPrib_exo_Tox PF03496.9 ETO03818.1 - 0.19 10.9 2.6 0.21 10.7 1.8 1.1 1 0 0 1 1 1 0 ADP-ribosyltransferase exoenzyme TPR_12 PF13424.1 ETO03819.1 - 1.7e-44 149.6 4.7 3.2e-25 87.8 0.3 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO03819.1 - 6.9e-32 108.4 0.0 2.7e-09 36.6 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO03819.1 - 5.7e-25 85.1 2.9 6.1e-10 38.1 0.1 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO03819.1 - 7.3e-25 85.5 19.2 3.5e-11 42.2 1.1 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO03819.1 - 7.5e-25 86.3 8.0 1.5e-18 66.1 0.7 3.0 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 ETO03819.1 - 3.2e-21 73.4 13.0 8.2e-09 34.7 0.3 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO03819.1 - 2.3e-18 64.5 23.0 1.4e-08 33.8 2.2 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO03819.1 - 9.6e-14 50.3 3.4 0.00042 20.3 0.0 4.1 4 1 0 4 4 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO03819.1 - 2e-09 37.8 0.0 2.6e-05 24.7 0.0 3.1 1 1 1 2 2 2 1 Tetratricopeptide repeat PPR PF01535.15 ETO03819.1 - 2.5e-07 30.1 1.6 0.015 15.2 0.0 3.4 3 0 0 3 3 3 2 PPR repeat TPR_14 PF13428.1 ETO03819.1 - 1.8e-06 28.0 0.0 0.022 15.3 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_3 PF07720.7 ETO03819.1 - 1.1e-05 25.0 11.6 0.0058 16.4 0.2 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO03819.1 - 2.6e-05 24.2 9.9 0.0073 16.4 2.2 2.7 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETO03819.1 - 8.6e-05 22.7 3.5 0.04 14.3 0.0 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO03819.1 - 0.00027 20.0 0.5 0.064 12.5 0.0 3.2 3 0 0 3 3 3 1 SHNi-TPR SNAP PF14938.1 ETO03819.1 - 0.00047 19.3 3.5 0.0012 18.0 2.0 1.8 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP 14-3-3 PF00244.15 ETO03819.1 - 0.0014 17.8 1.1 0.018 14.0 0.4 2.1 1 1 1 2 2 2 1 14-3-3 protein TPR_19 PF14559.1 ETO03819.1 - 0.003 17.8 0.6 0.4 11.0 0.1 2.6 1 1 2 3 3 3 2 Tetratricopeptide repeat DUF2225 PF09986.4 ETO03819.1 - 0.0049 16.3 4.1 0.22 10.9 0.2 2.2 1 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) RPN7 PF10602.4 ETO03819.1 - 0.0056 16.0 5.4 0.28 10.5 0.2 2.9 1 1 1 2 2 2 1 26S proteasome subunit RPN7 MIT PF04212.13 ETO03819.1 - 0.008 16.0 9.7 0.16 11.8 0.9 3.5 3 1 1 4 4 4 1 MIT (microtubule interacting and transport) domain FATC PF02260.15 ETO03819.1 - 0.0088 15.4 1.6 0.38 10.2 0.0 2.6 3 0 0 3 3 3 1 FATC domain Sel1 PF08238.7 ETO03819.1 - 0.01 16.4 8.9 0.22 12.1 0.1 4.3 4 0 0 4 4 4 0 Sel1 repeat DUF386 PF04074.7 ETO03819.1 - 0.013 14.9 5.0 0.017 14.6 2.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF386) Pep3_Vps18 PF05131.9 ETO03819.1 - 0.019 14.3 0.3 7.4 5.9 0.0 2.7 3 0 0 3 3 3 0 Pep3/Vps18/deep orange family DUF3568 PF12092.3 ETO03819.1 - 0.023 14.4 0.4 19 4.9 0.0 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF3568) Vps39_1 PF10366.4 ETO03819.1 - 0.024 14.6 2.8 10 6.1 0.1 3.2 1 1 2 3 3 3 0 Vacuolar sorting protein 39 domain 1 Enkurin PF13864.1 ETO03819.1 - 0.037 14.2 0.3 0.51 10.5 0.1 2.4 1 1 2 3 3 3 0 Calmodulin-binding Sipho_tail PF05709.6 ETO03819.1 - 0.074 12.1 0.8 2.2 7.3 0.1 2.0 1 1 1 2 2 2 0 Phage tail protein Syntaxin_2 PF14523.1 ETO03819.1 - 0.081 12.9 0.1 3 7.9 0.0 2.3 1 1 1 2 2 2 0 Syntaxin-like protein TPR_9 PF13371.1 ETO03819.1 - 0.087 12.6 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF627 PF04781.7 ETO03819.1 - 0.096 12.3 5.6 2.5 7.7 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF627) PPR_2 PF13041.1 ETO03819.1 - 0.14 12.1 2.6 3.9 7.5 0.0 2.8 3 0 0 3 3 3 0 PPR repeat family bPH_3 PF14470.1 ETO03819.1 - 0.2 11.9 3.8 4.7 7.5 0.3 2.8 1 1 2 3 3 3 0 Bacterial PH domain ATP-synt_E_2 PF08112.6 ETO03819.1 - 0.42 10.6 10.1 3.4 7.8 0.2 3.8 4 0 0 4 4 4 0 ATP synthase epsilon subunit Ubiq-assoc PF09145.5 ETO03819.1 - 0.52 10.2 7.1 11 5.9 0.1 4.5 3 1 2 5 5 5 0 Ubiquitin-associated NYN PF01936.13 ETO03820.1 - 9.2e-08 32.4 0.1 1.2e-07 32.1 0.1 1.2 1 0 0 1 1 1 1 NYN domain Radical_SAM PF04055.16 ETO03821.1 - 5.8e-14 52.6 0.0 1e-12 48.5 0.0 2.1 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 ETO03821.1 - 1.7e-06 28.0 0.0 3.5e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 ETO03821.1 - 0.011 15.9 0.1 0.021 14.9 0.1 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain Cation_efflux PF01545.16 ETO03822.1 - 1e-57 195.3 14.3 1.3e-57 195.1 9.9 1.0 1 0 0 1 1 1 1 Cation efflux family Dynactin_p22 PF07426.6 ETO03822.1 - 0.0002 20.7 0.8 0.0025 17.1 0.1 2.1 2 0 0 2 2 2 1 Dynactin subunit p22 CTP_transf_3 PF02348.14 ETO03823.1 - 1.3e-31 109.9 0.0 1.7e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.2 ETO03823.1 - 1.6e-07 31.5 0.0 1.9e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain CofC PF01983.11 ETO03823.1 - 0.02 13.8 1.3 0.089 11.7 0.3 2.0 2 0 0 2 2 2 0 Guanylyl transferase CofC like Phytase-like PF13449.1 ETO03824.1 - 4.1e-30 105.1 0.2 5.6e-30 104.7 0.1 1.1 1 0 0 1 1 1 1 Esterase-like activity of phytase SdiA-regulated PF06977.6 ETO03824.1 - 0.02 13.8 0.0 0.042 12.7 0.0 1.6 1 0 0 1 1 1 0 SdiA-regulated NHL PF01436.16 ETO03824.1 - 0.059 13.3 0.0 0.51 10.4 0.0 2.5 2 0 0 2 2 2 0 NHL repeat SSP160 PF06933.6 ETO03825.1 - 0.0092 14.0 8.3 0.012 13.6 5.8 1.3 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 HAUS-augmin3 PF14932.1 ETO03825.1 - 0.028 13.6 1.1 0.04 13.1 0.8 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF4187 PF13821.1 ETO03825.1 - 0.21 11.2 3.0 0.46 10.1 2.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4187) Mucin PF01456.12 ETO03825.1 - 1.9 8.2 24.8 0.13 12.0 11.8 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF258 PF03193.11 ETO03827.1 - 6.3e-06 25.4 0.4 6.9e-05 22.0 0.3 2.3 1 1 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 ETO03827.1 - 4e-05 23.5 0.0 7.8e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 ETO03827.1 - 0.001 19.3 0.0 0.0019 18.4 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 ETO03827.1 - 0.0037 16.7 0.0 0.0062 16.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain Dynamin_N PF00350.18 ETO03827.1 - 0.0077 16.0 1.3 0.52 10.1 0.0 2.4 1 1 1 2 2 2 1 Dynamin family AAA_25 PF13481.1 ETO03827.1 - 0.018 14.4 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 ETO03827.1 - 0.025 14.7 0.1 0.65 10.1 0.0 2.5 2 1 1 3 3 3 0 AAA domain Septin PF00735.13 ETO03827.1 - 0.027 13.4 0.2 0.049 12.6 0.0 1.5 2 0 0 2 2 2 0 Septin AAA_16 PF13191.1 ETO03827.1 - 0.032 14.2 0.0 0.061 13.3 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 ETO03827.1 - 0.088 12.7 0.6 0.14 12.1 0.4 1.5 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 ETO03827.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.1 ETO03827.1 - 0.14 12.5 0.2 0.24 11.7 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 ETO03827.1 - 0.14 12.4 1.6 0.16 12.2 1.1 1.6 1 1 0 1 1 1 0 AAA domain Peptidase_S49_N PF08496.5 ETO03828.1 - 0.97 9.2 6.0 1.4 8.7 4.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NST1 PF13945.1 ETO03828.1 - 3.6 7.6 9.3 4.7 7.2 6.5 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Peptidase_M24 PF00557.19 ETO03829.1 - 4.3e-26 91.7 0.0 5.5e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Spore_coat_CotO PF14153.1 ETO03830.1 - 2.4 7.5 15.9 2.6 7.4 11.0 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF3367 PF11847.3 ETO03830.1 - 4.3 5.1 8.0 4.8 4.9 5.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) SR-25 PF10500.4 ETO03830.1 - 8.6 5.7 36.2 1.7 8.0 21.7 1.8 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Mucin PF01456.12 ETO03831.1 - 4.5 7.0 14.5 6.7 6.4 10.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Rtf2 PF04641.7 ETO03832.1 - 0.0068 15.6 8.4 0.0078 15.4 5.8 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger SID-1_RNA_chan PF13965.1 ETO03832.1 - 0.2 9.7 3.1 0.23 9.5 2.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RNA_pol_Rpb1_5 PF04998.12 ETO03832.1 - 0.28 10.4 2.8 0.32 10.2 1.9 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 WW PF00397.21 ETO03833.1 - 0.13 12.1 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 WW domain Ank_5 PF13857.1 ETO03834.1 - 0.0013 18.9 0.1 0.0031 17.7 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF2899 PF11449.3 ETO03834.1 - 0.007 15.5 0.2 0.015 14.4 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2899) Ank_2 PF12796.2 ETO03834.1 - 0.0095 16.2 0.0 0.057 13.7 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO03834.1 - 0.038 14.5 0.0 0.096 13.2 0.0 1.7 1 1 0 1 1 1 0 Ankyrin repeats (many copies) DUF1640 PF07798.6 ETO03835.1 - 6.6e-05 23.0 1.9 0.0001 22.4 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) BcsB PF03170.8 ETO03835.1 - 0.0011 17.0 0.4 0.0014 16.7 0.3 1.1 1 0 0 1 1 1 1 Bacterial cellulose synthase subunit ARA70 PF12489.3 ETO03835.1 - 0.016 15.2 2.9 0.025 14.5 2.0 1.3 1 0 0 1 1 1 0 Nuclear coactivator BTV_NS2 PF04514.7 ETO03835.1 - 0.025 13.4 2.7 0.031 13.1 1.8 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Mgr1 PF08602.5 ETO03835.1 - 0.064 12.2 2.8 0.086 11.8 2.0 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit TMF_TATA_bd PF12325.3 ETO03835.1 - 0.092 12.4 7.1 0.38 10.5 4.8 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIVA PF05103.8 ETO03835.1 - 0.1 12.6 4.5 0.15 12.0 3.1 1.4 1 0 0 1 1 1 0 DivIVA protein IncA PF04156.9 ETO03835.1 - 0.14 11.7 2.9 1.1 8.8 1.4 2.1 2 0 0 2 2 2 0 IncA protein ABC_tran_2 PF12848.2 ETO03835.1 - 0.19 11.5 5.9 0.31 10.9 4.1 1.2 1 0 0 1 1 1 0 ABC transporter DUF972 PF06156.8 ETO03835.1 - 0.39 11.0 3.9 0.6 10.4 2.3 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF972) DUF2205 PF10224.4 ETO03835.1 - 0.45 10.1 4.4 0.38 10.3 1.6 1.9 1 1 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) GET2 PF08690.5 ETO03835.1 - 0.53 9.4 3.9 0.68 9.1 2.7 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 HALZ PF02183.13 ETO03835.1 - 0.67 9.7 6.7 0.68 9.6 1.2 2.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF4407 PF14362.1 ETO03835.1 - 4.3 6.2 7.3 6.5 5.6 5.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) RBD-FIP PF09457.5 ETO03835.1 - 5.9 6.7 8.0 1 9.2 2.7 1.8 2 0 0 2 2 2 0 FIP domain TAF1D PF15333.1 ETO03836.1 - 0.59 9.8 16.0 0.093 12.5 8.4 1.5 1 1 0 1 1 1 0 TATA box-binding protein-associated factor 1D SAM_1 PF00536.25 ETO03837.1 - 1.9e-21 75.9 0.0 2.5e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO03837.1 - 4.6e-19 68.0 0.1 6.2e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 ETO03837.1 - 4.4e-05 23.1 0.2 6.6e-05 22.5 0.2 1.3 1 1 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Ste50p-SAM PF09235.5 ETO03837.1 - 0.082 12.9 0.1 0.18 11.8 0.1 1.6 1 1 0 1 1 1 0 Ste50p, sterile alpha motif BLVR PF06375.6 ETO03837.1 - 5.4 6.8 9.8 8.9 6.1 6.8 1.4 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) HJURP_C PF12347.3 ETO03838.1 - 0.035 13.6 0.2 0.035 13.6 0.2 2.3 2 1 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat CASP_C PF08172.7 ETO03839.1 - 0.0014 17.7 8.7 0.12 11.3 0.6 2.3 2 0 0 2 2 2 2 CASP C terminal DUF972 PF06156.8 ETO03839.1 - 0.081 13.2 2.6 0.11 12.8 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Cache_2 PF08269.6 ETO03839.1 - 0.12 12.3 0.3 0.17 11.8 0.2 1.2 1 0 0 1 1 1 0 Cache domain Cep57_CLD PF14073.1 ETO03839.1 - 0.17 11.6 4.1 0.23 11.2 2.8 1.1 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 Golgin_A5 PF09787.4 ETO03839.1 - 0.24 9.8 11.2 1 7.8 1.9 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 Cep57_CLD_2 PF14197.1 ETO03839.1 - 0.72 9.8 6.6 1.2 9.1 4.6 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 GP41 PF00517.12 ETO03839.1 - 1.6 8.2 8.8 4.4 6.8 0.8 2.1 2 0 0 2 2 2 0 Retroviral envelope protein DUF3399 PF11879.3 ETO03839.1 - 2.1 8.5 7.8 1.2 9.4 3.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3399) FlxA PF14282.1 ETO03839.1 - 8.8 6.3 9.7 4.7 7.1 1.8 2.5 1 1 1 2 2 2 0 FlxA-like protein Cullin PF00888.17 ETO03840.1 - 1.8e-21 76.3 0.7 2e-21 76.2 0.5 1.0 1 0 0 1 1 1 1 Cullin family DUF2132 PF09905.4 ETO03840.1 - 0.017 15.0 0.3 0.037 13.9 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2132) DUF2385 PF09539.5 ETO03840.1 - 0.084 13.2 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2385) HALZ PF02183.13 ETO03842.1 - 0.032 13.9 0.5 0.068 12.8 0.3 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper PASTA PF03793.14 ETO03842.1 - 0.11 12.1 0.7 0.47 10.1 0.1 2.4 2 1 1 3 3 3 0 PASTA domain Spectrin PF00435.16 ETO03842.1 - 0.82 9.9 8.2 2.5 8.4 1.0 2.3 2 0 0 2 2 2 0 Spectrin repeat DUF1387 PF07139.6 ETO03842.1 - 0.93 9.0 11.7 1.1 8.8 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) FlaG PF03646.10 ETO03842.1 - 4.5 7.4 16.0 0.48 10.5 4.1 3.2 3 1 0 3 3 3 0 FlaG protein GAS PF13851.1 ETO03843.1 - 0.0087 15.2 23.8 0.21 10.7 10.7 2.4 2 1 0 2 2 2 2 Growth-arrest specific micro-tubule binding Laminin_II PF06009.7 ETO03843.1 - 0.024 14.4 12.0 0.06 13.0 4.3 2.3 1 1 1 2 2 2 0 Laminin Domain II NYD-SP28 PF14772.1 ETO03843.1 - 0.024 14.7 2.2 0.024 14.7 1.5 3.1 2 1 1 3 3 3 0 Sperm tail DNA_pol3_beta_3 PF02768.10 ETO03843.1 - 0.03 13.8 4.3 0.34 10.4 0.9 2.4 2 0 0 2 2 2 0 DNA polymerase III beta subunit, C-terminal domain DUF1947 PF09183.5 ETO03843.1 - 0.059 13.1 0.1 0.059 13.1 0.1 3.4 4 0 0 4 4 3 0 Domain of unknown function (DUF1947) IL2 PF00715.12 ETO03843.1 - 0.077 12.7 8.5 0.019 14.6 2.3 2.0 1 1 1 2 2 2 0 Interleukin 2 Tweety PF04906.8 ETO03843.1 - 0.1 10.9 2.3 0.11 10.8 1.3 1.3 1 1 0 1 1 1 0 Tweety DUF916 PF06030.7 ETO03843.1 - 0.11 12.3 1.1 0.17 11.6 0.4 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF916) SlyX PF04102.7 ETO03843.1 - 0.2 12.0 14.9 0.59 10.5 0.3 3.6 2 1 1 3 3 3 0 SlyX Apolipoprotein PF01442.13 ETO03843.1 - 0.21 11.0 13.8 0.51 9.8 9.6 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain CDC37_C PF08564.5 ETO03843.1 - 0.23 11.3 12.3 0.14 12.0 4.3 2.7 1 1 2 3 3 3 0 Cdc37 C terminal domain HlyE PF06109.8 ETO03843.1 - 0.26 10.2 5.2 0.048 12.6 1.2 1.5 2 0 0 2 2 2 0 Haemolysin E (HlyE) DUF3799 PF12684.2 ETO03843.1 - 0.29 10.4 8.8 0.092 12.0 4.1 1.5 2 0 0 2 2 2 0 PDDEXK-like domain of unknown function (DUF3799) PEP-utilisers_N PF05524.8 ETO03843.1 - 0.44 10.3 6.8 0.32 10.7 0.2 2.5 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Baculo_PEP_C PF04513.7 ETO03843.1 - 0.59 9.9 5.1 0.52 10.1 1.6 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.7 ETO03843.1 - 0.88 9.3 17.0 1.1 8.9 3.2 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.2 ETO03843.1 - 1.3 8.8 24.8 0.95 9.3 4.2 2.6 2 1 0 2 2 2 0 Tropomyosin like CDC37_N PF03234.9 ETO03843.1 - 1.6 9.0 13.2 4.4 7.5 9.2 1.8 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DUF211 PF02680.9 ETO03843.1 - 1.8 8.4 5.9 5.2 6.9 0.6 2.4 1 1 0 2 2 2 0 Uncharacterized ArCR, COG1888 Prominin PF05478.6 ETO03843.1 - 1.8 6.0 10.7 2.1 5.7 7.4 1.0 1 0 0 1 1 1 0 Prominin Cytochrom_B562 PF07361.6 ETO03843.1 - 1.8 8.9 8.7 4.8 7.6 4.4 2.2 1 1 1 2 2 2 0 Cytochrome b562 Med30 PF11315.3 ETO03843.1 - 2.7 8.1 15.6 0.14 12.3 0.9 2.2 1 1 1 2 2 2 0 Mediator complex subunit 30 Bap31 PF05529.7 ETO03843.1 - 6 6.2 15.0 2.3 7.6 2.1 2.4 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like Ion_trans PF00520.26 ETO03844.1 - 7.6e-20 71.0 9.8 1.1e-19 70.5 6.8 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.11 ETO03844.1 - 1.6e-11 43.7 2.4 1.6e-11 43.7 1.6 2.2 1 1 1 2 2 2 1 Ion channel CHAT PF12770.2 ETO03845.1 - 2.7e-11 43.1 0.2 3.2e-11 42.8 0.1 1.1 1 0 0 1 1 1 1 CHAT domain Peptidase_C25 PF01364.13 ETO03845.1 - 0.031 13.2 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C25 ParBc_2 PF08857.6 ETO03846.1 - 2.1e-25 89.4 2.0 5.6e-21 75.0 0.2 2.1 2 0 0 2 2 2 2 Putative ParB-like nuclease Ferrochelatase PF00762.14 ETO03847.1 - 8.3e-45 153.1 0.0 9.2e-45 152.9 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase DUF4534 PF15049.1 ETO03848.1 - 0.045 13.3 0.1 0.093 12.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4534) Ferric_reduct PF01794.14 ETO03850.1 - 0.00026 21.0 11.0 0.0018 18.3 1.4 2.6 1 1 1 2 2 2 2 Ferric reductase like transmembrane component PerB PF06590.6 ETO03850.1 - 0.068 13.4 0.3 0.096 12.9 0.2 1.3 1 0 0 1 1 1 0 PerB protein Cation_ATPase_C PF00689.16 ETO03850.1 - 0.11 12.0 8.3 0.24 10.8 2.4 2.2 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus SNARE_assoc PF09335.6 ETO03850.1 - 0.16 12.1 5.3 0.34 11.1 0.4 2.1 1 1 1 2 2 2 0 SNARE associated Golgi protein TMEM237 PF15383.1 ETO03850.1 - 0.17 10.9 4.7 0.24 10.4 3.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 237 Pho86 PF11124.3 ETO03850.1 - 1.5 7.7 4.9 3.5 6.5 0.1 2.0 1 1 0 2 2 2 0 Inorganic phosphate transporter Pho86 MUG2_C PF08593.5 ETO03851.1 - 0.16 12.2 0.5 0.5 10.6 0.0 2.0 2 0 0 2 2 2 0 Meiotically up-regulated glycoproteins C-terminal RNase_PH PF01138.16 ETO03852.1 - 0.00012 22.4 0.1 0.00026 21.2 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Amino_oxidase PF01593.19 ETO03854.1 - 0.11 11.5 0.1 0.17 10.9 0.1 1.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 ETO03854.1 - 0.15 12.4 0.2 0.22 11.9 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CEP19 PF14933.1 ETO03856.1 - 3.1 8.0 11.0 2 8.6 6.0 2.0 1 1 0 1 1 1 0 CEP19-like protein BCS1_N PF08740.6 ETO03857.1 - 0.87 9.1 9.9 0.19 11.2 4.3 1.8 1 1 1 2 2 2 0 BCS1 N terminal RhoGEF PF00621.15 ETO03860.1 - 4.4e-07 29.9 0.1 7.3e-07 29.2 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain Flavodoxin_1 PF00258.20 ETO03861.1 - 8.9e-22 77.6 0.1 1.2e-21 77.2 0.1 1.2 1 0 0 1 1 1 1 Flavodoxin Pkinase PF00069.20 ETO03863.1 - 6.7e-21 74.6 0.0 7.7e-21 74.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO03863.1 - 2.4e-10 39.9 0.0 2.8e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO03863.1 - 0.025 13.6 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO03863.1 - 0.042 13.5 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Med25 PF11232.3 ETO03865.1 - 0.018 14.7 0.9 0.027 14.1 0.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 25 PTOV activation and synapsin 2 Pkinase PF00069.20 ETO03866.1 - 2.9e-35 121.6 0.0 3.1e-35 121.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO03866.1 - 5.6e-19 68.2 0.0 6.1e-19 68.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO03866.1 - 0.023 13.6 0.0 0.026 13.5 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 ETO03866.1 - 0.029 13.4 0.0 0.034 13.1 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Adaptin_N PF01602.15 ETO03868.1 - 1.6e-38 132.3 0.0 1.9e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 ETO03868.1 - 2.5e-09 37.2 0.1 4.1e-09 36.5 0.0 1.3 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 ETO03868.1 - 2.5e-08 34.0 0.0 4.7e-05 23.5 0.0 2.1 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 ETO03868.1 - 2.5e-06 27.0 2.4 0.13 12.3 0.0 4.4 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 ETO03868.1 - 0.012 16.0 0.4 2.2 8.8 0.0 3.2 2 1 2 4 4 4 0 HEAT-like repeat NOC3p PF07540.6 ETO03868.1 - 0.019 15.2 0.1 5.3 7.3 0.0 2.2 2 0 0 2 2 2 0 Nucleolar complex-associated protein RasGEF_N_2 PF14663.1 ETO03868.1 - 0.097 12.6 0.2 0.27 11.1 0.0 1.9 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Arm PF00514.18 ETO03868.1 - 0.86 9.5 0.0 0.86 9.5 0.0 3.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Macoilin PF09726.4 ETO03869.1 - 4 5.5 15.2 5.1 5.2 10.5 1.1 1 0 0 1 1 1 0 Transmembrane protein RRM_1 PF00076.17 ETO03870.1 - 8.1e-05 22.1 0.7 0.00012 21.6 0.0 1.8 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO03870.1 - 0.0013 18.6 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ima1_N PF09779.4 ETO03870.1 - 0.03 14.8 0.3 0.042 14.3 0.0 1.4 2 0 0 2 2 2 0 Ima1 N-terminal domain RRM_5 PF13893.1 ETO03870.1 - 0.03 14.1 0.1 0.073 12.9 0.1 1.7 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETO03870.1 - 0.074 12.8 0.0 0.24 11.2 0.0 1.9 1 1 1 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF4028 PF13220.1 ETO03871.1 - 0.033 13.8 0.2 0.033 13.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4028) DDE_Tnp_IS66 PF03050.9 ETO03871.1 - 0.082 12.1 1.5 0.1 11.7 1.0 1.5 1 1 0 1 1 1 0 Transposase IS66 family Anticodon_1 PF08264.8 ETO03872.1 - 5e-06 26.3 0.0 6.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA_bind PF01588.15 ETO03872.1 - 6.3e-05 22.7 0.0 0.00013 21.6 0.0 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain PKK PF12474.3 ETO03873.1 - 2.8 7.6 14.8 1.9 8.1 8.3 1.9 2 0 0 2 2 2 0 Polo kinase kinase DUF4337 PF14235.1 ETO03873.1 - 8.8 6.1 6.4 14 5.4 4.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) Atg14 PF10186.4 ETO03874.1 - 0.0079 15.1 0.8 0.0079 15.1 0.6 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF2205 PF10224.4 ETO03874.1 - 0.0096 15.4 1.4 0.013 15.0 1.0 1.2 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) IncA PF04156.9 ETO03874.1 - 0.017 14.6 0.5 0.017 14.6 0.3 1.1 1 0 0 1 1 1 0 IncA protein Bacillus_HBL PF05791.6 ETO03874.1 - 0.024 14.0 0.4 0.031 13.6 0.3 1.1 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) FlxA PF14282.1 ETO03874.1 - 0.04 13.8 9.3 0.052 13.4 6.5 1.2 1 0 0 1 1 1 0 FlxA-like protein End3 PF12761.2 ETO03874.1 - 0.046 13.3 0.9 0.059 13.0 0.6 1.1 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 L31 PF09784.4 ETO03874.1 - 0.054 13.5 0.4 0.082 12.9 0.3 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 ImcF-related_N PF14331.1 ETO03874.1 - 0.068 12.0 0.1 0.068 12.0 0.1 1.1 1 0 0 1 1 1 0 ImcF-related N-terminal domain Vac14_Fab1_bd PF12755.2 ETO03875.1 - 0.004 17.5 0.4 0.01 16.1 0.2 1.6 1 1 1 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 ETO03875.1 - 0.0092 16.2 0.0 0.013 15.7 0.0 1.2 1 0 0 1 1 1 1 HEAT repeats Adaptin_N PF01602.15 ETO03875.1 - 0.012 13.9 0.6 0.019 13.2 0.2 1.5 1 1 0 1 1 1 0 Adaptin N terminal region DUF1678 PF07913.6 ETO03875.1 - 0.023 14.2 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) CENP-I PF07778.6 ETO03875.1 - 0.024 12.8 2.4 0.026 12.7 1.7 1.1 1 0 0 1 1 1 0 Mis6 Cnd1 PF12717.2 ETO03875.1 - 0.043 13.6 0.9 0.056 13.2 0.7 1.2 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 ETO03875.1 - 0.074 13.0 0.3 0.16 11.9 0.2 1.6 1 1 1 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Toxin_trans PF07952.7 ETO03875.1 - 0.12 11.2 0.6 0.13 11.1 0.4 1.1 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain HVSL PF09749.4 ETO03875.1 - 0.12 11.3 0.6 0.17 10.8 0.4 1.3 1 1 0 1 1 1 0 Uncharacterised conserved protein DUF1104 PF06518.6 ETO03875.1 - 0.28 11.3 4.7 0.38 10.8 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) BLVR PF06375.6 ETO03875.1 - 1.8 8.3 5.1 2.1 8.1 3.6 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Holin_LLH PF09682.5 ETO03875.1 - 2.9 8.0 6.7 6.9 6.8 2.5 2.1 2 0 0 2 2 2 0 Phage holin protein (Holin_LLH) DUF3381 PF11861.3 ETO03876.1 - 3.6e-20 72.0 24.4 4.4e-19 68.5 16.9 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3381) RasGEF PF00617.14 ETO03878.1 - 0.0016 18.1 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain FXR1P_C PF12235.3 ETO03878.1 - 0.039 14.0 1.1 0.058 13.4 0.8 1.2 1 0 0 1 1 1 0 Fragile X-related 1 protein C terminal DUF788 PF05620.6 ETO03878.1 - 0.39 10.5 2.4 0.67 9.7 1.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF788) Atrophin-1 PF03154.10 ETO03878.1 - 0.58 8.2 4.9 0.71 7.9 3.4 1.0 1 0 0 1 1 1 0 Atrophin-1 family Adaptin_N PF01602.15 ETO03879.1 - 6.9e-24 84.0 0.2 7.6e-24 83.9 0.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 ETO03879.1 - 0.0044 17.2 0.2 0.42 10.9 0.0 1.9 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 ETO03879.1 - 0.006 16.5 0.3 0.67 10.1 0.1 3.3 3 0 0 3 3 3 1 HEAT repeat MMS19_C PF12460.3 ETO03879.1 - 0.0061 15.3 0.0 0.007 15.1 0.0 1.1 1 0 0 1 1 1 1 RNAPII transcription regulator C-terminal Cnd1 PF12717.2 ETO03879.1 - 0.022 14.5 0.0 0.029 14.2 0.0 1.2 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 DUF4042 PF13251.1 ETO03879.1 - 0.057 12.8 0.2 0.34 10.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4042) HD_assoc PF13286.1 ETO03880.1 - 0.038 14.2 0.6 0.086 13.1 0.1 1.7 1 1 0 2 2 2 0 Phosphohydrolase-associated domain DUF4208 PF13907.1 ETO03880.1 - 0.049 13.8 5.3 2.8 8.2 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4208) DUF445 PF04286.7 ETO03880.1 - 0.11 12.0 2.3 0.13 11.7 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) MitMem_reg PF13012.1 ETO03880.1 - 0.35 10.9 1.8 0.62 10.1 0.3 2.1 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function UCH_1 PF13423.1 ETO03880.1 - 0.59 9.5 4.5 1.9 7.8 3.1 1.7 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF2660 PF10859.3 ETO03880.1 - 1.4 9.1 8.3 2.3 8.4 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2660) DUF972 PF06156.8 ETO03882.1 - 1.8 8.9 10.5 17 5.7 7.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Enkurin PF13864.1 ETO03882.1 - 8.3 6.6 10.1 35 4.6 7.0 2.0 1 1 0 1 1 1 0 Calmodulin-binding DUF2201_N PF13203.1 ETO03883.1 - 2.1 7.4 16.5 2.3 7.2 11.5 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Gag_spuma PF03276.9 ETO03883.1 - 2.8 6.1 13.6 3.1 6.0 9.5 1.1 1 0 0 1 1 1 0 Spumavirus gag protein OATP PF03137.15 ETO03883.1 - 3.3 5.6 4.7 3.3 5.6 3.3 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Plasmodium_Vir PF05795.6 ETO03883.1 - 3.4 6.7 9.8 4.4 6.4 6.8 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF913 PF06025.7 ETO03883.1 - 4.1 6.0 10.1 5 5.7 7.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Herpes_DNAp_acc PF04929.7 ETO03883.1 - 9.2 5.1 15.5 9.9 5.0 10.7 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor zf-MIZ PF02891.15 ETO03884.1 - 6.6e-18 63.9 6.8 6.6e-18 63.9 4.7 3.2 3 1 1 4 4 4 1 MIZ/SP-RING zinc finger zf-MYND PF01753.13 ETO03884.1 - 6.4e-11 41.9 8.3 6.4e-11 41.9 5.8 2.6 2 0 0 2 2 2 1 MYND finger zf-Nse PF11789.3 ETO03884.1 - 0.00032 20.1 3.9 0.0012 18.3 2.7 2.0 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-TFIIB PF13453.1 ETO03884.1 - 0.044 12.9 4.1 1.4 8.1 0.2 2.8 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-Sec23_Sec24 PF04810.10 ETO03884.1 - 0.39 10.3 11.0 0.49 9.9 0.1 3.7 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger PHD PF00628.24 ETO03884.1 - 0.43 10.2 16.3 0.8 9.4 3.0 3.1 2 0 0 2 2 2 0 PHD-finger zf-RanBP PF00641.13 ETO03884.1 - 3.3 6.9 12.4 0.21 10.6 0.5 3.8 3 1 0 3 3 3 0 Zn-finger in Ran binding protein and others dDENN PF03455.14 ETO03885.1 - 4.5e-11 42.6 0.3 9.9e-11 41.5 0.1 1.7 1 1 0 1 1 1 1 dDENN domain DUF3584 PF12128.3 ETO03886.1 - 0.0032 14.9 13.4 0.0036 14.7 9.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DegS PF05384.6 ETO03886.1 - 0.0045 16.2 14.9 0.007 15.5 10.3 1.3 1 0 0 1 1 1 1 Sensor protein DegS Syntaxin_2 PF14523.1 ETO03886.1 - 0.0072 16.3 5.5 0.0072 16.3 3.8 2.1 1 1 1 2 2 2 1 Syntaxin-like protein AAA_32 PF13654.1 ETO03886.1 - 0.02 13.5 8.2 0.028 13.1 5.7 1.1 1 0 0 1 1 1 0 AAA domain bZIP_1 PF00170.16 ETO03886.1 - 0.064 13.2 18.3 0.12 12.3 4.9 2.6 1 1 0 2 2 2 0 bZIP transcription factor Prefoldin_2 PF01920.15 ETO03886.1 - 0.065 13.0 16.1 0.22 11.2 10.4 2.3 1 1 0 1 1 1 0 Prefoldin subunit TPR_MLP1_2 PF07926.7 ETO03886.1 - 0.072 12.8 19.7 0.58 9.9 13.5 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein GAS PF13851.1 ETO03886.1 - 0.094 11.9 15.3 0.13 11.4 10.6 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Fcf1 PF04900.7 ETO03886.1 - 0.14 12.2 0.8 0.25 11.4 0.2 1.7 1 1 0 1 1 1 0 Fcf1 DNA_pol_alpha_N PF12254.3 ETO03886.1 - 0.16 11.8 3.5 0.2 11.4 1.6 1.7 1 1 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal DUF3486 PF11985.3 ETO03886.1 - 0.22 11.5 10.5 0.063 13.3 3.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3486) DUF948 PF06103.6 ETO03886.1 - 0.27 11.1 4.1 2.3 8.1 0.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Seryl_tRNA_N PF02403.17 ETO03886.1 - 0.28 11.1 14.5 1.8 8.6 2.1 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF445 PF04286.7 ETO03886.1 - 0.51 9.8 8.4 0.6 9.5 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) LXG PF04740.7 ETO03886.1 - 0.52 10.0 10.0 1.9 8.1 5.5 2.0 1 1 1 2 2 2 0 LXG domain of WXG superfamily CALCOCO1 PF07888.6 ETO03886.1 - 0.53 8.5 16.5 0.66 8.2 11.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like MxiH PF09392.5 ETO03886.1 - 0.87 10.1 3.9 3.4 8.2 2.7 2.0 1 1 0 1 1 1 0 Type III secretion needle MxiH like THOC7 PF05615.8 ETO03886.1 - 0.87 9.8 22.1 1.4 9.1 6.2 2.1 1 1 1 2 2 2 0 Tho complex subunit 7 Mod_r PF07200.8 ETO03886.1 - 0.92 9.4 17.6 2.9 7.7 4.3 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF1465 PF07323.7 ETO03886.1 - 0.98 8.9 12.2 2.8 7.4 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) Cortex-I_coil PF09304.5 ETO03886.1 - 1.1 9.3 17.5 2.6 8.1 4.1 2.2 1 1 1 2 2 2 0 Cortexillin I, coiled coil Mu-like_Pro PF10123.4 ETO03886.1 - 1.3 8.4 7.0 1.5 8.1 4.9 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein DUF755 PF05501.6 ETO03886.1 - 1.5 8.8 6.9 0.19 11.7 1.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF755) ATG16 PF08614.6 ETO03886.1 - 1.7 8.4 19.7 4.3 7.1 2.9 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DXP_reductoisom PF02670.11 ETO03886.1 - 1.8 9.1 4.7 4.2 7.9 0.9 2.0 1 1 1 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mnd1 PF03962.10 ETO03886.1 - 2 8.0 17.3 0.3 10.7 6.1 2.0 1 1 1 2 2 2 0 Mnd1 family DUF4446 PF14584.1 ETO03886.1 - 2 8.2 12.3 1 9.1 2.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) MbeD_MobD PF04899.7 ETO03886.1 - 2 8.3 11.6 1.3 9.0 4.4 2.6 1 1 1 2 2 2 0 MbeD/MobD like APG6 PF04111.7 ETO03886.1 - 2.1 7.3 20.8 17 4.3 13.7 1.9 1 1 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 ETO03886.1 - 2.2 6.0 10.9 2.6 5.8 7.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_2 PF07716.10 ETO03886.1 - 2.4 8.0 17.7 0.72 9.7 1.8 3.0 2 1 0 2 2 2 0 Basic region leucine zipper FUSC PF04632.7 ETO03886.1 - 3.5 5.9 5.8 4.4 5.6 4.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF342 PF03961.8 ETO03886.1 - 3.5 5.9 13.1 9.7 4.4 9.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Fib_alpha PF08702.5 ETO03886.1 - 3.8 7.6 14.6 3.9 7.6 8.3 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ARD PF03079.9 ETO03886.1 - 4.1 7.3 5.7 6.5 6.6 2.9 1.7 1 1 1 2 2 2 0 ARD/ARD' family DUF4200 PF13863.1 ETO03886.1 - 4.1 7.3 20.1 6.2 6.7 13.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Syntaxin PF00804.20 ETO03886.1 - 6 7.0 13.5 1.8 8.7 1.6 2.4 1 1 1 2 2 2 0 Syntaxin Fzo_mitofusin PF04799.8 ETO03886.1 - 6.7 6.0 11.5 1 8.7 1.8 2.1 1 1 1 2 2 2 0 fzo-like conserved region Sec5 PF15469.1 ETO03886.1 - 7 6.3 10.0 0.53 10.0 1.7 2.0 1 1 1 2 2 2 0 Exocyst complex component Sec5 DivIVA PF05103.8 ETO03886.1 - 8.7 6.4 17.1 76 3.3 11.8 2.3 1 1 0 1 1 1 0 DivIVA protein HAUS6_N PF14661.1 ETO03886.1 - 9.4 5.5 16.0 3.2 7.0 4.7 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus ORC6 PF05460.8 ETO03887.1 - 0.21 10.6 3.5 0.24 10.4 2.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) F-protein PF00469.15 ETO03887.1 - 1.1 8.5 3.7 0.55 9.5 0.5 1.7 1 1 1 2 2 2 0 Negative factor, (F-Protein) or Nef FlgD PF03963.9 ETO03887.1 - 2.9 8.0 0.0 2.9 8.0 0.0 2.6 2 1 0 2 2 2 0 Flagellar hook capping protein - N-terminal region Macoilin PF09726.4 ETO03887.1 - 6.6 4.8 7.9 9.6 4.3 5.5 1.2 1 0 0 1 1 1 0 Transmembrane protein BUD22 PF09073.5 ETO03887.1 - 9.5 5.1 13.5 12 4.8 9.4 1.0 1 0 0 1 1 1 0 BUD22 DUF221 PF02714.10 ETO03888.1 - 1.3e-13 50.5 2.9 1.5e-13 50.3 2.0 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF221 Bd3614-deam PF14439.1 ETO03888.1 - 0.0012 18.6 0.8 0.0017 18.2 0.6 1.2 1 0 0 1 1 1 1 Bd3614-like deaminase DUF4463 PF14703.1 ETO03888.1 - 0.016 15.6 0.0 0.027 14.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4463) Amnionless PF14828.1 ETO03888.1 - 0.4 9.1 4.3 0.77 8.1 2.1 1.8 1 1 1 2 2 2 0 Amnionless CPSF73-100_C PF11718.3 ETO03889.1 - 0.69 9.2 7.4 1 8.6 5.1 1.2 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term DUF2082 PF09855.4 ETO03890.1 - 0.022 14.5 0.2 0.052 13.3 0.0 1.8 2 0 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) ArfGap PF01412.13 ETO03891.1 - 1e-32 112.3 2.4 2.5e-32 111.1 1.7 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF3513 PF12026.3 ETO03891.1 - 0.13 11.7 2.8 0.25 10.8 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) DUF4063 PF13272.1 ETO03892.1 - 0.13 12.1 4.1 0.18 11.5 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4063) Pyr_redox_3 PF13738.1 ETO03894.1 - 0.1 12.6 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MutS_III PF05192.13 ETO03895.1 - 4.3e-13 49.5 0.2 5.3e-13 49.2 0.1 1.2 1 0 0 1 1 1 1 MutS domain III ABC2_membrane PF01061.19 ETO03896.1 - 1.6e-09 37.2 4.2 1.9e-09 37.0 2.9 1.0 1 0 0 1 1 1 1 ABC-2 type transporter STAT_int PF02865.12 ETO03896.1 - 0.044 13.7 0.3 0.18 11.7 0.0 1.8 1 1 1 2 2 2 0 STAT protein, protein interaction domain MtlR PF05068.7 ETO03896.1 - 0.063 12.7 0.3 0.11 11.8 0.1 1.4 1 1 0 1 1 1 0 Mannitol repressor Apq12 PF12716.2 ETO03896.1 - 0.11 12.2 1.5 0.23 11.2 1.1 1.5 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis SAM_2 PF07647.12 ETO03897.1 - 1.8e-08 34.0 0.1 2.7e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO03897.1 - 1.1e-05 25.5 0.1 1.4e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF2340 PF10209.4 ETO03897.1 - 0.047 13.8 0.0 0.056 13.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) Mannosyl_trans3 PF11051.3 ETO03898.1 - 4e-06 26.3 0.5 5.7e-06 25.8 0.2 1.4 1 1 0 1 1 1 1 Mannosyltransferase putative SAM_1 PF00536.25 ETO03900.1 - 7.1e-06 26.0 0.1 1.3e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO03900.1 - 0.0051 16.6 0.0 0.0086 15.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF3631 PF12307.3 ETO03900.1 - 0.096 12.5 1.8 0.11 12.3 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3631) Glyco_tranf_2_4 PF13704.1 ETO03901.1 - 0.011 16.0 0.3 0.014 15.6 0.2 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 2 PARP PF00644.15 ETO03903.1 - 1e-07 31.6 0.1 1.1e-07 31.4 0.1 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain DDE_Tnp_IS66 PF03050.9 ETO03904.1 - 4.8e-75 252.2 0.1 7.7e-75 251.5 0.0 1.4 2 0 0 2 2 2 1 Transposase IS66 family zf-IS66 PF13005.2 ETO03904.1 - 1e-10 41.4 1.8 2.3e-10 40.2 1.2 1.6 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.2 ETO03904.1 - 1.7e-05 25.4 3.6 0.00015 22.3 2.5 2.2 1 1 0 1 1 1 1 Transposase C of IS166 homeodomain Maf1 PF09174.5 ETO03904.1 - 0.0025 17.6 0.0 0.039 13.7 0.0 2.2 2 0 0 2 2 2 1 Maf1 regulator Lectin_N PF03954.9 ETO03904.1 - 0.02 14.2 0.3 0.031 13.6 0.2 1.3 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain TMF_TATA_bd PF12325.3 ETO03904.1 - 0.1 12.3 2.4 0.18 11.5 1.6 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF904 PF06005.7 ETO03904.1 - 0.26 11.5 6.4 0.52 10.6 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) PBP1_TM PF14812.1 ETO03905.1 - 0.13 12.5 4.4 1.6 9.1 0.4 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Exostosin PF03016.10 ETO03906.1 - 0.00043 19.4 0.1 0.0013 17.8 0.0 1.7 1 1 0 1 1 1 1 Exostosin family DUF1162 PF06650.7 ETO03907.1 - 0.0015 17.7 0.0 0.0016 17.6 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1162) Pkinase PF00069.20 ETO03909.1 - 1.7e-23 83.1 0.0 2.1e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO03909.1 - 8.2e-08 31.6 0.0 1.1e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Alpha-amylase PF00128.19 ETO03909.1 - 0.023 14.0 0.1 0.026 13.9 0.1 1.1 1 0 0 1 1 1 0 Alpha amylase, catalytic domain DUF1281 PF06924.6 ETO03909.1 - 0.038 13.3 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) XK-related PF09815.4 ETO03910.1 - 7.8e-09 34.9 4.4 9e-09 34.7 3.0 1.0 1 0 0 1 1 1 1 XK-related protein tRNA-synt_2b PF00587.20 ETO03912.1 - 2.7e-18 66.1 0.0 3e-18 66.0 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Peptidase_S64 PF08192.6 ETO03913.1 - 0.014 13.7 4.7 0.016 13.5 3.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF913 PF06025.7 ETO03913.1 - 0.054 12.2 5.7 0.069 11.8 4.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Hid1 PF12722.2 ETO03913.1 - 0.12 9.9 8.5 0.12 9.9 5.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1510 PF07423.6 ETO03913.1 - 0.23 10.7 16.5 0.29 10.4 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RP-C_C PF11800.3 ETO03913.1 - 0.24 11.0 5.5 0.29 10.7 3.8 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region CKAP2_C PF15297.1 ETO03913.1 - 0.29 9.9 10.5 0.35 9.6 7.3 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus SAPS PF04499.10 ETO03913.1 - 0.62 8.6 8.1 0.69 8.4 5.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ycf1 PF05758.7 ETO03913.1 - 0.86 7.2 7.2 0.97 7.0 5.0 1.0 1 0 0 1 1 1 0 Ycf1 CDC45 PF02724.9 ETO03913.1 - 1.3 6.9 9.3 1.5 6.8 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Packaging_FI PF14000.1 ETO03913.1 - 1.9 8.7 8.9 1.4 9.0 5.3 1.5 1 1 0 1 1 1 0 DNA packaging protein FI TP53IP5 PF15331.1 ETO03913.1 - 1.9 8.3 6.6 2.3 8.0 4.6 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DUF4519 PF15012.1 ETO03913.1 - 2.2 8.2 5.2 4.3 7.3 3.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Sec62 PF03839.11 ETO03913.1 - 2.3 7.5 7.6 3 7.1 5.3 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Daxx PF03344.10 ETO03913.1 - 2.3 6.5 16.6 2.8 6.3 11.5 1.0 1 0 0 1 1 1 0 Daxx Family RNase_H2-Ydr279 PF09468.5 ETO03913.1 - 3.2 6.8 12.3 9.3 5.3 8.5 1.7 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) DUF2146 PF10220.4 ETO03913.1 - 3.3 5.5 9.6 3.9 5.3 6.6 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Zip PF02535.17 ETO03913.1 - 4.1 6.3 5.6 5 6.0 3.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter NOA36 PF06524.7 ETO03913.1 - 4.3 6.4 12.8 5.7 6.1 8.9 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 ETO03913.1 - 4.9 4.9 15.9 5.6 4.7 11.0 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1980 PF09323.5 ETO03913.1 - 7.4 6.2 6.5 14 5.3 3.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) LRR_4 PF12799.2 ETO03914.1 - 9.4e-12 44.2 1.1 1.7e-05 24.3 0.2 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO03914.1 - 7.4e-05 22.4 1.6 0.012 15.3 0.1 2.6 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 ETO03914.1 - 0.01 15.7 0.8 4.1 7.7 0.1 2.9 2 1 0 2 2 2 0 Leucine Rich Repeat DLIC PF05783.6 ETO03915.1 - 1.2e-10 40.6 0.0 1.4e-10 40.4 0.0 1.0 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) Arf PF00025.16 ETO03915.1 - 0.0086 15.3 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO03915.1 - 0.073 12.5 0.0 0.073 12.5 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF2508 PF10704.4 ETO03916.1 - 1.2 9.3 10.3 3.5 7.8 7.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2508) NST1 PF13945.1 ETO03916.1 - 7.2 6.6 12.8 0.94 9.5 2.3 2.1 2 0 0 2 2 2 0 Salt tolerance down-regulator Chordopox_A33R PF05966.7 ETO03917.1 - 0.059 12.1 0.0 0.09 11.5 0.0 1.5 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Mg_trans_NIPA PF05653.9 ETO03917.1 - 0.11 11.4 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Magnesium transporter NIPA Daxx PF03344.10 ETO03918.1 - 0.014 13.9 13.8 0.016 13.7 9.5 1.0 1 0 0 1 1 1 0 Daxx Family ORC6 PF05460.8 ETO03918.1 - 0.028 13.5 1.7 0.031 13.3 1.2 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) BSP_II PF05432.6 ETO03918.1 - 0.029 13.6 8.2 0.035 13.3 5.7 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) BicD PF09730.4 ETO03918.1 - 0.033 12.5 5.2 0.039 12.3 3.6 1.0 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Sigma70_ner PF04546.8 ETO03918.1 - 0.12 11.9 7.1 0.14 11.8 4.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Prog_receptor PF02161.10 ETO03918.1 - 0.22 10.2 6.0 0.24 10.1 4.1 1.0 1 0 0 1 1 1 0 Progesterone receptor Pox_Ag35 PF03286.9 ETO03918.1 - 0.24 10.8 10.4 0.3 10.5 7.2 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein U79_P34 PF03064.11 ETO03918.1 - 0.25 10.8 8.8 0.27 10.6 6.1 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RRN3 PF05327.6 ETO03918.1 - 0.28 9.2 5.2 0.29 9.1 3.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SPX PF03105.14 ETO03918.1 - 0.31 10.7 6.8 0.36 10.5 4.7 1.0 1 0 0 1 1 1 0 SPX domain DUF1014 PF06244.7 ETO03918.1 - 0.42 10.8 2.6 0.67 10.1 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1014) FimP PF09766.4 ETO03918.1 - 0.54 9.2 4.8 0.55 9.2 3.3 1.1 1 0 0 1 1 1 0 Fms-interacting protein Myc_N PF01056.13 ETO03918.1 - 0.62 9.1 7.6 0.73 8.9 5.2 1.1 1 0 0 1 1 1 0 Myc amino-terminal region CobT PF06213.7 ETO03918.1 - 0.65 9.0 13.7 0.83 8.7 9.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FLO_LFY PF01698.11 ETO03918.1 - 1.2 7.8 5.9 1.8 7.3 4.1 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Nop14 PF04147.7 ETO03918.1 - 1.6 6.5 14.1 1.6 6.5 9.8 1.0 1 0 0 1 1 1 0 Nop14-like family UPF0560 PF10577.4 ETO03918.1 - 1.8 6.6 9.7 2.2 6.4 6.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Upf2 PF04050.9 ETO03918.1 - 3 7.5 13.3 5.2 6.8 9.2 1.3 1 0 0 1 1 1 0 Up-frameshift suppressor 2 TRAP_alpha PF03896.11 ETO03918.1 - 3.5 6.5 7.4 3.8 6.4 5.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2722 PF10846.3 ETO03918.1 - 5.6 5.8 12.6 6.6 5.6 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) NOA36 PF06524.7 ETO03918.1 - 6.1 5.9 14.6 7.5 5.7 10.1 1.1 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.7 ETO03918.1 - 6.2 5.9 15.1 7 5.8 10.5 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.8 ETO03918.1 - 6.7 4.3 15.6 7.3 4.2 10.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF1510 PF07423.6 ETO03918.1 - 7.3 5.9 11.7 8.9 5.6 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) G-alpha PF00503.15 ETO03919.1 - 1e-34 119.8 4.2 1.2e-34 119.7 2.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO03919.1 - 0.0016 17.7 0.1 0.0028 16.9 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Wbp11 PF09429.5 ETO03919.1 - 0.073 13.0 12.4 0.12 12.4 8.6 1.3 1 0 0 1 1 1 0 WW domain binding protein 11 V_ATPase_I PF01496.14 ETO03919.1 - 0.45 8.2 2.6 0.45 8.2 1.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 ETO03919.1 - 0.71 10.2 3.7 1.2 9.4 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF4407 PF14362.1 ETO03920.1 - 0.76 8.6 5.7 1.1 8.1 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2262 PF10020.4 ETO03921.1 - 0.1 12.7 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2262) DUF4158 PF13700.1 ETO03923.1 - 4.4e-25 88.0 0.9 9.8e-25 86.9 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4158) Phage_integrase PF00589.17 ETO03923.1 - 2.4e-17 63.1 0.0 5.9e-15 55.3 0.0 2.7 2 1 0 2 2 2 1 Phage integrase family Lipoprotein_3 PF00938.12 ETO03924.1 - 0.0026 17.4 4.0 0.015 15.0 0.8 2.4 1 1 1 2 2 2 1 Lipoprotein FlaF PF07309.6 ETO03924.1 - 0.027 14.3 2.4 0.026 14.3 1.0 1.5 1 1 0 1 1 1 0 Flagellar protein FlaF DASH_Duo1 PF08651.5 ETO03924.1 - 0.051 13.1 2.0 1.6 8.3 0.2 2.5 1 1 1 2 2 2 0 DASH complex subunit Duo1 P4Ha_N PF08336.6 ETO03924.1 - 0.052 13.3 5.9 0.073 12.8 0.5 2.3 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region LZ_Tnp_IS66 PF13007.2 ETO03924.1 - 0.062 13.9 3.7 0.45 11.2 2.6 2.2 1 1 0 1 1 1 0 Transposase C of IS166 homeodomain LemA PF04011.7 ETO03924.1 - 0.1 11.6 1.8 1.1 8.3 0.1 2.3 1 1 1 2 2 2 0 LemA family IFT46_B_C PF12317.3 ETO03924.1 - 0.12 11.7 2.2 0.19 11.0 1.5 1.4 1 1 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal DUF2422 PF10337.4 ETO03924.1 - 0.41 9.3 4.7 0.46 9.2 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) TMPIT PF07851.8 ETO03924.1 - 0.52 9.3 3.4 0.77 8.7 2.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein Atg14 PF10186.4 ETO03924.1 - 0.63 8.9 8.1 0.8 8.5 5.6 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Fib_alpha PF08702.5 ETO03924.1 - 4.1 7.5 8.3 0.89 9.6 2.6 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family AAA_23 PF13476.1 ETO03924.1 - 8.8 6.5 11.8 8.4 6.6 6.8 1.8 1 1 1 2 2 2 0 AAA domain tRNA-synt_1b PF00579.20 ETO03925.1 - 7e-13 48.3 0.1 3.3e-12 46.1 0.0 1.8 1 1 1 2 2 2 1 tRNA synthetases class I (W and Y) DUF2130 PF09903.4 ETO03926.1 - 0.11 11.1 0.1 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) DUF1492 PF07374.6 ETO03926.1 - 0.13 12.3 0.0 0.28 11.3 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1492) SAPS PF04499.10 ETO03926.1 - 0.21 10.1 0.7 4 5.9 0.0 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Rhamnogal_lyase PF06045.6 ETO03927.1 - 0.11 11.7 0.1 0.22 10.8 0.0 1.6 1 1 0 2 2 2 0 Rhamnogalacturonate lyase family HALZ PF02183.13 ETO03928.1 - 0.0034 17.0 4.1 0.0052 16.4 1.8 2.0 1 1 1 2 2 2 1 Homeobox associated leucine zipper HisG_C PF08029.6 ETO03928.1 - 0.021 14.7 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 HisG, C-terminal domain Cep57_CLD_2 PF14197.1 ETO03928.1 - 0.043 13.7 1.1 0.093 12.6 0.5 1.8 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 ADIP PF11559.3 ETO03928.1 - 0.12 12.2 5.5 1.7 8.5 0.1 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF440 PF04269.7 ETO03928.1 - 0.12 12.4 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF440 DUF3450 PF11932.3 ETO03928.1 - 0.14 11.4 3.6 0.11 11.8 1.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Tubulin_3 PF14881.1 ETO03928.1 - 0.2 11.0 1.1 0.35 10.3 0.8 1.5 1 1 0 1 1 1 0 Tubulin domain CENP-H PF05837.7 ETO03928.1 - 0.41 10.8 3.5 0.86 9.8 1.7 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) HAD PF12710.2 ETO03929.1 - 0.0095 16.1 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ATP-synt_ab_N PF02874.18 ETO03931.1 - 2.1e-05 24.6 0.0 4.7e-05 23.5 0.0 1.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain Kelch_6 PF13964.1 ETO03933.1 - 4e-05 23.5 0.1 0.00013 21.9 0.0 1.9 1 0 0 1 1 1 1 Kelch motif Kelch_1 PF01344.20 ETO03933.1 - 0.0048 16.4 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 Kelch motif DEC-1_N PF04625.8 ETO03933.1 - 2 7.0 16.7 2.7 6.5 11.6 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Period_C PF12114.3 ETO03933.1 - 3.4 7.2 9.9 5.3 6.6 6.8 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DAGK_cat PF00781.19 ETO03934.1 - 3e-06 26.6 0.1 1.1e-05 24.8 0.0 1.8 1 1 0 2 2 2 1 Diacylglycerol kinase catalytic domain DUF4588 PF15251.1 ETO03934.1 - 0.076 12.9 2.5 0.065 13.2 0.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4588) ASFV_J13L PF05568.6 ETO03934.1 - 3.5 7.1 4.7 0.68 9.4 0.8 1.6 2 0 0 2 2 2 0 African swine fever virus J13L protein TFIIF_alpha PF05793.7 ETO03934.1 - 4.4 5.5 18.5 5.1 5.3 12.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SAPS PF04499.10 ETO03935.1 - 1.7e-11 43.4 0.3 1.7e-11 43.4 0.2 1.9 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein BUD22 PF09073.5 ETO03935.1 - 4.8 6.1 7.0 6.5 5.7 4.9 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.9 ETO03935.1 - 8.7 4.2 8.4 12 3.8 5.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 ETO03935.1 - 9.7 3.9 14.3 14 3.4 9.9 1.2 1 0 0 1 1 1 0 Nop14-like family ABC_tran PF00005.22 ETO03936.1 - 6.5e-12 45.9 0.7 1.7e-11 44.5 0.1 2.0 2 1 0 2 2 2 1 ABC transporter ABC_tran_2 PF12848.2 ETO03936.1 - 1.6e-08 34.2 1.6 2.3e-08 33.7 1.1 1.2 1 0 0 1 1 1 1 ABC transporter DUF87 PF01935.12 ETO03936.1 - 0.00057 19.7 0.2 0.0013 18.5 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 NACHT PF05729.7 ETO03936.1 - 0.002 17.7 0.0 0.05 13.2 0.0 2.3 1 1 1 2 2 2 1 NACHT domain Miro PF08477.8 ETO03936.1 - 0.0039 17.6 0.0 0.055 13.9 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 ETO03936.1 - 0.004 16.6 2.1 0.0055 16.2 0.6 1.8 1 1 1 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 ETO03936.1 - 0.0056 16.6 0.1 0.033 14.1 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 ETO03936.1 - 0.0064 17.3 0.0 0.033 14.9 0.0 2.1 2 1 1 3 3 2 1 AAA domain AAA PF00004.24 ETO03936.1 - 0.016 15.4 0.0 0.19 11.9 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETO03936.1 - 0.02 15.0 0.0 0.23 11.5 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_21 PF13304.1 ETO03936.1 - 0.022 14.7 3.0 0.04 13.8 0.1 2.2 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 ETO03936.1 - 0.022 14.4 0.1 0.062 13.0 0.0 1.8 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 ETO03936.1 - 0.023 14.5 0.0 0.06 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 ETO03936.1 - 0.027 14.7 0.1 0.082 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 ETO03936.1 - 0.028 13.3 0.0 0.042 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF258 PF03193.11 ETO03936.1 - 0.031 13.4 0.3 0.064 12.4 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 ETO03936.1 - 0.034 14.3 0.1 0.53 10.4 0.0 2.4 1 1 1 2 2 2 0 RNA helicase ArgK PF03308.11 ETO03936.1 - 0.034 12.9 0.0 0.054 12.2 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_10 PF12846.2 ETO03936.1 - 0.04 13.3 0.0 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain SMC_N PF02463.14 ETO03936.1 - 0.053 12.7 0.1 0.086 12.0 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 ETO03936.1 - 0.08 12.3 0.0 0.15 11.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_13 PF13166.1 ETO03936.1 - 0.1 11.0 1.1 0.11 10.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 ETO03936.1 - 0.12 12.3 0.0 0.34 10.8 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase G-alpha PF00503.15 ETO03936.1 - 0.13 10.9 1.1 0.18 10.4 0.4 1.5 1 1 0 1 1 1 0 G-protein alpha subunit AAA_23 PF13476.1 ETO03936.1 - 2.9 8.1 5.5 0.54 10.5 0.2 2.1 1 1 0 2 2 2 0 AAA domain APP_E2 PF12925.2 ETO03937.1 - 0.052 13.1 0.8 0.074 12.6 0.4 1.4 1 1 0 1 1 1 0 E2 domain of amyloid precursor protein Rotavirus_VP1 PF12289.3 ETO03938.1 - 0.00015 21.3 0.1 0.00042 19.8 0.1 1.7 1 0 0 1 1 1 1 Rotavirus VP1 structural protein DUF1623 PF07785.6 ETO03938.1 - 0.37 10.7 6.1 0.11 12.4 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1623) zf-H2C2_2 PF13465.1 ETO03939.1 - 0.08 13.2 0.2 0.21 11.9 0.2 1.7 1 0 0 1 1 1 0 Zinc-finger double domain zf-C2H2 PF00096.21 ETO03939.1 - 1.4 9.4 6.7 1.1 9.7 0.2 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type AT_hook PF02178.14 ETO03939.1 - 1.7 8.5 5.7 5.6 6.9 4.0 1.9 1 0 0 1 1 1 0 AT hook motif zf-C2H2_4 PF13894.1 ETO03939.1 - 1.8 9.0 5.2 6.6 7.3 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Serglycin PF04360.7 ETO03940.1 - 0.18 11.5 3.0 0.29 10.8 2.1 1.5 1 1 0 1 1 1 0 Serglycin RFXA_RFXANK_bdg PF15289.1 ETO03941.1 - 2.4 8.3 7.2 4 7.6 5.0 1.4 1 0 0 1 1 1 0 Regulatory factor X-associated C-terminal binding domain ATP-synt_D PF01813.12 ETO03942.1 - 4.3e-30 104.7 1.5 4.8e-30 104.5 1.0 1.0 1 0 0 1 1 1 1 ATP synthase subunit D GAS PF13851.1 ETO03942.1 - 0.00086 18.5 0.9 0.0012 18.0 0.6 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF4201 PF13870.1 ETO03942.1 - 0.074 12.4 0.2 0.092 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) AIRS_C PF02769.17 ETO03943.1 - 0.0045 16.9 0.0 0.0079 16.2 0.0 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 ETO03943.1 - 0.087 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AIR synthase related protein, N-terminal domain FH2 PF02181.18 ETO03944.1 - 2.3e-24 86.0 0.0 2.7e-24 85.7 0.0 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain HTH_Tnp_Mu_2 PF09039.6 ETO03945.1 - 0.035 13.8 0.1 0.063 13.0 0.1 1.6 1 1 0 1 1 1 0 Mu DNA binding, I gamma subdomain Sigma_1_2 PF03084.9 ETO03946.1 - 0.21 10.1 0.9 0.24 9.9 0.6 1.1 1 0 0 1 1 1 0 Reoviral Sigma1/Sigma2 family DUF3899 PF13038.1 ETO03946.1 - 0.38 10.9 8.2 0.053 13.6 2.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3899) Vmethyltransf_C PF08456.5 ETO03946.1 - 0.53 9.6 5.9 0.63 9.4 4.1 1.1 1 0 0 1 1 1 0 Viral methyltransferase C-terminal MSA_2 PF00985.12 ETO03946.1 - 1.9 8.6 9.3 2.5 8.2 6.4 1.1 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family FAM176 PF14851.1 ETO03946.1 - 3.5 7.3 12.8 0.066 12.8 2.9 1.9 1 1 1 2 2 2 0 FAM176 family DUF4119 PF13494.1 ETO03946.1 - 6.2 6.8 8.8 7.6 6.6 5.2 1.7 1 1 1 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) SpoIIIAH PF12685.2 ETO03946.1 - 9.5 5.6 15.3 11 5.3 10.6 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Actin PF00022.14 ETO03949.1 - 1.2e-14 53.5 0.0 1.6e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Actin DUF1168 PF06658.7 ETO03949.1 - 0.006 16.1 5.9 0.0091 15.5 4.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) NinG PF05766.7 ETO03949.1 - 0.019 14.6 1.0 0.031 14.0 0.7 1.2 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein PilM_2 PF11104.3 ETO03949.1 - 0.062 12.1 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; Xpo1 PF08389.7 ETO03950.1 - 2.9e-15 56.4 0.1 4.5e-15 55.8 0.1 1.3 1 0 0 1 1 1 1 Exportin 1-like protein HYR PF02494.11 ETO03951.1 - 3.8e-05 23.6 0.0 0.00012 22.0 0.0 1.9 1 0 0 1 1 1 1 HYR domain Ldl_recept_a PF00057.13 ETO03951.1 - 5.4e-05 23.0 9.6 5.4e-05 23.0 6.6 1.9 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A DUF4446 PF14584.1 ETO03951.1 - 0.24 11.2 0.1 0.24 11.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) MSG PF02349.10 ETO03951.1 - 0.3 11.0 8.2 0.7 9.9 5.7 1.6 1 0 0 1 1 1 0 Major surface glycoprotein SMI1_KNR4 PF09346.5 ETO03952.1 - 0.035 14.1 2.6 0.072 13.1 1.8 1.7 1 1 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) Kelch_1 PF01344.20 ETO03952.1 - 0.047 13.2 0.1 0.97 9.0 0.0 2.6 2 0 0 2 2 2 0 Kelch motif Kelch_2 PF07646.10 ETO03952.1 - 0.068 12.9 0.2 3.4 7.5 0.0 2.7 2 1 0 2 2 2 0 Kelch motif Kelch_6 PF13964.1 ETO03952.1 - 0.11 12.7 1.1 3.5 7.9 0.2 3.1 2 1 0 2 2 2 0 Kelch motif COesterase PF00135.23 ETO03955.1 - 0.0099 14.6 0.1 0.018 13.8 0.1 1.3 1 0 0 1 1 1 1 Carboxylesterase family Radial_spoke_3 PF06098.6 ETO03956.1 - 0.036 13.0 1.4 0.042 12.8 1.0 1.1 1 0 0 1 1 1 0 Radial spoke protein 3 TPD52 PF04201.10 ETO03956.1 - 0.088 12.5 0.5 0.12 12.1 0.3 1.3 1 0 0 1 1 1 0 Tumour protein D52 family Img2 PF05046.9 ETO03957.1 - 0.078 13.2 0.7 11 6.3 0.0 2.5 2 1 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) IncA PF04156.9 ETO03957.1 - 0.33 10.5 9.6 0.55 9.7 6.7 1.5 1 1 0 1 1 1 0 IncA protein Sin3_corepress PF08295.7 ETO03957.1 - 0.36 10.6 2.8 1.3 8.8 0.1 2.4 2 1 0 2 2 2 0 Sin3 family co-repressor CorA PF01544.13 ETO03957.1 - 0.46 9.4 4.9 0.3 10.0 0.2 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein CDC37_N PF03234.9 ETO03957.1 - 1.6 8.9 9.3 2.2 8.5 6.5 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Cep57_MT_bd PF06657.8 ETO03957.1 - 5.3 7.0 11.0 0.54 10.2 1.0 3.0 3 1 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 NUDE_C PF04880.8 ETO03959.1 - 0.039 14.3 1.0 0.094 13.0 0.4 1.7 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region FYRC PF05965.9 ETO03959.1 - 0.05 13.4 0.1 12 5.7 0.0 2.6 3 0 0 3 3 3 0 F/Y rich C-terminus DUF2959 PF11172.3 ETO03959.1 - 0.063 13.0 3.4 0.077 12.7 0.4 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2959) DUF1510 PF07423.6 ETO03960.1 - 0.0017 17.7 10.7 0.0018 17.6 7.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) DUF2201_N PF13203.1 ETO03960.1 - 0.018 14.2 7.7 0.021 13.9 5.3 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Apt1 PF10351.4 ETO03960.1 - 0.024 13.5 8.0 0.024 13.5 5.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1183 PF06682.7 ETO03960.1 - 0.024 14.2 3.8 0.029 13.9 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DDHD PF02862.12 ETO03960.1 - 0.06 13.1 10.8 0.072 12.8 7.5 1.1 1 0 0 1 1 1 0 DDHD domain Zip PF02535.17 ETO03960.1 - 0.16 10.9 4.0 0.17 10.8 2.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Mem_trans PF03547.13 ETO03960.1 - 0.33 9.1 5.5 0.39 8.9 3.8 1.1 1 0 0 1 1 1 0 Membrane transport protein CDC45 PF02724.9 ETO03960.1 - 0.42 8.5 14.9 0.48 8.4 10.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 ETO03960.1 - 1 6.9 13.8 1.3 6.6 9.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Raftlin PF15250.1 ETO03960.1 - 1.2 7.5 10.7 1.5 7.2 7.4 1.0 1 0 0 1 1 1 0 Raftlin NPR3 PF03666.8 ETO03960.1 - 1.3 7.4 13.1 1.5 7.2 9.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.12 ETO03960.1 - 1.3 7.7 5.5 1.6 7.5 3.8 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.7 ETO03960.1 - 1.6 8.5 11.3 2 8.2 7.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Macoilin PF09726.4 ETO03960.1 - 1.9 6.6 14.9 2.1 6.5 10.3 1.0 1 0 0 1 1 1 0 Transmembrane protein Neur_chan_memb PF02932.11 ETO03960.1 - 2.9 7.7 8.5 3.4 7.4 5.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RCR PF12273.3 ETO03960.1 - 3.4 8.2 8.7 5.2 7.6 6.1 1.2 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF4614 PF15391.1 ETO03960.1 - 4.5 7.0 12.0 5.6 6.6 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Tim54 PF11711.3 ETO03960.1 - 5.6 5.4 11.0 6.8 5.1 7.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 AIF_C PF14721.1 ETO03960.1 - 5.7 7.2 10.0 9.4 6.4 6.9 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Paramyxo_C PF01692.13 ETO03960.1 - 6.2 6.3 10.3 8.4 5.9 7.1 1.2 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c Dsh_C PF12316.3 ETO03960.1 - 9.5 6.2 15.0 12 5.8 10.4 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal TPR_7 PF13176.1 ETO03961.1 - 3.6e-06 26.3 0.5 0.19 11.6 0.0 3.4 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO03961.1 - 0.00014 21.4 0.4 1.4 9.0 0.1 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO03961.1 - 0.00016 21.5 1.7 0.76 9.7 0.0 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO03961.1 - 0.017 15.7 1.5 0.89 10.3 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETO03961.1 - 0.023 14.3 0.1 0.36 10.5 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 ETO03961.1 - 0.033 13.8 3.2 1.6 8.4 0.3 2.9 1 1 1 2 2 2 0 TPR repeat FAT PF02259.18 ETO03961.1 - 0.038 12.9 2.9 0.049 12.6 1.3 1.6 1 1 0 2 2 2 0 FAT domain TPR_8 PF13181.1 ETO03961.1 - 0.04 13.7 0.2 1.7 8.6 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat RGS-like PF09128.6 ETO03961.1 - 0.04 13.4 0.5 0.046 13.2 0.4 1.1 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain TPR_9 PF13371.1 ETO03961.1 - 0.1 12.4 0.1 3.9 7.3 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat AMP-binding_C_2 PF14535.1 ETO03961.1 - 0.12 12.4 1.0 0.2 11.7 0.1 1.8 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain HHH_8 PF14716.1 ETO03961.1 - 0.15 12.2 0.5 80 3.5 0.0 3.1 3 0 0 3 3 3 0 Helix-hairpin-helix domain CCDC74_C PF14917.1 ETO03962.1 - 1.6e-05 24.9 0.1 2.4e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Coiled coil protein 74, C terminal SlyX PF04102.7 ETO03962.1 - 0.047 14.0 0.0 0.086 13.2 0.0 1.4 1 0 0 1 1 1 0 SlyX LepA_C PF06421.7 ETO03962.1 - 7.4 6.5 6.9 17 5.3 2.8 2.1 1 1 0 2 2 2 0 GTP-binding protein LepA C-terminus Adaptin_N PF01602.15 ETO03964.1 - 3.6e-27 94.9 0.6 4e-27 94.7 0.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 ETO03964.1 - 4.1e-09 36.5 0.1 1.2e-08 34.9 0.0 1.6 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 ETO03964.1 - 1.4e-05 25.2 0.5 0.16 12.2 0.1 2.5 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 ETO03964.1 - 8.2e-05 22.3 3.4 0.026 14.5 0.0 3.6 4 0 0 4 4 4 1 HEAT repeat Arm PF00514.18 ETO03964.1 - 0.00014 21.5 1.1 1.6 8.6 0.0 3.4 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat MMS19_C PF12460.3 ETO03964.1 - 0.0058 15.4 0.4 0.008 14.9 0.3 1.1 1 0 0 1 1 1 1 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.1 ETO03964.1 - 0.021 15.2 0.2 11 6.6 0.0 3.0 2 1 1 3 3 3 0 HEAT-like repeat Nipped-B_C PF12830.2 ETO03964.1 - 0.083 12.5 0.0 2.5 7.7 0.0 2.3 2 1 0 2 2 2 0 Sister chromatid cohesion C-terminus ABC2_membrane PF01061.19 ETO03965.1 - 1e-06 28.0 4.1 1e-06 28.0 2.8 2.1 2 0 0 2 2 2 1 ABC-2 type transporter TRAM_LAG1_CLN8 PF03798.11 ETO03965.1 - 0.0022 17.5 1.8 0.0022 17.5 1.2 1.5 2 0 0 2 2 2 1 TLC domain Sigma_reg_N PF13800.1 ETO03965.1 - 0.03 14.3 1.1 0.072 13.1 0.8 1.6 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DNA_pol3_beta_3 PF02768.10 ETO03965.1 - 0.096 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III beta subunit, C-terminal domain Ldh_1_C PF02866.13 ETO03965.1 - 0.11 12.2 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain EAP30 PF04157.11 ETO03966.1 - 0.00082 18.5 1.5 0.001 18.3 0.6 1.4 1 1 0 1 1 1 1 EAP30/Vps36 family RmuC PF02646.11 ETO03966.1 - 0.0077 15.1 1.9 0.0086 14.9 1.3 1.2 1 0 0 1 1 1 1 RmuC family Fmp27_WPPW PF10359.4 ETO03966.1 - 0.028 12.8 6.5 0.029 12.7 4.5 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DivIVA PF05103.8 ETO03966.1 - 0.039 13.9 3.9 0.039 13.9 2.7 1.9 1 1 1 2 2 2 0 DivIVA protein Streptin-Immun PF11083.3 ETO03966.1 - 0.041 13.8 4.1 0.072 13.0 2.8 1.5 1 1 0 1 1 1 0 Lantibiotic streptin immunity protein DUF883 PF05957.8 ETO03966.1 - 0.049 14.0 4.3 0.64 10.4 1.4 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Endotoxin_N PF03945.9 ETO03966.1 - 0.07 12.5 1.2 0.075 12.4 0.8 1.0 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain Bac_GDH PF05088.7 ETO03966.1 - 0.1 9.9 4.9 0.11 9.9 3.4 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase IncA PF04156.9 ETO03966.1 - 0.11 12.0 6.0 0.14 11.7 4.1 1.1 1 0 0 1 1 1 0 IncA protein Hemerythrin PF01814.18 ETO03966.1 - 0.15 12.1 4.6 0.19 11.8 3.2 1.2 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain DUF1664 PF07889.7 ETO03966.1 - 0.17 11.6 3.4 0.2 11.4 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF948 PF06103.6 ETO03966.1 - 0.18 11.6 2.8 0.36 10.7 1.4 1.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Nup54 PF13874.1 ETO03966.1 - 0.22 11.1 6.4 0.29 10.8 4.4 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 LETM1 PF07766.8 ETO03966.1 - 0.24 10.3 4.3 0.29 10.1 3.0 1.0 1 0 0 1 1 1 0 LETM1-like protein DUF3508 PF12018.3 ETO03966.1 - 0.25 10.3 3.5 0.37 9.7 2.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3508) DUF972 PF06156.8 ETO03966.1 - 0.4 11.0 8.1 0.48 10.7 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) RNA_pol_3_Rpc31 PF11705.3 ETO03966.1 - 0.41 10.5 7.5 0.46 10.3 5.2 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Occludin_ELL PF07303.8 ETO03966.1 - 0.42 11.3 7.1 0.94 10.2 3.5 1.9 1 1 1 2 2 2 0 Occludin homology domain APG6 PF04111.7 ETO03966.1 - 0.51 9.3 7.9 0.62 9.0 5.5 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 PRKCSH-like PF12999.2 ETO03966.1 - 0.54 9.8 3.1 0.7 9.4 2.1 1.1 1 0 0 1 1 1 0 Glucosidase II beta subunit-like DUF848 PF05852.6 ETO03966.1 - 0.66 9.8 7.1 0.84 9.4 4.9 1.1 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF719 PF05334.8 ETO03966.1 - 0.81 9.6 3.5 1.1 9.2 2.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF719) zf-C4H2 PF10146.4 ETO03966.1 - 0.87 9.5 6.9 0.92 9.4 4.8 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein V_ATPase_I PF01496.14 ETO03966.1 - 1 7.1 5.8 1.2 6.9 4.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family COG2 PF06148.6 ETO03966.1 - 1.4 8.8 7.0 0.96 9.3 3.9 1.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 GvpK PF05121.7 ETO03966.1 - 2.3 8.0 7.3 1.8 8.4 1.0 2.0 1 1 1 2 2 2 0 Gas vesicle protein K DUF1539 PF07560.6 ETO03968.1 - 0.045 13.6 0.4 0.077 12.8 0.0 1.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) Thermopsin PF05317.6 ETO03968.1 - 0.56 9.0 3.2 0.63 8.9 2.2 1.2 1 0 0 1 1 1 0 Thermopsin MULE PF10551.4 ETO03969.1 - 0.14 12.3 0.2 0.36 11.0 0.1 1.7 1 1 1 2 2 2 0 MULE transposase domain Nop52 PF05997.7 ETO03970.1 - 0.093 12.1 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Nucleolar protein,Nop52 Lentiviral_Tat PF02998.9 ETO03971.1 - 0.19 11.5 0.5 0.39 10.5 0.0 1.8 2 0 0 2 2 2 0 Lentiviral Tat protein 60KD_IMP PF02096.15 ETO03971.1 - 0.35 10.4 3.6 0.74 9.4 2.5 1.8 1 1 0 1 1 1 0 60Kd inner membrane protein RyR PF02026.11 ETO03972.1 - 0.13 12.2 1.8 0.26 11.3 0.5 1.9 2 0 0 2 2 2 0 RyR domain Nucleoside_tran PF01733.13 ETO03972.1 - 0.14 11.2 0.5 0.16 11.1 0.4 1.1 1 0 0 1 1 1 0 Nucleoside transporter Mem_trans PF03547.13 ETO03972.1 - 0.34 9.1 1.8 0.41 8.8 1.3 1.0 1 0 0 1 1 1 0 Membrane transport protein eIF3_subunit PF08597.5 ETO03973.1 - 0.00015 21.4 3.6 0.00015 21.4 2.5 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Pox_Ag35 PF03286.9 ETO03973.1 - 0.0023 17.4 3.0 0.0026 17.3 2.1 1.0 1 0 0 1 1 1 1 Pox virus Ag35 surface protein Miro PF08477.8 ETO03973.1 - 0.015 15.7 0.2 0.02 15.4 0.1 1.4 1 1 0 1 1 1 0 Miro-like protein RP-C_C PF11800.3 ETO03973.1 - 0.11 12.2 2.1 0.12 12.1 1.5 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region NPR3 PF03666.8 ETO03973.1 - 0.44 9.0 4.9 0.47 8.9 3.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2058 PF09831.4 ETO03973.1 - 0.65 9.8 6.9 0.78 9.6 4.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) NST1 PF13945.1 ETO03973.1 - 1.7 8.6 11.4 2.2 8.3 7.9 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Striatin PF08232.7 ETO03973.1 - 3.2 8.0 8.9 4.1 7.7 6.2 1.1 1 0 0 1 1 1 0 Striatin family RFXA_RFXANK_bdg PF15289.1 ETO03973.1 - 3.7 7.7 8.8 4.8 7.3 6.1 1.1 1 0 0 1 1 1 0 Regulatory factor X-associated C-terminal binding domain DUF1754 PF08555.5 ETO03973.1 - 4 8.1 17.2 5.3 7.6 11.9 1.2 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) GAGA_bind PF06217.7 ETO03973.1 - 4.7 7.0 10.7 5.8 6.7 7.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family TFIIF_alpha PF05793.7 ETO03973.1 - 5.5 5.2 12.5 6.5 4.9 8.7 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Dynamitin PF04912.9 ETO03974.1 - 3.7e-08 32.5 9.9 4.4e-08 32.3 6.8 1.0 1 0 0 1 1 1 1 Dynamitin PilJ PF13675.1 ETO03974.1 - 0.002 18.4 1.3 0.0029 17.9 0.9 1.3 1 1 0 1 1 1 1 Type IV pili methyl-accepting chemotaxis transducer N-term CITED PF04487.7 ETO03974.1 - 0.0069 16.6 0.0 0.0084 16.3 0.0 1.1 1 0 0 1 1 1 1 CITED DUF4335 PF14233.1 ETO03974.1 - 0.043 13.2 0.3 0.043 13.2 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4335) EMP24_GP25L PF01105.19 ETO03974.1 - 0.046 13.4 4.1 0.03 14.0 1.5 1.7 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD HEPN PF05168.9 ETO03974.1 - 0.059 13.2 0.4 0.12 12.2 0.2 1.7 1 1 0 1 1 1 0 HEPN domain DNA_repr_REX1B PF14966.1 ETO03974.1 - 0.29 11.5 4.9 0.94 9.8 1.0 2.2 1 1 1 2 2 2 0 DNA repair REX1-B N_NLPC_P60 PF12912.2 ETO03974.1 - 0.33 11.0 3.0 0.43 10.6 0.5 2.1 1 1 1 2 2 2 0 NLPC_P60 stabilising domain, N term DUF3959 PF13105.1 ETO03974.1 - 2.2 7.5 5.5 1.3 8.3 2.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3959) Fib_alpha PF08702.5 ETO03974.1 - 4.6 7.3 8.2 6.6 6.8 1.0 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FMN_bind PF04205.9 ETO03975.1 - 0.029 14.5 0.4 0.044 13.9 0.3 1.3 1 0 0 1 1 1 0 FMN-binding domain Ribosomal_L24e PF01246.15 ETO03975.1 - 0.068 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L24e polyprenyl_synt PF00348.12 ETO03976.1 - 0.033 13.0 0.1 0.042 12.6 0.1 1.1 1 0 0 1 1 1 0 Polyprenyl synthetase MreB_Mbl PF06723.8 ETO03977.1 - 0.08 11.5 1.4 0.1 11.1 1.0 1.1 1 0 0 1 1 1 0 MreB/Mbl protein DUF2217 PF10265.4 ETO03977.1 - 0.13 10.9 3.2 0.14 10.8 2.2 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) EST1 PF10374.4 ETO03977.1 - 0.27 11.2 2.1 0.4 10.6 1.2 1.5 1 1 0 1 1 1 0 Telomerase activating protein Est1 FliE PF02049.13 ETO03977.1 - 0.36 10.8 8.3 0.32 11.0 1.9 2.2 2 0 0 2 2 2 0 Flagellar hook-basal body complex protein FliE Serinc PF03348.10 ETO03977.1 - 1.3 7.6 5.6 1.5 7.4 3.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2052 PF09747.4 ETO03977.1 - 2.3 8.1 13.5 3.4 7.5 9.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) FlaG PF03646.10 ETO03977.1 - 9.7 6.3 14.4 11 6.2 2.8 2.2 2 0 0 2 2 2 0 FlaG protein Cullin PF00888.17 ETO03978.1 - 8.7e-35 120.3 6.7 1e-34 120.0 4.6 1.0 1 0 0 1 1 1 1 Cullin family DUF4083 PF13314.1 ETO03978.1 - 0.069 12.9 0.2 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Glutaredoxin2_C PF04399.8 ETO03978.1 - 0.12 11.9 0.8 0.15 11.6 0.5 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Aph-1 PF06105.7 ETO03979.1 - 0.42 9.8 2.6 4.1 6.5 0.9 2.0 2 0 0 2 2 2 0 Aph-1 protein zf-H2C2_2 PF13465.1 ETO03980.1 - 8.3e-07 28.9 7.8 6.6e-05 22.9 0.7 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-BED PF02892.10 ETO03980.1 - 0.0024 17.5 10.5 0.31 10.8 1.8 2.7 1 1 1 2 2 2 2 BED zinc finger zf-C2H2_4 PF13894.1 ETO03980.1 - 0.01 16.1 8.3 0.74 10.2 2.0 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 ETO03980.1 - 0.18 12.1 7.5 5.1 7.6 1.6 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 ETO03980.1 - 4.6 7.4 12.0 2 8.5 0.1 2.9 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF605 PF04652.11 ETO03981.1 - 0.47 9.7 26.1 0.52 9.6 18.1 1.0 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 ETO03981.1 - 0.86 7.7 27.1 1.1 7.4 18.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1675 PF07897.6 ETO03981.1 - 6.2 6.5 9.8 8.1 6.2 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) TAXi_N PF14543.1 ETO03982.1 - 0.024 14.5 0.9 0.044 13.7 0.6 1.4 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal Toxin_17 PF08086.6 ETO03982.1 - 0.11 12.6 1.4 0.2 11.7 0.2 1.9 2 0 0 2 2 2 0 Ergtoxin family DUF1840 PF08895.6 ETO03984.1 - 0.023 14.7 0.4 0.038 13.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) DUF2029 PF09594.5 ETO03985.1 - 0.0092 15.5 1.6 0.012 15.1 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2029) YfhO PF09586.5 ETO03985.1 - 0.016 13.2 2.6 0.02 12.9 1.8 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Pho86 PF11124.3 ETO03985.1 - 0.12 11.3 1.0 0.17 10.8 0.7 1.2 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 TspO_MBR PF03073.10 ETO03985.1 - 0.14 11.7 6.5 0.19 11.2 4.5 1.2 1 0 0 1 1 1 0 TspO/MBR family Shikimate_DH PF01488.15 ETO03986.1 - 0.0002 21.4 0.2 0.0061 16.6 0.1 2.1 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase OCD_Mu_crystall PF02423.10 ETO03986.1 - 0.019 13.7 0.1 0.047 12.4 0.1 1.8 1 1 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family DASH_Dad1 PF08649.5 ETO03986.1 - 0.023 14.4 0.1 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 DASH complex subunit Dad1 DAHP_synth_2 PF01474.11 ETO03986.1 - 0.031 12.6 0.0 0.052 11.9 0.0 1.4 1 1 0 1 1 1 0 Class-II DAHP synthetase family Pkinase PF00069.20 ETO03987.1 - 2.5e-13 49.7 0.1 3.1e-13 49.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO03987.1 - 2.4e-07 30.1 0.0 2.7e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO03987.1 - 8.5e-05 21.7 0.1 0.00012 21.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 ETO03987.1 - 0.022 14.3 0.1 0.028 14.0 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 ETO03987.1 - 0.032 13.5 0.1 0.051 12.9 0.1 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 ETO03987.1 - 0.033 13.9 0.1 0.042 13.5 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family UCH PF00443.24 ETO03988.1 - 2.8e-10 39.7 0.7 4e-10 39.2 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO03988.1 - 0.15 11.4 3.1 0.081 12.3 0.5 1.7 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase CRF-BP PF05428.6 ETO03989.1 - 0.022 13.6 0.7 0.028 13.2 0.5 1.1 1 0 0 1 1 1 0 Corticotropin-releasing factor binding protein (CRF-BP) Lambda_Bor PF06291.6 ETO03989.1 - 1.6 8.6 6.4 3.9 7.4 1.7 2.5 2 1 0 2 2 2 0 Bor protein Carboxyl_trans PF01039.17 ETO03990.1 - 6e-37 127.1 0.0 7.4e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain DUF4557 PF15101.1 ETO03991.1 - 0.024 14.4 1.2 0.033 14.0 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) COX17 PF05051.8 ETO03991.1 - 0.05 13.6 1.5 0.12 12.4 1.0 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Phage_GP20 PF06810.6 ETO03991.1 - 0.099 12.0 7.6 0.18 11.2 5.3 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 TMEM51 PF15345.1 ETO03992.1 - 0.05 13.2 7.3 0.067 12.8 5.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 DRIM PF07539.7 ETO03992.1 - 0.052 12.9 3.4 0.033 13.6 0.9 1.7 2 0 0 2 2 2 0 Down-regulated in metastasis MRL1 PF13003.2 ETO03992.1 - 1.6 8.5 5.4 0.89 9.3 1.2 2.1 2 1 0 2 2 2 0 Ribosomal protein L1 Glyco_transf_8 PF01501.15 ETO03994.1 - 0.0042 16.4 0.7 0.0049 16.2 0.4 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 Draxin PF15550.1 ETO03994.1 - 0.79 9.3 12.5 0.94 9.0 8.6 1.1 1 0 0 1 1 1 0 Draxin CDC45 PF02724.9 ETO03994.1 - 1.5 6.7 14.9 1.8 6.5 10.3 1.0 1 0 0 1 1 1 0 CDC45-like protein RVT_1 PF00078.22 ETO03995.1 - 2.3e-48 164.4 0.8 2.3e-48 164.4 0.6 1.8 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) SAM_1 PF00536.25 ETO03996.1 - 7.7e-12 45.2 1.7 7.7e-12 45.2 1.1 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO03996.1 - 2.8e-11 43.0 0.7 4.5e-11 42.4 0.5 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pox_F12L PF03337.8 ETO03996.1 - 0.00019 19.5 0.2 0.00024 19.1 0.1 1.1 1 0 0 1 1 1 1 Poxvirus F12L protein PAP_central PF04928.12 ETO03996.1 - 0.076 11.8 0.8 0.089 11.5 0.6 1.1 1 0 0 1 1 1 0 Poly(A) polymerase central domain RAB3GAP2_N PF14655.1 ETO03996.1 - 0.33 9.9 3.0 0.15 11.0 0.1 1.8 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF342 PF03961.8 ETO03996.1 - 0.44 8.9 3.7 0.52 8.6 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) C2 PF00168.25 ETO03997.1 - 8.3e-09 35.1 0.0 1.9e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 C2 domain TPR_11 PF13414.1 ETO03998.1 - 1.2e-10 40.8 12.1 7.3e-07 28.7 2.6 2.0 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 ETO03998.1 - 2.8e-07 29.9 1.6 0.0005 19.7 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO03998.1 - 1.2e-06 27.9 3.1 0.0015 18.0 0.8 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETO03998.1 - 6.4e-06 25.9 0.3 8.3e-06 25.5 0.2 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO03998.1 - 8.8e-05 23.0 2.4 0.00013 22.4 1.7 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO03998.1 - 0.00083 19.2 3.2 0.049 13.5 0.2 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO03998.1 - 0.0031 17.5 2.4 0.0046 17.0 1.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO03998.1 - 0.034 14.4 3.4 0.045 14.0 1.4 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat NYD-SP12_N PF15015.1 ETO03998.1 - 0.05 11.8 0.8 0.057 11.6 0.1 1.3 1 1 0 1 1 1 0 Spermatogenesis-associated, N-terminal DUF3856 PF12968.2 ETO03998.1 - 0.16 11.8 0.7 1.8 8.4 0.5 2.0 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) TPR_14 PF13428.1 ETO03998.1 - 0.19 12.4 2.1 3.2 8.6 0.6 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat Mob1_phocein PF03637.12 ETO03999.1 - 1.4e-27 96.5 9.5 1.7e-27 96.2 6.6 1.1 1 0 0 1 1 1 1 Mob1/phocein family G10 PF01125.12 ETO04000.1 - 0.00059 19.4 0.0 0.00065 19.2 0.0 1.2 1 0 0 1 1 1 1 G10 protein RRM_1 PF00076.17 ETO04002.1 - 1.4e-29 101.4 1.1 8.8e-16 57.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO04002.1 - 2.6e-21 75.3 0.2 5.7e-12 45.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO04002.1 - 5.7e-08 32.4 0.9 0.00012 21.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 ETO04003.1 - 1.4e-35 119.8 14.9 8.4e-12 44.4 1.0 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat PD40 PF07676.7 ETO04003.1 - 0.0015 18.1 0.0 0.53 10.0 0.0 2.7 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Apc4_WD40 PF12894.2 ETO04003.1 - 0.012 15.1 0.0 22 4.6 0.0 4.4 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain OAR PF03826.12 ETO04003.1 - 0.083 12.4 0.8 0.27 10.7 0.6 1.9 1 0 0 1 1 1 0 OAR domain FAM163 PF15069.1 ETO04004.1 - 0.21 12.1 3.8 0.57 10.7 2.5 1.8 1 1 1 2 2 2 0 FAM163 family Aha1_N PF09229.6 ETO04006.1 - 0.00045 20.0 0.7 0.00063 19.5 0.5 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal D123 PF07065.9 ETO04007.1 - 2.5e-14 53.0 0.7 6e-14 51.8 0.5 1.5 1 1 0 1 1 1 1 D123 DUF4343 PF14243.1 ETO04007.1 - 0.008 16.0 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4343) Pkinase PF00069.20 ETO04008.1 - 7.6e-21 74.4 0.3 9e-21 74.1 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO04008.1 - 2.3e-07 30.1 0.3 2.6e-07 30.0 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO04008.1 - 0.00012 21.2 0.4 0.00013 21.1 0.3 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 ETO04008.1 - 0.0097 15.4 0.5 0.012 15.2 0.4 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 ETO04008.1 - 0.026 13.8 0.3 0.035 13.4 0.2 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 ETO04008.1 - 0.029 14.1 0.0 0.037 13.7 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Tau95 PF09734.4 ETO04008.1 - 0.11 11.8 0.1 0.12 11.6 0.0 1.0 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit IPK PF03770.11 ETO04008.1 - 0.12 11.9 4.5 0.41 10.2 3.1 1.8 1 1 0 1 1 1 0 Inositol polyphosphate kinase DUF4355 PF14265.1 ETO04008.1 - 0.14 12.0 7.0 0.22 11.4 4.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4355) DUF3155 PF11352.3 ETO04008.1 - 0.18 12.0 1.1 0.24 11.6 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3155) SR-25 PF10500.4 ETO04008.1 - 0.58 9.5 7.0 0.7 9.3 4.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BLVR PF06375.6 ETO04008.1 - 6 6.6 9.6 8.5 6.1 6.7 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Pkinase PF00069.20 ETO04009.1 - 1.7e-09 37.2 0.0 5.9e-09 35.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain RGS PF00615.14 ETO04009.1 - 1.8e-06 28.0 0.8 3.1e-06 27.2 0.5 1.6 1 1 0 1 1 1 1 Regulator of G protein signaling domain Pkinase_Tyr PF07714.12 ETO04009.1 - 0.0038 16.3 0.0 0.0072 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase G-alpha PF00503.15 ETO04010.1 - 1.4e-53 181.9 9.6 1.7e-53 181.7 6.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO04010.1 - 2.9e-10 39.6 0.8 1.3e-06 27.7 0.1 2.5 1 1 1 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO04010.1 - 0.033 13.6 0.2 0.081 12.3 0.1 1.6 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain TPK_catalytic PF04263.11 ETO04010.1 - 0.066 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain Cullin PF00888.17 ETO04011.1 - 3.7e-26 91.8 2.2 3.9e-26 91.7 1.5 1.0 1 0 0 1 1 1 1 Cullin family Dicty_REP PF05086.7 ETO04012.1 - 0.003 15.3 7.3 0.0035 15.1 5.1 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein UPF0560 PF10577.4 ETO04012.1 - 0.012 13.9 2.9 0.015 13.6 2.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF775 PF05603.7 ETO04012.1 - 0.033 13.7 1.1 0.044 13.2 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Tir_receptor_C PF07489.6 ETO04012.1 - 0.15 11.7 3.8 0.24 11.1 2.6 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus DUF2052 PF09747.4 ETO04012.1 - 0.54 10.1 6.7 0.7 9.7 4.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.7 ETO04012.1 - 3.8 7.3 8.1 5.1 6.9 5.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF572 PF04502.8 ETO04012.1 - 5.8 6.0 12.4 5 6.2 7.8 1.3 1 1 1 2 2 2 0 Family of unknown function (DUF572) B56 PF01603.15 ETO04013.1 - 5.7e-18 64.7 0.2 6.2e-18 64.5 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) PPP4R2 PF09184.6 ETO04014.1 - 0.91 9.0 15.9 1.3 8.4 11.0 1.2 1 0 0 1 1 1 0 PPP4R2 CRT10 PF08728.5 ETO04014.1 - 0.93 7.4 8.6 1.1 7.1 6.0 1.0 1 0 0 1 1 1 0 CRT10 DUF853 PF05872.7 ETO04014.1 - 1.3 7.2 6.3 1.5 7.1 4.4 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) FLO_LFY PF01698.11 ETO04014.1 - 2.2 7.0 14.5 2.6 6.7 10.1 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Membralin PF09746.4 ETO04014.1 - 4.9 6.0 7.7 6 5.8 5.3 1.1 1 0 0 1 1 1 0 Tumour-associated protein Macoilin PF09726.4 ETO04014.1 - 8.6 4.5 20.1 11 4.2 14.0 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF4096 PF13340.1 ETO04015.1 - 1.6e-19 69.5 0.2 3.1e-19 68.6 0.1 1.4 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.16 ETO04015.1 - 3.9e-19 69.0 0.1 1e-18 67.6 0.0 1.6 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.1 ETO04015.1 - 1.1e-18 67.1 0.0 2.5e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.1 ETO04015.1 - 5e-11 42.5 0.1 7.9e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.1 ETO04015.1 - 2.1e-08 33.9 0.0 3.9e-08 33.0 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF1510 PF07423.6 ETO04016.1 - 0.0001 21.7 14.8 0.00012 21.4 10.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Adaptin_binding PF10199.4 ETO04016.1 - 0.00072 19.8 8.2 0.00089 19.5 5.7 1.2 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 DUF2722 PF10846.3 ETO04016.1 - 0.00081 18.5 8.9 0.00095 18.2 6.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) SPX PF03105.14 ETO04016.1 - 0.0011 18.7 7.0 0.0013 18.5 4.9 1.1 1 0 0 1 1 1 1 SPX domain Ycf1 PF05758.7 ETO04016.1 - 0.0019 16.0 3.4 0.002 15.9 2.4 1.0 1 0 0 1 1 1 1 Ycf1 SID-1_RNA_chan PF13965.1 ETO04016.1 - 0.0046 15.1 1.3 0.0052 15.0 0.9 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 DDHD PF02862.12 ETO04016.1 - 0.0057 16.4 4.0 0.007 16.1 2.8 1.2 1 0 0 1 1 1 1 DDHD domain Cwf_Cwc_15 PF04889.7 ETO04016.1 - 0.0063 16.2 14.6 0.0071 16.0 10.1 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Menin PF05053.8 ETO04016.1 - 0.0074 14.5 4.8 0.0082 14.3 3.3 1.0 1 0 0 1 1 1 1 Menin DUF913 PF06025.7 ETO04016.1 - 0.01 14.5 1.4 0.011 14.4 1.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) BUD22 PF09073.5 ETO04016.1 - 0.015 14.3 18.0 0.019 14.0 12.5 1.1 1 0 0 1 1 1 0 BUD22 Vfa1 PF08432.5 ETO04016.1 - 0.028 14.4 11.9 0.044 13.8 8.2 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Zip PF02535.17 ETO04016.1 - 0.032 13.2 1.9 0.04 12.9 1.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter FYDLN_acid PF09538.5 ETO04016.1 - 0.1 13.1 24.5 0.23 12.0 16.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Trypan_PARP PF05887.6 ETO04016.1 - 0.11 12.2 3.5 0.16 11.7 2.4 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF2201_N PF13203.1 ETO04016.1 - 0.14 11.2 3.9 0.16 11.1 2.7 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.9 ETO04016.1 - 0.25 9.3 17.8 0.33 8.9 12.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.9 ETO04016.1 - 0.26 10.7 19.3 0.41 10.1 13.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Raftlin PF15250.1 ETO04016.1 - 0.31 9.5 6.4 0.39 9.1 4.5 1.1 1 0 0 1 1 1 0 Raftlin RNA_pol_3_Rpc31 PF11705.3 ETO04016.1 - 0.31 10.9 21.2 0.49 10.3 14.7 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 FLO_LFY PF01698.11 ETO04016.1 - 0.34 9.7 7.2 0.4 9.4 5.0 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein DNA_pol_phi PF04931.8 ETO04016.1 - 0.34 8.6 18.5 0.45 8.2 12.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Gag_spuma PF03276.9 ETO04016.1 - 0.36 9.0 2.7 0.44 8.8 1.9 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DUF2457 PF10446.4 ETO04016.1 - 0.37 9.4 30.6 0.54 8.9 21.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 ETO04016.1 - 0.48 8.8 25.2 0.65 8.4 17.5 1.1 1 0 0 1 1 1 0 Daxx Family DUF2076 PF09849.4 ETO04016.1 - 0.5 10.3 16.6 0.62 10.0 11.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) CobT PF06213.7 ETO04016.1 - 0.57 9.2 23.9 0.78 8.8 16.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 ETO04016.1 - 0.6 7.9 25.0 0.76 7.6 17.4 1.1 1 0 0 1 1 1 0 Nop14-like family Cytomega_UL84 PF06284.6 ETO04016.1 - 0.65 8.3 9.2 0.07 11.5 2.3 1.8 1 1 1 2 2 2 0 Cytomegalovirus UL84 protein FAM60A PF15396.1 ETO04016.1 - 0.69 9.6 8.2 0.96 9.1 5.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A SAPS PF04499.10 ETO04016.1 - 0.71 8.4 14.2 0.95 8.0 9.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CENP-T PF15511.1 ETO04016.1 - 1 8.5 15.2 1.4 8.1 10.6 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Astro_capsid PF03115.9 ETO04016.1 - 1.1 7.3 8.6 1.2 7.3 6.0 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor VID27 PF08553.5 ETO04016.1 - 1.6 6.8 15.2 1.8 6.7 10.5 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Nop25 PF09805.4 ETO04016.1 - 1.7 8.7 19.0 2.8 8.0 13.1 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Tim54 PF11711.3 ETO04016.1 - 2.5 6.5 8.5 4.1 5.9 5.9 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NOA36 PF06524.7 ETO04016.1 - 2.8 7.1 23.0 4.9 6.3 16.0 1.4 1 0 0 1 1 1 0 NOA36 protein Afi1 PF07792.7 ETO04016.1 - 4.5 7.2 14.0 6.8 6.6 9.7 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Spore_coat_CotO PF14153.1 ETO04016.1 - 6.1 6.2 11.7 8.5 5.7 8.1 1.2 1 0 0 1 1 1 0 Spore coat protein CotO NPR3 PF03666.8 ETO04016.1 - 7.6 4.9 13.4 11 4.4 9.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Paramyxo_ncap PF00973.14 ETO04016.1 - 9 4.8 10.2 12 4.4 7.1 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein PC4 PF02229.11 ETO04019.1 - 4.3e-18 64.2 0.3 4.6e-17 60.9 0.0 2.3 2 1 0 2 2 2 1 Transcriptional Coactivator p15 (PC4) Mem_trans PF03547.13 ETO04019.1 - 0.02 13.2 1.2 0.02 13.2 0.8 1.1 1 0 0 1 1 1 0 Membrane transport protein PRP21_like_P PF12230.3 ETO04019.1 - 0.55 9.6 9.8 17 4.8 6.1 2.7 3 0 0 3 3 3 0 Pre-mRNA splicing factor PRP21 like protein Rpp20 PF12328.3 ETO04020.1 - 3.5 7.2 8.0 23 4.6 5.6 2.0 1 1 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P ABC_tran_2 PF12848.2 ETO04021.1 - 0.15 11.9 5.5 0.21 11.4 3.8 1.3 1 0 0 1 1 1 0 ABC transporter LETM1 PF07766.8 ETO04022.1 - 0.01 14.9 0.5 0.013 14.5 0.3 1.2 1 0 0 1 1 1 0 LETM1-like protein Pox_RNA_Pol_19 PF05320.7 ETO04022.1 - 0.14 11.9 3.5 0.23 11.1 2.4 1.4 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Apis_Csd PF11671.3 ETO04022.1 - 0.33 10.7 4.5 0.48 10.2 3.1 1.2 1 0 0 1 1 1 0 Complementary sex determiner protein Packaging_FI PF14000.1 ETO04022.1 - 0.61 10.2 5.2 0.94 9.6 3.6 1.4 1 1 0 1 1 1 0 DNA packaging protein FI Telomere_reg-2 PF10193.4 ETO04023.1 - 1.7e-19 70.1 0.1 2.3e-19 69.7 0.1 1.2 1 0 0 1 1 1 1 Telomere length regulation protein Receptor_2B4 PF11465.3 ETO04024.1 - 0.011 15.6 1.1 0.015 15.1 0.3 1.5 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 GAF_3 PF13492.1 ETO04025.1 - 1.5e-06 28.3 0.0 1.6e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 ETO04025.1 - 0.11 12.6 0.0 0.3 11.1 0.0 1.8 1 1 0 1 1 1 0 GAF domain GAF_2 PF13185.1 ETO04025.1 - 0.12 12.8 0.0 0.18 12.3 0.0 1.3 1 1 0 1 1 1 0 GAF domain Colipase-like PF15083.1 ETO04025.1 - 0.23 11.3 3.7 0.38 10.7 2.4 1.6 1 1 0 1 1 1 0 Colipase-like Vps39_1 PF10366.4 ETO04025.1 - 2.6 8.1 4.8 1.6 8.8 0.1 2.5 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 Epimerase PF01370.16 ETO04026.1 - 4.1e-18 65.6 0.0 4.4e-18 65.5 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ETO04026.1 - 0.0084 15.0 0.0 0.0084 15.0 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein DUF3336 PF11815.3 ETO04027.1 - 9.8e-11 41.3 0.1 1.3e-10 40.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) PA PF02225.17 ETO04028.1 - 6.6e-11 41.7 0.0 9.1e-11 41.3 0.0 1.2 1 0 0 1 1 1 1 PA domain RhoGEF PF00621.15 ETO04030.1 - 2.4e-22 79.6 1.4 3.2e-22 79.2 0.9 1.1 1 0 0 1 1 1 1 RhoGEF domain ABC_tran PF00005.22 ETO04031.1 - 4.6e-10 39.9 0.0 6e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 ETO04031.1 - 1.2e-05 25.4 0.0 1.3e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 ETO04031.1 - 0.034 13.3 0.0 0.04 13.1 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Pkinase PF00069.20 ETO04032.1 - 1.5e-12 47.2 0.3 4.2e-11 42.4 0.0 2.3 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO04032.1 - 0.0011 18.0 0.0 0.075 12.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase SR-25 PF10500.4 ETO04032.1 - 0.089 12.2 11.1 0.11 11.9 7.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CDC45 PF02724.9 ETO04032.1 - 0.12 10.3 5.3 0.14 10.1 3.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Pox_RNA_Pol_19 PF05320.7 ETO04032.1 - 0.37 10.5 3.6 0.51 10.0 2.5 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF4614 PF15391.1 ETO04032.1 - 0.62 9.8 7.5 0.71 9.6 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Apt1 PF10351.4 ETO04032.1 - 1.5 7.5 7.1 1.8 7.3 4.9 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain TPR_14 PF13428.1 ETO04033.1 - 1.1e-05 25.6 0.0 0.012 16.1 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO04033.1 - 7.1e-05 22.4 0.1 0.0089 15.8 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO04033.1 - 0.0022 17.8 0.1 0.0052 16.6 0.0 1.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO04033.1 - 0.0024 18.2 0.1 1.6 9.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETO04033.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETO04033.1 - 0.025 14.3 0.1 0.17 11.7 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETO04033.1 - 0.04 13.5 0.1 0.63 9.7 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETO04033.1 - 0.051 13.9 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4070 PF13282.1 ETO04033.1 - 0.067 12.7 0.0 0.2 11.1 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4070) TPR_11 PF13414.1 ETO04033.1 - 0.08 12.6 0.0 0.7 9.5 0.0 2.1 2 0 0 2 2 2 0 TPR repeat RPN7 PF10602.4 ETO04033.1 - 0.097 12.0 0.5 0.17 11.2 0.2 1.6 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_7 PF13176.1 ETO04033.1 - 0.11 12.3 0.2 0.76 9.7 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.20 ETO04035.1 - 2.2e-42 145.0 0.1 2.4e-42 144.8 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO04035.1 - 8.4e-23 80.7 0.0 9e-23 80.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO04035.1 - 7.6e-06 25.0 0.0 1.2e-05 24.4 0.0 1.2 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETO04035.1 - 7.7e-05 21.8 0.2 9.4e-05 21.5 0.2 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 ETO04035.1 - 0.0026 17.1 0.0 0.0032 16.8 0.0 1.1 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 ETO04035.1 - 0.073 11.8 0.0 0.073 11.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF1679 PF07914.6 ETO04035.1 - 0.095 11.3 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Cys_rich_KTR PF14205.1 ETO04037.1 - 0.0093 15.4 0.1 0.018 14.4 0.1 1.4 1 0 0 1 1 1 1 Cysteine-rich KTR SART-1 PF03343.8 ETO04038.1 - 0.0051 15.2 4.1 0.005 15.2 2.9 1.1 1 0 0 1 1 1 1 SART-1 family Pox_Ag35 PF03286.9 ETO04038.1 - 0.29 10.6 4.3 0.37 10.3 3.0 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NST1 PF13945.1 ETO04038.1 - 1.7 8.6 7.0 3.3 7.7 4.8 1.5 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF1754 PF08555.5 ETO04038.1 - 1.9 9.1 15.3 0.57 10.8 8.6 1.6 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) DUF1387 PF07139.6 ETO04038.1 - 8 5.9 10.7 11 5.5 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Pkinase PF00069.20 ETO04039.1 - 0.00012 21.2 0.0 0.00018 20.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Zn_ribbon_recom PF13408.1 ETO04039.1 - 0.074 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Recombinase PF07508.8 ETO04039.1 - 0.1 12.8 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Recombinase TAF4 PF05236.9 ETO04040.1 - 0.018 14.3 9.5 0.027 13.7 6.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Macoilin PF09726.4 ETO04040.1 - 0.022 13.0 1.1 0.02 13.2 0.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Peptidase_C1 PF00112.18 ETO04041.1 - 1.1e-32 113.6 2.3 1.3e-32 113.4 1.6 1.0 1 0 0 1 1 1 1 Papain family cysteine protease DUF2222 PF09984.4 ETO04041.1 - 0.088 12.2 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized signal transduction histidine kinase domain (DUF2222) CHAT PF12770.2 ETO04042.1 - 0.0038 16.3 0.1 0.0045 16.1 0.0 1.1 1 0 0 1 1 1 1 CHAT domain Col_cuticle_N PF01484.12 ETO04042.1 - 0.0047 16.5 0.0 0.0098 15.5 0.0 1.6 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain DUF2207 PF09972.4 ETO04042.1 - 0.011 14.3 0.2 0.013 14.1 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DoxX_3 PF13781.1 ETO04042.1 - 0.013 15.8 1.6 0.019 15.3 1.1 1.1 1 0 0 1 1 1 0 DoxX-like family MscS_TM PF12794.2 ETO04042.1 - 0.017 13.7 0.5 0.02 13.4 0.3 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Brr6_like_C_C PF10104.4 ETO04042.1 - 0.057 12.9 0.0 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain Gate PF07670.9 ETO04042.1 - 0.093 12.6 0.8 0.13 12.1 0.6 1.1 1 0 0 1 1 1 0 Nucleoside recognition SCIMP PF15050.1 ETO04042.1 - 0.1 12.4 0.1 0.34 10.8 0.0 1.8 1 1 1 2 2 2 0 SCIMP protein DUF3899 PF13038.1 ETO04042.1 - 1.3 9.1 5.0 8 6.6 0.4 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF3899) eIF2A PF08662.6 ETO04043.1 - 5.4e-07 29.5 0.0 9.9e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Spot_14 PF07084.7 ETO04044.1 - 0.07 13.0 1.4 0.094 12.5 1.0 1.2 1 0 0 1 1 1 0 Thyroid hormone-inducible hepatic protein Spot 14 Nucleo_P87 PF07267.6 ETO04044.1 - 0.69 8.5 7.5 0.73 8.4 5.2 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 VID27 PF08553.5 ETO04044.1 - 2.6 6.1 9.1 3.2 5.8 6.3 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein RR_TM4-6 PF06459.7 ETO04044.1 - 2.8 7.7 8.8 3.2 7.5 6.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.9 ETO04044.1 - 6.4 4.6 9.2 7 4.5 6.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Trypan_PARP PF05887.6 ETO04045.1 - 0.013 15.2 14.4 0.017 14.9 10.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SR-25 PF10500.4 ETO04045.1 - 0.024 14.0 22.5 0.031 13.7 15.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Daxx PF03344.10 ETO04045.1 - 0.27 9.6 25.5 0.3 9.5 17.7 1.0 1 0 0 1 1 1 0 Daxx Family TFIIA PF03153.8 ETO04045.1 - 0.48 10.2 26.0 0.55 10.0 18.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1510 PF07423.6 ETO04045.1 - 0.65 9.3 26.1 0.81 9.0 18.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FAM60A PF15396.1 ETO04045.1 - 0.69 9.6 12.5 0.84 9.3 8.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Dsh_C PF12316.3 ETO04045.1 - 0.85 9.6 11.6 1.1 9.3 8.0 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal BUD22 PF09073.5 ETO04045.1 - 1.2 8.1 36.3 1.4 7.8 25.1 1.1 1 0 0 1 1 1 0 BUD22 Myc_N PF01056.13 ETO04045.1 - 1.9 7.5 13.4 2.4 7.2 9.3 1.3 1 0 0 1 1 1 0 Myc amino-terminal region MIP-T3 PF10243.4 ETO04045.1 - 2.7 6.3 26.8 3.1 6.1 18.6 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CDC27 PF09507.5 ETO04045.1 - 2.9 7.0 28.3 3.2 6.8 19.6 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SAPS PF04499.10 ETO04045.1 - 3.1 6.3 13.8 3.4 6.2 9.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DDHD PF02862.12 ETO04045.1 - 3.1 7.5 10.9 4.4 7.0 7.5 1.3 1 0 0 1 1 1 0 DDHD domain Raftlin PF15250.1 ETO04045.1 - 8.2 4.8 10.6 10 4.4 7.3 1.3 1 0 0 1 1 1 0 Raftlin Macoilin PF09726.4 ETO04045.1 - 9.8 4.3 12.1 11 4.2 8.4 1.0 1 0 0 1 1 1 0 Transmembrane protein PBP1_TM PF14812.1 ETO04046.1 - 1.6 9.1 5.5 2.5 8.4 3.8 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Xpo1 PF08389.7 ETO04047.1 - 0.096 12.6 0.0 0.28 11.0 0.0 1.7 2 0 0 2 2 2 0 Exportin 1-like protein Cytochrome_C7 PF14522.1 ETO04049.1 - 0.066 12.8 0.3 0.08 12.5 0.2 1.2 1 0 0 1 1 1 0 Cytochrome c7 Ribosomal_S14 PF00253.16 ETO04049.1 - 0.089 12.1 3.4 0.15 11.4 2.4 1.4 1 0 0 1 1 1 0 Ribosomal protein S14p/S29e DUF678 PF05077.7 ETO04049.1 - 1.2 9.1 4.6 1.8 8.5 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF678) Pkinase PF00069.20 ETO04050.1 - 6.4e-31 107.4 0.1 7.4e-31 107.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO04050.1 - 4e-16 58.8 0.0 4.8e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 ETO04050.1 - 0.00049 19.0 0.2 0.00069 18.5 0.1 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.18 ETO04050.1 - 0.0086 15.8 0.0 0.025 14.3 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 ETO04050.1 - 0.019 14.0 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 ETO04050.1 - 0.033 13.5 0.2 0.053 12.8 0.1 1.3 1 0 0 1 1 1 0 RIO1 family ERK-JNK_inhib PF15002.1 ETO04050.1 - 0.081 12.2 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor DUF3415 PF11895.3 ETO04051.1 - 0.071 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3415) WD40 PF00400.27 ETO04053.1 - 0.00019 21.1 0.0 0.00032 20.4 0.0 1.4 1 0 0 1 1 1 1 WD domain, G-beta repeat PV_NSP1 PF12433.3 ETO04054.1 - 0.0038 17.2 1.9 0.0057 16.6 1.3 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein 1 DUF4196 PF13846.1 ETO04054.1 - 0.032 14.5 0.9 0.049 13.9 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4196) TFIIE_alpha PF02002.12 ETO04054.1 - 1.1 8.7 5.0 0.54 9.7 2.0 1.5 1 1 1 2 2 2 0 TFIIE alpha subunit Phytoreo_S7 PF07236.6 ETO04055.1 - 0.27 9.5 8.1 0.37 9.0 5.6 1.1 1 0 0 1 1 1 0 Phytoreovirus S7 protein DUF4279 PF14106.1 ETO04055.1 - 0.28 11.0 3.1 0.19 11.6 0.8 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4279) BPL_N PF09825.4 ETO04055.1 - 0.66 8.7 13.1 0.83 8.3 9.1 1.0 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal PRTase_1 PF11202.3 ETO04055.1 - 1 8.2 8.5 0.35 9.8 3.5 1.8 1 1 1 2 2 2 0 Phosphoribosyl transferase (PRTase) Atg14 PF10186.4 ETO04055.1 - 3.2 6.6 23.3 0.63 8.9 13.7 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF641 PF04859.7 ETO04055.1 - 8.8 6.0 22.0 0.4 10.4 2.7 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Pkinase PF00069.20 ETO04056.1 - 5.3e-38 130.6 0.0 6.8e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO04056.1 - 2.2e-16 59.6 0.0 2.7e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETO04056.1 - 0.0049 16.6 0.0 0.035 13.8 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 ETO04056.1 - 0.043 12.6 0.0 0.043 12.6 0.0 1.8 2 0 0 2 2 2 0 Seadornavirus VP7 Kdo PF06293.9 ETO04056.1 - 0.099 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2722 PF10846.3 ETO04057.1 - 0.091 11.7 9.7 0.096 11.6 6.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Rota_NS26 PF01525.11 ETO04057.1 - 0.16 11.7 6.5 0.19 11.4 4.5 1.1 1 0 0 1 1 1 0 Rotavirus NS26 FLO_LFY PF01698.11 ETO04057.1 - 2.3 6.9 5.9 2.7 6.7 4.1 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Receptor_IA-2 PF11548.3 ETO04058.1 - 0.1 12.5 0.6 0.18 11.7 0.4 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase receptor IA-2 DUF2115 PF09888.4 ETO04058.1 - 0.19 11.7 4.1 0.36 10.9 2.9 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) Ank PF00023.25 ETO04059.1 - 8.5e-12 44.2 0.6 5.4e-07 29.1 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 ETO04059.1 - 2e-10 40.9 0.3 5.6e-10 39.4 0.1 1.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO04059.1 - 4.4e-10 39.7 0.1 5.9e-10 39.3 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO04059.1 - 9.4e-10 37.7 0.6 0.00013 21.8 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 ETO04059.1 - 5.7e-07 29.5 0.4 0.00014 21.9 0.1 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) PT PF04886.7 ETO04060.1 - 2.9e-06 26.4 14.6 1.7e-05 24.0 1.8 2.3 1 1 1 2 2 2 2 PT repeat UBA PF00627.26 ETO04061.1 - 0.00013 21.6 0.2 0.00027 20.6 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain MIP-T3 PF10243.4 ETO04064.1 - 0.0052 15.3 31.1 0.0056 15.2 21.5 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 BEN PF10523.4 ETO04064.1 - 0.012 15.6 1.1 0.024 14.6 0.8 1.5 1 0 0 1 1 1 0 BEN domain DUF572 PF04502.8 ETO04064.1 - 0.044 12.9 24.7 0.057 12.6 17.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) CENP-N PF05238.8 ETO04064.1 - 0.065 12.2 16.4 0.087 11.8 11.4 1.3 1 0 0 1 1 1 0 Kinetochore protein CHL4 like DUF2146 PF10220.4 ETO04064.1 - 0.11 10.5 13.9 0.13 10.2 9.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) U79_P34 PF03064.11 ETO04064.1 - 7 6.0 34.0 2.2 7.7 21.8 1.5 2 0 0 2 2 2 0 HSV U79 / HCMV P34 SDA1 PF05285.7 ETO04065.1 - 0.057 12.6 17.5 0.07 12.3 12.1 1.2 1 0 0 1 1 1 0 SDA1 CybS PF05328.7 ETO04065.1 - 0.12 11.9 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 CybS Daxx PF03344.10 ETO04065.1 - 0.16 10.4 12.0 0.18 10.2 8.3 1.2 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 ETO04065.1 - 0.41 8.4 18.8 0.48 8.2 13.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 ETO04065.1 - 0.8 7.6 14.4 1 7.3 10.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.12 ETO04065.1 - 1.8 8.3 10.5 2 8.1 5.1 2.0 2 0 0 2 2 2 0 DDHD domain RP-C_C PF11800.3 ETO04065.1 - 4.7 6.8 8.9 2.9 7.5 3.5 1.9 2 0 0 2 2 2 0 Replication protein C C-terminal region CDC27 PF09507.5 ETO04066.1 - 0.35 10.0 38.3 0.42 9.7 26.5 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MIP-T3 PF10243.4 ETO04066.1 - 3.7 5.8 44.2 4.8 5.5 30.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Asp-B-Hydro_N PF05279.6 ETO04066.1 - 8.6 6.1 35.8 11 5.7 24.8 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Mucin PF01456.12 ETO04067.1 - 0.0053 16.5 8.6 0.0071 16.1 6.0 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein CAP PF00188.21 ETO04068.1 - 0.18 12.3 1.2 0.33 11.4 0.8 1.7 1 1 0 1 1 1 0 Cysteine-rich secretory protein family Pex14_N PF04695.8 ETO04068.1 - 8.6 6.4 7.9 9.6 6.2 2.1 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1103 PF06513.6 ETO04069.1 - 0.029 13.7 0.7 0.034 13.5 0.5 1.1 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) EF-hand_6 PF13405.1 ETO04070.1 - 0.036 13.9 0.0 0.15 12.0 0.0 2.1 1 1 0 1 1 1 0 EF-hand domain PA PF02225.17 ETO04071.1 - 1.6e-14 53.3 0.0 2.2e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 PA domain IncA PF04156.9 ETO04072.1 - 0.00092 18.8 5.0 0.0011 18.6 3.5 1.1 1 0 0 1 1 1 1 IncA protein Filament PF00038.16 ETO04072.1 - 0.0029 17.1 1.8 0.0033 16.9 1.2 1.1 1 0 0 1 1 1 1 Intermediate filament protein CENP-F_leu_zip PF10473.4 ETO04072.1 - 0.0035 17.2 4.7 0.0044 16.8 3.2 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GOLGA2L5 PF15070.1 ETO04072.1 - 0.0056 15.2 0.3 0.007 14.9 0.2 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 ATG16 PF08614.6 ETO04072.1 - 0.0083 15.9 3.8 0.011 15.5 2.6 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) WEMBL PF05701.6 ETO04072.1 - 0.0098 14.3 0.6 0.012 14.0 0.4 1.0 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Myosin_tail_1 PF01576.14 ETO04072.1 - 0.012 13.3 2.5 0.014 13.2 1.7 1.0 1 0 0 1 1 1 0 Myosin tail DUF972 PF06156.8 ETO04072.1 - 0.016 15.5 4.1 0.023 15.0 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) GAS PF13851.1 ETO04072.1 - 0.016 14.4 4.0 0.021 14.0 2.7 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 ETO04072.1 - 0.017 14.1 5.9 0.02 13.9 4.1 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 RTBV_P46 PF06216.6 ETO04072.1 - 0.042 12.7 0.6 0.05 12.4 0.4 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein DivIVA PF05103.8 ETO04072.1 - 0.045 13.8 2.3 0.067 13.2 1.6 1.3 1 0 0 1 1 1 0 DivIVA protein Sec34 PF04136.10 ETO04072.1 - 0.05 13.2 1.8 0.062 13.0 1.3 1.1 1 0 0 1 1 1 0 Sec34-like family Nup54 PF13874.1 ETO04072.1 - 0.057 13.0 3.1 0.074 12.7 2.2 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 TBPIP PF07106.8 ETO04072.1 - 0.077 12.5 5.5 0.097 12.2 3.8 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF648 PF04890.8 ETO04072.1 - 0.081 12.0 2.1 0.088 11.9 1.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF648) Kinetocho_Slk19 PF12709.2 ETO04072.1 - 0.085 12.9 3.6 0.076 13.0 1.4 1.6 1 1 1 2 2 2 0 Central kinetochore-associated bZIP_2 PF07716.10 ETO04072.1 - 0.13 12.0 3.7 0.14 11.9 0.9 2.1 1 1 1 2 2 2 0 Basic region leucine zipper ADIP PF11559.3 ETO04072.1 - 0.18 11.7 6.5 0.22 11.4 4.5 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding HemX PF04375.9 ETO04072.1 - 0.19 10.2 4.0 0.25 9.9 2.7 1.1 1 0 0 1 1 1 0 HemX FlaC_arch PF05377.6 ETO04072.1 - 0.29 11.0 1.5 7.5 6.5 0.2 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Enkurin PF13864.1 ETO04072.1 - 0.47 10.7 4.0 0.61 10.3 2.7 1.2 1 0 0 1 1 1 0 Calmodulin-binding Pterin_bind PF00809.17 ETO04073.1 - 6.7e-43 146.5 0.3 7.7e-43 146.3 0.2 1.0 1 0 0 1 1 1 1 Pterin binding enzyme CdhD PF03599.11 ETO04073.1 - 0.0033 15.9 0.0 0.0052 15.3 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit ComA PF02679.10 ETO04073.1 - 0.0055 15.7 0.1 0.27 10.1 0.0 2.1 2 0 0 2 2 2 2 (2R)-phospho-3-sulfolactate synthase (ComA) MtrH PF02007.13 ETO04073.1 - 0.033 13.1 0.1 0.035 13.0 0.0 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase MtrH subunit MBT PF02820.13 ETO04074.1 - 0.00024 20.9 0.1 0.00042 20.1 0.0 1.3 1 0 0 1 1 1 1 mbt repeat Tudor-knot PF11717.3 ETO04074.1 - 0.24 11.1 3.6 0.43 10.3 2.5 1.7 1 1 0 1 1 1 0 RNA binding activity-knot of a chromodomain WD40 PF00400.27 ETO04075.1 - 2.1e-11 43.2 0.0 8.9e-07 28.5 0.1 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Gmad1 PF10647.4 ETO04075.1 - 0.0043 16.4 0.1 0.036 13.4 0.0 2.0 2 0 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain PD40 PF07676.7 ETO04075.1 - 0.036 13.7 0.1 0.5 10.0 0.1 2.2 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Aminotran_4 PF01063.14 ETO04075.1 - 0.04 13.3 0.0 0.058 12.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class IV Cupin_8 PF13621.1 ETO04076.1 - 1.1e-11 44.7 0.4 2.2e-11 43.7 0.3 1.4 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 ETO04076.1 - 0.00016 21.0 0.1 0.00026 20.3 0.1 1.4 1 1 0 1 1 1 1 Cupin superfamily protein Sulfotransfer_3 PF13469.1 ETO04077.1 - 0.00013 22.9 0.0 0.00017 22.5 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 ETO04077.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Sulfotransferase domain WD40 PF00400.27 ETO04079.1 - 0.0008 19.2 0.1 0.87 9.5 0.1 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat AAA PF00004.24 ETO04080.1 - 0.015 15.4 0.3 0.062 13.4 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IU_nuc_hydro PF01156.14 ETO04081.1 - 3.2e-33 115.2 0.0 3.9e-33 114.9 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Anoctamin PF04547.7 ETO04082.1 - 2.7e-32 112.0 2.5 2.8e-32 111.9 1.7 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Cortexin PF11057.3 ETO04082.1 - 0.011 15.3 0.5 0.016 14.7 0.3 1.4 1 1 0 1 1 1 0 Cortexin of kidney Per1 PF04080.8 ETO04082.1 - 0.011 15.1 2.3 0.013 14.9 1.6 1.1 1 0 0 1 1 1 0 Per1-like DUF805 PF05656.9 ETO04082.1 - 0.077 12.8 3.4 0.78 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF805) DUF2254 PF10011.4 ETO04082.1 - 0.26 9.6 4.5 0.39 9.1 3.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) YecM PF06185.7 ETO04083.1 - 0.042 13.0 0.1 0.058 12.5 0.1 1.3 1 0 0 1 1 1 0 YecM protein DUF1387 PF07139.6 ETO04083.1 - 0.05 13.2 11.2 0.054 13.1 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Pox_Ag35 PF03286.9 ETO04083.1 - 0.05 13.1 12.5 0.053 13.0 8.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein XAP5 PF04921.9 ETO04083.1 - 0.052 13.1 13.0 0.064 12.8 9.0 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator DUF1754 PF08555.5 ETO04083.1 - 0.19 12.3 22.9 0.3 11.7 15.9 1.3 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) SpoIIIAH PF12685.2 ETO04083.1 - 0.19 11.1 10.3 0.24 10.8 7.1 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein FAM60A PF15396.1 ETO04083.1 - 0.4 10.4 9.3 0.5 10.0 6.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Macoilin PF09726.4 ETO04083.1 - 0.59 8.3 11.5 0.62 8.2 8.0 1.0 1 0 0 1 1 1 0 Transmembrane protein NARP1 PF12569.3 ETO04083.1 - 1.8 7.1 14.0 1.8 7.2 9.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RNA_pol_Rpb1_5 PF04998.12 ETO04083.1 - 4 6.6 8.0 4.3 6.5 5.6 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Rtf2 PF04641.7 ETO04083.1 - 4 6.5 15.1 5.3 6.1 10.4 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Gti1_Pac2 PF09729.4 ETO04083.1 - 5.1 6.9 7.6 7 6.4 5.3 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family DUF2457 PF10446.4 ETO04083.1 - 9.6 4.8 14.7 12 4.4 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DiS_P_DiS PF06750.8 ETO04084.1 - 0.16 11.7 0.6 0.21 11.4 0.2 1.4 1 1 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain G-alpha PF00503.15 ETO04085.1 - 1e-05 24.4 0.0 1.2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Pox_P4B PF03292.9 ETO04085.1 - 0.012 13.5 0.0 0.013 13.4 0.0 1.0 1 0 0 1 1 1 0 Poxvirus P4B major core protein Mur_ligase_M PF08245.7 ETO04085.1 - 0.013 15.5 0.1 0.017 15.1 0.1 1.2 1 0 0 1 1 1 0 Mur ligase middle domain TSP9 PF11493.3 ETO04085.1 - 0.081 13.4 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 Fucose_iso_N2 PF07882.7 ETO04086.1 - 0.01 15.4 1.7 0.013 15.1 1.2 1.1 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain Cgr1 PF03879.9 ETO04086.1 - 0.017 15.2 12.1 0.023 14.8 8.0 1.6 1 1 1 2 2 2 0 Cgr1 family DUF2992 PF11208.3 ETO04086.1 - 0.039 13.8 7.5 0.048 13.5 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) DUF4254 PF14063.1 ETO04086.1 - 0.039 13.5 2.8 0.042 13.4 1.0 1.6 1 1 0 2 2 2 0 Protein of unknown function (DUF4254) LcrG PF07216.7 ETO04086.1 - 0.056 13.4 0.6 0.085 12.8 0.4 1.3 1 0 0 1 1 1 0 LcrG protein DDE_Tnp_IS66 PF03050.9 ETO04086.1 - 0.07 12.3 1.2 0.08 12.1 0.8 1.1 1 0 0 1 1 1 0 Transposase IS66 family DUF1849 PF08904.6 ETO04086.1 - 0.082 12.2 1.1 0.095 12.0 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1849) Peptidase_C6 PF00851.13 ETO04086.1 - 0.093 11.3 1.4 0.098 11.2 1.0 1.0 1 0 0 1 1 1 0 Helper component proteinase Colicin-DNase PF12639.2 ETO04086.1 - 0.19 11.9 5.6 0.6 10.3 1.6 2.1 1 1 1 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin Ribosomal_L37 PF08561.5 ETO04086.1 - 4 7.0 6.7 1 9.0 1.2 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L37 FimP PF09766.4 ETO04087.1 - 0.044 12.8 9.1 0.05 12.6 6.3 1.1 1 0 0 1 1 1 0 Fms-interacting protein Tim54 PF11711.3 ETO04087.1 - 0.24 9.9 3.7 0.29 9.7 2.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Atrophin-1 PF03154.10 ETO04087.1 - 3 5.8 6.6 3.8 5.5 4.6 1.0 1 0 0 1 1 1 0 Atrophin-1 family RP-C_C PF11800.3 ETO04087.1 - 4.2 7.0 9.0 6.1 6.4 6.2 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region EpsG PF14897.1 ETO04088.1 - 0.00045 19.2 4.8 0.0068 15.3 2.1 2.1 2 0 0 2 2 2 2 EpsG family Oxidored_q3 PF00499.15 ETO04088.1 - 0.55 10.0 8.6 1 9.1 1.1 2.4 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 AAA PF00004.24 ETO04089.1 - 7.7e-37 126.4 0.0 2.6e-36 124.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 ETO04089.1 - 3e-09 36.6 0.0 1.2e-08 34.7 0.0 2.1 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 ETO04089.1 - 1.1e-05 25.6 0.0 0.00011 22.3 0.0 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 ETO04089.1 - 3.1e-05 23.1 0.0 6.1e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 ETO04089.1 - 9.6e-05 22.3 0.0 0.00062 19.7 0.0 2.4 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 ETO04089.1 - 0.00022 21.1 0.0 0.00085 19.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 ETO04089.1 - 0.00031 20.4 0.1 0.01 15.5 0.1 2.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 ETO04089.1 - 0.00043 19.4 0.6 0.0025 16.9 0.1 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 ETO04089.1 - 0.0009 20.0 0.0 0.0034 18.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETO04089.1 - 0.001 19.4 0.0 0.0048 17.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 ETO04089.1 - 0.0016 17.8 0.0 0.0032 16.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein NB-ARC PF00931.17 ETO04089.1 - 0.0034 16.2 0.4 0.027 13.3 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_28 PF13521.1 ETO04089.1 - 0.0062 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 ETO04089.1 - 0.0083 15.5 0.0 0.066 12.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 ETO04089.1 - 0.009 15.9 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETO04089.1 - 0.011 15.5 0.1 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain KaiC PF06745.8 ETO04089.1 - 0.012 14.7 1.1 0.37 9.8 0.0 2.7 2 1 1 3 3 3 0 KaiC AAA_24 PF13479.1 ETO04089.1 - 0.013 15.1 1.8 0.037 13.6 0.0 2.5 2 1 0 2 2 2 0 AAA domain NACHT PF05729.7 ETO04089.1 - 0.013 15.1 0.0 0.28 10.8 0.0 2.4 2 0 0 2 2 2 0 NACHT domain DUF4502 PF14950.1 ETO04089.1 - 0.013 14.6 2.5 0.021 14.0 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4502) Sigma54_activ_2 PF14532.1 ETO04089.1 - 0.018 15.1 0.0 0.074 13.1 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.1 ETO04089.1 - 0.023 14.6 0.0 0.11 12.4 0.0 1.9 1 1 0 2 2 2 0 AAA ATPase domain DUF1374 PF07118.6 ETO04089.1 - 0.024 14.7 1.0 0.076 13.1 0.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1374) RNA_helicase PF00910.17 ETO04089.1 - 0.032 14.4 0.9 0.29 11.3 0.0 3.0 3 1 0 3 3 2 0 RNA helicase Arch_ATPase PF01637.13 ETO04089.1 - 0.05 13.3 2.8 0.12 12.0 0.0 2.9 2 2 0 2 2 2 0 Archaeal ATPase Sigma54_activat PF00158.21 ETO04089.1 - 0.051 13.0 0.0 0.25 10.7 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain MCP_N PF05581.7 ETO04089.1 - 0.088 12.9 0.7 0.54 10.4 0.0 2.4 2 0 0 2 2 2 0 Vibrio chemotaxis protein N terminus DnaI_N PF07319.6 ETO04089.1 - 0.29 11.3 3.6 0.39 10.9 0.2 2.7 2 0 0 2 2 2 0 Primosomal protein DnaI N-terminus Seipin PF06775.9 ETO04090.1 - 1.3e-05 24.7 0.0 1.6e-05 24.4 0.0 1.0 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Trypan_PARP PF05887.6 ETO04090.1 - 0.017 14.9 0.2 0.023 14.5 0.1 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Apis_Csd PF11671.3 ETO04091.1 - 0.0062 16.3 2.2 0.0087 15.8 1.5 1.2 1 0 0 1 1 1 1 Complementary sex determiner protein HEAT_2 PF13646.1 ETO04092.1 - 1.4e-17 63.7 0.0 1e-15 57.7 0.0 2.1 1 1 1 2 2 2 2 HEAT repeats HEAT_PBS PF03130.11 ETO04092.1 - 2.4e-08 33.6 0.0 0.00089 19.5 0.0 3.4 4 0 0 4 4 4 2 PBS lyase HEAT-like repeat HEAT PF02985.17 ETO04092.1 - 0.00048 19.9 0.0 0.021 14.8 0.0 3.1 3 0 0 3 3 3 1 HEAT repeat DUF1546 PF07571.8 ETO04092.1 - 0.0016 18.5 0.0 0.52 10.4 0.0 2.3 1 1 0 2 2 2 2 Protein of unknown function (DUF1546) HEAT_EZ PF13513.1 ETO04092.1 - 0.003 17.9 0.0 0.036 14.5 0.0 2.5 1 1 2 3 3 3 1 HEAT-like repeat Arm PF00514.18 ETO04092.1 - 0.17 11.7 0.2 0.38 10.6 0.0 1.7 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat DUF3492 PF11997.3 ETO04093.1 - 0.017 14.6 4.9 0.021 14.3 3.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) SseC PF04888.7 ETO04093.1 - 0.024 13.9 1.7 0.025 13.9 1.1 1.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family UPF0118 PF01594.11 ETO04093.1 - 0.044 12.7 0.2 0.05 12.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF20 ASL_C PF08328.6 ETO04093.1 - 0.05 13.4 4.5 0.068 13.0 3.1 1.2 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal IFT57 PF10498.4 ETO04093.1 - 0.051 12.3 9.2 0.053 12.2 6.4 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 RFPL3_antisense PF10489.4 ETO04093.1 - 0.065 13.0 1.1 0.12 12.1 0.7 1.5 1 1 0 1 1 1 0 Ret finger protein-like 3 antisense DUF2130 PF09903.4 ETO04093.1 - 0.068 11.9 12.3 0.2 10.3 8.5 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) Pex26 PF07163.7 ETO04093.1 - 0.086 11.7 0.4 0.094 11.6 0.3 1.0 1 0 0 1 1 1 0 Pex26 protein TMPIT PF07851.8 ETO04093.1 - 0.11 11.5 7.9 0.14 11.2 5.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein Caps_synth_GfcC PF06251.6 ETO04093.1 - 0.13 11.3 4.1 0.18 10.9 2.9 1.1 1 0 0 1 1 1 0 Capsule biosynthesis GfcC Serinc PF03348.10 ETO04093.1 - 0.19 10.4 4.7 0.23 10.1 3.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Mem_trans PF03547.13 ETO04093.1 - 0.24 9.6 1.4 0.29 9.3 1.0 1.0 1 0 0 1 1 1 0 Membrane transport protein CEP19 PF14933.1 ETO04093.1 - 0.25 11.6 7.2 0.29 11.4 5.0 1.1 1 0 0 1 1 1 0 CEP19-like protein HemX PF04375.9 ETO04093.1 - 0.31 9.6 6.2 0.35 9.4 4.3 1.0 1 0 0 1 1 1 0 HemX TEX13 PF15186.1 ETO04093.1 - 0.32 10.5 7.4 0.44 10.1 5.2 1.2 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Folate_carrier PF01770.13 ETO04093.1 - 0.33 9.4 2.1 0.38 9.2 1.5 1.1 1 0 0 1 1 1 0 Reduced folate carrier Atg14 PF10186.4 ETO04093.1 - 0.37 9.6 7.7 0.44 9.4 5.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Phage_GPO PF05929.6 ETO04093.1 - 0.48 9.6 7.3 0.59 9.3 5.1 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Sporozoite_P67 PF05642.6 ETO04093.1 - 0.48 8.2 3.1 0.26 9.0 1.0 1.3 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Seryl_tRNA_N PF02403.17 ETO04093.1 - 0.53 10.3 12.3 0.81 9.7 8.5 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain LOH1CR12 PF10158.4 ETO04093.1 - 0.69 9.7 7.3 1.4 8.7 5.1 1.5 1 1 0 1 1 1 0 Tumour suppressor protein Jnk-SapK_ap_N PF09744.4 ETO04093.1 - 0.93 9.4 12.9 1.4 8.9 8.9 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Tmemb_cc2 PF10267.4 ETO04093.1 - 0.98 7.9 12.6 1.3 7.5 8.7 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein TMF_DNA_bd PF12329.3 ETO04093.1 - 1.1 9.1 17.2 1.7 8.4 11.9 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Mgr1 PF08602.5 ETO04093.1 - 1.1 8.2 5.1 1.1 8.1 3.5 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit DUF3677 PF12432.3 ETO04093.1 - 1.2 9.6 6.1 2.7 8.4 4.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3677) IncA PF04156.9 ETO04093.1 - 1.3 8.5 9.9 1.7 8.2 6.9 1.1 1 0 0 1 1 1 0 IncA protein UBA_e1_C PF09358.5 ETO04093.1 - 2.3 8.3 7.1 1.6 8.9 3.7 1.6 1 1 1 2 2 2 0 Ubiquitin-activating enzyme e1 C-terminal domain Hydrolase_3 PF08282.7 ETO04093.1 - 3.6 7.0 9.0 4 6.9 6.2 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PEX11 PF05648.9 ETO04093.1 - 3.9 6.6 6.9 7.2 5.8 4.7 1.4 1 1 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) FlxA PF14282.1 ETO04093.1 - 4.7 7.2 18.2 3 7.8 6.8 2.2 1 1 1 2 2 2 0 FlxA-like protein AHH PF14412.1 ETO04093.1 - 5.7 6.9 8.5 17 5.4 5.8 1.7 1 1 1 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH DUF904 PF06005.7 ETO04093.1 - 6.2 7.1 16.9 23 5.3 11.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF904) ACCA PF03255.9 ETO04093.1 - 6.3 6.3 11.9 9.5 5.7 2.3 1.9 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF4446 PF14584.1 ETO04093.1 - 7.5 6.3 8.7 22 4.8 6.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) DUF4407 PF14362.1 ETO04093.1 - 9 5.1 10.4 13 4.6 7.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF948 PF06103.6 ETO04093.1 - 9.9 6.0 7.8 14 5.5 4.2 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) PAP_central PF04928.12 ETO04094.1 - 4.1e-09 35.6 0.0 6.5e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain Sigma70_ner PF04546.8 ETO04095.1 - 0.056 13.0 4.4 0.066 12.8 3.1 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region RasGAP PF00616.14 ETO04095.1 - 0.063 12.9 1.9 0.078 12.6 1.3 1.1 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase FAM176 PF14851.1 ETO04095.1 - 0.13 11.9 1.6 0.2 11.3 1.1 1.2 1 0 0 1 1 1 0 FAM176 family DUF755 PF05501.6 ETO04095.1 - 0.34 10.9 7.9 0.42 10.6 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF755) OAD_gamma PF04277.8 ETO04095.1 - 0.6 10.5 3.4 0.86 10.0 2.4 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain AATF-Che1 PF13339.1 ETO04095.1 - 5.4 7.1 11.7 0.99 9.5 0.8 2.1 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor IncA PF04156.9 ETO04095.1 - 7 6.1 10.1 9.5 5.7 7.0 1.1 1 0 0 1 1 1 0 IncA protein ANAPC15 PF15243.1 ETO04096.1 - 0.066 13.2 0.7 0.098 12.7 0.5 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 TAFII55_N PF04658.8 ETO04098.1 - 0.68 9.4 8.5 0.97 8.9 5.9 1.3 1 0 0 1 1 1 0 TAFII55 protein conserved region Peptidase_C37 PF05416.7 ETO04098.1 - 1.7 6.8 6.4 2.1 6.5 4.5 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase PPTA PF01239.17 ETO04099.1 - 0.065 12.6 0.1 0.19 11.1 0.1 1.9 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat p31comet PF06581.7 ETO04099.1 - 0.4 9.5 5.0 0.38 9.5 1.3 2.2 1 1 0 2 2 2 0 Mad1 and Cdc20-bound-Mad2 binding PAE PF03283.8 ETO04100.1 - 0.019 13.6 0.1 0.026 13.1 0.0 1.3 1 0 0 1 1 1 0 Pectinacetylesterase Chordopox_A13L PF05961.6 ETO04100.1 - 0.039 13.8 1.2 3.9 7.4 0.2 2.2 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Endonuc-dimeris PF09124.5 ETO04100.1 - 0.057 13.0 3.1 8.1 6.1 0.0 2.6 2 0 0 2 2 2 0 T4 recombination endonuclease VII, dimerisation ACCA PF03255.9 ETO04101.1 - 0.053 13.0 0.9 0.087 12.3 0.6 1.4 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF106 PF01956.11 ETO04101.1 - 0.057 12.9 0.0 0.27 10.7 0.0 1.9 1 1 0 1 1 1 0 Integral membrane protein DUF106 Spc7 PF08317.6 ETO04101.1 - 0.068 11.8 6.7 0.077 11.6 4.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein HALZ PF02183.13 ETO04101.1 - 0.091 12.4 2.6 0.96 9.2 1.8 2.2 1 1 0 1 1 1 0 Homeobox associated leucine zipper HD-ZIP_N PF04618.7 ETO04101.1 - 0.15 12.5 2.0 0.21 12.1 1.4 1.3 1 0 0 1 1 1 0 HD-ZIP protein N terminus WD40_alt PF14077.1 ETO04101.1 - 0.23 11.1 2.1 0.46 10.1 1.5 1.4 1 0 0 1 1 1 0 Alternative WD40 repeat motif DUF972 PF06156.8 ETO04101.1 - 0.34 11.2 8.2 0.41 11.0 5.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF3573 PF12097.3 ETO04101.1 - 0.39 9.2 3.7 0.45 9.0 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Paramyxo_ncap PF00973.14 ETO04101.1 - 0.42 9.2 6.8 0.51 8.9 4.7 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein L_lactis_ph-MCP PF06673.6 ETO04101.1 - 0.81 8.3 4.6 1 8.0 3.2 1.1 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein Herpes_UL25 PF01499.11 ETO04101.1 - 1 7.5 5.5 1.1 7.4 3.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family DivIC PF04977.10 ETO04101.1 - 1.6 8.2 6.1 4.3 6.9 4.2 1.9 1 1 0 1 1 1 0 Septum formation initiator TMF_DNA_bd PF12329.3 ETO04101.1 - 2.2 8.1 13.7 3.1 7.6 8.6 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 ETO04101.1 - 2.3 7.1 10.0 3 6.8 6.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 RP-C_C PF11800.3 ETO04101.1 - 2.6 7.6 6.9 3.9 7.1 4.8 1.4 1 1 0 1 1 1 0 Replication protein C C-terminal region Rabaptin PF03528.10 ETO04101.1 - 5.4 6.9 12.6 27 4.7 4.5 2.3 1 1 1 2 2 2 0 Rabaptin Cation_ATPase_C PF00689.16 ETO04103.1 - 0.026 14.0 3.6 0.038 13.5 2.5 1.1 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus P4Ha_N PF08336.6 ETO04103.1 - 0.039 13.7 0.6 0.056 13.2 0.4 1.2 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region UPF0561 PF10573.4 ETO04103.1 - 0.046 13.5 1.8 0.06 13.2 1.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 Pox_P21 PF05313.7 ETO04103.1 - 0.055 12.7 1.5 0.085 12.1 0.6 1.6 1 1 0 1 1 1 0 Poxvirus P21 membrane protein Oxysterol_BP PF01237.13 ETO04103.1 - 1.6 7.1 4.6 2.2 6.6 3.2 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein Kelch_1 PF01344.20 ETO04104.1 - 5.9e-11 41.7 0.1 7.6e-06 25.3 0.0 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.1 ETO04104.1 - 1.2e-06 28.4 0.1 0.00074 19.5 0.0 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.1 ETO04104.1 - 7.1e-06 25.8 0.1 0.023 14.6 0.0 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.10 ETO04104.1 - 6.6e-05 22.5 0.3 0.0087 15.8 0.0 2.6 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.1 ETO04104.1 - 0.00034 20.3 0.1 0.29 10.9 0.0 2.4 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO04104.1 - 0.00097 19.2 0.0 0.33 11.1 0.0 2.3 2 0 0 2 2 2 2 Galactose oxidase, central domain Acatn PF13000.2 ETO04104.1 - 0.096 11.1 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Acetyl-coenzyme A transporter 1 SART-1 PF03343.8 ETO04105.1 - 0.36 9.1 11.0 0.46 8.7 7.6 1.2 1 0 0 1 1 1 0 SART-1 family UPF0561 PF10573.4 ETO04105.1 - 0.99 9.2 7.3 4.6 7.0 0.4 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 DUF1754 PF08555.5 ETO04105.1 - 4.3 7.9 22.4 0.79 10.3 5.9 2.1 1 1 1 2 2 2 0 Eukaryotic family of unknown function (DUF1754) PINIT PF14324.1 ETO04106.1 - 0.045 13.8 0.6 0.066 13.2 0.4 1.4 1 1 0 1 1 1 0 PINIT domain Sigma_1s PF02454.11 ETO04106.1 - 0.068 12.9 1.0 0.089 12.5 0.7 1.2 1 0 0 1 1 1 0 Sigma 1s protein DUF1743 PF08489.6 ETO04106.1 - 0.072 12.8 0.3 0.087 12.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1743) DUF4252 PF14060.1 ETO04106.1 - 0.5 9.9 3.0 0.61 9.6 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) DUF3930 PF13067.1 ETO04109.1 - 0.057 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3930) Phage_Nu1 PF07471.7 ETO04110.1 - 0.0074 15.7 0.6 0.011 15.2 0.4 1.2 1 0 0 1 1 1 1 Phage DNA packaging protein Nu1 Plasmodium_Vir PF05795.6 ETO04110.1 - 1.9 7.6 16.1 2.6 7.1 11.2 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein YajC PF02699.10 ETO04111.1 - 0.076 12.6 0.2 0.076 12.6 0.1 2.8 3 0 0 3 3 3 0 Preprotein translocase subunit DUF3799 PF12684.2 ETO04113.1 - 0.015 14.6 1.1 3.3 7.0 0.1 2.0 1 1 1 2 2 2 0 PDDEXK-like domain of unknown function (DUF3799) Peptidase_C47 PF05543.8 ETO04113.1 - 0.1 12.0 0.4 0.13 11.6 0.3 1.2 1 0 0 1 1 1 0 Staphopain peptidase C47 WXG100 PF06013.7 ETO04113.1 - 0.24 11.4 1.5 6.9 6.7 0.3 2.2 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Red1 PF07964.6 ETO04115.1 - 3.9 5.5 13.5 4.5 5.3 9.4 1.0 1 0 0 1 1 1 0 Rec10 / Red1 SH2 PF00017.19 ETO04116.1 - 2.4e-07 30.4 0.0 8.3e-07 28.7 0.0 1.8 1 1 0 1 1 1 1 SH2 domain GLE1 PF07817.8 ETO04116.1 - 0.07 12.0 0.2 0.99 8.2 0.0 2.0 1 1 1 2 2 2 0 GLE1-like protein Pox_RNA_Pol_19 PF05320.7 ETO04119.1 - 0.025 14.3 4.2 0.013 15.2 1.4 1.5 1 1 1 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit PIH1 PF08190.7 ETO04119.1 - 0.79 9.0 9.8 1.1 8.5 6.8 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 GET2 PF08690.5 ETO04119.1 - 2.7 7.1 6.1 2.9 7.0 4.2 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Ndc1_Nup PF09531.5 ETO04119.1 - 6.3 5.0 7.1 6.9 4.9 4.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CEP19 PF14933.1 ETO04119.1 - 8.5 6.6 10.1 15 5.8 7.0 1.5 1 1 0 1 1 1 0 CEP19-like protein IncA PF04156.9 ETO04120.1 - 0.005 16.4 7.0 0.0062 16.1 4.8 1.1 1 0 0 1 1 1 1 IncA protein CENP-F_leu_zip PF10473.4 ETO04120.1 - 0.0086 15.9 6.7 0.02 14.7 3.2 1.9 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rab5-bind PF09311.6 ETO04120.1 - 0.021 14.7 6.1 0.021 14.7 4.2 1.6 2 0 0 2 2 2 0 Rabaptin-like protein KLRAQ PF10205.4 ETO04120.1 - 0.071 13.1 3.9 0.097 12.7 2.7 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein APG6 PF04111.7 ETO04120.1 - 0.13 11.3 5.9 0.14 11.1 4.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Wbp11 PF09429.5 ETO04120.1 - 0.19 11.7 4.8 0.63 10.0 1.2 2.2 1 1 1 2 2 2 0 WW domain binding protein 11 Sec2p PF06428.6 ETO04120.1 - 0.31 10.9 5.8 0.15 11.9 1.4 2.1 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p YlqD PF11068.3 ETO04120.1 - 2.3 8.2 8.6 0.75 9.8 3.6 1.8 1 1 1 2 2 2 0 YlqD protein DUF972 PF06156.8 ETO04120.1 - 4.5 7.6 8.8 22 5.4 6.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF972) FlxA PF14282.1 ETO04120.1 - 9.8 6.1 14.0 1.7e+02 2.2 9.7 2.1 1 1 0 1 1 1 0 FlxA-like protein RabGAP-TBC PF00566.13 ETO04121.1 - 1.1e-16 60.9 1.8 1.3e-16 60.7 1.3 1.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SicP-binding PF09119.5 ETO04121.1 - 0.13 11.9 0.1 1.3 8.7 0.0 2.1 2 0 0 2 2 2 0 SicP binding CAF1-p150_C2 PF15539.1 ETO04123.1 - 1.4 8.0 5.4 1.2 8.2 3.3 1.2 1 1 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term RCC1_2 PF13540.1 ETO04124.1 - 1.8e-18 65.6 10.6 1.9e-06 27.3 1.1 3.2 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 ETO04124.1 - 8.2e-13 48.3 0.1 0.0067 16.6 0.1 3.9 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat Sema PF01403.14 ETO04124.1 - 0.03 12.8 0.3 0.044 12.2 0.2 1.2 1 0 0 1 1 1 0 Sema domain MatE PF01554.13 ETO04125.1 - 0.011 15.4 0.3 0.011 15.4 0.2 2.0 2 0 0 2 2 2 0 MatE DUF848 PF05852.6 ETO04125.1 - 0.088 12.6 2.2 0.15 11.8 1.2 1.5 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) SieB PF14163.1 ETO04125.1 - 0.82 9.2 5.2 5.1 6.6 3.6 1.9 1 1 0 1 1 1 0 Superinfection exclusion protein B Sporozoite_P67 PF05642.6 ETO04127.1 - 3.2 5.5 16.4 5.1 4.8 11.5 1.4 1 1 0 1 1 1 0 Sporozoite P67 surface antigen MMR_HSR1 PF01926.18 ETO04128.1 - 0.0071 16.2 3.8 0.0095 15.8 2.5 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase ORF6C PF10552.4 ETO04128.1 - 0.24 11.1 10.1 0.71 9.6 1.7 2.5 1 1 1 2 2 2 0 ORF6C domain CNP1 PF08750.6 ETO04129.1 - 0.031 13.9 0.3 0.041 13.5 0.2 1.3 1 0 0 1 1 1 0 CNP1-like family Oxygenase-NA PF09859.4 ETO04129.1 - 0.038 13.2 1.7 0.14 11.4 0.4 1.9 1 1 1 2 2 2 0 Oxygenase, catalysing oxidative methylation of damaged DNA TMF_TATA_bd PF12325.3 ETO04129.1 - 0.77 9.4 9.7 0.99 9.1 6.7 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding FlxA PF14282.1 ETO04129.1 - 1.2 9.0 6.5 2.3 8.1 4.3 1.7 1 1 0 1 1 1 0 FlxA-like protein Spc7 PF08317.6 ETO04130.1 - 0.011 14.4 5.2 0.013 14.1 3.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Striatin PF08232.7 ETO04130.1 - 0.011 15.9 0.2 0.011 15.9 0.1 2.1 1 1 1 2 2 2 0 Striatin family Hrs_helical PF12210.3 ETO04130.1 - 0.032 14.4 0.8 0.051 13.8 0.6 1.3 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF904 PF06005.7 ETO04130.1 - 0.064 13.5 0.1 0.064 13.5 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DivIC PF04977.10 ETO04130.1 - 0.13 11.8 4.1 0.4 10.2 0.5 2.4 1 1 1 2 2 2 0 Septum formation initiator Cep57_MT_bd PF06657.8 ETO04130.1 - 1.1 9.2 4.6 0.88 9.5 0.2 2.3 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 SR-25 PF10500.4 ETO04130.1 - 3.3 7.1 14.0 1.1 8.6 7.8 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein BLOC1_2 PF10046.4 ETO04132.1 - 0.0077 16.3 2.9 0.009 16.1 1.1 1.8 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 TarH PF02203.10 ETO04132.1 - 0.17 11.6 2.6 0.23 11.2 1.8 1.1 1 0 0 1 1 1 0 Tar ligand binding domain homologue DUF1387 PF07139.6 ETO04132.1 - 1.9 8.0 9.1 2.3 7.7 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Pox_Ag35 PF03286.9 ETO04132.1 - 2.5 7.5 9.1 3 7.2 6.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Maf1 PF09174.5 ETO04132.1 - 8.5 6.1 14.5 6.7 6.5 4.4 2.2 2 0 0 2 2 2 0 Maf1 regulator DUF2381 PF09544.5 ETO04133.1 - 0.039 13.0 1.5 0.058 12.5 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) LCD1 PF09798.4 ETO04133.1 - 0.075 11.0 14.9 0.089 10.7 10.4 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein Secretin_N_2 PF07655.8 ETO04133.1 - 0.16 12.4 21.8 0.29 11.5 4.1 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain Med13_N PF11597.3 ETO04133.1 - 0.42 9.2 9.5 0.54 8.8 6.2 1.5 1 1 0 1 1 1 0 Mediator complex subunit 13 N-terminal DUF4484 PF14831.1 ETO04133.1 - 9.5 6.2 10.5 3.7 7.6 3.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4484) DUF3301 PF11743.3 ETO04135.1 - 0.025 14.0 0.3 0.043 13.3 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3301) EF-hand_1 PF00036.27 ETO04137.1 - 2.4e-07 29.5 0.1 4.3e-07 28.7 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 ETO04137.1 - 2.3e-05 24.4 0.0 3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO04137.1 - 5.5e-05 22.7 0.1 0.00011 21.7 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.1 ETO04137.1 - 0.00016 21.2 0.1 0.00024 20.6 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 ETO04137.1 - 0.00051 19.2 0.4 0.00093 18.4 0.3 1.5 1 0 0 1 1 1 1 EF hand SPARC_Ca_bdg PF10591.4 ETO04137.1 - 0.025 14.5 0.4 0.053 13.5 0.3 1.6 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Nsp1_C PF05064.8 ETO04138.1 - 0.00096 18.7 0.3 0.0042 16.6 0.1 2.3 1 1 1 2 2 2 1 Nsp1-like C-terminal region MIT PF04212.13 ETO04140.1 - 1.8e-13 50.1 0.5 1.8e-13 50.1 0.3 1.7 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain DUF234 PF03008.9 ETO04140.1 - 0.11 12.6 0.3 0.15 12.1 0.2 1.3 1 0 0 1 1 1 0 Archaea bacterial proteins of unknown function PGA2 PF07543.7 ETO04140.1 - 0.31 10.8 6.1 0.39 10.5 4.2 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 RGS PF00615.14 ETO04141.1 - 0.024 14.7 1.7 0.046 13.8 1.2 1.7 1 1 0 1 1 1 0 Regulator of G protein signaling domain SdrG_C_C PF10425.4 ETO04141.1 - 0.07 13.0 0.0 0.079 12.9 0.0 1.2 1 0 0 1 1 1 0 C-terminus of bacterial fibrinogen-binding adhesin Herpes_LMP2 PF07415.6 ETO04142.1 - 1.8 7.0 3.1 2.6 6.5 2.1 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein THF_DHG_CYH_C PF02882.14 ETO04144.1 - 1.9e-28 98.5 0.1 7.2e-27 93.4 0.1 2.0 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Chordopox_G3 PF06129.7 ETO04144.1 - 0.016 15.3 0.0 0.016 15.3 0.0 1.4 2 0 0 2 2 2 0 Chordopoxvirus G3 protein DEAD PF00270.24 ETO04145.1 - 6.9e-05 22.4 0.0 0.00018 21.0 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF1631 PF07793.6 ETO04145.1 - 0.012 13.7 0.1 0.015 13.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DUF2413 PF10310.4 ETO04146.1 - 0.4 9.4 12.3 0.43 9.3 8.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) B56 PF01603.15 ETO04148.1 - 8.3e-60 202.5 3.5 9e-60 202.3 2.4 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) COG6 PF06419.6 ETO04149.1 - 0.023 12.8 0.3 0.025 12.7 0.2 1.0 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 WavE PF07507.6 ETO04150.1 - 0.07 12.0 0.1 0.08 11.8 0.1 1.1 1 0 0 1 1 1 0 WavE lipopolysaccharide synthesis DUF4463 PF14703.1 ETO04150.1 - 1.1 9.8 4.2 0.48 10.9 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) AAA_16 PF13191.1 ETO04151.1 - 1.6e-06 28.2 0.0 2.1e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 ETO04151.1 - 0.0013 17.6 0.2 0.0021 16.9 0.1 1.4 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.1 ETO04151.1 - 0.0016 18.6 0.0 0.038 14.1 0.0 2.1 1 1 1 2 2 2 1 AAA domain DAP3 PF10236.4 ETO04151.1 - 0.0038 16.1 0.0 0.0066 15.4 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 Arch_ATPase PF01637.13 ETO04151.1 - 0.028 14.1 0.1 0.057 13.0 0.0 1.7 2 0 0 2 2 2 0 Archaeal ATPase AAA_18 PF13238.1 ETO04151.1 - 0.028 14.7 0.1 0.089 13.1 0.0 1.9 3 0 0 3 3 3 0 AAA domain AAA_PrkA PF08298.6 ETO04151.1 - 0.086 11.5 0.0 0.086 11.5 0.0 1.1 1 0 0 1 1 1 0 PrkA AAA domain DUF4064 PF13273.1 ETO04152.1 - 0.019 15.0 5.7 0.069 13.2 1.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF423 PF04241.10 ETO04152.1 - 0.68 9.8 4.0 6.8 6.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF423) G-alpha PF00503.15 ETO04154.1 - 2.1e-08 33.2 0.8 2.3e-08 33.1 0.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit DUF1281 PF06924.6 ETO04154.1 - 0.0094 15.3 0.2 0.047 13.0 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1281) CLPTM1 PF05602.7 ETO04155.1 - 2.7 6.6 6.3 3.3 6.3 4.4 1.2 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) RNA_pol_L_2 PF13656.1 ETO04156.1 - 0.0026 17.1 1.0 0.0054 16.1 0.7 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF2383 PF09537.5 ETO04156.1 - 0.0044 17.2 4.3 0.0044 17.2 3.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF2383) Toxin_52 PF15605.1 ETO04156.1 - 0.25 11.2 4.9 0.08 12.8 0.8 2.0 1 1 1 2 2 2 0 Putative toxin 52 Cep57_CLD PF14073.1 ETO04156.1 - 0.57 9.9 25.3 0.71 9.6 17.5 1.1 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 DUF3479 PF11965.3 ETO04156.1 - 0.6 9.8 5.3 0.2 11.4 0.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3479) DUF3231 PF11553.3 ETO04156.1 - 1.3 8.4 6.1 0.32 10.4 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3231) Ribosomal_S6 PF01250.12 ETO04156.1 - 1.4 8.8 5.2 0.39 10.6 1.0 1.9 2 0 0 2 2 2 0 Ribosomal protein S6 CorA PF01544.13 ETO04156.1 - 2 7.3 16.0 1.5 7.7 10.2 1.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein CDC37_N PF03234.9 ETO04156.1 - 4 7.7 18.2 6.8 6.9 12.6 1.4 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding SPT16 PF08644.6 ETO04156.1 - 7.8 6.3 13.3 5.1 6.9 7.8 1.7 1 1 1 2 2 2 0 FACT complex subunit (SPT16/CDC68) DNA_pol_B_exo1 PF03104.14 ETO04158.1 - 1.2e-28 99.8 0.0 1.5e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_exo2 PF10108.4 ETO04158.1 - 3.9e-09 36.3 0.7 3.8e-08 33.1 0.5 2.0 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 ETO04158.1 - 0.00012 21.9 0.6 0.00095 19.0 0.4 2.4 1 1 0 1 1 1 1 RNase_H superfamily Colipase-like PF15083.1 ETO04160.1 - 0.11 12.4 0.7 0.2 11.6 0.5 1.4 1 0 0 1 1 1 0 Colipase-like DUF566 PF04484.7 ETO04161.1 - 0.017 14.6 3.9 0.018 14.5 2.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF566) ASD1 PF08688.5 ETO04161.1 - 0.035 13.8 0.8 0.045 13.5 0.6 1.3 1 0 0 1 1 1 0 Apx/Shroom domain ASD1 DUF2217 PF10265.4 ETO04161.1 - 1.2 7.7 4.2 1.4 7.6 2.9 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Macoilin PF09726.4 ETO04161.1 - 1.3 7.2 7.5 1.5 6.9 5.2 1.0 1 0 0 1 1 1 0 Transmembrane protein MAP65_ASE1 PF03999.7 ETO04161.1 - 5.8 5.3 8.7 6.9 5.1 6.0 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) UCH PF00443.24 ETO04162.1 - 5.6e-31 107.6 0.1 6.6e-31 107.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO04162.1 - 4.6e-07 29.5 0.0 6.6e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Hydrolase PF00702.21 ETO04164.1 - 1e-06 29.3 0.0 1.3e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETO04164.1 - 0.0072 16.5 0.0 0.044 13.9 0.0 1.8 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase SAC3_GANP PF03399.11 ETO04164.1 - 0.04 13.4 0.0 0.049 13.1 0.0 1.1 1 0 0 1 1 1 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family ATP-synt_E_2 PF08112.6 ETO04164.1 - 0.078 13.0 0.4 0.15 12.1 0.3 1.4 1 0 0 1 1 1 0 ATP synthase epsilon subunit Sigma70_r1_1 PF03979.9 ETO04164.1 - 0.078 12.9 0.4 2.7 7.9 0.1 2.4 1 1 1 2 2 2 0 Sigma-70 factor, region 1.1 KorB PF08535.5 ETO04164.1 - 0.092 12.9 0.2 0.14 12.3 0.1 1.2 1 0 0 1 1 1 0 KorB domain DUF1015 PF06245.6 ETO04167.1 - 5.5e-37 127.2 0.1 8.3e-37 126.6 0.0 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1015) DUF972 PF06156.8 ETO04168.1 - 0.0026 18.1 9.1 0.045 14.0 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF972) IncA PF04156.9 ETO04168.1 - 0.0067 16.0 12.7 0.01 15.4 8.8 1.3 1 0 0 1 1 1 1 IncA protein HALZ PF02183.13 ETO04168.1 - 0.011 15.3 8.0 0.14 11.9 0.0 2.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper Tropomyosin_1 PF12718.2 ETO04168.1 - 0.013 15.3 11.7 0.013 15.3 8.1 1.9 2 0 0 2 2 2 0 Tropomyosin like DUF904 PF06005.7 ETO04168.1 - 0.04 14.2 21.6 1.2 9.4 9.2 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF904) Hemerythrin PF01814.18 ETO04168.1 - 0.043 13.9 0.9 0.15 12.1 0.4 1.8 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain ERM PF00769.14 ETO04168.1 - 0.067 12.7 16.0 3.3 7.1 0.0 2.0 2 0 0 2 2 2 0 Ezrin/radixin/moesin family bZIP_1 PF00170.16 ETO04168.1 - 0.1 12.5 0.2 0.1 12.5 0.1 3.3 4 0 0 4 4 3 0 bZIP transcription factor CENP-F_leu_zip PF10473.4 ETO04168.1 - 0.12 12.2 15.6 0.82 9.5 0.2 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.3 ETO04168.1 - 0.17 11.7 17.5 0.72 9.6 0.0 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding YjcZ PF13990.1 ETO04168.1 - 0.19 10.8 4.5 0.11 11.6 1.1 1.8 1 1 1 2 2 2 0 YjcZ-like protein BRE1 PF08647.6 ETO04168.1 - 0.21 11.5 11.3 0.7 9.9 6.4 2.0 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF1539 PF07560.6 ETO04168.1 - 0.23 11.3 6.9 3.1 7.6 0.1 2.1 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1539) GAS PF13851.1 ETO04168.1 - 0.41 9.7 13.9 2.4 7.2 9.8 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.6 ETO04168.1 - 0.47 10.2 17.0 1.5 8.6 0.5 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) APG6 PF04111.7 ETO04168.1 - 1.8 7.5 19.6 4.6 6.2 9.9 2.0 1 1 0 2 2 2 0 Autophagy protein Apg6 CCDC92 PF14916.1 ETO04168.1 - 2.7 7.6 10.9 0.12 11.9 1.3 3.0 3 1 1 4 4 4 0 Coiled-coil domain of unknown function DegS PF05384.6 ETO04168.1 - 5.8 6.0 11.7 6 6.0 4.7 2.2 1 1 1 2 2 2 0 Sensor protein DegS TMF_TATA_bd PF12325.3 ETO04168.1 - 6.2 6.5 16.5 1.2 8.8 0.3 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding bZIP_2 PF07716.10 ETO04168.1 - 6.9 6.5 15.3 5.3 6.9 0.0 3.5 3 0 0 3 3 3 0 Basic region leucine zipper ADIP PF11559.3 ETO04168.1 - 7 6.5 15.8 5.4 6.9 0.1 2.4 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2373 PF10180.4 ETO04169.1 - 0.1 12.1 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Macro PF01661.16 ETO04170.1 - 2.7e-11 43.3 0.0 5.4e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Macro domain FYRN PF05964.9 ETO04171.1 - 2.5e-11 42.8 0.2 4.3e-11 42.0 0.1 1.4 1 0 0 1 1 1 1 F/Y-rich N-terminus Pkinase PF00069.20 ETO04172.1 - 0.00024 20.3 0.1 0.00034 19.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Apis_Csd PF11671.3 ETO04173.1 - 0.62 9.8 4.0 0.27 11.0 1.3 1.6 2 0 0 2 2 2 0 Complementary sex determiner protein DUF3474 PF11960.3 ETO04174.1 - 1.7 8.6 4.6 2.6 8.0 3.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3474) TFIIF_alpha PF05793.7 ETO04174.1 - 4.4 5.5 24.6 4.8 5.4 17.1 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Herpes_UL25 PF01499.11 ETO04174.1 - 4.6 5.4 12.8 5.1 5.2 8.9 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family Ribosomal_60s PF00428.14 ETO04174.1 - 5.9 7.3 14.5 4.3 7.7 9.3 1.5 1 1 0 1 1 1 0 60s Acidic ribosomal protein AA_permease PF00324.16 ETO04177.1 - 1.2e-15 56.8 16.2 1.4e-15 56.5 11.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETO04177.1 - 0.018 13.5 15.0 0.043 12.3 10.2 1.6 1 1 1 2 2 2 0 Amino acid permease DUF3099 PF11298.3 ETO04177.1 - 0.12 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) zf-DHHC PF01529.15 ETO04177.1 - 0.34 10.2 2.8 0.21 10.9 0.7 1.6 1 1 1 2 2 2 0 DHHC palmitoyltransferase DUF2207 PF09972.4 ETO04177.1 - 0.72 8.3 2.4 0.51 8.8 0.9 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3671 PF12420.3 ETO04177.1 - 1.3 9.0 8.7 4.6 7.2 6.1 1.9 1 1 0 1 1 1 0 Protein of unknown function AAA_6 PF12774.2 ETO04178.1 - 9.4e-24 84.2 0.1 1.8e-23 83.3 0.0 1.5 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 DUF258 PF03193.11 ETO04178.1 - 0.0027 16.9 0.1 0.0044 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Virul_Fac PF10139.4 ETO04178.1 - 0.018 13.0 0.0 0.023 12.6 0.0 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor T2SE PF00437.15 ETO04178.1 - 0.02 13.8 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein MobB PF03205.9 ETO04178.1 - 0.022 14.4 0.1 0.17 11.6 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B EPO_TPO PF00758.13 ETO04178.1 - 0.06 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Erythropoietin/thrombopoietin cNMP_binding PF00027.24 ETO04180.1 - 2.1e-16 59.4 0.0 3.6e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF177 PF02620.12 ETO04181.1 - 0.06 13.3 7.2 0.19 11.7 4.5 2.2 1 1 0 1 1 1 0 Uncharacterized ACR, COG1399 DUF1387 PF07139.6 ETO04181.1 - 0.22 11.0 19.1 0.26 10.8 13.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) SOBP PF15279.1 ETO04181.1 - 1.5 9.1 6.1 2 8.7 4.3 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Protocadherin PF08374.6 ETO04181.1 - 6.7 6.2 12.6 1 8.9 5.3 1.8 1 1 1 2 2 2 0 Protocadherin PPR_2 PF13041.1 ETO04182.1 - 8.4e-10 38.4 0.1 6.5e-05 22.8 0.0 3.0 1 1 2 3 3 3 3 PPR repeat family PPR_3 PF13812.1 ETO04182.1 - 1.1e-05 25.3 0.8 0.25 11.7 0.0 3.4 3 1 0 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.15 ETO04182.1 - 2.9e-05 23.7 2.0 0.62 10.1 0.1 3.2 3 0 0 3 3 3 2 PPR repeat Brix PF04427.13 ETO04183.1 - 0.0019 17.8 1.6 0.0021 17.7 0.0 1.9 2 1 0 2 2 2 1 Brix domain DUF188 PF02639.9 ETO04183.1 - 0.0062 15.9 1.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized BCR, YaiI/YqxD family COG1671 Lipase_GDSL_3 PF14606.1 ETO04183.1 - 0.2 11.3 0.8 0.32 10.7 0.6 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family alpha-hel2 PF14456.1 ETO04183.1 - 0.57 8.9 3.9 0.7 8.6 2.7 1.2 1 0 0 1 1 1 0 Alpha-helical domain 2 Dynein_heavy PF03028.10 ETO04183.1 - 2 6.3 6.7 2.2 6.1 4.7 1.2 1 0 0 1 1 1 0 Dynein heavy chain and region D6 of dynein motor PIG-H PF10181.4 ETO04184.1 - 0.047 13.3 0.2 0.072 12.7 0.1 1.4 1 0 0 1 1 1 0 GPI-GlcNAc transferase complex, PIG-H component R3H-assoc PF13902.1 ETO04185.1 - 0.073 13.0 3.8 0.086 12.8 2.7 1.1 1 0 0 1 1 1 0 R3H-associated N-terminal domain Hep_59 PF07052.6 ETO04185.1 - 0.29 11.5 9.2 0.042 14.2 2.4 2.0 1 1 1 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 APC_CDC26 PF10471.4 ETO04185.1 - 0.4 11.4 5.9 0.97 10.2 1.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF912 PF06024.7 ETO04185.1 - 2.1 8.4 5.0 1.2 9.2 1.4 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Ank PF00023.25 ETO04186.1 - 1.3e-16 59.4 1.9 2.6e-07 30.1 0.0 3.7 4 1 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 ETO04186.1 - 1.5e-16 60.4 0.3 4.7e-08 33.2 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO04186.1 - 8e-16 58.0 0.3 2.9e-07 30.8 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO04186.1 - 2.2e-14 52.1 0.2 3.7e-06 26.6 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 ETO04186.1 - 6.3e-14 51.6 0.0 2.9e-07 30.5 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) NRDE PF05742.7 ETO04186.1 - 0.038 13.2 0.0 0.048 12.9 0.0 1.1 1 0 0 1 1 1 0 NRDE protein PUF PF00806.14 ETO04186.1 - 0.046 13.2 0.0 0.69 9.5 0.0 2.4 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat RhoGAP PF00620.22 ETO04187.1 - 1.6e-15 57.0 0.0 2.5e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain CENP-B_dimeris PF09026.5 ETO04187.1 - 0.044 14.0 0.3 0.066 13.4 0.2 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DEP PF00610.16 ETO04188.1 - 2.6e-12 46.2 0.1 3.8e-12 45.7 0.1 1.3 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PsbQ PF05757.6 ETO04189.1 - 0.0094 15.3 0.1 0.016 14.6 0.1 1.3 1 0 0 1 1 1 1 Oxygen evolving enhancer protein 3 (PsbQ) Focal_AT PF03623.8 ETO04189.1 - 0.034 13.6 0.2 0.044 13.2 0.1 1.2 1 0 0 1 1 1 0 Focal adhesion targeting region Mad3_BUB1_I PF08311.7 ETO04191.1 - 0.02 14.6 2.1 0.021 14.6 0.5 1.8 2 1 0 2 2 2 0 Mad3/BUB1 homology region 1 TPR_12 PF13424.1 ETO04191.1 - 0.026 14.4 0.1 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Cas_Cas02710 PF09670.5 ETO04191.1 - 0.033 12.8 0.9 0.04 12.5 0.6 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) SPT16 PF08644.6 ETO04191.1 - 0.1 12.4 0.2 0.14 11.9 0.2 1.2 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) DUF912 PF06024.7 ETO04192.1 - 0.1 12.6 3.4 0.11 12.5 2.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pro_dh-DNA_bdg PF14850.1 ETO04193.1 - 0.11 12.7 0.5 0.23 11.6 0.3 1.5 1 0 0 1 1 1 0 DNA-binding domain of Proline dehydrogenase Agouti PF05039.7 ETO04193.1 - 2.2 8.6 5.0 12 6.2 0.1 2.4 2 0 0 2 2 2 0 Agouti protein NST1 PF13945.1 ETO04193.1 - 9.6 6.2 18.4 3.4 7.6 7.8 2.2 2 0 0 2 2 2 0 Salt tolerance down-regulator UQ_con PF00179.21 ETO04195.1 - 1.4e-14 53.6 0.2 1.4e-14 53.6 0.2 2.0 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme RWD PF05773.17 ETO04195.1 - 0.46 10.3 3.2 0.63 9.9 2.2 1.5 1 1 0 1 1 1 0 RWD domain CDC45 PF02724.9 ETO04196.1 - 0.0023 16.0 15.0 0.0027 15.8 10.4 1.0 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.7 ETO04196.1 - 0.0041 15.1 22.5 0.0042 15.0 15.6 1.1 1 0 0 1 1 1 1 Nop14-like family Pilt PF15453.1 ETO04196.1 - 0.011 15.3 2.5 0.011 15.3 1.7 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions SDA1 PF05285.7 ETO04196.1 - 0.026 13.8 22.1 0.029 13.6 15.3 1.0 1 0 0 1 1 1 0 SDA1 Prothymosin PF03247.9 ETO04196.1 - 0.028 14.5 31.9 0.042 14.0 22.1 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family Peptidase_M66 PF10462.4 ETO04196.1 - 0.031 13.1 0.0 0.04 12.7 0.0 1.1 1 0 0 1 1 1 0 Peptidase M66 Daxx PF03344.10 ETO04196.1 - 0.18 10.2 25.3 0.19 10.2 17.5 1.1 1 0 0 1 1 1 0 Daxx Family HSP90 PF00183.13 ETO04196.1 - 0.27 9.5 14.9 0.29 9.4 10.4 1.1 1 0 0 1 1 1 0 Hsp90 protein VID27 PF08553.5 ETO04196.1 - 0.97 7.5 14.8 0.96 7.5 10.3 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF2457 PF10446.4 ETO04196.1 - 1.2 7.8 26.8 1.2 7.7 18.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF1510 PF07423.6 ETO04196.1 - 2.2 7.6 17.5 2.6 7.3 12.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NOA36 PF06524.7 ETO04196.1 - 3.5 6.7 18.1 4.4 6.4 12.5 1.3 1 0 0 1 1 1 0 NOA36 protein Merozoite_SPAM PF07133.6 ETO04196.1 - 6 6.7 30.6 7.3 6.4 21.2 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CobT PF06213.7 ETO04196.1 - 7 5.6 22.7 7.9 5.5 15.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Paf1 PF03985.8 ETO04196.1 - 7.4 5.2 22.7 9.1 4.8 15.7 1.1 1 0 0 1 1 1 0 Paf1 DUF2890 PF11081.3 ETO04196.1 - 7.7 6.5 14.0 9.9 6.1 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) IFT57 PF10498.4 ETO04196.1 - 8.1 5.0 13.2 9.3 4.8 9.2 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF2722 PF10846.3 ETO04196.1 - 8.2 5.3 11.3 9.7 5.0 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RRN3 PF05327.6 ETO04196.1 - 8.3 4.3 15.4 9.4 4.2 10.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Kelch_6 PF13964.1 ETO04198.1 - 9.3e-06 25.6 1.3 0.018 15.1 0.3 2.8 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.20 ETO04198.1 - 1.7e-05 24.2 7.7 0.00035 20.0 1.3 3.1 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO04198.1 - 0.00022 21.0 6.2 0.056 13.4 0.8 3.7 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 ETO04198.1 - 0.0011 19.0 0.3 0.011 15.8 0.0 2.6 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO04198.1 - 0.016 14.9 1.7 4.7 7.1 0.1 2.8 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.1 ETO04198.1 - 0.03 14.0 0.1 0.03 14.0 0.1 2.6 3 0 0 3 3 3 0 Galactose oxidase, central domain PGBA_N PF15436.1 ETO04198.1 - 0.083 12.1 0.1 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA N-terminal DUF2968 PF11180.3 ETO04199.1 - 0.0014 18.0 0.3 0.0023 17.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) BBS2_Mid PF14783.1 ETO04199.1 - 0.069 12.9 0.2 2.8 7.7 0.0 2.2 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region mRNA_stabil PF13929.1 ETO04199.1 - 0.11 11.3 0.6 0.46 9.3 0.4 1.9 1 1 0 1 1 1 0 mRNA stabilisation ALIX_LYPXL_bnd PF13949.1 ETO04201.1 - 0.001 18.1 12.9 0.0019 17.2 9.0 1.5 1 1 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF812 PF05667.6 ETO04201.1 - 0.017 13.6 11.8 0.021 13.3 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) BLOC1_2 PF10046.4 ETO04201.1 - 0.018 15.1 7.0 0.018 15.1 4.8 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GvpK PF05121.7 ETO04201.1 - 0.022 14.5 6.4 0.24 11.2 0.5 2.5 1 1 2 3 3 3 0 Gas vesicle protein K DASH_Dad3 PF08656.5 ETO04201.1 - 0.026 14.2 9.2 0.41 10.3 0.9 2.8 1 1 1 2 2 2 0 DASH complex subunit Dad3 DUF1476 PF07345.6 ETO04201.1 - 0.033 14.4 1.3 4.1 7.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1476) APG6 PF04111.7 ETO04201.1 - 0.033 13.2 14.4 0.043 12.8 10.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Mnd1 PF03962.10 ETO04201.1 - 0.039 13.6 15.5 0.03 13.9 5.6 2.1 1 1 1 2 2 2 0 Mnd1 family DUF1843 PF08898.5 ETO04201.1 - 0.049 13.6 0.4 0.049 13.6 0.2 3.0 4 0 0 4 4 2 0 Domain of unknown function (DUF1843) Imm29 PF15575.1 ETO04201.1 - 0.078 12.5 0.3 0.17 11.4 0.0 1.6 2 0 0 2 2 2 0 Immunity protein 29 RNase_E_G PF10150.4 ETO04201.1 - 0.17 11.0 6.7 0.14 11.3 2.0 2.1 1 1 1 2 2 2 0 Ribonuclease E/G family Rota_NSP4 PF01452.11 ETO04201.1 - 0.17 11.1 4.6 0.29 10.4 3.2 1.4 1 0 0 1 1 1 0 Rotavirus non structural protein DUF3450 PF11932.3 ETO04201.1 - 0.17 11.0 5.7 0.16 11.1 3.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Baculo_PEP_C PF04513.7 ETO04201.1 - 0.23 11.2 3.7 0.17 11.6 1.4 1.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IFT57 PF10498.4 ETO04201.1 - 0.33 9.6 15.1 0.39 9.3 10.5 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 GCR PF02155.10 ETO04201.1 - 0.34 9.6 5.5 0.38 9.4 3.8 1.1 1 0 0 1 1 1 0 Glucocorticoid receptor Reo_sigmaC PF04582.7 ETO04201.1 - 0.35 9.9 4.3 0.43 9.7 3.0 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Syntaxin-6_N PF09177.6 ETO04201.1 - 0.42 11.0 8.4 0.73 10.2 4.5 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF4164 PF13747.1 ETO04201.1 - 0.53 10.4 6.0 0.5 10.5 1.0 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) Cep57_MT_bd PF06657.8 ETO04201.1 - 0.59 10.1 11.2 2.8 7.9 3.0 2.9 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 ADIP PF11559.3 ETO04201.1 - 0.6 10.0 20.0 0.85 9.5 10.2 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 ETO04201.1 - 0.6 9.8 18.3 8 6.2 12.5 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein BTV_NS2 PF04514.7 ETO04201.1 - 0.65 8.8 7.4 0.73 8.6 5.1 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF3573 PF12097.3 ETO04201.1 - 0.76 8.3 7.8 0.9 8.0 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) ING PF12998.2 ETO04201.1 - 0.8 10.0 14.6 23 5.3 10.1 2.1 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding V_ATPase_I PF01496.14 ETO04201.1 - 0.87 7.3 11.7 0.94 7.2 8.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2408 PF10303.4 ETO04201.1 - 1.1 9.3 11.6 0.15 12.1 3.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) DASH_Dam1 PF08653.5 ETO04201.1 - 1.2 8.8 8.3 5.4 6.8 0.3 3.2 1 1 2 3 3 3 0 DASH complex subunit Dam1 Peptidase_S46 PF10459.4 ETO04201.1 - 1.3 7.2 6.8 1.3 7.3 4.7 1.1 1 0 0 1 1 1 0 Peptidase S46 MCPsignal PF00015.16 ETO04201.1 - 1.4 8.4 6.5 1.7 8.1 3.8 1.6 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Occludin_ELL PF07303.8 ETO04201.1 - 2 9.1 11.9 1 10.1 4.3 2.2 1 1 1 2 2 2 0 Occludin homology domain IncA PF04156.9 ETO04201.1 - 2.6 7.5 19.7 3.6 7.1 11.5 2.0 1 1 1 2 2 2 0 IncA protein DUF3635 PF12330.3 ETO04201.1 - 2.7 8.1 7.1 0.55 10.3 0.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3635) DUF4200 PF13863.1 ETO04201.1 - 3.3 7.6 18.3 0.16 11.8 5.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) EAP30 PF04157.11 ETO04201.1 - 5.9 5.9 10.9 0.16 11.0 1.4 2.0 2 0 0 2 2 2 0 EAP30/Vps36 family Cep57_CLD_2 PF14197.1 ETO04201.1 - 8.5 6.3 11.7 17 5.4 1.5 2.9 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 CLPTM1 PF05602.7 ETO04202.1 - 8e-54 183.0 14.7 1.3e-53 182.3 10.2 1.3 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) SBF PF01758.11 ETO04202.1 - 0.017 14.4 1.6 0.11 11.8 0.1 2.6 2 0 0 2 2 2 0 Sodium Bile acid symporter family PQ-loop PF04193.9 ETO04202.1 - 0.96 9.0 9.9 2.9 7.5 0.3 4.1 3 1 1 4 4 4 0 PQ loop repeat cNMP_binding PF00027.24 ETO04203.1 - 9.2e-31 105.5 0.6 8.9e-10 38.2 0.0 4.2 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Adaptin_binding PF10199.4 ETO04203.1 - 0.0018 18.5 4.5 0.0037 17.5 0.4 2.3 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 DUF608 PF04685.8 ETO04203.1 - 0.0029 16.3 0.1 0.005 15.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF608 2OG-FeII_Oxy_2 PF13532.1 ETO04204.1 - 1.2e-11 44.7 0.0 3.1e-11 43.4 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TALPID3 PF15324.1 ETO04204.1 - 0.011 13.1 2.7 0.014 12.7 1.9 1.0 1 0 0 1 1 1 0 Hedgehog signalling target MetRS-N PF09635.5 ETO04204.1 - 0.07 13.5 2.1 0.15 12.4 1.5 1.6 1 0 0 1 1 1 0 MetRS-N binding domain Arteri_nucleo PF01481.11 ETO04204.1 - 1.9 8.6 4.7 1 9.5 0.3 2.2 1 1 1 2 2 2 0 Arterivirus nucleocapsid protein HSP70 PF00012.15 ETO04205.1 - 3.8e-47 160.5 0.0 5.4e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein DUF948 PF06103.6 ETO04206.1 - 0.025 14.4 1.3 4 7.3 0.1 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Spectrin PF00435.16 ETO04206.1 - 0.042 14.1 5.4 8.1 6.7 0.2 3.3 1 1 1 3 3 3 0 Spectrin repeat MCR_C PF04609.7 ETO04206.1 - 0.05 12.3 0.1 0.092 11.5 0.1 1.3 1 1 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C DUF1024 PF06260.7 ETO04206.1 - 0.062 13.4 0.5 0.26 11.4 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1024) RNA_pol_Rpc82 PF05645.8 ETO04206.1 - 0.17 11.4 3.8 0.33 10.4 2.1 1.8 1 1 1 2 2 2 0 RNA polymerase III subunit RPC82 DivIVA PF05103.8 ETO04206.1 - 0.51 10.3 4.7 5.2 7.1 0.8 2.3 1 1 1 2 2 2 0 DivIVA protein PAXIP1_C PF15364.1 ETO04206.1 - 0.81 9.6 8.7 0.78 9.6 1.6 2.6 1 1 1 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein TMF_DNA_bd PF12329.3 ETO04206.1 - 1.5 8.6 4.9 0.44 10.3 0.7 2.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CAP_GLY PF01302.20 ETO04207.1 - 3e-08 33.2 0.0 5.1e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain MIP-T3 PF10243.4 ETO04207.1 - 0.1 11.0 21.1 0.12 10.8 14.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1033 PF06279.6 ETO04207.1 - 1.1 9.0 4.9 0.14 11.9 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1033) KIAA1328 PF15369.1 ETO04208.1 - 1.4 8.6 10.2 1.5 8.5 6.2 1.6 1 1 0 1 1 1 0 Uncharacterised protein KIAA1328 KSR1-SAM PF13543.1 ETO04209.1 - 0.0046 16.7 0.3 0.0072 16.1 0.2 1.3 1 0 0 1 1 1 1 SAM like domain present in kinase suppressor RAS 1 SAM_1 PF00536.25 ETO04209.1 - 0.037 14.2 0.1 0.059 13.5 0.1 1.5 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) Totivirus_coat PF05518.6 ETO04213.1 - 0.14 9.9 0.5 0.14 9.9 0.3 1.0 1 0 0 1 1 1 0 Totivirus coat protein DUF2203 PF09969.4 ETO04213.1 - 0.32 11.2 2.9 0.23 11.6 1.2 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF2365 PF10157.4 ETO04214.1 - 0.0032 17.3 1.1 0.17 11.7 0.3 2.1 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2365) ORF6C PF10552.4 ETO04214.1 - 0.0056 16.4 7.1 0.014 15.1 4.9 1.7 1 0 0 1 1 1 1 ORF6C domain DUF342 PF03961.8 ETO04214.1 - 0.0069 14.8 9.5 0.0077 14.6 6.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) ATG16 PF08614.6 ETO04214.1 - 0.0094 15.7 6.6 0.013 15.3 4.6 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Syntaxin-6_N PF09177.6 ETO04214.1 - 0.025 14.9 2.9 0.025 14.9 2.0 1.8 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Occludin_ELL PF07303.8 ETO04214.1 - 0.073 13.8 5.4 0.15 12.7 3.7 1.5 1 0 0 1 1 1 0 Occludin homology domain Filo_VP35 PF02097.10 ETO04214.1 - 0.28 10.3 6.5 0.36 9.9 4.5 1.1 1 0 0 1 1 1 0 Filoviridae VP35 Mucin PF01456.12 ETO04214.1 - 0.31 10.8 14.3 0.49 10.1 9.9 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Uds1 PF15456.1 ETO04214.1 - 0.31 11.0 3.4 0.21 11.5 0.7 1.8 1 1 0 2 2 2 0 Up-regulated During Septation IncA PF04156.9 ETO04214.1 - 0.35 10.4 5.1 0.2 11.2 2.3 1.4 2 0 0 2 2 2 0 IncA protein PA26 PF04636.8 ETO04214.1 - 0.63 8.6 7.6 0.8 8.3 5.3 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) ETC_C1_NDUFA5 PF04716.9 ETO04214.1 - 1.1 8.8 6.3 0.36 10.3 0.1 2.8 3 0 0 3 3 3 0 ETC complex I subunit conserved region Laminin_II PF06009.7 ETO04214.1 - 1.2 8.9 9.3 0.1 12.3 2.8 1.7 1 1 1 2 2 2 0 Laminin Domain II DUF4425 PF14466.1 ETO04214.1 - 1.8 8.7 11.4 7.5 6.7 7.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4425) Syja_N PF02383.13 ETO04214.1 - 2 7.0 8.7 2.4 6.8 5.4 1.5 1 1 0 1 1 1 0 SacI homology domain Vps51 PF08700.6 ETO04214.1 - 3.3 7.5 9.5 3.9 7.3 0.2 2.5 1 1 1 2 2 2 0 Vps51/Vps67 Osmo_CC PF08946.5 ETO04214.1 - 4.1 7.4 7.1 0.44 10.6 1.6 1.8 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Rsd_AlgQ PF04353.8 ETO04214.1 - 5.2 6.7 9.5 4.6 6.9 0.7 2.4 1 1 1 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ DUF4463 PF14703.1 ETO04214.1 - 5.6 7.5 7.6 1.7 9.2 2.7 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4463) SSP160 PF06933.6 ETO04214.1 - 8.4 4.2 13.3 11 3.8 9.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sipho_Gp157 PF05565.6 ETO04215.1 - 0.014 14.9 2.2 0.018 14.6 1.4 1.4 1 1 0 1 1 1 0 Siphovirus Gp157 DUF190 PF02641.10 ETO04215.1 - 0.025 14.4 1.3 0.038 13.8 0.8 1.4 1 1 0 1 1 1 0 Uncharacterized ACR, COG1993 DUF1792 PF08759.6 ETO04215.1 - 0.064 12.8 0.5 0.065 12.8 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1792) DUF1743 PF08489.6 ETO04215.1 - 0.11 12.2 0.2 0.12 12.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1743) GLE1 PF07817.8 ETO04215.1 - 0.32 9.8 2.8 0.36 9.7 2.0 1.0 1 0 0 1 1 1 0 GLE1-like protein AD PF09793.4 ETO04217.1 - 0.076 12.8 0.3 0.13 12.1 0.2 1.3 1 0 0 1 1 1 0 Anticodon-binding domain WD40 PF00400.27 ETO04219.1 - 3.6e-54 178.8 7.3 2.3e-13 49.4 0.0 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO04219.1 - 1.4e-07 30.0 2.0 0.13 10.3 0.0 4.0 1 1 3 4 4 4 4 Nucleoporin Nup120/160 PD40 PF07676.7 ETO04219.1 - 7.1e-06 25.5 9.2 0.13 11.9 0.1 4.4 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO04219.1 - 3.3e-05 22.8 5.1 0.54 8.9 0.1 3.8 1 1 2 4 4 4 3 Nup133 N terminal like Nbas_N PF15492.1 ETO04219.1 - 0.00018 20.6 1.1 0.29 10.2 0.0 3.1 1 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Pectate_lyase22 PF14583.1 ETO04219.1 - 0.0015 17.0 0.0 0.16 10.3 0.0 2.0 1 1 1 2 2 2 2 Oligogalacturonate lyase POLO_box PF00659.13 ETO04219.1 - 0.004 17.1 1.0 0.62 10.0 0.1 3.2 3 1 0 3 3 3 1 POLO box duplicated region DUF1652 PF07865.6 ETO04219.1 - 0.0068 15.9 0.0 4.9 6.8 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1652) Lipocalin_3 PF12702.2 ETO04219.1 - 0.011 15.7 0.4 3.4 7.7 0.0 3.1 2 1 0 2 2 2 0 Lipocalin-like Resistin PF06954.6 ETO04219.1 - 0.014 15.6 0.2 18 5.7 0.0 3.1 2 1 1 3 3 3 0 Resistin PQQ_2 PF13360.1 ETO04219.1 - 0.03 13.7 0.0 3.7 6.9 0.0 2.5 1 1 1 2 2 2 0 PQQ-like domain eIF2A PF08662.6 ETO04219.1 - 0.032 13.9 0.0 0.81 9.3 0.0 2.3 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF2436 PF10365.4 ETO04219.1 - 0.14 11.7 0.5 14 5.3 0.0 2.9 1 1 3 4 4 4 0 Domain of unknown function (DUF2436) ADP_ribosyl_GH PF03747.9 ETO04220.1 - 2e-38 132.8 0.0 1.1e-37 130.4 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylglycohydrolase IL6 PF00489.12 ETO04221.1 - 0.075 12.6 0.5 0.084 12.4 0.4 1.1 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family Pro_isomerase PF00160.16 ETO04222.1 - 1.8e-53 180.9 0.6 2e-53 180.7 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.10 ETO04223.1 - 1.1e-14 54.1 1.0 2.3e-14 53.1 0.1 2.0 2 0 0 2 2 2 1 U-box domain DUF1972 PF09314.6 ETO04223.1 - 1.6 8.1 7.2 0.34 10.3 1.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1972) WD40 PF00400.27 ETO04224.1 - 0.0014 18.4 0.3 0.0031 17.3 0.0 1.8 2 0 0 2 2 2 1 WD domain, G-beta repeat Toxin_64 PF15542.1 ETO04224.1 - 0.003 18.0 9.9 0.14 12.7 0.3 2.4 2 0 0 2 2 2 2 Putative toxin 64 YbaJ PF10757.4 ETO04224.1 - 0.084 13.0 0.2 0.084 13.0 0.1 2.2 2 0 0 2 2 2 0 Biofilm formation regulator YbaJ Exonuc_VII_L PF02601.10 ETO04224.1 - 0.57 9.3 6.0 0.72 8.9 4.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DapH_N PF08503.5 ETO04224.1 - 1.2 9.3 5.5 25 5.0 0.0 3.3 2 1 1 3 3 3 0 Tetrahydrodipicolinate succinyltransferase N-terminal DUF3911 PF13050.1 ETO04224.1 - 2.8 8.1 5.8 4.5 7.4 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3911) OGG_N PF07934.7 ETO04224.1 - 3.5 7.6 8.9 26 4.8 6.1 2.1 1 1 0 1 1 1 0 8-oxoguanine DNA glycosylase, N-terminal domain GvpH PF05455.6 ETO04225.1 - 0.0093 15.6 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 GvpH DUF2058 PF09831.4 ETO04225.1 - 2.8 7.8 10.7 1.7 8.5 5.0 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) SRP_SPB PF02978.14 ETO04226.1 - 0.14 12.4 5.3 0.054 13.7 1.5 1.7 1 1 1 2 2 2 0 Signal peptide binding domain NPR3 PF03666.8 ETO04226.1 - 3.3 6.1 9.2 3.8 5.9 6.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 HSP90 PF00183.13 ETO04227.1 - 3.8e-68 230.1 8.1 5.1e-68 229.7 5.6 1.0 1 0 0 1 1 1 1 Hsp90 protein UPF0228 PF05727.6 ETO04227.1 - 0.17 11.6 5.2 0.15 11.8 0.2 2.4 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0228) Y_phosphatase3 PF13350.1 ETO04228.1 - 0.00067 19.9 0.7 0.0023 18.1 0.0 2.1 2 1 1 3 3 3 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 ETO04228.1 - 0.0054 16.0 0.5 0.011 15.1 0.0 1.7 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 ETO04228.1 - 0.1 12.6 0.3 0.29 11.1 0.0 1.8 2 0 0 2 2 2 0 Inositol hexakisphosphate HET PF06985.6 ETO04228.1 - 0.15 12.1 1.8 0.23 11.6 1.2 1.6 1 1 0 1 1 1 0 Heterokaryon incompatibility protein (HET) WD40 PF00400.27 ETO04230.1 - 2.9e-58 191.7 17.5 3e-11 42.7 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO04230.1 - 1.7e-09 36.3 1.1 0.0046 15.1 0.0 4.3 2 2 1 3 3 3 3 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO04230.1 - 0.011 15.0 5.7 0.016 14.5 0.5 2.7 2 2 1 3 3 3 0 Domain of unknown function (DUF4221) Kelch_6 PF13964.1 ETO04230.1 - 0.17 12.1 10.7 1.5 9.1 0.1 4.8 5 0 0 5 5 5 0 Kelch motif Kelch_6 PF13964.1 ETO04231.1 - 5.2e-08 32.7 6.5 0.0096 16.0 0.2 4.3 3 1 1 4 4 4 3 Kelch motif Kelch_1 PF01344.20 ETO04231.1 - 1.1e-07 31.2 5.8 0.00015 21.2 0.2 4.8 5 0 0 5 5 5 1 Kelch motif Kelch_5 PF13854.1 ETO04231.1 - 2e-07 30.8 7.0 3.9e-05 23.4 0.7 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 ETO04231.1 - 1.3e-06 28.4 0.3 0.00013 22.0 0.0 3.3 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO04231.1 - 0.00028 20.6 6.5 0.081 12.7 0.2 3.5 2 2 1 3 3 3 2 Galactose oxidase, central domain zf-RING_2 PF13639.1 ETO04234.1 - 1.4e-12 47.2 5.6 3.5e-12 45.9 3.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 ETO04234.1 - 1.8e-07 31.1 2.4 1.8e-07 31.1 1.7 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 ETO04234.1 - 1.1e-05 25.0 4.6 2.3e-05 24.0 3.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 ETO04234.1 - 2.1e-05 24.0 4.9 5.4e-05 22.7 3.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO04234.1 - 2.2e-05 24.3 6.6 0.00017 21.5 4.7 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO04234.1 - 0.00016 21.2 2.6 0.00035 20.1 1.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 ETO04234.1 - 0.00059 19.6 1.5 0.0016 18.2 1.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 ETO04234.1 - 0.0013 18.7 3.9 0.0013 18.6 1.7 1.9 1 1 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 ETO04234.1 - 0.018 14.9 7.5 0.1 12.6 4.9 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.3 ETO04234.1 - 0.13 11.7 1.7 0.35 10.4 1.2 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_1 PF14446.1 ETO04234.1 - 2.6 7.8 6.0 4.2 7.1 3.0 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.24 ETO04234.1 - 4 7.2 7.4 7 6.4 4.0 2.3 1 1 1 2 2 2 0 PHD-finger Asp_Glu_race PF01177.17 ETO04235.1 - 2e-22 80.1 0.0 2.5e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase DUF2393 PF09624.5 ETO04236.1 - 0.055 13.0 0.6 0.19 11.2 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) ERGIC_N PF13850.1 ETO04236.1 - 3 7.8 5.9 20 5.2 0.6 3.4 3 1 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Nop14 PF04147.7 ETO04237.1 - 0.0014 16.6 14.6 0.0019 16.2 10.1 1.1 1 0 0 1 1 1 1 Nop14-like family DUF2457 PF10446.4 ETO04237.1 - 0.003 16.3 18.7 0.0041 15.9 12.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Daxx PF03344.10 ETO04237.1 - 0.0094 14.4 14.6 0.011 14.2 10.1 1.1 1 0 0 1 1 1 1 Daxx Family NOA36 PF06524.7 ETO04237.1 - 1.8 7.7 16.0 3.3 6.8 11.1 1.5 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.5 ETO04237.1 - 5.6 7.2 19.6 19 5.5 12.5 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain NTPase_1 PF03266.10 ETO04238.1 - 1.4e-11 44.3 0.3 2.3e-11 43.6 0.2 1.3 1 0 0 1 1 1 1 NTPase TLV_coat PF00429.14 ETO04238.1 - 0.03 12.7 0.2 0.034 12.5 0.2 1.1 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) FlaG PF03646.10 ETO04238.1 - 2.6 8.2 5.1 1.4 9.0 0.1 2.3 2 1 0 2 2 2 0 FlaG protein FYRC PF05965.9 ETO04239.1 - 0.018 14.8 0.2 0.1 12.4 0.0 1.9 1 1 1 2 2 2 0 F/Y rich C-terminus Utp14 PF04615.8 ETO04241.1 - 0.76 7.8 30.9 1.1 7.3 21.4 1.2 1 0 0 1 1 1 0 Utp14 protein GOLD_2 PF13897.1 ETO04241.1 - 3.6 7.8 15.8 2.8 8.1 3.4 2.8 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Kelch_4 PF13418.1 ETO04242.1 - 3.4e-15 55.5 1.7 9.9e-09 34.8 0.2 4.0 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO04242.1 - 2.4e-13 49.6 7.7 7.1e-06 25.9 0.2 5.4 3 1 2 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO04242.1 - 1.6e-10 40.3 5.7 4.6e-06 26.0 0.1 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO04242.1 - 1.3e-07 31.0 3.4 0.012 15.3 0.2 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 ETO04242.1 - 8.6e-05 22.5 0.0 2.1 8.6 0.0 4.2 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO04242.1 - 0.00039 20.2 0.0 2.5 8.1 0.0 3.5 3 0 0 3 3 3 2 Kelch motif TLD PF07534.11 ETO04243.1 - 2.6e-11 43.6 0.2 3.9e-11 43.0 0.1 1.3 1 1 0 1 1 1 1 TLD PSCyt3 PF07627.6 ETO04244.1 - 0.023 14.5 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) DUF1583 PF07622.6 ETO04244.1 - 0.2 10.0 1.4 1.1 7.6 1.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1583) DUF3333 PF11812.3 ETO04246.1 - 0.049 13.6 0.1 0.14 12.1 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3333) DEP PF00610.16 ETO04247.1 - 2.7e-17 62.2 0.0 4.7e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF2183 PF09949.4 ETO04247.1 - 0.11 12.5 0.3 0.24 11.3 0.1 1.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2183) START PF01852.14 ETO04249.1 - 4e-14 52.4 1.2 6.6e-12 45.1 0.5 2.9 2 1 1 3 3 3 2 START domain DUF3074 PF11274.3 ETO04249.1 - 0.0012 18.5 0.4 0.0086 15.7 0.3 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF3074) DUF3694 PF12473.3 ETO04249.1 - 0.049 13.2 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Kinesin protein Nucleo_P87 PF07267.6 ETO04249.1 - 0.072 11.7 5.5 0.13 10.9 3.8 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF3702 PF12486.3 ETO04250.1 - 0.079 12.6 0.2 0.34 10.5 0.0 1.8 1 1 1 2 2 2 0 ImpA domain protein Amb_V_allergen PF03913.8 ETO04251.1 - 0.042 13.5 0.2 0.066 12.9 0.1 1.3 1 0 0 1 1 1 0 Amb V Allergen DUF1528 PF07515.6 ETO04252.1 - 0.042 13.8 3.9 1.1 9.2 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1528) Hom_end_hint PF05203.11 ETO04252.1 - 0.085 12.5 3.5 0.11 12.1 2.4 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint Imm32 PF15579.1 ETO04252.1 - 0.1 12.1 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 32 MRL1 PF13003.2 ETO04252.1 - 1.6 8.5 17.8 0.41 10.4 10.0 1.7 2 1 0 2 2 2 0 Ribosomal protein L1 DUF4366 PF14283.1 ETO04254.1 - 0.04 13.3 0.7 0.055 12.8 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) SecA_DEAD PF07517.9 ETO04255.1 - 5.3e-09 35.7 0.0 5.3e-09 35.7 0.0 5.4 6 1 0 6 6 6 1 SecA DEAD-like domain Helicase_C PF00271.26 ETO04255.1 - 0.0046 16.7 0.1 0.048 13.5 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain FUSC-like PF12805.2 ETO04255.1 - 5.6 5.7 11.9 1.7 7.4 2.8 3.4 3 1 1 4 4 4 0 FUSC-like inner membrane protein yccS zf-C2H2 PF00096.21 ETO04256.1 - 9.7e-05 22.4 1.4 0.00036 20.6 1.0 2.1 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETO04256.1 - 0.0045 17.2 0.6 0.0045 17.2 0.4 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 ETO04256.1 - 0.019 15.1 0.2 0.054 13.6 0.1 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 ETO04256.1 - 0.027 14.2 0.9 0.092 12.5 0.6 1.8 1 0 0 1 1 1 0 BED zinc finger zf-FCS PF06467.9 ETO04256.1 - 0.068 12.8 0.3 0.15 11.7 0.2 1.6 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif vWA-TerF-like PF10138.4 ETO04258.1 - 0.038 13.8 0.0 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 vWA found in TerF C terminus FAD_binding_4 PF01565.18 ETO04259.1 - 0.062 12.7 0.0 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain WD40 PF00400.27 ETO04260.1 - 9.2e-20 69.7 9.4 1.3e-09 37.5 0.1 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO04260.1 - 0.0086 14.2 1.9 0.27 9.3 0.0 2.7 2 1 1 3 3 3 2 Nucleoporin Nup120/160 DUF2927 PF11150.3 ETO04262.1 - 0.063 12.9 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2927) DUF2851 PF11013.3 ETO04263.1 - 0.03 13.0 0.1 0.032 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2851) YajC PF02699.10 ETO04264.1 - 0.76 9.4 4.1 2.3 7.9 1.4 2.6 2 0 0 2 2 2 0 Preprotein translocase subunit DOG1 PF14144.1 ETO04265.1 - 0.0053 16.7 0.4 0.0053 16.7 0.3 2.5 3 2 0 3 3 3 1 Seed dormancy control Vpu PF00558.14 ETO04265.1 - 2 8.0 9.8 5.1 6.7 0.8 2.7 2 0 0 2 2 2 0 Vpu protein DUF3349 PF11829.3 ETO04265.1 - 5 7.6 7.6 17 5.8 1.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3349) WD40 PF00400.27 ETO04266.1 - 3.2e-46 153.5 16.2 1.9e-10 40.2 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO04266.1 - 0.0016 16.6 5.5 0.29 9.1 0.1 4.2 2 2 1 4 4 4 2 Nucleoporin Nup120/160 EPTP PF03736.12 ETO04266.1 - 0.021 14.5 0.5 9.5 6.0 0.0 3.4 3 0 0 3 3 3 0 EPTP domain IncA PF04156.9 ETO04266.1 - 0.098 12.2 10.2 0.15 11.6 7.1 1.2 1 0 0 1 1 1 0 IncA protein BING4CT PF08149.6 ETO04266.1 - 0.14 11.7 2.9 1.1 8.8 0.0 3.1 3 0 0 3 3 3 0 BING4CT (NUC141) domain Kelch_6 PF13964.1 ETO04266.1 - 1.1 9.5 5.3 1.6 9.0 0.1 3.7 5 0 0 5 5 5 0 Kelch motif Ole-e-6 PF09253.5 ETO04266.1 - 1.8 8.2 7.4 1 9.0 0.1 3.2 2 1 0 2 2 2 0 Pollen allergen ole e 6 APC_CDC26 PF10471.4 ETO04267.1 - 0.84 10.4 5.4 1.7 9.4 3.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 DUF3634 PF12321.3 ETO04268.1 - 0.068 13.1 0.5 0.11 12.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3634) Toxin_8 PF07365.7 ETO04268.1 - 0.13 12.2 3.3 0.45 10.5 2.3 2.0 1 0 0 1 1 1 0 Alpha conotoxin precursor EZH2_WD-Binding PF11616.3 ETO04269.1 - 0.17 11.7 0.5 0.31 10.9 0.4 1.3 1 0 0 1 1 1 0 WD repeat binding protein EZH2 DEAD PF00270.24 ETO04271.1 - 2.1e-09 37.0 0.3 2.8e-09 36.7 0.2 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-TAZ PF02135.11 ETO04271.1 - 0.007 16.3 1.9 0.015 15.3 1.3 1.5 1 0 0 1 1 1 1 TAZ zinc finger IFT43 PF15305.1 ETO04272.1 - 0.032 14.2 0.5 0.068 13.1 0.3 1.5 1 0 0 1 1 1 0 Intraflagellar transport protein 43 Fcf2 PF08698.6 ETO04272.1 - 0.1 12.6 0.2 0.2 11.7 0.1 1.6 2 0 0 2 2 2 0 Fcf2 pre-rRNA processing API5 PF05918.6 ETO04273.1 - 0.13 10.7 7.3 0.28 9.6 5.1 1.5 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) FYVE_2 PF02318.11 ETO04275.1 - 0.035 13.9 2.6 1.6 8.6 0.1 2.8 3 0 0 3 3 3 0 FYVE-type zinc finger UspB PF10625.4 ETO04275.1 - 0.059 13.1 0.8 2.7 7.8 0.1 2.3 1 1 1 2 2 2 0 Universal stress protein B (UspB) zf-C3HC4_3 PF13920.1 ETO04277.1 - 6.2e-08 32.1 8.5 6.2e-08 32.1 5.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO04277.1 - 0.0062 16.5 9.0 0.018 15.0 6.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 ETO04277.1 - 0.27 10.8 4.2 0.69 9.5 2.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.1 ETO04277.1 - 4.7 7.0 16.0 0.1 12.3 6.2 1.9 2 0 0 2 2 2 0 zinc-RING finger domain Protocadherin PF08374.6 ETO04278.1 - 0.001 18.7 4.2 0.001 18.7 2.9 2.2 1 1 1 2 2 2 1 Protocadherin DUF2535 PF10751.4 ETO04278.1 - 0.074 13.1 2.5 0.13 12.4 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2535) IncA PF04156.9 ETO04278.1 - 0.1 12.1 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 IncA protein Tetraspannin PF00335.15 ETO04278.1 - 0.13 11.4 4.2 0.31 10.2 2.9 1.6 1 1 0 1 1 1 0 Tetraspanin family DUF1183 PF06682.7 ETO04278.1 - 0.38 10.3 9.1 2.7 7.5 4.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1183) DUF106 PF01956.11 ETO04278.1 - 1 8.8 13.9 0.095 12.2 1.5 2.1 1 1 1 2 2 2 0 Integral membrane protein DUF106 Mem_trans PF03547.13 ETO04278.1 - 1.8 6.7 9.6 0.25 9.5 1.7 2.0 1 1 1 2 2 2 0 Membrane transport protein COX16 PF14138.1 ETO04278.1 - 3 8.0 8.0 0.26 11.4 0.6 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Peroxin-13_N PF04088.8 ETO04278.1 - 9.3 6.1 12.6 8.6 6.2 0.8 2.4 1 1 0 2 2 2 0 Peroxin 13, N-terminal region ABC_tran PF00005.22 ETO04279.1 - 0.055 13.7 0.3 0.12 12.7 0.2 1.7 1 1 0 1 1 1 0 ABC transporter PRD PF00874.15 ETO04279.1 - 0.51 10.4 4.5 0.61 10.2 0.8 2.6 3 0 0 3 3 3 0 PRD domain HSP90 PF00183.13 ETO04280.1 - 9.7e-41 139.7 15.9 7.6e-18 64.1 1.7 3.7 1 1 2 3 3 3 3 Hsp90 protein HATPase_c_3 PF13589.1 ETO04280.1 - 0.0021 17.6 0.4 0.1 12.2 0.2 2.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Fasciclin PF02469.17 ETO04280.1 - 0.074 13.0 2.4 0.42 10.6 0.2 2.4 2 0 0 2 2 2 0 Fasciclin domain RST PF12174.3 ETO04280.1 - 0.33 10.7 3.4 0.27 11.0 0.3 2.4 3 0 0 3 3 3 0 RCD1-SRO-TAF4 (RST) plant domain RVT_1 PF00078.22 ETO04281.1 - 0.024 14.0 0.7 0.066 12.5 0.0 2.0 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) PUB PF09409.5 ETO04284.1 - 0.0024 17.5 3.9 0.024 14.3 0.1 3.0 2 1 1 3 3 3 2 PUB domain DUF1890 PF09001.6 ETO04286.1 - 0.032 14.2 0.0 0.045 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1890) CHAT PF12770.2 ETO04287.1 - 0.00013 21.2 0.1 0.00018 20.7 0.0 1.3 1 0 0 1 1 1 1 CHAT domain DUF4550 PF15084.1 ETO04287.1 - 0.0054 16.8 0.5 1.7 8.7 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4550) CoA_binding PF02629.14 ETO04287.1 - 0.093 13.2 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain DUF911 PF06023.7 ETO04289.1 - 0.05 12.8 2.2 0.084 12.0 1.1 1.5 1 1 1 2 2 2 0 Archaeal protein of unknown function (DUF911) Bd3614_N PF14442.1 ETO04291.1 - 0.33 10.9 4.8 0.71 9.8 3.3 1.5 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal PWWP PF00855.12 ETO04292.1 - 0.042 14.0 0.9 0.091 12.9 0.6 1.6 1 0 0 1 1 1 0 PWWP domain RCC1 PF00415.13 ETO04293.1 - 7.6e-42 141.3 11.9 1.6e-12 47.4 0.0 5.7 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO04293.1 - 2.5e-20 71.5 29.9 5.5e-07 29.0 0.3 6.3 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Herpes_U47 PF05467.6 ETO04293.1 - 0.015 13.1 0.7 0.034 12.0 0.5 1.5 1 0 0 1 1 1 0 Herpesvirus glycoprotein U47 Phosphoesterase PF04185.9 ETO04294.1 - 1.8e-54 185.3 1.9 2.4e-54 184.9 1.3 1.2 1 0 0 1 1 1 1 Phosphoesterase family INCENP_ARK-bind PF03941.10 ETO04296.1 - 0.055 13.3 1.8 0.098 12.5 1.2 1.4 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region Toxin_43 PF15604.1 ETO04296.1 - 0.088 12.8 5.0 0.16 12.0 3.5 1.4 1 0 0 1 1 1 0 Putative toxin 43 CBFB_NFYA PF02045.10 ETO04296.1 - 0.11 13.0 1.1 0.11 13.0 0.8 2.5 2 0 0 2 2 2 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B TPR_12 PF13424.1 ETO04297.1 - 8.4e-11 41.6 0.1 1.1e-10 41.3 0.1 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO04297.1 - 2.9e-06 26.6 3.9 0.02 14.4 0.2 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO04297.1 - 3.5e-05 23.3 0.6 0.065 13.1 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO04297.1 - 5.8e-05 22.6 5.7 0.00047 19.7 1.0 1.9 1 1 1 2 2 2 2 TPR repeat Ten1 PF12658.2 ETO04297.1 - 0.00029 20.5 0.0 0.00033 20.3 0.0 1.2 1 0 0 1 1 1 1 Telomere capping, CST complex subunit TPR_7 PF13176.1 ETO04297.1 - 0.0003 20.3 0.0 0.034 13.9 0.0 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETO04297.1 - 0.0018 18.1 0.0 0.004 17.0 0.0 1.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO04297.1 - 0.0018 18.2 1.0 6.1 7.3 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO04297.1 - 0.0097 16.0 2.1 0.023 14.8 0.9 1.8 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 ETO04297.1 - 0.047 13.4 7.0 0.16 11.8 0.3 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat s48_45 PF07422.8 ETO04297.1 - 0.081 13.0 3.2 0.085 12.9 2.2 1.2 1 0 0 1 1 1 0 Sexual stage antigen s48/45 domain PRANC PF09372.5 ETO04297.1 - 1.1 9.2 6.6 1.6 8.7 4.5 1.3 1 1 0 1 1 1 0 PRANC domain Ion_trans PF00520.26 ETO04298.1 - 0.091 11.9 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Ion transport protein Neur_chan_memb PF02932.11 ETO04298.1 - 0.42 10.4 1.7 0.97 9.2 1.2 1.6 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Sporozoite_P67 PF05642.6 ETO04298.1 - 0.64 7.8 4.2 0.7 7.6 2.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.7 ETO04298.1 - 0.9 8.7 7.5 1.1 8.4 5.2 1.2 1 0 0 1 1 1 0 NOA36 protein SR-25 PF10500.4 ETO04299.1 - 7 6.0 9.5 12 5.3 6.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Tmp39 PF10271.4 ETO04300.1 - 0.045 12.4 4.9 0.056 12.1 3.4 1.1 1 0 0 1 1 1 0 Putative transmembrane protein EamA PF00892.15 ETO04300.1 - 0.051 13.6 3.2 0.054 13.5 1.2 1.7 2 0 0 2 2 2 0 EamA-like transporter family CoA_binding_3 PF13727.1 ETO04300.1 - 0.13 12.0 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 CoA-binding domain LRR_1 PF00560.28 ETO04301.1 - 3.3e-06 26.3 18.7 9.5 6.7 0.0 9.2 9 0 0 9 9 9 4 Leucine Rich Repeat LRR_4 PF12799.2 ETO04301.1 - 7.5e-05 22.2 29.6 0.0075 15.8 1.4 5.9 3 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO04301.1 - 0.00025 20.7 10.9 0.001 18.7 1.3 5.7 4 1 3 7 7 7 5 Leucine rich repeat LRR_7 PF13504.1 ETO04301.1 - 2.7 8.5 15.1 69 4.3 0.1 6.8 6 0 0 6 6 6 0 Leucine rich repeat WD40 PF00400.27 ETO04304.1 - 3.6e-24 83.6 7.1 3.3e-11 42.6 0.1 4.2 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO04304.1 - 4.1e-05 21.9 0.3 0.21 9.6 0.1 2.8 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO04304.1 - 0.029 13.1 1.0 1.8 7.2 0.0 2.5 1 1 1 2 2 2 0 Nup133 N terminal like PPPI_inhib PF14895.1 ETO04305.1 - 0.041 12.6 0.9 0.059 12.0 0.6 1.3 1 0 0 1 1 1 0 Protein phosphatase 1 inhibitor SR-25 PF10500.4 ETO04306.1 - 0.0024 17.3 10.9 0.004 16.6 7.6 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Gal4_dimer PF03902.8 ETO04306.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Gal4-like dimerisation domain CAF-1_p150 PF11600.3 ETO04306.1 - 2.2 7.6 10.3 4.6 6.5 7.1 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2146 PF10220.4 ETO04306.1 - 8.9 4.1 9.5 0.38 8.6 2.8 1.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2146) Spo12 PF05032.7 ETO04309.1 - 0.057 13.0 0.2 0.057 13.0 0.1 1.9 2 0 0 2 2 2 0 Spo12 family N6_N4_Mtase PF01555.13 ETO04309.1 - 0.069 12.6 0.5 0.089 12.2 0.3 1.1 1 0 0 1 1 1 0 DNA methylase DUF1462 PF07315.6 ETO04310.1 - 0.025 14.5 0.3 0.14 12.1 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1462) DUF2115 PF09888.4 ETO04310.1 - 0.031 14.3 0.4 0.037 14.1 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) RRM_1 PF00076.17 ETO04312.1 - 7.1e-18 64.0 0.1 2e-17 62.5 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO04312.1 - 4e-15 55.5 0.0 1.1e-14 54.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO04312.1 - 3e-09 36.5 0.0 5.9e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AIG1 PF04548.11 ETO04314.1 - 2.8e-14 52.7 0.6 4.5e-14 52.0 0.0 1.6 2 0 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.18 ETO04314.1 - 8.6e-06 25.6 0.0 2.2e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 ETO04314.1 - 0.0041 17.1 0.2 0.066 13.1 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain KaiC PF06745.8 ETO04314.1 - 0.0073 15.4 1.2 0.028 13.5 0.0 2.4 2 1 0 2 2 2 1 KaiC RNA_helicase PF00910.17 ETO04314.1 - 0.0093 16.1 0.0 0.036 14.2 0.0 2.1 1 1 0 1 1 1 1 RNA helicase AAA_22 PF13401.1 ETO04314.1 - 0.013 15.6 0.1 0.076 13.1 0.0 2.5 1 1 1 2 2 2 0 AAA domain DEAD PF00270.24 ETO04314.1 - 0.037 13.5 0.0 11 5.4 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase Methyltransf_14 PF08484.6 ETO04314.1 - 0.038 13.5 0.6 0.069 12.6 0.1 1.6 2 0 0 2 2 2 0 C-methyltransferase C-terminal domain Arch_ATPase PF01637.13 ETO04314.1 - 0.043 13.5 0.0 0.043 13.5 0.0 2.3 1 1 1 2 2 2 0 Archaeal ATPase Sigma54_activat PF00158.21 ETO04314.1 - 0.05 13.0 0.0 0.098 12.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 ETO04314.1 - 0.081 13.2 2.8 0.27 11.5 0.0 2.3 1 1 1 2 2 2 0 ABC transporter Neur_chan_memb PF02932.11 ETO04314.1 - 0.1 12.4 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AAA PF00004.24 ETO04314.1 - 0.1 12.7 0.9 2.5 8.3 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Tom37_C PF11801.3 ETO04314.1 - 0.46 10.3 4.5 0.89 9.3 3.1 1.5 1 0 0 1 1 1 0 Tom37 C-terminal domain AAA_23 PF13476.1 ETO04314.1 - 1.1 9.5 8.5 29 4.8 5.1 2.2 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 ETO04314.1 - 1.2 8.9 4.8 6.3 6.5 3.3 2.6 1 1 0 1 1 1 0 Dynamin family WD40 PF00400.27 ETO04315.1 - 2.6e-48 160.2 18.4 1.4e-10 40.6 0.1 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO04315.1 - 1.5e-08 33.2 2.1 0.00027 19.2 0.1 3.9 2 1 1 3 3 3 3 Nucleoporin Nup120/160 TAFA PF12020.3 ETO04316.1 - 0.014 15.5 0.4 0.039 14.0 0.1 1.8 1 1 1 2 2 2 0 TAFA family DUF3295 PF11702.3 ETO04316.1 - 0.062 12.2 3.8 0.071 12.0 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) FCP1_C PF09309.5 ETO04317.1 - 0.022 14.0 5.8 0.027 13.7 4.1 1.1 1 0 0 1 1 1 0 FCP1, C-terminal DUF912 PF06024.7 ETO04317.1 - 0.15 12.1 1.0 0.22 11.5 0.7 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) OATP PF03137.15 ETO04317.1 - 0.17 9.8 0.2 0.2 9.6 0.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family FimP PF09766.4 ETO04317.1 - 0.3 10.1 8.2 0.35 9.8 5.7 1.1 1 0 0 1 1 1 0 Fms-interacting protein CDC45 PF02724.9 ETO04317.1 - 0.99 7.3 6.9 1.1 7.2 4.8 1.0 1 0 0 1 1 1 0 CDC45-like protein ERF PF04404.7 ETO04317.1 - 0.99 8.9 10.3 1.5 8.3 7.1 1.2 1 0 0 1 1 1 0 ERF superfamily Pex16 PF08610.5 ETO04317.1 - 1.7 7.5 4.2 2.3 7.1 2.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) WD40 PF00400.27 ETO04318.1 - 1.2e-84 275.4 24.2 1.3e-13 50.2 0.1 7.5 8 0 0 8 8 8 7 WD domain, G-beta repeat PD40 PF07676.7 ETO04318.1 - 6.6e-06 25.6 8.4 9.4 6.0 0.0 6.2 6 0 0 6 6 6 3 WD40-like Beta Propeller Repeat Pentapeptide_4 PF13599.1 ETO04318.1 - 1.5e-05 24.6 3.0 6.6e-05 22.6 2.1 2.1 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 ETO04318.1 - 3.3e-05 23.6 6.5 0.00063 19.5 1.8 3.3 2 1 2 4 4 4 3 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETO04318.1 - 5.5e-05 22.3 2.4 0.0025 17.0 0.1 2.9 2 1 1 3 3 3 2 Pentapeptide repeats (8 copies) DUF3732 PF12532.3 ETO04318.1 - 0.0011 18.5 0.6 21 4.5 0.0 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF3732) DUF1258 PF06869.7 ETO04318.1 - 0.0032 16.5 5.7 2.3 7.2 0.1 3.8 2 1 1 4 4 4 2 Protein of unknown function (DUF1258) 3-dmu-9_3-mt PF06983.8 ETO04318.1 - 0.02 15.2 0.7 0.66 10.3 0.1 3.0 1 1 0 2 2 2 0 3-demethylubiquinone-9 3-methyltransferase USP7_C2 PF14533.1 ETO04318.1 - 0.03 13.7 0.0 3.9 6.8 0.0 3.4 3 2 1 4 4 4 0 Ubiquitin-specific protease C-terminal ArfGap PF01412.13 ETO04320.1 - 4.1e-28 97.5 0.1 4.1e-28 97.5 0.1 2.2 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf Glyco_transf_8C PF08437.5 ETO04320.1 - 0.24 11.4 1.6 0.45 10.5 0.2 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 8 C-terminal FMO-like PF00743.14 ETO04321.1 - 2.2e-05 22.8 0.0 2.8e-05 22.5 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like ADK PF00406.17 ETO04322.1 - 3.8e-09 36.5 0.0 4.5e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_33 PF13671.1 ETO04322.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Daxx PF03344.10 ETO04323.1 - 0.11 10.9 10.8 0.12 10.8 7.5 1.0 1 0 0 1 1 1 0 Daxx Family FGF-BP1 PF06473.7 ETO04323.1 - 0.17 11.4 4.0 0.2 11.2 2.8 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) GLF PF03275.8 ETO04323.1 - 0.52 9.7 2.8 4 6.9 0.3 2.0 2 0 0 2 2 2 0 UDP-galactopyranose mutase DUF4637 PF15470.1 ETO04323.1 - 0.78 9.3 3.5 1 8.9 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Ycf1 PF05758.7 ETO04323.1 - 1.3 6.6 6.8 1.3 6.6 4.7 1.0 1 0 0 1 1 1 0 Ycf1 CDC45 PF02724.9 ETO04323.1 - 3.8 5.4 8.6 4.1 5.3 6.0 1.0 1 0 0 1 1 1 0 CDC45-like protein RRM_1 PF00076.17 ETO04324.1 - 2.5e-14 52.6 0.8 4.8e-07 29.3 0.2 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO04324.1 - 1.3e-09 37.9 0.1 0.00056 19.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO04324.1 - 4.2e-05 23.2 0.6 0.012 15.4 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1298 PF06974.8 ETO04325.1 - 0.0017 18.1 0.0 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) Condensation PF00668.15 ETO04325.1 - 0.0061 15.4 0.1 0.02 13.7 0.0 1.7 2 0 0 2 2 2 1 Condensation domain WES_acyltransf PF03007.11 ETO04325.1 - 0.033 13.7 0.1 0.39 10.2 0.0 2.5 1 1 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF911 PF06023.7 ETO04326.1 - 0.0034 16.6 1.7 0.0039 16.4 1.1 1.0 1 0 0 1 1 1 1 Archaeal protein of unknown function (DUF911) DUF4202 PF13875.1 ETO04326.1 - 0.029 14.0 0.2 0.035 13.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4202) ERp29 PF07749.7 ETO04326.1 - 0.073 13.7 1.7 0.12 13.0 1.2 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain DUF1670 PF07900.6 ETO04326.1 - 0.13 11.4 4.0 0.14 11.3 1.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1670) Kazal_1 PF00050.16 ETO04326.1 - 0.14 12.1 0.1 0.31 11.0 0.0 1.8 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain WD40 PF00400.27 ETO04327.1 - 5.2e-54 178.3 15.7 1.4e-11 43.8 0.1 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO04327.1 - 1.6e-10 39.7 8.4 0.00065 17.9 0.3 4.8 1 1 3 5 5 5 5 Nucleoporin Nup120/160 TRAM_LAG1_CLN8 PF03798.11 ETO04327.1 - 0.23 10.9 3.0 0.33 10.4 2.1 1.2 1 0 0 1 1 1 0 TLC domain UPF0020 PF01170.13 ETO04329.1 - 7.8e-18 64.6 0.0 1.2e-15 57.5 0.0 2.4 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 ETO04329.1 - 1.5e-05 25.0 0.0 0.00015 21.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETO04329.1 - 0.00016 21.1 0.0 0.006 15.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain THUMP PF02926.12 ETO04329.1 - 0.001 18.9 0.1 0.0045 16.8 0.0 2.1 2 0 0 2 2 2 1 THUMP domain N6_Mtase PF02384.11 ETO04329.1 - 0.0011 18.0 0.2 0.0065 15.5 0.0 2.2 1 1 1 2 2 2 1 N-6 DNA Methylase Methyltransf_31 PF13847.1 ETO04329.1 - 0.0015 18.1 0.0 0.04 13.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain N6-adenineMlase PF10237.4 ETO04329.1 - 0.0072 16.0 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase DUF912 PF06024.7 ETO04329.1 - 0.049 13.6 0.3 0.17 11.9 0.2 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Myotub-related PF06602.9 ETO04330.1 - 2.8e-71 240.1 1.3 3.8e-71 239.7 0.9 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain FYVE PF01363.16 ETO04330.1 - 3.7e-14 52.3 9.6 9e-14 51.1 6.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 ETO04330.1 - 4.6e-05 23.2 5.9 0.00011 22.0 4.1 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger Orbi_NS3 PF01616.11 ETO04330.1 - 0.076 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Orbivirus NS3 Y_phosphatase3 PF13350.1 ETO04330.1 - 0.077 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF4637 PF15470.1 ETO04330.1 - 0.22 11.1 1.8 0.5 9.9 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) zf-B_box PF00643.19 ETO04330.1 - 7.6 6.5 15.5 4 7.4 6.8 2.8 2 1 0 2 2 2 0 B-box zinc finger DUF2701 PF10857.3 ETO04333.1 - 0.71 9.6 4.7 0.5 10.1 1.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2701) Beta_propel PF09826.4 ETO04334.1 - 0.021 13.1 0.8 0.026 12.8 0.3 1.3 1 1 0 1 1 1 0 Beta propeller domain ClpB_D2-small PF10431.4 ETO04335.1 - 4.2e-06 26.5 0.5 8.8e-06 25.5 0.2 1.7 2 1 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein Pkinase PF00069.20 ETO04336.1 - 5.2e-57 192.9 0.0 9.5e-57 192.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO04336.1 - 3.3e-22 78.8 0.0 1.1e-21 77.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO04336.1 - 0.0077 15.2 0.0 0.021 13.7 0.0 1.9 1 1 0 1 1 1 1 Kinase-like DUF515 PF04415.7 ETO04337.1 - 0.024 12.9 0.6 0.03 12.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF411 PF04214.8 ETO04337.1 - 0.058 12.9 0.2 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF Pkinase PF00069.20 ETO04338.1 - 2.7e-11 43.1 0.1 3.8e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO04338.1 - 0.028 13.4 0.0 0.034 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Daxx PF03344.10 ETO04338.1 - 0.6 8.5 6.4 0.61 8.5 4.4 1.1 1 0 0 1 1 1 0 Daxx Family Tcp11 PF05794.8 ETO04339.1 - 0.025 13.3 11.4 0.032 12.9 7.9 1.2 1 0 0 1 1 1 0 T-complex protein 11 DUF4128 PF13554.1 ETO04339.1 - 0.053 13.1 2.7 0.069 12.8 0.2 2.2 2 0 0 2 2 2 0 Bacteriophage related domain of unknown function DUF3657 PF12394.3 ETO04339.1 - 0.13 12.3 0.9 0.29 11.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3657) WD40 PF00400.27 ETO04340.1 - 6.3e-34 114.6 16.9 5.9e-12 44.9 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO04340.1 - 4e-09 35.1 2.3 0.0026 15.9 0.2 3.1 1 1 1 3 3 3 3 Nucleoporin Nup120/160 DAOA PF15199.1 ETO04340.1 - 0.32 11.6 2.5 7.1 7.3 0.1 2.5 1 1 1 2 2 2 0 D-amino acid oxidase activator WD40 PF00400.27 ETO04341.1 - 7.9e-22 76.2 6.8 4.3e-11 42.2 1.4 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO04341.1 - 7.8e-05 20.9 1.6 0.0021 16.2 0.1 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 WD40 PF00400.27 ETO04342.1 - 6.2e-20 70.2 0.9 1.2e-10 40.8 0.0 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat Ricin_B_lectin PF00652.17 ETO04342.1 - 0.016 15.2 1.3 0.03 14.3 0.9 1.5 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain Nup160 PF11715.3 ETO04342.1 - 0.026 12.6 0.3 0.28 9.2 0.2 2.0 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Ribosomal_S5_C PF03719.10 ETO04343.1 - 9.8e-24 82.4 0.1 1.5e-23 81.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 ETO04343.1 - 1.3e-23 82.5 0.3 2.7e-23 81.4 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DUF1091 PF06477.8 ETO04344.1 - 0.033 14.6 0.4 0.1 13.0 0.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1091) Pentapeptide_4 PF13599.1 ETO04344.1 - 0.96 9.2 7.0 29 4.5 2.4 4.4 2 1 2 4 4 4 0 Pentapeptide repeats (9 copies) WD40 PF00400.27 ETO04346.1 - 3.1e-38 128.2 14.7 4.9e-11 42.0 1.7 5.1 5 1 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO04346.1 - 1.8e-07 29.7 0.3 0.19 9.8 0.0 3.9 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO04346.1 - 0.097 11.4 12.4 1.7 7.3 0.3 4.0 1 1 3 4 4 4 0 Nup133 N terminal like WD40 PF00400.27 ETO04347.1 - 2.6e-37 125.3 25.6 3.9e-10 39.2 0.1 8.0 7 1 1 8 8 8 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO04347.1 - 8.2e-08 30.8 4.7 0.3 9.1 0.0 4.5 2 1 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO04347.1 - 0.00018 20.4 6.3 0.21 10.2 0.1 3.5 1 1 1 3 3 3 3 Nup133 N terminal like CAAP1 PF15335.1 ETO04348.1 - 0.016 15.3 0.7 2.7 8.2 0.3 2.6 3 0 0 3 3 3 0 Caspase activity and apoptosis inhibitor 1 WD40 PF00400.27 ETO04349.1 - 6.7e-61 200.1 11.7 9.7e-13 47.4 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO04349.1 - 2.9e-08 32.3 3.5 0.014 13.5 0.0 4.3 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO04349.1 - 3.3e-07 29.4 3.3 0.11 11.1 0.1 3.9 1 1 3 4 4 4 3 Nup133 N terminal like Hira PF07569.6 ETO04349.1 - 8.9e-05 21.8 0.7 9.3 5.4 0.0 4.5 3 2 1 4 4 4 2 TUP1-like enhancer of split PQQ_2 PF13360.1 ETO04349.1 - 0.00011 21.7 0.1 0.0014 18.1 0.1 2.4 1 1 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO04349.1 - 0.0025 16.1 0.1 0.27 9.5 0.0 2.4 1 1 2 3 3 3 2 Cytochrome D1 heme domain DPPIV_N PF00930.16 ETO04349.1 - 0.0029 16.2 0.1 0.55 8.7 0.0 3.3 1 1 3 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF1258 PF06869.7 ETO04349.1 - 0.0053 15.8 1.2 14 4.7 0.1 3.1 2 1 1 3 3 3 1 Protein of unknown function (DUF1258) Nop10p PF04135.7 ETO04349.1 - 0.052 13.2 0.4 4.2 7.1 0.0 2.7 3 0 0 3 3 3 0 Nucleolar RNA-binding protein, Nop10p family PD40 PF07676.7 ETO04349.1 - 0.099 12.3 8.7 15 5.4 0.0 5.5 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat RabGAP-TBC PF00566.13 ETO04350.1 - 1.6e-08 34.2 1.9 2e-08 33.9 1.3 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain U-box PF04564.10 ETO04351.1 - 1.1e-10 41.2 0.0 3.6e-10 39.6 0.0 2.0 1 0 0 1 1 1 1 U-box domain ODV-E18 PF10717.4 ETO04351.1 - 0.12 11.8 2.2 0.25 10.7 1.5 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF763 PF05559.6 ETO04352.1 - 0.03 13.2 0.9 0.032 13.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Tox-SGS PF15651.1 ETO04352.1 - 0.066 13.0 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 Salivary glad secreted protein domain toxin BBP1_N PF15271.1 ETO04352.1 - 0.3 11.4 1.6 0.44 10.9 1.1 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein HSA PF07529.8 ETO04352.1 - 2.5 7.9 8.9 0.21 11.3 2.1 2.1 2 0 0 2 2 2 0 HSA DUF342 PF03961.8 ETO04352.1 - 6.7 5.0 6.7 8.1 4.7 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APC_CDC26 PF10471.4 ETO04353.1 - 0.074 13.8 4.6 0.092 13.4 3.2 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Selenoprotein_S PF06936.6 ETO04353.1 - 0.12 11.9 4.0 0.14 11.6 2.8 1.0 1 0 0 1 1 1 0 Selenoprotein S (SelS) Apis_Csd PF11671.3 ETO04353.1 - 0.58 9.9 6.5 0.65 9.7 4.5 1.1 1 0 0 1 1 1 0 Complementary sex determiner protein U1snRNP70_N PF12220.3 ETO04353.1 - 7.5 6.9 8.7 0.56 10.5 2.6 1.6 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal WD40 PF00400.27 ETO04354.1 - 9.3e-55 180.6 17.9 1.7e-12 46.7 0.0 5.5 5 1 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO04354.1 - 9.7e-14 50.4 2.8 2.4e-05 22.6 0.1 4.8 1 1 4 5 5 5 5 Nucleoporin Nup120/160 ClpB_D2-small PF10431.4 ETO04355.1 - 0.14 12.0 0.8 0.9 9.4 0.0 2.2 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein Haemolytic PF01809.13 ETO04356.1 - 0.047 13.3 0.0 0.088 12.4 0.0 1.4 1 0 0 1 1 1 0 Haemolytic domain WD40 PF00400.27 ETO04357.1 - 4.1e-45 150.1 24.0 7.1e-12 44.7 0.1 8.1 6 2 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO04357.1 - 4.7e-09 34.9 2.4 0.017 13.2 0.6 4.7 2 1 2 4 4 4 4 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO04357.1 - 0.00077 18.8 1.7 0.14 11.4 0.1 3.0 1 1 2 3 3 3 2 Domain of unknown function (DUF4221) DUF3601 PF12208.3 ETO04357.1 - 0.033 14.1 0.1 9.2 6.2 0.0 3.6 2 1 1 4 4 4 0 Domain of unknown function (DUF3601) DUF851 PF05867.6 ETO04357.1 - 0.087 12.0 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF851) HAD PF12710.2 ETO04357.1 - 0.44 10.6 2.3 29 4.7 0.0 3.1 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase WD40 PF00400.27 ETO04358.1 - 4.3e-61 200.7 24.8 1e-10 41.0 0.0 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO04358.1 - 1.5e-08 33.2 3.4 0.09 10.9 0.1 4.8 2 2 1 4 4 4 4 Nucleoporin Nup120/160 DUF1574 PF07611.6 ETO04359.1 - 0.0015 17.4 1.5 0.0017 17.2 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1574) PPR_2 PF13041.1 ETO04360.1 - 1.3e-13 50.7 6.5 8e-06 25.7 1.0 4.8 5 0 0 5 5 5 3 PPR repeat family PPR PF01535.15 ETO04360.1 - 9e-11 41.0 5.5 0.015 15.2 0.0 4.6 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.1 ETO04360.1 - 1.9e-10 40.1 0.0 0.035 14.4 0.1 5.1 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 ETO04360.1 - 2.6e-05 23.6 1.1 0.69 9.4 0.0 3.8 3 0 0 3 3 3 2 PPR repeat Dehydratase_SU PF02287.10 ETO04360.1 - 0.015 15.0 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 Dehydratase small subunit WD40 PF00400.27 ETO04361.1 - 5.9e-36 121.0 11.1 5.1e-13 48.3 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO04361.1 - 6.4e-09 34.4 2.6 0.0045 15.1 0.4 3.2 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Geminin PF07412.7 ETO04361.1 - 0.011 15.4 17.4 0.11 12.1 5.7 2.6 1 1 1 2 2 2 0 Geminin Atg14 PF10186.4 ETO04361.1 - 0.051 12.5 7.4 0.07 12.0 5.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF869 PF05911.6 ETO04361.1 - 0.21 9.7 13.2 0.3 9.2 9.2 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Orbi_VP5 PF00901.12 ETO04361.1 - 0.36 8.9 7.9 0.55 8.3 5.5 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 She9_MDM33 PF05546.6 ETO04361.1 - 0.46 9.9 11.4 1.7 8.1 7.9 1.8 1 1 0 1 1 1 0 She9 / Mdm33 family DUF3682 PF12446.3 ETO04361.1 - 0.55 10.5 5.5 0.87 9.8 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) FCP1_C PF09309.5 ETO04361.1 - 5.8 6.1 7.7 8.8 5.5 5.3 1.2 1 0 0 1 1 1 0 FCP1, C-terminal Kelch_6 PF13964.1 ETO04362.1 - 2.1e-05 24.4 6.6 0.036 14.2 0.1 4.3 4 1 1 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO04362.1 - 4.5e-05 23.1 1.1 0.16 11.7 0.0 3.6 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO04362.1 - 5.5e-05 23.0 3.1 4.2 7.4 0.6 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO04362.1 - 0.00026 20.6 3.7 0.072 12.8 0.2 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO04362.1 - 0.0023 17.4 6.5 0.1 12.1 0.3 3.5 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO04362.1 - 0.055 13.6 0.3 1.7 8.9 0.0 3.5 4 0 0 4 4 4 0 Galactose oxidase, central domain TPR_12 PF13424.1 ETO04363.1 - 8.8e-18 64.0 0.1 2e-17 62.8 0.1 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETO04363.1 - 2.6e-10 39.8 0.0 6e-07 29.1 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO04363.1 - 4.8e-09 35.7 0.7 7.6e-09 35.1 0.5 1.3 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 ETO04363.1 - 2.7e-08 33.0 2.7 0.0023 17.7 0.3 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO04363.1 - 5.2e-08 32.1 7.9 0.0014 18.1 0.8 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO04363.1 - 8.9e-06 25.5 0.3 0.064 13.4 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO04363.1 - 4.1e-05 23.0 0.1 0.0054 16.4 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO04363.1 - 4.7e-05 22.8 8.4 0.017 14.8 0.8 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat PPR PF01535.15 ETO04363.1 - 0.0029 17.4 1.1 0.012 15.5 0.1 2.3 2 0 0 2 2 2 1 PPR repeat SNAP PF14938.1 ETO04363.1 - 0.0072 15.5 0.1 0.0099 15.0 0.1 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP Apc3 PF12895.2 ETO04363.1 - 0.036 14.2 3.0 0.1 12.7 0.9 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF627 PF04781.7 ETO04363.1 - 0.23 11.0 1.7 4.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF627) Cohesin_load PF10345.4 ETO04363.1 - 0.46 8.6 6.7 0.07 11.3 1.9 1.6 2 0 0 2 2 2 0 Cohesin loading factor TnpV PF14198.1 ETO04364.1 - 0.65 9.9 3.4 8.5 6.3 1.4 2.0 1 1 1 2 2 2 0 Transposon-encoded protein TnpV PPR_2 PF13041.1 ETO04365.1 - 3.4e-19 68.5 6.7 7e-11 41.9 0.3 4.7 3 1 2 5 5 5 5 PPR repeat family PPR PF01535.15 ETO04365.1 - 6.7e-17 60.2 6.4 4.8e-05 23.0 0.0 5.2 5 0 0 5 5 5 4 PPR repeat PPR_3 PF13812.1 ETO04365.1 - 7.6e-15 53.8 0.0 3.7e-05 23.6 0.0 5.2 5 0 0 5 5 5 3 Pentatricopeptide repeat domain PPR_1 PF12854.2 ETO04365.1 - 5.2e-09 35.4 6.1 0.0011 18.4 0.0 4.8 5 0 0 5 5 5 2 PPR repeat DUF3636 PF12331.3 ETO04365.1 - 0.04 13.4 0.6 0.13 11.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3636) HSP70 PF00012.15 ETO04366.1 - 1.9e-48 164.8 0.9 8.7e-33 113.0 0.9 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 ETO04366.1 - 3.5e-10 39.0 0.8 5e-10 38.4 0.5 1.3 1 1 0 1 1 1 1 MreB/Mbl protein MRG PF05712.8 ETO04366.1 - 0.033 13.0 0.1 0.078 11.8 0.1 1.5 1 1 0 1 1 1 0 MRG HSP70 PF00012.15 ETO04367.1 - 2.2e-08 32.4 0.0 3.5e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Hsp70 protein Glyco_hydro_8 PF01270.12 ETO04367.1 - 0.024 13.3 0.0 0.04 12.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 8 WD40 PF00400.27 ETO04371.1 - 3.3e-69 226.5 24.3 5.6e-13 48.2 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO04371.1 - 3.7e-11 41.8 12.4 0.00086 17.5 0.6 5.8 1 1 5 6 6 6 5 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO04371.1 - 0.0038 16.9 3.4 1.9 8.2 0.0 4.8 2 1 3 5 5 5 1 Ciliary BBSome complex subunit 2, middle region V-ATPase_G PF03179.10 ETO04371.1 - 0.44 10.8 7.9 1.3 9.3 5.5 1.8 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF2317 PF10079.4 ETO04371.1 - 1.9 7.0 9.2 2.6 6.5 6.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) WD40 PF00400.27 ETO04373.1 - 9.1e-28 95.1 12.5 5.7e-11 41.8 0.3 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO04373.1 - 0.00079 17.6 0.2 0.5 8.4 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO04373.1 - 0.08 12.7 1.5 4.5 7.0 0.2 3.1 1 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region DUF1921 PF09081.5 ETO04373.1 - 2.6 8.0 5.3 47 4.0 0.1 3.7 3 1 0 4 4 4 0 Domain of unknown function (DUF1921) DUF4619 PF15398.1 ETO04374.1 - 0.0089 15.4 2.6 0.01 15.3 1.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4619) Pox_Ag35 PF03286.9 ETO04374.1 - 0.072 12.6 4.5 0.081 12.4 3.1 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Peptidase_C37 PF05416.7 ETO04374.1 - 0.11 10.7 0.5 0.13 10.5 0.3 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase DUF3584 PF12128.3 ETO04377.1 - 0.0012 16.3 20.1 0.0021 15.5 13.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF3505 PF12013.3 ETO04377.1 - 0.74 10.0 6.4 0.19 11.9 0.8 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3505) DUF2779 PF11074.3 ETO04377.1 - 0.91 9.5 16.0 1.9 8.5 5.8 3.3 1 1 1 2 2 2 0 Domain of unknown function(DUF2779) Vac_Fusion PF02346.11 ETO04377.1 - 1.1 8.7 6.0 16 5.0 0.5 3.2 2 0 0 2 2 2 0 Chordopoxvirus fusion protein DUF190 PF02641.10 ETO04377.1 - 1.2 9.0 6.5 0.23 11.3 0.8 2.6 2 1 2 4 4 4 0 Uncharacterized ACR, COG1993 KIP1 PF07765.7 ETO04377.1 - 1.4 8.8 5.7 14 5.6 0.0 3.2 2 1 1 3 3 3 0 KIP1-like protein Peptidase_S28 PF05577.7 ETO04378.1 - 9.7e-49 166.1 7.2 4.2e-28 98.1 0.2 2.4 2 1 0 2 2 2 2 Serine carboxypeptidase S28 ApoC-I PF04691.7 ETO04379.1 - 0.015 15.0 4.3 0.57 9.9 3.0 2.9 1 1 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) DUF2400 PF09674.5 ETO04379.1 - 0.2 11.3 8.1 0.076 12.7 2.3 2.3 1 1 1 3 3 3 0 Protein of unknown function (DUF2400) NPV_P10 PF05531.7 ETO04379.1 - 0.3 11.3 6.1 15 5.8 4.2 2.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Casein PF00363.13 ETO04379.1 - 0.86 10.2 6.4 0.43 11.2 1.0 2.5 2 0 0 2 2 2 0 Casein BLOC1_2 PF10046.4 ETO04379.1 - 1.9 8.6 20.5 0.21 11.7 1.2 4.1 3 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MitMem_reg PF13012.1 ETO04379.1 - 3.1 7.9 13.1 1.2 9.2 2.5 3.3 1 1 2 3 3 3 0 Maintenance of mitochondrial structure and function DUF948 PF06103.6 ETO04379.1 - 4.6 7.1 12.9 0.26 11.1 1.9 3.1 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF3573 PF12097.3 ETO04379.1 - 6.9 5.1 7.0 10 4.6 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) RRM_1 PF00076.17 ETO04381.1 - 0.042 13.4 0.0 0.2 11.3 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Suppressor_P21 PF11479.3 ETO04381.1 - 0.046 13.4 0.7 3.3 7.4 0.1 2.4 2 0 0 2 2 2 0 RNA silencing suppressor P21 SRI PF08236.6 ETO04383.1 - 0.00093 19.0 0.2 0.0016 18.3 0.1 1.5 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain GerPC PF10737.4 ETO04383.1 - 0.066 12.9 1.0 0.098 12.4 0.7 1.3 1 1 0 1 1 1 0 Spore germination protein GerPC WD40 PF00400.27 ETO04385.1 - 3.9e-58 191.4 20.4 2.9e-10 39.6 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO04385.1 - 1e-11 43.6 1.9 0.061 11.4 0.0 5.4 1 1 4 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO04385.1 - 1.6e-07 30.4 8.8 0.017 13.9 0.3 4.6 1 1 2 5 5 5 4 Nup133 N terminal like WD40 PF00400.27 ETO04386.1 - 2.4e-18 65.2 5.3 4.6e-09 35.8 0.3 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO04386.1 - 2e-08 32.8 4.2 4.6e-06 25.0 0.7 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO04386.1 - 0.011 14.4 0.4 0.3 9.7 0.3 2.1 1 1 1 2 2 2 0 Nup133 N terminal like Methyltransf_12 PF08242.7 ETO04387.1 - 0.075 13.5 2.5 0.23 11.9 1.7 1.8 1 0 0 1 1 1 0 Methyltransferase domain DUF3439 PF11921.3 ETO04387.1 - 0.77 9.5 8.3 1.9 8.2 5.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Apis_Csd PF11671.3 ETO04387.1 - 1.5 8.5 7.8 2.3 8.0 4.0 2.1 2 0 0 2 2 2 0 Complementary sex determiner protein WD40 PF00400.27 ETO04388.1 - 0.001 18.8 0.7 0.0038 17.0 0.1 2.1 2 0 0 2 2 2 1 WD domain, G-beta repeat zf-TRAF PF02176.13 ETO04388.1 - 0.0029 17.9 1.1 0.0029 17.9 0.7 3.0 3 0 0 3 3 3 1 TRAF-type zinc finger TFIIF_alpha PF05793.7 ETO04389.1 - 0.0005 18.5 13.3 0.0005 18.5 9.2 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) YL1 PF05764.8 ETO04389.1 - 0.012 15.2 14.2 0.013 15.1 9.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Arteri_nucleo PF01481.11 ETO04389.1 - 0.013 15.5 0.3 0.021 14.8 0.2 1.3 1 0 0 1 1 1 0 Arterivirus nucleocapsid protein Sigma70_ner PF04546.8 ETO04389.1 - 0.042 13.4 11.6 0.044 13.3 8.0 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.4 ETO04389.1 - 0.048 12.3 18.9 0.046 12.4 13.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 ETO04389.1 - 0.063 11.2 14.9 0.067 11.1 10.3 1.1 1 0 0 1 1 1 0 Nop14-like family Utp14 PF04615.8 ETO04389.1 - 0.091 10.9 14.3 0.088 10.9 9.9 1.0 1 0 0 1 1 1 0 Utp14 protein NST1 PF13945.1 ETO04389.1 - 0.096 12.7 5.0 0.12 12.4 3.5 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator Nop53 PF07767.6 ETO04389.1 - 0.11 11.4 12.3 0.12 11.3 8.5 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PBP1_TM PF14812.1 ETO04389.1 - 0.12 12.7 21.2 0.22 11.8 14.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Daxx PF03344.10 ETO04389.1 - 0.23 9.9 12.4 0.22 9.9 8.6 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 ETO04389.1 - 0.24 9.3 13.4 0.22 9.4 9.3 1.1 1 0 0 1 1 1 0 CDC45-like protein HSP90 PF00183.13 ETO04389.1 - 0.57 8.5 13.1 0.54 8.5 9.1 1.1 1 0 0 1 1 1 0 Hsp90 protein eIF-3c_N PF05470.7 ETO04389.1 - 0.63 8.0 10.4 0.63 8.0 7.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Hep_59 PF07052.6 ETO04389.1 - 1.3 9.3 9.2 1.3 9.4 5.9 1.4 1 1 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 SDA1 PF05285.7 ETO04389.1 - 1.6 7.9 18.7 1.9 7.6 13.0 1.1 1 0 0 1 1 1 0 SDA1 Pox_RNA_Pol_19 PF05320.7 ETO04389.1 - 4.6 6.9 11.9 5.5 6.7 8.2 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF1510 PF07423.6 ETO04389.1 - 5.6 6.2 14.9 6.1 6.1 10.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Sporozoite_P67 PF05642.6 ETO04389.1 - 5.7 4.6 11.0 6 4.5 7.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nucleoplasmin PF03066.10 ETO04389.1 - 7.2 6.1 21.0 13 5.2 14.5 1.5 1 0 0 1 1 1 0 Nucleoplasmin WBS_methylT PF12589.3 ETO04389.1 - 8.8 6.8 11.2 4.9 7.7 6.4 1.6 2 0 0 2 2 1 0 Methyltransferase involved in Williams-Beuren syndrome Mucin PF01456.12 ETO04390.1 - 1 9.1 13.7 2.6 7.8 9.5 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2207 PF09972.4 ETO04391.1 - 0.34 9.4 6.5 0.4 9.1 4.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) WD40 PF00400.27 ETO04395.1 - 9.6e-57 186.9 25.1 7.7e-11 41.4 0.4 7.2 6 1 1 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO04395.1 - 7.1e-05 21.1 5.8 0.38 8.8 0.1 4.8 2 2 3 5 5 5 3 Nucleoporin Nup120/160 MMTV_SAg PF01054.12 ETO04396.1 - 0.067 12.0 0.2 0.093 11.6 0.1 1.2 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen DUF2346 PF09803.4 ETO04396.1 - 0.2 11.5 0.7 0.37 10.6 0.5 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2346) ubiquitin PF00240.18 ETO04397.1 - 1.3e-11 43.7 0.2 5.7e-11 41.6 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin family zf-C3HC4_2 PF13923.1 ETO04397.1 - 1.9e-06 27.7 3.3 0.00031 20.7 0.5 2.9 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO04397.1 - 6.2e-06 25.7 9.3 1.4e-05 24.6 0.3 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 ETO04397.1 - 9.3e-06 25.2 1.2 7.6e-05 22.3 0.1 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.1 ETO04397.1 - 0.00035 20.3 1.6 0.00035 20.3 1.1 3.5 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_4 PF15227.1 ETO04397.1 - 0.0004 20.2 6.5 0.0015 18.3 0.4 3.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 ETO04397.1 - 0.00053 19.6 8.9 0.012 15.3 2.4 2.9 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_6 PF14835.1 ETO04397.1 - 0.026 14.2 4.1 2.7 7.8 0.1 2.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.1 ETO04397.1 - 0.63 9.7 13.4 0.02 14.5 3.3 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.16 ETO04397.1 - 4.2 7.3 14.9 1.4 8.8 2.1 3.2 3 0 0 3 3 3 0 IBR domain ABC2_membrane PF01061.19 ETO04398.1 - 0.00039 19.6 13.6 0.00039 19.6 9.4 2.1 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.7 ETO04398.1 - 0.003 17.1 0.4 0.0073 15.9 0.2 1.7 1 0 0 1 1 1 1 CDR ABC transporter WD40 PF00400.27 ETO04399.1 - 6.7e-13 47.9 1.6 4.4e-11 42.2 0.2 3.5 4 0 0 4 4 4 1 WD domain, G-beta repeat eIF2A PF08662.6 ETO04399.1 - 0.0045 16.7 0.1 0.21 11.2 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO04399.1 - 0.006 14.7 0.2 0.16 10.0 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF3140 PF11338.3 ETO04399.1 - 0.031 14.3 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) Xpo1 PF08389.7 ETO04399.1 - 0.081 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Exportin 1-like protein WD40 PF00400.27 ETO04400.1 - 1.7e-13 49.8 8.2 3.7e-10 39.2 0.1 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO04400.1 - 0.013 13.6 0.1 0.25 9.4 0.0 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Clathrin PF00637.15 ETO04401.1 - 1.1e-67 226.0 10.6 5.9e-28 97.2 0.1 4.9 5 0 0 5 5 5 3 Region in Clathrin and VPS Clathrin_H_link PF13838.1 ETO04401.1 - 1.3e-14 53.8 0.0 4.6e-14 52.0 0.0 2.1 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.15 ETO04402.1 - 6.6e-05 22.9 0.6 0.35 11.2 0.0 4.2 4 1 0 4 4 4 2 Clathrin propeller repeat YlzJ PF14035.1 ETO04404.1 - 0.018 15.1 0.8 0.079 13.0 0.0 2.4 2 0 0 2 2 2 0 YlzJ-like protein P3A PF08727.6 ETO04404.1 - 0.028 13.7 0.2 0.3 10.4 0.0 2.6 2 0 0 2 2 2 0 Poliovirus 3A protein like Chordopox_A35R PF05989.7 ETO04404.1 - 0.038 13.6 5.4 0.037 13.6 1.0 2.2 1 1 1 2 2 2 0 Chordopoxvirus A35R protein Cytochrome_C554 PF13435.1 ETO04404.1 - 0.097 12.7 6.1 0.035 14.1 2.6 1.5 2 0 0 2 2 2 0 Cytochrome c554 and c-prime GCC2_GCC3 PF07699.8 ETO04404.1 - 1.1 8.9 5.5 0.27 10.8 1.2 1.9 2 0 0 2 2 2 0 GCC2 and GCC3 DUF72 PF01904.13 ETO04405.1 - 0.017 14.8 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF72 SLS PF14611.1 ETO04405.1 - 0.072 12.4 1.8 0.12 11.8 1.2 1.4 1 1 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator GATase_2 PF00310.16 ETO04405.1 - 0.13 10.9 1.0 0.14 10.7 0.1 1.5 2 0 0 2 2 2 0 Glutamine amidotransferases class-II YajC PF02699.10 ETO04405.1 - 0.32 10.6 2.4 13 5.5 0.1 2.8 2 1 0 2 2 2 0 Preprotein translocase subunit KNTase_C PF07827.6 ETO04406.1 - 0.074 12.7 0.2 0.14 11.8 0.0 1.5 2 0 0 2 2 2 0 KNTase C-terminal domain IspA PF04279.10 ETO04406.1 - 0.18 11.7 5.0 0.19 11.6 3.5 1.2 1 0 0 1 1 1 0 Intracellular septation protein A CDC45 PF02724.9 ETO04407.1 - 0.026 12.5 9.7 0.029 12.4 6.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Myc_N PF01056.13 ETO04407.1 - 0.046 12.8 8.2 0.072 12.2 5.7 1.2 1 0 0 1 1 1 0 Myc amino-terminal region CENP-B_dimeris PF09026.5 ETO04407.1 - 3.2 8.0 10.2 6.6 7.0 7.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PRP1_N PF06424.7 ETO04407.1 - 8.8 6.6 24.1 0.56 10.5 12.3 2.1 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal WD40 PF00400.27 ETO04409.1 - 9.9e-68 221.8 16.1 8.6e-12 44.4 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO04409.1 - 1.1e-11 43.5 2.8 0.0001 20.6 0.3 5.0 1 1 4 5 5 5 4 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO04409.1 - 8e-05 22.3 2.5 0.15 11.8 0.1 4.1 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region SUKH_5 PF14567.1 ETO04409.1 - 0.2 11.0 1.9 0.95 8.9 0.0 2.8 3 1 1 4 4 4 0 SMI1-KNR4 cell-wall Kelch_6 PF13964.1 ETO04409.1 - 2.2 8.6 8.2 23 5.3 0.1 4.7 4 1 1 5 5 5 0 Kelch motif Cofilin_ADF PF00241.15 ETO04410.1 - 0.0025 17.6 0.6 0.0036 17.1 0.4 1.5 1 1 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF3586 PF12131.3 ETO04411.1 - 0.0064 16.5 5.1 1.3 9.1 0.3 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3586) I-set PF07679.11 ETO04412.1 - 0.016 15.0 0.3 0.05 13.4 0.2 1.8 1 0 0 1 1 1 0 Immunoglobulin I-set domain SPRY PF00622.23 ETO04412.1 - 0.053 13.6 0.1 0.053 13.6 0.1 2.3 2 1 0 2 2 2 0 SPRY domain DUF3385 PF11865.3 ETO04412.1 - 2 8.3 5.1 0.24 11.3 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) RP-C_C PF11800.3 ETO04414.1 - 0.011 15.5 0.9 0.013 15.2 0.6 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF4615 PF15393.1 ETO04414.1 - 0.021 15.0 4.2 0.024 14.8 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) DUF493 PF04359.9 ETO04414.1 - 0.038 14.3 1.6 0.068 13.5 0.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF493) FKBP_N PF01346.13 ETO04414.1 - 0.046 13.7 4.7 0.066 13.2 3.2 1.3 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Transposase_24 PF03004.9 ETO04414.1 - 0.19 11.6 3.0 0.28 11.0 2.0 1.3 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) G0-G1_switch_2 PF15103.1 ETO04414.1 - 0.68 10.1 3.0 1.1 9.4 2.1 1.4 1 1 0 1 1 1 0 G0/G1 switch protein 2 DUF4163 PF13739.1 ETO04414.1 - 2 9.2 5.9 3 8.6 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4163) DUF4140 PF13600.1 ETO04415.1 - 0.89 10.0 9.3 0.2 12.1 1.9 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) ubiquitin PF00240.18 ETO04416.1 - 8.2e-10 37.9 0.1 8.2e-10 37.9 0.1 2.3 3 0 0 3 3 3 1 Ubiquitin family Rad60-SLD PF11976.3 ETO04416.1 - 3.5e-07 29.7 0.1 1.3e-06 28.0 0.1 2.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like AATF-Che1 PF13339.1 ETO04416.1 - 0.015 15.4 6.6 0.079 13.1 1.6 2.8 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Telomere_reg-2 PF10193.4 ETO04416.1 - 0.019 15.2 0.4 0.058 13.6 0.0 2.0 2 0 0 2 2 2 0 Telomere length regulation protein DinB PF05163.7 ETO04416.1 - 0.019 14.6 0.1 0.04 13.6 0.1 1.5 1 0 0 1 1 1 0 DinB family DUF3972 PF13118.1 ETO04416.1 - 0.031 14.3 0.4 0.031 14.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) UN_NPL4 PF11543.3 ETO04416.1 - 0.052 13.8 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Spectrin PF00435.16 ETO04416.1 - 0.075 13.3 3.5 1.6 9.0 0.3 2.7 2 0 0 2 2 2 0 Spectrin repeat SlyX PF04102.7 ETO04416.1 - 0.59 10.5 6.2 0.14 12.4 0.7 2.5 2 0 0 2 2 2 0 SlyX PEP-utilisers_N PF05524.8 ETO04416.1 - 0.61 9.8 3.6 0.42 10.4 0.4 2.1 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal rve PF00665.21 ETO04417.1 - 2.8e-29 101.6 0.0 5.3e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 ETO04417.1 - 4.4e-06 26.1 0.2 5.5e-05 22.5 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain HEPN PF05168.9 ETO04417.1 - 0.0046 16.8 0.2 0.027 14.3 0.1 2.2 2 0 0 2 2 2 1 HEPN domain DDE_Tnp_IS240 PF13610.1 ETO04417.1 - 0.0048 16.8 0.1 0.016 15.1 0.0 1.9 2 0 0 2 2 2 1 DDE domain zf-H2C2 PF09337.5 ETO04417.1 - 0.021 14.2 0.0 0.063 12.6 0.0 1.9 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger MIF4G PF02854.14 ETO04418.1 - 2.6e-06 27.0 1.1 5.6e-06 25.9 0.8 1.5 1 0 0 1 1 1 1 MIF4G domain Adaptin_binding PF10199.4 ETO04418.1 - 0.0074 16.5 6.2 0.029 14.6 0.1 3.0 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 RP-C_C PF11800.3 ETO04418.1 - 0.012 15.3 5.3 0.11 12.1 0.3 2.9 3 0 0 3 3 3 0 Replication protein C C-terminal region E7 PF00527.13 ETO04419.1 - 0.025 14.7 4.0 0.03 14.4 0.2 2.1 2 0 0 2 2 2 0 E7 protein, Early protein UPF0179 PF03684.8 ETO04419.1 - 0.12 11.9 2.7 0.23 11.0 0.3 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0179) Ras PF00071.17 ETO04420.1 - 5.9e-44 149.3 0.2 5.9e-44 149.3 0.1 2.1 2 0 0 2 2 2 1 Ras family Miro PF08477.8 ETO04420.1 - 8.7e-14 52.0 0.1 8.7e-14 52.0 0.0 2.3 3 0 0 3 3 3 1 Miro-like protein Arf PF00025.16 ETO04420.1 - 1.4e-07 30.9 0.1 1.4e-07 30.9 0.1 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family PP_M1 PF03012.9 ETO04421.1 - 0.033 13.5 0.4 0.035 13.4 0.3 1.0 1 0 0 1 1 1 0 Phosphoprotein DUF2577 PF10844.3 ETO04421.1 - 0.061 13.3 0.0 0.085 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2577) DUF3857 PF12969.2 ETO04421.1 - 0.085 12.4 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3857) Ribosomal_S27e PF01667.12 ETO04422.1 - 0.046 13.2 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S27 Beach PF02138.13 ETO04424.1 - 3.8e-95 318.3 1.5 3.8e-95 318.3 1.0 2.8 3 0 0 3 3 3 1 Beige/BEACH domain PH_BEACH PF14844.1 ETO04424.1 - 1.1e-09 38.0 0.5 4.6e-09 36.0 0.4 2.1 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 ETO04424.1 - 4.6e-09 35.8 0.5 1.1e-05 25.0 0.1 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF1088 PF06469.6 ETO04424.1 - 0.00098 18.5 0.2 0.00098 18.5 0.1 2.5 2 1 1 3 3 3 1 Domain of Unknown Function (DUF1088) Aa_trans PF01490.13 ETO04426.1 - 1.5e-19 69.8 19.0 1.7e-19 69.6 13.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2730 PF10805.3 ETO04426.1 - 0.079 12.6 1.2 0.091 12.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) DoxX_3 PF13781.1 ETO04426.1 - 9.2 6.6 11.2 0.62 10.4 0.2 3.2 1 1 3 4 4 4 0 DoxX-like family CDC45 PF02724.9 ETO04427.1 - 0.00028 19.0 11.9 0.00028 19.0 8.2 2.6 2 1 0 2 2 2 1 CDC45-like protein MIP-T3 PF10243.4 ETO04427.1 - 0.00028 19.4 21.8 0.00028 19.4 15.1 2.1 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 Daxx PF03344.10 ETO04427.1 - 0.15 10.4 61.0 0.022 13.2 24.1 2.2 2 0 0 2 2 2 0 Daxx Family DUF3439 PF11921.3 ETO04427.1 - 0.34 10.6 11.8 0.81 9.4 8.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Nop14 PF04147.7 ETO04427.1 - 0.94 7.3 68.2 0.16 9.8 27.1 2.1 2 0 0 2 2 2 0 Nop14-like family SAPS PF04499.10 ETO04427.1 - 6.9 5.1 29.4 3.2 6.2 5.4 2.4 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein WD40 PF00400.27 ETO04428.1 - 6.4e-33 111.4 2.3 1.3e-11 43.9 0.3 3.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO04428.1 - 7.6e-07 27.6 0.2 0.0015 16.7 0.0 2.9 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Kelch_5 PF13854.1 ETO04429.1 - 0.0019 18.1 0.2 2.5 8.1 0.0 2.7 3 0 0 3 3 3 2 Kelch motif Copper-bind PF00127.15 ETO04429.1 - 0.18 12.0 0.1 0.18 12.0 0.1 1.8 2 1 0 2 2 2 0 Copper binding proteins, plastocyanin/azurin family WD40 PF00400.27 ETO04430.1 - 2.6e-64 210.9 22.2 2.7e-11 42.8 0.5 7.1 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO04430.1 - 1.2e-15 56.6 1.0 0.0054 14.9 0.0 6.0 2 1 4 6 6 6 6 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO04430.1 - 4.2e-07 30.2 2.3 1.6e-06 28.3 1.6 2.1 1 0 0 1 1 1 1 TRAF-type zinc finger COBRA1 PF06209.8 ETO04431.1 - 0.058 11.9 2.5 0.065 11.8 1.7 1.0 1 0 0 1 1 1 0 Cofactor of BRCA1 (COBRA1) DUF2681 PF10883.3 ETO04431.1 - 0.43 10.8 9.7 0.61 10.3 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Tweety PF04906.8 ETO04431.1 - 0.72 8.1 3.7 0.71 8.2 1.9 1.5 1 1 1 2 2 2 0 Tweety Atg14 PF10186.4 ETO04431.1 - 1.2 7.9 9.1 1.3 7.8 6.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2228 PF10228.4 ETO04431.1 - 6 6.3 11.2 7.1 6.1 7.7 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) Peroxin-13_N PF04088.8 ETO04431.1 - 6.8 6.6 6.3 9 6.2 4.4 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region ATP-synt_C PF00137.16 ETO04432.1 - 4.3e-15 55.3 8.9 6.4e-15 54.8 6.1 1.3 1 0 0 1 1 1 1 ATP synthase subunit C UbiA PF01040.13 ETO04432.1 - 0.006 15.8 1.4 0.0069 15.6 1.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family RebB PF11747.3 ETO04432.1 - 0.084 12.7 0.2 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Killing trait SAM_2 PF07647.12 ETO04433.1 - 3.8e-09 36.2 0.0 8.5e-09 35.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO04433.1 - 7e-07 29.3 0.0 1.4e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) TPR_12 PF13424.1 ETO04434.1 - 1.5e-66 220.2 14.9 1e-23 83.0 0.1 5.0 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.23 ETO04434.1 - 1.6e-41 138.2 46.9 1.2e-08 34.1 1.1 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 ETO04434.1 - 1.5e-40 133.8 31.2 2.2e-07 30.2 0.2 7.2 6 1 1 7 7 7 7 Tetratricopeptide repeat TPR_11 PF13414.1 ETO04434.1 - 2.2e-40 136.1 23.9 7.2e-13 47.9 2.0 4.5 2 1 1 4 4 4 4 TPR repeat TPR_8 PF13181.1 ETO04434.1 - 6.4e-37 122.5 45.5 2e-07 30.3 0.8 7.2 6 1 1 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.1 ETO04434.1 - 2.6e-34 114.2 15.3 4.3e-05 22.9 0.1 7.1 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_10 PF13374.1 ETO04434.1 - 8.5e-26 89.0 0.0 6.6e-05 22.7 0.0 7.2 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 ETO04434.1 - 9.1e-17 60.0 0.0 0.013 16.0 0.0 6.9 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO04434.1 - 5.5e-16 57.8 10.5 0.014 15.7 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO04434.1 - 1.5e-13 49.7 21.5 0.0058 16.7 0.2 7.1 6 2 1 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO04434.1 - 2.7e-13 50.1 0.7 2.6e-05 24.7 0.0 5.9 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_3 PF07720.7 ETO04434.1 - 1.6e-09 37.3 27.6 0.052 13.3 0.3 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.1 ETO04434.1 - 1.2e-08 35.1 7.1 0.00033 20.9 0.1 4.7 3 2 3 6 6 5 3 Tetratricopeptide repeat MIT PF04212.13 ETO04434.1 - 2.8e-08 33.5 27.9 0.16 11.8 0.1 6.2 5 1 1 6 6 6 5 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 ETO04434.1 - 2.4e-07 30.7 22.5 0.0013 18.8 3.1 4.4 2 2 2 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 ETO04434.1 - 2.2e-06 27.4 0.0 0.0062 16.3 0.0 4.4 5 1 1 6 6 6 1 Tetratricopeptide repeat Sel1 PF08238.7 ETO04434.1 - 3.5e-05 24.2 16.2 19 6.0 0.0 7.1 7 0 0 7 7 7 0 Sel1 repeat DUF2225 PF09986.4 ETO04434.1 - 0.00016 21.1 13.1 0.22 10.9 0.2 3.5 1 1 2 3 3 3 3 Uncharacterized protein conserved in bacteria (DUF2225) SHNi-TPR PF10516.4 ETO04434.1 - 0.00037 19.6 7.4 1.2 8.4 0.0 5.7 5 1 1 6 6 6 1 SHNi-TPR Clathrin PF00637.15 ETO04434.1 - 0.028 14.0 24.6 0.056 13.0 3.5 4.1 2 1 1 3 3 3 0 Region in Clathrin and VPS PPR PF01535.15 ETO04434.1 - 0.044 13.7 9.3 4.8 7.3 0.0 5.7 7 0 0 7 7 7 0 PPR repeat Fis1_TPR_C PF14853.1 ETO04434.1 - 0.86 9.5 26.4 5.7 6.9 0.0 6.4 6 1 1 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat Metallophos PF00149.23 ETO04437.1 - 0.0001 21.7 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Mito_fiss_reg PF05308.6 ETO04437.1 - 0.00037 19.9 1.7 0.00052 19.4 1.2 1.3 1 0 0 1 1 1 1 Mitochondrial fission regulator CAP_N PF01213.14 ETO04437.1 - 0.0028 16.9 1.6 0.0037 16.6 1.1 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal Metallophos PF00149.23 ETO04438.1 - 6.2e-15 55.1 0.0 9.6e-15 54.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UPF0060 PF02694.10 ETO04438.1 - 0.0088 16.0 3.9 0.017 15.1 0.9 2.2 2 0 0 2 2 2 1 Uncharacterised BCR, YnfA/UPF0060 family GGDEF PF00990.16 ETO04438.1 - 0.01 15.3 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 GGDEF domain DUF4131 PF13567.1 ETO04438.1 - 0.11 11.8 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) CENP-B_dimeris PF09026.5 ETO04441.1 - 0.097 12.9 3.7 1.8 8.8 0.4 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF4611 PF15387.1 ETO04441.1 - 2.7 8.2 6.8 8.8 6.5 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 ETO04441.1 - 2.8 7.4 6.7 22 4.5 3.6 2.1 2 0 0 2 2 2 0 Nucleoplasmin Kinesin PF00225.18 ETO04442.1 - 7.4e-21 74.2 1.2 1e-20 73.7 0.9 1.2 1 0 0 1 1 1 1 Kinesin motor domain Peptidase_C93 PF06035.6 ETO04442.1 - 0.018 14.4 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial transglutaminase-like cysteine proteinase BTLCP Mito_fiss_reg PF05308.6 ETO04443.1 - 9.1 5.5 17.6 5.7 6.2 10.8 1.7 1 1 1 2 2 2 0 Mitochondrial fission regulator Chromo PF00385.19 ETO04444.1 - 3.2e-11 42.7 2.5 3.2e-11 42.7 1.7 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF481 PF04338.7 ETO04444.1 - 0.1 12.3 0.1 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF481 RNase_PH PF01138.16 ETO04444.1 - 7.6 6.8 8.0 4.3 7.6 0.0 2.3 1 1 1 2 2 2 0 3' exoribonuclease family, domain 1 Chromo PF00385.19 ETO04445.1 - 0.0033 17.0 0.8 0.0074 15.9 0.6 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain GBP_C PF02841.9 ETO04445.1 - 0.13 11.3 9.3 0.2 10.8 6.4 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Lipoprotein_19 PF13617.1 ETO04445.1 - 0.54 9.9 4.7 1.9 8.1 1.5 2.2 2 0 0 2 2 2 0 YnbE-like lipoprotein Ras PF00071.17 ETO04447.1 - 1.4e-47 161.0 0.0 1.8e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO04447.1 - 1.1e-14 54.9 0.0 3.7e-14 53.2 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO04447.1 - 1.1e-07 31.2 0.0 1.5e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO04447.1 - 0.016 14.6 0.3 0.11 11.9 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Lipase_GDSL_3 PF14606.1 ETO04447.1 - 0.099 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DUF912 PF06024.7 ETO04448.1 - 0.085 12.9 2.0 6 6.9 0.1 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Amidohydro_2 PF04909.9 ETO04449.1 - 7.4e-21 74.9 0.0 1.4e-20 73.9 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase Exonuc_VII_S PF02609.11 ETO04449.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Exonuclease VII small subunit TLD PF07534.11 ETO04450.1 - 5.4e-11 42.6 0.3 1.3e-10 41.4 0.2 1.6 1 0 0 1 1 1 1 TLD DUF2487 PF10673.4 ETO04450.1 - 0.014 15.1 0.5 5.2 6.8 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2487) zf-rbx1 PF12678.2 ETO04450.1 - 0.091 12.8 0.8 0.79 9.8 0.0 2.6 3 0 0 3 3 3 0 RING-H2 zinc finger DUF1632 PF07857.7 ETO04451.1 - 0.074 12.2 0.6 0.42 9.8 0.0 2.1 2 0 0 2 2 2 0 CEO family (DUF1632) 60KD_IMP PF02096.15 ETO04452.1 - 2.7e-18 66.3 2.1 2.7e-18 66.3 1.5 1.6 2 0 0 2 2 2 1 60Kd inner membrane protein F_actin_bind PF08919.5 ETO04452.1 - 0.21 11.2 1.4 8.3 6.1 0.2 2.5 2 0 0 2 2 2 0 F-actin binding WD40 PF00400.27 ETO04454.1 - 7.8e-33 111.1 17.1 9e-12 44.4 0.3 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO04454.1 - 1.1e-09 36.9 0.7 0.029 12.5 0.0 4.1 2 2 2 4 4 4 4 Nucleoporin Nup120/160 Glyco_transf_8 PF01501.15 ETO04457.1 - 7.1e-18 64.8 0.1 1.1e-17 64.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 ETO04457.1 - 0.0011 18.4 1.1 0.0012 18.2 0.5 1.7 1 1 0 1 1 1 1 Mannosyltransferase putative Ribosomal_L7Ae PF01248.21 ETO04457.1 - 0.0088 15.5 0.0 0.019 14.4 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ANAPC15 PF15243.1 ETO04460.1 - 0.12 12.5 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 WD40 PF00400.27 ETO04462.1 - 1e-05 25.2 0.2 5e-05 23.0 0.2 2.0 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF2098 PF09871.4 ETO04465.1 - 0.0031 17.4 0.3 0.0031 17.4 0.2 2.3 1 1 1 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2098) Phage_connect_1 PF05135.8 ETO04465.1 - 0.01 15.9 2.0 0.017 15.2 0.5 2.0 1 1 2 3 3 3 0 Phage gp6-like head-tail connector protein EMP24_GP25L PF01105.19 ETO04465.1 - 0.012 15.2 0.2 0.012 15.2 0.1 1.6 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Lebercilin PF15619.1 ETO04465.1 - 0.034 13.5 5.5 0.11 11.8 0.8 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Z1 PF10593.4 ETO04465.1 - 0.25 10.5 5.2 3.4 6.8 0.3 2.0 2 0 0 2 2 2 0 Z1 domain UPF0122 PF04297.9 ETO04465.1 - 0.29 11.1 7.1 0.073 13.0 2.2 1.9 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like rve_3 PF13683.1 ETO04465.1 - 0.35 10.4 1.4 2.3 7.8 0.1 2.8 2 1 1 3 3 3 0 Integrase core domain Stap_Strp_toxin PF01123.15 ETO04465.1 - 0.54 10.7 6.6 2.4 8.6 4.6 2.0 1 1 0 1 1 1 0 Staphylococcal/Streptococcal toxin, OB-fold domain TPR_MLP1_2 PF07926.7 ETO04465.1 - 2.6 7.8 9.1 57 3.4 6.3 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Salp15 PF12115.3 ETO04465.1 - 4.3 7.5 14.7 24 5.1 6.8 2.3 1 1 1 2 2 2 0 Salivary protein of 15kDa inhibits CD4+ T cell activation DUF2431 PF10354.4 ETO04467.1 - 0.082 12.8 3.6 0.12 12.3 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) DUF3540 PF12059.3 ETO04467.1 - 0.085 12.4 4.3 0.11 12.1 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3540) SecA_DEAD PF07517.9 ETO04468.1 - 9.5e-08 31.6 0.0 9.5e-08 31.6 0.0 4.9 4 1 2 6 6 6 1 SecA DEAD-like domain GlcNAc PF11397.3 ETO04471.1 - 1.9e-29 102.8 0.8 2.3e-29 102.5 0.5 1.0 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) WD40 PF00400.27 ETO04473.1 - 2.2e-29 100.2 3.4 1.3e-10 40.7 0.2 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO04473.1 - 0.032 12.3 0.2 0.51 8.4 0.2 2.3 2 1 0 2 2 2 0 Nucleoporin Nup120/160 DUF624 PF04854.9 ETO04473.1 - 0.34 10.8 5.7 0.7 9.7 2.5 2.5 2 1 0 2 2 2 0 Protein of unknown function, DUF624 Nnf1 PF03980.9 ETO04474.1 - 0.038 13.9 0.6 0.053 13.5 0.4 1.3 1 0 0 1 1 1 0 Nnf1 Atg14 PF10186.4 ETO04474.1 - 0.095 11.6 1.7 0.099 11.5 1.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Bro-N PF02498.12 ETO04474.1 - 1.5 9.1 5.8 2.2 8.6 4.0 1.4 1 1 0 1 1 1 0 BRO family, N-terminal domain Kelch_1 PF01344.20 ETO04475.1 - 0.0099 15.4 0.8 9.6 5.8 0.0 4.2 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 ETO04475.1 - 0.02 15.0 0.1 12 6.2 0.0 4.1 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.1 ETO04475.1 - 0.032 13.9 0.1 1.7 8.5 0.0 3.6 4 1 1 5 5 5 0 Galactose oxidase, central domain Toxin_1 PF00087.16 ETO04476.1 - 0.12 12.8 0.6 0.17 12.2 0.4 1.3 1 1 0 1 1 1 0 Snake toxin DUF3293 PF11697.3 ETO04476.1 - 0.12 12.4 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3293) zf-MIZ PF02891.15 ETO04476.1 - 0.43 10.1 2.4 0.48 9.9 0.8 1.7 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger WD40 PF00400.27 ETO04477.1 - 2.6e-67 220.4 9.8 4e-13 48.7 0.1 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO04477.1 - 2.7e-09 35.7 13.7 0.0064 14.6 0.2 6.9 2 1 4 7 7 7 5 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO04477.1 - 3.9e-09 35.3 0.9 0.00013 20.4 0.2 3.8 2 1 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.7 ETO04477.1 - 1.5e-06 27.6 4.7 2.1 8.1 0.0 6.2 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 ETO04477.1 - 4.7e-06 25.4 0.0 1.2 7.6 0.0 4.7 1 1 4 5 5 5 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nucleoporin_N PF08801.6 ETO04477.1 - 5.4e-05 22.1 8.3 0.018 13.7 1.6 4.9 1 1 3 4 4 4 1 Nup133 N terminal like Str_synth PF03088.11 ETO04477.1 - 0.0012 18.8 0.0 0.093 12.7 0.0 3.7 3 1 2 5 5 5 1 Strictosidine synthase SGL PF08450.7 ETO04477.1 - 0.0019 17.6 0.4 1.6 8.0 0.0 3.1 1 1 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Hira PF07569.6 ETO04477.1 - 0.0023 17.1 0.6 6.8 5.8 0.0 4.6 2 1 3 5 5 5 1 TUP1-like enhancer of split Gmad1 PF10647.4 ETO04477.1 - 0.0042 16.5 0.2 1.7 7.9 0.0 3.4 1 1 2 3 3 3 1 Lipoprotein LpqB beta-propeller domain Nbas_N PF15492.1 ETO04477.1 - 0.015 14.4 0.9 8 5.4 0.0 4.0 1 1 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 ETO04477.1 - 0.14 11.4 6.4 3.8 6.9 0.0 4.6 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Trypan_PARP PF05887.6 ETO04479.1 - 0.0067 16.2 7.3 0.0067 16.2 5.1 1.6 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) DNA_pol_A_exo1 PF01612.15 ETO04479.1 - 0.0083 15.6 3.5 0.12 11.7 1.3 2.8 3 1 1 4 4 4 1 3'-5' exonuclease Neisseria_TspB PF05616.8 ETO04479.1 - 0.44 8.8 4.0 0.67 8.2 2.8 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein SAM_2 PF07647.12 ETO04482.1 - 0.00015 21.5 0.2 0.0011 18.7 0.1 2.5 2 1 0 2 2 2 1 SAM domain (Sterile alpha motif) TPR_12 PF13424.1 ETO04483.1 - 1.1e-26 92.5 7.6 9e-14 51.1 0.2 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO04483.1 - 3e-15 55.6 9.3 1.8e-08 33.9 0.7 2.2 1 1 1 2 2 2 2 TPR repeat TPR_7 PF13176.1 ETO04483.1 - 1.6e-11 43.0 0.2 0.015 15.0 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO04483.1 - 1.6e-11 43.2 5.8 0.00035 20.0 1.4 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO04483.1 - 3.7e-11 42.0 3.3 0.0047 16.7 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO04483.1 - 4.2e-11 42.4 0.0 0.0075 16.1 0.0 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO04483.1 - 2.5e-09 36.2 4.9 0.0039 16.8 1.4 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat SNAP PF14938.1 ETO04483.1 - 1.5e-07 30.8 0.2 1.8e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.1 ETO04483.1 - 0.0014 18.9 0.0 1.5 9.4 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat APG17 PF04108.7 ETO04483.1 - 0.0029 16.4 3.3 0.0031 16.3 2.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 Uteroglobin PF01099.12 ETO04483.1 - 0.0077 16.0 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Uteroglobin family OspD PF03207.8 ETO04483.1 - 0.017 14.2 0.1 0.023 13.8 0.1 1.1 1 0 0 1 1 1 0 Borrelia outer surface protein D (OspD) SHNi-TPR PF10516.4 ETO04483.1 - 0.029 13.6 0.1 7.5 5.8 0.0 2.9 3 0 0 3 3 3 0 SHNi-TPR TPR_16 PF13432.1 ETO04483.1 - 0.047 14.3 0.0 4.6 8.0 0.0 2.6 1 1 2 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.4 ETO04483.1 - 0.049 13.0 1.5 1.7 8.0 0.0 2.3 1 1 1 2 2 2 0 26S proteasome subunit RPN7 TPR_17 PF13431.1 ETO04483.1 - 0.064 13.4 0.4 5.8 7.3 0.0 3.5 3 2 0 3 3 3 0 Tetratricopeptide repeat DUF627 PF04781.7 ETO04483.1 - 0.075 12.6 0.3 0.15 11.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF627) Apc3 PF12895.2 ETO04483.1 - 0.12 12.5 5.9 1.1 9.4 4.1 2.4 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 NSF PF02071.15 ETO04483.1 - 1 10.2 5.0 7.8 7.5 0.2 3.9 5 0 0 5 5 3 0 Aromatic-di-Alanine (AdAR) repeat PCNA_C PF02747.10 ETO04484.1 - 4.1e-49 165.7 0.0 7.1e-49 164.9 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.13 ETO04484.1 - 5.4e-44 148.7 2.0 9.8e-44 147.9 1.4 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.11 ETO04484.1 - 3.1e-07 29.4 0.2 1.1e-05 24.3 0.1 2.3 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 ETO04484.1 - 0.00033 19.8 0.0 0.00038 19.6 0.0 1.2 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 ETO04484.1 - 0.023 13.6 0.0 0.034 13.0 0.0 1.4 1 0 0 1 1 1 0 Hus1-like protein DUF4208 PF13907.1 ETO04485.1 - 0.018 15.2 1.9 0.023 14.9 0.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4208) DUF2480 PF10652.4 ETO04485.1 - 0.019 14.5 0.1 0.046 13.2 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2480) Rap_GAP PF02145.10 ETO04486.1 - 2.8e-51 173.5 0.4 1.3e-50 171.4 0.0 2.4 2 0 0 2 2 2 1 Rap/ran-GAP UPF0565 PF10561.4 ETO04487.1 - 1.7e-40 138.8 13.9 3.4e-23 82.0 2.9 3.6 3 1 1 4 4 4 3 Uncharacterised protein family UPF0565 DUF4050 PF13259.1 ETO04487.1 - 0.086 12.7 0.4 0.17 11.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) BUD22 PF09073.5 ETO04487.1 - 0.15 11.1 1.3 0.25 10.3 0.9 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 ETO04487.1 - 0.24 9.3 3.6 0.062 11.2 0.3 1.6 2 0 0 2 2 2 0 Nop14-like family PI3K_p85B PF02192.11 ETO04488.1 - 0.013 14.9 0.3 0.032 13.6 0.1 1.8 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain TPR_12 PF13424.1 ETO04489.1 - 1.3e-27 95.4 6.1 2.4e-15 56.2 0.7 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO04489.1 - 1.7e-13 50.0 0.4 7.4e-07 28.9 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO04489.1 - 9.2e-13 47.6 15.8 1.5e-08 34.1 2.1 3.1 1 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 ETO04489.1 - 6.1e-12 44.6 22.5 1.4e-07 30.7 1.6 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO04489.1 - 6.6e-11 41.1 26.4 0.00018 21.0 0.6 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO04489.1 - 1.2e-10 40.4 23.6 2.6e-05 23.7 1.1 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO04489.1 - 2.3e-09 36.3 8.7 8.4e-05 22.0 0.1 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO04489.1 - 3.3e-08 33.9 0.0 0.0025 18.4 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO04489.1 - 2.4e-05 24.1 3.7 0.0033 17.5 0.2 3.7 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO04489.1 - 0.00067 19.9 3.9 0.62 10.6 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat C6_DPF PF10170.4 ETO04489.1 - 0.016 15.2 0.7 0.12 12.3 0.0 2.7 3 0 0 3 3 3 0 Cysteine-rich domain Apc3 PF12895.2 ETO04489.1 - 0.087 12.9 14.6 0.064 13.3 2.0 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 ETO04489.1 - 0.11 13.1 0.0 56 4.7 0.1 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETO04489.1 - 0.88 9.9 6.6 13 6.1 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.7 ETO04489.1 - 5.3 7.8 8.9 8.3 7.1 0.4 3.5 3 0 0 3 3 3 0 Sel1 repeat WD40 PF00400.27 ETO04491.1 - 6.8e-20 70.1 7.3 1.9e-09 37.0 0.7 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO04491.1 - 8.7e-08 30.7 0.9 2.2e-05 22.8 0.1 2.3 2 1 0 2 2 2 2 Nucleoporin Nup120/160 DUF1914 PF08932.5 ETO04491.1 - 0.13 12.2 0.8 4.6 7.3 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1914) TRAM_LAG1_CLN8 PF03798.11 ETO04491.1 - 0.59 9.6 6.3 0.15 11.5 1.7 1.7 2 0 0 2 2 2 0 TLC domain DUF3800 PF12686.2 ETO04492.1 - 0.33 10.5 4.8 0.42 10.2 3.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) VTC PF09359.5 ETO04493.1 - 0.0027 16.7 1.3 0.0031 16.5 0.9 1.1 1 0 0 1 1 1 1 VTC domain TPR_12 PF13424.1 ETO04494.1 - 5.7e-14 51.8 2.6 1.5e-07 31.2 0.2 2.6 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO04494.1 - 1.1e-12 46.9 5.2 4.6e-07 29.1 0.4 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO04494.1 - 4.8e-11 41.6 9.2 1e-05 25.0 0.1 3.7 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO04494.1 - 7.4e-11 41.5 0.9 6.2e-10 38.5 0.2 2.5 3 1 0 3 3 3 1 TPR repeat TPR_8 PF13181.1 ETO04494.1 - 2.8e-10 39.2 1.8 0.00047 19.7 0.2 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO04494.1 - 1.3e-07 31.2 0.0 0.0045 16.8 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO04494.1 - 1.4e-07 30.8 0.6 0.00011 21.7 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO04494.1 - 1.2e-05 25.0 6.7 0.00023 20.9 1.0 2.8 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.1 ETO04494.1 - 4.1e-05 23.8 0.0 0.18 12.5 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO04494.1 - 0.00031 20.8 6.1 0.00044 20.3 0.9 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETO04494.1 - 0.00051 20.3 0.6 0.3 11.6 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO04494.1 - 0.0023 18.0 5.3 0.99 9.7 0.0 4.2 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO04494.1 - 0.023 15.3 0.0 3.6 8.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETO04494.1 - 0.038 14.3 0.0 0.22 11.8 0.0 2.2 2 1 1 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.27 ETO04496.1 - 1.9e-13 49.7 11.8 8.5e-10 38.1 2.6 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat TPR_11 PF13414.1 ETO04496.1 - 0.00064 19.3 0.1 0.00092 18.8 0.0 1.2 1 0 0 1 1 1 1 TPR repeat TPR_17 PF13431.1 ETO04496.1 - 0.01 15.9 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat SAPS PF04499.10 ETO04498.1 - 0.029 13.0 9.5 0.037 12.6 6.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DHHW PF14286.1 ETO04498.1 - 0.11 11.8 11.5 0.18 11.1 8.0 1.4 1 0 0 1 1 1 0 DHHW protein Podoplanin PF05808.6 ETO04498.1 - 0.23 11.0 0.9 0.29 10.6 0.6 1.2 1 0 0 1 1 1 0 Podoplanin LMBR1 PF04791.11 ETO04498.1 - 0.46 8.9 3.5 0.59 8.6 2.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2413 PF10310.4 ETO04498.1 - 1.1 8.0 20.8 1.5 7.5 14.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Paramyxo_ncap PF00973.14 ETO04498.1 - 1.9 7.0 10.6 2.4 6.7 7.3 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Trypan_PARP PF05887.6 ETO04498.1 - 3.4 7.4 11.9 4.6 7.0 8.2 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Cytomega_UL84 PF06284.6 ETO04498.1 - 3.4 5.9 6.6 3.7 5.8 4.6 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Sec10 PF07393.6 ETO04498.1 - 4 5.5 15.0 5.1 5.1 10.4 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec10 RP-C_C PF11800.3 ETO04498.1 - 4.4 6.9 10.6 6.1 6.4 7.4 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region GAGA_bind PF06217.7 ETO04498.1 - 8.4 6.2 16.7 11 5.9 11.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Hid1 PF12722.2 ETO04498.1 - 9.9 3.6 16.8 12 3.3 11.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ank PF00023.25 ETO04499.1 - 2.3e-11 42.9 0.2 1.6e-08 33.9 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 ETO04499.1 - 3.1e-10 40.2 0.1 5.4e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO04499.1 - 2.6e-08 33.3 0.3 1.1e-05 25.1 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 ETO04499.1 - 6e-05 23.4 0.0 0.0003 21.2 0.0 2.1 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO04499.1 - 0.00011 22.3 0.1 0.00022 21.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF4473 PF14747.1 ETO04502.1 - 0.13 12.4 0.1 0.22 11.7 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4473) Endonuc-BglII PF09195.6 ETO04503.1 - 0.016 14.6 0.2 0.02 14.3 0.1 1.2 1 0 0 1 1 1 0 Restriction endonuclease BglII TPR_12 PF13424.1 ETO04504.1 - 2.3e-17 62.7 0.7 1.4e-07 31.3 0.0 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO04504.1 - 9.8e-10 37.9 18.3 4.5e-05 22.9 0.2 3.2 1 1 3 4 4 4 4 TPR repeat TPR_1 PF00515.23 ETO04504.1 - 1.2e-08 34.1 10.4 8.9e-06 25.1 0.1 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO04504.1 - 2.7e-08 33.4 0.0 0.0001 22.0 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO04504.1 - 3.7e-08 32.5 0.3 0.0079 15.9 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO04504.1 - 2e-07 30.3 4.8 0.0011 18.7 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO04504.1 - 0.0019 17.8 11.4 0.012 15.3 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO04504.1 - 0.058 13.8 0.1 12 6.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1194 PF06707.6 ETO04504.1 - 0.063 12.2 0.2 0.15 10.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1194) DUF4181 PF13789.1 ETO04505.1 - 0.61 10.0 0.0 0.61 10.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) DUF3306 PF11748.3 ETO04506.1 - 0.021 15.4 2.2 0.021 15.4 1.5 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) DUF2681 PF10883.3 ETO04506.1 - 0.083 13.0 0.2 0.083 13.0 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) DUF2072 PF09845.4 ETO04506.1 - 0.47 10.3 4.7 0.68 9.8 0.2 2.0 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) OAD_gamma PF04277.8 ETO04506.1 - 0.66 10.3 2.3 0.92 9.9 0.2 2.0 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain ETRAMP PF09716.5 ETO04506.1 - 1.7 8.6 10.2 0.69 9.9 0.1 2.3 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Exo_endo_phos PF03372.18 ETO04507.1 - 0.0044 16.9 0.0 0.0074 16.2 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.22 ETO04508.1 - 8.9e-13 48.0 0.0 1.6e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SBP_bac_3 PF00497.15 ETO04508.1 - 0.079 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 WD40 PF00400.27 ETO04510.1 - 1.9e-52 173.3 8.9 1.3e-13 50.2 0.1 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO04510.1 - 6e-05 21.9 7.4 0.5 9.0 0.0 3.8 1 1 3 4 4 4 3 Nup133 N terminal like Nbas_N PF15492.1 ETO04510.1 - 0.00034 19.7 0.6 0.022 13.8 0.1 2.7 1 1 2 3 3 3 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 ETO04510.1 - 0.00039 20.0 4.5 0.18 11.5 0.1 3.4 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO04510.1 - 0.025 14.0 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 PQQ-like domain NYD-SP28_assoc PF14775.1 ETO04510.1 - 0.027 14.1 0.2 36 4.1 0.0 3.8 4 0 0 4 4 4 0 Sperm tail C-terminal domain SusE PF14292.1 ETO04510.1 - 0.029 14.1 0.0 17 5.2 0.0 3.0 2 1 0 3 3 3 0 SusE outer membrane protein AcetylCoA_hyd_C PF13336.1 ETO04510.1 - 0.097 12.3 0.0 0.8 9.3 0.0 2.3 3 0 0 3 3 3 0 Acetyl-CoA hydrolase/transferase C-terminal domain Resistin PF06954.6 ETO04510.1 - 0.11 12.8 0.7 10 6.4 0.0 3.0 1 1 2 3 3 3 0 Resistin F420_ligase PF01996.11 ETO04510.1 - 0.12 11.3 0.0 0.43 9.6 0.0 1.7 1 1 1 2 2 2 0 F420-0:Gamma-glutamyl ligase DUF1611 PF07755.6 ETO04510.1 - 0.14 10.7 0.0 0.29 9.7 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1611) POLO_box PF00659.13 ETO04510.1 - 0.23 11.4 3.3 17 5.4 0.1 3.8 2 2 2 4 4 4 0 POLO box duplicated region RabGAP-TBC PF00566.13 ETO04511.1 - 1.4e-32 112.9 0.7 1.9e-32 112.5 0.5 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Dynein_light PF01221.13 ETO04512.1 - 3.6e-39 132.6 2.2 3.6e-39 132.6 1.5 2.4 3 0 0 3 3 3 1 Dynein light chain type 1 Actin PF00022.14 ETO04513.1 - 1.5e-19 69.7 0.0 2e-18 66.0 0.0 2.1 1 1 0 1 1 1 1 Actin Ecm33 PF12454.3 ETO04513.1 - 0.14 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Ras PF00071.17 ETO04515.1 - 1.5e-06 27.6 0.5 3.6e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Ras family Miro PF08477.8 ETO04515.1 - 7.1e-05 23.2 0.2 0.00016 22.1 0.2 1.7 1 1 0 1 1 1 1 Miro-like protein ABC_transp_aux PF09822.4 ETO04515.1 - 0.017 14.6 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 ABC-type uncharacterized transport system DUF2516 PF10724.4 ETO04515.1 - 0.075 13.0 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2516) DUF4188 PF13826.1 ETO04516.1 - 0.077 13.0 0.1 0.17 11.9 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4188) DUF1315 PF07023.7 ETO04517.1 - 1.7 8.5 6.4 2.1 8.2 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1315) Steroid_dh PF02544.11 ETO04518.1 - 0.072 12.8 2.4 0.15 11.8 0.2 2.3 2 1 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase NYD-SP28_assoc PF14775.1 ETO04519.1 - 0.00028 20.5 1.0 0.00028 20.5 0.7 4.2 3 1 0 3 3 3 1 Sperm tail C-terminal domain L27_N PF09060.5 ETO04520.1 - 0.072 12.8 0.3 0.22 11.3 0.2 1.8 1 0 0 1 1 1 0 L27_N FAM60A PF15396.1 ETO04520.1 - 0.5 10.0 9.5 0.75 9.5 6.6 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF2743 PF10899.3 ETO04521.1 - 0.009 15.4 0.2 0.013 14.8 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2743) WSS_VP PF12175.3 ETO04521.1 - 0.057 12.4 0.3 0.072 12.1 0.2 1.2 1 0 0 1 1 1 0 White spot syndrome virus structural envelope protein VP zf-RVT PF13966.1 ETO04522.1 - 2.1e-06 27.9 0.1 2.1e-06 27.9 0.1 3.1 2 2 1 3 3 3 1 zinc-binding in reverse transcriptase RNase_H PF00075.19 ETO04522.1 - 2.2e-05 24.7 0.0 3.9e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 RNase H Telomere_Sde2_2 PF13297.1 ETO04523.1 - 3.4e-24 83.8 0.1 7.9e-24 82.7 0.1 1.6 1 0 0 1 1 1 1 Telomere stability C-terminal DUF2175 PF09943.4 ETO04523.1 - 1.7 8.7 5.3 0.38 10.8 0.8 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) DUF848 PF05852.6 ETO04523.1 - 3.7 7.3 8.7 0.7 9.7 1.6 2.3 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) SET PF00856.23 ETO04525.1 - 2.2e-09 37.8 0.2 4.2e-09 36.9 0.1 1.5 1 0 0 1 1 1 1 SET domain DUF972 PF06156.8 ETO04526.1 - 0.0038 17.5 2.7 0.0038 17.5 1.8 3.2 1 1 2 3 3 3 1 Protein of unknown function (DUF972) bZIP_1 PF00170.16 ETO04526.1 - 0.0064 16.4 1.4 0.0064 16.4 1.0 4.0 4 1 1 5 5 5 1 bZIP transcription factor ALMT PF11744.3 ETO04526.1 - 0.089 11.4 12.0 0.13 10.8 8.2 1.3 1 1 0 1 1 1 0 Aluminium activated malate transporter SeleniumBinding PF11524.3 ETO04526.1 - 0.37 10.9 0.1 0.37 10.9 0.1 2.5 3 1 0 3 3 3 0 Selenium binding protein Fib_alpha PF08702.5 ETO04526.1 - 1.2 9.3 26.2 1.2 9.2 8.7 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Tox-REase-2 PF15646.1 ETO04526.1 - 3.2 7.6 6.2 6.6 6.6 3.9 1.9 1 1 0 1 1 1 0 Restriction endonuclease fold toxin 2 Kinesin-relat_1 PF12711.2 ETO04526.1 - 3.8 7.9 18.5 1.3 9.4 0.7 3.8 3 2 1 4 4 4 0 Kinesin motor TSC22 PF01166.13 ETO04526.1 - 8.5 6.4 13.6 9.8 6.2 0.3 4.0 3 2 1 4 4 4 0 TSC-22/dip/bun family WD40 PF00400.27 ETO04527.1 - 2e-22 78.2 12.6 4.4e-10 39.0 0.0 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO04527.1 - 3.4 8.0 6.1 1.2 9.3 0.1 3.1 4 0 0 4 4 4 0 Kelch motif WD40 PF00400.27 ETO04528.1 - 7.7e-157 504.3 54.2 5.5e-11 41.9 0.1 16.4 16 0 0 16 16 16 16 WD domain, G-beta repeat NACHT PF05729.7 ETO04528.1 - 1e-08 35.0 0.0 1.8e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Pentapeptide_4 PF13599.1 ETO04528.1 - 1.1e-05 25.0 0.5 3.1e-05 23.6 0.3 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETO04528.1 - 2.7e-05 23.3 0.7 5.6e-05 22.2 0.5 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 ETO04528.1 - 0.0011 18.8 0.1 0.004 17.0 0.1 2.0 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA_18 PF13238.1 ETO04528.1 - 0.0018 18.5 0.3 0.0018 18.5 0.2 5.3 6 1 0 6 6 6 1 AAA domain AAA_17 PF13207.1 ETO04528.1 - 0.031 15.0 5.1 0.045 14.5 0.0 3.8 3 0 0 3 3 3 0 AAA domain PD40 PF07676.7 ETO04528.1 - 0.061 13.0 12.3 17 5.1 0.0 6.2 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 ETO04529.1 - 2.9e-13 49.1 3.5 3.3e-09 36.2 0.0 3.1 2 1 1 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO04529.1 - 0.0052 14.9 0.3 0.0057 14.8 0.2 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 DUF4028 PF13220.1 ETO04529.1 - 0.61 9.7 3.0 2 8.1 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4028) Spc7 PF08317.6 ETO04531.1 - 0.005 15.5 6.8 0.0061 15.2 4.7 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF16 PF01519.11 ETO04531.1 - 0.013 15.7 8.8 0.017 15.3 5.9 1.3 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF848 PF05852.6 ETO04531.1 - 0.057 13.2 4.9 0.075 12.8 3.4 1.1 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Tropomyosin_1 PF12718.2 ETO04531.1 - 0.37 10.6 4.9 2.3 8.0 1.6 2.2 1 1 1 2 2 2 0 Tropomyosin like CATSPERB PF15149.1 ETO04531.1 - 0.76 7.9 6.8 0.88 7.6 4.7 1.1 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit beta protein family DUF2935 PF11155.3 ETO04531.1 - 1 9.4 5.0 1.7 8.7 3.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) Med4 PF10018.4 ETO04531.1 - 1.1 8.6 5.6 1.1 8.6 3.3 1.4 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Syntaxin-6_N PF09177.6 ETO04531.1 - 1.3 9.4 5.0 2 8.8 3.5 1.5 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF1951 PF09188.5 ETO04531.1 - 3.8 7.4 9.8 8.1 6.3 2.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1951) DUF4165 PF13752.1 ETO04532.1 - 0.085 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4165) DUF3605 PF12239.3 ETO04532.1 - 0.1 12.4 1.3 0.15 11.8 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3605) TTL PF03133.10 ETO04533.1 - 7e-05 21.8 0.0 9.6e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 ETO04533.1 - 0.034 12.9 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 YheC/D like ATP-grasp s48_45 PF07422.8 ETO04535.1 - 0.46 10.5 3.3 0.77 9.8 0.5 2.0 1 1 1 2 2 2 0 Sexual stage antigen s48/45 domain DUF972 PF06156.8 ETO04538.1 - 0.31 11.3 4.5 0.6 10.4 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF4636 PF15468.1 ETO04539.1 - 0.013 15.0 5.1 0.015 14.7 2.9 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4636) DUF4376 PF14301.1 ETO04539.1 - 0.055 13.6 0.7 0.087 12.9 0.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4376) WavE PF07507.6 ETO04539.1 - 0.15 10.9 3.1 0.17 10.7 2.1 1.0 1 0 0 1 1 1 0 WavE lipopolysaccharide synthesis DUF3713 PF12506.3 ETO04540.1 - 0.013 15.5 1.5 0.013 15.5 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) ZZ PF00569.12 ETO04540.1 - 0.013 14.9 1.0 0.029 13.9 0.7 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type DUF3783 PF12646.2 ETO04540.1 - 0.063 13.0 4.0 0.97 9.2 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3783) UpxZ PF06603.6 ETO04540.1 - 0.11 12.5 1.2 1.8 8.5 0.0 3.2 2 1 1 3 3 3 0 UpxZ family of transcription anti-terminator antagonists PP1_inhibitor PF05361.7 ETO04540.1 - 0.55 9.9 4.1 0.39 10.3 0.7 2.3 2 1 1 3 3 3 0 PKC-activated protein phosphatase-1 inhibitor DNA_pol_A_exo1 PF01612.15 ETO04541.1 - 6.7e-05 22.4 0.3 0.00022 20.7 0.0 2.0 2 0 0 2 2 2 1 3'-5' exonuclease PMC2NT PF08066.7 ETO04541.1 - 0.0024 18.1 0.4 0.016 15.4 0.3 2.3 2 0 0 2 2 2 1 PMC2NT (NUC016) domain Kelch_6 PF13964.1 ETO04542.1 - 4.7e-05 23.3 2.1 0.6 10.3 0.0 3.8 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.1 ETO04542.1 - 0.00057 19.5 3.0 1.2 8.9 0.0 4.0 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO04542.1 - 0.12 11.9 7.0 0.89 9.1 0.1 4.2 4 0 0 4 4 4 0 Kelch motif F-box-like PF12937.2 ETO04543.1 - 0.0029 17.2 0.0 0.0078 15.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETO04543.1 - 0.0055 16.3 0.0 0.015 14.8 0.0 1.8 1 0 0 1 1 1 1 F-box domain G6PD_N PF00479.17 ETO04543.1 - 0.027 14.7 0.1 0.54 10.4 0.0 2.2 2 0 0 2 2 2 0 Glucose-6-phosphate dehydrogenase, NAD binding domain CTP_transf_2 PF01467.21 ETO04544.1 - 1.5e-07 31.6 0.0 2.2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase UpxZ PF06603.6 ETO04545.1 - 0.0099 15.8 1.3 1.9 8.5 0.1 2.5 1 1 0 2 2 2 2 UpxZ family of transcription anti-terminator antagonists HSP90 PF00183.13 ETO04547.1 - 1.1e-241 802.9 32.4 1.1e-241 802.9 22.4 2.1 2 0 0 2 2 2 1 Hsp90 protein HATPase_c_3 PF13589.1 ETO04547.1 - 4.8e-11 42.4 0.1 4.8e-11 42.4 0.0 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 ETO04547.1 - 1.2e-10 41.1 0.0 2.1e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Not3 PF04065.10 ETO04548.1 - 9.1e-43 146.1 33.7 9.1e-43 146.1 23.4 4.1 3 2 1 4 4 4 2 Not1 N-terminal domain, CCR4-Not complex component DHC_N2 PF08393.8 ETO04550.1 - 1.2e-14 53.7 0.2 1.3e-14 53.5 0.2 1.1 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 Med18 PF09637.5 ETO04551.1 - 0.081 12.4 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Med18 protein Peptidase_S64 PF08192.6 ETO04552.1 - 0.068 11.4 20.5 0.075 11.3 14.2 1.2 1 0 0 1 1 1 0 Peptidase family S64 MIP-T3 PF10243.4 ETO04552.1 - 0.99 7.8 49.2 1.8 6.9 34.1 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Solute_trans_a PF03619.11 ETO04554.1 - 4.2e-38 131.2 7.1 5.6e-38 130.8 4.9 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Solute_trans_a PF03619.11 ETO04555.1 - 1.7e-29 103.0 2.5 1.8e-29 102.9 1.7 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha CotJB PF12652.2 ETO04555.1 - 0.061 13.4 0.0 0.098 12.7 0.0 1.3 1 0 0 1 1 1 0 CotJB protein Kazal_2 PF07648.10 ETO04555.1 - 0.18 11.7 1.4 0.24 11.3 0.2 1.8 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain Ribosomal_L18_c PF14204.1 ETO04559.1 - 4.1e-28 97.7 2.0 4.6e-28 97.6 1.4 1.1 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region DUF1476 PF07345.6 ETO04559.1 - 0.015 15.5 0.1 0.023 14.9 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1476) Ribosomal_L18_c PF14204.1 ETO04560.1 - 2.8e-16 59.8 5.8 7.4e-16 58.4 4.0 1.7 1 1 0 1 1 1 1 Ribosomal L18 C-terminal region EST1 PF10374.4 ETO04560.1 - 0.029 14.3 2.6 0.034 14.1 1.8 1.1 1 0 0 1 1 1 0 Telomerase activating protein Est1 Pox_H7 PF04787.7 ETO04560.1 - 0.074 12.8 2.9 0.094 12.5 2.0 1.1 1 0 0 1 1 1 0 Late protein H7 DUF968 PF06147.6 ETO04560.1 - 0.082 12.8 0.9 0.096 12.5 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF968) Syntaxin_2 PF14523.1 ETO04560.1 - 1.1 9.3 6.3 2 8.5 4.4 1.5 1 1 0 1 1 1 0 Syntaxin-like protein Ion_trans PF00520.26 ETO04561.1 - 5.8e-16 58.3 19.4 8.9e-16 57.7 13.5 1.3 1 0 0 1 1 1 1 Ion transport protein DUF2762 PF10960.3 ETO04561.1 - 0.019 14.6 0.4 0.083 12.6 0.3 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) DUF1664 PF07889.7 ETO04561.1 - 0.61 9.8 3.7 1 9.1 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Ion_trans PF00520.26 ETO04562.1 - 9.4e-08 31.5 23.2 5.6e-06 25.7 11.0 2.5 2 0 0 2 2 2 2 Ion transport protein EF-hand_1 PF00036.27 ETO04562.1 - 1.2e-06 27.3 0.1 0.00015 20.7 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 ETO04562.1 - 4.4e-06 26.1 0.1 0.0057 16.4 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 ETO04562.1 - 6.2e-06 26.2 1.3 9e-06 25.7 0.2 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 ETO04562.1 - 4.6e-05 22.5 0.1 0.00032 19.8 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 ETO04562.1 - 0.0052 16.3 0.9 0.044 13.4 0.2 2.4 1 1 1 2 2 2 2 EF-hand domain pair zf-LITAF-like PF10601.4 ETO04562.1 - 0.54 10.1 0.0 0.54 10.1 0.0 4.3 5 0 0 5 5 5 0 LITAF-like zinc ribbon domain DUF2306 PF10067.4 ETO04562.1 - 0.71 10.0 8.1 0.13 12.4 2.5 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2306) HemY_N PF07219.8 ETO04562.1 - 3.8 7.0 10.0 0.29 10.7 0.1 3.3 4 0 0 4 4 4 0 HemY protein N-terminus GST_C PF00043.20 ETO04563.1 - 3.3e-09 36.6 0.1 8.4e-09 35.3 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 ETO04563.1 - 4e-05 24.0 0.0 7.9e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETO04563.1 - 0.0086 15.9 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RraB PF06877.6 ETO04563.1 - 0.061 13.9 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 Regulator of ribonuclease activity B IMD PF08397.6 ETO04564.1 - 0.29 10.4 22.5 0.45 9.7 15.6 1.3 1 0 0 1 1 1 0 IRSp53/MIM homology domain RNA_pol_Rpb1_5 PF04998.12 ETO04564.1 - 2 7.6 8.8 2.4 7.3 6.1 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 YqfQ PF14181.1 ETO04564.1 - 2.5 8.1 18.9 5.1 7.1 13.1 1.4 1 0 0 1 1 1 0 YqfQ-like protein RIO1 PF01163.17 ETO04564.1 - 2.8 7.2 16.5 2 7.7 10.3 1.4 1 1 0 1 1 1 0 RIO1 family DDHD PF02862.12 ETO04564.1 - 3.4 7.4 9.0 3.7 7.2 6.2 1.2 1 0 0 1 1 1 0 DDHD domain PRP1_N PF06424.7 ETO04564.1 - 7 6.9 21.2 3.8 7.8 13.3 1.6 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal ubiquitin PF00240.18 ETO04565.1 - 1.7e-86 283.6 22.4 1.1e-27 95.1 0.5 5.1 3 1 2 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.3 ETO04565.1 - 9.4e-46 153.3 14.4 1.1e-16 60.3 0.2 4.4 3 1 2 5 5 5 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 ETO04565.1 - 1.6e-15 57.0 10.5 7.7e-05 22.8 0.2 5.1 3 2 1 4 4 4 4 Ubiquitin-like domain DUF2407 PF10302.4 ETO04565.1 - 2.1e-09 37.4 0.5 0.1 12.7 0.0 3.2 2 1 1 3 3 3 3 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 ETO04565.1 - 2.7e-08 33.6 0.4 0.056 13.3 0.0 4.2 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 ETO04565.1 - 5.8e-05 23.0 0.5 4.2 7.4 0.0 4.2 3 1 1 4 4 4 1 Protein of unknown function (DUF2870) PI3K_rbd PF00794.13 ETO04565.1 - 0.00082 19.2 4.9 3.8 7.4 0.0 3.7 3 1 0 3 3 3 2 PI3-kinase family, ras-binding domain UN_NPL4 PF11543.3 ETO04565.1 - 0.052 13.8 0.5 22 5.4 0.0 3.2 3 0 0 3 3 3 0 Nuclear pore localisation protein NPL4 TUG-UBL1 PF11470.3 ETO04565.1 - 0.13 12.1 7.6 4.7 7.2 0.0 3.9 3 1 1 4 4 4 0 GLUT4 regulating protein TUG DUF948 PF06103.6 ETO04565.1 - 3.8 7.4 7.7 12 5.7 1.5 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) GABP-alpha PF11620.3 ETO04565.1 - 5 7.1 7.6 5.1 7.1 0.5 3.0 3 1 0 3 3 3 0 GA-binding protein alpha chain Ank PF00023.25 ETO04566.1 - 6.4e-08 32.0 0.1 2.2e-07 30.3 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 ETO04566.1 - 3e-07 30.6 0.0 8.2e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO04566.1 - 3.5e-07 30.2 0.1 1e-06 28.7 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO04566.1 - 2.1e-06 27.4 1.0 8.3e-06 25.5 0.2 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 ETO04566.1 - 2.8e-06 27.7 0.2 1.4e-05 25.4 0.2 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) PBP1_TM PF14812.1 ETO04566.1 - 2.6 8.3 8.5 6.8 7.0 5.9 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF457 PF04307.9 ETO04567.1 - 0.0079 15.5 0.2 0.0094 15.2 0.2 1.2 1 0 0 1 1 1 1 Predicted membrane-bound metal-dependent hydrolase (DUF457) Pex16 PF08610.5 ETO04567.1 - 0.1 11.5 0.1 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) RGS PF00615.14 ETO04568.1 - 4.8e-06 26.6 1.6 2.8e-05 24.2 1.1 2.2 1 1 0 1 1 1 1 Regulator of G protein signaling domain WD40 PF00400.27 ETO04569.1 - 1.9e-16 59.2 3.9 2.8e-06 27.0 0.1 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat PD40 PF07676.7 ETO04569.1 - 5.8e-07 29.0 0.7 0.16 11.6 0.1 4.3 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat eIF2A PF08662.6 ETO04569.1 - 7.1e-06 25.8 1.0 2.3e-05 24.1 0.1 2.2 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 ETO04569.1 - 0.0021 17.2 0.4 7.7 5.5 0.0 3.1 1 1 2 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Kelch_6 PF13964.1 ETO04569.1 - 0.019 15.1 2.0 0.38 10.9 0.0 3.6 3 1 1 4 4 4 0 Kelch motif Proteasome_A_N PF10584.4 ETO04569.1 - 0.022 14.0 0.6 22 4.4 0.0 3.9 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Kelch_1 PF01344.20 ETO04569.1 - 0.023 14.2 0.2 0.049 13.1 0.2 1.6 1 0 0 1 1 1 0 Kelch motif Kelch_5 PF13854.1 ETO04569.1 - 0.074 13.0 0.4 0.24 11.4 0.3 1.9 1 0 0 1 1 1 0 Kelch motif GSH-S_ATP PF02955.11 ETO04569.1 - 0.1 11.7 1.3 0.48 9.5 0.5 2.0 2 0 0 2 2 2 0 Prokaryotic glutathione synthetase, ATP-grasp domain DUF3964 PF13107.1 ETO04569.1 - 0.14 12.4 2.7 0.18 12.0 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3964) WD40 PF00400.27 ETO04570.1 - 1.3e-51 170.7 30.2 6.1e-13 48.1 0.4 8.6 8 1 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO04570.1 - 1.9e-10 39.4 3.2 0.0038 15.4 0.1 5.0 2 1 2 5 5 5 4 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO04570.1 - 0.00049 20.4 2.2 0.001 19.4 0.6 2.3 2 0 0 2 2 2 1 TRAF-type zinc finger Actin PF00022.14 ETO04571.1 - 5.6e-91 304.8 0.0 6.3e-91 304.7 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 ETO04571.1 - 0.0055 15.3 0.1 0.0087 14.6 0.0 1.3 1 1 0 1 1 1 1 MreB/Mbl protein Thioredoxin_8 PF13905.1 ETO04572.1 - 0.086 12.9 0.7 0.086 12.9 0.5 1.6 2 0 0 2 2 2 0 Thioredoxin-like WD40 PF00400.27 ETO04574.1 - 4.6e-66 216.5 21.2 2.8e-11 42.8 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat PD40 PF07676.7 ETO04574.1 - 2.4e-07 30.2 9.4 0.71 9.6 0.0 5.5 6 0 0 6 6 6 4 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO04574.1 - 1.1e-06 27.2 1.2 0.004 15.4 0.0 3.0 1 1 2 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.3 ETO04574.1 - 0.00016 20.0 10.7 0.98 7.4 0.0 5.3 1 1 5 6 6 6 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO04574.1 - 0.00028 19.7 10.2 1.6 7.3 0.0 5.3 1 1 4 5 5 5 2 Nup133 N terminal like DPPIV_N PF00930.16 ETO04574.1 - 0.00034 19.3 0.3 0.024 13.2 0.0 3.2 2 1 0 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF3601 PF12208.3 ETO04574.1 - 0.00037 20.3 0.0 7.5 6.5 0.0 4.5 4 1 1 5 5 5 1 Domain of unknown function (DUF3601) Resistin PF06954.6 ETO04574.1 - 0.00061 20.0 0.3 31 4.9 0.0 4.8 2 1 2 5 5 5 0 Resistin DUF4221 PF13970.1 ETO04574.1 - 0.0028 17.0 0.5 1.9 7.7 0.1 3.3 1 1 0 3 3 3 1 Domain of unknown function (DUF4221) DUF1258 PF06869.7 ETO04574.1 - 0.0097 15.0 2.6 13 4.7 0.0 3.7 2 2 3 5 5 5 0 Protein of unknown function (DUF1258) Hira PF07569.6 ETO04574.1 - 0.024 13.8 2.4 7.2 5.7 0.0 3.5 2 1 3 5 5 5 0 TUP1-like enhancer of split Proteasome_A_N PF10584.4 ETO04574.1 - 0.55 9.6 0.0 0.55 9.6 0.0 5.0 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature RPEL PF02755.10 ETO04576.1 - 2.3 7.6 5.8 1.8 8.0 0.3 2.8 3 0 0 3 3 3 0 RPEL repeat WD40 PF00400.27 ETO04577.1 - 1.6e-55 183.1 19.5 1e-12 47.3 0.2 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO04577.1 - 5.8e-05 21.4 2.8 0.22 9.6 0.0 3.5 2 1 2 4 4 4 2 Nucleoporin Nup120/160 PD40 PF07676.7 ETO04577.1 - 0.0004 19.9 2.2 15 5.3 0.0 4.5 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 ETO04577.1 - 0.00042 19.4 0.7 0.72 8.9 0.0 4.2 2 1 3 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 ETO04577.1 - 0.0069 15.6 0.1 13 5.2 0.0 3.8 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature Cytochrom_D1 PF02239.11 ETO04577.1 - 0.013 13.8 0.0 0.51 8.5 0.0 2.9 1 1 2 3 3 3 0 Cytochrome D1 heme domain SGL PF08450.7 ETO04577.1 - 0.084 12.2 0.5 0.51 9.6 0.0 2.1 2 0 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region DUF759 PF05537.6 ETO04578.1 - 0.0063 15.3 0.3 0.0067 15.2 0.2 1.0 1 0 0 1 1 1 1 Borrelia burgdorferi protein of unknown function (DUF759) Hemagglutinin PF00509.13 ETO04578.1 - 0.041 12.0 0.1 0.052 11.7 0.1 1.1 1 0 0 1 1 1 0 Haemagglutinin RVP PF00077.15 ETO04579.1 - 0.067 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease UFC1 PF08694.6 ETO04579.1 - 0.11 12.0 2.1 14 5.1 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-fold modifier-conjugating enzyme 1 Asp_protease_2 PF13650.1 ETO04579.1 - 0.12 12.9 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.18 ETO04579.1 - 1.3 9.1 9.0 2.5 8.1 6.3 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF2356 PF10189.4 ETO04580.1 - 0.012 14.7 0.1 0.019 14.0 0.1 1.5 1 0 0 1 1 1 0 Conserved protein (DUF2356) YlbD_coat PF14071.1 ETO04580.1 - 0.07 13.1 0.6 0.14 12.1 0.4 1.5 1 0 0 1 1 1 0 Putative coat protein Sfi1_C PF10638.4 ETO04581.1 - 0.23 11.8 1.5 0.32 11.4 1.1 1.2 1 0 0 1 1 1 0 Spindle body associated protein C-terminus WD40 PF00400.27 ETO04585.1 - 3.4e-53 175.7 8.2 9.3e-13 47.5 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO04585.1 - 1.3e-08 33.5 2.0 0.0005 18.3 0.0 3.5 1 1 2 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO04585.1 - 2.7e-08 33.7 0.4 0.01 15.5 0.1 3.5 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO04585.1 - 1.5e-07 30.0 0.5 0.0021 16.3 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO04585.1 - 4.1e-07 29.6 0.0 1.4e-05 24.7 0.0 2.7 1 1 0 2 2 2 1 PQQ-like domain Nucleoporin_N PF08801.6 ETO04585.1 - 7.9e-05 21.5 5.3 1.1 7.8 0.5 4.0 2 2 2 4 4 4 3 Nup133 N terminal like Ricin_B_lectin PF00652.17 ETO04585.1 - 0.00061 19.8 0.3 2.6 8.0 0.1 3.4 1 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain PD40 PF07676.7 ETO04585.1 - 0.013 15.1 4.2 6 6.6 0.0 5.1 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat CRT10 PF08728.5 ETO04585.1 - 0.019 12.9 0.6 1.6 6.6 0.1 2.2 1 1 1 2 2 2 0 CRT10 Coatomer_WDAD PF04053.9 ETO04585.1 - 0.027 13.2 0.6 0.15 10.7 0.1 2.2 1 1 1 2 2 2 0 Coatomer WD associated region DUF2850 PF11012.3 ETO04585.1 - 0.037 14.1 0.0 0.082 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2850) Nbas_N PF15492.1 ETO04585.1 - 0.039 13.0 0.2 4.6 6.2 0.0 3.2 1 1 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Me-amine-dh_H PF06433.6 ETO04585.1 - 0.056 12.0 0.0 0.83 8.2 0.0 2.2 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) Monellin PF09200.5 ETO04587.1 - 0.19 11.3 0.7 0.46 10.1 0.0 2.1 2 0 0 2 2 2 0 Monellin Actin PF00022.14 ETO04588.1 - 3.1e-07 29.1 0.0 3.1e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Actin SH PF01445.12 ETO04588.1 - 0.12 12.0 0.8 0.22 11.1 0.5 1.4 1 0 0 1 1 1 0 Viral small hydrophobic protein DUF4209 PF13910.1 ETO04589.1 - 3.5e-13 49.4 1.4 2.6e-11 43.4 0.1 3.2 2 1 0 2 2 2 2 Domain of unknown function (DUF4209) PHO4 PF01384.15 ETO04590.1 - 0.038 12.6 0.0 0.039 12.6 0.0 1.2 1 0 0 1 1 1 0 Phosphate transporter family SLBP_RNA_bind PF15247.1 ETO04591.1 - 3.5e-16 58.7 4.9 1.3e-15 56.9 3.3 2.0 1 1 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain Chromo PF00385.19 ETO04591.1 - 0.25 11.0 2.7 1.1 8.9 0.2 2.5 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Ribosomal_S4 PF00163.14 ETO04591.1 - 1.8 8.9 8.1 0.18 12.2 1.2 2.2 1 1 1 2 2 2 0 Ribosomal protein S4/S9 N-terminal domain zf-DHHC PF01529.15 ETO04592.1 - 2.3e-31 108.5 12.7 2.3e-31 108.5 8.8 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase 7TMR-DISM_7TM PF07695.6 ETO04592.1 - 0.31 10.6 9.6 1.5 8.4 4.9 2.7 2 1 0 2 2 2 0 7TM diverse intracellular signalling Claudin_3 PF06653.6 ETO04592.1 - 0.58 9.8 7.4 1 9.0 0.1 2.1 1 1 1 2 2 2 0 Tight junction protein, Claudin-like OKR_DC_1_N PF03709.10 ETO04593.1 - 0.015 15.3 0.1 0.036 14.1 0.1 1.6 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain DUF1955 PF09205.5 ETO04594.1 - 0.025 14.0 4.6 1.4 8.4 0.2 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF1955) WD40 PF00400.27 ETO04595.1 - 5.5e-55 181.3 12.5 2.5e-11 42.9 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO04595.1 - 1.4e-08 34.6 0.7 0.0036 17.0 0.1 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 ETO04595.1 - 5.7e-05 22.0 2.7 0.16 10.7 0.8 2.4 1 1 1 2 2 2 2 Nup133 N terminal like Hira PF07569.6 ETO04595.1 - 7.1e-05 22.1 0.2 0.36 10.0 0.0 3.2 3 0 0 3 3 3 2 TUP1-like enhancer of split PQQ_2 PF13360.1 ETO04595.1 - 0.0001 21.8 0.2 0.00067 19.1 0.1 2.1 2 0 0 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO04595.1 - 0.00019 19.8 1.1 5.8 5.1 0.2 3.6 2 1 2 4 4 4 4 Cytochrome D1 heme domain Nup160 PF11715.3 ETO04595.1 - 0.0039 15.4 3.2 0.87 7.6 0.0 4.1 2 2 1 4 4 4 1 Nucleoporin Nup120/160 Ricin_B_lectin PF00652.17 ETO04595.1 - 0.039 13.9 0.8 12 5.9 0.0 2.8 2 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain PD40 PF07676.7 ETO04595.1 - 0.062 12.9 2.1 8 6.2 0.0 4.3 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat NYD-SP28_assoc PF14775.1 ETO04595.1 - 0.11 12.1 0.6 70 3.2 0.0 4.1 4 0 0 4 4 4 0 Sperm tail C-terminal domain bZIP_1 PF00170.16 ETO04596.1 - 0.029 14.3 1.9 0.036 14.0 0.4 1.7 2 0 0 2 2 2 0 bZIP transcription factor DUF4254 PF14063.1 ETO04596.1 - 0.068 12.7 1.0 0.13 11.8 0.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4254) Apolipo_F PF15148.1 ETO04596.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.3 1 1 0 1 1 1 0 Apolipoprotein F NIF PF03031.13 ETO04597.1 - 1.1e-25 90.1 0.8 1.1e-25 90.1 0.6 1.5 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase FimP PF09766.4 ETO04597.1 - 0.0045 16.1 10.7 0.0054 15.8 7.4 1.1 1 0 0 1 1 1 1 Fms-interacting protein DUF3121 PF11319.3 ETO04597.1 - 0.05 13.1 4.0 0.063 12.7 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3121) DDRGK PF09756.4 ETO04597.1 - 0.058 12.7 16.3 0.078 12.3 11.3 1.3 1 0 0 1 1 1 0 DDRGK domain DUF4207 PF13904.1 ETO04597.1 - 0.4 10.0 20.4 0.56 9.5 14.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) DUF4355 PF14265.1 ETO04597.1 - 0.49 10.3 16.5 0.84 9.6 11.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) CAF-1_p150 PF11600.3 ETO04597.1 - 0.54 9.5 25.5 0.79 9.0 17.7 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Peptidase_C58 PF03543.9 ETO04597.1 - 0.96 8.9 6.8 1.3 8.4 4.7 1.3 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen Gastrin PF00918.12 ETO04597.1 - 1.2 9.9 12.4 2.3 9.0 8.6 1.4 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Apc1 PF12859.2 ETO04597.1 - 1.4 9.1 4.9 4.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 Ndc1_Nup PF09531.5 ETO04597.1 - 2.5 6.4 8.0 3.1 6.0 5.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4175 PF13779.1 ETO04597.1 - 3.8 5.0 17.2 4.7 4.7 11.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) G-alpha PF00503.15 ETO04597.1 - 4.1 5.9 15.0 8.8 4.8 0.1 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Rep_fac_C PF08542.6 ETO04598.1 - 0.021 14.8 1.3 2.8 7.9 0.0 2.2 2 0 0 2 2 2 0 Replication factor C C-terminal domain Corona_NS1 PF06145.6 ETO04598.1 - 0.16 11.2 0.4 0.32 10.3 0.3 1.4 1 0 0 1 1 1 0 Coronavirus nonstructural protein NS1 SNAPc19 PF15497.1 ETO04598.1 - 0.36 11.0 12.0 0.98 9.6 7.4 2.4 1 1 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Ly49 PF08391.5 ETO04598.1 - 4.3 7.4 7.4 0.94 9.6 0.3 2.3 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region DUF2296 PF10058.4 ETO04599.1 - 0.11 12.3 3.8 1.2 8.9 0.1 3.1 3 0 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) Kelch_1 PF01344.20 ETO04600.1 - 0.00016 21.1 1.9 0.0021 17.5 0.1 3.2 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO04600.1 - 0.0099 15.6 0.5 0.96 9.2 0.0 3.3 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO04600.1 - 0.025 14.7 0.6 7.8 6.8 0.0 3.5 3 0 0 3 3 3 0 Kelch motif TPR_12 PF13424.1 ETO04601.1 - 5.6e-88 288.9 22.4 3.2e-19 68.6 0.1 6.2 3 3 3 6 6 6 6 Tetratricopeptide repeat TPR_11 PF13414.1 ETO04601.1 - 1e-48 162.8 50.9 3.1e-11 42.7 0.1 6.1 1 1 7 8 8 8 8 TPR repeat TPR_10 PF13374.1 ETO04601.1 - 4.5e-39 131.2 0.0 1.4e-06 28.0 0.0 9.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETO04601.1 - 5e-38 125.9 31.9 2.8e-06 26.8 0.8 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_1 PF00515.23 ETO04601.1 - 8.4e-37 123.2 48.5 2.1e-06 27.0 0.5 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_7 PF13176.1 ETO04601.1 - 6.2e-32 106.8 9.8 9.8e-06 25.0 0.0 8.5 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.1 ETO04601.1 - 1.9e-29 99.2 45.2 0.00022 20.7 0.5 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_16 PF13432.1 ETO04601.1 - 1.1e-16 60.9 0.0 0.0047 17.5 0.0 5.8 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO04601.1 - 4.2e-14 51.7 0.0 0.54 11.0 0.0 8.1 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO04601.1 - 2.6e-12 45.9 7.4 2.9 8.3 0.0 10.2 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO04601.1 - 7.8e-12 44.8 12.0 0.51 10.9 0.0 8.8 9 0 0 9 9 9 3 Tetratricopeptide repeat Apc3 PF12895.2 ETO04601.1 - 4.1e-07 30.0 25.4 0.044 13.9 5.7 5.2 1 1 3 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO04601.1 - 4.9e-07 29.9 5.7 0.5 10.7 0.0 6.8 2 2 4 7 7 7 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO04601.1 - 3.6e-05 22.8 1.4 2.3 7.5 0.0 5.6 6 0 0 6 6 6 1 SHNi-TPR TPR_21 PF09976.4 ETO04601.1 - 0.00016 21.6 3.4 0.95 9.3 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat MIT PF04212.13 ETO04601.1 - 0.00073 19.3 22.0 0.63 9.9 0.3 8.0 8 1 0 8 8 8 1 MIT (microtubule interacting and transport) domain DUF3856 PF12968.2 ETO04601.1 - 0.0033 17.2 3.0 3.7 7.3 0.0 4.2 3 1 0 4 4 4 1 Domain of Unknown Function (DUF3856) PPR PF01535.15 ETO04601.1 - 0.76 9.8 9.5 26 5.0 0.0 5.6 6 0 0 6 6 5 0 PPR repeat Sel1 PF08238.7 ETO04601.1 - 7 7.4 19.2 20 5.9 0.1 6.9 8 0 0 8 8 8 0 Sel1 repeat Pkinase PF00069.20 ETO04605.1 - 5.2e-63 212.6 0.2 7.1e-63 212.1 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO04605.1 - 2.5e-25 89.0 2.1 5.3e-13 48.6 1.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 ETO04605.1 - 0.054 12.4 0.1 0.12 11.2 0.0 1.7 1 1 0 1 1 1 0 Kinase-like Utp14 PF04615.8 ETO04606.1 - 0.077 11.1 31.5 0.17 10.0 21.8 1.6 1 0 0 1 1 1 0 Utp14 protein Arm PF00514.18 ETO04607.1 - 2e-05 24.1 0.1 4.4 7.2 0.1 5.1 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Nipped-B_C PF12830.2 ETO04607.1 - 0.009 15.6 0.6 3.5 7.2 0.0 3.2 2 1 1 3 3 3 2 Sister chromatid cohesion C-terminus Arm PF00514.18 ETO04608.1 - 0.0023 17.7 2.9 2.5 8.0 0.0 4.3 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 ETO04608.1 - 0.041 14.1 2.5 0.12 12.6 1.5 2.0 1 1 0 1 1 1 0 HEAT repeats UPF0147 PF03685.8 ETO04608.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) EF-hand_6 PF13405.1 ETO04610.1 - 0.015 15.1 0.1 0.053 13.4 0.1 2.0 1 0 0 1 1 1 0 EF-hand domain UPF0193 PF05250.6 ETO04611.1 - 0.00013 21.5 8.0 0.00018 21.1 5.3 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0193) AAA_23 PF13476.1 ETO04611.1 - 0.1 12.9 16.9 0.13 12.5 11.7 1.2 1 0 0 1 1 1 0 AAA domain NOP5NT PF08156.8 ETO04611.1 - 0.13 12.3 0.5 0.46 10.6 0.1 2.1 2 0 0 2 2 2 0 NOP5NT (NUC127) domain DUF2120 PF09893.4 ETO04611.1 - 0.15 12.0 5.4 0.066 13.1 1.5 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) DUF3090 PF11290.3 ETO04611.1 - 0.16 11.4 0.4 0.34 10.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) PAS_9 PF13426.1 ETO04611.1 - 0.3 11.4 1.9 0.77 10.1 0.3 2.3 3 0 0 3 3 3 0 PAS domain POX PF07526.6 ETO04611.1 - 4.7 7.4 8.9 0.6 10.3 2.6 1.9 1 1 1 2 2 2 0 Associated with HOX DUF2203 PF09969.4 ETO04611.1 - 4.9 7.3 6.9 1.5 9.0 1.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Glyco_hydro_2_N PF02837.13 ETO04612.1 - 1.3e-05 24.8 0.0 0.047 13.2 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 2, sugar binding domain Silic_transp PF03842.8 ETO04613.1 - 0.15 10.1 2.1 0.17 9.9 1.5 1.1 1 0 0 1 1 1 0 Silicon transporter Presenilin PF01080.12 ETO04613.1 - 4.6 5.9 7.9 5.2 5.7 5.4 1.1 1 0 0 1 1 1 0 Presenilin PA26 PF04636.8 ETO04613.1 - 7.9 5.0 9.0 8.7 4.9 6.2 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CathepsinC_exc PF08773.6 ETO04614.1 - 0.15 12.2 1.3 0.3 11.2 0.1 1.8 1 1 1 2 2 2 0 Cathepsin C exclusion domain HEAT_2 PF13646.1 ETO04615.1 - 0.0071 16.6 0.0 0.0089 16.2 0.0 1.2 1 0 0 1 1 1 1 HEAT repeats Vfa1 PF08432.5 ETO04616.1 - 0.023 14.7 8.7 0.028 14.4 6.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Serinc PF03348.10 ETO04616.1 - 0.032 12.9 0.2 0.035 12.8 0.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) TTKRSYEDQ PF10212.4 ETO04616.1 - 0.073 11.9 6.2 0.089 11.7 4.3 1.0 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Fmp27_WPPW PF10359.4 ETO04616.1 - 0.082 11.3 7.1 0.095 11.1 4.9 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain CARD PF00619.16 ETO04616.1 - 0.088 12.6 5.5 0.17 11.7 3.8 1.5 1 1 0 1 1 1 0 Caspase recruitment domain DUF2407 PF10302.4 ETO04616.1 - 0.32 11.2 2.8 0.47 10.6 2.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF342 PF03961.8 ETO04616.1 - 0.57 8.5 14.5 0.68 8.2 10.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4252 PF14060.1 ETO04616.1 - 0.98 8.9 8.5 1.3 8.5 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) FemAB PF02388.11 ETO04616.1 - 1.5 7.4 8.8 1.7 7.2 6.1 1.0 1 0 0 1 1 1 0 FemAB family IncA PF04156.9 ETO04616.1 - 7.9 6.0 10.5 11 5.5 7.3 1.3 1 0 0 1 1 1 0 IncA protein Cytotoxic PF09000.5 ETO04617.1 - 0.012 15.6 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Cytotoxic DUF137 PF02006.11 ETO04617.1 - 0.11 11.8 0.1 0.26 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF137 zf-HC5HC2H PF13771.1 ETO04617.1 - 0.12 12.5 3.7 0.23 11.6 2.6 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF4116 PF13475.1 ETO04618.1 - 0.16 11.4 2.6 0.27 10.7 1.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4116) DUF2407 PF10302.4 ETO04620.1 - 0.24 11.6 0.1 0.24 11.6 0.1 4.4 2 1 0 2 2 2 0 DUF2407 ubiquitin-like domain HSP70 PF00012.15 ETO04621.1 - 2.5e-35 121.5 2.8 8.5e-21 73.4 0.0 3.1 1 1 2 3 3 3 3 Hsp70 protein MreB_Mbl PF06723.8 ETO04621.1 - 0.004 15.8 0.0 0.0054 15.3 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein WD40 PF00400.27 ETO04622.1 - 1.2e-156 503.6 49.4 2.5e-12 46.1 0.2 16.2 16 0 0 16 16 16 16 WD domain, G-beta repeat Nup160 PF11715.3 ETO04622.1 - 2.4e-17 62.2 21.1 0.064 11.3 0.0 12.3 1 1 7 11 11 11 10 Nucleoporin Nup120/160 PD40 PF07676.7 ETO04622.1 - 2.5e-08 33.3 19.3 0.69 9.6 0.0 9.5 10 0 0 10 10 10 3 WD40-like Beta Propeller Repeat Pentapeptide PF00805.17 ETO04622.1 - 4.4e-06 25.8 0.2 1.3e-05 24.3 0.1 1.9 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Cytochrom_D1 PF02239.11 ETO04622.1 - 4.7e-06 25.1 10.8 0.013 13.8 0.1 5.8 3 1 4 8 8 8 2 Cytochrome D1 heme domain Pentapeptide_4 PF13599.1 ETO04622.1 - 2.3e-05 24.0 0.5 5.6e-05 22.8 0.3 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 ETO04622.1 - 7.6e-05 22.5 0.5 0.00027 20.7 0.3 2.0 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) PLD_C PF12357.3 ETO04622.1 - 0.0049 16.3 0.3 56 3.3 0.0 6.8 10 1 1 11 11 11 0 Phospholipase D C terminal Resistin PF06954.6 ETO04622.1 - 0.005 17.0 0.0 37 4.6 0.0 5.7 7 0 0 7 7 6 0 Resistin DUF1625 PF07787.7 ETO04622.1 - 0.014 14.6 0.0 12 5.0 0.0 4.8 5 1 0 6 6 6 0 Protein of unknown function (DUF1625) F420_ligase PF01996.11 ETO04622.1 - 0.032 13.3 0.0 35 3.3 0.0 4.0 4 1 0 4 4 4 0 F420-0:Gamma-glutamyl ligase YqaJ PF09588.5 ETO04622.1 - 1 9.2 3.9 1.6 8.6 0.1 2.9 2 2 0 2 2 2 0 YqaJ-like viral recombinase domain Pro_isomerase PF00160.16 ETO04625.1 - 0.048 13.8 1.0 0.057 13.6 0.7 1.0 1 0 0 1 1 1 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RWD PF05773.17 ETO04626.1 - 1.8e-07 31.0 1.3 3e-07 30.3 0.2 1.9 2 1 0 2 2 2 1 RWD domain DUF1115 PF06544.7 ETO04626.1 - 0.00017 21.2 0.0 0.00037 20.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) DUF167 PF02594.11 ETO04627.1 - 1.2e-23 82.8 0.2 2e-23 82.1 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 MTTB PF06253.6 ETO04627.1 - 0.061 11.0 0.2 0.083 10.6 0.2 1.2 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) Pkinase PF00069.20 ETO04628.1 - 1.8e-23 83.0 0.6 2.1e-23 82.8 0.4 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO04628.1 - 5.3e-18 65.0 0.2 5.5e-18 64.9 0.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.27 ETO04629.1 - 1.6e-05 24.6 0.0 0.00013 21.6 0.0 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat Yippee-Mis18 PF03226.9 ETO04629.1 - 3.4 7.7 7.0 2.6 8.1 3.6 1.8 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HSP70 PF00012.15 ETO04630.1 - 0.051 11.4 0.4 0.063 11.1 0.3 1.2 1 0 0 1 1 1 0 Hsp70 protein DUF63 PF01889.12 ETO04632.1 - 0.11 12.5 0.4 0.16 11.9 0.3 1.3 1 1 0 1 1 1 0 Membrane protein of unknown function DUF63 DivIC PF04977.10 ETO04633.1 - 0.0037 16.7 2.9 0.0037 16.7 2.0 4.0 4 1 0 4 4 4 1 Septum formation initiator DUF1644 PF07800.7 ETO04633.1 - 0.0072 16.1 10.1 0.0072 16.1 7.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1644) DUF948 PF06103.6 ETO04633.1 - 0.075 12.9 0.6 0.075 12.9 0.4 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 ETO04633.1 - 0.17 11.4 18.1 1.1 8.8 12.5 2.3 1 1 0 1 1 1 0 IncA protein zf-HC5HC2H PF13771.1 ETO04633.1 - 0.98 9.6 6.1 3.8 7.7 1.5 2.9 1 1 1 2 2 2 0 PHD-like zinc-binding domain DUF641 PF04859.7 ETO04633.1 - 1.4 8.6 9.4 0.29 10.8 2.2 2.4 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) TSC22 PF01166.13 ETO04633.1 - 2.8 7.9 11.4 6.2 6.8 1.7 3.9 3 1 0 3 3 3 0 TSC-22/dip/bun family Prefoldin PF02996.12 ETO04633.1 - 3.1 7.4 16.9 0.61 9.7 5.2 2.6 2 1 0 2 2 2 0 Prefoldin subunit SlyX PF04102.7 ETO04633.1 - 6.5 7.2 15.2 3.7 7.9 3.7 2.7 2 0 0 2 2 2 0 SlyX FliD_N PF02465.13 ETO04634.1 - 0.02 15.2 6.5 0.043 14.1 1.7 2.3 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus zf-C3HC4_2 PF13923.1 ETO04634.1 - 0.031 14.2 3.1 0.25 11.4 2.2 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO04634.1 - 0.069 13.0 2.3 0.2 11.5 1.6 1.8 1 1 0 1 1 1 0 Ring finger domain DUF1664 PF07889.7 ETO04634.1 - 0.33 10.7 4.5 0.52 10.1 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF1644 PF07800.7 ETO04634.1 - 0.42 10.4 17.4 0.45 10.3 9.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) zf-BED PF02892.10 ETO04634.1 - 1.1 9.0 5.0 0.63 9.8 1.1 2.4 3 0 0 3 3 3 0 BED zinc finger FlxA PF14282.1 ETO04634.1 - 6.6 6.7 19.8 0.33 10.9 8.9 2.5 3 1 0 3 3 3 0 FlxA-like protein DUF4446 PF14584.1 ETO04635.1 - 0.35 10.6 2.0 0.57 9.9 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF2951 PF11166.3 ETO04635.1 - 7.3 6.5 8.5 2.4 8.0 3.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) SNAPc19 PF15497.1 ETO04637.1 - 0.44 10.7 5.0 0.49 10.6 3.5 1.1 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 ubiquitin PF00240.18 ETO04638.1 - 1.1e-16 60.0 0.0 1.9e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 ETO04638.1 - 7.6e-09 35.1 0.0 1.2e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 ETO04638.1 - 3.6e-05 23.9 0.0 7.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain DUF4594 PF15266.1 ETO04639.1 - 0.39 10.8 7.5 0.11 12.6 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4594) Leo1 PF04004.8 ETO04639.1 - 1.1 8.9 10.1 0.11 12.1 0.3 2.3 2 1 1 3 3 3 0 Leo1-like protein COPR5 PF15340.1 ETO04639.1 - 1.2 9.5 4.4 0.61 10.4 0.2 2.0 2 0 0 2 2 2 0 Cooperator of PRMT5 family Methyltransf_28 PF02636.12 ETO04640.1 - 6.2e-32 110.9 0.0 8e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase WD40 PF00400.27 ETO04641.1 - 6.3e-78 254.1 9.3 8.1e-12 44.5 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat PD40 PF07676.7 ETO04641.1 - 2.4e-08 33.4 4.7 1.6 8.4 0.0 7.0 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO04641.1 - 6.5e-08 31.7 3.8 0.1 11.3 0.0 4.3 1 1 3 4 4 4 4 Nup133 N terminal like Nup160 PF11715.3 ETO04641.1 - 8.1e-08 30.8 0.0 0.053 11.6 0.0 4.2 1 1 2 3 3 3 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO04641.1 - 8.6e-06 25.3 0.0 0.00027 20.4 0.0 2.7 1 1 2 3 3 3 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO04641.1 - 6.4e-05 21.4 0.0 0.0042 15.4 0.0 2.8 2 1 1 3 3 3 1 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO04641.1 - 0.00015 20.9 2.6 0.13 11.3 0.0 4.2 2 2 3 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Hira PF07569.6 ETO04641.1 - 0.0036 16.5 0.1 9.4 5.3 0.0 4.1 2 1 2 4 4 4 1 TUP1-like enhancer of split NHL PF01436.16 ETO04641.1 - 0.036 14.0 0.0 0.46 10.5 0.0 2.7 3 0 0 3 3 3 0 NHL repeat DUF3732 PF12532.3 ETO04641.1 - 0.042 13.3 0.1 16 4.9 0.0 3.7 1 1 3 4 4 4 0 Protein of unknown function (DUF3732) DUF2335 PF10097.4 ETO04641.1 - 0.086 12.4 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) Kelch_1 PF01344.20 ETO04642.1 - 3.7e-06 26.3 0.5 3.7e-06 26.3 0.3 4.2 6 0 0 6 6 6 1 Kelch motif Kelch_6 PF13964.1 ETO04642.1 - 0.00037 20.5 6.6 0.022 14.9 0.4 4.2 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.1 ETO04642.1 - 0.00057 19.5 0.1 0.078 12.7 0.0 2.9 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO04642.1 - 0.0011 18.9 0.2 0.099 12.6 0.2 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO04642.1 - 0.06 13.1 1.1 0.77 9.6 0.2 3.1 4 0 0 4 4 4 0 Kelch motif Kelch_3 PF13415.1 ETO04642.1 - 0.078 13.1 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 Galactose oxidase, central domain Utp14 PF04615.8 ETO04642.1 - 7.4 4.6 51.2 11 4.0 35.5 1.1 1 0 0 1 1 1 0 Utp14 protein Peptidase_C14 PF00656.17 ETO04643.1 - 9.3e-09 35.3 1.9 9.3e-09 35.3 1.3 2.0 2 1 0 2 2 2 1 Caspase domain DNA_pol3_delta2 PF13177.1 ETO04643.1 - 0.014 15.1 0.9 0.014 15.1 0.6 2.6 1 1 1 2 2 2 0 DNA polymerase III, delta subunit Suc_Fer-like PF06999.7 ETO04643.1 - 0.042 13.8 2.0 0.086 12.8 1.4 1.4 1 0 0 1 1 1 0 Sucrase/ferredoxin-like Polysacc_syn_2C PF08485.5 ETO04643.1 - 2.1 7.9 6.2 7.3 6.1 0.1 3.4 4 0 0 4 4 4 0 Polysaccharide biosynthesis protein C-terminal PUB PF09409.5 ETO04646.1 - 0.0051 16.5 2.7 0.64 9.8 0.2 2.6 3 0 0 3 3 3 2 PUB domain HSBP1 PF06825.7 ETO04646.1 - 0.14 11.7 1.9 4.9 6.8 0.1 3.0 3 0 0 3 3 3 0 Heat shock factor binding protein 1 WD40 PF00400.27 ETO04647.1 - 6.5e-17 60.7 1.8 1.9e-06 27.4 0.1 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO04647.1 - 0.0035 15.5 0.2 0.18 9.8 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Hira PF07569.6 ETO04647.1 - 0.02 14.0 0.3 1.1 8.4 0.0 2.3 1 1 1 2 2 2 0 TUP1-like enhancer of split Nucleoporin_N PF08801.6 ETO04647.1 - 0.024 13.3 0.7 2.7 6.6 0.0 2.2 1 1 1 2 2 2 0 Nup133 N terminal like Ricin_B_lectin PF00652.17 ETO04647.1 - 0.029 14.4 0.6 0.097 12.7 0.1 1.7 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain Pup_ligase PF03136.10 ETO04649.1 - 0.03 12.9 0.6 0.034 12.7 0.4 1.0 1 0 0 1 1 1 0 Pup-ligase protein Kelch_6 PF13964.1 ETO04652.1 - 2.2e-06 27.5 2.4 0.0031 17.5 0.1 4.1 3 1 1 4 4 4 1 Kelch motif Kelch_1 PF01344.20 ETO04652.1 - 2.3e-05 23.8 2.1 0.0034 16.8 0.3 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO04652.1 - 0.00049 19.7 2.3 0.045 13.5 0.4 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 ETO04652.1 - 0.0016 18.3 0.8 0.079 12.9 0.5 3.1 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 ETO04652.1 - 0.0023 18.0 0.1 0.036 14.2 0.0 2.8 2 0 0 2 2 2 1 Galactose oxidase, central domain DUF4231 PF14015.1 ETO04653.1 - 0.04 13.9 0.1 0.04 13.9 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Fe-S_biosyn PF01521.15 ETO04654.1 - 3.6e-12 46.2 1.5 5.2e-12 45.7 1.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF1573 PF07610.6 ETO04654.1 - 0.08 12.5 0.7 2.6 7.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1573) CopC PF04234.7 ETO04655.1 - 0.016 15.8 0.3 0.016 15.8 0.2 2.0 2 0 0 2 2 2 0 CopC domain Kelch_6 PF13964.1 ETO04658.1 - 0.0013 18.8 0.2 0.088 13.0 0.0 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.20 ETO04658.1 - 0.89 9.1 3.1 2.6 7.6 0.1 2.6 3 0 0 3 3 3 0 Kelch motif SOBP PF15279.1 ETO04659.1 - 0.59 10.4 14.5 0.94 9.7 10.0 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Fer4 PF00037.22 ETO04660.1 - 7.3e-11 41.1 18.7 2.4e-06 26.8 2.5 3.2 3 0 0 3 3 3 3 4Fe-4S binding domain Fer4_7 PF12838.2 ETO04660.1 - 1.7e-10 41.0 8.9 1.2e-09 38.3 5.8 2.1 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 ETO04660.1 - 1.7e-07 30.9 6.7 1.7e-07 30.9 4.7 1.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 ETO04660.1 - 6.8e-07 29.9 6.5 0.00031 21.4 4.0 2.4 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_9 PF13187.1 ETO04660.1 - 3e-06 27.4 8.2 3.4e-05 24.0 4.9 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 ETO04660.1 - 1.8e-05 24.3 16.3 0.00049 19.8 2.8 2.8 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_21 PF14697.1 ETO04660.1 - 2e-05 24.3 8.6 6.2e-05 22.7 0.3 2.7 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_17 PF13534.1 ETO04660.1 - 7.2e-05 23.0 4.2 0.083 13.2 5.5 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.2 ETO04660.1 - 7.2e-05 22.4 20.3 0.00044 19.9 3.5 3.3 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_8 PF13183.1 ETO04660.1 - 0.00015 21.7 7.7 0.0021 18.0 5.8 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.2 ETO04660.1 - 0.00056 20.0 2.4 0.00056 20.0 1.7 2.7 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_15 PF13459.1 ETO04660.1 - 0.0089 16.5 12.4 0.34 11.5 1.1 3.2 3 0 0 3 3 3 2 4Fe-4S single cluster domain Fer4_18 PF13746.1 ETO04660.1 - 0.0097 16.3 0.9 0.0097 16.3 0.6 3.2 2 2 1 3 3 3 1 4Fe-4S dicluster domain Fer4_13 PF13370.1 ETO04660.1 - 0.026 14.9 12.5 0.12 12.7 2.2 3.1 3 0 0 3 3 3 0 4Fe-4S single cluster domain c-SKI_SMAD_bind PF08782.5 ETO04660.1 - 0.13 12.4 3.3 0.44 10.6 0.1 2.5 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Claudin_2 PF13903.1 ETO04661.1 - 0.0086 15.7 0.8 0.012 15.2 0.4 1.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction CD20 PF04103.10 ETO04661.1 - 0.086 12.7 1.0 0.19 11.6 0.1 1.8 2 0 0 2 2 2 0 CD20-like family AdoHcyase_NAD PF00670.16 ETO04662.1 - 2.9e-74 248.3 5.9 3.7e-74 247.9 4.1 1.1 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AdoHcyase PF05221.12 ETO04662.1 - 2.8e-39 134.6 0.0 3.4e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase 2-Hacid_dh_C PF02826.14 ETO04662.1 - 3.1e-08 32.9 0.4 5e-08 32.2 0.3 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 ETO04662.1 - 4e-06 26.3 0.3 6.2e-06 25.6 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 ETO04662.1 - 3.3e-05 23.8 1.1 0.00035 20.5 0.8 2.3 1 1 0 1 1 1 1 TrkA-N domain THF_DHG_CYH_C PF02882.14 ETO04662.1 - 0.0001 21.3 3.5 0.00085 18.4 2.4 2.1 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.1 ETO04662.1 - 0.00059 20.0 0.4 0.0011 19.1 0.3 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 ETO04662.1 - 0.00092 19.3 0.9 0.0022 18.1 0.6 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 ETO04662.1 - 0.0096 15.5 1.1 0.029 14.0 0.2 1.9 1 1 1 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 ETO04662.1 - 0.012 15.2 0.8 0.02 14.4 0.3 1.5 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Malic_M PF03949.10 ETO04662.1 - 1.6 8.2 4.2 11 5.4 0.1 2.2 1 1 0 2 2 2 0 Malic enzyme, NAD binding domain Arch_ATPase PF01637.13 ETO04663.1 - 7.1e-06 25.8 8.9 0.00018 21.2 6.2 2.2 1 1 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 ETO04663.1 - 9.2e-06 25.7 0.0 1.6e-05 25.0 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 ETO04663.1 - 2.3e-05 24.5 0.6 0.0011 19.1 0.4 2.2 1 1 0 1 1 1 1 AAA domain DUF87 PF01935.12 ETO04663.1 - 0.002 17.9 4.5 0.043 13.6 0.0 2.2 1 1 1 2 2 2 1 Domain of unknown function DUF87 BAR_2 PF10455.4 ETO04663.1 - 0.0037 16.2 1.0 0.0041 16.0 0.7 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking AAA_24 PF13479.1 ETO04663.1 - 0.0045 16.6 0.1 0.84 9.1 0.2 2.3 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 ETO04663.1 - 0.0049 17.3 1.0 0.028 14.9 0.3 2.5 2 1 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 ETO04663.1 - 0.0052 16.2 0.0 0.0099 15.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RNA_helicase PF00910.17 ETO04663.1 - 0.0079 16.3 3.8 0.14 12.3 1.0 3.3 2 1 0 2 2 2 1 RNA helicase DUF258 PF03193.11 ETO04663.1 - 0.012 14.8 0.2 0.029 13.5 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF258 DUF3074 PF11274.3 ETO04663.1 - 0.033 13.7 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3074) IstB_IS21 PF01695.12 ETO04663.1 - 0.1 11.9 0.1 0.14 11.5 0.0 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein MobB PF03205.9 ETO04663.1 - 0.11 12.2 0.1 0.34 10.6 0.0 1.9 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 ETO04663.1 - 0.17 12.0 0.6 0.99 9.6 0.4 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Enkurin PF13864.1 ETO04663.1 - 0.61 10.3 6.4 0.99 9.6 2.8 2.3 2 1 0 2 2 2 0 Calmodulin-binding AAA_17 PF13207.1 ETO04663.1 - 1.7 9.5 4.3 2.3 9.0 1.5 2.4 2 1 0 2 2 1 0 AAA domain DUF2682 PF10909.3 ETO04664.1 - 2.8 8.2 7.5 21 5.5 1.6 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2682) DUF4256 PF14066.1 ETO04666.1 - 0.067 12.6 0.1 0.099 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4256) LssY_C PF14067.1 ETO04668.1 - 0.0073 15.3 0.0 0.021 13.8 0.0 1.7 1 0 0 1 1 1 1 LssY C-terminus DUF775 PF05603.7 ETO04668.1 - 0.3 10.5 10.2 0.024 14.1 3.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF775) BSP_II PF05432.6 ETO04668.1 - 3.7 6.7 29.1 7.6 5.7 20.1 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) RR_TM4-6 PF06459.7 ETO04668.1 - 10 5.9 21.2 3.6 7.3 4.9 3.2 3 0 0 3 3 3 0 Ryanodine Receptor TM 4-6 SMC_N PF02463.14 ETO04669.1 - 4.2e-22 78.4 2.8 1.1e-21 77.1 0.1 3.1 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 ETO04669.1 - 9.4e-18 65.2 0.1 9.4e-18 65.2 0.1 6.9 4 2 2 6 6 6 1 AAA domain AAA_29 PF13555.1 ETO04669.1 - 4.6e-09 35.6 0.0 9.1e-09 34.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 ETO04669.1 - 0.00021 21.3 0.1 0.00021 21.3 0.0 4.7 5 1 0 5 5 5 1 AAA domain AAA_25 PF13481.1 ETO04669.1 - 0.016 14.6 0.0 0.067 12.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 ETO04669.1 - 0.087 13.1 0.0 0.087 13.1 0.0 5.9 4 2 0 4 4 4 0 ABC transporter AAA_17 PF13207.1 ETO04669.1 - 0.28 11.9 0.0 0.28 11.9 0.0 4.3 6 1 0 6 6 6 0 AAA domain Reo_sigmaC PF04582.7 ETO04669.1 - 1 8.5 8.4 1.3 8.1 0.2 3.7 2 1 1 4 4 4 0 Reovirus sigma C capsid protein Peptidase_C54 PF03416.14 ETO04670.1 - 1.5e-74 250.6 0.2 2e-74 250.2 0.1 1.2 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.8 ETO04670.1 - 0.004 16.2 0.1 0.14 11.2 0.1 2.4 2 0 0 2 2 2 1 Peptidase family C78 MCH PF02289.11 ETO04670.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Cyclohydrolase (MCH) Daxx PF03344.10 ETO04671.1 - 0.0059 15.1 17.4 0.008 14.7 12.1 1.1 1 0 0 1 1 1 1 Daxx Family Spore_coat_CotO PF14153.1 ETO04671.1 - 0.0063 15.9 5.0 0.0064 15.9 3.5 1.3 1 0 0 1 1 1 1 Spore coat protein CotO Nop14 PF04147.7 ETO04671.1 - 0.073 10.9 18.4 0.091 10.6 12.8 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4045 PF13254.1 ETO04671.1 - 0.12 11.6 4.1 0.16 11.2 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Merozoite_SPAM PF07133.6 ETO04671.1 - 0.16 11.8 31.6 0.032 14.1 17.4 2.1 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) Ycf1 PF05758.7 ETO04671.1 - 0.4 8.3 5.0 0.37 8.4 3.5 1.1 1 0 0 1 1 1 0 Ycf1 NOA36 PF06524.7 ETO04671.1 - 0.47 9.6 10.1 0.72 9.0 7.0 1.4 1 0 0 1 1 1 0 NOA36 protein NESP55 PF06390.7 ETO04671.1 - 3.3 7.0 14.5 4.8 6.4 10.0 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) RRN3 PF05327.6 ETO04671.1 - 4.1 5.4 8.4 6.9 4.6 5.8 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2457 PF10446.4 ETO04671.1 - 4.5 5.8 14.0 7.3 5.1 9.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF3381 PF11861.3 ETO04671.1 - 7.2 6.0 17.3 13 5.2 12.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) VID27 PF08553.5 ETO04671.1 - 8 4.5 14.2 11 4.1 9.8 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein Suppressor_APC PF11414.3 ETO04672.1 - 0.0027 17.4 5.6 0.082 12.7 0.2 2.6 1 1 1 2 2 2 2 Adenomatous polyposis coli tumour suppressor protein DUF89 PF01937.14 ETO04672.1 - 0.015 14.1 5.5 0.019 13.7 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF89 Nbl1_Borealin_N PF10444.4 ETO04672.1 - 0.029 13.7 1.3 1.7 8.0 0.5 2.8 2 1 0 2 2 2 0 Nbl1 / Borealin N terminal DUF964 PF06133.6 ETO04672.1 - 0.044 13.7 20.1 0.032 14.2 3.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF964) DASH_Dad1 PF08649.5 ETO04672.1 - 0.098 12.3 0.5 0.38 10.4 0.0 2.2 3 0 0 3 3 2 0 DASH complex subunit Dad1 PMC2NT PF08066.7 ETO04672.1 - 0.11 12.8 2.9 0.28 11.4 0.3 2.1 2 0 0 2 2 2 0 PMC2NT (NUC016) domain AAA_13 PF13166.1 ETO04672.1 - 0.11 10.8 11.6 0.16 10.4 8.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2203 PF09969.4 ETO04672.1 - 0.23 11.6 5.8 1.4 9.1 0.9 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DASH_Dam1 PF08653.5 ETO04672.1 - 0.28 10.9 4.0 11 5.9 0.1 2.8 2 1 0 2 2 2 0 DASH complex subunit Dam1 AAA_27 PF13514.1 ETO04672.1 - 0.51 7.9 10.4 0.68 7.5 7.2 1.1 1 0 0 1 1 1 0 AAA domain Prefoldin_3 PF13758.1 ETO04672.1 - 0.53 10.0 5.7 1.7 8.4 0.3 2.5 2 1 0 2 2 2 0 Prefoldin subunit Prefoldin PF02996.12 ETO04672.1 - 0.55 9.8 15.5 1.9 8.1 0.7 3.2 2 1 1 3 3 3 0 Prefoldin subunit DUF4140 PF13600.1 ETO04672.1 - 0.66 10.4 5.5 11 6.4 0.2 2.7 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) MutS_III PF05192.13 ETO04672.1 - 0.86 9.3 4.2 3.1 7.5 0.1 2.1 1 1 1 2 2 2 0 MutS domain III FliD_N PF02465.13 ETO04672.1 - 1.3 9.4 9.5 0.91 9.9 1.3 2.6 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Phage_GP20 PF06810.6 ETO04672.1 - 1.5 8.2 21.4 0.033 13.6 2.4 2.4 2 1 0 2 2 2 0 Phage minor structural protein GP20 Prefoldin_2 PF01920.15 ETO04672.1 - 1.7 8.4 21.9 0.075 12.8 2.4 3.1 2 1 1 3 3 3 0 Prefoldin subunit DUF2443 PF10398.4 ETO04672.1 - 1.9 8.3 12.3 2 8.2 1.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2443) DUF1664 PF07889.7 ETO04672.1 - 2.7 7.8 9.8 3.7 7.3 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Streptin-Immun PF11083.3 ETO04672.1 - 3 7.8 10.5 1.2 9.1 2.2 2.5 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein Imm42 PF15601.1 ETO04672.1 - 3.2 7.1 6.2 10 5.5 0.5 2.2 2 0 0 2 2 2 0 Immunity protein 42 DUF607 PF04678.8 ETO04672.1 - 5.2 6.9 11.2 13 5.6 1.9 2.5 1 1 1 2 2 2 0 Protein of unknown function, DUF607 DUF3571 PF12095.3 ETO04672.1 - 7.1 6.9 8.6 9 6.6 0.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3571) Sec2p PF06428.6 ETO04672.1 - 8.7 6.2 15.7 4.5 7.1 4.8 2.4 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p Pas_Saposin PF09016.5 ETO04674.1 - 0.04 13.9 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 Pas factor saposin fold DUF2238 PF09997.4 ETO04674.1 - 0.079 12.3 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2238) POP1 PF06978.6 ETO04675.1 - 1.1e-13 51.2 19.5 6.6e-13 48.7 13.5 2.0 1 1 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 DUF1049 PF06305.6 ETO04676.1 - 0.029 13.8 0.1 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Virul_fac_BrkB PF03631.10 ETO04676.1 - 0.091 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Virulence factor BrkB Toxin-deaminase PF14424.1 ETO04677.1 - 0.011 15.7 0.2 0.022 14.7 0.1 1.5 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases TFIIIC_delta PF12657.2 ETO04677.1 - 0.053 13.2 0.1 0.2 11.3 0.1 1.9 1 1 0 1 1 1 0 Transcription factor IIIC subunit delta N-term Peptidase_S49_N PF08496.5 ETO04678.1 - 4.1 7.1 5.8 6.4 6.5 0.7 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal RAMP4 PF06624.7 ETO04679.1 - 0.34 10.4 2.2 1.1 8.8 1.5 1.8 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 DUF1510 PF07423.6 ETO04680.1 - 0.0068 15.7 14.0 0.0068 15.7 9.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) Nop14 PF04147.7 ETO04680.1 - 0.51 8.2 24.0 0.56 8.0 16.6 1.1 1 0 0 1 1 1 0 Nop14-like family Ycf1 PF05758.7 ETO04680.1 - 1.7 6.2 9.7 2 6.0 6.7 1.2 1 0 0 1 1 1 0 Ycf1 Daxx PF03344.10 ETO04680.1 - 1.7 7.0 29.0 2.3 6.6 20.1 1.0 1 0 0 1 1 1 0 Daxx Family DUF1980 PF09323.5 ETO04680.1 - 2.7 7.6 10.8 0.073 12.8 0.9 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF1980) Sigma_reg_C PF13791.1 ETO04680.1 - 3.6 7.6 13.2 1.1 9.2 6.9 1.8 1 1 1 2 2 2 0 Sigma factor regulator C-terminal CDC45 PF02724.9 ETO04680.1 - 4 5.3 18.8 5.1 5.0 13.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Dicty_REP PF05086.7 ETO04680.1 - 8.8 3.9 15.7 9.6 3.8 10.9 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SAM_2 PF07647.12 ETO04681.1 - 2.6e-05 23.9 0.1 0.00041 20.1 0.0 2.2 1 1 1 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO04681.1 - 0.0015 18.6 0.0 0.003 17.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 ETO04681.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain DUF382 PF04037.8 ETO04682.1 - 0.0062 16.3 0.4 1.8 8.3 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF382) Baculo_FP PF03258.9 ETO04683.1 - 0.043 12.9 0.0 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 Baculovirus FP protein DUF1180 PF06679.7 ETO04683.1 - 0.14 11.9 0.2 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Coiled PF05710.7 ETO04683.1 - 8.8 6.8 8.5 18 5.8 5.9 1.5 1 0 0 1 1 1 0 Coiled coil Laminin_G_3 PF13385.1 ETO04684.1 - 3.2e-19 69.7 2.3 4e-19 69.3 0.9 1.7 1 1 1 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Pentaxin PF00354.12 ETO04684.1 - 0.051 13.0 0.1 0.33 10.3 0.0 2.0 1 1 0 1 1 1 0 Pentaxin family DUF4467 PF14729.1 ETO04685.1 - 2.5 8.4 8.7 0.91 9.8 4.0 1.7 1 1 0 1 1 1 0 Domain of unknown function with cystatin-like fold (DUF4467) YqzE PF14038.1 ETO04686.1 - 0.068 12.9 0.1 0.096 12.4 0.1 1.2 1 0 0 1 1 1 0 YqzE-like protein Cation_efflux PF01545.16 ETO04688.1 - 5.7 5.9 11.6 10 5.1 8.1 1.4 1 0 0 1 1 1 0 Cation efflux family HgmA PF04209.8 ETO04691.1 - 0.013 13.9 0.0 0.015 13.7 0.0 1.0 1 0 0 1 1 1 0 homogentisate 1,2-dioxygenase Sec62 PF03839.11 ETO04692.1 - 0.038 13.3 0.4 0.038 13.3 0.3 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 DUF1430 PF07242.6 ETO04692.1 - 2.6 8.1 8.2 0.7 9.9 0.6 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1430) DEAD PF00270.24 ETO04693.1 - 3.8e-08 33.0 0.2 4.7e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Pico_P1A PF02226.11 ETO04693.1 - 0.11 12.1 0.5 0.24 11.1 0.3 1.6 1 0 0 1 1 1 0 Picornavirus coat protein (VP4) MIT PF04212.13 ETO04695.1 - 1.2e-09 37.8 7.7 6.4e-09 35.5 5.3 1.9 1 1 0 1 1 1 1 MIT (microtubule interacting and transport) domain CDC37_N PF03234.9 ETO04695.1 - 0.05 13.9 6.5 0.06 13.6 4.5 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding TPR_1 PF00515.23 ETO04695.1 - 0.068 12.8 0.6 0.24 11.0 0.4 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat BLVR PF06375.6 ETO04695.1 - 0.18 11.6 6.0 0.22 11.3 4.1 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) FliS PF02561.9 ETO04695.1 - 0.27 11.0 6.0 0.14 11.9 1.7 1.9 1 1 1 2 2 2 0 Flagellar protein FliS bZIP_C PF12498.3 ETO04695.1 - 0.36 12.0 2.1 0.45 11.7 1.5 1.4 1 1 0 1 1 1 0 Basic leucine-zipper C terminal VSG_B PF13206.1 ETO04695.1 - 0.62 9.1 8.3 0.71 8.9 5.7 1.0 1 0 0 1 1 1 0 Trypanosomal VSG domain DUF3897 PF13036.1 ETO04695.1 - 0.66 9.5 8.4 0.15 11.6 2.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3897) DUF2891 PF11199.3 ETO04696.1 - 0.0079 14.8 0.1 0.011 14.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2891) SAPS PF04499.10 ETO04696.1 - 0.0091 14.6 0.1 0.0097 14.5 0.0 1.2 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Med19 PF10278.4 ETO04696.1 - 1.5 8.4 13.8 1.3 8.6 7.1 2.1 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Cofilin_ADF PF00241.15 ETO04697.1 - 1.1e-07 31.7 0.9 2.1e-07 30.8 0.6 1.6 1 1 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF2750 PF11042.3 ETO04697.1 - 0.012 15.5 0.0 0.034 14.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2750) RICTOR_N PF14664.1 ETO04698.1 - 0.054 12.0 0.1 0.065 11.8 0.1 1.2 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term eRF1_1 PF03463.10 ETO04699.1 - 5.5e-07 29.2 0.5 8.4e-07 28.6 0.3 1.4 1 0 0 1 1 1 1 eRF1 domain 1 DUF4290 PF14123.1 ETO04699.1 - 0.0073 15.5 0.2 0.0073 15.5 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4290) TRM13 PF05206.9 ETO04699.1 - 0.05 12.8 5.4 0.036 13.2 0.9 2.1 1 1 0 2 2 2 0 Methyltransferase TRM13 WD40 PF00400.27 ETO04700.1 - 1.8e-06 27.5 0.5 2.8e-06 26.9 0.3 1.3 1 0 0 1 1 1 1 WD domain, G-beta repeat DUF4164 PF13747.1 ETO04700.1 - 0.0018 18.3 1.8 0.0028 17.7 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4164) Cep57_CLD_2 PF14197.1 ETO04700.1 - 0.016 15.1 6.8 0.024 14.5 4.7 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Rootletin PF15035.1 ETO04700.1 - 0.18 11.7 7.3 0.23 11.4 5.1 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion HAP1_N PF04849.8 ETO04700.1 - 0.18 10.7 11.2 0.4 9.5 7.6 1.6 1 1 0 1 1 1 0 HAP1 N-terminal conserved region YusW PF14039.1 ETO04700.1 - 0.24 11.7 4.6 0.34 11.2 3.2 1.5 1 1 0 1 1 1 0 YusW-like protein ERM PF00769.14 ETO04700.1 - 0.63 9.5 11.4 0.76 9.2 7.9 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family IncA PF04156.9 ETO04700.1 - 0.95 9.0 7.9 1.1 8.8 5.5 1.1 1 0 0 1 1 1 0 IncA protein WHEP-TRS PF00458.15 ETO04700.1 - 1.4 8.6 5.1 6.8 6.4 0.1 2.4 2 1 0 2 2 2 0 WHEP-TRS domain TPX2 PF06886.6 ETO04700.1 - 2.3 8.3 8.0 7.5 6.6 5.5 1.9 1 1 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) DUF2681 PF10883.3 ETO04700.1 - 3.1 8.0 10.5 37 4.6 7.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) DUF342 PF03961.8 ETO04700.1 - 3.4 5.9 8.6 3.6 5.8 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Ly49 PF08391.5 ETO04700.1 - 9.7 6.3 12.7 16 5.6 8.8 1.5 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region WD40 PF00400.27 ETO04701.1 - 9.6e-05 22.1 1.8 0.00047 19.9 0.1 2.7 3 0 0 3 3 3 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO04701.1 - 0.0093 14.1 0.0 0.011 13.8 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 WD40 PF00400.27 ETO04704.1 - 1.2e-60 199.3 25.4 3.9e-10 39.2 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO04704.1 - 1.7e-10 39.6 9.4 0.012 13.7 0.2 5.8 2 1 2 5 5 5 5 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO04704.1 - 0.00056 20.2 1.6 0.00056 20.2 1.1 3.0 2 1 0 2 2 2 1 TRAF-type zinc finger FlaC_arch PF05377.6 ETO04704.1 - 1.3 9.0 9.4 1.8 8.5 5.0 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) zf-TRAF PF02176.13 ETO04705.1 - 6.5e-07 29.6 1.9 6.5e-07 29.6 1.3 2.5 2 0 0 2 2 2 1 TRAF-type zinc finger zf-RING_2 PF13639.1 ETO04705.1 - 0.075 12.8 0.6 0.075 12.8 0.4 2.5 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.1 ETO04705.1 - 0.09 12.8 0.5 0.09 12.8 0.3 2.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) LELP1 PF15042.1 ETO04705.1 - 6.4 7.0 8.1 11 6.2 0.6 2.2 1 1 1 2 2 2 0 Late cornified envelope-like proline-rich protein 1 Sigma70_ner PF04546.8 ETO04707.1 - 3.7 7.1 9.1 3.5 7.1 6.3 1.0 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.4 ETO04707.1 - 3.8 6.1 22.8 4.2 6.0 15.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PBP1_TM PF14812.1 ETO04707.1 - 4.9 7.5 12.7 5.2 7.4 8.8 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Kelch_3 PF13415.1 ETO04709.1 - 5.4e-05 23.2 0.6 0.00029 20.8 0.0 2.1 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO04709.1 - 0.00012 21.5 0.1 0.00025 20.5 0.1 1.5 1 0 0 1 1 1 1 Kelch motif Kelch_4 PF13418.1 ETO04709.1 - 0.0017 18.0 0.0 0.0051 16.5 0.0 1.7 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO04709.1 - 0.022 14.9 0.1 0.16 12.1 0.1 2.2 2 0 0 2 2 2 0 Kelch motif Kelch_5 PF13854.1 ETO04709.1 - 0.026 14.4 0.4 0.075 13.0 0.3 1.8 2 0 0 2 2 2 0 Kelch motif EpoR_lig-bind PF09067.5 ETO04709.1 - 0.06 13.3 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Erythropoietin receptor, ligand binding MtrC PF04211.8 ETO04710.1 - 0.033 13.2 5.6 0.05 12.6 3.9 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit C YkuI_C PF10388.4 ETO04710.1 - 0.52 9.9 4.5 0.26 10.9 1.6 1.5 2 0 0 2 2 2 0 EAL-domain associated signalling protein domain Gly-zipper_Omp PF13488.1 ETO04710.1 - 0.68 9.6 13.5 1.5 8.4 9.3 1.5 1 0 0 1 1 1 0 Glycine zipper TraT PF05818.7 ETO04710.1 - 2.1 7.7 4.7 4.6 6.5 3.3 1.5 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Rick_17kDa_Anti PF05433.10 ETO04710.1 - 4.5 7.0 17.7 16 5.2 12.3 1.9 1 1 0 1 1 1 0 Glycine zipper 2TM domain RP-C_C PF11800.3 ETO04711.1 - 0.16 11.6 9.3 0.44 10.2 1.4 2.4 2 0 0 2 2 2 0 Replication protein C C-terminal region Raftlin PF15250.1 ETO04711.1 - 0.33 9.4 10.3 0.41 9.1 1.1 2.2 2 0 0 2 2 2 0 Raftlin Zip PF02535.17 ETO04711.1 - 0.34 9.8 6.8 0.92 8.4 0.7 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter TraU PF06834.6 ETO04711.1 - 0.98 8.4 5.2 0.11 11.6 0.1 1.8 2 0 0 2 2 2 0 TraU protein Pox_Ag35 PF03286.9 ETO04711.1 - 1.7 8.1 14.5 3.6 7.0 0.8 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Bap31 PF05529.7 ETO04711.1 - 2 7.8 6.6 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Peptidase_S49_N PF08496.5 ETO04711.1 - 2.3 7.9 8.9 3.6 7.3 3.3 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal FAM176 PF14851.1 ETO04711.1 - 2.9 7.5 10.9 12 5.6 0.1 2.3 2 0 0 2 2 2 0 FAM176 family SID-1_RNA_chan PF13965.1 ETO04711.1 - 5.8 4.9 10.1 0.67 8.0 1.2 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Yippee-Mis18 PF03226.9 ETO04712.1 - 7.6 6.6 8.4 22 5.1 5.0 2.4 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly GPCR_chapero_1 PF11904.3 ETO04717.1 - 0.03 13.4 0.1 0.048 12.8 0.1 1.3 1 0 0 1 1 1 0 GPCR-chaperone HATPase_c_3 PF13589.1 ETO04719.1 - 2.9e-06 26.9 0.8 0.0002 21.0 0.0 2.4 2 1 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 ETO04719.1 - 6.6e-06 25.8 0.3 3.5e-05 23.4 0.2 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4179 PF13786.1 ETO04719.1 - 0.17 12.1 2.6 4.5 7.5 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) HSP90 PF00183.13 ETO04720.1 - 5.1e-53 180.2 16.9 5.2e-53 180.2 10.1 1.8 1 1 1 2 2 2 2 Hsp90 protein PhoD PF09423.5 ETO04721.1 - 1.6e-05 23.6 0.2 1.7e-05 23.5 0.1 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase EF-hand_7 PF13499.1 ETO04722.1 - 0.00022 21.3 0.0 0.0018 18.3 0.0 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO04722.1 - 0.00032 19.7 0.0 0.049 12.9 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 ETO04722.1 - 0.01 15.6 0.4 5 7.2 0.0 2.7 2 1 1 3 3 3 0 EF-hand domain EF-hand_8 PF13833.1 ETO04722.1 - 0.016 14.8 0.0 0.053 13.1 0.0 1.9 1 1 0 1 1 1 0 EF-hand domain pair Viral_env_E26 PF11050.3 ETO04722.1 - 0.024 13.8 1.2 0.032 13.4 0.7 1.3 1 1 0 1 1 1 0 Virus envelope protein E26 DUF1304 PF06993.7 ETO04723.1 - 0.13 11.9 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) Ycf1 PF05758.7 ETO04724.1 - 1.1 6.8 26.9 1.3 6.6 18.7 1.1 1 0 0 1 1 1 0 Ycf1 GBP_C PF02841.9 ETO04724.1 - 3 6.9 40.4 3.3 6.8 28.0 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain HAUS6_N PF14661.1 ETO04724.1 - 4.6 6.5 31.7 5.6 6.2 21.9 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Allexi_40kDa PF05549.6 ETO04724.1 - 7.3 5.7 13.0 9.1 5.4 9.0 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein SDH_beta PF03315.10 ETO04724.1 - 8.3 6.4 7.0 16 5.5 4.9 1.6 1 1 0 1 1 1 0 Serine dehydratase beta chain CAF-1_p150 PF11600.3 ETO04724.1 - 8.6 5.6 53.0 9.7 5.4 36.7 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Caldesmon PF02029.10 ETO04724.1 - 9.5 4.5 39.0 12 4.2 27.0 1.1 1 0 0 1 1 1 0 Caldesmon Band_7 PF01145.20 ETO04725.1 - 1.8e-17 63.8 3.4 1.8e-17 63.8 2.3 1.5 2 0 0 2 2 2 1 SPFH domain / Band 7 family Adeno_E4 PF05385.6 ETO04725.1 - 0.11 12.4 0.2 0.44 10.5 0.0 2.0 2 0 0 2 2 2 0 Mastadenovirus early E4 13 kDa protein Glyco_tran_WbsX PF14307.1 ETO04726.1 - 0.0067 15.6 1.0 0.012 14.8 0.2 1.6 2 0 0 2 2 2 1 Glycosyltransferase WbsX Asp PF00026.18 ETO04726.1 - 0.14 11.4 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic aspartyl protease IBR PF01485.16 ETO04727.1 - 1.6e-07 31.1 39.2 0.00012 21.9 13.6 3.8 3 1 0 3 3 3 2 IBR domain DUF221 PF02714.10 ETO04728.1 - 0.18 10.6 4.4 0.22 10.3 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF221 Pkinase PF00069.20 ETO04729.1 - 0.013 14.6 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain DUF2222 PF09984.4 ETO04730.1 - 0.18 11.2 5.5 0.51 9.7 3.8 1.7 1 1 0 1 1 1 0 Uncharacterized signal transduction histidine kinase domain (DUF2222) AAL_decarboxy PF03306.8 ETO04730.1 - 0.97 8.4 4.5 1.2 8.1 3.1 1.2 1 0 0 1 1 1 0 Alpha-acetolactate decarboxylase HA2 PF04408.18 ETO04730.1 - 2.8 8.0 6.4 10 6.2 4.4 1.9 1 1 0 1 1 1 0 Helicase associated domain (HA2) Pkinase PF00069.20 ETO04731.1 - 1.4e-12 47.3 1.5 3.3e-12 46.1 0.0 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO04731.1 - 0.0051 15.9 0.3 0.01 14.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_C PF00433.19 ETO04731.1 - 0.0063 17.0 0.0 0.0063 17.0 0.0 2.4 2 1 0 2 2 2 1 Protein kinase C terminal domain DUF4407 PF14362.1 ETO04731.1 - 0.94 8.3 4.1 1.3 7.8 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF572 PF04502.8 ETO04731.1 - 1.3 8.1 15.5 1.6 7.8 10.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Pex14_N PF04695.8 ETO04731.1 - 6.5 6.7 14.0 0.52 10.3 5.9 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region GPCR_chapero_1 PF11904.3 ETO04732.1 - 0.0083 15.3 0.1 0.012 14.8 0.0 1.1 1 0 0 1 1 1 1 GPCR-chaperone CDC45 PF02724.9 ETO04732.1 - 0.033 12.2 1.6 0.031 12.3 1.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Rad50_zn_hook PF04423.9 ETO04732.1 - 0.13 11.7 0.1 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif DUF1840 PF08895.6 ETO04732.1 - 0.31 11.0 2.0 1.8 8.6 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) FLO_LFY PF01698.11 ETO04732.1 - 0.95 8.2 6.0 1.2 7.8 4.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein zf-RING_2 PF13639.1 ETO04733.1 - 0.00019 21.2 1.9 0.00036 20.2 0.3 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 ETO04733.1 - 0.035 13.8 0.8 0.074 12.7 0.6 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 ETO04733.1 - 0.14 12.1 0.9 0.38 10.8 0.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETO04733.1 - 0.39 10.8 1.7 2 8.5 1.2 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 ETO04733.1 - 0.87 9.2 3.3 0.42 10.3 0.5 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Kelch_4 PF13418.1 ETO04734.1 - 1.8e-19 69.2 12.5 1.7e-09 37.2 0.1 5.7 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO04734.1 - 3.6e-15 55.5 3.8 2.8e-05 23.9 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 ETO04734.1 - 1e-13 50.8 8.3 5.1e-07 29.6 0.0 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 ETO04734.1 - 3.2e-12 46.2 21.0 3.4e-06 27.0 0.1 6.7 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO04734.1 - 2.1e-10 39.9 15.0 1.2e-08 34.3 0.0 5.1 5 1 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO04734.1 - 5.1e-08 32.3 8.4 1.3e-07 31.0 0.0 4.6 5 1 0 5 5 5 1 Kelch motif WD40 PF00400.27 ETO04735.1 - 1.5e-26 91.2 1.8 2e-06 27.4 0.0 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat Nbas_N PF15492.1 ETO04735.1 - 1.4e-05 24.3 1.6 0.52 9.3 0.0 4.0 1 1 3 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 ETO04735.1 - 7.6e-05 22.2 0.1 0.52 10.0 0.0 4.6 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Utp8 PF10395.4 ETO04735.1 - 0.00063 18.1 2.6 0.0015 16.9 0.2 2.4 2 1 1 3 3 3 1 Utp8 family SGL PF08450.7 ETO04735.1 - 0.00065 19.1 0.3 1.3 8.3 0.1 3.2 2 1 1 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region Nucleoporin_N PF08801.6 ETO04735.1 - 0.0014 17.4 8.2 0.0067 15.2 4.4 2.5 1 1 1 2 2 2 1 Nup133 N terminal like DPPIV_N PF00930.16 ETO04735.1 - 0.0022 16.6 0.0 0.25 9.8 0.0 2.7 1 1 1 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region TonB_2 PF13103.1 ETO04735.1 - 0.0064 16.5 0.1 0.3 11.1 0.0 2.9 2 1 1 3 3 3 1 TonB C terminal PQQ_2 PF13360.1 ETO04735.1 - 0.0065 15.9 0.0 0.045 13.2 0.0 2.1 1 1 1 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO04735.1 - 0.01 14.1 0.1 3.7 5.7 0.0 2.8 2 1 1 3 3 3 0 Cytochrome D1 heme domain Nup160 PF11715.3 ETO04735.1 - 0.01 13.9 0.0 2.5 6.1 0.0 2.6 1 1 2 3 3 3 0 Nucleoporin Nup120/160 TFIIH_BTF_p62_N PF08567.6 ETO04735.1 - 0.036 13.7 0.1 9.7 5.9 0.0 3.3 3 0 0 3 3 3 0 TFIIH p62 subunit, N-terminal domain Proteasome_A_N PF10584.4 ETO04735.1 - 0.05 12.9 2.7 6 6.2 0.0 3.0 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Ricin_B_lectin PF00652.17 ETO04735.1 - 0.13 12.2 2.5 13 5.8 0.1 2.9 1 1 2 3 3 3 0 Ricin-type beta-trefoil lectin domain Kelch_6 PF13964.1 ETO04736.1 - 3.8e-08 33.1 11.0 0.005 16.9 0.3 4.4 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO04736.1 - 3e-07 29.8 8.4 0.01 15.3 0.3 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO04736.1 - 1.4e-05 25.1 1.6 0.1 12.7 0.0 4.3 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO04736.1 - 2.2e-05 24.1 4.9 0.31 10.8 0.1 4.7 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO04736.1 - 0.0023 17.8 4.9 0.58 10.1 0.6 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO04736.1 - 0.055 13.2 2.3 8.1 6.3 0.0 4.6 5 0 0 5 5 5 0 Kelch motif PT-HINT PF07591.6 ETO04737.1 - 1.3e-08 34.8 0.7 1.1e-07 31.7 0.5 2.4 1 1 0 1 1 1 1 Pretoxin HINT domain AXH PF08517.7 ETO04737.1 - 2.9e-08 33.8 0.1 7.6e-08 32.5 0.1 1.7 1 0 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) Hint PF01079.15 ETO04737.1 - 0.00041 19.6 0.0 0.0065 15.6 0.0 2.2 1 1 0 1 1 1 1 Hint module Hint_2 PF13403.1 ETO04737.1 - 0.0014 18.5 0.0 0.23 11.3 0.1 2.4 2 0 0 2 2 2 1 Hint domain Hom_end_hint PF05203.11 ETO04737.1 - 0.0048 16.6 3.1 0.018 14.7 0.1 2.7 3 0 0 3 3 3 1 Hom_end-associated Hint Toxin-deaminase PF14424.1 ETO04737.1 - 0.054 13.4 0.9 0.098 12.6 0.6 1.4 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases Myb_CC_LHEQLE PF14379.1 ETO04737.1 - 0.054 13.0 2.1 0.12 12.0 1.4 1.5 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif Folate_carrier PF01770.13 ETO04738.1 - 0.056 11.9 0.1 0.096 11.1 0.0 1.4 1 0 0 1 1 1 0 Reduced folate carrier POX PF07526.6 ETO04738.1 - 3.5 7.8 14.8 0.11 12.6 0.2 3.1 2 1 2 4 4 4 0 Associated with HOX zf-CCHC PF00098.18 ETO04740.1 - 0.00024 20.8 1.9 0.00053 19.7 1.3 1.6 1 0 0 1 1 1 1 Zinc knuckle V-ATPase_H_C PF11698.3 ETO04740.1 - 0.1 12.4 2.0 0.35 10.7 0.2 2.0 1 1 1 2 2 2 0 V-ATPase subunit H Pox_polyA_pol_N PF12630.2 ETO04740.1 - 1.5 8.9 4.9 0.47 10.5 1.1 1.9 2 1 0 2 2 2 0 Poxvirus poly(A) polymerase N-terminal domain UCH PF00443.24 ETO04741.1 - 5.7e-33 114.1 6.5 6.3e-20 71.4 0.2 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO04741.1 - 2.6e-11 43.5 13.0 1.8e-10 40.7 9.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase BNIP3 PF06553.7 ETO04742.1 - 0.027 13.8 0.4 0.031 13.6 0.3 1.1 1 0 0 1 1 1 0 BNIP3 Jnk-SapK_ap_N PF09744.4 ETO04743.1 - 0.063 13.2 2.5 0.067 13.1 1.7 1.0 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 ETRAMP PF09716.5 ETO04743.1 - 0.68 9.9 3.9 0.87 9.5 2.7 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF912 PF06024.7 ETO04743.1 - 2.3 8.3 6.6 2.5 8.1 4.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Dak1_2 PF13684.1 ETO04744.1 - 0.022 13.6 0.3 0.032 13.1 0.2 1.1 1 0 0 1 1 1 0 Dihydroxyacetone kinase family PrkA PF06798.7 ETO04744.1 - 0.06 12.6 1.8 0.082 12.1 1.3 1.2 1 0 0 1 1 1 0 PrkA serine protein kinase C-terminal domain SPOUT_MTase PF02590.12 ETO04744.1 - 0.083 12.6 1.2 0.11 12.2 0.8 1.3 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase RNA_GG_bind PF10258.4 ETO04744.1 - 0.61 9.8 3.0 5.6 6.7 1.2 2.5 2 1 0 2 2 2 0 PHAX RNA-binding domain CAP_GLY PF01302.20 ETO04745.1 - 4.9e-24 83.8 1.0 9.7e-15 54.0 0.2 2.5 2 0 0 2 2 2 2 CAP-Gly domain PX PF00787.19 ETO04747.1 - 2.8e-16 59.3 0.8 2.8e-16 59.3 0.6 2.5 3 0 0 3 3 3 1 PX domain TMV_coat PF00721.16 ETO04747.1 - 0.0069 16.3 2.2 10 6.0 0.0 3.3 3 0 0 3 3 3 2 Virus coat protein (TMV like) CAP_GLY PF01302.20 ETO04748.1 - 1.7e-35 120.5 4.0 2.8e-18 65.3 0.3 2.1 2 0 0 2 2 2 2 CAP-Gly domain MH2 PF03166.9 ETO04748.1 - 0.0056 16.5 0.1 1.3 8.8 0.0 2.2 2 0 0 2 2 2 2 MH2 domain IL33 PF15095.1 ETO04748.1 - 0.029 13.8 0.7 1.6 8.0 0.1 2.1 2 0 0 2 2 2 0 Interleukin 33 Ribosomal_L12 PF00542.14 ETO04750.1 - 4e-22 77.9 7.8 4e-22 77.9 5.4 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Cdd1 PF11731.3 ETO04750.1 - 0.06 13.2 0.1 9 6.3 0.0 2.5 2 1 0 2 2 2 0 Pathogenicity locus Cauli_AT PF03233.8 ETO04750.1 - 0.14 11.8 4.0 0.16 11.6 0.2 2.0 2 0 0 2 2 2 0 Aphid transmission protein Asn_synthase PF00733.16 ETO04751.1 - 2.5e-16 59.9 0.0 3.3e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase Cas_Csx9 PF09658.5 ETO04752.1 - 0.075 11.8 0.1 0.82 8.4 0.0 2.0 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Csx9) SCP2_2 PF13530.1 ETO04753.1 - 0.077 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Sterol carrier protein domain LRR_4 PF12799.2 ETO04755.1 - 2.9e-14 52.2 20.6 1.4e-06 27.7 3.3 5.4 2 1 5 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO04755.1 - 6.8e-10 38.5 15.9 4.3e-05 23.1 2.9 3.7 1 1 3 4 4 4 4 Leucine rich repeat LRR_9 PF14580.1 ETO04755.1 - 0.00012 21.7 6.9 0.00014 21.4 2.6 2.3 2 1 0 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.28 ETO04755.1 - 0.00033 20.2 22.5 0.59 10.3 0.6 7.1 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.1 ETO04755.1 - 0.00066 19.4 20.6 5.2 7.4 0.6 6.9 6 0 0 6 6 6 2 Leucine Rich repeat Alpha_kinase PF02816.13 ETO04755.1 - 0.0056 16.3 0.2 0.019 14.6 0.1 1.9 1 0 0 1 1 1 1 Alpha-kinase family LRR_7 PF13504.1 ETO04755.1 - 0.14 12.4 12.4 85 4.0 0.0 6.8 6 0 0 6 6 6 0 Leucine rich repeat CDC45 PF02724.9 ETO04755.1 - 1.1 7.2 6.6 1.5 6.7 4.6 1.2 1 0 0 1 1 1 0 CDC45-like protein TRAPP PF04051.11 ETO04757.1 - 0.031 13.8 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 Transport protein particle (TRAPP) component ANAPC15 PF15243.1 ETO04758.1 - 0.0049 16.9 4.8 0.009 16.0 3.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 15 Innate_immun PF12782.2 ETO04758.1 - 0.18 10.9 7.5 0.22 10.6 5.2 1.1 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family WD40 PF00400.27 ETO04759.1 - 1.3e-30 104.1 11.1 2.7e-11 42.8 1.9 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO04759.1 - 1.3e-07 30.1 0.4 0.00012 20.3 1.0 2.8 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO04759.1 - 0.098 12.8 1.7 14 6.0 0.1 2.6 2 0 0 2 2 2 0 Kelch motif TIP41 PF04176.8 ETO04761.1 - 0.013 14.7 0.1 0.18 11.0 0.0 2.0 2 0 0 2 2 2 0 TIP41-like family NPR2 PF06218.6 ETO04762.1 - 1.6 7.3 3.6 2 6.9 2.5 1.1 1 0 0 1 1 1 0 Nitrogen permease regulator 2 WD40 PF00400.27 ETO04763.1 - 0.022 14.6 0.4 0.33 10.9 0.1 2.2 2 0 0 2 2 2 0 WD domain, G-beta repeat Peptidase_S13 PF02113.10 ETO04763.1 - 0.08 11.4 0.0 0.087 11.3 0.0 1.0 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family Thg1C PF14413.1 ETO04763.1 - 0.22 11.2 2.1 0.41 10.3 1.4 1.6 1 1 0 1 1 1 0 Thg1 C terminal domain Y_phosphatase2 PF03162.8 ETO04764.1 - 0.036 13.4 0.9 0.058 12.7 0.6 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family IKI3 PF04762.7 ETO04766.1 - 0.034 11.9 0.0 0.034 11.9 0.0 1.2 1 0 0 1 1 1 0 IKI3 family WD40 PF00400.27 ETO04766.1 - 0.44 10.5 2.4 4.3 7.3 0.0 3.5 4 0 0 4 4 4 0 WD domain, G-beta repeat DRY_EERY PF09750.4 ETO04768.1 - 0.011 15.8 0.8 0.016 15.2 0.1 1.6 1 1 1 2 2 2 0 Alternative splicing regulator Cwf_Cwc_15 PF04889.7 ETO04769.1 - 0.083 12.5 17.2 0.11 12.1 12.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CT47 PF15623.1 ETO04769.1 - 0.38 10.4 16.2 0.47 10.1 11.2 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 mRNA_cap_C PF03919.10 ETO04770.1 - 1.4e-08 34.9 0.1 4.3e-08 33.4 0.0 1.9 2 1 0 2 2 2 1 mRNA capping enzyme, C-terminal domain MtmB PF05369.7 ETO04770.1 - 0.19 9.8 0.1 0.26 9.3 0.1 1.1 1 0 0 1 1 1 0 Monomethylamine methyltransferase MtmB Peptidase_M54 PF07998.6 ETO04771.1 - 7.8e-10 38.8 1.9 1e-09 38.4 1.3 1.1 1 0 0 1 1 1 1 Peptidase family M54 Reprolysin_2 PF13574.1 ETO04771.1 - 0.0088 16.1 0.2 0.01 15.8 0.2 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 ETO04771.1 - 0.031 14.2 0.8 0.047 13.6 0.3 1.5 1 1 1 2 2 2 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 ETO04771.1 - 0.035 13.6 0.1 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.3 ETO04771.1 - 0.057 11.8 2.0 0.077 11.4 1.2 1.3 1 1 0 1 1 1 0 Putative peptidase family Peptidase_M10 PF00413.19 ETO04771.1 - 0.065 12.9 0.2 0.097 12.3 0.2 1.3 1 0 0 1 1 1 0 Matrixin zf-MIZ PF02891.15 ETO04771.1 - 0.13 11.7 0.8 0.24 10.9 0.5 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Reprolysin_3 PF13582.1 ETO04771.1 - 1.3 9.5 3.1 1.2 9.6 1.3 1.6 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like PP2C PF00481.16 ETO04772.1 - 5.9e-33 114.3 0.2 7.1e-33 114.0 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 ETO04772.1 - 7.7e-05 22.4 0.0 0.00011 21.9 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 ETO04772.1 - 0.00016 21.1 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Ribosomal_L14 PF00238.14 ETO04772.1 - 0.1 12.3 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L14p/L23e XRN_N PF03159.13 ETO04773.1 - 0.0041 16.5 1.5 0.0041 16.5 1.1 2.2 2 1 1 3 3 3 1 XRN 5'-3' exonuclease N-terminus Kelch_1 PF01344.20 ETO04775.1 - 5.2e-08 32.3 4.5 0.00034 20.1 0.5 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO04775.1 - 1.8e-06 27.6 0.1 0.00058 19.5 0.0 3.5 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO04775.1 - 3.4e-05 23.8 3.3 0.92 9.7 0.0 4.7 4 1 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO04775.1 - 0.11 12.2 6.0 36 4.3 1.3 4.7 4 1 0 4 4 4 0 Kelch motif Kelch_5 PF13854.1 ETO04775.1 - 0.12 12.3 3.0 0.43 10.5 0.0 3.2 5 0 0 5 5 5 0 Kelch motif bZIP_C PF12498.3 ETO04776.1 - 4.2 8.6 10.4 0.74 11.0 4.5 1.8 2 0 0 2 2 2 0 Basic leucine-zipper C terminal POX PF07526.6 ETO04776.1 - 6.2 7.0 6.4 2.4 8.3 2.5 1.7 2 0 0 2 2 2 0 Associated with HOX Secretin_N_2 PF07655.8 ETO04776.1 - 8.4 6.8 11.5 16 5.9 8.0 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain FANCI_S3 PF14677.1 ETO04777.1 - 0.029 13.7 0.0 0.054 12.8 0.0 1.5 1 0 0 1 1 1 0 FANCI solenoid 3 Ground-like PF04155.13 ETO04777.1 - 0.03 14.6 1.2 0.53 10.6 0.0 2.3 2 0 0 2 2 2 0 Ground-like domain PRCC PF10253.4 ETO04777.1 - 0.19 12.3 0.5 0.24 12.0 0.3 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting HAP1_N PF04849.8 ETO04778.1 - 0.0017 17.3 25.5 0.0021 17.0 8.2 2.1 1 1 1 2 2 2 1 HAP1 N-terminal conserved region Exonuc_VII_L PF02601.10 ETO04778.1 - 0.0041 16.3 13.5 0.0051 16.0 9.4 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit Tropomyosin PF00261.15 ETO04778.1 - 0.0051 15.9 23.2 0.0078 15.3 16.1 1.2 1 0 0 1 1 1 1 Tropomyosin CALCOCO1 PF07888.6 ETO04778.1 - 0.064 11.5 23.9 0.08 11.2 16.6 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Takusan PF04822.8 ETO04778.1 - 0.069 12.9 31.3 0.78 9.5 5.1 3.4 1 1 2 3 3 3 0 Takusan DASH_Dad4 PF08650.5 ETO04778.1 - 0.13 12.1 2.6 0.19 11.6 0.5 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad4 Seryl_tRNA_N PF02403.17 ETO04778.1 - 0.47 10.5 24.1 1.8 8.5 10.6 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Laminin_II PF06009.7 ETO04778.1 - 0.5 10.1 12.3 0.17 11.6 5.0 2.1 1 1 1 2 2 2 0 Laminin Domain II Vps5 PF09325.5 ETO04778.1 - 0.59 9.3 19.3 0.24 10.6 2.8 2.4 1 1 1 2 2 2 0 Vps5 C terminal like GAS PF13851.1 ETO04778.1 - 0.93 8.6 28.3 0.67 9.1 9.8 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF342 PF03961.8 ETO04778.1 - 1.4 7.2 23.4 0.87 7.9 8.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) MCPsignal PF00015.16 ETO04778.1 - 1.4 8.3 10.6 1.8 8.0 0.8 2.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain APG6 PF04111.7 ETO04778.1 - 1.6 7.7 27.7 0.74 8.8 9.8 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Prefoldin_2 PF01920.15 ETO04778.1 - 2 8.2 28.2 2.8 7.7 2.2 3.4 2 1 0 2 2 2 0 Prefoldin subunit Nsp1_C PF05064.8 ETO04778.1 - 2.6 7.6 17.0 0.84 9.2 1.7 2.7 1 1 1 2 2 2 0 Nsp1-like C-terminal region TPR_MLP1_2 PF07926.7 ETO04778.1 - 2.8 7.7 24.6 42 3.8 16.3 2.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Nup54 PF13874.1 ETO04778.1 - 3 7.4 22.6 3.4 7.3 3.8 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF1664 PF07889.7 ETO04778.1 - 3.8 7.3 13.8 1.2 8.9 3.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF972 PF06156.8 ETO04778.1 - 4.9 7.5 24.1 5.1 7.4 3.3 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Cortex-I_coil PF09304.5 ETO04778.1 - 5.3 7.1 25.6 4.4 7.3 9.3 2.8 1 1 2 3 3 3 0 Cortexillin I, coiled coil CENP-F_leu_zip PF10473.4 ETO04778.1 - 6.6 6.6 30.5 7.4 6.4 14.8 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Syntaxin-6_N PF09177.6 ETO04778.1 - 7.2 7.0 13.8 1.9e+03 -0.7 9.2 2.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF3552 PF12072.3 ETO04778.1 - 9.8 5.3 30.2 2 7.5 8.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Sigma70_ner PF04546.8 ETO04779.1 - 0.00057 19.5 1.7 0.00057 19.5 1.2 4.5 3 1 1 4 4 4 1 Sigma-70, non-essential region WD40 PF00400.27 ETO04780.1 - 3.5e-37 124.9 11.9 2.6e-11 42.9 0.0 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO04780.1 - 4.3e-10 38.3 2.4 0.0026 15.9 0.2 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO04780.1 - 0.00022 20.0 2.9 0.33 9.6 0.1 3.0 1 1 1 2 2 2 2 Nup133 N terminal like Kelch_6 PF13964.1 ETO04780.1 - 0.055 13.6 3.7 13 6.1 0.0 3.4 3 0 0 3 3 3 0 Kelch motif DEP PF00610.16 ETO04781.1 - 9.8e-16 57.2 0.2 1.5e-15 56.6 0.1 1.3 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RNA_binding PF01877.12 ETO04781.1 - 0.013 15.4 0.5 0.11 12.4 0.1 2.0 2 0 0 2 2 2 0 RNA binding Eco57I PF07669.6 ETO04783.1 - 0.11 12.8 1.2 0.42 10.9 0.2 2.1 1 1 1 2 2 2 0 Eco57I restriction-modification methylase Metallophos PF00149.23 ETO04784.1 - 6.2e-05 22.4 0.1 7.5e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CAP_GLY PF01302.20 ETO04787.1 - 2e-18 65.8 0.2 4.5e-18 64.7 0.1 1.6 1 0 0 1 1 1 1 CAP-Gly domain Phostensin_N PF13916.1 ETO04787.1 - 0.017 15.1 1.8 0.034 14.1 1.2 1.5 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal DUF465 PF04325.8 ETO04788.1 - 0.014 15.1 6.3 9 6.0 0.0 4.0 2 1 1 3 3 3 0 Protein of unknown function (DUF465) Med9 PF07544.8 ETO04788.1 - 0.017 14.8 16.3 0.023 14.4 5.4 3.8 2 2 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 ATG16 PF08614.6 ETO04788.1 - 9.4 5.9 34.5 23 4.7 14.8 3.8 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) Kinesin-relat_1 PF12711.2 ETO04788.1 - 9.9 6.6 22.7 2.2 8.7 9.6 2.8 1 1 1 2 2 2 0 Kinesin motor WD40 PF00400.27 ETO04789.1 - 3.4e-12 45.7 1.7 6.6e-05 22.6 0.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO04789.1 - 0.0066 14.6 0.3 0.37 8.8 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 zf-H2C2_2 PF13465.1 ETO04792.1 - 0.041 14.1 0.2 0.84 10.0 0.0 2.6 2 1 0 2 2 2 0 Zinc-finger double domain PH_10 PF15411.1 ETO04792.1 - 2.1 8.5 8.1 0.4 10.8 2.5 2.1 1 1 1 2 2 2 0 Pleckstrin homology domain PBP1_TM PF14812.1 ETO04793.1 - 0.077 13.3 5.3 0.19 12.0 3.7 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1180 PF06679.7 ETO04793.1 - 0.082 12.7 0.2 0.082 12.7 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) DUF506 PF04720.7 ETO04793.1 - 0.25 10.9 2.1 6.6 6.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF506) DUF605 PF04652.11 ETO04796.1 - 0.025 13.9 25.2 0.035 13.5 17.5 1.1 1 0 0 1 1 1 0 Vta1 like MIP-T3 PF10243.4 ETO04796.1 - 0.32 9.4 24.7 0.34 9.3 17.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Peptidase_S64 PF08192.6 ETO04796.1 - 1.7 6.9 14.7 2.3 6.4 10.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 BUD22 PF09073.5 ETO04796.1 - 2.3 7.2 25.3 3.1 6.7 17.6 1.3 1 0 0 1 1 1 0 BUD22 Ank_2 PF12796.2 ETO04797.1 - 7e-49 164.1 6.9 2.5e-20 72.5 0.2 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 ETO04797.1 - 3.6e-41 136.9 10.2 2.9e-07 29.9 0.2 8.3 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.1 ETO04797.1 - 8.4e-31 105.8 3.6 7.1e-08 32.7 0.0 6.8 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO04797.1 - 5.5e-30 102.7 11.4 4.1e-06 26.8 0.0 7.8 1 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO04797.1 - 1.8e-24 83.3 6.4 0.00036 20.5 0.1 8.8 9 0 0 9 9 9 6 Ankyrin repeat Ank PF00023.25 ETO04798.1 - 2.9e-06 26.8 0.6 9.8e-06 25.1 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 ETO04798.1 - 3.8e-06 27.1 0.0 5.8e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO04798.1 - 0.00013 22.1 0.0 0.00027 21.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO04798.1 - 0.00017 22.0 0.0 0.00062 20.2 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO04798.1 - 0.00085 19.3 0.1 0.0049 16.9 0.0 2.2 2 1 1 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 ETO04799.1 - 1.1e-12 48.1 0.8 1.8e-12 47.4 0.5 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO04799.1 - 2.6e-12 46.8 0.6 5.3e-07 29.9 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO04799.1 - 5.5e-10 39.1 3.0 4.5e-06 26.7 0.2 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 ETO04799.1 - 3.7e-08 32.7 3.6 0.00065 19.3 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 ETO04799.1 - 0.0052 16.9 1.3 0.98 9.8 0.1 2.8 2 0 0 2 2 2 1 Ankyrin repeat Galanin PF01296.13 ETO04799.1 - 0.28 11.0 1.6 2.1 8.2 0.0 2.8 3 0 0 3 3 3 0 Galanin RGS PF00615.14 ETO04800.1 - 0.039 14.0 0.1 0.07 13.2 0.0 1.4 1 0 0 1 1 1 0 Regulator of G protein signaling domain Kelch_2 PF07646.10 ETO04801.1 - 0.0021 17.7 0.1 0.0056 16.3 0.0 1.7 2 0 0 2 2 2 1 Kelch motif DUF2207 PF09972.4 ETO04801.1 - 0.0046 15.6 0.4 0.0073 14.9 0.3 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) PH_5 PF15405.1 ETO04801.1 - 0.032 14.1 3.4 0.1 12.5 2.4 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain BPL_N PF09825.4 ETO04801.1 - 0.11 11.2 2.7 0.15 10.8 1.9 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Consortin_C PF15281.1 ETO04801.1 - 0.11 11.9 6.4 0.067 12.6 1.8 2.5 2 1 0 2 2 2 0 Consortin C-terminus A_deaminase PF00962.17 ETO04802.1 - 0.00022 20.2 0.0 0.00022 20.2 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase SprA-related PF12118.3 ETO04803.1 - 0.8 8.9 20.2 0.96 8.7 14.0 1.0 1 0 0 1 1 1 0 SprA-related family Herpes_DNAp_acc PF04929.7 ETO04803.1 - 1.4 7.7 14.7 1.7 7.5 10.2 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Membralin PF09746.4 ETO04803.1 - 2.2 7.2 5.8 2.5 7.0 4.0 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF2981 PF11200.3 ETO04803.1 - 2.3 7.1 14.0 2.5 7.0 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Pneumo_att_G PF05539.6 ETO04803.1 - 4.2 6.6 16.2 5 6.4 11.2 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G MAP65_ASE1 PF03999.7 ETO04803.1 - 6.3 5.2 21.9 7.4 5.0 15.2 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Nucleoplasmin PF03066.10 ETO04804.1 - 0.0082 15.6 9.2 0.012 15.1 6.4 1.2 1 0 0 1 1 1 1 Nucleoplasmin AF1Q PF15017.1 ETO04804.1 - 0.048 13.5 5.2 0.079 12.8 3.6 1.3 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator DNA_pol3_a_NII PF11490.3 ETO04804.1 - 0.13 11.8 6.0 0.18 11.3 4.2 1.1 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II TRAP_alpha PF03896.11 ETO04804.1 - 0.15 11.0 2.6 0.16 10.9 1.8 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FAM176 PF14851.1 ETO04804.1 - 0.16 11.6 2.0 0.23 11.1 1.4 1.4 1 0 0 1 1 1 0 FAM176 family Sigma70_ner PF04546.8 ETO04804.1 - 0.53 9.8 6.7 0.6 9.6 4.7 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Radial_spoke PF04712.7 ETO04804.1 - 0.66 8.6 9.4 0.92 8.1 6.5 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein DUF3682 PF12446.3 ETO04804.1 - 0.71 10.1 9.4 1.1 9.5 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DUF4448 PF14610.1 ETO04804.1 - 0.73 9.2 6.6 1.7 8.1 4.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) Adeno_terminal PF02459.10 ETO04804.1 - 0.82 7.7 5.2 0.94 7.5 3.6 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Prp19_bind PF06991.6 ETO04804.1 - 1.4 8.1 10.0 1.8 7.7 7.0 1.1 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain DUF3377 PF11857.3 ETO04804.1 - 2 8.1 7.2 4.2 7.0 5.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) TFIIF_alpha PF05793.7 ETO04804.1 - 2.2 6.5 8.2 2.5 6.3 5.7 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 ETO04804.1 - 3.1 5.6 8.3 3.5 5.4 5.8 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2890 PF11081.3 ETO04804.1 - 3.2 7.7 9.9 3.8 7.5 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) SDA1 PF05285.7 ETO04804.1 - 3.2 6.9 8.1 3.6 6.7 5.6 1.0 1 0 0 1 1 1 0 SDA1 Myc_N PF01056.13 ETO04804.1 - 3.9 6.5 11.3 4.7 6.2 7.8 1.1 1 0 0 1 1 1 0 Myc amino-terminal region HSP90 PF00183.13 ETO04804.1 - 4.8 5.4 8.5 6.1 5.1 5.9 1.1 1 0 0 1 1 1 0 Hsp90 protein BMF PF15185.1 ETO04804.1 - 5.2 6.2 5.9 7 5.8 4.1 1.1 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis VID27 PF08553.5 ETO04804.1 - 5.4 5.0 8.3 6.6 4.8 5.8 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Daxx PF03344.10 ETO04804.1 - 7.7 4.8 12.0 8.6 4.7 8.3 1.0 1 0 0 1 1 1 0 Daxx Family YcxB PF14317.1 ETO04805.1 - 0.12 11.6 0.1 0.34 10.1 0.0 1.8 2 0 0 2 2 2 0 YcxB-like protein PUB PF09409.5 ETO04806.1 - 0.0011 18.6 0.8 0.01 15.5 0.6 2.5 1 1 0 1 1 1 1 PUB domain AAA_24 PF13479.1 ETO04806.1 - 0.067 12.7 1.8 0.58 9.7 0.2 2.2 1 1 1 2 2 2 0 AAA domain Folate_rec PF03024.9 ETO04806.1 - 0.37 10.3 3.0 2 7.9 0.0 2.3 2 1 0 2 2 2 0 Folate receptor family TnpV PF14198.1 ETO04807.1 - 0.072 12.9 0.2 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Transposon-encoded protein TnpV SHS2_Rpb7-N PF03876.12 ETO04809.1 - 0.057 13.5 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Usp PF00582.21 ETO04810.1 - 0.00025 21.2 0.1 0.00046 20.3 0.0 1.4 1 0 0 1 1 1 1 Universal stress protein family Usp PF00582.21 ETO04811.1 - 1.4e-17 64.1 0.0 1.5e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family CbiX PF01903.12 ETO04811.1 - 0.12 12.5 0.0 4.4 7.4 0.0 2.1 1 1 1 2 2 2 0 CbiX Exo_endo_phos_2 PF14529.1 ETO04812.1 - 6.6e-10 38.6 0.1 1.2e-09 37.8 0.1 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Sec31 PF11549.3 ETO04812.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein transport protein SEC31 Tic20 PF09685.5 ETO04813.1 - 0.024 14.6 2.2 0.046 13.7 1.5 1.5 1 0 0 1 1 1 0 Tic20-like protein DUF3413 PF11893.3 ETO04813.1 - 0.035 13.0 7.7 0.99 8.2 3.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3413) Closter_coat PF01785.12 ETO04814.1 - 0.027 13.5 0.2 0.071 12.1 0.1 1.9 1 1 0 1 1 1 0 Closterovirus coat protein Dynein_light PF01221.13 ETO04815.1 - 1.2e-33 114.9 6.3 7.6e-33 112.3 4.4 1.9 1 1 0 1 1 1 1 Dynein light chain type 1 DUF3796 PF12676.2 ETO04815.1 - 8.4 6.6 11.1 1.1 9.5 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3796) Cpn60_TCP1 PF00118.19 ETO04817.1 - 2.9e-32 111.9 0.7 6.9e-32 110.6 0.5 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family PG_binding_2 PF08823.6 ETO04818.1 - 0.078 13.0 1.0 0.13 12.4 0.7 1.5 1 1 0 1 1 1 0 Putative peptidoglycan binding domain CPSF73-100_C PF11718.3 ETO04818.1 - 1 8.6 7.1 1.1 8.5 4.9 1.0 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term RPEL PF02755.10 ETO04819.1 - 0.0011 18.2 1.2 0.0035 16.6 0.8 2.0 1 0 0 1 1 1 1 RPEL repeat Tropomyosin_1 PF12718.2 ETO04820.1 - 0.0014 18.4 4.4 0.0014 18.4 3.0 2.2 2 0 0 2 2 2 1 Tropomyosin like Microtub_assoc PF07989.6 ETO04820.1 - 0.0066 16.2 3.2 0.0066 16.2 2.2 2.4 2 0 0 2 2 2 1 Microtubule associated CCDC155 PF14662.1 ETO04820.1 - 0.0067 16.0 9.8 0.018 14.6 4.3 2.1 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 DUF1227 PF06777.6 ETO04820.1 - 0.013 15.2 2.4 0.019 14.6 1.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1227) Mod_r PF07200.8 ETO04820.1 - 0.013 15.3 3.2 0.013 15.3 2.2 2.0 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Lzipper-MIP1 PF14389.1 ETO04820.1 - 0.013 15.5 1.5 0.013 15.5 1.0 2.8 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DUF496 PF04363.7 ETO04820.1 - 0.026 14.3 1.7 0.026 14.3 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF496) DivIC PF04977.10 ETO04820.1 - 0.06 12.8 12.2 0.68 9.4 0.7 3.3 2 1 1 3 3 3 0 Septum formation initiator Sec2p PF06428.6 ETO04820.1 - 0.074 12.9 6.7 0.11 12.3 2.4 2.4 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p Allexi_40kDa PF05549.6 ETO04820.1 - 0.094 11.9 1.7 0.089 12.0 0.8 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein DUF2353 PF09789.4 ETO04820.1 - 0.15 11.2 6.0 0.036 13.3 1.6 1.8 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) TMF_DNA_bd PF12329.3 ETO04820.1 - 0.16 11.7 16.7 0.4 10.5 5.5 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding KLRAQ PF10205.4 ETO04820.1 - 0.22 11.6 9.8 0.056 13.4 4.5 1.8 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein Tropomyosin PF00261.15 ETO04820.1 - 0.22 10.5 13.5 0.025 13.6 4.6 2.0 2 0 0 2 2 2 0 Tropomyosin Myosin_tail_1 PF01576.14 ETO04820.1 - 0.24 9.0 9.2 0.078 10.6 3.8 1.8 2 0 0 2 2 2 0 Myosin tail Seryl_tRNA_N PF02403.17 ETO04820.1 - 0.29 11.1 6.6 0.064 13.2 1.9 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Macoilin PF09726.4 ETO04820.1 - 0.33 9.1 7.0 1.1 7.4 2.0 2.0 1 1 1 2 2 2 0 Transmembrane protein ATG16 PF08614.6 ETO04820.1 - 0.35 10.6 9.6 1.6 8.4 6.6 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.4 ETO04820.1 - 0.46 10.6 7.2 0.54 10.4 1.2 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Zwint PF15556.1 ETO04820.1 - 0.47 9.6 5.2 0.11 11.7 1.3 1.6 2 0 0 2 2 2 0 ZW10 interactor Tnp_P_element PF12017.3 ETO04820.1 - 0.47 9.6 4.1 0.51 9.5 0.8 1.9 2 0 0 2 2 2 0 Transposase protein IncA PF04156.9 ETO04820.1 - 0.62 9.6 10.6 0.92 9.0 4.2 2.0 1 1 1 2 2 2 0 IncA protein ADIP PF11559.3 ETO04820.1 - 0.67 9.8 9.9 0.13 12.1 3.4 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Rootletin PF15035.1 ETO04820.1 - 0.86 9.5 7.6 1.4 8.9 3.4 2.0 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Jnk-SapK_ap_N PF09744.4 ETO04820.1 - 0.91 9.5 9.4 0.17 11.8 2.8 1.9 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Snapin_Pallidin PF14712.1 ETO04820.1 - 1.5 9.2 12.5 0.26 11.6 4.3 2.1 2 0 0 2 2 2 0 Snapin/Pallidin Cep57_CLD PF14073.1 ETO04820.1 - 2 8.2 9.1 1.5 8.5 3.6 2.0 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 Cut12 PF11500.3 ETO04820.1 - 2.4 7.8 6.3 0.31 10.7 1.3 1.9 2 1 0 2 2 2 0 Spindle pole body formation-associated protein CENP-F_leu_zip PF10473.4 ETO04820.1 - 2.4 8.0 11.0 0.58 10.0 4.3 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.5 ETO04820.1 - 3.4 7.8 7.2 1.2 9.2 0.6 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF972 PF06156.8 ETO04820.1 - 3.4 8.0 12.1 0.89 9.9 3.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF972) CENP-H PF05837.7 ETO04820.1 - 3.6 7.8 8.2 1.3 9.2 2.0 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF904 PF06005.7 ETO04820.1 - 3.6 7.9 17.8 5.9 7.2 6.6 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF904) HOOK PF05622.7 ETO04820.1 - 3.7 5.2 11.0 1.4 6.5 3.5 2.0 1 1 0 2 2 2 0 HOOK protein Lipoprotein_20 PF13942.1 ETO04820.1 - 3.8 7.0 7.3 2.4 7.6 0.1 2.1 2 0 0 2 2 2 0 YfhG lipoprotein Uso1_p115_C PF04871.8 ETO04820.1 - 4.6 7.1 9.6 32 4.4 6.7 2.3 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1832 PF08870.6 ETO04821.1 - 0.023 14.3 1.3 0.039 13.6 0.7 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1832) Ank_3 PF13606.1 ETO04822.1 - 0.019 15.1 0.1 0.78 10.1 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeat NMT_C PF02799.10 ETO04822.1 - 0.041 13.2 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Ank_2 PF12796.2 ETO04822.1 - 0.065 13.5 0.1 1.8 8.9 0.0 2.1 1 1 0 2 2 2 0 Ankyrin repeats (3 copies) Ank PF00023.25 ETO04822.1 - 0.12 12.1 0.0 5.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat Apis_Csd PF11671.3 ETO04823.1 - 0.039 13.7 7.6 0.067 12.9 5.3 1.4 1 0 0 1 1 1 0 Complementary sex determiner protein T4_Gp59_N PF08993.5 ETO04824.1 - 0.075 13.0 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase SGL PF08450.7 ETO04825.1 - 5.4e-09 35.7 0.0 7.5e-08 32.0 0.0 2.6 1 1 1 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 ETO04825.1 - 0.00012 21.8 3.3 2.5 8.2 0.0 4.9 5 0 0 5 5 5 3 NHL repeat Ribosomal_S20p PF01649.13 ETO04826.1 - 0.073 13.4 2.6 0.26 11.7 1.8 1.9 1 0 0 1 1 1 0 Ribosomal protein S20 Lipase_GDSL PF00657.17 ETO04827.1 - 0.041 13.7 1.2 0.042 13.6 0.8 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase DUF4337 PF14235.1 ETO04827.1 - 4 7.2 6.4 4.9 6.9 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Abhydrolase_5 PF12695.2 ETO04828.1 - 2.6e-15 56.4 0.0 2.1e-14 53.5 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETO04828.1 - 1.7e-07 31.3 0.0 0.0013 18.6 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 ETO04828.1 - 0.0093 15.4 0.3 1.5 8.1 0.0 2.6 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 ETO04828.1 - 0.01 15.4 0.0 2.9 7.3 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold NOA36 PF06524.7 ETO04828.1 - 0.016 14.5 9.8 0.023 13.9 6.8 1.2 1 0 0 1 1 1 0 NOA36 protein Peptidase_S9 PF00326.16 ETO04828.1 - 0.067 12.3 0.0 0.84 8.8 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family HeH PF12949.2 ETO04828.1 - 0.085 12.4 0.3 0.2 11.2 0.2 1.5 1 0 0 1 1 1 0 HeH/LEM domain FSH1 PF03959.8 ETO04828.1 - 0.11 11.9 0.1 0.7 9.2 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Nop14 PF04147.7 ETO04828.1 - 0.16 9.8 11.3 0.2 9.5 7.8 1.1 1 0 0 1 1 1 0 Nop14-like family LIP PF03583.9 ETO04828.1 - 0.17 11.0 0.0 3.7 6.6 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase CDC45 PF02724.9 ETO04828.1 - 0.21 9.5 10.0 0.28 9.1 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.6 ETO04828.1 - 5.7 4.9 7.7 7.9 4.4 5.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NICE-3 PF07406.6 ETO04829.1 - 0.052 13.0 0.6 0.07 12.6 0.4 1.2 1 0 0 1 1 1 0 NICE-3 protein PAXNEB PF05625.6 ETO04829.1 - 0.19 10.5 2.7 0.17 10.7 0.7 1.6 1 1 1 2 2 2 0 PAXNEB protein DUF3931 PF13082.1 ETO04829.1 - 0.38 10.6 0.3 0.38 10.6 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3931) DUF896 PF05979.7 ETO04830.1 - 0.036 13.6 0.2 0.1 12.1 0.1 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) Hydrolase_6 PF13344.1 ETO04830.1 - 0.29 11.0 3.0 0.41 10.5 1.3 1.9 1 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase WD40 PF00400.27 ETO04831.1 - 2.8e-12 45.9 4.7 0.00015 21.5 0.0 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO04831.1 - 0.1 10.6 0.2 0.57 8.2 0.0 1.9 2 0 0 2 2 2 0 Nucleoporin Nup120/160 SK_channel PF03530.9 ETO04831.1 - 0.33 10.7 3.2 4 7.3 0.0 2.2 2 0 0 2 2 2 0 Calcium-activated SK potassium channel WD40 PF00400.27 ETO04835.1 - 2.1e-06 27.4 0.5 0.00027 20.6 0.3 2.3 2 1 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO04835.1 - 0.021 12.9 0.0 0.021 12.9 0.0 1.0 1 0 0 1 1 1 0 Nucleoporin Nup120/160 WD40 PF00400.27 ETO04837.1 - 2.7e-10 39.7 1.1 9.5e-09 34.8 0.5 2.6 3 0 0 3 3 3 1 WD domain, G-beta repeat Arg_repressor PF01316.16 ETO04837.1 - 0.058 12.9 0.1 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain DUF924 PF06041.6 ETO04839.1 - 2.3e-55 187.2 2.1 4.6e-55 186.2 1.5 1.5 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Peptidase_M15 PF01427.12 ETO04839.1 - 5.6e-37 127.2 0.2 7.3e-34 117.1 0.0 2.3 1 1 1 2 2 2 2 D-ala-D-ala dipeptidase VanY PF02557.12 ETO04839.1 - 0.0059 16.4 0.3 0.028 14.2 0.0 2.1 2 0 0 2 2 2 1 D-alanyl-D-alanine carboxypeptidase GcpE PF04551.9 ETO04840.1 - 1.3e-08 34.0 0.0 2e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 GcpE protein Imm29 PF15575.1 ETO04841.1 - 0.027 14.1 0.0 0.072 12.6 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 29 Het-C PF07217.6 ETO04841.1 - 4.1 5.4 10.3 0.055 11.6 1.2 1.8 2 0 0 2 2 2 0 Heterokaryon incompatibility protein Het-C DUF502 PF04367.8 ETO04842.1 - 0.0071 16.1 0.0 0.023 14.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF502) Ank_5 PF13857.1 ETO04843.1 - 4.9e-06 26.6 0.1 0.0023 18.1 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO04843.1 - 0.00029 21.2 0.5 0.01 16.3 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO04843.1 - 0.0036 17.5 0.0 0.005 17.1 0.0 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO04843.1 - 0.007 16.1 0.2 0.031 14.0 0.0 2.2 2 1 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 ETO04843.1 - 0.048 13.9 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeat DNA_pol_B_2 PF03175.8 ETO04843.1 - 0.087 11.4 0.3 0.09 11.4 0.2 1.0 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral Ank_2 PF12796.2 ETO04844.1 - 1.3e-07 31.7 0.0 3.6e-06 27.2 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO04844.1 - 1.7e-06 28.3 0.0 0.00029 21.2 0.0 2.8 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 ETO04844.1 - 2.2e-06 27.1 0.0 0.007 16.1 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 ETO04844.1 - 0.0021 18.2 0.0 0.24 11.7 0.0 2.6 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO04844.1 - 0.038 14.2 0.0 12 6.5 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeat Peptidase_C14 PF00656.17 ETO04845.1 - 2.6e-11 43.7 0.3 5.9e-11 42.5 0.2 1.5 1 1 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.17 ETO04846.1 - 0.00092 18.9 1.0 0.0017 18.0 0.7 1.4 1 1 0 1 1 1 1 Caspase domain DUF1514 PF07438.6 ETO04846.1 - 8.4 6.3 10.2 0.14 12.0 0.3 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1514) Kelch_6 PF13964.1 ETO04848.1 - 0.00039 20.4 3.9 0.66 10.2 0.0 4.2 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO04848.1 - 0.087 12.3 4.0 1.2 8.7 0.3 3.7 4 0 0 4 4 4 0 Kelch motif CTNNBL PF08216.6 ETO04848.1 - 0.54 9.8 5.1 3.1 7.4 0.7 2.4 2 0 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear Kelch_2 PF07646.10 ETO04849.1 - 0.058 13.1 2.0 32 4.4 0.1 4.1 4 0 0 4 4 4 0 Kelch motif RelA_SpoT PF04607.12 ETO04850.1 - 0.00064 19.7 1.7 0.00064 19.7 1.2 2.1 1 1 1 2 2 2 1 Region found in RelA / SpoT proteins Ctf8 PF09696.5 ETO04850.1 - 0.061 13.1 0.2 0.18 11.6 0.1 2.0 1 1 1 2 2 2 0 Ctf8 WD40 PF00400.27 ETO04851.1 - 1.2e-16 59.9 1.5 6.2e-09 35.3 0.0 3.8 3 1 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO04851.1 - 0.00036 18.8 0.0 0.22 9.6 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO04851.1 - 0.0061 15.3 1.1 0.015 14.0 0.5 1.9 1 1 1 2 2 2 1 Nup133 N terminal like FPL PF09758.4 ETO04852.1 - 0.00015 21.5 2.9 0.073 12.8 0.3 2.5 1 1 1 2 2 2 2 Uncharacterised conserved protein UPF0223 PF05256.7 ETO04852.1 - 0.00038 20.5 0.9 0.15 12.1 0.0 2.5 1 1 2 3 3 3 2 Uncharacterised protein family (UPF0223) IPK PF03770.11 ETO04852.1 - 0.036 13.6 0.8 0.2 11.2 0.2 1.8 1 1 1 2 2 2 0 Inositol polyphosphate kinase HAUS4 PF14735.1 ETO04852.1 - 0.041 13.1 3.3 0.035 13.4 1.3 1.5 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 4 DUF3600 PF12207.3 ETO04852.1 - 0.075 12.5 0.4 3.7 7.0 0.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3600) PRMT5 PF05185.11 ETO04852.1 - 0.13 11.1 0.9 0.18 10.7 0.7 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_16 PF10294.4 ETO04853.1 - 0.053 12.9 1.4 0.065 12.6 0.8 1.4 1 1 0 1 1 1 0 Putative methyltransferase CBM_3 PF00942.13 ETO04853.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Cellulose binding domain UCH PF00443.24 ETO04854.1 - 7.2e-48 163.0 1.8 7.2e-48 163.0 1.2 2.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO04854.1 - 5.8e-29 101.4 0.3 5.8e-29 101.4 0.2 2.8 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Imm42 PF15601.1 ETO04854.1 - 0.011 15.1 0.0 0.029 13.7 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 42 Peptidase_C14 PF00656.17 ETO04855.1 - 5.3e-09 36.1 0.2 5.3e-09 36.1 0.1 2.1 3 0 0 3 3 3 1 Caspase domain Kelch_6 PF13964.1 ETO04855.1 - 1.3e-05 25.1 7.7 0.011 15.8 0.1 4.7 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.20 ETO04855.1 - 3.3e-05 23.3 11.4 0.01 15.3 0.2 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO04855.1 - 0.00052 19.6 9.5 0.006 16.3 0.1 5.7 6 0 0 6 6 6 1 Kelch motif Kelch_4 PF13418.1 ETO04855.1 - 0.009 15.7 1.1 6.2 6.6 0.0 3.4 3 0 0 3 3 3 1 Galactose oxidase, central domain UL11 PF11094.3 ETO04855.1 - 0.059 13.1 0.0 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 Membrane-associated tegument protein Kelch_5 PF13854.1 ETO04855.1 - 0.11 12.4 0.9 8.4 6.4 0.0 3.0 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.1 ETO04855.1 - 0.11 12.6 2.0 0.91 9.7 0.0 3.2 4 0 0 4 4 4 0 Galactose oxidase, central domain Suc_Fer-like PF06999.7 ETO04855.1 - 0.57 10.1 9.4 8.3 6.3 0.0 3.4 3 0 0 3 3 3 0 Sucrase/ferredoxin-like FAM176 PF14851.1 ETO04855.1 - 5.4 6.6 12.2 16 5.1 8.4 1.8 1 0 0 1 1 1 0 FAM176 family Methyltrn_RNA_4 PF09936.4 ETO04857.1 - 0.12 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase DUF4245 PF14030.1 ETO04858.1 - 0.36 10.5 5.4 0.6 9.8 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) CENP-B_dimeris PF09026.5 ETO04859.1 - 0.0026 17.9 1.9 0.0026 17.9 1.3 3.3 1 1 2 3 3 3 2 Centromere protein B dimerisation domain Mak16 PF04874.9 ETO04859.1 - 0.029 14.4 4.1 0.029 14.4 2.8 3.3 2 1 1 3 3 3 0 Mak16 protein C-terminal region Ribosomal_60s PF00428.14 ETO04859.1 - 0.032 14.6 7.7 0.032 14.6 5.4 3.1 3 1 0 3 3 3 0 60s Acidic ribosomal protein Conotoxin PF02950.12 ETO04859.1 - 2.5 8.9 8.6 5.4 7.8 0.0 3.2 3 0 0 3 3 3 0 Conotoxin WD40 PF00400.27 ETO04860.1 - 9.1e-08 31.7 0.1 9.1e-08 31.7 0.1 2.8 4 0 0 4 4 4 1 WD domain, G-beta repeat WD40 PF00400.27 ETO04861.1 - 3.4e-23 80.6 1.6 7e-11 41.5 0.0 3.5 3 1 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO04861.1 - 0.016 13.3 0.1 0.037 12.1 0.0 1.5 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Rav1p_C PF12234.3 ETO04862.1 - 5.5e-45 153.6 9.8 1.1e-44 152.7 6.8 1.4 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 ETO04863.1 - 2.4e-80 261.8 10.3 7.1e-12 44.7 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO04863.1 - 3.6e-09 36.6 0.0 0.0009 19.0 0.0 3.3 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO04863.1 - 3.8e-07 29.6 4.4 1.7 8.3 0.0 6.2 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 ETO04863.1 - 7.6e-07 28.5 1.9 1.7 7.6 0.0 5.1 1 1 3 5 5 5 3 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 ETO04863.1 - 6.1e-06 24.6 7.7 0.067 11.3 0.5 4.4 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO04863.1 - 1.8e-05 23.7 4.3 0.26 10.0 0.1 5.0 1 1 3 4 4 4 2 Nup133 N terminal like Gmad1 PF10647.4 ETO04863.1 - 0.0012 18.3 0.0 0.036 13.4 0.0 2.2 2 0 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain Cytochrom_D1 PF02239.11 ETO04863.1 - 0.0014 17.0 0.0 0.92 7.7 0.0 3.0 1 1 1 3 3 3 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO04863.1 - 0.0054 16.2 0.1 0.92 8.9 0.0 2.3 2 0 0 2 2 2 1 PQQ-like domain DUF3312 PF11768.3 ETO04863.1 - 0.011 13.9 0.1 0.95 7.6 0.0 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3312) Proteasome_A_N PF10584.4 ETO04863.1 - 0.015 14.6 15.6 3 7.2 0.1 6.0 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature Apc4_WD40 PF12894.2 ETO04863.1 - 0.026 14.0 0.0 8.1 6.0 0.0 3.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain bZIP_2 PF07716.10 ETO04864.1 - 0.15 11.9 0.3 0.15 11.9 0.2 2.8 3 0 0 3 3 3 0 Basic region leucine zipper EMP24_GP25L PF01105.19 ETO04865.1 - 0.0015 18.2 0.9 0.0021 17.8 0.7 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PDZ_2 PF13180.1 ETO04865.1 - 0.0071 16.2 0.1 0.013 15.3 0.1 1.5 1 0 0 1 1 1 1 PDZ domain DUF2859 PF11072.3 ETO04865.1 - 0.081 12.3 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2859) WBS_methylT PF12589.3 ETO04866.1 - 0.048 14.1 4.5 0.068 13.6 3.1 1.2 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome CDC45 PF02724.9 ETO04866.1 - 0.18 9.7 13.3 0.2 9.6 9.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 ETO04866.1 - 0.21 10.0 16.2 0.23 9.9 11.2 1.0 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 ETO04866.1 - 1.3 7.7 27.5 1.5 7.4 19.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TRAP_alpha PF03896.11 ETO04866.1 - 1.4 7.8 7.1 1.5 7.7 4.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Osteopontin PF00865.13 ETO04866.1 - 1.5 7.9 22.8 1.7 7.7 15.8 1.1 1 0 0 1 1 1 0 Osteopontin NOA36 PF06524.7 ETO04866.1 - 1.7 7.8 14.5 2.1 7.5 10.0 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 ETO04866.1 - 1.7 6.4 20.9 2 6.2 14.5 1.0 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.7 ETO04866.1 - 2.7 6.2 19.9 3.1 6.0 13.8 1.0 1 0 0 1 1 1 0 Mpp10 protein Vfa1 PF08432.5 ETO04866.1 - 3.3 7.7 7.6 4.5 7.2 5.3 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Sporozoite_P67 PF05642.6 ETO04866.1 - 4.3 5.0 10.3 4.9 4.8 7.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen YL1 PF05764.8 ETO04866.1 - 4.7 6.7 15.8 5.7 6.4 11.0 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Dynein_heavy PF03028.10 ETO04867.1 - 1.7e-146 489.1 0.3 2.2e-146 488.7 0.2 1.0 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor PilI PF10623.4 ETO04867.1 - 0.039 13.8 0.0 0.75 9.7 0.0 2.4 2 0 0 2 2 2 0 Plasmid conjugative transfer protein PilI Ima1_N PF09779.4 ETO04867.1 - 0.067 13.6 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Ima1 N-terminal domain AAA_9 PF12781.2 ETO04868.1 - 3.8e-48 163.2 3.9 6.4e-47 159.3 0.2 2.3 2 0 0 2 2 2 2 ATP-binding dynein motor region D5 MT PF12777.2 ETO04868.1 - 5.5e-40 137.1 3.1 8.5e-40 136.5 2.2 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.10 ETO04868.1 - 8.3e-11 40.6 6.5 1.3e-10 39.9 0.1 3.3 4 0 0 4 4 4 1 Dynein heavy chain and region D6 of dynein motor Laminin_II PF06009.7 ETO04868.1 - 0.0052 16.5 2.5 0.0052 16.5 1.7 2.2 2 1 0 2 2 2 1 Laminin Domain II PRF PF06875.6 ETO04868.1 - 0.065 12.4 0.3 0.14 11.3 0.2 1.5 1 0 0 1 1 1 0 Plethodontid receptivity factor PRF DUF4164 PF13747.1 ETO04868.1 - 0.67 10.1 10.7 0.033 14.3 2.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) TMF_DNA_bd PF12329.3 ETO04868.1 - 2.8 7.7 19.0 0.13 12.0 7.6 2.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF342 PF03961.8 ETO04868.1 - 6.1 5.1 10.0 0.88 7.9 2.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) AAA_8 PF12780.2 ETO04869.1 - 9.1e-66 221.5 0.2 1.9e-65 220.5 0.1 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_6 PF12774.2 ETO04869.1 - 1.9e-62 210.8 0.8 4.4e-60 203.0 0.2 3.3 2 1 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_7 PF12775.2 ETO04869.1 - 2.8e-41 141.3 0.2 1.1e-40 139.5 0.1 2.1 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 ETO04869.1 - 1.1e-14 54.3 1.5 0.00023 20.8 0.0 5.7 6 0 0 6 6 6 3 AAA domain (dynein-related subfamily) AAA PF00004.24 ETO04869.1 - 1.7e-05 25.0 1.6 0.049 13.8 0.0 4.4 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETO04869.1 - 0.0014 18.7 4.4 0.94 9.6 0.0 5.0 4 1 0 4 4 4 1 AAA domain AAA_30 PF13604.1 ETO04869.1 - 0.0025 17.4 0.4 0.29 10.7 0.2 2.6 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 ETO04869.1 - 0.023 13.5 1.4 0.085 11.7 0.1 2.6 3 0 0 3 3 3 0 Type II/IV secretion system protein UPF0079 PF02367.12 ETO04869.1 - 0.055 13.1 1.6 2.7 7.6 0.1 3.3 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 ETO04869.1 - 0.056 13.4 6.1 5.4 6.9 0.0 4.7 4 1 0 4 4 4 0 AAA ATPase domain AAA_19 PF13245.1 ETO04869.1 - 0.059 13.1 0.2 0.19 11.4 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 ETO04869.1 - 0.086 13.0 6.1 6.1 7.0 0.0 5.0 6 0 0 6 6 6 0 RNA helicase AAA_18 PF13238.1 ETO04869.1 - 0.19 12.0 3.6 6.7 7.0 0.1 3.9 4 0 0 4 4 4 0 AAA domain DHC_N2 PF08393.8 ETO04870.1 - 8.2e-57 192.5 8.7 8.2e-57 192.5 6.0 3.6 3 1 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 WD40 PF00400.27 ETO04871.1 - 5.1e-73 238.5 10.7 7.2e-13 47.8 0.3 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO04871.1 - 1.4e-13 50.9 0.2 0.00055 19.6 0.0 4.5 1 1 4 5 5 5 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO04871.1 - 5.8e-10 38.6 6.2 0.11 12.1 0.0 7.2 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO04871.1 - 9.8e-08 31.1 3.5 0.18 10.5 0.0 4.4 1 1 2 4 4 4 3 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO04871.1 - 1.3e-06 27.0 0.2 0.0036 15.6 0.0 3.0 2 2 2 4 4 4 3 Cytochrome D1 heme domain Nup160 PF11715.3 ETO04871.1 - 0.00013 20.2 0.5 3.6 5.5 0.0 4.1 1 1 1 3 3 3 2 Nucleoporin Nup120/160 B_lectin PF01453.19 ETO04871.1 - 0.00044 20.0 0.5 3.2 7.6 0.0 3.8 2 1 2 4 4 4 1 D-mannose binding lectin DUF1258 PF06869.7 ETO04871.1 - 0.00062 18.9 0.1 0.061 12.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1258) PQQ_2 PF13360.1 ETO04871.1 - 0.0086 15.5 0.0 0.044 13.2 0.0 2.1 1 1 0 1 1 1 1 PQQ-like domain Mid2 PF04478.7 ETO04871.1 - 0.0094 15.3 1.3 7.6 5.9 0.0 3.6 3 1 1 4 4 4 2 Mid2 like cell wall stress sensor Nbas_N PF15492.1 ETO04871.1 - 0.037 13.1 0.3 4.9 6.1 0.0 3.9 2 1 2 5 5 5 0 Neuroblastoma-amplified sequence, N terminal DPPIV_N PF00930.16 ETO04871.1 - 0.1 11.1 0.1 24 3.3 0.0 3.6 2 1 3 5 5 5 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Proteasome_A_N PF10584.4 ETO04871.1 - 4.3 6.7 0.0 4.3 6.7 0.0 5.1 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature IATP PF04568.7 ETO04872.1 - 0.1 12.6 3.2 0.14 12.2 2.2 1.3 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP DUF3019 PF11456.3 ETO04872.1 - 0.13 12.6 0.8 0.38 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3019) WD40 PF00400.27 ETO04873.1 - 1.3e-12 47.0 1.5 0.0033 17.2 0.2 3.7 3 1 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO04873.1 - 0.042 11.9 0.0 0.21 9.7 0.0 1.7 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO04873.1 - 0.083 11.6 1.0 4.5 5.9 0.1 2.2 1 1 1 2 2 2 0 Nup133 N terminal like DUF2439 PF10382.4 ETO04874.1 - 0.0064 16.6 1.0 0.0097 16.0 0.4 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2439) VirE PF05272.6 ETO04875.1 - 0.024 14.0 5.1 0.027 13.9 3.5 1.0 1 0 0 1 1 1 0 Virulence-associated protein E DUF1311 PF07007.7 ETO04875.1 - 0.029 14.4 4.3 0.032 14.3 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1311) DUF1759 PF03564.10 ETO04875.1 - 0.042 13.6 4.4 0.063 13.0 2.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) Cytochrom_B562 PF07361.6 ETO04875.1 - 0.063 13.7 6.5 0.073 13.4 4.5 1.1 1 0 0 1 1 1 0 Cytochrome b562 DUF4515 PF14988.1 ETO04875.1 - 0.074 12.7 14.8 0.073 12.7 10.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) IL6 PF00489.12 ETO04875.1 - 0.077 12.5 3.1 0.085 12.4 2.2 1.2 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family AAA_35 PF14516.1 ETO04875.1 - 0.11 11.1 2.8 0.11 11.0 2.0 1.0 1 0 0 1 1 1 0 AAA-like domain Fib_alpha PF08702.5 ETO04875.1 - 0.11 12.5 9.5 0.12 12.5 6.6 1.0 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.7 ETO04875.1 - 0.18 11.5 14.9 0.22 11.2 10.4 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF501 PF04417.7 ETO04875.1 - 0.19 11.5 3.4 0.28 11.0 2.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF501) Laminin_II PF06009.7 ETO04875.1 - 0.2 11.4 5.6 0.25 11.1 3.9 1.3 1 0 0 1 1 1 0 Laminin Domain II ERO1 PF04137.10 ETO04875.1 - 0.29 10.1 6.7 0.31 10.0 4.6 1.0 1 0 0 1 1 1 0 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) KapB PF08810.5 ETO04875.1 - 0.34 10.9 4.5 0.43 10.6 3.1 1.2 1 0 0 1 1 1 0 Kinase associated protein B Seryl_tRNA_N PF02403.17 ETO04875.1 - 0.35 10.8 12.1 0.69 9.9 8.4 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain EAP30 PF04157.11 ETO04875.1 - 0.4 9.7 9.1 0.43 9.7 6.3 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family Retrotrans_gag PF03732.12 ETO04875.1 - 0.42 10.7 6.7 0.6 10.2 4.7 1.2 1 1 0 1 1 1 0 Retrotransposon gag protein Rho_Binding PF08912.6 ETO04875.1 - 0.45 10.8 18.1 1.5 9.1 12.6 1.8 1 1 0 1 1 1 0 Rho Binding DUF445 PF04286.7 ETO04875.1 - 0.47 9.9 6.4 0.49 9.8 4.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Lipoprotein_7 PF01540.11 ETO04875.1 - 0.49 9.4 9.2 0.53 9.2 6.4 1.0 1 0 0 1 1 1 0 Adhesin lipoprotein DUF3451 PF11933.3 ETO04875.1 - 0.62 9.8 8.4 0.67 9.7 5.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3451) Caps_synth_GfcC PF06251.6 ETO04875.1 - 0.71 8.9 3.5 0.77 8.8 2.5 1.1 1 0 0 1 1 1 0 Capsule biosynthesis GfcC AcylCoA_dehyd_C PF12186.3 ETO04875.1 - 0.73 9.7 5.8 0.93 9.3 4.0 1.3 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase C terminal NapB PF03892.9 ETO04875.1 - 0.74 9.5 3.8 0.75 9.4 2.6 1.1 1 0 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) ApoL PF05461.6 ETO04875.1 - 0.76 8.9 4.5 0.79 8.9 3.1 1.1 1 0 0 1 1 1 0 Apolipoprotein L GrpE PF01025.14 ETO04875.1 - 0.87 9.1 13.4 0.97 8.9 9.3 1.1 1 0 0 1 1 1 0 GrpE PilO PF04350.8 ETO04875.1 - 0.91 9.4 9.0 0.57 10.0 5.2 1.5 1 1 1 2 2 2 0 Pilus assembly protein, PilO Phage_GPO PF05929.6 ETO04875.1 - 0.96 8.6 8.5 1 8.5 5.9 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase CENP-H PF05837.7 ETO04875.1 - 0.98 9.6 13.0 1.1 9.5 9.0 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DIT1_PvcA PF05141.7 ETO04875.1 - 1.1 8.5 4.6 1.1 8.4 3.2 1.0 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein 4HB_MCP_1 PF12729.2 ETO04875.1 - 1.1 8.5 9.8 1.4 8.2 6.8 1.0 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction DUF883 PF05957.8 ETO04875.1 - 1.1 9.6 4.8 1.8 9.0 3.3 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) CENP-Q PF13094.1 ETO04875.1 - 1.2 9.1 13.7 1.4 8.9 9.5 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Exonuc_VII_L PF02601.10 ETO04875.1 - 1.3 8.0 8.3 1.3 8.1 5.8 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit pRN1_helical PF13010.1 ETO04875.1 - 1.4 8.5 9.8 1.5 8.4 6.8 1.0 1 0 0 1 1 1 0 Primase helical domain GBP_C PF02841.9 ETO04875.1 - 1.5 7.9 16.9 1.6 7.8 11.7 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Spc24 PF08286.6 ETO04875.1 - 1.7 8.3 11.6 2.1 8.0 8.0 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 YPEB PF14620.1 ETO04875.1 - 1.9 7.4 9.0 1.9 7.4 6.2 1.0 1 0 0 1 1 1 0 YpeB sporulation CmcH_NodU PF02543.10 ETO04875.1 - 1.9 7.5 5.1 2 7.4 3.6 1.0 1 0 0 1 1 1 0 Carbamoyltransferase DUF607 PF04678.8 ETO04875.1 - 2 8.3 8.4 3.2 7.6 5.8 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF607 DUF3498 PF12004.3 ETO04875.1 - 2 7.4 12.9 2.3 7.2 8.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) P4Ha_N PF08336.6 ETO04875.1 - 2.3 8.0 9.0 1.4 8.7 4.9 1.6 1 1 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region UPF0242 PF06785.6 ETO04875.1 - 2.5 6.7 10.5 2.5 6.6 7.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Cut12 PF11500.3 ETO04875.1 - 2.7 7.6 13.5 2.9 7.5 9.3 1.0 1 0 0 1 1 1 0 Spindle pole body formation-associated protein DUF2203 PF09969.4 ETO04875.1 - 2.7 8.2 7.1 2.8 8.2 4.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF1980 PF09323.5 ETO04875.1 - 2.8 7.6 7.8 3.1 7.5 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Cauli_AT PF03233.8 ETO04875.1 - 2.9 7.5 10.0 3.1 7.4 6.9 1.0 1 0 0 1 1 1 0 Aphid transmission protein DUF3450 PF11932.3 ETO04875.1 - 3 7.0 10.2 3.1 6.9 7.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4337 PF14235.1 ETO04875.1 - 3 7.6 10.1 3.1 7.6 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) ATP-synt_B PF00430.13 ETO04875.1 - 3.4 7.4 13.1 5 6.9 9.1 1.4 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) Phage_GP20 PF06810.6 ETO04875.1 - 3.7 6.9 17.7 8.4 5.8 12.2 1.6 1 1 0 1 1 1 0 Phage minor structural protein GP20 PspB PF06667.7 ETO04875.1 - 3.7 7.5 6.6 3.9 7.4 3.8 1.7 1 1 1 2 2 2 0 Phage shock protein B DUF3987 PF13148.1 ETO04875.1 - 4 5.8 9.9 4.4 5.7 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_13 PF13166.1 ETO04875.1 - 4.5 5.6 13.1 4.8 5.5 9.1 1.0 1 0 0 1 1 1 0 AAA domain DUF972 PF06156.8 ETO04875.1 - 4.6 7.6 11.4 5.3 7.4 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) APG6 PF04111.7 ETO04875.1 - 4.7 6.1 14.6 5 6.0 10.1 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 FYVE_2 PF02318.11 ETO04875.1 - 4.8 7.1 9.6 5.3 6.9 6.7 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger IncA PF04156.9 ETO04875.1 - 4.8 6.7 13.4 6.2 6.3 9.3 1.2 1 0 0 1 1 1 0 IncA protein DUF3198 PF11433.3 ETO04875.1 - 5.3 7.0 7.9 0.77 9.6 2.8 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF3198) YqfD PF06898.6 ETO04875.1 - 5.3 5.6 11.6 5.2 5.6 8.0 1.0 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD VIT1 PF01988.14 ETO04875.1 - 5.5 6.4 8.7 5.5 6.4 6.0 1.0 1 0 0 1 1 1 0 VIT family DUF342 PF03961.8 ETO04875.1 - 5.5 5.2 11.9 5.5 5.2 8.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Mgr1 PF08602.5 ETO04875.1 - 5.7 5.8 7.5 5.8 5.8 5.2 1.0 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit ACCA PF03255.9 ETO04875.1 - 6.2 6.3 7.7 7 6.1 5.4 1.2 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit TMPIT PF07851.8 ETO04875.1 - 6.4 5.7 9.7 6.3 5.7 6.7 1.0 1 0 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.14 ETO04875.1 - 6.9 4.3 9.9 6.9 4.3 6.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DASH_Dad2 PF08654.5 ETO04875.1 - 7.5 6.6 9.6 7.3 6.6 6.0 1.4 1 1 0 1 1 1 0 DASH complex subunit Dad2 Orbi_VP5 PF00901.12 ETO04875.1 - 7.7 4.5 11.5 8.5 4.4 7.9 1.0 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 LMBR1 PF04791.11 ETO04875.1 - 7.8 4.9 6.1 7.6 4.9 4.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein HSP70 PF00012.15 ETO04875.1 - 8.8 4.0 11.1 8.8 4.0 7.7 1.0 1 0 0 1 1 1 0 Hsp70 protein FemAB PF02388.11 ETO04875.1 - 9.3 4.8 13.1 10 4.7 9.1 1.0 1 0 0 1 1 1 0 FemAB family Ax_dynein_light PF10211.4 ETO04875.1 - 9.7 5.9 16.1 11 5.7 11.2 1.0 1 0 0 1 1 1 0 Axonemal dynein light chain FliJ PF02050.11 ETO04876.1 - 0.0055 16.7 2.0 0.01 15.8 1.4 1.4 1 0 0 1 1 1 1 Flagellar FliJ protein FAM117 PF15388.1 ETO04876.1 - 0.022 13.9 0.9 0.035 13.3 0.6 1.3 1 0 0 1 1 1 0 Protein Family FAM117 LZ_Tnp_IS66 PF13007.2 ETO04876.1 - 0.041 14.5 1.5 0.85 10.3 0.0 2.3 1 1 1 2 2 2 0 Transposase C of IS166 homeodomain AAA_24 PF13479.1 ETO04877.1 - 0.00014 21.5 0.6 0.00014 21.5 0.4 1.9 2 1 0 2 2 2 1 AAA domain DUF2052 PF09747.4 ETO04877.1 - 2.3 8.1 8.6 0.87 9.4 3.1 1.9 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Salp15 PF12115.3 ETO04877.1 - 5.2 7.3 7.3 2.7 8.2 0.1 2.5 2 1 0 2 2 2 0 Salivary protein of 15kDa inhibits CD4+ T cell activation Cass2 PF14526.1 ETO04878.1 - 0.072 13.0 0.3 0.12 12.3 0.2 1.3 1 0 0 1 1 1 0 Integron-associated effector binding protein WHIM1 PF15612.1 ETO04880.1 - 0.041 13.8 0.9 0.12 12.3 0.2 2.0 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 1 DNA_ligase_IV PF11411.3 ETO04880.1 - 0.2 11.4 2.1 0.51 10.1 1.5 1.7 1 0 0 1 1 1 0 DNA ligase IV Uso1_p115_head PF04869.9 ETO04882.1 - 0.088 11.5 0.2 0.39 9.4 0.0 1.8 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, head region Helicase_C PF00271.26 ETO04884.1 - 1.4e-15 56.8 0.1 6.1e-14 51.6 0.0 2.6 2 1 0 2 2 2 2 Helicase conserved C-terminal domain Rop PF01815.11 ETO04885.1 - 0.0062 15.9 0.1 0.014 14.8 0.1 1.7 1 0 0 1 1 1 1 Rop protein SNF5 PF04855.7 ETO04885.1 - 0.035 13.5 0.3 0.041 13.3 0.2 1.2 1 0 0 1 1 1 0 SNF5 / SMARCB1 / INI1 WD40 PF00400.27 ETO04887.1 - 3e-05 23.7 4.9 7.5e-05 22.4 0.7 2.4 2 1 0 2 2 2 1 WD domain, G-beta repeat DUF2578 PF10843.3 ETO04887.1 - 0.089 12.4 0.1 0.11 12.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2578) Kelch_4 PF13418.1 ETO04889.1 - 5.9e-06 25.9 0.0 0.0047 16.6 0.0 2.1 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO04889.1 - 5.4e-05 23.1 0.2 0.008 16.3 0.0 2.1 1 1 1 2 2 2 2 Kelch motif Kelch_1 PF01344.20 ETO04889.1 - 0.0014 18.1 0.1 0.052 13.1 0.0 2.2 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO04889.1 - 0.095 12.9 0.0 0.43 10.8 0.0 1.9 2 0 0 2 2 2 0 Galactose oxidase, central domain WD40 PF00400.27 ETO04890.1 - 1.6e-09 37.2 3.0 3.4e-09 36.2 2.1 1.6 1 0 0 1 1 1 1 WD domain, G-beta repeat TRAM_LAG1_CLN8 PF03798.11 ETO04890.1 - 0.22 11.0 5.7 0.29 10.6 4.0 1.1 1 0 0 1 1 1 0 TLC domain DUF1874 PF08960.5 ETO04893.1 - 0.013 15.2 0.8 0.026 14.2 0.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1874) WD40 PF00400.27 ETO04894.1 - 3.4e-16 58.4 4.9 1.4e-08 34.2 0.2 3.9 3 1 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO04894.1 - 0.0073 14.4 0.3 0.12 10.4 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO04894.1 - 0.0077 15.9 0.9 0.041 13.6 0.4 2.0 1 1 1 2 2 2 1 Ciliary BBSome complex subunit 2, middle region NAC PF01849.13 ETO04895.1 - 2.1e-13 49.5 2.1 3.2e-10 39.3 0.1 2.7 2 0 0 2 2 2 2 NAC domain FAP PF07174.6 ETO04895.1 - 4.3e-05 22.9 1.0 5.9e-05 22.5 0.7 1.1 1 0 0 1 1 1 1 Fibronectin-attachment protein (FAP) DUF2360 PF10152.4 ETO04895.1 - 0.034 14.4 0.7 0.069 13.4 0.5 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF1510 PF07423.6 ETO04895.1 - 0.048 13.0 3.6 0.091 12.1 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Menin PF05053.8 ETO04895.1 - 0.61 8.1 4.0 0.66 8.0 1.5 1.8 2 0 0 2 2 2 0 Menin Mucin PF01456.12 ETO04895.1 - 2.1 8.1 17.1 4.8 6.9 11.9 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein YolD PF08863.5 ETO04897.1 - 0.011 15.5 0.4 0.024 14.4 0.3 1.7 1 0 0 1 1 1 0 YolD-like protein Spidroin_MaSp PF11260.3 ETO04898.1 - 0.038 14.0 0.0 0.098 12.7 0.0 1.7 2 0 0 2 2 2 0 Major ampullate spidroin 1 and 2 DUF2857 PF11198.3 ETO04898.1 - 0.042 13.3 0.2 0.066 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) GILT PF03227.11 ETO04899.1 - 0.021 14.6 0.7 0.03 14.1 0.1 1.6 1 1 0 1 1 1 0 Gamma interferon inducible lysosomal thiol reductase (GILT) PMSI1 PF15322.1 ETO04899.1 - 0.49 9.4 2.5 0.5 9.4 1.8 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative RNA_pol_Rbc25 PF08292.7 ETO04899.1 - 0.95 9.6 4.0 1.4 9.1 2.8 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 DUF4446 PF14584.1 ETO04899.1 - 2.3 8.0 9.7 3.5 7.4 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Peptidase_S49_N PF08496.5 ETO04899.1 - 4.7 6.9 10.3 6.4 6.5 7.2 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal WD40 PF00400.27 ETO04900.1 - 2.2e-22 78.0 3.8 0.00061 19.5 0.1 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO04900.1 - 0.00026 19.2 1.0 0.2 9.7 0.0 3.0 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Peptidase_C14 PF00656.17 ETO04902.1 - 7.8e-07 29.0 0.4 1.3e-06 28.3 0.2 1.3 1 0 0 1 1 1 1 Caspase domain F-actin_cap_A PF01267.12 ETO04904.1 - 0.024 13.6 6.5 0.029 13.4 4.5 1.2 1 0 0 1 1 1 0 F-actin capping protein alpha subunit BHD_2 PF10404.4 ETO04904.1 - 0.63 10.3 3.1 0.71 10.2 1.0 1.9 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 2 PEPcase_2 PF14010.1 ETO04904.1 - 0.79 7.9 5.9 0.98 7.6 4.1 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase SseC PF04888.7 ETO04904.1 - 9.6 5.4 8.2 13 4.9 5.7 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Tubulin PF00091.20 ETO04910.1 - 1.5e-22 80.4 0.0 2e-22 80.1 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.1 ETO04910.1 - 0.11 11.3 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Tubulin like CKS PF01111.14 ETO04910.1 - 0.15 11.9 0.6 0.56 10.0 0.1 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase regulatory subunit DEAD PF00270.24 ETO04911.1 - 3.6e-18 65.6 0.0 4.3e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 ETO04911.1 - 1.3e-05 25.1 0.0 1.8e-05 24.6 0.0 1.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 ETO04911.1 - 0.016 14.4 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 SecA DEAD-like domain Flavi_DEAD PF07652.9 ETO04911.1 - 0.14 11.8 0.0 2.3 7.9 0.0 2.1 2 0 0 2 2 2 0 Flavivirus DEAD domain Tubulin_C PF03953.12 ETO04913.1 - 2.4e-34 118.1 0.0 3.4e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain DUF4339 PF14237.1 ETO04916.1 - 2.7e-05 23.6 2.7 2.7e-05 23.6 0.3 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4339) Kelch_1 PF01344.20 ETO04916.1 - 0.0059 16.1 1.7 0.01 15.3 0.3 2.0 2 0 0 2 2 2 1 Kelch motif SOG2 PF10428.4 ETO04916.1 - 3.2 6.3 9.7 2.5 6.6 6.0 1.3 2 0 0 2 2 2 0 RAM signalling pathway protein DUF2451 PF10474.4 ETO04918.1 - 1.1e-31 110.3 0.5 1.6e-31 109.8 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) ELYS PF13934.1 ETO04918.1 - 0.018 14.7 0.4 0.026 14.2 0.3 1.2 1 0 0 1 1 1 0 Nuclear pore complex assembly zf-TRAF PF02176.13 ETO04919.1 - 1.6e-07 31.6 2.7 1.6e-07 31.6 1.9 2.2 3 0 0 3 3 3 1 TRAF-type zinc finger DUF972 PF06156.8 ETO04919.1 - 0.0084 16.4 1.2 0.02 15.2 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF972) zf-C3HC4_2 PF13923.1 ETO04919.1 - 4.4 7.4 10.3 2.1 8.4 0.9 3.9 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Cmyb_C PF09316.5 ETO04920.1 - 0.0099 15.5 0.3 0.012 15.3 0.2 1.1 1 0 0 1 1 1 1 C-myb, C-terminal DUF4337 PF14235.1 ETO04920.1 - 0.43 10.3 2.0 0.59 9.9 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Pkinase PF00069.20 ETO04921.1 - 1.3e-10 40.8 0.0 2.9e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO04921.1 - 5e-06 25.7 0.0 1.6e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase CAP_GLY PF01302.20 ETO04922.1 - 2.4e-06 27.1 0.3 0.03 14.0 0.0 2.2 2 0 0 2 2 2 2 CAP-Gly domain TIM21 PF08294.6 ETO04923.1 - 0.0041 16.7 0.0 0.0054 16.3 0.0 1.2 1 0 0 1 1 1 1 TIM21 WGR PF05406.10 ETO04923.1 - 0.075 13.0 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 WGR domain Peptidase_A21 PF03566.8 ETO04923.1 - 0.085 10.9 0.4 0.086 10.9 0.3 1.0 1 0 0 1 1 1 0 Peptidase family A21 RPAP1_N PF08621.5 ETO04924.1 - 7.5e-10 38.2 1.0 2.6e-09 36.5 0.3 2.2 2 0 0 2 2 2 1 RPAP1-like, N-terminal RPAP1_C PF08620.5 ETO04924.1 - 4.6e-08 32.8 0.5 4.6e-08 32.8 0.4 3.3 3 1 0 3 3 3 1 RPAP1-like, C-terminal BetaGal_dom3 PF13363.1 ETO04924.1 - 0.041 13.2 0.1 0.28 10.6 0.0 2.4 2 0 0 2 2 2 0 Beta-galactosidase, domain 3 Prion PF00377.13 ETO04924.1 - 0.12 12.0 0.2 0.12 12.0 0.1 2.7 3 0 0 3 3 3 0 Prion/Doppel alpha-helical domain DUF1685 PF07939.6 ETO04924.1 - 0.19 11.4 3.4 2 8.1 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1685) DUF1117 PF06547.7 ETO04924.1 - 1.4 9.0 3.9 5.7 7.0 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) WD40 PF00400.27 ETO04925.1 - 5e-19 67.4 1.6 1.3e-12 47.0 0.0 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO04925.1 - 0.00022 19.5 0.2 0.034 12.2 0.0 2.0 1 1 0 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO04925.1 - 0.0046 15.7 0.4 0.76 8.4 0.1 2.0 1 1 1 2 2 2 2 Nup133 N terminal like DUF3601 PF12208.3 ETO04925.1 - 0.007 16.2 0.0 0.0089 15.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3601) DUF1675 PF07897.6 ETO04928.1 - 0.12 12.2 23.6 0.15 11.9 16.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) MIP-T3 PF10243.4 ETO04928.1 - 1.9 6.8 37.1 2.2 6.6 25.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Peptidase_S64 PF08192.6 ETO04928.1 - 2.9 6.1 20.1 3.4 5.8 13.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF1387 PF07139.6 ETO04928.1 - 2.9 7.3 25.1 3.6 7.1 17.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) TFIIF_alpha PF05793.7 ETO04928.1 - 7.1 4.8 34.4 8.7 4.5 23.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ABC2_membrane PF01061.19 ETO04929.1 - 8.2e-15 54.5 16.6 8.2e-15 54.5 11.5 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 ETO04929.1 - 4.8e-05 22.5 15.0 4.8e-05 22.5 10.4 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein v110 PF01639.12 ETO04930.1 - 0.019 14.5 0.6 0.025 14.1 0.1 1.5 2 0 0 2 2 2 0 Viral family 110 Ninjurin PF04923.7 ETO04931.1 - 0.091 12.4 2.2 0.16 11.7 1.5 1.4 1 0 0 1 1 1 0 Ninjurin Sugar_tr PF00083.19 ETO04933.1 - 5.1e-53 180.2 4.9 8.4e-53 179.5 3.4 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETO04933.1 - 2.1e-15 56.3 38.8 1.6e-10 40.2 10.7 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2178 PF09946.4 ETO04933.1 - 0.035 13.8 0.6 0.035 13.8 0.4 2.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2178) SHP PF03579.8 ETO04933.1 - 0.093 12.0 4.1 5.4 6.4 1.0 2.6 2 0 0 2 2 2 0 Small hydrophobic protein DUF1624 PF07786.7 ETO04933.1 - 0.29 10.4 9.1 0.52 9.6 6.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1624) Fmp27_WPPW PF10359.4 ETO04935.1 - 0.0041 15.5 6.9 0.0075 14.7 4.8 1.4 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF3530 PF12048.3 ETO04935.1 - 0.011 14.7 0.2 0.017 14.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) CENP-B_dimeris PF09026.5 ETO04935.1 - 0.058 13.6 4.7 3.7 7.8 0.9 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PEX11 PF05648.9 ETO04935.1 - 0.069 12.4 3.2 0.14 11.3 2.3 1.5 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) DDHD PF02862.12 ETO04935.1 - 0.11 12.3 4.7 0.19 11.4 3.3 1.3 1 0 0 1 1 1 0 DDHD domain Peptidase_S30 PF01577.11 ETO04935.1 - 0.2 10.9 9.8 0.32 10.3 6.8 1.2 1 0 0 1 1 1 0 Potyvirus P1 protease Hom_end_hint PF05203.11 ETO04935.1 - 0.29 10.8 4.9 0.12 12.0 1.7 1.5 2 0 0 2 2 2 0 Hom_end-associated Hint UvrD-helicase PF00580.16 ETO04935.1 - 1.1 8.5 15.9 1.6 7.9 11.0 1.5 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain NPFF PF15085.1 ETO04935.1 - 1.4 9.2 5.4 3.1 8.1 1.7 2.4 3 0 0 3 3 3 0 Neuropeptide FF Med19 PF10278.4 ETO04935.1 - 1.7 8.2 15.0 3 7.4 10.4 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 PBP1_TM PF14812.1 ETO04935.1 - 6.1 7.2 15.2 12 6.2 6.1 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA_11 PF13086.1 ETO04935.1 - 8.7 5.8 10.0 17 4.9 6.9 1.4 1 0 0 1 1 1 0 AAA domain FAM176 PF14851.1 ETO04935.1 - 9.8 5.8 9.6 6.6 6.4 2.7 2.5 3 0 0 3 3 3 0 FAM176 family RVT_1 PF00078.22 ETO04938.1 - 1e-09 38.0 0.1 1.1e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_gp53 PF11246.3 ETO04938.1 - 0.035 13.5 0.0 0.07 12.5 0.0 1.5 1 1 0 1 1 1 0 Base plate wedge protein 53 Herpes_TK_C PF08465.5 ETO04938.1 - 0.11 12.0 0.3 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 Thymidine kinase from Herpesvirus C-terminal fn3 PF00041.16 ETO04940.1 - 0.0067 16.5 0.0 3.8 7.7 0.0 2.7 2 0 0 2 2 2 2 Fibronectin type III domain SAM_1 PF00536.25 ETO04941.1 - 0.047 13.8 0.0 0.077 13.1 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) WD40 PF00400.27 ETO04942.1 - 6.2e-141 453.8 44.2 1.3e-11 43.8 0.1 15.1 15 0 0 15 15 15 14 WD domain, G-beta repeat Nup160 PF11715.3 ETO04942.1 - 5.4e-10 38.0 23.7 0.27 9.3 0.1 9.8 2 2 7 9 9 9 5 Nucleoporin Nup120/160 PD40 PF07676.7 ETO04942.1 - 1.4e-07 31.0 12.7 2.6 7.8 0.0 8.6 9 0 0 9 9 9 2 WD40-like Beta Propeller Repeat DUF3601 PF12208.3 ETO04942.1 - 3.8e-07 29.9 1.4 6.7 6.7 0.0 7.0 5 2 2 7 7 7 1 Domain of unknown function (DUF3601) Cytochrom_D1 PF02239.11 ETO04942.1 - 2e-05 23.0 6.5 0.28 9.4 0.0 4.9 3 1 0 5 5 5 2 Cytochrome D1 heme domain Mid2 PF04478.7 ETO04942.1 - 9.7e-05 21.8 10.9 0.7 9.2 0.0 6.9 5 1 5 10 10 10 1 Mid2 like cell wall stress sensor DUF1938 PF09153.5 ETO04942.1 - 0.00013 21.6 1.4 3.1 7.6 0.0 4.7 3 2 1 4 4 4 1 Domain of unknown function (DUF1938) Me-amine-dh_H PF06433.6 ETO04942.1 - 0.00072 18.2 0.1 0.26 9.8 0.0 3.8 4 0 0 4 4 4 1 Methylamine dehydrogenase heavy chain (MADH) IKI3 PF04762.7 ETO04942.1 - 0.00078 17.3 2.9 0.68 7.6 0.1 4.1 3 1 1 4 4 4 2 IKI3 family Str_synth PF03088.11 ETO04942.1 - 0.00093 19.1 1.4 2.9 7.9 0.0 5.6 5 3 1 6 6 5 1 Strictosidine synthase Resistin PF06954.6 ETO04942.1 - 0.0024 18.1 0.1 12 6.2 0.0 4.8 2 1 1 4 4 4 0 Resistin Ricin_B_lectin PF00652.17 ETO04942.1 - 0.0093 15.9 15.3 1.5 8.8 0.1 6.6 2 2 6 8 8 8 1 Ricin-type beta-trefoil lectin domain DUF2441 PF10386.4 ETO04942.1 - 0.042 13.8 0.0 24 4.9 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF2441) USP7_C2 PF14533.1 ETO04942.1 - 0.071 12.5 3.8 8.7 5.7 0.1 5.3 5 2 1 6 6 6 0 Ubiquitin-specific protease C-terminal Peptidase_C69 PF03577.10 ETO04942.1 - 0.41 9.4 5.0 8.9 5.0 0.0 4.5 5 1 1 6 6 6 0 Peptidase family C69 PH PF00169.24 ETO04943.1 - 7.2 6.8 6.7 4.6 7.4 1.8 2.7 1 1 1 2 2 2 0 PH domain zf-RanBP PF00641.13 ETO04944.1 - 0.0061 15.6 2.9 0.0061 15.6 2.0 1.7 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others TPR_12 PF13424.1 ETO04946.1 - 2e-23 82.1 4.1 2e-09 37.2 0.0 4.6 1 1 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO04946.1 - 2.2e-15 55.1 5.5 1.1e-06 27.9 0.0 5.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO04946.1 - 1.2e-13 49.9 16.1 7.3e-08 31.6 0.7 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO04946.1 - 1.5e-10 40.5 10.6 5.5e-05 22.7 0.6 3.8 3 1 0 3 3 3 3 TPR repeat TPR_10 PF13374.1 ETO04946.1 - 4.2e-10 39.2 0.0 0.00065 19.5 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO04946.1 - 4.4e-10 38.6 9.7 6e-05 22.6 0.2 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO04946.1 - 2.1e-09 36.4 25.7 1.1e-05 24.8 1.7 5.1 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO04946.1 - 1.3e-05 24.9 4.8 0.016 15.3 0.0 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO04946.1 - 0.0026 16.9 0.1 1.3 8.2 0.0 3.2 3 0 0 3 3 3 1 SHNi-TPR TPR_16 PF13432.1 ETO04946.1 - 0.004 17.8 0.0 9.1 7.0 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETO04946.1 - 0.0085 16.6 0.0 7.9 7.4 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 ETO04946.1 - 0.05 13.4 4.8 1 9.3 0.3 2.6 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 ETO04946.1 - 0.1 12.4 3.0 8.6 6.2 0.2 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat PG_binding_4 PF12229.3 ETO04946.1 - 0.17 12.1 4.7 0.07 13.3 0.6 2.0 1 1 2 3 3 3 0 Putative peptidoglycan binding domain Aldo_ket_red PF00248.16 ETO04946.1 - 0.18 10.5 3.7 0.59 8.9 2.5 1.8 1 1 0 1 1 1 0 Aldo/keto reductase family OEP PF02321.13 ETO04946.1 - 0.22 11.0 1.0 1.9 8.0 0.1 2.1 2 0 0 2 2 2 0 Outer membrane efflux protein Sel1 PF08238.7 ETO04946.1 - 0.32 11.7 4.5 9.1 7.0 0.1 3.3 3 0 0 3 3 3 0 Sel1 repeat DUF3439 PF11921.3 ETO04948.1 - 5.4e-05 22.9 5.0 5.4e-05 22.9 3.5 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) SSP160 PF06933.6 ETO04948.1 - 0.0008 17.5 4.8 0.00096 17.2 3.3 1.2 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 SRP-alpha_N PF04086.8 ETO04948.1 - 0.26 10.6 22.4 0.34 10.2 15.5 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DNA_pol_viral_N PF00242.12 ETO04948.1 - 0.73 8.7 13.5 0.94 8.4 9.4 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Utp14 PF04615.8 ETO04948.1 - 0.77 7.8 28.8 0.94 7.5 19.9 1.0 1 0 0 1 1 1 0 Utp14 protein Mucin PF01456.12 ETO04948.1 - 3.3 7.4 23.3 0.3 10.8 11.9 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein GTP_EFTU PF00009.22 ETO04950.1 - 0.00081 18.8 0.2 0.003 17.0 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain L27_2 PF09045.5 ETO04950.1 - 0.15 11.6 3.1 0.93 9.0 0.8 2.3 2 0 0 2 2 2 0 L27_2 Inositol_P PF00459.20 ETO04951.1 - 6.4e-26 91.2 0.1 9.9e-25 87.3 0.0 2.5 1 1 1 2 2 2 1 Inositol monophosphatase family Ycf1 PF05758.7 ETO04951.1 - 0.004 14.9 5.0 0.0051 14.6 3.5 1.1 1 0 0 1 1 1 1 Ycf1 CDC45 PF02724.9 ETO04951.1 - 0.017 13.2 3.6 0.021 12.8 2.5 1.2 1 0 0 1 1 1 0 CDC45-like protein TMEM51 PF15345.1 ETO04951.1 - 0.084 12.5 9.4 0.14 11.8 6.5 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Afi1 PF07792.7 ETO04951.1 - 0.1 12.6 5.0 0.19 11.7 3.5 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2252 PF10009.4 ETO04951.1 - 0.1 11.4 3.4 0.15 10.9 2.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Hid1 PF12722.2 ETO04951.1 - 0.2 9.3 8.7 0.26 8.9 6.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4557 PF15101.1 ETO04951.1 - 0.23 11.2 7.9 0.41 10.4 5.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF1510 PF07423.6 ETO04951.1 - 0.49 9.7 12.8 1 8.6 8.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Barttin PF15462.1 ETO04951.1 - 0.5 9.9 7.4 0.88 9.1 5.1 1.3 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Peptidase_S64 PF08192.6 ETO04951.1 - 0.65 8.2 7.1 0.86 7.8 4.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 Peptidase_S30 PF01577.11 ETO04951.1 - 0.71 9.2 11.6 1.2 8.4 8.1 1.2 1 0 0 1 1 1 0 Potyvirus P1 protease Nucleoside_tran PF01733.13 ETO04951.1 - 0.72 8.9 2.4 0.65 9.1 0.7 1.5 2 0 0 2 2 2 0 Nucleoside transporter FAM176 PF14851.1 ETO04951.1 - 1.6 8.4 6.5 47 3.6 4.6 2.4 2 0 0 2 2 2 0 FAM176 family Ndc1_Nup PF09531.5 ETO04951.1 - 1.8 6.9 5.6 2.4 6.4 3.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pex16 PF08610.5 ETO04951.1 - 3.2 6.6 8.8 4.7 6.1 6.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF3682 PF12446.3 ETO04951.1 - 3.2 8.0 18.3 7.2 6.9 12.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Folate_carrier PF01770.13 ETO04951.1 - 4.2 5.7 5.2 7.5 4.9 3.6 1.3 1 0 0 1 1 1 0 Reduced folate carrier FAM60A PF15396.1 ETO04951.1 - 4.3 7.0 11.4 13 5.5 7.7 1.8 2 0 0 2 2 2 0 Protein Family FAM60A DUF2215 PF10225.4 ETO04951.1 - 6.6 6.0 9.1 15 4.9 6.3 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) EF-hand_7 PF13499.1 ETO04952.1 - 3.5e-07 30.2 0.2 8e-07 29.1 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO04952.1 - 1.4e-06 27.1 0.0 0.0062 15.7 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 ETO04952.1 - 3.3e-05 23.4 0.7 0.04 13.5 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO04952.1 - 0.00058 19.5 0.1 0.82 9.7 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 ETO04952.1 - 0.022 14.0 0.1 3.1 7.3 0.0 2.5 2 0 0 2 2 2 0 EF hand SPARC_Ca_bdg PF10591.4 ETO04952.1 - 0.2 11.7 2.1 0.76 9.8 1.4 2.1 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region HTH_Tnp_Tc5 PF03221.11 ETO04954.1 - 0.039 13.7 0.0 0.089 12.6 0.0 1.7 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain Utp13 PF08625.6 ETO04954.1 - 0.074 12.7 1.6 1.6 8.3 0.0 2.3 1 1 1 2 2 2 0 Utp13 specific WD40 associated domain Vac14_Fab1_bd PF12755.2 ETO04954.1 - 0.26 11.7 1.7 5.2 7.5 0.1 2.8 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Fib_alpha PF08702.5 ETO04955.1 - 0.025 14.7 3.3 0.025 14.7 2.3 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Laminin_I PF06008.9 ETO04955.1 - 0.029 13.6 2.9 0.035 13.4 1.7 1.4 1 1 0 1 1 1 0 Laminin Domain I GldM_N PF12081.3 ETO04955.1 - 0.046 13.2 7.1 0.051 13.1 4.9 1.0 1 0 0 1 1 1 0 GldM N-terminal domain RP-C_C PF11800.3 ETO04955.1 - 0.076 12.7 0.6 0.085 12.5 0.4 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Methyltransf_9 PF08003.6 ETO04955.1 - 0.09 11.4 1.1 0.092 11.4 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DUF2353 PF09789.4 ETO04955.1 - 0.096 11.9 4.8 0.12 11.6 3.3 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) GTP_EFTU PF00009.22 ETO04955.1 - 0.11 11.9 4.6 0.15 11.4 1.9 1.8 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Mur_ligase_M PF08245.7 ETO04955.1 - 0.11 12.5 1.2 0.12 12.3 0.8 1.0 1 0 0 1 1 1 0 Mur ligase middle domain Rota_NSP4 PF01452.11 ETO04955.1 - 0.12 11.6 5.7 0.14 11.4 4.0 1.1 1 0 0 1 1 1 0 Rotavirus non structural protein Prominin PF05478.6 ETO04955.1 - 0.13 9.8 5.0 0.14 9.6 3.5 1.0 1 0 0 1 1 1 0 Prominin CortBP2 PF09727.4 ETO04955.1 - 0.14 11.6 5.9 0.2 11.1 4.1 1.2 1 0 0 1 1 1 0 Cortactin-binding protein-2 Phage_Mu_Gam PF07352.7 ETO04955.1 - 0.15 11.5 6.4 0.049 13.1 2.0 1.8 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein FlaC_arch PF05377.6 ETO04955.1 - 0.2 11.5 7.1 0.089 12.6 1.5 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) YflT PF11181.3 ETO04955.1 - 0.2 11.8 2.1 0.39 10.8 1.4 1.6 1 1 0 1 1 1 0 Heat induced stress protein YflT DUF4298 PF14131.1 ETO04955.1 - 0.26 11.1 3.0 0.17 11.7 0.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4298) OEP PF02321.13 ETO04955.1 - 0.27 10.8 2.2 0.33 10.5 1.5 1.1 1 0 0 1 1 1 0 Outer membrane efflux protein Clusterin PF01093.12 ETO04955.1 - 0.32 9.7 4.9 0.52 9.0 3.4 1.3 1 1 0 1 1 1 0 Clusterin Laminin_II PF06009.7 ETO04955.1 - 0.33 10.6 2.7 0.68 9.6 1.9 1.6 1 1 0 1 1 1 0 Laminin Domain II IncA PF04156.9 ETO04955.1 - 0.47 10.0 3.2 0.65 9.5 2.2 1.2 1 0 0 1 1 1 0 IncA protein IL2 PF00715.12 ETO04955.1 - 0.7 9.6 4.1 3.3 7.4 0.1 2.1 1 1 1 2 2 2 0 Interleukin 2 DUF972 PF06156.8 ETO04955.1 - 1 9.7 5.7 2.6 8.4 3.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF342 PF03961.8 ETO04955.1 - 1.3 7.4 8.6 1.4 7.2 6.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DivIC PF04977.10 ETO04955.1 - 3 7.4 8.1 2.2 7.8 3.1 2.0 2 0 0 2 2 2 0 Septum formation initiator CCDC155 PF14662.1 ETO04955.1 - 4 6.9 8.3 2 8.0 1.3 1.9 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 DUF3439 PF11921.3 ETO04956.1 - 3.8 7.2 8.8 1.6 8.5 1.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) TraC_F_IV PF11130.3 ETO04958.1 - 0.045 13.1 0.2 0.08 12.3 0.1 1.4 1 0 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer Mit_ribos_Mrp51 PF11709.3 ETO04958.1 - 0.27 10.3 5.2 0.3 10.2 3.6 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit Hormone_1 PF00103.15 ETO04958.1 - 0.39 10.0 10.0 0.027 13.8 3.0 1.8 2 0 0 2 2 2 0 Somatotropin hormone family MADF_DNA_bdg PF10545.4 ETO04958.1 - 0.4 10.8 4.5 0.23 11.6 1.1 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Lzipper-MIP1 PF14389.1 ETO04958.1 - 1.4 9.0 12.6 0.41 10.7 5.5 2.5 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF1664 PF07889.7 ETO04958.1 - 3.4 7.4 13.7 4.5 7.0 0.7 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Kinesin-relat_1 PF12711.2 ETO04958.1 - 4.2 7.8 13.2 0.95 9.8 5.0 2.8 2 1 1 3 3 3 0 Kinesin motor ApoO PF09769.4 ETO04958.1 - 6.9 6.3 7.5 4.6 6.9 2.9 2.2 2 1 0 2 2 2 0 Apolipoprotein O Metallophos PF00149.23 ETO04959.1 - 7.8e-24 84.1 0.3 1.2e-23 83.5 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NTP_transferase PF00483.18 ETO04960.1 - 9.3e-45 152.8 0.0 1.3e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 ETO04960.1 - 2.1e-11 44.1 0.0 2.5e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 ETO04960.1 - 0.0072 15.8 0.0 0.013 15.0 0.0 1.4 2 0 0 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Hexapep PF00132.19 ETO04961.1 - 2.2e-12 45.8 5.5 3.6e-08 32.5 1.4 3.3 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 ETO04961.1 - 0.041 13.4 5.3 0.072 12.6 1.8 2.7 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase TPR_11 PF13414.1 ETO04962.1 - 3.4e-09 36.2 1.3 0.00014 21.4 0.1 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 ETO04962.1 - 2.7e-05 23.7 3.3 0.083 12.8 0.2 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO04962.1 - 8.3e-05 22.4 4.0 0.0001 22.1 0.4 2.8 2 2 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO04962.1 - 0.00024 20.6 6.7 0.024 14.4 0.1 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO04962.1 - 0.00076 18.9 6.9 0.0084 15.6 0.2 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_18 PF13512.1 ETO04962.1 - 0.01 15.8 0.2 0.051 13.6 0.0 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 ETO04962.1 - 0.025 14.7 0.1 1.8 8.9 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat SecY PF00344.15 ETO04962.1 - 0.027 13.4 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 SecY translocase Methyltransf_12 PF08242.7 ETO04962.1 - 0.066 13.6 0.3 0.21 12.0 0.1 2.0 2 0 0 2 2 2 0 Methyltransferase domain TPR_14 PF13428.1 ETO04962.1 - 0.11 13.1 0.0 2.2 9.1 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat Zip PF02535.17 ETO04962.1 - 4.6 6.1 7.7 9.3 5.1 4.5 2.0 1 1 1 2 2 2 0 ZIP Zinc transporter TPR_11 PF13414.1 ETO04963.1 - 1.1e-11 44.1 10.0 1.6e-05 24.4 0.0 3.4 3 0 0 3 3 3 3 TPR repeat TPR_2 PF07719.12 ETO04963.1 - 3.6e-09 35.8 8.7 0.061 13.2 0.0 5.5 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO04963.1 - 5.9e-09 35.0 2.3 0.021 14.5 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO04963.1 - 1.4e-08 34.2 5.0 4.5e-05 23.3 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO04963.1 - 3.1e-07 30.2 7.9 0.0064 16.4 0.0 3.6 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO04963.1 - 1.4e-06 28.7 0.7 0.039 14.6 0.2 3.5 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO04963.1 - 0.00089 18.7 11.2 0.28 10.8 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO04963.1 - 0.0036 17.6 1.1 0.19 12.0 0.4 3.3 2 2 1 3 3 3 1 Tetratricopeptide repeat Metallophos PF00149.23 ETO04964.1 - 8.1e-13 48.2 0.0 1.4e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2259 PF10016.4 ETO04964.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Predicted secreted protein (DUF2259) Kelch_5 PF13854.1 ETO04965.1 - 0.013 15.4 0.1 0.096 12.6 0.1 2.2 2 0 0 2 2 2 0 Kelch motif Kelch_6 PF13964.1 ETO04965.1 - 0.05 13.7 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Kelch motif Kelch_1 PF01344.20 ETO04965.1 - 0.2 11.2 1.3 0.41 10.2 0.1 2.2 2 0 0 2 2 2 0 Kelch motif zf-RanBP PF00641.13 ETO04966.1 - 5.2e-06 25.4 7.0 1.3e-05 24.1 4.9 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others HAD_2 PF13419.1 ETO04967.1 - 0.00033 20.9 0.0 0.17 12.0 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 ETO04967.1 - 0.017 15.0 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ETO04967.1 - 0.039 13.6 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 HAD-hyrolase-like Afi1 PF07792.7 ETO04969.1 - 0.022 14.7 1.3 0.032 14.2 0.9 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SPT16 PF08644.6 ETO04969.1 - 0.066 13.0 0.3 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) ADP_ribosyl_GH PF03747.9 ETO04969.1 - 0.068 12.9 0.0 0.19 11.4 0.0 1.7 2 0 0 2 2 2 0 ADP-ribosylglycohydrolase ABA_GPCR PF12430.3 ETO04969.1 - 0.087 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Abscisic acid G-protein coupled receptor PDR_CDR PF06422.7 ETO04969.1 - 0.15 11.7 1.3 12 5.6 0.5 2.5 2 0 0 2 2 2 0 CDR ABC transporter PcfJ PF14284.1 ETO04969.1 - 0.22 10.9 4.0 0.33 10.4 2.8 1.2 1 0 0 1 1 1 0 PcfJ-like protein WD40 PF00400.27 ETO04970.1 - 9e-120 386.7 30.6 5.7e-10 38.6 0.0 16.5 16 0 0 16 16 16 15 WD domain, G-beta repeat NACHT PF05729.7 ETO04970.1 - 2.5e-08 33.7 0.0 5e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.7 ETO04970.1 - 1.5e-06 27.7 18.6 0.24 11.1 0.1 10.0 12 0 0 12 12 12 2 WD40-like Beta Propeller Repeat AAA_18 PF13238.1 ETO04970.1 - 6.5e-06 26.4 1.5 3.3e-05 24.1 0.1 3.0 2 0 0 2 2 2 1 AAA domain Pentapeptide PF00805.17 ETO04970.1 - 7.3e-06 25.0 0.8 1.5e-05 24.1 0.5 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) AAA_22 PF13401.1 ETO04970.1 - 5.5e-05 23.3 0.0 0.00017 21.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain Pentapeptide_4 PF13599.1 ETO04970.1 - 8.1e-05 22.3 0.1 0.0002 21.0 0.1 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) PQQ_2 PF13360.1 ETO04970.1 - 0.002 17.6 3.3 0.2 11.1 0.4 3.6 1 1 2 3 3 3 2 PQQ-like domain Pentapeptide_3 PF13576.1 ETO04970.1 - 0.004 17.0 0.1 0.015 15.1 0.1 2.0 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA_17 PF13207.1 ETO04970.1 - 0.0065 17.2 0.2 0.056 14.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain XPG_I_2 PF12813.2 ETO04970.1 - 0.014 14.9 1.0 0.024 14.1 0.2 1.7 2 0 0 2 2 2 0 XPG domain containing KaiC PF06745.8 ETO04970.1 - 0.017 14.2 4.8 1.1 8.2 0.0 3.6 3 1 0 3 3 3 0 KaiC vMSA PF00695.14 ETO04971.1 - 0.00069 18.9 1.0 0.0032 16.7 0.0 1.9 1 1 1 2 2 2 1 Major surface antigen from hepadnavirus Secretin_N_2 PF07655.8 ETO04971.1 - 0.63 10.4 15.5 1.6 9.1 10.7 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain Peptidase_C14 PF00656.17 ETO04975.1 - 0.017 14.8 0.2 0.022 14.4 0.1 1.2 1 0 0 1 1 1 0 Caspase domain WD40 PF00400.27 ETO04976.1 - 6.2e-46 152.6 6.5 4.4e-12 45.3 0.1 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO04976.1 - 2.5e-09 35.8 3.3 0.0027 15.8 0.0 3.6 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO04976.1 - 2.9e-08 32.4 0.2 0.0051 15.1 0.0 3.5 1 1 3 4 4 4 3 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO04976.1 - 4.7e-06 26.2 0.0 1e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 PQQ-like domain DPPIV_N PF00930.16 ETO04976.1 - 0.0013 17.4 0.1 1.2 7.6 0.0 3.3 1 1 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nucleoporin_N PF08801.6 ETO04976.1 - 0.0014 17.5 2.8 0.46 9.1 0.1 3.1 1 1 3 4 4 4 2 Nup133 N terminal like Asp_decarbox PF02261.11 ETO04976.1 - 0.01 15.3 0.0 7.3 6.2 0.0 3.6 3 2 1 4 4 4 0 Aspartate decarboxylase Proteasome_A_N PF10584.4 ETO04976.1 - 0.02 14.1 0.6 23 4.4 0.0 4.2 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature MRJP PF03022.11 ETO04976.1 - 0.056 12.6 0.2 0.88 8.7 0.0 2.5 1 1 2 3 3 3 0 Major royal jelly protein PDDEXK_1 PF12705.2 ETO04976.1 - 0.068 12.5 0.0 12 5.1 0.0 2.4 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily A_deamin PF02137.13 ETO04976.1 - 0.083 12.1 0.6 0.25 10.6 0.1 1.9 2 1 0 2 2 2 0 Adenosine-deaminase (editase) domain Hira PF07569.6 ETO04976.1 - 0.11 11.7 0.1 16 4.5 0.0 3.3 3 1 1 4 4 4 0 TUP1-like enhancer of split Resistin PF06954.6 ETO04976.1 - 0.14 12.4 1.0 8.9 6.6 0.0 2.9 2 2 0 2 2 2 0 Resistin Kelch_1 PF01344.20 ETO04977.1 - 6.5e-07 28.7 1.3 0.13 11.8 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO04977.1 - 1.7e-05 24.8 5.0 0.26 11.5 0.0 4.5 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO04977.1 - 3.4e-05 23.4 1.7 0.13 12.0 0.1 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO04977.1 - 0.00019 21.2 1.8 0.15 12.0 0.0 3.9 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO04977.1 - 0.025 14.3 0.4 15 5.4 0.0 3.9 5 0 0 5 5 5 0 Galactose oxidase, central domain Cad PF03596.8 ETO04978.1 - 0.07 12.8 1.8 0.68 9.5 1.2 2.0 1 1 0 1 1 1 0 Cadmium resistance transporter MMR1 PF08505.5 ETO04979.1 - 0.21 11.5 3.5 0.26 11.2 2.4 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Pkinase PF00069.20 ETO04979.1 - 0.4 9.7 5.8 1.3 8.0 2.0 2.5 2 1 1 3 3 3 0 Protein kinase domain Acetyltransf_1 PF00583.19 ETO04980.1 - 4.1e-13 49.1 0.0 5.9e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETO04980.1 - 1.4e-12 47.5 0.1 2.2e-12 46.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 ETO04980.1 - 1.1e-07 31.9 0.2 1.3e-07 31.6 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETO04980.1 - 3.7e-05 23.5 0.0 5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 ETO04980.1 - 7.2e-05 22.9 0.0 8.7e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETO04980.1 - 0.00055 19.6 0.0 0.0015 18.2 0.0 1.6 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.1 ETO04980.1 - 0.002 18.2 0.0 0.0025 17.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 ETO04980.1 - 0.0078 16.0 0.1 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Borrelia_lipo_2 PF06238.6 ETO04980.1 - 0.026 14.5 1.3 0.86 9.6 0.0 2.2 2 0 0 2 2 2 0 Borrelia burgdorferi BBR25 lipoprotein TetR_C_5 PF08360.6 ETO04980.1 - 0.037 14.0 1.0 4.7 7.1 0.2 2.1 2 0 0 2 2 2 0 QacR-like protein, C-terminal region Acetyltransf_8 PF13523.1 ETO04980.1 - 0.049 13.5 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MA3 PF02847.12 ETO04980.1 - 0.11 12.1 0.1 0.26 11.0 0.0 1.6 2 0 0 2 2 2 0 MA3 domain zf-TRAF PF02176.13 ETO04982.1 - 5.4e-05 23.4 2.9 9.1e-05 22.7 0.1 2.8 2 1 1 3 3 3 1 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 ETO04982.1 - 0.0048 16.9 3.4 0.028 14.4 0.9 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO04982.1 - 0.0058 16.4 1.6 0.0058 16.4 1.1 2.7 3 0 0 3 3 3 1 Ring finger domain zf-nanos PF05741.8 ETO04982.1 - 0.085 12.8 2.1 5 7.1 0.6 2.7 2 0 0 2 2 2 0 Nanos RNA binding domain zf-C3HC4 PF00097.20 ETO04982.1 - 2 8.1 5.4 18 5.1 0.0 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.27 ETO04983.1 - 2.1e-09 36.9 17.6 0.005 16.6 0.1 6.2 3 3 1 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO04983.1 - 0.006 14.7 0.1 0.02 13.0 0.1 1.7 1 1 0 1 1 1 1 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO04983.1 - 0.047 13.3 2.0 1.8 8.2 0.1 2.9 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A Kinesin PF00225.18 ETO04986.1 - 1.6e-38 132.2 0.4 1.6e-38 132.2 0.3 1.7 2 0 0 2 2 2 1 Kinesin motor domain EF-hand_1 PF00036.27 ETO04986.1 - 0.0023 17.0 1.8 0.0029 16.7 0.2 2.1 2 0 0 2 2 2 1 EF hand EzrA PF06160.7 ETO04986.1 - 0.004 15.4 6.4 0.0084 14.3 4.5 1.4 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA EF-hand_7 PF13499.1 ETO04986.1 - 0.0042 17.1 0.1 0.019 15.0 0.1 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO04986.1 - 0.0085 15.8 0.1 0.037 13.8 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain COG5 PF10392.4 ETO04986.1 - 0.065 13.1 3.9 0.18 11.7 2.7 1.7 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Peptidase_A3 PF02160.10 ETO04986.1 - 2.3 7.7 6.6 7.2 6.1 2.1 2.4 2 0 0 2 2 2 0 Cauliflower mosaic virus peptidase (A3) PyrI PF01948.13 ETO04987.1 - 0.043 13.8 0.6 5.1 7.1 0.1 2.1 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, allosteric domain Tmemb_9 PF05434.6 ETO04988.1 - 0.0039 16.9 0.1 0.0039 16.9 0.1 1.5 1 1 1 2 2 2 1 TMEM9 DUF788 PF05620.6 ETO04988.1 - 0.024 14.5 0.7 0.024 14.5 0.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF788) Herpes_LMP1 PF05297.6 ETO04988.1 - 0.25 10.2 4.9 0.32 9.8 3.4 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) LMF1 PF06762.9 ETO04988.1 - 3.2 6.4 7.7 3.5 6.3 5.3 1.1 1 0 0 1 1 1 0 Lipase maturation factor Kinesin PF00225.18 ETO04989.1 - 3.4 6.2 10.6 3.4 6.2 2.4 2.1 2 0 0 2 2 2 0 Kinesin motor domain DUF2379 PF09543.5 ETO04991.1 - 0.0028 17.5 0.1 0.0047 16.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2379) HSBP1 PF06825.7 ETO04991.1 - 0.015 14.8 1.7 0.035 13.6 1.1 1.8 1 1 0 1 1 1 0 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.4 ETO04991.1 - 0.12 11.7 0.9 0.34 10.3 0.4 1.9 1 1 1 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Prefoldin PF02996.12 ETO04991.1 - 0.18 11.4 2.1 0.39 10.3 1.5 1.5 1 0 0 1 1 1 0 Prefoldin subunit Prefoldin_3 PF13758.1 ETO04991.1 - 0.35 10.6 3.5 0.71 9.6 2.4 1.7 1 1 0 1 1 1 0 Prefoldin subunit CH PF00307.26 ETO04992.1 - 3.2e-07 30.3 1.5 9.4e-07 28.8 0.3 2.2 1 1 1 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 ETO04992.1 - 0.00083 18.9 0.7 0.0071 15.9 0.0 2.8 2 1 2 4 4 4 1 CAMSAP CH domain DUF2305 PF10230.4 ETO04992.1 - 0.14 11.5 1.5 0.23 10.8 0.4 1.7 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2305) LRS4 PF10422.4 ETO04992.1 - 0.15 11.3 6.6 0.2 10.9 4.6 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Syntaxin-6_N PF09177.6 ETO04992.1 - 0.91 9.9 5.5 1.7 9.0 3.7 1.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF4094 PF13334.1 ETO04992.1 - 2.2 8.7 5.3 0.91 9.9 1.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) FAA_hydrolase PF01557.13 ETO04993.1 - 1.6e-07 31.0 0.0 1.6e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 ETO04994.1 - 7.9e-30 103.0 0.0 1e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal FAA_hydrolase PF01557.13 ETO04994.1 - 9e-12 44.9 0.0 1.3e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family mRNA_cap_enzyme PF01331.14 ETO04995.1 - 9.3e-24 84.1 10.4 1.5e-22 80.2 2.8 2.8 3 0 0 3 3 3 2 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.16 ETO04995.1 - 1.5e-06 27.6 0.6 0.01 15.2 0.1 2.6 1 1 1 2 2 2 2 ATP dependent DNA ligase domain mRNA_cap_C PF03919.10 ETO04995.1 - 3.4e-06 27.3 2.8 3.3e-05 24.1 0.0 2.7 2 1 0 2 2 2 1 mRNA capping enzyme, C-terminal domain F5_F8_type_C PF00754.20 ETO04995.1 - 0.053 13.3 0.1 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 F5/8 type C domain Sulfotransfer_2 PF03567.9 ETO04998.1 - 2.3e-08 34.0 0.3 2.9e-08 33.7 0.2 1.3 1 0 0 1 1 1 1 Sulfotransferase family DUF4361 PF14274.1 ETO04998.1 - 0.72 9.4 4.6 0.11 12.1 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4361) RhoGEF PF00621.15 ETO04999.1 - 4.1e-16 59.3 1.6 5.3e-16 59.0 1.1 1.1 1 0 0 1 1 1 1 RhoGEF domain AAA_22 PF13401.1 ETO05001.1 - 0.00037 20.6 0.0 0.0077 16.3 0.0 3.1 3 1 0 3 3 3 1 AAA domain AAA PF00004.24 ETO05001.1 - 0.089 12.9 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETO05001.1 - 0.1 12.2 0.0 0.96 9.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Pkinase PF00069.20 ETO05002.1 - 7e-06 25.3 0.1 9.3e-06 24.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO05002.1 - 0.0026 16.8 0.0 0.0034 16.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase HSBP1 PF06825.7 ETO05003.1 - 0.076 12.5 0.1 12 5.5 0.0 2.7 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Protamine_P2 PF00841.14 ETO05004.1 - 0.055 14.0 0.4 0.11 13.0 0.2 1.6 1 0 0 1 1 1 0 Sperm histone P2 NACHT PF05729.7 ETO05005.1 - 6.5e-09 35.6 0.2 2e-07 30.8 0.2 2.3 1 1 0 1 1 1 1 NACHT domain Mg_chelatase PF01078.16 ETO05005.1 - 0.00014 21.0 0.0 0.002 17.2 0.0 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 ETO05005.1 - 0.00024 21.1 0.0 0.00082 19.4 0.0 1.7 1 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 ETO05005.1 - 0.00068 19.0 0.0 0.0017 17.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 ETO05005.1 - 0.00077 18.3 0.5 0.0022 16.8 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.1 ETO05005.1 - 0.0031 17.6 0.1 0.0069 16.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain DUF87 PF01935.12 ETO05005.1 - 0.0076 16.0 0.4 0.025 14.4 0.1 1.9 1 1 1 2 2 2 1 Domain of unknown function DUF87 SMC_N PF02463.14 ETO05005.1 - 0.0094 15.1 0.2 0.095 11.9 0.0 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain eIF2A PF08662.6 ETO05005.1 - 0.013 15.2 0.4 0.018 14.7 0.3 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A AAA_18 PF13238.1 ETO05005.1 - 0.018 15.3 2.6 0.024 14.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 ETO05005.1 - 0.043 13.9 1.8 0.12 12.5 0.1 2.5 2 1 0 2 2 2 0 RNA helicase ABC_tran PF00005.22 ETO05005.1 - 0.084 13.1 0.0 0.23 11.7 0.0 1.8 2 0 0 2 2 2 0 ABC transporter AAA_10 PF12846.2 ETO05005.1 - 0.096 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Sigma54_activat PF00158.21 ETO05005.1 - 0.12 11.8 0.0 0.29 10.5 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain WD40 PF00400.27 ETO05006.1 - 1.1e-60 199.4 15.9 3.4e-12 45.7 0.0 8.3 8 0 0 8 8 8 6 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO05006.1 - 1.7e-06 27.9 3.9 0.002 18.2 0.0 5.1 5 0 0 5 5 5 1 Kelch motif Cytochrom_D1 PF02239.11 ETO05006.1 - 2.1e-05 23.0 2.2 0.0098 14.2 0.0 3.1 1 1 1 3 3 3 2 Cytochrome D1 heme domain Kelch_4 PF13418.1 ETO05006.1 - 0.00077 19.1 2.0 0.046 13.4 0.1 3.7 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO05006.1 - 0.0025 17.3 11.8 0.045 13.3 0.0 4.1 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 ETO05006.1 - 0.004 17.2 0.6 0.077 13.1 0.0 2.9 3 0 0 3 3 3 1 Galactose oxidase, central domain PLD_C PF12357.3 ETO05006.1 - 0.039 13.4 0.5 14 5.3 0.0 4.5 5 1 1 6 6 6 0 Phospholipase D C terminal PQQ_2 PF13360.1 ETO05006.1 - 0.042 13.3 0.1 0.098 12.1 0.1 1.6 1 0 0 1 1 1 0 PQQ-like domain TPR_12 PF13424.1 ETO05007.1 - 7e-183 593.0 83.6 5.9e-20 70.9 0.6 12.6 5 3 6 14 14 14 14 Tetratricopeptide repeat TPR_11 PF13414.1 ETO05007.1 - 3.4e-114 372.5 88.2 6.4e-14 51.3 2.1 13.0 10 3 2 12 12 12 12 TPR repeat TPR_1 PF00515.23 ETO05007.1 - 1.7e-109 353.3 140.7 4.3e-08 32.4 0.7 22.0 22 0 0 22 22 22 20 Tetratricopeptide repeat TPR_10 PF13374.1 ETO05007.1 - 1.1e-104 339.7 0.0 2e-08 33.9 0.0 20.0 21 0 0 21 21 20 17 Tetratricopeptide repeat TPR_2 PF07719.12 ETO05007.1 - 1.2e-87 280.9 110.2 2.3e-06 27.1 0.0 21.9 22 0 0 22 22 22 18 Tetratricopeptide repeat TPR_7 PF13176.1 ETO05007.1 - 2.3e-83 267.5 49.9 9.4e-08 31.3 0.0 20.1 21 0 0 21 21 19 16 Tetratricopeptide repeat TPR_8 PF13181.1 ETO05007.1 - 3.2e-53 173.5 128.9 0.00012 21.6 0.2 21.7 21 0 0 21 21 21 15 Tetratricopeptide repeat TPR_16 PF13432.1 ETO05007.1 - 5.4e-39 132.0 8.7 6.1e-06 26.7 0.0 12.9 11 2 3 14 14 13 8 Tetratricopeptide repeat TPR_17 PF13431.1 ETO05007.1 - 2.1e-34 114.7 59.4 0.00075 19.5 0.1 20.3 20 0 0 20 20 20 8 Tetratricopeptide repeat TPR_6 PF13174.1 ETO05007.1 - 1.1e-25 88.2 22.9 0.013 15.8 0.0 17.4 19 0 0 19 19 19 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO05007.1 - 6e-24 82.3 0.0 0.28 11.9 0.0 14.2 15 1 1 16 16 14 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO05007.1 - 2e-14 53.4 98.5 0.028 14.5 0.7 13.6 1 1 13 15 15 15 11 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO05007.1 - 1.8e-13 50.5 9.9 0.48 10.8 0.0 10.2 8 2 3 12 12 12 4 Tetratricopeptide repeat PPR PF01535.15 ETO05007.1 - 5.9e-08 32.1 60.1 0.095 12.7 0.1 14.4 16 0 0 16 16 15 6 PPR repeat SHNi-TPR PF10516.4 ETO05007.1 - 3.8e-07 29.2 20.3 1.2 8.4 0.0 12.1 14 0 0 14 14 14 1 SHNi-TPR Kelch_6 PF13964.1 ETO05007.1 - 2.2e-06 27.5 3.8 0.034 14.3 0.4 4.0 3 0 0 3 3 3 2 Kelch motif TPR_3 PF07720.7 ETO05007.1 - 2.6e-05 23.8 96.2 0.026 14.3 0.1 15.1 17 0 0 17 17 16 5 Tetratricopeptide repeat Kelch_3 PF13415.1 ETO05007.1 - 0.00086 19.4 0.2 0.011 15.8 0.0 2.8 3 0 0 3 3 2 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO05007.1 - 0.0031 17.0 9.4 0.48 9.9 1.8 3.5 3 0 0 3 3 2 2 Kelch motif TPR_9 PF13371.1 ETO05007.1 - 0.0032 17.2 0.1 4.3 7.2 0.0 5.0 4 1 0 4 4 4 1 Tetratricopeptide repeat DUF2164 PF09932.4 ETO05007.1 - 0.11 12.2 10.5 25 4.7 0.0 5.5 5 0 0 5 5 5 0 Uncharacterized conserved protein (DUF2164) PPR_1 PF12854.2 ETO05007.1 - 0.71 9.4 6.7 65 3.1 0.0 5.2 7 0 0 7 7 6 0 PPR repeat Tetraspannin PF00335.15 ETO05008.1 - 4.1 6.6 12.0 8.1 5.6 8.3 1.4 1 0 0 1 1 1 0 Tetraspanin family WD40 PF00400.27 ETO05010.1 - 4.8e-63 206.9 4.4 1.1e-12 47.3 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO05010.1 - 5.8e-09 35.9 0.9 0.00095 18.9 0.1 2.8 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO05010.1 - 4.4e-07 28.5 0.1 0.00059 18.2 0.0 2.7 2 1 1 3 3 3 2 Cytochrome D1 heme domain PD40 PF07676.7 ETO05010.1 - 9.3e-05 21.9 8.8 0.66 9.6 0.0 6.1 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.9 ETO05010.1 - 0.00033 19.5 0.8 0.034 12.9 0.0 2.1 1 1 0 2 2 2 2 Coatomer WD associated region Nucleoporin_N PF08801.6 ETO05010.1 - 0.0049 15.6 7.3 0.32 9.7 1.5 3.8 1 1 0 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 ETO05010.1 - 0.0073 14.4 0.1 1 7.4 0.0 3.2 2 1 0 2 2 2 1 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO05010.1 - 0.015 14.7 0.0 0.12 11.8 0.0 2.1 1 1 1 2 2 2 0 PQQ-like domain DUF1258 PF06869.7 ETO05010.1 - 0.04 13.0 2.7 5.7 5.9 0.0 3.0 2 2 1 3 3 3 0 Protein of unknown function (DUF1258) Proteasome_A_N PF10584.4 ETO05010.1 - 0.32 10.3 2.5 40 3.6 0.0 3.8 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Kelch_4 PF13418.1 ETO05011.1 - 1.2e-08 34.5 1.4 0.00023 20.8 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO05011.1 - 1.6e-07 30.7 15.9 8.7e-07 28.3 0.3 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO05011.1 - 3.3e-06 27.0 10.5 0.00069 19.6 0.1 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO05011.1 - 0.0002 20.9 6.9 0.0063 16.2 0.2 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO05011.1 - 0.00023 21.2 0.4 0.034 14.3 0.0 2.6 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO05011.1 - 0.052 13.5 0.4 0.052 13.5 0.3 4.1 5 0 0 5 5 5 0 Kelch motif zf-RING_5 PF14634.1 ETO05013.1 - 0.0014 18.3 5.2 0.0023 17.6 3.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 ETO05013.1 - 0.0097 15.5 6.9 0.017 14.7 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO05013.1 - 0.011 15.6 4.2 0.02 14.9 2.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS91 PF14319.1 ETO05013.1 - 0.017 14.6 1.3 0.032 13.7 0.9 1.4 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-Apc11 PF12861.2 ETO05013.1 - 0.021 14.6 0.6 0.037 13.8 0.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 ETO05013.1 - 0.024 14.4 6.4 0.041 13.7 4.5 1.3 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.1 ETO05013.1 - 0.095 12.4 5.2 0.19 11.4 3.3 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.1 ETO05013.1 - 0.096 12.3 4.9 0.15 11.7 3.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3944 PF13099.1 ETO05014.1 - 0.056 12.9 1.7 0.15 11.5 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3944) SGL PF08450.7 ETO05016.1 - 2.7e-06 26.9 0.2 0.0011 18.4 0.0 1.7 1 1 1 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region RNA_pol_L_2 PF13656.1 ETO05017.1 - 0.079 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Actin PF00022.14 ETO05018.1 - 0.0097 14.3 0.0 0.01 14.3 0.0 1.1 1 0 0 1 1 1 1 Actin DUF1340 PF07067.6 ETO05018.1 - 0.012 14.8 0.1 0.014 14.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) Peptidase_C50 PF03568.12 ETO05018.1 - 0.03 12.9 1.0 0.031 12.9 0.7 1.0 1 0 0 1 1 1 0 Peptidase family C50 zf-TRAF PF02176.13 ETO05019.1 - 1.7e-05 25.0 3.0 4.4e-05 23.7 0.3 2.3 2 1 0 2 2 2 1 TRAF-type zinc finger ADIP PF11559.3 ETO05019.1 - 0.017 15.0 2.1 0.022 14.6 1.5 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Ribosomal_S19e PF01090.14 ETO05020.1 - 2.7e-23 81.9 1.2 5e-23 81.0 0.9 1.4 1 0 0 1 1 1 1 Ribosomal protein S19e DUF3521 PF12035.3 ETO05020.1 - 0.017 14.9 2.8 0.27 11.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3521) HTH_12 PF08461.5 ETO05020.1 - 0.079 12.7 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain DUF349 PF03993.7 ETO05020.1 - 0.9 9.7 8.1 1.3 9.2 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) LicD PF04991.8 ETO05021.1 - 0.011 15.9 2.5 0.022 14.8 1.8 1.5 1 1 0 1 1 1 0 LicD family dsDNA_bind PF01984.15 ETO05022.1 - 0.086 12.8 2.7 0.11 12.5 0.6 2.0 2 0 0 2 2 2 0 Double-stranded DNA-binding domain Drf_GBD PF06371.8 ETO05024.1 - 2.5e-10 40.0 0.7 9e-10 38.2 0.5 2.0 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH1 PF06346.7 ETO05024.1 - 0.0004 19.9 120.0 0.017 14.6 46.4 2.2 1 1 1 2 2 2 2 Formin Homology Region 1 IncA PF04156.9 ETO05024.1 - 0.058 12.9 3.2 0.13 11.8 2.2 1.6 1 0 0 1 1 1 0 IncA protein DMPK_coil PF08826.5 ETO05024.1 - 0.37 10.7 7.9 6.7 6.6 0.1 2.7 1 1 0 2 2 2 0 DMPK coiled coil domain like Cytadhesin_P30 PF07271.6 ETO05024.1 - 3 7.0 54.9 0.034 13.4 14.2 3.2 1 1 2 3 3 3 0 Cytadhesin P30/P32 Drf_GBD PF06371.8 ETO05025.1 - 1.9e-08 33.8 1.3 2.3e-08 33.6 0.9 1.1 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain DUF1673 PF07895.6 ETO05026.1 - 0.029 13.8 1.4 2.9 7.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) zf-rbx1 PF12678.2 ETO05027.1 - 3.8e-09 36.5 5.6 8.8e-09 35.3 3.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 ETO05027.1 - 0.00028 20.6 6.4 0.00059 19.6 4.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger ubiquitin PF00240.18 ETO05027.1 - 0.0018 17.6 1.7 0.0042 16.4 0.8 2.0 1 1 1 2 2 2 1 Ubiquitin family LeuA_dimer PF08502.5 ETO05027.1 - 0.018 14.8 0.1 0.033 13.9 0.1 1.4 1 0 0 1 1 1 0 LeuA allosteric (dimerisation) domain zf-RING_2 PF13639.1 ETO05027.1 - 0.055 13.2 9.6 0.14 12.0 6.7 1.8 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 ETO05027.1 - 0.65 10.0 6.6 2.6 8.1 4.6 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3H1 PF10650.4 ETO05027.1 - 2.4 7.7 5.2 2.3 7.7 0.8 3.0 3 0 0 3 3 3 0 Putative zinc-finger domain PNK3P PF08645.6 ETO05028.1 - 0.0086 15.5 0.1 0.013 14.9 0.1 1.4 1 1 0 1 1 1 1 Polynucleotide kinase 3 phosphatase DUF416 PF04222.7 ETO05028.1 - 0.059 12.5 0.1 0.07 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF416) WD40 PF00400.27 ETO05031.1 - 1.9e-50 167.0 19.0 2.7e-13 49.2 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO05031.1 - 8.5e-08 30.7 0.1 1.2 7.2 0.0 4.1 1 1 3 4 4 4 4 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO05031.1 - 0.023 14.6 0.0 2.1 8.3 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3601) PQQ_2 PF13360.1 ETO05031.1 - 0.1 12.0 0.0 0.83 9.0 0.0 2.3 2 1 1 3 3 3 0 PQQ-like domain Kelch_1 PF01344.20 ETO05032.1 - 2.3e-10 39.8 1.4 1.2e-06 27.9 0.3 4.2 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 ETO05032.1 - 3.8e-08 32.7 7.5 5.9e-05 22.6 0.1 5.0 5 1 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 ETO05032.1 - 2.5e-07 30.5 5.2 0.0096 16.0 0.1 5.0 4 1 1 5 5 5 2 Kelch motif Kelch_3 PF13415.1 ETO05032.1 - 7.5e-05 22.7 0.2 0.014 15.5 0.0 3.5 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO05032.1 - 0.00011 22.0 3.8 1.5 8.8 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 ETO05032.1 - 0.0031 17.2 0.9 0.17 11.6 0.0 3.3 2 1 1 3 3 3 1 Galactose oxidase, central domain hGDE_N PF14699.1 ETO05032.1 - 0.028 14.2 0.1 0.58 10.0 0.0 2.5 2 0 0 2 2 2 0 N-terminal domain from the human glycogen debranching enzyme Aminotran_1_2 PF00155.16 ETO05034.1 - 5.3e-19 68.3 0.0 7.1e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 ETO05034.1 - 1.2e-06 27.9 0.0 2e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 ETO05034.1 - 0.0091 14.3 0.1 0.019 13.2 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 ETO05034.1 - 0.14 11.1 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Siah-Interact_N PF09032.6 ETO05034.1 - 3.3 7.8 6.0 4.2 7.4 0.1 3.2 3 1 1 4 4 4 0 Siah interacting protein, N terminal DUF3609 PF12259.3 ETO05038.1 - 0.0024 16.5 0.1 0.0037 15.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3609) Sigma_reg_N PF13800.1 ETO05038.1 - 0.008 16.1 0.1 0.016 15.2 0.1 1.6 1 0 0 1 1 1 1 Sigma factor regulator N-terminal Protocadherin PF08374.6 ETO05038.1 - 0.022 14.4 0.6 0.022 14.4 0.4 2.2 1 1 1 2 2 2 0 Protocadherin TarH PF02203.10 ETO05038.1 - 0.03 14.1 0.3 0.06 13.1 0.0 1.7 2 0 0 2 2 2 0 Tar ligand binding domain homologue Fijivirus_P9-2 PF06837.6 ETO05038.1 - 0.046 12.8 0.0 0.082 12.0 0.0 1.4 1 0 0 1 1 1 0 Fijivirus P9-2 protein DUF2422 PF10337.4 ETO05038.1 - 0.074 11.8 0.5 0.15 10.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) FxsA PF04186.8 ETO05038.1 - 0.085 12.4 0.3 0.15 11.6 0.2 1.3 1 0 0 1 1 1 0 FxsA cytoplasmic membrane protein DUF1049 PF06305.6 ETO05038.1 - 0.13 11.7 0.1 0.13 11.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) IncA PF04156.9 ETO05038.1 - 0.16 11.5 0.0 0.16 11.5 0.0 1.6 2 0 0 2 2 2 0 IncA protein DUF3810 PF12725.2 ETO05038.1 - 0.19 10.6 1.3 0.19 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Neur_chan_memb PF02932.11 ETO05038.1 - 0.6 9.9 11.8 6 6.6 8.2 2.0 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MLANA PF14991.1 ETO05038.1 - 0.71 9.9 3.1 0.66 10.0 0.2 2.1 2 1 0 2 2 2 0 Protein melan-A DUF1754 PF08555.5 ETO05038.1 - 0.83 10.2 15.2 26 5.4 10.5 2.3 1 1 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) RNA_pol_L_2 PF13656.1 ETO05041.1 - 8.8e-21 73.1 0.0 1.5e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF640 PF04852.7 ETO05041.1 - 0.036 14.2 0.1 0.036 14.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF640) RNA_pol_L PF01193.19 ETO05041.1 - 0.042 12.9 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain CD36 PF01130.16 ETO05042.1 - 9.5e-24 83.5 6.6 1.3e-23 83.0 4.5 1.1 1 0 0 1 1 1 1 CD36 family ubiquitin PF00240.18 ETO05044.1 - 3e-17 61.7 0.1 5.6e-17 60.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 ETO05044.1 - 1.3e-11 43.9 0.3 2.9e-11 42.8 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 ETO05044.1 - 2.1e-05 24.6 0.1 3.7e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.4 ETO05044.1 - 0.014 15.5 1.0 0.032 14.4 0.3 1.9 1 1 1 2 2 2 0 DUF2407 ubiquitin-like domain CobT PF06213.7 ETO05045.1 - 0.0024 17.0 12.5 0.0037 16.4 8.7 1.3 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT ubiquitin PF00240.18 ETO05046.1 - 0.00024 20.4 0.1 0.00072 18.9 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 ETO05046.1 - 0.065 13.4 0.2 0.065 13.4 0.2 2.4 2 1 0 2 2 2 0 DUF2407 ubiquitin-like domain RRM_6 PF14259.1 ETO05047.1 - 4.9e-09 36.0 0.0 1.2e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO05047.1 - 5.3e-06 25.9 0.1 1.4e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO05047.1 - 0.037 13.8 0.4 0.47 10.3 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pox_A14 PF05767.7 ETO05047.1 - 0.05 13.5 0.2 0.12 12.3 0.2 1.6 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 TMEM154 PF15102.1 ETO05047.1 - 0.06 13.0 1.3 0.066 12.9 0.1 1.6 2 0 0 2 2 2 0 TMEM154 protein family EF-hand_6 PF13405.1 ETO05048.1 - 1.9e-07 30.3 0.1 0.016 15.0 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 ETO05048.1 - 7.5e-07 29.1 1.5 0.094 12.8 0.1 4.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 ETO05048.1 - 3.3e-05 22.8 0.5 0.007 15.5 0.0 3.6 3 0 0 3 3 3 1 EF hand RPEL PF02755.10 ETO05048.1 - 0.00015 20.9 0.0 0.014 14.6 0.1 3.2 2 0 0 2 2 2 1 RPEL repeat EF-hand_5 PF13202.1 ETO05048.1 - 0.0016 17.7 0.1 0.0055 16.0 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 ETO05048.1 - 0.019 14.5 0.7 0.11 12.1 0.1 2.7 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_7 PF13499.1 ETO05049.1 - 0.00038 20.5 0.5 0.001 19.1 0.3 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO05049.1 - 0.00095 18.3 0.8 0.0083 15.3 0.2 2.6 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 ETO05049.1 - 0.0011 18.6 1.5 0.0044 16.7 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 ETO05049.1 - 0.004 16.4 0.3 0.0098 15.2 0.2 1.7 1 0 0 1 1 1 1 EF hand Ribosomal_L50 PF10501.4 ETO05050.1 - 0.011 15.6 0.3 0.011 15.6 0.2 3.8 4 1 1 5 5 5 0 Ribosomal subunit 39S DUF1018 PF06252.7 ETO05050.1 - 0.044 14.2 3.4 0.47 10.9 0.0 4.0 3 2 1 4 4 4 0 Protein of unknown function (DUF1018) Homeobox_KN PF05920.6 ETO05050.1 - 0.08 12.6 0.1 0.44 10.3 0.0 2.3 2 0 0 2 2 2 0 Homeobox KN domain DUF2267 PF10025.4 ETO05050.1 - 0.082 12.9 0.1 19 5.3 0.0 3.3 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2267) ATP-synt_F6 PF05511.6 ETO05050.1 - 0.56 10.1 6.3 2 8.3 0.3 3.8 3 0 0 3 3 3 0 Mitochondrial ATP synthase coupling factor 6 Cytochrom_B562 PF07361.6 ETO05050.1 - 0.6 10.5 18.5 0.73 10.2 1.6 5.1 4 2 0 4 4 4 0 Cytochrome b562 Phasin_2 PF09361.5 ETO05050.1 - 1.8 8.6 6.3 11 6.1 0.0 3.9 4 0 0 4 4 4 0 Phasin protein HSBP1 PF06825.7 ETO05050.1 - 2.4 7.7 15.4 1.1 8.8 0.1 5.6 7 0 0 7 7 7 0 Heat shock factor binding protein 1 zf-TRAF PF02176.13 ETO05051.1 - 0.00022 21.5 0.5 0.00022 21.5 0.3 2.8 3 0 0 3 3 3 2 TRAF-type zinc finger Cortex-I_coil PF09304.5 ETO05054.1 - 0.014 15.4 3.7 0.014 15.4 2.6 2.7 1 1 0 2 2 2 0 Cortexillin I, coiled coil DUF1843 PF08898.5 ETO05054.1 - 0.36 10.9 1.7 1.4 8.9 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Spectrin PF00435.16 ETO05054.1 - 0.48 10.7 9.4 0.07 13.4 3.5 1.8 2 0 0 2 2 2 0 Spectrin repeat Taxilin PF09728.4 ETO05054.1 - 1.2 8.0 33.0 2.5 7.0 22.3 1.8 1 1 0 1 1 1 0 Myosin-like coiled-coil protein Nup54 PF13874.1 ETO05054.1 - 2.8 7.5 10.7 1.2 8.8 5.2 1.9 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 YlqD PF11068.3 ETO05054.1 - 9 6.3 16.8 0.17 11.9 5.1 2.6 1 1 2 3 3 3 0 YlqD protein Kelch_6 PF13964.1 ETO05056.1 - 1.6e-06 28.0 7.2 0.026 14.7 0.1 4.1 3 1 1 4 4 4 3 Kelch motif Kelch_1 PF01344.20 ETO05056.1 - 0.00082 18.8 6.5 0.25 10.9 0.7 2.9 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.1 ETO05056.1 - 0.0055 16.6 0.4 10 6.2 0.1 3.6 3 0 0 3 3 3 1 Kelch motif 2Fe-2S_thioredx PF01257.14 ETO05056.1 - 0.012 15.1 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin Kelch_2 PF07646.10 ETO05056.1 - 0.021 14.5 0.3 0.021 14.5 0.2 3.6 4 0 0 4 4 4 0 Kelch motif Kelch_3 PF13415.1 ETO05056.1 - 0.043 13.9 0.2 8.5 6.6 0.0 3.1 2 1 0 2 2 2 0 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO05056.1 - 0.14 11.9 6.8 1.9 8.2 0.1 3.9 5 0 0 5 5 5 0 Galactose oxidase, central domain WD40 PF00400.27 ETO05057.1 - 4.6e-11 42.1 6.3 7.8e-11 41.4 1.8 2.4 2 0 0 2 2 2 1 WD domain, G-beta repeat WD40 PF00400.27 ETO05058.1 - 2.4e-17 62.0 3.0 2.8e-10 39.6 0.1 3.4 3 1 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO05058.1 - 0.00045 18.4 0.3 0.35 8.9 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Receptor_2B4 PF11465.3 ETO05058.1 - 0.073 13.0 0.1 0.095 12.6 0.1 1.3 1 1 0 1 1 1 0 Natural killer cell receptor 2B4 Nucleoporin_N PF08801.6 ETO05058.1 - 0.079 11.6 0.4 0.29 9.8 0.3 1.8 1 1 0 1 1 1 0 Nup133 N terminal like DUF1759 PF03564.10 ETO05060.1 - 0.024 14.4 1.6 0.028 14.2 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1759) RPOL_N PF14700.1 ETO05062.1 - 0.096 11.9 6.1 0.12 11.6 4.2 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal RNA_pol_Rpb1_5 PF04998.12 ETO05062.1 - 0.68 9.1 10.3 0.83 8.8 7.1 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF1980 PF09323.5 ETO05062.1 - 1 9.1 8.0 0.14 11.8 2.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) Sin3_corepress PF08295.7 ETO05062.1 - 2.3 8.0 9.7 4.5 7.0 2.3 2.7 2 1 1 3 3 3 0 Sin3 family co-repressor Seryl_tRNA_N PF02403.17 ETO05062.1 - 2.8 8.0 12.3 7.7 6.5 0.0 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Elf1 PF05129.8 ETO05063.1 - 0.0057 16.3 0.1 0.014 15.0 0.1 1.7 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Occludin_ELL PF07303.8 ETO05065.1 - 0.032 14.9 9.6 0.067 13.9 6.6 1.5 1 0 0 1 1 1 0 Occludin homology domain DUF1751 PF08551.5 ETO05065.1 - 0.093 13.0 0.1 0.18 12.1 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) DUF287 PF03384.9 ETO05065.1 - 0.25 11.5 0.3 0.25 11.5 0.2 2.7 1 1 2 3 3 3 0 Drosophila protein of unknown function, DUF287 Glyoxalase_2 PF12681.2 ETO05066.1 - 7.1e-14 52.3 0.0 9.7e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 ETO05066.1 - 0.0014 18.6 0.0 0.0078 16.1 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Ykof PF07615.6 ETO05066.1 - 0.073 13.2 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 YKOF-related Family DUF1191 PF06697.7 ETO05067.1 - 0.036 12.8 0.2 0.093 11.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) zf-CCHC PF00098.18 ETO05067.1 - 0.08 12.9 1.0 0.08 12.9 0.7 3.2 3 0 0 3 3 3 0 Zinc knuckle DUF2353 PF09789.4 ETO05069.1 - 0.0056 15.9 3.3 0.0072 15.6 2.3 1.2 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) CCDC155 PF14662.1 ETO05069.1 - 0.0085 15.7 8.9 0.011 15.2 6.2 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 DUF632 PF04782.7 ETO05069.1 - 0.018 14.1 1.5 0.022 13.8 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF632) DUF3972 PF13118.1 ETO05069.1 - 0.019 15.0 5.1 0.087 12.9 3.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3972) RE_AlwI PF09491.5 ETO05069.1 - 0.022 13.2 6.9 0.024 13.1 4.8 1.0 1 0 0 1 1 1 0 AlwI restriction endonuclease Lipoprotein_20 PF13942.1 ETO05069.1 - 0.039 13.5 3.0 0.049 13.1 1.8 1.3 1 1 0 1 1 1 0 YfhG lipoprotein DUF2570 PF10828.3 ETO05069.1 - 0.06 12.9 4.7 0.29 10.7 2.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) HOOK PF05622.7 ETO05069.1 - 0.067 10.9 6.2 0.085 10.6 4.3 1.1 1 0 0 1 1 1 0 HOOK protein DivIC PF04977.10 ETO05069.1 - 0.12 11.9 3.7 0.18 11.3 1.6 2.0 1 1 1 2 2 2 0 Septum formation initiator CENP-F_leu_zip PF10473.4 ETO05069.1 - 0.17 11.7 7.2 0.06 13.2 2.9 1.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_CLD_2 PF14197.1 ETO05069.1 - 0.31 11.0 3.9 2.1 8.3 2.5 2.3 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Kinesin-relat_1 PF12711.2 ETO05069.1 - 0.39 11.1 7.9 0.4 11.1 0.6 3.1 1 1 2 3 3 3 0 Kinesin motor DUF904 PF06005.7 ETO05069.1 - 1 9.7 11.0 4 7.8 6.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF904) IncA PF04156.9 ETO05069.1 - 1.3 8.5 6.7 1.7 8.2 4.6 1.1 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 ETO05069.1 - 1.4 8.8 9.1 1 9.1 3.3 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.16 ETO05069.1 - 3.3 7.7 8.3 2.4 8.1 0.9 2.9 1 1 2 3 3 3 0 bZIP transcription factor DUF972 PF06156.8 ETO05069.1 - 4.1 7.7 8.3 6 7.2 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) EF-hand_7 PF13499.1 ETO05070.1 - 5.6e-11 42.4 1.8 1.2e-10 41.3 0.2 2.3 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO05070.1 - 2.4e-10 38.9 2.4 0.00031 19.8 0.5 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 ETO05070.1 - 3.5e-09 36.1 0.3 0.0015 18.1 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO05070.1 - 4.4e-07 29.2 3.8 0.0099 15.6 0.3 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 ETO05070.1 - 1.5e-05 24.0 1.4 0.019 14.2 0.0 2.8 2 0 0 2 2 2 2 EF hand KLRAQ PF10205.4 ETO05070.1 - 0.00095 19.1 6.0 0.00095 19.1 4.2 2.3 2 0 0 2 2 2 1 Predicted coiled-coil domain-containing protein SPARC_Ca_bdg PF10591.4 ETO05070.1 - 0.0013 18.7 0.5 0.0013 18.7 0.3 3.4 2 1 2 4 4 4 1 Secreted protein acidic and rich in cysteine Ca binding region DUF496 PF04363.7 ETO05070.1 - 0.0043 16.8 0.3 0.012 15.4 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF496) EF-hand_9 PF14658.1 ETO05070.1 - 0.0088 15.9 0.1 5.5 6.9 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain DUF4164 PF13747.1 ETO05070.1 - 0.051 13.7 5.0 0.12 12.5 3.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Tox-REase-5 PF15648.1 ETO05070.1 - 0.083 13.1 4.6 0.089 13.0 0.3 2.6 2 1 0 2 2 2 0 Restriction endonuclease fold toxin 5 Consortin_C PF15281.1 ETO05070.1 - 0.087 12.3 0.1 0.24 10.9 0.1 1.7 1 0 0 1 1 1 0 Consortin C-terminus DIL PF01843.14 ETO05070.1 - 0.18 11.6 2.9 16 5.4 1.7 3.0 2 1 1 3 3 3 0 DIL domain Sec20 PF03908.8 ETO05070.1 - 0.66 9.7 4.8 0.4 10.4 1.2 2.2 3 0 0 3 3 2 0 Sec20 DUF3641 PF12345.3 ETO05070.1 - 1 9.2 5.3 0.27 11.0 0.9 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3641) DUF4485 PF14846.1 ETO05070.1 - 1.6 8.5 5.9 1.2 8.8 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4485) CASP_C PF08172.7 ETO05070.1 - 2.2 7.2 12.4 0.15 11.0 4.9 1.8 2 1 0 2 2 2 0 CASP C terminal DivIC PF04977.10 ETO05070.1 - 2.8 7.5 18.9 0.24 10.9 3.5 3.6 3 1 2 5 5 5 0 Septum formation initiator Seryl_tRNA_N PF02403.17 ETO05070.1 - 3.8 7.5 14.7 0.25 11.3 5.1 2.6 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HALZ PF02183.13 ETO05070.1 - 4.6 7.0 18.9 3.2 7.5 3.6 4.2 3 1 1 4 4 4 0 Homeobox associated leucine zipper Retrotrans_gag PF03732.12 ETO05070.1 - 6.1 6.9 8.7 3.6 7.7 2.6 2.6 2 1 1 3 3 3 0 Retrotransposon gag protein DUF972 PF06156.8 ETO05070.1 - 8 6.8 13.1 6.1 7.2 6.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF3513 PF12026.3 ETO05070.1 - 8.9 5.7 13.5 1.1 8.7 4.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3513) WD40 PF00400.27 ETO05072.1 - 1.4e-11 43.7 5.4 0.00056 19.6 0.0 5.4 6 1 0 6 6 6 4 WD domain, G-beta repeat DAGK_cat PF00781.19 ETO05072.1 - 0.1 11.9 0.0 1 8.7 0.0 2.2 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain zf-DHHC PF01529.15 ETO05073.1 - 0.0053 16.1 10.2 0.015 14.7 0.4 2.3 2 0 0 2 2 2 2 DHHC palmitoyltransferase AAA_33 PF13671.1 ETO05074.1 - 0.0015 18.4 0.0 0.0026 17.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain Toxin_57 PF15535.1 ETO05074.1 - 0.058 13.4 0.2 0.11 12.5 0.2 1.4 1 0 0 1 1 1 0 Putative toxin 57 HVSL PF09749.4 ETO05075.1 - 3.8e-39 134.1 5.3 5.1e-39 133.7 3.6 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein POTRA_2 PF08479.6 ETO05075.1 - 0.04 13.5 0.1 1.4 8.6 0.1 2.6 1 1 1 2 2 2 0 POTRA domain, ShlB-type ORC6 PF05460.8 ETO05075.1 - 0.15 11.1 3.9 0.84 8.6 2.7 1.9 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) MVP_shoulder PF11978.3 ETO05076.1 - 0.045 13.6 0.1 0.08 12.8 0.1 1.3 1 0 0 1 1 1 0 Shoulder domain DUF2357 PF09823.4 ETO05076.1 - 0.17 10.9 1.2 0.79 8.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2357) RRS1 PF04939.7 ETO05076.1 - 1.2 8.6 6.1 1.5 8.2 0.1 2.6 2 1 1 3 3 3 0 Ribosome biogenesis regulatory protein (RRS1) ATPgrasp_YheCD PF14398.1 ETO05077.1 - 0.017 13.9 0.0 0.028 13.2 0.0 1.3 1 0 0 1 1 1 0 YheC/D like ATP-grasp RimK PF08443.6 ETO05077.1 - 0.059 12.8 0.1 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Toxin_64 PF15542.1 ETO05077.1 - 0.18 12.4 1.6 0.8 10.3 0.2 2.4 2 0 0 2 2 2 0 Putative toxin 64 SDA1 PF05285.7 ETO05078.1 - 0.0038 16.5 14.0 0.0038 16.5 9.7 1.6 1 1 0 1 1 1 1 SDA1 DUF2457 PF10446.4 ETO05078.1 - 4.8 5.8 15.5 7.9 5.0 10.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NACHT PF05729.7 ETO05079.1 - 0.014 15.0 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 ETO05079.1 - 0.052 13.5 0.0 0.59 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain FDX-ACB PF03147.9 ETO05079.1 - 0.1 12.7 1.3 0.36 11.0 0.9 1.9 1 1 1 2 2 2 0 Ferredoxin-fold anticodon binding domain DUF3911 PF13050.1 ETO05079.1 - 1 9.5 3.6 2.4 8.3 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3911) TPR_2 PF07719.12 ETO05082.1 - 4.2e-08 32.4 0.8 0.024 14.5 0.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO05082.1 - 8.6e-07 28.5 1.7 0.0014 18.1 0.1 3.1 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 ETO05082.1 - 2.6e-06 26.8 4.4 0.054 13.1 0.8 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO05082.1 - 1.1e-05 25.4 5.6 0.00061 19.8 1.0 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO05082.1 - 2.9e-05 24.3 2.9 0.13 12.5 0.1 3.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO05082.1 - 0.00012 21.5 1.5 0.82 9.5 0.2 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETO05082.1 - 0.00015 21.5 0.4 0.0075 16.1 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO05082.1 - 0.0021 17.9 2.8 1.3 8.9 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.4 ETO05082.1 - 0.015 15.2 0.1 7.9 6.4 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETO05082.1 - 0.037 13.8 1.8 8.6 6.4 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TH1 PF04858.8 ETO05083.1 - 0.19 9.8 5.3 0.45 8.6 0.0 3.0 3 1 0 3 3 3 0 TH1 protein Curto_V2 PF07325.6 ETO05083.1 - 0.39 10.3 4.1 0.19 11.4 0.5 2.2 2 0 0 2 2 2 0 Curtovirus V2 protein HATPase_c PF02518.21 ETO05086.1 - 0.014 15.1 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SNAPc19 PF15497.1 ETO05089.1 - 0.033 14.3 1.0 0.033 14.3 0.7 1.8 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Rgp1 PF08737.5 ETO05089.1 - 0.25 10.3 4.7 0.3 10.1 3.3 1.0 1 0 0 1 1 1 0 Rgp1 DUF2072 PF09845.4 ETO05089.1 - 0.27 11.1 2.9 0.14 12.0 0.3 1.7 1 1 1 2 2 2 0 Zn-ribbon containing protein (DUF2072) FISNA PF14484.1 ETO05090.1 - 0.29 11.1 6.8 0.064 13.2 2.5 1.6 2 0 0 2 2 2 0 Fish-specific NACHT associated domain DUF4363 PF14276.1 ETO05090.1 - 0.4 10.4 4.1 0.54 9.9 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) PV_NSP1 PF12433.3 ETO05090.1 - 0.7 10.0 9.2 0.63 10.1 2.0 2.4 2 1 0 2 2 2 0 Parvovirus non-structural protein 1 Pex24p PF06398.6 ETO05090.1 - 1.4 7.6 4.9 1.4 7.6 3.4 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Protocadherin PF08374.6 ETO05090.1 - 1.5 8.4 7.6 0.5 9.9 3.6 1.4 1 1 0 1 1 1 0 Protocadherin Leu_Phe_trans PF03588.9 ETO05094.1 - 2.7e-21 75.4 0.6 1.6e-13 50.1 0.0 2.7 3 0 0 3 3 3 2 Leucyl/phenylalanyl-tRNA protein transferase Cadherin PF00028.12 ETO05094.1 - 0.071 13.3 1.3 0.19 12.0 0.9 1.7 1 0 0 1 1 1 0 Cadherin domain DDHD PF02862.12 ETO05094.1 - 0.31 10.7 4.9 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 DDHD domain Mem_trans PF03547.13 ETO05094.1 - 9.3 4.4 6.2 9.7 4.3 2.1 2.0 2 0 0 2 2 2 0 Membrane transport protein Clathrin PF00637.15 ETO05095.1 - 6.6e-156 512.0 27.4 3.4e-30 104.5 0.3 6.1 6 0 0 6 6 6 6 Region in Clathrin and VPS TPR_14 PF13428.1 ETO05095.1 - 5.8e-05 23.3 5.2 3.3 8.5 0.0 7.1 6 1 1 7 7 7 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.9 ETO05095.1 - 0.00016 20.6 1.2 0.11 11.2 0.0 2.4 2 0 0 2 2 2 2 Coatomer WD associated region TPR_11 PF13414.1 ETO05095.1 - 0.0074 15.9 4.1 0.6 9.8 0.4 4.2 4 0 0 4 4 4 1 TPR repeat Clathrin_H_link PF13838.1 ETO05096.1 - 2.3e-16 59.4 1.6 3.3e-16 58.9 0.2 2.0 2 0 0 2 2 2 1 Clathrin-H-link Clathrin PF00637.15 ETO05096.1 - 3.2e-16 59.2 4.0 2.6e-15 56.2 0.2 3.1 2 1 0 3 3 3 1 Region in Clathrin and VPS Clathrin_propel PF01394.15 ETO05096.1 - 3.1e-07 30.2 0.2 0.13 12.6 0.0 5.0 5 0 0 5 5 5 2 Clathrin propeller repeat FliX PF10768.4 ETO05096.1 - 0.07 13.3 0.3 0.15 12.2 0.2 1.5 1 0 0 1 1 1 0 Class II flagellar assembly regulator NifU PF01106.12 ETO05098.1 - 2.2e-21 75.3 0.0 3.8e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain DUF1338 PF07063.8 ETO05098.1 - 1.5e-10 40.6 0.0 2e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) WD40 PF00400.27 ETO05099.1 - 4e-77 251.5 18.3 2.3e-12 46.2 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO05099.1 - 3e-06 25.6 6.4 0.017 13.3 0.2 4.6 1 1 2 3 3 3 3 Nucleoporin Nup120/160 PD40 PF07676.7 ETO05099.1 - 0.0016 18.0 5.5 28 4.5 0.0 6.0 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 ETO05099.1 - 0.038 12.5 0.2 9.2 4.7 0.0 3.2 1 1 2 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PLD_C PF12357.3 ETO05099.1 - 0.082 12.4 0.1 18 4.9 0.0 3.6 2 2 1 4 4 4 0 Phospholipase D C terminal NtA PF03146.10 ETO05099.1 - 0.14 11.7 0.8 0.58 9.8 0.0 2.4 3 1 1 4 4 4 0 Agrin NtA domain DUF1914 PF08932.5 ETO05099.1 - 0.23 11.4 2.9 0.89 9.6 0.1 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1914) DUF788 PF05620.6 ETO05100.1 - 0.039 13.8 5.0 0.23 11.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF788) AF1Q PF15017.1 ETO05100.1 - 0.69 9.8 5.7 1 9.3 3.1 1.9 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator Ribosomal_60s PF00428.14 ETO05100.1 - 0.9 9.9 6.1 5.9 7.3 2.9 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF2363 PF10155.4 ETO05101.1 - 0.013 15.4 3.7 0.015 15.2 2.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2363) WD40 PF00400.27 ETO05103.1 - 8.1e-46 152.3 16.6 2.6e-12 46.1 0.0 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO05103.1 - 2.2e-09 35.9 1.4 0.035 12.2 0.0 4.0 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Zip PF02535.17 ETO05105.1 - 0.042 12.8 5.3 0.075 12.0 3.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter HSP70 PF00012.15 ETO05106.1 - 0.0034 15.3 0.0 0.0036 15.3 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein DUF2267 PF10025.4 ETO05107.1 - 0.0045 17.0 0.5 0.005 16.8 0.4 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2267) Syntaxin-18_N PF10496.4 ETO05107.1 - 0.12 12.2 2.1 0.17 11.7 1.5 1.4 1 1 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus AAA_32 PF13654.1 ETO05107.1 - 0.14 10.7 4.8 0.16 10.5 3.3 1.0 1 0 0 1 1 1 0 AAA domain Red1 PF07964.6 ETO05107.1 - 0.16 10.1 6.9 0.18 9.8 4.8 1.0 1 0 0 1 1 1 0 Rec10 / Red1 DUF2939 PF11159.3 ETO05107.1 - 0.21 11.8 1.0 6.8 6.9 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) DUF445 PF04286.7 ETO05107.1 - 0.39 10.1 3.2 0.42 10.0 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DNA_primase_lrg PF04104.9 ETO05107.1 - 0.41 9.8 3.4 0.48 9.6 2.4 1.1 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit YlqD PF11068.3 ETO05107.1 - 0.43 10.6 5.7 0.59 10.1 4.0 1.2 1 0 0 1 1 1 0 YlqD protein RapA_C PF12137.3 ETO05107.1 - 0.74 8.5 4.9 0.8 8.4 3.4 1.0 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal Kinetocho_Slk19 PF12709.2 ETO05107.1 - 1.1 9.4 9.8 1.6 8.8 6.8 1.3 1 0 0 1 1 1 0 Central kinetochore-associated TPD52 PF04201.10 ETO05107.1 - 3.3 7.4 11.1 1.1 8.9 2.2 2.1 1 1 1 2 2 2 0 Tumour protein D52 family PRP1_N PF06424.7 ETO05107.1 - 3.3 8.0 8.9 4.5 7.5 6.1 1.2 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal Asp-B-Hydro_N PF05279.6 ETO05107.1 - 8.5 6.1 9.4 9.7 5.9 6.5 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF3854 PF12965.2 ETO05108.1 - 0.053 13.1 0.6 0.09 12.4 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) TPR_8 PF13181.1 ETO05109.1 - 0.0081 15.8 0.3 0.025 14.3 0.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_20 PF14561.1 ETO05109.1 - 0.12 12.5 1.1 2.2 8.4 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Raftlin PF15250.1 ETO05109.1 - 0.23 9.9 6.0 0.27 9.7 4.1 1.3 1 0 0 1 1 1 0 Raftlin CENP-T PF15511.1 ETO05109.1 - 1 8.5 11.9 1.4 8.0 8.3 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CobT PF06213.7 ETO05109.1 - 1.8 7.6 21.1 2.6 7.0 14.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Hid1 PF12722.2 ETO05109.1 - 4.8 4.7 17.7 5.7 4.4 12.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.9 ETO05109.1 - 4.8 5.0 19.3 6.1 4.7 13.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2076 PF09849.4 ETO05109.1 - 8.3 6.3 18.8 16 5.4 13.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) TLD PF07534.11 ETO05110.1 - 6.1e-12 45.7 0.5 4.5e-11 42.8 0.1 2.7 2 0 0 2 2 2 1 TLD Fib_alpha PF08702.5 ETO05111.1 - 0.039 14.0 3.3 0.055 13.5 2.3 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family WD40 PF00400.27 ETO05112.1 - 2e-06 27.4 0.3 2e-06 27.4 0.2 2.2 2 1 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO05112.1 - 0.11 10.6 0.0 0.11 10.6 0.0 1.0 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Toxin_21 PF08091.6 ETO05112.1 - 1.7 8.3 7.6 3.5 7.3 1.5 2.9 3 0 0 3 3 3 0 Spider insecticidal peptide G-alpha PF00503.15 ETO05113.1 - 0.0066 15.1 0.3 0.0066 15.1 0.2 2.0 2 0 0 2 2 2 1 G-protein alpha subunit DUF2666 PF10869.3 ETO05113.1 - 0.03 14.3 4.3 0.04 13.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) ELH PF02323.10 ETO05114.1 - 0.016 14.3 0.1 0.027 13.6 0.1 1.3 1 0 0 1 1 1 0 Egg-laying hormone precursor WD40 PF00400.27 ETO05115.1 - 1.8e-19 68.7 7.6 5.6e-12 45.0 0.9 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO05115.1 - 0.00033 18.9 0.2 0.00036 18.7 0.1 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 YsaB PF13983.1 ETO05115.1 - 0.43 10.7 1.7 0.7 10.1 0.5 1.9 2 1 0 2 2 2 0 YsaB-like lipoprotein WD40 PF00400.27 ETO05116.1 - 6.7e-69 225.5 23.8 1.7e-13 49.8 0.1 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO05116.1 - 3.8e-13 48.4 3.1 0.00077 17.7 0.2 4.2 1 1 3 4 4 4 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO05116.1 - 5.2e-05 22.8 0.5 0.017 14.5 0.1 2.3 1 1 1 2 2 2 2 PQQ-like domain PD40 PF07676.7 ETO05116.1 - 8.7e-05 22.0 6.5 14 5.4 0.0 5.8 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO05116.1 - 9.9e-05 20.7 3.0 0.14 10.3 0.1 3.4 1 1 3 4 4 4 2 Cytochrome D1 heme domain DPPIV_N PF00930.16 ETO05116.1 - 0.00054 18.6 0.2 1.1 7.7 0.0 4.1 1 1 2 4 4 4 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nucleoporin_N PF08801.6 ETO05116.1 - 0.00057 18.7 6.7 0.063 12.0 0.8 4.1 1 1 3 4 4 4 1 Nup133 N terminal like SoxZ PF08770.6 ETO05116.1 - 0.03 13.7 0.1 3.1 7.2 0.0 3.0 3 0 0 3 3 3 0 Sulphur oxidation protein SoxZ PQQ PF01011.16 ETO05116.1 - 0.034 13.6 0.0 1.6 8.4 0.0 3.6 4 1 1 5 5 5 0 PQQ enzyme repeat PQQ_3 PF13570.1 ETO05116.1 - 0.12 12.6 0.0 3 8.2 0.0 3.0 3 0 0 3 3 3 0 PQQ-like domain Proteasome_A_N PF10584.4 ETO05116.1 - 0.83 9.0 7.8 17 4.8 0.0 4.6 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature PPR_2 PF13041.1 ETO05117.1 - 1.9e-17 62.9 7.3 3.1e-09 36.6 0.1 5.0 3 1 2 5 5 5 5 PPR repeat family PPR_3 PF13812.1 ETO05117.1 - 1.2e-15 56.3 0.0 1.4e-06 28.0 0.0 5.6 6 0 0 6 6 6 3 Pentatricopeptide repeat domain PPR PF01535.15 ETO05117.1 - 1.3e-14 53.0 5.7 1.4e-05 24.7 0.1 5.0 5 0 0 5 5 5 3 PPR repeat PPR_1 PF12854.2 ETO05117.1 - 4.2e-08 32.5 4.1 8.9e-05 21.8 0.0 4.5 5 0 0 5 5 5 2 PPR repeat F-box-like PF12937.2 ETO05118.1 - 2e-06 27.3 0.9 5.8e-06 25.9 0.6 1.8 1 0 0 1 1 1 1 F-box-like Csm1 PF12539.3 ETO05118.1 - 0.09 13.2 0.1 0.36 11.3 0.0 2.0 2 0 0 2 2 2 0 Chromosome segregation protein Csm1/Pcs1 FA_hydroxylase PF04116.8 ETO05119.1 - 0.14 12.6 2.2 0.2 12.0 1.5 1.2 1 0 0 1 1 1 0 Fatty acid hydroxylase superfamily WD40 PF00400.27 ETO05120.1 - 2.7e-49 163.3 28.6 6.6e-11 41.6 0.3 6.8 7 1 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO05120.1 - 3.1e-08 32.2 3.5 0.0063 14.7 0.6 5.3 2 2 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO05120.1 - 0.1 11.3 9.7 0.81 8.3 0.1 3.9 1 1 2 3 3 3 0 Nup133 N terminal like Kelch_6 PF13964.1 ETO05121.1 - 2.9e-05 24.0 0.6 0.00019 21.4 0.0 2.4 1 1 1 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO05121.1 - 0.015 15.4 0.0 0.041 14.0 0.0 1.8 1 0 0 1 1 1 0 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO05121.1 - 0.026 14.0 1.5 0.037 13.5 0.1 2.0 2 0 0 2 2 2 0 Kelch motif Kelch_5 PF13854.1 ETO05121.1 - 0.093 12.7 0.4 0.26 11.2 0.1 1.9 2 0 0 2 2 2 0 Kelch motif DUF4149 PF13664.1 ETO05122.1 - 0.052 13.6 10.1 0.31 11.1 0.2 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4149) Herpes_LMP1 PF05297.6 ETO05122.1 - 1.6 7.5 5.2 2 7.2 3.6 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF1743 PF08489.6 ETO05124.1 - 0.0038 16.9 0.0 0.012 15.3 0.0 1.8 1 1 1 2 2 2 2 Domain of unknown function (DUF1743) WD40 PF00400.27 ETO05125.1 - 1.4e-59 195.9 19.3 2.5e-10 39.8 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO05125.1 - 3.9e-12 45.0 4.1 0.00034 18.9 0.0 5.5 1 1 4 6 6 6 5 Nucleoporin Nup120/160 HAD PF12710.2 ETO05125.1 - 0.063 13.4 2.7 6.1 6.9 0.1 3.0 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Bul1_N PF04425.7 ETO05126.1 - 0.013 14.0 4.3 0.015 13.8 3.0 1.1 1 0 0 1 1 1 0 Bul1 N terminus FimP PF09766.4 ETO05126.1 - 0.031 13.3 7.8 0.036 13.1 5.4 1.1 1 0 0 1 1 1 0 Fms-interacting protein DUF3464 PF11947.3 ETO05126.1 - 0.076 12.4 1.5 0.1 12.0 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) BRF1 PF07741.8 ETO05126.1 - 0.095 12.9 12.7 0.15 12.3 8.8 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain CDC45 PF02724.9 ETO05126.1 - 0.097 10.6 11.1 0.1 10.6 7.7 1.0 1 0 0 1 1 1 0 CDC45-like protein SID-1_RNA_chan PF13965.1 ETO05126.1 - 0.14 10.3 1.9 0.16 10.0 1.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Spore_coat_CotO PF14153.1 ETO05126.1 - 0.31 10.4 10.1 0.38 10.1 7.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO PP_M1 PF03012.9 ETO05126.1 - 0.41 9.9 8.7 0.5 9.6 6.0 1.1 1 0 0 1 1 1 0 Phosphoprotein Daxx PF03344.10 ETO05126.1 - 0.47 8.8 13.5 0.5 8.7 9.3 1.0 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 ETO05126.1 - 0.52 9.6 16.7 0.61 9.4 11.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NPR3 PF03666.8 ETO05126.1 - 0.62 8.5 6.9 0.72 8.3 4.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2201_N PF13203.1 ETO05126.1 - 0.69 9.0 5.6 0.76 8.8 3.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Tom37_C PF11801.3 ETO05126.1 - 0.93 9.3 5.4 1.1 9.1 3.7 1.1 1 0 0 1 1 1 0 Tom37 C-terminal domain Paramyxo_ncap PF00973.14 ETO05126.1 - 1.4 7.5 6.2 1.7 7.2 4.3 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DDHD PF02862.12 ETO05126.1 - 3.7 7.2 8.1 4.2 7.0 5.6 1.1 1 0 0 1 1 1 0 DDHD domain Rota_VP2 PF05087.7 ETO05126.1 - 4.1 5.1 12.8 4.8 4.9 8.9 1.0 1 0 0 1 1 1 0 Rotavirus VP2 protein RNA_polI_A34 PF08208.6 ETO05126.1 - 5 6.7 16.7 6.3 6.4 11.6 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 zf-MIZ PF02891.15 ETO05128.1 - 4.2e-05 22.9 1.0 8.2e-05 22.0 0.2 1.9 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger DUF2207 PF09972.4 ETO05128.1 - 0.0028 16.3 4.3 0.0036 15.9 3.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF3931 PF13082.1 ETO05128.1 - 0.079 12.8 0.2 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3931) DUF4191 PF13829.1 ETO05128.1 - 1.7 7.6 3.4 2.5 7.1 1.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) MCM PF00493.18 ETO05129.1 - 0.0011 17.8 0.0 0.0021 16.9 0.0 1.5 1 0 0 1 1 1 1 MCM2/3/5 family Phage_TAC PF06222.6 ETO05129.1 - 0.036 13.6 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone DUF4538 PF15061.1 ETO05130.1 - 0.032 13.5 0.2 0.32 10.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) FAD_binding_4 PF01565.18 ETO05132.1 - 0.011 15.1 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain MIP-T3 PF10243.4 ETO05134.1 - 0.035 12.5 30.0 0.044 12.2 20.8 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 WD40 PF00400.27 ETO05135.1 - 2e-43 144.7 17.8 8e-13 47.7 0.3 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO05135.1 - 0.0035 17.0 5.6 0.51 10.0 0.1 3.9 1 1 4 5 5 5 2 Eukaryotic translation initiation factor eIF2A Imm46 PF15585.1 ETO05135.1 - 0.01 15.9 0.1 1.9 8.5 0.0 2.4 2 0 0 2 2 2 2 Immunity protein 46 BBS2_Mid PF14783.1 ETO05135.1 - 0.012 15.3 2.7 2.5 7.8 0.1 4.4 2 2 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Ribosomal_S27e PF01667.12 ETO05135.1 - 0.051 13.1 0.2 0.14 11.7 0.1 1.7 1 0 0 1 1 1 0 Ribosomal protein S27 WD40 PF00400.27 ETO05136.1 - 3.9e-16 58.2 0.3 5e-07 29.3 0.1 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF4248 PF14053.1 ETO05136.1 - 0.083 12.4 0.1 1.2 8.7 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4248) IER PF05760.7 ETO05137.1 - 0.062 13.2 0.8 0.084 12.7 0.6 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) vATP-synt_E PF01991.13 ETO05138.1 - 0.024 13.9 1.2 0.029 13.6 0.8 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit ASFV_L11L PF05293.6 ETO05140.1 - 0.11 12.5 3.0 0.18 11.9 2.1 1.4 1 0 0 1 1 1 0 African swine fever virus (ASFV) L11L protein STE2 PF02116.10 ETO05140.1 - 0.26 10.2 2.6 0.29 10.1 1.8 1.0 1 0 0 1 1 1 0 Fungal pheromone mating factor STE2 GPCR ICE2 PF08426.5 ETO05141.1 - 1.1 7.7 4.5 0.61 8.6 1.1 1.8 2 0 0 2 2 2 0 ICE2 Rad60-SLD PF11976.3 ETO05142.1 - 7.7e-07 28.7 0.1 7.7e-07 28.7 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like TRAP-gamma PF07074.7 ETO05143.1 - 0.0039 16.7 1.8 0.0045 16.5 1.2 1.1 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) PH PF00169.24 ETO05145.1 - 2.3e-09 37.3 0.6 4.6e-09 36.4 0.4 1.5 1 0 0 1 1 1 1 PH domain PH_3 PF14593.1 ETO05145.1 - 6.5e-08 32.4 0.6 4.3e-07 29.7 0.4 2.0 1 1 0 1 1 1 1 PH domain PH_11 PF15413.1 ETO05145.1 - 1.6e-05 25.0 2.6 1.6e-05 25.0 1.8 2.3 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 ETO05145.1 - 0.00067 19.6 0.4 0.0056 16.7 0.3 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain Mcp5_PH PF12814.2 ETO05145.1 - 0.0053 16.6 0.2 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH_7 PF15408.1 ETO05145.1 - 0.016 15.1 0.1 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain PY_rept_46 PF09689.5 ETO05145.1 - 0.22 11.9 3.0 8 6.8 0.4 2.5 2 0 0 2 2 2 0 Plasmodium yoelii repeat (PY_rept_46) DUF806 PF05657.6 ETO05146.1 - 0.029 14.3 0.4 0.045 13.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF806) RcsC PF09456.5 ETO05146.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 RcsC Alpha-Beta-Loop (ABL) FNIP_N PF14636.1 ETO05146.1 - 0.4 11.1 4.6 0.25 11.8 1.7 1.6 1 1 1 2 2 2 0 Folliculin-interacting protein N-terminus Tubulin PF00091.20 ETO05148.1 - 8.8e-52 176.0 0.0 1.5e-51 175.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO05148.1 - 3.5e-49 166.0 0.1 5.9e-49 165.2 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 ETO05148.1 - 6.3e-05 23.0 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain VP_N-CPKC PF11475.3 ETO05149.1 - 5.5 6.6 11.2 0.19 11.2 0.6 2.8 3 0 0 3 3 3 0 Virion protein N terminal domain DUF2553 PF10830.3 ETO05151.1 - 0.046 14.2 1.5 0.05 14.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2553) PDGF PF00341.12 ETO05151.1 - 0.11 12.6 1.9 0.16 12.0 1.3 1.5 1 1 0 1 1 1 0 PDGF/VEGF domain F-box PF00646.28 ETO05154.1 - 0.045 13.4 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 F-box domain DUF1687 PF07955.6 ETO05157.1 - 0.005 16.8 0.1 0.048 13.6 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1687) AIG1 PF04548.11 ETO05157.1 - 0.073 12.1 1.9 0.075 12.1 0.4 1.6 1 1 1 2 2 2 0 AIG1 family TPP1 PF10341.4 ETO05158.1 - 0.095 12.6 1.4 0.77 9.7 0.5 2.2 1 1 1 2 2 2 0 Shelterin complex subunit, TPP1/ACD HTH_16 PF12645.2 ETO05158.1 - 0.13 12.2 0.4 0.33 10.9 0.3 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Peptidase_S3 PF00944.14 ETO05161.1 - 0.054 12.9 0.1 0.1 11.9 0.0 1.5 1 1 1 2 2 2 0 Alphavirus core protein Surfac_D-trimer PF09006.6 ETO05162.1 - 0.1 12.3 0.2 0.2 11.4 0.2 1.5 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation 7tm_6 PF02949.15 ETO05163.1 - 0.031 13.1 2.3 0.049 12.4 1.6 1.3 1 1 0 1 1 1 0 7tm Odorant receptor Sec62 PF03839.11 ETO05163.1 - 0.13 11.6 5.6 0.16 11.3 3.9 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 FH2 PF02181.18 ETO05164.1 - 3.1e-11 42.7 5.3 3.1e-11 42.7 3.7 2.4 1 1 1 2 2 2 1 Formin Homology 2 Domain JmjN PF02375.12 ETO05164.1 - 0.012 15.1 0.2 0.047 13.2 0.0 2.0 2 0 0 2 2 2 0 jmjN domain DUF4298 PF14131.1 ETO05164.1 - 1.4 8.8 6.3 0.28 11.1 0.4 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4298) Lectin_N PF03954.9 ETO05164.1 - 2.9 7.2 4.6 17 4.8 0.9 2.3 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Menin PF05053.8 ETO05165.1 - 0.035 12.2 8.1 0.045 11.9 5.6 1.1 1 0 0 1 1 1 0 Menin CobT PF06213.7 ETO05165.1 - 0.036 13.2 5.2 0.046 12.8 3.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT POX PF07526.6 ETO05165.1 - 0.15 12.3 1.4 0.23 11.7 1.0 1.4 1 0 0 1 1 1 0 Associated with HOX Apc15p PF05841.6 ETO05165.1 - 0.22 12.2 10.8 0.36 11.5 7.5 1.4 1 0 0 1 1 1 0 Apc15p protein DUF3437 PF11919.3 ETO05166.1 - 2.5e-32 110.4 0.0 1.6e-31 107.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT PF02985.17 ETO05166.1 - 0.073 13.1 0.1 9.9 6.5 0.0 3.0 3 0 0 3 3 3 0 HEAT repeat CLASP_N PF12348.3 ETO05166.1 - 0.11 11.8 3.0 1 8.6 2.1 2.2 1 1 0 1 1 1 0 CLASP N terminal Sds3 PF08598.6 ETO05167.1 - 0.0035 16.8 6.4 0.0051 16.3 4.5 1.3 1 0 0 1 1 1 1 Sds3-like Toxin_21 PF08091.6 ETO05167.1 - 0.006 16.2 1.8 0.0089 15.7 1.2 1.2 1 0 0 1 1 1 1 Spider insecticidal peptide IncA PF04156.9 ETO05167.1 - 0.02 14.5 4.3 0.021 14.4 3.0 1.2 1 0 0 1 1 1 0 IncA protein AAA_32 PF13654.1 ETO05167.1 - 0.024 13.3 4.1 0.029 13.0 2.8 1.1 1 0 0 1 1 1 0 AAA domain Fucose_iso_N2 PF07882.7 ETO05167.1 - 0.032 13.9 0.6 0.042 13.5 0.4 1.2 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain Rieske PF00355.21 ETO05168.1 - 1.2e-07 31.2 0.0 1.8e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DUF973 PF06157.6 ETO05168.1 - 0.032 13.2 0.0 0.041 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) G-alpha PF00503.15 ETO05169.1 - 6.2e-52 176.5 4.7 1.4e-50 172.0 0.6 2.5 2 1 0 2 2 2 2 G-protein alpha subunit Arf PF00025.16 ETO05169.1 - 6.9e-06 25.4 0.1 5.4e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family SnoaL_2 PF12680.2 ETO05170.1 - 0.012 15.9 0.0 0.65 10.4 0.0 2.4 2 0 0 2 2 2 0 SnoaL-like domain PUB PF09409.5 ETO05171.1 - 0.0039 16.9 0.0 0.0055 16.4 0.0 1.3 1 0 0 1 1 1 1 PUB domain zf-RanBP PF00641.13 ETO05172.1 - 0.017 14.2 0.6 0.031 13.3 0.4 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others DUF3753 PF12575.3 ETO05172.1 - 0.98 9.2 4.5 1.4 8.8 3.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3753) ETRAMP PF09716.5 ETO05172.1 - 1.5 8.7 4.4 1.5 8.8 2.5 1.3 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) zf-CCHC_3 PF13917.1 ETO05173.1 - 1.5e-06 27.7 0.9 1.5e-06 27.7 0.6 2.2 2 0 0 2 2 2 1 Zinc knuckle Mitofilin PF09731.4 ETO05173.1 - 0.6 8.7 36.7 0.77 8.3 25.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Totivirus_coat PF05518.6 ETO05173.1 - 0.92 7.2 7.7 1.2 6.9 5.3 1.1 1 0 0 1 1 1 0 Totivirus coat protein DUF936 PF06075.7 ETO05173.1 - 2 7.2 36.7 2.6 6.8 25.5 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DUF4131 PF13567.1 ETO05174.1 - 0.00028 20.3 0.1 0.00046 19.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) ABC2_membrane_5 PF13346.1 ETO05174.1 - 0.0032 16.7 5.4 0.0058 15.9 3.7 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein Latrotoxin_C PF15658.1 ETO05174.1 - 0.033 14.0 5.0 0.027 14.2 2.5 1.6 2 0 0 2 2 2 0 Latrotoxin C-terminal domain Exonuc_VII_L PF02601.10 ETO05174.1 - 0.047 12.8 6.1 0.063 12.4 4.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit AbiH PF14253.1 ETO05174.1 - 0.62 9.6 5.8 0.96 8.9 4.0 1.2 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH DUF445 PF04286.7 ETO05174.1 - 3.6 7.0 8.4 5.9 6.3 5.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) AAA_13 PF13166.1 ETO05176.1 - 0.35 9.2 5.5 0.38 9.1 3.8 1.0 1 0 0 1 1 1 0 AAA domain Tom22 PF04281.8 ETO05176.1 - 1.1 8.8 9.1 1.2 8.6 6.3 1.1 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 WD40 PF00400.27 ETO05177.1 - 5.7e-39 130.6 10.7 1.9e-11 43.3 0.2 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO05177.1 - 0.002 16.9 0.1 0.076 11.7 0.1 2.1 2 0 0 2 2 2 2 Nup133 N terminal like rve PF00665.21 ETO05178.1 - 1.2e-28 99.5 0.0 1.8e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 ETO05178.1 - 0.00012 21.4 0.0 0.00034 20.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 ETO05178.1 - 0.0046 16.9 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 DDE domain NACHT PF05729.7 ETO05179.1 - 1.5e-11 44.2 0.1 2.1e-10 40.5 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 ETO05179.1 - 4.1e-05 23.7 0.0 0.00018 21.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETO05179.1 - 8.8e-05 22.8 0.0 8.8e-05 22.8 0.0 4.1 5 1 0 5 5 5 1 AAA domain AAA_17 PF13207.1 ETO05179.1 - 0.001 19.8 0.3 0.0071 17.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 ETO05179.1 - 0.035 13.8 0.0 8.7 6.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) WD40 PF00400.27 ETO05180.1 - 5.1e-174 558.7 47.9 4e-15 55.0 0.2 14.2 14 0 0 14 14 14 14 WD domain, G-beta repeat PD40 PF07676.7 ETO05180.1 - 8.5e-08 31.7 21.9 1.4 8.6 0.1 10.8 11 0 0 11 11 11 1 WD40-like Beta Propeller Repeat DUF727 PF05303.7 ETO05180.1 - 1.7e-07 30.9 3.0 8.4 6.2 0.0 7.5 6 3 1 7 7 7 2 Protein of unknown function (DUF727) Cytochrom_D1 PF02239.11 ETO05180.1 - 2.4e-06 26.1 4.6 2 6.5 0.0 5.4 3 2 1 5 5 5 4 Cytochrome D1 heme domain TolB_N PF04052.8 ETO05180.1 - 9e-06 25.7 0.1 51 4.0 0.0 8.1 10 0 0 10 10 10 0 TolB amino-terminal domain PQQ_2 PF13360.1 ETO05180.1 - 1.8e-05 24.3 4.9 0.073 12.5 1.0 5.2 2 2 1 3 3 3 1 PQQ-like domain DUF1258 PF06869.7 ETO05180.1 - 2e-05 23.8 5.8 14 4.6 0.0 7.0 4 2 3 8 8 8 0 Protein of unknown function (DUF1258) Pentapeptide_3 PF13576.1 ETO05180.1 - 9.9e-05 22.1 1.2 0.00091 19.0 0.8 2.7 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETO05180.1 - 0.00019 20.5 1.7 0.00044 19.4 1.1 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Cofilin_ADF PF00241.15 ETO05180.1 - 0.00084 19.2 1.3 10 5.9 0.0 6.2 5 3 2 8 8 7 1 Cofilin/tropomyosin-type actin-binding protein USP7_C2 PF14533.1 ETO05180.1 - 0.0011 18.4 0.1 7.5 5.9 0.0 5.7 4 3 4 8 8 8 1 Ubiquitin-specific protease C-terminal Pentapeptide_4 PF13599.1 ETO05180.1 - 0.0014 18.4 0.2 0.0047 16.7 0.1 1.9 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) TnpW PF14202.1 ETO05180.1 - 0.054 13.1 2.7 42 3.8 0.1 4.8 4 0 0 4 4 4 0 Transposon-encoded protein TnpW Metallophos PF00149.23 ETO05181.1 - 6.9e-17 61.4 0.0 9.4e-17 61.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Kelch_5 PF13854.1 ETO05183.1 - 0.0063 16.4 0.2 0.66 9.9 0.0 2.4 1 1 1 2 2 2 2 Kelch motif NACHT PF05729.7 ETO05184.1 - 0.011 15.4 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 0 NACHT domain Tctex-1 PF03645.8 ETO05184.1 - 0.094 12.5 0.6 2.3 8.0 0.0 2.1 2 0 0 2 2 2 0 Tctex-1 family HECT PF00632.20 ETO05185.1 - 8.1e-54 182.8 0.1 1e-53 182.5 0.1 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PMSR PF01625.16 ETO05187.1 - 0.0022 17.8 1.0 0.017 14.9 0.0 2.7 2 0 0 2 2 2 1 Peptide methionine sulfoxide reductase DUF211 PF02680.9 ETO05187.1 - 0.028 14.1 0.2 16 5.4 0.0 3.0 2 0 0 2 2 2 0 Uncharacterized ArCR, COG1888 PilJ PF13675.1 ETO05187.1 - 0.88 9.9 5.2 0.85 9.9 0.1 3.5 3 1 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term PB1-F2 PF11986.3 ETO05188.1 - 0.2 11.7 1.2 0.23 11.5 0.1 1.8 2 0 0 2 2 2 0 Influenza A Proapoptotic protein AAA PF00004.24 ETO05189.1 - 2.6e-09 37.3 7.2 0.0072 16.5 0.0 4.2 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETO05189.1 - 3.5e-07 30.0 3.0 0.0017 18.1 0.6 4.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETO05189.1 - 1.3e-06 28.5 2.7 0.0091 16.1 0.7 3.4 2 2 0 2 2 2 2 AAA domain ABC_tran PF00005.22 ETO05189.1 - 4.7e-06 26.9 1.5 2.2e-05 24.7 0.5 2.4 2 0 0 2 2 2 1 ABC transporter DUF258 PF03193.11 ETO05189.1 - 2.1e-05 23.7 0.0 5.6e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 ETO05189.1 - 0.00025 21.1 0.0 0.05 13.5 0.0 3.2 2 1 0 2 2 2 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 ETO05189.1 - 0.0031 17.5 0.0 0.072 13.1 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain PduV-EutP PF10662.4 ETO05189.1 - 0.0032 16.9 0.1 0.022 14.2 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 ETO05189.1 - 0.0049 17.3 2.4 0.012 16.0 0.4 2.8 3 1 0 3 3 2 1 Miro-like protein DUF815 PF05673.8 ETO05189.1 - 0.0058 15.5 0.0 0.0058 15.5 0.0 2.1 2 0 0 2 2 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.17 ETO05189.1 - 0.0076 16.4 0.7 0.28 11.3 0.0 3.5 4 0 0 4 4 3 1 RNA helicase AAA_14 PF13173.1 ETO05189.1 - 0.0099 15.7 10.0 12 5.7 4.0 4.2 3 1 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 ETO05189.1 - 0.026 14.2 19.2 0.064 12.9 9.6 3.7 3 1 0 3 3 3 0 Archaeal ATPase IstB_IS21 PF01695.12 ETO05189.1 - 0.029 13.7 0.1 3.5 6.9 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein Sigma54_activat PF00158.21 ETO05189.1 - 0.047 13.1 0.2 1.2 8.6 0.0 3.1 4 0 0 4 4 2 0 Sigma-54 interaction domain AAA_3 PF07726.6 ETO05189.1 - 0.047 13.2 0.0 7.8 6.1 0.0 3.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 ETO05189.1 - 0.066 12.8 0.2 0.42 10.2 0.0 2.4 3 0 0 3 3 2 0 NACHT domain AAA_28 PF13521.1 ETO05189.1 - 0.067 13.1 9.0 0.28 11.1 0.4 3.9 3 1 1 4 4 4 0 AAA domain Mg_chelatase PF01078.16 ETO05189.1 - 0.081 12.0 0.2 12 4.9 0.0 3.3 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI LMBR1 PF04791.11 ETO05189.1 - 0.11 11.0 2.4 0.16 10.4 1.6 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein AAA_18 PF13238.1 ETO05189.1 - 0.11 12.8 14.3 0.41 10.9 7.5 3.5 3 1 0 3 3 2 0 AAA domain Viral_helicase1 PF01443.13 ETO05189.1 - 0.29 10.6 1.8 3.7 7.0 0.0 2.7 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.1 ETO05189.1 - 0.29 11.9 9.8 0.18 12.6 2.5 3.9 4 1 0 4 4 1 0 AAA domain DUF2252 PF10009.4 ETO05189.1 - 0.85 8.4 7.9 1.2 7.9 2.9 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2252) MCM PF00493.18 ETO05189.1 - 1.6 7.4 9.3 0.37 9.5 0.0 3.2 3 0 0 3 3 2 0 MCM2/3/5 family NHS PF15273.1 ETO05189.1 - 7.4 5.0 6.2 10 4.5 4.3 1.1 1 0 0 1 1 1 0 NHS-like ubiquitin PF00240.18 ETO05191.1 - 6.7e-53 175.9 4.3 1e-29 101.7 0.3 2.3 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 ETO05191.1 - 3.3e-29 100.3 1.3 5.7e-15 54.7 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 ETO05191.1 - 2.2e-11 43.8 0.4 0.00013 22.1 0.0 2.9 1 1 1 2 2 2 2 Ubiquitin-like domain DUF2407 PF10302.4 ETO05191.1 - 6.1e-06 26.3 0.1 0.1 12.8 0.0 2.5 1 1 0 2 2 2 2 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 ETO05191.1 - 2e-05 24.4 0.2 0.092 12.6 0.0 2.5 2 0 0 2 2 2 2 GLUT4 regulating protein TUG USP7_C2 PF14533.1 ETO05191.1 - 3.1e-05 23.5 0.5 0.0021 17.5 0.3 2.4 1 1 0 1 1 1 1 Ubiquitin-specific protease C-terminal Rad60-SLD_2 PF13881.1 ETO05191.1 - 0.0022 17.8 4.7 0.36 10.7 0.0 3.4 2 1 1 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like eRF1_1 PF03463.10 ETO05191.1 - 0.0051 16.3 0.2 9.3 5.8 0.0 3.6 1 1 3 4 4 4 1 eRF1 domain 1 Telomere_Sde2 PF13019.1 ETO05191.1 - 0.055 13.1 0.4 6 6.5 0.0 2.7 1 1 2 3 3 3 0 Telomere stability and silencing Pox_A28 PF04584.9 ETO05191.1 - 0.14 12.0 5.2 0.23 11.3 0.9 2.7 2 1 1 3 3 3 0 Poxvirus A28 family Uso1_p115_C PF04871.8 ETO05191.1 - 3.3 7.6 5.4 1.3 8.9 1.5 1.8 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Neur_chan_memb PF02932.11 ETO05192.1 - 4.1 7.2 9.4 6.3 6.6 6.5 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region UBA_4 PF14555.1 ETO05193.1 - 2.7e-12 45.9 0.2 5.7e-12 44.9 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 ETO05193.1 - 2.6e-08 33.8 0.2 1.3e-07 31.5 0.0 2.3 2 0 0 2 2 2 1 UBX domain Coronavirus_5 PF05528.6 ETO05193.1 - 0.032 14.0 0.0 2.7 7.8 0.0 2.6 2 0 0 2 2 2 0 Coronavirus gene 5 protein MMgT PF10270.4 ETO05194.1 - 5.9e-09 36.2 0.1 8.3e-09 35.8 0.1 1.2 1 0 0 1 1 1 1 Membrane magnesium transporter WD40 PF00400.27 ETO05195.1 - 5.7e-06 26.0 3.2 0.067 13.0 0.0 3.6 3 1 0 3 3 3 2 WD domain, G-beta repeat Neurochondrin PF05536.6 ETO05196.1 - 3.6e-07 28.8 4.0 4.9e-05 21.8 0.7 2.1 2 0 0 2 2 2 2 Neurochondrin Atx10homo_assoc PF09759.4 ETO05196.1 - 1.3e-06 28.0 9.0 2e-06 27.4 1.0 2.8 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.8 ETO05196.1 - 0.0032 16.6 6.0 0.011 14.8 0.1 2.1 1 1 1 2 2 2 1 Armadillo-like V-ATPase_H_N PF03224.9 ETO05196.1 - 0.0074 15.4 0.6 0.028 13.5 0.3 1.8 1 1 1 2 2 2 1 V-ATPase subunit H DUF913 PF06025.7 ETO05196.1 - 0.018 13.8 0.3 0.5 9.0 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Ric8 PF10165.4 ETO05196.1 - 0.048 12.4 0.9 0.63 8.8 0.6 2.2 1 1 0 1 1 1 0 Guanine nucleotide exchange factor synembryn N1221 PF07923.8 ETO05196.1 - 0.088 11.6 1.0 6.3 5.5 0.1 2.9 2 1 1 3 3 3 0 N1221-like protein TIMELESS PF04821.9 ETO05196.1 - 0.29 10.3 4.7 0.2 10.8 0.5 2.0 1 1 1 2 2 2 0 Timeless protein DUF3361 PF11841.3 ETO05196.1 - 0.49 10.1 3.0 6.2 6.5 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3361) Arm PF00514.18 ETO05196.1 - 2.7 7.9 11.3 22 5.0 0.1 5.0 4 2 2 6 6 6 0 Armadillo/beta-catenin-like repeat Tubulin_C PF03953.12 ETO05197.1 - 5.8e-23 81.2 0.1 1.3e-22 80.2 0.1 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain WD40 PF00400.27 ETO05198.1 - 4.5e-179 574.7 36.4 6e-14 51.2 0.1 16.3 16 0 0 16 16 16 16 WD domain, G-beta repeat PD40 PF07676.7 ETO05198.1 - 1.3e-08 34.2 25.0 6 6.6 0.2 11.5 12 0 0 12 12 12 3 WD40-like Beta Propeller Repeat Pentapeptide PF00805.17 ETO05198.1 - 1.3e-07 30.6 1.2 2.8e-07 29.6 0.9 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO05198.1 - 1.5e-07 31.1 0.4 4.6e-07 29.5 0.3 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Cytochrom_D1 PF02239.11 ETO05198.1 - 1.9e-06 26.4 3.8 0.26 9.5 0.0 4.8 3 2 1 4 4 4 3 Cytochrome D1 heme domain DUF1258 PF06869.7 ETO05198.1 - 7.5e-06 25.2 6.3 0.46 9.5 0.0 6.2 4 2 2 7 7 7 2 Protein of unknown function (DUF1258) Pentapeptide_3 PF13576.1 ETO05198.1 - 1.1e-05 25.2 0.1 4.1e-05 23.3 0.1 2.1 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) DUF1652 PF07865.6 ETO05198.1 - 0.0002 20.8 0.5 63 3.2 0.0 7.6 8 1 1 9 9 9 0 Protein of unknown function (DUF1652) SUI1 PF01253.17 ETO05199.1 - 2.5e-17 62.4 0.0 5.1e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 SWIB PF02201.13 ETO05199.1 - 0.0033 17.0 0.1 0.0089 15.6 0.0 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain Peptidase_S10 PF00450.17 ETO05200.1 - 4.6e-67 227.0 8.2 5.6e-67 226.7 5.7 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase ATP-synt_A PF00119.15 ETO05200.1 - 0.019 14.4 0.2 0.019 14.4 0.1 2.4 2 1 1 3 3 3 0 ATP synthase A chain Hydrolase_6 PF13344.1 ETO05201.1 - 8.7e-25 86.5 0.1 1.6e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ETO05201.1 - 1.1e-18 66.7 0.0 2.3e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 ETO05201.1 - 4.4e-10 40.3 0.1 9.4e-09 35.9 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 ETO05201.1 - 3.9e-09 36.9 0.2 0.0019 18.4 0.0 3.0 2 1 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Baculo_PEP_N PF04512.7 ETO05201.1 - 0.0036 17.2 0.4 0.0079 16.1 0.2 1.6 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, N terminus HAD PF12710.2 ETO05201.1 - 0.012 15.8 0.0 0.044 13.9 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 ETO05201.1 - 0.046 13.0 0.1 0.75 9.1 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase RGS PF00615.14 ETO05205.1 - 0.017 15.1 3.2 0.18 11.9 0.1 3.1 2 2 0 2 2 2 0 Regulator of G protein signaling domain DUF2684 PF10885.3 ETO05205.1 - 0.05 13.4 0.1 0.14 11.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2684) Ank_4 PF13637.1 ETO05206.1 - 7.6e-05 23.1 0.5 0.00022 21.6 0.3 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO05206.1 - 0.00015 21.9 0.0 0.00034 20.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO05206.1 - 0.017 15.3 1.1 0.39 11.0 0.1 3.3 4 0 0 4 4 4 0 Ankyrin repeats (many copies) DUF3563 PF12086.3 ETO05206.1 - 0.076 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3563) SKG6 PF08693.5 ETO05206.1 - 0.18 11.1 1.2 0.35 10.2 0.8 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Atrophin-1 PF03154.10 ETO05207.1 - 5.2 5.0 11.7 7.7 4.5 8.1 1.1 1 0 0 1 1 1 0 Atrophin-1 family Saccharop_dh PF03435.13 ETO05208.1 - 2.4e-93 313.2 0.0 2.8e-93 312.9 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Aa_trans PF01490.13 ETO05209.1 - 8.6e-05 21.1 3.5 8.6e-05 21.1 2.4 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 ETO05209.1 - 0.00019 20.4 0.7 0.00019 20.4 0.5 1.9 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family DUF4195 PF13836.1 ETO05210.1 - 0.14 11.8 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4195) Bac_small_YrzI PF09501.5 ETO05211.1 - 0.04 13.8 0.1 0.43 10.5 0.0 2.4 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) Pilt PF15453.1 ETO05212.1 - 0.22 11.1 8.7 0.33 10.5 6.0 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Kelch_4 PF13418.1 ETO05213.1 - 1.2e-06 28.1 0.1 0.0032 17.2 0.0 2.6 2 1 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO05213.1 - 0.00016 21.6 2.3 0.0094 16.0 0.1 3.1 1 1 3 4 4 4 1 Kelch motif Kelch_1 PF01344.20 ETO05213.1 - 0.00046 19.6 0.2 0.016 14.7 0.1 2.6 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO05213.1 - 0.0084 16.2 0.1 0.068 13.3 0.0 2.5 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO05213.1 - 0.014 15.3 0.2 0.83 9.6 0.1 2.5 2 0 0 2 2 2 0 Kelch motif Anoctamin PF04547.7 ETO05214.1 - 3.9e-43 147.7 22.6 1.4e-40 139.2 15.6 2.1 1 1 0 1 1 1 1 Calcium-activated chloride channel DUF3816 PF12822.2 ETO05214.1 - 0.0082 16.0 6.9 0.0082 16.0 4.8 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF3816) Zip PF02535.17 ETO05214.1 - 0.089 11.7 1.1 0.8 8.6 0.1 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Kelch_6 PF13964.1 ETO05215.1 - 0.0004 20.4 0.1 0.62 10.3 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 ETO05215.1 - 0.046 13.6 0.0 8.2 6.5 0.0 3.4 3 0 0 3 3 3 0 Kelch motif Hydrolase_3 PF08282.7 ETO05215.1 - 0.11 12.0 5.1 0.049 13.2 1.1 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Fumble PF03630.9 ETO05215.1 - 0.98 8.1 7.5 0.64 8.8 0.6 2.6 3 0 0 3 3 3 0 Fumble His_kinase PF06580.8 ETO05218.1 - 0.049 13.5 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Histidine kinase U-box PF04564.10 ETO05219.1 - 3.3e-12 46.1 0.0 6.5e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 U-box domain Transposase_mut PF00872.13 ETO05221.1 - 0.027 13.0 0.3 0.048 12.2 0.2 1.5 1 0 0 1 1 1 0 Transposase, Mutator family MutS_IV PF05190.13 ETO05221.1 - 0.29 11.3 3.1 1 9.6 2.1 1.9 1 1 0 1 1 1 0 MutS family domain IV zf-primase PF09329.6 ETO05221.1 - 0.42 10.2 5.5 11 5.7 0.1 3.3 3 0 0 3 3 3 0 Primase zinc finger zf-TRAF PF02176.13 ETO05222.1 - 4.4e-06 26.9 2.8 1.8e-05 25.0 1.9 2.1 1 0 0 1 1 1 1 TRAF-type zinc finger Sina PF03145.11 ETO05222.1 - 0.0061 16.2 2.6 0.022 14.4 1.7 2.0 1 1 0 1 1 1 1 Seven in absentia protein family zf-C3HC4_2 PF13923.1 ETO05222.1 - 0.016 15.2 3.7 0.27 11.2 0.1 3.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO05222.1 - 0.12 12.2 3.6 0.42 10.4 0.1 2.9 2 1 0 2 2 2 0 Ring finger domain GP41 PF00517.12 ETO05222.1 - 0.16 11.5 4.2 0.22 11.0 2.9 1.3 1 0 0 1 1 1 0 Retroviral envelope protein WD40 PF00400.27 ETO05223.1 - 3e-10 39.5 6.1 1.2e-08 34.4 0.7 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat Ole-e-6 PF09253.5 ETO05223.1 - 0.2 11.3 0.2 0.2 11.3 0.1 1.7 2 0 0 2 2 2 0 Pollen allergen ole e 6 WD40 PF00400.27 ETO05225.1 - 2.4e-13 49.4 1.6 9.5e-12 44.3 0.2 2.4 2 1 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO05225.1 - 0.052 11.6 0.0 0.053 11.6 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Cas_Csm6 PF09659.5 ETO05226.1 - 0.015 13.9 0.4 0.015 13.9 0.2 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csm6) Ribosomal_L18e PF00828.14 ETO05226.1 - 0.1 13.0 0.0 0.16 12.3 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L18e/L15 Glycos_transf_2 PF00535.21 ETO05227.1 - 2.2e-13 50.2 0.1 1.3e-10 41.2 0.0 3.0 3 0 0 3 3 3 2 Glycosyl transferase family 2 DUF202 PF02656.10 ETO05227.1 - 2.5e-07 30.8 3.0 2.5e-07 30.8 2.1 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF202) SPX PF03105.14 ETO05227.1 - 3.8e-05 23.6 0.0 3.8e-05 23.6 0.0 2.8 3 1 0 3 3 3 1 SPX domain Glyco_tranf_2_3 PF13641.1 ETO05227.1 - 0.019 14.7 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase like family 2 DUF4391 PF14335.1 ETO05228.1 - 0.013 14.8 0.4 0.016 14.6 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) Ras PF00071.17 ETO05228.1 - 0.02 14.3 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Ras family TAFH PF07531.9 ETO05228.1 - 0.034 13.7 0.1 0.043 13.4 0.1 1.2 1 0 0 1 1 1 0 NHR1 homology to TAF COMP PF11598.3 ETO05230.1 - 0.028 14.4 0.1 0.077 13.0 0.1 1.7 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein FBPase PF00316.15 ETO05232.1 - 1.5e-118 395.3 0.0 1.8e-118 395.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 ETO05232.1 - 0.0053 16.0 0.0 0.038 13.2 0.0 2.3 3 0 0 3 3 3 1 Inositol monophosphatase family POR_N PF01855.14 ETO05233.1 - 0.055 12.9 1.5 0.15 11.5 1.1 1.8 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg EF_TS PF00889.14 ETO05234.1 - 0.81 8.9 10.2 4 6.6 3.1 2.3 2 0 0 2 2 2 0 Elongation factor TS WD40 PF00400.27 ETO05236.1 - 1.1e-72 237.5 10.9 3e-12 45.9 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO05236.1 - 3.4e-06 25.4 7.0 0.44 8.6 0.0 5.3 2 1 5 7 7 7 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO05236.1 - 1.9e-05 24.2 0.0 0.01 15.3 0.0 2.9 1 1 1 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 ETO05236.1 - 0.0002 20.2 12.7 0.17 10.6 0.1 5.0 2 2 3 5 5 5 3 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO05236.1 - 0.0019 16.5 3.1 0.36 9.0 0.0 3.4 3 1 1 4 4 4 3 Cytochrome D1 heme domain BBS2_Mid PF14783.1 ETO05236.1 - 0.003 17.2 3.5 1.6 8.5 0.1 5.0 2 2 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Mid2 PF04478.7 ETO05236.1 - 0.12 11.7 2.1 2.6 7.4 0.0 3.4 1 1 2 3 3 3 0 Mid2 like cell wall stress sensor DUF3732 PF12532.3 ETO05236.1 - 0.22 11.0 6.4 1.4 8.4 0.0 3.2 2 1 1 4 4 4 0 Protein of unknown function (DUF3732) Pkinase PF00069.20 ETO05237.1 - 1.1e-72 244.3 0.1 1.4e-72 243.9 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO05237.1 - 1.9e-39 135.3 0.1 1e-38 132.9 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO05237.1 - 0.00041 19.3 0.2 0.031 13.2 0.1 2.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETO05237.1 - 0.0012 18.0 0.4 0.0023 17.0 0.3 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO05237.1 - 0.015 15.0 0.3 0.051 13.3 0.1 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Peptidase_C97 PF05903.9 ETO05239.1 - 0.025 14.3 2.1 0.052 13.3 0.6 2.0 1 1 1 2 2 2 0 PPPDE putative peptidase domain Peroxin-13_N PF04088.8 ETO05239.1 - 0.65 9.9 4.1 2.4 8.0 0.0 2.4 3 0 0 3 3 3 0 Peroxin 13, N-terminal region DUF4337 PF14235.1 ETO05240.1 - 0.99 9.2 3.9 2 8.2 2.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF4407 PF14362.1 ETO05240.1 - 3 6.7 7.2 4.5 6.1 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UNC45-central PF11701.3 ETO05241.1 - 0.013 15.1 1.6 0.018 14.6 1.1 1.4 1 1 0 1 1 1 0 Myosin-binding striated muscle assembly central Ferric_reduct PF01794.14 ETO05243.1 - 1e-15 57.8 8.8 1.9e-15 57.0 6.1 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 ETO05243.1 - 2.7e-11 43.2 0.0 4.9e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.19 ETO05243.1 - 8.6e-06 25.8 0.0 1.8e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 ETO05244.1 - 4.3e-12 46.2 0.0 2e-11 44.0 0.0 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 ETO05244.1 - 0.024 15.2 0.1 0.14 12.7 0.0 2.1 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain VID27 PF08553.5 ETO05245.1 - 0.35 9.0 14.4 0.51 8.5 9.9 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein NST1 PF13945.1 ETO05245.1 - 1.4 8.9 20.6 3.4 7.6 14.3 1.6 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF1510 PF07423.6 ETO05245.1 - 9.2 5.5 18.1 0.3 10.4 8.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) U3_snoRNA_assoc PF08297.6 ETO05246.1 - 0.019 15.1 2.2 0.019 15.1 1.5 1.9 2 0 0 2 2 2 0 U3 snoRNA associated BEX PF04538.7 ETO05246.1 - 0.12 12.5 4.8 0.17 12.0 3.3 1.2 1 0 0 1 1 1 0 Brain expressed X-linked like family BRICHOS PF04089.9 ETO05246.1 - 1.9 8.3 4.6 10 6.0 3.2 2.0 1 1 0 1 1 1 0 BRICHOS domain DUF2217 PF10265.4 ETO05247.1 - 0.49 9.0 9.5 0.63 8.7 6.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) zf-TRAF PF02176.13 ETO05248.1 - 1.3e-05 25.4 3.9 1.3e-05 25.4 2.7 3.1 3 0 0 3 3 3 1 TRAF-type zinc finger Glyco_hydro_12 PF01670.11 ETO05248.1 - 0.018 14.8 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 12 DUF884 PF05959.6 ETO05248.1 - 0.083 12.1 0.5 0.19 11.0 0.3 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF884) zf-RING_2 PF13639.1 ETO05248.1 - 0.3 10.9 7.3 0.064 13.0 1.0 3.0 2 1 0 2 2 2 0 Ring finger domain TPR_12 PF13424.1 ETO05250.1 - 8.6e-47 156.9 18.9 1.8e-13 50.2 0.7 4.4 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETO05250.1 - 1.4e-25 88.6 12.9 7.6e-09 35.0 0.7 4.6 4 0 0 4 4 4 4 TPR repeat TPR_1 PF00515.23 ETO05250.1 - 1.7e-24 84.3 33.6 5.6e-07 28.8 1.8 7.2 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETO05250.1 - 3.3e-22 76.5 20.4 6.2e-05 22.6 1.3 6.7 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.1 ETO05250.1 - 1.8e-20 72.1 0.4 7e-06 25.7 0.1 6.8 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO05250.1 - 7.1e-19 66.1 31.2 0.0017 17.9 0.6 6.9 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.1 ETO05250.1 - 2.9e-17 60.9 6.4 0.00021 20.8 0.1 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETO05250.1 - 1.4e-09 37.3 2.1 0.65 10.3 0.1 7.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO05250.1 - 8.5e-07 29.0 6.1 3.9 8.1 0.2 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO05250.1 - 2.9e-05 24.5 0.0 0.041 14.5 0.0 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO05250.1 - 0.0011 19.1 15.4 0.045 13.8 3.7 3.8 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 C6_DPF PF10170.4 ETO05250.1 - 0.018 15.0 0.0 0.06 13.4 0.0 1.9 1 0 0 1 1 1 0 Cysteine-rich domain MIT PF04212.13 ETO05250.1 - 0.72 9.7 12.9 1.4 8.8 0.2 4.9 4 2 1 5 5 4 0 MIT (microtubule interacting and transport) domain Sel1 PF08238.7 ETO05250.1 - 1.7 9.3 10.9 11 6.8 0.5 4.3 4 0 0 4 4 4 0 Sel1 repeat Microcin PF03526.8 ETO05251.1 - 1.4 8.5 7.2 21 4.8 0.4 2.9 2 1 1 3 3 3 0 Colicin E1 (microcin) immunity protein WD40 PF00400.27 ETO05252.1 - 4.1e-69 226.1 16.8 3.4e-15 55.2 0.1 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO05252.1 - 1.1e-09 37.0 1.9 0.078 11.1 0.0 4.9 1 1 4 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO05252.1 - 2.3e-08 34.0 0.1 2e-05 24.4 0.0 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 ETO05252.1 - 3.8e-07 29.2 6.0 0.074 11.7 0.2 4.3 1 1 2 4 4 4 3 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO05252.1 - 1.8e-05 23.2 0.6 0.0058 14.9 0.0 3.1 1 1 2 3 3 3 3 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO05252.1 - 0.00033 20.2 0.2 0.022 14.2 0.2 2.9 1 1 0 1 1 1 1 PQQ-like domain DUF1258 PF06869.7 ETO05252.1 - 0.0034 16.5 0.9 1.2 8.2 0.0 3.3 2 2 2 4 4 4 1 Protein of unknown function (DUF1258) Nbas_N PF15492.1 ETO05252.1 - 0.0045 16.1 1.8 1.4 7.9 0.1 3.5 1 1 4 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Coatomer_WDAD PF04053.9 ETO05252.1 - 0.007 15.2 0.4 0.025 13.3 0.1 1.9 1 1 0 2 2 2 1 Coatomer WD associated region PLD_C PF12357.3 ETO05252.1 - 0.032 13.7 0.1 1.2e+02 2.3 0.0 5.1 6 1 1 7 7 7 0 Phospholipase D C terminal BBS2_Mid PF14783.1 ETO05252.1 - 0.06 13.1 2.1 3.4 7.4 0.1 3.8 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region DUF1797 PF08796.5 ETO05252.1 - 0.064 13.1 0.0 17 5.3 0.0 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF1797) Hira PF07569.6 ETO05252.1 - 0.093 11.9 0.6 23 4.1 0.0 3.9 2 2 5 7 7 7 0 TUP1-like enhancer of split PD40 PF07676.7 ETO05252.1 - 0.14 11.8 6.6 23 4.7 0.0 4.8 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 ETO05253.1 - 7.3e-47 155.6 6.5 4.1e-14 51.8 0.1 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO05253.1 - 0.0011 17.1 3.4 0.12 10.4 0.0 3.1 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO05253.1 - 0.0055 15.4 2.3 0.13 11.0 1.6 2.4 1 1 0 1 1 1 1 Nup133 N terminal like NYD-SP28_assoc PF14775.1 ETO05253.1 - 0.0071 16.0 1.6 17 5.1 0.0 3.9 4 0 0 4 4 4 1 Sperm tail C-terminal domain DUF727 PF05303.7 ETO05253.1 - 0.013 15.2 0.0 0.84 9.4 0.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF727) DUF1258 PF06869.7 ETO05253.1 - 0.028 13.4 0.1 1.3 8.0 0.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1258) TolB_N PF04052.8 ETO05253.1 - 0.071 13.1 0.0 4 7.5 0.0 2.5 2 0 0 2 2 2 0 TolB amino-terminal domain DUF3732 PF12532.3 ETO05253.1 - 0.12 11.8 0.1 10 5.5 0.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3732) adh_short PF00106.20 ETO05254.1 - 3.4e-11 43.3 0.0 1.1e-09 38.4 0.0 2.2 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETO05254.1 - 1.7e-09 37.7 0.0 0.00027 20.7 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETO05254.1 - 5.8e-05 22.8 0.0 0.0002 21.0 0.0 1.8 2 0 0 2 2 2 1 KR domain K1377 PF15352.1 ETO05254.1 - 0.0058 14.6 0.1 0.0095 13.9 0.1 1.2 1 0 0 1 1 1 1 Susceptibility to monomelic amyotrophy Ribosomal_S11 PF00411.14 ETO05254.1 - 0.075 13.2 0.2 0.29 11.3 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein S11 Metallophos_2 PF12850.2 ETO05256.1 - 5.1e-05 23.1 0.0 9.3e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 ETO05256.1 - 0.00024 20.5 0.0 0.00065 19.1 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Hat1_N PF10394.4 ETO05256.1 - 0.034 14.2 0.0 0.041 13.9 0.0 1.2 1 0 0 1 1 1 0 Histone acetyl transferase HAT1 N-terminus RE_HindVP PF09519.5 ETO05256.1 - 0.072 11.9 0.2 0.09 11.6 0.2 1.1 1 0 0 1 1 1 0 HindVP restriction endonuclease TPR_11 PF13414.1 ETO05257.1 - 2.7e-06 26.9 9.0 0.00059 19.4 0.9 2.6 1 1 1 2 2 2 2 TPR repeat TPR_17 PF13431.1 ETO05257.1 - 0.0008 19.4 1.3 0.15 12.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO05257.1 - 0.0011 19.2 1.2 0.013 15.7 1.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO05257.1 - 0.0013 19.3 0.8 0.0025 18.4 0.6 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO05257.1 - 0.004 17.6 1.0 0.04 14.5 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO05257.1 - 0.012 15.2 0.1 0.051 13.1 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETO05257.1 - 0.012 15.4 6.3 0.023 14.5 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TMEM156 PF15106.1 ETO05257.1 - 0.047 12.9 0.1 0.065 12.4 0.1 1.3 1 0 0 1 1 1 0 TMEM156 protein family TPR_7 PF13176.1 ETO05257.1 - 0.056 13.2 1.2 0.85 9.5 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 ETO05257.1 - 0.062 13.1 0.7 0.15 11.9 0.1 1.9 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_12 PF13424.1 ETO05257.1 - 0.13 12.2 1.9 0.4 10.6 1.1 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 ETO05257.1 - 0.85 9.7 4.5 0.59 10.3 0.7 2.3 2 1 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF748 PF05359.6 ETO05258.1 - 0.16 11.9 1.3 2.8 7.9 0.5 2.3 1 1 1 2 2 2 0 Domain of Unknown Function (DUF748) HTH_38 PF13936.1 ETO05259.1 - 0.16 11.5 2.8 0.31 10.6 0.6 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain Spt20 PF12090.3 ETO05259.1 - 0.59 9.4 14.7 1.4 8.2 4.8 2.6 2 0 0 2 2 2 0 Spt20 family Cation_efflux PF01545.16 ETO05260.1 - 0.012 14.6 6.2 0.012 14.6 4.3 2.1 1 1 1 2 2 2 0 Cation efflux family RDD PF06271.7 ETO05260.1 - 0.15 11.9 10.1 1.2 9.0 0.2 2.2 2 0 0 2 2 2 0 RDD family VKOR PF07884.9 ETO05260.1 - 0.28 11.0 10.7 0.035 13.9 3.9 1.9 1 1 1 2 2 2 0 Vitamin K epoxide reductase family RPA_interact_M PF14767.1 ETO05261.1 - 2.6 8.8 7.8 9.5 7.0 5.1 1.9 1 1 0 1 1 1 0 Replication protein A interacting middle RelA_SpoT PF04607.12 ETO05262.1 - 0.00052 19.9 2.3 0.0011 18.9 1.6 1.5 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins SRP54_N PF02881.14 ETO05263.1 - 0.11 12.5 2.3 2.1 8.5 0.0 3.4 3 0 0 3 3 3 0 SRP54-type protein, helical bundle domain Chitin_bind_4 PF00379.18 ETO05264.1 - 0.051 13.8 1.9 12 6.2 0.1 2.7 2 0 0 2 2 2 0 Insect cuticle protein Seryl_tRNA_N PF02403.17 ETO05265.1 - 0.014 15.3 3.7 0.038 14.0 2.5 1.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF2116 PF09889.4 ETO05265.1 - 0.026 14.3 1.5 0.084 12.6 1.0 1.9 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF3019 PF11456.3 ETO05265.1 - 6.2 7.2 9.9 0.78 10.0 1.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3019) FlaG PF03646.10 ETO05265.1 - 6.5 6.9 7.5 1.1 9.4 1.1 2.5 3 0 0 3 3 3 0 FlaG protein EF-hand_1 PF00036.27 ETO05266.1 - 2.3e-05 23.3 0.5 2.3e-05 23.3 0.3 2.4 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 ETO05266.1 - 0.00011 21.7 1.6 0.00024 20.6 0.6 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO05266.1 - 0.00091 18.9 0.6 0.00091 18.9 0.4 2.6 4 0 0 4 4 4 1 EF-hand domain EF-hand_5 PF13202.1 ETO05266.1 - 0.0039 16.4 0.3 0.0039 16.4 0.2 2.2 3 0 0 3 3 3 1 EF hand EF-hand_4 PF12763.2 ETO05266.1 - 0.005 16.5 0.4 0.0095 15.6 0.3 1.6 1 1 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 ETO05266.1 - 0.0066 16.5 0.1 0.0066 16.5 0.1 1.9 2 1 0 2 2 2 1 EF-hand domain pair Glyco_hydro_38C PF07748.8 ETO05267.1 - 5.9e-42 144.0 1.8 7.4e-34 117.3 0.1 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 ETO05267.1 - 1.9e-17 63.2 0.3 5.2e-17 61.8 0.2 1.8 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Glyco_hydro_38 PF01074.17 ETO05267.1 - 1e-11 44.6 0.3 2.7e-11 43.2 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Pkinase PF00069.20 ETO05268.1 - 4.7e-38 130.8 0.0 8.6e-38 129.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO05268.1 - 9.1e-18 64.2 0.0 4.6e-17 61.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO05268.1 - 3.6e-05 22.8 0.0 0.032 13.1 0.0 2.6 3 0 0 3 3 3 2 Kinase-like Pox_ser-thr_kin PF05445.6 ETO05268.1 - 0.024 13.4 0.1 0.047 12.4 0.1 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 ETO05268.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Macoilin PF09726.4 ETO05268.1 - 0.81 7.9 8.2 0.97 7.6 5.7 1.1 1 0 0 1 1 1 0 Transmembrane protein WD40 PF00400.27 ETO05269.1 - 6e-143 460.2 46.4 2.8e-12 46.0 0.2 16.6 16 0 0 16 16 16 15 WD domain, G-beta repeat NACHT PF05729.7 ETO05269.1 - 1e-09 38.2 0.0 2.3e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Pentapeptide PF00805.17 ETO05269.1 - 1e-05 24.6 1.2 2e-05 23.6 0.8 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) AAA_18 PF13238.1 ETO05269.1 - 6.2e-05 23.3 0.0 6.2e-05 23.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain Pentapeptide_4 PF13599.1 ETO05269.1 - 7.5e-05 22.4 0.7 0.00035 20.3 0.1 2.2 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) PQQ_2 PF13360.1 ETO05269.1 - 0.00013 21.4 1.3 0.0074 15.7 0.0 3.8 1 1 3 4 4 4 1 PQQ-like domain AAA_22 PF13401.1 ETO05269.1 - 0.00024 21.2 0.0 0.00095 19.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain Pentapeptide_3 PF13576.1 ETO05269.1 - 0.00086 19.1 0.4 0.0028 17.5 0.3 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA_17 PF13207.1 ETO05269.1 - 0.0017 19.1 0.1 0.048 14.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain PD40 PF07676.7 ETO05269.1 - 0.01 15.4 17.0 37 4.1 0.0 8.4 9 0 0 9 9 9 0 WD40-like Beta Propeller Repeat ABC_tran PF00005.22 ETO05269.1 - 0.094 13.0 2.4 0.67 10.2 0.0 3.1 3 0 0 3 3 2 0 ABC transporter WD40 PF00400.27 ETO05271.1 - 1.6e-81 265.5 20.1 4.9e-12 45.2 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO05271.1 - 1.1e-10 40.2 9.1 0.0051 15.0 0.5 5.2 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO05271.1 - 5.5e-07 28.6 12.9 0.75 8.4 0.0 6.1 1 1 3 4 4 4 4 Nup133 N terminal like PQQ_2 PF13360.1 ETO05271.1 - 7.3e-07 28.8 0.1 5.1e-06 26.1 0.0 2.3 1 1 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO05271.1 - 1.8e-05 23.2 0.2 0.0032 15.8 0.1 2.6 1 1 3 4 4 4 2 Cytochrome D1 heme domain Ricin_B_lectin PF00652.17 ETO05271.1 - 4.6e-05 23.4 0.9 1.8 8.6 0.0 3.1 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain Nbas_N PF15492.1 ETO05271.1 - 0.001 18.2 0.5 4.6 6.2 0.0 3.2 1 1 2 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Resistin PF06954.6 ETO05271.1 - 0.0012 19.0 0.1 7.5 6.9 0.0 3.5 2 1 1 3 3 3 1 Resistin PQQ_3 PF13570.1 ETO05271.1 - 0.0026 17.9 0.1 4.4 7.6 0.0 4.7 5 1 0 5 5 5 1 PQQ-like domain Me-amine-dh_H PF06433.6 ETO05271.1 - 0.011 14.3 0.1 0.034 12.7 0.0 1.8 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) DUF1797 PF08796.5 ETO05271.1 - 0.029 14.2 0.0 2.3 8.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1797) DPPIV_N PF00930.16 ETO05271.1 - 0.029 12.9 0.1 22 3.4 0.0 3.5 2 2 2 5 5 5 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region IKI3 PF04762.7 ETO05271.1 - 0.04 11.7 0.2 3.3 5.4 0.1 2.2 1 1 0 2 2 2 0 IKI3 family PD40 PF07676.7 ETO05271.1 - 0.049 13.3 9.0 12 5.7 0.0 5.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 ETO05272.1 - 5.8e-25 86.2 5.5 1.3e-11 43.9 0.0 4.6 4 1 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO05272.1 - 0.0002 19.6 0.4 0.046 11.8 0.1 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO05272.1 - 0.0015 18.2 1.7 0.53 10.0 0.1 3.3 1 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region DUF21 PF01595.15 ETO05274.1 - 2.5e-28 98.6 0.3 3.8e-28 98.0 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 ETO05274.1 - 1.3e-05 24.8 0.1 0.16 11.7 0.0 2.8 3 0 0 3 3 3 2 CBS domain DUF1469 PF07332.6 ETO05274.1 - 0.076 12.7 0.8 0.17 11.6 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) zf-TRAF PF02176.13 ETO05275.1 - 9.4e-07 29.1 3.3 9.4e-07 29.1 2.3 2.8 2 1 0 2 2 2 1 TRAF-type zinc finger zf-RING_2 PF13639.1 ETO05275.1 - 0.00046 19.9 4.9 0.031 14.0 0.5 2.8 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.1 ETO05275.1 - 0.00046 20.1 5.5 0.0068 16.4 0.6 3.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) TBPIP PF07106.8 ETO05275.1 - 0.0025 17.4 0.8 0.0044 16.5 0.6 1.4 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) zf-C3HC4_3 PF13920.1 ETO05275.1 - 0.17 11.6 9.4 3.3 7.4 2.3 3.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-H2C2_5 PF13909.1 ETO05275.1 - 0.69 10.2 0.1 0.69 10.2 0.1 3.2 2 2 1 3 3 3 0 C2H2-type zinc-finger domain RINGv PF12906.2 ETO05275.1 - 3.7 7.6 10.0 0.18 11.9 1.7 2.7 2 2 0 2 2 2 0 RING-variant domain DUF1644 PF07800.7 ETO05275.1 - 6.5 6.5 15.5 1e+02 2.6 10.8 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) WD40 PF00400.27 ETO05276.1 - 8.4e-23 79.3 17.9 1.1e-07 31.4 0.6 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO05276.1 - 0.027 14.1 0.2 7 6.2 0.0 2.7 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Tmemb_40 PF10160.4 ETO05276.1 - 0.028 13.6 0.3 0.043 13.0 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein Vfa1 PF08432.5 ETO05277.1 - 0.00042 20.3 7.8 0.00049 20.1 5.4 1.1 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Pro-NT_NN PF07421.6 ETO05279.1 - 0.14 11.5 0.6 0.15 11.5 0.4 1.1 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor Glyco_hydro_57 PF03065.10 ETO05280.1 - 0.0033 16.4 0.9 0.011 14.6 0.0 1.6 1 1 1 2 2 2 1 Glycosyl hydrolase family 57 DUF1410 PF07198.6 ETO05280.1 - 0.33 11.3 5.6 0.45 10.8 3.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1410) Senescence PF06911.7 ETO05281.1 - 5.1e-20 71.9 12.5 1e-19 70.9 8.7 1.5 1 0 0 1 1 1 1 Senescence-associated protein amfpi-1 PF12190.3 ETO05281.1 - 0.019 15.4 0.1 0.047 14.1 0.1 1.7 1 1 0 1 1 1 0 Fungal protease inhibitor HSP90 PF00183.13 ETO05282.1 - 1.9e-52 178.3 17.0 4e-32 111.3 5.7 2.1 1 1 1 2 2 2 2 Hsp90 protein AMMECR1 PF01871.12 ETO05282.1 - 0.025 13.7 0.1 0.047 12.8 0.1 1.5 1 0 0 1 1 1 0 AMMECR1 MCR_alpha_N PF02745.10 ETO05282.1 - 0.061 12.5 1.0 0.095 11.8 0.5 1.4 1 1 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, N-terminal domain Fanconi_A PF03511.9 ETO05284.1 - 0.021 14.5 0.1 0.043 13.5 0.1 1.5 1 0 0 1 1 1 0 Fanconi anaemia group A protein Bse634I PF07832.6 ETO05284.1 - 0.022 13.8 0.5 0.037 13.1 0.2 1.4 1 1 0 1 1 1 0 Cfr10I/Bse634I restriction endonuclease Sec5 PF15469.1 ETO05284.1 - 0.04 13.6 0.1 0.04 13.6 0.1 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec5 CAP_GLY PF01302.20 ETO05285.1 - 1.4e-05 24.6 0.3 2.6e-05 23.8 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain GP41 PF00517.12 ETO05285.1 - 3.7 7.0 6.4 15 5.0 1.6 2.2 2 0 0 2 2 2 0 Retroviral envelope protein B56 PF01603.15 ETO05286.1 - 1.1e-32 113.2 0.7 1.3e-32 112.9 0.5 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) WD40 PF00400.27 ETO05287.1 - 1e-82 269.2 13.3 5.7e-13 48.1 0.1 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO05287.1 - 4.5e-08 31.6 5.5 0.19 9.8 1.1 4.7 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO05287.1 - 3e-07 30.3 6.1 0.12 12.5 0.0 6.1 7 0 0 7 7 6 2 Kelch motif PD40 PF07676.7 ETO05287.1 - 1.4e-06 27.8 7.7 13 5.6 0.0 6.5 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO05287.1 - 2.2e-05 22.9 0.1 0.0018 16.6 0.0 2.5 1 1 2 3 3 3 1 Cytochrome D1 heme domain Kelch_2 PF07646.10 ETO05287.1 - 5e-05 22.8 2.2 0.091 12.5 0.1 4.8 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 ETO05287.1 - 0.00034 20.0 2.0 0.82 9.2 0.0 3.8 4 0 0 4 4 3 2 Kelch motif PQQ_2 PF13360.1 ETO05287.1 - 0.00047 19.6 0.1 0.001 18.5 0.1 1.7 1 1 0 1 1 1 1 PQQ-like domain Kelch_4 PF13418.1 ETO05287.1 - 0.0011 18.6 5.0 0.52 10.1 0.0 4.6 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO05287.1 - 0.0016 18.3 0.6 11 6.0 0.0 4.1 4 0 0 4 4 4 1 Kelch motif Proteasome_A_N PF10584.4 ETO05287.1 - 0.045 13.0 7.7 6.5 6.1 0.0 4.9 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Resistin PF06954.6 ETO05287.1 - 0.09 13.0 0.3 11 6.3 0.0 3.4 2 1 1 3 3 3 0 Resistin Gmad1 PF10647.4 ETO05287.1 - 0.25 10.7 0.0 1.2 8.4 0.0 2.0 1 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain zf-TRAF PF02176.13 ETO05289.1 - 0.00013 22.2 3.5 0.00013 22.2 2.4 2.7 2 0 0 2 2 2 1 TRAF-type zinc finger ABC_membrane PF00664.18 ETO05289.1 - 0.5 9.7 2.2 0.78 9.1 1.5 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region WD40 PF00400.27 ETO05290.1 - 2.2e-26 90.7 8.7 1.7e-10 40.3 0.1 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO05290.1 - 0.00034 18.8 0.8 0.4 8.7 0.0 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 DNA_primase_S PF01896.14 ETO05291.1 - 0.0038 17.0 0.2 0.0041 16.9 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit FHA PF00498.21 ETO05292.1 - 4.2e-07 29.9 0.4 8.5e-07 29.0 0.3 1.5 1 0 0 1 1 1 1 FHA domain MRI PF15325.1 ETO05292.1 - 0.0073 17.2 1.9 0.015 16.2 1.3 1.4 1 0 0 1 1 1 1 Modulator of retrovirus infection Ribosomal_L1 PF00687.16 ETO05293.1 - 0.1 11.9 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L1p/L10e family 2OG-FeII_Oxy_3 PF13640.1 ETO05294.1 - 0.00056 20.3 0.0 0.00082 19.8 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ndc80_HEC PF03801.8 ETO05297.1 - 1.5 8.2 7.4 5.3 6.4 1.0 2.8 1 1 3 4 4 3 0 HEC/Ndc80p family RabGAP-TBC PF00566.13 ETO05300.1 - 6.9e-11 42.0 2.5 1.1e-10 41.3 1.8 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Peptidase_M54 PF07998.6 ETO05301.1 - 0.00012 21.8 0.5 0.00025 20.8 0.4 1.5 1 0 0 1 1 1 1 Peptidase family M54 Peptidase_M10 PF00413.19 ETO05301.1 - 0.00035 20.3 0.1 0.00062 19.5 0.1 1.5 1 0 0 1 1 1 1 Matrixin Metallopep PF12044.3 ETO05301.1 - 0.00053 18.5 0.1 0.00053 18.5 0.1 1.9 2 0 0 2 2 2 1 Putative peptidase family DUF1025 PF06262.6 ETO05301.1 - 0.075 12.8 0.1 0.25 11.1 0.1 1.8 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase DUF3915 PF13054.1 ETO05301.1 - 0.076 12.9 5.9 0.21 11.5 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3915) Reprolysin_2 PF13574.1 ETO05301.1 - 0.077 13.0 2.7 0.1 12.6 0.1 2.3 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 ETO05301.1 - 0.095 13.2 3.7 0.14 12.7 0.2 2.6 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 ETO05301.1 - 0.12 12.2 2.9 0.1 12.5 0.5 2.1 2 0 0 2 2 2 0 Metallo-peptidase family M12 FAM176 PF14851.1 ETO05301.1 - 1.2 8.8 8.1 23 4.6 0.1 3.2 3 0 0 3 3 3 0 FAM176 family DUF912 PF06024.7 ETO05301.1 - 9.9 6.2 11.2 0.7 9.9 0.6 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) WD40 PF00400.27 ETO05302.1 - 2e-164 528.3 50.9 2.1e-12 46.3 0.7 16.1 16 0 0 16 16 16 16 WD domain, G-beta repeat Nup160 PF11715.3 ETO05302.1 - 1.3e-21 76.4 28.6 0.015 13.4 0.1 13.5 2 1 12 14 14 14 10 Nucleoporin Nup120/160 DUF1652 PF07865.6 ETO05302.1 - 1.3e-06 27.9 1.1 12 5.5 0.0 8.4 9 2 2 12 12 12 0 Protein of unknown function (DUF1652) PD40 PF07676.7 ETO05302.1 - 3.4e-06 26.5 21.2 0.87 9.3 0.1 9.4 10 0 0 10 10 10 1 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 ETO05302.1 - 5e-06 25.7 8.1 0.032 13.3 0.1 6.7 4 4 4 9 9 9 1 Protein of unknown function (DUF1258) F420_ligase PF01996.11 ETO05302.1 - 5.6e-06 25.5 0.0 2.5 7.0 0.0 4.6 5 0 0 5 5 5 2 F420-0:Gamma-glutamyl ligase Cytochrom_D1 PF02239.11 ETO05302.1 - 0.00036 18.9 8.9 0.73 8.0 0.0 5.6 4 1 0 6 6 6 2 Cytochrome D1 heme domain Resistin PF06954.6 ETO05302.1 - 0.013 15.7 0.3 27 5.1 0.0 5.1 5 1 1 6 6 6 0 Resistin DUF3732 PF12532.3 ETO05302.1 - 0.026 14.0 2.1 21 4.5 0.0 5.3 4 2 1 5 5 5 0 Protein of unknown function (DUF3732) Mid2 PF04478.7 ETO05302.1 - 0.075 12.4 12.6 8.2 5.8 0.0 6.8 5 3 3 8 8 8 0 Mid2 like cell wall stress sensor SusE PF14292.1 ETO05302.1 - 0.15 11.8 0.0 5.7 6.7 0.0 3.4 4 0 0 4 4 4 0 SusE outer membrane protein Peptidase_C69 PF03577.10 ETO05302.1 - 0.41 9.4 16.1 1.8 7.3 0.0 7.2 8 2 2 10 10 10 0 Peptidase family C69 POLO_box PF00659.13 ETO05302.1 - 0.49 10.4 9.3 26 4.8 0.0 6.5 8 0 0 8 8 8 0 POLO box duplicated region WD40 PF00400.27 ETO05303.1 - 8.1e-21 73.0 10.7 4.4e-10 39.0 0.3 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat N-glycanase_N PF09112.5 ETO05303.1 - 0.00016 21.0 0.7 0.00041 19.7 0.1 1.9 2 0 0 2 2 2 1 Peptide-N-glycosidase F, N terminal Nup160 PF11715.3 ETO05303.1 - 0.0034 15.6 4.1 0.0044 15.2 1.1 2.2 2 1 0 2 2 2 1 Nucleoporin Nup120/160 Apt1 PF10351.4 ETO05304.1 - 0.0076 15.1 0.3 0.0083 15.0 0.2 1.0 1 0 0 1 1 1 1 Golgi-body localisation protein domain TPR_12 PF13424.1 ETO05306.1 - 1.2e-101 332.8 10.2 1.3e-24 85.8 0.7 4.9 1 1 4 6 6 6 6 Tetratricopeptide repeat TPR_11 PF13414.1 ETO05306.1 - 1.4e-53 178.4 24.5 2.5e-16 59.0 0.4 4.2 2 1 3 5 5 5 5 TPR repeat TPR_10 PF13374.1 ETO05306.1 - 4.4e-48 159.8 0.0 7.4e-09 35.2 0.0 6.9 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETO05306.1 - 3.7e-45 149.7 30.3 3.6e-09 35.8 0.2 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.1 ETO05306.1 - 4.7e-39 129.0 4.7 3.8e-07 29.4 0.0 6.5 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_2 PF07719.12 ETO05306.1 - 4.7e-36 119.8 21.4 1.5e-06 27.6 0.4 6.9 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETO05306.1 - 5.1e-31 104.1 37.8 3.2e-08 32.7 0.8 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.1 ETO05306.1 - 2.4e-24 83.4 4.1 0.0046 17.0 0.0 6.9 6 1 0 6 6 6 5 Tetratricopeptide repeat TPR_6 PF13174.1 ETO05306.1 - 4.2e-14 51.9 1.3 0.03 14.7 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO05306.1 - 9.8e-14 51.2 27.5 5.6e-06 26.3 1.0 4.1 1 1 4 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 ETO05306.1 - 1.4e-13 50.1 0.0 0.14 12.8 0.0 6.0 6 1 1 7 7 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO05306.1 - 6.9e-13 48.8 0.0 0.00013 22.5 0.0 4.2 4 2 0 4 4 3 2 Tetratricopeptide repeat PPR PF01535.15 ETO05306.1 - 2.2e-11 42.8 15.0 0.039 13.9 0.1 6.9 7 0 0 7 7 7 3 PPR repeat TPR_19 PF14559.1 ETO05306.1 - 5.6e-11 42.6 0.1 0.039 14.2 0.0 4.4 2 1 1 4 4 4 3 Tetratricopeptide repeat MIT PF04212.13 ETO05306.1 - 1.6e-09 37.5 13.2 0.0095 15.7 0.4 5.5 6 0 0 6 6 5 3 MIT (microtubule interacting and transport) domain SNAP PF14938.1 ETO05306.1 - 1.7e-06 27.4 2.6 7.4e-05 22.0 0.1 3.0 1 1 3 4 4 4 3 Soluble NSF attachment protein, SNAP SHNi-TPR PF10516.4 ETO05306.1 - 4e-05 22.7 1.2 1 8.6 0.0 5.6 7 0 0 7 7 6 1 SHNi-TPR PPR_2 PF13041.1 ETO05306.1 - 0.00016 21.5 7.2 0.41 10.6 0.0 6.1 7 0 0 7 7 7 1 PPR repeat family Sel1 PF08238.7 ETO05306.1 - 0.0004 20.9 8.8 2.2 9.0 0.0 5.5 6 0 0 6 6 4 1 Sel1 repeat Pep3_Vps18 PF05131.9 ETO05306.1 - 0.00049 19.5 1.8 11 5.4 0.0 5.0 5 0 0 5 5 5 0 Pep3/Vps18/deep orange family KH_4 PF13083.1 ETO05306.1 - 0.00053 19.5 0.1 0.03 13.9 0.0 2.9 1 1 2 3 3 3 1 KH domain RPN7 PF10602.4 ETO05306.1 - 0.00062 19.1 8.6 0.46 9.8 0.1 4.0 1 1 2 3 3 3 2 26S proteasome subunit RPN7 TPR_3 PF07720.7 ETO05306.1 - 0.00064 19.4 16.6 1 9.2 0.3 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO05306.1 - 0.0018 18.1 12.0 1.7 8.5 0.2 5.1 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat DUF2225 PF09986.4 ETO05306.1 - 0.0019 17.7 7.4 0.33 10.3 0.2 3.9 1 1 2 4 4 4 2 Uncharacterized protein conserved in bacteria (DUF2225) PPR_1 PF12854.2 ETO05306.1 - 0.0028 17.1 2.7 3.4 7.2 0.1 5.0 6 0 0 6 6 5 1 PPR repeat DUF3568 PF12092.3 ETO05306.1 - 0.0096 15.6 0.0 19 4.9 0.0 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF3568) TPR_21 PF09976.4 ETO05306.1 - 0.01 15.7 1.2 0.11 12.4 0.0 3.1 3 2 0 3 3 3 0 Tetratricopeptide repeat DUF627 PF04781.7 ETO05306.1 - 0.046 13.3 8.8 1.1 8.8 0.6 4.9 2 1 3 5 5 5 0 Protein of unknown function (DUF627) SLT PF01464.15 ETO05306.1 - 0.073 12.5 2.7 20 4.6 0.0 3.5 2 1 2 4 4 4 0 Transglycosylase SLT domain Mob_Pre PF01076.14 ETO05306.1 - 0.077 12.6 2.1 6.4 6.3 0.0 2.9 2 1 1 3 3 3 0 Plasmid recombination enzyme FATC PF02260.15 ETO05306.1 - 0.16 11.4 0.1 32 4.0 0.0 3.1 3 0 0 3 3 3 0 FATC domain DUF2207 PF09972.4 ETO05307.1 - 0.00059 18.5 1.5 0.00078 18.1 1.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) TPR_7 PF13176.1 ETO05307.1 - 0.12 12.2 0.1 1.3 9.0 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat VIT1 PF01988.14 ETO05307.1 - 0.19 11.2 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 VIT family ETRAMP PF09716.5 ETO05307.1 - 0.21 11.5 6.4 0.6 10.1 0.4 2.6 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF4326 PF14216.1 ETO05307.1 - 0.59 10.7 4.5 0.29 11.7 0.5 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4326) DUF2361 PF10153.4 ETO05307.1 - 1.8 8.7 11.3 2.1 8.5 2.0 2.4 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2361) DUF4446 PF14584.1 ETO05307.1 - 6.4 6.5 6.4 2.4 7.9 1.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF4337 PF14235.1 ETO05307.1 - 7.4 6.3 6.6 0.67 9.7 1.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) WD40 PF00400.27 ETO05308.1 - 1.7e-35 119.5 12.0 1.3e-09 37.5 0.1 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO05308.1 - 0.00038 18.7 3.4 0.35 8.9 0.0 3.6 2 1 2 4 4 4 3 Nucleoporin Nup120/160 DUF2480 PF10652.4 ETO05308.1 - 0.027 14.0 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2480) Kelch_6 PF13964.1 ETO05308.1 - 0.6 10.3 6.1 22 5.4 0.0 4.5 4 1 1 5 5 5 0 Kelch motif SRP54 PF00448.17 ETO05310.1 - 0.017 14.5 0.3 0.033 13.6 0.2 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Folliculin PF11704.3 ETO05310.1 - 0.24 10.9 6.0 0.15 11.5 0.7 2.2 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport WD40 PF00400.27 ETO05311.1 - 6.3e-18 63.9 7.1 1.5e-13 50.0 0.2 3.1 3 1 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO05311.1 - 0.11 10.6 0.2 0.27 9.3 0.0 1.6 1 1 0 2 2 2 0 Nucleoporin Nup120/160 WD40 PF00400.27 ETO05312.1 - 2e-46 154.2 15.8 2.5e-12 46.1 0.1 6.4 6 1 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO05312.1 - 4.3e-09 35.0 0.5 0.026 12.6 0.0 3.8 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO05312.1 - 0.0013 17.5 5.6 0.29 9.8 1.6 3.5 1 1 2 3 3 3 2 Nup133 N terminal like DUF3601 PF12208.3 ETO05312.1 - 0.0018 18.1 0.1 0.089 12.7 0.0 3.1 2 1 0 3 3 3 1 Domain of unknown function (DUF3601) Med23 PF11573.3 ETO05313.1 - 0.012 13.0 2.0 0.015 12.7 1.4 1.0 1 0 0 1 1 1 0 Mediator complex subunit 23 Secretin_N_2 PF07655.8 ETO05313.1 - 2 8.8 12.3 3.2 8.2 8.5 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain DUF3300 PF11737.3 ETO05313.1 - 5.1 6.3 5.9 6.8 5.8 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3300) WD40 PF00400.27 ETO05314.1 - 1.1e-44 148.7 7.5 8e-09 35.0 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO05314.1 - 7.2e-06 24.4 4.7 0.37 8.8 0.7 4.3 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Peptidase_C69 PF03577.10 ETO05314.1 - 0.0016 17.3 0.0 0.13 11.1 0.0 2.2 2 0 0 2 2 2 2 Peptidase family C69 BBS2_Mid PF14783.1 ETO05314.1 - 0.0022 17.7 0.1 0.5 10.1 0.0 3.6 2 2 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region PD40 PF07676.7 ETO05314.1 - 0.047 13.3 0.7 14 5.4 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Mid2 PF04478.7 ETO05314.1 - 0.069 12.5 1.9 23 4.3 0.1 3.7 2 1 1 4 4 4 0 Mid2 like cell wall stress sensor NYD-SP28_assoc PF14775.1 ETO05314.1 - 0.075 12.7 0.3 4.9 6.9 0.0 3.6 4 0 0 4 4 4 0 Sperm tail C-terminal domain WD40 PF00400.27 ETO05315.1 - 7.2e-39 130.2 7.0 1.1e-10 40.9 0.1 5.0 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO05315.1 - 6.1e-07 27.9 5.5 0.072 11.2 0.4 3.6 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO05315.1 - 0.0023 16.7 3.9 0.075 11.7 0.3 2.7 1 1 2 3 3 3 2 Nup133 N terminal like DUF1797 PF08796.5 ETO05315.1 - 0.1 12.4 0.0 3.8 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1797) RasGEF PF00617.14 ETO05316.1 - 5e-28 98.1 4.3 8.1e-28 97.4 3.0 1.3 1 0 0 1 1 1 1 RasGEF domain PUB PF09409.5 ETO05317.1 - 4e-06 26.4 0.0 2.9e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 PUB domain Trypan_PARP PF05887.6 ETO05317.1 - 0.02 14.7 5.7 0.039 13.7 3.9 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF2457 PF10446.4 ETO05317.1 - 0.088 11.5 16.4 0.18 10.4 11.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF605 PF04652.11 ETO05317.1 - 0.11 11.8 28.4 0.15 11.3 19.7 1.3 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 ETO05317.1 - 0.33 9.1 27.8 0.38 8.9 19.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neurochondrin PF05536.6 ETO05318.1 - 0.00014 20.2 2.4 0.043 12.1 0.0 2.9 1 1 2 3 3 3 3 Neurochondrin Ric8 PF10165.4 ETO05318.1 - 0.094 11.5 0.0 1.1 7.9 0.0 2.0 1 1 0 1 1 1 0 Guanine nucleotide exchange factor synembryn Atx10homo_assoc PF09759.4 ETO05319.1 - 9.7e-07 28.4 3.2 2e-05 24.2 0.5 2.4 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Neurochondrin PF05536.6 ETO05319.1 - 1.4e-05 23.6 1.4 0.0093 14.3 0.2 2.3 1 1 1 2 2 2 2 Neurochondrin Arm PF00514.18 ETO05319.1 - 0.0031 17.2 7.4 0.37 10.6 0.0 5.0 4 1 0 5 5 5 1 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.9 ETO05319.1 - 0.0044 16.1 0.1 0.012 14.7 0.1 1.7 1 1 0 1 1 1 1 V-ATPase subunit H Ric8 PF10165.4 ETO05319.1 - 0.0073 15.1 0.1 0.15 10.8 0.1 2.5 1 1 0 1 1 1 1 Guanine nucleotide exchange factor synembryn KAP PF05804.7 ETO05319.1 - 0.015 13.2 2.5 0.33 8.8 0.1 2.1 1 1 1 2 2 2 0 Kinesin-associated protein (KAP) Arm_2 PF04826.8 ETO05319.1 - 0.027 13.5 2.4 0.29 10.1 0.0 2.1 1 1 1 2 2 2 0 Armadillo-like Proteasom_PSMB PF10508.4 ETO05319.1 - 0.048 11.9 0.3 0.18 9.9 0.0 2.0 1 1 1 2 2 2 0 Proteasome non-ATPase 26S subunit HEAT_2 PF13646.1 ETO05319.1 - 0.048 13.9 0.0 0.75 10.1 0.0 2.7 2 1 0 2 2 2 0 HEAT repeats MoeZ_MoeB PF05237.8 ETO05319.1 - 0.1 12.2 0.0 0.4 10.2 0.0 2.0 2 0 0 2 2 2 0 MoeZ/MoeB domain Arm PF00514.18 ETO05320.1 - 0.00024 20.8 6.3 66 3.5 0.1 7.8 7 2 2 9 9 9 0 Armadillo/beta-catenin-like repeat DUF3135 PF11333.3 ETO05320.1 - 0.0018 18.3 0.2 1.7 8.8 0.0 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3135) TetR_C_5 PF08360.6 ETO05320.1 - 0.002 18.0 0.2 0.029 14.3 0.0 2.4 2 0 0 2 2 2 1 QacR-like protein, C-terminal region HHH_5 PF14520.1 ETO05320.1 - 0.0026 17.8 0.8 1.6 8.9 0.0 3.8 3 0 0 3 3 3 1 Helix-hairpin-helix domain RTTN_N PF14726.1 ETO05320.1 - 0.0043 17.6 1.3 1.1 9.8 0.0 4.2 3 1 1 4 4 4 1 Rotatin, an armadillo repeat protein, centriole functioning Exo70 PF03081.10 ETO05320.1 - 0.027 13.2 0.1 0.59 8.8 0.1 2.1 2 0 0 2 2 2 0 Exo70 exocyst complex subunit Rrf2 PF02082.15 ETO05320.1 - 0.046 13.8 0.0 1.4 9.0 0.0 2.9 2 0 0 2 2 2 0 Transcriptional regulator PEP-utilisers_N PF05524.8 ETO05320.1 - 0.051 13.3 0.6 0.25 11.1 0.2 2.3 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Cdd1 PF11731.3 ETO05320.1 - 0.12 12.3 0.1 4.4 7.3 0.0 3.3 3 1 0 3 3 3 0 Pathogenicity locus CSTF2_hinge PF14327.1 ETO05320.1 - 0.2 11.7 3.1 19 5.4 0.1 3.9 3 1 0 3 3 3 0 Hinge domain of cleavage stimulation factor subunit 2 DUF3361 PF11841.3 ETO05321.1 - 0.00027 20.7 0.0 0.00061 19.5 0.0 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF3361) Lambda_Kil PF06301.6 ETO05321.1 - 0.019 14.3 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage lambda Kil protein Hormone_recep PF00104.25 ETO05321.1 - 0.081 12.0 0.0 0.2 10.7 0.0 1.6 1 1 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor VID27 PF08553.5 ETO05323.1 - 0.0033 15.7 6.6 0.0045 15.3 4.6 1.2 1 0 0 1 1 1 1 VID27 cytoplasmic protein DUF1510 PF07423.6 ETO05323.1 - 0.012 14.9 15.7 0.019 14.3 10.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) HSP90 PF00183.13 ETO05323.1 - 0.096 11.0 13.4 0.13 10.6 9.3 1.1 1 0 0 1 1 1 0 Hsp90 protein Caldesmon PF02029.10 ETO05323.1 - 0.14 10.5 14.6 0.18 10.2 10.1 1.1 1 0 0 1 1 1 0 Caldesmon Zip PF02535.17 ETO05323.1 - 0.14 11.1 1.1 0.2 10.6 0.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.7 ETO05323.1 - 0.33 8.8 20.9 0.43 8.4 14.5 1.2 1 0 0 1 1 1 0 Nop14-like family DUF740 PF05340.7 ETO05323.1 - 0.87 7.8 10.9 1.1 7.5 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Vfa1 PF08432.5 ETO05323.1 - 0.89 9.5 13.8 1.5 8.8 9.6 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Daxx PF03344.10 ETO05323.1 - 1.1 7.6 19.4 1.3 7.4 13.5 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 ETO05323.1 - 4.6 5.1 18.0 6.9 4.5 12.5 1.2 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.11 ETO05323.1 - 8.5 5.2 12.1 20 4.0 8.4 1.6 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Kelch_6 PF13964.1 ETO05324.1 - 0.00054 20.0 0.6 0.012 15.7 0.0 3.3 4 1 1 5 5 5 1 Kelch motif Kelch_4 PF13418.1 ETO05324.1 - 0.0021 17.7 1.9 0.053 13.2 0.0 3.5 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO05324.1 - 0.0032 17.1 0.4 0.015 15.0 0.2 2.2 1 0 0 1 1 1 1 Kelch motif Kelch_1 PF01344.20 ETO05324.1 - 0.011 15.2 0.6 0.054 13.0 0.1 2.4 3 0 0 3 3 3 0 Kelch motif DUF987 PF06174.6 ETO05324.1 - 0.027 13.9 0.0 0.066 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF987) Kelch_5 PF13854.1 ETO05324.1 - 0.1 12.6 0.3 3.7 7.6 0.1 3.0 3 0 0 3 3 3 0 Kelch motif NACHT PF05729.7 ETO05325.1 - 3.5e-13 49.5 0.0 7.1e-13 48.5 0.0 1.5 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETO05325.1 - 2.5e-05 24.3 0.1 0.00037 20.5 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 ETO05325.1 - 0.0019 17.0 0.6 0.003 16.4 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain DUF2075 PF09848.4 ETO05325.1 - 0.011 14.7 0.0 0.15 11.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 ETO05325.1 - 0.023 14.8 0.1 0.064 13.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 ETO05325.1 - 0.078 12.7 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain Torsin PF06309.6 ETO05325.1 - 0.092 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_18 PF13238.1 ETO05325.1 - 0.11 12.8 0.1 0.28 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain HEAT_2 PF13646.1 ETO05326.1 - 1.9e-10 40.8 0.0 2.7e-06 27.5 0.0 4.9 1 1 4 6 6 6 2 HEAT repeats Ank_2 PF12796.2 ETO05326.1 - 1.1e-09 38.4 0.0 6.6e-09 35.9 0.0 2.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) HEAT PF02985.17 ETO05326.1 - 1.4e-09 37.1 0.0 0.46 10.7 0.0 8.6 8 0 0 8 8 8 1 HEAT repeat Ank_3 PF13606.1 ETO05326.1 - 1.2e-08 34.4 0.1 7.9e-05 22.5 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 ETO05326.1 - 4.9e-08 33.2 0.2 2.3e-07 31.1 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO05326.1 - 1.3e-07 31.6 0.1 2.3e-06 27.6 0.0 2.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) HEAT_EZ PF13513.1 ETO05326.1 - 1e-05 25.8 0.0 0.17 12.3 0.0 5.5 4 1 1 5 5 5 2 HEAT-like repeat Ank PF00023.25 ETO05326.1 - 9.9e-05 21.9 0.1 0.0095 15.7 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat HEAT_PBS PF03130.11 ETO05326.1 - 0.094 13.2 0.0 5.1 7.8 0.0 3.3 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat Ldh_1_N PF00056.18 ETO05328.1 - 0.00043 20.1 0.0 0.00081 19.2 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Coat_X PF07552.6 ETO05328.1 - 0.08 12.7 2.2 0.21 11.3 1.5 1.7 1 0 0 1 1 1 0 Spore Coat Protein X and V domain IncA PF04156.9 ETO05330.1 - 9 5.8 11.5 18 4.8 7.9 1.6 1 1 0 1 1 1 0 IncA protein eIF3_N PF09440.5 ETO05332.1 - 0.027 14.6 5.0 0.34 11.0 3.4 2.4 1 1 0 1 1 1 0 eIF3 subunit 6 N terminal domain NLBH PF05211.7 ETO05332.1 - 1.6 7.8 9.8 2.8 7.1 3.4 2.2 1 1 1 2 2 2 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) BRCA-2_OB3 PF09104.5 ETO05333.1 - 0.029 14.1 1.0 0.034 13.9 0.7 1.1 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 Ofd1_CTDD PF10637.4 ETO05333.1 - 0.073 12.1 1.1 0.078 12.1 0.8 1.1 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term MRP-S23 PF10484.4 ETO05333.1 - 0.13 12.1 0.1 0.23 11.3 0.0 1.4 1 1 0 1 1 1 0 Mitochondrial ribosomal protein S23 AAA_14 PF13173.1 ETO05333.1 - 0.16 11.8 1.7 0.18 11.7 1.2 1.1 1 0 0 1 1 1 0 AAA domain DUSP PF06337.7 ETO05334.1 - 4.9 7.6 8.5 0.24 11.8 0.6 2.2 1 1 1 2 2 2 0 DUSP domain DUF106 PF01956.11 ETO05335.1 - 0.016 14.7 0.0 0.051 13.1 0.0 1.9 1 1 0 1 1 1 0 Integral membrane protein DUF106 IncA PF04156.9 ETO05335.1 - 0.071 12.6 9.6 0.092 12.3 6.6 1.3 1 0 0 1 1 1 0 IncA protein RCR PF12273.3 ETO05335.1 - 0.24 11.9 0.1 0.24 11.9 0.1 2.2 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Protocadherin PF08374.6 ETO05335.1 - 0.49 9.9 11.1 0.12 11.9 1.4 2.2 2 0 0 2 2 2 0 Protocadherin DUF1754 PF08555.5 ETO05335.1 - 0.5 10.9 19.0 0.077 13.5 3.8 2.6 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) FYDLN_acid PF09538.5 ETO05335.1 - 3 8.4 18.7 6.8 7.3 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Bud13 PF09736.4 ETO05336.1 - 6.6 6.9 11.6 8.4 6.6 8.1 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex TPR_12 PF13424.1 ETO05338.1 - 1.8e-17 63.0 1.1 1.1e-13 50.9 0.1 2.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO05338.1 - 2e-12 45.9 0.7 0.00064 19.3 0.0 4.0 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO05338.1 - 4.3e-12 45.0 7.2 1e-05 24.9 0.4 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO05338.1 - 8.8e-12 44.5 0.0 0.00056 19.7 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO05338.1 - 2.8e-11 42.4 6.6 7.2e-06 25.5 0.3 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO05338.1 - 3.4e-09 36.2 10.9 1.1e-06 28.2 3.2 3.5 1 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.1 ETO05338.1 - 0.00016 21.1 12.5 0.012 15.3 0.7 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO05338.1 - 0.00016 20.8 1.9 0.8 9.0 0.0 3.9 4 1 0 4 4 4 2 SHNi-TPR Apc3 PF12895.2 ETO05338.1 - 0.00037 20.5 4.0 0.0035 17.4 2.8 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 ETO05338.1 - 0.0077 16.8 0.0 0.85 10.3 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 ETO05338.1 - 0.033 14.0 8.9 0.43 10.4 0.5 4.1 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.1 ETO05338.1 - 0.033 14.8 0.0 0.27 11.9 0.0 2.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETO05338.1 - 0.083 13.2 0.0 0.24 11.7 0.0 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO05338.1 - 0.12 12.2 2.4 1.9 8.4 0.1 3.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DUF4413 PF14372.1 ETO05338.1 - 0.2 11.6 1.8 0.97 9.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4413) TPR_17 PF13431.1 ETO05338.1 - 2 8.8 10.5 0.47 10.7 2.1 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat SecA_DEAD PF07517.9 ETO05340.1 - 5.3e-12 45.5 0.4 1.4e-09 37.6 0.0 2.5 2 0 0 2 2 2 2 SecA DEAD-like domain HSCB_C PF07743.8 ETO05340.1 - 0.047 14.1 2.4 11 6.4 0.0 3.2 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain AAA PF00004.24 ETO05340.1 - 0.071 13.3 0.2 0.48 10.6 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cys_rich_VLP PF14194.1 ETO05340.1 - 0.078 12.7 0.4 0.24 11.1 0.1 1.9 2 0 0 2 2 2 0 Cysteine-rich VLP HSP90 PF00183.13 ETO05341.1 - 4.5e-06 25.3 1.9 4.6e-05 22.0 0.0 2.3 1 1 2 3 3 3 2 Hsp90 protein DUF3974 PF13120.1 ETO05341.1 - 0.022 14.6 0.4 0.022 14.6 0.3 2.2 1 1 1 3 3 3 0 Domain of unknown function (DUF3974) HSP90 PF00183.13 ETO05342.1 - 2.3e-41 141.8 4.9 5.1e-21 74.6 0.3 2.0 1 1 1 2 2 2 2 Hsp90 protein INCENP_ARK-bind PF03941.10 ETO05343.1 - 0.059 13.2 0.6 0.18 11.6 0.4 1.8 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region DUF4266 PF14086.1 ETO05343.1 - 8.6 6.9 8.8 1.4 9.4 1.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4266) Exo_endo_phos PF03372.18 ETO05344.1 - 0.00012 22.0 0.0 0.00018 21.4 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SPRY PF00622.23 ETO05345.1 - 6.3e-29 100.5 0.3 1.4e-28 99.4 0.2 1.7 1 0 0 1 1 1 1 SPRY domain zf-RanBP PF00641.13 ETO05345.1 - 3.3e-06 26.1 10.9 0.0025 16.8 1.2 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.10 ETO05345.1 - 0.0005 19.5 1.1 0.032 13.8 0.1 2.6 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger DZR PF12773.2 ETO05345.1 - 0.11 12.3 8.6 0.41 10.5 6.0 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 ETO05345.1 - 1.4 8.2 8.7 0.076 12.2 0.6 2.3 2 0 0 2 2 2 0 zinc-ribbon domain HECT PF00632.20 ETO05346.1 - 1.1e-70 238.2 1.4 3.5e-70 236.6 0.1 2.5 2 1 1 3 3 3 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.13 ETO05346.1 - 4.6e-05 22.4 1.3 0.00015 20.8 0.9 1.9 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.10 ETO05346.1 - 0.025 14.1 0.1 0.091 12.3 0.0 1.9 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger MT0933_antitox PF14013.1 ETO05348.1 - 0.035 14.1 2.0 0.06 13.4 1.4 1.4 1 0 0 1 1 1 0 MT0933-like antitoxin protein Sin_N PF04801.8 ETO05348.1 - 0.11 11.2 4.6 0.2 10.4 1.9 1.9 2 0 0 2 2 2 0 Sin-like protein conserved region U1snRNP70_N PF12220.3 ETO05348.1 - 0.39 11.0 9.7 0.79 10.0 6.5 1.7 1 1 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF788 PF05620.6 ETO05348.1 - 0.7 9.7 5.5 0.56 10.0 2.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF788) VWA_2 PF13519.1 ETO05350.1 - 1.2e-05 25.5 0.0 0.00013 22.1 0.0 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain DUF496 PF04363.7 ETO05350.1 - 0.043 13.6 7.5 0.025 14.4 3.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF496) Laminin_I PF06008.9 ETO05351.1 - 7.4e-06 25.4 6.8 1.5e-05 24.4 4.7 1.5 1 0 0 1 1 1 1 Laminin Domain I PhoU_div PF01865.11 ETO05351.1 - 0.006 15.7 5.2 0.017 14.2 2.1 2.1 2 0 0 2 2 2 1 Protein of unknown function DUF47 HemX PF04375.9 ETO05351.1 - 0.013 14.0 6.8 0.019 13.5 4.7 1.2 1 0 0 1 1 1 0 HemX CENP-F_leu_zip PF10473.4 ETO05351.1 - 0.037 13.8 4.6 0.09 12.6 3.2 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 OMS28_porin PF03532.8 ETO05351.1 - 0.043 12.8 3.0 0.093 11.7 2.0 1.5 1 1 0 1 1 1 0 OMS28 porin RmuC PF02646.11 ETO05351.1 - 0.14 10.9 8.1 0.025 13.4 1.6 2.2 2 1 1 3 3 3 0 RmuC family HlyD PF00529.15 ETO05351.1 - 0.17 11.1 10.1 0.24 10.6 7.0 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Laminin_II PF06009.7 ETO05351.1 - 0.22 11.2 9.0 0.98 9.1 3.8 2.7 2 1 1 3 3 3 0 Laminin Domain II DUF4164 PF13747.1 ETO05351.1 - 0.25 11.5 4.5 0.2 11.8 0.6 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) Tropomyosin_1 PF12718.2 ETO05351.1 - 0.26 11.1 9.3 0.028 14.2 2.5 2.0 2 1 0 2 2 2 0 Tropomyosin like DUF948 PF06103.6 ETO05351.1 - 0.62 9.9 8.8 3.6 7.5 3.3 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4527 PF15030.1 ETO05351.1 - 1 8.6 4.2 2.1 7.5 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) ERM PF00769.14 ETO05351.1 - 3.6 7.0 14.2 0.97 8.9 7.4 1.9 2 1 0 2 2 2 0 Ezrin/radixin/moesin family DUF1492 PF07374.6 ETO05351.1 - 4.6 7.4 8.3 1.2 9.2 1.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1492) DUF1664 PF07889.7 ETO05351.1 - 5.6 6.7 11.4 3.7 7.3 4.6 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) WD40 PF00400.27 ETO05352.1 - 8.6e-09 34.9 0.1 0.0024 17.6 0.0 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat WD40 PF00400.27 ETO05353.1 - 2.1e-81 265.1 17.1 5.4e-13 48.2 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO05353.1 - 3e-08 32.2 9.4 0.049 11.7 0.5 5.1 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO05353.1 - 1.7e-07 30.3 8.5 0.076 11.7 0.0 5.4 1 1 3 5 5 5 4 Nup133 N terminal like PQQ_2 PF13360.1 ETO05353.1 - 5.4e-07 29.3 0.4 0.0006 19.3 0.1 3.0 1 1 1 2 2 2 2 PQQ-like domain Cytochrom_D1 PF02239.11 ETO05353.1 - 1e-06 27.3 1.7 0.011 14.0 0.1 3.4 1 1 1 3 3 3 2 Cytochrome D1 heme domain PD40 PF07676.7 ETO05353.1 - 0.023 14.3 3.1 83 3.0 0.0 5.1 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 ETO05353.1 - 0.048 12.7 1.8 3.2 6.7 0.0 3.8 1 1 4 5 5 5 0 Neuroblastoma-amplified sequence, N terminal Ricin_B_lectin PF00652.17 ETO05353.1 - 0.27 11.2 4.5 1.7 8.7 1.7 2.9 2 1 1 3 3 3 0 Ricin-type beta-trefoil lectin domain WD40 PF00400.27 ETO05354.1 - 5.1e-21 73.7 8.6 4.1e-11 42.3 1.5 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO05354.1 - 5.6e-05 21.4 1.2 0.00051 18.3 0.2 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 WD40 PF00400.27 ETO05355.1 - 7.8e-161 516.9 41.4 3.3e-11 42.6 0.1 16.2 16 0 0 16 16 16 16 WD domain, G-beta repeat eIF2A PF08662.6 ETO05355.1 - 1.6e-10 41.0 5.9 0.0085 15.8 0.1 5.8 3 2 2 6 6 6 3 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 ETO05355.1 - 2.4e-07 30.1 10.7 3.4 6.7 0.0 7.9 4 4 5 9 9 9 3 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 ETO05355.1 - 3.5e-06 25.5 13.4 0.16 10.2 0.1 5.6 3 3 3 6 6 6 3 Cytochrome D1 heme domain Pentapeptide PF00805.17 ETO05355.1 - 7.5e-06 25.0 0.2 1.6e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Mid2 PF04478.7 ETO05355.1 - 0.00036 19.9 15.1 2.3 7.6 0.0 7.8 8 2 1 10 10 10 2 Mid2 like cell wall stress sensor Pentapeptide_4 PF13599.1 ETO05355.1 - 0.00038 20.2 0.4 0.0017 18.1 0.0 2.2 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) PD40 PF07676.7 ETO05355.1 - 0.012 15.2 15.5 27 4.5 0.0 9.4 11 0 0 11 11 11 0 WD40-like Beta Propeller Repeat Pentapeptide_3 PF13576.1 ETO05355.1 - 0.02 14.7 0.0 0.067 13.0 0.0 1.9 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) Peptidase_C69 PF03577.10 ETO05355.1 - 0.11 11.4 4.8 1.2 7.9 0.0 4.8 6 1 0 6 6 6 0 Peptidase family C69 His_Phos_2 PF00328.17 ETO05357.1 - 0.00013 21.4 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) WD40 PF00400.27 ETO05359.1 - 3.7e-76 248.5 22.3 7.8e-13 47.7 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Resistin PF06954.6 ETO05359.1 - 1.9e-05 24.8 0.2 7.1 6.9 0.0 5.0 1 1 5 6 6 6 1 Resistin Nbas_N PF15492.1 ETO05359.1 - 2.2e-05 23.6 1.8 3.8 6.5 0.0 4.4 1 1 4 5 5 5 2 Neuroblastoma-amplified sequence, N terminal DUF1258 PF06869.7 ETO05359.1 - 0.0001 21.4 0.4 6.7 5.7 0.0 4.3 1 1 3 5 5 5 2 Protein of unknown function (DUF1258) PQQ_2 PF13360.1 ETO05359.1 - 0.00011 21.7 0.1 0.00021 20.8 0.0 1.5 1 0 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO05359.1 - 0.00015 20.2 0.3 0.34 9.1 0.0 3.1 3 0 0 3 3 3 2 Cytochrome D1 heme domain PD40 PF07676.7 ETO05359.1 - 0.00073 19.1 13.1 1.3 8.7 0.1 6.4 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat Str_synth PF03088.11 ETO05359.1 - 0.0008 19.4 0.2 0.18 11.8 0.0 4.2 3 1 3 6 6 6 1 Strictosidine synthase AcetylCoA_hyd_C PF13336.1 ETO05359.1 - 0.0019 17.8 0.1 9.3 5.8 0.0 3.5 2 1 2 4 4 4 1 Acetyl-CoA hydrolase/transferase C-terminal domain Coatomer_WDAD PF04053.9 ETO05359.1 - 0.0028 16.5 0.2 0.47 9.1 0.0 2.8 1 1 1 3 3 3 1 Coatomer WD associated region DPPIV_N PF00930.16 ETO05359.1 - 0.033 12.7 0.1 6.7 5.1 0.0 3.2 2 1 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nucleoporin_N PF08801.6 ETO05359.1 - 0.041 12.6 6.3 3.8 6.1 4.4 3.7 1 1 0 1 1 1 0 Nup133 N terminal like DUF1797 PF08796.5 ETO05359.1 - 0.051 13.4 0.0 3.9 7.4 0.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1797) PLD_C PF12357.3 ETO05359.1 - 0.089 12.3 0.6 48 3.5 0.0 4.2 4 1 0 5 5 5 0 Phospholipase D C terminal Proteasome_A_N PF10584.4 ETO05359.1 - 3.6 7.0 0.0 3.6 7.0 0.0 5.2 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature Pro_isomerase PF00160.16 ETO05360.1 - 6.7e-44 149.8 0.3 8.1e-44 149.5 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF2011 PF09428.5 ETO05361.1 - 0.00039 20.3 0.2 0.0008 19.3 0.1 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) tRNA_anti-codon PF01336.20 ETO05362.1 - 2.2e-08 33.8 0.2 4.7e-08 32.7 0.2 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RPA_C PF08784.6 ETO05362.1 - 4.6e-05 23.7 0.5 0.00017 21.9 0.3 2.0 1 1 0 1 1 1 1 Replication protein A C terminal tRNA_anti_2 PF13742.1 ETO05362.1 - 0.0029 17.4 0.0 0.0056 16.5 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain WD40 PF00400.27 ETO05363.1 - 9.5e-43 142.6 25.6 2.7e-12 46.0 1.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO05363.1 - 0.00059 18.0 6.2 0.86 7.6 0.1 4.0 2 1 2 4 4 4 4 Nucleoporin Nup120/160 REJ PF02010.10 ETO05364.1 - 0.00012 20.6 4.9 0.00083 17.7 0.6 2.4 1 1 1 2 2 2 2 REJ domain DUF2499 PF10693.4 ETO05364.1 - 0.034 14.1 0.8 0.19 11.7 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2499) mRNA_cap_enzyme PF01331.14 ETO05365.1 - 1.7e-06 27.8 1.1 2.1e-06 27.5 0.7 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain Tcf25 PF04910.9 ETO05367.1 - 0.021 13.7 0.2 0.022 13.6 0.1 1.1 1 0 0 1 1 1 0 Transcriptional repressor TCF25 NYN_YacP PF05991.6 ETO05367.1 - 0.032 13.9 0.3 0.038 13.7 0.2 1.1 1 0 0 1 1 1 0 YacP-like NYN domain Atrophin-1 PF03154.10 ETO05368.1 - 1.3 7.0 7.8 2.8 5.9 5.4 1.5 1 0 0 1 1 1 0 Atrophin-1 family Tubulin PF00091.20 ETO05371.1 - 1.7e-33 116.2 0.3 3e-23 82.7 0.2 2.2 1 1 1 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO05371.1 - 0.02 14.9 0.1 0.035 14.1 0.1 1.3 1 0 0 1 1 1 0 Tubulin C-terminal domain CcmD PF04995.9 ETO05374.1 - 1.9 8.2 4.6 1.5 8.5 0.4 2.9 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) TPR_12 PF13424.1 ETO05375.1 - 4.1e-55 183.6 2.1 3.8e-21 74.8 0.1 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO05375.1 - 5.7e-42 141.2 21.1 4e-13 48.8 1.3 4.2 1 1 4 5 5 5 5 TPR repeat TPR_1 PF00515.23 ETO05375.1 - 3e-35 118.3 24.4 1.3e-07 30.9 0.1 5.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.1 ETO05375.1 - 3.5e-33 110.7 0.5 8.6e-06 25.1 0.0 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 ETO05375.1 - 1e-29 100.0 21.1 7e-08 31.7 0.1 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETO05375.1 - 7.7e-29 98.7 0.0 8e-06 25.6 0.0 5.3 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETO05375.1 - 9.7e-29 96.9 10.2 4.1e-05 23.1 0.0 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 ETO05375.1 - 1.4e-08 34.2 8.1 0.55 10.5 0.0 7.8 6 1 1 7 7 7 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO05375.1 - 7.8e-07 28.2 0.2 0.96 8.7 0.0 5.3 5 1 0 5 5 5 2 SHNi-TPR TPR_14 PF13428.1 ETO05375.1 - 8.8e-07 29.0 0.0 12 6.8 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO05375.1 - 1.4e-06 28.3 0.5 2.1 9.0 0.0 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat MIT PF04212.13 ETO05375.1 - 2.1e-06 27.5 9.7 0.32 10.8 0.0 5.3 4 1 1 5 5 5 2 MIT (microtubule interacting and transport) domain DUF2225 PF09986.4 ETO05375.1 - 3.6e-06 26.6 7.3 0.0087 15.5 0.3 3.9 1 1 3 4 4 4 3 Uncharacterized protein conserved in bacteria (DUF2225) TPR_16 PF13432.1 ETO05375.1 - 6.9e-06 26.5 0.0 0.84 10.3 0.0 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO05375.1 - 3.1e-05 24.0 11.4 0.0082 16.2 1.0 3.8 1 1 4 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 ETO05375.1 - 0.00015 21.4 11.4 0.0039 16.9 0.2 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat PPR PF01535.15 ETO05375.1 - 0.0012 18.6 7.5 0.78 9.8 0.0 5.2 5 0 0 5 5 5 1 PPR repeat Sel1 PF08238.7 ETO05375.1 - 0.0014 19.1 4.3 4.3 8.1 0.0 4.9 5 0 0 5 5 5 1 Sel1 repeat Sec66 PF09802.4 ETO05375.1 - 0.065 12.6 1.0 0.15 11.4 0.7 1.6 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 NSF PF02071.15 ETO05375.1 - 0.17 12.5 11.0 1.1e+02 4.1 0.0 5.8 5 0 0 5 5 5 0 Aromatic-di-Alanine (AdAR) repeat WD40 PF00400.27 ETO05376.1 - 1.3e-56 186.5 5.5 2e-12 46.4 0.1 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO05376.1 - 1e-08 33.8 1.6 0.005 15.0 0.0 3.8 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO05376.1 - 0.00096 17.5 0.4 0.0036 15.6 0.0 2.1 2 1 1 3 3 3 1 Cytochrome D1 heme domain PLD_C PF12357.3 ETO05376.1 - 0.0052 16.2 0.3 1.1 8.8 0.0 3.5 2 1 2 4 4 4 1 Phospholipase D C terminal IKI3 PF04762.7 ETO05376.1 - 0.0079 14.0 0.4 0.33 8.7 0.1 2.0 1 1 1 2 2 2 2 IKI3 family DUF3627 PF12299.3 ETO05376.1 - 0.016 15.2 0.0 0.32 11.0 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3627) B3_4 PF03483.12 ETO05376.1 - 0.053 12.9 0.0 0.19 11.1 0.0 2.0 1 1 1 2 2 2 0 B3/4 domain NHL PF01436.16 ETO05376.1 - 0.11 12.4 0.1 1 9.4 0.0 2.3 2 0 0 2 2 2 0 NHL repeat IL33 PF15095.1 ETO05378.1 - 0.0011 18.4 0.3 0.0019 17.6 0.2 1.4 1 0 0 1 1 1 1 Interleukin 33 zf-TRAF PF02176.13 ETO05379.1 - 0.00018 21.7 1.6 0.00018 21.7 1.1 2.7 2 0 0 2 2 2 1 TRAF-type zinc finger AAA_13 PF13166.1 ETO05379.1 - 0.0072 14.8 35.1 0.012 14.1 24.4 1.2 1 0 0 1 1 1 1 AAA domain DUF3584 PF12128.3 ETO05379.1 - 1.4 6.1 32.7 4.1 4.6 22.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 ETO05379.1 - 2.2 7.3 5.9 1.2 8.2 1.8 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF641 PF04859.7 ETO05379.1 - 9.8 5.9 30.4 0.12 12.0 4.0 4.0 1 1 3 4 4 4 0 Plant protein of unknown function (DUF641) WD40 PF00400.27 ETO05380.1 - 9e-31 104.6 4.2 3e-09 36.4 0.2 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO05380.1 - 5.6e-05 21.6 0.2 0.0021 16.3 0.1 2.0 1 1 0 1 1 1 1 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 ETO05380.1 - 0.0018 17.1 1.8 0.0022 16.8 1.2 1.1 1 0 0 1 1 1 1 Coatomer WD associated region Hira PF07569.6 ETO05380.1 - 0.0095 15.1 1.4 0.67 9.1 0.1 3.0 1 1 2 3 3 3 1 TUP1-like enhancer of split DUF3877 PF12993.2 ETO05380.1 - 0.041 13.4 1.4 0.13 11.8 0.1 2.1 1 1 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) Peptidase_S49_N PF08496.5 ETO05381.1 - 0.078 12.7 2.0 0.12 12.1 1.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal MCM PF00493.18 ETO05382.1 - 0.00068 18.5 0.7 0.0013 17.5 0.1 1.7 1 1 1 2 2 2 1 MCM2/3/5 family AAA PF00004.24 ETO05382.1 - 0.012 15.7 0.1 0.53 10.4 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETO05382.1 - 0.013 15.6 0.1 0.044 13.9 0.0 1.8 1 1 1 2 2 2 0 AAA domain Tmpp129 PF10272.4 ETO05382.1 - 0.022 13.5 0.6 0.025 13.3 0.4 1.1 1 0 0 1 1 1 0 Putative transmembrane protein precursor ABC_tran PF00005.22 ETO05382.1 - 0.042 14.1 0.1 0.069 13.4 0.0 1.4 1 1 0 1 1 1 0 ABC transporter ResIII PF04851.10 ETO05382.1 - 0.069 12.9 0.7 0.15 11.8 0.3 1.8 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit WW PF00397.21 ETO05384.1 - 5.7e-08 32.4 9.4 2.3e-05 24.1 2.6 2.5 2 0 0 2 2 2 2 WW domain DUF2147 PF09917.4 ETO05384.1 - 0.52 10.5 4.4 0.44 10.8 2.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2147) Macoilin PF09726.4 ETO05384.1 - 4.3 5.5 23.1 5.3 5.1 16.0 1.0 1 0 0 1 1 1 0 Transmembrane protein Atracotoxin PF05353.6 ETO05385.1 - 0.07 12.9 0.5 0.16 11.7 0.4 1.6 1 0 0 1 1 1 0 Delta Atracotoxin WD40 PF00400.27 ETO05386.1 - 4.3e-58 191.2 28.5 1.1e-10 41.0 0.0 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO05386.1 - 2.3e-07 29.3 6.4 0.18 9.9 0.0 5.6 1 1 3 5 5 5 3 Nucleoporin Nup120/160 DUF851 PF05867.6 ETO05386.1 - 0.012 14.9 0.0 2.6 7.2 0.0 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF851) TPR_1 PF00515.23 ETO05386.1 - 0.098 12.2 0.1 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETO05386.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO05386.1 - 0.12 12.2 0.1 0.29 11.0 0.1 1.6 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Fib_alpha PF08702.5 ETO05387.1 - 1.8 8.6 7.4 0.72 9.9 3.4 1.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1777 PF08648.7 ETO05387.1 - 4.9 6.8 16.2 40 3.8 10.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1777) FtsK_SpoIIIE_N PF12538.3 ETO05388.1 - 0.015 15.4 0.1 0.024 14.7 0.1 1.3 1 0 0 1 1 1 0 DNA transporter PUB PF09409.5 ETO05390.1 - 0.00085 19.0 0.3 0.0034 17.1 0.2 1.9 1 1 0 1 1 1 1 PUB domain PCI PF01399.22 ETO05390.1 - 0.075 13.3 0.8 0.31 11.3 0.1 2.0 1 1 1 2 2 2 0 PCI domain Tubulin PF00091.20 ETO05392.1 - 3.9e-22 79.1 0.4 4.4e-22 78.9 0.3 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Gly_acyl_tr_C PF08444.5 ETO05393.1 - 0.12 12.4 3.2 0.14 12.1 0.8 2.1 1 1 2 3 3 3 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Exo_endo_phos_2 PF14529.1 ETO05394.1 - 2.6e-16 59.3 0.0 5.2e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 ETO05394.1 - 0.0016 18.4 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DDHD PF02862.12 ETO05394.1 - 0.92 9.2 5.2 16 5.2 1.2 2.3 2 0 0 2 2 2 0 DDHD domain HlyD PF00529.15 ETO05395.1 - 0.0002 20.7 9.7 0.00023 20.5 6.7 1.1 1 0 0 1 1 1 1 HlyD family secretion protein RmuC PF02646.11 ETO05395.1 - 0.011 14.5 3.9 0.011 14.5 2.7 2.5 2 1 1 3 3 3 0 RmuC family PY_rept_46 PF09689.5 ETO05395.1 - 0.24 11.7 2.3 0.27 11.5 0.1 2.1 2 0 0 2 2 2 0 Plasmodium yoelii repeat (PY_rept_46) Tht1 PF04163.7 ETO05395.1 - 0.38 9.1 7.8 0.48 8.7 5.4 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein DUF4449 PF14613.1 ETO05395.1 - 1.2 9.0 10.6 0.2 11.5 4.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) Laminin_II PF06009.7 ETO05395.1 - 1.3 8.7 10.6 6 6.6 6.6 2.3 1 1 1 2 2 2 0 Laminin Domain II DUF1664 PF07889.7 ETO05395.1 - 1.9 8.2 11.2 1.5 8.6 5.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF2229 PF09989.4 ETO05395.1 - 4.2 6.7 6.5 6.8 6.0 4.3 1.5 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Y_phosphatase3 PF13350.1 ETO05395.1 - 6.6 6.9 8.9 6.7 6.9 3.4 2.0 1 1 1 2 2 2 0 Tyrosine phosphatase family DUF948 PF06103.6 ETO05395.1 - 6.7 6.6 13.1 15 5.5 3.6 3.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4446 PF14584.1 ETO05395.1 - 8.2 6.2 14.4 6.8 6.5 1.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) AAA_23 PF13476.1 ETO05395.1 - 9.6 6.4 13.5 13 6.0 9.3 1.3 1 0 0 1 1 1 0 AAA domain Peptidase_C3 PF00548.15 ETO05397.1 - 0.099 12.4 0.4 0.19 11.5 0.3 1.4 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) TLP-20 PF06088.6 ETO05397.1 - 0.29 10.7 7.7 0.62 9.7 5.4 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) SNF2_N PF00176.18 ETO05399.1 - 1.1e-45 155.6 0.0 1.4e-45 155.3 0.0 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 ETO05400.1 - 5.1e-09 35.8 17.5 5.1e-09 35.8 12.1 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 ETO05400.1 - 4.8e-08 32.5 19.3 4.8e-08 32.5 13.4 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO05400.1 - 9.3e-08 31.6 14.7 9.3e-08 31.6 10.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO05400.1 - 1.2e-06 28.3 20.4 1.2e-06 28.3 14.2 2.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO05400.1 - 0.0002 21.0 17.5 0.0002 21.0 12.2 2.9 1 1 1 2 2 2 1 zinc-RING finger domain U-box PF04564.10 ETO05400.1 - 0.00078 19.3 0.1 0.0029 17.5 0.0 2.0 2 0 0 2 2 2 1 U-box domain zf-C3HC4_4 PF15227.1 ETO05400.1 - 0.00086 19.1 18.8 0.00086 19.1 13.0 2.1 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING SNF2_N PF00176.18 ETO05400.1 - 0.002 17.0 0.9 0.0028 16.5 0.1 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-rbx1 PF12678.2 ETO05400.1 - 0.003 17.6 14.7 0.016 15.3 10.2 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger Helicase_C PF00271.26 ETO05400.1 - 0.014 15.2 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain zf-Apc11 PF12861.2 ETO05400.1 - 0.031 14.1 9.4 0.12 12.2 6.5 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 ETO05400.1 - 0.06 13.0 14.3 0.21 11.3 9.9 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-C2H2_2 PF12756.2 ETO05400.1 - 1.5 8.9 12.5 0.63 10.1 6.2 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-RING_6 PF14835.1 ETO05400.1 - 3.1 7.6 13.1 0.11 12.2 4.7 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Rad50_zn_hook PF04423.9 ETO05400.1 - 3.1 7.3 14.1 0.2 11.1 3.7 2.7 3 0 0 3 3 3 0 Rad50 zinc hook motif WD40 PF00400.27 ETO05401.1 - 4.2e-12 45.4 0.1 1.8e-05 24.4 0.0 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat WD40 PF00400.27 ETO05402.1 - 1e-12 47.4 0.2 7.2e-08 32.0 0.1 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat HSP70 PF00012.15 ETO05403.1 - 1.7e-06 26.2 0.0 5.2e-05 21.3 0.0 2.1 2 0 0 2 2 2 2 Hsp70 protein Hydantoinase_A PF01968.13 ETO05403.1 - 0.04 13.0 0.0 0.099 11.7 0.0 1.6 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase TelA PF05816.6 ETO05403.1 - 0.24 10.0 0.5 0.39 9.3 0.3 1.3 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) UQ_con PF00179.21 ETO05404.1 - 0.021 14.2 0.5 0.032 13.6 0.3 1.3 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme BcrAD_BadFG PF01869.15 ETO05405.1 - 0.083 12.1 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Takusan PF04822.8 ETO05407.1 - 0.0056 16.4 9.1 0.0064 16.2 5.8 1.5 1 1 0 1 1 1 1 Takusan Zeta_toxin PF06414.7 ETO05407.1 - 0.12 11.4 1.0 0.14 11.2 0.7 1.1 1 0 0 1 1 1 0 Zeta toxin DivIC PF04977.10 ETO05407.1 - 0.68 9.4 6.9 1.3 8.5 4.4 1.8 1 1 0 1 1 1 0 Septum formation initiator V_ATPase_I PF01496.14 ETO05407.1 - 0.98 7.1 9.5 0.81 7.4 6.0 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family TSC22 PF01166.13 ETO05407.1 - 2.1 8.4 7.3 6 6.9 2.6 2.5 1 1 1 2 2 2 0 TSC-22/dip/bun family ORF6C PF10552.4 ETO05407.1 - 2.1 8.0 10.1 2.7 7.7 1.5 2.3 1 1 1 2 2 2 0 ORF6C domain bZIP_1 PF00170.16 ETO05407.1 - 3.3 7.7 16.0 0.59 10.1 8.3 1.9 2 1 0 2 2 2 0 bZIP transcription factor Sec20 PF03908.8 ETO05408.1 - 0.0068 16.0 0.5 0.021 14.5 0.3 1.9 1 1 0 1 1 1 1 Sec20 RAB3GAP2_C PF14656.1 ETO05408.1 - 0.014 13.6 0.0 0.019 13.1 0.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus bZIP_1 PF00170.16 ETO05409.1 - 0.0044 16.9 4.9 0.0044 16.9 3.4 7.6 2 1 4 7 7 7 2 bZIP transcription factor DUF2051 PF09738.4 ETO05409.1 - 0.0075 15.5 24.2 0.0075 15.5 16.8 3.7 2 1 0 3 3 3 1 Double stranded RNA binding protein (DUF2051) GAS PF13851.1 ETO05409.1 - 0.0099 15.0 69.9 0.086 12.0 19.5 4.1 2 1 2 4 4 4 3 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 ETO05409.1 - 1.8 7.6 19.9 5.4 6.0 1.9 2.8 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DASH_Dam1 PF08653.5 ETO05409.1 - 7.5 6.4 13.8 6.4 6.6 0.7 4.2 4 0 0 4 4 4 0 DASH complex subunit Dam1 DUF3450 PF11932.3 ETO05409.1 - 8.6 5.5 51.1 0.49 9.6 10.0 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) WD40 PF00400.27 ETO05410.1 - 2.3e-20 71.6 2.9 7.9e-10 38.2 0.1 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO05410.1 - 0.0048 15.6 0.5 0.013 14.2 0.4 1.7 1 1 0 1 1 1 1 Nup133 N terminal like Borrelia_P83 PF05262.6 ETO05410.1 - 0.044 12.0 0.0 0.056 11.7 0.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Nup160 PF11715.3 ETO05410.1 - 0.065 11.3 0.1 0.53 8.3 0.0 1.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Cdc6_C PF09079.6 ETO05411.1 - 0.0018 17.9 0.0 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 CDC6, C terminal Penicillinase_R PF03965.11 ETO05411.1 - 0.025 14.6 1.2 0.051 13.6 0.0 2.0 2 0 0 2 2 2 0 Penicillinase repressor HTH_27 PF13463.1 ETO05411.1 - 0.093 13.0 0.0 0.41 11.0 0.0 2.0 2 0 0 2 2 2 0 Winged helix DNA-binding domain MarR PF01047.17 ETO05411.1 - 0.12 12.1 0.1 0.3 10.7 0.0 1.7 1 0 0 1 1 1 0 MarR family NRDE PF05742.7 ETO05412.1 - 0.0079 15.5 0.1 0.013 14.8 0.1 1.3 1 0 0 1 1 1 1 NRDE protein Apolipoprotein PF01442.13 ETO05417.1 - 0.024 14.1 5.9 0.031 13.7 4.1 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain PCNP PF15473.1 ETO05417.1 - 0.084 13.1 0.7 0.11 12.8 0.5 1.3 1 0 0 1 1 1 0 PEST, proteolytic signal-containing nuclear protein family Baculo_PEP_C PF04513.7 ETO05417.1 - 0.12 12.1 8.4 0.22 11.3 5.6 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PBP1_TM PF14812.1 ETO05417.1 - 0.47 10.7 5.0 0.11 12.8 0.9 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ENTH PF01417.15 ETO05417.1 - 0.69 9.7 8.2 4.1 7.2 3.9 2.8 1 1 1 2 2 2 0 ENTH domain Slu7 PF11708.3 ETO05417.1 - 0.78 9.4 11.7 0.93 9.1 2.6 2.1 1 1 1 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor Tweety PF04906.8 ETO05417.1 - 1.1 7.5 4.3 1.5 7.1 3.0 1.1 1 0 0 1 1 1 0 Tweety DUF1640 PF07798.6 ETO05417.1 - 7.6 6.5 17.0 2.1 8.3 1.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) 14-3-3 PF00244.15 ETO05419.1 - 9.6e-17 60.8 27.7 1.8e-13 50.1 0.9 3.9 3 1 1 4 4 4 3 14-3-3 protein Man-6-P_recep PF02157.10 ETO05420.1 - 0.024 13.6 0.0 0.027 13.4 0.0 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate receptor zf-C3HC4_2 PF13923.1 ETO05420.1 - 0.25 11.4 4.6 0.46 10.5 1.4 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.15 ETO05420.1 - 7.6 6.1 9.1 0.18 11.3 0.8 2.4 3 1 0 3 3 3 0 MIZ/SP-RING zinc finger Hydrolase_3 PF08282.7 ETO05421.1 - 0.00027 20.5 0.2 0.00042 19.9 0.2 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETO05421.1 - 0.11 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 ETO05421.1 - 0.62 9.5 15.3 0.012 15.0 3.8 2.4 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus Inositol_P PF00459.20 ETO05422.1 - 1.7e-39 135.7 0.1 2.2e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family zf-C3HC4_2 PF13923.1 ETO05423.1 - 0.016 15.2 3.3 0.064 13.2 0.9 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.15 ETO05423.1 - 0.91 9.0 6.3 0.11 12.0 1.1 1.9 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger zf-C3HC4 PF00097.20 ETO05423.1 - 1 9.0 5.3 10 5.8 0.9 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.20 ETO05424.1 - 6.5e-37 127.0 0.0 9e-37 126.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO05424.1 - 3.3e-18 65.7 0.0 4.8e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO05424.1 - 0.025 13.5 0.0 0.038 12.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 ETO05424.1 - 0.065 12.2 0.4 0.2 10.6 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SAC3_GANP PF03399.11 ETO05425.1 - 1.3e-05 24.8 10.9 2.7e-05 23.8 7.5 1.6 1 1 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Herpes_capsid PF06112.6 ETO05427.1 - 0.061 13.3 16.2 0.085 12.8 11.2 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF3731 PF12531.3 ETO05427.1 - 0.16 11.4 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 DNA-K related protein Arm PF00514.18 ETO05428.1 - 4.2e-08 32.7 0.2 0.0035 17.1 0.0 2.4 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 ETO05428.1 - 0.032 14.4 0.0 0.069 13.4 0.0 1.5 1 0 0 1 1 1 0 HEAT repeats Acetyltransf_1 PF00583.19 ETO05429.1 - 5e-05 23.2 0.1 0.45 10.5 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETO05429.1 - 0.00013 22.0 4.8 0.013 15.6 0.1 3.1 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Apis_Csd PF11671.3 ETO05429.1 - 0.018 14.8 5.8 0.064 13.0 4.0 1.9 1 0 0 1 1 1 0 Complementary sex determiner protein DUF1974 PF09317.6 ETO05429.1 - 0.25 10.6 3.5 0.072 12.4 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1974) DUF3439 PF11921.3 ETO05429.1 - 7.1 6.4 13.9 23 4.7 9.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Methyltransf_12 PF08242.7 ETO05430.1 - 0.057 13.9 2.4 0.1 13.0 1.6 1.4 1 0 0 1 1 1 0 Methyltransferase domain Menin PF05053.8 ETO05430.1 - 0.51 8.4 4.8 0.64 8.1 3.3 1.1 1 0 0 1 1 1 0 Menin Secretin_N_2 PF07655.8 ETO05430.1 - 0.91 9.9 14.3 1.6 9.1 9.9 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain Apc15p PF05841.6 ETO05430.1 - 1.9 9.2 9.8 3.1 8.5 6.8 1.2 1 0 0 1 1 1 0 Apc15p protein DUF912 PF06024.7 ETO05430.1 - 7.6 6.6 9.2 15 5.6 6.4 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Nitroreductase PF00881.19 ETO05432.1 - 0.04 13.7 0.0 0.095 12.5 0.0 1.6 2 0 0 2 2 2 0 Nitroreductase family Pkinase PF00069.20 ETO05436.1 - 3.5e-51 173.8 0.1 8.9e-51 172.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO05436.1 - 2.3e-18 66.2 0.1 4.7e-18 65.1 0.1 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 ETO05436.1 - 0.0026 17.1 0.1 2.1 7.6 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.15 ETO05436.1 - 0.0089 15.6 0.1 0.015 14.9 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 ETO05436.1 - 0.01 14.6 0.8 0.024 13.4 0.1 1.7 1 1 1 2 2 2 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 ETO05436.1 - 0.021 13.8 0.0 0.031 13.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF2744 PF10910.3 ETO05436.1 - 0.11 12.3 0.0 0.44 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2744) APH PF01636.18 ETO05436.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Annexin PF00191.15 ETO05437.1 - 3.6e-28 97.2 1.6 3.9e-11 42.7 0.0 4.3 4 0 0 4 4 4 4 Annexin DUF2528 PF10800.3 ETO05437.1 - 0.012 15.9 0.1 6.4 7.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2528) HupH_C PF04809.8 ETO05439.1 - 0.022 14.4 0.2 0.1 12.3 0.0 2.1 2 1 0 2 2 2 0 HupH hydrogenase expression protein, C-terminal conserved region VCX_VCY PF15231.1 ETO05441.1 - 0.052 13.9 0.1 0.08 13.3 0.0 1.3 1 0 0 1 1 1 0 Variable charge X/Y family DUF1900 PF08954.6 ETO05441.1 - 1.1 8.7 5.6 0.27 10.7 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1900) Erythro-docking PF09277.6 ETO05442.1 - 3.1 7.5 6.4 2.5 7.8 0.7 2.3 1 1 1 2 2 2 0 Erythronolide synthase, docking VirE2 PF07229.7 ETO05447.1 - 0.0054 15.1 6.7 0.0061 15.0 4.7 1.0 1 0 0 1 1 1 1 VirE2 DUF2320 PF10082.4 ETO05447.1 - 1.1 7.9 9.5 1.3 7.6 6.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2320) Casc1 PF12366.3 ETO05448.1 - 0.37 10.2 6.8 0.44 10.0 4.7 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 PEX11 PF05648.9 ETO05448.1 - 0.5 9.5 2.7 0.72 9.0 1.8 1.2 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) DUF1754 PF08555.5 ETO05448.1 - 1.2 9.7 18.5 0.28 11.7 10.7 1.6 1 1 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) RNA_pol_3_Rpc31 PF11705.3 ETO05448.1 - 2.7 7.8 14.0 4.4 7.1 9.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF3464 PF11947.3 ETO05448.1 - 4 6.8 7.2 6.9 6.1 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) FAM60A PF15396.1 ETO05448.1 - 7.6 6.2 9.5 8.2 6.1 6.6 1.2 1 0 0 1 1 1 0 Protein Family FAM60A ATG_C PF09333.6 ETO05449.1 - 1.6e-07 31.3 0.1 1.3e-06 28.4 0.0 2.3 2 0 0 2 2 2 1 ATG C terminal domain DUF3752 PF12572.3 ETO05450.1 - 0.00013 22.1 4.0 0.00028 21.0 2.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) DUF1162 PF06650.7 ETO05450.1 - 0.00062 19.0 2.2 0.0022 17.2 1.5 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1162) Cnd1_N PF12922.2 ETO05450.1 - 0.21 11.2 3.3 0.16 11.6 1.0 1.7 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term Serglycin PF04360.7 ETO05450.1 - 0.22 11.2 6.3 0.25 11.0 3.0 2.1 2 0 0 2 2 2 0 Serglycin SR-25 PF10500.4 ETO05450.1 - 6.2 6.2 13.7 2.8 7.3 4.1 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Pollen_allerg_1 PF01357.16 ETO05451.1 - 6.1e-06 25.9 3.6 7.1e-05 22.5 0.1 2.4 1 1 1 2 2 2 2 Pollen allergen FtsL PF04999.8 ETO05452.1 - 0.094 12.4 0.1 0.29 10.8 0.0 1.7 1 1 1 2 2 2 0 Cell division protein FtsL DUF1201 PF06716.6 ETO05452.1 - 0.47 10.2 6.1 0.64 9.8 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1201) Methyltransf_21 PF05050.7 ETO05453.1 - 3e-05 24.0 0.2 0.00095 19.1 0.1 2.7 3 0 0 3 3 3 1 Methyltransferase FkbM domain Nefa_Nip30_N PF10187.4 ETO05453.1 - 0.12 12.5 3.7 0.27 11.4 2.6 1.6 1 0 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF2633 PF11119.3 ETO05454.1 - 0.014 15.0 0.4 0.07 12.8 0.3 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) GPS PF01825.16 ETO05454.1 - 0.055 13.5 5.0 0.15 12.1 3.4 1.7 1 0 0 1 1 1 0 Latrophilin/CL-1-like GPS domain REJ PF02010.10 ETO05455.1 - 6.6e-06 24.6 1.2 0.0026 16.1 0.0 2.1 2 0 0 2 2 2 2 REJ domain FCH PF00611.18 ETO05456.1 - 3.6e-07 30.2 0.1 5.6e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Arch_ATPase PF01637.13 ETO05456.1 - 0.0026 17.4 0.4 0.0046 16.6 0.1 1.6 1 1 0 2 2 2 1 Archaeal ATPase PepX_N PF09168.5 ETO05456.1 - 0.039 14.1 0.2 0.55 10.4 0.0 2.1 1 1 1 2 2 2 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal Sec8_exocyst PF04048.9 ETO05456.1 - 0.077 12.6 0.5 4.4 6.9 0.0 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain ArsR PF09824.4 ETO05456.1 - 0.089 12.1 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 ArsR transcriptional regulator DUF1359 PF07097.6 ETO05456.1 - 0.29 11.1 1.9 1.1 9.3 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1359) PBP1_TM PF14812.1 ETO05458.1 - 0.31 11.3 7.5 0.64 10.3 1.0 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Kelch_1 PF01344.20 ETO05458.1 - 3.8 7.1 7.8 1.6 8.3 0.1 4.0 5 0 0 5 5 5 0 Kelch motif Apis_Csd PF11671.3 ETO05458.1 - 4.5 7.0 13.7 1 9.1 4.6 2.4 2 0 0 2 2 2 0 Complementary sex determiner protein WD40 PF00400.27 ETO05459.1 - 6.2e-24 82.9 4.8 2.1e-09 36.9 0.2 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat WD40 PF00400.27 ETO05460.1 - 7.7e-25 85.8 6.6 1.1e-08 34.5 0.3 4.2 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO05460.1 - 1.6e-06 26.6 0.5 0.1 10.6 0.0 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 UpxZ PF06603.6 ETO05460.1 - 0.088 12.8 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 UpxZ family of transcription anti-terminator antagonists Kelch_6 PF13964.1 ETO05460.1 - 0.23 11.6 2.9 2.2 8.5 0.2 3.0 3 0 0 3 3 3 0 Kelch motif HECT PF00632.20 ETO05461.1 - 1.5e-54 185.3 0.1 1.7e-54 185.1 0.1 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) FBP PF07299.6 ETO05461.1 - 0.055 12.8 0.0 0.091 12.0 0.0 1.3 1 0 0 1 1 1 0 Fibronectin-binding protein (FBP) VWA_2 PF13519.1 ETO05462.1 - 2e-05 24.7 0.0 4.2e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Sec23_trunk PF04811.10 ETO05462.1 - 6.9e-05 22.3 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain SprA-related PF12118.3 ETO05462.1 - 0.061 12.6 17.9 0.08 12.2 12.4 1.1 1 0 0 1 1 1 0 SprA-related family Daxx PF03344.10 ETO05462.1 - 0.77 8.1 21.7 1.1 7.6 15.1 1.1 1 0 0 1 1 1 0 Daxx Family Neur_chan_memb PF02932.11 ETO05462.1 - 1.2 8.9 10.6 1.9 8.3 7.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.2 ETO05462.1 - 2.9 5.4 22.0 3.8 5.0 15.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein WD40 PF00400.27 ETO05463.1 - 0.0026 17.5 0.1 0.0049 16.7 0.1 1.4 1 0 0 1 1 1 1 WD domain, G-beta repeat ECH PF00378.15 ETO05464.1 - 1.3e-27 96.5 0.4 1.6e-27 96.1 0.3 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Borrelia_orfA PF02414.10 ETO05464.1 - 0.023 13.8 0.5 0.036 13.1 0.3 1.3 1 0 0 1 1 1 0 Borrelia ORF-A WD40 PF00400.27 ETO05465.1 - 2.8e-50 166.4 16.7 2.3e-14 52.5 0.0 6.6 6 1 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 ETO05465.1 - 8.8e-08 32.0 0.1 0.00058 19.6 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO05465.1 - 2.3e-06 26.0 2.5 0.21 9.6 0.1 4.3 1 1 2 4 4 4 3 Nucleoporin Nup120/160 DUF1258 PF06869.7 ETO05465.1 - 0.00041 19.5 1.8 0.27 10.2 0.1 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF1258) PD40 PF07676.7 ETO05465.1 - 0.00077 19.0 1.9 13 5.5 0.0 4.8 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat BBS2_Mid PF14783.1 ETO05465.1 - 0.004 16.9 1.8 2.7 7.8 0.2 4.4 2 2 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Cytochrom_D1 PF02239.11 ETO05465.1 - 0.012 13.9 0.0 2.1 6.5 0.0 2.6 1 1 2 3 3 3 0 Cytochrome D1 heme domain DUF1973 PF09315.6 ETO05465.1 - 0.048 13.0 0.0 0.39 10.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1973) ABC_tran PF00005.22 ETO05467.1 - 0.0012 19.1 0.0 0.0013 19.0 0.0 1.5 1 1 0 1 1 1 1 ABC transporter DUF258 PF03193.11 ETO05467.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PVL_ORF50 PF07768.6 ETO05468.1 - 0.31 11.0 4.9 1 9.3 0.5 2.4 2 0 0 2 2 2 0 PVL ORF-50-like family JmjC PF02373.17 ETO05468.1 - 4.2 7.6 6.9 5.9 7.1 1.7 2.4 2 1 0 2 2 2 0 JmjC domain, hydroxylase TraG-D_C PF12696.2 ETO05469.1 - 1.4 8.7 6.4 2.2 8.1 4.4 1.4 1 1 0 1 1 1 0 TraM recognition site of TraD and TraG Peptidase_S49_N PF08496.5 ETO05469.1 - 8.6 6.1 10.2 11 5.7 7.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal EF-hand_4 PF12763.2 ETO05470.1 - 3.2e-16 58.9 0.1 1e-15 57.3 0.0 1.9 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 ETO05470.1 - 9.9e-05 21.3 0.9 0.00031 19.8 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 ETO05470.1 - 0.0046 16.5 0.5 0.031 13.8 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 ETO05470.1 - 0.014 15.5 0.1 0.061 13.4 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair 2OG-FeII_Oxy_3 PF13640.1 ETO05471.1 - 4.4e-20 72.0 0.0 9.5e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 ETO05471.1 - 9.4e-05 21.9 0.3 0.00051 19.6 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 ETO05471.1 - 9.8e-05 22.5 0.0 0.00027 21.1 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily BCL_N PF04714.8 ETO05471.1 - 0.011 15.3 0.1 0.035 13.6 0.0 1.9 1 0 0 1 1 1 0 BCL7, N-terminal conserver region 2OG-FeII_Oxy_5 PF13759.1 ETO05471.1 - 0.035 14.4 2.8 0.061 13.6 0.0 2.6 3 0 0 3 3 3 0 Putative 2OG-Fe(II) oxygenase Mgr1 PF08602.5 ETO05472.1 - 0.038 13.0 2.4 0.055 12.4 1.7 1.3 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit Flexi_CP PF00286.15 ETO05472.1 - 0.16 11.6 0.4 0.36 10.5 0.1 1.7 2 0 0 2 2 2 0 Viral coat protein V_ATPase_I PF01496.14 ETO05472.1 - 0.23 9.2 7.2 0.29 8.9 5.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 ETO05472.1 - 0.75 8.1 10.3 1.1 7.5 7.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3287 PF11690.3 ETO05472.1 - 1.9 8.5 5.5 5.2 7.1 3.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3287) Nop53 PF07767.6 ETO05473.1 - 0.26 10.2 28.6 0.32 9.9 19.8 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) TFIIF_alpha PF05793.7 ETO05473.1 - 0.83 7.9 37.5 1.4 7.2 26.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4604 PF15377.1 ETO05473.1 - 1.3 9.2 30.8 1.8 8.7 21.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Nop14 PF04147.7 ETO05473.1 - 1.7 6.4 36.7 2.1 6.1 25.4 1.0 1 0 0 1 1 1 0 Nop14-like family SUZ PF12752.2 ETO05473.1 - 1.9 9.0 21.3 0.15 12.6 7.2 2.7 1 1 1 2 2 2 0 SUZ domain DUF1510 PF07423.6 ETO05473.1 - 9.3 5.5 36.5 10 5.4 25.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) GAGA_bind PF06217.7 ETO05474.1 - 0.037 14.0 17.4 0.045 13.7 12.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family CAF-1_p150 PF11600.3 ETO05474.1 - 0.18 11.1 27.1 0.0078 15.6 15.0 1.5 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1682 PF07946.9 ETO05474.1 - 0.24 10.2 10.8 0.33 9.7 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PAP2 PF01569.16 ETO05475.1 - 0.037 13.6 0.4 0.072 12.7 0.0 1.6 2 0 0 2 2 2 0 PAP2 superfamily DUF2628 PF10947.3 ETO05475.1 - 0.1 12.4 1.9 0.63 9.8 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2628) RNase_P_Rpp14 PF01900.14 ETO05476.1 - 6.6e-05 22.7 0.1 8.5e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Rpp14/Pop5 family RGS PF00615.14 ETO05477.1 - 0.0039 17.2 0.2 2.4 8.2 0.0 3.0 2 0 0 2 2 2 2 Regulator of G protein signaling domain B56 PF01603.15 ETO05479.1 - 5.5e-10 38.4 0.9 1.1e-09 37.4 0.6 1.5 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) B56 PF01603.15 ETO05480.1 - 1.3e-39 136.0 1.9 5e-39 134.0 1.3 1.7 1 1 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Vac14_Fab1_bd PF12755.2 ETO05480.1 - 0.11 12.8 0.7 0.98 9.8 0.4 2.4 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region FANCI_S2 PF14676.1 ETO05480.1 - 0.61 9.9 3.1 1.1 9.1 0.3 2.3 2 1 0 2 2 2 0 FANCI solenoid 2 DUF2045 PF09741.4 ETO05481.1 - 0.0014 17.7 0.2 0.0018 17.4 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2045) EBV-NA3 PF05009.7 ETO05482.1 - 0.3 10.3 4.6 0.38 9.9 3.2 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) NARP1 PF12569.3 ETO05482.1 - 0.73 8.5 7.2 0.87 8.2 5.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SGT1 PF07093.6 ETO05482.1 - 0.81 7.9 11.7 0.9 7.8 8.1 1.1 1 0 0 1 1 1 0 SGT1 protein DUF1510 PF07423.6 ETO05482.1 - 1.3 8.3 14.9 0.28 10.4 8.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 ETO05482.1 - 2.3 6.1 11.6 2.2 6.1 8.0 1.2 1 0 0 1 1 1 0 CDC45-like protein GRP PF07172.6 ETO05482.1 - 2.8 8.4 4.5 2.2 8.8 0.7 2.3 1 1 1 2 2 2 0 Glycine rich protein family RRN3 PF05327.6 ETO05482.1 - 4.1 5.3 7.5 4 5.4 5.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sporozoite_P67 PF05642.6 ETO05482.1 - 5.1 4.8 8.7 5.6 4.7 6.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SNAPc19 PF15497.1 ETO05483.1 - 0.039 14.1 1.0 0.039 14.1 0.7 1.8 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 DUF2072 PF09845.4 ETO05483.1 - 0.31 10.9 3.0 0.14 12.0 0.4 1.7 1 1 1 2 2 2 0 Zn-ribbon containing protein (DUF2072) Rgp1 PF08737.5 ETO05483.1 - 0.41 9.6 5.2 0.48 9.4 3.6 1.1 1 0 0 1 1 1 0 Rgp1 RasGEF PF00617.14 ETO05485.1 - 8.1e-17 61.5 0.8 1.4e-16 60.8 0.5 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF PF00617.14 ETO05486.1 - 1.5e-05 24.8 0.2 2.1e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain Trehalose_PPase PF02358.11 ETO05487.1 - 1.6e-36 125.4 0.0 9.3e-30 103.2 0.0 2.2 1 1 0 2 2 2 2 Trehalose-phosphatase CobT PF06213.7 ETO05487.1 - 0.0015 17.7 9.8 0.0015 17.7 6.8 1.5 2 0 0 2 2 1 1 Cobalamin biosynthesis protein CobT U79_P34 PF03064.11 ETO05487.1 - 0.035 13.6 7.7 0.32 10.5 6.2 1.8 2 0 0 2 2 2 0 HSV U79 / HCMV P34 DUF2722 PF10846.3 ETO05487.1 - 0.26 10.2 17.5 1.8 7.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DDHD PF02862.12 ETO05487.1 - 0.33 10.7 7.4 0.23 11.2 2.5 2.1 2 0 0 2 2 2 0 DDHD domain Vfa1 PF08432.5 ETO05487.1 - 0.47 10.4 19.3 0.076 13.0 9.5 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Afi1 PF07792.7 ETO05487.1 - 0.53 10.2 11.9 0.53 10.2 4.3 2.6 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF3449 PF11931.3 ETO05487.1 - 0.64 9.4 16.5 5.2 6.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) CDC45 PF02724.9 ETO05487.1 - 1.1 7.2 16.0 0.087 10.8 7.6 1.7 2 0 0 2 2 2 0 CDC45-like protein Peptidase_S49_N PF08496.5 ETO05487.1 - 1.6 8.5 7.9 3.1 7.5 3.4 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Suf PF05843.9 ETO05487.1 - 1.7 8.3 13.0 0.51 10.0 1.6 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) SprA-related PF12118.3 ETO05487.1 - 2.6 7.3 19.9 0.098 11.9 4.1 2.1 2 0 0 2 2 2 0 SprA-related family DUF1510 PF07423.6 ETO05487.1 - 3.5 6.9 24.1 0.26 10.6 12.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) TP53IP5 PF15331.1 ETO05487.1 - 3.5 7.4 11.6 0.56 10.0 3.7 2.2 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 TRAP_alpha PF03896.11 ETO05487.1 - 4.9 6.0 9.0 8.3 5.3 6.2 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SeqA PF03925.8 ETO05487.1 - 5.9 6.5 9.3 3.8 7.1 2.0 2.2 2 0 0 2 2 2 0 SeqA protein Tim54 PF11711.3 ETO05487.1 - 7.7 4.9 11.3 0.45 9.0 3.8 1.7 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 FLO_LFY PF01698.11 ETO05487.1 - 8.3 5.1 11.2 9.5 4.9 6.0 1.9 2 0 0 2 2 2 0 Floricaula / Leafy protein RP-C_C PF11800.3 ETO05487.1 - 8.5 6.0 9.6 2.2 7.9 3.2 2.0 2 0 0 2 2 2 0 Replication protein C C-terminal region CorA PF01544.13 ETO05489.1 - 2.7e-25 88.9 11.7 1.1e-17 64.0 2.2 3.0 2 1 1 3 3 3 2 CorA-like Mg2+ transporter protein YiaAB PF05360.9 ETO05489.1 - 0.071 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 yiaA/B two helix domain RE_TdeIII PF09520.5 ETO05490.1 - 0.45 9.7 9.2 0.48 9.6 6.4 1.0 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII zf-C3HC4_3 PF13920.1 ETO05491.1 - 7.2e-05 22.3 7.6 0.00011 21.7 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF3284 PF11687.3 ETO05491.1 - 0.043 13.5 3.7 0.067 12.9 2.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3284) EDR1 PF14381.1 ETO05492.1 - 0.038 13.5 0.1 6.9 6.1 0.0 2.2 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 PC_rep PF01851.17 ETO05494.1 - 2e-17 62.3 10.1 0.00014 21.9 0.2 7.1 8 0 0 8 8 8 3 Proteasome/cyclosome repeat HEAT_2 PF13646.1 ETO05494.1 - 0.075 13.3 0.6 0.82 9.9 0.0 3.1 4 0 0 4 4 4 0 HEAT repeats DUF1406 PF07190.6 ETO05496.1 - 0.026 14.2 1.4 1.9 8.1 0.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1406) WD40 PF00400.27 ETO05497.1 - 5.1e-79 257.5 15.4 3.9e-12 45.5 0.1 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO05497.1 - 1.5e-09 36.5 4.1 0.01 14.0 0.0 5.1 1 1 3 4 4 4 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO05497.1 - 1.7e-07 30.9 0.1 0.0035 16.8 0.0 2.4 1 1 1 2 2 2 2 PQQ-like domain Kelch_6 PF13964.1 ETO05497.1 - 3.1e-07 30.2 8.5 0.67 10.2 0.0 7.3 6 2 1 7 7 7 3 Kelch motif Cytochrom_D1 PF02239.11 ETO05497.1 - 6.5e-07 27.9 3.3 7.3e-05 21.2 0.2 3.2 2 1 1 3 3 3 2 Cytochrome D1 heme domain Kelch_5 PF13854.1 ETO05497.1 - 0.00089 19.1 2.3 6.2 6.8 0.0 5.1 5 0 0 5 5 5 1 Kelch motif Ricin_B_lectin PF00652.17 ETO05497.1 - 0.0064 16.5 1.8 0.17 11.9 0.1 3.4 1 1 1 3 3 3 1 Ricin-type beta-trefoil lectin domain Kelch_4 PF13418.1 ETO05497.1 - 0.013 15.2 6.5 0.31 10.8 0.0 4.7 6 1 1 7 7 7 0 Galactose oxidase, central domain Hira PF07569.6 ETO05497.1 - 0.065 12.4 3.2 12 5.0 0.0 3.9 4 1 1 5 5 5 0 TUP1-like enhancer of split Kelch_1 PF01344.20 ETO05497.1 - 0.067 12.7 7.7 5.5 6.6 0.6 4.3 4 0 0 4 4 4 0 Kelch motif PD40 PF07676.7 ETO05497.1 - 5.8 6.7 10.4 16 5.3 0.1 4.8 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat zf-C2H2_4 PF13894.1 ETO05498.1 - 3.9e-17 61.2 24.4 0.00031 20.8 0.3 5.6 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2 PF00096.21 ETO05498.1 - 6.9e-11 41.8 32.4 1.4e-05 25.1 0.9 6.4 5 1 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 ETO05498.1 - 0.0033 17.5 22.6 0.2 11.8 0.1 5.2 4 1 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 ETO05498.1 - 0.0078 16.4 0.3 0.0078 16.4 0.2 7.0 7 1 0 7 7 7 2 Zinc-finger double domain PRK PF00485.13 ETO05498.1 - 0.038 13.5 0.0 0.085 12.4 0.0 1.6 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family zf-BED PF02892.10 ETO05498.1 - 0.19 11.4 14.2 0.99 9.2 2.2 3.3 3 0 0 3 3 3 0 BED zinc finger zf-H2C2_5 PF13909.1 ETO05498.1 - 0.38 11.0 17.2 3.8 7.9 0.3 5.3 5 1 0 5 5 5 0 C2H2-type zinc-finger domain zf-Di19 PF05605.7 ETO05498.1 - 1 9.5 16.0 1.5 9.0 0.1 4.1 4 1 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 ETO05498.1 - 1.8 8.8 28.8 2.5 8.4 0.2 6.1 7 0 0 7 7 6 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 ETO05498.1 - 3.5 7.3 7.3 6.8 6.4 1.0 3.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF629 PF04780.7 ETO05498.1 - 4 5.8 14.2 0.88 8.0 3.7 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.2 ETO05498.1 - 4.8 7.3 21.2 3.2 7.9 4.2 3.5 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) DZR PF12773.2 ETO05498.1 - 8.3 6.3 11.1 1.1 9.1 0.3 3.2 2 2 0 2 2 2 0 Double zinc ribbon zf-C2H2_6 PF13912.1 ETO05498.1 - 9.2 6.3 12.6 2.4 8.1 0.9 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger TPR_12 PF13424.1 ETO05499.1 - 4.3e-115 375.8 25.4 1.6e-24 85.6 0.1 7.0 5 1 0 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETO05499.1 - 4.7e-75 244.3 65.2 2.6e-11 42.6 1.6 11.6 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_11 PF13414.1 ETO05499.1 - 6.8e-69 227.4 37.9 6.4e-19 67.3 1.2 7.6 4 2 1 7 7 7 7 TPR repeat TPR_10 PF13374.1 ETO05499.1 - 6.7e-68 222.8 0.0 9.1e-09 34.9 0.0 10.6 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_2 PF07719.12 ETO05499.1 - 1.4e-59 193.2 51.5 4.1e-08 32.5 0.8 11.7 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_7 PF13176.1 ETO05499.1 - 9.2e-53 171.9 23.1 4.2e-07 29.2 0.1 11.4 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_8 PF13181.1 ETO05499.1 - 4e-47 154.4 67.8 2.3e-07 30.1 2.6 11.9 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_17 PF13431.1 ETO05499.1 - 7.1e-28 94.4 28.9 0.00098 19.1 0.1 11.3 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_16 PF13432.1 ETO05499.1 - 7.7e-27 93.3 2.6 1.4e-08 35.1 0.0 7.1 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.1 ETO05499.1 - 1.8e-22 78.1 16.5 0.0012 19.1 0.0 12.1 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO05499.1 - 1.2e-19 69.0 0.0 0.66 10.7 0.0 10.5 9 1 0 10 10 10 3 Tetratricopeptide repeat Apc3 PF12895.2 ETO05499.1 - 2.5e-13 49.9 33.7 3.9e-05 23.7 1.2 6.5 1 1 6 7 7 7 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO05499.1 - 7e-12 45.5 11.4 0.012 15.9 0.3 8.0 5 3 5 10 10 9 5 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO05499.1 - 1.9e-09 36.5 8.5 0.014 14.5 0.0 6.9 7 0 0 7 7 7 3 SHNi-TPR MIT PF04212.13 ETO05499.1 - 1.6e-07 31.0 29.2 1.4 8.8 0.3 9.8 10 0 0 10 10 10 3 MIT (microtubule interacting and transport) domain PPR PF01535.15 ETO05499.1 - 3.2e-07 29.8 25.3 0.03 14.3 0.0 9.4 11 0 0 11 11 10 2 PPR repeat TPR_3 PF07720.7 ETO05499.1 - 5.4e-07 29.2 57.5 0.005 16.6 0.3 9.3 9 0 0 9 9 9 3 Tetratricopeptide repeat PPR_2 PF13041.1 ETO05499.1 - 0.1 12.5 17.2 2.6 8.0 0.1 7.0 7 0 0 7 7 7 0 PPR repeat family WD40 PF00400.27 ETO05500.1 - 1.2e-53 177.1 20.3 5.7e-12 45.0 0.2 7.0 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO05500.1 - 4.2e-13 48.2 1.5 0.016 13.3 0.1 5.0 3 2 2 5 5 5 5 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO05502.1 - 7.9e-06 26.1 0.6 7.9e-06 26.1 0.4 2.7 2 2 1 3 3 3 1 TRAF-type zinc finger DUF972 PF06156.8 ETO05502.1 - 0.0013 19.0 23.2 0.3 11.4 5.5 3.0 1 1 1 2 2 2 2 Protein of unknown function (DUF972) Scaffolding_pro PF11418.3 ETO05502.1 - 1 9.7 15.0 0.061 13.6 5.4 2.5 1 1 1 2 2 2 0 Phi29 scaffolding protein Acetyltransf_11 PF13720.1 ETO05502.1 - 1.1 9.5 6.2 1.9 8.7 0.1 2.9 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 JmjC PF02373.17 ETO05503.1 - 1.7e-16 60.4 1.8 1.7e-16 60.4 1.2 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 ETO05503.1 - 6.2e-08 32.4 1.4 1.2e-07 31.5 1.0 1.4 1 0 0 1 1 1 1 Cupin-like domain Channel_Tsx PF03502.8 ETO05503.1 - 0.0021 17.8 0.4 0.0033 17.2 0.3 1.3 1 0 0 1 1 1 1 Nucleoside-specific channel-forming protein, Tsx UBA_4 PF14555.1 ETO05503.1 - 0.11 12.0 0.3 0.4 10.2 0.2 1.9 2 0 0 2 2 2 0 UBA-like domain Myticin-prepro PF10690.4 ETO05504.1 - 0.02 14.9 4.1 0.095 12.7 0.3 2.1 1 1 1 2 2 2 0 Myticin pre-proprotein from the mussel Lipase_3 PF01764.20 ETO05505.1 - 0.00027 20.5 0.0 0.00048 19.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF3439 PF11921.3 ETO05505.1 - 0.0016 18.1 1.5 0.0027 17.4 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 ETO05505.1 - 0.056 11.2 1.0 0.067 10.9 0.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SMN PF06003.7 ETO05505.1 - 0.1 11.6 2.4 0.15 11.1 1.7 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Mito_fiss_reg PF05308.6 ETO05505.1 - 6.7 5.9 21.6 1.4 8.2 6.6 2.1 1 1 1 2 2 2 0 Mitochondrial fission regulator DUF724 PF05266.9 ETO05506.1 - 0.5 9.9 14.5 0.54 9.8 10.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Sec62 PF03839.11 ETO05506.1 - 0.92 8.8 13.8 1.1 8.6 9.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF262 PF03235.9 ETO05506.1 - 0.94 9.4 4.2 1 9.2 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 DUF1703 PF08011.6 ETO05506.1 - 1.7 8.4 14.5 2.6 7.8 10.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1703) MFS_Mycoplasma PF07672.8 ETO05506.1 - 1.7 7.7 4.8 2 7.5 3.3 1.3 1 0 0 1 1 1 0 Mycoplasma MFS transporter PvlArgDC PF01862.11 ETO05506.1 - 6.9 6.2 5.9 8.4 5.9 4.1 1.1 1 0 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) RR_TM4-6 PF06459.7 ETO05506.1 - 7.1 6.4 9.8 7.5 6.3 6.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 WD40 PF00400.27 ETO05507.1 - 4.4e-70 229.2 15.5 5.4e-13 48.2 0.0 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO05507.1 - 7e-12 44.2 0.8 0.0063 14.7 0.1 4.9 2 1 2 4 4 4 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO05507.1 - 2.1e-06 27.3 0.0 1.1e-05 25.0 0.0 2.1 1 1 1 2 2 2 2 PQQ-like domain Cytochrom_D1 PF02239.11 ETO05507.1 - 2.5e-06 26.0 0.3 0.0002 19.7 0.0 2.5 1 1 0 2 2 2 1 Cytochrome D1 heme domain PD40 PF07676.7 ETO05507.1 - 8.5e-05 22.1 2.5 4.7 6.9 0.0 5.0 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO05507.1 - 0.00044 19.1 4.9 0.94 8.1 0.1 4.2 1 1 3 4 4 4 3 Nup133 N terminal like TolB_N PF04052.8 ETO05507.1 - 0.0037 17.3 0.0 3.4 7.7 0.0 3.2 3 1 0 3 3 3 1 TolB amino-terminal domain Hira PF07569.6 ETO05507.1 - 0.0038 16.4 0.3 2.8 7.1 0.0 3.9 2 2 3 5 5 5 1 TUP1-like enhancer of split PQQ PF01011.16 ETO05507.1 - 0.048 13.2 0.0 15 5.3 0.0 3.6 4 0 0 4 4 4 0 PQQ enzyme repeat Resistin PF06954.6 ETO05507.1 - 0.059 13.6 4.4 19 5.5 0.1 3.8 2 2 2 4 4 4 0 Resistin Antimicrobial_7 PF08102.6 ETO05507.1 - 0.074 13.0 0.5 0.43 10.6 0.1 2.5 2 0 0 2 2 2 0 Scorpion antimicrobial peptide S10_plectin PF03501.10 ETO05508.1 - 1.8e-18 66.1 0.8 2.6e-18 65.6 0.6 1.2 1 0 0 1 1 1 1 Plectin/S10 domain Homeobox_KN PF05920.6 ETO05509.1 - 3.2e-13 49.1 0.5 3.2e-13 49.1 0.3 2.1 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 ETO05509.1 - 6.1e-10 38.5 1.4 1.5e-09 37.2 1.0 1.7 1 0 0 1 1 1 1 Homeobox domain Gly-rich_Ago1 PF12764.2 ETO05509.1 - 4.8 7.8 9.5 0.19 12.3 0.2 3.0 2 1 1 3 3 3 0 Glycine-rich region of argonaut GMC_oxred_C PF05199.8 ETO05511.1 - 0.0018 18.5 0.0 0.0023 18.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase Myb_CC_LHEQLE PF14379.1 ETO05511.1 - 0.034 13.7 1.7 0.053 13.0 1.1 1.3 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif DivIC PF04977.10 ETO05511.1 - 0.22 11.0 3.2 0.38 10.2 2.2 1.3 1 0 0 1 1 1 0 Septum formation initiator Hom_end_hint PF05203.11 ETO05511.1 - 0.25 11.0 0.9 0.39 10.4 0.0 1.6 2 0 0 2 2 2 0 Hom_end-associated Hint PGM_PMM_I PF02878.11 ETO05512.1 - 2.2e-35 121.1 0.5 2.3e-31 108.1 0.1 2.6 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 ETO05512.1 - 1.3e-18 67.1 0.0 6.3e-15 55.3 0.0 2.7 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 ETO05512.1 - 1.5e-05 24.9 0.0 4.3e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III BOFC_N PF08977.5 ETO05512.1 - 0.43 10.4 2.2 0.5 10.2 0.1 2.1 2 1 1 3 3 3 0 Bypass of Forespore C, N terminal Kelch_6 PF13964.1 ETO05513.1 - 5.6e-06 26.2 8.3 0.36 11.0 0.1 4.7 3 1 1 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO05513.1 - 0.00043 20.1 3.9 0.27 11.2 0.3 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 ETO05513.1 - 0.00099 18.6 8.8 0.056 12.9 0.2 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO05513.1 - 0.0019 18.3 0.1 3.1 8.0 0.0 3.8 3 0 0 3 3 3 1 Galactose oxidase, central domain N_Asn_amidohyd PF14736.1 ETO05513.1 - 0.037 12.9 0.1 5.4 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein N-terminal asparagine amidohydrolase DUF497 PF04365.8 ETO05513.1 - 0.098 12.5 0.6 0.46 10.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF497) WD40 PF00400.27 ETO05514.1 - 2.1e-40 135.1 17.8 9.5e-12 44.3 0.4 6.0 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO05514.1 - 2e-09 36.1 5.0 0.00095 17.4 0.1 4.1 2 1 2 4 4 4 4 Nucleoporin Nup120/160 BOP1NT PF08145.7 ETO05515.1 - 2e-47 162.1 1.2 2e-47 162.1 0.8 1.8 2 0 0 2 2 2 1 BOP1NT (NUC169) domain WD40 PF00400.27 ETO05515.1 - 3.5e-27 93.2 17.8 1.8e-12 46.6 0.6 7.4 8 0 0 8 8 8 4 WD domain, G-beta repeat YlbD_coat PF14071.1 ETO05516.1 - 2.8 8.0 8.1 20 5.2 0.0 4.4 5 0 0 5 5 5 0 Putative coat protein Redoxin PF08534.5 ETO05517.1 - 0.1 12.1 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Redoxin Tox-ART-HYE1 PF15634.1 ETO05517.1 - 0.16 10.9 4.0 0.17 10.8 2.8 1.0 1 0 0 1 1 1 0 HYE1 signature containing ADP-ribosyltransferase RRP7 PF12923.2 ETO05518.1 - 0.14 12.1 2.9 0.28 11.2 0.1 2.2 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) DivIC PF04977.10 ETO05520.1 - 2.1e-05 23.9 1.8 2.1e-05 23.9 1.3 3.2 4 0 0 4 4 4 1 Septum formation initiator CDC45 PF02724.9 ETO05520.1 - 0.92 7.4 11.7 0.0069 14.4 2.3 1.7 2 0 0 2 2 2 0 CDC45-like protein Zip PF02535.17 ETO05520.1 - 3 6.7 11.6 1.6 7.6 5.5 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Plasmodium_Vir PF05795.6 ETO05520.1 - 6.5 5.8 12.7 0.14 11.3 3.3 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein WD40 PF00400.27 ETO05522.1 - 1.1e-84 275.6 24.4 4.4e-13 48.5 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO05522.1 - 2.6e-10 40.3 0.1 0.00018 21.2 0.1 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO05522.1 - 5.3e-09 34.7 6.9 0.016 13.3 0.0 5.1 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO05522.1 - 2.3e-08 32.7 1.1 0.0002 19.8 0.1 2.8 2 1 1 3 3 3 2 Cytochrome D1 heme domain DUF1258 PF06869.7 ETO05522.1 - 0.00012 21.2 4.5 0.34 9.9 0.1 4.6 1 1 5 6 6 6 1 Protein of unknown function (DUF1258) Resistin PF06954.6 ETO05522.1 - 0.00067 19.8 0.2 5.9 7.2 0.0 4.0 3 1 1 4 4 4 1 Resistin Nbas_N PF15492.1 ETO05522.1 - 0.0073 15.4 2.4 11 5.0 0.1 4.1 1 1 2 5 5 5 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 ETO05522.1 - 0.019 14.6 4.0 2.6 7.8 0.0 4.7 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 ETO05522.1 - 0.025 13.1 0.3 10 4.5 0.0 3.5 1 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Pneumovirus_M2 PF06436.6 ETO05522.1 - 0.051 12.7 1.3 0.1 11.8 0.9 1.4 1 0 0 1 1 1 0 Pneumovirus matrix protein 2 (M2) PORR PF11955.3 ETO05522.1 - 0.065 11.9 0.0 0.086 11.5 0.0 1.1 1 0 0 1 1 1 0 Plant organelle RNA recognition domain zf-TRAF PF02176.13 ETO05524.1 - 1.7e-05 25.1 2.6 4.2e-05 23.8 1.0 2.3 1 1 0 1 1 1 1 TRAF-type zinc finger Fzo_mitofusin PF04799.8 ETO05524.1 - 0.064 12.6 3.0 0.087 12.2 0.6 2.0 2 0 0 2 2 2 0 fzo-like conserved region zf-C3HC4_2 PF13923.1 ETO05524.1 - 7.5 6.6 15.4 0.42 10.6 2.9 3.7 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.15 ETO05524.1 - 8.4 5.9 11.9 0.11 11.9 1.5 2.8 4 0 0 4 4 4 0 MIZ/SP-RING zinc finger EMP24_GP25L PF01105.19 ETO05526.1 - 0.028 14.1 1.0 0.028 14.1 0.7 1.7 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD ecTbetaR2 PF08917.5 ETO05526.1 - 0.086 12.6 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Transforming growth factor beta receptor 2 ectodomain DUF2883 PF11097.3 ETO05526.1 - 0.1 12.7 0.2 0.55 10.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2883) bZIP_1 PF00170.16 ETO05526.1 - 0.19 11.7 2.9 0.3 11.0 0.6 2.2 2 0 0 2 2 2 0 bZIP transcription factor Fzo_mitofusin PF04799.8 ETO05526.1 - 0.21 10.9 2.6 0.47 9.8 1.8 1.6 1 0 0 1 1 1 0 fzo-like conserved region DUF972 PF06156.8 ETO05526.1 - 0.39 11.0 3.8 0.33 11.3 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 ETO05526.1 - 0.46 10.0 3.0 0.72 9.4 2.1 1.3 1 0 0 1 1 1 0 IncA protein Ly49 PF08391.5 ETO05526.1 - 0.58 10.3 4.3 0.7 10.0 0.5 2.2 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region WD40 PF00400.27 ETO05527.1 - 6.4e-59 193.8 17.1 8e-11 41.3 0.3 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO05527.1 - 3.1e-14 52.0 3.2 6.3e-05 21.2 0.1 5.2 2 2 2 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO05527.1 - 0.00019 20.3 12.1 0.28 9.8 0.2 4.2 2 1 2 5 5 5 3 Nup133 N terminal like EF-hand_1 PF00036.27 ETO05528.1 - 7.4e-24 81.2 15.1 4.8e-07 28.6 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 ETO05528.1 - 2.1e-22 79.0 11.9 6.2e-14 51.8 2.2 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO05528.1 - 3.8e-19 66.7 10.2 7e-05 22.3 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 ETO05528.1 - 5.2e-15 54.0 12.4 7e-05 21.9 0.2 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 ETO05528.1 - 1.1e-13 50.5 16.0 1.1e-08 34.5 1.0 3.8 1 1 3 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 ETO05528.1 - 0.0037 17.2 5.6 0.086 12.8 0.1 3.0 3 0 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 ETO05528.1 - 0.11 12.1 3.8 5.8 6.6 0.6 4.1 3 1 1 4 4 4 0 EF hand DUF2272 PF10030.4 ETO05529.1 - 7.5e-05 22.2 0.0 0.15 11.5 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2272) Kelch_4 PF13418.1 ETO05529.1 - 0.0077 15.9 0.0 6.8 6.5 0.0 3.0 2 0 0 2 2 2 2 Galactose oxidase, central domain WD40 PF00400.27 ETO05530.1 - 2.5e-35 119.0 5.9 3.5e-12 45.7 0.0 4.0 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO05530.1 - 2.9e-06 25.7 0.8 0.0027 15.8 0.6 2.2 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO05530.1 - 0.002 16.9 2.5 0.74 8.4 0.1 2.9 1 1 1 2 2 2 2 Nup133 N terminal like Ricin_B_lectin PF00652.17 ETO05530.1 - 0.029 14.3 2.1 0.049 13.6 1.2 1.5 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain DUF884 PF05959.6 ETO05530.1 - 0.059 12.6 0.1 0.12 11.6 0.0 1.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF884) Bet_v_1 PF00407.14 ETO05530.1 - 0.58 9.7 2.7 1.6 8.3 0.2 2.4 1 1 1 2 2 2 0 Pathogenesis-related protein Bet v I family WD40 PF00400.27 ETO05531.1 - 2.1e-28 97.1 13.2 4.6e-12 45.3 0.2 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO05531.1 - 6.3e-06 24.6 3.7 0.0036 15.5 0.8 3.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Marek_SORF3 PF07153.6 ETO05531.1 - 0.023 13.3 0.1 0.035 12.7 0.0 1.2 1 0 0 1 1 1 0 Marek's disease-like virus SORF3 protein Nucleoporin_N PF08801.6 ETO05531.1 - 0.12 11.0 6.5 0.66 8.6 0.0 2.3 1 1 0 2 2 2 0 Nup133 N terminal like WD40 PF00400.27 ETO05532.1 - 2e-65 214.4 18.6 1.1e-12 47.3 0.1 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO05532.1 - 7.5e-11 40.8 2.6 0.045 11.8 0.0 5.8 3 2 3 6 6 6 5 Nucleoporin Nup120/160 DUF1900 PF08954.6 ETO05532.1 - 0.01 15.3 0.4 7 6.1 0.0 3.5 4 1 1 5 5 5 0 Domain of unknown function (DUF1900) Methyltransf_25 PF13649.1 ETO05532.1 - 0.029 14.7 0.1 5.4 7.4 0.0 3.1 3 1 1 4 4 4 0 Methyltransferase domain PQQ_2 PF13360.1 ETO05532.1 - 0.16 11.4 0.7 23 4.3 0.0 3.0 2 2 2 4 4 4 0 PQQ-like domain HR1 PF02185.11 ETO05533.1 - 0.0067 16.1 6.1 0.025 14.3 0.5 2.3 2 0 0 2 2 2 2 Hr1 repeat Sds3 PF08598.6 ETO05533.1 - 0.11 11.9 5.4 0.53 9.7 0.3 2.2 1 1 1 2 2 2 0 Sds3-like Prefoldin_2 PF01920.15 ETO05533.1 - 0.19 11.5 7.4 1.1 9.0 1.1 2.3 2 0 0 2 2 2 0 Prefoldin subunit Tup_N PF08581.5 ETO05533.1 - 0.26 11.5 3.9 3.2 7.9 0.3 2.4 2 0 0 2 2 2 0 Tup N-terminal Med4 PF10018.4 ETO05533.1 - 1.2 8.4 6.7 0.77 9.1 0.3 2.1 1 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 BCS1_N PF08740.6 ETO05534.1 - 0.21 11.2 3.9 0.32 10.6 2.7 1.4 1 1 0 1 1 1 0 BCS1 N terminal RNA_pol_Rpb1_5 PF04998.12 ETO05534.1 - 0.78 8.9 4.8 0.89 8.7 3.3 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 zf-C3HC4_2 PF13923.1 ETO05535.1 - 0.0004 20.3 0.9 0.0026 17.7 0.6 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO05535.1 - 0.0028 17.4 0.6 0.0077 16.0 0.4 1.7 1 1 0 1 1 1 1 Ring finger domain DUF1644 PF07800.7 ETO05535.1 - 0.013 15.3 2.9 0.023 14.5 2.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) zf-RING-like PF08746.6 ETO05535.1 - 0.78 9.7 5.2 2.6 8.1 3.1 2.3 2 1 1 3 3 3 0 RING-like domain zf-C3HC4_3 PF13920.1 ETO05535.1 - 0.83 9.3 4.5 7.6 6.2 3.1 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MMR_HSR1 PF01926.18 ETO05536.1 - 2.5e-25 88.6 0.1 5.1e-25 87.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETO05536.1 - 5.5e-12 45.2 0.0 9.6e-12 44.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 ETO05536.1 - 3.1e-07 30.3 0.5 0.0084 15.9 0.0 2.8 3 0 0 3 3 3 2 Dynamin family Miro PF08477.8 ETO05536.1 - 4e-06 27.3 0.5 2.2e-05 24.9 0.1 2.4 2 1 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 ETO05536.1 - 1.7e-05 24.0 0.0 3.9e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 ETO05536.1 - 5.8e-05 22.2 0.0 9.5e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 AIG1 family AAA_17 PF13207.1 ETO05536.1 - 0.0004 21.1 0.1 0.0017 19.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 ETO05536.1 - 0.0012 18.6 0.0 0.0031 17.2 0.0 1.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.5 ETO05536.1 - 0.0016 17.6 0.0 0.0034 16.6 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 ETO05536.1 - 0.013 15.8 0.8 0.028 14.7 0.0 2.1 2 1 0 2 2 2 0 ABC transporter AAA_18 PF13238.1 ETO05536.1 - 0.014 15.7 0.1 0.056 13.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Glyco_hydro_65m PF03632.10 ETO05536.1 - 0.015 14.0 0.2 0.026 13.2 0.0 1.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 65 central catalytic domain FtsK_SpoIIIE PF01580.13 ETO05536.1 - 0.018 14.4 0.0 1.5 8.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family GTP_EFTU PF00009.22 ETO05536.1 - 0.032 13.6 0.1 1.8 7.9 0.0 3.2 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 ETO05536.1 - 0.047 13.8 0.0 0.15 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 ETO05536.1 - 0.053 13.2 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Archaeal ATPase Ras PF00071.17 ETO05536.1 - 0.065 12.6 0.0 0.19 11.1 0.0 1.9 2 0 0 2 2 2 0 Ras family AAA_29 PF13555.1 ETO05536.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 ETO05536.1 - 2.3 8.5 6.9 14 5.9 4.8 2.2 1 1 0 1 1 1 0 AAA domain Actin PF00022.14 ETO05537.1 - 9.1e-82 274.5 0.0 1.1e-81 274.3 0.0 1.0 1 0 0 1 1 1 1 Actin Actin PF00022.14 ETO05538.1 - 5.2e-25 87.6 0.0 6.7e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 Actin DUF3023 PF11224.3 ETO05538.1 - 0.034 13.7 0.3 0.27 10.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3023) ESSS PF10183.4 ETO05538.1 - 0.062 13.7 0.0 0.099 13.0 0.0 1.3 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Kelch_5 PF13854.1 ETO05539.1 - 0.14 12.1 1.2 1.6 8.7 0.0 3.2 3 1 1 4 4 4 0 Kelch motif BrkDBD PF09607.5 ETO05543.1 - 0.0091 15.5 1.4 0.61 9.6 0.3 2.8 2 0 0 2 2 2 1 Brinker DNA-binding domain FlxA PF14282.1 ETO05543.1 - 0.013 15.4 6.0 0.2 11.6 1.9 2.6 2 0 0 2 2 2 0 FlxA-like protein NPV_P10 PF05531.7 ETO05543.1 - 0.27 11.4 4.2 6.2 7.1 0.0 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Cys_knot PF00007.17 ETO05543.1 - 0.29 11.2 7.4 0.22 11.6 3.4 2.0 2 1 0 2 2 2 0 Cystine-knot domain CDC37_N PF03234.9 ETO05543.1 - 3.3 7.9 9.2 1.6 9.0 4.4 1.8 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding Apolipoprotein PF01442.13 ETO05544.1 - 0.00011 21.7 15.7 0.00016 21.2 10.9 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain UPF0118 PF01594.11 ETO05544.1 - 0.0034 16.4 3.6 0.0034 16.4 2.5 1.4 1 1 0 1 1 1 1 Domain of unknown function DUF20 Spc7 PF08317.6 ETO05544.1 - 0.056 12.0 23.8 0.077 11.6 16.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.4 ETO05544.1 - 0.12 11.3 17.9 0.18 10.7 12.4 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 NPV_P10 PF05531.7 ETO05544.1 - 0.35 11.1 18.2 1.5 9.1 4.9 2.8 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 ETO05544.1 - 0.75 9.3 16.2 1.2 8.6 11.2 1.4 1 0 0 1 1 1 0 IncA protein DUF3584 PF12128.3 ETO05544.1 - 0.95 6.7 22.0 1.2 6.3 15.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Tropomyosin_1 PF12718.2 ETO05544.1 - 1.1 9.0 21.9 3.6 7.4 15.2 1.8 1 1 0 1 1 1 0 Tropomyosin like Reo_sigmaC PF04582.7 ETO05544.1 - 1.2 8.2 6.5 0.92 8.6 3.0 1.5 1 1 0 1 1 1 0 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 ETO05544.1 - 3 7.7 31.6 4 7.3 8.6 3.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding FliT PF05400.8 ETO05544.1 - 3.6 8.0 10.7 38 4.7 6.1 2.8 1 1 1 2 2 2 0 Flagellar protein FliT Troponin PF00992.15 ETO05544.1 - 3.6 7.6 22.8 4.5 7.3 12.3 2.2 1 1 1 2 2 2 0 Troponin Toprim PF01751.17 ETO05544.1 - 6.5 6.7 9.0 1.6 8.7 3.0 2.2 1 1 1 2 2 2 0 Toprim domain Pkinase PF00069.20 ETO05545.1 - 1.7e-08 33.9 0.1 2.7e-08 33.2 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain DAG_kinase_N PF14513.1 ETO05545.1 - 0.0048 17.1 1.6 0.017 15.3 1.1 1.9 1 1 1 2 2 2 1 Diacylglycerol kinase N-terminus Peptidase_C14 PF00656.17 ETO05546.1 - 2.9e-13 50.0 0.8 3.7e-13 49.7 0.5 1.3 1 1 0 1 1 1 1 Caspase domain Guanylate_cyc_2 PF09778.4 ETO05546.1 - 0.044 12.9 0.2 0.067 12.3 0.1 1.3 1 0 0 1 1 1 0 Guanylylate cyclase WD40 PF00400.27 ETO05547.1 - 1.8e-19 68.8 0.1 1.5e-09 37.3 0.0 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO05547.1 - 0.0073 14.4 0.0 0.064 11.3 0.0 2.0 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO05547.1 - 0.019 13.7 1.9 0.61 8.7 0.2 2.5 2 1 0 2 2 2 0 Nup133 N terminal like RecU PF03838.9 ETO05548.1 - 0.1 12.1 0.5 1.1 8.7 0.0 2.2 1 1 1 2 2 2 0 Recombination protein U Sua5_yciO_yrdC PF01300.13 ETO05549.1 - 0.013 14.7 0.7 0.018 14.2 0.5 1.2 1 0 0 1 1 1 0 Telomere recombination Peptidase_M56 PF05569.6 ETO05549.1 - 0.036 13.0 0.2 0.059 12.3 0.1 1.3 1 1 0 1 1 1 0 BlaR1 peptidase M56 zf-C2H2_7 PF15269.1 ETO05552.1 - 0.15 11.9 0.4 0.31 10.9 0.0 1.7 2 0 0 2 2 2 0 Zinc-finger MatE PF01554.13 ETO05554.1 - 0.00028 20.5 16.2 0.0006 19.4 9.3 2.6 2 1 0 2 2 2 1 MatE Brevenin PF03032.10 ETO05554.1 - 0.13 12.1 1.6 0.38 10.6 1.1 1.8 1 0 0 1 1 1 0 Brevenin/esculentin/gaegurin/rugosin family WD40 PF00400.27 ETO05556.1 - 9.1e-33 110.9 6.1 2.7e-13 49.2 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO05556.1 - 3.8e-05 22.0 1.2 0.00027 19.2 0.8 2.3 1 1 0 1 1 1 1 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO05556.1 - 0.00073 19.0 0.6 0.32 10.3 0.1 2.1 1 1 1 2 2 2 2 PQQ-like domain PQQ PF01011.16 ETO05556.1 - 0.0082 15.6 0.0 0.67 9.6 0.0 3.5 3 1 1 4 4 4 1 PQQ enzyme repeat DPPIV_N PF00930.16 ETO05556.1 - 0.022 13.3 0.0 1.1 7.7 0.0 2.0 1 1 1 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Cytochrom_D1 PF02239.11 ETO05556.1 - 0.029 12.6 0.2 0.42 8.8 0.1 2.0 1 1 1 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.7 ETO05556.1 - 0.036 13.7 0.0 7.6 6.3 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 ETO05556.1 - 0.061 12.6 0.1 8.1 5.8 0.0 2.5 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature PQQ_3 PF13570.1 ETO05556.1 - 0.092 13.0 0.0 1.1 9.6 0.0 2.4 2 0 0 2 2 2 0 PQQ-like domain Nucleoporin_N PF08801.6 ETO05556.1 - 0.16 10.6 1.4 6.1 5.4 0.0 2.5 1 1 2 3 3 3 0 Nup133 N terminal like DIX PF00778.12 ETO05557.1 - 0.051 13.3 0.6 0.19 11.4 0.0 2.3 2 0 0 2 2 2 0 DIX domain YlqD PF11068.3 ETO05557.1 - 6.8 6.7 16.5 3.7 7.5 8.7 2.6 2 0 0 2 2 2 0 YlqD protein IncA PF04156.9 ETO05557.1 - 8 6.0 17.8 4.2 6.9 9.7 2.2 2 0 0 2 2 2 0 IncA protein APG6 PF04111.7 ETO05557.1 - 9.7 5.1 30.4 0.91 8.5 13.6 2.6 2 1 0 2 2 2 0 Autophagy protein Apg6 TPR_19 PF14559.1 ETO05558.1 - 1.2e-12 48.0 0.5 4.8e-06 26.8 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO05558.1 - 5.3e-08 32.8 0.0 0.1 13.3 0.0 5.6 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO05558.1 - 2.4e-06 27.0 1.9 0.092 12.4 0.0 4.9 5 1 1 6 6 6 2 TPR repeat TPR_2 PF07719.12 ETO05558.1 - 7.4e-05 22.3 4.0 13 5.9 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO05558.1 - 0.00017 21.8 2.3 10 6.8 0.0 6.0 7 0 0 7 7 6 1 Tetratricopeptide repeat Coatomer_E PF04733.9 ETO05558.1 - 0.00029 20.1 0.7 0.00062 19.0 0.0 1.8 2 0 0 2 2 2 1 Coatomer epsilon subunit Apc3 PF12895.2 ETO05558.1 - 0.0003 20.8 2.7 0.0029 17.6 0.0 3.5 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 ETO05558.1 - 0.00082 18.5 2.4 0.0028 16.7 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO05558.1 - 0.0011 19.6 0.1 3.2 8.5 0.0 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.4 ETO05558.1 - 0.0085 16.0 0.9 0.026 14.4 0.0 2.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.1 ETO05558.1 - 0.035 14.2 0.2 0.1 12.7 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETO05558.1 - 0.068 12.8 3.5 65 3.3 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 ETO05558.1 - 0.12 12.2 0.7 0.69 9.8 0.0 2.8 3 1 0 3 3 2 0 Tetratricopeptide repeat GST_C PF00043.20 ETO05559.1 - 1.3e-06 28.3 0.1 2.4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 ETO05559.1 - 0.00059 20.2 0.0 0.0012 19.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 ETO05559.1 - 0.0019 18.3 0.0 0.0036 17.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 ETO05559.1 - 0.014 15.3 0.0 0.023 14.5 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PapG_N PF03627.8 ETO05560.1 - 0.0053 16.2 0.2 0.0053 16.2 0.1 1.1 1 0 0 1 1 1 1 PapG carbohydrate binding domain DUF4028 PF13220.1 ETO05560.1 - 0.13 11.9 0.6 16 5.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4028) DUF1510 PF07423.6 ETO05561.1 - 0.041 13.2 11.1 0.041 13.2 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RR_TM4-6 PF06459.7 ETO05561.1 - 0.13 12.1 11.0 0.13 12.1 7.6 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 POX PF07526.6 ETO05561.1 - 0.52 10.5 5.7 0.54 10.4 3.9 1.1 1 0 0 1 1 1 0 Associated with HOX Conotoxin PF02950.12 ETO05561.1 - 0.71 10.7 2.7 1 10.1 1.9 1.4 1 0 0 1 1 1 0 Conotoxin RNA_polI_A34 PF08208.6 ETO05561.1 - 1 9.0 22.0 1 8.9 15.2 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 SpoVR PF04293.8 ETO05561.1 - 1.2 7.4 6.0 1.3 7.3 4.1 1.0 1 0 0 1 1 1 0 SpoVR like protein PBP_sp32 PF07222.7 ETO05561.1 - 1.7 7.7 13.6 1.9 7.6 9.4 1.0 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF972 PF06156.8 ETO05561.1 - 2.7 8.3 8.8 3 8.2 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) FAM176 PF14851.1 ETO05561.1 - 3.7 7.2 6.2 4.3 7.0 4.3 1.1 1 0 0 1 1 1 0 FAM176 family RP-C_C PF11800.3 ETO05561.1 - 4.2 7.0 7.3 4.3 6.9 5.1 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region DDHD PF02862.12 ETO05561.1 - 6.1 6.5 8.7 6 6.6 6.0 1.1 1 0 0 1 1 1 0 DDHD domain SHR3_chaperone PF08229.6 ETO05561.1 - 6.9 5.5 6.5 6.3 5.7 4.5 1.3 1 0 0 1 1 1 0 ER membrane protein SH3 GAGA_bind PF06217.7 ETO05561.1 - 7.5 6.4 10.9 8 6.3 7.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RNase_H2-Ydr279 PF09468.5 ETO05561.1 - 8.3 5.5 13.3 8.3 5.5 9.2 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Sec62 PF03839.11 ETO05561.1 - 9.1 5.6 12.2 8.9 5.6 8.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 MukE PF04288.8 ETO05562.1 - 0.035 12.9 0.7 0.064 12.0 0.3 1.5 1 1 0 1 1 1 0 MukE-like family Secretogranin_V PF05281.6 ETO05562.1 - 0.2 11.0 2.7 0.26 10.6 1.9 1.3 1 0 0 1 1 1 0 Neuroendocrine protein 7B2 precursor (Secretogranin V) Mycobact_memb PF05423.8 ETO05563.1 - 0.18 11.5 1.2 4 7.1 0.3 2.9 2 1 0 2 2 2 0 Mycobacterium membrane protein Menin PF05053.8 ETO05564.1 - 0.08 11.1 10.1 0.08 11.1 7.0 1.2 1 0 0 1 1 1 0 Menin Nop14 PF04147.7 ETO05564.1 - 0.082 10.8 19.3 0.099 10.5 13.4 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 ETO05564.1 - 0.11 11.7 13.6 0.14 11.4 9.4 1.2 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 ETO05564.1 - 0.14 10.6 16.9 0.17 10.3 11.7 1.1 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 ETO05564.1 - 0.22 10.5 15.7 0.26 10.3 10.9 1.1 1 0 0 1 1 1 0 BUD22 DUF2457 PF10446.4 ETO05564.1 - 0.39 9.3 15.6 0.47 9.1 10.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Raftlin PF15250.1 ETO05564.1 - 1.1 7.7 10.6 1.3 7.5 7.4 1.2 1 0 0 1 1 1 0 Raftlin BTV_NS2 PF04514.7 ETO05564.1 - 1.3 7.8 13.7 1.6 7.5 9.5 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Hid1 PF12722.2 ETO05564.1 - 2.1 5.9 24.5 2.3 5.7 17.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.9 ETO05564.1 - 2.9 5.8 15.8 3.7 5.4 11.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Utp14 PF04615.8 ETO05564.1 - 4 5.4 21.0 4.9 5.1 14.6 1.0 1 0 0 1 1 1 0 Utp14 protein DUF605 PF04652.11 ETO05564.1 - 8.8 5.6 22.5 11 5.3 15.6 1.2 1 0 0 1 1 1 0 Vta1 like YMF19 PF02326.10 ETO05566.1 - 0.011 16.2 2.2 0.011 16.2 1.5 1.6 2 0 0 2 2 2 0 Plant ATP synthase F0 DUF3139 PF11337.3 ETO05567.1 - 1.8 8.8 7.5 14 6.0 1.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3139) DENN PF02141.16 ETO05568.1 - 2.4e-47 161.0 3.0 2.4e-47 161.0 2.0 3.4 5 0 0 5 5 5 1 DENN (AEX-3) domain dDENN PF03455.14 ETO05568.1 - 3.7e-15 55.7 4.0 1.2e-14 54.1 2.8 1.9 1 0 0 1 1 1 1 dDENN domain Collagen PF01391.13 ETO05568.1 - 0.0094 15.4 4.2 0.017 14.6 2.9 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Hexapep PF00132.19 ETO05568.1 - 0.2 11.2 4.1 0.49 10.0 2.9 1.6 1 0 0 1 1 1 0 Bacterial transferase hexapeptide (six repeats) zf-BED PF02892.10 ETO05569.1 - 0.26 11.0 2.8 2.5 7.9 0.2 2.8 2 0 0 2 2 2 0 BED zinc finger DUF4140 PF13600.1 ETO05569.1 - 4.6 7.7 11.0 3.2 8.2 1.3 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) YjcQ PF09639.5 ETO05570.1 - 0.076 13.1 1.0 0.57 10.3 0.1 2.7 2 0 0 2 2 2 0 YjcQ protein Sigma_reg_N PF13800.1 ETO05571.1 - 0.18 11.8 3.1 0.35 10.9 2.2 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal WD40 PF00400.27 ETO05572.1 - 7.9e-11 41.4 2.3 3.6e-06 26.6 0.2 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Corona_S1 PF01600.11 ETO05572.1 - 0.0043 15.4 0.5 0.0049 15.2 0.3 1.0 1 0 0 1 1 1 1 Coronavirus S1 glycoprotein Nup160 PF11715.3 ETO05572.1 - 0.058 11.5 0.0 0.061 11.4 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 NDUF_B6 PF09782.4 ETO05572.1 - 0.064 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit NRN1 PF15056.1 ETO05573.1 - 0.23 11.4 1.5 0.28 11.1 0.5 1.6 1 1 0 1 1 1 0 Neuritin protein family HEAT_2 PF13646.1 ETO05574.1 - 5.8e-07 29.7 0.0 0.011 16.0 0.0 3.4 2 1 2 4 4 4 3 HEAT repeats RHD3 PF05879.7 ETO05574.1 - 0.002 16.1 1.1 0.0028 15.6 0.4 1.4 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) UME PF08064.8 ETO05574.1 - 0.022 14.7 2.9 3.4 7.6 0.1 3.4 2 1 1 3 3 3 0 UME (NUC010) domain NACHT PF05729.7 ETO05575.1 - 6e-17 61.7 0.0 4.8e-16 58.8 0.0 2.4 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 ETO05575.1 - 1.3e-05 25.2 0.0 4.8e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 ETO05575.1 - 0.015 15.5 3.3 0.3 11.3 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 ETO05575.1 - 0.027 14.6 0.3 0.32 11.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 ETO05575.1 - 0.06 13.1 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain DUF2956 PF11169.3 ETO05576.1 - 0.052 13.5 3.1 0.083 12.8 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) CDC45 PF02724.9 ETO05576.1 - 0.081 10.9 5.2 0.092 10.7 3.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Hydrolase_3 PF08282.7 ETO05576.1 - 0.38 10.3 3.2 0.44 10.0 2.2 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF1510 PF07423.6 ETO05576.1 - 0.41 9.9 14.2 0.63 9.3 9.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FAM176 PF14851.1 ETO05576.1 - 0.57 9.8 4.8 0.74 9.4 3.3 1.4 1 0 0 1 1 1 0 FAM176 family DUF1682 PF07946.9 ETO05576.1 - 0.57 8.9 7.9 0.8 8.5 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Daxx PF03344.10 ETO05576.1 - 1.3 7.4 11.0 1.2 7.4 7.6 1.1 1 0 0 1 1 1 0 Daxx Family TRAP_alpha PF03896.11 ETO05576.1 - 2.1 7.2 6.8 2.2 7.1 4.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Peptidase_S49_N PF08496.5 ETO05576.1 - 7.9 6.2 9.7 6.4 6.5 5.9 1.5 1 1 0 1 1 1 0 Peptidase family S49 N-terminal WD40 PF00400.27 ETO05577.1 - 2.1e-55 182.7 11.1 1.4e-15 56.4 0.5 5.0 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 ETO05577.1 - 2.2e-08 34.0 0.1 0.00035 20.3 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO05577.1 - 3.5e-05 23.3 1.1 7.7 6.3 0.0 4.8 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO05577.1 - 6.3e-05 21.3 0.4 0.013 13.6 0.0 3.1 1 1 2 3 3 3 1 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 ETO05577.1 - 0.00041 19.2 0.3 0.22 10.3 0.3 2.4 1 1 1 2 2 2 2 Coatomer WD associated region Cytochrom_D1 PF02239.11 ETO05577.1 - 0.00043 18.6 0.2 0.052 11.8 0.0 2.2 1 1 2 3 3 3 2 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO05577.1 - 0.0012 18.0 0.6 4.1 6.4 0.0 3.6 1 1 2 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Resistin PF06954.6 ETO05577.1 - 0.0013 19.0 0.4 8.7 6.6 0.0 3.7 3 1 2 5 5 5 1 Resistin Nucleoporin_N PF08801.6 ETO05577.1 - 0.0045 15.8 2.0 0.24 10.1 1.4 3.0 1 1 0 1 1 1 1 Nup133 N terminal like Proteasome_A_N PF10584.4 ETO05577.1 - 0.0074 15.5 5.8 3 7.2 0.0 4.1 4 0 0 4 4 4 1 Proteasome subunit A N-terminal signature PQQ_2 PF13360.1 ETO05577.1 - 0.018 14.5 0.2 0.091 12.2 0.1 1.9 1 1 0 1 1 1 0 PQQ-like domain Hira PF07569.6 ETO05577.1 - 0.04 13.1 0.4 3.9 6.6 0.0 3.3 2 1 1 4 4 4 0 TUP1-like enhancer of split DUF4221 PF13970.1 ETO05577.1 - 0.04 13.2 0.0 0.69 9.1 0.0 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4221) WD40 PF00400.27 ETO05578.1 - 1.3e-31 107.2 14.8 4.1e-09 35.9 0.1 6.9 6 1 0 6 6 6 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO05578.1 - 0.00012 20.5 0.3 0.014 13.6 0.1 2.3 1 1 2 3 3 3 3 Cytochrome D1 heme domain PD40 PF07676.7 ETO05578.1 - 0.0026 17.4 0.3 0.83 9.3 0.1 2.9 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat DUF4221 PF13970.1 ETO05578.1 - 0.068 12.4 0.8 0.13 11.5 0.1 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4221) DUF3601 PF12208.3 ETO05578.1 - 0.068 13.1 0.0 0.73 9.8 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3601) Proteasome_A_N PF10584.4 ETO05578.1 - 0.81 9.0 3.6 9.7 5.6 0.0 2.9 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature PPR PF01535.15 ETO05579.1 - 4.4e-13 48.2 5.0 0.001 18.8 0.0 4.4 4 0 0 4 4 4 4 PPR repeat PPR_2 PF13041.1 ETO05579.1 - 2.4e-12 46.5 6.2 9.3e-09 35.1 0.3 3.6 2 1 1 3 3 3 3 PPR repeat family PPR_3 PF13812.1 ETO05579.1 - 1.6e-08 34.1 0.0 0.03 14.5 0.0 4.3 5 0 0 5 5 5 3 Pentatricopeptide repeat domain PPR_1 PF12854.2 ETO05579.1 - 1e-06 28.1 0.4 0.012 15.0 0.0 3.4 3 0 0 3 3 3 2 PPR repeat PP2C PF00481.16 ETO05580.1 - 2.1e-08 33.8 0.2 1.3e-07 31.3 0.1 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C ATP-synt_ab PF00006.20 ETO05580.1 - 0.035 13.6 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain CheY-binding PF09078.6 ETO05580.1 - 0.091 12.7 0.2 0.19 11.7 0.2 1.5 1 0 0 1 1 1 0 CheY binding IpaD PF06511.6 ETO05581.1 - 0.083 11.8 0.1 0.094 11.7 0.1 1.0 1 0 0 1 1 1 0 Invasion plasmid antigen IpaD Gal-bind_lectin PF00337.17 ETO05581.1 - 0.1 11.9 0.3 0.11 11.8 0.2 1.2 1 0 0 1 1 1 0 Galactoside-binding lectin Flu_M1 PF00598.14 ETO05589.1 - 0.088 12.2 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 Influenza Matrix protein (M1) DUF485 PF04341.7 ETO05589.1 - 0.094 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 PB1-F2 PF11986.3 ETO05591.1 - 0.13 12.3 1.5 8.9 6.4 0.0 2.9 2 1 0 2 2 2 0 Influenza A Proapoptotic protein Adeno_E3 PF06040.6 ETO05592.1 - 0.012 15.6 0.8 0.021 14.7 0.6 1.4 1 0 0 1 1 1 0 Adenovirus E3 protein DUF2430 PF10353.4 ETO05592.1 - 0.043 13.9 2.1 0.072 13.2 1.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2430) DUF4367 PF14285.1 ETO05592.1 - 0.14 11.4 0.4 0.2 10.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4367) EVI2A PF05399.6 ETO05592.1 - 0.14 11.3 2.9 0.2 10.8 2.0 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) DM PF00751.13 ETO05592.1 - 0.18 11.3 2.7 0.3 10.6 1.9 1.3 1 0 0 1 1 1 0 DM DNA binding domain FANCI_S3 PF14677.1 ETO05594.1 - 0.018 14.4 2.4 0.027 13.8 1.6 1.2 1 0 0 1 1 1 0 FANCI solenoid 3 RGS-like PF09128.6 ETO05594.1 - 0.047 13.1 0.1 0.066 12.7 0.1 1.4 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain PMSR PF01625.16 ETO05595.1 - 0.042 13.7 0.1 0.089 12.6 0.1 1.5 1 0 0 1 1 1 0 Peptide methionine sulfoxide reductase DUF4446 PF14584.1 ETO05596.1 - 0.0083 15.9 2.2 0.01 15.6 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4446) Med28 PF11594.3 ETO05596.1 - 0.036 14.3 1.2 0.041 14.1 0.8 1.3 1 0 0 1 1 1 0 Mediator complex subunit 28 Bac_GDH PF05088.7 ETO05596.1 - 0.037 11.4 0.4 0.039 11.3 0.3 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase SpoIISA_toxin PF14171.1 ETO05596.1 - 0.12 11.6 1.0 0.13 11.4 0.7 1.1 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system DUF948 PF06103.6 ETO05596.1 - 1.4 8.8 6.8 2.2 8.1 4.7 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DivIC PF04977.10 ETO05597.1 - 0.12 11.8 13.1 0.28 10.6 9.1 1.6 1 0 0 1 1 1 0 Septum formation initiator Pex16 PF08610.5 ETO05597.1 - 1.6 7.6 13.5 0.34 9.8 4.5 2.4 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) Med15 PF09606.5 ETO05597.1 - 2.1 6.4 29.1 3.1 5.8 20.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CHD5 PF04420.9 ETO05597.1 - 3.2 7.4 11.1 8.5 6.0 7.7 1.7 1 0 0 1 1 1 0 CHD5-like protein TMCO5 PF14992.1 ETO05598.1 - 0.014 14.5 0.6 0.023 13.8 0.4 1.3 1 0 0 1 1 1 0 TMCO5 family FAM177 PF14774.1 ETO05598.1 - 0.47 10.3 3.0 1.5 8.7 0.3 2.1 2 0 0 2 2 2 0 FAM177 family Dehydrin PF00257.14 ETO05599.1 - 0.02 15.2 9.7 0.026 14.8 6.7 1.1 1 0 0 1 1 1 0 Dehydrin Spore_coat_CotO PF14153.1 ETO05599.1 - 0.32 10.4 14.4 0.36 10.2 10.0 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Nop14 PF04147.7 ETO05599.1 - 0.77 7.5 27.2 0.76 7.6 18.9 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 ETO05599.1 - 1 8.5 25.5 1.2 8.3 17.6 1.3 1 0 0 1 1 1 0 SDA1 Tim54 PF11711.3 ETO05599.1 - 1.3 7.5 10.2 1.3 7.5 7.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SAPS PF04499.10 ETO05599.1 - 1.3 7.5 12.2 1.3 7.6 8.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TFIIF_alpha PF05793.7 ETO05599.1 - 1.5 7.0 31.0 1.9 6.7 21.5 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Atrophin-1 PF03154.10 ETO05599.1 - 1.8 6.5 12.3 2.5 6.1 8.5 1.2 1 0 0 1 1 1 0 Atrophin-1 family DUF1510 PF07423.6 ETO05599.1 - 2.6 7.3 25.1 3.7 6.8 17.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 ETO05599.1 - 3.3 5.6 18.3 3.3 5.6 12.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 ETO05599.1 - 3.5 5.9 26.9 3.8 5.8 18.7 1.2 1 0 0 1 1 1 0 Daxx Family HSP70 PF00012.15 ETO05599.1 - 4.2 5.1 10.4 4.6 5.0 7.2 1.0 1 0 0 1 1 1 0 Hsp70 protein Raftlin PF15250.1 ETO05599.1 - 5.3 5.4 10.8 6.1 5.2 7.5 1.1 1 0 0 1 1 1 0 Raftlin Merozoite_SPAM PF07133.6 ETO05599.1 - 5.4 6.8 31.4 7.4 6.4 21.8 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CKAP2_C PF15297.1 ETO05599.1 - 5.8 5.6 13.0 7.1 5.3 9.0 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Ycf1 PF05758.7 ETO05599.1 - 7.2 4.1 12.4 7.1 4.2 8.6 1.0 1 0 0 1 1 1 0 Ycf1 YqfQ PF14181.1 ETO05599.1 - 8.4 6.4 16.3 9.4 6.2 10.6 1.7 2 0 0 2 2 2 0 YqfQ-like protein DUF4617 PF15395.1 ETO05600.1 - 0.00091 17.4 0.5 0.00091 17.4 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4617) Arm_2 PF04826.8 ETO05601.1 - 0.015 14.4 0.2 0.33 10.0 0.1 2.1 1 1 1 2 2 2 0 Armadillo-like Arm PF00514.18 ETO05601.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat Di19_C PF14571.1 ETO05604.1 - 0.25 11.6 3.7 0.13 12.5 1.3 1.5 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal IFNGR1 PF07140.6 ETO05604.1 - 8.7 6.0 10.5 14 5.3 7.2 1.6 1 1 0 1 1 1 0 Interferon gamma receptor (IFNGR1) DUF4365 PF14280.1 ETO05605.1 - 0.023 14.3 2.3 0.049 13.3 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4365) OATP PF03137.15 ETO05605.1 - 0.035 12.1 4.9 0.044 11.8 3.4 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DNA_pol3_delta2 PF13177.1 ETO05605.1 - 0.3 10.7 12.1 0.39 10.3 8.4 1.1 1 0 0 1 1 1 0 DNA polymerase III, delta subunit PEX11 PF05648.9 ETO05605.1 - 0.45 9.7 10.2 5.3 6.2 7.0 2.0 1 1 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) YfhO PF09586.5 ETO05605.1 - 2.7 5.9 10.3 3 5.7 7.2 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO RNA_pol_Rpb1_5 PF04998.12 ETO05605.1 - 3.6 6.7 7.1 4 6.6 4.9 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 AAA_11 PF13086.1 ETO05605.1 - 4.3 6.8 12.3 5.2 6.5 8.5 1.1 1 0 0 1 1 1 0 AAA domain Nefa_Nip30_N PF10187.4 ETO05605.1 - 8.2 6.6 19.4 4.2 7.6 11.2 1.8 1 1 1 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 Ank_3 PF13606.1 ETO05606.1 - 0.038 14.2 0.2 0.63 10.4 0.0 2.7 2 1 1 3 3 3 0 Ankyrin repeat DUF2286 PF10051.4 ETO05607.1 - 0.0092 15.6 0.1 0.029 14.0 0.1 1.8 1 1 1 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2286) C_GCAxxG_C_C PF09719.5 ETO05608.1 - 0.0098 15.6 0.2 0.2 11.4 0.0 2.4 2 1 0 3 3 3 1 Putative redox-active protein (C_GCAxxG_C_C) HEAT_2 PF13646.1 ETO05608.1 - 0.043 14.0 0.0 4.6 7.5 0.0 2.2 2 0 0 2 2 2 0 HEAT repeats DUF2757 PF10955.3 ETO05608.1 - 0.082 13.1 0.2 0.25 11.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2757) DUF2225 PF09986.4 ETO05608.1 - 0.082 12.3 1.4 0.084 12.3 0.3 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) E1-E2_ATPase PF00122.15 ETO05609.1 - 3.7e-53 179.9 0.1 6.2e-53 179.1 0.1 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 ETO05609.1 - 6e-34 118.3 0.0 1.7e-33 116.8 0.0 1.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 ETO05609.1 - 2.1e-25 89.2 0.0 5.2e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus HAD PF12710.2 ETO05609.1 - 2.4e-17 63.7 0.3 1.3e-16 61.3 0.1 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETO05609.1 - 4.1e-13 49.1 0.0 7.8e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 ETO05609.1 - 1.2e-09 38.1 3.0 3.1e-06 26.9 1.0 2.7 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 ETO05609.1 - 0.00023 21.0 0.0 0.0035 17.1 0.0 2.6 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 ETO05609.1 - 0.01 16.0 0.0 0.035 14.3 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Exostosin PF03016.10 ETO05609.1 - 0.063 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Exostosin family Drf_GBD PF06371.8 ETO05611.1 - 0.025 13.9 0.1 0.031 13.6 0.1 1.2 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain Ank_3 PF13606.1 ETO05612.1 - 0.02 15.0 0.0 0.1 12.9 0.0 2.3 1 0 0 1 1 1 0 Ankyrin repeat Ank_4 PF13637.1 ETO05612.1 - 0.057 13.9 0.1 0.14 12.6 0.1 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) CCDC144C PF14915.1 ETO05615.1 - 0.0001 21.3 4.6 0.0001 21.3 3.2 3.0 3 1 0 3 3 3 2 CCDC144C protein coiled-coil region TMEM154 PF15102.1 ETO05615.1 - 0.0015 18.2 0.5 0.0015 18.2 0.3 2.9 3 0 0 3 3 3 1 TMEM154 protein family IncA PF04156.9 ETO05615.1 - 0.0021 17.7 0.2 0.0021 17.7 0.1 2.9 3 0 0 3 3 2 2 IncA protein DUF912 PF06024.7 ETO05615.1 - 0.0054 16.7 0.6 0.0054 16.7 0.4 3.7 4 0 0 4 4 4 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Shisa PF13908.1 ETO05615.1 - 0.0071 16.5 4.7 0.0071 16.5 3.3 3.6 3 1 0 3 3 3 1 Wnt and FGF inhibitory regulator ASFV_J13L PF05568.6 ETO05615.1 - 0.021 14.3 0.8 0.052 13.0 0.5 1.6 1 0 0 1 1 1 0 African swine fever virus J13L protein YqbF PF14553.1 ETO05615.1 - 0.045 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 YqbF, hypothetical protein domain DUF4064 PF13273.1 ETO05615.1 - 0.062 13.4 0.5 0.062 13.4 0.3 3.6 5 0 0 5 5 4 0 Protein of unknown function (DUF4064) VIT1 PF01988.14 ETO05615.1 - 0.084 12.3 0.1 2 7.8 0.0 2.7 3 0 0 3 3 3 0 VIT family DUF4164 PF13747.1 ETO05615.1 - 0.13 12.4 8.0 0.089 12.9 1.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) T2SF PF00482.18 ETO05615.1 - 0.61 10.0 2.3 1.6 8.6 0.3 2.6 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Secretin_N_2 PF07655.8 ETO05615.1 - 0.78 10.1 17.3 0.12 12.7 8.3 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain EphA2_TM PF14575.1 ETO05615.1 - 3.3 8.1 12.5 0.14 12.5 1.2 3.4 3 0 0 3 3 2 0 Ephrin type-A receptor 2 transmembrane domain SET PF00856.23 ETO05616.1 - 2.8e-07 30.9 0.6 5.1e-07 30.1 0.4 1.4 1 0 0 1 1 1 1 SET domain Phi-29_GP16_7 PF06720.6 ETO05616.1 - 0.059 13.0 0.3 0.22 11.1 0.2 1.8 1 1 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 ubiquitin PF00240.18 ETO05617.1 - 5.4e-31 105.7 0.9 9.5e-31 105.0 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 ETO05617.1 - 2.1e-17 62.5 0.4 3.8e-17 61.7 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 ETO05617.1 - 4.3e-05 23.6 0.1 0.00016 21.8 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.4 ETO05617.1 - 0.048 13.8 0.1 0.12 12.6 0.0 1.6 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 ETO05617.1 - 0.095 12.5 1.8 0.12 12.2 0.0 2.0 2 1 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like DUF3439 PF11921.3 ETO05619.1 - 1.9 8.2 6.7 3 7.6 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Pkinase PF00069.20 ETO05620.1 - 9.8e-06 24.8 0.0 1.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO05620.1 - 0.093 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase TipAS PF07739.8 ETO05621.1 - 0.044 14.1 0.2 0.079 13.2 0.1 1.4 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain Snapin_Pallidin PF14712.1 ETO05621.1 - 0.17 12.1 1.3 2.6 8.4 0.3 2.3 2 0 0 2 2 2 0 Snapin/Pallidin TRM PF02005.11 ETO05622.1 - 0.0029 16.6 0.5 0.0047 15.9 0.3 1.3 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase CbiK PF06180.6 ETO05622.1 - 0.019 14.0 1.0 0.028 13.5 0.1 1.7 2 1 0 2 2 2 0 Cobalt chelatase (CbiK) Amidoligase_2 PF12224.3 ETO05622.1 - 0.078 12.5 0.9 2.7 7.5 0.1 2.1 2 0 0 2 2 2 0 Putative amidoligase enzyme Laps PF10169.4 ETO05622.1 - 4 7.6 12.2 0.19 11.9 1.8 2.3 2 0 0 2 2 2 0 Learning-associated protein WD40 PF00400.27 ETO05623.1 - 1e-13 50.5 2.1 3.7e-12 45.6 0.1 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO05623.1 - 0.043 11.9 0.0 0.11 10.5 0.0 1.6 2 0 0 2 2 2 0 Nucleoporin Nup120/160 HTH_16 PF12645.2 ETO05623.1 - 0.051 13.5 0.3 0.13 12.1 0.2 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain RE_MjaI PF09568.5 ETO05624.1 - 0.074 12.5 2.3 0.081 12.4 1.6 1.1 1 0 0 1 1 1 0 MjaI restriction endonuclease Phage_min_tail PF05939.8 ETO05624.1 - 0.087 12.7 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Phage minor tail protein zf-RanBP PF00641.13 ETO05625.1 - 1.8e-05 23.7 1.7 4.7e-05 22.4 1.2 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-UBR PF02207.15 ETO05625.1 - 0.0019 17.8 0.5 0.0044 16.7 0.3 1.6 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Peptidase_C34 PF05413.6 ETO05625.1 - 0.1 12.6 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Putative closterovirus papain-like endopeptidase Pkinase PF00069.20 ETO05626.1 - 1.5e-12 47.2 0.5 1.5e-12 47.2 0.3 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO05626.1 - 3.5e-07 29.5 0.4 3.5e-07 29.5 0.3 2.3 1 1 1 2 2 2 1 Protein tyrosine kinase Mvb12 PF09452.5 ETO05626.1 - 0.21 11.7 4.5 0.65 10.2 0.4 2.5 1 1 1 2 2 2 0 ESCRT-I subunit Mvb12 TMEM51 PF15345.1 ETO05626.1 - 9.3 5.8 9.1 14 5.2 6.3 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Pkinase PF00069.20 ETO05627.1 - 6.1e-38 130.4 0.0 7.5e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO05627.1 - 5.4e-23 81.3 0.0 7.2e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO05627.1 - 4e-07 29.3 0.0 5.1e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETO05627.1 - 0.067 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PT-HINT PF07591.6 ETO05628.1 - 0.079 12.8 0.1 0.082 12.7 0.0 1.2 1 0 0 1 1 1 0 Pretoxin HINT domain Mago_nashi PF02792.9 ETO05629.1 - 7.2e-68 226.7 1.4 9e-68 226.4 1.0 1.0 1 0 0 1 1 1 1 Mago nashi protein DUF3506 PF12014.3 ETO05629.1 - 0.057 13.2 0.3 0.14 11.9 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3506) Fucose_iso_C PF02952.12 ETO05630.1 - 0.0081 15.6 0.0 0.012 15.0 0.0 1.3 1 1 0 1 1 1 1 L-fucose isomerase, C-terminal domain PTS_2-RNA PF01885.11 ETO05630.1 - 0.009 15.3 1.1 0.011 15.0 0.8 1.3 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Myosin_tail_1 PF01576.14 ETO05630.1 - 0.013 13.3 15.9 0.015 13.0 11.0 1.1 1 0 0 1 1 1 0 Myosin tail Phage_GP20 PF06810.6 ETO05630.1 - 0.47 9.8 17.7 0.21 11.0 6.7 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF3449 PF11931.3 ETO05631.1 - 3.6e-05 23.3 6.3 5.2e-05 22.8 4.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) zf-C2H2_2 PF12756.2 ETO05631.1 - 0.0048 16.9 0.4 0.011 15.7 0.1 1.7 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) DUF1644 PF07800.7 ETO05631.1 - 0.0049 16.7 1.2 0.0086 15.9 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1644) PRP21_like_P PF12230.3 ETO05631.1 - 0.01 15.3 4.9 0.11 11.9 0.7 2.1 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein DAP_B PF07930.7 ETO05633.1 - 0.14 11.8 0.0 20 5.0 0.0 3.2 2 1 2 4 4 4 0 D-aminopeptidase, domain B PA PF02225.17 ETO05634.1 - 0.00023 20.7 0.0 0.00038 20.0 0.0 1.3 1 0 0 1 1 1 1 PA domain adh_short PF00106.20 ETO05635.1 - 4.2e-24 85.3 0.0 7.9e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETO05635.1 - 1.1e-12 47.9 0.0 1.8e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETO05635.1 - 2.5e-07 30.7 0.0 3.4e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 ETO05635.1 - 0.0031 17.5 0.0 0.017 15.1 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 ETO05635.1 - 0.025 13.7 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ApbA PF02558.11 ETO05635.1 - 0.042 13.3 0.0 0.08 12.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 ETO05635.1 - 0.083 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase U-box PF04564.10 ETO05636.1 - 2.6e-21 75.3 0.0 7.8e-21 73.8 0.0 1.8 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.3 ETO05636.1 - 1.8e-06 27.3 0.0 4.9e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 ETO05636.1 - 0.00071 19.2 0.6 0.0027 17.3 0.0 2.3 3 0 0 3 3 3 1 RING-type zinc-finger Gly-zipper_OmpA PF13436.1 ETO05636.1 - 0.0024 17.5 6.7 0.0044 16.6 4.6 1.3 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Rtf2 PF04641.7 ETO05636.1 - 0.032 13.4 0.1 0.087 12.0 0.0 1.7 2 0 0 2 2 2 0 Rtf2 RING-finger TCTP PF00838.12 ETO05636.1 - 0.034 14.1 0.1 0.078 12.9 0.1 1.5 1 0 0 1 1 1 0 Translationally controlled tumour protein RNA_pol_N PF01194.12 ETO05636.1 - 0.083 12.9 0.0 0.35 10.9 0.0 2.1 2 0 0 2 2 2 0 RNA polymerases N / 8 kDa subunit DUF148 PF02520.12 ETO05636.1 - 0.083 12.6 1.2 0.83 9.4 0.4 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF148 POR_N PF01855.14 ETO05636.1 - 0.11 12.0 0.9 0.19 11.2 0.6 1.4 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Gly-zipper_Omp PF13488.1 ETO05636.1 - 0.36 10.5 21.4 1.5 8.5 14.8 1.9 1 1 0 1 1 1 0 Glycine zipper MSP1_C PF07462.6 ETO05636.1 - 0.39 9.0 4.6 0.18 10.1 1.4 1.6 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus Rick_17kDa_Anti PF05433.10 ETO05636.1 - 1.6 8.4 20.7 3.1 7.5 14.4 1.5 1 0 0 1 1 1 0 Glycine zipper 2TM domain DUF3262 PF11660.3 ETO05637.1 - 0.027 14.5 0.2 0.042 13.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) Tad PF13400.1 ETO05637.1 - 0.1 12.6 0.4 0.14 12.1 0.3 1.2 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like DUF3236 PF11576.3 ETO05638.1 - 0.036 13.4 0.1 0.036 13.4 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3236) NACHT PF05729.7 ETO05639.1 - 0.23 11.0 2.7 0.96 9.0 0.0 2.6 3 0 0 3 3 3 0 NACHT domain RasGEF PF00617.14 ETO05641.1 - 0.0027 17.4 0.1 0.0067 16.1 0.0 1.7 2 0 0 2 2 2 1 RasGEF domain SPOB_ab PF14682.1 ETO05641.1 - 0.038 13.7 1.8 0.046 13.5 1.2 1.2 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal Transposase_1 PF01359.13 ETO05642.1 - 0.0096 15.6 0.4 0.0096 15.6 0.3 3.3 3 1 1 4 4 4 1 Transposase (partial DDE domain) DUF2508 PF10704.4 ETO05642.1 - 0.071 13.2 4.1 0.26 11.5 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) DUF489 PF04356.7 ETO05642.1 - 1.7 8.1 7.3 1.3 8.5 3.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF489) zf-BED PF02892.10 ETO05643.1 - 0.13 12.0 0.2 0.13 12.0 0.1 2.2 2 0 0 2 2 2 0 BED zinc finger RAI16-like PF10257.4 ETO05644.1 - 0.075 11.9 0.1 0.092 11.6 0.1 1.0 1 0 0 1 1 1 0 Retinoic acid induced 16-like protein FTO_CTD PF12934.2 ETO05645.1 - 0.038 13.5 0.5 0.11 12.0 0.0 1.8 1 1 1 2 2 2 0 FTO C-terminal domain WD40 PF00400.27 ETO05646.1 - 8e-28 95.2 16.4 1.8e-10 40.2 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO05646.1 - 2.5e-11 42.4 0.8 9.1e-05 20.7 0.0 3.0 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO05646.1 - 0.0081 14.9 1.3 3.9 6.1 0.0 2.8 1 1 2 3 3 3 2 Nup133 N terminal like DUF1900 PF08954.6 ETO05646.1 - 0.014 14.8 0.0 5.7 6.4 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1900) DUF4221 PF13970.1 ETO05646.1 - 0.068 12.4 1.3 0.57 9.4 0.7 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4221) Kelch_2 PF07646.10 ETO05646.1 - 0.57 10.0 4.6 0.86 9.4 0.1 3.0 3 1 0 3 3 3 0 Kelch motif SpvD PF05563.7 ETO05647.1 - 0.074 12.5 0.9 0.096 12.1 0.2 1.5 2 0 0 2 2 2 0 Salmonella plasmid virulence protein SpvD Neur_chan_memb PF02932.11 ETO05648.1 - 0.014 15.3 1.5 0.019 14.8 1.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AUX_IAA PF02309.11 ETO05648.1 - 0.6 9.8 8.5 0.76 9.4 5.9 1.1 1 0 0 1 1 1 0 AUX/IAA family Raftlin PF15250.1 ETO05648.1 - 4.5 5.6 8.1 5.4 5.4 5.6 1.1 1 0 0 1 1 1 0 Raftlin DUF1764 PF08576.5 ETO05649.1 - 0.015 16.0 8.1 0.022 15.5 5.6 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) PAF-AH_p_II PF03403.8 ETO05649.1 - 0.045 12.0 6.3 0.053 11.8 4.3 1.0 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DUF4175 PF13779.1 ETO05649.1 - 0.049 11.3 32.8 0.056 11.1 22.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TFIIA PF03153.8 ETO05649.1 - 0.085 12.7 18.7 0.088 12.6 13.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 ETO05649.1 - 0.09 11.0 31.0 0.1 10.8 21.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 ETO05649.1 - 0.14 11.4 15.7 0.15 11.4 10.8 1.1 1 0 0 1 1 1 0 Vta1 like DUF3360 PF11840.3 ETO05649.1 - 0.2 9.9 1.3 0.24 9.6 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3360) HD-ZIP_N PF04618.7 ETO05649.1 - 0.24 11.9 7.8 0.34 11.4 5.4 1.3 1 1 0 1 1 1 0 HD-ZIP protein N terminus Pal1 PF08316.6 ETO05649.1 - 0.28 11.6 4.4 0.38 11.2 3.0 1.3 1 0 0 1 1 1 0 Pal1 cell morphology protein FimP PF09766.4 ETO05649.1 - 0.29 10.1 20.3 0.38 9.7 14.1 1.2 1 0 0 1 1 1 0 Fms-interacting protein Vma12 PF11712.3 ETO05649.1 - 0.32 10.7 8.1 0.39 10.4 5.6 1.2 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3464 PF11947.3 ETO05649.1 - 0.35 10.3 5.0 0.47 9.9 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Exonuc_VII_L PF02601.10 ETO05649.1 - 0.38 9.9 8.7 0.41 9.7 6.0 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit AIF_C PF14721.1 ETO05649.1 - 0.41 10.9 7.4 0.54 10.5 5.1 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF2043 PF09740.4 ETO05649.1 - 0.61 10.2 5.8 0.77 9.8 4.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2043) Neur_chan_memb PF02932.11 ETO05649.1 - 0.71 9.7 4.2 0.8 9.5 2.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region eIF-3_zeta PF05091.7 ETO05649.1 - 0.93 8.0 16.2 1.1 7.8 11.2 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SID-1_RNA_chan PF13965.1 ETO05649.1 - 1.3 7.1 7.6 1.5 6.9 5.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Med15 PF09606.5 ETO05649.1 - 1.7 6.7 52.9 2 6.4 36.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ctr PF04145.10 ETO05649.1 - 1.8 8.5 4.7 2.2 8.3 3.3 1.2 1 0 0 1 1 1 0 Ctr copper transporter family SprA-related PF12118.3 ETO05649.1 - 1.9 7.7 29.8 2.4 7.3 20.7 1.1 1 0 0 1 1 1 0 SprA-related family PPP4R2 PF09184.6 ETO05649.1 - 2.4 7.6 11.1 3.2 7.2 7.7 1.2 1 0 0 1 1 1 0 PPP4R2 RED_N PF07808.8 ETO05649.1 - 3.3 6.8 18.2 4.2 6.5 12.6 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region EIF4E-T PF10477.4 ETO05649.1 - 3.6 6.2 15.1 4.8 5.8 10.5 1.2 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E BORG_CEP PF14957.1 ETO05649.1 - 4.2 8.3 8.1 2.7 8.9 4.6 1.4 2 0 0 2 2 1 0 Cdc42 effector DUF853 PF05872.7 ETO05649.1 - 4.9 5.3 10.7 5.9 5.1 7.4 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Folate_carrier PF01770.13 ETO05649.1 - 6.7 5.0 8.4 7.7 4.9 5.8 1.0 1 0 0 1 1 1 0 Reduced folate carrier UPF0560 PF10577.4 ETO05649.1 - 7.2 4.7 18.5 8.1 4.5 12.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DDRGK PF09756.4 ETO05649.1 - 8.1 5.7 20.3 10 5.4 14.1 1.1 1 0 0 1 1 1 0 DDRGK domain DUF1448 PF07289.6 ETO05649.1 - 8.4 5.2 12.9 10 4.8 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1448) Hid1 PF12722.2 ETO05649.1 - 9.4 3.7 13.2 11 3.5 9.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Spc7 PF08317.6 ETO05651.1 - 0.00052 18.7 7.5 0.00052 18.7 5.2 5.1 5 0 0 5 5 5 3 Spc7 kinetochore protein IncA PF04156.9 ETO05651.1 - 0.0015 18.1 0.6 0.0015 18.1 0.5 4.9 5 1 0 5 5 4 1 IncA protein WEMBL PF05701.6 ETO05651.1 - 0.0015 17.0 65.0 0.047 12.1 15.5 4.2 3 1 0 4 4 4 3 Weak chloroplast movement under blue light MscS_porin PF12795.2 ETO05651.1 - 0.0018 17.6 4.4 0.0018 17.6 3.0 4.6 5 1 0 5 5 5 2 Mechanosensitive ion channel porin domain TPR_MLP1_2 PF07926.7 ETO05651.1 - 0.0028 17.3 12.2 0.0028 17.3 8.5 6.5 6 2 0 6 6 6 3 TPR/MLP1/MLP2-like protein Cast PF10174.4 ETO05651.1 - 0.058 11.4 53.9 0.068 11.2 10.4 3.6 3 1 0 3 3 3 0 RIM-binding protein of the cytomatrix active zone CENP-F_leu_zip PF10473.4 ETO05651.1 - 0.08 12.8 58.5 0.12 12.1 5.3 5.5 4 1 0 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1043 PF06295.7 ETO05651.1 - 0.12 12.0 29.0 0.17 11.5 2.1 6.2 3 2 0 3 3 3 0 Protein of unknown function (DUF1043) Flagellin_C PF00700.16 ETO05651.1 - 2.6 8.2 16.2 0.28 11.3 2.2 3.9 3 0 0 3 3 3 0 Bacterial flagellin C-terminal helical region Fez1 PF06818.10 ETO05651.1 - 3.9 7.4 42.4 0.085 12.8 7.4 4.1 4 1 0 4 4 4 0 Fez1 Tropomyosin PF00261.15 ETO05651.1 - 4.1 6.4 51.3 0.065 12.3 7.0 3.8 3 0 0 3 3 3 0 Tropomyosin YMF19 PF02326.10 ETO05652.1 - 1.4 9.5 5.6 0.68 10.5 2.1 1.8 2 0 0 2 2 2 0 Plant ATP synthase F0 14-3-3 PF00244.15 ETO05653.1 - 7.1e-87 290.3 3.6 8.6e-87 290.1 2.5 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 ETO05653.1 - 2.2e-06 27.5 0.6 4.9e-06 26.3 0.4 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO05653.1 - 0.0024 17.4 0.3 0.0075 15.8 0.2 1.9 1 1 0 1 1 1 1 TPR repeat TPR_8 PF13181.1 ETO05653.1 - 0.057 13.2 9.0 0.16 11.8 2.8 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 ETO05653.1 - 0.1 12.5 0.1 1.3 9.1 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETO05653.1 - 1.1 9.0 4.2 1.1 9.0 0.3 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETO05653.1 - 2.6 8.2 8.8 2.8 8.0 1.7 3.2 3 2 0 3 3 3 0 Tetratricopeptide repeat NACHT PF05729.7 ETO05654.1 - 2.9e-07 30.2 0.0 7.8e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETO05654.1 - 0.00039 20.5 0.0 0.0014 18.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 ETO05654.1 - 0.001 18.7 0.1 0.36 10.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 ETO05654.1 - 0.0044 17.3 0.0 0.0044 17.3 0.0 4.3 5 1 0 5 5 5 1 AAA domain AAA PF00004.24 ETO05654.1 - 0.013 15.6 0.0 0.047 13.8 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 ETO05654.1 - 0.029 13.9 0.2 0.17 11.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 ETO05654.1 - 0.048 14.4 3.0 0.095 13.5 0.0 3.0 4 0 0 4 4 4 0 AAA domain EST1_DNA_bind PF10373.4 ETO05654.1 - 0.054 12.7 6.8 0.013 14.6 0.8 2.6 2 1 0 2 2 2 0 Est1 DNA/RNA binding domain Snf7 PF03357.16 ETO05655.1 - 1.5e-14 53.7 22.3 2.1e-14 53.3 15.4 1.3 1 1 0 1 1 1 1 Snf7 Ist1 PF03398.9 ETO05655.1 - 0.00037 19.9 6.4 0.0021 17.4 4.4 1.9 1 1 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Metal_resist PF13801.1 ETO05655.1 - 0.0098 15.8 0.9 0.0098 15.8 0.6 2.4 1 1 0 2 2 2 1 Heavy-metal resistance PG_binding_4 PF12229.3 ETO05655.1 - 0.022 14.9 7.9 0.93 9.7 0.7 2.7 2 2 0 2 2 2 0 Putative peptidoglycan binding domain DUF3166 PF11365.3 ETO05655.1 - 0.034 14.6 2.0 0.034 14.6 1.4 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF3166) SurA_N PF09312.6 ETO05655.1 - 0.072 12.9 3.7 0.51 10.2 1.4 2.5 1 1 1 2 2 2 0 SurA N-terminal domain DUF1160 PF06648.6 ETO05655.1 - 0.13 12.0 3.2 0.27 11.0 2.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1160) MULE PF10551.4 ETO05655.1 - 0.22 11.7 1.0 0.74 10.0 0.7 2.0 1 1 0 1 1 1 0 MULE transposase domain HTH_15 PF12324.3 ETO05655.1 - 0.62 9.7 3.7 7.6 6.2 0.2 2.9 1 1 1 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase Matrilin_ccoil PF10393.4 ETO05655.1 - 0.8 9.1 6.2 1.6 8.1 0.1 3.3 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF3793 PF12672.2 ETO05655.1 - 2.2 7.8 6.6 0.45 10.0 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3793) DUF1664 PF07889.7 ETO05655.1 - 2.3 8.0 10.7 0.25 11.1 3.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF972 PF06156.8 ETO05655.1 - 2.6 8.4 20.0 1.1 9.6 0.8 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF2935 PF11155.3 ETO05655.1 - 3.3 7.8 15.1 9.6 6.3 2.6 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) PilJ PF13675.1 ETO05655.1 - 5.9 7.2 9.5 0.36 11.1 1.8 2.2 2 1 1 3 3 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term WD40 PF00400.27 ETO05657.1 - 0.0003 20.5 0.0 3.2 7.7 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat Glyco_hydro_18 PF00704.23 ETO05658.1 - 3.3e-15 56.3 0.4 4.1e-15 56.0 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Nanovirus_C8 PF05629.6 ETO05658.1 - 0.11 12.2 0.3 0.65 9.7 0.0 2.1 1 1 1 2 2 2 0 Nanovirus component 8 (C8) protein Daxx PF03344.10 ETO05659.1 - 0.002 16.7 24.0 0.0027 16.2 16.6 1.1 1 0 0 1 1 1 1 Daxx Family CENP-T PF15511.1 ETO05659.1 - 0.056 12.6 9.6 0.083 12.1 6.6 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF2762 PF10960.3 ETO05659.1 - 0.11 12.2 0.1 0.29 10.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) zf-TRAF PF02176.13 ETO05659.1 - 0.29 11.5 15.2 0.12 12.7 2.7 3.5 2 1 1 3 3 3 0 TRAF-type zinc finger Menin PF05053.8 ETO05659.1 - 4.5 5.3 11.5 5.9 4.9 7.9 1.1 1 0 0 1 1 1 0 Menin zf-TRAF PF02176.13 ETO05660.1 - 7.7e-12 45.4 7.8 1.3e-11 44.6 5.4 1.4 1 0 0 1 1 1 1 TRAF-type zinc finger SNARE PF05739.14 ETO05660.1 - 0.057 13.1 0.6 0.09 12.4 0.4 1.4 1 0 0 1 1 1 0 SNARE domain DUF4116 PF13475.1 ETO05660.1 - 0.059 12.8 0.1 12 5.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Sina PF03145.11 ETO05660.1 - 2.2 7.8 8.5 2.3 7.8 5.4 1.5 1 1 0 1 1 1 0 Seven in absentia protein family DivIC PF04977.10 ETO05661.1 - 0.0024 17.3 1.3 0.0048 16.3 0.9 1.5 1 0 0 1 1 1 1 Septum formation initiator DUF2140 PF09911.4 ETO05661.1 - 0.0063 15.7 1.6 0.013 14.6 1.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2140) DUF4094 PF13334.1 ETO05661.1 - 0.012 16.0 0.7 0.024 15.0 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) FHIPEP PF00771.15 ETO05661.1 - 0.021 13.1 0.2 0.031 12.6 0.1 1.2 1 0 0 1 1 1 0 FHIPEP family DUF1456 PF07308.8 ETO05661.1 - 0.031 14.3 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) FAM176 PF14851.1 ETO05661.1 - 0.032 13.9 0.2 0.064 12.9 0.2 1.5 1 0 0 1 1 1 0 FAM176 family Bap31 PF05529.7 ETO05661.1 - 0.057 12.8 3.0 0.1 12.0 2.1 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Phage_Gp23 PF10669.4 ETO05661.1 - 0.058 13.5 3.6 0.12 12.5 2.5 1.5 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) RasGAP PF00616.14 ETO05661.1 - 0.064 12.9 1.5 6.2 6.4 0.6 2.3 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase DUF3789 PF12664.2 ETO05661.1 - 0.071 12.4 0.2 0.18 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) DUF506 PF04720.7 ETO05661.1 - 0.085 12.4 1.8 0.12 11.9 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF506) OAD_gamma PF04277.8 ETO05661.1 - 0.098 13.0 0.5 0.19 12.1 0.4 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Tetraspannin PF00335.15 ETO05661.1 - 0.12 11.6 0.1 0.12 11.6 0.1 2.8 3 0 0 3 3 2 0 Tetraspanin family Nucleoside_tran PF01733.13 ETO05661.1 - 1.8 7.6 14.1 0.045 12.9 2.8 2.3 2 1 0 2 2 2 0 Nucleoside transporter WD40 PF00400.27 ETO05662.1 - 6.2e-56 184.4 24.5 2.3e-10 39.9 0.1 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO05662.1 - 3e-06 25.6 5.7 0.21 9.7 0.0 4.8 1 1 4 5 5 5 5 Nucleoporin Nup120/160 DUF1914 PF08932.5 ETO05662.1 - 0.64 10.0 8.8 1.9 8.5 1.0 4.2 3 2 0 3 3 3 0 Domain of unknown function (DUF1914) ELM2 PF01448.19 ETO05663.1 - 0.0011 19.6 0.0 0.0024 18.4 0.0 1.6 1 0 0 1 1 1 1 ELM2 domain SPRY PF00622.23 ETO05664.1 - 3.1e-11 43.4 0.2 7.7e-11 42.1 0.1 1.7 1 0 0 1 1 1 1 SPRY domain zf-RanBP PF00641.13 ETO05664.1 - 1.1e-06 27.5 4.1 2e-06 26.7 2.8 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF2956 PF11169.3 ETO05664.1 - 0.094 12.6 0.2 0.094 12.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Atrophin-1 PF03154.10 ETO05664.1 - 0.39 8.8 5.8 0.068 11.3 1.3 1.5 2 0 0 2 2 2 0 Atrophin-1 family UPF0242 PF06785.6 ETO05666.1 - 0.39 9.3 8.2 0.56 8.8 5.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) RbsD_FucU PF05025.8 ETO05666.1 - 1.1 9.5 3.9 1.1 9.6 1.5 1.8 1 1 1 2 2 2 0 RbsD / FucU transport protein family CorA PF01544.13 ETO05666.1 - 1.2 8.1 8.3 0.63 9.0 4.5 1.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein TFIIA PF03153.8 ETO05666.1 - 1.8 8.3 23.3 2.4 7.9 16.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RAP1 PF07218.6 ETO05666.1 - 8.7 4.3 8.5 12 3.8 5.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Gemin6 PF06372.7 ETO05668.1 - 8.2e-10 38.2 0.1 5.6e-08 32.2 0.1 2.4 1 1 0 1 1 1 1 Gemin6 protein AD PF09793.4 ETO05668.1 - 0.071 12.9 1.4 0.13 12.1 0.4 1.9 1 1 1 2 2 2 0 Anticodon-binding domain TMV_coat PF00721.16 ETO05668.1 - 0.096 12.6 1.2 0.52 10.2 0.0 2.0 2 0 0 2 2 2 0 Virus coat protein (TMV like) RNB PF00773.14 ETO05670.1 - 0.023 13.9 2.9 0.029 13.6 2.0 1.2 1 0 0 1 1 1 0 RNB domain zf-C3HC4_4 PF15227.1 ETO05670.1 - 0.067 13.0 1.2 0.067 13.0 0.8 2.7 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING DUF723 PF05265.8 ETO05670.1 - 0.26 11.0 0.2 0.26 11.0 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF723) zf-C3HC4_2 PF13923.1 ETO05670.1 - 5.9 6.9 11.1 14 5.8 1.9 3.8 4 1 1 5 5 5 0 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.27 ETO05671.1 - 1.2e-52 174.0 21.2 3.9e-11 42.3 0.0 6.7 6 1 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO05671.1 - 9.6e-12 43.8 3.4 0.023 12.8 0.1 5.0 2 1 3 5 5 5 5 Nucleoporin Nup120/160 Methyltransf_25 PF13649.1 ETO05671.1 - 0.031 14.6 0.0 9.9 6.5 0.0 3.9 4 1 0 4 4 4 0 Methyltransferase domain WD40 PF00400.27 ETO05675.1 - 9.6e-20 69.6 0.5 4.8e-10 38.9 0.0 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Kelch_4 PF13418.1 ETO05677.1 - 7.7e-07 28.7 4.1 1.9e-05 24.3 0.0 3.5 3 1 1 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO05677.1 - 3.1e-05 23.9 2.7 0.0033 17.5 0.1 3.8 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 ETO05677.1 - 5.6e-05 22.6 0.2 5.6e-05 22.6 0.1 3.2 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 ETO05677.1 - 0.0033 17.3 1.3 0.0033 17.3 0.9 2.0 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO05677.1 - 0.051 13.7 0.2 0.3 11.2 0.0 2.4 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO05677.1 - 0.067 12.9 0.2 0.067 12.9 0.1 2.7 4 0 0 4 4 4 0 Kelch motif HpcH_HpaI PF03328.9 ETO05678.1 - 1.5e-17 63.2 0.0 4.6e-17 61.6 0.0 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Dynein_IC2 PF11540.3 ETO05678.1 - 0.067 12.5 0.2 0.067 12.5 0.2 1.8 2 0 0 2 2 2 0 Cytoplasmic dynein 1 intermediate chain 2 WD40 PF00400.27 ETO05679.1 - 7.7e-25 85.8 2.5 1.9e-08 33.8 0.0 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO05679.1 - 0.0022 16.7 1.2 0.023 13.4 0.2 2.1 1 1 1 2 2 2 1 Nup133 N terminal like Nup160 PF11715.3 ETO05679.1 - 0.0056 14.8 0.1 0.24 9.5 0.0 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DDE_3 PF13358.1 ETO05680.1 - 4.9e-05 23.1 0.2 5.2e-05 23.0 0.2 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease WD40 PF00400.27 ETO05681.1 - 4e-05 23.3 0.6 0.0065 16.3 0.0 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat WD40 PF00400.27 ETO05682.1 - 1.2e-60 199.3 17.8 3.6e-12 45.6 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO05682.1 - 6e-10 39.1 0.1 0.0021 17.7 0.0 3.0 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO05682.1 - 1.5e-07 29.9 6.6 0.0033 15.6 0.3 4.8 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO05682.1 - 1.7e-06 26.6 0.3 0.15 10.3 0.0 3.6 1 1 3 5 5 5 4 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO05682.1 - 8.5e-05 21.7 1.0 0.13 11.3 0.0 3.6 2 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 ETO05682.1 - 0.00011 21.7 4.1 1.4 8.6 0.0 4.6 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO05682.1 - 0.00033 19.5 10.5 0.28 9.8 0.4 4.8 1 1 4 6 6 6 4 Nup133 N terminal like DPPIV_N PF00930.16 ETO05682.1 - 0.076 11.5 0.4 29 3.0 0.1 3.6 1 1 3 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Kelch_4 PF13418.1 ETO05683.1 - 0.00041 20.0 0.0 0.17 11.6 0.0 2.5 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO05683.1 - 0.00075 19.5 0.1 0.034 14.3 0.0 2.6 2 1 1 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO05683.1 - 0.0073 16.0 0.0 0.13 12.0 0.0 2.5 2 0 0 2 2 2 1 Kelch motif Monellin PF09200.5 ETO05683.1 - 0.013 15.1 0.1 0.034 13.7 0.1 1.8 1 0 0 1 1 1 0 Monellin Kelch_1 PF01344.20 ETO05683.1 - 0.039 13.5 0.3 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 Kelch motif Mlp PF03304.8 ETO05684.1 - 0.0072 16.3 4.6 0.0082 16.1 3.2 1.1 1 0 0 1 1 1 1 Mlp lipoprotein family Prp19_bind PF06991.6 ETO05684.1 - 0.028 13.7 0.6 0.029 13.6 0.4 1.1 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain Med19 PF10278.4 ETO05684.1 - 0.28 10.8 3.6 0.32 10.6 2.5 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 ETRAMP PF09716.5 ETO05684.1 - 4.7 7.2 6.6 9.4 6.2 4.5 1.6 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Myotub-related PF06602.9 ETO05685.1 - 5.7e-93 311.4 9.3 7.8e-62 209.0 3.3 2.3 2 0 0 2 2 2 2 Myotubularin-like phosphatase domain FYVE PF01363.16 ETO05685.1 - 1.6e-13 50.3 10.9 4.8e-13 48.7 7.6 1.8 1 0 0 1 1 1 1 FYVE zinc finger Y_phosphatase3 PF13350.1 ETO05685.1 - 0.18 12.0 0.7 0.77 9.9 0.0 2.2 2 0 0 2 2 2 0 Tyrosine phosphatase family Atrophin-1 PF03154.10 ETO05685.1 - 4.9 5.1 7.8 8.8 4.3 5.4 1.3 1 0 0 1 1 1 0 Atrophin-1 family MoaF PF10703.4 ETO05688.1 - 0.031 13.3 0.0 0.48 9.4 0.0 2.0 2 0 0 2 2 2 0 Molybdenum cofactor biosynthesis protein F Mgr1 PF08602.5 ETO05690.1 - 0.37 9.7 5.0 0.48 9.3 3.5 1.2 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit Glyco_transf_92 PF01697.22 ETO05690.1 - 1.5 8.0 9.3 1.7 7.8 6.4 1.0 1 0 0 1 1 1 0 Glycosyltransferase family 92 Pkinase PF00069.20 ETO05691.1 - 9.6e-39 133.0 0.0 1.4e-38 132.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO05691.1 - 2.7e-12 46.3 0.1 1e-11 44.4 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO05691.1 - 1.3e-06 27.6 0.1 3.1e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETO05691.1 - 0.00028 20.0 0.2 0.003 16.6 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO05691.1 - 0.0038 16.9 0.0 0.0075 16.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 ETO05691.1 - 0.026 13.8 0.0 0.042 13.1 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL EcKinase PF02958.15 ETO05691.1 - 0.086 11.9 0.0 0.23 10.5 0.0 1.6 2 0 0 2 2 2 0 Ecdysteroid kinase HSP70 PF00012.15 ETO05692.1 - 7.5e-05 20.8 0.0 0.0045 14.9 0.0 2.2 1 1 1 2 2 2 2 Hsp70 protein Daxx PF03344.10 ETO05693.1 - 0.13 10.7 19.6 0.14 10.5 13.6 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 ETO05693.1 - 0.2 9.5 19.1 0.22 9.4 13.2 1.1 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.13 ETO05693.1 - 0.78 8.8 9.8 1.3 8.1 6.8 1.4 1 0 0 1 1 1 0 Myc amino-terminal region EBV-NA3 PF05009.7 ETO05693.1 - 2.6 7.2 9.0 4.6 6.4 6.2 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) CENP-B_dimeris PF09026.5 ETO05693.1 - 3.4 7.9 17.1 0.56 10.4 8.8 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DDHD PF02862.12 ETO05693.1 - 4.8 6.9 9.3 8.3 6.1 6.5 1.5 1 0 0 1 1 1 0 DDHD domain DUF3408 PF11888.3 ETO05693.1 - 5.1 7.0 16.7 2.8 7.8 7.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3408) RXT2_N PF08595.6 ETO05693.1 - 6.6 6.5 15.9 45 3.8 9.9 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal CDC45 PF02724.9 ETO05693.1 - 8 4.3 14.4 10 4.0 10.0 1.3 1 0 0 1 1 1 0 CDC45-like protein ALG3 PF05208.8 ETO05694.1 - 3.2e-114 382.0 29.0 3.2e-114 382.0 20.1 2.0 2 1 1 3 3 3 1 ALG3 protein UPF0728 PF15092.1 ETO05694.1 - 0.074 12.9 0.3 0.19 11.6 0.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0728 DUF4661 PF15576.1 ETO05694.1 - 0.55 9.8 3.0 1.1 8.8 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Mitofilin PF09731.4 ETO05696.1 - 8.8 4.8 36.4 0.04 12.5 3.6 3.2 3 0 0 3 3 3 0 Mitochondrial inner membrane protein TMEM138 PF14935.1 ETO05698.1 - 0.019 15.3 0.3 0.033 14.5 0.2 1.4 1 0 0 1 1 1 0 Transmembrane protein 138 DUF4573 PF15140.1 ETO05699.1 - 0.035 13.7 0.1 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4573) Leptin PF02024.10 ETO05699.1 - 3.2 7.3 10.3 2.6 7.6 1.3 2.2 1 1 1 2 2 2 0 Leptin TROVE PF05731.6 ETO05700.1 - 0.11 11.1 8.8 0.13 10.9 6.1 1.1 1 0 0 1 1 1 0 TROVE domain Pex26 PF07163.7 ETO05701.1 - 0.14 11.0 0.0 0.14 11.0 0.0 1.5 2 0 0 2 2 2 0 Pex26 protein Pkinase_Tyr PF07714.12 ETO05703.1 - 1.3e-42 145.6 0.0 1.5e-42 145.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 ETO05703.1 - 4.7e-38 130.8 0.0 5.8e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 ETO05703.1 - 2.7e-05 23.2 0.0 3.4e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETO05703.1 - 0.00014 21.6 0.1 0.00022 21.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 ETO05703.1 - 0.0012 17.9 0.1 0.0016 17.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 ETO05703.1 - 0.044 13.1 0.1 0.23 10.8 0.1 2.0 1 1 1 2 2 2 0 RIO1 family Pkinase_Tyr PF07714.12 ETO05704.1 - 7e-07 28.5 0.3 0.025 13.6 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 ETO05704.1 - 2.2e-06 27.0 0.1 1.5e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain HALZ PF02183.13 ETO05705.1 - 0.00073 19.1 0.3 0.0024 17.5 0.0 2.0 2 0 0 2 2 2 1 Homeobox associated leucine zipper Med4 PF10018.4 ETO05705.1 - 0.0031 16.9 2.2 0.0031 16.9 1.5 2.1 1 1 1 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 Phage_GP20 PF06810.6 ETO05705.1 - 0.0086 15.5 9.1 0.44 9.9 0.2 2.2 2 0 0 2 2 2 2 Phage minor structural protein GP20 Lectin_N PF03954.9 ETO05705.1 - 0.015 14.6 1.6 0.015 14.6 1.1 1.9 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain TMF_DNA_bd PF12329.3 ETO05705.1 - 0.017 14.8 13.2 0.19 11.5 0.0 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.4 ETO05705.1 - 0.024 14.4 7.6 0.04 13.7 2.0 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4618 PF15397.1 ETO05705.1 - 0.028 13.7 11.0 0.018 14.4 3.1 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4618) BLOC1_2 PF10046.4 ETO05705.1 - 0.03 14.4 8.5 0.16 12.1 2.1 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.6 ETO05705.1 - 0.037 12.6 9.8 0.073 11.7 1.9 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF972 PF06156.8 ETO05705.1 - 0.039 14.2 0.8 0.039 14.2 0.6 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF972) HrpB7 PF09486.5 ETO05705.1 - 0.057 13.3 0.1 10 6.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Rootletin PF15035.1 ETO05705.1 - 0.091 12.7 9.0 0.23 11.4 6.2 1.6 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF3584 PF12128.3 ETO05705.1 - 0.096 9.9 6.3 0.12 9.6 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Myosin_HC-like PF07058.6 ETO05705.1 - 0.1 11.6 3.9 0.13 11.3 0.6 2.0 1 1 1 2 2 2 0 Myosin II heavy chain-like GAS PF13851.1 ETO05705.1 - 0.19 10.9 12.6 0.11 11.6 5.2 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.2 ETO05705.1 - 0.21 11.4 13.0 0.12 12.1 4.1 2.2 2 0 0 2 2 2 0 Tropomyosin like DUF948 PF06103.6 ETO05705.1 - 0.22 11.4 4.0 1.5 8.6 0.1 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ADIP PF11559.3 ETO05705.1 - 0.26 11.1 12.7 0.36 10.7 2.1 2.6 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding bZIP_2 PF07716.10 ETO05705.1 - 0.29 10.9 7.0 0.21 11.4 1.9 2.7 2 1 1 3 3 3 0 Basic region leucine zipper bZIP_1 PF00170.16 ETO05705.1 - 0.36 10.8 8.4 10 6.1 0.5 3.4 2 1 1 3 3 3 0 bZIP transcription factor IncA PF04156.9 ETO05705.1 - 0.4 10.2 11.3 0.5 9.9 4.6 2.0 1 1 1 2 2 2 0 IncA protein DUF4201 PF13870.1 ETO05705.1 - 0.48 9.8 12.3 0.75 9.2 3.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) TMF_TATA_bd PF12325.3 ETO05705.1 - 0.48 10.1 10.6 2.2 8.0 0.2 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding ARD PF03079.9 ETO05705.1 - 0.54 10.1 4.2 0.43 10.5 1.8 1.6 1 1 0 1 1 1 0 ARD/ARD' family DUF904 PF06005.7 ETO05705.1 - 0.91 9.8 14.9 2.8 8.3 5.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Mod_r PF07200.8 ETO05705.1 - 0.94 9.3 8.9 0.17 11.8 1.6 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF4164 PF13747.1 ETO05705.1 - 1.3 9.2 5.0 1.1 9.4 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DUF2681 PF10883.3 ETO05705.1 - 2.1 8.6 7.4 1.4 9.1 0.3 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2681) DUF641 PF04859.7 ETO05705.1 - 2.6 7.8 7.3 1.7 8.3 0.6 2.6 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Cep57_CLD_2 PF14197.1 ETO05705.1 - 2.6 8.0 6.3 1.6 8.7 2.4 2.0 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 ATG16 PF08614.6 ETO05705.1 - 4.3 7.1 12.7 20 4.9 5.7 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.6 ETO05705.1 - 5.7 6.9 11.7 3.9 7.4 0.3 3.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Kinesin-relat_1 PF12711.2 ETO05705.1 - 6.7 7.1 7.9 2.4 8.6 0.4 2.9 2 1 0 2 2 2 0 Kinesin motor DivIC PF04977.10 ETO05705.1 - 7.3 6.1 13.7 1.5 8.3 0.9 3.3 2 1 2 4 4 4 0 Septum formation initiator Exostosin PF03016.10 ETO05706.1 - 2.6e-07 29.9 0.4 2e-06 27.0 0.2 2.0 1 1 0 1 1 1 1 Exostosin family DUF2490 PF10677.4 ETO05706.1 - 0.0038 16.5 0.6 0.0063 15.8 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2490) Zip PF02535.17 ETO05707.1 - 3.2e-10 39.5 9.8 2.9e-09 36.3 4.9 2.2 1 1 1 2 2 2 2 ZIP Zinc transporter 2OG-FeII_Oxy_5 PF13759.1 ETO05707.1 - 0.0091 16.2 1.6 0.014 15.6 0.7 1.6 1 1 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase NIF PF03031.13 ETO05709.1 - 4.7e-19 68.6 0.0 7.3e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF1497 PF07384.6 ETO05709.1 - 0.14 12.3 0.7 0.29 11.3 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1497) MS_channel PF00924.13 ETO05711.1 - 6.3e-07 28.9 5.6 1.8e-06 27.4 3.9 1.7 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF2063 PF09836.4 ETO05712.1 - 0.019 14.9 0.4 2.1 8.3 0.0 3.8 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2063) DNA_pol3_gamma3 PF12169.3 ETO05712.1 - 0.13 12.0 0.4 0.38 10.5 0.3 1.8 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III FUR PF01475.14 ETO05713.1 - 0.8 9.6 5.7 0.32 10.9 2.2 1.7 1 1 0 1 1 1 0 Ferric uptake regulator family WD40 PF00400.27 ETO05714.1 - 2e-11 43.3 10.7 3.6e-05 23.4 2.9 3.9 3 1 1 4 4 4 3 WD domain, G-beta repeat RNA_pol_Rpb4 PF03874.11 ETO05715.1 - 3.9e-11 42.9 0.4 7.7e-11 42.0 0.1 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb4 WD40 PF00400.27 ETO05716.1 - 7.7e-72 234.8 6.2 1.3e-11 43.8 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO05716.1 - 1.8e-12 46.1 0.7 0.0016 16.7 0.0 4.5 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO05716.1 - 5e-08 31.6 1.2 0.024 12.9 0.0 3.4 1 1 3 4 4 4 4 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO05716.1 - 5e-07 29.4 0.1 3.1e-05 23.5 0.0 2.7 1 1 2 3 3 3 3 PQQ-like domain PD40 PF07676.7 ETO05716.1 - 1.7e-05 24.3 5.1 0.93 9.2 0.0 5.8 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 ETO05716.1 - 0.0021 17.1 2.0 1.3 8.0 0.0 3.9 2 2 3 5 5 5 1 Protein of unknown function (DUF1258) Resistin PF06954.6 ETO05716.1 - 0.0024 18.0 0.0 55 4.1 0.0 4.5 2 2 3 5 5 5 0 Resistin Hira PF07569.6 ETO05716.1 - 0.018 14.2 0.2 2.2 7.4 0.0 3.6 2 1 3 5 5 5 0 TUP1-like enhancer of split Pkinase PF00069.20 ETO05718.1 - 6.2e-05 22.2 0.0 7.1e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain ABC2_membrane_3 PF12698.2 ETO05718.1 - 0.00014 21.0 0.1 0.00017 20.7 0.1 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein RDD PF06271.7 ETO05718.1 - 0.0071 16.2 1.4 0.01 15.7 0.9 1.3 1 0 0 1 1 1 1 RDD family Oxidored_q3 PF00499.15 ETO05718.1 - 0.09 12.5 6.2 0.15 11.8 4.3 1.3 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Methyltransf_21 PF05050.7 ETO05719.1 - 3.4e-08 33.6 0.3 7.3e-08 32.5 0.2 1.6 1 1 0 1 1 1 1 Methyltransferase FkbM domain DUF1493 PF07377.7 ETO05719.1 - 0.12 12.4 0.3 0.65 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1493) DUF1510 PF07423.6 ETO05720.1 - 7.1e-05 22.2 5.9 0.0001 21.7 4.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Amnionless PF14828.1 ETO05720.1 - 0.00043 18.8 1.1 0.00056 18.5 0.8 1.2 1 0 0 1 1 1 1 Amnionless Zip PF02535.17 ETO05720.1 - 0.0031 16.5 0.5 0.0041 16.1 0.3 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Hid1 PF12722.2 ETO05720.1 - 0.006 14.3 10.4 0.0061 14.3 7.2 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Mem_trans PF03547.13 ETO05720.1 - 0.02 13.2 2.4 0.022 13.0 1.7 1.2 1 0 0 1 1 1 0 Membrane transport protein ABC2_membrane_3 PF12698.2 ETO05720.1 - 0.027 13.4 1.4 0.035 13.1 0.9 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Neur_chan_memb PF02932.11 ETO05720.1 - 0.03 14.2 4.1 0.037 13.9 2.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PA26 PF04636.8 ETO05720.1 - 0.056 12.1 1.2 0.059 12.0 0.8 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SID-1_RNA_chan PF13965.1 ETO05720.1 - 0.088 10.9 1.6 0.11 10.6 1.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Utp14 PF04615.8 ETO05720.1 - 0.16 10.1 13.3 0.16 10.0 9.2 1.1 1 0 0 1 1 1 0 Utp14 protein Raftlin PF15250.1 ETO05720.1 - 0.19 10.2 7.2 0.24 9.8 5.0 1.1 1 0 0 1 1 1 0 Raftlin HCO3_cotransp PF00955.16 ETO05720.1 - 0.32 9.6 2.7 0.42 9.2 1.9 1.1 1 0 0 1 1 1 0 HCO3- transporter family Cellulose_synt PF03552.9 ETO05720.1 - 0.6 8.3 2.4 0.68 8.1 1.7 1.1 1 0 0 1 1 1 0 Cellulose synthase Folate_carrier PF01770.13 ETO05720.1 - 1.2 7.5 5.3 2.6 6.4 3.7 1.6 1 1 0 1 1 1 0 Reduced folate carrier Spore_YhcN_YlaJ PF09580.5 ETO05720.1 - 2.7 8.0 21.0 4.4 7.3 14.6 1.4 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF3807 PF12720.2 ETO05720.1 - 3 7.9 13.2 4.7 7.3 9.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) OATP PF03137.15 ETO05720.1 - 3.4 5.6 5.1 10 4.0 3.5 1.7 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family RP-C_C PF11800.3 ETO05720.1 - 3.4 7.3 8.9 5.3 6.6 6.2 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region Tim54 PF11711.3 ETO05720.1 - 5.1 5.5 8.3 6.2 5.3 5.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4175 PF13779.1 ETO05720.1 - 6.9 4.2 11.5 8.8 3.8 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RabGAP-TBC PF00566.13 ETO05721.1 - 1.5e-15 57.2 5.8 1.7e-13 50.5 3.9 2.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain zf-B_box PF00643.19 ETO05721.1 - 2.1e-05 24.2 7.6 3.7e-05 23.5 5.3 1.4 1 0 0 1 1 1 1 B-box zinc finger HCaRG PF07258.9 ETO05721.1 - 0.037 13.5 0.2 0.08 12.4 0.2 1.5 1 0 0 1 1 1 0 HCaRG protein DUF4291 PF14124.1 ETO05722.1 - 4.4e-48 163.3 0.4 5.6e-48 162.9 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) DUF4050 PF13259.1 ETO05722.1 - 0.0034 17.2 0.4 0.0052 16.7 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) WD40 PF00400.27 ETO05723.1 - 1.8e-36 122.7 30.7 1.2e-09 37.7 0.1 6.9 6 1 1 7 7 7 5 WD domain, G-beta repeat Pentapeptide PF00805.17 ETO05723.1 - 3.1e-07 29.4 0.7 8.7e-07 28.0 0.5 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO05723.1 - 4.1e-06 26.4 0.4 1.7e-05 24.5 0.1 2.0 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 ETO05723.1 - 0.0011 18.7 3.5 0.0023 17.7 0.8 2.8 2 1 0 2 2 2 1 Pentapeptide repeats (9 copies) Nup160 PF11715.3 ETO05723.1 - 0.01 13.9 3.8 0.41 8.7 0.0 3.7 2 1 1 4 4 4 0 Nucleoporin Nup120/160 Mid2 PF04478.7 ETO05723.1 - 0.027 13.8 0.2 0.55 9.6 0.0 2.4 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor CBM_6 PF03422.10 ETO05723.1 - 0.18 11.9 1.2 0.65 10.1 0.0 2.5 3 0 0 3 3 3 0 Carbohydrate binding module (family 6) DUF2286 PF10051.4 ETO05724.1 - 0.066 12.8 0.3 0.78 9.3 0.0 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2286) ELH PF02323.10 ETO05725.1 - 0.1 11.7 1.0 0.12 11.5 0.7 1.3 1 0 0 1 1 1 0 Egg-laying hormone precursor CaM_binding PF07839.6 ETO05725.1 - 0.85 9.8 4.2 0.29 11.3 0.8 1.7 2 0 0 2 2 2 0 Plant calmodulin-binding domain WD40 PF00400.27 ETO05726.1 - 3.9e-21 74.0 3.3 5.1e-06 26.1 0.0 3.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO05726.1 - 0.00075 17.7 0.1 0.29 9.2 0.0 2.2 1 1 0 2 2 2 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO05726.1 - 0.0025 17.5 0.2 0.26 11.0 0.0 2.3 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 ETO05726.1 - 0.045 12.4 1.9 6.1 5.4 0.4 2.6 1 1 1 2 2 2 0 Nup133 N terminal like UPF0565 PF10561.4 ETO05727.1 - 2.9e-10 39.5 2.5 3.9e-06 25.9 0.2 3.0 1 1 2 3 3 3 3 Uncharacterised protein family UPF0565 Phage_Orf51 PF06194.6 ETO05727.1 - 0.023 14.7 0.1 0.044 13.8 0.1 1.5 1 0 0 1 1 1 0 Phage Conserved Open Reading Frame 51 DUF3801 PF12687.2 ETO05728.1 - 0.00088 18.9 2.6 0.0011 18.5 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3801) E7 PF00527.13 ETO05728.1 - 0.05 13.7 1.5 0.064 13.4 0.4 1.6 1 1 1 2 2 2 0 E7 protein, Early protein DUF4131 PF13567.1 ETO05728.1 - 0.072 12.5 0.1 0.098 12.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) TRAP_alpha PF03896.11 ETO05728.1 - 0.097 11.6 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FdhD-NarQ PF02634.10 ETO05728.1 - 0.12 11.8 0.2 0.15 11.4 0.1 1.1 1 0 0 1 1 1 0 FdhD/NarQ family ACI44 PF15270.1 ETO05728.1 - 1.1 9.2 7.1 2.3 8.2 1.9 2.3 2 0 0 2 2 2 0 Metallo-carboxypeptidase inhibitor zf-CCHC_3 PF13917.1 ETO05729.1 - 0.00016 21.2 0.4 0.00049 19.7 0.3 1.8 1 0 0 1 1 1 1 Zinc knuckle PHF5 PF03660.9 ETO05729.1 - 0.0034 17.4 0.2 0.005 16.8 0.2 1.4 1 0 0 1 1 1 1 PHF5-like protein zf-CCHC PF00098.18 ETO05729.1 - 0.0035 17.2 1.2 0.0054 16.5 0.8 1.3 1 0 0 1 1 1 1 Zinc knuckle DUF257 PF03192.8 ETO05729.1 - 0.027 13.7 0.9 0.027 13.7 0.6 1.5 2 0 0 2 2 2 0 Pyrococcus protein of unknown function, DUF257 Chisel PF15355.1 ETO05730.1 - 0.00017 21.5 0.1 0.00017 21.5 0.0 2.6 2 1 1 3 3 3 1 Stretch-responsive small skeletal muscle X protein, Chisel Tim54 PF11711.3 ETO05730.1 - 0.48 8.9 6.1 0.71 8.3 4.2 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2413 PF10310.4 ETO05730.1 - 2 7.1 16.3 2.2 7.0 11.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) AAA_14 PF13173.1 ETO05731.1 - 1.1e-05 25.3 0.0 5.1e-05 23.1 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 ETO05731.1 - 1.2e-05 25.0 0.0 4.1e-05 23.3 0.0 1.9 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.24 ETO05731.1 - 4.8e-05 23.5 0.0 0.00011 22.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 ETO05731.1 - 0.00022 21.5 0.0 0.0007 19.9 0.0 1.9 1 0 0 1 1 1 1 ABC transporter RNA_helicase PF00910.17 ETO05731.1 - 0.0024 18.0 0.0 0.052 13.7 0.0 3.0 3 0 0 3 3 3 1 RNA helicase AAA_17 PF13207.1 ETO05731.1 - 0.0025 18.5 0.1 0.016 15.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 ETO05731.1 - 0.0031 16.4 0.1 0.0063 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 ETO05731.1 - 0.0041 17.2 0.0 0.021 14.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETO05731.1 - 0.007 16.6 2.0 0.023 15.0 0.1 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 ETO05731.1 - 0.01 15.4 0.2 0.12 11.9 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 ETO05731.1 - 0.021 14.5 2.8 0.059 13.0 0.0 2.8 2 1 1 3 3 3 0 Archaeal ATPase AAA_2 PF07724.9 ETO05731.1 - 0.026 14.4 0.8 0.11 12.4 0.0 2.4 4 0 0 4 4 4 0 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 ETO05731.1 - 0.03 14.3 0.0 0.073 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain MCM PF00493.18 ETO05731.1 - 0.031 13.0 2.2 0.048 12.4 0.0 2.3 4 0 0 4 4 4 0 MCM2/3/5 family Sigma54_activat PF00158.21 ETO05731.1 - 0.066 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.1 ETO05732.1 - 0.019 15.1 0.0 0.12 12.5 0.0 2.5 1 1 0 1 1 1 0 AAA domain DUF938 PF06080.7 ETO05733.1 - 0.0073 15.8 0.1 0.0097 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) CAAP1 PF15335.1 ETO05737.1 - 0.06 13.5 0.6 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 Caspase activity and apoptosis inhibitor 1 Glyco_transf_8 PF01501.15 ETO05738.1 - 1.4e-08 34.3 6.8 1.6e-08 34.1 3.3 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 8 Methyltransf_16 PF10294.4 ETO05738.1 - 0.011 15.1 0.4 0.032 13.7 0.3 1.7 1 0 0 1 1 1 0 Putative methyltransferase Adeno_52K PF03052.10 ETO05738.1 - 0.079 12.1 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Adenoviral protein L1 52/55-kDa LRR_6 PF13516.1 ETO05739.1 - 6.3e-06 25.7 26.1 0.21 11.7 0.1 7.4 7 0 0 7 7 7 4 Leucine Rich repeat LRR_1 PF00560.28 ETO05739.1 - 1.6e-05 24.2 12.6 1 9.6 0.1 7.0 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_4 PF12799.2 ETO05739.1 - 0.00018 21.0 17.3 0.062 12.9 1.2 4.5 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) PTE PF02126.13 ETO05739.1 - 0.13 11.2 0.2 0.25 10.3 0.1 1.4 1 0 0 1 1 1 0 Phosphotriesterase family LRR_8 PF13855.1 ETO05739.1 - 0.14 11.9 22.6 0.21 11.3 4.8 4.8 3 1 0 3 3 3 0 Leucine rich repeat LRR_7 PF13504.1 ETO05739.1 - 4 8.0 16.1 21 5.9 0.1 5.8 6 0 0 6 6 6 0 Leucine rich repeat YgaB PF14182.1 ETO05740.1 - 0.0092 16.1 0.5 0.014 15.5 0.3 1.2 1 0 0 1 1 1 1 YgaB-like protein End3 PF12761.2 ETO05740.1 - 0.07 12.7 0.4 0.1 12.2 0.3 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Pilt PF15453.1 ETO05741.1 - 6 6.4 10.6 6.7 6.2 7.4 1.0 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions WD40 PF00400.27 ETO05742.1 - 3.1e-60 198.0 12.7 1.6e-11 43.5 0.0 7.1 8 0 0 8 8 8 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO05742.1 - 3.3e-07 29.4 6.9 0.082 11.6 0.2 4.9 1 1 4 5 5 5 4 Nup133 N terminal like PQQ_2 PF13360.1 ETO05742.1 - 8.2e-07 28.7 0.0 2.2e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO05742.1 - 1.7e-05 23.3 1.0 0.035 12.4 0.1 3.2 1 1 2 3 3 3 3 Cytochrome D1 heme domain Nup160 PF11715.3 ETO05742.1 - 5.2e-05 21.5 1.0 0.76 7.8 0.0 3.7 2 2 1 3 3 3 3 Nucleoporin Nup120/160 Nbas_N PF15492.1 ETO05742.1 - 0.0002 20.5 0.6 0.39 9.7 0.0 4.4 2 1 3 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Vif PF00559.12 ETO05742.1 - 0.026 14.4 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral Vif (Viral infectivity) protein Proteasome_A_N PF10584.4 ETO05742.1 - 0.13 11.6 4.4 24 4.3 0.3 3.7 3 1 0 3 3 3 0 Proteasome subunit A N-terminal signature UPF0118 PF01594.11 ETO05742.1 - 0.28 10.1 4.9 0.072 12.0 1.1 1.6 2 0 0 2 2 2 0 Domain of unknown function DUF20 PD40 PF07676.7 ETO05742.1 - 0.33 10.6 4.5 11 5.7 0.0 4.8 5 1 0 5 5 5 0 WD40-like Beta Propeller Repeat Ribosomal_S3Ae PF01015.13 ETO05743.1 - 3.7e-10 39.4 2.3 5e-10 39.0 1.6 1.2 1 0 0 1 1 1 1 Ribosomal S3Ae family SRI PF08236.6 ETO05743.1 - 0.078 12.9 0.3 0.12 12.3 0.2 1.3 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain Macoilin PF09726.4 ETO05744.1 - 0.026 12.8 9.1 0.027 12.7 6.3 1.0 1 0 0 1 1 1 0 Transmembrane protein MIP-T3 PF10243.4 ETO05744.1 - 0.38 9.1 25.7 0.45 8.9 17.8 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DHHW PF14286.1 ETO05744.1 - 0.46 9.7 7.7 0.54 9.5 5.3 1.0 1 0 0 1 1 1 0 DHHW protein DUF2201_N PF13203.1 ETO05744.1 - 0.5 9.4 6.6 0.6 9.2 4.6 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain Sec62 PF03839.11 ETO05744.1 - 1.2 8.4 20.3 1.9 7.8 14.1 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 FAM60A PF15396.1 ETO05744.1 - 1.6 8.4 12.5 1.9 8.1 8.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.12 ETO05744.1 - 2.4 6.8 5.4 2.7 6.7 3.8 1.0 1 0 0 1 1 1 0 Presenilin DUF2151 PF10221.4 ETO05744.1 - 2.9 5.9 11.1 3.2 5.8 7.7 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator YqfQ PF14181.1 ETO05744.1 - 3.5 7.6 16.5 4.8 7.2 11.4 1.3 1 0 0 1 1 1 0 YqfQ-like protein DUF1510 PF07423.6 ETO05744.1 - 4.1 6.7 20.8 5 6.4 14.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NPR3 PF03666.8 ETO05744.1 - 4.4 5.7 16.5 5.1 5.5 11.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Vfa1 PF08432.5 ETO05744.1 - 5.8 6.8 21.8 7.3 6.5 15.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 GAGA_bind PF06217.7 ETO05744.1 - 8.5 6.2 16.1 9.5 6.0 11.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Paramyxo_ncap PF00973.14 ETO05744.1 - 8.8 4.8 9.5 9.4 4.7 6.6 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Vfa1 PF08432.5 ETO05745.1 - 0.01 15.8 8.5 0.011 15.7 5.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NST1 PF13945.1 ETO05745.1 - 0.21 11.6 8.3 0.27 11.3 5.8 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Tubulin PF00091.20 ETO05746.1 - 1.3e-58 198.3 0.0 1.9e-58 197.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO05746.1 - 8.8e-27 93.6 0.1 2.4e-26 92.2 0.0 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 ETO05746.1 - 0.048 13.1 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain DSPn PF14671.1 ETO05747.1 - 0.53 10.2 6.3 0.76 9.7 4.1 1.5 1 1 1 2 2 2 0 Dual specificity protein phosphatase, N-terminal half Flu_NS2 PF00601.14 ETO05747.1 - 1.9 8.7 5.4 0.26 11.5 1.0 1.6 2 0 0 2 2 2 0 Influenza non-structural protein (NS2) Peptidase_M20 PF01546.23 ETO05748.1 - 1.2e-12 47.7 0.0 2.4e-07 30.4 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M20/M25/M40 M20_dimer PF07687.9 ETO05748.1 - 3.2e-05 23.6 0.0 7.4e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain SAM_1 PF00536.25 ETO05749.1 - 2.2e-07 30.9 0.1 3.3e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO05749.1 - 0.0013 18.5 0.2 0.0026 17.5 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Sec62 PF03839.11 ETO05749.1 - 0.019 14.3 0.5 0.028 13.8 0.4 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 WD40 PF00400.27 ETO05750.1 - 2.8e-25 87.1 22.0 1.2e-06 28.2 0.0 7.9 7 1 0 7 7 7 5 WD domain, G-beta repeat DASH_Dam1 PF08653.5 ETO05753.1 - 0.15 11.8 1.1 15 5.4 0.2 2.7 2 0 0 2 2 2 0 DASH complex subunit Dam1 Lzipper-MIP1 PF14389.1 ETO05753.1 - 0.54 10.4 8.7 0.36 10.9 3.6 2.3 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF4140 PF13600.1 ETO05753.1 - 1.7 9.1 6.8 0.21 12.0 0.6 2.5 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) TraV PF09676.5 ETO05754.1 - 0.034 14.8 0.1 0.054 14.2 0.0 1.2 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) DUF4582 PF15189.1 ETO05754.1 - 0.071 12.3 0.7 0.11 11.7 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4582) DUF3451 PF11933.3 ETO05754.1 - 0.093 12.5 4.3 0.14 11.9 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3451) Peptidase_M54 PF07998.6 ETO05755.1 - 0.0072 16.1 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M54 Red1 PF07964.6 ETO05755.1 - 6 4.8 7.2 0.1 10.7 0.3 1.4 2 0 0 2 2 2 0 Rec10 / Red1 Apo-CII PF05355.6 ETO05756.1 - 0.085 12.7 1.9 7.5 6.4 0.0 2.7 3 0 0 3 3 3 0 Apolipoprotein C-II Cnd2 PF05786.9 ETO05757.1 - 1.6e-94 317.9 25.0 1.1e-52 179.5 6.4 2.2 2 0 0 2 2 2 2 Condensin complex subunit 2 Myosin_tail_1 PF01576.14 ETO05758.1 - 0.0001 20.2 4.9 0.00015 19.7 3.4 1.3 1 0 0 1 1 1 1 Myosin tail APG17 PF04108.7 ETO05758.1 - 0.00018 20.4 2.4 0.00021 20.2 1.7 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 Lipoprotein_7 PF01540.11 ETO05758.1 - 0.00019 20.6 1.0 0.00019 20.6 0.7 1.1 1 0 0 1 1 1 1 Adhesin lipoprotein Fmp27_WPPW PF10359.4 ETO05758.1 - 0.0002 19.9 4.8 0.00026 19.5 3.3 1.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain V_ATPase_I PF01496.14 ETO05758.1 - 0.00034 18.6 3.4 0.00049 18.1 2.4 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family GAS PF13851.1 ETO05758.1 - 0.00051 19.3 10.3 0.0007 18.8 7.2 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DASH_Dad2 PF08654.5 ETO05758.1 - 0.0012 18.8 5.2 0.61 10.1 2.2 2.3 1 1 1 2 2 2 2 DASH complex subunit Dad2 DUF677 PF05055.7 ETO05758.1 - 0.0014 17.3 0.1 0.0018 16.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF677) DivIC PF04977.10 ETO05758.1 - 0.0023 17.3 10.5 0.008 15.6 4.2 2.5 1 1 1 2 2 2 1 Septum formation initiator UPF0118 PF01594.11 ETO05758.1 - 0.0023 16.9 2.3 0.084 11.8 0.1 2.0 1 1 1 2 2 2 1 Domain of unknown function DUF20 ALIX_LYPXL_bnd PF13949.1 ETO05758.1 - 0.0032 16.4 7.6 0.0054 15.7 5.3 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF3450 PF11932.3 ETO05758.1 - 0.0044 16.3 7.6 0.0044 16.3 5.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) APG6 PF04111.7 ETO05758.1 - 0.0048 15.9 5.5 0.0062 15.6 3.8 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 DUF342 PF03961.8 ETO05758.1 - 0.0053 15.2 2.2 0.0075 14.7 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF342) DUF869 PF05911.6 ETO05758.1 - 0.006 14.8 3.4 0.0071 14.6 2.4 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) Tropomyosin PF00261.15 ETO05758.1 - 0.0063 15.6 7.1 0.0084 15.2 4.9 1.1 1 0 0 1 1 1 1 Tropomyosin DUF2317 PF10079.4 ETO05758.1 - 0.0068 15.0 1.2 0.0084 14.7 0.9 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2317) PilJ PF13675.1 ETO05758.1 - 0.0083 16.4 3.0 0.17 12.2 1.6 2.1 1 1 1 2 2 2 2 Type IV pili methyl-accepting chemotaxis transducer N-term Mnd1 PF03962.10 ETO05758.1 - 0.0087 15.7 5.7 0.012 15.2 4.0 1.1 1 0 0 1 1 1 1 Mnd1 family YfhO PF09586.5 ETO05758.1 - 0.0087 14.1 0.2 0.012 13.7 0.1 1.1 1 0 0 1 1 1 1 Bacterial membrane protein YfhO CENP-F_leu_zip PF10473.4 ETO05758.1 - 0.0097 15.7 10.6 0.017 14.9 6.9 1.5 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.6 ETO05758.1 - 0.0097 15.7 7.3 0.014 15.2 5.1 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) IncA PF04156.9 ETO05758.1 - 0.012 15.1 8.4 0.012 15.1 5.8 1.8 1 1 0 1 1 1 0 IncA protein HAUS-augmin3 PF14932.1 ETO05758.1 - 0.014 14.5 7.3 0.019 14.1 5.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 AAA_27 PF13514.1 ETO05758.1 - 0.015 12.9 2.1 0.019 12.6 1.5 1.0 1 0 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 ETO05758.1 - 0.018 14.2 0.9 0.022 13.9 0.6 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF2570 PF10828.3 ETO05758.1 - 0.019 14.5 6.4 0.067 12.8 4.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) Not3 PF04065.10 ETO05758.1 - 0.02 14.1 7.4 0.026 13.7 5.1 1.1 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Laminin_II PF06009.7 ETO05758.1 - 0.023 14.4 9.3 0.049 13.3 6.3 1.6 1 1 0 1 1 1 0 Laminin Domain II FUN14 PF04930.10 ETO05758.1 - 0.024 14.9 3.2 0.079 13.2 2.2 1.9 1 1 0 1 1 1 0 FUN14 family SURF4 PF02077.10 ETO05758.1 - 0.024 14.0 2.5 3 7.1 0.8 2.2 2 0 0 2 2 2 0 SURF4 family DUF4600 PF15372.1 ETO05758.1 - 0.025 14.7 4.4 0.037 14.2 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) DUF935 PF06074.7 ETO05758.1 - 0.027 13.2 0.4 0.037 12.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Atg14 PF10186.4 ETO05758.1 - 0.03 13.2 5.2 0.04 12.8 3.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_32 PF13654.1 ETO05758.1 - 0.03 12.9 2.2 0.035 12.7 1.5 1.0 1 0 0 1 1 1 0 AAA domain DUF724 PF05266.9 ETO05758.1 - 0.035 13.7 6.4 0.034 13.7 3.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) HALZ PF02183.13 ETO05758.1 - 0.04 13.6 2.4 0.04 13.6 1.7 3.0 3 1 0 3 3 2 0 Homeobox associated leucine zipper DUF3584 PF12128.3 ETO05758.1 - 0.042 11.1 8.2 0.053 10.8 5.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TBPIP PF07106.8 ETO05758.1 - 0.043 13.3 11.6 0.059 12.9 7.7 1.4 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CbtB PF09489.5 ETO05758.1 - 0.047 13.6 3.6 0.064 13.1 1.4 2.0 1 1 1 2 2 1 0 Probable cobalt transporter subunit (CbtB) DUF4337 PF14235.1 ETO05758.1 - 0.051 13.4 5.5 0.053 13.3 3.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) DUF4131 PF13567.1 ETO05758.1 - 0.052 12.9 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DivIVA PF05103.8 ETO05758.1 - 0.052 13.6 11.1 0.55 10.2 6.4 2.0 1 1 1 2 2 2 0 DivIVA protein CALCOCO1 PF07888.6 ETO05758.1 - 0.059 11.6 6.6 0.077 11.2 4.6 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like EzrA PF06160.7 ETO05758.1 - 0.064 11.4 10.6 0.27 9.3 3.2 1.9 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA ADIP PF11559.3 ETO05758.1 - 0.065 13.1 7.5 0.11 12.4 5.2 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF2681 PF10883.3 ETO05758.1 - 0.065 13.4 1.9 0.33 11.1 1.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) Phage_GP20 PF06810.6 ETO05758.1 - 0.066 12.6 15.9 0.15 11.5 11.0 1.6 1 1 0 1 1 1 0 Phage minor structural protein GP20 DUF3007 PF11460.3 ETO05758.1 - 0.067 13.2 0.1 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) CCDC155 PF14662.1 ETO05758.1 - 0.078 12.5 8.4 0.12 11.9 5.4 1.4 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 Seryl_tRNA_N PF02403.17 ETO05758.1 - 0.085 12.8 11.4 0.084 12.8 6.7 1.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Corona_S2 PF01601.11 ETO05758.1 - 0.086 10.9 3.3 0.12 10.4 2.3 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein TPR_MLP1_2 PF07926.7 ETO05758.1 - 0.086 12.5 9.5 0.13 12.0 6.6 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Caldesmon PF02029.10 ETO05758.1 - 0.091 11.1 3.3 0.12 10.7 2.3 1.1 1 0 0 1 1 1 0 Caldesmon STAT_alpha PF01017.15 ETO05758.1 - 0.1 12.2 9.5 0.064 12.9 3.6 1.7 1 1 0 1 1 1 0 STAT protein, all-alpha domain RRF_GI PF12614.3 ETO05758.1 - 0.11 12.3 2.5 0.15 11.9 1.7 1.2 1 0 0 1 1 1 0 Ribosome recycling factor DUF3347 PF11827.3 ETO05758.1 - 0.11 12.4 2.8 0.15 12.0 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) AAA_13 PF13166.1 ETO05758.1 - 0.12 10.8 8.7 0.15 10.4 6.0 1.1 1 0 0 1 1 1 0 AAA domain DUF3373 PF11853.3 ETO05758.1 - 0.16 10.4 2.0 0.19 10.2 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF4446 PF14584.1 ETO05758.1 - 0.17 11.6 3.7 0.15 11.8 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) MCPsignal PF00015.16 ETO05758.1 - 0.18 11.3 4.0 0.17 11.4 1.1 1.8 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CAGE1 PF15066.1 ETO05758.1 - 0.22 9.9 10.5 0.28 9.5 7.3 1.1 1 0 0 1 1 1 0 Cancer-associated gene protein 1 family BLOC1_2 PF10046.4 ETO05758.1 - 0.22 11.6 12.4 0.16 12.1 5.7 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MscS_porin PF12795.2 ETO05758.1 - 0.23 10.7 10.0 0.32 10.2 6.9 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain FlgN PF05130.7 ETO05758.1 - 0.24 11.6 5.4 0.35 11.1 3.8 1.2 1 0 0 1 1 1 0 FlgN protein TMF_DNA_bd PF12329.3 ETO05758.1 - 0.25 11.1 13.3 0.59 9.9 9.1 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding zf-C4H2 PF10146.4 ETO05758.1 - 0.26 11.2 5.2 0.36 10.8 3.6 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein UPF0449 PF15136.1 ETO05758.1 - 0.28 11.4 3.0 0.51 10.5 0.6 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Peptidase_C65 PF10275.4 ETO05758.1 - 0.3 10.3 5.1 1.1 8.6 0.5 2.0 1 1 1 2 2 2 0 Peptidase C65 Otubain COMP PF11598.3 ETO05758.1 - 0.33 11.0 2.5 12 6.0 0.1 3.0 3 0 0 3 3 2 0 Cartilage oligomeric matrix protein bZIP_1 PF00170.16 ETO05758.1 - 0.35 10.8 9.0 0.096 12.6 2.3 2.4 1 1 2 3 3 3 0 bZIP transcription factor Syntaxin-6_N PF09177.6 ETO05758.1 - 0.44 10.9 7.0 0.67 10.4 2.6 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Spc7 PF08317.6 ETO05758.1 - 0.49 9.0 13.9 0.4 9.3 3.4 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF812 PF05667.6 ETO05758.1 - 0.57 8.6 11.1 1 7.8 7.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Ax_dynein_light PF10211.4 ETO05758.1 - 0.63 9.8 10.0 0.83 9.4 6.4 1.6 1 1 0 1 1 1 0 Axonemal dynein light chain DUF1664 PF07889.7 ETO05758.1 - 0.67 9.7 9.5 0.76 9.5 4.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Prefoldin PF02996.12 ETO05758.1 - 0.9 9.1 9.7 1.9 8.1 3.6 2.4 1 1 2 3 3 3 0 Prefoldin subunit TMPIT PF07851.8 ETO05758.1 - 0.91 8.5 12.1 0.021 13.8 3.9 1.5 2 0 0 2 2 1 0 TMPIT-like protein DUF2968 PF11180.3 ETO05758.1 - 0.95 8.8 4.8 0.69 9.2 1.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) Prefoldin_2 PF01920.15 ETO05758.1 - 1.2 8.9 12.0 4.2 7.1 3.4 2.2 1 1 1 2 2 2 0 Prefoldin subunit Fib_alpha PF08702.5 ETO05758.1 - 1.2 9.1 10.0 7.9 6.6 6.7 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.6 ETO05758.1 - 1.4 8.8 9.9 2.4 8.1 4.5 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Med9 PF07544.8 ETO05758.1 - 1.5 8.6 5.8 23 4.8 4.0 2.3 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Drf_FH3 PF06367.11 ETO05758.1 - 1.6 8.0 12.6 0.29 10.5 1.7 2.2 1 1 1 2 2 2 0 Diaphanous FH3 Domain SlyX PF04102.7 ETO05758.1 - 1.7 9.0 6.0 9 6.7 1.5 2.3 1 1 1 2 2 2 0 SlyX DUF904 PF06005.7 ETO05758.1 - 1.7 8.9 10.3 4.8 7.5 7.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF904) NPV_P10 PF05531.7 ETO05758.1 - 1.9 8.8 10.5 37 4.6 7.3 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein CENP-Q PF13094.1 ETO05758.1 - 2.2 8.2 11.1 6.8 6.6 7.7 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Sec20 PF03908.8 ETO05758.1 - 2.6 7.8 6.6 27 4.5 2.3 2.5 1 1 1 2 2 2 0 Sec20 DUF972 PF06156.8 ETO05758.1 - 2.8 8.3 9.8 16 5.8 6.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF972) YtxH PF12732.2 ETO05758.1 - 4.2 7.8 7.3 13 6.2 5.0 2.0 1 1 0 1 1 1 0 YtxH-like protein CCDC-167 PF15188.1 ETO05758.1 - 4.2 7.3 9.3 31 4.5 6.4 2.2 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Bap31 PF05529.7 ETO05758.1 - 4.9 6.5 9.3 6.7 6.1 6.3 1.4 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like TSC22 PF01166.13 ETO05758.1 - 5 7.1 7.4 14 5.7 0.9 2.5 1 1 1 2 2 2 0 TSC-22/dip/bun family FlxA PF14282.1 ETO05758.1 - 6.5 6.7 12.9 20 5.2 8.9 1.8 1 1 0 1 1 1 0 FlxA-like protein DUF948 PF06103.6 ETO05758.1 - 7.9 6.4 12.3 0.72 9.7 2.4 3.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Tup_N PF08581.5 ETO05758.1 - 9.1 6.5 11.6 5.6 7.2 0.4 2.2 1 1 1 2 2 2 0 Tup N-terminal Kinesin PF00225.18 ETO05759.1 - 6e-20 71.2 0.3 4.8e-13 48.5 0.0 3.0 1 1 2 3 3 3 3 Kinesin motor domain DUF3638 PF12340.3 ETO05759.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) TPR_19 PF14559.1 ETO05760.1 - 1.6e-09 37.9 7.9 0.00014 22.1 0.2 4.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO05760.1 - 2e-05 24.4 0.6 3.4 8.1 0.0 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO05760.1 - 4.1e-05 23.1 9.4 0.00016 21.2 0.1 4.7 5 0 0 5 5 5 1 TPR repeat TPR_14 PF13428.1 ETO05760.1 - 4.2e-05 23.8 3.2 0.6 10.9 0.2 5.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO05760.1 - 8.6e-05 23.1 4.3 0.0067 17.0 0.4 3.7 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO05760.1 - 0.00012 21.5 0.8 1.4 8.8 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETO05760.1 - 0.0032 17.2 0.2 0.011 15.6 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO05760.1 - 0.0064 16.0 0.0 0.0064 16.0 0.0 4.3 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_20 PF14561.1 ETO05760.1 - 0.013 15.5 6.2 2.1 8.5 0.0 4.6 3 2 1 4 4 4 0 Tetratricopeptide repeat CobT PF06213.7 ETO05760.1 - 0.052 12.6 8.2 0.11 11.6 5.7 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TPR_2 PF07719.12 ETO05760.1 - 0.052 13.4 8.4 0.11 12.4 0.0 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TraG_N PF07916.6 ETO05760.1 - 0.056 11.8 0.3 0.091 11.1 0.2 1.4 1 0 0 1 1 1 0 TraG-like protein, N-terminal region TPR_12 PF13424.1 ETO05760.1 - 0.077 12.9 0.1 0.077 12.9 0.0 4.4 6 0 0 6 6 5 0 Tetratricopeptide repeat Orbi_VP6 PF01516.11 ETO05760.1 - 0.12 11.4 11.3 0.18 10.8 7.8 1.3 1 0 0 1 1 1 0 Orbivirus helicase VP6 DUF3484 PF11983.3 ETO05760.1 - 0.61 10.9 0.1 0.61 10.9 0.1 3.0 2 1 1 3 3 2 0 Domain of unknown function (DUF3484) TRAP_alpha PF03896.11 ETO05760.1 - 1.3 7.9 7.9 2.2 7.2 5.5 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit zf-DHHC PF01529.15 ETO05760.1 - 1.6 8.0 9.0 1.6 8.1 0.8 2.6 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF4175 PF13779.1 ETO05760.1 - 2.4 5.7 18.4 3.8 5.1 12.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF2052 PF09747.4 ETO05760.1 - 2.7 7.8 20.6 0.95 9.3 10.5 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF2360 PF10152.4 ETO05760.1 - 6.1 7.1 12.1 2.1 8.6 5.1 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Pep_deformylase PF01327.16 ETO05761.1 - 1.5e-29 102.3 0.0 1.8e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase GDI PF00996.13 ETO05763.1 - 9.3e-12 43.9 0.8 1.4e-11 43.3 0.4 1.4 1 1 0 1 1 1 1 GDP dissociation inhibitor DUF4613 PF15390.1 ETO05763.1 - 0.1 10.7 0.4 0.11 10.6 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Ank_2 PF12796.2 ETO05764.1 - 0.11 12.8 0.0 0.34 11.2 0.0 1.8 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) Pico_P2B PF01552.12 ETO05765.1 - 0.51 10.5 2.5 3.1 7.9 0.1 2.7 3 0 0 3 3 3 0 Picornavirus 2B protein DUF2870 PF11069.3 ETO05768.1 - 1.9e-21 75.9 0.5 5.8e-21 74.3 0.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) WD40 PF00400.27 ETO05769.1 - 0.0027 17.5 0.2 0.032 14.1 0.0 2.1 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF2721 PF11026.3 ETO05769.1 - 0.021 14.4 0.0 0.028 14.0 0.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2721) SAB PF04382.8 ETO05769.1 - 0.099 12.3 3.6 0.16 11.6 2.5 1.3 1 0 0 1 1 1 0 SAB domain Poty_PP PF08440.5 ETO05770.1 - 0.036 13.1 1.7 0.04 12.9 1.2 1.1 1 0 0 1 1 1 0 Potyviridae polyprotein Apc15p PF05841.6 ETO05770.1 - 5 7.8 14.6 6.7 7.4 1.8 2.1 1 1 1 2 2 2 0 Apc15p protein MTTB PF06253.6 ETO05772.1 - 0.039 11.7 0.0 0.051 11.3 0.0 1.2 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) DUF2120 PF09893.4 ETO05772.1 - 0.092 12.6 1.5 0.14 12.1 0.3 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) Rota_NSP4 PF01452.11 ETO05772.1 - 1.3 8.3 6.4 8.5 5.6 0.3 3.0 2 1 0 3 3 3 0 Rotavirus non structural protein Miro PF08477.8 ETO05773.1 - 2.2e-12 47.5 0.1 5.6e-12 46.2 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Ras PF00071.17 ETO05773.1 - 2.9e-11 43.0 1.2 1.1e-10 41.1 0.2 2.4 1 1 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 ETO05773.1 - 0.0029 17.5 0.1 0.0056 16.6 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 ETO05773.1 - 0.0066 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Septin PF00735.13 ETO05773.1 - 0.01 14.8 0.0 0.017 14.1 0.0 1.5 1 0 0 1 1 1 0 Septin AAA_22 PF13401.1 ETO05773.1 - 0.013 15.6 0.0 0.043 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 ETO05773.1 - 0.018 14.4 1.5 0.26 10.6 0.8 2.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 ETO05773.1 - 0.083 12.7 0.6 0.64 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Tetraspannin PF00335.15 ETO05774.1 - 1.8e-09 37.2 13.1 3.4e-09 36.3 9.1 1.5 1 0 0 1 1 1 1 Tetraspanin family Sigma_reg_N PF13800.1 ETO05774.1 - 1.5 8.9 9.0 0.49 10.4 1.4 3.1 2 2 1 3 3 3 0 Sigma factor regulator N-terminal DUF4149 PF13664.1 ETO05774.1 - 8.4 6.5 11.8 24 5.0 5.5 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) DUF1664 PF07889.7 ETO05775.1 - 4.9 6.9 19.1 0.74 9.6 7.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Peptidase_S46 PF10459.4 ETO05775.1 - 6.5 5.0 16.5 9.1 4.5 11.5 1.1 1 0 0 1 1 1 0 Peptidase S46 WXG100 PF06013.7 ETO05775.1 - 8.7 6.4 11.0 3 7.9 1.2 2.5 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Kelch_1 PF01344.20 ETO05776.1 - 2.3e-08 33.4 0.6 7.2e-05 22.2 0.2 3.9 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 ETO05776.1 - 7.9e-08 32.0 1.0 0.011 15.6 0.4 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO05776.1 - 2.5e-07 30.5 2.1 0.00052 20.0 0.2 3.7 2 1 1 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO05776.1 - 2.9e-07 29.9 0.8 0.035 13.8 0.1 3.9 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.1 ETO05776.1 - 2.1e-06 27.4 0.3 0.0034 17.1 0.0 3.5 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO05776.1 - 0.016 15.3 0.0 0.2 11.8 0.0 2.7 2 0 0 2 2 2 0 Galactose oxidase, central domain PUB PF09409.5 ETO05777.1 - 0.016 14.9 2.2 0.052 13.2 1.2 1.9 1 1 1 2 2 2 0 PUB domain Cut8_C PF08559.5 ETO05777.1 - 0.029 14.1 0.1 0.032 14.0 0.1 1.1 1 0 0 1 1 1 0 Cut8 six-helix bundle DUF3135 PF11333.3 ETO05778.1 - 0.085 13.0 0.5 0.18 11.9 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) TFIID-18kDa PF02269.11 ETO05779.1 - 0.0018 18.0 0.5 0.0028 17.4 0.3 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Ribosomal_L5_C PF00673.16 ETO05779.1 - 0.06 13.0 0.5 0.094 12.4 0.3 1.4 1 0 0 1 1 1 0 ribosomal L5P family C-terminus CLN5 PF15014.1 ETO05779.1 - 0.084 12.2 1.4 0.095 12.0 0.9 1.1 1 0 0 1 1 1 0 Ceroid-lipofuscinosis neuronal protein 5 Cas_APE2256 PF09651.5 ETO05782.1 - 0.011 15.3 0.1 3.1 7.5 0.0 2.2 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_APE2256) VHS PF00790.14 ETO05782.1 - 0.066 12.8 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 VHS domain IBR PF01485.16 ETO05782.1 - 0.48 10.3 3.7 1.5 8.7 2.6 1.9 1 1 0 1 1 1 0 IBR domain CAF1 PF04857.15 ETO05783.1 - 0.058 12.7 1.0 0.076 12.3 0.6 1.2 1 1 0 1 1 1 0 CAF1 family ribonuclease Adeno_E3_CR1 PF02440.10 ETO05784.1 - 0.13 11.7 1.3 0.24 10.8 0.5 1.7 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 Sigma54_DBD PF04552.8 ETO05785.1 - 0.025 14.0 0.5 0.037 13.5 0.1 1.6 2 0 0 2 2 2 0 Sigma-54, DNA binding domain Pox_Ag35 PF03286.9 ETO05786.1 - 1.7 8.1 14.5 1.7 8.1 10.0 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein bZIP_Maf PF03131.12 ETO05786.1 - 2.9 8.2 12.3 2.7 8.3 8.0 1.4 1 1 0 1 1 1 0 bZIP Maf transcription factor FLO_LFY PF01698.11 ETO05786.1 - 3.7 6.2 11.5 3.8 6.2 7.9 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein PPP1R35_C PF15503.1 ETO05787.1 - 0.049 13.1 0.0 0.07 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 35 C-terminus Cnd1 PF12717.2 ETO05788.1 - 0.0003 20.7 1.0 0.14 11.9 0.0 2.7 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.5 ETO05788.1 - 0.0044 16.6 0.8 0.094 12.2 0.2 2.5 2 1 0 2 2 2 1 TATA-binding protein interacting (TIP20) PPP1R35_C PF15503.1 ETO05788.1 - 0.031 13.7 2.4 0.034 13.6 0.3 1.9 2 0 0 2 2 2 0 Protein phosphatase 1 regulatory subunit 35 C-terminus Ecm29 PF13001.2 ETO05788.1 - 0.031 12.7 2.0 0.11 11.0 0.9 1.9 1 1 1 2 2 2 0 Proteasome stabiliser HsdM_N PF12161.3 ETO05788.1 - 0.043 14.2 1.8 0.063 13.6 0.4 1.9 1 1 1 2 2 2 0 HsdM N-terminal domain HEAT PF02985.17 ETO05788.1 - 0.049 13.7 0.0 0.48 10.6 0.0 2.4 2 0 0 2 2 2 0 HEAT repeat LLGL PF08366.8 ETO05788.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.5 1 1 0 1 1 1 0 LLGL2 SET_assoc PF11767.3 ETO05788.1 - 0.12 11.7 0.3 0.3 10.4 0.2 1.7 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Lip_prot_lig_C PF10437.4 ETO05788.1 - 0.15 11.7 2.4 1.8 8.3 0.1 2.6 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus Atrophin-1 PF03154.10 ETO05790.1 - 0.2 9.7 2.4 0.21 9.6 1.6 1.0 1 0 0 1 1 1 0 Atrophin-1 family Vfa1 PF08432.5 ETO05790.1 - 6.3 6.7 15.3 1.6 8.7 8.4 1.5 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 GRASP55_65 PF04495.9 ETO05792.1 - 0.031 14.2 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain CPSase_L_D3 PF02787.14 ETO05793.1 - 0.024 14.3 8.0 0.06 13.1 1.6 3.4 3 1 0 3 3 3 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ApbE PF02424.10 ETO05793.1 - 0.24 10.6 1.1 0.8 8.9 0.1 2.1 2 0 0 2 2 2 0 ApbE family ArsC PF03960.10 ETO05793.1 - 0.4 10.7 9.8 0.16 12.0 0.6 3.3 2 1 0 2 2 2 0 ArsC family HJURP_C PF12347.3 ETO05793.1 - 0.53 9.8 8.3 2.5 7.7 0.6 3.1 2 1 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat DUF964 PF06133.6 ETO05793.1 - 4.8 7.2 19.3 0.67 9.9 5.7 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF964) HSDR_N_2 PF13588.1 ETO05794.1 - 0.017 14.8 0.1 0.035 13.8 0.1 1.6 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) U-box PF04564.10 ETO05795.1 - 5.8e-08 32.5 0.0 2.4e-07 30.5 0.0 2.2 1 1 0 1 1 1 1 U-box domain Kelch_6 PF13964.1 ETO05795.1 - 1e-06 28.6 9.1 0.0025 17.8 0.0 4.5 4 2 1 5 5 5 2 Kelch motif zf-U1 PF06220.7 ETO05795.1 - 4.3e-05 22.9 0.6 4.3e-05 22.9 0.4 2.1 2 0 0 2 2 2 1 U1 zinc finger Kelch_3 PF13415.1 ETO05795.1 - 0.00099 19.2 0.0 0.24 11.6 0.0 2.9 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO05795.1 - 0.014 14.9 3.9 0.47 10.0 0.1 3.2 3 0 0 3 3 3 0 Kelch motif Rtt102p PF09510.5 ETO05795.1 - 0.021 14.8 1.2 0.021 14.8 0.8 2.9 2 1 1 3 3 3 0 Rtt102p-like transcription regulator protein TAF8_C PF10406.4 ETO05795.1 - 0.42 10.7 3.9 1.8 8.7 0.0 2.9 3 0 0 3 3 3 0 Transcription factor TFIID complex subunit 8 C-term TMCO5 PF14992.1 ETO05796.1 - 0.00022 20.4 10.6 0.00022 20.4 7.3 1.6 2 0 0 2 2 2 1 TMCO5 family IncA PF04156.9 ETO05796.1 - 0.0017 17.9 9.8 0.0042 16.7 6.8 1.7 1 1 0 1 1 1 1 IncA protein DUF869 PF05911.6 ETO05796.1 - 0.0021 16.3 7.7 0.0025 16.1 5.3 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) Ax_dynein_light PF10211.4 ETO05796.1 - 0.0035 17.2 4.5 0.0035 17.2 3.1 2.2 1 1 1 2 2 2 1 Axonemal dynein light chain ING PF12998.2 ETO05796.1 - 0.0098 16.1 10.4 0.023 14.9 7.2 1.7 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding SICA_beta PF12878.2 ETO05796.1 - 0.012 15.3 0.2 0.012 15.3 0.1 2.3 1 1 1 2 2 2 0 SICA extracellular beta domain ATG16 PF08614.6 ETO05796.1 - 0.037 13.8 10.0 0.074 12.8 7.0 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 ETO05796.1 - 0.051 13.4 14.0 0.13 12.1 1.2 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF489 PF04356.7 ETO05796.1 - 0.077 12.5 1.4 0.11 12.0 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF489) APG6 PF04111.7 ETO05796.1 - 0.083 11.9 12.5 0.16 11.0 8.6 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 Myosin_tail_1 PF01576.14 ETO05796.1 - 0.098 10.3 15.6 0.24 9.0 10.2 1.7 1 1 0 1 1 1 0 Myosin tail NPV_P10 PF05531.7 ETO05796.1 - 0.13 12.5 6.0 0.54 10.5 1.4 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.10 ETO05796.1 - 0.19 11.2 11.0 2 7.9 1.0 2.7 2 0 0 2 2 2 0 Septum formation initiator Laminin_II PF06009.7 ETO05796.1 - 0.25 11.0 7.2 0.56 9.9 4.1 2.0 1 1 1 2 2 2 0 Laminin Domain II Spc7 PF08317.6 ETO05796.1 - 0.56 8.8 16.4 1.1 7.8 11.4 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.7 ETO05796.1 - 0.86 9.4 9.8 1.1 9.0 2.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GAS PF13851.1 ETO05796.1 - 1.2 8.3 21.4 4.4 6.4 14.2 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Cauli_DNA-bind PF03310.8 ETO05796.1 - 1.6 8.6 7.1 0.37 10.6 2.6 1.7 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein Exonuc_VII_L PF02601.10 ETO05796.1 - 1.8 7.6 7.5 2.6 7.1 5.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.14 ETO05796.1 - 2.3 5.9 11.4 1.6 6.4 6.9 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family MutS_IV PF05190.13 ETO05796.1 - 2.8 8.1 10.0 8 6.7 0.9 3.1 1 1 3 4 4 4 0 MutS family domain IV DUF972 PF06156.8 ETO05796.1 - 3 8.2 12.7 50 4.2 8.8 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Seryl_tRNA_N PF02403.17 ETO05796.1 - 3.5 7.6 13.1 11 6.1 8.7 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4164 PF13747.1 ETO05796.1 - 3.9 7.6 9.5 17 5.5 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DUF607 PF04678.8 ETO05796.1 - 4.7 7.1 6.4 0.96 9.3 1.4 1.9 1 1 1 2 2 2 0 Protein of unknown function, DUF607 ATP-synt_G PF04718.10 ETO05799.1 - 0.0033 18.0 0.1 0.005 17.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit Pkinase PF00069.20 ETO05800.1 - 2.2e-70 236.7 0.8 3.7e-70 236.0 0.6 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO05800.1 - 1.1e-28 100.0 1.5 5.6e-28 97.7 1.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO05800.1 - 0.00061 18.8 1.0 0.0012 17.8 0.7 1.6 1 1 0 1 1 1 1 Kinase-like WD40 PF00400.27 ETO05801.1 - 1.9e-14 52.8 1.7 2.3e-08 33.5 0.2 2.6 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO05801.1 - 0.0001 20.5 0.3 0.012 13.8 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO05801.1 - 0.031 13.0 0.9 2.2 6.9 0.1 2.0 1 1 1 2 2 2 0 Nup133 N terminal like DUF192 PF02643.10 ETO05802.1 - 0.13 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized ACR, COG1430 LpxD PF04613.9 ETO05803.1 - 0.041 13.4 0.1 0.069 12.6 0.1 1.3 1 0 0 1 1 1 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD Beta_helix PF13229.1 ETO05803.1 - 1.5 8.5 19.3 7.3 6.3 13.4 2.0 1 1 0 1 1 1 0 Right handed beta helix region Kelch_6 PF13964.1 ETO05804.1 - 0.058 13.6 0.0 0.45 10.7 0.0 2.2 2 0 0 2 2 2 0 Kelch motif Copper-bind PF00127.15 ETO05804.1 - 0.086 13.0 0.4 0.18 12.0 0.3 1.6 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family VWA_3 PF13768.1 ETO05805.1 - 0.051 13.2 0.0 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 von Willebrand factor type A domain WD40 PF00400.27 ETO05806.1 - 6.5e-62 203.3 19.4 1.3e-10 40.7 0.2 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO05806.1 - 4.8e-11 41.5 2.1 0.033 12.3 0.1 5.8 3 2 2 5 5 5 5 Nucleoporin Nup120/160 HAD PF12710.2 ETO05806.1 - 0.15 12.1 5.0 1.8 8.7 1.5 2.9 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase ECIST_Cterm PF14784.1 ETO05809.1 - 0.012 15.5 3.5 0.014 15.3 0.7 2.3 2 0 0 2 2 2 0 C-terminal domain of the ECSIT protein zf-LITAF-like PF10601.4 ETO05809.1 - 0.024 14.4 0.1 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain DUF3484 PF11983.3 ETO05809.1 - 0.085 13.7 4.8 0.072 13.9 1.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3484) PspA_IM30 PF04012.7 ETO05809.1 - 0.3 10.3 9.6 0.036 13.4 2.9 2.0 2 0 0 2 2 2 0 PspA/IM30 family RRM_1 PF00076.17 ETO05810.1 - 5.3e-11 41.9 0.0 9.4e-11 41.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO05810.1 - 4.6e-08 32.9 0.1 8.7e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO05810.1 - 1.6e-05 24.6 0.1 3e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CRAM_rpt PF07016.6 ETO05810.1 - 0.001 18.3 0.7 8.1 5.8 0.0 3.6 3 0 0 3 3 3 2 Cysteine-rich acidic integral membrane protein precursor Chorion_1 PF01723.11 ETO05810.1 - 0.0021 17.9 0.8 0.14 12.0 0.1 2.2 1 1 1 2 2 2 2 Chorion protein DUF89 PF01937.14 ETO05812.1 - 0.019 13.7 0.4 0.022 13.5 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF89 Peptidase_S49_N PF08496.5 ETO05812.1 - 3.2 7.5 5.6 3.7 7.3 3.9 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal BLVR PF06375.6 ETO05812.1 - 3.3 7.5 7.9 3.5 7.4 5.5 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) DUF912 PF06024.7 ETO05813.1 - 0.52 10.3 5.3 1.1 9.3 3.7 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Med25_NR-box PF11244.3 ETO05813.1 - 0.76 10.2 15.7 0.081 13.3 4.9 2.6 2 0 0 2 2 2 0 Mediator complex subunit 25 C-terminal NR box-containing Methyltransf_12 PF08242.7 ETO05814.1 - 0.00086 19.7 0.1 1.6 9.2 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 ETO05814.1 - 0.0015 18.9 0.0 0.09 13.2 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETO05814.1 - 0.0063 16.2 0.1 0.048 13.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO05814.1 - 0.0064 17.0 0.0 0.037 14.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETO05814.1 - 0.029 14.7 0.1 15 6.0 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain zf-BED PF02892.10 ETO05814.1 - 0.47 10.2 7.4 0.046 13.4 1.3 2.2 2 0 0 2 2 2 0 BED zinc finger WD40 PF00400.27 ETO05815.1 - 6.8e-46 152.5 22.5 6e-12 44.9 1.3 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO05815.1 - 4.3e-10 38.3 4.2 0.0035 15.5 0.0 4.4 2 2 3 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO05815.1 - 0.00024 19.9 3.3 2 7.0 0.2 4.2 2 1 1 4 4 4 2 Nup133 N terminal like DUF1900 PF08954.6 ETO05815.1 - 0.0034 16.9 0.1 6.7 6.2 0.0 3.3 2 1 2 4 4 4 2 Domain of unknown function (DUF1900) DUF1618 PF07762.9 ETO05815.1 - 0.036 14.2 0.4 0.2 11.8 0.0 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1618) PQQ_3 PF13570.1 ETO05815.1 - 0.068 13.4 0.5 63 4.0 0.0 4.1 4 0 0 4 4 4 0 PQQ-like domain SUKH_5 PF14567.1 ETO05815.1 - 0.12 11.8 0.2 25 4.3 0.0 3.5 3 1 0 3 3 3 0 SMI1-KNR4 cell-wall WD40 PF00400.27 ETO05816.1 - 1.9e-22 78.2 14.0 3.2e-11 42.6 0.1 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat Metallothi_Euk2 PF12809.2 ETO05816.1 - 0.46 10.9 3.2 3.4 8.1 0.3 2.4 2 1 1 3 3 3 0 Eukaryotic metallothionein LicD PF04991.8 ETO05817.1 - 1.4e-05 25.3 0.2 2.6e-05 24.4 0.2 1.5 1 0 0 1 1 1 1 LicD family HTH_7 PF02796.10 ETO05818.1 - 0.0027 17.5 0.1 0.0082 15.9 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase DsrC PF04358.8 ETO05818.1 - 0.044 14.0 0.5 0.044 14.0 0.4 2.6 2 2 1 3 3 3 0 DsrC like protein zf-BED PF02892.10 ETO05818.1 - 2.3 8.0 8.5 1.2 8.9 0.7 3.4 3 0 0 3 3 3 0 BED zinc finger Microtub_bind PF13931.1 ETO05819.1 - 1.3 9.1 5.8 0.72 9.9 2.0 2.0 2 0 0 2 2 2 0 Kinesin-associated microtubule-binding DUF1237 PF06824.6 ETO05820.1 - 0.026 13.1 0.7 0.03 12.9 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1237) DUF2722 PF10846.3 ETO05820.1 - 0.034 13.1 4.2 0.047 12.7 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Pkinase PF00069.20 ETO05821.1 - 0.0005 19.2 0.0 0.00056 19.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF3926 PF13080.1 ETO05823.1 - 0.082 12.4 0.1 0.2 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3926) Copper-bind PF00127.15 ETO05823.1 - 0.14 12.4 1.2 0.15 12.2 0.1 1.6 2 0 0 2 2 2 0 Copper binding proteins, plastocyanin/azurin family Raptor_N PF14538.1 ETO05825.1 - 0.0017 18.2 5.3 0.0032 17.3 3.6 1.5 1 1 0 1 1 1 1 Raptor N-terminal CASPase like domain YejG PF13989.1 ETO05825.1 - 0.44 10.6 4.5 0.73 9.9 1.6 2.1 1 1 1 2 2 2 0 YejG-like protein POT1 PF02765.12 ETO05825.1 - 5.2 6.9 8.7 0.39 10.6 1.0 2.4 1 1 0 2 2 2 0 Telomeric single stranded DNA binding POT1/CDC13 Arena_glycoprot PF00798.13 ETO05827.1 - 0.039 12.3 10.8 0.049 12.0 7.5 1.1 1 0 0 1 1 1 0 Arenavirus glycoprotein DUF4228 PF14009.1 ETO05827.1 - 2.9 8.0 8.3 0.4 10.8 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) Receptor_2B4 PF11465.3 ETO05827.1 - 7.2 6.5 11.0 0.6 10.0 0.8 3.1 2 1 1 3 3 3 0 Natural killer cell receptor 2B4 DUF167 PF02594.11 ETO05828.1 - 0.025 14.4 0.1 0.046 13.6 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised ACR, YggU family COG1872 DUF4365 PF14280.1 ETO05828.1 - 0.67 9.6 3.5 5.1 6.8 2.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4365) Ank_5 PF13857.1 ETO05829.1 - 1.8e-07 31.1 0.2 4.3e-07 29.9 0.1 1.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO05829.1 - 2.5e-07 30.9 0.2 1.7e-06 28.2 0.1 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO05829.1 - 6.3e-07 29.0 0.2 1.2e-05 25.0 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.25 ETO05829.1 - 3.4e-05 23.4 0.1 0.00019 21.0 0.0 2.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 ETO05829.1 - 8.5e-05 22.9 0.3 0.00017 22.0 0.1 1.5 1 1 0 1 1 1 1 Ankyrin repeats (many copies) HATPase_c_3 PF13589.1 ETO05830.1 - 4.3e-12 45.8 1.2 4.4e-12 45.8 0.8 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 ETO05830.1 - 1.3e-09 37.7 0.2 1.7e-09 37.3 0.1 1.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Gemini_AL1 PF00799.15 ETO05831.1 - 0.0076 16.0 0.1 0.018 14.8 0.1 1.7 1 0 0 1 1 1 1 Geminivirus Rep catalytic domain FbpA PF05833.6 ETO05832.1 - 1.2e-05 24.0 0.1 2.5e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Gemini_AL1 PF00799.15 ETO05832.1 - 0.01 15.6 0.0 0.04 13.7 0.0 2.1 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain HpaB PF03241.8 ETO05832.1 - 0.079 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal Pex24p PF06398.6 ETO05833.1 - 0.049 12.4 0.1 0.07 11.9 0.0 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin RNA_pol_Rpb2_4 PF04566.8 ETO05833.1 - 0.31 10.8 3.9 4.3 7.2 0.1 2.9 2 1 1 3 3 3 0 RNA polymerase Rpb2, domain 4 Tox-ART-HYE1 PF15634.1 ETO05833.1 - 0.44 9.4 4.1 0.66 8.8 0.1 2.0 2 0 0 2 2 2 0 HYE1 signature containing ADP-ribosyltransferase Tmemb_9 PF05434.6 ETO05833.1 - 2.4 7.8 5.8 3.8 7.2 4.0 1.5 1 1 0 1 1 1 0 TMEM9 Catalase PF00199.14 ETO05836.1 - 0.0034 16.1 0.2 0.0041 15.8 0.2 1.1 1 0 0 1 1 1 1 Catalase Suf PF05843.9 ETO05836.1 - 0.25 11.0 3.5 0.34 10.5 2.4 1.3 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) Mucin PF01456.12 ETO05837.1 - 0.032 14.0 17.7 0.044 13.5 12.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.7 ETO05837.1 - 0.84 7.3 5.5 0.98 7.0 3.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RecO_C PF02565.10 ETO05838.1 - 0.057 13.2 0.5 0.085 12.7 0.3 1.2 1 0 0 1 1 1 0 Recombination protein O C terminal DUF3865 PF12981.2 ETO05838.1 - 0.058 13.1 0.1 0.063 13.0 0.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3865) Arf PF00025.16 ETO05841.1 - 3.8e-15 55.5 5.6 1.1e-13 50.7 0.1 3.8 2 2 1 3 3 3 1 ADP-ribosylation factor family Potyvirid-P3 PF13608.1 ETO05841.1 - 0.0018 17.5 1.3 0.0018 17.5 0.9 3.1 3 0 0 3 3 3 1 Protein P3 of Potyviral polyprotein TMEM213 PF15192.1 ETO05841.1 - 0.057 13.4 0.1 0.2 11.6 0.0 1.9 1 0 0 1 1 1 0 TMEM213 family DUF1980 PF09323.5 ETO05842.1 - 0.1 12.3 0.4 0.41 10.3 0.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Neur_chan_memb PF02932.11 ETO05842.1 - 5.5 6.7 8.7 4.2 7.1 0.5 2.5 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PPR PF01535.15 ETO05843.1 - 8.7e-17 59.8 4.4 2.7e-05 23.8 0.0 4.6 4 0 0 4 4 4 4 PPR repeat PPR_2 PF13041.1 ETO05843.1 - 1.6e-16 60.0 16.5 1.8e-10 40.5 0.6 4.4 2 1 3 5 5 5 4 PPR repeat family PPR_3 PF13812.1 ETO05843.1 - 1e-15 56.5 0.0 1.5e-05 24.8 0.0 4.8 5 0 0 5 5 5 3 Pentatricopeptide repeat domain PPR_1 PF12854.2 ETO05843.1 - 1.7e-11 43.3 3.4 9.7e-05 21.7 0.0 4.6 5 0 0 5 5 5 3 PPR repeat DUF3636 PF12331.3 ETO05843.1 - 0.065 12.8 0.2 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3636) Rep_fac-A_C PF08646.5 ETO05845.1 - 8.2e-16 58.0 0.0 4.7e-15 55.5 0.0 1.9 2 0 0 2 2 2 1 Replication factor-A C terminal domain LRR_8 PF13855.1 ETO05845.1 - 0.00095 18.8 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 Leucine rich repeat tRNA_anti-codon PF01336.20 ETO05845.1 - 0.0068 16.2 0.0 0.026 14.3 0.0 2.0 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Lectin_leg-like PF03388.8 ETO05846.1 - 2.8e-24 85.5 0.7 3.7e-13 49.1 0.0 2.1 1 1 1 2 2 2 2 Legume-like lectin family Mito_carr PF00153.22 ETO05847.1 - 2.1e-19 69.0 8.2 2.4e-15 56.0 1.1 4.5 2 1 1 3 3 3 2 Mitochondrial carrier protein Wzz PF02706.10 ETO05847.1 - 0.077 12.8 1.0 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 Chain length determinant protein Maf1 PF09174.5 ETO05847.1 - 0.13 12.0 1.7 0.19 11.5 0.1 2.0 2 0 0 2 2 2 0 Maf1 regulator Acetyltransf_10 PF13673.1 ETO05848.1 - 0.029 14.4 0.0 0.038 14.1 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETO05848.1 - 0.032 14.2 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETO05848.1 - 0.05 13.7 0.0 0.082 13.0 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETO05848.1 - 0.053 13.3 0.0 4 7.2 0.0 2.4 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain DSPc PF00782.15 ETO05849.1 - 2.4e-28 98.3 0.1 6.1e-28 97.0 0.1 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 ETO05849.1 - 9.3e-13 48.5 0.0 1.1e-11 45.0 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain PTPlike_phytase PF14566.1 ETO05849.1 - 1.9e-06 27.9 0.0 4.8e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 Inositol hexakisphosphate Init_tRNA_PT PF04179.7 ETO05849.1 - 1.1e-05 24.5 0.5 3.1e-05 23.0 0.2 1.9 1 1 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase2 PF03162.8 ETO05849.1 - 0.0023 17.2 0.4 0.0059 15.9 0.1 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 ETO05849.1 - 0.0026 17.1 0.4 0.0055 16.0 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase WD40 PF00400.27 ETO05850.1 - 9.6e-59 193.3 20.0 8.5e-11 41.3 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO05850.1 - 1e-12 46.9 5.3 0.0087 14.2 0.3 4.5 2 1 3 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO05850.1 - 5.3e-06 26.2 6.3 0.013 15.2 0.2 4.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A BBS2_N PF14781.1 ETO05850.1 - 0.0061 16.1 0.7 0.3 10.7 0.0 3.3 2 1 2 4 4 4 1 Ciliary BBSome complex subunit 2, N-terminal DUF2099 PF09872.4 ETO05850.1 - 0.052 12.5 0.0 0.095 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2099) Hira PF07569.6 ETO05850.1 - 0.31 10.2 2.2 13 4.9 0.0 3.4 3 1 0 4 4 4 0 TUP1-like enhancer of split NAD_Gly3P_dh_N PF01210.18 ETO05850.1 - 0.43 10.3 2.8 16 5.1 0.2 3.7 4 2 1 5 5 5 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus WD40 PF00400.27 ETO05851.1 - 3e-20 71.2 4.9 1.6e-10 40.4 0.3 3.5 3 1 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO05851.1 - 0.011 13.9 0.3 0.037 12.1 0.1 1.7 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Sec23_trunk PF04811.10 ETO05851.1 - 0.1 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain PT-HINT PF07591.6 ETO05852.1 - 1.3e-08 34.8 1.1 9.3e-08 32.0 0.8 2.1 1 1 0 1 1 1 1 Pretoxin HINT domain AXH PF08517.7 ETO05852.1 - 0.0021 18.2 0.1 0.023 14.8 0.1 2.3 1 1 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) Hint_2 PF13403.1 ETO05852.1 - 0.083 12.8 0.0 8.7 6.2 0.0 2.3 2 0 0 2 2 2 0 Hint domain Hom_end_hint PF05203.11 ETO05852.1 - 0.084 12.6 0.2 0.16 11.7 0.2 1.5 1 0 0 1 1 1 0 Hom_end-associated Hint DUF1600 PF07667.6 ETO05852.1 - 0.23 11.5 4.7 0.59 10.2 3.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1600) WD40 PF00400.27 ETO05853.1 - 1.8e-70 230.4 11.1 1.3e-11 43.9 0.0 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO05853.1 - 2e-06 26.2 5.0 0.05 11.7 0.2 5.3 1 1 3 5 5 5 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO05853.1 - 0.00025 20.6 0.0 0.13 11.6 0.0 3.2 2 1 2 4 4 4 2 PQQ-like domain Cytochrom_D1 PF02239.11 ETO05853.1 - 0.0063 14.8 0.5 2 6.6 0.0 2.9 1 1 1 2 2 2 2 Cytochrome D1 heme domain PQQ PF01011.16 ETO05853.1 - 0.0077 15.7 1.5 1.4 8.5 0.0 4.4 5 0 0 5 5 5 1 PQQ enzyme repeat Kelch_6 PF13964.1 ETO05853.1 - 0.072 13.2 14.0 12 6.2 0.0 6.7 7 0 0 7 7 7 0 Kelch motif DUF1900 PF08954.6 ETO05853.1 - 0.084 12.3 3.1 6.9 6.1 0.0 4.4 3 1 2 5 5 5 0 Domain of unknown function (DUF1900) Kelch_5 PF13854.1 ETO05853.1 - 0.084 12.8 3.9 8.1 6.5 0.0 3.9 4 0 0 4 4 4 0 Kelch motif PD40 PF07676.7 ETO05853.1 - 0.1 12.2 4.6 13 5.6 0.0 4.7 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Kelch_2 PF07646.10 ETO05853.1 - 0.15 11.8 7.0 12 5.8 0.0 5.3 5 1 0 5 5 5 0 Kelch motif Proteasome_A_N PF10584.4 ETO05853.1 - 0.5 9.7 2.9 33 3.9 0.0 4.0 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 ETO05854.1 - 2.3e-53 176.2 21.0 3.8e-11 42.4 0.9 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO05854.1 - 7.1e-11 40.9 2.9 0.0011 17.1 0.3 4.9 2 1 2 4 4 4 3 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO05854.1 - 0.00014 22.1 2.9 0.00059 20.1 2.0 2.2 1 0 0 1 1 1 1 TRAF-type zinc finger DUF2344 PF10105.4 ETO05854.1 - 1.2 8.5 5.3 2.2 7.7 3.7 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) OmpH PF03938.9 ETO05854.1 - 8.4 6.3 12.7 14 5.5 8.8 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF730 PF05325.6 ETO05854.1 - 8.6 6.1 9.4 9.9 5.9 0.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF730) WD40 PF00400.27 ETO05855.1 - 6.2e-62 203.4 22.9 2e-10 40.0 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO05855.1 - 2.4e-08 32.6 4.9 0.093 10.8 0.0 4.9 2 2 2 4 4 4 4 Nucleoporin Nup120/160 WD40 PF00400.27 ETO05856.1 - 4.8e-138 444.7 42.7 4.7e-12 45.2 0.2 15.2 14 1 1 15 15 15 15 WD domain, G-beta repeat Nup160 PF11715.3 ETO05856.1 - 2e-13 49.3 25.6 0.39 8.7 0.0 12.0 4 2 8 12 12 12 8 Nucleoporin Nup120/160 Str_synth PF03088.11 ETO05856.1 - 3.4e-06 26.9 2.2 3.3 7.7 0.0 7.4 7 3 3 10 10 9 1 Strictosidine synthase Cytochrom_D1 PF02239.11 ETO05856.1 - 1.3e-05 23.6 7.3 2 6.6 0.0 5.5 1 1 2 5 5 5 4 Cytochrome D1 heme domain DUF1258 PF06869.7 ETO05856.1 - 0.00012 21.2 4.6 0.11 11.5 0.0 4.5 3 2 0 4 4 4 2 Protein of unknown function (DUF1258) PLD_C PF12357.3 ETO05856.1 - 0.0014 18.0 0.0 85 2.7 0.0 5.9 8 0 0 8 8 8 0 Phospholipase D C terminal PQQ_2 PF13360.1 ETO05856.1 - 0.0018 17.7 0.5 2.5 7.5 0.1 3.9 2 2 1 3 3 3 1 PQQ-like domain Peptidase_C69 PF03577.10 ETO05856.1 - 0.011 14.6 5.9 17 4.1 0.0 5.7 8 0 0 8 8 8 0 Peptidase family C69 Ribosomal_L28 PF00830.14 ETO05856.1 - 0.046 13.5 0.0 7.5 6.4 0.0 4.3 6 0 0 6 6 6 0 Ribosomal L28 family PD40 PF07676.7 ETO05856.1 - 0.17 11.5 29.8 4 7.2 0.1 10.8 13 0 0 13 13 13 0 WD40-like Beta Propeller Repeat USP7_C2 PF14533.1 ETO05856.1 - 1.8 7.9 4.6 89 2.4 0.0 5.3 5 3 1 6 6 6 0 Ubiquitin-specific protease C-terminal Ribosomal_L21p PF00829.16 ETO05856.1 - 4.3 7.5 7.7 58 3.9 0.1 5.6 6 2 1 7 7 7 0 Ribosomal prokaryotic L21 protein WD40 PF00400.27 ETO05857.1 - 4.2e-43 143.7 11.8 1e-09 37.8 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat PQQ_2 PF13360.1 ETO05857.1 - 4e-09 36.2 2.8 8.5e-05 22.1 0.0 3.3 2 1 0 3 3 3 3 PQQ-like domain Nup160 PF11715.3 ETO05857.1 - 3.7e-06 25.3 5.2 0.27 9.3 0.1 4.1 2 1 2 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO05857.1 - 1.8e-05 24.5 3.7 0.06 13.0 0.0 3.7 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO05857.1 - 3.2e-05 22.4 3.0 0.11 10.7 0.1 3.1 1 1 3 4 4 4 3 Cytochrome D1 heme domain PD40 PF07676.7 ETO05857.1 - 0.00091 18.8 7.8 1.1 8.9 0.1 5.0 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Ricin_B_lectin PF00652.17 ETO05857.1 - 0.019 14.9 0.7 0.28 11.2 0.1 2.6 2 1 1 3 3 3 0 Ricin-type beta-trefoil lectin domain DPPIV_N PF00930.16 ETO05857.1 - 0.022 13.3 0.2 0.69 8.4 0.0 2.8 2 2 2 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Hira PF07569.6 ETO05857.1 - 0.039 13.1 3.0 0.97 8.6 0.1 3.6 2 2 0 4 4 4 0 TUP1-like enhancer of split Proteasome_A_N PF10584.4 ETO05857.1 - 0.25 10.7 1.9 0.53 9.6 0.1 2.4 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature Flavokinase PF01687.12 ETO05858.1 - 0.015 15.1 0.9 0.68 9.8 0.0 2.2 2 0 0 2 2 2 0 Riboflavin kinase ACDC PF14733.1 ETO05858.1 - 0.2 11.8 4.2 0.62 10.2 2.9 2.1 1 1 0 1 1 1 0 AP2-coincident C-terminal Dexa_ind PF15198.1 ETO05860.1 - 0.018 14.9 0.3 0.031 14.1 0.2 1.3 1 0 0 1 1 1 0 Dexamethasone-induced CH PF00307.26 ETO05861.1 - 3.4e-37 126.7 1.5 2.9e-19 69.0 0.1 3.0 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 ETO05861.1 - 2.6e-05 23.7 0.0 0.00083 18.9 0.0 2.2 2 0 0 2 2 2 1 CAMSAP CH domain HATPase_c PF02518.21 ETO05862.1 - 0.00014 21.5 0.1 0.00017 21.2 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 ETO05862.1 - 0.00034 20.2 0.3 0.0004 20.0 0.2 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Saf-Nte_pilin PF09460.5 ETO05862.1 - 0.1 12.4 0.1 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Saf-pilin pilus formation protein WD40 PF00400.27 ETO05863.1 - 1e-17 63.2 2.7 9.6e-10 37.9 0.4 3.1 2 1 1 3 3 3 3 WD domain, G-beta repeat DUF4221 PF13970.1 ETO05863.1 - 0.0067 15.7 0.1 0.012 14.8 0.0 1.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4221) Nup160 PF11715.3 ETO05863.1 - 0.085 10.9 0.0 0.093 10.8 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DUF885 PF05960.6 ETO05864.1 - 0.13 11.3 12.4 0.14 11.2 8.4 1.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Peptidase_S7 PF00949.16 ETO05866.1 - 0.014 14.7 0.2 0.017 14.5 0.2 1.1 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Cadherin_pro PF08758.6 ETO05866.1 - 0.021 14.5 0.6 0.027 14.2 0.4 1.4 1 1 0 1 1 1 0 Cadherin prodomain like Ribosomal_L23 PF00276.15 ETO05868.1 - 1.9e-07 30.8 0.4 6e-07 29.3 0.3 1.8 1 0 0 1 1 1 1 Ribosomal protein L23 Nop25 PF09805.4 ETO05869.1 - 2.8e-11 43.6 4.6 2.8e-11 43.6 3.2 2.9 2 1 1 3 3 3 1 Nucleolar protein 12 (25kDa) Acetyltransf_11 PF13720.1 ETO05869.1 - 0.62 10.3 6.8 8.2 6.7 0.2 2.7 2 1 1 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 YscJ_FliF_C PF08345.6 ETO05869.1 - 2.6 8.0 11.8 2.6 8.0 7.1 1.9 1 1 0 1 1 1 0 Flagellar M-ring protein C-terminal ARGLU PF15346.1 ETO05869.1 - 3.9 7.2 28.3 0.75 9.5 4.7 2.3 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 ING PF12998.2 ETO05869.1 - 5.4 7.3 12.7 0.27 11.5 3.5 2.5 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding RVT_1 PF00078.22 ETO05870.1 - 3e-25 88.8 0.6 3e-25 88.8 0.4 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Aldo_ket_red PF00248.16 ETO05871.1 - 0.0055 15.5 0.5 0.0058 15.4 0.3 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4375 PF14300.1 ETO05871.1 - 0.027 14.4 1.3 0.05 13.5 0.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4375) HrcA_DNA-bdg PF03444.10 ETO05871.1 - 0.55 9.7 2.5 0.49 9.8 0.5 1.8 2 1 0 2 2 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Ribonuc_2-5A PF06479.7 ETO05871.1 - 0.76 9.6 5.6 1.7 8.5 3.9 1.8 1 1 0 1 1 1 0 Ribonuclease 2-5A GerA PF03323.8 ETO05871.1 - 1.1 7.3 4.1 1.2 7.1 2.8 1.1 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein Adaptin_binding PF10199.4 ETO05871.1 - 1.5 9.0 8.7 2.3 8.5 6.0 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 PY_rept_46 PF09689.5 ETO05871.1 - 8 6.8 9.8 0.72 10.2 1.1 2.6 2 1 0 2 2 2 0 Plasmodium yoelii repeat (PY_rept_46) MafB19-deam PF14437.1 ETO05872.1 - 0.05 13.2 0.6 0.056 13.0 0.4 1.1 1 0 0 1 1 1 0 MafB19-like deaminase WD40 PF00400.27 ETO05873.1 - 5.4e-06 26.0 0.2 3.9e-05 23.3 0.4 1.9 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF3637 PF12337.3 ETO05873.1 - 0.027 14.4 0.2 0.04 13.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3637) Nup160 PF11715.3 ETO05873.1 - 0.053 11.6 0.0 0.058 11.5 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 YrpD PF15493.1 ETO05874.1 - 0.021 14.4 0.4 0.028 14.0 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function, YrpD Bacteriocin_IIi PF11758.3 ETO05874.1 - 0.056 13.0 1.2 0.31 10.6 0.1 2.2 2 0 0 2 2 2 0 Aureocin-like type II bacteriocin MORN_2 PF07661.8 ETO05874.1 - 0.11 12.5 0.3 0.52 10.4 0.2 2.2 1 0 0 1 1 1 0 MORN repeat variant DUF2072 PF09845.4 ETO05875.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) DSPc PF00782.15 ETO05876.1 - 4.3e-12 45.7 0.2 6.8e-12 45.1 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 ETO05876.1 - 5.9e-07 28.7 0.8 7.1e-07 28.4 0.5 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase3 PF13350.1 ETO05876.1 - 0.0053 17.0 0.0 0.0077 16.4 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 ETO05876.1 - 0.014 14.7 0.3 0.031 13.6 0.2 1.6 1 1 0 1 1 1 0 Protein-tyrosine phosphatase UBACT PF02134.16 ETO05877.1 - 3.9e-24 83.9 0.8 9.5e-19 66.7 0.0 2.5 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 ETO05877.1 - 3.2e-09 36.0 0.1 7.4e-09 34.8 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UBA_e1_C PF09358.5 ETO05877.1 - 1.4e-05 25.2 0.7 1.4e-05 25.2 0.5 2.9 2 1 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain ThiF PF00899.16 ETO05878.1 - 5.8e-32 110.3 0.0 1e-31 109.5 0.0 1.4 1 0 0 1 1 1 1 ThiF family TF_Zn_Ribbon PF08271.7 ETO05880.1 - 0.00046 19.4 0.5 0.00046 19.4 0.3 2.1 2 0 0 2 2 2 1 TFIIB zinc-binding DUF2039 PF10217.4 ETO05880.1 - 0.012 15.6 1.4 0.033 14.2 1.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Lar_restr_allev PF14354.1 ETO05880.1 - 0.017 15.4 0.5 0.062 13.6 0.3 2.0 1 0 0 1 1 1 0 Restriction alleviation protein Lar DUF2616 PF11077.3 ETO05880.1 - 0.037 13.5 0.8 0.037 13.5 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2616) CDC45 PF02724.9 ETO05880.1 - 0.074 11.0 23.0 0.084 10.8 14.9 1.8 2 0 0 2 2 2 0 CDC45-like protein A2L_zn_ribbon PF08792.5 ETO05880.1 - 0.12 11.8 4.8 0.33 10.4 3.3 1.8 1 0 0 1 1 1 0 A2L zinc ribbon domain DZR PF12773.2 ETO05880.1 - 0.15 11.8 2.2 0.39 10.5 1.5 1.7 1 0 0 1 1 1 0 Double zinc ribbon Nucleoplasmin PF03066.10 ETO05880.1 - 0.26 10.8 11.1 0.51 9.8 7.7 1.6 1 0 0 1 1 1 0 Nucleoplasmin zf-Sec23_Sec24 PF04810.10 ETO05880.1 - 0.38 10.3 3.7 3.5 7.2 0.1 3.1 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Nop53 PF07767.6 ETO05880.1 - 0.91 8.4 18.9 0.079 11.9 9.9 1.5 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) NOA36 PF06524.7 ETO05880.1 - 1.2 8.2 18.5 1.1 8.4 10.1 2.3 2 0 0 2 2 2 0 NOA36 protein BUD22 PF09073.5 ETO05880.1 - 5.8 5.8 22.3 0.014 14.5 7.5 2.0 2 1 0 2 2 2 0 BUD22 DUF2542 PF10808.3 ETO05881.1 - 0.0012 19.1 0.0 0.002 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2542) MRP-S31 PF15433.1 ETO05881.1 - 0.044 13.1 10.8 0.057 12.8 7.5 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF2413 PF10310.4 ETO05881.1 - 0.88 8.3 13.4 1 8.0 9.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Vfa1 PF08432.5 ETO05881.1 - 0.94 9.4 16.9 1.3 8.9 11.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DOR PF14839.1 ETO05881.1 - 1.6 8.4 8.6 1.9 8.1 6.0 1.1 1 0 0 1 1 1 0 DOR family Paramyxo_ncap PF00973.14 ETO05881.1 - 3.7 6.1 9.3 4.9 5.7 6.4 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF4613 PF15390.1 ETO05883.1 - 0.83 7.7 6.0 0.83 7.7 4.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Pox_P4B PF03292.9 ETO05883.1 - 1.1 7.0 5.7 1.2 6.9 4.0 1.1 1 0 0 1 1 1 0 Poxvirus P4B major core protein NPR3 PF03666.8 ETO05883.1 - 1.4 7.3 10.6 1.6 7.1 7.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Tom37_C PF11801.3 ETO05883.1 - 1.7 8.4 6.2 2 8.2 4.3 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain DUF2413 PF10310.4 ETO05883.1 - 2 7.1 13.5 2.3 6.9 9.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF2201_N PF13203.1 ETO05883.1 - 5.6 6.0 8.8 6.4 5.8 6.1 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.9 ETO05883.1 - 6.8 4.5 14.4 7.6 4.4 10.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Sec62 PF03839.11 ETO05883.1 - 7.4 5.9 14.2 8.8 5.6 9.8 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF1510 PF07423.6 ETO05883.1 - 7.6 5.8 22.1 9.6 5.5 15.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF1510 PF07423.6 ETO05884.1 - 6.2e-06 25.7 1.4 6.2e-06 25.7 0.9 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) CDC45 PF02724.9 ETO05884.1 - 0.14 10.1 12.4 0.0035 15.4 4.2 1.5 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.7 ETO05884.1 - 0.57 8.0 21.4 0.92 7.3 14.8 1.2 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 ETO05884.1 - 0.67 8.6 31.4 1.4 7.5 21.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PPP4R2 PF09184.6 ETO05884.1 - 6.5 6.2 19.7 11 5.4 13.7 1.4 1 0 0 1 1 1 0 PPP4R2 Nucleoplasmin PF03066.10 ETO05884.1 - 7.6 6.0 21.1 18 4.7 14.6 1.6 1 0 0 1 1 1 0 Nucleoplasmin Sporozoite_P67 PF05642.6 ETO05884.1 - 8.4 4.1 9.6 13 3.5 6.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GrpE PF01025.14 ETO05885.1 - 6.8e-10 38.7 2.7 8.2e-10 38.4 1.8 1.0 1 0 0 1 1 1 1 GrpE DUF1517 PF07466.6 ETO05885.1 - 0.026 13.5 0.5 0.03 13.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DUF3782 PF12644.2 ETO05885.1 - 1.1 9.1 4.6 2 8.2 3.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) Y_phosphatase2 PF03162.8 ETO05887.1 - 2.6e-36 124.4 0.6 3.9e-36 123.9 0.4 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family FANCI_S1 PF14675.1 ETO05887.1 - 0.013 14.8 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 FANCI solenoid 1 DUF3439 PF11921.3 ETO05887.1 - 1.9 8.2 20.3 0.14 11.9 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) SR-25 PF10500.4 ETO05887.1 - 5.1 6.4 15.0 9 5.7 10.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein WD40 PF00400.27 ETO05889.1 - 0.073 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 WD domain, G-beta repeat Saw1 PF11561.3 ETO05889.1 - 0.12 11.7 4.0 0.19 11.0 2.8 1.4 1 1 0 1 1 1 0 Single strand annealing-weakened 1 DUF3276 PF11680.3 ETO05889.1 - 0.94 9.2 6.8 0.34 10.7 2.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3276) zf-C3HC4_2 PF13923.1 ETO05890.1 - 0.021 14.8 2.8 0.081 12.9 0.7 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO05890.1 - 0.12 12.2 4.7 0.12 12.2 1.3 2.4 2 1 1 3 3 3 0 Ring finger domain EBA-175_VI PF11556.3 ETO05890.1 - 1.2 9.3 6.3 2.3 8.3 4.4 1.5 1 1 0 1 1 1 0 Erythrocyte binding antigen 175 zf-RING-like PF08746.6 ETO05890.1 - 2.7 8.0 6.6 24 5.0 3.1 3.1 2 1 0 2 2 2 0 RING-like domain DUF3573 PF12097.3 ETO05891.1 - 0.019 13.5 1.5 0.02 13.5 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Viral_env_E26 PF11050.3 ETO05891.1 - 0.037 13.2 2.7 0.038 13.1 1.9 1.2 1 0 0 1 1 1 0 Virus envelope protein E26 Augurin PF15187.1 ETO05891.1 - 0.078 12.8 0.4 0.088 12.6 0.3 1.1 1 0 0 1 1 1 0 Oesophageal cancer-related gene 4 TSC22 PF01166.13 ETO05891.1 - 0.089 12.7 0.2 0.16 11.9 0.1 1.4 1 1 0 1 1 1 0 TSC-22/dip/bun family STAT_alpha PF01017.15 ETO05892.1 - 0.011 15.4 5.2 0.011 15.4 3.6 1.9 2 0 0 2 2 2 0 STAT protein, all-alpha domain DUF2205 PF10224.4 ETO05892.1 - 0.014 14.9 1.9 0.014 14.9 1.3 1.8 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF2312 PF10073.4 ETO05892.1 - 0.072 12.4 0.1 0.17 11.2 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) TSC22 PF01166.13 ETO05892.1 - 0.17 11.8 2.2 0.27 11.2 0.7 2.0 1 1 0 1 1 1 0 TSC-22/dip/bun family Cep57_MT_bd PF06657.8 ETO05892.1 - 0.19 11.6 5.1 9.3 6.2 0.7 3.2 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Atg14 PF10186.4 ETO05892.1 - 0.2 10.5 5.5 0.38 9.6 3.8 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_TATA_bd PF12325.3 ETO05892.1 - 0.21 11.3 10.1 2.2 8.0 4.4 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF972 PF06156.8 ETO05892.1 - 0.22 11.8 12.3 0.18 12.1 6.7 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Spc7 PF08317.6 ETO05892.1 - 0.49 9.0 9.1 0.12 10.9 4.0 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein KLRAQ PF10205.4 ETO05892.1 - 0.49 10.4 8.3 2.6 8.1 5.7 2.2 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein DUF904 PF06005.7 ETO05892.1 - 0.58 10.4 12.2 2.7 8.3 8.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF904) PhaP_Bmeg PF09602.5 ETO05892.1 - 1 9.1 8.2 0.18 11.6 3.1 1.5 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) IncA PF04156.9 ETO05892.1 - 1.5 8.3 7.1 2.8 7.4 4.9 1.5 1 0 0 1 1 1 0 IncA protein PspA_IM30 PF04012.7 ETO05892.1 - 2 7.6 11.2 0.4 10.0 5.4 1.5 2 0 0 2 2 2 0 PspA/IM30 family CENP-H PF05837.7 ETO05892.1 - 2.8 8.1 10.8 2 8.6 5.6 2.0 2 1 0 2 2 2 0 Centromere protein H (CENP-H) GrpE PF01025.14 ETO05892.1 - 7.5 6.0 11.3 21 4.6 4.8 2.5 2 1 0 2 2 2 0 GrpE WD40 PF00400.27 ETO05893.1 - 5.1e-66 216.3 12.9 9.3e-14 50.6 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO05893.1 - 4.3e-11 42.8 3.3 1.8e-07 31.0 0.3 2.8 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO05893.1 - 7.2e-10 37.6 5.5 0.0017 16.6 0.0 4.9 1 1 3 4 4 4 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO05893.1 - 1.3e-07 31.3 0.5 6.2e-05 22.5 0.1 2.2 2 0 0 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 ETO05893.1 - 9.9e-05 21.2 9.1 0.36 9.5 1.8 4.6 1 1 3 4 4 4 3 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO05893.1 - 0.0065 14.8 0.6 0.14 10.4 0.0 2.8 2 1 2 4 4 4 1 Cytochrome D1 heme domain DPPIV_N PF00930.16 ETO05893.1 - 0.015 13.9 0.1 3.7 6.0 0.0 3.0 1 1 2 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Rpn3_C PF08375.6 ETO05893.1 - 0.033 14.5 0.0 16 6.0 0.0 3.0 3 0 0 3 3 3 0 Proteasome regulatory subunit C-terminal Phage_int_SAM_5 PF13102.1 ETO05896.1 - 0.0077 16.2 0.2 0.014 15.4 0.1 1.5 1 0 0 1 1 1 1 Phage integrase SAM-like domain PBP1_TM PF14812.1 ETO05896.1 - 3.7 7.9 6.9 0.75 10.1 1.2 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WD40 PF00400.27 ETO05897.1 - 1.7e-73 240.0 13.7 9e-13 47.5 0.1 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO05897.1 - 1e-07 31.8 16.0 0.00035 20.5 0.2 7.3 7 1 0 7 7 7 1 Kelch motif Nup160 PF11715.3 ETO05897.1 - 7.9e-07 27.5 7.7 0.32 9.0 0.1 4.9 2 2 3 5 5 5 4 Nucleoporin Nup120/160 Kelch_4 PF13418.1 ETO05897.1 - 5.2e-06 26.1 2.9 0.00019 21.1 0.1 4.2 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO05897.1 - 6.8e-06 25.9 2.4 0.016 15.1 0.5 5.0 5 0 0 5 5 4 1 Kelch motif Cytochrom_D1 PF02239.11 ETO05897.1 - 8.2e-06 24.3 0.4 0.023 12.9 0.0 2.8 1 1 1 2 2 2 2 Cytochrome D1 heme domain Kelch_2 PF07646.10 ETO05897.1 - 1.4e-05 24.6 5.6 0.0091 15.7 0.1 5.3 6 0 0 6 6 6 1 Kelch motif PD40 PF07676.7 ETO05897.1 - 0.0014 18.2 9.9 0.26 10.9 0.0 5.3 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO05897.1 - 0.002 17.6 0.2 0.058 12.8 0.0 2.7 1 1 1 2 2 2 1 PQQ-like domain Kelch_1 PF01344.20 ETO05897.1 - 0.0041 16.6 6.1 0.04 13.4 0.5 4.2 4 0 0 4 4 4 1 Kelch motif Proteasome_A_N PF10584.4 ETO05897.1 - 0.026 13.8 4.4 6.5 6.1 0.0 4.4 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Kelch_3 PF13415.1 ETO05897.1 - 0.091 12.9 0.4 1.5 9.0 0.0 3.2 5 0 0 5 5 3 0 Galactose oxidase, central domain Resistin PF06954.6 ETO05897.1 - 0.11 12.8 0.0 56 4.1 0.0 3.6 3 1 0 3 3 3 0 Resistin WD40 PF00400.27 ETO05898.1 - 8e-31 104.8 19.6 1.6e-11 43.6 0.3 6.0 5 2 1 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO05898.1 - 2.7e-06 25.8 0.8 0.0049 15.0 0.2 2.8 1 1 1 2 2 2 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO05898.1 - 0.014 15.1 1.4 3.3 7.5 0.1 3.3 1 1 2 3 3 3 0 Ciliary BBSome complex subunit 2, middle region DUF851 PF05867.6 ETO05898.1 - 0.031 13.5 0.0 5.5 6.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF851) Transket_pyr PF02779.19 ETO05899.1 - 3.8e-29 101.4 0.0 5.4e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain HrcA PF01628.16 ETO05899.1 - 0.033 13.7 0.2 0.048 13.2 0.1 1.2 1 0 0 1 1 1 0 HrcA protein C terminal domain Rtt106 PF08512.7 ETO05900.1 - 0.00031 20.6 1.4 0.0008 19.3 0.1 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PH_10 PF15411.1 ETO05900.1 - 0.02 15.0 0.4 0.02 15.0 0.3 2.5 1 1 1 2 2 2 0 Pleckstrin homology domain DUF1053 PF06327.9 ETO05900.1 - 5.5 7.3 8.1 2.4 8.5 3.2 2.2 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1053) WD40 PF00400.27 ETO05902.1 - 0.0018 18.0 1.4 0.85 9.6 0.1 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat eIF2A PF08662.6 ETO05902.1 - 0.0059 16.3 0.5 0.02 14.6 0.1 1.8 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Vps16_N PF04841.8 ETO05902.1 - 0.024 13.1 0.5 0.029 12.9 0.4 1.1 1 0 0 1 1 1 0 Vps16, N-terminal region IKI3 PF04762.7 ETO05902.1 - 0.054 11.3 0.2 0.072 10.8 0.1 1.1 1 0 0 1 1 1 0 IKI3 family DUF682 PF05081.7 ETO05903.1 - 0.044 13.3 5.2 0.6 9.6 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF682) DsrD PF08679.6 ETO05903.1 - 2.9 7.9 10.8 0.24 11.4 1.6 2.3 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) Kelch_6 PF13964.1 ETO05904.1 - 4.2e-07 29.8 6.2 0.0024 17.9 0.3 3.4 2 2 1 3 3 3 3 Kelch motif Kelch_1 PF01344.20 ETO05904.1 - 9e-07 28.3 7.3 1e-06 28.1 0.7 2.9 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO05904.1 - 1.5e-06 27.7 2.0 0.0012 18.5 0.1 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 ETO05904.1 - 6.9e-05 22.8 0.1 0.0012 18.9 0.0 2.7 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO05904.1 - 0.00054 19.6 0.7 0.078 12.7 0.0 2.8 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO05904.1 - 0.0019 18.0 0.2 0.0019 18.0 0.1 3.6 4 1 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO05905.1 - 3.7e-08 33.0 4.3 0.00019 21.1 0.0 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO05905.1 - 2.8e-07 29.9 7.8 1.1e-05 24.8 0.3 4.6 5 0 0 5 5 5 1 Kelch motif Kelch_6 PF13964.1 ETO05905.1 - 0.00015 21.8 2.7 0.027 14.6 0.2 4.2 3 0 0 3 3 3 1 Kelch motif PTEN_C2 PF10409.4 ETO05905.1 - 0.0069 16.1 3.4 0.82 9.4 0.1 3.5 3 0 0 3 3 3 1 C2 domain of PTEN tumour-suppressor protein Kelch_2 PF07646.10 ETO05905.1 - 0.014 15.1 5.1 0.075 12.8 0.2 4.2 5 0 0 5 5 5 0 Kelch motif Kelch_3 PF13415.1 ETO05905.1 - 0.35 11.0 0.0 0.35 11.0 0.0 3.2 5 0 0 5 5 5 0 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO05905.1 - 0.56 10.2 11.9 1.2 9.1 0.6 4.5 5 0 0 5 5 5 0 Kelch motif DUF640 PF04852.7 ETO05905.1 - 4.9 7.3 6.6 1.6 8.9 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF640) AMP_N PF05195.11 ETO05906.1 - 2.2e-09 36.7 0.0 2.7e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain WD40 PF00400.27 ETO05907.1 - 2.8e-55 182.3 22.5 8e-11 41.3 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO05907.1 - 6.2e-08 31.2 9.8 0.0061 14.7 0.3 4.9 1 1 4 5 5 5 5 Nucleoporin Nup120/160 Rieske_2 PF13806.1 ETO05907.1 - 0.11 12.1 0.0 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Rieske-like [2Fe-2S] domain Kelch_6 PF13964.1 ETO05908.1 - 1.2e-08 34.7 4.3 0.0041 17.2 0.3 4.9 3 2 2 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO05908.1 - 1.9e-05 24.2 3.4 0.29 10.9 0.2 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO05908.1 - 2.8e-05 23.7 0.2 0.11 12.2 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO05908.1 - 0.004 16.6 4.4 19 4.8 0.0 4.5 4 1 0 4 4 4 2 Kelch motif CAP_GLY PF01302.20 ETO05911.1 - 1.2e-13 50.5 0.1 2e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain Pkinase PF00069.20 ETO05913.1 - 1.7e-10 40.4 0.4 1.3e-09 37.5 0.0 2.5 3 0 0 3 3 3 1 Protein kinase domain Mucin PF01456.12 ETO05913.1 - 0.00058 19.6 18.2 0.00058 19.6 12.6 2.5 2 0 0 2 2 2 1 Mucin-like glycoprotein Pkinase_Tyr PF07714.12 ETO05913.1 - 0.00067 18.8 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3439 PF11921.3 ETO05913.1 - 0.043 13.5 17.6 0.16 11.6 12.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TT_ORF1 PF02956.9 ETO05913.1 - 0.23 9.8 17.4 0.58 8.5 0.1 2.1 2 0 0 2 2 2 0 TT viral orf 1 TFIIA PF03153.8 ETO05913.1 - 0.33 10.8 21.2 0.098 12.5 7.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Phosphonate-bd PF12974.2 ETO05917.1 - 0.09 12.1 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein PA PF02225.17 ETO05917.1 - 0.13 11.9 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 PA domain SET PF00856.23 ETO05919.1 - 0.0044 17.3 0.4 0.0051 17.1 0.3 1.2 1 0 0 1 1 1 1 SET domain Macoilin PF09726.4 ETO05919.1 - 0.055 11.7 9.9 0.051 11.8 6.9 1.1 1 0 0 1 1 1 0 Transmembrane protein RP-C_C PF11800.3 ETO05919.1 - 0.087 12.5 4.2 0.14 11.8 2.9 1.5 1 0 0 1 1 1 0 Replication protein C C-terminal region MAP65_ASE1 PF03999.7 ETO05919.1 - 0.2 10.2 14.6 0.31 9.5 10.1 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF2201_N PF13203.1 ETO05919.1 - 0.36 9.9 7.7 0.41 9.7 5.4 1.2 1 1 0 1 1 1 0 Putative metallopeptidase domain Suf PF05843.9 ETO05919.1 - 0.47 10.1 9.3 0.61 9.7 6.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF789 PF05623.7 ETO05919.1 - 0.6 9.5 6.7 1.1 8.6 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF789) WD40 PF00400.27 ETO05920.1 - 4.2e-59 194.4 22.9 9.5e-14 50.6 0.2 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO05920.1 - 3.1e-06 25.6 3.6 0.016 13.3 0.1 4.3 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO05920.1 - 9.7e-05 20.8 0.7 0.03 12.6 0.0 3.2 1 1 2 3 3 3 2 Cytochrome D1 heme domain Kelch_4 PF13418.1 ETO05920.1 - 0.012 15.3 1.2 6.4 6.6 0.0 3.4 3 0 0 3 3 3 0 Galactose oxidase, central domain PD40 PF07676.7 ETO05920.1 - 0.073 12.7 8.8 5.8 6.6 0.1 4.7 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF334 PF03904.8 ETO05920.1 - 0.17 11.1 5.1 0.2 10.9 2.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF334) Kelch_6 PF13964.1 ETO05920.1 - 0.19 11.9 2.0 5.1 7.4 0.4 4.0 2 1 1 3 3 3 0 Kelch motif Kelch_1 PF01344.20 ETO05920.1 - 1.9 8.0 9.7 0.4 10.2 2.6 2.9 3 0 0 3 3 3 0 Kelch motif Imm47 PF15586.1 ETO05921.1 - 0.01 15.6 0.6 0.012 15.4 0.4 1.3 1 0 0 1 1 1 0 Immunity protein 47 Ribosomal_L35Ae PF01247.13 ETO05921.1 - 0.025 14.3 0.3 0.029 14.1 0.2 1.1 1 0 0 1 1 1 0 Ribosomal protein L35Ae RbcS PF12338.3 ETO05922.1 - 0.028 14.1 5.8 11 5.9 0.0 4.5 4 0 0 4 4 4 0 Ribulose-1,5-bisphosphate carboxylase small subunit LRR_6 PF13516.1 ETO05924.1 - 1e-09 37.4 21.1 0.18 11.9 0.1 8.4 9 0 0 9 9 9 4 Leucine Rich repeat RhoGAP PF00620.22 ETO05925.1 - 4e-17 62.2 0.5 1.4e-16 60.4 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain LRR_4 PF12799.2 ETO05925.1 - 0.051 13.2 1.0 0.22 11.1 0.3 2.2 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) DUF1800 PF08811.6 ETO05925.1 - 0.26 10.1 6.9 0.033 13.1 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1800) XPG_I_2 PF12813.2 ETO05926.1 - 0.0039 16.7 0.2 0.0082 15.6 0.1 1.5 1 0 0 1 1 1 1 XPG domain containing DUF2396 PF09654.5 ETO05926.1 - 0.041 13.8 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2396) DUF371 PF04027.8 ETO05926.1 - 0.044 13.4 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF371) CAP_GLY PF01302.20 ETO05928.1 - 6.5e-14 51.3 1.6 1.3e-13 50.4 1.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain MIP-T3 PF10243.4 ETO05928.1 - 0.00017 20.2 19.6 0.00017 20.2 13.6 4.1 1 1 3 4 4 4 1 Microtubule-binding protein MIP-T3 Ank_3 PF13606.1 ETO05929.1 - 8.4e-06 25.5 0.0 0.00014 21.7 0.0 3.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 ETO05929.1 - 1.3e-05 25.2 0.0 5.3e-05 23.3 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 ETO05929.1 - 3.8e-05 23.2 0.0 0.00022 20.8 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat HEAT_2 PF13646.1 ETO05929.1 - 0.00032 20.9 0.0 0.01 16.0 0.0 3.3 3 0 0 3 3 3 1 HEAT repeats Ank_2 PF12796.2 ETO05929.1 - 0.00073 19.8 0.4 0.012 15.9 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO05929.1 - 0.0069 16.8 0.5 0.063 13.8 0.1 3.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) HEAT PF02985.17 ETO05929.1 - 0.016 15.2 0.0 43 4.5 0.0 5.1 6 0 0 6 6 6 0 HEAT repeat FliG_M PF14841.1 ETO05929.1 - 0.038 13.9 0.2 16 5.5 0.0 3.2 2 0 0 2 2 2 0 FliG middle domain WD40 PF00400.27 ETO05930.1 - 9.1e-57 187.0 10.5 8.7e-11 41.2 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat PD40 PF07676.7 ETO05930.1 - 3.3e-08 32.9 0.9 1.1 9.0 0.0 5.7 6 0 0 6 6 6 3 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO05930.1 - 4.6e-08 32.8 0.0 1.2e-05 24.8 0.0 3.1 1 1 1 2 2 2 2 PQQ-like domain Nup160 PF11715.3 ETO05930.1 - 1.1e-07 30.4 3.7 0.031 12.4 0.0 4.3 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO05930.1 - 1.1e-05 23.8 2.2 0.025 12.9 0.3 3.3 1 1 2 4 4 4 4 Cytochrome D1 heme domain BBS2_Mid PF14783.1 ETO05930.1 - 0.00027 20.6 1.1 1.3 8.8 0.0 4.1 4 1 0 4 4 4 2 Ciliary BBSome complex subunit 2, middle region DPPIV_N PF00930.16 ETO05930.1 - 0.00067 18.3 0.1 0.0079 14.8 0.0 2.7 2 2 0 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nucleoporin_N PF08801.6 ETO05930.1 - 0.0046 15.7 12.8 1.9 7.1 0.1 4.3 1 1 1 4 4 4 3 Nup133 N terminal like PQQ PF01011.16 ETO05930.1 - 0.0082 15.6 0.0 1 9.0 0.1 3.7 4 0 0 4 4 4 1 PQQ enzyme repeat DUF1513 PF07433.6 ETO05930.1 - 0.062 12.1 0.0 1.7 7.4 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) Clathrin_propel PF01394.15 ETO05930.1 - 0.3 11.4 5.5 37 4.9 0.1 4.4 4 0 0 4 4 4 0 Clathrin propeller repeat Kelch_5 PF13854.1 ETO05931.1 - 9e-07 28.7 1.4 0.042 13.8 0.0 4.0 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO05931.1 - 4.3e-06 26.6 14.7 0.0055 16.8 0.6 4.9 5 1 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 ETO05931.1 - 3.6e-05 23.3 6.0 0.02 14.6 0.0 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO05931.1 - 9.2e-05 22.1 2.1 0.022 14.4 0.2 3.6 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO05931.1 - 0.0012 18.3 13.3 0.0083 15.6 0.5 4.6 4 1 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO05931.1 - 0.17 12.1 5.9 0.31 11.2 0.4 4.1 6 0 0 6 6 6 0 Galactose oxidase, central domain WD40 PF00400.27 ETO05932.1 - 7.6e-68 222.1 14.7 5.4e-12 45.1 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO05932.1 - 3.4e-12 46.5 0.6 7.4e-06 25.7 0.0 3.5 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO05932.1 - 5.1e-10 38.1 5.9 0.0088 14.2 0.0 4.4 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO05932.1 - 7.1e-10 37.7 0.3 7.1e-08 31.1 0.1 2.6 1 1 3 4 4 4 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO05932.1 - 4.3e-08 32.3 6.3 0.0013 17.5 0.6 5.2 1 1 3 4 4 4 2 Nup133 N terminal like PD40 PF07676.7 ETO05932.1 - 8.6e-06 25.2 5.0 10 5.9 0.0 6.8 7 1 0 7 7 7 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO05932.1 - 3.4e-05 23.4 0.1 0.00035 20.0 0.1 2.5 1 1 1 2 2 2 1 PQQ-like domain DPPIV_N PF00930.16 ETO05932.1 - 0.002 16.7 0.4 0.63 8.5 0.0 3.6 2 2 1 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region BBS2_Mid PF14783.1 ETO05932.1 - 0.01 15.5 1.7 9.5 6.0 0.0 4.3 4 2 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Resistin PF06954.6 ETO05932.1 - 0.043 14.0 0.4 7.8 6.8 0.1 3.2 2 2 2 4 4 4 0 Resistin Hira PF07569.6 ETO05932.1 - 0.063 12.4 0.5 15 4.7 0.0 3.9 2 1 3 5 5 5 0 TUP1-like enhancer of split DUF727 PF05303.7 ETO05932.1 - 0.074 12.8 0.8 14 5.5 0.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF727) Proteasome_A_N PF10584.4 ETO05932.1 - 0.49 9.7 8.1 6.9 6.0 0.0 4.7 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature Ras PF00071.17 ETO05934.1 - 2.2e-08 33.6 0.3 1e-05 24.9 0.1 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 ETO05934.1 - 5.6e-06 26.8 0.2 0.00051 20.5 0.1 2.3 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 ETO05934.1 - 9.5e-05 22.3 0.0 0.00018 21.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF3372 PF11852.3 ETO05934.1 - 0.27 10.3 2.0 0.37 9.9 0.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3372) HTH_44 PF14641.1 ETO05936.1 - 0.069 13.1 1.0 0.069 13.1 0.7 1.6 2 0 0 2 2 2 0 Helix-turn-helix DNA-binding domain of SPT6 MHC_II_alpha PF00993.15 ETO05936.1 - 0.073 12.6 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Class II histocompatibility antigen, alpha domain DUF1132 PF06575.7 ETO05936.1 - 0.82 9.9 3.9 0.98 9.7 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1132) WD40 PF00400.27 ETO05937.1 - 6.8e-40 133.5 2.1 2.4e-12 46.2 0.0 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat RelA_SpoT PF04607.12 ETO05937.1 - 3.7e-06 26.9 1.0 7.5e-06 25.9 0.7 1.5 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins PD40 PF07676.7 ETO05937.1 - 6.5e-05 22.4 0.4 26 4.6 0.0 4.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 ETO05937.1 - 0.0032 16.6 0.1 6 5.8 0.0 3.2 1 1 2 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 ETO05937.1 - 0.0041 15.3 0.2 0.29 9.2 0.0 2.5 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Mid2 PF04478.7 ETO05937.1 - 0.0056 16.1 3.7 0.26 10.6 0.1 2.8 2 1 1 3 3 3 2 Mid2 like cell wall stress sensor Nucleoporin_N PF08801.6 ETO05937.1 - 0.037 12.7 4.0 0.096 11.4 2.2 2.1 2 1 0 2 2 2 0 Nup133 N terminal like Proteasome_A_N PF10584.4 ETO05937.1 - 1.9 7.8 4.2 26 4.2 0.1 3.4 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature IncA PF04156.9 ETO05938.1 - 1.3e-05 24.8 3.9 1.3e-05 24.8 2.7 2.9 3 0 0 3 3 3 1 IncA protein Glyco_transf_20 PF00982.16 ETO05938.1 - 5.3e-05 21.8 1.4 5.7e-05 21.7 0.0 1.7 2 1 1 3 3 3 1 Glycosyltransferase family 20 DUF1843 PF08898.5 ETO05938.1 - 0.35 10.9 5.7 0.27 11.3 0.4 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1843) DUF3824 PF12868.2 ETO05938.1 - 0.46 11.4 0.1 0.46 11.4 0.1 2.7 2 1 1 3 3 3 0 Domain of unknwon function (DUF3824) DUF2407_C PF13373.1 ETO05938.1 - 0.67 9.8 4.6 1.1 9.1 0.0 2.7 2 1 0 2 2 2 0 DUF2407 C-terminal domain DUF4140 PF13600.1 ETO05938.1 - 0.73 10.3 6.1 5.2 7.5 3.1 2.8 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF912 PF06024.7 ETO05939.1 - 0.019 15.0 0.3 0.019 15.0 0.2 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PspB PF06667.7 ETO05939.1 - 1.2 9.1 4.0 2.4 8.1 0.0 2.7 3 0 0 3 3 3 0 Phage shock protein B Actin PF00022.14 ETO05940.1 - 0.0029 16.0 0.0 0.0033 15.9 0.0 1.1 1 0 0 1 1 1 1 Actin GTP_EFTU PF00009.22 ETO05940.1 - 0.0091 15.4 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Nse4_C PF08743.5 ETO05940.1 - 0.098 12.6 0.5 3.6 7.6 0.1 2.3 2 0 0 2 2 2 0 Nse4 C-terminal SPRY PF00622.23 ETO05941.1 - 2.5e-05 24.3 0.1 6.1e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 SPRY domain SAM_2 PF07647.12 ETO05941.1 - 0.025 14.4 0.1 0.3 10.9 0.1 2.7 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) DUF1014 PF06244.7 ETO05942.1 - 0.0022 18.1 1.6 0.0043 17.2 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1014) WD40 PF00400.27 ETO05943.1 - 1.7e-64 211.5 17.4 2.5e-10 39.8 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO05943.1 - 4.4e-09 35.0 1.2 0.17 9.9 0.0 5.0 1 1 1 4 4 4 4 Nucleoporin Nup120/160 Peptidase_C14 PF00656.17 ETO05944.1 - 2.6e-10 40.4 0.2 7.2e-10 38.9 0.1 1.8 1 0 0 1 1 1 1 Caspase domain Kelch_1 PF01344.20 ETO05944.1 - 0.00023 20.6 8.4 0.0046 16.4 0.2 4.8 5 0 0 5 5 5 1 Kelch motif Kelch_5 PF13854.1 ETO05944.1 - 0.00068 19.5 4.7 0.97 9.4 0.1 4.5 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 ETO05944.1 - 0.12 12.6 7.3 4.7 7.5 0.1 5.1 6 0 0 6 6 6 0 Kelch motif CAP_GLY PF01302.20 ETO05945.1 - 1.4e-223 723.0 108.0 6.5e-14 51.3 0.1 21.7 21 1 0 21 21 21 21 CAP-Gly domain CAP_GLY PF01302.20 ETO05946.1 - 1.2e-68 226.7 24.1 2.2e-19 68.9 0.3 6.5 6 0 0 6 6 6 6 CAP-Gly domain EF-hand_6 PF13405.1 ETO05946.1 - 3.9e-07 29.4 1.2 0.066 13.1 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 ETO05946.1 - 6.6e-05 22.4 0.9 0.11 12.1 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.1 ETO05946.1 - 0.00055 20.0 7.7 0.0017 18.4 2.9 3.1 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO05946.1 - 0.00071 18.7 11.0 0.011 15.0 0.0 3.8 5 0 0 5 5 5 2 EF hand DUF2088 PF09861.4 ETO05946.1 - 0.014 14.4 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2088) EF-hand_5 PF13202.1 ETO05946.1 - 0.017 14.4 7.7 0.12 11.7 0.1 3.0 3 0 0 3 3 3 0 EF hand DnaJ_CXXCXGXG PF00684.14 ETO05946.1 - 0.081 12.9 2.5 0.18 11.8 1.7 1.5 1 0 0 1 1 1 0 DnaJ central domain ODV-E18 PF10717.4 ETO05946.1 - 0.089 12.2 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 OAD_gamma PF04277.8 ETO05946.1 - 0.17 12.3 2.6 1.4 9.3 0.0 2.8 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain zf-NADH-PPase PF09297.6 ETO05946.1 - 0.48 9.9 6.2 32 4.1 0.1 3.6 2 1 1 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Baculo_11_kDa PF06143.6 ETO05946.1 - 1.9 7.8 4.6 1.7 8.0 1.1 2.4 3 0 0 3 3 3 0 Baculovirus 11 kDa family MS_channel PF00924.13 ETO05946.1 - 7.8 5.7 7.6 4.5 6.5 0.0 3.1 3 0 0 3 3 2 0 Mechanosensitive ion channel DUF2146 PF10220.4 ETO05947.1 - 0.0047 15.0 7.7 0.0058 14.6 5.3 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2146) RRM_1 PF00076.17 ETO05947.1 - 0.016 14.8 0.1 0.016 14.8 0.1 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Suf PF05843.9 ETO05947.1 - 0.073 12.7 6.6 0.088 12.5 4.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RRM_6 PF14259.1 ETO05947.1 - 0.082 12.8 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Menin PF05053.8 ETO05947.1 - 0.57 8.2 4.2 0.66 8.0 2.9 1.1 1 0 0 1 1 1 0 Menin FAM60A PF15396.1 ETO05947.1 - 3.7 7.2 17.2 5.2 6.7 11.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Dsh_C PF12316.3 ETO05947.1 - 4.5 7.3 5.8 5.9 6.9 4.0 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal SOBP PF15279.1 ETO05947.1 - 5.7 7.2 8.3 6.6 7.0 5.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2149 PF09919.4 ETO05949.1 - 0.0045 17.0 0.6 0.013 15.5 0.2 1.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2149) PDR_CDR PF06422.7 ETO05950.1 - 0.014 15.0 0.1 6 6.5 0.0 2.6 2 0 0 2 2 2 0 CDR ABC transporter RRM_1 PF00076.17 ETO05952.1 - 0.00018 21.1 0.2 0.00042 19.8 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_jaz PF12171.3 ETO05952.1 - 0.00021 21.3 0.4 0.00021 21.3 0.3 4.6 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding RRM_6 PF14259.1 ETO05952.1 - 0.00092 19.1 0.1 0.0022 17.9 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO05952.1 - 0.037 13.8 0.2 0.07 12.9 0.1 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Herpes_UL45 PF05473.7 ETO05953.1 - 0.044 13.1 0.1 0.083 12.3 0.0 1.5 1 0 0 1 1 1 0 UL45 protein DUF4448 PF14610.1 ETO05953.1 - 0.25 10.8 5.6 0.54 9.7 3.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) Hid1 PF12722.2 ETO05953.1 - 0.38 8.3 12.7 0.47 8.0 8.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3590 PF12148.3 ETO05954.1 - 0.013 15.1 0.0 0.052 13.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3590) CHU_C PF13585.1 ETO05954.1 - 0.045 13.6 1.8 0.056 13.3 0.5 1.6 2 0 0 2 2 2 0 C-terminal domain of CHU protein family Stap_Strp_tox_C PF02876.12 ETO05954.1 - 0.046 13.8 0.5 0.062 13.4 0.3 1.3 1 0 0 1 1 1 0 Staphylococcal/Streptococcal toxin, beta-grasp domain Kinesin PF00225.18 ETO05955.1 - 1.5e-12 46.9 5.6 1.3e-11 43.7 0.0 2.0 1 1 1 2 2 2 2 Kinesin motor domain DUF290 PF01060.18 ETO05955.1 - 1.5 8.8 6.2 1.9 8.5 0.8 2.4 1 1 1 2 2 2 0 Transthyretin-like family DUF1041 PF06292.12 ETO05956.1 - 0.084 13.0 4.8 0.31 11.2 1.1 2.3 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1041) PulS_OutS PF09691.5 ETO05957.1 - 0.059 13.3 5.2 0.12 12.4 3.2 1.8 1 1 1 2 2 2 0 Bacterial chaperone lipoprotein (PulS_OutS) Inh PF02974.9 ETO05957.1 - 0.92 9.1 3.6 1.4 8.5 0.3 2.1 1 1 1 2 2 2 0 Protease inhibitor Inh CDC45 PF02724.9 ETO05958.1 - 0.071 11.1 7.2 0.12 10.3 5.0 1.3 1 0 0 1 1 1 0 CDC45-like protein RGS PF00615.14 ETO05960.1 - 9.4e-25 87.0 4.2 1.8e-24 86.0 2.9 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain cNMP_binding PF00027.24 ETO05960.1 - 0.017 14.9 0.0 0.053 13.3 0.0 1.9 1 1 0 1 1 1 0 Cyclic nucleotide-binding domain adh_short PF00106.20 ETO05961.1 - 5.8e-22 78.3 0.0 5.4e-14 52.4 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 ETO05961.1 - 6.1e-06 26.0 0.0 1.8e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 ETO05961.1 - 9.1e-06 25.6 0.0 0.078 12.7 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 ETO05961.1 - 0.00073 19.5 0.0 0.0019 18.2 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 ETO05961.1 - 0.0019 17.7 0.0 0.0086 15.5 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 ETO05961.1 - 0.023 13.9 0.0 0.052 12.7 0.0 1.6 1 0 0 1 1 1 0 NmrA-like family HSBP1 PF06825.7 ETO05961.1 - 0.32 10.5 1.5 2.1 7.9 1.0 2.2 1 1 0 1 1 1 0 Heat shock factor binding protein 1 Peptidase_S9_N PF02897.10 ETO05962.1 - 6.5e-101 337.9 2.1 7.9e-101 337.6 1.4 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain ATG2_CAD PF13329.1 ETO05962.1 - 0.044 13.3 0.0 0.089 12.3 0.0 1.4 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif Peptidase_S9 PF00326.16 ETO05963.1 - 6.7e-61 205.2 0.0 7.6e-61 205.0 0.0 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 ETO05963.1 - 0.089 12.2 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Beta-lactamase PF00144.19 ETO05964.1 - 2.3e-21 76.1 0.2 5.4e-12 45.3 0.0 2.9 2 1 0 2 2 2 2 Beta-lactamase Biopterin_H PF00351.16 ETO05966.1 - 2.2e-124 414.5 0.1 3e-124 414.0 0.1 1.2 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase WD40 PF00400.27 ETO05967.1 - 4.5e-59 194.3 15.3 2.3e-10 39.9 0.4 7.5 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO05967.1 - 7.7e-13 47.4 7.9 0.00085 17.5 0.1 5.4 2 2 4 6 6 6 5 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO05967.1 - 0.0081 15.9 6.6 5.9 6.7 0.1 5.4 1 1 4 5 5 5 3 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.27 ETO05968.1 - 1.3e-49 164.4 27.1 4.4e-10 39.0 0.1 7.2 6 1 1 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO05968.1 - 2.8e-07 29.0 6.3 0.39 8.7 0.0 5.1 2 2 2 5 5 5 5 Nucleoporin Nup120/160 zf-RING_2 PF13639.1 ETO05968.1 - 0.0041 16.9 3.6 0.0041 16.9 2.5 2.6 2 0 0 2 2 2 1 Ring finger domain Alg6_Alg8 PF03155.10 ETO05969.1 - 1.9e-51 175.3 23.4 1.1e-44 153.0 6.7 2.0 1 1 1 2 2 2 2 ALG6, ALG8 glycosyltransferase family DUF4131 PF13567.1 ETO05969.1 - 0.0011 18.3 0.6 0.0011 18.3 0.4 4.0 2 1 1 4 4 4 1 Domain of unknown function (DUF4131) DUF2798 PF11391.3 ETO05969.1 - 0.095 12.4 0.2 0.095 12.4 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2798) PsbN PF02468.10 ETO05969.1 - 0.18 11.4 2.5 2.8 7.6 0.2 2.7 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) DUF4268 PF14088.1 ETO05970.1 - 0.0046 16.6 1.2 0.0047 16.6 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4268) ORC6 PF05460.8 ETO05972.1 - 0.093 11.8 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Serinc PF03348.10 ETO05973.1 - 0.43 9.2 1.8 0.49 9.0 1.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Zip PF02535.17 ETO05973.1 - 0.51 9.3 4.8 0.65 8.9 3.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2839 PF10999.3 ETO05974.1 - 0.0024 17.8 0.0 0.0058 16.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2839) CLU_N PF15044.1 ETO05974.1 - 0.087 12.9 0.1 1.2 9.3 0.0 2.5 2 1 1 3 3 3 0 Mitochondrial function, CLU-N-term IR1-M PF12185.3 ETO05975.1 - 0.049 13.3 1.2 0.1 12.3 0.8 1.5 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain DUF3184 PF11380.3 ETO05975.1 - 1.1 7.0 2.8 1.6 6.5 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3184) DUF3671 PF12420.3 ETO05976.1 - 0.005 16.7 0.3 0.0089 15.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function KdpA PF03814.10 ETO05976.1 - 0.063 11.2 0.8 0.1 10.5 0.2 1.5 1 1 1 2 2 2 0 Potassium-transporting ATPase A subunit B56 PF01603.15 ETO05978.1 - 8.2e-44 149.8 0.2 1e-43 149.5 0.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) PMSR PF01625.16 ETO05979.1 - 0.044 13.6 0.1 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 Peptide methionine sulfoxide reductase ABC_tran PF00005.22 ETO05980.1 - 6.3e-05 23.2 0.0 0.00019 21.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_5 PF07728.9 ETO05980.1 - 0.00011 21.8 0.0 0.00028 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF258 PF03193.11 ETO05980.1 - 0.00014 21.1 0.0 0.00023 20.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA PF00004.24 ETO05980.1 - 0.0012 19.0 0.2 0.0035 17.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 ETO05980.1 - 0.0012 18.9 0.1 0.0092 16.0 0.0 2.3 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.1 ETO05980.1 - 0.0014 18.6 0.1 0.0044 17.0 0.0 1.9 2 1 1 3 3 3 1 AAA ATPase domain UPF0079 PF02367.12 ETO05980.1 - 0.0015 18.1 0.2 0.0048 16.5 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 ETO05980.1 - 0.0036 16.7 0.1 0.0061 16.0 0.0 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation T2SE PF00437.15 ETO05980.1 - 0.0062 15.4 0.0 0.0093 14.8 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 ETO05980.1 - 0.0069 16.5 0.0 0.019 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 ETO05980.1 - 0.0097 14.8 0.0 0.021 13.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 ETO05980.1 - 0.011 15.2 0.1 0.059 12.8 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain Miro PF08477.8 ETO05980.1 - 0.013 16.0 0.0 0.037 14.5 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein MCM PF00493.18 ETO05980.1 - 0.021 13.6 0.0 0.042 12.6 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family IstB_IS21 PF01695.12 ETO05980.1 - 0.022 14.1 0.0 0.13 11.7 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_23 PF13476.1 ETO05980.1 - 0.023 15.0 3.1 0.19 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 ETO05980.1 - 0.029 14.0 0.0 0.072 12.7 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 ETO05980.1 - 0.051 13.2 2.0 0.11 12.0 0.0 2.4 2 1 1 3 3 3 0 NACHT domain Bac_DnaA PF00308.13 ETO05980.1 - 0.074 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_24 PF13479.1 ETO05980.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 ETO05980.1 - 1.1 9.5 3.1 1.9 8.7 0.1 2.4 2 1 0 2 2 2 0 AAA domain LMBR1 PF04791.11 ETO05983.1 - 0.39 9.2 7.8 0.57 8.6 5.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Daxx PF03344.10 ETO05983.1 - 2.5 6.4 38.0 0.17 10.3 15.5 2.1 2 0 0 2 2 2 0 Daxx Family PMSI1 PF15322.1 ETO05983.1 - 3.2 6.7 15.1 6.2 5.8 10.4 1.4 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative DUF1318 PF07027.7 ETO05985.1 - 0.00091 19.4 0.1 0.0029 17.7 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1318) HhH-GPD PF00730.20 ETO05985.1 - 0.0013 18.9 0.1 1.3 9.3 0.0 3.8 4 0 0 4 4 4 1 HhH-GPD superfamily base excision DNA repair protein DUF4366 PF14283.1 ETO05985.1 - 0.0027 17.1 1.8 0.0027 17.1 1.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4366) PglZ PF08665.7 ETO05985.1 - 0.11 12.1 9.5 0.029 14.0 2.4 2.8 2 1 1 3 3 3 0 PglZ domain CPSase_L_D3 PF02787.14 ETO05985.1 - 0.11 12.2 2.3 1.8 8.3 0.2 2.9 3 0 0 3 3 3 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_Mga PF08280.6 ETO05986.1 - 0.015 15.0 1.1 0.36 10.6 0.6 2.4 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain RVT_1 PF00078.22 ETO05987.1 - 1.8e-21 76.4 0.0 3.6e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ubiquitin PF00240.18 ETO05989.1 - 0.00052 19.3 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family EF-hand_6 PF13405.1 ETO05989.1 - 0.023 14.5 0.6 0.15 11.9 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.27 ETO05989.1 - 0.027 13.7 0.0 0.11 11.8 0.0 2.1 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.1 ETO05989.1 - 0.027 14.5 0.2 0.094 12.8 0.1 2.0 1 0 0 1 1 1 0 EF-hand domain pair Rad60-SLD PF11976.3 ETO05989.1 - 0.049 13.3 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like CAP_GLY PF01302.20 ETO05990.1 - 1.1e-07 31.4 0.0 1.6e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Pkinase_Tyr PF07714.12 ETO05991.1 - 8.1e-11 41.4 1.6 1.1e-10 41.0 0.1 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 ETO05991.1 - 2.4e-10 40.0 0.1 2.4e-10 40.0 0.0 2.3 3 0 0 3 3 3 1 Protein kinase domain HEAT PF02985.17 ETO05992.1 - 1.9e-07 30.5 4.3 0.024 14.6 0.0 4.1 4 0 0 4 4 4 3 HEAT repeat Pkinase_Tyr PF07714.12 ETO05993.1 - 5.2e-26 91.2 0.0 6.6e-26 90.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 ETO05993.1 - 7.8e-21 74.3 0.0 1e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SAM_2 PF07647.12 ETO05995.1 - 0.0004 20.1 0.1 0.00077 19.2 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4200 PF13863.1 ETO05995.1 - 0.00069 19.5 14.1 0.0012 18.7 9.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) SAM_1 PF00536.25 ETO05995.1 - 0.0018 18.4 0.1 0.011 15.8 0.1 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Carboxyl_trans PF01039.17 ETO05995.1 - 0.023 13.0 0.0 0.034 12.5 0.0 1.2 1 0 0 1 1 1 0 Carboxyl transferase domain DUF1682 PF07946.9 ETO05995.1 - 0.032 13.0 12.0 0.063 12.1 8.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) RFC1 PF08519.7 ETO05996.1 - 4.2e-37 127.2 0.0 9e-37 126.2 0.0 1.5 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain VID27 PF08553.5 ETO05996.1 - 0.034 12.4 4.0 0.044 12.0 2.8 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein CDC45 PF02724.9 ETO05996.1 - 0.77 7.7 7.6 1.1 7.2 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.7 ETO05996.1 - 4.7 7.0 9.4 7.1 6.4 6.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA PF00004.24 ETO05997.1 - 3.3e-11 43.4 0.2 2.6e-10 40.5 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETO05997.1 - 5.2e-05 23.3 0.0 0.00045 20.3 0.0 2.3 1 1 1 2 2 2 1 AAA domain BRCT PF00533.21 ETO05997.1 - 7.9e-05 22.7 0.8 0.006 16.7 0.1 3.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain RuvB_N PF05496.7 ETO05997.1 - 0.00017 20.7 0.0 0.00039 19.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 ETO05997.1 - 0.00066 19.3 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 ETO05997.1 - 0.00079 20.2 0.5 0.0034 18.1 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 ETO05997.1 - 0.018 15.0 0.0 0.055 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.1 ETO05997.1 - 0.027 14.0 0.0 0.07 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain FPN1 PF06963.7 ETO05997.1 - 3.1 6.0 4.2 1.5 7.1 0.9 1.8 2 0 0 2 2 2 0 Ferroportin1 (FPN1) SR-25 PF10500.4 ETO05998.1 - 0.023 14.1 16.4 0.055 12.9 11.4 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Nbl1_Borealin_N PF10444.4 ETO05998.1 - 2.1 7.7 4.9 7.4 6.0 0.0 3.6 5 0 0 5 5 5 0 Nbl1 / Borealin N terminal Mus7 PF09462.5 ETO05999.1 - 0.0048 15.8 0.3 0.0059 15.5 0.2 1.1 1 0 0 1 1 1 1 Mus7/MMS22 family TACC PF05010.9 ETO05999.1 - 0.13 12.0 1.9 0.18 11.5 1.3 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) SNARE PF05739.14 ETO05999.1 - 0.13 11.9 4.0 0.1 12.3 0.5 2.0 1 1 1 2 2 2 0 SNARE domain Cauli_DNA-bind PF03310.8 ETO05999.1 - 0.41 10.5 2.7 0.62 9.9 1.9 1.3 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein Spt20 PF12090.3 ETO06000.1 - 0.0033 16.7 0.5 0.012 14.9 0.3 1.8 1 1 1 2 2 2 1 Spt20 family CitX PF03802.9 ETO06000.1 - 0.035 13.5 2.1 0.39 10.1 0.0 2.2 2 0 0 2 2 2 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase DUF530 PF04409.7 ETO06001.1 - 0.041 11.9 0.1 0.043 11.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF530) Kelch_6 PF13964.1 ETO06003.1 - 1.1e-09 38.0 1.6 0.0062 16.6 0.0 4.7 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO06003.1 - 4.5e-05 22.9 4.3 0.14 11.6 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO06003.1 - 0.00019 21.1 0.3 1.7 8.5 0.0 3.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO06003.1 - 0.00034 20.6 0.4 0.53 10.5 0.0 3.9 4 0 0 4 4 4 1 Galactose oxidase, central domain N_Asn_amidohyd PF14736.1 ETO06003.1 - 0.03 13.1 0.6 2.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein N-terminal asparagine amidohydrolase Kelch_5 PF13854.1 ETO06003.1 - 0.17 11.8 4.3 14 5.8 0.0 4.5 6 0 0 6 6 6 0 Kelch motif WD40 PF00400.27 ETO06004.1 - 2.6e-77 252.1 12.7 1.6e-12 46.8 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO06004.1 - 6.7e-12 45.5 0.5 7.1e-05 22.5 0.1 3.3 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO06004.1 - 1.9e-10 39.5 5.7 0.014 13.6 0.1 5.0 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO06004.1 - 7.4e-07 28.2 5.1 0.23 10.1 0.1 5.0 1 1 3 4 4 4 3 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO06004.1 - 1.2e-05 23.8 0.6 0.41 8.8 0.0 3.1 1 1 2 3 3 3 3 Cytochrome D1 heme domain Resistin PF06954.6 ETO06004.1 - 2.7e-05 24.3 0.2 13 6.1 0.0 4.4 1 1 3 5 5 5 0 Resistin PQQ_2 PF13360.1 ETO06004.1 - 4.4e-05 23.0 0.0 0.0014 18.1 0.0 2.6 1 1 2 3 3 3 2 PQQ-like domain Proteasome_A_N PF10584.4 ETO06004.1 - 0.0011 18.2 1.2 9.9 5.5 0.0 4.6 5 0 0 5 5 5 1 Proteasome subunit A N-terminal signature PD40 PF07676.7 ETO06004.1 - 0.0015 18.1 6.2 2.4 7.9 0.1 5.4 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 ETO06004.1 - 0.0045 16.1 3.2 6.2 5.8 0.0 3.8 1 1 4 5 5 5 2 Protein of unknown function (DUF1258) PQQ PF01011.16 ETO06004.1 - 0.015 14.7 0.0 6.3 6.5 0.0 4.0 4 0 0 4 4 4 0 PQQ enzyme repeat DUF4083 PF13314.1 ETO06004.1 - 0.026 14.3 0.3 0.062 13.1 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) MCM PF00493.18 ETO06006.1 - 1.3e-70 237.8 2.2 2.9e-37 128.2 0.4 2.4 2 0 0 2 2 2 2 MCM2/3/5 family Mg_chelatase PF01078.16 ETO06006.1 - 4.7e-05 22.6 0.0 0.0011 18.1 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 ETO06006.1 - 0.0034 16.9 0.0 0.0073 15.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 ETO06006.1 - 0.013 15.8 2.4 0.084 13.2 0.9 2.6 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF3396 PF11876.3 ETO06006.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3396) Phage_int_SAM_2 PF12834.2 ETO06006.1 - 4 7.8 6.6 4.4 7.7 0.5 2.8 3 0 0 3 3 3 0 Phage integrase, N-terminal FAIM1 PF06905.8 ETO06008.1 - 0.0065 15.6 0.4 0.024 13.7 0.0 1.8 1 1 0 2 2 2 1 Fas apoptotic inhibitory molecule (FAIM1) Pro_dh PF01619.13 ETO06009.1 - 0.0073 15.3 1.5 0.015 14.3 1.0 1.4 1 0 0 1 1 1 1 Proline dehydrogenase DUF755 PF05501.6 ETO06009.1 - 0.094 12.7 6.2 0.76 9.8 4.1 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF755) DUF3808 PF10300.4 ETO06010.1 - 0.096 11.2 0.1 0.11 11.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) VIT1 PF01988.14 ETO06012.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 VIT family DDHD PF02862.12 ETO06013.1 - 0.0047 16.7 4.2 0.0055 16.5 2.9 1.1 1 0 0 1 1 1 1 DDHD domain Ribosomal_60s PF00428.14 ETO06013.1 - 0.011 16.1 3.3 0.021 15.1 2.3 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein NARP1 PF12569.3 ETO06013.1 - 0.015 14.1 3.9 0.017 13.9 2.7 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RP-C_C PF11800.3 ETO06013.1 - 0.033 13.8 4.0 0.037 13.7 2.8 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF3402 PF11882.3 ETO06013.1 - 0.035 13.1 3.4 0.043 12.8 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) PIG-S PF10510.4 ETO06013.1 - 0.065 11.8 2.0 0.076 11.6 1.4 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein DUF913 PF06025.7 ETO06013.1 - 0.085 11.5 2.4 0.11 11.1 1.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TRAP_alpha PF03896.11 ETO06013.1 - 0.15 11.0 2.5 0.18 10.7 1.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FANCI_S4 PF14678.1 ETO06013.1 - 0.15 11.1 2.8 0.17 10.9 1.4 1.5 1 1 0 1 1 1 0 FANCI solenoid 4 Ycf1 PF05758.7 ETO06013.1 - 0.16 9.6 5.3 0.19 9.4 3.7 1.1 1 0 0 1 1 1 0 Ycf1 Spore_coat_CotO PF14153.1 ETO06013.1 - 0.19 11.1 10.8 0.21 10.9 7.5 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF45 PF01863.12 ETO06013.1 - 0.27 11.0 5.4 0.33 10.7 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF45 DUF1510 PF07423.6 ETO06013.1 - 0.27 10.5 11.5 0.31 10.3 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RXT2_N PF08595.6 ETO06013.1 - 0.29 10.9 8.0 0.43 10.3 5.5 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.1 ETO06013.1 - 0.37 10.4 3.6 0.59 9.8 2.5 1.3 1 0 0 1 1 1 0 FAM176 family BTV_NS2 PF04514.7 ETO06013.1 - 0.73 8.6 8.8 0.86 8.4 6.1 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF809 PF05663.6 ETO06013.1 - 0.83 9.5 6.0 1.3 8.9 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF809) DUF3987 PF13148.1 ETO06013.1 - 0.86 8.0 6.3 1.1 7.7 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Sec62 PF03839.11 ETO06013.1 - 0.97 8.8 5.0 1.2 8.5 3.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4551 PF15087.1 ETO06013.1 - 1.2 7.4 5.9 1.5 7.1 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PBP_sp32 PF07222.7 ETO06013.1 - 1.3 8.1 12.4 1.6 7.8 8.6 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 VID27 PF08553.5 ETO06013.1 - 1.5 6.9 9.7 1.7 6.7 6.7 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Vfa1 PF08432.5 ETO06013.1 - 1.7 8.6 12.4 2.2 8.2 8.6 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NPR3 PF03666.8 ETO06013.1 - 1.9 6.8 8.6 2.6 6.4 5.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Bac_export_2 PF01312.14 ETO06013.1 - 3 6.6 4.8 4.4 6.0 3.3 1.2 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family DUF4446 PF14584.1 ETO06015.1 - 1.1 9.1 6.5 0.35 10.6 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) PhageMin_Tail PF10145.4 ETO06015.1 - 8.6 5.9 7.0 19 4.8 4.8 1.6 1 1 0 1 1 1 0 Phage-related minor tail protein CAP_GLY PF01302.20 ETO06016.1 - 6.1e-09 35.4 0.1 0.12 12.1 0.0 3.5 3 0 0 3 3 3 3 CAP-Gly domain AAA_22 PF13401.1 ETO06020.1 - 0.008 16.3 0.1 0.035 14.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain WD40 PF00400.27 ETO06021.1 - 4.3e-79 257.8 17.4 1.3e-11 43.8 0.0 7.0 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO06021.1 - 1.3e-11 44.6 0.7 2.5e-05 24.0 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A DUF1258 PF06869.7 ETO06021.1 - 3.8e-05 22.9 1.7 1.8 7.5 0.0 3.9 2 1 2 4 4 4 3 Protein of unknown function (DUF1258) Proteasome_A_N PF10584.4 ETO06021.1 - 0.00058 19.1 2.5 3.4 7.0 0.0 4.5 4 0 0 4 4 4 1 Proteasome subunit A N-terminal signature PD40 PF07676.7 ETO06021.1 - 0.00091 18.8 2.1 16 5.3 0.0 4.7 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Mid2 PF04478.7 ETO06021.1 - 0.0033 16.8 0.6 0.17 11.3 0.0 3.4 2 1 2 4 4 4 1 Mid2 like cell wall stress sensor HARP PF07443.8 ETO06021.1 - 0.0095 15.2 0.2 4.9 6.6 0.0 3.9 3 1 1 4 4 4 1 HepA-related protein (HARP) Me-amine-dh_H PF06433.6 ETO06021.1 - 0.053 12.1 0.0 0.14 10.7 0.0 1.6 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) Resistin PF06954.6 ETO06021.1 - 0.29 11.4 2.6 28 5.0 0.1 3.8 2 2 3 5 5 5 0 Resistin Septum_form PF13845.1 ETO06022.1 - 0.068 12.6 0.1 0.071 12.6 0.1 1.1 1 0 0 1 1 1 0 Septum formation zf-BED PF02892.10 ETO06022.1 - 0.25 11.1 2.9 1.1 9.0 0.1 2.5 2 0 0 2 2 2 0 BED zinc finger zf-like PF04071.7 ETO06022.1 - 0.3 10.7 5.9 0.061 13.0 0.8 2.0 1 1 1 2 2 2 0 Cysteine-rich small domain eIF3_N PF09440.5 ETO06022.1 - 1.1 9.4 5.0 1.6 8.8 3.5 1.3 1 1 0 1 1 1 0 eIF3 subunit 6 N terminal domain Pox_Ag35 PF03286.9 ETO06022.1 - 1.6 8.2 11.7 1.8 8.0 8.1 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Eapp_C PF10238.4 ETO06022.1 - 3.3 7.6 10.7 6.6 6.6 0.3 2.2 1 1 1 2 2 2 0 E2F-associated phosphoprotein DUF4451 PF14616.1 ETO06022.1 - 5.9 6.6 10.3 1.1 8.9 1.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) TMPIT PF07851.8 ETO06022.1 - 6 5.8 6.4 6 5.8 4.4 1.0 1 0 0 1 1 1 0 TMPIT-like protein SRA1 PF07304.6 ETO06024.1 - 0.03 14.0 0.2 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 Steroid receptor RNA activator (SRA1) Peptidase_C14 PF00656.17 ETO06025.1 - 0.0059 16.3 0.8 0.011 15.4 0.3 1.6 2 0 0 2 2 2 1 Caspase domain Pkinase PF00069.20 ETO06026.1 - 3e-21 75.7 0.2 8.6e-13 48.0 0.1 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO06026.1 - 5.7e-09 35.4 0.1 3e-07 29.8 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 ETO06026.1 - 5.4e-05 22.3 0.1 9.1e-05 21.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO06026.1 - 0.1 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family YfbU PF03887.9 ETO06028.1 - 0.085 12.4 0.3 0.11 12.0 0.2 1.3 1 1 0 1 1 1 0 YfbU domain Ribosomal_L22e PF01776.12 ETO06028.1 - 0.086 12.8 0.6 0.11 12.4 0.3 1.3 1 1 0 1 1 1 0 Ribosomal L22e protein family PHB_acc_N PF07879.6 ETO06028.1 - 0.12 12.1 0.1 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 PHB/PHA accumulation regulator DNA-binding domain Ank_2 PF12796.2 ETO06029.1 - 7.1e-30 103.2 3.0 1.4e-16 60.5 0.9 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETO06029.1 - 3.8e-24 83.2 1.3 1.4e-08 34.0 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 ETO06029.1 - 5.1e-21 72.6 0.6 8.6e-07 28.6 0.1 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 ETO06029.1 - 5.2e-20 71.0 2.2 5.6e-07 29.6 0.2 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO06029.1 - 2.4e-19 69.3 1.3 4.8e-13 49.2 0.2 3.3 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Rad51 PF08423.6 ETO06030.1 - 5.6e-08 32.0 0.0 1e-07 31.1 0.0 1.4 2 0 0 2 2 2 1 Rad51 KaiC PF06745.8 ETO06030.1 - 1.8e-05 23.9 0.3 8.6e-05 21.7 0.0 2.2 1 1 1 2 2 2 1 KaiC AAA_25 PF13481.1 ETO06030.1 - 0.00091 18.6 0.1 0.0083 15.5 0.0 2.3 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 ETO06030.1 - 0.0043 16.9 0.2 0.03 14.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain Pox_Rap94 PF03294.9 ETO06030.1 - 0.027 12.4 0.9 0.03 12.3 0.6 1.1 1 0 0 1 1 1 0 RNA polymerase-associated transcription specificity factor, Rap94 AAA_22 PF13401.1 ETO06030.1 - 0.068 13.3 0.2 0.3 11.2 0.0 2.1 2 1 0 2 2 2 0 AAA domain RecA PF00154.16 ETO06030.1 - 0.078 12.0 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein FtsK_SpoIIIE PF01580.13 ETO06030.1 - 0.081 12.3 0.1 0.15 11.5 0.0 1.5 1 1 0 1 1 1 0 FtsK/SpoIIIE family Lectin_N PF03954.9 ETO06030.1 - 0.089 12.1 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain zf-CCCH PF00642.19 ETO06031.1 - 8e-08 31.7 4.3 1.3e-07 31.0 3.0 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Tmemb_cc2 PF10267.4 ETO06031.1 - 0.024 13.2 1.3 0.036 12.6 0.9 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Osmo_CC PF08946.5 ETO06031.1 - 0.034 14.1 3.4 0.034 14.1 2.4 2.0 2 0 0 2 2 2 0 Osmosensory transporter coiled coil AAA_32 PF13654.1 ETO06031.1 - 0.086 11.4 0.4 0.13 10.9 0.2 1.2 1 0 0 1 1 1 0 AAA domain Pex16 PF08610.5 ETO06032.1 - 8.1e-16 57.9 0.0 1.3e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) SAPS PF04499.10 ETO06032.1 - 9.3e-05 21.2 1.0 0.00012 20.9 0.7 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein SMN PF06003.7 ETO06032.1 - 0.01 15.0 0.3 0.014 14.4 0.2 1.2 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) CDC45 PF02724.9 ETO06032.1 - 0.016 13.2 2.7 0.02 12.9 1.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF912 PF06024.7 ETO06032.1 - 0.56 10.2 6.4 0.076 13.0 0.8 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) GCIP PF13324.1 ETO06032.1 - 0.63 9.2 3.8 0.91 8.6 2.6 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF2457 PF10446.4 ETO06032.1 - 8.7 4.9 15.1 12 4.5 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CRISPR_Cas2 PF09827.4 ETO06033.1 - 0.13 12.4 0.1 1.4 9.1 0.0 2.3 2 0 0 2 2 2 0 CRISPR associated protein Cas2 SAGA-Tad1 PF12767.2 ETO06034.1 - 7.2e-05 22.5 20.4 7.2e-05 22.5 14.2 2.5 3 0 0 3 3 3 1 Transcriptional regulator of RNA polII, SAGA, subunit SprA-related PF12118.3 ETO06034.1 - 0.00013 21.3 52.4 0.017 14.4 3.8 2.1 2 0 0 2 2 2 2 SprA-related family DUF4452 PF14618.1 ETO06035.1 - 0.046 13.5 6.6 0.063 13.0 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) WD40 PF00400.27 ETO06036.1 - 2.7e-45 150.6 21.7 9.1e-10 38.0 0.2 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO06036.1 - 3.1e-06 25.6 0.5 0.0079 14.3 0.0 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO06036.1 - 0.0051 16.5 0.0 1.4 8.6 0.0 3.1 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A End3 PF12761.2 ETO06036.1 - 0.043 13.4 4.0 0.086 12.4 2.8 1.4 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 HAUS-augmin3 PF14932.1 ETO06036.1 - 0.044 12.9 5.6 0.079 12.1 3.9 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Borrelia_REV PF03978.8 ETO06036.1 - 0.044 13.5 3.4 0.08 12.6 2.4 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein Allexi_40kDa PF05549.6 ETO06036.1 - 0.054 12.7 1.5 0.084 12.1 1.1 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF3601 PF12208.3 ETO06036.1 - 0.056 13.3 0.0 1.1 9.2 0.0 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF3601) AAA_13 PF13166.1 ETO06036.1 - 0.095 11.1 5.4 0.13 10.7 3.8 1.1 1 0 0 1 1 1 0 AAA domain DUF1995 PF09353.5 ETO06036.1 - 0.12 12.0 0.1 0.19 11.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1995) Flexi_CP PF00286.15 ETO06036.1 - 0.12 12.1 1.0 0.19 11.4 0.1 1.8 2 0 0 2 2 2 0 Viral coat protein Cob_adeno_trans PF01923.13 ETO06036.1 - 0.12 12.1 1.9 0.19 11.4 1.3 1.3 1 0 0 1 1 1 0 Cobalamin adenosyltransferase BING4CT PF08149.6 ETO06036.1 - 0.14 11.6 1.0 2.8 7.4 0.0 3.3 3 1 1 4 4 4 0 BING4CT (NUC141) domain ACCA PF03255.9 ETO06036.1 - 0.34 10.4 2.1 0.7 9.4 1.4 1.6 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit MRP-S26 PF14943.1 ETO06036.1 - 0.47 10.0 6.9 0.69 9.4 4.8 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 V_ATPase_I PF01496.14 ETO06036.1 - 0.69 7.7 3.9 0.86 7.3 2.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TcdA_TcdB_pore PF12920.2 ETO06036.1 - 0.75 7.6 5.2 0.96 7.2 3.6 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain Topoisom_I PF01028.15 ETO06036.1 - 0.77 8.8 5.4 1.1 8.2 3.7 1.3 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, catalytic core Fib_alpha PF08702.5 ETO06036.1 - 1.3 9.1 7.9 2.6 8.1 5.5 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF3373 PF11853.3 ETO06036.1 - 1.4 7.3 4.3 1.1 7.6 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) DUF4407 PF14362.1 ETO06036.1 - 1.5 7.6 3.8 2.2 7.1 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) XhlA PF10779.4 ETO06036.1 - 4.4 7.2 6.5 8.3 6.4 4.5 1.4 1 0 0 1 1 1 0 Haemolysin XhlA FemAB PF02388.11 ETO06036.1 - 5.1 5.6 9.1 7.4 5.1 6.3 1.1 1 0 0 1 1 1 0 FemAB family TPR_12 PF13424.1 ETO06037.1 - 1.5e-61 204.2 14.1 2e-18 66.0 1.3 5.8 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETO06037.1 - 3.9e-31 106.4 15.4 2.1e-09 36.8 1.4 5.4 5 0 0 5 5 5 4 TPR repeat TPR_1 PF00515.23 ETO06037.1 - 1.1e-26 91.3 32.8 6.6e-06 25.5 0.8 9.1 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.12 ETO06037.1 - 5.6e-25 85.1 28.0 5.6e-05 22.7 0.0 9.6 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_7 PF13176.1 ETO06037.1 - 5.3e-23 78.9 14.7 0.0036 16.9 0.0 8.6 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_10 PF13374.1 ETO06037.1 - 1.3e-19 69.4 0.0 0.0034 17.2 0.0 7.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO06037.1 - 2.1e-19 67.7 40.9 9.6e-05 21.8 0.1 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_17 PF13431.1 ETO06037.1 - 1.6e-12 46.5 1.7 0.54 10.5 0.0 8.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO06037.1 - 7.4e-12 45.6 1.3 0.13 12.9 0.0 5.5 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO06037.1 - 1.4e-10 41.3 0.6 0.35 11.2 0.0 5.3 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO06037.1 - 1.1e-09 38.0 0.2 9.8 7.1 0.0 6.9 8 1 1 9 9 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO06037.1 - 3e-07 30.4 14.8 0.00077 19.7 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO06037.1 - 0.00076 19.5 18.0 0.59 10.3 0.0 5.4 1 1 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.4 ETO06037.1 - 0.0078 16.1 1.8 0.042 13.7 0.0 3.1 4 1 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO06037.1 - 0.013 15.4 10.6 0.3 11.0 0.0 4.7 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 ETO06037.1 - 0.59 10.0 20.1 24 4.8 1.1 6.3 3 2 3 6 6 6 0 MIT (microtubule interacting and transport) domain WD40 PF00400.27 ETO06038.1 - 1.3e-174 560.6 45.7 1.5e-11 43.7 0.0 16.2 16 0 0 16 16 16 16 WD domain, G-beta repeat Pentapeptide PF00805.17 ETO06038.1 - 2.2e-06 26.7 0.4 4.7e-06 25.7 0.2 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Cytochrom_D1 PF02239.11 ETO06038.1 - 3.6e-06 25.5 11.6 0.77 7.9 0.1 5.8 4 1 1 6 6 6 5 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO06038.1 - 6.7e-06 25.1 39.0 0.35 9.5 0.7 9.8 1 1 6 9 9 9 5 Nup133 N terminal like DUF1258 PF06869.7 ETO06038.1 - 7.3e-06 25.2 11.7 1.4 7.8 0.0 7.2 4 3 2 8 8 8 3 Protein of unknown function (DUF1258) Pentapeptide_4 PF13599.1 ETO06038.1 - 1.9e-05 24.3 0.2 5.4e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) F420_ligase PF01996.11 ETO06038.1 - 4.3e-05 22.7 0.0 0.14 11.2 0.0 4.0 4 0 0 4 4 4 1 F420-0:Gamma-glutamyl ligase PD40 PF07676.7 ETO06038.1 - 4.6e-05 22.9 20.8 9.9 5.9 0.0 9.7 11 0 0 11 11 11 1 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO06038.1 - 0.0046 17.1 4.1 9.9 6.5 0.0 6.5 3 2 4 7 7 7 1 Resistin Pentapeptide_3 PF13576.1 ETO06038.1 - 0.0047 16.7 0.9 0.02 14.7 0.6 2.1 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Gmad1 PF10647.4 ETO06038.1 - 0.0056 16.1 0.0 1.2 8.5 0.0 3.8 3 1 0 3 3 3 1 Lipoprotein LpqB beta-propeller domain WD40 PF00400.27 ETO06039.1 - 8.1e-13 47.7 0.9 6.6e-10 38.4 0.0 2.4 2 1 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO06039.1 - 0.041 12.0 0.0 0.046 11.8 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 zf-RING_2 PF13639.1 ETO06041.1 - 9.2e-07 28.5 3.1 9.2e-07 28.5 2.2 2.9 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO06041.1 - 5.6e-06 26.2 3.3 5.6e-06 26.2 2.3 3.0 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO06041.1 - 3.3e-05 23.5 11.2 3.5e-05 23.4 2.0 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 ETO06041.1 - 4.1e-05 23.1 3.2 4.1e-05 23.1 2.2 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO06041.1 - 4.1e-05 23.1 15.6 0.00015 21.3 1.9 2.6 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETO06041.1 - 0.0088 16.1 1.4 0.0088 16.1 1.0 3.1 2 2 1 3 3 3 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 ETO06041.1 - 0.03 14.0 3.8 0.03 14.0 2.6 3.1 2 1 1 3 3 3 0 RING-type zinc-finger VWA_2 PF13519.1 ETO06042.1 - 0.01 15.9 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain VWA PF00092.23 ETO06042.1 - 0.017 14.8 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain Anoctamin PF04547.7 ETO06043.1 - 0.0032 16.2 3.3 0.0037 15.9 2.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF2723 PF11028.3 ETO06043.1 - 0.0091 15.5 0.9 0.013 15.0 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2723) YqhR PF11085.3 ETO06043.1 - 0.049 13.1 2.4 0.094 12.2 1.7 1.4 1 0 0 1 1 1 0 Conserved membrane protein YqhR AdoHcyase PF05221.12 ETO06046.1 - 5.7e-103 343.5 0.5 7.9e-103 343.0 0.4 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 ETO06046.1 - 5.7e-33 114.0 6.8 8e-19 68.0 1.1 2.4 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase, NAD binding domain BALF1 PF06861.6 ETO06046.1 - 0.037 13.4 0.0 0.085 12.2 0.0 1.5 1 0 0 1 1 1 0 BALF1 protein WD40 PF00400.27 ETO06047.1 - 3.1e-24 83.9 7.7 1.5e-10 40.4 0.7 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO06047.1 - 1.5e-06 26.6 1.6 0.00032 18.9 0.3 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO06047.1 - 0.038 13.7 0.1 0.058 13.1 0.1 1.3 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.27 ETO06048.1 - 1.6e-11 43.6 0.1 4.9e-05 23.0 0.1 2.7 2 1 0 2 2 2 2 WD domain, G-beta repeat PUB PF09409.5 ETO06050.1 - 0.004 16.8 3.5 0.004 16.8 2.4 3.7 2 1 0 2 2 2 1 PUB domain Integrin_B_tail PF07965.7 ETO06050.1 - 0.058 13.8 0.2 0.28 11.6 0.0 2.2 2 0 0 2 2 2 0 Integrin beta tail domain KGK PF08872.5 ETO06050.1 - 1 9.5 8.3 15 5.7 0.4 3.6 3 1 0 3 3 3 0 KGK domain YqgF PF14639.1 ETO06052.1 - 0.045 13.3 0.2 0.078 12.5 0.1 1.4 1 1 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 Mucin2_WxxW PF13330.1 ETO06052.1 - 0.25 11.8 3.7 1.2 9.6 0.1 2.2 2 0 0 2 2 2 0 Mucin-2 protein WxxW repeating region Kinesin PF00225.18 ETO06053.1 - 0.0018 17.0 0.3 0.0056 15.4 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain DUF4582 PF15189.1 ETO06053.1 - 0.04 13.1 0.4 0.055 12.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4582) WD40 PF00400.27 ETO06054.1 - 5.7e-53 175.0 21.1 3.2e-11 42.6 0.1 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO06054.1 - 7.2e-13 47.5 4.4 4.5e-06 25.0 0.1 4.9 1 1 4 5 5 5 5 Nucleoporin Nup120/160 Ras PF00071.17 ETO06055.1 - 0.027 13.8 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 Ras family SH3_1 PF00018.23 ETO06056.1 - 1.4e-05 24.3 0.0 0.24 10.8 0.0 4.1 4 0 0 4 4 4 2 SH3 domain SH3_2 PF07653.12 ETO06056.1 - 4.5e-05 22.8 0.8 0.035 13.5 0.3 3.8 3 1 0 3 3 3 1 Variant SH3 domain SH3_9 PF14604.1 ETO06056.1 - 0.025 14.1 0.0 1.2 8.8 0.0 3.3 4 0 0 4 4 4 0 Variant SH3 domain Mec-17 PF05301.6 ETO06057.1 - 1.3e-34 118.7 0.2 5.3e-34 116.7 0.0 2.0 1 1 1 2 2 2 1 Touch receptor neuron protein Mec-17 14-3-3 PF00244.15 ETO06058.1 - 4.2e-46 156.9 5.1 2.2e-29 102.2 0.1 2.1 1 1 1 2 2 2 2 14-3-3 protein TPR_8 PF13181.1 ETO06058.1 - 4 7.4 6.6 8.2 6.4 0.2 3.3 2 1 2 4 4 4 0 Tetratricopeptide repeat Ras PF00071.17 ETO06059.1 - 7.6e-12 44.9 0.7 4.3e-08 32.7 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 ETO06059.1 - 6.1e-06 26.7 0.1 1.7e-05 25.3 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 ETO06059.1 - 0.0073 15.4 0.4 0.009 15.1 0.3 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 ETO06059.1 - 0.02 14.1 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO06059.1 - 0.077 12.4 0.7 0.16 11.4 0.5 1.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain YajC PF02699.10 ETO06059.1 - 0.12 12.0 1.5 13 5.4 0.6 2.4 2 0 0 2 2 2 0 Preprotein translocase subunit SecA_DEAD PF07517.9 ETO06061.1 - 0.00014 21.2 0.0 0.00016 21.0 0.0 1.1 1 0 0 1 1 1 1 SecA DEAD-like domain FTR1 PF03239.9 ETO06061.1 - 0.012 14.5 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 0 Iron permease FTR1 family Kelch_1 PF01344.20 ETO06062.1 - 1.7e-07 30.6 6.4 0.061 12.8 0.1 4.0 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.1 ETO06062.1 - 2.2e-06 27.4 0.4 2.5 8.1 0.0 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 ETO06062.1 - 5.3e-06 26.3 0.2 1.9 8.7 0.0 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 ETO06062.1 - 0.00083 19.0 0.6 7.3 6.5 0.1 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO06062.1 - 0.0087 15.8 1.1 2.8 7.7 0.0 3.5 2 1 1 3 3 3 2 Galactose oxidase, central domain TLD PF07534.11 ETO06062.1 - 0.026 14.5 4.2 0.04 13.9 0.2 2.8 1 1 1 3 3 3 0 TLD WD40 PF00400.27 ETO06063.1 - 1.5e-24 84.8 2.8 2.6e-11 42.9 0.2 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat ENTH PF01417.15 ETO06064.1 - 0.12 12.2 3.6 0.35 10.7 0.3 2.0 2 0 0 2 2 2 0 ENTH domain FrhB_FdhB_C PF04432.8 ETO06064.1 - 0.12 11.7 0.2 0.14 11.5 0.1 1.1 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus zf-TRAF PF02176.13 ETO06065.1 - 1.7e-05 25.0 2.1 8.8e-05 22.8 1.5 2.3 1 0 0 1 1 1 1 TRAF-type zinc finger zf-H2C2_5 PF13909.1 ETO06065.1 - 0.019 15.1 2.0 1.3 9.4 1.4 3.4 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Kelch_6 PF13964.1 ETO06065.1 - 0.028 14.5 2.5 0.17 12.1 0.1 2.9 3 0 0 3 3 3 0 Kelch motif Med9 PF07544.8 ETO06065.1 - 0.38 10.5 7.1 0.086 12.5 1.2 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 zf-RING_2 PF13639.1 ETO06065.1 - 0.72 9.7 5.0 0.55 10.1 1.0 2.7 2 0 0 2 2 2 0 Ring finger domain WD40 PF00400.27 ETO06066.1 - 1.3e-37 126.3 10.2 6.7e-11 41.6 0.4 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO06066.1 - 0.0043 15.8 7.8 0.21 10.2 1.4 3.4 2 2 1 3 3 3 2 Nup133 N terminal like PD40 PF07676.7 ETO06066.1 - 0.011 15.3 0.7 3.5 7.3 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Hce2 PF14856.1 ETO06066.1 - 0.13 12.1 1.6 0.43 10.5 0.1 2.2 2 0 0 2 2 2 0 Pathogen effector; putative necrosis-inducing factor PT PF04886.7 ETO06067.1 - 6.7e-62 204.4 203.5 2.9e-08 32.8 5.8 13.9 2 2 5 7 7 7 5 PT repeat Radical_SAM PF04055.16 ETO06070.1 - 3.4e-09 37.0 0.0 4.2e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Radical SAM superfamily THDPS_N PF14790.1 ETO06070.1 - 0.011 15.2 0.0 0.014 15.0 0.0 1.1 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Kelch_5 PF13854.1 ETO06072.1 - 0.00014 21.7 0.0 0.0024 17.7 0.0 2.7 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.20 ETO06072.1 - 0.0008 18.9 0.1 0.014 14.9 0.0 2.7 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETO06072.1 - 0.0023 18.0 0.0 0.37 11.0 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETO06072.1 - 0.028 14.2 0.1 0.12 12.1 0.0 2.2 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO06072.1 - 0.092 12.5 0.0 1.3 8.8 0.0 2.8 3 0 0 3 3 3 0 Kelch motif DUF3753 PF12575.3 ETO06074.1 - 0.058 13.2 3.3 0.14 11.9 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) ETRAMP PF09716.5 ETO06074.1 - 0.09 12.7 0.3 0.09 12.7 0.2 1.8 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) O-ag_pol_Wzy PF14296.1 ETO06074.1 - 0.22 10.0 1.1 0.36 9.3 0.7 1.2 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy CorA PF01544.13 ETO06074.1 - 2.1 7.3 8.1 3.6 6.5 5.6 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Chlam_PMP PF02415.12 ETO06075.1 - 0.45 10.8 0.1 0.45 10.8 0.1 7.5 8 0 0 8 8 8 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Glug PF07581.7 ETO06075.1 - 9.6 6.6 13.5 0.97 9.7 0.3 4.9 5 1 0 5 5 5 0 The GLUG motif Pneumovirus_M2 PF06436.6 ETO06076.1 - 0.039 13.1 3.0 0.036 13.2 0.9 2.0 1 1 0 1 1 1 0 Pneumovirus matrix protein 2 (M2) DUF4028 PF13220.1 ETO06076.1 - 0.52 10.0 4.3 0.2 11.2 0.7 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4028) RTC PF01137.16 ETO06078.1 - 1.5e-19 69.6 0.0 1.8e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 ETO06078.1 - 8.5e-11 41.7 0.7 9.3e-10 38.4 0.5 2.1 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain PX PF00787.19 ETO06079.1 - 3.5e-13 49.3 3.0 7.4e-13 48.2 2.1 1.6 1 0 0 1 1 1 1 PX domain RGCC PF15151.1 ETO06080.1 - 0.024 15.0 0.1 0.053 13.9 0.1 1.6 1 0 0 1 1 1 0 Response gene to complement 32 protein family Baculo_PEP_C PF04513.7 ETO06080.1 - 0.21 11.4 3.9 1.5 8.6 0.4 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.6 ETO06080.1 - 0.39 10.6 6.8 0.79 9.6 0.5 3.2 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF45 PF01863.12 ETO06080.1 - 0.85 9.3 10.5 0.038 13.7 2.1 2.0 1 1 0 2 2 2 0 Protein of unknown function DUF45 DUF740 PF05340.7 ETO06082.1 - 0.013 13.8 0.3 0.016 13.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) DUF3655 PF12379.3 ETO06082.1 - 1.1 9.2 7.6 0.65 9.9 2.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3655) TPR_12 PF13424.1 ETO06084.1 - 4.1e-73 241.3 8.1 3.7e-25 87.6 0.1 4.1 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETO06084.1 - 2.3e-35 120.0 25.3 5.7e-13 48.3 0.4 3.4 1 1 3 4 4 4 4 TPR repeat TPR_10 PF13374.1 ETO06084.1 - 7.6e-33 111.4 0.0 9.8e-09 34.8 0.0 6.1 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.23 ETO06084.1 - 1.1e-25 88.1 22.6 2e-07 30.3 1.1 5.2 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO06084.1 - 1.9e-24 83.4 2.7 5.5e-06 25.7 0.2 4.8 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO06084.1 - 1.2e-23 81.0 14.1 4.2e-05 23.1 0.3 5.2 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.1 ETO06084.1 - 2.8e-21 73.6 29.2 2.1e-05 23.9 0.5 5.2 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETO06084.1 - 6.3e-13 47.8 5.0 0.014 15.5 0.0 5.1 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO06084.1 - 5e-11 42.9 0.0 5.4e-05 23.7 0.0 3.5 1 1 3 4 4 4 3 Tetratricopeptide repeat SNAP PF14938.1 ETO06084.1 - 1.5e-09 37.4 0.9 3.4e-06 26.4 0.2 2.1 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_14 PF13428.1 ETO06084.1 - 1.9e-09 37.3 0.0 0.044 14.4 0.0 4.5 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO06084.1 - 1.6e-08 34.4 2.1 2.2 8.9 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO06084.1 - 8.5e-07 29.0 17.7 6.1e-05 23.0 1.6 2.9 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO06084.1 - 1.5e-06 28.4 0.5 0.0055 17.0 0.0 3.9 1 1 4 5 5 5 2 Tetratricopeptide repeat TPR_3 PF07720.7 ETO06084.1 - 6.8e-06 25.7 8.5 0.31 10.8 0.3 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat PPR PF01535.15 ETO06084.1 - 8.2e-05 22.3 9.3 0.6 10.2 0.2 4.8 4 1 1 5 5 5 2 PPR repeat RPN7 PF10602.4 ETO06084.1 - 0.00044 19.6 6.4 2.2 7.6 0.0 4.1 2 1 2 4 4 4 1 26S proteasome subunit RPN7 SHNi-TPR PF10516.4 ETO06084.1 - 0.00092 18.4 1.3 32 3.8 0.0 5.5 5 2 1 6 6 6 0 SHNi-TPR Ten1_2 PF15490.1 ETO06084.1 - 0.0021 17.6 0.0 9 5.9 0.0 3.5 2 1 2 4 4 4 0 Telomere-capping, CST complex subunit TPR_21 PF09976.4 ETO06084.1 - 0.0052 16.7 1.6 0.12 12.3 0.1 3.3 3 1 1 4 4 4 1 Tetratricopeptide repeat MIT PF04212.13 ETO06084.1 - 0.0068 16.2 15.3 2.8 7.8 0.6 4.6 4 1 0 4 4 4 2 MIT (microtubule interacting and transport) domain Sel1 PF08238.7 ETO06084.1 - 0.0097 16.5 3.1 13 6.6 0.0 4.1 4 0 0 4 4 4 0 Sel1 repeat TPR_9 PF13371.1 ETO06084.1 - 0.018 14.9 0.0 0.12 12.2 0.0 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF2670 PF10875.3 ETO06084.1 - 0.025 14.6 1.2 2 8.4 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2670) DUF627 PF04781.7 ETO06084.1 - 0.057 13.0 6.1 3.9 7.1 0.1 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF627) Mob_Pre PF01076.14 ETO06084.1 - 0.12 11.9 3.2 7.8 6.0 0.0 2.9 2 1 1 3 3 3 0 Plasmid recombination enzyme DUF2225 PF09986.4 ETO06084.1 - 1.3 8.4 10.6 1.4e+02 1.7 7.4 2.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) Fis1_TPR_C PF14853.1 ETO06084.1 - 4.2 7.3 14.7 6.3 6.7 0.1 4.6 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat NACHT PF05729.7 ETO06085.1 - 2.2e-11 43.6 0.4 1.5e-10 40.9 0.2 2.2 2 1 0 2 2 2 1 NACHT domain Mg_chelatase PF01078.16 ETO06085.1 - 0.0025 17.0 0.0 0.045 12.9 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 ETO06085.1 - 0.003 17.5 0.0 0.0073 16.3 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 ETO06085.1 - 0.0031 17.2 0.0 0.0066 16.1 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain NB-ARC PF00931.17 ETO06085.1 - 0.0069 15.2 0.2 0.011 14.6 0.0 1.4 2 0 0 2 2 2 1 NB-ARC domain RNA_helicase PF00910.17 ETO06085.1 - 0.016 15.3 0.3 0.27 11.4 0.0 2.4 2 1 0 2 2 2 0 RNA helicase THDPS_N PF14790.1 ETO06085.1 - 0.018 14.6 0.4 0.033 13.7 0.1 1.5 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal AAA_22 PF13401.1 ETO06085.1 - 0.02 15.0 0.1 0.052 13.6 0.0 1.9 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.4 ETO06085.1 - 0.024 13.6 0.0 0.048 12.6 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 ETO06085.1 - 0.029 14.6 0.0 0.071 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 ETO06085.1 - 0.047 12.9 0.0 0.12 11.5 0.0 1.6 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF2130 PF09903.4 ETO06086.1 - 1.5e-78 263.2 0.2 1.5e-78 263.2 0.1 2.9 2 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2130) DUF148 PF02520.12 ETO06086.1 - 0.18 11.5 25.1 0.33 10.7 1.6 3.4 2 1 1 3 3 3 0 Domain of unknown function DUF148 AAA_13 PF13166.1 ETO06086.1 - 0.19 10.1 28.4 0.015 13.7 16.4 1.5 2 0 0 2 2 2 0 AAA domain LMBR1 PF04791.11 ETO06086.1 - 1.9 6.9 5.4 20 3.6 3.8 2.0 1 1 0 1 1 1 0 LMBR1-like membrane protein Ndc1_Nup PF09531.5 ETO06086.1 - 3.5 5.9 5.3 5.3 5.3 3.7 1.4 1 1 0 1 1 1 0 Nucleoporin protein Ndc1-Nup bZIP_1 PF00170.16 ETO06086.1 - 6 6.8 27.3 7.4 6.6 1.6 5.1 4 1 0 4 4 4 0 bZIP transcription factor Filament PF00038.16 ETO06086.1 - 8.8 5.6 40.8 1.9 7.9 4.9 3.1 2 1 1 3 3 3 0 Intermediate filament protein GTP_EFTU PF00009.22 ETO06087.1 - 2.4e-13 49.9 0.0 1.9e-11 43.7 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PhzC-PhzF PF02567.11 ETO06087.1 - 0.069 12.3 0.0 0.09 11.9 0.0 1.1 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein DUF764 PF05561.6 ETO06087.1 - 0.078 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF764) Gag_spuma PF03276.9 ETO06088.1 - 0.055 11.8 0.0 0.059 11.6 0.0 1.0 1 0 0 1 1 1 0 Spumavirus gag protein Presenilin PF01080.12 ETO06089.1 - 0.34 9.6 2.3 0.44 9.3 1.6 1.2 1 0 0 1 1 1 0 Presenilin DDHD PF02862.12 ETO06089.1 - 0.46 10.2 6.9 0.77 9.5 4.8 1.4 1 0 0 1 1 1 0 DDHD domain CobT PF06213.7 ETO06089.1 - 0.76 8.8 13.1 1.2 8.2 9.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT MMR1 PF08505.5 ETO06089.1 - 1 9.3 11.6 0.096 12.7 5.0 1.5 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein DUF2072 PF09845.4 ETO06089.1 - 1.7 8.5 8.3 4 7.3 5.8 1.6 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Med15 PF09606.5 ETO06089.1 - 4.2 5.4 19.1 5.7 5.0 13.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal HPIP PF15226.1 ETO06091.1 - 0.0078 16.2 0.5 0.014 15.4 0.3 1.4 1 0 0 1 1 1 1 HCF-1 beta-propeller-interacting protein family DUF3245 PF11595.3 ETO06091.1 - 5.8 7.1 10.6 1.7 8.9 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) WD40 PF00400.27 ETO06094.1 - 2.2e-26 90.7 9.1 5.2e-10 38.8 0.1 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO06094.1 - 0.0018 16.5 2.8 0.23 9.5 0.1 3.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 RNase_H PF00075.19 ETO06095.1 - 3.8e-14 53.1 0.0 5.2e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 ETO06095.1 - 0.0073 16.0 0.1 0.017 14.8 0.1 1.7 1 1 0 1 1 1 1 Reverse transcriptase-like zf-LITAF-like PF10601.4 ETO06096.1 - 0.0052 16.6 3.9 0.0052 16.6 2.7 2.3 3 0 0 3 3 3 1 LITAF-like zinc ribbon domain VacA PF02691.10 ETO06096.1 - 0.059 11.0 0.0 0.08 10.5 0.0 1.1 1 0 0 1 1 1 0 Vacuolating cyotoxin DUF3439 PF11921.3 ETO06096.1 - 0.079 12.7 5.1 0.11 12.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) HMG_box_5 PF14887.1 ETO06097.1 - 0.12 12.1 0.3 0.12 12.1 0.2 2.7 2 1 1 3 3 3 0 HMG (high mobility group) box 5 Exo_endo_phos_2 PF14529.1 ETO06098.1 - 2.3e-14 53.0 2.3 5.5e-14 51.7 0.1 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 ETO06098.1 - 0.0037 17.2 0.0 0.0085 16.0 0.0 1.6 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family dUTPase_2 PF08761.6 ETO06098.1 - 0.031 14.3 3.6 0.037 14.1 1.4 1.9 1 1 1 2 2 2 0 dUTPase FAD_syn PF06574.7 ETO06098.1 - 0.059 12.9 0.2 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 FAD synthetase RVT_1 PF00078.22 ETO06099.1 - 2e-21 76.3 1.9 6e-21 74.7 0.2 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Leukemia_assc_2 PF15197.1 ETO06099.1 - 0.023 14.3 0.8 0.11 12.1 0.6 2.2 1 0 0 1 1 1 0 Leukemia-associated protein 2 SPATA24 PF15175.1 ETO06099.1 - 0.099 12.3 4.3 0.21 11.2 0.1 2.9 3 0 0 3 3 3 0 Spermatogenesis-associated protein 24 WD40 PF00400.27 ETO06100.1 - 5.6e-32 108.4 7.3 2e-10 40.1 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO06100.1 - 1e-06 27.1 1.2 0.015 13.5 0.0 2.9 1 1 2 3 3 3 3 Nucleoporin Nup120/160 CRT10 PF08728.5 ETO06100.1 - 0.0042 15.1 4.2 0.017 13.1 2.3 1.9 1 1 1 2 2 2 1 CRT10 Kelch_1 PF01344.20 ETO06101.1 - 1.7e-08 33.8 0.8 0.044 13.3 0.1 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO06101.1 - 4.6e-07 29.7 1.7 0.027 14.6 0.1 3.9 2 1 1 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETO06101.1 - 7.1e-06 25.6 0.2 0.26 11.1 0.0 3.5 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO06101.1 - 0.00061 19.6 4.0 1.6 8.7 0.0 4.5 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO06101.1 - 0.0007 19.2 0.4 4 7.3 0.0 4.0 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 ETO06101.1 - 0.053 13.7 0.1 34 4.7 0.0 3.2 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO06102.1 - 0.0021 17.9 0.1 0.011 15.6 0.0 2.3 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.20 ETO06102.1 - 0.0022 17.4 2.8 0.0099 15.3 0.3 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO06102.1 - 0.006 16.2 0.4 7 6.5 0.0 4.0 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 ETO06102.1 - 0.0073 16.4 0.2 0.13 12.5 0.1 3.0 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO06102.1 - 0.048 13.4 0.4 0.48 10.2 0.0 2.8 3 0 0 3 3 3 0 Galactose oxidase, central domain Zea_mays_MuDR PF05928.6 ETO06102.1 - 0.098 12.0 0.3 0.54 9.6 0.0 2.0 2 0 0 2 2 2 0 Zea mays MURB-like protein (MuDR) Telomere_Sde2 PF13019.1 ETO06103.1 - 4.7e-20 71.9 0.9 6e-20 71.5 0.6 1.1 1 0 0 1 1 1 1 Telomere stability and silencing zf-CCCH_2 PF14608.1 ETO06103.1 - 0.074 13.0 6.6 0.12 12.4 4.6 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Usp PF00582.21 ETO06104.1 - 0.042 14.0 0.0 0.061 13.5 0.0 1.2 1 0 0 1 1 1 0 Universal stress protein family TPR_16 PF13432.1 ETO06105.1 - 0.0027 18.3 0.0 0.0062 17.1 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO06105.1 - 0.039 13.5 0.9 0.077 12.6 0.2 1.8 2 0 0 2 2 2 0 TPR repeat NikR_C PF08753.6 ETO06105.1 - 0.096 12.5 0.7 0.26 11.1 0.5 1.7 1 0 0 1 1 1 0 NikR C terminal nickel binding domain Transposase_24 PF03004.9 ETO06105.1 - 1 9.2 9.2 0.058 13.2 1.9 2.3 3 0 0 3 3 3 0 Plant transposase (Ptta/En/Spm family) DMAP_binding PF06464.6 ETO06105.1 - 9.6 6.8 14.7 0.7 10.5 1.5 3.0 3 0 0 3 3 3 0 DMAP1-binding Domain RVT_1 PF00078.22 ETO06106.1 - 1.4e-12 47.4 2.9 7.5e-07 28.7 0.4 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) WH1 PF00568.18 ETO06106.1 - 0.048 13.3 0.1 0.17 11.5 0.0 2.0 1 0 0 1 1 1 0 WH1 domain Exo_endo_phos_2 PF14529.1 ETO06107.1 - 1.4e-07 31.1 0.0 3.3e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase AHS1 PF02682.11 ETO06107.1 - 0.075 12.4 0.4 2.7 7.3 0.0 2.8 3 0 0 3 3 3 0 Allophanate hydrolase subunit 1 YjcQ PF09639.5 ETO06107.1 - 2.1 8.4 8.0 2.1 8.4 0.2 3.1 2 1 0 3 3 3 0 YjcQ protein DUF4463 PF14703.1 ETO06108.1 - 0.018 15.5 2.0 1.3 9.6 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4463) DUF3626 PF12294.3 ETO06108.1 - 0.032 13.2 0.2 0.052 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) Pox_A_type_inc PF04508.7 ETO06108.1 - 1.5 8.8 6.4 0.16 11.8 0.7 2.3 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat RmuC PF02646.11 ETO06109.1 - 0.0047 15.7 5.1 0.0056 15.5 3.5 1.1 1 0 0 1 1 1 1 RmuC family IFT20 PF14931.1 ETO06109.1 - 0.005 16.7 3.5 0.0084 15.9 2.4 1.5 1 1 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 bZIP_1 PF00170.16 ETO06109.1 - 0.017 15.0 2.8 0.017 15.0 1.9 2.5 1 1 1 2 2 2 0 bZIP transcription factor Occludin_ELL PF07303.8 ETO06109.1 - 0.022 15.5 5.1 0.025 15.3 2.8 1.6 1 1 0 1 1 1 0 Occludin homology domain TSC22 PF01166.13 ETO06109.1 - 0.023 14.6 4.8 1.5 8.8 3.7 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family BLOC1_2 PF10046.4 ETO06109.1 - 0.026 14.6 8.3 0.2 11.8 4.1 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Allexi_40kDa PF05549.6 ETO06109.1 - 0.03 13.5 4.8 0.032 13.5 3.3 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein DegS PF05384.6 ETO06109.1 - 0.038 13.2 5.2 0.047 12.9 3.6 1.1 1 0 0 1 1 1 0 Sensor protein DegS DUF3450 PF11932.3 ETO06109.1 - 0.045 13.0 14.4 0.051 12.8 10.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TetR PF13972.1 ETO06109.1 - 0.049 13.0 2.3 0.055 12.9 1.6 1.3 1 0 0 1 1 1 0 Bacterial transcriptional repressor CCDC-167 PF15188.1 ETO06109.1 - 0.054 13.4 0.7 0.054 13.4 0.5 1.8 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 AATF-Che1 PF13339.1 ETO06109.1 - 0.059 13.5 9.9 0.066 13.3 6.9 1.1 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF1924 PF09086.6 ETO06109.1 - 0.074 13.1 0.3 0.086 12.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1924) Prp19 PF08606.6 ETO06109.1 - 0.085 12.5 4.2 0.18 11.5 2.9 1.7 1 1 0 1 1 1 0 Prp19/Pso4-like XRCC4 PF06632.7 ETO06109.1 - 0.086 11.6 5.0 0.091 11.5 3.5 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 TBPIP PF07106.8 ETO06109.1 - 0.11 11.9 9.6 0.18 11.3 6.6 1.4 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4618 PF15397.1 ETO06109.1 - 0.12 11.7 11.1 0.2 10.9 7.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) HAUS6_N PF14661.1 ETO06109.1 - 0.15 11.3 7.7 0.17 11.2 5.4 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus YPEB PF14620.1 ETO06109.1 - 0.15 11.0 7.9 0.18 10.8 5.5 1.1 1 0 0 1 1 1 0 YpeB sporulation DUF1664 PF07889.7 ETO06109.1 - 0.15 11.8 4.5 0.14 11.9 2.4 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.4 ETO06109.1 - 0.19 11.5 10.6 0.31 10.8 7.3 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.2 ETO06109.1 - 0.2 11.4 11.5 0.3 10.9 8.0 1.5 1 1 0 1 1 1 0 Tropomyosin like IFT57 PF10498.4 ETO06109.1 - 0.21 10.3 10.7 0.22 10.2 7.4 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Seryl_tRNA_N PF02403.17 ETO06109.1 - 0.22 11.5 7.0 0.21 11.5 3.0 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GvpG PF05120.7 ETO06109.1 - 0.32 10.8 2.7 0.52 10.1 1.8 1.5 1 1 0 1 1 1 0 Gas vesicle protein G DUF904 PF06005.7 ETO06109.1 - 0.34 11.2 14.8 1.4 9.2 10.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF3810 PF12725.2 ETO06109.1 - 0.4 9.5 3.5 0.46 9.3 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) THOC7 PF05615.8 ETO06109.1 - 0.62 10.3 8.9 1.2 9.3 6.2 1.7 1 1 0 1 1 1 0 Tho complex subunit 7 DUF342 PF03961.8 ETO06109.1 - 0.64 8.3 9.1 0.63 8.3 6.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Adeno_PIX PF03955.9 ETO06109.1 - 0.67 10.5 5.2 0.25 11.9 1.9 1.5 2 0 0 2 2 1 0 Adenovirus hexon-associated protein (IX) DUF724 PF05266.9 ETO06109.1 - 0.74 9.3 7.8 0.18 11.3 2.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Rootletin PF15035.1 ETO06109.1 - 0.75 9.7 14.7 0.66 9.9 8.4 1.9 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion APG6 PF04111.7 ETO06109.1 - 0.86 8.5 14.2 0.89 8.5 9.8 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 ETO06109.1 - 0.9 9.9 9.4 5.6 7.3 6.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Laminin_II PF06009.7 ETO06109.1 - 0.96 9.2 7.9 1.6 8.4 5.5 1.5 1 1 0 1 1 1 0 Laminin Domain II Spc7 PF08317.6 ETO06109.1 - 1 7.9 11.9 1.1 7.8 8.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein V-SNARE PF05008.10 ETO06109.1 - 1.1 9.4 8.7 1.1 9.4 5.2 1.7 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus YlqD PF11068.3 ETO06109.1 - 1.1 9.2 16.9 1.3 9.0 10.4 1.8 1 1 0 1 1 1 0 YlqD protein Phage_GPO PF05929.6 ETO06109.1 - 1.2 8.3 5.9 1.2 8.3 4.1 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Spc24 PF08286.6 ETO06109.1 - 1.6 8.4 9.4 1.5 8.5 5.5 1.8 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF3573 PF12097.3 ETO06109.1 - 1.7 7.1 6.5 1.7 7.1 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) WXG100 PF06013.7 ETO06109.1 - 1.8 8.6 9.6 4.9 7.2 6.4 2.0 1 1 0 1 1 1 0 Proteins of 100 residues with WXG ADIP PF11559.3 ETO06109.1 - 1.8 8.4 15.0 2.7 7.8 10.4 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 ETO06109.1 - 2.4 7.7 12.9 3.3 7.2 9.0 1.3 1 0 0 1 1 1 0 IncA protein DUF3552 PF12072.3 ETO06109.1 - 2.5 7.2 11.4 2.5 7.2 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) TMF_DNA_bd PF12329.3 ETO06109.1 - 3.9 7.3 11.2 15 5.4 7.8 2.1 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Nnf1 PF03980.9 ETO06109.1 - 4.2 7.4 12.2 0.7 9.9 0.5 2.4 1 1 1 2 2 2 0 Nnf1 UPF0449 PF15136.1 ETO06109.1 - 4.4 7.5 7.5 44 4.3 4.4 2.4 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 Baculo_LEF-11 PF06385.7 ETO06109.1 - 4.4 7.4 6.5 2.6 8.1 0.3 2.1 1 1 1 2 2 2 0 Baculovirus LEF-11 protein SecD-TM1 PF13721.1 ETO06109.1 - 4.5 7.5 7.5 2.6 8.3 3.7 1.7 1 1 1 2 2 2 0 SecD export protein N-terminal TM region V_ATPase_I PF01496.14 ETO06109.1 - 6.3 4.5 7.7 6.4 4.4 5.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.11 ETO06109.1 - 6.6 5.1 5.8 6.2 5.2 4.0 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2968 PF11180.3 ETO06109.1 - 6.6 6.0 17.3 18 4.6 12.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) SlyX PF04102.7 ETO06109.1 - 6.7 7.1 9.5 18 5.8 6.6 1.9 1 1 0 1 1 1 0 SlyX NPV_P10 PF05531.7 ETO06109.1 - 6.7 7.0 9.6 4 7.7 4.4 1.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein HALZ PF02183.13 ETO06109.1 - 8.3 6.2 11.1 2.8 7.7 1.6 3.0 1 1 2 3 3 3 0 Homeobox associated leucine zipper Rotamase PF00639.16 ETO06110.1 - 4.1e-18 65.8 0.0 6.2e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 ETO06110.1 - 3.6e-14 53.0 0.1 6.1e-14 52.2 0.1 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 ETO06110.1 - 6.3e-06 26.8 0.0 9.3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain DUF2207 PF09972.4 ETO06110.1 - 0.00076 18.1 0.0 0.00087 17.9 0.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) NDUFA12 PF05071.11 ETO06111.1 - 0.0016 18.8 1.4 0.0016 18.8 0.9 2.8 2 2 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Peroxidase_2 PF01328.12 ETO06111.1 - 0.13 10.8 0.2 0.17 10.4 0.2 1.1 1 0 0 1 1 1 0 Peroxidase, family 2 DUF4085 PF13315.1 ETO06111.1 - 1.1 8.5 14.8 1.4 8.1 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) Mcp5_PH PF12814.2 ETO06112.1 - 3e-07 30.3 0.0 1.1e-06 28.6 0.0 2.0 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology SR-25 PF10500.4 ETO06112.1 - 0.0049 16.3 14.4 0.0049 16.3 10.0 2.9 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein RP-C_C PF11800.3 ETO06112.1 - 1.3 8.6 11.3 2.7 7.6 3.6 2.8 2 0 0 2 2 2 0 Replication protein C C-terminal region FAD_binding_2 PF00890.19 ETO06113.1 - 7.6e-74 249.0 0.3 1.5e-45 155.8 0.0 2.1 1 1 1 2 2 2 2 FAD binding domain Succ_DH_flav_C PF02910.15 ETO06113.1 - 8.7e-46 154.9 0.3 1.3e-45 154.4 0.2 1.2 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term RPW8 PF05659.6 ETO06114.1 - 0.00085 18.8 1.4 0.0011 18.5 0.3 1.6 1 1 0 1 1 1 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 IncA PF04156.9 ETO06114.1 - 0.038 13.5 8.5 0.057 13.0 5.9 1.3 1 0 0 1 1 1 0 IncA protein DUF3573 PF12097.3 ETO06114.1 - 0.068 11.7 3.3 0.08 11.5 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Seryl_tRNA_N PF02403.17 ETO06114.1 - 0.14 12.1 10.4 0.098 12.6 5.7 1.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.6 ETO06114.1 - 0.47 9.0 11.7 0.55 8.8 8.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein BLOC1_2 PF10046.4 ETO06114.1 - 0.55 10.4 8.0 0.56 10.3 3.6 2.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_p24 PF05073.7 ETO06114.1 - 0.73 9.3 5.4 2.1 7.9 3.7 1.7 1 1 0 1 1 1 0 Baculovirus P24 capsid protein APG6 PF04111.7 ETO06114.1 - 0.93 8.4 11.9 1.1 8.2 8.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 FlxA PF14282.1 ETO06114.1 - 2.3 8.2 15.5 3.7 7.5 10.8 1.4 1 0 0 1 1 1 0 FlxA-like protein DUF342 PF03961.8 ETO06114.1 - 2.7 6.2 12.8 3.5 5.9 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4407 PF14362.1 ETO06114.1 - 2.9 6.7 6.4 3.6 6.4 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Synaptobrevin PF00957.16 ETO06114.1 - 3 7.5 6.1 14 5.3 3.8 2.1 2 0 0 2 2 2 0 Synaptobrevin DUF724 PF05266.9 ETO06114.1 - 4.4 6.8 11.1 6.5 6.3 7.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ADIP PF11559.3 ETO06114.1 - 6 6.7 17.9 9.8 6.0 12.4 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Mnd1 PF03962.10 ETO06114.1 - 6.4 6.3 14.1 7.4 6.1 9.2 1.4 1 1 0 1 1 1 0 Mnd1 family Atg14 PF10186.4 ETO06114.1 - 7.4 5.4 17.7 9 5.1 12.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 WD40 PF00400.27 ETO06115.1 - 6.7e-54 177.9 7.6 1.2e-11 43.9 0.1 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO06115.1 - 2.2e-09 36.0 3.4 0.051 11.7 0.0 4.9 1 1 4 5 5 5 5 Nucleoporin Nup120/160 Pentapeptide_4 PF13599.1 ETO06115.1 - 2.6e-05 23.9 0.1 5.8e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETO06115.1 - 3.3e-05 23.0 0.4 0.00047 19.3 0.1 2.3 1 1 1 2 2 2 1 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 ETO06115.1 - 0.0011 18.7 1.8 0.0039 17.0 0.6 2.4 2 1 0 2 2 2 1 Pentapeptide repeats (9 copies) SGL PF08450.7 ETO06115.1 - 0.0031 16.9 0.2 1.3 8.2 0.0 2.7 1 1 2 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region Cytochrom_D1 PF02239.11 ETO06115.1 - 0.011 14.1 0.4 0.35 9.0 0.1 2.4 2 1 1 3 3 3 0 Cytochrome D1 heme domain DPPIV_N PF00930.16 ETO06115.1 - 0.046 12.2 0.0 3.6 6.0 0.0 2.4 1 1 1 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.7 ETO06115.1 - 0.09 12.4 1.1 17 5.1 0.1 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF1938 PF09153.5 ETO06115.1 - 0.1 12.4 0.1 19 5.1 0.0 2.7 2 1 0 3 3 3 0 Domain of unknown function (DUF1938) Sod_Fe_C PF02777.13 ETO06118.1 - 1e-33 115.3 1.7 1e-33 115.3 1.2 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 ETO06118.1 - 0.0045 17.2 0.1 0.011 16.0 0.1 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Ran_BP1 PF00638.13 ETO06119.1 - 2.9e-06 27.3 0.0 4.2e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain Macoilin PF09726.4 ETO06120.1 - 1.5 7.0 12.7 4.4 5.4 7.7 2.2 2 0 0 2 2 2 0 Transmembrane protein DUF2400 PF09674.5 ETO06121.1 - 0.088 12.4 5.6 0.068 12.8 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) LexA_DNA_bind PF01726.11 ETO06121.1 - 0.13 11.8 0.1 19 4.9 0.0 2.5 2 0 0 2 2 2 0 LexA DNA binding domain PH PF00169.24 ETO06123.1 - 1.4e-12 47.6 0.2 4e-12 46.2 0.1 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 ETO06123.1 - 2.2e-08 34.3 0.4 9.3e-08 32.3 0.3 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 ETO06123.1 - 2.8e-08 33.5 0.5 3.1e-07 30.2 0.4 2.7 1 1 0 1 1 1 1 PH domain PH_8 PF15409.1 ETO06123.1 - 1.9e-07 31.0 0.3 1.1e-06 28.6 0.2 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.1 ETO06123.1 - 0.00025 21.1 0.1 0.0011 19.0 0.1 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain SH3_1 PF00018.23 ETO06123.1 - 0.07 12.5 3.3 0.1 11.9 0.7 2.3 2 0 0 2 2 2 0 SH3 domain Med4 PF10018.4 ETO06123.1 - 0.093 12.1 6.7 0.15 11.4 4.7 1.3 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Spc7 PF08317.6 ETO06123.1 - 0.097 11.3 6.1 0.2 10.2 4.2 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2968 PF11180.3 ETO06123.1 - 0.13 11.6 5.3 0.22 10.8 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF4201 PF13870.1 ETO06123.1 - 0.15 11.4 10.1 0.081 12.3 4.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) IncA PF04156.9 ETO06123.1 - 0.46 10.0 6.8 0.72 9.4 4.7 1.3 1 0 0 1 1 1 0 IncA protein ADIP PF11559.3 ETO06123.1 - 1.1 9.1 7.3 2.6 7.9 5.1 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.3 ETO06123.1 - 1.2 9.0 12.3 0.83 9.5 5.3 3.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding WD40 PF00400.27 ETO06124.1 - 6.7e-26 89.1 10.3 7.1e-08 32.0 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat PD40 PF07676.7 ETO06124.1 - 1.6e-11 43.6 0.8 0.12 12.1 0.2 5.6 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat eIF2A PF08662.6 ETO06124.1 - 8.9e-08 32.0 0.5 3.1e-06 27.0 0.0 2.8 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 ETO06124.1 - 0.00082 18.5 0.6 5.8 5.9 0.0 3.3 1 1 2 3 3 3 2 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 ETO06124.1 - 0.0021 17.5 0.0 0.0072 15.8 0.0 1.8 2 1 0 2 2 2 1 PQQ-like domain Proteasome_A_N PF10584.4 ETO06124.1 - 0.017 14.4 2.4 16 4.9 0.0 4.5 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature DUF3261 PF11659.3 ETO06124.1 - 0.032 13.8 0.0 19 4.8 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3261) DPPIV_N PF00930.16 ETO06124.1 - 0.053 12.1 0.0 12 4.3 0.0 3.4 1 1 3 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region IncA PF04156.9 ETO06125.1 - 0.2 11.1 4.5 0.25 10.9 3.1 1.1 1 0 0 1 1 1 0 IncA protein DUF3843 PF12954.2 ETO06125.1 - 1.2 8.0 8.2 4.4 6.2 5.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3843) TPR_12 PF13424.1 ETO06126.1 - 3.3e-49 164.7 4.5 1.1e-20 73.3 0.1 4.2 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO06126.1 - 3.1e-26 89.8 38.4 1.4e-08 34.0 0.6 6.8 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETO06126.1 - 1.7e-25 88.1 0.0 2.8e-07 30.2 0.0 5.3 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO06126.1 - 1.5e-24 85.4 19.3 6.3e-13 48.1 2.0 4.7 3 2 1 4 4 4 4 TPR repeat TPR_7 PF13176.1 ETO06126.1 - 8.7e-24 81.3 10.1 5.2e-05 22.7 0.0 6.0 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO06126.1 - 4.5e-21 72.9 39.2 2.9e-05 23.5 1.4 6.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETO06126.1 - 1.7e-20 71.2 26.3 3.6e-05 23.3 0.1 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 ETO06126.1 - 4.5e-12 45.1 7.7 0.00017 21.5 0.0 6.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO06126.1 - 9.2e-10 38.9 0.1 0.0025 18.4 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_3 PF07720.7 ETO06126.1 - 9.2e-07 28.5 15.8 0.0012 18.6 0.2 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO06126.1 - 1.3e-06 28.4 8.7 0.00047 20.2 1.4 4.0 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 ETO06126.1 - 6.7e-06 26.2 0.0 1.5 9.6 0.0 5.1 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO06126.1 - 2.9e-05 24.2 12.0 1.4 9.5 0.1 6.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO06126.1 - 6.7e-05 23.1 0.3 0.04 14.2 0.0 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat DUF896 PF05979.7 ETO06126.1 - 0.014 14.9 0.2 0.042 13.4 0.1 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) Hydrolase_6 PF13344.1 ETO06126.1 - 0.5 10.2 2.9 0.99 9.3 0.5 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Sel1 PF08238.7 ETO06126.1 - 8.3 7.2 12.3 39 5.0 0.5 4.5 4 0 0 4 4 4 0 Sel1 repeat DSPc PF00782.15 ETO06128.1 - 6.2e-08 32.3 0.1 9.2e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 ETO06128.1 - 4e-06 26.3 0.0 4.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 ETO06128.1 - 0.00023 21.4 0.3 0.00038 20.7 0.2 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 ETO06128.1 - 0.011 15.7 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate WD40 PF00400.27 ETO06131.1 - 3.4e-55 182.0 24.8 1.1e-11 44.1 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO06131.1 - 7.5e-10 37.5 9.5 0.0049 15.0 0.0 4.8 2 2 3 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO06131.1 - 0.00029 19.7 14.0 0.54 8.9 2.9 4.8 1 1 1 2 2 2 2 Nup133 N terminal like F-box-like PF12937.2 ETO06132.1 - 0.003 17.2 0.2 0.016 14.8 0.1 2.3 3 0 0 3 3 3 1 F-box-like FANCL_C PF11793.3 ETO06132.1 - 0.016 15.1 0.1 0.04 13.8 0.1 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain WD40 PF00400.27 ETO06133.1 - 5.7e-52 171.8 16.7 3.6e-10 39.3 0.2 7.1 6 1 1 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO06133.1 - 6.2e-11 41.1 2.2 0.052 11.6 0.2 5.0 2 2 1 4 4 4 4 Nucleoporin Nup120/160 IBR PF01485.16 ETO06135.1 - 0.14 12.0 3.1 0.34 10.7 2.1 1.9 1 1 0 1 1 1 0 IBR domain DUF2177 PF09945.4 ETO06136.1 - 0.21 11.5 1.6 26 4.8 0.9 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2177) WD40 PF00400.27 ETO06137.1 - 1.1e-12 47.3 2.0 5.6e-12 45.0 0.3 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO06137.1 - 4.8e-05 21.7 0.1 5.1e-05 21.6 0.1 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 TPR_8 PF13181.1 ETO06138.1 - 1.9e-77 249.3 44.6 1.4e-06 27.6 0.0 18.7 18 1 1 19 19 19 15 Tetratricopeptide repeat TPR_1 PF00515.23 ETO06138.1 - 4e-68 222.4 70.7 1.7e-07 30.5 0.1 19.0 19 0 0 19 19 19 13 Tetratricopeptide repeat TPR_2 PF07719.12 ETO06138.1 - 1e-66 215.5 62.8 2.7e-06 26.8 0.0 19.1 18 1 1 19 19 19 14 Tetratricopeptide repeat TPR_16 PF13432.1 ETO06138.1 - 1.7e-66 219.6 24.6 2.9e-08 34.1 0.0 11.3 7 3 6 13 13 13 12 Tetratricopeptide repeat TPR_11 PF13414.1 ETO06138.1 - 9e-66 217.4 40.6 8.2e-11 41.4 0.0 12.0 5 4 7 13 13 13 13 TPR repeat TPR_14 PF13428.1 ETO06138.1 - 5.6e-65 209.8 26.5 5.2e-06 26.6 0.1 18.5 4 3 15 19 19 19 14 Tetratricopeptide repeat TPR_19 PF14559.1 ETO06138.1 - 1.9e-60 201.0 37.3 2.4e-09 37.3 0.1 11.8 4 4 6 12 12 12 12 Tetratricopeptide repeat TPR_17 PF13431.1 ETO06138.1 - 1.4e-54 177.7 26.5 2.8e-05 23.9 0.2 15.6 16 0 0 16 16 16 10 Tetratricopeptide repeat TPR_12 PF13424.1 ETO06138.1 - 9.7e-53 176.0 39.4 1.7e-08 34.3 0.1 11.7 4 2 10 14 14 14 12 Tetratricopeptide repeat TPR_7 PF13176.1 ETO06138.1 - 1.3e-46 152.7 26.6 0.00016 21.1 0.0 16.6 17 0 0 17 17 17 11 Tetratricopeptide repeat TPR_6 PF13174.1 ETO06138.1 - 1.8e-33 112.6 39.4 0.082 13.3 0.0 16.9 17 0 0 17 17 17 9 Tetratricopeptide repeat TPR_20 PF14561.1 ETO06138.1 - 5.7e-18 64.8 26.3 0.0025 17.8 0.2 10.6 5 3 5 11 11 11 7 Tetratricopeptide repeat Apc3 PF12895.2 ETO06138.1 - 1.6e-16 60.2 30.3 0.009 16.1 0.0 8.4 3 2 5 8 8 8 7 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 ETO06138.1 - 1.8e-14 53.3 3.6 0.00027 20.7 0.0 7.9 6 2 3 9 9 8 3 Tetratricopeptide repeat TPR_4 PF07721.9 ETO06138.1 - 3.4e-13 48.6 0.0 13 6.5 0.0 11.6 14 0 0 14 14 11 0 Tetratricopeptide repeat NARP1 PF12569.3 ETO06138.1 - 9.3e-13 47.7 24.6 0.012 14.4 5.4 6.8 1 1 5 7 7 7 5 NMDA receptor-regulated protein 1 TPR_21 PF09976.4 ETO06138.1 - 3.4e-12 46.5 25.9 1.4e-05 25.0 1.3 7.6 3 2 4 8 8 8 4 Tetratricopeptide repeat FAT PF02259.18 ETO06138.1 - 1.3e-10 40.8 7.8 0.17 10.8 0.0 9.5 3 3 3 6 6 6 3 FAT domain TOM20_plant PF06552.7 ETO06138.1 - 2.3e-07 30.5 15.0 1.8 8.1 0.0 9.5 3 3 5 10 10 10 2 Plant specific mitochondrial import receptor subunit TOM20 TPR_10 PF13374.1 ETO06138.1 - 4.8e-06 26.3 27.4 1.7 8.6 0.0 12.4 15 0 0 15 15 13 1 Tetratricopeptide repeat TPR_15 PF13429.1 ETO06138.1 - 4.3e-05 22.7 18.4 0.24 10.4 0.0 6.0 2 2 4 6 6 6 2 Tetratricopeptide repeat DUF4248 PF14053.1 ETO06138.1 - 0.00021 20.7 1.1 1.3 8.6 0.0 5.6 5 2 2 7 7 7 1 Domain of unknown function (DUF4248) PPR PF01535.15 ETO06138.1 - 0.0012 18.6 16.3 5.1 7.2 0.0 8.2 10 0 0 10 10 8 0 PPR repeat MazG PF03819.12 ETO06138.1 - 0.0019 18.1 3.1 7 6.6 0.0 6.1 5 1 1 6 6 6 0 MazG nucleotide pyrophosphohydrolase domain PPR_3 PF13812.1 ETO06138.1 - 0.0038 17.3 0.0 27 5.3 0.0 5.8 5 0 0 5 5 4 0 Pentatricopeptide repeat domain DUF2300 PF10062.4 ETO06138.1 - 0.019 14.7 0.0 0.66 9.7 0.0 2.7 2 1 1 3 3 3 0 Predicted secreted protein (DUF2300) DUF2508 PF10704.4 ETO06138.1 - 0.061 13.5 10.3 0.94 9.7 0.9 4.8 4 1 1 5 5 4 0 Protein of unknown function (DUF2508) Alkyl_sulf_dimr PF14863.1 ETO06138.1 - 0.31 11.2 15.6 40 4.4 0.0 7.0 6 2 4 10 10 9 0 Alkyl sulfatase dimerisation Mad3_BUB1_I PF08311.7 ETO06138.1 - 2.7 7.8 11.0 34 4.2 0.0 5.6 6 1 0 6 6 6 0 Mad3/BUB1 homology region 1 Ank_2 PF12796.2 ETO06139.1 - 1.4e-37 127.9 5.0 1.2e-16 60.8 0.1 3.7 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETO06139.1 - 2.9e-35 118.3 0.6 4.6e-06 26.1 0.0 6.6 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 ETO06139.1 - 2.3e-26 91.6 5.2 3.9e-07 30.4 0.1 5.3 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO06139.1 - 3.1e-24 84.4 3.1 7e-10 38.8 0.1 5.3 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO06139.1 - 6.9e-22 75.3 5.3 3.4e-05 23.6 0.1 6.8 6 0 0 6 6 6 5 Ankyrin repeat Uds1 PF15456.1 ETO06140.1 - 0.00015 21.7 3.8 0.00015 21.7 2.6 3.6 3 1 0 3 3 3 1 Up-regulated During Septation IFT43 PF15305.1 ETO06141.1 - 3.7 7.5 6.8 4.5 7.2 4.7 1.1 1 0 0 1 1 1 0 Intraflagellar transport protein 43 WD40 PF00400.27 ETO06142.1 - 8.9e-44 145.8 13.9 5.8e-13 48.1 0.0 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO06142.1 - 2.5e-11 42.4 1.9 0.0002 19.6 0.1 4.0 1 1 3 4 4 4 4 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO06142.1 - 0.016 15.1 0.1 0.26 11.2 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3601) WD40 PF00400.27 ETO06144.1 - 3.6e-61 201.0 7.8 7.2e-13 47.8 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 ETO06144.1 - 1.8e-10 40.8 0.2 2e-05 24.3 0.1 3.2 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO06144.1 - 1.2e-09 36.8 2.3 0.014 13.5 0.0 4.2 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO06144.1 - 3.8e-06 25.9 3.1 0.49 9.0 0.1 4.0 1 1 3 4 4 4 3 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO06144.1 - 1.9e-05 23.1 0.3 0.35 9.1 0.1 3.0 1 1 1 3 3 3 3 Cytochrome D1 heme domain PD40 PF07676.7 ETO06144.1 - 6.7e-05 22.4 8.2 3.8 7.2 0.0 6.3 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat Nop10p PF04135.7 ETO06144.1 - 0.0044 16.7 0.3 3.4 7.4 0.0 3.0 3 0 0 3 3 3 1 Nucleolar RNA-binding protein, Nop10p family PQQ_2 PF13360.1 ETO06144.1 - 0.0052 16.2 0.0 0.12 11.7 0.0 2.6 1 1 2 3 3 3 1 PQQ-like domain Resistin PF06954.6 ETO06144.1 - 0.072 13.3 0.0 22 5.3 0.0 3.2 2 1 1 3 3 3 0 Resistin PI3Ka PF00613.15 ETO06145.1 - 7.7e-23 80.6 1.7 2.1e-22 79.2 0.1 2.1 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 ETO06145.1 - 1.1e-21 77.4 0.7 6.1e-21 74.9 0.5 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase tRNA-synt_2b PF00587.20 ETO06145.1 - 0.0057 16.2 0.6 0.078 12.5 0.4 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) C4 PF01413.14 ETO06145.1 - 0.087 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 C-terminal tandem repeated domain in type 4 procollagen RRP7 PF12923.2 ETO06146.1 - 0.059 13.4 0.0 0.092 12.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) PRP1_N PF06424.7 ETO06148.1 - 0.085 13.1 2.7 0.14 12.4 1.9 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal TRM13 PF05206.9 ETO06149.1 - 3.3e-16 59.3 1.0 6.7e-12 45.1 0.2 2.6 1 1 1 2 2 2 2 Methyltransferase TRM13 Methyltransf_32 PF13679.1 ETO06149.1 - 0.00058 19.5 0.3 0.0013 18.4 0.2 1.5 1 1 1 2 2 2 1 Methyltransferase domain Kelch_6 PF13964.1 ETO06150.1 - 2.7e-06 27.2 2.0 3 8.1 0.1 5.0 3 1 1 4 4 4 3 Kelch motif Kelch_1 PF01344.20 ETO06150.1 - 1e-05 24.9 4.0 0.029 13.8 0.2 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO06150.1 - 0.0013 18.8 0.1 0.16 12.1 0.0 3.8 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO06150.1 - 0.0096 15.6 2.6 2.5 7.9 0.0 4.4 3 2 1 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO06150.1 - 0.035 14.0 0.3 11 6.1 0.1 4.0 4 0 0 4 4 4 0 Kelch motif WD40 PF00400.27 ETO06151.1 - 6.5e-15 54.3 6.3 2.1e-08 33.7 0.2 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat WD40 PF00400.27 ETO06153.1 - 8.7e-68 221.9 19.8 1.3e-12 47.0 0.1 8.6 7 1 1 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO06153.1 - 6e-10 37.8 3.7 0.0035 15.5 0.1 4.3 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Kelch_2 PF07646.10 ETO06153.1 - 2.5e-05 23.8 2.8 0.21 11.3 0.2 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO06153.1 - 0.00012 21.5 5.9 0.23 11.0 0.3 4.2 4 0 0 4 4 4 2 Kelch motif Cytochrom_D1 PF02239.11 ETO06153.1 - 0.00013 20.4 0.2 0.022 13.0 0.0 3.2 3 0 0 3 3 3 1 Cytochrome D1 heme domain Kelch_4 PF13418.1 ETO06153.1 - 0.00096 18.8 5.8 0.49 10.2 0.4 4.4 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO06153.1 - 0.0018 18.3 9.9 2.3 8.5 0.0 5.7 6 0 0 6 6 6 1 Kelch motif Kelch_5 PF13854.1 ETO06153.1 - 0.0023 17.8 0.5 14 5.8 0.2 4.2 4 0 0 4 4 4 0 Kelch motif PQQ_2 PF13360.1 ETO06153.1 - 0.028 13.8 0.0 0.32 10.4 0.0 2.6 1 1 0 1 1 1 0 PQQ-like domain Resistin PF06954.6 ETO06153.1 - 0.088 13.0 0.3 40 4.5 0.0 4.1 3 1 1 4 4 4 0 Resistin PD40 PF07676.7 ETO06153.1 - 0.098 12.3 1.9 7.5 6.3 0.1 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 ETO06154.1 - 2.1e-85 277.8 16.8 1e-13 50.5 0.0 7.0 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO06154.1 - 1.1e-11 43.6 4.5 0.1 10.6 0.0 5.4 1 1 5 6 6 6 5 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO06154.1 - 3e-07 30.1 0.3 0.0093 15.4 0.0 3.5 1 1 1 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 ETO06154.1 - 3.4e-07 29.3 9.4 0.3 9.7 0.2 5.6 1 1 5 6 6 6 4 Nup133 N terminal like PD40 PF07676.7 ETO06154.1 - 6.9e-06 25.6 9.2 5.1 6.8 0.1 6.1 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO06154.1 - 0.00018 19.9 0.1 0.0018 16.6 0.0 2.3 1 1 1 2 2 2 2 Cytochrome D1 heme domain PQQ_3 PF13570.1 ETO06154.1 - 0.0025 18.0 0.1 0.9 9.8 0.0 3.7 4 0 0 4 4 4 1 PQQ-like domain Resistin PF06954.6 ETO06154.1 - 0.0057 16.9 0.0 7.3 6.9 0.0 3.2 2 1 1 3 3 3 1 Resistin Nbas_N PF15492.1 ETO06154.1 - 0.016 14.3 0.9 2.8 6.9 0.0 3.5 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 ETO06154.1 - 0.036 13.3 4.7 28 4.1 0.0 4.6 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature DUF1258 PF06869.7 ETO06154.1 - 0.051 12.6 1.7 5 6.1 0.1 3.0 2 1 1 4 4 4 0 Protein of unknown function (DUF1258) Kelch_6 PF13964.1 ETO06155.1 - 2.3e-07 30.6 3.9 0.09 12.9 0.1 4.7 4 1 1 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO06155.1 - 1.6e-06 27.7 0.3 0.012 15.3 0.1 3.4 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO06155.1 - 6.6e-06 25.5 8.2 0.00069 19.1 0.4 4.2 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO06155.1 - 9.2e-05 22.0 3.2 0.44 10.3 0.1 4.5 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 ETO06155.1 - 0.00019 21.3 1.9 0.41 10.6 0.0 4.0 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 ETO06155.1 - 0.004 17.2 0.8 0.065 13.4 0.0 3.2 4 0 0 4 4 4 1 Galactose oxidase, central domain Methyltransf_FA PF12248.3 ETO06155.1 - 0.013 15.5 2.9 1.4 8.9 0.0 3.2 4 0 0 4 4 4 0 Farnesoic acid 0-methyl transferase Kelch_1 PF01344.20 ETO06156.1 - 0.00019 20.9 0.6 3.6 7.2 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO06156.1 - 0.0023 17.8 0.2 0.22 11.5 0.1 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 ETO06156.1 - 0.0037 17.3 6.6 0.75 10.0 0.0 4.4 5 2 1 6 6 6 2 Kelch motif Kelch_4 PF13418.1 ETO06156.1 - 0.0048 16.6 0.2 0.11 12.2 0.0 3.2 3 0 0 3 3 3 1 Galactose oxidase, central domain MatP PF06303.7 ETO06156.1 - 0.044 13.6 0.1 0.075 12.9 0.1 1.4 1 0 0 1 1 1 0 Organiser of macrodomain of Terminus of chromosome Helicase_C PF00271.26 ETO06157.1 - 7.9e-06 25.6 0.1 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain XRN_N PF03159.13 ETO06158.1 - 2.2e-12 46.9 0.1 2.2e-12 46.9 0.1 2.5 2 1 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus RNase_H2-Ydr279 PF09468.5 ETO06158.1 - 0.0034 16.6 7.9 0.0038 16.4 5.5 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Nop14 PF04147.7 ETO06158.1 - 0.013 13.4 24.5 0.016 13.1 17.0 1.0 1 0 0 1 1 1 0 Nop14-like family GAGA_bind PF06217.7 ETO06158.1 - 0.034 14.1 10.6 0.04 13.8 7.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF1183 PF06682.7 ETO06158.1 - 0.08 12.5 2.9 0.092 12.3 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) SprA-related PF12118.3 ETO06158.1 - 0.097 11.9 16.3 0.12 11.6 11.3 1.1 1 0 0 1 1 1 0 SprA-related family Herpes_DNAp_acc PF04929.7 ETO06158.1 - 0.14 11.0 9.4 0.19 10.6 6.5 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Hid1 PF12722.2 ETO06158.1 - 0.25 8.9 16.6 0.31 8.6 11.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ORC6 PF05460.8 ETO06158.1 - 0.25 10.3 7.9 0.3 10.1 5.5 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF2201_N PF13203.1 ETO06158.1 - 0.31 10.1 12.2 0.42 9.7 8.5 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Zip PF02535.17 ETO06158.1 - 0.35 9.8 2.8 0.39 9.6 2.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SDA1 PF05285.7 ETO06158.1 - 0.37 10.0 25.8 0.45 9.7 17.9 1.2 1 0 0 1 1 1 0 SDA1 CENP-T PF15511.1 ETO06158.1 - 0.43 9.7 11.8 0.49 9.5 8.2 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T GPCR_chapero_1 PF11904.3 ETO06158.1 - 0.66 9.0 12.5 0.81 8.7 8.7 1.2 1 0 0 1 1 1 0 GPCR-chaperone Daxx PF03344.10 ETO06158.1 - 1.2 7.5 22.5 1.4 7.2 15.6 1.1 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 ETO06158.1 - 1.4 8.2 24.4 2.2 7.6 16.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Apt1 PF10351.4 ETO06158.1 - 1.8 7.2 17.4 2.4 6.9 12.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Neur_chan_memb PF02932.11 ETO06158.1 - 3 7.6 7.4 3.7 7.3 5.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Raftlin PF15250.1 ETO06158.1 - 3 6.2 11.1 4 5.8 7.7 1.1 1 0 0 1 1 1 0 Raftlin MDFI PF15316.1 ETO06158.1 - 5.2 7.0 5.5 7 6.6 3.8 1.2 1 0 0 1 1 1 0 MyoD family inhibitor ETRAMP PF09716.5 ETO06158.1 - 6.7 6.7 7.8 14 5.7 5.0 1.9 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) NTP_transf_2 PF01909.18 ETO06159.1 - 1.2e-09 38.3 0.0 4.2e-09 36.6 0.0 1.9 1 1 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 ETO06159.1 - 0.00012 21.9 1.1 0.00031 20.6 0.1 2.2 2 1 0 2 2 2 1 Cid1 family poly A polymerase PAP_central PF04928.12 ETO06159.1 - 0.0048 15.7 0.0 0.0068 15.2 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain zf-rbx1 PF12678.2 ETO06160.1 - 5.1e-10 39.3 18.1 2.6e-09 37.0 12.5 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 ETO06160.1 - 7e-08 32.2 6.0 7e-08 32.2 4.1 2.7 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 ETO06160.1 - 1.7e-05 24.6 8.5 1.7e-05 24.6 5.9 2.8 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO06160.1 - 3.4e-05 23.5 15.2 3.4e-05 23.5 10.6 2.7 3 1 0 3 3 3 1 Ring finger domain zf-HC5HC2H_2 PF13832.1 ETO06160.1 - 0.17 11.8 14.5 0.1 12.5 5.5 2.5 1 1 0 2 2 2 0 PHD-zinc-finger like domain zf-RING_6 PF14835.1 ETO06160.1 - 0.5 10.2 6.8 0.88 9.4 4.0 2.0 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-P11 PF03854.9 ETO06160.1 - 1.5 8.3 11.6 0.33 10.4 4.9 2.3 1 1 1 2 2 2 0 P-11 zinc finger zf-RING_5 PF14634.1 ETO06160.1 - 2.3 7.9 23.4 0.098 12.3 10.2 3.1 2 1 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 ETO06160.1 - 3.9 7.2 26.2 0.16 11.6 11.5 3.1 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Exonuc_X-T_C PF08411.5 ETO06161.1 - 0.039 12.9 3.4 0.026 13.5 0.8 1.7 2 0 0 2 2 2 0 Exonuclease C-terminal RRM_6 PF14259.1 ETO06162.1 - 0.0063 16.4 0.1 0.014 15.3 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO06162.1 - 0.0082 15.7 0.1 0.025 14.1 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3816 PF12822.2 ETO06162.1 - 0.17 11.7 2.0 0.27 11.1 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) Ras PF00071.17 ETO06163.1 - 3.4e-48 163.1 0.0 4.3e-48 162.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO06163.1 - 2.5e-15 57.0 0.0 4.3e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO06163.1 - 3.9e-07 29.4 0.0 5.8e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO06163.1 - 0.0032 16.9 0.0 0.0045 16.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Hormone_6 PF00236.13 ETO06164.1 - 0.017 14.9 0.7 0.032 14.0 0.5 1.5 1 0 0 1 1 1 0 Glycoprotein hormone Exo_endo_phos_2 PF14529.1 ETO06167.1 - 9.4e-08 31.6 0.4 1.2e-07 31.3 0.3 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Hpr_kinase_C PF07475.7 ETO06167.1 - 0.04 13.2 0.2 0.049 12.9 0.2 1.4 1 1 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_14 PF13173.1 ETO06168.1 - 2.1 8.2 5.5 4.1 7.3 3.6 1.7 1 1 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 ETO06169.1 - 4.3e-18 64.5 0.6 9.2e-18 63.4 0.4 1.4 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family Neuropeptide_S PF14993.1 ETO06170.1 - 0.077 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Neuropeptide S precursor protein Semialdhyde_dh PF01118.19 ETO06172.1 - 1.7e-05 25.1 0.1 3.8e-05 23.9 0.1 1.6 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 ETO06172.1 - 2.1e-05 24.6 0.0 0.00098 19.1 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 ETO06172.1 - 5.1e-05 22.3 0.1 9.9e-05 21.3 0.1 1.5 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 ETO06172.1 - 0.00012 22.0 0.0 0.00015 21.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 ETO06172.1 - 0.00015 21.2 0.0 0.00019 20.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 ETO06172.1 - 0.0018 18.4 0.1 0.022 14.8 0.1 2.0 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 ETO06172.1 - 0.0018 17.7 0.0 0.0029 17.0 0.0 1.6 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GARS_N PF02844.10 ETO06172.1 - 0.002 18.5 0.0 0.0061 16.9 0.0 1.7 1 1 1 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain DapB_N PF01113.15 ETO06172.1 - 0.012 15.5 0.2 0.018 14.9 0.1 1.4 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 ETO06172.1 - 0.013 15.2 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 KR domain NmrA PF05368.8 ETO06172.1 - 0.014 14.6 0.1 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family 3Beta_HSD PF01073.14 ETO06172.1 - 0.022 13.4 0.1 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family FadR_C PF07840.7 ETO06172.1 - 0.048 13.2 0.1 0.075 12.6 0.1 1.4 1 1 0 1 1 1 0 FadR C-terminal domain NAD_binding_4 PF07993.7 ETO06172.1 - 0.055 12.3 0.0 0.059 12.2 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Nucleoside_tran PF01733.13 ETO06172.1 - 0.064 12.4 0.2 0.079 12.1 0.1 1.1 1 0 0 1 1 1 0 Nucleoside transporter Saccharop_dh PF03435.13 ETO06172.1 - 0.072 12.0 0.0 0.086 11.7 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF3275 PF11679.3 ETO06172.1 - 0.077 12.6 0.0 0.093 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) RdRP PF05183.7 ETO06173.1 - 4e-62 210.7 1.1 9.6e-61 206.1 0.0 2.0 2 0 0 2 2 2 2 RNA dependent RNA polymerase RdRP PF05183.7 ETO06174.1 - 4.6e-12 45.4 0.1 5.2e-12 45.2 0.1 1.0 1 0 0 1 1 1 1 RNA dependent RNA polymerase Tautomerase_2 PF14552.1 ETO06174.1 - 0.057 13.4 0.5 0.11 12.5 0.3 1.4 1 0 0 1 1 1 0 Tautomerase enzyme RdRP PF05183.7 ETO06175.1 - 3.5e-18 65.6 0.7 6.2e-18 64.8 0.5 1.3 1 1 0 1 1 1 1 RNA dependent RNA polymerase ETRAMP PF09716.5 ETO06175.1 - 3 7.8 10.9 22 5.0 7.5 2.1 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) WD40 PF00400.27 ETO06176.1 - 8.7e-52 171.2 8.5 6.8e-11 41.6 0.0 5.0 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO06176.1 - 1.8e-05 23.0 8.0 0.048 11.7 0.6 3.9 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO06176.1 - 0.00025 19.9 3.6 0.24 10.0 0.0 3.2 2 1 1 3 3 3 3 Nup133 N terminal like Resistin PF06954.6 ETO06176.1 - 0.0022 18.1 0.1 4 7.7 0.0 3.2 3 1 1 4 4 4 2 Resistin DUF1258 PF06869.7 ETO06176.1 - 0.0077 15.3 0.0 0.019 14.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1258) Cu_amine_oxidN1 PF07833.6 ETO06177.1 - 0.11 12.7 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 Copper amine oxidase N-terminal domain WD40 PF00400.27 ETO06178.1 - 3.5e-25 86.9 10.6 3.1e-11 42.6 0.4 4.5 3 1 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO06178.1 - 7.2e-06 24.4 0.1 0.0017 16.5 0.2 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 TypeIII_RM_meth PF12564.3 ETO06178.1 - 0.67 9.9 0.0 0.67 9.9 0.0 3.1 2 1 0 3 3 3 0 Type III restriction/modification enzyme methylation subunit Kelch_6 PF13964.1 ETO06179.1 - 2.1e-05 24.4 0.3 0.014 15.5 0.1 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.20 ETO06179.1 - 0.00034 20.0 1.4 0.061 12.8 0.4 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETO06179.1 - 0.0022 17.6 0.8 3.4 7.5 0.2 3.4 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO06179.1 - 0.0099 15.6 1.0 15 5.5 0.5 3.9 3 1 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 ETO06179.1 - 0.12 12.5 0.0 1.4 9.1 0.0 2.7 3 0 0 3 3 3 0 Galactose oxidase, central domain Hydrolase_like PF13242.1 ETO06180.1 - 0.017 14.8 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 HAD-hyrolase-like DUF4014 PF13198.1 ETO06180.1 - 0.029 14.7 2.5 0.037 14.4 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4014) DUF872 PF05915.7 ETO06181.1 - 5.6 6.8 11.7 2.8 7.8 0.1 2.8 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF872) DUF2951 PF11166.3 ETO06182.1 - 0.0016 18.2 0.6 0.003 17.3 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2951) TRAP_alpha PF03896.11 ETO06182.1 - 0.0017 17.3 0.5 0.0018 17.3 0.4 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit U1snRNP70_N PF12220.3 ETO06182.1 - 0.0048 17.1 3.7 0.0073 16.6 2.5 1.3 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal OATP PF03137.15 ETO06182.1 - 0.0049 14.9 0.0 0.0061 14.6 0.0 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family PcfK PF14058.1 ETO06182.1 - 0.0077 16.3 5.8 0.011 15.8 4.0 1.2 1 0 0 1 1 1 1 PcfK-like protein HNOBA PF07701.9 ETO06182.1 - 0.0087 15.2 1.0 0.0087 15.2 0.7 1.3 2 0 0 2 2 1 1 Heme NO binding associated RR_TM4-6 PF06459.7 ETO06182.1 - 0.017 15.0 5.3 0.021 14.7 3.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BLVR PF06375.6 ETO06182.1 - 0.018 14.8 7.7 0.03 14.1 5.3 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) CENP-B_dimeris PF09026.5 ETO06182.1 - 0.019 15.1 3.0 0.026 14.7 2.0 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4366 PF14283.1 ETO06182.1 - 0.019 14.3 2.2 0.025 14.0 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF3899 PF13038.1 ETO06182.1 - 0.021 14.9 0.2 0.039 14.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) DUF4199 PF13858.1 ETO06182.1 - 0.031 14.1 1.0 0.043 13.7 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) MscS_TM PF12794.2 ETO06182.1 - 0.032 12.8 0.4 0.037 12.6 0.3 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF912 PF06024.7 ETO06182.1 - 0.037 14.0 0.1 0.054 13.5 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Daxx PF03344.10 ETO06182.1 - 0.037 12.5 5.7 0.037 12.5 4.0 1.0 1 0 0 1 1 1 0 Daxx Family TRAP-gamma PF07074.7 ETO06182.1 - 0.046 13.2 0.2 0.065 12.7 0.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Perilipin PF03036.11 ETO06182.1 - 0.051 12.4 0.6 0.063 12.1 0.4 1.1 1 0 0 1 1 1 0 Perilipin family Tom37_C PF11801.3 ETO06182.1 - 0.064 13.1 0.2 0.077 12.8 0.1 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain DUF106 PF01956.11 ETO06182.1 - 0.067 12.7 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF1129 PF06570.6 ETO06182.1 - 0.098 11.9 0.1 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF1510 PF07423.6 ETO06182.1 - 0.11 11.7 7.9 0.15 11.3 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ycf1 PF05758.7 ETO06182.1 - 0.12 10.0 2.1 0.12 10.0 1.5 1.1 1 0 0 1 1 1 0 Ycf1 FAM176 PF14851.1 ETO06182.1 - 0.12 12.0 3.4 0.16 11.6 2.4 1.2 1 0 0 1 1 1 0 FAM176 family DUF913 PF06025.7 ETO06182.1 - 0.12 11.0 0.2 0.15 10.8 0.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF3169 PF11368.3 ETO06182.1 - 0.14 11.2 0.5 0.2 10.8 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3169) Myc_N PF01056.13 ETO06182.1 - 0.17 11.0 2.6 0.2 10.7 1.8 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Sec62 PF03839.11 ETO06182.1 - 0.24 10.7 2.0 0.3 10.4 1.4 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 RNA_pol_Rpc4 PF05132.9 ETO06182.1 - 0.39 10.6 4.6 0.55 10.2 3.2 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF3311 PF11755.3 ETO06182.1 - 0.41 10.2 2.7 0.9 9.1 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) DUF3987 PF13148.1 ETO06182.1 - 0.81 8.1 4.4 0.93 7.9 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) CDC45 PF02724.9 ETO06182.1 - 1.9 6.4 5.9 2.3 6.1 4.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.12 ETO06182.1 - 2 8.1 4.5 2.5 7.8 3.1 1.1 1 0 0 1 1 1 0 DDHD domain Vfa1 PF08432.5 ETO06182.1 - 2.6 8.0 10.9 3.8 7.5 7.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 BSP_II PF05432.6 ETO06182.1 - 2.9 7.0 12.2 3.8 6.6 8.4 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) RNA_pol_3_Rpc31 PF11705.3 ETO06182.1 - 3.7 7.4 12.9 5 6.9 9.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Radial_spoke PF04712.7 ETO06182.1 - 4.4 5.9 11.0 5.1 5.7 7.6 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein PBP_sp32 PF07222.7 ETO06182.1 - 4.7 6.3 12.1 6.4 5.8 8.4 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 YqfQ PF14181.1 ETO06182.1 - 5.3 7.0 9.1 7.8 6.5 6.3 1.2 1 0 0 1 1 1 0 YqfQ-like protein Rad50_zn_hook PF04423.9 ETO06184.1 - 0.043 13.2 0.1 0.098 12.1 0.0 1.6 1 1 0 1 1 1 0 Rad50 zinc hook motif Ion_trans PF00520.26 ETO06185.1 - 3.5e-05 23.1 4.4 3.5e-05 23.1 3.1 1.9 2 0 0 2 2 2 1 Ion transport protein DUF1510 PF07423.6 ETO06185.1 - 0.00031 20.1 2.5 0.00047 19.5 1.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Zip PF02535.17 ETO06185.1 - 0.0014 17.6 0.0 0.0016 17.5 0.0 1.2 1 1 0 1 1 1 1 ZIP Zinc transporter Cytomega_UL84 PF06284.6 ETO06185.1 - 0.56 8.5 2.4 0.88 7.9 1.7 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Nop14 PF04147.7 ETO06185.1 - 0.87 7.4 16.0 1.2 6.9 11.1 1.2 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.8 ETO06185.1 - 4.5 5.9 20.2 6.1 5.4 14.0 1.1 1 0 0 1 1 1 0 Paf1 Myc_N PF01056.13 ETO06185.1 - 6.1 5.9 7.6 3.7 6.6 4.0 1.5 2 0 0 2 2 2 0 Myc amino-terminal region DUF2457 PF10446.4 ETO06185.1 - 9.5 4.8 17.2 14 4.2 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) WD40 PF00400.27 ETO06187.1 - 4.1e-69 226.1 12.8 2.6e-13 49.2 0.8 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO06187.1 - 1.4e-11 43.2 4.7 0.018 13.1 0.1 5.2 2 1 2 5 5 5 5 Nucleoporin Nup120/160 Pentapeptide PF00805.17 ETO06187.1 - 7.2e-07 28.3 0.4 3.5e-06 26.1 0.2 2.1 1 1 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO06187.1 - 2.3e-05 24.1 0.1 4.9e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Cytochrom_D1 PF02239.11 ETO06187.1 - 0.00017 20.0 0.9 0.27 9.4 0.0 2.9 1 1 1 3 3 3 2 Cytochrome D1 heme domain Pentapeptide_3 PF13576.1 ETO06187.1 - 0.00018 21.3 0.7 0.00075 19.3 0.4 2.1 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) DUF1258 PF06869.7 ETO06187.1 - 0.0047 16.0 0.3 1.4 7.8 0.1 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF1258) DPPIV_N PF00930.16 ETO06187.1 - 0.011 14.3 0.0 0.51 8.8 0.0 2.7 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region SGL PF08450.7 ETO06187.1 - 0.046 13.0 0.2 0.52 9.6 0.0 2.7 1 1 1 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region NYD-SP28_assoc PF14775.1 ETO06187.1 - 0.048 13.3 0.4 11 5.7 0.0 4.1 5 0 0 5 5 5 0 Sperm tail C-terminal domain Str_synth PF03088.11 ETO06187.1 - 0.099 12.6 0.1 21 5.2 0.0 3.7 3 1 1 4 4 4 0 Strictosidine synthase PD40 PF07676.7 ETO06187.1 - 0.37 10.4 3.6 5.1 6.8 0.0 3.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Nop14 PF04147.7 ETO06188.1 - 1.6e-05 23.0 18.2 1.8e-05 22.8 12.6 1.1 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 ETO06188.1 - 7.3e-05 21.4 17.1 8.1e-05 21.3 11.9 1.2 1 0 0 1 1 1 1 Daxx Family BUD22 PF09073.5 ETO06188.1 - 0.00026 20.1 11.3 0.00032 19.9 7.8 1.2 1 0 0 1 1 1 1 BUD22 Drc1-Sld2 PF11719.3 ETO06188.1 - 0.0006 19.0 6.3 0.00066 18.8 4.4 1.3 1 0 0 1 1 1 1 DNA replication and checkpoint protein CDC45 PF02724.9 ETO06188.1 - 0.0016 16.5 16.1 0.002 16.2 11.1 1.1 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.7 ETO06188.1 - 0.0032 16.8 20.9 0.0041 16.4 14.5 1.1 1 0 0 1 1 1 1 SDA1 DUF1510 PF07423.6 ETO06188.1 - 0.0051 16.2 19.4 0.0074 15.6 13.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Ycf1 PF05758.7 ETO06188.1 - 0.012 13.3 6.8 0.015 13.0 4.7 1.1 1 0 0 1 1 1 0 Ycf1 DUF3895 PF13034.1 ETO06188.1 - 0.018 14.5 0.1 0.046 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3895) Pox_Ag35 PF03286.9 ETO06188.1 - 0.022 14.2 11.2 0.039 13.4 7.8 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Prothymosin PF03247.9 ETO06188.1 - 0.027 14.5 44.5 0.057 13.5 30.9 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family CENP-T PF15511.1 ETO06188.1 - 0.052 12.7 11.6 0.068 12.4 8.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TRAP_alpha PF03896.11 ETO06188.1 - 0.075 12.0 15.2 0.14 11.1 10.5 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2722 PF10846.3 ETO06188.1 - 0.081 11.9 9.5 0.11 11.5 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Jiv90 PF14901.1 ETO06188.1 - 0.094 12.7 0.6 7.1 6.6 0.0 2.5 1 1 1 2 2 2 0 Cleavage inducing molecular chaperone Hid1 PF12722.2 ETO06188.1 - 0.098 10.3 7.6 0.12 10.0 5.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DNA_pol_phi PF04931.8 ETO06188.1 - 0.12 10.1 29.6 0.15 9.8 20.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi TFIIA PF03153.8 ETO06188.1 - 0.13 12.1 23.4 0.025 14.5 13.6 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Mpp10 PF04006.7 ETO06188.1 - 0.26 9.6 24.1 0.35 9.1 16.7 1.1 1 0 0 1 1 1 0 Mpp10 protein Nop25 PF09805.4 ETO06188.1 - 0.28 11.2 19.1 0.58 10.2 13.2 1.5 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Prog_receptor PF02161.10 ETO06188.1 - 0.38 9.5 9.6 0.51 9.0 6.7 1.1 1 0 0 1 1 1 0 Progesterone receptor Zip PF02535.17 ETO06188.1 - 0.58 9.0 3.9 0.78 8.6 2.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2890 PF11081.3 ETO06188.1 - 0.61 10.1 18.3 0.93 9.5 12.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Tim54 PF11711.3 ETO06188.1 - 0.83 8.1 9.6 1.3 7.5 6.6 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Sporozoite_P67 PF05642.6 ETO06188.1 - 0.85 7.4 22.4 7.8 4.2 15.6 1.9 1 1 0 1 1 1 0 Sporozoite P67 surface antigen NARP1 PF12569.3 ETO06188.1 - 1 8.0 7.0 1.4 7.6 4.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Paf1 PF03985.8 ETO06188.1 - 1.2 7.7 24.7 2 7.0 17.2 1.2 1 0 0 1 1 1 0 Paf1 YqfQ PF14181.1 ETO06188.1 - 2.1 8.3 12.0 3.7 7.5 8.3 1.4 1 0 0 1 1 1 0 YqfQ-like protein RRN3 PF05327.6 ETO06188.1 - 2.5 6.0 14.2 3.2 5.7 9.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4637 PF15470.1 ETO06188.1 - 3 7.4 17.8 5.7 6.5 12.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DDHD PF02862.12 ETO06188.1 - 3 7.5 6.7 4.7 6.9 4.6 1.4 1 0 0 1 1 1 0 DDHD domain RNA_pol_3_Rpc31 PF11705.3 ETO06188.1 - 3.3 7.5 30.2 5.8 6.7 21.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Astro_capsid PF03115.9 ETO06188.1 - 3.3 5.8 6.8 3.5 5.7 4.7 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Cwf_Cwc_15 PF04889.7 ETO06188.1 - 4.2 7.0 21.9 7.5 6.1 15.2 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Peptidase_S64 PF08192.6 ETO06188.1 - 5.1 5.3 7.9 6.5 4.9 5.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 BTV_NS2 PF04514.7 ETO06188.1 - 7.6 5.3 14.0 15 4.3 9.7 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 TEX19 PF15553.1 ETO06188.1 - 9.6 6.0 10.9 17 5.2 7.5 1.4 1 0 0 1 1 1 0 Testis-expressed protein 19 DUF4302 PF14135.1 ETO06191.1 - 0.0028 17.0 0.1 0.0036 16.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4302) TfoX_C PF04994.8 ETO06191.1 - 0.13 12.2 0.4 2.4 8.1 0.0 2.2 2 0 0 2 2 2 0 TfoX C-terminal domain RNA_pol_Rpb5_C PF01191.14 ETO06192.1 - 7.6e-36 121.5 0.7 1.5e-35 120.6 0.5 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 ETO06192.1 - 2.4e-15 56.7 0.4 5.6e-15 55.5 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain ATP_bind_3 PF01171.15 ETO06192.1 - 0.00071 19.1 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 PP-loop family Sof1 PF04158.9 ETO06192.1 - 0.11 12.5 0.2 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 Sof1-like domain Pathogen_betaC1 PF09593.5 ETO06192.1 - 0.26 11.0 3.6 0.22 11.2 1.2 1.8 1 1 1 2 2 2 0 Beta-satellite pathogenicity beta C1 protein SAM_1 PF00536.25 ETO06193.1 - 4e-07 30.1 1.1 8.5e-07 29.0 0.7 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 ETO06193.1 - 0.0023 17.6 1.6 0.0073 16.0 0.1 2.5 3 0 0 3 3 3 1 Sterile alpha motif (SAM)/Pointed domain RGS PF00615.14 ETO06194.1 - 6.4e-05 23.0 0.2 8.5e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain WD40 PF00400.27 ETO06195.1 - 1e-31 107.5 2.1 4.4e-08 32.6 0.1 6.2 5 1 0 5 5 5 4 WD domain, G-beta repeat PD40 PF07676.7 ETO06195.1 - 0.0025 17.4 8.6 4.9 6.9 0.0 5.5 5 1 1 6 6 6 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO06195.1 - 0.0066 14.7 0.1 0.44 8.7 0.0 2.6 1 1 1 2 2 2 2 Cytochrome D1 heme domain DPPIV_N PF00930.16 ETO06195.1 - 0.01 14.4 0.7 0.42 9.1 0.0 3.1 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Proteasome_A_N PF10584.4 ETO06195.1 - 0.082 12.2 8.0 9.3 5.6 0.0 4.8 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature SGL PF08450.7 ETO06195.1 - 0.13 11.6 0.0 0.96 8.7 0.0 2.1 1 1 1 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region EBA-175_VI PF11556.3 ETO06196.1 - 0.033 14.2 3.4 0.046 13.8 2.3 1.3 1 0 0 1 1 1 0 Erythrocyte binding antigen 175 zf-C3HC4_2 PF13923.1 ETO06196.1 - 0.15 12.1 4.8 1.8 8.6 2.6 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO06196.1 - 0.92 9.3 7.2 12 5.8 5.0 2.4 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 ETO06196.1 - 3 7.5 6.4 2.4 7.9 0.1 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.27 ETO06197.1 - 4e-28 96.2 14.0 2e-07 30.6 0.7 6.1 5 1 1 6 6 6 6 WD domain, G-beta repeat Filament PF00038.16 ETO06198.1 - 0.012 15.0 4.3 0.012 15.0 3.0 3.4 2 1 1 3 3 3 0 Intermediate filament protein RadC PF04002.10 ETO06198.1 - 0.16 11.6 6.9 1.3 8.7 0.1 3.3 3 0 0 3 3 3 0 RadC-like JAB domain TAFH PF07531.9 ETO06198.1 - 7.1 6.3 12.3 0.083 12.5 0.5 3.2 3 0 0 3 3 3 0 NHR1 homology to TAF TetR_C_8 PF14278.1 ETO06200.1 - 0.22 11.9 1.4 0.88 9.9 0.2 2.0 1 1 1 2 2 2 0 Transcriptional regulator C-terminal region Peptidase_S15 PF02129.13 ETO06201.1 - 1.5e-18 67.1 2.8 5.3e-14 52.2 1.1 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Metallophos PF00149.23 ETO06202.1 - 3.4e-15 55.9 4.5 6.4e-15 55.0 3.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 ETO06202.1 - 1.2e-13 50.8 0.1 5.9e-13 48.6 0.0 2.2 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.2 ETO06202.1 - 5.9e-06 26.2 0.3 1.5e-05 24.8 0.2 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PhoD PF09423.5 ETO06202.1 - 1.8e-05 23.5 0.1 3.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 PhoD-like phosphatase DUF2431 PF10354.4 ETO06209.1 - 0.03 14.3 0.1 0.065 13.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) DUF939_C PF11728.3 ETO06210.1 - 1.4 8.7 8.5 0.29 10.9 0.1 2.6 3 0 0 3 3 3 0 DUF939 C-terminal domain PPR PF01535.15 ETO06212.1 - 1.1e-14 53.3 0.5 0.097 12.6 0.0 5.3 5 0 0 5 5 5 4 PPR repeat PPR_2 PF13041.1 ETO06212.1 - 9.9e-13 47.8 0.4 0.0013 18.6 0.0 4.6 3 1 2 5 5 5 5 PPR repeat family PPR_1 PF12854.2 ETO06212.1 - 3e-08 33.0 0.2 0.077 12.4 0.0 4.2 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.1 ETO06212.1 - 2.2e-06 27.5 0.0 3.7 8.0 0.0 4.8 4 0 0 4 4 4 2 Pentatricopeptide repeat domain RCC1 PF00415.13 ETO06213.1 - 1e-19 70.4 0.5 8e-10 38.7 0.0 4.6 5 1 1 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO06213.1 - 7.4e-08 31.8 2.3 3.9e-05 23.1 0.2 3.0 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat SET PF00856.23 ETO06214.1 - 2.2e-10 41.0 0.1 2.2e-10 41.0 0.1 1.8 2 0 0 2 2 2 1 SET domain CAP_GLY PF01302.20 ETO06215.1 - 1.1e-09 37.8 0.0 2.2e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain Ribosomal_L16 PF00252.13 ETO06217.1 - 5.3e-27 94.1 0.1 8.7e-27 93.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PAP_central PF04928.12 ETO06218.1 - 1.7e-06 27.0 0.3 2.4e-06 26.5 0.2 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain Ribosomal_S25 PF03297.10 ETO06218.1 - 0.2 11.7 3.5 0.23 11.5 2.0 1.4 1 1 0 1 1 1 0 S25 ribosomal protein CIAPIN1 PF05093.8 ETO06218.1 - 0.27 11.3 3.5 0.56 10.3 2.4 1.6 1 1 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis VPS28 PF03997.7 ETO06219.1 - 1.8e-46 158.1 0.5 1.2e-45 155.4 0.4 1.8 1 1 0 1 1 1 1 VPS28 protein DUF4485 PF14846.1 ETO06219.1 - 0.069 12.8 0.1 0.17 11.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) NdhM PF10664.4 ETO06219.1 - 0.072 13.0 0.1 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M DUF128 PF01995.11 ETO06219.1 - 0.093 11.6 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF128 GNT-I PF03071.10 ETO06219.1 - 0.094 11.2 0.0 0.14 10.6 0.0 1.3 1 0 0 1 1 1 0 GNT-I family Imm3 PF14425.1 ETO06219.1 - 0.1 12.5 1.9 0.84 9.6 0.1 2.5 2 2 0 2 2 2 0 Immunity protein Imm3 tRNA-synt_1d PF00750.14 ETO06220.1 - 1.8e-31 109.2 0.2 3.4e-26 91.9 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (R) Cystatin PF00031.16 ETO06221.1 - 0.56 10.3 3.8 0.62 10.2 0.2 2.3 1 1 2 3 3 3 0 Cystatin domain Peroxin-13_N PF04088.8 ETO06224.1 - 0.11 12.4 1.4 0.15 12.0 1.0 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region GOLD_2 PF13897.1 ETO06224.1 - 0.14 12.3 0.8 0.18 12.0 0.6 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking PH_4 PF15404.1 ETO06224.1 - 0.2 11.1 3.8 0.22 11.0 2.6 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain Pex14_N PF04695.8 ETO06224.1 - 1.1 9.3 6.5 1.3 9.0 4.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Secretin_N_2 PF07655.8 ETO06224.1 - 3.5 8.0 17.1 6.3 7.2 11.9 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain V-ATPase_H_N PF03224.9 ETO06226.1 - 2.1e-05 23.8 1.9 4e-05 22.9 1.3 1.4 1 0 0 1 1 1 1 V-ATPase subunit H Arm PF00514.18 ETO06226.1 - 0.00036 20.2 0.7 1.9 8.4 0.0 3.9 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat CDC27 PF09507.5 ETO06226.1 - 1 8.4 38.4 1.6 7.8 26.6 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MFS_2 PF13347.1 ETO06227.1 - 2.2e-07 29.6 7.1 4.9e-07 28.4 4.9 1.7 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.11 ETO06227.1 - 3.2e-07 29.4 4.3 4.2e-07 28.9 1.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.10 ETO06227.1 - 0.035 12.8 0.0 0.055 12.1 0.0 1.3 1 0 0 1 1 1 0 PUCC protein DUF3456 PF11938.3 ETO06228.1 - 7.3 6.5 9.7 9.7 6.1 0.4 3.0 1 1 1 3 3 3 0 TLR4 regulator and MIR-interacting MSAP DUF814 PF05670.8 ETO06229.1 - 1.2e-19 69.9 0.0 1.5e-18 66.4 0.0 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF814) DUF4407 PF14362.1 ETO06229.1 - 1.3 7.9 6.4 1.6 7.5 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RRM_1 PF00076.17 ETO06230.1 - 8.4e-18 63.7 0.1 2.6e-17 62.2 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO06230.1 - 5.8e-10 39.0 0.0 1.3e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO06230.1 - 8.2e-07 28.7 0.0 1.7e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VirB8 PF04335.8 ETO06231.1 - 0.056 13.0 0.1 0.076 12.5 0.1 1.1 1 0 0 1 1 1 0 VirB8 protein TPR_12 PF13424.1 ETO06232.1 - 1.4e-09 37.7 0.0 4.6e-07 29.6 0.0 2.4 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO06232.1 - 2.3e-07 30.3 1.7 0.0013 18.3 0.0 3.4 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.1 ETO06232.1 - 5.6e-07 28.8 1.6 0.0025 17.4 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO06232.1 - 0.00024 20.5 0.5 0.054 13.1 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETO06232.1 - 0.003 17.4 0.0 0.1 12.5 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO06232.1 - 0.011 15.6 0.7 4.1 7.5 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETO06232.1 - 0.028 14.2 0.0 0.12 12.2 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Fer4_12 PF13353.1 ETO06232.1 - 0.028 14.5 0.6 0.12 12.4 0.0 2.3 2 1 0 2 2 2 0 4Fe-4S single cluster domain RNA_pol_A_bac PF01000.21 ETO06232.1 - 2.9 8.0 5.7 11 6.2 0.5 3.3 2 2 2 4 4 4 0 RNA polymerase Rpb3/RpoA insert domain SAM_1 PF00536.25 ETO06233.1 - 0.0065 16.6 1.4 13 6.0 0.0 4.1 4 0 0 4 4 4 1 SAM domain (Sterile alpha motif) DUF2139 PF09910.4 ETO06233.1 - 0.086 11.8 0.0 2.6 6.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2139) MttA_Hcf106 PF02416.11 ETO06233.1 - 1 8.5 3.5 14 4.8 0.0 2.9 2 0 0 2 2 2 0 mttA/Hcf106 family TINF2_N PF14973.1 ETO06233.1 - 3 7.9 7.7 0.52 10.4 0.9 2.9 2 1 2 4 4 4 0 TERF1-interacting nuclear factor 2 N-terminus LRR_6 PF13516.1 ETO06234.1 - 8e-10 37.7 20.6 0.044 13.8 0.0 6.9 7 1 0 7 7 7 4 Leucine Rich repeat LRR_1 PF00560.28 ETO06234.1 - 3.2e-05 23.3 12.9 7.3 7.0 0.0 7.4 8 0 0 8 8 8 3 Leucine Rich Repeat LRR_4 PF12799.2 ETO06234.1 - 0.0018 17.8 15.4 0.52 9.9 0.0 5.9 5 2 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO06234.1 - 0.71 9.6 18.1 25 4.7 0.0 6.4 4 3 0 4 4 4 0 Leucine rich repeat SCHIP-1 PF10148.4 ETO06237.1 - 0.039 13.3 0.9 0.056 12.8 0.2 1.5 2 0 0 2 2 2 0 Schwannomin-interacting protein 1 Peroxin-22 PF12827.2 ETO06237.1 - 0.056 13.1 0.1 0.14 11.8 0.1 1.7 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family Spore_III_AB PF09548.5 ETO06237.1 - 0.072 12.8 0.3 0.25 11.0 0.1 1.9 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) ARA70 PF12489.3 ETO06237.1 - 0.11 12.4 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 Nuclear coactivator AAA_35 PF14516.1 ETO06238.1 - 0.0095 14.6 0.3 0.013 14.1 0.2 1.1 1 0 0 1 1 1 1 AAA-like domain ESCRT-II PF05871.7 ETO06238.1 - 0.088 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 ESCRT-II complex subunit WD40 PF00400.27 ETO06239.1 - 2.6e-23 80.9 10.0 4.1e-09 35.9 0.2 4.8 4 1 1 5 5 5 4 WD domain, G-beta repeat Nop14 PF04147.7 ETO06241.1 - 0.0016 16.5 27.3 0.002 16.1 18.9 1.1 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 ETO06241.1 - 0.0025 16.3 18.3 0.0026 16.3 12.7 1.1 1 0 0 1 1 1 1 Daxx Family SDA1 PF05285.7 ETO06241.1 - 0.0048 16.2 30.0 0.0057 15.9 20.8 1.1 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.9 ETO06241.1 - 0.078 11.0 17.6 0.11 10.5 12.2 1.3 1 0 0 1 1 1 0 CDC45-like protein HABP4_PAI-RBP1 PF04774.10 ETO06241.1 - 1 9.9 22.0 1.8 9.1 14.8 1.8 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family CENP-T PF15511.1 ETO06241.1 - 1.2 8.2 14.4 1.5 7.9 10.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T FAM60A PF15396.1 ETO06241.1 - 2.3 7.9 8.0 4.4 6.9 5.5 1.5 1 0 0 1 1 1 0 Protein Family FAM60A Corona_nucleoca PF00937.13 ETO06241.1 - 4.9 5.9 10.4 7.1 5.4 7.2 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein SpoIIIAH PF12685.2 ETO06241.1 - 5.3 6.4 20.3 6.5 6.1 14.1 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein SAPS PF04499.10 ETO06241.1 - 8.8 4.8 11.9 10 4.6 8.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein WD40 PF00400.27 ETO06242.1 - 1.2e-57 189.8 26.8 2.3e-10 39.9 0.9 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO06242.1 - 9e-07 27.3 6.6 0.058 11.5 0.0 5.5 1 1 2 5 5 5 5 Nucleoporin Nup120/160 DUF2700 PF10912.3 ETO06242.1 - 0.032 14.2 0.4 0.032 14.2 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2700) DUF1670 PF07900.6 ETO06243.1 - 0.022 14.0 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1670) 2OG-FeII_Oxy_3 PF13640.1 ETO06243.1 - 0.042 14.3 0.0 0.092 13.2 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily TetR_C_8 PF14278.1 ETO06243.1 - 0.058 13.7 1.1 0.14 12.5 0.8 1.8 1 0 0 1 1 1 0 Transcriptional regulator C-terminal region AAA_17 PF13207.1 ETO06244.1 - 6.9e-05 23.6 0.9 0.00037 21.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETO06244.1 - 0.00012 22.3 3.7 0.00066 19.9 0.2 2.8 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 ETO06244.1 - 0.0014 18.7 0.0 0.0028 17.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 ETO06244.1 - 0.0032 17.1 0.0 0.0051 16.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain UPF0079 PF02367.12 ETO06244.1 - 0.0042 16.7 0.0 0.0078 15.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 PRK PF00485.13 ETO06244.1 - 0.0055 16.2 0.0 0.0093 15.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.22 ETO06244.1 - 0.02 15.1 3.6 0.1 12.8 2.3 2.3 1 1 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 ETO06244.1 - 0.022 14.9 1.7 0.21 11.7 0.0 2.6 2 1 0 2 2 2 0 RNA helicase DAP3 PF10236.4 ETO06244.1 - 0.023 13.6 0.9 0.051 12.5 0.2 1.7 1 1 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_33 PF13671.1 ETO06244.1 - 0.026 14.3 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 ETO06244.1 - 0.031 13.9 2.8 0.069 12.8 1.9 1.8 1 1 0 1 1 1 0 Archaeal ATPase DUF258 PF03193.11 ETO06244.1 - 0.038 13.1 0.0 0.068 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ATP_bind_2 PF03668.10 ETO06244.1 - 0.051 12.6 0.0 0.078 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop ATPase protein family Zeta_toxin PF06414.7 ETO06244.1 - 0.055 12.5 0.0 0.086 11.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.1 ETO06244.1 - 0.075 12.5 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RVT_1 PF00078.22 ETO06245.1 - 1.7e-20 73.2 0.0 4e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Prefoldin PF02996.12 ETO06245.1 - 0.029 13.9 0.5 0.13 11.9 0.3 2.1 2 0 0 2 2 2 0 Prefoldin subunit WD40 PF00400.27 ETO06246.1 - 1.7e-47 157.6 13.5 4e-12 45.5 0.1 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat Pentapeptide PF00805.17 ETO06246.1 - 0.00047 19.3 0.3 0.00098 18.3 0.2 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Nbas_N PF15492.1 ETO06246.1 - 0.0032 16.6 0.8 3.3 6.7 0.0 3.5 1 1 2 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Pentapeptide_3 PF13576.1 ETO06246.1 - 0.0046 16.8 1.9 0.015 15.1 1.3 2.0 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.1 ETO06246.1 - 0.0095 15.7 0.4 0.026 14.3 0.3 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) PD40 PF07676.7 ETO06246.1 - 0.048 13.3 1.5 7.7 6.2 0.0 4.0 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF3763 PF12592.3 ETO06246.1 - 0.16 11.6 2.7 2.3 7.9 0.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3763) Pro_isomerase PF00160.16 ETO06247.1 - 2.9e-46 157.5 0.2 3.3e-46 157.3 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-A20 PF01754.11 ETO06247.1 - 7 6.3 7.9 24 4.6 1.7 2.6 2 0 0 2 2 2 0 A20-like zinc finger SR-25 PF10500.4 ETO06248.1 - 0.07 12.5 9.7 0.092 12.2 6.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Trypan_PARP PF05887.6 ETO06248.1 - 0.072 12.9 2.0 0.09 12.5 1.4 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Rtf2 PF04641.7 ETO06248.1 - 0.61 9.2 8.1 0.78 8.8 5.6 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger GAGA_bind PF06217.7 ETO06248.1 - 1.4 8.7 6.1 1.8 8.4 4.2 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Vfa1 PF08432.5 ETO06248.1 - 1.9 8.4 10.8 2.5 8.0 7.5 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Dsh_C PF12316.3 ETO06248.1 - 7.8 6.5 6.9 9.4 6.2 4.8 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal TFIIF_alpha PF05793.7 ETO06248.1 - 8.8 4.5 20.8 10 4.3 14.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) eIF-3c_N PF05470.7 ETO06248.1 - 9.8 4.1 10.1 12 3.8 7.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF1664 PF07889.7 ETO06250.1 - 1.1 9.0 15.5 2 8.1 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ACCA PF03255.9 ETO06250.1 - 1.6 8.2 16.4 0.14 11.7 0.4 3.7 2 1 1 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF489 PF04356.7 ETO06250.1 - 8.9 5.8 11.7 19 4.7 0.1 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF489) Tctex-1 PF03645.8 ETO06251.1 - 1.2e-05 25.0 0.4 1.2e-05 25.0 0.2 2.4 2 1 0 2 2 2 1 Tctex-1 family CAP_GLY PF01302.20 ETO06252.1 - 1.2e-20 73.0 0.6 2.4e-20 72.0 0.4 1.5 1 0 0 1 1 1 1 CAP-Gly domain DivIC PF04977.10 ETO06252.1 - 0.22 11.0 32.6 0.12 11.9 3.9 4.3 2 1 2 4 4 4 0 Septum formation initiator DUF111 PF01969.12 ETO06252.1 - 0.53 9.0 2.7 0.83 8.3 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF111 V_ATPase_I PF01496.14 ETO06252.1 - 0.61 7.8 12.4 1.1 7.0 8.6 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.6 ETO06252.1 - 1.4 8.8 17.5 0.54 10.1 0.1 4.3 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.16 ETO06252.1 - 2.7 8.0 23.5 0.23 11.4 4.1 4.4 2 1 2 4 4 4 0 bZIP transcription factor DUF2937 PF11157.3 ETO06252.1 - 2.7 7.2 8.4 0.79 9.0 2.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) IncA PF04156.9 ETO06252.1 - 2.8 7.4 33.2 1.5 8.3 11.5 2.3 1 1 1 2 2 2 0 IncA protein Spc7 PF08317.6 ETO06252.1 - 4 6.0 28.3 1.2 7.7 15.6 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF2968 PF11180.3 ETO06252.1 - 6.1 6.1 27.5 0.77 9.1 4.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) CENP-Q PF13094.1 ETO06252.1 - 7 6.6 26.1 6.5 6.7 13.9 2.7 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Herpes_BLRF2 PF05812.7 ETO06252.1 - 9.3 6.0 18.2 18 5.1 9.7 2.7 1 1 2 3 3 3 0 Herpesvirus BLRF2 protein DUF4406 PF14359.1 ETO06253.1 - 0.016 15.2 0.4 0.024 14.6 0.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4406) IL22 PF14565.1 ETO06253.1 - 0.75 9.8 5.3 1.2 9.2 3.6 1.3 1 0 0 1 1 1 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor DUF4337 PF14235.1 ETO06253.1 - 4 7.2 8.6 7.1 6.4 6.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF106 PF01956.11 ETO06253.1 - 4.4 6.8 8.0 4.9 6.6 5.5 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 Peptidase_S49_N PF08496.5 ETO06253.1 - 4.6 7.0 13.7 6.4 6.5 9.5 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Radial_spoke_3 PF06098.6 ETO06253.1 - 5 6.0 9.6 5.6 5.8 6.6 1.2 1 0 0 1 1 1 0 Radial spoke protein 3 NARP1 PF12569.3 ETO06253.1 - 5.8 5.5 11.8 5.7 5.5 8.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SAP18 PF06487.7 ETO06255.1 - 0.085 12.6 1.2 9.9 5.9 0.0 2.3 1 1 1 2 2 2 0 Sin3 associated polypeptide p18 (SAP18) Arch_flagellin PF01917.11 ETO06255.1 - 0.089 12.3 0.6 0.12 12.0 0.4 1.2 1 0 0 1 1 1 0 Archaebacterial flagellin Rpn3_C PF08375.6 ETO06255.1 - 0.12 12.7 0.7 0.12 12.7 0.5 2.3 2 0 0 2 2 2 0 Proteasome regulatory subunit C-terminal Pkinase PF00069.20 ETO06257.1 - 1.3e-06 27.7 0.0 1.3e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Peptidase_C48 PF02902.14 ETO06257.1 - 0.0071 15.9 0.2 0.017 14.7 0.1 1.6 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MT-A70 PF05063.9 ETO06258.1 - 2e-39 134.9 0.0 3.2e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 MT-A70 Methyltransf_26 PF13659.1 ETO06258.1 - 0.041 13.9 0.0 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain CDC45 PF02724.9 ETO06258.1 - 3.4 5.5 8.7 4.5 5.2 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.27 ETO06259.1 - 4e-26 89.9 8.3 2.8e-11 42.8 0.1 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO06259.1 - 9.6e-05 20.7 0.8 0.46 8.5 0.0 2.9 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO06259.1 - 0.0055 15.5 2.1 0.78 8.4 0.4 2.8 1 1 1 2 2 2 1 Nup133 N terminal like IgaA PF07095.6 ETO06259.1 - 0.028 12.1 0.0 0.038 11.7 0.0 1.1 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA PRKCSH-like PF12999.2 ETO06259.1 - 0.47 10.0 4.8 1 8.8 2.5 2.0 2 0 0 2 2 2 0 Glucosidase II beta subunit-like WD40 PF00400.27 ETO06260.1 - 1.9e-10 40.1 0.2 5.2e-09 35.6 0.0 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF1921 PF09081.5 ETO06260.1 - 0.12 12.3 0.1 6.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1921) DUF3915 PF13054.1 ETO06260.1 - 0.13 12.2 0.4 0.16 11.8 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3915) Secretin_N_2 PF07655.8 ETO06261.1 - 0.2 12.0 7.1 0.38 11.1 4.9 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Apis_Csd PF11671.3 ETO06261.1 - 0.42 10.4 7.9 0.58 9.9 5.5 1.2 1 0 0 1 1 1 0 Complementary sex determiner protein Thr_synth_N PF14821.1 ETO06262.1 - 1.3e-18 66.7 0.0 1.9e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Threonine synthase N terminus CBFD_NFYB_HMF PF00808.18 ETO06262.1 - 0.15 12.1 0.0 0.72 9.9 0.0 1.9 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone NifW PF03206.9 ETO06263.1 - 0.1 12.6 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 Nitrogen fixation protein NifW Med8 PF10232.4 ETO06264.1 - 0.021 14.3 1.0 0.038 13.5 0.7 1.4 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 GSH_synthase PF03199.10 ETO06264.1 - 0.082 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic glutathione synthase Nbs1_C PF08599.5 ETO06264.1 - 0.23 11.3 0.0 0.23 11.3 0.0 4.2 4 0 0 4 4 4 0 DNA damage repair protein Nbs1 Sina PF03145.11 ETO06265.1 - 0.00056 19.6 0.4 0.00068 19.3 0.3 1.3 1 0 0 1 1 1 1 Seven in absentia protein family DUF4200 PF13863.1 ETO06265.1 - 0.0042 17.0 2.5 0.0095 15.8 1.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) Ly49 PF08391.5 ETO06265.1 - 0.032 14.3 1.8 0.032 14.3 1.2 1.9 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region YgaB PF14182.1 ETO06265.1 - 0.043 14.0 1.9 0.043 14.0 1.3 1.7 2 0 0 2 2 2 0 YgaB-like protein ARA70 PF12489.3 ETO06265.1 - 0.1 12.5 0.6 0.19 11.7 0.4 1.7 1 1 0 1 1 1 0 Nuclear coactivator Methyltransf_2 PF00891.13 ETO06266.1 - 0.022 13.9 0.2 0.039 13.1 0.1 1.5 1 1 0 1 1 1 0 O-methyltransferase F-box-like PF12937.2 ETO06268.1 - 0.00024 20.7 0.1 0.00049 19.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like Chordopox_G2 PF05796.7 ETO06268.1 - 0.0077 15.3 1.7 0.015 14.4 1.2 1.4 1 0 0 1 1 1 1 Chordopoxvirus protein G2 Pentapeptide PF00805.17 ETO06268.1 - 0.038 13.2 0.1 0.069 12.4 0.0 1.5 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) F-box PF00646.28 ETO06268.1 - 0.16 11.6 1.5 0.25 11.0 0.1 2.0 2 0 0 2 2 2 0 F-box domain G-patch PF01585.18 ETO06269.1 - 1.7e-08 34.1 6.4 3.5e-08 33.1 4.4 1.4 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 ETO06269.1 - 5.1e-08 32.6 0.0 9.6e-07 28.5 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO06269.1 - 0.0031 17.0 0.2 0.0078 15.8 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 ETO06269.1 - 0.012 15.3 16.4 0.017 14.8 11.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) G-patch_2 PF12656.2 ETO06269.1 - 0.043 13.6 0.1 0.043 13.6 0.1 2.1 2 0 0 2 2 2 0 DExH-box splicing factor binding site RRM_6 PF14259.1 ETO06269.1 - 0.062 13.2 0.1 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SBP_bac_5 PF00496.17 ETO06269.1 - 0.12 11.1 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle DUF4661 PF15576.1 ETO06269.1 - 0.8 9.2 6.0 1.1 8.8 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Prok-RING_1 PF14446.1 ETO06270.1 - 0.0016 18.1 3.5 0.0016 18.1 2.4 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-NF-X1 PF01422.12 ETO06270.1 - 0.018 14.9 16.8 0.018 14.9 11.6 3.3 3 0 0 3 3 3 0 NF-X1 type zinc finger C1_1 PF00130.17 ETO06270.1 - 0.17 11.6 11.9 0.079 12.6 4.8 2.9 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SH2 PF00017.19 ETO06271.1 - 1.6e-08 34.2 0.0 4.1e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 SH2 domain Bromodomain PF00439.20 ETO06273.1 - 2e-12 46.8 1.7 7.5e-12 45.0 0.0 2.5 1 1 2 3 3 3 1 Bromodomain PP_M1 PF03012.9 ETO06274.1 - 0.0005 19.5 9.0 0.00078 18.8 6.3 1.3 1 0 0 1 1 1 1 Phosphoprotein U79_P34 PF03064.11 ETO06274.1 - 0.2 11.1 18.2 0.34 10.4 12.6 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CDC45 PF02724.9 ETO06274.1 - 1 7.2 19.1 1.3 6.9 13.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2201_N PF13203.1 ETO06274.1 - 3.5 6.7 11.8 4.8 6.2 8.2 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Zip PF02535.17 ETO06274.1 - 5.2 5.9 5.0 6.4 5.6 3.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.11 ETO06274.1 - 6.9 6.4 9.8 11 5.8 6.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.7 ETO06274.1 - 8.9 6.1 16.5 13 5.5 11.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 WD40 PF00400.27 ETO06275.1 - 1.9e-46 154.3 12.1 5.1e-13 48.3 0.0 5.0 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 ETO06275.1 - 1.2e-07 31.5 0.2 6.3e-05 22.7 0.1 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 ETO06275.1 - 3.5e-05 23.0 0.4 0.99 8.4 0.0 3.1 1 1 2 3 3 3 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 ETO06275.1 - 0.00011 21.7 4.2 1.1 9.0 0.1 3.4 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO06275.1 - 0.0002 19.6 1.3 0.061 11.4 0.1 3.3 1 1 2 4 4 4 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO06275.1 - 0.00025 19.9 5.6 0.32 9.6 0.0 3.9 1 1 3 4 4 4 2 Nup133 N terminal like PQQ_2 PF13360.1 ETO06275.1 - 0.0084 15.5 0.0 0.02 14.3 0.0 1.6 1 1 0 1 1 1 1 PQQ-like domain Hira PF07569.6 ETO06275.1 - 0.011 14.9 0.5 9.1 5.4 0.0 3.3 1 1 3 4 4 4 0 TUP1-like enhancer of split Ricin_B_lectin PF00652.17 ETO06275.1 - 0.013 15.5 2.2 0.097 12.7 0.1 2.4 1 1 1 3 3 3 0 Ricin-type beta-trefoil lectin domain Cytochrom_D1 PF02239.11 ETO06275.1 - 0.051 11.8 0.0 3 6.0 0.0 1.8 1 1 0 1 1 1 0 Cytochrome D1 heme domain B_lectin PF01453.19 ETO06275.1 - 0.085 12.7 0.0 0.3 10.9 0.0 1.9 1 1 1 2 2 2 0 D-mannose binding lectin Proteasome_A_N PF10584.4 ETO06275.1 - 1.1 8.6 7.5 32 3.9 0.2 3.4 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Menin PF05053.8 ETO06276.1 - 0.053 11.7 3.3 0.08 11.0 2.3 1.3 1 0 0 1 1 1 0 Menin Fer4_18 PF13746.1 ETO06276.1 - 0.21 12.0 3.8 0.13 12.6 0.7 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain WD40 PF00400.27 ETO06277.1 - 4.6e-47 156.2 5.4 2.2e-13 49.5 0.1 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat PD40 PF07676.7 ETO06277.1 - 0.00042 19.8 1.1 4.7 6.9 0.0 4.0 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 ETO06277.1 - 0.0073 15.4 0.1 0.28 10.2 0.0 2.6 1 1 2 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 ETO06277.1 - 0.014 14.7 5.0 13 5.1 0.0 4.9 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Cytochrom_D1 PF02239.11 ETO06277.1 - 0.021 13.1 0.0 1.2 7.3 0.0 2.0 1 1 1 2 2 2 0 Cytochrome D1 heme domain Nup160 PF11715.3 ETO06277.1 - 0.052 11.6 0.3 1.3 7.0 0.2 2.3 1 1 0 1 1 1 0 Nucleoporin Nup120/160 TFIIIC_delta PF12657.2 ETO06277.1 - 0.055 13.1 0.2 0.11 12.1 0.2 1.5 1 1 0 1 1 1 0 Transcription factor IIIC subunit delta N-term AcetylCoA_hyd_C PF13336.1 ETO06277.1 - 0.09 12.4 0.0 11 5.6 0.0 2.6 2 1 1 3 3 3 0 Acetyl-CoA hydrolase/transferase C-terminal domain WD40 PF00400.27 ETO06278.1 - 3.9e-24 83.5 11.5 4.2e-09 35.9 0.0 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO06278.1 - 0.006 14.7 1.3 2.6 6.0 0.2 2.9 2 1 1 3 3 3 2 Nucleoporin Nup120/160 DUF285 PF03382.9 ETO06278.1 - 0.093 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 Aldo_ket_red PF00248.16 ETO06279.1 - 2.2e-27 95.6 0.4 2.9e-27 95.2 0.3 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pex14_N PF04695.8 ETO06279.1 - 0.09 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Phage_int_SAM_5 PF13102.1 ETO06280.1 - 0.13 12.2 1.7 0.17 11.8 0.2 1.8 2 0 0 2 2 2 0 Phage integrase SAM-like domain PI3_PI4_kinase PF00454.22 ETO06281.1 - 2.3e-36 125.4 0.6 6.1e-36 124.0 0.4 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 ETO06281.1 - 2.1e-28 98.7 3.1 4.3e-28 97.7 2.2 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) AAA_16 PF13191.1 ETO06282.1 - 2.5e-07 30.8 0.0 3.2e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain DAP3 PF10236.4 ETO06282.1 - 0.012 14.5 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NB-ARC PF00931.17 ETO06282.1 - 0.019 13.8 0.0 0.025 13.4 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain Arch_ATPase PF01637.13 ETO06282.1 - 0.019 14.6 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_22 PF13401.1 ETO06282.1 - 0.039 14.0 0.0 0.08 13.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain PH PF00169.24 ETO06283.1 - 4.1e-06 26.9 3.1 1.2e-05 25.4 2.1 1.9 1 0 0 1 1 1 1 PH domain AAA_22 PF13401.1 ETO06283.1 - 0.0064 16.6 0.8 0.019 15.1 0.1 2.2 2 0 0 2 2 2 1 AAA domain PH_8 PF15409.1 ETO06283.1 - 0.0086 16.1 0.3 0.024 14.6 0.2 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Tudor-knot PF11717.3 ETO06284.1 - 3.4e-13 49.0 5.2 4.5e-13 48.6 2.8 1.9 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain DUF1325 PF07039.6 ETO06284.1 - 0.00045 19.8 1.0 0.012 15.1 0.1 2.9 2 1 1 3 3 3 1 SGF29 tudor-like domain Chromo PF00385.19 ETO06284.1 - 0.0019 17.8 3.7 0.0037 16.8 2.2 1.8 1 1 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tox-GHH2 PF15635.1 ETO06284.1 - 0.22 11.9 3.8 0.3 11.4 2.0 1.8 1 1 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin 2 Macoilin PF09726.4 ETO06284.1 - 1 7.5 14.9 1.3 7.2 10.3 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF4110 PF13422.1 ETO06284.1 - 7.3 6.5 11.0 0.54 10.1 3.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4110) RuvA_C PF07499.8 ETO06285.1 - 0.027 14.6 0.1 0.047 13.8 0.1 1.3 1 0 0 1 1 1 0 RuvA, C-terminal domain Guanylate_cyc PF00211.15 ETO06286.1 - 3.9e-19 68.7 0.0 1.6e-11 43.8 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain SET PF00856.23 ETO06287.1 - 1.3e-12 48.3 0.1 2.9e-12 47.1 0.1 1.7 1 1 0 1 1 1 1 SET domain Bromodomain PF00439.20 ETO06288.1 - 3.1e-13 49.4 0.9 6.3e-13 48.4 0.6 1.5 1 0 0 1 1 1 1 Bromodomain UPF0121 PF03661.8 ETO06288.1 - 0.016 14.4 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0121) Pex24p PF06398.6 ETO06288.1 - 0.087 11.6 0.0 0.087 11.6 0.0 2.1 2 1 0 2 2 2 0 Integral peroxisomal membrane peroxin Insulin PF00049.13 ETO06288.1 - 0.55 11.0 3.9 29 5.5 0.0 2.6 2 0 0 2 2 2 0 Insulin/IGF/Relaxin family DUF2215 PF10225.4 ETO06288.1 - 2.6 7.4 4.7 0.85 9.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) p450 PF00067.17 ETO06289.1 - 6.3e-75 252.4 2.1 8e-75 252.1 1.4 1.0 1 0 0 1 1 1 1 Cytochrome P450 HIT PF01230.18 ETO06290.1 - 3.7e-08 33.8 0.1 9.1e-08 32.5 0.0 1.7 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.3 ETO06290.1 - 0.0041 17.3 0.0 0.0066 16.6 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Ribosomal_S4Pg PF11993.3 ETO06291.1 - 0.011 15.5 2.2 0.017 14.9 1.5 1.3 1 0 0 1 1 1 0 Ribosomal S4P (gammaproteobacterial) Cir_N PF10197.4 ETO06291.1 - 0.035 14.1 1.4 0.035 14.1 0.9 2.9 4 0 0 4 4 4 0 N-terminal domain of CBF1 interacting co-repressor CIR NESP55 PF06390.7 ETO06292.1 - 0.00077 18.9 0.8 0.00077 18.9 0.6 1.6 2 0 0 2 2 2 1 Neuroendocrine-specific golgi protein P55 (NESP55) SAM_2 PF07647.12 ETO06292.1 - 0.0044 16.8 0.0 0.08 12.7 0.0 2.5 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) WD40 PF00400.27 ETO06294.1 - 8.9e-27 91.9 8.8 5.3e-11 41.9 0.2 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO06294.1 - 1.9e-09 36.2 0.6 1.1e-07 30.4 0.1 2.0 1 1 0 2 2 2 1 Nucleoporin Nup120/160 POLO_box PF00659.13 ETO06294.1 - 0.01 15.7 4.6 0.63 10.0 0.8 2.6 2 0 0 2 2 2 0 POLO box duplicated region Prominin PF05478.6 ETO06294.1 - 0.015 12.8 4.9 0.019 12.5 3.4 1.1 1 0 0 1 1 1 0 Prominin DUF2924 PF11149.3 ETO06294.1 - 0.017 15.1 0.6 0.051 13.5 0.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2924) Laminin_II PF06009.7 ETO06294.1 - 0.021 14.5 8.5 0.03 14.0 5.9 1.2 1 0 0 1 1 1 0 Laminin Domain II FTO_NTD PF12933.2 ETO06294.1 - 0.029 13.4 0.8 0.04 13.0 0.5 1.2 1 0 0 1 1 1 0 FTO catalytic domain RSV_NS2 PF03113.9 ETO06294.1 - 0.043 13.7 0.2 0.066 13.1 0.1 1.3 1 0 0 1 1 1 0 Respiratory synctial virus non-structural protein NS2 Viral_env_E26 PF11050.3 ETO06294.1 - 0.067 12.3 5.4 0.098 11.8 3.8 1.2 1 0 0 1 1 1 0 Virus envelope protein E26 LAM_C PF12544.3 ETO06294.1 - 0.14 12.2 1.1 0.17 11.9 0.1 1.7 2 0 0 2 2 2 0 Lysine-2,3-aminomutase DUF413 PF04219.7 ETO06294.1 - 0.15 11.8 1.5 0.28 10.9 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF DUF2408 PF10303.4 ETO06294.1 - 0.18 11.8 9.3 0.27 11.3 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) V-ATPase_G PF03179.10 ETO06294.1 - 0.19 12.0 11.3 0.36 11.1 7.8 1.5 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit V_ATPase_I PF01496.14 ETO06294.1 - 0.65 7.7 5.2 0.71 7.6 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PhoU PF01895.14 ETO06294.1 - 2.8 8.4 8.4 16 6.0 1.9 2.3 1 1 1 2 2 2 0 PhoU domain Phlebovirus_NSM PF07246.6 ETO06294.1 - 3.8 6.5 10.3 6.2 5.8 7.2 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Atg14 PF10186.4 ETO06294.1 - 6.3 5.6 14.6 8.2 5.2 10.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Kinetocho_Slk19 PF12709.2 ETO06294.1 - 9.9 6.3 15.5 2.5 8.2 6.9 2.2 1 1 1 2 2 2 0 Central kinetochore-associated zf-TRAF PF02176.13 ETO06295.1 - 6.7e-05 23.1 1.3 6.7e-05 23.1 0.9 3.4 3 0 0 3 3 3 2 TRAF-type zinc finger Pkinase PF00069.20 ETO06296.1 - 1.3e-51 175.2 0.0 2.9e-51 174.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO06296.1 - 1.3e-18 67.0 0.0 3.5e-18 65.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.24 ETO06296.1 - 2.2e-14 53.0 0.0 1.4e-09 37.6 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain APH PF01636.18 ETO06296.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family MRP-L47 PF06984.8 ETO06297.1 - 0.062 13.2 0.2 0.19 11.6 0.1 1.8 1 0 0 1 1 1 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF843 PF05814.6 ETO06297.1 - 1.3 8.8 7.7 4.8 7.0 0.3 2.7 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) Myotub-related PF06602.9 ETO06298.1 - 8.1e-29 100.4 0.1 1e-28 100.1 0.1 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain OTCace_N PF02729.16 ETO06299.1 - 4.7e-39 133.2 0.0 3.1e-38 130.6 0.0 2.1 1 1 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 ETO06299.1 - 1.4e-32 112.7 0.1 4.3e-32 111.1 0.1 1.8 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ETRAMP PF09716.5 ETO06300.1 - 2.1 8.3 7.1 13 5.7 3.1 3.3 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF4344 PF14247.1 ETO06302.1 - 0.035 13.7 2.9 0.045 13.4 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4344) DRY_EERY PF09750.4 ETO06302.1 - 0.1 12.7 13.1 0.3 11.1 0.3 2.0 1 1 1 2 2 2 0 Alternative splicing regulator DUF2314 PF10077.4 ETO06304.1 - 0.0038 17.2 0.1 0.007 16.4 0.1 1.4 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2314) Flavi_M PF01004.14 ETO06304.1 - 0.093 12.1 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M Rep_1 PF01446.12 ETO06304.1 - 0.098 11.9 0.1 0.12 11.6 0.1 1.1 1 0 0 1 1 1 0 Replication protein Secretin_N_2 PF07655.8 ETO06306.1 - 0.17 12.3 12.1 0.38 11.1 8.4 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain Apis_Csd PF11671.3 ETO06306.1 - 1.8 8.3 14.2 3.2 7.5 9.9 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein Wbp11 PF09429.5 ETO06307.1 - 0.38 10.7 8.5 0.72 9.8 5.9 1.5 1 1 0 1 1 1 0 WW domain binding protein 11 HD_3 PF13023.1 ETO06308.1 - 0.0042 16.8 0.7 0.0042 16.8 0.5 1.6 2 0 0 2 2 2 1 HD domain CLAMP PF14769.1 ETO06308.1 - 0.011 15.8 1.4 0.024 14.7 1.0 1.6 1 0 0 1 1 1 0 Flagellar C1a complex subunit C1a-32 Sfi1 PF08457.5 ETO06308.1 - 0.19 10.1 9.5 0.32 9.3 6.5 1.5 1 1 0 1 1 1 0 Sfi1 spindle body protein Reo_sigmaC PF04582.7 ETO06310.1 - 0.0004 19.6 2.9 0.0004 19.6 2.0 3.0 1 1 2 3 3 3 2 Reovirus sigma C capsid protein Filament PF00038.16 ETO06310.1 - 0.0088 15.5 57.3 0.01 15.3 7.6 3.3 1 1 2 3 3 3 2 Intermediate filament protein DUF4380 PF14315.1 ETO06310.1 - 0.013 14.7 2.4 0.068 12.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4380) NPV_P10 PF05531.7 ETO06310.1 - 0.029 14.6 32.0 0.34 11.1 2.4 5.0 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein ADIP PF11559.3 ETO06310.1 - 0.12 12.2 67.2 0.27 11.1 11.1 4.2 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding DASH_Dam1 PF08653.5 ETO06310.1 - 0.4 10.4 8.5 4.5 7.1 0.1 4.6 3 1 1 4 4 4 0 DASH complex subunit Dam1 IncA PF04156.9 ETO06310.1 - 0.5 9.9 66.8 0.5 9.9 12.9 4.1 1 1 4 5 5 5 0 IncA protein TPR_MLP1_2 PF07926.7 ETO06310.1 - 0.93 9.2 63.3 0.35 10.5 9.5 3.8 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein LPP PF04728.8 ETO06310.1 - 1.3 8.8 17.6 0.52 10.1 0.4 4.9 5 0 0 5 5 5 0 Lipoprotein leucine-zipper NAAA-beta PF15508.1 ETO06310.1 - 2.8 8.3 9.3 3.6 8.0 0.2 4.3 1 1 2 4 4 4 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF3584 PF12128.3 ETO06310.1 - 5.5 4.1 53.6 0.24 8.6 11.3 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) CALCOCO1 PF07888.6 ETO06310.1 - 7 4.8 55.2 0.42 8.8 12.3 2.1 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like UXS1_N PF11803.3 ETO06310.1 - 8.4 6.2 19.4 5.3 6.8 0.2 4.7 2 1 2 5 5 5 0 UDP-glucuronate decarboxylase N-terminal WEMBL PF05701.6 ETO06310.1 - 9.5 4.5 60.3 1.3 7.4 13.2 2.2 1 1 1 2 2 2 0 Weak chloroplast movement under blue light WD40 PF00400.27 ETO06311.1 - 9.8e-42 139.3 29.1 4.4e-08 32.7 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO06311.1 - 8.7e-07 28.8 0.4 0.011 15.4 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO06311.1 - 0.00023 19.4 0.2 0.017 13.2 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 VID27 PF08553.5 ETO06311.1 - 0.0086 14.3 0.0 0.017 13.3 0.0 1.4 1 0 0 1 1 1 1 VID27 cytoplasmic protein SYCE1 PF15233.1 ETO06311.1 - 0.057 13.3 3.5 0.089 12.7 2.4 1.2 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 WD40 PF00400.27 ETO06312.1 - 1.9e-76 249.4 24.8 1.2e-11 44.0 0.6 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO06312.1 - 1.4e-15 57.4 0.4 2.7e-07 30.4 0.0 3.5 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO06312.1 - 2.9e-09 35.6 5.9 0.13 10.3 0.0 5.0 2 2 2 4 4 4 4 Nucleoporin Nup120/160 Nbas_N PF15492.1 ETO06312.1 - 7.1e-07 28.6 3.5 0.66 9.0 0.1 4.4 1 1 2 4 4 4 3 Neuroblastoma-amplified sequence, N terminal Coatomer_WDAD PF04053.9 ETO06312.1 - 3.3e-05 22.8 0.4 0.036 12.8 0.0 2.5 1 1 0 2 2 2 2 Coatomer WD associated region PQQ_2 PF13360.1 ETO06312.1 - 0.00033 20.2 0.4 0.0025 17.2 0.2 2.7 1 1 0 1 1 1 1 PQQ-like domain Proteasome_A_N PF10584.4 ETO06312.1 - 0.012 14.9 10.5 3.3 7.1 0.0 4.8 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Resistin PF06954.6 ETO06312.1 - 0.015 15.5 0.8 26 5.1 0.0 4.8 2 2 2 5 5 5 0 Resistin PD40 PF07676.7 ETO06312.1 - 0.98 9.1 11.3 73 3.1 0.0 6.5 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat GDI PF00996.13 ETO06313.1 - 0.017 13.4 0.3 0.038 12.2 0.2 1.5 1 1 0 1 1 1 0 GDP dissociation inhibitor N_NLPC_P60 PF12912.2 ETO06314.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 NLPC_P60 stabilising domain, N term Kelch_6 PF13964.1 ETO06315.1 - 1.1e-09 37.9 6.4 9.5e-06 25.5 0.1 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO06315.1 - 5.7e-07 28.9 13.1 1.1e-05 24.9 0.3 5.6 6 0 0 6 6 6 1 Kelch motif Kelch_4 PF13418.1 ETO06315.1 - 2e-05 24.2 0.3 0.0095 15.6 0.0 3.0 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO06315.1 - 2.8e-05 24.1 0.0 0.00057 19.9 0.0 2.7 2 0 0 2 2 2 1 Galactose oxidase, central domain CENP-O PF09496.5 ETO06315.1 - 0.26 11.5 1.2 31 4.9 0.0 3.0 3 1 1 4 4 4 0 Cenp-O kinetochore centromere component Kelch_2 PF07646.10 ETO06315.1 - 2.4 8.0 7.6 0.86 9.4 0.2 3.6 4 0 0 4 4 4 0 Kelch motif RRM_6 PF14259.1 ETO06316.1 - 9.2e-20 70.4 0.2 9.2e-11 41.5 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO06316.1 - 4.6e-15 54.9 1.8 4.3e-09 35.8 0.0 4.4 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO06316.1 - 2.7e-07 30.3 0.1 0.005 16.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Na_trans_assoc PF06512.8 ETO06316.1 - 0.024 14.5 1.6 0.05 13.5 1.1 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated ATG16 PF08614.6 ETO06318.1 - 1.3e-07 31.6 9.6 1.6e-07 31.3 6.7 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Caudo_TAP PF02413.12 ETO06318.1 - 0.18 11.9 4.3 2.3 8.3 0.0 2.6 1 1 1 2 2 2 0 Caudovirales tail fibre assembly protein SnAC PF14619.1 ETO06318.1 - 0.36 11.0 4.6 0.37 10.9 0.0 2.8 3 1 0 3 3 3 0 Snf2-ATP coupling, chromatin remodelling complex DUF507 PF04368.8 ETO06318.1 - 0.64 9.6 10.5 1.8 8.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF507) Vps39_1 PF10366.4 ETO06318.1 - 1.6 8.7 5.8 0.51 10.3 1.8 1.8 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 DUF972 PF06156.8 ETO06318.1 - 4 7.8 17.7 0.074 13.4 0.9 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF972) ING PF12998.2 ETO06318.1 - 4.7 7.5 11.4 2.5 8.4 0.3 2.3 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF1043 PF06295.7 ETO06318.1 - 8.7 5.9 10.4 5.7 6.5 3.9 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1043) CN_hydrolase PF00795.17 ETO06319.1 - 9e-17 61.0 0.0 3.8e-16 58.9 0.0 1.8 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Zip PF02535.17 ETO06320.1 - 1.9e-21 76.4 6.8 4.4e-16 58.7 1.4 2.8 1 1 2 3 3 3 2 ZIP Zinc transporter DUF3753 PF12575.3 ETO06320.1 - 0.053 13.3 1.0 0.088 12.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) DUF95 PF01944.12 ETO06320.1 - 0.22 11.1 4.1 2.2 7.9 1.0 2.8 2 1 0 2 2 2 0 Integral membrane protein DUF95 WD40 PF00400.27 ETO06321.1 - 5.8e-05 22.8 1.9 0.026 14.4 0.6 4.0 5 0 0 5 5 5 2 WD domain, G-beta repeat WD40 PF00400.27 ETO06322.1 - 1.1e-24 85.3 2.8 1.7e-09 37.1 0.0 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat Pentapeptide PF00805.17 ETO06322.1 - 6.5e-07 28.4 7.2 0.00039 19.5 0.2 2.3 1 1 1 2 2 2 2 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 ETO06322.1 - 8.1e-05 22.4 2.2 0.00019 21.2 1.5 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.1 ETO06322.1 - 0.00015 21.4 2.6 0.00022 20.9 0.8 1.9 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) WAPL PF07814.8 ETO06322.1 - 0.011 14.4 0.2 0.02 13.6 0.2 1.4 1 0 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin DPPIV_N PF00930.16 ETO06322.1 - 0.018 13.6 0.5 0.55 8.7 0.1 2.2 1 1 2 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region UME PF08064.8 ETO06322.1 - 0.091 12.7 0.3 0.18 11.8 0.2 1.4 1 0 0 1 1 1 0 UME (NUC010) domain KAT11 PF08214.6 ETO06324.1 - 0.07 12.1 3.4 0.084 11.9 2.4 1.1 1 0 0 1 1 1 0 Histone acetylation protein DUF506 PF04720.7 ETO06324.1 - 0.11 12.1 5.2 0.14 11.7 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF506) DUF2407_C PF13373.1 ETO06324.1 - 0.86 9.5 0.1 0.86 9.5 0.0 2.1 1 1 1 2 2 2 0 DUF2407 C-terminal domain DNA_repr_REX1B PF14966.1 ETO06326.1 - 0.2 12.0 2.5 0.38 11.1 0.0 2.6 3 0 0 3 3 3 0 DNA repair REX1-B STN1_2 PF09170.5 ETO06326.1 - 0.7 9.6 4.3 1.7 8.4 0.2 3.0 3 0 0 3 3 3 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Peptidase_S49_N PF08496.5 ETO06327.1 - 0.11 12.3 0.3 1.5 8.5 0.3 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DDHD PF02862.12 ETO06328.1 - 6.3 6.5 7.4 6.5 6.4 5.1 1.0 1 0 0 1 1 1 0 DDHD domain Neur_chan_memb PF02932.11 ETO06328.1 - 6.9 6.4 6.6 7 6.4 4.5 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIE-A_C-term PF11521.3 ETO06329.1 - 0.38 10.7 10.0 0.41 10.6 6.9 1.1 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha Spb1_C PF07780.7 ETO06329.1 - 2.6 7.4 6.0 2.4 7.5 4.2 1.0 1 0 0 1 1 1 0 Spb1 C-terminal domain Sigma70_ner PF04546.8 ETO06329.1 - 3.1 7.3 13.9 2.9 7.4 9.7 1.0 1 0 0 1 1 1 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.5 ETO06329.1 - 3.8 7.7 20.6 4.6 7.5 14.3 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.1 ETO06329.1 - 3.9 7.1 7.1 4 7.0 4.9 1.1 1 0 0 1 1 1 0 FAM176 family BTV_NS2 PF04514.7 ETO06329.1 - 7.6 5.3 8.4 7.3 5.3 5.9 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 XAP5 PF04921.9 ETO06329.1 - 9.5 5.7 7.0 9.3 5.7 4.8 1.0 1 0 0 1 1 1 0 XAP5, circadian clock regulator DUF3328 PF11807.3 ETO06330.1 - 0.099 12.3 4.3 4.7 6.8 1.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) WD40 PF00400.27 ETO06331.1 - 2.8e-47 156.9 5.3 4.3e-11 42.2 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO06331.1 - 4.3e-06 26.5 2.6 0.0035 17.0 0.2 3.2 1 1 3 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO06331.1 - 9e-06 24.0 3.4 0.37 8.8 0.0 4.2 1 1 3 4 4 4 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO06331.1 - 4.7e-05 23.1 2.3 0.33 10.7 0.0 3.1 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region PD40 PF07676.7 ETO06331.1 - 8.1e-05 22.1 0.3 0.26 11.0 0.0 3.8 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat B_lectin PF01453.19 ETO06331.1 - 0.00034 20.4 0.1 0.11 12.3 0.0 2.4 1 1 1 2 2 2 2 D-mannose binding lectin Nucleoporin_N PF08801.6 ETO06331.1 - 0.0091 14.7 7.4 0.2 10.3 5.1 3.0 1 1 0 1 1 1 1 Nup133 N terminal like Methyltransf_3 PF01596.12 ETO06331.1 - 0.051 12.6 0.0 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 O-methyltransferase Hira PF07569.6 ETO06331.1 - 0.057 12.6 1.5 8.9 5.4 0.0 3.6 1 1 3 4 4 4 0 TUP1-like enhancer of split Nsp1_C PF05064.8 ETO06331.1 - 0.058 13.0 0.1 0.16 11.5 0.0 1.8 1 0 0 1 1 1 0 Nsp1-like C-terminal region TPR_12 PF13424.1 ETO06332.1 - 4.8e-68 225.0 8.8 7.5e-22 77.0 0.6 4.6 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO06332.1 - 2.8e-51 171.0 32.3 4.6e-13 48.6 1.0 6.1 2 1 5 7 7 7 6 TPR repeat TPR_1 PF00515.23 ETO06332.1 - 1.9e-45 150.6 23.7 2.5e-09 36.3 0.2 7.6 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.1 ETO06332.1 - 1.6e-39 130.5 1.3 1.6e-05 24.3 0.0 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_10 PF13374.1 ETO06332.1 - 2e-39 132.4 0.0 1.3e-07 31.2 0.0 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.12 ETO06332.1 - 1.3e-32 109.0 15.7 2.3e-06 27.0 0.2 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETO06332.1 - 3e-32 107.9 25.1 9.7e-07 28.1 0.4 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.1 ETO06332.1 - 7.2e-17 60.1 5.0 0.012 15.7 0.0 7.7 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO06332.1 - 1.2e-12 47.3 0.0 1.8 9.4 0.0 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO06332.1 - 2.3e-11 43.3 1.9 0.83 10.2 0.0 6.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO06332.1 - 9.1e-10 38.9 0.1 0.11 13.2 0.0 4.3 1 1 4 5 5 5 4 Tetratricopeptide repeat MIT PF04212.13 ETO06332.1 - 2.5e-07 30.4 16.8 0.31 10.9 0.1 7.4 7 1 1 8 8 8 2 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 ETO06332.1 - 7.1e-07 28.8 6.2 0.00085 19.0 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO06332.1 - 1.7e-06 27.1 1.8 1.4 8.2 0.0 5.4 6 0 0 6 6 6 2 SHNi-TPR PPR PF01535.15 ETO06332.1 - 6.1e-06 25.8 7.4 2.3 8.3 0.0 6.8 8 0 0 8 8 8 1 PPR repeat Apc3 PF12895.2 ETO06332.1 - 3.7e-05 23.7 11.8 0.061 13.4 1.1 4.9 1 1 5 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF2225 PF09986.4 ETO06332.1 - 0.00028 20.3 9.8 0.12 11.8 0.1 3.8 1 1 2 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) Sel1 PF08238.7 ETO06332.1 - 0.22 12.2 5.7 37 5.1 0.2 4.7 5 0 0 5 5 4 0 Sel1 repeat EF-hand_1 PF00036.27 ETO06333.1 - 5.8e-19 65.8 0.6 2e-06 26.7 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 ETO06333.1 - 6.9e-16 58.1 0.3 3.7e-08 33.3 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO06333.1 - 7.1e-15 53.4 2.7 5.6e-05 22.6 0.1 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 ETO06333.1 - 1.9e-14 52.9 3.4 1.7e-07 30.7 0.2 3.2 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 ETO06333.1 - 1.5e-10 39.9 9.3 0.003 16.8 0.2 3.5 4 0 0 4 4 4 3 EF hand RuvA_C PF07499.8 ETO06333.1 - 2.8e-08 33.7 0.3 0.0013 18.8 0.0 2.7 3 0 0 3 3 3 2 RuvA, C-terminal domain EF-hand_4 PF12763.2 ETO06333.1 - 2.2e-05 24.1 0.5 0.0049 16.5 0.1 2.9 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand UB2H PF14814.1 ETO06333.1 - 0.0013 18.4 0.1 0.085 12.5 0.0 2.9 2 1 1 3 3 3 1 Bifunctional transglycosylase second domain Antig_Caf1 PF09255.5 ETO06333.1 - 0.011 15.6 0.0 0.066 13.1 0.0 1.8 1 1 1 2 2 2 0 Caf1 Capsule antigen SPARC_Ca_bdg PF10591.4 ETO06333.1 - 0.014 15.3 0.0 0.32 11.0 0.0 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region UBA PF00627.26 ETO06333.1 - 0.073 12.9 0.0 7.5 6.5 0.0 2.5 2 0 0 2 2 2 0 UBA/TS-N domain DUF2407_C PF13373.1 ETO06333.1 - 0.081 12.8 0.2 1.2 9.1 0.0 2.2 2 1 0 2 2 2 0 DUF2407 C-terminal domain ABC_tran PF00005.22 ETO06334.1 - 8.9e-11 42.2 0.0 1.1e-10 41.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 ETO06334.1 - 6.9e-05 22.9 0.0 7.5e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 ETO06334.1 - 0.0082 15.3 0.0 0.0094 15.2 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 ETO06334.1 - 0.0091 15.8 0.0 0.085 12.7 0.0 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Myc_target_1 PF15179.1 ETO06335.1 - 0.047 13.2 0.4 0.047 13.2 0.3 1.8 2 0 0 2 2 2 0 Myc target protein 1 RHINO PF15319.1 ETO06336.1 - 0.029 14.1 2.3 0.034 13.9 1.6 1.1 1 0 0 1 1 1 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein SCF PF02404.10 ETO06337.1 - 0.024 13.8 0.6 0.026 13.7 0.4 1.1 1 0 0 1 1 1 0 Stem cell factor VPS28 PF03997.7 ETO06337.1 - 0.031 13.9 0.3 0.031 13.9 0.2 1.1 1 0 0 1 1 1 0 VPS28 protein UBN2_3 PF14244.1 ETO06337.1 - 0.048 13.2 0.7 0.05 13.1 0.5 1.1 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Hrs_helical PF12210.3 ETO06337.1 - 0.13 12.4 1.6 0.18 12.0 0.4 1.7 1 1 1 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate HalX PF08663.5 ETO06337.1 - 0.14 12.1 1.0 14 5.7 0.0 2.2 2 0 0 2 2 2 0 HalX domain HTH_40 PF14493.1 ETO06337.1 - 0.3 11.3 2.4 0.7 10.1 1.5 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain Eaf7 PF07904.8 ETO06337.1 - 0.48 10.4 3.8 0.69 9.9 2.7 1.4 1 1 0 1 1 1 0 Chromatin modification-related protein EAF7 DUF2951 PF11166.3 ETO06337.1 - 0.56 10.0 6.4 0.82 9.5 4.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2951) DUF1493 PF07377.7 ETO06338.1 - 0.0044 17.1 0.1 0.0071 16.4 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1493) WD40 PF00400.27 ETO06339.1 - 2.5e-05 23.9 0.1 4.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 WD domain, G-beta repeat DUF641 PF04859.7 ETO06339.1 - 0.034 13.8 0.9 0.067 12.9 0.6 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) MRL1 PF13003.2 ETO06339.1 - 0.064 13.0 8.0 0.67 9.7 0.9 2.1 2 0 0 2 2 2 0 Ribosomal protein L1 RNB PF00773.14 ETO06339.1 - 0.088 12.0 2.6 0.094 11.9 1.8 1.1 1 0 0 1 1 1 0 RNB domain RVP PF00077.15 ETO06339.1 - 0.21 11.5 1.8 1.8 8.5 0.3 2.2 2 0 0 2 2 2 0 Retroviral aspartyl protease zf-C3HC4_2 PF13923.1 ETO06339.1 - 1.1 9.3 10.9 0.19 11.7 1.1 3.5 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF1644 PF07800.7 ETO06339.1 - 2.4 7.9 12.9 4.6 7.0 1.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) EBA-175_VI PF11556.3 ETO06339.1 - 6.3 6.9 12.7 4.9 7.3 1.8 2.3 1 1 1 2 2 2 0 Erythrocyte binding antigen 175 zf-RING-like PF08746.6 ETO06339.1 - 7.8 6.5 8.5 0.48 10.4 0.3 2.8 2 1 1 3 3 3 0 RING-like domain WD40 PF00400.27 ETO06340.1 - 1.7e-17 62.5 12.6 2.2e-08 33.6 0.8 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO06340.1 - 0.00082 17.6 1.6 0.0046 15.1 0.3 2.1 1 1 1 2 2 2 1 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO06340.1 - 0.052 12.8 9.8 0.047 13.0 2.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4221) DUF1371 PF07115.6 ETO06343.1 - 1 9.5 9.5 0.54 10.4 5.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1371) DUF4535 PF15054.1 ETO06343.1 - 1.2 8.5 6.6 0.34 10.3 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4535) WD40 PF00400.27 ETO06344.1 - 1.3e-23 81.9 5.0 3.8e-09 36.0 0.3 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO06344.1 - 0.00016 19.9 2.3 0.11 10.6 0.3 2.9 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO06344.1 - 0.0026 16.5 6.0 0.22 10.2 4.2 2.2 1 1 0 1 1 1 1 Nup133 N terminal like DUF2258 PF10015.4 ETO06345.1 - 0.053 13.3 0.2 0.24 11.2 0.0 2.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2258) ETRAMP PF09716.5 ETO06346.1 - 0.14 12.1 0.3 0.14 12.1 0.2 4.1 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) PDR_CDR PF06422.7 ETO06346.1 - 0.24 11.1 1.9 2.4 7.8 0.0 3.0 3 0 0 3 3 3 0 CDR ABC transporter O-antigen_lig PF13425.1 ETO06346.1 - 0.95 9.4 3.8 0.7 9.8 0.1 2.2 2 0 0 2 2 2 0 O-antigen ligase like membrane protein Baculo_11_kDa PF06143.6 ETO06346.1 - 5.3 6.4 7.0 5.7 6.3 1.9 2.8 2 0 0 2 2 2 0 Baculovirus 11 kDa family WD40 PF00400.27 ETO06347.1 - 1.3e-34 116.8 13.9 1e-11 44.1 0.3 4.6 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO06347.1 - 2.1e-05 22.8 2.1 0.3 9.1 0.0 3.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 DUF851 PF05867.6 ETO06347.1 - 0.11 11.7 0.0 0.29 10.3 0.0 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF851) SopA PF13981.1 ETO06348.1 - 0.013 15.5 1.0 0.017 15.1 0.7 1.2 1 0 0 1 1 1 0 SopA-like central domain Peptidase_M54 PF07998.6 ETO06348.1 - 0.024 14.3 0.8 0.059 13.1 0.1 1.8 2 0 0 2 2 2 0 Peptidase family M54 NEMO PF11577.3 ETO06348.1 - 6.4 6.6 7.2 1.2 8.9 1.0 2.4 1 1 1 2 2 2 0 NF-kappa-B essential modulator NEMO Folate_carrier PF01770.13 ETO06351.1 - 0.0073 14.8 0.1 0.01 14.3 0.1 1.1 1 0 0 1 1 1 1 Reduced folate carrier SID-1_RNA_chan PF13965.1 ETO06351.1 - 0.025 12.7 0.2 0.033 12.3 0.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Tetraspannin PF00335.15 ETO06351.1 - 0.3 10.3 3.5 0.43 9.8 2.5 1.4 1 1 0 1 1 1 0 Tetraspanin family Peptidase_C48 PF02902.14 ETO06352.1 - 0.11 12.1 3.7 0.59 9.7 0.9 2.2 2 0 0 2 2 2 0 Ulp1 protease family, C-terminal catalytic domain Kelch_6 PF13964.1 ETO06353.1 - 3.3e-06 27.0 2.5 0.36 11.0 0.0 4.7 4 1 1 5 5 5 3 Kelch motif Kelch_1 PF01344.20 ETO06353.1 - 4e-06 26.2 0.6 0.28 10.7 0.1 3.9 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 ETO06353.1 - 0.0015 18.2 0.5 15 5.5 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO06353.1 - 0.14 11.9 0.1 3.7 7.3 0.0 2.8 1 1 1 2 2 2 0 Galactose oxidase, central domain zf-C3HC4_2 PF13923.1 ETO06354.1 - 0.0016 18.4 0.5 0.015 15.3 0.3 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO06354.1 - 0.002 17.9 0.8 0.0059 16.4 0.6 1.8 1 1 0 1 1 1 1 Ring finger domain DDDD PF10161.4 ETO06354.1 - 0.055 13.0 0.3 5.5 6.6 0.1 2.2 2 0 0 2 2 2 0 Putative mitochondrial precursor protein zf-C3HC4_3 PF13920.1 ETO06354.1 - 0.51 10.0 4.0 3.4 7.4 2.8 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3447 PF11929.3 ETO06354.1 - 2.7 7.8 6.3 3.9 7.3 3.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3447) RNase_H PF00075.19 ETO06355.1 - 1.3e-06 28.7 0.1 2.1e-05 24.8 0.0 2.0 1 1 1 2 2 2 1 RNase H SAM_1 PF00536.25 ETO06357.1 - 1.3e-07 31.6 0.3 2.9e-07 30.5 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 ETO06357.1 - 5.2e-05 22.9 1.2 0.00012 21.7 0.2 2.0 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain SAM_2 PF07647.12 ETO06357.1 - 6.3e-05 22.7 0.6 0.00017 21.3 0.1 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) CCSMST1 PF15013.1 ETO06357.1 - 0.14 12.0 2.8 0.62 10.0 1.9 2.1 1 1 0 1 1 1 0 CCSMST1 family Polyoma_agno PF01736.11 ETO06358.1 - 2.2 7.9 4.9 4.3 7.0 0.0 3.2 4 0 0 4 4 4 0 Polyomavirus agnoprotein XPA_C PF05181.7 ETO06359.1 - 0.077 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 XPA protein C-terminus Rhodanese PF00581.15 ETO06360.1 - 1.8e-36 124.9 0.1 2.1e-18 66.7 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain Glyco_hydro_17 PF00332.13 ETO06360.1 - 0.0019 17.3 0.0 0.0045 16.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 TPR_1 PF00515.23 ETO06361.1 - 5.1e-05 22.7 0.2 0.00014 21.3 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO06361.1 - 0.00067 19.2 0.1 0.0015 18.1 0.1 1.6 1 0 0 1 1 1 1 TPR repeat TPR_8 PF13181.1 ETO06361.1 - 0.0013 18.3 2.4 0.0019 17.8 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO06361.1 - 0.0015 18.2 0.3 0.0035 17.1 0.2 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO06361.1 - 0.051 13.5 0.2 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETO06361.1 - 0.13 12.9 0.1 0.27 11.9 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat BCIP PF13862.1 ETO06361.1 - 2 7.8 9.3 2.3 7.6 2.1 2.5 3 0 0 3 3 3 0 p21-C-terminal region-binding protein IBR PF01485.16 ETO06363.1 - 1.5e-11 43.9 26.0 5.7e-10 38.9 6.6 4.2 4 1 0 4 4 4 2 IBR domain zf-C3HC4 PF00097.20 ETO06363.1 - 2.7e-05 23.7 5.8 2.7e-05 23.7 4.0 6.1 5 1 1 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 ETO06363.1 - 0.0019 17.8 3.0 0.0019 17.8 2.1 4.1 4 0 0 4 4 4 1 RING-type zinc-finger zf-RING_2 PF13639.1 ETO06363.1 - 0.0056 16.4 6.5 0.0056 16.4 4.5 4.7 3 1 1 4 4 4 1 Ring finger domain zf-RING_5 PF14634.1 ETO06363.1 - 0.014 15.1 8.4 0.014 15.1 5.9 5.4 3 2 2 5 5 5 0 zinc-RING finger domain XK-related PF09815.4 ETO06363.1 - 0.07 12.1 2.5 0.12 11.3 1.7 1.3 1 0 0 1 1 1 0 XK-related protein DUF3987 PF13148.1 ETO06367.1 - 0.069 11.6 17.3 0.13 10.7 12.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AF-4 PF05110.8 ETO06367.1 - 0.23 9.2 35.0 0.25 9.1 24.3 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein mRNA_cap_enzyme PF01331.14 ETO06368.1 - 0.0086 15.7 1.3 0.029 14.0 0.9 2.0 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain DDRGK PF09756.4 ETO06370.1 - 0.32 10.3 10.8 0.91 8.9 2.8 2.5 2 0 0 2 2 2 0 DDRGK domain PRO8NT PF08082.6 ETO06370.1 - 0.32 10.6 2.1 0.6 9.7 1.5 1.4 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain zf-C3HC4_2 PF13923.1 ETO06371.1 - 0.02 14.8 1.3 0.1 12.6 0.9 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4404 PF14357.1 ETO06371.1 - 1.4 9.3 10.4 0.4 11.1 3.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) GOLD_2 PF13897.1 ETO06372.1 - 0.058 13.6 0.6 0.065 13.4 0.4 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Peptidase_S49_N PF08496.5 ETO06372.1 - 0.09 12.5 7.2 0.085 12.6 5.0 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CENP-C_mid PF15620.1 ETO06372.1 - 0.11 12.2 10.0 0.12 12.0 6.9 1.0 1 0 0 1 1 1 0 Centromere assembly component CENP-C middle DNMT3B-binding region tRNA-synt_1_2 PF13603.1 ETO06372.1 - 0.17 11.1 1.9 0.18 11.0 1.3 1.0 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 Sec62 PF03839.11 ETO06372.1 - 0.17 11.2 8.7 0.21 10.9 6.1 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 AAA_23 PF13476.1 ETO06372.1 - 0.17 12.1 7.4 0.2 11.9 5.1 1.0 1 0 0 1 1 1 0 AAA domain OATP PF03137.15 ETO06372.1 - 0.23 9.4 2.8 0.23 9.4 2.0 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family FemAB PF02388.11 ETO06372.1 - 0.24 10.0 5.4 0.24 10.0 3.7 1.0 1 0 0 1 1 1 0 FemAB family Trypan_glycop PF00913.14 ETO06372.1 - 2 7.2 8.9 2.1 7.1 6.2 1.0 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) M16C_assoc PF08367.6 ETO06372.1 - 2.4 6.9 8.2 3 6.6 5.7 1.1 1 0 0 1 1 1 0 Peptidase M16C associated DUF2098 PF09871.4 ETO06372.1 - 5.5 6.9 9.7 7 6.6 6.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) BHD_2 PF10404.4 ETO06372.1 - 6.9 7.0 7.9 13 6.1 5.5 1.6 1 1 0 1 1 1 0 Rad4 beta-hairpin domain 2 DUF3464 PF11947.3 ETO06372.1 - 7 6.0 6.5 8.5 5.8 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) RRM_1 PF00076.17 ETO06373.1 - 1.2e-15 56.9 0.0 2.4e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO06373.1 - 6.3e-10 38.8 0.0 1.2e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO06373.1 - 9.7e-07 28.5 0.0 1.8e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 ETO06373.1 - 0.0055 16.6 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 RNA binding domain Blt1 PF12754.2 ETO06374.1 - 0.022 14.3 0.1 0.028 14.0 0.1 1.1 1 0 0 1 1 1 0 Cell-cycle control medial ring component Histidinol_dh PF00815.15 ETO06374.1 - 0.054 12.1 0.3 0.064 11.8 0.2 1.1 1 0 0 1 1 1 0 Histidinol dehydrogenase Raftlin PF15250.1 ETO06375.1 - 0.35 9.3 11.5 0.53 8.7 8.0 1.3 1 0 0 1 1 1 0 Raftlin DUF4175 PF13779.1 ETO06375.1 - 5 4.7 7.3 17 2.9 3.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) DUF4638 PF15472.1 ETO06375.1 - 8.6 5.8 10.5 6.6 6.2 5.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4638) Ipi1_N PF12333.3 ETO06376.1 - 0.0012 18.7 2.6 0.003 17.4 0.2 2.8 3 1 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation RhoGAP PF00620.22 ETO06376.1 - 0.041 13.4 0.8 0.13 11.8 0.1 2.2 1 1 0 2 2 2 0 RhoGAP domain WD40 PF00400.27 ETO06377.1 - 5.3e-41 137.0 14.4 7.4e-08 31.9 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO06377.1 - 0.00018 19.8 7.6 0.4 8.7 0.7 4.2 1 1 2 3 3 3 3 Nucleoporin Nup120/160 WD40 PF00400.27 ETO06378.1 - 2.6e-12 46.0 1.7 4.3e-10 39.0 0.3 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO06378.1 - 1.5e-05 23.3 0.2 1.8e-05 23.1 0.1 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 ATP-synt_B PF00430.13 ETO06379.1 - 0.046 13.5 0.6 0.073 12.8 0.4 1.4 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) Z1 PF10593.4 ETO06379.1 - 0.057 12.6 0.9 0.071 12.3 0.6 1.2 1 0 0 1 1 1 0 Z1 domain DUF2433 PF10360.4 ETO06379.1 - 0.068 13.4 0.3 0.13 12.5 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2433) SSFA2_C PF14723.1 ETO06379.1 - 0.072 12.8 0.9 0.08 12.6 0.6 1.2 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus Dzip-like_N PF13815.1 ETO06379.1 - 0.11 12.2 5.4 0.19 11.5 3.6 1.4 1 1 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal ATP-synt_E_2 PF08112.6 ETO06379.1 - 0.21 11.6 1.8 15 5.7 0.2 2.9 1 1 1 2 2 2 0 ATP synthase epsilon subunit DUF1507 PF07408.6 ETO06379.1 - 0.46 10.2 3.4 2.5 7.9 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1507) Fib_alpha PF08702.5 ETO06379.1 - 0.81 9.7 5.4 1.3 9.1 3.7 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Ank_2 PF12796.2 ETO06380.1 - 1.9e-11 44.1 0.1 6.5e-11 42.4 0.1 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO06380.1 - 2.5e-10 39.5 0.3 0.00012 22.0 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 ETO06380.1 - 3.8e-10 39.0 0.1 0.00022 20.8 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 ETO06380.1 - 1.3e-09 38.2 0.0 9.8e-09 35.4 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO06380.1 - 1.4e-07 31.5 0.6 0.00017 21.7 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF2773 PF10971.3 ETO06380.1 - 0.086 12.8 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2773) Ebola_NP PF05505.7 ETO06382.1 - 0.16 9.9 14.0 0.21 9.6 9.7 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein S_layer_N PF05123.7 ETO06382.1 - 0.53 9.8 13.7 4.1 6.9 3.3 2.2 1 1 1 2 2 2 0 S-layer like family, N-terminal region CRAL_TRIO PF00650.15 ETO06384.1 - 1.1e-11 44.4 4.7 3.1e-09 36.5 1.5 2.1 1 1 1 2 2 2 2 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 ETO06384.1 - 7.6e-05 22.6 2.6 0.00069 19.5 1.8 2.0 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Ndc1_Nup PF09531.5 ETO06385.1 - 2 6.7 5.3 2.3 6.5 3.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3366 PF11846.3 ETO06387.1 - 3.7 7.3 4.9 2.5 7.9 0.1 2.8 2 2 2 4 4 4 0 Domain of unknown function (DUF3366) Baculo_11_kDa PF06143.6 ETO06387.1 - 5.9 6.3 8.4 1.5 8.2 0.1 3.2 2 1 1 3 3 3 0 Baculovirus 11 kDa family PAH PF02671.16 ETO06388.1 - 0.0032 17.0 0.1 0.0085 15.6 0.0 1.7 1 0 0 1 1 1 1 Paired amphipathic helix repeat DUF2458 PF10454.4 ETO06388.1 - 4.1 7.2 11.4 1.2 9.0 5.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) DUF4379 PF14311.1 ETO06389.1 - 0.062 13.1 1.3 0.2 11.5 0.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4379) YebF PF13995.1 ETO06390.1 - 5.2 7.1 7.6 3.9 7.5 0.1 3.1 3 1 0 3 3 3 0 YebF-like protein Myb_DNA-bind_3 PF12776.2 ETO06390.1 - 6 7.5 10.5 0.18 12.4 1.3 2.3 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain Kelch_6 PF13964.1 ETO06391.1 - 0.00021 21.3 0.4 0.00078 19.5 0.1 2.0 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.1 ETO06391.1 - 0.0023 17.8 0.1 0.36 10.8 0.0 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.20 ETO06391.1 - 0.0035 16.8 0.3 0.0079 15.7 0.2 1.7 1 0 0 1 1 1 1 Kelch motif Kelch_2 PF07646.10 ETO06391.1 - 0.12 12.1 0.3 3 7.7 0.0 2.5 2 0 0 2 2 2 0 Kelch motif NS3_envE PF02723.9 ETO06391.1 - 0.37 10.7 5.9 0.82 9.6 4.1 1.6 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E zf-TRAF PF02176.13 ETO06392.1 - 1.3e-11 44.6 6.4 1.3e-11 44.6 4.4 2.3 2 0 0 2 2 2 1 TRAF-type zinc finger PH PF00169.24 ETO06392.1 - 6.2e-05 23.1 1.3 0.00012 22.2 0.0 2.0 2 1 0 2 2 2 1 PH domain PH_11 PF15413.1 ETO06392.1 - 8.1e-05 22.8 0.1 8.1e-05 22.8 0.1 3.1 2 1 0 2 2 2 1 Pleckstrin homology domain TelA PF05816.6 ETO06392.1 - 0.00028 19.7 4.4 0.00042 19.1 3.1 1.3 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) PH_3 PF14593.1 ETO06392.1 - 0.0016 18.2 1.4 0.0099 15.7 0.0 2.4 2 0 0 2 2 2 1 PH domain DUF4047 PF13256.1 ETO06392.1 - 0.093 12.6 6.8 0.029 14.3 1.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) PH_8 PF15409.1 ETO06392.1 - 0.14 12.1 0.2 0.14 12.1 0.1 2.2 2 1 1 3 3 3 0 Pleckstrin homology domain Reo_sigmaC PF04582.7 ETO06392.1 - 0.28 10.3 6.0 0.38 9.8 4.2 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 ETO06392.1 - 0.45 10.3 5.1 0.19 11.5 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) IBR PF01485.16 ETO06392.1 - 0.72 9.7 8.0 17 5.3 3.7 2.4 2 0 0 2 2 2 0 IBR domain IncA PF04156.9 ETO06392.1 - 3.3 7.2 11.5 19 4.7 7.3 2.5 1 1 0 1 1 1 0 IncA protein Serpin PF00079.15 ETO06393.1 - 1.2e-08 34.5 1.2 6.1e-08 32.1 0.9 1.8 1 1 0 1 1 1 1 Serpin (serine protease inhibitor) DUF1363 PF07101.6 ETO06393.1 - 0.0035 17.4 0.1 0.0062 16.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1363) C1_1 PF00130.17 ETO06393.1 - 0.036 13.7 0.7 5.8 6.7 0.2 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_3 PF13920.1 ETO06394.1 - 0.00076 19.0 6.9 0.00076 19.0 4.8 4.3 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO06394.1 - 0.0036 17.0 10.5 0.0036 17.0 7.2 4.4 5 0 0 5 5 5 1 zinc-RING finger domain DNA_primase_S PF01896.14 ETO06394.1 - 0.0096 15.7 4.7 0.01 15.6 1.9 2.1 2 1 0 2 2 2 1 Eukaryotic and archaeal DNA primase small subunit zf-RING_2 PF13639.1 ETO06394.1 - 0.014 15.1 9.5 0.014 15.1 6.6 4.2 5 0 0 5 5 5 0 Ring finger domain Zip PF02535.17 ETO06395.1 - 0.021 13.8 3.3 0.025 13.5 0.1 2.5 3 0 0 3 3 3 0 ZIP Zinc transporter NARP1 PF12569.3 ETO06395.1 - 1.2 7.7 29.9 0.039 12.7 12.3 2.3 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Bap31 PF05529.7 ETO06395.1 - 3.8 6.9 0.0 3.8 6.9 0.0 3.7 3 1 0 3 3 3 0 B-cell receptor-associated protein 31-like DUF966 PF06136.8 ETO06395.1 - 6.1 6.1 21.4 0.094 12.1 9.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF966) SUR7 PF06687.7 ETO06397.1 - 0.53 9.7 6.7 1 8.8 4.7 1.5 1 1 0 1 1 1 0 SUR7/PalI family zf-TRAF PF02176.13 ETO06398.1 - 0.0051 17.1 1.1 0.0051 17.1 0.7 2.3 3 0 0 3 3 3 1 TRAF-type zinc finger Kelch_4 PF13418.1 ETO06399.1 - 9.3e-08 31.7 0.2 0.0059 16.3 0.1 2.4 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO06399.1 - 1.1e-05 25.2 0.2 0.18 11.8 0.3 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.20 ETO06399.1 - 2.2e-05 23.8 1.4 7.1e-05 22.2 0.6 2.0 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETO06399.1 - 0.00068 19.7 1.7 0.15 12.2 0.2 2.4 1 1 1 2 2 2 2 Kelch motif Kelch_3 PF13415.1 ETO06399.1 - 0.0059 16.7 0.0 0.017 15.3 0.0 1.7 2 0 0 2 2 2 1 Galactose oxidase, central domain COX7a PF02238.10 ETO06399.1 - 0.13 12.0 0.1 0.93 9.2 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIa Innate_immun PF12782.2 ETO06400.1 - 0.023 13.9 0.9 0.026 13.7 0.6 1.0 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family DUF3380 PF11860.3 ETO06400.1 - 0.039 13.9 1.2 0.044 13.8 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3380) DsrC PF04358.8 ETO06400.1 - 0.1 12.8 2.1 0.13 12.5 1.4 1.2 1 0 0 1 1 1 0 DsrC like protein DUF2228 PF10228.4 ETO06400.1 - 3.9 6.9 8.1 3 7.3 4.9 1.3 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) DUF4604 PF15377.1 ETO06400.1 - 4.1 7.6 12.0 4.8 7.3 8.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) FAM60A PF15396.1 ETO06401.1 - 0.0045 16.7 1.2 0.0045 16.7 0.8 1.5 2 0 0 2 2 2 1 Protein Family FAM60A Sod_Fe_N PF00081.17 ETO06401.1 - 0.15 12.3 1.1 0.31 11.3 0.3 1.8 2 0 0 2 2 2 0 Iron/manganese superoxide dismutases, alpha-hairpin domain TMEMspv1-c74-12 PF11044.3 ETO06401.1 - 0.3 10.6 0.1 0.3 10.6 0.1 2.1 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Ycf1 PF05758.7 ETO06402.1 - 0.0034 15.1 0.0 0.0037 15.0 0.0 1.1 1 0 0 1 1 1 1 Ycf1 SAM_2 PF07647.12 ETO06404.1 - 0.0043 16.8 0.1 0.0088 15.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO06404.1 - 0.0045 17.1 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) TMEM154 PF15102.1 ETO06404.1 - 1.5 8.5 4.6 0.24 11.1 0.1 2.0 2 0 0 2 2 2 0 TMEM154 protein family MIP PF00230.15 ETO06405.1 - 7.5e-19 68.0 1.4 1.2e-18 67.4 1.0 1.3 1 1 0 1 1 1 1 Major intrinsic protein ABC_tran PF00005.22 ETO06406.1 - 0.002 18.4 0.7 0.014 15.7 0.0 2.1 2 0 0 2 2 2 1 ABC transporter Sod_Ni PF09055.6 ETO06406.1 - 0.0037 17.6 0.5 0.0061 16.9 0.4 1.3 1 0 0 1 1 1 1 Nickel-containing superoxide dismutase AAA PF00004.24 ETO06406.1 - 0.014 15.5 0.2 0.04 14.1 0.1 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETO06406.1 - 0.015 15.4 0.0 0.046 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 ETO06406.1 - 0.043 13.8 0.0 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain PduV-EutP PF10662.4 ETO06406.1 - 0.059 12.8 0.7 0.13 11.7 0.1 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.21 ETO06406.1 - 0.065 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain T2SE PF00437.15 ETO06406.1 - 0.11 11.3 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.9 ETO06406.1 - 0.12 12.1 0.1 0.24 11.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 ETO06406.1 - 0.15 12.2 1.1 0.53 10.4 0.0 2.4 2 1 0 2 2 2 0 RNA helicase AAA_16 PF13191.1 ETO06406.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain HAD_2 PF13419.1 ETO06407.1 - 0.076 13.2 0.9 4.3 7.5 0.0 3.3 3 1 0 3 3 3 0 Haloacid dehalogenase-like hydrolase FeoA PF04023.9 ETO06408.1 - 0.11 12.5 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 FeoA domain NACHT PF05729.7 ETO06409.1 - 2.5e-09 37.0 0.0 5e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain RelA_SpoT PF04607.12 ETO06409.1 - 1.1e-05 25.4 4.1 4.7e-05 23.3 0.7 2.7 2 0 0 2 2 2 1 Region found in RelA / SpoT proteins AAA_18 PF13238.1 ETO06409.1 - 0.00024 21.4 0.9 0.001 19.3 0.0 2.5 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.1 ETO06409.1 - 0.0053 16.9 0.0 0.016 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO06409.1 - 0.01 16.6 0.5 0.098 13.4 0.0 2.8 2 1 1 3 3 3 0 AAA domain ABC_tran PF00005.22 ETO06409.1 - 0.012 15.9 0.0 0.031 14.5 0.0 1.8 1 0 0 1 1 1 0 ABC transporter UPF0079 PF02367.12 ETO06409.1 - 0.022 14.3 0.0 0.065 12.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 ETO06409.1 - 0.059 12.4 0.0 0.2 10.7 0.0 1.9 1 0 0 1 1 1 0 Zeta toxin WD40 PF00400.27 ETO06410.1 - 8.2e-128 412.2 47.0 1e-10 41.0 0.0 15.3 15 0 0 15 15 15 15 WD domain, G-beta repeat Mid2 PF04478.7 ETO06410.1 - 0.0014 18.0 7.7 0.051 12.9 0.0 6.1 4 3 4 8 8 8 1 Mid2 like cell wall stress sensor Pentapeptide PF00805.17 ETO06410.1 - 0.0018 17.4 0.6 0.011 14.8 0.6 2.4 2 0 0 2 2 2 1 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 ETO06410.1 - 0.017 14.9 2.4 0.16 11.8 1.6 2.9 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.1 ETO06410.1 - 0.061 13.1 4.3 0.062 13.1 0.3 3.1 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) QLQ PF08880.6 ETO06410.1 - 3.1 7.2 5.4 1.1e+02 2.3 0.5 3.8 3 0 0 3 3 3 0 QLQ Phospholip_B PF04916.8 ETO06411.1 - 4.8e-24 84.4 0.1 5.6e-24 84.1 0.1 1.0 1 0 0 1 1 1 1 Phospholipase B XH PF03469.9 ETO06411.1 - 0.056 13.0 0.0 0.095 12.3 0.0 1.3 1 0 0 1 1 1 0 XH domain HEAT_2 PF13646.1 ETO06412.1 - 5.4e-19 68.2 0.0 0.00037 20.7 0.0 5.9 2 1 3 6 6 6 6 HEAT repeats HEAT PF02985.17 ETO06412.1 - 3.8e-18 63.8 0.0 0.0057 16.6 0.0 8.7 8 1 1 9 9 9 4 HEAT repeat HEAT_EZ PF13513.1 ETO06412.1 - 8.1e-10 38.8 0.0 0.59 10.7 0.0 7.1 5 2 2 7 7 7 1 HEAT-like repeat Cnd1 PF12717.2 ETO06412.1 - 4.8e-05 23.2 23.1 0.013 15.3 1.5 5.4 2 1 4 6 6 6 5 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 ETO06412.1 - 0.00039 20.7 7.8 0.38 11.1 0.0 5.0 3 2 2 5 5 5 2 Vacuolar 14 Fab1-binding region UME PF08064.8 ETO06412.1 - 0.0048 16.8 1.3 8.1 6.4 0.0 4.2 3 1 0 4 4 4 1 UME (NUC010) domain DNA_pol3_gamma3 PF12169.3 ETO06412.1 - 0.027 14.2 0.0 40 3.9 0.0 4.3 3 1 1 4 4 4 0 DNA polymerase III subunits gamma and tau domain III DUF2543 PF10820.3 ETO06412.1 - 0.048 13.6 0.6 2.4 8.2 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2543) Med11 PF10280.4 ETO06412.1 - 0.077 13.0 1.6 0.26 11.3 0.3 2.4 2 0 0 2 2 2 0 Mediator complex protein DUF3944 PF13099.1 ETO06412.1 - 0.18 11.2 6.9 3.1 7.3 0.1 4.7 4 0 0 4 4 4 0 Domain of unknown function (DUF3944) DERM PF14704.1 ETO06412.1 - 3.1 7.7 9.4 3.1 7.7 0.1 3.6 3 1 1 4 4 4 0 Dermatopontin Dpy19 PF10034.4 ETO06415.1 - 0.042 12.0 3.8 0.07 11.3 2.6 1.3 1 0 0 1 1 1 0 Q-cell neuroblast polarisation PAPA-1 PF04795.7 ETO06415.1 - 0.76 10.5 5.0 1.3 9.8 3.5 1.3 1 0 0 1 1 1 0 PAPA-1-like conserved region WD40 PF00400.27 ETO06416.1 - 8.9e-20 69.7 0.3 3.8e-14 51.9 0.1 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat Pentapeptide_3 PF13576.1 ETO06416.1 - 0.00045 20.0 1.5 0.0012 18.6 1.0 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.1 ETO06416.1 - 0.0012 18.5 2.6 0.0039 16.9 1.8 2.0 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETO06416.1 - 0.0083 15.3 0.9 0.0083 15.3 0.6 2.1 2 0 0 2 2 2 1 Pentapeptide repeats (8 copies) TPR_12 PF13424.1 ETO06417.1 - 3.2e-73 241.6 7.9 1.2e-17 63.5 1.2 5.4 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETO06417.1 - 1.8e-42 142.7 33.4 1.7e-11 43.5 0.1 5.5 3 1 3 6 6 6 6 TPR repeat TPR_10 PF13374.1 ETO06417.1 - 8.7e-36 120.8 0.0 3e-05 23.7 0.0 8.6 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETO06417.1 - 6.9e-33 110.9 33.3 1e-06 28.0 1.2 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.12 ETO06417.1 - 1.7e-32 108.6 25.4 8.7e-06 25.2 0.2 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_7 PF13176.1 ETO06417.1 - 4.1e-32 107.4 4.6 0.00016 21.1 0.0 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETO06417.1 - 1.8e-23 80.5 40.7 0.0003 20.3 0.9 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_17 PF13431.1 ETO06417.1 - 2e-11 43.1 9.1 3.1 8.2 0.1 9.5 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO06417.1 - 4.9e-10 39.1 0.0 0.25 12.0 0.0 6.7 6 1 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO06417.1 - 6.2e-09 36.3 0.0 0.16 12.6 0.2 4.7 2 2 3 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO06417.1 - 1.8e-05 24.9 0.0 1.8 8.9 0.1 5.4 5 1 2 7 7 7 1 Tetratricopeptide repeat MIT PF04212.13 ETO06417.1 - 0.00074 19.3 17.1 8 6.4 0.5 7.1 7 0 0 7 7 7 2 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 ETO06417.1 - 0.0013 19.0 3.9 20 5.9 0.0 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat Ten1_2 PF15490.1 ETO06417.1 - 0.03 13.9 0.0 10 5.7 0.0 3.8 2 1 2 4 4 4 0 Telomere-capping, CST complex subunit SHNi-TPR PF10516.4 ETO06417.1 - 0.056 12.7 0.6 34 3.7 0.0 4.4 6 0 0 6 6 6 0 SHNi-TPR Collagen_bind_2 PF12904.2 ETO06417.1 - 0.18 11.6 2.2 5 6.9 0.0 3.2 3 0 0 3 3 3 0 Putative collagen-binding domain of a collagenase TPR_4 PF07721.9 ETO06417.1 - 0.2 12.1 0.0 31 5.3 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat COX15-CtaA PF02628.10 ETO06418.1 - 0.0031 16.4 0.6 0.0051 15.7 0.4 1.3 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Cation_ATPase_C PF00689.16 ETO06418.1 - 0.045 13.2 4.4 0.05 13.1 0.5 2.4 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus Intg_mem_TP0381 PF09529.5 ETO06418.1 - 0.053 12.7 9.2 1.1 8.4 0.2 3.2 3 0 0 3 3 3 0 Integral membrane protein (intg_mem_TP0381) DUF2899 PF11449.3 ETO06418.1 - 0.083 12.0 4.7 0.22 10.6 0.2 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF2899) UPF0104 PF03706.8 ETO06418.1 - 0.1 11.8 2.5 0.18 11.0 1.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) PTR2 PF00854.16 ETO06419.1 - 6.4e-10 38.3 1.1 6.4e-10 38.3 0.8 1.4 2 0 0 2 2 2 1 POT family DUF872 PF05915.7 ETO06419.1 - 0.066 13.0 0.1 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) AAA_12 PF13087.1 ETO06421.1 - 3.4e-63 212.6 0.0 3.4e-63 212.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 ETO06421.1 - 2.7e-17 63.1 3.7 6.2e-17 61.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AF0941-like PF14591.1 ETO06422.1 - 0.015 15.3 1.3 0.019 15.0 0.9 1.2 1 0 0 1 1 1 0 AF0941-like Cation_ATPase_N PF00690.21 ETO06422.1 - 0.023 14.1 0.1 0.052 13.0 0.0 1.6 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus DUF1338 PF07063.8 ETO06422.1 - 0.064 12.3 1.5 0.071 12.1 1.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1338) Ras PF00071.17 ETO06425.1 - 1.4e-14 53.7 0.1 1.2e-13 50.7 0.0 2.2 2 1 1 3 3 3 1 Ras family Miro PF08477.8 ETO06425.1 - 2.5e-05 24.7 0.0 7.4e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein DUF3354 PF11834.3 ETO06426.1 - 0.0031 17.1 0.1 0.0055 16.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3354) DUF4454 PF14628.1 ETO06426.1 - 0.065 12.8 0.0 0.093 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4454) CFIA_Pcf11 PF11526.3 ETO06426.1 - 0.11 12.6 0.5 0.29 11.2 0.0 1.9 2 1 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 Phage_rep_O PF04492.8 ETO06426.1 - 0.56 10.4 2.8 0.39 10.9 0.2 1.9 2 0 0 2 2 2 0 Bacteriophage replication protein O PH PF00169.24 ETO06428.1 - 3.5e-05 23.9 0.8 7.4e-05 22.9 0.6 1.5 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 ETO06428.1 - 0.01 16.0 0.5 0.019 15.1 0.3 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Herpes_UL3 PF03369.8 ETO06428.1 - 0.027 14.4 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL3 protein PH_11 PF15413.1 ETO06428.1 - 0.029 14.6 4.5 0.05 13.8 0.5 2.8 2 1 0 2 2 2 0 Pleckstrin homology domain Ribosomal_S9 PF00380.14 ETO06429.1 - 1.8e-25 89.5 0.0 3.6e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF1083 PF06452.6 ETO06431.1 - 0.0046 16.8 0.2 0.0086 15.9 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1083) SET PF00856.23 ETO06432.1 - 1.5e-08 35.1 0.4 0.00013 22.3 0.1 2.1 2 0 0 2 2 2 2 SET domain DUF912 PF06024.7 ETO06432.1 - 0.0056 16.7 0.3 0.0083 16.1 0.2 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3377 PF11857.3 ETO06432.1 - 0.022 14.3 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DAO PF01266.19 ETO06433.1 - 3.9e-07 29.2 0.0 4.6e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Myco_arth_vir_N PF09610.5 ETO06433.1 - 0.37 10.7 1.8 0.56 10.1 1.3 1.3 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) DAO PF01266.19 ETO06434.1 - 3.6e-32 111.6 0.0 4.1e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 ETO06434.1 - 1.4e-05 24.3 0.0 1.8e-05 23.9 0.0 1.3 1 1 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 ETO06434.1 - 4.9e-05 23.2 0.0 7.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 ETO06434.1 - 0.00058 18.8 0.0 0.0008 18.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 ETO06434.1 - 0.001 18.9 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETO06434.1 - 0.0016 17.3 0.0 0.0022 16.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Mqo PF06039.10 ETO06434.1 - 0.0025 16.0 0.0 0.0033 15.6 0.0 1.1 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) TrkA_N PF02254.13 ETO06434.1 - 0.026 14.5 0.1 0.046 13.7 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.14 ETO06434.1 - 0.027 13.5 0.0 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain K_oxygenase PF13434.1 ETO06434.1 - 0.049 12.5 0.0 0.07 12.0 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 ETO06434.1 - 0.098 12.7 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETO06434.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.9 ETO06434.1 - 0.15 10.5 0.0 0.16 10.3 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein DUF3505 PF12013.3 ETO06436.1 - 0.17 12.0 0.2 0.17 12.0 0.1 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF3505) Protocadherin PF08374.6 ETO06437.1 - 0.26 10.8 3.3 0.32 10.5 2.3 1.2 1 0 0 1 1 1 0 Protocadherin RNA_pol_Rpo13 PF12136.3 ETO06437.1 - 1.2 8.8 5.0 0.41 10.3 0.2 2.2 2 0 0 2 2 2 0 RNA polymerase Rpo13 subunit HTH domain G-alpha PF00503.15 ETO06438.1 - 1.9e-12 46.5 12.5 1.3e-07 30.6 0.3 4.3 3 1 0 3 3 3 2 G-protein alpha subunit Arf PF00025.16 ETO06438.1 - 0.0051 16.0 0.0 0.009 15.2 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family CDC45 PF02724.9 ETO06438.1 - 0.33 8.9 8.0 0.6 8.0 5.6 1.4 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 ETO06438.1 - 1.5 7.9 9.1 3 7.0 6.3 1.4 1 0 0 1 1 1 0 NOA36 protein SSP160 PF06933.6 ETO06438.1 - 2.3 6.1 9.6 3.5 5.4 6.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TRAP_alpha PF03896.11 ETO06438.1 - 6.3 5.7 9.8 14 4.5 6.8 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sulfotransfer_2 PF03567.9 ETO06439.1 - 0.0031 17.2 0.0 0.0038 16.9 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase family Beach PF02138.13 ETO06443.1 - 4.5e-109 364.0 0.2 6.9e-109 363.4 0.1 1.3 1 0 0 1 1 1 1 Beige/BEACH domain FYVE PF01363.16 ETO06443.1 - 3.3e-19 68.5 8.2 3.3e-19 68.5 5.7 1.7 2 0 0 2 2 2 1 FYVE zinc finger WD40 PF00400.27 ETO06443.1 - 1.1e-15 56.7 9.4 1.1e-08 34.6 0.1 4.7 3 1 0 3 3 3 3 WD domain, G-beta repeat IBR PF01485.16 ETO06443.1 - 0.0036 17.1 6.5 0.0036 17.1 4.5 1.9 2 0 0 2 2 2 1 IBR domain FYVE_2 PF02318.11 ETO06443.1 - 0.1 12.4 5.0 0.1 12.5 2.3 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger PH_BEACH PF14844.1 ETO06444.1 - 8.9e-11 41.5 0.6 8.9e-11 41.5 0.4 3.0 3 0 0 3 3 3 1 PH domain associated with Beige/BEACH SpoU_methylase PF00588.14 ETO06445.1 - 0.027 14.3 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 SpoU rRNA Methylase family GrpE PF01025.14 ETO06448.1 - 3.6e-33 114.4 0.1 4e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 GrpE tRNA_edit PF04073.10 ETO06449.1 - 2.4e-32 111.3 0.0 3e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HGTP_anticodon PF03129.15 ETO06449.1 - 0.048 13.5 0.1 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Anticodon binding domain Met_synt_B12 PF02965.12 ETO06449.1 - 0.054 12.6 0.1 0.067 12.3 0.1 1.1 1 0 0 1 1 1 0 Vitamin B12 dependent methionine synthase, activation domain Mito_fiss_Elm1 PF06258.6 ETO06449.1 - 0.067 12.1 0.0 0.093 11.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission ELM1 Lipase_3 PF01764.20 ETO06449.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Phage_CII PF05269.6 ETO06449.1 - 0.11 12.4 0.6 4.6 7.3 0.1 2.7 2 1 1 3 3 3 0 Bacteriophage CII protein DUF3721 PF12518.3 ETO06449.1 - 0.26 10.9 0.8 0.45 10.1 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function Ank_3 PF13606.1 ETO06450.1 - 3.3e-05 23.7 3.6 0.00053 19.9 0.0 3.6 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.2 ETO06450.1 - 0.00013 22.2 0.1 0.0003 21.0 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO06450.1 - 0.00035 21.0 0.3 0.0017 18.8 0.2 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 ETO06450.1 - 0.0075 16.0 5.4 1 9.3 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 ETO06450.1 - 0.36 11.1 3.6 1.8 8.9 0.7 2.9 2 1 1 3 3 3 0 Ankyrin repeats (many copies) PDCD2_C PF04194.8 ETO06451.1 - 0.056 13.0 1.1 0.086 12.4 0.8 1.2 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain AAA_12 PF13087.1 ETO06451.1 - 0.067 12.5 5.7 0.25 10.6 2.3 2.2 1 1 1 2 2 2 0 AAA domain Pilin_PilX PF11530.3 ETO06451.1 - 0.11 12.1 0.6 0.31 10.7 0.1 2.0 2 1 0 2 2 2 0 Minor type IV pilin, PilX DUF3783 PF12646.2 ETO06451.1 - 0.29 10.9 2.0 1.3 8.8 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3783) CTP_transf_2 PF01467.21 ETO06452.1 - 2e-17 63.7 0.7 1e-07 32.1 0.0 2.9 2 2 0 2 2 2 2 Cytidylyltransferase DUF2413 PF10310.4 ETO06452.1 - 0.00015 20.7 8.7 0.00027 19.8 6.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Pox_Ag35 PF03286.9 ETO06452.1 - 0.0032 17.0 11.4 0.0061 16.1 7.9 1.4 1 0 0 1 1 1 1 Pox virus Ag35 surface protein Cellulose_synt PF03552.9 ETO06452.1 - 0.013 13.8 0.8 0.018 13.3 0.6 1.2 1 0 0 1 1 1 0 Cellulose synthase GEMIN8 PF15348.1 ETO06452.1 - 0.071 13.1 10.4 0.081 12.9 3.4 2.8 3 0 0 3 3 3 0 Gemini of Cajal bodies-associated protein 8 BSMAP PF12280.3 ETO06452.1 - 0.13 12.1 5.2 0.27 11.1 3.6 1.4 1 0 0 1 1 1 0 Brain specific membrane anchored protein FAM176 PF14851.1 ETO06452.1 - 0.26 10.9 5.5 0.59 9.8 3.8 1.7 1 0 0 1 1 1 0 FAM176 family DUF3245 PF11595.3 ETO06452.1 - 0.3 11.3 20.0 0.071 13.3 11.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) NARP1 PF12569.3 ETO06452.1 - 0.33 9.6 12.4 0.52 9.0 8.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Zip PF02535.17 ETO06452.1 - 2.2 7.1 6.1 3.4 6.5 2.6 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter Atrophin-1 PF03154.10 ETO06452.1 - 5.1 5.1 7.9 7.4 4.5 5.5 1.1 1 0 0 1 1 1 0 Atrophin-1 family PBP_sp32 PF07222.7 ETO06452.1 - 7 5.7 9.6 14 4.8 6.6 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 RNA_pol_Rpc4 PF05132.9 ETO06452.1 - 8.3 6.4 11.6 18 5.2 8.0 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 zf-CCCH PF00642.19 ETO06453.1 - 9.8e-13 47.4 20.8 4.4e-12 45.3 0.6 3.9 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 ETO06453.1 - 0.00024 20.9 9.2 0.032 14.2 0.9 3.1 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type TPR_12 PF13424.1 ETO06454.1 - 1.1e-24 86.1 1.5 4.5e-15 55.3 0.0 2.4 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO06454.1 - 5.6e-20 70.7 9.4 5.4e-12 45.1 2.4 2.5 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETO06454.1 - 4e-17 61.0 10.4 9.4e-07 28.1 1.5 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO06454.1 - 2.7e-16 58.0 8.3 6.5e-05 22.4 1.6 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO06454.1 - 2.6e-15 54.9 1.0 6.7e-05 22.3 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO06454.1 - 6e-15 53.8 6.1 2.4e-05 23.9 0.6 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO06454.1 - 3e-13 49.2 0.0 5.9e-05 22.8 0.0 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO06454.1 - 2.7e-08 33.3 1.0 0.12 12.6 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO06454.1 - 5.5e-05 23.4 0.1 2.1 9.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO06454.1 - 0.00028 21.1 0.9 0.66 10.5 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO06454.1 - 0.0088 16.6 0.1 0.65 10.7 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat MIT PF04212.13 ETO06454.1 - 0.048 13.5 4.8 8.6 6.3 0.0 3.5 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain PPR PF01535.15 ETO06454.1 - 0.26 11.3 2.5 3.9 7.6 0.0 3.5 4 0 0 4 4 4 0 PPR repeat LRR_1 PF00560.28 ETO06456.1 - 6.5e-08 31.5 32.0 0.079 13.0 0.1 9.3 11 0 0 11 11 11 5 Leucine Rich Repeat LRR_4 PF12799.2 ETO06456.1 - 9.8e-08 31.4 34.8 0.00022 20.7 2.7 6.6 4 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO06456.1 - 1.6e-06 27.7 20.5 0.011 15.4 3.5 5.1 3 1 2 5 5 5 3 Leucine rich repeat FNIP PF05725.7 ETO06456.1 - 0.00013 21.8 0.0 0.48 10.4 0.0 4.8 3 2 0 3 3 3 1 FNIP Repeat LRR_7 PF13504.1 ETO06456.1 - 0.026 14.6 15.4 45 4.8 0.0 6.7 7 0 0 7 7 7 0 Leucine rich repeat LRR_6 PF13516.1 ETO06456.1 - 0.052 13.6 17.5 3.7 7.9 0.1 6.7 5 1 2 7 7 7 0 Leucine Rich repeat DUF3425 PF11905.3 ETO06456.1 - 0.085 12.7 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3425) LRR_4 PF12799.2 ETO06458.1 - 6.3e-10 38.4 16.9 3.1e-05 23.4 0.5 4.5 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETO06458.1 - 3.6e-08 32.3 9.3 4.4 7.7 0.0 6.6 6 1 0 6 6 6 4 Leucine Rich Repeat LRR_8 PF13855.1 ETO06458.1 - 5.2e-07 29.3 12.2 0.00088 18.9 0.3 3.3 2 2 0 2 2 2 2 Leucine rich repeat LRR_7 PF13504.1 ETO06458.1 - 0.00041 20.0 19.1 1.8 9.1 0.1 7.4 8 0 0 8 8 8 3 Leucine rich repeat LRR_6 PF13516.1 ETO06458.1 - 0.048 13.7 25.8 5.4 7.4 0.1 6.9 7 1 1 8 8 8 0 Leucine Rich repeat FAD_binding_4 PF01565.18 ETO06459.1 - 0.0057 16.1 0.0 0.0082 15.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain WD40 PF00400.27 ETO06461.1 - 9.2e-24 82.4 17.9 1.6e-09 37.3 2.2 4.9 5 1 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO06461.1 - 4.6e-06 25.0 3.2 0.00057 18.1 0.8 2.2 1 1 0 2 2 2 2 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO06461.1 - 0.00056 20.2 1.6 0.00056 20.2 1.1 2.6 2 1 0 2 2 2 1 TRAF-type zinc finger DUF342 PF03961.8 ETO06461.1 - 0.36 9.1 13.7 0.5 8.7 9.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) zf-C3HC4_2 PF13923.1 ETO06461.1 - 2 8.5 8.7 0.32 11.0 0.4 3.5 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.15 ETO06461.1 - 8.9 5.9 9.4 0.36 10.3 0.9 2.8 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger FRG PF08867.6 ETO06462.1 - 0.12 12.9 3.0 0.32 11.5 0.1 2.7 3 0 0 3 3 3 0 FRG domain DUF4132 PF13569.1 ETO06463.1 - 0.00077 19.0 0.8 0.0014 18.1 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4132) TraC_F_IV PF11130.3 ETO06463.1 - 0.061 12.7 0.1 0.073 12.4 0.1 1.2 1 0 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer CUE PF02845.11 ETO06464.1 - 0.00077 18.8 1.0 0.0031 16.9 0.0 2.6 3 0 0 3 3 3 1 CUE domain DUF3588 PF12140.3 ETO06464.1 - 0.075 13.1 0.4 0.18 11.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3588) DUF106 PF01956.11 ETO06464.1 - 1.2 8.6 3.5 2.9 7.4 2.4 1.6 1 0 0 1 1 1 0 Integral membrane protein DUF106 Histone_HNS PF00816.16 ETO06464.1 - 1.5 9.3 8.1 1.2 9.6 3.2 2.3 2 0 0 2 2 2 0 H-NS histone family DUF1664 PF07889.7 ETO06464.1 - 6.4 6.5 10.4 0.93 9.2 3.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Asp PF00026.18 ETO06465.1 - 2.5e-37 128.8 0.2 3.2e-37 128.4 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease AzlD PF05437.7 ETO06467.1 - 0.0027 17.6 1.3 0.0081 16.0 0.4 2.2 2 0 0 2 2 2 1 Branched-chain amino acid transport protein (AzlD) Ribosomal_L17 PF01196.14 ETO06468.1 - 0.0062 17.0 0.2 0.01 16.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L17 Cep57_CLD_2 PF14197.1 ETO06468.1 - 0.094 12.6 0.5 0.98 9.4 0.3 2.1 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 BcrAD_BadFG PF01869.15 ETO06468.1 - 0.13 11.5 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family HA2 PF04408.18 ETO06470.1 - 5.2e-15 55.3 3.4 1.4e-13 50.7 0.1 2.5 2 0 0 2 2 2 2 Helicase associated domain (HA2) Helicase_C PF00271.26 ETO06470.1 - 1e-12 47.7 0.0 2.6e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DSX_dimer PF08828.5 ETO06470.1 - 0.12 11.9 1.1 3.8 7.1 0.2 2.5 2 0 0 2 2 2 0 Doublesex dimerisation domain DDHD PF02862.12 ETO06470.1 - 0.82 9.4 6.6 2.1 8.1 4.6 1.6 1 0 0 1 1 1 0 DDHD domain DEAD PF00270.24 ETO06471.1 - 2.2e-07 30.5 0.1 1e-06 28.3 0.1 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 ETO06471.1 - 4.2e-05 23.6 0.1 8.6e-05 22.6 0.0 1.5 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 ETO06471.1 - 0.0016 17.5 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 ETO06471.1 - 0.015 14.6 0.0 0.13 11.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 ETO06471.1 - 0.025 14.1 0.0 0.052 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 ETO06471.1 - 0.028 13.3 0.1 0.055 12.3 0.1 1.5 1 1 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 ETO06471.1 - 0.033 14.4 0.1 0.09 13.0 0.0 1.8 2 0 0 2 2 2 0 ABC transporter AAA_14 PF13173.1 ETO06471.1 - 0.037 13.9 0.0 0.27 11.1 0.0 2.2 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 ETO06471.1 - 0.05 13.0 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.1 ETO06471.1 - 0.062 13.6 0.3 0.062 13.6 0.2 2.0 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.9 ETO06471.1 - 0.1 12.3 0.1 20 4.8 0.0 3.0 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) Miro PF08477.8 ETO06471.1 - 0.11 13.0 0.1 0.25 11.8 0.0 1.9 2 1 0 2 2 2 0 Miro-like protein AAA_33 PF13671.1 ETO06471.1 - 0.13 12.1 0.0 0.29 10.9 0.0 1.8 1 1 1 2 2 2 0 AAA domain GOLGA2L5 PF15070.1 ETO06473.1 - 0.00069 18.2 6.5 0.00081 18.0 4.5 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 OmpH PF03938.9 ETO06473.1 - 0.028 14.3 9.5 0.043 13.7 6.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) bZIP_1 PF00170.16 ETO06473.1 - 0.032 14.1 8.0 0.87 9.5 2.6 2.4 2 0 0 2 2 2 0 bZIP transcription factor DUF553 PF04473.7 ETO06473.1 - 0.065 12.4 1.5 0.089 12.0 1.0 1.2 1 0 0 1 1 1 0 Transglutaminase-like domain V_ATPase_I PF01496.14 ETO06473.1 - 0.067 11.0 4.0 0.073 10.9 2.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GAS PF13851.1 ETO06473.1 - 0.07 12.3 10.2 0.11 11.7 7.0 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Bclt PF15318.1 ETO06473.1 - 0.073 13.0 3.1 0.83 9.6 0.0 2.1 1 1 1 2 2 2 0 Putative Bcl-2 like protein of testis Med11 PF10280.4 ETO06473.1 - 0.094 12.7 6.4 0.14 12.2 4.3 1.4 1 1 0 1 1 1 0 Mediator complex protein Halogen_Hydrol PF10112.4 ETO06473.1 - 0.11 11.9 4.4 0.2 11.0 2.0 1.9 1 1 1 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein CENP-F_leu_zip PF10473.4 ETO06473.1 - 0.16 11.8 9.1 3.5 7.4 2.9 2.2 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF342 PF03961.8 ETO06473.1 - 0.16 10.3 6.5 0.19 10.1 4.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2284 PF10050.4 ETO06473.1 - 0.18 11.4 1.0 0.29 10.7 0.7 1.3 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) Cep57_CLD_2 PF14197.1 ETO06473.1 - 0.21 11.5 8.1 0.83 9.6 0.1 2.5 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 TBPIP PF07106.8 ETO06473.1 - 0.31 10.5 10.0 0.41 10.1 5.6 1.9 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3373 PF11853.3 ETO06473.1 - 0.35 9.3 4.3 0.35 9.3 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Seryl_tRNA_N PF02403.17 ETO06473.1 - 0.38 10.7 6.2 0.69 9.9 4.3 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Phage_GP20 PF06810.6 ETO06473.1 - 0.51 9.7 12.0 3.3 7.1 4.6 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 HALZ PF02183.13 ETO06473.1 - 0.66 9.7 7.2 7.8 6.3 0.5 3.0 2 2 0 2 2 2 0 Homeobox associated leucine zipper IncA PF04156.9 ETO06473.1 - 0.81 9.2 14.9 0.17 11.4 6.3 1.9 1 1 1 2 2 2 0 IncA protein PEP-utilisers_N PF05524.8 ETO06473.1 - 0.9 9.3 4.8 0.68 9.7 1.4 1.9 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal HAUS6_N PF14661.1 ETO06473.1 - 1.1 8.6 10.3 5.1 6.3 3.6 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF3450 PF11932.3 ETO06473.1 - 1.1 8.4 15.6 4.7 6.3 10.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Uds1 PF15456.1 ETO06473.1 - 1.3 8.9 8.1 5.5 7.0 0.0 2.0 1 1 1 2 2 2 0 Up-regulated During Septation Dynamin_N PF00350.18 ETO06473.1 - 1.4 8.7 4.7 2 8.2 3.3 1.5 1 1 0 1 1 1 0 Dynamin family FliD_N PF02465.13 ETO06473.1 - 1.4 9.2 8.7 0.93 9.9 4.4 1.8 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus HR1 PF02185.11 ETO06473.1 - 1.6 8.5 11.6 1.3 8.8 4.9 2.3 1 1 1 2 2 2 0 Hr1 repeat K-box PF01486.12 ETO06473.1 - 1.7 8.4 13.4 2.1 8.2 0.1 2.8 2 1 1 3 3 3 0 K-box region TMF_DNA_bd PF12329.3 ETO06473.1 - 2.2 8.1 10.3 3.5 7.4 4.3 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4446 PF14584.1 ETO06473.1 - 2.5 7.9 6.7 10 5.9 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Prp19 PF08606.6 ETO06473.1 - 3 7.6 8.1 0.81 9.4 2.3 2.1 2 0 0 2 2 2 0 Prp19/Pso4-like AAA_23 PF13476.1 ETO06473.1 - 4.7 7.4 12.2 6.2 7.0 8.4 1.2 1 0 0 1 1 1 0 AAA domain zf-DHHC PF01529.15 ETO06476.1 - 7.3e-33 113.3 18.0 7.3e-33 113.3 12.5 2.4 1 1 1 2 2 2 1 DHHC palmitoyltransferase IMS PF00817.15 ETO06478.1 - 7.3e-21 74.5 0.1 2.3e-20 72.9 0.1 1.9 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 ETO06478.1 - 1e-11 44.8 0.0 3.1e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DNAP_B_exo_N PF08452.5 ETO06478.1 - 0.049 12.8 1.0 0.13 11.5 0.7 1.7 1 0 0 1 1 1 0 DNA polymerase family B exonuclease domain, N-terminal Na_Ca_ex PF01699.19 ETO06479.1 - 4.6e-07 29.5 10.2 1.1e-06 28.2 7.1 1.7 1 1 0 1 1 1 1 Sodium/calcium exchanger protein Ycf15 PF10705.4 ETO06479.1 - 0.025 14.6 0.3 0.052 13.6 0.2 1.5 1 0 0 1 1 1 0 Chloroplast protein precursor Ycf15 putative WD40 PF00400.27 ETO06481.1 - 2.4e-05 24.0 7.7 0.0016 18.2 1.0 3.2 3 1 0 3 3 3 2 WD domain, G-beta repeat Dicty_REP PF05086.7 ETO06482.1 - 0.59 7.8 7.2 0.91 7.2 5.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4199 PF13858.1 ETO06482.1 - 0.82 9.5 5.8 5.4 6.9 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) PSII_Pbs27 PF13326.1 ETO06483.1 - 0.094 12.6 1.1 2.3 8.1 0.0 2.1 2 0 0 2 2 2 0 Photosystem II Pbs27 Atrophin-1 PF03154.10 ETO06483.1 - 6.3 4.8 7.2 7.9 4.4 5.0 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF3582 PF12122.3 ETO06484.1 - 0.0046 16.9 0.9 0.24 11.3 0.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3582) BRCT PF00533.21 ETO06484.1 - 0.022 14.8 0.1 0.038 14.1 0.1 1.5 1 1 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Ribosomal_L5_C PF00673.16 ETO06484.1 - 0.036 13.8 2.1 0.059 13.1 1.5 1.4 1 0 0 1 1 1 0 ribosomal L5P family C-terminus Pur_DNA_glyco PF02245.11 ETO06484.1 - 0.082 12.0 0.2 0.096 11.8 0.1 1.3 1 0 0 1 1 1 0 Methylpurine-DNA glycosylase (MPG) SecY PF00344.15 ETO06485.1 - 1.2e-16 60.5 0.4 1.8e-16 60.0 0.1 1.3 2 0 0 2 2 2 1 SecY translocase Plug_translocon PF10559.4 ETO06485.1 - 1.5e-13 49.9 0.1 5e-13 48.3 0.0 1.8 2 0 0 2 2 2 1 Plug domain of Sec61p DUF1947 PF09183.5 ETO06486.1 - 0.034 13.8 0.1 0.23 11.2 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1947) Peptidase_S49_N PF08496.5 ETO06488.1 - 0.15 11.8 2.5 0.16 11.7 1.7 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DDRGK PF09756.4 ETO06489.1 - 4 6.8 41.6 4 6.7 28.9 1.0 1 0 0 1 1 1 0 DDRGK domain Spore_coat_CotO PF14153.1 ETO06489.1 - 8.6 5.7 27.9 9.4 5.6 19.4 1.0 1 0 0 1 1 1 0 Spore coat protein CotO DUF3810 PF12725.2 ETO06494.1 - 0.024 13.5 2.4 0.026 13.4 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) NikR_C PF08753.6 ETO06494.1 - 0.025 14.4 0.8 3.2 7.7 0.2 2.3 2 0 0 2 2 2 0 NikR C terminal nickel binding domain FlaC_arch PF05377.6 ETO06494.1 - 0.11 12.4 0.3 0.11 12.4 0.2 2.3 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF737 PF05300.6 ETO06494.1 - 0.25 11.2 6.6 0.32 10.9 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) HALZ PF02183.13 ETO06494.1 - 0.9 9.3 11.7 2.8 7.7 2.6 3.0 2 1 1 3 3 3 0 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.7 ETO06494.1 - 1 9.0 13.2 4.8 6.9 9.1 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein HAUS-augmin3 PF14932.1 ETO06494.1 - 1.2 8.2 12.4 1.5 7.9 8.6 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Orthopox_A5L PF06193.6 ETO06494.1 - 1.4 8.8 6.2 5.7 6.8 0.5 2.0 1 1 1 2 2 2 0 Orthopoxvirus A5L protein-like bZIP_1 PF00170.16 ETO06494.1 - 1.8 8.5 14.4 0.84 9.6 4.2 2.5 1 1 2 3 3 3 0 bZIP transcription factor Prefoldin_2 PF01920.15 ETO06494.1 - 2.4 7.9 13.6 4.6 7.0 1.0 2.0 2 0 0 2 2 2 0 Prefoldin subunit PspA_IM30 PF04012.7 ETO06494.1 - 2.5 7.4 12.6 92 2.2 8.7 2.0 1 1 0 1 1 1 0 PspA/IM30 family GED PF02212.13 ETO06494.1 - 2.8 7.8 6.7 1.3 8.9 1.7 2.0 2 0 0 2 2 2 0 Dynamin GTPase effector domain ADIP PF11559.3 ETO06494.1 - 4.8 7.0 14.1 3.9 7.3 1.5 2.1 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding bZIP_2 PF07716.10 ETO06494.1 - 7.8 6.4 17.3 5.3 6.9 1.9 2.6 2 1 0 2 2 2 0 Basic region leucine zipper PCRF PF03462.13 ETO06494.1 - 9.5 5.9 8.4 4.6 6.9 1.9 2.0 1 1 1 2 2 2 0 PCRF domain DUF919 PF06034.6 ETO06495.1 - 0.2 11.2 13.4 0.43 10.2 9.3 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DUF775 PF05603.7 ETO06495.1 - 0.66 9.4 8.3 0.81 9.1 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF4647 PF15504.1 ETO06495.1 - 1.3 7.8 15.7 1.4 7.7 10.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) SR-25 PF10500.4 ETO06495.1 - 1.3 8.4 8.7 1.5 8.1 6.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IncA PF04156.9 ETO06495.1 - 1.7 8.2 11.7 2.2 7.8 8.1 1.2 1 0 0 1 1 1 0 IncA protein Phlebovirus_NSM PF07246.6 ETO06495.1 - 5.3 6.1 11.3 6 5.9 7.9 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Mit_KHE1 PF10173.4 ETO06495.1 - 5.8 6.7 8.1 6.7 6.5 5.6 1.1 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related ERM PF00769.14 ETO06495.1 - 6.1 6.3 19.5 7.2 6.0 13.5 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Rsc14 PF08586.5 ETO06495.1 - 6.5 7.2 9.0 3.2 8.2 4.2 1.7 1 1 1 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit Exonuc_VII_L PF02601.10 ETO06495.1 - 8.1 5.5 15.0 10 5.1 10.4 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Raftlin PF15250.1 ETO06496.1 - 0.53 8.7 8.7 0.65 8.4 6.0 1.1 1 0 0 1 1 1 0 Raftlin DUF572 PF04502.8 ETO06496.1 - 0.63 9.1 17.9 0.71 9.0 12.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) AUX_IAA PF02309.11 ETO06496.1 - 0.71 9.5 12.5 0.92 9.2 8.6 1.2 1 0 0 1 1 1 0 AUX/IAA family Herpes_BLLF1 PF05109.8 ETO06496.1 - 0.94 7.3 7.5 1.1 7.1 5.2 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) SRP-alpha_N PF04086.8 ETO06496.1 - 1.1 8.6 20.9 1.4 8.2 14.5 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal YL1 PF05764.8 ETO06496.1 - 1.2 8.6 26.2 1.5 8.3 18.2 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Macoilin PF09726.4 ETO06496.1 - 1.3 7.2 13.4 1.4 7.0 9.3 1.0 1 0 0 1 1 1 0 Transmembrane protein DNA_pol_viral_N PF00242.12 ETO06496.1 - 1.3 7.9 14.1 1.5 7.7 9.7 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain RR_TM4-6 PF06459.7 ETO06496.1 - 1.4 8.7 11.0 1.7 8.4 7.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF966 PF06136.8 ETO06496.1 - 2 7.7 21.0 2.6 7.4 14.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF2413 PF10310.4 ETO06496.1 - 2.9 6.5 16.7 3.6 6.2 11.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Ndc1_Nup PF09531.5 ETO06496.1 - 3.4 5.9 15.5 4.1 5.7 10.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2201_N PF13203.1 ETO06496.1 - 5.2 6.1 9.8 6.2 5.8 6.8 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Borrelia_P83 PF05262.6 ETO06496.1 - 6.3 4.9 16.5 7.1 4.7 11.5 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF566 PF04484.7 ETO06496.1 - 8.6 5.7 20.4 11 5.4 14.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF4554 PF15091.1 ETO06496.1 - 9.7 4.7 11.8 12 4.4 8.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) MFS_1 PF07690.11 ETO06497.1 - 2.7e-10 39.4 0.4 3.7e-10 39.0 0.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily FA_desaturase PF00487.19 ETO06497.1 - 0.013 14.9 0.0 0.045 13.2 0.0 1.7 2 0 0 2 2 2 0 Fatty acid desaturase ATP-synt_8 PF00895.15 ETO06497.1 - 0.086 13.0 0.3 0.33 11.1 0.0 2.1 1 1 1 2 2 2 0 ATP synthase protein 8 PITH PF06201.8 ETO06498.1 - 2e-14 53.6 4.3 3.4e-14 52.8 2.5 1.8 1 1 0 1 1 1 1 PITH domain BTV_NS2 PF04514.7 ETO06498.1 - 0.016 14.1 2.6 0.018 13.9 1.8 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Nucleoplasmin PF03066.10 ETO06498.1 - 0.02 14.4 4.1 0.041 13.3 2.8 1.7 1 0 0 1 1 1 0 Nucleoplasmin FAM176 PF14851.1 ETO06498.1 - 0.021 14.4 1.8 0.04 13.6 1.2 1.5 1 0 0 1 1 1 0 FAM176 family LAT PF15234.1 ETO06498.1 - 0.075 12.4 1.2 0.1 12.0 0.8 1.3 1 0 0 1 1 1 0 Linker for activation of T-cells CENP-B_dimeris PF09026.5 ETO06498.1 - 0.079 13.2 6.5 0.15 12.3 4.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 ETO06498.1 - 1.9 8.8 7.7 3.9 7.8 5.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Vps52 PF04129.7 ETO06499.1 - 9.5e-21 73.8 0.4 9.5e-21 73.8 0.2 1.5 2 0 0 2 2 2 1 Vps52 / Sac2 family PHTB1_C PF14728.1 ETO06499.1 - 0.00019 20.3 3.6 0.14 10.9 0.4 2.1 1 1 1 2 2 2 2 PTHB1 C-terminus Hormone_recep PF00104.25 ETO06499.1 - 0.0031 16.6 0.8 0.049 12.7 0.5 2.2 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DASH_Spc19 PF08287.6 ETO06499.1 - 0.0048 16.5 0.6 0.011 15.3 0.1 1.8 2 0 0 2 2 2 1 Spc19 Thy1 PF02511.10 ETO06499.1 - 0.074 12.4 0.6 0.49 9.7 0.1 2.2 2 1 0 2 2 2 0 Thymidylate synthase complementing protein TPR_15 PF13429.1 ETO06500.1 - 0.044 12.8 1.1 0.075 12.0 0.5 1.4 1 1 0 1 1 1 0 Tetratricopeptide repeat DUF1088 PF06469.6 ETO06500.1 - 0.045 13.1 0.3 0.051 12.9 0.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1088) HSP70 PF00012.15 ETO06501.1 - 5.6e-136 453.8 7.1 4.9e-104 348.3 1.6 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 ETO06501.1 - 1.3e-07 30.5 0.2 0.0019 16.8 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DDR PF08841.5 ETO06501.1 - 0.029 13.1 0.0 2.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain PA28_alpha PF02251.13 ETO06501.1 - 0.048 13.8 0.2 0.11 12.6 0.2 1.6 1 0 0 1 1 1 0 Proteasome activator pa28 alpha subunit Spt5_N PF11942.3 ETO06502.1 - 1.7 9.3 8.9 3.5 8.3 6.2 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF3529 PF12046.3 ETO06503.1 - 0.072 12.1 0.2 0.25 10.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3529) FAD_binding_3 PF01494.14 ETO06504.1 - 0.00079 18.5 0.0 0.022 13.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Viral_Beta_CD PF04530.7 ETO06505.1 - 2.8 8.1 6.1 0.28 11.3 0.5 2.2 2 1 0 2 2 2 0 Viral Beta C/D like family AAA PF00004.24 ETO06506.1 - 1.4e-17 64.1 0.0 8.2e-17 61.6 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 ETO06506.1 - 3.3e-08 33.4 0.1 3.3e-08 33.4 0.1 2.2 2 1 0 2 2 1 1 ATP-dependent protease La (LON) domain AAA_22 PF13401.1 ETO06506.1 - 9.6e-07 29.0 0.0 6e-06 26.4 0.0 2.4 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 ETO06506.1 - 4.6e-05 23.4 3.1 8e-05 22.6 0.0 2.8 4 0 0 4 4 3 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 ETO06506.1 - 9.2e-05 22.1 0.4 0.00033 20.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 ETO06506.1 - 0.00032 21.4 0.3 0.01 16.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 ETO06506.1 - 0.00034 20.6 1.9 0.0021 18.0 0.1 3.0 3 2 0 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 ETO06506.1 - 0.0007 19.4 0.0 0.0026 17.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 ETO06506.1 - 0.0012 19.0 1.6 0.077 13.1 0.0 3.8 4 0 0 4 4 4 1 RNA helicase SR-25 PF10500.4 ETO06506.1 - 0.0022 17.5 11.2 0.0022 17.5 7.8 2.3 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein NTPase_1 PF03266.10 ETO06506.1 - 0.0027 17.4 0.0 1.2 8.8 0.0 3.2 3 0 0 3 3 3 1 NTPase IstB_IS21 PF01695.12 ETO06506.1 - 0.0089 15.4 0.0 0.033 13.5 0.0 2.1 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.6 ETO06506.1 - 0.011 15.3 0.0 0.031 13.8 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 ETO06506.1 - 0.014 14.1 0.8 0.032 12.9 0.0 1.9 2 0 0 2 2 2 0 TIP49 C-terminus AAA_24 PF13479.1 ETO06506.1 - 0.015 14.9 0.5 0.29 10.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 ETO06506.1 - 0.018 15.3 0.1 0.018 15.3 0.0 2.9 4 0 0 4 4 2 0 AAA domain DUF3025 PF11227.3 ETO06506.1 - 0.042 13.3 0.2 0.078 12.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) CENP-X PF09415.5 ETO06506.1 - 0.046 13.5 0.5 4.7 7.0 0.0 3.2 3 0 0 3 3 3 0 CENP-S associating Centromere protein X AAA_25 PF13481.1 ETO06506.1 - 0.066 12.6 0.0 0.27 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 ETO06506.1 - 0.071 12.8 0.0 0.22 11.2 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ArsA_ATPase PF02374.10 ETO06506.1 - 0.077 12.0 4.9 1.9 7.4 0.0 3.0 3 0 0 3 3 3 0 Anion-transporting ATPase RuvB_N PF05496.7 ETO06506.1 - 0.092 11.7 0.2 0.25 10.3 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus SKI PF01202.17 ETO06506.1 - 0.13 12.1 0.0 0.13 12.1 0.0 2.8 3 1 1 4 4 3 0 Shikimate kinase AAA_19 PF13245.1 ETO06506.1 - 0.16 11.7 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 ETO06506.1 - 0.24 11.2 1.6 0.62 9.9 0.0 2.5 3 1 0 3 3 2 0 AAA domain Amidase PF01425.16 ETO06506.1 - 0.28 10.0 2.1 0.27 10.0 0.8 1.5 1 1 0 1 1 1 0 Amidase Type_III_YscX PF09474.5 ETO06506.1 - 0.64 10.0 5.8 0.53 10.3 0.4 2.8 2 1 0 3 3 3 0 Type III secretion system YscX (type_III_YscX) Secretin_N_2 PF07655.8 ETO06506.1 - 2.2 8.7 27.2 0.076 13.4 5.2 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain BLOC1_2 PF10046.4 ETO06507.1 - 0.0025 17.9 20.6 0.0078 16.3 6.7 3.6 1 1 2 3 3 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4201 PF13870.1 ETO06507.1 - 0.0052 16.2 36.4 0.22 10.9 10.7 3.0 1 1 2 3 3 3 3 Domain of unknown function (DUF4201) Tropomyosin_1 PF12718.2 ETO06507.1 - 0.0056 16.5 14.0 0.0056 16.5 9.7 2.9 1 1 2 3 3 3 2 Tropomyosin like GAS PF13851.1 ETO06507.1 - 0.0089 15.2 35.7 0.26 10.4 13.8 2.5 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding AAA_27 PF13514.1 ETO06507.1 - 0.015 13.0 19.1 0.043 11.4 13.2 1.6 1 1 0 1 1 1 0 AAA domain ABC_membrane_2 PF06472.10 ETO06507.1 - 0.046 12.8 1.7 0.068 12.2 0.8 1.5 1 1 0 1 1 1 0 ABC transporter transmembrane region 2 Lipocalin_2 PF08212.7 ETO06507.1 - 0.053 13.2 3.3 1.7 8.3 0.2 2.3 2 0 0 2 2 2 0 Lipocalin-like domain Reo_sigmaC PF04582.7 ETO06507.1 - 0.062 12.4 4.7 0.045 12.9 1.5 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Spectrin PF00435.16 ETO06507.1 - 0.08 13.2 27.0 0.046 14.0 8.1 3.0 2 1 1 3 3 3 0 Spectrin repeat NPV_P10 PF05531.7 ETO06507.1 - 0.094 12.9 15.5 0.13 12.4 0.1 3.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 ETO06507.1 - 0.2 11.2 35.3 1.5 8.3 4.8 3.0 1 1 1 2 2 2 0 IncA protein HAP1_N PF04849.8 ETO06507.1 - 0.26 10.1 37.8 0.097 11.5 12.1 2.3 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Uds1 PF15456.1 ETO06507.1 - 0.36 10.8 22.0 6.5 6.7 0.2 3.3 1 1 1 2 2 2 0 Up-regulated During Septation HrpB7 PF09486.5 ETO06507.1 - 0.42 10.5 10.2 0.13 12.1 4.5 2.0 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DivIVA PF05103.8 ETO06507.1 - 0.68 9.9 28.5 0.46 10.5 10.6 3.8 1 1 2 3 3 3 0 DivIVA protein DivIC PF04977.10 ETO06507.1 - 0.73 9.3 32.3 0.24 10.9 2.3 4.5 1 1 3 4 4 4 0 Septum formation initiator ADIP PF11559.3 ETO06507.1 - 0.81 9.5 35.5 0.19 11.6 7.0 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 ETO06507.1 - 0.9 8.5 33.3 2.9 6.8 11.6 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF812 PF05667.6 ETO06507.1 - 0.93 7.9 27.5 1.2 7.5 19.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Tropomyosin PF00261.15 ETO06507.1 - 1 8.4 26.6 1.4 7.9 0.9 3.0 1 1 1 2 2 2 0 Tropomyosin WXG100 PF06013.7 ETO06507.1 - 1.5 8.8 14.1 6.7 6.7 0.1 3.8 1 1 3 4 4 4 0 Proteins of 100 residues with WXG DUF948 PF06103.6 ETO06507.1 - 1.7 8.5 18.4 0.034 14.0 2.7 3.1 1 1 1 2 2 1 0 Bacterial protein of unknown function (DUF948) DUF4140 PF13600.1 ETO06507.1 - 2.2 8.7 14.8 5.6 7.4 0.2 3.8 1 1 3 4 4 4 0 N-terminal domain of unknown function (DUF4140) CENP-F_leu_zip PF10473.4 ETO06507.1 - 2.3 8.0 34.4 1.4 8.7 15.4 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N PF09744.4 ETO06507.1 - 2.4 8.1 31.7 2.1 8.3 0.7 3.1 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 V_ATPase_I PF01496.14 ETO06507.1 - 3.4 5.4 21.7 3.5 5.3 10.3 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF869 PF05911.6 ETO06507.1 - 3.5 5.7 27.8 6.7 4.8 19.2 1.4 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) DUF904 PF06005.7 ETO06507.1 - 4.5 7.6 37.7 2.4 8.4 4.6 4.2 1 1 3 4 4 4 0 Protein of unknown function (DUF904) Rootletin PF15035.1 ETO06507.1 - 4.7 7.1 33.3 1.9 8.4 15.0 3.0 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion DUF4349 PF14257.1 ETO06507.1 - 5.1 6.2 9.2 2.9 7.0 0.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4349) Phage_GP20 PF06810.6 ETO06507.1 - 5.3 6.4 32.9 0.056 12.8 7.3 3.0 1 1 2 3 3 2 0 Phage minor structural protein GP20 T2SM PF04612.7 ETO06507.1 - 5.5 6.7 8.9 21 4.8 2.8 2.8 1 1 2 3 3 3 0 Type II secretion system (T2SS), protein M Atg14 PF10186.4 ETO06507.1 - 7.5 5.4 30.3 0.073 12.0 6.1 3.0 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Seryl_tRNA_N PF02403.17 ETO06507.1 - 9.1 6.3 23.3 0.25 11.3 1.2 3.0 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Osmo_CC PF08946.5 ETO06507.1 - 9.5 6.3 12.6 0.2 11.6 0.9 3.2 3 1 0 3 3 2 0 Osmosensory transporter coiled coil ATP-synt_ab PF00006.20 ETO06508.1 - 2.4e-106 354.0 0.0 4.3e-106 353.2 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 ETO06508.1 - 1.4e-22 80.2 0.9 3.1e-22 79.1 0.6 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 ETO06508.1 - 1.8e-08 34.4 0.4 1.8e-08 34.4 0.3 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain Mob_Pre PF01076.14 ETO06508.1 - 0.023 14.3 0.3 0.058 13.0 0.2 1.6 1 0 0 1 1 1 0 Plasmid recombination enzyme AAA_16 PF13191.1 ETO06508.1 - 0.21 11.5 0.1 2.5 8.0 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain MCRS_N PF13325.1 ETO06509.1 - 0.13 11.7 6.1 0.088 12.3 2.8 1.8 1 1 0 2 2 2 0 N-terminal region of micro-spherule protein Myc_N PF01056.13 ETO06509.1 - 0.18 10.9 6.3 0.21 10.7 4.4 1.3 1 0 0 1 1 1 0 Myc amino-terminal region DUF2146 PF10220.4 ETO06509.1 - 0.24 9.3 7.3 0.32 8.9 5.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) CDC45 PF02724.9 ETO06509.1 - 0.78 7.6 8.9 1.1 7.2 6.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid PF03115.9 ETO06509.1 - 0.8 7.8 5.4 0.86 7.7 3.8 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor CENP-B_dimeris PF09026.5 ETO06509.1 - 1.2 9.4 10.9 2.7 8.2 7.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF506 PF04720.7 ETO06509.1 - 1.3 8.6 6.4 2 7.9 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Nop14 PF04147.7 ETO06509.1 - 2.4 5.9 15.9 3.3 5.4 11.0 1.1 1 0 0 1 1 1 0 Nop14-like family Bap31 PF05529.7 ETO06509.1 - 2.8 7.3 7.7 0.9 8.9 2.5 2.0 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like PIP5K PF01504.13 ETO06510.1 - 2.3e-24 85.8 1.5 6.7e-23 81.0 1.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Phage_GP20 PF06810.6 ETO06511.1 - 0.0096 15.3 5.3 0.0096 15.3 3.7 1.9 1 1 1 2 2 2 1 Phage minor structural protein GP20 Pepsin-I3 PF06394.8 ETO06511.1 - 0.096 12.3 4.6 0.062 12.9 1.8 1.7 1 1 1 2 2 2 0 Pepsin inhibitor-3-like repeated domain AKNA PF12443.3 ETO06511.1 - 0.58 10.2 4.7 0.81 9.7 3.0 1.4 1 1 0 1 1 1 0 AT-hook-containing transcription factor DUF1312 PF07009.6 ETO06511.1 - 0.69 9.7 5.3 0.38 10.5 2.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1312) WD40 PF00400.27 ETO06512.1 - 6.1e-24 82.9 3.2 2.2e-10 40.0 0.0 3.6 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO06512.1 - 0.024 12.7 0.0 0.28 9.2 0.0 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 GshA PF08886.6 ETO06512.1 - 0.068 11.4 0.1 0.1 10.8 0.1 1.2 1 0 0 1 1 1 0 Glutamate-cysteine ligase Nucleoporin_N PF08801.6 ETO06512.1 - 0.49 9.0 3.8 4.7 5.8 0.0 2.1 1 1 0 2 2 2 0 Nup133 N terminal like HALZ PF02183.13 ETO06513.1 - 0.0011 18.5 14.8 0.0071 16.0 0.8 3.4 3 0 0 3 3 3 2 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.7 ETO06513.1 - 0.0021 17.7 10.4 0.0021 17.7 7.2 3.1 3 0 0 3 3 3 1 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 ETO06513.1 - 0.0039 17.0 8.1 0.0039 17.0 5.6 3.0 3 1 0 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YqgF PF14639.1 ETO06513.1 - 0.0097 15.4 1.7 0.032 13.8 0.0 2.3 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 GAS PF13851.1 ETO06513.1 - 0.01 15.0 27.3 0.47 9.6 7.2 3.1 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding WEMBL PF05701.6 ETO06513.1 - 0.028 12.9 21.3 0.028 12.8 3.7 3.2 3 1 0 3 3 3 0 Weak chloroplast movement under blue light DUF1053 PF06327.9 ETO06513.1 - 0.065 13.5 11.1 0.32 11.3 2.4 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) ERM PF00769.14 ETO06513.1 - 0.3 10.5 27.0 0.054 13.0 5.9 2.6 3 0 0 3 3 3 0 Ezrin/radixin/moesin family Tropomyosin_1 PF12718.2 ETO06513.1 - 0.77 9.6 28.5 0.15 11.9 6.4 2.8 3 0 0 3 3 2 0 Tropomyosin like Sec34 PF04136.10 ETO06513.1 - 0.8 9.3 13.5 2.5 7.7 2.2 2.8 3 0 0 3 3 3 0 Sec34-like family IncA PF04156.9 ETO06513.1 - 1.2 8.7 29.2 0.11 12.0 6.7 3.3 2 1 0 3 3 3 0 IncA protein ADIP PF11559.3 ETO06513.1 - 1.2 8.9 22.1 0.38 10.6 4.5 3.2 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 ETO06513.1 - 1.7 9.0 22.3 2.3 8.6 4.3 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF972) Fez1 PF06818.10 ETO06513.1 - 1.8 8.5 17.7 0.51 10.3 4.3 3.0 3 1 0 3 3 3 0 Fez1 Acetyltransf_11 PF13720.1 ETO06513.1 - 2.5 8.3 5.4 2.2 8.5 0.4 3.0 3 2 1 4 4 4 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 BLOC1_2 PF10046.4 ETO06513.1 - 3 8.0 19.5 1.8 8.7 2.5 4.0 2 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4201 PF13870.1 ETO06513.1 - 4.9 6.5 25.7 0.82 9.0 5.6 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4201) KSR1-SAM PF13543.1 ETO06513.1 - 6.4 6.5 9.4 0.5 10.1 0.1 2.9 2 1 2 4 4 4 0 SAM like domain present in kinase suppressor RAS 1 BING4CT PF08149.6 ETO06513.1 - 8.2 6.0 6.5 1.6 8.2 0.0 2.9 3 0 0 3 3 3 0 BING4CT (NUC141) domain NAAA-beta PF15508.1 ETO06514.1 - 3.4e-07 30.5 0.0 5e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase AAT PF03417.11 ETO06515.1 - 1.8e-05 24.3 0.0 0.0025 17.3 0.0 2.1 1 1 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase DDHD PF02862.12 ETO06516.1 - 1.2 8.8 6.0 1.9 8.2 4.1 1.4 1 0 0 1 1 1 0 DDHD domain Ycf1 PF05758.7 ETO06516.1 - 2.2 5.8 13.4 2.6 5.6 9.3 1.0 1 0 0 1 1 1 0 Ycf1 Vfa1 PF08432.5 ETO06516.1 - 2.9 7.8 14.6 4.1 7.4 10.1 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3807 PF12720.2 ETO06516.1 - 8.9 6.4 15.9 12 6.0 11.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) zf-DNA_Pol PF08996.5 ETO06517.1 - 0.15 11.4 3.1 0.49 9.7 0.1 2.1 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger ERp29 PF07749.7 ETO06517.1 - 2.9 8.5 5.5 1.8 9.2 2.1 1.8 2 0 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain DivIC PF04977.10 ETO06518.1 - 0.042 13.3 2.9 2.5 7.6 0.6 2.3 2 0 0 2 2 2 0 Septum formation initiator Herpes_glycop PF01528.11 ETO06518.1 - 0.088 11.4 0.2 0.11 11.1 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein M DAGAT PF03982.8 ETO06520.1 - 9.5e-21 73.7 0.3 1.3e-20 73.2 0.2 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase FmrO PF07091.6 ETO06520.1 - 0.075 12.0 0.1 0.12 11.3 0.1 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Oest_recep PF02159.10 ETO06521.1 - 0.069 13.2 1.6 0.55 10.3 0.1 2.2 2 0 0 2 2 2 0 Oestrogen receptor Arm PF00514.18 ETO06523.1 - 9.2e-07 28.4 1.5 0.0072 16.1 0.0 2.7 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat IBB PF01749.15 ETO06523.1 - 1.4e-05 25.1 6.0 2.7e-05 24.2 4.1 1.6 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 ETO06523.1 - 0.12 12.8 0.0 0.31 11.6 0.0 1.7 1 0 0 1 1 1 0 HEAT-like repeat Nop25 PF09805.4 ETO06523.1 - 0.22 11.5 7.3 0.41 10.7 5.1 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Macoilin PF09726.4 ETO06524.1 - 0.004 15.5 8.7 0.0046 15.3 6.0 1.1 1 0 0 1 1 1 1 Transmembrane protein Utp14 PF04615.8 ETO06524.1 - 7.8 4.5 11.0 11 4.0 7.6 1.1 1 0 0 1 1 1 0 Utp14 protein AKAP7_NLS PF10469.4 ETO06525.1 - 0.029 14.0 1.3 0.046 13.4 0.9 1.3 1 0 0 1 1 1 0 AKAP7 2'5' RNA ligase-like domain Tom37_C PF11801.3 ETO06525.1 - 0.91 9.3 4.8 1.3 8.8 3.2 1.3 1 1 0 1 1 1 0 Tom37 C-terminal domain PKD_channel PF08016.7 ETO06527.1 - 4.2e-10 38.6 0.9 5.9e-10 38.1 0.6 1.1 1 0 0 1 1 1 1 Polycystin cation channel Pkinase PF00069.20 ETO06528.1 - 8.7e-33 113.5 0.0 2.2e-32 112.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO06528.1 - 1.5e-12 47.1 0.0 2.7e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 ETO06528.1 - 0.00024 20.7 0.3 0.00066 19.3 0.1 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kinase-like PF14531.1 ETO06528.1 - 0.0026 16.7 0.0 0.005 15.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETO06528.1 - 0.0085 15.1 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO06528.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Zn_ribbon_recom PF13408.1 ETO06528.1 - 0.12 12.5 0.1 0.36 11.1 0.1 1.7 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Telomerase_RBD PF12009.3 ETO06529.1 - 2.4e-12 46.9 2.1 5.3e-12 45.8 1.5 1.6 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 ETO06529.1 - 0.0023 17.3 0.3 0.024 14.0 0.2 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Flavi_capsid PF01003.14 ETO06530.1 - 0.54 9.8 7.5 1.5 8.4 0.1 2.6 3 0 0 3 3 3 0 Flavivirus capsid protein C Cob_adeno_trans PF01923.13 ETO06531.1 - 0.0035 17.1 0.8 0.0058 16.4 0.5 1.4 1 0 0 1 1 1 1 Cobalamin adenosyltransferase WD40 PF00400.27 ETO06532.1 - 4e-49 162.8 20.0 2e-09 36.9 0.2 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO06532.1 - 4.4e-08 31.7 1.2 0.0013 16.9 0.0 3.8 2 1 1 3 3 3 3 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO06532.1 - 0.0008 19.7 9.3 0.0008 19.7 6.5 2.6 1 1 1 2 2 2 1 TRAF-type zinc finger DUF972 PF06156.8 ETO06532.1 - 0.00095 19.4 19.5 0.002 18.4 3.4 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF972) HALZ PF02183.13 ETO06532.1 - 0.0038 16.9 7.8 0.37 10.5 2.4 2.6 2 0 0 2 2 2 2 Homeobox associated leucine zipper bZIP_1 PF00170.16 ETO06532.1 - 0.14 12.1 12.5 0.22 11.4 0.7 3.1 2 1 1 3 3 3 0 bZIP transcription factor DivIC PF04977.10 ETO06532.1 - 0.21 11.0 11.6 0.27 10.7 0.6 3.0 2 1 0 2 2 2 0 Septum formation initiator DUF904 PF06005.7 ETO06532.1 - 0.35 11.2 19.6 0.44 10.8 5.4 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF904) 7tm_2 PF00002.19 ETO06533.1 - 0.16 11.0 1.5 2 7.4 0.0 2.0 2 0 0 2 2 2 0 7 transmembrane receptor (Secretin family) BTV_NS2 PF04514.7 ETO06534.1 - 0.36 9.6 10.6 0.43 9.3 7.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Zip PF02535.17 ETO06534.1 - 0.65 8.9 3.9 0.78 8.6 2.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter G-alpha PF00503.15 ETO06535.1 - 0.00046 19.0 0.0 0.00046 19.0 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Spore_coat_CotO PF14153.1 ETO06536.1 - 0.0084 15.5 7.7 0.0094 15.4 5.4 1.2 1 0 0 1 1 1 1 Spore coat protein CotO Borrelia_P83 PF05262.6 ETO06536.1 - 0.014 13.7 8.8 0.015 13.5 6.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein HSP90 PF00183.13 ETO06536.1 - 0.042 12.2 7.4 0.048 12.0 5.2 1.1 1 0 0 1 1 1 0 Hsp90 protein Ycf1 PF05758.7 ETO06536.1 - 0.094 10.4 4.7 0.086 10.5 3.3 1.0 1 0 0 1 1 1 0 Ycf1 Pal1 PF08316.6 ETO06536.1 - 0.11 12.9 4.7 0.18 12.2 2.6 1.9 2 0 0 2 2 2 0 Pal1 cell morphology protein Daxx PF03344.10 ETO06536.1 - 0.12 10.8 10.0 0.12 10.8 6.9 1.1 1 0 0 1 1 1 0 Daxx Family TORC_M PF12885.2 ETO06536.1 - 0.22 11.2 1.7 0.45 10.2 1.2 1.6 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain CDC45 PF02724.9 ETO06536.1 - 0.34 8.8 6.9 0.32 8.9 4.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Senescence_reg PF04520.8 ETO06536.1 - 0.74 10.3 8.8 0.32 11.4 3.9 1.9 2 0 0 2 2 2 0 Senescence regulator DUF1510 PF07423.6 ETO06536.1 - 2.2 7.6 17.3 3.7 6.8 12.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Tim54 PF11711.3 ETO06536.1 - 2.2 6.7 10.3 0.49 8.9 5.0 1.4 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 YqfQ PF14181.1 ETO06536.1 - 5.8 6.9 12.9 5.8 6.9 8.0 1.7 2 0 0 2 2 2 0 YqfQ-like protein Hid1 PF12722.2 ETO06536.1 - 8.1 3.9 6.8 9.4 3.7 4.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4407 PF14362.1 ETO06536.1 - 9.4 5.0 8.2 15 4.4 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF912 PF06024.7 ETO06541.1 - 2e-05 24.5 7.9 2.6e-05 24.2 5.5 1.0 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Ctr PF04145.10 ETO06541.1 - 0.01 15.8 0.2 0.012 15.6 0.1 1.0 1 0 0 1 1 1 0 Ctr copper transporter family HCO3_cotransp PF00955.16 ETO06541.1 - 0.015 13.9 0.4 0.016 13.8 0.3 1.0 1 0 0 1 1 1 0 HCO3- transporter family BatD PF13584.1 ETO06541.1 - 0.017 13.7 1.0 0.019 13.5 0.7 1.0 1 0 0 1 1 1 0 Oxygen tolerance Pex14_N PF04695.8 ETO06541.1 - 0.021 14.9 0.4 0.023 14.7 0.3 1.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Fig1 PF12351.3 ETO06541.1 - 0.028 14.3 0.1 0.032 14.1 0.1 1.0 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 Claudin_2 PF13903.1 ETO06541.1 - 0.039 13.6 0.6 0.047 13.3 0.4 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction ABC2_membrane_3 PF12698.2 ETO06541.1 - 0.45 9.5 7.2 0.52 9.2 5.0 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1390 PF07150.6 ETO06541.1 - 0.86 8.9 11.1 0.99 8.7 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) DUF3753 PF12575.3 ETO06541.1 - 1.3 8.8 7.2 0.78 9.5 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3753) ETRAMP PF09716.5 ETO06541.1 - 3.1 7.8 8.3 5.1 7.1 5.8 1.5 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) NACHT PF05729.7 ETO06542.1 - 9.2e-08 31.9 0.0 1.6e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain DUF4014 PF13198.1 ETO06542.1 - 0.17 12.2 1.7 0.59 10.5 0.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4014) SSP160 PF06933.6 ETO06544.1 - 0.004 15.2 5.5 0.0057 14.7 3.8 1.2 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 DUF1510 PF07423.6 ETO06544.1 - 3.4 6.9 17.4 0.28 10.5 2.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Pkinase PF00069.20 ETO06545.1 - 1.1e-45 155.8 0.0 1.6e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO06545.1 - 9.9e-21 73.9 0.1 6.8e-20 71.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase DUF1049 PF06305.6 ETO06545.1 - 0.079 12.4 0.0 0.22 11.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Kdo PF06293.9 ETO06545.1 - 0.083 11.9 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO06545.1 - 0.19 11.4 0.1 0.38 10.4 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family SLIDE PF09111.5 ETO06545.1 - 3.3 7.4 7.4 3.1 7.5 0.8 3.3 3 1 0 3 3 3 0 SLIDE Methyltransf_26 PF13659.1 ETO06547.1 - 3.7e-08 33.4 0.0 7.2e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETO06547.1 - 3.5e-05 23.2 0.0 7.4e-05 22.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 ETO06547.1 - 0.0017 17.9 0.0 0.0093 15.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETO06547.1 - 0.033 14.5 0.1 0.072 13.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_28 PF02636.12 ETO06547.1 - 0.053 12.9 0.0 0.076 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase ICMT PF04140.9 ETO06547.1 - 0.058 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Pkinase PF00069.20 ETO06549.1 - 0.00028 20.1 0.0 0.00046 19.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO06549.1 - 0.00032 19.8 0.0 0.00047 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase fn3 PF00041.16 ETO06550.1 - 0.0014 18.7 0.7 0.37 10.9 0.0 3.0 2 1 0 2 2 2 2 Fibronectin type III domain Pneumo_att_G PF05539.6 ETO06551.1 - 1.4 8.1 6.8 2.2 7.5 4.7 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G PSCyt2 PF07583.6 ETO06552.1 - 0.086 12.3 0.1 0.11 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1549) SprA-related PF12118.3 ETO06553.1 - 1.3 8.2 9.2 1.6 8.0 6.4 1.2 1 0 0 1 1 1 0 SprA-related family zf-C3HC4_2 PF13923.1 ETO06554.1 - 0.082 12.9 15.4 0.19 11.7 10.3 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF4501 PF14946.1 ETO06554.1 - 2.1 7.7 9.6 0.27 10.6 1.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4501) zf-C3HC4 PF00097.20 ETO06554.1 - 2.2 7.9 16.2 6.7 6.4 11.2 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Mucin PF01456.12 ETO06554.1 - 3 7.6 26.1 8.5 6.1 18.1 1.8 1 0 0 1 1 1 0 Mucin-like glycoprotein Apis_Csd PF11671.3 ETO06555.1 - 0.12 12.2 18.0 0.27 11.0 12.5 1.5 1 0 0 1 1 1 0 Complementary sex determiner protein WD40 PF00400.27 ETO06556.1 - 1.3e-20 72.3 12.0 1e-09 37.8 0.4 4.5 4 1 0 4 4 4 3 WD domain, G-beta repeat Marek_SORF3 PF07153.6 ETO06556.1 - 0.00095 17.9 1.0 0.2 10.3 0.1 2.1 1 1 1 2 2 2 2 Marek's disease-like virus SORF3 protein Nup160 PF11715.3 ETO06556.1 - 0.0042 15.2 0.2 0.94 7.5 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 HIN PF02760.10 ETO06556.1 - 0.015 14.7 0.6 3.8 6.8 0.0 2.2 2 0 0 2 2 2 0 HIN-200/IF120x domain TetM_leader PF08076.6 ETO06556.1 - 0.19 11.2 2.2 2 8.0 0.2 3.0 2 0 0 2 2 2 0 Tetracycline resistance determinant leader peptide B56 PF01603.15 ETO06557.1 - 3.1e-08 32.6 0.3 0.00045 18.9 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) Pex14_N PF04695.8 ETO06558.1 - 5.8 6.9 9.0 7.9 6.5 3.4 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CENP-F_leu_zip PF10473.4 ETO06559.1 - 0.0076 16.1 11.5 0.0076 16.1 8.0 5.1 5 1 1 6 6 6 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.6 ETO06559.1 - 0.094 12.6 0.1 0.094 12.6 0.1 6.1 7 0 0 7 7 7 0 Flagella accessory protein C (FlaC) KH_5 PF13184.1 ETO06559.1 - 0.16 11.7 0.2 0.16 11.7 0.1 3.4 3 1 0 3 3 3 0 NusA-like KH domain Reo_sigmaC PF04582.7 ETO06559.1 - 0.28 10.3 9.9 0.15 11.1 0.3 2.2 1 1 0 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 ETO06559.1 - 0.43 10.1 40.2 0.048 13.2 5.4 4.3 2 1 1 4 4 4 0 IncA protein EnY2 PF10163.4 ETO06560.1 - 0.024 14.5 3.9 0.024 14.5 2.7 1.7 2 0 0 2 2 2 0 Transcription factor e(y)2 Pkinase_Tyr PF07714.12 ETO06561.1 - 2.8e-40 138.0 0.0 4.9e-40 137.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 ETO06561.1 - 2.5e-26 92.3 0.0 6.4e-26 91.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase PF00069.20 ETO06562.1 - 2.3e-31 108.8 1.2 6.2e-31 107.4 0.8 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO06562.1 - 1e-10 41.1 0.3 2e-08 33.6 0.1 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase UNC-50 PF05216.8 ETO06562.1 - 0.0071 15.5 1.6 0.012 14.8 1.1 1.3 1 0 0 1 1 1 1 UNC-50 family DUF3908 PF13048.1 ETO06563.1 - 3.8 7.5 7.6 1.2 9.1 2.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3908) WD40 PF00400.27 ETO06564.1 - 3.7e-46 153.4 26.5 2.4e-12 46.2 0.0 7.1 7 1 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO06564.1 - 5.2e-10 38.0 4.8 0.033 12.3 0.1 4.8 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Pox_Ag35 PF03286.9 ETO06565.1 - 4.3 6.8 58.0 0.068 12.6 12.8 3.4 3 0 0 3 3 3 0 Pox virus Ag35 surface protein TPR_12 PF13424.1 ETO06566.1 - 4.4e-158 513.5 36.0 2e-21 75.7 0.2 7.2 2 2 8 10 10 10 10 Tetratricopeptide repeat TPR_11 PF13414.1 ETO06566.1 - 3e-61 202.9 26.8 1.2e-12 47.2 0.3 7.6 7 1 0 7 7 7 6 TPR repeat TPR_10 PF13374.1 ETO06566.1 - 3.2e-53 176.2 0.0 2.1e-07 30.6 0.0 11.0 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_1 PF00515.23 ETO06566.1 - 1.6e-49 163.5 56.1 3.2e-07 29.6 0.7 11.4 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 ETO06566.1 - 7.1e-48 156.7 43.3 2.2e-06 27.1 0.5 11.3 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_7 PF13176.1 ETO06566.1 - 2.6e-46 151.7 11.6 9.3e-06 25.0 0.1 9.8 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_8 PF13181.1 ETO06566.1 - 5.5e-40 132.1 64.1 1.3e-06 27.7 1.5 10.6 11 0 0 11 11 10 10 Tetratricopeptide repeat TPR_16 PF13432.1 ETO06566.1 - 6.1e-21 74.5 0.4 0.00078 20.0 0.0 7.1 3 3 3 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.1 ETO06566.1 - 1.1e-18 65.8 10.7 0.61 10.4 0.0 11.1 10 2 0 10 10 10 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO06566.1 - 7.6e-18 63.4 0.0 2 9.2 0.0 9.2 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.1 ETO06566.1 - 9.8e-14 50.7 10.7 0.52 10.8 0.0 9.7 10 0 0 10 10 9 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO06566.1 - 5e-13 49.0 23.3 0.00078 19.5 0.2 5.9 1 1 5 7 7 7 7 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO06566.1 - 9.2e-10 38.7 2.4 0.35 11.2 0.1 5.5 3 1 3 7 7 7 4 Tetratricopeptide repeat MIT PF04212.13 ETO06566.1 - 4.9e-08 32.7 28.5 0.99 9.3 0.2 8.4 8 1 1 9 9 9 3 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.4 ETO06566.1 - 1.5e-06 27.3 3.5 3.8 6.8 0.0 6.7 7 0 0 7 7 7 1 SHNi-TPR TPR_3 PF07720.7 ETO06566.1 - 1.1e-05 25.1 30.6 0.25 11.1 0.3 8.3 8 0 0 8 8 8 3 Tetratricopeptide repeat Mob_Pre PF01076.14 ETO06566.1 - 0.00041 20.0 17.0 0.16 11.6 0.5 5.7 3 1 3 6 6 6 3 Plasmid recombination enzyme DUF627 PF04781.7 ETO06566.1 - 0.00058 19.4 13.7 5.5 6.6 0.1 7.3 3 2 6 9 9 9 1 Protein of unknown function (DUF627) Musclin PF11037.3 ETO06566.1 - 0.028 14.0 0.0 25 4.4 0.0 4.1 3 1 1 4 4 4 0 Insulin-resistance promoting peptide in skeletal muscle DUF3568 PF12092.3 ETO06566.1 - 0.037 13.7 6.2 15 5.3 0.0 5.4 1 1 3 6 6 6 0 Protein of unknown function (DUF3568) Sel1 PF08238.7 ETO06566.1 - 0.038 14.6 15.4 19 6.0 0.1 6.6 7 0 0 7 7 6 0 Sel1 repeat PPR PF01535.15 ETO06566.1 - 0.075 13.0 22.8 8.8 6.5 0.2 8.3 10 0 0 10 10 9 0 PPR repeat DUF4058 PF13267.1 ETO06566.1 - 0.5 9.4 3.0 12 4.9 0.0 3.8 2 1 2 4 4 4 0 Protein of unknown function (DUF4058) Sec5 PF15469.1 ETO06566.1 - 9 5.9 18.9 4.3 7.0 0.9 4.9 3 3 0 3 3 3 0 Exocyst complex component Sec5 Peroxin-13_N PF04088.8 ETO06567.1 - 0.022 14.7 0.0 0.027 14.4 0.0 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Sialidase PF02973.11 ETO06567.1 - 0.023 13.6 0.1 0.047 12.6 0.0 1.6 2 0 0 2 2 2 0 Sialidase, N-terminal domain UPF0270 PF06794.7 ETO06567.1 - 0.055 13.2 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0270) Exo_endo_phos_2 PF14529.1 ETO06568.1 - 0.00081 18.9 3.2 0.0032 17.0 1.4 2.5 1 1 1 2 2 2 1 Endonuclease-reverse transcriptase WD40 PF00400.27 ETO06571.1 - 6.3e-57 187.5 17.0 3.4e-12 45.7 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO06571.1 - 3.1e-06 26.2 5.1 0.0021 16.9 0.6 3.9 1 1 2 3 3 3 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO06571.1 - 3.7e-06 25.4 0.7 0.046 12.0 0.0 3.3 2 1 1 3 3 3 2 Cytochrome D1 heme domain Kelch_6 PF13964.1 ETO06571.1 - 6.6e-05 22.9 7.3 0.11 12.6 0.5 5.1 4 1 1 5 5 5 2 Kelch motif Gmad1 PF10647.4 ETO06571.1 - 0.0001 21.7 0.0 0.00043 19.7 0.0 1.9 2 0 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain Kelch_1 PF01344.20 ETO06571.1 - 0.00066 19.1 0.8 0.00066 19.1 0.6 3.1 3 0 0 3 3 3 1 Kelch motif NodS PF05401.6 ETO06571.1 - 0.049 13.0 0.0 0.23 10.8 0.0 2.1 2 0 0 2 2 2 0 Nodulation protein S (NodS) Kelch_4 PF13418.1 ETO06571.1 - 0.12 12.1 5.6 0.35 10.6 0.1 3.9 4 0 0 4 4 4 0 Galactose oxidase, central domain PD40 PF07676.7 ETO06571.1 - 0.45 10.2 4.0 26 4.6 0.1 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Kelch_5 PF13854.1 ETO06571.1 - 0.56 10.2 3.1 0.72 9.8 0.7 2.4 2 0 0 2 2 2 0 Kelch motif Kelch_2 PF07646.10 ETO06571.1 - 2.6 7.9 6.9 5.5 6.9 0.7 4.2 4 1 0 4 4 4 0 Kelch motif DUF3321 PF11968.3 ETO06573.1 - 0.027 14.1 0.1 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase (DUF3321) CTNNB1_binding PF08347.6 ETO06574.1 - 0.28 11.4 7.7 0.55 10.4 5.3 1.4 1 1 0 1 1 1 0 N-terminal CTNNB1 binding DUF3944 PF13099.1 ETO06575.1 - 0.0011 18.3 2.6 7.7 6.1 0.0 4.5 4 0 0 4 4 4 2 Domain of unknown function (DUF3944) IPK PF03770.11 ETO06575.1 - 0.022 14.3 1.9 0.025 14.2 0.2 1.9 2 0 0 2 2 2 0 Inositol polyphosphate kinase INTS5_N PF14837.1 ETO06575.1 - 1.3 8.3 6.0 1 8.7 0.3 3.2 3 1 1 4 4 4 0 Integrator complex subunit 5 N-terminus SMC_N PF02463.14 ETO06575.1 - 2 7.5 4.6 0.42 9.7 0.4 1.9 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain FH2 PF02181.18 ETO06576.1 - 1.8e-12 46.8 0.2 2.1e-12 46.6 0.1 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain FH2 PF02181.18 ETO06577.1 - 2.8e-40 138.3 13.7 3.4e-28 98.6 1.6 3.2 2 1 0 2 2 2 2 Formin Homology 2 Domain DUF2208 PF09973.4 ETO06577.1 - 0.0079 15.4 3.2 0.016 14.4 2.2 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2208) DUF2232 PF09991.4 ETO06577.1 - 0.042 12.8 0.4 0.11 11.4 0.3 1.7 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) GFO_IDH_MocA PF01408.17 ETO06578.1 - 1.3e-09 38.5 0.0 2e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Put_DNA-bind_N PF06971.8 ETO06578.1 - 0.1 12.3 0.2 1.7 8.4 0.0 2.6 2 1 0 2 2 2 0 Putative DNA-binding protein N-terminus BLVR PF06375.6 ETO06578.1 - 0.62 9.8 4.9 0.12 12.2 0.9 1.7 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) RCC1 PF00415.13 ETO06579.1 - 1.1e-21 76.7 14.0 9.4e-09 35.3 0.0 5.2 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO06579.1 - 2.6e-19 68.3 22.1 5.3e-09 35.4 4.6 3.8 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat TSP_1 PF00090.14 ETO06580.1 - 0.052 13.6 8.2 0.14 12.2 5.7 1.9 1 1 0 1 1 1 0 Thrombospondin type 1 domain AIP3 PF03915.8 ETO06581.1 - 0.0072 15.2 19.8 0.008 15.1 13.7 1.0 1 0 0 1 1 1 1 Actin interacting protein 3 TMF_DNA_bd PF12329.3 ETO06581.1 - 0.015 15.0 27.7 0.023 14.4 7.7 2.5 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.6 ETO06581.1 - 0.015 13.9 26.3 0.017 13.8 18.3 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Myosin_tail_1 PF01576.14 ETO06581.1 - 0.023 12.4 24.4 0.026 12.2 16.9 1.0 1 0 0 1 1 1 0 Myosin tail DUF641 PF04859.7 ETO06581.1 - 0.045 13.5 18.4 0.31 10.7 5.7 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) APG6 PF04111.7 ETO06581.1 - 0.1 11.5 21.4 0.13 11.3 14.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Prefoldin PF02996.12 ETO06581.1 - 0.17 11.5 24.8 2.1 8.0 2.8 3.1 3 0 0 3 3 3 0 Prefoldin subunit Tropomyosin_1 PF12718.2 ETO06581.1 - 0.17 11.7 26.9 0.1 12.4 4.5 2.1 1 1 1 2 2 2 0 Tropomyosin like HiaBD2 PF15403.1 ETO06581.1 - 0.17 12.0 0.4 0.17 12.0 0.3 2.6 2 1 1 3 3 2 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) ATG16 PF08614.6 ETO06581.1 - 0.22 11.3 25.7 0.87 9.3 9.0 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.1 ETO06581.1 - 0.39 9.1 23.1 0.56 8.5 16.0 1.2 1 0 0 1 1 1 0 AAA domain TBPIP PF07106.8 ETO06581.1 - 0.59 9.6 27.1 2.3 7.7 14.6 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HlyD PF00529.15 ETO06581.1 - 0.76 9.0 12.4 0.94 8.7 8.6 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Reo_sigmaC PF04582.7 ETO06581.1 - 0.98 8.5 4.5 1.5 7.8 3.1 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 ETO06581.1 - 0.99 9.2 17.9 2.1 8.1 3.5 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.14 ETO06581.1 - 1.1 7.0 17.0 1.2 6.9 11.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phage_GP20 PF06810.6 ETO06581.1 - 1.2 8.5 28.7 6.8 6.1 9.6 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 TPR_MLP1_2 PF07926.7 ETO06581.1 - 1.3 8.8 26.2 2.8 7.6 13.5 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Ald_Xan_dh_C2 PF02738.13 ETO06581.1 - 1.3 7.2 3.7 1.5 7.0 2.6 1.1 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase DUF342 PF03961.8 ETO06581.1 - 1.7 6.9 18.4 2.5 6.4 12.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Fib_alpha PF08702.5 ETO06581.1 - 1.8 8.6 25.5 6.4 6.8 5.3 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Atg14 PF10186.4 ETO06581.1 - 1.8 7.3 23.8 3.2 6.5 16.5 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4200 PF13863.1 ETO06581.1 - 2 8.3 32.1 39 4.1 22.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Neugrin PF06413.6 ETO06581.1 - 2.7 7.7 11.8 1.1 9.0 6.2 1.7 1 1 1 2 2 2 0 Neugrin DUF4613 PF15390.1 ETO06581.1 - 2.7 6.0 19.2 3 5.8 13.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF272 PF03312.10 ETO06581.1 - 2.8 8.1 9.8 0.75 10.0 4.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF272) Uds1 PF15456.1 ETO06581.1 - 3.3 7.7 15.9 8.1 6.4 9.5 2.0 1 1 1 2 2 2 0 Up-regulated During Septation Muted PF14942.1 ETO06581.1 - 3.4 7.5 20.7 2.2 8.1 12.2 1.9 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein IZUMO PF15005.1 ETO06581.1 - 3.6 7.6 12.3 5 7.1 8.5 1.1 1 0 0 1 1 1 0 Izumo sperm-egg fusion DUF948 PF06103.6 ETO06581.1 - 3.6 7.4 15.7 1.1 9.1 3.4 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) SlyX PF04102.7 ETO06581.1 - 4 7.8 22.7 14 6.1 10.4 2.6 1 1 1 2 2 2 0 SlyX DUF4407 PF14362.1 ETO06581.1 - 5.4 5.8 11.3 7.1 5.4 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IncA PF04156.9 ETO06581.1 - 6.7 6.2 26.0 16 5.0 18.0 1.6 1 1 0 1 1 1 0 IncA protein DUF2265 PF10023.4 ETO06581.1 - 7.1 5.6 11.7 7.8 5.5 8.1 1.1 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) GrpE PF01025.14 ETO06581.1 - 7.7 6.0 20.6 2 7.9 5.2 2.1 1 1 1 2 2 2 0 GrpE DUF2968 PF11180.3 ETO06581.1 - 8.3 5.7 22.8 3.1 7.1 12.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) TMPIT PF07851.8 ETO06581.1 - 8.6 5.3 20.8 0.35 9.8 8.9 1.9 1 1 1 2 2 2 0 TMPIT-like protein Astro_capsid PF03115.9 ETO06582.1 - 0.39 8.9 8.0 0.51 8.5 5.5 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor IncA PF04156.9 ETO06582.1 - 5.4 6.5 11.1 8.5 5.9 7.7 1.2 1 0 0 1 1 1 0 IncA protein WRKY PF03106.10 ETO06583.1 - 0.043 13.6 4.1 0.74 9.6 0.0 2.5 2 0 0 2 2 2 0 WRKY DNA -binding domain YscJ_FliF_C PF08345.6 ETO06584.1 - 0.013 15.4 0.5 0.013 15.4 0.3 1.4 2 0 0 2 2 2 0 Flagellar M-ring protein C-terminal DUF3796 PF12676.2 ETO06584.1 - 1.3 9.3 10.5 17 5.6 4.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3796) RBFA PF02033.13 ETO06584.1 - 3.3 7.7 7.4 0.97 9.4 0.3 3.1 3 2 0 3 3 3 0 Ribosome-binding factor A Peptidase_C14 PF00656.17 ETO06585.1 - 0.00014 21.6 0.1 0.0018 18.0 0.1 2.4 1 1 0 1 1 1 1 Caspase domain WD40 PF00400.27 ETO06586.1 - 7.9e-07 28.7 0.5 0.016 15.0 0.1 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat WD40 PF00400.27 ETO06587.1 - 0.0013 18.4 0.6 3.2 7.7 0.0 4.7 3 1 1 4 4 4 2 WD domain, G-beta repeat Ca_hom_mod PF14798.1 ETO06588.1 - 0.017 14.0 2.6 0.021 13.8 1.8 1.2 1 0 0 1 1 1 0 Calcium homeostasis modulator Cleaved_Adhesin PF07675.6 ETO06589.1 - 0.036 13.6 0.5 0.088 12.3 0.1 1.7 2 0 0 2 2 2 0 Cleaved Adhesin Domain DUF1510 PF07423.6 ETO06590.1 - 0.24 10.7 45.9 0.27 10.5 31.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) MIP-T3 PF10243.4 ETO06590.1 - 0.64 8.4 51.4 0.69 8.3 35.6 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2201_N PF13203.1 ETO06590.1 - 2.1 7.4 20.9 2.2 7.3 14.5 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain Ycf1 PF05758.7 ETO06590.1 - 4.3 4.9 31.9 4.2 4.9 22.1 1.0 1 0 0 1 1 1 0 Ycf1 Borrelia_P83 PF05262.6 ETO06590.1 - 7.5 4.7 41.7 9 4.4 28.9 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Neur_chan_memb PF02932.11 ETO06590.1 - 7.5 6.3 14.4 8.4 6.2 10.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SPOUT_MTase PF02590.12 ETO06591.1 - 1.7 8.3 4.8 0.74 9.5 0.4 2.1 2 0 0 2 2 2 0 Predicted SPOUT methyltransferase KfrA_N PF11740.3 ETO06593.1 - 1.4 9.3 3.9 58 4.1 0.2 3.2 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term MinC_N PF05209.8 ETO06594.1 - 0.0059 16.3 0.0 0.02 14.6 0.0 1.9 1 0 0 1 1 1 1 Septum formation inhibitor MinC, N-terminal domain RE_Bsp6I PF09504.5 ETO06595.1 - 0.044 13.2 0.1 0.086 12.2 0.0 1.5 1 0 0 1 1 1 0 Bsp6I restriction endonuclease AAA PF00004.24 ETO06596.1 - 3.9e-12 46.4 0.0 9.8e-07 29.0 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETO06596.1 - 3.9e-08 33.1 0.5 0.00025 20.7 0.0 4.1 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETO06596.1 - 1.1e-06 28.8 0.1 0.0078 16.3 0.1 3.4 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 ETO06596.1 - 1.7e-06 27.9 0.1 0.014 15.2 0.0 3.2 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 ETO06596.1 - 2e-05 24.8 0.2 0.00037 20.8 0.0 2.8 3 0 0 3 3 2 1 ABC transporter AAA_16 PF13191.1 ETO06596.1 - 6.9e-05 22.9 0.2 0.0065 16.4 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain DUF258 PF03193.11 ETO06596.1 - 0.00034 19.8 0.0 0.00084 18.5 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Viral_helicase1 PF01443.13 ETO06596.1 - 0.00074 19.0 0.2 0.11 11.9 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_2 PF07724.9 ETO06596.1 - 0.00076 19.4 0.0 0.024 14.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Arch_ATPase PF01637.13 ETO06596.1 - 0.0029 17.3 0.6 0.057 13.0 0.0 2.9 3 0 0 3 3 3 1 Archaeal ATPase PduV-EutP PF10662.4 ETO06596.1 - 0.0035 16.8 0.1 0.018 14.5 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 ETO06596.1 - 0.0061 15.5 0.4 0.02 13.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Miro PF08477.8 ETO06596.1 - 0.014 15.9 0.4 0.13 12.7 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein Sigma54_activ_2 PF14532.1 ETO06596.1 - 0.014 15.4 0.0 0.16 11.9 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 ETO06596.1 - 0.015 14.7 0.3 0.56 9.6 0.0 3.1 4 0 0 4 4 2 0 Sigma-54 interaction domain NACHT PF05729.7 ETO06596.1 - 0.015 14.9 0.1 0.38 10.4 0.0 2.7 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.12 ETO06596.1 - 0.017 14.5 0.0 1.7 8.0 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 ETO06596.1 - 0.034 13.3 0.4 4.1 6.4 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 ETO06596.1 - 0.048 13.8 0.1 1.7 8.8 0.0 3.0 2 0 0 2 2 2 0 RNA helicase Aldo_ket_red PF00248.16 ETO06596.1 - 0.06 12.1 0.0 0.13 11.0 0.0 1.5 1 1 0 1 1 1 0 Aldo/keto reductase family DUF677 PF05055.7 ETO06597.1 - 0.0037 15.9 1.7 0.0052 15.4 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF677) DUF1510 PF07423.6 ETO06597.1 - 0.017 14.5 0.7 0.026 13.8 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Shisa PF13908.1 ETO06597.1 - 0.18 11.9 0.7 0.2 11.8 0.1 1.5 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Tweety PF04906.8 ETO06597.1 - 0.4 9.0 4.2 0.094 11.1 0.6 1.5 2 0 0 2 2 2 0 Tweety SP_C-Propep PF08999.5 ETO06597.1 - 1.3 8.5 9.9 0.22 11.0 3.6 1.9 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide Ribosomal_60s PF00428.14 ETO06597.1 - 2.7 8.4 18.2 5.8 7.3 7.7 2.4 1 1 1 2 2 2 0 60s Acidic ribosomal protein TMCO5 PF14992.1 ETO06598.1 - 0.029 13.4 7.1 0.047 12.8 4.9 1.3 1 0 0 1 1 1 0 TMCO5 family Spot_14 PF07084.7 ETO06599.1 - 0.017 14.9 0.3 0.017 14.9 0.2 1.6 2 0 0 2 2 2 0 Thyroid hormone-inducible hepatic protein Spot 14 Nucleoporin_N PF08801.6 ETO06599.1 - 0.021 13.5 0.0 0.026 13.2 0.0 1.1 1 0 0 1 1 1 0 Nup133 N terminal like WD40 PF00400.27 ETO06600.1 - 1.7e-33 113.2 13.0 4.8e-07 29.4 0.0 6.1 7 0 0 7 7 7 5 WD domain, G-beta repeat DUF607 PF04678.8 ETO06601.1 - 2.3 8.1 5.4 8.9 6.1 3.8 2.1 1 1 0 1 1 1 0 Protein of unknown function, DUF607 zf-HC5HC2H_2 PF13832.1 ETO06602.1 - 0.12 12.4 1.0 0.23 11.4 0.7 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain Herpes_UL25 PF01499.11 ETO06603.1 - 0.057 11.7 4.4 0.087 11.1 3.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF1216 PF06746.6 ETO06603.1 - 0.15 11.8 3.2 0.27 11.0 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1216) AAA_23 PF13476.1 ETO06603.1 - 0.98 9.7 5.4 1.6 9.0 3.8 1.3 1 0 0 1 1 1 0 AAA domain DUF1843 PF08898.5 ETO06603.1 - 1 9.4 3.2 4.6 7.3 0.6 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) SlyX PF04102.7 ETO06603.1 - 6.6 7.1 9.5 0.37 11.1 0.7 3.2 4 0 0 4 4 4 0 SlyX XK-related PF09815.4 ETO06604.1 - 2.3e-08 33.4 4.6 2.3e-08 33.4 3.2 3.4 2 2 1 3 3 3 1 XK-related protein DUF2071 PF09844.4 ETO06604.1 - 0.026 13.9 0.5 0.042 13.2 0.3 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (COG2071) DPM2 PF07297.7 ETO06605.1 - 3.8 7.8 8.5 0.24 11.6 2.2 1.7 2 0 0 2 2 2 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Asn_synthase PF00733.16 ETO06606.1 - 2.5e-16 59.9 0.0 3.3e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase WD40 PF00400.27 ETO06607.1 - 8e-13 47.7 0.1 2e-05 24.3 0.0 3.3 3 1 0 3 3 3 2 WD domain, G-beta repeat Guanylate_cyc PF00211.15 ETO06608.1 - 3.1e-24 85.3 0.0 3.9e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF2453 PF10507.4 ETO06608.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2453) Pox_polyA_pol PF03296.8 ETO06609.1 - 0.014 14.9 0.3 0.029 13.9 0.0 1.6 2 0 0 2 2 2 0 Poxvirus poly(A) polymerase nucleotidyltransferase domain Med30 PF11315.3 ETO06609.1 - 0.21 11.6 0.2 0.21 11.6 0.1 2.6 2 1 1 3 3 3 0 Mediator complex subunit 30 DUF1954 PF09199.5 ETO06609.1 - 0.23 11.6 3.1 16 5.7 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1954) Ndc80_HEC PF03801.8 ETO06610.1 - 0.029 13.7 2.1 0.046 13.1 1.5 1.3 1 0 0 1 1 1 0 HEC/Ndc80p family RNA_binding PF01877.12 ETO06610.1 - 0.05 13.6 1.5 0.064 13.2 1.0 1.3 1 0 0 1 1 1 0 RNA binding Cnd1 PF12717.2 ETO06610.1 - 0.19 11.5 6.3 0.21 11.4 4.3 1.1 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 P16-Arc PF04699.9 ETO06610.1 - 0.24 11.4 1.4 0.42 10.6 0.7 1.5 1 1 1 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) Uteroglobin PF01099.12 ETO06610.1 - 0.3 10.9 2.7 2.3 8.1 0.1 2.4 2 0 0 2 2 2 0 Uteroglobin family NACHT PF05729.7 ETO06611.1 - 2.7e-07 30.4 0.0 3.7e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 ETO06611.1 - 0.00027 19.9 0.1 0.00048 19.0 0.0 1.5 1 1 1 2 2 2 1 NB-ARC domain DUF2075 PF09848.4 ETO06611.1 - 0.00048 19.2 0.1 0.0011 17.9 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 ETO06611.1 - 0.0035 17.0 0.0 0.0053 16.4 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 ETO06611.1 - 0.0055 16.1 0.0 0.0088 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 ETO06611.1 - 0.0063 16.6 0.3 0.3 11.2 0.0 2.4 2 1 0 2 2 2 1 RNA helicase AAA_22 PF13401.1 ETO06611.1 - 0.011 15.9 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 ETO06611.1 - 0.013 15.7 1.0 0.085 13.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 ETO06611.1 - 0.015 14.7 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.1 ETO06611.1 - 0.025 14.1 0.4 0.13 11.7 0.0 1.9 1 1 1 2 2 2 0 AAA domain Herpes_Helicase PF02689.9 ETO06611.1 - 0.028 12.1 0.0 0.035 11.8 0.0 1.1 1 0 0 1 1 1 0 Helicase BSP_II PF05432.6 ETO06611.1 - 0.035 13.3 3.9 0.048 12.9 2.7 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) KaiC PF06745.8 ETO06611.1 - 0.064 12.3 0.0 0.11 11.6 0.0 1.3 1 1 0 1 1 1 0 KaiC PhoH PF02562.11 ETO06611.1 - 0.069 12.3 0.0 0.087 12.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.10 ETO06611.1 - 0.076 12.8 1.3 0.12 12.2 0.9 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.1 ETO06611.1 - 0.091 12.7 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Vfa1 PF08432.5 ETO06611.1 - 1.5 8.8 7.2 1.9 8.4 5.0 1.2 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 WD40 PF00400.27 ETO06612.1 - 1e-23 82.2 8.7 2.7e-08 33.3 0.4 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF851 PF05867.6 ETO06612.1 - 0.035 13.3 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF851) DUF2344 PF10105.4 ETO06613.1 - 0.5 9.8 8.3 1.5 8.2 6.1 1.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) hDGE_amylase PF14701.1 ETO06613.1 - 7.2 5.3 13.5 9.2 5.0 9.3 1.1 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme G-alpha PF00503.15 ETO06615.1 - 1.2e-110 369.8 13.6 2e-110 369.1 9.4 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO06615.1 - 4.6e-10 38.9 2.4 1.9e-06 27.2 0.2 3.2 2 1 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 ETO06615.1 - 0.005 16.3 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 ETO06615.1 - 0.014 15.3 0.2 5.8 6.8 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase Miro PF08477.8 ETO06615.1 - 0.032 14.7 6.1 2.5 8.6 0.1 3.3 4 1 0 4 4 4 0 Miro-like protein FtsK_SpoIIIE PF01580.13 ETO06615.1 - 0.037 13.5 0.6 0.2 11.0 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_tran PF00005.22 ETO06615.1 - 1.2 9.4 5.4 0.64 10.3 0.4 2.7 2 1 1 3 3 3 0 ABC transporter DivIC PF04977.10 ETO06615.1 - 3.9 7.0 15.3 2.4 7.7 0.8 2.6 2 0 0 2 2 2 0 Septum formation initiator Ion_trans_2 PF07885.11 ETO06617.1 - 6.4e-08 32.1 7.8 6.4e-08 32.1 5.4 2.8 2 1 0 2 2 2 1 Ion channel Ion_trans_N PF08412.5 ETO06617.1 - 0.00018 20.7 0.9 0.00018 20.7 0.7 2.0 2 1 0 2 2 2 1 Ion transport protein N-terminal cNMP_binding PF00027.24 ETO06617.1 - 0.11 12.2 0.1 1 9.2 0.0 2.2 1 1 0 1 1 1 0 Cyclic nucleotide-binding domain Acyltransferase PF01553.16 ETO06618.1 - 0.0019 17.6 0.2 0.0061 16.0 0.1 1.8 1 0 0 1 1 1 1 Acyltransferase EF-hand_1 PF00036.27 ETO06618.1 - 0.0052 16.0 4.2 0.18 11.1 0.8 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 ETO06618.1 - 0.02 14.7 3.4 0.48 10.4 1.1 2.9 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.1 ETO06618.1 - 0.044 13.9 1.0 0.7 10.0 0.3 2.5 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.1 ETO06618.1 - 0.044 13.1 3.1 0.1 12.0 0.5 2.4 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.1 ETO06618.1 - 0.33 10.5 2.7 10 5.8 0.3 2.6 2 0 0 2 2 2 0 EF-hand domain pair WD40 PF00400.27 ETO06619.1 - 8.6e-63 206.1 32.9 4.1e-11 42.3 0.6 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO06619.1 - 3.1e-08 32.2 3.6 0.0027 15.9 0.1 4.5 2 2 1 4 4 4 4 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO06619.1 - 8.3e-05 22.8 2.0 0.00042 20.6 1.4 2.3 1 0 0 1 1 1 1 TRAF-type zinc finger Med9 PF07544.8 ETO06619.1 - 0.33 10.7 12.6 0.095 12.4 4.3 2.6 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 TPR_MLP1_2 PF07926.7 ETO06619.1 - 0.46 10.2 24.8 0.41 10.3 12.0 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein FadA PF09403.5 ETO06619.1 - 2.4 8.2 21.8 0.53 10.3 12.0 2.2 1 1 1 2 2 2 0 Adhesion protein FadA DUF2340 PF10209.4 ETO06619.1 - 3.3 7.8 13.9 0.17 12.0 3.8 3.0 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2340) HIRAN PF08797.6 ETO06620.1 - 0.0048 16.7 0.0 0.064 13.1 0.0 2.2 2 0 0 2 2 2 1 HIRAN domain Filament PF00038.16 ETO06621.1 - 0.00051 19.6 22.8 0.00051 19.6 15.8 2.4 1 1 2 3 3 3 1 Intermediate filament protein PilJ PF13675.1 ETO06621.1 - 0.088 13.1 10.0 2.1 8.7 4.5 2.5 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term zf-C3HC4_2 PF13923.1 ETO06621.1 - 0.12 12.4 4.2 0.75 9.8 2.9 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Phage_GP20 PF06810.6 ETO06621.1 - 1.2 8.5 52.0 0.19 11.1 18.7 3.3 1 1 2 3 3 3 0 Phage minor structural protein GP20 AAA_33 PF13671.1 ETO06622.1 - 5e-12 45.8 0.0 7.7e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO06622.1 - 2.3e-07 31.6 0.2 4.2e-07 30.8 0.1 1.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 ETO06622.1 - 1.7e-05 24.1 0.4 2.7e-05 23.5 0.3 1.3 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.1 ETO06622.1 - 2.3e-05 24.7 0.3 6.2e-05 23.3 0.0 1.9 1 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETO06622.1 - 0.00049 20.2 0.0 0.00081 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 ETO06622.1 - 0.001 18.5 0.2 0.0029 17.0 0.1 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 ETO06622.1 - 0.0019 17.8 0.0 0.003 17.2 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain 6PF2K PF01591.13 ETO06622.1 - 0.0024 16.9 0.2 0.0058 15.7 0.0 1.7 2 0 0 2 2 2 1 6-phosphofructo-2-kinase Zeta_toxin PF06414.7 ETO06622.1 - 0.0027 16.8 0.1 0.066 12.3 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin AAA_14 PF13173.1 ETO06622.1 - 0.0037 17.1 0.1 0.0075 16.1 0.0 1.6 2 1 0 2 2 1 1 AAA domain NACHT PF05729.7 ETO06622.1 - 0.0048 16.5 0.0 0.012 15.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA PF00004.24 ETO06622.1 - 0.006 16.7 0.0 0.011 15.9 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 ETO06622.1 - 0.013 15.8 0.0 0.026 14.8 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 ETO06622.1 - 0.016 15.2 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.18 ETO06622.1 - 0.025 14.5 0.0 0.042 13.8 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 ETO06622.1 - 0.026 14.6 0.0 0.049 13.8 0.0 1.7 1 1 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.13 ETO06622.1 - 0.033 13.6 0.1 0.071 12.6 0.0 1.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.1 ETO06622.1 - 0.034 14.1 0.1 0.056 13.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 ETO06622.1 - 0.04 12.7 0.0 0.085 11.6 0.0 1.4 1 1 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.4 ETO06622.1 - 0.041 12.8 0.0 0.074 12.0 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 ETO06622.1 - 0.043 13.2 0.0 0.05 13.0 0.0 1.3 1 1 0 1 1 1 0 AAA-like domain AAA_5 PF07728.9 ETO06622.1 - 0.053 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) APS_kinase PF01583.15 ETO06622.1 - 0.076 12.6 0.0 0.45 10.1 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase NTPase_1 PF03266.10 ETO06622.1 - 0.083 12.5 0.0 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 NTPase YqfQ PF14181.1 ETO06623.1 - 0.93 9.5 5.1 0.22 11.5 0.8 1.8 2 0 0 2 2 2 0 YqfQ-like protein Suf PF05843.9 ETO06624.1 - 0.0077 15.9 0.3 0.0077 15.9 0.2 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) PAT1 PF09770.4 ETO06624.1 - 0.02 13.1 11.0 0.025 12.8 7.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PP_M1 PF03012.9 ETO06624.1 - 0.026 13.8 0.7 0.035 13.4 0.5 1.1 1 0 0 1 1 1 0 Phosphoprotein Pkinase_Tyr PF07714.12 ETO06626.1 - 0.0022 17.1 0.0 0.0033 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_4 PF14555.1 ETO06627.1 - 4.3e-07 29.3 0.1 7.3e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain DUF1488 PF07369.6 ETO06627.1 - 0.054 13.3 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1488) ARD PF03079.9 ETO06627.1 - 1.1 9.2 3.5 15 5.5 2.4 2.1 1 1 0 1 1 1 0 ARD/ARD' family KCl_Cotrans_1 PF03522.10 ETO06628.1 - 0.8 9.2 0.1 0.8 9.2 0.1 3.0 3 0 0 3 3 3 0 K-Cl Co-transporter type 1 (KCC1) Trypan_PARP PF05887.6 ETO06628.1 - 4.9 6.9 8.2 5.8 6.7 5.7 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF1463 PF07316.6 ETO06629.1 - 0.077 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1463) ATP-cone PF03477.11 ETO06629.1 - 0.62 10.5 4.9 0.56 10.6 0.1 3.1 2 2 2 4 4 4 0 ATP cone domain SURF6 PF04935.7 ETO06629.1 - 5.2 6.3 6.5 9.8 5.4 0.2 2.3 2 0 0 2 2 2 0 Surfeit locus protein 6 DUF2963 PF11178.3 ETO06630.1 - 0.071 12.5 0.1 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2963) G-alpha PF00503.15 ETO06631.1 - 1e-26 93.5 0.5 1.2e-26 93.2 0.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit FtsK_SpoIIIE PF01580.13 ETO06631.1 - 0.00034 20.1 0.0 0.00052 19.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 ETO06631.1 - 0.017 15.1 0.1 0.025 14.5 0.1 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 ETO06631.1 - 0.019 14.4 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 ETO06631.1 - 0.031 14.2 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.1 ETO06631.1 - 0.039 13.0 0.1 0.042 12.9 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.5 ETO06631.1 - 0.041 13.0 0.1 0.065 12.4 0.1 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Arf PF00025.16 ETO06631.1 - 0.087 12.0 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family ABC_tran PF00005.22 ETO06631.1 - 0.11 12.7 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 ABC transporter PaO PF08417.7 ETO06636.1 - 0.04 13.8 0.9 12 5.9 0.0 3.2 3 0 0 3 3 3 0 Pheophorbide a oxygenase Fascin PF06268.8 ETO06637.1 - 0.058 13.4 0.1 0.094 12.8 0.1 1.6 1 1 0 1 1 1 0 Fascin domain CAP_GLY PF01302.20 ETO06639.1 - 0.0069 16.0 1.6 2.9 7.6 0.1 3.0 3 2 0 3 3 3 2 CAP-Gly domain CCDC74_C PF14917.1 ETO06640.1 - 0.042 13.9 0.0 0.054 13.5 0.0 1.1 1 0 0 1 1 1 0 Coiled coil protein 74, C terminal Helicase_C PF00271.26 ETO06641.1 - 1.5e-10 40.7 0.0 3e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF551 PF04448.7 ETO06641.1 - 0.1 13.3 0.3 0.39 11.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF551) TFIIB PF00382.14 ETO06642.1 - 0.14 11.9 0.1 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat Pyr_redox PF00070.22 ETO06644.1 - 3.3e-17 62.6 0.0 6e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETO06644.1 - 3.8e-09 36.7 0.0 3.1e-06 27.2 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETO06644.1 - 0.00046 20.3 0.0 0.003 17.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 ETO06644.1 - 0.034 14.3 0.0 0.045 14.0 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Cyt-b5 PF00173.23 ETO06645.1 - 4.3e-24 84.1 0.1 6.2e-24 83.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Phage_T7_Capsid PF05396.6 ETO06646.1 - 0.043 13.9 0.1 0.28 11.3 0.0 2.2 2 1 0 2 2 2 0 Phage T7 capsid assembly protein DUF1394 PF07159.7 ETO06647.1 - 0.00018 20.7 0.1 0.00032 19.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) BAF1_ABF1 PF04684.8 ETO06648.1 - 2.9 6.6 9.5 5.7 5.6 6.6 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4557 PF15101.1 ETO06648.1 - 3.7 7.3 8.9 6.3 6.5 6.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF948 PF06103.6 ETO06648.1 - 4.1 7.3 7.4 6.9 6.6 5.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF3981 PF13139.1 ETO06649.1 - 0.026 14.4 0.5 0.062 13.3 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3981) SPOB_ab PF14682.1 ETO06649.1 - 0.04 13.7 0.0 0.13 12.0 0.0 1.9 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal Myco_arth_vir_N PF09610.5 ETO06649.1 - 6.4 6.8 9.3 0.1 12.5 1.0 2.1 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) RRN3 PF05327.6 ETO06650.1 - 0.98 7.4 3.5 1.3 7.0 2.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.9 ETO06650.1 - 2.8 5.8 11.1 3.3 5.6 7.7 1.2 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.11 ETO06650.1 - 6.6 5.6 7.7 6.9 5.5 2.6 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit SecA_DEAD PF07517.9 ETO06651.1 - 1.6e-08 34.1 0.0 4.3e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 SecA DEAD-like domain VWA_2 PF13519.1 ETO06651.1 - 0.0082 16.2 0.0 1.7 8.7 0.0 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain HECT PF00632.20 ETO06653.1 - 3.9e-37 128.0 0.3 4.8e-37 127.7 0.2 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF1957 PF09210.6 ETO06653.1 - 0.085 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1957) Kelch_5 PF13854.1 ETO06658.1 - 1.4e-05 24.9 0.3 0.0018 18.1 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 ETO06658.1 - 7.6e-05 22.7 0.4 0.00098 19.1 0.0 2.9 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.20 ETO06658.1 - 0.006 16.1 0.0 0.017 14.6 0.0 1.8 1 0 0 1 1 1 1 Kelch motif Kelch_3 PF13415.1 ETO06658.1 - 0.0082 16.2 0.1 0.034 14.3 0.0 2.1 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO06658.1 - 0.025 14.3 0.2 0.33 10.7 0.0 2.4 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO06658.1 - 0.063 13.0 0.1 0.27 11.0 0.1 2.1 1 0 0 1 1 1 0 Kelch motif C2 PF00168.25 ETO06659.1 - 2.3e-20 72.2 0.7 1.2e-19 69.8 0.2 2.0 2 0 0 2 2 2 1 C2 domain Shisa PF13908.1 ETO06659.1 - 0.034 14.3 0.6 0.053 13.6 0.4 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Ras PF00071.17 ETO06661.1 - 2.5e-59 199.2 1.0 3.3e-59 198.8 0.7 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO06661.1 - 8.7e-17 61.7 0.1 4.7e-16 59.3 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO06661.1 - 1.5e-14 53.6 0.3 1.9e-14 53.2 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO06661.1 - 1.9e-05 24.1 0.1 2.4e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 ETO06661.1 - 0.0032 16.6 0.2 0.0043 16.2 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 ETO06661.1 - 0.021 14.0 0.1 0.026 13.7 0.1 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Fucose_iso_C PF02952.12 ETO06662.1 - 0.0032 16.9 0.0 0.0073 15.8 0.0 1.6 1 0 0 1 1 1 1 L-fucose isomerase, C-terminal domain DUF2116 PF09889.4 ETO06663.1 - 0.12 12.1 1.1 17 5.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DNA_pol_B PF00136.16 ETO06664.1 - 0.016 13.9 0.5 0.016 13.9 0.3 1.1 1 0 0 1 1 1 0 DNA polymerase family B DUF2894 PF11445.3 ETO06664.1 - 0.054 13.7 0.1 0.056 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) XPG_I PF00867.13 ETO06666.1 - 1.4e-10 41.0 0.1 3.2e-10 39.9 0.0 1.7 2 0 0 2 2 2 1 XPG I-region T2SM_b PF10741.4 ETO06666.1 - 0.027 14.0 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M subtype b Kelch_6 PF13964.1 ETO06667.1 - 1e-08 34.9 3.7 0.0011 19.0 0.2 4.7 4 1 1 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO06667.1 - 2.2e-07 30.2 4.6 2.6e-05 23.6 0.4 4.0 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO06667.1 - 2.2e-05 24.1 1.0 0.12 12.2 0.0 3.6 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO06667.1 - 0.0087 16.2 0.0 0.14 12.3 0.0 2.9 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO06667.1 - 0.012 15.5 0.1 2.6 8.0 0.1 3.9 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.10 ETO06667.1 - 0.14 11.9 5.0 2.6 7.9 0.1 4.4 5 1 0 5 5 5 0 Kelch motif MFS_1 PF07690.11 ETO06669.1 - 8.5e-05 21.4 2.6 0.00011 21.0 1.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF898 PF05987.8 ETO06669.1 - 0.017 14.0 1.2 0.035 12.9 0.9 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF962 PF06127.6 ETO06670.1 - 5.1e-23 80.7 0.7 1.9e-22 78.9 0.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF962) ECH PF00378.15 ETO06671.1 - 6e-17 61.5 0.0 1e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 ETO06671.1 - 3.6e-10 40.0 0.0 2.9e-09 37.0 0.0 2.1 1 1 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region WXG100 PF06013.7 ETO06673.1 - 5.8e-05 23.0 2.5 0.00016 21.6 1.7 1.8 1 1 0 1 1 1 1 Proteins of 100 residues with WXG HALZ PF02183.13 ETO06673.1 - 0.0066 16.1 0.4 0.026 14.2 0.3 2.1 1 0 0 1 1 1 1 Homeobox associated leucine zipper TMPIT PF07851.8 ETO06673.1 - 0.38 9.7 27.9 1.9 7.5 10.5 2.8 1 1 1 2 2 2 0 TMPIT-like protein Peptidase_C2 PF00648.16 ETO06674.1 - 0.00024 20.1 0.0 0.0005 19.1 0.0 1.4 1 1 0 1 1 1 1 Calpain family cysteine protease DJ-1_PfpI PF01965.19 ETO06677.1 - 1.7e-17 63.2 0.0 5e-17 61.7 0.0 1.7 2 0 0 2 2 2 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 ETO06677.1 - 1.2e-07 31.1 0.5 2.9e-07 29.8 0.4 1.7 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family Herpes_env PF01673.13 ETO06677.1 - 0.03 12.8 0.1 0.039 12.5 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Saccharop_dh PF03435.13 ETO06677.1 - 0.077 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF4530 PF15039.1 ETO06678.1 - 0.031 14.1 0.2 0.044 13.6 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4530) DUF848 PF05852.6 ETO06678.1 - 0.081 12.7 5.3 0.13 12.1 3.6 1.4 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Baculo_PEP_C PF04513.7 ETO06678.1 - 0.11 12.2 3.3 0.15 11.8 2.2 1.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2935 PF11155.3 ETO06678.1 - 0.33 11.0 4.0 0.42 10.6 2.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) ARD PF03079.9 ETO06678.1 - 0.53 10.2 3.6 0.72 9.7 2.5 1.2 1 0 0 1 1 1 0 ARD/ARD' family CobT PF06213.7 ETO06680.1 - 0.00067 18.8 14.0 0.00094 18.3 9.7 1.3 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Daxx PF03344.10 ETO06680.1 - 0.027 12.9 24.7 0.037 12.5 17.1 1.2 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 ETO06680.1 - 0.093 10.7 13.8 0.13 10.2 9.6 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 ETO06680.1 - 2.2 6.1 36.0 0.4 8.5 22.3 1.6 1 1 0 1 1 1 0 Nop14-like family PfkB PF00294.19 ETO06682.1 - 1.1e-34 119.9 0.0 2.6e-34 118.7 0.0 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 ETO06682.1 - 0.00037 19.7 0.0 0.00069 18.8 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DUF3791 PF12668.2 ETO06682.1 - 0.073 12.6 0.5 0.22 11.1 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) Cache_1 PF02743.13 ETO06682.1 - 0.12 11.9 0.1 0.55 9.8 0.0 2.1 2 0 0 2 2 2 0 Cache domain F-box PF00646.28 ETO06683.1 - 0.0092 15.6 0.0 0.024 14.2 0.0 1.7 1 0 0 1 1 1 1 F-box domain Mitochondr_Som1 PF11093.3 ETO06683.1 - 0.84 9.4 5.0 0.64 9.8 1.0 2.5 2 1 1 3 3 3 0 Mitochondrial export protein Som1 DUF2149 PF09919.4 ETO06685.1 - 0.95 9.6 0.0 0.95 9.6 0.0 2.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2149) DUF3839 PF12943.2 ETO06686.1 - 2.3e-05 23.6 1.7 3.7e-05 22.9 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3839) Geminin PF07412.7 ETO06686.1 - 0.012 15.2 3.8 0.018 14.7 2.6 1.3 1 0 0 1 1 1 0 Geminin Methyltransf_29 PF03141.11 ETO06686.1 - 0.035 12.4 1.7 0.04 12.2 1.2 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Flavi_capsid PF01003.14 ETO06687.1 - 0.39 10.2 2.5 3.2 7.3 0.1 2.0 2 0 0 2 2 2 0 Flavivirus capsid protein C HAND PF09110.6 ETO06688.1 - 0.13 12.7 0.1 0.15 12.4 0.0 1.1 1 0 0 1 1 1 0 HAND zf-RanBP PF00641.13 ETO06689.1 - 0.0002 20.4 0.5 0.00037 19.5 0.3 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others SAGA-Tad1 PF12767.2 ETO06689.1 - 0.012 15.2 0.7 0.019 14.6 0.5 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit zf-Sec23_Sec24 PF04810.10 ETO06689.1 - 0.02 14.4 0.4 0.02 14.4 0.3 1.6 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger PGA2 PF07543.7 ETO06689.1 - 2.6 7.8 9.2 13 5.5 0.0 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 MyTH4 PF00784.12 ETO06690.1 - 1e-06 28.6 0.7 2.6e-06 27.3 0.4 1.6 1 1 0 1 1 1 1 MyTH4 domain Rep_N PF08724.5 ETO06690.1 - 0.096 12.2 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Rep protein catalytic domain like Telomere_Sde2 PF13019.1 ETO06692.1 - 2.1e-12 47.0 0.9 3.2e-12 46.4 0.6 1.3 1 0 0 1 1 1 1 Telomere stability and silencing FAM60A PF15396.1 ETO06692.1 - 0.0017 18.1 0.4 0.0021 17.8 0.3 1.1 1 0 0 1 1 1 1 Protein Family FAM60A DUF2361 PF10153.4 ETO06692.1 - 0.013 15.7 3.1 0.019 15.1 2.1 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) Lipoprotein_19 PF13617.1 ETO06692.1 - 0.11 12.1 1.0 0.21 11.2 0.7 1.5 1 0 0 1 1 1 0 YnbE-like lipoprotein PBP1_TM PF14812.1 ETO06692.1 - 0.16 12.2 10.2 0.39 11.0 7.0 1.6 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cytochrom_NNT PF03264.9 ETO06692.1 - 1.1 8.6 5.9 2 7.8 4.1 1.4 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region Rop-like PF05082.8 ETO06693.1 - 0.062 12.7 0.1 0.41 10.1 0.0 2.3 2 0 0 2 2 2 0 Rop-like IFNGR1 PF07140.6 ETO06694.1 - 0.037 13.7 3.1 0.081 12.6 2.2 1.7 1 1 0 1 1 1 0 Interferon gamma receptor (IFNGR1) AcetylCoA_hyd_C PF13336.1 ETO06696.1 - 0.15 11.7 2.3 0.21 11.2 1.6 1.2 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain DUF2217 PF10265.4 ETO06696.1 - 2.9 6.5 9.7 3.8 6.1 6.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF566 PF04484.7 ETO06696.1 - 6.4 6.1 17.6 8.1 5.8 12.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) NDUF_B4 PF07225.7 ETO06698.1 - 0.027 14.2 0.8 0.063 13.0 0.2 1.7 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) WD40 PF00400.27 ETO06700.1 - 1.5e-60 199.0 26.0 4.3e-11 42.2 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO06700.1 - 1.4e-08 33.3 3.6 0.089 10.9 0.0 4.5 2 1 3 5 5 5 4 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO06700.1 - 0.00027 21.2 2.4 0.00027 21.2 1.6 2.7 2 0 0 2 2 2 1 TRAF-type zinc finger BBS2_Mid PF14783.1 ETO06700.1 - 0.11 12.3 9.4 19 5.0 0.1 5.3 3 1 1 5 5 5 0 Ciliary BBSome complex subunit 2, middle region Kelch_5 PF13854.1 ETO06701.1 - 0.00033 20.5 0.1 0.83 9.6 0.0 2.2 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.1 ETO06701.1 - 0.0095 16.0 0.1 0.16 12.1 0.0 2.2 2 0 0 2 2 2 1 Kelch motif EpoR_lig-bind PF09067.5 ETO06701.1 - 0.037 14.0 0.9 0.059 13.3 0.2 1.6 1 1 0 1 1 1 0 Erythropoietin receptor, ligand binding SAM_1 PF00536.25 ETO06702.1 - 0.0049 17.0 0.0 0.011 15.9 0.0 1.6 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) RCR PF12273.3 ETO06703.1 - 0.011 16.2 0.1 0.018 15.5 0.0 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Peptidase_A8 PF01252.13 ETO06703.1 - 0.012 15.2 5.7 1.2 8.7 0.1 2.7 2 1 1 3 3 3 0 Signal peptidase (SPase) II DUF443 PF04276.7 ETO06703.1 - 0.02 14.3 0.5 0.031 13.7 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF443) DUF3522 PF12036.3 ETO06703.1 - 0.062 13.0 3.3 0.098 12.4 2.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3522) Cons_hypoth698 PF03601.9 ETO06703.1 - 0.074 11.6 0.9 0.14 10.8 0.2 1.6 2 0 0 2 2 2 0 Conserved hypothetical protein 698 PRCH PF03967.8 ETO06703.1 - 0.083 12.4 0.1 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region CstA PF02554.9 ETO06703.1 - 0.12 10.9 1.9 0.15 10.6 1.3 1.1 1 0 0 1 1 1 0 Carbon starvation protein CstA DUF1201 PF06716.6 ETO06703.1 - 0.78 9.6 4.1 1.4 8.7 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1201) PUB PF09409.5 ETO06704.1 - 0.084 12.6 0.1 0.34 10.6 0.1 2.0 1 1 0 1 1 1 0 PUB domain Choline_sulf_C PF12411.3 ETO06705.1 - 0.0082 15.9 0.4 0.022 14.5 0.1 1.8 2 0 0 2 2 2 1 Choline sulfatase enzyme C terminal DUF1510 PF07423.6 ETO06706.1 - 8.8e-06 25.2 7.0 1e-05 25.0 4.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) DUF2201_N PF13203.1 ETO06706.1 - 0.00036 19.8 3.3 0.00041 19.6 2.3 1.1 1 0 0 1 1 1 1 Putative metallopeptidase domain DDHD PF02862.12 ETO06706.1 - 0.0069 16.2 5.8 0.0085 15.9 4.0 1.2 1 0 0 1 1 1 1 DDHD domain Neur_chan_memb PF02932.11 ETO06706.1 - 0.011 15.6 4.0 0.013 15.4 2.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.2 ETO06706.1 - 0.017 12.8 8.6 0.021 12.5 6.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF913 PF06025.7 ETO06706.1 - 0.037 12.7 6.7 0.049 12.3 4.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) UPF0560 PF10577.4 ETO06706.1 - 0.042 12.1 7.1 0.052 11.8 4.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 SPX PF03105.14 ETO06706.1 - 0.043 13.6 16.4 0.057 13.1 11.4 1.1 1 0 0 1 1 1 0 SPX domain DUF262 PF03235.9 ETO06706.1 - 0.087 12.7 9.6 0.11 12.4 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 Zip PF02535.17 ETO06706.1 - 0.13 11.2 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PBP_sp32 PF07222.7 ETO06706.1 - 0.14 11.3 13.3 0.22 10.6 9.3 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 SAPS PF04499.10 ETO06706.1 - 0.18 10.4 12.4 0.22 10.0 8.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Vfa1 PF08432.5 ETO06706.1 - 0.21 11.5 25.7 0.29 11.1 17.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 ETO06706.1 - 0.23 9.4 17.2 0.29 9.1 11.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4557 PF15101.1 ETO06706.1 - 0.46 10.2 7.8 0.7 9.6 5.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) MIP-T3 PF10243.4 ETO06706.1 - 2.1 6.6 38.3 2.8 6.2 26.6 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 U79_P34 PF03064.11 ETO06706.1 - 2.7 7.4 25.0 3.6 7.0 17.3 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Band_3_cyto PF07565.8 ETO06706.1 - 3.7 6.9 8.7 4.8 6.6 6.0 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain EOS1 PF12326.3 ETO06706.1 - 6.2 6.4 10.3 1.1e+02 2.3 7.2 2.3 1 1 0 1 1 1 0 N-glycosylation protein SOBP PF15279.1 ETO06706.1 - 6.8 6.9 10.6 8.8 6.6 7.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein NPR3 PF03666.8 ETO06706.1 - 7.8 4.9 19.9 11 4.4 13.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PPC PF04151.10 ETO06709.1 - 0.0064 17.4 0.3 0.0064 17.4 0.2 4.7 2 1 0 2 2 2 1 Bacterial pre-peptidase C-terminal domain ARID PF01388.16 ETO06711.1 - 4.1e-13 48.9 0.5 6.5e-13 48.3 0.4 1.3 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.24 ETO06711.1 - 1.2e-05 24.9 5.2 2.4e-05 23.9 3.6 1.6 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 ETO06711.1 - 0.0006 19.4 1.4 0.0006 19.4 1.0 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 C1_1 PF00130.17 ETO06711.1 - 0.0018 17.9 1.3 0.0018 17.9 0.9 3.0 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Pox_D5 PF03288.11 ETO06711.1 - 0.12 12.6 0.1 0.24 11.7 0.1 1.5 1 0 0 1 1 1 0 Poxvirus D5 protein-like TPR_11 PF13414.1 ETO06712.1 - 6.2e-07 28.9 0.8 0.00029 20.4 0.0 2.4 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 ETO06712.1 - 0.27 11.2 1.3 1.8 8.6 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Mem_trans PF03547.13 ETO06714.1 - 0.12 10.5 0.1 0.099 10.9 0.1 1.1 1 0 0 1 1 1 0 Membrane transport protein Macoilin PF09726.4 ETO06714.1 - 0.45 8.7 5.8 0.6 8.3 4.1 1.2 1 0 0 1 1 1 0 Transmembrane protein SR-25 PF10500.4 ETO06714.1 - 1.1 8.6 20.1 2 7.8 13.9 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ARL2_Bind_BART PF11527.3 ETO06718.1 - 0.078 12.7 0.1 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART Transport_MerF PF11431.3 ETO06721.1 - 0.73 9.5 0.0 0.73 9.5 0.0 2.9 3 0 0 3 3 3 0 Membrane transport protein MerF TMPIT PF07851.8 ETO06722.1 - 2.4e-39 135.3 17.7 2.7e-35 121.9 8.4 2.0 1 1 1 2 2 2 2 TMPIT-like protein DUF842 PF05811.8 ETO06722.1 - 0.0018 17.7 1.8 0.0031 16.9 1.2 1.4 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) DUF1759 PF03564.10 ETO06722.1 - 0.036 13.8 3.1 0.14 11.9 1.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) Spore_YhaL PF14147.1 ETO06722.1 - 0.048 13.1 0.0 0.17 11.3 0.0 2.0 1 0 0 1 1 1 0 Sporulation protein YhaL BBP1_C PF15272.1 ETO06722.1 - 0.052 13.0 7.1 0.095 12.2 4.9 1.4 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal DUF3135 PF11333.3 ETO06722.1 - 0.066 13.3 0.3 0.15 12.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) COG5 PF10392.4 ETO06722.1 - 0.12 12.3 2.7 0.23 11.3 0.5 2.1 1 1 1 2 2 2 0 Golgi transport complex subunit 5 UMPH-1 PF05822.7 ETO06722.1 - 0.15 11.3 4.0 0.3 10.3 2.7 1.4 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) Seryl_tRNA_N PF02403.17 ETO06722.1 - 0.17 11.9 7.5 0.39 10.7 4.5 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DASH_Duo1 PF08651.5 ETO06722.1 - 0.54 9.8 5.7 0.2 11.2 1.5 2.1 2 1 1 3 3 3 0 DASH complex subunit Duo1 DUF2704 PF10866.3 ETO06722.1 - 0.63 9.4 6.9 0.16 11.3 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2704) DUF342 PF03961.8 ETO06722.1 - 2.6 6.3 8.1 3.5 5.9 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2413 PF10310.4 ETO06724.1 - 0.02 13.7 7.7 0.023 13.5 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Pup PF05639.6 ETO06724.1 - 0.049 14.1 4.7 0.049 14.1 3.3 2.3 1 1 1 2 2 2 0 Pup-like protein DUF3085 PF11284.3 ETO06724.1 - 0.11 12.7 0.2 0.17 12.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3085) Ribosomal_60s PF00428.14 ETO06724.1 - 2.6 8.5 7.4 6.2 7.2 5.1 1.8 1 1 0 1 1 1 0 60s Acidic ribosomal protein DHHW PF14286.1 ETO06724.1 - 3.6 6.8 7.2 4.3 6.5 5.0 1.0 1 0 0 1 1 1 0 DHHW protein GET2 PF08690.5 ETO06724.1 - 3.6 6.7 8.7 0.81 8.8 3.4 1.8 1 1 1 2 2 2 0 GET complex subunit GET2 PGA2 PF07543.7 ETO06724.1 - 4.2 7.1 8.4 5.9 6.6 5.8 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF4611 PF15387.1 ETO06724.1 - 5.6 7.1 18.3 3.2 7.9 4.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) Annexin PF00191.15 ETO06725.1 - 2.2e-21 75.5 4.8 8.7e-06 25.5 0.1 4.3 4 0 0 4 4 4 4 Annexin AAA_2 PF07724.9 ETO06726.1 - 0.045 13.6 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF2890 PF11081.3 ETO06727.1 - 4.9 7.1 13.8 6.1 6.8 9.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF3439 PF11921.3 ETO06728.1 - 0.037 13.7 2.1 0.059 13.1 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF3231 PF11553.3 ETO06728.1 - 0.081 12.4 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3231) adh_short_C2 PF13561.1 ETO06729.1 - 3.6e-32 112.0 0.7 1.5e-31 110.0 0.5 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETO06729.1 - 2.5e-24 86.0 1.4 2.1e-23 83.0 1.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETO06729.1 - 2.8e-08 33.6 0.7 2e-07 30.8 0.4 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 ETO06729.1 - 2.2e-05 24.0 0.3 5.5e-05 22.7 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETO06729.1 - 0.00012 22.1 1.0 0.0049 16.8 0.5 2.3 2 0 0 2 2 2 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 ETO06729.1 - 0.00097 18.2 0.3 0.00097 18.2 0.2 1.6 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ETRAMP PF09716.5 ETO06729.1 - 0.0056 16.5 0.1 1.1 9.2 0.0 2.7 2 0 0 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) 2-Hacid_dh_C PF02826.14 ETO06729.1 - 0.0095 15.1 0.2 0.016 14.3 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 ETO06729.1 - 0.016 14.8 1.4 0.025 14.2 1.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 ETO06729.1 - 0.062 13.1 2.3 0.47 10.2 2.0 2.1 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ApbA PF02558.11 ETO06729.1 - 0.082 12.3 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Helicase_RecD PF05127.9 ETO06729.1 - 0.11 12.0 0.4 0.28 10.8 0.3 1.6 1 1 0 1 1 1 0 Helicase Polysacc_deac_2 PF04748.8 ETO06729.1 - 0.12 11.4 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase Shikimate_DH PF01488.15 ETO06729.1 - 0.13 12.3 0.6 0.23 11.5 0.4 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 ETO06729.1 - 5.2 6.2 7.8 0.26 10.5 1.5 1.6 2 0 0 2 2 2 0 NmrA-like family Mucin PF01456.12 ETO06731.1 - 0.021 14.5 10.8 0.037 13.8 7.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Tmemb_9 PF05434.6 ETO06731.1 - 0.086 12.5 0.8 0.12 12.1 0.2 1.5 2 0 0 2 2 2 0 TMEM9 CENP-B_dimeris PF09026.5 ETO06732.1 - 0.0021 18.2 1.6 0.0039 17.4 1.1 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Myc_N PF01056.13 ETO06732.1 - 0.026 13.6 4.3 0.029 13.5 3.0 1.3 1 0 0 1 1 1 0 Myc amino-terminal region BSP_II PF05432.6 ETO06732.1 - 0.15 11.3 8.6 0.25 10.5 6.0 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) MscS_TM PF12794.2 ETO06732.1 - 0.57 8.7 2.6 0.78 8.2 1.8 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Spt5_N PF11942.3 ETO06732.1 - 2.8 8.6 13.8 1.9 9.1 5.9 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal CDV3 PF15359.1 ETO06732.1 - 3.1 7.8 9.3 7.5 6.6 6.5 1.6 1 1 0 1 1 1 0 Carnitine deficiency-associated protein 3 Mito_fiss_reg PF05308.6 ETO06734.1 - 0.018 14.4 2.2 0.034 13.5 1.5 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator IIGP PF05049.8 ETO06734.1 - 0.03 13.1 0.1 0.048 12.4 0.1 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Trypsin PF00089.21 ETO06735.1 - 4.7e-13 49.2 0.8 7.6e-13 48.5 0.6 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 ETO06735.1 - 2.1e-12 47.0 0.4 4.3e-12 46.0 0.2 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 ETO06735.1 - 7.6e-07 28.9 0.0 1.9e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 PDZ domain CDC45 PF02724.9 ETO06736.1 - 0.013 13.6 7.5 0.015 13.3 5.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 ETO06736.1 - 3.6 5.9 21.2 5.3 5.3 14.7 1.2 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 ETO06736.1 - 7 5.6 23.9 0.2 10.6 10.2 2.0 2 0 0 2 2 2 0 BUD22 DUF2722 PF10846.3 ETO06736.1 - 7.3 5.5 14.7 0.38 9.7 6.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF4414 PF14377.1 ETO06737.1 - 0.01 15.7 0.1 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4414) Pkinase PF00069.20 ETO06737.1 - 0.011 14.9 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain DUF912 PF06024.7 ETO06738.1 - 0.00026 20.9 2.6 0.00026 20.9 1.8 4.8 3 1 0 3 3 3 1 Nucleopolyhedrovirus protein of unknown function (DUF912) 7tm_1 PF00001.16 ETO06738.1 - 0.043 12.9 0.0 0.043 12.9 0.0 1.9 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) Acp26Ab PF05777.7 ETO06738.1 - 0.088 13.2 0.3 0.088 13.2 0.2 2.2 2 0 0 2 2 2 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) NAD_binding_10 PF13460.1 ETO06739.1 - 3e-14 53.4 0.0 3.6e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETO06739.1 - 1.1e-13 51.1 0.0 1.4e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETO06739.1 - 6.9e-11 41.3 0.0 9.1e-11 40.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 ETO06739.1 - 2.3e-05 23.7 0.0 8.4e-05 21.9 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 ETO06739.1 - 0.0021 18.0 0.0 0.0029 17.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 ETO06739.1 - 0.021 13.7 0.1 0.042 12.7 0.0 1.8 1 1 0 1 1 1 0 Male sterility protein DUF4384 PF14326.1 ETO06739.1 - 0.056 13.2 0.0 0.086 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4384) DUF1041 PF06292.12 ETO06739.1 - 0.12 12.5 0.1 0.17 12.0 0.1 1.3 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1041) Ras PF00071.17 ETO06740.1 - 2e-20 72.8 0.5 2.7e-20 72.3 0.4 1.2 1 0 0 1 1 1 1 Ras family UDG PF03167.14 ETO06740.1 - 0.013 14.9 0.0 0.032 13.7 0.0 1.3 1 1 0 1 1 1 0 Uracil DNA glycosylase superfamily DUF2093 PF09866.4 ETO06740.1 - 0.1 11.8 0.0 0.23 10.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2093) ABC_tran PF00005.22 ETO06741.1 - 4.4e-26 91.8 1.9 5.9e-26 91.3 0.0 2.0 2 1 0 2 2 2 1 ABC transporter AAA_22 PF13401.1 ETO06741.1 - 3e-06 27.3 0.1 1.6e-05 25.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETO06741.1 - 1.7e-05 24.9 0.4 3.8e-05 23.7 0.3 1.8 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 ETO06741.1 - 2e-05 23.9 0.4 0.022 14.0 0.1 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETO06741.1 - 2.4e-05 24.4 0.1 0.032 14.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 ETO06741.1 - 0.00016 21.1 0.1 0.00034 20.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 ETO06741.1 - 0.00024 21.9 0.0 0.0013 19.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 ETO06741.1 - 0.00051 20.2 0.1 0.15 12.2 0.1 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 ETO06741.1 - 0.0018 17.7 0.1 0.045 13.1 0.0 2.4 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 ETO06741.1 - 0.0034 16.6 0.4 0.0092 15.1 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 ETO06741.1 - 0.0046 17.2 0.0 0.021 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain Katanin_con80 PF13925.1 ETO06741.1 - 0.0063 16.2 1.6 0.021 14.5 0.2 2.1 1 1 1 2 2 2 1 con80 domain of Katanin AAA_33 PF13671.1 ETO06741.1 - 0.0095 15.8 1.5 0.045 13.6 0.8 2.4 1 1 0 1 1 1 1 AAA domain Glyco_hydro_79n PF03662.9 ETO06741.1 - 0.01 14.4 0.0 0.014 14.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 79, N-terminal domain AAA_5 PF07728.9 ETO06741.1 - 0.011 15.4 0.5 0.28 10.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) ThiS PF02597.15 ETO06741.1 - 0.013 15.9 0.2 0.042 14.2 0.2 1.9 1 0 0 1 1 1 0 ThiS family KAP_NTPase PF07693.9 ETO06741.1 - 0.041 12.8 1.1 0.24 10.3 0.8 2.0 1 1 0 1 1 1 0 KAP family P-loop domain MoaE PF02391.12 ETO06741.1 - 0.051 13.3 0.0 0.095 12.5 0.0 1.4 1 0 0 1 1 1 0 MoaE protein DUF87 PF01935.12 ETO06741.1 - 0.051 13.3 3.1 0.48 10.2 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function DUF87 AAA_10 PF12846.2 ETO06741.1 - 0.056 12.8 0.4 0.19 11.0 0.1 1.9 1 1 0 2 2 2 0 AAA-like domain VirE_N PF08800.5 ETO06741.1 - 0.12 12.1 0.2 0.45 10.2 0.1 2.1 2 1 0 2 2 2 0 VirE N-terminal domain AAA_23 PF13476.1 ETO06741.1 - 0.77 10.0 7.3 3 8.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain Fib_alpha PF08702.5 ETO06741.1 - 1.2 9.2 6.2 8.2 6.5 0.1 2.5 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family zf-TRAF PF02176.13 ETO06742.1 - 0.00019 21.7 1.9 0.00019 21.7 1.3 2.6 2 1 0 2 2 2 1 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 ETO06742.1 - 0.0068 16.4 0.6 0.074 13.0 0.5 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1644 PF07800.7 ETO06742.1 - 0.087 12.6 6.3 0.56 10.0 1.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) zf-C3HC4 PF00097.20 ETO06742.1 - 0.3 10.7 3.1 4.1 7.1 0.0 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2_4 PF13894.1 ETO06742.1 - 1.2 9.6 8.4 29 5.2 1.1 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-RING_2 PF13639.1 ETO06742.1 - 1.3 8.9 7.6 0.13 12.1 0.4 2.8 2 1 1 3 3 3 0 Ring finger domain PHD PF00628.24 ETO06742.1 - 4.7 6.9 8.6 4.1 7.1 1.4 2.7 2 0 0 2 2 2 0 PHD-finger zf-C2H2_jaz PF12171.3 ETO06742.1 - 7.3 6.8 8.1 1.5 9.0 0.2 3.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding RasGEF PF00617.14 ETO06743.1 - 6.6e-05 22.7 0.0 0.00018 21.2 0.0 1.7 1 1 0 1 1 1 1 RasGEF domain WVELL PF14043.1 ETO06743.1 - 0.042 13.4 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 WVELL protein PIP5K PF01504.13 ETO06744.1 - 4.4e-32 111.1 0.1 5.9e-32 110.7 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase PIP5K PF01504.13 ETO06745.1 - 8.1e-30 103.7 0.8 2e-29 102.4 0.6 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase CFTR_R PF14396.1 ETO06746.1 - 0.1 11.9 0.3 0.16 11.2 0.2 1.3 1 0 0 1 1 1 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain ALIX_LYPXL_bnd PF13949.1 ETO06747.1 - 4.2e-40 137.5 7.6 4.8e-40 137.3 5.3 1.0 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF904 PF06005.7 ETO06747.1 - 1.2 9.5 6.7 0.27 11.5 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF904) HAUS6_N PF14661.1 ETO06747.1 - 1.9 7.7 6.3 2.1 7.6 0.5 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Spectrin PF00435.16 ETO06747.1 - 10 6.4 8.3 1.2 9.5 0.8 2.9 3 1 0 3 3 3 0 Spectrin repeat Macoilin PF09726.4 ETO06748.1 - 3.3 5.8 18.5 4 5.5 12.8 1.0 1 0 0 1 1 1 0 Transmembrane protein Ilar_coat PF01787.11 ETO06749.1 - 0.35 10.4 3.7 0.18 11.3 1.2 1.5 2 0 0 2 2 2 0 Ilarvirus coat protein TEX19 PF15553.1 ETO06749.1 - 1.4 8.7 4.2 2.8 7.7 2.9 1.4 1 0 0 1 1 1 0 Testis-expressed protein 19 DUF626 PF04776.7 ETO06750.1 - 0.027 14.8 0.4 0.097 13.0 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF626) Tweety PF04906.8 ETO06750.1 - 7.8 4.7 8.0 0.54 8.6 0.6 2.3 3 0 0 3 3 3 0 Tweety PX PF00787.19 ETO06751.1 - 0.034 13.9 0.1 0.046 13.5 0.1 1.4 1 0 0 1 1 1 0 PX domain HALZ PF02183.13 ETO06752.1 - 0.0015 18.1 0.1 0.0015 18.1 0.1 5.2 5 1 0 5 5 5 2 Homeobox associated leucine zipper Cep57_CLD_2 PF14197.1 ETO06752.1 - 0.004 17.0 7.0 0.004 17.0 4.9 5.8 4 2 2 6 6 6 2 Centrosome localisation domain of PPC89 Snapin_Pallidin PF14712.1 ETO06752.1 - 0.016 15.5 14.6 0.016 15.5 10.1 5.1 5 1 0 5 5 5 0 Snapin/Pallidin Shugoshin_N PF07558.6 ETO06752.1 - 6.5 6.5 19.5 0.034 13.8 2.5 3.8 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Chorion_2 PF03964.10 ETO06753.1 - 8.9 6.9 14.9 19 5.8 6.5 2.5 2 0 0 2 2 2 0 Chorion family 2 Abhydrolase_5 PF12695.2 ETO06754.1 - 1.1e-13 51.1 0.0 1.9e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETO06754.1 - 2e-09 37.6 0.0 2.3e-08 34.2 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETO06754.1 - 1.6e-07 30.7 0.0 0.00083 18.6 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 ETO06754.1 - 1.3e-05 24.9 0.3 0.01 15.3 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.8 ETO06754.1 - 0.00019 20.9 0.0 0.00031 20.2 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S15 PF02129.13 ETO06754.1 - 0.0043 16.5 0.1 2.8 7.3 0.0 2.5 3 0 0 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) Tannase PF07519.6 ETO06754.1 - 0.0047 15.7 0.1 0.12 11.1 0.0 2.0 2 0 0 2 2 2 1 Tannase and feruloyl esterase Abhydrolase_2 PF02230.11 ETO06754.1 - 0.0048 16.3 0.1 1.9 7.8 0.0 2.4 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.5 ETO06754.1 - 0.013 15.4 0.0 0.029 14.2 0.0 1.6 1 1 0 1 1 1 0 TAP-like protein PhoPQ_related PF10142.4 ETO06754.1 - 0.015 13.8 0.0 0.017 13.6 0.0 1.1 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Esterase PF00756.15 ETO06754.1 - 0.04 13.3 0.1 0.047 13.1 0.1 1.3 1 1 0 1 1 1 0 Putative esterase BAAT_C PF08840.6 ETO06754.1 - 0.099 12.3 0.2 0.45 10.1 0.1 1.9 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal RtcB PF01139.12 ETO06755.1 - 1.8e-52 178.7 0.0 2.2e-52 178.5 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB zf-C3HC4_3 PF13920.1 ETO06756.1 - 4.9e-11 42.1 8.5 4.9e-11 42.1 5.9 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Gly_transf_sug PF04488.10 ETO06756.1 - 6.9e-08 32.8 7.7 1.3e-07 31.9 0.1 3.6 2 1 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif zf-C3HC4_2 PF13923.1 ETO06756.1 - 1e-05 25.4 9.5 1e-05 25.4 6.6 3.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 ETO06756.1 - 0.011 15.2 3.3 0.011 15.2 2.3 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C2H2 PF00096.21 ETO06757.1 - 0.00052 20.1 2.0 0.00052 20.1 1.4 3.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETO06757.1 - 0.00096 19.3 0.2 0.00096 19.3 0.1 5.7 6 1 0 6 6 6 2 Zinc-finger double domain TFIIS_C PF01096.13 ETO06757.1 - 0.0032 17.0 5.3 0.66 9.6 0.0 3.0 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) zf-C2H2_4 PF13894.1 ETO06757.1 - 0.015 15.6 1.6 0.015 15.6 1.1 3.9 3 1 0 3 3 3 0 C2H2-type zinc finger Ogr_Delta PF04606.7 ETO06757.1 - 0.079 12.6 4.2 1.2 8.7 0.6 2.9 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Zn-ribbon_8 PF09723.5 ETO06757.1 - 0.6 10.0 10.1 1.3 9.0 0.8 3.4 3 0 0 3 3 3 0 Zinc ribbon domain DUF3847 PF12958.2 ETO06757.1 - 4.2 7.2 14.7 0.36 10.6 6.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) FKBP_N PF01346.13 ETO06757.1 - 8.9 6.3 9.1 16 5.5 6.3 1.4 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase AIF_C PF14721.1 ETO06758.1 - 1.6 8.9 4.8 1.2 9.3 0.2 2.2 1 1 1 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF3439 PF11921.3 ETO06758.1 - 2.7 7.7 13.0 4.9 6.9 9.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) WD40 PF00400.27 ETO06759.1 - 0.003 17.3 18.5 3.2 7.7 0.9 6.9 8 0 0 8 8 8 3 WD domain, G-beta repeat DUF3336 PF11815.3 ETO06760.1 - 3.1e-07 29.9 0.5 4.6e-07 29.4 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Cyd_oper_YbgE PF09600.5 ETO06760.1 - 0.034 14.3 1.6 0.72 10.0 0.6 2.5 2 0 0 2 2 2 0 Cyd operon protein YbgE (Cyd_oper_YbgE) Patatin PF01734.17 ETO06761.1 - 1.1e-15 58.1 2.1 5.6e-11 42.7 0.0 2.9 3 0 0 3 3 3 2 Patatin-like phospholipase DUF3336 PF11815.3 ETO06761.1 - 1.5e-09 37.5 0.3 3.3e-09 36.3 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) SSP160 PF06933.6 ETO06761.1 - 3.1 5.6 10.5 4.7 5.0 7.3 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Zip PF02535.17 ETO06761.1 - 8.4 5.2 9.4 5.6 5.8 2.0 2.5 2 0 0 2 2 2 0 ZIP Zinc transporter Metallophos PF00149.23 ETO06762.1 - 5e-35 120.7 0.2 5e-35 120.7 0.1 2.7 3 1 0 3 3 3 1 Calcineurin-like phosphoesterase G-alpha PF00503.15 ETO06764.1 - 4.3e-33 114.5 7.1 1.7e-25 89.5 1.2 2.1 2 0 0 2 2 2 2 G-protein alpha subunit Arf PF00025.16 ETO06764.1 - 1.1e-06 28.0 0.1 0.0038 16.4 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Arch_ATPase PF01637.13 ETO06764.1 - 0.021 14.5 1.1 0.028 14.1 0.2 1.6 2 0 0 2 2 2 0 Archaeal ATPase ABC_tran PF00005.22 ETO06764.1 - 0.037 14.3 0.0 0.058 13.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Miro PF08477.8 ETO06764.1 - 0.082 13.4 1.0 0.21 12.0 0.1 2.2 3 0 0 3 3 3 0 Miro-like protein JAB PF01398.16 ETO06764.1 - 0.089 12.5 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease AAA_29 PF13555.1 ETO06764.1 - 0.12 11.8 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 ETO06764.1 - 0.13 12.2 0.1 0.53 10.2 0.0 2.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase Ribophorin_II PF05817.9 ETO06765.1 - 2.6e-38 131.6 3.1 4e-38 131.0 2.2 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II DUF4636 PF15468.1 ETO06766.1 - 0.037 13.4 2.8 0.059 12.8 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) UPF0029 PF01205.14 ETO06766.1 - 0.052 13.2 0.1 0.1 12.2 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein family UPF0029 zf-TRAF PF02176.13 ETO06767.1 - 6.4e-06 26.4 1.6 6.4e-06 26.4 1.1 2.9 3 0 0 3 3 3 1 TRAF-type zinc finger zf-H2C2_5 PF13909.1 ETO06767.1 - 0.048 13.8 4.3 12 6.3 0.1 4.2 3 1 1 4 4 4 0 C2H2-type zinc-finger domain zf-C3HC4_2 PF13923.1 ETO06767.1 - 8.7 6.4 13.1 0.48 10.4 1.3 3.7 2 2 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Arc_PepC_II PF06847.6 ETO06769.1 - 0.022 15.1 1.3 0.14 12.5 0.0 3.0 3 0 0 3 3 3 0 Archaeal Peptidase A24 C-terminus Type II SET PF00856.23 ETO06770.1 - 1.7e-07 31.6 0.4 1.7e-05 25.1 0.1 3.3 2 1 0 2 2 2 1 SET domain Chromo PF00385.19 ETO06770.1 - 6.4e-06 25.7 0.2 2.1e-05 24.1 0.1 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 ETO06770.1 - 0.2 11.3 6.5 0.65 9.7 4.5 2.0 1 0 0 1 1 1 0 PHD-finger SNF2_N PF00176.18 ETO06771.1 - 5.6e-45 153.4 8.8 3.4e-34 118.0 3.1 2.6 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 ETO06771.1 - 5.2e-16 58.2 0.0 1.6e-15 56.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETO06771.1 - 0.0019 17.7 0.7 0.03 13.8 0.0 2.8 2 1 1 3 3 3 1 DEAD/DEAH box helicase DUF3439 PF11921.3 ETO06771.1 - 2.1 8.0 14.7 0.093 12.4 3.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Rhabdo_ncap PF00945.13 ETO06772.1 - 0.038 12.5 6.1 0.043 12.3 4.2 1.0 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein MIP-T3 PF10243.4 ETO06772.1 - 0.12 10.8 21.4 0.12 10.8 14.9 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 FLO_LFY PF01698.11 ETO06772.1 - 0.12 11.1 11.2 0.13 11.1 7.8 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein U79_P34 PF03064.11 ETO06772.1 - 0.18 11.2 14.4 0.2 11.1 10.0 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Pox_Ag35 PF03286.9 ETO06772.1 - 0.29 10.6 19.8 0.32 10.5 13.7 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF1510 PF07423.6 ETO06772.1 - 0.4 10.0 19.9 0.41 9.9 13.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Vfa1 PF08432.5 ETO06772.1 - 0.5 10.3 21.8 0.55 10.2 15.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 GAGA_bind PF06217.7 ETO06772.1 - 0.65 9.9 15.5 0.69 9.8 10.7 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family DDHD PF02862.12 ETO06772.1 - 1.4 8.6 10.3 1.6 8.4 7.1 1.1 1 0 0 1 1 1 0 DDHD domain RNA_polI_A34 PF08208.6 ETO06772.1 - 3.3 7.3 31.7 3.6 7.1 22.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 EIIBC-GUT_N PF03612.9 ETO06772.1 - 3.7 7.1 7.9 4.4 6.8 5.5 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus AIF_C PF14721.1 ETO06772.1 - 8.4 6.6 8.9 11 6.3 6.2 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term RR_TM4-6 PF06459.7 ETO06772.1 - 8.5 6.1 15.3 9 6.0 10.6 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.3 ETO06772.1 - 9.5 4.7 14.2 9.7 4.6 9.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Pal1 PF08316.6 ETO06773.1 - 0.071 13.5 6.9 1.3 9.5 4.8 2.1 1 1 0 1 1 1 0 Pal1 cell morphology protein BAF1_ABF1 PF04684.8 ETO06773.1 - 0.19 10.5 5.7 0.3 9.9 4.0 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CDK5_activator PF03261.10 ETO06773.1 - 1.7 7.8 12.4 2.1 7.6 8.6 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Suf PF05843.9 ETO06773.1 - 6.7 6.3 9.0 7.3 6.2 6.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) WD40 PF00400.27 ETO06774.1 - 4.6e-75 245.0 20.2 1.2e-12 47.2 0.1 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO06774.1 - 8.5e-08 30.7 7.5 0.084 10.9 0.2 5.0 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Kelch_4 PF13418.1 ETO06774.1 - 1.3e-07 31.2 2.4 8e-06 25.5 0.0 3.9 4 0 0 4 4 4 1 Galactose oxidase, central domain Nucleoporin_N PF08801.6 ETO06774.1 - 4.3e-07 29.0 8.0 0.21 10.3 0.2 4.8 1 1 3 4 4 4 4 Nup133 N terminal like Kelch_6 PF13964.1 ETO06774.1 - 4.8e-07 29.6 12.3 0.0084 16.2 0.4 6.5 8 0 0 8 8 6 2 Kelch motif Cytochrom_D1 PF02239.11 ETO06774.1 - 8.1e-07 27.6 0.1 0.0018 16.6 0.0 3.4 2 2 2 4 4 4 2 Cytochrome D1 heme domain Kelch_2 PF07646.10 ETO06774.1 - 3.9e-05 23.2 3.4 0.017 14.9 0.4 4.7 4 0 0 4 4 4 1 Kelch motif PD40 PF07676.7 ETO06774.1 - 0.00011 21.7 6.0 1.3 8.8 0.0 5.1 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO06774.1 - 0.0002 20.9 0.3 0.002 17.6 0.2 2.4 1 1 0 1 1 1 1 PQQ-like domain Nbas_N PF15492.1 ETO06774.1 - 0.00024 20.3 1.2 0.12 11.4 0.1 3.5 1 1 2 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Kelch_5 PF13854.1 ETO06774.1 - 0.00047 20.0 4.1 0.36 10.8 0.4 4.3 4 0 0 4 4 4 1 Kelch motif Ricin_B_lectin PF00652.17 ETO06774.1 - 0.00081 19.4 6.4 0.35 10.9 0.4 3.9 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain Hira PF07569.6 ETO06774.1 - 0.0029 16.8 0.5 13 4.9 0.0 4.5 5 0 0 5 5 5 0 TUP1-like enhancer of split Resistin PF06954.6 ETO06774.1 - 0.003 17.8 0.7 6 7.2 0.0 3.7 2 1 1 3 3 3 1 Resistin Kelch_3 PF13415.1 ETO06774.1 - 0.096 12.8 0.4 2.4 8.4 0.0 3.4 4 0 0 4 4 3 0 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO06774.1 - 0.11 12.1 4.9 3.7 7.1 0.5 3.7 4 0 0 4 4 4 0 Kelch motif Proteasome_A_N PF10584.4 ETO06774.1 - 2.3 7.6 12.4 1.5 8.2 0.0 4.4 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature MFS_1 PF07690.11 ETO06775.1 - 2.9e-20 72.2 3.1 4.5e-20 71.6 2.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETO06775.1 - 8.3e-05 21.3 3.7 8.3e-05 21.3 2.6 2.1 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 ETO06775.1 - 0.00011 20.4 4.4 0.0002 19.6 3.1 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector cNMP_binding PF00027.24 ETO06776.1 - 8.9e-25 86.3 0.0 1.3e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Cupin_2 PF07883.6 ETO06776.1 - 0.055 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Cupin domain SpoIIIAH PF12685.2 ETO06776.1 - 4.7 6.6 13.0 8.2 5.8 9.0 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein TFIID-31kDa PF02291.10 ETO06777.1 - 3.5e-15 55.9 0.4 5.9e-15 55.2 0.3 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit TFIID_20kDa PF03847.8 ETO06777.1 - 0.00084 19.5 0.4 0.0015 18.7 0.3 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TFIID-18kDa PF02269.11 ETO06777.1 - 0.0017 18.1 0.1 0.0032 17.2 0.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CRAL_TRIO PF00650.15 ETO06777.1 - 0.0042 16.5 0.3 0.0072 15.8 0.2 1.5 1 1 0 1 1 1 1 CRAL/TRIO domain Histone PF00125.19 ETO06777.1 - 0.025 14.7 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 PHD PF00628.24 ETO06778.1 - 9.4e-10 38.0 5.0 2e-09 36.9 3.4 1.6 1 0 0 1 1 1 1 PHD-finger End3 PF12761.2 ETO06778.1 - 2.5 7.6 20.7 0.064 12.8 8.7 2.0 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 RabGAP-TBC PF00566.13 ETO06779.1 - 3.3e-25 88.8 2.9 7.8e-14 51.6 0.2 6.5 4 2 1 5 5 5 2 Rab-GTPase-TBC domain Secretin_N_2 PF07655.8 ETO06779.1 - 0.00094 19.5 15.2 0.00094 19.5 10.5 6.6 7 0 0 7 7 7 4 Secretin N-terminal domain PH PF00169.24 ETO06780.1 - 7e-11 42.2 0.3 1.1e-10 41.6 0.2 1.3 1 0 0 1 1 1 1 PH domain RhoGEF PF00621.15 ETO06780.1 - 0.014 15.3 1.3 0.24 11.2 0.0 2.3 2 1 0 2 2 2 0 RhoGEF domain PH_11 PF15413.1 ETO06780.1 - 0.037 14.2 0.1 0.087 13.0 0.0 1.8 1 1 1 2 2 2 0 Pleckstrin homology domain V-SNARE PF05008.10 ETO06780.1 - 0.13 12.4 0.2 1.6 8.9 0.1 2.4 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF3810 PF12725.2 ETO06781.1 - 0.016 14.0 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Radial_spoke PF04712.7 ETO06782.1 - 0.0042 15.9 2.7 0.0042 15.9 1.9 2.0 2 0 0 2 2 2 1 Radial spokehead-like protein DUF3381 PF11861.3 ETO06782.1 - 0.0059 16.1 5.3 0.0059 16.1 3.7 2.9 2 1 0 3 3 3 1 Domain of unknown function (DUF3381) DUF4632 PF15451.1 ETO06782.1 - 0.012 15.5 0.1 0.03 14.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) DUF4611 PF15387.1 ETO06782.1 - 0.23 11.6 6.0 0.41 10.8 1.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Pex16 PF08610.5 ETO06783.1 - 1.8 7.4 8.5 0.24 10.3 2.2 2.1 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) ERCC4 PF02732.10 ETO06785.1 - 3.5e-15 55.9 0.3 5.6e-15 55.3 0.2 1.3 1 0 0 1 1 1 1 ERCC4 domain Gemini_coat PF00844.13 ETO06785.1 - 0.67 9.1 3.5 4.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Geminivirus coat protein/nuclear export factor BR1 family NST1 PF13945.1 ETO06785.1 - 0.74 9.8 7.1 1.4 8.9 4.9 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator BLVR PF06375.6 ETO06785.1 - 2.2 8.0 7.1 3.5 7.4 4.9 1.4 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) G-alpha PF00503.15 ETO06786.1 - 1.2e-28 99.8 3.0 1.4e-28 99.7 2.1 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Cu_bind_like PF02298.12 ETO06786.1 - 0.024 14.4 1.1 0.038 13.7 0.1 1.9 2 0 0 2 2 2 0 Plastocyanin-like domain FSH1 PF03959.8 ETO06787.1 - 3.3e-33 114.9 0.7 3.3e-32 111.6 0.5 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 ETO06787.1 - 0.0068 16.1 0.0 0.0094 15.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETO06787.1 - 0.012 15.4 0.0 0.089 12.6 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family Rad17 PF03215.10 ETO06788.1 - 2e-21 76.3 16.6 1.8e-15 56.6 5.9 4.1 2 2 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 ETO06788.1 - 8.8e-06 25.8 0.0 2.1e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 ETO06788.1 - 0.00028 21.0 0.3 0.0018 18.3 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA PF00004.24 ETO06788.1 - 0.00035 20.7 0.0 0.0012 19.0 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETO06788.1 - 0.00039 20.1 0.2 0.0017 18.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETO06788.1 - 0.0021 18.2 0.0 0.0062 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETO06788.1 - 0.0083 15.8 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain ABC_tran PF00005.22 ETO06788.1 - 0.012 15.8 0.0 0.012 15.8 0.0 2.8 3 1 0 3 3 2 0 ABC transporter AAA_18 PF13238.1 ETO06788.1 - 0.051 13.8 5.3 0.11 12.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 ETO06788.1 - 0.064 14.0 0.0 0.33 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 ETO06788.1 - 0.065 13.1 0.0 0.2 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 ETO06788.1 - 0.093 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain CD36 PF01130.16 ETO06789.1 - 5.4e-47 160.1 16.7 2e-46 158.3 11.6 1.9 1 1 0 1 1 1 1 CD36 family Sigma70_ner PF04546.8 ETO06792.1 - 0.019 14.6 4.4 0.019 14.6 3.1 1.5 2 0 0 2 2 2 0 Sigma-70, non-essential region Nop14 PF04147.7 ETO06792.1 - 0.064 11.1 8.9 0.076 10.9 6.2 1.0 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.5 ETO06792.1 - 0.069 13.3 9.3 0.18 12.0 6.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain UPF0560 PF10577.4 ETO06792.1 - 0.14 10.4 3.0 0.15 10.3 2.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 PGA2 PF07543.7 ETO06792.1 - 0.15 11.8 4.9 0.2 11.4 1.3 2.1 2 0 0 2 2 2 0 Protein trafficking PGA2 BTV_NS2 PF04514.7 ETO06792.1 - 0.17 10.7 5.0 0.21 10.4 3.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Bd3614_N PF14442.1 ETO06792.1 - 0.92 9.4 7.8 3.7 7.5 4.8 2.0 2 0 0 2 2 2 0 Bd3614-like deaminase N-terminal NOA36 PF06524.7 ETO06792.1 - 1.1 8.3 7.3 2.1 7.5 5.0 1.4 1 0 0 1 1 1 0 NOA36 protein DUF1754 PF08555.5 ETO06792.1 - 1.5 9.4 8.3 6.6 7.4 0.2 2.2 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) FAM176 PF14851.1 ETO06792.1 - 4.4 6.9 7.2 4 7.0 3.7 1.8 2 0 0 2 2 2 0 FAM176 family PBP1_TM PF14812.1 ETO06792.1 - 5.4 7.3 14.0 1.1 9.6 5.1 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TcdB_N PF12918.2 ETO06794.1 - 0.065 13.3 4.0 1.1 9.3 0.1 2.6 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain DivIC PF04977.10 ETO06794.1 - 5.5 6.5 13.3 0.16 11.4 1.4 3.1 2 1 1 3 3 3 0 Septum formation initiator IDO PF01231.13 ETO06795.1 - 9.5e-25 86.8 0.3 1.7e-23 82.7 0.2 2.2 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase Clat_adaptor_s PF01217.15 ETO06796.1 - 2.3e-52 176.4 2.9 2.6e-52 176.3 2.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain 7tm_3 PF00003.17 ETO06797.1 - 6.4e-19 68.2 24.2 2.5e-18 66.3 16.8 2.0 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Menin PF05053.8 ETO06797.1 - 3.7 5.5 8.5 5.3 5.0 5.9 1.1 1 0 0 1 1 1 0 Menin EGF_2 PF07974.8 ETO06797.1 - 7.2 6.8 17.8 0.055 13.6 6.4 2.0 2 0 0 2 2 2 0 EGF-like domain MFS_1 PF07690.11 ETO06799.1 - 4.2e-10 38.8 15.5 6.8e-10 38.1 10.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1433 PF07252.6 ETO06799.1 - 0.036 14.2 0.0 0.06 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1433) DUF964 PF06133.6 ETO06799.1 - 0.052 13.5 0.3 0.076 13.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF964) Nitroreductase PF00881.19 ETO06799.1 - 0.13 12.0 0.0 11 5.8 0.0 2.2 2 0 0 2 2 2 0 Nitroreductase family Cation_efflux PF01545.16 ETO06799.1 - 3.6 6.5 8.6 11 5.0 5.2 1.9 1 1 1 2 2 2 0 Cation efflux family WD40 PF00400.27 ETO06800.1 - 5e-41 137.1 20.8 8.4e-11 41.3 0.8 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO06800.1 - 3.4e-10 38.6 0.5 0.015 13.4 0.0 4.2 3 1 1 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO06800.1 - 0.0011 17.7 3.5 0.34 9.5 0.5 3.8 3 1 2 5 5 5 3 Nup133 N terminal like DUF3601 PF12208.3 ETO06800.1 - 0.0044 16.9 0.1 0.29 11.0 0.1 3.1 1 1 2 3 3 3 1 Domain of unknown function (DUF3601) UCH PF00443.24 ETO06801.1 - 2.7e-45 154.5 17.6 6e-33 114.0 0.2 3.9 3 2 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 ETO06801.1 - 1.2e-11 44.8 0.0 1.2e-11 44.8 0.0 5.8 5 1 0 5 5 5 1 DUSP domain zf-C2H2_4 PF13894.1 ETO06802.1 - 0.00018 21.5 30.6 0.039 14.2 1.4 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 ETO06802.1 - 0.0074 16.3 1.5 0.0074 16.3 1.0 4.4 2 2 2 4 4 4 1 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.5 ETO06802.1 - 0.018 14.9 9.7 0.62 10.0 0.2 3.8 4 0 0 4 4 4 0 Zinc ribbon domain Lar_restr_allev PF14354.1 ETO06802.1 - 0.025 14.8 2.8 1.2 9.4 0.1 2.6 2 0 0 2 2 2 0 Restriction alleviation protein Lar DUF1764 PF08576.5 ETO06802.1 - 0.025 15.3 17.5 0.025 15.3 12.1 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) DUF4451 PF14616.1 ETO06802.1 - 0.028 14.1 21.4 1.1 9.0 0.1 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4451) zf-C2H2 PF00096.21 ETO06802.1 - 0.045 14.1 3.2 0.045 14.1 2.2 4.6 4 1 0 4 4 3 0 Zinc finger, C2H2 type zf-C2H2_3 PF13878.1 ETO06802.1 - 0.087 12.4 0.6 0.087 12.4 0.4 3.0 3 0 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO zf-Di19 PF05605.7 ETO06802.1 - 0.27 11.3 21.4 2.2 8.4 5.8 3.3 2 2 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF775 PF05603.7 ETO06802.1 - 0.89 9.0 8.1 1.6 8.1 5.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF775) FHIPEP PF00771.15 ETO06802.1 - 1.2 7.3 3.1 1.9 6.6 2.2 1.3 1 0 0 1 1 1 0 FHIPEP family Zn_Tnp_IS1595 PF12760.2 ETO06802.1 - 2.3 8.0 9.3 0.49 10.2 3.1 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain C1_4 PF07975.7 ETO06802.1 - 3.4 7.7 8.1 0.64 10.0 0.8 3.2 3 0 0 3 3 3 0 TFIIH C1-like domain EF-hand_1 PF00036.27 ETO06803.1 - 0.00046 19.2 0.0 0.0011 18.1 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 ETO06803.1 - 0.0007 18.8 0.1 0.0007 18.8 0.1 1.7 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 ETO06803.1 - 0.0074 16.3 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 ETO06803.1 - 0.02 14.4 0.0 0.058 13.0 0.0 1.7 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.1 ETO06803.1 - 0.022 14.6 1.1 0.054 13.4 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain Holin_LLH PF09682.5 ETO06804.1 - 0.031 14.4 0.1 0.082 13.0 0.1 1.7 1 0 0 1 1 1 0 Phage holin protein (Holin_LLH) DUF3439 PF11921.3 ETO06804.1 - 1.1 9.0 20.8 0.62 9.8 7.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF848 PF05852.6 ETO06805.1 - 0.0016 18.2 1.0 0.002 18.0 0.7 1.2 1 0 0 1 1 1 1 Gammaherpesvirus protein of unknown function (DUF848) Nop25 PF09805.4 ETO06805.1 - 0.087 12.8 6.8 0.11 12.6 4.7 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF3452 PF11934.3 ETO06805.1 - 0.09 12.0 2.2 0.11 11.7 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) Menin PF05053.8 ETO06805.1 - 0.09 10.9 2.2 0.1 10.7 1.5 1.0 1 0 0 1 1 1 0 Menin Tox-HDC PF15656.1 ETO06805.1 - 0.12 12.5 4.1 0.18 11.9 2.7 1.5 1 1 0 1 1 1 0 Toxin with a H, D/N and C signature Tsg PF04668.7 ETO06805.1 - 2.7 8.2 6.0 2.2 8.4 3.0 1.6 1 1 1 2 2 2 0 Twisted gastrulation (Tsg) protein conserved region Bap31 PF05529.7 ETO06805.1 - 6.7 6.1 7.8 14 5.1 5.4 1.6 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like U-box PF04564.10 ETO06806.1 - 1.4e-09 37.7 0.1 1.4e-09 37.7 0.1 2.3 2 0 0 2 2 2 1 U-box domain SlyX PF04102.7 ETO06806.1 - 0.81 10.0 7.5 1 9.7 0.3 3.4 3 0 0 3 3 3 0 SlyX DUF1911 PF08929.5 ETO06806.1 - 4.3 8.0 7.9 1.2 9.8 0.4 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1911) TFIIE_alpha PF02002.12 ETO06807.1 - 0.0033 16.9 0.1 0.012 15.1 0.0 1.9 2 0 0 2 2 2 1 TFIIE alpha subunit zf-UBR PF02207.15 ETO06812.1 - 1.8e-10 40.3 11.0 1.8e-10 40.3 7.7 2.0 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) WD40 PF00400.27 ETO06813.1 - 1.5e-13 50.0 0.1 0.0016 18.2 0.0 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Actin PF00022.14 ETO06816.1 - 7.5e-126 419.7 0.0 8.6e-126 419.5 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 ETO06816.1 - 0.025 13.2 0.0 0.044 12.3 0.0 1.3 1 0 0 1 1 1 0 MreB/Mbl protein WD40 PF00400.27 ETO06817.1 - 3.1e-72 236.0 22.8 3.3e-13 48.9 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO06817.1 - 1.9e-10 39.5 8.5 0.072 11.2 0.1 5.1 1 1 2 4 4 4 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO06817.1 - 5.3e-10 39.1 3.8 6.1e-06 25.8 0.5 3.2 1 1 2 3 3 3 3 PQQ-like domain Cytochrom_D1 PF02239.11 ETO06817.1 - 2.1e-07 29.5 4.0 0.00011 20.6 0.2 2.9 1 1 1 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO06817.1 - 2e-06 26.8 16.2 0.044 12.5 1.1 5.0 1 1 3 4 4 4 4 Nup133 N terminal like PQQ PF01011.16 ETO06817.1 - 8.8e-05 21.8 0.4 15 5.3 0.0 5.1 5 0 0 5 5 5 0 PQQ enzyme repeat Biotin_lipoyl_2 PF13533.1 ETO06817.1 - 0.00076 19.0 0.1 0.67 9.6 0.0 3.0 2 0 0 2 2 2 2 Biotin-lipoyl like Hira PF07569.6 ETO06817.1 - 0.0014 17.9 1.5 0.69 9.0 0.0 4.2 2 2 2 4 4 4 1 TUP1-like enhancer of split BBS2_Mid PF14783.1 ETO06817.1 - 0.014 15.1 8.1 6.8 6.5 0.1 5.0 1 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region PD40 PF07676.7 ETO06817.1 - 0.041 13.5 9.0 34 4.2 0.0 5.8 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat DUF2149 PF09919.4 ETO06817.1 - 0.07 13.2 1.1 12 6.1 0.1 4.1 3 1 2 5 5 5 0 Uncharacterized conserved protein (DUF2149) BRX PF08381.6 ETO06817.1 - 0.1 11.6 0.3 1 8.4 0.1 2.6 2 0 0 2 2 2 0 Transcription factor regulating root and shoot growth via Pin3 Proteasome_A_N PF10584.4 ETO06817.1 - 2.1 7.7 4.2 53 3.2 0.1 4.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Exo_endo_phos_2 PF14529.1 ETO06818.1 - 5.6e-20 71.1 1.4 1.4e-19 69.8 1.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 ETO06818.1 - 8.4e-06 25.2 0.2 2e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3599 PF12206.3 ETO06818.1 - 0.027 14.7 0.2 0.48 10.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3599) POLO_box PF00659.13 ETO06819.1 - 1.2e-31 108.5 8.2 6.3e-19 67.7 0.1 2.4 2 0 0 2 2 2 2 POLO box duplicated region CENP-B_dimeris PF09026.5 ETO06819.1 - 0.014 15.6 0.6 0.028 14.6 0.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Actino_peptide PF14408.1 ETO06819.1 - 0.11 12.4 0.0 2.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Ribosomally synthesized peptide in actinomycetes PAXIP1_C PF15364.1 ETO06819.1 - 1.8 8.4 11.4 0.13 12.1 4.4 1.7 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein GDC-P PF02347.11 ETO06820.1 - 1.6e-64 218.2 0.1 1.7e-64 218.0 0.1 1.0 1 0 0 1 1 1 1 Glycine cleavage system P-protein WHG PF13305.1 ETO06820.1 - 0.12 13.0 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 WHG domain Med11 PF10280.4 ETO06821.1 - 8 6.5 12.2 3.5 7.7 1.1 3.9 3 3 0 3 3 3 0 Mediator complex protein ERAP1_C PF11838.3 ETO06822.1 - 0.042 13.1 0.5 0.38 9.9 0.3 1.9 1 1 0 1 1 1 0 ERAP1-like C-terminal domain SDA1 PF05285.7 ETO06823.1 - 0.00037 19.8 21.0 0.00056 19.3 14.6 1.2 1 0 0 1 1 1 1 SDA1 Tim54 PF11711.3 ETO06823.1 - 1.1 7.8 7.0 0.6 8.6 1.4 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.9 ETO06823.1 - 3.1 5.7 28.5 5.9 4.7 19.7 1.5 1 1 0 1 1 1 0 CDC45-like protein Nop25 PF09805.4 ETO06823.1 - 7.8 6.5 22.5 1.6 8.8 7.7 2.3 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) PH PF00169.24 ETO06825.1 - 0.0022 18.1 13.5 0.086 13.0 2.8 3.8 3 1 0 3 3 3 2 PH domain PH_11 PF15413.1 ETO06825.1 - 0.0073 16.5 6.1 0.026 14.7 2.0 3.3 2 1 0 2 2 2 1 Pleckstrin homology domain Menin PF05053.8 ETO06825.1 - 5.5 5.0 10.9 11 4.0 7.6 1.4 1 0 0 1 1 1 0 Menin Mito_carr PF00153.22 ETO06828.1 - 3.2e-17 62.0 0.4 5.3e-08 32.4 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Mucin PF01456.12 ETO06830.1 - 0.0017 18.1 4.7 0.0017 18.1 3.2 1.5 2 0 0 2 2 2 1 Mucin-like glycoprotein Ashwin PF15323.1 ETO06830.1 - 0.031 14.2 4.1 0.041 13.8 2.9 1.3 1 0 0 1 1 1 0 Developmental protein DUF3439 PF11921.3 ETO06830.1 - 0.37 10.5 7.8 0.73 9.5 5.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Herpes_capsid PF06112.6 ETO06830.1 - 1.1 9.3 5.8 1.8 8.6 4.0 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein SSP160 PF06933.6 ETO06830.1 - 2.2 6.1 11.7 3 5.7 8.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF929 PF06053.6 ETO06831.1 - 0.097 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF929) SUKH_6 PF14568.1 ETO06831.1 - 0.1 13.1 0.6 0.14 12.5 0.4 1.3 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall PIRT PF15099.1 ETO06832.1 - 0.00056 19.1 0.4 0.0017 17.5 0.1 1.9 2 0 0 2 2 2 1 Phosphoinositide-interacting protein family TM_helix PF05552.7 ETO06832.1 - 0.21 11.2 3.9 0.51 10.0 2.7 1.6 1 0 0 1 1 1 0 Conserved TM helix Chitin_synth_2 PF03142.10 ETO06832.1 - 1.1 7.5 5.8 2 6.7 4.0 1.3 1 0 0 1 1 1 0 Chitin synthase Vpu PF00558.14 ETO06832.1 - 1.5 8.3 4.0 0.41 10.2 0.1 2.1 2 0 0 2 2 2 0 Vpu protein Exo_endo_phos PF03372.18 ETO06833.1 - 0.0027 17.6 0.0 0.0058 16.6 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 ETO06834.1 - 0.043 13.4 0.0 0.55 9.8 0.0 2.5 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase TPR_11 PF13414.1 ETO06835.1 - 2.8e-28 97.3 35.3 3.5e-12 45.7 4.3 3.9 1 1 3 4 4 4 4 TPR repeat TPR_17 PF13431.1 ETO06835.1 - 1.7e-15 55.8 19.6 7.1e-05 22.6 1.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO06835.1 - 3.6e-13 48.8 6.1 0.02 15.4 0.0 4.2 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO06835.1 - 2.6e-12 47.0 14.9 1.4e-06 28.7 1.9 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 ETO06835.1 - 9.5e-12 44.6 27.8 1.1e-06 28.4 5.4 3.4 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO06835.1 - 1.1e-11 43.6 24.7 0.0041 16.9 0.3 5.5 4 2 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO06835.1 - 6.3e-11 41.4 25.4 0.00075 18.9 2.2 5.8 3 2 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO06835.1 - 8.8e-11 41.9 12.5 0.00012 22.3 2.1 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO06835.1 - 7.1e-10 37.9 20.1 0.004 16.8 2.0 5.0 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO06835.1 - 2.5e-05 24.4 6.4 5.1 7.7 0.2 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETO06835.1 - 0.00032 20.5 5.0 0.0026 17.5 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO06835.1 - 0.00065 19.3 9.8 3.1 7.8 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat eIF-3c_N PF05470.7 ETO06835.1 - 0.0027 15.8 2.9 0.0037 15.4 2.0 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus FAT PF02259.18 ETO06835.1 - 0.025 13.5 7.7 0.6 9.0 2.5 2.7 1 1 1 2 2 2 0 FAT domain Fis1_TPR_C PF14853.1 ETO06835.1 - 0.033 14.0 5.2 0.26 11.1 0.1 3.3 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat MitMem_reg PF13012.1 ETO06835.1 - 1.8 8.6 6.8 0.26 11.3 0.3 2.6 2 1 1 3 3 3 0 Maintenance of mitochondrial structure and function SNAP PF14938.1 ETO06835.1 - 1.9 7.5 11.0 1.1e+02 1.8 3.9 2.3 1 1 0 1 1 1 0 Soluble NSF attachment protein, SNAP Uds1 PF15456.1 ETO06836.1 - 0.00021 21.2 4.0 0.00021 21.2 2.7 1.7 2 0 0 2 2 2 1 Up-regulated During Septation SpoIIIAH PF12685.2 ETO06836.1 - 0.0032 16.9 6.0 0.0051 16.3 4.1 1.3 1 0 0 1 1 1 1 SpoIIIAH-like protein DUF2457 PF10446.4 ETO06836.1 - 0.0041 15.9 16.0 0.0041 15.9 11.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) PBP1_TM PF14812.1 ETO06836.1 - 0.029 14.6 10.6 0.029 14.6 7.4 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mpp10 PF04006.7 ETO06836.1 - 0.11 10.8 13.1 0.17 10.1 9.1 1.3 1 0 0 1 1 1 0 Mpp10 protein Sigma70_ner PF04546.8 ETO06836.1 - 0.27 10.8 11.2 0.075 12.6 5.2 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region HSP90 PF00183.13 ETO06836.1 - 0.33 9.2 11.5 0.43 8.9 8.0 1.2 1 0 0 1 1 1 0 Hsp90 protein ELH PF02323.10 ETO06836.1 - 1.4 7.9 6.1 7.8 5.5 0.1 2.1 2 0 0 2 2 2 0 Egg-laying hormone precursor Cwf_Cwc_15 PF04889.7 ETO06836.1 - 1.7 8.2 18.3 2.5 7.7 10.5 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CCDC74_C PF14917.1 ETO06836.1 - 1.8 8.6 4.9 0.54 10.3 1.4 1.7 2 0 0 2 2 2 0 Coiled coil protein 74, C terminal Striatin PF08232.7 ETO06836.1 - 2.5 8.4 10.6 5.9 7.1 4.3 2.2 2 0 0 2 2 2 0 Striatin family Nucleoplasmin PF03066.10 ETO06836.1 - 2.7 7.4 14.1 2.1 7.8 7.7 2.1 2 0 0 2 2 2 0 Nucleoplasmin GCIP PF13324.1 ETO06836.1 - 5.7 6.0 6.7 11 5.0 4.6 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting POX PF07526.6 ETO06836.1 - 6.9 6.9 9.1 19 5.4 2.6 2.2 2 0 0 2 2 2 0 Associated with HOX Secretin_N_2 PF07655.8 ETO06836.1 - 7.3 7.0 9.9 6.5 7.2 0.6 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain FadA PF09403.5 ETO06838.1 - 0.0013 18.7 19.5 0.0028 17.6 8.1 2.5 2 0 0 2 2 2 1 Adhesion protein FadA Filament PF00038.16 ETO06838.1 - 0.0091 15.4 33.8 0.013 14.9 5.5 2.2 1 1 1 2 2 2 1 Intermediate filament protein Pex19 PF04614.7 ETO06838.1 - 0.018 14.6 30.1 0.061 12.9 3.3 2.2 1 1 1 2 2 2 0 Pex19 protein family UvrD_C_2 PF13538.1 ETO06838.1 - 0.072 13.2 2.0 0.13 12.3 0.2 2.3 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain Reo_sigmaC PF04582.7 ETO06838.1 - 0.1 11.7 20.9 0.16 11.1 5.1 2.3 1 1 0 2 2 2 0 Reovirus sigma C capsid protein WXG100 PF06013.7 ETO06838.1 - 0.11 12.4 20.7 0.084 12.8 1.5 4.4 2 2 1 3 3 3 0 Proteins of 100 residues with WXG Stanniocalcin PF03298.8 ETO06838.1 - 0.17 10.8 6.4 0.036 13.0 0.9 2.2 1 1 1 2 2 2 0 Stanniocalcin family TetR PF13972.1 ETO06838.1 - 0.19 11.1 10.7 0.028 13.8 2.4 3.0 2 2 1 3 3 3 0 Bacterial transcriptional repressor DUF3584 PF12128.3 ETO06838.1 - 0.2 8.9 30.2 0.28 8.4 20.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.7 ETO06838.1 - 0.2 11.4 28.5 3.3 7.5 8.4 3.4 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus LXG PF04740.7 ETO06838.1 - 0.26 11.0 32.3 0.26 11.0 10.4 3.0 1 1 1 2 2 2 0 LXG domain of WXG superfamily FTCD_C PF04961.7 ETO06838.1 - 0.39 10.1 11.5 0.047 13.1 2.8 2.6 1 1 1 3 3 3 0 Formiminotransferase-cyclodeaminase KfrA_N PF11740.3 ETO06838.1 - 0.42 11.0 10.4 0.47 10.9 0.8 3.1 1 1 2 3 3 3 0 Plasmid replication region DNA-binding N-term DUF883 PF05957.8 ETO06838.1 - 0.43 11.0 13.3 15 6.0 0.7 3.8 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF883) CR6_interact PF10147.4 ETO06838.1 - 0.53 9.5 13.8 0.09 12.0 5.4 2.2 2 0 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 OmpH PF03938.9 ETO06838.1 - 1.2 9.0 35.7 1.6 8.6 9.9 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) PEP-utilisers_N PF05524.8 ETO06838.1 - 1.9 8.2 12.9 3.1 7.6 0.5 3.3 2 1 1 3 3 3 0 PEP-utilising enzyme, N-terminal IncA PF04156.9 ETO06838.1 - 2.3 7.7 37.7 5.1 6.6 13.5 2.4 1 1 1 2 2 2 0 IncA protein Syntaxin-6_N PF09177.6 ETO06838.1 - 4.2 7.8 25.2 18 5.7 7.3 3.6 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DHquinase_II PF01220.14 ETO06838.1 - 4.3 6.6 12.1 2.7 7.3 1.6 2.8 1 1 1 3 3 3 0 Dehydroquinase class II MRP-L47 PF06984.8 ETO06838.1 - 4.4 7.2 11.5 0.32 10.9 0.2 3.4 1 1 2 3 3 3 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) GUCT PF08152.7 ETO06838.1 - 6.1 6.9 9.2 4 7.4 1.3 3.1 1 1 1 3 3 3 0 GUCT (NUC152) domain Fib_alpha PF08702.5 ETO06838.1 - 6.3 6.9 34.8 2.3 8.3 11.0 3.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family COG5 PF10392.4 ETO06838.1 - 8.2 6.4 32.5 0.1 12.5 6.2 3.2 1 1 1 2 2 2 0 Golgi transport complex subunit 5 NusB PF01029.13 ETO06838.1 - 9.5 6.2 14.0 1.4 8.8 3.2 3.0 1 1 3 4 4 4 0 NusB family Nucleoplasmin PF03066.10 ETO06839.1 - 0.11 12.0 7.4 0.17 11.3 5.2 1.4 1 0 0 1 1 1 0 Nucleoplasmin Prothymosin PF03247.9 ETO06839.1 - 0.65 10.1 21.4 0.12 12.4 8.0 2.4 3 0 0 3 3 3 0 Prothymosin/parathymosin family BTV_NS2 PF04514.7 ETO06839.1 - 0.84 8.4 9.8 0.36 9.6 5.1 1.5 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 CENP-B_dimeris PF09026.5 ETO06839.1 - 0.92 9.7 9.7 2.3 8.4 6.7 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 ETO06839.1 - 1.2 9.4 9.2 2.6 8.4 6.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Kinesin PF00225.18 ETO06840.1 - 2.4e-07 29.8 0.2 2.9e-07 29.4 0.1 1.1 1 0 0 1 1 1 1 Kinesin motor domain Rib PF08428.5 ETO06840.1 - 0.061 13.0 0.1 0.061 13.0 0.1 1.7 2 0 0 2 2 2 0 Rib/alpha-like repeat Zip PF02535.17 ETO06843.1 - 0.0024 16.9 5.6 0.0033 16.5 3.9 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter AalphaY_MDB PF04611.7 ETO06843.1 - 0.025 14.4 0.2 0.073 12.9 0.1 1.9 2 0 0 2 2 2 0 Mating type protein A alpha Y mating type dependent binding region Innate_immun PF12782.2 ETO06843.1 - 0.075 12.2 14.3 0.11 11.6 9.9 1.2 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family SelP_N PF04592.9 ETO06843.1 - 1.8 7.9 14.4 3 7.1 10.0 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PNP_UDP_1 PF01048.15 ETO06844.1 - 7.5e-14 51.2 0.0 1.5e-13 50.3 0.0 1.6 2 0 0 2 2 2 1 Phosphorylase superfamily Proteasome PF00227.21 ETO06847.1 - 3.3e-21 75.4 2.0 2.7e-19 69.1 0.4 2.5 2 1 0 2 2 2 1 Proteasome subunit Mesd PF10185.4 ETO06847.1 - 0.0011 18.6 1.8 0.002 17.8 1.2 1.4 1 0 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor DUF1068 PF06364.7 ETO06847.1 - 0.17 11.4 3.8 0.39 10.3 2.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1068) Ribosomal_S13 PF00416.17 ETO06847.1 - 7.8 7.0 7.8 1.9 8.9 2.4 2.1 2 1 1 3 3 3 0 Ribosomal protein S13/S18 Ras PF00071.17 ETO06848.1 - 7e-20 71.0 0.3 9.1e-20 70.6 0.2 1.1 1 0 0 1 1 1 1 Ras family Hpre_diP_synt_I PF07456.6 ETO06848.1 - 0.086 12.6 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase component I MIP-T3 PF10243.4 ETO06851.1 - 3.9e-05 22.3 41.2 3.9e-05 22.3 28.5 3.4 3 1 0 3 3 3 1 Microtubule-binding protein MIP-T3 Borrelia_P83 PF05262.6 ETO06851.1 - 0.13 10.4 37.3 0.0032 15.7 19.0 2.1 2 0 0 2 2 2 0 Borrelia P83/100 protein Exo_endo_phos PF03372.18 ETO06852.1 - 1.7e-07 31.4 0.0 7.9e-07 29.2 0.0 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family eIF2_C PF09173.6 ETO06853.1 - 0.0088 16.0 2.2 0.12 12.3 1.6 2.1 1 1 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal DUF3496 PF12001.3 ETO06853.1 - 0.035 14.3 1.2 0.057 13.6 0.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3496) RVT_N PF13655.1 ETO06853.1 - 0.058 13.4 4.2 0.11 12.5 2.9 1.6 1 1 0 1 1 1 0 N-terminal domain of reverse transcriptase Asparaginase PF00710.15 ETO06855.1 - 2.5e-70 236.8 0.0 5.4e-52 176.6 0.0 3.4 3 1 1 4 4 4 3 Asparaginase WD40 PF00400.27 ETO06857.1 - 1e-78 256.6 16.7 1.3e-11 43.8 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO06857.1 - 2.5e-16 59.9 2.3 7.3e-07 29.0 0.1 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO06857.1 - 1.2e-08 33.5 11.4 0.13 10.4 0.4 6.3 1 1 4 5 5 5 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO06857.1 - 4.4e-06 26.3 8.8 0.00047 19.6 0.9 2.5 1 1 1 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 ETO06857.1 - 1.6e-05 23.8 10.9 0.06 12.0 0.8 5.2 1 1 4 5 5 5 2 Nup133 N terminal like Hira PF07569.6 ETO06857.1 - 5.2e-05 22.5 1.2 0.21 10.7 0.0 3.9 1 1 3 4 4 4 2 TUP1-like enhancer of split Glyco_hydro_26 PF02156.10 ETO06857.1 - 0.00032 20.2 0.3 0.0056 16.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 26 PD40 PF07676.7 ETO06857.1 - 0.00037 20.0 4.0 0.4 10.3 0.1 5.2 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO06857.1 - 0.00037 20.6 0.5 6.5 7.1 0.0 4.1 2 2 1 3 3 3 1 Resistin Cytochrom_D1 PF02239.11 ETO06857.1 - 0.0027 16.0 0.6 3.1 6.0 0.0 2.9 1 1 2 3 3 3 2 Cytochrome D1 heme domain B_lectin PF01453.19 ETO06857.1 - 0.0053 16.6 0.8 0.19 11.6 0.1 2.5 2 0 0 2 2 2 1 D-mannose binding lectin DPPIV_N PF00930.16 ETO06857.1 - 0.0077 14.8 0.1 3.1 6.2 0.0 3.4 1 1 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF3732 PF12532.3 ETO06857.1 - 0.12 11.8 1.8 9.5 5.6 0.0 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF3732) AzlD PF05437.7 ETO06858.1 - 0.012 15.5 3.0 0.012 15.5 2.1 1.8 2 0 0 2 2 2 0 Branched-chain amino acid transport protein (AzlD) NACHT PF05729.7 ETO06859.1 - 7.5e-08 32.1 0.0 1.2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETO06859.1 - 0.0005 20.1 0.0 0.00071 19.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 ETO06859.1 - 0.0011 18.6 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain NB-ARC PF00931.17 ETO06859.1 - 0.0012 17.7 0.1 0.0012 17.7 0.1 2.3 1 1 2 3 3 3 1 NB-ARC domain AAA_22 PF13401.1 ETO06859.1 - 0.0031 17.6 0.0 0.008 16.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 ETO06859.1 - 0.0032 16.4 2.4 0.018 14.0 0.0 2.6 1 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 ETO06859.1 - 0.0047 17.0 4.4 0.17 12.0 0.0 3.1 1 1 2 3 3 3 1 RNA helicase Mg_chelatase PF01078.16 ETO06859.1 - 0.013 14.7 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Phe_hydrox_dim PF07976.7 ETO06859.1 - 0.023 14.3 0.5 0.58 9.7 0.3 2.1 1 1 0 1 1 1 0 Phenol hydroxylase, C-terminal dimerisation domain AAA_25 PF13481.1 ETO06859.1 - 0.023 14.0 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 ETO06859.1 - 0.038 13.4 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain DRY_EERY PF09750.4 ETO06859.1 - 0.045 13.8 4.7 0.06 13.4 3.0 1.4 1 1 0 1 1 1 0 Alternative splicing regulator AAA_30 PF13604.1 ETO06859.1 - 0.051 13.1 0.4 0.26 10.8 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.1 ETO06859.1 - 0.063 13.5 1.5 0.46 10.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain Torsin PF06309.6 ETO06859.1 - 0.089 12.6 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Torsin GIY-YIG PF01541.19 ETO06859.1 - 0.78 10.1 6.6 23 5.4 0.0 2.5 2 0 0 2 2 2 0 GIY-YIG catalytic domain SPT16 PF08644.6 ETO06859.1 - 1.2 8.9 4.7 5 6.9 0.1 2.3 1 1 1 2 2 2 0 FACT complex subunit (SPT16/CDC68) HEAT_2 PF13646.1 ETO06860.1 - 1.5e-10 41.1 0.1 0.006 16.8 0.0 5.4 2 1 5 7 7 7 5 HEAT repeats HEAT PF02985.17 ETO06860.1 - 3.7e-07 29.6 9.2 0.64 10.2 0.0 7.8 10 0 0 10 10 10 2 HEAT repeat UME PF08064.8 ETO06860.1 - 0.00012 21.9 11.1 0.00024 21.0 0.1 4.5 4 2 1 5 5 5 1 UME (NUC010) domain HEAT_EZ PF13513.1 ETO06860.1 - 0.00015 22.1 0.0 4.2 7.9 0.0 5.9 7 0 0 7 7 7 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 ETO06860.1 - 0.0028 18.0 15.8 0.54 10.6 0.4 5.6 4 2 0 4 4 4 2 Vacuolar 14 Fab1-binding region CRM1_C PF08767.6 ETO06861.1 - 5.5e-06 25.5 1.0 1.1e-05 24.5 0.3 1.8 1 1 0 2 2 2 1 CRM1 C terminal MOR2-PAG1_N PF14222.1 ETO06861.1 - 0.00037 19.3 0.1 0.058 12.0 0.2 2.1 1 1 1 2 2 2 2 Cell morphogenesis N-terminal Proteasom_PSMB PF10508.4 ETO06861.1 - 0.00085 17.7 1.1 0.0011 17.3 0.7 1.2 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit HEAT_2 PF13646.1 ETO06861.1 - 0.0026 17.9 0.0 0.1 12.9 0.0 2.8 2 1 1 3 3 3 1 HEAT repeats HEAT PF02985.17 ETO06861.1 - 0.0075 16.2 0.1 4 7.7 0.0 3.5 4 0 0 4 4 4 1 HEAT repeat DUF1546 PF07571.8 ETO06861.1 - 0.021 14.9 0.2 3.4 7.8 0.0 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1546) DUF3427 PF11907.3 ETO06861.1 - 0.06 12.2 0.5 0.081 11.8 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3427) UPRTase PF14681.1 ETO06864.1 - 7.4e-13 48.1 0.1 1.7e-11 43.7 0.0 2.2 2 0 0 2 2 2 2 Uracil phosphoribosyltransferase ABC_membrane_2 PF06472.10 ETO06865.1 - 4e-40 137.7 1.6 5.3e-40 137.3 1.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 ETO06865.1 - 4.8e-10 39.8 0.0 1.8e-09 38.0 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 ETO06865.1 - 9.1e-06 25.8 0.0 2.3e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 ETO06865.1 - 0.0035 17.0 0.0 0.0061 16.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_23 PF13476.1 ETO06865.1 - 0.0042 17.4 0.1 0.0042 17.4 0.1 2.5 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.14 ETO06865.1 - 0.013 14.7 0.0 0.027 13.7 0.0 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 ETO06865.1 - 0.034 13.6 0.0 0.08 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.16 ETO06865.1 - 0.037 13.1 0.0 0.088 11.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 ETO06865.1 - 0.085 13.0 0.0 0.4 10.8 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETO06865.1 - 0.088 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 ETO06865.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 ETO06865.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain PGI PF00342.14 ETO06866.1 - 2.5e-135 451.6 0.0 5.3e-107 358.2 0.0 2.0 1 1 1 2 2 2 2 Phosphoglucose isomerase RVT_1 PF00078.22 ETO06867.1 - 1.5e-32 112.6 1.4 2.4e-32 112.0 0.1 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 ETO06867.1 - 7.7e-22 77.1 0.5 2.8e-21 75.3 0.3 2.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.18 ETO06867.1 - 0.23 11.4 12.7 0.95 9.5 1.6 2.7 2 0 0 2 2 2 0 Zinc knuckle Dispanin PF04505.7 ETO06870.1 - 2.5e-11 42.9 1.8 4.8e-11 42.0 1.2 1.4 1 0 0 1 1 1 1 Interferon-induced transmembrane protein Sir1 PF11603.3 ETO06871.1 - 0.094 12.8 1.5 0.16 12.1 0.9 1.6 1 1 0 1 1 1 0 Regulatory protein Sir1 Egg_lysin PF01303.12 ETO06871.1 - 2.7 8.0 7.1 21 5.1 1.0 3.3 2 1 1 3 3 3 0 Egg lysin (Sperm-lysin) Aldo_ket_red PF00248.16 ETO06873.1 - 0.0007 18.5 0.5 0.086 11.6 0.1 2.2 1 1 1 2 2 2 2 Aldo/keto reductase family Tnp_P_element PF12017.3 ETO06874.1 - 0.025 13.8 0.2 0.036 13.2 0.2 1.2 1 0 0 1 1 1 0 Transposase protein EF-hand_like PF09279.6 ETO06874.1 - 0.049 13.6 1.4 1.8 8.6 0.0 3.0 2 1 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like FliT PF05400.8 ETO06874.1 - 0.52 10.7 3.2 0.35 11.3 0.4 2.1 3 0 0 3 3 3 0 Flagellar protein FliT TnpV PF14198.1 ETO06874.1 - 0.63 9.9 9.9 2.1 8.2 2.7 2.4 2 0 0 2 2 2 0 Transposon-encoded protein TnpV ResIII PF04851.10 ETO06874.1 - 1.1 9.0 7.1 0.61 9.8 3.5 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Cir_N PF10197.4 ETO06876.1 - 1.6 8.8 4.8 3.6 7.7 3.3 1.6 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR Miro PF08477.8 ETO06877.1 - 6.8e-08 33.0 0.0 1.5e-07 31.8 0.0 1.6 1 1 0 1 1 1 1 Miro-like protein Ras PF00071.17 ETO06877.1 - 5.8e-07 29.0 0.0 8.3e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Ras family Ribosomal_S7e PF01251.13 ETO06878.1 - 1.5e-54 184.3 6.8 5.8e-46 156.3 2.5 3.2 2 1 0 2 2 2 2 Ribosomal protein S7e DUF2201_N PF13203.1 ETO06878.1 - 1.4 8.0 10.9 2 7.4 7.6 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain GET2 PF08690.5 ETO06879.1 - 0.0016 17.7 2.2 0.0022 17.3 1.5 1.1 1 0 0 1 1 1 1 GET complex subunit GET2 Neur_chan_memb PF02932.11 ETO06879.1 - 0.011 15.6 5.5 0.1 12.4 3.5 2.0 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region VWA_2 PF13519.1 ETO06880.1 - 5.9e-10 39.5 0.0 1.2e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Helicase_C PF00271.26 ETO06880.1 - 0.046 13.5 0.0 0.42 10.5 0.0 2.7 3 0 0 3 3 3 0 Helicase conserved C-terminal domain WD40 PF00400.27 ETO06881.1 - 7.7e-67 218.9 16.1 1e-11 44.2 0.2 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO06881.1 - 3.8e-12 45.1 6.2 0.0012 17.0 0.0 5.9 2 1 1 5 5 5 5 Nucleoporin Nup120/160 Latarcin PF10279.4 ETO06882.1 - 0.0037 17.4 0.0 0.2 11.8 0.0 3.6 1 1 0 1 1 1 1 Latarcin precursor GrpE PF01025.14 ETO06883.1 - 0.048 13.1 2.3 0.43 10.1 0.2 2.1 2 0 0 2 2 2 0 GrpE Peptidase_M55 PF04951.8 ETO06884.1 - 0.016 14.4 0.8 0.87 8.7 0.4 2.1 1 1 1 2 2 2 0 D-aminopeptidase Med9 PF07544.8 ETO06884.1 - 0.021 14.5 2.6 0.064 12.9 1.6 2.1 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Imm22 PF15592.1 ETO06884.1 - 0.068 13.4 3.4 0.9 9.8 0.6 2.5 1 1 1 2 2 2 0 Immunity protein 22 L31 PF09784.4 ETO06884.1 - 0.14 12.2 3.1 0.3 11.1 2.1 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 NAAA-beta PF15508.1 ETO06884.1 - 0.62 10.4 2.8 1 9.7 0.4 2.4 2 1 1 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Wx5_PLAF3D7 PF09688.5 ETO06884.1 - 0.63 10.0 11.8 0.72 9.8 1.6 2.7 1 1 1 3 3 3 0 Protein of unknown function (Wx5_PLAF3D7) ATP-cone PF03477.11 ETO06884.1 - 1.6 9.2 7.1 7.3 7.0 1.9 2.5 1 1 1 2 2 2 0 ATP cone domain Syntaxin_2 PF14523.1 ETO06884.1 - 6.3 6.8 11.5 4.1 7.5 4.6 2.7 2 1 1 3 3 3 0 Syntaxin-like protein WD40 PF00400.27 ETO06885.1 - 7.5e-66 215.8 23.3 1e-11 44.1 0.0 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO06885.1 - 1.7e-14 52.8 6.5 0.0011 17.2 0.1 5.9 1 1 4 6 6 6 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO06885.1 - 8.6e-05 21.4 14.8 0.067 11.9 4.0 3.8 1 1 1 2 2 2 2 Nup133 N terminal like DUF3601 PF12208.3 ETO06885.1 - 0.014 15.3 0.0 3.5 7.6 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3601) Glyphos_transf PF04464.9 ETO06885.1 - 0.026 13.2 0.1 0.054 12.2 0.0 1.4 1 0 0 1 1 1 0 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase DASH_Ask1 PF08655.5 ETO06886.1 - 0.0015 18.3 0.4 0.004 16.9 0.3 1.7 1 0 0 1 1 1 1 DASH complex subunit Ask1 WD40 PF00400.27 ETO06887.1 - 2.9e-21 74.4 13.7 5.6e-10 38.7 0.1 3.9 3 1 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO06887.1 - 7e-05 21.1 0.6 0.08 11.0 0.1 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 RicinB_lectin_2 PF14200.1 ETO06887.1 - 0.12 12.7 0.0 1 9.7 0.0 2.4 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like Toxin_28 PF08115.6 ETO06887.1 - 1.1 9.0 8.6 2.1 8.0 0.6 2.7 2 0 0 2 2 2 0 SFI toxin family LANC_like PF05147.8 ETO06888.1 - 0.064 11.8 0.6 0.073 11.6 0.4 1.1 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein WD40 PF00400.27 ETO06890.1 - 2.5e-75 245.8 17.3 3.7e-13 48.8 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO06890.1 - 8e-14 51.7 0.5 0.00033 20.4 0.0 3.2 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO06890.1 - 6.4e-07 27.9 3.4 0.0004 18.8 0.1 3.4 1 1 3 4 4 4 2 Cytochrome D1 heme domain Nup160 PF11715.3 ETO06890.1 - 1.6e-06 26.5 6.8 0.32 9.0 0.2 4.5 1 1 3 4 4 4 3 Nucleoporin Nup120/160 DUF1258 PF06869.7 ETO06890.1 - 1.9e-05 23.8 1.5 0.15 11.1 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF1258) DUF1652 PF07865.6 ETO06890.1 - 7.2e-05 22.3 0.3 1.2 8.8 0.0 5.1 5 1 2 7 7 7 1 Protein of unknown function (DUF1652) PQQ_2 PF13360.1 ETO06890.1 - 7.2e-05 22.3 0.2 0.21 11.0 0.0 2.9 1 1 1 3 3 3 2 PQQ-like domain DPPIV_N PF00930.16 ETO06890.1 - 9.5e-05 21.1 0.0 0.29 9.6 0.0 3.9 1 1 2 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Proteasome_A_N PF10584.4 ETO06890.1 - 0.00029 20.1 5.0 7.2 6.0 0.0 5.9 6 0 0 6 6 6 1 Proteasome subunit A N-terminal signature NodS PF05401.6 ETO06890.1 - 0.001 18.5 0.5 13 5.0 0.0 3.7 1 1 2 4 4 4 0 Nodulation protein S (NodS) TRA-1_regulated PF02343.11 ETO06890.1 - 0.0088 15.5 0.1 0.46 9.9 0.0 2.9 2 2 1 4 4 4 1 TRA-1 regulated protein R03H10.4 Resistin PF06954.6 ETO06890.1 - 0.012 15.9 3.5 28 5.0 0.0 4.3 2 1 1 4 4 4 0 Resistin SusE PF14292.1 ETO06890.1 - 0.016 15.0 0.1 34 4.2 0.0 3.6 4 0 0 4 4 4 0 SusE outer membrane protein PD40 PF07676.7 ETO06890.1 - 0.023 14.3 7.1 7.6 6.3 0.1 5.3 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat DUF3240 PF11582.3 ETO06890.1 - 0.037 13.9 0.0 39 4.2 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3240) TFIIIC_delta PF12657.2 ETO06890.1 - 7.3 6.2 8.0 3.9 7.1 0.7 2.8 3 1 0 3 3 3 0 Transcription factor IIIC subunit delta N-term Beta_elim_lyase PF01212.16 ETO06892.1 - 9.2e-66 221.9 0.0 1.2e-65 221.5 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Ycf1 PF05758.7 ETO06894.1 - 0.00091 17.0 10.8 0.0012 16.6 7.5 1.2 1 0 0 1 1 1 1 Ycf1 Astro_capsid PF03115.9 ETO06894.1 - 0.0045 15.3 1.5 0.0042 15.4 1.0 1.1 1 0 0 1 1 1 1 Astrovirus capsid protein precursor Adaptin_binding PF10199.4 ETO06894.1 - 0.034 14.4 16.3 0.054 13.7 11.3 1.4 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 BSP_II PF05432.6 ETO06894.1 - 0.04 13.2 20.9 0.056 12.7 14.5 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Zip PF02535.17 ETO06894.1 - 0.22 10.4 1.0 0.28 10.1 0.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Peroxin-13_N PF04088.8 ETO06894.1 - 0.27 11.2 5.0 2.8 7.8 0.8 2.5 2 1 1 3 3 3 0 Peroxin 13, N-terminal region SDA1 PF05285.7 ETO06894.1 - 0.39 9.9 29.1 0.32 10.2 15.1 2.1 2 0 0 2 2 2 0 SDA1 G-7-MTase PF12803.2 ETO06894.1 - 0.45 9.6 4.4 0.67 9.0 3.1 1.2 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) DUF1510 PF07423.6 ETO06894.1 - 0.59 9.4 24.4 1.4 8.2 16.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Daxx PF03344.10 ETO06894.1 - 0.61 8.5 25.4 0.89 7.9 17.6 1.2 1 0 0 1 1 1 0 Daxx Family Ca_hom_mod PF14798.1 ETO06894.1 - 0.8 8.6 0.0 0.8 8.6 0.0 2.0 2 1 0 2 2 2 0 Calcium homeostasis modulator DUF1448 PF07289.6 ETO06894.1 - 1.4 7.7 9.7 0.4 9.5 4.7 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1448) Mem_trans PF03547.13 ETO06894.1 - 2.1 6.5 4.5 3.1 5.9 3.1 1.2 1 0 0 1 1 1 0 Membrane transport protein Neur_chan_memb PF02932.11 ETO06894.1 - 4.1 7.2 5.8 4.7 7.0 3.4 1.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region FHIPEP PF00771.15 ETO06894.1 - 9 4.4 6.5 13 4.0 4.5 1.2 1 0 0 1 1 1 0 FHIPEP family VHS PF00790.14 ETO06896.1 - 0.032 13.8 1.1 0.14 11.7 0.0 2.1 2 1 1 3 3 3 0 VHS domain PCI_Csn8 PF10075.4 ETO06896.1 - 0.06 13.1 0.6 0.1 12.3 0.4 1.6 1 1 0 1 1 1 0 COP9 signalosome, subunit CSN8 DUF2361 PF10153.4 ETO06896.1 - 0.11 12.6 1.3 0.23 11.6 0.7 1.7 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) BSMAP PF12280.3 ETO06896.1 - 0.28 11.0 4.4 0.62 9.9 3.1 1.7 1 1 0 1 1 1 0 Brain specific membrane anchored protein DUF3069 PF11269.3 ETO06896.1 - 0.3 11.1 3.0 0.32 11.0 0.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3069) YgaB PF14182.1 ETO06896.1 - 5 7.4 7.2 77 3.6 2.4 3.1 2 1 0 2 2 2 0 YgaB-like protein GAGA_bind PF06217.7 ETO06897.1 - 2.4 8.0 30.6 3.1 7.6 21.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Stap_Strp_tox_C PF02876.12 ETO06900.1 - 0.11 12.6 7.0 0.21 11.7 0.9 2.5 1 1 0 2 2 2 0 Staphylococcal/Streptococcal toxin, beta-grasp domain PUF PF00806.14 ETO06901.1 - 4.6e-07 28.9 0.1 0.047 13.1 0.0 3.1 3 0 0 3 3 3 2 Pumilio-family RNA binding repeat IncA PF04156.9 ETO06902.1 - 0.0057 16.2 14.6 0.014 15.0 10.1 1.6 1 1 0 1 1 1 1 IncA protein DivIC PF04977.10 ETO06902.1 - 0.013 15.0 15.9 0.078 12.4 0.8 3.3 2 1 2 4 4 4 0 Septum formation initiator Brevenin PF03032.10 ETO06902.1 - 0.016 15.0 0.5 0.087 12.6 0.4 2.3 1 1 0 1 1 1 0 Brevenin/esculentin/gaegurin/rugosin family Kinesin-relat_1 PF12711.2 ETO06902.1 - 0.08 13.3 8.5 0.36 11.2 0.4 2.5 2 0 0 2 2 2 0 Kinesin motor Cep57_CLD_2 PF14197.1 ETO06902.1 - 0.088 12.7 8.0 2 8.4 0.5 2.8 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 K-box PF01486.12 ETO06902.1 - 0.096 12.4 0.2 0.096 12.4 0.1 3.5 3 1 1 4 4 4 0 K-box region Cnd1_N PF12922.2 ETO06902.1 - 0.11 12.1 5.3 0.044 13.4 1.4 1.9 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term UPF0242 PF06785.6 ETO06902.1 - 0.11 11.0 8.7 0.034 12.8 0.7 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) FlaC_arch PF05377.6 ETO06902.1 - 0.17 11.8 4.6 8.4 6.3 0.1 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Strep_SA_rep PF06696.6 ETO06902.1 - 0.18 11.5 8.0 0.33 10.7 0.9 2.5 2 0 0 2 2 2 0 Streptococcal surface antigen repeat KfrA_N PF11740.3 ETO06902.1 - 0.24 11.8 5.2 2.6 8.5 0.1 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Phage_lysis PF03245.8 ETO06902.1 - 0.44 10.5 6.9 4.7 7.2 0.6 2.4 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein TSC22 PF01166.13 ETO06902.1 - 0.57 10.1 4.6 1.7 8.6 0.3 2.6 2 1 0 2 2 2 0 TSC-22/dip/bun family bZIP_1 PF00170.16 ETO06902.1 - 5 7.1 18.0 0.11 12.4 0.8 3.1 3 1 0 3 3 3 0 bZIP transcription factor Viral_P18 PF04521.8 ETO06902.1 - 6.2 6.2 8.6 1.8 8.0 0.3 2.7 1 1 2 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein Mak10 PF04112.8 ETO06905.1 - 7.2e-05 22.0 0.2 0.016 14.4 0.0 3.0 2 1 1 3 3 3 2 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase ERF PF04404.7 ETO06905.1 - 0.059 12.9 0.1 0.099 12.1 0.1 1.3 1 0 0 1 1 1 0 ERF superfamily Pkinase PF00069.20 ETO06906.1 - 2e-16 59.9 0.1 5.4e-15 55.2 0.1 2.5 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO06906.1 - 1.3e-06 27.6 0.0 2.1e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO06906.1 - 7.7e-05 21.8 0.1 0.00014 20.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 ETO06906.1 - 0.027 14.0 1.4 0.037 13.6 0.5 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase Metallophos PF00149.23 ETO06909.1 - 6.3e-36 123.6 0.2 8.2e-36 123.2 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 ETO06909.1 - 0.0049 16.7 0.0 0.0099 15.7 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain WD40 PF00400.27 ETO06911.1 - 7.9e-31 104.8 12.5 4e-11 42.3 0.0 3.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO06911.1 - 9.1e-07 27.3 0.7 0.15 10.1 0.0 3.0 1 1 1 3 3 3 3 Nucleoporin Nup120/160 DUF1900 PF08954.6 ETO06911.1 - 0.004 16.6 0.1 4.2 6.8 0.0 2.8 1 1 1 3 3 3 2 Domain of unknown function (DUF1900) DUF3601 PF12208.3 ETO06911.1 - 0.012 15.4 0.1 0.13 12.2 0.0 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF3601) DUF4221 PF13970.1 ETO06911.1 - 0.14 11.4 3.2 0.52 9.5 0.2 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4221) Transglut_core PF01841.14 ETO06912.1 - 2.4e-11 43.8 0.0 5.7e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF1510 PF07423.6 ETO06913.1 - 0.0044 16.4 12.2 0.015 14.6 8.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) DUF2721 PF11026.3 ETO06913.1 - 0.0071 15.9 0.1 0.0071 15.9 0.1 3.2 3 1 1 4 4 4 1 Protein of unknown function (DUF2721) CDC45 PF02724.9 ETO06913.1 - 0.88 7.5 11.0 1.4 6.9 7.6 1.2 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.27 ETO06914.1 - 1.1e-23 82.2 12.6 1.2e-08 34.4 0.6 4.2 3 1 1 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO06914.1 - 2e-05 22.9 0.0 0.00028 19.1 0.1 2.0 1 1 0 2 2 2 1 Nucleoporin Nup120/160 DUF1900 PF08954.6 ETO06914.1 - 0.075 12.5 0.0 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1900) Kelch_6 PF13964.1 ETO06914.1 - 0.12 12.6 0.5 13 6.1 0.1 2.7 2 0 0 2 2 2 0 Kelch motif Pkinase_Tyr PF07714.12 ETO06916.1 - 1.2e-67 227.7 0.0 1.5e-67 227.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 ETO06916.1 - 2.5e-53 180.8 0.0 3.5e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 ETO06916.1 - 0.0013 17.7 0.1 0.0021 17.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 ETO06916.1 - 0.015 14.5 0.0 0.046 13.0 0.0 1.7 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Kinase-like PF14531.1 ETO06916.1 - 0.099 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Penicillinase_R PF03965.11 ETO06917.1 - 0.13 12.3 2.2 0.34 11.0 1.5 1.7 1 0 0 1 1 1 0 Penicillinase repressor Spore_III_AF PF09581.5 ETO06917.1 - 0.32 10.8 6.7 0.5 10.1 4.6 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) FlgN PF05130.7 ETO06918.1 - 0.054 13.7 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 FlgN protein CLASP_N PF12348.3 ETO06919.1 - 4.1e-05 23.0 0.1 0.003 16.9 0.0 2.2 2 0 0 2 2 2 2 CLASP N terminal CBF PF03914.12 ETO06919.1 - 0.0015 18.0 0.5 0.0034 16.8 0.2 1.6 1 1 0 1 1 1 1 CBF/Mak21 family WD40 PF00400.27 ETO06920.1 - 3e-13 49.0 3.5 3.3e-07 29.9 0.2 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat FBPase_glpX PF03320.8 ETO06920.1 - 0.0039 15.8 0.0 0.0064 15.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded Ank_4 PF13637.1 ETO06921.1 - 2.3e-15 56.6 0.2 1.3e-10 41.4 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO06921.1 - 8.2e-15 54.9 0.4 3.1e-14 53.0 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO06921.1 - 3.3e-14 51.8 0.2 1.3e-06 27.9 0.0 4.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 ETO06921.1 - 3.3e-13 48.4 0.7 1.2e-07 31.2 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 ETO06921.1 - 6.6e-09 35.7 0.8 4.7e-07 29.8 0.1 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) DUF2320 PF10082.4 ETO06921.1 - 0.079 11.6 1.5 0.11 11.2 1.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2320) Neisseria_TspB PF05616.8 ETO06921.1 - 1 7.6 10.2 1.5 7.0 7.0 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Granin PF01271.12 ETO06925.1 - 0.053 12.2 13.1 0.063 11.9 9.1 1.0 1 0 0 1 1 1 0 Granin (chromogranin or secretogranin) DUF1822 PF08852.6 ETO06925.1 - 0.12 11.2 1.5 0.15 10.8 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) SR-25 PF10500.4 ETO06925.1 - 0.53 9.7 11.4 0.62 9.5 7.9 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TMEM247 PF15444.1 ETO06926.1 - 0.048 13.4 1.6 0.062 13.1 1.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 247 DUF16 PF01519.11 ETO06926.1 - 0.089 13.0 5.8 0.07 13.3 2.6 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF2981 PF11200.3 ETO06926.1 - 2.6 7.0 9.3 1.1 8.2 4.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) Ank_2 PF12796.2 ETO06928.1 - 1.4e-45 153.5 1.2 1.2e-20 73.6 0.0 2.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO06928.1 - 3.4e-26 91.1 0.2 9.4e-11 41.9 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 ETO06928.1 - 1.1e-24 84.9 0.2 1.1e-09 37.5 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 ETO06928.1 - 7.6e-19 65.9 0.0 4.2e-06 26.4 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 ETO06928.1 - 1.4e-16 60.1 0.4 9.9e-08 31.9 0.0 4.2 1 1 3 4 4 4 3 Ankyrin repeats (many copies) CM_2 PF01817.16 ETO06929.1 - 0.012 15.6 0.4 0.96 9.5 0.1 2.0 1 1 1 2 2 2 0 Chorismate mutase type II MTD PF01993.13 ETO06929.1 - 0.062 12.3 0.1 0.067 12.2 0.1 1.0 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase Pyrophosphatase PF00719.14 ETO06929.1 - 0.078 12.4 2.1 0.08 12.3 1.4 1.1 1 0 0 1 1 1 0 Inorganic pyrophosphatase CaM_binding PF07839.6 ETO06929.1 - 0.11 12.7 1.2 0.12 12.5 0.8 1.1 1 0 0 1 1 1 0 Plant calmodulin-binding domain Peptidase_U35_2 PF14550.1 ETO06929.1 - 0.19 11.3 1.9 0.32 10.6 0.4 1.8 1 1 1 2 2 2 0 Putative phage protease XkdF PrgU PF09627.5 ETO06929.1 - 0.26 10.8 3.8 0.28 10.7 2.4 1.4 1 1 0 1 1 1 0 PrgU-like protein TcdB_N PF12918.2 ETO06929.1 - 1.3 9.1 6.2 2 8.5 4.3 1.2 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain Hist_deacetyl PF00850.14 ETO06932.1 - 8e-69 232.2 0.6 2.3e-68 230.7 0.2 1.7 2 0 0 2 2 2 1 Histone deacetylase domain Hyphal_reg_CWP PF11765.3 ETO06932.1 - 0.098 11.4 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Hyphally regulated cell wall protein N-terminal TRI9 PF08195.6 ETO06932.1 - 0.11 12.0 0.0 2 8.1 0.0 2.3 2 0 0 2 2 2 0 TRI9 protein DUF912 PF06024.7 ETO06933.1 - 0.063 13.3 5.7 0.57 10.2 2.0 2.8 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Menin PF05053.8 ETO06933.1 - 0.07 11.3 4.2 0.088 10.9 2.9 1.1 1 0 0 1 1 1 0 Menin cNMP_binding PF00027.24 ETO06935.1 - 3e-14 52.6 0.1 5.7e-06 26.0 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase PF00069.20 ETO06936.1 - 0.0005 19.2 0.1 0.0011 18.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain DUF2540 PF10802.3 ETO06936.1 - 0.13 11.9 0.4 0.46 10.2 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2540) DUF4339 PF14237.1 ETO06938.1 - 5.3e-05 22.6 0.0 0.00011 21.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4339) GYF PF02213.11 ETO06938.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 GYF domain NUDIX PF00293.23 ETO06939.1 - 2.4e-14 53.1 0.0 7.4e-12 45.0 0.0 2.4 2 0 0 2 2 2 2 NUDIX domain Aminotran_1_2 PF00155.16 ETO06940.1 - 2.1e-09 36.8 0.0 3.2e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_1_2 PF00155.16 ETO06941.1 - 4.3e-09 35.7 0.0 5e-09 35.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II PFK PF00365.15 ETO06942.1 - 2.7e-22 79.0 0.0 3.5e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Phosphofructokinase Ribosomal_S5 PF00333.15 ETO06942.1 - 0.14 11.8 0.1 0.64 9.8 0.0 2.1 2 1 0 2 2 2 0 Ribosomal protein S5, N-terminal domain Nucleoside_tran PF01733.13 ETO06943.1 - 0.011 14.8 0.4 0.017 14.3 0.3 1.2 1 0 0 1 1 1 0 Nucleoside transporter Phage_holin_T PF11031.3 ETO06943.1 - 0.019 14.1 1.5 0.033 13.3 1.1 1.3 1 0 0 1 1 1 0 Bacteriophage T holin DUF1510 PF07423.6 ETO06943.1 - 0.019 14.3 3.7 0.028 13.7 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pox_LP_H2 PF03356.10 ETO06943.1 - 0.023 14.3 0.4 0.039 13.6 0.3 1.3 1 0 0 1 1 1 0 Viral late protein H2 Peptidase_S49_N PF08496.5 ETO06943.1 - 0.04 13.7 1.8 0.087 12.6 1.2 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Shisa PF13908.1 ETO06943.1 - 0.041 14.0 0.6 0.069 13.3 0.4 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator SID-1_RNA_chan PF13965.1 ETO06943.1 - 0.06 11.5 3.0 0.084 11.0 2.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Sarcoglycan_1 PF04790.8 ETO06943.1 - 0.07 12.2 3.9 0.11 11.6 2.7 1.2 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein ODV-E18 PF10717.4 ETO06943.1 - 0.24 10.8 8.3 0.029 13.7 2.5 2.0 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 DUF843 PF05814.6 ETO06943.1 - 0.36 10.6 7.7 0.085 12.6 2.8 1.9 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) Ly49 PF08391.5 ETO06943.1 - 0.82 9.8 4.2 2.3 8.3 2.8 1.8 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region RabGAP-TBC PF00566.13 ETO06944.1 - 1.2e-24 86.9 0.4 1.2e-24 86.9 0.3 2.0 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Chordopox_A30L PF06015.7 ETO06944.1 - 0.094 12.3 0.1 1.6 8.4 0.0 2.8 2 0 0 2 2 2 0 Chordopoxvirus A30L protein Ribosomal_S8e PF01201.17 ETO06945.1 - 0.19 11.8 4.3 0.32 11.1 0.6 2.2 2 0 0 2 2 2 0 Ribosomal protein S8e BLVR PF06375.6 ETO06945.1 - 0.77 9.5 12.8 0.08 12.7 0.6 2.9 3 0 0 3 3 3 0 Bovine leukaemia virus receptor (BLVR) Cnd1_N PF12922.2 ETO06945.1 - 3.6 7.1 6.4 9 5.8 1.4 2.4 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term Ribosomal_60s PF00428.14 ETO06946.1 - 0.063 13.6 0.3 0.063 13.6 0.2 5.5 4 1 0 4 4 4 0 60s Acidic ribosomal protein DUF1758 PF05585.7 ETO06947.1 - 0.11 12.0 0.1 0.11 12.0 0.1 1.5 2 0 0 2 2 2 0 Putative peptidase (DUF1758) DJ-1_PfpI PF01965.19 ETO06949.1 - 6.9e-22 77.4 0.4 5.6e-20 71.3 0.0 2.5 1 1 1 2 2 2 2 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 ETO06949.1 - 2.8e-17 61.9 0.1 5.6e-17 60.9 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family Pho86 PF11124.3 ETO06950.1 - 0.00045 19.3 1.1 0.0011 18.0 0.7 1.6 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 RGS PF00615.14 ETO06951.1 - 5.2e-05 23.3 0.0 6.3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain LBP_BPI_CETP PF01273.20 ETO06951.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 LBP / BPI / CETP family, N-terminal domain WEMBL PF05701.6 ETO06952.1 - 0.001 17.6 12.9 0.001 17.6 8.9 3.8 3 1 0 3 3 3 1 Weak chloroplast movement under blue light MtrG PF04210.8 ETO06952.1 - 0.029 14.0 1.9 0.18 11.4 0.1 3.0 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Reo_sigmaC PF04582.7 ETO06952.1 - 0.14 11.3 11.5 0.6 9.2 1.0 2.5 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Fungal_trans_2 PF11951.3 ETO06952.1 - 0.27 9.8 8.3 0.1 11.1 3.4 1.9 1 1 1 2 2 2 0 Fungal specific transcription factor domain PspA_IM30 PF04012.7 ETO06952.1 - 5.8 6.2 43.7 0.67 9.2 0.6 6.1 3 2 1 4 4 4 0 PspA/IM30 family TLD PF07534.11 ETO06953.1 - 1.1e-12 48.1 1.8 2.2e-12 47.1 0.6 1.9 1 1 1 2 2 2 1 TLD BBS2_Mid PF14783.1 ETO06953.1 - 0.086 12.6 0.1 0.42 10.4 0.1 2.2 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region PSI_PsaF PF02507.10 ETO06954.1 - 0.045 13.3 0.6 0.1 12.1 0.0 1.9 2 1 1 3 3 3 0 Photosystem I reaction centre subunit III OST-HTH PF12872.2 ETO06957.1 - 3.4e-05 23.6 0.2 0.0033 17.2 0.1 3.5 3 0 0 3 3 3 1 OST-HTH/LOTUS domain ERF PF04404.7 ETO06957.1 - 0.007 15.9 1.4 0.02 14.4 0.9 1.8 1 0 0 1 1 1 1 ERF superfamily DDHD PF02862.12 ETO06957.1 - 0.46 10.2 12.3 0.48 10.1 3.3 2.3 2 0 0 2 2 2 0 DDHD domain WD40 PF00400.27 ETO06960.1 - 3e-31 106.1 7.9 1.5e-12 46.8 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO06960.1 - 2e-09 36.1 0.0 1.5e-05 23.3 0.1 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO06960.1 - 0.0079 14.9 1.8 6 5.4 0.1 3.0 2 1 1 3 3 3 2 Nup133 N terminal like DUF4221 PF13970.1 ETO06960.1 - 0.043 13.1 0.3 0.11 11.7 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4221) Marek_SORF3 PF07153.6 ETO06960.1 - 0.099 11.2 0.1 0.14 10.7 0.1 1.2 1 0 0 1 1 1 0 Marek's disease-like virus SORF3 protein PHD PF00628.24 ETO06962.1 - 4.5e-05 23.0 4.7 4.5e-05 23.0 3.3 2.3 3 0 0 3 3 3 1 PHD-finger XH PF03469.9 ETO06962.1 - 0.019 14.6 1.0 0.052 13.2 0.7 1.8 1 0 0 1 1 1 0 XH domain Sec62 PF03839.11 ETO06963.1 - 8.4 5.7 9.2 17 4.7 6.4 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 UCH PF00443.24 ETO06964.1 - 1.7e-47 161.8 9.9 1.7e-47 161.8 6.9 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO06964.1 - 4.8e-15 55.7 14.7 4.8e-15 55.7 10.2 3.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Lipase_3 PF01764.20 ETO06965.1 - 2e-16 59.8 0.0 3e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Lipase_3 PF01764.20 ETO06966.1 - 9e-05 22.1 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) SRP72 PF08492.7 ETO06966.1 - 0.064 13.6 5.0 1.1 9.6 1.3 2.2 2 0 0 2 2 2 0 SRP72 RNA-binding domain LmjF365940-deam PF14421.1 ETO06967.1 - 0.0025 17.2 0.0 0.0036 16.7 0.0 1.3 1 0 0 1 1 1 1 A distinct subfamily of CDD/CDA-like deaminases dCMP_cyt_deam_1 PF00383.17 ETO06967.1 - 0.027 14.0 0.2 0.25 11.0 0.4 2.0 2 0 0 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region PAP_assoc PF03828.14 ETO06968.1 - 3.3e-05 23.7 0.0 6.1e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase DUF466 PF04328.8 ETO06968.1 - 0.15 11.9 0.1 0.27 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF466) PAP_central PF04928.12 ETO06969.1 - 0.022 13.5 0.1 0.029 13.1 0.1 1.3 1 0 0 1 1 1 0 Poly(A) polymerase central domain PP2C PF00481.16 ETO06970.1 - 1.9e-39 135.6 0.0 2.3e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 ETO06970.1 - 0.0028 17.0 0.0 0.0063 15.9 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C PCMT PF01135.14 ETO06971.1 - 2.5e-17 63.1 0.0 3e-17 62.8 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 ETO06971.1 - 2.3e-05 24.9 0.0 3e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO06971.1 - 3.6e-05 23.3 0.0 4.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 ETO06971.1 - 0.00056 19.6 0.0 0.0011 18.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 ETO06971.1 - 0.0048 16.9 0.0 0.0058 16.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_11 PF08241.7 ETO06971.1 - 0.021 15.2 0.0 0.035 14.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.12 ETO06971.1 - 0.049 12.6 0.0 0.058 12.4 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_24 PF13578.1 ETO06971.1 - 0.059 14.2 0.0 0.083 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 ETO06971.1 - 0.071 13.5 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 ETO06972.1 - 1.7e-06 27.7 0.0 2.4e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pex24p PF06398.6 ETO06972.1 - 0.048 12.4 0.0 0.054 12.2 0.0 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Herpes_env PF01673.13 ETO06973.1 - 6.3 5.2 11.9 9.2 4.6 8.2 1.2 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Mid2 PF04478.7 ETO06974.1 - 0.0022 17.3 2.1 0.0036 16.7 1.5 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor TMEM154 PF15102.1 ETO06974.1 - 0.022 14.4 1.4 0.037 13.7 1.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF916 PF06030.7 ETO06974.1 - 0.23 11.2 2.7 4.4 7.1 0.7 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF916) cNMP_binding PF00027.24 ETO06975.1 - 3.3e-14 52.4 0.0 7.7e-14 51.2 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Erf4 PF10256.4 ETO06975.1 - 0.0054 16.5 0.1 0.013 15.3 0.1 1.6 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF1599 PF07659.6 ETO06975.1 - 0.041 13.9 0.1 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1599) DUF3558 PF12079.3 ETO06975.1 - 0.1 12.2 0.9 0.17 11.5 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) DUF3774 PF12609.3 ETO06975.1 - 0.13 13.1 2.3 0.4 11.5 1.3 1.9 2 0 0 2 2 2 0 Wound-induced protein AATF-Che1 PF13339.1 ETO06975.1 - 0.21 11.7 7.5 3.9 7.6 0.1 3.1 3 0 0 3 3 3 0 Apoptosis antagonizing transcription factor Drf_GBD PF06371.8 ETO06976.1 - 4.3e-14 52.2 1.9 9e-14 51.2 1.3 1.4 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain RTTN_N PF14726.1 ETO06976.1 - 0.0053 17.2 1.5 0.11 13.0 0.3 2.7 2 1 1 3 3 3 1 Rotatin, an armadillo repeat protein, centriole functioning ETRAMP PF09716.5 ETO06976.1 - 0.19 11.7 1.4 0.75 9.7 1.0 2.2 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) EGF_2 PF07974.8 ETO06977.1 - 0.0097 16.0 2.6 0.02 15.0 1.8 1.4 1 0 0 1 1 1 1 EGF-like domain Menin PF05053.8 ETO06978.1 - 0.01 14.0 2.4 0.0097 14.1 1.6 1.1 1 0 0 1 1 1 0 Menin Arrestin_C PF02752.17 ETO06978.1 - 0.087 12.9 3.1 0.13 12.3 2.1 1.4 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain Ctr PF04145.10 ETO06978.1 - 0.25 11.3 2.5 0.35 10.9 1.7 1.5 1 1 0 1 1 1 0 Ctr copper transporter family Med21 PF11221.3 ETO06978.1 - 2.6 8.0 5.4 4.2 7.3 3.7 1.3 1 0 0 1 1 1 0 Subunit 21 of Mediator complex CAP_GLY PF01302.20 ETO06979.1 - 2.4e-09 36.7 1.5 0.0015 18.2 0.1 2.4 2 0 0 2 2 2 2 CAP-Gly domain Hexose_dehydrat PF03559.9 ETO06980.1 - 0.12 11.3 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 NDP-hexose 2,3-dehydratase DUSP PF06337.7 ETO06981.1 - 1.4e-10 41.4 1.4 2.6e-10 40.5 0.0 1.9 2 0 0 2 2 2 1 DUSP domain Secretin_N_2 PF07655.8 ETO06982.1 - 0.13 12.6 9.8 0.2 12.0 6.8 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain DUF912 PF06024.7 ETO06982.1 - 5.1 7.2 9.2 9.1 6.3 6.4 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ASL_C PF08328.6 ETO06983.1 - 0.063 13.1 1.1 1.3 8.9 0.0 3.0 3 0 0 3 3 3 0 Adenylosuccinate lyase C-terminal Arf PF00025.16 ETO06984.1 - 2.5e-07 30.1 0.3 3e-07 29.8 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETO06984.1 - 0.099 11.7 0.1 0.099 11.7 0.1 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region DS PF01916.12 ETO06985.1 - 1.3e-30 106.5 0.1 1.9e-30 106.0 0.1 1.2 1 0 0 1 1 1 1 Deoxyhypusine synthase Remorin_C PF03763.8 ETO06985.1 - 0.03 13.8 6.2 0.056 12.9 4.3 1.3 1 0 0 1 1 1 0 Remorin, C-terminal region DoxA PF07680.6 ETO06985.1 - 0.037 13.6 0.0 0.099 12.2 0.0 1.8 1 1 0 1 1 1 0 TQO small subunit DoxA Coiled PF05710.7 ETO06985.1 - 0.11 12.9 1.4 0.7 10.4 0.2 2.3 2 0 0 2 2 2 0 Coiled coil DS PF01916.12 ETO06986.1 - 9e-66 222.0 0.0 1e-65 221.8 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase RAB3GAP2_N PF14655.1 ETO06989.1 - 7.2e-27 94.4 0.1 2.9e-18 66.0 0.0 2.3 2 0 0 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF2262 PF10020.4 ETO06990.1 - 0.029 14.5 0.1 0.037 14.2 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2262) EpsG PF14897.1 ETO06992.1 - 0.0029 16.6 4.5 0.0031 16.5 3.1 1.2 1 0 0 1 1 1 1 EpsG family DUF1129 PF06570.6 ETO06992.1 - 0.0095 15.2 0.1 0.011 15.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) DUF4293 PF14126.1 ETO06992.1 - 0.02 14.8 0.2 0.022 14.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) Acyl_transf_3 PF01757.17 ETO06992.1 - 0.031 13.1 0.2 0.035 12.9 0.2 1.1 1 0 0 1 1 1 0 Acyltransferase family WD40 PF00400.27 ETO06994.1 - 1.4e-83 272.0 11.8 2.8e-14 52.3 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO06994.1 - 2.2e-12 47.1 0.1 2.3e-08 33.9 0.0 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO06994.1 - 5.5e-08 31.5 1.5 0.00068 18.0 0.0 3.3 1 1 3 4 4 4 3 Cytochrome D1 heme domain Nup160 PF11715.3 ETO06994.1 - 7e-06 24.4 0.8 0.14 10.2 0.1 4.6 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 ETO06994.1 - 1.4e-05 24.1 1.3 0.00061 18.6 0.2 2.3 1 1 0 2 2 2 1 Coatomer WD associated region PQQ_2 PF13360.1 ETO06994.1 - 3.1e-05 23.5 0.0 0.0023 17.4 0.0 2.5 1 1 1 2 2 2 2 PQQ-like domain Nbas_N PF15492.1 ETO06994.1 - 0.00023 20.3 1.5 0.43 9.6 0.0 3.9 2 2 3 5 5 5 1 Neuroblastoma-amplified sequence, N terminal DUF1258 PF06869.7 ETO06994.1 - 0.00056 19.0 0.4 0.032 13.3 0.0 3.0 2 2 1 3 3 3 1 Protein of unknown function (DUF1258) PD40 PF07676.7 ETO06994.1 - 0.00057 19.4 8.2 4.7 6.9 0.0 5.2 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Hira PF07569.6 ETO06994.1 - 0.0062 15.7 0.5 4.3 6.4 0.0 3.8 2 2 2 4 4 4 1 TUP1-like enhancer of split DPPIV_N PF00930.16 ETO06994.1 - 0.017 13.6 0.0 12 4.3 0.0 3.8 1 1 3 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region TPR_12 PF13424.1 ETO06995.1 - 8.6e-26 89.6 7.4 2.3e-13 49.9 1.3 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO06995.1 - 2.6e-14 52.5 9.3 4.6e-08 32.6 0.7 2.3 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETO06995.1 - 6.8e-11 41.2 5.8 0.00066 19.1 1.4 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO06995.1 - 1.2e-10 40.4 0.3 0.03 14.1 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO06995.1 - 1.8e-10 39.9 3.3 0.009 15.8 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO06995.1 - 2.4e-10 39.9 0.0 0.015 15.2 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO06995.1 - 1.1e-08 34.2 4.9 0.0077 15.9 1.4 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat SNAP PF14938.1 ETO06995.1 - 5.5e-07 29.0 0.4 8.5e-07 28.3 0.3 1.3 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.1 ETO06995.1 - 0.0059 16.9 0.0 2.8 8.6 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat APG17 PF04108.7 ETO06995.1 - 0.12 11.1 2.7 0.16 10.7 1.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 Apc3 PF12895.2 ETO06995.1 - 0.6 10.2 6.7 2.4 8.3 3.9 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 NSF PF02071.15 ETO06995.1 - 0.79 10.5 2.9 13 6.8 0.1 3.7 4 0 0 4 4 3 0 Aromatic-di-Alanine (AdAR) repeat AAA PF00004.24 ETO06996.1 - 1.5e-06 28.3 0.1 1.4e-05 25.2 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETO06996.1 - 0.0004 20.1 0.0 0.0017 18.1 0.0 2.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETO06996.1 - 0.00061 19.9 0.0 0.0069 16.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETO06996.1 - 0.0019 18.2 0.1 0.24 11.3 0.0 3.3 3 1 0 3 3 3 1 AAA ATPase domain DUF258 PF03193.11 ETO06996.1 - 0.0024 17.1 0.0 0.008 15.3 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MCM PF00493.18 ETO06996.1 - 0.0068 15.2 0.2 0.11 11.2 0.0 2.4 2 0 0 2 2 2 1 MCM2/3/5 family ABC_tran PF00005.22 ETO06996.1 - 0.0069 16.6 2.8 0.0084 16.4 0.0 2.6 3 0 0 3 3 3 1 ABC transporter PduV-EutP PF10662.4 ETO06996.1 - 0.012 15.1 0.1 0.056 12.9 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 ETO06996.1 - 0.14 12.9 1.4 0.55 11.0 0.1 2.9 2 1 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 ETO06996.1 - 0.18 11.8 2.9 0.85 9.6 0.0 3.4 4 0 0 4 4 4 0 Sigma-54 interaction domain MRP-L47 PF06984.8 ETO06997.1 - 0.087 12.7 0.3 0.24 11.3 0.2 1.7 1 0 0 1 1 1 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) RRF_GI PF12614.3 ETO06999.1 - 0.01 15.6 1.8 0.03 14.1 1.2 1.8 1 0 0 1 1 1 0 Ribosome recycling factor UPF0118 PF01594.11 ETO06999.1 - 0.52 9.2 1.9 2.7 6.8 1.3 1.9 1 1 0 1 1 1 0 Domain of unknown function DUF20 TPR_6 PF13174.1 ETO07000.1 - 0.00085 19.6 0.1 0.0027 18.0 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat MIP-T3 PF10243.4 ETO07001.1 - 1.4e-07 30.4 27.5 1.4e-07 30.4 19.1 2.7 3 0 0 3 3 3 2 Microtubule-binding protein MIP-T3 RNA_polI_A34 PF08208.6 ETO07001.1 - 0.002 17.8 22.6 0.002 17.8 15.7 4.0 2 1 1 3 3 3 1 DNA-directed RNA polymerase I subunit RPA34.5 Alpha_GJ PF03229.8 ETO07001.1 - 8.1 6.8 13.2 19 5.6 9.2 1.5 1 0 0 1 1 1 0 Alphavirus glycoprotein J NfeD PF01957.13 ETO07002.1 - 0.035 14.2 1.7 0.035 14.2 1.2 1.8 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding Thioredoxin_8 PF13905.1 ETO07003.1 - 0.98 9.5 4.7 1.3 9.1 3.2 1.3 1 1 0 1 1 1 0 Thioredoxin-like DUF3338 PF11819.3 ETO07004.1 - 0.41 10.1 0.1 0.41 10.1 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3338) SSP160 PF06933.6 ETO07004.1 - 2 6.2 8.0 3 5.7 5.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 ETO07004.1 - 6 6.6 9.0 14 5.4 6.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TRM13 PF05206.9 ETO07005.1 - 0.023 13.9 1.0 0.037 13.2 0.4 1.4 2 0 0 2 2 2 0 Methyltransferase TRM13 Paramyxo_C PF01692.13 ETO07005.1 - 0.86 9.1 4.2 1.6 8.2 2.9 1.4 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c HI0933_like PF03486.9 ETO07009.1 - 0.0031 16.0 0.1 0.013 13.9 0.1 1.8 1 1 1 2 2 2 1 HI0933-like protein Pox_A_type_inc PF04508.7 ETO07009.1 - 0.81 9.6 0.1 0.81 9.6 0.1 3.4 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Ras PF00071.17 ETO07010.1 - 2.6e-49 166.6 0.2 3.1e-49 166.4 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO07010.1 - 5.1e-11 43.0 0.0 8.4e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO07010.1 - 1.6e-08 33.9 0.0 1.8e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO07010.1 - 4.2e-05 23.0 0.0 5.3e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 ETO07010.1 - 0.036 13.1 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region CENP-B_N PF04218.8 ETO07010.1 - 0.077 12.4 0.1 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain EMP70 PF02990.11 ETO07011.1 - 8.7e-46 156.4 23.4 1.3e-45 155.9 16.2 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 PMP1_2 PF08114.6 ETO07011.1 - 0.031 13.7 0.7 0.07 12.6 0.5 1.5 1 0 0 1 1 1 0 ATPase proteolipid family EMP70 PF02990.11 ETO07012.1 - 6.7e-44 150.2 6.9 7.6e-44 150.0 4.8 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 Chs3p PF12271.3 ETO07012.1 - 0.14 11.1 7.3 0.2 10.6 5.0 1.2 1 0 0 1 1 1 0 Chitin synthase III catalytic subunit DUF3353 PF11833.3 ETO07012.1 - 0.36 10.2 3.8 0.25 10.8 0.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3353) gpUL132 PF11359.3 ETO07012.1 - 0.72 9.1 3.8 0.79 9.0 1.7 1.8 2 0 0 2 2 2 0 Glycoprotein UL132 DUF1129 PF06570.6 ETO07012.1 - 0.95 8.7 10.0 1.2 8.4 6.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) DNA_ligase_A_M PF01068.16 ETO07016.1 - 0.051 12.9 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 ATP dependent DNA ligase domain DHC_N2 PF08393.8 ETO07017.1 - 6.7e-105 350.9 12.1 6.7e-105 350.9 8.4 1.6 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 ETO07017.1 - 9.2e-39 133.3 0.0 1.8e-38 132.4 0.0 1.4 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA PF00004.24 ETO07017.1 - 0.011 15.9 0.2 0.18 12.0 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETO07017.1 - 0.031 14.4 0.3 0.88 9.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 ETO07017.1 - 0.084 13.7 0.3 3.8 8.3 0.0 3.4 3 1 0 3 3 3 0 AAA domain KxDL PF10241.4 ETO07017.1 - 0.11 12.4 1.9 0.68 9.8 0.2 2.9 2 0 0 2 2 2 0 Uncharacterized conserved protein AAA_33 PF13671.1 ETO07017.1 - 0.13 12.1 0.1 23 4.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain WD40 PF00400.27 ETO07018.1 - 1.5e-60 199.0 23.6 2.9e-12 45.9 0.0 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO07018.1 - 4.7e-11 41.5 2.9 0.018 13.1 0.0 4.5 2 1 1 4 4 4 3 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO07018.1 - 6.1e-06 26.5 1.1 6.1e-06 26.5 0.7 2.7 2 0 0 2 2 2 1 TRAF-type zinc finger DUF413 PF04219.7 ETO07018.1 - 0.084 12.6 1.1 0.19 11.5 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF Laminin_II PF06009.7 ETO07018.1 - 0.82 9.4 8.2 1.8 8.3 5.7 1.6 1 0 0 1 1 1 0 Laminin Domain II DUF1301 PF06979.7 ETO07019.1 - 5.2e-07 29.8 0.3 7.2e-07 29.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1301) SieB PF14163.1 ETO07019.1 - 0.1 12.1 0.6 0.15 11.6 0.4 1.3 1 0 0 1 1 1 0 Superinfection exclusion protein B Spc7 PF08317.6 ETO07021.1 - 0.0013 17.5 24.9 0.0017 17.0 6.3 2.2 2 0 0 2 2 2 2 Spc7 kinetochore protein DUF2838 PF10998.3 ETO07021.1 - 0.053 13.4 0.6 0.1 12.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2838) Flu_NS2 PF00601.14 ETO07021.1 - 0.068 13.3 13.0 0.098 12.8 2.4 2.8 2 0 0 2 2 2 0 Influenza non-structural protein (NS2) TMF_TATA_bd PF12325.3 ETO07021.1 - 0.15 11.7 19.5 0.49 10.1 0.1 3.5 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 ETO07021.1 - 2.8 7.5 19.6 0.8 9.2 3.9 2.6 2 1 0 2 2 2 0 IncA protein MFS_1 PF07690.11 ETO07024.1 - 3.7e-05 22.6 8.5 0.0098 14.6 6.2 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETO07024.1 - 0.00053 18.6 7.2 0.00053 18.6 5.0 1.8 1 1 1 2 2 2 1 Sugar (and other) transporter DNA_III_psi PF03603.8 ETO07025.1 - 0.0046 16.8 0.2 0.0088 15.9 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase III psi subunit Secretin_N_2 PF07655.8 ETO07025.1 - 0.51 10.7 4.8 1.3 9.4 0.0 2.6 2 0 0 2 2 2 0 Secretin N-terminal domain RasGAP PF00616.14 ETO07026.1 - 0.0038 16.9 2.4 0.0051 16.5 1.7 1.3 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase NARP1 PF12569.3 ETO07026.1 - 0.0089 14.8 8.4 0.011 14.5 5.8 1.1 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 HemX PF04375.9 ETO07026.1 - 0.011 14.3 2.4 0.015 13.9 1.7 1.1 1 0 0 1 1 1 0 HemX DUF4407 PF14362.1 ETO07026.1 - 0.012 14.6 2.0 0.014 14.3 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CotH PF08757.6 ETO07026.1 - 0.025 13.8 1.3 0.032 13.4 0.9 1.2 1 0 0 1 1 1 0 CotH protein Ycf1 PF05758.7 ETO07026.1 - 0.029 12.0 8.4 0.033 11.9 5.8 1.0 1 0 0 1 1 1 0 Ycf1 DUF2443 PF10398.4 ETO07026.1 - 0.04 13.7 0.3 0.13 12.1 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2443) NABP PF07990.7 ETO07026.1 - 0.053 12.7 0.3 0.054 12.7 0.2 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP Folate_carrier PF01770.13 ETO07026.1 - 0.058 11.8 1.7 0.078 11.4 1.2 1.2 1 0 0 1 1 1 0 Reduced folate carrier DUF3807 PF12720.2 ETO07026.1 - 0.059 13.5 9.9 0.077 13.1 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DDHD PF02862.12 ETO07026.1 - 0.067 12.9 6.3 0.078 12.7 4.3 1.1 1 0 0 1 1 1 0 DDHD domain Vfa1 PF08432.5 ETO07026.1 - 0.089 12.8 14.0 0.12 12.3 9.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1510 PF07423.6 ETO07026.1 - 0.11 11.8 9.1 0.14 11.5 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TUDOR PF00567.19 ETO07026.1 - 0.11 12.2 1.0 7.4 6.4 0.0 2.2 2 0 0 2 2 2 0 Tudor domain RR_TM4-6 PF06459.7 ETO07026.1 - 0.13 12.1 8.9 0.15 11.9 6.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM176 PF14851.1 ETO07026.1 - 0.23 11.1 3.9 0.3 10.7 2.7 1.2 1 0 0 1 1 1 0 FAM176 family V_ATPase_I PF01496.14 ETO07026.1 - 0.25 9.1 5.2 0.3 8.8 3.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Hom_end_hint PF05203.11 ETO07026.1 - 0.35 10.5 4.7 0.44 10.2 3.3 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint Tom37_C PF11801.3 ETO07026.1 - 0.37 10.6 5.6 0.52 10.1 3.9 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain TLP-20 PF06088.6 ETO07026.1 - 0.42 10.2 6.4 0.65 9.6 4.4 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) STAG PF08514.6 ETO07026.1 - 0.49 10.1 7.7 0.11 12.2 1.9 2.2 1 1 1 2 2 2 0 STAG domain DDRGK PF09756.4 ETO07026.1 - 0.61 9.4 14.9 0.9 8.9 10.3 1.2 1 0 0 1 1 1 0 DDRGK domain Neur_chan_memb PF02932.11 ETO07026.1 - 0.67 9.7 3.7 0.77 9.6 2.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SID-1_RNA_chan PF13965.1 ETO07026.1 - 0.72 7.9 4.2 0.88 7.6 2.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 HSP70 PF00012.15 ETO07026.1 - 0.76 7.6 7.4 0.87 7.4 5.1 1.0 1 0 0 1 1 1 0 Hsp70 protein Pox_RNA_Pol_19 PF05320.7 ETO07026.1 - 0.76 9.5 7.3 1.1 8.9 5.0 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Adeno_VII PF03228.9 ETO07026.1 - 4.3 7.9 7.2 6.8 7.3 5.0 1.2 1 0 0 1 1 1 0 Adenoviral core protein VII RNase_H PF00075.19 ETO07028.1 - 0.036 14.3 0.0 0.052 13.8 0.0 1.4 1 1 0 1 1 1 0 RNase H WD40 PF00400.27 ETO07029.1 - 1.3e-70 230.9 13.1 6.4e-12 44.8 0.0 7.0 6 0 0 6 6 6 6 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO07029.1 - 7e-06 25.9 0.5 0.38 11.0 0.0 4.3 3 1 1 4 4 4 2 Kelch motif Nup160 PF11715.3 ETO07029.1 - 0.00014 20.1 9.4 0.064 11.3 0.1 4.6 1 1 4 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO07029.1 - 0.00032 19.5 10.2 0.15 10.7 0.5 5.1 2 1 2 4 4 4 2 Nup133 N terminal like Resistin PF06954.6 ETO07029.1 - 0.0024 18.0 3.5 49 4.2 0.0 6.0 3 1 4 7 7 7 0 Resistin Kelch_5 PF13854.1 ETO07029.1 - 0.0031 17.4 0.1 16 5.6 0.0 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 ETO07029.1 - 0.2 11.2 0.0 0.2 11.2 0.0 3.5 4 0 0 4 4 4 0 Kelch motif Methyltransf_28 PF02636.12 ETO07030.1 - 1.9e-36 125.7 0.0 2.7e-36 125.2 0.0 1.3 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Rtf2 PF04641.7 ETO07031.1 - 0.0094 15.1 4.8 0.01 15.0 3.3 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger YqfQ PF14181.1 ETO07031.1 - 0.014 15.4 3.5 0.016 15.2 2.5 1.1 1 0 0 1 1 1 0 YqfQ-like protein Tim54 PF11711.3 ETO07031.1 - 0.019 13.5 1.1 0.02 13.5 0.7 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Peroxin-13_N PF04088.8 ETO07031.1 - 0.035 14.0 0.9 0.047 13.6 0.6 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region MHC2-interact PF09307.5 ETO07031.1 - 0.056 13.2 0.7 0.083 12.6 0.5 1.4 1 0 0 1 1 1 0 CLIP, MHC2 interacting BTV_NS2 PF04514.7 ETO07031.1 - 0.067 12.0 3.6 0.081 11.8 2.5 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 SR-25 PF10500.4 ETO07031.1 - 0.1 12.0 10.4 0.12 11.8 7.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3464 PF11947.3 ETO07031.1 - 0.12 11.8 3.8 0.17 11.3 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) BLVR PF06375.6 ETO07031.1 - 0.12 12.1 12.1 0.16 11.8 8.4 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Caldesmon PF02029.10 ETO07031.1 - 0.13 10.6 11.7 0.13 10.6 8.1 1.0 1 0 0 1 1 1 0 Caldesmon PEX11 PF05648.9 ETO07031.1 - 0.15 11.3 0.8 0.19 11.0 0.6 1.3 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Peptidase_S49_N PF08496.5 ETO07031.1 - 0.15 11.8 7.8 0.18 11.5 5.4 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1510 PF07423.6 ETO07031.1 - 0.19 11.0 8.9 0.23 10.7 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RNA_pol_3_Rpc31 PF11705.3 ETO07031.1 - 0.21 11.4 8.7 0.26 11.2 6.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Ycf1 PF05758.7 ETO07031.1 - 0.22 9.2 6.5 0.24 9.1 4.5 1.0 1 0 0 1 1 1 0 Ycf1 LicD PF04991.8 ETO07031.1 - 0.38 10.8 4.4 0.44 10.6 3.1 1.1 1 0 0 1 1 1 0 LicD family EIIBC-GUT_N PF03612.9 ETO07031.1 - 0.52 9.8 2.4 0.62 9.6 1.7 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus RAP1 PF07218.6 ETO07031.1 - 0.62 8.0 6.6 0.61 8.1 4.6 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) HSP90 PF00183.13 ETO07031.1 - 0.82 7.9 10.5 0.93 7.8 7.3 1.0 1 0 0 1 1 1 0 Hsp90 protein NARP1 PF12569.3 ETO07031.1 - 0.91 8.1 9.9 0.98 8.0 6.9 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 OAD_gamma PF04277.8 ETO07031.1 - 1.2 9.5 3.4 1.6 9.1 2.4 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Vfa1 PF08432.5 ETO07031.1 - 1.5 8.8 14.5 2 8.4 10.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Sec62 PF03839.11 ETO07031.1 - 3.3 7.0 8.8 4 6.7 6.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 U79_P34 PF03064.11 ETO07031.1 - 4.1 6.8 9.2 5.1 6.5 6.4 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CUE PF02845.11 ETO07033.1 - 0.013 14.9 0.3 0.035 13.6 0.2 1.7 1 1 0 1 1 1 0 CUE domain SRP-alpha_N PF04086.8 ETO07033.1 - 0.16 11.3 4.9 0.15 11.4 1.8 1.8 1 1 1 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal DUF4252 PF14060.1 ETO07033.1 - 0.23 10.9 5.5 0.33 10.4 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4252) Syntaxin_2 PF14523.1 ETO07033.1 - 0.93 9.5 5.3 2 8.5 1.1 2.3 2 0 0 2 2 2 0 Syntaxin-like protein WD40 PF00400.27 ETO07034.1 - 6.9e-25 85.9 8.2 1.2e-08 34.4 0.0 3.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO07034.1 - 0.0006 18.0 0.2 0.0079 14.3 0.0 2.4 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Kelch_4 PF13418.1 ETO07036.1 - 5.3e-05 22.8 0.1 0.0012 18.5 0.0 2.7 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO07036.1 - 0.00044 19.7 0.5 0.001 18.5 0.3 1.6 1 0 0 1 1 1 1 Kelch motif Kelch_3 PF13415.1 ETO07036.1 - 0.0052 16.9 0.1 0.046 13.9 0.1 2.5 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO07036.1 - 0.022 14.5 0.1 0.058 13.1 0.1 1.7 1 0 0 1 1 1 0 Kelch motif Kelch_5 PF13854.1 ETO07036.1 - 0.056 13.4 0.2 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Kelch motif Kelch_6 PF13964.1 ETO07036.1 - 0.064 13.4 0.7 0.064 13.4 0.5 2.4 3 0 0 3 3 3 0 Kelch motif tRNA-synt_1c PF00749.16 ETO07037.1 - 1.5e-38 132.2 0.0 1.5e-38 132.2 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1e PF01406.14 ETO07037.1 - 0.0049 16.0 0.1 0.0049 16.0 0.0 2.3 2 1 1 3 3 3 1 tRNA synthetases class I (C) catalytic domain ATG27 PF09451.5 ETO07037.1 - 0.011 14.9 2.6 0.017 14.3 1.8 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 DUF4591 PF15261.1 ETO07038.1 - 3.2e-05 24.2 12.6 0.026 14.7 0.1 3.3 3 0 0 3 3 3 3 Domain of unknown function (DUF4591) Bin3 PF06859.7 ETO07039.1 - 1e-09 38.3 0.2 5e-08 32.9 0.0 2.1 2 0 0 2 2 2 2 Bicoid-interacting protein 3 (Bin3) FAM176 PF14851.1 ETO07039.1 - 0.041 13.5 0.2 0.047 13.3 0.1 1.2 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.5 ETO07039.1 - 0.47 10.7 5.6 0.29 11.4 2.7 1.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF4407 PF14362.1 ETO07042.1 - 0.39 9.6 18.7 0.48 9.3 3.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FtsK_SpoIIIE_N PF12538.3 ETO07042.1 - 2.7 8.1 8.6 0.54 10.3 1.1 2.4 2 0 0 2 2 2 0 DNA transporter dCMP_cyt_deam_1 PF00383.17 ETO07043.1 - 1.1e-26 92.4 0.4 2.3e-26 91.3 0.0 1.8 2 1 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 ETO07043.1 - 0.023 14.2 0.2 0.053 13.1 0.1 1.5 1 0 0 1 1 1 0 APOBEC-like N-terminal domain zf-NPL4 PF05020.10 ETO07045.1 - 0.023 14.3 0.2 0.033 13.8 0.2 1.3 1 0 0 1 1 1 0 NPL4 family, putative zinc binding region YebO PF13974.1 ETO07045.1 - 0.076 12.8 0.1 0.2 11.4 0.0 1.8 1 1 0 1 1 1 0 YebO-like protein TPR_12 PF13424.1 ETO07046.1 - 4.8e-41 138.5 15.2 6.1e-15 54.9 0.0 6.0 2 2 3 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETO07046.1 - 8.9e-28 95.7 23.9 2.2e-08 33.5 1.6 5.3 3 2 2 5 5 5 5 TPR repeat TPR_1 PF00515.23 ETO07046.1 - 1.1e-24 85.0 33.0 8.3e-05 22.0 0.0 9.0 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.12 ETO07046.1 - 6.7e-23 78.7 24.5 0.00033 20.3 0.0 9.0 7 2 2 9 9 9 6 Tetratricopeptide repeat TPR_10 PF13374.1 ETO07046.1 - 5.2e-14 51.6 0.3 0.046 13.6 0.0 6.0 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO07046.1 - 5.4e-14 50.8 14.7 0.00046 19.7 0.0 7.8 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO07046.1 - 2.1e-09 36.4 32.5 0.031 14.0 0.7 8.1 8 1 1 9 9 8 4 Tetratricopeptide repeat TPR_6 PF13174.1 ETO07046.1 - 3.9e-09 36.3 11.7 7.1 7.3 0.1 8.1 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETO07046.1 - 1.4e-08 34.6 0.0 1.8 9.4 0.0 6.5 6 2 2 8 8 6 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO07046.1 - 7.5e-08 32.4 27.7 0.0019 18.2 0.2 4.7 3 1 3 6 6 5 3 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.1 ETO07046.1 - 1.5e-07 30.8 20.5 4.1e-05 22.8 5.2 4.0 1 1 2 4 4 4 3 Soluble NSF attachment protein, SNAP TPR_16 PF13432.1 ETO07046.1 - 8e-07 29.5 0.3 0.86 10.3 0.1 5.5 4 2 1 5 5 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO07046.1 - 1.1e-06 27.7 1.4 1.7 7.9 0.0 5.7 6 0 0 6 6 6 2 SHNi-TPR TPR_17 PF13431.1 ETO07046.1 - 9.8e-06 25.3 22.1 0.45 10.8 0.2 7.9 9 2 2 11 11 9 3 Tetratricopeptide repeat MIT PF04212.13 ETO07046.1 - 5.6e-05 22.9 3.4 0.85 9.5 0.0 5.4 4 1 0 4 4 4 1 MIT (microtubule interacting and transport) domain Apc5 PF12862.2 ETO07046.1 - 0.0039 16.9 6.0 0.43 10.4 0.1 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 RHD PF00554.17 ETO07046.1 - 0.025 14.3 0.1 0.24 11.1 0.0 2.3 3 0 0 3 3 2 0 Rel homology domain (RHD) Elf1 PF05129.8 ETO07046.1 - 0.028 14.1 0.3 17 5.1 0.0 3.4 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like SLT PF01464.15 ETO07046.1 - 0.12 11.8 4.1 0.5 9.8 0.2 3.0 3 0 0 3 3 3 0 Transglycosylase SLT domain Sel1 PF08238.7 ETO07046.1 - 0.2 12.3 5.4 1.5 9.5 0.0 3.9 4 0 0 4 4 4 0 Sel1 repeat SusD PF07980.6 ETO07046.1 - 0.8 9.1 5.6 1.2 8.6 3.8 1.4 1 1 0 1 1 1 0 SusD family AIPR PF10592.4 ETO07046.1 - 3 7.0 11.1 2.2 7.5 3.4 2.1 1 1 1 2 2 2 0 AIPR protein NSF PF02071.15 ETO07046.1 - 5.1 8.1 9.5 17 6.5 0.0 5.2 5 0 0 5 5 3 0 Aromatic-di-Alanine (AdAR) repeat DUF1794 PF08768.6 ETO07048.1 - 2e-27 95.9 0.0 3.5e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) Viral_Beta_CD PF04530.7 ETO07048.1 - 0.029 14.5 0.2 0.084 13.0 0.1 1.8 1 0 0 1 1 1 0 Viral Beta C/D like family RMMBL PF07521.7 ETO07051.1 - 1.4e-08 34.3 0.4 1.4e-07 31.2 0.0 2.2 2 0 0 2 2 2 1 RNA-metabolising metallo-beta-lactamase Beta-Casp PF10996.3 ETO07051.1 - 1.6e-06 28.0 0.0 3.4e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain DUF362 PF04015.7 ETO07051.1 - 0.013 14.9 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF362) Bromo_MP PF01573.11 ETO07053.1 - 0.00048 19.2 0.3 0.00055 19.0 0.2 1.1 1 0 0 1 1 1 1 Bromovirus movement protein AKNA PF12443.3 ETO07054.1 - 0.0075 16.2 1.5 0.012 15.5 1.0 1.4 1 0 0 1 1 1 1 AT-hook-containing transcription factor Spc24 PF08286.6 ETO07054.1 - 0.012 15.3 3.8 0.022 14.4 2.6 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 COX6A PF02046.10 ETO07054.1 - 0.073 12.9 0.5 0.13 12.1 0.2 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase subunit VIa DUF2681 PF10883.3 ETO07054.1 - 0.092 12.9 4.4 0.19 11.9 3.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Metallothi_Euk2 PF12809.2 ETO07054.1 - 0.13 12.7 0.3 0.21 11.9 0.2 1.3 1 0 0 1 1 1 0 Eukaryotic metallothionein Peptidase_S49_N PF08496.5 ETO07054.1 - 0.96 9.2 4.7 1.6 8.4 3.3 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Med3 PF11593.3 ETO07055.1 - 0.0031 16.8 56.5 0.0045 16.2 38.5 1.5 1 1 0 1 1 1 1 Mediator complex subunit 3 fungal SAP PF02037.22 ETO07057.1 - 1.5e-10 40.3 0.3 3.1e-10 39.3 0.2 1.6 1 0 0 1 1 1 1 SAP domain Agouti PF05039.7 ETO07057.1 - 0.39 11.1 2.6 1.4 9.3 1.5 2.2 1 1 0 1 1 1 0 Agouti protein RHD PF00554.17 ETO07057.1 - 0.57 9.9 3.9 25 4.5 2.7 2.1 1 1 0 1 1 1 0 Rel homology domain (RHD) XPG_N PF00752.12 ETO07058.1 - 2.5e-23 82.2 0.1 5e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 ETO07058.1 - 1.8e-15 56.7 0.1 4.5e-15 55.4 0.1 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 ETO07058.1 - 4.4e-08 33.2 0.0 3.3e-07 30.4 0.0 2.3 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold DUF3610 PF12272.3 ETO07058.1 - 0.12 11.9 1.7 8.2 6.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3610) RSN1_TM PF13967.1 ETO07060.1 - 5.2e-26 91.0 0.6 1.2e-25 89.9 0.4 1.6 1 1 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4013 PF13197.1 ETO07060.1 - 0.0098 15.2 1.5 0.019 14.3 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4013) Ctr PF04145.10 ETO07060.1 - 0.014 15.4 0.3 0.078 13.0 0.0 2.0 2 0 0 2 2 2 0 Ctr copper transporter family Aldo_ket_red PF00248.16 ETO07061.1 - 1.6e-26 92.7 0.0 2e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family zf-C3HC4_3 PF13920.1 ETO07062.1 - 6.9e-12 44.8 10.0 1.4e-11 43.8 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO07062.1 - 1.7e-05 24.7 13.7 4.5e-05 23.3 9.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SAM_1 PF00536.25 ETO07062.1 - 0.00028 20.9 0.3 0.00054 20.0 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-RING_5 PF14634.1 ETO07062.1 - 0.0016 18.1 10.5 0.0037 16.9 7.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain UBA_2 PF08587.6 ETO07062.1 - 0.0063 16.6 0.2 1.5 9.0 0.0 2.8 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) zf-RING_2 PF13639.1 ETO07062.1 - 0.38 10.6 11.1 1.3 8.9 7.7 2.0 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.1 ETO07062.1 - 1.2 8.6 10.2 0.36 10.4 4.4 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.20 ETO07062.1 - 2.9 7.6 13.2 8.7 6.1 9.2 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DpnII PF04556.7 ETO07064.1 - 0.0075 15.3 2.6 0.015 14.4 1.8 1.4 1 0 0 1 1 1 1 DpnII restriction endonuclease Baculo_p24 PF05073.7 ETO07064.1 - 0.14 11.7 5.8 0.07 12.6 2.0 1.9 1 1 1 2 2 2 0 Baculovirus P24 capsid protein YlqD PF11068.3 ETO07064.1 - 0.17 11.9 15.3 0.042 13.8 7.8 1.9 2 0 0 2 2 2 0 YlqD protein AAA_14 PF13173.1 ETO07066.1 - 0.00014 21.7 0.0 0.00026 20.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 ETO07066.1 - 0.00066 19.9 0.4 0.0015 18.8 0.0 1.7 2 1 0 2 2 2 1 ABC transporter T2SE PF00437.15 ETO07066.1 - 0.0012 17.8 0.0 0.0013 17.6 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein RNA_helicase PF00910.17 ETO07066.1 - 0.0015 18.7 0.0 0.0026 17.9 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Arch_ATPase PF01637.13 ETO07066.1 - 0.0026 17.5 0.0 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 ETO07066.1 - 0.0042 17.2 0.0 0.0078 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 ETO07066.1 - 0.0043 16.2 0.0 0.0063 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 ETO07066.1 - 0.01 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.1 ETO07066.1 - 0.016 16.0 0.0 0.028 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 ETO07066.1 - 0.02 14.7 0.5 0.15 11.9 0.0 2.4 2 1 1 3 3 3 0 AAA domain AAA PF00004.24 ETO07066.1 - 0.025 14.7 0.0 0.063 13.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 ETO07066.1 - 0.027 14.4 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.9 ETO07066.1 - 0.041 13.6 0.0 0.098 12.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 ETO07066.1 - 0.042 13.4 1.5 0.11 12.1 0.0 2.0 1 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 ETO07066.1 - 0.046 13.7 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 ETO07066.1 - 0.048 13.3 0.0 0.087 12.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Rad17 PF03215.10 ETO07066.1 - 0.061 12.0 0.7 0.098 11.3 0.0 1.6 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein MobB PF03205.9 ETO07066.1 - 0.062 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ResIII PF04851.10 ETO07066.1 - 0.078 12.8 1.2 0.28 10.9 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.7 ETO07066.1 - 0.083 11.9 0.4 0.14 11.1 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_29 PF13555.1 ETO07066.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NAM-associated PF14303.1 ETO07066.1 - 0.22 11.8 6.8 0.03 14.6 1.7 1.6 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Protocadherin PF08374.6 ETO07066.1 - 0.42 10.2 5.1 0.23 11.0 2.0 1.6 1 1 0 1 1 1 0 Protocadherin NST1 PF13945.1 ETO07066.1 - 5 7.1 10.9 1.1 9.3 4.3 1.9 2 0 0 2 2 2 0 Salt tolerance down-regulator HAP2-GCS1 PF10699.4 ETO07067.1 - 0.054 13.4 0.1 1.9 8.5 0.0 2.4 2 0 0 2 2 2 0 Male gamete fusion factor TLE_N PF03920.10 ETO07068.1 - 0.084 12.6 0.3 0.12 12.1 0.2 1.2 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain PUB PF09409.5 ETO07069.1 - 2e-05 24.2 0.6 3.8e-05 23.3 0.4 1.5 1 0 0 1 1 1 1 PUB domain RHH_2 PF03693.9 ETO07069.1 - 0.0037 17.3 0.0 0.0083 16.2 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0156) MepB PF08877.5 ETO07069.1 - 0.099 12.1 0.1 0.52 9.8 0.0 2.0 1 1 1 2 2 2 0 MepB protein Kelch_6 PF13964.1 ETO07070.1 - 0.00012 22.1 0.1 0.0084 16.2 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETO07070.1 - 0.00038 20.1 0.0 0.81 9.5 0.0 2.6 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO07070.1 - 0.0061 16.4 0.0 0.59 10.1 0.1 2.6 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.20 ETO07070.1 - 0.026 14.0 0.0 1.5 8.4 0.0 3.0 2 0 0 2 2 2 0 Kelch motif WD40 PF00400.27 ETO07071.1 - 8.9e-156 500.9 58.1 2.2e-13 49.5 0.1 15.5 15 0 0 15 15 15 14 WD domain, G-beta repeat Nup160 PF11715.3 ETO07071.1 - 3.5e-12 45.2 23.8 0.00058 18.1 0.2 10.4 1 1 6 8 8 8 6 Nucleoporin Nup120/160 NACHT PF05729.7 ETO07071.1 - 1.6e-09 37.6 0.0 4.8e-09 36.0 0.0 1.9 1 0 0 1 1 1 1 NACHT domain Pentapeptide PF00805.17 ETO07071.1 - 8.5e-08 31.2 0.9 2.2e-07 29.9 0.6 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Str_synth PF03088.11 ETO07071.1 - 1.2e-06 28.4 1.4 1.2 9.2 0.0 7.2 6 3 4 10 10 9 1 Strictosidine synthase PQQ_2 PF13360.1 ETO07071.1 - 2.4e-06 27.2 1.2 0.012 15.0 0.0 3.8 1 1 1 3 3 3 2 PQQ-like domain Cytochrom_D1 PF02239.11 ETO07071.1 - 2.4e-06 26.0 6.8 1.2 7.3 0.0 6.1 2 1 5 7 7 7 2 Cytochrome D1 heme domain AAA_18 PF13238.1 ETO07071.1 - 1.4e-05 25.3 0.0 7.5e-05 23.0 0.0 2.3 1 0 0 1 1 1 1 AAA domain Pentapeptide_4 PF13599.1 ETO07071.1 - 5e-05 23.0 0.1 0.00014 21.6 0.1 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Gmad1 PF10647.4 ETO07071.1 - 0.0001 21.8 0.0 0.057 12.8 0.0 4.1 5 0 0 5 5 5 1 Lipoprotein LpqB beta-propeller domain DUF1258 PF06869.7 ETO07071.1 - 0.00012 21.2 11.9 1.5 7.8 0.0 6.1 5 2 2 8 8 8 2 Protein of unknown function (DUF1258) AAA_22 PF13401.1 ETO07071.1 - 0.00046 20.3 0.0 0.0017 18.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain BBS2_Mid PF14783.1 ETO07071.1 - 0.002 17.8 0.8 1.6 8.5 0.0 6.0 6 1 1 7 7 6 1 Ciliary BBSome complex subunit 2, middle region DUF3601 PF12208.3 ETO07071.1 - 0.0034 17.2 0.0 3 7.8 0.0 5.6 6 1 1 7 7 6 1 Domain of unknown function (DUF3601) Pentapeptide_3 PF13576.1 ETO07071.1 - 0.004 16.9 0.4 0.004 16.9 0.3 2.3 2 1 0 2 2 1 1 Pentapeptide repeats (9 copies) AAA_17 PF13207.1 ETO07071.1 - 0.0047 17.7 0.0 0.025 15.3 0.0 2.3 1 0 0 1 1 1 1 AAA domain CsgF PF10614.4 ETO07071.1 - 0.03 14.3 0.7 8.7 6.3 0.0 4.2 4 0 0 4 4 4 0 Type VIII secretion system (T8SS), CsgF protein PD40 PF07676.7 ETO07071.1 - 0.24 11.0 31.1 4.9 6.9 0.1 9.7 11 0 0 11 11 11 0 WD40-like Beta Propeller Repeat CUE PF02845.11 ETO07072.1 - 0.0009 18.6 0.0 0.0016 17.8 0.0 1.5 1 0 0 1 1 1 1 CUE domain Oxidored_q1_N PF00662.15 ETO07073.1 - 0.017 14.6 1.1 0.047 13.2 0.1 2.0 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus ASFV_J13L PF05568.6 ETO07073.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein SecD-TM1 PF13721.1 ETO07073.1 - 0.21 11.8 4.0 0.44 10.8 0.1 2.3 2 0 0 2 2 2 0 SecD export protein N-terminal TM region Dppa2_A PF14049.1 ETO07073.1 - 1.6 8.6 7.4 0.5 10.2 2.5 2.0 1 1 1 2 2 2 0 Dppa2/4 conserved region in higher vertebrates Tom37_C PF11801.3 ETO07073.1 - 2.1 8.1 5.9 4.5 7.1 4.1 1.5 1 0 0 1 1 1 0 Tom37 C-terminal domain DDHD PF02862.12 ETO07073.1 - 4 7.1 7.0 6.5 6.4 4.8 1.3 1 0 0 1 1 1 0 DDHD domain NARP1 PF12569.3 ETO07073.1 - 5.1 5.7 15.1 7.4 5.1 10.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Striatin PF08232.7 ETO07073.1 - 7.6 6.8 11.0 14 5.9 7.7 1.4 1 0 0 1 1 1 0 Striatin family TLD PF07534.11 ETO07077.1 - 0.025 14.5 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 TLD WD40 PF00400.27 ETO07079.1 - 1.4e-12 46.9 4.1 3.1e-10 39.5 0.1 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO07079.1 - 0.019 13.1 0.1 0.11 10.5 0.0 1.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 CRM1_C PF08767.6 ETO07081.1 - 0.011 14.6 2.0 0.038 12.8 0.3 1.9 1 1 1 2 2 2 0 CRM1 C terminal DUF1132 PF06575.7 ETO07081.1 - 0.13 12.5 1.9 0.24 11.6 1.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1132) DUF2660 PF10859.3 ETO07081.1 - 0.23 11.6 1.7 0.35 11.1 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) Polysacc_synt_4 PF04669.8 ETO07083.1 - 0.024 14.0 0.2 0.03 13.6 0.2 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis DUF943 PF06092.7 ETO07083.1 - 1.5 8.0 6.4 0.27 10.5 0.6 2.0 2 0 0 2 2 2 0 Enterobacterial putative membrane protein (DUF943) Choline_sulf_C PF12411.3 ETO07084.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Choline sulfatase enzyme C terminal RPEL PF02755.10 ETO07085.1 - 1.8e-12 46.1 19.1 2.7e-05 23.3 0.0 5.6 5 0 0 5 5 5 3 RPEL repeat DUF2203 PF09969.4 ETO07085.1 - 0.24 11.6 7.2 0.99 9.6 0.0 3.6 3 2 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) RPEL PF02755.10 ETO07086.1 - 7.8e-06 25.0 8.4 0.19 11.1 1.1 5.0 4 0 0 4 4 4 3 RPEL repeat RVT_1 PF00078.22 ETO07087.1 - 4.8e-09 35.8 0.5 2.7e-07 30.1 0.1 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2164 PF09932.4 ETO07087.1 - 0.039 13.7 0.3 4.8 7.0 0.1 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2164) DDE_3 PF13358.1 ETO07088.1 - 1.3e-15 57.3 0.3 1.4e-15 57.2 0.2 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 ETO07088.1 - 0.0025 17.9 0.0 0.0026 17.8 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain Dfp1_Him1_M PF08630.5 ETO07088.1 - 0.051 13.3 0.5 0.051 13.3 0.3 1.5 1 1 0 1 1 1 0 Dfp1/Him1, central region N6_N4_Mtase PF01555.13 ETO07088.1 - 0.27 10.6 2.6 0.27 10.7 1.8 1.0 1 0 0 1 1 1 0 DNA methylase DUF1863 PF08937.6 ETO07090.1 - 0.25 11.4 11.9 0.24 11.4 3.7 2.9 4 0 0 4 4 4 0 MTH538 TIR-like domain (DUF1863) Peptidase_S49_N PF08496.5 ETO07090.1 - 0.29 10.9 6.1 0.72 9.6 4.2 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RVT_1 PF00078.22 ETO07091.1 - 4.5e-06 26.1 0.2 4e-05 23.0 0.2 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Med9 PF07544.8 ETO07091.1 - 0.0076 15.9 5.4 0.0076 15.9 3.7 3.3 3 1 0 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 Uds1 PF15456.1 ETO07091.1 - 0.5 10.3 13.4 0.18 11.7 5.0 2.4 1 1 1 2 2 2 0 Up-regulated During Septation DUF382 PF04037.8 ETO07092.1 - 0.066 13.0 2.6 0.47 10.2 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF382) Reo_sigmaC PF04582.7 ETO07093.1 - 0.00079 18.7 5.3 0.0016 17.6 2.8 1.8 1 1 1 2 2 2 2 Reovirus sigma C capsid protein APG6 PF04111.7 ETO07093.1 - 0.0084 15.1 34.5 0.034 13.1 12.4 2.0 1 1 1 2 2 2 2 Autophagy protein Apg6 ERM PF00769.14 ETO07093.1 - 0.027 13.9 30.6 0.041 13.4 21.2 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ADIP PF11559.3 ETO07093.1 - 0.037 13.9 27.6 0.038 13.8 10.5 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding RasGAP_C PF03836.10 ETO07093.1 - 0.043 13.4 21.9 0.81 9.3 2.8 2.1 1 1 1 2 2 2 0 RasGAP C-terminus IncA PF04156.9 ETO07093.1 - 0.045 13.3 32.5 0.4 10.2 10.1 2.0 1 1 1 2 2 2 0 IncA protein IFT57 PF10498.4 ETO07093.1 - 0.056 12.1 22.9 0.066 11.9 15.9 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF2951 PF11166.3 ETO07093.1 - 0.071 12.9 21.9 0.041 13.7 10.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) EzrA PF06160.7 ETO07093.1 - 0.075 11.2 25.8 1.8 6.6 17.6 1.9 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Tropomyosin_1 PF12718.2 ETO07093.1 - 0.076 12.8 37.1 0.52 10.1 7.2 2.1 1 1 1 2 2 2 0 Tropomyosin like DUF1664 PF07889.7 ETO07093.1 - 0.11 12.3 20.4 0.32 10.7 4.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Synaptonemal_3 PF15191.1 ETO07093.1 - 0.12 12.0 12.4 1.4 8.7 2.9 2.4 2 1 0 2 2 2 0 Synaptonemal complex central element protein 3 Baculo_PEP_C PF04513.7 ETO07093.1 - 0.13 12.1 4.5 0.78 9.5 2.7 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 ETO07093.1 - 0.13 10.9 28.7 0.7 8.5 9.5 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.4 ETO07093.1 - 0.13 12.1 38.0 0.99 9.2 13.8 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin_2 PF01920.15 ETO07093.1 - 0.14 11.9 41.6 0.26 11.0 8.5 4.0 1 1 3 4 4 4 0 Prefoldin subunit Hemerythrin PF01814.18 ETO07093.1 - 0.24 11.5 3.1 1.1 9.4 0.4 2.1 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain CALCOCO1 PF07888.6 ETO07093.1 - 0.33 9.1 23.9 0.37 9.0 16.6 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like NTR2 PF15458.1 ETO07093.1 - 0.43 9.7 25.3 0.58 9.3 2.2 2.6 2 1 0 3 3 3 0 Nineteen complex-related protein 2 Nsp1_C PF05064.8 ETO07093.1 - 0.43 10.2 21.6 0.29 10.7 6.0 2.3 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF3584 PF12128.3 ETO07093.1 - 0.44 7.8 24.2 0.55 7.4 16.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF677 PF05055.7 ETO07093.1 - 0.44 9.1 18.5 1.2 7.7 12.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF677) Cep57_CLD PF14073.1 ETO07093.1 - 0.46 10.2 28.7 0.6 9.9 19.9 1.0 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 Herpes_UL6 PF01763.11 ETO07093.1 - 0.48 8.5 17.4 0.63 8.1 12.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Fib_alpha PF08702.5 ETO07093.1 - 0.48 10.5 20.4 1.9 8.6 14.2 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4337 PF14235.1 ETO07093.1 - 0.49 10.2 23.5 0.16 11.8 3.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Bacillus_HBL PF05791.6 ETO07093.1 - 0.57 9.5 19.7 0.061 12.7 7.1 2.1 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) TEX13 PF15186.1 ETO07093.1 - 0.67 9.5 17.6 0.74 9.3 4.9 2.1 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family DUF4164 PF13747.1 ETO07093.1 - 0.79 9.8 20.8 0.93 9.6 5.5 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) DUF3450 PF11932.3 ETO07093.1 - 0.86 8.8 19.4 1.3 8.2 12.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4509 PF14970.1 ETO07093.1 - 1.1 8.8 10.2 2.3 7.8 1.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4509) DUF4200 PF13863.1 ETO07093.1 - 1.4 8.8 36.1 0.3 11.0 12.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) CCDC155 PF14662.1 ETO07093.1 - 1.5 8.3 31.9 9.1 5.8 22.2 1.9 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 Laminin_II PF06009.7 ETO07093.1 - 1.6 8.4 18.4 2.9 7.6 5.6 2.1 1 1 1 2 2 2 0 Laminin Domain II DUF3708 PF12501.3 ETO07093.1 - 1.7 8.4 4.2 0.93 9.3 0.8 1.8 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter AAA_13 PF13166.1 ETO07093.1 - 1.7 7.0 24.4 2.9 6.2 16.9 1.4 1 1 0 1 1 1 0 AAA domain UPF0184 PF03670.8 ETO07093.1 - 1.8 8.7 9.6 1.8 8.7 1.5 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) Seryl_tRNA_N PF02403.17 ETO07093.1 - 2.2 8.3 30.1 0.49 10.4 11.5 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4140 PF13600.1 ETO07093.1 - 2.3 8.7 19.4 0.18 12.2 4.6 2.9 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) Strep_SA_rep PF06696.6 ETO07093.1 - 2.6 7.9 5.7 0.56 10.0 1.2 2.1 2 0 0 2 2 1 0 Streptococcal surface antigen repeat DUF2400 PF09674.5 ETO07093.1 - 2.7 7.6 10.5 4.9 6.7 7.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2400) Z1 PF10593.4 ETO07093.1 - 2.8 7.1 10.8 3.5 6.7 7.5 1.2 1 0 0 1 1 1 0 Z1 domain DUF972 PF06156.8 ETO07093.1 - 3.2 8.1 26.4 2.4 8.5 11.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Mnd1 PF03962.10 ETO07093.1 - 3.4 7.3 30.0 33 4.0 20.8 2.1 1 1 0 1 1 1 0 Mnd1 family DUF489 PF04356.7 ETO07093.1 - 3.5 7.1 8.1 4.8 6.7 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF489) GAS PF13851.1 ETO07093.1 - 3.5 6.7 34.5 0.66 9.1 13.3 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding ArdA PF07275.6 ETO07093.1 - 3.6 7.8 11.2 0.74 10.0 4.2 1.9 1 1 1 2 2 2 0 Antirestriction protein (ArdA) YjcZ PF13990.1 ETO07093.1 - 3.7 6.6 10.5 5.4 6.0 7.3 1.4 1 0 0 1 1 1 0 YjcZ-like protein Silic_transp PF03842.8 ETO07093.1 - 5 5.0 8.9 6.7 4.6 6.2 1.2 1 0 0 1 1 1 0 Silicon transporter Herpes_UL25 PF01499.11 ETO07093.1 - 5.2 5.2 14.2 0.8 7.9 7.1 1.6 1 1 1 2 2 2 0 Herpesvirus UL25 family Allexi_40kDa PF05549.6 ETO07093.1 - 5.2 6.2 17.2 1.6 7.9 5.3 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein TMF_TATA_bd PF12325.3 ETO07093.1 - 5.4 6.7 32.3 5.9 6.6 6.5 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding BLOC1_2 PF10046.4 ETO07093.1 - 6 7.0 21.6 17 5.6 5.2 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2968 PF11180.3 ETO07093.1 - 6.1 6.1 19.1 2 7.7 6.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF4559 PF15112.1 ETO07093.1 - 6.2 5.8 21.3 11 5.0 14.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) Peptidase_S46 PF10459.4 ETO07093.1 - 6.3 5.0 16.9 0.2 10.0 2.2 1.9 1 1 1 2 2 2 0 Peptidase S46 ATG16 PF08614.6 ETO07093.1 - 6.8 6.4 27.8 16 5.2 19.2 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Ax_dynein_light PF10211.4 ETO07093.1 - 8.4 6.1 33.4 0.34 10.7 12.2 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain DUF812 PF05667.6 ETO07093.1 - 9.9 4.5 28.4 19 3.5 19.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Syntaxin-6_N PF09177.6 ETO07093.1 - 10 6.6 16.9 19 5.7 1.0 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Glyco_transf_25 PF01755.12 ETO07094.1 - 0.034 13.7 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) NIF PF03031.13 ETO07095.1 - 4.2e-36 124.0 0.0 6.3e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Helicase_RecD PF05127.9 ETO07095.1 - 0.0031 17.1 2.1 0.0049 16.5 1.4 1.3 1 0 0 1 1 1 1 Helicase RbsD_FucU PF05025.8 ETO07095.1 - 0.011 15.9 3.5 0.74 10.1 0.0 2.2 1 1 1 2 2 2 0 RbsD / FucU transport protein family Pex14_N PF04695.8 ETO07095.1 - 0.016 15.2 3.8 0.03 14.3 2.6 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HAD_2 PF13419.1 ETO07095.1 - 0.046 13.9 0.0 0.057 13.6 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Dicty_REP PF05086.7 ETO07095.1 - 0.06 11.0 7.6 0.073 10.8 5.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AIF_C PF14721.1 ETO07095.1 - 0.14 12.3 1.3 0.22 11.7 0.9 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term TFIIA PF03153.8 ETO07095.1 - 0.78 9.5 6.8 0.99 9.2 4.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Acid_phosphat_B PF03767.9 ETO07095.1 - 0.82 8.9 6.0 0.6 9.4 3.1 1.5 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Peptidase_M1 PF01433.15 ETO07096.1 - 1.4e-28 100.0 0.3 1.4e-19 70.4 0.0 2.0 1 1 1 2 2 2 2 Peptidase family M1 Stc1 PF12898.2 ETO07097.1 - 0.00073 19.5 0.8 0.0014 18.6 0.5 1.5 1 0 0 1 1 1 1 Stc1 domain Glyco_hydro_92 PF07971.7 ETO07097.1 - 0.041 12.5 0.6 0.055 12.1 0.4 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 92 IR1-M PF12185.3 ETO07098.1 - 0.0088 15.7 0.5 4.6 7.0 0.0 2.6 2 0 0 2 2 2 2 Nup358/RanBP2 E3 ligase domain Snapin_Pallidin PF14712.1 ETO07100.1 - 0.57 10.5 4.9 0.62 10.4 1.5 2.0 2 0 0 2 2 2 0 Snapin/Pallidin DUF3680 PF12441.3 ETO07101.1 - 0.0083 15.9 1.8 0.022 14.6 1.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3680) DUF872 PF05915.7 ETO07101.1 - 0.057 13.2 0.0 0.072 12.9 0.0 1.3 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) FtsJ PF01728.14 ETO07102.1 - 7.1e-31 107.5 0.1 1.7e-30 106.3 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase S-methyl_trans PF02574.11 ETO07103.1 - 5e-41 140.9 0.1 1.2e-36 126.6 0.1 2.1 2 0 0 2 2 2 2 Homocysteine S-methyltransferase Kelch_1 PF01344.20 ETO07104.1 - 1.5e-05 24.4 5.3 0.014 14.9 0.5 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 ETO07104.1 - 0.0002 21.1 0.5 0.56 10.2 0.2 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO07104.1 - 0.0017 18.4 7.9 0.42 10.8 0.0 4.1 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.10 ETO07104.1 - 0.005 16.5 3.2 2.2 8.2 0.0 3.8 4 0 0 4 4 4 2 Kelch motif TraC_F_IV PF11130.3 ETO07104.1 - 0.09 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer WD40 PF00400.27 ETO07105.1 - 5.4e-13 48.2 2.3 1.9e-12 46.5 0.1 2.1 2 0 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO07105.1 - 0.029 12.4 0.0 0.029 12.4 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DUF2951 PF11166.3 ETO07106.1 - 9.7 6.1 10.0 4.8 7.0 4.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Ldh_1_C PF02866.13 ETO07108.1 - 1.2e-15 57.7 0.0 1.3e-15 57.5 0.0 1.0 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain ABC2_membrane_3 PF12698.2 ETO07109.1 - 0.0016 17.5 3.0 0.002 17.2 2.1 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ecTbetaR2 PF08917.5 ETO07110.1 - 0.013 15.2 0.2 0.017 14.9 0.1 1.2 1 0 0 1 1 1 0 Transforming growth factor beta receptor 2 ectodomain ArsC PF03960.10 ETO07110.1 - 0.064 13.3 0.0 3.5 7.7 0.1 2.1 1 1 1 2 2 2 0 ArsC family TFIIF_alpha PF05793.7 ETO07112.1 - 0.37 9.0 40.0 0.74 8.1 27.7 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4238 PF14022.1 ETO07113.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4238) Clathrin PF00637.15 ETO07113.1 - 0.016 14.8 0.2 0.035 13.7 0.1 1.7 2 0 0 2 2 2 0 Region in Clathrin and VPS GBA2_N PF12215.3 ETO07114.1 - 0.16 11.0 3.8 0.18 10.9 2.6 1.0 1 0 0 1 1 1 0 beta-Glucocerebrosidase 2 N terminal CagX PF03524.10 ETO07115.1 - 0.018 14.3 1.4 0.02 14.2 1.0 1.1 1 0 0 1 1 1 0 Conjugal transfer protein Vfa1 PF08432.5 ETO07115.1 - 1.6 8.7 11.1 1.6 8.7 7.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PPR PF01535.15 ETO07116.1 - 2.2e-11 42.9 5.8 0.0013 18.5 0.3 5.4 5 0 0 5 5 5 3 PPR repeat PPR_3 PF13812.1 ETO07116.1 - 3.6e-07 29.9 0.2 0.17 12.2 0.0 5.4 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 ETO07116.1 - 4.3e-06 26.5 10.6 0.061 13.2 0.2 5.2 4 1 1 5 5 5 4 PPR repeat family Smr PF01713.16 ETO07116.1 - 0.025 14.7 0.0 0.13 12.4 0.0 2.3 2 0 0 2 2 2 0 Smr domain RhoGEF PF00621.15 ETO07116.1 - 0.031 14.1 5.1 0.037 13.9 2.5 1.9 2 0 0 2 2 2 0 RhoGEF domain WD40 PF00400.27 ETO07117.1 - 2.3e-25 87.5 5.6 3.3e-12 45.7 0.1 3.8 2 1 0 2 2 2 2 WD domain, G-beta repeat Pentapeptide_4 PF13599.1 ETO07117.1 - 6.9e-06 25.7 0.0 1.7e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) F-box-like PF12937.2 ETO07117.1 - 0.0017 18.0 0.2 0.0051 16.5 0.1 1.9 1 0 0 1 1 1 1 F-box-like TSA PF03249.8 ETO07117.1 - 0.0027 16.3 3.3 0.0027 16.3 2.3 1.8 2 0 0 2 2 2 1 Type specific antigen F-box PF00646.28 ETO07117.1 - 0.02 14.5 0.2 0.02 14.5 0.1 1.9 2 0 0 2 2 2 0 F-box domain Secretin_N_2 PF07655.8 ETO07117.1 - 1.8 9.0 24.7 6.8 7.1 0.9 2.9 2 0 0 2 2 2 0 Secretin N-terminal domain DUF3492 PF11997.3 ETO07118.1 - 0.1 12.0 1.3 0.14 11.6 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) PH PF00169.24 ETO07119.1 - 0.00076 19.6 2.8 0.24 11.6 0.4 2.4 2 0 0 2 2 2 2 PH domain CheF-arch PF04283.7 ETO07119.1 - 0.0028 16.9 0.7 0.0092 15.2 0.1 1.9 2 0 0 2 2 2 1 Chemotaxis signal transduction system protein F from archaea Herpes_UL42 PF02282.11 ETO07119.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase processivity factor (UL42) Ribosomal_L23eN PF03939.8 ETO07121.1 - 0.092 12.7 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L23, N-terminal domain DUF4120 PF13496.1 ETO07122.1 - 0.55 10.2 2.8 4.1 7.4 0.2 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4120) CSTF2_hinge PF14327.1 ETO07124.1 - 0.0033 17.4 1.0 0.01 15.8 0.7 1.8 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 Cdd1 PF11731.3 ETO07124.1 - 0.0073 16.2 0.3 0.052 13.4 0.1 2.3 2 1 0 2 2 2 1 Pathogenicity locus Pox_RNA_pol PF03293.9 ETO07124.1 - 0.044 13.2 0.1 0.067 12.7 0.1 1.4 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit DUF719 PF05334.8 ETO07125.1 - 0.06 13.3 0.4 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF719) GSHPx PF00255.14 ETO07126.1 - 1.2e-24 85.7 0.0 4.2e-24 83.9 0.0 1.8 1 1 0 1 1 1 1 Glutathione peroxidase DUF217 PF02697.9 ETO07128.1 - 0.093 12.9 0.2 0.42 10.8 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized ACR, COG1753 Transposase_24 PF03004.9 ETO07129.1 - 0.1 12.4 5.0 0.15 11.9 3.5 1.5 1 1 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) Apolipoprotein PF01442.13 ETO07129.1 - 0.11 12.0 9.9 0.12 11.8 0.8 2.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain TMPIT PF07851.8 ETO07129.1 - 0.33 9.9 7.0 0.51 9.3 4.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein XhlA PF10779.4 ETO07129.1 - 0.66 9.9 0.0 0.66 9.9 0.0 3.2 1 1 2 3 3 3 0 Haemolysin XhlA V_ATPase_I PF01496.14 ETO07129.1 - 0.72 7.6 10.4 0.9 7.3 7.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DIT1_PvcA PF05141.7 ETO07129.1 - 0.74 9.0 6.7 0.085 12.1 1.9 1.4 2 0 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein ALMT PF11744.3 ETO07129.1 - 0.85 8.2 5.4 1 7.9 3.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Acyl-CoA_ox_N PF14749.1 ETO07129.1 - 0.99 9.7 6.7 1.9 8.8 3.0 2.2 1 1 1 2 2 2 0 Acyl-coenzyme A oxidase N-terminal Mnd1 PF03962.10 ETO07129.1 - 1.4 8.5 13.6 0.37 10.4 1.8 2.1 1 1 1 2 2 2 0 Mnd1 family PLU-1 PF08429.6 ETO07131.1 - 0.028 13.3 0.2 0.056 12.3 0.0 1.6 2 0 0 2 2 2 0 PLU-1-like protein COQ9 PF08511.6 ETO07131.1 - 0.072 12.6 0.0 0.31 10.5 0.0 2.0 1 1 1 2 2 2 0 COQ9 MutS_IV PF05190.13 ETO07131.1 - 0.12 12.5 5.9 0.086 13.0 1.5 2.6 2 1 0 2 2 2 0 MutS family domain IV adh_short_C2 PF13561.1 ETO07132.1 - 7.1e-25 88.1 0.3 1.5e-24 87.1 0.2 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETO07132.1 - 4.7e-23 81.9 0.0 1.9e-17 63.6 0.0 2.5 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 ETO07132.1 - 3.5e-06 26.7 0.0 0.0014 18.3 0.0 2.4 2 0 0 2 2 2 2 KR domain DUF2722 PF10846.3 ETO07132.1 - 0.007 15.4 11.6 0.007 15.4 8.1 2.5 2 1 0 2 2 1 1 Protein of unknown function (DUF2722) Mitofilin PF09731.4 ETO07132.1 - 0.26 9.8 33.9 0.66 8.5 8.3 2.0 2 0 0 2 2 2 0 Mitochondrial inner membrane protein Utp14 PF04615.8 ETO07132.1 - 0.41 8.7 47.4 0.008 14.4 8.9 2.1 2 0 0 2 2 2 0 Utp14 protein DUF262 PF03235.9 ETO07132.1 - 0.96 9.3 15.4 0.024 14.6 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF262 Nop14 PF04147.7 ETO07132.1 - 1.6 6.5 45.0 0.15 9.9 11.9 2.1 2 0 0 2 2 2 0 Nop14-like family Tyrosinase PF00264.15 ETO07132.1 - 3.1 7.8 7.2 6.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Common central domain of tyrosinase SAPS PF04499.10 ETO07132.1 - 3.3 6.2 25.0 0.27 9.8 5.6 2.2 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein PLRV_ORF5 PF01690.12 ETO07132.1 - 6.9 5.6 28.2 3.7 6.5 6.4 2.1 2 0 0 2 2 2 0 Potato leaf roll virus readthrough protein DUF2757 PF10955.3 ETO07133.1 - 0.041 14.0 0.4 0.11 12.7 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) Cep57_MT_bd PF06657.8 ETO07133.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 M16C_assoc PF08367.6 ETO07133.1 - 0.15 10.9 0.0 0.15 10.9 0.0 2.1 2 0 0 2 2 2 0 Peptidase M16C associated zf-FCS PF06467.9 ETO07133.1 - 0.85 9.3 4.4 2.8 7.6 0.1 3.0 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif DUF572 PF04502.8 ETO07133.1 - 9.4 5.3 8.6 0.21 10.7 0.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) zf-RING_2 PF13639.1 ETO07134.1 - 0.00014 21.5 16.0 0.0036 17.1 1.0 2.9 2 2 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.2 ETO07134.1 - 0.0036 17.3 8.6 0.41 10.7 0.2 2.4 2 0 0 2 2 2 2 RING-H2 zinc finger zf-C3HC4 PF00097.20 ETO07134.1 - 0.022 14.4 1.1 0.022 14.4 0.8 3.1 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Med15_fungi PF05397.7 ETO07134.1 - 0.047 13.6 1.1 0.086 12.8 0.7 1.4 1 0 0 1 1 1 0 Mediator complex subunit 15 zf-UDP PF14569.1 ETO07134.1 - 0.058 13.1 4.3 1.5 8.6 0.1 2.5 2 1 0 2 2 2 0 Zinc-binding RING-finger DUF1399 PF07173.7 ETO07134.1 - 0.096 12.9 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1399) zf-Apc11 PF12861.2 ETO07134.1 - 0.34 10.7 9.6 3 7.7 0.8 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 ETO07134.1 - 0.9 9.3 14.7 6.8 6.5 5.2 3.1 3 1 0 3 3 3 0 zinc-RING finger domain DUF1033 PF06279.6 ETO07135.1 - 0.055 13.2 0.7 0.13 12.1 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1033) PP_kinase_N PF13089.1 ETO07137.1 - 0.041 13.9 3.6 0.067 13.2 2.5 1.3 1 0 0 1 1 1 0 Polyphosphate kinase N-terminal domain vATP-synt_E PF01991.13 ETO07137.1 - 0.054 12.7 5.9 0.068 12.4 4.1 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit DUF874 PF05917.6 ETO07137.1 - 0.1 11.4 10.0 0.13 11.0 6.9 1.1 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) N6_N4_Mtase PF01555.13 ETO07137.1 - 0.16 11.4 5.8 0.18 11.3 4.0 1.1 1 0 0 1 1 1 0 DNA methylase SBF2 PF12335.3 ETO07137.1 - 0.25 10.6 5.8 0.54 9.5 4.0 1.5 1 1 1 2 2 2 0 Myotubularin protein DUF1436 PF07262.6 ETO07138.1 - 0.037 13.5 0.0 0.073 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1436) HATPase_c_5 PF14501.1 ETO07138.1 - 0.79 9.4 3.7 0.38 10.4 0.2 2.0 2 1 0 2 2 2 0 GHKL domain DUF775 PF05603.7 ETO07139.1 - 1.3e-27 96.6 0.0 1.8e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF775) PhnA_Zn_Ribbon PF08274.7 ETO07139.1 - 0.095 12.5 1.2 4.4 7.1 0.1 2.4 2 0 0 2 2 2 0 PhnA Zinc-Ribbon ABC2_membrane PF01061.19 ETO07140.1 - 5.3e-34 117.2 34.2 2.9e-33 114.7 23.7 1.8 1 1 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 ETO07140.1 - 0.00098 18.2 20.9 0.00098 18.2 14.5 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein YiaAB PF05360.9 ETO07140.1 - 0.43 10.1 4.0 0.96 9.0 1.0 2.5 2 0 0 2 2 2 0 yiaA/B two helix domain DUF4083 PF13314.1 ETO07140.1 - 3.4 7.5 7.6 0.59 10.0 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) TPR_12 PF13424.1 ETO07141.1 - 1.3e-69 230.1 15.4 7.3e-17 61.0 0.5 6.0 2 2 2 6 6 6 6 Tetratricopeptide repeat TPR_11 PF13414.1 ETO07141.1 - 3.1e-33 113.2 20.1 2.7e-10 39.7 0.1 5.5 4 1 0 5 5 5 5 TPR repeat TPR_10 PF13374.1 ETO07141.1 - 8.5e-33 111.3 0.0 6.4e-06 25.9 0.0 8.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETO07141.1 - 1.5e-22 77.6 31.8 5.1e-05 22.8 0.9 9.4 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_1 PF00515.23 ETO07141.1 - 4.3e-22 76.7 40.7 5.2e-05 22.6 0.9 9.5 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_7 PF13176.1 ETO07141.1 - 3e-17 60.9 14.2 6.8e-05 22.3 0.0 8.6 9 1 0 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO07141.1 - 4.3e-17 60.5 45.3 0.0015 18.1 0.7 9.5 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 ETO07141.1 - 3.3e-12 46.7 0.2 0.0091 16.6 0.0 6.0 4 1 2 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO07141.1 - 1.6e-09 37.1 8.7 2.1 8.7 0.0 8.8 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO07141.1 - 1.6e-07 31.2 0.0 0.53 11.0 0.0 6.8 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO07141.1 - 0.00043 20.5 3.8 0.79 10.1 0.1 5.4 3 2 5 8 8 8 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO07141.1 - 0.00044 20.3 22.4 0.26 11.4 0.7 6.0 3 2 4 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETO07141.1 - 0.002 18.4 13.6 7.9 7.1 0.0 8.4 9 0 0 9 9 9 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO07141.1 - 0.048 12.9 3.0 32 3.8 0.0 4.9 6 0 0 6 6 6 0 SHNi-TPR TPR_21 PF09976.4 ETO07141.1 - 0.54 10.1 2.6 40 4.1 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 ETO07141.1 - 2.2 8.2 20.8 7.8 6.4 0.1 6.8 7 1 1 8 8 7 0 MIT (microtubule interacting and transport) domain Phage_int_SAM_4 PF13495.1 ETO07141.1 - 2.5 8.4 8.8 7.4 6.9 0.1 4.4 4 1 0 4 4 4 0 Phage integrase, N-terminal SAM-like domain CBF PF03914.12 ETO07143.1 - 4.4e-13 49.0 6.4 3.1e-08 33.2 0.1 4.1 3 1 0 3 3 3 2 CBF/Mak21 family YxiJ PF14176.1 ETO07145.1 - 0.02 14.9 1.0 0.036 14.1 0.7 1.4 1 0 0 1 1 1 0 YxiJ-like protein zf-RING_5 PF14634.1 ETO07147.1 - 0.00014 21.5 1.5 0.00029 20.5 1.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 ETO07147.1 - 0.00014 21.7 0.7 0.0003 20.7 0.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO07147.1 - 0.00057 19.6 0.4 0.0012 18.6 0.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 ETO07147.1 - 0.0012 18.4 1.6 0.0029 17.2 1.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF2722 PF10846.3 ETO07147.1 - 0.0017 17.4 0.5 0.0017 17.4 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) zf-C3HC4_3 PF13920.1 ETO07147.1 - 0.002 17.7 0.3 0.0034 17.0 0.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 ETO07147.1 - 0.0068 16.0 0.3 0.0068 16.0 0.2 2.1 2 1 0 2 2 1 1 RING-type zinc-finger ABC_membrane PF00664.18 ETO07147.1 - 0.0095 15.3 1.6 0.013 14.8 1.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region zf-C3HC4_4 PF15227.1 ETO07147.1 - 0.01 15.6 0.9 0.056 13.3 0.7 2.3 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING YjgP_YjgQ PF03739.9 ETO07147.1 - 0.049 12.3 0.4 0.084 11.5 0.3 1.4 1 1 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF1917 PF08939.5 ETO07147.1 - 0.1 12.3 0.5 0.12 12.0 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) DUF4557 PF15101.1 ETO07147.1 - 0.12 12.2 5.0 0.12 12.2 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) RED_N PF07808.8 ETO07147.1 - 0.23 10.6 4.1 0.22 10.7 2.8 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region DUF2859 PF11072.3 ETO07147.1 - 0.54 9.7 3.7 0.67 9.4 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2859) Suf PF05843.9 ETO07147.1 - 0.65 9.6 9.5 0.72 9.5 6.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med15 PF09606.5 ETO07147.1 - 1.1 7.4 21.9 1 7.4 15.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.3 ETO07147.1 - 1.3 8.3 9.3 1.9 7.8 6.5 1.4 1 0 0 1 1 1 0 Spt20 family zf-DHHC PF01529.15 ETO07147.1 - 1.3 8.4 21.8 3.5 6.9 15.1 1.6 1 1 0 1 1 1 0 DHHC palmitoyltransferase RAB3GAP2_N PF14655.1 ETO07147.1 - 1.7 7.5 6.8 2.2 7.1 4.7 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus FCP1_C PF09309.5 ETO07147.1 - 3.1 7.0 7.4 3.5 6.8 5.1 1.1 1 0 0 1 1 1 0 FCP1, C-terminal PAT1 PF09770.4 ETO07147.1 - 5.1 5.1 16.8 4.9 5.2 11.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TPR_12 PF13424.1 ETO07148.1 - 5.8e-101 330.5 25.3 8.2e-26 89.7 0.4 5.2 2 1 3 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETO07148.1 - 1e-59 195.8 44.4 3.9e-10 38.9 0.7 8.7 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_11 PF13414.1 ETO07148.1 - 1.1e-55 185.1 38.8 5.4e-16 58.0 1.2 5.3 3 1 3 6 6 6 6 TPR repeat TPR_7 PF13176.1 ETO07148.1 - 2.2e-54 176.9 13.9 1.5e-07 30.6 0.1 8.2 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.12 ETO07148.1 - 1.5e-51 168.2 25.4 6.6e-08 31.8 0.2 8.4 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_8 PF13181.1 ETO07148.1 - 3.7e-48 157.7 52.2 1.8e-08 33.5 1.2 8.0 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_10 PF13374.1 ETO07148.1 - 3.8e-44 147.3 0.0 2.7e-06 27.1 0.0 8.4 9 0 0 9 9 8 7 Tetratricopeptide repeat TPR_17 PF13431.1 ETO07148.1 - 6.1e-29 97.7 12.5 0.0035 17.4 0.0 9.7 9 2 0 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.1 ETO07148.1 - 1.4e-23 82.9 0.0 1.4e-06 28.7 0.0 6.4 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 ETO07148.1 - 3.9e-23 79.8 0.0 0.036 14.7 0.0 8.2 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.1 ETO07148.1 - 5.4e-21 73.5 8.4 0.012 16.0 0.0 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.1 ETO07148.1 - 4.2e-13 49.4 7.5 0.00023 21.4 0.3 6.2 2 2 6 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 ETO07148.1 - 4.3e-12 46.0 23.8 7.7e-06 25.9 2.0 5.2 2 2 4 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 ETO07148.1 - 5.6e-12 45.1 32.3 0.076 12.8 0.4 7.7 8 0 0 8 8 7 6 Tetratricopeptide repeat MIT PF04212.13 ETO07148.1 - 3.1e-11 42.9 25.5 0.019 14.8 0.2 6.8 7 0 0 7 7 7 3 MIT (microtubule interacting and transport) domain PPR PF01535.15 ETO07148.1 - 4e-08 32.7 7.6 0.37 10.8 0.1 7.4 7 0 0 7 7 7 1 PPR repeat Sel1 PF08238.7 ETO07148.1 - 4.7e-06 27.0 14.6 3.2 8.5 0.1 7.0 7 0 0 7 7 6 1 Sel1 repeat TPR_9 PF13371.1 ETO07148.1 - 1.8e-05 24.5 0.0 0.019 14.7 0.0 4.0 3 1 2 5 5 5 1 Tetratricopeptide repeat Musclin PF11037.3 ETO07148.1 - 0.00019 21.0 0.0 25 4.5 0.0 5.3 7 0 0 7 7 6 0 Insulin-resistance promoting peptide in skeletal muscle TPR_5 PF12688.2 ETO07148.1 - 0.00056 19.9 0.0 1.5 8.9 0.0 3.9 2 2 1 3 3 3 1 Tetratrico peptide repeat SHNi-TPR PF10516.4 ETO07148.1 - 0.0016 17.6 5.8 2.5 7.4 0.0 5.5 6 0 0 6 6 6 1 SHNi-TPR DUF2225 PF09986.4 ETO07148.1 - 0.0046 16.4 21.0 0.11 11.9 1.8 4.1 1 1 2 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) Mob_Pre PF01076.14 ETO07148.1 - 0.0049 16.5 10.8 0.085 12.4 0.2 3.4 1 1 1 3 3 3 2 Plasmid recombination enzyme RPN7 PF10602.4 ETO07148.1 - 0.014 14.7 18.5 0.6 9.4 0.6 6.0 3 1 3 7 7 7 0 26S proteasome subunit RPN7 Clathrin PF00637.15 ETO07148.1 - 0.038 13.5 25.5 0.53 9.8 1.7 5.2 1 1 6 7 7 7 0 Region in Clathrin and VPS DUF3568 PF12092.3 ETO07148.1 - 0.052 13.2 2.9 17 5.1 0.0 4.8 1 1 3 5 5 5 0 Protein of unknown function (DUF3568) Fis1_TPR_C PF14853.1 ETO07148.1 - 0.51 10.2 22.9 2.6 8.0 0.1 6.5 7 0 0 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat Serinc PF03348.10 ETO07150.1 - 0.0007 18.4 1.7 0.001 17.8 1.2 1.3 1 0 0 1 1 1 1 Serine incorporator (Serinc) SAPS PF04499.10 ETO07150.1 - 0.0018 17.0 1.0 0.0025 16.5 0.7 1.3 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Vfa1 PF08432.5 ETO07150.1 - 0.0031 17.5 20.9 0.005 16.8 14.5 1.3 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Hom_end_hint PF05203.11 ETO07150.1 - 0.0057 16.4 0.7 0.0062 16.2 0.5 1.2 1 0 0 1 1 1 1 Hom_end-associated Hint NPR3 PF03666.8 ETO07150.1 - 0.055 12.0 16.2 0.079 11.4 11.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.7 ETO07150.1 - 0.21 11.4 11.7 0.29 10.9 8.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_11 PF13086.1 ETO07150.1 - 0.22 11.0 9.2 0.32 10.5 6.4 1.3 1 0 0 1 1 1 0 AAA domain CDC45 PF02724.9 ETO07150.1 - 0.23 9.4 11.4 0.28 9.1 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein OmpH PF03938.9 ETO07150.1 - 0.27 11.1 11.0 0.52 10.2 7.6 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF262 PF03235.9 ETO07150.1 - 0.28 11.0 9.1 0.37 10.7 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 Neur_chan_memb PF02932.11 ETO07150.1 - 0.64 9.8 5.8 0.9 9.3 4.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Rtf2 PF04641.7 ETO07150.1 - 1.1 8.4 23.5 2.2 7.4 16.3 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger DUF3513 PF12026.3 ETO07150.1 - 1.7 8.1 11.8 3.2 7.2 8.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) U79_P34 PF03064.11 ETO07150.1 - 3.7 7.0 24.9 6.4 6.2 17.3 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DDHD PF02862.12 ETO07150.1 - 7.2 6.3 11.3 10 5.8 7.9 1.3 1 0 0 1 1 1 0 DDHD domain GAGA_bind PF06217.7 ETO07150.1 - 7.5 6.4 18.9 11 5.9 13.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DDRGK PF09756.4 ETO07150.1 - 8 5.8 33.7 14 5.0 23.4 1.3 1 0 0 1 1 1 0 DDRGK domain WD40 PF00400.27 ETO07151.1 - 1.2e-28 97.8 0.8 7.1e-11 41.5 0.0 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO07151.1 - 0.0046 15.1 0.5 2 6.4 0.0 2.5 1 1 2 3 3 3 2 Nucleoporin Nup120/160 NACHT PF05729.7 ETO07152.1 - 2.4e-10 40.2 0.0 5.2e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO07152.1 - 1e-06 29.0 0.0 4e-06 27.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ETO07152.1 - 2.7e-05 24.3 0.0 7.2e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO07152.1 - 0.00044 21.0 0.1 0.0023 18.7 0.0 2.2 2 1 1 3 3 2 1 AAA domain DUF2075 PF09848.4 ETO07152.1 - 0.0071 15.3 0.3 0.017 14.1 0.0 1.8 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.1 ETO07152.1 - 0.0079 16.5 9.7 0.0079 16.5 6.7 2.4 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.1 ETO07152.1 - 0.03 13.8 0.6 0.54 9.7 0.0 2.8 2 1 1 3 3 3 0 AAA domain AAA_14 PF13173.1 ETO07152.1 - 0.034 14.0 0.6 0.034 14.0 0.4 2.2 2 1 0 2 2 2 0 AAA domain ATP_bind_2 PF03668.10 ETO07152.1 - 0.043 12.8 0.0 0.077 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop ATPase protein family AAA_10 PF12846.2 ETO07152.1 - 0.053 12.9 1.7 6.2 6.1 0.1 2.6 2 1 1 3 3 3 0 AAA-like domain AAA_29 PF13555.1 ETO07152.1 - 0.055 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.1 ETO07152.1 - 0.06 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 ETO07152.1 - 0.081 12.5 0.0 0.25 10.9 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 ETO07152.1 - 0.095 11.5 0.0 0.17 10.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 ETO07152.1 - 0.45 10.8 3.5 1.4 9.2 2.4 2.0 1 1 0 1 1 1 0 ABC transporter DUF164 PF02591.10 ETO07153.1 - 0.087 12.6 0.1 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative zinc ribbon domain Utp14 PF04615.8 ETO07154.1 - 4.5 5.3 80.8 2.3 6.2 26.8 2.2 2 0 0 2 2 2 0 Utp14 protein MPP6 PF10175.4 ETO07155.1 - 0.83 10.0 4.6 1.1 9.6 0.2 2.3 2 1 0 2 2 2 0 M-phase phosphoprotein 6 DUF4045 PF13254.1 ETO07155.1 - 4.2 6.5 7.4 5 6.3 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) TACC PF05010.9 ETO07156.1 - 0.33 10.6 4.1 0.37 10.5 2.9 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) DSPc PF00782.15 ETO07157.1 - 1.1e-07 31.5 0.1 1.1e-07 31.5 0.1 5.2 7 1 0 7 7 7 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 ETO07157.1 - 0.065 13.4 0.0 0.065 13.4 0.0 5.2 4 2 1 5 5 5 0 Tyrosine phosphatase family RVT_1 PF00078.22 ETO07158.1 - 1e-07 31.5 0.1 1.6e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sterile PF03015.14 ETO07158.1 - 0.14 12.4 3.4 4.7 7.5 0.1 2.7 2 0 0 2 2 2 0 Male sterility protein Toprim_2 PF13155.1 ETO07159.1 - 3e-10 40.2 0.0 4.7e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Toprim-like Toprim_4 PF13662.1 ETO07159.1 - 3e-09 36.7 0.0 4.9e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Toprim domain Toprim_3 PF13362.1 ETO07159.1 - 4.9e-07 29.8 0.0 7.9e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Toprim domain Toprim PF01751.17 ETO07159.1 - 0.00014 21.7 0.0 0.00046 20.1 0.0 1.9 1 1 0 1 1 1 1 Toprim domain Rab3-GTPase_cat PF13890.1 ETO07159.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit HAD_2 PF13419.1 ETO07160.1 - 2.3e-17 63.7 0.0 3.2e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ETO07160.1 - 0.011 15.3 0.0 0.048 13.3 0.0 2.0 2 1 0 2 2 2 0 HAD-hyrolase-like ATP-synt_C PF00137.16 ETO07161.1 - 1.9e-25 88.5 22.0 5.5e-18 64.6 9.5 2.9 2 1 1 3 3 3 2 ATP synthase subunit C TCR_zetazeta PF11628.3 ETO07161.1 - 0.25 10.8 4.4 1.2 8.6 0.9 2.6 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain DUF3810 PF12725.2 ETO07161.1 - 2.2 7.0 5.5 3.1 6.6 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) WD40 PF00400.27 ETO07162.1 - 0.00085 19.1 3.0 0.28 11.1 0.5 2.5 2 1 0 2 2 2 2 WD domain, G-beta repeat Myotub-related PF06602.9 ETO07162.1 - 0.016 13.9 0.9 0.018 13.8 0.6 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DUF4337 PF14235.1 ETO07162.1 - 2 8.2 6.0 3.2 7.5 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF1168 PF06658.7 ETO07162.1 - 2.1 7.8 16.8 3.9 6.9 11.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) WD40 PF00400.27 ETO07163.1 - 0.012 15.4 4.7 12 5.9 0.0 4.5 4 0 0 4 4 4 0 WD domain, G-beta repeat Viral_Rep PF02407.11 ETO07163.1 - 0.024 14.6 0.4 0.058 13.4 0.3 1.6 1 0 0 1 1 1 0 Putative viral replication protein VTC PF09359.5 ETO07164.1 - 1.9e-14 53.3 0.4 3.2e-14 52.6 0.3 1.3 1 1 0 1 1 1 1 VTC domain Cwf_Cwc_15 PF04889.7 ETO07165.1 - 0.3 10.7 11.0 0.35 10.5 7.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Tom22 PF04281.8 ETO07165.1 - 3.1 7.3 6.2 2.3 7.7 3.0 1.7 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Myc_N PF01056.13 ETO07165.1 - 6.1 5.9 8.5 8.4 5.4 5.6 1.4 1 1 0 1 1 1 0 Myc amino-terminal region DUF3245 PF11595.3 ETO07165.1 - 6.5 7.0 17.1 1.9 8.7 5.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3245) He_PIG PF05345.7 ETO07166.1 - 0.19 11.7 0.9 0.53 10.3 0.3 1.9 2 0 0 2 2 2 0 Putative Ig domain Mito_carr PF00153.22 ETO07168.1 - 3.3e-09 36.3 0.1 3.2e-05 23.5 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein WD40 PF00400.27 ETO07169.1 - 2.1e-60 198.5 23.5 6.3e-12 44.8 0.1 7.0 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO07169.1 - 1.1e-12 46.9 8.8 0.0027 15.8 0.1 5.5 3 1 2 5 5 5 5 Nucleoporin Nup120/160 DUF2634 PF10934.3 ETO07169.1 - 0.085 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2634) HAD PF12710.2 ETO07169.1 - 1.6 8.8 6.9 8.4e+02 -0.1 4.8 3.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HSP70 PF00012.15 ETO07170.1 - 2e-95 319.9 0.8 3.1e-95 319.3 0.6 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 ETO07170.1 - 3.9e-11 42.1 0.1 3.8e-10 38.8 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 ETO07170.1 - 0.022 13.8 3.2 0.027 13.5 0.3 2.1 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase DUF912 PF06024.7 ETO07170.1 - 0.023 14.7 0.0 0.093 12.7 0.0 2.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ABC2_membrane_3 PF12698.2 ETO07170.1 - 0.027 13.5 0.1 0.04 12.9 0.1 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Adeno_E3_CR2 PF02439.10 ETO07170.1 - 0.064 12.8 0.3 0.064 12.8 0.2 2.3 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Rcd1 PF04078.8 ETO07170.1 - 0.075 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like YajC PF02699.10 ETO07170.1 - 0.18 11.4 1.3 0.54 9.9 0.9 1.8 1 0 0 1 1 1 0 Preprotein translocase subunit EphA2_TM PF14575.1 ETO07170.1 - 0.46 10.9 2.6 1.9 8.9 0.1 2.9 2 2 1 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain FtsA PF14450.1 ETO07170.1 - 7.3 6.4 7.2 4.5 7.1 1.5 2.8 2 1 0 2 2 2 0 Cell division protein FtsA HSP70 PF00012.15 ETO07171.1 - 1.1e-132 443.0 1.2 1.2e-132 442.8 0.8 1.0 1 0 0 1 1 1 1 Hsp70 protein FGGY_C PF02782.11 ETO07171.1 - 0.0045 16.6 0.0 0.014 15.0 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain nsp7 PF08716.5 ETO07172.1 - 0.036 14.4 0.5 0.06 13.7 0.3 1.3 1 0 0 1 1 1 0 nsp7 replicase PI-PLC-X PF00388.14 ETO07172.1 - 0.13 11.6 0.1 0.86 8.9 0.0 1.9 1 1 1 2 2 2 0 Phosphatidylinositol-specific phospholipase C, X domain BRO1 PF03097.13 ETO07173.1 - 3.8e-17 62.0 0.0 4.6e-17 61.8 0.0 1.0 1 0 0 1 1 1 1 BRO1-like domain DUF3090 PF11290.3 ETO07173.1 - 0.13 11.6 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) RVT_1 PF00078.22 ETO07174.1 - 4e-20 72.0 0.0 1.3e-19 70.4 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) IncA PF04156.9 ETO07174.1 - 0.37 10.3 2.4 1.8 8.0 1.6 2.2 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 ETO07174.1 - 0.98 7.1 4.3 1.8 6.2 3.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DNA_primase_S PF01896.14 ETO07175.1 - 0.012 15.3 0.4 0.02 14.6 0.2 1.4 1 1 0 1 1 1 0 Eukaryotic and archaeal DNA primase small subunit WD40 PF00400.27 ETO07176.1 - 6.2e-68 222.4 19.1 4.9e-13 48.4 0.3 6.7 6 1 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO07176.1 - 4.2e-07 29.8 0.3 0.00094 18.9 0.0 3.2 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO07176.1 - 0.0016 16.7 0.1 0.075 11.3 0.0 2.5 1 1 2 3 3 3 2 Cytochrome D1 heme domain PD40 PF07676.7 ETO07176.1 - 0.0088 15.6 8.2 22 4.8 0.0 5.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Tox-PL PF15644.1 ETO07176.1 - 0.032 14.9 0.0 0.74 10.5 0.0 2.7 1 1 0 1 1 1 0 Papain fold toxin 1 Resistin PF06954.6 ETO07176.1 - 0.04 14.1 0.6 16 5.8 0.0 3.5 2 1 1 3 3 3 0 Resistin DUF2527 PF10736.4 ETO07176.1 - 0.045 13.3 6.3 6.2 6.5 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2627) Nucleoporin_N PF08801.6 ETO07176.1 - 0.17 10.6 12.4 0.099 11.3 0.9 3.9 1 1 1 2 2 2 0 Nup133 N terminal like Plant_tran PF04827.9 ETO07177.1 - 0.051 12.9 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Plant transposon protein CAP18_C PF12153.3 ETO07178.1 - 0.051 13.2 5.4 0.14 11.7 3.7 1.9 1 1 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) Peptidase_S49_N PF08496.5 ETO07179.1 - 0.2 11.4 2.2 0.26 11.0 1.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ion_trans PF00520.26 ETO07179.1 - 2.7 7.2 9.7 3.1 7.0 6.2 1.5 1 1 0 1 1 1 0 Ion transport protein Claudin_2 PF13903.1 ETO07180.1 - 0.0047 16.6 0.0 0.007 16.0 0.0 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction FAM183 PF14886.1 ETO07180.1 - 0.022 15.2 0.9 0.094 13.2 0.1 2.1 1 1 1 2 2 2 0 FAM183A and FAM183B related LLC1 PF14945.1 ETO07180.1 - 0.083 13.2 0.1 0.31 11.3 0.0 1.9 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein WD40 PF00400.27 ETO07182.1 - 4.7e-24 83.3 3.2 2.8e-09 36.4 0.1 3.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO07182.1 - 7.4e-05 21.0 0.5 0.12 10.5 0.0 2.8 1 1 2 3 3 3 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO07182.1 - 0.058 13.1 0.7 13 5.5 0.0 2.8 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.27 ETO07183.1 - 6.4e-16 57.5 1.7 8.4e-09 34.9 0.6 3.0 2 1 0 2 2 2 2 WD domain, G-beta repeat FAM60A PF15396.1 ETO07184.1 - 4 7.1 13.8 5.9 6.5 9.6 1.3 1 0 0 1 1 1 0 Protein Family FAM60A ABC_tran PF00005.22 ETO07186.1 - 3.6e-16 59.7 4.8 9e-15 55.1 3.3 2.6 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 ETO07186.1 - 0.00042 20.3 0.3 0.092 12.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 ETO07186.1 - 0.00069 19.0 0.0 0.0021 17.5 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 ETO07186.1 - 0.0075 16.2 0.1 0.3 11.0 0.0 3.1 2 2 0 2 2 2 1 50S ribosome-binding GTPase REV PF00424.13 ETO07186.1 - 0.046 13.6 0.2 0.19 11.6 0.2 2.0 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Zip PF02535.17 ETO07186.1 - 0.58 9.0 1.9 0.88 8.5 1.0 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter DUF4048 PF13257.1 ETO07186.1 - 0.76 9.3 10.3 1.6 8.2 7.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4048) DUF3024 PF11225.3 ETO07186.1 - 0.83 9.5 5.0 0.25 11.2 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3024) Prog_receptor PF02161.10 ETO07186.1 - 0.88 8.3 3.5 1.3 7.8 2.5 1.1 1 0 0 1 1 1 0 Progesterone receptor CENP-B_dimeris PF09026.5 ETO07186.1 - 8.5 6.6 9.3 21 5.4 6.4 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Striatin PF08232.7 ETO07187.1 - 0.005 17.1 9.3 0.0089 16.3 6.4 1.3 1 0 0 1 1 1 1 Striatin family Atg14 PF10186.4 ETO07187.1 - 0.0059 15.5 6.7 0.007 15.3 4.7 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 SlyX PF04102.7 ETO07187.1 - 0.0065 16.8 3.1 0.0067 16.7 0.8 2.0 2 0 0 2 2 2 1 SlyX Rop-like PF05082.8 ETO07187.1 - 0.008 15.6 1.7 0.018 14.4 1.2 1.6 1 0 0 1 1 1 1 Rop-like FlaC_arch PF05377.6 ETO07187.1 - 0.075 12.9 0.6 0.075 12.9 0.4 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF3573 PF12097.3 ETO07187.1 - 0.13 10.8 7.6 0.19 10.3 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) HET PF06985.6 ETO07187.1 - 0.18 11.9 2.7 0.27 11.3 1.7 1.5 1 1 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Fib_alpha PF08702.5 ETO07187.1 - 0.6 10.2 15.6 2.8 8.0 9.0 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Ndc1_Nup PF09531.5 ETO07187.1 - 1.9 6.8 10.5 2.4 6.4 7.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Tropomyosin_1 PF12718.2 ETO07187.1 - 2 8.2 10.0 0.88 9.4 5.0 1.9 2 1 0 2 2 2 0 Tropomyosin like Med9 PF07544.8 ETO07187.1 - 2.2 8.0 7.4 0.33 10.7 0.6 2.7 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Exonuc_VII_L PF02601.10 ETO07187.1 - 3.5 6.7 12.1 4.3 6.4 8.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit RasGEF PF00617.14 ETO07188.1 - 0.0014 18.3 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain APO_RNA-bind PF05634.6 ETO07190.1 - 0.071 12.2 1.3 0.16 11.1 0.1 2.1 1 1 1 2 2 2 0 APO RNA-binding MACPF PF01823.14 ETO07190.1 - 0.59 9.7 8.6 0.032 13.9 0.6 2.1 2 0 0 2 2 2 0 MAC/Perforin domain Plasmodium_Vir PF05795.6 ETO07190.1 - 1 8.4 11.9 0.19 10.9 1.7 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Apis_Csd PF11671.3 ETO07190.1 - 6.4 6.5 10.3 10 5.9 2.1 2.4 2 0 0 2 2 2 0 Complementary sex determiner protein TFIIF_alpha PF05793.7 ETO07191.1 - 8.4e-05 21.1 17.6 8.9e-05 21.0 12.2 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 ETO07191.1 - 0.0014 16.6 24.7 0.0015 16.5 17.1 1.0 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 ETO07191.1 - 0.0045 15.5 21.0 0.0041 15.7 14.5 1.1 1 0 0 1 1 1 1 Daxx Family SDA1 PF05285.7 ETO07191.1 - 0.01 15.1 16.7 0.0089 15.3 11.6 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 ETO07191.1 - 0.063 11.3 17.1 0.058 11.4 11.9 1.0 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 ETO07191.1 - 0.074 12.1 19.6 0.076 12.0 13.6 1.0 1 0 0 1 1 1 0 BUD22 Spore_coat_CotO PF14153.1 ETO07191.1 - 0.078 12.4 9.2 0.074 12.4 6.4 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF2890 PF11081.3 ETO07191.1 - 0.084 12.9 18.5 0.099 12.6 12.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) RRN3 PF05327.6 ETO07191.1 - 0.12 10.4 10.9 0.1 10.6 7.6 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 MDM1 PF15501.1 ETO07191.1 - 0.2 10.5 12.6 0.24 10.3 8.7 1.0 1 0 0 1 1 1 0 Nuclear protein MDM1 Tim54 PF11711.3 ETO07191.1 - 0.26 9.8 13.2 0.29 9.6 9.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Ycf1 PF05758.7 ETO07191.1 - 0.3 8.7 7.7 0.25 9.0 5.3 1.0 1 0 0 1 1 1 0 Ycf1 Lin-8 PF03353.10 ETO07191.1 - 1.1 8.4 14.4 1.2 8.3 10.0 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist YL1 PF05764.8 ETO07191.1 - 1.2 8.7 21.1 1.2 8.7 14.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein SAPS PF04499.10 ETO07191.1 - 2 6.9 7.1 1.7 7.2 5.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CENP-T PF15511.1 ETO07191.1 - 2.2 7.4 23.0 2.4 7.3 16.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Afi1 PF07792.7 ETO07191.1 - 2.5 8.0 7.3 3.6 7.5 5.1 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Vfa1 PF08432.5 ETO07191.1 - 3.5 7.5 14.6 4.5 7.2 10.1 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SMN PF06003.7 ETO07191.1 - 3.5 6.6 12.3 4.2 6.3 8.5 1.0 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DUF4246 PF14033.1 ETO07191.1 - 4.1 5.8 11.1 4.1 5.8 7.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) RNA_polI_A34 PF08208.6 ETO07191.1 - 4.3 6.9 14.4 4.9 6.7 10.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Casc1 PF12366.3 ETO07193.1 - 0.00043 19.8 2.2 0.00052 19.5 1.5 1.0 1 0 0 1 1 1 1 Cancer susceptibility candidate 1 NAD_binding_3 PF03447.11 ETO07193.1 - 0.0075 16.6 0.6 0.0092 16.3 0.4 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF2828 PF11443.3 ETO07193.1 - 0.063 11.4 1.9 0.074 11.2 1.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Glyco_tranf_2_2 PF10111.4 ETO07193.1 - 0.082 11.9 0.4 0.1 11.6 0.3 1.1 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Amnionless PF14828.1 ETO07193.1 - 0.17 10.3 3.4 0.2 10.0 2.4 1.1 1 0 0 1 1 1 0 Amnionless MAS20 PF02064.10 ETO07193.1 - 0.36 10.7 2.5 0.44 10.4 1.8 1.2 1 0 0 1 1 1 0 MAS20 protein import receptor MMR_HSR1 PF01926.18 ETO07194.1 - 1e-15 57.6 0.1 2.9e-13 49.7 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase IncA PF04156.9 ETO07194.1 - 9e-08 31.9 10.5 9e-08 31.9 7.3 2.2 2 1 0 2 2 2 1 IncA protein CENP-T PF15511.1 ETO07194.1 - 3.9e-06 26.3 9.9 3.9e-06 26.3 6.9 2.2 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T FeoB_N PF02421.13 ETO07194.1 - 2e-05 23.9 0.1 5.8e-05 22.4 0.1 1.8 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 ETO07194.1 - 0.0012 18.1 0.0 0.0027 16.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Sporozoite_P67 PF05642.6 ETO07194.1 - 0.13 10.1 19.0 0.036 11.9 10.4 1.9 1 1 1 2 2 2 0 Sporozoite P67 surface antigen MMPL PF03176.10 ETO07194.1 - 0.14 10.8 2.8 0.27 9.9 2.0 1.4 1 0 0 1 1 1 0 MMPL family DUF2890 PF11081.3 ETO07194.1 - 0.37 10.8 31.6 0.14 12.1 14.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) AA_permease_2 PF13520.1 ETO07194.1 - 0.4 9.1 16.4 0.045 12.2 5.5 2.1 2 0 0 2 2 2 0 Amino acid permease Neur_chan_memb PF02932.11 ETO07194.1 - 3.5 7.4 18.7 0.045 13.6 6.2 2.6 2 1 1 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region DUF4191 PF13829.1 ETO07194.1 - 3.9 6.5 9.9 1.4 7.9 3.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Wzy_C PF04932.10 ETO07194.1 - 5.7 6.6 11.8 0.07 12.9 2.2 2.2 3 0 0 3 3 3 0 O-Antigen ligase WD40 PF00400.27 ETO07195.1 - 2e-21 74.9 10.0 1.1e-09 37.8 0.1 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat WD40 PF00400.27 ETO07196.1 - 0.12 12.2 0.3 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 WD domain, G-beta repeat WD40 PF00400.27 ETO07197.1 - 4.1e-46 153.2 17.1 1.8e-11 43.4 0.0 8.8 10 0 0 10 10 10 6 WD domain, G-beta repeat Kelch_1 PF01344.20 ETO07197.1 - 6.2e-07 28.8 1.7 0.00024 20.5 0.0 3.6 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETO07197.1 - 0.00011 21.8 2.5 0.2 11.4 0.3 3.0 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO07197.1 - 0.00017 21.5 4.8 1.4 9.1 0.1 4.2 2 1 1 3 3 3 2 Kelch motif PD40 PF07676.7 ETO07197.1 - 0.00087 18.9 0.2 10 5.8 0.0 4.8 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO07197.1 - 0.0012 18.3 0.0 0.039 13.4 0.0 2.7 2 1 0 2 2 2 1 PQQ-like domain Kelch_2 PF07646.10 ETO07197.1 - 2.8 7.8 10.2 1.5 8.6 0.1 4.4 5 0 0 5 5 5 0 Kelch motif Kelch_1 PF01344.20 ETO07198.1 - 2.1e-06 27.1 3.2 0.00044 19.7 0.1 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETO07198.1 - 9.6e-06 25.2 0.3 0.096 12.4 0.0 2.7 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO07198.1 - 3.9e-05 23.6 7.8 0.41 10.8 0.1 3.6 2 1 1 3 3 3 2 Kelch motif Kelch_2 PF07646.10 ETO07198.1 - 0.98 9.3 6.0 2.1 8.2 0.2 3.6 4 0 0 4 4 4 0 Kelch motif Kelch_5 PF13854.1 ETO07198.1 - 1 9.4 10.1 4.6 7.3 0.1 3.9 4 0 0 4 4 4 0 Kelch motif WD40 PF00400.27 ETO07199.1 - 9.4e-61 199.6 11.0 8.3e-13 47.6 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO07199.1 - 4.4e-09 36.3 0.0 0.0032 17.1 0.0 2.8 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO07199.1 - 1.2e-08 34.4 5.4 2.3 7.9 0.0 7.0 7 0 0 7 7 7 3 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO07199.1 - 2.9e-05 22.4 0.1 0.16 10.0 0.0 3.6 2 2 0 2 2 2 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO07199.1 - 0.00027 20.4 0.1 0.13 11.7 0.0 3.1 3 0 0 3 3 3 1 PQQ-like domain TFIIIC_delta PF12657.2 ETO07199.1 - 0.012 15.3 0.8 1.6 8.4 0.0 2.5 2 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term Coatomer_WDAD PF04053.9 ETO07199.1 - 0.026 13.3 1.2 1.4 7.5 0.1 2.5 2 1 1 3 3 3 0 Coatomer WD associated region Nucleoporin_N PF08801.6 ETO07199.1 - 0.072 11.8 4.5 0.58 8.8 0.9 3.6 1 1 2 3 3 3 0 Nup133 N terminal like Hira PF07569.6 ETO07199.1 - 0.088 12.0 0.0 56 2.8 0.0 4.0 2 1 3 5 5 5 0 TUP1-like enhancer of split Proteasome_A_N PF10584.4 ETO07199.1 - 5 6.5 12.0 20 4.6 0.0 4.6 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature HMG_box PF00505.14 ETO07200.1 - 2.1e-21 75.9 7.0 2.1e-21 75.9 4.8 3.9 3 1 1 4 4 4 2 HMG (high mobility group) box HMG_box_2 PF09011.5 ETO07200.1 - 1.8e-12 47.4 5.6 1.8e-12 47.4 3.9 4.0 4 0 0 4 4 4 2 HMG-box domain DUF2722 PF10846.3 ETO07202.1 - 0.12 11.3 11.0 0.064 12.2 3.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF755 PF05501.6 ETO07202.1 - 0.58 10.2 18.0 0.093 12.7 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF755) TLP-20 PF06088.6 ETO07202.1 - 0.67 9.6 12.5 0.059 13.0 2.6 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Inhibitor_I71 PF12628.2 ETO07202.1 - 0.72 9.4 8.7 0.12 12.0 2.3 2.2 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor RNA_pol_3_Rpc31 PF11705.3 ETO07202.1 - 3.5 7.5 16.6 0.063 13.1 4.6 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 AUX_IAA PF02309.11 ETO07202.1 - 3.7 7.2 11.8 6.2 6.4 4.2 2.2 2 0 0 2 2 2 0 AUX/IAA family Afi1 PF07792.7 ETO07202.1 - 5.1 7.1 14.1 1.9 8.4 0.8 2.4 2 1 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Peptidase_M1 PF01433.15 ETO07203.1 - 0.00051 19.2 0.0 0.00065 18.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 ETO07204.1 - 1.9e-08 33.9 0.1 2.8e-08 33.3 0.1 1.3 1 1 0 1 1 1 1 ERAP1-like C-terminal domain FMO-like PF00743.14 ETO07205.1 - 1.7e-10 39.7 0.3 1.8e-10 39.6 0.2 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like His_Phos_1 PF00300.17 ETO07206.1 - 7.4e-09 35.8 1.0 0.0022 18.1 0.1 3.4 2 1 1 3 3 3 3 Histidine phosphatase superfamily (branch 1) Pox_Ag35 PF03286.9 ETO07206.1 - 1.6 8.2 22.9 0.23 10.9 2.8 3.0 3 0 0 3 3 3 0 Pox virus Ag35 surface protein Cellulose_synt PF03552.9 ETO07206.1 - 2.3 6.4 6.1 0.66 8.2 0.4 2.0 2 0 0 2 2 2 0 Cellulose synthase Pkinase_Tyr PF07714.12 ETO07207.1 - 9.5e-44 149.4 0.0 2.4e-43 148.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 ETO07207.1 - 2.1e-28 99.1 0.0 3.8e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.2 ETO07208.1 - 5.6e-13 48.1 35.3 3.6e-06 26.4 3.8 6.3 2 1 6 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO07208.1 - 9.3e-13 47.7 36.4 2.7e-05 23.8 3.3 4.0 2 1 3 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 ETO07208.1 - 2e-10 39.1 23.1 0.033 14.1 0.2 8.8 10 0 0 10 10 10 5 Leucine Rich Repeat LRR_7 PF13504.1 ETO07208.1 - 0.0073 16.3 12.5 15 6.2 0.2 6.6 6 0 0 6 6 6 1 Leucine rich repeat LRR_6 PF13516.1 ETO07208.1 - 0.73 10.0 23.3 1.7 8.9 0.1 7.0 9 0 0 9 9 9 0 Leucine Rich repeat Epiglycanin_C PF14654.1 ETO07209.1 - 0.057 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Pmp3 PF01679.12 ETO07209.1 - 0.085 12.5 3.1 0.18 11.5 2.1 1.5 1 0 0 1 1 1 0 Proteolipid membrane potential modulator Utp14 PF04615.8 ETO07209.1 - 0.32 9.1 18.7 0.38 8.8 13.0 1.1 1 0 0 1 1 1 0 Utp14 protein DUF775 PF05603.7 ETO07209.1 - 2.4 7.6 11.4 4.3 6.7 7.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF4629 PF15442.1 ETO07209.1 - 9.9 6.2 16.7 17 5.5 11.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) Kelch_4 PF13418.1 ETO07211.1 - 1.2e-06 28.1 2.4 0.0014 18.3 0.0 3.7 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO07211.1 - 1.6e-06 27.5 4.4 7.4e-05 22.2 0.1 4.0 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 ETO07211.1 - 5.7e-06 26.2 6.1 7.5e-05 22.7 0.2 4.4 4 2 2 6 6 6 1 Kelch motif Kelch_5 PF13854.1 ETO07211.1 - 0.00046 20.0 1.8 3.2 7.8 0.2 4.9 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.10 ETO07211.1 - 0.00086 18.9 1.7 0.057 13.2 0.1 3.8 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 ETO07211.1 - 0.0013 18.8 0.1 0.026 14.6 0.0 3.0 3 0 0 3 3 3 1 Galactose oxidase, central domain YflT PF11181.3 ETO07212.1 - 0.046 13.8 0.2 0.099 12.8 0.2 1.6 1 0 0 1 1 1 0 Heat induced stress protein YflT SSP160 PF06933.6 ETO07212.1 - 0.086 10.8 4.5 0.11 10.4 3.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF912 PF06024.7 ETO07213.1 - 0.0012 18.8 2.2 0.0019 18.1 1.5 1.3 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) ABC2_membrane_3 PF12698.2 ETO07213.1 - 0.0029 16.7 0.2 0.0033 16.5 0.1 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF4407 PF14362.1 ETO07213.1 - 0.012 14.6 1.4 0.013 14.4 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NPIP PF06409.6 ETO07213.1 - 0.012 14.3 4.4 0.017 13.8 3.1 1.2 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) Lipase_2 PF01674.13 ETO07213.1 - 0.024 13.9 0.9 0.03 13.6 0.6 1.1 1 0 0 1 1 1 0 Lipase (class 2) DUF2207 PF09972.4 ETO07213.1 - 0.059 11.9 2.6 0.059 11.9 1.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF106 PF01956.11 ETO07213.1 - 0.083 12.4 3.5 0.12 11.8 2.4 1.4 1 1 0 1 1 1 0 Integral membrane protein DUF106 DUF2130 PF09903.4 ETO07213.1 - 0.17 10.6 10.2 0.2 10.3 7.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) Exonuc_VII_L PF02601.10 ETO07213.1 - 0.54 9.4 6.2 0.63 9.1 4.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF342 PF03961.8 ETO07213.1 - 1 7.7 6.2 1.2 7.4 4.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) OmpH PF03938.9 ETO07213.1 - 1.3 8.9 12.3 1.7 8.6 8.5 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) GP41 PF00517.12 ETO07213.1 - 3.8 7.0 8.2 5.1 6.6 1.6 2.1 1 1 1 2 2 2 0 Retroviral envelope protein Fzo_mitofusin PF04799.8 ETO07213.1 - 10 5.4 8.8 5.5 6.3 4.9 1.5 1 1 0 1 1 1 0 fzo-like conserved region DUF2039 PF10217.4 ETO07214.1 - 0.2 11.7 5.0 0.34 10.9 3.5 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) WD40 PF00400.27 ETO07215.1 - 2.6e-146 470.9 40.9 8.1e-11 41.3 0.1 14.2 14 0 0 14 14 14 14 WD domain, G-beta repeat Nup160 PF11715.3 ETO07215.1 - 1.3e-11 43.3 25.0 0.14 10.2 0.0 10.8 2 2 8 10 10 10 7 Nucleoporin Nup120/160 DUF1258 PF06869.7 ETO07215.1 - 6.1e-09 35.3 11.2 1.1 8.3 0.0 7.6 4 3 1 7 7 7 4 Protein of unknown function (DUF1258) PD40 PF07676.7 ETO07215.1 - 7.1e-06 25.5 12.7 16 5.3 0.1 7.5 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Pentapeptide_4 PF13599.1 ETO07215.1 - 9.2e-06 25.3 0.7 3e-05 23.7 0.5 1.9 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETO07215.1 - 3.1e-05 23.1 2.2 6.7e-05 22.0 1.5 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) UvsW PF11637.3 ETO07215.1 - 6.6e-05 22.5 0.0 11 5.7 0.0 6.3 8 0 0 8 8 8 2 ATP-dependant DNA helicase UvsW DUF2690 PF10901.3 ETO07215.1 - 0.00026 20.9 0.4 6.8 6.7 0.0 6.1 3 2 4 7 7 7 1 Protein of unknown function (DUF2690) Pentapeptide_3 PF13576.1 ETO07215.1 - 0.0018 18.0 2.5 0.0024 17.7 0.2 2.5 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) Cytochrom_D1 PF02239.11 ETO07215.1 - 0.0031 15.8 6.6 13 3.9 0.0 5.6 2 1 2 7 7 7 1 Cytochrome D1 heme domain NYD-SP28_assoc PF14775.1 ETO07215.1 - 0.44 10.2 15.9 14 5.4 0.0 8.0 13 0 0 13 13 12 0 Sperm tail C-terminal domain NACHT PF05729.7 ETO07216.1 - 5.5e-09 35.8 0.0 2.3e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 ETO07216.1 - 1.3e-06 28.5 0.1 7.4e-06 26.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 ETO07216.1 - 0.0067 16.6 0.0 0.025 14.7 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETO07216.1 - 0.0073 16.3 0.5 0.12 12.3 0.2 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 ETO07216.1 - 0.02 15.7 0.2 0.22 12.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 ETO07216.1 - 0.035 14.4 0.0 0.035 14.4 0.0 3.2 3 1 0 3 3 3 0 AAA domain ABC_tran PF00005.22 ETO07216.1 - 0.037 14.3 0.6 0.4 10.9 0.0 2.8 2 0 0 2 2 2 0 ABC transporter RGS PF00615.14 ETO07218.1 - 9.4e-08 32.1 1.2 1.5e-07 31.4 0.8 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF3270 PF11674.3 ETO07218.1 - 0.014 15.3 1.1 0.014 15.3 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) Adap_comp_sub PF00928.16 ETO07219.1 - 3.4e-30 105.0 0.1 4.2e-30 104.7 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family TPR_12 PF13424.1 ETO07220.1 - 3.5e-82 270.3 7.1 9.2e-27 92.8 0.3 4.4 2 2 2 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETO07220.1 - 8.3e-48 159.9 22.3 1.4e-15 56.7 1.3 4.4 3 1 1 4 4 4 4 TPR repeat TPR_10 PF13374.1 ETO07220.1 - 1e-47 158.7 0.0 1.1e-08 34.7 0.0 7.3 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETO07220.1 - 6.6e-45 148.9 34.0 1.2e-10 40.4 0.8 7.3 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.1 ETO07220.1 - 4.5e-43 141.6 3.8 1.2e-08 34.0 0.1 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETO07220.1 - 1e-35 118.7 20.4 1.4e-07 30.9 0.3 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETO07220.1 - 1.6e-29 99.4 41.3 5.3e-07 28.9 1.4 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 ETO07220.1 - 4.3e-23 79.5 8.5 0.0027 17.7 0.0 7.9 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 ETO07220.1 - 4.5e-12 45.4 0.0 0.41 11.4 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat PPR PF01535.15 ETO07220.1 - 4.8e-12 44.9 10.3 0.031 14.2 0.0 6.2 6 0 0 6 6 6 4 PPR repeat TPR_16 PF13432.1 ETO07220.1 - 4.8e-11 43.0 0.0 0.00085 19.9 0.0 4.4 3 2 0 3 3 3 2 Tetratricopeptide repeat MIT PF04212.13 ETO07220.1 - 2.3e-10 40.1 13.4 0.35 10.7 0.2 6.3 6 0 0 6 6 6 3 MIT (microtubule interacting and transport) domain SNAP PF14938.1 ETO07220.1 - 1.2e-09 37.7 8.2 0.00037 19.7 1.0 3.6 1 1 3 4 4 4 3 Soluble NSF attachment protein, SNAP Apc3 PF12895.2 ETO07220.1 - 1.2e-07 31.8 17.2 0.0051 16.9 0.9 4.6 1 1 5 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETO07220.1 - 1.8e-07 31.1 0.4 3.9 8.1 0.0 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat RPN7 PF10602.4 ETO07220.1 - 4.2e-05 23.0 16.0 0.071 12.4 0.9 5.9 1 1 4 6 6 6 1 26S proteasome subunit RPN7 SHNi-TPR PF10516.4 ETO07220.1 - 0.0001 21.4 2.4 5.2 6.3 0.0 5.9 7 0 0 7 7 7 0 SHNi-TPR TPR_19 PF14559.1 ETO07220.1 - 0.00017 21.8 1.1 0.99 9.7 0.1 4.8 2 1 3 6 6 6 2 Tetratricopeptide repeat DUF357 PF04010.8 ETO07220.1 - 0.00034 20.2 14.8 1.7 8.4 0.2 5.2 2 1 3 5 5 5 1 Protein of unknown function (DUF357) KH_4 PF13083.1 ETO07220.1 - 0.00057 19.4 0.2 1.3 8.7 0.0 3.9 1 1 3 4 4 4 1 KH domain DUF3568 PF12092.3 ETO07220.1 - 0.00092 18.9 5.9 2.5 7.8 0.0 4.6 2 1 3 5 5 5 1 Protein of unknown function (DUF3568) TPR_3 PF07720.7 ETO07220.1 - 0.0011 18.7 16.9 0.42 10.4 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat Syntaxin_2 PF14523.1 ETO07220.1 - 0.009 16.0 1.0 3.4 7.7 0.0 3.8 2 1 2 4 4 4 1 Syntaxin-like protein TPR_21 PF09976.4 ETO07220.1 - 0.027 14.4 0.4 0.42 10.5 0.0 2.9 2 2 0 2 2 2 0 Tetratricopeptide repeat DUF627 PF04781.7 ETO07220.1 - 0.028 14.0 5.5 7.1 6.2 0.1 4.4 1 1 4 5 5 5 0 Protein of unknown function (DUF627) FATC PF02260.15 ETO07220.1 - 0.037 13.4 0.8 45 3.5 0.0 3.8 4 0 0 4 4 4 0 FATC domain TPR_5 PF12688.2 ETO07220.1 - 0.078 13.0 0.0 8.3 6.4 0.0 3.3 2 2 1 3 3 3 0 Tetratrico peptide repeat Mob_Pre PF01076.14 ETO07220.1 - 0.1 12.2 0.2 0.1 12.2 0.2 3.0 2 1 1 3 3 3 0 Plasmid recombination enzyme DUF386 PF04074.7 ETO07220.1 - 0.18 11.3 10.4 0.78 9.2 2.7 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF386) Sel1 PF08238.7 ETO07220.1 - 0.18 12.5 9.6 10 6.8 0.0 5.5 6 0 0 6 6 6 0 Sel1 repeat Ubiq-assoc PF09145.5 ETO07220.1 - 0.21 11.4 12.5 5.5 6.9 0.4 6.0 3 2 1 4 4 4 0 Ubiquitin-associated Swi5 PF07061.6 ETO07220.1 - 0.33 10.7 11.3 4.2 7.2 0.5 3.9 2 1 1 3 3 3 0 Swi5 bPH_3 PF14470.1 ETO07220.1 - 0.67 10.2 5.1 27 5.1 0.0 3.8 2 2 2 4 4 4 0 Bacterial PH domain SHD1 PF03983.7 ETO07220.1 - 1.1 9.0 3.9 79 3.0 0.0 3.8 4 0 0 4 4 4 0 SLA1 homology domain 1, SHD1 DUF1731 PF08338.6 ETO07221.1 - 0.12 11.8 0.0 0.28 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) RICTOR_N PF14664.1 ETO07222.1 - 0.0049 15.5 0.3 0.0058 15.2 0.2 1.2 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term E7 PF00527.13 ETO07222.1 - 0.02 15.0 0.8 0.035 14.2 0.6 1.5 1 0 0 1 1 1 0 E7 protein, Early protein DUF3300 PF11737.3 ETO07224.1 - 0.062 12.5 0.3 0.12 11.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3300) NUC129 PF08157.6 ETO07224.1 - 0.19 11.6 1.4 0.5 10.3 1.0 1.7 1 1 0 1 1 1 0 NUC129 domain WD40 PF00400.27 ETO07225.1 - 2.2e-61 201.6 22.7 7.6e-11 41.4 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO07225.1 - 1.5e-11 43.1 2.9 0.0079 14.3 0.0 4.9 1 1 4 5 5 5 5 Nucleoporin Nup120/160 EF-hand_1 PF00036.27 ETO07226.1 - 1.1e-09 36.8 3.8 1.5e-05 23.9 0.3 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 ETO07226.1 - 8.1e-08 31.5 3.1 0.0021 17.7 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 ETO07226.1 - 1.8e-07 30.1 3.2 0.0043 16.3 0.3 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 ETO07226.1 - 7.6e-07 29.1 2.6 0.00048 20.2 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 ETO07226.1 - 8.4e-06 25.3 1.9 9e-06 25.2 0.4 1.7 1 1 1 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.4 ETO07226.1 - 0.0045 17.0 1.7 0.0051 16.8 0.6 1.5 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Muted PF14942.1 ETO07226.1 - 0.014 15.3 0.4 0.016 15.0 0.3 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF932 PF06067.6 ETO07226.1 - 0.063 12.5 0.2 0.07 12.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF932) DUF1007 PF06226.8 ETO07226.1 - 0.084 12.6 4.4 1.7 8.3 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1007) HMG_box_2 PF09011.5 ETO07226.1 - 0.11 12.9 1.9 0.15 12.4 1.3 1.2 1 0 0 1 1 1 0 HMG-box domain PABP PF00658.13 ETO07227.1 - 9.4e-27 92.4 0.8 1.7e-26 91.6 0.6 1.5 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain zf-TRAF PF02176.13 ETO07227.1 - 0.00022 21.5 0.8 0.0004 20.7 0.5 1.4 1 0 0 1 1 1 1 TRAF-type zinc finger NUDE_C PF04880.8 ETO07227.1 - 0.019 15.3 0.7 0.036 14.4 0.5 1.5 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DivIC PF04977.10 ETO07227.1 - 0.2 11.1 3.0 0.42 10.1 1.5 2.0 1 1 0 1 1 1 0 Septum formation initiator Herpes_BLRF2 PF05812.7 ETO07227.1 - 0.22 11.3 13.6 0.74 9.6 2.0 3.4 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein DUF972 PF06156.8 ETO07227.1 - 0.74 10.1 13.0 0.033 14.5 2.9 2.9 2 2 1 3 3 3 0 Protein of unknown function (DUF972) HALZ PF02183.13 ETO07227.1 - 1.4 8.7 8.1 0.12 12.1 0.8 2.8 2 1 0 2 2 2 0 Homeobox associated leucine zipper Sod_Cu PF00080.15 ETO07228.1 - 0.0031 17.6 0.1 0.065 13.3 0.1 2.4 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) PT PF04886.7 ETO07228.1 - 0.024 13.9 76.0 1e+02 2.3 0.2 5.4 2 1 1 3 3 3 0 PT repeat DUF4252 PF14060.1 ETO07229.1 - 0.00017 21.1 2.1 0.00037 20.0 1.3 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4252) DUF718 PF05336.8 ETO07229.1 - 0.016 15.0 0.6 0.024 14.4 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF718) eIF2A PF08662.6 ETO07229.1 - 0.022 14.4 0.0 0.054 13.2 0.0 1.6 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Sialidase PF02973.11 ETO07229.1 - 0.059 12.3 0.3 0.11 11.4 0.1 1.5 1 1 0 1 1 1 0 Sialidase, N-terminal domain LAGLIDADG_2 PF03161.8 ETO07229.1 - 0.6 9.9 3.5 17 5.3 2.4 2.1 1 1 0 1 1 1 0 LAGLIDADG DNA endonuclease family FH2 PF02181.18 ETO07230.1 - 5.8e-44 150.4 2.2 6.7e-44 150.2 1.6 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain VWA_2 PF13519.1 ETO07231.1 - 6.7e-18 65.3 0.0 1e-17 64.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 ETO07231.1 - 5.8e-15 55.4 1.9 2.2e-14 53.5 1.3 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 ETO07231.1 - 0.00096 18.3 0.1 0.014 14.5 0.0 2.2 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein zf-SNAP50_C PF12251.3 ETO07231.1 - 0.011 15.1 0.4 0.028 13.7 0.0 1.9 2 0 0 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal vWA-TerF-like PF10138.4 ETO07231.1 - 0.012 15.4 1.4 2.5 7.8 0.1 2.5 2 0 0 2 2 2 0 vWA found in TerF C terminus VWA_3 PF13768.1 ETO07231.1 - 0.012 15.2 0.1 0.14 11.8 0.0 2.4 2 0 0 2 2 2 0 von Willebrand factor type A domain Ssl1 PF04056.9 ETO07233.1 - 8.8e-22 77.6 0.7 3.9e-20 72.2 0.5 2.1 1 1 0 1 1 1 1 Ssl1-like Adap_comp_sub PF00928.16 ETO07233.1 - 5.4e-06 25.7 0.0 1.2e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 Adaptor complexes medium subunit family PI-PLC-X PF00388.14 ETO07234.1 - 0.074 12.4 0.1 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Fra10Ac1 PF09725.4 ETO07235.1 - 0.017 15.2 0.7 0.045 13.8 0.2 1.8 1 1 1 2 2 2 0 Folate-sensitive fragile site protein Fra10Ac1 Peptidase_C14 PF00656.17 ETO07240.1 - 4.2e-12 46.2 0.3 7.6e-12 45.4 0.2 1.4 1 0 0 1 1 1 1 Caspase domain UCH PF00443.24 ETO07240.1 - 0.12 11.4 1.2 0.17 10.9 0.8 1.3 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF3195 PF11424.3 ETO07240.1 - 0.71 10.0 5.5 0.44 10.7 0.5 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF3195) Peptidase_C14 PF00656.17 ETO07241.1 - 3.1e-13 49.9 0.7 5e-13 49.3 0.5 1.2 1 0 0 1 1 1 1 Caspase domain DUF3195 PF11424.3 ETO07241.1 - 0.38 10.9 7.1 0.75 10.0 0.3 3.9 4 1 1 5 5 5 0 Protein of unknown function (DUF3195) PBP1_TM PF14812.1 ETO07243.1 - 2.4 8.5 9.3 8.4 6.7 4.7 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HSP70 PF00012.15 ETO07244.1 - 2.8e-87 293.0 0.0 1.6e-82 277.4 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein FGGY_C PF02782.11 ETO07244.1 - 0.022 14.3 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain PPR_2 PF13041.1 ETO07245.1 - 5.4e-11 42.3 3.1 3.6e-06 26.8 0.2 3.7 3 0 0 3 3 3 2 PPR repeat family PPR PF01535.15 ETO07245.1 - 1.3e-08 34.2 7.3 0.059 13.3 0.0 5.7 5 0 0 5 5 5 2 PPR repeat PPR_3 PF13812.1 ETO07245.1 - 8e-07 28.8 0.2 2.9 8.3 0.0 4.8 4 0 0 4 4 4 3 Pentatricopeptide repeat domain FAT PF02259.18 ETO07245.1 - 0.016 14.1 0.2 0.026 13.5 0.1 1.3 1 0 0 1 1 1 0 FAT domain Nop25 PF09805.4 ETO07246.1 - 0.02 14.9 17.1 0.042 13.9 11.9 1.5 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) SPX PF03105.14 ETO07246.1 - 0.039 13.7 29.0 0.05 13.3 20.1 1.0 1 0 0 1 1 1 0 SPX domain Pox_A_type_inc PF04508.7 ETO07246.1 - 0.29 11.0 6.1 6.6 6.8 0.2 2.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Striatin PF08232.7 ETO07246.1 - 0.3 11.3 13.7 0.45 10.8 9.5 1.3 1 0 0 1 1 1 0 Striatin family DUF1342 PF07072.6 ETO07246.1 - 1.1 8.8 6.1 0.35 10.4 2.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1342) CobT PF06213.7 ETO07246.1 - 4.3 6.3 15.0 5.8 5.9 10.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF3544 PF12064.3 ETO07246.1 - 4.3 7.0 10.7 6 6.6 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3544) YvrJ PF12841.2 ETO07246.1 - 7.8 5.8 8.3 3.2 7.1 0.4 2.3 2 0 0 2 2 2 0 YvrJ protein family DUF4407 PF14362.1 ETO07246.1 - 8.3 5.2 9.0 11 4.8 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SecY PF00344.15 ETO07249.1 - 2.5e-05 23.3 0.2 2.8e-05 23.2 0.1 1.3 1 1 0 1 1 1 1 SecY translocase CAS_CSE1 PF03378.10 ETO07249.1 - 0.14 10.4 0.2 0.14 10.3 0.2 1.1 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus eRF1_2 PF03464.10 ETO07250.1 - 9.3e-24 84.2 0.4 1.7e-23 83.4 0.0 1.5 2 0 0 2 2 2 1 eRF1 domain 2 eRF1_3 PF03465.10 ETO07250.1 - 3.8e-13 49.6 0.0 7.7e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 Ribosomal_L7Ae PF01248.21 ETO07250.1 - 0.0028 17.1 0.0 0.0058 16.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF3388 PF11868.3 ETO07250.1 - 0.014 14.5 0.1 0.027 13.6 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3388) WD40 PF00400.27 ETO07251.1 - 1.1e-25 88.4 7.4 2.2e-10 40.0 0.1 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO07251.1 - 2.3e-05 22.7 0.9 0.0025 16.0 0.2 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO07251.1 - 0.012 14.3 1.6 3 6.4 0.1 2.6 1 1 2 3 3 3 0 Nup133 N terminal like Melibiase PF02065.13 ETO07252.1 - 1.2e-07 30.8 0.1 3.5e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Melibiase TnpB_IS66 PF05717.8 ETO07254.1 - 0.031 13.7 0.0 0.058 12.8 0.0 1.4 1 0 0 1 1 1 0 IS66 Orf2 like protein SNARE PF05739.14 ETO07255.1 - 4.1e-09 35.9 3.8 7e-09 35.2 2.6 1.4 1 0 0 1 1 1 1 SNARE domain DNA_photolyase PF00875.13 ETO07255.1 - 0.00027 20.7 0.1 0.00035 20.3 0.1 1.3 1 0 0 1 1 1 1 DNA photolyase NPV_P10 PF05531.7 ETO07255.1 - 0.16 12.2 1.7 1.8 8.8 1.2 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 ETO07255.1 - 0.21 11.3 6.2 0.094 12.5 1.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) SlyX PF04102.7 ETO07255.1 - 0.53 10.7 5.3 0.2 12.0 0.4 2.3 2 2 0 2 2 2 0 SlyX IncA PF04156.9 ETO07255.1 - 0.58 9.7 10.8 1.6 8.3 7.5 1.7 1 1 0 1 1 1 0 IncA protein DUF1732 PF08340.6 ETO07255.1 - 0.98 9.2 6.1 0.45 10.3 1.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1732) CENP-Q PF13094.1 ETO07255.1 - 1 9.3 8.0 3.6 7.5 5.6 1.8 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF745 PF05335.8 ETO07255.1 - 2.1 7.8 4.3 1.4 8.4 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF745) NACHT PF05729.7 ETO07256.1 - 5.5e-10 39.1 0.0 1.1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO07256.1 - 1.1e-06 29.0 3.5 3.1e-06 27.4 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 ETO07256.1 - 8.8e-05 22.6 0.2 0.00023 21.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO07256.1 - 0.00031 21.5 0.5 0.0015 19.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 ETO07256.1 - 0.00075 19.1 0.0 0.0019 17.8 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 ATP_bind_2 PF03668.10 ETO07256.1 - 0.012 14.7 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 P-loop ATPase protein family DUF258 PF03193.11 ETO07256.1 - 0.013 14.6 0.1 0.024 13.8 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Torsin PF06309.6 ETO07256.1 - 0.015 15.1 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_33 PF13671.1 ETO07256.1 - 0.016 15.1 0.0 0.03 14.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETO07256.1 - 0.016 15.1 0.2 0.32 10.9 0.1 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 ETO07256.1 - 0.016 15.3 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 ETO07256.1 - 0.017 15.3 0.4 0.039 14.2 0.3 1.7 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 ETO07256.1 - 0.019 14.6 0.0 0.059 13.0 0.0 1.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 ETO07256.1 - 0.026 14.0 0.1 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 ETO07256.1 - 0.031 14.4 2.3 0.049 13.8 0.1 2.5 2 1 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.7 ETO07256.1 - 0.035 13.1 0.0 0.054 12.5 0.0 1.4 1 1 0 1 1 1 0 Zeta toxin AAA_30 PF13604.1 ETO07256.1 - 0.051 13.1 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.4 ETO07256.1 - 0.084 11.7 0.3 0.26 10.1 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_25 PF13481.1 ETO07256.1 - 0.1 11.9 0.2 9 5.6 0.0 2.4 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.21 ETO07256.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 ETO07256.1 - 0.14 11.0 2.1 1.4 7.7 1.4 2.1 1 1 0 1 1 1 0 NB-ARC domain FH2 PF02181.18 ETO07257.1 - 1.1e-23 83.7 3.8 1.3e-23 83.5 2.6 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain Cytadhesin_P30 PF07271.6 ETO07257.1 - 0.04 13.1 16.0 0.068 12.4 11.1 1.3 1 0 0 1 1 1 0 Cytadhesin P30/P32 IFT46_B_C PF12317.3 ETO07259.1 - 0.0053 16.1 0.7 0.0081 15.5 0.5 1.3 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal EF-hand_6 PF13405.1 ETO07259.1 - 0.0065 16.2 0.6 0.016 15.0 0.3 1.8 1 1 0 1 1 1 1 EF-hand domain EB1 PF03271.12 ETO07259.1 - 0.13 12.3 0.8 0.76 9.8 0.4 2.3 2 0 0 2 2 2 0 EB1-like C-terminal motif V-SNARE PF05008.10 ETO07259.1 - 0.24 11.5 3.6 0.32 11.1 1.8 1.8 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Spp-24 PF07448.6 ETO07259.1 - 0.39 10.6 2.6 0.79 9.6 0.1 2.0 2 0 0 2 2 2 0 Secreted phosphoprotein 24 (Spp-24) Ras PF00071.17 ETO07260.1 - 1.1e-42 145.2 0.1 2.3e-42 144.1 0.1 1.5 1 1 0 1 1 1 1 Ras family Miro PF08477.8 ETO07260.1 - 8.1e-17 61.8 0.0 1.7e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO07260.1 - 7.8e-08 31.7 0.1 1.3e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETO07260.1 - 0.0019 17.3 0.0 0.0031 16.7 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RNA_helicase PF00910.17 ETO07260.1 - 0.017 15.2 0.3 1.7 8.8 0.2 2.4 1 1 0 1 1 1 0 RNA helicase Septin PF00735.13 ETO07260.1 - 0.017 14.1 0.4 0.031 13.2 0.0 1.5 2 0 0 2 2 2 0 Septin G-alpha PF00503.15 ETO07260.1 - 0.027 13.1 0.3 0.34 9.5 0.0 2.2 3 0 0 3 3 3 0 G-protein alpha subunit MMR_HSR1 PF01926.18 ETO07260.1 - 0.035 14.0 0.5 0.086 12.7 0.3 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.1 ETO07260.1 - 0.036 13.9 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 ETO07260.1 - 0.083 13.0 0.2 0.2 11.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 ETO07260.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Mucin PF01456.12 ETO07261.1 - 0.016 15.0 12.7 0.016 15.0 8.8 1.4 2 0 0 2 2 2 0 Mucin-like glycoprotein TilS PF09179.6 ETO07261.1 - 0.035 14.1 0.1 0.36 10.8 0.0 2.2 2 0 0 2 2 2 0 TilS substrate binding domain DUF3437 PF11919.3 ETO07261.1 - 0.069 12.8 0.3 0.49 10.1 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3437) SSP160 PF06933.6 ETO07261.1 - 0.65 7.9 8.6 0.84 7.5 6.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 ETO07261.1 - 3.9 7.2 13.7 8.5 6.1 9.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Ras PF00071.17 ETO07263.1 - 1.8e-53 180.2 2.2 7.8e-35 119.6 0.0 2.2 2 0 0 2 2 2 2 Ras family Miro PF08477.8 ETO07263.1 - 1.5e-17 64.1 0.1 2.2e-10 41.0 0.1 2.4 2 0 0 2 2 2 2 Miro-like protein Arf PF00025.16 ETO07263.1 - 3.9e-12 45.7 0.3 9.8e-06 24.9 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO07263.1 - 0.0011 18.4 0.2 0.019 14.3 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Arch_ATPase PF01637.13 ETO07263.1 - 0.011 15.5 1.0 0.026 14.2 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase MMR_HSR1 PF01926.18 ETO07263.1 - 0.015 15.2 0.1 0.052 13.5 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.1 ETO07263.1 - 0.028 14.5 0.1 0.094 12.8 0.0 1.9 2 1 0 2 2 2 0 AAA domain eIF-6 PF01912.13 ETO07263.1 - 0.075 12.1 0.5 4.4 6.3 0.0 2.7 3 0 0 3 3 3 0 eIF-6 family CENP-H PF05837.7 ETO07264.1 - 2.6 8.2 8.6 0.43 10.7 3.0 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Mis14 PF08641.7 ETO07264.1 - 3.6 7.6 11.3 2.2 8.3 0.1 2.2 1 1 1 2 2 2 0 Kinetochore protein Mis14 like WD40 PF00400.27 ETO07265.1 - 7.6e-16 57.3 7.1 1e-08 34.6 0.1 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO07265.1 - 0.0065 14.6 0.5 0.014 13.5 0.1 1.7 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Oxidored_q1_N PF00662.15 ETO07265.1 - 0.074 12.6 1.1 0.15 11.6 0.7 1.5 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus DUF3288 PF11691.3 ETO07266.1 - 0.035 13.8 0.2 0.039 13.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3288) T2SG PF08334.6 ETO07266.1 - 0.082 12.6 1.2 0.097 12.4 0.9 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein G Pyrophosphatase PF00719.14 ETO07266.1 - 0.091 12.2 2.1 0.097 12.1 1.5 1.0 1 0 0 1 1 1 0 Inorganic pyrophosphatase RGS PF00615.14 ETO07266.1 - 0.12 12.4 2.4 0.21 11.6 1.7 1.5 1 1 0 1 1 1 0 Regulator of G protein signaling domain DUF45 PF01863.12 ETO07266.1 - 0.12 12.0 2.0 0.14 11.9 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF45 Mistic PF11458.3 ETO07266.1 - 0.7 10.3 4.1 26 5.3 2.9 2.0 1 1 0 1 1 1 0 Membrane-integrating protein Mistic WD40 PF00400.27 ETO07267.1 - 2.5e-55 182.4 21.5 6.6e-11 41.6 0.3 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO07267.1 - 2e-08 32.8 2.8 0.015 13.4 0.1 4.2 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO07267.1 - 2.2 8.6 13.6 6.4 7.1 0.1 5.4 5 2 1 6 6 6 0 Kelch motif AAA_5 PF07728.9 ETO07269.1 - 1.8e-07 30.9 0.0 2.9e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF835 PF05763.7 ETO07269.1 - 0.059 12.9 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF835) AAA_3 PF07726.6 ETO07269.1 - 0.077 12.5 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Hep_59 PF07052.6 ETO07270.1 - 2.5e-06 27.7 0.4 2.5e-06 27.7 0.3 2.5 2 1 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 Menin PF05053.8 ETO07270.1 - 3.4 5.7 5.4 3.8 5.5 3.8 1.1 1 0 0 1 1 1 0 Menin Macoilin PF09726.4 ETO07270.1 - 4.2 5.5 9.8 4.7 5.3 6.8 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF755 PF05501.6 ETO07270.1 - 4.7 7.2 13.2 0.086 12.8 4.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Lin-8 PF03353.10 ETO07271.1 - 0.12 11.6 3.3 0.14 11.4 2.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist ALMT PF11744.3 ETO07271.1 - 0.28 9.8 1.3 0.37 9.3 0.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Mo25 PF08569.6 ETO07272.1 - 0.00037 19.6 3.3 0.00052 19.1 2.3 1.2 1 0 0 1 1 1 1 Mo25-like DUF3447 PF11929.3 ETO07272.1 - 0.033 13.9 0.4 0.093 12.5 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3447) Kelch_1 PF01344.20 ETO07273.1 - 1.2e-20 72.7 2.3 1.9e-06 27.3 0.0 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 ETO07273.1 - 3.2e-17 61.8 6.1 0.00061 19.8 0.0 5.2 3 2 2 5 5 5 4 Kelch motif Kelch_4 PF13418.1 ETO07273.1 - 1.4e-11 43.9 3.6 0.011 15.5 0.0 5.8 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO07273.1 - 1.6e-11 44.0 1.8 0.0011 19.0 0.0 4.2 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO07273.1 - 7.7e-09 34.9 5.6 0.0079 15.9 0.0 5.4 5 1 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 ETO07273.1 - 4.8e-05 23.2 0.0 0.014 15.3 0.0 3.3 4 0 0 4 4 4 1 Kelch motif Rax2 PF12768.2 ETO07273.1 - 0.00016 20.9 1.3 0.09 11.9 0.3 2.3 1 1 1 2 2 2 2 Cortical protein marker for cell polarity Epimerase PF01370.16 ETO07274.1 - 2.8e-39 134.9 0.0 1.3e-38 132.7 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETO07274.1 - 9.8e-11 40.8 0.0 1.2e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 ETO07274.1 - 1.6e-10 40.3 0.0 1e-05 24.6 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 ETO07274.1 - 2e-06 26.9 0.3 0.00027 19.9 0.2 3.0 2 2 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 ETO07274.1 - 0.00047 19.1 0.0 0.00095 18.1 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain NIF3 PF01784.13 ETO07274.1 - 0.0071 15.9 0.0 0.084 12.4 0.0 2.4 3 0 0 3 3 3 1 NIF3 (NGG1p interacting factor 3) adh_short PF00106.20 ETO07274.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_10 PF13460.1 ETO07274.1 - 0.013 15.5 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding KR PF08659.5 ETO07274.1 - 0.058 13.0 0.0 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 KR domain ADP_ribosyl_GH PF03747.9 ETO07275.1 - 1.6e-23 83.9 0.0 2.7e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase IncA PF04156.9 ETO07275.1 - 0.037 13.6 2.3 0.096 12.2 0.2 2.2 2 0 0 2 2 2 0 IncA protein ABA_GPCR PF12430.3 ETO07275.1 - 0.048 12.7 0.2 0.42 9.7 0.0 2.1 2 0 0 2 2 2 0 Abscisic acid G-protein coupled receptor RP-C_C PF11800.3 ETO07275.1 - 0.45 10.1 5.3 0.43 10.2 2.1 1.8 2 0 0 2 2 2 0 Replication protein C C-terminal region CDT1 PF08839.6 ETO07276.1 - 5.7e-14 52.3 7.2 4.7e-12 46.1 5.0 2.3 1 1 0 1 1 1 1 DNA replication factor CDT1 like SDA1 PF05285.7 ETO07276.1 - 0.00024 20.5 2.8 0.00024 20.5 2.0 1.4 2 0 0 2 2 2 1 SDA1 Pox_Ag35 PF03286.9 ETO07276.1 - 0.00049 19.6 4.3 0.00049 19.6 3.0 1.5 2 0 0 2 2 2 1 Pox virus Ag35 surface protein NIF PF03031.13 ETO07277.1 - 2e-29 102.2 0.5 1.7e-21 76.5 0.0 2.1 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Hum_adeno_E3A PF05393.6 ETO07277.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein DUF3069 PF11269.3 ETO07278.1 - 0.079 13.0 2.0 0.23 11.5 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3069) DUF1835 PF08874.5 ETO07279.1 - 0.069 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) RdRP PF05183.7 ETO07280.1 - 2.7e-30 105.6 3.0 1.9e-16 59.8 0.1 2.4 3 0 0 3 3 3 2 RNA dependent RNA polymerase Rad9 PF04139.8 ETO07280.1 - 0.068 12.2 2.1 0.12 11.4 1.4 1.4 1 0 0 1 1 1 0 Rad9 Condensation PF00668.15 ETO07281.1 - 0.0017 17.2 0.0 0.0025 16.6 0.0 1.2 1 0 0 1 1 1 1 Condensation domain DUF1298 PF06974.8 ETO07282.1 - 4e-06 26.7 0.0 0.00051 19.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1298) SAPS PF04499.10 ETO07282.1 - 0.0031 16.2 1.6 0.0037 15.9 1.1 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Sporozoite_P67 PF05642.6 ETO07282.1 - 0.012 13.5 2.3 0.015 13.1 1.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Daxx PF03344.10 ETO07282.1 - 0.26 9.7 20.8 0.34 9.3 14.4 1.1 1 0 0 1 1 1 0 Daxx Family FAM60A PF15396.1 ETO07282.1 - 0.42 10.3 4.1 0.65 9.7 2.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Apt1 PF10351.4 ETO07282.1 - 0.51 9.1 9.3 0.74 8.5 6.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain CENP-T PF15511.1 ETO07282.1 - 0.66 9.1 10.6 0.92 8.6 7.4 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF2956 PF11169.3 ETO07282.1 - 2.4 8.1 5.9 3.2 7.7 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) SDA1 PF05285.7 ETO07282.1 - 3.6 6.7 21.6 5.2 6.2 15.0 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 ETO07282.1 - 3.7 5.3 21.5 4.8 4.9 14.9 1.1 1 0 0 1 1 1 0 Nop14-like family Herpes_LMP2 PF07415.6 ETO07282.1 - 4.1 5.8 4.7 5.3 5.5 3.3 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Menin PF05053.8 ETO07282.1 - 6.9 4.7 8.1 9.4 4.2 5.6 1.1 1 0 0 1 1 1 0 Menin Hid1 PF12722.2 ETO07282.1 - 8 3.9 11.1 10 3.6 7.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PfkB PF00294.19 ETO07283.1 - 1.5e-19 70.3 0.0 8.5e-09 34.9 0.0 3.3 3 0 0 3 3 3 3 pfkB family carbohydrate kinase CRAL_TRIO PF00650.15 ETO07287.1 - 0.07 12.6 4.7 1.8 8.0 0.6 2.8 1 1 1 2 2 2 0 CRAL/TRIO domain DUF3546 PF12066.3 ETO07288.1 - 0.0033 17.3 0.9 0.0033 17.3 0.6 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF3546) Pept_tRNA_hydro PF01195.14 ETO07288.1 - 0.068 12.6 0.0 0.095 12.1 0.0 1.2 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase DUF2726 PF10881.3 ETO07289.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) FA_desaturase PF00487.19 ETO07290.1 - 0.014 14.8 1.2 0.026 13.9 0.5 1.6 2 0 0 2 2 2 0 Fatty acid desaturase PSK_trans_fac PF07704.6 ETO07290.1 - 0.018 15.6 2.9 0.035 14.7 2.0 1.4 1 0 0 1 1 1 0 Rv0623-like transcription factor PBP_sp32 PF07222.7 ETO07290.1 - 0.053 12.6 2.2 0.12 11.4 1.5 1.6 1 0 0 1 1 1 0 Proacrosin binding protein sp32 EF-hand_1 PF00036.27 ETO07290.1 - 0.058 12.7 0.0 0.17 11.2 0.0 1.8 1 0 0 1 1 1 0 EF hand A_deaminase_N PF08451.6 ETO07290.1 - 0.068 13.1 0.1 0.2 11.6 0.1 1.8 1 0 0 1 1 1 0 Adenosine/AMP deaminase N-terminal PRA1 PF03208.14 ETO07290.1 - 0.088 12.1 4.9 0.83 8.9 0.6 2.7 2 1 0 2 2 2 0 PRA1 family protein Glycophorin_A PF01102.13 ETO07290.1 - 0.46 10.2 5.8 12 5.6 0.0 2.4 2 0 0 2 2 2 0 Glycophorin A Tir_receptor_C PF07489.6 ETO07290.1 - 2 8.1 10.2 3.5 7.3 7.1 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus DUF3439 PF11921.3 ETO07291.1 - 0.011 15.4 4.3 0.022 14.5 3.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) FA_desaturase PF00487.19 ETO07291.1 - 0.021 14.3 1.7 0.038 13.4 1.2 1.3 1 0 0 1 1 1 0 Fatty acid desaturase DUF2721 PF11026.3 ETO07291.1 - 0.033 13.8 0.7 0.033 13.8 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Dicty_REP PF05086.7 ETO07292.1 - 0.0013 16.5 3.0 0.0013 16.5 2.1 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Cyt-b5 PF00173.23 ETO07294.1 - 1.6e-09 37.4 0.0 5.5e-09 35.6 0.0 1.9 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 ETO07294.1 - 6.6e-08 32.3 2.0 6.6e-08 32.3 1.4 1.7 2 0 0 2 2 2 1 Fatty acid desaturase HdeA PF06411.6 ETO07295.1 - 0.094 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 HdeA/HdeB family TTL PF03133.10 ETO07296.1 - 4.9e-23 81.4 2.1 5.4e-19 68.2 0.5 2.1 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 ETO07296.1 - 0.00043 19.1 0.0 0.0054 15.5 0.0 2.1 2 0 0 2 2 2 1 YheC/D like ATP-grasp EnY2 PF10163.4 ETO07296.1 - 0.015 15.1 1.0 0.029 14.2 0.0 1.9 3 0 0 3 3 3 0 Transcription factor e(y)2 Abhydrolase_2 PF02230.11 ETO07297.1 - 1.9e-26 92.8 0.3 2.9e-22 79.1 0.1 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 ETO07297.1 - 1e-07 31.8 0.0 1.7e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 ETO07297.1 - 1.7e-05 24.1 0.0 2.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.15 ETO07297.1 - 0.00072 19.0 0.0 0.00091 18.7 0.0 1.3 1 0 0 1 1 1 1 Putative esterase AXE1 PF05448.7 ETO07297.1 - 0.0014 17.1 0.0 0.0027 16.2 0.0 1.4 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) FSH1 PF03959.8 ETO07297.1 - 0.0017 17.8 1.1 0.0029 17.0 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 ETO07297.1 - 0.0043 16.2 0.1 1.1 8.4 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 ETO07297.1 - 0.005 16.7 0.0 0.029 14.2 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF3089 PF11288.3 ETO07297.1 - 0.0065 15.6 0.9 0.35 10.0 0.0 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF3089) FANCI_S3 PF14677.1 ETO07297.1 - 0.017 14.5 1.1 0.026 13.9 0.8 1.3 1 0 0 1 1 1 0 FANCI solenoid 3 Abhydrolase_1 PF00561.15 ETO07297.1 - 0.02 14.4 0.0 0.039 13.5 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.13 ETO07297.1 - 0.031 13.5 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 ETO07297.1 - 0.043 13.3 0.0 0.26 10.8 0.0 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold EF_assoc_1 PF08355.7 ETO07297.1 - 0.082 12.2 0.0 0.97 8.7 0.0 2.4 2 1 0 2 2 2 0 EF hand associated SF-assemblin PF06705.6 ETO07297.1 - 0.092 11.8 0.9 3.3 6.7 0.1 2.1 2 0 0 2 2 2 0 SF-assemblin/beta giardin Beach PF02138.13 ETO07298.1 - 2.8e-100 335.2 0.0 5.8e-100 334.1 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 ETO07298.1 - 0.00049 19.9 1.2 0.0031 17.3 0.0 2.8 3 0 0 3 3 3 1 PH domain associated with Beige/BEACH PH PF00169.24 ETO07298.1 - 0.0025 17.9 0.6 0.011 15.9 0.4 2.1 1 0 0 1 1 1 1 PH domain PH_6 PF15406.1 ETO07298.1 - 0.054 13.5 0.1 0.41 10.7 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain DUF2305 PF10230.4 ETO07300.1 - 0.015 14.7 0.1 0.019 14.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) EF-hand_2 PF09068.6 ETO07300.1 - 0.077 13.0 0.4 0.13 12.3 0.2 1.5 1 1 0 1 1 1 0 EF hand ZapA PF05164.8 ETO07300.1 - 0.12 12.3 0.1 17 5.4 0.0 2.8 1 1 1 2 2 2 0 Cell division protein ZapA Kelch_6 PF13964.1 ETO07301.1 - 2.7e-05 24.1 4.3 0.082 13.1 0.1 4.6 4 1 1 5 5 5 2 Kelch motif Kelch_5 PF13854.1 ETO07301.1 - 0.01 15.8 4.4 0.82 9.6 1.1 3.7 3 0 0 3 3 3 0 Kelch motif Kelch_3 PF13415.1 ETO07301.1 - 0.014 15.5 0.1 0.014 15.5 0.1 3.2 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO07301.1 - 0.046 13.2 0.5 0.046 13.2 0.4 4.4 5 2 0 5 5 5 0 Kelch motif Kelch_2 PF07646.10 ETO07301.1 - 0.19 11.5 0.9 2 8.3 0.0 3.2 3 0 0 3 3 3 0 Kelch motif Nucleoplasmin PF03066.10 ETO07302.1 - 4.5 6.7 11.6 8.9 5.8 8.1 1.5 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 ETO07302.1 - 4.6 7.5 9.8 9.5 6.5 6.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain BSP_II PF05432.6 ETO07302.1 - 6.8 5.8 13.3 10 5.2 9.3 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DivIC PF04977.10 ETO07303.1 - 0.0037 16.7 4.1 0.0037 16.7 2.8 2.9 2 1 0 2 2 2 1 Septum formation initiator DUF3469 PF11952.3 ETO07303.1 - 0.0049 16.5 1.8 0.013 15.1 0.0 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF3469) Phage_GP20 PF06810.6 ETO07303.1 - 0.012 15.0 11.8 0.012 15.0 8.2 2.5 2 1 1 3 3 3 0 Phage minor structural protein GP20 Geminin PF07412.7 ETO07303.1 - 0.022 14.4 3.3 0.022 14.4 2.3 2.9 1 1 1 2 2 2 0 Geminin Phlebovirus_NSM PF07246.6 ETO07303.1 - 0.047 12.8 10.8 0.061 12.4 7.5 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Methyltransf_9 PF08003.6 ETO07303.1 - 0.079 11.6 0.0 0.079 11.6 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1698) DUF4201 PF13870.1 ETO07303.1 - 0.085 12.2 21.2 0.25 10.7 6.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) MCPsignal PF00015.16 ETO07303.1 - 0.14 11.6 2.6 0.19 11.2 1.8 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF869 PF05911.6 ETO07303.1 - 0.22 9.7 19.0 0.027 12.7 3.9 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF869) RP-C PF03428.8 ETO07303.1 - 0.26 10.7 6.3 1.1 8.6 0.8 2.2 1 1 0 2 2 2 0 Replication protein C N-terminal domain FlaC_arch PF05377.6 ETO07303.1 - 0.29 11.0 12.9 0.91 9.4 1.0 2.9 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) Atg14 PF10186.4 ETO07303.1 - 0.65 8.8 24.0 0.24 10.2 7.7 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Prominin PF05478.6 ETO07303.1 - 1 6.8 11.9 1.2 6.5 8.2 1.2 1 0 0 1 1 1 0 Prominin DUF4140 PF13600.1 ETO07303.1 - 1.1 9.7 9.2 0.08 13.4 0.8 2.5 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) ATG16 PF08614.6 ETO07303.1 - 1.3 8.7 24.3 0.27 11.0 7.1 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF641 PF04859.7 ETO07303.1 - 2.5 7.8 13.8 0.11 12.3 3.7 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) FlgN PF05130.7 ETO07303.1 - 5.6 7.2 15.1 2.7 8.2 2.3 2.3 2 0 0 2 2 2 0 FlgN protein DUF4446 PF14584.1 ETO07303.1 - 8 6.2 12.2 0.95 9.2 2.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF4404 PF14357.1 ETO07303.1 - 10 6.6 13.6 1.9 8.9 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DDE_Tnp_4 PF13359.1 ETO07305.1 - 0.072 12.6 1.1 0.63 9.6 0.0 2.1 2 0 0 2 2 2 0 DDE superfamily endonuclease Kinesin PF00225.18 ETO07306.1 - 2.7e-26 92.0 0.6 2.6e-14 52.6 0.0 2.5 2 1 1 3 3 3 2 Kinesin motor domain KcnmB2_inactiv PF09303.5 ETO07306.1 - 0.17 11.6 0.3 0.42 10.4 0.2 1.6 1 0 0 1 1 1 0 KCNMB2, ball and chain domain Toxin_35 PF10530.4 ETO07307.1 - 0.069 13.2 1.5 0.069 13.2 1.1 2.3 2 0 0 2 2 2 0 Toxin with inhibitor cystine knot ICK or Knottin scaffold OAD_beta PF03977.8 ETO07308.1 - 0.14 10.9 0.0 0.15 10.7 0.0 1.0 1 0 0 1 1 1 0 Na+-transporting oxaloacetate decarboxylase beta subunit Cob_adeno_trans PF01923.13 ETO07309.1 - 0.012 15.3 2.5 0.018 14.8 1.8 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Kelch_2 PF07646.10 ETO07310.1 - 8.8e-08 31.6 1.7 0.0022 17.7 0.1 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO07310.1 - 1.4e-07 31.3 10.2 0.00013 21.9 0.1 4.9 4 1 1 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO07310.1 - 3.2e-07 29.7 5.9 0.0017 17.8 0.1 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO07310.1 - 7.1e-06 25.7 0.5 0.0018 17.9 0.0 2.9 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO07310.1 - 7.5e-06 25.7 6.5 0.13 12.2 0.6 4.7 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 ETO07310.1 - 5.2e-05 23.2 0.0 0.0058 16.7 0.0 3.0 2 0 0 2 2 2 1 Galactose oxidase, central domain Peptidase_C14 PF00656.17 ETO07311.1 - 0.00059 19.6 0.1 0.00075 19.2 0.1 1.1 1 0 0 1 1 1 1 Caspase domain Kelch_5 PF13854.1 ETO07312.1 - 0.023 14.6 0.2 0.53 10.3 0.1 2.7 2 0 0 2 2 2 0 Kelch motif WD40 PF00400.27 ETO07313.1 - 1.3e-67 221.4 15.7 3.5e-13 48.8 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO07313.1 - 8.5e-09 35.3 0.0 4.3e-05 23.3 0.0 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO07313.1 - 1.1e-07 30.4 7.5 0.016 13.3 0.4 5.1 1 1 3 4 4 4 4 Nucleoporin Nup120/160 DUF1258 PF06869.7 ETO07313.1 - 0.0001 21.4 1.0 0.02 13.9 0.0 3.2 1 1 3 4 4 4 1 Protein of unknown function (DUF1258) Cytochrom_D1 PF02239.11 ETO07313.1 - 0.00029 19.2 0.4 0.18 10.1 0.1 3.1 2 1 0 3 3 3 1 Cytochrome D1 heme domain DUF2218 PF09981.4 ETO07313.1 - 0.00077 19.6 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2218) BBS2_Mid PF14783.1 ETO07313.1 - 0.0067 16.1 0.4 0.25 11.1 0.0 3.2 3 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Methyltransf_3 PF01596.12 ETO07313.1 - 0.025 13.6 0.0 0.12 11.4 0.0 2.0 2 0 0 2 2 2 0 O-methyltransferase SusE PF14292.1 ETO07313.1 - 0.038 13.7 0.0 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 SusE outer membrane protein PD40 PF07676.7 ETO07313.1 - 0.1 12.2 7.6 7.8 6.2 0.1 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.2 ETO07313.1 - 0.13 12.0 0.5 0.63 9.7 0.1 2.2 1 1 1 2 2 2 0 Transcription factor IIIC subunit delta N-term CH PF00307.26 ETO07314.1 - 6.3e-10 39.0 1.4 1.5e-09 37.8 0.1 2.1 2 0 0 2 2 2 1 Calponin homology (CH) domain DUF1640 PF07798.6 ETO07314.1 - 0.019 14.9 15.7 0.024 14.6 10.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) BRE1 PF08647.6 ETO07314.1 - 0.026 14.4 15.1 1.4 8.9 3.4 2.6 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase TPR_MLP1_2 PF07926.7 ETO07314.1 - 0.028 14.1 16.3 0.04 13.6 8.3 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.6 ETO07314.1 - 0.053 12.1 12.7 0.072 11.7 8.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CAMSAP_CH PF11971.3 ETO07314.1 - 0.079 12.6 0.1 0.41 10.3 0.0 2.3 2 0 0 2 2 2 0 CAMSAP CH domain THOC7 PF05615.8 ETO07314.1 - 0.089 13.0 11.5 0.21 11.8 7.9 1.9 1 1 0 1 1 1 0 Tho complex subunit 7 DUF4407 PF14362.1 ETO07314.1 - 0.097 11.6 2.4 0.12 11.2 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF342 PF03961.8 ETO07314.1 - 0.15 10.4 6.0 0.2 10.0 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Baculo_PEP_C PF04513.7 ETO07314.1 - 0.16 11.7 1.0 0.75 9.6 0.3 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pox_A_type_inc PF04508.7 ETO07314.1 - 0.43 10.4 12.0 1.4 8.9 0.4 3.6 4 1 0 4 4 2 0 Viral A-type inclusion protein repeat APG6 PF04111.7 ETO07314.1 - 0.75 8.7 14.7 1 8.3 10.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF848 PF05852.6 ETO07314.1 - 0.8 9.5 10.8 1.3 8.8 4.2 2.7 2 1 1 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Syntaxin-6_N PF09177.6 ETO07314.1 - 0.87 10.0 8.6 4.3 7.8 1.7 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF3450 PF11932.3 ETO07314.1 - 1 8.5 12.3 3.3 6.9 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) RP-C_C PF11800.3 ETO07314.1 - 1.8 8.2 7.9 2.4 7.8 5.5 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Adeno_PIX PF03955.9 ETO07314.1 - 2.3 8.7 4.0 4.5 7.8 0.5 2.1 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) CENP-F_leu_zip PF10473.4 ETO07314.1 - 2.9 7.7 20.4 0.71 9.7 11.3 2.1 2 1 1 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.6 ETO07314.1 - 4.1 7.3 7.4 1.3e+02 2.6 4.3 3.0 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF4337 PF14235.1 ETO07314.1 - 4.3 7.1 11.7 9.8 5.9 8.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) Atg14 PF10186.4 ETO07314.1 - 5.4 5.8 14.6 13 4.6 10.1 1.7 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TSC22 PF01166.13 ETO07314.1 - 6.1 6.8 11.9 1.5 8.8 1.3 2.9 2 1 1 3 3 3 0 TSC-22/dip/bun family Phage_GPO PF05929.6 ETO07314.1 - 9 5.4 9.0 0.91 8.7 2.4 1.8 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase WD40 PF00400.27 ETO07315.1 - 1.3e-25 88.3 6.8 5.3e-11 41.9 0.5 4.2 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO07315.1 - 7.1e-05 21.1 0.5 0.11 10.6 0.0 2.7 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO07315.1 - 0.074 11.7 2.7 0.35 9.5 1.9 2.0 1 1 0 1 1 1 0 Nup133 N terminal like Cnd1_N PF12922.2 ETO07316.1 - 0.037 13.6 0.9 0.056 13.0 0.6 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term DUF4131 PF13567.1 ETO07316.1 - 1 8.7 4.5 1.3 8.3 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3043 PF11241.3 ETO07316.1 - 1.5 8.4 7.7 0.66 9.5 4.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3043) WD40 PF00400.27 ETO07317.1 - 5.6e-42 140.1 10.1 1.3e-11 43.8 0.4 5.3 5 1 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO07317.1 - 3.2e-08 32.1 0.6 0.026 12.6 0.0 3.9 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO07317.1 - 8.5e-05 21.4 7.5 0.017 13.8 2.2 2.6 1 1 2 3 3 3 2 Nup133 N terminal like RP-C_C PF11800.3 ETO07318.1 - 0.14 11.7 0.1 0.18 11.5 0.1 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region WD40 PF00400.27 ETO07319.1 - 4e-21 74.0 5.6 2.7e-10 39.7 0.3 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO07319.1 - 5.3e-06 24.8 1.2 3e-05 22.3 0.2 1.9 1 1 0 2 2 2 1 Nucleoporin Nup120/160 DUF972 PF06156.8 ETO07319.1 - 0.0079 16.5 6.2 0.015 15.5 3.6 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF972) Tektin PF03148.9 ETO07319.1 - 0.011 14.3 1.8 0.011 14.3 1.2 1.4 1 1 0 1 1 1 0 Tektin family Laminin_II PF06009.7 ETO07319.1 - 0.092 12.5 6.2 0.14 11.8 4.3 1.3 1 0 0 1 1 1 0 Laminin Domain II CENP-F_leu_zip PF10473.4 ETO07319.1 - 0.14 12.0 9.3 0.2 11.5 6.4 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.4 ETO07319.1 - 0.54 9.1 7.2 0.74 8.6 5.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 ETO07319.1 - 6.4 6.3 7.3 9.3 5.7 5.1 1.2 1 0 0 1 1 1 0 IncA protein Ribosomal_L29 PF00831.18 ETO07319.1 - 7.5 6.3 7.7 4.2 7.1 0.3 2.4 1 1 1 2 2 2 0 Ribosomal L29 protein WD40 PF00400.27 ETO07320.1 - 9.4e-13 47.5 4.9 1.1e-05 25.0 0.5 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat WD40 PF00400.27 ETO07321.1 - 1.5e-22 78.6 11.8 4.4e-08 32.6 0.1 4.6 4 1 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO07321.1 - 0.0099 14.0 0.6 0.035 12.2 0.0 2.1 2 1 0 2 2 2 1 Nucleoporin Nup120/160 WD40 PF00400.27 ETO07322.1 - 5.1e-60 197.3 23.3 7.6e-12 44.6 0.1 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO07322.1 - 1.2e-11 43.4 2.9 0.19 9.8 0.0 5.3 1 1 4 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO07322.1 - 7.1e-05 21.7 10.2 0.018 13.8 0.9 3.4 1 1 2 3 3 3 2 Nup133 N terminal like N-glycanase_N PF09112.5 ETO07322.1 - 0.051 12.9 2.0 0.085 12.2 0.2 2.2 2 1 1 3 3 3 0 Peptide-N-glycosidase F, N terminal DUF3915 PF13054.1 ETO07322.1 - 0.11 12.4 5.8 0.27 11.1 3.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3915) ABC2_membrane_3 PF12698.2 ETO07323.1 - 0.0019 17.3 1.9 0.0022 17.1 1.3 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF976 PF06162.7 ETO07323.1 - 0.0032 16.9 1.2 0.0043 16.5 0.8 1.2 1 0 0 1 1 1 1 Caenorhabditis elegans protein of unknown function (DUF976) DUF3452 PF11934.3 ETO07323.1 - 0.018 14.3 1.1 0.023 13.9 0.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) ODV-E18 PF10717.4 ETO07323.1 - 0.33 10.4 2.3 0.24 10.8 0.3 1.7 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Sulfatase PF00884.18 ETO07324.1 - 1.7e-49 168.6 4.4 2.4e-49 168.1 3.1 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 ETO07324.1 - 1.1e-06 28.1 2.9 1.8e-05 24.2 2.0 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 ETO07324.1 - 3.2e-05 24.2 0.6 0.00016 21.9 0.4 2.1 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase Clp1 PF06807.9 ETO07325.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Pre-mRNA cleavage complex II protein Clp1 DUF1675 PF07897.6 ETO07327.1 - 7.4 6.3 41.0 9.7 5.9 28.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) WD40 PF00400.27 ETO07328.1 - 5.7e-15 54.5 2.7 6.9e-09 35.2 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat BSD PF03909.12 ETO07330.1 - 2.9e-08 33.3 7.7 4.5e-08 32.7 0.1 2.8 3 0 0 3 3 3 2 BSD domain DUF3238 PF11579.3 ETO07330.1 - 0.038 13.6 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3238) EF-hand_5 PF13202.1 ETO07330.1 - 0.084 12.2 0.1 0.57 9.6 0.1 2.4 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.1 ETO07330.1 - 0.16 12.1 0.6 6.9 6.8 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain pair Alpha_GJ PF03229.8 ETO07330.1 - 10 6.5 17.1 9.9 6.5 1.0 2.3 2 0 0 2 2 2 0 Alphavirus glycoprotein J TTL PF03133.10 ETO07331.1 - 0.0046 15.9 0.0 0.0069 15.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family DUF3995 PF13160.1 ETO07331.1 - 0.042 13.9 0.1 0.076 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) N6-adenineMlase PF10237.4 ETO07332.1 - 0.0046 16.6 1.1 0.0051 16.4 0.7 1.2 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase CENP-Q PF13094.1 ETO07334.1 - 0.6 10.1 5.8 0.091 12.7 1.3 1.7 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit S1FA PF04689.8 ETO07334.1 - 4.2 7.3 6.2 6 6.8 3.4 2.0 1 1 0 1 1 1 0 DNA binding protein S1FA zf-TRAF PF02176.13 ETO07335.1 - 8.5e-06 26.0 1.6 8.5e-06 26.0 1.1 3.0 2 1 1 3 3 3 1 TRAF-type zinc finger zf-C3HC4_3 PF13920.1 ETO07335.1 - 6.1e-05 22.5 8.8 0.00018 21.1 6.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO07335.1 - 0.00016 21.6 10.5 0.0015 18.5 7.3 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.11 ETO07335.1 - 0.0012 18.5 2.0 0.0012 18.5 1.4 1.8 2 0 0 2 2 2 1 Seven in absentia protein family Gin PF10764.4 ETO07335.1 - 0.0031 17.1 6.0 0.0031 17.1 4.1 2.2 2 0 0 2 2 2 1 Inhibitor of sigma-G Gin zf-RING_2 PF13639.1 ETO07335.1 - 0.0071 16.1 7.6 0.021 14.6 5.3 1.9 1 0 0 1 1 1 1 Ring finger domain FAM163 PF15069.1 ETO07335.1 - 0.14 12.7 5.4 0.28 11.7 0.1 2.5 2 0 0 2 2 2 0 FAM163 family zf-RING_5 PF14634.1 ETO07335.1 - 0.94 9.2 13.5 4.1 7.1 9.4 2.2 1 1 0 1 1 1 0 zinc-RING finger domain E6 PF00518.12 ETO07335.1 - 1 9.6 14.3 8.5 6.7 0.1 2.9 2 1 0 2 2 2 0 Early Protein (E6) zf-C3HC4 PF00097.20 ETO07335.1 - 3.1 7.5 11.1 32 4.2 7.7 2.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Di19 PF05605.7 ETO07335.1 - 5.7 7.1 10.5 0.054 13.6 0.8 2.5 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding G-patch_2 PF12656.2 ETO07336.1 - 4.8e-16 58.3 2.4 5.4e-16 58.2 0.0 2.3 2 0 0 2 2 2 1 DExH-box splicing factor binding site G-patch PF01585.18 ETO07336.1 - 8.8e-05 22.2 0.9 8.8e-05 22.2 0.6 2.1 2 0 0 2 2 2 1 G-patch domain KOW PF00467.24 ETO07336.1 - 0.00021 20.8 0.1 0.00091 18.8 0.0 2.1 2 0 0 2 2 2 1 KOW motif Serpin PF00079.15 ETO07339.1 - 3.7e-31 108.5 0.0 5e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF2645 PF10840.3 ETO07339.1 - 0.21 11.7 0.0 0.21 11.7 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2645) CCDC142 PF14923.1 ETO07340.1 - 0.075 11.3 0.0 0.13 10.5 0.0 1.4 1 0 0 1 1 1 0 Coiled-coil protein 142 Pox_A_type_inc PF04508.7 ETO07340.1 - 0.94 9.4 4.4 1.1 9.2 1.6 2.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat WD40 PF00400.27 ETO07341.1 - 4.7e-28 96.0 7.0 5.2e-11 41.9 0.1 4.3 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO07341.1 - 0.00024 19.3 0.2 0.19 9.8 0.0 2.8 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO07341.1 - 0.03 13.0 2.1 0.22 10.2 1.5 2.5 1 1 0 1 1 1 0 Nup133 N terminal like Pex14_N PF04695.8 ETO07342.1 - 0.039 14.0 4.9 3.6 7.6 3.7 2.7 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Neur_chan_memb PF02932.11 ETO07342.1 - 5.4 6.8 15.5 19 5.0 10.6 2.1 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Big_2 PF02368.13 ETO07343.1 - 0.00013 21.8 2.2 0.00051 19.8 0.0 2.7 2 2 0 2 2 2 1 Bacterial Ig-like domain (group 2) DnaB PF00772.16 ETO07346.1 - 0.0034 17.2 0.4 0.014 15.2 0.1 2.1 2 0 0 2 2 2 1 DnaB-like helicase N terminal domain DUF4041 PF13250.1 ETO07346.1 - 0.017 14.6 4.8 0.36 10.4 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4041) Barstar PF01337.13 ETO07346.1 - 0.094 12.5 0.6 1.6 8.6 0.0 2.6 2 1 0 2 2 2 0 Barstar (barnase inhibitor) SPOC PF07744.8 ETO07346.1 - 0.14 12.6 0.4 0.55 10.7 0.1 2.0 2 1 0 2 2 2 0 SPOC domain DUF4485 PF14846.1 ETO07346.1 - 4.2 7.1 7.9 0.35 10.6 1.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4485) NACHT PF05729.7 ETO07347.1 - 6.4e-09 35.6 0.0 7.7e-09 35.4 0.0 1.0 1 0 0 1 1 1 1 NACHT domain Nbs1_C PF08599.5 ETO07347.1 - 0.073 12.9 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 DNA damage repair protein Nbs1 WD40 PF00400.27 ETO07348.1 - 5.4e-67 219.4 9.4 7.6e-14 50.9 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat Kelch_1 PF01344.20 ETO07348.1 - 2e-08 33.6 8.7 1.1e-05 24.8 0.2 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO07348.1 - 8e-07 28.7 1.2 0.0019 17.9 0.1 4.6 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO07348.1 - 3.2e-06 27.0 11.0 0.038 14.1 0.2 5.6 6 1 1 7 7 7 2 Kelch motif Kelch_5 PF13854.1 ETO07348.1 - 3.4e-06 26.8 3.8 0.27 11.2 0.1 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 ETO07348.1 - 5.7e-06 25.8 3.6 0.017 14.8 0.2 4.2 2 1 1 3 3 3 2 Kelch motif Nup160 PF11715.3 ETO07348.1 - 0.00016 20.0 2.0 0.33 9.0 0.0 4.3 1 1 1 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO07348.1 - 0.00016 20.6 6.1 0.31 9.7 0.0 4.3 1 1 2 3 3 3 2 Nup133 N terminal like DUF3601 PF12208.3 ETO07348.1 - 0.00029 20.6 0.0 1.4 8.9 0.0 3.7 2 1 1 3 3 3 1 Domain of unknown function (DUF3601) PQQ_2 PF13360.1 ETO07348.1 - 0.00051 19.5 1.1 0.32 10.3 0.0 2.8 1 1 2 3 3 3 2 PQQ-like domain Kelch_3 PF13415.1 ETO07348.1 - 0.0034 17.5 0.7 0.07 13.3 0.0 3.2 4 0 0 4 4 3 1 Galactose oxidase, central domain PD40 PF07676.7 ETO07348.1 - 0.24 11.0 7.6 60 3.4 0.0 5.9 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat DUF4355 PF14265.1 ETO07348.1 - 0.27 11.1 9.8 0.65 9.9 6.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) PDR_CDR PF06422.7 ETO07350.1 - 0.0074 15.9 3.4 0.0074 15.9 2.4 2.8 3 0 0 3 3 3 1 CDR ABC transporter Sigma70_ner PF04546.8 ETO07350.1 - 0.61 9.6 7.8 1.2 8.7 5.4 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region eIF-3c_N PF05470.7 ETO07350.1 - 3.4 5.6 8.6 5.3 5.0 5.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Nop14 PF04147.7 ETO07350.1 - 3.8 5.2 18.5 6.4 4.5 12.8 1.2 1 0 0 1 1 1 0 Nop14-like family Bd3614-deam PF14439.1 ETO07350.1 - 4.2 7.2 15.0 8.5 6.2 4.7 2.5 2 0 0 2 2 2 0 Bd3614-like deaminase CRA PF06589.6 ETO07353.1 - 0.038 13.3 0.2 0.12 11.6 0.1 1.9 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) DUF2457 PF10446.4 ETO07353.1 - 2.1 6.9 13.9 1.4 7.5 7.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) TPR_12 PF13424.1 ETO07354.1 - 4.4e-87 286.0 25.1 6.8e-20 70.7 0.1 6.2 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETO07354.1 - 1.9e-53 176.0 83.1 4.4e-08 32.3 2.6 11.2 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_11 PF13414.1 ETO07354.1 - 1.7e-46 155.6 70.2 3.8e-11 42.4 3.0 6.6 3 2 3 7 7 7 7 TPR repeat TPR_8 PF13181.1 ETO07354.1 - 2.6e-46 151.9 90.1 2.5e-06 26.8 2.3 10.7 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_10 PF13374.1 ETO07354.1 - 4.8e-46 153.4 0.0 1.7e-05 24.5 0.0 10.3 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.12 ETO07354.1 - 1.4e-45 149.5 59.5 7.9e-06 25.4 0.2 10.8 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_7 PF13176.1 ETO07354.1 - 2.4e-40 133.1 28.4 0.00011 21.7 0.0 10.4 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_16 PF13432.1 ETO07354.1 - 1.1e-20 73.7 0.1 0.036 14.7 0.0 7.2 5 2 1 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 ETO07354.1 - 2.5e-18 64.6 27.6 0.0086 16.1 0.1 10.8 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_14 PF13428.1 ETO07354.1 - 1.5e-15 56.2 0.0 0.59 10.9 0.0 8.8 9 1 1 10 10 10 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO07354.1 - 3.4e-14 52.2 31.2 0.035 14.5 1.3 10.6 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.1 ETO07354.1 - 7.3e-10 39.0 13.4 0.062 13.6 0.0 6.0 3 2 1 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 ETO07354.1 - 1e-08 35.1 47.6 0.0096 16.0 5.4 6.6 1 1 6 7 7 7 6 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 ETO07354.1 - 1.7e-07 31.0 29.8 0.36 10.7 1.1 8.3 8 1 1 9 9 9 4 MIT (microtubule interacting and transport) domain DUF3856 PF12968.2 ETO07354.1 - 0.00011 22.0 4.5 5.5 6.8 0.1 5.3 2 1 1 4 4 4 1 Domain of Unknown Function (DUF3856) DUF2225 PF09986.4 ETO07354.1 - 0.024 14.1 34.5 0.84 9.0 1.0 5.2 1 1 3 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_3 PF07720.7 ETO07354.1 - 0.36 10.6 47.1 0.29 10.9 0.5 8.6 9 0 0 9 9 9 0 Tetratricopeptide repeat RPN7 PF10602.4 ETO07354.1 - 0.63 9.3 30.8 6.9 6.0 0.1 7.1 2 1 5 7 7 7 0 26S proteasome subunit RPN7 Peptidase_C14 PF00656.17 ETO07355.1 - 0.00061 19.5 0.1 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 ETO07355.1 - 0.037 13.8 1.5 0.064 13.1 0.2 1.9 1 1 0 2 2 2 0 Raptor N-terminal CASPase like domain TPR_12 PF13424.1 ETO07356.1 - 4.3e-49 164.3 7.0 5.2e-22 77.5 0.2 3.1 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO07356.1 - 1.5e-39 133.4 28.6 8.7e-15 54.1 1.2 3.6 1 1 3 4 4 4 4 TPR repeat TPR_10 PF13374.1 ETO07356.1 - 3e-26 90.5 0.0 1.6e-06 27.8 0.0 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO07356.1 - 1.9e-24 84.2 29.0 1.8e-10 39.9 0.5 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO07356.1 - 5.2e-24 82.1 30.1 7.2e-10 37.9 1.3 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO07356.1 - 1.2e-21 74.8 21.2 6.4e-08 31.9 0.1 4.7 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO07356.1 - 8e-21 72.1 3.0 1.2e-08 34.0 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO07356.1 - 3.9e-13 48.4 10.3 0.0014 18.6 0.0 5.1 4 2 0 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO07356.1 - 6e-10 38.8 0.0 0.11 13.2 0.0 4.6 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO07356.1 - 4.7e-09 36.6 0.0 0.00096 19.7 0.0 3.9 2 1 2 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO07356.1 - 7.4e-09 35.6 11.2 0.0033 17.5 1.1 3.7 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETO07356.1 - 1.3e-08 34.7 4.7 0.021 15.2 0.1 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_3 PF07720.7 ETO07356.1 - 2.9e-07 30.1 23.3 0.028 14.2 0.2 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO07356.1 - 2e-06 28.0 1.1 0.014 15.6 0.0 3.6 1 1 3 4 4 4 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO07356.1 - 8.5e-06 25.5 11.8 0.57 10.1 0.2 4.3 4 0 0 4 4 4 3 Fis1 C-terminal tetratricopeptide repeat DUF627 PF04781.7 ETO07356.1 - 7.7e-05 22.2 7.8 0.012 15.2 0.1 3.7 1 1 3 4 4 4 1 Protein of unknown function (DUF627) Sel1 PF08238.7 ETO07356.1 - 0.00035 21.0 7.9 0.45 11.2 0.0 4.5 4 0 0 4 4 4 1 Sel1 repeat SHNi-TPR PF10516.4 ETO07356.1 - 0.00066 18.8 0.4 2.4 7.4 0.0 3.5 3 0 0 3 3 3 1 SHNi-TPR MIT PF04212.13 ETO07356.1 - 0.00078 19.2 10.6 0.042 13.7 0.2 4.2 5 0 0 5 5 4 1 MIT (microtubule interacting and transport) domain SNAP PF14938.1 ETO07356.1 - 0.001 18.2 4.0 0.14 11.2 1.0 2.1 1 1 0 2 2 2 2 Soluble NSF attachment protein, SNAP RPN7 PF10602.4 ETO07356.1 - 0.002 17.5 4.6 0.022 14.1 0.9 2.4 1 1 1 2 2 2 1 26S proteasome subunit RPN7 Pep3_Vps18 PF05131.9 ETO07356.1 - 0.0035 16.7 4.1 6.2 6.2 0.0 4.1 4 1 0 4 4 4 0 Pep3/Vps18/deep orange family TPR_9 PF13371.1 ETO07356.1 - 0.0097 15.7 0.0 0.24 11.2 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Mob_Pre PF01076.14 ETO07356.1 - 0.011 15.4 0.1 0.37 10.3 0.1 2.3 2 1 0 2 2 2 0 Plasmid recombination enzyme NARP1 PF12569.3 ETO07356.1 - 0.014 14.1 0.7 1.9 7.1 0.0 2.1 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 PPR PF01535.15 ETO07356.1 - 0.023 14.6 10.7 0.12 12.3 0.1 4.6 5 0 0 5 5 5 0 PPR repeat DUF1268 PF06896.6 ETO07356.1 - 0.042 14.1 0.1 0.096 13.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1268) Clathrin PF00637.15 ETO07356.1 - 0.11 12.1 5.5 1.8 8.1 1.8 3.0 1 1 1 2 2 2 0 Region in Clathrin and VPS HEPN PF05168.9 ETO07356.1 - 0.15 11.9 4.9 0.16 11.8 0.6 2.4 1 1 1 2 2 2 0 HEPN domain PRESAN PF09687.5 ETO07356.1 - 0.5 10.4 11.7 0.43 10.6 5.7 2.3 1 1 2 3 3 3 0 Plasmodium RESA N-terminal ATP-synt_E_2 PF08112.6 ETO07356.1 - 0.66 10.0 7.4 2.6 8.1 0.2 3.3 3 0 0 3 3 3 0 ATP synthase epsilon subunit DUF357 PF04010.8 ETO07356.1 - 3.3 7.4 8.9 1.1 9.0 1.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF357) Prefoldin PF02996.12 ETO07356.1 - 8.7 6.0 9.8 9.6 5.8 0.1 3.8 3 1 1 4 4 4 0 Prefoldin subunit SPO22 PF08631.5 ETO07356.1 - 8.9 5.2 8.6 14 4.6 0.1 3.7 3 2 0 5 5 5 0 Meiosis protein SPO22/ZIP4 like WD40 PF00400.27 ETO07357.1 - 1.4e-36 123.0 25.1 7.5e-09 35.1 0.3 6.6 6 1 1 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO07357.1 - 7.8e-07 27.6 4.3 0.00087 17.5 0.8 3.6 1 1 1 2 2 2 2 Nucleoporin Nup120/160 RVT_1 PF00078.22 ETO07358.1 - 2e-12 46.9 0.2 4.5e-10 39.2 0.1 2.7 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 ETO07358.1 - 0.0013 18.8 0.0 0.0029 17.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HEPN PF05168.9 ETO07358.1 - 0.0059 16.4 0.1 0.019 14.8 0.1 1.8 1 0 0 1 1 1 1 HEPN domain RVT_1 PF00078.22 ETO07359.1 - 0.032 13.5 0.2 0.13 11.5 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) SBF2 PF12335.3 ETO07360.1 - 0.0044 16.3 0.9 0.008 15.5 0.6 1.4 1 0 0 1 1 1 1 Myotubularin protein FSA_C PF10479.4 ETO07361.1 - 0.043 11.8 0.3 0.056 11.5 0.2 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Sigma54_DBD PF04552.8 ETO07361.1 - 0.11 11.9 1.2 0.12 11.9 0.1 1.4 2 0 0 2 2 2 0 Sigma-54, DNA binding domain PDEase_I PF00233.14 ETO07362.1 - 7.8e-30 104.3 9.8 2.1e-23 83.3 1.9 2.9 2 1 1 3 3 3 2 3'5'-cyclic nucleotide phosphodiesterase GAF_3 PF13492.1 ETO07362.1 - 3.9e-16 59.3 0.0 5.4e-08 32.9 0.0 4.1 4 0 0 4 4 4 3 GAF domain GAF PF01590.21 ETO07362.1 - 7.2e-16 58.6 0.2 1.1e-07 32.0 0.1 4.0 3 1 0 3 3 3 3 GAF domain GAF_2 PF13185.1 ETO07362.1 - 3.2e-14 53.6 0.0 4.6e-07 30.4 0.0 4.1 4 0 0 4 4 4 3 GAF domain DUF1777 PF08648.7 ETO07364.1 - 3.2 7.4 97.4 39 3.9 26.8 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 ETO07364.1 - 7 4.9 50.0 0.019 13.4 26.0 2.0 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 SPOUT_MTase PF02590.12 ETO07365.1 - 0.045 13.4 1.8 0.045 13.4 0.8 1.4 1 1 0 1 1 1 0 Predicted SPOUT methyltransferase KMP11 PF03037.11 ETO07366.1 - 0.082 13.5 0.1 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 Kinetoplastid membrane protein 11 DUF1777 PF08648.7 ETO07367.1 - 1.3e-07 31.5 54.0 8.7e-06 25.5 24.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1777) Cwf_Cwc_15 PF04889.7 ETO07368.1 - 0.8 9.3 36.6 0.23 11.1 17.8 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PI3_PI4_kinase PF00454.22 ETO07372.1 - 1.7e-11 44.0 0.1 1.5e-08 34.3 0.0 2.4 2 0 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase Pap_E4 PF02711.9 ETO07373.1 - 0.65 10.8 6.2 0.72 10.7 4.3 1.2 1 0 0 1 1 1 0 E4 protein FAM176 PF14851.1 ETO07373.1 - 0.87 9.2 3.6 1 9.0 2.5 1.1 1 0 0 1 1 1 0 FAM176 family U79_P34 PF03064.11 ETO07373.1 - 0.92 8.9 13.8 1 8.8 9.6 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Hid1 PF12722.2 ETO07373.1 - 7.6 4.0 10.3 8.3 3.9 7.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FLO_LFY PF01698.11 ETO07374.1 - 0.014 14.2 8.2 0.02 13.7 5.7 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Zip PF02535.17 ETO07374.1 - 0.12 11.3 10.8 0.016 14.2 3.7 2.2 1 1 1 2 2 2 0 ZIP Zinc transporter YlaH PF14036.1 ETO07374.1 - 1.7 8.7 7.3 11 6.1 0.1 2.9 3 0 0 3 3 3 0 YlaH-like protein CDC45 PF02724.9 ETO07374.1 - 4.8 5.1 16.9 6.4 4.6 11.7 1.2 1 0 0 1 1 1 0 CDC45-like protein MENTAL PF10457.4 ETO07375.1 - 0.031 13.9 0.2 0.04 13.5 0.2 1.2 1 0 0 1 1 1 0 Cholesterol-capturing domain DUF4097 PF13349.1 ETO07375.1 - 0.038 13.5 3.1 0.25 10.8 2.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4097) Ion_trans PF00520.26 ETO07378.1 - 2.5e-47 160.7 12.8 2.5e-47 160.7 8.9 2.6 3 0 0 3 3 3 2 Ion transport protein PKD_channel PF08016.7 ETO07378.1 - 4.9e-09 35.1 22.4 0.00013 20.5 2.2 3.8 3 1 1 4 4 4 3 Polycystin cation channel NPCC PF08058.6 ETO07378.1 - 0.082 12.7 0.3 0.27 11.0 0.2 1.8 1 0 0 1 1 1 0 Nuclear pore complex component Herpes_LMP1 PF05297.6 ETO07378.1 - 5 5.9 8.3 3 6.6 4.0 1.8 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) Ion_trans PF00520.26 ETO07379.1 - 1.4e-32 112.5 0.5 1.4e-32 112.5 0.4 1.4 2 0 0 2 2 2 1 Ion transport protein DUF2346 PF09803.4 ETO07379.1 - 0.048 13.5 1.1 2.2 8.1 0.2 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2346) Sec62 PF03839.11 ETO07383.1 - 0.018 14.4 10.4 0.023 14.0 7.2 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Tmemb_9 PF05434.6 ETO07383.1 - 0.082 12.6 3.0 0.12 12.0 2.1 1.3 1 0 0 1 1 1 0 TMEM9 Rtf2 PF04641.7 ETO07383.1 - 0.092 11.9 12.3 0.13 11.4 8.5 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger NPR3 PF03666.8 ETO07383.1 - 0.11 11.0 6.4 0.13 10.7 4.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TAF1D PF15333.1 ETO07383.1 - 0.34 10.6 19.0 0.46 10.2 13.2 1.1 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D Pellino PF04710.9 ETO07383.1 - 0.9 8.1 6.6 7.7 5.0 3.2 2.0 2 0 0 2 2 2 0 Pellino Sugar_tr PF00083.19 ETO07383.1 - 1.9 6.9 6.1 1.2 7.6 3.3 1.3 1 1 0 1 1 1 0 Sugar (and other) transporter VanZ PF04892.7 ETO07384.1 - 1.7 8.5 10.3 0.13 12.1 1.3 2.4 1 1 2 3 3 3 0 VanZ like family ATP11 PF06644.6 ETO07386.1 - 0.00087 18.8 4.1 0.0018 17.8 2.8 1.4 1 0 0 1 1 1 1 ATP11 protein SDA1 PF05285.7 ETO07386.1 - 0.0026 17.0 7.9 0.0036 16.6 5.5 1.2 1 0 0 1 1 1 1 SDA1 TRAP_alpha PF03896.11 ETO07386.1 - 0.018 14.0 4.1 0.034 13.1 2.8 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF950 PF06106.6 ETO07386.1 - 0.045 13.8 0.1 0.091 12.8 0.0 1.4 1 0 0 1 1 1 0 Staphylococcus protein of unknown function (DUF950) DUF913 PF06025.7 ETO07386.1 - 0.081 11.6 6.0 0.024 13.4 1.1 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) GAGA_bind PF06217.7 ETO07386.1 - 0.19 11.6 5.9 0.29 11.0 4.1 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family CDC45 PF02724.9 ETO07386.1 - 0.28 9.1 5.7 0.38 8.7 4.0 1.2 1 0 0 1 1 1 0 CDC45-like protein NAD_binding_6 PF08030.7 ETO07387.1 - 6.7e-10 39.0 0.0 6.3e-08 32.6 0.0 2.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 ETO07387.1 - 1.3e-05 25.0 0.0 2.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.19 ETO07387.1 - 0.0087 16.1 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Tic20 PF09685.5 ETO07387.1 - 0.074 13.0 1.9 0.12 12.3 1.3 1.3 1 0 0 1 1 1 0 Tic20-like protein DUF3092 PF11289.3 ETO07387.1 - 0.41 9.8 8.2 0.62 9.2 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3092) Syntaxin-6_N PF09177.6 ETO07388.1 - 0.00017 21.9 14.4 0.33 11.3 0.3 4.3 1 1 3 4 4 4 2 Syntaxin 6, N-terminal ISG65-75 PF11727.3 ETO07388.1 - 0.0019 17.3 2.8 0.0019 17.3 1.9 2.8 2 1 1 3 3 3 1 Invariant surface glycoprotein Atg14 PF10186.4 ETO07388.1 - 0.0041 16.1 7.3 0.0041 16.1 5.0 2.0 1 1 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 Baculo_PEP_C PF04513.7 ETO07388.1 - 0.0072 16.1 10.3 0.2 11.5 0.5 3.8 1 1 2 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.6 ETO07388.1 - 0.011 15.6 13.3 2.3 8.1 0.4 5.0 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF2935 PF11155.3 ETO07388.1 - 0.021 14.8 2.5 0.021 14.8 1.7 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF2935) DUF2254 PF10011.4 ETO07388.1 - 0.035 12.5 0.4 0.12 10.7 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) DNA_repr_REX1B PF14966.1 ETO07388.1 - 0.039 14.3 2.2 0.47 10.8 0.0 3.3 2 1 2 4 4 3 0 DNA repair REX1-B GPW_gp25 PF04965.9 ETO07388.1 - 0.054 13.0 0.1 0.36 10.4 0.0 2.3 2 0 0 2 2 2 0 Gene 25-like lysozyme NAAA-beta PF15508.1 ETO07388.1 - 0.068 13.5 5.1 2 8.8 0.1 3.8 1 1 2 4 4 4 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF668 PF05003.7 ETO07388.1 - 0.19 11.9 1.4 5.3 7.3 0.9 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF668) WXG100 PF06013.7 ETO07388.1 - 0.25 11.3 3.5 15 5.6 0.1 3.8 3 1 0 4 4 3 0 Proteins of 100 residues with WXG Img2 PF05046.9 ETO07388.1 - 0.33 11.1 9.9 1.7 8.9 0.1 3.5 3 1 0 3 3 2 0 Mitochondrial large subunit ribosomal protein (Img2) NPV_P10 PF05531.7 ETO07388.1 - 0.36 11.1 13.0 2.3 8.5 2.6 3.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Halogen_Hydrol PF10112.4 ETO07388.1 - 0.46 9.8 10.9 0.04 13.3 1.7 3.1 3 1 1 4 4 4 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF948 PF06103.6 ETO07388.1 - 0.65 9.8 12.4 2.8 7.8 0.9 4.1 3 1 2 5 5 5 0 Bacterial protein of unknown function (DUF948) HisKA PF00512.20 ETO07388.1 - 0.84 9.6 3.2 11 6.1 0.0 3.3 4 1 0 4 4 4 0 His Kinase A (phospho-acceptor) domain COG5 PF10392.4 ETO07388.1 - 0.87 9.5 12.2 1.2 9.1 0.6 3.5 1 1 2 3 3 3 0 Golgi transport complex subunit 5 DUF4239 PF14023.1 ETO07388.1 - 0.93 8.8 3.5 0.83 8.9 0.4 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF4239) FlxA PF14282.1 ETO07388.1 - 1.4 8.9 12.4 0.99 9.3 0.5 3.2 2 1 0 2 2 2 0 FlxA-like protein Rootletin PF15035.1 ETO07388.1 - 1.7 8.5 10.4 0.058 13.3 1.4 2.3 2 1 1 3 3 2 0 Ciliary rootlet component, centrosome cohesion DUF2730 PF10805.3 ETO07388.1 - 1.7 8.3 6.1 12 5.6 0.6 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) Allexi_40kDa PF05549.6 ETO07388.1 - 3 7.0 11.6 2.1 7.5 0.5 2.9 1 1 2 3 3 3 0 Allexivirus 40kDa protein DUF2779 PF11074.3 ETO07388.1 - 4.4 7.3 6.6 1.9e+02 2.0 4.6 3.0 1 1 0 1 1 1 0 Domain of unknown function(DUF2779) Carbpep_Y_N PF05388.6 ETO07388.1 - 5 7.3 11.4 9.5 6.4 0.1 4.1 2 1 2 4 4 4 0 Carboxypeptidase Y pro-peptide Kinesin PF00225.18 ETO07389.1 - 4.4e-30 104.5 0.0 6.7e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain DUF837 PF05769.6 ETO07389.1 - 0.0044 16.5 1.0 0.007 15.9 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF837) DivIC PF04977.10 ETO07389.1 - 0.01 15.3 2.8 0.018 14.5 1.9 1.4 1 0 0 1 1 1 1 Septum formation initiator Herpes_BLRF2 PF05812.7 ETO07389.1 - 0.012 15.4 0.3 0.032 14.0 0.2 1.7 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein bZIP_2 PF07716.10 ETO07389.1 - 0.028 14.2 8.0 0.074 12.8 5.5 1.8 1 1 0 1 1 1 0 Basic region leucine zipper DUF3573 PF12097.3 ETO07389.1 - 0.036 12.6 0.6 0.049 12.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) bZIP_1 PF00170.16 ETO07389.1 - 0.065 13.1 1.8 0.065 13.1 1.2 1.8 1 1 1 2 2 2 0 bZIP transcription factor EBV-NA3 PF05009.7 ETO07389.1 - 0.072 12.3 0.8 0.099 11.8 0.6 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) RBD-FIP PF09457.5 ETO07389.1 - 0.62 9.9 3.3 1.1 9.1 2.3 1.4 1 0 0 1 1 1 0 FIP domain 5_3_exonuc_N PF02739.11 ETO07390.1 - 0.053 12.8 0.2 0.066 12.5 0.2 1.2 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain Kelch_6 PF13964.1 ETO07392.1 - 7.3e-05 22.7 2.2 0.013 15.6 0.1 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETO07392.1 - 0.019 14.6 0.2 0.57 9.9 0.0 3.1 3 0 0 3 3 3 0 Galactose oxidase, central domain DUF4470 PF14737.1 ETO07392.1 - 0.041 13.6 0.1 2 8.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4470) Fe_hyd_lg_C PF02906.9 ETO07392.1 - 0.055 12.7 0.1 0.11 11.7 0.1 1.4 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Kelch_1 PF01344.20 ETO07392.1 - 0.63 9.6 10.8 3.2 7.3 0.4 4.1 4 0 0 4 4 4 0 Kelch motif WD40 PF00400.27 ETO07393.1 - 4e-49 162.8 2.8 7.4e-12 44.6 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO07393.1 - 7.5e-07 29.0 0.4 0.00078 19.1 0.1 2.8 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO07393.1 - 8.5e-07 27.5 2.2 0.013 13.7 0.1 2.8 2 1 1 3 3 3 3 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO07393.1 - 2e-06 26.8 5.5 0.00014 20.7 0.2 3.2 1 1 3 4 4 4 2 Nup133 N terminal like Nup160 PF11715.3 ETO07393.1 - 0.00013 20.2 0.1 0.23 9.5 0.0 3.7 2 1 2 4 4 4 1 Nucleoporin Nup120/160 PD40 PF07676.7 ETO07393.1 - 0.0014 18.2 1.0 11 5.7 0.0 4.3 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO07393.1 - 0.0026 17.2 0.0 0.0099 15.3 0.0 2.1 1 1 1 2 2 2 1 PQQ-like domain Nbas_N PF15492.1 ETO07393.1 - 0.0031 16.6 3.0 0.56 9.2 0.1 4.2 2 2 4 6 6 6 1 Neuroblastoma-amplified sequence, N terminal DPPIV_N PF00930.16 ETO07393.1 - 0.0056 15.3 0.0 9.5 4.6 0.0 3.2 2 1 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Mid2 PF04478.7 ETO07393.1 - 0.0066 15.8 0.2 0.3 10.4 0.0 2.9 3 0 0 3 3 3 1 Mid2 like cell wall stress sensor DUF1258 PF06869.7 ETO07393.1 - 0.036 13.1 0.1 0.077 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) Rav1p_C PF12234.3 ETO07393.1 - 0.26 9.3 2.4 1.2 7.1 0.1 2.5 2 1 1 3 3 3 0 RAVE protein 1 C terminal WD40 PF00400.27 ETO07394.1 - 2e-153 493.5 58.6 2.3e-13 49.4 0.4 14.9 15 0 0 15 15 15 13 WD domain, G-beta repeat PQQ_2 PF13360.1 ETO07394.1 - 5.9e-11 42.2 3.8 5.6e-06 25.9 0.1 3.3 2 1 1 3 3 3 2 PQQ-like domain NACHT PF05729.7 ETO07394.1 - 3.1e-09 36.7 0.0 6.5e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DUF1652 PF07865.6 ETO07394.1 - 6e-06 25.7 0.2 4.6 6.9 0.0 6.9 7 2 2 9 9 9 1 Protein of unknown function (DUF1652) AAA_18 PF13238.1 ETO07394.1 - 6.3e-06 26.5 0.1 6.3e-06 26.5 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 ETO07394.1 - 0.00053 20.1 0.0 0.0019 18.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO07394.1 - 0.0089 16.8 0.0 0.062 14.1 0.0 2.5 1 0 0 1 1 1 1 AAA domain PD40 PF07676.7 ETO07394.1 - 2.9 7.6 28.1 7 6.4 0.1 8.7 10 0 0 10 10 10 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 ETO07395.1 - 1.7e-74 243.2 16.5 9.6e-15 53.8 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO07395.1 - 7.7e-10 38.8 0.4 0.0017 18.0 0.0 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO07395.1 - 1.7e-09 36.4 6.3 0.0033 15.6 0.6 4.8 1 1 1 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO07395.1 - 9e-05 22.0 0.0 0.011 15.2 0.0 2.8 1 1 0 1 1 1 1 PQQ-like domain Nbas_N PF15492.1 ETO07395.1 - 0.00027 20.1 0.8 1.1 8.2 0.0 4.0 3 1 1 5 5 5 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 ETO07395.1 - 0.00034 20.1 8.2 2.7 7.7 0.1 4.6 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO07395.1 - 0.00038 18.8 0.3 0.0053 15.0 0.0 2.5 2 1 0 2 2 2 1 Cytochrome D1 heme domain NHL PF01436.16 ETO07395.1 - 0.0038 17.1 0.2 3.4 7.7 0.0 2.6 2 0 0 2 2 2 2 NHL repeat DUF1652 PF07865.6 ETO07395.1 - 0.0052 16.3 0.0 1.8 8.1 0.0 3.7 4 1 0 4 4 4 1 Protein of unknown function (DUF1652) Coatomer_WDAD PF04053.9 ETO07395.1 - 0.0064 15.3 2.1 0.018 13.8 0.6 2.2 1 1 1 2 2 2 1 Coatomer WD associated region PQQ PF01011.16 ETO07395.1 - 0.017 14.6 0.0 8.9 6.0 0.0 3.9 5 0 0 5 5 5 0 PQQ enzyme repeat Hira PF07569.6 ETO07395.1 - 0.042 13.0 2.0 7.1 5.7 0.0 4.0 1 1 2 4 4 4 0 TUP1-like enhancer of split YopX PF09643.5 ETO07395.1 - 0.08 12.9 0.1 0.16 11.9 0.1 1.6 1 1 0 1 1 1 0 YopX protein GSDH PF07995.6 ETO07395.1 - 0.12 11.3 0.0 2.4 7.1 0.0 2.7 3 1 0 3 3 3 0 Glucose / Sorbosone dehydrogenase Kelch_6 PF13964.1 ETO07398.1 - 6.7e-07 29.2 3.7 5.4e-06 26.3 0.2 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.20 ETO07398.1 - 3.9e-06 26.2 0.8 3.9e-06 26.2 0.5 2.9 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 ETO07398.1 - 7.1e-05 22.8 0.1 0.001 19.1 0.0 2.5 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO07398.1 - 0.00013 21.7 0.6 0.0037 17.0 0.1 2.7 1 1 1 2 2 2 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO07398.1 - 0.5 10.2 5.0 0.37 10.6 0.7 2.7 3 0 0 3 3 3 0 Kelch motif RVT_1 PF00078.22 ETO07399.1 - 2.8e-10 39.9 0.1 2.5e-05 23.7 0.1 2.8 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Imm15 PF15590.1 ETO07400.1 - 0.048 12.7 0.1 0.1 11.7 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 15 Ank_2 PF12796.2 ETO07401.1 - 1.6e-05 25.1 0.5 0.00028 21.1 0.0 2.9 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO07401.1 - 5.5e-05 23.2 0.3 0.00069 19.7 0.0 3.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO07401.1 - 5.6e-05 23.5 0.2 0.00027 21.3 0.1 2.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) HEAT_2 PF13646.1 ETO07401.1 - 0.00018 21.6 0.0 1.6 9.0 0.0 3.4 3 0 0 3 3 3 2 HEAT repeats Ank_3 PF13606.1 ETO07401.1 - 0.0011 18.9 0.1 0.02 15.1 0.0 3.3 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.25 ETO07401.1 - 0.0034 17.1 0.0 0.02 14.6 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat HEAT_EZ PF13513.1 ETO07401.1 - 0.015 15.7 0.0 3.2 8.3 0.0 3.2 2 1 1 3 3 3 0 HEAT-like repeat DUF2435 PF10363.4 ETO07401.1 - 0.055 13.3 15.2 0.087 12.7 0.1 5.3 5 1 1 6 6 6 0 Protein of unknown function (DUF2435) DUF3944 PF13099.1 ETO07401.1 - 0.13 11.7 0.1 0.13 11.7 0.0 5.0 6 0 0 6 6 6 0 Domain of unknown function (DUF3944) WD40 PF00400.27 ETO07402.1 - 2.7e-15 55.5 1.1 2.5e-06 27.1 0.0 2.8 4 0 0 4 4 4 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO07402.1 - 0.0078 15.0 2.2 0.024 13.3 1.5 1.7 1 1 0 1 1 1 1 Nup133 N terminal like WD40 PF00400.27 ETO07403.1 - 1.2e-25 88.3 5.8 1.1e-10 41.0 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO07403.1 - 1.3e-08 33.5 0.3 0.0018 16.5 0.0 2.0 2 0 0 2 2 2 2 Nucleoporin Nup120/160 DUF1743 PF08489.6 ETO07404.1 - 0.16 11.7 0.0 0.68 9.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1743) DUF1265 PF06887.9 ETO07405.1 - 0.048 13.3 4.4 0.14 11.8 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1265) 2-oxoacid_dh PF00198.18 ETO07406.1 - 6.6e-67 225.1 0.1 5.1e-65 218.9 0.1 2.1 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 ETO07406.1 - 3.3e-17 61.8 1.8 5.1e-17 61.2 1.3 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme DUF4164 PF13747.1 ETO07406.1 - 0.047 13.8 0.5 0.087 12.9 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) GCV_H PF01597.14 ETO07406.1 - 0.047 13.3 0.4 0.092 12.4 0.3 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein Biotin_lipoyl_2 PF13533.1 ETO07406.1 - 0.1 12.2 1.0 0.42 10.3 0.1 2.2 1 1 1 2 2 2 0 Biotin-lipoyl like DUF2397 PF09660.5 ETO07406.1 - 0.22 10.0 2.8 0.32 9.5 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) Med3 PF11593.3 ETO07406.1 - 0.56 9.3 6.7 0.7 9.0 4.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Apt1 PF10351.4 ETO07406.1 - 8.6 5.0 7.7 12 4.5 5.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain F-box PF00646.28 ETO07407.1 - 0.0004 19.9 0.0 0.001 18.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain WD40 PF00400.27 ETO07411.1 - 1e-31 107.6 7.5 6.2e-11 41.7 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO07411.1 - 2e-12 46.0 1.9 2.2e-05 22.7 0.9 3.3 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO07411.1 - 0.0014 17.4 1.0 0.38 9.4 0.1 2.9 2 1 1 3 3 3 2 Nup133 N terminal like Aldo_ket_red PF00248.16 ETO07412.1 - 2.8e-08 32.9 0.1 3.1e-08 32.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glycoprotein_B PF00606.13 ETO07412.1 - 0.13 10.2 0.0 0.15 10.0 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B Ras PF00071.17 ETO07413.1 - 1.3e-25 89.6 0.1 1.5e-25 89.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO07413.1 - 8.7e-07 29.4 0.0 1.1e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO07413.1 - 0.00011 21.5 0.0 0.00012 21.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 ETO07413.1 - 0.032 13.4 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 ETO07413.1 - 0.12 11.7 0.0 1.9 7.8 0.0 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF1687 PF07955.6 ETO07414.1 - 0.048 13.6 1.5 0.077 12.9 1.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1687) RPM2 PF08579.6 ETO07414.1 - 0.079 13.0 4.5 0.11 12.6 2.9 1.3 1 1 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) DUF3019 PF11456.3 ETO07414.1 - 0.087 13.1 2.4 0.096 13.0 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3019) U-box PF04564.10 ETO07416.1 - 1.5e-11 44.0 0.1 2.3e-10 40.2 0.1 2.6 1 1 0 1 1 1 1 U-box domain MIT PF04212.13 ETO07416.1 - 0.026 14.4 0.3 0.12 12.2 0.1 2.1 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Tnp_P_element PF12017.3 ETO07416.1 - 0.037 13.2 2.3 0.73 9.0 1.1 2.1 2 0 0 2 2 2 0 Transposase protein FliJ PF02050.11 ETO07416.1 - 0.42 10.6 13.0 0.29 11.2 1.1 2.6 1 1 1 2 2 2 0 Flagellar FliJ protein TPR_1 PF00515.23 ETO07417.1 - 1.4e-16 59.3 12.4 2.1e-05 23.9 0.0 7.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 ETO07417.1 - 5.3e-16 58.3 10.6 5.9e-06 26.1 0.3 4.9 2 1 1 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO07417.1 - 4e-12 44.9 8.8 0.015 15.0 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO07417.1 - 1.4e-11 43.3 10.0 0.079 12.9 0.6 6.9 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO07417.1 - 3.8e-11 41.9 13.8 0.053 13.3 0.8 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO07417.1 - 1.6e-10 40.4 17.5 0.00089 18.8 0.7 6.0 4 1 1 6 6 6 4 TPR repeat TPR_14 PF13428.1 ETO07417.1 - 3.5e-06 27.1 0.2 5 8.0 0.0 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO07417.1 - 0.0011 19.2 13.0 1.7 9.2 0.4 5.7 6 1 0 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO07417.1 - 0.0012 18.9 19.5 0.0099 15.9 1.2 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 ETO07417.1 - 0.0026 18.4 5.5 1.2 9.9 0.0 4.9 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETO07417.1 - 0.0073 16.2 0.2 9.8 6.2 0.1 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO07417.1 - 0.098 13.0 11.2 1.3 9.3 0.1 5.2 4 2 2 6 6 6 0 Tetratricopeptide repeat Apc5 PF12862.2 ETO07417.1 - 0.62 9.9 9.1 1.7 8.5 2.1 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_17 PF13431.1 ETO07417.1 - 0.74 10.1 6.1 18 5.8 0.1 5.6 6 1 1 7 7 7 0 Tetratricopeptide repeat Kelch_4 PF13418.1 ETO07418.1 - 3.7e-48 161.0 14.0 8.9e-12 44.5 0.1 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO07418.1 - 1.3e-42 142.9 22.0 1.9e-14 53.3 0.1 7.9 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO07418.1 - 1.1e-36 124.2 15.8 3.2e-09 36.5 0.0 6.8 7 0 0 7 7 7 6 Kelch motif Kelch_1 PF01344.20 ETO07418.1 - 1.1e-36 124.0 1.7 7.7e-13 47.7 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 ETO07418.1 - 2.8e-34 115.8 9.3 1.7e-08 34.3 0.0 6.6 4 1 2 6 6 6 6 Kelch motif Kelch_2 PF07646.10 ETO07418.1 - 7.3e-31 104.7 11.9 4.3e-08 32.6 0.0 6.8 7 0 0 7 7 7 5 Kelch motif RPEL PF02755.10 ETO07418.1 - 0.002 17.4 0.0 0.53 9.6 0.0 2.6 2 0 0 2 2 2 2 RPEL repeat DOT1 PF08123.8 ETO07420.1 - 3.1e-14 52.7 0.2 6.5e-14 51.7 0.1 1.5 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_4 PF02390.12 ETO07420.1 - 0.0013 17.8 0.1 0.0039 16.2 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_18 PF12847.2 ETO07420.1 - 0.0057 17.2 0.0 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 ETO07420.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase DUF650 PF04894.7 ETO07421.1 - 0.058 12.8 0.1 0.076 12.4 0.0 1.2 1 1 0 1 1 1 0 Archaeal protein of unknown function (DUF650) SRP40_C PF05022.7 ETO07421.1 - 0.069 13.6 0.1 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 SRP40, C-terminal domain DUF4236 PF14020.1 ETO07421.1 - 1.8 8.7 4.2 0.23 11.5 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4236) Abhydrolase_3 PF07859.8 ETO07422.1 - 5.4e-05 22.8 0.1 8.4e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETO07422.1 - 0.0044 16.7 0.0 0.007 16.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ribosomal_S19 PF00203.16 ETO07423.1 - 1.8e-26 91.5 0.8 3.8e-26 90.5 0.6 1.6 1 0 0 1 1 1 1 Ribosomal protein S19 FemAB PF02388.11 ETO07423.1 - 0.59 8.7 4.4 0.82 8.2 3.0 1.2 1 0 0 1 1 1 0 FemAB family Pkinase PF00069.20 ETO07424.1 - 2.1e-09 36.9 0.0 3.5e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LAP1C PF05609.7 ETO07424.1 - 0.043 12.4 6.1 0.057 12.0 4.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Trp_Tyr_perm PF03222.8 ETO07425.1 - 1.5e-05 24.0 1.1 1.5e-05 24.0 0.8 1.7 1 1 1 2 2 2 1 Tryptophan/tyrosine permease family TraD_N PF12615.3 ETO07425.1 - 6 7.2 14.7 1.5 9.2 0.4 3.5 1 1 2 3 3 3 0 F sex factor protein N terminal Aa_trans PF01490.13 ETO07426.1 - 2.1 6.7 7.3 2.7 6.3 4.3 1.7 2 1 0 2 2 2 0 Transmembrane amino acid transporter protein RRM_1 PF00076.17 ETO07427.1 - 3.5e-21 74.6 8.9 2.2e-08 33.6 0.2 3.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO07427.1 - 2.6e-13 49.7 3.0 0.00013 21.8 0.1 3.6 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO07427.1 - 2.8e-09 36.6 1.9 0.098 12.5 0.1 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETO07427.1 - 0.0042 16.8 0.7 2.5 7.9 0.1 3.7 3 2 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 ETO07427.1 - 0.016 15.0 2.0 1.3 8.8 0.1 3.3 3 0 0 3 3 3 0 RNA binding motif PPP4R2 PF09184.6 ETO07429.1 - 0.0045 16.5 29.4 0.0045 16.5 20.4 1.8 2 0 0 2 2 2 1 PPP4R2 DUF2201_N PF13203.1 ETO07429.1 - 0.018 14.2 12.6 0.029 13.5 8.7 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Daxx PF03344.10 ETO07429.1 - 0.1 11.0 28.4 0.14 10.5 19.7 1.2 1 0 0 1 1 1 0 Daxx Family NOA36 PF06524.7 ETO07429.1 - 0.13 11.5 19.6 0.29 10.3 13.6 1.6 1 0 0 1 1 1 0 NOA36 protein SprA-related PF12118.3 ETO07429.1 - 0.16 11.2 25.7 0.26 10.5 17.8 1.3 1 0 0 1 1 1 0 SprA-related family Macoilin PF09726.4 ETO07429.1 - 0.64 8.2 31.5 0.82 7.8 21.8 1.2 1 0 0 1 1 1 0 Transmembrane protein Trypan_PARP PF05887.6 ETO07429.1 - 1.2 8.9 12.3 1.9 8.2 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) BUD22 PF09073.5 ETO07429.1 - 1.7 7.6 34.8 1.7 7.6 23.3 1.5 1 1 0 1 1 1 0 BUD22 Utp14 PF04615.8 ETO07429.1 - 2.4 6.2 37.4 3.6 5.6 25.9 1.2 1 0 0 1 1 1 0 Utp14 protein GLYCAM-1 PF05242.6 ETO07430.1 - 0.065 13.1 0.9 0.12 12.3 0.6 1.3 1 0 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) DUF2213 PF09979.4 ETO07430.1 - 0.081 12.5 0.1 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2213) AATF-Che1 PF13339.1 ETO07430.1 - 5.2 7.2 11.0 2.9 8.0 1.2 3.1 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor Synapsin_C PF02750.9 ETO07431.1 - 1.6e-28 99.2 0.0 2.2e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Synapsin, ATP binding domain Synapsin_C PF02750.9 ETO07432.1 - 6.5e-19 67.8 0.0 9.2e-19 67.3 0.0 1.2 1 0 0 1 1 1 1 Synapsin, ATP binding domain Synapsin PF02078.11 ETO07432.1 - 6e-08 32.7 0.0 1.2e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Synapsin, N-terminal domain P22_Tail-4 PF11650.3 ETO07434.1 - 0.086 12.3 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 P22 tail accessory factor DUF3279 PF11682.3 ETO07435.1 - 0.074 12.6 0.4 0.12 11.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3279) DUF2693 PF10902.3 ETO07435.1 - 0.21 11.5 1.6 0.34 10.8 0.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2693) DUF2971 PF11185.3 ETO07435.1 - 0.28 11.9 2.7 0.38 11.5 1.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2971) XPG_I PF00867.13 ETO07436.1 - 1.5e-24 85.8 0.0 6.3e-24 83.8 0.0 2.2 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 ETO07436.1 - 2.9e-05 23.6 1.8 0.00011 21.7 0.0 2.6 2 1 0 3 3 3 1 XPG domain containing zf-RanBP PF00641.13 ETO07436.1 - 0.45 9.6 31.2 0.4 9.8 0.5 3.4 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others Mem_trans PF03547.13 ETO07436.1 - 4 5.6 3.9 0.89 7.7 0.2 1.8 2 0 0 2 2 2 0 Membrane transport protein Nop14 PF04147.7 ETO07437.1 - 0.00043 18.3 35.3 0.00052 18.0 24.5 1.0 1 0 0 1 1 1 1 Nop14-like family DUF2457 PF10446.4 ETO07437.1 - 0.0009 18.0 31.3 0.0011 17.8 21.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Daxx PF03344.10 ETO07437.1 - 0.052 12.0 26.9 0.059 11.8 18.7 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 ETO07437.1 - 0.094 10.7 24.1 0.12 10.3 16.7 1.3 1 0 0 1 1 1 0 CDC45-like protein LEDGF PF11467.3 ETO07437.1 - 0.13 11.9 4.6 2.6 7.7 0.1 3.2 2 1 1 3 3 3 0 Lens epithelium-derived growth factor (LEDGF) PLRV_ORF5 PF01690.12 ETO07437.1 - 0.35 9.9 18.9 0.43 9.6 13.1 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Cwf_Cwc_15 PF04889.7 ETO07437.1 - 0.64 9.6 40.0 0.59 9.7 27.0 1.3 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1509 PF07420.6 ETO07437.1 - 2.8 7.1 9.8 3.9 6.6 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) BUD22 PF09073.5 ETO07437.1 - 4.7 6.1 29.4 7.4 5.5 20.4 1.3 1 0 0 1 1 1 0 BUD22 SMP_2 PF10144.4 ETO07440.1 - 0.015 14.4 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin WD40 PF00400.27 ETO07441.1 - 7.3e-15 54.1 12.5 1e-07 31.5 0.3 3.7 3 1 1 4 4 4 3 WD domain, G-beta repeat WD40 PF00400.27 ETO07442.1 - 2.6e-138 445.5 50.8 7.6e-13 47.8 0.4 14.8 14 1 0 14 14 14 13 WD domain, G-beta repeat NACHT PF05729.7 ETO07442.1 - 2.1e-10 40.4 0.0 4.4e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Cytochrom_D1 PF02239.11 ETO07442.1 - 1.8e-07 29.8 5.4 0.23 9.6 0.1 5.2 1 1 3 6 6 6 3 Cytochrome D1 heme domain Str_synth PF03088.11 ETO07442.1 - 7.4e-06 25.9 5.7 2.3 8.2 0.0 7.8 7 3 2 9 9 8 1 Strictosidine synthase AAA_22 PF13401.1 ETO07442.1 - 2.6e-05 24.3 0.0 8.5e-05 22.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain Pentapeptide PF00805.17 ETO07442.1 - 0.00035 19.7 0.4 0.0016 17.6 0.1 1.8 1 1 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 ETO07442.1 - 0.00054 19.7 0.4 0.0017 18.2 0.3 1.9 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.1 ETO07442.1 - 0.00093 18.9 0.2 0.003 17.3 0.1 1.9 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Gmad1 PF10647.4 ETO07442.1 - 0.00096 18.6 0.0 0.81 9.0 0.0 4.0 2 1 0 3 3 3 1 Lipoprotein LpqB beta-propeller domain AAA_18 PF13238.1 ETO07442.1 - 0.0011 19.3 0.9 0.0072 16.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain PD40 PF07676.7 ETO07442.1 - 0.046 13.3 29.3 16 5.2 0.0 8.6 9 0 0 9 9 9 0 WD40-like Beta Propeller Repeat AAA_16 PF13191.1 ETO07442.1 - 0.11 12.4 0.4 1.7 8.6 0.0 2.5 2 1 1 3 3 3 0 AAA ATPase domain RRM_1 PF00076.17 ETO07443.1 - 8.4e-19 66.9 3.8 1.4e-18 66.2 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO07443.1 - 6.2e-17 61.3 0.0 6.6e-15 54.8 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO07443.1 - 3.8e-07 29.8 3.2 4.7e-07 29.5 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_polI_A14 PF08203.6 ETO07443.1 - 4.7 7.5 7.4 36 4.6 5.1 2.7 1 1 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 TFIIF_alpha PF05793.7 ETO07444.1 - 2.7e-05 22.7 11.4 2.7e-05 22.7 7.9 2.1 2 0 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Daxx PF03344.10 ETO07444.1 - 0.1 11.0 53.7 0.35 9.2 17.6 2.1 2 0 0 2 2 2 0 Daxx Family RRN3 PF05327.6 ETO07444.1 - 0.32 9.0 27.8 0.42 8.6 5.1 2.3 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 LMBR1 PF04791.11 ETO07444.1 - 0.51 8.8 10.1 0.11 11.0 1.4 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein Tim54 PF11711.3 ETO07444.1 - 0.57 8.7 18.7 0.28 9.7 1.2 2.4 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Hid1 PF12722.2 ETO07444.1 - 3.8 5.0 23.3 1.7 6.2 5.3 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein SAPS PF04499.10 ETO07444.1 - 4.3 5.8 27.8 2.1 6.8 8.3 2.2 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein HSP90 PF00183.13 ETO07444.1 - 5 5.4 37.9 0.57 8.5 13.2 2.4 2 0 0 2 2 2 0 Hsp90 protein SDA1 PF05285.7 ETO07444.1 - 6.5 5.9 56.4 1.2 8.3 18.8 2.3 2 0 0 2 2 2 0 SDA1 Nop14 PF04147.7 ETO07444.1 - 7.6 4.3 63.5 2.6 5.8 15.1 2.2 2 0 0 2 2 2 0 Nop14-like family Ras PF00071.17 ETO07445.1 - 9.3e-50 168.1 1.8 3.3e-24 85.1 0.1 2.2 1 1 1 2 2 2 2 Ras family Miro PF08477.8 ETO07445.1 - 7.8e-14 52.1 0.2 9e-07 29.4 0.0 2.3 1 1 1 2 2 2 2 Miro-like protein Arf PF00025.16 ETO07445.1 - 1.2e-11 44.2 0.1 1.5e-05 24.3 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETO07445.1 - 0.027 13.6 0.1 0.27 10.3 0.0 2.0 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region LETM1 PF07766.8 ETO07446.1 - 0.029 13.4 0.3 0.036 13.0 0.2 1.1 1 0 0 1 1 1 0 LETM1-like protein Glyco_tran_28_C PF04101.11 ETO07447.1 - 2.4e-23 82.6 0.0 2.9e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 ETO07447.1 - 8.8e-06 25.1 0.0 1.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 1 NAD_Gly3P_dh_C PF07479.9 ETO07447.1 - 0.11 12.2 0.3 0.19 11.4 0.2 1.4 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus IL7 PF01415.11 ETO07447.1 - 1.8 8.2 6.4 3.1 7.4 3.6 1.9 1 1 1 2 2 2 0 Interleukin 7/9 family DUF2192 PF09958.4 ETO07448.1 - 0.03 13.5 0.1 0.057 12.6 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2192) WD40 PF00400.27 ETO07449.1 - 3.1e-36 121.9 5.7 3.7e-11 42.4 0.0 5.3 4 2 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO07449.1 - 4.2e-05 21.8 0.1 0.066 11.3 0.0 3.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO07449.1 - 9.2e-05 21.3 0.4 0.017 13.9 0.0 2.5 1 1 1 2 2 2 2 Nup133 N terminal like eIF2A PF08662.6 ETO07449.1 - 0.0095 15.6 0.0 0.58 9.8 0.0 2.7 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 ETO07449.1 - 0.018 14.1 0.3 0.79 8.7 0.0 2.4 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal SET_assoc PF11767.3 ETO07449.1 - 0.099 11.9 0.6 0.75 9.1 0.3 2.2 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Resistin PF06954.6 ETO07449.1 - 0.11 12.8 0.0 1.1 9.5 0.0 2.4 2 1 0 2 2 2 0 Resistin Ras PF00071.17 ETO07450.1 - 1.7e-11 43.7 0.0 2.5e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO07450.1 - 0.019 15.4 0.0 0.038 14.4 0.0 1.6 1 1 0 1 1 1 0 Miro-like protein MMR_HSR1 PF01926.18 ETO07450.1 - 0.045 13.7 0.1 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 ETO07450.1 - 0.055 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 ETO07450.1 - 0.072 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain WD40 PF00400.27 ETO07451.1 - 9.5e-55 180.6 29.7 2.5e-11 42.9 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO07451.1 - 3.3e-12 45.3 6.1 2.6e-05 22.5 0.9 5.4 1 1 3 4 4 4 3 Nucleoporin Nup120/160 WD40 PF00400.27 ETO07453.1 - 8.1e-84 272.8 13.1 8.9e-15 53.9 0.3 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO07453.1 - 4.7e-12 46.0 0.3 7.4e-06 25.8 0.0 3.4 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO07453.1 - 6.9e-12 44.2 4.9 0.00035 18.8 0.5 5.4 1 1 5 6 6 6 5 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO07453.1 - 1e-09 37.1 0.6 8.7e-05 20.9 0.0 3.4 2 2 1 3 3 3 3 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 ETO07453.1 - 2.2e-06 26.7 0.4 0.17 10.6 0.0 3.2 1 1 1 3 3 3 2 Coatomer WD associated region Nucleoporin_N PF08801.6 ETO07453.1 - 1.9e-05 23.5 13.4 0.23 10.1 0.5 5.4 1 1 2 3 3 3 3 Nup133 N terminal like PLD_C PF12357.3 ETO07453.1 - 6.8e-05 22.3 0.3 12 5.4 0.0 5.5 3 2 2 6 6 6 0 Phospholipase D C terminal PQQ_2 PF13360.1 ETO07453.1 - 0.0001 21.8 1.8 0.00068 19.1 1.1 2.4 1 1 0 1 1 1 1 PQQ-like domain Str_synth PF03088.11 ETO07453.1 - 0.00015 21.6 1.4 7.1 6.7 0.0 5.0 2 1 4 7 7 6 1 Strictosidine synthase BBS2_Mid PF14783.1 ETO07453.1 - 0.0004 20.1 2.5 0.52 10.1 0.2 4.3 3 1 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region B_lectin PF01453.19 ETO07453.1 - 0.0011 18.8 4.4 0.84 9.5 0.1 3.9 1 1 3 4 4 4 2 D-mannose binding lectin PD40 PF07676.7 ETO07453.1 - 0.0013 18.3 7.8 17 5.1 0.0 5.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat DUF3601 PF12208.3 ETO07453.1 - 0.0022 17.9 0.1 24 4.9 0.0 4.4 3 1 1 4 4 4 0 Domain of unknown function (DUF3601) PSII_BNR PF14870.1 ETO07453.1 - 0.0035 16.3 0.3 0.0064 15.5 0.1 1.6 1 1 0 1 1 1 1 Photosynthesis system II assembly factor YCF48 DUF3732 PF12532.3 ETO07453.1 - 0.0087 15.6 0.3 1.1 8.7 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3732) Nbas_N PF15492.1 ETO07453.1 - 0.031 13.4 1.9 5.2 6.0 0.0 3.7 1 1 4 5 5 5 0 Neuroblastoma-amplified sequence, N terminal Vps16_N PF04841.8 ETO07453.1 - 0.033 12.7 0.1 0.41 9.1 0.0 2.2 1 1 1 2 2 2 0 Vps16, N-terminal region HARP PF07443.8 ETO07453.1 - 0.083 12.2 0.0 0.47 9.8 0.0 2.3 2 0 0 2 2 2 0 HepA-related protein (HARP) Proteasome_A_N PF10584.4 ETO07453.1 - 2 7.8 9.9 19 4.7 0.0 5.1 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 ETO07454.1 - 1.3e-76 249.9 15.2 3.6e-13 48.8 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO07454.1 - 6.1e-08 31.2 8.6 0.0022 16.2 0.1 4.2 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO07454.1 - 5.3e-05 21.6 0.7 0.25 9.5 0.0 2.9 1 1 1 3 3 3 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO07454.1 - 0.0012 18.4 3.5 0.015 14.7 2.5 2.3 1 1 0 1 1 1 1 PQQ-like domain B_lectin PF01453.19 ETO07454.1 - 0.02 14.7 5.2 0.078 12.8 2.1 2.7 1 1 1 2 2 2 0 D-mannose binding lectin Str_synth PF03088.11 ETO07454.1 - 0.028 14.4 0.0 6.5 6.8 0.0 3.5 2 1 0 3 3 3 0 Strictosidine synthase Hira PF07569.6 ETO07454.1 - 0.038 13.1 0.2 6 6.0 0.0 3.9 2 1 3 5 5 5 0 TUP1-like enhancer of split PD40 PF07676.7 ETO07454.1 - 4.8 6.9 11.6 53 3.6 0.0 5.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 ETO07455.1 - 4.9e-25 86.4 6.4 2.4e-12 46.2 0.7 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO07455.1 - 0.07 11.2 0.5 3.1 5.8 0.4 2.6 1 1 0 1 1 1 0 Nucleoporin Nup120/160 vATP-synt_AC39 PF01992.11 ETO07456.1 - 2.2e-24 86.2 3.1 2.1e-23 83.0 2.2 1.9 1 1 0 1 1 1 1 ATP synthase (C/AC39) subunit Peptidase_M15_3 PF08291.6 ETO07457.1 - 5.8e-17 61.4 0.0 1.4e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase M15 DUF912 PF06024.7 ETO07457.1 - 0.00012 22.0 0.8 0.0002 21.3 0.5 1.3 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Plasmodium_Vir PF05795.6 ETO07457.1 - 0.00031 20.0 0.1 0.00042 19.6 0.1 1.2 1 0 0 1 1 1 1 Plasmodium vivax Vir protein TMEM154 PF15102.1 ETO07457.1 - 0.00043 20.0 0.9 0.00066 19.4 0.6 1.2 1 0 0 1 1 1 1 TMEM154 protein family CD34_antigen PF06365.7 ETO07457.1 - 0.0017 18.0 0.1 0.0025 17.5 0.1 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family DUF2370 PF10176.4 ETO07457.1 - 0.0028 17.0 0.2 0.0039 16.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Baculo_E56 PF04639.7 ETO07457.1 - 0.0035 16.0 0.2 0.006 15.2 0.1 1.3 1 0 0 1 1 1 1 Baculoviral E56 protein, specific to ODV envelope Rifin_STEVOR PF02009.11 ETO07457.1 - 0.0054 16.4 0.1 0.0076 15.9 0.1 1.2 1 0 0 1 1 1 1 Rifin/stevor family DUF4448 PF14610.1 ETO07457.1 - 0.0079 15.7 0.0 0.0099 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Lamp PF01299.12 ETO07457.1 - 0.01 15.0 2.8 0.01 15.0 1.9 1.7 1 1 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) DUF2520 PF10728.4 ETO07457.1 - 0.024 14.0 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) Protocadherin PF08374.6 ETO07457.1 - 0.033 13.8 0.1 0.063 12.9 0.1 1.5 1 0 0 1 1 1 0 Protocadherin DAG1 PF05454.6 ETO07457.1 - 0.042 13.0 0.0 0.059 12.5 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Peptidase_M56 PF05569.6 ETO07457.1 - 0.055 12.4 0.1 0.073 12.0 0.1 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 Chordopox_A13L PF05961.6 ETO07457.1 - 0.083 12.8 0.5 0.083 12.8 0.4 1.9 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Peptidase_M15_2 PF05951.8 ETO07457.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) DUF1180 PF06679.7 ETO07457.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Glycophorin_A PF01102.13 ETO07457.1 - 0.19 11.4 3.9 0.49 10.1 2.7 1.8 1 1 0 1 1 1 0 Glycophorin A DUF3827 PF12877.2 ETO07457.1 - 0.29 9.1 4.5 0.14 10.2 1.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3827) RPEL PF02755.10 ETO07458.1 - 0.018 14.3 0.2 0.43 9.9 0.0 2.9 2 0 0 2 2 2 0 RPEL repeat Homez PF11569.3 ETO07458.1 - 0.2 10.7 7.2 0.021 13.9 1.5 1.9 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez NAD_binding_1 PF00175.16 ETO07458.1 - 0.36 11.4 2.5 0.81 10.2 0.4 2.8 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain CENP-B_dimeris PF09026.5 ETO07460.1 - 3.7 7.8 9.1 4.5 7.5 1.0 3.1 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Ni_hydr_CYTB PF01292.15 ETO07461.1 - 1.7 8.0 10.0 5.3 6.3 6.1 2.4 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 DUF443 PF04276.7 ETO07461.1 - 7.4 5.9 14.0 0.027 13.9 1.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF443) zf-TRAF PF02176.13 ETO07462.1 - 4.4e-06 26.9 4.5 4.4e-06 26.9 3.1 2.7 3 1 0 3 3 3 1 TRAF-type zinc finger Fzo_mitofusin PF04799.8 ETO07462.1 - 0.0054 16.1 5.4 0.0054 16.1 3.8 2.1 2 0 0 2 2 2 1 fzo-like conserved region DUF1697 PF08002.6 ETO07462.1 - 0.027 14.5 1.1 0.049 13.6 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1697) Seryl_tRNA_N PF02403.17 ETO07462.1 - 1.4 8.9 13.6 0.38 10.7 6.4 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF755 PF05501.6 ETO07462.1 - 4.1 7.4 10.1 1.1 9.3 3.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) RVT_1 PF00078.22 ETO07463.1 - 1.4e-09 37.6 0.0 6.8e-09 35.3 0.0 2.0 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ndc1_Nup PF09531.5 ETO07463.1 - 3.9 5.7 11.9 6.4 5.0 8.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Kinesin PF00225.18 ETO07464.1 - 1.3e-07 30.6 7.7 1.3e-07 30.6 5.3 1.5 1 1 0 1 1 1 1 Kinesin motor domain Peptidase_M15_2 PF05951.8 ETO07464.1 - 0.01 15.2 0.6 0.021 14.2 0.4 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) Terpene_synth_C PF03936.11 ETO07464.1 - 0.027 13.6 2.3 0.12 11.6 0.9 2.0 1 1 1 2 2 2 0 Terpene synthase family, metal binding domain TFX_C PF14601.1 ETO07464.1 - 0.086 12.6 1.0 4.2 7.2 0.0 2.8 3 0 0 3 3 3 0 DNA_binding protein, TFX, C-term SPG48 PF14764.1 ETO07464.1 - 0.11 11.0 0.1 0.15 10.5 0.1 1.2 1 0 0 1 1 1 0 AP-5 complex subunit, vesicle trafficking RNase_H2-Ydr279 PF09468.5 ETO07465.1 - 0.38 9.9 17.0 0.69 9.0 11.8 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF605 PF04652.11 ETO07465.1 - 0.58 9.4 38.8 0.86 8.9 26.9 1.1 1 0 0 1 1 1 0 Vta1 like NARP1 PF12569.3 ETO07465.1 - 1.7 7.3 22.9 2.5 6.7 15.9 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 MIP-T3 PF10243.4 ETO07465.1 - 2.1 6.7 45.8 3 6.2 31.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Exo_endo_phos_2 PF14529.1 ETO07467.1 - 0.0061 16.1 4.8 0.015 14.8 3.3 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase N_Asn_amidohyd PF14736.1 ETO07467.1 - 0.024 13.5 0.3 0.038 12.8 0.2 1.3 1 0 0 1 1 1 0 Protein N-terminal asparagine amidohydrolase Intimin_C PF07979.6 ETO07468.1 - 0.026 14.7 0.2 0.057 13.6 0.1 1.5 1 0 0 1 1 1 0 Intimin C-type lectin domain Di19_C PF14571.1 ETO07468.1 - 5 7.5 14.6 0.078 13.2 2.4 2.5 1 1 0 2 2 2 0 Stress-induced protein Di19, C-terminal DUF3435 PF11917.3 ETO07468.1 - 7.2 5.2 15.3 4.5 5.8 5.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3435) YqfQ PF14181.1 ETO07468.1 - 7.3 6.5 19.8 5.9 6.9 4.6 2.3 2 0 0 2 2 2 0 YqfQ-like protein AFT PF08731.6 ETO07469.1 - 0.024 14.8 2.5 0.042 14.0 1.7 1.3 1 0 0 1 1 1 0 Transcription factor AFT EphA2_TM PF14575.1 ETO07469.1 - 0.057 13.8 0.2 0.094 13.1 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 ETO07469.1 - 0.081 12.6 0.4 0.16 11.6 0.3 1.4 1 0 0 1 1 1 0 TMEM154 protein family SART-1 PF03343.8 ETO07469.1 - 0.12 10.7 6.0 0.13 10.5 4.2 1.1 1 0 0 1 1 1 0 SART-1 family BLVR PF06375.6 ETO07469.1 - 1.8 8.3 7.2 2.6 7.8 5.0 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) CDC45 PF02724.9 ETO07470.1 - 0.1 10.5 12.2 0.11 10.4 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4196 PF13846.1 ETO07470.1 - 0.11 12.7 14.6 0.25 11.6 10.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4196) DUF1510 PF07423.6 ETO07470.1 - 0.76 9.1 17.9 1.1 8.5 12.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Herpes_DNAp_acc PF04929.7 ETO07470.1 - 5.2 5.9 8.2 6.2 5.6 5.7 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Pap_E4 PF02711.9 ETO07471.1 - 0.41 11.4 6.0 0.75 10.6 4.2 1.5 1 0 0 1 1 1 0 E4 protein Di19_C PF14571.1 ETO07471.1 - 0.47 10.8 4.9 0.92 9.8 3.4 1.7 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal CDC45 PF02724.9 ETO07471.1 - 2.2 6.2 12.6 2.3 6.1 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.12 ETO07471.1 - 3.1 7.5 9.3 4.1 7.1 6.4 1.2 1 0 0 1 1 1 0 DDHD domain YqfQ PF14181.1 ETO07472.1 - 5.1 7.1 13.2 5.3 7.0 9.1 1.1 1 0 0 1 1 1 0 YqfQ-like protein Agouti PF05039.7 ETO07472.1 - 9.2 6.6 6.6 13 6.2 4.6 1.3 1 0 0 1 1 1 0 Agouti protein Methyltransf_11 PF08241.7 ETO07474.1 - 1.9e-15 57.1 0.0 2.6e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETO07474.1 - 9e-13 48.4 0.0 1.3e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO07474.1 - 1.9e-11 43.7 0.0 2.1e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 ETO07474.1 - 2.4e-11 43.1 0.0 2.7e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_18 PF12847.2 ETO07474.1 - 6.9e-11 42.7 0.0 9.8e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETO07474.1 - 7e-11 42.1 0.0 7.5e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 ETO07474.1 - 1.8e-10 40.5 0.0 2.5e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_12 PF08242.7 ETO07474.1 - 3.1e-09 37.2 0.0 4.3e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 ETO07474.1 - 1.4e-06 27.8 0.0 1.6e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_26 PF13659.1 ETO07474.1 - 1.3e-05 25.1 0.0 1.9e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 ETO07474.1 - 0.00018 20.8 0.0 0.00026 20.3 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain MTS PF05175.9 ETO07474.1 - 0.00021 20.7 0.0 0.00027 20.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 ETO07474.1 - 0.0034 16.5 0.0 0.0045 16.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 ETO07474.1 - 0.0053 15.8 0.0 0.0071 15.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase tRNA_U5-meth_tr PF05958.6 ETO07474.1 - 0.015 14.0 0.0 0.021 13.5 0.0 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_4 PF02390.12 ETO07474.1 - 0.057 12.4 0.0 0.082 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase WD40 PF00400.27 ETO07475.1 - 0.00084 19.1 3.7 0.0049 16.7 1.8 2.4 2 0 0 2 2 2 1 WD domain, G-beta repeat PHP_C PF13263.1 ETO07476.1 - 0.043 13.3 0.0 0.086 12.3 0.0 1.5 1 0 0 1 1 1 0 PHP-associated DUF788 PF05620.6 ETO07477.1 - 9.7 6.0 9.9 0.36 10.6 1.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF788) ART PF01129.13 ETO07478.1 - 0.014 14.5 0.1 0.02 14.0 0.0 1.3 1 1 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase tRNA_synt_1c_R2 PF04557.10 ETO07479.1 - 0.014 16.0 6.9 0.02 15.5 4.8 1.2 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 RNA_pol_Rpc4 PF05132.9 ETO07479.1 - 0.54 10.2 4.6 0.62 10.0 3.2 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Hemopexin PF00045.14 ETO07480.1 - 0.039 13.6 0.9 0.23 11.2 0.0 2.8 3 0 0 3 3 3 0 Hemopexin YARHG PF13308.1 ETO07482.1 - 0.051 13.1 1.8 0.42 10.2 0.4 2.3 2 0 0 2 2 2 0 YARHG domain Transposase_24 PF03004.9 ETO07482.1 - 0.42 10.5 5.1 12 5.7 2.0 2.5 2 1 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) WD40 PF00400.27 ETO07483.1 - 6.3e-59 193.8 18.6 7.1e-11 41.5 0.0 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO07483.1 - 5.5e-11 41.2 10.9 0.0026 15.9 0.2 6.0 1 1 5 6 6 6 6 Nucleoporin Nup120/160 Reo_sigmaC PF04582.7 ETO07483.1 - 0.013 14.6 0.8 0.38 9.8 1.5 2.3 2 1 0 2 2 2 0 Reovirus sigma C capsid protein HAD PF12710.2 ETO07483.1 - 0.022 14.9 1.8 3.1 7.9 0.0 3.8 3 1 0 4 4 4 0 haloacid dehalogenase-like hydrolase Kelch_6 PF13964.1 ETO07483.1 - 0.037 14.2 14.9 0.62 10.3 0.1 5.7 5 1 1 6 6 6 0 Kelch motif Kelch_2 PF07646.10 ETO07483.1 - 1.3 8.8 5.9 9.6 6.1 0.0 4.1 4 0 0 4 4 4 0 Kelch motif DUF3366 PF11846.3 ETO07485.1 - 0.68 9.7 6.0 1.1 9.1 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) Daxx PF03344.10 ETO07485.1 - 0.72 8.2 53.9 0.84 8.0 37.4 1.0 1 0 0 1 1 1 0 Daxx Family DUF605 PF04652.11 ETO07485.1 - 1.7 7.9 54.3 2.1 7.6 37.6 1.1 1 0 0 1 1 1 0 Vta1 like Ank_2 PF12796.2 ETO07486.1 - 2.9e-15 56.3 0.1 6.8e-10 39.1 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETO07486.1 - 8.8e-15 53.6 0.0 0.00094 18.8 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 ETO07486.1 - 3.5e-07 29.8 0.0 0.22 11.8 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 ETO07486.1 - 5.5e-07 29.6 0.2 0.035 14.3 0.0 3.4 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO07486.1 - 1e-05 25.8 0.1 0.0015 18.9 0.0 2.7 1 1 3 4 4 4 2 Ankyrin repeats (many copies) CTK3 PF12243.3 ETO07486.1 - 1.5e-05 24.6 0.4 2e-05 24.2 0.3 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 Beach PF02138.13 ETO07487.1 - 3.6e-106 354.5 0.1 3.6e-106 354.5 0.1 1.8 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.1 ETO07487.1 - 2e-18 66.1 1.0 1e-12 47.8 0.4 3.2 2 1 0 2 2 2 2 PH domain associated with Beige/BEACH PH PF00169.24 ETO07487.1 - 0.00026 21.1 1.5 0.0022 18.1 0.4 2.8 2 0 0 2 2 2 1 PH domain Sec3-PIP2_bind PF15277.1 ETO07487.1 - 0.0023 17.7 1.1 1.1 9.1 0.1 2.6 2 0 0 2 2 2 2 Exocyst complex component SEC3 N-terminal PIP2 binding PH YmzC PF14157.1 ETO07488.1 - 0.19 11.5 1.4 0.23 11.3 0.2 1.7 2 0 0 2 2 2 0 YmzC-like protein Actin PF00022.14 ETO07489.1 - 1.4e-12 46.7 0.0 1.6e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Actin GTP_EFTU PF00009.22 ETO07489.1 - 0.004 16.6 0.2 0.0081 15.6 0.1 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Methylase_S PF01420.14 ETO07491.1 - 0.025 14.5 0.7 0.043 13.7 0.5 1.3 1 0 0 1 1 1 0 Type I restriction modification DNA specificity domain O-antigen_lig PF13425.1 ETO07491.1 - 0.36 10.8 20.1 0.061 13.3 2.6 2.4 2 1 0 2 2 2 0 O-antigen ligase like membrane protein TRP PF06011.7 ETO07491.1 - 0.58 8.6 17.9 0.08 11.5 9.1 1.8 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel WW PF00397.21 ETO07492.1 - 2.6e-08 33.5 5.6 7.6e-08 32.0 2.8 2.4 2 0 0 2 2 2 1 WW domain DUF4339 PF14237.1 ETO07492.1 - 0.0098 15.4 0.4 0.025 14.1 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4339) Rad51 PF08423.6 ETO07493.1 - 6.4e-117 388.9 0.2 1.5e-116 387.7 0.2 1.5 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.1 ETO07493.1 - 2.1e-11 43.5 0.0 3.2e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 ETO07493.1 - 1e-09 37.9 0.1 1.4e-09 37.4 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 ETO07493.1 - 4e-08 32.6 0.0 6.3e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 KaiC HHH_5 PF14520.1 ETO07493.1 - 5.1e-08 32.9 0.1 1.1e-07 31.8 0.1 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain FHA PF00498.21 ETO07494.1 - 2e-11 43.8 1.0 2e-11 43.8 0.7 2.1 2 0 0 2 2 2 1 FHA domain Cag12 PF13117.1 ETO07495.1 - 0.0042 16.9 0.7 0.42 10.5 0.1 2.9 2 1 1 3 3 3 1 Cag pathogenicity island protein Cag12 AAA PF00004.24 ETO07495.1 - 0.065 13.4 0.1 5.3 7.2 0.0 3.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) WD40 PF00400.27 ETO07496.1 - 9.9e-84 272.5 21.0 1.2e-13 50.4 0.1 7.0 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO07496.1 - 8.4e-16 58.2 3.2 4.6e-06 26.4 0.0 3.3 1 1 4 5 5 5 5 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO07496.1 - 3.2e-12 45.3 4.3 0.0069 14.5 0.0 4.3 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO07496.1 - 1e-08 34.3 10.7 0.033 12.9 0.2 6.0 1 1 6 7 7 7 4 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO07496.1 - 8e-07 27.6 0.0 0.0017 16.7 0.0 2.6 1 1 0 2 2 2 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO07496.1 - 1e-06 28.3 0.1 1.6e-05 24.4 0.0 2.8 1 1 0 1 1 1 1 PQQ-like domain Coatomer_WDAD PF04053.9 ETO07496.1 - 1.1e-05 24.4 0.5 0.055 12.2 0.1 2.4 1 1 1 2 2 2 2 Coatomer WD associated region Ricin_B_lectin PF00652.17 ETO07496.1 - 7.3e-05 22.7 6.4 0.33 10.9 0.3 3.5 1 1 3 4 4 4 3 Ricin-type beta-trefoil lectin domain Nbas_N PF15492.1 ETO07496.1 - 0.00042 19.5 0.5 0.46 9.5 0.0 3.8 1 1 3 5 5 5 1 Neuroblastoma-amplified sequence, N terminal MMS1_N PF10433.4 ETO07496.1 - 0.0016 16.6 0.9 0.21 9.6 0.0 3.3 2 1 1 4 4 4 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DPPIV_N PF00930.16 ETO07496.1 - 0.0029 16.2 0.0 11 4.5 0.0 4.0 2 2 2 5 5 5 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.7 ETO07496.1 - 0.013 15.1 8.3 6.7 6.4 0.0 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO07496.1 - 0.022 15.0 8.8 16 5.8 0.1 4.8 2 2 3 5 5 5 0 Resistin DUF4221 PF13970.1 ETO07496.1 - 0.041 13.1 0.1 0.85 8.8 0.0 3.0 1 1 4 5 5 5 0 Domain of unknown function (DUF4221) NHL PF01436.16 ETO07496.1 - 0.086 12.8 1.3 11 6.1 0.0 3.3 3 0 0 3 3 3 0 NHL repeat Proteasome_A_N PF10584.4 ETO07496.1 - 0.31 10.4 7.0 1.8 7.9 0.1 4.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature ICAM_N PF03921.9 ETO07496.1 - 2.6 7.5 5.3 5.2 6.6 0.3 3.1 3 0 0 3 3 3 0 Intercellular adhesion molecule (ICAM), N-terminal domain Kelch_6 PF13964.1 ETO07497.1 - 1.5e-06 28.0 3.1 0.28 11.4 0.0 4.7 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO07497.1 - 0.0012 18.3 6.1 0.6 9.6 0.1 4.6 4 1 0 4 4 4 2 Kelch motif WD40 PF00400.27 ETO07498.1 - 9.8e-52 171.0 20.2 3.1e-11 42.7 0.4 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO07498.1 - 9.9e-10 37.1 8.5 0.0061 14.7 0.1 5.1 1 1 4 5 5 5 5 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO07498.1 - 0.0061 16.9 5.1 0.019 15.3 3.6 1.9 1 0 0 1 1 1 1 TRAF-type zinc finger DUF1900 PF08954.6 ETO07498.1 - 0.0077 15.7 0.2 1.4 8.4 0.0 4.2 3 1 1 4 4 4 1 Domain of unknown function (DUF1900) DnaJ PF00226.26 ETO07499.1 - 0.0005 19.7 0.9 0.0011 18.7 0.6 1.6 1 0 0 1 1 1 1 DnaJ domain Ank_2 PF12796.2 ETO07500.1 - 1.1e-08 35.3 0.8 1.5e-05 25.2 0.1 3.0 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETO07500.1 - 1.9e-08 33.7 0.0 5.3e-05 22.8 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 ETO07500.1 - 9e-06 25.7 0.5 0.0022 18.1 0.0 3.3 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO07500.1 - 3.7e-05 23.5 0.2 0.013 15.6 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 ETO07500.1 - 0.002 18.6 2.0 0.17 12.4 0.0 3.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) HTH_25 PF13413.1 ETO07500.1 - 0.04 13.5 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Acetyltransf_7 PF13508.1 ETO07501.1 - 3.2e-09 36.8 0.1 4e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETO07501.1 - 5.7e-09 35.8 0.0 6.9e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 ETO07501.1 - 0.0023 18.0 0.0 0.0027 17.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETO07501.1 - 0.006 16.4 0.0 0.0076 16.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 ETO07501.1 - 0.097 12.5 0.0 0.15 11.9 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain A_deaminase PF00962.17 ETO07502.1 - 9.3e-30 103.6 0.0 1.6e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase PF00962.17 ETO07503.1 - 3.4e-16 59.0 0.0 4.4e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Syndecan PF01034.15 ETO07505.1 - 0.002 17.7 2.3 0.0054 16.3 1.6 1.7 1 0 0 1 1 1 1 Syndecan domain 7tm_1 PF00001.16 ETO07505.1 - 0.0046 16.1 0.5 0.0096 15.0 0.3 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRRC37AB_C PF14914.1 ETO07505.1 - 0.057 12.8 0.1 0.15 11.4 0.1 1.7 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain DUF4083 PF13314.1 ETO07505.1 - 1.2 9.0 6.9 1.4 8.7 3.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Protocadherin PF08374.6 ETO07505.1 - 2 8.0 20.5 0.22 11.1 4.0 2.9 2 1 0 2 2 2 0 Protocadherin EphA2_TM PF14575.1 ETO07505.1 - 3.3 8.1 6.2 1.6 9.1 0.9 2.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain EVI2A PF05399.6 ETO07507.1 - 0.094 11.9 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Colicin_V PF02674.11 ETO07508.1 - 1.6 8.6 8.9 1.5 8.6 3.2 2.4 2 1 0 2 2 2 0 Colicin V production protein Tubulin PF00091.20 ETO07509.1 - 1.2e-23 84.1 0.1 1.8e-14 54.1 0.0 2.2 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO07509.1 - 0.00063 19.7 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Lipase_3 PF01764.20 ETO07509.1 - 0.051 13.1 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PUB PF09409.5 ETO07510.1 - 1.9e-05 24.3 3.9 8.8e-05 22.1 2.7 2.1 1 1 0 1 1 1 1 PUB domain DUF3158 PF11358.3 ETO07510.1 - 0.012 15.1 0.6 0.031 13.7 0.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3158) PCI PF01399.22 ETO07510.1 - 3 8.2 9.7 0.51 10.6 0.5 2.8 1 1 2 3 3 3 0 PCI domain CW_binding_1 PF01473.15 ETO07510.1 - 8.6 6.6 8.7 0.96 9.6 2.2 2.2 2 0 0 2 2 2 0 Putative cell wall binding repeat ABC_membrane PF00664.18 ETO07511.1 - 8.4e-12 45.0 0.0 8.4e-12 45.0 0.0 2.7 3 0 0 3 3 3 1 ABC transporter transmembrane region ABC_membrane PF00664.18 ETO07512.1 - 0.003 17.0 2.2 0.003 17.0 1.5 2.8 3 0 0 3 3 3 1 ABC transporter transmembrane region 7TM_GPCR_Srv PF10323.4 ETO07512.1 - 0.011 14.9 0.6 0.011 14.9 0.4 4.0 4 1 0 4 4 4 0 Serpentine type 7TM GPCR chemoreceptor Srv Coatamer_beta_C PF07718.7 ETO07513.1 - 3.8e-54 182.1 0.2 3.8e-54 182.1 0.2 1.8 2 0 0 2 2 2 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.1 ETO07513.1 - 6.5e-53 177.9 4.0 2.2e-44 150.3 0.4 2.5 2 0 0 2 2 2 2 Coatomer beta subunit appendage platform DUF1034 PF06280.7 ETO07513.1 - 0.043 14.2 0.3 0.15 12.4 0.2 1.9 1 0 0 1 1 1 0 Fn3-like domain (DUF1034) ER PF01133.12 ETO07513.1 - 0.044 13.4 0.3 0.25 11.0 0.0 2.2 2 0 0 2 2 2 0 Enhancer of rudimentary DnaJ PF00226.26 ETO07514.1 - 4e-14 52.0 1.7 1.5e-12 47.0 1.2 2.8 1 1 0 1 1 1 1 DnaJ domain Ribosomal_L18ae PF01775.12 ETO07514.1 - 0.052 13.4 1.0 0.084 12.7 0.3 1.7 1 1 1 2 2 2 0 Ribosomal L18ae/LX protein domain Pkinase PF00069.20 ETO07515.1 - 1.6e-59 201.1 0.2 7.1e-59 199.0 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO07515.1 - 3e-29 101.9 0.1 9.4e-29 100.2 0.0 1.8 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 ETO07515.1 - 7.5e-06 25.1 0.1 1.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO07515.1 - 0.00035 20.4 0.9 0.016 14.9 0.1 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 ETO07515.1 - 0.00057 18.9 0.0 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like ABC_tran PF00005.22 ETO07517.1 - 3.2e-14 53.4 0.4 7.7e-12 45.6 0.0 3.0 2 2 0 2 2 2 1 ABC transporter SbcCD_C PF13558.1 ETO07517.1 - 0.012 15.4 0.4 0.076 12.9 0.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC2_membrane_3 PF12698.2 ETO07518.1 - 4.6 6.1 10.7 6.5 5.6 7.4 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Maf PF02545.9 ETO07519.1 - 0.02 14.0 0.4 0.024 13.7 0.3 1.0 1 0 0 1 1 1 0 Maf-like protein TBPIP PF07106.8 ETO07519.1 - 0.026 14.0 5.2 0.032 13.7 3.6 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4285 PF14113.1 ETO07519.1 - 0.061 13.3 0.7 0.067 13.1 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4285) Kinetocho_Slk19 PF12709.2 ETO07519.1 - 0.075 13.1 4.6 0.13 12.3 3.2 1.3 1 0 0 1 1 1 0 Central kinetochore-associated SYCE1 PF15233.1 ETO07519.1 - 0.12 12.3 3.8 0.14 12.0 2.6 1.1 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 MitMem_reg PF13012.1 ETO07519.1 - 0.63 10.1 4.6 0.76 9.8 3.2 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function DUF1087 PF06465.8 ETO07519.1 - 2.8 7.9 7.3 0.83 9.6 2.9 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) Nop14 PF04147.7 ETO07520.1 - 0.011 13.7 6.3 0.014 13.3 4.3 1.1 1 0 0 1 1 1 0 Nop14-like family RP-C_C PF11800.3 ETO07520.1 - 0.057 13.1 2.1 0.1 12.2 1.4 1.5 1 0 0 1 1 1 0 Replication protein C C-terminal region PBP1_TM PF14812.1 ETO07520.1 - 2.5 8.4 7.8 6.7 7.1 5.4 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MIP PF00230.15 ETO07521.1 - 1.2e-18 67.3 0.7 3.9e-18 65.7 0.5 1.7 1 1 0 1 1 1 1 Major intrinsic protein Aminotran_1_2 PF00155.16 ETO07522.1 - 4.5e-78 262.7 0.0 5.8e-78 262.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II CAP_C PF08603.6 ETO07523.1 - 9.4e-18 64.0 14.0 1.4e-17 63.4 9.7 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 ETO07523.1 - 8.6e-08 31.6 12.7 2.1e-07 30.3 8.8 1.8 1 1 0 1 1 1 1 Tubulin binding cofactor C FAD_binding_1 PF00667.15 ETO07523.1 - 0.0099 15.3 0.1 0.024 14.0 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain EIIBC-GUT_N PF03612.9 ETO07523.1 - 1.1 8.8 4.4 0.21 11.1 0.3 1.8 2 1 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4163 PF13739.1 ETO07523.1 - 2.6 8.8 6.5 2.9 8.7 0.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4163) DUF2748 PF10871.3 ETO07525.1 - 0.0022 16.4 0.5 0.003 16.0 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2748) SAM_2 PF07647.12 ETO07526.1 - 2.1e-07 30.7 0.1 0.0015 18.2 0.0 2.3 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO07526.1 - 7.8e-06 25.9 0.0 0.081 13.1 0.0 2.3 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) CorA PF01544.13 ETO07528.1 - 2.1e-34 118.9 0.0 2.1e-34 118.9 0.0 2.7 4 0 0 4 4 4 1 CorA-like Mg2+ transporter protein Usp PF00582.21 ETO07529.1 - 7.6e-19 68.3 0.3 7.1e-18 65.1 0.2 2.0 1 1 0 1 1 1 1 Universal stress protein family DUF460 PF04312.8 ETO07529.1 - 0.0067 15.9 0.3 3.1 7.3 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF460) AAA_26 PF13500.1 ETO07529.1 - 0.087 12.4 0.1 0.12 11.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain WD40 PF00400.27 ETO07530.1 - 2.1e-18 65.4 5.9 1.2e-12 47.1 0.3 3.4 3 1 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO07530.1 - 0.011 13.8 0.3 0.8 7.7 0.1 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 MIP-T3 PF10243.4 ETO07532.1 - 0.0006 18.4 35.8 0.00079 18.0 24.8 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Trypan_PARP PF05887.6 ETO07532.1 - 0.044 13.6 31.8 0.11 12.2 19.5 2.8 2 1 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) POPLD PF08170.7 ETO07532.1 - 0.53 10.1 6.9 0.44 10.4 1.8 2.7 2 0 0 2 2 2 0 POPLD (NUC188) domain CDC45 PF02724.9 ETO07532.1 - 1.2 7.0 19.7 2.1 6.2 13.6 1.3 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 ETO07532.1 - 4.1 5.7 32.5 6.1 5.1 22.5 1.3 1 0 0 1 1 1 0 Daxx Family WD40 PF00400.27 ETO07534.1 - 1.6e-51 170.4 28.7 3.8e-11 42.4 0.3 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO07534.1 - 1.5e-10 39.8 3.3 0.016 13.4 0.0 4.1 2 2 2 4 4 4 4 Nucleoporin Nup120/160 FtsL PF04999.8 ETO07535.1 - 0.027 14.1 1.0 0.25 11.1 0.1 2.4 2 0 0 2 2 2 0 Cell division protein FtsL RRM_6 PF14259.1 ETO07539.1 - 0.015 15.2 0.0 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO07539.1 - 0.035 13.7 0.0 0.16 11.6 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 ETO07539.1 - 0.049 13.6 0.0 0.16 11.9 0.0 1.8 1 1 0 1 1 1 0 RNA binding domain DUF2201_N PF13203.1 ETO07539.1 - 0.055 12.6 8.6 0.047 12.8 5.0 1.5 1 1 0 1 1 1 0 Putative metallopeptidase domain SDA1 PF05285.7 ETO07539.1 - 0.15 11.3 23.0 0.23 10.7 16.0 1.2 1 0 0 1 1 1 0 SDA1 DUF3332 PF11810.3 ETO07539.1 - 1.5 8.4 6.2 1.8 8.2 3.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3332) CPSF73-100_C PF11718.3 ETO07539.1 - 1.7 7.9 10.8 0.34 10.2 5.2 1.6 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term GBP PF02263.14 ETO07540.1 - 0.016 14.2 1.1 0.018 14.1 0.8 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Ceramidase PF05875.7 ETO07542.1 - 3e-51 174.1 19.4 3.8e-51 173.7 13.4 1.1 1 0 0 1 1 1 1 Ceramidase WTX PF09422.5 ETO07543.1 - 0.0051 15.8 5.0 0.0066 15.4 3.5 1.1 1 0 0 1 1 1 1 WTX protein Mem_trans PF03547.13 ETO07543.1 - 0.019 13.3 0.2 0.02 13.1 0.1 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF1777 PF08648.7 ETO07543.1 - 0.051 13.3 16.4 0.07 12.8 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Neur_chan_memb PF02932.11 ETO07543.1 - 0.1 12.4 4.7 0.14 12.0 3.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3959 PF13105.1 ETO07543.1 - 0.51 9.6 8.3 0.76 9.0 5.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) DUF2413 PF10310.4 ETO07543.1 - 0.74 8.5 17.5 0.98 8.1 12.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF572 PF04502.8 ETO07543.1 - 4 6.5 21.3 0.35 10.0 11.5 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF3807 PF12720.2 ETO07543.1 - 8.1 6.5 17.7 12 6.0 12.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) WD40 PF00400.27 ETO07545.1 - 1.6e-59 195.7 19.1 8e-12 44.5 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO07545.1 - 6.4e-13 47.6 1.3 0.0018 16.4 0.0 5.0 3 1 2 5 5 5 4 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO07545.1 - 0.0097 15.2 0.6 0.0097 15.2 0.4 2.7 2 1 1 3 3 3 1 Domain of unknown function (DUF4221) DsrD PF08679.6 ETO07546.1 - 0.22 11.5 0.9 1.2 9.2 0.0 2.0 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) RCC1_2 PF13540.1 ETO07547.1 - 1.1e-08 34.3 1.1 1.1e-06 28.0 0.0 2.7 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat WD40 PF00400.27 ETO07548.1 - 8.6e-19 66.6 19.0 3.1e-09 36.3 0.5 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO07548.1 - 0.00011 20.4 3.1 0.0046 15.1 0.2 2.4 2 1 0 2 2 2 2 Nucleoporin Nup120/160 DUF3122 PF11320.3 ETO07548.1 - 0.11 12.4 0.3 0.19 11.6 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3122) NAD_Gly3P_dh_N PF01210.18 ETO07548.1 - 0.18 11.5 1.6 0.95 9.1 0.1 2.2 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Mac PF12464.3 ETO07550.1 - 0.0038 17.2 0.1 0.01 15.8 0.1 1.7 1 0 0 1 1 1 1 Maltose acetyltransferase WD40 PF00400.27 ETO07551.1 - 2.5e-42 141.2 0.2 3.7e-13 48.7 0.1 4.0 4 0 0 4 4 4 4 WD domain, G-beta repeat eIF2A PF08662.6 ETO07551.1 - 6.9e-07 29.1 0.0 9.2e-05 22.2 0.0 1.8 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO07551.1 - 0.00017 19.8 2.6 0.1 10.7 0.1 3.2 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO07551.1 - 0.0034 15.7 0.0 0.0045 15.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO07551.1 - 0.0057 15.4 0.5 2.7 6.6 0.1 3.2 1 1 3 4 4 4 1 Nup133 N terminal like GATase PF00117.23 ETO07551.1 - 0.0077 15.7 0.0 11 5.3 0.0 2.9 1 1 2 3 3 3 2 Glutamine amidotransferase class-I Phage_CI_repr PF07022.8 ETO07551.1 - 0.042 13.9 0.0 2.4 8.2 0.0 2.4 2 0 0 2 2 2 0 Bacteriophage CI repressor helix-turn-helix domain TFIIIC_delta PF12657.2 ETO07551.1 - 0.13 11.9 0.3 0.25 11.0 0.0 1.5 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term PD40 PF07676.7 ETO07551.1 - 0.17 11.5 0.4 2.5 7.8 0.0 2.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Kelch_6 PF13964.1 ETO07552.1 - 5.9e-08 32.5 3.6 0.015 15.4 0.0 4.6 4 1 1 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO07552.1 - 0.00087 19.0 0.2 0.0097 15.6 0.0 2.8 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO07552.1 - 0.00093 18.8 0.9 0.23 11.3 0.0 3.0 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 ETO07552.1 - 0.0034 17.5 0.0 0.055 13.6 0.0 2.8 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO07552.1 - 0.018 14.5 10.2 0.19 11.3 0.1 4.5 5 0 0 5 5 5 0 Kelch motif Kelch_5 PF13854.1 ETO07552.1 - 0.022 14.7 0.6 2.6 8.1 0.1 3.3 3 0 0 3 3 3 0 Kelch motif RepA_C PF04796.7 ETO07552.1 - 0.025 14.2 0.1 0.22 11.0 0.0 2.4 3 0 0 3 3 3 0 Plasmid encoded RepA protein F-box-like PF12937.2 ETO07553.1 - 0.00018 21.1 0.1 0.00035 20.2 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETO07553.1 - 0.078 12.6 2.1 0.13 11.9 0.1 2.2 2 0 0 2 2 2 0 F-box domain MoCo_carrier PF12694.2 ETO07553.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative molybdenum carrier WD40 PF00400.27 ETO07555.1 - 4e-24 83.5 16.4 3.8e-06 26.5 2.4 6.6 6 1 0 6 6 6 5 WD domain, G-beta repeat SMC_N PF02463.14 ETO07556.1 - 5.4e-26 91.2 0.0 7.9e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETO07556.1 - 0.0093 15.9 0.1 0.026 14.5 0.0 1.7 2 1 0 2 2 2 1 AAA domain WD40 PF00400.27 ETO07558.1 - 3.4e-60 197.8 24.5 1.2e-12 47.1 0.1 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO07558.1 - 2.4e-09 35.8 2.9 0.00071 17.8 0.1 4.0 3 1 0 3 3 3 3 Nucleoporin Nup120/160 Alpha-L-AF_C PF06964.7 ETO07558.1 - 0.11 12.2 0.0 0.44 10.2 0.0 2.0 2 0 0 2 2 2 0 Alpha-L-arabinofuranosidase C-terminus Kelch_6 PF13964.1 ETO07559.1 - 1.2e-06 28.3 0.7 0.005 16.9 0.1 4.4 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO07559.1 - 2.4e-05 24.0 0.4 0.059 13.1 0.0 3.4 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO07559.1 - 0.0023 17.4 1.5 0.0069 15.9 0.0 2.6 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO07559.1 - 0.084 12.6 6.7 0.5 10.2 0.1 4.3 5 1 0 5 5 5 0 Kelch motif Tir_receptor_C PF07489.6 ETO07560.1 - 0.0087 15.8 1.1 0.0087 15.8 0.7 1.9 2 0 0 2 2 2 1 Translocated intimin receptor (Tir) C-terminus CCDC-167 PF15188.1 ETO07560.1 - 0.15 12.0 3.2 0.32 10.9 2.2 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 PBP1_TM PF14812.1 ETO07560.1 - 0.27 11.5 5.2 0.16 12.3 1.9 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_L29e PF01779.12 ETO07560.1 - 0.72 9.7 8.9 0.26 11.1 2.7 2.8 3 0 0 3 3 3 0 Ribosomal L29e protein family tRNA_anti-codon PF01336.20 ETO07561.1 - 0.0048 16.7 0.2 0.015 15.1 0.0 2.0 2 1 0 2 2 2 1 OB-fold nucleic acid binding domain HTH_Tnp_1 PF01527.15 ETO07561.1 - 0.059 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Transposase Pinin_SDK_memA PF04696.8 ETO07562.1 - 0.00014 21.4 2.7 0.00014 21.4 1.9 1.7 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region Kelch_1 PF01344.20 ETO07563.1 - 4.7e-09 35.6 3.1 0.00092 18.7 0.1 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO07563.1 - 7.4e-07 29.0 4.3 0.057 13.6 0.0 5.1 5 1 0 5 5 5 1 Kelch motif Kelch_2 PF07646.10 ETO07563.1 - 7.7e-07 28.6 1.5 0.027 14.2 0.1 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO07563.1 - 0.09 12.7 8.7 1.3 9.0 0.1 4.7 6 0 0 6 6 6 0 Kelch motif Kelch_3 PF13415.1 ETO07563.1 - 0.37 11.0 2.8 14 5.9 0.0 3.7 4 1 0 4 4 4 0 Galactose oxidase, central domain WD40 PF00400.27 ETO07564.1 - 2.2e-12 46.3 13.3 3.2e-09 36.3 2.3 3.7 3 1 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO07564.1 - 0.0047 15.1 0.4 0.046 11.8 0.1 1.9 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Flavi_propep PF01570.12 ETO07565.1 - 0.36 10.6 3.6 0.41 10.4 2.0 1.6 1 1 0 1 1 1 0 Flavivirus polyprotein propeptide zf-4CXXC_R1 PF10497.4 ETO07566.1 - 0.039 14.0 0.3 0.047 13.8 0.2 1.1 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 KGK PF08872.5 ETO07566.1 - 0.12 12.5 1.4 0.15 12.2 1.0 1.1 1 0 0 1 1 1 0 KGK domain DUF2121 PF09894.4 ETO07567.1 - 0.17 11.1 2.9 0.8 8.9 0.2 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2121) DDRGK PF09756.4 ETO07568.1 - 0.37 10.1 22.6 0.4 10.0 15.7 1.0 1 0 0 1 1 1 0 DDRGK domain FAM60A PF15396.1 ETO07568.1 - 3.5 7.3 21.4 3.8 7.1 14.8 1.0 1 0 0 1 1 1 0 Protein Family FAM60A TMCO5 PF14992.1 ETO07568.1 - 5.3 6.0 14.8 5.6 6.0 10.3 1.0 1 0 0 1 1 1 0 TMCO5 family DUF3385 PF11865.3 ETO07568.1 - 9.9 6.0 6.5 11 5.8 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) TipAS PF07739.8 ETO07571.1 - 0.0048 17.2 0.4 0.35 11.1 0.0 2.3 2 0 0 2 2 2 1 TipAS antibiotic-recognition domain HlyC PF02794.11 ETO07571.1 - 0.058 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 RTX toxin acyltransferase family Swi3 PF07962.7 ETO07571.1 - 0.34 10.5 3.8 2.8 7.6 0.0 2.7 3 1 0 3 3 3 0 Replication Fork Protection Component Swi3 Plasmid_parti PF01672.11 ETO07571.1 - 1 9.8 5.4 0.44 11.0 0.6 2.7 2 1 2 4 4 4 0 Putative plasmid partition protein Leukemia_assc_2 PF15197.1 ETO07572.1 - 1.1 8.9 3.7 6.4 6.5 3.1 1.8 1 1 1 2 2 2 0 Leukemia-associated protein 2 WD40 PF00400.27 ETO07573.1 - 7.5e-10 38.3 0.1 2.8e-09 36.4 0.1 1.9 2 0 0 2 2 2 1 WD domain, G-beta repeat RHD3 PF05879.7 ETO07574.1 - 9.8e-06 23.7 13.1 6.3e-05 21.1 0.0 2.5 2 1 0 2 2 2 2 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.18 ETO07574.1 - 0.069 12.9 2.8 0.14 11.9 0.0 2.6 2 1 0 2 2 2 0 Dynamin family WD40 PF00400.27 ETO07575.1 - 4.7e-20 70.6 9.3 1.4e-09 37.4 0.4 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO07575.1 - 8e-05 20.9 2.0 0.0035 15.5 0.2 2.1 1 1 0 2 2 2 2 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO07575.1 - 0.037 13.3 3.1 0.055 12.7 2.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4221) DUF2559 PF10832.3 ETO07575.1 - 0.18 11.6 0.5 15 5.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2559) NST1 PF13945.1 ETO07579.1 - 1.2 9.2 5.6 1.2 9.1 1.4 2.0 2 0 0 2 2 2 0 Salt tolerance down-regulator DUF1754 PF08555.5 ETO07579.1 - 5.4 7.6 13.1 0.99 10.0 3.8 2.1 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) TPR_12 PF13424.1 ETO07580.1 - 1.3e-32 111.5 11.2 6.7e-18 64.4 0.3 3.3 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO07580.1 - 5.3e-11 42.0 11.4 0.00015 21.3 0.6 3.4 3 0 0 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETO07580.1 - 1.6e-10 40.1 16.0 0.0005 19.5 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO07580.1 - 3.5e-10 39.0 11.7 0.00075 19.2 0.1 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO07580.1 - 1e-09 37.4 3.8 0.0019 17.8 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO07580.1 - 1.5e-08 34.3 0.4 0.0019 18.0 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO07580.1 - 0.0098 15.6 15.9 1.2 9.1 0.1 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat MIT PF04212.13 ETO07580.1 - 0.015 15.1 7.1 0.12 12.3 0.4 3.1 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_17 PF13431.1 ETO07580.1 - 0.055 13.6 0.9 20 5.7 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETO07580.1 - 0.17 12.5 0.0 8.2 7.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Hom_end_hint PF05203.11 ETO07581.1 - 0.011 15.4 1.2 0.013 15.2 0.9 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint Ank_5 PF13857.1 ETO07581.1 - 0.055 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO07581.1 - 0.11 12.8 0.1 0.39 11.1 0.0 1.6 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO07581.1 - 0.12 12.8 0.1 0.31 11.6 0.0 1.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO07581.1 - 0.13 12.5 0.2 0.32 11.3 0.1 1.8 1 1 0 1 1 1 0 Ankyrin repeat Mucin PF01456.12 ETO07581.1 - 4 7.1 26.1 5.5 6.7 18.1 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein LRR_1 PF00560.28 ETO07583.1 - 6.6e-16 55.9 20.1 0.055 13.5 0.0 9.0 7 1 1 8 8 8 7 Leucine Rich Repeat LRR_4 PF12799.2 ETO07583.1 - 5e-15 54.7 29.3 1.7e-05 24.3 1.8 6.7 4 2 3 7 7 7 7 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 ETO07583.1 - 4.4e-13 47.1 23.0 0.29 11.4 0.1 9.3 9 0 0 9 9 9 6 Leucine rich repeat LRR_8 PF13855.1 ETO07583.1 - 8.9e-13 47.7 22.5 4.7e-06 26.2 2.5 5.2 3 2 1 4 4 4 4 Leucine rich repeat LRR_6 PF13516.1 ETO07583.1 - 5.6e-09 35.1 23.4 0.4 10.8 0.0 8.3 8 0 0 8 8 8 5 Leucine Rich repeat DUF3794 PF12673.2 ETO07584.1 - 0.004 17.2 0.9 0.0083 16.2 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3794) Kelch_6 PF13964.1 ETO07586.1 - 0.52 10.5 3.6 3.9 7.8 0.2 2.3 1 1 1 2 2 2 0 Kelch motif Kelch_2 PF07646.10 ETO07586.1 - 0.85 9.4 3.1 19 5.1 2.2 2.3 1 1 0 1 1 1 0 Kelch motif HD_5 PF13487.1 ETO07588.1 - 0.079 12.9 0.0 7.6 6.5 0.0 2.8 2 0 0 2 2 2 0 HD domain DLH PF01738.13 ETO07589.1 - 4.4e-06 26.1 0.0 7e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 ETO07589.1 - 0.001 18.8 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 ETO07589.1 - 0.0021 17.5 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.2 ETO07589.1 - 0.089 12.6 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Kelch_4 PF13418.1 ETO07590.1 - 4.4e-05 23.1 0.4 0.1 12.3 0.0 2.4 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO07590.1 - 0.00016 21.6 3.4 0.0059 16.7 0.5 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.20 ETO07590.1 - 0.0008 18.8 4.4 0.0019 17.6 1.2 2.3 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.10 ETO07590.1 - 0.0036 17.0 1.1 0.17 11.7 0.2 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.1 ETO07590.1 - 0.049 13.5 3.1 0.66 10.0 1.4 2.3 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.1 ETO07590.1 - 0.058 13.5 0.3 0.51 10.5 0.0 2.5 3 0 0 3 3 3 0 Galactose oxidase, central domain WD40 PF00400.27 ETO07592.1 - 7.4e-51 168.3 20.6 1.3e-10 40.7 0.2 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO07592.1 - 6.6e-07 27.8 1.7 0.062 11.4 0.1 3.7 2 2 1 3 3 3 3 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO07592.1 - 3e-05 24.2 1.7 3e-05 24.2 1.2 2.8 2 0 0 2 2 2 1 TRAF-type zinc finger BBS2_N PF14781.1 ETO07592.1 - 0.00022 20.8 0.4 0.0037 16.8 0.0 3.1 3 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, N-terminal eIF2A PF08662.6 ETO07592.1 - 0.00024 20.8 1.8 0.64 9.6 0.2 3.3 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Phage_holin_3 PF05106.7 ETO07592.1 - 0.15 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) BetaGal_dom4_5 PF13364.1 ETO07593.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain PDR_CDR PF06422.7 ETO07594.1 - 0.08 12.6 1.9 0.11 12.1 0.6 1.7 1 1 1 2 2 2 0 CDR ABC transporter CARD PF00619.16 ETO07595.1 - 0.032 14.0 0.2 0.051 13.4 0.2 1.2 1 0 0 1 1 1 0 Caspase recruitment domain WD40 PF00400.27 ETO07597.1 - 1.5e-09 37.3 1.1 7.4e-09 35.1 0.3 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO07597.1 - 0.011 13.9 0.2 0.017 13.2 0.0 1.4 2 0 0 2 2 2 0 Nucleoporin Nup120/160 DUF525 PF04379.9 ETO07597.1 - 0.03 14.2 0.6 0.053 13.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF525) HEAT_2 PF13646.1 ETO07598.1 - 3.8e-10 39.9 0.0 1.6e-08 34.7 0.0 2.7 2 1 0 2 2 2 1 HEAT repeats HEAT PF02985.17 ETO07598.1 - 9.9e-10 37.6 0.1 0.14 12.3 0.0 4.5 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 ETO07598.1 - 0.00062 20.1 0.0 1.3 9.5 0.0 3.3 3 1 0 3 3 3 1 HEAT-like repeat TIP120 PF08623.5 ETO07598.1 - 0.0014 18.2 6.4 0.13 11.7 2.5 2.5 1 1 1 2 2 2 2 TATA-binding protein interacting (TIP20) DUF4411 PF14367.1 ETO07598.1 - 0.019 14.6 0.9 0.032 13.9 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) DYW_deaminase PF14432.1 ETO07598.1 - 0.066 13.2 2.0 0.12 12.4 1.4 1.4 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases CDC45 PF02724.9 ETO07600.1 - 0.2 9.6 29.2 0.3 9.0 20.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Prog_receptor PF02161.10 ETO07600.1 - 3.2 6.4 8.6 3.9 6.1 5.9 1.2 1 0 0 1 1 1 0 Progesterone receptor DUF3102 PF11300.3 ETO07602.1 - 0.095 12.7 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3102) F-box PF00646.28 ETO07604.1 - 0.00055 19.5 0.4 0.0011 18.5 0.1 1.6 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 ETO07604.1 - 0.065 12.9 0.2 0.22 11.3 0.1 1.8 2 0 0 2 2 2 0 F-box-like Mac PF12464.3 ETO07604.1 - 0.094 12.7 0.7 0.19 11.7 0.5 1.4 1 0 0 1 1 1 0 Maltose acetyltransferase ComC PF03047.9 ETO07604.1 - 0.27 10.7 1.5 0.55 9.7 1.0 1.5 1 0 0 1 1 1 0 COMC family Exo_endo_phos_2 PF14529.1 ETO07605.1 - 1.8e-20 72.7 3.6 1.8e-20 72.7 2.5 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Daxx PF03344.10 ETO07606.1 - 1.3 7.4 17.3 1.6 7.0 12.0 1.2 1 0 0 1 1 1 0 Daxx Family TPR_11 PF13414.1 ETO07607.1 - 4.8e-10 38.9 6.8 2.6e-05 23.7 2.8 2.8 1 1 1 2 2 2 2 TPR repeat TPR_16 PF13432.1 ETO07607.1 - 1e-05 26.0 0.0 0.034 14.8 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO07607.1 - 1.3e-05 24.7 14.3 0.032 14.1 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO07607.1 - 0.0011 18.4 11.1 0.26 10.9 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO07607.1 - 0.0044 17.3 8.4 0.22 11.8 0.0 3.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO07607.1 - 0.0056 17.2 0.1 1.3 9.8 0.0 3.3 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO07607.1 - 0.007 16.2 13.6 0.17 11.8 1.7 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat Reo_sigmaC PF04582.7 ETO07607.1 - 0.011 14.9 1.1 0.018 14.2 0.8 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TPR_7 PF13176.1 ETO07607.1 - 0.011 15.4 3.8 6.6 6.7 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO07607.1 - 3.2 8.3 0.0 3.2 8.3 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat Phage_GPO PF05929.6 ETO07607.1 - 8.7 5.5 13.7 14 4.8 9.5 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase FeS PF04060.8 ETO07609.1 - 0.36 10.4 3.4 4.9 6.8 0.2 2.5 2 0 0 2 2 2 0 Putative Fe-S cluster DUF2457 PF10446.4 ETO07609.1 - 0.99 8.0 4.6 1.4 7.5 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Aminotran_5 PF00266.14 ETO07610.1 - 3.1e-12 45.9 0.1 4.2e-12 45.5 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V RXT2_N PF08595.6 ETO07610.1 - 0.016 14.9 3.9 0.68 9.7 0.6 2.1 1 1 1 2 2 2 0 RXT2-like, N-terminal ABC_tran PF00005.22 ETO07611.1 - 7e-06 26.3 0.0 6.7e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA_5 PF07728.9 ETO07611.1 - 0.00031 20.4 0.0 0.00092 18.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 ETO07611.1 - 0.00033 20.4 0.5 0.0097 15.6 0.4 2.6 1 1 0 1 1 1 1 Archaeal ATPase Miro PF08477.8 ETO07611.1 - 0.00034 21.0 0.1 0.0021 18.5 0.0 2.3 3 1 1 4 4 4 1 Miro-like protein DUF258 PF03193.11 ETO07611.1 - 0.00057 19.0 0.0 0.0012 18.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA PF00004.24 ETO07611.1 - 0.00065 19.9 0.0 0.0021 18.2 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 ETO07611.1 - 0.0017 18.0 0.0 0.29 10.7 0.0 2.6 2 1 0 2 2 2 1 NACHT domain AAA_14 PF13173.1 ETO07611.1 - 0.0032 17.3 0.0 0.012 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETO07611.1 - 0.0038 17.3 0.0 0.017 15.2 0.0 2.1 3 0 0 3 3 3 1 AAA domain Lectin_N PF03954.9 ETO07611.1 - 0.017 14.5 0.0 0.054 12.8 0.0 1.8 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF3086 PF11285.3 ETO07611.1 - 0.018 13.8 0.5 1.3 7.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) Sigma54_activ_2 PF14532.1 ETO07611.1 - 0.022 14.7 0.1 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.17 ETO07611.1 - 0.042 14.0 0.1 0.25 11.5 0.0 2.3 2 1 0 2 2 2 0 RNA helicase DndB PF14072.1 ETO07611.1 - 0.048 12.8 0.5 0.098 11.7 0.3 1.5 1 1 0 1 1 1 0 DNA-sulfur modification-associated PduV-EutP PF10662.4 ETO07611.1 - 0.06 12.8 0.2 0.4 10.1 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 ETO07611.1 - 0.062 13.2 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.13 ETO07611.1 - 0.096 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase 2OG-FeII_Oxy_2 PF13532.1 ETO07613.1 - 4.7e-13 49.4 0.0 6e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ERAP1_C PF11838.3 ETO07615.1 - 9.3e-22 77.6 0.0 1.3e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 ERAP1-like C-terminal domain WD40 PF00400.27 ETO07616.1 - 6.4e-20 70.2 5.3 2.3e-10 39.9 0.0 5.4 4 1 0 4 4 4 4 WD domain, G-beta repeat zf-TRAF PF02176.13 ETO07616.1 - 0.00094 19.5 5.0 0.00094 19.5 3.5 2.6 2 0 0 2 2 2 1 TRAF-type zinc finger Complex1_LYR_1 PF13232.1 ETO07617.1 - 0.055 13.6 0.8 1.2 9.4 0.1 2.7 2 0 0 2 2 2 0 Complex1_LYR-like Complex1_LYR PF05347.10 ETO07617.1 - 0.39 10.5 6.2 0.2 11.4 0.6 2.7 2 0 0 2 2 2 0 Complex 1 protein (LYR family) zf-RING_5 PF14634.1 ETO07618.1 - 0.00045 19.8 6.2 0.00077 19.1 4.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 ETO07618.1 - 0.00089 19.0 7.3 0.0014 18.3 5.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 ETO07618.1 - 0.0033 17.0 7.3 0.0062 16.1 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO07618.1 - 0.0055 16.3 5.1 0.0096 15.5 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO07618.1 - 0.0073 16.3 7.0 0.012 15.6 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.19 ETO07618.1 - 0.033 14.0 3.6 0.033 14.0 2.5 2.1 2 0 0 2 2 2 0 B-box zinc finger Zn_Tnp_IS91 PF14319.1 ETO07618.1 - 0.074 12.5 1.5 0.16 11.5 1.0 1.5 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-RING_UBOX PF13445.1 ETO07618.1 - 0.091 12.4 8.5 0.24 11.1 5.5 2.1 2 0 0 2 2 2 0 RING-type zinc-finger EamA PF00892.15 ETO07619.1 - 0.00026 21.0 14.0 0.04 13.9 5.2 3.0 2 1 1 3 3 3 2 EamA-like transporter family DUF3317 PF11779.3 ETO07619.1 - 0.17 11.3 2.8 0.26 10.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3317) EmrE PF13536.1 ETO07619.1 - 0.17 12.0 12.4 0.2 11.8 3.1 2.9 1 1 1 3 3 3 0 Multidrug resistance efflux transporter Arif-1 PF06770.6 ETO07619.1 - 0.28 10.5 5.5 1.5 8.1 1.6 2.2 2 0 0 2 2 2 0 Actin-rearrangement-inducing factor (Arif-1) Borrelia_P13 PF05628.7 ETO07619.1 - 0.35 10.6 4.0 0.77 9.5 0.3 2.4 1 1 1 2 2 2 0 Borrelia membrane protein P13 BioY PF02632.9 ETO07619.1 - 4.5 6.9 9.3 6.5 6.3 0.3 2.5 1 1 1 2 2 2 0 BioY family His_Phos_1 PF00300.17 ETO07620.1 - 1.5e-20 73.8 0.0 5.3e-20 72.1 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Piwi PF02171.12 ETO07620.1 - 0.019 13.9 0.1 0.033 13.1 0.1 1.4 1 0 0 1 1 1 0 Piwi domain His_Phos_2 PF00328.17 ETO07620.1 - 0.057 12.7 0.2 0.1 11.9 0.1 1.7 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Brr6_like_C_C PF10104.4 ETO07624.1 - 0.0069 15.9 0.4 0.0069 15.9 0.3 1.9 2 0 0 2 2 2 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF2393 PF09624.5 ETO07624.1 - 0.02 14.4 1.6 0.02 14.4 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) zf-LITAF-like PF10601.4 ETO07624.1 - 0.021 14.6 1.7 0.064 13.1 0.6 2.2 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain zf-H2C2_2 PF13465.1 ETO07624.1 - 0.022 15.0 0.1 3.6 8.0 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.1 ETO07624.1 - 0.098 13.0 0.8 0.098 13.0 0.5 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4496 PF14908.1 ETO07624.1 - 0.1 12.4 3.8 0.079 12.8 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4496) Disulph_isomer PF06491.6 ETO07625.1 - 0.022 14.6 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 Disulphide isomerase Piwi PF02171.12 ETO07626.1 - 4.3e-38 130.9 1.8 8.1e-38 130.0 0.3 1.9 1 1 1 2 2 2 1 Piwi domain PAZ PF02170.17 ETO07626.1 - 2.3 7.5 17.5 0.011 15.0 2.8 3.4 3 1 0 3 3 3 0 PAZ domain WD40 PF00400.27 ETO07628.1 - 1e-13 50.5 3.6 2.9e-06 26.9 0.2 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 ETO07628.1 - 0.022 14.5 0.1 0.15 11.8 0.0 2.3 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region DAHP_synth_1 PF00793.15 ETO07628.1 - 0.052 12.2 0.0 0.086 11.5 0.0 1.2 1 0 0 1 1 1 0 DAHP synthetase I family PH_9 PF15410.1 ETO07629.1 - 0.0049 17.0 0.6 4.3 7.5 0.0 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain Ycf1 PF05758.7 ETO07630.1 - 0.0014 16.4 0.9 0.0014 16.4 0.6 2.0 2 0 0 2 2 2 1 Ycf1 IncA PF04156.9 ETO07630.1 - 0.0032 17.0 3.7 0.0032 17.0 2.5 1.7 3 0 0 3 3 3 1 IncA protein FAM176 PF14851.1 ETO07630.1 - 0.0074 15.9 1.0 0.0074 15.9 0.7 2.1 2 0 0 2 2 2 1 FAM176 family Spore_coat_CotO PF14153.1 ETO07630.1 - 0.0081 15.6 7.0 0.0081 15.6 4.8 2.2 2 0 0 2 2 2 1 Spore coat protein CotO DUF818 PF05677.7 ETO07630.1 - 0.028 13.1 0.0 0.069 11.8 0.0 1.6 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) EIIBC-GUT_N PF03612.9 ETO07630.1 - 0.05 13.2 0.5 0.05 13.2 0.3 2.0 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4199 PF13858.1 ETO07630.1 - 0.24 11.2 1.0 0.82 9.5 0.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) UPF0242 PF06785.6 ETO07630.1 - 0.25 9.9 6.5 0.39 9.3 4.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) EDR1 PF14381.1 ETO07630.1 - 0.36 10.3 3.3 0.13 11.8 0.1 1.7 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 TRAP_alpha PF03896.11 ETO07630.1 - 0.66 8.9 9.1 0.063 12.2 1.1 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit SID-1_RNA_chan PF13965.1 ETO07630.1 - 0.87 7.6 7.6 0.22 9.6 2.7 1.7 1 1 1 2 2 2 0 dsRNA-gated channel SID-1 GAGA_bind PF06217.7 ETO07630.1 - 1.3 8.9 13.1 3.1 7.6 3.1 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family AAA_23 PF13476.1 ETO07630.1 - 1.7 8.9 17.9 1.5 9.1 11.5 1.4 1 1 0 1 1 1 0 AAA domain OAD_gamma PF04277.8 ETO07630.1 - 7.1 7.0 5.5 4.1 7.8 0.1 2.6 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Cytomega_UL84 PF06284.6 ETO07630.1 - 7.4 4.8 8.8 1.4 7.1 1.6 2.0 2 0 0 2 2 2 0 Cytomegalovirus UL84 protein Zip PF02535.17 ETO07630.1 - 8.9 5.2 6.5 32 3.3 4.4 2.0 1 1 0 1 1 1 0 ZIP Zinc transporter DUF4191 PF13829.1 ETO07631.1 - 0.0081 15.3 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4191) PIG-H PF10181.4 ETO07631.1 - 0.054 13.1 0.1 0.099 12.2 0.1 1.3 1 0 0 1 1 1 0 GPI-GlcNAc transferase complex, PIG-H component Tetraspannin PF00335.15 ETO07631.1 - 1.6 7.9 12.3 3.5 6.8 8.5 1.6 1 1 0 1 1 1 0 Tetraspanin family Pkinase PF00069.20 ETO07632.1 - 2.1e-41 141.8 4.4 2.5e-20 72.7 1.5 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO07632.1 - 1.8e-19 69.8 3.5 2.6e-10 39.8 1.3 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase PDDEXK_2 PF12784.2 ETO07633.1 - 2.7e-52 177.2 0.5 3.8e-52 176.7 0.3 1.2 1 0 0 1 1 1 1 PD-(D/E)XK nuclease family transposase Yae1_N PF09811.4 ETO07633.1 - 0.00092 18.6 4.4 0.0022 17.4 3.0 1.6 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Transposase_31 PF04754.7 ETO07633.1 - 0.0055 16.0 0.3 0.018 14.3 0.1 2.0 2 1 0 2 2 2 1 Putative transposase, YhgA-like DUF91 PF01939.11 ETO07633.1 - 0.057 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF91 Ank_2 PF12796.2 ETO07634.1 - 4.1e-09 36.6 0.4 1e-07 32.1 0.1 2.7 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO07634.1 - 2.2e-05 24.0 0.0 0.034 13.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 ETO07634.1 - 3.2e-05 24.2 0.1 0.00016 22.0 0.1 2.2 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO07634.1 - 0.014 15.6 0.0 0.14 12.4 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO07634.1 - 0.044 14.0 0.2 9.4 6.8 0.0 3.8 3 1 0 3 3 3 0 Ankyrin repeat SpoIIIAH PF12685.2 ETO07635.1 - 0.64 9.4 17.6 0.81 9.1 12.2 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Apt1 PF10351.4 ETO07635.1 - 2.2 7.0 16.5 2.7 6.7 11.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SprA-related PF12118.3 ETO07635.1 - 3 7.0 20.1 3.7 6.7 13.9 1.1 1 0 0 1 1 1 0 SprA-related family Neur_chan_memb PF02932.11 ETO07635.1 - 8.2 6.2 11.0 13 5.6 7.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DNA_pol_A_exo1 PF01612.15 ETO07636.1 - 7.9e-20 71.0 0.4 1.6e-19 70.0 0.3 1.6 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 ETO07636.1 - 1.9e-09 37.6 0.3 1.2e-08 35.1 0.2 2.2 2 0 0 2 2 2 1 PMC2NT (NUC016) domain WD40 PF00400.27 ETO07637.1 - 7.7e-59 193.6 22.4 1.1e-10 40.9 0.1 7.3 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO07637.1 - 2.3e-13 49.1 3.7 7.9e-06 24.2 0.1 4.5 2 1 1 3 3 3 3 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO07637.1 - 0.011 15.4 0.9 0.62 9.7 0.1 3.4 2 2 2 4 4 4 0 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 ETO07637.1 - 0.021 13.6 8.4 1.4 7.6 0.0 4.4 2 1 0 2 2 2 0 Nup133 N terminal like WD40 PF00400.27 ETO07638.1 - 1.5e-06 27.8 0.2 9.4e-05 22.1 0.1 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat WD40 PF00400.27 ETO07639.1 - 4e-27 93.0 16.5 6.9e-09 35.2 1.6 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat zf-TRAF PF02176.13 ETO07639.1 - 1.4e-07 31.7 3.1 1.4e-07 31.7 2.1 2.8 2 1 1 3 3 3 1 TRAF-type zinc finger Nup160 PF11715.3 ETO07639.1 - 0.00015 20.0 2.0 0.017 13.2 0.0 2.9 1 1 1 2 2 2 2 Nucleoporin Nup120/160 RXT2_N PF08595.6 ETO07639.1 - 0.016 14.9 5.1 0.04 13.7 2.8 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal V_ATPase_I PF01496.14 ETO07639.1 - 0.65 7.7 8.3 0.91 7.2 5.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Bap31 PF05529.7 ETO07639.1 - 0.66 9.4 12.7 0.053 12.9 4.4 2.1 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like zf-C3HC4_4 PF15227.1 ETO07639.1 - 1.5 8.7 6.1 4 7.4 0.6 3.3 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING DUF342 PF03961.8 ETO07639.1 - 2.2 6.6 13.9 0.097 11.0 5.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF342) YaaC PF14175.1 ETO07639.1 - 9.5 5.0 14.1 1.6 7.5 6.0 2.0 2 0 0 2 2 2 0 YaaC-like Protein tRNA_int_endo PF01974.12 ETO07641.1 - 0.014 15.1 1.3 0.02 14.6 0.1 1.9 2 0 0 2 2 2 0 tRNA intron endonuclease, catalytic C-terminal domain Herpes_UL36 PF03586.8 ETO07641.1 - 0.046 12.7 0.0 0.094 11.7 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein DUF1796 PF08795.5 ETO07641.1 - 0.085 12.4 0.6 0.51 9.9 0.1 1.9 1 1 1 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) Poxvirus_B22R PF04395.7 ETO07641.1 - 0.14 11.6 3.2 0.46 9.9 0.2 2.2 2 0 0 2 2 2 0 Poxvirus B22R protein Tubulin PF00091.20 ETO07642.1 - 1.2e-57 195.2 0.0 1.5e-57 194.9 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Gly_kinase PF02595.10 ETO07642.1 - 0.033 12.9 0.0 0.044 12.4 0.0 1.1 1 0 0 1 1 1 0 Glycerate kinase family Tubulin_2 PF13809.1 ETO07642.1 - 0.18 10.7 1.7 0.3 9.9 0.9 1.5 1 1 1 2 2 2 0 Tubulin like Kelch_6 PF13964.1 ETO07643.1 - 9.8e-05 22.3 0.4 0.043 14.0 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO07643.1 - 0.036 13.8 0.5 4.6 7.1 0.0 3.4 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.1 ETO07643.1 - 0.083 12.8 0.1 4.2 7.4 0.0 3.2 3 0 0 3 3 3 0 Kelch motif Kelch_1 PF01344.20 ETO07643.1 - 1.9 8.1 5.0 1.5 8.4 0.0 3.0 4 0 0 4 4 4 0 Kelch motif WD40 PF00400.27 ETO07644.1 - 9.1e-59 193.3 25.1 1.1e-11 44.0 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO07644.1 - 3.1e-11 42.1 1.6 0.0047 15.1 0.1 4.9 2 1 2 5 5 5 5 Nucleoporin Nup120/160 WD40 PF00400.27 ETO07645.1 - 3.3e-12 45.7 5.7 5.7e-05 22.8 1.0 3.3 2 1 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO07645.1 - 0.028 12.5 0.8 1.7 6.6 0.1 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 ICAM_N PF03921.9 ETO07645.1 - 0.066 12.6 3.0 1.9 8.0 0.1 2.2 1 1 1 2 2 2 0 Intercellular adhesion molecule (ICAM), N-terminal domain A_deaminase PF00962.17 ETO07646.1 - 3.3e-16 59.1 0.0 3.8e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase NACHT PF05729.7 ETO07647.1 - 5.5e-11 42.4 0.0 2.2e-10 40.4 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETO07647.1 - 0.001 19.1 0.0 0.0023 17.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.4 ETO07647.1 - 0.0014 17.6 0.6 0.0045 16.0 0.0 2.1 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 ETO07647.1 - 0.005 16.5 0.0 0.0084 15.8 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain G-alpha PF00503.15 ETO07647.1 - 0.0052 15.5 0.8 0.0063 15.2 0.6 1.1 1 0 0 1 1 1 1 G-protein alpha subunit AAA_18 PF13238.1 ETO07647.1 - 0.0075 16.5 0.7 0.0091 16.3 0.0 1.5 2 0 0 2 2 2 1 AAA domain DAP3 PF10236.4 ETO07647.1 - 0.0085 15.0 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 NB-ARC PF00931.17 ETO07647.1 - 0.011 14.5 0.0 0.016 14.0 0.0 1.3 1 1 0 1 1 1 0 NB-ARC domain Torsin PF06309.6 ETO07647.1 - 0.017 14.9 0.0 0.033 14.0 0.0 1.4 2 0 0 2 2 2 0 Torsin RNA_helicase PF00910.17 ETO07647.1 - 0.031 14.4 0.1 0.046 13.9 0.1 1.3 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 ETO07647.1 - 0.062 13.4 0.0 0.12 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.14 ETO07647.1 - 0.078 12.1 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Angiomotin_C PF12240.3 ETO07648.1 - 0.028 13.9 0.5 0.031 13.7 0.4 1.2 1 0 0 1 1 1 0 Angiomotin C terminal DUF1344 PF07076.6 ETO07648.1 - 0.051 13.1 0.1 0.08 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) Med30 PF11315.3 ETO07648.1 - 0.095 12.8 0.9 0.11 12.5 0.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 30 UPF0180 PF03698.8 ETO07649.1 - 0.0074 16.1 0.1 0.016 14.9 0.1 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0180) DZR PF12773.2 ETO07649.1 - 0.099 12.4 2.4 0.27 11.0 1.7 1.8 1 0 0 1 1 1 0 Double zinc ribbon DUF349 PF03993.7 ETO07649.1 - 0.14 12.3 5.1 0.54 10.4 0.9 2.8 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) DUF3641 PF12345.3 ETO07649.1 - 0.16 11.8 5.6 0.38 10.6 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3641) Rpr2 PF04032.11 ETO07649.1 - 2.1 8.2 11.5 0.55 10.1 5.0 2.3 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-CCHC PF00098.18 ETO07649.1 - 7.6 6.6 10.7 0.17 11.8 1.1 2.4 2 0 0 2 2 2 0 Zinc knuckle FERM_C PF09380.5 ETO07650.1 - 0.0045 17.1 0.4 0.012 15.7 0.3 1.8 1 0 0 1 1 1 1 FERM C-terminal PH-like domain SAP PF02037.22 ETO07650.1 - 0.009 15.4 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 1 SAP domain DUF1443 PF07280.6 ETO07651.1 - 0.12 11.9 2.2 2.4 7.8 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1443) WD40 PF00400.27 ETO07652.1 - 6.4e-47 155.8 7.8 5.7e-12 45.0 0.1 4.7 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO07652.1 - 1.5e-08 33.2 0.7 0.0029 15.7 0.0 3.2 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO07652.1 - 0.0091 14.7 4.9 0.5 9.0 2.0 2.6 1 1 1 2 2 2 2 Nup133 N terminal like RVP PF00077.15 ETO07653.1 - 2e-06 27.6 0.1 1e-05 25.3 0.0 2.2 2 0 0 2 2 2 1 Retroviral aspartyl protease zf-CCHC PF00098.18 ETO07653.1 - 0.00026 20.7 7.3 0.00066 19.4 5.1 1.7 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.1 ETO07653.1 - 0.029 14.8 0.0 0.069 13.6 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease PLDc_2 PF13091.1 ETO07656.1 - 1.4e-09 37.7 1.2 0.00014 21.6 0.0 2.5 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.17 ETO07656.1 - 1.1e-08 34.6 2.3 0.00093 18.9 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif DUF1565 PF07602.6 ETO07656.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) Ribosomal_L34e PF01199.13 ETO07657.1 - 1e-12 48.1 1.5 1e-12 48.1 1.1 2.7 2 1 1 3 3 3 1 Ribosomal protein L34e Stm1_N PF09598.5 ETO07659.1 - 0.053 14.2 0.7 0.098 13.3 0.5 1.4 1 0 0 1 1 1 0 Stm1 Peptidase_S49_N PF08496.5 ETO07660.1 - 3.6 7.3 8.1 0.84 9.4 0.1 2.7 3 0 0 3 3 3 0 Peptidase family S49 N-terminal Clathrin PF00637.15 ETO07662.1 - 3e-21 75.5 12.5 1.8e-10 40.5 0.5 2.8 2 0 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.3 ETO07662.1 - 3.7e-08 33.0 1.2 3.7e-08 33.0 0.8 3.7 4 0 0 4 4 4 1 Vacuolar protein sorting protein 11 C terminal zf-RING_5 PF14634.1 ETO07662.1 - 0.034 13.8 9.4 0.093 12.4 6.5 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.2 ETO07662.1 - 0.17 11.9 5.2 0.41 10.8 3.6 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger CCDC-167 PF15188.1 ETO07662.1 - 0.18 11.7 6.7 4.7 7.2 0.1 2.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 zf-RING_2 PF13639.1 ETO07662.1 - 0.18 11.6 11.4 0.21 11.4 6.5 2.2 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.1 ETO07662.1 - 0.41 10.7 11.9 0.3 11.1 6.6 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DivIC PF04977.10 ETO07662.1 - 2.1 7.8 11.5 0.38 10.2 4.2 2.5 2 0 0 2 2 2 0 Septum formation initiator zf-C3HC4 PF00097.20 ETO07662.1 - 5 6.8 13.3 4.3 7.0 7.6 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FdsD PF11390.3 ETO07664.1 - 0.091 12.8 0.1 0.58 10.2 0.1 2.2 2 0 0 2 2 2 0 NADH-dependant formate dehydrogenase delta subunit FdsD MutS_V PF00488.16 ETO07665.1 - 8.9e-80 267.4 0.0 1.5e-79 266.7 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 ETO07665.1 - 1.3e-33 116.5 1.4 2.3e-33 115.7 1.0 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 ETO07665.1 - 6.4e-18 64.8 0.1 1.9e-17 63.2 0.0 1.8 1 1 0 1 1 1 1 MutS domain I MutS_II PF05188.12 ETO07665.1 - 3.1e-09 37.0 0.0 3.1e-09 37.0 0.0 3.0 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.13 ETO07665.1 - 1.3e-06 28.5 6.3 1.3e-06 28.5 4.4 2.5 2 0 0 2 2 2 1 MutS family domain IV Kelch_4 PF13418.1 ETO07666.1 - 3.5e-08 33.0 0.1 0.0039 16.9 0.0 2.4 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO07666.1 - 3.7e-06 26.4 0.5 0.00016 21.2 0.2 2.3 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.20 ETO07666.1 - 9.8e-06 25.0 7.1 0.00018 20.9 1.2 2.6 2 1 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 ETO07666.1 - 0.028 14.6 0.0 0.16 12.2 0.0 2.1 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO07666.1 - 0.031 14.4 2.0 0.073 13.2 0.2 2.4 2 1 1 3 3 3 0 Kelch motif PTR2 PF00854.16 ETO07667.1 - 2.8e-15 55.9 0.8 3.1e-15 55.8 0.5 1.0 1 0 0 1 1 1 1 POT family DUF3810 PF12725.2 ETO07667.1 - 2.8 6.7 10.6 1.5 7.6 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) DUF1768 PF08719.6 ETO07671.1 - 0.023 14.4 1.5 0.024 14.3 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1768) PDGF PF00341.12 ETO07671.1 - 0.068 13.2 7.9 0.14 12.2 5.5 1.6 1 1 0 1 1 1 0 PDGF/VEGF domain Astro_capsid PF03115.9 ETO07672.1 - 9.8 4.2 12.2 12 4.0 8.5 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor SprA-related PF12118.3 ETO07673.1 - 1.3 8.3 17.7 2.7 7.2 12.3 1.5 1 0 0 1 1 1 0 SprA-related family WD40 PF00400.27 ETO07674.1 - 2.2e-18 65.3 3.0 1.6e-10 40.4 0.1 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO07674.1 - 7.3e-05 21.0 0.2 0.00015 20.1 0.0 1.4 1 1 0 1 1 1 1 Nucleoporin Nup120/160 SRI PF08236.6 ETO07676.1 - 0.00067 19.5 0.1 0.0011 18.8 0.1 1.4 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain GerPC PF10737.4 ETO07676.1 - 0.045 13.5 1.2 0.063 13.0 0.9 1.3 1 0 0 1 1 1 0 Spore germination protein GerPC Cullin_binding PF03556.10 ETO07677.1 - 0.036 14.2 0.3 0.036 14.2 0.2 5.2 6 1 1 7 7 7 0 Cullin binding CAP_GLY PF01302.20 ETO07678.1 - 0.00039 20.0 0.0 0.0012 18.4 0.0 1.8 2 0 0 2 2 2 1 CAP-Gly domain DUF1003 PF06210.6 ETO07678.1 - 0.046 13.6 1.5 7.5 6.5 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1003) GRP PF07172.6 ETO07678.1 - 0.064 13.7 0.5 0.4 11.1 0.1 2.1 2 0 0 2 2 2 0 Glycine rich protein family Amidohydro_5 PF13594.1 ETO07679.1 - 8.6e-11 41.5 0.2 1.3e-10 40.9 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 ETO07679.1 - 0.087 12.0 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase family DUF643 PF04867.7 ETO07679.1 - 0.74 10.2 7.1 1.5 9.2 4.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF643) Glyco_hydro_47 PF01532.15 ETO07681.1 - 8.9e-31 107.0 0.0 1e-30 106.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 BT1 PF03092.11 ETO07681.1 - 0.089 11.4 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 BT1 family DUF4131 PF13567.1 ETO07682.1 - 1.1 8.6 8.4 0.17 11.3 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Amidohydro_5 PF13594.1 ETO07683.1 - 4.7e-10 39.1 0.3 1.1e-09 37.8 0.2 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 ETO07683.1 - 2.9e-09 37.3 0.0 7.1e-06 26.2 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 ETO07683.1 - 8.4e-09 35.1 0.0 2.3e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.15 ETO07683.1 - 6.4e-06 26.0 1.1 0.0086 15.7 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase family TLD PF07534.11 ETO07684.1 - 5.1e-05 23.2 1.5 0.00012 22.1 0.0 2.4 2 0 0 2 2 2 1 TLD Colicin_im PF03857.8 ETO07684.1 - 0.0086 15.8 0.1 0.019 14.7 0.1 1.5 1 0 0 1 1 1 1 Colicin immunity protein LRR_5 PF13306.1 ETO07687.1 - 0.039 13.6 1.4 0.077 12.7 0.7 1.6 1 1 0 1 1 1 0 Leucine rich repeats (6 copies) SID-1_RNA_chan PF13965.1 ETO07689.1 - 0.0018 16.5 1.4 0.0019 16.4 1.0 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 CBP4 PF07960.6 ETO07689.1 - 0.3 10.7 4.4 0.44 10.1 3.1 1.2 1 0 0 1 1 1 0 CBP4 Chromo PF00385.19 ETO07690.1 - 3.9e-14 52.0 4.5 8.5e-07 28.5 0.1 2.8 2 1 1 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain SNF2_N PF00176.18 ETO07691.1 - 6.5e-46 156.4 0.4 9e-46 156.0 0.3 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 ETO07691.1 - 2.6e-06 27.3 0.1 1.8e-05 24.6 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 ETO07691.1 - 5.9e-05 22.6 0.0 0.00029 20.3 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 ETO07691.1 - 0.00049 20.2 0.0 0.0035 17.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 ETO07691.1 - 0.0092 14.9 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DEAD_2 PF06733.10 ETO07691.1 - 0.24 10.8 0.0 0.24 10.8 0.0 1.9 2 1 0 2 2 2 0 DEAD_2 Cyclin_N PF00134.18 ETO07692.1 - 0.0011 18.5 0.6 1.4 8.4 0.2 2.5 2 1 0 2 2 2 2 Cyclin, N-terminal domain Lipoprotein_19 PF13617.1 ETO07692.1 - 0.018 14.6 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 YnbE-like lipoprotein Amnionless PF14828.1 ETO07693.1 - 0.00024 19.7 0.0 0.00035 19.1 0.0 1.2 1 0 0 1 1 1 1 Amnionless Peptidase_M56 PF05569.6 ETO07693.1 - 0.0034 16.3 0.0 0.0052 15.7 0.0 1.3 1 0 0 1 1 1 1 BlaR1 peptidase M56 TMEM51 PF15345.1 ETO07693.1 - 0.0036 17.0 0.3 0.0055 16.4 0.2 1.3 1 0 0 1 1 1 1 Transmembrane protein 51 IncA PF04156.9 ETO07693.1 - 0.0052 16.3 0.0 0.0071 15.9 0.0 1.1 1 0 0 1 1 1 1 IncA protein Vpu PF00558.14 ETO07693.1 - 0.0057 16.1 0.1 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Vpu protein TMEM154 PF15102.1 ETO07693.1 - 0.01 15.5 0.2 0.022 14.4 0.0 1.6 2 0 0 2 2 2 0 TMEM154 protein family DUF912 PF06024.7 ETO07693.1 - 0.014 15.4 0.0 0.042 13.8 0.0 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Plasmodium_Vir PF05795.6 ETO07693.1 - 0.019 14.2 0.1 0.019 14.2 0.1 1.7 1 1 1 2 2 2 0 Plasmodium vivax Vir protein DUF2069 PF09842.4 ETO07693.1 - 0.022 14.7 0.3 0.043 13.7 0.2 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2069) DUF4448 PF14610.1 ETO07693.1 - 0.047 13.1 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF3365 PF11845.3 ETO07693.1 - 0.058 13.2 0.2 2.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3365) Herpes_gE PF02480.11 ETO07693.1 - 0.068 11.4 0.0 0.1 10.8 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Adeno_E3_14_5 PF04834.7 ETO07693.1 - 0.092 13.1 0.6 0.64 10.4 0.0 2.4 2 0 0 2 2 2 0 Early E3 14.5 kDa protein DUF2681 PF10883.3 ETO07693.1 - 0.16 12.2 0.7 0.32 11.2 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) WD40 PF00400.27 ETO07694.1 - 9.9e-63 205.9 31.5 6.9e-12 44.7 0.3 7.1 8 0 0 8 8 8 6 WD domain, G-beta repeat zf-TRAF PF02176.13 ETO07694.1 - 1.1e-06 28.8 2.1 5e-06 26.7 1.5 2.2 1 0 0 1 1 1 1 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 ETO07694.1 - 0.41 10.7 5.3 0.55 10.2 0.1 3.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF4407 PF14362.1 ETO07694.1 - 4.9 6.0 14.0 7.2 5.4 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_C14 PF00656.17 ETO07695.1 - 7.2e-08 32.4 2.6 2.1e-05 24.3 0.1 2.7 2 1 1 3 3 3 2 Caspase domain NDUF_B5 PF09781.4 ETO07695.1 - 0.049 12.9 0.1 0.093 11.9 0.1 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit VOMI PF03762.12 ETO07696.1 - 0.0051 16.7 0.0 0.012 15.5 0.0 1.7 1 1 0 1 1 1 1 Vitelline membrane outer layer protein I (VOMI) BAF1_ABF1 PF04684.8 ETO07696.1 - 6.1 5.5 6.7 9.5 4.9 4.6 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4519 PF15012.1 ETO07697.1 - 1.4 8.8 0.0 1.4 8.8 0.0 4.9 5 1 0 5 5 5 0 Domain of unknown function (DUF4519) Jnk-SapK_ap_N PF09744.4 ETO07697.1 - 8.6 6.3 16.1 0.21 11.5 3.3 2.4 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 GRP PF07172.6 ETO07698.1 - 0.14 12.6 0.7 0.25 11.8 0.5 1.3 1 0 0 1 1 1 0 Glycine rich protein family RVT_1 PF00078.22 ETO07699.1 - 3.3e-31 108.3 0.5 6.1e-31 107.4 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 ETO07699.1 - 3.9e-14 52.2 0.2 9.2e-14 51.0 0.1 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 ETO07699.1 - 6e-07 29.6 0.0 1.1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF573 PF04504.9 ETO07699.1 - 0.061 13.6 2.6 0.087 13.1 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF573 DUF1002 PF06207.6 ETO07700.1 - 0.038 13.3 1.1 0.053 12.8 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) Condensin2nSMC PF12422.3 ETO07700.1 - 0.039 13.7 1.5 0.062 13.0 1.0 1.4 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit Herpes_UL45 PF05473.7 ETO07700.1 - 0.11 11.9 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 UL45 protein PUB PF09409.5 ETO07700.1 - 0.61 9.8 8.8 0.065 12.9 1.5 2.8 3 1 0 3 3 3 0 PUB domain GAGA_bind PF06217.7 ETO07701.1 - 0.76 9.6 15.3 1.1 9.1 10.6 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Utp14 PF04615.8 ETO07701.1 - 0.92 7.5 30.0 1.2 7.1 20.8 1.0 1 0 0 1 1 1 0 Utp14 protein DUF1675 PF07897.6 ETO07701.1 - 0.95 9.2 22.8 1.3 8.7 15.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF1183 PF06682.7 ETO07701.1 - 2 7.9 10.4 2.7 7.4 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) MMR_HSR1 PF01926.18 ETO07703.1 - 5.7e-19 68.1 0.1 3.3e-18 65.7 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase KH_dom-like PF14714.1 ETO07703.1 - 9.1e-15 54.3 1.7 2.3e-14 53.0 1.2 1.8 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.13 ETO07703.1 - 4.8e-09 35.6 0.0 3.4e-05 23.1 0.0 2.6 2 1 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 ETO07703.1 - 1.2e-07 31.4 0.4 4.8e-05 22.8 0.1 3.3 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain Miro PF08477.8 ETO07703.1 - 0.00027 21.4 0.0 0.029 14.8 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 ETO07703.1 - 0.0012 18.7 0.1 0.0012 18.7 0.1 3.9 3 1 0 3 3 3 1 Dynamin family Ras PF00071.17 ETO07703.1 - 0.0067 15.8 0.0 1.6 8.1 0.0 2.8 2 1 0 2 2 2 1 Ras family ArgK PF03308.11 ETO07703.1 - 0.053 12.2 0.0 0.41 9.3 0.0 2.1 2 0 0 2 2 2 0 ArgK protein CDC45 PF02724.9 ETO07703.1 - 5.7 4.8 15.9 2.3 6.1 8.4 2.0 2 0 0 2 2 2 0 CDC45-like protein VWA_2 PF13519.1 ETO07704.1 - 4.1e-07 30.2 0.1 6.3e-07 29.6 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 ETO07704.1 - 0.0091 15.7 0.1 0.017 14.8 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain HSP90 PF00183.13 ETO07705.1 - 7.3e-96 321.6 22.6 2.7e-93 313.1 9.1 2.0 1 1 1 2 2 2 2 Hsp90 protein Syntaxin PF00804.20 ETO07705.1 - 7.9 6.7 9.1 0.088 12.9 0.4 2.1 3 0 0 3 3 3 0 Syntaxin Kinesin PF00225.18 ETO07708.1 - 3.4e-54 183.7 2.5 3.4e-54 183.7 1.7 1.6 2 0 0 2 2 2 1 Kinesin motor domain EF-hand_1 PF00036.27 ETO07708.1 - 0.0019 17.3 1.8 0.0026 16.9 0.2 2.2 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 ETO07708.1 - 0.0037 17.3 0.3 0.02 15.0 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO07708.1 - 0.0071 16.1 0.1 0.034 14.0 0.0 2.2 1 0 0 1 1 1 1 EF-hand domain EzrA PF06160.7 ETO07708.1 - 0.0076 14.4 9.2 0.0061 14.8 4.8 1.8 2 0 0 2 2 2 1 Septation ring formation regulator, EzrA COG5 PF10392.4 ETO07708.1 - 0.24 11.3 7.2 0.1 12.5 2.9 1.9 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Peptidase_M1 PF01433.15 ETO07709.1 - 9.6e-07 28.2 0.3 1e-06 28.1 0.2 1.0 1 0 0 1 1 1 1 Peptidase family M1 DUF2636 PF11120.3 ETO07710.1 - 2 7.9 8.1 1.2 8.6 0.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2636) LRRC37AB_C PF14914.1 ETO07711.1 - 0.23 10.8 5.5 0.22 10.9 2.1 2.2 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain SLA_LP_auto_ag PF05889.8 ETO07712.1 - 3.9e-82 275.8 0.6 5.1e-82 275.4 0.4 1.1 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Peroxin-13_N PF04088.8 ETO07712.1 - 0.13 12.2 1.2 0.21 11.5 0.8 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region WD40 PF00400.27 ETO07713.1 - 4.7e-30 102.3 9.6 3.1e-11 42.7 0.1 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO07713.1 - 3.1e-08 32.2 2.0 0.0026 15.9 0.0 3.5 1 1 3 4 4 4 3 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO07713.1 - 0.00046 20.5 0.4 0.00046 20.5 0.3 2.2 2 0 0 2 2 2 1 TRAF-type zinc finger IncA PF04156.9 ETO07713.1 - 1.8 8.1 7.8 3.2 7.3 5.4 1.4 1 0 0 1 1 1 0 IncA protein NACHT PF05729.7 ETO07714.1 - 1.4e-11 44.3 0.0 2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETO07714.1 - 1.5e-06 28.4 0.0 2.8e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETO07714.1 - 2.1e-06 28.0 0.2 2.1e-06 28.0 0.1 1.9 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.15 ETO07714.1 - 0.00013 20.7 2.1 0.0002 20.2 1.4 1.3 1 0 0 1 1 1 1 G-protein alpha subunit AAA_17 PF13207.1 ETO07714.1 - 0.0011 19.7 0.7 0.0022 18.7 0.1 1.9 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 ETO07714.1 - 0.0073 15.5 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 ETO07714.1 - 0.0076 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.7 ETO07714.1 - 0.0097 15.0 0.1 0.018 14.1 0.1 1.5 1 1 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 ETO07714.1 - 0.012 15.5 0.1 0.19 11.7 0.0 2.1 1 1 1 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 ETO07714.1 - 0.013 15.7 0.1 0.056 13.6 0.1 2.2 1 1 1 2 2 2 0 RNA helicase Myosin_head PF00063.16 ETO07714.1 - 0.015 13.3 0.2 0.015 13.3 0.1 1.8 1 1 1 2 2 2 0 Myosin head (motor domain) UPF0079 PF02367.12 ETO07714.1 - 0.016 14.8 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 ETO07714.1 - 0.016 15.4 0.0 0.028 14.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 ETO07714.1 - 0.018 15.3 0.3 0.03 14.5 0.2 1.4 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 ETO07714.1 - 0.018 14.7 0.0 0.033 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 ETO07714.1 - 0.022 14.2 0.0 0.044 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DAP3 PF10236.4 ETO07714.1 - 0.056 12.3 0.2 0.14 11.0 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 T2SE PF00437.15 ETO07714.1 - 0.079 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activat PF00158.21 ETO07714.1 - 0.089 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.1 ETO07714.1 - 0.098 12.0 0.0 11 5.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 ETO07714.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain EF-hand_1 PF00036.27 ETO07714.1 - 0.68 9.3 3.2 0.38 10.1 0.6 1.9 2 0 0 2 2 2 0 EF hand Ammonium_transp PF00909.16 ETO07715.1 - 1.4e-53 181.8 9.3 1.6e-53 181.5 6.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF1614 PF07758.6 ETO07715.1 - 0.036 13.8 5.4 0.1 12.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1614) Herpes_pp38 PF04846.8 ETO07715.1 - 0.1 11.9 2.3 12 5.3 0.0 3.7 3 0 0 3 3 3 0 Herpesvirus pp38 phosphoprotein SieB PF14163.1 ETO07720.1 - 0.016 14.8 0.1 0.039 13.5 0.0 1.6 1 0 0 1 1 1 0 Superinfection exclusion protein B DUF912 PF06024.7 ETO07720.1 - 0.21 11.6 2.5 8 6.5 1.8 2.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Ribosomal_L30_N PF08079.7 ETO07721.1 - 0.12 12.4 2.6 0.22 11.5 1.8 1.5 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain NigD PF12667.2 ETO07723.1 - 0.0036 17.1 0.2 0.005 16.6 0.1 1.3 1 0 0 1 1 1 1 NigD-like protein HIRAN PF08797.6 ETO07723.1 - 0.015 15.1 0.0 0.03 14.2 0.0 1.5 2 0 0 2 2 2 0 HIRAN domain Peptidase_M43 PF05572.8 ETO07723.1 - 0.061 12.9 0.7 0.1 12.1 0.1 1.6 2 0 0 2 2 2 0 Pregnancy-associated plasma protein-A Beta_helix PF13229.1 ETO07724.1 - 3.7e-07 30.0 8.2 3.7e-07 30.0 5.7 2.8 2 1 1 3 3 3 2 Right handed beta helix region DUF1565 PF07602.6 ETO07724.1 - 0.0028 16.8 1.6 0.0055 15.8 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1565) SnoaL_4 PF13577.1 ETO07726.1 - 9.2e-16 57.9 0.0 1e-15 57.7 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.2 ETO07726.1 - 0.0026 18.1 0.0 0.0035 17.7 0.0 1.3 1 1 0 1 1 1 1 SnoaL-like domain DUF4471 PF14740.1 ETO07726.1 - 0.0079 15.4 0.1 0.011 14.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) NTF2 PF02136.15 ETO07726.1 - 0.011 16.0 0.0 0.017 15.4 0.0 1.3 1 1 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain Lig_chan-Glu_bd PF10613.4 ETO07726.1 - 0.074 13.0 0.0 0.25 11.3 0.0 1.9 2 0 0 2 2 2 0 Ligated ion channel L-glutamate- and glycine-binding site Spc24 PF08286.6 ETO07727.1 - 0.0012 18.4 5.3 0.023 14.3 0.5 2.7 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 DUF972 PF06156.8 ETO07727.1 - 0.025 14.9 3.8 0.7 10.2 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) WD40 PF00400.27 ETO07728.1 - 7.9e-62 203.0 16.8 7.6e-12 44.6 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO07728.1 - 6.8e-07 27.8 7.5 0.24 9.4 0.2 4.7 2 1 1 4 4 4 4 Nucleoporin Nup120/160 DPPIV_N PF00930.16 ETO07728.1 - 0.0013 17.3 0.3 1.7 7.1 0.0 3.6 1 1 2 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.7 ETO07728.1 - 0.0026 17.3 0.3 8.2 6.2 0.0 3.7 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO07728.1 - 0.011 15.2 0.1 0.1 12.0 0.0 2.2 1 1 1 2 2 2 0 PQQ-like domain Str_synth PF03088.11 ETO07728.1 - 0.044 13.8 0.1 5.9 6.9 0.0 3.2 4 0 0 4 4 4 0 Strictosidine synthase OST3_OST6 PF04756.8 ETO07731.1 - 0.00025 20.6 2.8 0.00025 20.6 1.9 1.7 2 0 0 2 2 2 1 OST3 / OST6 family DUF3088 PF11287.3 ETO07731.1 - 0.057 12.8 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3088) RicinB_lectin_2 PF14200.1 ETO07732.1 - 0.0035 17.6 2.5 0.091 13.1 0.2 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Peptidase_C78 PF07910.8 ETO07732.1 - 0.0035 16.4 0.8 0.0049 16.0 0.1 1.6 2 0 0 2 2 2 1 Peptidase family C78 HEAT_2 PF13646.1 ETO07733.1 - 4e-13 49.4 0.0 0.015 15.5 0.0 5.9 3 1 1 5 5 5 4 HEAT repeats Ank_3 PF13606.1 ETO07733.1 - 2.1e-09 36.7 0.4 1.4e-05 24.8 0.0 4.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 ETO07733.1 - 2.6e-08 34.1 0.3 1.7e-07 31.5 0.2 2.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO07733.1 - 7.1e-07 29.4 0.2 7.1e-07 29.4 0.2 3.1 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) HEAT PF02985.17 ETO07733.1 - 7.3e-07 28.7 0.0 5.3 7.3 0.0 7.2 8 0 0 8 8 8 2 HEAT repeat Ank PF00023.25 ETO07733.1 - 2.2e-06 27.1 0.1 3e-05 23.6 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 ETO07733.1 - 2.4e-06 27.5 0.8 5.1e-05 23.3 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Cnd1 PF12717.2 ETO07733.1 - 9.9e-06 25.5 40.1 0.0014 18.5 2.8 5.6 1 1 3 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 ETO07733.1 - 0.024 15.1 0.0 28 5.3 0.0 5.3 7 0 0 7 7 7 0 HEAT-like repeat DUF2435 PF10363.4 ETO07733.1 - 0.11 12.4 7.2 0.96 9.3 0.1 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2435) Peptidase_C1 PF00112.18 ETO07734.1 - 3.3e-25 89.2 0.8 3.6e-25 89.1 0.5 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 ETO07734.1 - 0.022 13.3 1.2 0.029 12.9 0.8 1.1 1 0 0 1 1 1 0 Peptidase C1-like family Peptidase_C1 PF00112.18 ETO07735.1 - 8.6e-14 51.9 4.3 5e-06 26.5 0.0 2.6 2 1 0 2 2 2 2 Papain family cysteine protease WD40 PF00400.27 ETO07736.1 - 5.3e-11 41.9 1.1 5.8e-09 35.4 0.0 2.4 2 1 0 2 2 2 2 WD domain, G-beta repeat SprB PF13573.1 ETO07736.1 - 0.66 9.6 3.7 6.3 6.4 0.1 2.3 2 0 0 2 2 2 0 SprB repeat AIG1 PF04548.11 ETO07737.1 - 3.8e-12 45.7 0.0 5.3e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 AIG1 family AAA PF00004.24 ETO07737.1 - 0.086 13.0 0.0 12 6.0 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Kelch_5 PF13854.1 ETO07738.1 - 0.0099 15.8 0.1 3.4 7.7 0.0 2.9 2 0 0 2 2 2 2 Kelch motif WD40 PF00400.27 ETO07739.1 - 1.3e-46 154.8 9.4 9.5e-12 44.3 0.1 6.2 5 1 1 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO07739.1 - 1.3e-05 23.5 1.2 0.055 11.5 0.1 2.8 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO07739.1 - 0.0041 16.5 0.2 0.14 11.6 0.1 2.2 1 1 1 2 2 2 2 PQQ-like domain PD40 PF07676.7 ETO07739.1 - 0.0066 16.0 5.6 20 4.9 0.1 5.1 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO07739.1 - 0.012 13.9 0.2 1.5 7.0 0.1 2.3 1 1 0 2 2 2 0 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO07739.1 - 0.027 13.5 0.1 9.9 5.1 0.0 3.3 2 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 ETO07739.1 - 0.34 10.2 6.2 6.7 6.1 0.0 3.8 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Pyr_redox PF00070.22 ETO07740.1 - 0.00033 20.9 0.2 0.012 16.0 0.0 3.0 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase DASH_Ask1 PF08655.5 ETO07740.1 - 0.036 13.8 0.8 0.1 12.4 0.4 1.9 1 1 1 2 2 2 0 DASH complex subunit Ask1 DUF3115 PF11312.3 ETO07740.1 - 0.13 11.1 0.1 0.24 10.1 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3115) WD40 PF00400.27 ETO07741.1 - 7.9e-43 142.8 18.1 1e-11 44.2 1.8 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO07741.1 - 5.4e-12 44.6 6.5 3e-06 25.6 0.2 5.0 2 1 3 5 5 5 3 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO07741.1 - 1.2e-07 31.9 1.9 5.6e-07 29.8 1.3 2.2 1 0 0 1 1 1 1 TRAF-type zinc finger RXT2_N PF08595.6 ETO07741.1 - 0.0033 17.2 5.3 0.0067 16.2 3.2 1.8 2 0 0 2 2 2 1 RXT2-like, N-terminal Cytochrom_D1 PF02239.11 ETO07741.1 - 0.011 14.1 0.5 0.13 10.5 0.1 2.4 2 1 0 2 2 2 0 Cytochrome D1 heme domain CR6_interact PF10147.4 ETO07741.1 - 0.17 11.1 8.9 0.39 10.0 6.2 1.5 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 zf-C3HC4_4 PF15227.1 ETO07741.1 - 0.6 10.0 5.1 2.7 7.9 0.3 3.1 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING IncA PF04156.9 ETO07741.1 - 7.6 6.0 10.7 14 5.2 7.4 1.3 1 0 0 1 1 1 0 IncA protein WD40 PF00400.27 ETO07742.1 - 5.9e-116 374.6 41.3 1.2e-10 40.8 0.0 14.4 15 0 0 15 15 15 12 WD domain, G-beta repeat NACHT PF05729.7 ETO07742.1 - 1.5e-09 37.7 0.0 3.3e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.7 ETO07742.1 - 6.9e-09 35.1 13.5 2.8 7.6 0.0 10.4 11 0 0 11 11 11 1 WD40-like Beta Propeller Repeat Pentapeptide PF00805.17 ETO07742.1 - 7.8e-07 28.2 0.8 1.7e-06 27.0 0.5 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) AAA_18 PF13238.1 ETO07742.1 - 6.1e-06 26.5 0.0 3.2e-05 24.2 0.0 2.2 1 0 0 1 1 1 1 AAA domain Pentapeptide_4 PF13599.1 ETO07742.1 - 3.8e-05 23.3 1.1 0.0001 22.0 0.7 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 ETO07742.1 - 0.00069 19.4 0.3 0.0018 18.1 0.2 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA_22 PF13401.1 ETO07742.1 - 0.0014 18.8 0.0 0.0036 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO07742.1 - 0.0033 18.2 0.4 0.026 15.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain DUF4123 PF13503.1 ETO07742.1 - 0.015 15.2 0.0 0.04 13.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4123) AAA_29 PF13555.1 ETO07742.1 - 0.039 13.4 0.0 0.74 9.3 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Gmad1 PF10647.4 ETO07742.1 - 0.064 12.6 0.0 4.3 6.6 0.0 3.3 4 0 0 4 4 4 0 Lipoprotein LpqB beta-propeller domain FtsK_SpoIIIE PF01580.13 ETO07742.1 - 0.088 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Glyco_transf_29 PF00777.13 ETO07743.1 - 0.046 12.8 0.1 0.068 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 29 (sialyltransferase) DUF2663 PF10864.3 ETO07743.1 - 0.6 10.3 4.7 0.64 10.2 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2663) DUF2236 PF09995.4 ETO07744.1 - 6.2e-15 55.1 0.0 1.4e-07 31.0 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2236) RGS PF00615.14 ETO07745.1 - 3e-06 27.3 1.1 5.3e-06 26.5 0.8 1.8 1 1 0 1 1 1 1 Regulator of G protein signaling domain WD40 PF00400.27 ETO07746.1 - 2.5e-57 188.8 22.0 1.9e-11 43.3 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO07746.1 - 3.6e-14 51.8 3.1 0.078 11.0 0.1 5.7 4 2 2 6 6 6 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO07746.1 - 0.0043 15.8 8.2 1.9 7.1 0.0 4.5 3 2 1 4 4 4 3 Nup133 N terminal like PQQ_2 PF13360.1 ETO07746.1 - 0.077 12.4 0.1 12 5.2 0.0 2.5 2 0 0 2 2 2 0 PQQ-like domain SAM_2 PF07647.12 ETO07747.1 - 0.075 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) CUB PF00431.15 ETO07748.1 - 0.13 12.3 4.7 0.16 12.0 1.1 2.1 1 1 0 2 2 2 0 CUB domain WD40 PF00400.27 ETO07750.1 - 1.4e-13 50.1 2.8 2e-10 40.1 0.2 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO07750.1 - 0.00012 20.3 0.1 0.00015 20.0 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 SID-1_RNA_chan PF13965.1 ETO07750.1 - 0.022 12.9 2.3 0.029 12.5 1.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF3810 PF12725.2 ETO07750.1 - 0.11 11.3 3.6 0.057 12.3 1.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) Selenoprotein_S PF06936.6 ETO07750.1 - 0.38 10.2 2.4 0.52 9.8 1.6 1.3 1 1 0 1 1 1 0 Selenoprotein S (SelS) DUF641 PF04859.7 ETO07750.1 - 1.2 8.9 7.1 2.2 8.0 4.9 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) WD40 PF00400.27 ETO07752.1 - 2.3e-61 201.6 25.5 7.9e-11 41.4 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO07752.1 - 2.4e-13 49.0 9.1 0.0021 16.2 0.2 5.5 2 2 3 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO07752.1 - 1.8e-06 26.9 14.7 0.02 13.6 5.2 5.3 2 1 1 4 4 4 4 Nup133 N terminal like DUF2452 PF10504.4 ETO07753.1 - 0.009 15.2 0.1 0.012 14.9 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2452) ApoLp-III PF07464.6 ETO07753.1 - 0.055 13.4 0.5 0.075 13.0 0.4 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) MitMem_reg PF13012.1 ETO07753.1 - 0.06 13.4 0.5 0.094 12.7 0.3 1.4 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function DUF1009 PF06230.6 ETO07753.1 - 0.063 12.6 0.0 0.085 12.2 0.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1009) KIP1 PF07765.7 ETO07753.1 - 0.07 12.9 0.3 0.2 11.5 0.1 1.7 1 1 1 2 2 2 0 KIP1-like protein DUF421 PF04239.7 ETO07753.1 - 0.074 12.5 0.2 0.096 12.2 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF421) Inos-1-P_synth PF01658.12 ETO07753.1 - 0.11 12.3 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Kelch_1 PF01344.20 ETO07754.1 - 2.3e-08 33.4 0.7 3.6e-07 29.6 0.2 2.8 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO07754.1 - 2.3e-07 30.3 0.3 0.0011 18.5 0.0 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO07754.1 - 1.3e-05 25.1 2.6 0.00091 19.3 0.3 3.3 2 1 1 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETO07754.1 - 0.00014 21.5 1.6 0.015 15.0 0.0 3.1 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO07754.1 - 0.016 15.1 1.6 0.22 11.5 0.6 2.9 3 0 0 3 3 3 0 Kelch motif Serinc PF03348.10 ETO07756.1 - 6.6e-15 54.7 22.1 1.3e-14 53.8 15.4 1.4 1 0 0 1 1 1 1 Serine incorporator (Serinc) BACK PF07707.10 ETO07757.1 - 7.8e-11 41.7 1.7 1.1e-06 28.4 0.5 2.1 1 1 1 2 2 2 2 BTB And C-terminal Kelch DnaI_N PF07319.6 ETO07757.1 - 0.021 15.0 0.1 0.032 14.4 0.1 1.3 1 0 0 1 1 1 0 Primosomal protein DnaI N-terminus BTB PF00651.26 ETO07758.1 - 0.036 14.0 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain HSP70 PF00012.15 ETO07759.1 - 0.0025 15.8 3.8 0.0034 15.3 2.7 1.2 1 0 0 1 1 1 1 Hsp70 protein SAM_2 PF07647.12 ETO07759.1 - 0.023 14.5 0.6 21 5.0 0.0 3.7 4 0 0 4 4 4 0 SAM domain (Sterile alpha motif) DUF2072 PF09845.4 ETO07759.1 - 0.071 13.0 6.3 0.12 12.3 3.9 1.7 1 1 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) TINF2_N PF14973.1 ETO07759.1 - 0.22 11.6 10.2 9.9 6.2 6.1 3.3 2 1 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus PTPlike_phytase PF14566.1 ETO07759.1 - 0.27 11.2 4.6 0.64 10.0 3.2 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate SAM_1 PF00536.25 ETO07759.1 - 0.3 11.2 2.3 6.7 6.9 0.0 3.5 4 0 0 4 4 4 0 SAM domain (Sterile alpha motif) DDHD PF02862.12 ETO07759.1 - 0.83 9.4 5.9 1.1 8.9 4.1 1.2 1 0 0 1 1 1 0 DDHD domain DUF3355 PF11835.3 ETO07759.1 - 0.85 9.4 5.6 0.6 9.8 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3355) LMBR1 PF04791.11 ETO07759.1 - 1.4 7.3 3.9 1.9 6.9 2.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein KilA-N PF04383.8 ETO07759.1 - 4.1 7.0 6.6 1.7 8.2 0.0 2.8 2 1 0 2 2 2 0 KilA-N domain Kelch_6 PF13964.1 ETO07760.1 - 6.9e-05 22.8 0.6 0.0047 17.0 0.1 2.7 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.20 ETO07760.1 - 0.0028 17.1 3.0 0.43 10.1 0.6 2.9 2 1 0 2 2 2 2 Kelch motif Kelch_2 PF07646.10 ETO07760.1 - 0.084 12.6 3.5 4.2 7.3 2.0 3.3 2 1 0 2 2 2 0 Kelch motif WD40 PF00400.27 ETO07761.1 - 2.2e-23 81.2 7.8 1e-10 41.0 0.6 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO07761.1 - 1.3e-05 23.5 1.6 0.00015 20.0 0.1 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 BBS2_N PF14781.1 ETO07761.1 - 0.25 10.9 4.2 7.3 6.2 0.2 2.3 1 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal DUF1053 PF06327.9 ETO07762.1 - 0.035 14.4 0.6 0.043 14.1 0.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) DUF4248 PF14053.1 ETO07763.1 - 0.048 13.2 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) DUF3296 PF11726.3 ETO07764.1 - 0.0044 16.6 2.4 0.0055 16.2 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3296) Clathrin PF00637.15 ETO07765.1 - 1.6e-15 56.9 6.9 3e-09 36.5 1.5 2.7 1 1 1 2 2 2 2 Region in Clathrin and VPS Kelch_6 PF13964.1 ETO07766.1 - 4.3e-06 26.6 2.4 7.5 6.9 0.0 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 ETO07766.1 - 1.2e-05 24.7 6.9 0.0003 20.2 0.1 4.4 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.10 ETO07766.1 - 1.3e-05 24.7 2.1 0.035 13.8 0.0 4.6 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.1 ETO07766.1 - 8.2e-05 22.2 0.2 0.03 14.1 0.0 3.4 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO07766.1 - 0.044 13.9 0.1 0.96 9.7 0.0 3.1 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO07766.1 - 0.049 13.5 0.2 13 5.9 0.1 3.9 4 0 0 4 4 4 0 Kelch motif adh_short PF00106.20 ETO07767.1 - 3.6e-24 85.5 0.1 2.6e-23 82.7 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETO07767.1 - 1.6e-09 37.8 0.3 1.3e-08 34.9 0.2 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETO07767.1 - 2.9e-08 33.5 0.1 5.2e-07 29.5 0.0 2.1 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 ETO07767.1 - 4.9e-06 26.6 0.0 0.00037 20.5 0.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 ETO07767.1 - 0.00046 19.7 0.2 0.0021 17.5 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 ETO07767.1 - 0.015 14.5 0.0 0.17 11.1 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family DUF1959 PF09218.5 ETO07767.1 - 0.073 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1959) RhoGEF PF00621.15 ETO07768.1 - 0.2 11.5 5.3 0.22 11.3 3.7 1.1 1 0 0 1 1 1 0 RhoGEF domain AA_permease_2 PF13520.1 ETO07769.1 - 5.3e-36 124.0 21.8 5.3e-36 124.0 15.1 1.9 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.16 ETO07769.1 - 1.8e-19 69.4 25.7 3.9e-19 68.3 17.8 1.6 1 1 0 1 1 1 1 Amino acid permease Peptidase_C14 PF00656.17 ETO07771.1 - 1.5e-05 24.8 0.2 2.6e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Caspase domain UL11 PF11094.3 ETO07771.1 - 0.1 12.4 0.1 0.27 11.0 0.1 1.7 1 0 0 1 1 1 0 Membrane-associated tegument protein UCH PF00443.24 ETO07771.1 - 1 8.3 4.4 1.7 7.7 3.1 1.6 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 ETO07772.1 - 0.00013 21.3 0.9 0.00022 20.5 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin family Synaptobrevin PF00957.16 ETO07774.1 - 0.063 12.8 0.7 0.063 12.8 0.5 2.4 2 0 0 2 2 2 0 Synaptobrevin WD40 PF00400.27 ETO07775.1 - 2.6e-25 87.3 11.0 2.1e-09 36.9 0.0 4.2 3 1 1 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO07775.1 - 1e-06 27.2 0.0 0.012 13.7 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO07775.1 - 0.041 12.6 1.0 0.29 9.8 0.1 2.0 1 1 1 2 2 2 0 Nup133 N terminal like HOOK PF05622.7 ETO07776.1 - 0.00067 17.6 14.6 0.00073 17.4 10.1 1.1 1 0 0 1 1 1 1 HOOK protein DUF1664 PF07889.7 ETO07776.1 - 0.01 15.6 15.0 0.17 11.7 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF1644 PF07800.7 ETO07776.1 - 0.012 15.4 1.0 0.012 15.4 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) PolyA_pol PF01743.15 ETO07776.1 - 0.014 15.5 3.2 0.028 14.6 2.2 1.5 1 0 0 1 1 1 0 Poly A polymerase head domain Phage_GP20 PF06810.6 ETO07776.1 - 0.058 12.8 26.8 0.056 12.8 10.1 2.9 2 2 0 2 2 2 0 Phage minor structural protein GP20 Toprim PF01751.17 ETO07776.1 - 0.74 9.8 5.8 3.3 7.7 1.6 2.4 1 1 1 2 2 2 0 Toprim domain Apolipoprotein PF01442.13 ETO07776.1 - 0.82 9.1 12.3 8.8 5.7 8.7 2.1 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain V_ATPase_I PF01496.14 ETO07776.1 - 0.87 7.3 15.6 0.055 11.3 2.1 2.2 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 ETO07776.1 - 1.4 9.3 16.1 2.3 8.6 2.4 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF972) DASH_Dad3 PF08656.5 ETO07776.1 - 2.8 7.7 9.1 64 3.3 6.3 2.6 1 1 0 1 1 1 0 DASH complex subunit Dad3 NPV_P10 PF05531.7 ETO07776.1 - 5.5 7.3 16.2 0.39 11.0 1.8 2.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 ETO07776.1 - 7.9 6.2 13.5 3.8e+02 0.8 9.3 2.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TnpV PF14198.1 ETO07776.1 - 8 6.3 9.9 4.8 7.1 0.4 2.6 2 1 1 3 3 3 0 Transposon-encoded protein TnpV DUF4407 PF14362.1 ETO07776.1 - 9.7 5.0 9.8 70 2.2 6.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) HycH PF07450.6 ETO07778.1 - 0.078 13.0 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH RRM_6 PF14259.1 ETO07779.1 - 1.8e-22 79.0 0.2 3.8e-10 39.5 0.0 3.8 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO07779.1 - 8.2e-15 54.2 0.2 2.7e-08 33.3 0.0 3.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO07779.1 - 2.6e-06 27.1 0.0 0.054 13.3 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Exo_endo_phos PF03372.18 ETO07780.1 - 1.9e-09 37.8 0.1 2.6e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Somatomedin_B PF01033.12 ETO07780.1 - 4.5e-05 23.3 23.8 4.5e-05 23.3 16.5 3.6 2 1 1 3 3 3 2 Somatomedin B domain Exo_endo_phos_2 PF14529.1 ETO07780.1 - 0.00012 21.6 0.3 0.00032 20.2 0.2 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DAGAT PF03982.8 ETO07781.1 - 7.2e-36 123.3 0.0 7.9e-36 123.2 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DUF4137 PF13593.1 ETO07782.1 - 9.6e-63 212.1 30.5 3.2e-32 111.8 8.8 3.1 2 1 0 2 2 2 2 SBF-like CPA transporter family (DUF4137) Myc_target_1 PF15179.1 ETO07782.1 - 0.91 9.0 6.7 1.2 8.6 0.0 3.1 3 0 0 3 3 3 0 Myc target protein 1 Baculo_E56 PF04639.7 ETO07784.1 - 0.041 12.5 0.2 0.05 12.2 0.1 1.1 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope Tom37_C PF11801.3 ETO07784.1 - 0.046 13.5 0.4 0.053 13.3 0.3 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain TraH_2 PF06871.6 ETO07784.1 - 0.049 13.0 0.2 0.056 12.8 0.1 1.1 1 0 0 1 1 1 0 TraH_2 IRF PF00605.12 ETO07784.1 - 0.075 12.8 0.8 0.12 12.1 0.6 1.3 1 0 0 1 1 1 0 Interferon regulatory factor transcription factor RXT2_N PF08595.6 ETO07785.1 - 0.22 11.2 17.3 0.1 12.3 2.3 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal BTV_NS2 PF04514.7 ETO07785.1 - 0.36 9.6 8.0 0.17 10.7 0.1 2.1 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 CENP-B_dimeris PF09026.5 ETO07785.1 - 0.57 10.4 10.7 0.58 10.4 2.3 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain FAM176 PF14851.1 ETO07785.1 - 0.73 9.5 6.1 2.4 7.8 0.1 2.2 2 0 0 2 2 2 0 FAM176 family DUF4611 PF15387.1 ETO07785.1 - 0.95 9.6 14.6 0.64 10.1 2.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF1863 PF08937.6 ETO07785.1 - 1.1 9.2 12.8 3 7.8 3.5 2.3 2 0 0 2 2 2 0 MTH538 TIR-like domain (DUF1863) PBP1_TM PF14812.1 ETO07785.1 - 1.2 9.5 16.4 0.13 12.5 2.7 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SIP1 PF04938.7 ETO07785.1 - 2.1 7.6 4.7 2.2 7.5 1.1 1.9 2 0 0 2 2 2 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) Secretin_N_2 PF07655.8 ETO07785.1 - 4.4 7.7 24.4 1.3 9.4 10.6 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain Bd3614_N PF14442.1 ETO07785.1 - 4.5 7.2 6.7 0.24 11.3 1.0 1.5 2 0 0 2 2 2 0 Bd3614-like deaminase N-terminal Nucleoplasmin PF03066.10 ETO07785.1 - 5.6 6.4 12.4 2.7 7.5 3.9 2.1 2 0 0 2 2 2 0 Nucleoplasmin Sigma70_ner PF04546.8 ETO07785.1 - 8.2 5.9 8.0 3.4 7.2 1.5 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region NRDE-2 PF08424.5 ETO07785.1 - 9.5 4.9 12.4 0.68 8.7 0.2 2.1 2 0 0 2 2 2 0 NRDE-2, necessary for RNA interference Eapp_C PF10238.4 ETO07785.1 - 9.7 6.0 23.5 10 6.0 3.1 2.5 2 0 0 2 2 2 0 E2F-associated phosphoprotein SOBP PF15279.1 ETO07787.1 - 0.33 11.2 9.8 0.51 10.6 6.8 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2392 PF10288.4 ETO07787.1 - 0.4 11.0 7.0 1.3 9.4 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2392) WD40 PF00400.27 ETO07788.1 - 2.5e-75 245.8 8.8 1.1e-13 50.5 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO07788.1 - 1.1e-08 33.6 6.9 0.013 13.6 0.0 5.1 1 1 2 5 5 5 4 Nucleoporin Nup120/160 DPPIV_N PF00930.16 ETO07788.1 - 1.9e-06 26.7 1.1 0.0029 16.2 0.4 3.2 2 1 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF727 PF05303.7 ETO07788.1 - 4.8e-05 23.1 0.7 1.1 9.1 0.0 3.9 3 1 0 3 3 3 1 Protein of unknown function (DUF727) PQQ_2 PF13360.1 ETO07788.1 - 0.00019 20.9 0.5 0.38 10.1 0.0 3.1 2 1 0 3 3 3 1 PQQ-like domain PD40 PF07676.7 ETO07788.1 - 0.00071 19.1 7.8 0.36 10.5 0.0 5.1 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat DUF3601 PF12208.3 ETO07788.1 - 0.0012 18.7 0.0 3.9 7.4 0.0 4.2 3 1 1 4 4 4 1 Domain of unknown function (DUF3601) Cytochrom_D1 PF02239.11 ETO07788.1 - 0.0046 15.3 0.3 5.2 5.2 0.0 3.2 1 1 0 2 2 2 2 Cytochrome D1 heme domain EnY2 PF10163.4 ETO07788.1 - 0.035 14.0 0.1 0.062 13.2 0.1 1.4 1 0 0 1 1 1 0 Transcription factor e(y)2 Cass2 PF14526.1 ETO07788.1 - 0.13 12.3 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 Integron-associated effector binding protein FA_desaturase PF00487.19 ETO07789.1 - 4.7e-13 49.1 7.2 5.3e-13 48.9 5.0 1.1 1 0 0 1 1 1 1 Fatty acid desaturase PSS PF03034.10 ETO07790.1 - 0.015 14.7 0.2 0.022 14.1 0.1 1.4 1 1 0 1 1 1 0 Phosphatidyl serine synthase zf-CW PF07496.10 ETO07791.1 - 5.9e-08 32.2 3.5 1.8e-07 30.7 2.4 1.9 1 0 0 1 1 1 1 CW-type Zinc Finger WD40 PF00400.27 ETO07792.1 - 0.0007 19.3 0.3 0.012 15.4 0.0 2.8 3 0 0 3 3 3 1 WD domain, G-beta repeat RL11D PF11088.3 ETO07792.1 - 0.0031 17.2 5.0 0.0092 15.7 2.3 2.1 2 0 0 2 2 2 1 Glycoprotein encoding membrane proteins RL5A and RL6 CbiA PF01656.18 ETO07795.1 - 3.9e-16 59.0 0.1 5.7e-16 58.4 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 ETO07795.1 - 6.5e-05 22.1 0.0 9.8e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ ParA PF10609.4 ETO07795.1 - 0.0021 17.8 0.5 0.025 14.4 0.2 2.4 2 1 0 2 2 2 1 ParA/MinD ATPase like AAA_31 PF13614.1 ETO07795.1 - 0.0032 17.4 0.1 0.073 13.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain YhjQ PF06564.7 ETO07795.1 - 0.016 14.5 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 YhjQ protein COG5 PF10392.4 ETO07795.1 - 0.048 13.6 0.0 0.092 12.7 0.0 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 WD40 PF00400.27 ETO07797.1 - 1.2e-10 40.8 4.5 1.8e-07 30.7 1.4 3.3 3 1 1 4 4 4 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO07797.1 - 0.0092 14.7 0.2 0.01 14.6 0.1 1.3 1 1 0 1 1 1 1 Nup133 N terminal like HAD PF12710.2 ETO07797.1 - 0.017 15.2 0.1 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DNA_pol3_alpha PF07733.7 ETO07797.1 - 0.031 12.7 0.1 0.032 12.6 0.1 1.1 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha subunit PH PF00169.24 ETO07800.1 - 0.00026 21.1 0.3 0.00026 21.1 0.2 4.9 4 1 0 4 4 4 2 PH domain Ras PF00071.17 ETO07801.1 - 7.5e-42 142.4 2.9 6.6e-41 139.4 0.2 2.6 2 1 0 2 2 2 1 Ras family PAE PF03283.8 ETO07801.1 - 2.4e-21 75.7 2.0 4.8e-21 74.8 1.4 1.5 1 0 0 1 1 1 1 Pectinacetylesterase Miro PF08477.8 ETO07801.1 - 6e-17 62.2 1.2 1.2e-15 58.0 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO07801.1 - 2.6e-11 43.0 3.3 2.6e-10 39.8 0.1 3.0 2 1 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO07801.1 - 0.00013 21.4 0.0 0.00031 20.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 ETO07801.1 - 0.00067 19.6 0.2 0.002 18.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF809 PF05663.6 ETO07801.1 - 0.035 14.0 0.1 0.12 12.3 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF809) WD40 PF00400.27 ETO07802.1 - 9.8e-11 41.1 1.8 3.4e-10 39.4 0.2 2.2 2 1 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO07802.1 - 0.0091 14.1 0.0 0.011 13.9 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO07802.1 - 0.0097 14.6 0.1 0.0097 14.6 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like zf-C3HC4_2 PF13923.1 ETO07803.1 - 0.33 11.0 5.8 0.76 9.8 2.1 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO07803.1 - 3.4 7.4 6.8 7.5 6.3 0.2 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SprA-related PF12118.3 ETO07804.1 - 0.28 10.4 21.7 0.36 10.1 15.0 1.3 1 0 0 1 1 1 0 SprA-related family DUF2547 PF10818.3 ETO07804.1 - 1.4 9.6 12.8 26 5.5 7.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) Corona_nucleoca PF00937.13 ETO07804.1 - 3.8 6.3 23.3 0.0083 15.1 5.7 2.0 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein WD40 PF00400.27 ETO07805.1 - 8.7e-64 209.3 24.4 1.2e-11 44.0 0.0 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO07805.1 - 1.4e-10 39.9 1.8 0.0048 15.0 0.1 5.3 1 1 5 6 6 6 3 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO07805.1 - 0.00022 21.5 0.8 0.00081 19.7 0.2 2.3 1 1 1 2 2 2 1 TRAF-type zinc finger Uso1_p115_C PF04871.8 ETO07805.1 - 1 9.3 34.0 0.02 14.8 9.4 2.5 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region GED PF02212.13 ETO07806.1 - 0.09 12.6 2.4 0.21 11.4 1.6 1.6 1 0 0 1 1 1 0 Dynamin GTPase effector domain XLF PF09302.6 ETO07808.1 - 0.0052 16.5 0.3 0.0092 15.7 0.2 1.4 1 0 0 1 1 1 1 XLF (XRCC4-like factor) RGS PF00615.14 ETO07808.1 - 0.021 14.9 1.5 5.1 7.2 0.1 2.4 2 0 0 2 2 2 0 Regulator of G protein signaling domain Tctex-1 PF03645.8 ETO07808.1 - 0.16 11.8 1.4 22 4.9 0.3 2.7 2 1 0 2 2 2 0 Tctex-1 family RRN3 PF05327.6 ETO07809.1 - 0.13 10.3 13.0 0.19 9.8 9.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Mem_trans PF03547.13 ETO07809.1 - 2.8 6.1 5.6 5.4 5.2 3.9 1.6 1 1 0 1 1 1 0 Membrane transport protein DUF3464 PF11947.3 ETO07809.1 - 2.9 7.3 8.4 50 3.3 5.8 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3464) Daxx PF03344.10 ETO07809.1 - 9.2 4.6 28.7 12 4.2 19.9 1.1 1 0 0 1 1 1 0 Daxx Family RhoGAP PF00620.22 ETO07810.1 - 0.032 13.8 0.1 0.045 13.3 0.1 1.2 1 0 0 1 1 1 0 RhoGAP domain Actin PF00022.14 ETO07811.1 - 1.8e-20 72.7 0.0 2.6e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Actin Pyrophosphatase PF00719.14 ETO07813.1 - 2.3e-38 131.1 0.1 2.8e-38 130.7 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase DUF3452 PF11934.3 ETO07816.1 - 6.4 6.0 9.0 1.2 8.4 3.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) HlyC PF02794.11 ETO07817.1 - 0.044 13.3 1.0 0.064 12.8 0.6 1.4 1 1 0 1 1 1 0 RTX toxin acyltransferase family DUF2146 PF10220.4 ETO07817.1 - 0.38 8.6 5.4 0.47 8.3 3.7 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Casc1 PF12366.3 ETO07817.1 - 3 7.2 10.2 3.6 7.0 7.0 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 DUF912 PF06024.7 ETO07817.1 - 4.8 7.3 5.3 7.2 6.7 3.7 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1664 PF07889.7 ETO07819.1 - 3.2 7.5 9.0 0.17 11.7 2.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) GSHPx PF00255.14 ETO07820.1 - 2.8e-35 119.9 0.0 4.7e-35 119.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione peroxidase Pex14_N PF04695.8 ETO07820.1 - 0.24 11.4 7.4 0.38 10.8 5.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mucin PF01456.12 ETO07820.1 - 9.9 5.9 12.5 15 5.3 8.7 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein WD40 PF00400.27 ETO07821.1 - 9.6e-27 91.8 0.3 1e-09 37.8 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat PD40 PF07676.7 ETO07821.1 - 0.00016 21.2 3.6 0.92 9.2 0.0 4.8 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Kelch_6 PF13964.1 ETO07821.1 - 0.0069 16.5 9.1 0.79 9.9 0.1 4.9 6 0 0 6 6 6 2 Kelch motif Kelch_4 PF13418.1 ETO07821.1 - 0.013 15.2 0.1 0.41 10.4 0.0 3.4 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO07821.1 - 0.3 10.6 4.9 3.5 7.2 0.1 3.4 3 0 0 3 3 3 0 Kelch motif Rop-like PF05082.8 ETO07822.1 - 0.0043 16.4 1.3 0.0083 15.5 0.9 1.4 1 0 0 1 1 1 1 Rop-like SlyX PF04102.7 ETO07822.1 - 0.028 14.7 1.5 0.085 13.2 1.0 1.8 1 0 0 1 1 1 0 SlyX Pro-NT_NN PF07421.6 ETO07822.1 - 0.032 13.7 1.1 0.061 12.8 0.8 1.4 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor Striatin PF08232.7 ETO07822.1 - 0.13 12.5 9.5 0.026 14.8 4.0 1.6 2 0 0 2 2 2 0 Striatin family TCP PF03634.8 ETO07822.1 - 5.9 7.2 10.0 3 8.2 3.4 2.1 2 0 0 2 2 2 0 TCP family transcription factor Alpha_L_fucos PF01120.12 ETO07823.1 - 0.016 14.1 0.1 0.018 13.9 0.1 1.0 1 0 0 1 1 1 0 Alpha-L-fucosidase SWIRM PF04433.12 ETO07824.1 - 1.6e-12 47.3 0.1 3.2e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain SOBP PF15279.1 ETO07824.1 - 1.9 8.7 20.2 2.6 8.3 14.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Tubulin PF00091.20 ETO07825.1 - 5.1e-55 186.6 0.0 2.1e-54 184.6 0.0 1.8 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO07825.1 - 2e-41 140.9 0.0 3.5e-41 140.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 ETO07825.1 - 0.015 14.7 0.0 0.038 13.4 0.0 1.8 2 0 0 2 2 2 0 Tubulin domain Phage_Gp15 PF06854.6 ETO07827.1 - 0.042 13.3 4.5 0.053 13.0 3.2 1.1 1 0 0 1 1 1 0 Bacteriophage Gp15 protein DUF728 PF05304.7 ETO07827.1 - 0.44 10.7 5.4 0.69 10.1 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF728) Cpn60_TCP1 PF00118.19 ETO07830.1 - 6.7e-41 140.4 0.2 7.7e-41 140.2 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family BetaGal_dom3 PF13363.1 ETO07830.1 - 0.13 11.6 0.1 0.84 9.0 0.0 2.1 1 1 1 2 2 2 0 Beta-galactosidase, domain 3 TLD PF07534.11 ETO07832.1 - 0.016 15.2 0.2 0.028 14.3 0.1 1.5 1 0 0 1 1 1 0 TLD DUF1546 PF07571.8 ETO07832.1 - 0.023 14.8 0.0 7.9 6.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) OSR1_C PF12202.3 ETO07832.1 - 0.11 12.1 0.2 0.11 12.1 0.1 2.2 2 0 0 2 2 2 0 Oxidative-stress-responsive kinase 1 C terminal MRP-L20 PF12824.2 ETO07833.1 - 0.025 14.5 0.6 0.033 14.1 0.4 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 Crp PF00325.15 ETO07834.1 - 0.24 10.9 1.2 0.39 10.2 0.9 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family Vac14_Fig4_bd PF11916.3 ETO07834.1 - 0.47 9.5 2.8 0.72 8.9 1.1 1.8 1 1 1 2 2 2 0 Vacuolar protein 14 C-terminal Fig4p binding COQ9 PF08511.6 ETO07835.1 - 0.039 13.4 0.1 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 COQ9 Transposase_mut PF00872.13 ETO07835.1 - 0.098 11.1 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Transposase, Mutator family Ribosomal_S27 PF01599.14 ETO07835.1 - 0.33 10.8 1.9 0.62 9.9 0.2 2.3 2 0 0 2 2 2 0 Ribosomal protein S27a DUF3902 PF13042.1 ETO07836.1 - 0.11 11.7 4.2 2 7.6 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3902) Ank_2 PF12796.2 ETO07837.1 - 2.3e-10 40.6 0.2 0.005 17.1 0.0 3.9 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO07837.1 - 7.6e-06 26.2 0.7 0.038 14.5 0.0 4.9 4 2 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO07837.1 - 8.6e-05 22.4 0.2 30 5.2 0.0 5.7 6 0 0 6 6 6 1 Ankyrin repeat Ank PF00023.25 ETO07837.1 - 0.003 17.3 0.1 4.3 7.3 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeat NuA4 PF09340.5 ETO07838.1 - 0.024 14.2 0.3 0.024 14.2 0.2 2.7 3 1 0 3 3 3 0 Histone acetyltransferase subunit NuA4 VBS PF08913.5 ETO07838.1 - 0.039 14.1 1.3 0.13 12.4 0.8 2.0 2 1 0 2 2 2 0 Vinculin Binding Site tRNA_NucTran2_2 PF13735.1 ETO07839.1 - 1.7 8.4 7.8 0.13 12.1 1.6 1.9 2 0 0 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative DUF1042 PF06294.6 ETO07841.1 - 2e-33 115.2 2.2 2e-33 115.2 1.5 2.3 1 1 1 2 2 2 1 Domain of Unknown Function (DUF1042) CAMSAP_CH PF11971.3 ETO07841.1 - 1.5e-22 79.0 0.1 3.3e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.26 ETO07841.1 - 3.4e-05 23.8 0.2 3.4e-05 23.8 0.1 2.2 2 0 0 2 2 2 1 Calponin homology (CH) domain Spore_YhcN_YlaJ PF09580.5 ETO07841.1 - 0.041 14.0 12.3 0.054 13.6 8.5 1.2 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Zip PF02535.17 ETO07841.1 - 0.12 11.3 2.2 0.2 10.6 1.5 1.3 1 1 0 1 1 1 0 ZIP Zinc transporter DUF506 PF04720.7 ETO07841.1 - 0.5 9.9 6.8 0.91 9.1 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Apc15p PF05841.6 ETO07841.1 - 2.1 9.0 14.4 4.1 8.1 10.0 1.5 1 1 0 1 1 1 0 Apc15p protein Secretin_N_2 PF07655.8 ETO07841.1 - 2.8 8.3 14.5 5.8 7.3 10.1 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain Fib_alpha PF08702.5 ETO07841.1 - 3.4 7.7 15.7 6 6.9 10.2 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF912 PF06024.7 ETO07841.1 - 4 7.5 12.6 10 6.2 8.7 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Peptidase_C1 PF00112.18 ETO07842.1 - 4.1e-65 219.7 14.5 3.2e-62 210.2 10.0 2.3 1 1 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 ETO07842.1 - 1.8e-14 53.7 0.3 3.9e-14 52.6 0.2 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 ETO07842.1 - 2.5e-06 26.3 1.4 0.003 16.1 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family WD40 PF00400.27 ETO07843.1 - 9e-35 117.3 16.5 2.3e-14 52.6 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO07843.1 - 1.3e-07 30.1 1.9 0.00054 18.2 0.3 2.4 1 1 0 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO07843.1 - 0.0021 17.8 1.7 0.038 13.7 0.1 2.0 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A CDC45 PF02724.9 ETO07845.1 - 0.0016 16.6 7.4 0.0023 16.0 5.1 1.2 1 0 0 1 1 1 1 CDC45-like protein DUF1510 PF07423.6 ETO07845.1 - 0.0073 15.6 15.3 0.0073 15.6 10.6 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) Daxx PF03344.10 ETO07845.1 - 0.024 13.1 10.6 0.033 12.6 7.4 1.1 1 0 0 1 1 1 0 Daxx Family Mem_trans PF03547.13 ETO07845.1 - 0.049 11.9 2.5 0.067 11.4 1.8 1.2 1 0 0 1 1 1 0 Membrane transport protein Nop14 PF04147.7 ETO07845.1 - 0.072 11.0 13.7 0.13 10.2 9.5 1.3 1 0 0 1 1 1 0 Nop14-like family Menin PF05053.8 ETO07845.1 - 0.2 9.7 9.2 0.28 9.2 6.4 1.1 1 0 0 1 1 1 0 Menin CENP-T PF15511.1 ETO07845.1 - 1.8 7.7 14.6 5 6.2 6.5 2.0 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T NOA36 PF06524.7 ETO07845.1 - 6.7 5.8 12.9 9.7 5.3 8.9 1.3 1 0 0 1 1 1 0 NOA36 protein 7tm_2 PF00002.19 ETO07846.1 - 9.1e-06 24.9 8.1 1.1e-05 24.6 5.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF3301 PF11743.3 ETO07846.1 - 0.015 14.8 0.0 1.5 8.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) FA_desaturase PF00487.19 ETO07846.1 - 3.2 7.1 6.6 9.9 5.5 4.6 1.7 1 1 0 1 1 1 0 Fatty acid desaturase DUF3543 PF12063.3 ETO07848.1 - 0.022 13.9 1.1 0.029 13.5 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3543) Pneumovirus_M2 PF06436.6 ETO07848.1 - 0.04 13.1 1.1 0.063 12.5 0.7 1.4 1 1 0 1 1 1 0 Pneumovirus matrix protein 2 (M2) B-block_TFIIIC PF04182.7 ETO07849.1 - 3.6e-10 39.5 0.2 6e-05 22.8 0.0 2.7 2 0 0 2 2 2 2 B-block binding subunit of TFIIIC z-alpha PF02295.12 ETO07849.1 - 0.03 14.0 1.5 2.4 7.9 0.1 3.5 3 0 0 3 3 3 0 Adenosine deaminase z-alpha domain DUF3791 PF12668.2 ETO07849.1 - 0.036 13.6 0.3 0.2 11.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) WND PF07861.6 ETO07849.1 - 0.065 12.2 0.2 0.099 11.6 0.2 1.2 1 0 0 1 1 1 0 WisP family N-Terminal Region PHTB1_C PF14728.1 ETO07851.1 - 0.0065 15.3 0.2 0.008 15.0 0.2 1.1 1 0 0 1 1 1 1 PTHB1 C-terminus 7TMR-HDED PF07697.6 ETO07851.1 - 0.072 12.8 0.6 0.1 12.3 0.4 1.3 1 0 0 1 1 1 0 7TM-HD extracellular UPF0370 PF13980.1 ETO07854.1 - 0.29 10.9 0.2 0.29 10.9 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) Nop52 PF05997.7 ETO07856.1 - 5.1e-31 107.7 6.6 2.7e-29 102.1 4.6 2.8 1 1 0 1 1 1 1 Nucleolar protein,Nop52 DUF1904 PF08921.6 ETO07856.1 - 0.059 13.4 0.1 6.1 6.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1904) FAT PF02259.18 ETO07856.1 - 0.067 12.1 2.9 1.9 7.4 0.1 2.1 1 1 0 2 2 2 0 FAT domain DUF4441 PF14536.1 ETO07857.1 - 0.13 12.2 10.1 0.19 11.6 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) DUF3421 PF11901.3 ETO07858.1 - 0.0025 17.5 0.7 0.12 12.1 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3421) DUF2371 PF10177.4 ETO07858.1 - 0.0025 17.6 0.0 0.0048 16.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2371) Peptidase_C14 PF00656.17 ETO07859.1 - 1.6e-10 41.1 1.3 2.3e-10 40.5 0.9 1.2 1 0 0 1 1 1 1 Caspase domain Lumazine_bd_2 PF12893.2 ETO07859.1 - 0.0099 16.4 0.0 0.022 15.3 0.0 1.6 1 0 0 1 1 1 1 Putative lumazine-binding Dynein_heavy PF03028.10 ETO07860.1 - 6e-81 272.5 0.0 9.5e-80 268.5 0.0 3.7 3 1 1 4 4 4 2 Dynein heavy chain and region D6 of dynein motor MT PF12777.2 ETO07860.1 - 1.5e-41 142.2 10.5 3.2e-41 141.2 7.3 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 ETO07860.1 - 1.8e-23 82.5 0.1 6.6e-14 51.3 0.0 2.7 1 1 1 2 2 2 2 ATP-binding dynein motor region D5 Reo_sigmaC PF04582.7 ETO07860.1 - 0.0013 18.0 0.4 0.0013 18.0 0.3 2.3 2 0 0 2 2 2 1 Reovirus sigma C capsid protein BRE1 PF08647.6 ETO07860.1 - 0.0045 16.9 11.6 0.0045 16.9 8.0 4.1 3 1 0 3 3 3 1 BRE1 E3 ubiquitin ligase Sec8_exocyst PF04048.9 ETO07860.1 - 0.0084 15.7 2.5 0.0084 15.7 1.7 3.3 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain DUF342 PF03961.8 ETO07860.1 - 0.62 8.4 27.0 0.028 12.8 2.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF342) Tropomyosin PF00261.15 ETO07860.1 - 0.93 8.5 43.8 0.15 11.1 7.5 3.4 3 0 0 3 3 3 0 Tropomyosin Spc7 PF08317.6 ETO07860.1 - 1.1 7.9 35.0 2 6.9 4.4 3.4 3 0 0 3 3 3 0 Spc7 kinetochore protein Fib_alpha PF08702.5 ETO07860.1 - 3.7 7.6 24.7 1.1 9.3 2.3 3.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF912 PF06024.7 ETO07862.1 - 0.00079 19.4 1.3 0.0011 18.9 0.9 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) 7tm_1 PF00001.16 ETO07862.1 - 0.035 13.2 0.6 0.039 13.0 0.4 1.2 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Viral_Beta_CD PF04530.7 ETO07862.1 - 0.12 12.5 1.3 0.15 12.1 0.9 1.1 1 0 0 1 1 1 0 Viral Beta C/D like family Tubulin PF00091.20 ETO07863.1 - 9.8e-59 198.7 0.2 1.5e-58 198.2 0.2 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO07863.1 - 6.8e-35 119.8 0.2 1.4e-34 118.8 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain ATP-synt_ab_N PF02874.18 ETO07867.1 - 3e-05 24.1 0.0 5.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain G-alpha PF00503.15 ETO07868.1 - 2.4e-26 92.3 3.6 1.3e-18 66.9 0.3 3.0 2 1 0 2 2 2 2 G-protein alpha subunit DUF3796 PF12676.2 ETO07868.1 - 0.058 13.6 3.6 0.078 13.1 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) DUF962 PF06127.6 ETO07868.1 - 0.74 9.7 3.8 2.3 8.1 2.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF962) SDA1 PF05285.7 ETO07869.1 - 0.026 13.8 18.7 0.031 13.5 13.0 1.1 1 0 0 1 1 1 0 SDA1 TP53IP5 PF15331.1 ETO07869.1 - 0.17 11.7 9.7 0.2 11.5 6.7 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Ribosomal_L6e PF01159.14 ETO07869.1 - 0.58 10.4 0.1 0.58 10.4 0.0 2.2 1 1 1 2 2 2 0 Ribosomal protein L6e Tyrosinase PF00264.15 ETO07869.1 - 1.2 9.2 12.4 1.4 8.9 8.6 1.1 1 0 0 1 1 1 0 Common central domain of tyrosinase His_Phos_1 PF00300.17 ETO07870.1 - 2.6e-07 30.8 0.0 8.5e-07 29.1 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF3562 PF12085.3 ETO07872.1 - 0.034 13.9 0.2 0.066 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3562) Apolipoprotein PF01442.13 ETO07872.1 - 0.069 12.6 11.2 0.11 12.0 7.8 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain eIF-3c_N PF05470.7 ETO07872.1 - 0.14 10.1 12.5 0.17 9.9 8.7 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Baculo_PEP_C PF04513.7 ETO07872.1 - 0.28 10.9 7.3 0.83 9.4 5.0 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3482 PF11981.3 ETO07872.1 - 0.44 9.7 6.9 0.39 9.9 3.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3482) MitMem_reg PF13012.1 ETO07872.1 - 0.6 10.2 11.6 0.43 10.6 2.9 2.3 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function ICL PF00463.16 ETO07872.1 - 1.1 7.3 6.2 0.12 10.5 0.9 1.7 1 1 1 2 2 2 0 Isocitrate lyase family Nipped-B_C PF12830.2 ETO07872.1 - 1.5 8.4 7.0 0.63 9.6 3.3 1.5 1 1 0 1 1 1 0 Sister chromatid cohesion C-terminus DUF4407 PF14362.1 ETO07872.1 - 1.5 7.7 15.0 2.2 7.1 10.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3492 PF11997.3 ETO07872.1 - 2.3 7.7 5.2 2.9 7.3 3.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3492) DUF883 PF05957.8 ETO07872.1 - 2.9 8.3 6.7 2 8.8 3.3 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF1788 PF08747.6 ETO07872.1 - 3 7.7 8.1 0.85 9.4 2.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1788) Seryl_tRNA_N PF02403.17 ETO07872.1 - 3.6 7.6 18.9 6.7 6.7 7.2 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TBCA PF02970.11 ETO07872.1 - 4.2 7.5 17.3 0.78 9.8 9.0 1.9 1 1 0 1 1 1 0 Tubulin binding cofactor A DDE_Tnp_IS66 PF03050.9 ETO07872.1 - 5.7 6.0 8.6 4 6.5 5.2 1.3 1 1 0 1 1 1 0 Transposase IS66 family P4Ha_N PF08336.6 ETO07872.1 - 6.2 6.6 15.4 1.2 8.9 6.5 2.3 1 1 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF4175 PF13779.1 ETO07872.1 - 6.8 4.2 12.6 8.9 3.8 8.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4175) CRF PF00473.12 ETO07872.1 - 8.3 6.5 6.7 8.8 6.5 0.1 2.4 2 0 0 2 2 2 0 Corticotropin-releasing factor family XRN_N PF03159.13 ETO07873.1 - 9.4e-73 244.4 0.2 9.4e-73 244.4 0.1 2.2 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus CobT PF06213.7 ETO07873.1 - 0.0088 15.2 15.5 0.015 14.4 10.7 1.3 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 ETO07873.1 - 0.048 11.6 19.1 0.064 11.1 13.2 1.2 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 ETO07873.1 - 1.3 8.2 20.1 2.2 7.5 13.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Daxx PF03344.10 ETO07873.1 - 3.5 5.9 20.5 5.4 5.3 14.2 1.2 1 0 0 1 1 1 0 Daxx Family WD40 PF00400.27 ETO07875.1 - 3.4e-56 185.2 28.9 1.3e-11 43.8 0.8 7.8 7 1 0 7 7 7 6 WD domain, G-beta repeat zf-TRAF PF02176.13 ETO07875.1 - 2e-06 28.0 3.4 2e-06 28.0 2.3 3.0 3 0 0 3 3 3 1 TRAF-type zinc finger IncA PF04156.9 ETO07875.1 - 0.11 12.1 5.2 0.19 11.3 3.6 1.4 1 0 0 1 1 1 0 IncA protein Laminin_II PF06009.7 ETO07875.1 - 0.37 10.5 5.1 0.76 9.5 3.5 1.5 1 0 0 1 1 1 0 Laminin Domain II bZIP_1 PF00170.16 ETO07875.1 - 9 6.3 7.1 23 5.0 0.9 2.6 1 1 1 2 2 2 0 bZIP transcription factor Nop25 PF09805.4 ETO07876.1 - 0.0095 16.0 14.0 0.0095 16.0 9.7 3.8 3 1 0 3 3 3 1 Nucleolar protein 12 (25kDa) Pkinase PF00069.20 ETO07877.1 - 2.2e-44 151.5 0.2 5e-44 150.3 0.1 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO07877.1 - 7.8e-22 77.5 0.1 3e-12 46.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 ETO07877.1 - 8.7e-05 21.6 0.0 0.13 11.1 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 ETO07877.1 - 0.00033 19.7 0.0 0.0005 19.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family NUC129 PF08157.6 ETO07877.1 - 0.12 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 NUC129 domain WD40 PF00400.27 ETO07881.1 - 3.9e-52 172.3 21.5 1.1e-11 44.1 0.0 6.7 6 1 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO07881.1 - 2.5e-09 35.8 8.3 0.00057 18.1 0.3 4.9 2 2 2 5 5 5 5 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO07881.1 - 0.015 14.6 2.6 0.039 13.2 1.0 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4221) VEFS-Box PF09733.4 ETO07881.1 - 0.1 12.2 0.3 2.1 7.9 0.2 2.4 2 0 0 2 2 2 0 VEFS-Box of polycomb protein WD40 PF00400.27 ETO07882.1 - 2.8e-21 74.5 10.4 1e-09 37.9 0.2 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO07882.1 - 0.0036 15.5 0.0 0.0068 14.6 0.0 1.5 1 1 0 1 1 1 1 Nucleoporin Nup120/160 DUF3417 PF11897.3 ETO07883.1 - 0.091 12.7 0.7 0.35 10.8 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3417) Rho_Binding PF08912.6 ETO07884.1 - 0.0014 18.8 10.1 0.018 15.3 2.8 2.1 2 0 0 2 2 2 2 Rho Binding Sigma70_ner PF04546.8 ETO07884.1 - 0.0025 17.4 4.4 0.0026 17.3 3.0 1.0 1 0 0 1 1 1 1 Sigma-70, non-essential region DUF1759 PF03564.10 ETO07884.1 - 0.0063 16.3 2.2 0.0077 16.0 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) DUF2608 PF11019.3 ETO07884.1 - 0.012 14.5 2.2 0.017 14.0 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) Glyco_hydr_30_2 PF14587.1 ETO07884.1 - 0.017 14.0 0.2 0.019 13.9 0.1 1.0 1 0 0 1 1 1 0 O-Glycosyl hydrolase family 30 TetR PF13972.1 ETO07884.1 - 0.027 13.9 1.0 0.031 13.7 0.7 1.3 1 0 0 1 1 1 0 Bacterial transcriptional repressor AAA_27 PF13514.1 ETO07884.1 - 0.049 11.3 3.5 0.051 11.2 2.4 1.0 1 0 0 1 1 1 0 AAA domain DUF501 PF04417.7 ETO07884.1 - 0.054 13.3 1.7 0.088 12.6 1.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF501) RNA_pol_Rpb1_6 PF04992.9 ETO07884.1 - 0.091 12.4 2.4 0.09 12.5 1.7 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 TrbM PF07424.6 ETO07884.1 - 0.11 12.4 1.2 0.12 12.3 0.8 1.1 1 0 0 1 1 1 0 TrbM zf-C4pol PF14260.1 ETO07884.1 - 0.32 11.0 2.5 0.25 11.3 0.7 1.5 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta DUF1690 PF07956.6 ETO07884.1 - 0.33 10.9 9.3 0.7 9.8 3.2 2.0 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) XhlA PF10779.4 ETO07884.1 - 0.39 10.6 6.4 0.16 11.8 1.5 1.9 2 0 0 2 2 2 0 Haemolysin XhlA Phage_GP20 PF06810.6 ETO07884.1 - 0.39 10.1 8.8 0.45 9.9 6.1 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF1366 PF07104.6 ETO07884.1 - 0.57 9.8 4.6 0.16 11.5 1.4 1.3 2 0 0 2 2 1 0 Protein of unknown function (DUF1366) AAA_23 PF13476.1 ETO07884.1 - 0.67 10.2 8.2 0.75 10.0 5.7 1.1 1 0 0 1 1 1 0 AAA domain Tropomyosin_1 PF12718.2 ETO07884.1 - 0.91 9.3 11.7 1 9.2 8.1 1.0 1 0 0 1 1 1 0 Tropomyosin like DUF4404 PF14357.1 ETO07884.1 - 1.1 9.6 4.6 1.9 8.9 3.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) APG6 PF04111.7 ETO07884.1 - 1.9 7.4 9.4 2.1 7.3 6.5 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2458 PF10454.4 ETO07884.1 - 2 8.2 7.5 3.1 7.6 5.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2458) Med4 PF10018.4 ETO07884.1 - 2.3 7.5 7.6 12 5.2 5.2 1.8 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Seryl_tRNA_N PF02403.17 ETO07884.1 - 2.8 7.9 9.0 3.7 7.6 2.5 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain AKNA PF12443.3 ETO07884.1 - 3.9 7.5 7.9 11 6.1 5.5 1.6 1 1 0 1 1 1 0 AT-hook-containing transcription factor IncA PF04156.9 ETO07884.1 - 4.7 6.7 10.4 5.9 6.4 7.2 1.2 1 0 0 1 1 1 0 IncA protein Bud13 PF09736.4 ETO07884.1 - 6.1 7.0 7.5 7 6.8 5.2 1.0 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF2630 PF10944.3 ETO07884.1 - 6.4 6.9 7.7 6.9 6.8 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2630) VacJ PF04333.8 ETO07885.1 - 0.049 13.0 0.0 0.17 11.3 0.0 1.9 1 0 0 1 1 1 0 VacJ like lipoprotein NusB PF01029.13 ETO07885.1 - 2.5 8.1 10.9 0.23 11.4 0.1 3.4 3 1 0 3 3 3 0 NusB family Pkinase PF00069.20 ETO07886.1 - 1.3e-08 34.2 8.6 4.1e-05 22.8 0.0 3.1 3 1 0 3 3 3 2 Protein kinase domain Macoilin PF09726.4 ETO07886.1 - 1.8 6.7 33.2 2.1 6.5 23.0 1.1 1 0 0 1 1 1 0 Transmembrane protein HTH_Tnp_Tc3_2 PF01498.13 ETO07887.1 - 3.1e-11 43.1 11.3 5e-10 39.3 4.9 2.4 2 0 0 2 2 2 2 Transposase HTH_38 PF13936.1 ETO07887.1 - 6.3e-05 22.4 0.0 0.00016 21.1 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain DDE_3 PF13358.1 ETO07887.1 - 0.0059 16.3 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_1 PF11427.3 ETO07887.1 - 0.093 12.3 0.7 0.31 10.6 0.1 2.1 2 0 0 2 2 2 0 Tc3 transposase TPR_12 PF13424.1 ETO07888.1 - 1.6e-102 335.5 31.0 5.4e-19 67.9 1.4 9.4 5 3 4 10 10 10 10 Tetratricopeptide repeat TPR_11 PF13414.1 ETO07888.1 - 1.3e-59 197.7 42.6 1.8e-09 37.1 2.0 9.7 7 2 2 9 9 9 9 TPR repeat TPR_2 PF07719.12 ETO07888.1 - 5.6e-48 157.0 61.3 4.8e-05 22.9 0.0 14.7 15 0 0 15 15 15 12 Tetratricopeptide repeat TPR_1 PF00515.23 ETO07888.1 - 2.1e-45 150.5 78.2 0.00024 20.5 0.3 16.3 16 0 0 16 16 16 12 Tetratricopeptide repeat TPR_8 PF13181.1 ETO07888.1 - 3.8e-40 132.6 92.5 0.0016 18.1 0.4 15.9 16 0 0 16 16 16 13 Tetratricopeptide repeat TPR_7 PF13176.1 ETO07888.1 - 4.9e-37 122.7 27.6 0.002 17.7 0.5 13.8 14 0 0 14 14 14 9 Tetratricopeptide repeat TPR_10 PF13374.1 ETO07888.1 - 1.9e-35 119.7 0.0 0.00038 20.2 0.0 13.2 14 0 0 14 14 13 5 Tetratricopeptide repeat TPR_16 PF13432.1 ETO07888.1 - 8.8e-19 67.6 0.3 0.083 13.5 0.0 8.1 7 2 1 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 ETO07888.1 - 7.1e-15 54.1 0.0 6 7.7 0.0 11.3 10 3 3 13 13 11 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO07888.1 - 5.4e-13 48.0 17.9 0.054 13.7 0.1 12.7 14 0 0 14 14 14 3 Tetratricopeptide repeat Apc3 PF12895.2 ETO07888.1 - 8.8e-13 48.2 36.8 0.03 14.4 1.9 7.9 2 1 5 7 7 7 6 Anaphase-promoting complex, cyclosome, subunit 3 Peptidase_C14 PF00656.17 ETO07888.1 - 3.5e-11 43.2 1.3 8.3e-11 42.0 0.9 1.7 1 0 0 1 1 1 1 Caspase domain TPR_6 PF13174.1 ETO07888.1 - 1.7e-08 34.3 17.3 3.1 8.4 0.1 12.2 14 0 0 14 14 13 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO07888.1 - 2.9e-07 30.7 10.7 0.17 12.2 0.3 7.6 5 3 2 7 7 7 1 Tetratricopeptide repeat DUF357 PF04010.8 ETO07888.1 - 0.0062 16.2 18.2 0.056 13.1 0.1 6.4 4 1 3 7 7 7 2 Protein of unknown function (DUF357) Fis1_TPR_C PF14853.1 ETO07888.1 - 0.017 14.9 14.8 0.72 9.7 0.1 5.9 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.2 ETO07888.1 - 0.07 12.9 8.1 0.48 10.2 0.0 4.3 5 0 0 5 5 4 0 Domain of Unknown Function (DUF3856) TPR_3 PF07720.7 ETO07888.1 - 3.1 7.6 30.7 13 5.6 1.2 9.4 9 1 0 9 9 9 0 Tetratricopeptide repeat TPR_21 PF09976.4 ETO07888.1 - 8.5 6.3 13.2 16 5.4 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF3605 PF12239.3 ETO07889.1 - 0.021 14.6 2.2 0.067 13.0 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3605) MCPsignal PF00015.16 ETO07889.1 - 0.022 14.3 2.9 0.21 11.0 0.2 2.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain BLOC1_2 PF10046.4 ETO07889.1 - 0.041 14.0 11.9 0.069 13.2 1.1 3.4 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.6 ETO07889.1 - 0.071 12.9 5.9 0.53 10.1 0.5 3.4 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) TMF_TATA_bd PF12325.3 ETO07889.1 - 0.09 12.5 3.5 0.072 12.8 1.3 1.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding NPV_P10 PF05531.7 ETO07889.1 - 0.17 12.1 4.8 1 9.6 0.2 3.3 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Occludin_ELL PF07303.8 ETO07889.1 - 0.24 12.1 5.7 0.63 10.8 0.6 2.6 1 1 1 2 2 2 0 Occludin homology domain Laminin_II PF06009.7 ETO07889.1 - 0.24 11.1 6.9 0.79 9.4 2.4 2.5 1 1 2 3 3 3 0 Laminin Domain II ABC1 PF03109.11 ETO07889.1 - 0.24 11.3 3.1 0.94 9.4 0.5 2.3 1 1 1 2 2 2 0 ABC1 family AKNA PF12443.3 ETO07889.1 - 0.3 11.1 2.4 0.76 9.8 0.1 2.4 1 1 0 2 2 2 0 AT-hook-containing transcription factor ALO PF04030.9 ETO07889.1 - 0.74 9.3 7.7 4.7 6.7 1.3 2.2 1 1 1 2 2 2 0 D-arabinono-1,4-lactone oxidase UPF0118 PF01594.11 ETO07889.1 - 0.98 8.3 2.5 7 5.5 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF20 DUF349 PF03993.7 ETO07889.1 - 2.3 8.4 7.0 0.57 10.3 0.3 2.8 2 1 1 3 3 3 0 Domain of Unknown Function (DUF349) MUG113 PF13455.1 ETO07890.1 - 0.043 14.2 0.2 0.069 13.6 0.2 1.5 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 Kelch_2 PF07646.10 ETO07891.1 - 0.00039 20.0 1.2 1.1 9.1 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO07891.1 - 0.00063 19.8 0.4 0.39 10.9 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 ETO07891.1 - 0.0047 16.8 0.0 5.7 6.9 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 ETO07891.1 - 0.0078 15.7 0.6 1.5 8.4 0.0 3.4 3 0 0 3 3 3 1 Kelch motif DUF1793 PF08760.6 ETO07891.1 - 0.024 14.4 0.0 0.38 10.6 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1793) DUF2120 PF09893.4 ETO07891.1 - 0.06 13.2 0.0 0.2 11.6 0.0 1.9 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) Kelch_4 PF13418.1 ETO07892.1 - 1.4e-06 27.9 0.6 0.00072 19.2 0.0 3.7 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO07892.1 - 0.00055 20.0 5.8 1.8 8.8 0.1 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO07892.1 - 0.017 14.9 4.6 7.9 6.4 0.1 4.9 5 0 0 5 5 5 0 Kelch motif TGT_C2 PF14810.1 ETO07894.1 - 0.18 11.6 0.5 0.31 10.8 0.3 1.4 1 0 0 1 1 1 0 Patch-forming domain C2 of tRNA-guanine transglycosylase DUF2951 PF11166.3 ETO07894.1 - 3.1 7.7 16.5 2 8.3 10.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2951) Actin PF00022.14 ETO07896.1 - 0.00019 19.9 0.0 0.00025 19.5 0.0 1.3 1 0 0 1 1 1 1 Actin GTP_EFTU PF00009.22 ETO07896.1 - 0.0031 16.9 0.3 0.0051 16.2 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SET PF00856.23 ETO07897.1 - 0.0032 17.8 0.0 0.007 16.6 0.0 1.5 1 0 0 1 1 1 1 SET domain HSP90 PF00183.13 ETO07898.1 - 6.9e-77 259.0 23.9 5.2e-38 130.7 4.2 4.4 2 1 2 4 4 4 4 Hsp90 protein Rep_fac_C PF08542.6 ETO07898.1 - 0.02 14.8 0.1 0.078 12.9 0.1 2.0 1 0 0 1 1 1 0 Replication factor C C-terminal domain LOH1CR12 PF10158.4 ETO07898.1 - 0.069 12.9 2.0 0.11 12.3 0.2 2.3 2 0 0 2 2 2 0 Tumour suppressor protein MFS_1 PF07690.11 ETO07899.1 - 3.6e-06 25.9 0.8 1.6e-05 23.7 0.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETO07899.1 - 0.068 11.7 2.0 0.1 11.1 1.3 1.3 1 1 0 1 1 1 0 Sugar (and other) transporter MFS_1 PF07690.11 ETO07900.1 - 3e-25 88.6 2.5 3.9e-25 88.3 1.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETO07900.1 - 5.6e-05 21.8 14.0 0.004 15.7 10.1 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter TOM13 PF08219.6 ETO07900.1 - 0.55 10.0 2.4 1.3 8.8 0.4 2.3 2 0 0 2 2 2 0 Outer membrane protein TOM13 GSAP-16 PF14959.1 ETO07901.1 - 0.029 14.1 0.2 0.067 12.9 0.2 1.6 1 0 0 1 1 1 0 gamma-Secretase-activating protein C-term EF-hand_6 PF13405.1 ETO07902.1 - 6.5e-06 25.5 0.5 0.068 13.0 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 ETO07902.1 - 7.3e-06 24.9 1.0 0.014 14.6 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 ETO07902.1 - 2.5e-05 23.7 1.5 0.00086 18.8 0.3 2.8 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 ETO07902.1 - 0.00073 19.6 3.4 0.0091 16.1 2.3 2.5 1 1 0 1 1 1 1 EF-hand domain pair WD40 PF00400.27 ETO07903.1 - 4.2e-12 45.4 0.5 2.3e-08 33.5 0.0 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO07903.1 - 0.12 10.5 0.1 0.12 10.4 0.1 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Lig_chan-Glu_bd PF10613.4 ETO07903.1 - 0.2 11.6 0.6 1.2 9.1 0.1 2.4 2 1 1 3 3 3 0 Ligated ion channel L-glutamate- and glycine-binding site WD40 PF00400.27 ETO07904.1 - 5e-06 26.1 6.3 0.0052 16.6 0.2 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat TPR_12 PF13424.1 ETO07906.1 - 1.2e-34 118.1 5.8 1.4e-15 56.9 0.3 3.2 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO07906.1 - 2.3e-15 55.1 14.3 4.8e-06 25.9 0.4 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO07906.1 - 6.9e-14 50.5 8.7 3.6e-05 23.3 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO07906.1 - 1.1e-12 46.9 17.0 1.3e-05 24.5 0.2 4.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO07906.1 - 2.9e-12 46.0 7.0 9.9e-08 31.5 0.2 3.2 2 1 0 2 2 2 2 TPR repeat TPR_7 PF13176.1 ETO07906.1 - 1.5e-10 40.0 3.7 0.00012 21.6 0.0 4.5 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO07906.1 - 1.7e-08 34.0 0.0 0.0036 17.1 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat MIT PF04212.13 ETO07906.1 - 1.1e-05 25.1 3.0 0.0066 16.2 0.1 3.8 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_17 PF13431.1 ETO07906.1 - 1.2e-05 25.0 2.8 0.055 13.6 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO07906.1 - 0.00076 19.7 2.3 8.7 7.0 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat CRA PF06589.6 ETO07906.1 - 0.079 12.2 2.1 0.17 11.2 1.5 1.4 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) SHNi-TPR PF10516.4 ETO07906.1 - 0.085 12.1 0.0 17 4.7 0.0 2.7 2 0 0 2 2 2 0 SHNi-TPR TPR_14 PF13428.1 ETO07906.1 - 0.16 12.7 0.0 26 5.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.7 ETO07906.1 - 1.1 9.1 10.3 0.53 10.1 0.4 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.7 ETO07906.1 - 5.3 7.8 5.3 3.6 8.3 0.1 2.9 3 0 0 3 3 3 0 Sel1 repeat U-box PF04564.10 ETO07907.1 - 9.4e-09 35.1 0.1 3.7e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 U-box domain RNA_polI_A14 PF08203.6 ETO07907.1 - 0.035 14.3 0.5 0.11 12.8 0.4 1.9 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 Med26 PF08711.6 ETO07907.1 - 0.046 13.2 6.2 0.81 9.2 0.1 3.0 3 0 0 3 3 3 0 TFIIS helical bundle-like domain zf-Nse PF11789.3 ETO07907.1 - 0.058 12.9 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Trns_repr_metal PF02583.12 ETO07907.1 - 0.13 12.5 2.2 0.45 10.7 1.5 1.9 1 1 0 1 1 1 0 Metal-sensitive transcriptional repressor MIT PF04212.13 ETO07907.1 - 0.32 10.8 4.3 0.3 10.9 1.5 2.1 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain XkdW PF09636.5 ETO07907.1 - 0.37 10.6 4.9 2.2 8.1 0.2 2.7 1 1 1 2 2 2 0 XkdW protein Muted PF14942.1 ETO07907.1 - 0.82 9.5 11.4 0.46 10.3 0.4 2.3 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Swi5 PF07061.6 ETO07907.1 - 1.2 8.9 8.0 3.9 7.3 0.2 2.9 1 1 1 2 2 2 0 Swi5 Med4 PF10018.4 ETO07907.1 - 2.7 7.3 8.9 1.6 8.1 0.5 2.3 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF972 PF06156.8 ETO07907.1 - 3.9 7.8 8.9 1.7 9.0 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Kelch_6 PF13964.1 ETO07908.1 - 4.5e-05 23.4 2.4 0.52 10.5 0.0 4.1 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 ETO07908.1 - 0.022 14.8 2.9 0.77 9.9 0.1 3.6 3 1 1 4 4 4 0 Galactose oxidase, central domain WWE PF02825.15 ETO07908.1 - 0.08 12.3 0.3 2.8 7.4 0.0 2.5 2 0 0 2 2 2 0 WWE domain DUF4339 PF14237.1 ETO07909.1 - 0.066 12.8 0.1 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4339) Kelch_3 PF13415.1 ETO07910.1 - 0.019 15.1 0.2 0.059 13.5 0.1 1.9 1 0 0 1 1 1 0 Galactose oxidase, central domain SusD-like_3 PF14322.1 ETO07911.1 - 0.16 11.9 5.8 0.21 11.6 4.0 1.1 1 0 0 1 1 1 0 Starch-binding associating with outer membrane DUF4358 PF14270.1 ETO07911.1 - 0.17 11.8 2.9 0.47 10.3 1.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) FAD_binding_4 PF01565.18 ETO07913.1 - 0.00034 20.0 0.2 0.0013 18.2 0.0 2.0 2 1 0 2 2 2 1 FAD binding domain HBS1_N PF08938.5 ETO07913.1 - 0.0077 16.3 0.8 0.021 14.9 0.5 1.7 1 0 0 1 1 1 1 HBS1 N-terminus SurA_N_2 PF13623.1 ETO07913.1 - 0.27 11.1 2.6 2.3 8.1 0.1 2.6 1 1 1 2 2 2 0 SurA N-terminal domain APP_E2 PF12925.2 ETO07913.1 - 0.37 10.3 4.6 0.17 11.4 0.5 2.1 3 0 0 3 3 3 0 E2 domain of amyloid precursor protein adh_short PF00106.20 ETO07914.1 - 1.6e-10 41.1 0.4 1.1e-09 38.4 0.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 ETO07914.1 - 2.8e-05 23.6 0.1 3.5e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PIP49_N PF14875.1 ETO07914.1 - 0.036 13.7 0.6 0.067 12.8 0.0 1.7 2 0 0 2 2 2 0 N-term cysteine-rich ER, FAM69 TelA PF05816.6 ETO07914.1 - 0.12 10.9 0.1 0.2 10.3 0.1 1.3 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) KR PF08659.5 ETO07914.1 - 0.15 11.7 0.5 3 7.4 0.3 2.2 1 1 0 1 1 1 0 KR domain NAD_binding_4 PF07993.7 ETO07914.1 - 0.55 9.1 2.7 4 6.2 0.3 2.4 1 1 1 2 2 2 0 Male sterility protein WD40 PF00400.27 ETO07915.1 - 5.5e-58 190.9 23.3 2.6e-13 49.3 0.0 7.2 8 0 0 8 8 8 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO07915.1 - 7.4e-09 34.2 1.8 0.01 14.0 0.0 4.5 1 1 2 4 4 4 4 Nucleoporin Nup120/160 WD40 PF00400.27 ETO07916.1 - 3.1e-33 112.4 6.2 1.5e-09 37.3 0.1 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO07916.1 - 6.1e-11 41.1 1.4 1.5e-05 23.3 0.1 3.0 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO07916.1 - 0.00043 19.1 0.5 0.41 9.3 0.1 2.2 1 1 1 2 2 2 2 Nup133 N terminal like eIF2A PF08662.6 ETO07916.1 - 0.029 14.0 0.1 4.9 6.8 0.1 2.4 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A ASFV_p27 PF06556.6 ETO07917.1 - 0.079 12.8 0.7 0.14 12.0 0.1 1.6 2 0 0 2 2 2 0 IAP-like protein p27 C-terminus 2C_adapt PF08793.5 ETO07917.1 - 0.12 12.2 0.1 0.88 9.5 0.0 2.3 2 0 0 2 2 2 0 2-cysteine adaptor domain WD40 PF00400.27 ETO07918.1 - 1.5e-24 84.9 4.1 1.9e-11 43.3 0.3 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF3942 PF13078.1 ETO07918.1 - 0.47 10.5 5.7 3.5 7.7 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3942) WD40 PF00400.27 ETO07919.1 - 3.1e-15 55.3 15.7 2.7e-08 33.3 1.0 4.1 3 1 1 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO07919.1 - 0.00033 18.9 2.4 0.00093 17.4 0.8 1.9 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Helicase_C PF00271.26 ETO07920.1 - 5.2e-16 58.2 0.0 1.1e-09 37.9 0.0 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain EPL1 PF10513.4 ETO07920.1 - 0.0059 16.8 1.8 0.01 16.0 1.2 1.5 1 0 0 1 1 1 1 Enhancer of polycomb-like DAGK_cat PF00781.19 ETO07921.1 - 1.1e-10 41.0 0.0 1.3e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Menin PF05053.8 ETO07921.1 - 0.014 13.5 1.9 0.015 13.5 1.3 1.1 1 0 0 1 1 1 0 Menin DUF912 PF06024.7 ETO07921.1 - 3.9 7.5 10.7 8.4 6.5 7.4 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) POX PF07526.6 ETO07921.1 - 7 6.8 6.9 12 6.1 4.8 1.3 1 0 0 1 1 1 0 Associated with HOX RGS PF00615.14 ETO07922.1 - 0.00019 21.5 0.7 0.0026 17.8 0.5 2.5 1 1 0 1 1 1 1 Regulator of G protein signaling domain TFIIA PF03153.8 ETO07923.1 - 5 6.9 31.0 0.38 10.6 17.8 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit fn3 PF00041.16 ETO07924.1 - 8.9e-05 22.5 0.3 0.22 11.6 0.0 3.0 2 0 0 2 2 2 2 Fibronectin type III domain M157 PF11624.3 ETO07926.1 - 0.0033 16.5 0.7 0.0039 16.3 0.5 1.1 1 0 0 1 1 1 1 MHC class I-like protein M157 N6_N4_Mtase PF01555.13 ETO07927.1 - 0.02 14.3 2.7 0.027 13.9 1.9 1.3 1 0 0 1 1 1 0 DNA methylase DUF940 PF06082.6 ETO07927.1 - 0.029 12.9 0.6 0.037 12.6 0.4 1.1 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) Folate_carrier PF01770.13 ETO07927.1 - 0.18 10.3 1.7 0.24 9.8 1.2 1.2 1 0 0 1 1 1 0 Reduced folate carrier ECIST_Cterm PF14784.1 ETO07927.1 - 0.22 11.4 4.0 0.11 12.4 1.2 1.6 2 0 0 2 2 2 0 C-terminal domain of the ECSIT protein Vma12 PF11712.3 ETO07927.1 - 0.26 10.9 1.8 0.49 10.1 1.2 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3886 PF13025.1 ETO07927.1 - 6.7 6.7 20.4 0.8 9.7 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) DcpS PF05652.7 ETO07929.1 - 0.023 15.0 0.2 0.1 13.0 0.0 2.2 2 1 0 2 2 2 0 Scavenger mRNA decapping enzyme (DcpS) N-terminal Copine PF07002.11 ETO07930.1 - 1.6e-13 50.5 0.0 2.8e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Copine WD40 PF00400.27 ETO07931.1 - 1.3e-24 85.1 3.9 4.5e-09 35.8 0.2 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO07931.1 - 1.2e-07 30.3 3.3 0.00011 20.5 0.5 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO07931.1 - 0.011 14.4 0.4 0.9 8.2 0.0 2.1 1 1 1 2 2 2 0 Nup133 N terminal like Peptidase_C14 PF00656.17 ETO07932.1 - 0.0048 16.6 0.0 0.005 16.5 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Glycos_transf_1 PF00534.15 ETO07932.1 - 0.029 13.8 0.1 0.032 13.6 0.1 1.1 1 0 0 1 1 1 0 Glycosyl transferases group 1 NACHT PF05729.7 ETO07933.1 - 3.4e-09 36.5 0.0 1.3e-08 34.6 0.0 2.1 1 1 0 1 1 1 1 NACHT domain Sec1 PF00995.18 ETO07934.1 - 3e-48 164.8 0.0 5e-48 164.1 0.0 1.2 1 1 0 1 1 1 1 Sec1 family BEX PF04538.7 ETO07934.1 - 0.31 11.2 3.9 0.14 12.3 0.6 1.8 2 0 0 2 2 2 0 Brain expressed X-linked like family Na_trans_assoc PF06512.8 ETO07935.1 - 0.0078 16.2 6.6 0.012 15.5 4.6 1.3 1 0 0 1 1 1 1 Sodium ion transport-associated DNA_pol3_a_NI PF14480.1 ETO07935.1 - 0.031 13.9 2.0 0.088 12.4 1.4 1.8 1 1 0 1 1 1 0 DNA polymerase III polC-type N-terminus I Corona_nucleoca PF00937.13 ETO07935.1 - 0.071 12.0 16.6 0.097 11.5 11.5 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein AF-4 PF05110.8 ETO07935.1 - 5.2 4.8 26.8 6.1 4.5 18.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF4614 PF15391.1 ETO07935.1 - 8.4 6.1 11.7 14 5.4 8.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) SURF2 PF05477.6 ETO07937.1 - 0.32 10.1 9.1 0.37 9.8 6.3 1.0 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) AAA_11 PF13086.1 ETO07937.1 - 2 7.9 7.3 2.2 7.8 5.1 1.0 1 0 0 1 1 1 0 AAA domain CAF-1_p150 PF11600.3 ETO07937.1 - 2.6 7.3 21.0 2.9 7.2 14.5 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CDC45 PF02724.9 ETO07937.1 - 5.6 4.8 15.6 6 4.7 10.8 1.0 1 0 0 1 1 1 0 CDC45-like protein IncA PF04156.9 ETO07937.1 - 7.2 6.1 7.8 8.1 5.9 5.4 1.2 1 0 0 1 1 1 0 IncA protein DUF724 PF05266.9 ETO07937.1 - 8.2 5.9 15.0 9.7 5.7 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ApoB100_C PF12491.3 ETO07939.1 - 0.043 13.4 0.4 0.19 11.3 0.0 2.3 2 0 0 2 2 2 0 Apolipoprotein B100 C terminal Tox-PLDMTX PF15645.1 ETO07939.1 - 5.1 7.1 12.8 2.2 8.3 4.5 2.3 1 1 1 2 2 2 0 Dermonecrotoxin of the Papain-like fold WD40 PF00400.27 ETO07940.1 - 2e-12 46.4 8.2 6.5e-09 35.3 1.2 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO07940.1 - 0.017 13.3 0.1 0.02 13.0 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 EF-hand_1 PF00036.27 ETO07941.1 - 2.4e-09 35.8 0.6 2e-05 23.5 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 ETO07941.1 - 7.4e-07 28.5 0.8 0.0012 18.5 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.1 ETO07941.1 - 9.9e-06 25.6 0.6 0.001 19.1 0.1 2.9 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 ETO07941.1 - 5e-05 22.8 0.4 0.0019 17.7 0.1 3.0 1 1 2 3 3 3 1 EF-hand domain pair EF-hand_9 PF14658.1 ETO07941.1 - 0.00052 19.8 0.0 0.0015 18.3 0.0 1.8 1 1 1 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 ETO07941.1 - 0.0023 17.1 0.0 0.22 10.9 0.0 2.6 2 0 0 2 2 2 1 EF hand Ins_P5_2-kin PF06090.7 ETO07942.1 - 0.066 12.2 0.1 0.072 12.1 0.0 1.0 1 0 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase Leu_zip PF15294.1 ETO07943.1 - 0.00092 18.4 0.8 0.00092 18.4 0.5 1.7 2 0 0 2 2 2 1 Leucine zipper Shigella_OspC PF06128.6 ETO07943.1 - 0.0012 18.4 1.8 0.0024 17.4 1.3 1.6 1 0 0 1 1 1 1 Shigella flexneri OspC protein Ank_5 PF13857.1 ETO07943.1 - 0.0027 17.9 0.0 0.041 14.1 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 ETO07943.1 - 0.0034 17.1 0.2 0.024 14.4 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 ETO07943.1 - 0.0036 17.6 0.0 0.0092 16.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) DUF2205 PF10224.4 ETO07943.1 - 0.0044 16.5 0.9 0.011 15.3 0.6 1.6 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) ATP13 PF12921.2 ETO07943.1 - 0.0084 15.4 0.2 0.021 14.1 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial ATPase expression Ank_4 PF13637.1 ETO07943.1 - 0.0091 16.4 0.2 0.018 15.5 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF3804 PF12707.2 ETO07943.1 - 0.017 14.7 0.8 2.3 7.8 0.1 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3804) ATHILA PF03078.10 ETO07946.1 - 0.052 12.1 0.1 0.057 12.0 0.1 1.0 1 0 0 1 1 1 0 ATHILA ORF-1 family Tn7_Tnp_TnsA_N PF08722.6 ETO07946.1 - 0.058 13.3 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 TnsA endonuclease N terminal DUF4286 PF14114.1 ETO07947.1 - 0.0056 16.9 0.4 0.014 15.6 0.2 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4286) DUF728 PF05304.7 ETO07947.1 - 0.39 10.8 4.0 0.12 12.5 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF728) RNaseH_C PF09293.5 ETO07947.1 - 7.4 6.5 12.7 6.1 6.7 0.6 2.4 2 1 0 2 2 2 0 T4 RNase H, C terminal BpuSI_N PF15516.1 ETO07948.1 - 0.17 11.5 1.6 0.19 11.4 1.1 1.1 1 0 0 1 1 1 0 BpuSI N-terminal domain AAA_21 PF13304.1 ETO07948.1 - 0.4 10.5 4.2 0.42 10.5 2.9 1.1 1 0 0 1 1 1 0 AAA domain ATP-synt_E PF05680.7 ETO07948.1 - 1.8 8.5 8.2 2.8 7.9 5.7 1.5 1 0 0 1 1 1 0 ATP synthase E chain ATG11 PF10377.4 ETO07948.1 - 5.8 6.8 11.1 2.4 8.0 6.2 1.5 1 1 1 2 2 2 0 Autophagy-related protein 11 Peptidase_S49_N PF08496.5 ETO07948.1 - 7.2 6.3 12.5 12 5.7 8.7 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2441 PF10386.4 ETO07949.1 - 0.031 14.3 0.1 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2441) Ins_allergen_rp PF06757.8 ETO07949.1 - 0.046 13.2 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification ComC PF03047.9 ETO07949.1 - 0.26 10.7 1.9 0.7 9.3 1.4 1.7 1 0 0 1 1 1 0 COMC family NACHT PF05729.7 ETO07950.1 - 0.036 13.7 0.0 0.039 13.6 0.0 1.3 1 1 0 1 1 1 0 NACHT domain V-ATPase_C PF03223.10 ETO07950.1 - 0.22 10.3 1.9 0.12 11.2 0.2 1.3 2 0 0 2 2 2 0 V-ATPase subunit C TT_ORF1 PF02956.9 ETO07951.1 - 0.046 12.1 5.8 0.051 12.0 4.1 1.0 1 0 0 1 1 1 0 TT viral orf 1 DUF4220 PF13968.1 ETO07951.1 - 6 5.8 6.2 7.2 5.5 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) BHD_2 PF10404.4 ETO07951.1 - 7.7 6.9 10.4 1.5 9.1 1.4 2.6 2 1 1 3 3 3 0 Rad4 beta-hairpin domain 2 Membralin PF09746.4 ETO07951.1 - 7.8 5.4 6.6 8.2 5.3 4.1 1.2 1 1 0 1 1 1 0 Tumour-associated protein DUF3210 PF11489.3 ETO07951.1 - 9.8 4.7 15.0 11 4.4 10.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3210) CITED PF04487.7 ETO07952.1 - 0.036 14.3 1.9 0.044 14.0 1.4 1.1 1 0 0 1 1 1 0 CITED POX PF07526.6 ETO07952.1 - 1.4 9.1 7.8 2.2 8.4 5.3 1.4 1 1 0 1 1 1 0 Associated with HOX Neur_chan_memb PF02932.11 ETO07952.1 - 2.5 7.9 4.7 3 7.6 3.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region WD40 PF00400.27 ETO07953.1 - 0.0016 18.2 0.0 0.0043 16.8 0.0 1.7 2 0 0 2 2 2 1 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO07953.1 - 0.11 10.8 0.1 0.13 10.5 0.1 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain Myc-LZ PF02344.10 ETO07954.1 - 8.7 6.0 8.2 10 5.8 2.4 2.6 2 0 0 2 2 2 0 Myc leucine zipper domain RVT_1 PF00078.22 ETO07955.1 - 4.1e-09 36.0 0.1 0.00027 20.3 0.0 3.0 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Kinesin PF00225.18 ETO07955.1 - 6.9e-09 34.8 0.2 6.9e-09 34.8 0.1 2.3 2 1 0 2 2 2 1 Kinesin motor domain Sec5 PF15469.1 ETO07956.1 - 0.023 14.4 0.7 0.037 13.7 0.5 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec5 Vir_act_alpha_C PF10400.4 ETO07957.1 - 5.1 7.5 7.1 4.1 7.8 0.7 2.6 1 1 2 3 3 3 0 Virulence activator alpha C-term HSP90 PF00183.13 ETO07960.1 - 9.2e-72 242.1 25.7 1.9e-68 231.1 7.1 2.7 3 0 0 3 3 3 2 Hsp90 protein PHP PF02811.14 ETO07960.1 - 0.017 14.9 2.8 0.15 11.7 1.8 2.2 1 1 0 1 1 1 0 PHP domain DUF4342 PF14242.1 ETO07960.1 - 0.071 12.8 1.5 0.27 11.0 1.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) NUDIX_2 PF13869.1 ETO07962.1 - 0.071 12.4 0.0 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 Nucleotide hydrolase PAP2_C PF14360.1 ETO07963.1 - 1.7e-15 57.0 11.7 1.7e-15 57.0 8.1 3.2 3 1 1 4 4 4 1 PAP2 superfamily C-terminal PAP2 PF01569.16 ETO07963.1 - 2.7e-06 27.0 5.1 2.7e-06 27.0 3.5 2.6 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 ETO07963.1 - 0.012 15.1 12.7 0.011 15.2 4.0 2.3 2 1 0 2 2 2 0 PAP2 superfamily TPR_11 PF13414.1 ETO07964.1 - 2.1e-16 59.3 7.5 2.4e-09 36.7 1.0 2.5 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETO07964.1 - 2.9e-09 36.1 3.5 0.0057 16.2 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO07964.1 - 8.6e-09 34.6 2.1 0.001 18.7 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO07964.1 - 1.5e-07 31.6 1.1 1.3e-06 28.6 0.2 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO07964.1 - 4.9e-07 29.8 1.7 3.3e-06 27.1 0.7 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 ETO07964.1 - 5.1e-06 26.3 0.8 0.00048 20.0 0.5 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO07964.1 - 1.9e-05 24.9 0.2 0.00032 21.0 0.1 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO07964.1 - 0.00055 20.5 0.1 0.0014 19.2 0.0 1.8 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO07964.1 - 0.0067 16.5 0.2 0.054 13.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO07964.1 - 0.03 14.1 1.3 0.59 10.0 0.1 3.1 1 1 2 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 ETO07964.1 - 0.077 13.4 5.7 1.1 9.8 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1573 PF07610.6 ETO07964.1 - 0.14 11.7 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1573) RFX5_DNA_bdg PF14621.1 ETO07965.1 - 0.017 14.7 2.6 0.017 14.7 1.8 1.5 2 0 0 2 2 2 0 RFX5 DNA-binding domain Dicty_REP PF05086.7 ETO07965.1 - 0.089 10.5 5.6 0.099 10.3 3.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3446 PF11928.3 ETO07965.1 - 0.25 11.5 12.9 0.87 9.8 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) RP-C_C PF11800.3 ETO07965.1 - 0.32 10.6 3.9 0.4 10.3 2.3 1.3 1 1 0 1 1 1 0 Replication protein C C-terminal region AT_hook PF02178.14 ETO07965.1 - 0.66 9.8 8.2 1.6 8.6 5.7 1.7 1 0 0 1 1 1 0 AT hook motif POX PF07526.6 ETO07965.1 - 0.7 10.1 5.7 0.18 12.0 1.9 1.5 2 0 0 2 2 2 0 Associated with HOX CobT PF06213.7 ETO07970.1 - 0.66 9.0 13.7 0.7 8.9 9.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Borrelia_P83 PF05262.6 ETO07970.1 - 4.1 5.5 13.6 4.7 5.3 9.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4028 PF13220.1 ETO07970.1 - 5.6 6.6 9.2 0.097 12.3 0.8 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4028) Astro_capsid PF03115.9 ETO07970.1 - 9.3 4.3 6.8 11 4.1 4.7 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor WD40 PF00400.27 ETO07971.1 - 6.1e-23 79.8 17.3 8.4e-11 41.3 0.3 4.3 4 1 0 4 4 4 3 WD domain, G-beta repeat DUF3601 PF12208.3 ETO07971.1 - 0.00084 19.2 0.6 0.96 9.4 0.0 3.0 2 1 1 3 3 3 2 Domain of unknown function (DUF3601) DUF678 PF05077.7 ETO07971.1 - 0.055 13.4 0.3 0.43 10.5 0.0 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF678) Nup160 PF11715.3 ETO07971.1 - 0.16 10.0 5.4 4.4 5.3 2.4 3.2 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO07971.1 - 0.23 10.1 6.3 10 4.7 0.2 3.0 1 1 2 3 3 3 0 Nup133 N terminal like WD40 PF00400.27 ETO07973.1 - 6.1e-149 479.2 48.8 6e-12 44.9 0.1 15.1 15 0 0 15 15 15 14 WD domain, G-beta repeat Nup160 PF11715.3 ETO07973.1 - 5.9e-18 64.3 26.0 0.068 11.2 0.3 11.5 1 1 8 11 11 11 9 Nucleoporin Nup120/160 DUF1652 PF07865.6 ETO07973.1 - 7.2e-07 28.7 2.3 17 5.1 0.0 9.4 8 2 4 12 12 12 0 Protein of unknown function (DUF1652) F420_ligase PF01996.11 ETO07973.1 - 1.2e-05 24.4 0.0 0.077 12.0 0.0 4.4 2 2 1 4 4 4 1 F420-0:Gamma-glutamyl ligase Nucleoporin_N PF08801.6 ETO07973.1 - 2.4e-05 23.2 33.3 0.18 10.5 4.3 8.6 2 1 3 6 6 6 3 Nup133 N terminal like DUF1258 PF06869.7 ETO07973.1 - 6.8e-05 22.0 5.3 2.1 7.3 0.1 5.5 3 3 3 6 6 6 1 Protein of unknown function (DUF1258) Cytochrom_D1 PF02239.11 ETO07973.1 - 0.00034 19.0 10.4 0.22 9.8 0.1 5.4 2 1 2 6 6 6 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO07973.1 - 0.00039 19.9 7.4 3.6 6.9 1.0 5.6 1 1 3 4 4 4 2 PQQ-like domain DUF3732 PF12532.3 ETO07973.1 - 0.0037 16.8 1.0 40 3.6 0.0 5.8 4 3 3 7 7 7 0 Protein of unknown function (DUF3732) Peptidase_C69 PF03577.10 ETO07973.1 - 0.0088 14.9 6.4 0.33 9.7 0.4 4.3 4 1 0 4 4 4 1 Peptidase family C69 NYD-SP28_assoc PF14775.1 ETO07973.1 - 0.017 14.8 12.0 28 4.4 0.0 9.2 13 1 1 14 14 14 0 Sperm tail C-terminal domain Imm21 PF15569.1 ETO07973.1 - 0.074 12.8 0.8 34 4.2 0.0 4.3 4 1 1 5 5 5 0 Immunity protein 21 PD40 PF07676.7 ETO07973.1 - 0.31 10.7 15.5 2.1 8.0 0.0 6.0 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO07973.1 - 0.54 10.5 3.3 73 3.7 0.0 5.3 5 2 2 7 7 6 0 Resistin PT PF04886.7 ETO07974.1 - 0.022 14.0 11.2 0.022 14.0 7.8 2.1 2 0 0 2 2 2 0 PT repeat Peptidase_C1_2 PF03051.10 ETO07976.1 - 0.0076 14.8 0.4 0.0087 14.6 0.3 1.1 1 0 0 1 1 1 1 Peptidase C1-like family DUF86 PF01934.12 ETO07976.1 - 0.062 12.9 0.4 0.12 11.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF86 LRR_6 PF13516.1 ETO07977.1 - 2.5e-05 23.8 3.5 0.82 9.9 0.3 4.2 4 0 0 4 4 4 2 Leucine Rich repeat FBPase PF00316.15 ETO07977.1 - 0.071 11.9 0.4 0.098 11.4 0.3 1.1 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase Pkinase PF00069.20 ETO07978.1 - 2.2e-44 151.5 3.5 3.9e-44 150.7 0.0 3.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO07978.1 - 6.5e-30 104.0 0.0 1.6e-26 92.9 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 ETO07978.1 - 0.0012 18.0 0.0 0.0025 16.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family AKAP7_NLS PF10469.4 ETO07980.1 - 2.1e-21 76.5 1.0 4.8e-21 75.4 0.7 1.6 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain LigT_PEase PF02834.11 ETO07980.1 - 0.073 13.0 0.1 10 6.1 0.0 2.7 2 0 0 2 2 2 0 LigT like Phosphoesterase DUF4435 PF14491.1 ETO07981.1 - 0.06 13.1 5.8 0.12 12.1 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4435) IncA PF04156.9 ETO07983.1 - 0.0048 16.5 14.1 0.007 15.9 9.8 1.3 1 0 0 1 1 1 1 IncA protein TMPIT PF07851.8 ETO07983.1 - 0.13 11.3 17.3 0.072 12.1 1.6 2.2 1 1 1 2 2 2 0 TMPIT-like protein Ribosomal_L22 PF00237.14 ETO07983.1 - 0.16 11.9 1.1 3.3 7.7 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L22p/L17e V_ATPase_I PF01496.14 ETO07983.1 - 0.17 9.6 15.9 0.43 8.3 11.0 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 ETO07983.1 - 0.21 10.5 10.4 0.31 9.9 7.2 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Laminin_II PF06009.7 ETO07983.1 - 0.44 10.2 9.9 3.8 7.2 5.1 2.4 2 0 0 2 2 2 0 Laminin Domain II Histidinol_dh PF00815.15 ETO07983.1 - 0.62 8.6 2.7 1 7.9 1.9 1.3 1 0 0 1 1 1 0 Histidinol dehydrogenase TMF_TATA_bd PF12325.3 ETO07983.1 - 0.69 9.6 17.8 5.7 6.6 10.5 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Tup_N PF08581.5 ETO07983.1 - 0.82 9.9 19.4 0.1 12.7 9.2 2.6 3 0 0 3 3 3 0 Tup N-terminal DUF87 PF01935.12 ETO07983.1 - 1.2 8.8 8.8 0.79 9.4 4.6 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 APG6 PF04111.7 ETO07983.1 - 2.1 7.3 21.9 0.91 8.5 13.6 1.7 1 1 0 1 1 1 0 Autophagy protein Apg6 Fzo_mitofusin PF04799.8 ETO07983.1 - 2.6 7.3 12.7 0.18 11.1 5.0 2.0 3 0 0 3 3 3 0 fzo-like conserved region DSHCT PF08148.7 ETO07983.1 - 3 7.0 7.0 5.5 6.1 2.4 2.8 2 2 1 3 3 3 0 DSHCT (NUC185) domain Spectrin PF00435.16 ETO07983.1 - 4.5 7.6 19.4 6.4 7.1 10.4 3.0 2 1 2 4 4 4 0 Spectrin repeat MAPEG PF01124.13 ETO07984.1 - 4.9e-06 26.1 0.0 5.7e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 MAPEG family Pkinase PF00069.20 ETO07986.1 - 4.7e-26 91.5 0.0 8e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO07986.1 - 5.5e-19 68.2 0.0 8.3e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO07986.1 - 0.062 12.2 0.2 0.24 10.3 0.0 1.8 1 1 1 2 2 2 0 Kinase-like TRF PF08558.5 ETO07987.1 - 0.0014 17.9 0.4 0.0032 16.8 0.3 1.5 1 1 0 1 1 1 1 Telomere repeat binding factor (TRF) NACHT PF05729.7 ETO07989.1 - 2.3e-07 30.6 0.0 5.2e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETO07989.1 - 3.6e-06 27.0 0.1 0.00022 21.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 ETO07989.1 - 0.043 13.5 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 ETO07989.1 - 0.054 13.6 0.6 0.42 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 ETO07989.1 - 0.35 10.0 0.0 0.35 10.0 0.0 2.8 2 1 1 3 3 3 0 RecF/RecN/SMC N terminal domain DUF4363 PF14276.1 ETO07991.1 - 0.04 13.6 2.8 0.53 9.9 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Rho_Binding PF08912.6 ETO07992.1 - 0.025 14.8 0.9 0.025 14.8 0.6 1.7 2 0 0 2 2 2 0 Rho Binding PP1 PF07430.6 ETO07993.1 - 0.0092 15.5 4.5 0.016 14.7 3.1 1.3 1 0 0 1 1 1 1 Phloem filament protein PP1 WXG100 PF06013.7 ETO07995.1 - 0.24 11.4 2.9 0.32 11.0 0.0 2.5 3 1 0 3 3 3 0 Proteins of 100 residues with WXG DUF2115 PF09888.4 ETO07995.1 - 0.3 11.1 12.4 1.2 9.1 4.2 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) DASH_Dad1 PF08649.5 ETO07995.1 - 0.38 10.4 4.3 14 5.4 0.1 3.3 3 0 0 3 3 3 0 DASH complex subunit Dad1 Rapamycin_bind PF08771.6 ETO07995.1 - 4.3 7.4 8.5 15 5.7 0.2 2.8 3 0 0 3 3 3 0 Rapamycin binding domain Kelch_1 PF01344.20 ETO07996.1 - 4.2e-08 32.5 1.7 0.015 14.8 0.1 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO07996.1 - 6.5e-07 29.2 1.7 0.0042 17.2 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 ETO07996.1 - 0.00089 18.9 2.1 1.5 8.7 0.1 3.4 3 1 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 ETO07996.1 - 0.0037 17.4 1.1 0.65 10.2 0.0 3.4 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO07996.1 - 0.024 14.3 2.4 0.59 9.9 0.1 3.6 5 0 0 5 5 5 0 Galactose oxidase, central domain WD40 PF00400.27 ETO07997.1 - 2.6e-49 163.3 24.0 3.2e-12 45.8 0.2 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO07997.1 - 1.1e-08 33.6 1.7 0.11 10.6 0.0 4.6 3 1 1 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO07997.1 - 3.7e-06 25.9 7.7 0.58 8.8 0.0 4.3 1 1 2 3 3 3 3 Nup133 N terminal like Mad3_BUB1_II PF08171.6 ETO07997.1 - 0.039 13.8 0.6 0.085 12.7 0.4 1.6 1 1 0 1 1 1 0 Mad3/BUB1 homology region 2 DUF3942 PF13078.1 ETO07997.1 - 0.11 12.5 3.4 1.3 9.0 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3942) DUF1851 PF08906.6 ETO07998.1 - 0.12 12.3 0.4 0.18 11.7 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1851) AAA PF00004.24 ETO07999.1 - 0.0096 16.1 0.0 0.05 13.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) CobA_CobO_BtuR PF02572.10 ETO07999.1 - 0.026 14.1 0.0 0.086 12.4 0.0 1.9 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP AAA_22 PF13401.1 ETO07999.1 - 0.09 12.9 0.0 0.47 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Exo_endo_phos_2 PF14529.1 ETO08000.1 - 2.2e-16 59.5 0.6 3.3e-16 58.9 0.4 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 ETO08000.1 - 0.004 17.1 0.0 0.0047 16.8 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3626 PF12294.3 ETO08001.1 - 0.0039 16.2 0.8 0.0057 15.7 0.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3626) CsrA PF02599.11 ETO08001.1 - 0.5 10.1 3.9 1.3 8.8 2.7 1.7 1 0 0 1 1 1 0 Global regulator protein family bZIP_C PF12498.3 ETO08001.1 - 0.91 10.7 3.2 3.7 8.8 0.0 2.6 2 1 0 2 2 2 0 Basic leucine-zipper C terminal TnpV PF14198.1 ETO08001.1 - 1.1 9.1 6.5 4.7 7.1 0.1 2.5 2 1 1 3 3 3 0 Transposon-encoded protein TnpV DUF1283 PF06932.6 ETO08001.1 - 2 8.5 6.4 0.21 11.6 0.6 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1283) DUF1870 PF08965.5 ETO08001.1 - 2.8 7.6 8.3 0.46 10.1 1.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1870) APG5 PF04106.7 ETO08001.1 - 5.9 6.3 14.6 13 5.2 10.1 1.5 1 1 0 1 1 1 0 Autophagy protein Apg5 Kelch_6 PF13964.1 ETO08002.1 - 0.0042 17.1 0.0 0.44 10.8 0.0 2.7 2 0 0 2 2 2 1 Kelch motif Toprim PF01751.17 ETO08002.1 - 0.16 11.9 0.7 0.84 9.6 0.3 2.3 1 1 1 2 2 2 0 Toprim domain HEAT_2 PF13646.1 ETO08003.1 - 2.7e-05 24.3 0.0 0.0038 17.4 0.0 3.4 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.17 ETO08003.1 - 0.0065 16.4 0.0 2.6 8.3 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat Vac14_Fab1_bd PF12755.2 ETO08003.1 - 0.052 13.9 0.2 0.052 13.9 0.1 6.2 5 1 2 7 7 7 0 Vacuolar 14 Fab1-binding region DUF2538 PF10804.3 ETO08006.1 - 0.051 13.4 0.5 0.071 12.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2538) Exo_endo_phos_2 PF14529.1 ETO08007.1 - 0.0013 18.3 0.1 0.0013 18.3 0.1 2.7 2 1 1 3 3 3 1 Endonuclease-reverse transcriptase RGS PF00615.14 ETO08008.1 - 1.5e-06 28.3 0.0 2.7e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 Regulator of G protein signaling domain NYD-SP28_assoc PF14775.1 ETO08008.1 - 0.03 14.0 0.9 0.061 13.0 0.0 2.0 2 0 0 2 2 2 0 Sperm tail C-terminal domain WD40 PF00400.27 ETO08009.1 - 4.8e-07 29.4 1.0 5.9e-05 22.8 0.6 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat RVT_1 PF00078.22 ETO08010.1 - 3.6e-22 78.7 2.7 2.9e-13 49.6 0.1 2.9 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Kelch_2 PF07646.10 ETO08011.1 - 2.1e-08 33.6 1.0 0.0034 17.0 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO08011.1 - 6.8e-08 31.9 0.6 0.0033 16.9 0.0 4.3 4 1 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO08011.1 - 1e-07 31.8 0.7 0.031 14.4 0.0 4.3 4 1 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO08011.1 - 4.5e-05 23.1 0.4 0.27 11.0 0.0 3.7 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO08011.1 - 0.002 18.0 4.0 1.1 9.3 0.0 4.2 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO08012.1 - 0.086 12.4 0.2 2 8.0 0.0 2.8 3 0 0 3 3 3 0 Kelch motif Guanylate_cyc_2 PF09778.4 ETO08013.1 - 0.068 12.3 0.0 0.073 12.2 0.0 1.1 1 0 0 1 1 1 0 Guanylylate cyclase GPCR_chapero_1 PF11904.3 ETO08014.1 - 0.055 12.6 0.3 0.08 12.0 0.2 1.2 1 0 0 1 1 1 0 GPCR-chaperone WD40 PF00400.27 ETO08015.1 - 2.7e-119 385.2 51.7 8e-11 41.3 0.0 15.3 15 0 0 15 15 15 14 WD domain, G-beta repeat Pentapeptide_4 PF13599.1 ETO08015.1 - 6.6e-06 25.8 1.6 8.7e-05 22.2 0.4 2.6 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 ETO08015.1 - 9.2e-05 22.2 0.4 0.0036 17.1 0.2 2.8 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETO08015.1 - 0.0014 17.8 0.2 0.0028 16.8 0.2 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) PD40 PF07676.7 ETO08015.1 - 0.24 11.1 7.6 61 3.4 0.0 6.3 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 ETO08015.1 - 7.7 5.9 7.8 1.2e+02 2.0 0.0 5.1 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature VWA_2 PF13519.1 ETO08016.1 - 8.4e-08 32.5 0.0 1.1e-07 32.1 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 ETO08016.1 - 0.12 12.0 0.0 1.4 8.5 0.0 2.0 1 1 0 2 2 2 0 von Willebrand factor type A domain DUF1330 PF07045.6 ETO08017.1 - 0.085 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1330) Kelch_1 PF01344.20 ETO08018.1 - 5e-08 32.3 6.4 0.00055 19.4 0.8 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO08018.1 - 5.5e-07 29.2 0.4 0.0098 15.6 0.1 3.8 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO08018.1 - 0.00017 21.1 7.5 3.9 7.3 0.0 5.1 5 2 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 ETO08018.1 - 0.00085 19.3 2.5 13 6.1 0.0 4.4 4 0 0 4 4 4 1 Kelch motif Copper-bind PF00127.15 ETO08018.1 - 0.05 13.8 0.7 0.13 12.4 0.1 2.0 2 0 0 2 2 2 0 Copper binding proteins, plastocyanin/azurin family Kelch_5 PF13854.1 ETO08018.1 - 0.93 9.5 4.9 7 6.7 0.0 4.0 6 0 0 6 6 6 0 Kelch motif Fucose_iso_N2 PF07882.7 ETO08021.1 - 0.12 11.9 0.5 0.26 10.9 0.3 1.5 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain ABC_tran_2 PF12848.2 ETO08022.1 - 0.019 14.7 3.7 0.033 14.0 2.5 1.4 1 0 0 1 1 1 0 ABC transporter N-SET PF11764.3 ETO08022.1 - 0.073 12.9 3.2 0.12 12.2 2.2 1.3 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N FadA PF09403.5 ETO08022.1 - 0.25 11.3 4.6 0.12 12.3 1.0 1.9 2 0 0 2 2 2 0 Adhesion protein FadA Potex_coat PF06184.6 ETO08023.1 - 0.067 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Potexvirus coat protein Histone_HNS PF00816.16 ETO08023.1 - 0.31 11.5 5.0 0.59 10.6 3.2 1.7 1 1 0 1 1 1 0 H-NS histone family DUF3886 PF13025.1 ETO08023.1 - 0.68 9.9 13.9 0.25 11.3 1.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) DUF1465 PF07323.7 ETO08024.1 - 0.012 15.1 0.2 0.025 14.1 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1465) Myb_DNA-bind_5 PF13873.1 ETO08024.1 - 0.022 14.6 1.8 0.14 12.0 0.1 2.4 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain IncA PF04156.9 ETO08024.1 - 0.12 11.9 1.7 0.19 11.2 1.2 1.3 1 0 0 1 1 1 0 IncA protein MtrB PF05440.7 ETO08024.1 - 0.13 12.3 0.0 0.55 10.3 0.0 1.9 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B Sulfotransfer_1 PF00685.22 ETO08025.1 - 0.00025 20.3 2.1 0.00041 19.7 1.5 1.5 1 1 0 1 1 1 1 Sulfotransferase domain DUF3801 PF12687.2 ETO08025.1 - 0.0054 16.3 3.2 0.0054 16.3 2.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3801) Sulfotransfer_3 PF13469.1 ETO08025.1 - 0.07 14.0 0.0 1.6 9.6 0.0 2.2 1 1 0 1 1 1 0 Sulfotransferase family E7 PF00527.13 ETO08025.1 - 0.13 12.4 0.6 0.29 11.3 0.4 1.6 1 0 0 1 1 1 0 E7 protein, Early protein DUF2207 PF09972.4 ETO08026.1 - 0.0025 16.5 2.7 0.0028 16.2 1.9 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) PigN PF04987.9 ETO08026.1 - 0.0027 16.4 1.5 0.0037 15.9 1.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) DUF3784 PF12650.2 ETO08026.1 - 0.022 14.6 5.0 0.022 14.6 3.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF4173 PF13777.1 ETO08026.1 - 0.028 13.7 2.3 0.033 13.4 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) SdpI PF13630.1 ETO08026.1 - 0.035 13.8 8.0 0.071 12.8 5.5 1.5 1 0 0 1 1 1 0 SdpI/YhfL protein family DUF2919 PF11143.3 ETO08026.1 - 0.54 10.0 4.4 4.2 7.1 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2919) CDC50 PF03381.10 ETO08026.1 - 0.67 9.0 7.3 1.1 8.3 0.7 2.4 1 1 1 2 2 2 0 LEM3 (ligand-effect modulator 3) family / CDC50 family Pox_LP_H2 PF03356.10 ETO08026.1 - 1 9.0 8.5 2 8.0 1.5 2.5 1 1 1 2 2 2 0 Viral late protein H2 SUR7 PF06687.7 ETO08026.1 - 1.2 8.6 6.7 0.89 9.0 3.1 1.9 1 1 1 2 2 2 0 SUR7/PalI family WD40 PF00400.27 ETO08027.1 - 7.5e-33 111.2 1.1 8.1e-11 41.3 0.3 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO08027.1 - 0.0001 22.2 0.1 0.0042 17.2 0.0 3.6 3 0 0 3 3 3 1 Kelch motif Cytochrom_D1 PF02239.11 ETO08027.1 - 0.0022 16.3 0.1 0.29 9.3 0.1 3.0 2 1 0 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO08027.1 - 0.009 14.7 8.1 0.89 8.2 3.5 3.5 1 1 1 2 2 2 2 Nup133 N terminal like GUB_WAK_bind PF13947.1 ETO08029.1 - 0.043 14.3 1.6 0.052 14.0 0.2 1.7 1 1 1 2 2 2 0 Wall-associated receptor kinase galacturonan-binding TMEM171 PF15471.1 ETO08030.1 - 0.048 12.4 0.7 0.085 11.6 0.5 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 Wzy_C PF04932.10 ETO08030.1 - 0.1 12.3 0.4 0.17 11.6 0.3 1.3 1 0 0 1 1 1 0 O-Antigen ligase Sec66 PF09802.4 ETO08030.1 - 0.12 11.8 1.7 0.14 11.4 0.0 1.8 2 0 0 2 2 2 0 Preprotein translocase subunit Sec66 OTU PF02338.14 ETO08031.1 - 0.019 15.5 0.7 0.063 13.8 0.4 1.8 1 1 1 2 2 2 0 OTU-like cysteine protease Mg_trans_NIPA PF05653.9 ETO08033.1 - 8.7e-11 41.3 3.1 1.2e-10 40.8 2.1 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA DUF3021 PF11457.3 ETO08033.1 - 0.12 12.3 6.5 0.47 10.3 4.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) PgaD PF13994.1 ETO08033.1 - 3.9 6.9 7.3 0.31 10.5 0.8 2.2 1 1 2 3 3 3 0 PgaD-like protein WD40 PF00400.27 ETO08034.1 - 0.0021 17.8 0.1 0.0067 16.2 0.1 1.9 1 0 0 1 1 1 1 WD domain, G-beta repeat ETRAMP PF09716.5 ETO08034.1 - 0.092 12.7 6.1 0.26 11.2 4.2 1.8 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Peptidase_C14 PF00656.17 ETO08035.1 - 0.00094 18.9 0.1 0.0013 18.5 0.0 1.3 1 1 0 1 1 1 1 Caspase domain COX14 PF14880.1 ETO08035.1 - 0.36 10.4 1.6 0.84 9.3 1.1 1.6 1 1 0 1 1 1 0 Cytochrome oxidase c assembly Peptidase_C14 PF00656.17 ETO08036.1 - 0.00084 19.1 0.1 0.0014 18.3 0.1 1.4 1 0 0 1 1 1 1 Caspase domain DUF258 PF03193.11 ETO08037.1 - 0.074 12.2 1.5 0.13 11.4 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IncA PF04156.9 ETO08037.1 - 5.8 6.4 8.7 9.4 5.7 6.0 1.3 1 0 0 1 1 1 0 IncA protein DUF2457 PF10446.4 ETO08038.1 - 0.00072 18.4 22.3 0.00072 18.4 15.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) BSP_II PF05432.6 ETO08038.1 - 0.0056 15.9 9.6 0.0095 15.2 6.6 1.3 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) BLVR PF06375.6 ETO08038.1 - 0.006 16.4 8.5 0.006 16.4 5.9 2.3 2 1 0 2 2 2 1 Bovine leukaemia virus receptor (BLVR) RXT2_N PF08595.6 ETO08038.1 - 0.0087 15.8 11.3 0.0087 15.8 7.8 1.9 2 1 0 2 2 2 1 RXT2-like, N-terminal Herpes_env PF01673.13 ETO08038.1 - 0.0089 14.6 1.2 0.013 14.0 0.8 1.2 1 0 0 1 1 1 1 Herpesvirus putative major envelope glycoprotein Zip PF02535.17 ETO08038.1 - 0.012 14.6 0.8 0.012 14.6 0.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Myc_N PF01056.13 ETO08038.1 - 0.027 13.6 3.9 0.049 12.8 2.7 1.5 1 0 0 1 1 1 0 Myc amino-terminal region Serinc PF03348.10 ETO08038.1 - 0.056 12.1 0.8 0.075 11.7 0.6 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Radial_spoke PF04712.7 ETO08038.1 - 0.22 10.2 8.5 0.031 13.0 1.9 1.8 2 0 0 2 2 2 0 Radial spokehead-like protein Trypan_PARP PF05887.6 ETO08038.1 - 0.28 11.0 3.6 0.45 10.3 2.5 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3987 PF13148.1 ETO08038.1 - 0.54 8.7 3.6 0.93 7.9 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) ETRAMP PF09716.5 ETO08038.1 - 0.62 10.0 5.6 0.14 12.1 1.1 1.9 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF4094 PF13334.1 ETO08038.1 - 0.68 10.3 4.6 0.44 10.9 0.6 2.4 2 2 1 3 3 3 0 Domain of unknown function (DUF4094) FYDLN_acid PF09538.5 ETO08038.1 - 0.79 10.3 21.0 0.086 13.4 9.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Sporozoite_P67 PF05642.6 ETO08038.1 - 0.89 7.3 8.2 1.2 6.9 5.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.7 ETO08038.1 - 1.6 6.5 25.7 1.4 6.7 0.6 2.0 2 0 0 2 2 2 0 Nop14-like family Vfa1 PF08432.5 ETO08038.1 - 2.7 7.9 19.9 1.8 8.5 9.1 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Rubis-subs-bind PF09273.6 ETO08038.1 - 2.8 7.8 7.6 0.32 10.9 0.3 2.2 2 1 0 2 2 2 0 Rubisco LSMT substrate-binding SR-25 PF10500.4 ETO08038.1 - 3.6 7.0 14.7 0.2 11.0 4.6 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein S-antigen PF05756.6 ETO08038.1 - 4.8 7.2 17.4 0.11 12.5 6.8 2.0 2 1 0 2 2 2 0 S-antigen protein DUF1168 PF06658.7 ETO08038.1 - 4.8 6.6 20.5 0.31 10.5 8.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) BUD22 PF09073.5 ETO08038.1 - 5.9 5.8 24.6 0.23 10.4 11.6 1.9 2 0 0 2 2 2 0 BUD22 NOA36 PF06524.7 ETO08038.1 - 6.6 5.8 19.4 0.25 10.5 9.4 1.6 2 0 0 2 2 2 0 NOA36 protein Pox_Ag35 PF03286.9 ETO08038.1 - 7.5 6.0 24.1 0.15 11.6 10.1 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Peptidase_S49_N PF08496.5 ETO08039.1 - 1e-05 25.3 4.4 1.1e-05 25.2 3.1 1.0 1 0 0 1 1 1 1 Peptidase family S49 N-terminal OmpH PF03938.9 ETO08039.1 - 0.00015 21.7 4.5 0.00021 21.2 3.1 1.2 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) TMF_TATA_bd PF12325.3 ETO08039.1 - 0.0013 18.4 17.8 0.036 13.8 6.7 2.1 1 1 1 2 2 2 2 TATA element modulatory factor 1 TATA binding DUF1342 PF07072.6 ETO08039.1 - 0.004 16.8 6.7 0.004 16.8 4.6 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1342) Spc7 PF08317.6 ETO08039.1 - 0.0041 15.8 19.2 0.0098 14.5 12.4 1.7 1 1 1 2 2 2 1 Spc7 kinetochore protein DUF3610 PF12272.3 ETO08039.1 - 0.013 15.1 4.1 0.013 15.1 2.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3610) WEMBL PF05701.6 ETO08039.1 - 0.015 13.8 16.0 0.018 13.5 11.1 1.0 1 0 0 1 1 1 0 Weak chloroplast movement under blue light TPR_MLP1_2 PF07926.7 ETO08039.1 - 0.029 14.1 17.5 0.33 10.6 11.7 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein AKNA PF12443.3 ETO08039.1 - 0.031 14.2 12.8 0.029 14.3 5.2 2.0 1 1 1 2 2 2 0 AT-hook-containing transcription factor TMPIT PF07851.8 ETO08039.1 - 0.036 13.1 10.1 0.055 12.5 7.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF3573 PF12097.3 ETO08039.1 - 0.036 12.6 2.8 0.044 12.4 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Vfa1 PF08432.5 ETO08039.1 - 0.049 13.6 13.0 0.064 13.2 9.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Phage_GPO PF05929.6 ETO08039.1 - 0.063 12.5 6.5 0.076 12.2 4.5 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4201 PF13870.1 ETO08039.1 - 0.086 12.2 21.0 0.48 9.8 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) TcdA_TcdB PF12919.2 ETO08039.1 - 0.11 10.9 9.3 0.13 10.7 6.4 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Atg14 PF10186.4 ETO08039.1 - 0.13 11.1 15.3 0.16 10.9 10.6 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Bacillus_HBL PF05791.6 ETO08039.1 - 0.16 11.3 9.9 0.33 10.3 6.7 1.6 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Reo_sigmaC PF04582.7 ETO08039.1 - 0.17 11.0 0.6 0.19 10.8 0.4 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein RTBV_P46 PF06216.6 ETO08039.1 - 0.2 10.4 10.8 0.043 12.6 0.5 2.0 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein TMEM237 PF15383.1 ETO08039.1 - 0.21 10.6 3.6 0.31 10.1 2.5 1.2 1 0 0 1 1 1 0 Transmembrane protein 237 Glyco_hydro_67N PF03648.9 ETO08039.1 - 0.24 11.4 2.9 0.23 11.5 0.5 1.8 1 1 1 2 2 2 0 Glycosyl hydrolase family 67 N-terminus IncA PF04156.9 ETO08039.1 - 0.28 10.7 18.8 2.7 7.5 6.8 2.1 1 1 1 2 2 2 0 IncA protein DUF3810 PF12725.2 ETO08039.1 - 0.39 9.5 5.2 0.55 9.0 3.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) BCAS2 PF05700.6 ETO08039.1 - 0.48 9.8 13.5 0.6 9.5 9.4 1.1 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) Bcr-Abl_Oligo PF09036.5 ETO08039.1 - 0.51 10.3 5.4 10 6.1 0.9 2.4 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain COG2 PF06148.6 ETO08039.1 - 0.51 10.2 9.3 0.55 10.0 5.1 1.8 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Mac PF12464.3 ETO08039.1 - 0.51 10.3 6.1 1.1 9.3 1.4 2.7 1 1 1 2 2 2 0 Maltose acetyltransferase Fib_alpha PF08702.5 ETO08039.1 - 0.61 10.2 9.4 0.76 9.8 6.5 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF349 PF03993.7 ETO08039.1 - 0.63 10.2 9.0 0.86 9.8 1.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) DUF724 PF05266.9 ETO08039.1 - 0.65 9.5 18.6 1.4 8.4 5.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) M PF02370.11 ETO08039.1 - 0.66 10.5 0.1 0.66 10.5 0.1 3.6 3 2 0 3 3 1 0 M protein repeat IL5 PF02025.10 ETO08039.1 - 0.69 9.9 3.8 13 5.8 0.4 2.3 1 1 1 2 2 2 0 Interleukin 5 Mnd1 PF03962.10 ETO08039.1 - 0.8 9.3 17.3 1.6 8.3 11.6 1.6 1 1 1 2 2 2 0 Mnd1 family DUF972 PF06156.8 ETO08039.1 - 0.99 9.7 14.7 1.5 9.2 7.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF1640 PF07798.6 ETO08039.1 - 1.1 9.2 14.7 1.5 8.8 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) SlyX PF04102.7 ETO08039.1 - 1.1 9.6 7.1 3.3 8.1 0.4 2.7 1 1 2 3 3 3 0 SlyX THOC7 PF05615.8 ETO08039.1 - 1.3 9.3 18.8 4 7.6 9.7 2.1 1 1 1 2 2 2 0 Tho complex subunit 7 DUF904 PF06005.7 ETO08039.1 - 1.3 9.3 20.9 1.8 8.9 4.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF904) YMF19 PF02326.10 ETO08039.1 - 1.3 9.6 15.2 10 6.7 10.5 2.2 1 1 0 1 1 1 0 Plant ATP synthase F0 APG6 PF04111.7 ETO08039.1 - 1.4 7.8 15.3 2.2 7.2 10.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4446 PF14584.1 ETO08039.1 - 1.4 8.6 7.2 0.62 9.8 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) ATG16 PF08614.6 ETO08039.1 - 1.5 8.5 18.1 12 5.6 12.5 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF342 PF03961.8 ETO08039.1 - 1.5 7.1 14.0 2.1 6.6 9.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1202 PF06717.6 ETO08039.1 - 1.7 7.8 10.5 1.4 8.0 4.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1202) ADIP PF11559.3 ETO08039.1 - 2.1 8.2 19.0 5.6 6.8 6.8 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TMEM192 PF14802.1 ETO08039.1 - 2.4 6.9 6.0 3.3 6.5 4.1 1.1 1 0 0 1 1 1 0 TMEM192 family GrpE PF01025.14 ETO08039.1 - 4.3 6.8 17.1 0.55 9.7 4.9 2.0 1 1 1 2 2 2 0 GrpE DUF3552 PF12072.3 ETO08039.1 - 4.4 6.4 19.6 8.2 5.5 13.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Syntaxin PF00804.20 ETO08039.1 - 5 7.3 15.1 7.3 6.8 10.4 1.3 1 0 0 1 1 1 0 Syntaxin Prefoldin_2 PF01920.15 ETO08039.1 - 6.8 6.5 18.8 0.31 10.8 5.7 2.6 1 1 1 2 2 2 0 Prefoldin subunit DUF4407 PF14362.1 ETO08039.1 - 7.5 5.4 8.2 14 4.5 5.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ALMT PF11744.3 ETO08039.1 - 8.1 4.9 7.8 10 4.6 5.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4200 PF13863.1 ETO08039.1 - 8.4 6.3 24.4 16 5.4 2.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) FWWh PF14922.1 ETO08040.1 - 0.00019 20.9 0.0 0.00019 20.9 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function Ax_dynein_light PF10211.4 ETO08040.1 - 0.0075 16.1 7.5 0.011 15.5 5.2 1.2 1 0 0 1 1 1 1 Axonemal dynein light chain DUF3450 PF11932.3 ETO08040.1 - 0.032 13.4 4.3 0.049 12.8 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ERM PF00769.14 ETO08040.1 - 0.11 12.0 10.5 0.15 11.5 7.3 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family YlqD PF11068.3 ETO08040.1 - 0.24 11.4 8.6 0.11 12.5 4.4 1.5 2 0 0 2 2 2 0 YlqD protein PRTase_1 PF11202.3 ETO08040.1 - 0.25 10.2 1.8 0.4 9.6 1.3 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase (PRTase) AHH PF14412.1 ETO08040.1 - 0.28 11.1 1.8 9.3 6.2 0.1 2.2 2 0 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH CENP-H PF05837.7 ETO08040.1 - 1.1 9.4 7.3 2.4 8.3 5.1 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) IncA PF04156.9 ETO08040.1 - 1.4 8.5 6.9 2.2 7.8 4.8 1.2 1 0 0 1 1 1 0 IncA protein XisI PF08869.6 ETO08041.1 - 0.029 14.5 0.6 0.052 13.6 0.1 1.7 1 1 1 2 2 2 0 XisI protein DUF3106 PF11304.3 ETO08043.1 - 0.0016 18.8 3.6 0.0021 18.4 2.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3106) Flexi_CP PF00286.15 ETO08043.1 - 0.061 13.0 0.1 0.083 12.5 0.1 1.2 1 0 0 1 1 1 0 Viral coat protein DUF2899 PF11449.3 ETO08043.1 - 0.15 11.2 0.8 0.4 9.8 0.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2899) DUF1775 PF07987.6 ETO08043.1 - 0.2 11.4 1.5 0.26 11.1 1.1 1.1 1 0 0 1 1 1 0 Domain of unkown function (DUF1775) DUF2924 PF11149.3 ETO08043.1 - 0.25 11.3 2.8 1.1 9.3 1.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2924) SieB PF14163.1 ETO08043.1 - 0.76 9.3 7.8 0.07 12.7 0.8 2.1 2 0 0 2 2 2 0 Superinfection exclusion protein B ZYG-11_interact PF05884.7 ETO08043.1 - 2.1 7.3 6.5 3.9 6.4 4.5 1.5 1 1 0 1 1 1 0 Interactor of ZYG-11 DUF2547 PF10818.3 ETO08043.1 - 3.1 8.4 8.7 1.7 9.3 3.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2547) PC_rep PF01851.17 ETO08044.1 - 2.1e-06 27.6 10.0 0.0001 22.2 0.0 4.0 4 1 1 5 5 5 2 Proteasome/cyclosome repeat Pox_Ag35 PF03286.9 ETO08045.1 - 0.055 12.9 0.0 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAT PF02259.18 ETO08046.1 - 0.0063 15.5 2.1 0.0076 15.2 1.5 1.0 1 0 0 1 1 1 1 FAT domain Salp15 PF12115.3 ETO08046.1 - 0.096 12.9 2.5 0.17 12.1 1.5 1.7 1 1 0 1 1 1 0 Salivary protein of 15kDa inhibits CD4+ T cell activation TPR_21 PF09976.4 ETO08046.1 - 0.19 11.6 1.5 0.28 11.1 0.7 1.4 1 1 0 1 1 1 0 Tetratricopeptide repeat Apc3 PF12895.2 ETO08046.1 - 0.89 9.7 4.3 5.9 7.0 2.2 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF1712 PF08217.6 ETO08047.1 - 0.013 13.8 1.1 0.016 13.5 0.7 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1712) DUF3139 PF11337.3 ETO08047.1 - 0.12 12.6 2.3 0.22 11.7 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) Fis1_TPR_N PF14852.1 ETO08047.1 - 0.32 10.3 1.4 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Fis1 N-terminal tetratricopeptide repeat PRKCSH PF07915.8 ETO08048.1 - 2.8e-13 50.4 1.0 2.9e-08 34.4 0.1 2.8 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein ArsD PF06953.6 ETO08049.1 - 0.033 14.3 0.6 0.26 11.4 0.0 2.0 2 0 0 2 2 2 0 Arsenical resistance operon trans-acting repressor ArsD SAE2 PF08573.5 ETO08049.1 - 3.2 8.5 6.2 8 7.2 4.0 1.9 1 1 1 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus C2-set PF05790.10 ETO08049.1 - 6.6 6.7 8.3 5.2 7.1 0.6 3.0 1 1 1 2 2 2 0 Immunoglobulin C2-set domain RNA_pol_Rpb8 PF03870.10 ETO08050.1 - 0.021 14.9 0.6 0.025 14.7 0.4 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb8 DUF70 PF01901.11 ETO08050.1 - 7.1 5.5 8.4 10 5.0 5.8 1.3 1 1 0 1 1 1 0 Protein of unknown function DUF70 Med3 PF11593.3 ETO08051.1 - 0.071 12.3 2.7 0.066 12.4 1.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Stanniocalcin PF03298.8 ETO08052.1 - 0.039 12.9 0.5 0.07 12.1 0.3 1.4 1 0 0 1 1 1 0 Stanniocalcin family Activator-TraM PF11657.3 ETO08053.1 - 0.0086 15.5 0.1 0.025 14.0 0.1 1.8 1 1 0 1 1 1 1 Transcriptional activator TraM SF-assemblin PF06705.6 ETO08053.1 - 0.015 14.4 11.4 0.22 10.6 3.1 2.9 1 1 1 3 3 3 0 SF-assemblin/beta giardin DUF1104 PF06518.6 ETO08053.1 - 0.16 12.0 3.4 18 5.5 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1104) Spb1_C PF07780.7 ETO08053.1 - 0.19 11.1 2.1 17 4.8 0.0 3.0 3 0 0 3 3 3 0 Spb1 C-terminal domain Aida_N PF08910.5 ETO08053.1 - 1.3 9.3 6.4 21 5.4 0.3 3.7 2 1 2 4 4 4 0 Aida N-terminus OppC_N PF12911.2 ETO08054.1 - 7.2 6.0 8.3 28 4.1 2.9 2.5 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C WD40 PF00400.27 ETO08055.1 - 6.1e-62 203.4 23.3 1e-09 37.8 0.3 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO08055.1 - 3e-10 38.8 4.4 0.00051 18.3 0.6 4.7 1 1 2 4 4 4 3 Nucleoporin Nup120/160 SAB PF04382.8 ETO08055.1 - 0.0012 18.5 4.0 0.0022 17.6 0.8 2.5 2 0 0 2 2 2 1 SAB domain PV-1 PF06637.6 ETO08055.1 - 0.035 12.6 11.0 0.057 11.9 7.6 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) IncA PF04156.9 ETO08055.1 - 0.23 11.0 23.7 0.22 11.0 15.2 1.9 1 1 0 1 1 1 0 IncA protein DUF641 PF04859.7 ETO08055.1 - 0.96 9.2 15.5 0.2 11.4 5.8 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) HrpB7 PF09486.5 ETO08055.1 - 1.1 9.1 7.2 2.1 8.2 5.0 1.5 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF3450 PF11932.3 ETO08055.1 - 1.2 8.3 14.8 2.5 7.2 9.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Spc7 PF08317.6 ETO08055.1 - 1.8 7.1 28.3 12 4.4 19.6 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein Med4 PF10018.4 ETO08055.1 - 3.2 7.1 22.1 0.035 13.4 7.4 2.2 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Med9 PF07544.8 ETO08055.1 - 7.1 6.4 17.9 1.6 8.5 3.7 2.7 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 AAA_27 PF13514.1 ETO08055.1 - 8.5 3.9 19.2 11 3.5 13.3 1.1 1 0 0 1 1 1 0 AAA domain E1_DerP2_DerF2 PF02221.10 ETO08056.1 - 0.061 13.5 2.0 0.072 13.3 1.4 1.2 1 0 0 1 1 1 0 ML domain DUF4050 PF13259.1 ETO08056.1 - 0.2 11.5 6.3 0.37 10.7 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) AbiH PF14253.1 ETO08056.1 - 1 8.9 15.1 2.9 7.4 10.4 1.6 1 1 0 1 1 1 0 Bacteriophage abortive infection AbiH zf-C3HC4_2 PF13923.1 ETO08057.1 - 0.00026 20.9 2.6 0.0025 17.8 0.2 3.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO08057.1 - 0.0004 20.1 3.6 0.00044 20.0 0.6 2.4 2 0 0 2 2 2 1 Ring finger domain Plant_NMP1 PF06694.6 ETO08057.1 - 0.049 12.5 1.1 0.079 11.8 0.7 1.3 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) Cation_efflux PF01545.16 ETO08058.1 - 0.00037 19.6 13.6 0.00082 18.5 9.4 1.7 1 1 0 1 1 1 1 Cation efflux family DUF4271 PF14093.1 ETO08058.1 - 0.021 14.4 1.6 0.034 13.8 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) DUF3995 PF13160.1 ETO08058.1 - 0.15 12.1 1.5 0.52 10.3 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3995) DUF3784 PF12650.2 ETO08058.1 - 0.59 10.1 3.7 2.1 8.3 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3784) Apis_Csd PF11671.3 ETO08059.1 - 0.00057 19.7 13.0 0.00057 19.7 9.0 2.7 3 1 1 4 4 4 1 Complementary sex determiner protein DUF92 PF01940.11 ETO08060.1 - 0.14 11.3 0.2 1 8.4 0.1 2.0 2 0 0 2 2 2 0 Integral membrane protein DUF92 PDR_CDR PF06422.7 ETO08060.1 - 0.15 11.7 3.7 0.33 10.6 0.1 2.5 2 1 0 2 2 2 0 CDR ABC transporter Reticulon PF02453.12 ETO08060.1 - 0.22 11.1 3.1 0.91 9.1 0.4 2.2 2 0 0 2 2 2 0 Reticulon DUF4131 PF13567.1 ETO08060.1 - 0.23 10.8 6.1 0.33 10.3 0.0 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) DUF4455 PF14643.1 ETO08060.1 - 0.41 9.2 5.8 0.22 10.1 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4455) WD40 PF00400.27 ETO08061.1 - 0.0022 17.7 0.7 0.0038 17.0 0.2 1.6 2 0 0 2 2 2 1 WD domain, G-beta repeat WD40 PF00400.27 ETO08062.1 - 2.2e-11 43.1 1.5 5e-11 42.0 0.5 2.1 2 0 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO08062.1 - 0.00011 20.5 0.1 0.00017 19.8 0.1 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 TRAM_LAG1_CLN8 PF03798.11 ETO08062.1 - 0.048 13.2 3.0 0.061 12.8 2.1 1.2 1 0 0 1 1 1 0 TLC domain DUF1958 PF09211.5 ETO08062.1 - 0.055 13.5 0.4 0.14 12.2 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1958) Flu_PB1 PF00602.12 ETO08064.1 - 0.028 12.1 0.6 0.029 12.0 0.4 1.0 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB1 RNB PF00773.14 ETO08065.1 - 5.8e-94 315.0 0.8 6e-93 311.6 0.0 2.1 2 0 0 2 2 2 1 RNB domain PIN_4 PF13638.1 ETO08065.1 - 0.08 13.0 0.1 0.08 13.0 0.1 2.7 2 1 0 2 2 2 0 PIN domain Exonuc_VII_L PF02601.10 ETO08065.1 - 0.36 9.9 4.2 0.62 9.2 2.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit MatE PF01554.13 ETO08066.1 - 3.3e-24 85.3 20.7 7.9e-20 71.1 5.2 3.5 2 1 1 3 3 3 3 MatE Tubulin_C PF03953.12 ETO08067.1 - 4.5e-18 65.4 0.0 6e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Tubulin C-terminal domain WD40 PF00400.27 ETO08068.1 - 1.2e-58 193.0 25.8 1.7e-11 43.4 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO08068.1 - 2.5e-07 30.6 0.6 0.019 14.7 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO08068.1 - 0.0035 15.5 2.7 0.26 9.3 0.0 3.8 2 2 2 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO08068.1 - 0.045 12.0 0.0 0.93 7.7 0.0 2.8 2 1 1 3 3 3 0 Cytochrome D1 heme domain WD40 PF00400.27 ETO08069.1 - 1.8e-61 201.9 23.3 1.4e-11 43.7 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO08069.1 - 2.4e-14 52.4 4.6 6.7e-05 21.2 0.1 5.4 2 1 3 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO08069.1 - 0.00037 19.3 12.3 0.014 14.1 0.7 4.3 1 1 2 3 3 3 2 Nup133 N terminal like DUF1900 PF08954.6 ETO08069.1 - 0.077 12.5 0.3 4.1 6.9 0.0 3.4 3 2 2 5 5 5 0 Domain of unknown function (DUF1900) RabGAP-TBC PF00566.13 ETO08070.1 - 1.6e-50 171.5 2.5 1.6e-50 171.5 1.7 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain WD40 PF00400.27 ETO08071.1 - 4e-21 74.0 7.3 9.8e-09 34.7 0.8 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat zf-TRAF PF02176.13 ETO08071.1 - 2.9e-05 24.3 1.1 2.9e-05 24.3 0.8 3.2 3 0 0 3 3 3 1 TRAF-type zinc finger Nup160 PF11715.3 ETO08071.1 - 5.5e-05 21.4 2.9 0.0027 15.9 0.3 2.1 1 1 0 2 2 2 2 Nucleoporin Nup120/160 zf-C3HC4_2 PF13923.1 ETO08071.1 - 0.033 14.2 1.0 0.033 14.2 0.7 4.4 4 2 1 5 5 5 0 Zinc finger, C3HC4 type (RING finger) IPP-2 PF04979.9 ETO08072.1 - 0.056 13.6 0.5 0.096 12.9 0.0 1.5 2 0 0 2 2 2 0 Protein phosphatase inhibitor 2 (IPP-2) WD40 PF00400.27 ETO08073.1 - 4.7e-38 127.7 13.8 6.9e-12 44.7 0.2 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO08073.1 - 1.7e-10 39.6 3.7 0.00034 18.8 0.1 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO08073.1 - 0.00051 19.7 0.4 6.7 6.5 0.0 3.1 1 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region DUF4221 PF13970.1 ETO08073.1 - 0.079 12.2 4.5 0.35 10.1 0.1 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4221) USP7_C2 PF14533.1 ETO08073.1 - 0.088 12.2 0.5 12 5.2 0.0 2.7 1 1 2 3 3 3 0 Ubiquitin-specific protease C-terminal DUF1914 PF08932.5 ETO08073.1 - 0.29 11.1 2.3 2 8.4 0.4 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF1914) DUF2559 PF10832.3 ETO08073.1 - 1.4 8.7 3.9 16 5.4 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2559) Ribosomal_L50 PF10501.4 ETO08074.1 - 0.0034 17.3 0.4 0.0034 17.3 0.3 1.9 3 0 0 3 3 3 1 Ribosomal subunit 39S SNF2_N PF00176.18 ETO08074.1 - 0.14 10.9 2.3 0.17 10.6 1.6 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain MCC-bdg_PDZ PF10506.4 ETO08074.1 - 0.24 11.2 2.9 2.4 8.0 0.2 2.3 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Glyco_transf_8 PF01501.15 ETO08074.1 - 2 7.6 7.9 3.9 6.7 5.5 1.6 1 1 0 1 1 1 0 Glycosyl transferase family 8 IncA PF04156.9 ETO08074.1 - 5.1 6.6 10.2 7.5 6.1 7.1 1.2 1 0 0 1 1 1 0 IncA protein Nop53 PF07767.6 ETO08075.1 - 0.00037 19.6 2.3 0.00047 19.2 1.6 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF2197 PF09963.4 ETO08075.1 - 0.067 13.1 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-DHHC PF01529.15 ETO08075.1 - 0.16 11.3 3.9 0.9 8.9 0.0 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase CENP-T PF15511.1 ETO08075.1 - 8.1 5.5 16.2 9.3 5.3 11.2 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Kelch_6 PF13964.1 ETO08078.1 - 0.0098 16.0 4.4 0.017 15.2 0.0 3.3 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.20 ETO08078.1 - 0.045 13.2 4.7 0.072 12.6 0.2 3.1 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.1 ETO08078.1 - 0.1 12.3 0.0 2.6 7.9 0.0 2.9 2 1 0 2 2 2 0 Galactose oxidase, central domain WD40 PF00400.27 ETO08079.1 - 3.3e-80 261.3 19.0 1.4e-12 46.9 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO08079.1 - 1.8e-13 50.6 0.1 2.4e-06 27.3 0.0 4.1 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO08079.1 - 7e-11 41.5 9.1 0.47 10.1 0.1 6.5 6 0 0 6 6 6 4 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO08079.1 - 2.1e-05 24.6 0.2 0.12 12.7 0.0 4.0 4 0 0 4 4 4 1 Resistin Cytochrom_D1 PF02239.11 ETO08079.1 - 0.00014 20.2 0.3 0.25 9.5 0.1 2.6 1 1 2 3 3 3 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO08079.1 - 0.0002 20.8 0.7 0.033 13.6 0.5 3.1 1 1 1 2 2 2 2 PQQ-like domain Nup160 PF11715.3 ETO08079.1 - 0.00056 18.1 6.6 1.9 6.5 0.0 4.9 1 1 4 5 5 5 3 Nucleoporin Nup120/160 DHFR_2 PF06442.6 ETO08079.1 - 0.0015 18.1 0.1 0.91 9.2 0.0 3.1 2 0 0 2 2 2 2 R67 dihydrofolate reductase Nbas_N PF15492.1 ETO08079.1 - 0.013 14.6 0.9 1.1 8.3 0.1 3.2 1 1 3 4 4 4 0 Neuroblastoma-amplified sequence, N terminal DUF1258 PF06869.7 ETO08079.1 - 0.014 14.4 0.8 1.2 8.1 0.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1258) DUF727 PF05303.7 ETO08079.1 - 0.06 13.1 0.2 29 4.4 0.0 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF727) Proteasome_A_N PF10584.4 ETO08079.1 - 0.8 9.0 16.4 2.6 7.4 0.0 5.8 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature TBCC PF07986.7 ETO08081.1 - 5e-11 42.0 0.6 1.8e-10 40.2 0.4 2.0 1 0 0 1 1 1 1 Tubulin binding cofactor C Fzo_mitofusin PF04799.8 ETO08081.1 - 0.014 14.7 4.4 0.014 14.7 3.0 2.4 2 1 1 3 3 3 0 fzo-like conserved region PMC2NT PF08066.7 ETO08081.1 - 0.54 10.5 6.7 0.071 13.4 0.8 2.3 3 0 0 3 3 3 0 PMC2NT (NUC016) domain DUF972 PF06156.8 ETO08081.1 - 7.5 6.9 9.5 17 5.8 6.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) ubiquitin PF00240.18 ETO08083.1 - 6.8e-10 38.2 0.2 6.8e-10 38.2 0.1 2.3 3 0 0 3 3 3 1 Ubiquitin family Rad60-SLD PF11976.3 ETO08083.1 - 7e-07 28.8 0.2 2.9e-06 26.8 0.1 2.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UN_NPL4 PF11543.3 ETO08083.1 - 0.0033 17.6 0.0 0.0091 16.2 0.0 1.8 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 DUF3972 PF13118.1 ETO08083.1 - 0.0067 16.5 0.2 0.025 14.6 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3972) Telomere_reg-2 PF10193.4 ETO08083.1 - 0.026 14.7 0.1 0.12 12.6 0.0 2.1 2 0 0 2 2 2 0 Telomere length regulation protein DinB PF05163.7 ETO08083.1 - 0.052 13.2 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 DinB family Pneumo_matrix PF03393.11 ETO08083.1 - 0.071 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Pneumovirus matrix protein AATF-Che1 PF13339.1 ETO08083.1 - 0.25 11.5 11.5 0.071 13.2 1.0 3.4 3 1 0 3 3 3 0 Apoptosis antagonizing transcription factor IncA PF04156.9 ETO08083.1 - 0.78 9.2 4.6 0.17 11.4 0.6 1.8 2 0 0 2 2 2 0 IncA protein SlyX PF04102.7 ETO08083.1 - 0.85 10.0 6.2 0.15 12.4 0.5 2.4 2 0 0 2 2 2 0 SlyX DUF812 PF05667.6 ETO08084.1 - 0.022 13.3 5.1 0.021 13.3 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) MCC-bdg_PDZ PF10506.4 ETO08084.1 - 0.028 14.2 2.6 0.054 13.3 1.8 1.4 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF4140 PF13600.1 ETO08084.1 - 0.047 14.1 4.8 0.084 13.3 3.3 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 ETO08084.1 - 0.089 12.3 7.3 0.12 11.9 5.1 1.1 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 ETO08084.1 - 0.22 10.5 5.6 0.34 9.9 3.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 SprA-related PF12118.3 ETO08084.1 - 0.46 9.7 8.1 0.55 9.5 5.6 1.1 1 0 0 1 1 1 0 SprA-related family SspB PF04386.8 ETO08084.1 - 1.3 8.6 4.0 1.9 8.0 2.8 1.2 1 0 0 1 1 1 0 Stringent starvation protein B ATG16 PF08614.6 ETO08084.1 - 1.8 8.3 13.7 2.1 8.1 9.1 1.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Bap31 PF05529.7 ETO08084.1 - 2.8 7.3 9.5 4 6.8 6.6 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Sec62 PF03839.11 ETO08084.1 - 3.1 7.1 7.5 5.4 6.3 5.2 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DDHD PF02862.12 ETO08084.1 - 6.1 6.5 7.6 7.2 6.3 5.3 1.2 1 0 0 1 1 1 0 DDHD domain JmjC PF02373.17 ETO08085.1 - 2.2e-06 27.8 0.0 7.4e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 ETO08085.1 - 9.8e-06 25.2 0.1 4.9e-05 22.9 0.0 2.1 2 1 0 2 2 2 1 Cupin-like domain TPR_11 PF13414.1 ETO08085.1 - 0.00019 21.0 0.0 0.00042 19.9 0.0 1.7 1 0 0 1 1 1 1 TPR repeat TPR_19 PF14559.1 ETO08085.1 - 0.04 14.2 0.1 0.11 12.8 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4165 PF13752.1 ETO08086.1 - 0.031 14.0 0.5 0.084 12.6 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4165) MFS_1 PF07690.11 ETO08088.1 - 1.2e-43 149.1 31.8 4.4e-28 98.0 7.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETO08088.1 - 7.5e-10 37.9 21.2 3.5e-08 32.4 5.3 3.4 1 1 2 4 4 4 3 Sugar (and other) transporter MFS_3 PF05977.8 ETO08088.1 - 2.2e-05 22.7 21.0 0.00042 18.5 6.6 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector LacY_symp PF01306.14 ETO08088.1 - 0.021 13.3 9.3 0.021 13.3 3.1 2.1 2 0 0 2 2 2 0 LacY proton/sugar symporter Syja_N PF02383.13 ETO08089.1 - 0.037 12.7 2.7 0.046 12.4 1.9 1.1 1 0 0 1 1 1 0 SacI homology domain EF-hand_7 PF13499.1 ETO08090.1 - 1.3e-13 50.9 9.1 1.5e-08 34.5 1.3 2.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.1 ETO08090.1 - 4.1e-10 39.1 11.1 3.1e-06 26.6 1.2 3.6 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 ETO08090.1 - 6.2e-10 37.6 13.6 0.002 17.3 0.4 5.3 5 1 1 6 6 6 3 EF hand EF-hand_6 PF13405.1 ETO08090.1 - 3.9e-07 29.4 8.8 0.0013 18.4 0.8 5.1 5 1 1 6 6 6 2 EF-hand domain EF-hand_4 PF12763.2 ETO08090.1 - 0.00042 20.0 4.2 0.0048 16.6 0.5 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand TerB PF05099.8 ETO08090.1 - 0.0055 16.4 1.4 1.7 8.4 0.5 2.2 2 0 0 2 2 2 2 Tellurite resistance protein TerB SPARC_Ca_bdg PF10591.4 ETO08090.1 - 0.014 15.4 1.0 0.038 14.0 0.2 1.9 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.1 ETO08090.1 - 0.025 13.9 16.0 0.13 11.6 0.0 5.2 7 0 0 7 7 7 0 EF hand DUF3447 PF11929.3 ETO08095.1 - 0.025 14.3 4.4 0.044 13.5 1.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3447) RAI16-like PF10257.4 ETO08098.1 - 0.0094 14.9 0.1 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Pkinase PF00069.20 ETO08099.1 - 4.5e-34 117.7 0.7 9.7e-29 100.2 0.3 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO08099.1 - 2.6e-13 49.6 0.1 5.2e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO08099.1 - 0.029 13.4 0.4 0.11 11.5 0.1 1.9 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2576 PF10845.3 ETO08099.1 - 0.065 12.4 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) DUF3357 PF11837.3 ETO08101.1 - 0.00084 19.1 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) DUF1700 PF08006.6 ETO08101.1 - 0.001 18.3 3.4 0.0022 17.3 2.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1700) Baculo_11_kDa PF06143.6 ETO08101.1 - 0.0085 15.4 0.4 0.02 14.2 0.3 1.7 1 0 0 1 1 1 1 Baculovirus 11 kDa family ATP-synt_8 PF00895.15 ETO08101.1 - 0.065 13.4 0.1 0.2 11.9 0.0 1.9 1 1 0 1 1 1 0 ATP synthase protein 8 Brevenin PF03032.10 ETO08101.1 - 0.33 10.8 6.5 2.1 8.2 3.8 2.6 1 1 0 1 1 1 0 Brevenin/esculentin/gaegurin/rugosin family ETRAMP PF09716.5 ETO08101.1 - 3.8 7.5 10.4 0.25 11.3 1.4 2.8 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) ELFV_dehydrog PF00208.16 ETO08102.1 - 4.7e-23 82.0 0.6 5.2e-23 81.8 0.4 1.0 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase VPS9 PF02204.13 ETO08105.1 - 1e-10 41.5 0.5 6.2e-07 29.3 0.0 2.2 2 0 0 2 2 2 2 Vacuolar sorting protein 9 (VPS9) domain DUF4611 PF15387.1 ETO08105.1 - 0.073 13.2 1.3 0.14 12.3 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) BSP_II PF05432.6 ETO08106.1 - 0.046 12.9 0.2 0.092 12.0 0.1 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF3671 PF12420.3 ETO08106.1 - 1 9.3 0.0 1 9.3 0.0 3.4 3 1 0 3 3 3 0 Protein of unknown function WD40 PF00400.27 ETO08107.1 - 7e-29 98.6 0.2 4.1e-12 45.4 0.0 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO08107.1 - 6.5e-07 27.8 0.2 0.011 13.8 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO08107.1 - 0.00072 18.4 2.8 0.14 10.8 0.4 2.1 1 1 1 2 2 2 2 Nup133 N terminal like Hira PF07569.6 ETO08107.1 - 0.013 14.7 0.1 2.9 7.0 0.0 2.1 1 1 1 2 2 2 0 TUP1-like enhancer of split Coatomer_WDAD PF04053.9 ETO08107.1 - 0.014 14.2 0.8 0.018 13.8 0.6 1.1 1 0 0 1 1 1 0 Coatomer WD associated region PQQ_2 PF13360.1 ETO08107.1 - 0.017 14.5 0.0 0.044 13.2 0.0 1.6 1 1 0 1 1 1 0 PQQ-like domain Cytochrom_D1 PF02239.11 ETO08107.1 - 0.03 12.6 0.0 0.037 12.3 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain PDDEXK_1 PF12705.2 ETO08107.1 - 0.037 13.3 1.5 4.3 6.6 0.1 2.1 1 1 1 2 2 2 0 PD-(D/E)XK nuclease superfamily DUF3601 PF12208.3 ETO08107.1 - 0.072 13.0 0.2 0.93 9.4 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3601) WD40 PF00400.27 ETO08108.1 - 3.9e-56 185.0 27.5 3.1e-11 42.6 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO08108.1 - 2e-08 32.8 8.5 0.082 11.0 0.0 5.9 1 1 4 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO08108.1 - 9.5e-05 21.3 15.3 0.062 12.0 2.1 4.3 2 1 2 4 4 4 3 Nup133 N terminal like Bacillus_HBL PF05791.6 ETO08108.1 - 0.018 14.4 7.3 0.038 13.3 5.1 1.6 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF2461 PF09365.5 ETO08108.1 - 0.21 10.9 3.2 0.36 10.1 2.2 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein (DUF2461) DUF641 PF04859.7 ETO08108.1 - 0.23 11.2 7.6 0.37 10.5 5.3 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Spc7 PF08317.6 ETO08108.1 - 0.43 9.1 12.3 0.66 8.5 8.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_27 PF13514.1 ETO08108.1 - 2.4 5.7 8.6 3.3 5.2 5.9 1.1 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.4 ETO08108.1 - 3.7 6.4 13.7 5.6 5.8 9.5 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Bap31 PF05529.7 ETO08108.1 - 5.5 6.4 8.7 3.8 6.9 4.9 1.5 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like Borrelia_P83 PF05262.6 ETO08108.1 - 9 4.4 14.2 14 3.8 9.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DASH_Dam1 PF08653.5 ETO08109.1 - 0.046 13.4 5.1 1.6 8.5 0.1 3.2 3 0 0 3 3 3 0 DASH complex subunit Dam1 DUF4094 PF13334.1 ETO08109.1 - 0.087 13.2 10.2 0.18 12.2 1.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DUF4407 PF14362.1 ETO08109.1 - 1.4 7.7 6.0 2.4 7.0 4.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Uds1 PF15456.1 ETO08109.1 - 5.7 6.9 14.1 3.2 7.7 2.2 2.7 2 1 0 2 2 2 0 Up-regulated During Septation SecA_DEAD PF07517.9 ETO08110.1 - 5e-10 39.1 0.5 1.3e-09 37.7 0.0 1.9 2 0 0 2 2 2 1 SecA DEAD-like domain Helicase_C PF00271.26 ETO08110.1 - 0.00092 19.0 0.1 0.015 15.1 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain VWA_2 PF13519.1 ETO08110.1 - 0.016 15.3 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain UpxZ PF06603.6 ETO08110.1 - 0.017 15.1 1.0 0.48 10.4 0.0 3.2 4 0 0 4 4 4 0 UpxZ family of transcription anti-terminator antagonists ApoC-I PF04691.7 ETO08111.1 - 0.03 14.0 9.1 0.18 11.5 0.0 5.0 5 0 0 5 5 5 0 Apolipoprotein C-I (ApoC-1) RGS PF00615.14 ETO08111.1 - 0.16 12.0 18.9 0.64 10.1 4.6 3.9 2 2 0 2 2 2 0 Regulator of G protein signaling domain Spectrin PF00435.16 ETO08111.1 - 0.41 10.9 12.6 1.3 9.3 1.0 4.5 4 1 1 5 5 5 0 Spectrin repeat MMR_HSR1 PF01926.18 ETO08112.1 - 4.7e-05 23.3 1.5 0.00023 21.1 0.1 3.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 ETO08112.1 - 0.00015 21.0 5.1 0.00025 20.2 0.2 3.3 2 1 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 ETO08112.1 - 0.00036 20.8 0.1 0.00036 20.8 0.1 3.9 2 1 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 ETO08112.1 - 0.0065 15.9 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Miro PF08477.8 ETO08112.1 - 0.0067 16.9 2.2 0.24 11.8 0.0 4.0 3 0 0 3 3 3 1 Miro-like protein AAA_16 PF13191.1 ETO08112.1 - 0.11 12.4 0.6 0.81 9.6 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain AAA_19 PF13245.1 ETO08112.1 - 0.12 12.1 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 ETO08112.1 - 0.12 11.7 0.1 0.37 10.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 ETO08112.1 - 0.13 12.5 0.0 0.13 12.5 0.0 9.0 3 1 0 4 4 4 0 AAA domain SAM_1 PF00536.25 ETO08113.1 - 0.042 14.0 0.2 0.6 10.3 0.0 2.4 2 1 0 2 2 2 0 SAM domain (Sterile alpha motif) DUF633 PF04816.7 ETO08113.1 - 0.07 12.4 1.7 4.8 6.4 0.2 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF633) Xylanase PF13201.1 ETO08114.1 - 0.13 11.0 3.3 0.19 10.4 2.3 1.2 1 0 0 1 1 1 0 Putative glycoside hydrolase xylanase BamHI PF02923.10 ETO08115.1 - 0.1 12.5 0.4 0.12 12.2 0.3 1.2 1 0 0 1 1 1 0 Restriction endonuclease BamHI DUF2018 PF09442.5 ETO08115.1 - 0.68 10.5 3.5 5.8 7.5 1.2 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF2018) Methyltransf_11 PF08241.7 ETO08116.1 - 2.7e-14 53.4 0.0 5.5e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO08116.1 - 2.3e-09 36.9 0.1 5.1e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETO08116.1 - 4.9e-08 33.2 0.0 2.3e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO08116.1 - 8.2e-08 32.6 0.3 5.3e-07 30.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETO08116.1 - 2.7e-07 30.4 0.0 4.3e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 ETO08116.1 - 1.3e-06 27.8 0.0 2.6e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.2 ETO08116.1 - 6.3e-05 23.5 0.2 0.00015 22.3 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 ETO08116.1 - 0.0019 16.9 0.0 0.0036 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) DUF1869 PF08956.5 ETO08116.1 - 0.041 13.4 0.1 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1869) AdoMet_MTase PF07757.8 ETO08116.1 - 0.07 13.2 0.1 0.38 10.9 0.0 2.1 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase Methyltransf_26 PF13659.1 ETO08116.1 - 0.1 12.6 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Flavodoxin_4 PF12682.2 ETO08117.1 - 0.12 11.7 0.1 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Flavodoxin ASFV_p27 PF06556.6 ETO08118.1 - 0.22 11.4 6.7 0.089 12.6 2.1 2.1 1 1 0 2 2 2 0 IAP-like protein p27 C-terminus DUF365 PF04033.7 ETO08120.1 - 0.2 11.6 3.0 1.2 9.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF365) NACHT PF05729.7 ETO08121.1 - 2.5e-16 59.7 0.0 1.3e-15 57.4 0.0 2.3 1 1 0 1 1 1 1 NACHT domain HEAT_2 PF13646.1 ETO08121.1 - 2.3e-07 30.9 0.0 0.0016 18.6 0.0 3.3 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.17 ETO08121.1 - 2.2e-06 27.2 1.1 0.73 10.0 0.0 6.4 6 0 0 6 6 6 1 HEAT repeat NB-ARC PF00931.17 ETO08121.1 - 3.1e-05 23.0 0.1 3.1e-05 23.0 0.1 2.5 3 0 0 3 3 3 1 NB-ARC domain AAA_16 PF13191.1 ETO08121.1 - 0.0016 18.4 0.0 0.0051 16.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 ETO08121.1 - 0.0083 16.2 0.0 0.031 14.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain DAP3 PF10236.4 ETO08121.1 - 0.0089 14.9 0.0 0.023 13.6 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 ABC_tran PF00005.22 ETO08121.1 - 0.0099 16.1 0.1 0.12 12.6 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_19 PF13245.1 ETO08121.1 - 0.019 14.7 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain MA3 PF02847.12 ETO08121.1 - 0.024 14.3 0.7 0.024 14.3 0.5 3.9 4 0 0 4 4 4 0 MA3 domain AAA_10 PF12846.2 ETO08121.1 - 0.11 11.9 0.0 0.49 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain HEAT_EZ PF13513.1 ETO08121.1 - 0.14 12.7 0.1 34 5.0 0.0 3.8 3 0 0 3 3 3 0 HEAT-like repeat AAA_30 PF13604.1 ETO08121.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 ETO08122.1 - 1.7 8.2 16.9 0.6 9.6 2.7 3.3 3 0 0 3 3 3 0 IncA protein ADIP PF11559.3 ETO08123.1 - 0.027 14.3 5.3 0.043 13.7 3.7 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Bacillus_HBL PF05791.6 ETO08123.1 - 0.04 13.2 5.3 0.05 12.9 3.7 1.1 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) SHR3_chaperone PF08229.6 ETO08123.1 - 0.1 11.5 1.1 0.16 10.9 0.8 1.3 1 0 0 1 1 1 0 ER membrane protein SH3 TPR_1 PF00515.23 ETO08124.1 - 2.7e-07 29.9 0.8 1.6e-06 27.4 0.1 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO08124.1 - 3.7e-06 26.7 0.0 1.1e-05 25.3 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO08124.1 - 0.00023 20.7 0.0 0.00049 19.6 0.0 1.5 1 0 0 1 1 1 1 TPR repeat TPR_7 PF13176.1 ETO08124.1 - 0.00024 20.6 0.0 0.0025 17.4 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO08124.1 - 0.00059 19.5 0.0 0.0016 18.2 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO08124.1 - 0.0012 18.4 0.1 0.0046 16.6 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETO08124.1 - 0.027 14.4 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.1 ETO08124.1 - 0.09 13.0 0.6 1.5 9.2 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat CAP_GLY PF01302.20 ETO08125.1 - 7.5e-13 47.9 0.1 1.3e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain NIF PF03031.13 ETO08126.1 - 1.9e-28 99.1 0.1 4e-28 98.0 0.0 1.5 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase DUF4396 PF14342.1 ETO08127.1 - 5.4e-27 94.5 9.8 1e-26 93.7 6.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) DUF4191 PF13829.1 ETO08127.1 - 0.31 10.1 1.5 5 6.1 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) CCDC84 PF14968.1 ETO08128.1 - 0.26 10.7 5.0 0.58 9.5 3.1 1.7 1 1 1 2 2 2 0 Coiled coil protein 84 WD40 PF00400.27 ETO08129.1 - 1.1e-12 47.2 1.6 1.4e-07 31.0 0.1 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO08129.1 - 0.0014 16.8 0.1 0.0017 16.5 0.1 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 ArdA PF07275.6 ETO08130.1 - 0.0039 17.4 3.2 0.01 16.1 2.2 1.7 1 1 0 1 1 1 1 Antirestriction protein (ArdA) Pkinase PF00069.20 ETO08131.1 - 0.01 15.0 2.0 0.056 12.5 1.4 1.9 1 1 0 1 1 1 0 Protein kinase domain CENP-M PF11111.3 ETO08131.1 - 0.13 11.4 1.5 0.19 10.9 0.8 1.5 1 1 1 2 2 2 0 Centromere protein M (CENP-M) Ion_trans PF00520.26 ETO08132.1 - 0.053 12.7 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 Ion transport protein Paramyxo_NS_C PF02725.9 ETO08132.1 - 0.31 10.6 1.9 0.34 10.5 0.1 1.7 2 0 0 2 2 2 0 Non-structural protein C Takusan PF04822.8 ETO08132.1 - 7.6 6.3 7.3 4.4 7.1 0.2 2.8 2 1 1 3 3 3 0 Takusan FAD_binding_4 PF01565.18 ETO08133.1 - 1.5e-08 34.2 0.0 2.5e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain PH_3 PF14593.1 ETO08133.1 - 0.026 14.4 0.3 0.055 13.3 0.2 1.5 1 0 0 1 1 1 0 PH domain YajC PF02699.10 ETO08133.1 - 0.086 12.5 2.5 0.22 11.2 1.7 1.8 1 1 0 1 1 1 0 Preprotein translocase subunit Copine PF07002.11 ETO08134.1 - 1.6e-18 66.8 0.1 9.2e-12 44.9 0.0 2.4 1 1 1 2 2 2 2 Copine vWA-TerF-like PF10138.4 ETO08134.1 - 0.0081 16.0 0.0 0.026 14.3 0.0 1.7 1 1 1 2 2 2 1 vWA found in TerF C terminus TP53IP5 PF15331.1 ETO08136.1 - 0.31 10.9 4.6 0.49 10.2 3.2 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 SPT16 PF08644.6 ETO08136.1 - 2.9 7.7 6.3 2.2 8.1 3.3 1.6 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) FMO-like PF00743.14 ETO08138.1 - 9.4e-44 149.4 0.4 9.8e-36 123.0 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 ETO08138.1 - 7e-15 55.6 0.0 1e-14 55.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETO08138.1 - 9.7e-09 35.1 0.1 4.3e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 ETO08138.1 - 1.7e-08 34.7 1.7 0.0074 16.6 0.0 3.2 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETO08138.1 - 3.9e-08 33.4 0.0 0.00027 20.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETO08138.1 - 1.5e-07 30.6 0.3 0.0023 16.9 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 ETO08138.1 - 0.00016 21.5 0.2 0.77 9.5 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 ETO08138.1 - 0.00083 18.9 0.1 0.42 10.1 0.0 3.0 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 ETO08138.1 - 0.00098 18.2 0.6 0.0061 15.6 0.1 2.2 3 0 0 3 3 3 1 Thi4 family DAO PF01266.19 ETO08138.1 - 0.0033 16.3 0.2 0.064 12.1 0.0 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETO08138.1 - 0.0045 15.9 0.1 1.9 7.2 0.0 2.9 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.17 ETO08138.1 - 0.0081 15.0 0.1 2.9 6.6 0.0 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.14 ETO08138.1 - 0.019 14.0 0.0 0.063 12.3 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain 2-Hacid_dh_C PF02826.14 ETO08138.1 - 0.024 13.7 0.0 0.23 10.5 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 ETO08138.1 - 0.14 10.5 0.1 0.42 9.0 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Cyc-maltodext_N PF09087.6 ETO08139.1 - 0.048 13.5 0.3 0.094 12.6 0.2 1.4 1 0 0 1 1 1 0 Cyclomaltodextrinase, N-terminal Iron_permease PF04120.7 ETO08140.1 - 0.83 9.2 0.0 0.83 9.2 0.0 2.2 3 0 0 3 3 3 0 Low affinity iron permease RGS PF00615.14 ETO08141.1 - 2.6e-06 27.5 10.3 0.00019 21.5 7.1 2.2 1 1 0 1 1 1 1 Regulator of G protein signaling domain EntA_Immun PF08951.5 ETO08141.1 - 0.051 13.7 2.3 0.083 13.0 0.7 1.9 2 0 0 2 2 2 0 Enterocin A Immunity Toxin_46 PF15526.1 ETO08141.1 - 0.3 11.2 1.9 1 9.5 1.3 1.9 1 0 0 1 1 1 0 Putative toxin 46 DUF1501 PF07394.7 ETO08142.1 - 5.6 5.6 9.9 0.57 8.9 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1501) Kinesin PF00225.18 ETO08143.1 - 0.00068 18.4 1.7 0.00081 18.1 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain DUF641 PF04859.7 ETO08143.1 - 0.0028 17.4 3.6 0.0028 17.4 2.5 2.5 2 1 0 2 2 2 1 Plant protein of unknown function (DUF641) FadA PF09403.5 ETO08143.1 - 0.014 15.4 1.0 0.014 15.4 0.7 2.4 2 0 0 2 2 2 0 Adhesion protein FadA Phage_GP20 PF06810.6 ETO08143.1 - 1.5 8.2 13.0 0.84 9.0 2.6 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 Spore_III_AF PF09581.5 ETO08143.1 - 1.6 8.5 8.0 0.095 12.5 1.2 1.9 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) FTA4 PF13093.1 ETO08143.1 - 1.9 7.8 10.5 0.18 11.1 2.1 2.0 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF2175 PF09943.4 ETO08143.1 - 2.2 8.4 6.8 15 5.7 0.9 2.7 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) DUF342 PF03961.8 ETO08143.1 - 4.5 5.5 10.6 1.1 7.6 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF342) AAA_27 PF13514.1 ETO08143.1 - 5.4 4.5 11.0 0.54 7.8 1.6 2.0 2 0 0 2 2 2 0 AAA domain Macoilin PF09726.4 ETO08143.1 - 6.5 4.9 11.6 0.06 11.6 1.1 2.1 2 0 0 2 2 2 0 Transmembrane protein Sas10 PF09368.5 ETO08144.1 - 0.0012 18.9 0.2 0.0028 17.7 0.2 1.6 1 0 0 1 1 1 1 Sas10 C-terminal domain DUF3492 PF11997.3 ETO08144.1 - 0.073 12.5 4.3 0.09 12.3 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) LMBR1 PF04791.11 ETO08144.1 - 0.88 8.0 5.2 1.1 7.7 3.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Neur_chan_memb PF02932.11 ETO08144.1 - 1.1 9.1 8.7 1.3 8.8 6.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ndc1_Nup PF09531.5 ETO08144.1 - 3.8 5.8 10.2 4.3 5.6 7.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CDC45 PF02724.9 ETO08144.1 - 5.4 4.9 19.0 6.1 4.7 13.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3595 PF12166.3 ETO08145.1 - 0.12 11.1 4.4 0.16 10.7 3.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) Med15 PF09606.5 ETO08145.1 - 2.9 5.9 47.7 3.4 5.7 33.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal ECM1 PF05782.6 ETO08145.1 - 3.6 6.1 17.0 4.4 5.9 11.8 1.1 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) FYVE PF01363.16 ETO08147.1 - 2.6e-16 59.2 9.9 2.6e-16 59.2 6.8 2.0 2 1 0 2 2 2 1 FYVE zinc finger MIP-T3 PF10243.4 ETO08147.1 - 0.0061 15.1 9.5 0.0061 15.1 6.6 2.2 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 HARP PF07443.8 ETO08148.1 - 0.029 13.7 0.3 0.067 12.5 0.2 1.6 1 0 0 1 1 1 0 HepA-related protein (HARP) YxiJ PF14176.1 ETO08148.1 - 0.053 13.6 8.6 0.42 10.7 1.1 2.4 2 1 0 2 2 2 0 YxiJ-like protein WD40 PF00400.27 ETO08149.1 - 3.8e-92 299.1 30.0 2.2e-15 55.8 0.1 8.6 8 1 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO08149.1 - 1.4e-15 57.5 0.0 5.1e-08 32.8 0.1 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 ETO08149.1 - 1.6e-11 44.1 3.2 0.00039 19.9 0.2 3.3 1 1 2 3 3 3 3 PQQ-like domain Cytochrom_D1 PF02239.11 ETO08149.1 - 3e-08 32.3 1.0 0.012 13.8 0.2 3.2 1 1 3 4 4 4 4 Cytochrome D1 heme domain PD40 PF07676.7 ETO08149.1 - 8.2e-08 31.7 9.3 13 5.6 0.0 6.5 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 ETO08149.1 - 2.2e-06 26.9 5.5 0.19 10.7 0.1 4.6 1 1 4 5 5 5 3 Neuroblastoma-amplified sequence, N terminal DUF1258 PF06869.7 ETO08149.1 - 2.3e-06 26.8 1.4 0.19 10.7 0.0 5.1 1 1 4 5 5 5 1 Protein of unknown function (DUF1258) Proteasome_A_N PF10584.4 ETO08149.1 - 3.7e-06 26.1 10.0 23 4.4 0.0 8.7 12 0 0 12 12 12 0 Proteasome subunit A N-terminal signature WXG100 PF06013.7 ETO08149.1 - 1.3e-05 25.0 0.0 47 4.0 0.0 6.2 7 0 0 7 7 7 0 Proteins of 100 residues with WXG Gmad1 PF10647.4 ETO08149.1 - 1.7e-05 24.3 0.3 0.05 12.9 0.0 3.9 3 1 0 3 3 3 1 Lipoprotein LpqB beta-propeller domain DUF3312 PF11768.3 ETO08149.1 - 0.00054 18.3 0.0 7.6 4.6 0.0 4.5 4 1 0 5 5 5 1 Protein of unknown function (DUF3312) PQQ_3 PF13570.1 ETO08149.1 - 0.00086 19.4 2.4 26 5.2 0.0 5.2 3 1 0 3 3 3 0 PQQ-like domain DPPIV_N PF00930.16 ETO08149.1 - 0.00098 17.8 0.5 3.5 6.1 0.0 4.8 1 1 5 6 6 6 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region NYD-SP28_assoc PF14775.1 ETO08149.1 - 0.0083 15.8 0.1 1.3e+02 2.3 0.0 5.5 7 0 0 7 7 7 0 Sperm tail C-terminal domain SLH PF00395.15 ETO08149.1 - 0.011 15.4 0.1 40 4.0 0.0 5.0 4 1 1 5 5 5 0 S-layer homology domain PQQ PF01011.16 ETO08149.1 - 0.015 14.8 1.4 64 3.3 0.0 5.2 6 1 1 7 7 6 0 PQQ enzyme repeat DUF3732 PF12532.3 ETO08149.1 - 0.049 13.1 2.7 42 3.5 0.0 4.4 1 1 3 5 5 5 0 Protein of unknown function (DUF3732) Peptidase_C9 PF01707.11 ETO08149.1 - 0.06 12.9 0.0 14 5.2 0.0 3.8 6 0 0 6 6 6 0 Peptidase family C9 dsrm PF00035.20 ETO08149.1 - 0.12 12.9 0.2 69 4.1 0.0 4.2 6 0 0 6 6 5 0 Double-stranded RNA binding motif rve PF00665.21 ETO08150.1 - 5.1e-10 39.5 0.0 8.6e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain TMEM151 PF14857.1 ETO08151.1 - 0.089 11.3 4.5 0.13 10.8 3.1 1.2 1 0 0 1 1 1 0 TMEM151 family PUF PF00806.14 ETO08152.1 - 2.8e-23 80.0 7.7 1.1e-05 24.6 0.0 7.3 8 0 0 8 8 8 5 Pumilio-family RNA binding repeat DUF1325 PF07039.6 ETO08152.1 - 0.065 12.8 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 SGF29 tudor-like domain Clathrin PF00637.15 ETO08152.1 - 0.069 12.7 1.1 0.78 9.3 0.2 2.5 2 0 0 2 2 2 0 Region in Clathrin and VPS ACP_syn_III_C PF08541.5 ETO08152.1 - 0.13 12.2 0.0 8.6 6.4 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal IL17 PF06083.6 ETO08153.1 - 0.0045 17.0 0.8 0.0071 16.3 0.6 1.3 1 0 0 1 1 1 1 Interleukin-17 TRAP-gamma PF07074.7 ETO08153.1 - 0.67 9.4 7.5 0.81 9.2 5.0 1.3 1 1 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) WD40 PF00400.27 ETO08155.1 - 6.1e-52 171.7 26.4 2.3e-10 39.9 0.6 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO08155.1 - 5.1e-09 34.8 7.3 0.00047 18.4 0.2 4.2 1 1 0 4 4 4 3 Nucleoporin Nup120/160 WD40 PF00400.27 ETO08157.1 - 1.2e-93 303.9 15.7 2.6e-14 52.4 0.3 7.0 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO08157.1 - 1.9e-12 47.2 0.0 0.00092 18.9 0.0 3.8 1 1 2 4 4 4 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO08157.1 - 2.6e-10 39.0 10.5 0.039 12.0 0.0 5.9 1 1 4 6 6 6 4 Nucleoporin Nup120/160 PD40 PF07676.7 ETO08157.1 - 6.1e-10 38.5 7.5 0.87 9.3 0.1 7.1 7 0 0 7 7 7 3 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO08157.1 - 1.7e-07 30.3 5.3 0.49 9.0 0.1 4.6 1 1 4 5 5 5 3 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO08157.1 - 5.1e-07 28.3 0.4 0.0004 18.7 0.1 2.7 1 1 1 3 3 3 3 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO08157.1 - 1.2e-05 24.5 3.9 5.1 6.1 0.0 5.7 1 1 6 7 7 7 2 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 ETO08157.1 - 0.00026 20.2 14.1 2.5 7.5 0.0 6.8 7 0 0 7 7 7 1 Proteasome subunit A N-terminal signature DPPIV_N PF00930.16 ETO08157.1 - 0.0014 17.3 0.0 2.3 6.7 0.0 4.2 1 1 4 5 5 5 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Resistin PF06954.6 ETO08157.1 - 0.0073 16.5 0.1 7.4 6.9 0.0 4.1 2 2 3 5 5 5 1 Resistin Gmad1 PF10647.4 ETO08157.1 - 0.012 14.9 0.5 0.13 11.6 0.1 2.2 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain Coatomer_WDAD PF04053.9 ETO08157.1 - 0.019 13.8 0.1 6.6 5.4 0.0 2.4 1 1 2 3 3 3 0 Coatomer WD associated region MMS1_N PF10433.4 ETO08157.1 - 0.04 12.0 0.1 10 4.1 0.0 3.3 1 1 3 4 4 4 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF3312 PF11768.3 ETO08157.1 - 0.043 12.0 0.0 0.35 9.0 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3312) Colicin_Ia PF11504.3 ETO08157.1 - 0.085 12.7 0.5 25 4.8 0.0 4.6 5 1 1 6 6 6 0 Colicin Ia Kelch_1 PF01344.20 ETO08158.1 - 2e-06 27.2 2.9 5e-06 25.9 1.3 2.1 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.1 ETO08158.1 - 5e-05 22.9 1.7 0.013 15.2 0.2 2.8 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO08158.1 - 5.7e-05 23.1 0.9 0.00011 22.2 0.1 1.9 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO08158.1 - 0.0005 19.7 4.7 0.0057 16.3 0.3 3.9 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 ETO08158.1 - 0.00071 19.6 4.1 0.0096 16.0 0.5 2.9 2 1 1 3 3 3 1 Kelch motif Kelch_5 PF13854.1 ETO08158.1 - 0.02 14.8 0.5 0.33 10.9 0.4 2.5 2 0 0 2 2 2 0 Kelch motif Synaptobrevin PF00957.16 ETO08159.1 - 0.019 14.5 2.3 0.033 13.7 1.4 1.6 1 1 0 1 1 1 0 Synaptobrevin zf-RING_2 PF13639.1 ETO08159.1 - 0.033 14.0 0.1 0.097 12.5 0.1 1.9 1 0 0 1 1 1 0 Ring finger domain DUF1664 PF07889.7 ETO08159.1 - 0.038 13.7 2.6 0.054 13.2 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2808 PF10989.3 ETO08159.1 - 0.044 13.3 0.7 0.16 11.6 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2808) DUF2607 PF10795.4 ETO08159.1 - 0.052 13.3 2.2 4.8 7.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2607) zf-GRF PF06839.7 ETO08159.1 - 0.065 13.1 0.3 0.2 11.5 0.2 1.8 1 0 0 1 1 1 0 GRF zinc finger HalX PF08663.5 ETO08159.1 - 0.49 10.4 4.5 10 6.1 0.1 2.6 1 1 2 3 3 3 0 HalX domain V_ATPase_I PF01496.14 ETO08159.1 - 1.9 6.2 10.7 2.2 6.0 7.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DASH_Hsk3 PF08227.6 ETO08159.1 - 2.5 8.3 7.3 0.29 11.3 1.1 2.5 3 1 0 3 3 3 0 DASH complex subunit Hsk3 like DUF4271 PF14093.1 ETO08160.1 - 0.0034 17.0 7.5 0.0053 16.4 5.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4271) Tenui_NCP PF04876.7 ETO08160.1 - 0.0044 16.5 0.5 0.0065 16.0 0.4 1.3 1 0 0 1 1 1 1 Tenuivirus major non-capsid protein Rabaptin PF03528.10 ETO08160.1 - 0.037 13.9 1.0 0.073 12.9 0.7 1.5 1 0 0 1 1 1 0 Rabaptin WD40 PF00400.27 ETO08161.1 - 2.6e-84 274.3 18.2 4e-11 42.3 0.2 8.5 8 0 0 8 8 8 8 WD domain, G-beta repeat NACHT PF05729.7 ETO08161.1 - 3e-10 39.9 0.0 9.1e-10 38.4 0.0 1.9 1 0 0 1 1 1 1 NACHT domain Pentapeptide PF00805.17 ETO08161.1 - 1.3e-06 27.4 3.3 2.9e-06 26.3 2.3 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO08161.1 - 5.7e-06 26.0 0.3 1.6e-05 24.6 0.2 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Cytochrom_D1 PF02239.11 ETO08161.1 - 2.8e-05 22.5 3.6 0.18 10.0 0.1 3.2 2 1 1 3 3 3 2 Cytochrome D1 heme domain Pentapeptide_3 PF13576.1 ETO08161.1 - 7e-05 22.6 0.4 0.00018 21.3 0.3 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA_22 PF13401.1 ETO08161.1 - 0.00013 22.1 0.0 0.00066 19.8 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETO08161.1 - 0.00075 19.8 0.0 0.00075 19.8 0.0 3.8 4 1 0 4 4 4 1 AAA domain AAA_17 PF13207.1 ETO08161.1 - 0.0012 19.6 0.0 0.011 16.6 0.0 2.8 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 ETO08161.1 - 0.0019 17.3 2.5 0.014 14.4 0.0 3.3 4 0 0 4 4 4 1 KaiC ABC_tran PF00005.22 ETO08161.1 - 0.021 15.1 0.7 0.1 12.9 0.0 2.5 3 0 0 3 3 3 0 ABC transporter AAA_16 PF13191.1 ETO08161.1 - 0.032 14.2 0.1 0.38 10.7 0.0 2.5 1 1 1 2 2 2 0 AAA ATPase domain WD40 PF00400.27 ETO08162.1 - 4.1e-25 86.6 4.1 1.4e-12 46.9 0.1 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO08162.1 - 0.015 13.4 0.1 0.028 12.5 0.0 1.5 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Nbas_N PF15492.1 ETO08162.1 - 0.039 13.0 0.2 2.7 7.0 0.0 2.3 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal USP7_C2 PF14533.1 ETO08162.1 - 0.055 12.8 0.1 0.44 9.9 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-specific protease C-terminal PD40 PF07676.7 ETO08162.1 - 0.86 9.3 3.4 4.8 6.9 0.0 2.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF4293 PF14126.1 ETO08163.1 - 0.017 15.0 3.9 0.035 14.0 2.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) DUF1512 PF07431.7 ETO08163.1 - 0.058 12.1 0.0 0.25 10.0 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1512) VanZ PF04892.7 ETO08163.1 - 0.1 12.5 3.5 0.2 11.6 2.4 1.8 1 1 0 1 1 1 0 VanZ like family PUB PF09409.5 ETO08165.1 - 0.029 14.1 4.5 0.03 14.0 0.3 2.9 2 1 1 3 3 3 0 PUB domain CUE PF02845.11 ETO08165.1 - 0.13 11.7 0.5 0.61 9.6 0.1 2.2 2 0 0 2 2 2 0 CUE domain WD40 PF00400.27 ETO08166.1 - 1.1e-15 56.8 3.0 2.4e-09 36.7 0.3 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat eIF2A PF08662.6 ETO08166.1 - 0.001 18.7 3.1 0.037 13.7 0.6 2.1 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO08166.1 - 0.0037 15.4 0.3 0.0062 14.7 0.2 1.5 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Thermopsin PF05317.6 ETO08166.1 - 0.015 14.2 2.9 0.015 14.1 0.8 1.7 2 0 0 2 2 2 0 Thermopsin DUF1801 PF08818.6 ETO08166.1 - 0.13 12.3 0.5 0.26 11.4 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DU1801) WD40 PF00400.27 ETO08168.1 - 6.3e-31 105.1 14.2 9.3e-14 50.6 0.1 5.4 6 1 1 7 7 7 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO08168.1 - 5e-06 25.0 0.6 0.0095 14.2 0.0 2.6 1 1 2 3 3 3 2 Cytochrome D1 heme domain eIF2A PF08662.6 ETO08168.1 - 0.00064 19.4 0.1 0.26 10.9 0.0 2.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO08168.1 - 0.0046 15.1 1.1 0.079 11.0 0.1 2.6 1 1 0 2 2 2 1 Nucleoporin Nup120/160 PD40 PF07676.7 ETO08168.1 - 0.021 14.4 4.2 3.3 7.4 0.0 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Sel1 PF08238.7 ETO08169.1 - 6.2e-06 26.6 1.2 0.00039 20.9 0.8 3.3 3 0 0 3 3 3 1 Sel1 repeat zf-MIZ PF02891.15 ETO08170.1 - 4.3 6.9 7.8 3.7 7.1 1.2 2.9 3 1 0 3 3 3 0 MIZ/SP-RING zinc finger Kelch_6 PF13964.1 ETO08172.1 - 1.8e-07 30.9 1.3 0.033 14.3 0.1 4.4 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO08172.1 - 4.7e-05 22.8 2.0 0.00086 18.7 0.2 3.2 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO08172.1 - 7.1e-05 22.4 1.2 0.52 10.1 0.1 4.1 3 0 0 3 3 3 2 Kelch motif PH PF00169.24 ETO08173.1 - 0.00017 21.7 0.2 0.00067 19.8 0.2 2.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 ETO08173.1 - 0.059 13.6 4.9 0.055 13.7 0.4 3.1 2 1 0 2 2 2 0 Pleckstrin homology domain SelP_N PF04592.9 ETO08174.1 - 1.3 8.3 13.7 2 7.7 9.5 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Glyco_hydro_38C PF07748.8 ETO08175.1 - 1.9e-23 83.0 0.1 2.6e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Peptidase_M44 PF03410.8 ETO08177.1 - 0.0041 15.4 0.0 0.0041 15.4 0.0 1.1 1 0 0 1 1 1 1 Protein G1 PUB PF09409.5 ETO08177.1 - 0.0042 16.7 3.9 0.019 14.7 0.2 2.8 1 1 0 2 2 2 1 PUB domain Pyr_redox_3 PF13738.1 ETO08178.1 - 2.3e-05 24.5 0.0 3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETO08178.1 - 0.00047 18.4 0.0 0.00047 18.4 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Shikimate_DH PF01488.15 ETO08178.1 - 0.00077 19.5 0.0 0.001 19.2 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 ETO08178.1 - 0.0012 19.1 0.0 0.0024 18.2 0.0 1.6 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Oxidored_nitro PF00148.14 ETO08178.1 - 0.016 13.9 0.0 0.018 13.7 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase K_oxygenase PF13434.1 ETO08178.1 - 0.027 13.4 0.0 0.032 13.1 0.0 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.14 ETO08178.1 - 0.092 11.8 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPR_MLP1_2 PF07926.7 ETO08179.1 - 0.017 14.9 14.1 0.017 14.9 9.8 3.3 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Symplekin_C PF12295.3 ETO08180.1 - 2.1e-34 119.0 0.2 2.1e-34 119.0 0.1 1.5 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal Phyto_Pns9_10 PF05878.6 ETO08180.1 - 0.0072 15.3 0.1 0.0072 15.3 0.0 1.1 1 0 0 1 1 1 1 Phytoreovirus nonstructural protein Pns9/Pns10 TLP-20 PF06088.6 ETO08180.1 - 0.12 12.0 2.6 0.19 11.3 1.8 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Podoplanin PF05808.6 ETO08180.1 - 0.35 10.3 3.7 0.59 9.6 2.6 1.3 1 0 0 1 1 1 0 Podoplanin SNAPc19 PF15497.1 ETO08180.1 - 1.4 9.1 6.1 3.2 8.0 4.2 1.6 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 RabGAP-TBC PF00566.13 ETO08181.1 - 7e-16 58.3 2.2 1e-15 57.8 1.5 1.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain BSMAP PF12280.3 ETO08181.1 - 0.062 13.1 1.2 0.094 12.5 0.8 1.3 1 0 0 1 1 1 0 Brain specific membrane anchored protein Ribosomal_60s PF00428.14 ETO08181.1 - 0.51 10.7 7.7 0.81 10.1 5.3 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Rota_VP2 PF05087.7 ETO08181.1 - 0.61 7.9 6.1 0.76 7.6 4.3 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein Med12-LCEWAV PF12145.3 ETO08181.1 - 0.93 7.9 5.2 1.2 7.5 3.6 1.1 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain Glyco_hydro_3_C PF01915.17 ETO08183.1 - 1.2e-13 51.1 0.0 1.4e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain TMCO5 PF14992.1 ETO08184.1 - 0.031 13.4 1.6 0.059 12.4 1.1 1.4 1 0 0 1 1 1 0 TMCO5 family DUF2899 PF11449.3 ETO08184.1 - 0.11 11.6 3.9 0.078 12.1 1.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2899) 7TM_GPCR_Srh PF10318.4 ETO08184.1 - 0.37 9.5 10.8 0.68 8.6 7.5 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh Mak10 PF04112.8 ETO08184.1 - 4.1 6.6 6.9 0.33 10.1 0.4 2.2 3 0 0 3 3 3 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase DUF914 PF06027.7 ETO08185.1 - 3.6e-21 75.3 1.5 4.5e-21 75.0 1.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 ETO08185.1 - 0.015 15.3 6.9 0.021 14.8 4.8 1.2 1 0 0 1 1 1 0 EamA-like transporter family DivIC PF04977.10 ETO08185.1 - 0.073 12.5 0.2 0.17 11.3 0.1 1.6 1 0 0 1 1 1 0 Septum formation initiator RhoGEF PF00621.15 ETO08186.1 - 2.3e-18 66.6 0.2 3e-18 66.3 0.1 1.2 1 0 0 1 1 1 1 RhoGEF domain NOA36 PF06524.7 ETO08187.1 - 0.014 14.6 1.4 0.017 14.3 1.0 1.0 1 0 0 1 1 1 0 NOA36 protein Tim54 PF11711.3 ETO08187.1 - 0.55 8.7 8.5 0.59 8.6 5.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CytadhesinP1 PF12378.3 ETO08187.1 - 3.7 7.5 8.9 12 5.8 5.0 2.0 1 1 1 2 2 2 0 Trypsin-sensitive surface-exposed protein TIMELESS PF04821.9 ETO08187.1 - 5.2 6.2 8.8 2.4 7.3 4.5 1.5 1 1 1 2 2 2 0 Timeless protein DUF3987 PF13148.1 ETO08187.1 - 6.1 5.2 7.1 6.1 5.2 4.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Sec62 PF03839.11 ETO08187.1 - 6.5 6.1 10.4 7 5.9 7.2 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 Peptidase_S49_N PF08496.5 ETO08187.1 - 7 6.4 8.2 8.2 6.1 5.7 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1662 PF07878.6 ETO08188.1 - 0.068 12.9 0.1 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1662) Arm PF00514.18 ETO08188.1 - 0.11 12.4 0.0 8.6 6.3 0.0 3.0 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Ribosomal_S19 PF00203.16 ETO08189.1 - 2.9e-21 74.8 0.2 3.7e-21 74.5 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 CENP-T PF15511.1 ETO08190.1 - 0.012 14.9 48.3 0.1 11.8 10.8 2.3 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 ETO08190.1 - 0.023 12.6 92.4 0.087 10.7 25.3 2.4 2 0 0 2 2 2 0 Nop14-like family SH3_1 PF00018.23 ETO08192.1 - 2e-30 103.9 4.5 1.1e-14 53.5 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 ETO08192.1 - 1.1e-23 82.5 3.1 3.9e-11 42.3 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 ETO08192.1 - 1.9e-23 81.6 0.4 1.4e-12 46.8 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain VHP PF02209.14 ETO08192.1 - 1.8e-14 53.0 0.7 4.3e-14 51.9 0.5 1.7 1 0 0 1 1 1 1 Villin headpiece domain FYVE PF01363.16 ETO08192.1 - 1.7e-07 31.0 12.7 1.8e-05 24.5 8.9 2.4 1 1 0 1 1 1 1 FYVE zinc finger Sec20 PF03908.8 ETO08192.1 - 0.27 10.9 1.1 0.72 9.6 0.8 1.7 1 0 0 1 1 1 0 Sec20 PH PF00169.24 ETO08193.1 - 1.9e-07 31.1 0.8 3.2e-07 30.4 0.5 1.4 1 0 0 1 1 1 1 PH domain L6_membrane PF05805.7 ETO08193.1 - 0.054 13.0 0.0 0.077 12.5 0.0 1.2 1 0 0 1 1 1 0 L6 membrane protein RhoGEF PF00621.15 ETO08194.1 - 8.1e-18 64.9 1.8 1.1e-17 64.5 1.2 1.2 1 0 0 1 1 1 1 RhoGEF domain PXA PF02194.10 ETO08194.1 - 0.025 14.1 1.9 0.53 9.8 0.0 2.0 1 1 1 2 2 2 0 PXA domain DUF788 PF05620.6 ETO08195.1 - 0.017 15.0 2.2 0.017 15.0 1.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF788) ResB PF05140.9 ETO08195.1 - 0.04 12.4 0.0 1.8 7.0 0.0 2.3 2 0 0 2 2 2 0 ResB-like family DUF3643 PF12356.3 ETO08195.1 - 0.091 12.0 0.8 0.19 11.0 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3643) DUF897 PF05982.7 ETO08196.1 - 0.0068 15.2 0.1 0.019 13.7 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF897) TIP_N PF12457.3 ETO08197.1 - 0.041 13.9 0.8 0.041 13.9 0.6 2.6 2 1 1 3 3 3 0 Tuftelin interacting protein N terminal DUF572 PF04502.8 ETO08197.1 - 0.16 11.1 10.0 0.19 10.8 6.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF1675 PF07897.6 ETO08197.1 - 2.7 7.7 9.4 3.6 7.3 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Peptidase_S64 PF08192.6 ETO08197.1 - 4.6 5.4 10.3 5.4 5.2 7.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 RNase_H PF00075.19 ETO08198.1 - 8.3e-07 29.4 0.0 9.6e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 RNase H CAS_CSE1 PF03378.10 ETO08199.1 - 4.3e-23 81.3 1.6 5.7e-13 47.9 0.0 2.1 1 1 1 2 2 2 2 CAS/CSE protein, C-terminus CAS_CSE1 PF03378.10 ETO08200.1 - 1.4e-50 171.8 5.5 1.4e-50 171.8 3.8 2.0 2 0 0 2 2 2 2 CAS/CSE protein, C-terminus Cse1 PF08506.5 ETO08200.1 - 7.1e-47 159.7 0.4 7.1e-47 159.7 0.3 1.9 2 1 1 3 3 3 1 Cse1 WD40 PF00400.27 ETO08201.1 - 2.5e-80 261.7 16.7 7.8e-13 47.7 0.3 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO08201.1 - 3.2e-12 46.5 0.1 0.00017 21.4 0.0 3.5 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO08201.1 - 2.9e-07 29.1 0.5 0.0046 15.2 0.0 2.3 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.3 ETO08201.1 - 6.9e-05 21.1 7.8 0.31 9.1 0.1 4.8 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Resistin PF06954.6 ETO08201.1 - 0.00049 20.3 0.0 9.6 6.5 0.0 4.7 2 2 3 5 5 5 1 Resistin Gmad1 PF10647.4 ETO08201.1 - 0.0005 19.5 0.2 0.0022 17.4 0.1 2.0 2 1 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain Nucleoporin_N PF08801.6 ETO08201.1 - 0.0031 16.3 5.4 1.9 7.1 0.2 4.0 1 1 2 3 3 3 2 Nup133 N terminal like DUF1258 PF06869.7 ETO08201.1 - 0.0091 15.1 1.4 3.5 6.6 0.1 3.5 1 1 2 4 4 4 1 Protein of unknown function (DUF1258) PD40 PF07676.7 ETO08201.1 - 0.01 15.4 6.5 9 6.0 0.1 5.1 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF4221 PF13970.1 ETO08201.1 - 0.023 14.0 0.1 7.4 5.7 0.0 2.7 1 1 1 3 3 3 0 Domain of unknown function (DUF4221) Hira PF07569.6 ETO08201.1 - 0.035 13.3 0.6 1.3 8.2 0.0 3.3 2 1 3 5 5 5 0 TUP1-like enhancer of split Str_synth PF03088.11 ETO08201.1 - 0.12 12.4 0.4 37 4.4 0.0 4.2 4 2 2 6 6 6 0 Strictosidine synthase WD40 PF00400.27 ETO08202.1 - 6.2e-81 263.6 18.3 1.1e-11 44.1 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO08202.1 - 2.3e-08 32.6 12.3 0.05 11.7 0.1 5.4 2 2 3 5 5 5 3 Nucleoporin Nup120/160 DUF1258 PF06869.7 ETO08202.1 - 1.3e-05 24.4 1.5 0.069 12.2 0.0 3.9 2 2 2 4 4 4 2 Protein of unknown function (DUF1258) Cytochrom_D1 PF02239.11 ETO08202.1 - 3e-05 22.4 4.5 0.17 10.1 0.1 3.3 2 1 2 4 4 4 3 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO08202.1 - 8.3e-05 22.1 3.1 0.00071 19.0 0.8 2.7 1 1 0 2 2 2 1 PQQ-like domain Mid2 PF04478.7 ETO08202.1 - 0.00049 19.5 4.5 6.8 6.0 0.1 4.4 2 2 2 4 4 4 1 Mid2 like cell wall stress sensor Nucleoporin_N PF08801.6 ETO08202.1 - 0.0014 17.4 11.3 0.57 8.8 1.4 4.4 1 1 1 2 2 2 2 Nup133 N terminal like DUF2415 PF10313.4 ETO08202.1 - 0.014 15.1 0.1 2 8.1 0.1 2.9 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) Proteasome_A_N PF10584.4 ETO08202.1 - 0.026 13.8 5.4 6.7 6.1 0.0 4.8 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature PLD_C PF12357.3 ETO08202.1 - 0.054 13.0 0.5 79 2.8 0.0 4.4 4 1 0 5 5 5 0 Phospholipase D C terminal PD40 PF07676.7 ETO08202.1 - 0.33 10.6 14.4 39 4.0 0.1 6.4 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat TRAM_LAG1_CLN8 PF03798.11 ETO08204.1 - 4.4e-22 78.6 25.1 4.4e-22 78.6 17.4 1.4 2 0 0 2 2 2 1 TLC domain DUF3416 PF11896.3 ETO08205.1 - 0.12 12.3 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3416) WD40 PF00400.27 ETO08206.1 - 2.2e-106 344.3 30.1 1.8e-11 43.4 0.2 10.7 10 0 0 10 10 10 10 WD domain, G-beta repeat NACHT PF05729.7 ETO08206.1 - 2.3e-07 30.6 0.0 5.3e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETO08206.1 - 1.5e-06 28.3 0.1 6.5e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain Pentapeptide PF00805.17 ETO08206.1 - 5.4e-06 25.5 4.9 1.2e-05 24.3 2.7 2.1 1 1 0 1 1 1 1 Pentapeptide repeats (8 copies) AAA_18 PF13238.1 ETO08206.1 - 1.7e-05 25.1 0.1 1.7e-05 25.1 0.0 2.8 2 1 1 3 3 3 1 AAA domain Pentapeptide_4 PF13599.1 ETO08206.1 - 0.001 18.8 0.1 0.003 17.3 0.0 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) PD40 PF07676.7 ETO08206.1 - 0.0027 17.3 3.0 9.1 6.0 0.0 5.7 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat AAA_17 PF13207.1 ETO08206.1 - 0.0061 17.3 0.0 0.041 14.6 0.0 2.6 1 0 0 1 1 1 1 AAA domain Pentapeptide_3 PF13576.1 ETO08206.1 - 0.0068 16.2 0.7 0.027 14.3 0.5 2.0 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA PF00004.24 ETO08206.1 - 0.047 13.8 0.1 0.25 11.5 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETO08206.1 - 0.084 12.8 0.0 0.45 10.4 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain WD40 PF00400.27 ETO08207.1 - 1.2e-28 97.8 3.2 1.1e-12 47.2 0.0 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO08207.1 - 3e-05 22.3 1.2 0.1 10.7 0.1 2.9 1 1 2 3 3 3 3 Nucleoporin Nup120/160 PD40 PF07676.7 ETO08207.1 - 0.0018 17.9 0.2 1.7 8.4 0.0 2.3 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 ETO08207.1 - 0.0037 16.3 0.1 0.35 9.9 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1258) Cytochrom_D1 PF02239.11 ETO08207.1 - 0.027 12.7 0.1 0.035 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytochrome D1 heme domain DPPIV_N PF00930.16 ETO08207.1 - 0.034 12.7 0.0 0.86 8.1 0.0 2.0 1 1 1 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Coatomer_WDAD PF04053.9 ETO08207.1 - 0.068 11.9 0.0 0.18 10.5 0.0 1.5 1 1 1 2 2 2 0 Coatomer WD associated region Proteasome_A_N PF10584.4 ETO08207.1 - 0.6 9.4 2.8 8.5 5.8 0.2 2.5 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature Clathrin_lg_ch PF01086.12 ETO08208.1 - 3.6e-10 40.1 22.6 5.9e-10 39.4 15.4 1.4 1 1 0 1 1 1 1 Clathrin light chain UvrD-helicase PF00580.16 ETO08208.1 - 0.22 10.7 13.0 0.24 10.6 9.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Ripply PF14998.1 ETO08208.1 - 0.58 10.2 10.2 0.5 10.5 2.0 2.7 2 1 1 3 3 3 0 Transcription Regulator Membralin PF09746.4 ETO08208.1 - 2.3 7.1 6.0 2.8 6.9 4.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein IncA PF04156.9 ETO08208.1 - 3.3 7.2 10.0 4.6 6.7 6.9 1.4 1 0 0 1 1 1 0 IncA protein Asp-B-Hydro_N PF05279.6 ETO08208.1 - 4.5 7.0 15.4 8.6 6.1 5.3 2.1 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region DNA_primase_S PF01896.14 ETO08208.1 - 5.5 6.7 8.3 19 5.0 5.7 1.9 1 1 0 1 1 1 0 Eukaryotic and archaeal DNA primase small subunit VDE PF07137.6 ETO08209.1 - 0.06 13.1 0.2 0.22 11.3 0.3 1.8 2 0 0 2 2 2 0 Violaxanthin de-epoxidase (VDE) SMN PF06003.7 ETO08209.1 - 0.19 10.7 2.2 0.29 10.2 1.5 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Zip PF02535.17 ETO08210.1 - 0.22 10.4 4.7 0.059 12.3 0.2 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter RGS PF00615.14 ETO08211.1 - 0.022 14.8 0.9 0.022 14.8 0.6 1.8 2 0 0 2 2 2 0 Regulator of G protein signaling domain Striatin PF08232.7 ETO08211.1 - 0.13 12.6 10.8 0.21 11.8 7.5 1.3 1 0 0 1 1 1 0 Striatin family NOA36 PF06524.7 ETO08211.1 - 1.1 8.4 11.7 1.9 7.6 8.1 1.3 1 0 0 1 1 1 0 NOA36 protein Ndc1_Nup PF09531.5 ETO08211.1 - 1.5 7.1 9.6 1.8 6.8 5.8 1.6 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup POX PF07526.6 ETO08211.1 - 1.6 8.9 13.2 0.098 12.8 3.6 2.1 1 1 0 2 2 2 0 Associated with HOX DUF3595 PF12166.3 ETO08211.1 - 2.6 6.7 11.6 3.3 6.4 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) PT PF04886.7 ETO08212.1 - 8.8e-05 21.7 15.0 8.8e-05 21.7 10.4 2.1 2 0 0 2 2 2 1 PT repeat Kelch_6 PF13964.1 ETO08212.1 - 0.081 13.1 5.9 6.7 7.0 0.0 3.8 4 0 0 4 4 4 0 Kelch motif Kelch_1 PF01344.20 ETO08212.1 - 0.22 11.1 2.6 4.4 6.9 0.0 3.0 3 0 0 3 3 3 0 Kelch motif MGC-24 PF05283.6 ETO08212.1 - 8.1 6.1 9.2 1.4 8.7 3.7 1.6 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) Herpes_LMP2 PF07415.6 ETO08213.1 - 0.0003 19.5 3.8 0.00046 18.9 2.7 1.3 1 0 0 1 1 1 1 Gammaherpesvirus latent membrane protein (LMP2) protein ORC6 PF05460.8 ETO08214.1 - 0.01 14.9 0.1 0.026 13.6 0.0 1.5 1 1 1 2 2 2 0 Origin recognition complex subunit 6 (ORC6) RGS PF00615.14 ETO08215.1 - 0.00066 19.7 0.0 0.00098 19.2 0.0 1.4 1 1 0 1 1 1 1 Regulator of G protein signaling domain Haemocyan_bet_s PF14830.1 ETO08215.1 - 0.011 15.3 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Haemocyanin beta-sandwich LMBR1 PF04791.11 ETO08216.1 - 0.012 14.1 2.4 0.022 13.3 1.7 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF1664 PF07889.7 ETO08216.1 - 1.3 8.8 27.1 1.8 8.3 6.9 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Peptidase_S21 PF00716.12 ETO08216.1 - 1.7 7.8 6.2 2.7 7.2 4.3 1.3 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) FAM117 PF15388.1 ETO08216.1 - 5.3 6.1 12.6 9.3 5.3 8.8 1.4 1 0 0 1 1 1 0 Protein Family FAM117 Abhydrolase_6 PF12697.2 ETO08217.1 - 1.3e-06 28.4 0.0 0.002 18.0 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETO08217.1 - 0.0031 16.7 0.1 0.024 13.8 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETO08217.1 - 0.0087 15.8 0.0 3 7.5 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Reo_sigmaC PF04582.7 ETO08218.1 - 0.00018 20.8 35.8 0.00021 20.5 2.4 5.0 2 1 1 5 5 5 4 Reovirus sigma C capsid protein ATG16 PF08614.6 ETO08218.1 - 0.00025 20.9 9.7 0.00025 20.9 6.7 6.0 2 1 3 6 6 6 2 Autophagy protein 16 (ATG16) DWNN PF08783.6 ETO08218.1 - 3.9 7.4 9.3 0.29 11.0 0.9 3.3 2 0 0 2 2 2 0 DWNN domain AAA_13 PF13166.1 ETO08218.1 - 5 5.4 95.9 0.012 14.0 22.2 4.3 2 1 2 4 4 4 0 AAA domain FANCI_S3 PF14677.1 ETO08220.1 - 0.094 12.0 4.5 0.087 12.1 2.6 1.3 1 1 0 1 1 1 0 FANCI solenoid 3 Pox_RNA_Pol_19 PF05320.7 ETO08220.1 - 0.1 12.3 3.0 0.11 12.2 2.1 1.0 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit EST1_DNA_bind PF10373.4 ETO08220.1 - 0.1 11.7 0.8 0.11 11.7 0.5 1.1 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain Sigma_reg_C PF13791.1 ETO08220.1 - 0.13 12.2 7.4 0.16 12.0 5.1 1.0 1 0 0 1 1 1 0 Sigma factor regulator C-terminal DUF1632 PF07857.7 ETO08220.1 - 0.34 10.1 1.3 0.39 9.9 0.9 1.0 1 0 0 1 1 1 0 CEO family (DUF1632) Paramyxo_NS_C PF02725.9 ETO08220.1 - 0.85 9.2 6.3 0.81 9.2 3.8 1.4 1 1 1 2 2 2 0 Non-structural protein C DUF843 PF05814.6 ETO08221.1 - 0.039 13.7 1.2 0.1 12.3 0.8 1.7 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) RhoGEF PF00621.15 ETO08223.1 - 5.7e-32 111.0 2.4 9.7e-32 110.2 1.7 1.4 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 ETO08223.1 - 0.019 15.1 0.2 0.081 13.1 0.0 2.0 2 0 0 2 2 2 0 PH domain CDC45 PF02724.9 ETO08224.1 - 0.13 10.2 2.5 0.21 9.6 1.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 ETO08224.1 - 2.4 5.9 9.4 2.4 5.9 6.5 1.2 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.13 ETO08224.1 - 3.4 6.7 14.1 0.044 12.9 4.7 1.6 2 0 0 2 2 2 0 Myc amino-terminal region Pox_RNA_Pol_19 PF05320.7 ETO08224.1 - 4.4 7.0 11.0 0.15 11.8 3.3 1.6 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Vac14_Fab1_bd PF12755.2 ETO08225.1 - 2e-20 72.9 2.5 2e-20 72.9 1.8 3.7 3 1 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 ETO08225.1 - 2.2e-10 39.7 3.2 0.00021 21.0 0.0 5.3 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 ETO08225.1 - 2.9e-09 37.0 0.0 0.031 14.5 0.0 4.3 3 1 2 5 5 5 4 HEAT repeats CLASP_N PF12348.3 ETO08225.1 - 0.00017 21.0 7.0 0.032 13.5 0.0 4.7 3 1 1 5 5 5 1 CLASP N terminal HEAT_EZ PF13513.1 ETO08225.1 - 0.00036 20.9 1.3 0.0073 16.7 0.0 3.8 5 0 0 5 5 5 1 HEAT-like repeat UME PF08064.8 ETO08225.1 - 0.015 15.2 1.4 0.22 11.4 0.2 3.1 2 2 0 2 2 2 0 UME (NUC010) domain RasGEF_N_2 PF14663.1 ETO08225.1 - 0.019 14.9 4.3 20 5.1 0.2 3.7 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Myc_N PF01056.13 ETO08225.1 - 0.39 9.8 6.0 0.77 8.8 4.2 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Yae1_N PF09811.4 ETO08226.1 - 0.011 15.2 16.4 0.65 9.5 0.1 6.1 6 2 1 7 7 7 0 Essential protein Yae1, N terminal Dynein_light PF01221.13 ETO08231.1 - 5.3e-06 26.3 0.1 7.7e-06 25.8 0.1 1.3 1 1 0 1 1 1 1 Dynein light chain type 1 TGS PF02824.16 ETO08232.1 - 1e-22 79.6 0.1 1.2e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 TGS domain VASP_tetra PF08776.6 ETO08232.1 - 0.19 11.0 1.3 0.35 10.2 0.9 1.4 1 0 0 1 1 1 0 VASP tetramerisation domain CENP-F_leu_zip PF10473.4 ETO08233.1 - 0.00024 20.9 5.0 0.00024 20.9 3.4 12.1 3 2 7 11 11 11 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.14 ETO08233.1 - 0.0032 17.0 21.1 0.0032 17.0 14.7 9.1 2 2 4 7 7 7 3 Ezrin/radixin/moesin family DUF4201 PF13870.1 ETO08233.1 - 0.0069 15.8 13.3 0.0069 15.8 9.2 11.2 4 3 5 10 10 10 2 Domain of unknown function (DUF4201) DUF4164 PF13747.1 ETO08233.1 - 0.042 13.9 0.4 0.042 13.9 0.3 12.0 6 4 7 14 14 14 0 Domain of unknown function (DUF4164) WD40 PF00400.27 ETO08234.1 - 6.8e-52 171.5 13.4 1.7e-09 37.1 0.0 7.0 6 1 1 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO08234.1 - 1.8e-09 36.3 2.5 0.27 9.3 0.0 5.5 3 1 3 6 6 6 5 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO08234.1 - 0.049 13.5 0.1 0.99 9.3 0.0 3.2 2 2 2 4 4 4 0 Domain of unknown function (DUF3601) Pkinase PF00069.20 ETO08236.1 - 4.9e-05 22.5 0.0 6.7e-05 22.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 ETO08237.1 - 3.6e-16 59.1 0.5 1.2e-12 47.5 0.1 3.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO08237.1 - 0.0001 21.4 0.1 0.001 18.2 0.1 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 ETO08237.1 - 0.044 13.1 0.0 0.044 13.1 0.0 3.2 3 1 1 4 4 4 0 RIO1 family Pox_A_type_inc PF04508.7 ETO08237.1 - 0.21 11.4 1.9 0.32 10.9 0.1 2.3 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Nup54 PF13874.1 ETO08237.1 - 2.5 7.7 11.8 1 9.0 6.0 1.9 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 CarboxypepD_reg PF13620.1 ETO08238.1 - 6.1e-11 42.2 0.0 4.7e-09 36.1 0.0 2.8 2 1 0 2 2 2 1 Carboxypeptidase regulatory-like domain Cna_B PF05738.8 ETO08238.1 - 0.00049 19.7 2.3 0.0021 17.7 0.0 2.7 3 0 0 3 3 3 1 Cna protein B-type domain Y_Y_Y PF07495.8 ETO08238.1 - 0.0006 19.5 0.0 0.0016 18.1 0.0 1.6 1 0 0 1 1 1 1 Y_Y_Y domain Dioxygenase_C PF00775.16 ETO08238.1 - 0.0012 18.1 0.1 0.017 14.3 0.0 2.6 3 0 0 3 3 3 1 Dioxygenase Atg14 PF10186.4 ETO08238.1 - 3.1 6.6 21.2 4.4 6.1 14.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF342 PF03961.8 ETO08238.1 - 5.6 5.2 17.5 8.9 4.5 12.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CAF-1_p150 PF11600.3 ETO08238.1 - 5.9 6.2 50.5 9.3 5.5 35.0 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal HAT PF02184.11 ETO08239.1 - 4.2e-15 55.1 27.7 0.00025 20.6 0.1 7.0 7 0 0 7 7 7 4 HAT (Half-A-TPR) repeat TPR_16 PF13432.1 ETO08239.1 - 1.7e-06 28.5 2.0 0.91 10.2 0.0 5.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO08239.1 - 2.8e-05 24.3 3.2 0.6 10.9 0.1 5.6 5 2 1 6 6 6 2 Tetratricopeptide repeat U3_assoc_6 PF08640.6 ETO08239.1 - 0.0043 16.7 15.9 0.26 11.0 0.1 4.5 3 3 1 4 4 4 2 U3 small nucleolar RNA-associated protein 6 TPR_19 PF14559.1 ETO08239.1 - 0.0046 17.2 0.1 21 5.5 0.0 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat Suf PF05843.9 ETO08239.1 - 0.0091 15.7 2.1 0.0091 15.7 1.5 3.5 2 2 1 3 3 3 1 Suppressor of forked protein (Suf) TPR_6 PF13174.1 ETO08239.1 - 1 9.9 5.7 34 5.1 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 ETO08239.1 - 2.8 8.3 5.1 8 6.9 0.3 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.27 ETO08240.1 - 3.4e-23 80.6 2.0 1.9e-10 40.1 0.2 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO08240.1 - 6.6e-05 21.2 0.0 0.023 12.8 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 WD40 PF00400.27 ETO08241.1 - 6.1e-65 212.9 19.7 2.2e-11 43.1 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO08241.1 - 1.5e-12 46.4 9.1 6.8e-05 21.1 0.5 5.5 2 2 4 6 6 6 5 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO08241.1 - 0.00078 19.7 2.3 0.0017 18.6 0.5 2.6 2 0 0 2 2 2 1 TRAF-type zinc finger Nucleoporin_N PF08801.6 ETO08241.1 - 0.0026 16.6 18.0 0.8 8.3 0.1 4.9 1 1 4 5 5 5 3 Nup133 N terminal like DUF3601 PF12208.3 ETO08241.1 - 0.011 15.6 2.6 0.45 10.4 0.0 4.2 4 1 1 5 5 5 0 Domain of unknown function (DUF3601) DUF3373 PF11853.3 ETO08241.1 - 0.18 10.3 7.6 0.35 9.3 5.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) TPR_19 PF14559.1 ETO08243.1 - 4.3e-06 26.9 0.1 0.013 15.7 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO08243.1 - 0.0032 17.5 2.5 0.013 15.6 1.3 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 ETO08243.1 - 0.0097 16.2 0.0 11 6.7 0.1 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO08243.1 - 0.011 16.2 0.2 0.94 10.2 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat U79_P34 PF03064.11 ETO08243.1 - 0.43 10.0 26.0 0.21 11.0 8.4 2.2 2 0 0 2 2 2 0 HSV U79 / HCMV P34 PLRV_ORF5 PF01690.12 ETO08243.1 - 3.6 6.6 17.3 0.2 10.7 6.1 2.0 2 0 0 2 2 2 0 Potato leaf roll virus readthrough protein Nucleoplasmin PF03066.10 ETO08243.1 - 8.6 5.8 21.4 0.1 12.1 2.7 2.6 2 0 0 2 2 2 0 Nucleoplasmin MIP-T3 PF10243.4 ETO08243.1 - 8.9 4.6 35.8 0.39 9.1 16.6 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Sec62 PF03839.11 ETO08243.1 - 8.9 5.6 22.6 2 7.7 10.0 2.3 2 0 0 2 2 2 0 Translocation protein Sec62 Thioredoxin PF00085.15 ETO08244.1 - 2.9e-23 81.5 1.4 4.7e-23 80.8 0.3 1.9 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 ETO08244.1 - 1.5e-05 24.9 2.9 0.004 17.2 0.0 4.5 3 2 1 4 4 4 1 Thioredoxin-like Thioredoxin_2 PF13098.1 ETO08244.1 - 0.0034 17.5 1.1 0.04 14.1 0.1 3.0 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 ETO08244.1 - 0.0036 17.3 0.3 0.041 13.9 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_3 PF13192.1 ETO08244.1 - 0.023 14.5 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain AhpC-TSA PF00578.16 ETO08244.1 - 0.098 12.3 0.4 0.74 9.5 0.2 2.6 2 1 0 2 2 2 0 AhpC/TSA family EF-hand_7 PF13499.1 ETO08245.1 - 3.4e-10 39.8 7.7 1.3e-06 28.3 0.3 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 ETO08245.1 - 1.3e-09 36.6 5.7 0.0012 17.9 0.0 4.2 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 ETO08245.1 - 4.4e-08 32.3 5.5 0.09 12.7 0.0 4.0 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.1 ETO08245.1 - 0.00073 19.0 3.6 0.61 9.7 0.1 3.1 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 ETO08245.1 - 0.016 14.4 2.9 1.1 8.7 0.0 3.4 4 0 0 4 4 4 0 EF hand DUF3306 PF11748.3 ETO08245.1 - 0.12 12.9 7.2 0.24 12.0 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Toprim_2 PF13155.1 ETO08245.1 - 0.17 12.2 0.1 0.17 12.2 0.0 2.5 2 1 1 4 4 4 0 Toprim-like Hydrolase_3 PF08282.7 ETO08245.1 - 0.53 9.8 3.3 1 8.8 2.3 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PX PF00787.19 ETO08245.1 - 0.55 10.0 6.1 0.29 10.9 1.2 2.8 2 1 0 2 2 2 0 PX domain DDRGK PF09756.4 ETO08245.1 - 0.62 9.4 15.0 5.2 6.4 9.7 2.6 2 1 0 2 2 2 0 DDRGK domain DUF2956 PF11169.3 ETO08247.1 - 0.37 10.7 4.8 1.3 8.9 3.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Tetraspannin PF00335.15 ETO08249.1 - 3e-05 23.4 2.1 3e-05 23.4 1.5 2.1 3 0 0 3 3 3 1 Tetraspanin family DUF659 PF04937.10 ETO08249.1 - 0.0076 15.7 2.6 0.11 12.0 1.8 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF 659) Kelch_6 PF13964.1 ETO08251.1 - 1e-06 28.6 1.5 0.07 13.3 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO08251.1 - 3.9e-06 26.3 1.1 0.0018 17.7 0.0 4.0 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.1 ETO08251.1 - 5.7e-05 22.8 1.1 0.35 10.6 0.1 4.2 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO08251.1 - 0.031 14.4 0.2 3.5 7.9 0.0 3.5 4 0 0 4 4 4 0 Galactose oxidase, central domain DUF3439 PF11921.3 ETO08252.1 - 0.018 14.7 10.2 0.045 13.4 7.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 ETO08252.1 - 0.16 11.7 17.7 0.3 10.8 12.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.6 ETO08252.1 - 0.72 7.7 15.2 0.98 7.3 10.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.7 ETO08252.1 - 0.9 7.2 11.0 0.029 12.1 3.4 1.5 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein COPI_C PF06957.6 ETO08253.1 - 0.0069 14.9 4.3 0.011 14.2 3.0 1.3 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Nop14 PF04147.7 ETO08254.1 - 0.00058 17.9 5.6 0.00076 17.5 3.9 1.3 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 ETO08254.1 - 0.019 13.5 11.1 0.024 13.1 7.7 1.3 1 0 0 1 1 1 0 Daxx Family Sporozoite_P67 PF05642.6 ETO08254.1 - 0.019 12.8 12.7 0.029 12.2 8.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2457 PF10446.4 ETO08254.1 - 0.027 13.2 18.1 0.043 12.5 12.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.7 ETO08254.1 - 0.039 13.2 9.1 0.053 12.8 6.3 1.2 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.7 ETO08254.1 - 0.2 10.8 13.9 0.37 10.0 9.6 1.5 1 0 0 1 1 1 0 NOA36 protein Utp14 PF04615.8 ETO08254.1 - 0.44 8.6 13.3 0.56 8.3 9.2 1.1 1 0 0 1 1 1 0 Utp14 protein Menin PF05053.8 ETO08254.1 - 0.46 8.5 11.6 0.79 7.8 8.0 1.4 1 0 0 1 1 1 0 Menin DUF506 PF04720.7 ETO08254.1 - 0.92 9.1 7.3 1.6 8.2 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF506) DUF1049 PF06305.6 ETO08255.1 - 0.036 13.5 1.4 0.094 12.2 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) DUF2681 PF10883.3 ETO08255.1 - 3.6 7.8 10.2 0.11 12.7 1.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) DUF4179 PF13786.1 ETO08256.1 - 0.0027 17.9 3.6 0.014 15.5 0.8 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4179) Bap31 PF05529.7 ETO08256.1 - 0.056 12.9 1.9 0.057 12.8 0.2 1.8 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like AgrB PF04647.10 ETO08256.1 - 1.1 8.3 8.6 5 6.1 2.1 2.4 2 0 0 2 2 2 0 Accessory gene regulator B DUF2116 PF09889.4 ETO08256.1 - 2.4 7.9 7.6 4.2 7.2 0.2 2.4 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DEP PF00610.16 ETO08257.1 - 1.2e-17 63.3 0.1 5e-09 35.7 0.0 2.4 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Clp_N PF02861.15 ETO08257.1 - 0.06 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Clp amino terminal domain zf-TRAF PF02176.13 ETO08258.1 - 4.6e-06 26.9 0.7 4.6e-06 26.9 0.5 3.6 4 0 0 4 4 4 2 TRAF-type zinc finger TPR_11 PF13414.1 ETO08259.1 - 4.7e-15 54.9 9.1 2.5e-09 36.6 0.8 4.1 3 1 1 4 4 4 3 TPR repeat TPR_2 PF07719.12 ETO08259.1 - 3.7e-13 48.2 7.7 0.014 15.2 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO08259.1 - 5.1e-12 44.8 8.8 0.00089 18.7 0.0 5.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO08259.1 - 5.8e-08 31.9 12.1 0.1 12.3 0.1 4.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETO08259.1 - 2.2e-06 27.4 8.3 0.0025 17.9 0.6 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO08259.1 - 5.1e-06 26.5 10.6 0.0023 18.0 3.8 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 ETO08259.1 - 6e-06 25.6 1.8 6.1 6.8 0.0 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO08259.1 - 1.1e-05 25.5 0.1 1.1 10.0 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO08259.1 - 4.6e-05 23.5 7.1 1.7 9.3 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO08259.1 - 0.00013 21.8 12.2 0.13 12.2 0.6 4.6 2 2 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO08259.1 - 0.0045 16.8 0.5 1.4 8.9 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO08259.1 - 0.0077 16.8 1.3 6 7.6 0.1 3.3 3 1 1 4 4 3 1 Tetratricopeptide repeat HEPN PF05168.9 ETO08259.1 - 0.05 13.4 0.6 0.05 13.4 0.4 2.2 3 1 0 3 3 3 0 HEPN domain CBM_15 PF03426.9 ETO08259.1 - 0.1 11.9 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain (family 15) Peptidase_S49_N PF08496.5 ETO08260.1 - 0.035 13.9 13.1 0.084 12.6 9.1 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal AAA_11 PF13086.1 ETO08260.1 - 0.14 11.7 3.5 0.19 11.2 2.5 1.3 1 0 0 1 1 1 0 AAA domain Chordopox_G3 PF06129.7 ETO08262.1 - 0.32 11.1 2.9 0.39 10.8 1.6 1.4 1 1 0 1 1 1 0 Chordopoxvirus G3 protein DUF755 PF05501.6 ETO08262.1 - 0.57 10.2 7.9 2.1 8.4 5.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF755) ERAP1_C PF11838.3 ETO08264.1 - 4e-09 36.1 0.6 8.9e-09 35.0 0.4 1.5 1 1 0 1 1 1 1 ERAP1-like C-terminal domain NAD_binding_9 PF13454.1 ETO08264.1 - 0.01 15.6 0.3 0.014 15.2 0.2 1.2 1 0 0 1 1 1 0 FAD-NAD(P)-binding DUF3256 PF11644.3 ETO08264.1 - 0.012 15.1 0.9 0.022 14.2 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3256) Peptidase_M1 PF01433.15 ETO08265.1 - 1.2e-05 24.6 0.0 1.4e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Serpin PF00079.15 ETO08266.1 - 2.5e-23 82.8 0.6 3e-23 82.5 0.4 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF1914 PF08932.5 ETO08266.1 - 0.008 16.1 0.1 0.015 15.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1914) RepC PF06504.6 ETO08266.1 - 0.03 13.2 0.0 0.25 10.2 0.0 2.0 2 0 0 2 2 2 0 Replication protein C (RepC) FR47 PF08445.5 ETO08266.1 - 0.15 11.8 0.2 0.42 10.3 0.0 1.8 2 0 0 2 2 2 0 FR47-like protein DUF4057 PF13266.1 ETO08270.1 - 0.036 13.5 0.4 0.049 13.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4057) WWE PF02825.15 ETO08271.1 - 0.019 14.3 0.0 0.076 12.4 0.0 2.0 2 0 0 2 2 2 0 WWE domain Imm22 PF15592.1 ETO08272.1 - 0.085 13.1 0.7 0.14 12.4 0.2 1.6 2 0 0 2 2 2 0 Immunity protein 22 Herpes_env PF01673.13 ETO08273.1 - 0.052 12.1 1.4 0.064 11.8 1.0 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein ASFV_360 PF01671.11 ETO08274.1 - 0.014 14.7 0.3 0.017 14.5 0.2 1.1 1 0 0 1 1 1 0 African swine fever virus multigene family 360 protein TMF_DNA_bd PF12329.3 ETO08276.1 - 0.00083 19.1 16.3 0.00083 19.1 11.3 3.4 3 0 0 3 3 3 2 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 ETO08276.1 - 0.0026 16.9 1.4 0.0037 16.4 1.0 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Filament PF00038.16 ETO08276.1 - 0.15 11.4 33.1 0.018 14.5 16.5 2.2 1 1 1 2 2 2 0 Intermediate filament protein Vac_Fusion PF02346.11 ETO08276.1 - 1.5 8.3 10.9 0.3 10.5 0.9 3.1 3 0 0 3 3 3 0 Chordopoxvirus fusion protein DUF940 PF06082.6 ETO08276.1 - 1.8 7.0 10.2 2.1 6.7 7.1 1.0 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) PhoU PF01895.14 ETO08276.1 - 3.2 8.2 19.6 7.1 7.1 1.2 3.6 1 1 1 3 3 3 0 PhoU domain Glyco_hydro_47 PF01532.15 ETO08277.1 - 1.5e-28 99.6 0.0 1.6e-28 99.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Ribosomal_S19e PF01090.14 ETO08278.1 - 3.4e-21 75.1 1.0 9.8e-18 63.9 0.0 2.7 3 1 0 3 3 3 2 Ribosomal protein S19e 5_nucleotid PF05761.9 ETO08278.1 - 0.04 12.4 0.1 0.12 10.9 0.0 1.7 2 0 0 2 2 2 0 5' nucleotidase family RHH_1 PF01402.16 ETO08278.1 - 0.075 12.9 0.2 1.6 8.7 0.0 2.8 2 1 1 3 3 3 0 Ribbon-helix-helix protein, copG family DUF2737 PF10930.3 ETO08279.1 - 0.24 11.0 1.6 1.3 8.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2737) PH PF00169.24 ETO08280.1 - 7.6e-09 35.7 0.7 9.4e-09 35.4 0.5 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 ETO08280.1 - 1.9e-05 24.8 1.7 3.3e-05 24.1 1.1 1.5 1 1 0 1 1 1 1 Pleckstrin homology domain Caps_synth PF05704.7 ETO08280.1 - 0.015 14.4 0.8 0.018 14.2 0.5 1.1 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Argos PF11581.3 ETO08281.1 - 0.0077 16.1 1.8 0.021 14.7 0.2 1.9 2 0 0 2 2 2 1 Antagonist of EGFR signalling, Argos MRAP PF15183.1 ETO08282.1 - 0.037 13.6 0.1 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family Cnd1_N PF12922.2 ETO08282.1 - 0.051 13.1 0.4 0.18 11.4 0.2 1.9 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term O-ag_pol_Wzy PF14296.1 ETO08282.1 - 0.054 12.0 0.1 0.07 11.7 0.1 1.1 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy RVT_1 PF00078.22 ETO08283.1 - 9.3e-15 54.5 0.0 1.7e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PAPA-1 PF04795.7 ETO08286.1 - 0.18 12.5 23.0 0.21 12.3 15.5 1.5 1 1 0 1 1 1 0 PAPA-1-like conserved region DUF2254 PF10011.4 ETO08288.1 - 0.074 11.5 0.4 2.4 6.5 0.1 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) zf-RanBP PF00641.13 ETO08289.1 - 0.00013 21.0 2.6 0.00037 19.5 1.8 1.9 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Pkinase PF00069.20 ETO08290.1 - 1.5e-40 139.0 0.3 1.5e-40 139.0 0.2 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO08290.1 - 1.6e-22 79.7 0.3 3.2e-22 78.8 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO08290.1 - 1.1e-07 31.1 0.5 2.7e-07 29.8 0.4 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO08290.1 - 5.3e-05 23.0 0.0 0.00069 19.4 0.0 2.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 ETO08290.1 - 0.0016 17.8 0.5 0.0053 16.1 0.0 2.1 3 0 0 3 3 3 1 PhoP regulatory network protein YrbL APH_6_hur PF04655.9 ETO08290.1 - 0.16 11.1 0.5 1.9 7.5 0.3 2.4 2 1 0 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Nucleoplasmin PF03066.10 ETO08290.1 - 1.4 8.4 12.4 0.32 10.4 5.3 2.1 2 0 0 2 2 2 0 Nucleoplasmin Myc_N PF01056.13 ETO08290.1 - 1.5 7.8 10.8 2.6 7.1 6.9 1.8 2 1 0 2 2 2 0 Myc amino-terminal region EF-hand_7 PF13499.1 ETO08291.1 - 9.7e-07 28.8 0.4 0.00036 20.6 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 ETO08291.1 - 0.00018 20.5 8.8 0.19 11.1 0.2 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 ETO08291.1 - 0.00077 19.1 4.3 1.1 9.3 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 ETO08291.1 - 0.0021 17.3 0.2 0.0021 17.3 0.2 3.1 3 0 0 3 3 3 1 EF hand OGG_N PF07934.7 ETO08291.1 - 0.12 12.3 0.2 0.32 10.9 0.0 1.8 1 1 1 2 2 2 0 8-oxoguanine DNA glycosylase, N-terminal domain Atrophin-1 PF03154.10 ETO08292.1 - 0.0043 15.2 9.6 0.0078 14.4 6.6 1.4 1 0 0 1 1 1 1 Atrophin-1 family Fmp27_WPPW PF10359.4 ETO08292.1 - 0.045 12.1 10.9 0.065 11.6 7.5 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF948 PF06103.6 ETO08292.1 - 0.081 12.7 1.8 0.22 11.4 1.3 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) CMV_1a PF12467.3 ETO08292.1 - 0.093 13.0 7.3 0.17 12.2 5.1 1.3 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family DivIVA PF05103.8 ETO08292.1 - 0.1 12.6 11.5 0.23 11.5 8.0 1.5 1 0 0 1 1 1 0 DivIVA protein DUF3584 PF12128.3 ETO08292.1 - 0.12 9.7 13.7 0.16 9.2 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1664 PF07889.7 ETO08292.1 - 0.38 10.5 6.6 0.26 11.0 3.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2956 PF11169.3 ETO08292.1 - 0.55 10.2 8.0 1.3 9.0 5.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) APG6 PF04111.7 ETO08292.1 - 0.57 9.1 15.4 0.95 8.4 10.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Cep57_CLD_2 PF14197.1 ETO08292.1 - 0.97 9.4 14.4 2.7 7.9 10.0 1.8 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 BTV_NS2 PF04514.7 ETO08292.1 - 1 8.2 15.2 1.7 7.4 10.5 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Bacillus_HBL PF05791.6 ETO08292.1 - 1.4 8.2 10.2 0.67 9.2 4.9 2.0 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) V_ATPase_I PF01496.14 ETO08292.1 - 2.1 6.0 9.6 3.4 5.4 6.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Synaptobrevin PF00957.16 ETO08292.1 - 2.2 7.9 8.6 3.6 7.2 4.0 2.3 2 0 0 2 2 2 0 Synaptobrevin ERM PF00769.14 ETO08292.1 - 4.7 6.6 23.9 0.13 11.7 12.3 1.5 2 0 0 2 2 1 0 Ezrin/radixin/moesin family Snf7 PF03357.16 ETO08294.1 - 2.2e-05 23.8 3.4 2.6e-05 23.6 2.4 1.1 1 0 0 1 1 1 1 Snf7 Ax_dynein_light PF10211.4 ETO08294.1 - 0.00067 19.5 0.8 0.00085 19.2 0.6 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain Med4 PF10018.4 ETO08294.1 - 0.0091 15.4 2.5 0.012 14.9 1.7 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Mnd1 PF03962.10 ETO08294.1 - 0.013 15.2 0.2 0.014 15.0 0.2 1.1 1 0 0 1 1 1 0 Mnd1 family Spc24 PF08286.6 ETO08294.1 - 0.013 15.1 0.0 0.016 14.8 0.0 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Prefoldin_2 PF01920.15 ETO08294.1 - 0.016 14.9 3.4 0.023 14.4 2.3 1.2 1 0 0 1 1 1 0 Prefoldin subunit YkyA PF10368.4 ETO08294.1 - 0.019 14.2 2.0 0.024 13.9 1.4 1.1 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein DivIC PF04977.10 ETO08294.1 - 0.021 14.3 2.9 0.04 13.4 2.0 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF3338 PF11819.3 ETO08294.1 - 0.022 14.2 0.6 0.028 13.8 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3338) Atg14 PF10186.4 ETO08294.1 - 0.027 13.4 0.9 0.034 13.0 0.6 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMCO5 PF14992.1 ETO08294.1 - 0.035 13.2 1.0 0.041 13.0 0.7 1.0 1 0 0 1 1 1 0 TMCO5 family Prefoldin PF02996.12 ETO08294.1 - 0.042 13.4 2.4 0.053 13.1 1.7 1.2 1 0 0 1 1 1 0 Prefoldin subunit Hanta_nucleocap PF00846.13 ETO08294.1 - 0.05 12.3 0.4 0.056 12.1 0.3 1.0 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein TBPIP PF07106.8 ETO08294.1 - 0.06 12.8 2.0 0.074 12.5 1.4 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) UPF0184 PF03670.8 ETO08294.1 - 0.073 13.2 0.1 0.092 12.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) DUF812 PF05667.6 ETO08294.1 - 0.076 11.5 1.2 0.087 11.3 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DisA-linker PF10635.4 ETO08294.1 - 0.1 12.1 0.1 0.13 11.7 0.1 1.1 1 0 0 1 1 1 0 DisA bacterial checkpoint controller linker region CALCOCO1 PF07888.6 ETO08294.1 - 0.1 10.8 0.7 0.12 10.6 0.5 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ATG16 PF08614.6 ETO08294.1 - 0.12 12.1 2.5 0.14 11.9 1.7 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.3 ETO08294.1 - 0.27 11.0 7.3 0.53 10.1 5.1 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.7 ETO08294.1 - 0.62 10.4 4.8 1.5 9.2 3.3 1.5 1 1 1 2 2 2 0 SlyX XhlA PF10779.4 ETO08294.1 - 1.5 8.8 4.0 2.4 8.1 2.8 1.4 1 1 0 1 1 1 0 Haemolysin XhlA DUF972 PF06156.8 ETO08294.1 - 6.3 7.1 8.3 3.1 8.1 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Homoserine_dh PF00742.14 ETO08295.1 - 7.2e-37 126.7 0.0 3.5e-28 98.4 0.0 2.3 2 0 0 2 2 2 2 Homoserine dehydrogenase ELFV_dehydrog PF00208.16 ETO08295.1 - 0.00017 21.2 0.1 0.00055 19.5 0.0 1.8 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DXP_reductoisom PF02670.11 ETO08295.1 - 0.0011 19.5 0.1 0.0032 18.0 0.0 1.8 1 1 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase NAD_binding_3 PF03447.11 ETO08295.1 - 0.0011 19.3 0.0 0.008 16.5 0.0 2.2 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain NAF PF03822.9 ETO08295.1 - 0.073 12.7 0.8 0.17 11.5 0.2 1.9 2 0 0 2 2 2 0 NAF domain ADK PF00406.17 ETO08296.1 - 1.4e-19 70.5 0.1 3.6e-19 69.1 0.0 1.6 1 1 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 ETO08296.1 - 6.3e-11 42.6 0.1 8.7e-11 42.2 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO08296.1 - 1e-10 42.4 0.0 1.5e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 ETO08296.1 - 0.0012 18.9 0.0 0.0018 18.5 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 ETO08296.1 - 0.0023 18.0 0.0 0.0047 17.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.1 ETO08296.1 - 0.0031 17.6 0.0 0.005 16.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.10 ETO08296.1 - 0.0041 15.8 0.0 0.0051 15.5 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_24 PF13479.1 ETO08296.1 - 0.0057 16.2 0.0 0.0081 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 ETO08296.1 - 0.0096 15.6 0.0 0.018 14.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 ETO08296.1 - 0.0097 15.9 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.1 ETO08296.1 - 0.014 15.3 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 ETO08296.1 - 0.015 15.0 0.1 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 NTPase Sigma54_activ_2 PF14532.1 ETO08296.1 - 0.016 15.2 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 ETO08296.1 - 0.028 14.7 0.0 0.036 14.3 0.0 1.2 1 0 0 1 1 1 0 ABC transporter VirE PF05272.6 ETO08296.1 - 0.028 13.8 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E Zeta_toxin PF06414.7 ETO08296.1 - 0.03 13.3 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin CoaE PF01121.15 ETO08296.1 - 0.039 13.3 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_29 PF13555.1 ETO08296.1 - 0.054 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Thymidylate_kin PF02223.12 ETO08296.1 - 0.071 12.4 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 Thymidylate kinase TIP49 PF06068.8 ETO08296.1 - 0.079 11.6 0.1 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus ArgK PF03308.11 ETO08296.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 ArgK protein MMR_HSR1 PF01926.18 ETO08296.1 - 0.12 12.3 0.1 0.17 11.8 0.1 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.1 ETO08296.1 - 0.13 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rep_fac-A_C PF08646.5 ETO08297.1 - 1.3e-32 112.4 4.1 3.3e-31 107.9 0.1 3.8 4 0 0 4 4 4 1 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 ETO08297.1 - 7.2e-15 54.6 0.5 6.2e-09 35.5 0.1 3.4 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain Rep-A_N PF04057.7 ETO08297.1 - 1.2e-13 50.6 0.8 1.2e-10 41.0 0.3 2.7 2 0 0 2 2 2 2 Replication factor-A protein 1, N-terminal domain EF-hand_7 PF13499.1 ETO08298.1 - 1.1e-16 60.7 4.5 2.1e-07 30.9 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 ETO08298.1 - 1.9e-15 54.9 6.7 8.9e-07 27.7 0.4 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 ETO08298.1 - 2.2e-12 45.7 4.3 4.3e-05 23.0 0.3 4.0 3 1 1 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 ETO08298.1 - 5.7e-10 38.0 11.5 4.9e-05 22.4 0.3 4.1 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 ETO08298.1 - 5.7e-08 32.2 7.5 6.5e-05 22.4 0.4 3.7 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 ETO08298.1 - 0.00053 19.9 1.3 2.3 8.2 0.0 3.1 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Pkinase PF00069.20 ETO08298.1 - 0.0076 15.4 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 ETO08300.1 - 2.4e-67 220.5 16.4 2.4e-11 43.0 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO08300.1 - 1.6e-12 47.5 1.7 3.3e-07 30.1 0.4 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO08300.1 - 6.8e-10 37.6 8.5 0.0094 14.1 0.0 4.3 1 1 3 4 4 4 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO08300.1 - 1.3e-06 28.0 0.7 7.8e-06 25.5 0.1 2.1 1 1 1 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO08300.1 - 3e-05 22.5 2.1 0.11 10.7 0.0 3.2 1 1 2 3 3 3 2 Cytochrome D1 heme domain Gmad1 PF10647.4 ETO08300.1 - 9.8e-05 21.8 0.0 0.27 10.5 0.0 3.1 1 1 1 3 3 3 2 Lipoprotein LpqB beta-propeller domain Nbas_N PF15492.1 ETO08300.1 - 0.0038 16.3 1.3 1.5 7.8 0.1 3.3 1 1 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal DUF1258 PF06869.7 ETO08300.1 - 0.01 14.9 0.3 4.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1258) Str_synth PF03088.11 ETO08300.1 - 0.012 15.6 0.2 0.68 9.9 0.0 3.1 3 1 0 3 3 3 0 Strictosidine synthase Coatomer_WDAD PF04053.9 ETO08300.1 - 0.13 11.0 1.8 1.9 7.1 0.0 2.3 1 1 0 2 2 2 0 Coatomer WD associated region F_actin_cap_B PF01115.12 ETO08302.1 - 2e-50 171.2 0.9 6.6e-50 169.5 0.6 1.7 1 1 0 1 1 1 1 F-actin capping protein, beta subunit DUSP PF06337.7 ETO08303.1 - 2.4e-11 43.9 0.1 4.4e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 DUSP domain DUF3807 PF12720.2 ETO08304.1 - 1.3 9.1 18.7 1.9 8.6 12.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Neur_chan_memb PF02932.11 ETO08304.1 - 2.7 7.8 12.5 3.3 7.5 8.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1675 PF07897.6 ETO08304.1 - 3 7.6 21.9 3.3 7.4 15.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF572 PF04502.8 ETO08304.1 - 4.9 6.2 25.6 6 5.9 17.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Asp-B-Hydro_N PF05279.6 ETO08304.1 - 6.4 6.5 14.2 7.6 6.3 9.8 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2201_N PF13203.1 ETO08304.1 - 7.2 5.6 12.6 8.7 5.4 8.7 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF966 PF06136.8 ETO08304.1 - 8.8 5.6 25.0 10 5.4 17.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Miff PF05644.6 ETO08304.1 - 9.2 5.8 13.2 12 5.4 9.1 1.1 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Menin PF05053.8 ETO08305.1 - 0.41 8.7 12.4 0.5 8.4 8.6 1.1 1 0 0 1 1 1 0 Menin DUF605 PF04652.11 ETO08305.1 - 0.93 8.8 18.2 1.2 8.4 12.6 1.1 1 0 0 1 1 1 0 Vta1 like Mem_trans PF03547.13 ETO08305.1 - 3.3 5.9 6.7 3.8 5.7 4.7 1.3 1 0 0 1 1 1 0 Membrane transport protein Paramyxo_ncap PF00973.14 ETO08305.1 - 6.3 5.3 10.6 7.2 5.1 7.3 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Laminin_G_3 PF13385.1 ETO08306.1 - 0.0011 19.1 0.9 0.0019 18.4 0.6 1.4 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Rax2 PF12768.2 ETO08306.1 - 0.015 14.5 2.1 0.018 14.2 1.5 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity TLD PF07534.11 ETO08309.1 - 1.2e-27 96.5 0.5 2.9e-27 95.3 0.2 1.8 2 0 0 2 2 2 1 TLD Tetraspannin PF00335.15 ETO08310.1 - 0.0015 17.8 0.7 0.0015 17.8 0.5 2.9 3 0 0 3 3 3 1 Tetraspanin family DUF912 PF06024.7 ETO08310.1 - 0.0022 18.0 1.4 0.0022 18.0 0.9 4.6 4 0 0 4 4 4 2 Nucleopolyhedrovirus protein of unknown function (DUF912) Shisa PF13908.1 ETO08310.1 - 0.0065 16.6 1.0 0.054 13.6 0.5 2.5 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator Rifin_STEVOR PF02009.11 ETO08310.1 - 0.0099 15.5 10.2 0.14 11.8 3.3 2.6 2 0 0 2 2 2 2 Rifin/stevor family TMEM154 PF15102.1 ETO08310.1 - 0.011 15.4 0.8 0.011 15.4 0.5 3.0 3 0 0 3 3 3 0 TMEM154 protein family Pico_P2B PF01552.12 ETO08310.1 - 0.11 12.6 3.6 0.25 11.5 2.5 1.5 1 0 0 1 1 1 0 Picornavirus 2B protein Peptidase_S49_N PF08496.5 ETO08310.1 - 0.13 12.0 0.2 0.35 10.6 0.0 1.8 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF4446 PF14584.1 ETO08310.1 - 1.4 8.6 7.9 0.88 9.3 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Marek_A PF02124.10 ETO08310.1 - 1.8 7.9 6.5 4.7 6.6 2.5 2.3 2 0 0 2 2 2 0 Marek's disease glycoprotein A EphA2_TM PF14575.1 ETO08310.1 - 4.8 7.6 14.8 40 4.7 6.8 3.7 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Coprogen_oxidas PF01218.13 ETO08311.1 - 6.3e-75 251.4 0.4 3e-74 249.2 0.3 1.9 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase NKAIN PF05640.9 ETO08312.1 - 0.029 13.3 9.7 0.052 12.5 6.7 1.3 1 0 0 1 1 1 0 Na,K-Atpase Interacting protein Pkinase PF00069.20 ETO08314.1 - 3.4e-07 29.6 0.7 4e-07 29.4 0.5 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO08314.1 - 8.6e-06 25.0 0.1 8.8e-06 24.9 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.27 ETO08316.1 - 1.7e-58 192.5 17.8 1.6e-10 40.4 0.2 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO08316.1 - 1.4e-15 56.4 3.2 0.016 13.3 0.0 6.0 2 1 4 6 6 6 6 Nucleoporin Nup120/160 HAD PF12710.2 ETO08316.1 - 0.34 11.0 1.9 19 5.3 0.0 3.3 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase WD40 PF00400.27 ETO08317.1 - 2.9e-42 141.0 7.3 3.6e-10 39.3 0.1 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO08317.1 - 2.5e-05 22.6 0.8 1.4 6.9 0.0 4.2 1 1 3 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO08317.1 - 0.0003 19.6 7.6 0.012 14.3 3.6 2.7 1 1 1 2 2 2 2 Nup133 N terminal like YyzF PF14116.1 ETO08318.1 - 0.059 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 YyzF-like protein Pox_E10 PF04805.7 ETO08319.1 - 0.037 13.5 0.6 0.037 13.5 0.4 2.1 1 1 1 2 2 2 0 E10-like protein conserved region Pox_E8 PF03394.8 ETO08320.1 - 0.081 12.2 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus E8 protein EPO_TPO PF00758.13 ETO08320.1 - 0.096 12.3 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Erythropoietin/thrombopoietin UpxZ PF06603.6 ETO08320.1 - 0.1 12.6 0.7 0.59 10.1 0.2 2.2 1 1 1 2 2 2 0 UpxZ family of transcription anti-terminator antagonists HSP70 PF00012.15 ETO08321.1 - 1.5e-119 399.6 4.2 9e-97 324.4 1.1 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 ETO08321.1 - 3.6e-10 38.9 0.0 6.2e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Kei1 PF08552.6 ETO08322.1 - 0.022 14.3 0.5 0.024 14.2 0.4 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 PPR PF01535.15 ETO08324.1 - 7.6e-11 41.2 7.2 0.088 12.8 0.1 5.1 5 0 0 5 5 5 4 PPR repeat PPR_2 PF13041.1 ETO08324.1 - 3.5e-09 36.5 8.5 0.003 17.4 0.4 4.5 2 1 3 5 5 5 4 PPR repeat family PPR_3 PF13812.1 ETO08324.1 - 5.7e-08 32.4 0.0 0.043 14.1 0.0 5.1 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 ETO08324.1 - 0.023 14.1 1.7 4.6 6.8 0.0 3.6 4 0 0 4 4 4 0 PPR repeat SAND PF01342.16 ETO08324.1 - 0.089 12.5 1.3 0.39 10.4 0.2 2.6 3 0 0 3 3 3 0 SAND domain ChaC PF04752.7 ETO08325.1 - 5.6e-47 159.9 0.0 6.8e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein AIG2 PF06094.7 ETO08325.1 - 0.00067 20.1 0.0 0.00097 19.5 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family DUF1129 PF06570.6 ETO08325.1 - 0.004 16.4 0.6 0.007 15.6 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) AIG2_2 PF13772.1 ETO08325.1 - 0.0062 16.6 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family 7TM_GPCR_Srb PF02175.11 ETO08326.1 - 0.02 14.4 10.2 0.56 9.7 1.5 2.8 2 1 1 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srb NdhL PF10716.4 ETO08326.1 - 0.56 10.0 7.8 0.22 11.3 0.4 3.1 2 1 1 3 3 3 0 NADH dehydrogenase transmembrane subunit DUF1266 PF06889.6 ETO08327.1 - 0.022 14.5 0.4 0.044 13.5 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1266) DUF3069 PF11269.3 ETO08328.1 - 0.2 11.7 3.8 9 6.4 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3069) DUF1690 PF07956.6 ETO08328.1 - 0.94 9.4 11.4 0.056 13.4 2.8 2.5 3 1 1 4 4 4 0 Protein of Unknown function (DUF1690) Amidinotransf PF02274.12 ETO08329.1 - 0.021 13.9 1.8 0.045 12.8 0.0 2.0 1 1 0 2 2 2 0 Amidinotransferase V-SNARE PF05008.10 ETO08329.1 - 0.77 9.9 0.0 0.77 9.9 0.0 3.8 5 0 0 5 5 5 0 Vesicle transport v-SNARE protein N-terminus IMPDH PF00478.20 ETO08330.1 - 2.7e-32 112.0 0.2 3.1e-32 111.8 0.1 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain IMPDH PF00478.20 ETO08331.1 - 5.7e-66 222.8 1.4 6.4e-66 222.6 1.0 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 ETO08331.1 - 2e-15 56.2 0.0 1.7e-07 30.9 0.0 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 ETO08331.1 - 0.00029 19.7 1.2 0.00053 18.9 0.8 1.4 1 1 0 1 1 1 1 FMN-dependent dehydrogenase PK PF00224.16 ETO08331.1 - 0.0033 16.1 0.0 0.0048 15.5 0.0 1.3 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain B12-binding PF02310.14 ETO08331.1 - 0.0082 16.0 0.1 0.014 15.3 0.1 1.3 1 0 0 1 1 1 1 B12 binding domain His_biosynth PF00977.16 ETO08331.1 - 0.012 14.8 0.5 1.1 8.4 0.0 2.5 1 1 0 1 1 1 0 Histidine biosynthesis protein NMO PF03060.10 ETO08331.1 - 0.014 14.5 2.3 0.026 13.7 0.4 1.9 2 0 0 2 2 2 0 Nitronate monooxygenase DUF1273 PF06908.6 ETO08331.1 - 0.041 13.5 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) PEP_mutase PF13714.1 ETO08331.1 - 0.08 12.1 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Cation_ATPase_C PF00689.16 ETO08333.1 - 5.5e-17 61.8 5.7 5.5e-17 61.8 3.9 2.6 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus DUF2367 PF10164.4 ETO08333.1 - 1.1 9.1 6.7 2.6 7.9 4.7 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) GNT-I PF03071.10 ETO08334.1 - 0.12 10.8 0.6 0.16 10.5 0.4 1.1 1 0 0 1 1 1 0 GNT-I family DUF1119 PF06550.6 ETO08335.1 - 0.0094 15.1 0.6 0.01 14.9 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1119) DUF502 PF04367.8 ETO08335.1 - 0.04 13.6 0.0 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF502) FixQ PF05545.6 ETO08335.1 - 0.11 12.1 0.2 0.29 10.7 0.1 1.7 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ RIC3 PF15361.1 ETO08335.1 - 0.24 11.6 1.4 0.36 11.0 0.9 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 YoqO PF14037.1 ETO08335.1 - 0.35 10.9 6.0 1.9 8.6 4.5 1.9 1 1 1 2 2 2 0 YoqO-like protein RELT PF12606.3 ETO08335.1 - 1.5 7.9 5.0 2.8 7.1 3.5 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 CAP_GLY PF01302.20 ETO08339.1 - 1.2e-32 111.4 3.1 1.2e-18 66.5 0.1 2.3 2 0 0 2 2 2 2 CAP-Gly domain BACK PF07707.10 ETO08339.1 - 7.7e-07 28.9 0.2 0.00043 20.0 0.1 2.7 2 0 0 2 2 2 2 BTB And C-terminal Kelch DUF4306 PF14154.1 ETO08340.1 - 0.18 11.7 4.4 0.12 12.3 1.5 1.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4306) RNR_N PF08343.5 ETO08341.1 - 0.053 13.3 2.3 0.14 11.9 1.6 1.7 1 1 0 1 1 1 0 Ribonucleotide reductase N-terminal TMEM138 PF14935.1 ETO08341.1 - 0.072 13.4 2.6 0.066 13.5 1.0 1.5 2 0 0 2 2 2 0 Transmembrane protein 138 EAP30 PF04157.11 ETO08341.1 - 0.086 11.9 2.2 0.21 10.7 0.6 1.9 1 1 1 2 2 2 0 EAP30/Vps36 family Kelch_2 PF07646.10 ETO08344.1 - 1.7e-07 30.7 1.7 0.0034 17.0 0.2 4.3 4 1 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO08344.1 - 4.3e-07 29.3 0.9 0.00027 20.3 0.1 4.1 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 ETO08344.1 - 4.7e-07 29.7 2.8 0.066 13.4 0.2 4.7 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.1 ETO08344.1 - 1.4e-05 24.7 0.3 0.027 14.2 0.0 3.4 2 1 1 3 3 3 2 Galactose oxidase, central domain Serpin PF00079.15 ETO08345.1 - 9.2e-13 48.0 0.8 1e-12 47.9 0.6 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF2098 PF09871.4 ETO08345.1 - 0.04 13.8 1.5 0.087 12.7 0.4 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) Serpin PF00079.15 ETO08346.1 - 1.6e-23 83.4 0.0 1.7e-23 83.3 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) MIF4G PF02854.14 ETO08347.1 - 9.9e-09 34.9 5.5 1.2e-07 31.4 1.2 3.0 3 0 0 3 3 3 1 MIF4G domain FlaG PF03646.10 ETO08347.1 - 0.74 9.9 0.1 0.74 9.9 0.0 2.6 4 0 0 4 4 4 0 FlaG protein Glyco_transf_92 PF01697.22 ETO08348.1 - 3.1e-09 36.5 6.8 5.3e-09 35.7 4.7 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.1 ETO08348.1 - 0.00022 21.4 1.9 0.00068 19.9 1.3 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 2 MIF4G PF02854.14 ETO08349.1 - 0.081 12.3 5.0 0.061 12.7 0.7 2.5 3 0 0 3 3 3 0 MIF4G domain GST_N_3 PF13417.1 ETO08350.1 - 5.9e-15 55.2 0.0 1.3e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 ETO08350.1 - 4.6e-12 45.9 0.0 7.9e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETO08350.1 - 2.7e-10 40.1 0.0 4.3e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 ETO08350.1 - 9.7e-08 31.9 0.0 1.8e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETO08350.1 - 6.4e-05 22.7 0.0 9.5e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 ETO08350.1 - 0.0017 18.7 0.0 0.0028 18.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SET PF00856.23 ETO08351.1 - 4.8e-12 46.4 1.2 1e-11 45.3 0.0 2.1 2 0 0 2 2 2 1 SET domain Secretin_N_2 PF07655.8 ETO08351.1 - 0.16 12.3 9.3 0.28 11.5 3.9 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain Fer4_9 PF13187.1 ETO08352.1 - 0.042 14.1 0.4 0.1 12.8 0.0 1.8 2 0 0 2 2 2 0 4Fe-4S dicluster domain EphA2_TM PF14575.1 ETO08352.1 - 0.21 11.9 2.0 0.35 11.3 0.0 2.2 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain API5 PF05918.6 ETO08353.1 - 0.00063 18.3 11.2 0.00085 17.9 7.8 1.2 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) GRP PF07172.6 ETO08353.1 - 0.085 13.3 11.7 0.15 12.5 8.1 1.5 1 0 0 1 1 1 0 Glycine rich protein family Kelch_1 PF01344.20 ETO08354.1 - 4.1e-05 23.0 3.3 0.0011 18.4 0.2 2.6 3 0 0 3 3 3 2 Kelch motif Fumble PF03630.9 ETO08354.1 - 0.022 13.5 0.4 0.03 13.1 0.3 1.2 1 0 0 1 1 1 0 Fumble Kelch_2 PF07646.10 ETO08354.1 - 0.027 14.2 1.0 0.42 10.4 0.1 2.6 2 1 0 2 2 2 0 Kelch motif Kelch_6 PF13964.1 ETO08354.1 - 0.036 14.2 0.6 0.45 10.7 0.2 2.3 2 0 0 2 2 2 0 Kelch motif Kelch_5 PF13854.1 ETO08354.1 - 0.064 13.2 0.5 1.5 8.8 0.1 2.8 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.1 ETO08354.1 - 0.15 11.8 0.1 6.9 6.5 0.0 2.6 2 0 0 2 2 2 0 Galactose oxidase, central domain WD40 PF00400.27 ETO08355.1 - 8.5e-21 73.0 11.4 1.5e-12 46.9 0.2 4.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO08355.1 - 1.3e-05 23.6 1.1 0.11 10.6 0.1 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO08355.1 - 0.021 13.5 2.8 2.5 6.7 0.0 2.7 1 1 1 2 2 2 0 Nup133 N terminal like BBS2_Mid PF14783.1 ETO08355.1 - 0.37 10.5 1.9 17 5.1 0.3 2.3 1 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.27 ETO08356.1 - 2.4e-07 30.3 1.7 9.8e-05 22.0 0.3 2.8 2 1 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO08356.1 - 0.043 11.9 0.0 0.043 11.9 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 UpxZ PF06603.6 ETO08356.1 - 0.12 12.3 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 UpxZ family of transcription anti-terminator antagonists DUF2677 PF10838.3 ETO08356.1 - 0.13 11.8 0.2 0.3 10.7 0.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2677) DUF3625 PF12293.3 ETO08357.1 - 0.008 15.3 0.0 0.01 14.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3625) PT PF04886.7 ETO08359.1 - 6.8e-05 22.0 45.2 0.00046 19.4 2.9 4.9 2 1 0 2 2 2 1 PT repeat Ste5 PF11610.3 ETO08359.1 - 1.6 8.3 9.0 6.5 6.3 0.2 3.8 2 1 2 4 4 4 0 Scaffold protein Ste5-Fus5 binding region Init_tRNA_PT PF04179.7 ETO08361.1 - 7.7e-05 21.7 3.1 9.7e-05 21.4 2.1 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Prp18 PF02840.10 ETO08361.1 - 0.026 14.3 6.5 0.037 13.8 4.5 1.3 1 0 0 1 1 1 0 Prp18 domain CDC37_N PF03234.9 ETO08361.1 - 0.044 14.0 10.1 0.056 13.7 7.0 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding ABC2_membrane_3 PF12698.2 ETO08361.1 - 0.055 12.4 3.2 0.081 11.9 2.2 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein BAR PF03114.13 ETO08361.1 - 0.061 12.8 9.7 0.064 12.7 1.2 1.9 1 1 1 2 2 2 0 BAR domain DUF2877 PF11392.3 ETO08361.1 - 0.26 11.5 2.7 0.34 11.1 1.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2877) DUF789 PF05623.7 ETO08361.1 - 0.51 9.7 2.8 0.65 9.4 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF789) DUF2309 PF10070.4 ETO08361.1 - 0.53 8.3 5.1 0.62 8.0 3.6 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) DUF4559 PF15112.1 ETO08361.1 - 0.59 9.2 14.0 0.78 8.8 9.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) TipAS PF07739.8 ETO08361.1 - 0.64 10.3 2.6 0.58 10.4 0.6 1.7 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain DUF1700 PF08006.6 ETO08361.1 - 2.1 7.6 5.3 3.5 6.8 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF445 PF04286.7 ETO08361.1 - 2.6 7.4 10.1 3.2 7.1 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) UPF0118 PF01594.11 ETO08361.1 - 7.2 5.4 10.3 0.87 8.5 3.3 1.8 1 1 1 2 2 2 0 Domain of unknown function DUF20 HSBP1 PF06825.7 ETO08361.1 - 7.8 6.1 7.7 8.7 6.0 0.1 3.3 3 1 0 3 3 3 0 Heat shock factor binding protein 1 Peptidase_M22 PF00814.20 ETO08362.1 - 0.086 12.3 0.1 0.2 11.1 0.0 1.5 2 0 0 2 2 2 0 Glycoprotease family Spore_coat_CotO PF14153.1 ETO08362.1 - 0.52 9.7 12.5 1.3 8.4 8.7 1.6 1 0 0 1 1 1 0 Spore coat protein CotO Virulence_fact PF13769.1 ETO08363.1 - 0.0083 15.9 0.4 0.019 14.8 0.3 1.6 1 0 0 1 1 1 1 Virulence factor Serine_rich PF08824.5 ETO08363.1 - 0.049 13.3 2.3 0.095 12.4 1.6 1.4 1 0 0 1 1 1 0 Serine rich protein interaction domain DUF3323 PF11796.3 ETO08363.1 - 0.08 12.2 4.4 0.12 11.6 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) SAM_2 PF07647.12 ETO08363.1 - 0.09 12.6 2.1 0.65 9.8 0.0 3.0 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) Sec8_exocyst PF04048.9 ETO08363.1 - 0.091 12.3 5.0 0.15 11.6 3.0 1.7 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain KxDL PF10241.4 ETO08363.1 - 0.2 11.5 6.3 0.14 12.0 1.3 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein GvpL_GvpF PF06386.6 ETO08363.1 - 0.35 10.4 5.3 0.62 9.6 3.7 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF YtxH PF12732.2 ETO08363.1 - 1.5 9.2 6.9 10 6.5 0.1 2.9 3 0 0 3 3 3 0 YtxH-like protein IncA PF04156.9 ETO08363.1 - 8.2 5.9 9.2 16 5.0 6.4 1.5 1 0 0 1 1 1 0 IncA protein OmpH PF03938.9 ETO08363.1 - 8.6 6.2 13.8 2.2 8.2 7.1 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) IstB_IS21 PF01695.12 ETO08364.1 - 0.034 13.5 0.1 0.046 13.1 0.1 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein Hormone_6 PF00236.13 ETO08364.1 - 0.058 13.2 4.6 0.078 12.8 1.5 2.2 2 1 1 3 3 3 0 Glycoprotein hormone Vasohibin PF14822.1 ETO08364.1 - 0.072 12.1 0.4 0.1 11.6 0.1 1.4 2 0 0 2 2 2 0 Vasohibin DUF2368 PF10166.4 ETO08365.1 - 0.36 10.4 4.8 1.1 8.8 3.3 1.9 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) WD40 PF00400.27 ETO08366.1 - 7.2e-63 206.3 26.9 1.9e-11 43.3 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO08366.1 - 1.1e-10 40.2 5.0 0.48 8.4 0.0 5.7 2 2 3 6 6 6 5 Nucleoporin Nup120/160 WD40 PF00400.27 ETO08367.1 - 2.3e-08 33.5 0.9 4e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF2651 PF10852.3 ETO08367.1 - 0.14 12.4 4.8 0.26 11.6 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2651) WD40 PF00400.27 ETO08368.1 - 1e-60 199.5 9.3 5.4e-13 48.2 0.2 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 ETO08368.1 - 4.3e-10 39.6 0.2 1.3e-05 25.0 0.0 3.1 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO08368.1 - 3.7e-08 31.9 0.7 0.017 13.2 0.2 3.5 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO08368.1 - 7.4e-06 24.5 1.5 0.041 12.1 0.1 3.3 1 1 2 3 3 3 3 Cytochrome D1 heme domain PD40 PF07676.7 ETO08368.1 - 8.6e-05 22.1 1.1 15 5.3 0.0 4.7 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO08368.1 - 0.00026 19.8 4.6 0.48 9.1 0.0 3.8 1 1 3 4 4 4 2 Nup133 N terminal like BBS2_Mid PF14783.1 ETO08368.1 - 0.0013 18.4 2.7 1.1 8.9 0.1 4.0 2 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region DUF1258 PF06869.7 ETO08368.1 - 0.0014 17.7 0.5 6.2 5.8 0.0 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF1258) Proteasome_A_N PF10584.4 ETO08368.1 - 0.0024 17.1 0.2 7.7 5.9 0.0 4.2 4 0 0 4 4 4 1 Proteasome subunit A N-terminal signature Str_synth PF03088.11 ETO08368.1 - 0.023 14.7 0.1 0.42 10.6 0.0 2.8 3 0 0 3 3 3 0 Strictosidine synthase SGL PF08450.7 ETO08368.1 - 0.024 14.0 0.1 1.2 8.4 0.0 2.4 2 0 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region DPPIV_N PF00930.16 ETO08368.1 - 0.053 12.0 0.0 7.4 5.0 0.0 3.0 3 0 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region TFIIIC_delta PF12657.2 ETO08368.1 - 0.07 12.8 0.5 6 6.5 0.0 2.3 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term EF-hand_1 PF00036.27 ETO08369.1 - 0.0042 16.2 0.1 0.0095 15.1 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 ETO08369.1 - 0.0079 16.0 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 ETO08369.1 - 0.14 12.3 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair Aminotran_1_2 PF00155.16 ETO08371.1 - 1.1e-55 189.0 0.0 1.4e-55 188.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II GAF_3 PF13492.1 ETO08371.1 - 0.14 12.2 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 GAF domain Actin PF00022.14 ETO08373.1 - 1.7e-53 181.4 0.0 2.1e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Actin ESSS PF10183.4 ETO08373.1 - 0.029 14.7 0.0 0.09 13.1 0.0 1.7 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Reo_sigmaC PF04582.7 ETO08374.1 - 0.0097 15.1 4.8 0.016 14.4 2.1 1.8 1 1 1 2 2 2 1 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 ETO08374.1 - 0.31 10.7 44.2 0.92 9.2 3.6 3.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Phage_GP20 PF06810.6 ETO08374.1 - 0.39 10.1 42.3 0.37 10.2 8.2 3.2 1 1 2 3 3 3 0 Phage minor structural protein GP20 HOOK PF05622.7 ETO08374.1 - 1 7.0 42.5 0.17 9.6 10.9 2.1 1 1 1 2 2 2 0 HOOK protein TraV PF09676.5 ETO08375.1 - 0.012 16.2 0.0 0.018 15.7 0.0 1.2 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) TRAP_alpha PF03896.11 ETO08375.1 - 0.097 11.6 2.6 0.13 11.2 1.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4312 PF14189.1 ETO08376.1 - 0.014 15.1 0.1 0.033 14.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4312) Raftlin PF15250.1 ETO08376.1 - 0.031 12.8 13.6 0.037 12.5 9.4 1.0 1 0 0 1 1 1 0 Raftlin DUF3449 PF11931.3 ETO08376.1 - 0.14 11.6 16.0 0.17 11.3 11.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Vfa1 PF08432.5 ETO08376.1 - 0.26 11.3 18.5 0.31 11.0 12.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 U79_P34 PF03064.11 ETO08376.1 - 0.27 10.7 16.9 0.32 10.4 11.7 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 NPR3 PF03666.8 ETO08376.1 - 0.28 9.6 15.8 0.29 9.6 11.0 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pox_Ag35 PF03286.9 ETO08376.1 - 0.4 10.1 20.8 0.53 9.7 14.5 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Rtf2 PF04641.7 ETO08376.1 - 0.6 9.2 18.2 0.73 8.9 12.6 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger NARP1 PF12569.3 ETO08376.1 - 0.71 8.5 16.7 0.81 8.3 11.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF1675 PF07897.6 ETO08376.1 - 0.79 9.5 11.9 1.1 9.0 8.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Utp14 PF04615.8 ETO08376.1 - 0.81 7.7 26.8 0.87 7.6 18.6 1.0 1 0 0 1 1 1 0 Utp14 protein Caldesmon PF02029.10 ETO08376.1 - 0.89 7.8 21.9 1.1 7.5 15.2 1.2 1 0 0 1 1 1 0 Caldesmon CDC45 PF02724.9 ETO08376.1 - 1.1 7.2 16.7 1.1 7.1 11.6 1.0 1 0 0 1 1 1 0 CDC45-like protein GAGA_bind PF06217.7 ETO08376.1 - 1.1 9.1 16.7 1.2 8.9 11.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Gag_spuma PF03276.9 ETO08376.1 - 1.1 7.4 15.6 1.3 7.2 10.8 1.1 1 0 0 1 1 1 0 Spumavirus gag protein SAPS PF04499.10 ETO08376.1 - 1.4 7.5 16.0 1.5 7.3 11.1 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF3595 PF12166.3 ETO08376.1 - 2.1 7.0 8.3 2.4 6.8 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) UPF0565 PF10561.4 ETO08376.1 - 2.2 7.0 15.7 2.8 6.7 10.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 ELL PF10390.4 ETO08376.1 - 2.5 7.2 18.2 2.9 7.0 12.6 1.1 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL BTV_NS2 PF04514.7 ETO08376.1 - 2.5 6.9 17.8 2.7 6.7 12.3 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Paramyxo_ncap PF00973.14 ETO08376.1 - 2.6 6.6 13.6 2.9 6.4 9.4 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF3807 PF12720.2 ETO08376.1 - 3 7.9 21.4 3.7 7.6 14.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) POP1 PF06978.6 ETO08376.1 - 3 7.4 14.6 4 7.0 10.1 1.2 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 Daxx PF03344.10 ETO08376.1 - 5.9 5.2 20.4 6.8 5.0 14.2 1.0 1 0 0 1 1 1 0 Daxx Family FAM60A PF15396.1 ETO08376.1 - 6.3 6.4 13.8 7.3 6.2 9.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A F-protein PF00469.15 ETO08376.1 - 6.9 5.9 10.3 7.8 5.8 7.1 1.2 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef DUF2370 PF10176.4 ETO08376.1 - 8 5.7 9.2 9.7 5.4 6.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Ago_hook PF10427.4 ETO08378.1 - 0.056 13.5 0.7 0.072 13.1 0.5 1.1 1 0 0 1 1 1 0 Argonaute hook Pkinase PF00069.20 ETO08379.1 - 0.0085 15.2 0.0 0.014 14.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain DUF2379 PF09543.5 ETO08380.1 - 0.02 14.8 0.1 0.038 13.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) HSBP1 PF06825.7 ETO08380.1 - 0.032 13.7 1.2 0.082 12.4 0.8 1.7 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Dimer_Tnp_hAT PF05699.9 ETO08380.1 - 0.38 10.4 2.5 0.59 9.7 0.1 2.5 3 0 0 3 3 3 0 hAT family C-terminal dimerisation region FliS PF02561.9 ETO08381.1 - 0.0015 18.3 0.3 0.0025 17.6 0.2 1.3 1 0 0 1 1 1 1 Flagellar protein FliS RNA_pol_Rpb5_C PF01191.14 ETO08381.1 - 0.062 12.8 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain zf-RING_2 PF13639.1 ETO08384.1 - 1.1e-08 34.7 9.6 1.1e-08 34.7 6.6 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO08384.1 - 2.5e-06 27.4 10.2 2.5e-06 27.4 7.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO08384.1 - 4.1e-06 26.3 7.0 4.1e-06 26.3 4.8 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 ETO08384.1 - 6.9e-05 22.4 5.9 6.9e-05 22.4 4.1 2.5 3 0 0 3 3 2 1 PHD-finger zf-rbx1 PF12678.2 ETO08384.1 - 0.00052 20.0 8.8 0.00052 20.0 6.1 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 ETO08384.1 - 0.0011 18.6 9.1 0.002 17.8 5.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 ETO08384.1 - 0.0039 17.0 5.6 0.0039 17.0 3.9 2.4 1 1 1 2 2 1 1 zinc finger of C3HC4-type, RING Nab1 PF04902.7 ETO08384.1 - 0.038 13.5 0.2 0.25 10.7 0.0 2.2 3 0 0 3 3 3 0 Conserved region in Nab1 zf-Apc11 PF12861.2 ETO08384.1 - 0.079 12.8 10.1 0.039 13.8 4.8 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.15 ETO08384.1 - 0.41 10.2 9.4 0.89 9.1 6.5 1.6 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger DZR PF12773.2 ETO08384.1 - 0.82 9.5 9.9 4.3 7.2 1.3 2.3 2 0 0 2 2 2 0 Double zinc ribbon zf-Nse PF11789.3 ETO08384.1 - 0.93 9.0 5.1 2.3 7.8 3.6 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-Di19 PF05605.7 ETO08384.1 - 4.1 7.6 11.7 2 8.5 4.7 2.6 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_UBOX PF13445.1 ETO08384.1 - 4.3 7.1 13.6 0.45 10.2 2.4 2.7 2 1 0 2 2 2 0 RING-type zinc-finger zf-HC5HC2H PF13771.1 ETO08384.1 - 6.7 6.9 13.3 0.28 11.3 3.7 2.6 2 1 1 3 3 3 0 PHD-like zinc-binding domain EF-hand_7 PF13499.1 ETO08385.1 - 1.4e-12 47.5 1.9 9.2e-06 25.7 0.3 3.3 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 ETO08385.1 - 1.6e-12 45.7 6.8 7.4e-06 24.8 0.1 4.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 ETO08385.1 - 2.6e-12 45.5 3.0 0.0004 20.0 0.1 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 ETO08385.1 - 2.2e-06 27.1 6.8 0.0041 16.6 0.0 4.1 3 2 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 ETO08385.1 - 8.5e-06 24.8 0.5 0.018 14.3 0.0 3.9 4 0 0 4 4 4 1 EF hand EF-hand_4 PF12763.2 ETO08385.1 - 0.0014 18.3 1.5 0.3 10.8 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 ETO08385.1 - 0.0014 18.4 0.1 0.0056 16.5 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain AdoHcyase_NAD PF00670.16 ETO08386.1 - 2.2e-83 277.9 4.7 2.8e-83 277.6 3.2 1.1 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AdoHcyase PF05221.12 ETO08386.1 - 3.8e-50 170.3 0.0 4.3e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase 2-Hacid_dh_C PF02826.14 ETO08386.1 - 1.7e-08 33.8 0.2 2.7e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 ETO08386.1 - 7.2e-06 25.4 0.4 1.1e-05 24.8 0.3 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 ETO08386.1 - 5.3e-05 23.1 1.0 0.00044 20.2 0.7 2.3 1 1 0 1 1 1 1 TrkA-N domain THF_DHG_CYH_C PF02882.14 ETO08386.1 - 5.6e-05 22.2 3.8 0.00045 19.3 2.7 2.1 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.1 ETO08386.1 - 0.0018 18.4 0.4 0.0035 17.5 0.3 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 ETO08386.1 - 0.0029 17.6 0.7 0.0068 16.5 0.5 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.16 ETO08386.1 - 0.005 16.4 0.7 0.01 15.4 0.2 1.6 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 3HCDH_N PF02737.13 ETO08386.1 - 0.014 15.1 0.9 0.034 13.7 0.2 1.8 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Malic_M PF03949.10 ETO08386.1 - 1.8 8.0 4.6 14 5.1 0.1 2.2 1 1 1 2 2 2 0 Malic enzyme, NAD binding domain AdoHcyase PF05221.12 ETO08387.1 - 3.2e-55 186.9 0.1 3.5e-55 186.8 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase Shisa PF13908.1 ETO08388.1 - 0.0016 18.6 0.4 0.0016 18.6 0.3 2.3 3 0 0 3 3 3 1 Wnt and FGF inhibitory regulator OppC_N PF12911.2 ETO08388.1 - 0.015 14.6 0.0 0.039 13.3 0.0 1.7 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C zf-LITAF-like PF10601.4 ETO08388.1 - 0.068 13.0 0.3 0.068 13.0 0.2 2.3 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain DUF2981 PF11200.3 ETO08388.1 - 7.4 5.5 12.4 9.9 5.1 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) DicB PF05358.6 ETO08391.1 - 0.12 11.9 0.2 0.21 11.0 0.1 1.4 1 0 0 1 1 1 0 DicB protein WD40 PF00400.27 ETO08394.1 - 1.2e-27 94.6 14.2 6.2e-11 41.7 2.3 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO08394.1 - 0.00082 18.2 0.9 2.1 6.9 0.0 3.5 3 1 1 4 4 4 3 Nup133 N terminal like Bap31 PF05529.7 ETO08394.1 - 9.2 5.6 6.8 16 4.8 4.7 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like YtxC PF08812.6 ETO08395.1 - 0.0082 15.6 0.7 0.011 15.2 0.5 1.2 1 0 0 1 1 1 1 YtxC-like family TPR_6 PF13174.1 ETO08395.1 - 0.11 12.9 0.0 0.41 11.2 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat VWA_2 PF13519.1 ETO08396.1 - 9.8e-11 42.0 0.0 1.9e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain SecA_DEAD PF07517.9 ETO08396.1 - 2.9e-09 36.5 4.5 1.6e-08 34.1 0.0 3.5 3 0 0 3 3 3 1 SecA DEAD-like domain NAAA-beta PF15508.1 ETO08396.1 - 0.012 15.9 0.9 0.22 11.8 0.1 3.8 3 0 0 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Helicase_C PF00271.26 ETO08396.1 - 0.015 15.1 0.0 0.15 11.8 0.0 2.6 2 0 0 2 2 2 0 Helicase conserved C-terminal domain Dynamin_N PF00350.18 ETO08398.1 - 0.0084 15.9 0.1 0.026 14.3 0.0 1.8 1 0 0 1 1 1 1 Dynamin family FliD_C PF07195.7 ETO08399.1 - 0.13 11.5 8.2 0.25 10.5 4.1 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus CENP-Q PF13094.1 ETO08399.1 - 0.13 12.2 6.6 0.069 13.1 0.5 2.3 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Ribosomal_S30AE PF02482.14 ETO08399.1 - 0.19 12.1 2.6 0.26 11.7 0.8 1.9 2 0 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein AAA_27 PF13514.1 ETO08399.1 - 0.46 8.1 6.3 0.6 7.7 4.4 1.1 1 0 0 1 1 1 0 AAA domain BTV_NS2 PF04514.7 ETO08399.1 - 0.6 8.9 9.5 1.8 7.3 6.6 1.6 1 1 0 1 1 1 0 Bluetongue virus non-structural protein NS2 YlqD PF11068.3 ETO08399.1 - 0.94 9.5 11.4 0.89 9.6 5.7 2.4 1 1 1 2 2 2 0 YlqD protein Sipho_Gp157 PF05565.6 ETO08399.1 - 1.4 8.5 12.9 0.078 12.5 4.2 2.3 2 1 1 3 3 3 0 Siphovirus Gp157 DUF342 PF03961.8 ETO08399.1 - 1.9 6.7 13.6 2.2 6.6 9.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Dict-STAT-coil PF09267.5 ETO08399.1 - 3 8.1 7.7 1.6 9.0 2.9 2.1 2 0 0 2 2 2 0 Dictyostelium STAT, coiled coil bZIP_1 PF00170.16 ETO08399.1 - 3.1 7.8 14.8 3 7.8 1.0 3.0 3 0 0 3 3 3 0 bZIP transcription factor SEA PF01390.15 ETO08399.1 - 3.2 7.4 5.6 2.8 7.6 0.0 3.3 4 0 0 4 4 4 0 SEA domain Atg14 PF10186.4 ETO08399.1 - 3.3 6.5 10.0 5.8 5.7 6.9 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TPR_MLP1_2 PF07926.7 ETO08399.1 - 3.5 7.3 15.9 2.1 8.0 3.0 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein E2_bind PF08825.5 ETO08399.1 - 4.9 6.9 7.2 1.8 8.3 0.2 2.9 2 1 1 3 3 3 0 E2 binding domain MreB_Mbl PF06723.8 ETO08400.1 - 0.083 11.4 0.0 1 7.8 0.0 2.0 2 0 0 2 2 2 0 MreB/Mbl protein DUF3682 PF12446.3 ETO08401.1 - 3.6 7.8 10.8 5.2 7.3 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Kinesin PF00225.18 ETO08402.1 - 4e-12 45.4 0.3 5.1e-12 45.1 0.2 1.1 1 0 0 1 1 1 1 Kinesin motor domain PG_binding_4 PF12229.3 ETO08402.1 - 0.035 14.3 0.1 12 6.1 0.0 2.3 2 0 0 2 2 2 0 Putative peptidoglycan binding domain Synaptobrevin PF00957.16 ETO08404.1 - 1.8e-06 27.4 3.3 1.8e-06 27.4 2.3 2.8 2 1 0 2 2 2 1 Synaptobrevin Z1 PF10593.4 ETO08404.1 - 0.014 14.5 0.4 0.029 13.6 0.3 1.5 1 0 0 1 1 1 0 Z1 domain Longin PF13774.1 ETO08404.1 - 0.14 11.7 2.5 0.21 11.1 0.3 2.5 2 1 0 2 2 2 0 Regulated-SNARE-like domain WD40 PF00400.27 ETO08405.1 - 0.00081 19.1 1.3 0.39 10.6 0.2 2.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Snf7 PF03357.16 ETO08406.1 - 0.066 12.5 18.0 0.51 9.7 1.0 2.4 1 1 1 2 2 2 0 Snf7 HSBP1 PF06825.7 ETO08406.1 - 0.14 11.7 0.2 0.14 11.7 0.1 2.5 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Strabismus PF06638.6 ETO08408.1 - 0.1 10.8 1.1 0.14 10.4 0.8 1.2 1 0 0 1 1 1 0 Strabismus protein DUF2045 PF09741.4 ETO08410.1 - 0.046 12.8 0.0 0.061 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2045) Kelch_6 PF13964.1 ETO08411.1 - 3.9e-08 33.1 8.7 0.0036 17.4 0.1 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO08411.1 - 8.9e-05 21.9 14.5 0.046 13.2 1.2 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO08411.1 - 0.0045 16.7 4.6 0.077 12.7 0.2 4.1 4 0 0 4 4 4 1 Galactose oxidase, central domain DUF267 PF03268.9 ETO08411.1 - 0.0066 15.3 0.3 0.015 14.1 0.0 1.7 2 0 0 2 2 2 1 Caenorhabditis protein of unknown function, DUF267 SEO_C PF14577.1 ETO08411.1 - 0.033 13.5 0.5 0.033 13.5 0.3 1.8 2 0 0 2 2 2 0 Sieve element occlusion C-terminus Kelch_5 PF13854.1 ETO08411.1 - 0.069 13.1 5.8 1.8 8.6 0.0 3.5 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.10 ETO08411.1 - 0.16 11.7 0.1 0.16 11.7 0.0 3.3 4 0 0 4 4 4 0 Kelch motif WD40 PF00400.27 ETO08412.1 - 9.1e-16 57.0 0.0 4e-12 45.5 0.0 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF3601 PF12208.3 ETO08412.1 - 0.012 15.5 0.0 0.3 11.0 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3601) WD40 PF00400.27 ETO08413.1 - 3.9e-21 74.0 4.6 3.8e-09 36.0 0.1 3.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO08413.1 - 6.4e-06 24.5 0.1 0.0089 14.2 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 MLANA PF14991.1 ETO08414.1 - 0.18 11.8 1.0 0.21 11.6 0.7 1.3 1 0 0 1 1 1 0 Protein melan-A RVT_1 PF00078.22 ETO08416.1 - 0.00013 21.3 0.2 0.00038 19.8 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DnaG_DnaB_bind PF08278.6 ETO08416.1 - 0.062 13.5 0.1 0.24 11.6 0.0 2.0 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding Exo_endo_phos_2 PF14529.1 ETO08417.1 - 6.3e-20 70.9 1.4 6.3e-20 70.9 0.9 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase DUF2057 PF09829.4 ETO08417.1 - 0.018 14.7 0.3 0.033 13.8 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) DUF4618 PF15397.1 ETO08417.1 - 0.45 9.8 5.1 0.086 12.1 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) YscO PF07321.7 ETO08417.1 - 0.66 9.7 3.6 0.51 10.1 0.5 2.0 2 0 0 2 2 2 0 Type III secretion protein YscO DUF3870 PF12986.2 ETO08418.1 - 0.23 11.7 3.7 0.12 12.6 0.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3870) WD40 PF00400.27 ETO08419.1 - 3.5e-12 45.7 6.3 5.6e-11 41.8 1.6 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO08419.1 - 1.9e-05 23.0 0.4 2.2e-05 22.7 0.3 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO08419.1 - 0.0058 16.0 0.8 0.0077 15.5 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4221) EF-hand_1 PF00036.27 ETO08423.1 - 0.0011 18.1 0.0 0.0023 17.1 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 ETO08423.1 - 0.0047 16.7 0.0 0.013 15.3 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 ETO08423.1 - 0.0081 15.4 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 ETO08423.1 - 0.009 16.1 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair DUF964 PF06133.6 ETO08423.1 - 0.11 12.4 3.0 0.17 11.8 2.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF964) TPR_12 PF13424.1 ETO08424.1 - 1.8e-173 562.9 38.2 2.5e-30 104.2 0.2 6.2 1 1 7 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.1 ETO08424.1 - 5e-69 226.4 0.0 8.6e-10 38.2 0.0 8.2 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_11 PF13414.1 ETO08424.1 - 4.1e-67 221.7 46.5 3.6e-19 68.1 1.5 5.6 2 2 3 6 6 6 6 TPR repeat TPR_1 PF00515.23 ETO08424.1 - 8.7e-62 202.3 53.9 6.7e-11 41.3 0.6 9.3 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_7 PF13176.1 ETO08424.1 - 1.3e-59 193.2 18.0 1.1e-08 34.1 0.0 8.5 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_2 PF07719.12 ETO08424.1 - 1.2e-54 177.8 36.4 3.7e-08 32.6 0.1 9.2 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_8 PF13181.1 ETO08424.1 - 1.2e-47 156.0 64.4 1e-08 34.3 1.8 8.4 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_17 PF13431.1 ETO08424.1 - 5.5e-39 129.1 13.0 9.6e-05 22.2 0.1 9.2 8 1 0 8 8 8 7 Tetratricopeptide repeat TPR_16 PF13432.1 ETO08424.1 - 1.6e-28 98.7 0.2 5.6e-06 26.8 0.0 7.4 1 1 7 8 8 8 7 Tetratricopeptide repeat TPR_14 PF13428.1 ETO08424.1 - 3.5e-23 79.9 0.0 0.043 14.4 0.0 8.9 5 2 4 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.1 ETO08424.1 - 4.8e-19 67.4 18.5 0.024 15.0 0.3 8.8 9 0 0 9 9 8 5 Tetratricopeptide repeat PPR PF01535.15 ETO08424.1 - 1.4e-15 56.0 20.9 0.055 13.4 0.1 8.5 9 0 0 9 9 8 4 PPR repeat Apc3 PF12895.2 ETO08424.1 - 3.6e-14 52.6 26.9 2.8e-05 24.1 2.2 5.6 1 1 7 8 8 8 8 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO08424.1 - 4.9e-14 52.4 8.9 0.0041 17.4 0.1 6.4 3 2 4 7 7 7 6 Tetratricopeptide repeat TPR_3 PF07720.7 ETO08424.1 - 1.5e-10 40.6 45.5 0.31 10.9 0.2 9.0 9 0 0 9 9 9 6 Tetratricopeptide repeat MIT PF04212.13 ETO08424.1 - 2.3e-10 40.1 37.2 0.013 15.3 0.9 7.7 8 0 0 8 8 7 4 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.4 ETO08424.1 - 2.4e-07 29.8 10.4 0.43 9.8 0.0 6.3 7 0 0 7 7 6 2 SHNi-TPR Ten1_2 PF15490.1 ETO08424.1 - 3.1e-07 30.0 0.0 4.2 6.9 0.0 6.2 1 1 7 8 8 8 1 Telomere-capping, CST complex subunit Pep3_Vps18 PF05131.9 ETO08424.1 - 5.8e-07 29.0 6.4 8.8 5.7 0.0 7.0 7 0 0 7 7 7 0 Pep3/Vps18/deep orange family Sel1 PF08238.7 ETO08424.1 - 1e-05 25.9 27.6 1.8 9.2 0.0 8.3 9 0 0 9 9 8 2 Sel1 repeat TPR_21 PF09976.4 ETO08424.1 - 3.8e-05 23.6 10.0 0.054 13.4 0.0 5.4 4 3 0 4 4 4 1 Tetratricopeptide repeat DUF627 PF04781.7 ETO08424.1 - 0.00014 21.4 21.6 0.72 9.4 0.0 7.1 3 1 5 8 8 8 2 Protein of unknown function (DUF627) PPR_2 PF13041.1 ETO08424.1 - 0.00019 21.3 12.6 6.1 6.8 0.0 7.2 9 0 0 9 9 8 0 PPR repeat family DUF3568 PF12092.3 ETO08424.1 - 0.00029 20.5 0.1 10 5.8 0.0 4.7 2 2 2 5 5 5 0 Protein of unknown function (DUF3568) DUF3856 PF12968.2 ETO08424.1 - 0.00057 19.7 6.1 9.6 6.0 0.0 4.8 1 1 3 5 5 4 0 Domain of Unknown Function (DUF3856) Musclin PF11037.3 ETO08424.1 - 0.0012 18.4 0.0 66 3.1 0.0 5.5 5 1 1 6 6 6 0 Insulin-resistance promoting peptide in skeletal muscle RPN7 PF10602.4 ETO08424.1 - 0.002 17.5 23.2 0.96 8.7 0.2 7.0 2 2 4 7 7 7 1 26S proteasome subunit RPN7 TPR_5 PF12688.2 ETO08424.1 - 0.0047 16.9 5.7 19 5.2 0.0 5.6 4 3 3 7 7 6 0 Tetratrico peptide repeat TPR_9 PF13371.1 ETO08424.1 - 0.0091 15.8 0.0 1.3 8.9 0.0 3.5 2 2 1 4 4 3 1 Tetratricopeptide repeat DUF2225 PF09986.4 ETO08424.1 - 0.011 15.2 25.6 0.61 9.4 0.4 5.1 1 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) Mob_Pre PF01076.14 ETO08424.1 - 0.068 12.7 13.3 2.3 7.8 0.0 4.8 2 1 3 5 5 5 0 Plasmid recombination enzyme RPA_interact_M PF14767.1 ETO08424.1 - 0.16 12.7 1.6 85 4.0 0.0 4.6 2 2 2 4 4 4 0 Replication protein A interacting middle Sec5 PF15469.1 ETO08424.1 - 0.19 11.4 15.9 3.1 7.5 0.4 4.9 2 1 0 3 3 3 0 Exocyst complex component Sec5 FATC PF02260.15 ETO08424.1 - 0.61 9.5 9.8 41 3.7 0.1 4.8 5 0 0 5 5 5 0 FATC domain UAE_UbL PF14732.1 ETO08424.1 - 3.4 7.8 5.0 6.8 6.8 0.0 3.2 2 2 3 5 5 4 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Phage_C PF12025.3 ETO08425.1 - 0.13 12.2 1.1 0.5 10.3 0.0 2.3 2 0 0 2 2 2 0 Phage protein C WD40 PF00400.27 ETO08426.1 - 2.2e-05 24.1 0.7 4.3e-05 23.2 0.5 1.5 1 0 0 1 1 1 1 WD domain, G-beta repeat zf-TRAF PF02176.13 ETO08426.1 - 2.8e-05 24.4 0.9 2.8e-05 24.4 0.6 2.5 2 1 1 3 3 3 1 TRAF-type zinc finger M11L PF11099.3 ETO08426.1 - 0.0089 15.7 0.1 0.049 13.3 0.0 2.1 2 0 0 2 2 2 1 Apoptosis regulator M11L like Nup160 PF11715.3 ETO08426.1 - 0.059 11.4 0.0 0.077 11.1 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DUF2672 PF10878.3 ETO08426.1 - 0.3 10.8 3.1 19 5.0 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2672) zf-RING_2 PF13639.1 ETO08426.1 - 1.4 8.7 5.8 0.46 10.3 0.3 2.8 2 2 0 2 2 2 0 Ring finger domain WD40 PF00400.27 ETO08427.1 - 4.8e-14 51.6 2.0 2.9e-11 42.7 0.1 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO08427.1 - 0.51 9.0 5.8 0.65 8.6 3.6 1.6 1 1 0 1 1 1 0 Nup133 N terminal like WD40 PF00400.27 ETO08429.1 - 8.7e-25 85.6 9.3 6.2e-08 32.2 0.1 4.0 3 1 0 3 3 3 3 WD domain, G-beta repeat DUF972 PF06156.8 ETO08430.1 - 0.00031 21.0 2.7 0.0004 20.6 1.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF972) MAGSP PF03082.9 ETO08430.1 - 0.00059 19.3 2.7 0.00065 19.1 1.9 1.2 1 0 0 1 1 1 1 Male accessory gland secretory protein bZIP_1 PF00170.16 ETO08430.1 - 0.0016 18.3 1.5 0.0016 18.3 1.0 2.2 3 0 0 3 3 3 1 bZIP transcription factor DivIC PF04977.10 ETO08430.1 - 0.0069 15.8 1.2 0.0069 15.8 0.9 1.7 2 0 0 2 2 2 1 Septum formation initiator TSC22 PF01166.13 ETO08430.1 - 0.012 15.6 1.7 2.9 7.9 0.2 2.5 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF465 PF04325.8 ETO08430.1 - 0.043 13.5 0.4 0.043 13.5 0.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF465) DUF2968 PF11180.3 ETO08430.1 - 0.055 12.8 0.3 0.073 12.4 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) Ax_dynein_light PF10211.4 ETO08430.1 - 0.094 12.5 2.8 0.12 12.1 1.9 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain DAG1 PF05454.6 ETO08430.1 - 0.1 11.7 0.8 0.12 11.5 0.6 1.0 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) AATF-Che1 PF13339.1 ETO08430.1 - 0.23 11.6 4.5 0.3 11.2 3.1 1.4 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor FlaC_arch PF05377.6 ETO08430.1 - 0.98 9.3 5.1 1.3 9.0 2.9 1.8 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF2205 PF10224.4 ETO08430.1 - 1.7 8.3 6.8 0.081 12.5 0.9 1.7 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) FlxA PF14282.1 ETO08430.1 - 3.4 7.6 11.8 4.2 7.3 6.4 2.2 1 1 1 2 2 2 0 FlxA-like protein DUF904 PF06005.7 ETO08430.1 - 3.7 7.9 7.4 8.9 6.6 5.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Ank_5 PF13857.1 ETO08431.1 - 3.1e-05 24.0 0.0 5.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO08431.1 - 0.00051 20.0 0.6 0.014 15.5 0.1 3.0 2 1 1 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 ETO08431.1 - 0.0011 19.4 0.1 0.0038 17.7 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO08431.1 - 0.009 16.3 0.0 0.013 15.7 0.0 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) DUF4064 PF13273.1 ETO08431.1 - 0.031 14.3 0.9 0.82 9.8 0.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) Ank PF00023.25 ETO08431.1 - 0.041 13.7 0.2 0.14 11.9 0.1 1.9 2 0 0 2 2 2 0 Ankyrin repeat Dicty_REP PF05086.7 ETO08431.1 - 0.048 11.4 1.3 0.066 10.9 0.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TMEM220 PF15071.1 ETO08431.1 - 0.064 13.7 0.0 8.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Transmembrane family 220, helix SH3_1 PF00018.23 ETO08432.1 - 9.5e-05 21.7 0.0 0.00023 20.4 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 ETO08432.1 - 0.03 13.8 0.0 0.075 12.6 0.0 1.7 1 1 0 1 1 1 0 Variant SH3 domain HNH_5 PF14279.1 ETO08432.1 - 0.072 13.1 0.7 0.15 12.1 0.5 1.5 1 0 0 1 1 1 0 HNH endonuclease RasGEF PF00617.14 ETO08433.1 - 1.6e-54 184.5 1.5 3.2e-54 183.5 1.1 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 ETO08433.1 - 0.00056 19.9 0.7 0.0019 18.2 0.5 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif PUB PF09409.5 ETO08434.1 - 1e-09 37.9 0.0 2.8e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 PUB domain RasGEF_N PF00618.15 ETO08434.1 - 0.15 12.1 0.1 0.15 12.1 0.1 2.1 2 1 0 2 2 2 0 RasGEF N-terminal motif TRAP_alpha PF03896.11 ETO08434.1 - 0.33 9.8 7.2 0.49 9.3 5.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Osteopontin PF00865.13 ETO08434.1 - 0.34 10.1 14.7 0.56 9.3 10.2 1.3 1 0 0 1 1 1 0 Osteopontin Daxx PF03344.10 ETO08434.1 - 0.79 8.1 19.3 0.02 13.3 7.2 1.9 2 0 0 2 2 2 0 Daxx Family DUF4484 PF14831.1 ETO08434.1 - 0.96 9.5 6.8 0.39 10.8 2.4 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4484) Sec62 PF03839.11 ETO08434.1 - 1.2 8.4 7.3 2.6 7.3 5.1 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 DUF912 PF06024.7 ETO08434.1 - 1.9 8.5 5.8 6.5 6.8 4.0 2.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CENP-T PF15511.1 ETO08434.1 - 4.1 6.5 11.7 0.15 11.2 2.3 2.0 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T WD40 PF00400.27 ETO08437.1 - 5.2e-77 251.2 18.9 2.6e-13 49.2 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO08437.1 - 2.6e-10 39.0 6.5 0.069 11.2 0.0 4.7 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO08437.1 - 0.00034 19.0 0.8 0.0057 14.9 0.1 2.6 1 1 2 3 3 3 1 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO08437.1 - 0.00054 19.1 1.1 5 6.1 0.0 4.1 1 1 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 ETO08437.1 - 0.001 18.6 0.1 0.025 14.0 0.1 2.6 1 1 0 1 1 1 1 PQQ-like domain Kelch_6 PF13964.1 ETO08437.1 - 0.0047 17.0 0.2 0.0047 17.0 0.2 3.9 6 0 0 6 6 5 1 Kelch motif PD40 PF07676.7 ETO08437.1 - 0.0071 15.9 9.1 7.7 6.3 0.0 5.5 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Kelch_2 PF07646.10 ETO08437.1 - 0.009 15.7 0.7 0.16 11.8 0.2 3.1 2 0 0 2 2 2 1 Kelch motif DPPIV_N PF00930.16 ETO08437.1 - 0.0091 14.6 0.1 3 6.3 0.0 3.6 2 2 3 5 5 5 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Kelch_5 PF13854.1 ETO08437.1 - 0.01 15.8 0.8 0.022 14.7 0.6 1.6 1 0 0 1 1 1 1 Kelch motif DUF1258 PF06869.7 ETO08437.1 - 0.013 14.5 1.7 0.25 10.3 0.1 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF1258) Kelch_4 PF13418.1 ETO08437.1 - 0.042 13.6 2.4 0.2 11.4 0.1 3.4 4 1 1 5 5 5 0 Galactose oxidase, central domain Ricin_B_lectin PF00652.17 ETO08437.1 - 0.085 12.8 1.6 2.1 8.3 0.3 2.8 2 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain Kelch_1 PF01344.20 ETO08437.1 - 0.4 10.2 4.7 0.12 11.9 0.4 2.3 2 0 0 2 2 2 0 Kelch motif Proteasome_A_N PF10584.4 ETO08437.1 - 0.91 8.9 10.4 3.7 6.9 0.0 4.3 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature zf-RING_2 PF13639.1 ETO08438.1 - 7.2e-15 54.5 10.2 2.2e-14 53.0 7.1 1.9 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 ETO08438.1 - 7.6e-08 32.3 7.6 7.6e-08 32.3 5.2 2.4 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 ETO08438.1 - 2e-07 30.9 11.2 5e-07 29.6 7.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO08438.1 - 5.8e-07 29.0 11.1 1.9e-06 27.4 7.7 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO08438.1 - 7.3e-07 28.7 8.6 1.6e-06 27.6 5.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO08438.1 - 8.5e-06 25.4 10.8 2.3e-05 24.0 7.5 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 ETO08438.1 - 5.5e-05 22.9 4.9 0.00015 21.5 3.4 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 ETO08438.1 - 0.0079 15.8 5.7 0.027 14.1 3.8 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.3 ETO08438.1 - 1.6 8.3 10.0 0.84 9.1 4.8 2.2 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.2 ETO08438.1 - 5.3 7.1 15.6 1.7 8.7 8.3 2.2 2 0 0 2 2 2 0 RING-variant domain DUF1049 PF06305.6 ETO08439.1 - 0.0066 15.9 0.3 0.0097 15.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1049) DUF1504 PF07399.6 ETO08439.1 - 0.074 11.6 0.0 0.086 11.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1504) DUF4229 PF14012.1 ETO08439.1 - 0.079 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) MadL PF03817.8 ETO08439.1 - 0.086 12.7 4.3 0.11 12.3 3.0 1.1 1 0 0 1 1 1 0 Malonate transporter MadL subunit DUF3951 PF13131.1 ETO08439.1 - 0.13 12.0 1.9 0.21 11.4 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) PX PF00787.19 ETO08440.1 - 8.2e-08 32.0 0.6 1.3e-07 31.3 0.4 1.3 1 0 0 1 1 1 1 PX domain Gpi16 PF04113.9 ETO08441.1 - 0.00011 20.3 0.3 0.0002 19.5 0.1 1.4 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component DAGK_cat PF00781.19 ETO08441.1 - 0.0076 15.6 0.0 0.016 14.5 0.0 1.6 1 1 1 2 2 2 1 Diacylglycerol kinase catalytic domain YtxC PF08812.6 ETO08441.1 - 0.1 12.0 3.1 3.3 7.1 0.0 2.1 2 0 0 2 2 2 0 YtxC-like family Phyto_Pns9_10 PF05878.6 ETO08441.1 - 0.15 11.0 1.2 0.16 10.9 0.1 1.5 2 0 0 2 2 2 0 Phytoreovirus nonstructural protein Pns9/Pns10 FA_desaturase PF00487.19 ETO08442.1 - 1.1 8.6 10.2 0.29 10.5 0.3 2.2 1 1 1 2 2 2 0 Fatty acid desaturase UBX PF00789.15 ETO08443.1 - 6.8e-10 38.8 0.1 2.1e-09 37.2 0.1 1.9 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 ETO08443.1 - 3e-08 33.0 1.5 6.5e-08 31.9 1.1 1.5 1 0 0 1 1 1 1 UBA-like domain Glyco_hydro_45 PF02015.11 ETO08443.1 - 0.088 12.8 1.8 0.13 12.2 0.2 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 45 Ribonuclease_3 PF00636.21 ETO08445.1 - 0.051 14.0 1.4 2.9 8.3 0.3 2.3 2 0 0 2 2 2 0 Ribonuclease III domain Cnd1_N PF12922.2 ETO08445.1 - 0.082 12.5 2.8 0.056 13.0 0.7 1.6 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term WD40 PF00400.27 ETO08446.1 - 1.9e-46 154.3 20.0 2.1e-11 43.2 2.1 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO08446.1 - 4.7e-06 25.6 7.8 0.1 11.3 0.7 3.0 1 1 2 3 3 3 3 Nup133 N terminal like eIF2A PF08662.6 ETO08446.1 - 8.2e-06 25.6 0.4 0.0033 17.1 0.1 2.1 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO08446.1 - 8e-05 20.9 2.0 0.34 8.9 0.0 3.2 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 ETO08446.1 - 0.0011 17.9 1.4 0.086 11.6 0.1 2.3 1 1 2 3 3 3 2 Coatomer WD associated region Resistin PF06954.6 ETO08446.1 - 0.04 14.1 2.2 15 5.9 0.1 3.4 1 1 3 4 4 4 0 Resistin Mo25 PF08569.6 ETO08447.1 - 6.5e-64 216.0 29.2 1.4e-62 211.6 20.2 2.6 1 1 0 1 1 1 1 Mo25-like zf-RING_2 PF13639.1 ETO08449.1 - 4.8e-08 32.6 3.6 3e-06 26.9 0.6 2.7 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.2 ETO08449.1 - 3.7e-06 26.9 1.7 3.7e-06 26.9 1.2 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 ETO08449.1 - 0.0016 18.1 2.2 0.0026 17.5 0.6 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 ETO08449.1 - 0.003 17.5 4.8 0.014 15.3 0.8 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO08449.1 - 0.0068 16.1 5.4 0.019 14.6 1.5 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 ETO08449.1 - 0.013 15.1 4.4 0.33 10.6 0.5 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TP_methylase PF00590.15 ETO08450.1 - 8.8e-19 68.0 0.0 1.2e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Ribosomal_L5_C PF00673.16 ETO08450.1 - 1.4e-13 50.3 0.0 9.8e-13 47.6 0.0 2.3 2 0 0 2 2 2 1 ribosomal L5P family C-terminus WD40 PF00400.27 ETO08452.1 - 4.9e-43 143.5 28.4 1.5e-09 37.3 2.9 6.9 6 2 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO08452.1 - 7.1e-07 27.7 5.5 0.14 10.2 0.2 3.9 2 2 2 4 4 4 4 Nucleoporin Nup120/160 CRM1_C PF08767.6 ETO08453.1 - 1.1e-16 60.6 1.4 1.4e-16 60.2 1.0 1.1 1 0 0 1 1 1 1 CRM1 C terminal DUF4521 PF15021.1 ETO08453.1 - 0.081 12.4 0.1 0.13 11.7 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4521) BTV_NS2 PF04514.7 ETO08454.1 - 0.048 12.5 0.1 0.058 12.2 0.0 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Secretin_N_2 PF07655.8 ETO08454.1 - 1.1 9.6 10.9 2.3 8.6 7.5 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain Peptidase_S49_N PF08496.5 ETO08456.1 - 2.7 7.7 8.7 2.2 8.0 1.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Med8 PF10232.4 ETO08457.1 - 2.9e-05 23.6 5.5 5.6e-05 22.7 3.1 1.8 1 1 1 2 2 2 1 Mediator of RNA polymerase II transcription complex subunit 8 DUF2802 PF10975.3 ETO08457.1 - 2.5 7.9 6.8 1.6 8.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) YlbD_coat PF14071.1 ETO08457.1 - 5.3 7.1 8.1 7.2 6.6 1.9 2.1 1 1 0 2 2 2 0 Putative coat protein zf-RING_2 PF13639.1 ETO08458.1 - 5.8e-09 35.6 14.4 1.5e-08 34.3 10.0 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 ETO08458.1 - 6.4e-08 32.1 15.4 1.9e-07 30.6 10.7 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO08458.1 - 2.4e-07 30.6 15.3 2.4e-07 30.6 10.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO08458.1 - 7.3e-07 28.7 15.4 7.3e-07 28.7 10.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 ETO08458.1 - 2.9e-06 27.0 10.9 2.9e-06 27.0 7.6 2.2 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 ETO08458.1 - 7.9e-05 22.3 14.2 0.00023 20.7 9.9 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 ETO08458.1 - 0.00085 18.9 5.6 0.00085 18.9 3.9 2.7 1 1 1 2 2 2 1 RING-type zinc-finger RNA_pol_Rpb2_6 PF00562.23 ETO08458.1 - 0.0061 15.3 1.6 0.0074 15.0 1.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 CDC27 PF09507.5 ETO08458.1 - 0.058 12.6 22.3 0.7 9.0 14.2 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 FLO_LFY PF01698.11 ETO08458.1 - 0.25 10.1 12.9 0.4 9.4 9.0 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Neur_chan_memb PF02932.11 ETO08458.1 - 5.3 6.8 7.1 11 5.8 4.9 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region zf-Nse PF11789.3 ETO08458.1 - 5.5 6.5 12.7 6.3 6.4 5.8 2.6 2 1 1 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit mTERF PF02536.9 ETO08459.1 - 0.0014 17.2 0.3 0.0024 16.5 0.2 1.3 1 0 0 1 1 1 1 mTERF 2OG-FeII_Oxy_2 PF13532.1 ETO08460.1 - 2.6e-10 40.4 0.0 3.6e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SAM_1 PF00536.25 ETO08461.1 - 0.00047 20.2 0.4 0.004 17.2 0.1 2.4 2 1 0 2 2 2 1 SAM domain (Sterile alpha motif) DUF406 PF04175.7 ETO08461.1 - 0.023 15.1 0.0 0.16 12.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF406) Pkinase PF00069.20 ETO08462.1 - 7.2e-49 166.2 0.0 8.4e-49 166.0 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO08462.1 - 2.1e-21 76.1 0.0 3.1e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO08462.1 - 0.00025 20.2 0.0 0.00046 19.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETO08462.1 - 0.0011 17.9 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETO08462.1 - 0.015 15.0 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.27 ETO08463.1 - 1.9e-14 52.8 15.4 4e-07 29.6 0.2 4.9 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO08463.1 - 0.00021 19.5 0.1 0.21 9.7 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO08463.1 - 0.044 12.5 2.5 0.72 8.5 1.7 2.4 1 1 0 1 1 1 0 Nup133 N terminal like TetM_leader PF08076.6 ETO08463.1 - 0.12 11.9 0.9 0.34 10.4 0.6 1.8 1 0 0 1 1 1 0 Tetracycline resistance determinant leader peptide WD40 PF00400.27 ETO08465.1 - 3.7e-44 147.0 25.5 4e-11 42.3 0.5 5.7 5 1 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO08465.1 - 1.5e-10 39.8 10.8 0.00016 19.9 0.5 4.4 1 1 2 4 4 4 4 Nucleoporin Nup120/160 DUF4570 PF15134.1 ETO08465.1 - 0.26 11.1 5.2 0.49 10.2 3.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) CCDC144C PF14915.1 ETO08465.1 - 0.42 9.4 17.5 0.61 8.9 12.2 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region OmpH PF03938.9 ETO08465.1 - 1.9 8.3 15.3 1.4 8.8 9.8 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Tox-ODYAM1 PF15642.1 ETO08465.1 - 6.1 5.3 9.5 11 4.5 6.6 1.3 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus PALP PF00291.20 ETO08466.1 - 0.0022 17.2 0.0 0.0026 17.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AKNA PF12443.3 ETO08467.1 - 0.039 13.9 2.4 0.039 13.9 1.7 2.2 2 1 0 2 2 2 0 AT-hook-containing transcription factor HMG_CoA_synt_N PF01154.12 ETO08467.1 - 0.11 12.0 0.3 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF2521 PF10730.4 ETO08467.1 - 0.15 11.8 9.3 0.019 14.7 3.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2521) WD40 PF00400.27 ETO08468.1 - 4.8e-38 127.6 14.7 8.7e-12 44.4 0.1 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO08468.1 - 2.9e-10 38.9 1.3 0.00014 20.2 0.2 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO08468.1 - 0.0031 17.2 0.0 0.27 11.0 0.0 2.4 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Kelch_2 PF07646.10 ETO08468.1 - 0.038 13.7 0.6 0.34 10.7 0.1 2.7 2 0 0 2 2 2 0 Kelch motif Peptidase_C14 PF00656.17 ETO08469.1 - 8.3e-07 28.9 0.4 1.2e-06 28.4 0.3 1.2 1 0 0 1 1 1 1 Caspase domain alpha-hel2 PF14456.1 ETO08470.1 - 0.0027 16.5 7.6 0.0045 15.8 5.3 1.3 1 0 0 1 1 1 1 Alpha-helical domain 2 LAM_C PF12544.3 ETO08470.1 - 2.1 8.4 10.7 4.5 7.3 7.4 1.6 1 0 0 1 1 1 0 Lysine-2,3-aminomutase PRP38_assoc PF12871.2 ETO08470.1 - 8.7 6.9 14.9 16 6.1 10.3 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term AAA PF00004.24 ETO08471.1 - 0.0013 18.9 0.1 0.0024 18.0 0.1 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETO08471.1 - 0.014 15.1 0.0 0.052 13.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 ETO08471.1 - 0.12 12.6 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 ABC transporter Peptidase_M1 PF01433.15 ETO08472.1 - 1.5e-91 307.4 2.7 5.2e-91 305.6 1.9 1.7 1 1 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 ETO08472.1 - 1e-12 48.1 0.2 1.5e-12 47.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase MA superfamily WLM PF08325.5 ETO08472.1 - 0.047 13.5 0.0 0.073 12.9 0.0 1.2 1 0 0 1 1 1 0 WLM domain DUF1570 PF07607.6 ETO08472.1 - 0.3 11.0 1.6 1.4 8.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1570) Yippee-Mis18 PF03226.9 ETO08474.1 - 8.9e-11 41.6 0.7 2.2e-10 40.4 0.5 1.7 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TMF_DNA_bd PF12329.3 ETO08474.1 - 0.00013 21.7 16.2 0.00013 21.7 11.2 2.3 1 1 1 2 2 2 1 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 ETO08474.1 - 0.00042 19.4 12.9 0.0006 18.9 8.9 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 Filament PF00038.16 ETO08474.1 - 0.00085 18.8 10.8 0.0012 18.4 7.5 1.3 1 0 0 1 1 1 1 Intermediate filament protein Seryl_tRNA_N PF02403.17 ETO08474.1 - 0.0012 18.8 14.2 0.0019 18.1 9.8 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.6 ETO08474.1 - 0.0024 16.5 10.6 0.0036 16.0 7.3 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein GFA PF04828.9 ETO08474.1 - 0.0034 17.2 3.3 0.34 10.8 0.1 2.8 2 1 1 3 3 2 1 Glutathione-dependent formaldehyde-activating enzyme Baculo_PEP_C PF04513.7 ETO08474.1 - 0.0039 17.0 2.3 0.0062 16.3 1.6 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_I PF06008.9 ETO08474.1 - 0.0063 15.8 11.8 0.0084 15.4 8.2 1.2 1 0 0 1 1 1 1 Laminin Domain I GAS PF13851.1 ETO08474.1 - 0.0098 15.1 21.6 0.2 10.8 6.5 2.1 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Atg14 PF10186.4 ETO08474.1 - 0.01 14.8 8.0 0.017 14.1 5.5 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1943 PF09172.6 ETO08474.1 - 0.01 14.7 2.0 0.014 14.2 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) FlgN PF05130.7 ETO08474.1 - 0.013 15.7 7.2 0.02 15.1 5.0 1.3 1 0 0 1 1 1 0 FlgN protein LUC7 PF03194.10 ETO08474.1 - 0.013 15.0 10.8 0.02 14.4 7.5 1.3 1 0 0 1 1 1 0 LUC7 N_terminus IFT57 PF10498.4 ETO08474.1 - 0.014 14.1 11.5 0.017 13.8 8.0 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 IncA PF04156.9 ETO08474.1 - 0.016 14.8 15.0 0.076 12.6 4.2 1.9 1 1 1 2 2 2 0 IncA protein WEMBL PF05701.6 ETO08474.1 - 0.021 13.3 17.3 0.032 12.6 11.4 1.5 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Lebercilin PF15619.1 ETO08474.1 - 0.025 13.9 14.3 0.037 13.4 9.9 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Med4 PF10018.4 ETO08474.1 - 0.026 13.9 13.3 0.044 13.1 1.3 2.1 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Reo_sigmaC PF04582.7 ETO08474.1 - 0.027 13.6 0.7 0.042 13.0 0.5 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein zf-ribbon_3 PF13248.1 ETO08474.1 - 0.047 12.9 0.2 2.4 7.4 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain DivIC PF04977.10 ETO08474.1 - 0.052 13.0 14.9 0.81 9.2 1.8 2.6 1 1 1 2 2 2 0 Septum formation initiator LLC1 PF14945.1 ETO08474.1 - 0.055 13.7 3.4 0.11 12.8 2.4 1.6 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein SprT-like PF10263.4 ETO08474.1 - 0.062 12.9 0.4 0.25 10.9 0.3 1.9 1 1 0 1 1 1 0 SprT-like family V_ATPase_I PF01496.14 ETO08474.1 - 0.069 11.0 9.9 0.087 10.6 6.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HAUS-augmin3 PF14932.1 ETO08474.1 - 0.069 12.3 9.0 0.11 11.6 6.2 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF3584 PF12128.3 ETO08474.1 - 0.069 10.4 12.1 0.085 10.1 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) EzrA PF06160.7 ETO08474.1 - 0.073 11.2 13.5 0.36 8.9 9.5 1.7 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Fib_alpha PF08702.5 ETO08474.1 - 0.079 13.0 11.4 0.095 12.8 2.3 2.3 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family LIM PF00412.17 ETO08474.1 - 0.081 12.9 1.1 14 5.8 0.1 2.4 2 0 0 2 2 2 0 LIM domain zf-HYPF PF07503.7 ETO08474.1 - 0.084 12.3 1.8 3.3 7.1 0.0 2.4 2 0 0 2 2 2 0 HypF finger TIP120 PF08623.5 ETO08474.1 - 0.085 12.4 3.5 0.13 11.8 2.5 1.3 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) DUF4618 PF15397.1 ETO08474.1 - 0.087 12.1 15.5 0.42 9.8 10.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) AAA_13 PF13166.1 ETO08474.1 - 0.091 11.2 13.4 0.12 10.7 9.3 1.1 1 0 0 1 1 1 0 AAA domain Lzipper-MIP1 PF14389.1 ETO08474.1 - 0.095 12.8 10.0 0.54 10.4 6.9 2.0 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 zinc_ribbon_2 PF13240.1 ETO08474.1 - 0.096 12.1 3.3 4.6 6.8 0.0 3.0 3 0 0 3 3 2 0 zinc-ribbon domain TBPIP PF07106.8 ETO08474.1 - 0.098 12.2 19.9 0.16 11.5 7.4 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CENP-F_leu_zip PF10473.4 ETO08474.1 - 0.11 12.3 21.2 0.25 11.1 14.7 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Stn1 PF10451.4 ETO08474.1 - 0.13 11.0 4.2 0.2 10.4 2.9 1.2 1 0 0 1 1 1 0 Telomere regulation protein Stn1 CENP-Q PF13094.1 ETO08474.1 - 0.14 12.2 14.6 0.21 11.5 10.1 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF342 PF03961.8 ETO08474.1 - 0.14 10.5 12.3 0.2 10.0 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Laminin_II PF06009.7 ETO08474.1 - 0.16 11.7 12.1 0.24 11.1 8.4 1.2 1 0 0 1 1 1 0 Laminin Domain II NPV_P10 PF05531.7 ETO08474.1 - 0.16 12.2 5.2 0.87 9.8 0.1 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2968 PF11180.3 ETO08474.1 - 0.17 11.2 11.1 0.37 10.1 7.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) RIG-I_C-RD PF11648.3 ETO08474.1 - 0.19 11.6 3.6 3.4 7.5 0.1 2.7 3 1 1 4 4 2 0 C-terminal domain of RIG-I MIS13 PF08202.6 ETO08474.1 - 0.2 10.6 10.5 0.4 9.7 7.3 1.4 1 0 0 1 1 1 0 Mis12-Mtw1 protein family DUF1664 PF07889.7 ETO08474.1 - 0.29 10.9 10.3 0.09 12.5 2.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) bZIP_1 PF00170.16 ETO08474.1 - 0.29 11.1 15.9 0.53 10.2 4.8 2.7 1 1 1 2 2 2 0 bZIP transcription factor DUF1492 PF07374.6 ETO08474.1 - 0.29 11.2 4.0 0.32 11.1 2.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1492) DMPK_coil PF08826.5 ETO08474.1 - 0.31 10.9 16.6 0.51 10.2 7.7 2.5 1 1 1 2 2 2 0 DMPK coiled coil domain like Transposase_22 PF02994.9 ETO08474.1 - 0.35 9.3 14.6 0.47 8.8 10.1 1.1 1 0 0 1 1 1 0 L1 transposable element M_domain PF12938.2 ETO08474.1 - 0.36 10.6 10.7 0.4 10.4 6.5 1.7 1 1 0 1 1 1 0 M domain of GW182 DUF948 PF06103.6 ETO08474.1 - 0.41 10.5 9.8 1.4 8.8 2.8 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) ERM PF00769.14 ETO08474.1 - 0.41 10.1 16.9 0.61 9.5 11.7 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family CorA PF01544.13 ETO08474.1 - 0.42 9.5 3.1 1 8.2 2.2 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4570 PF15134.1 ETO08474.1 - 0.46 10.3 8.1 0.78 9.6 4.7 2.1 2 1 0 2 2 1 0 Domain of unknown function (DUF4570) DUF724 PF05266.9 ETO08474.1 - 0.47 10.0 15.6 0.67 9.5 10.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) KSR1-SAM PF13543.1 ETO08474.1 - 0.5 10.1 6.8 0.89 9.3 4.7 1.3 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 DUF904 PF06005.7 ETO08474.1 - 0.51 10.6 19.8 4.7 7.5 6.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DUF3450 PF11932.3 ETO08474.1 - 0.53 9.5 10.9 1.1 8.4 7.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) HAUS6_N PF14661.1 ETO08474.1 - 0.54 9.5 8.5 0.74 9.1 5.9 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus FrhB_FdhB_C PF04432.8 ETO08474.1 - 0.62 9.4 5.0 0.35 10.2 0.3 2.4 1 1 1 2 2 2 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus Macoilin PF09726.4 ETO08474.1 - 0.65 8.2 10.5 0.84 7.8 7.3 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF4200 PF13863.1 ETO08474.1 - 0.69 9.8 21.2 0.31 10.9 12.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Tweety PF04906.8 ETO08474.1 - 0.77 8.1 3.4 1 7.6 2.4 1.1 1 0 0 1 1 1 0 Tweety BLOC1_2 PF10046.4 ETO08474.1 - 0.78 9.9 17.4 1.1 9.4 7.1 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2400 PF09674.5 ETO08474.1 - 0.9 9.1 4.5 1.4 8.5 2.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2400) CCDC155 PF14662.1 ETO08474.1 - 0.94 9.0 17.9 2.8 7.4 12.4 1.7 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 Casc1 PF12366.3 ETO08474.1 - 1 8.8 8.9 1.4 8.3 6.2 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 GBP_C PF02841.9 ETO08474.1 - 1.1 8.4 19.3 1.4 8.0 13.4 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF4407 PF14362.1 ETO08474.1 - 1.4 7.8 10.3 1.9 7.3 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) KLRAQ PF10205.4 ETO08474.1 - 1.6 8.8 12.2 3.4 7.7 8.3 1.6 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein Fer4_17 PF13534.1 ETO08474.1 - 1.7 9.0 7.2 18 5.7 3.8 3.0 2 1 0 2 2 2 0 4Fe-4S dicluster domain Tup_N PF08581.5 ETO08474.1 - 1.7 8.8 13.7 0.52 10.5 4.9 2.4 1 1 0 2 2 2 0 Tup N-terminal TMCO5 PF14992.1 ETO08474.1 - 1.7 7.6 14.5 2.4 7.2 10.1 1.1 1 0 0 1 1 1 0 TMCO5 family DUF4140 PF13600.1 ETO08474.1 - 1.8 9.0 9.5 1 9.8 0.7 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF3810 PF12725.2 ETO08474.1 - 1.8 7.3 5.4 2.5 6.9 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Nup54 PF13874.1 ETO08474.1 - 2.1 8.0 11.4 1.6 8.3 6.8 1.6 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF1342 PF07072.6 ETO08474.1 - 2.1 7.9 9.2 2 8.0 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1342) COG2 PF06148.6 ETO08474.1 - 2.1 8.2 11.8 2.3 8.0 2.8 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TSC22 PF01166.13 ETO08474.1 - 2.2 8.3 13.5 1.6 8.7 3.3 2.5 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF3166 PF11365.3 ETO08474.1 - 2.4 8.6 13.5 4.2 7.8 1.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) DUF16 PF01519.11 ETO08474.1 - 2.4 8.4 19.0 0.081 13.1 4.7 2.3 1 1 1 2 2 1 0 Protein of unknown function DUF16 EMP24_GP25L PF01105.19 ETO08474.1 - 2.5 7.7 11.3 0.42 10.3 2.9 2.2 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF812 PF05667.6 ETO08474.1 - 2.6 6.4 16.0 5.3 5.4 10.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Prefoldin_2 PF01920.15 ETO08474.1 - 2.7 7.8 23.2 1.4 8.6 4.1 3.1 1 1 2 3 3 3 0 Prefoldin subunit Mnd1 PF03962.10 ETO08474.1 - 2.7 7.6 15.8 8.8 5.9 10.9 1.8 1 1 0 1 1 1 0 Mnd1 family Vps51 PF08700.6 ETO08474.1 - 2.7 7.8 7.5 32 4.4 1.3 3.0 1 1 2 3 3 3 0 Vps51/Vps67 Adeno_PIX PF03955.9 ETO08474.1 - 2.8 8.5 6.5 12 6.4 0.8 2.4 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) DUF730 PF05325.6 ETO08474.1 - 2.9 7.6 8.9 2.8 7.7 3.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF730) DUF972 PF06156.8 ETO08474.1 - 3 8.2 17.5 1.2e+02 3.0 12.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Nup88 PF10168.4 ETO08474.1 - 3.1 5.5 10.2 4.2 5.0 7.1 1.1 1 0 0 1 1 1 0 Nuclear pore component Kinesin-relat_1 PF12711.2 ETO08474.1 - 3.2 8.2 13.3 16 5.9 6.7 2.9 2 1 1 3 3 3 0 Kinesin motor PEARLI-4 PF05278.7 ETO08474.1 - 3.9 6.7 14.5 1.9 7.7 8.3 1.6 1 1 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Ax_dynein_light PF10211.4 ETO08474.1 - 4.7 7.0 16.7 7.9 6.2 10.7 1.8 1 1 1 2 2 2 0 Axonemal dynein light chain DUF4404 PF14357.1 ETO08474.1 - 5.1 7.5 10.8 3 8.3 2.7 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4404) Occludin_ELL PF07303.8 ETO08474.1 - 5.2 7.8 8.4 14 6.5 5.7 1.8 1 1 0 1 1 1 0 Occludin homology domain LOH1CR12 PF10158.4 ETO08474.1 - 6.2 6.6 7.3 11 5.8 3.4 2.0 1 1 1 2 2 2 0 Tumour suppressor protein ADIP PF11559.3 ETO08474.1 - 6.2 6.7 17.0 25 4.7 8.9 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding eIF3_N PF09440.5 ETO08474.1 - 6.2 6.9 8.9 22 5.2 4.7 2.5 1 1 2 3 3 3 0 eIF3 subunit 6 N terminal domain Med9 PF07544.8 ETO08474.1 - 7.3 6.3 10.5 8.8e+02 -0.3 7.3 2.5 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Uso1_p115_C PF04871.8 ETO08474.1 - 9.4 6.1 17.5 0.77 9.6 2.0 2.2 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region PCI PF01399.22 ETO08475.1 - 1.5e-12 47.7 0.1 5.1e-12 46.0 0.1 2.0 1 0 0 1 1 1 1 PCI domain TPR_1 PF00515.23 ETO08475.1 - 0.0049 16.4 0.8 0.013 15.0 0.3 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Paf67 PF10255.4 ETO08475.1 - 0.013 14.4 5.2 0.77 8.5 0.3 2.2 2 0 0 2 2 2 0 RNA polymerase I-associated factor PAF67 Mt_ATP-synt_D PF05873.7 ETO08475.1 - 0.047 13.3 0.4 0.14 11.7 0.2 1.8 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) RasGEF PF00617.14 ETO08475.1 - 0.052 13.2 0.7 0.24 11.0 0.1 2.0 1 1 1 2 2 2 0 RasGEF domain OSTbeta PF15048.1 ETO08478.1 - 0.04 13.9 2.4 0.062 13.3 0.7 2.0 1 1 0 1 1 1 0 Organic solute transporter subunit beta protein NUMOD1 PF07453.8 ETO08479.1 - 0.0066 16.2 0.1 0.017 14.9 0.1 1.8 1 0 0 1 1 1 1 NUMOD1 domain BUD22 PF09073.5 ETO08480.1 - 0.00014 21.0 22.6 0.00019 20.6 15.7 1.0 1 0 0 1 1 1 1 BUD22 Ycf1 PF05758.7 ETO08480.1 - 0.0088 13.8 10.5 0.011 13.5 7.3 1.0 1 0 0 1 1 1 1 Ycf1 Zip PF02535.17 ETO08480.1 - 0.05 12.6 0.7 0.064 12.2 0.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.7 ETO08480.1 - 0.055 11.3 30.0 0.071 11.0 20.8 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 ETO08480.1 - 0.076 11.7 23.9 0.1 11.3 16.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SAPS PF04499.10 ETO08480.1 - 0.091 11.3 13.6 0.11 11.0 9.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NOA36 PF06524.7 ETO08480.1 - 0.23 10.7 19.2 0.34 10.1 13.3 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-T PF15511.1 ETO08480.1 - 0.35 10.0 14.5 0.41 9.8 10.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CDC45 PF02724.9 ETO08480.1 - 0.36 8.8 23.3 0.44 8.5 16.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 ETO08480.1 - 0.72 9.1 24.1 1.2 8.4 16.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DDHD PF02862.12 ETO08480.1 - 1 9.1 8.8 1.3 8.8 6.1 1.2 1 0 0 1 1 1 0 DDHD domain Daxx PF03344.10 ETO08480.1 - 1.1 7.6 28.5 1.4 7.3 19.8 1.0 1 0 0 1 1 1 0 Daxx Family Astro_capsid PF03115.9 ETO08480.1 - 1.1 7.4 5.6 1.2 7.3 3.9 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Gag_spuma PF03276.9 ETO08480.1 - 1.2 7.4 6.5 1.4 7.1 4.5 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DUF2890 PF11081.3 ETO08480.1 - 4.4 7.3 18.1 7.4 6.5 12.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Rhabdo_ncap PF00945.13 ETO08480.1 - 5.4 5.4 10.3 7 5.1 7.1 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein CobT PF06213.7 ETO08480.1 - 5.8 5.9 23.1 7.7 5.5 16.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2151 PF10221.4 ETO08480.1 - 7.2 4.6 12.3 8.8 4.3 8.6 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator DUF221 PF02714.10 ETO08481.1 - 4.2e-37 127.7 30.7 3.5e-20 72.1 15.7 3.2 2 1 1 3 3 3 2 Domain of unknown function DUF221 IBN_N PF03810.14 ETO08482.1 - 0.00049 19.9 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 Importin-beta N-terminal domain 3H PF02829.9 ETO08483.1 - 0.029 14.3 0.3 4.6 7.3 0.0 2.5 2 0 0 2 2 2 0 3H domain DUF3848 PF12959.2 ETO08484.1 - 0.0059 16.5 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3848) PAT1 PF09770.4 ETO08484.1 - 0.12 10.5 26.3 0.13 10.4 18.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_23 PF13476.1 ETO08484.1 - 0.79 10.0 6.6 1.1 9.6 4.6 1.2 1 0 0 1 1 1 0 AAA domain DUF4557 PF15101.1 ETO08484.1 - 2.2 8.0 11.2 3.9 7.2 7.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF4407 PF14362.1 ETO08484.1 - 4.9 6.0 10.3 7.7 5.3 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PAP2_3 PF14378.1 ETO08485.1 - 0.25 10.8 8.5 0.95 8.9 1.3 2.4 2 1 0 2 2 2 0 PAP2 superfamily DUF4131 PF13567.1 ETO08485.1 - 1.6 8.1 8.1 1.6 8.0 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) YwiC PF14256.1 ETO08485.1 - 7.6 6.6 10.5 7.7 6.6 1.3 2.3 2 0 0 2 2 2 0 YwiC-like protein HEAT PF02985.17 ETO08486.1 - 0.01 15.8 0.0 1.3 9.3 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat Spot_14 PF07084.7 ETO08486.1 - 0.016 15.1 2.5 0.016 15.1 1.8 2.7 3 0 0 3 3 3 0 Thyroid hormone-inducible hepatic protein Spot 14 CBF PF03914.12 ETO08486.1 - 0.046 13.1 0.7 5.7 6.3 0.0 2.7 2 0 0 2 2 2 0 CBF/Mak21 family Hom_end_hint PF05203.11 ETO08486.1 - 0.65 9.6 4.6 7.1 6.2 0.8 2.2 2 0 0 2 2 2 0 Hom_end-associated Hint RNA_pol_Rpc4 PF05132.9 ETO08486.1 - 0.82 9.6 12.2 6 6.8 3.3 3.2 3 0 0 3 3 3 0 RNA polymerase III RPC4 Zip PF02535.17 ETO08486.1 - 8.8 5.2 6.8 1.3 7.9 1.5 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter ASFV_p27 PF06556.6 ETO08487.1 - 0.0053 16.6 1.7 0.0065 16.3 0.2 1.8 2 0 0 2 2 2 1 IAP-like protein p27 C-terminus 2C_adapt PF08793.5 ETO08487.1 - 0.1 12.5 0.0 0.31 10.9 0.0 1.8 1 0 0 1 1 1 0 2-cysteine adaptor domain AAA_14 PF13173.1 ETO08487.1 - 0.29 11.0 2.9 11 5.8 0.0 2.7 2 1 1 3 3 3 0 AAA domain DUF4401 PF14351.1 ETO08488.1 - 0.0095 14.9 2.6 0.0095 14.9 1.8 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4401) Cytochrom_B_C PF00032.12 ETO08488.1 - 0.032 14.4 4.3 0.46 10.7 3.2 2.5 1 1 1 2 2 2 0 Cytochrome b(C-terminal)/b6/petD DUF2975 PF11188.3 ETO08488.1 - 3.9 7.1 9.8 1.1 8.9 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) MARVEL PF01284.18 ETO08488.1 - 6 6.6 11.8 2.1 8.1 5.1 2.5 2 1 0 2 2 2 0 Membrane-associating domain Pilt PF15453.1 ETO08489.1 - 6.8 6.2 16.9 8.6 5.9 11.7 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Peptidase_S28 PF05577.7 ETO08490.1 - 1.7e-18 66.4 0.2 2.1e-18 66.1 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Tctex-1 PF03645.8 ETO08491.1 - 1.7e-26 92.0 0.6 1.9e-26 91.8 0.4 1.0 1 0 0 1 1 1 1 Tctex-1 family PTPS_related PF10131.4 ETO08494.1 - 0.0037 15.4 0.5 0.0047 15.1 0.3 1.2 1 0 0 1 1 1 1 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein Ni_hydr_CYTB PF01292.15 ETO08494.1 - 0.005 16.2 0.4 0.0099 15.2 0.2 1.6 1 1 1 2 2 2 1 Prokaryotic cytochrome b561 YfhO PF09586.5 ETO08494.1 - 0.35 8.8 2.5 0.46 8.4 1.7 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF4131 PF13567.1 ETO08494.1 - 7.7 5.8 8.0 68 2.7 5.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Tudor-knot PF11717.3 ETO08495.1 - 0.0057 16.3 5.9 0.05 13.3 2.5 2.7 2 1 0 2 2 2 1 RNA binding activity-knot of a chromodomain Chlam_PMP PF02415.12 ETO08496.1 - 0.00027 21.0 20.6 0.027 14.7 0.2 6.0 7 0 0 7 7 7 3 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat SET PF00856.23 ETO08497.1 - 0.045 14.0 0.3 0.045 14.0 0.2 3.4 2 1 0 2 2 2 0 SET domain Mitofilin PF09731.4 ETO08497.1 - 0.7 8.4 53.9 1 7.9 37.3 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Utp14 PF04615.8 ETO08497.1 - 9.4 4.2 72.8 14 3.7 50.5 1.1 1 0 0 1 1 1 0 Utp14 protein SET PF00856.23 ETO08498.1 - 0.00013 22.3 0.0 0.00019 21.8 0.0 1.3 1 0 0 1 1 1 1 SET domain Kelch_6 PF13964.1 ETO08499.1 - 0.00019 21.4 0.4 0.00019 21.4 0.3 3.7 4 1 1 5 5 5 1 Kelch motif Kelch_1 PF01344.20 ETO08499.1 - 0.00031 20.2 1.9 0.0032 16.9 0.2 3.0 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETO08499.1 - 0.0027 17.4 2.8 0.071 12.8 0.0 3.4 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO08499.1 - 0.0033 17.1 1.6 0.17 11.6 0.1 3.6 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 ETO08499.1 - 0.035 14.0 5.6 0.07 13.1 0.4 3.3 4 0 0 4 4 4 0 Kelch motif Kelch_3 PF13415.1 ETO08499.1 - 0.68 10.1 2.3 2 8.6 0.1 2.8 4 0 0 4 4 4 0 Galactose oxidase, central domain FH2 PF02181.18 ETO08500.1 - 0.00016 20.7 5.5 0.00016 20.7 3.8 3.1 1 1 2 3 3 3 3 Formin Homology 2 Domain WD40 PF00400.27 ETO08501.1 - 3.5e-100 324.6 28.7 4.5e-14 51.7 0.3 11.0 11 0 0 11 11 11 9 WD domain, G-beta repeat NACHT PF05729.7 ETO08501.1 - 1.3e-11 44.4 0.0 2.9e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Nup160 PF11715.3 ETO08501.1 - 2e-08 32.8 17.4 0.36 8.9 0.2 7.7 2 2 3 7 7 7 5 Nucleoporin Nup120/160 Pentapeptide PF00805.17 ETO08501.1 - 1.3e-06 27.4 1.5 2.9e-06 26.3 1.0 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO08501.1 - 6.8e-06 25.8 1.4 1.4e-05 24.7 0.4 2.0 2 0 0 2 2 1 1 Pentapeptide repeats (9 copies) AAA_18 PF13238.1 ETO08501.1 - 5.1e-05 23.5 0.0 5.1e-05 23.5 0.0 3.6 2 2 1 3 3 3 1 AAA domain Pentapeptide_3 PF13576.1 ETO08501.1 - 5.8e-05 22.8 0.6 0.00021 21.0 0.4 2.0 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA_22 PF13401.1 ETO08501.1 - 6.6e-05 23.0 0.0 0.00022 21.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain Str_synth PF03088.11 ETO08501.1 - 0.0014 18.6 0.1 1.4 8.9 0.0 4.4 4 1 0 4 4 3 1 Strictosidine synthase RNA_helicase PF00910.17 ETO08501.1 - 0.0019 18.3 3.0 0.2 11.8 0.0 3.4 2 1 1 3 3 3 1 RNA helicase PD40 PF07676.7 ETO08501.1 - 0.0021 17.6 5.8 9.7 5.9 0.1 4.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat UPF0079 PF02367.12 ETO08501.1 - 0.0047 16.5 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 ETO08501.1 - 0.0057 17.4 1.9 0.032 15.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA PF00004.24 ETO08501.1 - 0.0067 16.6 0.0 0.35 11.0 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETO08501.1 - 0.017 15.1 0.4 0.12 12.3 0.1 2.5 2 1 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 ETO08501.1 - 0.047 13.9 0.4 0.21 11.8 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.1 ETO08501.1 - 0.06 13.2 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 ETO08501.1 - 0.065 12.9 0.0 0.27 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) HSP70 PF00012.15 ETO08503.1 - 3.4e-06 25.2 9.7 3.4e-06 25.2 6.7 2.6 2 1 0 2 2 2 1 Hsp70 protein Pex14_N PF04695.8 ETO08503.1 - 0.79 9.7 14.3 0.2 11.7 0.5 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AbiH PF14253.1 ETO08503.1 - 1.7 8.1 14.9 4.9 6.6 9.3 2.5 1 1 0 1 1 1 0 Bacteriophage abortive infection AbiH HSP70 PF00012.15 ETO08504.1 - 1.3e-94 317.3 2.6 1.3e-65 221.4 0.4 4.0 2 1 1 3 3 3 3 Hsp70 protein MreB_Mbl PF06723.8 ETO08504.1 - 0.00017 20.3 0.0 0.0003 19.5 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein WD40 PF00400.27 ETO08506.1 - 2.7e-58 191.8 20.9 1.3e-11 43.8 0.2 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO08506.1 - 1.1e-09 37.0 8.8 0.032 12.3 0.0 5.1 1 1 4 5 5 5 5 Nucleoporin Nup120/160 HAD PF12710.2 ETO08506.1 - 0.01 15.9 3.8 7.8 6.6 1.3 3.8 1 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase DUF1900 PF08954.6 ETO08506.1 - 0.032 13.7 0.0 3 7.3 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1900) Kri1_C PF12936.2 ETO08507.1 - 0.69 9.8 11.1 1.2 9.0 5.2 3.1 1 1 1 2 2 2 0 KRI1-like family C-terminal WD40 PF00400.27 ETO08508.1 - 1.2e-68 224.6 11.0 4.9e-13 48.4 0.1 6.7 6 1 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO08508.1 - 9.7e-06 23.9 6.7 0.077 11.1 0.8 4.1 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO08508.1 - 0.00034 19.0 0.1 0.12 10.6 0.0 2.3 2 0 0 2 2 2 2 Cytochrome D1 heme domain DUF3601 PF12208.3 ETO08508.1 - 0.00063 19.6 0.1 3.2 7.7 0.0 3.8 2 1 2 4 4 4 1 Domain of unknown function (DUF3601) Resistin PF06954.6 ETO08508.1 - 0.0019 18.4 0.3 17 5.7 0.0 3.8 2 2 0 3 3 3 0 Resistin DPPIV_N PF00930.16 ETO08508.1 - 0.0074 14.9 0.1 0.36 9.3 0.1 2.4 1 1 1 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.7 ETO08508.1 - 0.011 15.4 6.5 5 6.9 0.1 4.8 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO08508.1 - 0.017 14.5 0.1 0.09 12.2 0.0 2.2 1 1 0 1 1 1 0 PQQ-like domain Nbas_N PF15492.1 ETO08508.1 - 0.017 14.2 1.0 23 3.9 0.0 3.8 2 2 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Sporozoite_P67 PF05642.6 ETO08510.1 - 0.64 7.8 7.6 0.76 7.5 5.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.9 ETO08510.1 - 0.65 7.9 11.5 0.76 7.7 8.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2201_N PF13203.1 ETO08510.1 - 1.8 7.6 6.5 2.2 7.3 4.5 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Kelch_1 PF01344.20 ETO08511.1 - 0.0038 16.7 0.6 0.028 13.9 0.0 2.3 2 1 0 2 2 2 1 Kelch motif Kelch_4 PF13418.1 ETO08511.1 - 0.0054 16.4 0.0 0.051 13.3 0.0 2.2 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO08511.1 - 0.051 13.7 0.0 1.9 8.7 0.0 2.4 2 0 0 2 2 2 0 Kelch motif Viral_Beta_CD PF04530.7 ETO08511.1 - 0.099 12.8 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Viral Beta C/D like family WD40 PF00400.27 ETO08512.1 - 2.2e-51 169.9 12.2 4.7e-10 38.9 1.1 6.0 7 0 0 7 7 7 5 WD domain, G-beta repeat PQQ_2 PF13360.1 ETO08512.1 - 0.0023 17.4 0.3 1.5 8.2 0.0 2.2 1 1 1 2 2 2 2 PQQ-like domain Nup160 PF11715.3 ETO08512.1 - 0.0055 14.8 4.5 0.26 9.3 0.1 3.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 ETO08512.1 - 0.0062 15.6 0.3 2 7.4 0.0 2.8 1 1 3 4 4 4 2 Neuroblastoma-amplified sequence, N terminal WD40 PF00400.27 ETO08513.1 - 1e-29 101.2 1.7 5.9e-11 41.8 0.1 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO08513.1 - 0.00016 19.9 0.7 0.17 9.9 0.1 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DPPIV_N PF00930.16 ETO08513.1 - 0.0057 15.2 0.4 0.17 10.4 0.0 2.2 1 1 1 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nbas_N PF15492.1 ETO08513.1 - 0.033 13.2 0.1 12 4.8 0.0 2.7 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PH PF00169.24 ETO08514.1 - 5e-12 45.9 21.2 2.7e-08 33.9 0.6 4.1 3 3 0 3 3 3 2 PH domain PH_11 PF15413.1 ETO08514.1 - 5.4e-09 36.2 12.7 6e-06 26.4 0.1 3.8 3 1 0 3 3 3 2 Pleckstrin homology domain Mcp5_PH PF12814.2 ETO08514.1 - 0.013 15.3 1.6 8.7 6.2 0.0 3.5 3 1 0 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology PH_2 PF08458.5 ETO08514.1 - 0.056 13.3 0.3 2.3 8.1 0.0 2.4 2 0 0 2 2 2 0 Plant pleckstrin homology-like region Macoilin PF09726.4 ETO08514.1 - 0.21 9.8 23.3 0.37 9.0 16.2 1.3 1 0 0 1 1 1 0 Transmembrane protein Tim54 PF11711.3 ETO08514.1 - 7 5.1 11.7 3.4 6.1 1.5 2.5 3 0 0 3 3 3 0 Inner membrane protein import complex subunit Tim54 IncA PF04156.9 ETO08518.1 - 0.0086 15.6 13.5 0.0086 15.6 9.4 1.5 2 0 0 2 2 1 1 IncA protein Reo_sigmaC PF04582.7 ETO08518.1 - 0.012 14.7 2.8 0.015 14.5 1.9 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF3164 PF11363.3 ETO08518.1 - 0.013 14.8 6.1 0.082 12.2 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3164) DUF641 PF04859.7 ETO08518.1 - 0.026 14.2 13.4 0.23 11.2 2.6 2.6 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Flagellar_rod PF05149.7 ETO08518.1 - 0.035 13.3 17.2 0.055 12.6 11.9 1.3 1 0 0 1 1 1 0 Paraflagellar rod protein DUF883 PF05957.8 ETO08518.1 - 0.064 13.6 5.1 0.36 11.2 0.6 2.6 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF883) SapB_1 PF05184.10 ETO08518.1 - 0.1 12.4 2.5 8.8 6.2 0.1 3.1 2 0 0 2 2 2 0 Saposin-like type B, region 1 YPEB PF14620.1 ETO08518.1 - 0.15 11.0 11.9 0.24 10.3 8.2 1.3 1 0 0 1 1 1 0 YpeB sporulation Baculo_PEP_C PF04513.7 ETO08518.1 - 0.16 11.8 15.6 1.5 8.6 10.7 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-Q PF13094.1 ETO08518.1 - 0.17 11.8 20.7 0.043 13.8 11.3 2.0 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Spc7 PF08317.6 ETO08518.1 - 0.18 10.4 23.6 1 7.9 16.4 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein ATP-synt_B PF00430.13 ETO08518.1 - 0.2 11.4 14.9 0.34 10.7 10.3 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Fib_alpha PF08702.5 ETO08518.1 - 0.36 10.9 25.1 4.3 7.4 15.9 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DASH_Spc34 PF08657.5 ETO08518.1 - 0.5 9.9 18.6 0.73 9.4 12.8 1.5 1 1 0 1 1 1 0 DASH complex subunit Spc34 DUF812 PF05667.6 ETO08518.1 - 0.53 8.7 19.7 2.9 6.2 13.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF4618 PF15397.1 ETO08518.1 - 0.57 9.4 27.3 0.067 12.5 6.8 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) YjcZ PF13990.1 ETO08518.1 - 0.68 9.0 5.9 1.3 8.0 4.1 1.5 1 0 0 1 1 1 0 YjcZ-like protein DivIVA PF05103.8 ETO08518.1 - 0.7 9.9 18.7 0.069 13.2 9.4 1.9 2 0 0 2 2 2 0 DivIVA protein AAA_13 PF13166.1 ETO08518.1 - 0.79 8.1 23.9 1 7.7 16.5 1.1 1 0 0 1 1 1 0 AAA domain YtxH PF12732.2 ETO08518.1 - 0.87 10.0 11.2 5.9 7.3 2.2 2.9 3 0 0 3 3 3 0 YtxH-like protein AcylCoA_dehyd_C PF12186.3 ETO08518.1 - 0.93 9.3 9.5 6.4 6.6 0.6 3.3 1 1 3 4 4 4 0 Acyl-CoA dehydrogenase C terminal V_ATPase_I PF01496.14 ETO08518.1 - 0.97 7.2 11.2 1.1 7.0 7.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF327 PF03885.8 ETO08518.1 - 1.1 9.0 21.6 0.17 11.7 10.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF327) DUF3450 PF11932.3 ETO08518.1 - 1.2 8.3 14.3 1.7 7.8 9.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Jnk-SapK_ap_N PF09744.4 ETO08518.1 - 1.9 8.4 22.6 0.1 12.5 10.9 2.0 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Atg14 PF10186.4 ETO08518.1 - 2.3 7.0 22.0 24 3.7 15.2 2.2 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SlyX PF04102.7 ETO08518.1 - 2.4 8.5 19.0 5.1 7.5 4.3 2.9 1 1 1 2 2 2 0 SlyX DUF4200 PF13863.1 ETO08518.1 - 2.6 8.0 26.7 0.59 10.0 12.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF3508 PF12018.3 ETO08518.1 - 2.6 6.9 16.6 6.5 5.6 10.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3508) Lipoprotein_20 PF13942.1 ETO08518.1 - 2.9 7.4 13.2 6.2 6.3 9.1 1.7 1 1 0 1 1 1 0 YfhG lipoprotein HAUS-augmin3 PF14932.1 ETO08518.1 - 3.2 6.8 19.8 0.79 8.8 11.1 1.7 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 Vps51 PF08700.6 ETO08518.1 - 3.4 7.5 16.1 11 5.9 6.8 3.0 2 1 1 3 3 2 0 Vps51/Vps67 DUF948 PF06103.6 ETO08518.1 - 3.5 7.5 18.3 4.4 7.2 4.1 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4407 PF14362.1 ETO08518.1 - 4.1 6.2 11.0 6.2 5.6 7.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TMP_2 PF06791.8 ETO08518.1 - 4.2 6.9 7.7 1.1 8.8 1.1 2.0 1 1 1 2 2 2 0 Prophage tail length tape measure protein Ran-binding PF05508.6 ETO08518.1 - 4.5 6.0 20.2 3.9 6.2 7.1 2.3 1 1 1 2 2 2 0 RanGTP-binding protein Rootletin PF15035.1 ETO08518.1 - 5.1 7.0 18.3 24 4.8 12.7 2.2 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion BLOC1_2 PF10046.4 ETO08518.1 - 5.9 7.0 24.0 12 6.0 8.0 3.4 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.7 ETO08518.1 - 6 6.6 25.3 4.2 7.1 14.4 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 ETO08518.1 - 7.3 5.5 21.8 0.3 10.0 11.2 1.5 2 0 0 2 2 2 0 Autophagy protein Apg6 Tropomyosin_1 PF12718.2 ETO08518.1 - 8.4 6.2 27.2 0.29 10.9 10.2 2.9 1 1 1 3 3 3 0 Tropomyosin like RNA_pol_Rpb4 PF03874.11 ETO08519.1 - 0.09 12.7 3.5 0.17 11.9 2.4 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb4 Methyltransf_12 PF08242.7 ETO08519.1 - 0.76 10.2 4.2 1.6 9.2 2.9 1.5 1 0 0 1 1 1 0 Methyltransferase domain ubiquitin PF00240.18 ETO08520.1 - 2.1e-10 39.8 8.6 5.5e-06 25.6 0.3 2.8 2 1 1 3 3 3 2 Ubiquitin family Ubiquitin_2 PF14560.1 ETO08520.1 - 1.8e-05 24.8 1.6 4.9e-05 23.4 1.1 1.8 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.3 ETO08520.1 - 0.00039 20.0 12.5 0.0071 16.0 0.5 3.2 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like DUF3474 PF11960.3 ETO08520.1 - 0.13 12.2 1.0 1.5 8.8 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) UN_NPL4 PF11543.3 ETO08520.1 - 0.13 12.5 8.8 0.29 11.4 2.8 2.8 2 1 0 2 2 2 0 Nuclear pore localisation protein NPL4 SAP18 PF06487.7 ETO08520.1 - 0.19 11.4 3.0 1 9.2 0.3 2.5 2 1 0 2 2 2 0 Sin3 associated polypeptide p18 (SAP18) zf-RanBP PF00641.13 ETO08521.1 - 8.9e-05 21.5 2.6 8.9e-05 21.5 1.8 2.8 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others DZR PF12773.2 ETO08521.1 - 4.8 7.0 11.8 5 7.0 1.8 2.5 2 0 0 2 2 2 0 Double zinc ribbon Ras PF00071.17 ETO08522.1 - 1.4e-14 53.8 0.0 2.4e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO08522.1 - 0.011 16.1 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein Arf PF00025.16 ETO08522.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family Sec63 PF02889.11 ETO08523.1 - 4.9e-66 223.1 0.0 6.6e-66 222.6 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain Helicase_C PF00271.26 ETO08523.1 - 0.00011 21.9 0.0 0.00046 20.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HHH_5 PF14520.1 ETO08523.1 - 0.04 14.1 0.0 0.2 11.8 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain DUF898 PF05987.8 ETO08524.1 - 0.054 12.3 4.5 0.18 10.6 3.1 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) CAF-1_p150 PF11600.3 ETO08525.1 - 0.011 15.0 25.5 0.011 15.0 17.7 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal LMBR1 PF04791.11 ETO08525.1 - 4 5.9 5.1 0.54 8.7 0.5 1.7 2 0 0 2 2 2 0 LMBR1-like membrane protein HNH_4 PF13395.1 ETO08526.1 - 0.19 11.3 0.9 1.6 8.4 0.1 2.3 2 0 0 2 2 2 0 HNH endonuclease Radial_spoke PF04712.7 ETO08527.1 - 7e-69 232.8 9.0 3e-34 118.6 0.5 3.7 2 2 0 2 2 2 2 Radial spokehead-like protein YgaB PF14182.1 ETO08528.1 - 0.063 13.5 0.4 0.18 12.0 0.2 1.8 1 1 1 2 2 2 0 YgaB-like protein cNMP_binding PF00027.24 ETO08529.1 - 1.5e-08 34.3 0.0 3.4e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Popeye PF04831.8 ETO08529.1 - 0.00015 21.5 0.6 0.00063 19.5 0.1 2.0 1 1 1 2 2 2 1 Popeye protein conserved region Herpes_gI PF01688.12 ETO08529.1 - 0.0073 15.4 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein I RIO1 PF01163.17 ETO08530.1 - 0.025 13.9 0.0 0.15 11.4 0.1 2.0 2 0 0 2 2 2 0 RIO1 family APH PF01636.18 ETO08530.1 - 0.089 12.5 0.0 0.27 10.9 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family ADIP PF11559.3 ETO08531.1 - 0.0013 18.6 8.7 0.0028 17.5 0.7 2.7 1 1 2 3 3 3 1 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 ETO08531.1 - 0.0048 16.7 6.9 0.0048 16.7 4.8 2.1 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EzrA PF06160.7 ETO08531.1 - 0.0071 14.5 6.5 0.01 14.0 4.5 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA FbpA PF05833.6 ETO08531.1 - 0.0087 14.6 1.0 0.011 14.3 0.7 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Reo_sigmaC PF04582.7 ETO08531.1 - 0.012 14.8 0.2 0.012 14.8 0.2 1.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Filament PF00038.16 ETO08531.1 - 0.027 13.9 5.4 0.035 13.5 3.7 1.2 1 0 0 1 1 1 0 Intermediate filament protein TMF_DNA_bd PF12329.3 ETO08531.1 - 0.028 14.2 5.8 1.8 8.4 0.1 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 ETO08531.1 - 0.04 12.9 7.8 0.064 12.2 5.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 ETO08531.1 - 0.051 13.3 9.4 0.059 13.1 2.9 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF641 PF04859.7 ETO08531.1 - 0.13 11.9 3.4 0.17 11.6 0.7 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) WEMBL PF05701.6 ETO08531.1 - 0.14 10.5 6.7 0.17 10.2 4.7 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light ERM PF00769.14 ETO08531.1 - 0.19 11.2 8.7 0.033 13.7 3.7 1.4 2 0 0 2 2 2 0 Ezrin/radixin/moesin family IncA PF04156.9 ETO08531.1 - 0.19 11.2 9.2 0.22 11.1 5.5 1.6 1 1 1 2 2 2 0 IncA protein GAS PF13851.1 ETO08531.1 - 0.22 10.6 7.8 0.26 10.4 4.9 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF869 PF05911.6 ETO08531.1 - 0.26 9.4 12.0 0.26 9.4 7.3 1.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) CCDC92 PF14916.1 ETO08531.1 - 0.4 10.3 4.2 0.52 9.9 0.2 2.7 2 1 0 2 2 2 0 Coiled-coil domain of unknown function THOC7 PF05615.8 ETO08531.1 - 0.54 10.5 5.7 1.8 8.8 3.8 1.8 1 1 0 1 1 1 0 Tho complex subunit 7 HR1 PF02185.11 ETO08531.1 - 0.54 10.0 0.1 0.54 10.0 0.1 3.4 3 1 0 3 3 3 0 Hr1 repeat DUF342 PF03961.8 ETO08531.1 - 0.62 8.4 3.6 0.9 7.8 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Prefoldin_2 PF01920.15 ETO08531.1 - 0.65 9.7 12.0 0.61 9.8 1.1 3.3 1 1 2 3 3 3 0 Prefoldin subunit Microtub_bind PF13931.1 ETO08531.1 - 1.1 9.4 4.6 0.5 10.5 1.3 1.8 1 1 1 2 2 2 0 Kinesin-associated microtubule-binding DUF724 PF05266.9 ETO08531.1 - 1.7 8.2 11.4 5.1 6.6 6.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Snapin_Pallidin PF14712.1 ETO08531.1 - 2.3 8.5 6.4 0.43 10.9 1.1 2.3 2 2 0 2 2 2 0 Snapin/Pallidin DUF1162 PF06650.7 ETO08532.1 - 3.4e-06 26.4 1.9 0.019 14.1 0.0 3.5 3 1 0 3 3 3 2 Protein of unknown function (DUF1162) Flp_C PF05202.7 ETO08532.1 - 0.0019 17.4 0.9 0.0041 16.3 0.6 1.5 1 0 0 1 1 1 1 Recombinase Flp protein SR-25 PF10500.4 ETO08532.1 - 1.3 8.3 10.3 2.2 7.6 7.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.20 ETO08533.1 - 3.4e-14 52.6 0.0 3.4e-14 52.6 0.0 2.4 3 0 0 3 3 3 1 Protein kinase domain DUF1162 PF06650.7 ETO08534.1 - 0.0091 15.2 0.2 0.031 13.5 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1162) ATG_C PF09333.6 ETO08535.1 - 2.5e-07 30.7 0.0 5.9e-07 29.5 0.0 1.5 2 0 0 2 2 2 1 ATG C terminal domain Laminin_G_3 PF13385.1 ETO08536.1 - 7.9e-09 35.9 0.0 1.4e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily zf-DHHC PF01529.15 ETO08537.1 - 2.3e-32 111.7 12.4 5.8e-31 107.2 8.6 2.4 1 1 0 1 1 1 1 DHHC palmitoyltransferase PBP1_TM PF14812.1 ETO08537.1 - 0.016 15.4 10.5 0.057 13.7 7.2 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Prothymosin PF03247.9 ETO08537.1 - 0.14 12.3 17.9 0.2 11.8 12.4 1.1 1 0 0 1 1 1 0 Prothymosin/parathymosin family Cwf_Cwc_15 PF04889.7 ETO08537.1 - 0.14 11.8 12.7 0.2 11.3 8.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Astro_capsid PF03115.9 ETO08537.1 - 0.15 10.2 1.9 0.2 9.8 1.3 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF3245 PF11595.3 ETO08537.1 - 0.21 11.8 9.8 0.33 11.2 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Sigma70_ner PF04546.8 ETO08537.1 - 0.25 10.9 8.3 0.36 10.4 5.8 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 ETO08537.1 - 0.88 7.5 8.6 1.2 7.1 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.6 ETO08537.1 - 2 8.1 10.1 4 7.2 7.0 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal BTV_NS2 PF04514.7 ETO08537.1 - 2.3 7.0 8.2 3.2 6.5 5.7 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Daxx PF03344.10 ETO08537.1 - 3.6 5.9 11.5 4.6 5.6 8.0 1.0 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 ETO08537.1 - 5.1 5.7 17.2 6.7 5.3 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 ETO08537.1 - 9 5.8 10.8 14 5.1 7.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 ETO08539.1 - 2.8e-05 22.3 9.3 3.6e-05 21.9 6.4 1.2 1 0 0 1 1 1 1 Nop14-like family DUF2457 PF10446.4 ETO08539.1 - 7.7e-05 21.6 13.5 7.7e-05 21.6 9.3 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) TFIIA PF03153.8 ETO08539.1 - 0.0015 18.5 13.0 0.0017 18.3 8.6 1.4 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4366 PF14283.1 ETO08539.1 - 0.0016 17.9 0.4 0.0025 17.2 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) FAM176 PF14851.1 ETO08539.1 - 0.069 12.8 7.5 0.12 12.0 2.3 2.4 2 0 0 2 2 2 0 FAM176 family TRAP_alpha PF03896.11 ETO08539.1 - 0.49 9.3 6.6 0.27 10.1 2.6 1.9 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.9 ETO08539.1 - 2.9 5.8 22.3 0.62 8.0 12.3 1.8 2 0 0 2 2 2 0 CDC45-like protein Nucleoplasmin PF03066.10 ETO08539.1 - 3.1 7.3 24.3 2 7.9 12.9 2.2 2 0 0 2 2 2 0 Nucleoplasmin Tom37_C PF11801.3 ETO08539.1 - 4.7 7.0 8.8 7.3 6.4 3.0 2.2 2 0 0 2 2 2 0 Tom37 C-terminal domain PRP21_like_P PF12230.3 ETO08539.1 - 8.3 5.8 17.9 2.1 7.7 4.8 2.4 3 0 0 3 3 3 0 Pre-mRNA splicing factor PRP21 like protein TIP49 PF06068.8 ETO08540.1 - 1.4e-131 438.8 12.9 7.7e-79 265.2 0.3 2.3 1 1 1 2 2 2 2 TIP49 C-terminus AAA PF00004.24 ETO08540.1 - 7.7e-10 39.0 1.2 5.7e-07 29.7 0.2 2.7 1 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETO08540.1 - 3.3e-08 33.7 0.0 1e-07 32.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 ETO08540.1 - 4.1e-08 33.4 0.6 0.0012 18.9 0.4 2.9 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.7 ETO08540.1 - 4.2e-06 25.9 5.1 0.0017 17.4 0.1 3.4 3 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 ETO08540.1 - 4.7e-06 26.3 1.7 0.00074 19.2 0.1 2.8 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) DnaB_C PF03796.10 ETO08540.1 - 2.6e-05 23.2 0.0 5.4e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_25 PF13481.1 ETO08540.1 - 5.2e-05 22.7 0.3 0.00019 20.8 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETO08540.1 - 0.00054 20.2 0.2 0.0014 18.9 0.1 1.8 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 ETO08540.1 - 0.00066 18.9 0.5 0.015 14.4 0.2 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 ETO08540.1 - 0.00085 18.8 0.4 0.18 11.2 0.1 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.1 ETO08540.1 - 0.0014 18.3 0.1 0.0044 16.7 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain DNA_pol3_delta2 PF13177.1 ETO08540.1 - 0.0018 17.9 0.2 0.0049 16.5 0.1 1.7 1 0 0 1 1 1 1 DNA polymerase III, delta subunit NACHT PF05729.7 ETO08540.1 - 0.002 17.7 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain KaiC PF06745.8 ETO08540.1 - 0.0031 16.6 0.1 0.0077 15.3 0.0 1.8 1 0 0 1 1 1 1 KaiC DUF2075 PF09848.4 ETO08540.1 - 0.0036 16.3 0.2 0.0074 15.2 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.15 ETO08540.1 - 0.0057 16.3 0.0 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_17 PF13207.1 ETO08540.1 - 0.011 16.5 0.3 0.06 14.1 0.1 2.4 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 ETO08540.1 - 0.013 14.6 0.3 0.033 13.2 0.2 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.1 ETO08540.1 - 0.014 15.0 0.1 0.023 14.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 ETO08540.1 - 0.014 15.0 0.1 0.035 13.7 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 ETO08540.1 - 0.014 15.6 0.3 0.032 14.5 0.2 1.7 1 0 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.12 ETO08540.1 - 0.016 14.6 0.1 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Zot PF05707.7 ETO08540.1 - 0.016 14.6 0.1 3.1 7.2 0.0 2.6 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_30 PF13604.1 ETO08540.1 - 0.017 14.6 0.2 0.1 12.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 ETO08540.1 - 0.018 15.1 0.1 0.1 12.7 0.0 2.3 1 1 1 2 2 2 0 RNA helicase Parvo_NS1 PF01057.12 ETO08540.1 - 0.02 13.7 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KTI12 PF08433.5 ETO08540.1 - 0.03 13.5 0.0 0.07 12.3 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CbiA PF01656.18 ETO08540.1 - 0.051 12.9 0.2 0.27 10.5 0.1 2.2 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain FtsK_SpoIIIE PF01580.13 ETO08540.1 - 0.064 12.7 0.2 2.3 7.6 0.1 2.4 2 1 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.1 ETO08540.1 - 0.14 11.6 0.2 5.8 6.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain ResIII PF04851.10 ETO08540.1 - 0.19 11.5 2.1 1.9 8.2 1.4 2.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit RRM_1 PF00076.17 ETO08544.1 - 1.1e-13 50.5 0.1 2.2e-05 23.9 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO08544.1 - 5.7e-12 45.4 0.1 7.1e-07 29.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO08544.1 - 0.00071 19.3 0.1 0.0056 16.5 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.13 ETO08544.1 - 0.0048 15.9 4.6 0.011 14.8 3.2 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_3 PF08777.6 ETO08544.1 - 0.052 13.3 0.5 1.2 9.0 0.1 3.1 2 1 0 2 2 2 0 RNA binding motif Nup35_RRM_2 PF14605.1 ETO08544.1 - 0.089 12.5 0.0 0.63 9.8 0.0 2.2 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif tify PF06200.9 ETO08547.1 - 0.16 11.2 0.0 7.3 5.9 0.0 2.6 2 0 0 2 2 2 0 tify domain SH3_1 PF00018.23 ETO08549.1 - 0.0068 15.7 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain V-SNARE_C PF12352.3 ETO08549.1 - 0.053 13.5 1.6 1 9.4 0.1 3.1 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus Coat_F PF07875.7 ETO08549.1 - 0.14 12.3 0.7 16 5.7 0.1 2.3 2 0 0 2 2 2 0 Coat F domain DUF4537 PF15057.1 ETO08550.1 - 1e-05 25.2 0.1 6.6e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4537) 53-BP1_Tudor PF09038.5 ETO08550.1 - 0.0012 18.6 0.0 0.0042 16.8 0.0 1.9 1 0 0 1 1 1 1 Tumour suppressor p53-binding protein-1 Tudor SMN PF06003.7 ETO08550.1 - 0.014 14.5 0.1 0.014 14.5 0.0 2.7 4 0 0 4 4 4 0 Survival motor neuron protein (SMN) E_Pc_C PF06752.7 ETO08550.1 - 0.37 10.2 13.7 0.046 13.2 3.8 2.3 2 0 0 2 2 2 0 Enhancer of Polycomb C-terminus LMBR1 PF04791.11 ETO08550.1 - 1.9 6.9 6.9 0.23 10.0 0.4 2.0 2 0 0 2 2 2 0 LMBR1-like membrane protein AAA_21 PF13304.1 ETO08551.1 - 7.6e-06 26.0 0.0 1.3e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF4162 PF13732.1 ETO08551.1 - 0.0027 18.2 0.1 0.0041 17.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) 7TM_GPCR_Sri PF10327.4 ETO08551.1 - 0.032 13.2 0.0 0.056 12.3 0.0 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri SbcCD_C PF13558.1 ETO08551.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Zip PF02535.17 ETO08552.1 - 1.7e-38 132.4 18.2 2.5e-38 131.8 12.6 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter Macoilin PF09726.4 ETO08552.1 - 7 4.7 8.9 8.2 4.5 6.2 1.1 1 0 0 1 1 1 0 Transmembrane protein IncA PF04156.9 ETO08553.1 - 8.2 5.9 13.3 5.8 6.4 3.6 2.8 2 0 0 2 2 2 0 IncA protein Endonuc_subdom PF09062.5 ETO08554.1 - 0.078 13.7 4.8 0.35 11.6 0.1 3.3 2 1 1 3 3 3 0 PI-PfuI Endonuclease subdomain Kelch_6 PF13964.1 ETO08555.1 - 0.0019 18.3 2.4 0.92 9.7 0.1 4.2 6 0 0 6 6 6 2 Kelch motif Kelch_5 PF13854.1 ETO08555.1 - 0.28 11.1 2.5 31 4.6 0.0 4.2 5 0 0 5 5 5 0 Kelch motif DNA_pol_B PF00136.16 ETO08556.1 - 1.8e-78 264.4 2.9 2.3e-78 264.0 2.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 ETO08556.1 - 7.4e-30 103.6 4.1 1.8e-29 102.4 2.9 1.6 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger zinc_ribbon_5 PF13719.1 ETO08556.1 - 0.023 14.2 0.1 0.055 13.0 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 ETO08556.1 - 0.058 13.0 0.2 0.15 11.7 0.2 1.7 1 0 0 1 1 1 0 zinc-ribbon domain Wzy_C PF04932.10 ETO08556.1 - 0.065 13.0 0.1 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 O-Antigen ligase DNA_pol_B_exo1 PF03104.14 ETO08557.1 - 6.1e-18 64.7 0.5 1.2e-17 63.7 0.4 1.5 1 1 0 1 1 1 1 DNA polymerase family B, exonuclease domain WD40 PF00400.27 ETO08558.1 - 4.2e-49 162.7 6.5 3.1e-10 39.5 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO08558.1 - 8.8e-08 32.0 0.2 2.9e-05 23.8 0.0 2.7 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.4 ETO08558.1 - 0.00031 20.2 0.0 0.0013 18.1 0.0 1.8 2 0 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.3 ETO08558.1 - 0.00078 17.6 4.4 4.9 5.1 0.0 4.7 2 2 2 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO08558.1 - 0.0029 16.4 9.1 0.87 8.2 0.4 4.1 1 1 4 5 5 5 3 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO08558.1 - 0.0043 15.3 0.1 3.6 5.7 0.0 2.7 1 1 0 2 2 2 1 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO08558.1 - 0.0049 16.0 0.7 4 6.4 0.0 4.1 1 1 4 5 5 5 1 Neuroblastoma-amplified sequence, N terminal DPPIV_N PF00930.16 ETO08558.1 - 0.0084 14.7 0.1 2.8 6.4 0.0 3.1 2 1 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.7 ETO08558.1 - 2.5 7.8 7.4 11 5.7 0.0 3.7 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat WxL PF13731.1 ETO08559.1 - 0.0027 17.5 3.4 0.0038 17.0 2.3 1.3 1 0 0 1 1 1 1 WxL domain surface cell wall-binding CobT PF06213.7 ETO08559.1 - 0.011 14.8 4.9 0.015 14.4 3.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Menin PF05053.8 ETO08559.1 - 0.066 11.3 2.3 0.082 11.0 1.6 1.3 1 0 0 1 1 1 0 Menin Neur_chan_memb PF02932.11 ETO08559.1 - 0.15 11.9 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Secretin_N_2 PF07655.8 ETO08559.1 - 0.21 11.9 23.9 0.41 11.0 16.6 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain EST1 PF10374.4 ETO08559.1 - 0.42 10.6 3.8 29 4.6 2.8 2.2 1 1 1 2 2 2 0 Telomerase activating protein Est1 DUF912 PF06024.7 ETO08559.1 - 3.5 7.7 11.1 6.2 6.9 7.7 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Tetraspannin PF00335.15 ETO08559.1 - 7.8 5.7 6.5 10 5.3 4.5 1.2 1 0 0 1 1 1 0 Tetraspanin family MFS_2 PF13347.1 ETO08560.1 - 3e-05 22.6 0.0 3e-05 22.6 0.0 3.8 3 2 1 4 4 4 1 MFS/sugar transport protein Ank_2 PF12796.2 ETO08561.1 - 4.3e-29 100.6 15.4 7e-14 51.9 0.1 4.9 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO08561.1 - 4.3e-25 87.6 6.1 1.5e-06 28.5 0.0 6.5 3 3 3 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 ETO08561.1 - 2.3e-22 77.5 5.0 0.00018 21.1 0.0 7.4 7 1 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.1 ETO08561.1 - 1.4e-19 69.6 13.5 7.3e-07 29.2 0.1 7.8 5 2 3 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO08561.1 - 7.9e-19 65.8 4.2 0.00025 20.9 0.0 8.0 7 1 0 7 7 7 4 Ankyrin repeat Propep_M14 PF02244.11 ETO08561.1 - 0.047 13.3 0.1 0.74 9.5 0.0 2.4 2 0 0 2 2 2 0 Carboxypeptidase activation peptide FRD2 PF03197.8 ETO08561.1 - 0.11 13.0 3.5 0.55 10.8 0.1 2.9 3 0 0 3 3 3 0 Bacteriophage FRD2 protein Glyco_transf_8 PF01501.15 ETO08562.1 - 7.8e-13 48.3 4.0 2.7e-12 46.5 2.8 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 8 Secretin_N_2 PF07655.8 ETO08563.1 - 1.1 9.6 14.1 2.7 8.4 9.8 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain ATP-grasp_4 PF13535.1 ETO08564.1 - 1e-10 41.6 0.0 2e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 ETO08564.1 - 1.4e-05 23.9 0.0 2.2e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 ETO08564.1 - 0.0035 16.6 0.0 0.0074 15.6 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain NOA36 PF06524.7 ETO08564.1 - 0.04 13.1 8.7 0.1 11.8 6.0 1.6 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.8 ETO08564.1 - 0.16 11.5 4.8 0.47 10.0 3.3 1.8 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.4 ETO08564.1 - 4 6.0 20.5 0.11 11.1 9.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 ETO08564.1 - 7.4 6.0 13.5 19 4.7 9.4 1.6 1 0 0 1 1 1 0 Nucleoplasmin CAP_N PF01213.14 ETO08565.1 - 0.44 9.7 10.1 16 4.6 0.0 2.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 ETO08565.1 - 4.7 6.5 8.5 1.1 8.5 3.7 1.5 2 0 0 2 2 2 0 Mitochondrial fission regulator C2 PF00168.25 ETO08567.1 - 7.6e-10 38.5 0.1 1.7e-09 37.3 0.1 1.7 1 0 0 1 1 1 1 C2 domain WD40 PF00400.27 ETO08569.1 - 3.4e-13 48.8 0.3 1.2e-05 25.0 0.1 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat CDC27 PF09507.5 ETO08570.1 - 1.8 7.7 40.1 2 7.5 27.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RA PF00788.18 ETO08571.1 - 0.031 14.7 0.2 0.054 13.9 0.1 1.4 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain RBD PF02196.10 ETO08571.1 - 0.033 13.9 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Raf-like Ras-binding domain FimP PF09766.4 ETO08571.1 - 0.037 13.0 8.9 0.057 12.4 6.1 1.4 1 0 0 1 1 1 0 Fms-interacting protein Menin PF05053.8 ETO08571.1 - 0.091 10.9 7.0 0.12 10.5 4.9 1.4 1 0 0 1 1 1 0 Menin DUF2457 PF10446.4 ETO08571.1 - 0.12 11.0 12.3 0.21 10.2 6.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Utp14 PF04615.8 ETO08571.1 - 4.3 5.3 17.9 5.6 5.0 12.4 1.1 1 0 0 1 1 1 0 Utp14 protein Vps51 PF08700.6 ETO08572.1 - 0.006 16.3 2.9 0.045 13.6 2.0 2.3 1 1 0 1 1 1 1 Vps51/Vps67 SusD-like_3 PF14322.1 ETO08572.1 - 0.021 14.8 0.2 0.037 14.0 0.1 1.4 1 0 0 1 1 1 0 Starch-binding associating with outer membrane EF-hand_6 PF13405.1 ETO08572.1 - 0.045 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.1 ETO08572.1 - 0.054 13.6 0.4 0.13 12.3 0.3 1.6 1 1 0 1 1 1 0 EF-hand domain pair ALMT PF11744.3 ETO08572.1 - 2.9 6.4 5.1 3 6.4 3.0 1.4 1 1 0 1 1 1 0 Aluminium activated malate transporter Hydrolase_3 PF08282.7 ETO08572.1 - 8 5.9 10.7 0.41 10.1 2.4 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase HeLo PF14479.1 ETO08573.1 - 0.0071 16.1 1.3 0.0071 16.1 0.9 3.1 3 1 0 3 3 3 1 Prion-inhibition and propagation BPL_LplA_LipB PF03099.14 ETO08574.1 - 2.5e-12 46.9 0.2 1.6e-11 44.3 0.1 2.3 2 1 0 2 2 2 1 Biotin/lipoate A/B protein ligase family Pkinase PF00069.20 ETO08575.1 - 4.6e-53 180.0 0.1 6.7e-53 179.4 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO08575.1 - 1.3e-23 83.4 0.0 1.9e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO08575.1 - 5.9e-05 22.1 0.0 0.0001 21.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETO08575.1 - 0.021 14.5 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ndufs5 PF10200.4 ETO08575.1 - 1.6 8.7 5.9 1.6 8.7 0.1 3.2 3 1 1 4 4 4 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa cNMP_binding PF00027.24 ETO08576.1 - 3.8e-17 61.8 0.1 9.8e-17 60.5 0.0 1.7 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain YscO PF07321.7 ETO08578.1 - 0.0042 16.9 1.1 0.0058 16.4 0.8 1.1 1 0 0 1 1 1 1 Type III secretion protein YscO Baculo_11_kDa PF06143.6 ETO08579.1 - 2.9 7.3 6.0 2 7.8 1.1 2.6 2 0 0 2 2 2 0 Baculovirus 11 kDa family TPMT PF05724.6 ETO08581.1 - 1.1e-07 31.4 0.4 5.4e-05 22.7 0.1 2.5 1 1 1 2 2 2 2 Thiopurine S-methyltransferase (TPMT) Malic_M PF03949.10 ETO08582.1 - 4.1e-25 88.7 0.0 4.7e-25 88.6 0.0 1.0 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain TPMT PF05724.6 ETO08583.1 - 5.4e-10 39.0 0.2 8.8e-09 35.1 0.0 2.3 2 1 1 3 3 3 1 Thiopurine S-methyltransferase (TPMT) AIP3 PF03915.8 ETO08583.1 - 0.036 12.9 0.1 0.047 12.5 0.1 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Metallophos PF00149.23 ETO08585.1 - 7.9e-32 110.2 0.0 5.9e-31 107.4 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase malic PF00390.14 ETO08586.1 - 1.3e-10 41.1 0.0 1.9e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain malic PF00390.14 ETO08587.1 - 4.7e-34 117.5 0.0 6.1e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain NatB_MDM20 PF09797.4 ETO08589.1 - 4.1e-25 88.2 0.4 7.8e-25 87.3 0.3 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit PQ-loop PF04193.9 ETO08591.1 - 0.00012 21.5 2.3 0.00026 20.4 1.6 1.7 1 1 0 1 1 1 1 PQ loop repeat EF-hand_7 PF13499.1 ETO08593.1 - 1.1e-05 25.4 3.2 0.0002 21.4 0.9 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO08593.1 - 2.2e-05 23.9 4.6 0.25 11.3 0.0 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 ETO08593.1 - 0.00012 21.5 0.8 0.0023 17.4 0.2 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 ETO08593.1 - 0.00038 19.6 4.3 0.014 14.6 0.0 3.8 4 0 0 4 4 4 1 EF hand EF-hand_1 PF00036.27 ETO08593.1 - 0.0013 17.9 7.6 0.0048 16.1 0.0 3.8 5 0 0 5 5 5 1 EF hand Nop14 PF04147.7 ETO08594.1 - 2.2e-05 22.6 33.7 2.8e-05 22.2 23.4 1.3 1 0 0 1 1 1 1 Nop14-like family Zip PF02535.17 ETO08594.1 - 0.045 12.7 3.2 0.067 12.1 2.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SGT1 PF07093.6 ETO08594.1 - 0.14 10.5 27.7 0.16 10.2 19.2 1.2 1 0 0 1 1 1 0 SGT1 protein Astro_capsid PF03115.9 ETO08594.1 - 0.79 7.9 12.2 0.79 7.9 8.4 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF1510 PF07423.6 ETO08594.1 - 1.2 8.4 38.6 0.026 13.9 21.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) CENP-T PF15511.1 ETO08594.1 - 1.9 7.6 28.8 3.2 6.8 20.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CDC45 PF02724.9 ETO08594.1 - 2.6 5.9 36.3 4.3 5.2 25.1 1.3 1 0 0 1 1 1 0 CDC45-like protein HMG_box PF00505.14 ETO08595.1 - 1.5 9.1 26.8 0.36 11.1 0.9 4.5 3 2 0 3 3 3 0 HMG (high mobility group) box Peptidase_S49_N PF08496.5 ETO08595.1 - 6.6 6.5 14.9 0.14 11.8 4.3 2.3 2 1 0 2 2 2 0 Peptidase family S49 N-terminal Ku_PK_bind PF08785.6 ETO08596.1 - 0.047 13.5 0.4 0.081 12.8 0.3 1.3 1 0 0 1 1 1 0 Ku C terminal domain like Cyt-b5 PF00173.23 ETO08597.1 - 3.1e-21 74.9 0.0 5.4e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Senescence_reg PF04520.8 ETO08597.1 - 0.0014 19.1 0.7 0.0014 19.1 0.5 1.1 1 0 0 1 1 1 1 Senescence regulator Ycf1 PF05758.7 ETO08597.1 - 0.12 10.0 11.0 0.14 9.8 7.7 1.0 1 0 0 1 1 1 0 Ycf1 DDHD PF02862.12 ETO08597.1 - 0.34 10.6 8.4 0.39 10.4 5.8 1.1 1 0 0 1 1 1 0 DDHD domain Zip PF02535.17 ETO08597.1 - 0.77 8.7 4.1 0.82 8.6 2.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter YtxH PF12732.2 ETO08597.1 - 1.4 9.3 5.4 2.8 8.3 3.7 1.5 1 0 0 1 1 1 0 YtxH-like protein DUF3474 PF11960.3 ETO08597.1 - 2.3 8.2 7.6 1.3 9.0 3.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) Spore_coat_CotO PF14153.1 ETO08597.1 - 2.7 7.4 16.4 3.9 6.8 11.4 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Vfa1 PF08432.5 ETO08597.1 - 4.3 7.3 21.4 6.2 6.8 14.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Presenilin PF01080.12 ETO08597.1 - 4.8 5.8 8.2 5.7 5.6 5.6 1.2 1 0 0 1 1 1 0 Presenilin DUF1510 PF07423.6 ETO08597.1 - 4.9 6.4 22.3 6.4 6.0 15.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Phyto_Pns9_10 PF05878.6 ETO08597.1 - 8.1 5.3 8.0 10 5.0 5.6 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 DUF3399 PF11879.3 ETO08600.1 - 0.065 13.4 0.3 0.17 12.1 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3399) PYRIN PF02758.11 ETO08601.1 - 0.066 12.9 0.3 0.2 11.3 0.1 1.8 2 0 0 2 2 2 0 PAAD/DAPIN/Pyrin domain AAA PF00004.24 ETO08602.1 - 1e-12 48.3 0.1 2.5e-05 24.4 0.0 4.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETO08602.1 - 3.6e-08 33.6 0.0 0.027 14.6 0.0 4.0 4 1 0 4 4 3 2 AAA domain AAA_5 PF07728.9 ETO08602.1 - 7.1e-07 29.0 0.3 0.011 15.4 0.0 3.7 4 2 0 4 4 4 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 ETO08602.1 - 6e-06 25.7 1.4 0.024 14.0 0.0 4.1 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_16 PF13191.1 ETO08602.1 - 0.00016 21.6 0.1 0.1 12.5 0.0 3.6 3 1 0 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 ETO08602.1 - 0.00034 20.5 2.5 0.022 14.6 0.0 4.3 4 0 0 4 4 4 1 AAA domain ABC_tran PF00005.22 ETO08602.1 - 0.0016 18.7 0.3 0.014 15.7 0.0 2.8 3 0 0 3 3 3 1 ABC transporter Sigma54_activ_2 PF14532.1 ETO08602.1 - 0.002 18.1 0.7 0.73 9.8 0.0 3.7 3 1 0 3 3 3 1 Sigma-54 interaction domain NACHT PF05729.7 ETO08602.1 - 0.0033 17.1 0.3 0.97 9.0 0.0 3.6 3 0 0 3 3 3 1 NACHT domain DUF815 PF05673.8 ETO08602.1 - 0.0039 16.1 0.1 0.053 12.4 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF815) DUF258 PF03193.11 ETO08602.1 - 0.0083 15.3 2.2 0.0087 15.2 0.0 2.1 3 0 0 3 3 3 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 ETO08602.1 - 0.018 14.5 0.0 0.047 13.1 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.21 ETO08602.1 - 0.05 13.0 0.0 0.84 9.0 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain MCM PF00493.18 ETO08602.1 - 0.056 12.2 3.6 0.85 8.3 0.0 3.4 4 0 0 4 4 4 0 MCM2/3/5 family PDGF_N PF04692.8 ETO08602.1 - 0.057 13.9 0.1 5.3 7.5 0.0 2.8 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region AAA_19 PF13245.1 ETO08602.1 - 0.16 11.7 0.2 16 5.3 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain DUF349 PF03993.7 ETO08604.1 - 0.62 10.2 4.4 0.67 10.1 2.3 1.7 1 1 0 1 1 1 0 Domain of Unknown Function (DUF349) BPL_N PF09825.4 ETO08604.1 - 9 4.9 9.0 11 4.6 6.2 1.0 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Sugar_tr PF00083.19 ETO08605.1 - 2.4e-17 62.6 10.5 3.2e-17 62.2 7.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETO08605.1 - 1.6e-14 53.4 12.7 1.9e-14 53.1 8.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 ETO08605.1 - 1.4e-05 23.5 4.2 1.8e-05 23.1 2.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 ETO08605.1 - 0.079 11.3 13.3 0.24 9.7 8.3 2.2 1 1 1 2 2 2 0 MFS/sugar transport protein ECH PF00378.15 ETO08607.1 - 3e-30 105.1 0.0 7.2e-30 103.8 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 ETO08607.1 - 0.0083 15.9 0.2 6 6.6 0.0 2.7 3 0 0 3 3 3 2 Peptidase family S49 DUF2247 PF10004.4 ETO08607.1 - 0.075 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) zf-TRAF PF02176.13 ETO08608.1 - 6.2e-06 26.5 3.1 6.2e-06 26.5 2.2 2.9 3 0 0 3 3 3 1 TRAF-type zinc finger Herpes_BLRF2 PF05812.7 ETO08608.1 - 0.02 14.6 5.0 0.039 13.7 2.9 1.9 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein Kelch_6 PF13964.1 ETO08609.1 - 3.3e-06 27.0 1.7 0.087 13.0 0.1 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 ETO08609.1 - 0.00038 20.0 1.8 1.5 8.7 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO08609.1 - 0.00057 19.3 6.0 0.0091 15.5 0.2 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETO08609.1 - 0.0009 18.9 0.0 0.74 9.6 0.0 3.4 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO08609.1 - 0.017 15.2 0.0 2.8 8.2 0.0 3.3 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO08609.1 - 0.089 12.7 0.9 66 3.6 0.0 4.0 4 0 0 4 4 4 0 Kelch motif Methyltransf_FA PF12248.3 ETO08609.1 - 0.098 12.6 2.2 1.9 8.5 0.0 3.4 2 2 0 2 2 2 0 Farnesoic acid 0-methyl transferase B56 PF01603.15 ETO08611.1 - 7.9e-137 456.1 15.7 1.7e-136 455.0 10.9 1.5 1 1 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) RXT2_N PF08595.6 ETO08611.1 - 0.058 13.1 0.7 0.21 11.3 0.0 2.2 3 0 0 3 3 3 0 RXT2-like, N-terminal TOM13 PF08219.6 ETO08612.1 - 0.39 10.5 2.1 0.73 9.6 0.3 2.3 2 0 0 2 2 2 0 Outer membrane protein TOM13 Zip PF02535.17 ETO08612.1 - 0.77 8.7 7.7 1.1 8.1 5.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Robl_LC7 PF03259.12 ETO08614.1 - 3.4e-06 26.5 0.0 9e-05 21.9 0.0 2.1 1 1 0 1 1 1 1 Roadblock/LC7 domain Cgr1 PF03879.9 ETO08618.1 - 0.05 13.7 2.3 0.05 13.7 1.6 3.3 2 1 0 2 2 2 0 Cgr1 family Mitofilin PF09731.4 ETO08618.1 - 0.59 8.7 27.4 0.71 8.4 19.0 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein LrgA PF03788.9 ETO08619.1 - 0.15 11.7 3.1 0.26 10.9 2.2 1.3 1 0 0 1 1 1 0 LrgA family DUF4573 PF15140.1 ETO08620.1 - 0.014 14.9 12.7 0.08 12.5 1.9 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4573) CesA PF11439.3 ETO08620.1 - 0.13 12.2 0.5 2.3 8.1 0.0 2.7 2 1 1 3 3 3 0 Type III secretion system filament chaperone CesA ATP-grasp_5 PF13549.1 ETO08620.1 - 0.15 11.2 0.3 3.3 6.8 0.0 2.5 2 1 1 3 3 3 0 ATP-grasp domain Retinal PF15449.1 ETO08620.1 - 0.19 9.3 37.3 0.38 8.3 14.9 2.0 1 1 1 2 2 2 0 Retinal protein WD40 PF00400.27 ETO08621.1 - 0.00057 19.6 1.4 0.011 15.6 0.0 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO08621.1 - 0.0015 16.7 0.0 0.0021 16.3 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Peptidase_S76 PF13611.1 ETO08621.1 - 0.085 12.9 2.8 0.16 12.0 2.0 1.5 1 0 0 1 1 1 0 Serine peptidase of plant viral polyprotein, P1 LRR_4 PF12799.2 ETO08623.1 - 3.6e-08 32.8 18.7 1.7e-05 24.3 2.7 4.8 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETO08623.1 - 5.6e-06 25.6 23.3 0.32 11.1 0.1 8.2 10 0 0 10 10 10 4 Leucine Rich Repeat LRR_8 PF13855.1 ETO08623.1 - 9.9e-05 22.0 20.5 0.00049 19.7 2.7 4.2 3 1 1 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 ETO08623.1 - 0.0038 17.1 14.6 0.47 10.6 0.4 5.6 6 0 0 6 6 6 3 Leucine Rich repeat LRR_7 PF13504.1 ETO08623.1 - 0.1 12.8 11.8 43 4.9 0.0 6.3 6 0 0 6 6 6 0 Leucine rich repeat Pkinase PF00069.20 ETO08624.1 - 2.6e-35 121.8 0.3 6.4e-35 120.5 0.1 1.7 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO08624.1 - 1.5e-08 34.0 0.0 6.1e-08 32.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 ETO08624.1 - 0.012 14.9 0.1 0.03 13.6 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL zf-RVT PF13966.1 ETO08625.1 - 0.018 15.3 0.5 0.045 14.0 0.0 1.9 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase GCR1_C PF12550.3 ETO08625.1 - 0.88 9.4 4.6 3.1 7.7 0.7 2.5 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes Aldo_ket_red PF00248.16 ETO08626.1 - 1.9e-34 118.8 0.0 2.7e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.20 ETO08627.1 - 5.8e-39 133.7 0.0 8.2e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO08627.1 - 3.6e-20 72.1 0.0 2.2e-19 69.5 0.0 1.9 1 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 ETO08627.1 - 1.8e-07 30.4 0.1 3e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 ETO08627.1 - 0.00066 19.3 0.1 0.0015 18.1 0.1 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 ETO08627.1 - 0.041 13.6 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4611 PF15387.1 ETO08628.1 - 0.19 11.9 4.9 0.36 10.9 3.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) FAM176 PF14851.1 ETO08628.1 - 7.5 6.2 9.9 4.2 7.0 3.9 2.3 2 0 0 2 2 2 0 FAM176 family AAA PF00004.24 ETO08630.1 - 2.5e-10 40.6 0.0 3.7e-06 27.1 0.0 3.1 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETO08630.1 - 1.1e-06 28.7 0.0 0.0051 16.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.9 ETO08630.1 - 1.5e-06 28.0 0.0 0.002 17.8 0.0 3.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 ETO08630.1 - 0.00012 21.9 0.9 0.0014 18.5 0.0 3.0 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 ETO08630.1 - 0.00015 21.7 0.5 0.061 13.3 0.1 2.9 3 1 0 3 3 3 1 AAA ATPase domain DUF815 PF05673.8 ETO08630.1 - 0.00072 18.5 0.1 0.0026 16.7 0.0 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 ETO08630.1 - 0.00092 19.5 2.9 0.0022 18.3 0.0 2.9 4 0 0 4 4 4 1 ABC transporter IstB_IS21 PF01695.12 ETO08630.1 - 0.00092 18.6 0.0 0.012 14.9 0.0 2.7 3 0 0 3 3 3 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 ETO08630.1 - 0.0015 18.5 0.6 0.14 12.2 0.0 3.6 4 0 0 4 4 4 1 Sigma-54 interaction domain PduV-EutP PF10662.4 ETO08630.1 - 0.0052 16.2 0.1 0.019 14.4 0.0 1.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Peptidase_S49_N PF08496.5 ETO08630.1 - 0.0075 16.0 3.7 0.018 14.8 2.5 1.6 1 0 0 1 1 1 1 Peptidase family S49 N-terminal Zeta_toxin PF06414.7 ETO08630.1 - 0.0079 15.3 0.0 0.028 13.5 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.7 ETO08630.1 - 0.0081 15.8 0.3 0.73 9.4 0.0 3.7 4 0 0 4 4 4 1 NACHT domain MCM PF00493.18 ETO08630.1 - 0.013 14.3 0.4 1.4 7.6 0.0 3.0 3 1 0 3 3 3 0 MCM2/3/5 family DUF258 PF03193.11 ETO08630.1 - 0.014 14.5 0.0 0.033 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 ETO08630.1 - 0.015 15.5 2.6 0.096 12.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain Sigma54_activat PF00158.21 ETO08630.1 - 0.027 13.9 0.1 0.82 9.1 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain Neur_chan_memb PF02932.11 ETO08630.1 - 0.028 14.3 0.1 0.037 13.9 0.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AAA_19 PF13245.1 ETO08630.1 - 0.031 14.0 0.1 5.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain T2SE PF00437.15 ETO08630.1 - 0.045 12.6 0.3 1 8.2 0.1 2.4 2 1 0 2 2 2 0 Type II/IV secretion system protein UPF0079 PF02367.12 ETO08630.1 - 0.081 12.5 0.1 0.26 10.9 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 ETO08630.1 - 0.13 11.9 0.1 0.13 11.9 0.0 2.6 2 1 1 3 3 3 0 Archaeal ATPase Mg_chelatase PF01078.16 ETO08630.1 - 0.16 11.1 0.1 11 5.1 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.1 ETO08630.1 - 1.7 8.9 17.1 4.2 7.6 3.7 3.0 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.9 ETO08631.1 - 0.0034 17.1 0.0 0.0068 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF1644 PF07800.7 ETO08631.1 - 0.034 14.0 0.1 0.065 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) AAA_9 PF12781.2 ETO08631.1 - 0.06 12.1 0.0 0.099 11.4 0.0 1.4 1 0 0 1 1 1 0 ATP-binding dynein motor region D5 Rubrerythrin PF02915.12 ETO08633.1 - 0.34 11.2 0.0 0.34 11.2 0.0 2.8 4 0 0 4 4 4 0 Rubrerythrin DUF641 PF04859.7 ETO08634.1 - 0.0065 16.2 3.3 0.017 14.8 0.0 2.6 3 0 0 3 3 3 1 Plant protein of unknown function (DUF641) SlyX PF04102.7 ETO08634.1 - 0.034 14.5 4.9 0.13 12.6 0.1 2.4 2 0 0 2 2 2 0 SlyX IncA PF04156.9 ETO08634.1 - 0.034 13.7 2.0 0.074 12.6 0.5 1.9 1 1 1 2 2 2 0 IncA protein Bap31 PF05529.7 ETO08634.1 - 0.034 13.5 1.9 0.065 12.6 1.3 1.5 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Spc24 PF08286.6 ETO08634.1 - 0.087 12.5 7.7 1.2 8.8 0.8 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 D5_N PF08706.6 ETO08634.1 - 0.087 12.9 1.7 1.6 8.8 1.2 2.2 1 1 0 1 1 1 0 D5 N terminal like TMF_TATA_bd PF12325.3 ETO08634.1 - 0.092 12.4 6.2 0.34 10.6 0.0 2.8 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF948 PF06103.6 ETO08634.1 - 0.49 10.2 5.6 0.2 11.5 0.4 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Phage_GP20 PF06810.6 ETO08634.1 - 0.57 9.6 8.0 0.094 12.1 0.7 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 Uso1_p115_C PF04871.8 ETO08634.1 - 5.9 6.8 10.0 0.58 10.0 0.1 2.4 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region DivIC PF04977.10 ETO08634.1 - 6.7 6.2 14.3 1.4 8.4 0.8 3.9 3 1 1 4 4 4 0 Septum formation initiator WD40 PF00400.27 ETO08635.1 - 1e-24 85.4 0.1 1.5e-08 34.1 0.0 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Ubiquitin_3 PF14836.1 ETO08635.1 - 0.039 13.6 0.1 0.13 11.9 0.0 1.8 1 1 1 2 2 2 0 Ubiquitin-like domain Nup160 PF11715.3 ETO08635.1 - 0.04 12.0 0.2 1.5 6.8 0.0 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO08635.1 - 0.068 12.8 0.1 0.12 12.0 0.0 1.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF1651 PF07864.6 ETO08635.1 - 0.13 12.3 3.1 13 5.9 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1651) Myb_DNA-bind_6 PF13921.1 ETO08636.1 - 0.11 12.6 1.1 1.4 9.1 0.2 2.1 1 1 1 2 2 2 0 Myb-like DNA-binding domain Pex16 PF08610.5 ETO08639.1 - 1.5 7.7 7.7 0.43 9.5 3.5 1.4 1 1 1 2 2 2 0 Peroxisomal membrane protein (Pex16) Ets PF00178.17 ETO08640.1 - 0.03 14.4 0.1 0.087 12.9 0.1 1.7 1 0 0 1 1 1 0 Ets-domain Vac14_Fab1_bd PF12755.2 ETO08640.1 - 0.22 11.9 2.2 11 6.4 0.5 2.2 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region WD40 PF00400.27 ETO08641.1 - 6.4e-62 203.3 30.1 1.8e-12 46.5 0.1 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat zf-TRAF PF02176.13 ETO08641.1 - 4.6e-05 23.7 2.0 4.6e-05 23.7 1.4 2.7 2 1 0 2 2 2 1 TRAF-type zinc finger DUF869 PF05911.6 ETO08641.1 - 0.0026 16.0 12.4 0.0037 15.5 8.6 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) CENP-Q PF13094.1 ETO08641.1 - 0.15 12.0 14.8 0.022 14.7 5.5 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4407 PF14362.1 ETO08641.1 - 0.26 10.2 16.3 0.4 9.5 11.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4239 PF14023.1 ETO08641.1 - 0.8 9.0 2.9 1.4 8.2 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Spc7 PF08317.6 ETO08641.1 - 0.87 8.1 17.2 1.5 7.3 11.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.3 ETO08641.1 - 1.7 8.3 16.3 22 4.7 10.4 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF641 PF04859.7 ETO08641.1 - 2.5 7.8 13.6 13 5.5 5.5 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) V_ATPase_I PF01496.14 ETO08641.1 - 7.8 4.2 10.9 11 3.6 7.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PPR_2 PF13041.1 ETO08642.1 - 2.5e-05 24.1 0.0 5.7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 PPR repeat family PPR PF01535.15 ETO08642.1 - 0.00029 20.5 0.0 0.0012 18.6 0.0 2.1 1 0 0 1 1 1 1 PPR repeat PPR_1 PF12854.2 ETO08642.1 - 0.0017 17.7 0.2 0.0037 16.7 0.2 1.6 1 0 0 1 1 1 1 PPR repeat PPR_3 PF13812.1 ETO08642.1 - 0.12 12.7 0.0 3.2 8.2 0.0 2.9 2 0 0 2 2 2 0 Pentatricopeptide repeat domain SNF2_N PF00176.18 ETO08643.1 - 8.5e-69 231.6 3.8 8.5e-69 231.6 2.6 1.9 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETO08643.1 - 1.8e-12 46.9 0.0 5.6e-12 45.3 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETO08643.1 - 3.7e-05 23.2 0.4 0.04 13.3 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 ETO08643.1 - 0.021 14.6 10.2 0.083 12.7 4.1 3.1 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit CoA_transf_3 PF02515.12 ETO08644.1 - 1.8e-12 46.8 0.0 2.4e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III DUF4105 PF13387.1 ETO08644.1 - 0.094 11.8 0.0 1.1 8.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4105) DUF1967 PF09269.6 ETO08645.1 - 0.066 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) Ring_hydroxyl_A PF00848.14 ETO08646.1 - 4.2e-35 121.2 0.1 9.9e-35 120.0 0.0 1.6 2 0 0 2 2 2 1 Ring hydroxylating alpha subunit (catalytic domain) Myb_DNA-bind_6 PF13921.1 ETO08647.1 - 0.004 17.2 0.3 0.0085 16.1 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 ETO08647.1 - 0.011 15.7 0.2 0.043 13.8 0.2 2.0 1 1 0 1 1 1 0 Myb-like DNA-binding domain PDZ_2 PF13180.1 ETO08647.1 - 0.036 13.9 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 PDZ domain DXP_reductoisom PF02670.11 ETO08647.1 - 0.21 12.1 2.9 5.9 7.4 0.6 2.3 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase SURF2 PF05477.6 ETO08650.1 - 0.15 11.1 4.5 0.26 10.3 3.1 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) MIP-T3 PF10243.4 ETO08651.1 - 0.057 11.8 37.8 0.064 11.7 26.2 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1777 PF08648.7 ETO08651.1 - 0.14 11.8 65.3 0.069 12.8 29.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1777) Merozoite_SPAM PF07133.6 ETO08651.1 - 0.74 9.6 17.2 0.86 9.4 11.9 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Ycf1 PF05758.7 ETO08651.1 - 3.7 5.1 14.7 4.3 4.9 10.2 1.0 1 0 0 1 1 1 0 Ycf1 Raftlin PF15250.1 ETO08651.1 - 6.2 5.2 9.0 7.2 5.0 6.2 1.2 1 0 0 1 1 1 0 Raftlin Neur_chan_memb PF02932.11 ETO08651.1 - 8.8 6.1 5.8 11 5.8 4.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region HSP70 PF00012.15 ETO08652.1 - 8.1e-21 73.5 2.0 2e-20 72.2 0.0 2.0 2 0 0 2 2 2 1 Hsp70 protein DUF3485 PF11984.3 ETO08652.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3485) Proteasom_Rpn13 PF04683.8 ETO08653.1 - 9.2e-12 44.8 0.0 2.7e-11 43.4 0.0 1.9 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor CUE PF02845.11 ETO08653.1 - 4.4e-07 29.2 0.2 0.001 18.5 0.2 2.6 2 0 0 2 2 2 2 CUE domain DMA PF03474.9 ETO08653.1 - 1.5e-05 24.7 0.0 0.011 15.5 0.0 2.4 2 0 0 2 2 2 2 DMRTA motif HTH_8 PF02954.14 ETO08653.1 - 0.08 12.4 0.0 0.5 9.9 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family Mucin PF01456.12 ETO08653.1 - 1.5 8.5 12.0 1.2 8.9 4.8 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF2151 PF10221.4 ETO08654.1 - 0.084 11.0 6.4 0.04 12.0 2.2 1.7 2 0 0 2 2 2 0 Cell cycle and development regulator NapE PF06796.6 ETO08654.1 - 1.2 8.4 0.0 1.2 8.4 0.0 2.3 3 0 0 3 3 3 0 Periplasmic nitrate reductase protein NapE GtrA PF04138.9 ETO08656.1 - 0.0003 20.7 9.0 0.00093 19.1 6.0 1.9 1 1 1 2 2 2 1 GtrA-like protein DUF4229 PF14012.1 ETO08656.1 - 0.0028 17.5 1.7 0.0033 17.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) 2OG-FeII_Oxy_2 PF13532.1 ETO08657.1 - 5.9e-09 36.0 1.3 2.9e-07 30.5 0.1 2.3 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily DUF1947 PF09183.5 ETO08657.1 - 0.076 12.7 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) DUF3461 PF11944.3 ETO08658.1 - 0.078 12.8 6.0 0.15 11.9 3.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3461) Occludin_ELL PF07303.8 ETO08658.1 - 0.16 12.7 5.8 0.097 13.4 2.1 2.0 1 1 0 1 1 1 0 Occludin homology domain AAA_23 PF13476.1 ETO08658.1 - 0.5 10.6 12.1 0.65 10.2 8.4 1.2 1 0 0 1 1 1 0 AAA domain NYD-SP28_assoc PF14775.1 ETO08658.1 - 0.76 9.5 5.4 1.7 8.4 3.8 1.7 1 0 0 1 1 1 0 Sperm tail C-terminal domain Syntaxin-6_N PF09177.6 ETO08658.1 - 0.85 10.0 6.6 2.3 8.6 4.6 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal CDC37_N PF03234.9 ETO08658.1 - 0.92 9.8 12.4 0.056 13.7 4.2 1.9 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding bZIP_2 PF07716.10 ETO08658.1 - 1.4 8.8 8.8 1.7 8.4 5.4 1.8 1 1 0 1 1 1 0 Basic region leucine zipper DDHD PF02862.12 ETO08658.1 - 2.4 7.9 7.2 3 7.5 4.4 1.6 1 1 0 1 1 1 0 DDHD domain AKNA PF12443.3 ETO08658.1 - 5.1 7.1 12.0 1.7 8.6 4.3 2.2 1 1 1 2 2 2 0 AT-hook-containing transcription factor Med21 PF11221.3 ETO08659.1 - 9.6e-07 28.8 8.9 1.1e-06 28.7 6.1 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex HR1 PF02185.11 ETO08659.1 - 0.022 14.5 3.8 0.053 13.2 2.6 1.7 1 0 0 1 1 1 0 Hr1 repeat DUF4527 PF15030.1 ETO08659.1 - 0.096 11.9 3.9 0.1 11.8 2.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4527) DUF740 PF05340.7 ETO08659.1 - 0.13 10.6 4.1 0.14 10.5 2.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF740) CpXC PF14353.1 ETO08659.1 - 0.16 11.9 1.3 0.2 11.6 0.9 1.3 1 0 0 1 1 1 0 CpXC protein Epsilon_antitox PF08998.6 ETO08659.1 - 0.2 11.6 2.8 0.28 11.1 1.9 1.3 1 0 0 1 1 1 0 Bacterial epsilon antitoxin SRI PF08236.6 ETO08659.1 - 0.2 11.6 2.5 3.9 7.4 0.1 2.3 1 1 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain Tctex-1 PF03645.8 ETO08659.1 - 0.21 11.4 1.0 3.3 7.6 0.0 2.1 2 0 0 2 2 2 0 Tctex-1 family YgaB PF14182.1 ETO08659.1 - 0.83 9.9 7.7 1.9 8.7 5.4 1.6 1 0 0 1 1 1 0 YgaB-like protein HisKA PF00512.20 ETO08661.1 - 0.093 12.7 0.2 2.8 7.9 0.0 2.4 1 1 1 2 2 2 0 His Kinase A (phospho-acceptor) domain XhlA PF10779.4 ETO08661.1 - 1.7 8.6 8.0 0.51 10.2 3.1 2.0 2 0 0 2 2 2 0 Haemolysin XhlA TPR_11 PF13414.1 ETO08662.1 - 2e-18 65.7 21.8 5.3e-07 29.1 1.3 4.1 2 1 2 4 4 4 4 TPR repeat TPR_2 PF07719.12 ETO08662.1 - 2.6e-16 58.1 17.7 3.5e-05 23.3 0.7 5.7 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO08662.1 - 4e-14 51.5 15.8 6.4e-05 22.3 0.4 5.5 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_17 PF13431.1 ETO08662.1 - 2.2e-11 42.9 16.2 0.00078 19.4 0.1 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO08662.1 - 3.6e-11 42.0 17.2 0.036 13.8 0.3 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 ETO08662.1 - 9e-10 38.7 9.9 0.00011 22.5 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 ETO08662.1 - 1.3e-09 37.8 21.0 0.0039 17.0 2.4 4.5 3 2 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO08662.1 - 1.8e-08 34.7 4.9 0.00017 22.1 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO08662.1 - 2.1e-08 34.0 1.7 0.0035 17.8 0.0 4.6 2 1 3 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO08662.1 - 3.4e-07 30.3 13.8 0.46 11.0 0.2 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 ETO08662.1 - 3.9e-07 30.1 21.6 2.2e-05 24.5 6.4 3.2 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 ETO08662.1 - 6e-06 25.6 8.3 1.5 8.7 0.1 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO08662.1 - 6.2e-06 25.9 4.2 0.078 12.9 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 ETO08662.1 - 0.00012 21.2 7.8 0.24 10.4 1.4 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETO08662.1 - 0.084 12.7 1.6 29 4.6 0.0 3.4 2 1 2 4 4 4 0 Tetratricopeptide repeat TNF PF00229.13 ETO08662.1 - 0.086 12.3 4.7 0.021 14.3 0.9 1.8 2 0 0 2 2 2 0 TNF(Tumour Necrosis Factor) family PCI_Csn8 PF10075.4 ETO08663.1 - 1.3e-16 60.6 0.1 1.5e-16 60.4 0.1 1.0 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 ETO08663.1 - 3.7e-14 52.7 0.1 4.1e-14 52.6 0.0 1.0 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family WD40 PF00400.27 ETO08664.1 - 1.6e-152 490.6 36.7 6.7e-12 44.7 1.4 16.5 15 1 1 16 16 16 15 WD domain, G-beta repeat Nup160 PF11715.3 ETO08664.1 - 1.8e-11 42.9 24.1 1.1 7.2 0.0 11.1 2 2 9 11 11 11 6 Nucleoporin Nup120/160 NACHT PF05729.7 ETO08664.1 - 1.2e-07 31.5 0.0 2.3e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Pentapeptide PF00805.17 ETO08664.1 - 4.7e-06 25.7 1.8 1.1e-05 24.5 1.2 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 ETO08664.1 - 9.3e-06 25.4 1.3 3e-05 23.7 0.9 1.9 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA_22 PF13401.1 ETO08664.1 - 5.6e-05 23.2 0.0 0.00016 21.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETO08664.1 - 8.4e-05 22.8 0.2 0.00048 20.4 0.0 2.5 2 0 0 2 2 1 1 AAA domain Pentapeptide_4 PF13599.1 ETO08664.1 - 0.00014 21.5 0.7 0.0004 20.1 0.5 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) PD40 PF07676.7 ETO08664.1 - 0.00043 19.8 16.7 14 5.4 0.0 7.6 7 1 0 7 7 7 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO08664.1 - 0.0009 17.6 0.9 0.5 8.5 0.0 3.7 3 1 1 4 4 4 2 Cytochrome D1 heme domain AAA_17 PF13207.1 ETO08664.1 - 0.0058 17.4 0.0 0.028 15.2 0.0 2.3 1 0 0 1 1 1 1 AAA domain RelA_SpoT PF04607.12 ETO08664.1 - 0.006 16.5 1.2 0.006 16.5 0.8 2.8 3 0 0 3 3 3 1 Region found in RelA / SpoT proteins DUF258 PF03193.11 ETO08664.1 - 0.01 15.0 0.0 0.024 13.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 ETO08664.1 - 0.026 14.0 0.1 0.23 11.0 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain T2SE PF00437.15 ETO08664.1 - 0.064 12.1 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Resistin PF06954.6 ETO08664.1 - 0.11 12.8 2.2 55 4.1 0.0 5.2 3 1 3 6 6 5 0 Resistin AAA_16 PF13191.1 ETO08664.1 - 0.22 11.5 0.1 1.6 8.7 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain CAP_GLY PF01302.20 ETO08665.1 - 1.4e-15 56.6 0.6 2.2e-15 56.0 0.4 1.3 1 0 0 1 1 1 1 CAP-Gly domain Glycos_transf_2 PF00535.21 ETO08666.1 - 2.4e-34 118.4 0.5 2.4e-34 118.4 0.4 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 ETO08666.1 - 5.2e-15 55.8 0.0 1.2e-14 54.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 AdoHcyase PF05221.12 ETO08666.1 - 0.0061 15.5 0.3 0.0095 14.9 0.2 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase Glyco_tranf_2_4 PF13704.1 ETO08666.1 - 0.014 15.6 0.1 0.043 14.1 0.1 1.8 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.1 ETO08666.1 - 0.1 12.2 0.1 0.21 11.2 0.1 1.4 1 1 0 1 1 1 0 Glycosyl transferase family group 2 DUF3997 PF13162.1 ETO08666.1 - 3 7.7 11.5 0.84 9.4 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3997) Eapp_C PF10238.4 ETO08668.1 - 0.011 15.5 2.9 0.017 15.0 2.0 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein Secretin_N_2 PF07655.8 ETO08668.1 - 0.027 14.8 1.0 0.043 14.1 0.7 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain zf-rbx1 PF12678.2 ETO08670.1 - 4.8e-13 49.0 11.9 7.1e-13 48.4 7.0 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 ETO08670.1 - 1.8e-07 30.8 9.0 1.8e-07 30.8 6.2 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 ETO08670.1 - 0.00019 21.1 14.8 0.00019 21.1 10.2 2.9 3 1 0 3 3 3 1 Ring finger domain ubiquitin PF00240.18 ETO08670.1 - 0.00031 20.0 3.4 0.00054 19.3 1.2 2.2 2 1 0 2 2 2 1 Ubiquitin family zf-C3HC4_2 PF13923.1 ETO08670.1 - 0.002 18.1 9.6 0.008 16.1 6.7 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Terminase_6 PF03237.10 ETO08670.1 - 0.03 13.0 0.0 0.099 11.3 0.0 1.8 2 1 0 2 2 2 0 Terminase-like family zf-RING_5 PF14634.1 ETO08670.1 - 0.091 12.5 15.5 0.48 10.1 10.8 2.3 1 1 0 1 1 1 0 zinc-RING finger domain UN_NPL4 PF11543.3 ETO08670.1 - 0.11 12.7 0.9 6.5 7.1 0.1 2.4 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 zf-C3HC4_3 PF13920.1 ETO08670.1 - 0.48 10.1 16.1 3.8 7.2 11.1 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO08670.1 - 0.59 9.8 15.0 2.6 7.7 10.4 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rad60-SLD PF11976.3 ETO08670.1 - 2.2 8.0 5.5 2.9 7.6 0.8 2.4 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like DUF2773 PF10971.3 ETO08672.1 - 0.098 12.6 1.0 0.3 11.0 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2773) PH_5 PF15405.1 ETO08673.1 - 0.016 15.1 4.4 0.023 14.6 3.1 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain Neur_chan_memb PF02932.11 ETO08673.1 - 0.049 13.5 4.5 0.06 13.2 3.1 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S49_N PF08496.5 ETO08673.1 - 0.1 12.3 7.3 0.13 12.0 5.0 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2217 PF10265.4 ETO08673.1 - 0.13 11.0 2.5 0.14 10.8 1.7 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) BLVR PF06375.6 ETO08673.1 - 0.5 10.1 19.8 0.47 10.2 5.9 2.1 1 1 1 2 2 2 0 Bovine leukaemia virus receptor (BLVR) SPT6_acidic PF14632.1 ETO08673.1 - 0.64 10.2 12.6 0.056 13.6 1.1 2.1 1 1 1 2 2 2 0 Acidic N-terminal SPT6 PTEN_C2 PF10409.4 ETO08674.1 - 2.2e-07 30.6 2.7 8.4e-07 28.7 1.9 2.0 1 1 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DUF4449 PF14613.1 ETO08676.1 - 0.022 14.7 0.9 0.024 14.5 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) ACDC PF14733.1 ETO08676.1 - 0.035 14.2 1.3 0.035 14.2 0.9 2.0 3 0 0 3 3 3 0 AP2-coincident C-terminal Clat_adaptor_s PF01217.15 ETO08676.1 - 0.063 13.0 2.2 0.13 11.9 1.6 1.5 1 1 1 2 2 2 0 Clathrin adaptor complex small chain PTA_PTB PF01515.14 ETO08676.1 - 0.066 12.2 0.5 0.087 11.8 0.3 1.1 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase DNMT1-RFD PF12047.3 ETO08676.1 - 0.069 12.8 0.1 0.12 12.0 0.0 1.6 1 1 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain TPMT PF05724.6 ETO08677.1 - 2.5e-21 76.1 0.0 5.2e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.1 ETO08677.1 - 0.00024 20.7 0.0 0.0081 15.7 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO08677.1 - 0.00047 20.5 0.1 0.015 15.7 0.0 3.3 2 1 2 4 4 4 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO08677.1 - 0.0071 16.9 0.0 0.02 15.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Adenine_glyco PF03352.8 ETO08679.1 - 0.0093 15.4 0.3 0.012 15.1 0.2 1.1 1 0 0 1 1 1 1 Methyladenine glycosylase Enterotoxin_ST PF02048.11 ETO08679.1 - 0.14 12.3 6.5 0.32 11.2 4.5 1.5 1 0 0 1 1 1 0 Heat-stable enterotoxin ST CDK5_activator PF03261.10 ETO08680.1 - 2.4 7.4 7.5 9 5.5 5.3 1.7 1 1 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Peptidase_C97 PF05903.9 ETO08681.1 - 0.00059 19.6 0.2 0.00059 19.6 0.1 2.0 2 0 0 2 2 2 1 PPPDE putative peptidase domain CDC45 PF02724.9 ETO08682.1 - 0.058 11.4 17.6 0.064 11.2 12.2 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 ETO08682.1 - 0.092 12.1 25.3 0.11 11.8 17.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TRAP_alpha PF03896.11 ETO08682.1 - 0.27 10.1 5.2 0.3 10.0 3.6 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit TraV PF09676.5 ETO08682.1 - 0.27 11.9 5.6 0.4 11.4 3.9 1.2 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) Zip PF02535.17 ETO08682.1 - 0.28 10.1 6.2 0.31 10.0 4.3 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.8 ETO08682.1 - 0.29 9.6 19.5 0.34 9.3 13.5 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DHHW PF14286.1 ETO08682.1 - 0.32 10.2 8.1 0.36 10.0 5.6 1.0 1 0 0 1 1 1 0 DHHW protein YqfQ PF14181.1 ETO08682.1 - 0.35 10.9 23.2 0.45 10.5 16.1 1.2 1 0 0 1 1 1 0 YqfQ-like protein DUF2370 PF10176.4 ETO08682.1 - 0.41 9.9 4.5 0.48 9.7 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF2201_N PF13203.1 ETO08682.1 - 0.43 9.7 10.8 0.47 9.5 7.5 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF853 PF05872.7 ETO08682.1 - 0.53 8.5 7.0 0.58 8.4 4.8 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) FLO_LFY PF01698.11 ETO08682.1 - 0.55 9.0 16.3 0.72 8.6 11.3 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Mem_trans PF03547.13 ETO08682.1 - 0.63 8.2 6.6 0.68 8.1 4.6 1.0 1 0 0 1 1 1 0 Membrane transport protein Kei1 PF08552.6 ETO08682.1 - 0.65 9.6 3.0 0.81 9.3 2.1 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 HSP90 PF00183.13 ETO08682.1 - 0.7 8.2 23.4 0.74 8.1 16.2 1.0 1 0 0 1 1 1 0 Hsp90 protein Tom37_C PF11801.3 ETO08682.1 - 0.7 9.7 12.0 0.82 9.5 8.3 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain Ycf1 PF05758.7 ETO08682.1 - 0.7 7.5 20.5 0.79 7.3 14.2 1.0 1 0 0 1 1 1 0 Ycf1 Raftlin PF15250.1 ETO08682.1 - 0.81 8.1 12.7 0.91 7.9 8.8 1.1 1 0 0 1 1 1 0 Raftlin CAF-1_p150 PF11600.3 ETO08682.1 - 0.86 8.9 44.6 1.1 8.6 30.9 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal BTV_NS2 PF04514.7 ETO08682.1 - 0.99 8.2 17.2 1.2 7.9 12.0 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF4551 PF15087.1 ETO08682.1 - 1.1 7.5 13.7 1.2 7.4 9.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) GAGA_bind PF06217.7 ETO08682.1 - 1.1 9.1 22.2 1.2 8.9 15.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Sec62 PF03839.11 ETO08682.1 - 1.3 8.3 31.4 1.7 8.0 21.7 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 LMBR1 PF04791.11 ETO08682.1 - 1.3 7.4 11.7 1.5 7.3 8.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Vfa1 PF08432.5 ETO08682.1 - 1.3 8.9 30.0 1.8 8.5 20.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 ELL PF10390.4 ETO08682.1 - 1.5 7.9 19.6 1.9 7.6 13.6 1.0 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL FHIPEP PF00771.15 ETO08682.1 - 1.7 6.8 7.1 2.1 6.5 4.9 1.1 1 0 0 1 1 1 0 FHIPEP family POX PF07526.6 ETO08682.1 - 1.7 8.8 17.9 2 8.6 12.4 1.1 1 0 0 1 1 1 0 Associated with HOX DUF2126 PF09899.4 ETO08682.1 - 1.8 6.5 6.0 2 6.3 4.2 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) RP-C_C PF11800.3 ETO08682.1 - 1.8 8.1 10.9 2.2 7.9 7.6 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Hid1 PF12722.2 ETO08682.1 - 1.9 6.0 15.7 2.2 5.8 10.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3807 PF12720.2 ETO08682.1 - 2.2 8.4 25.7 2.7 8.1 17.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) AAA_11 PF13086.1 ETO08682.1 - 2.3 7.7 13.7 2.8 7.4 9.5 1.2 1 0 0 1 1 1 0 AAA domain Paramyxo_ncap PF00973.14 ETO08682.1 - 2.4 6.7 11.8 2.6 6.6 8.2 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein SAPS PF04499.10 ETO08682.1 - 2.6 6.5 15.4 3.1 6.3 10.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Tim54 PF11711.3 ETO08682.1 - 2.9 6.3 16.4 3.8 6.0 11.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NARP1 PF12569.3 ETO08682.1 - 3 6.5 29.8 3.3 6.3 20.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 YABBY PF04690.8 ETO08682.1 - 3.4 7.8 10.9 4.1 7.6 7.5 1.1 1 0 0 1 1 1 0 YABBY protein Dynamin_N PF00350.18 ETO08682.1 - 3.8 7.2 9.1 4.8 6.9 6.3 1.2 1 0 0 1 1 1 0 Dynamin family SID-1_RNA_chan PF13965.1 ETO08682.1 - 4.1 5.4 10.6 4.5 5.3 7.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.11 ETO08682.1 - 4.1 7.2 13.8 4.8 6.9 9.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SprA-related PF12118.3 ETO08682.1 - 6.9 5.9 21.6 8.2 5.6 15.0 1.0 1 0 0 1 1 1 0 SprA-related family DDHD PF02862.12 ETO08682.1 - 7.1 6.3 19.4 8.4 6.1 13.4 1.1 1 0 0 1 1 1 0 DDHD domain Asp-B-Hydro_N PF05279.6 ETO08682.1 - 7.4 6.3 20.5 9.1 6.0 14.2 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region MRP-L46 PF11788.3 ETO08682.1 - 7.8 7.1 18.1 12 6.6 12.5 1.3 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 Hom_end_hint PF05203.11 ETO08682.1 - 7.8 6.1 11.9 9 5.9 8.2 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint Presenilin PF01080.12 ETO08682.1 - 8 5.1 8.3 8.9 5.0 5.8 1.1 1 0 0 1 1 1 0 Presenilin BSMAP PF12280.3 ETO08682.1 - 8.1 6.2 11.0 9.7 6.0 7.6 1.2 1 0 0 1 1 1 0 Brain specific membrane anchored protein Adeno_VII PF03228.9 ETO08682.1 - 8.5 7.0 11.2 12 6.5 7.8 1.3 1 0 0 1 1 1 0 Adenoviral core protein VII SOBP PF15279.1 ETO08682.1 - 9 6.5 12.5 9.1 6.5 8.7 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein Phg_2220_C PF09524.5 ETO08684.1 - 0.017 15.1 0.2 0.032 14.2 0.1 1.5 1 1 0 1 1 1 0 Conserved phage C-terminus (Phg_2220_C) DSHCT PF08148.7 ETO08684.1 - 0.089 12.0 0.0 0.094 11.9 0.0 1.2 1 0 0 1 1 1 0 DSHCT (NUC185) domain WD40 PF00400.27 ETO08685.1 - 1.1e-51 170.9 13.1 1.6e-13 49.9 0.0 6.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO08685.1 - 3.4e-09 35.4 0.2 0.00026 19.4 0.0 3.0 1 1 2 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.3 ETO08685.1 - 4.1e-08 31.8 0.4 0.0084 14.2 0.0 3.2 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 ETO08685.1 - 4.1e-06 25.8 2.3 4.6e-05 22.4 0.5 2.2 1 1 1 2 2 2 1 Coatomer WD associated region PD40 PF07676.7 ETO08685.1 - 1.5e-05 24.5 10.0 0.04 13.5 0.0 6.4 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat DUF1797 PF08796.5 ETO08685.1 - 2e-05 24.3 0.0 7.7 6.4 0.0 4.4 3 1 1 4 4 4 1 Protein of unknown function (DUF1797) Nbas_N PF15492.1 ETO08685.1 - 0.00038 19.6 1.0 2.2 7.3 0.0 3.7 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 ETO08685.1 - 0.00086 18.1 8.5 0.27 9.9 0.6 4.4 1 1 1 3 3 3 2 Nup133 N terminal like Proteasome_A_N PF10584.4 ETO08685.1 - 0.43 9.9 10.0 15 4.9 0.0 4.9 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature F5_F8_type_C PF00754.20 ETO08686.1 - 0.003 17.4 0.1 0.019 14.8 0.0 2.2 2 0 0 2 2 2 1 F5/8 type C domain NOT2_3_5 PF04153.13 ETO08687.1 - 2.6e-06 27.3 0.4 2.6e-06 27.3 0.3 2.9 3 1 0 3 3 3 1 NOT2 / NOT3 / NOT5 family TPR_11 PF13414.1 ETO08689.1 - 7.8e-12 44.6 7.6 3.6e-09 36.1 1.6 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETO08689.1 - 4.9e-10 38.5 5.3 0.0011 18.5 0.4 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO08689.1 - 5.8e-09 35.2 5.1 0.0021 17.8 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat FKBP_C PF00254.23 ETO08689.1 - 9.2e-07 28.8 0.0 2e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_9 PF13371.1 ETO08689.1 - 3.4e-06 26.8 0.2 6.5e-06 25.9 0.2 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO08689.1 - 7.6e-06 26.4 2.7 0.00014 22.4 0.4 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO08689.1 - 1.2e-05 25.5 1.8 0.00042 20.6 0.8 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO08689.1 - 0.00013 21.8 1.7 0.17 11.8 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO08689.1 - 0.0011 19.4 1.5 0.048 14.3 0.1 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO08689.1 - 0.013 15.6 0.9 0.94 9.8 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 ETO08689.1 - 0.027 14.6 5.0 0.33 11.1 0.7 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 ETO08689.1 - 0.068 12.9 0.2 0.068 12.9 0.1 3.6 3 1 2 5 5 5 0 Tetratricopeptide repeat Rapamycin_bind PF08771.6 ETO08689.1 - 0.14 12.2 1.7 2.5 8.2 0.0 2.9 2 1 1 3 3 3 0 Rapamycin binding domain PseudoU_synth_2 PF00849.17 ETO08692.1 - 2.1e-10 40.6 0.0 4.7e-10 39.5 0.0 1.6 1 1 0 1 1 1 1 RNA pseudouridylate synthase Ricin_B_lectin PF00652.17 ETO08694.1 - 0.27 11.2 6.8 0.04 13.9 1.3 2.1 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain SoxE PF06525.6 ETO08694.1 - 1.6 8.0 4.5 0.48 9.6 0.8 1.9 2 1 0 2 2 2 0 Sulfocyanin (SoxE) POPLD PF08170.7 ETO08695.1 - 4.7 7.1 6.4 3.2 7.6 0.3 2.9 1 1 1 3 3 3 0 POPLD (NUC188) domain RCC1 PF00415.13 ETO08698.1 - 3.4e-09 36.7 0.5 1.6e-08 34.6 0.0 2.4 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO08698.1 - 1.7e-07 30.6 4.5 0.015 14.9 0.6 3.8 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Exo_endo_phos_2 PF14529.1 ETO08699.1 - 8.8e-10 38.2 2.9 1.1e-09 37.9 0.9 1.9 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Kelch_6 PF13964.1 ETO08701.1 - 0.00079 19.4 0.3 0.0054 16.8 0.0 2.3 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.20 ETO08701.1 - 0.13 11.8 4.1 0.77 9.3 0.0 3.3 4 0 0 4 4 4 0 Kelch motif ICAT PF06384.6 ETO08704.1 - 0.065 13.0 0.7 0.32 10.8 0.1 2.1 2 0 0 2 2 2 0 Beta-catenin-interacting protein ICAT Rad4 PF03835.10 ETO08704.1 - 1 8.7 7.8 2.2 7.6 5.3 1.8 1 1 0 1 1 1 0 Rad4 transglutaminase-like domain G-7-MTase PF12803.2 ETO08704.1 - 1.1 8.3 8.5 0.27 10.3 0.1 2.1 2 0 0 2 2 2 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) DUF3807 PF12720.2 ETO08704.1 - 1.3 9.1 11.0 4.9 7.2 7.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) DOR PF14839.1 ETO08704.1 - 7.1 6.3 10.0 10 5.7 6.9 1.2 1 0 0 1 1 1 0 DOR family WD40 PF00400.27 ETO08706.1 - 1.7e-74 243.2 18.0 2.1e-14 52.7 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO08706.1 - 3.9e-07 28.7 0.9 0.012 13.8 0.0 3.0 3 0 0 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.3 ETO08706.1 - 6.8e-07 27.7 9.7 0.073 11.1 0.4 4.8 1 1 4 5 5 5 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO08706.1 - 0.0014 18.0 0.4 0.027 13.9 0.2 2.6 1 1 1 2 2 2 2 PQQ-like domain BBS2_Mid PF14783.1 ETO08706.1 - 0.0034 17.1 0.9 2.4 7.9 0.0 4.3 3 1 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Gmad1 PF10647.4 ETO08706.1 - 0.0096 15.3 0.0 3.3 7.0 0.0 2.3 2 0 0 2 2 2 2 Lipoprotein LpqB beta-propeller domain Resistin PF06954.6 ETO08706.1 - 0.019 15.2 0.1 5.4 7.3 0.0 3.7 2 1 1 3 3 3 0 Resistin PD40 PF07676.7 ETO08706.1 - 0.11 12.2 12.1 6.3 6.5 0.0 5.8 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Ricin_B_lectin PF00652.17 ETO08706.1 - 1.8 8.6 5.3 5.4 7.0 0.4 3.2 1 1 3 4 4 4 0 Ricin-type beta-trefoil lectin domain UPF0182 PF03699.8 ETO08707.1 - 0.56 8.0 13.7 0.62 7.9 9.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) IBV_3C PF03620.8 ETO08708.1 - 3.2 7.6 5.4 1.6 8.6 0.2 2.2 1 1 1 2 2 2 0 IBV 3C protein Gb3_synth PF04572.7 ETO08709.1 - 0.025 14.2 0.8 0.068 12.8 0.6 1.7 1 0 0 1 1 1 0 Alpha 1,4-glycosyltransferase conserved region MFS_1 PF07690.11 ETO08711.1 - 3.6e-31 108.1 15.8 4.5e-31 107.8 10.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETO08711.1 - 2e-05 23.4 9.8 2e-05 23.4 6.8 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter DUF21 PF01595.15 ETO08711.1 - 1.5 8.0 8.7 1.9 7.7 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function DUF21 DLIC PF05783.6 ETO08712.1 - 0.0025 16.5 8.5 0.065 11.8 0.1 2.3 1 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) FeoB_N PF02421.13 ETO08712.1 - 0.066 12.4 0.2 0.19 10.9 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B MMR_HSR1 PF01926.18 ETO08712.1 - 0.13 12.2 0.9 0.24 11.3 0.6 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF3810 PF12725.2 ETO08712.1 - 5.6 5.7 9.5 1.1 8.1 3.9 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3810) Dna2 PF08696.6 ETO08714.1 - 3e-11 43.0 0.1 5.8e-11 42.0 0.1 1.5 1 1 0 1 1 1 1 DNA replication factor Dna2 WD40 PF00400.27 ETO08715.1 - 2.2e-20 71.7 13.5 2.6e-10 39.7 0.8 2.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO08715.1 - 5e-08 31.5 0.9 0.00072 17.8 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PSI PF01437.20 ETO08715.1 - 0.0067 16.5 0.8 0.013 15.5 0.6 1.6 1 1 0 1 1 1 1 Plexin repeat DUF4221 PF13970.1 ETO08715.1 - 0.048 12.9 5.6 0.34 10.1 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4221) C2-set_2 PF08205.7 ETO08715.1 - 0.36 10.7 2.8 2.9 7.8 0.1 2.2 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain UPF0086 PF01868.11 ETO08716.1 - 0.038 13.6 0.2 0.057 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function UPF0086 AAA PF00004.24 ETO08717.1 - 0.014 15.6 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mlo PF03094.10 ETO08717.1 - 0.021 12.9 0.3 0.025 12.7 0.2 1.2 1 0 0 1 1 1 0 Mlo family DUF1041 PF06292.12 ETO08718.1 - 0.013 15.6 0.1 0.013 15.6 0.0 2.8 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1041) HPIH PF13323.1 ETO08718.1 - 0.12 12.0 2.4 0.59 9.8 0.1 2.3 2 0 0 2 2 2 0 N-terminal domain with HPIH motif ETRAMP PF09716.5 ETO08718.1 - 0.35 10.8 8.1 0.89 9.5 4.4 2.3 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Lectin_C PF00059.16 ETO08718.1 - 6.5 7.4 11.4 0.32 11.6 1.3 2.9 2 1 1 3 3 3 0 Lectin C-type domain Lycopene_cycl PF05834.7 ETO08719.1 - 0.072 11.9 0.0 0.098 11.5 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein ETRAMP PF09716.5 ETO08720.1 - 0.0041 17.0 5.7 0.0041 17.0 4.0 2.4 2 1 0 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) NPR3 PF03666.8 ETO08720.1 - 0.79 8.1 13.7 0.34 9.3 0.1 2.0 1 1 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 WBP-1 PF11669.3 ETO08720.1 - 1.9 8.5 5.1 7.6 6.6 1.0 2.7 1 1 1 2 2 2 0 WW domain-binding protein 1 Ribosomal_S5 PF00333.15 ETO08721.1 - 2.8e-06 26.9 0.1 4.4e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 ETO08721.1 - 0.0051 16.0 0.0 0.008 15.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain NACHT PF05729.7 ETO08722.1 - 2.2e-05 24.1 0.0 3.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Uteroglobin PF01099.12 ETO08722.1 - 0.022 14.5 0.6 0.045 13.5 0.4 1.4 1 0 0 1 1 1 0 Uteroglobin family Stk19 PF10494.4 ETO08722.1 - 0.044 13.1 1.3 0.05 12.9 0.9 1.1 1 0 0 1 1 1 0 Serine-threonine protein kinase 19 SMC_N PF02463.14 ETO08722.1 - 0.11 11.7 0.0 0.11 11.7 0.0 1.6 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain LMBR1 PF04791.11 ETO08724.1 - 0.0042 15.7 0.0 0.0042 15.7 0.0 3.5 2 1 1 4 4 4 2 LMBR1-like membrane protein NdhL PF10716.4 ETO08725.1 - 0.19 11.5 1.7 0.3 10.8 1.2 1.3 1 0 0 1 1 1 0 NADH dehydrogenase transmembrane subunit MIP-T3 PF10243.4 ETO08725.1 - 0.73 8.2 40.6 0.94 7.8 28.1 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CDC27 PF09507.5 ETO08725.1 - 1.8 7.7 32.5 2.3 7.3 22.5 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SprA-related PF12118.3 ETO08725.1 - 1.8 7.8 21.9 2.4 7.4 15.2 1.1 1 0 0 1 1 1 0 SprA-related family DUF2201_N PF13203.1 ETO08725.1 - 2.5 7.1 14.5 3.4 6.7 10.0 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF4662 PF15578.1 ETO08725.1 - 2.7 7.5 18.1 3.4 7.1 12.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) Parvo_coat PF00740.13 ETO08725.1 - 2.8 6.7 13.1 3.4 6.5 9.1 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Transformer PF06495.6 ETO08725.1 - 4.1 7.2 14.7 6.2 6.6 10.2 1.3 1 0 0 1 1 1 0 Fruit fly transformer protein DUF2413 PF10310.4 ETO08725.1 - 5.1 5.8 23.3 7.9 5.1 16.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) SOBP PF15279.1 ETO08725.1 - 5.4 7.3 9.8 6.5 7.0 6.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Apc3 PF12895.2 ETO08727.1 - 1.7e-09 37.6 11.6 0.0079 16.3 0.0 5.7 3 1 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 APC8 PF04049.8 ETO08727.1 - 7.1e-07 29.0 0.4 0.0062 16.2 0.1 2.6 1 1 1 2 2 2 2 Anaphase promoting complex subunit 8 / Cdc23 TPR_2 PF07719.12 ETO08727.1 - 3.2e-05 23.5 15.3 0.0009 18.9 0.2 5.1 6 0 0 6 6 5 2 Tetratricopeptide repeat MIT PF04212.13 ETO08727.1 - 0.00033 20.4 0.6 0.0036 17.1 0.0 2.5 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_12 PF13424.1 ETO08727.1 - 0.0012 18.7 10.7 0.13 12.2 0.1 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO08727.1 - 0.003 18.0 4.0 0.028 15.0 0.2 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO08727.1 - 0.0031 17.0 0.2 0.0031 17.0 0.1 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO08727.1 - 0.0068 16.7 1.6 0.18 12.1 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO08727.1 - 0.01 16.4 1.0 0.77 10.5 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 ETO08727.1 - 0.013 15.6 4.1 0.21 11.8 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETO08727.1 - 0.023 14.4 3.2 0.41 10.5 0.1 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.7 ETO08727.1 - 0.026 15.1 7.5 3 8.6 0.1 4.6 3 1 1 4 4 4 0 Sel1 repeat TPR_15 PF13429.1 ETO08727.1 - 0.049 12.6 0.0 0.67 8.9 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO08727.1 - 0.19 12.2 1.0 84 3.9 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat VirB3 PF05101.8 ETO08727.1 - 0.19 11.6 0.8 0.32 10.9 0.1 1.7 2 0 0 2 2 1 0 Type IV secretory pathway, VirB3-like protein TPR_7 PF13176.1 ETO08727.1 - 1.5 8.7 8.0 0.53 10.2 0.1 3.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 ETO08727.1 - 2.1 8.3 6.2 13 5.8 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 ETO08727.1 - 4 7.1 11.0 1.4 8.6 0.1 4.0 5 0 0 5 5 5 0 TPR repeat DUF230 PF03003.11 ETO08728.1 - 0.2 11.1 2.6 0.12 11.9 0.7 1.4 1 1 1 2 2 2 0 Poxvirus proteins of unknown function Apis_Csd PF11671.3 ETO08728.1 - 3.6 7.3 8.3 3.8 7.3 5.7 1.0 1 0 0 1 1 1 0 Complementary sex determiner protein DUF2514 PF10721.4 ETO08728.1 - 5.9 6.5 7.3 6.4 6.4 5.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) CIAPIN1 PF05093.8 ETO08728.1 - 6.7 6.8 12.1 7.6 6.6 8.4 1.1 1 0 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Rtf2 PF04641.7 ETO08728.1 - 9.5 5.3 20.2 11 5.1 14.0 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Kelch_6 PF13964.1 ETO08729.1 - 0.009 16.1 0.9 0.11 12.7 0.0 2.7 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.20 ETO08729.1 - 0.018 14.5 0.5 0.2 11.2 0.1 2.4 2 0 0 2 2 2 0 Kelch motif Spt5_N PF11942.3 ETO08730.1 - 0.028 15.0 28.4 0.098 13.2 10.8 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal BAAT_C PF08840.6 ETO08730.1 - 5.9 6.5 7.4 0.14 11.8 0.5 1.7 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Tom37_C PF11801.3 ETO08730.1 - 6 6.7 19.6 1 9.1 4.8 2.3 2 0 0 2 2 2 0 Tom37 C-terminal domain SdpI PF13630.1 ETO08731.1 - 0.079 12.6 0.4 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 SdpI/YhfL protein family Daxx PF03344.10 ETO08731.1 - 3.9 5.8 14.9 5.6 5.3 10.3 1.1 1 0 0 1 1 1 0 Daxx Family EF-hand_1 PF00036.27 ETO08733.1 - 0.00033 19.7 0.2 0.00084 18.4 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 ETO08733.1 - 0.0025 17.9 0.1 0.005 16.9 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO08733.1 - 0.0029 17.3 0.1 0.0064 16.2 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain SR-25 PF10500.4 ETO08733.1 - 0.013 15.0 7.2 0.026 14.0 5.0 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein EF-hand_10 PF14788.1 ETO08733.1 - 0.015 14.9 0.0 0.048 13.3 0.0 1.9 1 0 0 1 1 1 0 EF hand DUF3571 PF12095.3 ETO08734.1 - 0.17 12.1 2.7 0.14 12.4 1.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3571) Fzo_mitofusin PF04799.8 ETO08734.1 - 1.9 7.8 5.6 1.2 8.4 2.7 1.5 1 1 0 1 1 1 0 fzo-like conserved region Cortex-I_coil PF09304.5 ETO08734.1 - 2.4 8.2 10.3 1.9 8.5 5.9 1.7 1 1 1 2 2 2 0 Cortexillin I, coiled coil MutS_IV PF05190.13 ETO08736.1 - 0.0012 18.9 1.0 0.0022 18.1 0.2 2.0 2 0 0 2 2 2 1 MutS family domain IV Transposase_mut PF00872.13 ETO08736.1 - 0.066 11.7 0.5 0.13 10.7 0.0 1.7 2 0 0 2 2 2 0 Transposase, Mutator family Tctex-1 PF03645.8 ETO08736.1 - 0.071 12.9 3.7 0.95 9.3 1.4 2.5 2 1 0 2 2 2 0 Tctex-1 family WD40 PF00400.27 ETO08737.1 - 3e-26 90.3 6.2 9.1e-10 38.0 0.0 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO08737.1 - 0.00039 18.7 0.1 0.58 8.2 0.0 3.0 1 1 0 2 2 2 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO08737.1 - 0.024 14.3 0.3 1.1 9.0 0.1 3.5 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.27 ETO08742.1 - 7.9e-49 161.8 34.3 5.6e-10 38.7 0.6 8.2 7 1 1 8 8 8 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO08742.1 - 1.7e-09 36.4 6.2 0.018 13.1 0.2 5.4 1 1 3 5 5 5 4 Nucleoporin Nup120/160 DUF4349 PF14257.1 ETO08742.1 - 2.6 7.2 4.5 4.3 6.4 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF4599 PF15371.1 ETO08744.1 - 1.1 9.3 4.9 0.74 9.9 1.8 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4599) Reo_sigmaC PF04582.7 ETO08745.1 - 1.5 7.9 14.5 0.23 10.6 1.4 2.8 1 1 2 3 3 3 0 Reovirus sigma C capsid protein CCDC155 PF14662.1 ETO08745.1 - 1.7 8.1 75.2 36 3.8 20.0 3.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 zf-LITAF-like PF10601.4 ETO08746.1 - 0.043 13.6 0.3 0.068 13.0 0.2 1.4 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain DivIC PF04977.10 ETO08746.1 - 4.3 6.9 5.8 9.6 5.7 0.4 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF4613 PF15390.1 ETO08747.1 - 0.62 8.1 9.5 0.8 7.7 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) PLRV_ORF5 PF01690.12 ETO08747.1 - 2.6 7.0 13.6 3.5 6.6 9.4 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein LRRC37AB_C PF14914.1 ETO08747.1 - 3.6 7.0 9.3 0.33 10.3 2.0 2.3 2 1 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain WD40 PF00400.27 ETO08749.1 - 1e-43 145.6 2.9 4.1e-10 39.1 0.1 6.1 5 1 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO08749.1 - 1.4e-06 26.7 2.1 0.077 11.1 0.1 3.6 1 1 2 3 3 3 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO08749.1 - 0.00061 19.5 6.8 1.8 8.3 0.1 3.9 2 2 1 3 3 3 3 Ciliary BBSome complex subunit 2, middle region Cytochrom_D1 PF02239.11 ETO08749.1 - 0.0032 15.8 0.2 1 7.5 0.0 2.8 1 1 2 3 3 3 3 Cytochrome D1 heme domain PQQ PF01011.16 ETO08749.1 - 0.0044 16.4 0.0 1 9.0 0.0 4.0 5 0 0 5 5 5 1 PQQ enzyme repeat PD40 PF07676.7 ETO08749.1 - 0.057 13.1 3.3 20 4.9 0.0 3.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Kelch_6 PF13964.1 ETO08750.1 - 1.6e-08 34.3 5.5 0.12 12.6 0.3 4.8 4 1 1 5 5 5 4 Kelch motif Kelch_1 PF01344.20 ETO08750.1 - 1.3e-07 31.0 5.2 5e-05 22.7 0.2 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO08750.1 - 0.00088 18.9 2.2 0.39 10.5 0.2 4.0 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO08750.1 - 0.0018 18.0 1.5 0.54 10.0 0.1 3.6 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO08750.1 - 0.003 17.4 3.0 1.7 8.6 0.5 4.6 5 0 0 5 5 5 1 Kelch motif DUF2098 PF09871.4 ETO08751.1 - 0.015 15.2 1.4 0.032 14.1 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) DUF1314 PF07013.6 ETO08751.1 - 0.015 14.6 0.0 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1314) zf-FPG_IleRS PF06827.9 ETO08752.1 - 2.9 7.6 16.3 2.9 7.6 0.2 4.4 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS zf-LITAF-like PF10601.4 ETO08752.1 - 4.2 7.3 10.1 0.34 10.8 2.7 2.3 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Lar_restr_allev PF14354.1 ETO08752.1 - 5.8 7.2 14.9 9.4 6.6 0.1 3.5 2 2 1 3 3 3 0 Restriction alleviation protein Lar PKD_channel PF08016.7 ETO08753.1 - 1.1e-12 47.1 9.7 1.1e-12 47.1 6.7 1.9 2 1 0 2 2 2 1 Polycystin cation channel EF-hand_1 PF00036.27 ETO08753.1 - 2.6e-09 35.7 1.6 7.1e-05 21.8 0.2 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 ETO08753.1 - 8.4e-07 28.3 1.8 0.023 14.5 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 ETO08753.1 - 1.1e-06 27.7 1.6 0.026 13.8 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 ETO08753.1 - 2.1e-06 27.7 0.8 0.0036 17.4 0.0 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 ETO08753.1 - 0.0001 21.8 1.1 0.0002 20.8 0.3 2.0 1 1 1 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.4 ETO08753.1 - 0.0039 17.2 4.7 0.0078 16.2 0.1 2.5 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF2431 PF10354.4 ETO08753.1 - 0.011 15.7 2.5 0.18 11.7 0.7 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF2431) DUF1007 PF06226.8 ETO08753.1 - 0.28 10.9 4.0 2 8.1 0.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1007) WD40 PF00400.27 ETO08754.1 - 1.1e-16 59.9 11.7 8.1e-10 38.2 0.2 4.4 4 1 0 4 4 4 4 WD domain, G-beta repeat zf-CCHC PF00098.18 ETO08755.1 - 0.031 14.1 13.7 0.52 10.3 3.0 2.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 ETO08755.1 - 0.46 10.2 10.2 1 9.0 0.7 2.9 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.22 ETO08756.1 - 7e-38 130.1 0.2 1.8e-37 128.7 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 ETO08756.1 - 9.5e-21 73.6 0.2 2.8e-20 72.0 0.2 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 ETO08756.1 - 4.3e-16 59.4 0.0 1.3e-15 57.9 0.0 1.8 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 ETO08756.1 - 0.00029 21.1 0.2 0.00029 21.1 0.2 3.1 2 1 1 3 3 3 1 zinc-binding in reverse transcriptase NACHT PF05729.7 ETO08757.1 - 2.4e-09 37.0 0.1 1.3e-08 34.6 0.1 1.9 1 1 0 1 1 1 1 NACHT domain G-alpha PF00503.15 ETO08757.1 - 0.0013 17.4 2.1 0.0016 17.1 1.4 1.1 1 0 0 1 1 1 1 G-protein alpha subunit AAA_16 PF13191.1 ETO08757.1 - 0.0017 18.3 0.0 0.0023 17.9 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain DAP3 PF10236.4 ETO08757.1 - 0.0059 15.5 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 NB-ARC PF00931.17 ETO08757.1 - 0.0077 15.1 0.0 0.011 14.6 0.0 1.3 1 1 0 1 1 1 1 NB-ARC domain SMC_N PF02463.14 ETO08757.1 - 0.0089 15.2 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF2075 PF09848.4 ETO08757.1 - 0.016 14.2 0.0 0.016 14.2 0.0 2.0 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 ETO08757.1 - 0.018 15.1 0.0 0.026 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 ETO08757.1 - 0.025 14.3 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 Part of AAA domain Torsin PF06309.6 ETO08757.1 - 0.06 13.2 0.0 0.098 12.5 0.0 1.3 1 0 0 1 1 1 0 Torsin CoaE PF01121.15 ETO08757.1 - 0.078 12.3 0.0 9.2 5.6 0.0 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_18 PF13238.1 ETO08757.1 - 0.086 13.1 2.8 0.11 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Colicin-DNase PF12639.2 ETO08758.1 - 0.55 10.5 6.0 0.35 11.1 0.5 2.9 1 1 2 3 3 3 0 DNase/tRNase domain of colicin-like bacteriocin Kelch_1 PF01344.20 ETO08759.1 - 3.3e-12 45.7 2.9 1.3e-05 24.5 0.2 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO08759.1 - 3.7e-06 26.4 2.6 0.013 15.2 0.2 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO08759.1 - 3.1e-05 23.6 1.3 0.086 12.6 0.1 3.5 2 2 1 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO08759.1 - 0.00037 20.3 2.4 1 9.3 0.0 3.7 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 ETO08759.1 - 0.0004 20.4 6.9 0.019 15.1 0.4 4.1 3 1 1 4 4 4 1 Kelch motif Kelch_3 PF13415.1 ETO08759.1 - 0.00067 19.7 0.3 1.3 9.2 0.0 4.0 4 0 0 4 4 4 1 Galactose oxidase, central domain DNA_pol3_delta PF06144.8 ETO08759.1 - 0.035 13.6 0.1 0.066 12.7 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit DAP3 PF10236.4 ETO08759.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 O-antigen_lig PF13425.1 ETO08760.1 - 0.0037 17.2 4.2 0.023 14.6 0.2 2.7 3 0 0 3 3 3 1 O-antigen ligase like membrane protein Trypan_PARP PF05887.6 ETO08760.1 - 3.4 7.4 7.0 6 6.6 4.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) zf-C3HC4_3 PF13920.1 ETO08762.1 - 3.9e-11 42.4 10.0 6.4e-11 41.7 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO08762.1 - 2.3e-05 24.3 14.4 5.8e-05 23.0 10.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 ETO08762.1 - 0.0018 17.7 8.6 0.0037 16.7 6.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 MBT PF02820.13 ETO08762.1 - 0.004 17.0 0.1 0.018 14.9 0.0 2.0 2 0 0 2 2 2 1 mbt repeat SAM_1 PF00536.25 ETO08762.1 - 0.018 15.1 0.2 0.099 12.8 0.0 2.3 1 1 1 2 2 2 0 SAM domain (Sterile alpha motif) zf-RING_5 PF14634.1 ETO08762.1 - 0.023 14.4 12.0 0.056 13.1 8.3 1.7 1 0 0 1 1 1 0 zinc-RING finger domain PHF5 PF03660.9 ETO08762.1 - 0.11 12.5 4.4 0.24 11.4 3.1 1.5 1 0 0 1 1 1 0 PHF5-like protein Dala_Dala_lig_N PF01820.16 ETO08762.1 - 0.13 12.5 2.9 0.19 12.0 1.0 1.9 1 1 1 2 2 2 0 D-ala D-ala ligase N-terminus zf-C3HC4_3 PF13920.1 ETO08763.1 - 3.3e-09 36.2 15.7 5.8e-09 35.4 10.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO08763.1 - 0.00019 21.3 19.0 0.00037 20.4 13.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SAM_1 PF00536.25 ETO08763.1 - 0.00043 20.4 1.0 0.0017 18.5 0.2 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) MBT PF02820.13 ETO08763.1 - 0.00077 19.3 0.2 0.21 11.5 0.0 3.2 3 0 0 3 3 3 1 mbt repeat SH3_2 PF07653.12 ETO08763.1 - 0.014 14.8 0.1 0.059 12.8 0.0 2.1 2 0 0 2 2 2 0 Variant SH3 domain zf-RING_5 PF14634.1 ETO08763.1 - 0.11 12.2 16.1 0.19 11.4 11.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain ATP_bind_1 PF03029.12 ETO08764.1 - 6.3e-24 84.8 0.3 1.1e-23 83.9 0.2 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ATP_bind_1 PF03029.12 ETO08765.1 - 5.8e-42 143.8 0.0 7.2e-42 143.5 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 ETO08765.1 - 6.3e-06 26.3 0.0 8.3e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETO08765.1 - 2.7e-05 24.2 0.0 2.8e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 ETO08765.1 - 3.5e-05 23.7 0.0 5.2e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 ETO08765.1 - 7.6e-05 22.4 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 ETO08765.1 - 0.00014 22.6 0.0 0.0002 22.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 ETO08765.1 - 0.00021 20.8 0.0 0.0067 15.8 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Arf PF00025.16 ETO08765.1 - 0.00023 20.4 0.0 0.00031 20.0 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_18 PF13238.1 ETO08765.1 - 0.00028 21.1 0.0 0.00041 20.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 ETO08765.1 - 0.00036 20.4 0.1 0.00071 19.5 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.1 ETO08765.1 - 0.00038 20.0 0.0 0.00053 19.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 ETO08765.1 - 0.00076 18.9 0.0 0.061 12.7 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.18 ETO08765.1 - 0.0012 18.3 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain PduV-EutP PF10662.4 ETO08765.1 - 0.0012 18.3 0.2 0.021 14.2 0.0 2.6 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 ETO08765.1 - 0.0013 18.2 0.1 0.0067 15.8 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain NB-ARC PF00931.17 ETO08765.1 - 0.0016 17.3 0.0 0.0024 16.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain MobB PF03205.9 ETO08765.1 - 0.0019 17.9 0.0 0.003 17.2 0.0 1.4 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 ETO08765.1 - 0.0021 17.8 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase G-alpha PF00503.15 ETO08765.1 - 0.0021 16.8 0.1 0.0036 16.0 0.0 1.4 1 1 0 1 1 1 1 G-protein alpha subunit AAA_30 PF13604.1 ETO08765.1 - 0.0029 17.2 0.0 0.0038 16.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 ETO08765.1 - 0.0035 16.8 0.0 0.0044 16.5 0.0 1.1 1 0 0 1 1 1 1 AAA-like domain Zeta_toxin PF06414.7 ETO08765.1 - 0.0051 15.9 0.0 0.0075 15.3 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_14 PF13173.1 ETO08765.1 - 0.0064 16.3 0.2 0.019 14.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 ETO08765.1 - 0.013 14.4 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein MipZ PF09140.6 ETO08765.1 - 0.014 14.5 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 ATPase MipZ SRPRB PF09439.5 ETO08765.1 - 0.017 14.3 0.0 0.05 12.8 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PhoH PF02562.11 ETO08765.1 - 0.018 14.2 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein NTPase_1 PF03266.10 ETO08765.1 - 0.018 14.7 0.0 0.5 10.0 0.0 2.1 2 0 0 2 2 2 0 NTPase Viral_helicase1 PF01443.13 ETO08765.1 - 0.019 14.5 0.0 0.022 14.2 0.0 1.3 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Adeno_IVa2 PF02456.10 ETO08765.1 - 0.02 13.5 0.1 0.024 13.3 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein Miro PF08477.8 ETO08765.1 - 0.024 15.1 0.0 0.07 13.6 0.0 1.7 1 1 1 2 2 1 0 Miro-like protein DUF2075 PF09848.4 ETO08765.1 - 0.025 13.5 0.0 0.026 13.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 ETO08765.1 - 0.027 13.8 0.1 0.13 11.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.15 ETO08765.1 - 0.038 13.6 0.0 0.044 13.4 0.0 1.3 1 1 0 1 1 1 0 Adenylylsulphate kinase AAA_29 PF13555.1 ETO08765.1 - 0.038 13.5 0.1 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 ETO08765.1 - 0.041 13.6 0.0 0.063 13.0 0.0 1.2 1 0 0 1 1 1 0 Part of AAA domain PRK PF00485.13 ETO08765.1 - 0.048 13.2 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family FtsK_SpoIIIE PF01580.13 ETO08765.1 - 0.051 13.0 0.0 0.063 12.7 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family ATP-synt_ab PF00006.20 ETO08765.1 - 0.052 13.0 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.9 ETO08765.1 - 0.055 13.1 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Armet PF10208.4 ETO08765.1 - 0.059 13.0 0.0 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding DUF258 PF03193.11 ETO08765.1 - 0.062 12.4 0.1 0.12 11.5 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF258 UPF0079 PF02367.12 ETO08765.1 - 0.064 12.8 0.0 0.083 12.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF87 PF01935.12 ETO08765.1 - 0.084 12.6 0.1 0.12 12.2 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function DUF87 ABC_tran PF00005.22 ETO08765.1 - 0.11 12.8 0.2 0.15 12.3 0.1 1.4 1 1 0 1 1 1 0 ABC transporter ArgK PF03308.11 ETO08765.1 - 0.11 11.2 0.0 0.24 10.1 0.0 1.5 2 0 0 2 2 2 0 ArgK protein AAA_28 PF13521.1 ETO08765.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.5 2 0 0 2 2 1 0 AAA domain TRM PF02005.11 ETO08766.1 - 3.8e-66 223.5 0.1 4.8e-66 223.2 0.1 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 ETO08766.1 - 0.014 15.0 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Spermine_synth PF01564.12 ETO08766.1 - 0.032 13.1 0.0 0.07 12.0 0.0 1.5 1 0 0 1 1 1 0 Spermine/spermidine synthase WD40 PF00400.27 ETO08768.1 - 8.3e-06 25.4 0.9 0.16 11.8 0.5 3.6 3 1 1 4 4 4 2 WD domain, G-beta repeat RVP PF00077.15 ETO08769.1 - 0.00011 22.0 0.1 0.00019 21.2 0.1 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease HTH_44 PF14641.1 ETO08769.1 - 0.011 15.7 0.0 0.027 14.4 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix DNA-binding domain of SPT6 DUF1436 PF07262.6 ETO08769.1 - 0.011 15.2 0.3 0.18 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1436) SFTA2 PF15210.1 ETO08769.1 - 0.053 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Surfactant-associated protein 2 Asp_protease_2 PF13650.1 ETO08769.1 - 0.11 12.9 0.1 0.27 11.7 0.0 1.7 1 1 0 1 1 1 0 Aspartyl protease Peptidase_C71 PF12386.3 ETO08769.1 - 0.12 11.7 0.1 0.3 10.4 0.0 1.7 2 0 0 2 2 2 0 Pseudomurein endo-isopeptidase Pei DUF2487 PF10673.4 ETO08770.1 - 0.015 15.1 4.5 1.1 9.0 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2487) Thioredoxin_8 PF13905.1 ETO08770.1 - 0.16 12.1 5.3 0.24 11.5 2.6 2.0 1 1 1 2 2 2 0 Thioredoxin-like HTH_19 PF12844.2 ETO08770.1 - 0.5 10.4 4.6 1.3 9.1 0.9 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain 3Beta_HSD PF01073.14 ETO08772.1 - 1.7e-14 53.2 0.0 1.9e-14 53.0 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 ETO08772.1 - 4e-13 49.3 0.0 4.7e-13 49.1 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETO08772.1 - 1e-11 45.1 0.0 1.6e-11 44.5 0.0 1.3 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 ETO08772.1 - 3.8e-07 29.6 0.0 4.6e-07 29.3 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 ETO08772.1 - 1.7e-05 24.7 0.0 2.5e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 ETO08772.1 - 0.00048 19.1 0.1 0.0029 16.5 0.1 1.9 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 ETO08772.1 - 0.0087 14.9 0.0 0.0097 14.8 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 ETO08772.1 - 0.025 14.2 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 KR domain DUF4135 PF13575.1 ETO08772.1 - 0.028 13.4 0.0 0.031 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Sina PF03145.11 ETO08772.1 - 0.079 12.6 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Seven in absentia protein family Raftlin PF15250.1 ETO08773.1 - 0.5 8.8 11.6 0.71 8.3 8.0 1.2 1 0 0 1 1 1 0 Raftlin Pkinase PF00069.20 ETO08774.1 - 2.3e-29 102.3 0.6 2.3e-29 102.3 0.4 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO08774.1 - 1.3e-15 57.2 1.3 4.2e-15 55.5 0.2 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase PX PF00787.19 ETO08774.1 - 1.8e-12 47.0 5.7 6.3e-11 42.0 4.0 2.9 1 1 0 1 1 1 1 PX domain ABC2_membrane_3 PF12698.2 ETO08774.1 - 0.044 12.8 1.4 0.068 12.2 0.9 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Pkinase PF00069.20 ETO08775.1 - 1.4e-36 125.9 0.0 2.7e-36 125.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO08775.1 - 8.4e-18 64.3 0.0 1.2e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 ETO08775.1 - 0.00048 20.6 0.8 0.00048 20.6 0.6 2.4 2 0 0 2 2 2 1 Protein kinase C terminal domain MENTAL PF10457.4 ETO08777.1 - 0.011 15.3 1.2 0.016 14.7 0.0 1.8 2 0 0 2 2 2 0 Cholesterol-capturing domain Glyco_hydro_20 PF00728.17 ETO08778.1 - 1.4e-24 86.9 8.1 2.2e-24 86.3 5.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Metallophos PF00149.23 ETO08778.1 - 0.011 15.1 1.1 0.014 14.8 0.7 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Glyco_hydro_20 PF00728.17 ETO08779.1 - 1.1e-48 166.1 0.0 1.6e-48 165.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 ETO08779.1 - 4.9e-18 66.0 0.0 9.3e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 ETO08779.1 - 0.00046 20.7 0.0 0.0007 20.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 RVT_1 PF00078.22 ETO08780.1 - 8e-21 74.3 0.1 2.2e-20 72.9 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 ETO08780.1 - 0.0053 17.1 0.0 0.02 15.2 0.0 1.9 2 0 0 2 2 2 1 RNase H Peptidase_C14 PF00656.17 ETO08781.1 - 0.00025 20.8 1.9 0.00031 20.5 0.4 1.7 1 1 0 2 2 2 1 Caspase domain SWIB PF02201.13 ETO08781.1 - 0.064 12.9 0.1 11 5.8 0.0 2.9 2 0 0 2 2 2 0 SWIB/MDM2 domain DnaJ PF00226.26 ETO08782.1 - 0.0089 15.7 0.9 0.017 14.8 0.0 1.9 2 0 0 2 2 2 1 DnaJ domain Pax7 PF12360.3 ETO08782.1 - 0.018 15.2 0.1 0.018 15.2 0.1 2.5 2 0 0 2 2 2 0 Paired box protein 7 Kelch_3 PF13415.1 ETO08783.1 - 1.3e-08 34.7 0.1 0.0029 17.7 0.0 4.4 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO08783.1 - 1.1e-07 31.7 12.2 0.0025 17.9 0.1 5.2 6 1 1 7 7 7 2 Kelch motif Kelch_2 PF07646.10 ETO08783.1 - 0.0001 21.9 1.4 0.77 9.6 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 ETO08783.1 - 0.00013 21.7 4.3 0.053 13.4 0.4 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO08783.1 - 0.00016 21.1 3.6 0.074 12.6 0.1 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETO08783.1 - 0.0037 16.9 0.7 1.3 8.8 0.0 3.9 4 0 0 4 4 4 1 Galactose oxidase, central domain Cupin_8 PF13621.1 ETO08784.1 - 5.6e-46 157.0 10.7 4.2e-45 154.2 7.4 2.7 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 ETO08784.1 - 0.0025 17.0 0.1 0.0094 15.2 0.0 2.0 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.17 ETO08784.1 - 0.0077 16.4 1.0 0.069 13.4 0.0 2.8 3 0 0 3 3 3 1 JmjC domain, hydroxylase 2OG-FeII_Oxy_5 PF13759.1 ETO08784.1 - 0.1 12.8 5.3 0.97 9.7 0.0 2.9 3 0 0 3 3 3 0 Putative 2OG-Fe(II) oxygenase YchF-GTPase_C PF06071.8 ETO08785.1 - 2.7e-38 129.6 0.8 6.4e-38 128.4 0.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 ETO08785.1 - 2.2e-17 63.0 0.0 5.2e-17 61.8 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETO08785.1 - 2.2e-05 23.7 0.0 4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 ETO08785.1 - 0.015 15.7 0.0 0.1 13.0 0.0 2.4 2 1 0 2 2 2 0 Miro-like protein Ras PF00071.17 ETO08785.1 - 0.047 13.0 0.0 0.13 11.6 0.0 1.8 1 1 0 1 1 1 0 Ras family NicO PF03824.11 ETO08785.1 - 0.081 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein WD40 PF00400.27 ETO08786.1 - 1e-64 212.2 15.3 1.9e-12 46.5 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO08786.1 - 8.9e-08 30.7 8.9 0.047 11.8 1.2 5.5 1 1 4 5 5 5 5 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO08786.1 - 4.9e-06 26.1 1.8 0.00024 20.6 0.2 2.6 1 1 1 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 ETO08786.1 - 0.00033 19.5 8.0 1.1 7.9 0.1 3.8 1 1 1 2 2 2 2 Nup133 N terminal like DUF1652 PF07865.6 ETO08786.1 - 0.0022 17.5 0.0 18 4.9 0.0 4.0 3 1 1 4 4 4 1 Protein of unknown function (DUF1652) Cytochrom_D1 PF02239.11 ETO08786.1 - 0.012 13.9 0.4 0.26 9.5 0.1 2.2 1 1 1 2 2 2 0 Cytochrome D1 heme domain DUF4468 PF14730.1 ETO08787.1 - 0.048 13.3 2.7 0.053 13.2 0.2 2.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4468) with TBP-like fold TRAP-gamma PF07074.7 ETO08787.1 - 3.1 7.2 8.3 0.38 10.2 1.2 2.1 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) WD40 PF00400.27 ETO08788.1 - 1.4e-14 53.2 3.3 1.3e-11 43.8 0.1 2.6 3 0 0 3 3 3 2 WD domain, G-beta repeat DivIC PF04977.10 ETO08789.1 - 0.02 14.3 2.0 0.02 14.3 1.4 3.7 3 1 1 4 4 4 0 Septum formation initiator DUF883 PF05957.8 ETO08789.1 - 0.43 10.9 1.6 0.69 10.3 0.3 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF2075 PF09848.4 ETO08789.1 - 5.2 5.9 15.3 9.7 5.0 10.6 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) H_PPase PF03030.11 ETO08790.1 - 0.14 10.4 0.6 2.3 6.3 0.1 2.0 2 0 0 2 2 2 0 Inorganic H+ pyrophosphatase NB-ARC PF00931.17 ETO08791.1 - 0.26 10.1 2.6 0.12 11.1 0.3 1.5 2 0 0 2 2 2 0 NB-ARC domain WD40 PF00400.27 ETO08792.1 - 0.00011 21.9 0.2 0.002 17.9 0.0 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat NACHT PF05729.7 ETO08793.1 - 8.3e-10 38.5 0.0 1.6e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETO08793.1 - 2.6e-05 24.3 0.0 0.00011 22.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETO08793.1 - 0.00025 21.3 0.0 0.00025 21.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain KaiC PF06745.8 ETO08793.1 - 0.0026 16.9 3.2 0.013 14.6 0.0 3.1 3 1 1 4 4 4 1 KaiC AAA_17 PF13207.1 ETO08793.1 - 0.0037 18.0 0.6 0.033 14.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA PF00004.24 ETO08793.1 - 0.0094 16.1 0.1 0.029 14.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 ETO08793.1 - 0.051 13.7 3.6 0.084 13.0 0.2 3.0 1 1 1 2 2 2 0 RNA helicase AAA_16 PF13191.1 ETO08793.1 - 0.055 13.4 0.3 1.1 9.2 0.0 2.3 1 1 1 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 ETO08793.1 - 0.11 12.3 0.0 0.32 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 ETO08793.1 - 0.2 11.9 1.2 0.71 10.1 0.0 2.5 3 0 0 3 3 3 0 ABC transporter WD40 PF00400.27 ETO08794.1 - 3.7e-65 213.6 21.7 2e-10 40.0 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO08794.1 - 3.3e-07 28.8 3.7 0.026 12.6 0.1 5.4 1 1 5 6 6 6 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO08794.1 - 0.00034 19.0 0.1 0.016 13.4 0.0 2.6 2 1 0 2 2 2 1 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO08794.1 - 0.039 13.3 0.0 0.13 11.6 0.0 1.7 2 1 0 2 2 2 0 PQQ-like domain Ricin_B_lectin PF00652.17 ETO08794.1 - 0.17 11.9 1.7 0.58 10.1 0.1 2.4 2 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain zf-C3HC4_2 PF13923.1 ETO08795.1 - 0.062 13.3 5.8 0.23 11.5 0.1 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO08795.1 - 4.3 7.2 5.9 4.7 7.1 2.1 2.4 1 1 1 2 2 2 0 Ring finger domain PPV_E1_N PF00524.13 ETO08798.1 - 0.066 13.4 0.2 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 E1 Protein, N terminal domain Innate_immun PF12782.2 ETO08799.1 - 0.023 13.9 0.9 0.022 14.0 0.6 1.1 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Folate_carrier PF01770.13 ETO08799.1 - 0.033 12.6 1.1 0.041 12.4 0.7 1.1 1 0 0 1 1 1 0 Reduced folate carrier Rhabdo_ncap PF00945.13 ETO08799.1 - 0.05 12.1 1.1 0.057 11.9 0.7 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein RXT2_N PF08595.6 ETO08799.1 - 0.057 13.2 3.3 0.074 12.8 2.3 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Mss4 PF04421.8 ETO08799.1 - 0.09 12.6 3.2 0.11 12.3 1.0 1.8 1 1 1 2 2 2 0 Mss4 protein DUF3484 PF11983.3 ETO08799.1 - 1.1 10.1 4.3 0.51 11.2 1.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3484) Pkinase PF00069.20 ETO08801.1 - 2.1e-10 40.1 0.0 3e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pox_ser-thr_kin PF05445.6 ETO08801.1 - 0.04 12.7 0.2 0.056 12.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase G_glu_transpept PF01019.16 ETO08802.1 - 3e-74 250.3 0.0 1.1e-38 132.9 0.0 3.1 1 1 2 3 3 3 3 Gamma-glutamyltranspeptidase CAP_GLY PF01302.20 ETO08803.1 - 0.018 14.7 0.1 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 CAP-Gly domain NOC3p PF07540.6 ETO08804.1 - 0.035 14.3 0.6 0.11 12.7 0.0 2.0 1 1 1 2 2 2 0 Nucleolar complex-associated protein DegS PF05384.6 ETO08805.1 - 0.02 14.0 1.1 0.024 13.8 0.7 1.2 1 0 0 1 1 1 0 Sensor protein DegS GLTP PF08718.6 ETO08805.1 - 0.026 14.5 1.1 0.034 14.1 0.7 1.2 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) DUF1640 PF07798.6 ETO08805.1 - 0.049 13.6 4.6 0.051 13.6 3.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) mRNA_cap_C PF03919.10 ETO08805.1 - 0.059 13.6 1.4 0.11 12.8 0.9 1.5 1 1 0 1 1 1 0 mRNA capping enzyme, C-terminal domain Laminin_II PF06009.7 ETO08805.1 - 0.088 12.5 2.0 0.094 12.4 1.4 1.0 1 0 0 1 1 1 0 Laminin Domain II DUF342 PF03961.8 ETO08805.1 - 0.21 9.9 2.9 0.23 9.8 2.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Nucleic_acid_bd PF13820.1 ETO08805.1 - 0.22 11.1 1.9 2.3 7.8 0.2 2.0 1 1 1 2 2 2 0 Putative nucleic acid-binding region DUF573 PF04504.9 ETO08805.1 - 0.49 10.6 7.5 0.14 12.4 2.4 1.8 1 1 1 2 2 2 0 Protein of unknown function, DUF573 DUF3449 PF11931.3 ETO08807.1 - 0.47 9.9 4.5 0.25 10.8 1.5 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3449) Acyl-CoA_dh_N PF02771.11 ETO08809.1 - 1.7e-08 34.9 0.3 2.4e-08 34.5 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Dabb PF07876.7 ETO08809.1 - 0.051 14.0 0.0 0.12 12.8 0.0 1.6 1 1 0 1 1 1 0 Stress responsive A/B Barrel Domain DUF221 PF02714.10 ETO08810.1 - 2.5e-48 164.6 27.4 2.1e-47 161.5 19.0 1.9 1 1 0 1 1 1 1 Domain of unknown function DUF221 PDR_CDR PF06422.7 ETO08810.1 - 6.7 6.4 6.9 0.28 10.8 0.2 2.1 2 0 0 2 2 2 0 CDR ABC transporter CLP_protease PF00574.18 ETO08811.1 - 2e-06 27.6 0.0 2.8e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Clp protease Aminotran_5 PF00266.14 ETO08812.1 - 2.3e-11 43.0 0.0 3.9e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Phage_TAC PF06222.6 ETO08812.1 - 0.077 12.5 0.7 0.14 11.6 0.5 1.5 1 0 0 1 1 1 0 Phage tail assembly chaperone Dynamin_N PF00350.18 ETO08813.1 - 8.7e-09 35.4 0.0 9.6e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 ETO08813.1 - 0.00062 19.7 0.0 0.0007 19.5 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 ETO08813.1 - 0.0074 15.7 0.1 0.031 13.7 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 ETO08813.1 - 0.071 12.2 0.0 0.085 11.9 0.0 1.1 1 0 0 1 1 1 0 AIG1 family EF-hand_4 PF12763.2 ETO08814.1 - 1e-12 47.6 0.3 3.1e-12 46.1 0.0 1.9 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 ETO08814.1 - 0.022 14.0 0.0 0.056 12.7 0.0 1.8 1 0 0 1 1 1 0 EF hand HSP90 PF00183.13 ETO08815.1 - 1.3e-81 274.5 16.2 1.4e-69 234.8 8.7 3.2 1 1 1 2 2 2 2 Hsp90 protein Herpes_U15 PF05613.6 ETO08815.1 - 0.0095 16.2 6.7 0.02 15.2 1.9 2.7 2 0 0 2 2 2 1 Human herpesvirus U15 protein PilN PF05137.8 ETO08815.1 - 0.011 15.4 0.0 0.036 13.8 0.0 1.9 2 0 0 2 2 2 0 Fimbrial assembly protein (PilN) DUF619 PF04768.8 ETO08815.1 - 0.02 14.2 0.2 0.052 12.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF619) DUF2763 PF10961.3 ETO08815.1 - 1.7 9.0 3.3 3.6 8.0 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2763) Proteasome PF00227.21 ETO08816.1 - 2e-46 157.7 0.0 2.5e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit WD40 PF00400.27 ETO08817.1 - 3.1e-36 121.9 14.1 2.2e-11 43.1 0.3 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO08817.1 - 3.2e-06 25.5 7.7 0.09 10.8 0.3 3.9 1 1 3 4 4 4 4 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO08817.1 - 0.0038 17.0 2.4 0.042 13.6 0.4 2.6 1 1 1 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 ETO08817.1 - 0.0066 15.2 3.4 0.41 9.3 2.4 3.1 1 1 0 1 1 1 1 Nup133 N terminal like DUF1273 PF06908.6 ETO08817.1 - 0.077 12.6 0.3 0.12 12.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) Hira PF07569.6 ETO08817.1 - 0.16 11.1 2.5 0.41 9.8 0.2 2.3 1 1 2 3 3 3 0 TUP1-like enhancer of split TetM_leader PF08076.6 ETO08817.1 - 0.35 10.4 2.6 20 4.8 0.2 2.7 2 0 0 2 2 2 0 Tetracycline resistance determinant leader peptide CorA PF01544.13 ETO08820.1 - 6.5e-38 130.4 0.0 1.3e-37 129.4 0.0 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein HRDC PF00570.18 ETO08822.1 - 2.3e-09 36.8 0.0 6e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 HRDC domain JAB PF01398.16 ETO08822.1 - 0.021 14.5 0.2 0.23 11.2 0.1 2.2 1 1 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease LRR_4 PF12799.2 ETO08823.1 - 5.9e-09 35.3 2.8 8.1e-07 28.5 0.1 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETO08823.1 - 9.1e-08 31.1 3.2 0.43 10.7 0.0 5.0 4 1 0 4 4 4 3 Leucine Rich Repeat LRR_8 PF13855.1 ETO08823.1 - 6e-07 29.1 6.8 0.00022 20.9 0.3 2.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_7 PF13504.1 ETO08823.1 - 3.6e-05 23.2 6.9 0.62 10.4 0.0 5.7 5 1 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 ETO08823.1 - 0.00053 19.7 10.6 1.6 9.0 0.0 5.2 4 1 1 5 5 5 2 Leucine Rich repeat CHCH PF06747.8 ETO08823.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 CHCH domain DUF3688 PF12461.3 ETO08824.1 - 7.9 6.9 7.3 2.8 8.3 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3688) RhoGEF PF00621.15 ETO08826.1 - 0.0053 16.6 8.3 0.0053 16.6 5.8 2.7 2 1 0 2 2 2 1 RhoGEF domain GHL13 PF14883.1 ETO08826.1 - 0.01 15.0 2.2 0.021 14.0 1.5 1.5 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 MoCF_biosynth PF00994.19 ETO08826.1 - 0.16 11.4 0.0 0.34 10.2 0.0 1.5 1 0 0 1 1 1 0 Probable molybdopterin binding domain Syntaxin-6_N PF09177.6 ETO08826.1 - 3.6 8.0 18.5 2.8 8.4 1.9 4.5 4 0 0 4 4 4 0 Syntaxin 6, N-terminal DUF4404 PF14357.1 ETO08826.1 - 6.6 7.2 7.9 18 5.8 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Hexokinase_2 PF03727.11 ETO08827.1 - 2.1e-28 99.1 2.0 3.4e-14 52.6 0.0 3.0 1 1 2 3 3 3 3 Hexokinase DUF4280 PF14107.1 ETO08828.1 - 0.0093 16.2 1.6 0.0093 16.2 1.1 2.5 2 1 1 3 3 3 1 Domain of unknown function (DUF4280) zf-MYND PF01753.13 ETO08828.1 - 0.14 12.0 13.0 0.25 11.2 9.0 1.4 1 0 0 1 1 1 0 MYND finger DUF2614 PF11023.3 ETO08828.1 - 9.1 6.1 10.6 1.7 8.4 2.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2614) RelA_SpoT PF04607.12 ETO08830.1 - 0.0026 17.7 1.4 0.0026 17.7 1.0 3.0 3 0 0 3 3 3 1 Region found in RelA / SpoT proteins CCDC-167 PF15188.1 ETO08831.1 - 0.012 15.4 6.4 0.19 11.7 4.5 2.0 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 SeqA PF03925.8 ETO08831.1 - 0.016 14.9 2.5 0.018 14.7 1.8 1.2 1 0 0 1 1 1 0 SeqA protein ComX PF05952.7 ETO08831.1 - 0.033 13.6 1.3 0.13 11.7 0.0 2.3 1 1 2 3 3 3 0 Bacillus competence pheromone ComX DUF4419 PF14388.1 ETO08831.1 - 0.18 10.9 4.4 0.22 10.7 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4419) DUF694 PF05107.7 ETO08831.1 - 0.45 9.6 3.2 0.57 9.3 2.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF694) DUF106 PF01956.11 ETO08831.1 - 0.7 9.4 4.7 0.91 9.0 3.3 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 AAA_23 PF13476.1 ETO08831.1 - 0.82 9.9 13.4 0.89 9.8 9.3 1.1 1 0 0 1 1 1 0 AAA domain PAF-AH_p_II PF03403.8 ETO08831.1 - 1.1 7.4 5.9 1.3 7.2 4.1 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II OmpH PF03938.9 ETO08831.1 - 4.1 7.3 11.3 5.2 6.9 7.8 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) 7tm_3 PF00003.17 ETO08832.1 - 2.3e-14 53.3 4.7 2.3e-14 53.3 3.3 1.6 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR PQQ PF01011.16 ETO08832.1 - 0.029 13.8 0.9 1.3 8.7 0.2 2.4 2 0 0 2 2 2 0 PQQ enzyme repeat EGF_2 PF07974.8 ETO08832.1 - 0.036 14.2 6.8 0.036 14.2 4.7 2.1 2 0 0 2 2 2 0 EGF-like domain DUF4149 PF13664.1 ETO08832.1 - 0.29 11.2 4.0 17 5.5 2.8 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) DUF4307 PF14155.1 ETO08832.1 - 1.2 8.9 4.0 1.3 8.8 0.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4307) 7tm_3 PF00003.17 ETO08833.1 - 0.15 11.3 11.4 0.22 10.8 7.8 1.4 1 1 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR Cation_efflux PF01545.16 ETO08833.1 - 0.24 10.4 3.8 0.27 10.2 2.2 1.4 1 1 0 1 1 1 0 Cation efflux family SieB PF14163.1 ETO08833.1 - 0.32 10.5 2.9 0.53 9.8 1.7 1.6 1 1 0 1 1 1 0 Superinfection exclusion protein B 7TM_GPCR_Srz PF10325.4 ETO08833.1 - 0.4 9.7 12.4 0.58 9.2 8.6 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srz DUF2254 PF10011.4 ETO08833.1 - 0.71 8.2 6.0 1.1 7.6 4.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) DUF2207 PF09972.4 ETO08833.1 - 5.5 5.4 9.2 8.5 4.8 6.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) EF-hand_4 PF12763.2 ETO08834.1 - 3.8e-05 23.3 0.0 6.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Auto_anti-p27 PF06677.7 ETO08835.1 - 1.3e-06 28.0 0.5 2.1e-06 27.3 0.3 1.3 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF605 PF04652.11 ETO08835.1 - 0.053 12.9 23.1 0.063 12.6 16.0 1.1 1 0 0 1 1 1 0 Vta1 like Dicty_REP PF05086.7 ETO08835.1 - 6.9 4.2 6.8 8.7 3.9 4.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein WD40 PF00400.27 ETO08836.1 - 4.5e-29 99.2 6.8 2.4e-14 52.5 0.3 4.9 4 1 0 4 4 4 3 WD domain, G-beta repeat PD40 PF07676.7 ETO08836.1 - 0.007 16.0 0.4 14 5.4 0.0 3.9 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO08836.1 - 0.021 13.5 0.3 1.3 7.7 0.2 2.3 1 1 0 1 1 1 0 Nup133 N terminal like DPPIV_N PF00930.16 ETO08836.1 - 0.034 12.7 0.0 0.19 10.2 0.0 2.2 1 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Kelch_1 PF01344.20 ETO08836.1 - 0.066 12.7 1.5 0.29 10.7 0.0 2.8 3 0 0 3 3 3 0 Kelch motif Nup160 PF11715.3 ETO08836.1 - 0.079 11.0 0.4 0.35 8.9 0.2 2.0 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO08836.1 - 0.2 11.9 1.1 11 6.3 0.0 3.9 4 0 0 4 4 4 0 Kelch motif WD40 PF00400.27 ETO08837.1 - 1.9e-33 113.0 0.1 2.1e-13 49.5 0.0 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO08837.1 - 9.5e-07 27.4 0.1 2.1e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Cytochrome D1 heme domain eIF2A PF08662.6 ETO08837.1 - 1.3e-05 24.9 0.1 0.019 14.6 0.0 2.5 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 ETO08837.1 - 0.00016 21.2 0.0 0.002 17.6 0.0 2.0 1 1 0 1 1 1 1 PQQ-like domain Nup160 PF11715.3 ETO08837.1 - 0.00052 18.2 0.0 0.00062 18.0 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO08837.1 - 0.0025 16.6 0.1 0.11 11.1 0.0 2.2 1 1 1 2 2 2 1 Nup133 N terminal like Coatomer_WDAD PF04053.9 ETO08837.1 - 0.018 13.8 0.0 2 7.1 0.0 2.1 1 1 1 2 2 2 0 Coatomer WD associated region SGL PF08450.7 ETO08837.1 - 0.018 14.4 0.0 0.39 10.0 0.0 2.0 1 1 1 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region VID27 PF08553.5 ETO08837.1 - 0.025 12.8 0.2 0.7 8.0 0.0 2.0 1 1 1 2 2 2 0 VID27 cytoplasmic protein Nop10p PF04135.7 ETO08837.1 - 0.31 10.8 1.8 13 5.6 0.1 2.6 3 0 0 3 3 3 0 Nucleolar RNA-binding protein, Nop10p family WD40 PF00400.27 ETO08838.1 - 1.2e-35 120.1 1.4 7.3e-11 41.5 0.3 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO08838.1 - 2.3e-07 29.3 5.6 0.0094 14.1 0.1 3.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO08838.1 - 3.8e-07 29.1 7.7 0.00032 19.5 0.2 3.0 1 1 1 2 2 2 2 Nup133 N terminal like Ras PF00071.17 ETO08839.1 - 9.4e-24 83.6 0.1 1.1e-23 83.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO08839.1 - 6.3e-06 26.6 0.0 9.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 ETO08839.1 - 0.00032 20.2 0.0 0.00042 19.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 ETO08839.1 - 0.00043 19.5 0.1 0.00064 19.0 0.1 1.2 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETO08839.1 - 0.0015 18.4 0.0 0.0024 17.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase PIG-H PF10181.4 ETO08839.1 - 0.12 12.0 0.2 0.59 9.8 0.0 2.1 2 0 0 2 2 2 0 GPI-GlcNAc transferase complex, PIG-H component WD40 PF00400.27 ETO08840.1 - 2.6e-43 144.3 6.3 7.3e-12 44.6 0.1 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO08840.1 - 8.2e-07 27.5 0.9 0.016 13.3 0.0 3.4 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO08840.1 - 0.00025 19.9 4.6 0.78 8.4 0.1 3.5 1 1 2 3 3 3 3 Nup133 N terminal like PQQ_2 PF13360.1 ETO08840.1 - 0.00072 19.0 0.2 0.012 15.0 0.1 2.4 2 1 0 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO08840.1 - 0.0051 15.1 0.2 0.17 10.1 0.1 2.2 1 1 0 1 1 1 1 Cytochrome D1 heme domain PD40 PF07676.7 ETO08840.1 - 0.0065 16.1 1.0 1.2 8.9 0.0 3.6 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat DWNN PF08783.6 ETO08840.1 - 0.083 12.8 0.3 3.4 7.6 0.0 2.4 2 0 0 2 2 2 0 DWNN domain Proteasome_A_N PF10584.4 ETO08840.1 - 0.17 11.1 0.9 1.6 8.1 0.0 2.6 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature HEAT_2 PF13646.1 ETO08841.1 - 8.9e-06 25.9 0.0 5.2e-05 23.4 0.0 2.2 2 1 0 2 2 2 1 HEAT repeats HEAT PF02985.17 ETO08841.1 - 1.3e-05 24.8 0.0 0.00043 20.1 0.0 2.7 2 0 0 2 2 2 1 HEAT repeat HEAT_EZ PF13513.1 ETO08841.1 - 0.00061 20.2 0.0 0.0019 18.5 0.0 1.9 2 0 0 2 2 2 1 HEAT-like repeat Cnd1 PF12717.2 ETO08841.1 - 0.0017 18.2 3.6 0.011 15.6 2.5 2.5 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 NLE PF08154.7 ETO08841.1 - 0.0052 16.7 4.1 0.99 9.4 0.1 3.4 4 1 0 4 4 4 2 NLE (NUC135) domain DUF3554 PF12074.3 ETO08841.1 - 0.014 14.8 1.4 0.075 12.4 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3554) Activator-TraM PF11657.3 ETO08841.1 - 0.016 14.6 0.6 0.063 12.7 0.1 2.1 1 1 0 2 2 2 0 Transcriptional activator TraM Vac14_Fab1_bd PF12755.2 ETO08841.1 - 0.041 14.2 0.0 0.27 11.6 0.0 2.2 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region Kinase-PPPase PF03618.9 ETO08841.1 - 0.045 13.2 0.1 1 8.7 0.0 2.0 1 1 1 2 2 2 0 Kinase/pyrophosphorylase TAN PF11640.3 ETO08841.1 - 0.093 12.4 4.8 0.25 11.0 0.8 3.2 1 1 1 2 2 2 0 Telomere-length maintenance and DNA damage repair Gag_p24 PF00607.15 ETO08841.1 - 0.1 12.1 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) DUF4284 PF14112.1 ETO08841.1 - 0.14 12.6 3.1 0.3 11.5 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4284) XkdW PF09636.5 ETO08841.1 - 1.6 8.6 5.9 8.7 6.2 0.1 3.5 1 1 2 4 4 4 0 XkdW protein DUF2873 PF11395.3 ETO08842.1 - 0.046 13.2 1.3 0.046 13.2 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2873) COX4_pro PF03626.9 ETO08842.1 - 0.073 13.1 1.0 0.11 12.5 0.7 1.3 1 0 0 1 1 1 0 Prokaryotic Cytochrome C oxidase subunit IV COX4_pro_2 PF07835.7 ETO08842.1 - 0.44 10.5 4.1 13 5.8 0.9 2.5 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV eRF1_3 PF03465.10 ETO08843.1 - 9.5e-07 29.0 0.2 9.3e-06 25.8 0.1 2.2 1 1 0 1 1 1 1 eRF1 domain 3 PHD PF00628.24 ETO08844.1 - 2.6e-10 39.8 6.2 8.1e-10 38.2 4.3 1.9 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 ETO08844.1 - 0.009 16.1 2.7 0.009 16.1 1.9 2.4 2 0 0 2 2 2 1 PHD-like zinc-binding domain Ras PF00071.17 ETO08845.1 - 1.4e-30 105.8 0.0 2e-28 98.8 0.0 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 ETO08845.1 - 1.5e-06 28.6 0.0 6.5e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO08845.1 - 0.00033 19.9 0.2 0.13 11.4 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO08845.1 - 0.01 15.3 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Lipase_GDSL_3 PF14606.1 ETO08845.1 - 0.064 12.9 0.0 0.17 11.6 0.0 1.6 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family XkdN PF08890.6 ETO08845.1 - 0.069 12.8 1.2 4.4 7.0 0.0 2.1 2 0 0 2 2 2 0 Phage XkdN-like protein RVT_1 PF00078.22 ETO08846.1 - 1.3e-36 126.0 0.3 3.1e-36 124.7 0.2 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 ETO08846.1 - 3.7e-19 68.4 1.3 1.4e-18 66.6 0.9 2.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 ETO08846.1 - 1.7e-17 64.0 0.0 5.8e-17 62.2 0.0 2.0 2 0 0 2 2 2 1 RNase H zf-RVT PF13966.1 ETO08846.1 - 7.9e-05 22.8 0.6 7.9e-05 22.8 0.4 3.2 4 0 0 4 4 4 1 zinc-binding in reverse transcriptase Pyridoxal_deC PF00282.14 ETO08847.1 - 1.1e-18 66.9 0.0 1.8e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain PARP PF00644.15 ETO08848.1 - 7.6e-09 35.2 0.0 7.6e-09 35.2 0.0 3.4 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain IBR PF01485.16 ETO08848.1 - 0.0048 16.7 10.3 0.016 15.1 7.1 1.9 1 0 0 1 1 1 1 IBR domain CDC45 PF02724.9 ETO08848.1 - 0.13 10.3 46.2 0.13 10.2 12.0 2.1 2 0 0 2 2 2 0 CDC45-like protein Cwf_Cwc_15 PF04889.7 ETO08848.1 - 0.33 10.6 59.1 0.069 12.8 14.9 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Daxx PF03344.10 ETO08848.1 - 1.2 7.4 38.8 0.76 8.1 9.3 2.1 2 0 0 2 2 2 0 Daxx Family C1_4 PF07975.7 ETO08848.1 - 1.3 9.0 9.4 6.5 6.8 6.5 2.3 1 0 0 1 1 1 0 TFIIH C1-like domain DUF1510 PF07423.6 ETO08848.1 - 1.6 8.0 55.5 0.44 9.8 14.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Arf PF00025.16 ETO08849.1 - 0.023 13.9 0.0 0.034 13.3 0.0 1.4 1 1 0 1 1 1 0 ADP-ribosylation factor family DENN PF02141.16 ETO08851.1 - 1.7e-41 141.9 3.7 2e-33 115.6 0.3 2.0 1 1 1 2 2 2 2 DENN (AEX-3) domain Inp1 PF12634.2 ETO08852.1 - 0.6 9.7 3.4 0.4 10.3 0.1 2.3 2 0 0 2 2 2 0 Inheritance of peroxisomes protein 1 Ank_2 PF12796.2 ETO08853.1 - 4.5e-17 62.1 0.1 7.7e-08 32.5 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO08853.1 - 8.4e-08 32.5 0.0 0.047 14.2 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO08853.1 - 1.2e-07 31.2 0.2 0.13 12.6 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.25 ETO08853.1 - 2.9e-07 29.9 0.0 0.01 15.5 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 ETO08853.1 - 0.00096 19.3 0.0 0.16 12.2 0.0 3.3 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Kelch_1 PF01344.20 ETO08854.1 - 0.0001 21.7 1.5 0.0086 15.6 0.3 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO08854.1 - 0.00078 19.1 2.9 0.87 9.4 0.0 3.0 3 1 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETO08854.1 - 0.00084 19.0 0.5 1.9 8.3 0.0 3.5 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO08854.1 - 0.0092 16.1 2.1 1.3 9.2 0.4 2.8 1 1 1 2 2 2 1 Kelch motif Kelch_5 PF13854.1 ETO08854.1 - 0.012 15.5 2.8 0.18 11.8 0.5 2.8 3 0 0 3 3 3 0 Kelch motif Kelch_3 PF13415.1 ETO08854.1 - 0.067 13.3 0.0 0.81 9.9 0.0 2.8 5 0 0 5 5 5 0 Galactose oxidase, central domain DUF1725 PF08333.6 ETO08854.1 - 0.087 12.1 0.1 0.24 10.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) Beta_helix PF13229.1 ETO08855.1 - 0.092 12.4 17.9 0.45 10.2 12.4 1.9 1 1 0 1 1 1 0 Right handed beta helix region DUF756 PF05506.7 ETO08855.1 - 0.24 11.9 0.9 0.37 11.3 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF756) DUF4416 PF14385.1 ETO08856.1 - 0.029 14.0 0.1 0.041 13.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4416) BPL_N PF09825.4 ETO08857.1 - 1.3e-42 145.9 0.2 1.9e-42 145.3 0.1 1.2 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal Bac_small_YrzI PF09501.5 ETO08857.1 - 2.5 8.0 5.3 8 6.4 3.7 1.9 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) Cytomega_UL84 PF06284.6 ETO08858.1 - 1.1 7.5 5.2 1.6 7.0 3.6 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein RR_TM4-6 PF06459.7 ETO08858.1 - 4.8 6.9 13.5 6.9 6.4 9.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.1 ETO08858.1 - 5.6 6.6 8.8 14 5.3 4.7 2.1 2 0 0 2 2 2 0 Protein Family FAM60A POX PF07526.6 ETO08858.1 - 6.2 7.0 7.8 5.2 7.2 4.3 1.7 2 0 0 2 2 2 0 Associated with HOX WD40 PF00400.27 ETO08860.1 - 8.9e-27 91.9 9.8 1.1e-09 37.7 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO08860.1 - 8.1e-07 27.5 1.1 0.091 10.8 0.0 3.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 DUF3654 PF12376.3 ETO08860.1 - 0.088 12.6 0.3 0.34 10.7 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3654) MHC_II_beta PF00969.14 ETO08860.1 - 0.21 11.6 3.9 2.4 8.2 0.4 2.7 3 0 0 3 3 3 0 Class II histocompatibility antigen, beta domain Kelch_6 PF13964.1 ETO08861.1 - 5.7e-06 26.2 0.1 0.54 10.5 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 ETO08861.1 - 0.00044 20.1 0.7 1.3 9.0 0.0 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 ETO08861.1 - 0.00097 18.6 0.6 0.069 12.6 0.0 3.3 3 0 0 3 3 3 1 Kelch motif Nucleoporin_C PF03177.9 ETO08861.1 - 0.0074 14.8 0.0 0.011 14.2 0.0 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal RVT_1 PF00078.22 ETO08862.1 - 0.013 14.9 0.6 0.089 12.1 0.1 2.0 1 1 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3198 PF11433.3 ETO08862.1 - 0.025 14.4 0.1 0.048 13.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3198) Cyclin_N PF00134.18 ETO08863.1 - 2.3e-08 33.6 0.7 2.3e-08 33.6 0.5 2.2 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 ETO08863.1 - 0.0066 16.3 5.0 0.0087 15.9 1.3 2.8 2 1 1 3 3 3 1 Cyclin, C-terminal domain PI3_PI4_kinase PF00454.22 ETO08865.1 - 3.2e-28 98.8 0.1 4.7e-28 98.2 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 ETO08865.1 - 6.4e-08 31.8 0.4 6.4e-08 31.8 0.3 1.7 2 0 0 2 2 2 1 FATC domain NPHI_C PF08469.5 ETO08865.1 - 0.066 13.1 2.6 0.17 11.8 0.1 2.6 2 2 0 2 2 2 0 Nucleoside triphosphatase I C-terminal NUC194 PF08163.7 ETO08866.1 - 1.8e-42 145.6 0.2 5.7e-41 140.6 0.1 2.6 1 1 0 1 1 1 1 NUC194 domain FAT PF02259.18 ETO08866.1 - 3.3e-06 26.3 16.9 3.3e-06 26.3 11.7 3.3 4 1 0 4 4 4 1 FAT domain VKOR PF07884.9 ETO08869.1 - 0.038 13.8 2.3 0.058 13.2 1.6 1.2 1 0 0 1 1 1 0 Vitamin K epoxide reductase family WD40 PF00400.27 ETO08871.1 - 7.3e-30 101.7 12.9 1.4e-11 43.7 0.1 4.8 6 0 0 6 6 6 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 ETO08871.1 - 0.00024 20.8 1.5 0.014 15.2 0.1 2.6 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 ETO08871.1 - 0.00039 18.6 0.4 0.15 10.1 0.2 2.9 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO08871.1 - 0.021 13.5 7.1 3.1 6.4 4.5 3.0 1 1 0 1 1 1 0 Nup133 N terminal like RabGGT_insert PF07711.6 ETO08871.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Rab geranylgeranyl transferase alpha-subunit, insert domain WD40 PF00400.27 ETO08873.1 - 9.1e-37 123.6 0.2 4.5e-12 45.3 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 ETO08873.1 - 7.5e-09 35.5 0.3 0.00058 19.6 0.0 3.3 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO08873.1 - 2.6e-07 30.1 1.5 0.23 11.1 0.0 5.0 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Kelch_6 PF13964.1 ETO08873.1 - 1.6e-05 24.8 2.1 0.012 15.7 0.4 2.9 1 1 1 2 2 2 2 Kelch motif Cytochrom_D1 PF02239.11 ETO08873.1 - 0.00016 20.1 0.0 0.1 10.8 0.0 2.5 1 1 2 3 3 3 3 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 ETO08873.1 - 0.00074 18.4 0.2 0.0013 17.6 0.1 1.4 1 0 0 1 1 1 1 Coatomer WD associated region Nup160 PF11715.3 ETO08873.1 - 0.0011 17.2 0.1 0.0037 15.4 0.1 1.9 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Kelch_1 PF01344.20 ETO08873.1 - 0.0019 17.6 1.3 0.01 15.3 0.7 2.2 2 0 0 2 2 2 1 Kelch motif Phage_Gp23 PF10669.4 ETO08873.1 - 0.0072 16.4 4.1 0.018 15.1 2.8 1.7 1 0 0 1 1 1 1 Protein gp23 (Bacteriophage A118) Kelch_4 PF13418.1 ETO08873.1 - 0.013 15.2 0.7 4.3 7.1 0.3 2.6 2 0 0 2 2 2 0 Galactose oxidase, central domain Nucleoporin_N PF08801.6 ETO08873.1 - 0.019 13.7 3.7 0.11 11.2 1.0 2.9 1 1 1 2 2 2 0 Nup133 N terminal like Proteasome_A_N PF10584.4 ETO08873.1 - 0.023 14.0 4.6 12 5.3 0.0 4.7 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature B_lectin PF01453.19 ETO08873.1 - 0.063 13.1 0.2 0.97 9.3 0.1 2.3 1 1 2 3 3 2 0 D-mannose binding lectin Kelch_5 PF13854.1 ETO08873.1 - 0.35 10.8 2.4 0.59 10.1 0.7 2.0 2 0 0 2 2 2 0 Kelch motif WD40 PF00400.27 ETO08874.1 - 9.3e-17 60.2 5.7 1.7e-10 40.3 0.0 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO08874.1 - 0.008 14.3 0.1 1.2 7.1 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO08874.1 - 0.11 11.2 0.2 2.6 6.7 0.0 2.0 1 1 1 2 2 2 0 Nup133 N terminal like OmpH PF03938.9 ETO08875.1 - 0.0049 16.8 5.0 0.015 15.2 3.5 1.9 1 1 0 1 1 1 1 Outer membrane protein (OmpH-like) Tyrosinase PF00264.15 ETO08875.1 - 0.15 12.1 0.3 0.82 9.7 0.0 1.9 2 0 0 2 2 2 0 Common central domain of tyrosinase DUF948 PF06103.6 ETO08875.1 - 0.27 11.1 10.6 0.49 10.2 2.0 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) ApoO PF09769.4 ETO08875.1 - 0.53 9.9 2.6 5.4 6.7 0.7 2.8 2 1 0 2 2 2 0 Apolipoprotein O Tho2 PF11262.3 ETO08875.1 - 0.64 9.0 8.5 0.38 9.7 3.9 1.9 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF3106 PF11304.3 ETO08875.1 - 2.1 8.8 14.6 6.9 7.1 0.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3106) DUF883 PF05957.8 ETO08875.1 - 5.8 7.3 15.5 5.1 7.5 1.5 4.1 2 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) HALZ PF02183.13 ETO08875.1 - 6.1 6.6 15.0 0.72 9.6 2.7 4.1 3 1 0 3 3 3 0 Homeobox associated leucine zipper RPEL PF02755.10 ETO08876.1 - 2e-07 30.1 13.8 0.00029 20.0 0.2 4.1 4 0 0 4 4 4 3 RPEL repeat PsaD PF02531.11 ETO08876.1 - 0.046 12.9 0.9 0.063 12.4 0.6 1.2 1 0 0 1 1 1 0 PsaD Secretin_N_2 PF07655.8 ETO08876.1 - 0.25 11.7 13.2 0.46 10.9 9.1 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain RPEL PF02755.10 ETO08877.1 - 7.3e-05 21.9 7.0 0.01 15.1 0.7 3.5 3 1 0 3 3 3 3 RPEL repeat MACPF PF01823.14 ETO08877.1 - 0.41 10.2 9.5 0.11 12.1 4.7 1.5 2 0 0 2 2 2 0 MAC/Perforin domain TCP PF03634.8 ETO08877.1 - 0.76 10.1 6.6 1.8 8.9 4.6 1.6 1 0 0 1 1 1 0 TCP family transcription factor Nop14 PF04147.7 ETO08878.1 - 7.7e-50 169.6 35.0 1.9e-49 168.4 24.3 1.6 1 1 0 1 1 1 1 Nop14-like family eIF-3c_N PF05470.7 ETO08878.1 - 6 4.8 26.9 0.0081 14.3 10.6 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Nop14 PF04147.7 ETO08880.1 - 1.5e-13 49.6 25.8 7.3e-11 40.7 17.9 2.0 1 1 0 1 1 1 1 Nop14-like family Musclin PF11037.3 ETO08880.1 - 0.00064 19.3 0.0 0.0016 18.0 0.0 1.7 1 0 0 1 1 1 1 Insulin-resistance promoting peptide in skeletal muscle DUF3969 PF13108.1 ETO08880.1 - 0.037 13.6 0.4 0.39 10.3 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3969) DUF2802 PF10975.3 ETO08880.1 - 0.27 10.9 5.8 3.2 7.5 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF2802) Suppressor_APC PF11414.3 ETO08880.1 - 0.59 9.9 7.7 4.2 7.2 0.1 3.8 3 1 0 4 4 4 0 Adenomatous polyposis coli tumour suppressor protein DUF4248 PF14053.1 ETO08881.1 - 0.097 12.2 1.9 0.31 10.6 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4248) DUF2854 PF11016.3 ETO08881.1 - 4.8 6.7 10.5 1.4 8.3 0.2 3.1 2 2 0 3 3 3 0 Protein of unknown function (DUF2854) CENP-F_leu_zip PF10473.4 ETO08882.1 - 0.0021 17.9 8.2 0.0021 17.9 5.7 2.1 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.3 ETO08882.1 - 0.015 14.9 16.5 0.26 11.0 1.8 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding SlyX PF04102.7 ETO08882.1 - 0.029 14.7 13.9 0.11 12.9 2.0 2.8 1 1 0 2 2 2 0 SlyX Striatin PF08232.7 ETO08882.1 - 0.12 12.7 10.6 0.081 13.2 6.0 1.8 1 1 0 1 1 1 0 Striatin family Reo_sigmaC PF04582.7 ETO08882.1 - 0.2 10.7 1.4 0.42 9.7 1.0 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein IncA PF04156.9 ETO08882.1 - 0.44 10.1 16.5 1.5 8.4 10.9 2.0 1 1 1 2 2 2 0 IncA protein DUF3450 PF11932.3 ETO08882.1 - 0.65 9.2 11.6 1.2 8.3 7.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Cortex-I_coil PF09304.5 ETO08882.1 - 1.2 9.2 17.0 0.28 11.2 2.9 2.7 1 1 1 2 2 2 0 Cortexillin I, coiled coil DUF641 PF04859.7 ETO08882.1 - 1.9 8.2 15.8 3.6 7.3 3.5 3.0 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) CENP-Q PF13094.1 ETO08882.1 - 3.6 7.5 15.4 6.2 6.8 6.4 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3552 PF12072.3 ETO08882.1 - 8 5.6 20.4 0.1 11.7 2.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) TMF_DNA_bd PF12329.3 ETO08882.1 - 8.7 6.2 20.9 0.14 12.0 4.2 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 ETO08882.1 - 9.9 5.9 20.9 3.3 7.4 6.2 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Thy1 PF02511.10 ETO08883.1 - 0.0065 15.8 0.5 0.017 14.4 0.3 1.7 1 1 0 1 1 1 1 Thymidylate synthase complementing protein Tox-REase-3 PF15647.1 ETO08883.1 - 0.026 14.3 3.3 0.03 14.1 0.2 2.1 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 3 YccV-like PF08755.6 ETO08883.1 - 8.2 6.4 7.0 2.8 7.9 0.1 2.8 1 1 2 3 3 3 0 Hemimethylated DNA-binding protein YccV like DNA_pol_B PF00136.16 ETO08884.1 - 5.1e-140 467.3 3.4 7e-140 466.8 2.3 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 ETO08884.1 - 2e-76 256.9 0.0 3.9e-76 256.0 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 ETO08884.1 - 1.2e-20 73.2 6.3 3.1e-20 71.9 4.4 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_A_exo1 PF01612.15 ETO08884.1 - 0.0036 16.8 0.1 3.3 7.1 0.0 2.5 2 0 0 2 2 2 2 3'-5' exonuclease zf-RING-like PF08746.6 ETO08884.1 - 2 8.4 8.6 0.033 14.1 0.6 2.1 2 0 0 2 2 2 0 RING-like domain DUF2283 PF10049.4 ETO08885.1 - 0.034 13.9 1.4 0.074 12.9 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2283) SPX PF03105.14 ETO08886.1 - 0.027 14.2 3.3 0.034 13.9 2.3 1.1 1 0 0 1 1 1 0 SPX domain CENP-Q PF13094.1 ETO08886.1 - 0.046 13.7 12.4 0.17 11.8 8.6 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DivIC PF04977.10 ETO08886.1 - 0.46 10.0 9.9 0.16 11.4 3.2 2.3 2 1 0 2 2 2 0 Septum formation initiator UBN2_3 PF14244.1 ETO08886.1 - 0.58 9.7 4.7 0.21 11.1 1.7 1.4 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type DUF4407 PF14362.1 ETO08886.1 - 0.58 9.0 3.0 0.75 8.6 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Retrotrans_gag PF03732.12 ETO08886.1 - 0.61 10.1 3.9 0.19 11.8 1.1 1.4 2 0 0 2 2 2 0 Retrotransposon gag protein Gon7 PF08738.5 ETO08886.1 - 0.9 9.5 8.2 0.81 9.7 5.1 1.4 1 1 0 1 1 1 0 Gon7 family bZIP_1 PF00170.16 ETO08886.1 - 1.1 9.2 6.3 0.5 10.3 1.6 2.0 2 0 0 2 2 2 0 bZIP transcription factor DUF724 PF05266.9 ETO08886.1 - 1.1 8.8 9.9 0.51 9.9 4.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF724) PolyA_pol PF01743.15 ETO08886.1 - 1.8 8.8 4.2 2.3 8.4 2.5 1.5 1 1 1 2 2 2 0 Poly A polymerase head domain End3 PF12761.2 ETO08886.1 - 1.9 8.0 9.0 3.5 7.2 6.2 1.5 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 KLRAQ PF10205.4 ETO08886.1 - 2 8.5 8.3 0.4 10.7 2.9 1.7 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein DUF3373 PF11853.3 ETO08886.1 - 3.3 6.1 5.1 3.2 6.1 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Fib_alpha PF08702.5 ETO08886.1 - 3.7 7.6 10.1 6.2 6.9 7.0 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family HALZ PF02183.13 ETO08886.1 - 5.5 6.7 7.3 8.4 6.2 0.3 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper Spc24 PF08286.6 ETO08886.1 - 6.7 6.4 10.5 2.5 7.8 4.8 1.8 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 EMP24_GP25L PF01105.19 ETO08886.1 - 8.9 5.9 8.6 12 5.5 3.5 2.0 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD TMF_DNA_bd PF12329.3 ETO08886.1 - 9.4 6.1 14.3 6.9 6.5 6.1 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SAC3_GANP PF03399.11 ETO08887.1 - 0.062 12.8 0.3 0.069 12.6 0.2 1.0 1 0 0 1 1 1 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family SAS4 PF15460.1 ETO08887.1 - 0.069 13.0 0.1 0.079 12.8 0.1 1.2 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 NMT_C PF02799.10 ETO08887.1 - 0.075 12.3 0.2 0.078 12.3 0.1 1.1 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain WD40 PF00400.27 ETO08888.1 - 9e-08 31.7 6.4 0.00021 21.0 0.1 4.4 4 1 0 4 4 4 2 WD domain, G-beta repeat YcxB PF14317.1 ETO08888.1 - 0.0044 16.2 0.2 0.0089 15.2 0.1 1.6 1 0 0 1 1 1 1 YcxB-like protein PsiF_repeat PF07769.9 ETO08888.1 - 0.062 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 psiF repeat GEMIN8 PF15348.1 ETO08889.1 - 0.0044 17.0 0.4 0.0051 16.8 0.3 1.1 1 0 0 1 1 1 1 Gemini of Cajal bodies-associated protein 8 DUF2956 PF11169.3 ETO08889.1 - 0.016 15.1 3.6 0.025 14.5 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) NinG PF05766.7 ETO08889.1 - 0.029 14.1 6.2 0.038 13.7 4.3 1.1 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein Protocadherin PF08374.6 ETO08889.1 - 0.039 13.6 0.4 0.048 13.2 0.3 1.2 1 0 0 1 1 1 0 Protocadherin FAM176 PF14851.1 ETO08889.1 - 0.04 13.5 0.8 0.057 13.1 0.6 1.2 1 0 0 1 1 1 0 FAM176 family BLVR PF06375.6 ETO08889.1 - 0.043 13.6 11.2 0.076 12.8 7.8 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Peptidase_S49_N PF08496.5 ETO08889.1 - 0.044 13.5 3.2 0.057 13.2 2.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal YajC PF02699.10 ETO08889.1 - 0.14 11.8 0.3 0.27 10.9 0.2 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit Eapp_C PF10238.4 ETO08889.1 - 0.15 11.9 6.8 0.13 12.1 3.9 1.5 1 1 1 2 2 2 0 E2F-associated phosphoprotein DUSP PF06337.7 ETO08889.1 - 1.3 9.4 7.3 43 4.5 5.1 2.2 1 1 0 1 1 1 0 DUSP domain DUF2457 PF10446.4 ETO08889.1 - 1.6 7.4 8.6 2 7.0 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PBP1_TM PF14812.1 ETO08889.1 - 2.9 8.2 9.7 4.5 7.6 6.7 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UPF0542 PF15086.1 ETO08889.1 - 4.3 7.1 9.6 9.8 5.9 6.7 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 Vps54 PF07928.7 ETO08890.1 - 0.0099 16.0 0.3 0.035 14.2 0.0 2.0 1 1 1 2 2 2 1 Vps54-like protein Oscp1 PF10188.4 ETO08890.1 - 0.084 12.6 0.6 0.98 9.2 0.1 2.1 2 0 0 2 2 2 0 Organic solute transport protein 1 Prok-E2_E PF14462.1 ETO08890.1 - 0.1 12.1 0.1 0.22 11.1 0.1 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family E Beta_helix PF13229.1 ETO08891.1 - 0.094 12.4 4.0 0.12 12.0 2.8 1.3 1 0 0 1 1 1 0 Right handed beta helix region PPR_2 PF13041.1 ETO08895.1 - 0.0079 16.1 0.1 0.022 14.7 0.1 1.7 1 0 0 1 1 1 1 PPR repeat family PPR PF01535.15 ETO08895.1 - 0.027 14.4 0.1 0.074 13.0 0.0 1.8 1 0 0 1 1 1 0 PPR repeat Ran_BP1 PF00638.13 ETO08896.1 - 1.6e-05 24.9 1.0 2.1e-05 24.5 0.1 1.7 2 0 0 2 2 2 1 RanBP1 domain DUF3894 PF13033.1 ETO08898.1 - 0.52 10.3 6.6 0.85 9.6 4.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3894) DUF3275 PF11679.3 ETO08899.1 - 0.013 15.1 0.8 0.019 14.6 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) DUF1312 PF07009.6 ETO08900.1 - 0.026 14.3 4.7 0.17 11.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1312) UPF0542 PF15086.1 ETO08900.1 - 1.3 8.8 6.7 0.17 11.5 0.7 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 UCH PF00443.24 ETO08901.1 - 6.3e-06 25.5 8.2 2.6e-05 23.4 5.7 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO08901.1 - 0.00026 20.5 0.0 0.00026 20.5 0.0 2.1 1 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF2894 PF11445.3 ETO08901.1 - 0.6 10.3 4.3 1.1 9.4 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) GET2 PF08690.5 ETO08901.1 - 2.9 7.0 10.2 4.4 6.4 7.1 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 EF_TS PF00889.14 ETO08902.1 - 0.024 13.9 0.2 0.027 13.7 0.1 1.2 1 0 0 1 1 1 0 Elongation factor TS BNR_assoc_N PF14873.1 ETO08902.1 - 0.19 11.5 3.0 0.31 10.7 2.0 1.5 1 1 0 1 1 1 0 N-terminal domain of BNR-repeat neuraminidase zf-CCHC PF00098.18 ETO08904.1 - 0.0061 16.4 1.6 0.0061 16.4 1.1 2.5 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC_4 PF14392.1 ETO08904.1 - 0.0098 15.5 7.8 0.44 10.2 0.6 2.7 1 1 1 2 2 2 2 Zinc knuckle Brr6_like_C_C PF10104.4 ETO08904.1 - 0.93 9.0 6.2 1.5 8.3 4.3 1.4 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain zf-C4pol PF14260.1 ETO08904.1 - 5.5 7.0 13.2 3.3 7.7 5.6 2.8 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Maelstrom PF13017.1 ETO08905.1 - 0.018 14.5 0.1 0.022 14.2 0.1 1.2 1 0 0 1 1 1 0 piRNA pathway germ-plasm component Mucin PF01456.12 ETO08906.1 - 0.03 14.1 10.1 0.05 13.3 7.0 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Med3 PF11593.3 ETO08906.1 - 2.7 7.1 17.6 0.35 10.0 1.6 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Jnk-SapK_ap_N PF09744.4 ETO08906.1 - 8.9 6.2 13.1 1.1 9.1 6.3 1.5 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 BTB PF00651.26 ETO08907.1 - 2.4e-08 33.9 0.2 6.8e-08 32.4 0.2 1.7 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 ETO08907.1 - 1.5e-07 31.1 0.7 1.5e-07 31.1 0.5 3.2 4 0 0 4 4 4 1 BTB And C-terminal Kelch Tol_Tol_Ttg2 PF05494.7 ETO08907.1 - 0.025 14.1 0.1 0.064 12.8 0.1 1.6 1 0 0 1 1 1 0 Toluene tolerance, Ttg2 WD40 PF00400.27 ETO08908.1 - 2.1e-62 204.9 24.8 1.3e-12 47.0 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO08908.1 - 5.2e-12 44.6 9.1 0.0027 15.9 1.1 5.6 1 1 4 5 5 5 5 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO08908.1 - 4e-06 27.0 2.0 1.6e-05 25.1 1.4 2.1 1 0 0 1 1 1 1 TRAF-type zinc finger DUF3601 PF12208.3 ETO08908.1 - 0.016 15.1 2.1 11 6.0 0.0 4.2 3 1 0 3 3 3 0 Domain of unknown function (DUF3601) ABC2_membrane_3 PF12698.2 ETO08909.1 - 5e-44 150.7 71.7 8.9e-38 130.1 13.8 3.6 3 0 0 3 3 3 2 ABC-2 family transporter protein ABC_tran PF00005.22 ETO08909.1 - 4.7e-43 146.7 0.9 3.3e-20 72.7 0.0 3.8 4 0 0 4 4 3 2 ABC transporter AAA_21 PF13304.1 ETO08909.1 - 1.9e-19 70.7 1.0 3.1e-07 30.6 0.0 5.0 4 1 0 5 5 5 3 AAA domain SMC_N PF02463.14 ETO08909.1 - 1.8e-07 30.6 0.0 0.053 12.7 0.0 3.1 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 ETO08909.1 - 1.1e-05 25.2 0.0 0.056 13.3 0.0 3.4 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 ETO08909.1 - 0.0011 18.4 1.4 1.7 8.2 0.0 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain SRP54 PF00448.17 ETO08909.1 - 0.0033 16.9 3.5 0.57 9.6 0.1 2.5 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_23 PF13476.1 ETO08909.1 - 0.0046 17.3 17.6 0.099 12.9 0.0 4.0 4 0 0 4 4 4 2 AAA domain DUF258 PF03193.11 ETO08909.1 - 0.023 13.9 1.0 0.37 9.9 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function, DUF258 FLO_LFY PF01698.11 ETO08909.1 - 0.077 11.8 4.1 0.17 10.6 2.8 1.5 1 0 0 1 1 1 0 Floricaula / Leafy protein AAA_17 PF13207.1 ETO08909.1 - 0.079 13.7 0.3 1.4 9.7 0.0 3.0 2 0 0 2 2 2 0 AAA domain DUF4636 PF15468.1 ETO08909.1 - 0.12 11.8 5.0 0.45 9.9 3.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) DUF3301 PF11743.3 ETO08910.1 - 0.023 14.2 0.3 0.079 12.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) DUF4254 PF14063.1 ETO08910.1 - 1.4 8.4 12.0 0.77 9.3 0.2 3.7 3 1 0 4 4 4 0 Protein of unknown function (DUF4254) WD40 PF00400.27 ETO08911.1 - 2.3e-63 207.9 33.7 8.3e-13 47.6 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO08911.1 - 1e-09 37.1 2.0 0.00024 19.3 0.1 4.0 2 1 1 3 3 3 3 Nucleoporin Nup120/160 HAD PF12710.2 ETO08911.1 - 0.0083 16.3 1.2 0.27 11.3 0.0 2.7 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase DUF851 PF05867.6 ETO08911.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF851) Borrelia_orfD PF02999.9 ETO08912.1 - 0.2 11.8 1.6 6.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Borrelia orf-D family NPH3 PF03000.9 ETO08913.1 - 0.044 13.2 0.1 0.055 12.9 0.1 1.1 1 0 0 1 1 1 0 NPH3 family DUF413 PF04219.7 ETO08913.1 - 0.13 12.0 0.7 0.25 11.0 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF zf-CCHC PF00098.18 ETO08915.1 - 0.0013 18.5 1.7 0.0013 18.5 1.2 2.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.1 ETO08915.1 - 0.18 11.3 11.5 0.99 8.9 1.8 2.5 2 0 0 2 2 2 0 Zinc knuckle PSP94 PF05825.6 ETO08915.1 - 0.99 9.7 13.9 3.1 8.1 0.4 2.2 1 1 1 2 2 2 0 Beta-microseminoprotein (PSP-94) Nucleoporin2 PF04096.9 ETO08916.1 - 0.031 14.0 0.3 0.075 12.8 0.1 1.7 1 1 1 2 2 2 0 Nucleoporin autopeptidase Piwi PF02171.12 ETO08916.1 - 0.075 11.9 0.2 0.24 10.3 0.1 1.9 1 1 0 1 1 1 0 Piwi domain Tubulin_C PF03953.12 ETO08919.1 - 6.2e-36 123.2 0.0 7.3e-36 122.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin C-terminal domain DUF2762 PF10960.3 ETO08920.1 - 0.022 14.4 0.1 0.066 12.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) RepA_C PF04796.7 ETO08920.1 - 0.12 12.0 0.8 8.9 5.8 0.0 2.4 2 0 0 2 2 2 0 Plasmid encoded RepA protein Kelch_6 PF13964.1 ETO08920.1 - 0.15 12.3 0.4 1.7 8.9 0.0 2.7 3 0 0 3 3 3 0 Kelch motif Armet PF10208.4 ETO08921.1 - 0.0019 17.8 3.3 0.0041 16.7 2.3 1.5 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding PIG-Y PF15159.1 ETO08921.1 - 0.045 13.9 0.1 0.098 12.8 0.1 1.5 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF3782 PF12644.2 ETO08921.1 - 0.077 12.7 1.3 8.9 6.1 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3782) DrsE PF02635.10 ETO08921.1 - 0.16 12.0 0.7 0.29 11.1 0.5 1.6 1 1 0 1 1 1 0 DsrE/DsrF-like family Fib_alpha PF08702.5 ETO08921.1 - 0.66 10.0 13.1 0.068 13.2 6.1 1.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Tubulin PF00091.20 ETO08922.1 - 6.4e-44 150.3 0.0 8.1e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO08922.1 - 5.9e-07 29.5 0.1 1.4e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Tubulin C-terminal domain Lipase_3 PF01764.20 ETO08922.1 - 0.0017 17.9 0.0 0.0055 16.3 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) Misat_Tub_SegII PF10644.4 ETO08922.1 - 0.06 13.3 0.1 0.13 12.3 0.0 1.6 2 0 0 2 2 2 0 Misato Segment II tubulin-like domain SPATA24 PF15175.1 ETO08924.1 - 0.023 14.4 3.1 1.7 8.3 0.1 2.1 2 0 0 2 2 2 0 Spermatogenesis-associated protein 24 DUF1829 PF08862.5 ETO08924.1 - 0.12 12.6 3.6 0.13 12.5 1.9 1.6 1 1 0 1 1 1 0 Domain of unknown function DUF1829 NESP55 PF06390.7 ETO08924.1 - 0.74 9.1 3.2 0.88 8.8 2.2 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Mob1_phocein PF03637.12 ETO08927.1 - 1.5e-25 89.8 1.8 2.6e-25 89.0 1.3 1.4 1 0 0 1 1 1 1 Mob1/phocein family CLASP_N PF12348.3 ETO08927.1 - 0.079 12.3 0.5 0.13 11.6 0.3 1.5 1 1 0 1 1 1 0 CLASP N terminal Kelch_5 PF13854.1 ETO08928.1 - 2.1e-05 24.3 2.3 2.4 8.2 0.0 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 ETO08928.1 - 0.0004 20.4 2.9 9.1 6.6 0.0 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO08928.1 - 0.0031 17.2 3.5 21 5.0 0.0 5.1 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.1 ETO08928.1 - 0.0037 16.9 3.3 0.26 11.0 0.1 3.6 3 1 1 4 4 4 1 Galactose oxidase, central domain GF_recep_IV PF14843.1 ETO08928.1 - 0.23 11.0 2.3 0.51 9.9 1.6 1.5 1 0 0 1 1 1 0 Growth factor receptor domain IV DUF4523 PF15023.1 ETO08929.1 - 0.087 12.3 2.2 0.12 11.8 1.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4523) SR-25 PF10500.4 ETO08932.1 - 0.011 15.2 27.3 0.015 14.7 18.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MIP-T3 PF10243.4 ETO08932.1 - 0.66 8.3 29.3 0.81 8.0 20.3 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF853 PF05872.7 ETO08932.1 - 2.6 6.3 7.7 3.2 5.9 5.4 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) NOA36 PF06524.7 ETO08932.1 - 8.1 5.5 17.1 10 5.2 11.8 1.2 1 0 0 1 1 1 0 NOA36 protein PI3_PI4_kinase PF00454.22 ETO08933.1 - 1.3e-20 73.9 0.0 2e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.1 ETO08933.1 - 0.11 11.5 0.0 0.31 10.0 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4135) FKBP_C PF00254.23 ETO08934.1 - 1.1e-12 47.8 0.0 1.6e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.13 ETO08934.1 - 6.2e-07 29.4 0.0 1.2e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase GFO_IDH_MocA PF01408.17 ETO08936.1 - 2.3e-19 70.0 0.1 7.1e-19 68.4 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 ETO08936.1 - 4.8e-07 29.5 0.1 1.5e-06 27.9 0.0 1.8 1 1 1 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 ETO08936.1 - 1.9e-05 25.0 0.2 4.4e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain F420_oxidored PF03807.12 ETO08936.1 - 3.3e-05 24.2 0.0 6.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 ETO08936.1 - 0.0015 18.5 0.0 0.0025 17.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 ETO08936.1 - 0.0018 18.5 0.0 0.0029 17.8 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain PDDEXK_1 PF12705.2 ETO08937.1 - 0.1 11.9 0.3 0.12 11.7 0.2 1.2 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Ribosomal_S20p PF01649.13 ETO08937.1 - 7.8 6.9 9.8 6.3 7.2 5.7 1.6 2 0 0 2 2 2 0 Ribosomal protein S20 RecX PF02631.11 ETO08939.1 - 0.008 16.3 1.6 0.0093 16.1 1.1 1.2 1 0 0 1 1 1 1 RecX family DUF3139 PF11337.3 ETO08939.1 - 0.013 15.7 1.3 0.013 15.7 0.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3139) Pex14_N PF04695.8 ETO08939.1 - 0.025 14.6 1.6 0.036 14.1 0.4 1.7 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2229 PF09989.4 ETO08939.1 - 0.26 10.6 3.0 0.32 10.4 2.0 1.1 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) zf-C2H2 PF00096.21 ETO08940.1 - 1.3e-05 25.2 22.6 0.00012 22.2 1.3 4.0 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETO08940.1 - 0.00013 22.0 16.4 0.0059 16.8 1.3 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 ETO08940.1 - 0.18 11.9 17.6 0.17 12.0 3.8 2.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met2 PF12907.2 ETO08940.1 - 0.72 9.8 8.3 0.64 10.0 0.2 2.8 2 0 0 2 2 2 0 Zinc-binding zf-C2H2_jaz PF12171.3 ETO08940.1 - 1.7 8.8 8.2 0.6 10.3 0.4 3.6 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 ETO08940.1 - 9.5 6.6 13.5 3.9 7.9 0.2 4.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain LigB PF02900.13 ETO08942.1 - 8.2e-08 31.5 0.0 1e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase tRNA_m1G_MT PF01746.16 ETO08942.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 tRNA (Guanine-1)-methyltransferase Kelch_6 PF13964.1 ETO08943.1 - 0.0013 18.8 0.3 0.0066 16.5 0.0 2.1 2 1 0 2 2 2 1 Kelch motif Kelch_4 PF13418.1 ETO08943.1 - 0.011 15.4 0.0 0.061 13.1 0.0 2.1 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO08943.1 - 0.14 12.3 0.3 0.55 10.4 0.0 2.0 2 1 0 2 2 2 0 Galactose oxidase, central domain UPF1_Zn_bind PF09416.5 ETO08944.1 - 2.8e-11 43.2 5.7 2.8e-11 43.2 3.9 1.7 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) Kelch_6 PF13964.1 ETO08945.1 - 2.9e-07 30.3 2.7 0.075 13.2 0.0 4.6 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.1 ETO08945.1 - 9.1e-07 28.5 0.4 0.0028 17.4 0.0 4.3 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO08945.1 - 0.00021 20.7 1.3 0.052 13.0 0.0 3.7 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 ETO08945.1 - 0.00038 20.5 0.0 0.00038 20.5 0.0 4.5 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO08945.1 - 0.0031 17.1 7.4 0.012 15.3 0.1 4.3 4 1 0 4 4 4 1 Kelch motif Dicty_REP PF05086.7 ETO08945.1 - 0.0075 14.1 0.4 0.0096 13.7 0.3 1.2 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein PQQ_3 PF13570.1 ETO08945.1 - 0.079 13.2 0.1 11 6.5 0.0 2.9 3 0 0 3 3 3 0 PQQ-like domain Vps35 PF03635.12 ETO08946.1 - 8.9e-187 622.6 23.1 1.4e-185 618.7 16.0 2.3 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 MOSC PF03473.12 ETO08947.1 - 4.9e-19 68.1 0.0 6e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 MOSC domain GRIP PF01465.15 ETO08948.1 - 1.5e-09 37.2 0.1 3.8e-09 35.9 0.1 1.8 1 0 0 1 1 1 1 GRIP domain SR-25 PF10500.4 ETO08948.1 - 0.0064 15.9 15.5 0.0064 15.9 10.7 5.5 6 1 0 7 7 7 1 Nuclear RNA-splicing-associated protein SDA1 PF05285.7 ETO08949.1 - 0.15 11.3 22.4 0.16 11.2 15.5 1.1 1 0 0 1 1 1 0 SDA1 Bystin PF05291.6 ETO08949.1 - 0.21 10.4 2.2 0.25 10.2 1.5 1.2 1 0 0 1 1 1 0 Bystin DUF966 PF06136.8 ETO08949.1 - 0.72 9.2 6.5 0.7 9.2 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF262 PF03235.9 ETO08949.1 - 0.9 9.4 9.6 1.1 9.1 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 DUF913 PF06025.7 ETO08949.1 - 0.93 8.1 6.8 1 8.0 4.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Pox_Ag35 PF03286.9 ETO08949.1 - 2 7.9 16.1 2.5 7.6 11.1 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Raftlin PF15250.1 ETO08949.1 - 2.3 6.6 8.5 2.5 6.5 5.9 1.1 1 0 0 1 1 1 0 Raftlin Fmp27 PF10344.4 ETO08949.1 - 3.3 5.2 9.7 3.3 5.2 6.7 1.2 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 Vfa1 PF08432.5 ETO08949.1 - 3.5 7.6 16.2 4.2 7.3 11.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4045 PF13254.1 ETO08949.1 - 3.8 6.6 8.3 3.6 6.7 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Adeno_terminal PF02459.10 ETO08949.1 - 4.1 5.4 12.6 4.6 5.2 8.7 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Daxx PF03344.10 ETO08949.1 - 6.9 5.0 23.1 6.9 5.0 16.0 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 ETO08949.1 - 8.4 4.1 24.8 9.6 3.9 17.2 1.1 1 0 0 1 1 1 0 Nop14-like family Rota_VP2 PF05087.7 ETO08949.1 - 9.7 3.9 12.1 9.2 4.0 8.4 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein Abhydrolase_2 PF02230.11 ETO08950.1 - 2.5e-18 66.3 0.0 7e-16 58.3 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 ETO08950.1 - 1.8e-05 24.5 0.0 2.7e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETO08950.1 - 0.00032 19.9 0.0 0.00044 19.5 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 ETO08950.1 - 0.0082 15.4 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.8 ETO08950.1 - 0.027 13.9 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Neur_chan_memb PF02932.11 ETO08950.1 - 0.034 14.0 0.4 0.048 13.5 0.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region WBP-1 PF11669.3 ETO08950.1 - 0.045 13.8 0.1 0.083 12.9 0.1 1.4 1 0 0 1 1 1 0 WW domain-binding protein 1 Abhydrolase_6 PF12697.2 ETO08950.1 - 0.06 13.2 0.0 1.7 8.4 0.0 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 ETO08950.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 TAP-like protein Aldedh PF00171.17 ETO08951.1 - 2.2e-124 415.3 1.1 7e-109 364.2 0.3 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family AAA PF00004.24 ETO08952.1 - 6.9e-18 65.1 0.0 1.4e-17 64.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 ETO08952.1 - 0.032 14.1 0.0 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain Herpes_US9 PF06072.6 ETO08952.1 - 0.088 12.6 0.6 1.2 9.0 0.0 2.8 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 G-alpha PF00503.15 ETO08953.1 - 1.3e-62 211.7 5.0 8.9e-61 205.7 3.4 2.1 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO08953.1 - 5.1e-06 25.8 0.8 0.041 13.1 0.0 3.1 3 0 0 3 3 3 2 ADP-ribosylation factor family Arch_ATPase PF01637.13 ETO08953.1 - 0.012 15.3 0.7 0.025 14.2 0.5 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 ETO08953.1 - 0.029 14.2 1.2 0.22 11.4 0.4 2.9 3 1 0 3 3 3 0 AAA domain Ras PF00071.17 ETO08956.1 - 0.0077 15.6 0.6 0.66 9.3 0.0 2.4 1 1 1 2 2 2 2 Ras family TAFH PF07531.9 ETO08956.1 - 1.4 8.6 5.5 1.9 8.1 0.2 2.5 2 1 1 3 3 3 0 NHR1 homology to TAF RVT_1 PF00078.22 ETO08960.1 - 2.4e-17 62.9 0.0 4.5e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF871 PF05913.6 ETO08960.1 - 0.031 13.1 0.1 0.046 12.5 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF871) HSP90 PF00183.13 ETO08961.1 - 8.5e-97 324.7 46.7 3.1e-82 276.7 11.4 3.9 3 1 1 4 4 4 3 Hsp90 protein HATPase_c_3 PF13589.1 ETO08961.1 - 3.7e-08 33.0 1.5 1.1e-07 31.5 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 ETO08961.1 - 8.3e-06 25.5 0.0 1.7e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF778 PF05608.7 ETO08961.1 - 6.8 6.6 6.0 1.6 8.6 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF778) Atrophin-1 PF03154.10 ETO08963.1 - 0.0049 15.0 4.7 0.0069 14.6 3.3 1.1 1 0 0 1 1 1 1 Atrophin-1 family BAH PF01426.13 ETO08963.1 - 0.0058 16.3 1.8 0.21 11.3 0.0 2.8 3 0 0 3 3 3 1 BAH domain DUF2451 PF10474.4 ETO08963.1 - 0.0064 16.2 0.1 0.01 15.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Piwi PF02171.12 ETO08963.1 - 0.055 12.4 1.6 0.11 11.4 0.6 1.9 1 1 1 2 2 2 0 Piwi domain WD40 PF00400.27 ETO08964.1 - 4.1e-36 121.5 1.0 6e-15 54.4 0.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat eIF2A PF08662.6 ETO08964.1 - 0.00056 19.6 0.0 0.014 15.1 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Resistin PF06954.6 ETO08964.1 - 0.045 14.0 0.1 8.9 6.6 0.0 2.7 2 1 1 3 3 3 0 Resistin DUF4221 PF13970.1 ETO08964.1 - 0.077 12.2 0.1 0.34 10.1 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4221) PD40 PF07676.7 ETO08964.1 - 0.1 12.3 0.5 62 3.4 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Pkinase PF00069.20 ETO08965.1 - 1.6e-26 93.0 3.5 2.8e-17 62.7 1.8 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO08965.1 - 0.00038 19.6 0.1 0.068 12.2 0.1 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 ETO08965.1 - 0.0012 18.6 0.0 0.014 15.1 0.0 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family DUF3480 PF11979.3 ETO08965.1 - 0.01 14.4 1.0 0.035 12.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3480) IPPT PF01715.12 ETO08965.1 - 0.038 13.0 0.1 0.058 12.4 0.1 1.2 1 0 0 1 1 1 0 IPP transferase Exo_endo_phos_2 PF14529.1 ETO08966.1 - 1.5e-21 76.2 0.8 1.8e-21 75.9 0.5 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase WD40 PF00400.27 ETO08967.1 - 0.0019 18.0 0.2 0.004 16.9 0.2 1.6 1 0 0 1 1 1 1 WD domain, G-beta repeat Helicase_C_2 PF13307.1 ETO08968.1 - 0.032 14.1 0.0 0.035 14.0 0.0 1.1 1 0 0 1 1 1 0 Helicase C-terminal domain PPR PF01535.15 ETO08968.1 - 0.04 13.8 0.2 0.1 12.6 0.1 1.7 1 0 0 1 1 1 0 PPR repeat PPR_1 PF12854.2 ETO08968.1 - 0.055 12.9 0.1 0.098 12.1 0.1 1.5 1 0 0 1 1 1 0 PPR repeat Apc3 PF12895.2 ETO08968.1 - 0.25 11.5 4.2 0.37 10.9 2.9 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 WD40 PF00400.27 ETO08969.1 - 5e-15 54.7 4.5 2.1e-10 40.0 0.7 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO08969.1 - 0.0032 15.6 0.1 0.004 15.3 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO08969.1 - 0.005 16.1 1.6 0.0056 16.0 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4221) ArfGap PF01412.13 ETO08971.1 - 2.7e-38 130.3 1.6 2.7e-38 130.3 1.1 2.8 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf DUF3987 PF13148.1 ETO08971.1 - 2 6.8 9.4 3.3 6.1 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Zip PF02535.17 ETO08971.1 - 6.5 5.6 5.9 12 4.7 4.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Glyco_transf_92 PF01697.22 ETO08972.1 - 1.1e-10 41.3 11.2 1.1e-10 41.3 7.8 2.8 2 1 0 2 2 2 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.1 ETO08972.1 - 3.6e-06 27.1 1.2 5.5e-05 23.4 0.3 3.0 2 1 0 2 2 2 1 Glycosyl transferase family 2 PBP1_TM PF14812.1 ETO08973.1 - 0.0045 17.2 6.5 0.0045 17.2 4.5 2.3 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Myc_N PF01056.13 ETO08973.1 - 0.012 14.7 3.2 0.018 14.2 2.2 1.3 1 0 0 1 1 1 0 Myc amino-terminal region EBV-NA3 PF05009.7 ETO08973.1 - 0.031 13.5 1.0 0.047 12.9 0.7 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) SPOUT_MTase PF02590.12 ETO08973.1 - 0.031 13.9 0.5 0.031 13.9 0.4 1.8 2 0 0 2 2 2 0 Predicted SPOUT methyltransferase RNA_replicase_B PF03431.8 ETO08973.1 - 0.035 12.3 0.5 0.045 11.9 0.4 1.1 1 0 0 1 1 1 0 RNA replicase, beta-chain Zip PF02535.17 ETO08973.1 - 0.039 12.9 0.6 0.044 12.7 0.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RXT2_N PF08595.6 ETO08973.1 - 0.69 9.7 15.3 0.084 12.6 6.8 1.9 1 1 1 2 2 2 0 RXT2-like, N-terminal RR_TM4-6 PF06459.7 ETO08973.1 - 5.1 6.9 14.5 7.2 6.4 10.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDRGK PF09756.4 ETO08973.1 - 7.5 5.9 26.8 0.83 9.0 10.3 2.1 2 0 0 2 2 2 0 DDRGK domain FLO_LFY PF01698.11 ETO08973.1 - 10 4.8 18.0 13 4.5 12.5 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein RRM_1 PF00076.17 ETO08974.1 - 5.6e-05 22.6 0.0 0.00012 21.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO08974.1 - 0.00064 19.6 0.0 0.0017 18.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pro-rich PF15240.1 ETO08975.1 - 0.06 13.4 6.3 0.068 13.2 4.3 1.1 1 0 0 1 1 1 0 Proline-rich DUF1510 PF07423.6 ETO08975.1 - 0.44 9.8 27.8 0.5 9.7 19.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 ETO08975.1 - 0.47 8.4 18.8 0.54 8.2 13.0 1.0 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.10 ETO08975.1 - 0.6 8.6 18.9 0.7 8.4 13.1 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CobT PF06213.7 ETO08975.1 - 0.85 8.6 22.5 1.1 8.2 15.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FLO_LFY PF01698.11 ETO08975.1 - 1.4 7.6 13.0 1.6 7.4 9.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein FAM60A PF15396.1 ETO08975.1 - 2 8.1 14.3 2.4 7.8 9.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF4614 PF15391.1 ETO08975.1 - 2.3 7.9 13.7 2.9 7.6 9.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF3807 PF12720.2 ETO08975.1 - 2.6 8.1 19.0 3.4 7.7 13.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Nop14 PF04147.7 ETO08975.1 - 3 5.6 24.9 3.3 5.4 17.2 1.0 1 0 0 1 1 1 0 Nop14-like family Dsh_C PF12316.3 ETO08975.1 - 3.6 7.6 9.2 4.5 7.3 6.4 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF2457 PF10446.4 ETO08975.1 - 4.2 5.9 18.4 4.3 5.9 12.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Raftlin PF15250.1 ETO08975.1 - 7.3 4.9 16.3 8.4 4.7 11.3 1.1 1 0 0 1 1 1 0 Raftlin XAP5 PF04921.9 ETO08975.1 - 8 5.9 20.8 10 5.6 14.4 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator SID-1_RNA_chan PF13965.1 ETO08975.1 - 8.7 4.3 11.5 10 4.1 8.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Band_3_cyto PF07565.8 ETO08975.1 - 8.7 5.7 9.1 9.8 5.6 6.3 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Paramyxo_ncap PF00973.14 ETO08975.1 - 8.7 4.9 14.2 9.6 4.7 9.8 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Actin PF00022.14 ETO08976.1 - 3.5e-62 210.0 0.0 4e-62 209.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 ETO08976.1 - 0.044 12.3 0.0 0.045 12.3 0.0 1.3 1 1 0 1 1 1 0 MreB/Mbl protein DUF3586 PF12131.3 ETO08977.1 - 0.3 11.1 9.1 0.85 9.7 0.5 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3586) WD40 PF00400.27 ETO08978.1 - 4.3e-19 67.6 6.5 6.7e-11 41.6 0.1 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO08978.1 - 4.6e-07 28.3 1.3 0.00054 18.2 0.1 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO08978.1 - 0.00031 19.6 1.6 0.036 12.8 0.3 2.0 1 1 1 2 2 2 2 Nup133 N terminal like BBS2_N PF14781.1 ETO08978.1 - 0.0084 15.7 0.3 0.014 15.0 0.2 1.4 1 1 1 2 2 2 1 Ciliary BBSome complex subunit 2, N-terminal Peptidase_S9_N PF02897.10 ETO08978.1 - 0.0095 14.5 0.4 0.012 14.2 0.2 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain USP7_C2 PF14533.1 ETO08978.1 - 0.027 13.9 0.7 0.13 11.6 0.5 1.8 1 1 0 1 1 1 0 Ubiquitin-specific protease C-terminal DUF4221 PF13970.1 ETO08978.1 - 0.073 12.3 4.5 0.26 10.5 2.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4221) Ricin_B_lectin PF00652.17 ETO08978.1 - 0.22 11.5 6.0 0.28 11.2 4.2 1.1 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain DUF2559 PF10832.3 ETO08978.1 - 0.26 11.1 2.8 3 7.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2559) C2 PF00168.25 ETO08979.1 - 4.2e-07 29.7 1.1 1.5e-06 27.9 0.1 2.2 2 0 0 2 2 2 1 C2 domain Kelch_1 PF01344.20 ETO08980.1 - 5.5e-15 54.6 1.7 6.2e-05 22.4 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 ETO08980.1 - 1e-13 50.7 5.6 0.00016 21.7 0.0 5.3 3 2 2 5 5 5 3 Kelch motif Kelch_5 PF13854.1 ETO08980.1 - 9.1e-10 38.2 2.8 0.00011 22.0 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.1 ETO08980.1 - 1.6e-09 37.6 0.3 0.00044 20.3 0.0 4.9 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO08980.1 - 7.1e-07 28.9 1.0 0.34 10.7 0.0 4.8 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO08980.1 - 8e-07 28.5 1.4 1.8 8.4 0.0 5.3 5 0 0 5 5 5 2 Kelch motif OATP PF03137.15 ETO08981.1 - 0.00033 18.8 0.7 0.00053 18.1 0.5 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family TMEM154 PF15102.1 ETO08981.1 - 0.00046 19.9 0.6 0.001 18.7 0.4 1.6 1 0 0 1 1 1 1 TMEM154 protein family DcuC PF03606.10 ETO08981.1 - 0.0016 16.7 2.6 0.0023 16.2 1.8 1.1 1 0 0 1 1 1 1 C4-dicarboxylate anaerobic carrier Rifin_STEVOR PF02009.11 ETO08981.1 - 0.0019 17.8 0.1 0.0019 17.8 0.1 1.9 2 0 0 2 2 2 1 Rifin/stevor family MFS_1 PF07690.11 ETO08981.1 - 0.0036 16.0 0.0 0.0053 15.5 0.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily OSTbeta PF15048.1 ETO08981.1 - 0.0041 17.1 0.5 0.42 10.6 0.2 2.3 2 0 0 2 2 2 1 Organic solute transporter subunit beta protein TMEM51 PF15345.1 ETO08981.1 - 0.011 15.4 0.9 0.014 15.0 0.2 1.5 2 0 0 2 2 2 0 Transmembrane protein 51 UPF0104 PF03706.8 ETO08981.1 - 0.015 14.5 0.0 0.026 13.7 0.0 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0104) Ctr PF04145.10 ETO08981.1 - 0.019 15.0 1.9 0.036 14.1 1.3 1.4 1 0 0 1 1 1 0 Ctr copper transporter family EphA2_TM PF14575.1 ETO08981.1 - 0.026 14.9 0.9 0.087 13.2 0.6 2.0 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SCIMP PF15050.1 ETO08981.1 - 0.043 13.7 0.1 0.088 12.7 0.1 1.5 1 0 0 1 1 1 0 SCIMP protein DUF912 PF06024.7 ETO08981.1 - 0.057 13.4 10.1 0.2 11.7 0.3 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FAM176 PF14851.1 ETO08981.1 - 0.076 12.6 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 FAM176 family DUF2615 PF11027.3 ETO08981.1 - 0.14 12.1 0.9 0.38 10.6 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) DUF3377 PF11857.3 ETO08981.1 - 0.18 11.4 2.3 0.15 11.6 0.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3377) CD34_antigen PF06365.7 ETO08981.1 - 0.37 10.4 3.6 0.2 11.2 0.3 2.1 2 1 1 3 3 3 0 CD34/Podocalyxin family Tsg PF04668.7 ETO08981.1 - 0.45 10.7 8.5 0.15 12.2 2.7 2.3 2 1 0 2 2 2 0 Twisted gastrulation (Tsg) protein conserved region DUF3753 PF12575.3 ETO08981.1 - 0.51 10.1 6.0 0.89 9.3 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) G-alpha PF00503.15 ETO08982.1 - 6.2e-27 94.2 1.5 7.6e-27 93.9 1.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO08982.1 - 0.028 13.6 0.1 0.045 12.9 0.1 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family ABC_tran PF00005.22 ETO08982.1 - 0.029 14.6 0.2 0.083 13.1 0.1 1.8 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 ETO08982.1 - 0.034 13.6 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Molybdopterin PF00384.17 ETO08983.1 - 1.2e-53 182.4 0.0 4.1e-28 98.3 0.0 2.1 1 1 1 2 2 2 2 Molybdopterin oxidoreductase WD40 PF00400.27 ETO08985.1 - 4.9e-37 124.4 12.2 6.5e-10 38.5 0.0 4.7 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO08985.1 - 3.7e-09 35.2 1.3 0.0093 14.1 0.0 3.2 1 1 2 3 3 3 3 Nucleoporin Nup120/160 YqzH PF14164.1 ETO08985.1 - 0.041 13.8 1.3 0.12 12.3 0.7 2.0 1 1 0 1 1 1 0 YqzH-like protein ORC5_C PF14630.1 ETO08986.1 - 0.12 11.8 0.6 0.14 11.6 0.4 1.1 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus WD40 PF00400.27 ETO08987.1 - 8.8e-18 63.4 3.9 7.2e-11 41.5 0.9 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO08987.1 - 0.028 12.5 1.2 0.69 7.9 0.1 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 DUF1030 PF06270.6 ETO08987.1 - 0.062 12.8 4.2 0.091 12.3 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1030) YfdX PF10938.3 ETO08989.1 - 0.011 15.3 3.3 1.7 8.3 0.3 2.3 2 0 0 2 2 2 0 YfdX protein WD40 PF00400.27 ETO08991.1 - 0.0049 16.6 0.2 0.012 15.5 0.0 1.9 2 0 0 2 2 2 1 WD domain, G-beta repeat HAP1_N PF04849.8 ETO08992.1 - 0.00015 20.7 2.0 0.00017 20.6 1.4 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Rootletin PF15035.1 ETO08992.1 - 0.013 15.5 5.1 0.02 14.8 3.6 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Atg14 PF10186.4 ETO08992.1 - 0.02 13.8 3.4 0.032 13.1 2.4 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Spc24 PF08286.6 ETO08992.1 - 0.055 13.1 7.8 0.11 12.2 5.4 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 SlyX PF04102.7 ETO08992.1 - 0.27 11.6 2.7 0.63 10.4 1.9 1.6 1 0 0 1 1 1 0 SlyX DUF1542 PF07564.6 ETO08992.1 - 3.4 7.7 10.5 7 6.7 4.0 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) DUF2339 PF10101.4 ETO08993.1 - 0.015 13.6 0.3 0.015 13.6 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) DUF1192 PF06698.6 ETO08995.1 - 0.063 13.0 3.6 2 8.2 0.8 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF3924 PF13062.1 ETO08995.1 - 4.4 7.2 7.7 7.6 6.4 0.3 3.7 4 1 0 4 4 4 0 Protein of unknown function (DUF3924) TORC_M PF12885.2 ETO08996.1 - 0.044 13.5 12.7 0.11 12.2 8.8 1.6 1 1 0 1 1 1 0 Transducer of regulated CREB activity middle domain CDC45 PF02724.9 ETO08996.1 - 0.4 8.6 19.5 0.46 8.4 13.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 ETO08996.1 - 0.53 8.7 23.9 0.61 8.4 16.6 1.0 1 0 0 1 1 1 0 Daxx Family FLO_LFY PF01698.11 ETO08996.1 - 0.87 8.3 17.9 1 8.1 12.4 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein SprA-related PF12118.3 ETO08996.1 - 1.2 8.3 23.1 1.4 8.1 16.0 1.0 1 0 0 1 1 1 0 SprA-related family MIP-T3 PF10243.4 ETO08996.1 - 2.5 6.4 25.4 3.1 6.1 17.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Raftlin PF15250.1 ETO08996.1 - 4.4 5.7 13.1 5.3 5.4 9.0 1.2 1 0 0 1 1 1 0 Raftlin Ycf1 PF05758.7 ETO08996.1 - 5.4 4.5 14.5 6.2 4.4 10.1 1.0 1 0 0 1 1 1 0 Ycf1 BTV_NS2 PF04514.7 ETO08996.1 - 8.6 5.1 17.1 9.6 4.9 11.9 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 zf-C2H2_4 PF13894.1 ETO08997.1 - 6.4e-10 38.6 30.9 0.00058 20.0 1.1 6.2 6 1 0 6 6 6 4 C2H2-type zinc finger zf-C2H2 PF00096.21 ETO08997.1 - 5.6e-06 26.3 44.3 0.0024 18.0 1.0 6.6 6 1 1 7 7 7 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETO08997.1 - 2.2e-05 24.5 1.8 2.2e-05 24.5 1.2 6.2 7 1 0 7 7 7 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 ETO08997.1 - 0.00015 21.7 26.4 0.0041 17.2 0.6 6.0 7 0 0 7 7 7 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 ETO08997.1 - 0.044 13.7 28.5 0.61 10.0 1.1 6.2 6 0 0 6 6 6 0 C2H2-type zinc finger zf-CHCC PF10276.4 ETO08997.1 - 0.099 12.5 6.0 0.18 11.6 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger domain zf-met PF12874.2 ETO08997.1 - 0.1 12.8 0.2 0.1 12.8 0.1 6.7 7 0 0 7 7 7 0 Zinc-finger of C2H2 type zf-BED PF02892.10 ETO08997.1 - 0.27 11.0 26.1 0.093 12.5 2.0 4.2 2 2 1 3 3 2 0 BED zinc finger zf-FCS PF06467.9 ETO08997.1 - 0.61 9.7 20.5 4 7.1 0.1 5.2 5 2 0 5 5 5 0 MYM-type Zinc finger with FCS sequence motif zf-H2C2_5 PF13909.1 ETO08997.1 - 2 8.8 18.2 0.082 13.1 1.4 4.6 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-RING_3 PF14369.1 ETO08997.1 - 3 7.9 11.8 17 5.5 0.1 4.3 4 0 0 4 4 4 0 zinc-finger DAO PF01266.19 ETO08998.1 - 4.8e-27 94.7 0.0 9.4e-27 93.8 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase ThiF PF00899.16 ETO08998.1 - 0.0066 16.2 0.7 0.37 10.6 0.0 3.1 3 0 0 3 3 3 1 ThiF family Thi4 PF01946.12 ETO08998.1 - 0.029 13.4 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 ETO08998.1 - 0.1 12.6 0.6 13 5.7 0.0 2.9 2 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF4366 PF14283.1 ETO08998.1 - 0.21 10.9 6.3 1.9 7.8 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) EMP70 PF02990.11 ETO08998.1 - 4.1 5.7 8.9 1.2 7.5 1.7 2.7 3 0 0 3 3 3 0 Endomembrane protein 70 PIP5K PF01504.13 ETO08999.1 - 1.9e-26 92.7 0.1 2.6e-26 92.2 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase PIP5K PF01504.13 ETO09000.1 - 2.6e-11 43.0 0.5 6.3e-09 35.3 0.0 2.2 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Pkinase PF00069.20 ETO09001.1 - 4.7e-44 150.4 0.0 8.3e-44 149.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO09001.1 - 6.5e-30 104.0 0.0 8e-30 103.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO09001.1 - 9.4e-06 24.7 0.0 1.7e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 ETO09001.1 - 0.0037 16.1 0.0 0.0069 15.2 0.0 1.3 1 1 0 1 1 1 1 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 ETO09001.1 - 0.013 14.3 0.0 0.036 12.8 0.0 1.7 2 0 0 2 2 2 0 Seadornavirus VP7 APH PF01636.18 ETO09001.1 - 0.016 14.9 0.0 0.036 13.7 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Maelstrom PF13017.1 ETO09001.1 - 0.028 13.8 0.0 0.062 12.7 0.0 1.5 1 0 0 1 1 1 0 piRNA pathway germ-plasm component DUF4635 PF15466.1 ETO09002.1 - 0.077 12.2 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) Gal4_dimer PF03902.8 ETO09003.1 - 0.058 13.3 0.2 0.17 11.8 0.1 1.8 1 0 0 1 1 1 0 Gal4-like dimerisation domain Otopetrin PF03189.8 ETO09003.1 - 0.22 10.4 2.5 0.29 10.0 1.7 1.1 1 0 0 1 1 1 0 Otopetrin WD40 PF00400.27 ETO09004.1 - 5.9e-12 44.9 0.4 5.9e-12 44.9 0.3 3.1 3 1 0 3 3 3 2 WD domain, G-beta repeat CytochromB561_N PF09786.4 ETO09005.1 - 0.04 12.3 3.2 0.053 11.9 2.2 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal WD40 PF00400.27 ETO09007.1 - 4.6e-16 58.0 7.5 2.7e-11 42.8 1.8 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO09007.1 - 8.6e-05 20.8 0.2 0.00013 20.2 0.1 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 TraP PF07296.6 ETO09007.1 - 0.08 11.8 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 TraP protein RhoGAP PF00620.22 ETO09008.1 - 1.1e-30 106.2 0.2 2.7e-30 104.9 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain NACHT PF05729.7 ETO09010.1 - 6.5e-08 32.4 0.0 1.6e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 ETO09010.1 - 1.1e-06 27.7 0.4 2.9e-06 26.3 0.3 1.7 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 ETO09010.1 - 4.7e-05 23.5 0.0 0.00018 21.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETO09010.1 - 0.00049 20.3 0.1 0.00049 20.3 0.1 3.1 3 1 0 3 3 3 1 AAA domain RelA_SpoT PF04607.12 ETO09010.1 - 0.0017 18.3 0.4 0.0082 16.1 0.3 2.2 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins AAA_17 PF13207.1 ETO09010.1 - 0.0045 17.8 0.9 0.017 15.8 0.0 2.6 3 0 0 3 3 3 1 AAA domain HTH_Tnp_Mu_1 PF02316.11 ETO09010.1 - 0.099 12.3 0.1 0.67 9.6 0.0 2.3 2 0 0 2 2 2 0 Mu DNA-binding domain WD40 PF00400.27 ETO09011.1 - 3.3e-88 286.7 16.6 3.4e-12 45.7 0.1 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 ETO09011.1 - 1.2e-09 36.8 13.8 0.15 10.1 0.0 7.5 1 1 5 7 7 7 5 Nucleoporin Nup120/160 Pentapeptide_4 PF13599.1 ETO09011.1 - 6.7e-06 25.8 0.2 1.9e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETO09011.1 - 1.9e-05 23.7 0.3 3.9e-05 22.7 0.2 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) DUF727 PF05303.7 ETO09011.1 - 0.0006 19.5 0.5 6.4 6.6 0.0 5.1 3 3 3 6 6 6 1 Protein of unknown function (DUF727) DUF1258 PF06869.7 ETO09011.1 - 0.00061 18.9 0.2 0.037 13.1 0.1 3.6 2 1 1 3 3 3 1 Protein of unknown function (DUF1258) Pentapeptide_3 PF13576.1 ETO09011.1 - 0.00063 19.5 0.8 0.0015 18.3 0.1 2.0 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) Mid2 PF04478.7 ETO09011.1 - 0.00091 18.6 4.5 2.1 7.7 0.0 5.5 4 1 2 6 6 6 1 Mid2 like cell wall stress sensor Cytochrom_D1 PF02239.11 ETO09011.1 - 0.003 15.9 5.5 0.7 8.1 0.1 3.2 2 1 1 3 3 3 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO09011.1 - 0.017 14.5 0.8 1.5 8.2 0.0 2.5 1 1 0 2 2 2 0 PQQ-like domain Cas_Cmr5 PF09701.5 ETO09011.1 - 0.02 15.0 1.2 0.044 13.9 0.8 1.5 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr5) Nucleoporin_N PF08801.6 ETO09011.1 - 0.1 11.3 16.2 0.6 8.7 0.5 5.2 1 1 5 6 6 6 0 Nup133 N terminal like WD40 PF00400.27 ETO09012.1 - 3.9e-27 93.0 2.7 8.5e-11 41.3 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO09012.1 - 0.0081 14.3 0.0 0.068 11.3 0.0 2.3 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO09012.1 - 0.0081 14.9 5.6 0.88 8.2 1.3 3.3 1 1 1 2 2 2 2 Nup133 N terminal like Resistin PF06954.6 ETO09012.1 - 0.069 13.4 0.4 6.2 7.1 0.0 2.4 1 1 1 2 2 2 0 Resistin WD40 PF00400.27 ETO09015.1 - 5.9e-27 92.5 6.9 7e-10 38.4 0.1 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat PD40 PF07676.7 ETO09015.1 - 1.2e-06 28.0 3.6 0.58 9.8 0.1 3.5 3 0 0 3 3 3 3 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO09015.1 - 8.4e-05 21.4 0.3 0.12 11.1 0.0 2.3 2 0 0 2 2 2 2 Nup133 N terminal like Nup160 PF11715.3 ETO09015.1 - 0.00058 18.1 2.2 0.15 10.1 0.1 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 ETO09015.1 - 0.017 14.2 0.1 3.8 6.5 0.0 2.6 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal SGL PF08450.7 ETO09015.1 - 0.06 12.7 0.1 0.56 9.5 0.0 2.4 2 1 1 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 ETO09015.1 - 0.082 12.9 0.0 3.4 7.7 0.0 2.8 2 1 0 3 3 3 0 Strictosidine synthase Resistin PF06954.6 ETO09015.1 - 0.084 13.1 6.8 0.64 10.3 0.0 3.5 2 2 2 4 4 4 0 Resistin NACHT PF05729.7 ETO09016.1 - 2e-07 30.8 0.0 4.3e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO09016.1 - 0.00019 21.7 0.2 0.00095 19.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETO09016.1 - 0.00043 20.4 0.0 0.0039 17.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ETO09016.1 - 0.0017 19.1 0.1 0.017 15.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain RelA_SpoT PF04607.12 ETO09016.1 - 0.006 16.5 4.7 0.011 15.7 0.1 3.1 3 0 0 3 3 3 1 Region found in RelA / SpoT proteins AAA_16 PF13191.1 ETO09016.1 - 0.026 14.4 0.1 0.23 11.4 0.0 2.2 1 1 0 1 1 1 0 AAA ATPase domain ATP_bind_2 PF03668.10 ETO09016.1 - 0.036 13.1 0.1 0.11 11.5 0.0 1.8 2 0 0 2 2 2 0 P-loop ATPase protein family RNA_helicase PF00910.17 ETO09016.1 - 0.037 14.1 2.9 0.082 13.0 0.1 2.8 2 1 0 2 2 2 0 RNA helicase ABC_tran PF00005.22 ETO09016.1 - 0.081 13.2 0.1 0.58 10.4 0.0 2.5 3 0 0 3 3 3 0 ABC transporter BRCT PF00533.21 ETO09017.1 - 0.015 15.4 2.5 0.024 14.7 0.2 2.2 2 1 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Ta0938 PF11494.3 ETO09020.1 - 0.13 12.3 0.7 0.24 11.5 0.5 1.6 1 1 0 1 1 1 0 Ta0938 ABM PF03992.11 ETO09022.1 - 0.067 13.2 0.2 0.12 12.4 0.2 1.3 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase WD40 PF00400.27 ETO09023.1 - 4.2e-29 99.3 16.3 4.6e-08 32.6 0.1 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO09023.1 - 0.00042 18.5 3.1 1.3 7.0 0.1 3.6 3 1 0 3 3 3 3 Nucleoporin Nup120/160 Scm3 PF10384.4 ETO09024.1 - 0.00083 18.8 2.5 0.057 12.9 0.4 3.6 3 0 0 3 3 3 1 Centromere protein Scm3 GPW_gp25 PF04965.9 ETO09024.1 - 0.031 13.8 0.3 0.94 9.0 0.0 3.2 3 1 0 3 3 3 0 Gene 25-like lysozyme COG5 PF10392.4 ETO09024.1 - 0.041 13.8 5.7 0.26 11.2 0.2 3.7 2 1 2 4 4 4 0 Golgi transport complex subunit 5 DUF948 PF06103.6 ETO09024.1 - 0.38 10.6 12.8 1.8 8.4 0.7 4.2 4 1 2 6 6 6 0 Bacterial protein of unknown function (DUF948) DUF3158 PF11358.3 ETO09024.1 - 0.38 10.2 4.5 13 5.2 0.1 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF3158) Uds1 PF15456.1 ETO09024.1 - 0.99 9.4 11.8 0.79 9.7 2.7 3.1 3 0 0 3 3 3 0 Up-regulated During Septation Img2 PF05046.9 ETO09024.1 - 1 9.6 10.1 7.6 6.8 3.3 3.2 1 1 1 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) CompInhib_SCIN PF11546.3 ETO09024.1 - 3.2 7.6 11.7 11 5.9 0.8 4.0 3 1 1 5 5 5 0 Staphylococcal complement inhibitor SCIN Syntaxin-6_N PF09177.6 ETO09024.1 - 4.5 7.7 17.2 1 9.7 0.8 4.5 4 1 1 5 5 5 0 Syntaxin 6, N-terminal HSCB_C PF07743.8 ETO09024.1 - 6.8 7.2 19.6 19 5.8 0.2 5.5 4 1 2 6 6 6 0 HSCB C-terminal oligomerisation domain Atg14 PF10186.4 ETO09024.1 - 7.3 5.4 15.8 0.92 8.3 5.3 2.7 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Baculo_PEP_C PF04513.7 ETO09025.1 - 0.53 10.1 7.6 20 4.9 0.1 3.7 3 2 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus GrpE PF01025.14 ETO09025.1 - 1.6 8.2 22.5 0.091 12.2 7.1 3.4 3 0 0 3 3 3 0 GrpE Lebercilin PF15619.1 ETO09025.1 - 4 6.8 36.5 0.18 11.1 5.9 3.7 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Acyltransferase PF01553.16 ETO09027.1 - 0.028 13.8 0.0 0.049 13.0 0.0 1.5 1 0 0 1 1 1 0 Acyltransferase DUF1945 PF09178.5 ETO09027.1 - 0.068 13.0 1.5 0.85 9.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1945) Phage_min_tail PF05939.8 ETO09028.1 - 0.06 13.3 0.1 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Phage minor tail protein YqzH PF14164.1 ETO09028.1 - 0.21 11.5 4.2 0.22 11.4 0.2 2.7 2 1 1 3 3 3 0 YqzH-like protein Toxin_64 PF15542.1 ETO09028.1 - 1.4 9.4 4.8 1.3 9.6 1.6 2.0 1 1 1 2 2 2 0 Putative toxin 64 WD40 PF00400.27 ETO09029.1 - 3.3e-12 45.7 5.2 1.1e-10 40.9 0.2 3.2 3 1 0 3 3 3 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO09029.1 - 0.054 11.6 0.1 0.43 8.6 0.0 1.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 RNase_H PF00075.19 ETO09030.1 - 0.013 15.8 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 RNase H Cas_Csa4 PF09703.5 ETO09031.1 - 0.62 8.9 4.7 0.22 10.4 1.3 1.6 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csa4) PRD PF00874.15 ETO09031.1 - 1.1 9.3 6.9 0.71 10.0 1.8 2.5 2 1 0 2 2 2 0 PRD domain Translat_reg PF01818.12 ETO09032.1 - 0.082 12.4 0.1 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage translational regulator DUF1580 PF07618.6 ETO09033.1 - 0.0036 16.6 0.1 0.011 15.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1580) DUF87 PF01935.12 ETO09035.1 - 0.44 10.3 11.9 0.023 14.5 3.6 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 ATP-synt_B PF00430.13 ETO09035.1 - 4.9 6.9 15.6 0.11 12.3 5.6 2.2 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) DUF883 PF05957.8 ETO09035.1 - 5.5 7.4 5.9 1.8 9.0 1.5 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Pro_isomerase PF00160.16 ETO09036.1 - 1.8e-40 138.6 1.9 1.9e-40 138.6 0.0 2.1 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 ETO09036.1 - 7.4e-15 54.3 0.0 2.6e-14 52.6 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO09036.1 - 2.9e-10 39.9 0.0 8e-10 38.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO09036.1 - 3e-08 33.3 0.0 8.7e-08 31.8 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HEAT PF02985.17 ETO09038.1 - 0.033 14.2 0.1 5 7.4 0.0 3.4 2 0 0 2 2 2 0 HEAT repeat PBP1_TM PF14812.1 ETO09039.1 - 0.0024 18.1 11.3 0.0047 17.2 7.9 1.4 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DALR_1 PF05746.10 ETO09039.1 - 0.11 12.4 1.6 0.29 11.0 1.1 1.8 1 0 0 1 1 1 0 DALR anticodon binding domain Membr_traf_MHD PF10540.4 ETO09039.1 - 0.46 10.2 6.1 0.42 10.4 2.6 2.1 2 0 0 2 2 2 0 Munc13 (mammalian uncoordinated) homology domain RNA_pol_3_Rpc31 PF11705.3 ETO09039.1 - 1.6 8.6 11.9 2.8 7.8 8.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nucleoplasmin PF03066.10 ETO09039.1 - 4 6.9 10.0 6.9 6.1 6.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin WD40 PF00400.27 ETO09040.1 - 2.1e-47 157.3 17.9 4.1e-09 35.9 0.8 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO09040.1 - 1.7e-06 26.5 8.5 5.3e-05 21.5 0.7 4.1 1 1 3 4 4 4 2 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO09040.1 - 0.00022 21.5 0.7 0.0012 19.1 0.5 2.4 1 0 0 1 1 1 1 TRAF-type zinc finger Mem_trans PF03547.13 ETO09040.1 - 0.014 13.6 1.6 0.021 13.1 1.1 1.2 1 0 0 1 1 1 0 Membrane transport protein DUF3373 PF11853.3 ETO09040.1 - 0.018 13.6 4.6 0.026 13.0 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Flu_B_M2 PF04772.7 ETO09040.1 - 0.055 13.5 4.0 0.13 12.2 2.8 1.7 1 0 0 1 1 1 0 Influenza B matrix protein 2 (BM2) AP4E_app_platf PF14807.1 ETO09040.1 - 1.9 8.7 7.0 0.41 10.9 1.8 2.1 2 0 0 2 2 2 0 Adaptin AP4 complex epsilon appendage platform Peptidase_S49_N PF08496.5 ETO09040.1 - 1.9 8.2 8.0 3.9 7.2 5.5 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TPR_12 PF13424.1 ETO09041.1 - 9.6e-109 355.4 25.9 5.3e-26 90.3 0.2 4.5 1 1 5 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.1 ETO09041.1 - 2.6e-44 147.9 0.0 2.4e-09 36.8 0.0 6.2 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETO09041.1 - 8e-43 143.9 34.6 2.1e-15 56.0 2.3 4.5 2 1 3 5 5 5 5 TPR repeat TPR_7 PF13176.1 ETO09041.1 - 1.7e-38 127.3 3.4 9e-08 31.3 0.0 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.23 ETO09041.1 - 2.3e-34 115.5 37.1 1.6e-08 33.8 0.6 7.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETO09041.1 - 4.2e-31 104.3 22.8 6.1e-06 25.7 0.3 6.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 ETO09041.1 - 6.3e-23 78.7 46.1 8.2e-06 25.2 1.2 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETO09041.1 - 3.9e-22 76.5 4.6 0.00028 20.8 0.0 6.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO09041.1 - 1.9e-11 44.3 0.2 0.0016 19.0 0.0 4.4 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO09041.1 - 3.9e-10 39.4 0.0 0.84 10.4 0.0 5.5 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO09041.1 - 1.5e-08 34.5 7.0 0.0026 18.1 0.1 5.9 6 0 0 6 6 5 1 Tetratricopeptide repeat PPR PF01535.15 ETO09041.1 - 8.9e-08 31.6 17.7 0.15 12.0 0.0 7.3 8 0 0 8 8 8 3 PPR repeat Apc3 PF12895.2 ETO09041.1 - 1.2e-07 31.6 16.1 0.012 15.7 2.7 5.1 1 1 5 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO09041.1 - 2e-06 28.0 1.9 0.19 12.0 0.2 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_3 PF07720.7 ETO09041.1 - 0.0047 16.6 27.7 0.12 12.2 0.1 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO09041.1 - 0.0054 15.9 0.1 13 5.0 0.0 4.3 5 0 0 5 5 5 0 SHNi-TPR DUF627 PF04781.7 ETO09041.1 - 0.048 13.2 16.3 7.3 6.2 0.0 6.2 3 1 4 7 7 7 0 Protein of unknown function (DUF627) MIT PF04212.13 ETO09041.1 - 0.72 9.7 20.7 8.4 6.3 0.4 5.8 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.1 ETO09041.1 - 1.4 8.8 16.6 6.4 6.7 0.0 5.4 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Abhydrolase_5 PF12695.2 ETO09044.1 - 0.0024 17.6 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF818 PF05677.7 ETO09045.1 - 0.0015 17.3 0.0 0.0023 16.7 0.0 1.3 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_5 PF12695.2 ETO09045.1 - 0.0061 16.3 0.0 0.0099 15.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETO09045.1 - 0.15 11.8 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Herpes_LMP1 PF05297.6 ETO09045.1 - 6 5.6 5.9 7.9 5.2 4.1 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) NACHT PF05729.7 ETO09046.1 - 3.2e-07 30.1 0.0 6.7e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETO09046.1 - 0.00095 19.2 0.0 0.0025 17.8 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 ETO09046.1 - 0.0061 15.4 0.9 0.076 11.8 0.0 2.2 2 1 0 2 2 2 1 NB-ARC domain AAA_19 PF13245.1 ETO09046.1 - 0.037 13.7 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain Phe_hydrox_dim PF07976.7 ETO09046.1 - 0.045 13.3 2.6 0.35 10.4 0.1 2.4 1 1 2 3 3 3 0 Phenol hydroxylase, C-terminal dimerisation domain AAA_22 PF13401.1 ETO09046.1 - 0.061 13.4 0.7 0.36 10.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain SMC_N PF02463.14 ETO09046.1 - 0.22 10.7 0.0 0.22 10.7 0.0 2.6 2 1 1 3 3 3 0 RecF/RecN/SMC N terminal domain DUF2407 PF10302.4 ETO09046.1 - 0.67 10.1 8.3 2.1 8.5 5.8 1.8 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain SmpA_OmlA PF04355.8 ETO09050.1 - 0.0046 16.5 0.1 0.72 9.5 0.0 2.3 2 0 0 2 2 2 2 SmpA / OmlA family Myb_CC_LHEQLE PF14379.1 ETO09051.1 - 0.062 12.8 3.6 0.15 11.7 2.5 1.6 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif DivIC PF04977.10 ETO09051.1 - 0.44 10.0 16.4 0.21 11.0 3.2 2.4 2 0 0 2 2 2 0 Septum formation initiator ESSS PF10183.4 ETO09052.1 - 0.035 14.5 1.1 0.59 10.5 0.1 2.4 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF4446 PF14584.1 ETO09053.1 - 0.017 14.9 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) NinG PF05766.7 ETO09053.1 - 0.058 13.1 0.3 0.069 12.8 0.2 1.1 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein WD40 PF00400.27 ETO09054.1 - 8.8e-62 202.9 29.3 5.4e-12 45.1 0.3 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO09054.1 - 3e-11 42.1 5.2 0.22 9.6 0.0 5.7 1 1 4 5 5 5 5 Nucleoporin Nup120/160 WD40 PF00400.27 ETO09055.1 - 5.1e-66 216.3 31.5 1.8e-11 43.4 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO09055.1 - 6.2e-07 27.9 3.6 0.21 9.6 0.0 5.2 4 1 1 6 6 6 3 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO09055.1 - 6.6e-07 29.6 2.2 1.9e-06 28.1 0.7 2.5 1 1 1 2 2 2 1 TRAF-type zinc finger DUF621 PF04789.10 ETO09055.1 - 0.066 12.2 3.2 0.097 11.6 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF621) HALZ PF02183.13 ETO09055.1 - 0.36 10.5 8.8 0.32 10.7 1.9 3.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF3505 PF12013.3 ETO09055.1 - 5.9 7.1 10.2 0.44 10.8 0.5 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3505) Med15 PF09606.5 ETO09056.1 - 0.00048 18.4 23.4 0.00079 17.7 16.2 1.4 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Macoilin PF09726.4 ETO09056.1 - 0.00077 17.8 9.7 0.0014 17.0 6.8 1.4 1 0 0 1 1 1 1 Transmembrane protein Shisa PF13908.1 ETO09056.1 - 0.062 13.4 12.7 0.76 9.9 7.2 2.5 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Suf PF05843.9 ETO09056.1 - 0.14 11.8 17.3 0.23 11.1 12.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Rtf2 PF04641.7 ETO09056.1 - 0.19 10.9 13.8 0.33 10.1 9.6 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Gag_spuma PF03276.9 ETO09056.1 - 0.2 9.9 20.6 0.18 10.0 12.8 1.8 2 0 0 2 2 2 0 Spumavirus gag protein DUF4557 PF15101.1 ETO09056.1 - 0.23 11.3 15.6 0.51 10.1 10.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) FAM176 PF14851.1 ETO09056.1 - 0.27 10.9 5.5 0.54 9.9 3.8 1.6 1 0 0 1 1 1 0 FAM176 family F-protein PF00469.15 ETO09056.1 - 0.33 10.3 8.1 0.61 9.4 5.6 1.4 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef SR-25 PF10500.4 ETO09056.1 - 0.4 10.1 26.7 1.3 8.3 5.4 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.8 ETO09056.1 - 0.42 10.4 26.6 0.64 9.8 18.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mem_trans PF03547.13 ETO09056.1 - 0.46 8.7 13.1 1.5 6.9 9.1 1.8 1 1 0 1 1 1 0 Membrane transport protein LicD PF04991.8 ETO09056.1 - 0.57 10.2 8.2 1.2 9.2 5.7 1.5 1 0 0 1 1 1 0 LicD family Band_3_cyto PF07565.8 ETO09056.1 - 0.57 9.6 13.3 0.13 11.7 6.8 1.8 2 0 0 2 2 1 0 Band 3 cytoplasmic domain Zip PF02535.17 ETO09056.1 - 0.66 8.9 4.5 1.1 8.1 3.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2215 PF10225.4 ETO09056.1 - 1.1 8.6 11.6 2.9 7.2 8.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Serinc PF03348.10 ETO09056.1 - 1.2 7.7 17.9 0.3 9.7 9.9 1.7 2 0 0 2 2 2 0 Serine incorporator (Serinc) AIF_C PF14721.1 ETO09056.1 - 2.2 8.5 13.0 5.6 7.2 9.0 1.6 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Peptidase_S49_N PF08496.5 ETO09056.1 - 3.1 7.5 18.8 0.94 9.2 8.6 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF2946 PF11162.3 ETO09056.1 - 3.3 7.9 7.7 8.8 6.5 5.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) BAF1_ABF1 PF04684.8 ETO09056.1 - 3.3 6.4 23.8 6.3 5.5 16.5 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Gastrin PF00918.12 ETO09056.1 - 3.5 8.4 17.3 1.5 9.6 9.6 2.1 2 0 0 2 2 2 0 Gastrin/cholecystokinin family FLO_LFY PF01698.11 ETO09056.1 - 3.6 6.3 12.9 5.7 5.6 8.9 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF1980 PF09323.5 ETO09056.1 - 7.1 6.3 19.3 1.1 8.9 10.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) SprA-related PF12118.3 ETO09056.1 - 9.8 5.4 32.3 0.53 9.5 18.5 1.7 2 0 0 2 2 2 0 SprA-related family Nop14 PF04147.7 ETO09057.1 - 0.034 12.0 17.8 0.036 11.9 12.3 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 ETO09057.1 - 0.036 12.5 16.4 0.036 12.5 11.4 1.1 1 0 0 1 1 1 0 Daxx Family Ycf1 PF05758.7 ETO09057.1 - 0.21 9.2 5.9 0.23 9.1 4.1 1.1 1 0 0 1 1 1 0 Ycf1 CDC45 PF02724.9 ETO09057.1 - 0.31 9.0 11.2 0.33 8.9 7.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 ETO09057.1 - 0.35 10.1 15.1 0.45 9.8 10.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Prothymosin PF03247.9 ETO09057.1 - 0.76 9.9 34.3 0.033 14.3 19.9 1.5 2 0 0 2 2 1 0 Prothymosin/parathymosin family DUF2890 PF11081.3 ETO09057.1 - 0.85 9.6 16.2 1.1 9.2 11.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) SDA1 PF05285.7 ETO09057.1 - 1 8.6 19.2 1.2 8.3 13.3 1.1 1 0 0 1 1 1 0 SDA1 CENP-T PF15511.1 ETO09057.1 - 1.1 8.4 8.0 1.2 8.3 5.5 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T BUD22 PF09073.5 ETO09057.1 - 1.6 7.6 19.2 2 7.4 13.3 1.1 1 0 0 1 1 1 0 BUD22 GCIP PF13324.1 ETO09057.1 - 1.9 7.6 7.2 1.9 7.6 4.5 1.3 1 1 0 1 1 1 0 Grap2 and cyclin-D-interacting VID27 PF08553.5 ETO09057.1 - 2.1 6.4 15.0 2.5 6.1 10.4 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein CobT PF06213.7 ETO09057.1 - 2.1 7.4 18.0 3.3 6.7 12.5 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RRN3 PF05327.6 ETO09057.1 - 3 5.8 9.0 3.4 5.6 6.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 AIF_C PF14721.1 ETO09057.1 - 3.4 7.9 6.0 8.5 6.6 2.0 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Med8 PF10232.4 ETO09057.1 - 4.2 6.8 7.6 5.2 6.5 5.3 1.2 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Dicty_REP PF05086.7 ETO09057.1 - 6.4 4.3 15.4 9.5 3.8 10.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sporozoite_P67 PF05642.6 ETO09057.1 - 8.7 4.0 8.5 11 3.6 5.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Astro_capsid PF03115.9 ETO09057.1 - 9.6 4.3 7.9 12 3.9 5.5 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor SMI1_KNR4 PF09346.5 ETO09058.1 - 0.005 16.8 0.9 0.017 15.1 0.6 1.8 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.1 ETO09058.1 - 0.0056 17.1 0.5 0.0056 17.1 0.3 1.7 2 0 0 2 2 2 1 SMI1-KNR4 cell-wall Cullin PF00888.17 ETO09060.1 - 2.6e-125 419.2 18.1 3.4e-125 418.8 12.5 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 ETO09060.1 - 2.9e-26 91.0 1.7 2.9e-26 91.0 1.2 3.1 3 0 0 3 3 3 1 Cullin protein neddylation domain DUF2262 PF10020.4 ETO09060.1 - 0.00078 19.6 0.3 0.0028 17.8 0.2 2.1 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2262) WD40 PF00400.27 ETO09061.1 - 4e-41 137.4 16.7 9.4e-06 25.3 0.1 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat PHTB1_N PF14727.1 ETO09061.1 - 0.0035 16.3 0.0 0.055 12.4 0.0 2.2 2 0 0 2 2 2 1 PTHB1 N-terminus Pkinase_Tyr PF07714.12 ETO09062.1 - 0.03 13.3 0.3 3.8 6.4 0.0 2.1 1 1 1 2 2 2 0 Protein tyrosine kinase Pkinase PF00069.20 ETO09062.1 - 0.038 13.1 2.8 0.3 10.1 0.0 2.1 1 1 1 2 2 2 0 Protein kinase domain DUF2373 PF10180.4 ETO09062.1 - 0.46 10.0 5.0 0.23 11.0 0.8 2.3 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2373) Piwi PF02171.12 ETO09063.1 - 4.6e-40 137.4 0.0 7.5e-33 113.7 0.0 2.6 2 1 0 2 2 2 2 Piwi domain DUF4577 PF15145.1 ETO09063.1 - 0.085 12.7 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) Kelch_6 PF13964.1 ETO09064.1 - 3e-10 39.7 2.2 1.4e-06 28.2 0.2 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO09064.1 - 4.1e-07 29.4 6.4 0.00018 21.0 0.3 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO09064.1 - 1.9e-05 24.3 0.1 0.00088 18.9 0.0 3.5 4 0 0 4 4 4 1 Galactose oxidase, central domain N_Asn_amidohyd PF14736.1 ETO09064.1 - 0.031 13.1 0.0 0.12 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein N-terminal asparagine amidohydrolase Kelch_2 PF07646.10 ETO09064.1 - 0.035 13.8 0.6 1.4 8.7 0.0 3.2 3 0 0 3 3 3 0 Kelch motif Endonuclea_NS_2 PF13930.1 ETO09064.1 - 0.12 12.4 0.3 0.12 12.4 0.2 3.8 4 0 0 4 4 4 0 DNA/RNA non-specific endonuclease Kelch_5 PF13854.1 ETO09064.1 - 0.13 12.2 3.0 14 5.7 0.4 3.1 3 0 0 3 3 3 0 Kelch motif WD40 PF00400.27 ETO09065.1 - 2.5e-77 252.2 27.8 3.3e-11 42.6 0.0 7.0 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO09065.1 - 2.5e-10 39.1 6.7 0.017 13.2 0.1 5.2 1 1 4 5 5 5 5 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO09065.1 - 0.00054 19.4 0.1 0.0014 18.1 0.0 1.8 1 1 0 1 1 1 1 PQQ-like domain Nucleoporin_N PF08801.6 ETO09065.1 - 0.0019 17.0 23.5 0.51 9.0 0.3 5.3 1 1 2 4 4 4 4 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO09065.1 - 0.0081 14.5 0.9 3.9 5.6 0.1 2.8 1 1 2 3 3 3 3 Cytochrome D1 heme domain DUF1258 PF06869.7 ETO09065.1 - 0.027 13.5 3.2 13 4.7 0.1 3.6 1 1 2 4 4 4 0 Protein of unknown function (DUF1258) FtsK_SpoIIIE_N PF12538.3 ETO09065.1 - 0.063 13.3 2.8 0.2 11.7 0.2 2.3 1 1 0 2 2 2 0 DNA transporter Hira PF07569.6 ETO09065.1 - 0.13 11.4 3.6 13 4.8 0.0 3.7 3 2 1 5 5 5 0 TUP1-like enhancer of split Peptidase_M56 PF05569.6 ETO09066.1 - 0.01 14.8 4.2 0.019 13.9 0.1 2.4 2 0 0 2 2 2 0 BlaR1 peptidase M56 TauE PF01925.14 ETO09066.1 - 0.011 15.2 10.1 0.065 12.6 0.1 2.5 3 0 0 3 3 3 0 Sulfite exporter TauE/SafE TRAM1 PF08390.6 ETO09066.1 - 0.31 10.5 0.0 0.31 10.5 0.0 2.4 3 0 0 3 3 3 0 TRAM1-like protein EVC2_like PF12297.3 ETO09066.1 - 0.35 9.4 2.5 0.27 9.8 0.2 1.7 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein Vezatin PF12632.2 ETO09066.1 - 0.75 8.8 9.2 0.07 12.2 1.7 2.1 2 0 0 2 2 2 0 Mysoin-binding motif of peroxisomes DsbD_2 PF13386.1 ETO09066.1 - 1.7 8.3 12.0 0.14 11.8 1.6 2.8 2 1 0 2 2 2 0 Cytochrome C biogenesis protein transmembrane region Ctr PF04145.10 ETO09066.1 - 3.1 7.8 9.0 27 4.7 1.3 3.4 3 2 0 3 3 3 0 Ctr copper transporter family Baculo_11_kDa PF06143.6 ETO09066.1 - 3.5 7.0 6.4 5 6.5 0.1 3.3 4 0 0 4 4 4 0 Baculovirus 11 kDa family FA_desaturase PF00487.19 ETO09066.1 - 9.6 5.5 10.2 1.9 7.8 1.6 2.6 3 0 0 3 3 3 0 Fatty acid desaturase Peptidase_C14 PF00656.17 ETO09067.1 - 0.008 15.8 0.1 0.01 15.5 0.1 1.2 1 0 0 1 1 1 1 Caspase domain DUF3689 PF12463.3 ETO09068.1 - 0.082 11.6 2.5 0.095 11.4 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3689) Adenine_glyco PF03352.8 ETO09068.1 - 0.082 12.4 1.7 0.095 12.2 1.2 1.2 1 0 0 1 1 1 0 Methyladenine glycosylase DUF3901 PF13040.1 ETO09068.1 - 0.18 11.0 0.1 0.18 11.0 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3901) CemA PF03040.9 ETO09068.1 - 0.57 9.7 5.1 0.7 9.4 3.5 1.0 1 0 0 1 1 1 0 CemA family Kelch_6 PF13964.1 ETO09069.1 - 1.4e-08 34.5 9.3 0.00022 21.2 0.2 4.0 3 1 1 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO09069.1 - 1.9e-06 27.6 7.2 0.0028 17.5 0.3 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO09069.1 - 4.4e-05 23.1 8.3 0.095 12.4 0.5 3.9 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO09069.1 - 0.00043 19.7 11.3 0.0095 15.4 0.6 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO09069.1 - 0.002 18.2 4.7 0.017 15.2 0.1 3.7 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO09069.1 - 0.01 15.5 9.7 0.018 14.7 0.3 4.3 5 0 0 5 5 5 0 Kelch motif Phosphoprotein PF00922.12 ETO09070.1 - 0.081 12.1 5.2 0.093 11.9 3.6 1.1 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein MRP-S26 PF14943.1 ETO09070.1 - 0.09 12.3 7.5 0.11 11.9 5.2 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 PRTP PF01366.13 ETO09070.1 - 0.67 7.8 6.3 0.8 7.6 4.4 1.0 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Vfa1 PF08432.5 ETO09070.1 - 1.9 8.4 10.3 2.3 8.2 7.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 zf-CCCH_2 PF14608.1 ETO09072.1 - 0.092 12.7 5.8 0.4 10.7 1.4 3.1 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type WD40 PF00400.27 ETO09075.1 - 6.3e-164 526.7 47.0 3.5e-14 52.0 0.2 16.6 16 0 0 16 16 16 16 WD domain, G-beta repeat NACHT PF05729.7 ETO09075.1 - 8.7e-08 31.9 0.0 1.9e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETO09075.1 - 5e-05 23.4 0.0 0.00015 21.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETO09075.1 - 6e-05 23.3 0.0 6e-05 23.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain Pentapeptide_4 PF13599.1 ETO09075.1 - 0.00011 21.9 3.0 0.00036 20.2 2.1 1.9 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETO09075.1 - 0.00017 20.7 3.7 0.00039 19.5 2.6 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 ETO09075.1 - 0.00026 20.8 0.9 0.00099 18.9 0.6 2.0 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA_17 PF13207.1 ETO09075.1 - 0.0036 18.0 0.1 0.018 15.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 ETO09075.1 - 0.017 14.2 0.1 0.46 9.5 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin PD40 PF07676.7 ETO09075.1 - 0.027 14.1 9.2 10 5.8 0.2 6.0 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Chorion_2 PF03964.10 ETO09076.1 - 0.14 12.7 2.5 0.66 10.5 0.6 2.4 2 0 0 2 2 2 0 Chorion family 2 PIR PF00399.14 ETO09076.1 - 0.17 11.2 2.2 0.43 10.0 1.5 1.6 1 0 0 1 1 1 0 Yeast PIR protein repeat DUF2946 PF11162.3 ETO09078.1 - 1.1 9.4 3.9 0.29 11.3 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) PUF PF00806.14 ETO09079.1 - 0.00038 19.7 2.0 0.018 14.5 0.2 3.1 3 0 0 3 3 3 2 Pumilio-family RNA binding repeat NPP1 PF05630.6 ETO09081.1 - 6.6e-05 22.7 2.8 8.6e-05 22.3 1.9 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) 7tm_1 PF00001.16 ETO09082.1 - 2.5e-07 30.0 0.4 5e-07 29.1 0.2 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.6 ETO09082.1 - 5.7e-07 28.7 3.9 7.1e-07 28.4 2.7 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Git3 PF11710.3 ETO09082.1 - 0.00012 21.7 7.6 0.00026 20.6 5.3 1.4 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Frizzled PF01534.12 ETO09082.1 - 0.097 11.4 11.0 1.2 7.8 0.0 2.1 1 1 1 2 2 2 0 Frizzled/Smoothened family membrane region TPR_11 PF13414.1 ETO09083.1 - 1.2e-18 66.4 8.9 3e-11 42.8 0.9 2.8 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 ETO09083.1 - 1.6e-09 36.9 7.8 0.00021 20.9 0.2 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO09083.1 - 7e-09 34.9 8.8 0.00017 21.0 0.3 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO09083.1 - 1.2e-07 30.9 7.2 0.018 14.7 0.4 3.9 3 1 1 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 ETO09083.1 - 9.9e-06 25.6 3.5 9.9e-06 25.6 2.4 1.9 2 0 0 2 2 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 ETO09083.1 - 1e-05 26.0 2.0 0.0014 19.2 0.1 3.0 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 ETO09083.1 - 3.7e-05 23.5 8.9 0.00048 20.0 0.9 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETO09083.1 - 4.8e-05 23.1 0.3 0.00016 21.4 0.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO09083.1 - 0.00047 20.5 3.2 0.62 10.8 0.0 3.8 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO09083.1 - 0.0056 16.9 1.2 0.0056 16.9 0.8 4.0 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO09083.1 - 0.013 15.6 2.6 2.4 8.5 0.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETO09083.1 - 0.015 15.0 7.3 1.6 8.7 0.1 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.1 ETO09083.1 - 0.025 13.6 5.4 0.44 9.5 0.1 3.0 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 ETO09083.1 - 0.032 14.3 1.1 0.032 14.3 0.7 3.0 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO09083.1 - 0.11 13.0 11.3 17 6.1 0.6 4.9 5 2 1 6 6 4 0 Tetratricopeptide repeat DUF479 PF04336.7 ETO09083.1 - 0.51 10.4 4.1 2.5 8.2 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function, DUF479 DUF465 PF04325.8 ETO09083.1 - 5.2 6.8 12.0 0.97 9.1 0.6 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF465) Fis1_TPR_C PF14853.1 ETO09083.1 - 5.6 6.9 7.8 6.1 6.8 0.8 3.4 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Prefoldin_2 PF01920.15 ETO09083.1 - 6.5 6.5 12.8 0.078 12.7 1.3 2.9 2 1 1 3 3 3 0 Prefoldin subunit Pex14_N PF04695.8 ETO09084.1 - 0.54 10.3 3.5 1.7 8.7 0.1 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4558 PF15104.1 ETO09084.1 - 1.7 8.6 4.7 0.23 11.4 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4558) DUF1395 PF07160.7 ETO09085.1 - 1.1e-19 70.9 9.7 3.1e-14 53.0 1.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1395) DUF1880 PF08976.6 ETO09085.1 - 0.03 14.4 3.2 0.056 13.5 2.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1880) LexA_DNA_bind PF01726.11 ETO09088.1 - 0.051 13.1 0.3 0.31 10.6 0.1 2.1 2 0 0 2 2 2 0 LexA DNA binding domain DUF2779 PF11074.3 ETO09090.1 - 2.7 8.0 9.9 2.2 8.3 5.1 2.1 1 1 2 3 3 3 0 Domain of unknown function(DUF2779) WD40 PF00400.27 ETO09091.1 - 8.7e-62 202.9 25.6 8e-11 41.3 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO09091.1 - 3.7e-14 51.7 6.1 0.00014 20.1 0.1 5.9 2 2 3 6 6 6 5 Nucleoporin Nup120/160 HAD PF12710.2 ETO09091.1 - 0.00066 19.9 3.5 3.9 7.6 2.4 3.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PQQ_2 PF13360.1 ETO09091.1 - 0.059 12.8 0.8 2.3 7.5 0.0 2.7 3 1 0 3 3 3 0 PQQ-like domain TB2_DP1_HVA22 PF03134.14 ETO09091.1 - 0.13 12.0 2.4 0.2 11.4 1.6 1.3 1 0 0 1 1 1 0 TB2/DP1, HVA22 family DUF2179 PF10035.4 ETO09092.1 - 0.22 11.1 2.9 0.15 11.6 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2179) Serpin PF00079.15 ETO09093.1 - 5e-14 52.2 0.4 3.9e-13 49.3 0.3 1.9 1 1 0 1 1 1 1 Serpin (serine protease inhibitor) Phage_X PF05155.10 ETO09093.1 - 0.047 13.6 0.1 0.087 12.7 0.1 1.4 1 0 0 1 1 1 0 Phage X family GAGA_bind PF06217.7 ETO09095.1 - 2.2 8.1 26.3 3 7.7 18.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF87 PF01935.12 ETO09095.1 - 3.6 7.3 10.2 4.8 6.9 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 Herpes_DNAp_acc PF04929.7 ETO09095.1 - 9.1 5.1 19.0 14 4.5 13.1 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor TauD PF02668.11 ETO09096.1 - 6.5e-36 124.3 0.0 8.6e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 ETO09096.1 - 5.5e-05 23.5 0.1 0.00015 22.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF971) DUF4284 PF14112.1 ETO09097.1 - 0.0072 16.7 1.5 0.0072 16.7 1.1 1.8 1 1 0 2 2 2 1 Domain of unknown function (DUF4284) DUF2796 PF10986.3 ETO09097.1 - 0.051 13.5 5.5 0.091 12.7 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) NAM-associated PF14303.1 ETO09097.1 - 2.4 8.4 14.9 4.7 7.5 10.3 1.5 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain TBD PF12845.2 ETO09098.1 - 0.033 13.7 1.7 0.033 13.7 1.2 1.9 2 0 0 2 2 2 0 TBD domain DUF1120 PF06551.7 ETO09098.1 - 1.7 8.9 9.2 0.83 9.9 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1120) E1-E2_ATPase PF00122.15 ETO09099.1 - 1.8e-33 115.5 0.0 3.7e-33 114.4 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 ETO09099.1 - 1.5e-05 24.5 0.3 5.3e-05 22.8 0.2 1.9 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 ETO09099.1 - 4.5e-05 23.9 0.0 9.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETO09099.1 - 0.006 16.5 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit VBS PF08913.5 ETO09100.1 - 0.0045 17.2 0.4 0.0066 16.7 0.3 1.3 1 0 0 1 1 1 1 Vinculin Binding Site Translat_reg PF01818.12 ETO09100.1 - 0.053 13.0 0.4 0.078 12.5 0.3 1.2 1 0 0 1 1 1 0 Bacteriophage translational regulator YL1 PF05764.8 ETO09100.1 - 0.1 12.1 13.1 0.11 12.0 9.1 1.0 1 0 0 1 1 1 0 YL1 nuclear protein Presenilin PF01080.12 ETO09100.1 - 3.8 6.2 7.7 4.5 5.9 5.3 1.0 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.7 ETO09100.1 - 4.6 7.0 11.0 5.1 6.9 7.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EF-hand_6 PF13405.1 ETO09102.1 - 0.0054 16.5 0.0 0.018 14.8 0.0 2.0 1 1 0 1 1 1 1 EF-hand domain BNIP2 PF12496.3 ETO09102.1 - 0.012 15.7 5.1 0.015 15.4 3.5 1.2 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 YL1 PF05764.8 ETO09102.1 - 0.087 12.4 10.2 0.11 12.1 7.0 1.2 1 0 0 1 1 1 0 YL1 nuclear protein EF-hand_1 PF00036.27 ETO09102.1 - 0.11 11.8 0.1 0.28 10.5 0.1 1.7 1 0 0 1 1 1 0 EF hand PA26 PF04636.8 ETO09102.1 - 0.19 10.4 8.1 0.23 10.1 5.6 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Sporozoite_P67 PF05642.6 ETO09102.1 - 1.5 6.6 7.0 1.6 6.4 4.8 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CLASP_N PF12348.3 ETO09103.1 - 9.3e-20 70.9 0.6 1.9e-19 69.9 0.4 1.4 1 0 0 1 1 1 1 CLASP N terminal EF-hand_1 PF00036.27 ETO09103.1 - 1.3e-08 33.4 2.8 0.0069 15.6 0.1 4.1 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.1 ETO09103.1 - 8.1e-07 29.0 5.4 0.033 14.3 0.3 3.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO09103.1 - 5.3e-06 25.8 4.1 0.019 14.8 0.2 3.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 ETO09103.1 - 1.7e-05 24.3 5.5 0.00097 18.7 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain pair p25-alpha PF05517.7 ETO09103.1 - 0.018 15.2 3.1 3.6 7.8 0.1 2.8 1 1 1 2 2 2 0 p25-alpha HEAT_2 PF13646.1 ETO09103.1 - 0.024 14.9 0.0 1 9.6 0.0 3.0 3 1 0 3 3 3 0 HEAT repeats DUF1446 PF07287.6 ETO09103.1 - 0.028 12.8 0.0 0.046 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1446) G-alpha PF00503.15 ETO09104.1 - 3e-97 325.7 4.9 3.8e-97 325.4 3.4 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO09104.1 - 1e-10 41.1 0.3 1.6e-07 30.7 0.0 3.0 2 1 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 ETO09104.1 - 9.1e-06 26.1 0.6 0.21 12.0 0.0 2.7 2 1 0 2 2 2 2 Miro-like protein AAA_33 PF13671.1 ETO09104.1 - 0.00045 20.1 0.0 0.081 12.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 ETO09104.1 - 0.0016 18.4 0.5 0.16 11.9 0.3 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 ETO09104.1 - 0.0019 17.4 5.4 0.035 13.2 0.1 3.0 3 1 0 3 3 3 2 Gtr1/RagA G protein conserved region DUF815 PF05673.8 ETO09104.1 - 0.003 16.5 0.3 0.015 14.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ATP_bind_1 PF03029.12 ETO09104.1 - 0.0062 16.1 0.8 2.1 7.8 0.0 2.5 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 ETO09104.1 - 0.026 14.8 0.1 0.061 13.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 ETO09104.1 - 0.037 13.5 0.0 0.078 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.17 ETO09104.1 - 0.039 12.8 0.1 0.065 12.0 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain Ras PF00071.17 ETO09104.1 - 0.089 12.1 1.0 13 5.0 0.0 3.6 3 1 0 3 3 3 0 Ras family FtsK_SpoIIIE PF01580.13 ETO09104.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family ArfGap PF01412.13 ETO09105.1 - 9.5e-12 44.7 0.0 2.7e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TPR_11 PF13414.1 ETO09106.1 - 0.00025 20.6 0.4 0.00076 19.0 0.3 1.8 1 1 0 1 1 1 1 TPR repeat TPR_17 PF13431.1 ETO09106.1 - 0.016 15.3 0.1 0.12 12.6 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat FAT PF02259.18 ETO09106.1 - 0.034 13.1 2.9 0.1 11.5 2.0 1.8 1 1 0 1 1 1 0 FAT domain DMP1 PF07263.6 ETO09107.1 - 0.0027 16.5 3.0 0.0031 16.3 2.1 1.0 1 0 0 1 1 1 1 Dentin matrix protein 1 (DMP1) ADIP PF11559.3 ETO09107.1 - 0.017 15.0 21.1 0.023 14.6 14.6 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Ycf1 PF05758.7 ETO09107.1 - 0.02 12.6 8.5 0.023 12.4 5.9 1.0 1 0 0 1 1 1 0 Ycf1 DUF2347 PF09804.4 ETO09107.1 - 0.033 13.4 2.6 0.04 13.1 1.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) V_ATPase_I PF01496.14 ETO09107.1 - 0.1 10.4 9.0 0.12 10.2 6.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phage_GPO PF05929.6 ETO09107.1 - 0.11 11.7 6.4 0.12 11.5 4.4 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase IFT57 PF10498.4 ETO09107.1 - 0.13 10.9 16.3 0.17 10.6 11.3 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 HSP70 PF00012.15 ETO09107.1 - 0.37 8.6 9.6 0.42 8.4 6.6 1.0 1 0 0 1 1 1 0 Hsp70 protein DUF2229 PF09989.4 ETO09107.1 - 0.46 9.9 4.7 0.53 9.6 3.2 1.2 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF904 PF06005.7 ETO09107.1 - 0.48 10.7 28.6 0.11 12.7 5.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF904) TEX19 PF15553.1 ETO09107.1 - 0.6 9.9 2.8 0.76 9.6 2.0 1.2 1 0 0 1 1 1 0 Testis-expressed protein 19 TMF_TATA_bd PF12325.3 ETO09107.1 - 0.71 9.6 19.8 0.11 12.2 3.8 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding bZIP_1 PF00170.16 ETO09107.1 - 0.74 9.8 24.5 0.096 12.6 4.5 2.2 1 1 1 2 2 2 0 bZIP transcription factor APG6 PF04111.7 ETO09107.1 - 0.78 8.7 18.5 0.99 8.3 12.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 SprA-related PF12118.3 ETO09107.1 - 0.91 8.7 9.1 1.2 8.3 6.3 1.2 1 0 0 1 1 1 0 SprA-related family Rootletin PF15035.1 ETO09107.1 - 1.1 9.2 23.1 1.7 8.5 10.4 2.0 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion IncA PF04156.9 ETO09107.1 - 1.1 8.7 22.8 1.6 8.2 15.7 1.4 1 1 0 1 1 1 0 IncA protein Slu7 PF11708.3 ETO09107.1 - 1.3 8.6 14.0 1.8 8.2 9.7 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor RNA_pol_Rpb1_5 PF04998.12 ETO09107.1 - 1.4 8.0 3.8 1.7 7.8 2.7 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 GAGA_bind PF06217.7 ETO09107.1 - 2 8.2 6.3 2.5 7.9 4.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF342 PF03961.8 ETO09107.1 - 2.2 6.6 15.7 2.6 6.3 10.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TMPIT PF07851.8 ETO09107.1 - 3.3 6.7 7.9 3.9 6.4 5.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF2205 PF10224.4 ETO09107.1 - 3.7 7.1 17.2 9.6 5.8 0.4 2.7 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) Exonuc_VII_L PF02601.10 ETO09107.1 - 4.4 6.4 9.3 5.9 5.9 6.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit FAM60A PF15396.1 ETO09107.1 - 6.6 6.4 8.2 7.9 6.1 5.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF740 PF05340.7 ETO09107.1 - 7.1 4.8 8.9 7.5 4.7 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) bZIP_Maf PF03131.12 ETO09107.1 - 7.7 6.8 18.0 2.6 8.3 2.7 2.1 1 1 1 2 2 2 0 bZIP Maf transcription factor AhpC-TSA PF00578.16 ETO09109.1 - 3.5e-28 97.7 0.1 4.9e-28 97.2 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 ETO09109.1 - 1.1e-13 50.9 0.1 1.6e-13 50.4 0.1 1.3 1 1 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.1 ETO09109.1 - 0.00079 19.4 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like OTU PF02338.14 ETO09110.1 - 0.0044 17.5 0.0 0.7 10.4 0.0 3.0 2 0 0 2 2 2 1 OTU-like cysteine protease AAA_22 PF13401.1 ETO09110.1 - 0.037 14.1 0.0 0.19 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF1743 PF08489.6 ETO09110.1 - 0.041 13.6 0.0 0.4 10.4 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1743) AAA PF00004.24 ETO09110.1 - 0.075 13.2 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-Nse PF11789.3 ETO09111.1 - 0.45 10.0 2.4 0.93 9.0 1.6 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF1212 PF06738.7 ETO09112.1 - 0.51 9.7 4.0 0.77 9.1 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) Ste5_C PF12194.3 ETO09113.1 - 0.076 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein kinase Fus3-binding GTP_EFTU PF00009.22 ETO09113.1 - 0.12 11.8 0.4 0.34 10.3 0.2 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 ETO09114.1 - 0.0076 16.3 0.1 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu domain 2 TPR_12 PF13424.1 ETO09116.1 - 9.4e-38 128.0 11.3 2.4e-16 59.4 1.8 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO09116.1 - 1.4e-20 72.6 17.1 4e-09 35.9 2.1 3.5 2 2 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETO09116.1 - 6.2e-19 66.7 23.0 1e-05 24.9 0.8 5.4 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.1 ETO09116.1 - 9.7e-18 62.5 8.8 0.00017 21.1 0.0 4.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO09116.1 - 1.5e-17 62.0 19.7 0.0021 17.8 0.3 5.3 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETO09116.1 - 2.9e-15 55.6 0.1 0.00046 20.0 0.1 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO09116.1 - 2.8e-13 48.5 19.2 0.011 15.4 0.4 5.4 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.1 ETO09116.1 - 7.2e-06 26.1 0.0 12 6.8 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO09116.1 - 1.2e-05 25.4 4.8 4.9 7.8 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat zf-UBP PF02148.14 ETO09116.1 - 2.9e-05 24.0 0.2 0.0001 22.3 0.1 1.9 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein TPR_17 PF13431.1 ETO09116.1 - 0.0003 20.7 3.9 4.1 7.8 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO09116.1 - 0.0048 16.1 0.6 0.088 12.0 0.0 3.0 3 0 0 3 3 3 1 SHNi-TPR MIT PF04212.13 ETO09116.1 - 0.0066 16.3 5.8 4.4 7.2 0.4 4.2 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_16 PF13432.1 ETO09116.1 - 0.063 13.9 0.1 84 4.0 0.1 3.8 2 1 2 4 4 4 0 Tetratricopeptide repeat SLT PF01464.15 ETO09116.1 - 0.95 8.9 4.6 2.9 7.3 0.1 3.0 3 0 0 3 3 3 0 Transglycosylase SLT domain PyrBI_leader PF08052.6 ETO09117.1 - 0.064 13.0 0.6 0.23 11.2 0.0 2.3 2 0 0 2 2 2 0 PyrBI operon leader peptide WD40 PF00400.27 ETO09118.1 - 5.2e-30 102.2 16.4 2.1e-10 40.0 0.1 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO09118.1 - 8.6e-09 34.0 2.3 0.00077 17.7 1.1 2.8 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Glyphos_transf PF04464.9 ETO09118.1 - 0.0071 15.1 0.4 0.011 14.5 0.1 1.4 2 0 0 2 2 2 1 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase DUF4221 PF13970.1 ETO09118.1 - 0.072 12.3 2.1 0.24 10.6 1.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4221) DUF1100 PF06500.6 ETO09118.1 - 0.091 11.3 0.1 0.13 10.8 0.1 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) DUF1900 PF08954.6 ETO09118.1 - 0.1 12.0 0.0 2.7 7.4 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1900) WD40 PF00400.27 ETO09119.1 - 0.0009 19.0 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 WD domain, G-beta repeat zf-RING_2 PF13639.1 ETO09120.1 - 0.00026 20.7 2.1 0.00072 19.3 1.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO09120.1 - 0.0012 18.8 1.5 0.0077 16.2 1.0 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO09120.1 - 0.027 14.1 4.7 0.87 9.3 0.0 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 ETO09120.1 - 1.4 8.9 9.0 5.6 7.0 6.3 2.0 1 1 1 2 2 2 0 RING-like domain WD40 PF00400.27 ETO09121.1 - 4.2e-31 105.6 7.8 1.4e-10 40.5 0.3 4.4 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO09121.1 - 0.0072 14.5 0.1 0.2 9.7 0.0 2.3 1 1 2 3 3 3 3 Nucleoporin Nup120/160 fn3 PF00041.16 ETO09122.1 - 0.0011 19.0 1.6 0.037 14.1 0.1 3.0 2 2 0 2 2 2 2 Fibronectin type III domain Ras PF00071.17 ETO09123.1 - 2.8e-26 91.8 0.0 3.7e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.16 ETO09123.1 - 2.8e-09 36.4 0.0 3.8e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 ETO09123.1 - 2.8e-09 37.4 0.0 4.5e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 ETO09123.1 - 8.1e-06 25.3 0.0 4.7e-05 22.9 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 ETO09123.1 - 0.0016 17.6 0.0 0.0029 16.7 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 ETO09123.1 - 0.022 13.4 0.1 0.65 8.6 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit PEX-2N PF09263.5 ETO09123.1 - 0.047 14.0 0.0 0.68 10.2 0.0 2.1 2 0 0 2 2 2 0 Peroxisome biogenesis factor 1, N-terminal SAM_1 PF00536.25 ETO09123.1 - 0.094 12.9 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) MCM PF00493.18 ETO09123.1 - 0.1 11.3 0.1 0.6 8.8 0.0 1.9 2 0 0 2 2 2 0 MCM2/3/5 family Dicty_REP PF05086.7 ETO09125.1 - 0.59 7.8 6.4 0.5 8.0 4.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Isy1 PF06246.7 ETO09125.1 - 2.1 7.6 7.8 1.6 8.0 0.2 2.0 1 1 1 2 2 2 0 Isy1-like splicing family DUF3169 PF11368.3 ETO09127.1 - 0.1 11.7 7.9 0.073 12.2 4.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3169) DUF2207 PF09972.4 ETO09127.1 - 0.16 10.5 1.7 0.21 10.1 1.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4064 PF13273.1 ETO09127.1 - 0.81 9.8 8.3 5.7 7.1 2.5 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF4064) DUF3278 PF11683.3 ETO09127.1 - 2.6 8.0 7.7 0.86 9.5 2.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3278) TRP PF06011.7 ETO09127.1 - 5.5 5.4 17.4 0.014 14.0 5.0 1.8 2 1 1 3 3 3 0 Transient receptor potential (TRP) ion channel WD40 PF00400.27 ETO09128.1 - 2e-35 119.4 11.7 7.1e-12 44.7 0.3 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO09128.1 - 1.5e-06 26.6 2.5 0.034 12.3 0.0 3.5 1 1 3 4 4 4 3 Nucleoporin Nup120/160 TRCF PF03461.10 ETO09129.1 - 0.0045 16.9 0.0 0.0096 15.8 0.0 1.6 1 0 0 1 1 1 1 TRCF domain SID-1_RNA_chan PF13965.1 ETO09129.1 - 0.043 11.9 3.8 0.047 11.8 2.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Gastrin PF00918.12 ETO09129.1 - 0.046 14.5 0.4 0.13 13.1 0.3 1.8 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Ycf1 PF05758.7 ETO09129.1 - 0.065 10.9 10.9 0.074 10.7 7.6 1.2 1 0 0 1 1 1 0 Ycf1 Zip PF02535.17 ETO09129.1 - 0.15 11.0 4.6 0.17 10.8 3.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Mucin PF01456.12 ETO09129.1 - 0.43 10.3 5.7 0.62 9.8 4.0 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Hid1 PF12722.2 ETO09129.1 - 0.82 7.2 9.8 0.81 7.2 6.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Raftlin PF15250.1 ETO09129.1 - 0.96 7.8 9.9 1.2 7.5 6.8 1.3 1 0 0 1 1 1 0 Raftlin SDA1 PF05285.7 ETO09129.1 - 1.4 8.1 22.7 1.9 7.6 15.7 1.2 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 ETO09129.1 - 5.6 5.3 23.9 6.5 5.1 16.6 1.2 1 0 0 1 1 1 0 Daxx Family NOA36 PF06524.7 ETO09129.1 - 5.7 6.0 13.9 8.8 5.4 9.7 1.3 1 0 0 1 1 1 0 NOA36 protein Utp14 PF04615.8 ETO09129.1 - 6.3 4.8 29.5 6.8 4.7 20.4 1.0 1 0 0 1 1 1 0 Utp14 protein Serinc PF03348.10 ETO09129.1 - 6.8 5.2 6.6 9.3 4.8 4.6 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2422 PF10337.4 ETO09129.1 - 6.9 5.3 6.6 1.8 7.2 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2422) Nop14 PF04147.7 ETO09129.1 - 6.9 4.4 26.0 9.5 3.9 18.0 1.2 1 0 0 1 1 1 0 Nop14-like family ATAD4 PF15321.1 ETO09129.1 - 7 7.7 16.7 6.5e+02 1.4 11.6 2.6 1 1 0 1 1 1 0 ATPase family AAA domain containing 4 CT47 PF15623.1 ETO09129.1 - 7.4 6.2 29.9 10 5.7 20.7 1.3 1 0 0 1 1 1 0 Cancer/testis gene family 47 WD40 PF00400.27 ETO09130.1 - 3.1e-58 191.7 15.6 1.2e-09 37.6 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO09130.1 - 1.4e-13 49.9 9.6 0.0084 14.2 0.2 6.1 1 1 4 6 6 6 6 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO09130.1 - 0.0047 17.0 4.4 1.8 8.8 0.0 4.8 5 0 0 5 5 5 1 Kelch motif WD40 PF00400.27 ETO09131.1 - 3.3e-61 201.1 23.5 2.1e-10 40.0 0.5 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO09131.1 - 7.3e-11 40.9 7.7 0.067 11.3 0.0 5.9 1 1 4 6 6 6 6 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO09131.1 - 0.00011 21.1 14.9 0.057 12.1 0.1 3.9 1 1 2 3 3 3 3 Nup133 N terminal like DUF851 PF05867.6 ETO09131.1 - 0.0087 15.3 0.0 0.26 10.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF851) HAD PF12710.2 ETO09131.1 - 0.037 14.1 1.2 1.3 9.1 0.1 2.9 1 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Mitofilin PF09731.4 ETO09132.1 - 1.1 7.8 9.1 1.4 7.4 6.3 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MscS_porin PF12795.2 ETO09134.1 - 0.0012 18.2 6.7 0.0016 17.7 4.6 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain DUF3584 PF12128.3 ETO09134.1 - 0.0015 15.9 5.6 0.0018 15.7 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF342 PF03961.8 ETO09134.1 - 0.02 13.3 0.2 0.024 13.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SlyX PF04102.7 ETO09134.1 - 0.041 14.2 8.7 1.4 9.3 0.3 2.4 1 1 1 2 2 2 0 SlyX ATG16 PF08614.6 ETO09134.1 - 0.041 13.6 10.1 0.095 12.5 7.0 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) NYD-SP28_assoc PF14775.1 ETO09134.1 - 0.11 12.2 5.9 0.3 10.8 4.1 1.8 1 0 0 1 1 1 0 Sperm tail C-terminal domain APG6 PF04111.7 ETO09134.1 - 0.19 10.7 6.3 0.26 10.2 4.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 AcylCoA_dehyd_C PF12186.3 ETO09134.1 - 0.22 11.3 2.5 0.4 10.5 1.7 1.4 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase C terminal Atg14 PF10186.4 ETO09134.1 - 0.25 10.2 5.0 0.32 9.8 3.5 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2617 PF10936.3 ETO09134.1 - 0.32 10.5 2.6 0.97 8.9 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF2617 Phage_lysis PF03245.8 ETO09134.1 - 0.42 10.6 6.7 0.52 10.3 4.0 1.5 1 1 0 1 1 1 0 Bacteriophage Rz lysis protein DivIVA PF05103.8 ETO09134.1 - 0.69 9.9 8.0 1.5 8.8 5.5 1.6 1 1 0 1 1 1 0 DivIVA protein DUF948 PF06103.6 ETO09134.1 - 1.3 8.9 5.3 25 4.8 3.6 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 ETO09134.1 - 2.3 7.7 10.8 4.4 6.8 7.5 1.5 1 0 0 1 1 1 0 IncA protein Staphylokinase PF02821.11 ETO09135.1 - 0.54 10.0 11.9 1.6 8.4 2.9 2.3 1 1 0 2 2 2 0 Staphylokinase/Streptokinase family DUF3947 PF13135.1 ETO09135.1 - 5.7 7.2 8.3 5.6 7.2 4.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3947) ubiquitin PF00240.18 ETO09136.1 - 4e-14 51.7 0.1 7e-14 50.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 ETO09136.1 - 3.6e-06 26.5 0.0 6.4e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YtzH PF14165.1 ETO09137.1 - 0.08 13.1 1.6 0.19 12.0 1.1 1.6 1 0 0 1 1 1 0 YtzH-like protein zf-DHHC PF01529.15 ETO09139.1 - 0.016 14.6 0.1 0.026 13.9 0.1 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase Nucleoside_tran PF01733.13 ETO09139.1 - 0.087 11.9 3.4 0.08 12.0 0.4 1.8 1 1 1 2 2 2 0 Nucleoside transporter MyTH4 PF00784.12 ETO09140.1 - 2.4e-07 30.6 0.5 6.9e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 MyTH4 domain NapB PF03892.9 ETO09140.1 - 0.24 11.0 4.3 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Nitrate reductase cytochrome c-type subunit (NapB) PABP PF00658.13 ETO09142.1 - 0.06 13.0 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Poly-adenylate binding protein, unique domain Pox_A32 PF04665.7 ETO09143.1 - 0.32 10.2 5.0 3.1 7.0 0.4 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein VRR_NUC PF08774.6 ETO09144.1 - 2.1e-09 37.3 0.0 3.7e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 VRR-NUC domain PIP5K PF01504.13 ETO09145.1 - 4.9e-52 176.5 9.3 6.3e-51 172.8 6.5 2.0 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase ERCC4 PF02732.10 ETO09146.1 - 2.6e-17 62.9 0.0 7.8e-17 61.3 0.0 1.9 1 1 1 2 2 2 1 ERCC4 domain DUF515 PF04415.7 ETO09147.1 - 0.55 8.4 6.4 0.97 7.5 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF508 PF04370.7 ETO09147.1 - 4 7.0 10.5 9.3 5.8 7.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF508) LRR_4 PF12799.2 ETO09148.1 - 4.1e-10 39.0 29.3 0.0004 19.9 3.4 4.6 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO09148.1 - 7e-07 28.9 23.7 0.00054 19.6 3.1 4.0 3 1 1 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 ETO09148.1 - 3.2e-06 26.3 23.3 0.38 10.9 0.2 7.8 8 1 0 8 8 8 3 Leucine Rich Repeat TRCF PF03461.10 ETO09148.1 - 0.017 15.0 3.4 11 6.0 0.0 4.1 2 2 2 4 4 4 0 TRCF domain LRR_7 PF13504.1 ETO09148.1 - 0.4 11.0 22.6 18 6.1 0.3 6.5 6 0 0 6 6 6 0 Leucine rich repeat LRR_6 PF13516.1 ETO09148.1 - 4.5 7.6 22.9 43 4.6 0.5 6.4 5 1 1 6 6 6 0 Leucine Rich repeat WD40 PF00400.27 ETO09149.1 - 1.5e-08 34.2 5.0 0.0052 16.6 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 ETO09149.1 - 5.7e-05 22.8 0.2 0.38 10.5 0.0 4.4 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 ETO09149.1 - 0.0037 16.0 1.5 0.0047 15.7 0.1 1.8 2 0 0 2 2 2 1 Nup133 N terminal like Tricorn_PDZ PF14685.1 ETO09149.1 - 0.013 15.3 0.1 0.069 12.9 0.0 2.2 2 0 0 2 2 2 0 Tricorn protease PDZ domain DUF2217 PF10265.4 ETO09149.1 - 0.026 13.3 6.3 0.049 12.4 4.4 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF106 PF01956.11 ETO09151.1 - 0.045 13.2 0.0 0.045 13.2 0.0 3.1 2 1 0 2 2 2 0 Integral membrane protein DUF106 DUF4131 PF13567.1 ETO09151.1 - 0.064 12.6 0.1 0.064 12.6 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Borrelia_P83 PF05262.6 ETO09151.1 - 6.8 4.8 28.9 9.3 4.3 20.0 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein PLRV_ORF5 PF01690.12 ETO09151.1 - 7.3 5.6 22.9 11 5.0 15.9 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Sulfotransfer_3 PF13469.1 ETO09152.1 - 0.0039 18.1 0.0 0.007 17.3 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 ETO09152.1 - 0.01 15.1 1.5 0.025 13.8 1.0 1.7 1 1 0 1 1 1 0 Sulfotransferase domain zf-CCCH_2 PF14608.1 ETO09153.1 - 0.055 13.4 0.5 0.055 13.4 0.3 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type CAP_GLY PF01302.20 ETO09155.1 - 0.00011 21.8 0.0 0.00019 21.0 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Reo_sigmaC PF04582.7 ETO09155.1 - 0.017 14.3 9.8 0.031 13.4 3.6 2.3 2 1 0 2 2 2 0 Reovirus sigma C capsid protein Fez1 PF06818.10 ETO09155.1 - 1.8 8.5 46.9 0.59 10.1 22.4 2.5 1 1 1 2 2 2 0 Fez1 His_Phos_1 PF00300.17 ETO09155.1 - 7.9 6.5 11.0 0.92 9.5 0.6 2.8 2 1 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) WEMBL PF05701.6 ETO09155.1 - 8.5 4.7 61.9 0.0077 14.7 11.4 2.2 1 1 1 2 2 2 0 Weak chloroplast movement under blue light OST-HTH PF12872.2 ETO09156.1 - 3.4e-05 23.5 0.1 6.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 OST-HTH/LOTUS domain EphA2_TM PF14575.1 ETO09156.1 - 0.013 15.8 1.2 3 8.2 0.2 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Pex14_N PF04695.8 ETO09156.1 - 2.5 8.1 8.8 14 5.6 4.9 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TPR_2 PF07719.12 ETO09158.1 - 2.7 8.1 5.3 2.8 8.0 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat PQ-loop PF04193.9 ETO09159.1 - 1.2e-13 50.3 1.0 3.2e-13 48.9 0.7 1.7 1 0 0 1 1 1 1 PQ loop repeat IBR PF01485.16 ETO09160.1 - 0.00024 20.8 18.5 0.00081 19.2 4.6 2.7 2 0 0 2 2 2 2 IBR domain Zn_Tnp_IS91 PF14319.1 ETO09160.1 - 0.011 15.2 13.8 0.12 11.9 3.6 2.6 1 1 1 2 2 2 0 Transposase zinc-binding domain MEF2_binding PF09047.5 ETO09160.1 - 0.34 10.5 0.1 0.34 10.5 0.1 2.1 2 0 0 2 2 2 0 MEF2 binding zf-met PF12874.2 ETO09162.1 - 0.00099 19.2 1.2 0.014 15.5 0.0 3.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Mitofilin PF09731.4 ETO09162.1 - 0.75 8.3 20.1 0.95 8.0 13.9 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein LMBR1 PF04791.11 ETO09162.1 - 1.2 7.6 8.5 1.6 7.2 5.8 1.5 1 1 0 1 1 1 0 LMBR1-like membrane protein Secretin_N_2 PF07655.8 ETO09164.1 - 3.1 8.2 12.4 5.1 7.5 8.6 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain FliG_C PF01706.11 ETO09165.1 - 0.018 15.0 0.1 0.037 14.0 0.1 1.5 1 0 0 1 1 1 0 FliG C-terminal domain SAM_1 PF00536.25 ETO09167.1 - 3.2e-15 56.0 0.2 6.1e-15 55.1 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO09167.1 - 5.4e-14 51.7 0.1 1.4e-13 50.5 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CENP-T PF15511.1 ETO09167.1 - 7.7 5.6 19.8 0.46 9.6 8.8 2.1 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Kelch_6 PF13964.1 ETO09168.1 - 1.2e-08 34.7 2.4 0.0029 17.6 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO09168.1 - 5.1e-06 25.9 4.1 0.051 13.1 0.1 4.0 3 1 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 ETO09168.1 - 0.00057 19.9 0.2 1.5 9.0 0.0 4.1 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO09168.1 - 0.0038 17.1 4.0 0.064 13.2 0.6 3.6 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 ETO09168.1 - 0.012 15.3 4.1 6.2 6.7 0.2 4.2 4 0 0 4 4 4 0 Kelch motif Herpes_DNAp_acc PF04929.7 ETO09169.1 - 1.1 8.1 20.2 1.7 7.4 14.0 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF2201_N PF13203.1 ETO09169.1 - 1.1 8.3 13.3 1.7 7.7 9.2 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF1077 PF06417.7 ETO09170.1 - 0.11 11.8 1.2 0.21 10.9 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1077) TPR_2 PF07719.12 ETO09170.1 - 0.33 10.9 1.5 1.7 8.7 0.6 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat G-alpha PF00503.15 ETO09171.1 - 9e-25 87.1 1.1 1.1e-24 86.9 0.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit adh_short PF00106.20 ETO09173.1 - 1.1e-31 110.0 0.0 1.4e-31 109.6 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETO09173.1 - 2.3e-12 46.9 0.0 3.1e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETO09173.1 - 2.5e-11 43.8 0.1 3e-11 43.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 ETO09173.1 - 2.2e-05 24.5 0.0 4.2e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETO09173.1 - 0.00034 20.1 0.0 0.00065 19.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 ETO09173.1 - 0.0036 16.6 0.0 0.01 15.0 0.0 1.7 2 1 0 2 2 2 1 NmrA-like family RRM_1 PF00076.17 ETO09174.1 - 3.8e-14 52.0 0.0 8.2e-14 50.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO09174.1 - 4.4e-07 29.7 0.0 8.6e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO09174.1 - 0.00067 19.4 0.1 0.0011 18.7 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ldh_1_C PF02866.13 ETO09174.1 - 0.034 13.8 0.1 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain Leo1 PF04004.8 ETO09174.1 - 0.41 10.3 5.5 0.18 11.4 2.1 1.6 2 0 0 2 2 2 0 Leo1-like protein PHD PF00628.24 ETO09176.1 - 1.7e-09 37.1 10.8 1.7e-09 37.1 7.5 3.6 4 0 0 4 4 4 1 PHD-finger MetW PF07021.7 ETO09176.1 - 0.032 13.6 0.8 0.06 12.7 0.6 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW NPR3 PF03666.8 ETO09178.1 - 0.047 12.2 7.2 0.051 12.0 5.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Podoplanin PF05808.6 ETO09178.1 - 0.049 13.1 0.8 0.05 13.1 0.5 1.1 1 0 0 1 1 1 0 Podoplanin TMEM154 PF15102.1 ETO09178.1 - 0.36 10.5 10.6 0.15 11.7 1.6 2.1 1 1 1 2 2 2 0 TMEM154 protein family DUF612 PF04747.7 ETO09178.1 - 0.4 9.5 19.7 0.46 9.3 13.7 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF612 DUF2052 PF09747.4 ETO09178.1 - 0.44 10.4 5.1 0.45 10.4 3.5 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) FAM60A PF15396.1 ETO09178.1 - 0.56 9.9 9.0 0.63 9.7 6.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Sec16_N PF12935.2 ETO09178.1 - 0.58 10.0 13.6 0.66 9.8 9.4 1.0 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 N-terminus Presenilin PF01080.12 ETO09178.1 - 0.6 8.8 3.6 0.64 8.7 2.5 1.1 1 0 0 1 1 1 0 Presenilin Phyto_Pns9_10 PF05878.6 ETO09178.1 - 0.86 8.5 3.3 0.98 8.3 2.3 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 DUF572 PF04502.8 ETO09178.1 - 2.9 7.0 14.4 3.3 6.8 10.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF1387 PF07139.6 ETO09178.1 - 9.3 5.7 14.9 12 5.4 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) TRAPP PF04051.11 ETO09180.1 - 0.042 13.3 0.1 0.048 13.1 0.0 1.1 1 0 0 1 1 1 0 Transport protein particle (TRAPP) component RhoGAP PF00620.22 ETO09183.1 - 2e-23 82.7 0.0 3.5e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain CENP-B_dimeris PF09026.5 ETO09183.1 - 0.021 15.0 0.4 0.036 14.2 0.3 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain WD40 PF00400.27 ETO09184.1 - 2.5e-36 122.2 2.8 1.5e-08 34.1 0.2 6.9 6 1 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 ETO09184.1 - 6.9e-09 35.6 2.4 0.0001 22.0 0.0 3.7 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 ETO09184.1 - 1e-06 28.4 0.0 3.9e-06 26.5 0.0 1.9 2 1 0 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO09184.1 - 1.5e-05 23.4 2.0 0.0017 16.7 0.2 2.8 1 1 1 2 2 2 2 Cytochrome D1 heme domain PQQ PF01011.16 ETO09184.1 - 0.00091 18.6 0.0 1.4 8.5 0.0 3.5 4 0 0 4 4 4 2 PQQ enzyme repeat PD40 PF07676.7 ETO09184.1 - 0.06 13.0 4.6 19 5.0 0.0 4.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat IncA PF04156.9 ETO09185.1 - 0.01 15.4 22.2 0.016 14.7 15.4 1.3 1 0 0 1 1 1 0 IncA protein DUF3573 PF12097.3 ETO09185.1 - 0.13 10.8 11.6 0.15 10.6 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) SprA-related PF12118.3 ETO09185.1 - 0.29 10.4 15.3 0.37 10.0 10.6 1.2 1 0 0 1 1 1 0 SprA-related family CAF-1_p150 PF11600.3 ETO09185.1 - 0.69 9.2 36.8 0.98 8.7 25.5 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4407 PF14362.1 ETO09185.1 - 0.98 8.3 15.5 1.3 7.8 10.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Salp15 PF12115.3 ETO09185.1 - 1.4 9.1 7.3 1.9 8.7 5.1 1.3 1 0 0 1 1 1 0 Salivary protein of 15kDa inhibits CD4+ T cell activation DUF4613 PF15390.1 ETO09185.1 - 1.8 6.6 16.9 2.1 6.3 11.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Raptor_N PF14538.1 ETO09185.1 - 2.1 8.1 8.4 1.9 8.3 4.4 1.9 1 1 1 2 2 2 0 Raptor N-terminal CASPase like domain Atg14 PF10186.4 ETO09185.1 - 3.6 6.4 24.3 5.8 5.7 16.8 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Fib_alpha PF08702.5 ETO09185.1 - 4.5 7.3 27.9 4.3 7.4 8.7 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family MFMR PF07777.6 ETO09185.1 - 9.1 6.1 6.8 2.4 8.0 2.3 1.7 1 1 1 2 2 2 0 G-box binding protein MFMR HEAT_2 PF13646.1 ETO09186.1 - 0.00031 20.9 0.1 0.052 13.8 0.0 2.9 3 1 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 ETO09186.1 - 0.0013 19.1 0.3 3.2 8.3 0.0 3.5 2 1 1 3 3 3 2 HEAT-like repeat TIMELESS PF04821.9 ETO09187.1 - 2.9e-08 33.3 0.9 6e-08 32.2 0.1 1.8 2 0 0 2 2 2 1 Timeless protein ETRAMP PF09716.5 ETO09187.1 - 0.0069 16.3 2.4 0.096 12.6 0.5 2.3 2 0 0 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) FTP PF07504.8 ETO09187.1 - 0.014 14.8 0.2 0.033 13.6 0.2 1.6 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif PAXIP1_C PF15364.1 ETO09188.1 - 0.059 13.2 3.8 0.088 12.7 2.6 1.3 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein DUF2457 PF10446.4 ETO09188.1 - 0.14 10.8 10.0 0.17 10.5 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Senescence_reg PF04520.8 ETO09188.1 - 1.1 9.7 5.1 1.6 9.2 3.5 1.2 1 0 0 1 1 1 0 Senescence regulator Nucleo_P87 PF07267.6 ETO09188.1 - 5 5.6 5.8 6.9 5.2 4.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CAP_GLY PF01302.20 ETO09191.1 - 3.3e-274 885.2 128.3 3.2e-15 55.5 0.3 24.4 24 0 0 24 24 24 24 CAP-Gly domain Zip PF02535.17 ETO09193.1 - 0.00031 19.8 0.1 0.00044 19.3 0.0 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter PP_M1 PF03012.9 ETO09193.1 - 0.00087 18.7 6.4 0.0014 18.0 4.4 1.3 1 0 0 1 1 1 1 Phosphoprotein RP-C_C PF11800.3 ETO09193.1 - 0.25 11.0 2.2 0.39 10.3 1.5 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF3317 PF11779.3 ETO09193.1 - 0.98 8.9 4.7 1.6 8.2 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3317) Tetraspannin PF00335.15 ETO09193.1 - 2.2 7.4 7.5 26 3.9 5.2 2.2 1 1 0 1 1 1 0 Tetraspanin family DUF4094 PF13334.1 ETO09193.1 - 4.3 7.7 8.9 16 5.9 0.0 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) Tropomyosin_1 PF12718.2 ETO09194.1 - 2.9e-05 23.9 8.9 2.9e-05 23.9 6.1 3.2 4 0 0 4 4 4 2 Tropomyosin like EAP30 PF04157.11 ETO09194.1 - 0.0016 17.6 1.2 0.0016 17.6 0.8 3.9 3 2 1 4 4 4 1 EAP30/Vps36 family DUF3782 PF12644.2 ETO09194.1 - 0.0018 18.0 0.0 0.4 10.4 0.0 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3782) FTO_CTD PF12934.2 ETO09194.1 - 0.19 11.3 7.7 1.1 8.8 0.3 3.5 3 0 0 3 3 3 0 FTO C-terminal domain Laminin_II PF06009.7 ETO09194.1 - 0.39 10.4 16.9 0.019 14.6 2.9 3.6 3 1 1 4 4 4 0 Laminin Domain II IFT46_B_C PF12317.3 ETO09194.1 - 0.85 8.9 13.9 0.2 10.9 2.0 2.7 2 1 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal DUF745 PF05335.8 ETO09194.1 - 3 7.3 17.2 0.08 12.4 2.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF948 PF06103.6 ETO09194.1 - 3.2 7.6 11.9 6.5 6.6 0.5 4.5 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF4140 PF13600.1 ETO09194.1 - 5.1 7.5 6.7 16 6.0 0.9 3.1 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) ASL_C PF08328.6 ETO09194.1 - 6.8 6.5 8.8 0.51 10.1 1.7 2.4 2 1 0 2 2 2 0 Adenylosuccinate lyase C-terminal PH_10 PF15411.1 ETO09195.1 - 0.69 10.1 8.8 0.75 9.9 6.1 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain Ank_4 PF13637.1 ETO09197.1 - 1.7e-12 47.4 0.9 1.2e-06 28.8 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO09197.1 - 1.3e-09 37.9 0.1 9.4e-08 32.0 0.1 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO09197.1 - 2.6e-09 36.4 0.0 8.5e-07 28.6 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 ETO09197.1 - 4.4e-09 36.5 0.0 6e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO09197.1 - 2.1e-05 24.1 0.0 4.9e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat DUF294 PF03445.8 ETO09198.1 - 2.2e-05 24.0 0.0 2.6e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Putative nucleotidyltransferase DUF294 WD40 PF00400.27 ETO09199.1 - 2.3e-22 77.9 8.6 4.6e-11 42.1 0.1 4.2 4 1 0 4 4 4 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO09199.1 - 0.00038 18.7 0.8 0.19 9.7 0.0 2.5 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO09199.1 - 0.00074 18.3 0.8 0.39 9.4 0.0 2.3 2 0 0 2 2 2 2 Nup133 N terminal like Kelch_1 PF01344.20 ETO09200.1 - 1.5e-07 30.8 0.7 0.0013 18.2 0.1 4.0 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETO09200.1 - 2.4e-05 23.9 0.8 0.02 14.6 0.0 3.5 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO09200.1 - 0.00072 19.6 1.0 0.0048 17.0 0.1 2.9 3 0 0 3 3 2 1 Kelch motif Kelch_2 PF07646.10 ETO09200.1 - 0.0028 17.3 2.9 0.0084 15.8 0.1 3.0 4 0 0 4 4 4 1 Kelch motif RNA_pol_3_Rpc31 PF11705.3 ETO09200.1 - 0.0033 17.3 20.3 0.0078 16.1 14.1 1.7 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.9 ETO09200.1 - 0.071 11.1 22.0 0.098 10.6 15.2 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 ETO09200.1 - 0.69 8.5 35.7 0.92 8.1 24.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DDHD PF02862.12 ETO09200.1 - 0.95 9.2 7.4 1.5 8.6 5.1 1.3 1 0 0 1 1 1 0 DDHD domain DUF1510 PF07423.6 ETO09200.1 - 1.4 8.2 24.4 2.4 7.4 16.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2722 PF10846.3 ETO09200.1 - 2.3 7.1 11.7 1.4 7.8 6.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Astro_capsid PF03115.9 ETO09200.1 - 3.7 5.6 11.0 5.3 5.1 7.6 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Vfa1 PF08432.5 ETO09200.1 - 7.9 6.4 22.4 16 5.4 15.5 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PseudoU_synth_2 PF00849.17 ETO09201.1 - 1.6e-13 50.8 0.2 1.6e-13 50.8 0.2 2.3 2 2 0 2 2 2 1 RNA pseudouridylate synthase DUF3884 PF13024.1 ETO09201.1 - 0.19 11.1 1.4 0.94 8.9 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3884) PseudoU_synth_2 PF00849.17 ETO09202.1 - 0.31 10.8 2.7 0.36 10.6 0.7 1.9 2 1 0 2 2 2 0 RNA pseudouridylate synthase Pox_RNA_Pol_19 PF05320.7 ETO09202.1 - 0.33 10.7 4.5 0.17 11.6 1.7 1.5 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Securin PF04856.8 ETO09202.1 - 0.63 9.7 5.8 0.38 10.4 3.1 1.3 1 1 0 1 1 1 0 Securin sister-chromatid separation inhibitor Apc15p PF05841.6 ETO09202.1 - 1.3 9.7 5.4 0.32 11.7 1.8 1.4 2 0 0 2 2 2 0 Apc15p protein PARP PF00644.15 ETO09203.1 - 5.1e-27 94.6 0.1 9.8e-25 87.1 0.0 2.7 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.15 ETO09203.1 - 3.9e-06 26.1 0.6 1.2e-05 24.6 0.4 1.8 1 0 0 1 1 1 1 WWE domain DUF2470 PF10615.4 ETO09203.1 - 0.054 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2470) DUF2116 PF09889.4 ETO09204.1 - 0.022 14.5 1.2 0.022 14.5 0.8 1.9 1 1 1 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Ribosomal_L13 PF00572.13 ETO09204.1 - 0.058 13.4 3.8 0.06 13.4 2.6 1.1 1 0 0 1 1 1 0 Ribosomal protein L13 DUF3899 PF13038.1 ETO09204.1 - 0.34 11.0 2.7 0.38 10.9 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) Protocadherin PF08374.6 ETO09204.1 - 2.1 7.8 5.1 2.3 7.8 3.6 1.1 1 0 0 1 1 1 0 Protocadherin WD40 PF00400.27 ETO09205.1 - 0.0006 19.6 0.7 0.0006 19.6 0.5 3.2 4 0 0 4 4 4 1 WD domain, G-beta repeat CPSF_A PF03178.10 ETO09205.1 - 0.012 14.7 0.2 0.096 11.7 0.1 2.2 2 0 0 2 2 2 0 CPSF A subunit region Daxx PF03344.10 ETO09205.1 - 0.062 11.7 23.3 0.092 11.2 16.1 1.2 1 0 0 1 1 1 0 Daxx Family TFIIF_alpha PF05793.7 ETO09205.1 - 0.63 8.3 32.4 1.2 7.4 22.5 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ribosomal_60s PF00428.14 ETO09205.1 - 3.9 7.9 15.9 14 6.1 1.9 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein Peptidase_M20 PF01546.23 ETO09206.1 - 5.8e-22 78.1 0.6 9.3e-22 77.4 0.4 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Pkinase PF00069.20 ETO09207.1 - 1.9e-12 46.8 0.1 2.7e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO09207.1 - 0.085 11.9 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase KH_1 PF00013.24 ETO09209.1 - 4.8e-13 48.5 1.3 4.8e-12 45.3 0.1 2.2 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 ETO09209.1 - 2.6e-07 30.1 0.0 5.2e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 KH domain BEX PF04538.7 ETO09209.1 - 0.027 14.6 0.9 0.068 13.3 0.2 1.9 2 0 0 2 2 2 0 Brain expressed X-linked like family DUF3480 PF11979.3 ETO09209.1 - 0.05 12.2 0.3 0.078 11.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3480) DUF605 PF04652.11 ETO09209.1 - 0.059 12.7 7.3 0.071 12.5 5.1 1.1 1 0 0 1 1 1 0 Vta1 like KH_2 PF07650.12 ETO09209.1 - 0.069 12.7 0.1 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 KH domain Zip PF02535.17 ETO09210.1 - 0.034 13.1 0.0 0.034 13.1 0.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter FAM176 PF14851.1 ETO09210.1 - 0.059 13.0 0.4 0.08 12.6 0.3 1.1 1 0 0 1 1 1 0 FAM176 family EMP70 PF02990.11 ETO09211.1 - 7.9e-149 496.4 26.3 7.9e-149 496.4 18.2 1.4 2 0 0 2 2 2 1 Endomembrane protein 70 Collar PF07484.7 ETO09211.1 - 0.067 12.9 0.0 0.22 11.3 0.0 1.8 1 0 0 1 1 1 0 Phage Tail Collar Domain DUF1182 PF06681.8 ETO09212.1 - 0.067 12.4 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1182) Zip PF02535.17 ETO09212.1 - 1.2 8.1 7.8 1.5 7.7 5.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TCP PF03634.8 ETO09212.1 - 3.4 8.0 9.7 0.36 11.2 3.8 1.5 2 0 0 2 2 2 0 TCP family transcription factor SelP_N PF04592.9 ETO09212.1 - 3.6 6.9 14.2 5.9 6.2 9.8 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Macoilin PF09726.4 ETO09212.1 - 8.3 4.5 13.8 13 3.8 9.6 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF2796 PF10986.3 ETO09213.1 - 0.0038 17.2 2.1 0.03 14.2 0.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2796) Dyp_perox PF04261.7 ETO09214.1 - 0.00034 19.4 0.0 0.00048 18.9 0.0 1.3 1 0 0 1 1 1 1 Dyp-type peroxidase family DUF4045 PF13254.1 ETO09215.1 - 0.25 10.5 11.5 0.34 10.1 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PAT1 PF09770.4 ETO09215.1 - 0.28 9.3 35.2 0.33 9.1 24.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 ETO09215.1 - 0.56 8.3 38.7 0.67 8.0 26.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal GAGA_bind PF06217.7 ETO09215.1 - 0.66 9.8 11.2 0.82 9.5 7.8 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family YqfD PF06898.6 ETO09215.1 - 1.7 7.2 7.3 20 3.7 4.6 2.0 2 0 0 2 2 2 0 Putative stage IV sporulation protein YqfD Peptidase_C78 PF07910.8 ETO09216.1 - 0.0028 16.7 0.2 0.41 9.7 0.0 2.2 2 0 0 2 2 2 1 Peptidase family C78 APG6 PF04111.7 ETO09216.1 - 0.0046 16.0 10.1 0.0068 15.4 7.0 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 IFT57 PF10498.4 ETO09216.1 - 0.027 13.2 16.5 0.042 12.5 11.4 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Speriolin_N PF15058.1 ETO09216.1 - 0.056 13.3 1.8 0.13 12.1 0.9 1.7 1 1 1 2 2 2 0 Speriolin N terminus Pox_A_type_inc PF04508.7 ETO09216.1 - 0.071 12.9 2.4 17 5.4 0.0 3.8 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DUF3450 PF11932.3 ETO09216.1 - 0.073 12.3 15.3 0.35 10.0 5.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) RP-C_C PF11800.3 ETO09216.1 - 0.079 12.6 3.4 0.12 12.0 2.4 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Tenui_N PF05733.6 ETO09216.1 - 0.11 11.8 3.5 0.052 12.8 0.2 1.9 1 1 1 2 2 2 0 Tenuivirus/Phlebovirus nucleocapsid protein CCDC155 PF14662.1 ETO09216.1 - 0.14 11.7 16.8 0.22 11.0 11.6 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 CENP-F_leu_zip PF10473.4 ETO09216.1 - 0.14 11.9 20.7 0.5 10.2 13.6 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1192 PF06698.6 ETO09216.1 - 0.18 11.6 6.6 0.36 10.6 0.5 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1192) YjgP_YjgQ PF03739.9 ETO09216.1 - 0.21 10.3 0.7 0.24 10.1 0.5 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family PEP-utilisers_N PF05524.8 ETO09216.1 - 0.22 11.3 7.5 0.4 10.4 1.0 2.2 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal DUF3584 PF12128.3 ETO09216.1 - 0.22 8.7 12.8 0.29 8.3 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2433 PF10360.4 ETO09216.1 - 0.35 11.1 4.0 1.4 9.2 2.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2433) DUF3338 PF11819.3 ETO09216.1 - 0.44 9.9 10.5 0.49 9.8 1.7 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF3338) PspA_IM30 PF04012.7 ETO09216.1 - 0.48 9.7 17.9 1.6 8.0 6.2 2.2 1 1 1 2 2 2 0 PspA/IM30 family Sec20 PF03908.8 ETO09216.1 - 0.64 9.7 9.2 0.078 12.6 2.4 2.1 2 0 0 2 2 2 0 Sec20 PEPcase_2 PF14010.1 ETO09216.1 - 0.67 8.2 5.4 0.85 7.8 3.8 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Rootletin PF15035.1 ETO09216.1 - 0.8 9.6 15.3 2.3 8.1 10.7 1.6 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Syntaxin-6_N PF09177.6 ETO09216.1 - 1 9.7 9.4 3.2 8.2 6.5 1.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal ApoC-I PF04691.7 ETO09216.1 - 1 9.0 7.2 6.9 6.4 1.8 2.4 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) Prefoldin PF02996.12 ETO09216.1 - 1.4 8.5 17.1 3.6e+02 0.8 11.8 3.5 1 1 0 1 1 1 0 Prefoldin subunit BLOC1_2 PF10046.4 ETO09216.1 - 1.6 8.8 14.8 2.2 8.4 0.7 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HALZ PF02183.13 ETO09216.1 - 1.9 8.2 11.3 0.62 9.8 1.3 3.2 3 1 0 3 3 3 0 Homeobox associated leucine zipper Baculo_PEP_C PF04513.7 ETO09216.1 - 2.1 8.1 10.1 1.5 8.6 0.1 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FliL PF03748.9 ETO09216.1 - 2.2 8.3 7.2 2.1 8.4 4.1 1.6 1 1 0 1 1 1 0 Flagellar basal body-associated protein FliL Spc7 PF08317.6 ETO09216.1 - 2.4 6.7 19.0 11 4.6 12.5 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF1640 PF07798.6 ETO09216.1 - 2.6 8.0 18.5 6.5 6.7 12.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) ERM PF00769.14 ETO09216.1 - 2.7 7.4 18.8 5 6.5 13.0 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family CENP-Q PF13094.1 ETO09216.1 - 4.5 7.2 18.4 27 4.7 12.8 2.3 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Syntaxin PF00804.20 ETO09216.1 - 9.9 6.3 15.2 3.2e+03 -1.7 10.5 2.5 1 1 0 1 1 1 0 Syntaxin DUF342 PF03961.8 ETO09216.1 - 9.9 4.4 13.9 31 2.8 9.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Kelch_6 PF13964.1 ETO09218.1 - 1.3e-06 28.2 4.8 2.1e-06 27.6 0.1 3.3 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 ETO09218.1 - 1.1e-05 24.8 0.4 1.1e-05 24.8 0.3 3.9 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 ETO09218.1 - 0.00046 20.2 0.1 0.0075 16.4 0.0 2.6 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO09218.1 - 0.0012 18.5 5.0 0.0037 16.9 0.1 3.8 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 ETO09218.1 - 0.013 15.4 1.3 0.013 15.4 0.9 2.2 2 0 0 2 2 2 0 Kelch motif Glyco_hydro_38 PF01074.17 ETO09219.1 - 1.1e-44 152.7 9.7 3.1e-44 151.2 6.8 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 ETO09219.1 - 6.8e-14 51.5 0.0 1.2e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 ETO09219.1 - 1.7e-05 24.9 0.0 4.7e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Inhibitor_I29 PF08246.7 ETO09220.1 - 6.8e-17 61.4 6.7 6.8e-17 61.4 4.6 1.6 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Cytochrom_C1 PF02167.10 ETO09222.1 - 2.7e-47 161.2 0.0 3.2e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Med31 PF05669.7 ETO09223.1 - 1.3e-19 69.7 24.1 1.1e-13 50.8 7.5 3.8 2 1 1 3 3 3 2 SOH1 DUF2109 PF09882.4 ETO09224.1 - 0.081 12.8 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2109) DUF2162 PF09930.4 ETO09225.1 - 0.2 10.7 0.5 0.31 10.1 0.4 1.2 1 0 0 1 1 1 0 Predicted transporter (DUF2162) BLOC1_2 PF10046.4 ETO09226.1 - 0.017 15.2 1.6 0.017 15.2 1.1 3.4 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DMAP_binding PF06464.6 ETO09226.1 - 0.022 15.3 1.2 0.059 13.9 0.8 1.7 1 0 0 1 1 1 0 DMAP1-binding Domain Aminotran_5 PF00266.14 ETO09226.1 - 0.039 12.6 2.1 1.2 7.8 0.0 2.1 1 1 1 2 2 2 0 Aminotransferase class-V DHquinase_II PF01220.14 ETO09226.1 - 0.053 12.8 2.3 0.064 12.5 0.4 2.0 2 0 0 2 2 2 0 Dehydroquinase class II CAP_N PF01213.14 ETO09226.1 - 0.078 12.2 1.4 0.12 11.6 1.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF148 PF02520.12 ETO09226.1 - 0.14 11.9 17.1 0.63 9.8 3.6 3.0 2 1 1 3 3 3 0 Domain of unknown function DUF148 DUF4407 PF14362.1 ETO09226.1 - 0.25 10.2 4.8 0.16 10.8 2.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) COG5 PF10392.4 ETO09226.1 - 0.27 11.2 9.2 0.05 13.5 2.2 2.7 3 1 1 4 4 4 0 Golgi transport complex subunit 5 DEAD PF00270.24 ETO09226.1 - 0.53 9.7 4.6 2.6 7.5 3.2 2.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase GAS PF13851.1 ETO09226.1 - 0.93 8.6 21.2 0.094 11.8 10.6 2.2 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding ASL_C PF08328.6 ETO09226.1 - 1.1 9.1 6.8 0.26 11.1 1.9 2.1 2 1 1 3 3 3 0 Adenylosuccinate lyase C-terminal OSCP PF00213.13 ETO09226.1 - 1.2 9.0 11.8 0.12 12.2 0.6 3.0 1 1 2 3 3 3 0 ATP synthase delta (OSCP) subunit FNIP_M PF14637.1 ETO09226.1 - 1.8 8.0 6.9 1.6 8.2 3.4 1.9 2 1 0 2 2 2 0 Folliculin-interacting protein middle domain NPV_P10 PF05531.7 ETO09226.1 - 2.1 8.6 10.3 1.3 9.3 1.5 3.5 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Nsp1_C PF05064.8 ETO09226.1 - 7.3 6.2 13.9 2.6 7.7 3.2 3.4 2 1 2 4 4 4 0 Nsp1-like C-terminal region Pkr1 PF08636.5 ETO09227.1 - 2e-07 30.9 2.5 3.6e-07 30.1 1.7 1.3 1 0 0 1 1 1 1 ER protein Pkr1 DUF4131 PF13567.1 ETO09227.1 - 0.016 14.6 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) PLA2_B PF01735.13 ETO09227.1 - 0.086 10.9 0.4 0.11 10.6 0.3 1.1 1 0 0 1 1 1 0 Lysophospholipase catalytic domain Sporozoite_P67 PF05642.6 ETO09227.1 - 0.19 9.5 3.9 0.25 9.1 2.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Kei1 PF08552.6 ETO09228.1 - 0.026 14.2 0.3 0.026 14.2 0.2 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 PDZ_2 PF13180.1 ETO09229.1 - 4.7e-07 29.5 0.0 2.6e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.19 ETO09229.1 - 0.00033 20.7 0.2 0.00097 19.2 0.1 1.8 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) Sporozoite_P67 PF05642.6 ETO09230.1 - 0.027 12.3 4.2 0.034 12.0 2.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3439 PF11921.3 ETO09230.1 - 0.46 10.2 7.1 0.87 9.3 4.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) WD40 PF00400.27 ETO09232.1 - 2.8e-163 524.6 45.5 3.3e-13 48.9 0.1 15.4 15 0 0 15 15 15 15 WD domain, G-beta repeat Nup160 PF11715.3 ETO09232.1 - 1.9e-10 39.5 32.9 0.38 8.8 0.2 11.4 2 1 8 10 10 10 6 Nucleoporin Nup120/160 Str_synth PF03088.11 ETO09232.1 - 3.2e-08 33.5 2.0 0.94 9.5 0.0 8.3 7 3 2 9 9 9 1 Strictosidine synthase Pentapeptide_4 PF13599.1 ETO09232.1 - 3.7e-06 26.6 0.2 1.2e-05 25.0 0.1 1.9 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Cytochrom_D1 PF02239.11 ETO09232.1 - 9.8e-06 24.1 3.9 1.4 7.0 0.0 6.0 4 1 2 7 7 7 2 Cytochrome D1 heme domain DUF1258 PF06869.7 ETO09232.1 - 4.6e-05 22.6 6.9 1.2 8.1 0.2 6.7 4 2 3 8 8 8 2 Protein of unknown function (DUF1258) Pentapeptide_3 PF13576.1 ETO09232.1 - 0.00013 21.8 0.8 0.0005 19.8 0.5 2.1 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETO09232.1 - 0.00027 20.0 5.1 0.00067 18.8 3.6 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) PD40 PF07676.7 ETO09232.1 - 0.00048 19.7 38.9 2.7 7.7 0.1 12.4 14 0 0 14 14 14 2 WD40-like Beta Propeller Repeat GATase PF00117.23 ETO09232.1 - 0.0034 16.8 1.1 20 4.5 0.0 5.4 4 2 1 6 6 6 0 Glutamine amidotransferase class-I PLD_C PF12357.3 ETO09232.1 - 0.012 15.0 0.1 19 4.8 0.0 5.8 7 1 0 7 7 7 0 Phospholipase D C terminal DUF3255 PF11631.3 ETO09232.1 - 0.019 14.5 0.2 26 4.4 0.0 4.9 5 2 2 7 7 7 0 Protein of unknown function (DUF3255) mRNA_cap_C PF03919.10 ETO09232.1 - 0.24 11.7 5.4 31 4.9 0.0 5.7 6 1 1 7 7 7 0 mRNA capping enzyme, C-terminal domain DUF1510 PF07423.6 ETO09234.1 - 1e-05 25.0 9.0 2e-05 24.1 6.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) CDC45 PF02724.9 ETO09234.1 - 2.3e-05 22.6 1.9 2.3e-05 22.6 1.3 1.1 1 0 0 1 1 1 1 CDC45-like protein RNase_H2-Ydr279 PF09468.5 ETO09234.1 - 0.0055 15.9 9.0 0.0055 15.9 6.3 1.6 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) SID-1_RNA_chan PF13965.1 ETO09234.1 - 0.047 11.8 0.7 0.064 11.4 0.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Tim54 PF11711.3 ETO09234.1 - 0.056 12.0 8.0 0.082 11.4 5.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Zip PF02535.17 ETO09234.1 - 0.072 12.0 0.4 0.096 11.6 0.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2201_N PF13203.1 ETO09234.1 - 0.12 11.5 5.3 0.15 11.1 3.7 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Ycf1 PF05758.7 ETO09234.1 - 0.12 10.0 16.5 0.52 7.9 11.4 1.6 1 1 0 1 1 1 0 Ycf1 MRP-L46 PF11788.3 ETO09234.1 - 0.3 11.7 13.3 0.17 12.5 7.9 1.5 1 1 0 1 1 1 0 39S mitochondrial ribosomal protein L46 Drc1-Sld2 PF11719.3 ETO09234.1 - 0.32 10.0 23.3 1.3 8.0 12.6 2.0 2 0 0 2 2 2 0 DNA replication and checkpoint protein SMN PF06003.7 ETO09234.1 - 0.36 9.8 6.4 0.045 12.8 1.8 1.5 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) RP-C_C PF11800.3 ETO09234.1 - 0.69 9.5 8.5 3 7.5 4.6 2.0 2 0 0 2 2 2 0 Replication protein C C-terminal region YqfQ PF14181.1 ETO09234.1 - 1.2 9.1 18.1 1.9 8.4 12.5 1.3 1 0 0 1 1 1 0 YqfQ-like protein RR_TM4-6 PF06459.7 ETO09234.1 - 1.5 8.6 13.2 2.3 8.0 9.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_polI_A34 PF08208.6 ETO09234.1 - 1.7 8.2 28.9 3.4 7.3 20.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 HSP90 PF00183.13 ETO09234.1 - 3.6 5.8 16.7 5 5.3 11.6 1.2 1 0 0 1 1 1 0 Hsp90 protein Gag_spuma PF03276.9 ETO09234.1 - 4.7 5.4 9.0 6.2 5.0 6.2 1.2 1 0 0 1 1 1 0 Spumavirus gag protein ETRAMP PF09716.5 ETO09234.1 - 4.8 7.1 10.0 2.1 8.3 4.6 2.1 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Aegerolysin PF06355.8 ETO09235.1 - 3.4e-27 94.8 0.8 3.4e-27 94.8 0.6 1.8 2 0 0 2 2 2 1 Aegerolysin IIGP PF05049.8 ETO09235.1 - 6.6e-25 87.7 0.3 8.7e-25 87.3 0.2 1.1 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.18 ETO09235.1 - 2.8e-05 24.0 0.0 5e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 ETO09235.1 - 0.00011 22.6 0.0 0.00034 21.1 0.0 1.8 2 1 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 ETO09235.1 - 0.00035 19.8 0.0 0.00056 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 ETO09235.1 - 0.0017 18.6 0.1 0.0025 18.1 0.1 1.5 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 ETO09235.1 - 0.0068 15.9 0.0 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Septin PF00735.13 ETO09235.1 - 0.013 14.5 0.1 0.12 11.4 0.0 2.2 2 1 0 2 2 2 0 Septin AAA_23 PF13476.1 ETO09235.1 - 0.044 14.1 1.4 0.052 13.8 0.2 1.7 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 ETO09235.1 - 0.057 13.2 0.9 0.92 9.3 0.6 2.5 1 1 0 1 1 1 0 Dynamin family IstB_IS21 PF01695.12 ETO09235.1 - 0.077 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Ras PF00071.17 ETO09235.1 - 0.089 12.1 0.6 2 7.7 0.0 2.5 2 1 0 2 2 2 0 Ras family AAA_17 PF13207.1 ETO09235.1 - 0.12 13.2 0.2 0.28 11.9 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETO09235.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.1 ETO09235.1 - 0.2 11.5 0.0 0.2 11.5 0.0 2.6 3 0 0 3 3 3 0 AAA domain WD40 PF00400.27 ETO09236.1 - 1.8e-26 90.9 9.0 1.5e-08 34.2 0.5 3.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO09236.1 - 0.00034 18.8 1.4 0.17 10.0 0.0 2.7 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO09236.1 - 0.022 13.5 5.4 0.6 8.7 3.8 2.5 1 1 0 1 1 1 0 Nup133 N terminal like DUF912 PF06024.7 ETO09237.1 - 0.015 15.2 0.6 0.018 15.0 0.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3899 PF13038.1 ETO09237.1 - 0.041 14.0 7.6 0.047 13.8 5.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) UPF0233 PF06781.7 ETO09237.1 - 0.043 13.4 1.1 0.046 13.3 0.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) DUF2956 PF11169.3 ETO09237.1 - 0.056 13.4 10.7 0.058 13.3 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) DBINO PF13892.1 ETO09237.1 - 0.056 13.4 14.6 0.055 13.5 10.1 1.1 1 0 0 1 1 1 0 DNA-binding domain TOM13 PF08219.6 ETO09237.1 - 0.14 11.9 0.2 0.16 11.7 0.1 1.1 1 0 0 1 1 1 0 Outer membrane protein TOM13 OATP PF03137.15 ETO09237.1 - 0.17 9.8 6.7 0.17 9.8 4.6 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family ATG27 PF09451.5 ETO09237.1 - 0.17 11.0 1.9 0.18 10.9 1.3 1.0 1 0 0 1 1 1 0 Autophagy-related protein 27 DUF4599 PF15371.1 ETO09237.1 - 0.44 10.6 4.7 0.51 10.4 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4599) DUF1764 PF08576.5 ETO09237.1 - 0.68 10.7 11.6 0.78 10.5 8.1 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Rot1 PF10681.4 ETO09237.1 - 0.7 9.1 2.6 0.73 9.1 1.8 1.0 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal FlgD PF03963.9 ETO09237.1 - 0.8 9.8 3.6 0.92 9.6 2.5 1.1 1 0 0 1 1 1 0 Flagellar hook capping protein - N-terminal region PEX11 PF05648.9 ETO09237.1 - 1 8.6 4.2 1 8.5 2.9 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) tRNA_synt_1c_R2 PF04557.10 ETO09237.1 - 1.5 9.5 14.7 1.8 9.3 10.2 1.1 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Peroxin-13_N PF04088.8 ETO09237.1 - 2.1 8.2 6.0 2.2 8.2 4.2 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Peptidase_S49_N PF08496.5 ETO09237.1 - 2.4 7.9 15.3 2.6 7.8 10.6 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Rtf2 PF04641.7 ETO09237.1 - 2.6 7.1 12.3 2.6 7.1 8.5 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Cucumo_2B PF03263.8 ETO09237.1 - 2.7 8.3 5.8 2.8 8.2 4.0 1.1 1 0 0 1 1 1 0 Cucumovirus protein 2B Vfa1 PF08432.5 ETO09237.1 - 3.4 7.6 14.3 3.6 7.5 9.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4652 PF15525.1 ETO09237.1 - 3.6 6.9 13.7 3.7 6.9 9.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) tRNA_lig_CPD PF08302.6 ETO09237.1 - 4.3 6.4 8.7 3.8 6.6 6.0 1.1 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain PcfJ PF14284.1 ETO09237.1 - 4.5 6.7 9.2 4.4 6.7 6.3 1.1 1 0 0 1 1 1 0 PcfJ-like protein GAGA_bind PF06217.7 ETO09237.1 - 4.8 7.0 12.0 5 7.0 8.4 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Cas_Csy4 PF09618.5 ETO09237.1 - 5.4 6.7 6.7 5.3 6.8 4.6 1.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) Di19_C PF14571.1 ETO09237.1 - 6.2 7.1 7.9 7.2 6.9 5.5 1.1 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal Eapp_C PF10238.4 ETO09237.1 - 7.2 6.5 10.7 7.8 6.4 7.4 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein O-ag_pol_Wzy PF14296.1 ETO09237.1 - 9.8 4.6 8.6 12 4.2 6.0 1.3 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy Ded_cyto PF06920.8 ETO09238.1 - 5.2e-16 58.4 0.8 1.5e-15 56.9 0.6 1.7 1 1 0 1 1 1 1 Dedicator of cytokinesis XisH PF08814.5 ETO09238.1 - 0.057 13.4 0.3 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 XisH protein WD40 PF00400.27 ETO09239.1 - 3.7e-44 147.0 15.8 2.7e-12 46.0 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO09239.1 - 1.1e-08 33.7 1.8 0.0039 15.3 0.1 3.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO09239.1 - 2.5e-06 27.7 2.8 2.5e-06 27.7 1.9 2.4 2 0 0 2 2 2 1 TRAF-type zinc finger CCDC144C PF14915.1 ETO09239.1 - 0.0015 17.5 8.2 0.0015 17.5 5.7 2.2 1 1 1 2 2 2 1 CCDC144C protein coiled-coil region DUF1053 PF06327.9 ETO09239.1 - 0.38 11.1 6.8 0.76 10.1 4.0 2.0 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1053) Jnk-SapK_ap_N PF09744.4 ETO09239.1 - 0.7 9.8 18.7 1.4 8.9 12.9 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Kinetocho_Slk19 PF12709.2 ETO09239.1 - 6.1 7.0 22.8 0.35 10.9 3.6 3.4 2 1 2 4 4 4 0 Central kinetochore-associated OmpH PF03938.9 ETO09239.1 - 9.2 6.1 16.1 19 5.1 11.2 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF912 PF06024.7 ETO09241.1 - 1.1 9.3 7.5 8.7 6.4 3.5 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FAD_binding_4 PF01565.18 ETO09242.1 - 0.015 14.7 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain DUF1691 PF07950.6 ETO09244.1 - 0.061 13.2 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1691) 14-3-3 PF00244.15 ETO09245.1 - 2.4e-18 66.1 1.6 3e-18 65.7 1.1 1.2 1 0 0 1 1 1 1 14-3-3 protein Copper-bind PF00127.15 ETO09246.1 - 0.034 14.3 0.1 0.061 13.5 0.1 1.4 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Cytokin-bind PF09265.5 ETO09246.1 - 0.037 13.1 0.4 0.059 12.5 0.3 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Cpn60_TCP1 PF00118.19 ETO09247.1 - 1.6e-10 40.2 0.0 1.8e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Tropomyosin_1 PF12718.2 ETO09248.1 - 4.7e-06 26.4 20.7 8.1e-05 22.4 8.4 2.1 1 1 1 2 2 2 2 Tropomyosin like HOOK PF05622.7 ETO09248.1 - 0.00012 20.0 10.9 0.00012 20.0 7.5 1.9 1 1 1 2 2 2 1 HOOK protein ADIP PF11559.3 ETO09248.1 - 0.00013 21.9 20.0 0.0024 17.7 7.1 2.1 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.16 ETO09248.1 - 0.0018 18.2 22.2 0.026 14.4 2.1 3.3 3 1 1 4 4 3 2 bZIP transcription factor ATG16 PF08614.6 ETO09248.1 - 0.0019 18.0 22.5 0.067 13.0 8.7 2.1 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Phlebovirus_NSM PF07246.6 ETO09248.1 - 0.0046 16.1 15.7 0.025 13.7 5.9 2.0 1 1 1 2 2 2 1 Phlebovirus nonstructural protein NS-M DUF3450 PF11932.3 ETO09248.1 - 0.0056 15.9 11.0 0.057 12.6 3.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) IncA PF04156.9 ETO09248.1 - 0.0067 16.0 19.0 0.13 11.8 13.3 2.1 1 1 0 1 1 1 1 IncA protein Filament PF00038.16 ETO09248.1 - 0.014 14.8 20.1 0.09 12.2 2.8 2.2 1 1 1 2 2 2 0 Intermediate filament protein Myosin_tail_1 PF01576.14 ETO09248.1 - 0.015 13.0 22.8 0.11 10.1 15.9 1.8 1 1 0 1 1 1 0 Myosin tail Microtub_assoc PF07989.6 ETO09248.1 - 0.027 14.2 1.0 0.027 14.2 0.7 3.3 2 1 1 3 3 3 0 Microtubule associated TPR_MLP1_2 PF07926.7 ETO09248.1 - 0.028 14.1 16.4 0.067 12.9 11.3 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Tropomyosin PF00261.15 ETO09248.1 - 0.031 13.3 20.5 1.3 8.0 14.3 2.7 1 1 0 1 1 1 0 Tropomyosin TMF_DNA_bd PF12329.3 ETO09248.1 - 0.031 14.0 25.7 0.03 14.1 5.4 2.8 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.3 ETO09248.1 - 0.037 13.7 17.6 0.061 13.0 7.6 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding TBPIP PF07106.8 ETO09248.1 - 0.046 13.2 16.2 0.067 12.7 5.2 2.4 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc7 PF08317.6 ETO09248.1 - 0.067 11.8 20.4 0.032 12.8 7.1 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Shugoshin_N PF07558.6 ETO09248.1 - 0.082 12.6 5.1 0.73 9.5 0.2 2.8 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region GAS PF13851.1 ETO09248.1 - 0.082 12.0 20.6 0.03 13.5 10.4 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding PEARLI-4 PF05278.7 ETO09248.1 - 0.087 12.1 15.1 0.18 11.1 2.7 2.0 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF972 PF06156.8 ETO09248.1 - 0.1 12.9 15.8 8.3 6.8 6.8 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Reo_sigmaC PF04582.7 ETO09248.1 - 0.11 11.6 3.6 0.21 10.7 2.5 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein bZIP_2 PF07716.10 ETO09248.1 - 0.13 12.1 0.8 0.13 12.1 0.5 4.0 4 2 1 5 5 3 0 Basic region leucine zipper Cauli_AT PF03233.8 ETO09248.1 - 0.13 11.9 11.7 0.97 9.1 1.8 2.3 1 1 1 2 2 2 0 Aphid transmission protein DUF2205 PF10224.4 ETO09248.1 - 0.15 11.6 13.8 2.3 7.8 4.5 2.6 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) Lebercilin PF15619.1 ETO09248.1 - 0.16 11.3 21.9 0.086 12.2 8.9 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Poty_PP PF08440.5 ETO09248.1 - 0.17 10.8 3.3 0.22 10.5 2.1 1.3 1 1 0 1 1 1 0 Potyviridae polyprotein Mod_r PF07200.8 ETO09248.1 - 0.2 11.5 14.6 1.3 8.9 4.1 2.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Prefoldin PF02996.12 ETO09248.1 - 0.22 11.2 13.1 0.51 10.0 0.9 3.1 2 1 1 3 3 3 0 Prefoldin subunit SlyX PF04102.7 ETO09248.1 - 0.25 11.7 16.2 0.54 10.6 2.7 3.8 1 1 3 4 4 3 0 SlyX SPAM PF02090.10 ETO09248.1 - 0.27 11.2 10.3 0.58 10.1 5.2 2.1 1 1 1 2 2 2 0 Salmonella surface presentation of antigen gene type M protein BLOC1_2 PF10046.4 ETO09248.1 - 0.28 11.3 11.0 0.1 12.7 4.3 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ERM PF00769.14 ETO09248.1 - 0.32 10.4 20.1 4.6 6.7 11.6 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family COG5 PF10392.4 ETO09248.1 - 0.35 10.8 11.1 3.3 7.6 3.9 2.2 1 1 1 2 2 2 0 Golgi transport complex subunit 5 CCDC155 PF14662.1 ETO09248.1 - 0.4 10.2 18.5 0.068 12.7 3.0 2.5 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 AAA_13 PF13166.1 ETO09248.1 - 0.47 8.8 14.6 0.89 7.9 10.1 1.5 1 1 0 1 1 1 0 AAA domain DUF1465 PF07323.7 ETO09248.1 - 0.5 9.9 7.7 0.44 10.1 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) DUF1202 PF06717.6 ETO09248.1 - 0.59 9.3 9.5 1 8.6 0.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1202) DUF904 PF06005.7 ETO09248.1 - 0.62 10.3 23.0 1 9.6 4.4 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF904) NPV_P10 PF05531.7 ETO09248.1 - 0.65 10.2 8.0 3.7 7.8 0.9 3.1 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1515 PF07439.6 ETO09248.1 - 0.69 9.7 11.4 1.1 9.1 1.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DUF2203 PF09969.4 ETO09248.1 - 0.7 10.1 6.4 4.1 7.6 4.4 2.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Nup54 PF13874.1 ETO09248.1 - 0.7 9.5 14.6 0.21 11.2 4.9 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Atg14 PF10186.4 ETO09248.1 - 0.76 8.6 22.8 0.44 9.4 6.6 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Jnk-SapK_ap_N PF09744.4 ETO09248.1 - 0.77 9.7 17.2 0.83 9.6 7.0 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Seryl_tRNA_N PF02403.17 ETO09248.1 - 0.81 9.7 18.4 0.26 11.3 5.4 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3972 PF13118.1 ETO09248.1 - 0.81 9.7 10.4 0.22 11.6 1.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3972) DUF2730 PF10805.3 ETO09248.1 - 0.83 9.4 9.1 1 9.1 2.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Syntaxin-6_N PF09177.6 ETO09248.1 - 0.87 10.0 12.5 0.28 11.5 3.3 2.8 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Fib_alpha PF08702.5 ETO09248.1 - 0.95 9.5 14.8 0.36 10.9 5.7 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.4 ETO09248.1 - 1 9.1 21.4 0.39 10.5 7.6 2.7 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LOH1CR12 PF10158.4 ETO09248.1 - 1.1 9.0 6.2 6.1 6.6 1.6 2.4 1 1 1 2 2 2 0 Tumour suppressor protein DUF4200 PF13863.1 ETO09248.1 - 1.1 9.2 20.2 0.73 9.7 6.7 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF444 PF04285.7 ETO09248.1 - 1.2 7.7 11.0 2.8 6.4 6.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF444) Phage_GP20 PF06810.6 ETO09248.1 - 1.2 8.5 18.4 0.99 8.8 4.1 2.5 1 1 1 2 2 2 0 Phage minor structural protein GP20 Macoilin PF09726.4 ETO09248.1 - 1.3 7.1 18.1 3.6 5.7 12.5 1.6 1 1 0 1 1 1 0 Transmembrane protein Spc24 PF08286.6 ETO09248.1 - 1.4 8.6 19.3 0.6 9.8 2.5 3.6 1 1 3 4 4 4 0 Spc24 subunit of Ndc80 DUF948 PF06103.6 ETO09248.1 - 1.4 8.7 7.7 7.4 6.5 0.4 3.0 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) KLRAQ PF10205.4 ETO09248.1 - 1.5 8.9 17.6 1.4 8.9 7.3 2.8 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF4140 PF13600.1 ETO09248.1 - 1.5 9.2 12.3 2.3 8.7 1.5 2.9 1 1 2 3 3 2 0 N-terminal domain of unknown function (DUF4140) DUF3552 PF12072.3 ETO09248.1 - 1.9 7.6 23.9 0.074 12.2 6.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Ax_dynein_light PF10211.4 ETO09248.1 - 2.1 8.1 19.4 0.042 13.6 4.8 3.0 1 1 2 3 3 3 0 Axonemal dynein light chain V_ATPase_I PF01496.14 ETO09248.1 - 2.2 6.0 15.3 0.061 11.1 3.9 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family TSC22 PF01166.13 ETO09248.1 - 2.6 8.0 10.7 6.3 6.8 0.2 3.6 1 1 2 3 3 3 0 TSC-22/dip/bun family Uds1 PF15456.1 ETO09248.1 - 2.8 7.9 17.8 4.9 7.1 5.5 2.4 1 1 1 2 2 2 0 Up-regulated During Septation DivIC PF04977.10 ETO09248.1 - 2.9 7.4 22.5 0.39 10.2 0.6 3.7 2 1 1 4 4 4 0 Septum formation initiator Prefoldin_2 PF01920.15 ETO09248.1 - 3 7.6 24.0 0.66 9.7 1.0 3.5 2 1 1 4 4 3 0 Prefoldin subunit MbeD_MobD PF04899.7 ETO09248.1 - 3.5 7.5 8.3 8.9 6.2 0.6 2.9 2 1 1 3 3 2 0 MbeD/MobD like FlxA PF14282.1 ETO09248.1 - 3.6 7.5 21.0 0.57 10.1 7.0 3.2 1 1 0 2 2 2 0 FlxA-like protein RTBV_P46 PF06216.6 ETO09248.1 - 3.6 6.3 6.3 7.5 5.2 0.7 2.1 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein DUF724 PF05266.9 ETO09248.1 - 3.9 7.0 20.1 2.5 7.6 7.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DivIVA PF05103.8 ETO09248.1 - 4.2 7.4 16.3 3 7.9 2.2 3.0 1 1 2 3 3 3 0 DivIVA protein APG6 PF04111.7 ETO09248.1 - 4.4 6.2 18.2 3 6.7 6.4 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Cortex-I_coil PF09304.5 ETO09248.1 - 4.5 7.3 18.7 0.12 12.4 4.7 2.8 1 1 1 2 2 1 0 Cortexillin I, coiled coil Snapin_Pallidin PF14712.1 ETO09248.1 - 6.4 7.1 16.3 0.17 12.1 0.4 2.8 3 1 0 3 3 2 0 Snapin/Pallidin Laminin_II PF06009.7 ETO09248.1 - 7 6.4 12.5 4.5 7.0 5.8 2.3 1 1 0 1 1 1 0 Laminin Domain II DUF641 PF04859.7 ETO09248.1 - 7.8 6.2 13.9 3.3 7.4 2.0 2.7 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) DUF4446 PF14584.1 ETO09248.1 - 8.4 6.2 12.3 1 9.1 2.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF2968 PF11180.3 ETO09248.1 - 8.4 5.7 15.0 7.2 5.9 4.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) CENP-F_leu_zip PF10473.4 ETO09249.1 - 0.00056 19.7 18.4 0.00056 19.7 12.8 6.5 2 2 3 5 5 5 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 ETO09249.1 - 0.0013 18.3 16.8 0.0013 18.3 11.6 6.0 1 1 5 6 6 5 2 IncA protein PspA_IM30 PF04012.7 ETO09249.1 - 0.0017 17.7 13.1 0.0017 17.7 9.1 5.3 2 2 1 4 4 3 1 PspA/IM30 family TPR_MLP1_2 PF07926.7 ETO09249.1 - 0.01 15.5 18.7 0.01 15.5 12.9 6.8 2 1 3 6 6 6 0 TPR/MLP1/MLP2-like protein Cep57_CLD_2 PF14197.1 ETO09249.1 - 0.011 15.7 10.5 0.011 15.7 7.3 9.9 3 3 6 9 9 7 0 Centrosome localisation domain of PPC89 DUF919 PF06034.6 ETO09249.1 - 0.015 14.8 1.0 0.015 14.8 0.7 8.7 6 2 1 7 7 6 0 Nucleopolyhedrovirus protein of unknown function (DUF919) ADIP PF11559.3 ETO09249.1 - 0.017 14.9 16.2 0.017 14.9 11.2 7.0 2 2 5 7 7 6 0 Afadin- and alpha -actinin-Binding DUF812 PF05667.6 ETO09249.1 - 0.58 8.6 112.3 0.22 10.0 18.9 4.8 2 1 3 5 5 5 0 Protein of unknown function (DUF812) DUF3584 PF12128.3 ETO09249.1 - 3.9 4.6 102.0 0.64 7.2 30.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 ETO09249.1 - 5.6 6.0 37.9 0.12 11.5 0.9 4.9 1 1 2 4 4 4 0 Reovirus sigma C capsid protein YvrJ PF12841.2 ETO09249.1 - 6.6 6.1 7.0 15 4.9 0.1 4.1 3 0 0 3 3 3 0 YvrJ protein family AAA_13 PF13166.1 ETO09249.1 - 9.8 4.4 97.9 1.3 7.4 19.5 3.1 1 1 1 3 3 3 0 AAA domain IBR PF01485.16 ETO09251.1 - 1e-09 38.0 15.1 1.4e-05 24.8 5.5 2.2 2 0 0 2 2 2 2 IBR domain Asparaginase_II PF06089.7 ETO09251.1 - 0.16 10.6 0.5 0.18 10.4 0.3 1.1 1 0 0 1 1 1 0 L-asparaginase II DZR PF12773.2 ETO09251.1 - 0.6 9.9 15.7 4.3 7.2 6.5 2.4 1 1 1 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 ETO09251.1 - 1.4 8.6 8.8 0.46 10.1 2.0 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zinc-ribbons_6 PF07191.7 ETO09251.1 - 1.5 8.6 12.5 6.7 6.5 4.1 2.3 2 0 0 2 2 2 0 zinc-ribbons TerY-C PF15616.1 ETO09251.1 - 8.2 6.3 13.4 6.3 6.7 4.0 2.9 1 1 1 2 2 2 0 TerY-C metal binding domain RGS PF00615.14 ETO09252.1 - 0.037 14.1 1.2 0.089 12.9 0.9 1.6 1 0 0 1 1 1 0 Regulator of G protein signaling domain PMC2NT PF08066.7 ETO09255.1 - 0.033 14.5 0.4 0.059 13.6 0.2 1.5 1 1 1 2 2 2 0 PMC2NT (NUC016) domain DUF1666 PF07891.7 ETO09255.1 - 0.086 12.2 0.7 0.092 12.1 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1666) DUF4363 PF14276.1 ETO09255.1 - 0.11 12.1 0.6 0.13 11.9 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) DAGK_prokar PF01219.14 ETO09255.1 - 0.12 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic diacylglycerol kinase zf-UBR PF02207.15 ETO09256.1 - 0.03 14.0 0.4 0.071 12.8 0.3 1.6 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) DUF3548 PF12068.3 ETO09256.1 - 0.47 9.7 6.3 0.082 12.1 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3548) Menin PF05053.8 ETO09256.1 - 4.7 5.2 15.1 9.3 4.2 10.4 1.4 1 0 0 1 1 1 0 Menin Vma12 PF11712.3 ETO09256.1 - 9.1 5.9 6.9 26 4.5 4.8 1.7 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase zf-RanBP PF00641.13 ETO09260.1 - 1.4e-05 24.0 5.7 2.7e-05 23.1 4.0 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Amino_oxidase PF01593.19 ETO09261.1 - 1.6e-25 90.0 0.1 2.2e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 ETO09261.1 - 1.1e-14 54.1 0.6 3.3e-14 52.6 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETO09261.1 - 1.5e-07 30.7 0.0 2.1e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 ETO09261.1 - 1.2e-06 28.5 0.7 4e-06 26.8 0.5 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETO09261.1 - 8.4e-06 26.1 0.4 3.1e-05 24.2 0.3 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETO09261.1 - 7.4e-05 21.3 0.2 7.4e-05 21.3 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 ETO09261.1 - 7.5e-05 21.7 0.4 0.00011 21.1 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 ETO09261.1 - 0.00025 20.0 0.4 0.00058 18.8 0.3 1.6 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 ETO09261.1 - 0.00032 19.8 0.1 0.00082 18.5 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 ETO09261.1 - 0.00047 19.3 0.0 0.00083 18.5 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 ETO09261.1 - 0.0005 20.1 0.4 0.0016 18.5 0.3 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETO09261.1 - 0.00091 18.3 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 ETO09261.1 - 0.0075 15.2 2.0 0.052 12.4 0.2 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_7 PF13241.1 ETO09261.1 - 0.03 14.5 0.0 0.072 13.3 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 ETO09261.1 - 0.072 12.2 0.3 0.15 11.1 0.2 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 ETO09261.1 - 0.076 12.6 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ETRAMP PF09716.5 ETO09261.1 - 0.084 12.8 0.2 0.084 12.8 0.1 4.3 4 1 0 4 4 2 0 Malarial early transcribed membrane protein (ETRAMP) TrkA_N PF02254.13 ETO09261.1 - 0.11 12.4 0.5 0.35 10.8 0.3 1.8 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.1 ETO09261.1 - 0.12 12.1 0.1 0.29 10.8 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding F-box-like PF12937.2 ETO09262.1 - 0.01 15.5 1.4 0.021 14.5 0.9 1.5 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 ETO09262.1 - 0.061 13.0 0.2 0.15 11.7 0.2 1.7 1 0 0 1 1 1 0 F-box domain DUF3513 PF12026.3 ETO09263.1 - 0.081 12.4 2.9 0.11 12.0 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) Cwf_Cwc_15 PF04889.7 ETO09263.1 - 0.11 12.2 13.3 0.14 11.8 9.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 ETO09263.1 - 0.16 9.9 7.5 0.19 9.7 5.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 ETO09263.1 - 0.29 9.8 13.0 0.36 9.4 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.7 ETO09263.1 - 0.43 9.8 11.7 0.55 9.4 8.1 1.1 1 0 0 1 1 1 0 SDA1 Autophagy_N PF03986.8 ETO09263.1 - 0.7 9.6 8.0 0.99 9.1 5.5 1.2 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain Macoilin PF09726.4 ETO09263.1 - 3 6.0 9.3 3.5 5.7 6.5 1.0 1 0 0 1 1 1 0 Transmembrane protein HGTP_anticodon2 PF12745.2 ETO09263.1 - 6.1 5.8 15.6 8.1 5.5 10.8 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs RdRP PF05183.7 ETO09265.1 - 2.1e-16 59.7 0.0 2.9e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase WWE PF02825.15 ETO09265.1 - 0.13 11.7 1.4 0.26 10.7 0.1 2.2 2 0 0 2 2 2 0 WWE domain RdRP PF05183.7 ETO09266.1 - 1.2e-16 60.6 0.5 1.5e-16 60.2 0.0 1.4 2 0 0 2 2 2 1 RNA dependent RNA polymerase RdRP PF05183.7 ETO09267.1 - 3.3e-24 85.5 0.3 4.1e-24 85.2 0.2 1.0 1 0 0 1 1 1 1 RNA dependent RNA polymerase UPF0118 PF01594.11 ETO09269.1 - 0.38 9.7 6.7 0.051 12.5 0.7 2.2 2 1 1 3 3 3 0 Domain of unknown function DUF20 DUF3782 PF12644.2 ETO09269.1 - 0.45 10.3 3.5 17 5.2 2.2 3.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) H-kinase_dim PF02895.9 ETO09269.1 - 3.2 8.1 10.8 0.38 11.1 0.1 3.7 3 1 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain DUF2678 PF10856.3 ETO09270.1 - 0.037 13.7 0.2 0.071 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) Phage_Gp23 PF10669.4 ETO09270.1 - 1.1 9.3 6.3 0.096 12.8 0.5 2.0 2 1 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DUF912 PF06024.7 ETO09270.1 - 1.8 8.6 3.7 1.3 9.1 0.8 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Virul_fac_BrkB PF03631.10 ETO09272.1 - 0.0078 15.5 0.1 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 Virulence factor BrkB APH PF01636.18 ETO09273.1 - 3.1e-17 63.1 0.0 6.1e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Acyl-CoA_dh_M PF02770.14 ETO09273.1 - 1.5e-09 37.1 0.0 2.8e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 ETO09273.1 - 1.9e-07 31.6 0.0 3.3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain EcKinase PF02958.15 ETO09273.1 - 7.9e-07 28.4 0.3 1.7e-06 27.4 0.2 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase Death PF00531.17 ETO09273.1 - 0.079 12.7 0.1 0.4 10.4 0.0 2.1 2 0 0 2 2 2 0 Death domain PPC PF04151.10 ETO09273.1 - 0.2 12.6 1.3 2.7 9.0 0.0 2.8 3 0 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain Acyl-CoA_dh_1 PF00441.19 ETO09274.1 - 1.6e-35 122.4 1.4 1.9e-35 122.1 0.9 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 ETO09274.1 - 3.2e-14 53.3 1.7 4e-14 52.9 1.1 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SNAP PF14938.1 ETO09274.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP HpaB_N PF11794.3 ETO09274.1 - 0.14 11.5 0.2 0.81 9.0 0.1 2.0 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal WD40 PF00400.27 ETO09275.1 - 7.1e-71 231.7 9.5 8.5e-14 50.8 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO09275.1 - 7.6e-13 48.6 1.0 3.9e-06 26.7 0.1 3.0 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO09275.1 - 2.6e-08 32.4 3.2 0.016 13.3 0.0 4.1 1 1 2 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO09275.1 - 1.5e-07 31.1 0.3 0.00011 21.8 0.0 2.7 1 1 1 2 2 2 2 PQQ-like domain Coatomer_WDAD PF04053.9 ETO09275.1 - 3.3e-07 29.4 1.4 0.008 15.0 0.3 2.5 1 1 1 2 2 2 2 Coatomer WD associated region Nucleoporin_N PF08801.6 ETO09275.1 - 1.7e-06 27.0 5.1 0.016 14.0 1.0 4.7 1 1 4 5 5 5 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO09275.1 - 8.1e-06 24.3 1.3 0.12 10.6 0.0 3.3 1 1 3 4 4 4 3 Cytochrome D1 heme domain DPPIV_N PF00930.16 ETO09275.1 - 0.00014 20.5 0.1 0.11 11.0 0.0 3.2 2 2 1 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.7 ETO09275.1 - 0.00015 21.3 7.3 6.6 6.5 0.1 6.0 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat DUF1652 PF07865.6 ETO09275.1 - 0.00058 19.4 0.0 2.7 7.6 0.0 3.9 3 2 2 5 5 5 1 Protein of unknown function (DUF1652) Hira PF07569.6 ETO09275.1 - 0.0017 17.5 0.3 3.4 6.8 0.0 3.7 1 1 3 4 4 4 1 TUP1-like enhancer of split PQQ PF01011.16 ETO09275.1 - 0.0019 17.6 0.1 16 5.2 0.0 4.7 6 0 0 6 6 6 0 PQQ enzyme repeat IKI3 PF04762.7 ETO09275.1 - 0.0024 15.7 0.1 0.83 7.3 0.0 2.2 1 1 0 2 2 2 2 IKI3 family Resistin PF06954.6 ETO09275.1 - 0.0051 17.0 0.1 12 6.2 0.2 3.2 2 1 1 3 3 3 0 Resistin Nup88 PF10168.4 ETO09275.1 - 0.012 13.5 0.3 0.79 7.4 0.0 2.8 1 1 1 3 3 3 0 Nuclear pore component B_lectin PF01453.19 ETO09275.1 - 0.015 15.1 0.6 0.63 9.9 0.1 2.4 2 0 0 2 2 2 0 D-mannose binding lectin CPSF_A PF03178.10 ETO09275.1 - 0.026 13.6 0.6 0.059 12.4 0.1 1.9 2 0 0 2 2 2 0 CPSF A subunit region DUF4221 PF13970.1 ETO09275.1 - 0.039 13.2 1.5 0.38 10.0 0.1 2.9 1 1 3 4 4 4 0 Domain of unknown function (DUF4221) Rav1p_C PF12234.3 ETO09275.1 - 0.17 10.0 2.0 4.7 5.2 0.0 2.6 1 1 2 3 3 3 0 RAVE protein 1 C terminal TH1 PF04858.8 ETO09276.1 - 0.00032 19.0 0.9 0.00032 19.0 0.6 2.3 1 1 2 3 3 3 2 TH1 protein TH1 PF04858.8 ETO09277.1 - 0.0048 15.1 0.7 0.16 10.0 0.0 2.1 2 0 0 2 2 2 2 TH1 protein Curto_V2 PF07325.6 ETO09277.1 - 0.023 14.3 0.6 0.061 12.9 0.4 1.7 1 0 0 1 1 1 0 Curtovirus V2 protein MSA-2c PF12238.3 ETO09277.1 - 0.097 12.3 0.5 4 7.0 0.1 2.2 2 0 0 2 2 2 0 Merozoite surface antigen 2c Sulfotransfer_2 PF03567.9 ETO09281.1 - 4e-05 23.4 0.7 0.00025 20.7 0.0 1.8 1 1 0 2 2 2 1 Sulfotransferase family DUF4306 PF14154.1 ETO09281.1 - 0.091 12.7 0.1 0.091 12.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4306) DSBA PF01323.15 ETO09282.1 - 2e-20 73.1 0.0 2.5e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 ETO09282.1 - 0.0046 16.9 0.1 0.015 15.3 0.0 1.9 2 1 0 2 2 2 1 Thioredoxin G3P_antiterm PF04309.7 ETO09282.1 - 0.062 12.3 0.2 0.095 11.7 0.1 1.2 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator MFS_1 PF07690.11 ETO09283.1 - 5.5e-13 48.3 0.6 1.1e-12 47.3 0.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 ETO09283.1 - 2.5e-06 27.0 2.7 2.5e-06 27.0 1.9 3.3 3 2 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_2 PF13347.1 ETO09283.1 - 0.01 14.2 9.2 0.01 14.2 1.0 2.5 2 1 0 2 2 2 0 MFS/sugar transport protein Abhydrolase_9_N PF15420.1 ETO09284.1 - 0.0024 17.6 0.6 0.0038 17.0 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta-hydrolase family N-terminus DUF3283 PF11686.3 ETO09284.1 - 1.4 8.7 5.1 0.17 11.6 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3283) Reticulon PF02453.12 ETO09284.1 - 6.6 6.3 17.0 1.8 8.1 7.5 3.0 1 1 0 2 2 2 0 Reticulon UCH_1 PF13423.1 ETO09285.1 - 6.1e-05 22.5 0.7 6.7e-05 22.4 0.5 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 ETO09285.1 - 0.0062 15.6 0.8 0.008 15.3 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase FYVE_2 PF02318.11 ETO09285.1 - 0.46 10.3 4.3 0.79 9.6 2.8 1.5 1 1 0 1 1 1 0 FYVE-type zinc finger Zn_Tnp_IS1595 PF12760.2 ETO09285.1 - 0.68 9.7 4.0 4.8 7.0 0.3 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 ETO09285.1 - 1.2 9.0 4.6 2 8.4 0.3 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Sgf11 PF08209.6 ETO09285.1 - 7.2 6.0 7.1 8 5.8 1.1 2.5 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) PA14 PF07691.7 ETO09286.1 - 0.32 10.6 8.0 0.54 9.8 4.2 2.3 2 1 0 2 2 2 0 PA14 domain Med15 PF09606.5 ETO09287.1 - 0.037 12.2 12.5 0.045 11.9 8.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DnaJ PF00226.26 ETO09290.1 - 6.7e-16 57.7 2.7 1.8e-15 56.3 1.9 1.8 1 0 0 1 1 1 1 DnaJ domain Bac_globin PF01152.16 ETO09290.1 - 0.00043 20.2 0.3 0.0012 18.8 0.0 1.9 2 0 0 2 2 2 1 Bacterial-like globin Ank PF00023.25 ETO09291.1 - 4.5e-24 83.0 7.5 4.1e-09 35.7 0.5 4.1 4 1 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 ETO09291.1 - 4.3e-23 81.4 6.6 1.1e-11 44.9 1.6 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO09291.1 - 1.6e-16 59.8 4.8 3.2e-10 39.9 0.6 3.4 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO09291.1 - 5.4e-16 58.6 7.0 2.7e-06 27.7 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO09291.1 - 2.4e-13 48.9 5.1 0.00019 21.3 0.2 4.1 3 1 0 3 3 3 3 Ankyrin repeat WD40 PF00400.27 ETO09292.1 - 9.3e-63 206.0 20.1 2.4e-11 43.0 0.4 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO09292.1 - 1.8e-13 49.4 6.6 0.0024 16.0 0.2 5.4 1 1 5 6 6 6 5 Nucleoporin Nup120/160 WD40 PF00400.27 ETO09293.1 - 1e-54 180.5 19.4 9e-12 44.3 0.8 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO09293.1 - 1.2e-10 40.1 8.9 0.00017 19.8 0.6 5.5 1 1 2 4 4 4 4 Nucleoporin Nup120/160 AAA_14 PF13173.1 ETO09293.1 - 0.055 13.3 2.2 0.12 12.3 0.3 2.3 2 1 1 3 3 3 0 AAA domain Guanylate_cyc PF00211.15 ETO09294.1 - 2.2e-06 27.1 0.0 2.9e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF4451 PF14616.1 ETO09295.1 - 0.022 14.5 1.1 0.03 14.0 0.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4451) WD40 PF00400.27 ETO09296.1 - 0.00019 21.1 1.3 0.00038 20.2 0.4 1.8 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF2603 PF10788.4 ETO09296.1 - 0.021 14.5 0.2 0.028 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2603) CAAP1 PF15335.1 ETO09296.1 - 0.053 13.7 0.7 0.1 12.7 0.5 1.4 1 0 0 1 1 1 0 Caspase activity and apoptosis inhibitor 1 TA0956 PF11513.3 ETO09296.1 - 0.18 11.8 2.2 0.21 11.6 1.1 1.6 1 1 0 1 1 1 0 Thermoplasma acidophilum protein TA0956 DUF4421 PF14391.1 ETO09297.1 - 0.0054 15.9 1.9 0.0068 15.6 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4421) Glycolytic PF00274.14 ETO09297.1 - 0.018 13.4 0.1 0.064 11.6 0.0 1.8 1 1 1 2 2 2 0 Fructose-bisphosphate aldolase class-I PFK PF00365.15 ETO09298.1 - 1.6e-25 89.6 1.3 2.1e-25 89.2 0.9 1.1 1 0 0 1 1 1 1 Phosphofructokinase RelA_SpoT PF04607.12 ETO09302.1 - 0.0015 18.5 0.3 0.0015 18.5 0.2 2.6 3 0 0 3 3 3 1 Region found in RelA / SpoT proteins WD40 PF00400.27 ETO09303.1 - 1.8e-143 461.8 41.0 3.8e-11 42.4 0.1 15.3 15 0 0 15 15 15 15 WD domain, G-beta repeat PD40 PF07676.7 ETO09303.1 - 3.8e-11 42.3 30.4 0.91 9.2 0.0 11.6 12 0 0 12 12 12 5 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 ETO09303.1 - 1.2e-09 37.6 0.7 0.25 10.3 0.0 6.1 2 1 2 5 5 5 3 Protein of unknown function (DUF1258) Cytochrom_D1 PF02239.11 ETO09303.1 - 3.9e-07 28.6 4.3 1.5 7.0 0.0 5.5 2 1 5 8 8 8 4 Cytochrome D1 heme domain Str_synth PF03088.11 ETO09303.1 - 9.4e-07 28.7 0.3 1.8 8.6 0.0 7.6 9 0 0 9 9 9 1 Strictosidine synthase Pentapeptide_4 PF13599.1 ETO09303.1 - 9.7e-06 25.3 0.1 3e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETO09303.1 - 1.4e-05 24.1 1.0 4.8e-05 22.4 0.7 2.0 1 1 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 ETO09303.1 - 0.00021 21.1 0.6 0.00073 19.3 0.1 2.3 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) DUF3475 PF11961.3 ETO09303.1 - 0.014 15.2 0.2 24 4.8 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF3475) Resistin PF06954.6 ETO09303.1 - 0.14 12.4 0.1 1.4e+02 2.8 0.0 4.9 5 0 0 5 5 5 0 Resistin LRR_4 PF12799.2 ETO09304.1 - 1.5e-05 24.4 63.3 0.00087 18.8 0.6 10.6 4 1 8 12 12 12 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO09304.1 - 5.2e-05 22.9 8.6 0.00018 21.1 1.9 8.0 5 2 2 7 7 7 4 Leucine rich repeat LRR_1 PF00560.28 ETO09304.1 - 0.00017 21.1 44.5 1 9.6 0.1 12.3 12 0 0 12 12 12 4 Leucine Rich Repeat Pkinase PF00069.20 ETO09305.1 - 1.8e-24 86.3 0.6 2e-17 63.1 0.0 2.9 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO09305.1 - 8.9e-14 51.1 0.1 3.2e-11 42.7 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 ETO09305.1 - 0.015 14.4 0.1 0.039 13.0 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family PBP1_TM PF14812.1 ETO09305.1 - 0.017 15.4 0.3 0.077 13.3 0.2 2.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ofd1_CTDD PF10637.4 ETO09305.1 - 4.2 6.4 11.0 1.3 8.0 5.1 1.8 1 1 1 2 2 2 0 Oxoglutarate and iron-dependent oxygenase degradation C-term Arm PF00514.18 ETO09307.1 - 8e-11 41.3 0.0 0.00035 20.2 0.0 3.9 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 ETO09307.1 - 0.00014 22.2 0.0 0.47 11.0 0.0 2.6 2 0 0 2 2 2 2 HEAT-like repeat HEAT_2 PF13646.1 ETO09307.1 - 0.0011 19.1 0.0 0.21 11.8 0.0 2.3 1 1 1 2 2 2 2 HEAT repeats Adaptin_N PF01602.15 ETO09307.1 - 0.072 11.4 0.0 1.1 7.5 0.0 1.9 1 1 1 2 2 2 0 Adaptin N terminal region FYVE PF01363.16 ETO09308.1 - 5.8e-07 29.3 8.6 5.8e-07 29.3 5.9 4.9 2 2 1 3 3 3 1 FYVE zinc finger IBR PF01485.16 ETO09308.1 - 0.00069 19.4 57.6 0.0076 16.1 6.5 6.3 4 3 1 5 5 5 3 IBR domain zf-C3HC4 PF00097.20 ETO09308.1 - 0.028 14.0 2.6 0.028 14.0 1.8 6.7 4 3 2 6 6 6 0 Zinc finger, C3HC4 type (RING finger) ELO PF01151.13 ETO09309.1 - 5e-21 75.1 0.8 5.9e-21 74.8 0.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family AgrB PF04647.10 ETO09309.1 - 0.0022 17.0 0.1 0.0058 15.7 0.1 1.6 1 1 0 1 1 1 1 Accessory gene regulator B IBB PF01749.15 ETO09311.1 - 4.2e-06 26.8 2.6 8.1e-06 25.9 1.8 1.4 1 0 0 1 1 1 1 Importin beta binding domain DUF3552 PF12072.3 ETO09311.1 - 0.32 10.1 4.5 0.53 9.4 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) TSSC4 PF15264.1 ETO09312.1 - 0.012 16.1 1.4 0.015 15.7 0.1 1.7 2 0 0 2 2 2 0 Tumour suppressing sub-chromosomal transferable candidate 4 ABC2_membrane_4 PF12730.2 ETO09312.1 - 0.043 12.9 4.5 0.092 11.8 1.0 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein Daxx PF03344.10 ETO09313.1 - 0.15 10.5 24.8 0.19 10.1 17.2 1.1 1 0 0 1 1 1 0 Daxx Family ECH PF00378.15 ETO09314.1 - 4.7e-35 120.8 0.2 1.9e-15 56.6 0.0 3.0 3 0 0 3 3 3 3 Enoyl-CoA hydratase/isomerase family SSXT PF05030.7 ETO09315.1 - 0.0012 18.4 0.3 0.005 16.3 0.0 2.0 2 0 0 2 2 2 1 SSXT protein (N-terminal region) DZR PF12773.2 ETO09315.1 - 0.05 13.4 0.5 0.093 12.5 0.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-C3HC4_3 PF13920.1 ETO09315.1 - 0.18 11.5 1.1 0.33 10.6 0.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PQQ_3 PF13570.1 ETO09316.1 - 0.043 14.1 0.8 0.84 10.0 0.0 2.5 2 0 0 2 2 2 0 PQQ-like domain TPR_11 PF13414.1 ETO09318.1 - 1.2e-10 40.8 0.5 3.6e-09 36.1 0.0 2.8 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 ETO09318.1 - 1.4e-07 30.8 0.7 0.0019 17.7 0.2 3.9 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO09318.1 - 7.2e-07 28.6 0.9 0.00083 19.0 0.3 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO09318.1 - 3.6e-05 23.6 0.1 0.039 14.1 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO09318.1 - 0.0069 17.0 0.0 0.027 15.1 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO09318.1 - 0.011 15.4 0.3 2.7 7.9 0.1 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO09318.1 - 0.07 13.6 0.0 2.2 8.9 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETO09318.1 - 0.13 12.2 2.7 0.97 9.4 0.5 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat Senescence_reg PF04520.8 ETO09318.1 - 4.6 7.7 7.0 19 5.7 4.8 1.9 1 1 0 1 1 1 0 Senescence regulator Metallophos PF00149.23 ETO09319.1 - 1.2e-08 34.6 6.5 4e-08 32.8 4.5 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 ETO09319.1 - 1.6e-08 34.5 0.2 1.4e-07 31.5 0.1 2.6 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.2 ETO09319.1 - 0.00074 19.3 0.0 0.0015 18.4 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PhoD PF09423.5 ETO09319.1 - 0.018 13.6 0.0 0.039 12.5 0.0 1.5 2 0 0 2 2 2 0 PhoD-like phosphatase Ribosomal_S26e PF01283.14 ETO09320.1 - 2.9e-14 53.2 8.5 2.9e-14 53.2 5.9 3.3 2 2 1 3 3 3 1 Ribosomal protein S26e Agro_virD5 PF04730.7 ETO09320.1 - 0.011 13.7 0.0 0.011 13.7 0.0 1.4 2 0 0 2 2 2 0 Agrobacterium VirD5 protein Cytochrom_B_N PF00033.14 ETO09320.1 - 0.043 13.1 0.5 0.21 10.9 0.0 1.9 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB DUF3043 PF11241.3 ETO09320.1 - 0.2 11.2 0.0 0.2 11.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) IncFII_repA PF02387.10 ETO09320.1 - 0.38 9.8 14.1 0.31 10.1 1.0 2.3 2 0 0 2 2 2 0 IncFII RepA protein family MutS_III PF05192.13 ETO09322.1 - 3.2e-19 69.5 7.7 3.2e-19 69.5 5.4 2.6 2 2 0 2 2 2 1 MutS domain III MutS_II PF05188.12 ETO09322.1 - 1.4e-05 25.2 0.2 0.00031 20.8 0.0 2.9 3 0 0 3 3 3 1 MutS domain II Mucin PF01456.12 ETO09322.1 - 0.014 15.1 12.4 0.044 13.5 7.2 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3439 PF11921.3 ETO09322.1 - 0.073 12.8 7.2 0.2 11.3 5.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) RP-C_C PF11800.3 ETO09322.1 - 0.15 11.7 11.3 0.69 9.5 2.0 2.5 2 0 0 2 2 2 0 Replication protein C C-terminal region CobT PF06213.7 ETO09322.1 - 0.62 9.1 8.2 1.4 7.9 0.4 2.6 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT NRDE-2 PF08424.5 ETO09322.1 - 7.8 5.2 13.8 1.1 8.1 4.7 2.3 2 0 0 2 2 2 0 NRDE-2, necessary for RNA interference Kelch_6 PF13964.1 ETO09323.1 - 7.1e-09 35.4 0.7 2.7e-06 27.3 0.1 2.2 1 1 0 2 2 2 2 Kelch motif Kelch_1 PF01344.20 ETO09323.1 - 2.6e-08 33.2 1.0 1.2e-06 27.9 0.2 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.1 ETO09323.1 - 1.7e-06 27.7 0.0 0.019 14.6 0.0 2.3 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO09323.1 - 0.00023 20.7 0.8 0.027 14.2 0.6 2.6 2 1 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO09323.1 - 0.015 15.4 0.0 0.1 12.8 0.0 2.1 2 0 0 2 2 2 0 Galactose oxidase, central domain SEO_C PF14577.1 ETO09323.1 - 0.052 12.9 0.2 0.093 12.0 0.1 1.5 1 1 0 1 1 1 0 Sieve element occlusion C-terminus DUF1467 PF07330.7 ETO09324.1 - 0.082 12.7 0.9 0.65 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1467) DUF1980 PF09323.5 ETO09324.1 - 0.32 10.7 4.3 3.2 7.4 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DnaJ PF00226.26 ETO09325.1 - 2.1e-05 24.1 5.1 2.1e-05 24.1 3.5 1.7 2 0 0 2 2 2 1 DnaJ domain ABC2_membrane_5 PF13346.1 ETO09325.1 - 0.002 17.4 0.3 0.0024 17.1 0.2 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF1980 PF09323.5 ETO09325.1 - 0.0034 17.1 0.7 0.0034 17.1 0.5 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF1980) Phage_Gp23 PF10669.4 ETO09325.1 - 0.022 14.8 1.2 0.036 14.1 0.0 1.9 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) RSN1_TM PF13967.1 ETO09325.1 - 0.035 13.6 0.4 2.2 7.8 0.0 2.3 2 1 0 2 2 2 0 Late exocytosis, associated with Golgi transport VIT1 PF01988.14 ETO09325.1 - 0.14 11.6 0.1 0.23 10.9 0.0 1.5 1 1 1 2 2 2 0 VIT family DUF1129 PF06570.6 ETO09325.1 - 3.7 6.8 6.1 6.9 5.9 2.6 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) DUF4181 PF13789.1 ETO09325.1 - 5.4 6.9 8.8 0.045 13.6 0.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) CTDII PF01556.13 ETO09326.1 - 1.1e-18 66.8 0.1 9.2e-15 54.3 0.0 2.2 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 ETO09326.1 - 0.061 13.3 0.1 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 DnaJ central domain Herpes_U26 PF07402.6 ETO09326.1 - 0.17 11.1 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Human herpesvirus U26 protein DSHCT PF08148.7 ETO09327.1 - 1.6e-53 180.6 0.5 4.6e-53 179.1 0.4 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.1 ETO09327.1 - 4.3e-48 163.8 10.8 1.5e-46 158.7 3.1 2.2 2 0 0 2 2 2 2 rRNA-processing arch domain Helicase_C PF00271.26 ETO09327.1 - 1.1e-07 31.6 0.0 4.2e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1488 PF07369.6 ETO09327.1 - 0.042 13.6 0.2 0.31 10.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) DUF1664 PF07889.7 ETO09327.1 - 0.26 11.1 3.1 8.6 6.1 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4163 PF13739.1 ETO09327.1 - 2.2 9.0 4.7 9.2 7.1 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4163) DUF1336 PF07059.7 ETO09328.1 - 4e-05 23.1 0.2 6.1e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) zf-RanBP PF00641.13 ETO09329.1 - 0.00033 19.6 6.2 0.00071 18.6 4.3 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF1749 PF08538.5 ETO09330.1 - 0.028 13.3 0.0 0.032 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Ank_4 PF13637.1 ETO09330.1 - 0.076 13.5 0.0 0.72 10.4 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) C2 PF00168.25 ETO09331.1 - 1.6e-08 34.2 0.0 5.6e-06 26.1 0.0 2.5 2 0 0 2 2 2 2 C2 domain RasGEF PF00617.14 ETO09332.1 - 7.2e-36 123.6 5.1 7.2e-36 123.6 3.5 1.4 2 0 0 2 2 2 1 RasGEF domain Orn_Arg_deC_N PF02784.11 ETO09332.1 - 0.19 10.9 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain RasGEF_N PF00618.15 ETO09333.1 - 1e-12 48.0 1.6 1.6e-12 47.4 0.1 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif RasGEF PF00617.14 ETO09333.1 - 8.6e-05 22.3 0.1 0.00031 20.5 0.0 2.0 2 0 0 2 2 2 1 RasGEF domain SET PF00856.23 ETO09335.1 - 0.13 12.5 3.3 1.5 9.0 0.0 3.3 2 2 0 2 2 2 0 SET domain CDC45 PF02724.9 ETO09337.1 - 0.012 13.6 8.3 0.017 13.2 5.8 1.2 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.10 ETO09337.1 - 0.11 11.0 11.7 0.17 10.4 8.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Daxx PF03344.10 ETO09337.1 - 2.2 6.6 23.5 3.3 6.0 16.3 1.2 1 0 0 1 1 1 0 Daxx Family Pox_Ag35 PF03286.9 ETO09337.1 - 2.5 7.5 16.8 7.3 6.0 11.6 1.8 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.7 ETO09337.1 - 2.7 5.7 24.9 3.9 5.2 17.3 1.1 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.8 ETO09337.1 - 4.8 5.8 19.6 0.41 9.3 10.4 1.5 2 0 0 2 2 2 0 Paf1 DUF2457 PF10446.4 ETO09337.1 - 7.6 5.1 27.5 12 4.5 19.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CENP-T PF15511.1 ETO09337.1 - 8.7 5.4 13.1 13 4.8 9.1 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Leu_Phe_trans PF03588.9 ETO09339.1 - 1e-12 47.5 0.0 3.4e-06 26.2 0.0 2.2 2 0 0 2 2 2 2 Leucyl/phenylalanyl-tRNA protein transferase TFIIA PF03153.8 ETO09340.1 - 0.042 13.7 16.9 0.051 13.4 11.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dicty_REP PF05086.7 ETO09340.1 - 0.064 11.0 24.1 0.082 10.6 16.7 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Macoilin PF09726.4 ETO09340.1 - 4.7 5.3 23.0 6.2 4.9 15.9 1.2 1 0 0 1 1 1 0 Transmembrane protein WD40 PF00400.27 ETO09341.1 - 1.2e-22 78.8 8.6 3.3e-09 36.2 0.0 3.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO09341.1 - 0.00015 20.0 1.4 0.0072 14.5 0.4 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PqiA PF04403.8 ETO09343.1 - 0.0074 15.8 2.5 0.0074 15.8 1.8 2.0 2 0 0 2 2 2 1 Paraquat-inducible protein A DUF4131 PF13567.1 ETO09343.1 - 0.02 14.3 0.0 0.054 12.9 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) NicO PF03824.11 ETO09343.1 - 0.023 13.9 0.2 0.052 12.8 0.1 1.6 1 1 0 1 1 1 0 High-affinity nickel-transport protein Ras PF00071.17 ETO09344.1 - 3.9e-18 65.3 0.0 6.5e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO09344.1 - 8.5e-08 32.7 0.2 1.8e-07 31.6 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein DUF2969 PF11184.3 ETO09344.1 - 0.05 13.6 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2969) GAS PF13851.1 ETO09345.1 - 0.0034 16.6 11.5 0.0034 16.6 8.0 5.1 3 1 2 6 6 6 3 Growth-arrest specific micro-tubule binding FlaC_arch PF05377.6 ETO09345.1 - 1.3 9.0 27.5 0.16 11.9 0.2 4.8 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) Mod_r PF07200.8 ETO09345.1 - 1.4 8.7 56.9 0.046 13.6 7.3 6.0 5 2 0 5 5 5 0 Modifier of rudimentary (Mod(r)) protein ApoO PF09769.4 ETO09345.1 - 6.7 6.4 7.7 3.5 7.3 1.4 3.1 3 0 0 3 3 3 0 Apolipoprotein O DUF2693 PF10902.3 ETO09345.1 - 9.9 6.1 8.6 29 4.6 0.0 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2693) TFIIF_alpha PF05793.7 ETO09346.1 - 2.9e-06 25.9 12.5 2.9e-06 25.9 8.7 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Daxx PF03344.10 ETO09346.1 - 3.9e-05 22.3 21.1 4.2e-05 22.2 14.6 1.1 1 0 0 1 1 1 1 Daxx Family Ycf1 PF05758.7 ETO09346.1 - 0.00087 17.1 11.8 0.00087 17.1 8.2 1.1 1 0 0 1 1 1 1 Ycf1 CDC45 PF02724.9 ETO09346.1 - 0.0061 14.6 15.1 0.0065 14.5 10.5 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF572 PF04502.8 ETO09346.1 - 0.064 12.4 17.9 0.1 11.8 12.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) SAPS PF04499.10 ETO09346.1 - 0.064 11.8 6.8 0.056 12.0 4.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MIP-T3 PF10243.4 ETO09346.1 - 0.12 10.8 22.9 0.15 10.4 15.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1776 PF08643.5 ETO09346.1 - 0.2 10.7 0.9 0.43 9.6 0.3 1.7 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) CTNNB1_binding PF08347.6 ETO09346.1 - 0.29 11.3 15.1 0.37 11.0 10.5 1.1 1 0 0 1 1 1 0 N-terminal CTNNB1 binding Tim54 PF11711.3 ETO09346.1 - 0.37 9.3 11.8 0.45 9.0 8.2 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Lin-8 PF03353.10 ETO09346.1 - 0.38 9.9 14.5 0.48 9.6 10.0 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Mem_trans PF03547.13 ETO09346.1 - 0.65 8.2 3.6 0.81 7.9 2.5 1.2 1 0 0 1 1 1 0 Membrane transport protein Nop14 PF04147.7 ETO09346.1 - 1.2 6.9 34.5 1.5 6.6 23.9 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 ETO09346.1 - 1.6 7.6 26.8 1.8 7.5 18.6 1.2 1 0 0 1 1 1 0 BUD22 Peptidase_S64 PF08192.6 ETO09346.1 - 4.2 5.5 10.1 4.9 5.3 7.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF605 PF04652.11 ETO09346.1 - 4.3 6.6 21.1 5.1 6.3 14.7 1.1 1 0 0 1 1 1 0 Vta1 like DUF3816 PF12822.2 ETO09347.1 - 0.045 13.6 3.0 0.63 9.9 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3816) Neur_chan_memb PF02932.11 ETO09347.1 - 4.5 7.0 12.7 3.5 7.4 6.7 2.3 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF843 PF05814.6 ETO09349.1 - 2 8.2 4.6 16 5.3 3.6 2.1 1 1 1 2 2 2 0 Baculovirus protein of unknown function (DUF843) DUF3488 PF11992.3 ETO09350.1 - 0.032 12.8 3.3 0.038 12.6 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) CCSMST1 PF15013.1 ETO09350.1 - 0.049 13.5 0.8 0.52 10.2 0.2 2.1 2 0 0 2 2 2 0 CCSMST1 family NfeD PF01957.13 ETO09350.1 - 0.051 13.7 0.3 0.051 13.7 0.2 1.8 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding SirB PF04247.7 ETO09350.1 - 0.077 12.7 3.2 0.11 12.2 1.5 1.8 1 1 1 2 2 2 0 Invasion gene expression up-regulator, SirB UPF0697 PF15117.1 ETO09350.1 - 0.093 12.5 0.4 0.15 11.8 0.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0697 DUF4131 PF13567.1 ETO09350.1 - 0.3 10.4 2.3 0.28 10.5 0.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF4181 PF13789.1 ETO09350.1 - 0.6 10.0 7.6 0.58 10.0 4.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4181) DUF202 PF02656.10 ETO09350.1 - 0.8 9.9 3.7 4 7.7 2.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF843 PF05814.6 ETO09350.1 - 0.92 9.3 7.0 0.2 11.4 1.4 2.0 1 1 1 2 2 2 0 Baculovirus protein of unknown function (DUF843) NB PF04159.8 ETO09350.1 - 0.94 9.2 8.5 1.1 9.0 0.6 2.2 1 1 1 2 2 2 0 NB glycoprotein DUF4064 PF13273.1 ETO09350.1 - 1 9.5 6.4 0.16 12.0 1.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) UPF0104 PF03706.8 ETO09350.1 - 2.8 7.1 6.6 5.7 6.1 4.7 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0104) zf-DHHC PF01529.15 ETO09350.1 - 2.9 7.2 6.4 4.2 6.7 4.4 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase P12 PF12669.2 ETO09350.1 - 3.6 7.8 5.2 9.6 6.4 0.3 2.5 2 0 0 2 2 2 0 Virus attachment protein p12 family DUF1430 PF07242.6 ETO09350.1 - 6.4 6.9 10.3 1.2 9.2 2.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1430) DUF2207 PF09972.4 ETO09350.1 - 7.3 5.0 7.7 8.2 4.8 2.9 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF3384 PF11864.3 ETO09351.1 - 0.0024 16.4 2.8 0.0029 16.1 2.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) DUF4652 PF15525.1 ETO09351.1 - 0.0058 16.0 1.2 0.0058 16.0 0.9 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4652) Secretin_N_2 PF07655.8 ETO09351.1 - 4.2 7.8 13.4 1.2 9.6 6.9 1.8 2 0 0 2 2 2 0 Secretin N-terminal domain DUF3529 PF12046.3 ETO09352.1 - 0.19 10.7 1.6 0.23 10.4 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3529) DUF1131 PF06572.7 ETO09352.1 - 0.28 10.6 1.8 0.31 10.4 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1131) Auxin_inducible PF02519.9 ETO09352.1 - 0.9 9.6 4.7 0.43 10.6 0.2 2.1 2 0 0 2 2 2 0 Auxin responsive protein SLX9 PF15341.1 ETO09352.1 - 1.6 9.1 15.0 2.5 8.5 10.4 1.2 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 RCR PF12273.3 ETO09352.1 - 2.1 8.9 4.7 3.3 8.2 3.3 1.4 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Peptidase_C14 PF00656.17 ETO09353.1 - 6.3e-13 48.9 1.4 1.7e-12 47.6 0.1 2.0 1 1 0 2 2 2 1 Caspase domain Fcf1 PF04900.7 ETO09353.1 - 0.29 11.2 5.0 3.9 7.6 0.0 3.7 4 1 1 5 5 5 0 Fcf1 2-Hacid_dh PF00389.25 ETO09354.1 - 0.012 15.1 0.1 0.023 14.1 0.0 1.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Cgr1 PF03879.9 ETO09354.1 - 0.13 12.4 2.2 0.14 12.3 0.2 1.9 2 0 0 2 2 2 0 Cgr1 family ArfGap PF01412.13 ETO09355.1 - 2.5e-31 107.8 1.7 7.4e-31 106.3 1.2 1.8 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.24 ETO09355.1 - 2.5e-13 50.1 0.9 2.5e-13 50.1 0.6 2.4 2 1 0 2 2 2 1 PH domain Ank_2 PF12796.2 ETO09355.1 - 1e-07 32.1 0.1 3.7e-07 30.4 0.1 1.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) PH_8 PF15409.1 ETO09355.1 - 3.8e-07 30.0 1.0 3.8e-07 30.0 0.7 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain Ank_5 PF13857.1 ETO09355.1 - 1.6e-06 28.1 0.0 4e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 ETO09355.1 - 2.4e-06 27.0 0.2 1.7e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat PH_11 PF15413.1 ETO09355.1 - 2.9e-06 27.4 6.0 3.9e-06 27.0 2.1 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain Ank_3 PF13606.1 ETO09355.1 - 0.00064 19.7 0.0 0.0025 17.8 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.1 ETO09355.1 - 0.071 13.6 0.0 0.23 12.0 0.0 2.0 1 1 0 1 1 1 0 Ankyrin repeats (many copies) PH_9 PF15410.1 ETO09355.1 - 0.09 12.9 2.1 0.61 10.2 0.3 3.0 2 1 0 2 2 2 0 Pleckstrin homology domain DENN PF02141.16 ETO09356.1 - 1.7e-17 63.7 0.6 5.2e-11 42.6 0.1 2.2 2 0 0 2 2 2 2 DENN (AEX-3) domain PDGF PF00341.12 ETO09357.1 - 0.049 13.7 1.0 0.068 13.2 0.1 1.7 2 0 0 2 2 2 0 PDGF/VEGF domain Ank_2 PF12796.2 ETO09360.1 - 0.0012 19.1 0.1 0.63 10.4 0.0 2.5 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO09360.1 - 0.0024 17.9 1.6 11 6.5 0.1 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.25 ETO09360.1 - 0.015 15.0 0.8 4.1 7.3 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeat Ank_4 PF13637.1 ETO09360.1 - 0.022 15.2 0.7 2.4 8.7 0.0 2.9 2 1 1 3 3 3 0 Ankyrin repeats (many copies) SOBP PF15279.1 ETO09360.1 - 0.023 15.0 7.0 0.035 14.4 4.9 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein PA26 PF04636.8 ETO09360.1 - 0.029 13.0 8.8 0.055 12.1 6.1 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) YlzJ PF14035.1 ETO09360.1 - 3.7 7.6 5.6 1.5 8.8 0.5 2.7 2 0 0 2 2 2 0 YlzJ-like protein DDHD PF02862.12 ETO09360.1 - 8.7 6.0 22.1 0.89 9.3 9.9 2.2 1 1 1 2 2 2 0 DDHD domain Macoilin PF09726.4 ETO09361.1 - 0.29 9.3 14.4 0.36 9.0 10.0 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF2632 PF10943.3 ETO09361.1 - 0.53 9.7 2.6 0.98 8.8 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2632) Ipi1_N PF12333.3 ETO09361.1 - 1.1 9.2 7.9 1.8 8.5 5.0 1.6 1 1 1 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation Apt1 PF10351.4 ETO09361.1 - 7.7 5.2 9.3 11 4.8 6.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain zf-C2H2 PF00096.21 ETO09362.1 - 1.2e-05 25.2 8.8 0.0041 17.3 0.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETO09362.1 - 1.5e-05 24.9 11.2 1.9e-05 24.7 1.8 2.6 2 0 0 2 2 2 1 Zinc-finger double domain zf-Di19 PF05605.7 ETO09362.1 - 0.00025 21.1 2.9 0.00049 20.1 2.0 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 ETO09362.1 - 0.00059 19.9 9.6 0.012 15.9 0.1 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 ETO09362.1 - 0.0039 17.3 4.4 0.52 10.5 0.0 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 ETO09362.1 - 0.059 13.5 5.9 0.67 10.1 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Methyltransf_12 PF08242.7 ETO09362.1 - 1.4 9.4 6.0 18 5.8 0.1 2.8 2 0 0 2 2 2 0 Methyltransferase domain GCR PF02155.10 ETO09363.1 - 0.12 11.1 0.1 0.14 10.8 0.1 1.3 1 1 0 1 1 1 0 Glucocorticoid receptor CheF-arch PF04283.7 ETO09364.1 - 3.3e-05 23.1 1.1 4.7e-05 22.7 0.8 1.1 1 0 0 1 1 1 1 Chemotaxis signal transduction system protein F from archaea CemA PF03040.9 ETO09364.1 - 0.0051 16.4 3.2 0.0051 16.4 2.2 1.7 1 1 1 2 2 2 1 CemA family Atg14 PF10186.4 ETO09364.1 - 0.5 9.2 6.7 0.84 8.5 4.6 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DHC_N1 PF08385.7 ETO09365.1 - 4.4e-18 64.9 1.4 4.9e-18 64.8 1.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 DUF2420 PF10336.4 ETO09365.1 - 0.15 11.6 1.4 0.73 9.4 0.3 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2420) DHC_N1 PF08385.7 ETO09366.1 - 4.6e-32 111.1 2.9 4.9e-32 111.0 2.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 DUF1825 PF08855.5 ETO09366.1 - 0.013 15.4 0.7 0.026 14.5 0.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1825) BACK PF07707.10 ETO09366.1 - 0.014 15.2 1.1 0.021 14.6 0.8 1.4 1 0 0 1 1 1 0 BTB And C-terminal Kelch Syntaxin_2 PF14523.1 ETO09366.1 - 1.1 9.3 4.6 3.8 7.5 3.2 1.9 1 1 0 1 1 1 0 Syntaxin-like protein IBR PF01485.16 ETO09367.1 - 0.13 12.1 5.6 0.46 10.3 3.9 2.0 1 1 0 1 1 1 0 IBR domain Macoilin PF09726.4 ETO09368.1 - 4.2 5.5 22.0 5.1 5.2 15.3 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF1885 PF08968.5 ETO09369.1 - 0.018 14.6 0.2 0.044 13.4 0.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1885) DUF3347 PF11827.3 ETO09369.1 - 0.39 10.6 7.9 0.44 10.5 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) MatE PF01554.13 ETO09371.1 - 0.14 11.7 8.9 0.64 9.6 5.8 2.0 1 1 0 1 1 1 0 MatE CDC45 PF02724.9 ETO09372.1 - 0.002 16.2 9.7 0.0026 15.8 6.7 1.0 1 0 0 1 1 1 1 CDC45-like protein DUF2890 PF11081.3 ETO09372.1 - 0.0029 17.7 7.9 0.0036 17.3 5.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2890) Tom37_C PF11801.3 ETO09372.1 - 0.011 15.6 1.5 0.013 15.3 1.0 1.1 1 0 0 1 1 1 0 Tom37 C-terminal domain Spt5_N PF11942.3 ETO09372.1 - 0.026 15.1 12.2 0.035 14.7 8.5 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal BSP_II PF05432.6 ETO09372.1 - 0.14 11.4 9.4 0.16 11.2 6.5 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) RR_TM4-6 PF06459.7 ETO09372.1 - 0.14 12.0 6.1 0.14 11.9 4.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop14 PF04147.7 ETO09372.1 - 0.27 9.0 10.7 0.32 8.8 7.4 1.0 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.6 ETO09372.1 - 0.51 9.2 19.9 0.67 8.8 13.8 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) HSP90 PF00183.13 ETO09372.1 - 1.2 7.4 17.4 1.6 7.0 12.1 1.0 1 0 0 1 1 1 0 Hsp90 protein SpoVR PF04293.8 ETO09372.1 - 1.4 7.1 8.8 1.8 6.8 6.1 1.1 1 0 0 1 1 1 0 SpoVR like protein Sec62 PF03839.11 ETO09372.1 - 1.5 8.1 5.9 1.8 7.8 4.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Sigma70_ner PF04546.8 ETO09372.1 - 1.5 8.3 12.3 1.9 8.0 8.5 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.1 ETO09372.1 - 2.6 8.3 14.7 4.8 7.5 10.2 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TLP-20 PF06088.6 ETO09372.1 - 8.3 6.0 10.5 11 5.6 7.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Ycf1 PF05758.7 ETO09372.1 - 9.6 3.7 9.4 11 3.5 6.5 1.0 1 0 0 1 1 1 0 Ycf1 PIH1 PF08190.7 ETO09373.1 - 1.4e-15 57.6 1.3 2.3e-15 56.8 0.8 1.5 1 1 0 1 1 1 1 pre-RNA processing PIH1/Nop17 Integrase_Zn PF02022.14 ETO09373.1 - 0.069 12.6 0.2 0.14 11.5 0.1 1.5 1 0 0 1 1 1 0 Integrase Zinc binding domain tRNA_anti-like PF12869.2 ETO09373.1 - 0.12 11.8 1.2 0.25 10.8 0.1 2.1 2 0 0 2 2 2 0 tRNA_anti-like cNMP_binding PF00027.24 ETO09374.1 - 2.4e-06 27.2 0.0 3.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Phospholip_B PF04916.8 ETO09375.1 - 3.7e-50 170.5 3.3 6.4e-50 169.8 2.3 1.3 1 1 0 1 1 1 1 Phospholipase B Phospholip_B PF04916.8 ETO09376.1 - 3.2e-32 111.3 0.6 3.7e-32 111.1 0.4 1.0 1 0 0 1 1 1 1 Phospholipase B DUF1798 PF08807.5 ETO09376.1 - 0.073 12.7 0.1 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) PGM_PMM_II PF02879.11 ETO09376.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II EF-hand_1 PF00036.27 ETO09377.1 - 5.8e-21 72.1 10.8 6.2e-08 31.3 0.4 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 ETO09377.1 - 1.9e-20 70.8 3.7 2.4e-08 33.1 0.2 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.1 ETO09377.1 - 7.8e-17 61.1 9.2 1.4e-08 34.7 1.6 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 ETO09377.1 - 2.6e-14 51.7 6.6 5.1e-07 28.7 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 ETO09377.1 - 1.2e-11 43.9 14.8 0.00015 21.2 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.1 ETO09377.1 - 4.6e-06 26.4 0.1 0.086 12.7 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 ETO09377.1 - 5.8e-06 26.3 0.8 0.024 14.6 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.8 ETO09377.1 - 0.00051 19.6 0.0 0.31 10.5 0.0 2.3 2 0 0 2 2 2 2 Caleosin related protein HARE-HTH PF05066.8 ETO09377.1 - 0.015 15.6 0.1 2.9 8.2 0.0 2.6 3 0 0 3 3 3 0 HB1, ASXL, restriction endonuclease HTH domain EF-hand_4 PF12763.2 ETO09377.1 - 0.034 13.8 4.5 0.32 10.7 0.4 2.6 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.13 ETO09377.1 - 0.1 12.3 0.0 0.1 12.3 0.0 3.9 5 0 0 5 5 5 0 Dockerin type I repeat DUF533 PF04391.7 ETO09377.1 - 0.1 11.9 0.7 0.15 11.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF533) B5 PF03484.10 ETO09377.1 - 0.13 12.1 0.7 6.6 6.6 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetase B5 domain Arm PF00514.18 ETO09378.1 - 8.2e-13 47.6 0.1 2.8e-05 23.7 0.0 3.4 3 0 0 3 3 3 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 ETO09378.1 - 0.015 15.5 0.0 7.3 6.9 0.0 2.3 2 0 0 2 2 2 0 HEAT repeats HEAT_EZ PF13513.1 ETO09378.1 - 0.068 13.6 0.0 0.92 10.0 0.0 2.5 3 0 0 3 3 3 0 HEAT-like repeat Podoplanin PF05808.6 ETO09379.1 - 2.1e-08 33.8 0.0 3.2e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Podoplanin TMEM154 PF15102.1 ETO09379.1 - 5e-05 23.0 0.1 8.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family CSF-1 PF05337.6 ETO09379.1 - 0.0014 18.0 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 Macrophage colony stimulating factor-1 (CSF-1) DUF4448 PF14610.1 ETO09379.1 - 0.017 14.6 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) SIT PF15330.1 ETO09379.1 - 0.026 14.6 1.1 0.26 11.4 0.0 2.4 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT STE3 PF02076.10 ETO09379.1 - 0.03 13.4 0.4 0.049 12.7 0.3 1.3 1 0 0 1 1 1 0 Pheromone A receptor CD34_antigen PF06365.7 ETO09379.1 - 0.03 13.9 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family BatD PF13584.1 ETO09379.1 - 0.065 11.8 0.1 0.095 11.2 0.1 1.2 1 0 0 1 1 1 0 Oxygen tolerance DUF4083 PF13314.1 ETO09379.1 - 0.066 13.0 4.1 0.11 12.2 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Epiglycanin_C PF14654.1 ETO09379.1 - 0.069 13.1 2.2 0.26 11.2 0.3 2.2 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region PepSY_TM_3 PF13706.1 ETO09379.1 - 0.074 12.4 3.7 0.13 11.7 2.6 1.4 1 0 0 1 1 1 0 PepSY-associated TM helix PHY PF00360.15 ETO09379.1 - 0.099 11.7 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Phytochrome region Rifin_STEVOR PF02009.11 ETO09379.1 - 0.11 12.0 0.3 0.16 11.5 0.1 1.3 1 1 0 1 1 1 0 Rifin/stevor family PepSY_TM_2 PF13703.1 ETO09379.1 - 0.18 11.9 2.9 0.3 11.2 2.0 1.3 1 0 0 1 1 1 0 PepSY-associated TM helix DUF515 PF04415.7 ETO09379.1 - 0.21 9.8 1.1 0.36 9.0 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SKG6 PF08693.5 ETO09379.1 - 0.31 10.3 6.4 0.99 8.7 4.4 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain gpUL132 PF11359.3 ETO09379.1 - 0.71 9.1 7.0 0.032 13.5 1.1 1.5 2 0 0 2 2 2 0 Glycoprotein UL132 Tubulin PF00091.20 ETO09380.1 - 3.2e-67 226.5 0.0 5.6e-67 225.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO09380.1 - 1.6e-35 121.8 0.0 2.7e-35 121.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 ETO09380.1 - 0.042 13.9 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain ABC2_membrane PF01061.19 ETO09381.1 - 5.6e-15 55.0 19.1 5.6e-15 55.0 13.3 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 ETO09381.1 - 2.6e-07 31.0 0.8 5.4e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.2 ETO09381.1 - 0.0017 17.5 20.3 0.0017 17.5 14.1 2.1 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_29 PF13555.1 ETO09382.1 - 0.0011 18.4 0.0 0.0025 17.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Phosphoprotein PF00922.12 ETO09382.1 - 0.0012 18.0 0.9 0.0018 17.5 0.6 1.3 1 0 0 1 1 1 1 Vesiculovirus phosphoprotein AAA_22 PF13401.1 ETO09382.1 - 0.0059 16.7 0.4 0.019 15.0 0.1 2.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETO09382.1 - 0.0088 16.0 0.1 0.018 15.0 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 ETO09382.1 - 0.0096 15.3 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein G-alpha PF00503.15 ETO09382.1 - 0.012 14.2 3.2 0.013 14.1 1.6 1.4 1 1 0 1 1 1 0 G-protein alpha subunit DUF258 PF03193.11 ETO09382.1 - 0.018 14.2 0.0 0.036 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PduV-EutP PF10662.4 ETO09382.1 - 0.023 14.1 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 ETO09382.1 - 0.024 14.9 0.8 0.024 14.9 0.6 2.1 1 1 1 2 2 2 0 ABC transporter Zeta_toxin PF06414.7 ETO09382.1 - 0.024 13.7 0.0 0.067 12.2 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.1 ETO09382.1 - 0.036 13.6 1.3 0.39 10.2 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.9 ETO09382.1 - 0.13 11.9 1.7 3 7.5 0.0 3.1 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) CENP-Q PF13094.1 ETO09382.1 - 0.2 11.6 5.2 0.23 11.4 1.0 2.3 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit MSC PF09402.5 ETO09383.1 - 0.0043 15.8 1.3 0.0066 15.1 0.1 1.7 2 0 0 2 2 2 1 Man1-Src1p-C-terminal domain YMF19 PF02326.10 ETO09383.1 - 7 7.3 7.6 0.43 11.1 0.9 2.2 3 0 0 3 3 3 0 Plant ATP synthase F0 TLD PF07534.11 ETO09384.1 - 1.9e-09 37.6 0.0 5.4e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 TLD COG2 PF06148.6 ETO09384.1 - 0.0057 16.5 3.5 0.012 15.4 2.5 1.5 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 ArdA PF07275.6 ETO09384.1 - 0.065 13.4 3.8 0.14 12.4 2.6 1.5 1 0 0 1 1 1 0 Antirestriction protein (ArdA) Lge1 PF11488.3 ETO09384.1 - 0.83 9.8 5.1 3.1 8.0 2.2 2.5 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 IncA PF04156.9 ETO09384.1 - 1.3 8.5 5.5 2.2 7.8 3.8 1.3 1 0 0 1 1 1 0 IncA protein zf-PARP PF00645.13 ETO09384.1 - 2.6 8.3 10.4 0.26 11.5 0.7 3.2 2 1 0 2 2 2 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Cation_ATPase_C PF00689.16 ETO09386.1 - 2.9e-44 150.7 9.3 2.9e-44 150.7 6.5 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 ETO09386.1 - 1.1e-27 97.9 0.1 1.8e-27 97.1 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETO09386.1 - 5.3e-16 58.3 0.0 1.3e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 ETO09386.1 - 2.5e-13 50.6 0.0 9.5e-13 48.7 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 ETO09386.1 - 1.4e-09 37.9 1.5 2e-06 27.5 0.5 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 ETO09386.1 - 0.0032 17.3 0.0 0.017 14.9 0.0 2.3 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 ETO09386.1 - 0.0067 16.6 0.0 0.023 14.9 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase cNMP_binding PF00027.24 ETO09387.1 - 5.2e-54 180.0 0.2 2.8e-19 68.7 0.0 3.3 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Cupin_2 PF07883.6 ETO09387.1 - 0.011 15.2 0.0 9.6 5.7 0.0 3.1 3 0 0 3 3 3 0 Cupin domain Pkinase PF00069.20 ETO09388.1 - 4.2e-14 52.3 0.0 9.9e-14 51.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO09388.1 - 1.3e-06 27.6 0.1 2.2e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase bcl-2I13 PF12201.3 ETO09388.1 - 0.068 12.6 0.1 0.19 11.1 0.0 1.7 2 0 0 2 2 2 0 Bcl2-interacting killer, BH3-domain containing FH2 PF02181.18 ETO09389.1 - 4.2e-68 229.9 13.2 4.2e-68 229.9 9.2 1.8 1 1 1 2 2 2 1 Formin Homology 2 Domain HHH_6 PF14579.1 ETO09389.1 - 0.11 12.6 0.4 2.6 8.1 0.0 2.6 3 0 0 3 3 3 0 Helix-hairpin-helix motif FlaC_arch PF05377.6 ETO09389.1 - 0.42 10.5 5.9 0.48 10.3 0.3 3.5 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF2203 PF09969.4 ETO09389.1 - 0.6 10.3 11.5 0.28 11.4 2.4 3.0 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) RhoGAP PF00620.22 ETO09392.1 - 2e-19 69.7 0.1 4e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Daxx PF03344.10 ETO09392.1 - 2e-05 23.2 25.0 2e-05 23.2 17.4 2.1 2 0 0 2 2 2 1 Daxx Family SDA1 PF05285.7 ETO09392.1 - 9.5e-05 21.8 25.0 9.5e-05 21.8 17.4 2.1 2 0 0 2 2 2 1 SDA1 Zip PF02535.17 ETO09392.1 - 0.11 11.4 1.4 0.21 10.5 0.1 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter Nop14 PF04147.7 ETO09392.1 - 1 7.1 38.6 0.39 8.5 23.9 2.0 2 0 0 2 2 2 0 Nop14-like family DUF2457 PF10446.4 ETO09392.1 - 5.1 5.7 46.7 0.058 12.1 26.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 ETO09392.1 - 6.2 4.7 30.3 0.91 7.4 17.2 2.0 2 0 0 2 2 2 0 CDC45-like protein CobT PF06213.7 ETO09392.1 - 6.5 5.7 31.5 0.12 11.4 16.5 2.0 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Utp14 PF04615.8 ETO09392.1 - 7.8 4.5 32.1 0.77 7.8 17.1 2.0 2 0 0 2 2 2 0 Utp14 protein Arm PF00514.18 ETO09393.1 - 5.6e-05 22.8 3.1 3.8 7.4 0.0 5.3 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 ETO09393.1 - 0.00028 21.1 0.0 0.0062 16.7 0.0 2.9 2 1 1 3 3 3 1 HEAT repeats V-ATPase_H_N PF03224.9 ETO09393.1 - 0.015 14.4 1.3 0.034 13.2 0.2 2.4 2 1 0 2 2 2 0 V-ATPase subunit H B-block_TFIIIC PF04182.7 ETO09393.1 - 0.036 13.8 0.1 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC V-ATPase_H_C PF11698.3 ETO09393.1 - 0.061 13.2 3.3 1.1 9.1 0.0 3.3 3 1 0 3 3 3 0 V-ATPase subunit H PWI PF01480.12 ETO09393.1 - 0.094 12.8 2.2 0.23 11.5 0.2 2.4 2 0 0 2 2 2 0 PWI domain TauE PF01925.14 ETO09394.1 - 4.2e-06 26.3 0.8 4.2e-06 26.3 0.5 1.6 2 0 0 2 2 2 1 Sulfite exporter TauE/SafE JTB PF05439.7 ETO09395.1 - 0.4 10.4 3.8 0.83 9.4 2.6 1.5 1 0 0 1 1 1 0 Jumping translocation breakpoint protein (JTB) DnaB_2 PF07261.6 ETO09396.1 - 0.0062 16.1 0.4 0.25 10.9 0.0 2.7 2 1 1 3 3 3 2 Replication initiation and membrane attachment Arteri_env PF01606.11 ETO09396.1 - 0.035 13.7 0.1 0.051 13.2 0.1 1.2 1 0 0 1 1 1 0 Arterivirus envelope protein Methyltransf_3 PF01596.12 ETO09398.1 - 3.5e-62 209.1 0.2 4.4e-62 208.7 0.1 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 ETO09398.1 - 1.2e-13 51.8 0.0 1.9e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO09398.1 - 5.4e-10 39.8 0.0 9.9e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO09398.1 - 2.3e-07 30.4 0.1 3.6e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 ETO09398.1 - 0.00079 18.5 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Spermine_synth PF01564.12 ETO09398.1 - 0.0012 17.8 0.2 0.022 13.7 0.1 2.2 1 1 1 2 2 2 1 Spermine/spermidine synthase GCD14 PF08704.5 ETO09398.1 - 0.0013 18.2 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_11 PF08241.7 ETO09398.1 - 0.0027 18.1 0.0 0.0069 16.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO09398.1 - 0.0053 17.2 0.0 0.016 15.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 ETO09398.1 - 0.012 15.1 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.10 ETO09398.1 - 0.022 14.1 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Ubie_methyltran PF01209.13 ETO09398.1 - 0.032 13.3 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF633 PF04816.7 ETO09398.1 - 0.038 13.3 0.0 0.074 12.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF633) Methyltransf_26 PF13659.1 ETO09398.1 - 0.095 12.7 0.0 0.16 11.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 ETO09398.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FAM176 PF14851.1 ETO09399.1 - 0.022 14.4 0.2 0.022 14.4 0.1 3.8 3 2 2 5 5 5 0 FAM176 family Conotoxin PF02950.12 ETO09399.1 - 0.043 14.6 0.7 0.043 14.6 0.5 3.2 4 0 0 4 4 4 0 Conotoxin DUF843 PF05814.6 ETO09399.1 - 0.046 13.5 2.0 0.071 12.9 0.2 2.1 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) OAD_gamma PF04277.8 ETO09399.1 - 0.18 12.2 0.2 1.4 9.3 0.0 2.7 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DUF4023 PF13215.1 ETO09399.1 - 0.51 10.1 9.0 1.4 8.7 3.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4023) Hum_adeno_E3A PF05393.6 ETO09399.1 - 0.61 9.7 3.6 0.57 9.8 0.9 2.0 2 1 0 2 2 2 0 Human adenovirus early E3A glycoprotein Ctr PF04145.10 ETO09399.1 - 8.2 6.4 8.5 2.9 7.9 2.6 2.6 1 1 1 2 2 2 0 Ctr copper transporter family MRG PF05712.8 ETO09400.1 - 1.2e-14 53.6 0.2 3.8e-14 52.0 0.2 1.8 1 0 0 1 1 1 1 MRG DUF3464 PF11947.3 ETO09401.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Trypan_PARP PF05887.6 ETO09402.1 - 0.27 11.0 2.4 0.62 9.8 1.7 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) zf-DHHC PF01529.15 ETO09403.1 - 7e-25 87.4 18.3 7e-25 87.4 12.7 3.1 3 1 1 4 4 4 1 DHHC palmitoyltransferase tRNA-synt_2b PF00587.20 ETO09404.1 - 2.4e-08 33.7 0.1 4.8e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_His PF13393.1 ETO09404.1 - 3e-07 29.8 0.0 3.7e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase DUF1601 PF07671.6 ETO09404.1 - 0.096 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1601) BLVR PF06375.6 ETO09404.1 - 0.17 11.6 13.3 0.31 10.8 9.2 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Enterotoxin_ST PF02048.11 ETO09404.1 - 0.62 10.3 2.7 1.2 9.4 1.9 1.5 1 0 0 1 1 1 0 Heat-stable enterotoxin ST FAM176 PF14851.1 ETO09404.1 - 0.84 9.3 4.5 1.3 8.6 3.1 1.4 1 0 0 1 1 1 0 FAM176 family Protocadherin PF08374.6 ETO09404.1 - 1.1 8.8 6.1 1.3 8.5 4.2 1.2 1 0 0 1 1 1 0 Protocadherin Ldh_1_C PF02866.13 ETO09405.1 - 7.4e-29 100.6 0.9 5.4e-19 68.5 0.2 2.3 2 0 0 2 2 2 2 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 ETO09405.1 - 9.6e-26 90.2 0.0 7.8e-17 61.4 0.0 2.4 2 0 0 2 2 2 2 lactate/malate dehydrogenase, NAD binding domain Pkinase PF00069.20 ETO09406.1 - 1.5e-31 109.4 0.0 2.5e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO09406.1 - 5.4e-06 25.6 0.1 1.1e-05 24.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase DUF869 PF05911.6 ETO09407.1 - 0.0055 15.0 0.5 0.0063 14.8 0.4 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) CMAS PF02353.15 ETO09409.1 - 2.5e-25 89.0 0.1 3.6e-25 88.5 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 ETO09409.1 - 0.00015 22.2 0.0 0.00024 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO09409.1 - 0.0015 18.9 0.0 0.003 18.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETO09409.1 - 0.0086 15.8 0.0 0.014 15.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Pkinase PF00069.20 ETO09411.1 - 1.5e-25 89.8 0.0 1.7e-25 89.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO09411.1 - 3.6e-07 29.5 0.0 4.7e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO09411.1 - 0.14 11.1 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Kinase-like CTP_transf_2 PF01467.21 ETO09412.1 - 8.6e-10 38.8 1.1 3.7e-09 36.8 0.8 2.0 1 1 0 1 1 1 1 Cytidylyltransferase YopR_core PF09025.5 ETO09412.1 - 0.071 13.0 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 YopR Core RasGAP PF00616.14 ETO09413.1 - 1.5e-07 31.3 0.1 1.5e-07 31.3 0.0 1.5 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase DUF4363 PF14276.1 ETO09413.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) RasGAP PF00616.14 ETO09414.1 - 1.5e-28 99.8 0.0 7.6e-28 97.5 0.0 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase Nucleoplasmin PF03066.10 ETO09414.1 - 0.005 16.3 0.4 0.0084 15.6 0.3 1.3 1 0 0 1 1 1 1 Nucleoplasmin adh_short_C2 PF13561.1 ETO09418.1 - 1.4e-17 64.3 0.0 2e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase CDC14 PF08045.6 ETO09418.1 - 0.047 12.8 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 Cell division control protein 14, SIN component RNA_pol_L_2 PF13656.1 ETO09419.1 - 0.027 13.8 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Zip PF02535.17 ETO09420.1 - 0.54 9.2 10.5 1 8.2 7.3 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter His_Phos_1 PF00300.17 ETO09421.1 - 1.3e-14 54.6 0.0 2.6e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Sulfatase PF00884.18 ETO09422.1 - 0.00016 20.9 0.2 0.00045 19.5 0.0 1.7 2 0 0 2 2 2 1 Sulfatase SPT16 PF08644.6 ETO09423.1 - 0.085 12.6 0.4 0.085 12.6 0.3 2.2 3 0 0 3 3 3 0 FACT complex subunit (SPT16/CDC68) Macoilin PF09726.4 ETO09423.1 - 2.6 6.2 19.7 3.4 5.8 13.7 1.1 1 0 0 1 1 1 0 Transmembrane protein SR-25 PF10500.4 ETO09423.1 - 3.5 7.0 30.2 5.1 6.4 20.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.20 ETO09424.1 - 5.3e-11 42.1 0.1 1e-10 41.2 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Hom_end_hint PF05203.11 ETO09425.1 - 0.028 14.1 4.9 0.029 14.1 3.4 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint Cas_DxTHG PF09455.5 ETO09425.1 - 0.036 13.2 1.2 0.043 12.9 0.8 1.0 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Daxx PF03344.10 ETO09425.1 - 0.13 10.7 12.8 0.15 10.5 8.9 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 ETO09425.1 - 0.21 9.6 8.5 0.21 9.5 5.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Upf2 PF04050.9 ETO09425.1 - 0.25 11.1 13.7 0.29 10.8 9.5 1.2 1 0 0 1 1 1 0 Up-frameshift suppressor 2 Cellulose_synt PF03552.9 ETO09425.1 - 0.27 9.5 4.5 0.32 9.2 3.1 1.0 1 0 0 1 1 1 0 Cellulose synthase TRAP_alpha PF03896.11 ETO09425.1 - 0.59 9.0 7.2 0.68 8.8 5.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2890 PF11081.3 ETO09425.1 - 0.6 10.1 11.7 0.79 9.7 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) FGF-BP1 PF06473.7 ETO09425.1 - 1.6 8.2 11.7 2 7.9 8.1 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) DHHW PF14286.1 ETO09425.1 - 9 5.4 8.8 11 5.2 6.1 1.1 1 0 0 1 1 1 0 DHHW protein Pico_P1A PF02226.11 ETO09426.1 - 0.084 12.6 0.4 0.2 11.3 0.3 1.6 1 0 0 1 1 1 0 Picornavirus coat protein (VP4) KilA-N PF04383.8 ETO09426.1 - 0.68 9.5 7.8 6.5 6.4 4.9 2.3 1 1 1 2 2 2 0 KilA-N domain DUF3403 PF11883.3 ETO09426.1 - 0.78 10.0 2.8 0.58 10.4 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3403) Sec8_exocyst PF04048.9 ETO09427.1 - 8.8e-09 35.1 1.5 1.1e-07 31.6 0.1 2.6 1 1 1 2 2 2 1 Sec8 exocyst complex component specific domain PMC2NT PF08066.7 ETO09427.1 - 2.5 8.4 6.1 0.47 10.7 0.3 2.6 3 0 0 3 3 3 0 PMC2NT (NUC016) domain RRM_1 PF00076.17 ETO09431.1 - 1.2e-33 114.5 4.5 7.8e-13 47.8 0.0 3.8 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO09431.1 - 1.3e-24 85.9 1.0 5.5e-09 35.8 0.0 4.0 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO09431.1 - 5.6e-15 54.9 2.3 2e-05 24.3 0.0 4.4 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 ETO09431.1 - 0.00018 21.3 3.6 0.93 9.3 0.0 3.7 3 0 0 3 3 3 3 RNA binding motif Nup35_RRM_2 PF14605.1 ETO09431.1 - 0.0012 18.6 2.2 3.6 7.4 0.0 3.7 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif VID27 PF08553.5 ETO09432.1 - 7.3e-71 239.4 0.2 8.8e-71 239.2 0.1 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein WD40 PF00400.27 ETO09432.1 - 0.0007 19.3 0.0 0.0042 16.9 0.0 2.3 3 0 0 3 3 3 1 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO09432.1 - 0.004 15.5 0.0 0.0064 14.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain VID27 PF08553.5 ETO09433.1 - 0.018 13.3 11.4 0.021 13.1 7.9 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Gcd10p PF04189.8 ETO09433.1 - 0.12 11.4 3.8 0.14 11.2 2.6 1.2 1 0 0 1 1 1 0 Gcd10p family FAM176 PF14851.1 ETO09433.1 - 0.17 11.5 4.4 0.3 10.7 3.0 1.5 1 0 0 1 1 1 0 FAM176 family DUF3449 PF11931.3 ETO09433.1 - 0.19 11.2 4.6 0.28 10.6 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) CENP-T PF15511.1 ETO09433.1 - 0.38 9.9 8.6 0.42 9.8 6.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T BSP_II PF05432.6 ETO09433.1 - 0.46 9.7 12.8 0.56 9.4 8.9 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CDC45 PF02724.9 ETO09433.1 - 0.71 7.8 11.0 0.72 7.8 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2722 PF10846.3 ETO09433.1 - 0.98 8.3 6.2 0.98 8.3 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) NOA36 PF06524.7 ETO09433.1 - 1.4 8.1 14.2 1.6 7.9 9.9 1.3 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 ETO09433.1 - 1.8 6.3 19.5 2.1 6.1 13.5 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 ETO09433.1 - 2.2 7.4 17.3 2.7 7.1 12.0 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.5 ETO09433.1 - 3.6 6.5 13.7 4.1 6.3 9.5 1.1 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 ETO09433.1 - 4.1 5.7 18.1 4.3 5.6 12.5 1.1 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 ETO09433.1 - 5 5.7 22.6 5.9 5.4 15.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) EBV-NA3 PF05009.7 ETO09433.1 - 5.2 6.2 7.3 6.8 5.8 5.0 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) RRN3 PF05327.6 ETO09433.1 - 7.9 4.4 10.0 8.5 4.3 7.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ImcF-related_N PF14331.1 ETO09434.1 - 0.1 11.5 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 ImcF-related N-terminal domain Myb_Cef PF11831.3 ETO09436.1 - 0.16 11.1 6.3 0.25 10.5 4.4 1.2 1 0 0 1 1 1 0 pre-mRNA splicing factor component WD40 PF00400.27 ETO09438.1 - 4.7e-65 213.3 22.7 1.5e-12 46.8 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO09438.1 - 6.8e-10 38.9 6.3 1.5e-06 28.0 0.0 4.0 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO09438.1 - 1.8e-06 26.3 6.0 0.2 9.7 0.1 4.2 2 2 2 4 4 4 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO09438.1 - 7.9e-06 24.3 1.0 0.052 11.8 0.1 3.2 1 1 1 3 3 3 3 Cytochrome D1 heme domain SGL PF08450.7 ETO09438.1 - 6.1e-05 22.5 0.4 0.062 12.6 0.0 2.8 2 1 1 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region Resistin PF06954.6 ETO09438.1 - 0.00017 21.7 3.4 0.45 10.8 0.1 3.9 2 2 2 4 4 4 2 Resistin PD40 PF07676.7 ETO09438.1 - 0.00082 18.9 6.7 22 4.8 0.0 5.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO09438.1 - 0.019 14.4 0.1 7.1 6.0 0.0 2.8 1 1 0 1 1 1 0 PQQ-like domain DUF4024 PF13216.1 ETO09438.1 - 0.033 13.9 0.3 0.069 12.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4024) UPF0179 PF03684.8 ETO09438.1 - 0.11 12.0 1.3 0.54 9.8 0.1 2.4 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0179) WD40 PF00400.27 ETO09439.1 - 1.2e-12 47.2 3.8 3.3e-09 36.2 0.3 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO09439.1 - 0.00049 18.3 0.1 0.00063 17.9 0.1 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 IU_nuc_hydro PF01156.14 ETO09440.1 - 5.7e-14 52.0 0.0 6.4e-14 51.8 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF3591 PF12157.3 ETO09442.1 - 6.8e-31 107.1 1.5 1.7e-24 86.1 0.2 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF3591) XK-related PF09815.4 ETO09443.1 - 0.02 13.9 0.1 0.027 13.4 0.1 1.3 1 0 0 1 1 1 0 XK-related protein DUF3658 PF12395.3 ETO09443.1 - 0.02 14.4 0.3 0.049 13.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function NDK PF00334.14 ETO09443.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Nucleoside diphosphate kinase SAM_2 PF07647.12 ETO09444.1 - 0.00013 21.7 0.1 0.00026 20.7 0.1 1.5 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO09444.1 - 0.008 16.3 0.3 0.013 15.7 0.1 1.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DUF2606 PF10794.4 ETO09444.1 - 0.11 11.9 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) RabGAP-TBC PF00566.13 ETO09445.1 - 5.4e-23 81.5 0.4 6.2e-23 81.3 0.3 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain HTH_32 PF13565.1 ETO09446.1 - 0.071 13.9 0.3 0.27 12.0 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain DUF1201 PF06716.6 ETO09448.1 - 1.1 9.1 11.6 9 6.1 4.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) Herpes_LMP1 PF05297.6 ETO09452.1 - 0.97 8.2 9.4 1.3 7.8 6.3 1.4 1 1 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Mito_carr PF00153.22 ETO09453.1 - 1e-65 217.4 1.4 2.9e-22 78.1 0.0 3.3 2 1 1 3 3 3 3 Mitochondrial carrier protein RasGEF PF00617.14 ETO09454.1 - 3.6e-21 75.7 0.1 4.6e-21 75.4 0.1 1.1 1 0 0 1 1 1 1 RasGEF domain Glycolytic PF00274.14 ETO09455.1 - 0.077 11.3 0.0 0.098 11.0 0.0 1.1 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I DUF1598 PF07643.6 ETO09457.1 - 0.013 15.5 0.1 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1598) Hid1 PF12722.2 ETO09457.1 - 1.6 6.3 12.9 1.9 6.0 9.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Mitofilin PF09731.4 ETO09457.1 - 1.9 7.0 23.6 3.2 6.2 16.4 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Daxx PF03344.10 ETO09457.1 - 3 6.2 37.9 5.3 5.4 22.6 2.0 2 0 0 2 2 2 0 Daxx Family IFT57 PF10498.4 ETO09457.1 - 3 6.4 21.3 0.92 8.1 12.8 1.6 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Pilt PF15453.1 ETO09457.1 - 4.5 6.8 15.4 6 6.4 10.7 1.3 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions PLRV_ORF5 PF01690.12 ETO09457.1 - 5.2 6.0 14.8 7.3 5.6 10.3 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein TFIIF_alpha PF05793.7 ETO09457.1 - 6.9 4.9 36.9 3 6.1 24.0 1.4 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2457 PF10446.4 ETO09457.1 - 9.3 4.8 26.6 13 4.4 18.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Acyl-CoA_dh_1 PF00441.19 ETO09460.1 - 4.3e-23 82.0 0.2 7.2e-23 81.3 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 ETO09460.1 - 2.4e-05 24.6 0.1 3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain TnpB_IS66 PF05717.8 ETO09460.1 - 0.0082 15.5 0.6 0.91 8.9 0.1 2.4 1 1 1 2 2 2 2 IS66 Orf2 like protein Acyl-CoA_dh_M PF02770.14 ETO09460.1 - 0.03 13.8 0.0 0.072 12.6 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain NAPRTase PF04095.11 ETO09461.1 - 5.9e-31 107.6 0.0 1.6e-16 60.3 0.0 2.3 1 1 1 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family Flp_N PF03930.9 ETO09461.1 - 0.062 13.0 0.2 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 Recombinase Flp protein N-terminus RAB3GAP2_N PF14655.1 ETO09462.1 - 0.025 13.5 0.1 0.032 13.2 0.1 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus E7 PF00527.13 ETO09462.1 - 0.2 11.8 1.9 0.35 11.0 1.3 1.4 1 0 0 1 1 1 0 E7 protein, Early protein PBP1_TM PF14812.1 ETO09462.1 - 3.5 8.0 6.7 2.1 8.7 0.9 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal His_Phos_1 PF00300.17 ETO09463.1 - 1.9e-06 28.0 5.3 1.9e-06 28.0 3.7 2.0 1 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) WTX PF09422.5 ETO09463.1 - 0.0014 17.7 2.5 0.0019 17.2 1.7 1.2 1 0 0 1 1 1 1 WTX protein Spt5_N PF11942.3 ETO09463.1 - 0.36 11.4 4.3 0.2 12.2 1.0 2.0 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal NRDE PF05742.7 ETO09464.1 - 5.1e-23 81.7 0.1 1.6e-12 47.2 0.0 2.2 1 1 1 2 2 2 2 NRDE protein KilA-N PF04383.8 ETO09464.1 - 0.0035 16.9 0.2 0.0086 15.6 0.2 1.8 1 1 0 1 1 1 1 KilA-N domain Acetyltransf_1 PF00583.19 ETO09465.1 - 7.1e-11 41.9 0.0 1.4e-10 41.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETO09465.1 - 3.7e-06 27.0 0.0 8.4e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETO09465.1 - 9.8e-05 22.4 0.0 0.0033 17.5 0.0 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETO09465.1 - 0.00061 19.6 0.0 0.012 15.5 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 ETO09465.1 - 0.002 18.2 0.7 0.64 10.1 0.0 2.4 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETO09465.1 - 0.015 15.0 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.1 ETO09465.1 - 0.022 14.6 0.0 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase SAM_2 PF07647.12 ETO09466.1 - 0.003 17.3 0.0 0.015 15.0 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO09466.1 - 0.029 14.5 0.0 0.071 13.2 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF106 PF01956.11 ETO09466.1 - 0.097 12.2 0.6 0.19 11.2 0.2 1.6 2 0 0 2 2 2 0 Integral membrane protein DUF106 Plasmid_killer PF05015.8 ETO09466.1 - 0.5 10.5 3.3 0.23 11.6 0.6 1.7 2 0 0 2 2 2 0 Plasmid maintenance system killer protein DAG_kinase_N PF14513.1 ETO09466.1 - 0.86 9.7 6.3 2 8.5 4.4 1.6 1 1 0 1 1 1 0 Diacylglycerol kinase N-terminus Actin PF00022.14 ETO09467.1 - 6.2e-32 110.4 0.1 1e-31 109.7 0.1 1.3 1 1 0 1 1 1 1 Actin DUF607 PF04678.8 ETO09468.1 - 0.44 10.4 5.9 0.47 10.3 0.6 2.8 2 0 0 2 2 2 0 Protein of unknown function, DUF607 ELO PF01151.13 ETO09469.1 - 5.7e-12 45.4 7.6 7.3e-12 45.1 5.3 1.2 1 0 0 1 1 1 1 GNS1/SUR4 family TAS2R PF05296.8 ETO09469.1 - 0.067 12.0 7.1 0.095 11.5 4.9 1.2 1 0 0 1 1 1 0 Mammalian taste receptor protein (TAS2R) TPR_11 PF13414.1 ETO09471.1 - 9.4e-05 21.9 0.0 0.00023 20.7 0.0 1.6 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 ETO09471.1 - 0.0061 16.3 0.1 0.016 15.0 0.1 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO09471.1 - 0.091 12.4 0.1 0.2 11.3 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETO09471.1 - 0.12 12.3 0.0 0.57 10.1 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Sigma_reg_N PF13800.1 ETO09471.1 - 0.48 10.4 3.9 5.7 7.0 0.0 3.3 2 1 1 3 3 3 0 Sigma factor regulator N-terminal EF-hand_7 PF13499.1 ETO09472.1 - 1.1e-08 35.0 6.6 1.8e-07 31.2 0.6 3.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO09472.1 - 4e-08 32.0 1.6 2.9e-05 23.0 0.1 4.1 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.1 ETO09472.1 - 1.6e-07 30.6 2.3 0.00018 21.1 0.1 4.1 4 0 0 4 4 4 1 EF-hand domain EF-hand_5 PF13202.1 ETO09472.1 - 2.4e-06 26.6 2.8 7.1e-05 21.9 0.2 3.4 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.1 ETO09472.1 - 0.0021 17.6 0.9 0.2 11.3 0.2 3.4 3 1 1 4 4 4 1 EF-hand domain pair DDRGK PF09756.4 ETO09472.1 - 0.039 13.3 0.4 0.1 12.0 0.3 1.7 1 0 0 1 1 1 0 DDRGK domain EF-hand_2 PF09068.6 ETO09472.1 - 2.8 8.0 5.9 0.5 10.4 0.2 2.4 2 2 0 2 2 2 0 EF hand SNARE_assoc PF09335.6 ETO09473.1 - 1.1e-05 25.5 1.9 0.007 16.5 0.2 2.1 1 1 0 2 2 2 2 SNARE associated Golgi protein DUF2206 PF09971.4 ETO09473.1 - 0.0011 17.8 0.2 0.0013 17.6 0.1 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2206) O-ag_pol_Wzy PF14296.1 ETO09473.1 - 0.0094 14.5 0.4 0.012 14.2 0.3 1.1 1 0 0 1 1 1 1 O-antigen polysaccharide polymerase Wzy TMEM210 PF15195.1 ETO09473.1 - 0.022 14.8 0.0 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 TMEM210 family Plasmodium_Vir PF05795.6 ETO09473.1 - 0.04 13.1 0.0 0.054 12.6 0.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF106 PF01956.11 ETO09473.1 - 0.78 9.2 3.3 3.9 6.9 2.3 1.9 1 1 0 1 1 1 0 Integral membrane protein DUF106 Ras PF00071.17 ETO09474.1 - 6.5e-24 84.1 0.0 8.8e-23 80.4 0.0 2.1 2 0 0 2 2 2 1 Ras family Miro PF08477.8 ETO09474.1 - 0.00046 20.6 0.0 0.0011 19.4 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein WD40 PF00400.27 ETO09475.1 - 1.5e-36 122.9 11.6 1.9e-13 49.6 0.0 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO09475.1 - 3e-08 32.2 1.4 0.0016 16.6 1.1 2.7 1 1 0 2 2 2 2 Nucleoporin Nup120/160 RED_C PF07807.6 ETO09475.1 - 0.06 13.5 0.0 17 5.6 0.0 2.5 3 0 0 3 3 3 0 RED-like protein C-terminal region DUF3601 PF12208.3 ETO09475.1 - 0.064 13.1 0.0 0.22 11.5 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3601) GST_N_3 PF13417.1 ETO09476.1 - 3.5e-12 46.3 0.0 7.9e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETO09476.1 - 3.5e-11 42.9 0.1 1.5e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 ETO09476.1 - 5.7e-08 32.6 0.5 1.2e-07 31.6 0.4 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 ETO09476.1 - 1.6e-05 25.3 0.0 4.8e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETO09476.1 - 1.7e-05 24.5 0.1 5.5e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF1129 PF06570.6 ETO09477.1 - 0.0097 15.2 1.7 0.012 14.9 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) Saw1 PF11561.3 ETO09477.1 - 0.017 14.5 4.0 0.018 14.4 2.8 1.1 1 0 0 1 1 1 0 Single strand annealing-weakened 1 RecO_C PF02565.10 ETO09477.1 - 0.12 12.2 0.1 0.22 11.3 0.0 1.5 2 0 0 2 2 2 0 Recombination protein O C terminal DUF4263 PF14082.1 ETO09477.1 - 0.19 11.6 4.6 0.81 9.6 3.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4263) Spore_coat_CotO PF14153.1 ETO09477.1 - 0.21 11.0 9.6 0.24 10.8 6.7 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF1911 PF08929.5 ETO09477.1 - 0.51 11.0 6.2 0.65 10.7 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1911) Peroxin-13_N PF04088.8 ETO09477.1 - 1.3 8.9 3.9 1.7 8.5 2.7 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Sugar_tr PF00083.19 ETO09477.1 - 2.2 6.7 4.1 2.6 6.5 2.9 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter Porph_ging PF09697.5 ETO09477.1 - 4 7.6 6.1 40 4.4 4.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (Porph_ging) SDP_N PF12278.3 ETO09477.1 - 4.8 6.7 10.0 6.1 6.4 6.9 1.1 1 0 0 1 1 1 0 Sex determination protein N terminal FAM176 PF14851.1 ETO09478.1 - 0.31 10.7 3.5 13 5.4 0.2 2.8 3 0 0 3 3 3 0 FAM176 family Cellulose_synt PF03552.9 ETO09478.1 - 7.1 4.7 6.4 5.2 5.2 0.1 2.1 1 1 0 2 2 2 0 Cellulose synthase PH PF00169.24 ETO09480.1 - 2.9e-10 40.2 0.3 5.1e-10 39.4 0.2 1.4 1 0 0 1 1 1 1 PH domain RhoGEF PF00621.15 ETO09480.1 - 6.7e-08 32.6 0.9 1.9e-07 31.1 0.2 2.1 2 1 0 2 2 2 1 RhoGEF domain PH_11 PF15413.1 ETO09480.1 - 0.0055 16.9 0.6 0.02 15.1 0.1 2.3 2 1 0 2 2 2 1 Pleckstrin homology domain DUF2338 PF10100.4 ETO09481.1 - 0.00029 19.3 0.4 0.00044 18.7 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2338) PDEase_I PF00233.14 ETO09481.1 - 0.044 13.5 3.4 0.062 13.0 2.1 1.5 1 1 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase DUF1722 PF08349.6 ETO09481.1 - 0.072 12.9 2.9 0.078 12.8 1.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1722) Amidase PF01425.16 ETO09482.1 - 0.0035 16.2 0.1 0.007 15.2 0.0 1.4 1 1 0 1 1 1 1 Amidase M_domain PF12938.2 ETO09483.1 - 0.026 14.3 4.2 0.05 13.4 2.9 1.3 1 0 0 1 1 1 0 M domain of GW182 PPV_E1_N PF00524.13 ETO09483.1 - 0.033 14.4 1.7 0.033 14.4 1.2 2.4 2 1 0 2 2 1 0 E1 Protein, N terminal domain SpoVAD PF07451.6 ETO09483.1 - 0.062 11.7 0.0 0.094 11.1 0.0 1.2 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) TMCO5 PF14992.1 ETO09483.1 - 0.14 11.2 28.4 0.35 9.9 19.6 1.5 1 1 0 1 1 1 0 TMCO5 family Laminin_II PF06009.7 ETO09483.1 - 0.17 11.6 16.5 0.093 12.4 1.3 2.7 1 1 0 2 2 2 0 Laminin Domain II PhageMin_Tail PF10145.4 ETO09483.1 - 0.18 11.4 0.9 0.95 9.0 0.1 2.3 2 1 0 2 2 1 0 Phage-related minor tail protein HAUS-augmin3 PF14932.1 ETO09483.1 - 1.1 8.3 18.2 2 7.5 2.5 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 MRP-S27 PF10037.4 ETO09483.1 - 1.8 7.3 21.1 0.086 11.7 4.8 2.1 1 1 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 Mod_r PF07200.8 ETO09483.1 - 2 8.3 25.8 1.5 8.7 5.1 2.6 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Baculo_PEP_C PF04513.7 ETO09483.1 - 2.3 8.0 8.2 2.1 8.1 2.8 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.4 ETO09483.1 - 3 8.0 19.5 0.056 13.5 4.8 3.0 2 2 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1515 PF07439.6 ETO09483.1 - 3.3 7.5 9.4 0.2 11.4 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Phage_GPO PF05929.6 ETO09483.1 - 3.4 6.8 12.4 2.5 7.2 1.8 2.2 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Lebercilin PF15619.1 ETO09483.1 - 3.8 6.8 32.1 1.1 8.6 8.0 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Bap31 PF05529.7 ETO09483.1 - 4.3 6.7 19.9 0.27 10.6 4.6 2.5 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Cupin_4 PF08007.7 ETO09483.1 - 4.5 6.4 9.2 0.59 9.3 2.4 1.9 1 1 1 2 2 2 0 Cupin superfamily protein OmpH PF03938.9 ETO09483.1 - 4.8 7.0 23.6 0.086 12.7 3.9 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) CDC37_N PF03234.9 ETO09483.1 - 5 7.4 21.0 2 8.7 11.8 2.2 1 1 2 3 3 3 0 Cdc37 N terminal kinase binding COG2 PF06148.6 ETO09483.1 - 5.3 6.9 18.0 0.039 13.8 1.7 2.5 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_MLP1_2 PF07926.7 ETO09483.1 - 5.8 6.6 26.3 0.4 10.4 8.0 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein GBP_C PF02841.9 ETO09483.1 - 8.1 5.5 27.5 1.3 8.1 5.0 2.1 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain YlqD PF11068.3 ETO09483.1 - 8.1 6.4 24.3 5.2 7.1 5.6 2.4 2 0 0 2 2 2 0 YlqD protein DUF4200 PF13863.1 ETO09484.1 - 3.8e-28 97.9 23.2 3.8e-28 97.9 16.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) Ribosomal_L38e PF01781.13 ETO09484.1 - 0.55 10.0 8.9 0.05 13.3 2.3 2.2 2 0 0 2 2 2 0 Ribosomal L38e protein family DUF4045 PF13254.1 ETO09484.1 - 1.4 8.1 12.0 1.7 7.8 8.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Adap_comp_sub PF00928.16 ETO09485.1 - 1.3e-38 132.6 0.1 1.6e-38 132.3 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 ETO09485.1 - 0.0078 15.9 0.1 0.021 14.5 0.0 1.8 2 0 0 2 2 2 1 Clathrin adaptor complex small chain CSD PF00313.17 ETO09486.1 - 0.00017 21.2 8.7 0.048 13.4 0.1 3.9 4 0 0 4 4 4 3 'Cold-shock' DNA-binding domain Ferritin PF00210.19 ETO09488.1 - 0.063 13.0 0.2 0.17 11.6 0.2 1.5 1 1 0 1 1 1 0 Ferritin-like domain STAS PF01740.16 ETO09489.1 - 3.3e-19 68.4 0.0 6e-19 67.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain Sulfate_transp PF00916.15 ETO09489.1 - 0.0011 17.9 0.9 0.0017 17.4 0.6 1.3 1 0 0 1 1 1 1 Sulfate transporter family Zip PF02535.17 ETO09490.1 - 0.4 9.6 6.0 0.45 9.4 4.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2946 PF11162.3 ETO09490.1 - 1.4 9.1 10.3 2 8.6 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) G-alpha PF00503.15 ETO09491.1 - 5e-71 239.4 15.3 6.1e-71 239.1 10.6 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO09491.1 - 5.3e-09 35.5 0.5 5.3e-09 35.5 0.3 2.0 2 1 0 2 2 2 1 ADP-ribosylation factor family CLAMP PF14769.1 ETO09491.1 - 1.3 9.2 6.6 0.81 9.8 0.4 3.3 3 1 1 4 4 4 0 Flagellar C1a complex subunit C1a-32 CPSase_L_D2 PF02786.12 ETO09494.1 - 1.3e-39 135.6 0.0 1.7e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 ETO09494.1 - 1.8e-11 43.9 0.0 3.1e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 ETO09494.1 - 0.00057 19.6 0.0 0.00084 19.1 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 ETO09494.1 - 0.0013 17.5 0.0 0.0016 17.2 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.6 ETO09494.1 - 0.023 14.1 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Biotin_carb_C PF02785.14 ETO09495.1 - 6.9e-20 71.0 0.1 3.1e-17 62.4 0.0 2.5 2 0 0 2 2 2 2 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 ETO09495.1 - 5.3e-18 64.4 1.1 5.3e-18 64.4 0.8 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme HlyD_2 PF12700.2 ETO09495.1 - 3.3e-10 39.6 1.2 2.7e-05 23.4 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 ETO09495.1 - 3.1e-09 36.3 0.3 0.00034 20.2 0.1 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.1 ETO09495.1 - 6.7e-06 26.3 0.2 0.16 12.3 0.0 2.8 3 0 0 3 3 3 2 HlyD family secretion protein YqfD PF06898.6 ETO09495.1 - 0.0042 15.8 1.2 0.017 13.8 0.8 1.8 1 1 1 2 2 2 1 Putative stage IV sporulation protein YqfD GCV_H PF01597.14 ETO09495.1 - 0.0086 15.7 0.2 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 Glycine cleavage H-protein PTS_EIIA_1 PF00358.15 ETO09495.1 - 0.016 14.7 0.3 0.37 10.3 0.0 2.4 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 HlyD PF00529.15 ETO09495.1 - 0.026 13.8 0.1 3.1 7.0 0.1 2.2 2 0 0 2 2 2 0 HlyD family secretion protein RnfC_N PF13375.1 ETO09495.1 - 0.04 13.6 2.0 1 9.0 0.9 2.8 2 1 1 3 3 3 0 RnfC Barrel sandwich hybrid domain Peptidase_M23 PF01551.17 ETO09495.1 - 0.17 11.9 1.0 7.7 6.6 1.1 2.6 2 1 0 2 2 2 0 Peptidase family M23 Glyco_transf_34 PF05637.7 ETO09496.1 - 1.1e-11 44.6 7.0 2e-10 40.5 4.8 2.5 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 ETO09496.1 - 0.0006 19.1 2.2 0.0012 18.1 1.5 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF273 MFS_1 PF07690.11 ETO09497.1 - 0.0041 15.8 15.2 0.005 15.5 10.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily LRR_4 PF12799.2 ETO09498.1 - 1.9e-12 46.5 11.6 7.9e-06 25.3 0.3 3.3 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 ETO09498.1 - 3.1e-11 43.1 1.8 5.8e-11 42.2 1.3 1.4 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 ETO09498.1 - 2.9e-05 23.7 12.8 0.0033 17.1 2.6 3.8 2 1 2 4 4 4 3 Leucine rich repeat LRR_7 PF13504.1 ETO09498.1 - 0.0061 16.5 7.7 3.4 8.2 0.5 5.3 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 ETO09498.1 - 0.0094 15.9 5.0 3.7 7.8 0.1 4.4 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.28 ETO09498.1 - 0.016 15.1 12.8 6.6 7.1 2.3 5.6 5 1 0 5 5 5 0 Leucine Rich Repeat zf-CCCH PF00642.19 ETO09499.1 - 1.5e-08 34.1 15.8 7.1e-06 25.5 1.6 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 ETO09499.1 - 9.1e-07 28.6 0.0 1.5e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO09499.1 - 5.3e-06 25.9 0.0 1.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO09499.1 - 0.053 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Peptidase_M19 PF01244.16 ETO09500.1 - 0.081 11.8 0.1 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) ECH PF00378.15 ETO09502.1 - 3.9e-20 72.0 0.0 5e-20 71.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF4496 PF14908.1 ETO09504.1 - 0.0064 16.3 1.4 0.079 12.8 0.2 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4496) LMBR1 PF04791.11 ETO09505.1 - 0.059 11.9 0.0 0.099 11.2 0.0 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein TFIIA PF03153.8 ETO09505.1 - 4.1 7.2 44.8 7 6.4 31.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PUF PF00806.14 ETO09506.1 - 1.2e-18 65.4 0.7 9.1e-07 28.0 0.0 3.4 3 0 0 3 3 3 3 Pumilio-family RNA binding repeat Phenyl_P_gamma PF09662.5 ETO09506.1 - 0.021 14.4 0.4 1.7 8.3 0.0 3.0 2 1 1 3 3 3 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) TPR_1 PF00515.23 ETO09507.1 - 0.0041 16.6 2.6 0.3 10.7 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat Vwaint PF14624.1 ETO09507.1 - 0.02 14.9 0.1 0.049 13.7 0.0 1.7 1 0 0 1 1 1 0 VWA / Hh protein intein-like TPR_2 PF07719.12 ETO09507.1 - 0.023 14.5 3.7 16 5.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 ETO09507.1 - 0.023 14.3 3.3 4.5 6.9 0.2 3.1 2 1 0 2 2 2 0 TPR repeat PDR_CDR PF06422.7 ETO09507.1 - 1.7 8.3 9.3 1.6 8.4 4.4 2.4 2 1 0 2 2 2 0 CDR ABC transporter YajC PF02699.10 ETO09507.1 - 8.5 6.1 8.1 0.34 10.5 0.5 2.3 2 0 0 2 2 2 0 Preprotein translocase subunit GAT PF03127.9 ETO09508.1 - 0.002 18.0 5.0 0.0078 16.1 1.4 2.3 2 0 0 2 2 2 1 GAT domain SprT-like PF10263.4 ETO09508.1 - 0.038 13.6 1.3 0.07 12.7 0.9 1.5 1 0 0 1 1 1 0 SprT-like family DUF106 PF01956.11 ETO09508.1 - 4.8 6.6 9.9 6.6 6.2 2.6 2.1 2 0 0 2 2 2 0 Integral membrane protein DUF106 Zn-ribbon_8 PF09723.5 ETO09508.1 - 8.8 6.3 11.3 1.3e+02 2.6 7.8 2.5 1 1 0 1 1 1 0 Zinc ribbon domain Myc_N PF01056.13 ETO09509.1 - 0.021 14.0 2.2 0.037 13.1 1.5 1.4 1 0 0 1 1 1 0 Myc amino-terminal region FAM176 PF14851.1 ETO09509.1 - 0.32 10.6 2.5 0.71 9.5 1.7 1.6 1 0 0 1 1 1 0 FAM176 family Spore_coat_CotO PF14153.1 ETO09509.1 - 0.48 9.8 9.7 1 8.8 6.7 1.5 1 0 0 1 1 1 0 Spore coat protein CotO BSP_II PF05432.6 ETO09509.1 - 7.5 5.7 9.4 14 4.8 6.5 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Kinesin PF00225.18 ETO09510.1 - 3.9e-24 84.9 1.9 9.2e-18 64.0 0.4 2.1 1 1 1 2 2 2 2 Kinesin motor domain DUF2443 PF10398.4 ETO09510.1 - 0.019 14.7 0.1 0.047 13.4 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2443) zf-RING_5 PF14634.1 ETO09511.1 - 0.0027 17.3 5.7 0.0027 17.3 4.0 3.3 2 1 0 2 2 2 1 zinc-RING finger domain zf-TRAF PF02176.13 ETO09511.1 - 0.022 15.1 10.1 0.022 15.1 7.0 4.3 2 2 2 4 4 4 0 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 ETO09511.1 - 0.029 14.3 5.6 0.029 14.3 3.9 3.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn-ribbon_8 PF09723.5 ETO09511.1 - 0.97 9.4 10.8 3.9 7.5 1.1 3.9 3 0 0 3 3 3 0 Zinc ribbon domain WD40 PF00400.27 ETO09512.1 - 6.1e-12 44.9 2.0 3.7e-08 32.9 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO09512.1 - 0.0042 15.2 0.1 0.0055 14.9 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO09512.1 - 0.094 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 ETO09513.1 - 1.6e-07 30.9 0.7 4.9e-07 29.3 0.5 1.9 1 0 0 1 1 1 1 WD domain, G-beta repeat Filament PF00038.16 ETO09514.1 - 0.00013 21.5 0.4 0.00013 21.5 0.3 1.8 2 0 0 2 2 2 1 Intermediate filament protein LTD PF00932.14 ETO09514.1 - 0.00019 21.4 0.2 0.00076 19.5 0.0 2.0 2 1 0 2 2 2 1 Lamin Tail Domain DUF1283 PF06932.6 ETO09514.1 - 2.8 8.0 8.1 1.4 8.9 1.5 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1283) HMG14_17 PF01101.13 ETO09514.1 - 4.5 8.0 11.4 8.5 7.1 7.9 1.5 1 0 0 1 1 1 0 HMG14 and HMG17 TPR_11 PF13414.1 ETO09515.1 - 0.00078 19.0 0.4 0.15 11.6 0.1 2.6 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 ETO09515.1 - 0.0038 17.0 2.4 0.61 10.1 0.2 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO09515.1 - 0.012 16.2 0.2 0.063 13.9 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETO09515.1 - 0.056 13.0 1.7 3.6 7.3 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Mito_carr PF00153.22 ETO09516.1 - 2.1e-22 78.6 1.1 1.4e-14 53.5 0.2 2.4 1 1 1 2 2 2 2 Mitochondrial carrier protein zf-H2C2_2 PF13465.1 ETO09517.1 - 1.6e-12 47.0 22.9 1.6e-08 34.4 1.6 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 ETO09517.1 - 5.1e-09 35.9 21.7 0.002 18.3 2.8 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-BED PF02892.10 ETO09517.1 - 2.8e-06 26.9 20.8 0.0091 15.7 2.0 3.8 2 1 1 3 3 3 3 BED zinc finger zf-C2H2_6 PF13912.1 ETO09517.1 - 2.8e-05 23.8 15.0 0.0018 18.0 0.4 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_4 PF13894.1 ETO09517.1 - 3.4e-05 23.8 13.7 0.099 13.0 0.2 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 ETO09517.1 - 0.38 10.9 17.3 5.6 7.2 0.4 3.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-CHCC PF10276.4 ETO09517.1 - 1.1 9.1 9.7 1.4 8.8 0.3 3.4 3 0 0 3 3 3 0 Zinc-finger domain DZR PF12773.2 ETO09517.1 - 1.4 8.7 5.8 19 5.1 4.0 2.7 1 1 0 1 1 1 0 Double zinc ribbon AAA PF00004.24 ETO09518.1 - 2.1e-43 147.6 0.1 5.1e-43 146.4 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 ETO09518.1 - 1.2e-07 31.7 0.1 3.6e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 ETO09518.1 - 1.6e-06 28.2 0.1 0.00014 22.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 ETO09518.1 - 1.3e-05 24.9 0.1 5.8e-05 22.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 ETO09518.1 - 1.5e-05 25.0 0.0 8.2e-05 22.6 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 ETO09518.1 - 2.8e-05 23.1 0.0 7.9e-05 21.6 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 ETO09518.1 - 4.3e-05 22.6 0.0 9.3e-05 21.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 ETO09518.1 - 0.00028 20.3 0.1 0.0007 19.0 0.1 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 ETO09518.1 - 0.00034 20.5 0.1 0.00092 19.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 ETO09518.1 - 0.00063 19.4 0.3 0.0013 18.4 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 ETO09518.1 - 0.00077 19.7 0.4 0.019 15.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ETO09518.1 - 0.00079 20.2 0.2 0.0025 18.5 0.1 1.9 1 1 0 2 2 1 1 AAA domain AAA_25 PF13481.1 ETO09518.1 - 0.0012 18.3 0.3 0.03 13.7 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.1 ETO09518.1 - 0.0025 17.7 0.1 0.0052 16.7 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 ETO09518.1 - 0.0028 17.5 0.0 0.0052 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 ETO09518.1 - 0.0055 16.3 0.0 0.1 12.2 0.0 2.3 1 1 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 ETO09518.1 - 0.006 16.7 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 RNA helicase PhoH PF02562.11 ETO09518.1 - 0.0074 15.5 0.2 0.052 12.7 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 ETO09518.1 - 0.0092 15.1 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 ETO09518.1 - 0.011 14.8 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin KaiC PF06745.8 ETO09518.1 - 0.012 14.7 0.1 0.31 10.1 0.0 2.3 1 1 0 2 2 2 0 KaiC AAA_24 PF13479.1 ETO09518.1 - 0.013 15.1 0.2 0.032 13.7 0.2 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 ETO09518.1 - 0.016 13.9 0.0 0.03 13.0 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus DUF1216 PF06746.6 ETO09518.1 - 0.024 14.4 3.9 0.04 13.6 2.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1216) AAA_3 PF07726.6 ETO09518.1 - 0.027 14.0 0.0 0.087 12.4 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 ETO09518.1 - 0.03 14.3 0.0 0.11 12.5 0.0 2.0 2 1 0 2 2 1 0 Sigma-54 interaction domain AAA_30 PF13604.1 ETO09518.1 - 0.055 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 ETO09518.1 - 0.092 12.4 1.2 1.6 8.3 0.0 3.0 2 1 1 3 3 3 0 NTPase Parvo_NS1 PF01057.12 ETO09518.1 - 0.092 11.6 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 LRR_6 PF13516.1 ETO09519.1 - 2.9e-09 36.0 27.2 0.035 14.1 0.0 9.0 9 0 0 9 9 9 3 Leucine Rich repeat NifU_N PF01592.11 ETO09519.1 - 0.0011 18.8 0.0 0.0024 17.8 0.0 1.5 1 0 0 1 1 1 1 NifU-like N terminal domain LRR_4 PF12799.2 ETO09519.1 - 0.02 14.5 9.3 1.6 8.4 0.8 4.9 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETO09519.1 - 0.029 14.3 10.2 41 4.7 0.0 6.6 7 0 0 7 7 7 0 Leucine Rich Repeat ABC1 PF03109.11 ETO09521.1 - 1.7e-11 44.0 0.0 3.3e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.20 ETO09522.1 - 0.0052 15.9 0.0 0.0075 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF3287 PF11690.3 ETO09523.1 - 4.7 7.3 8.7 5.1 7.1 5.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) PrgI PF12666.2 ETO09524.1 - 0.014 15.5 0.6 0.067 13.3 0.0 2.2 2 0 0 2 2 2 0 PrgI family protein Ras PF00071.17 ETO09525.1 - 7.7e-10 38.3 0.4 7.7e-10 38.3 0.3 1.8 3 0 0 3 3 3 1 Ras family GTP_EFTU PF00009.22 ETO09525.1 - 0.0028 17.0 0.2 0.0072 15.7 0.1 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.16 ETO09525.1 - 0.0054 16.0 0.2 0.009 15.2 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family RhoGEF PF00621.15 ETO09526.1 - 1.3e-15 57.7 14.1 6.7e-15 55.4 9.8 2.2 1 1 0 1 1 1 1 RhoGEF domain DUF3911 PF13050.1 ETO09526.1 - 1.1 9.4 4.2 0.58 10.3 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3911) PH PF00169.24 ETO09528.1 - 1.5e-05 25.1 1.1 0.0017 18.5 0.2 3.4 2 1 0 2 2 2 1 PH domain Atrophin-1 PF03154.10 ETO09528.1 - 2.4e-05 22.7 6.2 2.4e-05 22.7 4.3 2.2 3 0 0 3 3 3 1 Atrophin-1 family Hist_deacetyl PF00850.14 ETO09529.1 - 8.6e-22 77.8 0.0 1.2e-21 77.3 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain ATG27 PF09451.5 ETO09530.1 - 0.0072 15.5 4.7 0.023 13.9 3.3 2.0 1 1 0 1 1 1 1 Autophagy-related protein 27 Tetraspannin PF00335.15 ETO09530.1 - 0.023 13.9 0.0 0.049 12.8 0.0 1.5 1 1 0 1 1 1 0 Tetraspanin family DUF3753 PF12575.3 ETO09530.1 - 0.055 13.2 4.6 0.19 11.5 3.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) DUF3899 PF13038.1 ETO09530.1 - 0.39 10.9 2.9 0.41 10.8 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3899) TFIIA PF03153.8 ETO09530.1 - 1.3 8.8 19.9 0.3 10.9 1.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2951 PF11166.3 ETO09530.1 - 4 7.3 11.2 3.4 7.5 5.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) Adap_comp_sub PF00928.16 ETO09531.1 - 1.6e-28 99.5 0.0 2.5e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Longin PF13774.1 ETO09531.1 - 0.043 13.3 0.4 0.14 11.7 0.1 2.0 2 0 0 2 2 2 0 Regulated-SNARE-like domain Ribosomal_L13 PF00572.13 ETO09531.1 - 0.063 13.3 0.1 0.12 12.4 0.1 1.5 1 1 0 1 1 1 0 Ribosomal protein L13 Proteasom_PSMB PF10508.4 ETO09532.1 - 7.4e-17 60.7 1.0 1.1e-16 60.2 0.7 1.3 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit Sec7_N PF12783.2 ETO09533.1 - 1.1e-11 44.4 0.1 2.8e-11 43.1 0.0 1.8 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Actin PF00022.14 ETO09534.1 - 1.1e-119 399.3 0.0 1.3e-119 399.1 0.0 1.0 1 0 0 1 1 1 1 Actin SPX PF03105.14 ETO09535.1 - 5.8e-07 29.5 15.4 1.1e-06 28.6 10.7 1.4 1 1 0 1 1 1 1 SPX domain PBC PF03792.8 ETO09535.1 - 0.0046 16.6 6.5 0.0079 15.9 3.5 1.8 1 1 1 2 2 2 1 PBC domain GIDA PF01134.17 ETO09535.1 - 0.06 12.2 4.3 0.073 11.9 3.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF3038 PF11237.3 ETO09535.1 - 0.065 13.0 1.3 0.1 12.3 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) DUF3834 PF12916.2 ETO09535.1 - 0.079 11.9 0.4 0.27 10.1 0.0 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF3834) RNA_pol_Rpa2_4 PF06883.7 ETO09535.1 - 0.15 12.0 0.1 0.67 9.9 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase I, Rpa2 specific domain RuBisCO_small PF00101.15 ETO09535.1 - 0.18 11.6 3.8 0.13 12.0 0.4 2.1 1 1 1 2 2 2 0 Ribulose bisphosphate carboxylase, small chain DUF1788 PF08747.6 ETO09535.1 - 0.19 11.5 3.2 0.14 11.9 0.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1788) PRP1_N PF06424.7 ETO09535.1 - 0.88 9.8 5.1 1.2 9.4 3.6 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DUF3808 PF10300.4 ETO09535.1 - 6.1 5.2 10.9 0.84 8.1 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3808) GPI2 PF06432.6 ETO09537.1 - 2.5e-31 109.0 17.7 3.1e-31 108.7 12.3 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase PT PF04886.7 ETO09539.1 - 0.00018 20.7 60.4 4.8 6.5 14.9 4.6 1 1 1 2 2 2 1 PT repeat Kelch_6 PF13964.1 ETO09539.1 - 0.00024 21.1 17.8 0.0017 18.4 0.9 4.6 4 1 1 5 5 5 2 Kelch motif TMEM154 PF15102.1 ETO09539.1 - 0.00034 20.3 0.1 0.00034 20.3 0.1 2.2 2 0 0 2 2 2 1 TMEM154 protein family Kelch_1 PF01344.20 ETO09539.1 - 0.00093 18.6 10.6 0.0018 17.7 0.8 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 ETO09539.1 - 0.0048 16.6 2.1 0.046 13.4 0.2 2.7 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.1 ETO09539.1 - 0.0082 16.0 3.4 0.0082 16.0 2.4 2.3 2 0 0 2 2 2 1 Kelch motif DUF912 PF06024.7 ETO09539.1 - 0.14 12.1 0.0 0.14 12.1 0.0 3.7 4 0 0 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Kelch_4 PF13418.1 ETO09539.1 - 0.34 10.7 8.5 0.043 13.5 0.4 3.3 3 0 0 3 3 3 0 Galactose oxidase, central domain SURF2 PF05477.6 ETO09540.1 - 0.002 17.3 20.1 0.0038 16.3 13.9 1.4 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) CENP-T PF15511.1 ETO09540.1 - 0.22 10.7 14.1 0.32 10.1 9.8 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 ETO09540.1 - 0.26 9.1 28.4 0.38 8.6 19.7 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 ETO09540.1 - 0.32 10.2 28.5 0.53 9.5 19.8 1.3 1 0 0 1 1 1 0 SDA1 Ndc1_Nup PF09531.5 ETO09540.1 - 0.48 8.7 2.3 0.9 7.8 1.6 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Daxx PF03344.10 ETO09540.1 - 0.83 8.0 27.4 1.2 7.5 19.0 1.1 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 ETO09540.1 - 5.8 5.8 30.0 8.9 5.2 20.8 1.2 1 0 0 1 1 1 0 BUD22 Nuf2 PF03800.9 ETO09541.1 - 0.072 13.0 1.4 0.14 12.1 0.1 1.9 2 0 0 2 2 2 0 Nuf2 family Nop16 PF09420.5 ETO09541.1 - 0.1 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 SPRY PF00622.23 ETO09543.1 - 7e-09 35.8 0.8 1.8e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 SPRY domain Rtf2 PF04641.7 ETO09544.1 - 2.6e-43 148.0 17.5 3.8e-42 144.2 8.4 2.0 1 1 1 2 2 2 2 Rtf2 RING-finger zf-RING_UBOX PF13445.1 ETO09544.1 - 0.0064 16.1 0.5 0.024 14.3 0.3 2.2 1 1 0 1 1 1 1 RING-type zinc-finger MRP-S26 PF14943.1 ETO09544.1 - 0.038 13.5 15.9 0.091 12.3 11.0 1.6 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Vfa1 PF08432.5 ETO09544.1 - 0.25 11.3 18.7 0.49 10.3 13.0 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Tom37_C PF11801.3 ETO09544.1 - 0.54 10.1 10.5 0.87 9.4 7.3 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain DDHD PF02862.12 ETO09544.1 - 1.4 8.6 12.4 2.1 8.1 8.6 1.3 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.9 ETO09544.1 - 1.9 6.4 15.6 2.6 5.9 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein RP-C_C PF11800.3 ETO09544.1 - 9.6 5.8 8.6 14 5.3 6.0 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF1993 PF09351.5 ETO09545.1 - 0.014 15.3 0.8 0.016 15.1 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) LUC7 PF03194.10 ETO09545.1 - 0.027 14.0 7.8 0.028 13.9 5.4 1.0 1 0 0 1 1 1 0 LUC7 N_terminus Muted PF14942.1 ETO09545.1 - 0.028 14.2 8.3 0.033 14.0 5.8 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein AAA_13 PF13166.1 ETO09545.1 - 0.032 12.7 8.2 0.034 12.6 5.7 1.0 1 0 0 1 1 1 0 AAA domain FliD_C PF07195.7 ETO09545.1 - 0.036 13.3 4.1 0.044 13.0 2.8 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Spc7 PF08317.6 ETO09545.1 - 0.12 11.0 10.9 0.13 10.9 7.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein LIM_bind PF01803.11 ETO09545.1 - 0.13 11.3 3.2 0.13 11.3 2.2 1.1 1 0 0 1 1 1 0 LIM-domain binding protein CALCOCO1 PF07888.6 ETO09545.1 - 0.15 10.3 7.7 0.16 10.2 5.3 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like V_ATPase_I PF01496.14 ETO09545.1 - 0.22 9.3 5.5 0.2 9.4 3.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lyase_8_N PF08124.6 ETO09545.1 - 0.22 10.3 3.9 0.24 10.2 2.7 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain Phage_GPO PF05929.6 ETO09545.1 - 0.26 10.5 5.0 0.28 10.3 3.5 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase GP41 PF00517.12 ETO09545.1 - 0.26 10.8 5.3 0.32 10.5 3.7 1.1 1 0 0 1 1 1 0 Retroviral envelope protein HAUS6_N PF14661.1 ETO09545.1 - 0.38 10.0 8.5 0.45 9.8 5.9 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Fib_alpha PF08702.5 ETO09545.1 - 0.44 10.6 10.5 0.55 10.3 7.3 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family APG6 PF04111.7 ETO09545.1 - 0.69 8.9 9.7 0.76 8.7 6.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2935 PF11155.3 ETO09545.1 - 0.79 9.8 5.4 1.2 9.2 3.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) DUF4078 PF13300.1 ETO09545.1 - 0.8 9.8 13.2 3.6 7.7 1.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4078) DUF972 PF06156.8 ETO09545.1 - 0.82 10.0 13.2 3.5 8.0 8.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) FAD-SLDH PF12318.3 ETO09545.1 - 1 9.0 4.9 2 8.1 1.7 1.9 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase Cyclin_C PF02984.14 ETO09545.1 - 1.6 8.6 4.5 3.8 7.4 3.0 1.6 1 1 1 2 2 2 0 Cyclin, C-terminal domain DUF755 PF05501.6 ETO09545.1 - 1.7 8.6 16.2 2.8 7.9 11.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF755) TMPIT PF07851.8 ETO09545.1 - 2 7.3 8.0 2.2 7.2 5.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein DOR PF14839.1 ETO09545.1 - 2.2 7.9 7.8 2.8 7.6 5.4 1.2 1 0 0 1 1 1 0 DOR family Fzo_mitofusin PF04799.8 ETO09545.1 - 2.2 7.6 7.5 3.1 7.1 5.2 1.3 1 1 0 1 1 1 0 fzo-like conserved region Atg14 PF10186.4 ETO09545.1 - 2.9 6.7 12.5 3.4 6.5 8.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF106 PF01956.11 ETO09545.1 - 3.7 7.0 8.6 2.9 7.3 5.2 1.3 1 1 0 1 1 1 0 Integral membrane protein DUF106 Peptidase_S49_N PF08496.5 ETO09545.1 - 3.7 7.3 7.9 4.7 6.9 5.5 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PRKCSH-like PF12999.2 ETO09545.1 - 4 6.9 7.9 4.9 6.6 5.5 1.2 1 0 0 1 1 1 0 Glucosidase II beta subunit-like Seryl_tRNA_N PF02403.17 ETO09545.1 - 6.3 6.8 18.3 2.9 7.9 5.7 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Pkinase PF00069.20 ETO09546.1 - 4.5e-14 52.2 0.0 8.5e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO09546.1 - 0.0013 17.8 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Neur_chan_memb PF02932.11 ETO09546.1 - 0.03 14.2 0.2 0.054 13.3 0.2 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AAA PF00004.24 ETO09547.1 - 1.3e-43 148.3 0.0 1.9e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETO09547.1 - 2.2e-06 27.4 0.0 1.3e-05 24.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 ETO09547.1 - 3.6e-06 26.9 0.0 5.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 ETO09547.1 - 1.5e-05 25.1 0.0 0.0026 17.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 ETO09547.1 - 3.5e-05 23.7 0.0 6.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETO09547.1 - 3.8e-05 23.7 0.1 0.0016 18.4 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 ETO09547.1 - 4.1e-05 23.4 0.0 7.1e-05 22.7 0.0 1.3 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 ETO09547.1 - 7.5e-05 21.8 0.1 0.00028 19.9 0.0 1.8 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 ETO09547.1 - 0.00017 22.3 0.0 0.00032 21.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 ETO09547.1 - 0.00026 20.6 0.0 0.047 13.3 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 ETO09547.1 - 0.00051 19.7 0.1 0.0025 17.5 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 ETO09547.1 - 0.0026 17.2 0.1 0.47 9.8 0.0 2.1 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 ETO09547.1 - 0.0029 16.7 0.1 0.0064 15.6 0.1 1.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 ETO09547.1 - 0.0037 16.6 0.0 0.0098 15.3 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.17 ETO09547.1 - 0.0041 17.2 0.0 0.0072 16.4 0.0 1.5 1 1 0 1 1 1 1 RNA helicase Arch_ATPase PF01637.13 ETO09547.1 - 0.0077 15.9 0.0 0.66 9.6 0.0 2.1 1 1 1 2 2 2 1 Archaeal ATPase Zeta_toxin PF06414.7 ETO09547.1 - 0.011 14.7 0.0 0.015 14.3 0.0 1.4 1 1 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 ETO09547.1 - 0.017 15.4 0.0 0.038 14.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain Cytidylate_kin2 PF13189.1 ETO09547.1 - 0.023 14.6 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase-like family Viral_helicase1 PF01443.13 ETO09547.1 - 0.033 13.6 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.1 ETO09547.1 - 0.034 14.1 0.0 0.043 13.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.10 ETO09547.1 - 0.037 12.7 0.0 0.042 12.5 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Sigma54_activat PF00158.21 ETO09547.1 - 0.042 13.3 0.0 0.5 9.8 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.8 ETO09547.1 - 0.075 11.7 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus DUF2075 PF09848.4 ETO09547.1 - 0.12 11.3 0.0 0.25 10.2 0.0 1.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 ETO09547.1 - 0.14 11.0 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain U-box PF04564.10 ETO09548.1 - 6.6e-17 61.2 0.0 1.3e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 U-box domain SAM_1 PF00536.25 ETO09548.1 - 2.8e-08 33.8 1.0 4.4e-08 33.1 0.3 1.6 2 0 0 2 2 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO09548.1 - 4.2e-06 26.5 0.9 8.8e-06 25.4 0.2 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Rtf2 PF04641.7 ETO09548.1 - 5.5e-06 25.7 2.0 6.9e-06 25.4 1.4 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger Vfa1 PF08432.5 ETO09548.1 - 0.0019 18.2 9.1 0.0022 18.0 6.3 1.2 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Peptidase_M14 PF00246.19 ETO09548.1 - 0.0077 15.8 0.4 0.01 15.4 0.3 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase CobT PF06213.7 ETO09548.1 - 0.018 14.2 10.8 0.024 13.8 7.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Glyoxalase PF00903.20 ETO09548.1 - 0.023 14.6 0.1 0.028 14.3 0.1 1.2 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Packaging_FI PF14000.1 ETO09548.1 - 0.025 14.7 5.0 0.04 14.1 3.4 1.3 1 0 0 1 1 1 0 DNA packaging protein FI Astro_capsid PF03115.9 ETO09548.1 - 0.033 12.4 5.2 0.036 12.3 3.6 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor zf-Nse PF11789.3 ETO09548.1 - 0.079 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF2457 PF10446.4 ETO09548.1 - 0.1 11.3 20.7 0.13 10.9 14.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FLO_LFY PF01698.11 ETO09548.1 - 0.11 11.3 5.7 0.14 11.0 4.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Anoctamin PF04547.7 ETO09548.1 - 0.19 10.3 0.4 0.22 10.1 0.3 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel PRTP PF01366.13 ETO09548.1 - 0.23 9.4 5.6 0.28 9.1 3.9 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein CDC45 PF02724.9 ETO09548.1 - 0.38 8.7 11.5 0.46 8.4 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein BTV_NS2 PF04514.7 ETO09548.1 - 0.55 9.0 8.0 0.68 8.7 5.6 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF1510 PF07423.6 ETO09548.1 - 0.97 8.7 14.6 1.3 8.3 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Tim54 PF11711.3 ETO09548.1 - 1.6 7.2 7.7 2.4 6.6 5.2 1.3 1 1 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FAM60A PF15396.1 ETO09548.1 - 6.7 6.3 7.5 8.4 6.0 5.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A PBP1_TM PF14812.1 ETO09548.1 - 6.9 7.0 16.3 14 6.0 11.3 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal uDENN PF03456.13 ETO09549.1 - 1.2e-07 31.5 0.6 2.1e-06 27.6 0.4 2.5 1 1 0 1 1 1 1 uDENN domain DENN PF02141.16 ETO09549.1 - 0.014 15.1 0.1 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 DENN (AEX-3) domain RNA_pol_Rpc34 PF05158.7 ETO09550.1 - 1.5e-24 86.8 7.5 3.3e-13 49.5 3.2 3.1 2 1 0 2 2 2 2 RNA polymerase Rpc34 subunit Rio2_N PF09202.6 ETO09550.1 - 0.039 14.0 1.4 0.29 11.2 0.3 2.4 2 0 0 2 2 2 0 Rio2, N-terminal DUF3687 PF12459.3 ETO09550.1 - 0.4 9.9 7.0 0.33 10.2 3.2 2.0 1 1 1 2 2 2 0 D-Ala-teichoic acid biosynthesis protein Helicase_C PF00271.26 ETO09551.1 - 4.5e-21 74.5 0.5 9.7e-21 73.4 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 ETO09551.1 - 0.003 17.5 0.0 0.0062 16.5 0.0 1.4 1 1 0 1 1 1 1 Helicase C-terminal domain UPF0262 PF06793.7 ETO09551.1 - 0.072 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) Mit_proteolip PF08039.6 ETO09551.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial proteolipid DUF285 PF03382.9 ETO09552.1 - 0.18 11.4 4.9 0.41 10.2 3.4 1.5 1 1 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 U-box PF04564.10 ETO09553.1 - 2.8e-27 94.4 0.5 4.1e-27 93.9 0.4 1.3 1 0 0 1 1 1 1 U-box domain DUF1235 PF06822.7 ETO09553.1 - 0.03 13.2 0.2 0.05 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1235) SPX PF03105.14 ETO09555.1 - 0.24 11.1 19.9 0.81 9.4 0.2 2.2 2 0 0 2 2 2 0 SPX domain SprA-related PF12118.3 ETO09555.1 - 2 7.6 11.1 3.6 6.8 7.7 1.4 1 0 0 1 1 1 0 SprA-related family Utp14 PF04615.8 ETO09555.1 - 2.7 6.0 9.4 4.3 5.3 6.5 1.2 1 0 0 1 1 1 0 Utp14 protein DUF2407_C PF13373.1 ETO09555.1 - 4.3 7.2 9.9 17 5.3 0.0 2.8 3 0 0 3 3 3 0 DUF2407 C-terminal domain Raftlin PF15250.1 ETO09555.1 - 8.5 4.7 7.0 14 4.0 4.8 1.3 1 0 0 1 1 1 0 Raftlin DUF912 PF06024.7 ETO09555.1 - 9.5 6.3 26.2 8.9 6.4 11.5 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3089 PF11288.3 ETO09556.1 - 2.1e-31 108.7 0.0 3.4e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) Pkinase PF00069.20 ETO09557.1 - 8.1e-25 87.4 3.6 3.1e-12 46.2 0.0 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO09557.1 - 2.5e-15 56.2 0.0 4.5e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETO09557.1 - 2.9e-06 27.2 0.1 4.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Thioredoxin_2 PF13098.1 ETO09557.1 - 0.02 15.1 0.8 0.046 13.9 0.6 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain CD99L2 PF12301.3 ETO09557.1 - 4.8 6.8 8.4 0.18 11.4 0.9 1.9 2 0 0 2 2 2 0 CD99 antigen like protein 2 Ank_2 PF12796.2 ETO09558.1 - 2.4e-29 101.4 0.4 9.3e-15 54.7 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETO09558.1 - 4.9e-23 79.7 0.9 9.7e-08 31.4 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 ETO09558.1 - 3.1e-19 68.5 2.5 1.4e-10 41.0 0.4 3.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO09558.1 - 3.2e-18 65.7 1.1 1.8e-07 31.5 0.3 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO09558.1 - 1.6e-13 49.4 1.8 0.00017 21.5 0.1 5.0 5 0 0 5 5 5 2 Ankyrin repeat DUF249 PF03158.8 ETO09558.1 - 0.02 14.4 0.3 0.2 11.2 0.1 2.3 1 1 1 2 2 2 0 Multigene family 530 protein DUF2208 PF09973.4 ETO09558.1 - 0.18 11.0 2.8 0.13 11.4 0.3 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Ank_2 PF12796.2 ETO09559.1 - 1.8e-09 37.8 0.0 0.0019 18.5 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO09559.1 - 4.9e-09 36.4 0.0 0.0077 16.7 0.0 4.8 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO09559.1 - 5.1e-05 23.1 0.0 20 5.7 0.0 5.0 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.1 ETO09559.1 - 5.1e-05 23.3 0.0 0.24 11.7 0.0 4.3 4 2 1 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.25 ETO09559.1 - 0.0016 18.1 0.0 20 5.2 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat WSK PF03832.8 ETO09561.1 - 0.01 15.1 0.7 0.029 13.7 0.5 1.8 1 0 0 1 1 1 0 WSK motif DUF1675 PF07897.6 ETO09561.1 - 1.1 9.0 11.5 1.3 8.7 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF4407 PF14362.1 ETO09561.1 - 3.6 6.4 10.1 5.1 5.9 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EF-hand_1 PF00036.27 ETO09562.1 - 1.5e-30 102.1 16.9 4.5e-10 38.0 0.1 4.9 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 ETO09562.1 - 6.2e-30 103.1 4.1 2.5e-17 62.7 0.6 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 ETO09562.1 - 1.3e-28 98.3 8.9 1e-13 50.6 0.1 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 ETO09562.1 - 1.3e-21 74.5 11.1 3.7e-09 35.6 0.0 5.2 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.1 ETO09562.1 - 1.3e-19 68.6 8.9 3.8e-07 29.1 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 ETO09562.1 - 2.3e-10 40.2 0.1 3.7e-06 26.7 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 ETO09562.1 - 2.5e-06 27.1 1.5 0.022 14.4 0.1 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.8 ETO09562.1 - 5.8e-06 25.8 0.1 0.34 10.5 0.0 3.1 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) SPARC_Ca_bdg PF10591.4 ETO09562.1 - 5.9e-05 23.0 0.0 0.11 12.5 0.0 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.5 ETO09562.1 - 0.00046 20.0 0.1 0.0024 17.8 0.0 2.2 2 0 0 2 2 2 1 Ca2+ insensitive EF hand RNA_pol_Rpb4 PF03874.11 ETO09562.1 - 0.0031 17.5 1.0 1.2 9.2 0.1 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb4 DUF3349 PF11829.3 ETO09562.1 - 0.01 16.2 0.4 11 6.5 0.0 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF3349) Poly_export PF02563.11 ETO09562.1 - 0.018 14.7 0.1 1.2 8.9 0.0 2.9 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein TerB PF05099.8 ETO09562.1 - 0.019 14.7 0.2 0.22 11.2 0.0 2.2 1 1 1 2 2 2 0 Tellurite resistance protein TerB Tenui_NCP PF04876.7 ETO09562.1 - 0.024 14.1 0.1 0.048 13.2 0.1 1.7 1 1 0 1 1 1 0 Tenuivirus major non-capsid protein Imm39 PF15600.1 ETO09562.1 - 0.044 13.6 0.4 0.11 12.3 0.1 1.7 1 1 1 2 2 2 0 Immunity protein 39 LNS2 PF08235.8 ETO09562.1 - 0.11 12.0 0.1 0.66 9.5 0.0 2.0 1 1 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) DUF1103 PF06513.6 ETO09562.1 - 0.19 11.0 5.1 0.28 10.5 3.3 1.4 1 1 0 1 1 1 0 Repeat of unknown function (DUF1103) PB1 PF00564.19 ETO09562.1 - 0.51 10.0 2.4 14 5.4 0.0 3.1 2 1 1 3 3 3 0 PB1 domain Glyco_hydro_3_C PF01915.17 ETO09563.1 - 1e-11 44.8 2.7 6.4e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETO09563.1 - 6.7e-11 41.9 0.3 1.5e-10 40.8 0.2 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF11 PF01345.13 ETO09563.1 - 2.3e-05 24.3 1.5 2.3e-05 24.3 1.0 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF11 PAN_4 PF14295.1 ETO09563.1 - 5.9e-05 22.6 5.5 0.00015 21.4 3.8 1.7 1 0 0 1 1 1 1 PAN domain CARDB PF07705.6 ETO09563.1 - 0.14 12.1 2.4 0.15 12.1 0.1 2.0 2 0 0 2 2 2 0 CARDB WD40 PF00400.27 ETO09565.1 - 5.1e-83 270.2 19.7 2.9e-13 49.1 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO09565.1 - 3.4e-09 35.4 5.5 0.26 9.3 0.1 5.6 1 1 3 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO09565.1 - 0.00017 20.4 9.5 0.31 9.7 0.9 4.1 2 1 2 4 4 4 3 Nup133 N terminal like PQQ_2 PF13360.1 ETO09565.1 - 0.00047 19.6 0.1 0.016 14.6 0.1 2.4 1 1 1 2 2 2 2 PQQ-like domain PD40 PF07676.7 ETO09565.1 - 0.0011 18.5 7.3 3.7 7.3 0.0 5.7 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO09565.1 - 0.0033 15.7 1.6 0.071 11.4 0.0 3.0 2 1 1 3 3 3 1 Cytochrome D1 heme domain DUF1652 PF07865.6 ETO09565.1 - 0.0037 16.8 0.0 0.36 10.4 0.0 3.7 4 0 0 4 4 4 1 Protein of unknown function (DUF1652) Proteasome_A_N PF10584.4 ETO09565.1 - 0.0081 15.4 0.1 2.1 7.7 0.0 3.9 4 0 0 4 4 4 1 Proteasome subunit A N-terminal signature Nbas_N PF15492.1 ETO09565.1 - 0.011 14.7 2.0 4.3 6.3 0.1 3.7 1 1 4 5 5 5 0 Neuroblastoma-amplified sequence, N terminal NodS PF05401.6 ETO09565.1 - 0.017 14.4 0.3 2.2 7.6 0.0 3.3 3 2 1 4 4 4 0 Nodulation protein S (NodS) Hira PF07569.6 ETO09565.1 - 0.019 14.1 1.3 2.3 7.3 0.0 4.1 3 1 2 5 5 5 0 TUP1-like enhancer of split WD40 PF00400.27 ETO09566.1 - 1.8e-55 182.9 14.8 1.1e-10 41.0 0.1 7.4 8 0 0 8 8 8 7 WD domain, G-beta repeat PD40 PF07676.7 ETO09566.1 - 0.00022 20.7 14.8 9.7 5.9 0.0 7.1 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO09566.1 - 0.00027 19.2 4.9 0.14 10.2 0.3 3.9 1 1 1 3 3 3 3 Nucleoporin Nup120/160 DPPIV_N PF00930.16 ETO09566.1 - 0.00083 18.0 0.1 0.12 10.9 0.0 3.4 1 1 3 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nbas_N PF15492.1 ETO09566.1 - 0.0067 15.5 1.6 4.3 6.3 0.0 3.5 1 1 2 3 3 3 1 Neuroblastoma-amplified sequence, N terminal DUF727 PF05303.7 ETO09566.1 - 0.047 13.4 0.1 0.34 10.7 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF727) NodS PF05401.6 ETO09566.1 - 0.081 12.3 0.0 3.4 6.9 0.0 3.0 2 1 1 3 3 3 0 Nodulation protein S (NodS) NHL PF01436.16 ETO09566.1 - 0.084 12.8 0.4 5 7.2 0.0 3.3 3 0 0 3 3 3 0 NHL repeat Proteasome_A_N PF10584.4 ETO09566.1 - 0.35 10.2 7.5 66 2.9 0.0 5.1 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature SYF2 PF08231.7 ETO09567.1 - 0.02 15.0 1.0 0.028 14.5 0.7 1.2 1 0 0 1 1 1 0 SYF2 splicing factor XPG_I_2 PF12813.2 ETO09567.1 - 0.022 14.2 0.1 0.027 13.9 0.0 1.1 1 0 0 1 1 1 0 XPG domain containing DUF2883 PF11097.3 ETO09567.1 - 0.04 14.0 0.1 0.078 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2883) Pribosyltran_N PF13793.1 ETO09567.1 - 0.041 13.6 0.1 0.065 12.9 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain of ribose phosphate pyrophosphokinase Sedlin_N PF04628.8 ETO09567.1 - 0.046 13.5 0.3 0.083 12.7 0.2 1.6 1 1 0 1 1 1 0 Sedlin, N-terminal conserved region RNA_pol_Rpb2_6 PF00562.23 ETO09568.1 - 5.3e-69 232.8 0.0 1.4e-67 228.1 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 Paramyxo_C PF01692.13 ETO09568.1 - 0.26 10.8 1.3 0.45 10.0 0.9 1.4 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c AF-4 PF05110.8 ETO09568.1 - 0.4 8.4 15.2 0.51 8.1 10.6 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RAP1 PF07218.6 ETO09568.1 - 2.4 6.1 6.1 3.2 5.7 4.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SR-25 PF10500.4 ETO09568.1 - 9.9 5.5 19.2 15 4.9 13.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein WD40 PF00400.27 ETO09570.1 - 9.9e-88 285.2 18.1 3.8e-13 48.7 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO09570.1 - 8.8e-09 34.0 8.1 0.017 13.2 0.2 4.4 1 1 3 4 4 4 4 Nucleoporin Nup120/160 PD40 PF07676.7 ETO09570.1 - 1.1e-07 31.3 12.1 1 9.0 0.1 6.8 7 0 0 7 7 7 3 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO09570.1 - 1.8e-07 29.7 1.4 0.0016 16.8 0.1 3.4 2 1 0 3 3 3 3 Cytochrome D1 heme domain DUF1258 PF06869.7 ETO09570.1 - 3e-05 23.2 2.1 0.45 9.5 0.0 3.9 2 2 3 5 5 5 2 Protein of unknown function (DUF1258) Nucleoporin_N PF08801.6 ETO09570.1 - 0.00011 21.0 11.6 0.058 12.1 5.4 4.2 1 1 1 2 2 2 1 Nup133 N terminal like Resistin PF06954.6 ETO09570.1 - 0.055 13.7 0.7 12 6.2 0.0 3.8 2 1 2 4 4 4 0 Resistin Nop10p PF04135.7 ETO09570.1 - 0.1 12.3 0.0 0.47 10.2 0.0 2.1 2 0 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family Ran_BP1 PF00638.13 ETO09571.1 - 2.3e-06 27.6 2.3 2.4e-06 27.5 0.2 1.9 2 0 0 2 2 2 1 RanBP1 domain Ran_BP1 PF00638.13 ETO09572.1 - 4.5e-10 39.6 0.1 7.7e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain zf-rbx1 PF12678.2 ETO09572.1 - 2.2 8.4 7.0 1.3 9.1 0.9 2.5 2 1 1 3 3 3 0 RING-H2 zinc finger Nuc_sug_transp PF04142.10 ETO09575.1 - 1.2e-28 99.8 16.3 4.3e-19 68.5 0.8 2.2 1 1 1 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.15 ETO09575.1 - 2.9e-07 30.5 0.4 2.9e-07 30.5 0.3 4.1 2 1 1 3 3 3 1 EamA-like transporter family EmrE PF13536.1 ETO09575.1 - 0.00016 21.8 0.2 0.00016 21.8 0.2 3.4 3 1 1 4 4 4 1 Multidrug resistance efflux transporter TPT PF03151.11 ETO09575.1 - 0.00068 19.3 17.1 0.35 10.5 0.0 2.7 2 1 0 2 2 2 2 Triose-phosphate Transporter family YjgP_YjgQ PF03739.9 ETO09576.1 - 3 6.5 10.3 1.9 7.1 6.1 1.4 1 1 0 1 1 1 0 Predicted permease YjgP/YjgQ family YIF1 PF03878.10 ETO09577.1 - 0.095 11.8 2.9 0.13 11.3 2.0 1.2 1 0 0 1 1 1 0 YIF1 Pex14_N PF04695.8 ETO09577.1 - 2 8.4 4.9 0.57 10.2 0.7 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase PF00069.20 ETO09578.1 - 4.9e-25 88.1 0.1 5.7e-25 87.9 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO09578.1 - 1.2e-10 40.8 0.3 1.8e-10 40.3 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase IPK PF03770.11 ETO09578.1 - 0.016 14.8 0.1 0.034 13.7 0.0 1.5 2 0 0 2 2 2 0 Inositol polyphosphate kinase DUF4234 PF14018.1 ETO09579.1 - 0.74 9.6 4.7 1.8 8.3 3.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) DUF4131 PF13567.1 ETO09579.1 - 1.3 8.3 3.4 2.1 7.7 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Mnd1 PF03962.10 ETO09580.1 - 0.19 11.3 10.6 0.23 11.0 7.3 1.1 1 0 0 1 1 1 0 Mnd1 family Sec23_trunk PF04811.10 ETO09581.1 - 1.5e-08 34.3 0.2 8.4e-08 31.8 0.1 2.2 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain VWA_2 PF13519.1 ETO09581.1 - 1.7e-05 25.0 0.0 2.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF4642 PF15484.1 ETO09581.1 - 0.53 10.2 6.3 7.1 6.5 1.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4642) zf-Sec23_Sec24 PF04810.10 ETO09582.1 - 6.5e-05 22.4 0.8 0.00016 21.1 0.1 1.9 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger SR-25 PF10500.4 ETO09582.1 - 0.029 13.8 2.8 0.044 13.2 2.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Menin PF05053.8 ETO09582.1 - 0.14 10.3 4.5 0.15 10.1 3.1 1.1 1 0 0 1 1 1 0 Menin Gti1_Pac2 PF09729.4 ETO09582.1 - 0.2 11.4 2.9 0.17 11.7 0.9 1.7 2 0 0 2 2 2 0 Gti1/Pac2 family DUF4551 PF15087.1 ETO09582.1 - 0.3 9.3 4.7 0.37 9.0 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Daxx PF03344.10 ETO09583.1 - 0.21 10.0 19.2 0.34 9.3 13.3 1.2 1 0 0 1 1 1 0 Daxx Family PPP4R2 PF09184.6 ETO09583.1 - 0.56 9.7 20.6 0.99 8.8 14.3 1.3 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.7 ETO09583.1 - 0.97 7.2 19.6 1.4 6.7 13.6 1.1 1 0 0 1 1 1 0 Nop14-like family Ebola_NP PF05505.7 ETO09583.1 - 1.4 6.9 10.8 1.8 6.5 7.5 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein Nucleoplasmin PF03066.10 ETO09583.1 - 2.7 7.4 17.8 6 6.3 12.3 1.6 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 ETO09583.1 - 4.6 5.1 15.0 6.9 4.5 10.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.5 ETO09583.1 - 7.5 6.5 13.1 2.9 7.8 7.0 1.8 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 WD40 PF00400.27 ETO09584.1 - 6.3e-66 216.0 25.8 5.6e-12 45.0 0.2 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO09584.1 - 7.6e-10 37.5 6.8 0.0091 14.1 0.1 5.3 1 1 4 5 5 5 5 Nucleoporin Nup120/160 WD40 PF00400.27 ETO09585.1 - 6.7e-13 47.9 0.6 1.2e-12 47.1 0.4 1.4 1 0 0 1 1 1 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO09585.1 - 0.026 12.6 0.0 0.027 12.6 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 YajC PF02699.10 ETO09587.1 - 0.041 13.5 0.1 0.087 12.5 0.0 1.5 2 0 0 2 2 2 0 Preprotein translocase subunit M11L PF11099.3 ETO09590.1 - 0.0051 16.5 0.2 1.3 8.6 0.0 2.5 2 1 0 2 2 2 2 Apoptosis regulator M11L like HEAT PF02985.17 ETO09590.1 - 0.01 15.8 0.2 0.13 12.4 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat B56 PF01603.15 ETO09590.1 - 0.017 13.7 0.1 0.023 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) RICTOR_V PF14668.1 ETO09590.1 - 0.044 13.7 0.0 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 DUF3385 PF11865.3 ETO09590.1 - 0.078 12.9 1.4 2.4 8.0 0.0 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF3385) HEAT_2 PF13646.1 ETO09590.1 - 0.13 12.5 0.0 0.34 11.2 0.0 1.7 2 0 0 2 2 2 0 HEAT repeats HEAT_2 PF13646.1 ETO09591.1 - 4.4e-10 39.6 0.2 0.017 15.4 0.0 5.4 4 2 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 ETO09591.1 - 7.8e-09 35.7 2.8 1.2 9.6 0.9 6.3 5 1 1 6 6 6 4 HEAT-like repeat HEAT PF02985.17 ETO09591.1 - 4.8e-06 26.2 4.7 0.021 14.8 0.0 6.4 7 0 0 7 7 7 1 HEAT repeat RIX1 PF08167.7 ETO09591.1 - 1.7e-05 24.5 0.1 0.049 13.3 0.0 4.4 4 0 0 4 4 4 1 rRNA processing/ribosome biogenesis DRIM PF07539.7 ETO09591.1 - 0.011 15.0 1.1 0.84 9.0 0.1 3.4 4 0 0 4 4 4 0 Down-regulated in metastasis DUF3385 PF11865.3 ETO09591.1 - 0.014 15.3 3.3 8.6 6.2 0.0 5.0 5 1 0 5 5 5 0 Domain of unknown function (DUF3385) CLASP_N PF12348.3 ETO09591.1 - 0.025 13.9 4.8 0.61 9.4 0.1 4.1 4 1 0 4 4 4 0 CLASP N terminal Arm PF00514.18 ETO09591.1 - 0.085 12.7 2.3 2.3 8.1 0.5 3.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 ETO09591.1 - 0.2 12.2 2.0 1.7 9.3 0.0 3.8 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat YlbD_coat PF14071.1 ETO09591.1 - 6.7 6.7 7.6 3.7 7.6 1.6 2.7 2 0 0 2 2 2 0 Putative coat protein CDC45 PF02724.9 ETO09592.1 - 0.015 13.3 46.1 0.071 11.1 21.5 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF1510 PF07423.6 ETO09592.1 - 2.5 7.4 48.3 3.7 6.8 4.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Pkinase PF00069.20 ETO09593.1 - 1.3e-13 50.7 0.0 1.5e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO09593.1 - 4e-07 29.3 0.0 5.1e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Ras PF00071.17 ETO09594.1 - 2.1e-20 72.7 0.1 2.6e-20 72.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO09594.1 - 0.00099 19.5 0.0 0.0014 19.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO09594.1 - 0.0032 16.7 0.0 0.004 16.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO09594.1 - 0.0058 16.0 0.0 0.0063 15.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain CH PF00307.26 ETO09595.1 - 3.1e-24 85.0 9.1 2.9e-11 43.3 1.3 4.4 4 1 0 4 4 4 3 Calponin homology (CH) domain CAMSAP_CH PF11971.3 ETO09595.1 - 6.8e-07 28.8 1.1 7.4e-06 25.5 0.0 3.2 3 0 0 3 3 3 1 CAMSAP CH domain DUF755 PF05501.6 ETO09596.1 - 0.019 15.0 18.1 0.019 15.0 12.6 3.2 4 1 0 4 4 4 0 Domain of unknown function (DUF755) DUF1730 PF08331.5 ETO09596.1 - 0.058 13.0 0.1 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) Cwf_Cwc_15 PF04889.7 ETO09596.1 - 2 8.0 57.6 0.22 11.1 32.8 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_E_B PF04042.11 ETO09597.1 - 3.3e-21 75.5 0.2 4.6e-21 75.0 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B RabGAP-TBC PF00566.13 ETO09598.1 - 3e-14 52.9 4.8 3e-14 52.9 3.3 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain PH PF00169.24 ETO09598.1 - 2.4e-06 27.6 0.0 5.9e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF615 PF04751.9 ETO09598.1 - 0.0062 16.1 0.1 0.0096 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF615) PH_11 PF15413.1 ETO09598.1 - 0.071 13.3 0.4 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Suc_Fer-like PF06999.7 ETO09601.1 - 0.073 13.0 3.2 0.55 10.2 1.4 2.1 2 0 0 2 2 2 0 Sucrase/ferredoxin-like Kinesin PF00225.18 ETO09602.1 - 3e-32 111.6 0.3 3.6e-32 111.3 0.2 1.0 1 0 0 1 1 1 1 Kinesin motor domain DUF4448 PF14610.1 ETO09603.1 - 0.06 12.8 0.6 0.085 12.3 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) CRT-like PF08627.5 ETO09603.1 - 0.15 12.0 2.7 0.18 11.7 1.1 1.7 1 1 1 2 2 2 0 CRT-like PWWP PF00855.12 ETO09603.1 - 1.2 9.3 3.5 2.2 8.5 2.3 1.8 1 1 0 1 1 1 0 PWWP domain CBP4 PF07960.6 ETO09603.1 - 1.3 8.6 4.9 2.3 7.8 3.4 1.3 1 0 0 1 1 1 0 CBP4 DUF342 PF03961.8 ETO09603.1 - 2.7 6.3 5.7 3.5 5.9 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CENP-I PF07778.6 ETO09604.1 - 0.046 11.9 0.0 0.068 11.3 0.0 1.2 1 0 0 1 1 1 0 Mis6 Macoilin PF09726.4 ETO09604.1 - 6.3 4.9 8.2 7.2 4.7 5.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Atx10homo_assoc PF09759.4 ETO09605.1 - 7.5e-06 25.6 0.3 7.5e-06 25.6 0.2 3.6 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.18 ETO09605.1 - 4.7e-05 23.0 8.5 16 5.5 0.0 8.0 8 0 0 8 8 8 1 Armadillo/beta-catenin-like repeat Proteasom_PSMB PF10508.4 ETO09605.1 - 0.00069 17.9 1.0 0.3 9.3 0.0 5.0 6 0 0 6 6 6 1 Proteasome non-ATPase 26S subunit DUF3361 PF11841.3 ETO09605.1 - 0.054 13.2 0.0 2.7 7.6 0.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) Daxx PF03344.10 ETO09605.1 - 1.7 7.0 22.9 2.7 6.3 15.9 1.2 1 0 0 1 1 1 0 Daxx Family COG7 PF10191.4 ETO09606.1 - 8.7e-19 66.9 2.4 2.2e-17 62.3 1.7 2.0 1 1 0 1 1 1 1 Golgi complex component 7 (COG7) GlutR_dimer PF00745.15 ETO09606.1 - 0.017 15.0 1.1 0.017 15.0 0.8 2.1 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF2509 PF10713.4 ETO09606.1 - 0.058 13.1 0.2 0.14 11.9 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2509) COG7 PF10191.4 ETO09607.1 - 0.00015 19.8 0.1 0.00019 19.4 0.0 1.2 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) COG7 PF10191.4 ETO09608.1 - 1.6e-23 82.6 12.7 2.3e-23 82.0 8.8 1.1 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) IncA PF04156.9 ETO09608.1 - 0.15 11.6 10.2 0.28 10.7 6.9 1.6 1 1 0 1 1 1 0 IncA protein DUF4558 PF15104.1 ETO09608.1 - 0.25 11.2 5.0 0.082 12.8 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4558) AAA_11 PF13086.1 ETO09608.1 - 0.36 10.3 7.6 0.53 9.8 5.2 1.3 1 0 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.7 ETO09608.1 - 0.61 9.8 11.3 2.2 8.1 4.1 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 ETO09608.1 - 3.9 7.8 12.3 1.7 8.9 2.2 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Tim54 PF11711.3 ETO09609.1 - 0.041 12.4 1.0 0.053 12.1 0.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4054 PF13262.1 ETO09609.1 - 0.11 12.7 0.1 0.11 12.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4054) DUF844 PF05815.6 ETO09609.1 - 0.24 10.1 4.7 0.46 9.2 3.3 1.4 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) MSA-2c PF12238.3 ETO09609.1 - 0.98 9.0 9.7 0.038 13.6 2.0 2.0 2 0 0 2 2 2 0 Merozoite surface antigen 2c CorA PF01544.13 ETO09610.1 - 2.2e-07 30.2 1.7 2.9e-07 29.8 1.2 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein GWT1 PF06423.7 ETO09610.1 - 0.014 15.4 0.5 0.018 15.1 0.3 1.2 1 0 0 1 1 1 0 GWT1 Annexin PF00191.15 ETO09611.1 - 2.5e-32 110.5 2.7 2.9e-12 46.3 0.0 4.7 4 0 0 4 4 4 3 Annexin EF-hand_1 PF00036.27 ETO09611.1 - 0.00011 21.1 0.0 0.00043 19.3 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 ETO09611.1 - 0.0016 18.1 0.0 0.011 15.5 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 ETO09611.1 - 0.041 13.2 0.0 0.13 11.6 0.0 2.0 1 0 0 1 1 1 0 EF hand CBS PF00571.23 ETO09612.1 - 2.1e-08 33.8 0.1 0.0028 17.4 0.0 2.3 2 0 0 2 2 2 2 CBS domain THF_DHG_CYH PF00763.18 ETO09612.1 - 0.13 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain SAM_1 PF00536.25 ETO09613.1 - 3.4e-08 33.5 0.8 7.5e-08 32.4 0.1 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO09613.1 - 1.4e-07 31.2 0.3 4.7e-07 29.5 0.1 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 ETO09613.1 - 0.00057 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Tox-REase-7 PF15649.1 ETO09613.1 - 0.54 10.4 7.5 0.44 10.7 0.2 2.7 2 1 0 2 2 2 0 Restriction endonuclease fold toxin 7 fn3 PF00041.16 ETO09615.1 - 1.3e-09 37.9 0.6 0.0035 17.4 0.0 3.5 3 0 0 3 3 3 2 Fibronectin type III domain PDZ PF00595.19 ETO09615.1 - 4.1e-05 23.6 0.0 0.00011 22.2 0.0 1.8 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 ETO09615.1 - 0.00098 18.9 0.2 0.0034 17.2 0.1 1.9 1 0 0 1 1 1 1 PDZ domain Ax_dynein_light PF10211.4 ETO09616.1 - 3.3e-41 141.2 15.1 6.3e-40 137.0 10.4 2.1 1 1 0 1 1 1 1 Axonemal dynein light chain Peptidase_S30 PF01577.11 ETO09616.1 - 0.036 13.4 8.5 0.91 8.8 2.8 2.2 2 0 0 2 2 2 0 Potyvirus P1 protease DUF1007 PF06226.8 ETO09616.1 - 0.064 12.9 1.5 0.062 13.0 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1007) DUF4613 PF15390.1 ETO09616.1 - 0.076 11.1 6.9 0.1 10.7 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF349 PF03993.7 ETO09616.1 - 0.35 11.0 8.2 0.14 12.3 0.6 3.0 3 1 0 3 3 3 0 Domain of Unknown Function (DUF349) Radical_SAM_N PF08497.5 ETO09616.1 - 0.58 9.0 4.4 0.73 8.6 3.0 1.2 1 0 0 1 1 1 0 Radical SAM N-terminal LAMTOR PF15454.1 ETO09616.1 - 1.6 9.0 7.4 6 7.2 0.5 2.9 2 1 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Seryl_tRNA_N PF02403.17 ETO09616.1 - 3 7.9 13.1 0.15 12.0 2.9 2.7 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain WD40 PF00400.27 ETO09617.1 - 2.5e-49 163.4 10.7 6.4e-12 44.8 0.4 8.1 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO09617.1 - 8e-07 27.5 4.4 0.56 8.2 0.0 4.3 1 1 4 5 5 5 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO09617.1 - 1.8e-05 24.3 0.1 0.015 14.7 0.1 2.2 1 1 1 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 ETO09617.1 - 0.0001 21.1 13.8 0.32 9.6 0.1 4.1 2 1 3 5 5 5 3 Nup133 N terminal like PQQ PF01011.16 ETO09617.1 - 0.053 13.0 0.4 14 5.4 0.0 3.6 4 0 0 4 4 4 0 PQQ enzyme repeat Resistin PF06954.6 ETO09617.1 - 0.1 12.8 0.0 12 6.1 0.0 2.5 2 0 0 2 2 2 0 Resistin TPR_12 PF13424.1 ETO09618.1 - 4.2e-44 148.3 11.9 1.8e-18 66.2 1.1 4.4 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO09618.1 - 3.6e-23 80.1 33.5 7.6e-08 31.6 0.9 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO09618.1 - 4.2e-20 71.1 18.8 3.5e-08 32.9 1.3 4.0 4 0 0 4 4 4 3 TPR repeat TPR_2 PF07719.12 ETO09618.1 - 2.6e-16 58.1 24.7 7.5e-05 22.3 0.2 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO09618.1 - 6.9e-16 56.7 31.1 7.1e-06 25.4 0.7 7.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO09618.1 - 2.3e-15 55.9 0.0 0.00072 19.3 0.0 5.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO09618.1 - 4.1e-12 44.9 10.9 0.008 15.9 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO09618.1 - 8.4e-05 22.8 0.0 95 4.0 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.1 ETO09618.1 - 0.00047 20.1 4.5 0.43 10.8 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO09618.1 - 0.00052 20.0 21.0 0.00098 19.2 4.2 4.1 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 ETO09618.1 - 0.0045 16.8 10.5 10 6.0 0.0 5.3 4 1 1 5 5 4 1 MIT (microtubule interacting and transport) domain TPR_16 PF13432.1 ETO09618.1 - 0.013 16.2 2.1 7.9 7.2 0.1 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO09618.1 - 0.27 11.8 10.6 1.7 9.3 0.1 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat WD40 PF00400.27 ETO09619.1 - 2.6e-87 283.8 11.7 1.1e-12 47.2 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO09619.1 - 1.7e-09 36.3 5.0 0.027 12.5 0.1 5.3 1 1 3 4 4 4 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO09619.1 - 1.4e-06 27.9 1.1 0.00039 19.9 0.1 3.1 1 1 2 3 3 3 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO09619.1 - 3.6e-06 25.5 1.5 0.0045 15.3 0.0 2.9 2 1 1 3 3 3 2 Cytochrome D1 heme domain Str_synth PF03088.11 ETO09619.1 - 0.0016 18.4 0.3 3.7 7.6 0.0 4.2 3 1 1 4 4 4 1 Strictosidine synthase PD40 PF07676.7 ETO09619.1 - 0.03 13.9 2.6 23 4.7 0.0 5.1 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Peptidase_C14 PF00656.17 ETO09620.1 - 6.2e-11 42.4 1.3 1.4e-10 41.2 0.9 1.6 1 0 0 1 1 1 1 Caspase domain Kelch_5 PF13854.1 ETO09620.1 - 7.8e-06 25.7 0.6 0.51 10.3 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO09620.1 - 2.2e-05 23.9 7.7 0.00059 19.3 0.1 4.8 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.10 ETO09620.1 - 0.0038 16.9 4.3 0.26 11.1 0.1 4.1 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.1 ETO09620.1 - 0.0098 16.0 0.6 0.72 10.0 0.0 3.5 4 0 0 4 4 4 1 Galactose oxidase, central domain Mcp5_PH PF12814.2 ETO09622.1 - 3.1e-05 23.8 0.1 3.1e-05 23.8 0.1 2.3 3 0 0 3 3 3 1 Meiotic cell cortex C-terminal pleckstrin homology Colicin_C PF12106.3 ETO09623.1 - 0.02 14.4 0.6 0.02 14.4 0.4 2.3 2 0 0 2 2 2 0 Colicin C terminal ribonuclease domain DUF3821 PF12863.2 ETO09624.1 - 0.058 13.0 0.2 0.064 12.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3821) Mcp5_PH PF12814.2 ETO09624.1 - 0.87 9.5 7.6 1.7 8.5 2.2 2.1 1 1 1 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology Peptidase_C97 PF05903.9 ETO09625.1 - 0.014 15.1 0.3 0.049 13.4 0.1 1.9 2 0 0 2 2 2 0 PPPDE putative peptidase domain Apt1 PF10351.4 ETO09625.1 - 0.081 11.7 6.8 0.1 11.4 4.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain TMPIT PF07851.8 ETO09627.1 - 1e-52 179.3 17.4 1.3e-52 178.9 12.1 1.0 1 0 0 1 1 1 1 TMPIT-like protein BBP1_C PF15272.1 ETO09627.1 - 0.0024 17.4 6.0 0.0046 16.5 4.1 1.4 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal ALIX_LYPXL_bnd PF13949.1 ETO09627.1 - 0.0039 16.1 6.4 0.0039 16.1 4.4 1.4 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV V_ATPase_I PF01496.14 ETO09627.1 - 0.044 11.6 9.8 0.16 9.7 5.5 2.3 2 1 0 2 2 2 0 V-type ATPase 116kDa subunit family PhoU_div PF01865.11 ETO09627.1 - 0.072 12.2 1.4 0.12 11.5 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF47 LdpA_C PF12617.3 ETO09627.1 - 0.084 12.1 0.3 0.14 11.4 0.2 1.4 1 0 0 1 1 1 0 Iron-Sulfur binding protein C terminal Hemagglutinin PF00509.13 ETO09627.1 - 0.085 10.9 5.7 0.14 10.3 4.0 1.2 1 0 0 1 1 1 0 Haemagglutinin Prefoldin_2 PF01920.15 ETO09627.1 - 0.087 12.5 10.7 0.46 10.2 0.8 2.5 2 0 0 2 2 2 0 Prefoldin subunit GOLGA2L5 PF15070.1 ETO09627.1 - 0.09 11.2 7.8 1.5 7.2 2.5 2.3 2 1 0 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 Flu_NS2 PF00601.14 ETO09627.1 - 0.11 12.7 0.3 0.11 12.7 0.2 2.6 2 1 1 3 3 2 0 Influenza non-structural protein (NS2) COG2 PF06148.6 ETO09627.1 - 0.21 11.4 4.4 0.11 12.3 0.6 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Sipho_Gp157 PF05565.6 ETO09627.1 - 0.24 10.9 9.9 0.43 10.1 6.9 1.4 1 0 0 1 1 1 0 Siphovirus Gp157 DUF948 PF06103.6 ETO09627.1 - 0.28 11.0 7.5 0.043 13.6 1.4 2.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) MscS_porin PF12795.2 ETO09627.1 - 0.32 10.2 4.9 0.65 9.2 3.4 1.4 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Tweety PF04906.8 ETO09627.1 - 0.48 8.7 6.0 4.2 5.6 1.3 2.2 2 0 0 2 2 2 0 Tweety APG17 PF04108.7 ETO09627.1 - 0.57 8.9 10.7 0.15 10.8 5.0 1.7 2 1 0 2 2 2 0 Autophagy protein Apg17 DUF745 PF05335.8 ETO09627.1 - 0.86 9.0 5.6 1.8 8.0 3.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF1664 PF07889.7 ETO09627.1 - 1.6 8.5 9.0 0.14 11.9 0.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.6 ETO09627.1 - 2 8.3 8.5 3.2 7.7 0.8 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Laminin_II PF06009.7 ETO09627.1 - 2.1 8.1 7.6 1.3 8.8 3.6 1.9 2 1 0 2 2 2 0 Laminin Domain II V-SNARE PF05008.10 ETO09627.1 - 8.2 6.6 10.2 9.2 6.5 0.9 2.6 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus SseC PF04888.7 ETO09627.1 - 8.7 5.5 11.3 1.1 8.5 2.4 2.1 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family HCaRG PF07258.9 ETO09628.1 - 7.1e-19 68.0 1.1 1.2e-18 67.2 0.7 1.4 1 0 0 1 1 1 1 HCaRG protein RNA_ligase PF09414.5 ETO09630.1 - 5.9e-11 42.5 0.0 1.6e-10 41.0 0.0 1.8 1 1 0 1 1 1 1 RNA ligase PCI PF01399.22 ETO09631.1 - 3.7e-06 27.1 0.4 3.7e-06 27.1 0.3 2.5 2 1 0 2 2 2 1 PCI domain Sel1 PF08238.7 ETO09631.1 - 0.03 14.9 0.1 0.35 11.5 0.0 2.8 2 0 0 2 2 2 0 Sel1 repeat SNAP PF14938.1 ETO09631.1 - 0.24 10.5 7.4 0.035 13.2 0.8 2.4 2 1 1 3 3 3 0 Soluble NSF attachment protein, SNAP DUF3429 PF11911.3 ETO09632.1 - 0.052 13.5 0.2 0.052 13.5 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3429) Sulfatase PF00884.18 ETO09633.1 - 9.6e-44 149.7 0.0 2e-43 148.7 0.0 1.6 1 1 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 ETO09633.1 - 7.5e-18 65.0 0.1 1.8e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 ETO09633.1 - 0.0037 16.6 0.0 0.0055 16.0 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4393 PF14337.1 ETO09633.1 - 0.12 11.8 0.0 0.41 10.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4393) Prominin PF05478.6 ETO09635.1 - 4.7e-08 31.0 4.6 1.9e-05 22.4 0.3 2.1 2 0 0 2 2 2 2 Prominin Tweety PF04906.8 ETO09635.1 - 0.0064 14.9 0.1 0.0064 14.9 0.0 2.2 1 1 1 2 2 2 1 Tweety WXG100 PF06013.7 ETO09635.1 - 0.041 13.8 0.3 0.7 9.9 0.0 2.8 2 1 1 3 3 3 0 Proteins of 100 residues with WXG ApoLp-III PF07464.6 ETO09635.1 - 0.064 13.2 0.2 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF4014 PF13198.1 ETO09635.1 - 0.56 10.6 4.1 0.21 11.9 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) DUF2964 PF11177.3 ETO09635.1 - 10 6.1 7.5 2.2 8.2 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2964) DUF342 PF03961.8 ETO09637.1 - 0.00099 17.6 2.3 0.0014 17.1 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) Laminin_II PF06009.7 ETO09637.1 - 0.0034 17.1 0.8 0.006 16.3 0.5 1.4 1 0 0 1 1 1 1 Laminin Domain II DUF1640 PF07798.6 ETO09637.1 - 0.0041 17.1 1.2 0.0082 16.1 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) CASP_C PF08172.7 ETO09637.1 - 0.0091 15.0 0.7 0.012 14.6 0.5 1.3 1 0 0 1 1 1 1 CASP C terminal HALZ PF02183.13 ETO09637.1 - 0.018 14.7 0.9 1.7 8.3 0.0 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper Spc7 PF08317.6 ETO09637.1 - 0.02 13.5 4.4 0.031 12.9 3.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.3 ETO09637.1 - 0.025 14.3 5.6 0.081 12.6 2.0 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.10 ETO09637.1 - 3.6 7.1 10.9 5.4 6.5 1.8 2.9 2 1 1 3 3 3 0 Septum formation initiator Ribosomal_L23eN PF03939.8 ETO09637.1 - 3.8 7.6 5.3 0.44 10.6 0.4 1.8 2 0 0 2 2 2 0 Ribosomal protein L23, N-terminal domain WD40 PF00400.27 ETO09638.1 - 5.2e-05 22.9 1.4 0.99 9.3 0.0 3.9 3 2 0 3 3 3 2 WD domain, G-beta repeat FGGY_C PF02782.11 ETO09639.1 - 0.17 11.5 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain HSP70 PF00012.15 ETO09640.1 - 0.00062 17.8 0.1 0.00082 17.4 0.1 1.2 1 0 0 1 1 1 1 Hsp70 protein SrfB PF07520.6 ETO09640.1 - 0.016 12.7 0.0 0.018 12.5 0.0 1.1 1 0 0 1 1 1 0 Virulence factor SrfB EutA PF06277.6 ETO09640.1 - 0.12 10.9 0.1 0.29 9.7 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutA GST_N_2 PF13409.1 ETO09641.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain HSP70 PF00012.15 ETO09642.1 - 0.00025 19.1 0.0 0.00061 17.8 0.0 1.7 1 1 0 1 1 1 1 Hsp70 protein Cyclin_N PF00134.18 ETO09643.1 - 3.7e-06 26.5 0.4 5.9e-06 25.8 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain ADH_zinc_N PF00107.21 ETO09644.1 - 2.1e-21 75.8 0.0 4e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETO09644.1 - 1.5e-10 42.0 0.0 5.9e-10 40.1 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETO09644.1 - 0.02 14.6 0.0 0.056 13.2 0.0 1.8 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain FGGY_C PF02782.11 ETO09644.1 - 0.062 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain ETX_MTX2 PF03318.8 ETO09645.1 - 0.032 13.7 12.5 0.048 13.2 8.6 1.2 1 0 0 1 1 1 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 DUF2170 PF09938.4 ETO09646.1 - 0.026 13.8 0.5 0.041 13.2 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2170) EF-hand_1 PF00036.27 ETO09647.1 - 2e-25 86.0 9.3 4.2e-07 28.7 0.0 5.5 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 ETO09647.1 - 8.8e-20 70.6 18.7 1.7e-10 40.9 1.9 3.7 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO09647.1 - 2.4e-18 64.2 14.4 0.00017 21.2 0.1 6.0 6 0 0 6 6 6 4 EF-hand domain EF-hand_5 PF13202.1 ETO09647.1 - 1.6e-15 55.6 12.7 1.4e-05 24.2 0.0 5.0 5 0 0 5 5 5 3 EF hand Pkinase PF00069.20 ETO09647.1 - 7.9e-14 51.4 0.0 2e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain EF-hand_8 PF13833.1 ETO09647.1 - 7.6e-12 44.6 7.6 2.5e-05 23.8 0.2 3.4 2 2 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 ETO09647.1 - 4.8e-05 23.3 6.1 0.028 14.4 0.4 3.0 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 ETO09647.1 - 0.0026 17.4 3.6 0.61 9.8 0.1 2.8 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand RNA_pol_Rpb1_5 PF04998.12 ETO09647.1 - 0.025 13.8 1.3 0.038 13.2 0.9 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 His_Phos_1 PF00300.17 ETO09648.1 - 9.3e-05 22.5 0.0 9.3e-05 22.5 0.0 2.4 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 1) TEX19 PF15553.1 ETO09648.1 - 0.059 13.2 6.1 0.12 12.2 4.2 1.5 1 0 0 1 1 1 0 Testis-expressed protein 19 CENP-B_dimeris PF09026.5 ETO09648.1 - 0.17 12.1 7.0 0.44 10.8 4.9 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sporozoite_P67 PF05642.6 ETO09648.1 - 2 6.1 5.1 2.7 5.7 3.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen uDENN PF03456.13 ETO09649.1 - 3.4e-06 26.9 0.1 5.4e-05 23.0 0.1 2.3 1 1 0 1 1 1 1 uDENN domain FAM86 PF14904.1 ETO09649.1 - 0.077 12.7 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function DENN PF02141.16 ETO09650.1 - 2e-39 135.2 8.5 3.6e-39 134.3 5.9 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain RuvB_N PF05496.7 ETO09650.1 - 0.00091 18.3 0.7 0.0021 17.1 0.5 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus ENTH PF01417.15 ETO09650.1 - 0.0069 16.2 0.0 0.023 14.5 0.0 1.9 1 0 0 1 1 1 1 ENTH domain Nucleoplasmin PF03066.10 ETO09650.1 - 0.073 12.5 3.9 0.086 12.3 0.7 2.6 3 0 0 3 3 3 0 Nucleoplasmin dDENN PF03455.14 ETO09650.1 - 0.36 10.9 2.8 18 5.5 0.4 3.0 2 0 0 2 2 2 0 dDENN domain Mucin PF01456.12 ETO09650.1 - 2.5 7.8 42.8 1.6 8.5 26.4 2.7 2 0 0 2 2 2 0 Mucin-like glycoprotein Metallophos PF00149.23 ETO09651.1 - 3e-07 30.0 5.6 8e-06 25.3 3.9 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Herpes_UL6 PF01763.11 ETO09652.1 - 0.012 13.8 1.8 0.021 13.0 1.3 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like LIM PF00412.17 ETO09652.1 - 0.017 15.1 4.6 0.017 15.1 3.2 4.1 4 0 0 4 4 4 0 LIM domain bZIP_1 PF00170.16 ETO09652.1 - 0.049 13.5 8.3 2 8.4 0.0 3.5 3 0 0 3 3 3 0 bZIP transcription factor Mnd1 PF03962.10 ETO09652.1 - 0.07 12.7 6.7 0.16 11.5 3.2 2.2 2 0 0 2 2 2 0 Mnd1 family DUF4530 PF15039.1 ETO09652.1 - 0.15 12.0 1.5 3.5 7.5 1.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4530) IFP_35_N PF07334.8 ETO09652.1 - 0.25 11.3 0.2 0.25 11.3 0.1 2.7 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DivIVA PF05103.8 ETO09652.1 - 0.27 11.2 10.3 0.058 13.4 3.5 2.4 2 0 0 2 2 2 0 DivIVA protein DivIC PF04977.10 ETO09652.1 - 0.52 9.8 11.0 9.7 5.7 0.1 3.5 3 0 0 3 3 3 0 Septum formation initiator KLRAQ PF10205.4 ETO09652.1 - 0.53 10.3 12.7 0.86 9.6 1.7 2.8 2 1 1 3 3 3 0 Predicted coiled-coil domain-containing protein DUF1364 PF07102.7 ETO09652.1 - 0.8 9.6 6.4 5 7.0 0.0 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1364) IncA PF04156.9 ETO09652.1 - 1.1 8.8 8.5 1 8.8 3.8 2.2 2 0 0 2 2 2 0 IncA protein Cep57_CLD_2 PF14197.1 ETO09652.1 - 1.1 9.1 9.9 2.7 8.0 0.7 3.0 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 DUF342 PF03961.8 ETO09652.1 - 1.2 7.4 8.0 0.17 10.2 2.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF342) bZIP_2 PF07716.10 ETO09652.1 - 1.7 8.4 15.8 9.4 6.1 2.6 3.4 3 0 0 3 3 3 0 Basic region leucine zipper DUF4407 PF14362.1 ETO09652.1 - 2.6 6.9 7.3 0.28 10.0 2.2 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF904 PF06005.7 ETO09652.1 - 4.8 7.5 17.0 1.1 9.6 2.4 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF904) SWIRM PF04433.12 ETO09654.1 - 2e-20 72.7 0.4 3.1e-19 68.8 0.3 2.8 1 1 0 1 1 1 1 SWIRM domain DUF3232 PF11554.3 ETO09654.1 - 0.00024 21.0 0.1 0.00058 19.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3232) Tox-MPTase2 PF15638.1 ETO09655.1 - 0.069 12.6 0.7 0.31 10.5 0.2 2.1 1 1 0 1 1 1 0 Metallopeptidase toxin 2 ubiquitin PF00240.18 ETO09656.1 - 1.7e-06 27.3 0.0 3.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 ETO09656.1 - 0.00043 19.9 0.0 0.0012 18.5 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ECSIT PF06239.6 ETO09658.1 - 0.0054 15.6 0.6 0.0083 15.0 0.4 1.3 1 0 0 1 1 1 1 Evolutionarily conserved signalling intermediate in Toll pathway DUF2726 PF10881.3 ETO09658.1 - 0.089 12.4 0.1 3.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2726) Argos PF11581.3 ETO09658.1 - 0.093 12.6 0.8 3.1 7.7 0.2 2.1 2 0 0 2 2 2 0 Antagonist of EGFR signalling, Argos POPLD PF08170.7 ETO09658.1 - 0.24 11.2 1.5 0.24 11.2 0.2 1.7 2 0 0 2 2 2 0 POPLD (NUC188) domain SAM_1 PF00536.25 ETO09659.1 - 0.0019 18.3 0.2 0.17 12.0 0.1 2.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO09659.1 - 0.0041 16.9 2.1 2.4 8.0 0.2 3.5 3 1 0 3 3 3 2 SAM domain (Sterile alpha motif) Menin PF05053.8 ETO09659.1 - 0.0083 14.3 2.0 0.011 13.9 1.4 1.2 1 0 0 1 1 1 1 Menin zf-C2H2_2 PF12756.2 ETO09660.1 - 1.4e-21 76.4 0.5 1.4e-21 76.4 0.4 2.5 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Myc_N PF01056.13 ETO09660.1 - 0.22 10.6 4.1 0.48 9.5 2.8 1.5 1 0 0 1 1 1 0 Myc amino-terminal region zf-C2H2 PF00096.21 ETO09660.1 - 8.1 7.0 10.5 6.7 7.2 1.5 3.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF3439 PF11921.3 ETO09661.1 - 0.062 13.0 0.6 0.067 12.9 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 ETO09661.1 - 0.2 9.4 2.5 0.19 9.4 1.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SPRY PF00622.23 ETO09662.1 - 4.3e-05 23.6 0.2 0.00015 21.8 0.0 1.8 2 0 0 2 2 2 1 SPRY domain DEAD PF00270.24 ETO09664.1 - 1.5e-18 66.8 0.0 3.8e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETO09664.1 - 2.9e-12 46.2 0.0 1.1e-11 44.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.1 ETO09664.1 - 0.015 15.4 0.0 0.055 13.6 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix domain DUF3439 PF11921.3 ETO09664.1 - 0.022 14.4 5.9 0.068 12.9 4.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Myc_N PF01056.13 ETO09664.1 - 0.077 12.1 7.2 0.74 8.9 0.2 2.3 2 0 0 2 2 2 0 Myc amino-terminal region SSP160 PF06933.6 ETO09664.1 - 3.5 5.4 9.0 7.9 4.3 6.2 1.5 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dynamin_N PF00350.18 ETO09664.1 - 4.4 7.0 8.3 11 5.8 0.4 3.1 2 1 1 3 3 3 0 Dynamin family PRD_Mga PF08270.6 ETO09665.1 - 0.0097 15.2 0.8 0.017 14.4 0.6 1.4 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) PRD domain PLA2G12 PF06951.6 ETO09666.1 - 2.9e-13 49.8 17.7 1.6e-12 47.4 12.3 1.9 1 1 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) DnaJ PF00226.26 ETO09667.1 - 5.6e-14 51.6 0.2 1.5e-13 50.2 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain PRAI PF00697.17 ETO09667.1 - 0.018 14.6 0.2 0.028 13.9 0.1 1.3 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase CDC45 PF02724.9 ETO09667.1 - 0.045 11.7 9.9 0.052 11.5 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Acetyltransf_2 PF00797.12 ETO09667.1 - 0.13 11.8 0.7 0.15 11.6 0.5 1.2 1 0 0 1 1 1 0 N-acetyltransferase Membralin PF09746.4 ETO09667.1 - 0.3 10.1 3.9 0.36 9.8 2.7 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF2052 PF09747.4 ETO09667.1 - 0.44 10.4 10.8 0.53 10.1 7.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF2146 PF10220.4 ETO09667.1 - 0.69 7.8 9.7 0.86 7.5 6.7 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) CDC37_C PF08564.5 ETO09667.1 - 0.85 9.4 7.7 0.29 10.9 3.2 1.8 2 1 0 2 2 2 0 Cdc37 C terminal domain DDHD PF02862.12 ETO09667.1 - 6.7 6.4 9.0 8.7 6.0 6.2 1.2 1 0 0 1 1 1 0 DDHD domain OAD_gamma PF04277.8 ETO09667.1 - 7.2 7.0 8.0 1e+02 3.3 5.5 2.4 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Rota_VP2 PF05087.7 ETO09667.1 - 8.2 4.1 8.7 9.5 3.9 6.0 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein DUF4613 PF15390.1 ETO09667.1 - 8.4 4.4 8.1 8.3 4.4 5.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) LIM PF00412.17 ETO09668.1 - 4.6e-07 29.7 6.5 9e-07 28.8 4.5 1.5 1 0 0 1 1 1 1 LIM domain Ribosomal_L27 PF01016.14 ETO09670.1 - 1.5e-09 37.4 0.5 2.9e-09 36.6 0.3 1.5 1 0 0 1 1 1 1 Ribosomal L27 protein DUF3912 PF13051.1 ETO09670.1 - 0.017 14.8 1.0 0.33 10.7 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3912) CHASE3 PF05227.8 ETO09670.1 - 0.13 11.9 0.3 0.13 11.9 0.2 1.9 1 1 0 2 2 2 0 CHASE3 domain 2OG-FeII_Oxy_3 PF13640.1 ETO09671.1 - 1e-11 45.2 0.0 2.9e-11 43.7 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 ETO09671.1 - 0.00027 21.1 0.1 0.0013 18.9 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 ETO09671.1 - 0.00036 20.1 0.0 0.00092 18.8 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_2 PF13532.1 ETO09671.1 - 0.0025 17.6 0.0 0.0056 16.5 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily REJ PF02010.10 ETO09673.1 - 1.3e-10 40.1 0.7 2.6e-10 39.2 0.5 1.5 1 0 0 1 1 1 1 REJ domain GPS PF01825.16 ETO09673.1 - 6.9e-06 26.0 4.1 6.9e-06 26.0 2.8 2.6 3 1 0 3 3 3 1 Latrophilin/CL-1-like GPS domain Cytomega_TRL10 PF06084.6 ETO09673.1 - 0.12 12.2 2.2 0.12 12.2 0.0 2.1 3 0 0 3 3 3 0 Cytomegalovirus TRL10 protein Myotub-related PF06602.9 ETO09674.1 - 6.1e-68 229.1 4.0 3.9e-58 196.9 0.6 2.3 1 1 1 2 2 2 2 Myotubularin-like phosphatase domain FYVE PF01363.16 ETO09674.1 - 1.4e-09 37.6 10.9 3.8e-09 36.3 7.5 1.7 1 0 0 1 1 1 1 FYVE zinc finger Y_phosphatase3 PF13350.1 ETO09674.1 - 0.0027 17.9 0.0 0.0097 16.1 0.0 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 ETO09674.1 - 0.0079 15.5 0.1 0.018 14.3 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CSD PF00313.17 ETO09675.1 - 0.003 17.2 0.4 0.59 9.9 0.0 3.3 4 0 0 4 4 4 2 'Cold-shock' DNA-binding domain DUF3439 PF11921.3 ETO09675.1 - 0.0036 17.0 3.6 0.016 14.9 2.5 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) ArfGap PF01412.13 ETO09676.1 - 0.025 14.3 0.2 0.059 13.1 0.1 1.6 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf ShK PF01549.19 ETO09677.1 - 4.9e-05 23.5 4.6 4.9e-05 23.5 3.2 2.2 2 0 0 2 2 2 1 ShK domain-like PAN_4 PF14295.1 ETO09677.1 - 0.016 14.9 2.3 0.017 14.8 0.0 2.2 2 0 0 2 2 2 0 PAN domain SNF2_N PF00176.18 ETO09679.1 - 1.8e-22 79.5 0.0 1e-21 77.0 0.0 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 ETO09679.1 - 0.022 14.5 1.5 0.2 11.4 0.0 2.8 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Exostosin PF03016.10 ETO09680.1 - 0.06 12.3 0.2 0.14 11.1 0.1 1.6 1 1 1 2 2 2 0 Exostosin family YcxB PF14317.1 ETO09680.1 - 0.068 12.4 0.1 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 YcxB-like protein PDZ PF00595.19 ETO09681.1 - 0.066 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) Nucleoplasmin PF03066.10 ETO09681.1 - 0.39 10.2 3.4 0.71 9.3 0.0 2.1 1 1 1 2 2 2 0 Nucleoplasmin DUF3245 PF11595.3 ETO09681.1 - 1.1 9.4 0.1 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) SP_C-Propep PF08999.5 ETO09682.1 - 0.014 14.8 0.2 0.021 14.3 0.1 1.3 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide OST3_OST6 PF04756.8 ETO09682.1 - 0.042 13.4 1.9 0.061 12.8 0.5 1.7 1 1 1 2 2 2 0 OST3 / OST6 family Octopine_DH PF02317.12 ETO09682.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.3 1 1 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Brix PF04427.13 ETO09683.1 - 7.9e-05 22.4 0.7 0.00015 21.4 0.5 1.5 1 0 0 1 1 1 1 Brix domain DUF188 PF02639.9 ETO09683.1 - 0.0077 15.6 1.2 0.94 8.9 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized BCR, YaiI/YqxD family COG1671 alpha-hel2 PF14456.1 ETO09683.1 - 0.79 8.4 3.8 1.1 7.9 2.6 1.1 1 0 0 1 1 1 0 Alpha-helical domain 2 Borrelia_P83 PF05262.6 ETO09683.1 - 1.3 7.2 9.0 1.5 6.9 6.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein IBB PF01749.15 ETO09684.1 - 0.00018 21.5 7.3 0.00018 21.5 5.0 1.9 2 0 0 2 2 2 1 Importin beta binding domain 2OG-FeII_Oxy_3 PF13640.1 ETO09684.1 - 0.00026 21.4 0.1 0.00055 20.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 ETO09684.1 - 0.012 15.2 0.1 0.024 14.2 0.1 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF2053 PF09767.4 ETO09685.1 - 0.019 14.9 0.2 0.031 14.2 0.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2053) RNA_pol_Rpb1_3 PF04983.13 ETO09685.1 - 0.074 12.7 0.1 0.13 11.9 0.1 1.4 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 3 Aldose_epim PF01263.15 ETO09689.1 - 6e-29 101.1 0.4 9e-29 100.5 0.3 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Mak10 PF04112.8 ETO09690.1 - 0.028 13.6 1.9 0.084 12.0 0.5 2.3 2 1 0 2 2 2 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase SDA1 PF05285.7 ETO09691.1 - 4.8 6.3 20.7 5.1 6.2 14.3 1.1 1 0 0 1 1 1 0 SDA1 TPR_11 PF13414.1 ETO09693.1 - 4.1e-15 55.1 2.3 1.4e-11 43.9 0.1 2.4 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 ETO09693.1 - 1.6e-09 36.9 0.6 0.012 15.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO09693.1 - 1.7e-09 36.8 2.8 0.0012 18.3 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO09693.1 - 2.4e-06 26.8 4.1 0.00082 18.9 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO09693.1 - 7.2e-06 25.8 2.8 0.00034 20.4 0.2 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat NARP1 PF12569.3 ETO09693.1 - 0.00026 19.8 0.4 0.00039 19.2 0.3 1.3 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 Apc3 PF12895.2 ETO09693.1 - 0.0011 19.0 5.1 0.012 15.7 3.1 2.4 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 ETO09693.1 - 0.0014 18.2 0.1 0.51 10.2 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO09693.1 - 0.0024 18.4 0.0 4.1 8.1 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO09693.1 - 0.0087 16.1 0.7 0.14 12.4 0.0 3.2 3 1 0 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO09693.1 - 0.014 15.7 0.7 4.5 7.9 0.3 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO09693.1 - 0.064 13.1 0.4 0.064 13.1 0.3 2.1 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat SPX PF03105.14 ETO09694.1 - 0.0078 16.0 6.6 0.0089 15.8 4.6 1.1 1 0 0 1 1 1 1 SPX domain BUD22 PF09073.5 ETO09694.1 - 1.2 8.1 10.3 1.1 8.1 7.1 1.2 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 ETO09694.1 - 1.6 7.1 17.9 1.7 7.0 12.4 1.1 1 0 0 1 1 1 0 Daxx Family BAF1_ABF1 PF04684.8 ETO09695.1 - 0.003 16.5 6.8 0.0041 16.0 4.7 1.2 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor DUF4451 PF14616.1 ETO09695.1 - 0.0089 15.7 0.4 0.012 15.3 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) FliD_N PF02465.13 ETO09695.1 - 0.069 13.5 1.0 0.12 12.7 0.7 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus TSA PF03249.8 ETO09695.1 - 5.4 5.4 6.4 7.1 5.0 4.4 1.1 1 0 0 1 1 1 0 Type specific antigen zf-Di19 PF05605.7 ETO09696.1 - 7.8e-06 25.9 7.5 4.6e-05 23.4 4.9 2.6 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding ZZ PF00569.12 ETO09696.1 - 0.0066 15.9 3.4 0.02 14.4 0.6 2.7 2 0 0 2 2 2 1 Zinc finger, ZZ type U-box PF04564.10 ETO09697.1 - 6.5e-23 80.4 0.8 1.7e-22 79.1 0.5 1.8 1 0 0 1 1 1 1 U-box domain Mto2_bdg PF12808.2 ETO09697.1 - 8.2 6.6 9.4 4.7 7.4 0.5 3.2 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Pkinase PF00069.20 ETO09700.1 - 1.3e-28 99.9 0.0 9.4e-21 74.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO09700.1 - 2.1e-12 46.7 0.0 1.3e-06 27.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase SIC PF03482.8 ETO09700.1 - 0.0086 15.7 0.0 0.009 15.6 0.0 1.2 1 0 0 1 1 1 1 sic protein DUF4239 PF14023.1 ETO09701.1 - 0.043 13.1 2.7 0.13 11.6 1.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) PEHE PF15275.1 ETO09701.1 - 0.049 14.0 2.2 0.12 12.8 1.5 1.6 1 0 0 1 1 1 0 PEHE domain STAS_2 PF13466.1 ETO09701.1 - 0.059 13.3 0.4 0.12 12.4 0.3 1.4 1 0 0 1 1 1 0 STAS domain PIRT PF15099.1 ETO09701.1 - 0.11 11.7 0.1 0.11 11.7 0.1 2.1 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family DUF3987 PF13148.1 ETO09701.1 - 0.79 8.2 5.2 1.3 7.5 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Peptidase_S49_N PF08496.5 ETO09701.1 - 0.8 9.4 4.9 5.7 6.7 3.5 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF3464 PF11947.3 ETO09701.1 - 1.1 8.6 3.6 4.4 6.7 2.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) SR-25 PF10500.4 ETO09701.1 - 2.3 7.6 14.0 0.015 14.7 3.3 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein NS3_envE PF02723.9 ETO09702.1 - 2.4 8.1 6.0 22 5.0 0.7 2.8 2 0 0 2 2 2 0 Non-structural protein NS3/Small envelope protein E DUF3490 PF11995.3 ETO09704.1 - 0.00089 18.8 5.2 0.00096 18.7 0.5 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3490) IQ PF00612.22 ETO09704.1 - 0.012 15.2 3.3 1.9 8.3 0.0 4.2 4 0 0 4 4 4 0 IQ calmodulin-binding motif LMF1 PF06762.9 ETO09705.1 - 3.7e-34 118.1 27.1 1e-30 106.8 14.5 4.7 1 1 0 2 2 2 2 Lipase maturation factor EphA2_TM PF14575.1 ETO09705.1 - 0.024 15.0 0.6 4.2 7.8 0.0 3.8 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain LMF1 PF06762.9 ETO09706.1 - 2.1e-05 23.5 0.2 3.6e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Lipase maturation factor EII-GUT PF03608.8 ETO09706.1 - 0.027 14.3 1.2 0.34 10.7 0.0 2.2 1 1 1 2 2 2 0 PTS system enzyme II sorbitol-specific factor Linker_histone PF00538.14 ETO09708.1 - 0.00015 21.7 0.1 0.00015 21.7 0.1 1.8 2 0 0 2 2 2 1 linker histone H1 and H5 family ATE_C PF04377.10 ETO09708.1 - 0.016 15.2 0.4 0.031 14.3 0.0 1.6 2 0 0 2 2 2 0 Arginine-tRNA-protein transferase, C terminus Put_Phosphatase PF06888.7 ETO09709.1 - 0.00033 19.9 0.0 0.00041 19.6 0.0 1.1 1 0 0 1 1 1 1 Putative Phosphatase Put_Phosphatase PF06888.7 ETO09710.1 - 7.9e-25 87.3 1.9 4e-22 78.5 1.3 2.8 1 1 0 1 1 1 1 Putative Phosphatase HAD PF12710.2 ETO09710.1 - 0.0055 16.8 0.0 0.0086 16.2 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cytochrom_c3_2 PF14537.1 ETO09710.1 - 0.24 11.7 2.8 0.18 12.1 0.8 1.7 2 0 0 2 2 2 0 Cytochrome c3 DUF1325 PF07039.6 ETO09711.1 - 3.7e-17 62.1 0.1 7.4e-17 61.1 0.1 1.5 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF4537 PF15057.1 ETO09711.1 - 4.4e-05 23.2 0.2 0.017 14.9 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4537) DUF4361 PF14274.1 ETO09711.1 - 0.0076 15.9 4.7 0.076 12.6 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4361) SRP19 PF01922.12 ETO09712.1 - 0.1 13.1 1.6 0.19 12.3 1.1 1.4 1 0 0 1 1 1 0 SRP19 protein YqzE PF14038.1 ETO09712.1 - 0.54 10.0 3.5 1.2 8.9 2.4 1.7 1 1 0 1 1 1 0 YqzE-like protein ETRAMP PF09716.5 ETO09712.1 - 0.64 10.0 4.4 1.4 8.9 3.0 1.9 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Aa_trans PF01490.13 ETO09713.1 - 2.1e-57 194.4 24.6 3.2e-57 193.8 17.0 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2451 PF10474.4 ETO09714.1 - 2.7e-10 40.4 1.0 5.7e-10 39.3 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) DUF2450 PF10475.4 ETO09714.1 - 3e-10 39.4 6.9 8.2e-10 38.0 4.8 1.7 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) WH1 PF00568.18 ETO09715.1 - 0.0022 17.6 0.1 0.0047 16.6 0.0 1.6 1 0 0 1 1 1 1 WH1 domain HABP4_PAI-RBP1 PF04774.10 ETO09716.1 - 4.8e-14 52.7 7.3 4.8e-14 52.7 5.0 3.1 2 2 0 2 2 2 1 Hyaluronan / mRNA binding family DUF2762 PF10960.3 ETO09716.1 - 0.21 11.3 4.9 0.82 9.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2762) Daxx PF03344.10 ETO09717.1 - 0.011 14.2 25.7 0.022 13.2 17.8 1.4 1 0 0 1 1 1 0 Daxx Family MMPL PF03176.10 ETO09718.1 - 4.3e-14 51.9 0.0 2e-13 49.8 0.0 1.7 1 1 0 1 1 1 1 MMPL family SAC3_GANP PF03399.11 ETO09719.1 - 2.2e-31 109.0 0.1 4e-31 108.1 0.1 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Phtf-FEM1B_bdg PF12129.3 ETO09719.1 - 0.18 11.1 0.9 0.64 9.3 0.2 2.1 2 0 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor Draxin PF15550.1 ETO09719.1 - 0.45 10.1 11.9 0.66 9.5 8.2 1.2 1 0 0 1 1 1 0 Draxin Piwi PF02171.12 ETO09720.1 - 2.3e-13 49.8 0.0 9.4e-13 47.7 0.0 1.9 1 1 0 1 1 1 1 Piwi domain Med2 PF11214.3 ETO09720.1 - 2.3 8.2 6.7 1.3 9.1 1.4 2.8 3 0 0 3 3 3 0 Mediator complex subunit 2 PEMT PF04191.8 ETO09721.1 - 4.1e-13 49.3 0.1 5.8e-13 48.8 0.1 1.2 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.9 ETO09721.1 - 8.4e-13 48.3 0.4 1.1e-12 47.9 0.3 1.2 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.12 ETO09721.1 - 0.034 12.7 0.3 0.039 12.5 0.2 1.1 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 ETO09721.1 - 0.04 13.2 0.1 0.055 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) F-box-like PF12937.2 ETO09723.1 - 0.079 12.6 5.6 0.099 12.3 1.0 2.6 2 0 0 2 2 2 0 F-box-like Amino_oxidase PF01593.19 ETO09724.1 - 5e-27 95.0 0.0 3.4e-14 52.7 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 ETO09724.1 - 8e-14 51.4 0.1 2.5e-12 46.6 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETO09724.1 - 5.3e-07 28.8 0.1 1.2e-06 27.6 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 ETO09724.1 - 7.4e-05 22.0 0.0 0.00012 21.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 ETO09724.1 - 0.00013 21.9 0.6 0.025 14.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETO09724.1 - 0.00013 22.1 0.2 0.0018 18.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETO09724.1 - 0.00016 20.3 0.8 0.00048 18.7 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 ETO09724.1 - 0.00044 19.4 0.1 0.00082 18.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 ETO09724.1 - 0.00056 19.0 2.6 0.0014 17.7 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 ETO09724.1 - 0.005 16.6 0.0 0.014 15.1 0.0 1.9 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 ETO09724.1 - 0.0083 16.5 2.2 0.017 15.5 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETO09724.1 - 0.012 14.5 0.3 0.017 13.9 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 ETO09724.1 - 0.023 13.3 0.1 0.035 12.7 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Shikimate_DH PF01488.15 ETO09724.1 - 0.11 12.5 0.2 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 ETO09724.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Atrophin-1 PF03154.10 ETO09724.1 - 1.3 7.1 5.6 1.9 6.5 3.9 1.1 1 0 0 1 1 1 0 Atrophin-1 family ABC_tran PF00005.22 ETO09726.1 - 3.5e-14 53.2 0.0 3.5e-14 53.2 0.0 3.0 2 2 0 2 2 1 1 ABC transporter ABC_membrane PF00664.18 ETO09726.1 - 2e-08 33.9 0.3 2e-08 33.9 0.2 3.1 2 1 1 3 3 3 1 ABC transporter transmembrane region Mucin PF01456.12 ETO09726.1 - 8.3e-05 22.3 4.8 8.3e-05 22.3 3.4 2.3 2 0 0 2 2 2 1 Mucin-like glycoprotein Arch_ATPase PF01637.13 ETO09726.1 - 0.0031 17.2 0.9 0.057 13.1 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase Dynamin_N PF00350.18 ETO09726.1 - 0.011 15.6 0.1 0.011 15.6 0.1 3.1 3 1 1 4 4 3 0 Dynamin family AAA_29 PF13555.1 ETO09726.1 - 0.015 14.8 0.4 0.037 13.5 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 ETO09726.1 - 0.021 15.3 0.1 0.021 15.3 0.1 2.9 2 1 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 ETO09726.1 - 0.091 12.7 0.1 0.091 12.7 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase NESP55 PF06390.7 ETO09726.1 - 0.14 11.5 5.8 0.27 10.5 4.0 1.4 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) AAA_23 PF13476.1 ETO09726.1 - 0.32 11.3 0.1 0.32 11.3 0.1 3.5 3 1 0 3 3 2 0 AAA domain SMC_N PF02463.14 ETO09726.1 - 0.43 9.7 10.5 0.17 11.0 0.1 3.1 2 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain Atrophin-1 PF03154.10 ETO09726.1 - 0.83 7.7 14.7 0.33 9.0 1.8 2.3 2 0 0 2 2 2 0 Atrophin-1 family DUF2246 PF10229.4 ETO09728.1 - 1.3e-15 57.4 0.7 5.3e-09 35.7 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2246) MRAP PF15183.1 ETO09728.1 - 0.00043 19.8 4.7 0.0016 17.9 0.0 2.5 2 0 0 2 2 2 1 Melanocortin-2 receptor accessory protein family DUF2029 PF09594.5 ETO09728.1 - 0.12 11.8 1.7 0.18 11.2 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) DUF4131 PF13567.1 ETO09728.1 - 1.5 8.2 4.5 2.4 7.5 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) ETRAMP PF09716.5 ETO09729.1 - 0.11 12.4 2.2 0.35 10.8 0.6 2.5 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) WD40 PF00400.27 ETO09730.1 - 4.3e-54 178.5 23.1 1.2e-11 44.0 0.0 7.1 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO09730.1 - 5e-14 51.3 7.3 0.0013 16.9 0.0 5.9 1 1 4 6 6 6 6 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO09730.1 - 0.052 13.0 0.1 9.9 5.5 0.0 2.9 1 1 1 3 3 3 0 PQQ-like domain AA_permease PF00324.16 ETO09731.1 - 7.9e-19 67.3 2.4 1.1e-18 66.8 1.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4401 PF14351.1 ETO09731.1 - 0.052 12.5 5.0 0.066 12.1 2.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4401) GCV_T PF01571.16 ETO09731.1 - 0.13 11.6 0.1 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain FaeA PF04703.7 ETO09731.1 - 0.15 12.1 0.1 19 5.4 0.0 2.9 2 0 0 2 2 2 0 FaeA-like protein Zip PF02535.17 ETO09731.1 - 0.42 9.5 6.5 1.1 8.2 4.5 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4205 PF13898.1 ETO09732.1 - 6.5e-14 51.4 0.1 8e-09 34.6 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4205) Ras PF00071.17 ETO09733.1 - 1.3e-22 79.9 0.2 1.8e-22 79.4 0.1 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO09733.1 - 0.00012 22.4 0.2 0.00058 20.3 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Troponin PF00992.15 ETO09734.1 - 0.02 14.9 8.2 0.037 14.1 5.7 1.5 1 1 0 1 1 1 0 Troponin DUF3438 PF11920.3 ETO09734.1 - 0.035 12.9 6.3 0.044 12.6 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) Glyco_hydro_65m PF03632.10 ETO09734.1 - 0.076 11.6 3.1 0.089 11.4 2.1 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 65 central catalytic domain YPEB PF14620.1 ETO09734.1 - 0.42 9.5 10.3 0.55 9.1 7.2 1.2 1 0 0 1 1 1 0 YpeB sporulation GAGA_bind PF06217.7 ETO09734.1 - 0.73 9.7 10.2 0.85 9.5 7.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Radical_SAM_N PF08497.5 ETO09734.1 - 2.3 7.0 4.9 3 6.6 3.4 1.2 1 0 0 1 1 1 0 Radical SAM N-terminal Ly49 PF08391.5 ETO09734.1 - 7.5 6.7 21.1 0.65 10.1 7.0 2.1 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region DUF89 PF01937.14 ETO09736.1 - 1.2e-39 136.1 0.2 1.4e-39 135.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF2578 PF10843.3 ETO09736.1 - 0.099 12.3 0.5 0.14 11.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2578) DUF89 PF01937.14 ETO09737.1 - 7.7e-08 31.5 0.8 1e-07 31.0 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF89 AgrB PF04647.10 ETO09737.1 - 0.013 14.5 0.1 0.021 13.9 0.1 1.2 1 0 0 1 1 1 0 Accessory gene regulator B DUF2521 PF10730.4 ETO09737.1 - 0.06 13.1 2.2 0.1 12.3 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2521) DUF3007 PF11460.3 ETO09737.1 - 0.22 11.6 1.4 0.24 11.4 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3007) Tnp_P_element PF12017.3 ETO09739.1 - 0.0055 15.9 1.7 0.01 15.1 1.2 1.3 1 0 0 1 1 1 1 Transposase protein S1FA PF04689.8 ETO09739.1 - 0.071 12.9 0.6 0.16 11.8 0.4 1.6 1 0 0 1 1 1 0 DNA binding protein S1FA Daxx PF03344.10 ETO09739.1 - 1.9 6.9 51.5 0.014 13.8 9.2 2.2 2 0 0 2 2 2 0 Daxx Family SDA1 PF05285.7 ETO09739.1 - 6.1 6.0 43.7 0.4 9.9 8.9 2.5 2 1 0 2 2 2 0 SDA1 ETRAMP PF09716.5 ETO09740.1 - 0.017 15.0 0.0 0.046 13.6 0.0 1.8 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Pex24p PF06398.6 ETO09740.1 - 0.11 11.3 4.1 0.086 11.6 1.9 1.3 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin POX PF07526.6 ETO09742.1 - 0.018 15.2 4.4 0.018 15.2 3.0 2.6 3 0 0 3 3 3 0 Associated with HOX zf-Paramyx-P PF13008.2 ETO09742.1 - 0.079 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding domain of Paramyxoviridae V protein Lipase_3 PF01764.20 ETO09743.1 - 7.6e-14 51.5 0.0 2.7e-13 49.7 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 ETO09743.1 - 0.0026 17.1 0.0 0.0047 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 ETO09743.1 - 0.0085 15.8 0.0 0.022 14.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF506 PF04720.7 ETO09743.1 - 0.062 12.9 6.4 0.13 11.8 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF506) WD40 PF00400.27 ETO09744.1 - 9e-60 196.5 17.9 1.2e-12 47.1 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO09744.1 - 2.5e-08 32.5 13.6 0.084 10.9 0.1 5.0 1 1 4 5 5 5 5 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO09744.1 - 2e-05 23.0 0.9 0.13 10.4 0.0 3.4 2 2 2 4 4 4 3 Cytochrome D1 heme domain SGL PF08450.7 ETO09744.1 - 0.00029 20.2 0.2 0.67 9.2 0.0 2.8 2 1 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Hira PF07569.6 ETO09744.1 - 0.0014 17.8 3.3 2.2 7.4 0.0 4.1 2 1 3 5 5 5 2 TUP1-like enhancer of split Str_synth PF03088.11 ETO09744.1 - 0.0019 18.1 0.2 6.5 6.8 0.0 4.4 3 2 1 4 4 4 1 Strictosidine synthase DUF3601 PF12208.3 ETO09744.1 - 0.0054 16.6 0.0 8.3 6.4 0.0 4.3 3 2 3 6 6 6 1 Domain of unknown function (DUF3601) Ricin_B_lectin PF00652.17 ETO09744.1 - 0.022 14.7 7.7 0.26 11.3 0.8 3.2 2 1 1 3 3 3 0 Ricin-type beta-trefoil lectin domain DUF1652 PF07865.6 ETO09744.1 - 0.061 12.9 0.2 14 5.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1652) EnY2 PF10163.4 ETO09744.1 - 0.087 12.7 0.1 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Transcription factor e(y)2 zf-C3HC4_3 PF13920.1 ETO09745.1 - 2e-09 36.9 9.0 3.5e-09 36.2 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO09745.1 - 1e-08 35.0 10.1 2.2e-08 33.9 7.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO09745.1 - 2.1e-08 33.7 9.7 5.6e-08 32.3 6.7 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 ETO09745.1 - 5.3e-07 29.1 10.7 1.5e-06 27.7 7.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO09745.1 - 8e-07 28.7 8.8 2e-06 27.5 6.1 1.7 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.1 ETO09745.1 - 9.7e-05 21.8 2.8 0.00023 20.6 1.9 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 ETO09745.1 - 0.00043 20.0 2.7 0.00094 18.9 1.8 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 ETO09745.1 - 0.0013 18.4 9.1 0.0013 18.4 6.3 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 ETO09745.1 - 0.0079 16.2 4.2 0.024 14.7 2.9 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_4 PF14570.1 ETO09745.1 - 0.088 12.4 9.4 0.039 13.5 4.5 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 ETO09745.1 - 0.15 11.9 2.6 0.35 10.7 1.8 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 ETO09745.1 - 0.31 10.5 5.0 0.77 9.3 3.5 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 ETO09745.1 - 0.85 9.5 10.9 0.57 10.1 5.3 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-MIZ PF02891.15 ETO09745.1 - 1.6 8.3 8.2 3.8 7.0 5.7 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DZR PF12773.2 ETO09745.1 - 7.4 6.4 8.1 27 4.6 5.6 1.9 1 1 0 1 1 1 0 Double zinc ribbon RasGEF PF00617.14 ETO09746.1 - 7.6e-11 42.0 0.0 7.2e-10 38.8 0.0 2.0 2 0 0 2 2 2 1 RasGEF domain MSC PF09402.5 ETO09746.1 - 0.061 12.0 0.2 0.088 11.5 0.1 1.3 1 1 0 1 1 1 0 Man1-Src1p-C-terminal domain UPF0104 PF03706.8 ETO09746.1 - 0.13 11.4 0.6 0.16 11.1 0.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) WBP-1 PF11669.3 ETO09746.1 - 0.14 12.2 0.3 0.26 11.4 0.2 1.4 1 0 0 1 1 1 0 WW domain-binding protein 1 BatA PF07584.6 ETO09746.1 - 0.15 12.3 0.3 0.24 11.6 0.2 1.3 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Sec66 PF09802.4 ETO09746.1 - 0.18 11.1 3.1 0.78 9.0 2.2 2.0 1 1 0 1 1 1 0 Preprotein translocase subunit Sec66 DUF1434 PF07254.7 ETO09746.1 - 0.18 11.5 1.2 0.46 10.3 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1434) RasGEF PF00617.14 ETO09747.1 - 1.1e-20 74.1 2.0 1.2e-20 74.0 0.1 2.0 2 0 0 2 2 2 1 RasGEF domain PUB PF09409.5 ETO09747.1 - 1.6e-07 30.9 0.0 6.2e-07 29.0 0.0 2.0 1 0 0 1 1 1 1 PUB domain Ndc1_Nup PF09531.5 ETO09747.1 - 0.009 14.4 13.7 0.093 11.1 4.3 2.1 2 0 0 2 2 2 2 Nucleoporin protein Ndc1-Nup RasGEF_N PF00618.15 ETO09747.1 - 0.01 15.9 1.1 0.01 15.9 0.8 3.0 3 1 0 3 3 3 0 RasGEF N-terminal motif DUF658 PF04936.7 ETO09747.1 - 0.039 13.8 2.9 0.24 11.2 2.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF658) DUF3365 PF11845.3 ETO09747.1 - 0.58 9.9 5.1 0.39 10.5 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3365) Nucleotid_trans PF03407.11 ETO09748.1 - 3.4e-14 53.1 0.2 3.4e-14 53.1 0.1 1.6 2 0 0 2 2 1 1 Nucleotide-diphospho-sugar transferase CDC45 PF02724.9 ETO09748.1 - 0.0071 14.4 6.6 0.009 14.0 4.6 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF775 PF05603.7 ETO09748.1 - 0.016 14.6 3.8 0.029 13.8 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF775) YqfQ PF14181.1 ETO09748.1 - 0.18 11.8 8.8 0.32 11.0 6.1 1.4 1 0 0 1 1 1 0 YqfQ-like protein BAF1_ABF1 PF04684.8 ETO09748.1 - 0.24 10.2 18.0 0.34 9.7 12.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Hid1 PF12722.2 ETO09748.1 - 0.67 7.5 6.2 0.86 7.2 4.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GOLD_2 PF13897.1 ETO09748.1 - 0.88 9.7 4.5 1.9 8.7 3.1 1.5 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Neur_chan_memb PF02932.11 ETO09748.1 - 0.91 9.3 3.5 1.6 8.5 2.4 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region APC_CDC26 PF10471.4 ETO09748.1 - 2.6 8.8 19.9 4.3 8.1 11.7 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 FimP PF09766.4 ETO09748.1 - 2.7 6.9 16.2 5.2 6.0 11.2 1.4 1 0 0 1 1 1 0 Fms-interacting protein FCP1_C PF09309.5 ETO09748.1 - 3.2 6.9 14.3 5.5 6.2 9.9 1.3 1 0 0 1 1 1 0 FCP1, C-terminal LCD1 PF09798.4 ETO09748.1 - 4.5 5.1 9.7 2.3 6.1 5.1 1.6 2 0 0 2 2 2 0 DNA damage checkpoint protein PHD_3 PF13922.1 ETO09748.1 - 4.7 7.5 11.4 13 6.1 7.9 1.7 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx UPF0560 PF10577.4 ETO09748.1 - 5.6 5.0 11.2 8 4.5 7.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF3682 PF12446.3 ETO09748.1 - 8.3 6.7 21.8 15 5.9 15.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) FOP_dimer PF09398.5 ETO09749.1 - 4e-07 29.9 1.3 0.0002 21.2 0.1 3.0 1 1 0 2 2 2 2 FOP N terminal dimerisation domain Plasmodium_Vir PF05795.6 ETO09751.1 - 0.0086 15.3 3.8 0.0088 15.2 2.6 1.0 1 0 0 1 1 1 1 Plasmodium vivax Vir protein Suf PF05843.9 ETO09751.1 - 0.26 10.9 2.0 0.3 10.7 1.4 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SIR2 PF02146.12 ETO09752.1 - 3.8e-23 82.1 0.1 8e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 Sir2 family Podoplanin PF05808.6 ETO09752.1 - 0.46 10.0 2.5 20 4.7 2.4 2.5 2 0 0 2 2 2 0 Podoplanin YqfQ PF14181.1 ETO09752.1 - 3 7.8 11.2 6.1 6.8 7.8 1.4 1 0 0 1 1 1 0 YqfQ-like protein Claudin_2 PF13903.1 ETO09753.1 - 6.4 6.4 8.0 0.2 11.3 0.3 2.3 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Ribosomal_L9_N PF01281.14 ETO09754.1 - 1e-05 24.6 0.0 2.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.9 ETO09754.1 - 0.12 12.4 0.1 0.27 11.3 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L9, C-terminal domain UQ_con PF00179.21 ETO09755.1 - 1.2e-36 125.1 0.0 2.4e-36 124.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme F-box-like PF12937.2 ETO09755.1 - 0.095 12.4 0.1 0.44 10.3 0.1 2.3 1 1 0 1 1 1 0 F-box-like DHH PF01368.15 ETO09756.1 - 7e-07 28.9 0.0 4.6e-06 26.3 0.0 2.3 1 1 1 2 2 2 1 DHH family DHHA2 PF02833.9 ETO09756.1 - 0.00068 19.8 2.7 0.82 9.8 0.0 3.2 4 0 0 4 4 4 2 DHHA2 domain DUF1722 PF08349.6 ETO09756.1 - 0.022 14.6 1.9 0.26 11.1 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF2796 PF10986.3 ETO09756.1 - 0.12 12.3 6.8 2.5 8.0 1.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) B56 PF01603.15 ETO09758.1 - 3.9e-23 81.7 0.6 4.2e-23 81.6 0.4 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) B56 PF01603.15 ETO09759.1 - 4.4e-86 289.0 11.4 5.5e-82 275.5 2.1 2.0 1 1 1 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) DUF508 PF04370.7 ETO09759.1 - 0.043 13.4 0.1 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Annexin PF00191.15 ETO09760.1 - 1.5e-18 66.4 0.3 0.0021 17.9 0.0 4.3 4 0 0 4 4 4 4 Annexin Ras PF00071.17 ETO09761.1 - 0.00011 21.6 0.1 0.00011 21.6 0.0 1.7 2 0 0 2 2 2 1 Ras family Miro PF08477.8 ETO09761.1 - 0.018 15.5 1.2 0.049 14.1 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein Complex1_49kDa PF00346.14 ETO09761.1 - 0.075 12.0 1.8 3.6 6.5 0.0 2.2 2 0 0 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit FliP PF00813.15 ETO09761.1 - 0.17 11.5 2.2 4.1 7.0 0.0 2.2 2 0 0 2 2 2 0 FliP family EF-hand_1 PF00036.27 ETO09762.1 - 6.9e-25 84.4 18.6 3.7e-07 28.9 1.1 5.1 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 ETO09762.1 - 3e-22 78.5 6.8 4.5e-14 52.3 0.8 3.3 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 ETO09762.1 - 2.2e-18 64.4 16.9 4.4e-06 26.1 0.1 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 ETO09762.1 - 1.2e-17 62.3 20.3 2.2e-06 26.7 0.1 5.0 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 ETO09762.1 - 1.8e-11 43.4 14.1 0.00015 21.2 0.7 4.3 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.2 ETO09762.1 - 8.3e-07 28.7 1.9 0.017 14.8 0.0 3.6 3 1 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 ETO09762.1 - 0.00018 21.5 1.7 0.0023 17.9 0.0 2.9 2 1 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region DUF1388 PF07142.7 ETO09762.1 - 0.00095 18.8 3.8 0.00095 18.8 2.6 3.0 1 1 1 2 2 2 1 Repeat of unknown function (DUF1388) RRN3 PF05327.6 ETO09762.1 - 0.022 12.9 0.8 0.035 12.2 0.5 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Caleosin PF05042.8 ETO09762.1 - 0.041 13.4 0.2 0.34 10.4 0.0 2.6 3 0 0 3 3 3 0 Caleosin related protein Cytomega_UL84 PF06284.6 ETO09762.1 - 2 6.7 7.1 3 6.1 4.9 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein SOG2 PF10428.4 ETO09762.1 - 5 5.6 13.2 2.5 6.6 7.8 1.3 2 0 0 2 2 2 0 RAM signalling pathway protein CDC27 PF09507.5 ETO09762.1 - 7 5.7 35.7 8.8 5.4 24.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Arm PF00514.18 ETO09763.1 - 2.5e-13 49.2 7.1 1.1e-09 37.7 0.1 3.4 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 ETO09763.1 - 2.8e-08 33.9 0.5 0.00019 21.6 0.1 2.1 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 ETO09763.1 - 8.4e-05 22.9 0.1 0.0017 18.7 0.0 2.4 2 0 0 2 2 2 1 HEAT-like repeat HEAT PF02985.17 ETO09763.1 - 0.043 13.9 0.6 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 HEAT repeat WD40 PF00400.27 ETO09764.1 - 1.7e-77 252.7 21.3 1.9e-13 49.6 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO09764.1 - 4.1e-08 33.1 0.2 0.0042 16.8 0.0 3.7 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO09764.1 - 2.2e-06 26.0 5.5 0.017 13.2 0.1 3.8 2 2 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO09764.1 - 3.5e-05 22.7 8.3 0.4 9.3 0.0 4.8 1 1 1 3 3 3 2 Nup133 N terminal like PQQ_2 PF13360.1 ETO09764.1 - 7.4e-05 22.3 0.8 0.0062 16.0 0.5 3.0 1 1 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO09764.1 - 0.0011 17.3 2.3 0.25 9.5 0.2 3.0 2 1 1 3 3 3 3 Cytochrome D1 heme domain Hira PF07569.6 ETO09764.1 - 0.0021 17.2 0.3 4.8 6.3 0.0 3.9 2 1 3 5 5 5 1 TUP1-like enhancer of split Nbas_N PF15492.1 ETO09764.1 - 0.006 15.7 0.8 4.2 6.3 0.0 3.0 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Resistin PF06954.6 ETO09764.1 - 0.014 15.6 2.6 8.1 6.8 0.0 4.1 4 1 1 5 5 4 0 Resistin PD40 PF07676.7 ETO09764.1 - 0.015 14.9 1.5 9.3 6.0 0.0 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 ETO09764.1 - 0.061 12.3 0.6 5.6 5.9 0.0 3.0 2 2 2 4 4 4 0 Protein of unknown function (DUF1258) FmdE PF02663.9 ETO09764.1 - 0.084 12.7 0.4 8.3 6.3 0.1 2.6 1 1 1 3 3 3 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon CENP-T PF15511.1 ETO09766.1 - 0.006 15.8 19.2 0.0072 15.6 13.3 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CDC45 PF02724.9 ETO09766.1 - 0.045 11.7 27.8 0.063 11.3 19.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 ETO09766.1 - 0.096 11.1 28.5 0.15 10.5 19.8 1.3 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 ETO09766.1 - 0.11 10.4 43.9 0.0036 15.3 26.0 1.6 2 0 0 2 2 2 0 Nop14-like family Herpes_env PF01673.13 ETO09766.1 - 1.7 7.0 8.6 2.2 6.7 6.0 1.2 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein MDFI PF15316.1 ETO09766.1 - 9.9 6.1 10.7 1.5 8.8 4.3 1.7 1 1 1 2 2 2 0 MyoD family inhibitor Neur_chan_memb PF02932.11 ETO09767.1 - 0.092 12.6 1.6 0.14 12.0 1.1 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SR-25 PF10500.4 ETO09767.1 - 0.52 9.7 25.1 0.083 12.3 13.4 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein WD40 PF00400.27 ETO09768.1 - 1.3e-80 262.6 13.9 5.6e-13 48.2 0.1 7.0 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO09768.1 - 3.4e-13 49.7 1.8 1.3e-07 31.5 0.3 3.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO09768.1 - 2.5e-08 32.6 0.3 0.024 12.9 0.0 3.8 1 1 3 4 4 4 3 Cytochrome D1 heme domain Nup160 PF11715.3 ETO09768.1 - 1.5e-06 26.6 3.9 0.06 11.4 0.3 4.9 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO09768.1 - 6.6e-05 21.8 4.9 1.2 7.8 0.0 4.3 1 1 2 4 4 4 2 Nup133 N terminal like PD40 PF07676.7 ETO09768.1 - 0.00015 21.3 8.1 3.6 7.3 0.1 5.2 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO09768.1 - 0.0097 15.3 0.1 0.35 10.3 0.0 2.7 1 1 1 2 2 2 1 PQQ-like domain AcetylCoA_hyd_C PF13336.1 ETO09768.1 - 0.011 15.3 0.1 8.6 6.0 0.0 3.4 3 1 1 4 4 4 0 Acetyl-CoA hydrolase/transferase C-terminal domain DUF1258 PF06869.7 ETO09768.1 - 0.02 13.9 0.4 6.1 5.8 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1258) FmdE PF02663.9 ETO09768.1 - 0.022 14.6 1.6 0.25 11.2 0.1 2.5 1 1 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Mid2 PF04478.7 ETO09768.1 - 0.041 13.3 1.4 2.9 7.3 0.1 3.3 3 1 1 4 4 4 0 Mid2 like cell wall stress sensor HPS3_N PF14761.1 ETO09768.1 - 0.053 12.9 0.0 0.15 11.4 0.0 1.7 1 1 0 1 1 1 0 Hermansky-Pudlak syndrome 3 Cerato-platanin PF07249.7 ETO09768.1 - 0.077 13.0 0.2 16 5.4 0.0 2.7 2 1 0 2 2 2 0 Cerato-platanin zf-C2H2_4 PF13894.1 ETO09769.1 - 3.4e-11 42.6 56.7 0.00087 19.4 0.7 7.2 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2 PF00096.21 ETO09769.1 - 3.1e-10 39.7 52.8 0.0032 17.6 1.0 6.8 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETO09769.1 - 0.0012 19.0 6.0 0.0012 19.0 4.1 8.1 8 2 0 8 8 8 2 Zinc-finger double domain zf-met PF12874.2 ETO09769.1 - 0.28 11.4 0.2 0.28 11.4 0.1 5.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-Sec23_Sec24 PF04810.10 ETO09769.1 - 5.1 6.7 19.2 0.17 11.4 0.2 3.8 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger zinc_ribbon_5 PF13719.1 ETO09769.1 - 8.4 6.0 12.1 1.7 8.2 0.9 3.7 3 0 0 3 3 3 0 zinc-ribbon domain AAA_12 PF13087.1 ETO09770.1 - 0.0043 16.4 0.3 0.0083 15.5 0.2 1.4 1 0 0 1 1 1 1 AAA domain Dicty_CAR PF05462.6 ETO09771.1 - 0.00033 19.6 0.7 0.00033 19.6 0.5 1.5 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.16 ETO09771.1 - 0.00053 19.2 0.1 0.00074 18.7 0.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Ycf1 PF05758.7 ETO09771.1 - 0.0033 15.2 0.2 0.0042 14.8 0.1 1.1 1 0 0 1 1 1 1 Ycf1 DUF3311 PF11755.3 ETO09771.1 - 0.0039 16.7 3.9 0.0077 15.7 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3311) TRAP_alpha PF03896.11 ETO09771.1 - 0.0071 15.3 0.0 0.0088 15.0 0.0 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit SpoIIIAH PF12685.2 ETO09771.1 - 0.0087 15.5 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein PIG-P PF08510.7 ETO09771.1 - 0.024 14.2 6.8 0.034 13.7 0.0 2.7 2 1 1 3 3 3 0 PIG-P FAM176 PF14851.1 ETO09771.1 - 0.034 13.8 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 FAM176 family MpPF26 PF07666.6 ETO09771.1 - 0.036 13.9 0.3 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 M penetrans paralogue family 26 YMF19 PF02326.10 ETO09771.1 - 0.046 14.2 0.0 0.046 14.2 0.0 1.9 1 1 1 2 2 2 0 Plant ATP synthase F0 PBP1_TM PF14812.1 ETO09771.1 - 0.057 13.7 0.0 0.057 13.7 0.0 1.7 2 0 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4636 PF15468.1 ETO09771.1 - 0.099 12.0 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) DUF912 PF06024.7 ETO09771.1 - 0.29 11.1 0.0 0.29 11.1 0.0 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Chordopox_G3 PF06129.7 ETO09771.1 - 0.46 10.6 0.1 0.46 10.6 0.0 2.0 1 1 1 2 2 2 0 Chordopoxvirus G3 protein Git3_C PF11970.3 ETO09771.1 - 0.54 10.0 8.4 0.032 14.0 2.2 1.7 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term DUF4118 PF13493.1 ETO09771.1 - 0.72 10.0 7.4 1.2 9.3 2.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4118) PBP_sp32 PF07222.7 ETO09771.1 - 1.2 8.2 5.5 1.7 7.7 3.8 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CENP-B_dimeris PF09026.5 ETO09771.1 - 2.1 8.6 7.4 2.8 8.2 4.8 1.6 1 1 0 1 1 1 0 Centromere protein B dimerisation domain FixQ PF05545.6 ETO09771.1 - 2.6 7.7 6.0 2.5 7.8 0.7 2.6 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Nucleoplasmin PF03066.10 ETO09771.1 - 3.3 7.2 9.9 4.4 6.8 6.9 1.1 1 0 0 1 1 1 0 Nucleoplasmin TPR_17 PF13431.1 ETO09772.1 - 1.5e-10 40.4 1.5 1.7e-05 24.6 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO09772.1 - 1.7e-10 40.3 0.4 1.2e-05 24.8 0.1 2.3 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETO09772.1 - 5e-10 38.5 0.2 7.7e-06 25.3 0.0 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO09772.1 - 3.5e-08 32.7 0.0 0.0063 16.3 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO09772.1 - 5.8e-07 29.3 0.9 0.019 14.9 0.2 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO09772.1 - 1.7e-06 27.3 0.6 0.011 15.4 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO09772.1 - 0.00083 19.7 0.0 0.13 12.9 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO09772.1 - 0.0033 17.1 0.0 3 7.8 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.13 ETO09772.1 - 0.018 14.9 0.0 2.1 8.2 0.0 2.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.1 ETO09772.1 - 0.044 14.1 0.0 0.073 13.4 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETO09772.1 - 0.11 13.1 0.0 0.2 12.4 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat SNARE PF05739.14 ETO09773.1 - 1.1e-07 31.3 7.6 2.6e-07 30.2 5.3 1.7 1 0 0 1 1 1 1 SNARE domain TIR-like PF10137.4 ETO09773.1 - 0.037 13.6 0.3 0.069 12.7 0.2 1.4 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain DUF4365 PF14280.1 ETO09773.1 - 0.049 13.3 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4365) Phage_Gp23 PF10669.4 ETO09773.1 - 0.06 13.4 2.1 0.24 11.5 1.4 2.0 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Bac_globin PF01152.16 ETO09773.1 - 0.064 13.2 0.5 0.12 12.3 0.3 1.4 1 0 0 1 1 1 0 Bacterial-like globin DUF745 PF05335.8 ETO09773.1 - 0.39 10.2 14.7 0.1 12.1 3.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF2730 PF10805.3 ETO09773.1 - 1 9.1 4.2 0.82 9.4 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) adh_short PF00106.20 ETO09774.1 - 5e-16 59.0 0.0 1.6e-13 50.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 ETO09774.1 - 2.5e-07 30.7 0.0 4.7e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETO09774.1 - 1.6e-05 24.6 0.0 2.7e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETO09774.1 - 0.0027 17.1 0.0 0.0067 15.8 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family VD10_N PF08476.5 ETO09774.1 - 0.0045 16.4 0.1 3.4 7.1 0.1 2.8 2 0 0 2 2 2 2 Viral D10 N-terminal Methyltransf_18 PF12847.2 ETO09775.1 - 2.7e-09 37.5 0.0 6.3e-08 33.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO09775.1 - 7.2e-09 35.4 2.3 8.7e-09 35.1 0.3 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETO09775.1 - 4.9e-08 33.0 0.0 4.3e-07 29.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 ETO09775.1 - 2.7e-06 26.5 0.3 6.7e-06 25.2 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_12 PF08242.7 ETO09775.1 - 2.7e-06 27.7 0.1 3.7e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETO09775.1 - 2.8e-06 27.1 0.0 5.1e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 ETO09775.1 - 2.5e-05 23.7 0.6 8.8e-05 21.8 0.4 2.0 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_11 PF08241.7 ETO09775.1 - 3e-05 24.4 0.0 0.0027 18.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.15 ETO09775.1 - 0.00013 21.0 0.0 0.00023 20.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.1 ETO09775.1 - 0.00024 21.4 0.3 0.0019 18.5 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain MetW PF07021.7 ETO09775.1 - 0.0007 19.0 0.1 0.0017 17.7 0.1 1.6 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW CMAS PF02353.15 ETO09775.1 - 0.0013 17.8 0.7 0.014 14.4 0.5 2.2 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 ETO09775.1 - 0.0015 17.9 0.1 0.15 11.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_15 PF09445.5 ETO09775.1 - 0.0071 15.9 1.2 0.25 10.8 0.1 2.3 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_5 PF01795.14 ETO09775.1 - 0.0083 15.4 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 MraW methylase family Methyltransf_32 PF13679.1 ETO09775.1 - 0.021 14.4 0.1 0.074 12.7 0.0 1.9 3 0 0 3 3 3 0 Methyltransferase domain UPF0020 PF01170.13 ETO09775.1 - 0.035 13.6 0.0 0.07 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DUF2392 PF10288.4 ETO09775.1 - 0.1 12.9 1.7 0.26 11.6 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2392) DUF2194 PF09960.4 ETO09776.1 - 0.0052 14.8 3.0 0.0094 14.0 2.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2194) RsgI_N PF12791.2 ETO09776.1 - 0.063 12.9 0.2 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 Anti-sigma factor N-terminus DUF4391 PF14335.1 ETO09776.1 - 0.088 12.1 8.8 0.029 13.7 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4391) SR-25 PF10500.4 ETO09776.1 - 0.2 11.1 10.8 0.12 11.7 1.6 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein WBP-1 PF11669.3 ETO09776.1 - 1.3 9.1 6.1 0.17 11.9 0.2 2.4 2 1 0 2 2 2 0 WW domain-binding protein 1 Cut12 PF11500.3 ETO09776.1 - 2.3 7.8 12.9 0.055 13.1 3.1 2.1 2 0 0 2 2 2 0 Spindle pole body formation-associated protein DUF1713 PF08213.6 ETO09776.1 - 6.9 6.3 17.8 0.97 9.1 4.5 2.5 2 0 0 2 2 2 0 Mitochondrial domain of unknown function (DUF1713) YMF19 PF02326.10 ETO09776.1 - 7.5 7.2 7.9 0.8 10.3 1.0 2.5 2 1 0 2 2 2 0 Plant ATP synthase F0 PaREP1 PF05942.6 ETO09779.1 - 0.075 12.9 0.6 6.9 6.5 0.0 2.2 2 0 0 2 2 2 0 Archaeal PaREP1/PaREP8 family DUF2841 PF11001.3 ETO09779.1 - 0.18 11.7 8.9 0.41 10.5 4.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2841) AAA_21 PF13304.1 ETO09779.1 - 0.33 10.8 7.1 0.43 10.5 4.9 1.1 1 0 0 1 1 1 0 AAA domain DUF1104 PF06518.6 ETO09779.1 - 2.1 8.5 7.3 0.81 9.8 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1104) FAM216B PF15107.1 ETO09780.1 - 0.042 13.7 0.1 0.093 12.6 0.1 1.5 1 0 0 1 1 1 0 FAM216B protein family TEX19 PF15553.1 ETO09780.1 - 4 7.2 8.3 2.7 7.8 4.4 1.6 2 0 0 2 2 2 0 Testis-expressed protein 19 NIF PF03031.13 ETO09781.1 - 0.0031 17.1 0.0 0.008 15.8 0.0 1.7 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PBP_sp32 PF07222.7 ETO09781.1 - 0.019 14.1 0.4 0.032 13.4 0.2 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CAF-1_p150 PF11600.3 ETO09781.1 - 0.023 14.1 11.9 0.032 13.6 8.2 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4407 PF14362.1 ETO09782.1 - 1.9 7.3 11.8 3.2 6.6 8.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Vfa1 PF08432.5 ETO09782.1 - 2.2 8.2 32.8 0.018 15.0 14.3 2.7 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 OmpH PF03938.9 ETO09782.1 - 3.1 7.7 25.2 0.096 12.6 13.1 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Pyr_redox_2 PF07992.9 ETO09783.1 - 4.7e-20 72.3 0.0 6e-20 71.9 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETO09783.1 - 1.2e-12 48.2 0.0 1.5e-12 48.0 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETO09783.1 - 3.1e-10 40.3 0.8 8.3e-10 38.9 0.1 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETO09783.1 - 5e-07 28.9 0.0 6.9e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.14 ETO09783.1 - 0.095 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 ETO09783.1 - 0.11 12.4 0.1 9.5 6.3 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Oxidored_nitro PF00148.14 ETO09783.1 - 0.12 10.9 0.0 0.23 10.0 0.0 1.4 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase 3HCDH_N PF02737.13 ETO09783.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Orbi_NS3 PF01616.11 ETO09784.1 - 0.6 9.0 4.9 3.2 6.6 0.3 2.9 2 1 0 3 3 3 0 Orbivirus NS3 DUF3377 PF11857.3 ETO09784.1 - 1.1 8.9 6.7 0.83 9.3 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) DctQ PF04290.7 ETO09784.1 - 1.2 8.9 10.4 0.96 9.2 0.9 2.9 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component PH_11 PF15413.1 ETO09785.1 - 6.2e-11 42.5 0.6 6.2e-11 42.5 0.5 2.2 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 ETO09785.1 - 2.8e-07 30.6 4.2 1.3e-06 28.5 2.9 2.2 1 1 0 1 1 1 1 PH domain zf-TRAF PF02176.13 ETO09785.1 - 4.7e-05 23.6 7.1 0.00011 22.5 4.9 1.6 1 0 0 1 1 1 1 TRAF-type zinc finger PH_8 PF15409.1 ETO09785.1 - 0.0001 22.2 6.3 0.0073 16.3 0.1 3.1 4 0 0 4 4 4 2 Pleckstrin homology domain PH_9 PF15410.1 ETO09785.1 - 0.028 14.5 4.9 1.3 9.1 0.1 2.9 3 0 0 3 3 3 0 Pleckstrin homology domain DUF342 PF03961.8 ETO09785.1 - 0.58 8.5 4.8 0.96 7.7 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Jnk-SapK_ap_N PF09744.4 ETO09785.1 - 0.92 9.4 16.4 0.15 12.0 7.1 2.2 1 1 0 2 2 2 0 JNK_SAPK-associated protein-1 zf-Paramyx-P PF13008.2 ETO09788.1 - 0.09 11.9 3.9 0.21 10.8 2.7 1.6 1 0 0 1 1 1 0 Zinc-binding domain of Paramyxoviridae V protein DUF1129 PF06570.6 ETO09788.1 - 0.1 11.9 0.0 0.26 10.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF2448 PF10476.4 ETO09788.1 - 0.5 9.8 3.1 1.4 8.4 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2448) ABC_tran PF00005.22 ETO09790.1 - 9.9e-22 77.7 0.0 1.7e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.1 ETO09790.1 - 0.061 13.6 0.2 0.13 12.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 ETO09790.1 - 0.13 11.6 0.8 0.24 10.7 0.4 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain 7TM_GPCR_Sri PF10327.4 ETO09791.1 - 0.00047 19.2 0.6 0.00056 18.9 0.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri DUF4162 PF13732.1 ETO09791.1 - 0.042 14.3 1.6 0.38 11.2 1.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4162) Transketolase_C PF02780.15 ETO09792.1 - 3e-39 133.7 0.0 1e-38 132.0 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain Transket_pyr PF02779.19 ETO09792.1 - 0.014 14.9 0.0 0.028 13.9 0.0 1.5 2 0 0 2 2 2 0 Transketolase, pyrimidine binding domain cwf21 PF08312.7 ETO09793.1 - 0.00028 20.6 1.7 0.00067 19.4 1.2 1.7 1 0 0 1 1 1 1 cwf21 domain Pkinase PF00069.20 ETO09795.1 - 1.2e-38 132.8 0.2 2.5e-38 131.7 0.1 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO09795.1 - 6.1e-13 48.4 0.2 5.7e-06 25.5 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 ETO09795.1 - 0.034 13.8 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family HTH_Tnp_Tc3_2 PF01498.13 ETO09796.1 - 6.1e-05 22.9 0.3 0.00018 21.5 0.2 1.7 1 0 0 1 1 1 1 Transposase Aldedh PF00171.17 ETO09797.1 - 3.8e-69 233.2 0.0 7.9e-36 123.3 0.0 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.9 ETO09797.1 - 0.00026 19.8 0.0 0.00039 19.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) WD40 PF00400.27 ETO09798.1 - 3.6e-155 499.0 31.7 7.2e-12 44.7 0.1 16.7 15 1 1 16 16 16 16 WD domain, G-beta repeat NACHT PF05729.7 ETO09798.1 - 8.5e-11 41.7 0.0 3.4e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 NACHT domain Resistin PF06954.6 ETO09798.1 - 2.4e-06 27.7 0.3 2.1 8.6 0.0 6.2 3 1 2 5 5 5 1 Resistin Pentapeptide_4 PF13599.1 ETO09798.1 - 0.00011 21.9 2.0 0.00018 21.2 0.1 2.4 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETO09798.1 - 0.00042 19.4 0.6 0.0011 18.1 0.4 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) AAA_18 PF13238.1 ETO09798.1 - 0.0023 18.2 0.1 0.0023 18.2 0.0 3.9 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.1 ETO09798.1 - 0.0026 17.9 0.1 0.014 15.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain Pentapeptide_3 PF13576.1 ETO09798.1 - 0.0044 16.8 2.3 0.02 14.7 0.1 2.8 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) AAA_17 PF13207.1 ETO09798.1 - 0.027 15.2 0.0 0.16 12.8 0.0 2.4 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 ETO09799.1 - 8.9e-51 168.0 12.5 2.2e-10 40.0 0.1 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO09799.1 - 8.3e-11 40.7 0.1 0.00075 17.7 0.1 4.2 1 1 2 4 4 4 4 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO09799.1 - 3.7e-05 23.9 4.3 0.00017 21.9 2.8 2.4 1 1 0 1 1 1 1 TRAF-type zinc finger Symplekin_C PF12295.3 ETO09801.1 - 0.038 13.8 0.3 0.099 12.5 0.1 1.6 1 1 1 2 2 2 0 Symplekin tight junction protein C terminal Gal-3-0_sulfotr PF06990.6 ETO09801.1 - 0.091 11.4 0.6 0.12 11.0 0.4 1.2 1 0 0 1 1 1 0 Galactose-3-O-sulfotransferase TLD PF07534.11 ETO09803.1 - 2.1e-09 37.5 0.4 3.3e-09 36.8 0.2 1.3 1 0 0 1 1 1 1 TLD Pro_isomerase PF00160.16 ETO09804.1 - 1e-40 139.5 0.4 2.1e-40 138.4 0.3 1.5 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF506 PF04720.7 ETO09806.1 - 0.16 11.6 3.3 0.24 10.9 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Hydrolase_like PF13242.1 ETO09808.1 - 1.7e-08 34.0 0.0 2.9e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 ETO09808.1 - 5.6e-05 23.4 0.0 0.012 15.8 0.0 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 ETO09808.1 - 0.00016 21.9 0.1 0.00027 21.1 0.1 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase CelD_N PF02927.9 ETO09808.1 - 0.038 14.2 0.0 0.079 13.2 0.0 1.5 1 0 0 1 1 1 0 N-terminal ig-like domain of cellulase Hydrolase PF00702.21 ETO09808.1 - 0.05 14.0 0.0 0.27 11.6 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase RCC1 PF00415.13 ETO09809.1 - 4e-26 90.9 0.1 6.3e-11 42.3 0.0 5.3 5 1 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO09809.1 - 0.00097 18.6 12.7 0.097 12.3 0.0 4.4 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat TctB PF07331.6 ETO09809.1 - 0.092 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family TPR_12 PF13424.1 ETO09810.1 - 3.2e-31 107.0 1.7 8.5e-18 64.0 0.4 3.0 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO09810.1 - 6.1e-21 73.8 10.2 1.4e-10 40.6 0.5 3.3 2 1 2 4 4 4 3 TPR repeat TPR_10 PF13374.1 ETO09810.1 - 2.8e-20 71.5 0.0 7.9e-07 28.8 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO09810.1 - 5.7e-18 63.2 2.5 5.2e-08 32.0 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO09810.1 - 1.4e-17 62.4 9.2 3.5e-08 32.7 0.4 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO09810.1 - 1.5e-16 58.8 9.3 2.9e-08 32.9 0.4 4.0 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO09810.1 - 1.1e-15 56.1 5.9 8.5e-06 25.3 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO09810.1 - 5.1e-07 29.3 0.1 0.12 12.6 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO09810.1 - 0.00058 20.1 0.3 16 6.2 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETO09810.1 - 0.007 16.9 0.0 12 6.9 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 ETO09810.1 - 0.008 16.2 2.7 0.034 14.2 1.6 2.3 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.1 ETO09810.1 - 0.0097 15.0 0.3 0.37 9.9 0.1 2.9 3 1 0 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_3 PF07720.7 ETO09810.1 - 0.011 15.5 4.6 2.7 7.9 0.0 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat Parathyroid PF01279.12 ETO09810.1 - 0.017 15.7 1.3 0.13 12.8 0.1 2.5 1 1 1 2 2 2 0 Parathyroid hormone family Sel1 PF08238.7 ETO09810.1 - 0.019 15.6 0.6 12 6.7 0.0 3.2 3 0 0 3 3 3 0 Sel1 repeat TPR_16 PF13432.1 ETO09810.1 - 0.022 15.4 0.0 1.4 9.6 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat PPR PF01535.15 ETO09810.1 - 0.062 13.3 3.0 4.5 7.4 0.0 3.9 4 0 0 4 4 4 0 PPR repeat MIT PF04212.13 ETO09810.1 - 3.3 7.6 9.4 3.1 7.7 0.3 4.1 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain DUF3605 PF12239.3 ETO09811.1 - 1.6e-05 24.8 0.5 2.2e-05 24.3 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) LRR_6 PF13516.1 ETO09812.1 - 4.8e-12 44.6 9.3 0.011 15.6 0.0 7.6 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.2 ETO09812.1 - 0.0034 16.9 0.0 0.0034 16.9 0.0 4.1 2 1 2 4 4 4 1 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 ETO09812.1 - 0.0056 16.6 16.3 2.6 8.6 0.0 6.7 7 0 0 7 7 7 2 Leucine rich repeat LRR_8 PF13855.1 ETO09812.1 - 0.025 14.3 5.4 7.2 6.4 0.0 4.3 3 1 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.28 ETO09812.1 - 0.035 14.1 16.5 1.3 9.2 0.1 6.2 5 2 1 6 6 6 0 Leucine Rich Repeat Tcp10_C PF07202.8 ETO09812.1 - 0.12 11.8 0.1 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 T-complex protein 10 C-terminus Hira PF07569.6 ETO09813.1 - 0.18 11.0 1.6 0.19 10.9 0.6 1.5 1 1 0 1 1 1 0 TUP1-like enhancer of split IncA PF04156.9 ETO09814.1 - 0.008 15.7 0.9 0.008 15.7 0.6 1.7 2 0 0 2 2 2 1 IncA protein FAM176 PF14851.1 ETO09814.1 - 0.012 15.2 0.7 1.5 8.4 0.2 2.2 2 0 0 2 2 2 0 FAM176 family Ycf1 PF05758.7 ETO09814.1 - 0.045 11.4 0.1 0.069 10.8 0.1 1.3 1 0 0 1 1 1 0 Ycf1 DUF4131 PF13567.1 ETO09814.1 - 0.046 13.1 0.0 0.096 12.0 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) TRAP_alpha PF03896.11 ETO09814.1 - 0.061 12.3 1.8 0.32 9.9 1.1 1.9 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Selenoprotein_S PF06936.6 ETO09814.1 - 0.068 12.6 0.1 5.3 6.5 0.0 2.1 2 0 0 2 2 2 0 Selenoprotein S (SelS) NIF PF03031.13 ETO09814.1 - 0.22 11.1 2.2 0.5 10.0 1.5 1.6 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase WD40 PF00400.27 ETO09815.1 - 2.7e-63 207.7 13.4 6.5e-13 48.0 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO09815.1 - 1.2e-08 34.9 0.1 0.0013 18.4 0.0 2.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO09815.1 - 3.4e-06 25.5 2.2 0.097 10.7 0.0 3.9 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO09815.1 - 0.0022 16.7 6.0 0.28 9.9 4.3 3.4 1 1 1 2 2 2 2 Nup133 N terminal like Resistin PF06954.6 ETO09815.1 - 0.0036 17.5 0.6 7.9 6.8 0.1 3.8 2 1 2 4 4 4 1 Resistin DUF3312 PF11768.3 ETO09815.1 - 0.0064 14.7 0.1 0.043 12.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) Cytochrom_D1 PF02239.11 ETO09815.1 - 0.0071 14.6 1.0 0.26 9.5 0.0 2.9 3 1 1 4 4 4 1 Cytochrome D1 heme domain PD40 PF07676.7 ETO09815.1 - 0.57 9.9 5.7 22 4.8 0.0 4.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 ETO09816.1 - 1.3e-58 192.9 12.4 2.3e-11 43.0 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO09816.1 - 4.1e-06 25.2 4.1 0.2 9.7 0.0 5.0 1 1 4 5 5 5 3 Nucleoporin Nup120/160 PD40 PF07676.7 ETO09816.1 - 0.0015 18.1 1.0 14 5.4 0.0 4.4 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO09816.1 - 0.003 16.3 7.1 0.12 11.1 4.6 3.3 1 1 1 2 2 2 1 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO09816.1 - 0.016 13.5 0.4 0.11 10.7 0.1 2.2 1 1 1 2 2 2 0 Cytochrome D1 heme domain Me-amine-dh_H PF06433.6 ETO09816.1 - 0.02 13.5 0.1 0.41 9.2 0.0 2.7 2 1 1 4 4 4 0 Methylamine dehydrogenase heavy chain (MADH) PDDEXK_1 PF12705.2 ETO09816.1 - 0.56 9.5 1.8 15 4.8 0.0 2.5 1 1 1 2 2 2 0 PD-(D/E)XK nuclease superfamily Ras PF00071.17 ETO09817.1 - 3.4e-39 133.8 0.3 5.4e-38 129.9 0.2 2.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 ETO09817.1 - 1.8e-15 57.4 0.0 3.4e-14 53.3 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO09817.1 - 0.00014 21.1 0.1 0.00023 20.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETO09817.1 - 0.0012 18.7 0.1 0.0034 17.3 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase DivIC PF04977.10 ETO09818.1 - 0.0013 18.1 0.3 0.0013 18.1 0.2 9.5 5 4 3 9 9 9 5 Septum formation initiator BRE1 PF08647.6 ETO09818.1 - 0.003 17.4 8.0 0.003 17.4 5.5 7.4 3 2 3 6 6 6 2 BRE1 E3 ubiquitin ligase CENP-F_leu_zip PF10473.4 ETO09818.1 - 0.0035 17.2 16.4 0.0035 17.2 11.4 6.6 3 2 2 5 5 5 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CCDC155 PF14662.1 ETO09818.1 - 0.0057 16.2 15.2 0.0057 16.2 10.5 5.2 3 2 2 5 5 5 2 Coiled-coil region of CCDC155 IncA PF04156.9 ETO09818.1 - 0.0088 15.6 19.2 0.0088 15.6 13.3 6.2 3 2 2 5 5 5 1 IncA protein DUF3796 PF12676.2 ETO09818.1 - 0.13 12.4 8.4 0.58 10.3 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) DUF3584 PF12128.3 ETO09818.1 - 9.2 3.4 71.8 0.024 11.9 2.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) Kelch_6 PF13964.1 ETO09819.1 - 3.1e-09 36.6 2.3 3.2e-05 23.8 0.1 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO09819.1 - 0.00042 19.7 15.9 0.0062 16.0 0.4 4.7 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.1 ETO09819.1 - 0.003 17.4 6.4 0.33 10.9 1.0 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO09819.1 - 0.061 13.0 2.6 0.75 9.6 0.1 3.6 3 1 1 4 4 4 0 Galactose oxidase, central domain DUF3958 PF13125.1 ETO09819.1 - 0.11 12.3 2.6 0.25 11.2 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) Kelch_2 PF07646.10 ETO09819.1 - 0.42 10.4 6.3 11 6.0 0.2 4.2 5 1 0 5 5 5 0 Kelch motif DUF1675 PF07897.6 ETO09820.1 - 0.27 11.0 12.3 0.3 10.9 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF1390 PF07150.6 ETO09820.1 - 0.32 10.3 11.8 0.42 9.9 8.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) SMN PF06003.7 ETO09820.1 - 1.6 7.8 10.7 1.9 7.4 7.4 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) FAM60A PF15396.1 ETO09820.1 - 1.7 8.3 9.5 2.3 7.9 6.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Menin PF05053.8 ETO09820.1 - 2.3 6.3 13.7 2.6 6.0 9.5 1.1 1 0 0 1 1 1 0 Menin Apis_Csd PF11671.3 ETO09820.1 - 9 6.0 19.1 14 5.4 13.2 1.4 1 0 0 1 1 1 0 Complementary sex determiner protein PARG_cat PF05028.9 ETO09821.1 - 6e-28 98.0 9.5 8.1e-28 97.6 6.6 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) adh_short PF00106.20 ETO09828.1 - 2.7e-13 50.1 0.0 4.1e-11 43.0 0.0 2.9 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETO09828.1 - 1.6e-06 28.1 0.1 2.5e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETO09828.1 - 1.8e-06 27.7 0.0 2.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 ETO09828.1 - 0.00027 19.9 0.0 0.00042 19.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 ETO09828.1 - 0.0014 18.1 0.0 0.0023 17.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETO09828.1 - 0.0047 15.6 0.1 0.0075 15.0 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_Gly3P_dh_N PF01210.18 ETO09828.1 - 0.016 14.9 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF4355 PF14265.1 ETO09829.1 - 0.062 13.2 12.0 0.092 12.6 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) DUF1682 PF07946.9 ETO09829.1 - 1.9 7.2 11.9 2.1 7.1 8.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1682) DHHW PF14286.1 ETO09830.1 - 0.03 13.6 9.5 0.043 13.1 6.6 1.2 1 0 0 1 1 1 0 DHHW protein DUF2514 PF10721.4 ETO09830.1 - 5.9 6.5 14.7 1 9.0 6.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2514) DUF3251 PF11622.3 ETO09830.1 - 6.3 6.1 11.4 0.13 11.6 1.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3251) HHA PF05321.6 ETO09830.1 - 6.3 7.0 6.8 0.66 10.1 0.5 2.5 3 0 0 3 3 3 0 Haemolysin expression modulating protein YjcZ PF13990.1 ETO09830.1 - 7.8 5.5 9.8 3.3 6.7 4.9 1.7 1 1 1 2 2 2 0 YjcZ-like protein DUF1515 PF07439.6 ETO09831.1 - 0.00051 19.8 2.2 0.00051 19.8 1.5 2.9 3 1 0 3 3 3 1 Protein of unknown function (DUF1515) Trans_reg_C PF00486.23 ETO09831.1 - 0.035 14.0 1.6 0.27 11.1 0.1 2.8 2 1 0 2 2 2 0 Transcriptional regulatory protein, C terminal DUF972 PF06156.8 ETO09831.1 - 2.5 8.5 23.3 0.24 11.7 3.6 4.1 2 2 2 4 4 4 0 Protein of unknown function (DUF972) WD40 PF00400.27 ETO09832.1 - 3.1e-56 185.3 24.9 3e-10 39.5 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO09832.1 - 9.8e-13 47.0 7.5 0.02 13.0 0.8 6.2 1 1 4 5 5 5 5 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO09832.1 - 3e-07 30.7 1.4 1e-06 28.9 0.9 2.0 1 0 0 1 1 1 1 TRAF-type zinc finger DUF2774 PF11242.3 ETO09832.1 - 0.24 11.4 3.0 0.44 10.5 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Acyl-CoA_dh_N PF02771.11 ETO09833.1 - 1.1e-12 48.5 0.0 1.8e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Zn-ribbon_8 PF09723.5 ETO09834.1 - 0.042 13.8 0.0 0.098 12.6 0.0 1.7 1 0 0 1 1 1 0 Zinc ribbon domain BRCT PF00533.21 ETO09834.1 - 1.4 9.0 7.5 0.89 9.7 0.7 2.8 2 1 1 3 3 3 0 BRCA1 C Terminus (BRCT) domain OST3_OST6 PF04756.8 ETO09836.1 - 3.7e-11 42.8 0.4 7e-11 41.9 0.3 1.4 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 ETO09836.1 - 0.063 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Tetraspannin PF00335.15 ETO09836.1 - 0.12 11.5 2.9 0.75 9.0 0.2 2.1 2 0 0 2 2 2 0 Tetraspanin family DUF4234 PF14018.1 ETO09836.1 - 0.13 12.0 0.3 0.13 12.0 0.2 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4234) Kinesin PF00225.18 ETO09837.1 - 2e-15 56.3 0.3 2.1e-15 56.2 0.2 1.0 1 0 0 1 1 1 1 Kinesin motor domain Ribosomal_S7e PF01251.13 ETO09837.1 - 0.044 13.2 0.0 0.044 13.2 0.0 1.0 1 0 0 1 1 1 0 Ribosomal protein S7e Shisa PF13908.1 ETO09838.1 - 7.8e-05 22.9 0.4 0.00012 22.3 0.3 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator WEMBL PF05701.6 ETO09838.1 - 8.3e-05 21.2 7.7 0.00012 20.7 5.3 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Myosin_tail_1 PF01576.14 ETO09838.1 - 0.00012 19.9 10.8 0.00015 19.6 7.5 1.1 1 0 0 1 1 1 1 Myosin tail ABC2_membrane_3 PF12698.2 ETO09838.1 - 0.034 13.1 0.0 0.058 12.4 0.0 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_27 PF13514.1 ETO09838.1 - 0.041 11.5 8.0 0.055 11.1 5.5 1.1 1 0 0 1 1 1 0 AAA domain IFT57 PF10498.4 ETO09838.1 - 0.07 11.8 8.8 0.097 11.3 6.1 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 IncA PF04156.9 ETO09838.1 - 0.099 12.2 15.0 0.19 11.2 10.4 1.5 1 0 0 1 1 1 0 IncA protein FAM163 PF15069.1 ETO09838.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 FAM163 family GAS PF13851.1 ETO09838.1 - 0.11 11.6 12.6 0.26 10.4 7.7 2.1 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 ETO09838.1 - 0.12 11.0 9.2 0.22 10.1 6.3 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.1 ETO09838.1 - 0.14 11.1 1.8 0.29 10.0 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) OmpH PF03938.9 ETO09838.1 - 0.15 12.0 8.3 0.27 11.1 5.8 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) COG2 PF06148.6 ETO09838.1 - 0.25 11.2 5.0 0.51 10.2 1.0 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4446 PF14584.1 ETO09838.1 - 0.27 11.0 8.0 0.23 11.2 1.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) HrpB7 PF09486.5 ETO09838.1 - 0.29 11.0 6.2 1 9.2 4.3 2.0 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF745 PF05335.8 ETO09838.1 - 0.33 10.4 6.1 0.44 10.0 1.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Med4 PF10018.4 ETO09838.1 - 0.38 10.1 7.4 0.78 9.1 5.1 1.5 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 K-box PF01486.12 ETO09838.1 - 0.47 10.2 8.0 4.6 7.1 5.6 2.5 1 1 0 1 1 1 0 K-box region FliJ PF02050.11 ETO09838.1 - 0.63 10.1 14.5 0.26 11.3 2.6 2.4 1 1 1 2 2 2 0 Flagellar FliJ protein Laminin_II PF06009.7 ETO09838.1 - 0.67 9.7 6.3 1.9 8.2 4.3 1.8 1 0 0 1 1 1 0 Laminin Domain II FlaC_arch PF05377.6 ETO09838.1 - 0.67 9.8 8.0 4.5 7.2 1.1 3.8 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) APG6 PF04111.7 ETO09838.1 - 0.69 8.8 12.7 1 8.3 8.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Tropomyosin_1 PF12718.2 ETO09838.1 - 0.94 9.3 15.8 3.7 7.4 10.7 2.1 1 1 0 1 1 1 0 Tropomyosin like DUF4515 PF14988.1 ETO09838.1 - 0.96 9.0 17.2 0.072 12.7 1.8 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4515) NPV_P10 PF05531.7 ETO09838.1 - 0.97 9.7 4.5 5.3 7.3 0.2 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Laminin_I PF06008.9 ETO09838.1 - 1.1 8.4 12.6 1.6 8.0 5.9 2.1 1 1 1 2 2 2 0 Laminin Domain I DUF972 PF06156.8 ETO09838.1 - 1.3 9.4 14.7 0.33 11.3 1.3 2.7 2 1 1 3 3 2 0 Protein of unknown function (DUF972) DUF3847 PF12958.2 ETO09838.1 - 1.7 8.4 8.6 8.4 6.2 0.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) DUF3391 PF11871.3 ETO09838.1 - 2 8.6 6.1 1.4 9.1 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Fib_alpha PF08702.5 ETO09838.1 - 2.1 8.4 6.9 5 7.2 4.8 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.7 ETO09838.1 - 2.2 8.0 11.8 5.4 6.7 7.9 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein FlxA PF14282.1 ETO09838.1 - 3 7.8 9.8 5.7 6.9 6.2 2.0 1 1 0 1 1 1 0 FlxA-like protein GrpE PF01025.14 ETO09838.1 - 4.1 6.9 11.7 1.9 8.0 4.9 2.2 1 1 1 2 2 2 0 GrpE DUF3552 PF12072.3 ETO09838.1 - 5.5 6.1 13.4 6.5 5.9 8.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) CTNNB1_binding PF08347.6 ETO09838.1 - 5.9 7.0 8.7 7.7 6.7 0.4 2.1 2 0 0 2 2 2 0 N-terminal CTNNB1 binding Spc24 PF08286.6 ETO09838.1 - 6.3 6.5 13.2 12 5.5 1.1 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 CENP-F_leu_zip PF10473.4 ETO09838.1 - 7.5 6.4 16.2 8.4 6.2 9.4 2.3 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Kelch_4 PF13418.1 ETO09840.1 - 0.053 13.3 0.2 0.35 10.6 0.0 2.5 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO09840.1 - 0.081 13.1 1.1 3.7 7.8 0.0 3.4 5 0 0 5 5 5 0 Kelch motif ubiquitin PF00240.18 ETO09841.1 - 1e-26 92.0 1.0 1.5e-26 91.5 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 ETO09841.1 - 4.1e-13 48.8 0.5 4.1e-13 48.8 0.3 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 ETO09841.1 - 0.00014 22.0 0.3 0.00078 19.6 0.2 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 ETO09841.1 - 0.043 13.7 0.2 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Ogr_Delta PF04606.7 ETO09842.1 - 0.18 11.4 1.0 0.6 9.8 0.4 2.1 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger BCHF PF07284.6 ETO09843.1 - 0.82 9.5 4.1 1.8 8.4 1.5 2.2 1 1 1 2 2 2 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) Xin PF08043.7 ETO09844.1 - 0.03 14.0 1.4 4.2 7.2 0.2 2.7 2 0 0 2 2 2 0 Xin repeat Ycf1 PF05758.7 ETO09845.1 - 0.081 10.6 10.8 0.081 10.6 7.5 1.0 1 0 0 1 1 1 0 Ycf1 Hom_end_hint PF05203.11 ETO09845.1 - 0.11 12.2 5.1 0.12 12.0 3.5 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint OATP PF03137.15 ETO09845.1 - 0.94 7.4 4.8 1.1 7.2 3.3 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family UvrD-helicase PF00580.16 ETO09845.1 - 1.3 8.1 10.5 1.6 7.9 7.2 1.0 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Glyco_transf_15 PF01793.11 ETO09845.1 - 2.7 6.8 8.6 3.2 6.6 6.0 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase YqfQ PF14181.1 ETO09845.1 - 4.5 7.2 14.7 7 6.6 10.2 1.3 1 0 0 1 1 1 0 YqfQ-like protein AIF_C PF14721.1 ETO09845.1 - 5.1 7.3 7.6 8 6.7 5.3 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Sigma70_r1_1 PF03979.9 ETO09846.1 - 0.01 15.7 0.1 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 Peptidase_S10 PF00450.17 ETO09847.1 - 1.4e-28 100.2 3.7 3.8e-28 98.7 2.6 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase hEGF PF12661.2 ETO09848.1 - 0.0052 16.7 3.7 0.015 15.3 2.6 1.8 1 0 0 1 1 1 1 Human growth factor-like EGF EGF_2 PF07974.8 ETO09848.1 - 0.019 15.0 1.5 0.019 15.0 1.0 2.4 2 0 0 2 2 2 0 EGF-like domain O-ag_pol_Wzy PF14296.1 ETO09848.1 - 0.04 12.5 1.0 0.15 10.5 0.2 2.0 2 0 0 2 2 2 0 O-antigen polysaccharide polymerase Wzy CD34_antigen PF06365.7 ETO09848.1 - 0.098 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Laminin_EGF PF00053.19 ETO09848.1 - 0.33 10.9 4.8 0.31 10.9 0.2 2.5 2 0 0 2 2 2 0 Laminin EGF-like (Domains III and V) Chalcone PF02431.10 ETO09849.1 - 0.0062 15.9 0.5 0.0062 15.9 0.3 1.6 2 0 0 2 2 2 1 Chalcone-flavanone isomerase AbiH PF14253.1 ETO09849.1 - 0.039 13.5 7.4 0.047 13.2 5.2 1.2 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH DNA_pol_lambd_f PF10391.4 ETO09849.1 - 0.072 12.6 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda TMPIT PF07851.8 ETO09850.1 - 2.7e-26 92.4 11.4 2.7e-26 92.4 7.9 1.7 2 0 0 2 2 2 1 TMPIT-like protein tRNA_U5-meth_tr PF05958.6 ETO09850.1 - 0.002 16.9 0.6 0.0033 16.1 0.4 1.3 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase DUF3464 PF11947.3 ETO09853.1 - 0.029 13.8 0.3 0.055 12.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) LicD PF04991.8 ETO09853.1 - 5.6 7.0 14.7 0.43 10.6 3.5 2.6 2 1 1 3 3 3 0 LicD family DUF4149 PF13664.1 ETO09854.1 - 0.042 13.9 1.2 0.11 12.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) Fer4_NifH PF00142.13 ETO09854.1 - 0.042 13.0 0.2 0.076 12.1 0.2 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AA_permease_C PF13906.1 ETO09854.1 - 0.21 11.4 0.1 0.21 11.4 0.1 2.4 3 0 0 3 3 3 0 C-terminus of AA_permease UPF0118 PF01594.11 ETO09854.1 - 7.5 5.4 10.3 0.13 11.2 1.6 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF20 PUB PF09409.5 ETO09856.1 - 0.00096 18.8 2.3 0.0061 16.2 1.6 2.3 1 1 0 1 1 1 1 PUB domain Clathrin_propel PF01394.15 ETO09856.1 - 0.048 13.9 0.3 0.57 10.5 0.0 2.7 2 0 0 2 2 2 0 Clathrin propeller repeat DUF3874 PF12990.2 ETO09856.1 - 0.08 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknonw function from B. Theta Gene description (DUF3874) Spc7 PF08317.6 ETO09857.1 - 0.0072 15.0 2.2 0.0089 14.7 1.6 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Prominin PF05478.6 ETO09857.1 - 0.012 13.1 1.6 0.017 12.7 1.1 1.1 1 0 0 1 1 1 0 Prominin IFT57 PF10498.4 ETO09857.1 - 0.027 13.2 2.9 0.039 12.6 2.0 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 BLOC1_2 PF10046.4 ETO09857.1 - 0.03 14.4 3.7 0.045 13.8 2.6 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 EzrA PF06160.7 ETO09857.1 - 0.033 12.4 4.7 0.044 11.9 3.3 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA NPV_P10 PF05531.7 ETO09857.1 - 0.033 14.4 2.7 0.075 13.2 1.9 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF3552 PF12072.3 ETO09857.1 - 0.034 13.3 7.6 0.085 12.0 5.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Cep57_MT_bd PF06657.8 ETO09857.1 - 0.073 13.0 3.9 0.15 12.0 0.2 2.1 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Fib_alpha PF08702.5 ETO09857.1 - 0.077 13.1 3.4 0.11 12.6 2.4 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family APG6 PF04111.7 ETO09857.1 - 0.082 11.9 4.8 0.1 11.6 3.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4618 PF15397.1 ETO09857.1 - 0.083 12.2 4.0 0.11 11.7 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DivIC PF04977.10 ETO09857.1 - 0.14 11.6 5.4 0.13 11.7 2.7 1.8 1 1 0 1 1 1 0 Septum formation initiator DUF4110 PF13422.1 ETO09857.1 - 0.14 12.0 2.4 0.26 11.1 1.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4110) DUF4164 PF13747.1 ETO09857.1 - 0.15 12.2 3.1 0.31 11.1 2.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Fzo_mitofusin PF04799.8 ETO09857.1 - 0.2 11.0 5.2 0.52 9.6 1.3 2.0 2 0 0 2 2 2 0 fzo-like conserved region DUF3053 PF11254.3 ETO09857.1 - 0.21 10.8 2.9 0.18 11.0 1.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3053) FlaC_arch PF05377.6 ETO09857.1 - 0.29 11.0 2.7 0.5 10.2 1.5 1.7 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) YgaB PF14182.1 ETO09857.1 - 0.55 10.5 5.1 0.81 9.9 3.2 1.5 1 1 0 1 1 1 0 YgaB-like protein FUN14 PF04930.10 ETO09857.1 - 4.6 7.5 6.9 46 4.3 4.8 2.4 1 1 0 1 1 1 0 FUN14 family TMF_DNA_bd PF12329.3 ETO09857.1 - 9.8 6.0 11.3 1.9 8.3 3.7 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Peptidase_M22 PF00814.20 ETO09858.1 - 0.014 14.9 0.0 0.017 14.6 0.0 1.1 1 0 0 1 1 1 0 Glycoprotease family BcrAD_BadFG PF01869.15 ETO09858.1 - 0.032 13.5 0.0 0.043 13.1 0.0 1.1 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family WD40 PF00400.27 ETO09860.1 - 2.2e-59 195.3 14.2 1.3e-11 43.9 0.7 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO09860.1 - 2.8e-10 38.9 5.8 0.0048 15.1 0.0 5.0 1 1 2 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO09860.1 - 0.00074 18.3 10.9 2.4 6.8 0.9 5.0 1 1 4 5 5 5 3 Nup133 N terminal like RED_C PF07807.6 ETO09860.1 - 0.013 15.6 0.8 27 4.9 0.0 3.7 3 1 1 4 4 4 0 RED-like protein C-terminal region USP7_C2 PF14533.1 ETO09860.1 - 0.058 12.8 0.4 0.88 8.9 0.0 2.8 2 1 0 2 2 2 0 Ubiquitin-specific protease C-terminal Kelch_6 PF13964.1 ETO09860.1 - 0.55 10.5 10.8 6.4 7.1 0.2 5.0 4 1 0 5 5 5 0 Kelch motif UPF0220 PF05255.6 ETO09861.1 - 0.029 13.6 2.4 0.79 8.9 0.1 3.1 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0220) Trep_Strep PF09605.5 ETO09861.1 - 2.5 7.7 11.4 0.099 12.3 2.0 2.4 1 1 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF1388 PF07142.7 ETO09862.1 - 0.0026 17.4 3.5 0.0026 17.4 2.4 2.1 2 0 0 2 2 2 1 Repeat of unknown function (DUF1388) Merozoite_SPAM PF07133.6 ETO09862.1 - 1.9 8.3 25.9 3.1 7.6 17.9 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Trypan_PARP PF05887.6 ETO09862.1 - 3.6 7.3 16.1 5 6.9 11.2 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SeqA PF03925.8 ETO09862.1 - 4.1 7.0 14.7 5.5 6.6 10.2 1.4 1 0 0 1 1 1 0 SeqA protein CDC45 PF02724.9 ETO09862.1 - 6 4.7 28.0 6.9 4.5 19.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Raftlin PF15250.1 ETO09862.1 - 6.1 5.2 18.6 7.7 4.9 12.9 1.3 1 0 0 1 1 1 0 Raftlin DUF913 PF06025.7 ETO09862.1 - 9.9 4.7 11.0 12 4.5 7.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PCYCGC PF13798.1 ETO09863.1 - 0.28 10.8 2.5 0.24 11.1 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function with PCYCGC motif DUF1846 PF08903.6 ETO09864.1 - 0.0078 14.7 0.4 0.0096 14.4 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1846) DUF1184 PF06683.6 ETO09864.1 - 0.0096 15.5 1.3 0.011 15.3 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1184) DUF1850 PF08905.6 ETO09864.1 - 0.021 14.6 0.1 0.053 13.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1850) AAA_12 PF13087.1 ETO09866.1 - 1e-56 191.5 0.0 2.2e-56 190.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 ETO09866.1 - 6.7e-43 146.9 2.4 1.6e-23 83.4 0.2 2.4 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 ETO09866.1 - 2.1e-13 49.8 0.0 7.7e-11 41.5 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 ETO09866.1 - 2.3e-13 50.1 0.0 9.7e-13 48.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.16 ETO09866.1 - 2e-08 33.8 0.0 1.1e-05 24.9 0.0 2.5 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain PhoH PF02562.11 ETO09866.1 - 2.6e-07 30.0 0.1 0.00073 18.8 0.1 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_22 PF13401.1 ETO09866.1 - 2.2e-06 27.8 0.1 7.2e-05 22.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.4 ETO09866.1 - 3.2e-05 23.0 0.5 0.00042 19.3 0.0 2.7 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 ETO09866.1 - 0.00015 21.3 0.0 1.9 7.9 0.0 3.3 2 1 1 3 3 3 1 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 ETO09866.1 - 0.00024 20.6 0.1 0.001 18.5 0.1 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_17 PF13207.1 ETO09866.1 - 0.0004 21.1 0.0 0.0014 19.3 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA PF00004.24 ETO09866.1 - 0.00058 20.0 0.2 0.0017 18.5 0.0 2.0 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 ETO09866.1 - 0.0012 18.7 0.1 0.058 13.2 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PIF1 PF05970.9 ETO09866.1 - 0.0013 17.7 0.4 0.016 14.1 0.3 2.3 1 1 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.1 ETO09866.1 - 0.0034 17.3 0.0 0.011 15.7 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.21 ETO09866.1 - 0.0038 16.7 0.1 0.0095 15.4 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain Zeta_toxin PF06414.7 ETO09866.1 - 0.0051 15.9 0.0 0.011 14.8 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin IstB_IS21 PF01695.12 ETO09866.1 - 0.0095 15.3 0.0 0.036 13.5 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.1 ETO09866.1 - 0.01 16.1 0.0 0.05 13.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain fn1 PF00039.13 ETO09866.1 - 0.016 14.9 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 Fibronectin type I domain Helicase_RecD PF05127.9 ETO09866.1 - 0.022 14.4 0.0 0.065 12.8 0.0 1.8 1 0 0 1 1 1 0 Helicase T2SE PF00437.15 ETO09866.1 - 0.022 13.6 0.2 0.038 12.8 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Response_reg PF00072.19 ETO09866.1 - 0.023 14.6 0.0 0.08 12.9 0.0 1.9 2 0 0 2 2 1 0 Response regulator receiver domain AAA_25 PF13481.1 ETO09866.1 - 0.034 13.5 0.0 0.11 11.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain RuvB_N PF05496.7 ETO09866.1 - 0.041 12.9 0.0 0.11 11.5 0.0 1.7 2 0 0 2 2 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 ETO09866.1 - 0.056 13.1 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 ETO09866.1 - 0.056 12.5 0.0 0.099 11.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SMC_N PF02463.14 ETO09866.1 - 0.061 12.5 0.1 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_33 PF13671.1 ETO09866.1 - 0.082 12.7 0.1 0.34 10.7 0.0 2.0 2 1 0 2 2 1 0 AAA domain Mgm101p PF06420.7 ETO09866.1 - 0.11 11.8 0.2 0.65 9.2 0.0 2.2 3 0 0 3 3 3 0 Mitochondrial genome maintenance MGM101 EF-hand_6 PF13405.1 ETO09867.1 - 1.3e-10 40.1 1.5 1.8e-05 24.2 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 ETO09867.1 - 3.5e-10 39.8 3.8 1.9e-09 37.5 0.9 2.8 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO09867.1 - 1.1e-09 36.8 1.0 3.5e-06 25.9 0.1 3.0 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 ETO09867.1 - 5.6e-08 32.2 2.6 0.00084 18.9 0.2 2.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 ETO09867.1 - 0.00026 20.2 0.3 0.00026 20.2 0.2 2.2 2 0 0 2 2 2 1 EF hand Cauli_DNA-bind PF03310.8 ETO09867.1 - 0.0074 16.1 1.1 0.028 14.2 0.8 1.9 2 0 0 2 2 2 1 Caulimovirus DNA-binding protein UAA PF08449.6 ETO09868.1 - 3.2e-41 141.2 23.4 1.5e-39 135.7 11.4 2.2 2 0 0 2 2 2 2 UAA transporter family Na_trans_assoc PF06512.8 ETO09868.1 - 2.5 8.0 5.8 1.5 8.7 0.7 2.0 2 0 0 2 2 2 0 Sodium ion transport-associated V-ATPase_C PF03223.10 ETO09869.1 - 2.6e-79 266.8 3.5 3.7e-79 266.3 2.4 1.2 1 0 0 1 1 1 1 V-ATPase subunit C Sipho_Gp157 PF05565.6 ETO09869.1 - 0.0032 17.0 1.9 0.0032 17.0 1.3 2.9 3 1 0 3 3 3 1 Siphovirus Gp157 Zip PF02535.17 ETO09869.1 - 9.3 5.1 6.5 14 4.6 4.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SPX PF03105.14 ETO09870.1 - 1.5e-19 70.8 26.4 1.7e-18 67.3 18.3 2.1 1 1 0 1 1 1 1 SPX domain Rad21_Rec8_N PF04825.8 ETO09870.1 - 0.017 15.0 0.2 0.041 13.8 0.1 1.7 1 0 0 1 1 1 0 N terminus of Rad21 / Rec8 like protein Tox-PL-2 PF15643.1 ETO09870.1 - 0.036 14.0 3.2 0.5 10.3 0.9 2.5 1 1 1 2 2 2 0 Papain fold toxin 2 DUF2573 PF10835.3 ETO09870.1 - 0.069 13.2 4.4 0.34 10.9 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2573) DUF1018 PF06252.7 ETO09870.1 - 0.09 13.2 0.3 0.09 13.2 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1018) Glu_syn_central PF04898.9 ETO09871.1 - 0.06 12.6 0.2 0.07 12.3 0.1 1.1 1 0 0 1 1 1 0 Glutamate synthase central domain SID-1_RNA_chan PF13965.1 ETO09872.1 - 0.014 13.5 0.8 0.017 13.3 0.5 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Cwf_Cwc_15 PF04889.7 ETO09872.1 - 0.1 12.2 12.1 0.19 11.4 8.1 1.6 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 ETO09872.1 - 0.95 7.4 9.7 0.097 10.6 3.3 1.6 2 0 0 2 2 2 0 CDC45-like protein GATase_3 PF07685.9 ETO09872.1 - 3.7 7.1 7.8 11 5.5 5.4 1.8 1 1 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain UBA_4 PF14555.1 ETO09873.1 - 1.4e-07 30.8 0.0 2.5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain CYTL1 PF15153.1 ETO09873.1 - 0.1 12.2 0.8 0.21 11.2 0.6 1.5 1 0 0 1 1 1 0 Cytokine-like protein 1 DUF2681 PF10883.3 ETO09874.1 - 0.03 14.5 0.2 0.03 14.5 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) SAM_1 PF00536.25 ETO09874.1 - 0.065 13.4 0.1 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF3091 PF11291.3 ETO09875.1 - 6.8 6.7 9.4 1.2 9.1 3.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3091) DUF940 PF06082.6 ETO09876.1 - 0.053 12.0 1.1 0.056 12.0 0.8 1.1 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) Vps52 PF04129.7 ETO09877.1 - 1.4e-26 93.1 3.2 2e-26 92.6 2.2 1.1 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 ETO09877.1 - 4.3e-07 28.4 7.1 6e-07 28.0 4.9 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Myosin_tail_1 PF01576.14 ETO09877.1 - 0.0011 16.7 4.6 0.0014 16.4 3.2 1.1 1 0 0 1 1 1 1 Myosin tail COG2 PF06148.6 ETO09877.1 - 0.0063 16.3 6.7 0.02 14.7 4.6 1.9 1 1 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Laminin_II PF06009.7 ETO09877.1 - 0.0073 16.0 4.9 0.008 15.9 1.0 2.2 1 1 1 2 2 2 1 Laminin Domain II IncA PF04156.9 ETO09877.1 - 0.022 14.3 8.2 0.033 13.8 5.7 1.3 1 1 0 1 1 1 0 IncA protein IFT57 PF10498.4 ETO09877.1 - 0.026 13.2 11.2 0.018 13.8 6.6 1.5 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 GatB_Yqey PF02637.13 ETO09877.1 - 0.038 13.7 1.5 0.054 13.2 0.5 1.6 1 1 0 1 1 1 0 GatB domain DUF3829 PF12889.2 ETO09877.1 - 0.038 13.1 1.6 0.049 12.8 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) COG5 PF10392.4 ETO09877.1 - 0.065 13.1 7.5 0.077 12.9 4.5 1.6 1 1 1 2 2 2 0 Golgi transport complex subunit 5 UPF0240 PF06784.6 ETO09877.1 - 0.072 12.7 1.6 0.12 12.0 0.8 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0240) Cob_adeno_trans PF01923.13 ETO09877.1 - 0.076 12.7 1.5 0.12 12.1 0.7 1.5 1 1 0 1 1 1 0 Cobalamin adenosyltransferase Lzipper-MIP1 PF14389.1 ETO09877.1 - 0.23 11.5 3.5 0.53 10.4 0.2 2.8 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 YlbD_coat PF14071.1 ETO09877.1 - 0.27 11.3 10.1 4.8 7.2 0.1 2.9 1 1 2 3 3 3 0 Putative coat protein CENP-Q PF13094.1 ETO09877.1 - 0.72 9.8 9.5 0.22 11.5 0.9 2.7 1 1 2 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit SlyX PF04102.7 ETO09877.1 - 0.74 10.2 4.3 0.82 10.0 1.2 2.4 1 1 1 2 2 2 0 SlyX V_ATPase_I PF01496.14 ETO09877.1 - 0.92 7.2 4.4 1.1 6.9 3.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.5 ETO09877.1 - 1.2 9.2 6.7 0.51 10.4 2.5 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.7 ETO09877.1 - 2.6 7.8 6.1 4.3 7.1 3.2 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Vert_HS_TF PF06546.6 ETO09877.1 - 2.6 7.3 6.4 4.9 6.4 4.4 1.5 1 1 0 1 1 1 0 Vertebrate heat shock transcription factor IPP-2 PF04979.9 ETO09880.1 - 1.1 9.4 6.1 0.57 10.4 0.2 2.7 3 0 0 3 3 3 0 Protein phosphatase inhibitor 2 (IPP-2) Prion PF00377.13 ETO09880.1 - 1.8 8.2 8.6 1.2 8.8 0.2 3.0 2 1 1 3 3 3 0 Prion/Doppel alpha-helical domain BAF PF02961.9 ETO09881.1 - 0.0084 16.3 0.5 0.17 12.2 0.2 2.2 2 0 0 2 2 2 1 Barrier to autointegration factor Ku_N PF03731.10 ETO09881.1 - 0.028 13.8 0.1 0.049 13.0 0.1 1.3 1 0 0 1 1 1 0 Ku70/Ku80 N-terminal alpha/beta domain Ank_2 PF12796.2 ETO09882.1 - 4.1e-18 65.4 0.1 1.7e-15 57.0 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETO09882.1 - 1.1e-16 59.6 0.2 1.1e-09 37.5 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 ETO09882.1 - 1.4e-11 43.4 0.1 1.4e-05 24.8 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 ETO09882.1 - 2.8e-11 43.6 0.0 2.2e-05 24.8 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO09882.1 - 5.3e-10 39.2 0.0 5.9e-08 32.7 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) STT3 PF02516.9 ETO09882.1 - 0.0099 14.8 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit AAA_10 PF12846.2 ETO09882.1 - 0.076 12.4 0.0 0.099 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain UME PF08064.8 ETO09882.1 - 0.095 12.6 2.6 0.11 12.4 0.4 2.1 2 0 0 2 2 2 0 UME (NUC010) domain U1snRNP70_N PF12220.3 ETO09882.1 - 5.8 7.3 9.2 3.7 7.9 0.3 2.8 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF2179 PF10035.4 ETO09883.1 - 0.026 14.1 0.1 0.056 13.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2179) DcpS_C PF11969.3 ETO09884.1 - 6.6e-16 58.5 1.2 1e-13 51.5 0.9 2.7 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 ETO09884.1 - 9.6e-13 48.5 0.9 3.4e-12 46.7 0.3 2.1 2 0 0 2 2 2 1 HIT domain Chordopox_A35R PF05989.7 ETO09884.1 - 0.014 15.0 0.1 0.032 13.8 0.1 1.5 1 0 0 1 1 1 0 Chordopoxvirus A35R protein Hom_end_hint PF05203.11 ETO09884.1 - 0.041 13.6 0.0 0.047 13.4 0.0 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint Pox_F11 PF04943.7 ETO09885.1 - 0.093 11.5 6.4 0.1 11.4 4.5 1.0 1 0 0 1 1 1 0 Poxvirus F11 protein TolB_N PF04052.8 ETO09885.1 - 0.14 12.2 1.2 0.25 11.4 0.3 1.8 1 1 1 2 2 2 0 TolB amino-terminal domain DUF1672 PF07901.6 ETO09885.1 - 0.22 10.5 6.6 0.28 10.1 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) AAA_32 PF13654.1 ETO09885.1 - 0.27 9.8 6.3 0.31 9.6 4.4 1.2 1 0 0 1 1 1 0 AAA domain DUF724 PF05266.9 ETO09885.1 - 0.3 10.6 5.9 0.37 10.4 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF2258 PF10015.4 ETO09885.1 - 0.61 9.9 2.7 1.4 8.8 1.9 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2258) AAA_23 PF13476.1 ETO09885.1 - 2.7 8.2 13.8 2.9 8.1 9.6 1.2 1 0 0 1 1 1 0 AAA domain DUF1660 PF07874.6 ETO09886.1 - 0.044 14.0 0.6 0.29 11.4 0.1 2.5 3 0 0 3 3 3 0 Prophage protein (DUF1660) DUF2004 PF09406.5 ETO09886.1 - 0.67 10.0 3.9 0.76 9.8 1.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2004) HEAT PF02985.17 ETO09888.1 - 0.0055 16.6 0.0 0.038 14.0 0.0 2.3 2 0 0 2 2 2 1 HEAT repeat Cnd1 PF12717.2 ETO09888.1 - 0.017 15.0 1.9 1.5 8.6 0.3 2.1 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF3137 PF11335.3 ETO09888.1 - 0.043 13.4 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3137) XhlA PF10779.4 ETO09890.1 - 0.1 12.5 0.8 0.18 11.7 0.5 1.5 1 1 0 1 1 1 0 Haemolysin XhlA Med2 PF11214.3 ETO09891.1 - 0.19 11.7 2.0 0.25 11.3 0.3 1.9 1 1 1 2 2 2 0 Mediator complex subunit 2 WD40 PF00400.27 ETO09892.1 - 1.4e-62 205.4 7.2 3.3e-10 39.4 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Kelch_5 PF13854.1 ETO09892.1 - 5.1e-09 35.9 4.4 0.0031 17.4 0.6 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 ETO09892.1 - 6.4e-09 35.6 9.0 0.0001 22.2 0.4 5.1 4 1 1 5 5 4 2 Kelch motif Kelch_1 PF01344.20 ETO09892.1 - 5.6e-07 29.0 10.2 0.0016 17.9 1.0 5.0 6 0 0 6 6 6 2 Kelch motif Cytochrom_D1 PF02239.11 ETO09892.1 - 3.7e-05 22.1 0.3 0.00036 18.9 0.0 2.5 3 0 0 3 3 3 1 Cytochrome D1 heme domain Kelch_3 PF13415.1 ETO09892.1 - 0.00031 20.7 0.3 0.012 15.8 0.0 3.4 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO09892.1 - 0.00037 20.2 1.4 0.3 10.9 0.1 4.8 5 0 0 5 5 5 1 Galactose oxidase, central domain Methyltransf_3 PF01596.12 ETO09892.1 - 0.002 17.1 0.0 0.13 11.3 0.0 2.6 2 1 1 3 3 3 1 O-methyltransferase Kelch_2 PF07646.10 ETO09892.1 - 0.0026 17.4 3.7 0.17 11.6 0.4 3.9 3 0 0 3 3 3 1 Kelch motif SGL PF08450.7 ETO09892.1 - 0.0056 16.0 0.1 0.032 13.6 0.0 2.3 2 1 1 3 3 3 1 SMP-30/Gluconolaconase/LRE-like region PD40 PF07676.7 ETO09892.1 - 0.033 13.8 7.9 18 5.1 0.0 6.3 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 ETO09892.1 - 2 7.7 6.7 47 3.4 0.0 5.0 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature MFS_1 PF07690.11 ETO09893.1 - 0.00036 19.3 17.0 0.00036 19.3 11.8 2.8 2 1 1 3 3 3 3 Major Facilitator Superfamily tRNA_NucTran2_2 PF13735.1 ETO09894.1 - 1.2 8.9 10.2 0.31 10.8 1.1 3.6 3 1 0 3 3 3 0 tRNA nucleotidyltransferase domain 2 putative Zip PF02535.17 ETO09895.1 - 4e-38 131.1 20.2 2.9e-25 88.9 6.3 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter WD40 PF00400.27 ETO09896.1 - 9.1e-25 85.5 4.2 1.6e-07 30.8 0.0 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO09896.1 - 0.0011 17.2 0.3 0.83 7.7 0.0 2.7 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Kunitz_legume PF00197.13 ETO09896.1 - 0.015 14.8 0.4 0.024 14.1 0.2 1.2 1 0 0 1 1 1 0 Trypsin and protease inhibitor Kelch_1 PF01344.20 ETO09897.1 - 1.9e-08 33.6 0.8 3.3e-05 23.3 0.2 3.8 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETO09897.1 - 9.7e-08 31.6 0.1 0.033 13.9 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO09897.1 - 1.1e-06 28.5 2.4 0.0056 16.8 0.1 3.7 2 1 1 3 3 3 2 Kelch motif Kelch_3 PF13415.1 ETO09897.1 - 1.2e-06 28.4 0.0 4.8e-05 23.4 0.0 3.1 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO09897.1 - 0.00011 21.7 4.3 0.009 15.7 0.3 4.2 4 0 0 4 4 4 1 Kelch motif DUF2272 PF10030.4 ETO09897.1 - 0.022 14.2 0.0 0.19 11.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2272) RE_MjaI PF09568.5 ETO09898.1 - 0.042 13.3 0.3 0.042 13.3 0.2 2.1 3 0 0 3 3 3 0 MjaI restriction endonuclease DUF2456 PF10445.4 ETO09898.1 - 0.091 12.6 1.0 0.23 11.3 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2456) NUMOD1 PF07453.8 ETO09899.1 - 0.021 14.6 0.5 0.056 13.3 0.0 2.0 2 0 0 2 2 2 0 NUMOD1 domain Proteasome PF00227.21 ETO09902.1 - 2.8e-34 118.0 0.2 3e-27 95.1 0.0 3.1 1 1 1 2 2 2 2 Proteasome subunit UPF0542 PF15086.1 ETO09903.1 - 0.075 12.7 0.1 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 ORC5_C PF14630.1 ETO09903.1 - 0.17 11.3 3.3 0.61 9.4 0.1 2.1 1 1 0 2 2 2 0 Origin recognition complex (ORC) subunit 5 C-terminus DUF2098 PF09871.4 ETO09903.1 - 1.6 8.7 6.0 0.44 10.5 1.4 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) HAD PF12710.2 ETO09904.1 - 2.3e-07 31.1 0.1 3.9e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1981 PF09324.5 ETO09904.1 - 0.03 13.8 1.1 0.078 12.5 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) TIP120 PF08623.5 ETO09904.1 - 0.041 13.4 0.4 0.087 12.4 0.3 1.6 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) Ribonuc_red_2_N PF08471.5 ETO09904.1 - 0.058 13.4 0.9 0.12 12.4 0.6 1.4 1 0 0 1 1 1 0 Class II vitamin B12-dependent ribonucleotide reductase Z1 PF10593.4 ETO09904.1 - 0.69 9.0 5.1 1.7 7.8 3.1 1.9 1 1 1 2 2 2 0 Z1 domain RPEL PF02755.10 ETO09905.1 - 1.2e-06 27.6 2.8 0.082 12.2 0.0 4.2 3 1 0 3 3 3 3 RPEL repeat DUF2457 PF10446.4 ETO09905.1 - 0.0046 15.7 23.0 0.0074 15.0 13.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) Sporozoite_P67 PF05642.6 ETO09905.1 - 0.55 8.0 13.1 0.019 12.8 3.6 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen CENP-B_dimeris PF09026.5 ETO09905.1 - 9.5 6.5 25.5 41 4.5 17.7 2.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FYVE PF01363.16 ETO09906.1 - 1e-08 34.9 14.6 2.1e-08 33.9 10.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 ETO09906.1 - 9.8e-05 22.2 10.1 0.00013 21.8 5.6 2.1 2 0 0 2 2 2 1 FYVE-type zinc finger zf-C3HC4_2 PF13923.1 ETO09906.1 - 8.4 6.5 12.3 24 5.0 8.5 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CLASP_N PF12348.3 ETO09907.1 - 2.5e-13 49.9 0.8 3.4e-13 49.5 0.6 1.2 1 0 0 1 1 1 1 CLASP N terminal ABC_tran_2 PF12848.2 ETO09908.1 - 0.068 13.0 1.0 0.068 13.0 0.7 2.8 2 1 0 2 2 2 0 ABC transporter DUF4636 PF15468.1 ETO09908.1 - 0.25 10.7 9.7 0.37 10.2 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) BPL_N PF09825.4 ETO09908.1 - 0.37 9.5 7.7 0.48 9.1 5.3 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal DUF3087 PF11286.3 ETO09908.1 - 1.4 8.1 4.8 0.76 8.9 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) Phage_terminase PF10668.4 ETO09909.1 - 0.069 12.9 0.3 0.16 11.8 0.2 1.5 1 0 0 1 1 1 0 Phage terminase small subunit EXS PF03124.9 ETO09910.1 - 3.5e-32 111.8 13.0 5e-32 111.2 9.0 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.14 ETO09911.1 - 4e-10 39.9 1.9 5.6e-10 39.4 1.3 1.2 1 0 0 1 1 1 1 SPX domain SPX PF03105.14 ETO09912.1 - 2e-07 31.1 17.4 1.2e-06 28.5 12.0 2.2 1 1 0 1 1 1 1 SPX domain RXT2_N PF08595.6 ETO09912.1 - 0.0022 17.7 10.7 0.0033 17.2 7.4 1.2 1 0 0 1 1 1 1 RXT2-like, N-terminal PLRV_ORF5 PF01690.12 ETO09912.1 - 0.0059 15.8 6.4 0.0066 15.6 4.5 1.0 1 0 0 1 1 1 1 Potato leaf roll virus readthrough protein RR_TM4-6 PF06459.7 ETO09912.1 - 0.082 12.7 11.4 0.097 12.5 7.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.17 ETO09912.1 - 0.12 11.3 2.3 0.14 11.1 1.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Cas_CT1975 PF09344.5 ETO09912.1 - 0.26 10.6 7.6 0.31 10.3 5.3 1.1 1 0 0 1 1 1 0 CT1975-like protein PRP1_N PF06424.7 ETO09912.1 - 0.27 11.5 13.2 0.39 11.0 9.2 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal RNA_pol_Rpb1_1 PF04997.7 ETO09912.1 - 0.38 9.9 13.1 0.49 9.6 9.1 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 GAGA_bind PF06217.7 ETO09912.1 - 0.52 10.2 10.9 0.69 9.8 7.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family CotH PF08757.6 ETO09912.1 - 1.5 7.9 9.2 2.5 7.2 6.4 1.2 1 0 0 1 1 1 0 CotH protein Ycf1 PF05758.7 ETO09912.1 - 1.8 6.1 15.5 2.2 5.8 10.8 1.0 1 0 0 1 1 1 0 Ycf1 FRG2 PF15315.1 ETO09912.1 - 3.1 7.7 11.5 4 7.3 8.0 1.1 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 DUF694 PF05107.7 ETO09912.1 - 3.2 6.9 14.2 4.1 6.5 9.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF694) DDHD PF02862.12 ETO09912.1 - 3.6 7.3 9.6 5 6.8 6.7 1.2 1 0 0 1 1 1 0 DDHD domain FAM60A PF15396.1 ETO09912.1 - 3.9 7.1 13.3 5.2 6.7 9.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Neur_chan_memb PF02932.11 ETO09912.1 - 9.6 6.0 6.9 13 5.5 4.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Tubulin PF00091.20 ETO09913.1 - 3e-29 102.4 0.2 5.4e-29 101.5 0.1 1.4 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.4 ETO09913.1 - 0.039 14.0 0.1 0.093 12.7 0.1 1.7 1 1 1 2 2 2 0 Misato Segment II tubulin-like domain CagX PF03524.10 ETO09913.1 - 0.063 12.5 0.2 0.077 12.2 0.1 1.0 1 0 0 1 1 1 0 Conjugal transfer protein Tubulin_C PF03953.12 ETO09914.1 - 6.5e-24 84.3 0.0 1e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 ETO09914.1 - 1.4e-10 41.4 0.0 2.1e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Invas_SpaK PF03519.9 ETO09915.1 - 0.0093 15.7 1.8 0.019 14.7 1.3 1.6 1 0 0 1 1 1 1 Invasion protein B family MotCF PF09158.5 ETO09915.1 - 0.067 12.8 0.8 0.11 12.2 0.5 1.5 1 1 0 1 1 1 0 Bacteriophage T4 MotA, C-terminal TBPIP PF07106.8 ETO09915.1 - 0.56 9.7 5.0 0.4 10.1 2.3 1.5 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Lyase_1 PF00206.15 ETO09916.1 - 1e-100 336.9 0.7 4e-99 331.7 0.5 2.1 1 1 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 ETO09916.1 - 2.6e-21 75.4 2.9 2.2e-16 59.6 0.5 2.5 2 0 0 2 2 2 2 Fumarase C C-terminus Delta_lysin PF05372.6 ETO09916.1 - 0.11 11.8 0.2 0.21 10.9 0.1 1.5 1 0 0 1 1 1 0 Delta lysin family EST1 PF10374.4 ETO09917.1 - 0.02 14.9 1.2 0.028 14.4 0.4 1.6 2 0 0 2 2 2 0 Telomerase activating protein Est1 NIF PF03031.13 ETO09918.1 - 3.2e-15 56.1 1.7 2.5e-06 27.2 0.0 3.7 3 0 0 3 3 3 3 NLI interacting factor-like phosphatase IRS PF02174.12 ETO09919.1 - 0.0058 16.2 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 PTB domain (IRS-1 type) FERM_M PF00373.13 ETO09919.1 - 0.054 13.6 1.9 0.21 11.7 0.2 2.5 2 2 0 2 2 2 0 FERM central domain DLIC PF05783.6 ETO09920.1 - 1.2e-15 57.1 1.1 3.2e-12 45.8 0.0 2.1 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) APC10 PF03256.11 ETO09920.1 - 0.031 13.8 0.1 0.054 13.0 0.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) MDFI PF15316.1 ETO09920.1 - 0.11 12.4 1.4 0.42 10.5 0.2 2.1 2 0 0 2 2 2 0 MyoD family inhibitor WD40 PF00400.27 ETO09922.1 - 1.4e-69 227.6 24.7 1.1e-11 44.1 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO09922.1 - 9.6e-15 53.7 9.9 0.0032 15.6 0.2 6.0 2 2 3 6 6 6 6 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO09922.1 - 0.0019 17.0 6.5 1.8 7.2 0.4 4.7 1 1 1 2 2 2 2 Nup133 N terminal like BBS2_Mid PF14783.1 ETO09922.1 - 0.007 16.1 0.3 5.1 6.9 0.0 4.6 3 2 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Hira PF07569.6 ETO09922.1 - 1 8.5 6.8 13 4.9 0.0 4.4 4 1 2 6 6 6 0 TUP1-like enhancer of split WD40 PF00400.27 ETO09924.1 - 1.5e-195 627.0 69.3 1.1e-12 47.2 0.2 16.6 16 0 0 16 16 16 16 WD domain, G-beta repeat Nup160 PF11715.3 ETO09924.1 - 6.5e-17 60.8 22.0 0.22 9.6 0.1 12.3 1 1 5 8 8 8 8 Nucleoporin Nup120/160 NACHT PF05729.7 ETO09924.1 - 1.2e-08 34.7 0.0 2.9e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.7 ETO09924.1 - 4.8e-06 26.1 30.5 6.3 6.5 0.0 11.9 13 0 0 13 13 13 2 WD40-like Beta Propeller Repeat AAA_18 PF13238.1 ETO09924.1 - 0.00039 20.7 3.4 0.00057 20.1 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETO09924.1 - 0.0029 17.7 0.0 0.011 15.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO09924.1 - 0.0055 17.5 0.0 0.028 15.2 0.0 2.3 1 0 0 1 1 1 1 AAA domain zf-RING_5 PF14634.1 ETO09925.1 - 0.015 15.0 10.3 0.015 15.0 7.2 2.5 2 0 0 2 2 2 0 zinc-RING finger domain SbmA_BacA PF05992.7 ETO09925.1 - 0.056 12.6 0.7 0.087 12.0 0.5 1.2 1 0 0 1 1 1 0 SbmA/BacA-like family WD40 PF00400.27 ETO09926.1 - 2.7e-65 214.0 30.6 1.7e-11 43.5 0.1 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO09926.1 - 8.2e-12 44.0 5.1 0.0087 14.2 0.0 5.2 1 1 3 5 5 5 4 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO09926.1 - 5.5e-05 23.4 7.1 7.4e-05 23.0 3.3 2.7 2 0 0 2 2 2 1 TRAF-type zinc finger DUF3601 PF12208.3 ETO09926.1 - 0.00066 19.5 0.2 0.16 11.9 0.0 3.4 3 1 0 3 3 3 1 Domain of unknown function (DUF3601) PQQ_2 PF13360.1 ETO09926.1 - 0.03 13.7 0.3 17 4.7 0.0 3.4 1 1 2 3 3 3 0 PQQ-like domain Bap31 PF05529.7 ETO09926.1 - 1.4 8.3 6.6 2.4 7.5 4.6 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like WD40 PF00400.27 ETO09928.1 - 1.2e-53 177.1 18.8 3.7e-12 45.6 0.0 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO09928.1 - 1.5e-13 49.7 4.5 6.3e-05 21.3 0.1 5.0 1 1 4 5 5 5 5 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO09928.1 - 0.0038 16.5 1.3 0.02 14.2 0.2 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4221) DUF1900 PF08954.6 ETO09928.1 - 0.011 15.2 0.1 4.7 6.7 0.0 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF1900) Methyltransf_25 PF13649.1 ETO09928.1 - 0.012 15.9 0.0 1.1 9.6 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Imm21 PF15569.1 ETO09928.1 - 0.071 12.8 0.9 0.3 10.8 0.1 2.1 2 0 0 2 2 2 0 Immunity protein 21 KH_1 PF00013.24 ETO09929.1 - 4.5e-32 109.4 7.3 1e-10 41.0 0.0 3.8 3 1 0 3 3 3 3 KH domain KH_3 PF13014.1 ETO09929.1 - 3.6e-15 55.1 5.2 3.1e-05 23.5 0.1 3.8 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 ETO09929.1 - 0.00039 19.9 2.2 0.8 9.3 0.0 3.6 4 0 0 4 4 4 2 KH domain TPR_12 PF13424.1 ETO09930.1 - 1.3e-15 57.0 1.3 1.7e-08 34.2 0.0 1.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO09930.1 - 6.9e-06 25.6 2.0 1.6e-05 24.4 1.4 1.6 1 0 0 1 1 1 1 TPR repeat TPR_8 PF13181.1 ETO09930.1 - 1e-05 24.9 4.7 6.6e-05 22.3 3.3 2.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO09930.1 - 0.00014 21.4 0.1 0.00035 20.1 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO09930.1 - 0.00017 21.2 3.8 0.00047 19.8 2.2 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETO09930.1 - 0.00034 20.4 0.0 0.00077 19.3 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO09930.1 - 0.0058 16.1 6.3 0.008 15.7 3.3 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat ATP-synt_F PF01990.12 ETO09930.1 - 0.022 15.1 5.4 0.033 14.5 0.7 2.4 1 1 1 2 2 2 0 ATP synthase (F/14-kDa) subunit Fis1_TPR_C PF14853.1 ETO09930.1 - 0.045 13.6 2.4 0.12 12.2 1.7 1.6 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat DUF627 PF04781.7 ETO09930.1 - 0.051 13.1 2.3 0.088 12.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF627) AAA PF00004.24 ETO09930.1 - 0.13 12.5 0.9 0.26 11.4 0.6 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Apc3 PF12895.2 ETO09930.1 - 0.88 9.7 8.9 1.5 9.0 2.6 3.5 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 CAF-1_p150 PF11600.3 ETO09931.1 - 0.0023 17.3 63.4 0.0027 17.1 44.0 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal MIP-T3 PF10243.4 ETO09931.1 - 0.092 11.2 65.9 0.11 10.9 45.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CDC27 PF09507.5 ETO09931.1 - 0.26 10.4 52.8 0.32 10.1 36.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SprA-related PF12118.3 ETO09931.1 - 2.7 7.2 32.2 4.3 6.5 22.3 1.3 1 0 0 1 1 1 0 SprA-related family PLRV_ORF5 PF01690.12 ETO09931.1 - 7.6 5.5 27.3 9 5.3 18.9 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Pilt PF15453.1 ETO09931.1 - 8.7 5.9 26.5 9.8 5.7 18.3 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Lipase_3 PF01764.20 ETO09932.1 - 4.4e-31 107.3 0.1 9e-31 106.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 ETO09932.1 - 0.0032 17.3 0.1 0.0042 16.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETO09932.1 - 0.014 15.1 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PE-PPE PF08237.6 ETO09932.1 - 0.016 14.6 0.1 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain DUF2974 PF11187.3 ETO09932.1 - 0.026 13.9 0.0 0.14 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Cutinase PF01083.17 ETO09932.1 - 0.078 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Cutinase Adeno_E3B PF03376.9 ETO09932.1 - 4 7.4 7.0 10 6.1 4.8 1.6 1 0 0 1 1 1 0 Adenovirus E3B protein FKBP_C PF00254.23 ETO09933.1 - 3e-12 46.3 0.0 4.9e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF2890 PF11081.3 ETO09933.1 - 0.044 13.8 1.3 0.066 13.2 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CDC45 PF02724.9 ETO09933.1 - 0.11 10.5 3.8 0.14 10.1 2.6 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 ETO09933.1 - 0.58 9.1 11.5 0.97 8.4 8.0 1.2 1 0 0 1 1 1 0 BUD22 RGS PF00615.14 ETO09934.1 - 0.00014 21.9 3.3 0.00014 21.9 2.3 2.7 3 0 0 3 3 3 1 Regulator of G protein signaling domain HrpB1_HrpK PF09613.5 ETO09935.1 - 0.0052 16.2 1.1 0.013 14.9 0.8 1.7 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB1_HrpK) Baculo_PEP_C PF04513.7 ETO09935.1 - 0.1 12.4 25.7 0.033 14.0 5.7 3.9 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Rootletin PF15035.1 ETO09935.1 - 0.42 10.5 37.8 0.36 10.7 12.3 3.2 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion DUF948 PF06103.6 ETO09935.1 - 0.49 10.2 21.8 0.53 10.1 3.8 4.4 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) COG2 PF06148.6 ETO09935.1 - 1.2 8.9 20.7 0.033 14.0 4.3 3.7 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 CENP-Q PF13094.1 ETO09935.1 - 1.2 9.0 43.9 0.017 15.1 10.8 4.0 1 1 2 4 4 4 0 CENP-Q, a CENPA-CAD centromere complex subunit Prefoldin PF02996.12 ETO09935.1 - 2 8.0 28.9 0.03 13.9 1.5 5.5 3 2 1 4 4 4 0 Prefoldin subunit DUF342 PF03961.8 ETO09935.1 - 3.8 5.7 27.3 0.4 9.0 3.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF342) DUF2312 PF10073.4 ETO09935.1 - 4 6.8 10.7 2.5 7.5 2.8 3.3 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) Hormone_1 PF00103.15 ETO09935.1 - 8 5.7 15.4 2.7 7.2 2.7 3.1 2 2 0 3 3 3 0 Somatotropin hormone family tRNA-synt_His PF13393.1 ETO09935.1 - 8.3 5.3 12.2 0.25 10.3 2.7 2.1 2 0 0 2 2 2 0 Histidyl-tRNA synthetase HXXEE PF13787.1 ETO09936.1 - 0.074 13.4 0.5 0.074 13.4 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif Cation_ATPase_C PF00689.16 ETO09937.1 - 0.0016 17.9 3.4 0.0024 17.4 2.3 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus DUF2569 PF10754.4 ETO09937.1 - 0.014 15.6 4.9 0.082 13.1 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) UPF0104 PF03706.8 ETO09937.1 - 0.016 14.5 0.3 0.019 14.2 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) DUF4131 PF13567.1 ETO09937.1 - 0.048 13.0 0.4 0.067 12.5 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) RDD PF06271.7 ETO09937.1 - 0.14 12.0 2.2 0.26 11.1 1.5 1.3 1 0 0 1 1 1 0 RDD family DUF3481 PF11980.3 ETO09937.1 - 0.27 11.0 1.9 0.31 10.8 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) DUF1980 PF09323.5 ETO09937.1 - 0.5 10.0 7.7 0.13 12.0 2.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) Synaptobrevin PF00957.16 ETO09937.1 - 1.5 8.4 6.9 0.28 10.7 0.3 2.2 2 0 0 2 2 2 0 Synaptobrevin Vpu PF00558.14 ETO09937.1 - 2.3 7.8 6.6 5.1 6.7 0.7 2.3 2 0 0 2 2 2 0 Vpu protein CAML PF14963.1 ETO09937.1 - 2.9 7.1 6.1 4.8 6.4 0.1 2.2 1 1 1 2 2 2 0 Calcium signal-modulating cyclophilin ligand Chordopox_A13L PF05961.6 ETO09937.1 - 3.8 7.5 8.8 4.6 7.2 1.0 2.9 2 1 1 3 3 3 0 Chordopoxvirus A13L protein DUF4446 PF14584.1 ETO09937.1 - 4.8 7.0 6.8 1.6 8.5 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) WBP-1 PF11669.3 ETO09937.1 - 5.1 7.2 5.9 2.5 8.2 1.6 2.1 1 1 1 2 2 2 0 WW domain-binding protein 1 EF-hand_1 PF00036.27 ETO09938.1 - 1.8e-07 29.9 0.2 1e-06 27.5 0.2 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 ETO09938.1 - 2.4e-06 26.9 1.2 1.1e-05 24.9 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 ETO09938.1 - 4.6e-05 22.5 3.2 5.7e-05 22.2 0.2 2.6 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 ETO09938.1 - 0.0002 21.4 0.1 0.0002 21.4 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 ETO09938.1 - 0.26 10.9 0.1 0.26 10.9 0.1 2.5 3 0 0 3 3 3 0 EF-hand domain pair DUF3450 PF11932.3 ETO09938.1 - 0.31 10.2 20.2 0.14 11.4 1.7 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.7 ETO09938.1 - 5.8 6.6 22.8 0.74 9.5 5.6 3.0 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein CMV_1a PF12467.3 ETO09939.1 - 0.14 12.4 6.5 0.19 12.1 4.5 1.2 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Tyr-DNA_phospho PF06087.7 ETO09940.1 - 2.2e-73 247.3 4.0 7.1e-73 245.7 2.2 2.1 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PTE PF02126.13 ETO09940.1 - 0.19 10.6 0.0 0.33 9.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotriesterase family FixO PF02433.10 ETO09941.1 - 0.35 10.2 3.9 0.39 10.0 1.5 1.9 2 0 0 2 2 2 0 Cytochrome C oxidase, mono-heme subunit/FixO zf-C3HC4_2 PF13923.1 ETO09943.1 - 0.0032 17.4 2.8 0.03 14.3 2.0 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Cys_knot PF00007.17 ETO09943.1 - 0.11 12.6 4.8 0.17 12.0 3.3 1.3 1 1 0 1 1 1 0 Cystine-knot domain zf-RING-like PF08746.6 ETO09943.1 - 4.8 7.2 9.6 18 5.3 6.3 2.3 2 1 1 3 3 3 0 RING-like domain Apis_Csd PF11671.3 ETO09944.1 - 0.47 10.2 8.8 0.94 9.2 6.1 1.6 1 0 0 1 1 1 0 Complementary sex determiner protein Exo_endo_phos_2 PF14529.1 ETO09945.1 - 7.3e-21 73.9 2.1 7.3e-21 73.9 1.4 2.4 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 ETO09945.1 - 6.2e-06 26.3 1.5 6.2e-06 26.3 1.1 1.5 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family RabGAP-TBC PF00566.13 ETO09946.1 - 2.3e-25 89.3 0.4 2.6e-25 89.1 0.3 1.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain 2Fe-2S_thioredx PF01257.14 ETO09946.1 - 0.035 13.6 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin TarH PF02203.10 ETO09948.1 - 0.037 13.8 0.7 0.056 13.2 0.5 1.2 1 0 0 1 1 1 0 Tar ligand binding domain homologue DUF2304 PF10066.4 ETO09948.1 - 0.065 13.0 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) HemY_N PF07219.8 ETO09948.1 - 0.16 11.5 0.6 0.27 10.7 0.4 1.3 1 0 0 1 1 1 0 HemY protein N-terminus EamA PF00892.15 ETO09949.1 - 0.021 14.8 4.8 0.034 14.2 3.4 1.3 1 0 0 1 1 1 0 EamA-like transporter family ATP-synt_8 PF00895.15 ETO09949.1 - 4.9 7.4 6.4 26 5.1 0.1 3.1 2 1 0 2 2 2 0 ATP synthase protein 8 WD40 PF00400.27 ETO09950.1 - 1.6e-33 113.3 6.0 1.1e-10 40.9 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF1258 PF06869.7 ETO09950.1 - 0.0002 20.5 0.6 0.0097 15.0 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1258) eIF2A PF08662.6 ETO09950.1 - 0.00044 20.0 0.1 0.011 15.5 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO09950.1 - 0.002 16.3 1.0 1.6 6.7 0.1 2.8 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO09950.1 - 0.012 14.3 0.0 1.1 7.9 0.0 2.0 1 1 1 2 2 2 0 Nup133 N terminal like CppA_C PF14507.1 ETO09950.1 - 0.054 13.6 0.1 2.3 8.4 0.0 2.4 2 0 0 2 2 2 0 CppA C-terminal Surfac_D-trimer PF09006.6 ETO09950.1 - 0.15 11.8 0.2 0.65 9.7 0.0 2.1 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation WD40 PF00400.27 ETO09951.1 - 2e-19 68.6 0.1 6.4e-11 41.7 0.0 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO09951.1 - 0.0011 17.2 0.1 0.41 8.7 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Gp49 PF05973.9 ETO09951.1 - 0.032 14.2 0.5 0.054 13.5 0.4 1.4 1 0 0 1 1 1 0 Phage derived protein Gp49-like (DUF891) Cytochrom_D1 PF02239.11 ETO09951.1 - 0.056 11.7 0.0 0.092 11.0 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain PD40 PF07676.7 ETO09951.1 - 0.084 12.5 0.4 1.3 8.7 0.0 2.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat OTCace_N PF02729.16 ETO09954.1 - 4.1e-47 159.4 0.0 6.4e-47 158.7 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 ETO09954.1 - 5e-40 136.9 0.0 7.4e-40 136.3 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Toxin_6 PF05453.7 ETO09954.1 - 0.91 9.8 3.9 5.9 7.2 0.2 2.6 2 0 0 2 2 2 0 BmTXKS1/BmP02 toxin family DUF1777 PF08648.7 ETO09955.1 - 0.0063 16.2 47.1 0.0063 16.2 32.6 3.3 2 1 1 3 3 3 1 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 ETO09955.1 - 4 5.7 131.2 4 5.8 21.2 2.3 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Sec16_C PF12931.2 ETO09956.1 - 2.4e-06 27.5 0.2 3e-06 27.2 0.2 1.1 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 MTS PF05175.9 ETO09956.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase small domain Pkinase PF00069.20 ETO09958.1 - 6.9e-12 45.0 0.0 1.8e-11 43.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Mit_ribos_Mrp51 PF11709.3 ETO09958.1 - 0.23 10.6 3.2 3.3 6.8 2.2 2.0 1 1 0 1 1 1 0 Mitochondrial ribosomal protein subunit Pkinase PF00069.20 ETO09959.1 - 1.6e-09 37.3 4.8 2.8e-09 36.5 1.9 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO09959.1 - 3.4e-05 23.0 5.2 0.016 14.2 0.1 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase DUF2951 PF11166.3 ETO09959.1 - 0.034 13.9 0.6 0.092 12.6 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) RF-1 PF00472.15 ETO09959.1 - 0.038 13.8 0.3 0.074 12.8 0.2 1.4 1 0 0 1 1 1 0 RF-1 domain ATP-synt_8 PF00895.15 ETO09959.1 - 0.91 9.7 2.7 1.4 9.1 0.2 2.3 2 0 0 2 2 2 0 ATP synthase protein 8 DAP_epimerase PF01678.14 ETO09960.1 - 4e-27 94.5 0.0 5.9e-12 45.5 0.0 3.2 3 0 0 3 3 3 3 Diaminopimelate epimerase DUF2195 PF09961.4 ETO09960.1 - 0.1 12.4 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2195) WD40 PF00400.27 ETO09961.1 - 9.8e-45 148.8 21.0 6.9e-11 41.5 0.2 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO09961.1 - 0.00039 18.6 1.7 0.28 9.2 0.1 3.4 1 1 2 3 3 3 3 Nucleoporin Nup120/160 WD40 PF00400.27 ETO09962.1 - 4.2e-49 162.7 21.7 6.1e-12 44.9 0.1 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO09962.1 - 3.6e-08 31.9 7.1 0.00043 18.5 0.3 4.7 1 1 2 4 4 4 4 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO09962.1 - 0.046 13.0 4.9 0.12 11.7 0.5 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4221) PQQ_3 PF13570.1 ETO09962.1 - 0.1 12.9 0.3 58 4.1 0.0 3.4 3 0 0 3 3 3 0 PQQ-like domain DUF4361 PF14274.1 ETO09963.1 - 0.025 14.2 1.2 0.032 13.8 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4361) DUF2263 PF10021.4 ETO09963.1 - 0.17 11.8 1.5 0.22 11.4 1.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2263) GDC-P PF02347.11 ETO09963.1 - 0.18 10.4 1.7 0.2 10.2 1.2 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein PRD PF00874.15 ETO09963.1 - 4.8 7.3 9.8 3.6 7.7 3.6 2.1 1 1 1 2 2 2 0 PRD domain U-box PF04564.10 ETO09964.1 - 6.6e-13 48.4 0.0 2.3e-12 46.6 0.0 2.0 1 0 0 1 1 1 1 U-box domain ERAP1_C PF11838.3 ETO09964.1 - 0.0072 15.6 0.3 0.011 15.0 0.2 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Stathmin PF00836.14 ETO09964.1 - 4.9 6.7 7.7 3.4 7.2 2.1 2.4 1 1 1 2 2 2 0 Stathmin family FliJ PF02050.11 ETO09964.1 - 5.1 7.1 9.8 12 5.9 0.7 2.7 2 1 1 3 3 3 0 Flagellar FliJ protein WD40 PF00400.27 ETO09965.1 - 5.4e-23 79.9 9.6 8.5e-07 28.6 0.0 5.7 6 1 0 6 6 6 4 WD domain, G-beta repeat WD40 PF00400.27 ETO09966.1 - 9.1e-33 110.9 7.3 1.6e-10 40.4 0.0 4.4 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO09966.1 - 3.7e-06 25.3 0.1 0.53 8.3 0.0 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 IRF PF00605.12 ETO09967.1 - 0.03 14.0 4.4 0.049 13.4 2.4 1.7 2 0 0 2 2 2 0 Interferon regulatory factor transcription factor FKBP_N PF01346.13 ETO09967.1 - 1.4 9.0 6.9 2.5 8.1 4.8 1.4 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Peptidase_S49_N PF08496.5 ETO09967.1 - 2.7 7.7 6.9 5.6 6.7 4.8 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PH PF00169.24 ETO09968.1 - 0.14 12.4 2.7 0.2 11.8 1.9 1.2 1 0 0 1 1 1 0 PH domain HHH_2 PF12826.2 ETO09969.1 - 0.4 10.5 1.5 19 5.2 0.1 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif zf-TRAF PF02176.13 ETO09971.1 - 4.3e-06 27.0 6.4 4.3e-06 27.0 4.5 2.7 1 1 2 3 3 3 1 TRAF-type zinc finger WD40 PF00400.27 ETO09972.1 - 4.9e-35 118.1 11.4 2.5e-09 36.6 0.5 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO09972.1 - 1.3e-06 26.8 1.5 0.0012 17.0 0.1 3.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Pox_polyA_pol_C PF12629.2 ETO09972.1 - 0.44 10.2 4.1 1 9.0 2.7 1.7 1 1 1 2 2 2 0 Poxvirus poly(A) polymerase C-terminal domain Euplotes_phero PF05842.6 ETO09972.1 - 1.4 9.2 8.5 0.05 13.9 1.4 2.0 2 0 0 2 2 2 0 Euplotes octocarinatus mating pheromone protein C2 PF00168.25 ETO09973.1 - 1.1e-12 47.6 0.2 2.2e-12 46.6 0.2 1.5 1 0 0 1 1 1 1 C2 domain WD40 PF00400.27 ETO09974.1 - 4.5e-34 115.1 9.9 3e-11 42.7 0.1 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO09974.1 - 3.2e-07 28.8 2.5 0.014 13.5 0.0 3.8 1 1 1 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO09974.1 - 9.5e-06 25.2 0.0 4.4e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO09974.1 - 0.028 12.7 0.2 0.54 8.4 0.0 2.1 1 1 2 3 3 3 0 Cytochrome D1 heme domain Me-amine-dh_H PF06433.6 ETO09974.1 - 0.044 12.4 0.1 1.5 7.4 0.0 2.7 1 1 1 3 3 3 0 Methylamine dehydrogenase heavy chain (MADH) GTP_EFTU_D4 PF14578.1 ETO09974.1 - 0.067 12.8 0.1 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu domain 4 Mid2 PF04478.7 ETO09974.1 - 0.13 11.6 2.9 0.25 10.7 0.2 2.7 2 2 2 4 4 4 0 Mid2 like cell wall stress sensor ECH PF00378.15 ETO09976.1 - 6.6e-09 35.2 0.0 8.1e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF1600 PF07667.6 ETO09976.1 - 0.011 15.8 0.5 0.015 15.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1600) WD40 PF00400.27 ETO09977.1 - 7.7e-17 60.4 0.8 2.4e-11 43.0 0.1 2.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO09977.1 - 0.033 12.3 0.0 0.077 11.1 0.0 1.6 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO09977.1 - 0.061 12.0 0.8 0.11 11.1 0.5 1.4 1 1 0 1 1 1 0 Nup133 N terminal like Claudin_2 PF13903.1 ETO09979.1 - 0.014 15.1 0.2 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF1510 PF07423.6 ETO09979.1 - 0.056 12.8 0.5 0.073 12.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) EphA2_TM PF14575.1 ETO09979.1 - 0.12 12.7 0.0 0.12 12.7 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TRAP_alpha PF03896.11 ETO09979.1 - 0.3 10.0 2.7 0.32 9.9 1.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nucleoplasmin PF03066.10 ETO09979.1 - 0.35 10.3 4.5 0.42 10.1 3.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF3357 PF11837.3 ETO09979.1 - 0.41 10.5 1.8 0.94 9.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) NOA36 PF06524.7 ETO09979.1 - 0.46 9.6 4.2 0.64 9.2 2.9 1.4 1 0 0 1 1 1 0 NOA36 protein IclR PF01614.13 ETO09979.1 - 5 6.8 6.1 0.18 11.4 0.2 1.6 2 0 0 2 2 2 0 Bacterial transcriptional regulator Synapsin_C PF02750.9 ETO09980.1 - 1.4e-21 76.5 1.1 8e-16 57.7 0.0 2.6 2 1 0 2 2 2 2 Synapsin, ATP binding domain Sulfate_transp PF00916.15 ETO09980.1 - 0.026 13.5 0.7 0.042 12.8 0.5 1.2 1 0 0 1 1 1 0 Sulfate transporter family Allexi_40kDa PF05549.6 ETO09981.1 - 0.014 14.6 0.1 0.017 14.4 0.1 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Med30 PF11315.3 ETO09981.1 - 0.1 12.7 0.4 0.27 11.3 0.1 1.7 1 1 1 2 2 2 0 Mediator complex subunit 30 IDO PF01231.13 ETO09981.1 - 0.12 10.7 0.0 0.17 10.3 0.0 1.1 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase DUF4635 PF15466.1 ETO09981.1 - 0.13 11.5 0.4 0.19 10.9 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) DASH_Dad3 PF08656.5 ETO09981.1 - 0.16 11.7 0.7 0.3 10.8 0.5 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad3 Syntaxin PF00804.20 ETO09981.1 - 0.21 11.7 2.1 0.23 11.6 0.6 1.6 1 1 1 2 2 2 0 Syntaxin RVT_1 PF00078.22 ETO09982.1 - 2.4e-05 23.7 0.3 8e-05 22.0 0.0 1.8 1 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF327 PF03885.8 ETO09982.1 - 0.021 14.6 0.3 0.029 14.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF327) DUF615 PF04751.9 ETO09982.1 - 0.067 12.8 0.9 0.12 12.0 0.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF615) FUSC-like PF12805.2 ETO09982.1 - 0.073 11.9 1.0 0.53 9.1 0.1 1.9 1 1 1 2 2 2 0 FUSC-like inner membrane protein yccS Baculo_PEP_C PF04513.7 ETO09982.1 - 0.078 12.8 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PilJ PF13675.1 ETO09982.1 - 0.087 13.1 0.5 0.27 11.5 0.2 1.8 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term XhlA PF10779.4 ETO09982.1 - 3.9 7.4 6.0 14 5.6 3.1 2.3 1 1 1 2 2 2 0 Haemolysin XhlA GatB_Yqey PF02637.13 ETO09983.1 - 0.31 10.7 6.7 0.07 12.8 1.4 1.9 2 0 0 2 2 2 0 GatB domain Thymidylate_kin PF02223.12 ETO09983.1 - 0.54 9.6 5.2 4.5 6.5 0.3 2.1 2 0 0 2 2 2 0 Thymidylate kinase RNA_pol_A_bac PF01000.21 ETO09983.1 - 0.79 9.8 3.9 0.9 9.7 2.5 1.3 1 1 0 1 1 1 0 RNA polymerase Rpb3/RpoA insert domain DUF4473 PF14747.1 ETO09983.1 - 1 9.5 7.5 0.51 10.5 0.8 2.7 1 1 1 3 3 3 0 Domain of unknown function (DUF4473) RPA_interact_M PF14767.1 ETO09983.1 - 3.1 8.6 7.6 13 6.6 5.3 2.0 1 1 0 1 1 1 0 Replication protein A interacting middle Tap-RNA_bind PF09162.5 ETO09984.1 - 0.06 12.9 0.1 0.091 12.3 0.1 1.3 1 0 0 1 1 1 0 Tap, RNA-binding GRP PF07172.6 ETO09985.1 - 0.0083 16.5 13.4 0.0083 16.5 9.3 2.4 2 1 0 2 2 2 1 Glycine rich protein family FYDLN_acid PF09538.5 ETO09985.1 - 1.3 9.6 20.2 0.17 12.4 6.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) RRM_1 PF00076.17 ETO09986.1 - 5.2e-18 64.4 0.1 8.6e-18 63.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO09986.1 - 8.2e-15 54.5 0.0 1.4e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO09986.1 - 4.6e-10 39.2 0.1 8.3e-10 38.3 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spore_III_AF PF09581.5 ETO09986.1 - 0.74 9.6 5.6 1.2 8.9 3.9 1.4 1 1 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) PIH1 PF08190.7 ETO09987.1 - 2.4e-07 30.5 2.5 3e-07 30.2 1.7 1.1 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 PEPCK PF00821.13 ETO09988.1 - 5.5e-37 127.2 0.0 7.2e-37 126.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase Ndr PF03096.9 ETO09988.1 - 0.16 10.4 2.6 0.24 9.8 1.8 1.3 1 0 0 1 1 1 0 Ndr family PEPCK PF00821.13 ETO09989.1 - 2.7e-206 686.2 0.2 3.1e-206 686.0 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase Kelch_1 PF01344.20 ETO09990.1 - 0.00081 18.8 0.3 0.084 12.4 0.1 2.6 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETO09990.1 - 0.0012 18.9 0.2 0.23 11.6 0.0 2.7 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO09990.1 - 0.0032 17.5 0.0 9.1 6.5 0.0 3.3 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO09990.1 - 0.014 15.2 0.3 0.22 11.5 0.0 2.6 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.10 ETO09990.1 - 0.016 14.9 1.3 3.9 7.3 0.0 3.2 3 1 0 3 3 3 0 Kelch motif Cullin_binding PF03556.10 ETO09990.1 - 0.019 15.0 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 Cullin binding LIM PF00412.17 ETO09991.1 - 2.6e-13 49.8 25.5 4.4e-08 33.0 4.7 3.3 3 1 0 3 3 3 2 LIM domain Vps39_2 PF10367.4 ETO09991.1 - 0.23 11.6 14.4 0.54 10.4 0.2 3.7 2 1 2 4 4 4 0 Vacuolar sorting protein 39 domain 2 zf-C2H2_7 PF15269.1 ETO09991.1 - 0.75 9.7 6.3 4.8 7.1 0.5 2.7 2 0 0 2 2 2 0 Zinc-finger zf-FCS PF06467.9 ETO09991.1 - 4.3 7.0 21.9 0.084 12.5 3.4 4.3 4 0 0 4 4 4 0 MYM-type Zinc finger with FCS sequence motif Crystall_3 PF08964.5 ETO09992.1 - 0.057 13.1 0.4 0.057 13.1 0.3 2.5 2 1 1 3 3 3 0 Beta/Gamma crystallin Aldo_ket_red PF00248.16 ETO09993.1 - 5.8e-16 58.1 0.0 8.4e-16 57.6 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family FMO-like PF00743.14 ETO09994.1 - 3.3e-07 28.8 0.0 4.1e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like DUF16 PF01519.11 ETO09995.1 - 0.013 15.7 1.6 0.017 15.3 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 IncA PF04156.9 ETO09995.1 - 0.016 14.7 1.8 0.016 14.8 1.3 1.1 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 ETO09995.1 - 0.033 14.0 5.8 0.078 12.7 4.0 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding MitMem_reg PF13012.1 ETO09995.1 - 0.082 12.9 1.9 0.13 12.3 1.3 1.5 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function NYD-SP28_assoc PF14775.1 ETO09995.1 - 0.083 12.5 1.9 3 7.5 0.1 2.6 1 1 1 2 2 2 0 Sperm tail C-terminal domain Seryl_tRNA_N PF02403.17 ETO09995.1 - 0.16 12.0 3.9 0.25 11.3 2.7 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 ETO09995.1 - 0.22 11.0 4.5 0.86 9.1 3.1 2.0 1 1 0 1 1 1 0 Septum formation initiator MIT PF04212.13 ETO09997.1 - 0.013 15.4 4.4 0.013 15.4 3.0 2.8 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain DUF2877 PF11392.3 ETO09997.1 - 1.1 9.4 4.5 0.72 10.0 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2877) Membralin PF09746.4 ETO09998.1 - 0.026 13.5 0.0 0.048 12.6 0.0 1.4 1 0 0 1 1 1 0 Tumour-associated protein EF-hand_8 PF13833.1 ETO09998.1 - 0.08 12.5 2.1 12 5.6 0.1 3.8 3 1 1 4 4 4 0 EF-hand domain pair Vpu PF00558.14 ETO09998.1 - 0.36 10.4 1.8 0.48 10.0 0.2 2.0 2 0 0 2 2 2 0 Vpu protein Mucin PF01456.12 ETO09999.1 - 0.093 12.4 18.6 0.12 12.1 12.9 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.7 ETO09999.1 - 0.23 9.1 9.6 0.28 8.9 6.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AJAP1_PANP_C PF15298.1 ETO09999.1 - 0.9 9.3 12.0 1.2 8.9 8.3 1.1 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Paramyxo_C PF01692.13 ETO09999.1 - 0.95 9.0 5.6 1.2 8.6 3.9 1.1 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c Peptidase_S64 PF08192.6 ETO09999.1 - 2.5 6.3 9.9 2.6 6.2 6.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 Pap_E4 PF02711.9 ETO09999.1 - 4.1 8.2 6.9 0.97 10.2 2.8 1.6 2 0 0 2 2 2 0 E4 protein WD40 PF00400.27 ETO10000.1 - 4.3e-10 39.0 6.8 8.9e-08 31.7 0.2 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Daxx PF03344.10 ETO10000.1 - 1.2 7.5 60.2 0.043 12.2 28.3 2.5 2 0 0 2 2 2 0 Daxx Family GerA PF03323.8 ETO10000.1 - 4.7 5.2 5.1 0.54 8.3 0.4 1.7 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein Apis_Csd PF11671.3 ETO10001.1 - 0.75 9.5 10.9 0.03 14.1 3.3 1.8 2 0 0 2 2 2 0 Complementary sex determiner protein Parvo_coat PF00740.13 ETO10001.1 - 0.77 8.6 13.6 0.91 8.4 9.4 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 CDC27 PF09507.5 ETO10001.1 - 2.5 7.2 34.2 2.8 7.0 23.7 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SNF2_N PF00176.18 ETO10002.1 - 1.3e-18 66.8 0.1 2.3e-18 66.0 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 ETO10002.1 - 3.5e-10 39.4 0.0 3.8e-07 29.6 0.0 2.4 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain SR-25 PF10500.4 ETO10002.1 - 4.1 6.8 5.9 6.8 6.0 4.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SNF2_N PF00176.18 ETO10003.1 - 2.8e-45 154.4 2.7 2.8e-45 154.4 1.8 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETO10003.1 - 1.5e-15 56.7 0.0 6.2e-15 54.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 ETO10003.1 - 1.1e-13 50.7 0.0 2.6e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 ETO10003.1 - 0.025 14.4 1.0 0.15 11.9 0.0 2.7 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit NACHT PF05729.7 ETO10005.1 - 1.7e-12 47.2 0.0 3.1e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO10005.1 - 9e-06 26.0 3.8 9.2e-06 25.9 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 ETO10005.1 - 3.8e-05 23.8 0.5 0.0001 22.4 0.2 1.8 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 ETO10005.1 - 0.003 18.3 0.5 0.011 16.6 0.0 2.0 1 1 1 2 2 2 1 AAA domain UPF0079 PF02367.12 ETO10005.1 - 0.013 15.1 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 ETO10005.1 - 0.02 14.0 0.2 0.028 13.5 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 ETO10005.1 - 0.021 14.8 0.1 0.17 11.8 0.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 ETO10005.1 - 0.031 13.7 0.0 0.068 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 ETO10005.1 - 0.047 13.9 2.2 0.051 13.8 0.8 1.7 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 ETO10005.1 - 0.08 12.8 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 ETO10005.1 - 0.11 12.6 0.2 0.11 12.6 0.1 2.9 3 1 0 3 3 3 0 RNA helicase AAA_25 PF13481.1 ETO10005.1 - 0.14 11.5 0.0 4.7 6.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain EF-hand_1 PF00036.27 ETO10005.1 - 0.64 9.4 4.3 0.64 9.4 1.4 2.3 2 0 0 2 2 2 0 EF hand s48_45 PF07422.8 ETO10005.1 - 1.4 9.0 12.4 0.44 10.6 0.4 2.5 1 1 1 2 2 2 0 Sexual stage antigen s48/45 domain AAA_21 PF13304.1 ETO10005.1 - 4.2 7.2 16.4 1.8 8.4 7.0 2.4 1 1 0 2 2 2 0 AAA domain RNase_H PF00075.19 ETO10006.1 - 1.8e-18 67.1 0.1 1.8e-18 67.1 0.1 1.5 2 0 0 2 2 2 1 RNase H DUF2971 PF11185.3 ETO10007.1 - 0.033 14.8 0.0 0.16 12.7 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2971) Nro1 PF12753.2 ETO10008.1 - 0.16 10.9 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 DUF3552 PF12072.3 ETO10010.1 - 0.0025 17.0 9.0 0.0025 17.0 6.2 4.3 4 1 0 4 4 4 3 Domain of unknown function (DUF3552) DUF4200 PF13863.1 ETO10010.1 - 4.6 7.1 41.0 1.3 8.9 5.1 4.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4200) DUF4187 PF13821.1 ETO10010.1 - 5.1 6.7 5.5 1.2 8.7 0.2 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF4187) CENP-Q PF13094.1 ETO10010.1 - 5.5 7.0 33.3 0.094 12.7 5.2 4.2 4 0 0 4 4 4 0 CENP-Q, a CENPA-CAD centromere complex subunit PRK PF00485.13 ETO10011.1 - 4.1e-08 33.0 0.3 5.7e-07 29.2 0.2 2.2 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 ETO10011.1 - 5e-06 27.3 1.4 3.2e-05 24.7 1.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETO10011.1 - 0.00038 20.7 0.7 0.0021 18.3 0.5 2.0 1 1 0 1 1 1 1 AAA domain DUF2348 PF09807.4 ETO10011.1 - 0.0027 16.8 0.2 0.013 14.6 0.1 1.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) KAP_NTPase PF07693.9 ETO10011.1 - 0.0045 16.0 0.0 0.0055 15.7 0.0 1.3 1 1 0 1 1 1 1 KAP family P-loop domain AAA_33 PF13671.1 ETO10011.1 - 0.0093 15.8 0.3 0.076 12.8 0.2 2.2 1 1 0 1 1 1 1 AAA domain UPF0079 PF02367.12 ETO10011.1 - 0.021 14.4 0.0 0.06 12.9 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 ETO10011.1 - 0.024 14.9 0.6 0.052 13.8 0.1 1.8 2 0 0 2 2 2 0 ABC transporter PhoH PF02562.11 ETO10011.1 - 0.027 13.6 0.0 0.052 12.7 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.1 ETO10011.1 - 0.028 14.5 0.0 0.061 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 ETO10011.1 - 0.083 12.6 0.2 0.27 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ArgK PF03308.11 ETO10011.1 - 0.085 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 ArgK protein Zeta_toxin PF06414.7 ETO10011.1 - 0.098 11.7 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin T2SE PF00437.15 ETO10011.1 - 0.1 11.4 0.2 0.37 9.6 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA PF00004.24 ETO10011.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 ETO10011.1 - 0.13 11.9 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Tom37_C PF11801.3 ETO10012.1 - 0.0011 18.8 2.1 0.0087 15.9 0.0 2.3 1 1 1 2 2 2 1 Tom37 C-terminal domain GST_C_3 PF14497.1 ETO10012.1 - 0.0042 17.5 0.0 0.012 16.0 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETO10012.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain LRRC37AB_C PF14914.1 ETO10014.1 - 0.14 11.6 8.4 0.18 11.2 5.8 1.1 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Folate_carrier PF01770.13 ETO10014.1 - 0.52 8.7 3.7 0.55 8.6 2.6 1.1 1 0 0 1 1 1 0 Reduced folate carrier Mem_trans PF03547.13 ETO10014.1 - 0.74 8.0 5.0 0.81 7.9 3.4 1.1 1 0 0 1 1 1 0 Membrane transport protein FAM176 PF14851.1 ETO10014.1 - 1.1 8.8 7.7 1.9 8.1 5.3 1.4 1 0 0 1 1 1 0 FAM176 family NPR3 PF03666.8 ETO10014.1 - 2 6.8 17.5 0.35 9.3 9.9 1.3 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 DDHD PF02862.12 ETO10014.1 - 2.1 8.0 13.7 2.5 7.8 9.5 1.1 1 0 0 1 1 1 0 DDHD domain Serinc PF03348.10 ETO10014.1 - 2.8 6.5 5.9 2.9 6.5 4.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Zip PF02535.17 ETO10014.1 - 4.8 6.0 5.2 5.2 5.9 3.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SID-1_RNA_chan PF13965.1 ETO10014.1 - 7.5 4.5 11.2 8.1 4.4 7.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Peptidase_S10 PF00450.17 ETO10015.1 - 5.2e-17 62.1 1.6 2.6e-09 36.7 0.1 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase WD40 PF00400.27 ETO10016.1 - 1.4e-37 126.2 17.2 3.8e-10 39.2 0.3 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO10016.1 - 0.00056 18.1 5.3 0.61 8.1 0.1 3.3 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO10016.1 - 0.026 13.2 4.4 0.57 8.8 2.0 2.8 1 1 1 2 2 2 0 Nup133 N terminal like DUF4221 PF13970.1 ETO10016.1 - 0.052 12.8 4.1 0.18 11.0 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4221) Laminin_G_3 PF13385.1 ETO10017.1 - 6.1e-18 65.5 10.4 2.9e-17 63.3 0.4 3.1 2 1 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily WSC PF01822.14 ETO10017.1 - 3e-11 43.0 12.2 3e-11 43.0 8.4 2.5 3 0 0 3 3 3 1 WSC domain Laminin_G_2 PF02210.19 ETO10017.1 - 0.0024 17.9 0.7 0.022 14.8 0.1 2.7 2 0 0 2 2 2 1 Laminin G domain Lectin_C PF00059.16 ETO10017.1 - 0.017 15.7 2.0 0.017 15.7 1.4 3.2 4 0 0 4 4 4 0 Lectin C-type domain Aminotran_1_2 PF00155.16 ETO10017.1 - 0.027 13.4 0.0 0.048 12.6 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Sialidase PF02973.11 ETO10017.1 - 0.037 12.9 1.1 0.079 11.9 0.1 2.1 3 0 0 3 3 3 0 Sialidase, N-terminal domain Pkinase PF00069.20 ETO10018.1 - 0.0019 17.4 0.1 0.0046 16.1 0.1 1.7 1 0 0 1 1 1 1 Protein kinase domain NAD_binding_3 PF03447.11 ETO10018.1 - 0.0083 16.5 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain SH3BGR PF04908.10 ETO10018.1 - 0.033 14.1 4.3 3.2 7.7 0.2 2.5 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein DUF2229 PF09989.4 ETO10018.1 - 0.048 13.1 0.8 0.12 11.8 0.1 2.0 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) XK-related PF09815.4 ETO10019.1 - 8.9e-09 34.7 16.8 1.8e-08 33.7 7.8 3.1 2 1 0 2 2 2 1 XK-related protein DUF4337 PF14235.1 ETO10019.1 - 0.17 11.7 1.8 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) adh_short_C2 PF13561.1 ETO10020.1 - 2.1e-25 89.8 0.1 4e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETO10020.1 - 5.9e-25 88.1 0.4 5e-20 72.0 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 ETO10020.1 - 5.8e-05 22.8 1.0 0.00047 19.8 0.7 2.1 1 1 0 1 1 1 1 KR domain Sporozoite_P67 PF05642.6 ETO10020.1 - 0.00023 19.2 2.1 0.00023 19.2 1.5 1.6 2 0 0 2 2 2 1 Sporozoite P67 surface antigen SAPS PF04499.10 ETO10020.1 - 0.9 8.1 14.8 0.15 10.6 1.1 2.2 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Vfa1 PF08432.5 ETO10020.1 - 3.5 7.6 34.2 1.2 9.1 6.1 2.5 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 DUF1675 PF07897.6 ETO10020.1 - 3.9 7.2 14.9 0.5 10.1 3.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) Baculo_11_kDa PF06143.6 ETO10022.1 - 0.61 9.4 5.3 0.78 9.1 2.8 1.9 1 1 0 1 1 1 0 Baculovirus 11 kDa family G-alpha PF00503.15 ETO10024.1 - 4.2e-49 167.2 5.5 5.7e-27 94.4 0.3 2.1 2 0 0 2 2 2 2 G-protein alpha subunit Arf PF00025.16 ETO10024.1 - 4e-07 29.4 0.2 6.5e-06 25.5 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family DUF3048 PF11258.3 ETO10024.1 - 7.3e-05 22.0 0.0 0.00011 21.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3048) LYTB PF02401.13 ETO10024.1 - 0.00016 20.6 0.3 0.0002 20.3 0.2 1.0 1 0 0 1 1 1 1 LytB protein DUF3121 PF11319.3 ETO10024.1 - 0.047 13.1 0.3 0.099 12.1 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3121) LAGLIDADG_1 PF00961.14 ETO10024.1 - 0.22 12.1 6.0 0.83 10.2 3.1 2.2 2 0 0 2 2 2 0 LAGLIDADG endonuclease WD40 PF00400.27 ETO10025.1 - 4.4e-10 39.0 2.5 1.6e-09 37.2 0.1 2.7 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF1951 PF09188.5 ETO10025.1 - 0.011 15.6 0.1 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1951) MFS_2 PF13347.1 ETO10025.1 - 0.012 14.0 0.2 0.014 13.8 0.2 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein EF-hand_7 PF13499.1 ETO10026.1 - 3.3e-10 39.9 6.5 1.1e-08 35.0 0.5 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 ETO10026.1 - 6.1e-08 32.1 2.6 0.00033 20.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 ETO10026.1 - 6.6e-08 31.3 4.2 2.8e-05 23.0 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 ETO10026.1 - 4.6e-07 29.1 3.9 0.017 14.9 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 ETO10026.1 - 1.5e-06 27.3 3.3 2.1e-06 26.7 0.1 2.6 2 1 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.4 ETO10026.1 - 0.047 13.7 0.4 5.1 7.1 0.2 2.3 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region OGG_N PF07934.7 ETO10026.1 - 0.075 13.0 0.2 0.1 12.5 0.2 1.3 1 0 0 1 1 1 0 8-oxoguanine DNA glycosylase, N-terminal domain PRESAN PF09687.5 ETO10026.1 - 0.11 12.5 1.4 9.4 6.3 0.3 2.4 2 1 1 3 3 3 0 Plasmodium RESA N-terminal EF-hand_4 PF12763.2 ETO10026.1 - 0.2 11.4 1.7 2.2 8.0 0.5 2.1 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF3488 PF11992.3 ETO10027.1 - 0.013 14.1 0.0 0.017 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) Med2 PF11214.3 ETO10029.1 - 0.15 12.1 2.1 0.43 10.6 0.5 2.2 2 0 0 2 2 2 0 Mediator complex subunit 2 CAF1 PF04857.15 ETO10030.1 - 1.7e-15 57.0 0.0 5.5e-10 39.0 0.1 2.2 2 0 0 2 2 2 2 CAF1 family ribonuclease Prefoldin_2 PF01920.15 ETO10031.1 - 0.00081 19.1 0.2 0.0012 18.6 0.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit DUF2199 PF09965.4 ETO10032.1 - 0.0073 16.1 0.0 0.033 14.0 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2199) Rsc14 PF08586.5 ETO10033.1 - 0.24 11.8 1.0 0.38 11.2 0.3 1.6 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit Zip PF02535.17 ETO10034.1 - 0.00042 19.4 8.7 0.004 16.1 3.8 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter Dicty_REP PF05086.7 ETO10034.1 - 0.014 13.2 7.0 0.024 12.4 4.9 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 ETO10034.1 - 0.24 11.1 18.9 0.74 9.5 13.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SelP_N PF04592.9 ETO10034.1 - 0.62 9.3 23.7 0.1 11.9 9.7 2.3 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Macoilin PF09726.4 ETO10034.1 - 4.4 5.4 24.7 0.67 8.1 6.8 2.1 2 0 0 2 2 2 0 Transmembrane protein Tim54 PF11711.3 ETO10034.1 - 5.7 5.4 12.9 5.9 5.3 5.1 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Peptidase_S49_N PF08496.5 ETO10034.1 - 9.9 5.9 8.7 2.2 8.0 2.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Peptidase_M16 PF00675.15 ETO10037.1 - 1.3e-14 54.2 0.2 2.4e-14 53.3 0.1 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Lin-8 PF03353.10 ETO10037.1 - 0.15 11.2 4.9 0.18 11.0 3.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Drc1-Sld2 PF11719.3 ETO10037.1 - 0.28 10.2 11.7 0.38 9.7 8.1 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein DUF2457 PF10446.4 ETO10037.1 - 0.89 8.2 25.3 1.4 7.6 17.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Utp14 PF04615.8 ETO10037.1 - 1.3 7.0 16.9 1.6 6.8 11.7 1.1 1 0 0 1 1 1 0 Utp14 protein SDA1 PF05285.7 ETO10037.1 - 2.7 7.1 21.1 3.1 6.9 14.6 1.1 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.7 ETO10037.1 - 3.4 5.9 21.0 4 5.7 14.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) eIF-3c_N PF05470.7 ETO10037.1 - 4.7 5.1 13.0 5.7 4.9 9.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF2201_N PF13203.1 ETO10037.1 - 7.5 5.6 9.6 9.4 5.3 6.7 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Daxx PF03344.10 ETO10037.1 - 8.5 4.7 22.0 11 4.3 15.2 1.3 1 0 0 1 1 1 0 Daxx Family Mod_r PF07200.8 ETO10038.1 - 2.7e-10 40.3 9.3 1.2e-09 38.2 0.2 2.2 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein LPP PF04728.8 ETO10038.1 - 0.11 12.2 0.2 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Imm-NTF2 PF15655.1 ETO10038.1 - 0.13 12.7 4.3 0.65 10.4 0.5 2.2 2 0 0 2 2 2 0 NTF2 fold immunity protein BMF PF15185.1 ETO10038.1 - 0.19 11.0 0.5 0.32 10.2 0.3 1.3 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis Cytochrom_B562 PF07361.6 ETO10038.1 - 0.21 12.0 2.8 0.83 10.1 0.0 2.3 2 1 0 2 2 2 0 Cytochrome b562 Occludin_ELL PF07303.8 ETO10038.1 - 0.31 11.7 5.3 4 8.2 0.6 2.2 2 0 0 2 2 2 0 Occludin homology domain rRNA_proc-arch PF13234.1 ETO10038.1 - 0.53 9.4 5.5 2.5 7.1 0.3 2.1 2 0 0 2 2 2 0 rRNA-processing arch domain Seryl_tRNA_N PF02403.17 ETO10038.1 - 0.54 10.2 4.1 1.6 8.7 0.9 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain BLOC1_2 PF10046.4 ETO10038.1 - 0.88 9.7 5.5 1.1 9.3 0.3 2.5 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_1 PF00170.16 ETO10038.1 - 1.4 8.9 5.8 2 8.4 0.5 2.4 2 0 0 2 2 2 0 bZIP transcription factor GTP_EFTU PF00009.22 ETO10038.1 - 1.5 8.2 6.5 13 5.2 4.5 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain YlqD PF11068.3 ETO10038.1 - 1.5 8.8 9.1 1.2 9.1 0.1 2.3 2 1 0 2 2 2 0 YlqD protein DUF2024 PF09630.5 ETO10040.1 - 0.094 12.4 5.7 0.19 11.4 3.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF2024) RPAP3_C PF13877.1 ETO10042.1 - 0.00069 19.5 1.5 1.1 9.2 0.1 3.2 3 0 0 3 3 3 2 Potential Monad-binding region of RPAP3 DUF3021 PF11457.3 ETO10042.1 - 0.067 13.0 2.4 0.14 12.0 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) Tat PF00539.13 ETO10042.1 - 0.077 12.6 0.3 0.23 11.1 0.2 1.8 1 0 0 1 1 1 0 Transactivating regulatory protein (Tat) Sad1_UNC PF07738.8 ETO10043.1 - 2.5e-14 53.2 1.0 3.2e-13 49.6 0.1 2.7 2 1 0 2 2 2 1 Sad1 / UNC-like C-terminal RRF PF01765.14 ETO10044.1 - 0.0083 15.6 3.8 0.0083 15.6 2.6 1.7 2 0 0 2 2 2 1 Ribosome recycling factor Fe-S_assembly PF04384.8 ETO10044.1 - 0.0084 16.4 3.1 0.014 15.7 2.1 1.5 1 0 0 1 1 1 1 Iron-sulphur cluster assembly Laminin_II PF06009.7 ETO10044.1 - 0.015 15.0 0.8 0.015 15.0 0.6 2.0 2 0 0 2 2 2 0 Laminin Domain II DUF349 PF03993.7 ETO10044.1 - 0.031 14.4 0.5 0.031 14.4 0.4 2.7 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) IncA PF04156.9 ETO10044.1 - 0.051 13.1 15.3 0.069 12.7 10.2 1.7 1 1 0 1 1 1 0 IncA protein Ribosomal_S8e PF01201.17 ETO10044.1 - 0.061 13.4 1.9 0.085 12.9 1.3 1.2 1 0 0 1 1 1 0 Ribosomal protein S8e Med11 PF10280.4 ETO10044.1 - 0.48 10.4 7.6 0.048 13.7 1.9 1.9 2 0 0 2 2 2 0 Mediator complex protein Ras PF00071.17 ETO10046.1 - 2.7e-45 153.6 0.0 3.9e-45 153.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO10046.1 - 1.3e-14 54.6 0.0 2.4e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO10046.1 - 1.2e-06 27.8 0.0 1.8e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO10046.1 - 3.8e-05 23.2 0.0 6.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain PaRep2a PF07903.6 ETO10047.1 - 0.046 13.3 0.4 1.8 8.2 0.0 2.2 2 0 0 2 2 2 0 PaRep2a protein DUF3372 PF11852.3 ETO10048.1 - 0.018 14.1 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) RPM2 PF08579.6 ETO10048.1 - 0.11 12.6 0.2 0.13 12.4 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) NPIP PF06409.6 ETO10049.1 - 0.24 10.1 2.8 1.3 7.7 0.0 2.2 2 0 0 2 2 2 0 Nuclear pore complex interacting protein (NPIP) PI3K_1B_p101 PF10486.4 ETO10051.1 - 1e-11 43.2 0.1 7e-07 27.2 0.0 2.3 2 1 0 2 2 2 2 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pacs-1 PF10254.4 ETO10051.1 - 0.02 13.5 2.6 0.021 13.5 0.0 2.0 2 0 0 2 2 2 0 PACS-1 cytosolic sorting protein Cas_CT1975 PF09344.5 ETO10051.1 - 0.041 13.2 0.7 0.063 12.6 0.5 1.2 1 0 0 1 1 1 0 CT1975-like protein Peptidase_M48 PF01435.13 ETO10052.1 - 5.9e-24 84.8 0.0 9.9e-24 84.1 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M48 TraH PF06122.6 ETO10052.1 - 0.2 10.4 1.2 0.3 9.8 0.8 1.2 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein DUF2201_N PF13203.1 ETO10052.1 - 0.22 10.6 2.2 5.2 6.1 0.1 2.2 2 0 0 2 2 2 0 Putative metallopeptidase domain YqfQ PF14181.1 ETO10052.1 - 1.1 9.2 5.0 2.1 8.3 3.5 1.4 1 0 0 1 1 1 0 YqfQ-like protein Pkinase PF00069.20 ETO10053.1 - 5.4e-54 183.0 0.0 7.7e-54 182.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO10053.1 - 1.4e-24 86.6 0.0 1.9e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 ETO10053.1 - 2.4e-22 76.4 10.3 1e-08 33.8 0.4 4.7 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 ETO10053.1 - 2.1e-16 59.7 16.5 2.4e-10 40.3 0.6 3.4 4 0 0 4 4 3 2 EF-hand domain pair EF-hand_5 PF13202.1 ETO10053.1 - 3.1e-13 48.3 10.1 2e-06 26.8 0.3 3.9 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 ETO10053.1 - 4e-13 48.0 20.0 2e-05 24.0 0.2 5.7 6 0 0 6 6 6 4 EF-hand domain EF-hand_8 PF13833.1 ETO10053.1 - 1.6e-11 43.5 10.7 0.00043 19.8 0.2 4.3 2 1 2 4 4 4 3 EF-hand domain pair APH PF01636.18 ETO10053.1 - 2.8e-05 23.9 0.2 0.00015 21.5 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 ETO10053.1 - 5.2e-05 22.6 0.3 0.00011 21.6 0.2 1.5 1 0 0 1 1 1 1 RIO1 family SPARC_Ca_bdg PF10591.4 ETO10053.1 - 0.0018 18.3 1.8 0.19 11.7 0.1 2.8 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Choline_kinase PF01633.15 ETO10053.1 - 0.0035 16.9 2.0 0.0083 15.7 0.2 2.4 2 2 0 2 2 2 1 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 ETO10053.1 - 0.004 16.0 0.1 0.004 16.0 0.1 1.8 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.4 ETO10053.1 - 0.0064 15.8 0.1 0.023 14.0 0.0 1.9 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kdo PF06293.9 ETO10053.1 - 0.0078 15.2 0.1 0.013 14.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_4 PF12763.2 ETO10053.1 - 0.016 14.9 2.5 0.21 11.3 0.1 2.7 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand SUA5 PF03481.8 ETO10053.1 - 0.058 13.4 0.3 0.23 11.5 0.2 2.0 1 1 0 1 1 1 0 Putative GTP-binding controlling metal-binding LisH PF08513.6 ETO10053.1 - 0.11 12.2 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 LisH EFhand_Ca_insen PF08726.5 ETO10053.1 - 0.24 11.4 2.1 0.26 11.3 0.3 1.9 2 0 0 2 2 1 0 Ca2+ insensitive EF hand Arf PF00025.16 ETO10054.1 - 9.1e-06 25.0 0.0 1.3e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF3911 PF13050.1 ETO10054.1 - 0.27 11.3 0.1 0.27 11.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3911) RNase_PH PF01138.16 ETO10056.1 - 0.56 10.5 4.7 5.3 7.3 0.3 2.6 2 0 0 2 2 2 0 3' exoribonuclease family, domain 1 DUF1325 PF07039.6 ETO10056.1 - 9.6 5.8 14.6 0.066 12.8 1.2 3.1 2 1 1 3 3 3 0 SGF29 tudor-like domain DUF3382 PF11862.3 ETO10057.1 - 0.015 15.2 0.1 0.036 13.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) DUF2453 PF10507.4 ETO10057.1 - 0.016 15.0 0.1 0.029 14.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2453) DSPc PF00782.15 ETO10058.1 - 8.7e-21 73.8 0.1 6.5e-20 71.0 0.0 2.1 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 ETO10058.1 - 0.0096 15.9 0.9 0.12 12.4 0.0 2.7 2 1 1 3 3 3 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 ETO10058.1 - 0.03 13.6 0.8 0.08 12.2 0.0 2.0 1 1 1 2 2 2 0 Protein-tyrosine phosphatase Spore_III_AB PF09548.5 ETO10058.1 - 0.053 13.2 0.4 0.1 12.3 0.3 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) zf-C3HC4_3 PF13920.1 ETO10059.1 - 4.6e-09 35.8 8.5 4.6e-09 35.8 5.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAM_PNT PF02198.11 ETO10059.1 - 0.001 18.7 0.4 0.0025 17.5 0.3 1.7 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_2 PF07647.12 ETO10059.1 - 0.0013 18.5 1.5 0.0044 16.8 1.1 2.0 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) FGF PF00167.13 ETO10059.1 - 0.0017 18.1 0.0 0.015 15.0 0.0 2.3 1 1 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.8 ETO10059.1 - 0.0037 17.3 0.5 0.018 15.1 0.2 2.2 1 1 1 2 2 2 1 Fascin domain DUF948 PF06103.6 ETO10059.1 - 0.038 13.8 4.6 0.17 11.7 3.1 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) zf-C3HC4_2 PF13923.1 ETO10059.1 - 0.055 13.4 17.2 0.099 12.6 9.1 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) IncA PF04156.9 ETO10059.1 - 0.31 10.6 17.9 0.49 9.9 11.6 2.0 1 1 0 1 1 1 0 IncA protein NPV_P10 PF05531.7 ETO10059.1 - 0.63 10.3 11.2 0.74 10.1 3.2 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein ERM PF00769.14 ETO10059.1 - 1.6 8.1 16.7 0.13 11.8 6.5 2.5 1 1 1 2 2 2 0 Ezrin/radixin/moesin family ATG16 PF08614.6 ETO10059.1 - 2.8 7.7 19.9 7.6 6.3 9.0 3.0 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Adeno_terminal PF02459.10 ETO10060.1 - 0.089 10.9 0.3 0.13 10.4 0.2 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein PI3K_C2 PF00792.19 ETO10061.1 - 1.6e-08 34.4 0.1 0.00033 20.4 0.0 2.5 2 0 0 2 2 2 2 Phosphoinositide 3-kinase C2 PolyA_pol_arg_C PF12626.2 ETO10061.1 - 0.044 13.4 0.0 0.044 13.4 0.0 2.5 3 0 0 3 3 3 0 Polymerase A arginine-rich C-terminus Usp PF00582.21 ETO10062.1 - 0.12 12.5 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 Universal stress protein family DUF1250 PF06855.7 ETO10062.1 - 0.13 11.7 0.2 0.25 10.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1250) DUF912 PF06024.7 ETO10062.1 - 0.29 11.1 1.3 0.61 10.1 0.9 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) WD40 PF00400.27 ETO10064.1 - 3.7e-65 213.6 25.4 7e-13 47.9 0.1 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO10064.1 - 1.7e-06 26.5 4.0 0.075 11.1 0.2 4.2 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO10064.1 - 0.00024 19.5 0.1 1 7.6 0.0 3.0 1 1 2 3 3 3 3 Cytochrome D1 heme domain DUF3732 PF12532.3 ETO10064.1 - 0.17 11.3 1.5 12 5.4 0.0 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF3732) Resistin PF06954.6 ETO10064.1 - 0.89 9.8 4.2 11 6.3 0.1 3.6 2 2 0 3 3 3 0 Resistin Annexin PF00191.15 ETO10065.1 - 8.2e-20 70.4 5.7 1.5e-08 34.3 0.1 4.8 4 1 0 4 4 4 4 Annexin Leu_Phe_trans PF03588.9 ETO10065.1 - 0.009 15.1 0.0 0.037 13.1 0.0 2.0 2 0 0 2 2 2 1 Leucyl/phenylalanyl-tRNA protein transferase Acetyltransf_4 PF13420.1 ETO10065.1 - 0.17 11.8 2.5 0.57 10.1 0.1 2.7 2 1 1 3 3 3 0 Acetyltransferase (GNAT) domain LRR_6 PF13516.1 ETO10066.1 - 2.8e-05 23.7 5.6 2.3 8.5 0.1 4.8 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.2 ETO10066.1 - 0.0011 18.5 6.5 0.16 11.6 0.1 3.8 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETO10066.1 - 0.0054 16.5 3.6 8.8 6.8 0.0 4.5 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_7 PF13504.1 ETO10066.1 - 0.2 11.9 3.4 64 4.4 0.0 4.4 4 0 0 4 4 4 0 Leucine rich repeat zf-RING_2 PF13639.1 ETO10067.1 - 1e-05 25.2 4.5 1e-05 25.2 3.1 4.1 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO10067.1 - 3.5e-05 23.7 1.7 3.5e-05 23.7 1.1 4.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO10067.1 - 4.2e-05 23.1 6.6 4.2e-05 23.1 4.6 5.0 4 2 0 4 4 4 1 zinc-RING finger domain zf-rbx1 PF12678.2 ETO10067.1 - 6.6e-05 22.9 24.5 0.0021 18.1 0.7 3.7 3 0 0 3 3 3 2 RING-H2 zinc finger zf-C3HC4 PF00097.20 ETO10067.1 - 7.4e-05 22.3 5.3 7.4e-05 22.3 3.7 4.7 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 ETO10067.1 - 0.00054 19.6 11.1 0.017 14.8 0.6 4.2 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 ETO10067.1 - 0.001 18.8 2.4 0.001 18.8 1.7 5.0 6 0 0 6 6 6 1 zinc finger of C3HC4-type, RING CPSF100_C PF13299.1 ETO10067.1 - 2.8 8.0 10.1 9 6.4 0.1 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal UPF0233 PF06781.7 ETO10068.1 - 0.02 14.4 1.3 0.096 12.3 0.0 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) mit_SMPDase PF14724.1 ETO10069.1 - 0.027 12.3 0.1 0.036 11.8 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial-associated sphingomyelin phosphodiesterase DUF1183 PF06682.7 ETO10069.1 - 0.075 12.6 0.1 0.075 12.6 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) Presenilin PF01080.12 ETO10069.1 - 0.11 11.3 0.3 0.15 10.8 0.2 1.1 1 0 0 1 1 1 0 Presenilin Cu-oxidase_3 PF07732.10 ETO10070.1 - 5.6e-07 29.3 1.1 1.6e-06 27.8 0.8 1.7 1 1 0 1 1 1 1 Multicopper oxidase Adaptin_N PF01602.15 ETO10071.1 - 1.6e-19 69.6 1.5 2.1e-19 69.2 1.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region SRP_SPB PF02978.14 ETO10071.1 - 1.1 9.5 5.4 5.6 7.2 3.7 2.2 1 1 0 1 1 1 0 Signal peptide binding domain FMN_red PF03358.10 ETO10072.1 - 0.0024 17.4 0.0 0.0036 16.8 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase FliP PF00813.15 ETO10073.1 - 0.11 12.2 0.4 0.16 11.6 0.3 1.2 1 0 0 1 1 1 0 FliP family Mucin PF01456.12 ETO10073.1 - 0.22 11.2 31.6 0.42 10.3 21.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.7 ETO10073.1 - 5.6 4.5 22.9 11 3.6 15.9 1.5 1 1 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4234 PF14018.1 ETO10074.1 - 0.0016 18.1 1.6 0.0016 18.1 1.1 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4234) DUF202 PF02656.10 ETO10074.1 - 0.24 11.6 5.7 1.6 8.9 0.2 2.8 2 1 0 3 3 3 0 Domain of unknown function (DUF202) Prominin PF05478.6 ETO10074.1 - 0.52 7.7 8.6 0.73 7.2 5.9 1.2 1 0 0 1 1 1 0 Prominin DUF2207 PF09972.4 ETO10074.1 - 6 5.3 7.5 20 3.6 5.1 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Cu-oxidase_2 PF07731.9 ETO10075.1 - 8.9e-13 47.9 0.2 3.1e-12 46.1 0.1 1.8 2 0 0 2 2 2 1 Multicopper oxidase WTF PF03303.8 ETO10075.1 - 0.71 9.2 5.5 1.1 8.6 3.8 1.2 1 0 0 1 1 1 0 WTF protein CAP_GLY PF01302.20 ETO10076.1 - 4.4e-44 148.0 7.5 5.4e-24 83.6 0.3 3.0 3 0 0 3 3 3 2 CAP-Gly domain Tmemb_40 PF10160.4 ETO10078.1 - 0.036 13.3 0.3 0.074 12.2 0.0 1.6 2 0 0 2 2 2 0 Predicted membrane protein Ribosomal_L38e PF01781.13 ETO10078.1 - 0.088 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Ribosomal L38e protein family Bromodomain PF00439.20 ETO10079.1 - 3.1e-08 33.4 0.0 5.7e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Bromodomain Spore_coat_CotO PF14153.1 ETO10080.1 - 0.0085 15.5 2.2 0.0094 15.4 1.5 1.1 1 0 0 1 1 1 1 Spore coat protein CotO SAPS PF04499.10 ETO10080.1 - 0.017 13.7 3.0 0.019 13.6 2.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Trypan_PARP PF05887.6 ETO10080.1 - 0.043 13.6 17.7 0.06 13.1 12.3 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Daxx PF03344.10 ETO10080.1 - 0.25 9.8 20.2 0.32 9.4 14.0 1.0 1 0 0 1 1 1 0 Daxx Family TRAP_alpha PF03896.11 ETO10080.1 - 0.3 10.0 7.0 0.54 9.2 4.9 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.7 ETO10080.1 - 0.5 8.2 22.7 0.63 7.8 15.7 1.0 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 ETO10080.1 - 0.53 9.6 17.5 0.86 8.9 12.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DNA_pol_phi PF04931.8 ETO10080.1 - 0.64 7.7 22.6 0.91 7.2 15.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.9 ETO10080.1 - 0.66 7.9 14.4 0.84 7.5 10.0 1.1 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.8 ETO10080.1 - 0.95 7.9 9.7 1.3 7.4 6.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Lin-8 PF03353.10 ETO10080.1 - 1.1 8.4 10.1 1.9 7.7 6.7 1.6 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF3449 PF11931.3 ETO10080.1 - 1.5 8.2 16.4 11 5.4 11.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3449) Hid1 PF12722.2 ETO10080.1 - 2.6 5.6 10.6 4.6 4.8 7.3 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RP-C_C PF11800.3 ETO10080.1 - 3.6 7.2 6.5 4.9 6.8 4.5 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Pox_Ag35 PF03286.9 ETO10080.1 - 8.3 5.8 16.8 12 5.4 11.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4519 PF15012.1 ETO10081.1 - 3.4 7.6 6.9 9.9 6.1 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) BUD22 PF09073.5 ETO10082.1 - 0.8 8.7 47.1 1.4 7.8 32.6 1.4 1 0 0 1 1 1 0 BUD22 BatD PF13584.1 ETO10083.1 - 0.02 13.5 0.1 0.021 13.4 0.1 1.0 1 0 0 1 1 1 0 Oxygen tolerance ubiquitin PF00240.18 ETO10083.1 - 0.035 13.5 0.8 0.095 12.1 0.5 1.7 1 1 0 1 1 1 0 Ubiquitin family CcmH PF03918.9 ETO10083.1 - 0.086 11.8 0.0 7.1 5.6 0.0 2.2 2 0 0 2 2 2 0 Cytochrome C biogenesis protein MC1 PF05854.6 ETO10083.1 - 0.12 12.3 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Non-histone chromosomal protein MC1 Sulfatase PF00884.18 ETO10084.1 - 2.6e-57 194.3 1.0 3.2e-57 194.0 0.7 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 ETO10084.1 - 9.5e-09 35.0 0.6 3.4e-07 29.9 0.4 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.7 ETO10084.1 - 0.019 13.8 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Cation_ATPase_N PF00690.21 ETO10084.1 - 0.13 11.7 0.1 0.25 10.8 0.1 1.4 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus tRNA-synt_1b PF00579.20 ETO10085.1 - 1.7e-24 86.4 0.1 4.1e-24 85.2 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) PH PF00169.24 ETO10085.1 - 3.5e-07 30.3 2.3 1.2e-06 28.6 1.6 2.1 1 1 0 1 1 1 1 PH domain PH_6 PF15406.1 ETO10085.1 - 0.044 13.8 0.1 0.14 12.2 0.1 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain NOGCT PF08155.6 ETO10085.1 - 0.066 12.9 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 NOGCT (NUC087) domain SlyX PF04102.7 ETO10086.1 - 1.3 9.4 11.1 0.091 13.1 3.2 2.1 2 0 0 2 2 2 0 SlyX ERp29 PF07749.7 ETO10087.1 - 6.7e-22 77.9 0.4 1.1e-21 77.1 0.3 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain ERp29_N PF07912.8 ETO10087.1 - 6.5e-08 32.5 0.1 1.8e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 ERp29, N-terminal domain Abhydrolase_5 PF12695.2 ETO10088.1 - 6e-07 29.3 0.0 9e-07 28.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETO10088.1 - 0.022 14.6 0.0 0.24 11.2 0.0 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family DUF2986 PF11661.3 ETO10088.1 - 3.2 8.1 6.2 5.4 7.4 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2986) WW PF00397.21 ETO10089.1 - 0.68 9.8 3.9 1.2 9.1 2.7 1.4 1 0 0 1 1 1 0 WW domain YMF19 PF02326.10 ETO10090.1 - 0.018 15.5 0.6 0.018 15.5 0.4 1.8 2 0 0 2 2 2 0 Plant ATP synthase F0 C2 PF00168.25 ETO10091.1 - 1.3e-11 44.1 0.2 3.5e-11 42.7 0.1 1.7 1 0 0 1 1 1 1 C2 domain UBA PF00627.26 ETO10091.1 - 0.068 13.0 0.0 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 UBA/TS-N domain zf-RanBP PF00641.13 ETO10091.1 - 0.16 11.0 1.8 0.35 10.0 1.2 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Thioredoxin_8 PF13905.1 ETO10092.1 - 0.044 13.9 1.0 0.06 13.4 0.6 1.4 1 1 0 1 1 1 0 Thioredoxin-like Ilar_coat PF01787.11 ETO10093.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.5 1 1 0 1 1 1 0 Ilarvirus coat protein KH_3 PF13014.1 ETO10094.1 - 0.0004 19.9 0.1 0.0013 18.2 0.1 2.0 1 0 0 1 1 1 1 KH domain KH_1 PF00013.24 ETO10094.1 - 0.00062 19.3 0.4 0.0018 17.8 0.0 1.9 2 0 0 2 2 2 1 KH domain zf-CCHC_2 PF13696.1 ETO10094.1 - 0.024 14.1 7.5 0.06 12.8 0.2 2.8 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.1 ETO10094.1 - 0.11 12.2 4.7 0.5 10.1 0.0 2.4 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 ETO10094.1 - 2.6 7.8 8.4 12 5.6 1.2 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.18 ETO10094.1 - 4.5 7.3 7.9 4.2 7.4 1.1 2.5 2 0 0 2 2 2 0 Zinc knuckle Nha1_C PF08619.5 ETO10096.1 - 2.1e-05 23.9 6.4 2.1e-05 23.9 4.5 2.1 2 0 0 2 2 2 1 Alkali metal cation/H+ antiporter Nha1 C terminus CDC45 PF02724.9 ETO10096.1 - 0.00014 20.1 10.1 0.00014 20.1 7.0 2.6 3 0 0 3 3 3 1 CDC45-like protein Hid1 PF12722.2 ETO10096.1 - 0.03 12.0 36.8 0.003 15.3 5.7 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Daxx PF03344.10 ETO10096.1 - 0.051 12.0 38.9 0.048 12.1 6.0 2.1 2 0 0 2 2 2 0 Daxx Family Pox_Ag35 PF03286.9 ETO10096.1 - 0.24 10.8 41.6 0.58 9.6 16.7 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF2201_N PF13203.1 ETO10096.1 - 3 6.9 23.0 2.3 7.3 3.8 2.3 2 0 0 2 2 2 0 Putative metallopeptidase domain GEMIN8 PF15348.1 ETO10096.1 - 8.8 6.3 35.7 4.1 7.4 6.8 2.5 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 Mitofilin PF09731.4 ETO10097.1 - 0.055 12.1 4.0 0.021 13.4 0.7 1.6 2 0 0 2 2 2 0 Mitochondrial inner membrane protein MGDG_synth PF06925.6 ETO10097.1 - 0.086 12.7 0.1 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase RRM_6 PF14259.1 ETO10098.1 - 0.00013 21.8 0.0 0.00031 20.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO10098.1 - 0.0016 18.0 0.0 0.026 14.1 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF188 PF02639.9 ETO10098.1 - 0.15 11.4 0.2 3.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized BCR, YaiI/YqxD family COG1671 Acyltransferase PF01553.16 ETO10099.1 - 1.7e-11 43.7 0.0 4.1e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase Vma12 PF11712.3 ETO10099.1 - 0.036 13.7 0.1 0.075 12.7 0.1 1.5 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Peptidase_A25 PF03418.9 ETO10099.1 - 0.1 11.3 0.1 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Germination protease PAXIP1_C PF15364.1 ETO10102.1 - 0.26 11.1 0.1 0.26 11.1 0.1 2.1 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein F-box-like PF12937.2 ETO10104.1 - 0.017 14.8 0.5 0.039 13.6 0.4 1.6 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 ETO10104.1 - 1.1 8.9 4.7 2.6 7.7 2.1 2.4 2 1 0 2 2 2 0 F-box domain Ins134_P3_kin PF05770.6 ETO10105.1 - 1.3e-09 37.4 0.7 3.3e-08 32.8 0.0 2.6 2 1 1 3 3 3 1 Inositol 1, 3, 4-trisphosphate 5/6-kinase YhfZ_C PF14503.1 ETO10105.1 - 0.19 11.0 1.9 0.31 10.3 1.3 1.2 1 0 0 1 1 1 0 YhfZ C-terminal domain ETRAMP PF09716.5 ETO10105.1 - 0.41 10.6 11.7 1.2 9.0 0.3 3.0 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF3753 PF12575.3 ETO10105.1 - 1.5 8.6 9.7 0.06 13.1 1.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3753) GRP PF07172.6 ETO10106.1 - 0.03 14.8 14.7 0.041 14.3 10.2 1.2 1 0 0 1 1 1 0 Glycine rich protein family PH PF00169.24 ETO10107.1 - 0.01 16.0 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 0 PH domain Sigma70_ner PF04546.8 ETO10107.1 - 0.016 14.8 3.1 0.026 14.1 2.2 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Mg_trans_NIPA PF05653.9 ETO10108.1 - 2.5e-06 26.7 4.9 4.5e-06 25.8 0.1 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA Cu-oxidase_2 PF07731.9 ETO10109.1 - 1.2e-08 34.5 1.9 3.6e-08 33.0 1.3 1.7 1 1 0 1 1 1 1 Multicopper oxidase DUF3757 PF12582.3 ETO10109.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3757) CAP_GLY PF01302.20 ETO10110.1 - 2.9e-22 78.1 0.8 7.6e-21 73.5 0.3 2.5 2 0 0 2 2 2 1 CAP-Gly domain TRP PF06011.7 ETO10110.1 - 0.0069 15.0 0.0 0.013 14.1 0.0 1.3 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel 4HBT PF03061.17 ETO10111.1 - 2.7e-11 43.4 0.0 4.5e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 2OG-FeII_Oxy_3 PF13640.1 ETO10112.1 - 2e-13 50.7 0.0 3.6e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 ETO10112.1 - 0.0054 16.9 0.1 0.037 14.3 0.1 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TauD PF02668.11 ETO10112.1 - 0.011 15.4 0.1 0.12 12.0 0.0 2.3 2 1 1 3 3 3 0 Taurine catabolism dioxygenase TauD, TfdA family AMP-binding PF00501.23 ETO10115.1 - 1.3e-13 50.1 0.0 1.9e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ubiquitin PF00240.18 ETO10115.1 - 0.16 11.3 3.3 2.7 7.4 0.1 3.3 4 0 0 4 4 4 0 Ubiquitin family YMF19 PF02326.10 ETO10115.1 - 7.4 7.2 9.9 13 6.4 0.5 2.5 2 0 0 2 2 2 0 Plant ATP synthase F0 C2 PF00168.25 ETO10117.1 - 1.2e-14 53.8 0.7 3.5e-14 52.3 0.1 2.2 2 0 0 2 2 2 1 C2 domain TRAP_alpha PF03896.11 ETO10118.1 - 0.00057 18.9 7.8 0.00057 18.9 5.4 4.4 3 2 1 4 4 4 1 Translocon-associated protein (TRAP), alpha subunit DUF1510 PF07423.6 ETO10118.1 - 0.0021 17.4 6.3 0.0021 17.4 4.3 5.2 4 1 0 4 4 4 2 Protein of unknown function (DUF1510) MLANA PF14991.1 ETO10118.1 - 0.12 12.3 0.3 1.2 9.1 0.0 2.6 2 0 0 2 2 2 0 Protein melan-A TPR_12 PF13424.1 ETO10119.1 - 8.2e-05 22.4 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO10119.1 - 0.022 14.3 0.1 0.31 10.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETO10119.1 - 0.056 13.2 0.0 0.19 11.5 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETO10119.1 - 0.1 12.5 0.0 0.71 9.9 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat KA1 PF02149.14 ETO10120.1 - 0.00015 21.1 0.3 0.00039 19.7 0.0 1.7 2 0 0 2 2 2 1 Kinase associated domain 1 Pkinase PF00069.20 ETO10120.1 - 0.0051 16.0 0.9 0.01 14.9 0.0 1.9 3 0 0 3 3 3 1 Protein kinase domain Chromo PF00385.19 ETO10121.1 - 5.6e-15 54.7 0.5 1.4e-14 53.5 0.3 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mucin PF01456.12 ETO10122.1 - 0.12 12.1 8.1 0.16 11.7 5.6 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.6 ETO10122.1 - 0.94 7.3 6.0 1.5 6.7 4.2 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 ETO10122.1 - 1.7 8.4 5.8 3.7 7.3 4.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) zf-DHHC PF01529.15 ETO10123.1 - 1.1e-36 125.7 15.8 1.1e-36 125.7 10.9 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF973 PF06157.6 ETO10123.1 - 0.011 14.7 0.5 0.022 13.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF2254 PF10011.4 ETO10123.1 - 0.1 11.0 0.0 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) YgbA_NO PF11756.3 ETO10124.1 - 0.01 15.8 2.3 0.021 14.8 1.6 1.5 1 0 0 1 1 1 0 Nitrous oxide-stimulated promoter mRNA_cap_C PF03919.10 ETO10124.1 - 0.032 14.5 0.2 0.052 13.8 0.1 1.5 1 1 0 1 1 1 0 mRNA capping enzyme, C-terminal domain PPP5 PF08321.7 ETO10124.1 - 0.098 12.6 1.0 7.7 6.6 0.2 2.1 2 0 0 2 2 2 0 PPP5 TPR repeat region DisA-linker PF10635.4 ETO10125.1 - 0.011 15.2 0.1 0.011 15.2 0.1 2.2 3 1 0 3 3 3 0 DisA bacterial checkpoint controller linker region Mrr_N PF14338.1 ETO10125.1 - 0.039 14.0 3.2 3.3 7.8 0.0 3.4 2 1 1 3 3 3 0 Mrr N-terminal domain Fer4_14 PF13394.1 ETO10125.1 - 0.08 12.9 0.0 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 4Fe-4S single cluster domain Ribosomal_L36e PF01158.13 ETO10125.1 - 6.2 6.8 9.5 0.95 9.4 3.2 2.1 2 0 0 2 2 2 0 Ribosomal protein L36e LRR_6 PF13516.1 ETO10127.1 - 0.033 14.2 0.9 0.28 11.3 0.1 2.6 2 1 0 2 2 2 0 Leucine Rich repeat SAS4 PF15460.1 ETO10127.1 - 0.045 13.6 0.3 0.073 12.9 0.2 1.3 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 LRR_4 PF12799.2 ETO10127.1 - 0.13 11.8 4.4 0.12 12.0 0.5 2.7 2 2 0 2 2 2 0 Leucine Rich repeats (2 copies) Ribosomal_S20p PF01649.13 ETO10128.1 - 0.22 11.9 4.2 0.29 11.5 1.1 2.5 2 1 0 2 2 2 0 Ribosomal protein S20 Ctr PF04145.10 ETO10129.1 - 0.086 12.8 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Ctr copper transporter family TFIIA PF03153.8 ETO10132.1 - 0.0059 16.5 24.8 0.0059 16.5 17.2 2.5 1 1 1 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF3439 PF11921.3 ETO10132.1 - 2.3 7.9 6.5 0.84 9.3 1.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) TFIIF_alpha PF05793.7 ETO10132.1 - 2.9 6.1 59.2 4 5.7 41.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Hid1 PF12722.2 ETO10132.1 - 6.6 4.2 26.9 8.5 3.9 18.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAZ PF02170.17 ETO10134.1 - 1.2e-05 24.6 1.2 3.2e-05 23.2 0.1 2.1 1 1 0 2 2 2 1 PAZ domain FF PF01846.14 ETO10136.1 - 0.00025 20.9 0.1 0.00025 20.9 0.1 3.1 2 2 2 4 4 4 1 FF domain DUF3786 PF12654.2 ETO10136.1 - 0.044 13.0 0.1 0.055 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) DUF1356 PF07092.7 ETO10136.1 - 0.049 12.8 0.0 0.075 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) M11L PF11099.3 ETO10136.1 - 0.055 13.1 1.3 0.63 9.7 0.0 2.1 2 0 0 2 2 2 0 Apoptosis regulator M11L like HTH_40 PF14493.1 ETO10136.1 - 0.32 11.2 3.6 1.1 9.4 0.3 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain DUF1539 PF07560.6 ETO10136.1 - 0.54 10.1 5.8 0.2 11.5 1.4 2.0 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1539) DUF2924 PF11149.3 ETO10136.1 - 0.64 10.0 3.4 14 5.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2924) DUF464 PF04327.7 ETO10136.1 - 0.83 9.9 4.4 0.29 11.3 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF464) RNA_pol_Rpb1_4 PF05000.12 ETO10136.1 - 0.97 9.2 5.9 1 9.1 1.3 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 4 FF PF01846.14 ETO10137.1 - 1.5e-13 50.4 5.5 5.8e-11 42.1 0.5 2.9 1 1 1 2 2 2 2 FF domain Lip_A_acyltrans PF03279.8 ETO10137.1 - 0.011 14.5 0.7 0.025 13.4 0.1 1.6 1 1 1 2 2 2 0 Bacterial lipid A biosynthesis acyltransferase MRP-S24 PF14955.1 ETO10137.1 - 0.076 12.8 1.3 0.083 12.7 0.2 1.6 1 1 1 2 2 2 0 Mitochondrial ribosome subunit S24 Lipase_GDSL_3 PF14606.1 ETO10137.1 - 0.097 12.3 0.6 0.14 11.8 0.4 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DUF1911 PF08929.5 ETO10137.1 - 0.24 12.0 4.9 0.5 11.0 3.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1911) DUF445 PF04286.7 ETO10137.1 - 0.28 10.6 5.0 0.32 10.4 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF2115 PF09888.4 ETO10137.1 - 0.33 11.0 4.7 0.45 10.5 3.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) SecA_DEAD PF07517.9 ETO10137.1 - 3.8 6.7 5.7 1.1 8.4 0.9 1.9 1 1 1 2 2 2 0 SecA DEAD-like domain HATPase_c PF02518.21 ETO10139.1 - 7.4e-15 54.6 0.0 7.8e-14 51.3 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 ETO10139.1 - 9e-05 22.1 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4534 PF15049.1 ETO10140.1 - 0.0092 15.6 2.9 0.0092 15.6 2.0 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF4534) YMF19 PF02326.10 ETO10140.1 - 0.08 13.5 1.0 0.08 13.5 0.7 2.3 2 2 0 2 2 2 0 Plant ATP synthase F0 CH PF00307.26 ETO10141.1 - 4e-06 26.8 2.5 9.6e-06 25.6 0.1 2.7 2 0 0 2 2 2 1 Calponin homology (CH) domain DivIC PF04977.10 ETO10141.1 - 0.0033 16.8 3.8 0.0033 16.8 2.7 7.6 6 2 1 8 8 7 1 Septum formation initiator TSC22 PF01166.13 ETO10141.1 - 0.044 13.7 0.8 0.044 13.7 0.6 5.8 5 2 2 7 7 7 0 TSC-22/dip/bun family Ribosomal_S9 PF00380.14 ETO10141.1 - 0.36 11.0 4.2 4.4 7.5 1.3 2.9 2 0 0 2 2 2 0 Ribosomal protein S9/S16 Surfac_D-trimer PF09006.6 ETO10141.1 - 0.41 10.4 6.1 14 5.5 0.0 4.4 4 0 0 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation Filament PF00038.16 ETO10141.1 - 0.67 9.3 59.1 1.7 8.0 3.6 3.0 1 1 1 2 2 2 0 Intermediate filament protein Reo_sigmaC PF04582.7 ETO10141.1 - 1.3 8.0 6.9 2 7.5 1.4 2.1 1 1 0 1 1 1 0 Reovirus sigma C capsid protein CobU PF02283.11 ETO10141.1 - 2.1 7.7 8.0 2.7 7.3 0.0 3.1 2 1 1 3 3 3 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Baculo_PEP_C PF04513.7 ETO10141.1 - 2.6 7.8 13.9 0.33 10.7 0.6 3.5 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.3 ETO10141.1 - 5.7 4.1 55.8 0.65 7.2 23.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.4 ETO10141.1 - 5.8 6.7 58.4 0.035 13.9 20.2 3.9 1 1 2 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mnd1 PF03962.10 ETO10141.1 - 7.3 6.2 54.3 3.1 7.4 5.8 4.7 1 1 2 3 3 3 0 Mnd1 family Lung_7-TM_R PF06814.8 ETO10142.1 - 5.1e-59 199.6 24.2 1e-58 198.6 16.8 1.5 1 1 0 1 1 1 1 Lung seven transmembrane receptor TRAP_alpha PF03896.11 ETO10142.1 - 0.00038 19.5 1.2 0.00059 18.9 0.9 1.2 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF1510 PF07423.6 ETO10142.1 - 0.0044 16.4 0.1 0.0067 15.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) RELT PF12606.3 ETO10142.1 - 1.7 7.8 0.0 1.7 7.8 0.0 3.9 3 1 0 3 3 3 0 Tumour necrosis factor receptor superfamily member 19 TPR_11 PF13414.1 ETO10143.1 - 0.0022 17.5 2.7 0.0047 16.5 1.9 1.5 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 ETO10143.1 - 0.0092 15.8 2.6 0.024 14.5 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO10143.1 - 0.025 14.1 1.7 0.046 13.3 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat GvpL_GvpF PF06386.6 ETO10143.1 - 0.53 9.8 10.2 0.84 9.1 7.1 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF TPR_8 PF13181.1 ETO10143.1 - 0.9 9.4 3.5 2.2 8.2 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Exonuc_VII_L PF02601.10 ETO10143.1 - 1.7 7.7 10.1 1.7 7.7 7.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spore_coat_CotO PF14153.1 ETO10143.1 - 2.4 7.5 19.0 3.4 7.0 13.2 1.3 1 0 0 1 1 1 0 Spore coat protein CotO TFIIA PF03153.8 ETO10143.1 - 5.3 6.8 20.9 6.5 6.5 14.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAS PF00989.19 ETO10143.1 - 5.3 6.8 6.5 2.7 7.7 2.7 1.9 2 1 0 2 2 2 0 PAS fold TPR_11 PF13414.1 ETO10144.1 - 1.4e-22 79.1 29.2 7.9e-08 31.8 0.0 7.2 4 3 3 7 7 7 6 TPR repeat TPR_2 PF07719.12 ETO10144.1 - 4e-14 51.3 28.9 0.013 15.3 0.0 9.5 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_12 PF13424.1 ETO10144.1 - 1.5e-13 50.4 20.5 0.0022 17.8 1.3 6.6 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_19 PF14559.1 ETO10144.1 - 4.5e-13 49.3 14.7 0.00024 21.3 0.1 7.1 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO10144.1 - 1e-11 45.1 4.4 1.2e-05 25.8 0.0 6.1 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO10144.1 - 1.5e-11 43.8 0.9 0.027 15.0 0.0 6.7 5 1 2 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO10144.1 - 5.3e-10 38.6 16.6 0.028 14.5 0.0 7.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO10144.1 - 5.3e-10 38.4 21.6 0.044 13.4 0.1 7.8 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO10144.1 - 9e-10 37.6 14.1 0.083 12.7 0.0 6.9 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO10144.1 - 5.3e-06 26.1 7.7 0.013 15.3 0.0 6.0 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO10144.1 - 5.8e-06 25.7 7.7 4.1 7.4 0.1 6.9 6 1 0 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO10144.1 - 0.00038 20.5 28.2 0.00081 19.4 0.1 5.0 3 2 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 ETO10144.1 - 0.00061 19.8 2.7 0.021 14.9 0.0 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETO10144.1 - 0.0095 15.7 2.0 0.34 10.7 0.0 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO10144.1 - 0.033 14.6 8.5 9.1 6.9 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF4557 PF15101.1 ETO10144.1 - 0.25 11.1 8.5 0.54 10.0 5.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) BAF1_ABF1 PF04684.8 ETO10144.1 - 6.8 5.4 15.2 14 4.4 0.0 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor RhoGEF PF00621.15 ETO10145.1 - 5.8e-13 49.1 3.3 5.8e-13 49.1 2.3 2.3 1 1 1 2 2 2 1 RhoGEF domain Asp_protease PF09668.5 ETO10149.1 - 8.2e-21 73.8 0.7 2.3e-09 36.8 0.1 2.3 1 1 1 2 2 2 2 Aspartyl protease UBA PF00627.26 ETO10149.1 - 0.0014 18.3 0.1 0.0025 17.6 0.1 1.4 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 ETO10149.1 - 0.011 15.1 0.0 0.032 13.7 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain Med3 PF11593.3 ETO10149.1 - 0.13 11.4 19.5 0.17 11.0 13.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TFIIA PF03153.8 ETO10149.1 - 0.54 10.0 8.5 0.66 9.8 5.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOBP PF15279.1 ETO10149.1 - 0.87 9.9 10.3 1.2 9.4 7.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4551 PF15087.1 ETO10149.1 - 1.7 6.9 8.1 2.3 6.4 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Plasmodium_Vir PF05795.6 ETO10149.1 - 2.3 7.3 6.6 3.9 6.5 4.6 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DDHD PF02862.12 ETO10149.1 - 2.6 7.8 9.2 3.9 7.2 6.4 1.3 1 0 0 1 1 1 0 DDHD domain Macoilin PF09726.4 ETO10149.1 - 3.8 5.6 13.8 4.8 5.3 9.6 1.1 1 0 0 1 1 1 0 Transmembrane protein PIH1 PF08190.7 ETO10149.1 - 4.3 6.6 9.4 6.1 6.1 6.5 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 DUF966 PF06136.8 ETO10149.1 - 4.8 6.5 12.5 6 6.1 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) TTL PF03133.10 ETO10150.1 - 3.1e-30 105.1 1.1 4.7e-30 104.5 0.7 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family TTL PF03133.10 ETO10151.1 - 1.2e-21 76.9 0.0 2.3e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family DUSP PF06337.7 ETO10152.1 - 3.8e-19 68.9 0.1 3.8e-19 68.9 0.1 3.1 3 0 0 3 3 3 1 DUSP domain Casc1 PF12366.3 ETO10152.1 - 0.0053 16.2 6.0 0.63 9.4 0.6 2.4 2 0 0 2 2 2 2 Cancer susceptibility candidate 1 Utp21 PF04192.7 ETO10152.1 - 0.016 14.3 2.8 0.056 12.5 1.9 1.9 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain AAA_23 PF13476.1 ETO10152.1 - 0.02 15.2 3.3 0.02 15.2 2.3 2.3 3 0 0 3 3 3 0 AAA domain Kei1 PF08552.6 ETO10152.1 - 0.029 14.0 0.2 0.029 14.0 0.1 3.1 3 1 0 3 3 2 0 Inositolphosphorylceramide synthase subunit Kei1 DUF4199 PF13858.1 ETO10152.1 - 0.12 12.2 0.2 0.12 12.2 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Ctr PF04145.10 ETO10152.1 - 0.15 12.1 5.8 0.27 11.3 0.0 3.0 2 1 0 2 2 2 0 Ctr copper transporter family Hep_59 PF07052.6 ETO10152.1 - 0.21 11.9 15.7 0.042 14.1 1.2 2.8 2 1 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 Mucin PF01456.12 ETO10152.1 - 0.49 10.1 49.3 11 5.7 6.5 4.0 4 0 0 4 4 4 0 Mucin-like glycoprotein Patched PF02460.13 ETO10152.1 - 0.56 8.0 4.5 0.076 10.9 0.2 1.6 2 0 0 2 2 2 0 Patched family DUF4094 PF13334.1 ETO10152.1 - 2.8 8.3 7.1 0.18 12.2 0.3 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF4094) Prp18 PF02840.10 ETO10152.1 - 3 7.6 7.6 0.75 9.6 1.2 2.7 3 0 0 3 3 3 0 Prp18 domain Mob1_phocein PF03637.12 ETO10153.1 - 1e-70 236.9 0.1 1.3e-70 236.6 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family RAP1 PF07218.6 ETO10153.1 - 0.4 8.7 3.3 0.62 8.0 2.3 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SR-25 PF10500.4 ETO10153.1 - 0.84 9.0 7.1 1.2 8.5 4.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TRAPPC-Trs85 PF12739.2 ETO10155.1 - 8.7e-39 133.3 0.2 1.1e-38 132.9 0.2 1.1 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Exo_endo_phos PF03372.18 ETO10157.1 - 2.3e-07 31.0 0.0 2.9e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Tropomyosin PF00261.15 ETO10157.1 - 0.068 12.2 1.6 0.11 11.6 1.1 1.2 1 0 0 1 1 1 0 Tropomyosin VHP PF02209.14 ETO10157.1 - 1.3 8.7 8.8 0.15 11.7 1.3 2.5 2 0 0 2 2 2 0 Villin headpiece domain RhoGAP PF00620.22 ETO10158.1 - 1.6e-15 57.0 0.0 2.8e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.18 ETO10158.1 - 0.0037 17.2 0.0 0.0057 16.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TPR_2 PF07719.12 ETO10160.1 - 0.00022 20.9 0.1 1.1 9.3 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO10160.1 - 0.0018 18.3 1.3 0.0065 16.5 0.0 2.4 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 ETO10160.1 - 0.0044 16.9 0.3 2.7 7.9 0.0 2.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO10160.1 - 0.0073 16.0 0.1 2.5 8.0 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF1034 PF06280.7 ETO10160.1 - 0.019 15.3 1.6 0.33 11.3 1.5 2.1 2 0 0 2 2 2 0 Fn3-like domain (DUF1034) TPR_7 PF13176.1 ETO10160.1 - 0.2 11.5 1.0 0.71 9.8 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat RGS PF00615.14 ETO10161.1 - 0.0027 17.8 0.0 0.0097 16.0 0.0 2.1 2 1 0 2 2 2 1 Regulator of G protein signaling domain Alpha-amylase_C PF02806.13 ETO10162.1 - 0.12 12.5 0.7 0.19 11.8 0.5 1.3 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain TPT PF03151.11 ETO10163.1 - 8.3e-14 51.4 9.8 1.2e-13 50.9 6.8 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.6 ETO10163.1 - 1.6e-05 23.9 8.3 2.1e-05 23.5 5.8 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 ETO10163.1 - 0.91 9.5 12.4 0.22 11.5 6.3 1.6 1 1 0 1 1 1 0 EamA-like transporter family EmrE PF13536.1 ETO10163.1 - 1.3 9.2 12.0 0.19 11.9 3.5 2.1 2 0 0 2 2 2 0 Multidrug resistance efflux transporter Sulfotransfer_3 PF13469.1 ETO10164.1 - 0.00038 21.4 0.0 0.00083 20.3 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase family ETRAMP PF09716.5 ETO10164.1 - 0.0012 18.7 0.1 0.0042 16.9 0.0 1.9 2 0 0 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) DUF1509 PF07420.6 ETO10165.1 - 0.12 11.6 5.0 0.14 11.4 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Big_1 PF02369.11 ETO10165.1 - 0.15 11.9 1.8 0.15 11.9 0.3 1.7 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) PI3_PI4_kinase PF00454.22 ETO10166.1 - 2.5e-07 30.3 0.0 3.6e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Kinesin PF00225.18 ETO10167.1 - 3.6e-60 203.4 1.2 1.4e-58 198.1 0.8 2.3 1 1 0 1 1 1 1 Kinesin motor domain Utp21 PF04192.7 ETO10168.1 - 0.0067 15.5 1.2 0.0077 15.3 0.8 1.0 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain Drf_FH1 PF06346.7 ETO10169.1 - 0.0018 17.8 31.7 0.0018 17.8 22.0 1.7 2 0 0 2 2 2 1 Formin Homology Region 1 EF-hand_8 PF13833.1 ETO10169.1 - 0.0046 16.5 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 ETO10169.1 - 0.039 14.0 0.1 0.13 12.4 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain pair DrsE_2 PF13686.1 ETO10169.1 - 0.07 12.9 1.6 0.86 9.3 0.1 2.5 2 0 0 2 2 2 0 DsrE/DsrF/DrsH-like family WD40 PF00400.27 ETO10171.1 - 6.6e-08 32.1 0.1 0.00014 21.6 0.0 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat CNH PF00780.17 ETO10171.1 - 0.00099 18.5 1.0 0.43 9.9 0.1 2.3 2 0 0 2 2 2 2 CNH domain DUF2881 PF11087.3 ETO10171.1 - 0.8 9.2 6.9 0.71 9.4 1.8 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2881) FLO_LFY PF01698.11 ETO10171.1 - 9.1 5.0 10.9 15 4.3 7.6 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Ribosomal_S9 PF00380.14 ETO10172.1 - 3.6e-13 49.8 1.9 8.1e-13 48.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S9/S16 WD40 PF00400.27 ETO10173.1 - 1.8e-08 33.9 7.2 0.00043 20.0 0.1 3.8 3 1 0 3 3 3 3 WD domain, G-beta repeat ATP_bind_4 PF01902.12 ETO10173.1 - 0.028 13.7 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 ATP-binding region tRNA_int_endo PF01974.12 ETO10174.1 - 2.1e-06 27.4 0.3 3.7e-05 23.4 0.2 2.2 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Rapsyn_N PF10579.4 ETO10174.1 - 0.049 13.4 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region CxxCxxCC PF03692.10 ETO10174.1 - 2 8.9 7.0 0.49 10.9 1.2 2.3 3 0 0 3 3 3 0 Putative zinc- or iron-chelating domain Helicase_C PF00271.26 ETO10175.1 - 2.2e-07 30.6 0.0 7.6e-07 28.9 0.0 1.9 2 1 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 ETO10176.1 - 4e-07 29.6 6.5 4e-07 29.6 4.5 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO10176.1 - 4.8e-07 29.3 9.0 1.2e-06 28.0 6.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 ETO10176.1 - 7.4e-07 28.9 7.3 1.6e-06 27.8 5.0 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.1 ETO10176.1 - 1.2e-06 27.8 3.7 1.2e-06 27.8 2.6 1.7 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.1 ETO10176.1 - 3.4e-06 26.9 8.9 1.1e-05 25.3 6.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO10176.1 - 0.00012 21.6 8.9 0.00031 20.3 6.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SNF2_N PF00176.18 ETO10176.1 - 0.00026 19.8 0.4 0.0045 15.8 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-rbx1 PF12678.2 ETO10176.1 - 0.00086 19.3 3.4 0.0024 17.9 2.3 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 ETO10176.1 - 0.0025 17.6 1.6 0.0046 16.7 1.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 ETO10176.1 - 0.0088 15.9 8.8 0.02 14.7 6.1 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 ETO10176.1 - 0.0097 15.6 4.6 0.03 14.0 3.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-UDP PF14569.1 ETO10176.1 - 0.014 15.1 1.9 0.11 12.3 1.3 2.4 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-RING_6 PF14835.1 ETO10176.1 - 0.02 14.6 3.6 0.047 13.4 2.5 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-MIZ PF02891.15 ETO10176.1 - 0.034 13.6 3.2 0.075 12.5 2.2 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_4 PF14570.1 ETO10176.1 - 0.084 12.4 6.8 0.23 11.0 4.7 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain TF_Zn_Ribbon PF08271.7 ETO10176.1 - 0.34 10.2 5.7 0.083 12.2 0.5 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding Nop14 PF04147.7 ETO10176.1 - 0.35 8.7 14.2 0.52 8.1 9.8 1.1 1 0 0 1 1 1 0 Nop14-like family zf-trcl PF13451.1 ETO10176.1 - 0.59 9.8 6.5 5.4 6.7 0.0 3.6 3 0 0 3 3 3 0 Probable zinc-binding domain Myc_N PF01056.13 ETO10176.1 - 0.66 9.0 11.2 1.5 7.8 7.8 1.5 1 1 0 1 1 1 0 Myc amino-terminal region Tom37_C PF11801.3 ETO10176.1 - 0.69 9.7 6.3 1.2 8.9 4.4 1.4 1 0 0 1 1 1 0 Tom37 C-terminal domain RNA_polI_A34 PF08208.6 ETO10176.1 - 0.93 9.1 12.0 1.4 8.5 8.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CDC45 PF02724.9 ETO10176.1 - 1.4 6.8 11.3 1.8 6.4 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein YqfQ PF14181.1 ETO10176.1 - 2.3 8.2 11.8 5.1 7.1 8.2 1.5 1 0 0 1 1 1 0 YqfQ-like protein SNF2_N PF00176.18 ETO10177.1 - 2.7e-59 200.3 0.0 3.3e-59 200.1 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 ETO10177.1 - 0.00018 21.0 0.0 0.0003 20.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4227 PF14004.1 ETO10181.1 - 6.5 6.6 6.4 8.7 6.2 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) ubiquitin PF00240.18 ETO10182.1 - 0.0021 17.3 0.1 0.0054 16.0 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family Syndecan PF01034.15 ETO10182.1 - 0.028 14.0 0.1 0.11 12.1 0.1 2.0 1 0 0 1 1 1 0 Syndecan domain DUF740 PF05340.7 ETO10182.1 - 0.24 9.7 7.4 0.35 9.1 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF740) BSMAP PF12280.3 ETO10182.1 - 0.33 10.8 3.5 0.71 9.7 2.5 1.5 1 0 0 1 1 1 0 Brain specific membrane anchored protein DUF3866 PF12982.2 ETO10183.1 - 0.016 14.1 0.5 0.021 13.7 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3866) RFPL3_antisense PF10489.4 ETO10183.1 - 0.018 14.7 0.8 0.052 13.3 0.5 1.7 1 0 0 1 1 1 0 Ret finger protein-like 3 antisense UPF0004 PF00919.15 ETO10183.1 - 0.047 13.5 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein family UPF0004 DUF3011 PF11218.3 ETO10183.1 - 0.051 13.3 0.9 0.093 12.4 0.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3011) DnaJ PF00226.26 ETO10184.1 - 6.8e-21 73.7 4.2 1.2e-20 72.9 2.9 1.5 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.8 ETO10184.1 - 5.3e-06 25.8 3.6 1.3e-05 24.5 2.5 1.7 1 0 0 1 1 1 1 CSL zinc finger Cathelicidins PF00666.12 ETO10184.1 - 0.13 12.4 2.9 0.2 11.8 0.2 2.2 2 0 0 2 2 2 0 Cathelicidin RabGAP-TBC PF00566.13 ETO10185.1 - 5.6e-35 120.7 2.0 1.3e-31 109.7 0.1 3.0 2 1 1 3 3 3 2 Rab-GTPase-TBC domain H_PPase PF03030.11 ETO10186.1 - 1.4e-133 446.5 7.6 1.7e-133 446.3 5.3 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase TatD_DNase PF01026.16 ETO10187.1 - 1.6e-22 79.9 0.0 5.4e-22 78.2 0.0 1.8 2 0 0 2 2 2 1 TatD related DNase WBP-1 PF11669.3 ETO10187.1 - 0.16 12.0 2.4 0.93 9.6 1.7 2.3 1 1 0 1 1 1 0 WW domain-binding protein 1 UCH PF00443.24 ETO10188.1 - 1e-18 67.4 0.9 1.4e-18 67.0 0.6 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO10188.1 - 4.9e-10 39.3 1.7 8.7e-08 31.9 1.2 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3024 PF11225.3 ETO10188.1 - 0.06 13.2 0.3 4.4 7.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3024) CoA_transf_3 PF02515.12 ETO10189.1 - 7.9e-35 119.8 0.0 1.5e-33 115.6 0.0 2.1 1 1 0 1 1 1 1 CoA-transferase family III Hid1 PF12722.2 ETO10192.1 - 5.7 4.4 27.1 6.4 4.3 18.8 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Methyltransf_32 PF13679.1 ETO10193.1 - 2.5e-05 23.9 5.0 0.00083 19.0 3.5 2.5 1 1 0 1 1 1 1 Methyltransferase domain IBR PF01485.16 ETO10194.1 - 0.027 14.3 0.5 0.046 13.5 0.4 1.3 1 0 0 1 1 1 0 IBR domain zf-RING_5 PF14634.1 ETO10194.1 - 0.06 13.0 1.8 0.097 12.4 1.2 1.3 1 0 0 1 1 1 0 zinc-RING finger domain DUF2457 PF10446.4 ETO10194.1 - 0.078 11.7 10.4 0.096 11.4 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sigma70_ner PF04546.8 ETO10194.1 - 0.093 12.3 4.1 0.13 11.8 2.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 ETO10194.1 - 0.34 10.4 7.8 0.62 9.5 5.4 1.4 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 ETO10194.1 - 0.41 10.4 6.5 0.61 9.8 4.5 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.5 ETO10194.1 - 1.6 9.0 11.2 2.8 8.2 7.8 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 ETO10194.1 - 3.5 8.0 9.4 8.6 6.7 6.5 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myotub-related PF06602.9 ETO10195.1 - 2.3e-101 339.1 5.0 4e-87 292.2 0.1 2.0 1 1 1 2 2 2 2 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 ETO10195.1 - 2.4e-05 23.7 0.4 4.9e-05 22.7 0.1 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.15 ETO10195.1 - 6.3e-05 22.5 0.3 0.00012 21.6 0.2 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 ETO10195.1 - 0.00024 21.4 0.0 0.0004 20.6 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 ETO10195.1 - 0.0017 17.7 0.1 0.0034 16.7 0.1 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family ArfGap PF01412.13 ETO10196.1 - 0.59 9.9 5.8 0.082 12.7 0.5 2.2 2 1 0 2 2 2 0 Putative GTPase activating protein for Arf PARG_cat PF05028.9 ETO10197.1 - 5.5e-68 229.7 11.7 2.4e-41 142.1 0.1 3.6 2 1 0 3 3 3 3 Poly (ADP-ribose) glycohydrolase (PARG) Secretin_N_2 PF07655.8 ETO10197.1 - 1.7 9.1 11.8 3.5 8.0 8.2 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain Kelch_1 PF01344.20 ETO10200.1 - 0.24 10.9 0.9 0.5 9.9 0.2 1.9 2 0 0 2 2 2 0 Kelch motif DUF2853 PF11015.3 ETO10201.1 - 0.00038 20.8 0.8 0.00087 19.7 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2853) DUF3186 PF11382.3 ETO10201.1 - 0.017 14.2 0.6 0.027 13.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3186) GCIP PF13324.1 ETO10201.1 - 0.02 14.1 0.1 0.042 13.0 0.1 1.7 1 1 0 1 1 1 0 Grap2 and cyclin-D-interacting Cyt-b5 PF00173.23 ETO10202.1 - 5.3e-17 61.3 0.1 1.4e-16 60.0 0.1 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Utp14 PF04615.8 ETO10202.1 - 7.9 4.5 24.5 12 3.8 17.0 1.3 1 0 0 1 1 1 0 Utp14 protein ABC_membrane PF00664.18 ETO10203.1 - 1.5e-36 126.2 8.9 2e-36 125.8 6.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF3592 PF12158.3 ETO10204.1 - 1.4 8.6 4.6 4.4 7.0 3.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3592) DUF4400 PF14348.1 ETO10205.1 - 1.1 8.5 3.1 0.45 9.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) Vfa1 PF08432.5 ETO10206.1 - 0.043 13.8 25.4 0.033 14.2 4.2 3.2 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 Zip PF02535.17 ETO10206.1 - 0.15 11.0 4.0 5.1 6.0 0.1 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter Presenilin PF01080.12 ETO10206.1 - 4 6.1 9.0 0.19 10.4 0.5 2.1 2 0 0 2 2 2 0 Presenilin TPR_12 PF13424.1 ETO10208.1 - 6.2e-52 173.4 2.9 4.9e-21 74.4 0.1 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO10208.1 - 3.1e-20 71.6 2.4 5.2e-10 38.8 0.0 2.1 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETO10208.1 - 3.7e-17 61.1 14.8 1.5e-09 37.0 0.2 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO10208.1 - 2.2e-15 56.0 0.0 3.9e-05 23.4 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO10208.1 - 4.4e-14 51.0 0.9 7.5e-05 22.2 0.0 4.4 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO10208.1 - 1.4e-12 46.5 8.7 4.6e-05 23.0 0.0 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO10208.1 - 2.4e-10 39.4 18.1 5.3e-07 28.9 0.3 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO10208.1 - 1.1e-09 37.6 0.6 0.0015 18.6 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO10208.1 - 0.0021 18.4 0.1 8.2 7.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO10208.1 - 0.0061 16.6 5.8 0.067 13.3 1.8 2.9 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 ETO10208.1 - 0.014 14.6 0.0 12 5.2 0.0 3.3 3 1 0 3 3 3 0 SHNi-TPR Pep3_Vps18 PF05131.9 ETO10208.1 - 0.017 14.5 0.2 2 7.8 0.0 2.6 3 0 0 3 3 3 0 Pep3/Vps18/deep orange family TPR_14 PF13428.1 ETO10208.1 - 0.052 14.1 0.0 3.8 8.3 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETO10208.1 - 0.13 12.9 0.0 23 5.8 0.0 2.7 2 1 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.15 ETO10208.1 - 0.13 12.2 1.5 0.3 11.1 0.1 2.4 3 0 0 3 3 3 0 PPR repeat TPR_3 PF07720.7 ETO10208.1 - 1.3 8.8 9.6 0.85 9.4 1.6 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TFIIE_alpha PF02002.12 ETO10208.1 - 3.7 7.1 5.6 2.2 7.8 0.2 2.3 2 0 0 2 2 2 0 TFIIE alpha subunit SET PF00856.23 ETO10209.1 - 7.5e-26 91.3 0.5 2e-25 89.9 0.4 1.7 1 1 0 1 1 1 1 SET domain Sulfotransfer_3 PF13469.1 ETO10210.1 - 0.00021 22.2 2.1 0.0099 16.8 1.4 2.8 1 1 0 1 1 1 1 Sulfotransferase family Kunitz_legume PF00197.13 ETO10210.1 - 0.07 12.6 0.2 0.07 12.6 0.2 1.6 2 0 0 2 2 2 0 Trypsin and protease inhibitor amfpi-1 PF12190.3 ETO10210.1 - 0.08 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Fungal protease inhibitor LRR19-TM PF15176.1 ETO10211.1 - 0.043 13.5 0.2 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain WTF PF03303.8 ETO10211.1 - 0.063 12.6 0.5 0.14 11.5 0.4 1.5 1 0 0 1 1 1 0 WTF protein DUF3753 PF12575.3 ETO10211.1 - 0.073 12.8 0.6 1.4 8.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) DUF912 PF06024.7 ETO10211.1 - 4 7.5 4.9 2.1 8.4 0.2 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) AIG2_2 PF13772.1 ETO10213.1 - 2.9e-06 27.2 0.0 6.2e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 AIG2-like family AIG2 PF06094.7 ETO10213.1 - 0.11 13.0 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 AIG2-like family G-alpha PF00503.15 ETO10214.1 - 3.2e-76 256.5 24.0 6.2e-63 212.7 10.8 2.6 2 1 0 2 2 2 2 G-protein alpha subunit Arf PF00025.16 ETO10214.1 - 4.3e-09 35.8 3.0 2.1e-06 27.0 0.0 3.0 3 0 0 3 3 3 2 ADP-ribosylation factor family AAA_14 PF13173.1 ETO10214.1 - 0.021 14.7 0.5 1.4 8.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain UPF0542 PF15086.1 ETO10214.1 - 0.028 14.1 2.9 0.075 12.7 2.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 Miro PF08477.8 ETO10214.1 - 0.03 14.8 0.7 5.3 7.5 0.0 3.1 3 0 0 3 3 3 0 Miro-like protein Sugar_tr PF00083.19 ETO10214.1 - 0.071 11.6 0.1 0.071 11.6 0.1 1.8 2 0 0 2 2 2 0 Sugar (and other) transporter SR-25 PF10500.4 ETO10214.1 - 0.46 9.9 11.4 0.74 9.2 7.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Peptidase_S49_N PF08496.5 ETO10214.1 - 1.7 8.4 7.7 3.1 7.5 5.3 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RAB3GAP2_N PF14655.1 ETO10216.1 - 5.7e-27 94.7 0.1 1.3e-19 70.5 0.0 2.3 2 0 0 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus SPRY PF00622.23 ETO10216.1 - 1.8e-05 24.8 0.4 4.9e-05 23.4 0.1 1.8 2 0 0 2 2 2 1 SPRY domain DEP PF00610.16 ETO10217.1 - 2e-32 110.7 2.8 2e-17 62.6 0.3 2.7 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF2188 PF09954.4 ETO10217.1 - 0.075 12.9 1.0 6.1 6.8 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Exo_endo_phos PF03372.18 ETO10218.1 - 1.6e-22 80.6 0.0 2.2e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 ETO10218.1 - 1.8e-05 24.3 0.0 5.8e-05 22.6 0.0 2.0 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Peptidase_C41 PF05417.6 ETO10218.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Hepatitis E cysteine protease 2_5_RNA_ligase2 PF13563.1 ETO10220.1 - 4.4e-30 104.4 0.4 6.6e-30 103.8 0.3 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily DUF488 PF04343.8 ETO10220.1 - 2.7e-13 50.3 1.2 5.4e-12 46.1 0.2 2.8 2 1 0 2 2 2 1 Protein of unknown function, DUF488 FAM86 PF14904.1 ETO10220.1 - 0.012 15.2 0.4 0.029 14.0 0.1 1.7 1 1 0 1 1 1 0 Family of unknown function zf-Di19 PF05605.7 ETO10220.1 - 0.023 14.8 1.5 2.5 8.3 0.1 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Podoplanin PF05808.6 ETO10221.1 - 0.013 15.0 0.5 0.031 13.8 0.0 1.8 2 0 0 2 2 2 0 Podoplanin START PF01852.14 ETO10222.1 - 3.2e-12 46.2 2.1 1.5e-08 34.2 0.0 3.1 3 1 0 3 3 3 2 START domain Pex14_N PF04695.8 ETO10222.1 - 7.4 6.6 11.9 20 5.1 1.3 3.4 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Amidohydro_2 PF04909.9 ETO10223.1 - 9e-25 87.7 0.0 1.1e-24 87.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase COPIIcoated_ERV PF07970.7 ETO10224.1 - 1.4e-46 158.9 0.2 1.9e-46 158.5 0.2 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 ETO10225.1 - 7.1e-21 74.0 0.2 9.3e-21 73.6 0.2 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF1422 PF07226.6 ETO10225.1 - 0.018 14.7 0.4 0.022 14.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) DUF673 PF05054.7 ETO10226.1 - 0.0066 15.0 0.0 0.007 14.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF673) RRM_1 PF00076.17 ETO10227.1 - 0.00065 19.2 0.1 0.064 12.9 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO10227.1 - 0.0046 16.9 0.0 0.13 12.2 0.0 2.6 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) L_protein_N PF15518.1 ETO10227.1 - 0.047 13.0 0.1 0.088 12.1 0.0 1.4 1 0 0 1 1 1 0 L protein N-terminus Ras_bdg_2 PF14847.1 ETO10227.1 - 0.11 12.4 1.9 0.92 9.4 1.3 2.3 1 1 0 1 1 1 0 Ras-binding domain of Byr2 RRM_6 PF14259.1 ETO10228.1 - 4.2e-12 45.8 0.2 6.7e-06 25.9 0.0 4.6 5 1 0 5 5 5 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO10228.1 - 6.2e-10 38.5 0.0 0.0056 16.2 0.0 4.9 6 0 0 6 6 6 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO10228.1 - 0.00012 21.7 1.9 0.033 14.0 0.0 3.6 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Menin PF05053.8 ETO10228.1 - 0.045 11.9 8.2 0.065 11.3 5.7 1.1 1 0 0 1 1 1 0 Menin RR_TM4-6 PF06459.7 ETO10228.1 - 1.8 8.3 12.8 2.8 7.7 8.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop14 PF04147.7 ETO10228.1 - 7.7 4.2 18.9 11 3.7 13.1 1.1 1 0 0 1 1 1 0 Nop14-like family PH PF00169.24 ETO10229.1 - 7.5e-05 22.8 2.2 0.00019 21.5 1.6 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 ETO10229.1 - 0.0034 17.6 0.9 0.0034 17.6 0.6 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain DUF334 PF03904.8 ETO10229.1 - 0.48 9.7 6.7 0.87 8.8 4.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF334) CH PF00307.26 ETO10230.1 - 2.5e-19 69.3 8.1 1.8e-07 31.1 0.0 5.4 4 3 0 4 4 4 3 Calponin homology (CH) domain CAMSAP_CH PF11971.3 ETO10230.1 - 4e-07 29.5 1.9 0.083 12.5 0.1 3.7 3 0 0 3 3 3 2 CAMSAP CH domain Melibiase PF02065.13 ETO10231.1 - 7.4e-20 70.9 0.2 8e-15 54.4 0.0 2.9 3 0 0 3 3 3 2 Melibiase Amidohydro_2 PF04909.9 ETO10232.1 - 2.5e-17 63.3 0.0 3.1e-17 63.0 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase Sigma54_activ_2 PF14532.1 ETO10233.1 - 0.0026 17.7 0.0 0.0049 16.9 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain DUF1510 PF07423.6 ETO10236.1 - 0.082 12.2 2.6 0.1 11.9 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4637 PF15470.1 ETO10236.1 - 0.12 11.9 1.2 0.16 11.5 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF959 PF06121.9 ETO10237.1 - 0.037 13.6 2.3 0.054 13.1 1.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF959) DUF3519 PF12033.3 ETO10237.1 - 4.5 7.5 16.1 0.068 13.3 4.7 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3519) BTB PF00651.26 ETO10238.1 - 0.00082 19.3 0.7 0.0019 18.1 0.1 1.9 2 1 0 2 2 2 1 BTB/POZ domain TRAP_alpha PF03896.11 ETO10239.1 - 0.09 11.7 3.4 0.16 10.9 2.3 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Kei1 PF08552.6 ETO10239.1 - 0.095 12.3 4.8 0.18 11.4 1.4 2.0 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 EIIBC-GUT_N PF03612.9 ETO10239.1 - 0.1 12.2 1.9 0.21 11.1 1.3 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus GOLD_2 PF13897.1 ETO10239.1 - 0.26 11.5 3.1 0.57 10.4 2.2 1.5 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking TraH_2 PF06871.6 ETO10239.1 - 0.63 9.4 3.5 1.1 8.7 2.4 1.3 1 0 0 1 1 1 0 TraH_2 Peptidase_S49_N PF08496.5 ETO10239.1 - 3.8 7.3 7.5 3.3 7.4 3.2 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Ribosomal_60s PF00428.14 ETO10240.1 - 0.036 14.4 0.7 0.75 10.2 0.1 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF479 PF04336.7 ETO10240.1 - 2.1 8.4 9.3 0.71 10.0 1.3 3.3 3 0 0 3 3 3 0 Protein of unknown function, DUF479 PBP1_TM PF14812.1 ETO10241.1 - 0.0032 17.7 7.1 0.0032 17.7 4.9 4.1 4 1 0 4 4 4 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.1 ETO10241.1 - 0.014 15.5 4.9 0.014 15.5 3.4 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 ETO10241.1 - 0.014 14.8 5.5 0.014 14.8 3.8 2.6 2 1 0 2 2 2 0 Nucleoplasmin Nop14 PF04147.7 ETO10241.1 - 9.5 3.9 37.3 0.26 9.1 20.2 2.1 2 0 0 2 2 2 0 Nop14-like family TRAUB PF08164.7 ETO10242.1 - 3.9 7.6 9.4 1 9.4 3.9 1.8 2 0 0 2 2 2 0 Apoptosis-antagonizing transcription factor, C-terminal DUF1688 PF07958.6 ETO10243.1 - 2e-129 431.8 1.6 1.6e-112 376.1 0.1 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF1688) GTP_cyclohydro2 PF00925.15 ETO10243.1 - 1.4e-16 60.1 0.0 2.7e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 GTP cyclohydrolase II GTP_CH_N PF12471.3 ETO10243.1 - 0.0025 17.4 0.0 0.0044 16.6 0.0 1.4 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal DUF2419 PF10343.4 ETO10243.1 - 0.047 12.9 0.0 0.16 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2419) Reo_sigmaC PF04582.7 ETO10244.1 - 0.0052 16.0 16.0 0.062 12.4 2.2 3.1 2 1 0 3 3 3 2 Reovirus sigma C capsid protein Spc7 PF08317.6 ETO10244.1 - 0.015 14.0 46.2 0.043 12.4 11.0 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein Streptin-Immun PF11083.3 ETO10244.1 - 2.6 8.1 24.2 0.35 10.9 1.4 4.1 3 1 2 5 5 5 0 Lantibiotic streptin immunity protein GAS PF13851.1 ETO10244.1 - 5.3 6.1 48.5 0.2 10.8 3.0 3.7 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DivIVA PF05103.8 ETO10244.1 - 5.7 6.9 43.4 0.57 10.2 2.8 3.9 2 2 1 3 3 3 0 DivIVA protein DUF3450 PF11932.3 ETO10244.1 - 8.6 5.5 36.8 3.4 6.8 0.7 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) IncA PF04156.9 ETO10244.1 - 9.8 5.7 52.9 0.74 9.3 4.9 3.9 2 1 0 2 2 2 0 IncA protein DUF4288 PF14119.1 ETO10246.1 - 0.0041 17.2 0.0 0.0058 16.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4288) Trep_dent_lipo PF09710.5 ETO10246.1 - 0.0083 14.8 0.5 0.011 14.4 0.4 1.1 1 0 0 1 1 1 1 Treponema clustered lipoprotein (Trep_dent_lipo) DUF2147 PF09917.4 ETO10246.1 - 0.022 14.9 0.1 0.036 14.3 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2147) Sybindin PF04099.7 ETO10246.1 - 0.031 13.9 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Sybindin-like family TMEM171 PF15471.1 ETO10249.1 - 0.12 11.1 1.0 0.2 10.3 0.7 1.4 1 1 0 1 1 1 0 Transmembrane protein family 171 RDD PF06271.7 ETO10250.1 - 5.7 6.8 7.6 7.8 6.4 5.3 1.2 1 0 0 1 1 1 0 RDD family Pkinase_Tyr PF07714.12 ETO10251.1 - 4.8e-10 38.9 0.0 8.8e-10 38.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 ETO10251.1 - 9.4e-10 38.0 0.3 2e-09 36.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase PF00069.20 ETO10253.1 - 1.6e-12 47.1 0.0 2.9e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO10253.1 - 3e-12 46.1 0.0 5.2e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF912 PF06024.7 ETO10253.1 - 0.15 12.1 2.5 7.5 6.6 0.1 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) WD40 PF00400.27 ETO10255.1 - 6.1e-78 254.1 20.5 5.6e-13 48.2 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO10255.1 - 7.7e-07 27.6 3.9 0.037 12.1 0.1 5.0 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO10255.1 - 1.5e-05 23.4 1.5 0.066 11.4 0.1 3.9 2 1 3 5 5 5 2 Cytochrome D1 heme domain Kelch_4 PF13418.1 ETO10255.1 - 8.7e-05 22.2 0.1 0.0031 17.2 0.0 3.4 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO10255.1 - 0.0002 21.3 6.2 0.2 11.8 0.0 4.4 3 1 1 4 4 4 2 Kelch motif Nbas_N PF15492.1 ETO10255.1 - 0.00048 19.3 2.1 0.081 12.0 0.0 4.1 2 1 3 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Kelch_1 PF01344.20 ETO10255.1 - 0.00081 18.8 3.2 0.56 9.7 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 ETO10255.1 - 0.0024 17.7 1.1 1.1 9.2 0.0 4.1 4 0 0 4 4 4 1 Kelch motif PQQ_2 PF13360.1 ETO10255.1 - 0.0024 17.3 0.1 0.012 15.1 0.1 2.1 1 1 1 2 2 2 1 PQQ-like domain Proteasome_A_N PF10584.4 ETO10255.1 - 0.031 13.5 0.1 16 4.8 0.0 3.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Kelch_3 PF13415.1 ETO10255.1 - 0.069 13.3 0.0 2.3 8.5 0.0 2.7 2 0 0 2 2 2 0 Galactose oxidase, central domain PD40 PF07676.7 ETO10255.1 - 7.6 6.3 11.3 8.9 6.0 0.1 4.7 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat ETF PF01012.16 ETO10257.1 - 2.3e-24 85.9 0.1 3.7e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain eIF2_C PF09173.6 ETO10257.1 - 0.055 13.5 0.2 0.13 12.3 0.1 1.7 1 1 0 1 1 1 0 Initiation factor eIF2 gamma, C terminal Acetyltransf_6 PF13480.1 ETO10258.1 - 0.069 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Cript PF10235.4 ETO10259.1 - 0.29 11.5 8.2 0.053 13.8 2.8 2.0 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT TPR_19 PF14559.1 ETO10260.1 - 1.6e-05 25.1 23.4 0.77 10.1 0.0 8.3 6 3 1 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO10260.1 - 8.3e-05 22.8 8.3 7.1 7.5 0.0 8.9 9 2 1 10 10 10 1 Tetratricopeptide repeat RtcR PF06956.6 ETO10260.1 - 0.008 15.5 0.4 0.064 12.5 0.0 2.3 2 0 0 2 2 2 1 Regulator of RNA terminal phosphate cyclase TPR_16 PF13432.1 ETO10260.1 - 0.72 10.6 8.7 90 3.9 0.0 6.7 8 0 0 8 8 8 0 Tetratricopeptide repeat Metallophos PF00149.23 ETO10261.1 - 6.7e-35 120.3 0.0 8.8e-35 119.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 ETO10261.1 - 0.0022 17.8 0.0 0.0032 17.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain LRRNT_2 PF08263.7 ETO10262.1 - 0.00024 20.9 0.9 0.00055 19.8 0.6 1.7 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_8 PF13855.1 ETO10262.1 - 0.0013 18.4 0.8 0.0013 18.4 0.5 2.4 2 1 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.2 ETO10262.1 - 0.036 13.6 2.4 0.19 11.4 0.7 2.5 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETO10262.1 - 6.5 7.2 9.5 51 4.4 0.0 4.6 4 1 0 4 4 4 0 Leucine Rich Repeat JmjC PF02373.17 ETO10264.1 - 4.1e-06 27.0 1.3 8e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase 7TM-7TMR_HD PF07698.6 ETO10267.1 - 0.21 11.0 2.6 1.7 8.0 0.1 2.1 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase ETRAMP PF09716.5 ETO10267.1 - 0.21 11.5 3.9 0.099 12.6 0.8 1.8 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Cation_ATPase_C PF00689.16 ETO10267.1 - 1.3 8.4 4.5 2 7.8 3.1 1.2 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus ATP-synt_8 PF00895.15 ETO10267.1 - 2.4 8.4 5.1 0.91 9.7 0.2 2.6 3 0 0 3 3 3 0 ATP synthase protein 8 GATase_2 PF00310.16 ETO10268.1 - 0.0048 15.6 0.1 0.006 15.3 0.1 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II HECT PF00632.20 ETO10269.1 - 2.3e-58 197.8 0.1 4.3e-58 196.9 0.1 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Laminin_G_3 PF13385.1 ETO10269.1 - 3.5e-14 53.3 0.0 7e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.19 ETO10269.1 - 0.0092 16.0 0.1 0.023 14.7 0.0 1.6 1 0 0 1 1 1 1 Laminin G domain IF4E PF01652.13 ETO10270.1 - 1.4e-35 122.2 2.8 2.5e-35 121.4 1.9 1.4 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF4562 PF15123.1 ETO10270.1 - 0.034 14.0 0.1 5.4 6.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4562) Meiosis_expr PF15163.1 ETO10271.1 - 0.36 11.2 2.5 0.89 9.9 0.1 2.2 2 0 0 2 2 2 0 Meiosis-expressed RhoGAP PF00620.22 ETO10272.1 - 3.8e-09 36.3 0.1 6e-07 29.1 0.1 3.1 1 1 0 1 1 1 1 RhoGAP domain LRR_6 PF13516.1 ETO10272.1 - 1.4e-06 27.7 12.6 0.2 11.8 0.3 5.4 4 0 0 4 4 4 3 Leucine Rich repeat RabGAP-TBC PF00566.13 ETO10273.1 - 0.0022 17.5 0.3 0.0022 17.5 0.2 1.9 3 0 0 3 3 3 1 Rab-GTPase-TBC domain DUF912 PF06024.7 ETO10273.1 - 0.026 14.5 0.9 0.026 14.5 0.6 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DRY_EERY PF09750.4 ETO10273.1 - 4.1 7.5 9.5 1.4 9.0 2.5 2.3 2 1 0 2 2 2 0 Alternative splicing regulator Vfa1 PF08432.5 ETO10273.1 - 5.6 6.9 21.2 0.65 9.9 8.3 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 RabGAP-TBC PF00566.13 ETO10274.1 - 1.6e-24 86.5 3.9 2.3e-24 86.0 2.7 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain TMEM238 PF15125.1 ETO10274.1 - 0.11 12.4 0.8 0.61 10.0 0.1 2.5 3 0 0 3 3 3 0 TMEM238 protein family HhH-GPD PF00730.20 ETO10276.1 - 2.1e-05 24.7 0.0 6.2e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein CDC27 PF09507.5 ETO10276.1 - 0.1 11.8 11.8 0.14 11.3 8.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Peptidase_A21 PF03566.8 ETO10276.1 - 0.14 10.2 1.8 0.18 9.8 1.2 1.1 1 0 0 1 1 1 0 Peptidase family A21 SPT6_acidic PF14632.1 ETO10276.1 - 3.2 7.9 13.7 0.21 11.7 5.8 1.8 2 0 0 2 2 2 0 Acidic N-terminal SPT6 NST1 PF13945.1 ETO10276.1 - 3.4 7.7 12.7 2.5 8.1 7.4 1.8 1 1 0 1 1 1 0 Salt tolerance down-regulator Aldedh PF00171.17 ETO10277.1 - 2.8e-141 471.0 0.1 3.9e-140 467.2 0.1 1.9 1 1 0 1 1 1 1 Aldehyde dehydrogenase family DUF4124 PF13511.1 ETO10277.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4124) DUF1882 PF08966.6 ETO10279.1 - 0.026 14.4 1.3 0.067 13.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1882) DOMON PF03351.12 ETO10280.1 - 3.3e-06 27.0 1.4 6.2e-06 26.1 0.8 1.6 1 1 0 1 1 1 1 DOMON domain CSD PF00313.17 ETO10281.1 - 0.00092 18.9 0.1 1.2 8.9 0.0 2.4 2 0 0 2 2 2 2 'Cold-shock' DNA-binding domain Daxx PF03344.10 ETO10282.1 - 0.002 16.6 21.1 0.0025 16.4 14.7 1.1 1 0 0 1 1 1 1 Daxx Family CDC45 PF02724.9 ETO10282.1 - 0.0024 15.9 9.1 0.0027 15.8 6.3 1.3 1 0 0 1 1 1 1 CDC45-like protein MIP-T3 PF10243.4 ETO10282.1 - 0.0043 15.5 17.5 0.0039 15.7 12.1 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Dynamin_N PF00350.18 ETO10282.1 - 0.041 13.6 0.3 0.074 12.8 0.2 1.5 1 0 0 1 1 1 0 Dynamin family Serinc PF03348.10 ETO10282.1 - 0.1 11.3 0.2 0.13 10.9 0.1 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) VID27 PF08553.5 ETO10282.1 - 0.1 10.8 12.9 0.12 10.5 8.9 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein RRN3 PF05327.6 ETO10282.1 - 0.65 8.0 9.2 0.86 7.6 6.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2722 PF10846.3 ETO10282.1 - 1.5 7.7 12.9 2 7.3 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF4637 PF15470.1 ETO10282.1 - 3.6 7.1 12.5 6.7 6.2 8.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Paf1 PF03985.8 ETO10282.1 - 5.3 5.6 21.8 7.6 5.1 15.1 1.3 1 0 0 1 1 1 0 Paf1 CobT PF06213.7 ETO10282.1 - 6.6 5.7 21.4 11 5.0 14.8 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RR_TM4-6 PF06459.7 ETO10282.1 - 9.8 5.9 19.0 19 5.0 13.2 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3819 PF12842.2 ETO10283.1 - 0.0014 18.2 0.8 0.088 12.4 0.7 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3819) DUF3636 PF12331.3 ETO10284.1 - 0.11 12.0 0.1 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3636) Metallothio_2 PF01439.13 ETO10286.1 - 4.5 7.8 11.0 10 6.7 7.2 2.0 1 1 0 1 1 1 0 Metallothionein zf-TRAF PF02176.13 ETO10287.1 - 1.8e-07 31.4 4.7 1.8e-07 31.4 3.2 2.9 2 1 1 3 3 3 1 TRAF-type zinc finger Cas_GSU0054 PF09609.5 ETO10287.1 - 0.1 11.3 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) zf-C3HC4_2 PF13923.1 ETO10287.1 - 5 7.2 15.4 0.45 10.5 5.0 3.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) AIG2 PF06094.7 ETO10288.1 - 1.2e-14 54.5 0.0 2.2e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family AIG2_2 PF13772.1 ETO10288.1 - 2.7e-06 27.3 0.2 7.1e-06 26.0 0.2 1.7 1 0 0 1 1 1 1 AIG2-like family TrbC PF04956.8 ETO10288.1 - 0.045 13.7 0.1 0.072 13.1 0.1 1.2 1 0 0 1 1 1 0 TrbC/VIRB2 family DUF605 PF04652.11 ETO10289.1 - 5e-22 78.8 14.6 9.5e-22 77.9 10.1 1.4 1 1 0 1 1 1 1 Vta1 like Snf7 PF03357.16 ETO10289.1 - 0.038 13.3 2.2 2.8 7.2 0.2 2.1 2 0 0 2 2 2 0 Snf7 Nop14 PF04147.7 ETO10289.1 - 0.63 7.8 7.8 0.68 7.7 5.4 1.1 1 0 0 1 1 1 0 Nop14-like family PTB PF08416.8 ETO10290.1 - 0.033 14.0 0.6 0.67 9.8 0.1 2.3 2 0 0 2 2 2 0 Phosphotyrosine-binding domain Nucleoplasmin PF03066.10 ETO10290.1 - 0.058 12.9 7.1 0.08 12.4 1.7 2.4 2 0 0 2 2 2 0 Nucleoplasmin Hom_end_hint PF05203.11 ETO10290.1 - 0.38 10.4 4.5 0.22 11.2 1.0 2.0 2 0 0 2 2 2 0 Hom_end-associated Hint DUF4484 PF14831.1 ETO10290.1 - 0.54 10.3 8.3 1.1 9.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) Merozoite_SPAM PF07133.6 ETO10290.1 - 0.74 9.6 23.0 0.14 12.0 11.1 2.1 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) GAGA_bind PF06217.7 ETO10290.1 - 1.4 8.8 6.0 1.1 9.1 2.7 1.8 2 0 0 2 2 2 0 GAGA binding protein-like family Vfa1 PF08432.5 ETO10290.1 - 2.4 8.1 13.5 0.43 10.5 5.1 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 FAM176 PF14851.1 ETO10290.1 - 3.2 7.4 9.5 9.1 5.9 4.0 2.3 2 0 0 2 2 2 0 FAM176 family PBP1_TM PF14812.1 ETO10290.1 - 3.9 7.8 16.4 6.7 7.0 1.2 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SDA1 PF05285.7 ETO10290.1 - 8.9 5.4 19.6 2.3 7.4 9.9 2.0 2 0 0 2 2 2 0 SDA1 RRM_1 PF00076.17 ETO10291.1 - 5.4e-08 32.3 0.1 7.8e-06 25.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO10291.1 - 6.6e-07 29.2 0.0 6.1e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-UBR PF02207.15 ETO10292.1 - 1.3e-16 60.0 9.6 2.5e-16 59.1 6.7 1.5 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) KIF1B PF12423.3 ETO10293.1 - 0.053 13.5 0.0 0.34 10.9 0.0 2.4 2 0 0 2 2 2 0 Kinesin protein 1B BUD22 PF09073.5 ETO10293.1 - 2.7 6.9 17.0 5.1 6.0 11.8 1.4 1 0 0 1 1 1 0 BUD22 HTH_Tnp_ISL3 PF13542.1 ETO10294.1 - 0.087 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 NIF PF03031.13 ETO10296.1 - 1.1e-34 119.4 2.4 1.5e-32 112.4 1.6 2.3 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase SelB-wing_3 PF09107.6 ETO10296.1 - 0.079 12.3 0.0 0.52 9.7 0.1 2.1 2 0 0 2 2 2 0 Elongation factor SelB, winged helix XK-related PF09815.4 ETO10297.1 - 4.1e-08 32.6 15.9 4.1e-08 32.6 11.1 2.2 1 1 0 1 1 1 1 XK-related protein HlyC PF02794.11 ETO10298.1 - 0.012 15.2 0.0 0.029 13.9 0.0 1.6 1 0 0 1 1 1 0 RTX toxin acyltransferase family ESCRT-II PF05871.7 ETO10298.1 - 0.14 12.0 3.4 0.34 10.8 1.1 2.4 2 0 0 2 2 2 0 ESCRT-II complex subunit MutS_I PF01624.15 ETO10299.1 - 1.8e-05 24.7 0.7 3.4e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 MutS domain I Apolipoprotein PF01442.13 ETO10300.1 - 0.015 14.8 8.5 0.031 13.7 5.9 1.5 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain EzrA PF06160.7 ETO10300.1 - 0.016 13.4 11.3 0.023 12.9 7.8 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA ALMT PF11744.3 ETO10300.1 - 0.059 12.0 5.5 0.089 11.4 3.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter IncA PF04156.9 ETO10300.1 - 0.16 11.5 11.1 0.26 10.8 7.7 1.3 1 0 0 1 1 1 0 IncA protein DUF948 PF06103.6 ETO10300.1 - 0.27 11.1 5.7 0.95 9.3 1.4 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) COG2 PF06148.6 ETO10300.1 - 0.46 10.3 9.5 6.8 6.5 2.3 2.8 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Mitofilin PF09731.4 ETO10300.1 - 0.66 8.5 12.6 0.98 7.9 8.7 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Vps51 PF08700.6 ETO10300.1 - 0.67 9.8 8.7 26 4.7 0.0 3.9 2 1 1 3 3 3 0 Vps51/Vps67 COG5 PF10392.4 ETO10300.1 - 1.3 8.9 6.5 3.1 7.7 4.5 1.7 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF1664 PF07889.7 ETO10300.1 - 2 8.2 9.1 12 5.6 3.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Kinetocho_Slk19 PF12709.2 ETO10300.1 - 2.3 8.3 14.4 0.38 10.8 2.3 2.6 1 1 1 2 2 2 0 Central kinetochore-associated vATP-synt_E PF01991.13 ETO10300.1 - 2.5 7.3 13.6 2.7 7.2 7.6 2.0 1 1 1 2 2 2 0 ATP synthase (E/31 kDa) subunit DUF1640 PF07798.6 ETO10300.1 - 3.8 7.5 12.1 6.3 6.8 5.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) TPR_MLP1_2 PF07926.7 ETO10300.1 - 4.8 6.9 18.9 4.2 7.1 8.1 2.4 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF972 PF06156.8 ETO10300.1 - 5 7.5 12.8 20 5.5 7.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Kelch_6 PF13964.1 ETO10301.1 - 4.9e-09 35.9 2.0 0.0011 19.0 0.0 4.6 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO10301.1 - 2e-06 27.2 1.0 0.00031 20.2 0.0 3.5 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 ETO10301.1 - 0.00011 21.8 2.1 0.0044 16.7 0.0 4.0 5 0 0 5 5 5 1 Kelch motif Secretin_N_2 PF07655.8 ETO10302.1 - 6.1 7.3 9.2 8.9 6.7 6.4 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain BRAP2 PF07576.7 ETO10303.1 - 0.022 14.3 1.1 0.029 13.9 0.3 1.5 1 1 0 1 1 1 0 BRCA1-associated protein 2 CheZ PF04344.8 ETO10304.1 - 0.00037 20.2 0.4 0.00053 19.7 0.3 1.1 1 0 0 1 1 1 1 Chemotaxis phosphatase, CheZ HTH_45 PF14947.1 ETO10305.1 - 0.038 13.8 0.1 0.061 13.1 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DUF3439 PF11921.3 ETO10306.1 - 0.11 12.2 7.8 0.42 10.3 5.4 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Utp14 PF04615.8 ETO10306.1 - 6.1 4.8 34.1 12 3.9 23.6 1.4 1 0 0 1 1 1 0 Utp14 protein Pkinase PF00069.20 ETO10308.1 - 8.3e-36 123.4 0.0 1.1e-35 123.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO10308.1 - 1.9e-12 46.8 0.0 2.8e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO10308.1 - 7e-05 21.9 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PEPcase PF00311.12 ETO10308.1 - 0.00079 17.4 0.1 0.0011 16.9 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase Complex1_LYR_1 PF13232.1 ETO10308.1 - 0.12 12.5 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Complex1_LYR-like TPR_17 PF13431.1 ETO10309.1 - 2.6e-05 24.0 0.3 0.24 11.6 0.2 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO10309.1 - 0.00018 21.1 0.3 0.74 9.5 0.0 2.8 2 0 0 2 2 2 2 TPR repeat DUF2492 PF10678.4 ETO10309.1 - 0.0089 16.0 2.0 0.024 14.7 0.2 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2492) TPR_1 PF00515.23 ETO10309.1 - 0.083 12.5 7.0 0.41 10.3 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETO10309.1 - 0.27 11.2 2.6 1.8 8.6 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat PT PF04886.7 ETO10312.1 - 0.023 14.0 11.6 0.023 14.0 8.0 5.2 1 1 2 3 3 3 0 PT repeat Herpes_gE PF02480.11 ETO10312.1 - 0.028 12.6 0.0 0.047 11.9 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SP_C-Propep PF08999.5 ETO10312.1 - 0.064 12.7 0.4 0.12 11.9 0.2 1.3 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF912 PF06024.7 ETO10312.1 - 0.17 11.9 0.1 0.17 11.9 0.0 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PHD PF00628.24 ETO10313.1 - 8e-07 28.6 13.1 8e-07 28.6 9.1 2.4 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 ETO10313.1 - 0.25 11.1 10.3 0.32 10.7 4.0 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Exo_endo_phos PF03372.18 ETO10314.1 - 0.00069 19.6 0.0 0.001 19.1 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Rb_C PF08934.5 ETO10314.1 - 0.82 9.2 6.7 2 8.0 4.7 1.7 1 1 0 1 1 1 0 Rb C-terminal domain DEAD PF00270.24 ETO10317.1 - 7.4e-06 25.5 0.0 1.8e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_29 PF13555.1 ETO10317.1 - 0.0086 15.5 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.1 ETO10317.1 - 0.011 15.5 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 ETO10317.1 - 0.11 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain WD40 PF00400.27 ETO10318.1 - 8.1e-10 38.2 7.4 0.23 11.4 0.5 6.0 5 0 0 5 5 5 4 WD domain, G-beta repeat ATG16 PF08614.6 ETO10319.1 - 0.0011 18.8 16.6 0.0016 18.2 11.5 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 ETO10319.1 - 0.013 15.3 14.9 0.024 14.4 6.4 2.3 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.6 ETO10319.1 - 0.023 13.3 16.5 0.07 11.7 11.4 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein CHD5 PF04420.9 ETO10319.1 - 0.048 13.3 7.7 0.33 10.6 1.2 3.2 2 1 0 2 2 2 0 CHD5-like protein Filament PF00038.16 ETO10319.1 - 0.1 12.0 16.1 0.12 11.8 5.9 2.1 1 1 1 2 2 2 0 Intermediate filament protein DUF4201 PF13870.1 ETO10319.1 - 0.11 11.9 15.3 0.25 10.7 10.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) DUF641 PF04859.7 ETO10319.1 - 0.23 11.1 10.7 0.81 9.4 1.4 2.6 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) TPR_MLP1_2 PF07926.7 ETO10319.1 - 0.25 11.1 17.4 4.4 7.0 7.2 3.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HAUS5 PF14817.1 ETO10319.1 - 0.3 9.5 11.5 0.61 8.5 7.5 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 5 DUF3138 PF11336.3 ETO10319.1 - 0.38 8.8 1.4 0.52 8.4 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) FliJ PF02050.11 ETO10319.1 - 1.4 8.9 14.6 3.3 7.7 4.2 2.9 2 1 0 2 2 2 0 Flagellar FliJ protein TSA PF03249.8 ETO10319.1 - 1.4 7.3 8.9 1.9 6.9 5.5 1.5 1 1 1 2 2 2 0 Type specific antigen Cluap1 PF10234.4 ETO10319.1 - 1.4 8.0 13.5 2.5 7.2 9.3 1.4 1 1 0 1 1 1 0 Clusterin-associated protein-1 Prefoldin_2 PF01920.15 ETO10319.1 - 1.6 8.5 20.3 2 8.2 1.3 3.7 2 1 2 4 4 4 0 Prefoldin subunit DASH_Spc34 PF08657.5 ETO10319.1 - 1.8 8.1 17.3 0.067 12.8 6.5 2.1 1 1 1 2 2 2 0 DASH complex subunit Spc34 DUF3584 PF12128.3 ETO10319.1 - 1.9 5.7 17.2 0.31 8.3 6.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Atg14 PF10186.4 ETO10319.1 - 2 7.2 12.2 4.3 6.1 8.5 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 RNA_pol_Rpb1_5 PF04998.12 ETO10319.1 - 2.4 7.3 5.3 3.4 6.8 3.7 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 CENP-H PF05837.7 ETO10319.1 - 2.4 8.3 14.0 0.59 10.3 1.5 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Seryl_tRNA_N PF02403.17 ETO10319.1 - 2.4 8.1 20.4 9.5 6.2 7.2 2.9 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain USP8_interact PF08941.5 ETO10319.1 - 2.9 7.2 7.1 5 6.4 1.0 2.4 2 0 0 2 2 2 0 USP8 interacting Tup_N PF08581.5 ETO10319.1 - 5.4 7.2 15.6 0.95 9.7 6.3 2.3 2 0 0 2 2 2 0 Tup N-terminal DUF4446 PF14584.1 ETO10319.1 - 6.1 6.6 10.5 10 5.9 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) DUF4200 PF13863.1 ETO10319.1 - 7.1 6.5 16.5 0.35 10.8 1.4 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) ORF6C PF10552.4 ETO10319.1 - 7.7 6.2 11.5 0.36 10.5 0.9 2.8 1 1 2 3 3 3 0 ORF6C domain DUF4407 PF14362.1 ETO10319.1 - 8.5 5.2 13.2 38 3.0 9.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4140 PF13600.1 ETO10319.1 - 9.6 6.7 12.0 16 6.0 0.2 3.4 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) FCH PF00611.18 ETO10320.1 - 0.0036 17.4 1.0 0.0036 17.4 0.7 5.1 4 2 2 6 6 6 2 Fes/CIP4, and EFC/F-BAR homology domain Spc24 PF08286.6 ETO10320.1 - 6.4 6.5 30.5 0.063 12.9 1.4 4.3 3 1 0 3 3 3 0 Spc24 subunit of Ndc80 Nucleoside_tran PF01733.13 ETO10320.1 - 6.4 5.8 10.3 1.4 8.0 0.3 2.8 2 1 0 2 2 2 0 Nucleoside transporter Img2 PF05046.9 ETO10320.1 - 7.1 6.9 13.1 22 5.3 0.0 4.3 2 1 1 3 3 3 0 Mitochondrial large subunit ribosomal protein (Img2) Pkinase PF00069.20 ETO10321.1 - 2.2e-48 164.6 0.4 3.1e-48 164.1 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO10321.1 - 3.5e-29 101.6 0.2 4.2e-29 101.3 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO10321.1 - 1.8e-05 23.8 0.3 0.042 12.8 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 ETO10321.1 - 0.00011 21.3 0.1 0.00015 20.8 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CCDC-167 PF15188.1 ETO10324.1 - 0.34 10.8 3.5 0.86 9.5 2.4 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Bcl-2_BAD PF10514.4 ETO10325.1 - 0.33 10.9 5.6 0.22 11.4 2.8 1.5 1 1 0 1 1 1 0 Pro-apoptotic Bcl-2 protein, BAD MFMR PF07777.6 ETO10325.1 - 2.3 8.1 8.0 3.6 7.4 5.5 1.3 1 0 0 1 1 1 0 G-box binding protein MFMR Gti1_Pac2 PF09729.4 ETO10325.1 - 5.9 6.7 7.4 20 5.0 5.1 1.9 1 1 0 1 1 1 0 Gti1/Pac2 family Ank_2 PF12796.2 ETO10326.1 - 7.3e-43 144.8 0.2 1e-17 64.1 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETO10326.1 - 4.6e-39 130.2 0.9 7.5e-09 34.9 0.0 7.0 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.1 ETO10326.1 - 2.5e-27 92.2 0.0 0.0001 22.2 0.0 6.9 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 ETO10326.1 - 2.3e-26 91.6 0.0 5.4e-06 26.7 0.0 5.3 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO10326.1 - 7.4e-26 89.5 0.1 9.7e-08 32.0 0.0 5.3 2 1 3 5 5 5 5 Ankyrin repeats (many copies) XPA_N PF01286.13 ETO10326.1 - 0.058 13.0 0.1 0.17 11.6 0.0 1.8 1 0 0 1 1 1 0 XPA protein N-terminal PNP_UDP_1 PF01048.15 ETO10329.1 - 1.1e-09 37.6 0.0 3.7e-05 22.8 0.0 2.0 2 0 0 2 2 2 2 Phosphorylase superfamily CcdB PF01845.12 ETO10329.1 - 0.073 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 CcdB protein DUF742 PF05331.6 ETO10329.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF742) Peptidase_M54 PF07998.6 ETO10330.1 - 6.2e-15 55.4 1.2 3.2e-14 53.1 0.1 2.2 2 0 0 2 2 2 1 Peptidase family M54 Reprolysin_5 PF13688.1 ETO10330.1 - 0.0016 18.4 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.19 ETO10330.1 - 0.0018 18.0 0.0 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.1 ETO10330.1 - 0.002 18.6 0.0 0.013 16.0 0.0 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 ETO10330.1 - 0.0034 17.4 0.0 0.0062 16.6 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DUF1025 PF06262.6 ETO10330.1 - 0.04 13.7 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase Reprolysin_4 PF13583.1 ETO10330.1 - 0.05 13.1 0.0 0.085 12.3 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.3 ETO10330.1 - 0.097 11.1 0.2 0.17 10.3 0.2 1.3 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M43 PF05572.8 ETO10330.1 - 0.11 12.0 0.7 0.19 11.3 0.1 1.6 2 0 0 2 2 2 0 Pregnancy-associated plasma protein-A Sec7_N PF12783.2 ETO10331.1 - 0.037 13.4 0.1 0.057 12.8 0.1 1.2 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal TPR_12 PF13424.1 ETO10332.1 - 5.6e-94 308.1 6.3 1.7e-24 85.5 0.0 5.3 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETO10332.1 - 5.4e-55 181.8 0.0 1.6e-09 37.3 0.0 7.7 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_11 PF13414.1 ETO10332.1 - 3.5e-50 167.5 22.0 1.2e-17 63.2 0.2 4.8 2 2 2 5 5 5 5 TPR repeat TPR_1 PF00515.23 ETO10332.1 - 4.4e-49 162.1 35.5 1e-08 34.4 0.3 8.4 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_7 PF13176.1 ETO10332.1 - 6.4e-46 150.5 8.0 4.5e-07 29.1 0.0 7.9 8 0 0 8 8 7 7 Tetratricopeptide repeat TPR_2 PF07719.12 ETO10332.1 - 4e-43 141.8 23.3 4.6e-06 26.1 0.6 8.0 8 0 0 8 8 7 7 Tetratricopeptide repeat TPR_8 PF13181.1 ETO10332.1 - 1.6e-40 133.8 42.9 4.3e-07 29.2 0.7 7.9 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_17 PF13431.1 ETO10332.1 - 6.8e-26 88.2 6.8 0.0025 17.8 0.0 8.3 8 0 0 8 8 7 7 Tetratricopeptide repeat TPR_16 PF13432.1 ETO10332.1 - 3.9e-17 62.4 0.0 8e-05 23.2 0.0 5.6 1 1 5 7 7 6 5 Tetratricopeptide repeat TPR_6 PF13174.1 ETO10332.1 - 1.3e-15 56.6 3.5 0.033 14.6 0.1 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO10332.1 - 2.8e-15 55.4 0.0 0.011 16.2 0.0 7.4 5 3 3 8 8 7 3 Tetratricopeptide repeat Peptidase_C14 PF00656.17 ETO10332.1 - 4.3e-12 46.2 0.4 1.1e-11 44.8 0.2 1.7 1 1 0 1 1 1 1 Caspase domain SNAP PF14938.1 ETO10332.1 - 4.1e-10 39.2 3.9 0.00046 19.4 1.1 3.7 1 1 2 3 3 3 2 Soluble NSF attachment protein, SNAP Apc3 PF12895.2 ETO10332.1 - 6.1e-10 39.0 15.7 0.0014 18.7 0.5 5.1 2 1 4 6 6 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO10332.1 - 1.3e-08 35.0 1.3 0.02 15.2 0.0 4.7 1 1 4 6 6 6 1 Tetratricopeptide repeat MIT PF04212.13 ETO10332.1 - 1.5e-08 34.3 29.7 0.02 14.7 0.5 7.0 6 1 1 7 7 7 5 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.4 ETO10332.1 - 1.6e-08 33.6 0.1 0.51 9.6 0.0 6.0 6 0 0 6 6 6 2 SHNi-TPR Sel1 PF08238.7 ETO10332.1 - 6.7e-06 26.5 8.0 14 6.4 0.1 7.1 7 0 0 7 7 7 0 Sel1 repeat PPR PF01535.15 ETO10332.1 - 2.1e-05 24.1 9.6 0.43 10.6 0.0 7.5 8 0 0 8 8 7 1 PPR repeat TPR_3 PF07720.7 ETO10332.1 - 4.6e-05 23.1 27.2 1.4 8.7 0.1 7.8 8 0 0 8 8 7 3 Tetratricopeptide repeat Ten1_2 PF15490.1 ETO10332.1 - 0.0072 15.8 0.0 13 5.3 0.0 4.3 1 1 4 5 5 5 0 Telomere-capping, CST complex subunit TPR_5 PF12688.2 ETO10332.1 - 0.0099 15.9 0.8 48 4.0 0.0 4.5 3 1 1 4 4 4 0 Tetratrico peptide repeat RPN7 PF10602.4 ETO10332.1 - 0.016 14.6 13.7 0.99 8.7 0.1 5.7 4 1 1 6 6 6 0 26S proteasome subunit RPN7 14-3-3 PF00244.15 ETO10332.1 - 0.048 12.7 5.6 0.079 12.0 0.1 3.6 2 1 4 6 6 6 0 14-3-3 protein TPR_9 PF13371.1 ETO10332.1 - 0.18 11.7 0.0 2.8 7.8 0.0 2.7 1 1 3 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.4 ETO10332.1 - 0.25 11.2 3.0 0.42 10.5 0.0 2.8 3 1 0 3 3 2 0 Tetratricopeptide repeat EzrA PF06160.7 ETO10333.1 - 0.0054 14.9 19.0 0.0091 14.2 13.2 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA zf-C3HC4_2 PF13923.1 ETO10333.1 - 0.029 14.3 0.9 0.12 12.3 0.6 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ATG16 PF08614.6 ETO10333.1 - 0.12 12.2 26.3 0.034 13.9 7.7 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) HrpB7 PF09486.5 ETO10333.1 - 0.13 12.1 13.8 0.064 13.1 2.9 2.4 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Bacillus_HBL PF05791.6 ETO10333.1 - 0.22 10.8 21.4 0.081 12.2 6.3 2.4 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Reo_sigmaC PF04582.7 ETO10333.1 - 0.32 10.1 13.5 0.15 11.2 4.9 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF641 PF04859.7 ETO10333.1 - 0.42 10.3 18.7 0.44 10.2 4.8 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Spc7 PF08317.6 ETO10333.1 - 0.58 8.7 26.0 1.2 7.7 17.2 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein MitMem_reg PF13012.1 ETO10333.1 - 0.81 9.8 14.9 0.91 9.6 9.1 2.0 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function TMF_DNA_bd PF12329.3 ETO10333.1 - 2.5 7.9 23.0 2 8.2 4.4 3.4 2 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding zf-RING-like PF08746.6 ETO10333.1 - 2.6 8.1 8.4 29 4.7 5.8 2.8 1 1 0 1 1 1 0 RING-like domain CENP-F_leu_zip PF10473.4 ETO10333.1 - 2.6 7.9 29.0 2.6 7.8 11.3 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin PF00261.15 ETO10333.1 - 3.4 6.7 21.2 0.29 10.2 7.3 2.0 1 1 1 2 2 2 0 Tropomyosin Tropomyosin_1 PF12718.2 ETO10333.1 - 5.5 6.8 25.9 9.4 6.0 8.6 2.7 1 1 1 2 2 2 0 Tropomyosin like IncA PF04156.9 ETO10333.1 - 5.8 6.4 31.9 1.3 8.6 18.8 2.0 1 1 1 2 2 2 0 IncA protein Ribosomal_S15 PF00312.17 ETO10333.1 - 8.5 6.2 11.0 0.79 9.5 2.0 2.6 1 1 1 2 2 2 0 Ribosomal protein S15 Pkinase PF00069.20 ETO10334.1 - 4.7e-54 183.2 0.1 9.1e-54 182.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO10334.1 - 1.8e-27 96.0 0.0 3.2e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 ETO10334.1 - 4.2e-07 30.3 1.5 8.7e-07 29.3 1.1 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.9 ETO10334.1 - 0.0006 18.9 0.3 0.0012 17.9 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETO10334.1 - 0.0039 16.1 0.7 0.3 9.9 0.0 2.5 1 1 1 2 2 2 2 Kinase-like RNase_P_Rpp14 PF01900.14 ETO10335.1 - 0.011 15.6 0.0 0.047 13.6 0.0 2.1 3 0 0 3 3 3 0 Rpp14/Pop5 family DUF3921 PF13060.1 ETO10335.1 - 0.094 12.5 0.2 0.24 11.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) TFIIE_alpha PF02002.12 ETO10336.1 - 0.022 14.2 0.4 0.037 13.5 0.3 1.4 1 0 0 1 1 1 0 TFIIE alpha subunit Tim54 PF11711.3 ETO10338.1 - 0.02 13.4 1.1 0.025 13.2 0.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Mito_fiss_reg PF05308.6 ETO10338.1 - 4.9 6.4 11.9 2.5 7.4 7.1 1.4 1 1 0 1 1 1 0 Mitochondrial fission regulator DUF912 PF06024.7 ETO10338.1 - 5.6 7.0 13.4 5.7 7.0 8.1 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) WD40 PF00400.27 ETO10340.1 - 1.5e-68 224.4 10.6 7.9e-13 47.7 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO10340.1 - 1.4e-09 37.9 0.5 0.0056 16.4 0.0 3.3 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO10340.1 - 8.1e-06 24.3 0.1 0.27 9.4 0.0 3.1 3 0 0 3 3 3 3 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO10340.1 - 5.7e-05 22.0 4.8 2.9 6.5 0.2 4.2 2 1 1 4 4 4 3 Nup133 N terminal like Nup160 PF11715.3 ETO10340.1 - 0.0002 19.6 8.5 4.4 5.3 0.1 5.3 2 2 3 6 6 6 3 Nucleoporin Nup120/160 DUF1652 PF07865.6 ETO10340.1 - 0.00094 18.7 0.1 4.8 6.8 0.0 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF1652) SGL PF08450.7 ETO10340.1 - 0.05 12.9 0.3 1.5 8.1 0.1 2.8 1 1 2 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region Resistin PF06954.6 ETO10340.1 - 0.092 13.0 0.3 19 5.6 0.0 3.8 3 1 1 4 4 4 0 Resistin Proteasome_A_N PF10584.4 ETO10340.1 - 0.25 10.7 8.4 10 5.5 0.1 4.7 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature NHL PF01436.16 ETO10340.1 - 0.33 10.9 2.2 5.6 7.1 0.1 3.2 3 0 0 3 3 3 0 NHL repeat Thioredoxin_6 PF13848.1 ETO10341.1 - 1.5e-17 63.9 2.1 2.7e-16 59.9 0.0 3.2 3 1 0 3 3 3 1 Thioredoxin-like domain Neur_chan_memb PF02932.11 ETO10341.1 - 0.18 11.6 3.3 0.32 10.8 2.2 1.8 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3295 PF11702.3 ETO10341.1 - 4.9 6.0 7.2 8.2 5.2 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Neogenin_C PF06583.7 ETO10342.1 - 0.032 13.8 0.3 0.035 13.6 0.2 1.0 1 0 0 1 1 1 0 Neogenin C-terminus NST1 PF13945.1 ETO10342.1 - 0.056 13.5 0.2 0.075 13.1 0.1 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF3522 PF12036.3 ETO10343.1 - 0.00014 21.7 0.6 0.00018 21.3 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) PTPA PF03095.10 ETO10344.1 - 1.9e-22 79.8 0.7 1.8e-17 63.4 0.0 2.1 1 1 1 2 2 2 2 Phosphotyrosyl phosphate activator (PTPA) protein DUF3439 PF11921.3 ETO10345.1 - 0.071 12.8 1.4 0.1 12.3 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF3441 PF11923.3 ETO10346.1 - 1.4e-17 63.2 0.0 1.4e-17 63.2 0.0 4.5 3 1 0 3 3 3 1 Domain of unknown function (DUF3441) DUF814 PF05670.8 ETO10347.1 - 3.4e-05 23.6 0.1 0.0047 16.7 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF814) Nucleoplasmin PF03066.10 ETO10347.1 - 6.1e-05 22.5 30.0 0.0045 16.5 4.5 3.9 3 0 0 3 3 3 2 Nucleoplasmin Sigma70_ner PF04546.8 ETO10347.1 - 0.0051 16.4 43.4 0.013 15.1 5.6 3.6 3 0 0 3 3 3 2 Sigma-70, non-essential region FAM176 PF14851.1 ETO10347.1 - 0.11 12.1 35.2 0.016 14.8 3.7 4.8 4 1 0 4 4 4 0 FAM176 family Myc_N PF01056.13 ETO10347.1 - 0.17 11.0 24.8 0.088 11.9 3.0 3.3 3 0 0 3 3 3 0 Myc amino-terminal region Nop14 PF04147.7 ETO10347.1 - 0.33 8.8 62.5 0.069 11.0 13.7 3.2 1 1 1 3 3 3 0 Nop14-like family RXT2_N PF08595.6 ETO10347.1 - 3.2 7.5 31.1 1.3 8.7 6.5 4.0 3 0 0 3 3 3 0 RXT2-like, N-terminal TLP-20 PF06088.6 ETO10347.1 - 9.5 5.8 31.0 0.17 11.5 3.0 3.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) WD40 PF00400.27 ETO10351.1 - 3e-06 26.9 1.1 0.028 14.3 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat Lipocalin PF00061.18 ETO10352.1 - 0.00053 19.9 1.4 0.00053 19.9 1.0 1.8 1 1 1 2 2 2 1 Lipocalin / cytosolic fatty-acid binding protein family DUF3255 PF11631.3 ETO10352.1 - 0.089 12.4 0.2 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3255) Mitofilin PF09731.4 ETO10353.1 - 0.00035 19.3 21.5 0.00035 19.3 14.9 5.2 1 1 3 4 4 4 1 Mitochondrial inner membrane protein Orthopox_F14 PF06076.7 ETO10354.1 - 0.044 13.8 1.0 0.075 13.1 0.7 1.3 1 0 0 1 1 1 0 Orthopoxvirus F14 protein GlcNAc PF11397.3 ETO10355.1 - 1.2e-50 172.6 0.0 6.4e-33 114.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase (GlcNAc) Abhydrolase_9_N PF15420.1 ETO10356.1 - 0.0046 16.7 1.1 0.0046 16.7 0.8 2.5 3 1 0 3 3 3 1 Alpha/beta-hydrolase family N-terminus Lactamase_B PF00753.22 ETO10357.1 - 1.6e-17 63.8 0.0 2.3e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETO10357.1 - 0.01 15.4 0.1 0.023 14.2 0.0 1.6 1 1 0 1 1 1 0 Beta-lactamase superfamily domain COG5 PF10392.4 ETO10358.1 - 0.00021 21.2 0.9 0.00041 20.2 0.4 1.6 1 1 1 2 2 2 1 Golgi transport complex subunit 5 Apolipoprotein PF01442.13 ETO10358.1 - 0.0038 16.7 3.3 0.017 14.5 2.3 1.8 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain APG6 PF04111.7 ETO10358.1 - 0.0047 16.0 7.3 0.0051 15.8 5.1 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 Cast PF10174.4 ETO10358.1 - 0.0065 14.5 6.4 0.0073 14.4 4.4 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Ribosomal_L17 PF01196.14 ETO10358.1 - 0.0072 16.8 0.2 0.01 16.3 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L17 DUF4200 PF13863.1 ETO10358.1 - 0.0075 16.2 11.9 0.012 15.5 8.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4200) WEMBL PF05701.6 ETO10358.1 - 0.013 13.9 6.9 0.016 13.7 4.8 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF972 PF06156.8 ETO10358.1 - 0.017 15.4 9.9 0.029 14.7 2.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) K-box PF01486.12 ETO10358.1 - 0.022 14.5 3.7 0.024 14.4 1.1 2.1 1 1 1 2 2 2 0 K-box region DUF1571 PF07608.6 ETO10358.1 - 0.028 13.5 0.2 0.031 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1571) DUF1977 PF09320.6 ETO10358.1 - 0.031 14.5 0.9 0.043 14.0 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1977) IncA PF04156.9 ETO10358.1 - 0.058 12.9 7.6 0.07 12.7 5.3 1.1 1 0 0 1 1 1 0 IncA protein AAA_13 PF13166.1 ETO10358.1 - 0.059 11.8 9.4 0.056 11.9 6.5 1.1 1 0 0 1 1 1 0 AAA domain DUF2968 PF11180.3 ETO10358.1 - 0.064 12.6 2.7 0.078 12.3 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Syntaxin-6_N PF09177.6 ETO10358.1 - 0.075 13.4 3.1 0.12 12.8 2.2 1.3 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DUF3496 PF12001.3 ETO10358.1 - 0.075 13.2 3.4 0.1 12.8 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) KaiC PF06745.8 ETO10358.1 - 0.08 12.0 0.9 0.099 11.7 0.6 1.3 1 0 0 1 1 1 0 KaiC Rootletin PF15035.1 ETO10358.1 - 0.084 12.8 4.8 0.096 12.6 3.3 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DREPP PF05558.7 ETO10358.1 - 0.097 12.5 2.7 0.11 12.3 1.9 1.1 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide Prefoldin PF02996.12 ETO10358.1 - 0.099 12.2 6.7 0.05 13.2 2.8 1.8 1 1 1 2 2 2 0 Prefoldin subunit PG_binding_4 PF12229.3 ETO10358.1 - 0.1 12.8 2.7 0.078 13.2 0.5 1.7 2 0 0 2 2 2 0 Putative peptidoglycan binding domain Cut12 PF11500.3 ETO10358.1 - 0.12 12.0 3.1 0.16 11.6 2.2 1.2 1 0 0 1 1 1 0 Spindle pole body formation-associated protein DUF1664 PF07889.7 ETO10358.1 - 0.13 12.0 3.6 0.32 10.7 2.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Cluap1 PF10234.4 ETO10358.1 - 0.14 11.2 6.4 0.2 10.8 4.4 1.3 1 1 0 1 1 1 0 Clusterin-associated protein-1 DUF4298 PF14131.1 ETO10358.1 - 0.16 11.8 4.6 1 9.2 0.2 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4298) Spc7 PF08317.6 ETO10358.1 - 0.19 10.3 9.4 0.2 10.2 6.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.7 ETO10358.1 - 0.2 11.4 3.6 0.3 10.9 2.5 1.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.1 ETO10358.1 - 0.28 11.5 10.2 0.12 12.6 2.9 2.4 1 1 1 2 2 2 0 Snapin/Pallidin MbeD_MobD PF04899.7 ETO10358.1 - 0.3 11.0 2.1 0.58 10.1 0.3 2.0 1 1 1 2 2 2 0 MbeD/MobD like DUF948 PF06103.6 ETO10358.1 - 0.33 10.8 3.8 0.34 10.7 1.7 1.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Occludin_ELL PF07303.8 ETO10358.1 - 0.36 11.5 4.6 0.4 11.4 0.6 2.2 1 1 1 2 2 2 0 Occludin homology domain DUF2205 PF10224.4 ETO10358.1 - 0.38 10.3 4.7 0.57 9.7 3.2 1.5 1 1 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) zf-C4H2 PF10146.4 ETO10358.1 - 0.39 10.6 5.5 0.42 10.6 3.8 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein CENP-F_leu_zip PF10473.4 ETO10358.1 - 0.49 10.2 8.7 0.33 10.7 2.2 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.10 ETO10358.1 - 0.61 9.6 8.4 0.13 11.7 2.8 2.2 2 1 1 3 3 2 0 Septum formation initiator V_ATPase_I PF01496.14 ETO10358.1 - 0.61 7.8 6.0 0.67 7.7 4.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family End3 PF12761.2 ETO10358.1 - 0.72 9.4 7.0 0.89 9.1 4.8 1.1 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 TMF_DNA_bd PF12329.3 ETO10358.1 - 0.72 9.7 8.3 0.16 11.8 3.3 1.8 2 0 0 2 2 1 0 TATA element modulatory factor 1 DNA binding Uteroglobin PF01099.12 ETO10358.1 - 0.84 9.4 6.3 1 9.1 2.3 2.4 1 1 1 2 2 2 0 Uteroglobin family DUF342 PF03961.8 ETO10358.1 - 0.84 7.9 9.4 0.79 8.0 6.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SlyX PF04102.7 ETO10358.1 - 0.89 9.9 5.5 2.8 8.4 0.3 2.7 1 1 2 3 3 3 0 SlyX CCDC155 PF14662.1 ETO10358.1 - 0.9 9.1 9.9 1.2 8.6 6.8 1.4 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 Spc24 PF08286.6 ETO10358.1 - 0.92 9.2 7.7 0.28 10.9 2.5 1.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Fib_alpha PF08702.5 ETO10358.1 - 1.2 9.2 8.1 1.8 8.7 4.4 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CDC37_N PF03234.9 ETO10358.1 - 1.4 9.2 7.0 3.7 7.8 4.8 1.7 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding FliJ PF02050.11 ETO10358.1 - 1.4 8.9 11.4 5 7.2 0.9 2.4 1 1 0 2 2 2 0 Flagellar FliJ protein Prefoldin_2 PF01920.15 ETO10358.1 - 2.2 8.0 12.4 0.12 12.1 3.3 2.3 2 0 0 2 2 2 0 Prefoldin subunit IATP PF04568.7 ETO10358.1 - 3.2 7.8 6.6 0.72 9.9 2.3 1.7 2 0 0 2 2 1 0 Mitochondrial ATPase inhibitor, IATP ACCA PF03255.9 ETO10358.1 - 3.6 7.1 6.2 5.1 6.6 0.9 2.0 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit YlbD_coat PF14071.1 ETO10358.1 - 4.1 7.4 8.0 18 5.3 5.0 2.2 1 1 0 1 1 1 0 Putative coat protein FlxA PF14282.1 ETO10358.1 - 4.6 7.2 11.9 0.4 10.6 5.0 1.8 1 1 0 2 2 1 0 FlxA-like protein Microtub_assoc PF07989.6 ETO10358.1 - 5 7.0 11.5 1.1 9.0 3.3 2.5 1 1 1 2 2 1 0 Microtubule associated CENP-Q PF13094.1 ETO10358.1 - 6.6 6.7 9.6 0.77 9.7 2.7 2.0 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit HSBP1 PF06825.7 ETO10358.1 - 6.6 6.3 13.1 1.4 8.5 1.7 3.0 2 1 1 3 3 3 0 Heat shock factor binding protein 1 eIF3_subunit PF08597.5 ETO10359.1 - 1.5 8.3 8.6 4.5 6.7 6.0 1.7 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit EMP70 PF02990.11 ETO10360.1 - 7e-49 166.6 21.3 7e-49 166.6 14.8 1.5 2 0 0 2 2 2 1 Endomembrane protein 70 Asp PF00026.18 ETO10361.1 - 8.8e-48 163.1 2.7 1.1e-46 159.5 1.8 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETO10361.1 - 4.9e-07 29.8 0.2 6.3e-06 26.2 0.2 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 ETO10361.1 - 0.0039 17.6 0.0 0.0064 16.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 ETO10361.1 - 0.043 13.6 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-ribbon_3 PF13248.1 ETO10361.1 - 0.088 12.0 0.3 0.27 10.5 0.2 1.8 1 0 0 1 1 1 0 zinc-ribbon domain Asp PF00026.18 ETO10362.1 - 5.3e-20 71.8 0.1 6.4e-20 71.6 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Herpes_LMP1 PF05297.6 ETO10363.1 - 0.028 13.3 1.9 0.053 12.4 1.3 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF1510 PF07423.6 ETO10363.1 - 0.43 9.9 15.4 0.66 9.3 10.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nop14 PF04147.7 ETO10363.1 - 8.2 4.1 22.8 11 3.7 15.8 1.1 1 0 0 1 1 1 0 Nop14-like family Chromate_transp PF02417.10 ETO10365.1 - 2e-28 99.1 17.4 5.1e-28 97.7 12.1 1.7 1 1 0 1 1 1 1 Chromate transporter DUF3993 PF13158.1 ETO10366.1 - 0.11 12.3 0.5 0.18 11.5 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3993) REV PF00424.13 ETO10368.1 - 5.7 6.9 8.8 0.24 11.3 0.6 2.2 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Pkinase PF00069.20 ETO10369.1 - 0.00074 18.7 0.3 0.0013 17.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain DUF506 PF04720.7 ETO10369.1 - 0.076 12.6 0.1 0.088 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Pkinase PF00069.20 ETO10370.1 - 4.3e-16 58.8 2.6 3.8e-15 55.7 0.7 2.2 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO10370.1 - 2.7e-09 36.4 1.0 1.4e-08 34.1 0.1 2.4 1 1 2 4 4 4 1 Protein tyrosine kinase Kdo PF06293.9 ETO10370.1 - 0.031 13.3 0.4 0.045 12.8 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC_tran PF00005.22 ETO10371.1 - 5.8e-18 65.5 0.0 1.2e-17 64.4 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 ETO10371.1 - 1.1e-06 28.8 0.4 5.4e-05 23.2 0.3 2.2 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 ETO10371.1 - 1.1e-05 24.7 0.0 2.7e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 ETO10371.1 - 0.00055 20.7 0.3 0.0013 19.5 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETO10371.1 - 0.0016 18.4 0.0 0.0022 18.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 ETO10371.1 - 0.012 15.4 0.2 0.039 13.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 ETO10371.1 - 0.014 15.0 0.0 0.072 12.7 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 ETO10371.1 - 0.021 15.1 0.1 0.044 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 ETO10371.1 - 0.036 13.9 0.4 0.14 12.0 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 ETO10371.1 - 0.039 14.2 1.8 0.8 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.15 ETO10371.1 - 0.042 12.5 0.0 0.052 12.2 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit AAA_15 PF13175.1 ETO10371.1 - 0.043 12.8 3.6 0.081 11.9 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.1 ETO10371.1 - 0.047 13.8 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 ETO10371.1 - 0.053 12.9 0.0 0.11 11.8 0.0 1.5 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 ETO10371.1 - 0.078 11.8 1.1 0.24 10.2 0.8 1.8 1 1 0 1 1 1 0 NB-ARC domain PduV-EutP PF10662.4 ETO10371.1 - 0.094 12.2 0.0 0.32 10.4 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.17 ETO10371.1 - 0.1 12.0 0.1 0.25 10.7 0.0 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_28 PF13521.1 ETO10371.1 - 0.12 12.3 0.0 0.53 10.2 0.0 2.1 2 1 1 3 3 2 0 AAA domain ATP-synt_ab PF00006.20 ETO10371.1 - 0.16 11.4 0.0 0.37 10.2 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain HSP70 PF00012.15 ETO10372.1 - 1.6e-201 670.4 6.1 2.2e-138 461.8 0.1 3.0 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 ETO10372.1 - 7.8e-11 41.1 0.9 2.1e-07 29.8 0.1 3.1 3 1 0 3 3 3 2 MreB/Mbl protein FtsA PF14450.1 ETO10372.1 - 0.0036 17.1 2.7 6.6 6.5 0.8 3.8 2 1 0 2 2 2 2 Cell division protein FtsA FGGY_C PF02782.11 ETO10372.1 - 0.0071 15.9 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain ABC2_membrane_5 PF13346.1 ETO10373.1 - 0.053 12.8 2.8 0.078 12.2 2.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1079 PF06435.6 ETO10373.1 - 0.075 12.9 1.4 0.17 11.8 1.0 1.7 1 0 0 1 1 1 0 Repeat of unknown function (DUF1079) ABC_tran PF00005.22 ETO10374.1 - 1.8e-20 73.6 0.1 5.1e-20 72.1 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC_tran_2 PF12848.2 ETO10374.1 - 1.4e-15 56.8 3.1 2.6e-15 55.9 2.1 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 ETO10374.1 - 3.6e-09 36.9 4.4 7.2e-07 29.4 3.1 2.5 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 ETO10374.1 - 2.7e-07 30.0 0.7 6.9e-07 28.7 0.1 1.9 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain ArgK PF03308.11 ETO10374.1 - 0.00029 19.7 0.1 0.0005 18.9 0.0 1.3 1 0 0 1 1 1 1 ArgK protein Miro PF08477.8 ETO10374.1 - 0.0047 17.4 0.1 0.017 15.5 0.0 2.0 3 0 0 3 3 1 1 Miro-like protein AAA_33 PF13671.1 ETO10374.1 - 0.0084 15.9 0.0 0.023 14.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETO10374.1 - 0.0095 16.2 0.1 0.24 11.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain DUF87 PF01935.12 ETO10374.1 - 0.01 15.6 0.5 0.027 14.2 0.0 1.9 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_29 PF13555.1 ETO10374.1 - 0.011 15.2 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.1 ETO10374.1 - 0.018 14.9 0.1 0.19 11.6 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MobB PF03205.9 ETO10374.1 - 0.019 14.6 0.0 0.04 13.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 ETO10374.1 - 0.036 14.0 0.5 0.14 12.0 0.4 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.1 ETO10374.1 - 0.066 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Thymidylate_kin PF02223.12 ETO10374.1 - 0.073 12.4 1.3 3 7.1 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase AAA_17 PF13207.1 ETO10374.1 - 0.09 13.5 0.3 0.23 12.3 0.2 1.8 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 ETO10374.1 - 0.095 12.1 0.3 0.41 10.0 0.0 2.1 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain DUF258 PF03193.11 ETO10374.1 - 0.1 11.7 0.1 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 ETO10374.1 - 0.12 12.4 0.2 0.83 9.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain L_biotic_typeA PF04604.8 ETO10374.1 - 0.17 11.5 0.5 0.53 9.9 0.0 2.1 2 0 0 2 2 2 0 Type-A lantibiotic AAA_23 PF13476.1 ETO10374.1 - 0.23 11.7 3.7 0.81 9.9 0.2 2.3 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 ETO10374.1 - 0.74 8.7 6.9 3.9 6.4 1.8 2.5 2 1 0 2 2 2 0 AAA ATPase domain Metallophos PF00149.23 ETO10375.1 - 7.2e-30 103.8 0.0 1.2e-29 103.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 ETO10375.1 - 0.017 15.0 0.1 0.05 13.6 0.0 1.8 1 0 0 1 1 1 0 PPP5 TPR repeat region DUF3401 PF11881.3 ETO10376.1 - 0.0016 17.8 1.3 0.002 17.5 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3401) COG5 PF10392.4 ETO10376.1 - 0.0068 16.3 1.6 0.01 15.8 1.1 1.4 1 0 0 1 1 1 1 Golgi transport complex subunit 5 ApoLp-III PF07464.6 ETO10376.1 - 0.065 13.2 8.2 0.081 12.9 5.7 1.1 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) 7TMR-HDED PF07697.6 ETO10376.1 - 0.1 12.3 8.0 0.17 11.5 5.6 1.3 1 1 0 1 1 1 0 7TM-HD extracellular Bacillus_HBL PF05791.6 ETO10376.1 - 0.2 11.0 9.0 0.036 13.4 3.4 1.8 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) FlxA PF14282.1 ETO10376.1 - 0.25 11.3 14.7 0.62 10.0 9.7 1.8 1 1 1 2 2 2 0 FlxA-like protein PCYCGC PF13798.1 ETO10376.1 - 0.26 10.9 2.8 0.19 11.3 0.5 1.7 1 1 1 2 2 2 0 Protein of unknown function with PCYCGC motif Herpes_UL6 PF01763.11 ETO10376.1 - 0.44 8.6 5.6 0.54 8.3 3.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF643 PF04867.7 ETO10376.1 - 0.56 10.6 9.8 0.1 13.0 2.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF643) Striatin PF08232.7 ETO10376.1 - 0.79 10.0 8.4 0.35 11.1 4.0 1.6 1 1 1 2 2 2 0 Striatin family DUF4364 PF14277.1 ETO10376.1 - 0.98 9.0 6.1 0.099 12.2 0.4 2.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4364) Histone_HNS PF00816.16 ETO10376.1 - 1.2 9.6 7.1 5.9 7.4 4.9 2.2 1 1 0 1 1 1 0 H-NS histone family Latarcin PF10279.4 ETO10376.1 - 1.2 9.3 5.0 3.3 7.9 3.4 1.8 1 1 0 1 1 1 0 Latarcin precursor HSP70 PF00012.15 ETO10376.1 - 1.6 6.5 9.9 2 6.2 6.9 1.3 1 0 0 1 1 1 0 Hsp70 protein DUF4407 PF14362.1 ETO10376.1 - 1.7 7.4 6.9 2.1 7.2 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4404 PF14357.1 ETO10376.1 - 1.9 8.9 5.6 0.41 11.0 0.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Jnk-SapK_ap_N PF09744.4 ETO10376.1 - 9.7 6.1 15.2 0.55 10.2 5.1 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DNA_pol_viral_N PF00242.12 ETO10377.1 - 0.41 9.6 25.8 0.53 9.2 17.9 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain RasGEF PF00617.14 ETO10378.1 - 2.4e-32 112.2 4.3 3.3e-32 111.7 3.0 1.2 1 0 0 1 1 1 1 RasGEF domain Casc1 PF12366.3 ETO10378.1 - 0.058 12.8 0.1 0.058 12.8 0.1 2.1 3 0 0 3 3 3 0 Cancer susceptibility candidate 1 NADase_NGA PF07461.6 ETO10378.1 - 0.078 11.6 2.1 0.5 8.9 0.1 2.1 2 0 0 2 2 2 0 Nicotine adenine dinucleotide glycohydrolase (NADase) Glyco_transf_64 PF09258.5 ETO10379.1 - 3.7e-21 75.4 1.4 3.4e-20 72.2 1.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 64 domain Pkinase PF00069.20 ETO10380.1 - 3.3e-07 29.7 0.3 1.3e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Cwf_Cwc_15 PF04889.7 ETO10382.1 - 0.018 14.7 1.2 0.021 14.5 0.8 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3347 PF11827.3 ETO10382.1 - 0.066 13.2 0.2 0.072 13.0 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Presenilin PF01080.12 ETO10382.1 - 0.069 11.9 0.0 0.075 11.8 0.0 1.0 1 0 0 1 1 1 0 Presenilin AAA_12 PF13087.1 ETO10383.1 - 3.4e-40 137.5 0.1 2e-38 131.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 ETO10385.1 - 3e-27 95.5 0.6 5.5e-27 94.7 0.4 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 ETO10385.1 - 3.5e-15 56.7 6.6 4e-14 53.2 2.2 2.6 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 ETO10385.1 - 1.6e-05 24.2 2.0 5.8e-05 22.4 1.4 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 ETO10385.1 - 0.00035 20.9 8.3 0.0014 18.9 6.0 2.0 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 ETO10385.1 - 0.0048 16.3 0.3 0.6 9.5 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_29 PF13555.1 ETO10385.1 - 0.0049 16.3 0.1 0.011 15.2 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 ETO10385.1 - 0.0067 16.3 0.0 0.059 13.2 0.0 2.6 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ResIII PF04851.10 ETO10385.1 - 0.012 15.4 0.1 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UPF0079 PF02367.12 ETO10385.1 - 0.024 14.2 0.3 0.062 12.9 0.2 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 ETO10385.1 - 0.046 12.9 0.2 0.078 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SRP54 PF00448.17 ETO10385.1 - 0.071 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.1 ETO10385.1 - 0.12 12.2 0.0 0.88 9.4 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 ETO10385.1 - 0.2 11.5 0.2 0.4 10.6 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain 7TM_transglut PF14402.1 ETO10387.1 - 0.95 8.3 3.2 1.7 7.5 2.2 1.3 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase HlyD PF00529.15 ETO10387.1 - 9.3 5.4 13.2 0.4 9.9 4.0 2.2 2 1 0 2 2 2 0 HlyD family secretion protein BTB PF00651.26 ETO10388.1 - 1.8e-12 47.2 2.2 4.1e-12 46.0 0.5 2.0 2 0 0 2 2 2 1 BTB/POZ domain DUF936 PF06075.7 ETO10389.1 - 0.042 12.7 6.6 0.053 12.4 4.6 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DUF1609 PF07753.6 ETO10389.1 - 0.16 11.2 3.0 0.27 10.5 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1609) MFS_1 PF07690.11 ETO10390.1 - 0.0031 16.2 3.1 0.0079 14.9 1.2 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4149 PF13664.1 ETO10390.1 - 0.063 13.3 0.4 0.35 10.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) Nodulin-like PF06813.8 ETO10391.1 - 1.1e-19 70.6 22.4 9.3e-19 67.6 6.4 3.0 3 0 0 3 3 3 2 Nodulin-like DUF2370 PF10176.4 ETO10391.1 - 0.32 10.2 0.0 0.32 10.2 0.0 3.2 4 1 1 5 5 5 0 Protein of unknown function (DUF2370) Dev_Cell_Death PF10539.4 ETO10394.1 - 5.4e-16 58.3 0.0 1.2e-15 57.1 0.0 1.6 2 0 0 2 2 2 1 Development and cell death domain YtxC PF08812.6 ETO10394.1 - 0.21 11.0 0.1 0.33 10.4 0.1 1.2 1 0 0 1 1 1 0 YtxC-like family Dicty_REP PF05086.7 ETO10394.1 - 2.5 5.7 11.2 3.1 5.4 7.8 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 ETO10395.1 - 1.4 8.7 19.8 6.9 6.4 13.7 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SlyX PF04102.7 ETO10396.1 - 2.5 8.5 10.1 17 5.9 0.7 3.4 2 0 0 2 2 2 0 SlyX Prefoldin_2 PF01920.15 ETO10396.1 - 3.8 7.3 17.9 2.7 7.8 5.7 4.3 1 1 2 3 3 3 0 Prefoldin subunit GEMIN8 PF15348.1 ETO10398.1 - 0.02 14.9 0.5 0.041 13.9 0.3 1.5 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DUF2899 PF11449.3 ETO10400.1 - 0.016 14.3 3.6 0.053 12.6 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2899) UPF0233 PF06781.7 ETO10400.1 - 0.06 12.9 3.6 0.2 11.3 0.0 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) WD40 PF00400.27 ETO10401.1 - 9.4e-16 57.0 4.5 3.3e-09 36.2 0.1 3.4 3 1 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO10401.1 - 0.00041 18.6 0.1 0.044 11.9 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF1510 PF07423.6 ETO10402.1 - 0.1 11.9 1.3 0.14 11.4 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF3139 PF11337.3 ETO10402.1 - 0.23 11.7 5.1 0.45 10.8 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) Peptidase_S49_N PF08496.5 ETO10402.1 - 0.42 10.4 2.1 0.68 9.7 1.5 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Baculo_11_kDa PF06143.6 ETO10402.1 - 1.3 8.3 5.0 2.5 7.5 3.4 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family WD40 PF00400.27 ETO10403.1 - 1.2e-51 170.8 22.2 1.3e-10 40.7 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO10403.1 - 8.2e-10 37.4 4.2 0.0052 14.9 0.2 4.8 1 1 4 5 5 5 4 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO10403.1 - 2.2e-05 24.2 0.0 0.98 9.3 0.0 4.3 2 1 2 4 4 4 1 Domain of unknown function (DUF3601) Nucleoporin_N PF08801.6 ETO10403.1 - 0.00033 19.5 3.3 3.1 6.4 0.0 3.8 1 1 2 4 4 4 3 Nup133 N terminal like MerR_1 PF13411.1 ETO10403.1 - 0.15 11.8 1.2 8 6.3 0.0 3.9 5 0 0 5 5 5 0 MerR HTH family regulatory protein DUF678 PF05077.7 ETO10403.1 - 2.4 8.2 5.6 2.5 8.1 0.1 3.5 2 1 2 5 5 5 0 Protein of unknown function (DUF678) SGT1 PF07093.6 ETO10404.1 - 0.49 8.7 9.2 0.55 8.5 6.4 1.0 1 0 0 1 1 1 0 SGT1 protein Tom37_C PF11801.3 ETO10404.1 - 1.4 8.7 6.5 1.5 8.6 4.5 1.1 1 0 0 1 1 1 0 Tom37 C-terminal domain RNase_H2-Ydr279 PF09468.5 ETO10404.1 - 1.4 8.0 5.4 1.6 7.8 3.7 1.0 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) YqfQ PF14181.1 ETO10404.1 - 1.8 8.6 11.4 2.2 8.3 7.9 1.0 1 0 0 1 1 1 0 YqfQ-like protein DUF3381 PF11861.3 ETO10404.1 - 2.9 7.3 19.2 3.3 7.1 13.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF3682 PF12446.3 ETO10404.1 - 3 8.1 21.9 3.8 7.8 15.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Pox_RNA_Pol_19 PF05320.7 ETO10404.1 - 4 7.1 11.9 5 6.8 8.3 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit HSP90 PF00183.13 ETO10404.1 - 4.5 5.5 18.5 4.6 5.5 12.8 1.0 1 0 0 1 1 1 0 Hsp90 protein SelP_N PF04592.9 ETO10404.1 - 6.4 6.0 6.8 7 5.9 4.7 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region VID27 PF08553.5 ETO10404.1 - 6.6 4.8 20.0 6.7 4.7 13.8 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein TRAP_alpha PF03896.11 ETO10404.1 - 6.9 5.5 13.7 7.4 5.4 9.5 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit TLP-20 PF06088.6 ETO10404.1 - 8.2 6.0 8.2 9.7 5.8 5.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF2500 PF10694.4 ETO10407.1 - 0.041 13.8 0.7 0.06 13.3 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) YMF19 PF02326.10 ETO10407.1 - 2.3 8.8 8.6 0.94 10.0 2.8 2.2 1 1 1 2 2 2 0 Plant ATP synthase F0 PUL PF08324.6 ETO10408.1 - 7.2e-10 38.1 1.0 1e-09 37.5 0.7 1.3 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 ETO10408.1 - 1.9e-08 34.3 0.0 1.3e-07 31.5 0.0 2.3 2 0 0 2 2 2 1 PFU (PLAA family ubiquitin binding) DEP PF00610.16 ETO10409.1 - 4.8e-39 131.9 2.6 1.3e-18 66.4 0.3 2.2 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) IDEAL PF08858.5 ETO10409.1 - 0.012 15.0 3.7 1.9 8.0 0.3 2.6 2 0 0 2 2 2 0 IDEAL domain zf-Di19 PF05605.7 ETO10409.1 - 0.012 15.6 0.6 0.86 9.7 0.0 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Cag12 PF13117.1 ETO10409.1 - 0.019 14.8 3.4 0.86 9.5 0.2 2.8 3 0 0 3 3 3 0 Cag pathogenicity island protein Cag12 DEP PF00610.16 ETO10410.1 - 5.8e-16 58.0 2.2 1.7e-11 43.6 0.0 3.4 3 0 0 3 3 3 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CAP_GLY PF01302.20 ETO10411.1 - 0.019 14.6 0.3 0.059 13.0 0.2 1.8 1 1 0 1 1 1 0 CAP-Gly domain TFIIA PF03153.8 ETO10411.1 - 1.7 8.4 55.3 1.1 9.1 25.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF1027 PF06265.6 ETO10413.1 - 0.026 14.3 0.9 0.23 11.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1027) NUC153 PF08159.7 ETO10414.1 - 3.6e-12 45.6 0.7 1e-11 44.1 0.5 1.9 1 0 0 1 1 1 1 NUC153 domain DUF2316 PF10078.4 ETO10414.1 - 0.03 14.3 3.0 0.046 13.7 1.2 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) Herpes_UL25 PF01499.11 ETO10414.1 - 1.4 7.1 12.0 0.14 10.4 2.0 2.2 2 0 0 2 2 2 0 Herpesvirus UL25 family H_PPase PF03030.11 ETO10415.1 - 6.2e-231 768.3 22.1 1.6e-173 578.6 8.6 2.0 2 0 0 2 2 2 2 Inorganic H+ pyrophosphatase DUF4231 PF14015.1 ETO10415.1 - 0.018 14.9 0.5 0.018 14.9 0.3 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) Arm PF00514.18 ETO10416.1 - 1.3e-28 97.7 1.0 4.9e-05 23.0 0.0 5.8 5 1 0 5 5 5 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 ETO10416.1 - 6.9e-07 29.4 0.0 0.014 15.6 0.0 3.2 2 1 0 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 ETO10416.1 - 3.2e-06 27.4 0.0 0.048 14.1 0.0 3.8 2 1 0 3 3 3 2 HEAT-like repeat IBB PF01749.15 ETO10416.1 - 2.1e-05 24.5 10.0 2.1e-05 24.5 6.9 1.6 2 0 0 2 2 2 1 Importin beta binding domain HEAT PF02985.17 ETO10416.1 - 0.0061 16.5 0.0 2.3 8.4 0.0 4.1 5 0 0 5 5 5 1 HEAT repeat Secretin_N_2 PF07655.8 ETO10416.1 - 0.19 12.1 3.5 0.31 11.4 2.4 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain PseudoU_synth_1 PF01416.15 ETO10418.1 - 5.2e-26 91.1 0.4 3.1e-13 50.0 0.2 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase LAG1-DNAbind PF09271.6 ETO10418.1 - 0.044 14.2 0.6 0.16 12.4 0.1 2.1 2 0 0 2 2 2 0 LAG1, DNA binding ATG27 PF09451.5 ETO10418.1 - 0.047 12.9 0.3 0.39 9.9 0.0 2.1 2 0 0 2 2 2 0 Autophagy-related protein 27 SUR7 PF06687.7 ETO10419.1 - 0.00048 19.7 2.4 0.00068 19.2 1.6 1.2 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 ETO10419.1 - 0.0013 18.5 0.2 0.0018 18.0 0.1 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF3021 PF11457.3 ETO10419.1 - 0.028 14.2 5.1 0.047 13.5 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) Neurensin PF14927.1 ETO10419.1 - 0.039 13.3 0.0 0.089 12.1 0.0 1.6 1 0 0 1 1 1 0 Neurensin DUF2370 PF10176.4 ETO10419.1 - 0.094 12.0 0.4 1 8.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) DUF4131 PF13567.1 ETO10419.1 - 0.21 10.9 1.8 0.2 11.0 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF1625 PF07787.7 ETO10419.1 - 4.9 6.3 7.8 9.4 5.4 5.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1625) tRNA_anti-codon PF01336.20 ETO10420.1 - 0.00022 21.0 0.1 0.00056 19.7 0.1 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF106 PF01956.11 ETO10420.1 - 0.044 13.3 0.1 0.074 12.5 0.1 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF106 VIT1 PF01988.14 ETO10420.1 - 2.5 7.5 4.3 8.6 5.7 3.0 1.8 1 1 0 1 1 1 0 VIT family BLOC1_2 PF10046.4 ETO10421.1 - 0.004 17.2 5.0 0.004 17.2 3.5 6.2 5 2 1 6 6 6 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-RING_2 PF13639.1 ETO10423.1 - 0.017 14.9 6.5 0.03 14.1 4.5 1.4 1 0 0 1 1 1 0 Ring finger domain DUF4611 PF15387.1 ETO10423.1 - 0.14 12.3 14.7 0.23 11.6 3.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) FAM176 PF14851.1 ETO10423.1 - 0.43 10.2 14.4 1.3 8.7 4.6 2.2 2 0 0 2 2 2 0 FAM176 family Myc_N PF01056.13 ETO10423.1 - 0.8 8.8 13.5 1.6 7.7 4.4 2.1 2 0 0 2 2 2 0 Myc amino-terminal region PBP1_TM PF14812.1 ETO10423.1 - 0.95 9.8 12.6 4.1 7.7 4.4 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_Ag35 PF03286.9 ETO10423.1 - 1.1 8.6 23.3 0.012 15.1 6.8 2.1 1 1 1 2 2 2 0 Pox virus Ag35 surface protein Nucleoplasmin PF03066.10 ETO10423.1 - 3.8 7.0 17.4 0.32 10.5 5.5 2.3 2 0 0 2 2 2 0 Nucleoplasmin zf-C3HC4_2 PF13923.1 ETO10423.1 - 5.2 7.1 8.2 23 5.1 5.5 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) AF1Q PF15017.1 ETO10423.1 - 6.4 6.7 13.2 1.7 8.6 3.7 2.5 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator BSP_II PF05432.6 ETO10423.1 - 7.5 5.7 29.0 2 7.6 9.8 2.1 1 1 0 2 2 2 0 Bone sialoprotein II (BSP-II) RabGAP-TBC PF00566.13 ETO10424.1 - 6.8e-32 110.6 0.3 6.8e-32 110.6 0.2 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Collagen PF01391.13 ETO10424.1 - 0.03 13.8 0.9 0.066 12.7 0.6 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Secretin_N_2 PF07655.8 ETO10425.1 - 4.1 7.8 12.5 11 6.5 8.7 1.7 1 0 0 1 1 1 0 Secretin N-terminal domain Neur_chan_memb PF02932.11 ETO10425.1 - 4.2 7.1 6.7 5.4 6.8 4.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S49_N PF08496.5 ETO10427.1 - 0.0017 18.1 4.1 0.0034 17.2 2.8 1.4 1 0 0 1 1 1 1 Peptidase family S49 N-terminal BRF1 PF07741.8 ETO10427.1 - 0.14 12.3 5.3 0.31 11.2 3.7 1.5 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF4647 PF15504.1 ETO10427.1 - 0.19 10.5 7.7 0.27 10.0 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) AAA_23 PF13476.1 ETO10427.1 - 0.36 11.1 8.6 0.56 10.5 6.0 1.3 1 0 0 1 1 1 0 AAA domain DUF4175 PF13779.1 ETO10427.1 - 0.38 8.3 16.5 0.54 7.8 11.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Med15 PF09606.5 ETO10427.1 - 1.7 6.7 21.7 2.1 6.4 15.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Mem_trans PF03547.13 ETO10428.1 - 0.00034 19.0 0.2 0.00061 18.2 0.1 1.5 1 0 0 1 1 1 1 Membrane transport protein Renin_r PF07850.9 ETO10428.1 - 0.11 12.8 1.2 0.28 11.5 0.0 2.3 2 0 0 2 2 2 0 Renin receptor-like protein Peptidase_S10 PF00450.17 ETO10429.1 - 9.4e-32 110.6 0.1 1.6e-31 109.9 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase DEAD PF00270.24 ETO10430.1 - 4.8e-17 61.9 0.0 5e-17 61.8 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase CMS1 PF14617.1 ETO10430.1 - 3.7e-06 26.1 0.0 4.6e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 ETO10431.1 - 4.1e-14 52.4 0.4 5.8e-14 51.9 0.3 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.1 ETO10431.1 - 5.2e-05 22.9 0.0 7.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 ETO10431.1 - 0.00025 20.9 0.6 0.00041 20.2 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 ETO10431.1 - 0.011 15.4 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 Helicase AAA_30 PF13604.1 ETO10431.1 - 0.045 13.3 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 ETO10431.1 - 0.059 12.6 0.0 0.088 12.0 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein WD40 PF00400.27 ETO10432.1 - 1.5e-75 246.5 13.8 3.8e-12 45.5 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO10432.1 - 2.6e-10 40.3 0.4 0.00021 21.0 0.0 3.3 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO10432.1 - 1.3e-07 31.1 3.0 0.26 11.0 0.0 5.1 5 1 0 5 5 5 3 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO10432.1 - 1.2e-06 27.1 0.7 0.03 12.6 0.0 3.3 1 1 3 4 4 4 3 Cytochrome D1 heme domain Nup160 PF11715.3 ETO10432.1 - 5.9e-05 21.4 6.5 0.064 11.3 0.0 4.7 1 1 4 5 5 5 2 Nucleoporin Nup120/160 Str_synth PF03088.11 ETO10432.1 - 9.5e-05 22.3 0.0 1.2 9.1 0.0 3.1 3 0 0 3 3 3 2 Strictosidine synthase Coatomer_WDAD PF04053.9 ETO10432.1 - 0.0033 16.2 2.0 0.24 10.1 0.1 2.6 1 1 1 2 2 2 2 Coatomer WD associated region Me-amine-dh_H PF06433.6 ETO10432.1 - 0.014 14.0 0.0 0.33 9.5 0.0 2.1 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) DPPIV_N PF00930.16 ETO10432.1 - 0.015 13.9 0.1 1.2 7.7 0.0 2.9 3 0 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PQQ_2 PF13360.1 ETO10432.1 - 0.034 13.6 0.9 0.24 10.8 0.3 2.5 1 1 1 2 2 2 0 PQQ-like domain Nbas_N PF15492.1 ETO10432.1 - 0.056 12.5 1.1 4.3 6.3 0.0 3.5 2 1 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal CorC_HlyC PF03471.12 ETO10432.1 - 0.079 12.7 0.0 0.99 9.2 0.0 2.8 3 0 0 3 3 3 0 Transporter associated domain CDC37_N PF03234.9 ETO10434.1 - 0.17 12.1 7.3 0.034 14.4 2.5 1.6 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding DUF1673 PF07895.6 ETO10434.1 - 0.22 11.0 3.8 0.24 10.9 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1673) Pkinase PF00069.20 ETO10436.1 - 6.3e-55 186.1 0.1 3.5e-54 183.6 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO10436.1 - 8.1e-26 90.6 0.0 1.9e-25 89.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO10436.1 - 1.8e-05 23.8 0.0 4.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETO10436.1 - 0.00065 18.7 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETO10436.1 - 0.0016 18.2 0.4 0.027 14.1 0.1 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family PNP_UDP_1 PF01048.15 ETO10437.1 - 2e-14 53.1 0.0 1.8e-12 46.7 0.0 2.0 2 0 0 2 2 2 2 Phosphorylase superfamily Pkinase PF00069.20 ETO10438.1 - 9e-51 172.5 0.1 1.6e-50 171.7 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO10438.1 - 1.5e-23 83.1 0.5 3.7e-23 81.9 0.3 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO10438.1 - 0.00057 18.9 0.1 0.002 17.1 0.0 1.9 2 1 0 2 2 2 1 Kinase-like PIP49_C PF12260.3 ETO10438.1 - 0.0097 15.3 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Kdo PF06293.9 ETO10438.1 - 0.013 14.5 0.1 0.027 13.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO10438.1 - 0.048 13.3 0.1 0.24 11.1 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family RdRP PF05183.7 ETO10439.1 - 9.4e-79 265.6 0.6 2.6e-39 135.3 0.1 2.6 1 1 1 2 2 2 2 RNA dependent RNA polymerase 2Fe-2S_Ferredox PF11591.3 ETO10439.1 - 0.28 10.8 0.6 0.66 9.6 0.4 1.6 1 0 0 1 1 1 0 Ferredoxin chloroplastic transit peptide Mem_trans PF03547.13 ETO10440.1 - 0.19 9.9 6.1 0.2 9.9 4.2 1.0 1 0 0 1 1 1 0 Membrane transport protein DUF1510 PF07423.6 ETO10440.1 - 0.3 10.4 19.6 0.36 10.1 13.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 ETO10440.1 - 0.46 8.4 13.8 0.5 8.3 9.6 1.0 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.8 ETO10440.1 - 0.56 8.6 14.4 0.59 8.6 10.0 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2457 PF10446.4 ETO10440.1 - 0.57 8.8 17.9 0.63 8.7 12.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) GCD14 PF08704.5 ETO10440.1 - 0.8 9.1 9.6 1 8.7 6.7 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DUF1183 PF06682.7 ETO10440.1 - 0.94 9.0 9.1 1 8.9 6.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF4637 PF15470.1 ETO10440.1 - 0.94 9.0 4.1 1.2 8.7 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) FimP PF09766.4 ETO10440.1 - 1.1 8.2 18.8 1.2 8.1 13.0 1.1 1 0 0 1 1 1 0 Fms-interacting protein Vfa1 PF08432.5 ETO10440.1 - 1.3 8.9 16.5 1.6 8.6 11.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Rtf2 PF04641.7 ETO10440.1 - 1.9 7.6 15.3 2.3 7.3 10.6 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger CobT PF06213.7 ETO10440.1 - 2.1 7.3 15.1 2.3 7.2 10.5 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Daxx PF03344.10 ETO10440.1 - 2.1 6.6 16.2 2.5 6.4 11.2 1.0 1 0 0 1 1 1 0 Daxx Family Tim54 PF11711.3 ETO10440.1 - 2.6 6.5 11.2 3 6.3 7.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Pox_Ag35 PF03286.9 ETO10440.1 - 4.2 6.8 19.5 5.2 6.5 13.5 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SID-1_RNA_chan PF13965.1 ETO10440.1 - 5.3 5.0 8.0 5.1 5.1 5.5 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 NOA36 PF06524.7 ETO10440.1 - 7.9 5.6 20.8 9.2 5.4 14.4 1.0 1 0 0 1 1 1 0 NOA36 protein Macoilin PF09726.4 ETO10440.1 - 8.2 4.5 16.0 9.4 4.3 11.1 1.0 1 0 0 1 1 1 0 Transmembrane protein Striatin PF08232.7 ETO10440.1 - 8.3 6.7 12.5 12 6.2 8.7 1.3 1 0 0 1 1 1 0 Striatin family Med19 PF10278.4 ETO10440.1 - 8.3 6.0 15.3 9.1 5.9 10.6 1.0 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Hid1 PF12722.2 ETO10440.1 - 9.1 3.8 22.1 11 3.5 15.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4175 PF13779.1 ETO10440.1 - 9.4 3.7 10.1 9.9 3.7 7.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Gti1_Pac2 PF09729.4 ETO10440.1 - 9.9 5.9 13.1 15 5.4 9.1 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family PX PF00787.19 ETO10441.1 - 5.6e-17 61.5 2.4 5.6e-17 61.5 1.7 2.5 3 0 0 3 3 3 1 PX domain START PF01852.14 ETO10441.1 - 0.0013 18.1 0.0 0.031 13.5 0.0 2.3 2 0 0 2 2 2 1 START domain Ank_4 PF13637.1 ETO10442.1 - 5.9e-08 33.0 0.0 8.2e-05 23.0 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO10442.1 - 5.1e-07 29.9 0.1 5.2e-05 23.4 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO10442.1 - 7e-05 22.6 0.0 0.046 13.9 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 ETO10442.1 - 0.00042 20.4 0.0 0.018 15.2 0.0 2.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 ETO10442.1 - 0.0013 18.3 0.0 0.21 11.4 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat SprB PF13573.1 ETO10442.1 - 0.12 11.9 0.3 0.21 11.2 0.2 1.4 1 0 0 1 1 1 0 SprB repeat Ank_2 PF12796.2 ETO10443.1 - 4.3e-14 52.6 0.0 4.4e-10 39.7 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO10443.1 - 1.8e-11 43.0 0.2 0.32 11.3 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.25 ETO10443.1 - 5.1e-11 41.7 0.0 0.046 13.5 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 ETO10443.1 - 1.6e-10 41.2 0.0 0.00039 20.8 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO10443.1 - 1.2e-07 31.7 0.1 0.02 15.1 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Pkinase PF00069.20 ETO10445.1 - 1.6e-42 145.4 11.5 3.4e-25 88.6 0.3 3.9 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO10445.1 - 3.1e-18 65.7 8.2 4.6e-07 29.1 0.3 3.9 4 0 0 4 4 4 3 Protein tyrosine kinase ETRAMP PF09716.5 ETO10445.1 - 1.1 9.2 6.7 7 6.6 0.0 3.4 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) DUF4268 PF14088.1 ETO10445.1 - 1.2 8.7 9.1 2.1 8.0 1.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4268) Cpn60_TCP1 PF00118.19 ETO10446.1 - 2.7e-80 270.3 0.5 3.3e-80 270.0 0.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF751 PF05421.6 ETO10447.1 - 0.0017 18.6 1.0 0.11 12.7 0.0 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF751) DUF2628 PF10947.3 ETO10447.1 - 0.73 9.6 6.7 13 5.6 1.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2628) HORMA PF02301.13 ETO10448.1 - 3.5e-40 137.7 1.9 4.4e-40 137.3 1.3 1.0 1 0 0 1 1 1 1 HORMA domain ATG13 PF10033.4 ETO10448.1 - 0.0035 16.7 0.2 0.0048 16.3 0.1 1.2 1 0 0 1 1 1 1 Autophagy-related protein 13 CDI PF02234.14 ETO10448.1 - 0.15 11.8 0.5 2 8.2 0.0 2.7 3 0 0 3 3 3 0 Cyclin-dependent kinase inhibitor DUF2457 PF10446.4 ETO10450.1 - 0.0011 17.8 35.2 0.0011 17.8 24.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) Astro_capsid PF03115.9 ETO10450.1 - 0.0094 14.2 14.0 0.0062 14.8 5.6 2.0 2 0 0 2 2 2 1 Astrovirus capsid protein precursor TFIIA PF03153.8 ETO10450.1 - 0.53 10.1 29.3 0.061 13.2 13.5 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF1510 PF07423.6 ETO10450.1 - 1 8.7 26.9 2.3 7.5 12.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 ETO10450.1 - 2.5 6.0 24.9 0.35 8.8 11.2 2.1 2 0 0 2 2 2 0 CDC45-like protein Adaptin_binding PF10199.4 ETO10450.1 - 2.5 8.3 23.8 0.49 10.6 6.3 2.4 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Daxx PF03344.10 ETO10450.1 - 9.1 4.6 29.2 2 6.7 14.4 2.1 2 0 0 2 2 2 0 Daxx Family BUD22 PF09073.5 ETO10450.1 - 9.6 5.1 32.3 1.5 7.7 14.9 2.1 2 0 0 2 2 2 0 BUD22 AAA_18 PF13238.1 ETO10451.1 - 8.2e-23 81.1 4.0 9.2e-22 77.7 0.0 3.4 2 2 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ETO10451.1 - 1.4e-12 48.4 1.0 1.1e-11 45.6 0.0 2.4 1 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 ETO10451.1 - 1.6e-07 31.3 0.0 0.0004 20.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 ETO10451.1 - 1.3e-06 28.6 0.4 2.6e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 ETO10451.1 - 7.9e-05 22.4 0.6 0.00053 19.7 0.0 2.1 2 0 0 2 2 2 1 NTPase ADK PF00406.17 ETO10451.1 - 0.00016 21.5 0.1 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 Adenylate kinase AAA_10 PF12846.2 ETO10451.1 - 0.00043 19.8 0.0 0.016 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain AAA_28 PF13521.1 ETO10451.1 - 0.0005 20.0 0.1 0.0056 16.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 ETO10451.1 - 0.0015 17.6 0.0 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 ETO10451.1 - 0.0022 18.1 1.9 0.019 15.1 0.1 2.8 2 2 2 4 4 3 1 AAA domain RNA_helicase PF00910.17 ETO10451.1 - 0.0027 17.8 0.4 0.012 15.7 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_16 PF13191.1 ETO10451.1 - 0.0043 17.0 0.0 0.0081 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.12 ETO10451.1 - 0.0048 16.4 0.2 0.013 15.0 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MobB PF03205.9 ETO10451.1 - 0.0071 16.0 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 ETO10451.1 - 0.0077 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family SKI PF01202.17 ETO10451.1 - 0.0081 16.0 0.1 1.8 8.3 0.0 2.5 2 1 0 2 2 2 1 Shikimate kinase Thymidylate_kin PF02223.12 ETO10451.1 - 0.013 14.8 0.1 2.6 7.3 0.0 2.5 2 1 0 2 2 2 0 Thymidylate kinase AAA_3 PF07726.6 ETO10451.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 ETO10451.1 - 0.025 14.1 2.1 0.13 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 ETO10451.1 - 0.029 13.9 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF305 PF03713.8 ETO10451.1 - 0.034 13.9 1.0 0.054 13.3 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF305) NACHT PF05729.7 ETO10451.1 - 0.042 13.5 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 NACHT domain KaiC PF06745.8 ETO10451.1 - 0.05 12.7 0.3 0.21 10.6 0.0 1.9 2 0 0 2 2 2 0 KaiC DUF3808 PF10300.4 ETO10451.1 - 0.052 12.1 0.0 0.077 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) Viral_helicase1 PF01443.13 ETO10451.1 - 0.052 13.0 0.2 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 ETO10451.1 - 0.054 12.9 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 ETO10451.1 - 0.091 12.6 1.8 0.15 11.9 0.1 2.2 2 2 0 2 2 2 0 AAA domain T2SE PF00437.15 ETO10451.1 - 0.13 11.1 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein APC_CDC26 PF10471.4 ETO10451.1 - 1.6 9.5 6.5 0.85 10.4 2.8 1.8 2 0 0 2 2 1 0 Anaphase-promoting complex APC subunit 1 Sec23_trunk PF04811.10 ETO10452.1 - 0.11 11.8 0.5 0.17 11.1 0.3 1.2 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain O-antigen_lig PF13425.1 ETO10453.1 - 0.0047 16.8 0.1 0.0072 16.3 0.1 1.3 1 0 0 1 1 1 1 O-antigen ligase like membrane protein Wzy_C PF04932.10 ETO10453.1 - 0.0066 16.2 0.0 0.0095 15.7 0.0 1.3 1 0 0 1 1 1 1 O-Antigen ligase Neur_chan_memb PF02932.11 ETO10453.1 - 0.3 10.9 16.6 12 5.7 11.5 2.1 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Myc_target_1 PF15179.1 ETO10453.1 - 2.4 7.7 9.7 0.76 9.3 1.7 2.5 2 1 0 2 2 2 0 Myc target protein 1 PWWP PF00855.12 ETO10455.1 - 0.86 9.8 4.3 0.52 10.5 0.7 2.2 2 0 0 2 2 2 0 PWWP domain DUF3713 PF12506.3 ETO10455.1 - 1.3 9.1 5.8 1.1 9.3 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) PAT1 PF09770.4 ETO10456.1 - 0.032 12.5 100.1 0.0017 16.6 57.0 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 S1 PF00575.18 ETO10456.1 - 0.58 10.2 2.2 1.2 9.2 1.5 1.5 1 0 0 1 1 1 0 S1 RNA binding domain DUF964 PF06133.6 ETO10457.1 - 8 6.5 13.4 2 8.4 1.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF964) ATP-synt_ab PF00006.20 ETO10458.1 - 0.063 12.7 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF4611 PF15387.1 ETO10458.1 - 0.15 12.2 1.8 2.5 8.2 0.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4611) Ribosomal_L28 PF00830.14 ETO10459.1 - 0.021 14.6 3.7 1.1 9.1 0.2 2.4 1 1 1 2 2 2 0 Ribosomal L28 family RGS PF00615.14 ETO10460.1 - 4e-07 30.1 0.1 1.2e-06 28.6 0.1 1.8 1 1 0 1 1 1 1 Regulator of G protein signaling domain DUF1780 PF08682.5 ETO10460.1 - 0.055 12.9 0.1 0.096 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1780) Acyl-CoA_dh_N PF02771.11 ETO10461.1 - 1.9e-08 34.8 0.0 2.6e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain EF-hand_7 PF13499.1 ETO10462.1 - 0.00057 19.9 0.3 0.00057 19.9 0.2 4.1 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO10462.1 - 0.0012 17.9 0.2 0.0045 16.2 0.1 2.1 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 ETO10462.1 - 0.0022 17.7 0.3 0.015 15.1 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 ETO10462.1 - 0.014 14.6 0.7 0.039 13.3 0.1 2.2 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.1 ETO10462.1 - 0.015 14.9 0.2 0.053 13.1 0.1 2.0 1 0 0 1 1 1 0 EF-hand domain pair Striatin PF08232.7 ETO10463.1 - 0.016 15.5 15.3 0.016 15.5 10.6 4.5 1 1 2 3 3 3 0 Striatin family TMEM95 PF15203.1 ETO10463.1 - 0.11 11.8 0.3 0.26 10.6 0.2 1.6 1 0 0 1 1 1 0 TMEM95 family NPV_P10 PF05531.7 ETO10463.1 - 0.31 11.3 23.5 3.2 8.0 0.3 6.0 4 2 1 5 5 5 0 Nucleopolyhedrovirus P10 protein DASH_Dam1 PF08653.5 ETO10463.1 - 1.7 8.4 4.9 43 3.9 0.1 3.9 4 0 0 4 4 4 0 DASH complex subunit Dam1 DUF4201 PF13870.1 ETO10463.1 - 8.7 5.7 67.0 0.024 14.0 1.2 5.5 2 1 3 5 5 5 0 Domain of unknown function (DUF4201) Glypican PF01153.14 ETO10464.1 - 0.0082 14.8 3.4 0.0094 14.6 2.3 1.1 1 0 0 1 1 1 1 Glypican Pex14_N PF04695.8 ETO10464.1 - 0.12 12.3 1.2 0.18 11.8 0.9 1.4 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CDC45 PF02724.9 ETO10464.1 - 0.2 9.6 5.5 0.23 9.4 3.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.5 ETO10464.1 - 0.34 10.8 6.9 0.48 10.4 4.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop14 PF04147.7 ETO10464.1 - 1.5 6.6 10.6 1.9 6.2 7.3 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4175 PF13779.1 ETO10464.1 - 2.9 5.4 5.9 3.5 5.2 4.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CobT PF06213.7 ETO10464.1 - 6.4 5.8 11.3 8.4 5.4 7.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF3081 PF11280.3 ETO10465.1 - 0.076 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3081) SoxE PF06525.6 ETO10466.1 - 0.32 10.2 5.1 0.43 9.8 2.7 1.8 1 1 0 1 1 1 0 Sulfocyanin (SoxE) Daxx PF03344.10 ETO10466.1 - 0.57 8.6 34.0 0.005 15.4 17.0 1.9 2 0 0 2 2 2 0 Daxx Family Pkinase PF00069.20 ETO10467.1 - 2e-44 151.7 4.2 1.9e-30 105.8 0.0 2.9 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO10467.1 - 1.1e-16 60.6 0.1 2.2e-11 43.3 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase cNMP_binding PF00027.24 ETO10467.1 - 5.3e-12 45.3 0.0 3.4e-08 33.1 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Gly-zipper_Omp PF13488.1 ETO10468.1 - 3e-12 45.9 156.6 0.55 9.9 6.9 9.0 2 1 3 5 5 5 4 Glycine zipper Gly-zipper_YMGG PF13441.1 ETO10468.1 - 0.0032 16.9 145.3 1.5e+04 -104.1 100.7 9.1 1 1 0 1 1 1 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.10 ETO10468.1 - 1.2 8.8 172.4 0.3 10.7 23.1 10.3 3 2 4 7 7 7 0 Glycine zipper 2TM domain Peptidase_M90 PF06167.7 ETO10470.1 - 0.38 10.1 3.4 0.17 11.2 0.2 2.0 3 0 0 3 3 3 0 Glucose-regulated metallo-peptidase M90 Tubulin PF00091.20 ETO10472.1 - 1.1e-38 133.2 0.0 1.4e-38 132.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.1 ETO10472.1 - 0.00046 19.6 0.0 0.0028 17.1 0.0 1.9 2 0 0 2 2 2 1 Tubulin domain Tubulin_C PF03953.12 ETO10472.1 - 0.00047 20.1 0.3 0.0015 18.5 0.1 1.9 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_2 PF13809.1 ETO10472.1 - 0.14 11.0 0.7 0.18 10.7 0.0 1.5 2 0 0 2 2 2 0 Tubulin like Tubulin_C PF03953.12 ETO10473.1 - 1.1e-31 109.4 0.3 1.5e-31 109.0 0.2 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain ADIP PF11559.3 ETO10474.1 - 0.029 14.2 3.1 0.033 14.1 1.7 1.3 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding ATP11 PF06644.6 ETO10475.1 - 0.047 13.1 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 ATP11 protein DUF3093 PF11292.3 ETO10476.1 - 0.066 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) OEP PF02321.13 ETO10476.1 - 6.4 6.3 12.7 0.26 10.8 4.6 1.7 2 0 0 2 2 2 0 Outer membrane efflux protein XK-related PF09815.4 ETO10478.1 - 7.1e-07 28.5 5.9 8e-07 28.3 4.1 1.1 1 0 0 1 1 1 1 XK-related protein PDR_assoc PF08370.6 ETO10478.1 - 0.93 9.0 4.1 0.39 10.2 0.9 1.9 2 1 0 2 2 2 0 Plant PDR ABC transporter associated IPK PF03770.11 ETO10479.1 - 0.011 15.3 0.2 0.016 14.8 0.1 1.2 1 0 0 1 1 1 0 Inositol polyphosphate kinase NVEALA PF14055.1 ETO10479.1 - 0.54 10.0 0.0 0.54 10.0 0.0 3.2 4 0 0 4 4 4 0 NVEALA protein Ion_trans_N PF08412.5 ETO10479.1 - 1.2 8.5 5.8 3.7 6.9 0.5 2.7 2 1 0 2 2 2 0 Ion transport protein N-terminal FF PF01846.14 ETO10481.1 - 1.3e-11 44.2 9.4 1.8e-05 24.5 0.1 3.9 2 1 2 4 4 4 2 FF domain DUF2150 PF09920.4 ETO10481.1 - 0.043 13.4 1.4 0.044 13.3 0.1 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) DUF3983 PF13137.1 ETO10481.1 - 1 9.0 5.3 1.1 8.9 0.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3983) Med21 PF11221.3 ETO10481.1 - 7.1 6.6 10.3 1.5 8.8 1.5 2.2 2 0 0 2 2 2 0 Subunit 21 of Mediator complex ATP-synt_E PF05680.7 ETO10481.1 - 7.6 6.5 12.5 0.078 12.9 1.6 2.5 3 0 0 3 3 3 0 ATP synthase E chain NACHT PF05729.7 ETO10483.1 - 2.9e-20 72.5 0.0 4.9e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETO10483.1 - 9.3e-06 25.8 0.7 0.00045 20.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 ETO10483.1 - 3.4e-05 22.8 0.1 0.0001 21.2 0.1 1.8 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 ETO10483.1 - 0.0019 18.2 0.3 0.016 15.1 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain Torsin PF06309.6 ETO10483.1 - 0.0087 15.9 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 Torsin RNA_helicase PF00910.17 ETO10483.1 - 0.0098 16.0 0.5 1.2 9.3 0.0 3.6 2 1 1 3 3 3 1 RNA helicase AAA_19 PF13245.1 ETO10483.1 - 0.012 15.3 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain PhoH PF02562.11 ETO10483.1 - 0.018 14.2 0.0 2.5 7.2 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_5 PF07728.9 ETO10483.1 - 0.018 14.7 0.1 0.35 10.5 0.1 2.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 ETO10483.1 - 0.13 13.1 4.6 0.54 11.0 0.3 3.2 1 1 1 2 2 2 0 AAA domain G6PD_C PF02781.11 ETO10484.1 - 5.2e-72 242.1 0.0 7.1e-72 241.7 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 ETO10484.1 - 2.5e-47 161.4 2.3 2.6e-46 158.1 1.6 2.2 1 1 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF4460 PF14687.1 ETO10484.1 - 0.072 12.8 1.1 4 7.2 0.2 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4460) DUF3139 PF11337.3 ETO10484.1 - 3 8.1 5.3 3.8 7.8 0.1 3.4 3 1 0 4 4 4 0 Protein of unknown function (DUF3139) WD40 PF00400.27 ETO10485.1 - 2.7e-61 201.4 21.8 6.2e-11 41.7 0.3 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO10485.1 - 7.4e-18 63.9 9.8 0.0011 17.1 0.0 6.0 1 1 4 6 6 6 6 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO10485.1 - 4.3e-05 22.4 17.5 0.0033 16.2 2.0 4.1 1 1 1 2 2 2 2 Nup133 N terminal like HAD PF12710.2 ETO10485.1 - 0.62 10.2 5.0 8 6.5 0.0 3.4 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF2559 PF10832.3 ETO10485.1 - 2.8 7.8 0.0 2.8 7.8 0.0 3.4 5 0 0 5 5 5 0 Protein of unknown function (DUF2559) DUF2651 PF10852.3 ETO10486.1 - 0.78 10.1 5.1 0.26 11.6 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2651) Ubiq_cyt_C_chap PF03981.7 ETO10487.1 - 1.3e-08 34.8 0.0 2.6e-08 33.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquinol-cytochrome C chaperone DUF3671 PF12420.3 ETO10487.1 - 0.0011 18.9 0.3 0.0041 17.0 0.2 2.0 1 0 0 1 1 1 1 Protein of unknown function TPR_12 PF13424.1 ETO10488.1 - 2.8e-32 110.4 7.6 1.2e-15 57.1 0.3 3.2 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO10488.1 - 1.2e-15 56.0 14.8 4.4e-06 26.0 0.4 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO10488.1 - 1e-13 50.0 7.9 3.3e-05 23.4 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO10488.1 - 5.3e-12 45.2 6.9 2.2e-07 30.3 0.2 3.2 2 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETO10488.1 - 6e-12 44.6 18.6 1.2e-05 24.6 0.2 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO10488.1 - 2.4e-11 42.5 4.6 0.00011 21.7 0.0 4.5 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO10488.1 - 1.5e-08 34.2 0.0 0.0033 17.3 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO10488.1 - 1.2e-05 25.0 3.6 0.05 13.8 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat MIT PF04212.13 ETO10488.1 - 3.4e-05 23.6 3.8 0.006 16.4 0.1 3.9 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 ETO10488.1 - 0.0011 19.2 1.5 7.9 7.1 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF1828 PF08861.5 ETO10488.1 - 0.021 14.4 0.5 0.096 12.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF1828 CRA PF06589.6 ETO10488.1 - 0.065 12.5 2.1 0.15 11.3 1.5 1.5 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) SHNi-TPR PF10516.4 ETO10488.1 - 0.073 12.3 0.0 15 4.8 0.0 2.6 2 0 0 2 2 2 0 SHNi-TPR TPR_3 PF07720.7 ETO10488.1 - 0.23 11.3 11.3 0.48 10.2 0.4 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat LINES_N PF14694.1 ETO10490.1 - 1e-10 41.4 0.5 1e-10 41.4 0.3 1.9 2 0 0 2 2 2 1 Lines N-terminus LINES_C PF14695.1 ETO10490.1 - 5.6e-07 28.6 0.3 1.6e-06 27.2 0.2 1.8 1 0 0 1 1 1 1 Lines C-terminus MIP-T3 PF10243.4 ETO10490.1 - 0.00038 19.0 30.7 0.00038 19.0 21.3 2.1 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 DUF3584 PF12128.3 ETO10491.1 - 0.4 7.9 15.5 0.52 7.5 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Band_3_cyto PF07565.8 ETO10491.1 - 0.86 9.0 6.1 0.14 11.6 2.1 1.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DDHD PF02862.12 ETO10491.1 - 8.5 6.1 10.2 3.4 7.4 5.3 1.5 2 0 0 2 2 2 0 DDHD domain DUF805 PF05656.9 ETO10493.1 - 9.5 6.0 7.6 86 2.9 4.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Pkinase PF00069.20 ETO10495.1 - 6.8e-09 35.2 1.0 8.3e-09 34.9 0.7 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO10495.1 - 0.0015 17.6 0.6 0.0018 17.4 0.4 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO10495.1 - 0.026 13.4 0.0 0.03 13.2 0.0 1.1 1 0 0 1 1 1 0 Kinase-like TerB-N PF13208.1 ETO10495.1 - 0.051 13.0 0.5 0.054 12.9 0.4 1.1 1 0 0 1 1 1 0 TerB-N Myotub-related PF06602.9 ETO10496.1 - 1.7e-89 300.0 1.6 2.3e-89 299.6 1.1 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 ETO10496.1 - 0.00034 20.0 0.1 0.00063 19.1 0.1 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 ETO10496.1 - 0.00067 19.9 0.0 0.0013 19.0 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 ETO10496.1 - 0.0028 17.2 0.3 0.0082 15.7 0.2 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Sec7_N PF12783.2 ETO10496.1 - 0.05 13.0 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal YycC PF14174.1 ETO10496.1 - 0.073 12.7 0.3 1.8 8.2 0.1 2.5 2 0 0 2 2 2 0 YycC-like protein Ras PF00071.17 ETO10497.1 - 1.9e-50 170.3 0.1 2.6e-50 169.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO10497.1 - 2.4e-18 66.7 0.0 1e-16 61.4 0.0 2.2 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO10497.1 - 1.9e-13 49.9 0.0 2.6e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO10497.1 - 0.0001 21.7 0.0 0.00019 20.9 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 ETO10497.1 - 0.00019 21.3 0.0 0.00043 20.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 ETO10497.1 - 0.0061 15.7 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MobB PF03205.9 ETO10497.1 - 0.056 13.1 0.0 0.18 11.4 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B WD40 PF00400.27 ETO10498.1 - 3.7e-60 197.8 23.5 1.4e-12 46.9 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO10498.1 - 5.3e-12 44.6 6.4 0.026 12.7 0.1 5.8 1 1 3 6 6 6 6 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO10498.1 - 0.0019 17.9 2.0 0.41 10.4 0.0 4.3 4 2 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Vps53_N PF04100.7 ETO10501.1 - 4.5e-05 22.3 3.3 0.00012 21.0 2.3 1.6 1 1 0 1 1 1 1 Vps53-like, N-terminal Herpes_LMP1 PF05297.6 ETO10501.1 - 0.4 9.5 3.4 0.54 9.1 2.4 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF946 PF06101.6 ETO10502.1 - 5.3e-06 24.7 0.0 0.029 12.3 0.0 2.2 2 0 0 2 2 2 2 Plant protein of unknown function (DUF946) DUF2457 PF10446.4 ETO10503.1 - 0.004 15.9 9.8 0.006 15.3 6.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) NOA36 PF06524.7 ETO10503.1 - 0.042 13.1 9.5 0.06 12.6 6.6 1.2 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.1 ETO10503.1 - 0.8 9.3 5.3 0.9 9.2 3.1 1.6 1 1 0 1 1 1 0 FAM176 family CDC45 PF02724.9 ETO10503.1 - 1.3 6.9 9.2 1.6 6.6 6.4 1.2 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.6 ETO10503.1 - 1.7 8.4 12.6 4.1 7.1 8.7 1.7 1 1 0 1 1 1 0 RXT2-like, N-terminal 2OG-FeII_Oxy PF03171.15 ETO10504.1 - 1.2e-10 41.5 0.1 2.9e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 ETO10504.1 - 1.1e-07 32.3 0.2 2.9e-07 30.9 0.1 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 ETO10504.1 - 5.6e-06 25.8 0.2 1.4e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily CAF-1_p150 PF11600.3 ETO10504.1 - 0.38 10.0 6.1 0.61 9.4 4.2 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1041 PF06292.12 ETO10506.1 - 1.4 9.1 4.2 1.1 9.4 1.3 1.9 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1041) RepB-RCR_reg PF10723.4 ETO10507.1 - 0.038 13.7 0.1 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 Replication regulatory protein RepB Aldolase_2 PF10120.4 ETO10507.1 - 0.046 13.0 0.0 0.073 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative aldolase PI3_PI4_kinase PF00454.22 ETO10508.1 - 3.9e-28 98.5 0.8 4.2e-14 52.6 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase Rep_fac_C PF08542.6 ETO10509.1 - 1.2e-08 34.8 0.5 2.1e-08 34.0 0.1 1.5 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 ETO10509.1 - 0.0048 16.5 0.7 0.031 13.9 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.10 ETO10509.1 - 0.037 12.7 0.6 0.048 12.3 0.1 1.5 1 1 1 2 2 2 0 Rad17 cell cycle checkpoint protein WD40 PF00400.27 ETO10510.1 - 2e-09 36.9 3.2 0.0015 18.2 0.0 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.6 ETO10510.1 - 6.5e-05 22.7 4.6 0.43 10.2 0.0 3.6 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO10510.1 - 0.00071 19.1 1.6 7 6.4 0.0 5.0 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 ETO10510.1 - 0.021 13.9 0.0 10 5.1 0.0 3.1 2 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal F-box-like PF12937.2 ETO10511.1 - 1e-05 25.1 0.1 1.8e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETO10511.1 - 9.7e-05 21.9 0.2 0.00017 21.1 0.1 1.4 1 0 0 1 1 1 1 F-box domain SWIRM PF04433.12 ETO10511.1 - 0.69 10.0 5.0 1.3 9.1 1.1 2.5 1 1 1 2 2 2 0 SWIRM domain Zip PF02535.17 ETO10513.1 - 0.55 9.1 6.5 0.66 8.9 4.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter YqfQ PF14181.1 ETO10513.1 - 0.9 9.5 8.3 1.6 8.7 5.7 1.4 1 0 0 1 1 1 0 YqfQ-like protein RNA_polI_A34 PF08208.6 ETO10513.1 - 2.6 7.6 15.9 4.4 6.9 11.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 zf-C2H2 PF00096.21 ETO10514.1 - 4.7e-11 42.3 20.8 0.0011 19.1 0.6 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETO10514.1 - 5.1e-08 32.6 26.1 0.00093 19.3 0.4 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETO10514.1 - 0.034 14.4 15.8 0.68 10.3 0.3 4.5 4 0 0 4 4 4 0 Zinc-finger double domain zf-BED PF02892.10 ETO10514.1 - 0.091 12.5 14.6 0.13 12.0 0.9 3.9 2 2 1 3 3 3 0 BED zinc finger C1_4 PF07975.7 ETO10514.1 - 0.31 11.0 13.1 0.36 10.8 2.8 3.3 1 1 2 3 3 3 0 TFIIH C1-like domain PHD PF00628.24 ETO10514.1 - 1.4 8.6 11.5 0.25 11.0 4.5 2.3 2 0 0 2 2 2 0 PHD-finger GATase PF00117.23 ETO10515.1 - 2.1e-33 115.4 0.0 4.6e-33 114.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 ETO10515.1 - 4.7e-18 64.6 0.0 1e-16 60.3 0.0 2.6 2 0 0 2 2 2 1 GMP synthase C terminal domain Peptidase_C26 PF07722.8 ETO10515.1 - 1.3e-08 34.5 0.1 1.2e-06 28.0 0.0 3.0 1 1 0 1 1 1 1 Peptidase C26 Asn_synthase PF00733.16 ETO10515.1 - 1.4e-05 24.7 0.0 2.9e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.12 ETO10515.1 - 4.3e-05 22.5 0.0 0.014 14.3 0.0 2.7 2 0 0 2 2 2 2 NAD synthase tRNA_Me_trans PF03054.11 ETO10515.1 - 0.00011 20.9 0.1 0.00039 19.0 0.0 1.8 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.8 ETO10515.1 - 0.0064 15.8 1.2 1.4 8.1 0.8 3.4 2 1 0 2 2 2 1 Queuosine biosynthesis protein QueC GATase_3 PF07685.9 ETO10515.1 - 0.0072 15.9 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain ThiI PF02568.9 ETO10515.1 - 0.02 14.3 0.7 0.11 11.9 0.0 2.3 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.14 ETO10515.1 - 0.034 13.9 0.0 0.098 12.4 0.0 1.8 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Ketoacyl-synt_C PF02801.17 ETO10515.1 - 0.047 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain Prp18 PF02840.10 ETO10516.1 - 3.5e-35 120.9 0.3 3.5e-35 120.9 0.2 3.1 3 1 0 3 3 3 1 Prp18 domain PRP4 PF08799.6 ETO10516.1 - 7.7e-12 44.2 7.0 7.7e-12 44.2 4.9 2.3 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like DUF288 PF03385.12 ETO10516.1 - 0.025 13.0 0.4 3.5 5.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF288 Pro_isomerase PF00160.16 ETO10517.1 - 3.3e-47 160.5 0.2 9.7e-47 159.0 0.2 1.8 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K_channel_TID PF07941.6 ETO10519.1 - 1.6 8.9 5.1 9.4 6.5 0.2 2.6 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain WD40 PF00400.27 ETO10520.1 - 1.4e-54 180.0 24.3 1.2e-10 40.8 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO10520.1 - 1.1e-07 30.4 6.8 0.033 12.3 0.0 5.1 2 2 3 6 6 6 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO10520.1 - 0.00067 18.5 10.0 0.071 11.8 1.7 3.3 2 2 1 3 3 3 2 Nup133 N terminal like WD40 PF00400.27 ETO10521.1 - 1.7e-64 211.5 16.6 2e-11 43.2 0.1 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO10521.1 - 3.2e-11 42.0 7.4 0.011 13.9 0.0 5.9 2 1 3 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO10521.1 - 0.00056 18.7 11.4 0.066 11.9 3.8 3.7 2 1 2 4 4 4 3 Nup133 N terminal like DUF2963 PF11178.3 ETO10521.1 - 1.4 8.4 4.4 1.4 8.3 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2963) DUF3816 PF12822.2 ETO10522.1 - 0.097 12.5 10.4 0.38 10.6 7.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) ABC2_membrane_3 PF12698.2 ETO10522.1 - 1.1 8.1 18.5 0.82 8.6 10.6 1.8 1 1 2 3 3 3 0 ABC-2 family transporter protein PDEase_I PF00233.14 ETO10523.1 - 9.5e-26 90.9 0.5 1.2e-24 87.3 0.3 2.2 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF3357 PF11837.3 ETO10523.1 - 0.046 13.5 0.4 0.94 9.3 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) FKS1_dom1 PF14288.1 ETO10523.1 - 0.23 11.3 5.3 0.11 12.4 0.5 2.4 2 1 1 3 3 3 0 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF2951 PF11166.3 ETO10523.1 - 0.37 10.6 5.4 0.87 9.4 1.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Myf5 PF12232.3 ETO10523.1 - 0.58 10.8 3.2 3.7 8.2 0.0 2.6 2 0 0 2 2 2 0 Myogenic determination factor 5 Myotub-related PF06602.9 ETO10524.1 - 1e-124 415.8 1.1 1.5e-124 415.3 0.8 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 ETO10524.1 - 0.0026 17.1 0.1 0.0071 15.7 0.1 1.7 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 ETO10524.1 - 0.016 15.4 0.0 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.15 ETO10524.1 - 0.025 14.1 0.1 0.065 12.8 0.0 1.7 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF2356 PF10189.4 ETO10526.1 - 0.11 11.4 0.1 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Conserved protein (DUF2356) CAP_GLY PF01302.20 ETO10527.1 - 9.1e-06 25.2 0.1 2.5e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 CAP-Gly domain EF-hand_1 PF00036.27 ETO10527.1 - 0.012 14.9 0.2 0.025 13.8 0.2 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 ETO10527.1 - 0.023 14.5 0.5 0.053 13.4 0.3 1.6 1 0 0 1 1 1 0 EF-hand domain UPF0118 PF01594.11 ETO10528.1 - 0.69 8.8 2.5 0.53 9.2 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF20 DSBA PF01323.15 ETO10531.1 - 1.9e-19 70.0 0.0 4e-16 59.1 0.0 2.1 2 0 0 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 ETO10531.1 - 0.034 14.1 0.0 0.33 10.9 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin Herpes_LMP1 PF05297.6 ETO10532.1 - 0.14 11.0 6.3 0.16 10.8 4.4 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) NOA36 PF06524.7 ETO10532.1 - 1.3 8.2 9.3 1.7 7.8 6.4 1.1 1 0 0 1 1 1 0 NOA36 protein Secretin_N_2 PF07655.8 ETO10532.1 - 7.2 7.0 8.6 12 6.4 6.0 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain Cas_DxTHG PF09455.5 ETO10533.1 - 0.03 13.4 1.9 0.04 13.0 1.3 1.2 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Caudo_TAP PF02413.12 ETO10533.1 - 0.05 13.7 1.8 0.064 13.4 1.3 1.2 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein Imm20 PF15568.1 ETO10533.1 - 0.082 12.8 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 20 NTP_transf_4 PF13562.1 ETO10533.1 - 0.11 12.1 0.1 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Sugar nucleotidyl transferase Cupin_4 PF08007.7 ETO10533.1 - 0.13 11.4 0.8 0.15 11.3 0.5 1.0 1 0 0 1 1 1 0 Cupin superfamily protein DUF4407 PF14362.1 ETO10533.1 - 0.46 9.3 6.9 0.46 9.3 4.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Neur_chan_memb PF02932.11 ETO10533.1 - 1.4 8.7 7.6 1.5 8.6 5.3 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4061 PF13270.1 ETO10533.1 - 2.8 8.1 5.7 0.35 10.9 0.8 1.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4061) Pex24p PF06398.6 ETO10534.1 - 0.0026 16.6 5.6 0.18 10.5 2.1 2.8 1 1 1 2 2 2 2 Integral peroxisomal membrane peroxin SID-1_RNA_chan PF13965.1 ETO10535.1 - 0.98 7.5 4.2 1.8 6.6 2.9 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Kelch_2 PF07646.10 ETO10536.1 - 3.3e-06 26.6 5.0 0.031 14.0 0.1 4.7 5 1 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 ETO10536.1 - 5e-05 22.7 0.4 1.4 8.5 0.0 4.4 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 ETO10536.1 - 0.0097 15.8 3.6 1.6 8.7 0.0 4.0 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.1 ETO10536.1 - 0.023 14.8 0.3 1.4 9.1 0.0 3.8 5 0 0 5 5 5 0 Galactose oxidase, central domain Tim54 PF11711.3 ETO10539.1 - 0.03 12.9 1.8 0.046 12.3 1.2 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Pex14_N PF04695.8 ETO10539.1 - 0.099 12.6 4.6 0.21 11.6 3.2 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Menin PF05053.8 ETO10539.1 - 0.84 7.7 8.1 1 7.4 5.6 1.1 1 0 0 1 1 1 0 Menin Zip PF02535.17 ETO10539.1 - 3.7 6.4 5.2 11 4.9 3.6 1.7 1 1 0 1 1 1 0 ZIP Zinc transporter RP-C_C PF11800.3 ETO10539.1 - 9.5 5.8 7.3 17 5.0 5.0 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region WD40 PF00400.27 ETO10540.1 - 2.1e-23 81.2 8.3 3.5e-10 39.3 0.1 4.3 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO10540.1 - 0.012 13.7 0.6 0.43 8.6 0.1 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 HAD PF12710.2 ETO10540.1 - 0.12 12.4 0.1 0.61 10.2 0.0 1.9 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase WD40 PF00400.27 ETO10541.1 - 0.00013 21.6 0.5 0.0015 18.3 0.4 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat NMT PF01233.14 ETO10543.1 - 0.1 12.2 0.2 0.18 11.4 0.1 1.4 1 1 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Flavodoxin_3 PF12641.2 ETO10543.1 - 0.11 11.9 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Flavodoxin domain Ribonuc_red_sm PF00268.16 ETO10544.1 - 0.029 13.3 0.3 0.032 13.2 0.2 1.1 1 0 0 1 1 1 0 Ribonucleotide reductase, small chain DUF3464 PF11947.3 ETO10544.1 - 0.029 13.8 0.0 0.034 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) EIIBC-GUT_N PF03612.9 ETO10544.1 - 0.08 12.5 0.4 0.099 12.2 0.3 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus FTHFS PF01268.14 ETO10544.1 - 0.11 10.4 0.1 0.15 10.0 0.1 1.2 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase PYC_OADA PF02436.13 ETO10544.1 - 0.19 11.1 0.7 0.23 10.8 0.5 1.2 1 0 0 1 1 1 0 Conserved carboxylase domain DUF4582 PF15189.1 ETO10545.1 - 0.043 13.0 0.2 0.11 11.6 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4582) Sua5_yciO_yrdC PF01300.13 ETO10545.1 - 0.091 12.0 0.1 0.17 11.0 0.1 1.4 1 0 0 1 1 1 0 Telomere recombination zf-CCHH PF10283.4 ETO10546.1 - 2.2e-11 43.3 1.0 5.3e-11 42.1 0.7 1.7 1 0 0 1 1 1 1 Zinc-finger (CX5CX6HX5H) motif DUF1298 PF06974.8 ETO10547.1 - 2.7e-06 27.2 0.0 3.6e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) Gar1 PF04410.9 ETO10549.1 - 9e-13 47.9 5.1 1.2e-11 44.3 0.2 2.9 2 1 0 2 2 2 2 Gar1/Naf1 RNA binding region DUF4329 PF14220.1 ETO10549.1 - 0.79 9.6 6.6 0.3 11.0 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4329) XisI PF08869.6 ETO10550.1 - 0.068 13.2 2.7 0.093 12.8 0.4 2.1 2 0 0 2 2 2 0 XisI protein DUF2815 PF10991.3 ETO10551.1 - 0.62 9.5 5.6 0.13 11.8 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2815) ATP-synt PF00231.14 ETO10552.1 - 2e-08 33.9 0.5 2.6e-08 33.5 0.4 1.1 1 0 0 1 1 1 1 ATP synthase SPC12 PF06645.8 ETO10552.1 - 0.016 14.9 0.1 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DuffyBP_N PF12377.3 ETO10552.1 - 0.036 14.2 0.0 0.055 13.6 0.0 1.2 1 0 0 1 1 1 0 Duffy binding protein N terminal ATP-synt PF00231.14 ETO10553.1 - 2.8e-07 30.2 0.0 9.8e-07 28.4 0.0 1.7 1 1 0 1 1 1 1 ATP synthase DUF3915 PF13054.1 ETO10553.1 - 0.02 14.8 0.3 2.9 7.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Peptidase_C3 PF00548.15 ETO10553.1 - 0.11 12.2 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) TPR_12 PF13424.1 ETO10554.1 - 2.8e-68 225.8 3.0 3.3e-23 81.4 0.1 5.1 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.23 ETO10554.1 - 5.2e-42 139.7 26.4 2.2e-07 30.1 0.4 8.2 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.1 ETO10554.1 - 2e-38 129.8 7.0 6.7e-13 48.0 1.1 5.5 4 1 0 5 5 5 4 TPR repeat TPR_2 PF07719.12 ETO10554.1 - 1.1e-37 124.8 15.5 3e-06 26.7 0.4 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETO10554.1 - 4.2e-37 123.1 26.2 1.2e-06 27.8 1.2 6.7 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_7 PF13176.1 ETO10554.1 - 5.6e-35 116.3 7.3 5e-05 22.7 0.0 7.9 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_10 PF13374.1 ETO10554.1 - 1.4e-33 113.8 0.6 1.3e-05 24.9 0.0 7.7 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.1 ETO10554.1 - 2.1e-18 64.9 4.7 0.0026 17.8 0.1 8.2 8 2 0 8 8 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO10554.1 - 6.3e-18 64.9 0.2 1.3e-05 25.7 0.1 5.5 3 2 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO10554.1 - 2.5e-16 58.6 0.0 0.031 14.9 0.0 7.5 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO10554.1 - 3.3e-14 52.2 0.2 0.064 13.7 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat SNAP PF14938.1 ETO10554.1 - 2e-12 46.8 0.4 0.00023 20.4 0.1 3.2 3 0 0 3 3 3 2 Soluble NSF attachment protein, SNAP TPR_19 PF14559.1 ETO10554.1 - 1.2e-09 38.3 0.3 0.0057 16.9 0.1 4.7 4 1 1 5 5 5 3 Tetratricopeptide repeat MIT PF04212.13 ETO10554.1 - 7.3e-09 35.3 16.7 0.15 11.9 0.9 6.2 5 1 1 6 6 6 4 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 ETO10554.1 - 1.1e-07 31.8 9.6 0.16 12.0 0.7 5.1 2 2 3 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 ETO10554.1 - 5.1e-06 25.6 0.1 4.2 6.6 0.0 5.4 5 0 0 5 5 5 1 SHNi-TPR DUF2225 PF09986.4 ETO10554.1 - 2e-05 24.1 5.9 0.12 11.7 0.4 4.0 1 1 3 4 4 4 2 Uncharacterized protein conserved in bacteria (DUF2225) RPN7 PF10602.4 ETO10554.1 - 3e-05 23.4 10.4 0.39 10.0 0.0 6.1 3 2 3 6 6 6 1 26S proteasome subunit RPN7 TPR_3 PF07720.7 ETO10554.1 - 0.00019 21.1 10.0 2.1 8.2 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat DUF627 PF04781.7 ETO10554.1 - 0.00037 20.0 0.4 3.4 7.3 0.0 4.8 3 2 3 6 6 6 1 Protein of unknown function (DUF627) TPR_21 PF09976.4 ETO10554.1 - 0.0019 18.1 4.9 0.62 9.9 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat Sel1 PF08238.7 ETO10554.1 - 0.003 18.1 7.5 14 6.5 0.1 6.1 7 0 0 7 7 6 0 Sel1 repeat PPR PF01535.15 ETO10554.1 - 0.014 15.2 10.7 1.8 8.7 0.0 6.2 7 0 0 7 7 6 0 PPR repeat BTAD PF03704.12 ETO10554.1 - 0.048 13.9 0.0 6.5 7.0 0.0 3.0 2 1 1 3 3 3 0 Bacterial transcriptional activator domain Vps39_1 PF10366.4 ETO10554.1 - 0.1 12.5 0.7 0.79 9.7 0.0 2.6 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 TOM20_plant PF06552.7 ETO10554.1 - 0.15 11.6 5.5 8.1 5.9 0.0 4.2 3 1 1 5 5 5 0 Plant specific mitochondrial import receptor subunit TOM20 Sec5 PF15469.1 ETO10554.1 - 0.48 10.1 7.8 3.5 7.3 1.0 3.6 2 1 2 4 4 4 0 Exocyst complex component Sec5 Abhydrolase_6 PF12697.2 ETO10555.1 - 1.5e-18 67.5 0.0 2.9e-18 66.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETO10555.1 - 2.5e-08 33.7 0.0 6.5e-07 29.1 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETO10555.1 - 0.00016 21.4 0.0 0.00069 19.3 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 ETO10555.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein adh_short_C2 PF13561.1 ETO10556.1 - 1.1e-23 84.2 0.0 5.3e-23 82.0 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETO10556.1 - 8e-10 38.8 0.1 1.5e-05 24.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase DUF607 PF04678.8 ETO10558.1 - 0.11 12.3 0.2 0.12 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF607 bZIP_Maf PF03131.12 ETO10558.1 - 0.19 12.0 4.5 0.23 11.7 2.8 1.3 1 1 0 1 1 1 0 bZIP Maf transcription factor DUF1664 PF07889.7 ETO10558.1 - 2.5 7.9 6.0 0.37 10.5 1.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) IncA PF04156.9 ETO10558.1 - 3.5 7.1 9.4 6.6 6.2 6.5 1.5 1 1 0 1 1 1 0 IncA protein tRNA_int_end_N2 PF12928.2 ETO10559.1 - 0.0023 17.3 0.0 0.0059 16.0 0.0 1.7 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term DUF2288 PF10052.4 ETO10559.1 - 0.07 12.8 0.1 0.75 9.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2288) WD40 PF00400.27 ETO10560.1 - 6.4e-06 25.8 8.6 2.5e-05 23.9 0.1 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Pyridox_ox_2 PF12900.2 ETO10561.1 - 2.1e-18 66.5 0.0 2.8e-17 62.8 0.0 2.1 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase ATG27 PF09451.5 ETO10561.1 - 0.033 13.4 0.1 0.056 12.6 0.0 1.4 1 0 0 1 1 1 0 Autophagy-related protein 27 Baculo_PEP_C PF04513.7 ETO10562.1 - 0.052 13.3 1.2 0.11 12.3 0.8 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1759 PF03564.10 ETO10562.1 - 0.15 11.8 4.5 0.089 12.5 1.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1759) CDC45 PF02724.9 ETO10562.1 - 0.91 7.4 34.6 1.9 6.4 1.0 2.4 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.7 ETO10562.1 - 1.4 6.7 33.4 0.04 11.8 17.7 1.9 2 0 0 2 2 2 0 Nop14-like family NPV_P10 PF05531.7 ETO10562.1 - 1.5 9.1 7.0 12 6.2 2.5 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Zip PF02535.17 ETO10562.1 - 3.2 6.6 4.5 4.9 6.0 3.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter fn3 PF00041.16 ETO10563.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Fibronectin type III domain TLD PF07534.11 ETO10564.1 - 1.4e-09 38.0 1.0 2.4e-09 37.2 0.7 1.4 1 1 0 1 1 1 1 TLD SMN PF06003.7 ETO10564.1 - 0.012 14.7 0.2 0.016 14.3 0.2 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) PEP_mutase PF13714.1 ETO10565.1 - 2.8e-65 219.8 0.0 3.5e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 ETO10565.1 - 0.027 12.6 0.0 0.059 11.5 0.0 1.5 1 1 0 1 1 1 0 Isocitrate lyase family Ala_racemase_N PF01168.15 ETO10566.1 - 4.5e-07 29.6 0.0 6.7e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DUF3767 PF12597.3 ETO10566.1 - 0.055 13.1 0.3 9.9 5.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3767) ZZ PF00569.12 ETO10567.1 - 2.5e-13 49.3 15.0 5.2e-12 45.1 2.6 2.7 2 0 0 2 2 2 2 Zinc finger, ZZ type MIP-T3 PF10243.4 ETO10567.1 - 0.0016 17.0 21.1 0.0016 17.0 14.6 2.3 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 YhjQ PF06564.7 ETO10568.1 - 0.12 11.6 1.9 0.6 9.4 0.1 2.0 1 1 1 2 2 2 0 YhjQ protein MIF4G PF02854.14 ETO10569.1 - 5.5e-21 74.9 2.4 1.2e-19 70.5 1.6 2.1 1 1 0 1 1 1 1 MIF4G domain WD40 PF00400.27 ETO10570.1 - 7.3e-15 54.2 1.4 2.2e-09 36.8 0.2 3.3 3 1 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO10570.1 - 0.0018 16.5 0.2 0.72 7.9 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF1900 PF08954.6 ETO10570.1 - 0.07 12.6 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1900) WD40 PF00400.27 ETO10571.1 - 4.7e-27 92.8 4.1 7.5e-11 41.4 0.2 3.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO10571.1 - 0.00057 18.1 1.3 0.72 7.9 0.1 2.9 1 1 2 3 3 3 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO10571.1 - 0.016 14.9 1.2 5 6.9 0.0 3.1 1 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Kelch_6 PF13964.1 ETO10571.1 - 0.32 11.2 3.0 16 5.8 0.1 3.2 3 0 0 3 3 3 0 Kelch motif BAF1_ABF1 PF04684.8 ETO10572.1 - 0.0017 17.3 7.3 0.0017 17.3 5.0 1.1 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Mucin PF01456.12 ETO10572.1 - 0.021 14.6 12.9 0.03 14.1 8.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Ndc1_Nup PF09531.5 ETO10572.1 - 0.047 12.1 7.2 0.047 12.1 5.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Sec10 PF07393.6 ETO10572.1 - 0.49 8.5 8.2 0.53 8.3 5.7 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec10 Atrophin-1 PF03154.10 ETO10572.1 - 0.92 7.5 19.7 1.2 7.2 13.7 1.0 1 0 0 1 1 1 0 Atrophin-1 family DNA_pol_viral_N PF00242.12 ETO10572.1 - 3.5 6.5 15.0 4.1 6.3 10.4 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain MSP1_C PF07462.6 ETO10572.1 - 4.3 5.6 7.3 5.1 5.3 5.1 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF2572 PF10833.3 ETO10572.1 - 5.3 6.3 7.4 6.6 6.0 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) DUF966 PF06136.8 ETO10572.1 - 6.1 6.1 13.8 7.3 5.8 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SOG2 PF10428.4 ETO10572.1 - 6.5 5.2 21.9 8.2 4.9 15.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF3298 PF11738.3 ETO10573.1 - 0.12 12.8 0.4 0.35 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3298) Aa_trans PF01490.13 ETO10574.1 - 3.5e-18 65.2 8.5 4.2e-18 65.0 5.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1301 PF06979.7 ETO10574.1 - 0.019 15.1 0.4 0.041 14.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1301) XK-related PF09815.4 ETO10574.1 - 0.02 13.9 5.6 0.026 13.5 3.9 1.3 1 0 0 1 1 1 0 XK-related protein DUF3278 PF11683.3 ETO10574.1 - 0.047 13.6 4.9 0.36 10.8 0.4 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3278) RICTOR_V PF14668.1 ETO10574.1 - 0.11 12.4 2.4 6.2 6.8 0.1 2.5 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 UPF0118 PF01594.11 ETO10574.1 - 0.5 9.2 5.5 4.8 6.0 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF20 Cytochrome-c551 PF10643.4 ETO10575.1 - 0.58 9.4 5.2 0.82 8.9 3.6 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 DDHD PF02862.12 ETO10575.1 - 1 9.1 18.7 0.36 10.5 11.1 1.6 1 1 1 2 2 2 0 DDHD domain RNase_H PF00075.19 ETO10577.1 - 5e-07 30.1 0.0 5.9e-07 29.8 0.0 1.0 1 0 0 1 1 1 1 RNase H SAP PF02037.22 ETO10578.1 - 9.6e-09 34.5 0.0 9.6e-09 34.5 0.0 2.6 3 0 0 3 3 3 1 SAP domain SAP30_Sin3_bdg PF13867.1 ETO10578.1 - 0.043 13.6 2.7 0.053 13.4 0.0 2.4 2 0 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF1688 PF07958.6 ETO10579.1 - 4.6e-140 466.8 0.0 5.2e-140 466.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) DUF2419 PF10343.4 ETO10579.1 - 0.0035 16.6 0.0 0.012 14.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2419) Erythro_esteras PF05139.9 ETO10579.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Erythromycin esterase PROCT PF08084.6 ETO10579.1 - 0.14 11.9 0.1 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 PROCT (NUC072) domain Glyco_hydro_10 PF00331.15 ETO10580.1 - 0.073 12.0 0.1 0.087 11.8 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 zf-C3HC4_2 PF13923.1 ETO10581.1 - 0.089 12.8 3.6 1.2 9.2 2.4 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO10581.1 - 0.42 10.4 3.7 0.91 9.4 1.1 2.5 2 1 0 2 2 2 0 Ring finger domain Tetraspannin PF00335.15 ETO10582.1 - 0.13 11.4 1.3 0.22 10.7 0.4 1.8 2 0 0 2 2 2 0 Tetraspanin family Mem_trans PF03547.13 ETO10583.1 - 0.044 12.0 0.3 0.041 12.1 0.2 1.1 1 0 0 1 1 1 0 Membrane transport protein VHP PF02209.14 ETO10584.1 - 2.3e-15 55.9 7.1 3e-15 55.6 3.6 1.9 2 0 0 2 2 2 1 Villin headpiece domain SAM_2 PF07647.12 ETO10586.1 - 2.6e-08 33.5 0.1 5.3e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO10586.1 - 2.7e-05 24.2 0.2 6.3e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) KSR1-SAM PF13543.1 ETO10586.1 - 0.012 15.3 1.0 0.012 15.3 0.7 2.7 1 1 2 3 3 3 0 SAM like domain present in kinase suppressor RAS 1 AAA_32 PF13654.1 ETO10586.1 - 0.018 13.7 10.3 0.025 13.2 6.6 1.5 1 1 1 2 2 2 0 AAA domain GST_C PF00043.20 ETO10586.1 - 0.093 12.7 0.5 0.37 10.7 0.1 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF1664 PF07889.7 ETO10586.1 - 0.87 9.3 10.2 0.8 9.5 3.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Adenylsucc_synt PF00709.16 ETO10586.1 - 1.3 7.6 6.7 7 5.1 4.6 1.9 1 1 0 1 1 1 0 Adenylosuccinate synthetase Syntaxin-6_N PF09177.6 ETO10586.1 - 1.9 8.9 8.5 1.1 9.6 1.9 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Ferritin PF00210.19 ETO10586.1 - 2.1 8.0 8.8 5.1 6.8 6.1 2.0 1 1 0 1 1 1 0 Ferritin-like domain GrpE PF01025.14 ETO10586.1 - 2.2 7.7 11.1 1.9 7.9 5.2 2.2 1 1 1 2 2 2 0 GrpE DUF3347 PF11827.3 ETO10586.1 - 4.3 7.3 10.7 5.1 7.0 6.9 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) L31 PF09784.4 ETO10586.1 - 4.4 7.4 5.4 2.2 8.4 1.2 2.3 1 1 0 2 2 2 0 Mitochondrial ribosomal protein L31 BLOC1_2 PF10046.4 ETO10586.1 - 7.9 6.6 16.3 1 9.5 4.6 3.0 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 ETO10586.1 - 8.9 5.8 14.2 12 5.4 9.7 1.4 1 1 0 1 1 1 0 IncA protein DUF3908 PF13048.1 ETO10588.1 - 0.07 13.1 0.5 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3908) CYTL1 PF15153.1 ETO10591.1 - 0.029 14.0 0.7 0.036 13.7 0.5 1.1 1 0 0 1 1 1 0 Cytokine-like protein 1 IFP_35_N PF07334.8 ETO10591.1 - 0.61 10.0 6.2 0.21 11.5 2.1 1.8 1 1 1 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus BRICHOS PF04089.9 ETO10591.1 - 0.63 9.9 4.5 0.65 9.8 2.1 1.6 1 1 1 2 2 2 0 BRICHOS domain Acyltransferase PF01553.16 ETO10593.1 - 3.1e-12 46.0 0.0 3.9e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DUF1640 PF07798.6 ETO10594.1 - 0.016 15.3 1.4 0.021 14.8 0.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Bap31 PF05529.7 ETO10594.1 - 0.033 13.6 0.5 0.035 13.5 0.4 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like ACT_5 PF13710.1 ETO10594.1 - 0.18 11.6 0.6 0.26 11.1 0.4 1.2 1 0 0 1 1 1 0 ACT domain Mto2_bdg PF12808.2 ETO10594.1 - 1.4 9.0 9.0 1.5 9.0 1.4 2.3 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Herpes_BLRF2 PF05812.7 ETO10594.1 - 1.7 8.5 7.2 3.6 7.4 5.0 1.6 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein Cep57_CLD_2 PF14197.1 ETO10594.1 - 4.4 7.3 8.9 5.9 6.9 1.8 2.2 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 HSP90 PF00183.13 ETO10595.1 - 1.5e-45 155.6 18.8 3.7e-37 127.9 1.7 2.2 2 0 0 2 2 2 2 Hsp90 protein DUF4366 PF14283.1 ETO10595.1 - 0.01 15.2 0.4 0.014 14.8 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) GnHR_trans PF12369.3 ETO10595.1 - 0.029 14.8 4.2 0.036 14.5 1.2 2.3 2 0 0 2 2 2 0 Gonadotropin hormone receptor transmembrane region ATG11 PF10377.4 ETO10595.1 - 0.037 13.9 3.6 2 8.3 1.0 2.5 2 0 0 2 2 2 0 Autophagy-related protein 11 TPR_12 PF13424.1 ETO10596.1 - 2.2e-52 174.8 11.9 2.7e-19 68.8 0.3 4.4 1 1 1 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO10596.1 - 1.5e-33 114.2 18.5 7.1e-14 51.2 1.0 3.8 4 0 0 4 4 4 3 TPR repeat TPR_2 PF07719.12 ETO10596.1 - 1.6e-28 96.3 24.4 2.5e-05 23.8 0.3 7.3 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.1 ETO10596.1 - 2.1e-28 95.8 5.6 1.7e-05 24.2 0.0 6.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.23 ETO10596.1 - 6e-26 88.9 36.0 2.2e-06 27.0 0.2 6.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETO10596.1 - 1.7e-23 81.7 0.0 3.5e-05 23.5 0.0 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO10596.1 - 4e-18 63.7 37.2 0.0026 17.4 0.4 7.8 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_6 PF13174.1 ETO10596.1 - 2.4e-08 33.8 4.1 0.21 12.1 0.2 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO10596.1 - 7e-07 28.3 0.7 0.091 12.0 0.1 4.4 4 0 0 4 4 4 2 SHNi-TPR MIT PF04212.13 ETO10596.1 - 3.3e-06 26.8 11.5 0.55 10.1 0.1 5.9 5 0 0 5 5 5 2 MIT (microtubule interacting and transport) domain TPR_17 PF13431.1 ETO10596.1 - 7.9e-06 25.6 10.3 14 6.1 0.0 7.2 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETO10596.1 - 8.5e-05 22.8 0.0 2.6 8.9 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO10596.1 - 0.00019 21.4 1.0 0.00019 21.4 0.7 3.9 3 2 1 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 ETO10596.1 - 0.0007 20.2 0.0 1.5 9.6 0.0 3.3 1 1 2 3 3 3 1 Tetratricopeptide repeat ATP-synt_E PF05680.7 ETO10598.1 - 0.67 9.9 6.0 3.7 7.5 0.1 2.4 2 0 0 2 2 2 0 ATP synthase E chain Pap_E4 PF02711.9 ETO10598.1 - 3 8.7 4.9 17 6.3 0.0 2.8 1 1 2 3 3 3 0 E4 protein SNARE PF05739.14 ETO10599.1 - 1.1e-10 41.0 6.9 1.5e-10 40.5 4.8 1.2 1 0 0 1 1 1 1 SNARE domain Sipho_Gp157 PF05565.6 ETO10599.1 - 0.018 14.6 2.9 0.019 14.5 2.0 1.1 1 0 0 1 1 1 0 Siphovirus Gp157 DUF3450 PF11932.3 ETO10599.1 - 0.021 14.1 2.8 0.023 13.9 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Ran-binding PF05508.6 ETO10599.1 - 0.022 13.6 0.5 0.026 13.4 0.4 1.0 1 0 0 1 1 1 0 RanGTP-binding protein LPP20 PF02169.11 ETO10599.1 - 0.025 14.6 0.6 0.036 14.1 0.4 1.3 1 0 0 1 1 1 0 LPP20 lipoprotein DUF674 PF05056.7 ETO10599.1 - 0.04 12.5 0.5 0.044 12.4 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF674) Histidinol_dh PF00815.15 ETO10599.1 - 0.053 12.1 0.1 0.059 12.0 0.1 1.1 1 0 0 1 1 1 0 Histidinol dehydrogenase DUF745 PF05335.8 ETO10599.1 - 0.069 12.6 2.2 0.08 12.4 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) NAGidase PF07555.8 ETO10599.1 - 0.21 10.4 1.7 0.24 10.2 1.2 1.2 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase DUF1664 PF07889.7 ETO10599.1 - 1.5 8.5 5.4 1.9 8.2 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) UPF0184 PF03670.8 ETO10599.1 - 2.4 8.4 5.8 3.3 7.9 2.8 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) DUF2324 PF10086.4 ETO10600.1 - 0.0031 16.7 1.2 0.0047 16.1 0.8 1.5 1 0 0 1 1 1 1 Putative membrane peptidase family (DUF2324) AzlD PF05437.7 ETO10600.1 - 0.081 12.8 3.2 0.16 11.9 2.1 1.7 1 1 0 1 1 1 0 Branched-chain amino acid transport protein (AzlD) WD40 PF00400.27 ETO10601.1 - 4.7e-53 175.2 16.4 1.6e-10 40.4 0.2 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO10601.1 - 1.9e-08 32.9 7.2 0.022 12.8 0.0 4.9 1 1 4 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO10601.1 - 0.0036 16.1 9.2 0.4 9.3 0.2 4.5 1 1 2 3 3 3 3 Nup133 N terminal like Methyltransf_25 PF13649.1 ETO10601.1 - 0.019 15.2 0.0 0.6 10.4 0.0 3.0 3 2 0 3 3 3 0 Methyltransferase domain USP7_C2 PF14533.1 ETO10601.1 - 0.075 12.4 0.7 54 3.1 0.0 3.5 2 2 2 4 4 4 0 Ubiquitin-specific protease C-terminal Kelch_6 PF13964.1 ETO10602.1 - 0.0015 18.6 0.2 0.018 15.1 0.0 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.20 ETO10602.1 - 0.0065 15.9 0.1 0.46 10.0 0.0 2.8 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.1 ETO10602.1 - 0.071 13.0 0.1 9.7 6.2 0.0 2.8 2 0 0 2 2 2 0 Kelch motif Kelch_2 PF07646.10 ETO10602.1 - 0.16 11.8 0.4 5.4 6.9 0.0 3.1 3 1 0 3 3 3 0 Kelch motif PBP1_TM PF14812.1 ETO10604.1 - 0.093 13.0 0.6 0.093 13.0 0.4 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1493 PF07377.7 ETO10606.1 - 0.058 13.4 3.4 2.2 8.4 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF1493) TMF_TATA_bd PF12325.3 ETO10606.1 - 0.35 10.6 6.6 0.21 11.3 1.6 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding RST PF12174.3 ETO10607.1 - 0.15 11.8 1.1 9.2 6.1 0.2 2.6 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain WD40 PF00400.27 ETO10608.1 - 2.3e-30 103.3 3.7 4.6e-09 35.8 0.1 3.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Kelch_5 PF13854.1 ETO10609.1 - 0.0064 16.4 0.1 0.016 15.1 0.1 1.7 1 0 0 1 1 1 1 Kelch motif TMEM154 PF15102.1 ETO10610.1 - 0.019 14.6 0.4 0.072 12.7 0.3 1.9 1 0 0 1 1 1 0 TMEM154 protein family Ribosomal_60s PF00428.14 ETO10611.1 - 0.073 13.4 13.9 3.1 8.2 9.6 2.2 1 1 0 1 1 1 0 60s Acidic ribosomal protein gpUL132 PF11359.3 ETO10611.1 - 0.25 10.6 3.5 0.26 10.5 2.4 1.1 1 0 0 1 1 1 0 Glycoprotein UL132 NOA36 PF06524.7 ETO10611.1 - 0.33 10.1 11.3 0.36 10.0 7.9 1.0 1 0 0 1 1 1 0 NOA36 protein Zip PF02535.17 ETO10611.1 - 1.9 7.3 6.4 2.1 7.2 4.4 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Nucleo_P87 PF07267.6 ETO10611.1 - 2.6 6.6 8.5 3 6.4 5.9 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TFIIF_alpha PF05793.7 ETO10611.1 - 2.6 6.2 18.1 2.9 6.1 12.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DDHD PF02862.12 ETO10611.1 - 4.5 6.9 8.6 4.6 6.9 6.0 1.2 1 0 0 1 1 1 0 DDHD domain Apt1 PF10351.4 ETO10611.1 - 6.3 5.5 12.4 6.4 5.5 8.6 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1510 PF07423.6 ETO10611.1 - 7.7 5.8 17.8 8.6 5.6 12.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) ASFV_J13L PF05568.6 ETO10612.1 - 0.013 15.0 1.8 0.015 14.8 1.2 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein ODV-E18 PF10717.4 ETO10612.1 - 0.014 14.8 0.5 0.022 14.2 0.3 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Plant_vir_prot PF01307.12 ETO10612.1 - 0.056 13.1 0.2 0.068 12.8 0.1 1.3 1 0 0 1 1 1 0 Plant viral movement protein TMEM154 PF15102.1 ETO10612.1 - 0.064 12.9 1.1 0.064 12.9 0.8 1.5 2 0 0 2 2 2 0 TMEM154 protein family NVEALA PF14055.1 ETO10612.1 - 0.14 11.8 3.7 0.27 10.9 2.1 1.8 1 1 1 2 2 2 0 NVEALA protein Baculo_11_kDa PF06143.6 ETO10612.1 - 0.17 11.2 2.7 0.29 10.5 1.9 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family Rifin_STEVOR PF02009.11 ETO10612.1 - 0.36 10.4 3.8 0.58 9.7 2.6 1.3 1 0 0 1 1 1 0 Rifin/stevor family OppC_N PF12911.2 ETO10612.1 - 0.38 10.1 2.2 0.5 9.7 0.7 1.8 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF3753 PF12575.3 ETO10612.1 - 0.98 9.2 8.9 0.99 9.2 5.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3753) Bap31 PF05529.7 ETO10612.1 - 5.9 6.3 8.2 1.8 8.0 0.8 2.1 1 1 0 2 2 2 0 B-cell receptor-associated protein 31-like GvpL_GvpF PF06386.6 ETO10613.1 - 3.4 7.1 10.3 0.085 12.4 2.8 1.6 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Gpi16 PF04113.9 ETO10614.1 - 1.1e-29 102.8 0.0 1.3e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Lipase3_N PF03893.11 ETO10614.1 - 0.0047 16.6 0.1 0.94 9.3 0.0 2.5 3 0 0 3 3 3 2 Lipase 3 N-terminal region TPR_12 PF13424.1 ETO10615.1 - 4.7e-85 279.5 41.3 9.3e-20 70.3 2.9 6.8 5 2 2 7 7 7 7 Tetratricopeptide repeat TPR_11 PF13414.1 ETO10615.1 - 5.7e-47 157.2 35.8 6.7e-12 44.8 3.9 6.3 5 1 1 6 6 6 5 TPR repeat TPR_1 PF00515.23 ETO10615.1 - 7.6e-40 132.9 60.2 3.5e-07 29.5 1.6 10.2 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_7 PF13176.1 ETO10615.1 - 4.3e-39 129.2 21.8 4.2e-06 26.1 0.0 10.7 9 1 1 10 10 10 8 Tetratricopeptide repeat TPR_10 PF13374.1 ETO10615.1 - 3.1e-37 125.4 0.0 1.8e-05 24.4 0.0 8.6 8 1 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.12 ETO10615.1 - 2.9e-35 117.3 47.4 1.2e-06 27.9 0.7 10.5 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_8 PF13181.1 ETO10615.1 - 1e-22 78.1 79.1 3.6e-06 26.3 2.7 10.4 10 1 1 11 11 11 7 Tetratricopeptide repeat TPR_17 PF13431.1 ETO10615.1 - 2.2e-20 71.1 18.8 0.017 15.3 0.0 9.5 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 ETO10615.1 - 7.1e-17 61.5 0.6 1.6e-05 25.3 0.2 5.7 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.1 ETO10615.1 - 2.4e-09 37.0 16.1 0.12 12.9 0.1 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO10615.1 - 6.7e-09 35.6 0.0 3.6 8.4 0.0 7.1 6 1 1 7 7 7 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO10615.1 - 4.2e-08 33.2 29.3 0.012 15.7 0.5 5.7 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO10615.1 - 2e-06 28.0 7.4 0.59 10.5 0.0 5.5 3 1 2 5 5 5 2 Tetratricopeptide repeat Ten1_2 PF15490.1 ETO10615.1 - 0.0013 18.2 0.1 7.4 6.1 0.0 4.9 3 2 1 4 4 4 1 Telomere-capping, CST complex subunit PPR PF01535.15 ETO10615.1 - 0.0016 18.2 21.9 0.1 12.5 0.2 7.3 7 0 0 7 7 7 1 PPR repeat TPR_3 PF07720.7 ETO10615.1 - 0.2 11.4 27.6 0.14 11.9 1.5 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat WD40 PF00400.27 ETO10616.1 - 3.2e-10 39.4 1.3 5e-10 38.8 0.9 1.3 1 0 0 1 1 1 1 WD domain, G-beta repeat DUF342 PF03961.8 ETO10616.1 - 0.011 14.2 2.3 0.0098 14.3 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Orbi_VP5 PF00901.12 ETO10616.1 - 0.011 13.9 1.5 0.011 13.9 1.0 1.0 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 She9_MDM33 PF05546.6 ETO10616.1 - 0.019 14.5 4.5 0.025 14.1 3.1 1.2 1 0 0 1 1 1 0 She9 / Mdm33 family Geminin PF07412.7 ETO10616.1 - 0.032 13.9 4.9 0.032 13.9 3.4 1.5 1 1 0 1 1 1 0 Geminin GLTP PF08718.6 ETO10616.1 - 0.041 13.9 1.0 0.052 13.5 0.7 1.1 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) PhoU PF01895.14 ETO10616.1 - 0.22 12.0 1.4 0.29 11.6 0.9 1.2 1 0 0 1 1 1 0 PhoU domain Med4 PF10018.4 ETO10616.1 - 0.6 9.4 3.9 0.66 9.3 2.7 1.1 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Atg14 PF10186.4 ETO10616.1 - 0.84 8.5 4.7 1 8.2 3.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 GLE1 PF07817.8 ETO10616.1 - 0.88 8.4 6.4 0.97 8.3 4.4 1.0 1 0 0 1 1 1 0 GLE1-like protein Vfa1 PF08432.5 ETO10616.1 - 1.5 8.8 7.4 3.8 7.5 5.1 1.7 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DivIC PF04977.10 ETO10616.1 - 8.4 5.9 10.8 9.9 5.7 6.0 1.9 1 1 1 2 2 2 0 Septum formation initiator ABC_membrane_2 PF06472.10 ETO10617.1 - 5.9e-14 51.8 5.7 5.9e-07 28.8 0.1 2.0 2 0 0 2 2 2 2 ABC transporter transmembrane region 2 DSPc PF00782.15 ETO10619.1 - 1.1e-25 89.6 0.1 1.3e-25 89.5 0.1 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain NT-C2 PF10358.4 ETO10619.1 - 0.03 13.8 0.6 0.049 13.1 0.4 1.4 1 1 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins CDKN3 PF05706.7 ETO10619.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.4 1 1 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) MSA-2c PF12238.3 ETO10619.1 - 0.12 12.0 0.5 0.13 11.8 0.4 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c WD40 PF00400.27 ETO10620.1 - 1.8e-27 94.1 1.7 1.9e-10 40.2 0.0 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO10620.1 - 0.0015 16.7 1.1 4.5 5.2 0.0 2.9 1 1 2 3 3 3 3 Nucleoporin Nup120/160 zf-RVT PF13966.1 ETO10621.1 - 1.1e-06 28.8 0.4 3.1e-06 27.3 0.2 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.22 ETO10621.1 - 0.00038 19.8 0.2 0.00067 19.0 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HU-DNA_bdg PF14848.1 ETO10623.1 - 0.0061 16.2 0.4 0.0093 15.6 0.3 1.2 1 0 0 1 1 1 1 DNA-binding domain Methyltransf_10 PF05971.7 ETO10623.1 - 0.12 11.4 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF890) WD40 PF00400.27 ETO10624.1 - 5.1e-26 89.5 0.7 1.2e-08 34.4 0.0 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO10624.1 - 0.057 12.1 1.3 2.8 6.5 0.0 2.3 1 1 1 2 2 2 0 Nup133 N terminal like Nup160 PF11715.3 ETO10624.1 - 0.14 10.2 0.0 1.3 7.0 0.0 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Microvir_J PF04726.8 ETO10624.1 - 0.65 10.0 0.0 0.65 10.0 0.0 2.3 2 0 0 2 2 2 0 Microvirus J protein Exo_endo_phos_2 PF14529.1 ETO10625.1 - 0.0033 17.0 0.1 0.0046 16.5 0.1 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Nfu_N PF08712.6 ETO10627.1 - 7e-20 70.4 0.3 1.5e-19 69.4 0.2 1.5 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 ETO10627.1 - 9.3e-19 66.9 0.0 1.6e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain PAP_central PF04928.12 ETO10629.1 - 0.056 12.2 0.2 0.13 11.0 0.1 1.5 1 0 0 1 1 1 0 Poly(A) polymerase central domain DUF1049 PF06305.6 ETO10629.1 - 0.075 12.5 1.8 1.6 8.2 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) PH PF00169.24 ETO10630.1 - 1.2e-07 31.9 1.1 1.2e-07 31.9 0.8 2.3 2 1 0 2 2 2 1 PH domain Mucin PF01456.12 ETO10630.1 - 9.9e-06 25.3 15.0 9.9e-06 25.3 10.4 2.6 3 0 0 3 3 3 1 Mucin-like glycoprotein PH_8 PF15409.1 ETO10630.1 - 0.0025 17.8 0.2 0.0091 16.0 0.1 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 ETO10630.1 - 0.033 14.4 0.2 0.033 14.4 0.1 2.8 3 1 0 3 3 3 0 Pleckstrin homology domain AAT PF03417.11 ETO10631.1 - 0.071 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase DUF805 PF05656.9 ETO10632.1 - 8.5e-05 22.3 3.8 0.00012 21.8 2.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF805) 7TMR-DISM_7TM PF07695.6 ETO10632.1 - 0.00016 21.4 6.3 0.00023 20.9 4.3 1.2 1 0 0 1 1 1 1 7TM diverse intracellular signalling NAAA-beta PF15508.1 ETO10632.1 - 0.00027 21.2 0.0 0.0004 20.6 0.0 1.3 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF4271 PF14093.1 ETO10632.1 - 0.0025 17.5 17.0 0.13 11.8 7.3 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4271) 7TM-7TMR_HD PF07698.6 ETO10632.1 - 0.0045 16.4 13.1 0.049 13.0 8.1 2.0 1 1 1 2 2 2 1 7TM receptor with intracellular HD hydrolase EcsB PF05975.7 ETO10632.1 - 0.0045 15.5 4.7 0.0062 15.0 3.2 1.2 1 0 0 1 1 1 1 Bacterial ABC transporter protein EcsB ODV-E18 PF10717.4 ETO10632.1 - 0.013 14.9 0.6 0.013 14.9 0.4 3.1 2 1 1 3 3 2 0 Occlusion-derived virus envelope protein ODV-E18 Oxidored_q3 PF00499.15 ETO10632.1 - 0.032 14.0 9.5 0.039 13.7 2.3 2.1 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF3357 PF11837.3 ETO10632.1 - 0.033 14.0 0.1 6.1 6.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Ninjurin PF04923.7 ETO10632.1 - 0.035 13.8 3.7 0.29 10.8 0.9 2.1 2 0 0 2 2 2 0 Ninjurin EamA PF00892.15 ETO10632.1 - 0.036 14.1 4.1 1.8 8.6 0.7 2.3 2 0 0 2 2 2 0 EamA-like transporter family ABC2_membrane_5 PF13346.1 ETO10632.1 - 0.055 12.7 15.3 0.28 10.4 6.6 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF2566 PF10753.4 ETO10632.1 - 0.06 13.2 0.5 0.06 13.2 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2566) PGG PF13962.1 ETO10632.1 - 0.073 12.6 1.1 0.21 11.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function EpsG PF14897.1 ETO10632.1 - 0.085 11.7 19.1 0.037 12.9 6.1 2.0 1 1 0 2 2 2 0 EpsG family Tetraspannin PF00335.15 ETO10632.1 - 0.098 11.9 11.1 0.2 10.9 4.2 2.1 2 0 0 2 2 2 0 Tetraspanin family DUF4231 PF14015.1 ETO10632.1 - 0.11 12.4 1.9 0.14 12.1 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) Cytochrom_B_C PF00032.12 ETO10632.1 - 0.15 12.2 4.9 0.3 11.3 0.7 2.2 2 0 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD DUF4199 PF13858.1 ETO10632.1 - 0.18 11.7 8.4 0.84 9.5 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) O-antigen_lig PF13425.1 ETO10632.1 - 0.19 11.7 10.4 0.38 10.7 1.5 2.1 2 0 0 2 2 2 0 O-antigen ligase like membrane protein DUF1049 PF06305.6 ETO10632.1 - 0.19 11.2 1.3 5.6 6.5 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF4401 PF14351.1 ETO10632.1 - 0.2 10.6 5.7 0.042 12.8 0.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4401) SUR7 PF06687.7 ETO10632.1 - 0.24 10.9 5.8 1.1 8.7 1.6 2.0 2 0 0 2 2 2 0 SUR7/PalI family DUF4153 PF13687.1 ETO10632.1 - 0.29 10.6 12.6 0.39 10.2 3.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4153) OST3_OST6 PF04756.8 ETO10632.1 - 0.38 10.3 9.7 1.5 8.3 2.4 2.1 2 0 0 2 2 2 0 OST3 / OST6 family Gemini_mov PF01708.11 ETO10632.1 - 0.4 10.2 3.7 0.7 9.4 0.2 2.5 2 1 1 3 3 3 0 Geminivirus putative movement protein DUF4064 PF13273.1 ETO10632.1 - 0.43 10.7 13.9 0.53 10.4 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF3021 PF11457.3 ETO10632.1 - 0.57 10.0 11.8 4.6 7.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) EXS PF03124.9 ETO10632.1 - 0.71 8.8 7.4 1.8 7.5 5.2 1.7 1 1 0 1 1 1 0 EXS family MscS_TM PF12794.2 ETO10632.1 - 0.81 8.2 5.6 0.34 9.4 0.5 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 FtsH_ext PF06480.10 ETO10632.1 - 1.1 9.4 9.8 5.1 7.3 0.3 3.1 3 0 0 3 3 3 0 FtsH Extracellular DUF4131 PF13567.1 ETO10632.1 - 1.3 8.4 6.0 19 4.6 0.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) FtsX PF02687.16 ETO10632.1 - 1.3 8.8 13.2 3.7 7.3 0.3 2.4 2 1 0 2 2 2 0 FtsX-like permease family PIG-F PF06699.6 ETO10632.1 - 1.6 8.5 8.6 3.2 7.6 0.7 2.7 1 1 2 3 3 3 0 GPI biosynthesis protein family Pig-F PKD_channel PF08016.7 ETO10632.1 - 2.6 6.3 8.8 3.3 6.0 6.1 1.1 1 0 0 1 1 1 0 Polycystin cation channel ABC2_membrane_4 PF12730.2 ETO10632.1 - 2.7 7.0 21.0 2e+02 0.9 14.6 2.1 1 1 0 1 1 1 0 ABC-2 family transporter protein RDD PF06271.7 ETO10632.1 - 2.8 7.8 17.2 80 3.1 10.2 2.3 2 1 0 2 2 1 0 RDD family EphA2_TM PF14575.1 ETO10632.1 - 5.1 7.5 11.0 6 7.3 0.0 3.0 2 1 1 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Glucos_trans_II PF14264.1 ETO10632.1 - 5.4 5.9 16.9 7.1e+02 -1.1 11.9 2.1 1 1 0 1 1 1 0 Glucosyl transferase GtrII DUF3810 PF12725.2 ETO10632.1 - 6.3 5.6 8.2 2.1 7.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) TrbL PF04610.9 ETO10632.1 - 6.5 6.3 11.7 0.31 10.6 1.7 2.0 2 0 0 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein DUF4389 PF14333.1 ETO10632.1 - 7.9 6.2 9.3 7.7 6.3 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4389) DUF4149 PF13664.1 ETO10632.1 - 9.2 6.3 8.4 21 5.2 2.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) DUF3278 PF11683.3 ETO10632.1 - 9.9 6.1 10.8 20 5.1 4.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) Bowman-Birk_leg PF00228.15 ETO10633.1 - 0.14 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Bowman-Birk serine protease inhibitor family EF-hand_1 PF00036.27 ETO10634.1 - 2.2e-13 48.4 0.6 2.7e-05 23.1 0.0 3.1 2 0 0 2 2 2 2 EF hand SpoU_methylase PF00588.14 ETO10634.1 - 2.1e-12 47.1 0.0 1.6e-11 44.2 0.0 2.1 2 0 0 2 2 2 1 SpoU rRNA Methylase family EF-hand_6 PF13405.1 ETO10634.1 - 1.5e-10 40.0 2.0 2.9e-05 23.5 0.1 3.5 2 1 1 3 3 3 2 EF-hand domain EF-hand_4 PF12763.2 ETO10634.1 - 9.2e-10 38.1 2.9 4.8e-05 23.0 0.4 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 ETO10634.1 - 1.3e-09 37.9 10.7 5.9e-07 29.5 0.4 2.6 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 ETO10634.1 - 1.4e-09 36.8 5.4 3.9e-05 22.8 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 ETO10634.1 - 2.3e-07 30.3 2.0 0.005 16.4 0.1 2.6 1 1 1 2 2 2 2 EF-hand domain pair zf-TRAF PF02176.13 ETO10635.1 - 6.1e-06 26.5 4.8 6.1e-06 26.5 3.3 1.9 2 0 0 2 2 2 1 TRAF-type zinc finger WD40 PF00400.27 ETO10635.1 - 0.0069 16.2 0.2 0.016 15.0 0.1 1.7 1 0 0 1 1 1 1 WD domain, G-beta repeat zf-C2H2_jaz PF12171.3 ETO10636.1 - 5.7e-09 35.8 10.1 3.8e-05 23.7 1.3 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 ETO10636.1 - 4.9e-07 29.7 10.0 0.0031 17.6 1.4 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 ETO10636.1 - 8.6e-07 28.9 20.0 1.9e-05 24.7 2.3 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 ETO10636.1 - 8.3e-06 25.5 6.7 0.012 15.4 0.5 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 ETO10636.1 - 2.1e-05 24.5 14.8 0.0033 17.6 0.8 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETO10636.1 - 3.9e-05 23.7 17.9 0.00058 20.0 0.3 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-BED PF02892.10 ETO10636.1 - 0.0015 18.2 9.7 0.064 13.0 0.9 3.3 2 1 1 3 3 3 2 BED zinc finger zf-DNA_Pol PF08996.5 ETO10636.1 - 0.015 14.6 1.7 0.015 14.6 1.2 1.9 2 1 0 2 2 2 0 DNA Polymerase alpha zinc finger RGCC PF15151.1 ETO10636.1 - 0.025 15.0 0.0 0.066 13.6 0.0 1.7 2 0 0 2 2 1 0 Response gene to complement 32 protein family DUF4428 PF14471.1 ETO10636.1 - 0.12 12.1 0.9 0.37 10.5 0.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4428) SprT-like PF10263.4 ETO10636.1 - 0.42 10.2 8.6 0.061 12.9 1.8 2.5 1 1 0 2 2 2 0 SprT-like family C1_4 PF07975.7 ETO10636.1 - 0.44 10.5 4.6 6.6 6.8 3.2 2.4 1 1 1 2 2 2 0 TFIIH C1-like domain zf-C3HC4_3 PF13920.1 ETO10636.1 - 0.62 9.7 3.2 2 8.1 1.9 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Endonuclease_7 PF02945.10 ETO10636.1 - 0.73 9.5 4.3 1.3 8.7 2.4 1.8 1 1 0 1 1 1 0 Recombination endonuclease VII Sgf11 PF08209.6 ETO10636.1 - 0.79 9.0 3.0 17 4.8 0.2 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-Di19 PF05605.7 ETO10636.1 - 1.1 9.4 10.3 0.13 12.4 3.9 1.9 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 ETO10636.1 - 3.9 7.2 4.9 10 5.9 0.1 3.1 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Evr1_Alr PF04777.8 ETO10636.1 - 9.4 6.2 13.6 21 5.0 1.4 3.1 2 2 1 3 3 3 0 Erv1 / Alr family DDE_3 PF13358.1 ETO10637.1 - 1.7e-17 63.5 2.5 3.1e-17 62.6 1.0 1.6 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 ETO10637.1 - 5.6e-07 29.5 0.8 1.4e-06 28.2 0.6 1.7 1 0 0 1 1 1 1 Transposase rve PF00665.21 ETO10637.1 - 0.00016 21.7 0.0 0.00049 20.2 0.0 1.9 1 1 0 1 1 1 1 Integrase core domain zf-CCHC_4 PF14392.1 ETO10638.1 - 0.0066 16.0 3.9 0.34 10.6 0.4 2.7 1 1 1 2 2 2 2 Zinc knuckle HMG_box_5 PF14887.1 ETO10638.1 - 0.071 12.9 0.2 0.17 11.6 0.1 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box 5 zf-CCHC PF00098.18 ETO10638.1 - 0.077 12.9 0.3 0.077 12.9 0.2 2.5 2 0 0 2 2 2 0 Zinc knuckle Tup_N PF08581.5 ETO10640.1 - 0.043 14.0 0.3 0.16 12.2 0.2 1.9 1 0 0 1 1 1 0 Tup N-terminal DAG_kinase_N PF14513.1 ETO10640.1 - 0.3 11.2 5.2 0.47 10.6 3.2 1.8 1 1 0 1 1 1 0 Diacylglycerol kinase N-terminus SID-1_RNA_chan PF13965.1 ETO10640.1 - 0.69 8.0 5.4 0.82 7.7 3.7 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Mucin PF01456.12 ETO10640.1 - 1.6 8.5 19.6 2.7 7.7 13.6 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein MGC-24 PF05283.6 ETO10640.1 - 1.8 8.2 14.2 3.1 7.5 9.8 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) YfhO PF09586.5 ETO10640.1 - 6.1 4.7 11.9 6.6 4.6 8.3 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO BAF1_ABF1 PF04684.8 ETO10641.1 - 0.13 11.1 4.2 0.14 10.9 2.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RBFA PF02033.13 ETO10642.1 - 0.0012 18.7 0.0 0.0038 17.2 0.0 1.9 1 1 0 1 1 1 1 Ribosome-binding factor A CsgE PF10627.4 ETO10643.1 - 0.12 12.2 0.1 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Curli assembly protein CsgE Spc7 PF08317.6 ETO10645.1 - 0.01 14.5 8.0 0.012 14.2 5.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein LPP PF04728.8 ETO10645.1 - 0.023 14.4 0.1 0.074 12.8 0.0 1.8 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Shugoshin_N PF07558.6 ETO10645.1 - 0.033 13.9 1.7 0.09 12.5 0.6 2.1 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region HALZ PF02183.13 ETO10645.1 - 0.035 13.8 0.4 0.035 13.8 0.3 2.7 2 1 1 3 3 3 0 Homeobox associated leucine zipper DUF3573 PF12097.3 ETO10645.1 - 0.04 12.5 4.2 0.047 12.3 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) ACCA PF03255.9 ETO10645.1 - 0.042 13.3 0.7 0.073 12.6 0.5 1.4 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit ERM PF00769.14 ETO10645.1 - 0.069 12.6 14.8 0.082 12.4 10.2 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family WD40_alt PF14077.1 ETO10645.1 - 0.086 12.4 0.3 0.16 11.6 0.2 1.4 1 0 0 1 1 1 0 Alternative WD40 repeat motif MRP-S26 PF14943.1 ETO10645.1 - 0.14 11.7 12.0 0.17 11.3 8.3 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Dna2 PF08696.6 ETO10645.1 - 0.17 11.1 5.9 0.088 12.1 2.7 1.6 2 0 0 2 2 2 0 DNA replication factor Dna2 ApoO PF09769.4 ETO10645.1 - 0.2 11.3 1.6 0.31 10.7 1.1 1.3 1 0 0 1 1 1 0 Apolipoprotein O ADIP PF11559.3 ETO10645.1 - 0.28 11.0 16.7 0.42 10.4 11.6 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding CP12 PF02672.10 ETO10645.1 - 0.48 10.9 5.2 0.3 11.5 2.1 1.9 1 1 0 1 1 1 0 CP12 domain GNT-I PF03071.10 ETO10645.1 - 0.49 8.8 2.6 0.63 8.5 1.8 1.1 1 0 0 1 1 1 0 GNT-I family DUF3752 PF12572.3 ETO10645.1 - 0.62 10.1 8.2 0.77 9.8 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) ZYG-11_interact PF05884.7 ETO10645.1 - 1.4 7.9 3.7 1.2 8.1 2.0 1.3 1 1 0 1 1 1 0 Interactor of ZYG-11 APG6 PF04111.7 ETO10645.1 - 1.4 7.8 13.2 1.7 7.6 9.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Paramyxo_ncap PF00973.14 ETO10645.1 - 1.5 7.4 7.6 1.7 7.2 5.3 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF4407 PF14362.1 ETO10645.1 - 3.6 6.4 6.2 4.4 6.1 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MAD PF05557.8 ETO10645.1 - 4.5 5.2 17.4 6.3 4.7 12.1 1.3 1 1 0 1 1 1 0 Mitotic checkpoint protein Mnd1 PF03962.10 ETO10645.1 - 6 6.4 15.1 7.7 6.1 10.5 1.2 1 0 0 1 1 1 0 Mnd1 family L_lactis_ph-MCP PF06673.6 ETO10645.1 - 6.3 5.4 7.2 3.2 6.4 3.5 1.5 1 1 1 2 2 2 0 Lactococcus lactis bacteriophage major capsid protein OmpH PF03938.9 ETO10646.1 - 0.0078 16.1 4.2 0.011 15.7 2.9 1.3 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) PilJ PF13675.1 ETO10646.1 - 0.023 15.0 0.3 0.032 14.5 0.2 1.1 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term HNOB PF07700.10 ETO10646.1 - 0.039 13.4 0.2 0.052 13.0 0.2 1.3 1 0 0 1 1 1 0 Heme NO binding Tropomyosin_1 PF12718.2 ETO10646.1 - 0.051 13.4 4.5 0.048 13.5 2.6 1.3 1 1 0 1 1 1 0 Tropomyosin like NPV_P10 PF05531.7 ETO10646.1 - 0.06 13.6 0.4 0.27 11.5 0.0 1.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein ATG16 PF08614.6 ETO10646.1 - 0.11 12.3 4.2 3.3 7.4 0.1 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF3106 PF11304.3 ETO10646.1 - 0.14 12.5 6.8 0.21 12.0 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) 60KD_IMP PF02096.15 ETO10646.1 - 0.17 11.5 0.1 0.17 11.5 0.1 2.3 1 1 1 2 2 2 0 60Kd inner membrane protein DUF2800 PF10926.3 ETO10646.1 - 0.17 10.9 1.3 0.2 10.7 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2800) Pex24p PF06398.6 ETO10646.1 - 0.17 10.6 1.3 0.22 10.2 0.9 1.3 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin HJURP_C PF12347.3 ETO10646.1 - 0.18 11.3 5.6 0.51 9.9 1.2 2.3 1 1 1 2 2 2 0 Holliday junction regulator protein family C-terminal repeat Vps5 PF09325.5 ETO10646.1 - 0.21 10.8 6.5 0.071 12.3 2.3 1.6 1 1 1 2 2 2 0 Vps5 C terminal like Jnk-SapK_ap_N PF09744.4 ETO10646.1 - 0.32 10.9 10.5 0.41 10.6 7.2 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 HalX PF08663.5 ETO10646.1 - 0.39 10.7 4.1 12 6.0 0.4 2.4 2 1 0 2 2 2 0 HalX domain Surfac_D-trimer PF09006.6 ETO10646.1 - 1.4 8.6 6.2 0.45 10.2 0.2 2.2 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation DUF342 PF03961.8 ETO10646.1 - 1.9 6.8 6.9 2.2 6.6 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2457 PF10446.4 ETO10649.1 - 2.9 6.4 10.8 3.6 6.1 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PspB PF06667.7 ETO10650.1 - 0.0091 15.9 0.6 0.027 14.3 0.4 1.8 1 0 0 1 1 1 1 Phage shock protein B Neur_chan_memb PF02932.11 ETO10650.1 - 1.4 8.7 13.0 4.1 7.2 2.0 2.2 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Folate_carrier PF01770.13 ETO10650.1 - 2.4 6.5 7.6 4.9 5.5 1.5 2.2 2 0 0 2 2 2 0 Reduced folate carrier POX PF07526.6 ETO10650.1 - 2.9 8.1 7.3 1.8 8.7 0.4 2.4 2 0 0 2 2 2 0 Associated with HOX DUF3439 PF11921.3 ETO10651.1 - 0.0058 16.3 9.1 0.0058 16.3 6.3 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3439) SSP160 PF06933.6 ETO10651.1 - 0.0068 14.4 3.8 0.0075 14.3 2.6 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 Mucin PF01456.12 ETO10651.1 - 0.029 14.1 8.7 0.029 14.1 6.0 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein Herpes_UL49_5 PF05702.6 ETO10652.1 - 0.38 10.6 5.9 0.99 9.3 4.1 1.8 1 1 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein Renin_r PF07850.9 ETO10652.1 - 0.61 10.4 9.5 0.44 10.9 0.5 2.3 2 0 0 2 2 2 0 Renin receptor-like protein DUF939 PF06081.6 ETO10652.1 - 0.99 9.2 26.1 0.05 13.4 13.4 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF939) TcpE PF12648.2 ETO10652.1 - 5.3 7.2 15.1 1.1 9.3 3.7 2.3 2 0 0 2 2 2 0 TcpE family YqzM PF14141.1 ETO10652.1 - 6.2 6.6 9.6 17 5.3 6.6 1.7 1 0 0 1 1 1 0 YqzM-like protein WD40 PF00400.27 ETO10653.1 - 1.7e-60 198.8 20.6 3.8e-14 51.9 0.4 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 ETO10653.1 - 4.7e-07 29.7 0.0 0.0047 16.6 0.0 3.0 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO10653.1 - 2.7e-06 25.8 5.7 0.0043 15.2 3.9 3.4 1 1 0 1 1 1 1 Nucleoporin Nup120/160 PD40 PF07676.7 ETO10653.1 - 0.0001 21.8 3.1 5.6 6.7 0.0 4.5 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Gmad1 PF10647.4 ETO10653.1 - 0.00013 21.5 1.7 0.095 12.0 0.4 4.0 1 1 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain PQQ_2 PF13360.1 ETO10653.1 - 0.00028 20.4 2.4 0.0079 15.6 1.2 2.2 1 1 1 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 ETO10653.1 - 0.0014 17.4 11.1 0.016 13.9 7.8 2.3 1 1 0 1 1 1 1 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO10653.1 - 0.0024 16.2 2.0 0.25 9.5 0.1 2.7 1 1 2 3 3 3 3 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 ETO10653.1 - 0.03 13.6 12.6 12 5.2 0.1 5.4 4 1 1 5 5 5 0 Proteasome subunit A N-terminal signature TolB_N PF04052.8 ETO10653.1 - 0.046 13.7 0.1 38 4.4 0.0 3.8 5 0 0 5 5 4 0 TolB amino-terminal domain DUF3732 PF12532.3 ETO10653.1 - 0.057 12.9 0.2 31 4.0 0.0 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF3732) TFIIIC_sub6 PF10419.4 ETO10653.1 - 0.097 12.1 0.1 33 4.0 0.0 3.1 3 0 0 3 3 3 0 TFIIIC subunit Nbas_N PF15492.1 ETO10653.1 - 0.1 11.7 6.0 1.6 7.7 0.2 3.7 1 1 3 4 4 4 0 Neuroblastoma-amplified sequence, N terminal GET2 PF08690.5 ETO10654.1 - 3.7 6.7 14.4 4.9 6.3 10.0 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 PP2C PF00481.16 ETO10656.1 - 8.4e-13 48.2 0.0 1e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C ABC_tran PF00005.22 ETO10658.1 - 1.3e-07 31.9 0.0 3.2e-07 30.7 0.0 1.6 2 0 0 2 2 2 1 ABC transporter Pkinase PF00069.20 ETO10658.1 - 2.5e-07 30.1 0.0 3.2e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO10658.1 - 0.00014 21.0 0.2 0.00022 20.3 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase CBAH PF02275.13 ETO10659.1 - 0.0072 15.7 0.5 0.021 14.2 0.0 1.7 2 0 0 2 2 2 1 Linear amide C-N hydrolases, choloylglycine hydrolase family HpaP PF09483.5 ETO10660.1 - 0.0031 17.4 0.1 0.0044 16.9 0.0 1.1 1 0 0 1 1 1 1 Type III secretion protein (HpaP) Herpes_UL6 PF01763.11 ETO10660.1 - 0.0045 15.2 1.3 0.0051 15.0 0.9 1.1 1 0 0 1 1 1 1 Herpesvirus UL6 like Filament PF00038.16 ETO10660.1 - 0.011 15.1 7.5 0.019 14.4 5.2 1.3 1 0 0 1 1 1 0 Intermediate filament protein CENP-Q PF13094.1 ETO10660.1 - 0.013 15.5 7.0 0.013 15.5 4.9 1.7 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit UPF0242 PF06785.6 ETO10660.1 - 0.014 14.1 4.6 0.022 13.4 3.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) IncA PF04156.9 ETO10660.1 - 0.015 14.8 7.6 0.026 14.1 5.3 1.4 1 0 0 1 1 1 0 IncA protein Reo_sigmaC PF04582.7 ETO10660.1 - 0.016 14.4 1.9 0.023 13.9 1.3 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TBPIP PF07106.8 ETO10660.1 - 0.016 14.7 8.8 0.024 14.2 5.2 1.8 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Laminin_II PF06009.7 ETO10660.1 - 0.017 14.9 3.1 0.035 13.8 2.2 1.6 1 0 0 1 1 1 0 Laminin Domain II DUF1204 PF06721.6 ETO10660.1 - 0.017 14.4 1.4 0.027 13.7 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) CENP-F_leu_zip PF10473.4 ETO10660.1 - 0.021 14.6 8.4 0.021 14.6 5.8 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 ETO10660.1 - 0.062 12.3 7.5 0.09 11.8 5.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 bZIP_1 PF00170.16 ETO10660.1 - 0.067 13.1 9.4 0.57 10.1 2.5 2.6 1 1 1 2 2 2 0 bZIP transcription factor Mod_r PF07200.8 ETO10660.1 - 0.092 12.6 10.1 0.067 13.1 5.7 1.7 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Cep57_MT_bd PF06657.8 ETO10660.1 - 0.093 12.6 4.9 0.18 11.7 3.4 1.4 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Striatin PF08232.7 ETO10660.1 - 0.096 12.9 6.4 0.087 13.1 3.5 1.6 2 0 0 2 2 2 0 Striatin family ADIP PF11559.3 ETO10660.1 - 0.11 12.4 10.9 0.17 11.7 7.5 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF948 PF06103.6 ETO10660.1 - 0.14 11.9 6.3 0.16 11.8 2.6 2.3 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF3450 PF11932.3 ETO10660.1 - 0.23 10.7 8.0 0.36 10.0 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1664 PF07889.7 ETO10660.1 - 0.42 10.4 7.1 0.13 12.0 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CENP-K PF11802.3 ETO10660.1 - 0.59 9.3 9.4 0.19 10.9 4.3 1.7 2 0 0 2 2 2 0 Centromere-associated protein K DUF904 PF06005.7 ETO10660.1 - 0.61 10.4 12.0 0.21 11.9 6.1 2.0 2 1 0 2 2 1 0 Protein of unknown function (DUF904) UPF0449 PF15136.1 ETO10660.1 - 0.74 10.0 7.3 1 9.5 0.5 2.6 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 BLOC1_2 PF10046.4 ETO10660.1 - 0.74 9.9 9.2 1.5 8.9 6.3 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF724 PF05266.9 ETO10660.1 - 0.87 9.1 11.3 0.12 11.9 5.2 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF724) Rho_Binding PF08912.6 ETO10660.1 - 1 9.6 12.6 0.88 9.9 5.6 2.9 3 0 0 3 3 3 0 Rho Binding Phage_GP20 PF06810.6 ETO10660.1 - 1.7 8.0 10.5 0.22 10.9 4.3 1.7 2 0 0 2 2 2 0 Phage minor structural protein GP20 FlaC_arch PF05377.6 ETO10660.1 - 4 7.4 8.0 3.8 7.4 3.2 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) THOC7 PF05615.8 ETO10660.1 - 4 7.6 10.4 2.7 8.2 5.1 2.2 2 1 0 2 2 2 0 Tho complex subunit 7 CCDC92 PF14916.1 ETO10660.1 - 4.7 6.8 11.9 0.21 11.1 2.2 2.3 1 1 1 2 2 2 0 Coiled-coil domain of unknown function Seryl_tRNA_N PF02403.17 ETO10660.1 - 9.8 6.2 11.2 0.74 9.8 3.4 2.3 3 0 0 3 3 2 0 Seryl-tRNA synthetase N-terminal domain Tubulin PF00091.20 ETO10661.1 - 3e-05 23.9 0.3 7e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain TMEM247 PF15444.1 ETO10661.1 - 0.33 10.7 0.0 0.33 10.7 0.0 2.7 3 0 0 3 3 3 0 Transmembrane protein 247 Selenoprotein_S PF06936.6 ETO10661.1 - 1.2 8.6 4.8 0.16 11.4 0.5 1.6 2 0 0 2 2 2 0 Selenoprotein S (SelS) IRK PF01007.15 ETO10662.1 - 1e-17 63.9 0.2 1.7e-17 63.2 0.0 1.3 1 1 0 1 1 1 1 Inward rectifier potassium channel STAS PF01740.16 ETO10663.1 - 1e-18 66.8 0.0 1.9e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain Sulfate_transp PF00916.15 ETO10663.1 - 3.6e-06 26.2 0.3 7.1e-06 25.2 0.2 1.5 1 0 0 1 1 1 1 Sulfate transporter family EST1 PF10374.4 ETO10663.1 - 0.069 13.1 0.1 0.2 11.6 0.0 1.8 1 1 1 2 2 2 0 Telomerase activating protein Est1 Herpes_LMP2 PF07415.6 ETO10664.1 - 0.00074 18.2 0.0 0.001 17.8 0.0 1.1 1 0 0 1 1 1 1 Gammaherpesvirus latent membrane protein (LMP2) protein EF-hand_7 PF13499.1 ETO10665.1 - 0.00069 19.7 0.4 0.0051 16.9 0.1 2.5 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO10665.1 - 0.00082 19.0 0.7 0.013 15.2 0.0 3.3 4 0 0 4 4 4 1 EF-hand domain NUMOD3 PF07460.6 ETO10665.1 - 0.0014 18.4 4.1 0.0029 17.4 2.8 1.5 1 0 0 1 1 1 1 NUMOD3 motif (2 copies) EF-hand_1 PF00036.27 ETO10665.1 - 0.0014 17.7 0.1 0.0072 15.5 0.0 2.3 2 0 0 2 2 2 1 EF hand Myc-LZ PF02344.10 ETO10667.1 - 8.6 6.0 7.9 0.31 10.7 0.3 2.2 2 0 0 2 2 2 0 Myc leucine zipper domain Kinesin PF00225.18 ETO10668.1 - 5.3e-50 170.0 5.5 1e-46 159.1 3.8 3.1 1 1 0 1 1 1 1 Kinesin motor domain DivIC PF04977.10 ETO10668.1 - 0.19 11.2 0.1 0.19 11.2 0.0 3.9 4 1 2 6 6 6 0 Septum formation initiator B56 PF01603.15 ETO10669.1 - 0.0035 15.9 0.0 0.0035 15.9 0.0 2.0 2 0 0 2 2 2 1 Protein phosphatase 2A regulatory B subunit (B56 family) MIP-T3 PF10243.4 ETO10669.1 - 0.012 14.0 31.0 0.014 13.8 21.5 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Utp14 PF04615.8 ETO10669.1 - 0.59 8.2 31.9 0.66 8.0 22.1 1.0 1 0 0 1 1 1 0 Utp14 protein Sin_N PF04801.8 ETO10669.1 - 0.7 8.6 16.7 0.82 8.4 11.6 1.0 1 0 0 1 1 1 0 Sin-like protein conserved region TFIIF_alpha PF05793.7 ETO10669.1 - 0.77 8.0 30.4 0.87 7.8 21.0 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Lin-8 PF03353.10 ETO10669.1 - 1.1 8.5 17.9 1.2 8.3 12.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist eIF-3c_N PF05470.7 ETO10669.1 - 1.3 7.0 19.6 1.6 6.7 13.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF4638 PF15472.1 ETO10669.1 - 1.3 8.5 19.2 1.7 8.1 13.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Peptidase_S64 PF08192.6 ETO10669.1 - 2.5 6.3 24.3 2.8 6.1 16.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 Transformer PF06495.6 ETO10669.1 - 2.6 7.9 8.0 3.7 7.3 5.5 1.3 1 0 0 1 1 1 0 Fruit fly transformer protein DUF966 PF06136.8 ETO10669.1 - 3.7 6.8 27.5 4.1 6.7 19.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) BTV_NS2 PF04514.7 ETO10669.1 - 3.8 6.2 16.3 4.4 6.0 11.3 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF4647 PF15504.1 ETO10669.1 - 8 5.2 21.9 9 5.0 15.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) WD40 PF00400.27 ETO10671.1 - 2.8e-58 191.8 19.9 2.7e-11 42.8 0.1 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO10671.1 - 8.3e-07 27.5 10.3 0.29 9.2 0.0 5.6 1 1 5 6 6 6 5 Nucleoporin Nup120/160 HAD PF12710.2 ETO10671.1 - 0.27 11.3 4.7 1.1e+02 2.9 3.3 3.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase WD40 PF00400.27 ETO10672.1 - 7.7e-12 44.6 0.2 7.7e-06 25.5 0.3 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat PD40 PF07676.7 ETO10672.1 - 0.0079 15.8 0.3 0.13 11.9 0.2 2.3 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Ras PF00071.17 ETO10673.1 - 5.9e-36 123.3 4.3 3.2e-34 117.6 3.0 2.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 ETO10673.1 - 2.5e-15 57.0 0.3 6.2e-15 55.7 0.2 1.7 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO10673.1 - 6.7e-07 28.7 3.7 1.5e-05 24.3 2.6 2.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO10673.1 - 2.9e-05 23.5 0.8 5.9e-05 22.5 0.5 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 ETO10673.1 - 5.2e-05 22.4 1.5 0.00012 21.3 1.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 ETO10673.1 - 0.00055 19.8 0.1 0.0014 18.5 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETO10673.1 - 0.0056 15.9 0.3 0.11 11.7 0.1 2.5 2 1 0 2 2 2 1 Ferrous iron transport protein B ATP_bind_1 PF03029.12 ETO10673.1 - 0.0087 15.6 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 ETO10673.1 - 0.018 14.7 1.7 0.039 13.6 1.2 1.6 1 1 0 1 1 1 0 Archaeal ATPase PseudoU_synth_1 PF01416.15 ETO10673.1 - 0.098 13.0 0.1 0.23 11.9 0.1 1.6 1 0 0 1 1 1 0 tRNA pseudouridine synthase AAA_14 PF13173.1 ETO10673.1 - 0.41 10.5 2.5 2.7 7.9 0.4 2.8 1 1 1 2 2 2 0 AAA domain Menin PF05053.8 ETO10677.1 - 0.056 11.6 1.4 0.055 11.6 1.0 1.1 1 0 0 1 1 1 0 Menin DDHD PF02862.12 ETO10677.1 - 0.059 13.1 1.5 0.077 12.7 1.0 1.1 1 0 0 1 1 1 0 DDHD domain SUZ PF12752.2 ETO10677.1 - 0.097 13.2 1.0 0.17 12.4 0.7 1.4 1 0 0 1 1 1 0 SUZ domain CRT-like PF08627.5 ETO10677.1 - 1 9.2 4.9 0.4 10.6 1.4 1.8 2 1 0 2 2 2 0 CRT-like DNA_repr_REX1B PF14966.1 ETO10678.1 - 0.0085 16.4 0.2 0.062 13.6 0.0 2.1 2 0 0 2 2 2 1 DNA repair REX1-B Ribosomal_S19 PF00203.16 ETO10679.1 - 0.38 10.4 4.3 0.45 10.1 3.0 1.1 1 0 0 1 1 1 0 Ribosomal protein S19 SR-25 PF10500.4 ETO10679.1 - 1.6 8.1 15.9 1.6 8.1 11.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF148 PF02520.12 ETO10681.1 - 0.038 13.7 3.8 0.039 13.7 1.8 1.6 2 0 0 2 2 2 0 Domain of unknown function DUF148 DUF1151 PF06625.6 ETO10681.1 - 2 8.1 7.6 4.8 6.9 4.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1151) DUF485 PF04341.7 ETO10682.1 - 0.022 14.4 0.8 0.022 14.4 0.5 2.9 3 1 1 4 4 4 0 Protein of unknown function, DUF485 UcrQ PF02939.11 ETO10682.1 - 0.089 12.6 0.4 0.089 12.6 0.3 3.6 3 2 0 4 4 4 0 UcrQ family BatA PF07584.6 ETO10682.1 - 0.098 12.8 5.4 1.6 8.9 0.0 3.7 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal PLRV_ORF5 PF01690.12 ETO10686.1 - 0.53 9.3 5.0 0.64 9.1 3.5 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF2043 PF09740.4 ETO10686.1 - 1.9 8.5 5.3 0.88 9.6 0.4 2.5 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2043) WD40 PF00400.27 ETO10687.1 - 6.8e-44 146.2 9.6 5.7e-11 41.8 0.6 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO10687.1 - 8.2e-08 30.8 5.9 0.025 12.7 0.3 4.0 1 1 3 4 4 4 4 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO10687.1 - 6.7e-05 22.6 0.3 0.47 10.2 0.0 4.0 1 1 2 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Kelch_6 PF13964.1 ETO10690.1 - 0.00017 21.6 7.9 1.9 8.7 0.1 5.8 6 1 0 6 6 6 2 Kelch motif Kelch_4 PF13418.1 ETO10690.1 - 0.0026 17.5 1.6 2 8.2 0.1 4.6 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO10690.1 - 0.0051 16.3 0.5 3.2 7.3 0.0 4.2 5 0 0 5 5 5 1 Kelch motif ACOX PF01756.14 ETO10692.1 - 5.1e-05 22.7 0.9 8.9e-05 21.9 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA oxidase Bacillus_HBL PF05791.6 ETO10693.1 - 0.11 11.8 19.3 0.02 14.2 10.7 1.8 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) IncA PF04156.9 ETO10693.1 - 0.14 11.7 14.4 0.28 10.7 10.0 1.5 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 ETO10693.1 - 0.21 9.4 12.9 0.29 8.9 8.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPV_P10 PF05531.7 ETO10693.1 - 1.3 9.3 9.7 3.4 7.9 2.7 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.1 ETO10693.1 - 6.9 5.5 6.7 12 4.7 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.7 ETO10693.1 - 8.9 6.1 12.6 0.43 10.3 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Kelch_6 PF13964.1 ETO10694.1 - 0.00032 20.7 2.8 0.88 9.8 0.0 4.2 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO10694.1 - 0.011 15.4 1.9 3.2 7.6 0.0 4.7 5 0 0 5 5 5 0 Kelch motif Kelch_1 PF01344.20 ETO10694.1 - 0.077 12.5 4.6 3.3 7.3 0.0 4.3 4 1 0 4 4 4 0 Kelch motif Kelch_5 PF13854.1 ETO10694.1 - 0.61 10.1 4.7 1.2 9.2 0.0 3.3 4 0 0 4 4 4 0 Kelch motif WD40 PF00400.27 ETO10695.1 - 5.2e-60 197.3 27.2 1.1e-12 47.3 0.6 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO10695.1 - 2.5e-10 39.1 4.8 0.19 9.8 0.0 5.2 2 2 3 5 5 5 5 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO10695.1 - 0.00011 22.1 12.2 0.053 13.7 0.1 5.4 5 1 0 5 5 5 1 Kelch motif PQQ_2 PF13360.1 ETO10695.1 - 0.0022 17.5 0.5 0.018 14.4 0.1 2.7 1 1 0 1 1 1 1 PQQ-like domain CheF-arch PF04283.7 ETO10696.1 - 0.01 15.0 0.4 0.022 13.9 0.1 1.7 2 1 0 2 2 2 0 Chemotaxis signal transduction system protein F from archaea PH PF00169.24 ETO10696.1 - 0.02 15.0 1.7 1.4 9.1 0.0 2.4 3 0 0 3 3 3 0 PH domain Neur_chan_memb PF02932.11 ETO10697.1 - 0.00012 22.1 7.0 0.00012 22.1 4.9 3.3 2 2 1 3 3 3 1 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.10 ETO10697.1 - 0.0073 14.9 0.5 0.009 14.6 0.3 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein FAM178 PF14816.1 ETO10697.1 - 0.32 9.6 3.5 0.68 8.5 2.4 1.5 1 0 0 1 1 1 0 Family of unknown function, FAM178 CDC45 PF02724.9 ETO10697.1 - 0.7 7.8 13.6 0.074 11.0 5.0 1.9 2 0 0 2 2 2 0 CDC45-like protein Pox_Ag35 PF03286.9 ETO10697.1 - 4.7 6.6 20.7 0.53 9.7 11.2 1.6 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF805 PF05656.9 ETO10697.1 - 6.5 6.6 10.7 0.39 10.5 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF805) ORC6 PF05460.8 ETO10698.1 - 1.1 8.2 10.9 1.4 7.9 7.6 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) RCC1 PF00415.13 ETO10699.1 - 7.7e-23 80.4 0.3 2.2e-05 24.5 0.0 7.2 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO10699.1 - 0.0013 18.2 14.7 0.0048 16.4 0.2 4.0 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat SQS_PSY PF00494.14 ETO10702.1 - 0.0057 15.9 0.0 0.0099 15.1 0.0 1.4 1 0 0 1 1 1 1 Squalene/phytoene synthase GDI PF00996.13 ETO10703.1 - 1.1e-45 155.7 6.5 2.6e-23 82.0 0.8 3.9 3 1 1 4 4 4 4 GDP dissociation inhibitor Raftlin PF15250.1 ETO10704.1 - 0.033 12.7 0.8 0.042 12.3 0.6 1.0 1 0 0 1 1 1 0 Raftlin PWWP PF00855.12 ETO10704.1 - 0.12 12.6 0.5 0.19 11.9 0.3 1.5 1 1 0 1 1 1 0 PWWP domain GTP_EFTU PF00009.22 ETO10705.1 - 1.4e-26 93.1 0.0 1.6e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 ETO10705.1 - 4.4e-07 29.8 0.0 1e-06 28.7 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 ETO10705.1 - 1.4e-05 25.5 0.1 4.1e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein AAA_18 PF13238.1 ETO10705.1 - 0.0012 19.1 0.0 0.002 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 ETO10705.1 - 0.0022 17.8 1.7 0.55 10.0 0.4 2.3 1 1 1 2 2 2 2 Dynamin family Zeta_toxin PF06414.7 ETO10705.1 - 0.0023 17.0 0.1 0.0081 15.2 0.0 1.9 1 1 1 2 2 2 1 Zeta toxin DUF258 PF03193.11 ETO10705.1 - 0.0052 15.9 0.2 0.011 14.9 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 ETO10705.1 - 0.013 14.9 0.1 3.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 ETO10705.1 - 0.018 14.0 0.0 0.04 12.9 0.0 1.5 1 1 0 1 1 1 0 Septin AAA_17 PF13207.1 ETO10705.1 - 0.03 15.1 0.3 0.046 14.5 0.2 1.7 1 1 0 1 1 1 0 AAA domain Arf PF00025.16 ETO10705.1 - 0.044 13.0 0.1 1 8.5 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_16 PF13191.1 ETO10705.1 - 0.076 13.0 0.1 0.14 12.1 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 ETO10705.1 - 0.097 12.2 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 ETO10705.1 - 0.11 12.7 0.1 0.18 12.1 0.1 1.5 1 1 0 1 1 1 0 ABC transporter cobW PF02492.14 ETO10705.1 - 0.12 11.7 0.1 0.2 11.0 0.0 1.4 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain WD40 PF00400.27 ETO10709.1 - 1.3e-10 40.6 0.1 1.8e-07 30.7 0.1 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat Sporozoite_P67 PF05642.6 ETO10709.1 - 0.14 10.0 11.5 0.2 9.4 8.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RNase_H PF00075.19 ETO10710.1 - 7e-07 29.6 0.0 1.9e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.1 ETO10710.1 - 0.054 13.2 0.1 0.18 11.6 0.1 1.9 1 1 0 1 1 1 0 Reverse transcriptase-like SapB_1 PF05184.10 ETO10710.1 - 0.065 13.0 1.6 25 4.8 0.1 3.8 4 0 0 4 4 4 0 Saposin-like type B, region 1 RPAP1_N PF08621.5 ETO10710.1 - 0.079 12.5 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 RPAP1-like, N-terminal WD40 PF00400.27 ETO10711.1 - 2e-07 30.6 0.0 0.00036 20.2 0.0 4.3 4 0 0 4 4 4 1 WD domain, G-beta repeat PD40 PF07676.7 ETO10711.1 - 6.9e-07 28.8 1.7 0.01 15.4 0.0 5.0 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat DUF2716 PF10898.3 ETO10711.1 - 0.021 14.8 0.1 0.079 12.9 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2716) MBT PF02820.13 ETO10713.1 - 0.00023 21.0 0.0 0.00085 19.1 0.0 2.0 1 0 0 1 1 1 1 mbt repeat ERp29 PF07749.7 ETO10714.1 - 7.9e-19 68.0 1.6 1.6e-18 67.0 1.1 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain ERp29_N PF07912.8 ETO10714.1 - 5.2e-16 58.7 0.9 1.2e-15 57.5 0.1 1.9 2 0 0 2 2 2 1 ERp29, N-terminal domain HrpB2 PF09487.5 ETO10714.1 - 0.08 13.1 0.2 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) Mito_carr PF00153.22 ETO10715.1 - 7.1e-27 92.9 0.6 3.8e-15 55.3 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF4393 PF14337.1 ETO10716.1 - 0.038 13.4 1.2 0.051 13.0 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4393) PTPlike_phytase PF14566.1 ETO10716.1 - 0.3 11.1 3.5 0.45 10.5 2.4 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate YebO PF13974.1 ETO10716.1 - 1.4 8.7 9.4 3.7 7.3 6.5 1.8 1 1 0 1 1 1 0 YebO-like protein Bap31 PF05529.7 ETO10716.1 - 3.7 6.9 8.0 6.3 6.1 5.5 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Fib_alpha PF08702.5 ETO10716.1 - 7.4 6.6 13.1 7.5 6.6 0.7 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family adh_short PF00106.20 ETO10717.1 - 2.8e-23 82.6 0.0 3.5e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETO10717.1 - 4.4e-13 49.5 0.0 5.7e-13 49.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETO10717.1 - 1.6e-06 27.9 0.0 2.2e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 KR domain TFIIS_M PF07500.9 ETO10718.1 - 6.1e-14 52.0 4.1 9e-14 51.5 2.8 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain Med26 PF08711.6 ETO10719.1 - 7.8e-13 47.7 0.3 7.8e-13 47.7 0.2 2.1 3 0 0 3 3 3 1 TFIIS helical bundle-like domain LEDGF PF11467.3 ETO10719.1 - 0.0031 17.1 1.3 0.0045 16.6 0.9 1.3 1 0 0 1 1 1 1 Lens epithelium-derived growth factor (LEDGF) ResIII PF04851.10 ETO10719.1 - 0.059 13.2 1.7 0.08 12.7 1.2 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF4636 PF15468.1 ETO10720.1 - 0.0074 15.7 0.2 0.009 15.4 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4636) Nodulin_late PF07127.6 ETO10720.1 - 0.034 14.2 4.0 0.35 11.0 0.1 2.3 2 0 0 2 2 2 0 Late nodulin protein ETRAMP PF09716.5 ETO10720.1 - 0.14 12.1 6.6 7.5 6.5 4.6 2.2 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Glyco_hydro_9 PF00759.14 ETO10721.1 - 0.11 11.3 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 V-SNARE_C PF12352.3 ETO10722.1 - 3.7e-05 23.7 4.5 3.7e-05 23.7 3.1 2.0 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 ETO10722.1 - 0.00025 20.7 3.8 0.0003 20.4 0.2 2.7 2 1 2 4 4 4 1 Sec20 V-SNARE PF05008.10 ETO10722.1 - 0.031 14.4 2.3 0.098 12.8 1.5 2.0 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus DUF2321 PF10083.4 ETO10722.1 - 0.045 13.2 0.9 2.1 7.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Syntaxin-6_N PF09177.6 ETO10722.1 - 0.17 12.3 9.5 2.8 8.4 0.5 2.6 1 1 2 3 3 3 0 Syntaxin 6, N-terminal TcdB_N PF12918.2 ETO10722.1 - 0.18 11.9 4.2 0.42 10.7 2.0 2.3 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain DUF3439 PF11921.3 ETO10723.1 - 0.25 11.0 17.7 0.41 10.4 2.3 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF4064 PF13273.1 ETO10724.1 - 0.018 15.1 0.4 4.4 7.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) EF-hand_8 PF13833.1 ETO10725.1 - 1.1e-10 40.9 1.5 2.8e-05 23.6 0.0 3.5 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_7 PF13499.1 ETO10725.1 - 7.7e-09 35.5 1.3 0.0011 19.0 0.1 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO10725.1 - 1.1e-08 34.2 1.4 0.013 15.3 0.1 3.8 3 1 1 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 ETO10725.1 - 2.4e-06 26.4 6.9 0.0084 15.3 0.5 3.5 4 0 0 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.4 ETO10725.1 - 1.1e-05 25.4 0.8 0.0015 18.5 0.1 2.4 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.1 ETO10725.1 - 2.1e-05 23.6 1.1 0.00079 18.6 0.0 3.0 3 0 0 3 3 3 1 EF hand EF-hand_4 PF12763.2 ETO10725.1 - 0.00022 20.9 0.4 0.011 15.4 0.0 2.2 1 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand LTXXQ PF07813.7 ETO10725.1 - 0.00033 21.0 0.6 0.00064 20.1 0.2 1.7 2 0 0 2 2 2 1 LTXXQ motif family protein Toprim_2 PF13155.1 ETO10725.1 - 0.00081 19.6 0.1 0.0015 18.8 0.0 1.4 1 0 0 1 1 1 1 Toprim-like EF-hand_9 PF14658.1 ETO10725.1 - 0.013 15.4 0.2 0.11 12.4 0.0 2.4 2 1 1 3 3 3 0 EF-hand domain Cnd1 PF12717.2 ETO10727.1 - 0.00039 20.3 3.7 0.018 14.8 0.9 2.2 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 ETO10727.1 - 0.00043 20.5 0.0 1.1 9.6 0.0 2.5 2 1 0 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 ETO10727.1 - 0.0028 18.1 0.0 3.4 8.2 0.0 3.4 4 0 0 4 4 4 2 HEAT-like repeat HEAT PF02985.17 ETO10727.1 - 0.0042 17.0 0.5 2.7 8.2 0.0 3.5 4 0 0 4 4 4 2 HEAT repeat IncA PF04156.9 ETO10730.1 - 0.12 11.9 0.5 0.17 11.4 0.3 1.2 1 0 0 1 1 1 0 IncA protein TMEM51 PF15345.1 ETO10732.1 - 0.023 14.3 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Herpes_US9 PF06072.6 ETO10732.1 - 0.94 9.3 4.8 0.59 10.0 0.2 2.2 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 LAGLIDADG_1 PF00961.14 ETO10733.1 - 0.091 13.3 3.9 0.92 10.0 2.7 2.1 1 1 0 1 1 1 0 LAGLIDADG endonuclease Pep3_Vps18 PF05131.9 ETO10734.1 - 0.067 12.6 0.2 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Pep3/Vps18/deep orange family NAD_binding_9 PF13454.1 ETO10734.1 - 0.094 12.4 0.1 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 FAD-NAD(P)-binding C1_4 PF07975.7 ETO10734.1 - 0.12 12.3 1.4 0.12 12.3 0.1 1.7 2 0 0 2 2 2 0 TFIIH C1-like domain Mur_ligase_C PF02875.16 ETO10738.1 - 0.00084 19.3 0.0 0.0019 18.1 0.0 1.6 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Peptidase_C14 PF00656.17 ETO10739.1 - 8.3e-14 51.8 1.1 1.2e-13 51.3 0.7 1.2 1 0 0 1 1 1 1 Caspase domain Phage_int_SAM_4 PF13495.1 ETO10739.1 - 0.0092 16.2 0.2 0.02 15.2 0.1 1.5 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain TPR_12 PF13424.1 ETO10740.1 - 1.1e-66 220.7 20.0 2.6e-22 78.5 1.2 4.5 2 1 1 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO10740.1 - 7.1e-49 161.5 44.9 1.8e-08 33.6 0.2 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_10 PF13374.1 ETO10740.1 - 1e-48 161.8 0.2 6.9e-10 38.5 0.0 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_11 PF13414.1 ETO10740.1 - 1.7e-43 146.1 25.7 1.7e-14 53.1 0.2 5.1 4 1 1 5 5 5 4 TPR repeat TPR_7 PF13176.1 ETO10740.1 - 2.9e-43 142.2 18.9 4.8e-07 29.0 0.0 7.3 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 ETO10740.1 - 1.3e-37 124.7 32.2 2.8e-06 26.8 0.7 6.9 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETO10740.1 - 9.6e-34 112.6 50.3 6e-07 28.8 3.0 7.9 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 ETO10740.1 - 5.1e-18 65.2 1.1 1.2e-05 25.7 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO10740.1 - 5.5e-18 63.8 0.0 0.5 11.1 0.0 6.6 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 ETO10740.1 - 1.7e-16 58.9 18.9 0.02 15.0 0.2 7.9 8 1 0 8 8 6 5 Tetratricopeptide repeat TPR_6 PF13174.1 ETO10740.1 - 4.1e-11 42.5 9.0 0.076 13.5 0.2 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO10740.1 - 2.3e-08 33.1 2.9 2.3 7.5 0.1 6.2 6 0 0 6 6 6 2 SHNi-TPR MIT PF04212.13 ETO10740.1 - 6.5e-08 32.3 28.4 0.24 11.2 0.3 6.8 7 0 0 7 7 6 4 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 ETO10740.1 - 4.6e-07 29.8 20.1 0.0081 16.2 4.1 4.7 1 1 4 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 ETO10740.1 - 2.5e-06 27.2 23.9 0.013 15.3 0.3 6.1 6 0 0 6 6 6 2 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.1 ETO10740.1 - 6.3e-06 26.4 11.1 0.16 12.3 0.1 4.5 1 1 4 5 5 5 4 Tetratricopeptide repeat DUF2225 PF09986.4 ETO10740.1 - 6.6e-06 25.7 17.4 0.036 13.5 0.5 3.5 2 1 1 3 3 3 3 Uncharacterized protein conserved in bacteria (DUF2225) PPR PF01535.15 ETO10740.1 - 0.00012 21.7 8.9 0.31 11.0 0.0 5.8 6 0 0 6 6 5 1 PPR repeat Ten1_2 PF15490.1 ETO10740.1 - 0.0018 17.8 0.1 14 5.3 0.0 4.1 2 2 2 4 4 4 0 Telomere-capping, CST complex subunit DUF3568 PF12092.3 ETO10740.1 - 0.0067 16.1 2.1 16 5.1 0.0 4.3 1 1 2 4 4 4 0 Protein of unknown function (DUF3568) DUF627 PF04781.7 ETO10740.1 - 0.0082 15.7 14.8 5.2 6.7 0.0 6.0 3 2 3 6 6 6 1 Protein of unknown function (DUF627) Sel1 PF08238.7 ETO10740.1 - 0.012 16.2 17.4 4.4 8.0 0.5 6.1 6 0 0 6 6 6 0 Sel1 repeat DUF2977 PF11192.3 ETO10740.1 - 0.016 15.0 0.1 25 4.8 0.0 3.9 4 0 0 4 4 3 0 Protein of unknown function (DUF2977) DUF3856 PF12968.2 ETO10740.1 - 0.021 14.6 5.3 5.1 6.9 0.1 4.1 1 1 3 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_3 PF07720.7 ETO10740.1 - 0.042 13.6 33.2 1.3 8.8 0.1 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat RPN7 PF10602.4 ETO10740.1 - 0.12 11.7 17.6 1.5 8.1 1.7 4.6 1 1 1 4 4 4 0 26S proteasome subunit RPN7 Musclin PF11037.3 ETO10740.1 - 0.13 11.8 0.0 48 3.5 0.0 3.9 4 0 0 4 4 4 0 Insulin-resistance promoting peptide in skeletal muscle DUF3450 PF11932.3 ETO10740.1 - 0.31 10.2 1.9 0.68 9.1 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) WD40 PF00400.27 ETO10741.1 - 1e-15 56.9 3.7 1.2e-07 31.2 0.1 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO10741.1 - 0.032 12.3 0.2 1 7.4 0.0 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO10741.1 - 0.079 11.6 0.4 2.9 6.5 0.0 2.0 1 1 1 2 2 2 0 Nup133 N terminal like RPEL PF02755.10 ETO10742.1 - 1.1e-05 24.6 21.8 0.00031 19.9 0.5 5.8 6 1 0 6 6 6 3 RPEL repeat DUF2608 PF11019.3 ETO10742.1 - 0.0072 15.3 2.1 0.0072 15.3 1.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2608) RPEL PF02755.10 ETO10743.1 - 5.8e-05 22.2 13.8 0.14 11.5 0.9 5.1 5 0 0 5 5 5 3 RPEL repeat Urm1 PF09138.6 ETO10743.1 - 0.07 13.2 0.0 0.51 10.4 0.0 2.5 1 1 0 1 1 1 0 Urm1 (Ubiquitin related modifier) Zip PF02535.17 ETO10743.1 - 0.52 9.2 4.4 3.5 6.5 3.2 1.9 1 1 0 1 1 1 0 ZIP Zinc transporter Ank_2 PF12796.2 ETO10744.1 - 0.031 14.6 0.1 0.059 13.7 0.1 1.8 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) DUF417 PF04224.7 ETO10744.1 - 0.099 11.9 4.6 0.14 11.5 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF417 TIM21 PF08294.6 ETO10744.1 - 0.49 10.0 0.0 0.49 10.0 0.0 2.1 2 0 0 2 2 2 0 TIM21 DUF912 PF06024.7 ETO10744.1 - 0.75 9.8 4.1 3.2 7.8 1.3 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) T2SF PF00482.18 ETO10744.1 - 1.4 8.8 6.5 1.3 8.9 3.3 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F PARP PF00644.15 ETO10745.1 - 0.046 13.1 0.2 0.1 12.0 0.1 1.5 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain G-alpha PF00503.15 ETO10746.1 - 6.8e-24 84.2 0.5 8.9e-24 83.8 0.3 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO10746.1 - 0.035 13.3 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_28 PF13521.1 ETO10746.1 - 0.037 14.0 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 ETO10746.1 - 0.039 13.4 0.0 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_18 PF13238.1 ETO10746.1 - 0.042 14.1 1.3 0.051 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 ETO10746.1 - 0.063 13.5 0.1 0.091 13.0 0.1 1.3 1 0 0 1 1 1 0 ABC transporter RNA_pol_Rpb1_3 PF04983.13 ETO10746.1 - 0.068 12.9 0.1 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 3 MMR_HSR1 PF01926.18 ETO10746.1 - 0.074 13.0 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.1 ETO10746.1 - 0.079 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain RPAP3_C PF13877.1 ETO10748.1 - 0.011 15.6 0.9 0.53 10.2 0.2 2.1 1 1 1 2 2 2 0 Potential Monad-binding region of RPAP3 AhpC-TSA PF00578.16 ETO10748.1 - 0.059 13.0 0.0 0.08 12.6 0.0 1.3 1 1 0 1 1 1 0 AhpC/TSA family Vezatin PF12632.2 ETO10748.1 - 0.12 11.4 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes Y_phosphatase3C PF13348.1 ETO10748.1 - 0.15 12.1 0.1 2.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Tyrosine phosphatase family C-terminal region Pox_E10 PF04805.7 ETO10749.1 - 0.024 14.1 0.5 0.088 12.3 0.1 2.1 2 0 0 2 2 2 0 E10-like protein conserved region AAA_16 PF13191.1 ETO10749.1 - 0.026 14.4 0.1 0.44 10.5 0.0 2.7 2 1 1 3 3 3 0 AAA ATPase domain NTPase_1 PF03266.10 ETO10749.1 - 0.089 12.5 0.1 7.1 6.3 0.0 2.7 2 0 0 2 2 2 0 NTPase Malic_M PF03949.10 ETO10750.1 - 2.4e-25 89.5 0.1 3e-25 89.2 0.1 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain NAAA-beta PF15508.1 ETO10751.1 - 3.5e-20 72.1 0.1 4.9e-20 71.6 0.1 1.2 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase CBAH PF02275.13 ETO10751.1 - 0.00064 19.2 0.0 0.00089 18.7 0.0 1.2 1 0 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family DDE_Tnp_1_3 PF13612.1 ETO10752.1 - 0.13 12.0 1.6 5.7 6.6 0.0 2.1 1 1 1 2 2 2 0 Transposase DDE domain DUF4199 PF13858.1 ETO10753.1 - 0.00038 20.4 0.1 0.045 13.6 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4199) Peroxin-13_N PF04088.8 ETO10753.1 - 0.0013 18.7 1.0 0.0013 18.7 0.7 2.1 1 1 1 2 2 2 1 Peroxin 13, N-terminal region Zip PF02535.17 ETO10753.1 - 0.0019 17.2 0.3 0.0023 17.0 0.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Ycf1 PF05758.7 ETO10753.1 - 0.0046 14.7 9.4 0.005 14.6 6.5 1.0 1 0 0 1 1 1 1 Ycf1 Mem_trans PF03547.13 ETO10753.1 - 0.0079 14.5 1.0 0.0081 14.5 0.7 1.0 1 0 0 1 1 1 1 Membrane transport protein DUF1510 PF07423.6 ETO10753.1 - 0.012 15.0 14.4 0.015 14.7 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Menin PF05053.8 ETO10753.1 - 0.012 13.8 4.4 0.014 13.5 3.1 1.0 1 0 0 1 1 1 0 Menin DUF912 PF06024.7 ETO10753.1 - 0.034 14.1 0.7 0.034 14.1 0.5 2.4 1 1 2 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SID-1_RNA_chan PF13965.1 ETO10753.1 - 0.036 12.2 1.9 0.041 12.0 1.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.11 ETO10753.1 - 0.039 13.8 1.2 0.043 13.7 0.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2207 PF09972.4 ETO10753.1 - 0.22 10.0 4.0 0.25 9.8 2.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) NPR3 PF03666.8 ETO10753.1 - 0.47 8.9 14.2 0.58 8.6 9.8 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Sec62 PF03839.11 ETO10753.1 - 0.55 9.5 16.9 0.69 9.2 11.7 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 SpoIIP PF07454.6 ETO10753.1 - 0.62 9.1 12.3 0.86 8.7 8.5 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF262 PF03235.9 ETO10753.1 - 0.69 9.8 8.8 0.79 9.6 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 7tm_1 PF00001.16 ETO10753.1 - 0.84 8.7 6.8 11 5.0 4.7 2.1 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) AAA_11 PF13086.1 ETO10753.1 - 0.9 9.0 6.9 1.2 8.6 4.8 1.2 1 0 0 1 1 1 0 AAA domain DUF3513 PF12026.3 ETO10753.1 - 1.7 8.1 8.5 2.4 7.6 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) RP-C_C PF11800.3 ETO10753.1 - 1.8 8.1 7.4 2.5 7.7 5.2 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF2413 PF10310.4 ETO10753.1 - 2 7.1 14.1 2.2 6.9 9.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF3987 PF13148.1 ETO10753.1 - 2.1 6.8 12.8 2.6 6.5 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Vfa1 PF08432.5 ETO10753.1 - 3.5 7.6 21.9 4.5 7.2 15.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Ctr PF04145.10 ETO10753.1 - 4 7.4 6.5 16 5.4 4.5 1.9 1 1 0 1 1 1 0 Ctr copper transporter family DRY_EERY PF09750.4 ETO10753.1 - 4.6 7.3 10.8 6 6.9 7.5 1.2 1 0 0 1 1 1 0 Alternative splicing regulator Phlebovirus_NSM PF07246.6 ETO10753.1 - 6 5.9 14.8 7.4 5.6 10.3 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF1168 PF06658.7 ETO10753.1 - 8.4 5.9 37.3 11 5.5 25.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) CCDC71L PF15374.1 ETO10753.1 - 9.6 5.4 18.1 11 5.1 12.5 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L RCSD PF05177.7 ETO10754.1 - 0.47 10.9 16.0 0.14 12.7 7.4 2.2 1 1 1 2 2 2 0 RCSD region MIP-T3 PF10243.4 ETO10755.1 - 1.9e-05 23.3 13.9 2e-05 23.2 9.6 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Tim54 PF11711.3 ETO10755.1 - 0.0064 15.1 7.2 0.0089 14.6 5.0 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Neur_chan_memb PF02932.11 ETO10755.1 - 0.097 12.5 2.0 0.15 11.8 1.4 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.17 ETO10755.1 - 0.099 11.6 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.9 ETO10755.1 - 0.27 9.2 5.4 0.32 8.9 3.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2126 PF09899.4 ETO10755.1 - 0.27 9.2 3.0 0.38 8.7 1.8 1.3 2 0 0 2 2 2 0 Putative amidoligase enzyme (DUF2126) SUFU_C PF12470.3 ETO10755.1 - 0.37 10.3 4.9 0.61 9.6 3.4 1.4 1 1 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain DUF4220 PF13968.1 ETO10755.1 - 0.5 9.4 2.0 0.82 8.7 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) LicD PF04991.8 ETO10755.1 - 0.68 9.9 10.8 1.1 9.3 7.5 1.3 1 0 0 1 1 1 0 LicD family OmpH PF03938.9 ETO10755.1 - 1.4 8.8 15.3 2.1 8.2 10.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3807 PF12720.2 ETO10755.1 - 1.5 8.9 19.4 2.5 8.2 13.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DDHD PF02862.12 ETO10755.1 - 2.3 7.9 11.9 3.8 7.2 8.2 1.3 1 0 0 1 1 1 0 DDHD domain AAA_13 PF13166.1 ETO10755.1 - 3.8 5.8 22.5 5.1 5.4 15.6 1.1 1 0 0 1 1 1 0 AAA domain DUF2201_N PF13203.1 ETO10755.1 - 4.8 6.2 7.0 6.4 5.8 4.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF2058 PF09831.4 ETO10755.1 - 6.7 6.5 23.3 10 6.0 16.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Vfa1 PF08432.5 ETO10755.1 - 7.5 6.5 27.5 13 5.7 19.1 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Melibiase PF02065.13 ETO10756.1 - 0.0001 21.1 0.8 0.0011 17.7 0.0 2.4 3 0 0 3 3 3 1 Melibiase FimH_man-bind PF09160.5 ETO10756.1 - 0.042 13.6 0.6 0.077 12.8 0.4 1.4 1 0 0 1 1 1 0 FimH, mannose binding OPA3 PF07047.7 ETO10758.1 - 4.2e-10 39.5 4.0 9.8e-10 38.3 0.7 2.1 2 0 0 2 2 2 1 Optic atrophy 3 protein (OPA3) Syntaxin-6_N PF09177.6 ETO10758.1 - 0.0035 17.7 2.9 1.7 9.1 0.0 3.0 3 0 0 3 3 3 1 Syntaxin 6, N-terminal Halogen_Hydrol PF10112.4 ETO10758.1 - 0.033 13.5 0.6 0.21 10.9 0.0 2.0 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Uds1 PF15456.1 ETO10758.1 - 0.08 12.9 0.3 0.19 11.6 0.2 1.6 1 1 0 1 1 1 0 Up-regulated During Septation FlxA PF14282.1 ETO10758.1 - 0.083 12.8 13.0 0.076 12.9 0.8 2.7 1 1 1 2 2 2 0 FlxA-like protein DUF4349 PF14257.1 ETO10758.1 - 0.11 11.7 1.3 0.44 9.7 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) DUF972 PF06156.8 ETO10758.1 - 0.12 12.7 1.8 6.5 7.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Seryl_tRNA_N PF02403.17 ETO10758.1 - 0.15 12.0 2.2 2.8 7.9 0.2 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.7 ETO10758.1 - 0.2 11.9 2.0 5.4 7.3 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.10 ETO10758.1 - 0.2 11.1 8.4 5.2 6.6 0.7 3.7 3 1 0 3 3 3 0 Septum formation initiator DUF2968 PF11180.3 ETO10758.1 - 0.29 10.4 3.9 1.1 8.6 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) IncA PF04156.9 ETO10758.1 - 0.46 10.0 4.8 5 6.6 2.8 2.1 1 1 0 1 1 1 0 IncA protein Prefoldin_2 PF01920.15 ETO10758.1 - 1.9 8.2 8.8 4.6 7.0 1.6 2.7 3 0 0 3 3 3 0 Prefoldin subunit SlyX PF04102.7 ETO10758.1 - 2.5 8.5 5.7 3.6 8.0 0.1 2.7 3 0 0 3 3 3 0 SlyX DUF4200 PF13863.1 ETO10758.1 - 4.2 7.3 9.0 6.2 6.7 1.8 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Fib_alpha PF08702.5 ETO10758.1 - 6.8 6.7 8.3 2.6 8.1 3.0 2.0 2 1 1 3 3 2 0 Fibrinogen alpha/beta chain family HC2 PF07382.6 ETO10759.1 - 1.6e-07 31.3 34.0 2.6e-07 30.6 23.5 1.3 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 ASFV_J13L PF05568.6 ETO10759.1 - 8.3e-06 25.4 13.2 0.0013 18.3 3.1 2.4 1 1 1 2 2 2 2 African swine fever virus J13L protein XPG_I PF00867.13 ETO10760.1 - 5e-30 103.4 0.2 1.2e-29 102.2 0.1 1.6 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 ETO10760.1 - 1.1e-09 38.3 0.1 4e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold XPG_N PF00752.12 ETO10760.1 - 2.4e-07 30.9 0.0 6.2e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain DUF2996 PF11210.3 ETO10760.1 - 0.03 14.5 0.1 0.052 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2996) HHH_2 PF12826.2 ETO10760.1 - 0.041 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif HSDR_N_2 PF13588.1 ETO10760.1 - 0.049 13.4 0.1 12 5.6 0.0 2.9 3 0 0 3 3 3 0 Type I restriction enzyme R protein N terminus (HSDR_N) UBA_2 PF08587.6 ETO10760.1 - 0.089 12.9 0.0 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) HXXSHH PF07586.6 ETO10760.1 - 0.49 9.2 3.4 0.12 11.2 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1552) RRM_6 PF14259.1 ETO10761.1 - 8.4e-15 54.5 0.0 1.4e-06 28.1 0.0 2.5 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO10761.1 - 3.1e-07 29.9 0.0 0.015 14.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO10761.1 - 0.0048 16.7 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF912 PF06024.7 ETO10761.1 - 0.055 13.5 0.1 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) RRM_6 PF14259.1 ETO10762.1 - 3e-12 46.3 0.6 0.017 15.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO10762.1 - 7.2e-10 38.3 1.0 0.037 13.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YscJ_FliF PF01514.12 ETO10762.1 - 0.0078 15.3 0.0 0.21 10.7 0.0 2.0 2 0 0 2 2 2 1 Secretory protein of YscJ/FliF family DUF1644 PF07800.7 ETO10763.1 - 0.00098 19.0 10.4 0.0021 17.9 7.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1644) DUF1796 PF08795.5 ETO10763.1 - 0.0063 16.1 0.4 0.0091 15.6 0.3 1.2 1 0 0 1 1 1 1 Putative papain-like cysteine peptidase (DUF1796) RNA_pol_Rpc82 PF05645.8 ETO10763.1 - 0.024 14.1 1.2 0.033 13.7 0.8 1.2 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 DUF2452 PF10504.4 ETO10763.1 - 0.042 13.1 1.0 0.077 12.2 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) TnpV PF14198.1 ETO10763.1 - 0.047 13.5 0.3 0.11 12.3 0.2 1.7 1 0 0 1 1 1 0 Transposon-encoded protein TnpV zf-RING-like PF08746.6 ETO10763.1 - 2.4 8.2 9.5 2.5 8.1 4.6 2.6 2 1 1 3 3 3 0 RING-like domain DNA_PPF PF02916.10 ETO10764.1 - 4.9 7.2 12.9 3.4 7.7 3.6 2.3 1 1 1 2 2 2 0 DNA polymerase processivity factor PrgI PF12666.2 ETO10765.1 - 0.88 9.7 11.3 0.045 13.8 1.5 3.0 3 1 1 4 4 4 0 PrgI family protein Vpu PF00558.14 ETO10765.1 - 9 5.9 8.8 13 5.4 1.0 2.6 2 0 0 2 2 2 0 Vpu protein DEP PF00610.16 ETO10766.1 - 0.0042 16.7 0.0 0.0083 15.8 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PP2C PF00481.16 ETO10767.1 - 6.7e-11 42.0 0.1 2.7e-10 40.1 0.0 2.1 2 1 0 2 2 2 1 Protein phosphatase 2C FimP PF09766.4 ETO10768.1 - 0.0017 17.5 0.2 0.0017 17.4 0.1 1.0 1 0 0 1 1 1 1 Fms-interacting protein Anoctamin PF04547.7 ETO10768.1 - 0.0095 14.6 1.3 0.012 14.3 0.9 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel RR_TM4-6 PF06459.7 ETO10768.1 - 0.019 14.8 2.7 0.022 14.6 1.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MRVI1 PF05781.7 ETO10768.1 - 0.037 12.4 0.0 0.045 12.1 0.0 1.0 1 0 0 1 1 1 0 MRVI1 protein OATP PF03137.15 ETO10768.1 - 0.075 11.0 0.4 0.087 10.8 0.3 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Vfa1 PF08432.5 ETO10768.1 - 0.1 12.5 8.7 0.13 12.2 6.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 A_deaminase_N PF08451.6 ETO10768.1 - 0.19 11.7 1.6 0.26 11.3 1.1 1.1 1 0 0 1 1 1 0 Adenosine/AMP deaminase N-terminal EIIBC-GUT_N PF03612.9 ETO10768.1 - 0.22 11.1 1.1 0.25 10.9 0.8 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Med17 PF10156.4 ETO10768.1 - 0.35 9.0 3.7 0.37 9.0 2.5 1.0 1 0 0 1 1 1 0 Subunit 17 of Mediator complex FAM176 PF14851.1 ETO10768.1 - 0.7 9.5 2.8 0.82 9.3 2.0 1.1 1 0 0 1 1 1 0 FAM176 family SpoIIIAH PF12685.2 ETO10768.1 - 1.7 8.1 7.3 2 7.8 5.1 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein NPR3 PF03666.8 ETO10768.1 - 2.6 6.4 5.3 2.9 6.3 3.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.9 ETO10768.1 - 3.5 5.5 6.2 3.7 5.4 4.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Protocadherin PF08374.6 ETO10768.1 - 9.1 5.8 7.7 12 5.4 5.3 1.1 1 0 0 1 1 1 0 Protocadherin Ribosomal_S19 PF00203.16 ETO10770.1 - 0.0098 15.4 0.1 0.013 15.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 BLVR PF06375.6 ETO10770.1 - 3.3 7.5 6.2 4.8 6.9 4.3 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Exo_endo_phos_2 PF14529.1 ETO10771.1 - 1.9e-11 43.6 0.2 5.5e-11 42.1 0.2 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.18 ETO10771.1 - 0.0034 17.2 2.0 0.0034 17.2 1.4 2.5 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.1 ETO10771.1 - 2.3 7.9 10.8 7.7 6.2 2.0 2.9 2 0 0 2 2 2 0 Zinc knuckle WD40 PF00400.27 ETO10772.1 - 3.3e-09 36.2 2.1 8.6e-09 34.9 0.1 2.4 3 0 0 3 3 3 1 WD domain, G-beta repeat CdCA1 PF10563.4 ETO10772.1 - 0.045 13.2 1.5 0.38 10.2 0.0 2.1 2 0 0 2 2 2 0 Cadmium carbonic anhydrase repeat Kelch_1 PF01344.20 ETO10773.1 - 2.6e-08 33.2 6.2 4.4e-06 26.1 0.5 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.10 ETO10773.1 - 3.6e-06 26.5 1.1 0.00038 20.1 0.2 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.1 ETO10773.1 - 0.0001 21.9 0.1 0.0066 16.1 0.0 2.3 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO10773.1 - 0.00022 21.2 1.5 0.03 14.4 0.2 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.1 ETO10773.1 - 0.0023 17.8 4.0 0.13 12.2 0.7 2.5 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 ETO10773.1 - 0.016 15.3 0.1 0.82 9.9 0.0 2.4 2 0 0 2 2 2 0 Galactose oxidase, central domain TraC_F_IV PF11130.3 ETO10773.1 - 0.018 14.4 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer APG5 PF04106.7 ETO10774.1 - 0.25 10.8 3.5 0.51 9.7 1.3 1.8 1 1 1 2 2 2 0 Autophagy protein Apg5 PUF PF00806.14 ETO10775.1 - 1.8e-28 96.3 4.4 7.1e-06 25.2 0.0 7.4 7 0 0 7 7 7 5 Pumilio-family RNA binding repeat DUF445 PF04286.7 ETO10775.1 - 0.48 9.8 3.9 4.4 6.7 3.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF445) CCDC144C PF14915.1 ETO10776.1 - 0.054 12.4 7.8 0.08 11.8 5.4 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region zf-SAP30 PF13866.1 ETO10776.1 - 1.3 8.7 13.4 0.15 11.7 4.3 2.6 1 1 1 2 2 2 0 SAP30 zinc-finger Peptidase_C14 PF00656.17 ETO10778.1 - 1.3e-10 41.4 0.4 2.6e-10 40.4 0.3 1.5 1 1 0 1 1 1 1 Caspase domain WD40 PF00400.27 ETO10779.1 - 5.1e-27 92.7 9.5 3.1e-11 42.6 0.3 5.0 5 1 0 5 5 5 3 WD domain, G-beta repeat Nuc_sug_transp PF04142.10 ETO10780.1 - 3.8e-14 52.3 9.6 5.3e-14 51.9 6.6 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 ETO10780.1 - 6.7e-07 29.0 19.3 0.00036 20.2 0.4 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 ETO10780.1 - 0.00088 19.3 23.8 0.0088 16.0 1.3 3.2 2 1 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 ETO10780.1 - 0.034 14.3 0.6 0.034 14.3 0.4 3.2 3 0 0 3 3 3 0 Multidrug resistance efflux transporter Ribosomal_L14 PF00238.14 ETO10781.1 - 1.7e-22 79.4 0.1 1.1e-21 76.8 0.1 1.8 1 1 0 1 1 1 1 Ribosomal protein L14p/L23e CDC45 PF02724.9 ETO10782.1 - 0.0055 14.8 1.7 0.0081 14.2 1.2 1.3 1 0 0 1 1 1 1 CDC45-like protein PigN PF04987.9 ETO10782.1 - 0.055 12.1 3.1 0.03 13.0 0.6 1.5 1 1 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) ABC2_membrane_3 PF12698.2 ETO10782.1 - 0.36 9.8 9.3 0.49 9.3 6.5 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein WD40 PF00400.27 ETO10785.1 - 9.5e-21 72.8 8.9 2.1e-10 40.0 0.0 3.3 3 1 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO10785.1 - 3.1e-05 22.3 1.4 0.00021 19.5 0.7 2.2 1 1 1 2 2 2 1 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO10785.1 - 0.1 11.8 4.7 0.44 9.8 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4221) DUF3355 PF11835.3 ETO10786.1 - 0.14 11.9 0.1 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3355) Pkinase PF00069.20 ETO10787.1 - 2.2e-38 131.9 0.1 4.1e-38 131.0 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO10787.1 - 2.1e-18 66.3 0.0 1.9e-16 59.8 0.0 2.6 3 0 0 3 3 3 1 Protein tyrosine kinase Kdo PF06293.9 ETO10787.1 - 0.00061 18.9 0.0 0.0012 17.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETO10787.1 - 0.0074 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETO10787.1 - 0.16 11.6 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Mannosyl_trans3 PF11051.3 ETO10788.1 - 3.1e-05 23.4 0.1 4.3e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.11 ETO10788.1 - 0.12 12.1 0.3 0.21 11.3 0.1 1.4 1 1 0 1 1 1 0 Nucleotide-diphospho-sugar transferase TMEMspv1-c74-12 PF11044.3 ETO10789.1 - 0.051 13.1 0.5 0.12 11.9 0.4 1.6 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF2824 PF11039.3 ETO10789.1 - 0.086 12.5 0.3 0.11 12.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2824) BP28CT PF08146.7 ETO10789.1 - 0.11 12.1 5.3 0.049 13.3 2.2 1.4 1 1 0 1 1 1 0 BP28CT (NUC211) domain WD40 PF00400.27 ETO10793.1 - 4.8e-59 194.2 14.6 1.3e-11 43.8 0.8 5.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO10793.1 - 3.2e-08 32.1 4.5 0.059 11.5 0.0 5.0 2 1 3 5 5 5 5 Nucleoporin Nup120/160 Fes1 PF08609.5 ETO10794.1 - 0.5 10.8 3.4 2.6 8.6 2.3 2.1 1 1 0 1 1 1 0 Nucleotide exchange factor Fes1 BAF1_ABF1 PF04684.8 ETO10794.1 - 1.9 7.2 10.3 2.9 6.6 7.1 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF912 PF06024.7 ETO10794.1 - 3.8 7.6 5.9 8.2 6.5 0.5 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4175 PF13779.1 ETO10794.1 - 4.2 4.9 13.6 5.3 4.6 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Exo_endo_phos PF03372.18 ETO10795.1 - 7.8e-15 55.4 0.0 1.5e-14 54.5 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 ETO10795.1 - 8.5e-05 22.1 0.0 0.0002 20.9 0.0 1.7 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase MRL1 PF13003.2 ETO10795.1 - 0.14 11.9 5.6 0.039 13.7 1.1 2.2 2 0 0 2 2 2 0 Ribosomal protein L1 SBF2 PF12335.3 ETO10796.1 - 8.5e-05 21.9 0.9 8.5e-05 21.9 0.6 2.0 2 0 0 2 2 2 1 Myotubularin protein DUF3744 PF12558.3 ETO10797.1 - 0.68 10.4 5.4 3.2 8.2 0.5 3.0 2 1 1 3 3 3 0 ATP-binding cassette cobalt transporter WD40 PF00400.27 ETO10798.1 - 1.8e-43 144.8 10.8 4.5e-11 42.1 0.1 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO10798.1 - 8.1e-10 37.4 2.9 0.0017 16.5 0.5 3.6 1 1 2 3 3 3 3 Nucleoporin Nup120/160 DUF851 PF05867.6 ETO10798.1 - 0.016 14.4 0.1 0.074 12.2 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF851) WD40 PF00400.27 ETO10799.1 - 5.3e-48 159.2 18.7 1e-09 37.8 0.1 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat DUF1652 PF07865.6 ETO10799.1 - 1.9e-05 24.1 0.3 0.064 12.8 0.0 4.1 5 1 0 5 5 5 2 Protein of unknown function (DUF1652) Nucleoporin_N PF08801.6 ETO10799.1 - 0.0036 16.0 7.7 0.23 10.1 0.1 4.0 1 1 2 4 4 4 2 Nup133 N terminal like Nup160 PF11715.3 ETO10799.1 - 0.015 13.4 7.4 1.1 7.2 0.0 4.0 4 2 1 5 5 5 0 Nucleoporin Nup120/160 PD40 PF07676.7 ETO10799.1 - 0.018 14.7 0.6 27 4.5 0.1 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 ETO10801.1 - 5.9e-26 89.3 11.4 3.7e-10 39.3 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO10801.1 - 8.9e-10 37.3 2.4 4e-05 21.9 0.2 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO10801.1 - 0.0072 15.1 3.7 0.098 11.3 0.8 2.6 1 1 2 3 3 3 1 Nup133 N terminal like DUF4221 PF13970.1 ETO10801.1 - 0.55 9.4 7.9 0.14 11.4 0.2 2.8 2 1 2 4 4 4 0 Domain of unknown function (DUF4221) ABC2_membrane PF01061.19 ETO10802.1 - 8.6e-26 90.4 10.9 1e-25 90.1 7.6 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 ETO10802.1 - 2e-07 30.4 6.8 2.1e-07 30.2 4.7 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.2 ETO10802.1 - 0.0041 16.0 1.7 0.0045 15.8 1.2 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein SNAP PF14938.1 ETO10803.1 - 1.6e-36 125.9 3.7 2.1e-36 125.5 2.6 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_2 PF07719.12 ETO10803.1 - 1.4e-06 27.7 6.1 0.0085 15.9 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO10803.1 - 7.3e-05 22.3 6.1 0.035 13.7 0.2 3.3 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 ETO10803.1 - 0.00012 21.4 8.9 0.11 12.1 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO10803.1 - 0.00015 21.2 7.1 0.0047 16.6 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO10803.1 - 0.00017 21.1 10.7 0.1 12.4 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO10803.1 - 0.0013 18.8 1.5 0.011 15.8 0.3 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 ETO10803.1 - 0.0013 18.5 3.1 0.027 14.3 1.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO10803.1 - 0.0034 17.9 2.4 0.062 13.9 0.2 2.7 3 0 0 3 3 2 1 Tetratricopeptide repeat Clathrin PF00637.15 ETO10803.1 - 0.0091 15.6 2.1 0.029 13.9 0.7 2.1 2 0 0 2 2 2 1 Region in Clathrin and VPS TPR_14 PF13428.1 ETO10803.1 - 0.049 14.2 0.3 23 5.9 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat Mt_ATP-synt_B PF05405.9 ETO10803.1 - 0.12 11.8 0.0 0.31 10.4 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) MIT PF04212.13 ETO10803.1 - 0.12 12.2 3.6 12 5.8 0.1 3.3 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain MerR-DNA-bind PF09278.6 ETO10803.1 - 0.16 12.3 0.4 0.36 11.2 0.3 1.6 1 0 0 1 1 1 0 MerR, DNA binding TPR_6 PF13174.1 ETO10803.1 - 0.86 10.1 4.2 33 5.2 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat NSF PF02071.15 ETO10803.1 - 2.2 9.1 6.1 79 4.5 0.2 3.9 3 2 1 4 4 4 0 Aromatic-di-Alanine (AdAR) repeat TPR_10 PF13374.1 ETO10803.1 - 4.6 7.2 5.7 1.6 8.7 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.7 ETO10803.1 - 6.9 6.5 9.4 2 8.2 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1777 PF08648.7 ETO10804.1 - 8.8 6.0 55.8 1.2 8.8 21.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1777) WD40 PF00400.27 ETO10805.1 - 1.4e-07 31.0 13.5 5.3e-05 22.9 0.5 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat NlpE PF04170.7 ETO10806.1 - 0.054 13.8 0.3 0.093 13.1 0.1 1.5 1 1 0 1 1 1 0 NlpE N-terminal domain ERp29 PF07749.7 ETO10806.1 - 0.11 13.1 3.1 0.18 12.4 2.1 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain WD40 PF00400.27 ETO10808.1 - 1.6e-63 208.4 18.1 1.2e-12 47.1 0.2 7.8 7 1 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO10808.1 - 3.7e-13 49.6 3.2 1.2e-08 34.9 0.4 3.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Kelch_6 PF13964.1 ETO10808.1 - 1.3e-09 37.7 8.4 0.0014 18.7 0.0 5.9 6 0 0 6 6 6 2 Kelch motif Cytochrom_D1 PF02239.11 ETO10808.1 - 1.1e-05 23.9 1.9 0.14 10.3 0.0 3.7 1 1 3 4 4 4 2 Cytochrome D1 heme domain DPPIV_N PF00930.16 ETO10808.1 - 0.0001 21.0 0.1 0.38 9.2 0.0 2.7 1 1 0 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Kelch_4 PF13418.1 ETO10808.1 - 0.00028 20.5 1.7 2.1 8.1 0.0 4.5 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO10808.1 - 0.00053 20.0 0.4 0.037 14.1 0.0 3.8 4 0 0 4 4 4 1 Galactose oxidase, central domain Ricin_B_lectin PF00652.17 ETO10808.1 - 0.0006 19.8 1.9 0.0044 17.0 0.1 2.6 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Kelch_1 PF01344.20 ETO10808.1 - 0.0029 17.1 10.8 0.19 11.2 0.0 4.5 4 0 0 4 4 4 1 Kelch motif N_Asn_amidohyd PF14736.1 ETO10808.1 - 0.0066 15.3 0.1 0.98 8.2 0.0 2.3 2 0 0 2 2 2 1 Protein N-terminal asparagine amidohydrolase PD40 PF07676.7 ETO10808.1 - 0.058 13.0 4.6 25 4.6 0.0 5.0 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Gmad1 PF10647.4 ETO10808.1 - 0.066 12.6 0.0 0.32 10.3 0.0 2.0 3 0 0 3 3 3 0 Lipoprotein LpqB beta-propeller domain Kelch_2 PF07646.10 ETO10808.1 - 0.1 12.4 3.0 16 5.4 0.0 4.2 4 0 0 4 4 4 0 Kelch motif Kelch_5 PF13854.1 ETO10808.1 - 2.9 7.9 5.2 70 3.5 0.2 4.2 5 0 0 5 5 5 0 Kelch motif PRA-PH PF01503.12 ETO10809.1 - 0.019 15.2 0.7 0.038 14.2 0.5 1.5 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase FlgN PF05130.7 ETO10809.1 - 0.024 14.8 11.6 0.027 14.6 8.1 1.0 1 0 0 1 1 1 0 FlgN protein Hexokinase_2 PF03727.11 ETO10809.1 - 0.035 13.3 1.4 0.038 13.1 1.0 1.1 1 0 0 1 1 1 0 Hexokinase Phage_GP20 PF06810.6 ETO10809.1 - 0.065 12.6 15.5 0.14 11.6 10.8 1.6 1 1 0 1 1 1 0 Phage minor structural protein GP20 Use1 PF09753.4 ETO10809.1 - 0.11 11.9 9.8 0.23 10.8 0.3 2.1 1 1 1 2 2 2 0 Membrane fusion protein Use1 SLA_LP_auto_ag PF05889.8 ETO10809.1 - 0.12 10.8 3.7 0.12 10.7 2.5 1.1 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) FlxA PF14282.1 ETO10809.1 - 0.13 12.1 10.6 0.15 11.9 6.8 1.5 1 1 0 1 1 1 0 FlxA-like protein PhageMin_Tail PF10145.4 ETO10809.1 - 0.16 11.5 2.3 0.18 11.4 1.6 1.2 1 0 0 1 1 1 0 Phage-related minor tail protein APG6 PF04111.7 ETO10809.1 - 0.31 10.0 16.6 0.32 10.0 11.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4618 PF15397.1 ETO10809.1 - 0.32 10.3 13.1 0.41 9.9 9.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) HemX PF04375.9 ETO10809.1 - 0.36 9.3 6.4 0.42 9.1 4.4 1.3 1 1 0 1 1 1 0 HemX Cortex-I_coil PF09304.5 ETO10809.1 - 0.37 10.8 14.3 0.67 10.0 9.8 1.5 1 1 0 1 1 1 0 Cortexillin I, coiled coil Fib_alpha PF08702.5 ETO10809.1 - 0.38 10.8 8.3 0.41 10.7 5.8 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family GAS PF13851.1 ETO10809.1 - 0.42 9.7 18.7 0.96 8.6 13.0 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Phage_min_cap2 PF06152.6 ETO10809.1 - 0.47 9.3 8.0 0.54 9.1 5.6 1.1 1 0 0 1 1 1 0 Phage minor capsid protein 2 HALZ PF02183.13 ETO10809.1 - 0.53 10.0 12.7 1.2 8.8 3.1 3.2 2 1 0 2 2 2 0 Homeobox associated leucine zipper Het-C PF07217.6 ETO10809.1 - 0.54 8.3 4.0 0.56 8.3 2.8 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C RmuC PF02646.11 ETO10809.1 - 0.55 9.0 8.8 0.65 8.7 6.1 1.1 1 0 0 1 1 1 0 RmuC family DUF2968 PF11180.3 ETO10809.1 - 0.59 9.4 7.4 0.66 9.3 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) NYD-SP28_assoc PF14775.1 ETO10809.1 - 0.61 9.8 6.0 1.2 8.8 0.9 2.5 1 1 1 2 2 2 0 Sperm tail C-terminal domain Ran-binding PF05508.6 ETO10809.1 - 0.61 8.9 5.7 0.71 8.7 3.9 1.1 1 0 0 1 1 1 0 RanGTP-binding protein OmpH PF03938.9 ETO10809.1 - 0.67 9.8 14.4 0.75 9.7 10.0 1.0 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CorA PF01544.13 ETO10809.1 - 0.68 8.9 2.9 0.66 8.9 2.0 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein CALCOCO1 PF07888.6 ETO10809.1 - 0.74 8.0 15.6 0.84 7.8 10.8 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like YvrJ PF12841.2 ETO10809.1 - 0.9 8.8 5.8 0.89 8.9 0.9 2.5 3 0 0 3 3 2 0 YvrJ protein family H-kinase_dim PF02895.9 ETO10809.1 - 0.91 9.9 4.5 32 4.9 3.1 2.2 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain Kinesin-relat_1 PF12711.2 ETO10809.1 - 1.1 9.6 14.9 4.1 7.8 6.2 2.1 1 1 1 2 2 2 0 Kinesin motor GLE1 PF07817.8 ETO10809.1 - 1.2 8.0 6.7 1.4 7.8 3.8 1.5 1 1 1 2 2 2 0 GLE1-like protein TMPIT PF07851.8 ETO10809.1 - 1.2 8.1 12.0 1.3 7.9 8.3 1.0 1 0 0 1 1 1 0 TMPIT-like protein Syntaxin_2 PF14523.1 ETO10809.1 - 1.2 9.1 8.9 2.3 8.3 6.2 1.5 1 1 0 1 1 1 0 Syntaxin-like protein Silic_transp PF03842.8 ETO10809.1 - 1.3 6.9 3.2 1.3 6.9 1.9 1.2 1 1 0 1 1 1 0 Silicon transporter DUF16 PF01519.11 ETO10809.1 - 1.3 9.2 13.9 4.5 7.5 9.6 1.8 1 1 0 1 1 1 0 Protein of unknown function DUF16 HSCB_C PF07743.8 ETO10809.1 - 1.4 9.4 12.3 1.6 9.2 2.5 2.1 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain DUF3450 PF11932.3 ETO10809.1 - 1.4 8.0 8.8 1.7 7.8 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) LRS4 PF10422.4 ETO10809.1 - 1.5 8.1 12.7 1.7 7.9 8.8 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 zf-C4H2 PF10146.4 ETO10809.1 - 1.6 8.7 15.0 1.7 8.6 10.4 1.0 1 0 0 1 1 1 0 Zinc finger-containing protein DUF4200 PF13863.1 ETO10809.1 - 1.7 8.5 20.7 2.1 8.3 14.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF972 PF06156.8 ETO10809.1 - 1.8 8.9 14.6 1.5 9.2 4.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) ERM PF00769.14 ETO10809.1 - 1.8 8.0 18.4 2.1 7.8 12.8 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Latarcin PF10279.4 ETO10809.1 - 2.5 8.3 9.2 57 3.9 6.4 2.6 1 1 0 1 1 1 0 Latarcin precursor Atg14 PF10186.4 ETO10809.1 - 2.8 6.8 12.5 3.2 6.6 8.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 XLF PF09302.6 ETO10809.1 - 3.3 7.4 10.2 3.4 7.4 1.3 2.4 1 1 0 2 2 2 0 XLF (XRCC4-like factor) zf-DNA_Pol PF08996.5 ETO10809.1 - 3.6 6.8 8.0 2.3 7.5 2.0 1.9 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger IncA PF04156.9 ETO10809.1 - 4.1 6.9 14.3 5.2 6.6 9.9 1.3 1 0 0 1 1 1 0 IncA protein zf-CpG_bind_C PF12269.3 ETO10809.1 - 4.2 6.7 7.8 4.8 6.5 5.0 1.4 1 1 0 1 1 1 0 CpG binding protein zinc finger C terminal domain DUF342 PF03961.8 ETO10809.1 - 4.2 5.6 14.2 4.3 5.6 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Med9 PF07544.8 ETO10809.1 - 4.5 7.0 10.2 6 6.6 7.0 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF2458 PF10454.4 ETO10809.1 - 4.7 7.1 12.7 8.8 6.2 8.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2458) DivIC PF04977.10 ETO10809.1 - 5.3 6.6 15.8 0.58 9.6 3.3 2.8 1 1 2 3 3 3 0 Septum formation initiator Tox-GHH PF15636.1 ETO10809.1 - 5.9 6.6 7.5 3.2 7.4 2.8 2.1 1 1 1 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin DUF948 PF06103.6 ETO10809.1 - 5.9 6.8 5.7 41 4.1 3.9 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Seryl_tRNA_N PF02403.17 ETO10809.1 - 6.2 6.8 16.1 19 5.3 11.1 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain HMG_box_2 PF09011.5 ETO10809.1 - 6.6 7.1 8.0 11 6.4 5.5 1.6 1 1 0 1 1 1 0 HMG-box domain DUF1664 PF07889.7 ETO10809.1 - 7.4 6.3 7.9 9.2 6.0 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4559 PF15112.1 ETO10809.1 - 7.6 5.6 13.4 8 5.5 9.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Glutaredoxin2_C PF04399.8 ETO10809.1 - 8.3 5.9 7.6 9.6 5.7 2.7 2.0 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain VSG_B PF13206.1 ETO10809.1 - 8.8 5.3 9.5 9.4 5.2 6.6 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain DUF919 PF06034.6 ETO10809.1 - 9.1 5.9 12.4 2.2 7.9 3.5 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DUF2570 PF10828.3 ETO10809.1 - 9.4 5.8 9.5 11 5.6 6.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) AAA_13 PF13166.1 ETO10809.1 - 9.9 4.4 14.2 10 4.4 9.8 1.0 1 0 0 1 1 1 0 AAA domain AMP-binding PF00501.23 ETO10811.1 - 1.5e-21 76.2 0.0 1.7e-21 76.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme UPF0118 PF01594.11 ETO10813.1 - 0.03 13.3 2.1 0.031 13.2 1.0 1.3 1 1 0 1 1 1 0 Domain of unknown function DUF20 DUF4376 PF14301.1 ETO10815.1 - 0.22 11.6 3.5 0.33 11.0 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4376) Red1 PF07964.6 ETO10815.1 - 0.74 7.8 8.9 1.1 7.3 6.2 1.2 1 0 0 1 1 1 0 Rec10 / Red1 WD40 PF00400.27 ETO10818.1 - 3.5e-64 210.5 15.6 1.3e-13 50.1 0.3 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO10818.1 - 2.8e-11 42.3 0.5 0.00087 17.6 0.0 3.3 2 1 0 3 3 3 3 Cytochrome D1 heme domain Nup160 PF11715.3 ETO10818.1 - 1.6e-05 23.2 6.3 0.0056 14.8 0.5 3.7 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO10818.1 - 1.7e-05 24.4 0.4 4.6e-05 22.9 0.3 1.8 1 1 0 1 1 1 1 PQQ-like domain Str_synth PF03088.11 ETO10818.1 - 0.00018 21.5 0.2 0.25 11.4 0.0 4.1 4 2 1 5 5 5 1 Strictosidine synthase Me-amine-dh_H PF06433.6 ETO10818.1 - 0.0055 15.3 0.0 0.11 11.0 0.0 2.5 2 1 2 4 4 4 1 Methylamine dehydrogenase heavy chain (MADH) Nucleoporin_N PF08801.6 ETO10818.1 - 0.0062 15.3 10.8 3.4 6.3 0.0 5.0 1 1 4 5 5 5 2 Nup133 N terminal like PD40 PF07676.7 ETO10818.1 - 0.016 14.8 2.9 18 5.1 0.0 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 ETO10818.1 - 0.031 13.3 1.2 0.67 8.9 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1258) Ubiquitin_3 PF14836.1 ETO10818.1 - 0.045 13.4 0.1 0.81 9.3 0.0 2.7 3 0 0 3 3 3 0 Ubiquitin-like domain RVT_thumb PF06817.9 ETO10818.1 - 0.046 13.2 0.1 9.5 5.8 0.0 2.7 2 0 0 2 2 2 0 Reverse transcriptase thumb domain SPX PF03105.14 ETO10819.1 - 0.0092 15.7 6.2 0.015 15.0 4.3 1.4 1 0 0 1 1 1 1 SPX domain DUF4613 PF15390.1 ETO10819.1 - 0.3 9.2 9.5 0.52 8.4 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4613) RCC1 PF00415.13 ETO10820.1 - 2.7e-07 30.7 0.5 0.00037 20.6 0.0 3.3 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO10820.1 - 7.9e-05 22.1 10.2 0.067 12.8 0.3 3.5 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat Acetyltransf_1 PF00583.19 ETO10821.1 - 2e-15 56.6 0.0 2.6e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETO10821.1 - 3.5e-09 36.6 0.1 5e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETO10821.1 - 7.6e-08 32.0 0.0 1.1e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 ETO10821.1 - 6e-06 26.2 0.1 7.4e-06 25.9 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETO10821.1 - 1.1e-05 25.2 0.0 1.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETO10821.1 - 1.5e-05 25.0 0.0 2.1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 ETO10821.1 - 0.02 14.7 0.0 0.024 14.5 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Docking PF08990.6 ETO10821.1 - 0.022 13.9 0.1 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 Erythronolide synthase docking Acetyltransf_3 PF13302.1 ETO10821.1 - 0.11 12.6 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DEAD PF00270.24 ETO10822.1 - 6e-31 107.2 0.9 1.1e-28 99.8 0.0 2.6 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 ETO10822.1 - 7.3e-12 44.9 0.1 2.2e-11 43.4 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.1 ETO10822.1 - 1e-05 24.7 0.4 3.1e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.10 ETO10822.1 - 0.007 16.2 0.3 0.032 14.0 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit NIF PF03031.13 ETO10822.1 - 0.014 15.1 0.7 0.022 14.4 0.5 1.4 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase DNA_mis_repair PF01119.14 ETO10823.1 - 4.2e-21 74.5 1.9 1.4e-20 72.8 1.3 1.8 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain RCC1_2 PF13540.1 ETO10824.1 - 2.7e-07 30.0 0.2 6e-05 22.5 0.0 2.6 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 ETO10824.1 - 0.054 13.7 0.3 60 3.9 0.0 3.3 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat HEAT_2 PF13646.1 ETO10825.1 - 2.9e-14 53.0 0.0 1.6e-05 25.0 0.0 6.2 3 2 5 8 8 8 5 HEAT repeats HEAT PF02985.17 ETO10825.1 - 2.6e-13 48.8 0.9 0.029 14.4 0.0 6.7 8 0 0 8 8 6 3 HEAT repeat NACHT PF05729.7 ETO10825.1 - 6.6e-11 42.1 0.0 3.5e-10 39.7 0.0 2.3 1 0 0 1 1 1 1 NACHT domain Ank_5 PF13857.1 ETO10825.1 - 1.1e-05 25.5 0.1 4.2e-05 23.6 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 ETO10825.1 - 1.6e-05 24.4 0.0 8e-05 22.2 0.0 2.3 1 0 0 1 1 1 1 Ankyrin repeat HEAT_EZ PF13513.1 ETO10825.1 - 2.5e-05 24.6 0.0 14 6.3 0.0 5.8 6 0 0 6 6 5 0 HEAT-like repeat Ank_4 PF13637.1 ETO10825.1 - 3.1e-05 24.3 0.4 0.00029 21.2 0.0 2.9 3 0 0 3 3 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO10825.1 - 6.6e-05 22.7 0.2 0.00063 19.7 0.0 2.9 2 0 0 2 2 1 1 Ankyrin repeat Ank_2 PF12796.2 ETO10825.1 - 0.0011 19.3 0.0 0.0058 16.9 0.0 2.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Vac14_Fab1_bd PF12755.2 ETO10825.1 - 0.0025 18.1 14.5 0.051 13.9 0.6 5.7 4 1 2 6 6 4 3 Vacuolar 14 Fab1-binding region AAA_18 PF13238.1 ETO10825.1 - 0.005 17.1 0.1 0.005 17.1 0.0 3.4 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.1 ETO10825.1 - 0.0077 16.3 0.0 0.064 13.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETO10825.1 - 0.011 15.6 0.0 0.075 13.0 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.16 ETO10825.1 - 0.043 12.9 0.0 0.14 11.3 0.0 1.8 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI WD40 PF00400.27 ETO10826.1 - 1.6e-50 167.2 25.3 5.4e-10 38.7 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO10826.1 - 1.7e-08 33.0 3.2 0.21 9.7 0.0 4.6 1 1 3 5 5 5 4 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO10826.1 - 0.018 14.7 1.5 0.19 11.5 0.1 3.0 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Ig_2 PF13895.1 ETO10826.1 - 0.038 14.1 0.3 0.086 12.9 0.2 1.5 1 0 0 1 1 1 0 Immunoglobulin domain BBS2_N PF14781.1 ETO10826.1 - 0.15 11.7 3.4 1.9 8.1 0.1 2.8 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal WD40 PF00400.27 ETO10827.1 - 7.7e-181 580.3 45.6 1.6e-13 49.9 0.0 16.4 15 1 1 16 16 16 14 WD domain, G-beta repeat PQQ_2 PF13360.1 ETO10827.1 - 5.5e-18 65.3 10.2 0.002 17.6 0.2 6.6 2 2 5 7 7 7 7 PQQ-like domain DUF1258 PF06869.7 ETO10827.1 - 9.2e-10 38.0 1.5 0.38 9.8 0.0 7.6 4 2 5 9 9 9 2 Protein of unknown function (DUF1258) Cytochrom_D1 PF02239.11 ETO10827.1 - 1.2e-07 30.4 8.4 0.0029 15.9 0.2 5.6 5 1 0 6 6 6 3 Cytochrome D1 heme domain Gmad1 PF10647.4 ETO10827.1 - 4.4e-07 29.5 6.8 0.64 9.3 0.1 7.2 3 2 3 7 7 7 3 Lipoprotein LpqB beta-propeller domain NACHT PF05729.7 ETO10827.1 - 3.9e-06 26.6 0.0 9.3e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO10827.1 - 0.00056 20.2 0.7 0.0053 17.0 0.1 3.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETO10827.1 - 0.0028 17.7 0.0 0.011 15.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain PD40 PF07676.7 ETO10827.1 - 0.005 16.4 27.5 32 4.3 0.0 12.2 14 0 0 14 14 14 0 WD40-like Beta Propeller Repeat PQQ PF01011.16 ETO10827.1 - 0.0091 15.4 0.0 1.8 8.2 0.0 4.8 7 0 0 7 7 7 1 PQQ enzyme repeat Kelch_6 PF13964.1 ETO10828.1 - 0.0025 17.8 0.1 0.12 12.5 0.0 2.9 3 0 0 3 3 3 1 Kelch motif AAA_18 PF13238.1 ETO10828.1 - 0.013 15.7 0.2 0.02 15.2 0.1 1.2 1 0 0 1 1 1 0 AAA domain CCSMST1 PF15013.1 ETO10829.1 - 0.07 13.0 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 CCSMST1 family CAP_GLY PF01302.20 ETO10831.1 - 0.0025 17.5 0.0 0.0047 16.5 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain WD40 PF00400.27 ETO10832.1 - 2e-32 109.8 3.4 1.4e-11 43.7 0.2 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO10832.1 - 0.00064 17.9 0.1 0.051 11.7 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 SUD-M PF11633.3 ETO10832.1 - 0.36 10.1 2.0 5.4 6.2 0.1 2.2 1 1 1 2 2 2 0 Single-stranded poly(A) binding domain PRKCSH_1 PF13015.1 ETO10834.1 - 3.3e-10 39.6 3.4 5.3e-10 38.9 2.0 1.7 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 ETO10834.1 - 0.0033 18.1 6.6 0.0033 18.1 4.6 3.5 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein LRV_FeS PF05484.6 ETO10834.1 - 0.044 13.3 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 LRV protein FeS4 cluster Peptidase_S49_N PF08496.5 ETO10834.1 - 0.15 11.8 0.5 0.25 11.1 0.3 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ribosomal_L29 PF00831.18 ETO10835.1 - 1.2e-17 63.3 6.2 1.2e-17 63.3 4.3 2.5 3 0 0 3 3 3 1 Ribosomal L29 protein 2OG-FeII_Oxy_4 PF13661.1 ETO10836.1 - 0.042 13.4 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily LVIVD PF08309.6 ETO10836.1 - 0.075 12.0 0.4 0.18 10.8 0.3 1.7 1 1 0 1 1 1 0 LVIVD repeat Joubert PF15392.1 ETO10837.1 - 0.0032 16.7 0.5 0.0058 15.9 0.3 1.5 1 0 0 1 1 1 1 Joubert syndrome-associated RGS PF00615.14 ETO10837.1 - 0.0033 17.5 1.4 0.0079 16.2 1.0 1.8 1 1 0 1 1 1 1 Regulator of G protein signaling domain V_ATPase_I PF01496.14 ETO10838.1 - 0.041 11.7 1.2 0.052 11.4 0.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1240 PF06836.7 ETO10838.1 - 0.092 12.9 1.7 0.17 12.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) Phosphoesterase PF04185.9 ETO10839.1 - 5e-38 131.2 0.7 4.6e-37 128.1 0.5 1.9 1 1 0 1 1 1 1 Phosphoesterase family Sulfatase PF00884.18 ETO10839.1 - 0.093 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Sulfatase WD40 PF00400.27 ETO10840.1 - 7.2e-42 139.8 4.0 3e-12 45.9 0.1 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 ETO10840.1 - 6e-09 35.8 1.2 0.0028 17.4 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO10840.1 - 3e-06 26.7 1.6 0.15 11.7 0.0 3.7 3 0 0 3 3 3 3 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO10840.1 - 3.3e-06 25.5 0.8 0.21 9.7 0.0 3.2 1 1 0 3 3 3 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO10840.1 - 0.0033 17.1 1.8 0.21 11.3 0.1 3.3 1 1 3 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Tcp10_C PF07202.8 ETO10840.1 - 0.048 13.2 0.1 1.5 8.3 0.0 2.5 1 1 1 2 2 2 0 T-complex protein 10 C-terminus Proteasome_A_N PF10584.4 ETO10840.1 - 1.4 8.3 4.8 21 4.5 0.0 3.4 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Rpp20 PF12328.3 ETO10841.1 - 0.01 15.4 1.1 0.015 14.9 0.8 1.2 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P COX16 PF14138.1 ETO10841.1 - 0.18 11.9 0.2 0.18 11.9 0.1 1.9 3 0 0 3 3 3 0 Cytochrome c oxidase assembly protein COX16 A_deaminase PF00962.17 ETO10842.1 - 0.02 13.8 0.3 0.025 13.4 0.2 1.1 1 0 0 1 1 1 0 Adenosine/AMP deaminase DUF4162 PF13732.1 ETO10842.1 - 0.17 12.4 2.6 0.39 11.2 1.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4162) ABC_tran PF00005.22 ETO10843.1 - 2e-17 63.8 0.1 7.3e-17 61.9 0.0 1.8 2 1 1 3 3 3 1 ABC transporter AAA_23 PF13476.1 ETO10843.1 - 0.099 12.9 0.1 0.23 11.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.2 ETO10844.1 - 2.9e-25 89.0 28.8 2.9e-25 89.0 20.0 1.9 1 1 1 2 2 2 1 ABC-2 family transporter protein DUF4274 PF14096.1 ETO10844.1 - 0.097 12.4 0.1 0.42 10.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4274) Peptidase_C14 PF00656.17 ETO10845.1 - 0.16 11.6 2.2 0.48 10.0 0.1 2.4 2 1 0 2 2 2 0 Caspase domain WPP PF13943.1 ETO10845.1 - 0.63 10.2 3.3 1.5 9.0 0.4 2.4 2 0 0 2 2 2 0 WPP domain DUF2661 PF10860.3 ETO10845.1 - 3.7 7.7 9.2 3.7 7.7 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2661) WD40 PF00400.27 ETO10846.1 - 0.00043 20.0 2.0 0.00044 20.0 0.3 1.8 2 0 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO10846.1 - 0.0036 15.4 0.0 0.0036 15.4 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 VPS9 PF02204.13 ETO10846.1 - 0.56 10.2 5.2 4.6 7.3 1.1 2.5 2 1 0 2 2 2 0 Vacuolar sorting protein 9 (VPS9) domain Transposase_31 PF04754.7 ETO10849.1 - 0.12 11.6 4.5 0.21 10.9 0.6 2.0 1 1 1 2 2 2 0 Putative transposase, YhgA-like Ank_2 PF12796.2 ETO10850.1 - 3.1e-10 40.2 0.0 5.7e-10 39.4 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO10850.1 - 2.5e-08 33.3 0.0 2e-05 24.1 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 ETO10850.1 - 1.6e-07 31.6 0.0 4e-06 27.2 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO10850.1 - 4.9e-05 23.4 0.1 0.00096 19.3 0.0 2.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO10850.1 - 5.3e-05 23.0 0.0 0.082 13.1 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Pribosyltran PF00156.22 ETO10850.1 - 0.13 12.0 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain Folate_carrier PF01770.13 ETO10852.1 - 0.0063 15.0 2.7 0.007 14.9 1.9 1.0 1 0 0 1 1 1 1 Reduced folate carrier CPSF100_C PF13299.1 ETO10852.1 - 0.079 13.1 1.7 0.089 12.9 1.2 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal U79_P34 PF03064.11 ETO10852.1 - 0.12 11.8 4.7 0.16 11.4 3.2 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 APG6 PF04111.7 ETO10852.1 - 0.25 10.3 7.1 0.29 10.1 5.0 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 EFhand_Ca_insen PF08726.5 ETO10852.1 - 0.32 10.9 2.4 2.6 8.0 0.1 2.2 1 1 1 2 2 2 0 Ca2+ insensitive EF hand Peptidase_S49_N PF08496.5 ETO10852.1 - 1.7 8.3 4.9 2.5 7.8 3.4 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Folate_carrier PF01770.13 ETO10853.1 - 0.00059 18.4 1.3 0.00067 18.2 0.9 1.0 1 0 0 1 1 1 1 Reduced folate carrier CPSF100_C PF13299.1 ETO10853.1 - 0.11 12.7 1.1 0.12 12.5 0.8 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal U79_P34 PF03064.11 ETO10853.1 - 1 8.8 7.0 1.1 8.6 4.9 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Transposase_22 PF02994.9 ETO10854.1 - 0.0046 15.5 4.5 0.0052 15.3 3.1 1.0 1 0 0 1 1 1 1 L1 transposable element HdeA PF06411.6 ETO10854.1 - 1.3 9.0 3.4 2.1 8.3 2.4 1.4 1 0 0 1 1 1 0 HdeA/HdeB family Syntaxin-6_N PF09177.6 ETO10855.1 - 0.0033 17.8 0.8 0.068 13.5 0.4 2.7 2 2 0 2 2 2 1 Syntaxin 6, N-terminal Gly_radical PF01228.16 ETO10855.1 - 0.17 12.2 0.5 5.3 7.4 0.0 2.7 1 1 0 2 2 2 0 Glycine radical Xpo1 PF08389.7 ETO10856.1 - 0.0015 18.4 2.3 0.006 16.5 1.6 1.9 1 1 0 1 1 1 1 Exportin 1-like protein DUF445 PF04286.7 ETO10856.1 - 0.058 12.9 1.9 0.087 12.3 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) JAB PF01398.16 ETO10857.1 - 2.4e-11 43.3 0.0 5.9e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 ETO10857.1 - 7.5e-09 35.6 0.2 1.4e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function RVT_1 PF00078.22 ETO10858.1 - 1.1e-21 77.1 0.0 1.4e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) tRNA-synt_1c_C PF03950.13 ETO10859.1 - 0.00019 21.1 5.9 0.00025 20.7 4.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain PAP_RNA-bind PF04926.10 ETO10860.1 - 0.013 14.9 8.4 0.042 13.3 0.1 3.5 2 1 1 3 3 3 0 Poly(A) polymerase predicted RNA binding domain Nup35_RRM PF05172.8 ETO10861.1 - 0.077 12.7 0.2 0.14 11.9 0.1 1.4 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF3399 PF11879.3 ETO10862.1 - 0.043 14.0 0.1 0.087 13.0 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3399) FliJ PF02050.11 ETO10863.1 - 5.1e-05 23.3 13.4 0.00011 22.2 9.3 1.5 1 0 0 1 1 1 1 Flagellar FliJ protein IncA PF04156.9 ETO10863.1 - 0.0011 18.5 9.5 0.0011 18.5 6.6 1.8 2 0 0 2 2 1 1 IncA protein Filo_VP35 PF02097.10 ETO10863.1 - 0.005 16.0 1.8 0.0061 15.8 0.2 1.7 2 0 0 2 2 2 1 Filoviridae VP35 Fib_alpha PF08702.5 ETO10863.1 - 0.0085 16.2 11.8 0.0085 16.2 8.2 2.2 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family Myosin_tail_1 PF01576.14 ETO10863.1 - 0.01 13.6 11.4 0.015 13.1 7.9 1.1 1 0 0 1 1 1 0 Myosin tail SlyX PF04102.7 ETO10863.1 - 0.032 14.5 5.6 0.032 14.5 3.9 3.0 2 1 1 3 3 3 0 SlyX TMF_TATA_bd PF12325.3 ETO10863.1 - 0.051 13.2 9.9 0.17 11.6 6.8 1.9 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF91 PF01939.11 ETO10863.1 - 0.057 12.5 0.5 0.12 11.5 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF91 Cluap1 PF10234.4 ETO10863.1 - 0.058 12.5 7.2 0.099 11.8 5.0 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 FemAB PF02388.11 ETO10863.1 - 0.062 11.9 6.9 0.11 11.1 4.8 1.3 1 0 0 1 1 1 0 FemAB family Frigida PF07899.6 ETO10863.1 - 0.067 11.9 6.6 0.12 11.0 4.6 1.4 1 0 0 1 1 1 0 Frigida-like protein TMF_DNA_bd PF12329.3 ETO10863.1 - 0.083 12.7 13.0 0.067 13.0 7.0 2.2 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF641 PF04859.7 ETO10863.1 - 0.17 11.6 6.1 0.44 10.3 4.3 1.7 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF4446 PF14584.1 ETO10863.1 - 0.17 11.7 3.2 0.48 10.2 2.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) DUF3450 PF11932.3 ETO10863.1 - 0.23 10.6 11.9 0.36 10.0 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Laminin_II PF06009.7 ETO10863.1 - 0.28 10.9 10.2 0.8 9.4 7.0 1.7 1 0 0 1 1 1 0 Laminin Domain II M_domain PF12938.2 ETO10863.1 - 0.32 10.7 15.6 0.8 9.4 10.5 1.9 1 1 0 1 1 1 0 M domain of GW182 DUF4407 PF14362.1 ETO10863.1 - 0.33 9.8 7.1 0.51 9.2 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATG16 PF08614.6 ETO10863.1 - 0.39 10.5 17.6 1.3 8.8 12.2 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) V_ATPase_I PF01496.14 ETO10863.1 - 0.41 8.4 5.1 0.57 7.9 3.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HemX PF04375.9 ETO10863.1 - 1.2 7.7 11.2 1.8 7.1 7.8 1.2 1 0 0 1 1 1 0 HemX DUF2951 PF11166.3 ETO10863.1 - 1.4 8.8 8.0 1.1 9.1 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) YlbD_coat PF14071.1 ETO10863.1 - 1.7 8.7 12.0 0.27 11.3 5.4 1.8 2 0 0 2 2 1 0 Putative coat protein DUF4140 PF13600.1 ETO10863.1 - 5.9 7.4 8.3 0.68 10.4 2.0 2.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Bap31 PF05529.7 ETO10863.1 - 6.5 6.1 12.8 0.64 9.4 5.3 1.9 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like PLATZ PF04640.9 ETO10863.1 - 8.3 6.6 9.1 15 5.9 0.8 3.0 3 0 0 3 3 2 0 PLATZ transcription factor FlxA PF14282.1 ETO10863.1 - 8.4 6.3 25.8 2 8.4 6.8 2.8 1 1 1 2 2 2 0 FlxA-like protein Packaging_FI PF14000.1 ETO10864.1 - 0.037 14.2 1.1 0.037 14.2 0.8 3.8 3 1 1 4 4 4 0 DNA packaging protein FI Hexokinase_1 PF00349.16 ETO10865.1 - 0.1 11.8 0.1 0.21 10.8 0.0 1.6 2 0 0 2 2 2 0 Hexokinase DUF1392 PF07154.6 ETO10865.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1392) Epimerase PF01370.16 ETO10866.1 - 6.2e-06 25.8 0.0 7.8e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETO10866.1 - 0.059 13.3 0.0 0.077 13.0 0.0 1.1 1 0 0 1 1 1 0 NADH(P)-binding Ribosomal_L4 PF00573.17 ETO10867.1 - 6.2e-19 68.1 0.0 3.1e-18 65.8 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein L4/L1 family Cation_efflux PF01545.16 ETO10868.1 - 3.7e-29 101.6 1.6 5.8e-29 101.0 1.1 1.3 1 0 0 1 1 1 1 Cation efflux family Glyco_hydro_12 PF01670.11 ETO10869.1 - 3.7e-13 49.5 2.2 1.7e-12 47.4 0.5 2.0 1 1 1 2 2 2 1 Glycosyl hydrolase family 12 DUF846 PF05832.7 ETO10869.1 - 0.017 14.8 0.7 0.04 13.6 0.5 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) DUF3960 PF13142.1 ETO10869.1 - 0.1 12.3 0.1 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3960) CHAT PF12770.2 ETO10870.1 - 6.9e-05 22.1 0.0 7.7e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 CHAT domain UPF0180 PF03698.8 ETO10873.1 - 0.025 14.4 0.0 0.059 13.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) DUF4243 PF14027.1 ETO10873.1 - 0.16 11.4 1.1 0.34 10.3 0.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4243) MRL1 PF13003.2 ETO10873.1 - 5.9 6.7 14.8 2.5 7.9 4.6 2.4 1 1 1 2 2 2 0 Ribosomal protein L1 Pkinase_Tyr PF07714.12 ETO10875.1 - 3.3e-66 223.0 0.0 4.2e-66 222.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 ETO10875.1 - 1e-55 188.6 0.0 1.5e-55 188.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 ETO10875.1 - 0.00069 18.7 0.1 0.0014 17.7 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 ETO10875.1 - 0.054 12.8 0.0 0.097 11.9 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL HupF_HypC PF01455.13 ETO10875.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 HupF/HypC family DASH_Dam1 PF08653.5 ETO10876.1 - 0.082 12.6 1.7 0.81 9.4 0.4 2.6 2 0 0 2 2 2 0 DASH complex subunit Dam1 UME PF08064.8 ETO10876.1 - 0.15 12.0 0.2 0.15 12.0 0.1 1.6 2 0 0 2 2 2 0 UME (NUC010) domain DUF4220 PF13968.1 ETO10876.1 - 0.18 10.9 0.5 0.25 10.4 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DUF1336 PF07059.7 ETO10877.1 - 5.7e-26 91.3 0.0 2.8e-12 46.5 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1336) Taxilin PF09728.4 ETO10878.1 - 5e-05 22.5 5.9 5e-05 22.5 4.1 3.0 2 1 1 3 3 3 2 Myosin-like coiled-coil protein Cortex-I_coil PF09304.5 ETO10878.1 - 4.2 7.4 24.1 0.058 13.4 1.7 3.2 2 1 1 3 3 3 0 Cortexillin I, coiled coil Actin PF00022.14 ETO10880.1 - 4.5e-95 318.3 0.0 5.1e-95 318.1 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 ETO10880.1 - 0.00098 17.8 0.2 0.0014 17.2 0.1 1.1 1 0 0 1 1 1 1 MreB/Mbl protein DUF3972 PF13118.1 ETO10880.1 - 0.089 12.8 0.1 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) WD40 PF00400.27 ETO10883.1 - 7.2e-67 219.0 13.3 2.5e-13 49.3 0.1 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO10883.1 - 6.5e-11 42.3 0.1 1.1e-05 25.1 0.1 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO10883.1 - 8.6e-09 34.0 1.9 0.024 12.7 0.1 4.2 1 1 4 5 5 5 3 Nucleoporin Nup120/160 Nbas_N PF15492.1 ETO10883.1 - 3.7e-07 29.5 0.7 0.0066 15.5 0.0 3.8 1 1 3 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 ETO10883.1 - 3e-06 25.7 0.4 0.0028 16.0 0.0 2.9 1 1 2 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO10883.1 - 1.2e-05 24.2 2.4 2.7 6.6 0.0 4.5 1 1 3 4 4 4 2 Nup133 N terminal like PD40 PF07676.7 ETO10883.1 - 1.3e-05 24.6 5.5 1.4 8.6 0.0 5.0 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 ETO10883.1 - 1.5e-05 24.1 8.5 1.4 8.2 0.0 4.4 4 0 0 4 4 4 2 Proteasome subunit A N-terminal signature Coatomer_WDAD PF04053.9 ETO10883.1 - 2.6e-05 23.2 0.5 0.00082 18.2 0.2 2.2 1 1 1 2 2 2 1 Coatomer WD associated region PQQ_2 PF13360.1 ETO10883.1 - 8.6e-05 22.1 0.1 0.0016 17.9 0.1 2.7 1 1 0 1 1 1 1 PQQ-like domain Resistin PF06954.6 ETO10883.1 - 0.0007 19.8 0.1 13 6.1 0.0 3.8 2 1 2 4 4 4 0 Resistin Ricin_B_lectin PF00652.17 ETO10883.1 - 0.00071 19.6 1.1 0.12 12.4 0.6 3.2 1 1 2 3 3 3 1 Ricin-type beta-trefoil lectin domain Hira PF07569.6 ETO10883.1 - 0.0059 15.8 0.1 13 4.9 0.0 3.8 3 1 1 4 4 4 0 TUP1-like enhancer of split lci PF12197.3 ETO10883.1 - 0.011 15.3 1.2 3.4 7.3 0.0 2.9 3 0 0 3 3 3 0 Bacillus cereus group antimicrobial protein DPPIV_N PF00930.16 ETO10883.1 - 0.029 12.9 0.0 16 3.9 0.0 3.7 1 1 2 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region USP7_C2 PF14533.1 ETO10883.1 - 0.13 11.6 0.1 4.2 6.7 0.1 2.6 3 0 0 3 3 3 0 Ubiquitin-specific protease C-terminal DUF2527 PF10736.4 ETO10883.1 - 0.14 11.7 0.1 2.9 7.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) Kelch_2 PF07646.10 ETO10884.1 - 6.2e-05 22.6 1.3 0.087 12.6 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 ETO10884.1 - 0.013 15.0 0.4 1.5 8.4 0.0 3.1 3 0 0 3 3 3 0 Kelch motif PCI PF01399.22 ETO10885.1 - 3.2e-06 27.3 0.7 3.2e-06 27.3 0.5 2.8 3 1 0 3 3 3 1 PCI domain Myc_N PF01056.13 ETO10885.1 - 2 7.5 15.7 3.2 6.8 10.9 1.2 1 0 0 1 1 1 0 Myc amino-terminal region BSP_II PF05432.6 ETO10885.1 - 3.3 6.9 19.8 5.1 6.2 13.7 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) zf-TRAF PF02176.13 ETO10886.1 - 0.0096 16.2 6.4 0.0096 16.2 4.4 2.7 2 1 1 3 3 3 1 TRAF-type zinc finger DUF912 PF06024.7 ETO10887.1 - 0.0039 17.1 1.2 0.0039 17.1 0.8 4.4 2 2 1 3 3 3 2 Nucleopolyhedrovirus protein of unknown function (DUF912) TMEM51 PF15345.1 ETO10887.1 - 0.026 14.2 0.0 0.06 13.0 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 51 WD40 PF00400.27 ETO10888.1 - 5.9e-15 54.4 3.0 3.2e-10 39.4 0.4 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat zf-TRAF PF02176.13 ETO10888.1 - 2.2e-06 27.9 1.3 2.2e-06 27.9 0.9 2.1 2 0 0 2 2 2 1 TRAF-type zinc finger Nup160 PF11715.3 ETO10888.1 - 4.4e-05 21.8 0.3 7.6e-05 21.0 0.2 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 V-ATPase_G PF03179.10 ETO10888.1 - 0.48 10.7 14.0 0.33 11.2 7.8 2.1 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit TSC22 PF01166.13 ETO10889.1 - 0.39 10.7 0.2 0.39 10.7 0.1 3.4 2 1 1 3 3 3 0 TSC-22/dip/bun family Cob_adeno_trans PF01923.13 ETO10889.1 - 0.72 9.6 6.8 0.15 11.8 1.3 2.0 1 1 1 2 2 2 0 Cobalamin adenosyltransferase ALMT PF11744.3 ETO10891.1 - 1.1 7.8 4.7 2 6.9 3.2 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF3086 PF11285.3 ETO10892.1 - 0.028 13.2 0.3 0.034 12.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) DUF641 PF04859.7 ETO10892.1 - 0.049 13.3 1.1 0.084 12.6 0.8 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) FlgN PF05130.7 ETO10892.1 - 0.056 13.6 1.1 0.08 13.1 0.8 1.1 1 0 0 1 1 1 0 FlgN protein DUF3713 PF12506.3 ETO10892.1 - 0.13 12.3 0.6 5.7 7.0 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3713) DUF3782 PF12644.2 ETO10892.1 - 0.63 9.8 3.3 2.1 8.1 2.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) Dicty_REP PF05086.7 ETO10896.1 - 0.0065 14.3 15.5 0.0082 13.9 10.8 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 ETO10896.1 - 0.014 15.1 1.3 0.031 14.0 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) AAA_18 PF13238.1 ETO10896.1 - 0.023 15.0 0.1 0.061 13.6 0.1 1.7 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.15 ETO10896.1 - 0.19 10.4 13.5 0.42 9.2 9.4 1.7 1 1 0 1 1 1 0 G-protein alpha subunit Mucin PF01456.12 ETO10896.1 - 0.64 9.7 13.4 0.27 11.0 7.4 1.7 1 1 1 2 2 2 0 Mucin-like glycoprotein Helicase_Sgs1 PF11408.3 ETO10899.1 - 0.044 13.6 0.1 0.09 12.6 0.0 1.6 1 1 0 1 1 1 0 Sgs1 RecQ helicase TraV PF09676.5 ETO10901.1 - 0.0071 17.0 0.1 0.011 16.4 0.1 1.2 1 0 0 1 1 1 1 Type IV conjugative transfer system lipoprotein (TraV) DUF1675 PF07897.6 ETO10901.1 - 0.03 14.2 0.8 0.038 13.8 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) NST1 PF13945.1 ETO10901.1 - 0.034 14.2 4.4 0.044 13.8 3.0 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator U-box PF04564.10 ETO10902.1 - 1.2e-06 28.3 2.5 4.4e-06 26.5 0.2 2.9 2 1 0 2 2 2 1 U-box domain Abhydrolase_6 PF12697.2 ETO10903.1 - 0.0033 17.3 0.0 0.0034 17.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2203 PF09969.4 ETO10905.1 - 0.069 13.3 0.2 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Minor_capsid_1 PF10665.4 ETO10905.1 - 0.088 12.6 1.1 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Minor capsid protein DUF2344 PF10105.4 ETO10906.1 - 0.00028 20.4 1.8 0.00064 19.2 1.3 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2344) WD40 PF00400.27 ETO10907.1 - 8.6e-69 225.1 24.4 1.6e-11 43.6 0.5 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO10907.1 - 2.8e-12 45.5 3.6 0.00013 20.2 0.0 4.7 2 1 2 4 4 4 3 Nucleoporin Nup120/160 DUF4460 PF14687.1 ETO10908.1 - 0.0089 15.7 0.3 0.15 11.7 0.2 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4460) RasGEF PF00617.14 ETO10909.1 - 4.5e-17 62.3 0.2 2.2e-16 60.1 0.1 2.1 1 1 0 1 1 1 1 RasGEF domain YppF PF14178.1 ETO10909.1 - 0.02 14.4 0.0 0.078 12.5 0.0 2.1 2 0 0 2 2 2 0 YppF-like protein adh_short PF00106.20 ETO10910.1 - 8.1e-08 32.3 0.1 1.4e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETO10910.1 - 0.0074 15.9 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 ETO10910.1 - 0.0092 15.1 0.1 0.066 12.3 0.0 1.9 1 1 0 2 2 2 1 Fungal family of unknown function (DUF1776) Aminotran_1_2 PF00155.16 ETO10911.1 - 1.3e-17 63.8 0.0 3.3e-17 62.4 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 ETO10911.1 - 0.026 13.0 0.0 0.053 12.0 0.0 1.4 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase DUF2457 PF10446.4 ETO10911.1 - 2.6 6.6 6.4 0.22 10.1 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) DUF912 PF06024.7 ETO10911.1 - 7.5 6.6 8.8 0.98 9.5 1.6 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) BUD22 PF09073.5 ETO10912.1 - 0.2 10.7 33.5 0.24 10.4 23.2 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 ETO10912.1 - 0.25 9.2 28.0 0.33 8.8 19.4 1.1 1 0 0 1 1 1 0 Nop14-like family TATR PF03430.8 ETO10912.1 - 1.3 7.5 17.2 1.6 7.2 11.9 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Serinc PF03348.10 ETO10912.1 - 2.1 6.9 7.8 7 5.2 5.4 1.8 1 1 0 1 1 1 0 Serine incorporator (Serinc) SRP-alpha_N PF04086.8 ETO10912.1 - 3.8 6.8 28.2 6.6 6.0 19.5 1.5 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal U79_P34 PF03064.11 ETO10912.1 - 9.5 5.6 25.4 15 4.9 17.6 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 TPR_11 PF13414.1 ETO10913.1 - 6.5e-09 35.3 0.0 0.0002 20.9 0.0 2.6 1 1 1 2 2 2 2 TPR repeat TPR_16 PF13432.1 ETO10913.1 - 1.5e-06 28.6 0.0 0.018 15.7 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO10913.1 - 2.3e-05 24.6 0.3 0.094 13.0 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO10913.1 - 0.0096 16.0 0.1 4.9 7.6 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF2457 PF10446.4 ETO10914.1 - 0.024 13.4 4.7 0.035 12.8 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CAF-1_p150 PF11600.3 ETO10915.1 - 1.8 7.8 53.9 0.25 10.6 23.1 2.8 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CAP_GLY PF01302.20 ETO10916.1 - 1.7e-20 72.4 0.3 5.4e-13 48.4 0.0 3.2 3 0 0 3 3 3 3 CAP-Gly domain Ank_2 PF12796.2 ETO10917.1 - 0.0011 19.2 0.0 0.004 17.4 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO10917.1 - 0.12 12.6 0.0 5.9 7.2 0.0 3.2 4 0 0 4 4 4 0 Ankyrin repeats (many copies) AAA PF00004.24 ETO10918.1 - 0.00014 22.0 0.0 0.0016 18.6 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETO10918.1 - 0.0046 16.6 0.0 0.024 14.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETO10918.1 - 0.015 15.4 0.0 4.5 7.4 0.0 2.8 2 1 1 3 3 3 0 AAA domain PQQ PF01011.16 ETO10919.1 - 1.5e-10 40.0 0.8 1.4e-05 24.3 0.0 4.8 5 0 0 5 5 5 2 PQQ enzyme repeat PQQ_3 PF13570.1 ETO10919.1 - 4e-06 26.9 0.8 0.15 12.4 0.0 3.9 3 1 1 4 4 4 2 PQQ-like domain PQQ_2 PF13360.1 ETO10919.1 - 1.7e-05 24.4 0.0 0.00013 21.4 0.0 2.2 1 1 1 2 2 2 1 PQQ-like domain PAT1 PF09770.4 ETO10920.1 - 0.23 9.6 37.9 0.3 9.2 26.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 ETO10920.1 - 2.9 7.6 43.4 0.098 12.5 26.2 1.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CENP-T PF15511.1 ETO10920.1 - 7.1 5.7 30.2 11 5.1 20.9 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CPSF100_C PF13299.1 ETO10921.1 - 0.067 13.3 2.2 0.16 12.1 1.5 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Mito_fiss_reg PF05308.6 ETO10921.1 - 1.4 8.1 16.1 0.038 13.3 6.0 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator Pex14_N PF04695.8 ETO10921.1 - 3.1 7.8 10.9 0.62 10.1 0.8 2.9 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CAP_GLY PF01302.20 ETO10922.1 - 1.5e-14 53.4 0.1 2.6e-14 52.6 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF842 PF05811.8 ETO10923.1 - 0.58 9.6 4.7 0.08 12.3 0.4 1.7 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) 7tm_7 PF08395.7 ETO10924.1 - 0.0011 18.0 5.0 0.0015 17.5 3.5 1.1 1 0 0 1 1 1 1 7tm Chemosensory receptor Pex24p PF06398.6 ETO10924.1 - 0.0048 15.7 0.2 0.0048 15.7 0.1 2.4 2 1 0 2 2 2 1 Integral peroxisomal membrane peroxin DUF2628 PF10947.3 ETO10924.1 - 0.0056 16.4 0.1 0.015 15.1 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2628) LMBR1 PF04791.11 ETO10924.1 - 0.01 14.4 3.2 0.015 13.9 2.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2681 PF10883.3 ETO10924.1 - 0.021 15.0 1.2 0.021 15.0 0.8 4.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2681) Yippee-Mis18 PF03226.9 ETO10924.1 - 0.045 13.7 0.7 0.045 13.7 0.5 2.1 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF1510 PF07423.6 ETO10924.1 - 0.4 10.0 22.8 2.7 7.3 15.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Rtf2 PF04641.7 ETO10924.1 - 0.55 9.3 31.8 0.53 9.4 18.0 2.8 1 1 2 3 3 3 0 Rtf2 RING-finger DUF2718 PF10918.3 ETO10924.1 - 0.79 9.7 7.3 1.2 9.1 4.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2718) zf-met PF12874.2 ETO10924.1 - 4.1 7.7 8.2 1 9.6 3.1 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type RtcB PF01139.12 ETO10925.1 - 1.3e-141 472.4 1.5 1.7e-141 472.0 1.0 1.1 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB UvrD_C PF13361.1 ETO10927.1 - 0.017 14.5 1.3 0.021 14.2 0.9 1.1 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain RNA_pol_A_bac PF01000.21 ETO10928.1 - 4.7e-11 42.8 0.0 2.5e-10 40.4 0.0 2.2 2 1 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain Fer4_7 PF12838.2 ETO10928.1 - 0.013 15.8 0.5 0.031 14.6 0.3 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Striatin PF08232.7 ETO10928.1 - 0.25 11.6 2.6 0.36 11.1 1.8 1.2 1 0 0 1 1 1 0 Striatin family HTH_Tnp_Tc3_1 PF11427.3 ETO10928.1 - 0.8 9.3 3.2 2.4 7.8 0.0 3.1 3 1 0 3 3 3 0 Tc3 transposase WD40 PF00400.27 ETO10930.1 - 1e-109 354.9 21.1 5e-11 42.0 0.2 14.0 14 0 0 14 14 14 13 WD domain, G-beta repeat NACHT PF05729.7 ETO10930.1 - 1.2e-07 31.5 0.0 4.3e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 NACHT domain Pentapeptide PF00805.17 ETO10930.1 - 1.5e-06 27.2 0.8 3.9e-06 25.9 0.6 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) AAA_18 PF13238.1 ETO10930.1 - 9.8e-06 25.8 2.4 3.4e-05 24.1 0.1 3.1 2 0 0 2 2 2 1 AAA domain PQQ_2 PF13360.1 ETO10930.1 - 6.9e-05 22.4 0.1 0.031 13.7 0.0 3.3 3 1 0 3 3 3 1 PQQ-like domain Pentapeptide_3 PF13576.1 ETO10930.1 - 0.00018 21.3 1.2 0.00018 21.3 0.9 2.0 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.1 ETO10930.1 - 0.00019 21.1 1.4 0.00059 19.5 1.0 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA_17 PF13207.1 ETO10930.1 - 0.00034 21.4 0.1 0.0038 18.0 0.0 2.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ETO10930.1 - 0.0032 17.6 0.0 0.013 15.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain PD40 PF07676.7 ETO10930.1 - 0.038 13.6 4.5 0.3 10.8 0.1 4.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Chorein_N PF12624.2 ETO10931.1 - 1.8e-26 91.9 0.1 2.1e-26 91.7 0.1 1.0 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ComJ PF11033.3 ETO10932.1 - 0.032 13.8 0.4 0.068 12.8 0.0 1.8 2 0 0 2 2 2 0 Competence protein J (ComJ) PWWP PF00855.12 ETO10932.1 - 0.036 14.2 0.6 0.34 11.1 0.4 2.4 2 0 0 2 2 2 0 PWWP domain DUF1788 PF08747.6 ETO10932.1 - 0.084 12.7 1.8 0.13 12.1 0.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1788) DUF4497 PF14924.1 ETO10932.1 - 0.26 11.5 2.7 0.23 11.8 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) ARF7EP_C PF14949.1 ETO10932.1 - 5 7.6 7.4 0.32 11.4 0.8 2.2 3 0 0 3 3 3 0 ARF7 effector protein C-terminus Dymeclin PF09742.4 ETO10933.1 - 0.036 12.1 0.0 0.04 12.0 0.0 1.0 1 0 0 1 1 1 0 Dyggve-Melchior-Clausen syndrome protein Ion_trans PF00520.26 ETO10933.1 - 0.077 12.2 0.1 0.098 11.8 0.1 1.1 1 0 0 1 1 1 0 Ion transport protein Tic20 PF09685.5 ETO10933.1 - 0.14 12.1 0.7 1.9 8.5 0.1 2.2 2 0 0 2 2 2 0 Tic20-like protein DUF2217 PF10265.4 ETO10934.1 - 5.1 5.7 9.5 0.28 9.9 2.6 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) Pkinase PF00069.20 ETO10935.1 - 1.2e-67 227.8 0.4 3.3e-67 226.3 0.3 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO10935.1 - 9.6e-40 136.2 0.7 1.3e-39 135.8 0.1 1.6 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO10935.1 - 1.4e-08 34.0 0.0 2.4e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 ETO10935.1 - 0.00045 19.6 0.1 0.00085 18.7 0.1 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 ETO10935.1 - 0.0018 18.0 0.0 0.0029 17.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 ETO10935.1 - 0.017 14.2 0.1 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.4 ETO10935.1 - 0.018 13.6 0.1 0.029 12.9 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC YrbL-PhoP_reg PF10707.4 ETO10935.1 - 0.024 13.9 0.4 0.045 13.0 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DUF1345 PF07077.6 ETO10935.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) BLVR PF06375.6 ETO10936.1 - 0.029 14.1 13.4 0.46 10.3 4.3 2.2 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) DUF1764 PF08576.5 ETO10936.1 - 2.8 8.7 13.1 3.5 8.4 4.0 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Polysacc_synt PF01943.12 ETO10936.1 - 4 6.6 11.9 3.1 6.9 5.5 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein AUX_IAA PF02309.11 ETO10937.1 - 2 8.1 11.0 0.027 14.2 1.4 2.1 2 0 0 2 2 2 0 AUX/IAA family Rieske PF00355.21 ETO10938.1 - 6.9e-06 25.5 0.6 4.4e-05 22.9 0.4 2.1 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain DUF3801 PF12687.2 ETO10941.1 - 0.14 11.7 19.6 0.16 11.5 13.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) RNase_H2-Ydr279 PF09468.5 ETO10941.1 - 2.5 7.2 17.1 2.7 7.1 11.9 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) U79_P34 PF03064.11 ETO10941.1 - 4.3 6.7 13.7 4.4 6.7 9.5 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 PBP_sp32 PF07222.7 ETO10941.1 - 5.9 5.9 8.6 6.4 5.8 6.0 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 WD40 PF00400.27 ETO10942.1 - 1.7e-29 100.5 11.7 4.7e-08 32.6 0.1 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO10942.1 - 5.1e-07 28.2 0.7 0.065 11.3 0.0 3.4 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Peptidase_M50 PF02163.17 ETO10942.1 - 0.14 11.1 1.3 0.44 9.4 0.0 2.1 2 0 0 2 2 2 0 Peptidase family M50 PAM2 PF07145.10 ETO10944.1 - 0.0012 18.2 3.7 0.0026 17.1 2.6 1.6 1 0 0 1 1 1 1 Ataxin-2 C-terminal region Choline_kinase PF01633.15 ETO10945.1 - 0.27 10.7 3.2 0.32 10.5 2.2 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase Methyltransf_16 PF10294.4 ETO10946.1 - 0.011 15.1 0.4 0.022 14.1 0.2 1.5 1 0 0 1 1 1 0 Putative methyltransferase DUF2458 PF10454.4 ETO10946.1 - 0.018 14.8 1.7 0.041 13.7 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) DUF325 PF03804.8 ETO10946.1 - 0.025 14.2 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 Viral domain of unknown function Mfa2 PF08842.5 ETO10948.1 - 0.038 13.3 0.3 0.049 12.9 0.2 1.3 1 1 0 1 1 1 0 Fimbrillin-A associated anchor proteins Mfa1 and Mfa2 Mhr1 PF12829.2 ETO10949.1 - 0.084 12.7 0.8 0.12 12.2 0.6 1.2 1 0 0 1 1 1 0 Transcriptional regulation of mitochondrial recombination WD40 PF00400.27 ETO10950.1 - 1.1e-19 69.4 2.6 2.8e-11 42.8 0.1 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO10950.1 - 0.011 13.8 0.0 0.33 9.0 0.0 2.0 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO10950.1 - 0.021 13.5 0.3 0.57 8.8 0.2 2.0 1 1 0 1 1 1 0 Nup133 N terminal like DUF2457 PF10446.4 ETO10951.1 - 0.006 15.3 10.8 0.0078 14.9 7.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) TFIIF_alpha PF05793.7 ETO10951.1 - 0.084 11.2 14.4 0.12 10.6 10.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Mga PF05043.8 ETO10951.1 - 1.5 9.1 7.0 0.28 11.5 0.8 2.2 2 0 0 2 2 2 0 Mga helix-turn-helix domain Cwf_Cwc_15 PF04889.7 ETO10951.1 - 3.6 7.2 23.3 7 6.2 16.2 1.5 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Trypan_PARP PF05887.6 ETO10951.1 - 6.4 6.5 6.2 11 5.7 4.3 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Daxx PF03344.10 ETO10952.1 - 0.84 8.0 23.5 1 7.7 16.3 1.0 1 0 0 1 1 1 0 Daxx Family FAM176 PF14851.1 ETO10952.1 - 8.6 6.0 14.9 2.9 7.5 2.8 2.3 2 0 0 2 2 2 0 FAM176 family DUF1659 PF07872.6 ETO10953.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1659) DUF706 PF05153.10 ETO10954.1 - 8.6e-65 218.5 2.6 1.4e-64 217.8 1.8 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF706) HDOD PF08668.7 ETO10954.1 - 0.017 14.4 0.0 0.031 13.5 0.0 1.4 1 0 0 1 1 1 0 HDOD domain HD PF01966.17 ETO10954.1 - 0.044 13.7 0.3 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 HD domain TORC_C PF12886.2 ETO10955.1 - 0.12 12.6 0.0 0.43 10.7 0.0 2.0 1 1 1 2 2 2 0 Transducer of regulated CREB activity, C terminus WD40 PF00400.27 ETO10957.1 - 3.4e-13 48.9 7.9 2.2e-12 46.3 0.9 3.0 3 1 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO10957.1 - 0.0099 14.0 0.1 0.045 11.8 0.0 1.9 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO10957.1 - 5 7.4 5.5 7.2 6.9 0.3 2.7 2 1 1 3 3 3 0 Kelch motif Raptor_N PF14538.1 ETO10962.1 - 0.081 12.7 4.5 0.29 10.9 3.1 2.0 1 1 0 1 1 1 0 Raptor N-terminal CASPase like domain YejG PF13989.1 ETO10962.1 - 0.37 10.8 3.5 0.39 10.7 0.9 2.0 1 1 0 2 2 2 0 YejG-like protein DnaJ PF00226.26 ETO10963.1 - 1.4e-13 50.3 2.8 8.4e-09 35.0 0.9 2.3 2 0 0 2 2 2 2 DnaJ domain 2OG-Fe_Oxy_2 PF10014.4 ETO10963.1 - 0.23 10.8 2.5 0.4 10.0 1.7 1.3 1 0 0 1 1 1 0 2OG-Fe dioxygenase PNP_UDP_1 PF01048.15 ETO10964.1 - 0.023 13.7 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 Phosphorylase superfamily Ribosomal_S10 PF00338.17 ETO10964.1 - 0.032 14.0 1.2 0.084 12.7 0.7 1.8 1 1 0 1 1 1 0 Ribosomal protein S10p/S20e DUF4130 PF13566.1 ETO10964.1 - 0.099 12.1 1.3 0.21 11.1 0.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4130 Kelch_6 PF13964.1 ETO10967.1 - 0.003 17.6 0.9 0.1 12.7 0.0 2.8 3 0 0 3 3 3 1 Kelch motif Choline_sulf_C PF12411.3 ETO10968.1 - 0.09 12.6 1.4 0.12 12.2 0.2 1.8 2 0 0 2 2 2 0 Choline sulfatase enzyme C terminal RNA_binding PF01877.12 ETO10969.1 - 0.00072 19.5 3.4 0.0077 16.2 0.9 2.0 1 1 1 2 2 2 1 RNA binding PB1 PF00564.19 ETO10969.1 - 0.016 14.8 0.3 0.33 10.6 0.1 2.1 2 0 0 2 2 2 0 PB1 domain Tol_Tol_Ttg2 PF05494.7 ETO10969.1 - 0.021 14.3 0.6 0.021 14.3 0.4 1.1 1 0 0 1 1 1 0 Toluene tolerance, Ttg2 Dimeth_Pyl PF09505.5 ETO10969.1 - 0.026 12.8 0.2 0.027 12.7 0.1 1.1 1 0 0 1 1 1 0 Dimethylamine methyltransferase (Dimeth_PyL) UPF0223 PF05256.7 ETO10969.1 - 0.027 14.5 1.1 0.58 10.3 0.0 2.6 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0223) FPL PF09758.4 ETO10969.1 - 0.041 13.6 4.0 0.18 11.5 0.7 2.5 1 1 2 3 3 3 0 Uncharacterised conserved protein Ndc80_HEC PF03801.8 ETO10969.1 - 0.092 12.1 0.9 0.37 10.1 0.1 1.9 1 1 1 2 2 2 0 HEC/Ndc80p family CLTH PF10607.4 ETO10969.1 - 0.35 10.5 5.1 0.59 9.8 3.5 1.4 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain VWA_2 PF13519.1 ETO10970.1 - 6.1e-06 26.4 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 ETO10970.1 - 0.0026 17.5 0.3 0.68 9.6 0.0 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_CoxE PF05762.9 ETO10970.1 - 0.059 12.4 0.1 5.3 6.1 0.0 2.2 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein Ssl1 PF04056.9 ETO10970.1 - 0.068 12.7 0.2 2.5 7.6 0.0 2.3 2 0 0 2 2 2 0 Ssl1-like Orthopox_F14 PF06076.7 ETO10972.1 - 0.086 12.9 1.9 0.16 12.0 1.3 1.4 1 0 0 1 1 1 0 Orthopoxvirus F14 protein Macoilin PF09726.4 ETO10972.1 - 6 5.0 18.1 7.4 4.7 12.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Kelch_6 PF13964.1 ETO10973.1 - 3.1e-06 27.0 6.2 0.00032 20.7 0.0 3.9 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO10973.1 - 1.5e-05 24.5 1.5 0.085 12.6 0.0 4.8 5 0 0 5 5 5 1 Kelch motif Kelch_5 PF13854.1 ETO10973.1 - 1.8e-05 24.5 1.1 0.014 15.3 0.1 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.20 ETO10973.1 - 4e-05 23.0 5.2 0.005 16.3 0.0 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO10973.1 - 4.4e-05 23.1 0.1 0.0061 16.3 0.0 2.9 1 1 1 2 2 2 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO10973.1 - 0.00019 21.5 0.0 0.0054 16.8 0.0 2.9 3 0 0 3 3 3 1 Galactose oxidase, central domain Toprim_3 PF13362.1 ETO10974.1 - 1.2e-19 70.3 0.1 4.6e-19 68.4 0.1 2.1 1 0 0 1 1 1 1 Toprim domain UvrD_C_2 PF13538.1 ETO10974.1 - 3.9e-08 33.3 0.4 3.3e-07 30.3 0.1 2.9 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Toprim_2 PF13155.1 ETO10974.1 - 0.00026 21.2 0.4 0.0017 18.6 0.0 2.7 2 0 0 2 2 2 1 Toprim-like Toprim_4 PF13662.1 ETO10974.1 - 0.00083 19.3 0.0 0.0022 17.9 0.0 1.7 1 0 0 1 1 1 1 Toprim domain Coa1 PF08695.5 ETO10974.1 - 0.053 13.0 0.1 9.4 5.7 0.0 2.7 2 0 0 2 2 2 0 Cytochrome oxidase complex assembly protein 1 WD40 PF00400.27 ETO10975.1 - 1.7e-88 287.6 24.4 2.8e-13 49.1 0.1 9.0 9 0 0 9 9 9 9 WD domain, G-beta repeat Nup160 PF11715.3 ETO10975.1 - 1.2e-10 40.2 9.5 0.038 12.1 0.1 7.0 1 1 6 7 7 7 4 Nucleoporin Nup120/160 PD40 PF07676.7 ETO10975.1 - 5.1e-06 26.0 5.7 5.2 6.8 0.1 5.9 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 ETO10975.1 - 1.8e-05 24.0 3.8 0.23 10.5 0.0 4.6 2 2 2 5 5 5 2 Neuroblastoma-amplified sequence, N terminal DUF1938 PF09153.5 ETO10975.1 - 0.00014 21.5 0.2 0.055 13.2 0.0 3.2 3 1 1 4 4 4 1 Domain of unknown function (DUF1938) DUF1258 PF06869.7 ETO10975.1 - 0.0034 16.4 0.6 2.8 6.9 0.1 3.7 3 1 1 4 4 4 1 Protein of unknown function (DUF1258) NYD-SP28_assoc PF14775.1 ETO10975.1 - 0.0036 16.9 5.1 9.8 5.9 0.0 6.2 7 1 1 8 8 8 1 Sperm tail C-terminal domain SGL PF08450.7 ETO10975.1 - 0.0037 16.6 0.1 0.1 11.9 0.0 2.8 1 1 0 3 3 3 1 SMP-30/Gluconolaconase/LRE-like region PQQ_2 PF13360.1 ETO10975.1 - 0.0045 16.4 0.5 0.12 11.8 0.4 2.7 1 1 0 1 1 1 1 PQQ-like domain Mid2 PF04478.7 ETO10975.1 - 0.019 14.3 4.1 3.6 6.9 0.0 4.5 2 2 3 5 5 5 0 Mid2 like cell wall stress sensor Cytochrom_D1 PF02239.11 ETO10975.1 - 0.053 11.8 0.3 0.18 10.0 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain BLUF PF04940.7 ETO10975.1 - 0.073 12.7 0.0 28 4.5 0.0 3.6 4 0 0 4 4 4 0 Sensors of blue-light using FAD Pectate_lyase22 PF14583.1 ETO10975.1 - 0.075 11.4 0.0 0.43 8.9 0.0 2.1 2 1 1 3 3 3 0 Oligogalacturonate lyase SecA_DEAD PF07517.9 ETO10976.1 - 1.8e-09 37.2 0.0 6.6e-09 35.4 0.0 2.0 1 1 0 1 1 1 1 SecA DEAD-like domain RhoGEF PF00621.15 ETO10979.1 - 6e-08 32.7 1.9 7.9e-07 29.1 1.3 2.0 1 1 0 1 1 1 1 RhoGEF domain Exonuc_V_gamma PF04257.9 ETO10979.1 - 0.049 11.6 0.1 0.053 11.5 0.0 1.0 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit Glycos_trans_3N PF02885.12 ETO10979.1 - 0.12 11.9 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain Kelch_6 PF13964.1 ETO10980.1 - 4.5e-10 39.2 4.7 0.00046 20.2 0.1 4.7 4 1 1 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO10980.1 - 3.5e-08 32.8 7.1 0.00032 20.1 0.1 3.8 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 ETO10980.1 - 3.3e-07 30.1 6.3 0.045 13.7 0.3 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO10980.1 - 1.1e-06 28.0 2.7 0.014 15.1 0.0 4.1 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 ETO10980.1 - 0.0001 22.3 0.3 0.0014 18.7 0.1 2.9 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO10980.1 - 0.00027 20.6 1.6 0.0019 17.9 0.1 3.1 4 0 0 4 4 4 1 Galactose oxidase, central domain N_Asn_amidohyd PF14736.1 ETO10980.1 - 0.011 14.6 0.2 0.31 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein N-terminal asparagine amidohydrolase TP53IP5 PF15331.1 ETO10981.1 - 0.06 13.2 3.8 0.11 12.4 2.7 1.4 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 zf-RING_UBOX PF13445.1 ETO10981.1 - 0.067 12.9 4.5 0.082 12.6 1.4 2.5 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 ETO10981.1 - 5.8 7.0 19.3 0.063 13.3 6.2 2.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) NAD_binding_10 PF13460.1 ETO10982.1 - 0.06 13.3 0.1 0.081 12.9 0.1 1.1 1 0 0 1 1 1 0 NADH(P)-binding Phe_hydrox_dim PF07976.7 ETO10982.1 - 0.1 12.2 0.2 1.7 8.2 0.0 2.0 1 1 1 2 2 2 0 Phenol hydroxylase, C-terminal dimerisation domain YodL PF14191.1 ETO10982.1 - 0.22 12.0 3.3 0.21 12.0 0.8 2.0 1 1 2 3 3 3 0 YodL-like RNA_pol_Rpb1_5 PF04998.12 ETO10983.1 - 0.43 9.7 2.8 0.45 9.7 1.9 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF2569 PF10754.4 ETO10984.1 - 0.032 14.4 0.7 0.062 13.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) ICAP-1_inte_bdg PF10480.4 ETO10984.1 - 0.099 12.4 0.0 0.39 10.4 0.0 1.9 2 1 0 2 2 2 0 Beta-1 integrin binding protein TMCO5 PF14992.1 ETO10986.1 - 0.37 9.8 11.6 0.38 9.8 8.0 1.1 1 0 0 1 1 1 0 TMCO5 family UPF0515 PF15135.1 ETO10986.1 - 0.4 9.6 2.2 0.6 9.1 1.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 Microtub_assoc PF07989.6 ETO10986.1 - 0.5 10.2 11.4 1.7 8.5 3.6 2.6 1 1 1 2 2 2 0 Microtubule associated MxiH PF09392.5 ETO10986.1 - 0.52 10.9 3.4 0.43 11.1 0.4 2.2 3 0 0 3 3 3 0 Type III secretion needle MxiH like LRS4 PF10422.4 ETO10986.1 - 2 7.7 13.5 2.5 7.3 9.4 1.3 1 1 0 1 1 1 0 Monopolin complex subunit LRS4 DUF972 PF06156.8 ETO10986.1 - 5.4 7.3 11.4 8.2 6.8 6.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) EF-hand_1 PF00036.27 ETO10988.1 - 4.1e-15 53.8 0.4 3.8e-06 25.8 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 ETO10988.1 - 7.5e-14 51.6 1.3 1.1e-13 51.0 0.1 1.9 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO10988.1 - 1e-11 43.6 1.9 4.7e-05 22.9 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 ETO10988.1 - 5.2e-11 41.3 2.0 0.00012 21.2 0.0 2.8 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 ETO10988.1 - 9.7e-08 31.5 0.0 3.8e-07 29.6 0.0 2.1 1 1 0 1 1 1 1 EF-hand domain pair SPARC_Ca_bdg PF10591.4 ETO10988.1 - 0.015 15.2 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region FDX-ACB PF03147.9 ETO10988.1 - 0.025 14.7 0.5 1.6 8.9 0.0 2.8 2 1 1 3 3 3 0 Ferredoxin-fold anticodon binding domain EF-hand_4 PF12763.2 ETO10988.1 - 0.097 12.4 0.3 0.21 11.3 0.1 1.8 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand PMBR PF09373.5 ETO10988.1 - 0.12 12.3 0.2 3 7.9 0.0 2.8 3 0 0 3 3 3 0 Pseudomurein-binding repeat OAD_gamma PF04277.8 ETO10989.1 - 0.23 11.8 1.7 0.33 11.3 0.3 1.8 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Phage_XkdX PF09693.5 ETO10989.1 - 0.39 10.2 3.6 0.25 10.8 0.4 2.3 2 0 0 2 2 2 0 Phage uncharacterised protein (Phage_XkdX) Translat_reg PF01818.12 ETO10989.1 - 0.93 9.0 5.6 0.31 10.5 1.2 2.1 3 0 0 3 3 3 0 Bacteriophage translational regulator MutL_C PF08676.6 ETO10990.1 - 2.8e-20 72.4 0.0 4.8e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 MutL C terminal dimerisation domain Pkinase PF00069.20 ETO10992.1 - 1.4e-45 155.4 1.9 5.5e-43 146.9 1.3 3.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO10992.1 - 2e-22 79.5 0.8 1.8e-21 76.3 0.5 2.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO10992.1 - 7.1e-07 28.4 0.1 2.7e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.19 ETO10992.1 - 0.015 15.8 0.8 0.031 14.7 0.5 1.6 1 0 0 1 1 1 0 Protein kinase C terminal domain APH PF01636.18 ETO10992.1 - 0.033 13.9 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 ETO10992.1 - 0.057 12.2 0.1 0.16 10.7 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 Helicase_C PF00271.26 ETO10993.1 - 4.4e-10 39.2 0.2 1.2e-09 37.9 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PIG-X PF08320.7 ETO10993.1 - 0.03 13.6 0.1 0.038 13.2 0.1 1.1 1 0 0 1 1 1 0 PIG-X / PBN1 Tudor-knot PF11717.3 ETO10994.1 - 0.017 14.8 0.6 0.037 13.7 0.4 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain AAA_11 PF13086.1 ETO10995.1 - 2.2e-27 96.1 0.1 2.2e-27 96.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 ETO10995.1 - 3.3e-26 91.9 0.0 3.3e-26 91.9 0.0 4.0 4 0 0 4 4 3 1 AAA domain AAA_19 PF13245.1 ETO10995.1 - 1.1e-08 34.7 0.0 3.2e-08 33.2 0.0 1.7 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 ETO10995.1 - 5.7e-06 26.0 0.1 0.039 13.5 0.0 2.9 3 0 0 3 3 3 2 AAA domain SAPS PF04499.10 ETO10995.1 - 8.9e-05 21.2 15.0 0.00017 20.3 10.4 1.3 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein CCDC66 PF15236.1 ETO10995.1 - 0.0001 21.9 18.3 0.00024 20.7 12.7 1.6 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 66 DEAD PF00270.24 ETO10995.1 - 0.00047 19.6 0.5 0.0015 18.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase TFIIF_alpha PF05793.7 ETO10995.1 - 0.001 17.5 21.0 0.0018 16.7 14.5 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) AAA PF00004.24 ETO10995.1 - 0.0011 19.2 0.1 0.014 15.6 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETO10995.1 - 0.0023 18.0 1.5 0.0092 16.1 0.0 2.8 4 0 0 4 4 4 1 AAA domain Viral_helicase1 PF01443.13 ETO10995.1 - 0.0027 17.2 3.8 0.98 8.8 0.0 3.8 4 0 0 4 4 3 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 ETO10995.1 - 0.0045 16.4 0.0 0.012 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF572 PF04502.8 ETO10995.1 - 0.079 12.1 23.1 0.16 11.1 16.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Exo_endo_phos PF03372.18 ETO10996.1 - 8.4e-10 38.9 0.3 1.3e-09 38.4 0.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2719 PF10891.3 ETO10996.1 - 0.025 14.2 0.1 0.09 12.4 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2719) Ku_C PF03730.9 ETO10996.1 - 0.032 14.7 0.8 0.087 13.3 0.0 2.1 2 1 0 2 2 2 0 Ku70/Ku80 C-terminal arm DUF3069 PF11269.3 ETO10996.1 - 0.13 12.3 1.3 7.6 6.6 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3069) MRP-S33 PF08293.6 ETO10997.1 - 0.00044 20.1 1.6 0.00093 19.1 1.1 1.7 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 DUF3825 PF12873.2 ETO10997.1 - 0.053 12.6 0.1 0.053 12.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3825) EamA PF00892.15 ETO10998.1 - 1.7 8.7 21.3 0.14 12.1 8.4 2.7 1 1 2 3 3 3 0 EamA-like transporter family WD40 PF00400.27 ETO10999.1 - 1.8e-78 255.8 19.9 3.2e-14 52.1 0.1 7.2 6 1 1 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO10999.1 - 2.1e-07 30.8 0.0 0.07 12.8 0.0 3.4 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO10999.1 - 3.9e-07 28.5 1.3 0.065 11.3 0.1 5.1 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 ETO10999.1 - 5.8e-05 22.3 1.3 2.7 7.0 0.0 4.4 1 1 3 5 5 5 2 Neuroblastoma-amplified sequence, N terminal Pentapeptide PF00805.17 ETO10999.1 - 0.00047 19.3 0.2 0.0011 18.1 0.1 1.6 1 1 0 1 1 1 1 Pentapeptide repeats (8 copies) PD40 PF07676.7 ETO10999.1 - 0.0028 17.2 2.7 1.2 8.8 0.0 4.8 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Pentapeptide_4 PF13599.1 ETO10999.1 - 0.0099 15.6 0.6 0.024 14.4 0.4 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Nucleoporin_N PF08801.6 ETO10999.1 - 0.014 14.1 5.1 1.4 7.5 0.6 4.2 1 1 1 2 2 2 0 Nup133 N terminal like NYD-SP28_assoc PF14775.1 ETO10999.1 - 0.02 14.6 0.6 38 4.0 0.0 5.0 7 0 0 7 7 7 0 Sperm tail C-terminal domain Pentapeptide_3 PF13576.1 ETO10999.1 - 0.03 14.2 5.7 0.034 14.0 1.8 2.7 2 1 0 2 2 2 0 Pentapeptide repeats (9 copies) DUF727 PF05303.7 ETO10999.1 - 0.14 11.9 0.1 7.4 6.4 0.0 3.3 4 1 1 5 5 5 0 Protein of unknown function (DUF727) WD40 PF00400.27 ETO11000.1 - 1.1e-43 145.5 13.2 2.5e-12 46.1 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO11000.1 - 3.1e-08 32.2 1.4 0.0036 15.5 0.5 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO11000.1 - 0.035 14.0 0.0 1.3 9.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3601) Rsbr_N PF08678.5 ETO11002.1 - 0.012 15.4 0.8 0.085 12.7 0.2 2.1 2 0 0 2 2 2 0 Rsbr N terminal DUF2420 PF10336.4 ETO11002.1 - 0.068 12.7 0.8 0.14 11.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2420) Cofilin_ADF PF00241.15 ETO11002.1 - 0.075 12.9 0.3 0.14 12.0 0.2 1.4 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein Succ_DH_flav_C PF02910.15 ETO11002.1 - 0.085 12.7 0.6 0.26 11.1 0.0 2.0 3 0 0 3 3 3 0 Fumarate reductase flavoprotein C-term Fmp27_SW PF10305.4 ETO11002.1 - 0.092 13.1 0.1 0.31 11.4 0.0 1.9 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF3807 PF12720.2 ETO11003.1 - 0.43 10.7 10.9 0.5 10.5 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) AAA_11 PF13086.1 ETO11003.1 - 0.71 9.3 8.7 0.78 9.2 6.0 1.1 1 0 0 1 1 1 0 AAA domain DUF4220 PF13968.1 ETO11003.1 - 1.2 8.1 6.3 1.3 8.0 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) YqfQ PF14181.1 ETO11003.1 - 1.5 8.8 13.5 2.4 8.1 9.4 1.4 1 0 0 1 1 1 0 YqfQ-like protein DDHD PF02862.12 ETO11003.1 - 4.2 7.1 9.0 5.6 6.6 6.3 1.2 1 0 0 1 1 1 0 DDHD domain Neur_chan_memb PF02932.11 ETO11003.1 - 6.9 6.4 6.3 7.8 6.3 4.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GAGA_bind PF06217.7 ETO11003.1 - 7 6.5 19.4 9.4 6.1 13.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Tantalus PF15386.1 ETO11004.1 - 0.048 13.4 0.1 0.13 12.0 0.1 1.7 1 0 0 1 1 1 0 Drosophila Tantalus-like zf-LITAF-like PF10601.4 ETO11004.1 - 0.41 10.5 6.9 1.1 9.1 4.8 1.7 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain RAI1 PF08652.6 ETO11006.1 - 1.1e-05 25.0 0.6 0.00021 21.0 0.0 2.3 2 0 0 2 2 2 2 RAI1 like PD-(D/E)XK nuclease Tom37_C PF11801.3 ETO11007.1 - 0.089 12.6 0.6 0.15 11.9 0.4 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain U-box PF04564.10 ETO11008.1 - 9e-12 44.7 0.0 3e-11 43.0 0.0 1.9 1 1 0 1 1 1 1 U-box domain Kelch_6 PF13964.1 ETO11009.1 - 3.4e-07 30.1 6.8 0.0017 18.4 0.1 4.4 4 1 1 5 5 5 2 Kelch motif Kelch_3 PF13415.1 ETO11009.1 - 0.00028 20.9 0.2 0.018 15.2 0.0 3.8 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO11009.1 - 0.00088 18.9 4.5 0.21 11.3 0.2 3.6 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO11009.1 - 0.0073 16.2 5.6 0.089 12.7 0.3 4.2 6 0 0 6 6 6 1 Kelch motif Kelch_2 PF07646.10 ETO11009.1 - 0.0083 15.8 4.6 0.067 12.9 0.3 3.5 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 ETO11009.1 - 0.027 14.0 0.3 0.027 14.0 0.2 3.5 4 0 0 4 4 4 0 Kelch motif DUF3979 PF13141.1 ETO11010.1 - 0.096 12.5 4.4 0.088 12.7 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3979) Na_Ca_ex PF01699.19 ETO11011.1 - 1.8e-22 79.4 13.1 1.8e-22 79.4 9.1 1.5 2 0 0 2 2 2 1 Sodium/calcium exchanger protein BSP_II PF05432.6 ETO11011.1 - 0.096 11.9 7.5 0.14 11.4 5.2 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Macoilin PF09726.4 ETO11011.1 - 3 5.9 6.8 4.1 5.5 4.7 1.1 1 0 0 1 1 1 0 Transmembrane protein TRAP_alpha PF03896.11 ETO11011.1 - 4 6.3 7.3 13 4.6 5.1 1.8 1 1 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF1774 PF08611.5 ETO11012.1 - 0.088 12.9 8.1 1.6 8.9 0.1 2.3 2 1 0 2 2 2 0 Fungal protein of unknown function (DUF1774) DUF1044 PF06296.7 ETO11013.1 - 0.014 15.2 0.6 0.023 14.5 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1044) DIX PF00778.12 ETO11013.1 - 0.059 13.0 0.5 0.12 12.1 0.3 1.6 1 1 0 1 1 1 0 DIX domain Activin_recp PF01064.18 ETO11014.1 - 1.3 9.7 7.4 0.5 11.0 0.6 2.3 2 0 0 2 2 2 0 Activin types I and II receptor domain WD40 PF00400.27 ETO11015.1 - 2.8e-39 131.5 19.9 4.2e-11 42.2 0.2 5.7 5 1 1 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO11015.1 - 7.9e-08 30.8 1.9 0.0012 17.0 0.2 3.2 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Serpin PF00079.15 ETO11016.1 - 0.0087 15.2 0.1 0.016 14.3 0.1 1.6 1 1 0 1 1 1 1 Serpin (serine protease inhibitor) BatD PF13584.1 ETO11016.1 - 0.012 14.2 0.5 0.017 13.7 0.4 1.2 1 0 0 1 1 1 0 Oxygen tolerance ABC2_membrane_3 PF12698.2 ETO11016.1 - 0.018 14.0 1.4 0.024 13.7 0.9 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein ETRAMP PF09716.5 ETO11016.1 - 0.26 11.2 7.1 0.3 11.0 0.6 2.5 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) FBPase PF00316.15 ETO11017.1 - 0.027 13.3 0.0 0.031 13.0 0.0 1.1 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase FAD_binding_4 PF01565.18 ETO11017.1 - 0.063 12.7 0.0 0.099 12.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HTH_40 PF14493.1 ETO11018.1 - 0.059 13.5 1.8 0.14 12.4 0.2 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain HSP70 PF00012.15 ETO11020.1 - 0.0064 14.4 0.0 0.011 13.6 0.0 1.4 1 1 0 1 1 1 1 Hsp70 protein Hydantoinase_A PF01968.13 ETO11020.1 - 0.13 11.3 0.0 0.34 9.9 0.0 1.6 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase WD40 PF00400.27 ETO11021.1 - 3.9e-60 197.7 25.0 1.9e-12 46.5 0.1 7.0 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO11021.1 - 3.3e-12 45.3 7.8 0.0004 18.6 0.1 5.4 1 1 4 6 6 6 5 Nucleoporin Nup120/160 Cu-oxidase_2 PF07731.9 ETO11021.1 - 0.06 12.8 1.6 0.12 11.8 0.4 2.2 2 1 0 2 2 2 0 Multicopper oxidase DUF4024 PF13216.1 ETO11021.1 - 3.2 7.6 6.9 5.4 6.9 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4024) HEAT_2 PF13646.1 ETO11022.1 - 2.6e-17 62.8 6.4 2.8e-05 24.3 0.1 6.8 4 2 3 7 7 7 4 HEAT repeats DUF294 PF03445.8 ETO11022.1 - 1.6e-07 31.0 0.3 2.5e-05 23.8 0.0 3.1 2 0 0 2 2 2 1 Putative nucleotidyltransferase DUF294 DUF2435 PF10363.4 ETO11022.1 - 0.00017 21.4 5.6 0.017 15.0 0.1 5.0 3 3 2 5 5 5 1 Protein of unknown function (DUF2435) DUF294_C PF10335.4 ETO11022.1 - 0.00027 20.5 0.1 0.00094 18.8 0.0 2.0 1 0 0 1 1 1 1 Putative nucleotidyltransferase substrate binding domain LRR_6 PF13516.1 ETO11022.1 - 0.0034 17.2 2.3 1.7 8.9 0.0 4.1 3 0 0 3 3 3 1 Leucine Rich repeat HEAT PF02985.17 ETO11022.1 - 0.0047 16.8 8.3 5.9 7.2 0.1 6.8 8 0 0 8 8 8 1 HEAT repeat HEAT_EZ PF13513.1 ETO11022.1 - 0.18 12.3 1.9 1.4e+02 3.1 0.0 4.9 5 0 0 5 5 5 0 HEAT-like repeat Ank_2 PF12796.2 ETO11023.1 - 4.4e-21 75.0 5.8 1e-09 38.5 0.2 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO11023.1 - 2e-12 47.2 2.0 5.4e-06 26.7 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO11023.1 - 1.8e-11 43.8 0.6 1.6e-07 31.3 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO11023.1 - 2.3e-10 39.6 0.1 4.8e-05 23.2 0.0 4.3 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.25 ETO11023.1 - 1.5e-08 34.0 0.0 1.9e-06 27.3 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat DUF4142 PF13628.1 ETO11024.1 - 0.0042 17.1 0.9 0.0053 16.7 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4142) RNA_pol_Rpb4 PF03874.11 ETO11024.1 - 0.089 12.8 2.4 0.15 12.0 1.6 1.6 1 1 0 1 1 1 0 RNA polymerase Rpb4 COX5A PF02284.11 ETO11024.1 - 0.86 9.5 4.2 2.6 8.0 0.7 2.4 2 1 0 2 2 2 0 Cytochrome c oxidase subunit Va WD40 PF00400.27 ETO11025.1 - 5.3e-17 60.9 8.0 2.5e-09 36.6 0.5 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO11025.1 - 0.00035 18.8 0.4 0.00081 17.6 0.1 1.7 1 1 1 2 2 2 1 Nucleoporin Nup120/160 TPR_11 PF13414.1 ETO11026.1 - 1.6e-21 75.7 5.8 9.3e-17 60.4 0.3 2.6 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 ETO11026.1 - 1.7e-18 65.3 7.4 2e-05 23.9 0.3 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat RPAP3_C PF13877.1 ETO11026.1 - 3.3e-14 52.6 2.5 1.4e-12 47.4 0.9 3.4 2 1 0 2 2 2 1 Potential Monad-binding region of RPAP3 TPR_2 PF07719.12 ETO11026.1 - 5.6e-14 50.8 4.8 0.00024 20.7 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO11026.1 - 1.9e-05 24.4 0.8 0.00022 21.1 0.0 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO11026.1 - 0.00029 20.3 12.1 0.26 11.1 1.4 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO11026.1 - 0.00048 20.4 0.7 0.0031 17.8 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO11026.1 - 0.0057 17.2 0.5 0.17 12.5 0.0 2.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO11026.1 - 0.0082 16.6 0.0 1.8 9.3 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETO11026.1 - 0.0094 15.7 0.0 1.3 8.9 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO11026.1 - 0.015 15.2 2.4 13 5.8 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 ETO11026.1 - 0.068 13.3 4.1 0.12 12.4 0.7 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DnaJ PF00226.26 ETO11027.1 - 3.5e-31 106.7 4.3 3.5e-31 106.7 3.0 2.2 2 1 0 2 2 2 1 DnaJ domain Zip PF02535.17 ETO11027.1 - 0.12 11.3 1.1 0.18 10.7 0.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2201_N PF13203.1 ETO11027.1 - 1.8 7.6 12.2 2.8 7.0 8.5 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain adh_short PF00106.20 ETO11028.1 - 5.8e-15 55.5 0.0 7.1e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 ETO11028.1 - 8.2e-10 38.0 1.7 1e-09 37.7 1.2 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 ETO11028.1 - 6.7e-08 32.3 0.0 9.2e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 ETO11028.1 - 0.0016 17.5 0.3 0.0019 17.2 0.2 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 ETO11028.1 - 0.0065 15.9 0.1 0.0087 15.5 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Corona_NS3b PF03053.9 ETO11028.1 - 0.04 13.4 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 ORF3b coronavirus protein TehB PF03848.9 ETO11028.1 - 0.064 12.4 0.7 0.11 11.6 0.3 1.4 1 1 0 1 1 1 0 Tellurite resistance protein TehB GARS_N PF02844.10 ETO11028.1 - 0.26 11.7 1.5 5.1 7.6 1.1 2.2 1 1 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain SHP PF03579.8 ETO11028.1 - 0.27 10.5 1.6 0.76 9.1 1.1 1.7 1 0 0 1 1 1 0 Small hydrophobic protein WD40 PF00400.27 ETO11029.1 - 1.1e-12 47.2 0.1 5.2e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO11029.1 - 0.06 11.4 0.1 0.19 9.8 0.1 1.8 1 1 0 1 1 1 0 Nucleoporin Nup120/160 CLASP_N PF12348.3 ETO11030.1 - 3e-10 39.8 3.6 3.5e-10 39.6 2.5 1.1 1 0 0 1 1 1 1 CLASP N terminal HATPase_c_3 PF13589.1 ETO11032.1 - 4.4e-08 32.8 1.5 4.9e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 ETO11032.1 - 6.5e-08 32.2 0.0 1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2360 PF10152.4 ETO11032.1 - 0.059 13.6 5.7 0.09 13.0 3.9 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) ETRAMP PF09716.5 ETO11032.1 - 0.078 12.9 2.1 0.51 10.3 0.2 2.4 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) AIF-MLS PF14962.1 ETO11032.1 - 0.14 11.8 6.1 0.18 11.4 4.2 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Bac_small_YrzI PF09501.5 ETO11032.1 - 0.45 10.4 5.6 0.64 9.9 1.4 2.8 2 1 1 3 3 3 0 Probable sporulation protein (Bac_small_yrzI) ETRAMP PF09716.5 ETO11033.1 - 0.055 13.4 0.9 0.92 9.5 0.0 2.3 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF869 PF05911.6 ETO11034.1 - 0.0033 15.7 10.2 0.0041 15.4 7.1 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) SGS PF05002.10 ETO11035.1 - 1.8e-23 82.1 4.7 1.8e-23 82.1 3.3 1.9 2 0 0 2 2 2 1 SGS domain CS PF04969.11 ETO11035.1 - 2.9e-08 34.1 1.8 6.1e-08 33.0 1.2 1.6 1 0 0 1 1 1 1 CS domain PSDC PF12588.3 ETO11035.1 - 0.058 13.0 0.8 0.42 10.2 0.0 2.2 2 0 0 2 2 2 0 Phophatidylserine decarboxylase DUF2057 PF09829.4 ETO11035.1 - 2 8.0 10.2 3.5 7.2 6.4 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) Clathrin_H_link PF13838.1 ETO11036.1 - 5e-10 39.1 0.7 8.6e-10 38.3 0.5 1.4 1 0 0 1 1 1 1 Clathrin-H-link Kelch_6 PF13964.1 ETO11037.1 - 8.8e-06 25.6 2.6 0.15 12.3 0.1 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO11037.1 - 0.02 14.4 2.9 0.97 9.0 0.2 3.6 3 0 0 3 3 3 0 Kelch motif WD40 PF00400.27 ETO11038.1 - 2.5e-08 33.5 1.9 1.4e-06 27.9 0.0 3.0 2 1 0 2 2 2 2 WD domain, G-beta repeat FOP_dimer PF09398.5 ETO11038.1 - 0.036 14.0 0.1 0.36 10.8 0.0 2.2 1 1 1 2 2 2 0 FOP N terminal dimerisation domain Tctex-1 PF03645.8 ETO11039.1 - 3.6e-21 74.8 2.4 3.6e-21 74.8 1.6 2.4 2 0 0 2 2 2 1 Tctex-1 family RNase_E_G PF10150.4 ETO11039.1 - 0.0087 15.3 2.4 0.018 14.2 0.7 2.0 2 0 0 2 2 2 1 Ribonuclease E/G family Ribosomal_S26e PF01283.14 ETO11039.1 - 0.026 14.7 2.8 5.6 7.2 0.0 2.8 3 0 0 3 3 3 0 Ribosomal protein S26e DDA1 PF10172.4 ETO11039.1 - 0.55 10.0 4.5 1.9 8.3 0.0 2.5 2 0 0 2 2 2 0 Det1 complexing ubiquitin ligase DUF1618 PF07762.9 ETO11039.1 - 0.69 10.1 3.4 2 8.5 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1618) AAA_5 PF07728.9 ETO11040.1 - 1.1e-19 70.5 0.1 9.5e-09 35.0 0.0 2.6 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETO11040.1 - 7.3e-06 26.1 1.2 0.0015 18.6 0.0 2.8 2 1 0 3 3 3 1 AAA domain ABC_tran PF00005.22 ETO11040.1 - 7.3e-06 26.3 0.7 0.00018 21.8 0.0 2.7 3 0 0 3 3 2 1 ABC transporter RuvB_N PF05496.7 ETO11040.1 - 1e-05 24.7 0.1 0.012 14.7 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus Sigma54_activ_2 PF14532.1 ETO11040.1 - 2.1e-05 24.5 0.0 6.1e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.24 ETO11040.1 - 2.7e-05 24.3 0.0 0.0014 18.8 0.0 2.4 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETO11040.1 - 0.00024 21.1 0.0 0.00059 19.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.21 ETO11040.1 - 0.00071 19.0 0.2 0.0049 16.3 0.0 2.4 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_30 PF13604.1 ETO11040.1 - 0.00086 18.9 0.2 0.24 10.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ETO11040.1 - 0.001 19.9 0.0 0.0027 18.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 ETO11040.1 - 0.0015 18.5 0.0 0.024 14.6 0.0 2.5 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.1 ETO11040.1 - 0.002 18.0 0.1 0.082 12.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 ETO11040.1 - 0.0025 17.6 0.1 0.0062 16.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 ETO11040.1 - 0.0034 17.3 0.1 2.3 8.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 ETO11040.1 - 0.0044 17.3 0.1 0.021 15.0 0.0 2.2 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 ETO11040.1 - 0.0044 16.6 4.1 0.068 12.8 0.3 3.6 3 1 0 3 3 3 1 NACHT domain AAA_29 PF13555.1 ETO11040.1 - 0.0049 16.3 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF815 PF05673.8 ETO11040.1 - 0.0065 15.4 0.3 0.035 13.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) UPF0079 PF02367.12 ETO11040.1 - 0.0066 16.0 0.0 0.02 14.5 0.0 1.8 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 ETO11040.1 - 0.0083 15.8 0.0 0.046 13.4 0.0 2.1 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 ETO11040.1 - 0.0093 15.6 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain DUF258 PF03193.11 ETO11040.1 - 0.01 15.0 0.0 0.037 13.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 ETO11040.1 - 0.014 15.7 0.0 0.026 14.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 ETO11040.1 - 0.014 14.8 0.0 0.037 13.4 0.0 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain T2SE PF00437.15 ETO11040.1 - 0.021 13.7 0.0 0.037 12.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Mg_chelatase PF01078.16 ETO11040.1 - 0.03 13.4 0.0 0.24 10.5 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 ETO11040.1 - 0.032 13.3 0.0 0.061 12.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PduV-EutP PF10662.4 ETO11040.1 - 0.033 13.6 0.0 0.075 12.5 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 ETO11040.1 - 0.034 13.5 0.4 0.17 11.2 0.1 2.1 1 1 1 2 2 2 0 AAA domain PhoH PF02562.11 ETO11040.1 - 0.04 13.1 0.0 0.076 12.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein SMC_N PF02463.14 ETO11040.1 - 0.051 12.7 0.1 5.2 6.2 0.1 2.5 2 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain NTPase_1 PF03266.10 ETO11040.1 - 0.053 13.2 0.5 3 7.5 0.0 2.7 2 1 0 2 2 2 0 NTPase AAA_3 PF07726.6 ETO11040.1 - 0.058 13.0 0.8 1.5 8.3 0.0 2.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 ETO11040.1 - 0.069 13.1 0.1 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 ETO11040.1 - 0.083 12.7 0.1 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DEAD PF00270.24 ETO11040.1 - 0.092 12.2 0.1 0.17 11.3 0.1 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase Miro PF08477.8 ETO11040.1 - 0.095 13.2 0.0 0.34 11.4 0.0 2.0 1 1 0 1 1 1 0 Miro-like protein MMR_HSR1 PF01926.18 ETO11040.1 - 0.12 12.3 0.2 0.85 9.6 0.1 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase IstB_IS21 PF01695.12 ETO11040.1 - 0.16 11.3 1.1 0.22 10.9 0.1 2.0 2 1 0 2 2 1 0 IstB-like ATP binding protein DNA_pack_N PF02500.10 ETO11041.1 - 0.011 15.2 0.2 0.015 14.8 0.1 1.1 1 0 0 1 1 1 0 Probable DNA packing protein, N-terminus DUF2852 PF11014.3 ETO11041.1 - 0.012 15.5 1.0 0.017 15.0 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) WD40 PF00400.27 ETO11042.1 - 1.3e-60 199.1 33.7 3.5e-12 45.6 0.1 7.4 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO11042.1 - 1.1e-11 43.6 5.2 0.12 10.4 0.0 5.7 1 1 3 5 5 5 5 Nucleoporin Nup120/160 WD40 PF00400.27 ETO11043.1 - 1e-166 535.6 52.2 5.5e-12 45.0 0.1 16.3 16 0 0 16 16 16 16 WD domain, G-beta repeat Nup160 PF11715.3 ETO11043.1 - 9.2e-19 66.9 31.5 0.064 11.3 0.2 13.2 1 1 10 11 11 11 10 Nucleoporin Nup120/160 Str_synth PF03088.11 ETO11043.1 - 6.8e-07 29.2 1.9 15 5.6 0.0 7.4 7 1 1 8 8 8 0 Strictosidine synthase Cytochrom_D1 PF02239.11 ETO11043.1 - 8.6e-07 27.5 15.1 0.057 11.7 0.0 5.8 2 1 3 6 6 6 4 Cytochrome D1 heme domain DUF1258 PF06869.7 ETO11043.1 - 6.5e-05 22.1 8.5 0.18 10.8 0.1 5.9 5 1 2 7 7 7 2 Protein of unknown function (DUF1258) Pentapeptide PF00805.17 ETO11043.1 - 0.01 15.0 0.0 0.023 13.9 0.0 1.5 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) NACHT PF05729.7 ETO11043.1 - 0.018 14.6 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Resistin PF06954.6 ETO11043.1 - 0.061 13.5 0.9 30 4.9 0.0 4.8 4 1 1 5 5 5 0 Resistin PLD_C PF12357.3 ETO11043.1 - 0.23 11.0 2.5 35 4.0 0.0 5.6 5 2 3 8 8 8 0 Phospholipase D C terminal PD40 PF07676.7 ETO11043.1 - 8.1 6.2 18.7 48 3.7 0.1 6.9 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat Peptidase_M20 PF01546.23 ETO11047.1 - 2.7e-16 59.6 0.0 3.6e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF3789 PF12664.2 ETO11048.1 - 1.8 7.9 7.0 1.7 8.0 1.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3789) Corona_6B_7B PF03262.8 ETO11049.1 - 0.051 12.8 0.1 0.06 12.5 0.1 1.2 1 0 0 1 1 1 0 Coronavirus 6B/7B protein DUF4234 PF14018.1 ETO11049.1 - 1.5 8.6 3.7 10 5.9 2.6 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) TPR_12 PF13424.1 ETO11050.1 - 6.9e-67 221.3 20.4 8.8e-19 67.2 1.8 6.8 5 2 2 7 7 6 6 Tetratricopeptide repeat TPR_11 PF13414.1 ETO11050.1 - 1.9e-38 129.9 21.7 1e-09 37.8 0.2 6.2 5 1 0 5 5 5 5 TPR repeat TPR_1 PF00515.23 ETO11050.1 - 6.3e-38 126.8 39.0 2.2e-07 30.1 0.6 8.3 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_10 PF13374.1 ETO11050.1 - 2.7e-35 119.2 0.0 1.1e-05 25.1 0.0 8.2 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_7 PF13176.1 ETO11050.1 - 1.5e-27 93.1 17.5 0.00023 20.7 0.1 8.7 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.12 ETO11050.1 - 1.2e-26 90.3 35.3 0.00012 21.6 0.2 8.4 8 0 0 8 8 7 7 Tetratricopeptide repeat TPR_8 PF13181.1 ETO11050.1 - 1.2e-20 71.6 47.2 3.6e-05 23.2 1.0 9.4 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_16 PF13432.1 ETO11050.1 - 4.2e-12 46.3 5.3 0.0055 17.3 0.0 6.2 4 2 1 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 ETO11050.1 - 2e-10 40.6 22.7 5.6e-05 23.1 0.9 5.2 4 1 1 5 5 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 ETO11050.1 - 7.4e-09 35.4 2.6 33 5.4 0.0 7.5 7 1 0 7 7 7 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO11050.1 - 1.6e-08 33.6 2.6 0.12 11.6 0.0 6.5 7 0 0 7 7 7 2 SHNi-TPR TPR_6 PF13174.1 ETO11050.1 - 1.5e-06 28.2 15.1 5.7 7.6 0.1 8.6 9 0 0 9 9 9 1 Tetratricopeptide repeat MIT PF04212.13 ETO11050.1 - 3.7e-06 26.7 21.6 0.99 9.3 0.4 7.8 6 1 1 7 7 7 3 MIT (microtubule interacting and transport) domain TPR_17 PF13431.1 ETO11050.1 - 2e-05 24.4 13.6 2.6 8.4 0.3 7.5 7 2 1 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO11050.1 - 0.00023 21.4 7.8 0.56 10.5 0.2 4.5 4 0 0 4 4 3 2 Tetratricopeptide repeat AAA_22 PF13401.1 ETO11051.1 - 0.031 14.4 0.1 0.43 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 ETO11051.1 - 0.035 14.0 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain T2SE PF00437.15 ETO11051.1 - 0.07 12.0 0.0 6.9 5.4 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 ETO11051.1 - 0.071 12.1 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin TFIIA PF03153.8 ETO11052.1 - 0.017 15.0 27.7 0.024 14.5 19.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2151 PF10221.4 ETO11052.1 - 0.032 12.4 23.5 0.044 11.9 16.3 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator NOA36 PF06524.7 ETO11052.1 - 0.18 11.0 23.2 0.33 10.1 16.1 1.5 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 ETO11052.1 - 0.32 8.8 34.9 0.47 8.3 24.2 1.2 1 0 0 1 1 1 0 Nop14-like family SPX PF03105.14 ETO11052.1 - 5.1 6.7 39.4 8.2 6.1 27.3 1.4 1 1 0 1 1 1 0 SPX domain ABC_sub_bind PF04392.7 ETO11053.1 - 1e-31 110.0 1.2 1.1e-24 86.8 0.1 2.0 1 1 1 2 2 2 2 ABC transporter substrate binding protein Peripla_BP_6 PF13458.1 ETO11053.1 - 0.01 15.2 0.0 0.014 14.8 0.0 1.2 1 1 0 1 1 1 0 Periplasmic binding protein LpxC PF03331.8 ETO11054.1 - 2.9e-58 197.0 0.2 3.3e-58 196.8 0.2 1.0 1 0 0 1 1 1 1 UDP-3-O-acyl N-acetylglycosamine deacetylase Glyco_trans_4_2 PF13477.1 ETO11055.1 - 7.4e-16 58.2 2.5 1e-15 57.7 1.7 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glycos_transf_1 PF00534.15 ETO11055.1 - 0.0015 17.9 0.1 0.0042 16.5 0.0 1.8 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_28 PF03033.15 ETO11055.1 - 0.029 14.1 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Epimerase PF01370.16 ETO11056.1 - 3e-54 183.9 0.1 3.6e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETO11056.1 - 2.2e-20 72.5 0.1 2.7e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 ETO11056.1 - 5e-17 61.7 0.2 5.2e-16 58.4 0.1 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 ETO11056.1 - 7.4e-13 48.0 0.0 1e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 ETO11056.1 - 6.3e-12 44.9 0.3 2.2e-07 30.0 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 ETO11056.1 - 4.2e-09 36.6 0.0 6.3e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 ETO11056.1 - 3e-06 27.2 0.0 6.1e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 ETO11056.1 - 4.4e-05 22.8 0.1 0.0001 21.6 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family KR PF08659.5 ETO11056.1 - 0.00054 19.6 0.1 0.0055 16.3 0.1 2.4 1 1 0 1 1 1 1 KR domain Rad9_Rad53_bind PF08605.5 ETO11057.1 - 0.0075 16.0 1.0 1.9 8.2 0.0 2.3 2 0 0 2 2 2 2 Fungal Rad9-like Rad53-binding PUB PF09409.5 ETO11058.1 - 0.0063 16.2 0.0 0.025 14.3 0.0 2.1 1 1 0 1 1 1 1 PUB domain SNARE PF05739.14 ETO11060.1 - 7.9e-07 28.6 0.8 9e-07 28.4 0.5 1.1 1 0 0 1 1 1 1 SNARE domain Sec20 PF03908.8 ETO11060.1 - 0.0059 16.2 0.2 0.0074 15.9 0.2 1.3 1 1 0 1 1 1 1 Sec20 APG17 PF04108.7 ETO11060.1 - 0.076 11.7 0.1 0.088 11.5 0.1 1.0 1 0 0 1 1 1 0 Autophagy protein Apg17 HJURP_C PF12347.3 ETO11061.1 - 0.023 14.2 1.0 7.9 6.1 0.2 3.0 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat DUF3166 PF11365.3 ETO11061.1 - 0.044 14.2 13.8 0.21 12.0 1.2 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3166) IncA PF04156.9 ETO11061.1 - 0.82 9.2 28.3 0.2 11.1 1.7 2.9 2 1 0 2 2 2 0 IncA protein Presenilin PF01080.12 ETO11061.1 - 1.4 7.6 6.1 3.5 6.3 0.1 2.2 2 0 0 2 2 2 0 Presenilin Helicase_C PF00271.26 ETO11062.1 - 9.6e-18 63.8 0.1 2.1e-17 62.7 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETO11062.1 - 1.8e-09 37.2 1.9 2.7e-09 36.7 0.4 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C_2 PF13307.1 ETO11062.1 - 0.32 10.9 1.5 3.2 7.6 0.0 2.1 2 0 0 2 2 2 0 Helicase C-terminal domain PMSR PF01625.16 ETO11063.1 - 0.044 13.6 0.0 0.079 12.8 0.0 1.3 1 0 0 1 1 1 0 Peptide methionine sulfoxide reductase TPR_11 PF13414.1 ETO11064.1 - 4.6e-27 93.4 27.6 2.2e-11 43.2 4.2 5.3 3 1 3 6 6 6 4 TPR repeat TPR_17 PF13431.1 ETO11064.1 - 1.2e-14 53.2 22.2 0.00036 20.4 1.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO11064.1 - 1.6e-14 54.0 14.9 8.9e-06 26.2 1.9 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO11064.1 - 3.5e-12 45.2 28.6 0.02 14.7 0.3 7.0 6 1 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.23 ETO11064.1 - 2.3e-11 42.7 28.2 0.0027 17.2 1.9 6.4 4 2 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO11064.1 - 1.4e-10 40.7 9.1 0.12 13.1 0.0 6.0 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 ETO11064.1 - 7.8e-10 38.9 16.2 0.00078 19.7 2.1 4.9 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 ETO11064.1 - 1.1e-09 38.0 28.0 6.6e-06 25.9 5.2 5.0 3 1 3 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO11064.1 - 3.9e-08 32.5 23.7 0.021 14.5 2.0 5.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 ETO11064.1 - 0.0027 17.5 5.2 0.017 14.9 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO11064.1 - 0.015 15.6 10.3 25 5.6 0.2 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETO11064.1 - 0.11 12.3 13.3 15 5.6 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO11064.1 - 1.5 8.7 10.4 1.2 9.0 0.1 4.3 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Couple_hipA PF13657.1 ETO11065.1 - 0.09 13.0 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 HipA N-terminal domain DUF2280 PF10045.4 ETO11067.1 - 0.065 13.1 0.2 0.08 12.8 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2280) BLYB PF05289.6 ETO11067.1 - 1.2 8.9 6.0 0.26 11.0 1.9 1.5 2 0 0 2 2 2 0 Borrelia hemolysin accessory protein RRF_GI PF12614.3 ETO11068.1 - 0.092 12.5 4.0 0.15 11.8 0.9 2.4 2 0 0 2 2 2 0 Ribosome recycling factor Helicase_C_2 PF13307.1 ETO11068.1 - 0.15 12.0 0.9 3 7.7 0.2 2.3 2 0 0 2 2 2 0 Helicase C-terminal domain Kelch_5 PF13854.1 ETO11069.1 - 0.0043 16.9 0.0 4.3 7.4 0.0 2.3 2 0 0 2 2 2 2 Kelch motif DUF4563 PF15124.1 ETO11069.1 - 0.031 13.8 1.6 0.25 10.9 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4563) PTEN_C2 PF10409.4 ETO11069.1 - 0.09 12.5 0.8 0.39 10.4 0.6 2.0 1 1 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein Kelch_2 PF07646.10 ETO11069.1 - 0.092 12.5 0.0 4.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Kelch motif Kelch_6 PF13964.1 ETO11069.1 - 0.11 12.7 0.0 1 9.6 0.0 2.2 2 0 0 2 2 2 0 Kelch motif MRP-S27 PF10037.4 ETO11069.1 - 0.58 9.0 10.2 0.75 8.6 7.1 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DUF3926 PF13080.1 ETO11069.1 - 1.2 8.7 5.9 0.77 9.3 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3926) DUF1054 PF06335.7 ETO11069.1 - 2.3 7.8 6.6 3.9 7.0 2.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1054) Herpes_US9 PF06072.6 ETO11070.1 - 0.37 10.6 2.9 0.87 9.4 2.0 1.6 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Kelch_6 PF13964.1 ETO11071.1 - 1.2e-08 34.7 3.8 0.00062 19.8 0.3 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 ETO11071.1 - 2.1e-08 33.5 5.7 0.00053 19.4 0.4 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO11071.1 - 5.5e-08 32.4 2.0 0.0031 17.2 0.2 3.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO11071.1 - 5e-06 26.0 2.6 0.00088 18.9 0.3 3.8 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 ETO11071.1 - 5e-05 23.3 0.5 0.0075 16.4 0.0 3.9 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO11071.1 - 0.093 12.7 3.9 7.5 6.6 0.2 4.7 6 0 0 6 6 6 0 Kelch motif RasGEF_N PF00618.15 ETO11072.1 - 8.8e-05 22.5 5.1 0.0002 21.4 1.2 2.9 2 1 1 3 3 3 1 RasGEF N-terminal motif DUF3677 PF12432.3 ETO11072.1 - 0.01 16.2 5.1 0.19 12.1 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3677) APC10 PF03256.11 ETO11072.1 - 0.033 13.7 0.6 0.14 11.7 0.1 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex, subunit 10 (APC10) PPR PF01535.15 ETO11073.1 - 2.1e-17 61.7 5.4 7.7e-05 22.4 0.0 5.0 4 0 0 4 4 4 4 PPR repeat PPR_2 PF13041.1 ETO11073.1 - 3.8e-16 58.7 15.9 2.3e-09 37.0 0.2 5.3 3 1 3 6 6 6 4 PPR repeat family PPR_3 PF13812.1 ETO11073.1 - 2.3e-14 52.3 0.0 0.0042 17.2 0.0 5.1 5 0 0 5 5 5 3 Pentatricopeptide repeat domain PPR_1 PF12854.2 ETO11073.1 - 1.9e-09 36.7 4.3 7.4e-05 22.1 0.0 4.3 5 0 0 5 5 5 3 PPR repeat CAP_N PF01213.14 ETO11074.1 - 0.00047 19.5 4.1 0.00047 19.5 2.9 2.5 3 0 0 3 3 3 1 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 ETO11074.1 - 0.003 16.9 10.1 0.003 16.9 7.0 2.6 2 0 0 2 2 2 1 Mitochondrial fission regulator 4HBT_3 PF13622.1 ETO11074.1 - 0.0061 16.3 0.9 0.0061 16.3 0.7 1.8 2 0 0 2 2 2 1 Thioesterase-like superfamily Nucleoside_tran PF01733.13 ETO11074.1 - 0.15 11.1 1.4 0.39 9.8 1.0 1.7 1 0 0 1 1 1 0 Nucleoside transporter Kinetocho_Slk19 PF12709.2 ETO11074.1 - 4.2 7.5 16.9 0.15 12.1 3.2 3.4 3 0 0 3 3 3 0 Central kinetochore-associated WD40 PF00400.27 ETO11075.1 - 2.6e-22 77.7 25.0 1.3e-08 34.3 0.7 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO11075.1 - 0.00017 20.0 0.3 0.29 9.4 0.0 2.2 1 1 2 3 3 3 3 Cytochrome D1 heme domain HPS3_N PF14761.1 ETO11075.1 - 0.0089 15.4 0.1 0.032 13.6 0.0 1.8 1 1 1 2 2 2 1 Hermansky-Pudlak syndrome 3 CPSF_A PF03178.10 ETO11075.1 - 0.018 14.1 1.3 0.088 11.8 0.5 1.9 1 1 1 2 2 2 0 CPSF A subunit region Coatomer_WDAD PF04053.9 ETO11075.1 - 0.033 12.9 3.7 0.12 11.1 1.4 2.4 1 1 1 2 2 2 0 Coatomer WD associated region DUF4116 PF13475.1 ETO11075.1 - 0.036 13.5 0.2 1.9 8.0 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4116) VGCC_alpha2 PF08473.6 ETO11075.1 - 0.041 13.6 0.4 0.085 12.6 0.3 1.5 1 0 0 1 1 1 0 Neuronal voltage-dependent calcium channel alpha 2acd Big_3 PF07523.7 ETO11075.1 - 0.3 11.2 2.0 0.63 10.1 0.0 2.4 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) N6_Mtase PF02384.11 ETO11076.1 - 0.066 12.2 0.1 0.074 12.1 0.1 1.1 1 0 0 1 1 1 0 N-6 DNA Methylase WD40 PF00400.27 ETO11077.1 - 7e-11 41.5 0.2 6.1e-10 38.5 0.1 2.2 2 1 0 2 2 2 1 WD domain, G-beta repeat HAD PF12710.2 ETO11077.1 - 0.13 12.3 0.1 0.2 11.7 0.0 1.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase WD40 PF00400.27 ETO11078.1 - 1.9e-21 75.1 11.6 4.8e-11 42.1 1.3 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO11078.1 - 1.2e-05 23.6 1.1 0.0013 16.9 0.2 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF1914 PF08932.5 ETO11078.1 - 1.3 9.0 4.0 6.7 6.7 0.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1914) Kelch_6 PF13964.1 ETO11079.1 - 1.9e-09 37.3 3.7 0.0019 18.3 0.1 4.6 3 1 1 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO11079.1 - 2e-08 33.8 1.1 0.0044 16.7 0.0 3.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO11079.1 - 8.3e-08 31.7 5.0 0.0052 16.5 0.2 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 ETO11079.1 - 1.5e-06 27.6 8.3 0.00072 19.0 0.1 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO11079.1 - 0.00081 19.2 4.2 1.8 8.6 0.1 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 ETO11079.1 - 0.0028 17.7 1.8 0.056 13.6 0.0 3.5 4 0 0 4 4 4 1 Galactose oxidase, central domain NACHT PF05729.7 ETO11080.1 - 6.8e-05 22.5 0.2 0.00043 19.9 0.1 2.2 1 1 0 1 1 1 1 NACHT domain NifQ PF04891.7 ETO11080.1 - 1.5 8.9 3.9 11 6.1 0.2 2.9 3 0 0 3 3 3 0 NifQ NACHT PF05729.7 ETO11081.1 - 1.5e-09 37.6 0.0 2.8e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO11081.1 - 1.4e-05 25.4 0.1 1.4e-05 25.4 0.0 3.6 3 1 1 4 4 4 1 AAA domain AAA_22 PF13401.1 ETO11081.1 - 0.00033 20.7 0.0 0.0015 18.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ETO11081.1 - 0.00092 20.0 2.3 0.008 16.9 0.0 3.4 4 0 0 4 4 4 1 AAA domain DUF258 PF03193.11 ETO11081.1 - 0.023 13.9 0.0 0.056 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Ras PF00071.17 ETO11083.1 - 0.015 14.6 0.3 0.036 13.4 0.0 1.7 2 0 0 2 2 2 0 Ras family GTP_EFTU PF00009.22 ETO11084.1 - 5e-32 110.8 0.0 7.6e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 ETO11084.1 - 3.6e-26 91.0 0.0 7.6e-26 90.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.20 ETO11084.1 - 3.6e-08 33.4 0.1 7.2e-08 32.4 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 ETO11084.1 - 9.2e-06 25.4 0.0 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 ETO11084.1 - 3.3e-05 23.6 0.0 0.00014 21.6 0.0 2.2 1 0 0 1 1 1 1 Elongation factor G C-terminus Miro PF08477.8 ETO11084.1 - 0.00071 20.0 0.0 0.0014 19.1 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 ETO11084.1 - 0.0017 18.2 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 ETO11084.1 - 0.027 13.8 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 Ras family DUF3450 PF11932.3 ETO11085.1 - 6.1e-05 22.4 0.6 0.00011 21.5 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) TMF_TATA_bd PF12325.3 ETO11085.1 - 0.00035 20.3 1.6 0.00047 19.8 0.3 1.7 2 0 0 2 2 1 1 TATA element modulatory factor 1 TATA binding Filament PF00038.16 ETO11085.1 - 0.00039 19.9 0.3 0.00074 19.0 0.2 1.4 1 0 0 1 1 1 1 Intermediate filament protein CENP-F_leu_zip PF10473.4 ETO11085.1 - 0.00064 19.5 0.8 0.00064 19.5 0.5 1.9 2 0 0 2 2 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.7 ETO11085.1 - 0.0011 19.1 0.7 0.0026 17.9 0.4 1.7 1 1 0 1 1 1 1 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.1 ETO11085.1 - 0.0032 16.0 0.3 0.0053 15.3 0.2 1.3 1 0 0 1 1 1 1 AAA domain DASH_Dad2 PF08654.5 ETO11085.1 - 0.0042 17.0 0.4 0.1 12.6 0.0 2.3 1 1 1 2 2 2 1 DASH complex subunit Dad2 WXG100 PF06013.7 ETO11085.1 - 0.0062 16.5 0.9 0.15 12.1 0.3 2.8 1 1 0 1 1 1 1 Proteins of 100 residues with WXG TMPIT PF07851.8 ETO11085.1 - 0.0066 15.5 0.3 0.0066 15.5 0.2 1.9 2 1 0 2 2 2 1 TMPIT-like protein Claudin_2 PF13903.1 ETO11085.1 - 0.0067 16.1 0.0 0.0094 15.6 0.0 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Laminin_I PF06008.9 ETO11085.1 - 0.01 15.1 1.3 0.016 14.5 0.9 1.3 1 0 0 1 1 1 0 Laminin Domain I TBPIP PF07106.8 ETO11085.1 - 0.01 15.3 0.4 0.02 14.4 0.3 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TPR_MLP1_2 PF07926.7 ETO11085.1 - 0.021 14.5 0.5 0.034 13.8 0.3 1.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein CCDC155 PF14662.1 ETO11085.1 - 0.024 14.2 1.7 0.047 13.2 1.2 1.5 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 Mod_r PF07200.8 ETO11085.1 - 0.029 14.3 1.4 1.4 8.7 0.4 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DivIVA PF05103.8 ETO11085.1 - 0.031 14.3 0.9 0.18 11.8 0.5 2.2 1 1 0 1 1 1 0 DivIVA protein DUF904 PF06005.7 ETO11085.1 - 0.033 14.4 1.8 0.092 13.0 1.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF904) TMF_DNA_bd PF12329.3 ETO11085.1 - 0.05 13.4 1.8 0.16 11.8 1.3 1.9 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF2968 PF11180.3 ETO11085.1 - 0.052 12.9 0.3 0.089 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Reo_sigmaC PF04582.7 ETO11085.1 - 0.058 12.5 0.2 0.14 11.3 0.1 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF2681 PF10883.3 ETO11085.1 - 0.063 13.4 0.0 1.8 8.8 0.0 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) BLOC1_2 PF10046.4 ETO11085.1 - 0.065 13.3 0.8 0.29 11.2 0.6 2.1 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1469 PF07332.6 ETO11085.1 - 0.065 12.9 2.1 0.19 11.4 1.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Tropomyosin_1 PF12718.2 ETO11085.1 - 0.068 13.0 1.1 0.12 12.2 0.8 1.4 1 0 0 1 1 1 0 Tropomyosin like DivIC PF04977.10 ETO11085.1 - 0.072 12.5 1.5 1.9 8.0 0.1 2.7 1 1 1 2 2 2 0 Septum formation initiator DUF4131 PF13567.1 ETO11085.1 - 0.082 12.3 0.2 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Seryl_tRNA_N PF02403.17 ETO11085.1 - 0.086 12.8 0.5 0.24 11.4 0.4 1.8 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.7 ETO11085.1 - 0.1 12.4 1.3 1.8 8.3 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PTS_EIIC PF02378.13 ETO11085.1 - 0.11 11.3 5.6 0.16 10.7 3.9 1.2 1 0 0 1 1 1 0 Phosphotransferase system, EIIC APG6 PF04111.7 ETO11085.1 - 0.11 11.5 1.2 0.17 10.8 0.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 SlyX PF04102.7 ETO11085.1 - 0.12 12.8 0.6 0.4 11.0 0.1 2.1 1 1 1 2 2 2 0 SlyX Laminin_II PF06009.7 ETO11085.1 - 0.13 12.0 0.8 0.43 10.3 0.3 1.9 1 1 1 2 2 2 0 Laminin Domain II HALZ PF02183.13 ETO11085.1 - 0.14 11.8 0.7 16 5.3 0.1 2.7 1 1 1 2 2 2 0 Homeobox associated leucine zipper Baculo_PEP_C PF04513.7 ETO11085.1 - 0.28 10.9 2.4 0.24 11.2 0.6 1.7 2 0 0 2 2 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2570 PF10828.3 ETO11085.1 - 1.7 8.2 5.0 0.74 9.4 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) V_ATPase_I PF01496.14 ETO11085.1 - 2.5 5.8 5.4 0.69 7.6 0.7 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family IncA PF04156.9 ETO11085.1 - 3.2 7.2 18.6 24 4.4 12.9 2.4 1 1 0 1 1 1 0 IncA protein DUF1049 PF06305.6 ETO11085.1 - 3.9 7.0 5.6 1.4 8.4 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1049) LMBR1 PF04791.11 ETO11086.1 - 6.1e-13 48.1 2.5 2.5e-06 26.3 0.0 2.2 1 1 1 2 2 2 2 LMBR1-like membrane protein DUF1469 PF07332.6 ETO11086.1 - 0.05 13.3 3.8 0.2 11.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF3671 PF12420.3 ETO11086.1 - 0.29 11.1 6.8 1.1 9.2 4.7 2.0 1 0 0 1 1 1 0 Protein of unknown function F-box-like PF12937.2 ETO11087.1 - 0.00021 20.9 1.5 0.00047 19.8 1.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETO11087.1 - 0.019 14.6 0.3 0.048 13.3 0.2 1.7 1 0 0 1 1 1 0 F-box domain AAA_11 PF13086.1 ETO11087.1 - 0.045 13.3 0.5 0.063 12.8 0.3 1.2 1 0 0 1 1 1 0 AAA domain DUF4366 PF14283.1 ETO11088.1 - 0.058 12.8 0.1 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) VirB8 PF04335.8 ETO11088.1 - 0.097 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 VirB8 protein Cas_Cmr5 PF09701.5 ETO11090.1 - 0.19 11.9 1.3 0.33 11.1 0.0 2.0 2 1 0 2 2 2 0 CRISPR-associated protein (Cas_Cmr5) HMG_box_2 PF09011.5 ETO11090.1 - 1.1 9.6 3.6 0.9 9.9 0.2 2.3 3 0 0 3 3 3 0 HMG-box domain Golgin_A5 PF09787.4 ETO11092.1 - 0.00078 18.0 5.5 0.00096 17.7 3.8 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 WEMBL PF05701.6 ETO11092.1 - 0.0055 15.2 12.6 0.0076 14.7 8.7 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light HR1 PF02185.11 ETO11092.1 - 0.0061 16.2 9.6 0.026 14.2 1.6 3.2 2 2 1 3 3 3 1 Hr1 repeat Myosin_tail_1 PF01576.14 ETO11092.1 - 0.012 13.4 9.9 0.014 13.1 6.9 1.1 1 0 0 1 1 1 0 Myosin tail Sec1 PF00995.18 ETO11092.1 - 0.012 14.2 2.3 0.014 14.0 1.6 1.2 1 0 0 1 1 1 0 Sec1 family SAM_2 PF07647.12 ETO11092.1 - 0.033 14.0 0.2 0.076 12.8 0.1 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO11092.1 - 0.048 13.8 0.2 0.087 13.0 0.1 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Phage_lysis PF03245.8 ETO11092.1 - 0.086 12.8 1.9 0.15 12.0 0.8 1.7 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein Mnd1 PF03962.10 ETO11092.1 - 0.12 12.0 7.2 0.18 11.4 5.0 1.5 1 1 0 1 1 1 0 Mnd1 family AATF-Che1 PF13339.1 ETO11092.1 - 0.17 12.0 5.7 0.27 11.3 3.7 1.5 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor TBPIP PF07106.8 ETO11092.1 - 0.18 11.3 10.9 0.26 10.8 6.4 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 ETO11092.1 - 0.3 10.6 8.5 0.44 10.1 5.9 1.4 1 1 0 1 1 1 0 IncA protein IFT20 PF14931.1 ETO11092.1 - 0.31 10.9 5.9 0.46 10.3 4.1 1.3 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 PhaP_Bmeg PF09602.5 ETO11092.1 - 0.32 10.8 8.2 0.45 10.3 5.4 1.5 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) CENP-F_leu_zip PF10473.4 ETO11092.1 - 0.91 9.3 14.4 1.5 8.6 9.6 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.7 ETO11092.1 - 2.3 7.9 8.1 0.63 9.7 3.1 1.9 2 1 0 2 2 2 0 Laminin Domain II DUF724 PF05266.9 ETO11092.1 - 3.9 7.0 9.8 12 5.4 5.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) GrpE PF01025.14 ETO11092.1 - 4.3 6.8 9.8 13 5.2 6.8 1.7 1 1 0 1 1 1 0 GrpE EF-hand_7 PF13499.1 ETO11093.1 - 0.00042 20.3 0.5 0.0014 18.6 0.3 2.0 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO11093.1 - 0.00093 18.3 0.5 0.48 9.8 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 ETO11093.1 - 0.006 16.3 0.4 1.5 8.8 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain Med9 PF07544.8 ETO11093.1 - 0.0095 15.6 0.4 0.0095 15.6 0.3 3.1 3 1 0 4 4 4 1 RNA polymerase II transcription mediator complex subunit 9 SICA_C PF12879.2 ETO11093.1 - 0.04 13.7 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 SICA C-terminal inner membrane domain Mem_trans PF03547.13 ETO11093.1 - 0.46 8.7 2.6 0.96 7.6 1.8 1.6 1 0 0 1 1 1 0 Membrane transport protein LMBR1 PF04791.11 ETO11093.1 - 0.6 8.6 6.7 1 7.8 4.6 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Zip PF02535.17 ETO11093.1 - 1.3 8.0 4.4 2.1 7.2 3.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter NOA36 PF06524.7 ETO11093.1 - 1.6 7.9 12.9 2.5 7.2 9.0 1.2 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.7 ETO11093.1 - 1.8 8.2 29.4 0.034 13.8 14.3 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CAML PF14963.1 ETO11093.1 - 2.1 7.6 11.2 0.066 12.5 2.8 2.0 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand Methyltransf_12 PF08242.7 ETO11093.1 - 5.6 7.5 7.5 12 6.3 4.1 2.4 1 1 1 2 2 2 0 Methyltransferase domain DUF1510 PF07423.6 ETO11093.1 - 9.4 5.5 23.9 2.2 7.5 13.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) TH1 PF04858.8 ETO11094.1 - 5.2e-06 24.9 0.1 5.6e-06 24.8 0.1 1.0 1 0 0 1 1 1 1 TH1 protein IL34 PF15036.1 ETO11094.1 - 0.025 14.1 0.2 0.039 13.4 0.1 1.4 2 0 0 2 2 2 0 Interleukin 34 DUF2198 PF09964.4 ETO11094.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2198) TH1 PF04858.8 ETO11095.1 - 0.00016 19.9 1.0 0.029 12.5 0.0 2.4 2 1 0 2 2 2 2 TH1 protein WD40 PF00400.27 ETO11096.1 - 0.005 16.6 3.0 0.18 11.7 0.0 3.7 4 0 0 4 4 4 1 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO11096.1 - 0.019 13.7 0.1 0.024 13.4 0.1 1.1 1 0 0 1 1 1 0 Nup133 N terminal like Ank_2 PF12796.2 ETO11098.1 - 7.1e-12 45.5 0.6 5.7e-07 29.7 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO11098.1 - 2.5e-11 42.6 0.1 0.00028 20.8 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 ETO11098.1 - 3.3e-11 43.0 0.0 5.6e-07 29.6 0.0 4.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO11098.1 - 1.4e-10 41.4 0.0 4.1e-06 27.1 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 ETO11098.1 - 1.5e-07 30.8 0.1 0.00062 19.4 0.0 3.3 4 0 0 4 4 4 2 Ankyrin repeat Myosin_head PF00063.16 ETO11099.1 - 1.2e-10 40.1 0.2 4.6e-07 28.2 0.0 2.1 1 1 1 2 2 2 2 Myosin head (motor domain) DUF1180 PF06679.7 ETO11100.1 - 0.16 11.8 0.2 0.22 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) TMEMspv1-c74-12 PF11044.3 ETO11100.1 - 4.1 7.0 9.4 7.9 6.1 6.5 1.5 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Oscp1 PF10188.4 ETO11104.1 - 5e-48 163.1 10.1 9e-48 162.3 7.0 1.4 1 0 0 1 1 1 1 Organic solute transport protein 1 WD40 PF00400.27 ETO11105.1 - 2.1e-27 93.9 0.6 1.2e-11 43.9 0.1 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO11105.1 - 0.0097 14.0 0.1 1.4 6.9 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO11105.1 - 0.014 15.1 0.2 0.035 13.8 0.2 1.7 1 1 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region OLF PF02191.11 ETO11105.1 - 0.022 14.0 0.6 0.17 11.1 0.0 2.0 1 1 1 2 2 2 0 Olfactomedin-like domain RabGGT_insert PF07711.6 ETO11105.1 - 0.049 13.4 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 Rab geranylgeranyl transferase alpha-subunit, insert domain DUF3586 PF12131.3 ETO11107.1 - 0.065 13.2 4.6 0.29 11.2 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3586) Adeno_E3_CR1 PF02440.10 ETO11107.1 - 0.18 11.3 5.5 2.1 7.8 0.1 3.3 3 0 0 3 3 3 0 Adenovirus E3 region protein CR1 TRAP_alpha PF03896.11 ETO11108.1 - 0.068 12.1 1.0 0.078 11.9 0.7 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit LSR PF05624.9 ETO11108.1 - 0.23 11.2 2.0 0.56 9.9 1.4 1.7 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) DUF21 PF01595.15 ETO11108.1 - 0.36 10.1 5.1 0.45 9.7 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF21 DUF1510 PF07423.6 ETO11108.1 - 0.76 9.1 7.2 1.4 8.2 5.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1510) Nucleoplasmin PF03066.10 ETO11108.1 - 2.2 7.7 8.8 3.4 7.1 6.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin TraF PF13728.1 ETO11109.1 - 0.12 11.8 1.2 0.16 11.4 0.8 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein rpo30_N PF12410.3 ETO11109.1 - 0.18 11.4 1.9 0.2 11.3 0.9 1.3 1 1 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase 30kDa subunit LLC1 PF14945.1 ETO11109.1 - 3.7 7.8 8.0 7.1 6.9 5.6 1.5 1 1 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein C2 PF00168.25 ETO11110.1 - 0.012 15.4 0.8 0.032 14.0 0.2 1.8 2 0 0 2 2 2 0 C2 domain UPF0240 PF06784.6 ETO11110.1 - 0.026 14.1 0.2 0.039 13.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) DUF3877 PF12993.2 ETO11110.1 - 0.044 13.3 0.0 0.094 12.2 0.0 1.5 1 1 1 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) BMFP PF04380.8 ETO11111.1 - 0.0077 16.3 1.6 0.015 15.4 1.1 1.4 1 0 0 1 1 1 1 Membrane fusogenic activity FliD_C PF07195.7 ETO11111.1 - 0.056 12.7 0.5 0.089 12.0 0.3 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Mucin PF01456.12 ETO11112.1 - 0.044 13.5 15.3 0.077 12.7 10.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.7 ETO11112.1 - 0.59 7.8 14.6 0.86 7.2 10.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RP-C_C PF11800.3 ETO11112.1 - 1.9 8.1 8.1 0.45 10.1 3.2 1.7 2 0 0 2 2 2 0 Replication protein C C-terminal region WD40 PF00400.27 ETO11113.1 - 6.6e-21 73.3 9.3 1.6e-12 46.7 0.0 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat zf-TRAF PF02176.13 ETO11113.1 - 0.003 17.8 7.2 0.003 17.8 5.0 1.8 2 0 0 2 2 2 1 TRAF-type zinc finger GspL_C PF12693.2 ETO11113.1 - 0.0096 15.6 0.6 0.015 15.0 0.4 1.3 1 0 0 1 1 1 1 GspL periplasmic domain HOOK PF05622.7 ETO11113.1 - 0.03 12.1 18.1 0.038 11.8 12.6 1.1 1 0 0 1 1 1 0 HOOK protein TSC22 PF01166.13 ETO11113.1 - 0.057 13.3 0.7 0.057 13.3 0.5 3.4 2 1 1 3 3 3 0 TSC-22/dip/bun family DUF641 PF04859.7 ETO11113.1 - 0.073 12.8 13.4 0.27 11.0 2.1 2.3 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Atg14 PF10186.4 ETO11113.1 - 0.46 9.3 23.8 3.3 6.5 16.5 1.9 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Geminin PF07412.7 ETO11113.1 - 0.93 9.1 20.0 0.45 10.1 4.0 2.7 1 1 0 2 2 2 0 Geminin Cep57_CLD_2 PF14197.1 ETO11113.1 - 2.3 8.2 10.7 0.093 12.6 0.9 2.8 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 DUF4239 PF14023.1 ETO11113.1 - 3.9 6.7 6.7 1.5 8.1 2.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) TMPIT PF07851.8 ETO11113.1 - 4.4 6.2 20.4 1.8 7.5 4.1 2.1 1 1 1 2 2 2 0 TMPIT-like protein DUF972 PF06156.8 ETO11113.1 - 4.9 7.5 19.6 0.51 10.7 5.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TPR_MLP1_2 PF07926.7 ETO11113.1 - 6 6.6 23.8 6.8 6.4 6.7 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Kelch_4 PF13418.1 ETO11114.1 - 0.2 11.4 1.2 7.9 6.3 0.0 3.3 4 0 0 4 4 4 0 Galactose oxidase, central domain WD40 PF00400.27 ETO11115.1 - 6.5e-58 190.6 22.3 3.1e-11 42.7 0.4 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO11115.1 - 5e-05 21.6 2.9 1 7.3 0.0 4.7 2 1 2 5 5 5 4 Nucleoporin Nup120/160 SLR1-BP PF07333.7 ETO11115.1 - 0.02 15.1 0.3 0.066 13.4 0.2 1.9 1 0 0 1 1 1 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) NESP55 PF06390.7 ETO11116.1 - 0.58 9.4 5.9 0.86 8.9 4.1 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) DUF2714 PF10896.3 ETO11118.1 - 0.0076 16.0 1.4 0.077 12.7 0.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2714) MR_MLE_N PF02746.11 ETO11119.1 - 9.4e-20 70.7 0.0 1.7e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE_C PF13378.1 ETO11119.1 - 1.7e-19 69.8 0.0 3.2e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 ETO11119.1 - 1.8e-08 34.7 0.0 3.7e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain NACHT PF05729.7 ETO11120.1 - 0.00063 19.4 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain T4_Gp59_C PF08994.5 ETO11120.1 - 0.012 15.7 0.9 0.012 15.7 0.6 3.0 3 1 1 4 4 4 0 T4 gene Gp59 loader of gp41 DNA helicase C-term U-box PF04564.10 ETO11121.1 - 1.3e-12 47.4 0.0 5.2e-12 45.5 0.0 2.2 1 0 0 1 1 1 1 U-box domain Kelch_1 PF01344.20 ETO11121.1 - 0.00011 21.7 1.0 0.00026 20.4 0.7 1.7 1 0 0 1 1 1 1 Kelch motif Kelch_6 PF13964.1 ETO11121.1 - 0.00033 20.6 0.6 0.00088 19.3 0.4 1.6 1 0 0 1 1 1 1 Kelch motif Kelch_3 PF13415.1 ETO11121.1 - 0.00074 19.6 0.0 0.0017 18.5 0.0 1.5 1 0 0 1 1 1 1 Galactose oxidase, central domain MbeD_MobD PF04899.7 ETO11121.1 - 0.0031 17.3 0.1 0.015 15.1 0.1 2.2 1 1 0 1 1 1 1 MbeD/MobD like DUF2205 PF10224.4 ETO11121.1 - 0.0037 16.8 0.8 0.0037 16.8 0.5 2.4 3 0 0 3 3 3 1 Predicted coiled-coil protein (DUF2205) Kelch_2 PF07646.10 ETO11121.1 - 0.0098 15.6 1.3 0.029 14.1 0.4 2.2 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.1 ETO11121.1 - 0.014 15.1 0.5 0.029 14.1 0.0 1.7 2 0 0 2 2 2 0 Galactose oxidase, central domain zf-Nse PF11789.3 ETO11121.1 - 0.091 12.2 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Cytochrom_B_N PF00033.14 ETO11122.1 - 0.074 12.4 0.1 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB CENP-T PF15511.1 ETO11122.1 - 0.21 10.7 18.3 0.23 10.6 12.7 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIIA PF03153.8 ETO11122.1 - 0.82 9.5 24.3 0.82 9.5 16.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PPP4R2 PF09184.6 ETO11122.1 - 3.8 6.9 29.2 5 6.5 20.3 1.2 1 0 0 1 1 1 0 PPP4R2 Ank_5 PF13857.1 ETO11123.1 - 7.6e-07 29.1 0.2 3.3e-06 27.1 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 ETO11123.1 - 2.7e-05 23.7 0.0 0.00014 21.4 0.0 2.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 ETO11123.1 - 6.2e-05 22.8 0.3 0.00063 19.7 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 ETO11123.1 - 0.00049 20.3 2.1 0.002 18.3 0.4 2.6 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) RPT PF13446.1 ETO11123.1 - 0.0088 15.4 0.1 0.035 13.5 0.1 2.0 1 0 0 1 1 1 1 A repeated domain in UCH-protein Ank_4 PF13637.1 ETO11123.1 - 0.029 14.8 2.3 0.071 13.6 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeats (many copies) FA_desaturase PF00487.19 ETO11125.1 - 1.6e-12 47.3 9.4 2.1e-12 47.0 6.5 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Methyltransf_11 PF08241.7 ETO11127.1 - 1.3e-05 25.6 0.0 3.3e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETO11127.1 - 2.9e-05 23.8 0.2 4.1e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO11127.1 - 0.00056 19.5 0.0 0.0028 17.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 ETO11127.1 - 0.0011 18.6 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO11127.1 - 0.0018 18.8 0.0 0.052 14.1 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETO11127.1 - 0.0025 18.1 0.0 0.0074 16.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 ETO11127.1 - 0.033 13.7 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 ETO11127.1 - 0.061 13.7 0.0 0.6 10.6 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain TatD_DNase PF01026.16 ETO11128.1 - 1.5e-22 80.0 0.2 2.3e-22 79.4 0.1 1.3 1 1 0 1 1 1 1 TatD related DNase PsbP PF01789.11 ETO11128.1 - 0.083 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 PsbP Pkinase PF00069.20 ETO11129.1 - 2.1e-59 200.8 0.0 3.2e-41 141.2 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO11129.1 - 7.3e-27 94.0 0.0 1.4e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FAM104 PF15434.1 ETO11129.1 - 0.018 15.2 0.6 0.072 13.3 0.4 2.0 1 0 0 1 1 1 0 Family 104 AAA_24 PF13479.1 ETO11129.1 - 0.038 13.5 0.3 0.069 12.7 0.2 1.4 1 0 0 1 1 1 0 AAA domain APH PF01636.18 ETO11129.1 - 0.11 12.2 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Activator_LAG-3 PF11498.3 ETO11129.1 - 0.14 10.8 0.5 0.23 10.1 0.3 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Methyltrn_RNA_4 PF09936.4 ETO11130.1 - 0.12 11.8 2.0 0.14 11.6 1.3 1.3 1 1 0 1 1 1 0 SAM-dependent RNA methyltransferase VirC2 PF07181.6 ETO11130.1 - 0.69 9.2 3.7 0.42 9.9 1.2 1.6 1 1 0 1 1 1 0 VirC2 protein SprA-related PF12118.3 ETO11130.1 - 3 7.1 13.6 3.5 6.8 9.4 1.0 1 0 0 1 1 1 0 SprA-related family Ykof PF07615.6 ETO11130.1 - 3.3 7.9 4.9 1.6 8.9 0.8 1.9 2 0 0 2 2 2 0 YKOF-related Family DUF3490 PF11995.3 ETO11132.1 - 0.017 14.6 1.1 0.058 12.9 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3490) Bro-N PF02498.12 ETO11132.1 - 0.031 14.5 2.1 0.038 14.2 0.2 2.0 2 1 0 2 2 2 0 BRO family, N-terminal domain EF-hand_7 PF13499.1 ETO11134.1 - 0.005 16.9 0.1 0.0073 16.4 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair Arrestin_C PF02752.17 ETO11134.1 - 0.025 14.6 0.0 0.027 14.5 0.0 1.2 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain EF-hand_6 PF13405.1 ETO11134.1 - 0.084 12.8 0.1 2.1 8.4 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain Tubulin_C PF03953.12 ETO11135.1 - 2.7e-36 124.4 0.0 3.8e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 ETO11135.1 - 4.5e-07 29.9 0.0 8.4e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain WD40 PF00400.27 ETO11137.1 - 4.8e-36 121.3 9.2 2.3e-12 46.2 0.1 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO11137.1 - 2.1e-09 36.1 0.4 0.001 17.2 0.0 2.7 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Peptidase_A22B PF04258.8 ETO11138.1 - 1.5e-49 169.1 12.7 3.5e-49 167.8 8.8 1.6 1 0 0 1 1 1 1 Signal peptide peptidase DUF1352 PF07086.7 ETO11139.1 - 0.32 10.5 6.6 0.32 10.6 0.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1352) DUF1467 PF07330.7 ETO11139.1 - 1.1 9.0 5.4 0.62 9.8 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1467) Corona_NS3b PF03053.9 ETO11139.1 - 2.1 7.8 12.1 5.7 6.4 4.7 2.2 2 0 0 2 2 2 0 ORF3b coronavirus protein TPR_11 PF13414.1 ETO11140.1 - 7.2e-12 44.7 13.0 9.5e-06 25.1 0.3 6.2 5 1 0 5 5 5 3 TPR repeat TPR_12 PF13424.1 ETO11140.1 - 6.5e-07 29.1 10.7 0.27 11.2 0.4 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO11140.1 - 0.00015 21.9 0.1 2.8 8.3 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO11140.1 - 0.0015 18.1 9.4 0.31 10.9 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO11140.1 - 0.0042 16.8 13.3 8.7 6.5 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO11140.1 - 0.027 15.0 0.0 14 6.6 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETO11140.1 - 0.033 13.7 10.9 0.1 12.2 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETO11140.1 - 0.051 14.2 0.0 30 5.4 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO11140.1 - 0.06 13.8 1.1 37 5.0 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Utp14 PF04615.8 ETO11140.1 - 4.4 5.3 50.7 9.9 4.1 33.7 2.2 2 0 0 2 2 2 0 Utp14 protein IncA PF04156.9 ETO11141.1 - 0.0034 17.0 7.5 0.0043 16.6 4.8 1.4 1 1 0 1 1 1 1 IncA protein Laminin_I PF06008.9 ETO11141.1 - 0.0052 16.1 8.2 0.013 14.8 5.7 1.7 1 1 0 1 1 1 1 Laminin Domain I DUF1342 PF07072.6 ETO11141.1 - 0.031 13.9 1.5 0.031 13.9 1.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1342) Bacillus_HBL PF05791.6 ETO11141.1 - 0.038 13.3 10.5 0.22 10.8 7.3 2.0 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Ndc1_Nup PF09531.5 ETO11141.1 - 0.048 12.0 2.8 0.058 11.8 1.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Lipoprotein_2 PF00921.12 ETO11141.1 - 0.051 13.6 4.2 0.094 12.7 2.6 1.7 1 1 0 1 1 1 0 Borrelia lipoprotein Rop-like PF05082.8 ETO11141.1 - 0.076 12.5 1.4 0.13 11.7 0.2 1.9 2 0 0 2 2 2 0 Rop-like G-gamma PF00631.17 ETO11141.1 - 0.08 12.7 0.4 0.23 11.2 0.2 1.9 1 0 0 1 1 1 0 GGL domain Neur_chan_memb PF02932.11 ETO11141.1 - 0.28 11.0 5.7 0.43 10.4 4.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4407 PF14362.1 ETO11141.1 - 0.36 9.7 9.2 0.49 9.2 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1515 PF07439.6 ETO11141.1 - 0.4 10.5 3.1 0.22 11.3 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Mnd1 PF03962.10 ETO11141.1 - 0.5 9.9 11.6 0.78 9.3 7.7 1.6 1 1 0 1 1 1 0 Mnd1 family DUF4482 PF14818.1 ETO11141.1 - 1.1 9.9 11.6 0.046 14.3 2.8 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4482) COG2 PF06148.6 ETO11141.1 - 1.2 9.0 6.2 0.25 11.2 0.6 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4404 PF14357.1 ETO11141.1 - 2.1 8.8 6.8 3.2 8.2 2.9 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4404) V_ATPase_I PF01496.14 ETO11141.1 - 2.3 5.9 6.9 2.7 5.7 4.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlxA PF14282.1 ETO11141.1 - 3.3 7.7 25.8 12 5.8 6.5 3.0 1 1 2 3 3 3 0 FlxA-like protein Bap31 PF05529.7 ETO11141.1 - 4 6.8 11.3 2.4e+02 1.0 9.7 2.4 2 1 0 2 2 2 0 B-cell receptor-associated protein 31-like Cytochrom_B562 PF07361.6 ETO11141.1 - 4.9 7.6 11.4 1.5 9.3 4.7 2.1 1 1 1 2 2 2 0 Cytochrome b562 AAA_13 PF13166.1 ETO11141.1 - 5.9 5.2 14.1 7.8 4.8 9.8 1.1 1 0 0 1 1 1 0 AAA domain DUF2361 PF10153.4 ETO11141.1 - 8.3 6.6 16.3 1.2e+02 2.8 2.3 2.3 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2361) Metallophos PF00149.23 ETO11143.1 - 2.1e-09 37.0 5.7 1.3e-08 34.4 3.9 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 ETO11143.1 - 1.1e-08 35.1 2.1 5.4e-08 32.8 1.5 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Integrase_DNA PF02920.10 ETO11143.1 - 0.1 12.0 2.1 0.17 11.3 0.4 2.1 2 0 0 2 2 2 0 DNA binding domain of tn916 integrase PEGA PF08308.6 ETO11143.1 - 0.12 12.2 0.1 0.89 9.3 0.0 2.2 2 0 0 2 2 2 0 PEGA domain Pkinase PF00069.20 ETO11145.1 - 7.8e-11 41.6 0.5 2.4e-09 36.7 0.0 2.5 2 0 0 2 2 2 1 Protein kinase domain NAF PF03822.9 ETO11145.1 - 0.00015 21.4 0.1 0.00075 19.1 0.0 2.2 2 0 0 2 2 2 1 NAF domain DUF4516 PF14990.1 ETO11145.1 - 0.079 12.5 0.4 0.21 11.1 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) DUF3276 PF11680.3 ETO11145.1 - 7.1 6.4 10.9 0.087 12.6 0.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3276) Porph_ging PF09697.5 ETO11146.1 - 2.2 8.4 4.6 0.96 9.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (Porph_ging) RRF PF01765.14 ETO11147.1 - 7.4e-16 58.0 4.9 7.4e-16 58.0 3.4 1.3 1 1 0 1 1 1 1 Ribosome recycling factor DUF3832 PF12909.2 ETO11147.1 - 0.022 14.7 0.0 0.17 11.9 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3832) Hemerythrin PF01814.18 ETO11147.1 - 0.086 13.0 0.2 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain GnsAB PF08178.6 ETO11147.1 - 2.1 8.0 5.8 2.8 7.6 0.6 2.8 2 1 0 2 2 2 0 GnsA/GnsB family Exo_endo_phos_2 PF14529.1 ETO11148.1 - 5.4e-06 26.0 0.2 5.4e-06 26.0 0.2 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase DUF327 PF03885.8 ETO11148.1 - 0.004 17.0 0.1 0.004 17.0 0.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF327) Herpes_UL49_2 PF04823.7 ETO11148.1 - 0.032 14.1 0.6 0.086 12.8 0.4 1.7 1 0 0 1 1 1 0 Herpesvirus UL49 tegument protein Opiods_neuropep PF01160.13 ETO11148.1 - 0.12 12.1 0.1 0.29 10.9 0.1 1.6 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide PT PF04886.7 ETO11151.1 - 1.5e-29 100.9 163.1 4.4e-05 22.7 12.7 9.1 3 2 3 6 6 6 5 PT repeat VWA_2 PF13519.1 ETO11151.1 - 0.0025 17.9 0.0 0.0033 17.5 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 ETO11151.1 - 0.097 12.3 0.1 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain VWA PF00092.23 ETO11152.1 - 0.00019 21.2 0.1 0.002 17.8 0.1 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 ETO11152.1 - 0.0022 18.1 0.0 0.0032 17.5 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Gloverin PF10793.4 ETO11152.1 - 0.073 12.7 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Gloverin-like protein Peptidase_C13 PF01650.13 ETO11153.1 - 3.8e-18 65.7 1.3 1.1e-17 64.1 0.9 1.6 1 1 0 1 1 1 1 Peptidase C13 family CRCB PF02537.10 ETO11154.1 - 1.5e-06 28.0 0.3 1.5e-06 28.0 0.2 1.6 2 0 0 2 2 2 1 CrcB-like protein zf-4CXXC_R1 PF10497.4 ETO11155.1 - 0.062 13.4 7.6 0.2 11.7 5.2 1.8 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 CDC45 PF02724.9 ETO11155.1 - 0.5 8.3 25.7 0.076 11.0 0.1 2.4 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.7 ETO11155.1 - 0.68 7.7 39.8 0.85 7.4 0.9 2.2 2 0 0 2 2 2 0 Nop14-like family SDA1 PF05285.7 ETO11155.1 - 2.6 7.2 43.8 1.6 7.9 1.3 2.1 2 0 0 2 2 2 0 SDA1 RIC3 PF15361.1 ETO11155.1 - 6.4 6.9 8.3 70 3.6 0.0 2.5 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 UPF0564 PF10595.4 ETO11157.1 - 0.12 11.2 5.5 0.16 10.8 3.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 E2_bind PF08825.5 ETO11158.1 - 0.046 13.4 0.7 0.18 11.5 0.0 2.1 1 1 1 2 2 2 0 E2 binding domain Fmp27_GFWDK PF10347.4 ETO11158.1 - 0.094 12.6 0.8 0.22 11.4 0.6 1.6 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF3492 PF11997.3 ETO11158.1 - 0.12 11.8 1.7 0.14 11.7 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) Cu_amine_oxid PF01179.15 ETO11158.1 - 0.46 9.1 3.0 0.58 8.8 2.1 1.1 1 0 0 1 1 1 0 Copper amine oxidase, enzyme domain Toxin_52 PF15605.1 ETO11158.1 - 2 8.3 0.0 2 8.3 0.0 2.7 2 1 1 3 3 3 0 Putative toxin 52 PTEN_C2 PF10409.4 ETO11161.1 - 0.017 14.8 0.4 0.029 14.1 0.2 1.5 1 1 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein Glyco_hydro_92 PF07971.7 ETO11162.1 - 0.024 13.2 0.7 0.033 12.8 0.5 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 92 Rrp15p PF07890.7 ETO11162.1 - 0.029 14.4 1.8 0.033 14.2 1.3 1.2 1 0 0 1 1 1 0 Rrp15p SpoVIF PF14069.1 ETO11162.1 - 0.053 13.2 3.5 0.38 10.5 1.4 2.1 1 1 1 2 2 2 0 Stage VI sporulation protein F Mga PF05043.8 ETO11162.1 - 0.1 12.9 0.1 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Mga helix-turn-helix domain RAI1 PF08652.6 ETO11162.1 - 2 8.2 5.5 1.9 8.3 0.6 2.3 2 0 0 2 2 2 0 RAI1 like PD-(D/E)XK nuclease WD40 PF00400.27 ETO11164.1 - 2.1e-26 90.7 6.0 2.8e-09 36.4 0.0 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO11164.1 - 1.9e-05 23.0 1.6 0.098 10.7 0.0 3.0 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO11164.1 - 0.0051 15.6 3.6 0.76 8.4 0.1 2.9 1 1 2 3 3 3 3 Nup133 N terminal like Sulfatase PF00884.18 ETO11165.1 - 2.9e-14 52.9 0.6 3.8e-14 52.6 0.4 1.1 1 0 0 1 1 1 1 Sulfatase DUF3038 PF11237.3 ETO11167.1 - 0.95 9.2 6.7 0.34 10.6 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3038) PPO1_KFDV PF12143.3 ETO11167.1 - 1.8 8.4 6.6 0.17 11.7 1.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF_B2219) LCAT PF02450.10 ETO11168.1 - 1.2e-57 195.6 2.3 2e-42 145.5 1.4 2.6 2 1 0 2 2 2 2 Lecithin:cholesterol acyltransferase Aa_trans PF01490.13 ETO11169.1 - 5.1e-17 61.4 16.0 6.7e-17 61.0 11.1 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Erg28 PF03694.8 ETO11169.1 - 0.035 14.1 4.1 0.24 11.4 0.6 2.6 2 0 0 2 2 2 0 Erg28 like protein Pkinase PF00069.20 ETO11170.1 - 4.4e-37 127.6 2.5 2.5e-35 121.8 0.5 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO11170.1 - 8.3e-20 70.9 0.2 1.5e-19 70.1 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO11170.1 - 0.0017 17.4 0.0 0.0029 16.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETO11170.1 - 0.015 14.2 0.4 0.056 12.4 0.0 2.0 3 0 0 3 3 3 0 Kinase-like APH PF01636.18 ETO11170.1 - 0.066 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Exonuc_VII_L PF02601.10 ETO11171.1 - 0.34 10.0 4.5 0.37 9.9 3.1 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spt5_N PF11942.3 ETO11171.1 - 4.1 8.0 6.1 5.3 7.7 4.2 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Protocadherin PF08374.6 ETO11171.1 - 6.8 6.2 8.9 7.1 6.1 6.1 1.1 1 0 0 1 1 1 0 Protocadherin Myosin_HC-like PF07058.6 ETO11172.1 - 0.067 12.2 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Myosin II heavy chain-like Atrophin-1 PF03154.10 ETO11174.1 - 0.036 12.2 9.5 0.053 11.6 6.6 1.2 1 0 0 1 1 1 0 Atrophin-1 family DDHD PF02862.12 ETO11174.1 - 0.24 11.1 1.5 0.33 10.7 1.0 1.2 1 0 0 1 1 1 0 DDHD domain zf-DNA_Pol PF08996.5 ETO11174.1 - 1.2 8.4 4.5 0.75 9.1 0.1 2.1 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger DUF4612 PF15389.1 ETO11174.1 - 3.8 8.1 11.4 3.4 8.2 0.5 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4612) DUF1777 PF08648.7 ETO11174.1 - 4.1 7.1 20.5 0.59 9.8 8.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Beach PF02138.13 ETO11175.1 - 2.7e-43 148.3 0.4 1.5e-42 145.9 0.1 2.4 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.1 ETO11175.1 - 3.2e-13 49.4 0.1 2.5e-12 46.5 0.1 2.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF3974 PF13120.1 ETO11175.1 - 2 8.2 10.8 0.41 10.4 0.9 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3974) Laminin_G_3 PF13385.1 ETO11177.1 - 6.2e-08 33.0 0.0 1.7e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily SAM_2 PF07647.12 ETO11178.1 - 0.0053 16.5 0.6 0.016 15.0 0.4 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CLN5 PF15014.1 ETO11178.1 - 0.028 13.7 0.2 5.2 6.3 0.0 2.3 2 0 0 2 2 2 0 Ceroid-lipofuscinosis neuronal protein 5 SAM_1 PF00536.25 ETO11178.1 - 0.34 11.1 5.3 0.083 13.0 0.5 2.3 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) CAP_GLY PF01302.20 ETO11179.1 - 2.4e-10 39.9 0.1 4.7e-10 39.0 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain MIP-T3 PF10243.4 ETO11179.1 - 0.0011 17.5 5.6 0.0013 17.3 3.9 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Mitofilin PF09731.4 ETO11179.1 - 0.22 10.1 4.6 0.31 9.6 3.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DDHD PF02862.12 ETO11179.1 - 4.4 7.0 8.3 9 6.0 5.7 1.6 1 1 0 1 1 1 0 DDHD domain Mnd1 PF03962.10 ETO11181.1 - 6.8e-30 104.1 12.2 5.4e-29 101.2 6.2 2.1 1 1 1 2 2 2 1 Mnd1 family CCDC-167 PF15188.1 ETO11181.1 - 0.01 15.7 4.0 0.16 11.9 0.2 3.4 4 0 0 4 4 3 0 Coiled-coil domain-containing protein 167 TBPIP PF07106.8 ETO11181.1 - 0.013 15.0 7.3 0.074 12.6 3.9 2.4 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF904 PF06005.7 ETO11181.1 - 0.023 14.9 6.7 1.8 8.9 0.1 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF904) THOC7 PF05615.8 ETO11181.1 - 0.029 14.6 0.5 0.029 14.6 0.3 2.6 3 1 0 3 3 2 0 Tho complex subunit 7 LUC7 PF03194.10 ETO11181.1 - 0.033 13.7 2.9 0.99 8.8 2.0 2.2 1 1 0 1 1 1 0 LUC7 N_terminus Synaptonemal_3 PF15191.1 ETO11181.1 - 0.034 13.8 0.6 0.21 11.3 0.0 2.4 2 1 0 3 3 3 0 Synaptonemal complex central element protein 3 PUL PF08324.6 ETO11181.1 - 0.042 12.6 0.2 0.042 12.6 0.2 1.8 2 0 0 2 2 2 0 PUL domain CENP-F_leu_zip PF10473.4 ETO11181.1 - 0.057 13.2 0.6 0.057 13.2 0.4 2.8 4 0 0 4 4 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sec8_exocyst PF04048.9 ETO11181.1 - 0.067 12.8 2.3 4.7 6.8 0.1 2.3 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF1192 PF06698.6 ETO11181.1 - 0.098 12.4 0.8 0.29 10.9 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF4094 PF13334.1 ETO11181.1 - 0.11 12.8 3.4 0.13 12.6 0.1 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF4094) DUF2533 PF10752.4 ETO11181.1 - 0.12 12.6 0.3 0.12 12.6 0.2 2.2 3 0 0 3 3 2 0 Protein of unknown function (DUF2533) DivIC PF04977.10 ETO11181.1 - 0.15 11.5 4.0 0.13 11.7 0.9 2.2 2 0 0 2 2 2 0 Septum formation initiator BLOC1_2 PF10046.4 ETO11181.1 - 0.16 12.0 5.7 0.56 10.3 0.6 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prefoldin_2 PF01920.15 ETO11181.1 - 0.23 11.2 5.7 0.15 11.7 0.8 2.7 2 0 0 2 2 2 0 Prefoldin subunit TMF_DNA_bd PF12329.3 ETO11181.1 - 0.32 10.8 10.9 0.066 13.0 2.5 3.1 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF3847 PF12958.2 ETO11181.1 - 0.5 10.1 3.6 2.8 7.7 0.3 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF3847) DUF4618 PF15397.1 ETO11181.1 - 0.69 9.2 7.2 0.41 9.9 2.0 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4618) Uds1 PF15456.1 ETO11181.1 - 1.1 9.2 7.9 0.29 11.1 1.0 2.7 2 1 1 3 3 3 0 Up-regulated During Septation TPR_MLP1_2 PF07926.7 ETO11181.1 - 1.8 8.3 10.7 8.9 6.0 7.4 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Phasin PF05597.6 ETO11181.1 - 1.8 8.3 8.0 0.57 9.9 0.9 2.8 3 1 1 4 4 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1024 PF06260.7 ETO11181.1 - 1.9 8.6 6.2 1.1 9.5 0.1 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1024) TipAS PF07739.8 ETO11181.1 - 2 8.7 8.0 0.5 10.7 0.3 2.6 2 1 0 3 3 3 0 TipAS antibiotic-recognition domain Ead_Ea22 PF13935.1 ETO11181.1 - 2.4 8.4 6.9 10 6.4 4.8 2.0 1 1 0 1 1 1 0 Ead/Ea22-like protein Fib_alpha PF08702.5 ETO11181.1 - 3.9 7.5 8.5 20 5.2 0.1 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.17 ETO11181.1 - 5.7 7.0 11.5 0.95 9.5 2.7 2.9 2 2 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain HSCB_C PF07743.8 ETO11181.1 - 9.8 6.7 8.2 17 5.9 0.2 2.9 3 0 0 3 3 2 0 HSCB C-terminal oligomerisation domain Pkinase PF00069.20 ETO11182.1 - 6.3e-05 22.2 0.0 6.3e-05 22.2 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Ponericin PF07442.6 ETO11182.1 - 0.024 14.4 0.2 0.047 13.5 0.1 1.4 1 0 0 1 1 1 0 Ponericin Ras PF00071.17 ETO11184.1 - 4.9e-25 87.8 0.1 4.9e-25 87.8 0.1 1.4 2 0 0 2 2 2 1 Ras family Miro PF08477.8 ETO11184.1 - 2.9e-06 27.7 0.3 7.7e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO11184.1 - 7.2e-05 22.1 0.2 0.0003 20.0 0.0 1.8 1 1 1 2 2 2 1 ADP-ribosylation factor family TMF_DNA_bd PF12329.3 ETO11185.1 - 0.0036 17.0 8.7 0.0036 17.0 6.0 2.7 2 1 0 2 2 2 1 TATA element modulatory factor 1 DNA binding MutS_IV PF05190.13 ETO11185.1 - 0.0054 16.8 4.4 0.011 15.9 3.0 1.4 1 0 0 1 1 1 1 MutS family domain IV DUF812 PF05667.6 ETO11185.1 - 0.0086 14.6 15.7 0.01 14.3 10.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Macoilin PF09726.4 ETO11185.1 - 0.023 13.0 17.4 0.026 12.8 12.1 1.0 1 0 0 1 1 1 0 Transmembrane protein Spc7 PF08317.6 ETO11185.1 - 0.042 12.5 13.2 0.04 12.5 8.7 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein ATG16 PF08614.6 ETO11185.1 - 0.044 13.6 17.1 0.067 13.0 11.9 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF3782 PF12644.2 ETO11185.1 - 0.065 13.0 0.8 0.11 12.2 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) Borrelia_orfA PF02414.10 ETO11185.1 - 0.13 11.3 23.2 0.16 11.0 16.1 1.1 1 0 0 1 1 1 0 Borrelia ORF-A DUF4047 PF13256.1 ETO11185.1 - 0.37 10.7 13.3 0.88 9.5 4.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) DUF745 PF05335.8 ETO11185.1 - 0.85 9.1 14.2 0.02 14.4 4.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF16 PF01519.11 ETO11185.1 - 1.1 9.5 17.3 1.2e+02 3.0 12.0 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 UPF0449 PF15136.1 ETO11185.1 - 3.6 7.8 6.9 1.4 9.1 2.2 2.3 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 SlyX PF04102.7 ETO11185.1 - 4.4 7.7 9.8 0.34 11.2 2.0 2.6 2 1 1 3 3 3 0 SlyX Fmp27_WPPW PF10359.4 ETO11185.1 - 5.5 5.2 20.1 2.8 6.2 4.9 2.1 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Fib_alpha PF08702.5 ETO11185.1 - 9.6 6.3 18.0 1.5 8.8 7.1 2.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family WD40 PF00400.27 ETO11186.1 - 0.00012 21.8 0.3 0.0002 21.1 0.2 1.3 1 0 0 1 1 1 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO11186.1 - 0.04 12.0 0.0 0.044 11.9 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 tRNA-synt_2e PF02091.10 ETO11188.1 - 0.074 12.1 0.5 0.1 11.6 0.3 1.2 1 0 0 1 1 1 0 Glycyl-tRNA synthetase alpha subunit PTPlike_phytase PF14566.1 ETO11188.1 - 0.12 12.4 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Ago_hook PF10427.4 ETO11189.1 - 0.07 13.1 1.1 0.081 12.9 0.7 1.1 1 0 0 1 1 1 0 Argonaute hook PapD_N PF00345.15 ETO11191.1 - 0.034 13.9 1.4 0.063 13.0 0.0 2.2 2 0 0 2 2 2 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain IncA PF04156.9 ETO11191.1 - 0.12 11.9 6.2 0.063 12.8 1.7 2.1 2 0 0 2 2 2 0 IncA protein Sporozoite_P67 PF05642.6 ETO11191.1 - 0.16 9.7 6.4 0.22 9.3 4.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Daxx PF03344.10 ETO11191.1 - 0.27 9.6 16.9 0.34 9.3 11.7 1.1 1 0 0 1 1 1 0 Daxx Family POX PF07526.6 ETO11191.1 - 0.34 11.1 9.4 0.21 11.7 4.8 2.0 1 1 0 1 1 1 0 Associated with HOX PBP1_TM PF14812.1 ETO11191.1 - 0.38 11.0 7.9 1 9.6 5.5 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal OmpH PF03938.9 ETO11191.1 - 0.48 10.3 7.0 1 9.3 4.8 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RNA_pol_3_Rpc31 PF11705.3 ETO11191.1 - 1.2 9.0 20.6 0.047 13.6 3.7 2.5 2 1 1 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.5 ETO11191.1 - 1.2 9.4 8.6 2.6 8.3 5.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 ETO11191.1 - 3.5 7.1 9.9 7.3 6.0 6.9 1.5 1 0 0 1 1 1 0 Nucleoplasmin Pkinase PF00069.20 ETO11192.1 - 0.0011 18.2 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF4562 PF15123.1 ETO11192.1 - 0.0032 17.3 0.3 0.0051 16.6 0.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4562) IL34 PF15036.1 ETO11192.1 - 0.041 13.4 0.2 0.046 13.2 0.1 1.1 1 0 0 1 1 1 0 Interleukin 34 CM_1 PF07736.6 ETO11192.1 - 0.087 12.9 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Chorismate mutase type I RGS PF00615.14 ETO11193.1 - 7.5e-08 32.4 3.5 7.5e-08 32.4 2.4 2.5 2 0 0 2 2 2 1 Regulator of G protein signaling domain PH_11 PF15413.1 ETO11193.1 - 1.3e-07 31.8 3.3 1.3e-07 31.8 2.3 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 ETO11193.1 - 6.8e-07 29.4 3.7 6.8e-07 29.4 2.6 2.4 3 0 0 3 3 3 1 PH domain RA PF00788.18 ETO11193.1 - 1.4e-06 28.6 0.0 3.9e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PH_4 PF15404.1 ETO11193.1 - 0.0051 16.3 0.9 0.013 15.0 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain RBD PF02196.10 ETO11193.1 - 0.026 14.2 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 Raf-like Ras-binding domain DUF3612 PF12268.3 ETO11193.1 - 0.091 12.5 0.0 13 5.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3612) PH_8 PF15409.1 ETO11193.1 - 0.69 10.0 6.4 18 5.4 0.0 3.5 3 0 0 3 3 3 0 Pleckstrin homology domain La PF05383.12 ETO11194.1 - 1.4e-18 66.4 0.2 3.1e-18 65.3 0.1 1.6 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 ETO11194.1 - 3.2e-05 23.4 0.1 0.0037 16.8 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO11194.1 - 0.002 18.0 0.0 0.11 12.5 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CesT PF05932.8 ETO11194.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Tir chaperone protein (CesT) family Peptidase_S49_N PF08496.5 ETO11194.1 - 0.56 9.9 5.7 0.56 9.9 1.6 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal CAP_GLY PF01302.20 ETO11195.1 - 5.7e-13 48.3 0.0 1.3e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 CAP-Gly domain WBP-1 PF11669.3 ETO11195.1 - 0.018 15.1 0.6 5.6 7.0 0.2 2.9 2 0 0 2 2 2 0 WW domain-binding protein 1 ER_lumen_recept PF00810.13 ETO11196.1 - 3e-47 160.8 21.2 8.5e-32 110.6 6.6 2.7 2 1 1 3 3 3 2 ER lumen protein retaining receptor PQ-loop PF04193.9 ETO11196.1 - 0.026 14.0 0.9 0.026 14.0 0.6 3.4 4 1 0 4 4 4 0 PQ loop repeat PIG-P PF08510.7 ETO11196.1 - 8.2 6.0 13.8 0.41 10.2 4.6 2.3 1 1 1 2 2 2 0 PIG-P Y_phosphatase2 PF03162.8 ETO11197.1 - 1.8e-29 102.2 0.8 3.5e-29 101.2 0.5 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family TPR_2 PF07719.12 ETO11198.1 - 0.017 14.9 0.2 0.16 11.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETO11198.1 - 0.022 14.4 0.5 0.1 12.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2095 PF09868.4 ETO11199.1 - 0.019 14.7 0.4 0.019 14.7 0.3 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2095) BBS1 PF14779.1 ETO11199.1 - 0.24 10.3 1.6 0.18 10.7 0.1 1.5 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 1 NUDIX PF00293.23 ETO11200.1 - 8.7e-06 25.4 0.0 1.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain MRP-L46 PF11788.3 ETO11200.1 - 0.016 15.8 7.8 0.19 12.3 2.8 2.9 1 1 1 2 2 2 0 39S mitochondrial ribosomal protein L46 Senescence_reg PF04520.8 ETO11200.1 - 0.29 11.6 2.8 3.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Senescence regulator Orthopox_B11R PF07033.6 ETO11200.1 - 0.42 10.1 0.1 0.42 10.1 0.1 2.9 3 1 0 3 3 3 0 Orthopoxvirus B11R protein RRM_1 PF00076.17 ETO11201.1 - 2.8e-22 78.1 0.1 2.2e-16 59.2 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO11201.1 - 9.9e-16 57.4 0.1 2.8e-10 40.0 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO11201.1 - 1.1e-13 50.7 0.1 2.8e-09 36.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transposase_22 PF02994.9 ETO11201.1 - 0.012 14.1 0.0 0.016 13.7 0.0 1.2 1 0 0 1 1 1 0 L1 transposable element DUF1777 PF08648.7 ETO11201.1 - 1.8 8.2 9.4 0.3 10.7 4.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) EF-hand_8 PF13833.1 ETO11202.1 - 0.0005 19.6 0.1 0.00097 18.7 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 ETO11202.1 - 0.0063 16.6 0.3 0.015 15.3 0.0 1.7 2 0 0 2 2 2 1 EF-hand domain pair Tetraspannin PF00335.15 ETO11202.1 - 5.3 6.2 6.1 7.9 5.6 4.3 1.2 1 0 0 1 1 1 0 Tetraspanin family ABC2_membrane_3 PF12698.2 ETO11202.1 - 6.8 5.6 10.3 8.1 5.3 7.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein TIP_N PF12457.3 ETO11203.1 - 0.0067 16.4 0.2 0.031 14.3 0.1 2.2 1 0 0 1 1 1 1 Tuftelin interacting protein N terminal HEAT PF02985.17 ETO11204.1 - 0.027 14.5 0.4 0.52 10.5 0.1 2.6 2 0 0 2 2 2 0 HEAT repeat HEAT_2 PF13646.1 ETO11204.1 - 0.03 14.6 0.0 9.9 6.5 0.0 2.5 2 0 0 2 2 2 0 HEAT repeats PG_binding_2 PF08823.6 ETO11204.1 - 0.056 13.5 0.5 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Putative peptidoglycan binding domain TCP PF03634.8 ETO11204.1 - 4.6 7.6 11.4 0.52 10.6 5.1 1.5 2 0 0 2 2 2 0 TCP family transcription factor VPS9 PF02204.13 ETO11205.1 - 3.5e-15 55.9 0.1 1.3e-14 54.0 0.0 2.0 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Secretin_N_2 PF07655.8 ETO11205.1 - 0.022 15.1 6.5 0.022 15.1 4.5 3.6 2 1 1 3 3 3 0 Secretin N-terminal domain Med21 PF11221.3 ETO11205.1 - 1.8 8.5 10.8 0.056 13.4 0.8 2.7 3 0 0 3 3 3 0 Subunit 21 of Mediator complex Cullin_binding PF03556.10 ETO11206.1 - 0.46 10.6 3.8 3.4 7.8 0.0 3.1 2 1 1 3 3 3 0 Cullin binding G-alpha PF00503.15 ETO11207.1 - 1.9e-64 217.7 4.7 2.4e-64 217.4 3.3 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO11207.1 - 1.4e-06 27.6 1.8 3.5e-06 26.3 1.2 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETO11207.1 - 0.00021 20.4 0.4 0.00072 18.7 0.3 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region TPR_2 PF07719.12 ETO11208.1 - 4.5e-08 32.4 3.4 0.0086 15.9 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO11208.1 - 5e-07 29.2 2.9 0.0028 17.2 0.0 4.3 3 2 1 4 4 4 2 TPR repeat TPR_1 PF00515.23 ETO11208.1 - 5.4e-07 28.9 0.4 0.0092 15.5 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO11208.1 - 0.00056 19.8 2.8 0.036 13.9 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO11208.1 - 0.0074 16.4 0.1 4.2 7.7 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO11208.1 - 0.018 14.8 1.7 8.9 6.3 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETO11208.1 - 0.03 14.6 0.2 16 5.9 0.0 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.1 ETO11208.1 - 0.054 13.6 0.1 0.31 11.1 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO11208.1 - 0.089 12.0 0.5 0.92 8.8 0.1 2.5 2 0 0 2 2 2 0 SHNi-TPR TPR_14 PF13428.1 ETO11208.1 - 0.095 13.3 0.7 59 4.7 0.1 4.2 3 2 2 5 5 5 0 Tetratricopeptide repeat YcbB PF08664.5 ETO11208.1 - 0.096 12.4 0.8 0.23 11.2 0.5 1.6 1 0 0 1 1 1 0 YcbB domain TPR_12 PF13424.1 ETO11209.1 - 5.4e-43 144.8 11.4 2.6e-20 72.1 1.3 3.6 2 1 3 5 5 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO11209.1 - 3.6e-24 84.1 21.5 4.1e-13 48.7 3.3 3.1 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETO11209.1 - 8.2e-16 56.8 19.1 7.6e-09 34.8 0.3 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO11209.1 - 3.1e-15 54.6 2.5 8.7e-06 25.1 0.0 4.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO11209.1 - 1.6e-14 52.5 12.2 3.9e-07 29.4 0.1 4.9 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO11209.1 - 5.7e-14 50.7 19.1 6e-06 25.6 0.7 5.0 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO11209.1 - 8.2e-14 51.0 0.0 2.6e-05 24.0 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat MIT PF04212.13 ETO11209.1 - 7.8e-09 35.3 1.3 0.0015 18.3 0.1 2.9 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 ETO11209.1 - 8.9e-06 25.8 0.8 0.28 11.7 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO11209.1 - 1.9e-05 24.5 6.9 0.022 14.9 0.1 3.4 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO11209.1 - 0.0088 16.5 0.0 11 7.0 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat DUF2225 PF09986.4 ETO11209.1 - 0.015 14.8 2.0 0.015 14.8 1.4 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Apc3 PF12895.2 ETO11209.1 - 0.018 15.1 5.3 0.082 13.0 3.3 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 ETO11209.1 - 0.027 15.1 0.1 0.25 12.0 0.0 2.4 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_3 PF07720.7 ETO11209.1 - 0.032 14.0 4.5 0.93 9.3 0.7 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat NSF PF02071.15 ETO11209.1 - 2.7 8.9 9.1 14 6.8 0.4 4.5 3 0 0 3 3 3 0 Aromatic-di-Alanine (AdAR) repeat TPR_11 PF13414.1 ETO11210.1 - 0.034 13.7 2.5 0.049 13.2 0.4 2.0 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.1 ETO11210.1 - 0.049 14.2 0.0 0.12 13.1 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETO11210.1 - 0.055 13.2 1.3 0.29 11.0 0.0 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETO11210.1 - 0.2 11.6 1.3 0.59 10.1 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat OATP PF03137.15 ETO11211.1 - 0.0058 14.7 0.1 0.0066 14.5 0.1 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family CAP_GLY PF01302.20 ETO11212.1 - 4.1e-15 55.2 0.7 8.8e-15 54.1 0.5 1.6 1 0 0 1 1 1 1 CAP-Gly domain Cytochrom_B558a PF05038.8 ETO11213.1 - 0.15 11.6 0.6 0.56 9.8 0.4 1.9 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Mucin PF01456.12 ETO11213.1 - 0.31 10.7 28.7 0.053 13.2 14.1 2.6 2 1 0 2 2 2 0 Mucin-like glycoprotein Kinesin PF00225.18 ETO11214.1 - 4e-17 61.9 4.1 1.1e-15 57.1 0.7 2.9 2 1 0 2 2 2 1 Kinesin motor domain RFXA_RFXANK_bdg PF15289.1 ETO11214.1 - 0.19 11.9 1.9 1.1 9.4 0.1 2.2 2 0 0 2 2 2 0 Regulatory factor X-associated C-terminal binding domain CK_II_beta PF01214.13 ETO11216.1 - 2.6e-10 40.1 0.1 3.8e-10 39.5 0.1 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Secretin_N_2 PF07655.8 ETO11216.1 - 0.65 10.4 4.2 0.86 10.0 2.9 1.1 1 0 0 1 1 1 0 Secretin N-terminal domain Lipl32 PF12103.3 ETO11218.1 - 0.11 11.9 1.5 0.19 11.1 0.1 1.9 2 0 0 2 2 2 0 Surface lipoprotein of Spirochaetales order Ras PF00071.17 ETO11219.1 - 0.042 13.2 0.1 0.065 12.6 0.1 1.5 1 1 0 1 1 1 0 Ras family zf-C4pol PF14260.1 ETO11220.1 - 3.6 7.6 10.2 0.22 11.5 1.3 2.7 2 1 1 3 3 3 0 C4-type zinc-finger of DNA polymerase delta MIF4G PF02854.14 ETO11222.1 - 1.7e-06 27.5 1.5 3.9e-06 26.4 0.9 1.7 1 1 0 1 1 1 1 MIF4G domain Polyoma_lg_T_C PF06431.6 ETO11223.1 - 0.07 11.7 1.0 0.11 11.0 0.7 1.3 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus DUF2890 PF11081.3 ETO11223.1 - 0.15 12.1 10.8 0.26 11.3 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) RXT2_N PF08595.6 ETO11223.1 - 0.54 10.0 7.4 2 8.1 5.2 1.9 1 1 0 1 1 1 0 RXT2-like, N-terminal Saw1 PF11561.3 ETO11223.1 - 0.69 9.2 5.9 1.2 8.4 4.1 1.4 1 0 0 1 1 1 0 Single strand annealing-weakened 1 Voldacs PF03517.8 ETO11223.1 - 3.1 7.6 7.9 7.1 6.4 5.5 1.6 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling DUF4611 PF15387.1 ETO11223.1 - 4 7.6 11.6 3.3 7.9 6.2 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4611) JAB PF01398.16 ETO11224.1 - 1.8e-17 63.0 0.2 5.2e-17 61.6 0.1 1.8 1 1 1 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 ETO11224.1 - 5e-05 22.8 0.0 8.8e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Mucin PF01456.12 ETO11224.1 - 2.2 8.0 22.3 3.7 7.3 15.5 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SOBP PF15279.1 ETO11226.1 - 3.1 8.1 7.0 3.9 7.7 4.9 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DUF3782 PF12644.2 ETO11226.1 - 7.2 6.4 8.2 17 5.2 5.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) DUF4502 PF14950.1 ETO11228.1 - 0.051 12.7 1.3 0.055 12.6 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4502) HSBP1 PF06825.7 ETO11228.1 - 0.056 13.0 0.1 0.14 11.7 0.1 1.7 1 0 0 1 1 1 0 Heat shock factor binding protein 1 CUE PF02845.11 ETO11228.1 - 0.062 12.8 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 CUE domain DnaG_DnaB_bind PF08278.6 ETO11228.1 - 0.1 12.8 3.0 0.19 11.9 0.3 2.1 1 1 1 2 2 2 0 DNA primase DnaG DnaB-binding HTH_8 PF02954.14 ETO11228.1 - 0.12 11.9 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Guanylate_kin PF00625.16 ETO11228.1 - 0.3 10.5 4.2 0.16 11.4 1.0 1.9 1 1 1 2 2 2 0 Guanylate kinase RhoGEF PF00621.15 ETO11229.1 - 0.00037 20.4 0.0 0.0007 19.5 0.0 1.5 1 1 0 1 1 1 1 RhoGEF domain Mucin PF01456.12 ETO11230.1 - 0.0016 18.2 26.7 0.0016 18.2 18.5 1.6 2 0 0 2 2 2 1 Mucin-like glycoprotein Sporozoite_P67 PF05642.6 ETO11230.1 - 0.29 8.9 10.3 0.28 8.9 7.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Dicty_REP PF05086.7 ETO11230.1 - 1.4 6.5 15.0 2 6.1 10.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mei5 PF10376.4 ETO11230.1 - 6.3 6.2 9.7 8.8 5.7 6.7 1.2 1 0 0 1 1 1 0 Double-strand recombination repair protein Helicase_C_3 PF13625.1 ETO11232.1 - 2.6e-11 43.3 0.0 1.2e-10 41.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RICTOR_V PF14668.1 ETO11233.1 - 0.82 9.6 5.0 3.1 7.8 0.7 2.4 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 DUF3439 PF11921.3 ETO11233.1 - 5.7 6.7 12.2 0.91 9.2 5.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF4059 PF13268.1 ETO11233.1 - 5.7 7.1 14.8 0.074 13.2 3.7 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4059) DUF485 PF04341.7 ETO11233.1 - 9.4 6.0 13.7 4.6 7.0 3.5 2.9 2 1 0 2 2 2 0 Protein of unknown function, DUF485 EF-hand_1 PF00036.27 ETO11234.1 - 0.00088 18.4 0.3 0.0032 16.6 0.1 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 ETO11234.1 - 0.0024 17.5 0.1 0.0087 15.8 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 ETO11234.1 - 0.017 15.2 1.1 0.07 13.2 0.1 2.4 2 1 0 2 2 2 0 EF-hand domain pair vMSA PF00695.14 ETO11234.1 - 0.083 12.0 5.1 0.12 11.5 3.6 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Trypan_PARP PF05887.6 ETO11234.1 - 4.8 6.9 15.1 5.6 6.7 6.3 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Corona_6B_7B PF03262.8 ETO11235.1 - 0.032 13.4 0.2 0.032 13.4 0.2 1.4 2 0 0 2 2 2 0 Coronavirus 6B/7B protein DEAD PF00270.24 ETO11236.1 - 5.4e-19 68.2 0.1 1.9e-18 66.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 ETO11236.1 - 0.0016 18.3 2.0 0.0058 16.4 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SLX9 PF15341.1 ETO11236.1 - 0.049 14.0 4.1 0.1 13.0 2.8 1.5 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 SecA_DEAD PF07517.9 ETO11236.1 - 0.056 12.7 1.0 0.11 11.7 0.7 1.6 1 1 0 1 1 1 0 SecA DEAD-like domain TLC PF03219.9 ETO11238.1 - 0.11 11.0 0.6 0.13 10.7 0.4 1.1 1 0 0 1 1 1 0 TLC ATP/ADP transporter DUF1216 PF06746.6 ETO11238.1 - 0.3 10.8 3.9 0.13 11.9 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1216) Rot1 PF10681.4 ETO11239.1 - 0.0084 15.4 0.1 0.0099 15.2 0.1 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Mab-21 PF03281.9 ETO11239.1 - 0.032 13.3 0.2 0.042 12.9 0.1 1.2 1 0 0 1 1 1 0 Mab-21 protein NIF PF03031.13 ETO11240.1 - 8.2e-35 119.8 0.1 1.4e-34 119.0 0.1 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 ETO11240.1 - 0.069 13.3 0.2 0.49 10.5 0.0 2.4 1 1 2 3 3 3 0 Haloacid dehalogenase-like hydrolase DUF244 PF03112.9 ETO11241.1 - 0.071 12.6 0.8 0.095 12.2 0.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF AP4E_app_platf PF14807.1 ETO11243.1 - 0.077 13.2 0.1 0.19 11.9 0.1 1.6 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform RNA_pol_3_Rpc31 PF11705.3 ETO11243.1 - 0.68 9.8 6.1 0.97 9.3 4.2 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NPR2 PF06218.6 ETO11244.1 - 3.8e-35 121.4 8.7 2.6e-33 115.3 6.1 2.4 1 1 0 1 1 1 1 Nitrogen permease regulator 2 GLE1 PF07817.8 ETO11245.1 - 0.37 9.6 6.5 0.29 10.0 0.6 2.3 2 0 0 2 2 2 0 GLE1-like protein SPX PF03105.14 ETO11245.1 - 0.67 9.6 10.6 0.25 11.0 4.4 2.1 2 0 0 2 2 2 0 SPX domain Mod_r PF07200.8 ETO11245.1 - 1.2 9.0 19.2 0.35 10.7 8.2 2.5 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF2407_C PF13373.1 ETO11245.1 - 3.6 7.4 10.6 1.9 8.3 2.8 2.7 3 0 0 3 3 3 0 DUF2407 C-terminal domain E1-E2_ATPase PF00122.15 ETO11246.1 - 2e-52 177.4 0.5 2e-52 177.4 0.3 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 ETO11246.1 - 2e-28 100.2 0.0 5.5e-28 98.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETO11246.1 - 3.2e-13 50.2 0.5 1.2e-12 48.4 0.3 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 ETO11246.1 - 0.085 12.4 2.9 0.11 12.0 0.2 2.5 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Nup84_Nup100 PF04121.8 ETO11247.1 - 0.014 13.1 1.5 0.018 12.7 1.0 1.1 1 0 0 1 1 1 0 Nuclear pore protein 84 / 107 DUF2303 PF10065.4 ETO11247.1 - 0.056 12.3 0.2 0.065 12.1 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2303) WD40 PF00400.27 ETO11248.1 - 0.2 11.6 7.6 22 5.1 0.2 4.4 4 1 0 4 4 4 0 WD domain, G-beta repeat FimP PF09766.4 ETO11251.1 - 0.02 14.0 0.4 0.025 13.6 0.3 1.2 1 0 0 1 1 1 0 Fms-interacting protein HSP20 PF00011.16 ETO11251.1 - 0.12 12.2 0.3 0.48 10.3 0.1 1.9 2 0 0 2 2 2 0 Hsp20/alpha crystallin family HopJ PF08888.6 ETO11251.1 - 0.58 10.1 5.7 0.71 9.8 0.1 2.4 2 0 0 2 2 2 0 HopJ type III effector protein Peroxin-3 PF04882.7 ETO11252.1 - 6.1e-08 31.8 1.1 8.1e-08 31.3 0.7 1.5 1 1 0 1 1 1 1 Peroxin-3 DUF912 PF06024.7 ETO11252.1 - 0.015 15.3 2.4 2.4 8.2 0.0 2.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PP2C_2 PF13672.1 ETO11252.1 - 0.055 12.8 1.5 0.077 12.3 0.2 1.7 2 0 0 2 2 2 0 Protein phosphatase 2C EphA2_TM PF14575.1 ETO11252.1 - 0.6 10.5 4.4 5.3 7.4 0.1 3.4 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF2956 PF11169.3 ETO11252.1 - 2.7 7.9 8.3 1.8 8.5 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2956) DivIC PF04977.10 ETO11253.1 - 0.00024 20.4 4.3 0.00024 20.4 3.0 5.5 5 0 0 5 5 5 2 Septum formation initiator K-box PF01486.12 ETO11253.1 - 0.036 13.8 1.1 0.036 13.8 0.8 5.8 4 2 2 6 6 6 0 K-box region DUF4140 PF13600.1 ETO11253.1 - 0.047 14.1 26.4 0.069 13.6 1.1 5.3 5 0 0 5 5 5 0 N-terminal domain of unknown function (DUF4140) TSC22 PF01166.13 ETO11253.1 - 0.057 13.3 16.0 3.1 7.8 0.8 4.2 4 0 0 4 4 4 0 TSC-22/dip/bun family IncA PF04156.9 ETO11253.1 - 0.14 11.7 45.7 0.063 12.8 15.5 4.0 3 1 0 3 3 3 0 IncA protein T2SF PF00482.18 ETO11253.1 - 0.15 11.9 0.9 0.51 10.2 0.6 2.0 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F ETRAMP PF09716.5 ETO11253.1 - 0.55 10.2 7.7 4.5 7.2 4.7 2.8 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Reo_sigmaC PF04582.7 ETO11253.1 - 0.93 8.6 9.9 2 7.4 1.0 2.9 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Strep_SA_rep PF06696.6 ETO11253.1 - 7.3 6.4 15.0 2.4 7.9 2.2 3.0 3 0 0 3 3 3 0 Streptococcal surface antigen repeat Carboxyl_trans PF01039.17 ETO11254.1 - 3.3e-138 461.1 0.1 5.8e-136 453.7 0.1 2.9 1 1 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 ETO11254.1 - 0.028 13.6 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 Malonate decarboxylase gamma subunit (MdcE) DUF3354 PF11834.3 ETO11255.1 - 0.11 12.1 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3354) TSKS PF15358.1 ETO11255.1 - 0.12 10.5 2.1 0.16 10.1 1.5 1.1 1 0 0 1 1 1 0 Testis-specific serine kinase substrate WD40 PF00400.27 ETO11257.1 - 1e-77 253.4 17.0 3e-13 49.0 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO11257.1 - 2.4e-10 39.1 7.2 0.0073 14.5 0.0 5.5 1 1 2 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO11257.1 - 1.6e-07 30.4 8.6 0.46 9.1 0.1 5.4 1 1 5 6 6 6 4 Nup133 N terminal like PD40 PF07676.7 ETO11257.1 - 6.3e-06 25.7 7.4 3.1 7.5 0.1 6.2 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO11257.1 - 1.2e-05 24.8 0.2 0.0026 17.2 0.0 2.8 1 1 0 3 3 3 1 PQQ-like domain Nbas_N PF15492.1 ETO11257.1 - 1.3e-05 24.4 1.8 0.0092 15.1 0.2 3.8 1 1 2 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 ETO11257.1 - 9.2e-05 21.6 1.4 2.9 7.3 0.0 4.5 4 0 0 4 4 4 1 Proteasome subunit A N-terminal signature DPPIV_N PF00930.16 ETO11257.1 - 0.00014 20.6 0.0 0.23 10.0 0.0 3.5 1 1 1 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Cytochrom_D1 PF02239.11 ETO11257.1 - 0.00073 17.9 0.1 0.73 8.0 0.0 2.8 1 1 2 3 3 3 2 Cytochrome D1 heme domain Resistin PF06954.6 ETO11257.1 - 0.0059 16.8 0.4 31 4.9 0.0 4.0 1 1 3 4 4 4 0 Resistin GH97_N PF14508.1 ETO11257.1 - 0.019 13.9 0.0 1.1 8.2 0.0 3.0 4 0 0 4 4 4 0 Glycosyl-hydrolase 97 N-terminal AlphaC_N PF08829.5 ETO11257.1 - 0.05 12.9 0.0 0.094 12.0 0.0 1.4 1 0 0 1 1 1 0 Alpha C protein N terminal TPR_12 PF13424.1 ETO11258.1 - 1.6e-40 136.9 15.3 8.5e-15 54.4 0.1 5.3 4 1 0 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.23 ETO11258.1 - 7.3e-25 85.5 33.3 7.1e-07 28.5 1.8 6.7 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.1 ETO11258.1 - 8.4e-23 79.5 0.0 2.1e-06 27.4 0.0 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO11258.1 - 3.7e-22 77.7 19.2 8.4e-08 31.7 1.0 4.5 3 1 2 5 5 5 5 TPR repeat TPR_2 PF07719.12 ETO11258.1 - 1.8e-21 74.2 25.3 0.00014 21.5 0.8 6.7 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.1 ETO11258.1 - 1.6e-19 68.0 6.9 9.1e-05 21.9 0.0 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO11258.1 - 5e-13 47.8 33.9 0.015 15.0 1.5 7.1 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.1 ETO11258.1 - 9.5e-08 31.6 4.0 1.6 9.1 0.4 6.7 6 1 0 6 6 6 1 Tetratricopeptide repeat Peptidase_C14 PF00656.17 ETO11258.1 - 7e-06 25.9 3.1 0.00016 21.4 2.2 2.5 1 1 0 1 1 1 1 Caspase domain TPR_16 PF13432.1 ETO11258.1 - 4.8e-05 23.9 0.2 0.21 12.3 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO11258.1 - 0.00023 21.5 0.0 17 6.3 0.0 5.1 4 1 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO11258.1 - 0.0013 19.0 8.6 9.8 6.8 0.3 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO11258.1 - 0.002 18.4 0.7 0.24 11.7 0.0 3.7 3 1 2 5 5 5 2 Tetratricopeptide repeat Sel1 PF08238.7 ETO11258.1 - 2.2 9.0 12.6 1 10.0 0.5 4.0 4 0 0 4 4 4 0 Sel1 repeat NAGLU PF05089.7 ETO11259.1 - 2.1e-68 230.5 0.4 3.2e-68 229.9 0.3 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.2 ETO11259.1 - 1.5e-65 221.2 0.2 2e-65 220.8 0.1 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain RWD PF05773.17 ETO11260.1 - 2e-21 75.9 1.2 2e-21 75.9 0.9 1.8 2 0 0 2 2 2 1 RWD domain UQ_con PF00179.21 ETO11260.1 - 0.056 12.8 0.2 0.056 12.8 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-conjugating enzyme CPSF100_C PF13299.1 ETO11260.1 - 4.1 7.5 9.6 10 6.2 6.7 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Pkinase PF00069.20 ETO11261.1 - 2.2e-35 122.0 9.7 4.3e-35 121.1 0.4 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO11261.1 - 1.2e-19 70.4 1.3 1.7e-17 63.3 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 ETO11261.1 - 0.0024 16.9 0.0 0.0041 16.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_Ag35 PF03286.9 ETO11261.1 - 0.0089 15.5 1.3 0.016 14.7 0.9 1.3 1 0 0 1 1 1 1 Pox virus Ag35 surface protein MIT PF04212.13 ETO11262.1 - 8.5e-17 60.8 0.5 1.3e-16 60.1 0.2 1.5 1 1 0 1 1 1 1 MIT (microtubule interacting and transport) domain BLVR PF06375.6 ETO11262.1 - 0.47 10.2 6.5 0.82 9.4 4.5 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) AAA PF00004.24 ETO11263.1 - 2e-17 63.6 0.0 2.7e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 ETO11263.1 - 3e-06 26.2 0.0 3.1e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 ETO11263.1 - 6.4e-06 25.6 0.0 7.9e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 ETO11263.1 - 1.2e-05 26.0 0.0 1.7e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETO11263.1 - 2.2e-05 24.5 0.0 2.2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 ETO11263.1 - 0.00016 21.8 0.0 0.00021 21.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 ETO11263.1 - 0.00019 21.5 0.0 0.00033 20.7 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.1 ETO11263.1 - 0.00019 21.3 0.0 0.00025 20.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 ETO11263.1 - 0.00026 20.0 0.0 0.00028 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 ETO11263.1 - 0.00036 20.2 0.0 0.00052 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 ETO11263.1 - 0.00046 19.3 0.0 0.00046 19.3 0.0 1.1 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 ETO11263.1 - 0.00084 19.6 0.0 0.001 19.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain Torsin PF06309.6 ETO11263.1 - 0.0015 18.4 0.0 0.0017 18.2 0.0 1.1 1 0 0 1 1 1 1 Torsin Arch_ATPase PF01637.13 ETO11263.1 - 0.0019 17.9 0.0 0.0035 17.0 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase Mg_chelatase PF01078.16 ETO11263.1 - 0.003 16.7 0.0 0.0045 16.1 0.0 1.3 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.11 ETO11263.1 - 0.0044 16.2 0.0 0.0054 15.9 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein Parvo_NS1 PF01057.12 ETO11263.1 - 0.0049 15.7 0.0 0.0063 15.4 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_19 PF13245.1 ETO11263.1 - 0.0049 16.5 0.0 0.0064 16.2 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain NB-ARC PF00931.17 ETO11263.1 - 0.0063 15.4 0.0 0.0075 15.1 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_24 PF13479.1 ETO11263.1 - 0.0064 16.0 0.0 0.0078 15.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 ETO11263.1 - 0.011 15.4 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.1 ETO11263.1 - 0.012 15.0 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 ETO11263.1 - 0.013 14.5 0.1 0.015 14.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 ETO11263.1 - 0.014 14.5 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.1 ETO11263.1 - 0.015 15.1 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 ETO11263.1 - 0.016 15.1 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain MCM PF00493.18 ETO11263.1 - 0.017 13.9 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 MCM2/3/5 family Sigma54_activat PF00158.21 ETO11263.1 - 0.018 14.5 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain Guanylate_kin PF00625.16 ETO11263.1 - 0.028 13.8 0.0 0.047 13.1 0.0 1.4 1 1 0 1 1 1 0 Guanylate kinase ResIII PF04851.10 ETO11263.1 - 0.032 14.0 0.0 0.032 14.0 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.1 ETO11263.1 - 0.033 14.2 0.0 0.055 13.5 0.0 1.5 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.1 ETO11263.1 - 0.077 12.5 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 ETO11263.1 - 0.097 11.6 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain ABC_tran PF00005.22 ETO11263.1 - 0.097 12.9 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 ABC transporter PPV_E1_C PF00519.12 ETO11263.1 - 0.11 11.0 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase Bac_DnaA PF00308.13 ETO11263.1 - 0.11 12.0 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial dnaA protein AAA PF00004.24 ETO11264.1 - 3.4e-19 69.3 0.0 4.2e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF4604 PF15377.1 ETO11265.1 - 1.2 9.3 38.2 1.4 9.0 26.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) CDC45 PF02724.9 ETO11265.1 - 7.4 4.4 27.7 8 4.3 19.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Tau95 PF09734.4 ETO11266.1 - 5.3e-10 39.1 0.8 5.3e-10 39.1 0.5 2.2 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit DUF1111 PF06537.6 ETO11266.1 - 0.013 13.8 0.3 0.015 13.6 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1111) FimP PF09766.4 ETO11267.1 - 0.00088 18.4 6.2 0.00088 18.4 4.3 2.1 2 0 0 2 2 2 1 Fms-interacting protein SCIMP PF15050.1 ETO11267.1 - 0.0069 16.2 0.1 0.0069 16.2 0.1 1.9 2 0 0 2 2 2 1 SCIMP protein HSP90 PF00183.13 ETO11267.1 - 0.007 14.8 8.8 0.011 14.1 6.1 1.3 1 0 0 1 1 1 1 Hsp90 protein CDC45 PF02724.9 ETO11267.1 - 0.13 10.2 7.4 0.22 9.5 5.1 1.4 1 0 0 1 1 1 0 CDC45-like protein Toprim PF01751.17 ETO11268.1 - 2.2 8.3 9.0 0.025 14.5 1.0 1.7 2 1 0 2 2 2 0 Toprim domain SPT6_acidic PF14632.1 ETO11268.1 - 5.5 7.2 9.4 1.9 8.6 2.1 2.5 2 0 0 2 2 2 0 Acidic N-terminal SPT6 MMtag PF10159.4 ETO11268.1 - 6.4 6.9 8.5 2.1 8.4 2.3 2.6 2 1 0 2 2 2 0 Kinase phosphorylation protein DUF4604 PF15377.1 ETO11269.1 - 0.21 11.8 8.8 0.25 11.5 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DUF4512 PF14975.1 ETO11269.1 - 0.76 10.6 7.0 0.97 10.2 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) RIX1 PF08167.7 ETO11270.1 - 0.064 12.9 1.6 0.28 10.8 0.2 2.2 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis LAT PF15234.1 ETO11270.1 - 5.4 6.4 8.2 11 5.4 5.7 1.4 1 0 0 1 1 1 0 Linker for activation of T-cells DUF4042 PF13251.1 ETO11271.1 - 1.8e-18 66.6 1.9 2.9e-09 36.6 0.1 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF4042) HEAT PF02985.17 ETO11271.1 - 0.00059 19.7 0.8 1.1 9.5 0.0 3.9 4 0 0 4 4 4 2 HEAT repeat DUF4131 PF13567.1 ETO11271.1 - 0.44 9.9 6.3 0.9 8.9 4.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Ycf1 PF05758.7 ETO11272.1 - 0.013 13.2 2.5 0.012 13.3 1.7 1.2 1 0 0 1 1 1 0 Ycf1 MIP-T3 PF10243.4 ETO11272.1 - 0.027 12.9 22.3 0.0055 15.2 13.0 1.7 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 FLO_LFY PF01698.11 ETO11272.1 - 0.055 12.3 8.8 0.11 11.3 6.1 1.5 1 0 0 1 1 1 0 Floricaula / Leafy protein Tim54 PF11711.3 ETO11272.1 - 0.067 11.7 6.4 0.094 11.2 4.4 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.9 ETO11272.1 - 0.079 10.9 13.1 0.13 10.2 9.1 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 ETO11272.1 - 0.083 12.2 20.1 0.17 11.2 13.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) GAGA_bind PF06217.7 ETO11272.1 - 0.41 10.5 10.4 0.72 9.7 7.2 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family U79_P34 PF03064.11 ETO11272.1 - 1.7 8.0 20.6 3.9 6.9 14.2 1.6 1 0 0 1 1 1 0 HSV U79 / HCMV P34 NPR3 PF03666.8 ETO11272.1 - 1.9 6.9 10.4 3.3 6.1 7.2 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RRN3 PF05327.6 ETO11272.1 - 2.5 6.1 6.3 3.6 5.5 4.4 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 AAA_11 PF13086.1 ETO11272.1 - 3.5 7.1 8.7 3.9 6.9 4.5 1.9 2 0 0 2 2 2 0 AAA domain AIF_C PF14721.1 ETO11272.1 - 5.2 7.3 7.8 13 5.9 5.4 1.7 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term YqfQ PF14181.1 ETO11272.1 - 5.8 6.9 14.8 16 5.5 10.3 1.8 1 0 0 1 1 1 0 YqfQ-like protein Sec62 PF03839.11 ETO11272.1 - 6.8 6.0 17.9 12 5.2 12.4 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Zip PF02535.17 ETO11272.1 - 8.7 5.2 6.3 15 4.4 4.3 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter MAGUK_N_PEST PF10608.4 ETO11273.1 - 0.0046 17.3 0.0 0.0056 17.0 0.0 1.2 1 0 0 1 1 1 1 Polyubiquitination (PEST) N-terminal domain of MAGUK FlhC PF05280.6 ETO11273.1 - 0.038 13.4 0.1 0.051 13.0 0.0 1.2 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) DUF2202 PF09968.4 ETO11273.1 - 0.08 12.6 0.3 0.11 12.1 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein domain (DUF2202) UCH PF00443.24 ETO11274.1 - 1.3e-14 54.0 7.2 1.7e-14 53.5 5.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO11274.1 - 7.6e-07 28.8 3.9 9.6e-07 28.5 2.7 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PUB PF09409.5 ETO11276.1 - 8.6e-05 22.2 1.4 8.6e-05 22.2 1.0 3.1 2 2 1 3 3 3 1 PUB domain PCI PF01399.22 ETO11276.1 - 1.2 9.4 7.6 1.4 9.3 3.7 2.2 1 1 1 2 2 2 0 PCI domain LAGLIDADG_1 PF00961.14 ETO11276.1 - 6.7 7.3 12.5 1.2 9.7 3.9 2.5 2 1 1 3 3 3 0 LAGLIDADG endonuclease ART PF01129.13 ETO11277.1 - 0.00018 20.7 0.0 0.00032 19.8 0.0 1.4 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase LRR_4 PF12799.2 ETO11278.1 - 6.5e-32 108.6 40.4 6e-08 32.1 0.3 8.3 5 2 2 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETO11278.1 - 6.6e-29 95.4 38.8 0.096 12.7 0.0 13.1 13 0 0 13 13 13 13 Leucine Rich Repeat LRR_8 PF13855.1 ETO11278.1 - 6.3e-23 80.2 39.2 2e-05 24.2 0.3 6.1 4 2 3 7 7 7 6 Leucine rich repeat LRR_6 PF13516.1 ETO11278.1 - 6.6e-20 68.9 33.9 0.064 13.3 0.2 12.7 13 0 0 13 13 13 9 Leucine Rich repeat LRR_7 PF13504.1 ETO11278.1 - 1.1e-14 51.9 36.9 0.29 11.4 0.0 12.7 13 0 0 13 13 13 6 Leucine rich repeat LRR_1 PF00560.28 ETO11279.1 - 3.5e-06 26.3 7.4 0.42 10.8 0.0 4.1 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_4 PF12799.2 ETO11279.1 - 0.00021 20.8 9.2 0.00038 20.0 1.2 2.6 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO11279.1 - 0.078 12.7 7.4 0.096 12.4 3.1 2.1 2 0 0 2 2 2 0 Leucine rich repeat LRR_7 PF13504.1 ETO11279.1 - 0.11 12.7 9.3 5.3 7.6 0.1 4.2 3 1 0 3 3 3 0 Leucine rich repeat FAD_binding_8 PF08022.7 ETO11280.1 - 1.6e-13 50.4 0.0 2.4e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.19 ETO11280.1 - 0.0013 18.7 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Ferric_reduct PF01794.14 ETO11280.1 - 0.0052 16.8 5.9 0.0052 16.8 4.1 1.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FKBP_C PF00254.23 ETO11283.1 - 3.2e-05 23.8 0.0 0.00029 20.7 0.0 2.5 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase WH1 PF00568.18 ETO11283.1 - 0.00019 21.1 0.0 0.00043 19.9 0.0 1.5 1 0 0 1 1 1 1 WH1 domain Josephin PF02099.12 ETO11284.1 - 2.5e-08 33.6 0.3 1e-07 31.7 0.2 2.1 1 1 0 1 1 1 1 Josephin UBX PF00789.15 ETO11284.1 - 1.1e-07 31.7 0.0 2.4e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 UBX domain UIM PF02809.15 ETO11284.1 - 7.9e-05 21.9 12.2 0.36 10.5 2.1 3.4 3 0 0 3 3 3 3 Ubiquitin interaction motif tRNA-synt_His PF13393.1 ETO11285.1 - 3.5e-10 39.4 0.0 1.5e-09 37.3 0.0 2.0 1 1 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon2 PF12745.2 ETO11285.1 - 0.0024 17.0 0.1 0.005 16.0 0.1 1.4 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs FAT PF02259.18 ETO11286.1 - 2.4e-07 30.0 0.8 4.7e-07 29.1 0.6 1.5 1 0 0 1 1 1 1 FAT domain DUF2069 PF09842.4 ETO11288.1 - 0.16 11.9 0.3 0.26 11.2 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2069) DUF912 PF06024.7 ETO11288.1 - 2.3 8.3 7.7 8.1 6.5 5.3 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) zf-C3HC PF07967.8 ETO11290.1 - 0.0051 16.5 1.0 0.0051 16.5 0.7 3.6 4 0 0 4 4 4 1 C3HC zinc finger-like Pkinase PF00069.20 ETO11291.1 - 1.9e-13 50.2 0.1 2.3e-13 49.8 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO11291.1 - 0.00041 19.5 0.1 0.00048 19.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 ETO11292.1 - 1.6e-17 63.4 0.0 1.9e-17 63.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO11292.1 - 0.001 18.2 0.0 0.0015 17.6 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Y_Y_Y PF07495.8 ETO11292.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Y_Y_Y domain Kinase-like PF14531.1 ETO11292.1 - 0.13 11.1 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like adh_short PF00106.20 ETO11293.1 - 5.8e-22 78.3 0.0 6.4e-14 52.2 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 ETO11293.1 - 1.6e-06 28.0 0.0 2.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETO11293.1 - 0.00013 21.7 0.0 0.00028 20.6 0.0 1.5 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 ETO11293.1 - 0.027 13.7 0.1 0.039 13.1 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family Saccharop_dh PF03435.13 ETO11293.1 - 0.07 12.1 0.2 0.098 11.6 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase SpoVIF PF14069.1 ETO11293.1 - 0.078 12.7 1.1 0.39 10.4 0.0 2.1 2 0 0 2 2 2 0 Stage VI sporulation protein F DUF99 PF01949.11 ETO11293.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF99 TPR_11 PF13414.1 ETO11294.1 - 4e-28 96.8 9.1 7.7e-09 35.0 0.0 4.5 3 1 2 5 5 5 5 TPR repeat TPR_8 PF13181.1 ETO11294.1 - 1.2e-22 77.9 7.3 0.00014 21.3 0.1 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETO11294.1 - 9.4e-22 75.1 5.1 0.00027 20.6 0.2 6.7 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 ETO11294.1 - 9.3e-21 73.5 8.0 0.00032 20.5 0.0 5.1 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO11294.1 - 8.6e-20 69.4 16.9 6.8e-05 22.3 0.5 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO11294.1 - 3.7e-16 59.2 0.0 2.7e-05 24.7 0.0 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO11294.1 - 2e-13 49.6 0.0 0.0013 19.1 0.0 5.7 2 2 4 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO11294.1 - 2.1e-09 37.6 0.0 0.015 15.6 0.0 4.1 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 ETO11294.1 - 2.4e-09 36.9 0.0 0.0082 15.9 0.0 3.9 2 2 2 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO11294.1 - 1.2e-08 34.9 14.9 8.5e-06 25.8 1.4 4.0 2 2 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETO11294.1 - 1.4e-08 34.6 2.8 5.4 7.7 0.0 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO11294.1 - 2.4e-08 33.5 9.8 2.5e-05 24.1 0.1 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO11294.1 - 1.3e-06 27.7 7.1 0.86 9.5 0.0 6.2 6 1 0 6 6 6 2 Tetratricopeptide repeat SNAP PF14938.1 ETO11294.1 - 0.00014 21.1 1.4 0.0011 18.1 0.0 2.5 3 0 0 3 3 3 1 Soluble NSF attachment protein, SNAP Clathrin PF00637.15 ETO11294.1 - 0.13 11.8 2.9 0.46 10.0 0.9 2.6 1 1 1 2 2 2 0 Region in Clathrin and VPS MIT PF04212.13 ETO11294.1 - 0.41 10.5 0.1 0.41 10.5 0.1 3.9 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain ADK PF00406.17 ETO11296.1 - 6.6e-83 276.0 0.0 4.8e-49 166.1 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 ETO11296.1 - 3.8e-31 106.4 0.3 6.2e-15 54.5 0.1 2.7 2 0 0 2 2 2 2 Adenylate kinase, active site lid AAA_17 PF13207.1 ETO11296.1 - 5e-07 30.5 0.1 2.5e-06 28.2 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 ETO11296.1 - 0.0012 18.7 0.0 0.0061 16.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain NMO PF03060.10 ETO11297.1 - 1.4e-34 119.7 1.6 2e-31 109.3 0.1 2.0 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.20 ETO11297.1 - 0.00016 20.7 0.0 0.00046 19.1 0.0 1.7 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NanE PF04131.9 ETO11297.1 - 0.011 14.6 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase APO_RNA-bind PF05634.6 ETO11297.1 - 0.022 13.9 0.3 0.036 13.2 0.2 1.3 1 0 0 1 1 1 0 APO RNA-binding NMO PF03060.10 ETO11298.1 - 6e-15 55.2 0.1 6.8e-15 55.0 0.0 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase DUF1902 PF08972.6 ETO11298.1 - 0.013 14.9 0.0 0.029 13.9 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1902) Endotoxin_N PF03945.9 ETO11298.1 - 0.099 12.0 0.3 0.84 8.9 0.0 2.0 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain DUF1870 PF08965.5 ETO11299.1 - 0.0084 15.7 0.4 0.028 14.0 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1870) PDCD2_C PF04194.8 ETO11299.1 - 1.1 8.7 8.9 0.17 11.4 1.7 2.3 2 0 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain IQ PF00612.22 ETO11300.1 - 5.6e-06 25.5 0.0 1.2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif SAP PF02037.22 ETO11302.1 - 0.016 14.6 0.0 0.53 9.8 0.0 2.6 2 0 0 2 2 2 0 SAP domain UAA PF08449.6 ETO11303.1 - 7.2e-13 48.1 8.0 8.4e-13 47.9 2.8 1.9 1 1 1 2 2 2 1 UAA transporter family Baculo_11_kDa PF06143.6 ETO11303.1 - 0.00051 19.3 2.4 0.0011 18.2 1.6 1.6 1 0 0 1 1 1 1 Baculovirus 11 kDa family DUF2659 PF10858.3 ETO11303.1 - 0.0087 15.4 6.7 0.014 14.7 4.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2659) TMEM154 PF15102.1 ETO11303.1 - 0.01 15.5 0.7 0.019 14.6 0.5 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF929 PF06053.6 ETO11303.1 - 0.011 14.7 2.3 0.017 14.1 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF929) DUF2500 PF10694.4 ETO11303.1 - 0.016 15.1 0.8 0.03 14.3 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) EphA2_TM PF14575.1 ETO11303.1 - 0.017 15.5 0.5 0.035 14.4 0.1 1.8 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain Chordopox_A13L PF05961.6 ETO11303.1 - 0.02 14.8 6.8 0.046 13.6 4.7 1.6 1 0 0 1 1 1 0 Chordopoxvirus A13L protein ODV-E18 PF10717.4 ETO11303.1 - 0.023 14.1 7.7 0.023 14.1 5.3 1.8 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 OppC_N PF12911.2 ETO11303.1 - 0.027 13.8 3.2 0.027 13.8 2.2 2.6 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C tRNA_anti-like PF12869.2 ETO11303.1 - 0.027 13.9 0.2 0.053 13.0 0.1 1.5 1 0 0 1 1 1 0 tRNA_anti-like RSN1_TM PF13967.1 ETO11303.1 - 0.035 13.6 2.0 0.069 12.7 1.4 1.5 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport DUF3357 PF11837.3 ETO11303.1 - 0.085 12.7 0.3 0.27 11.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) TarH PF02203.10 ETO11303.1 - 0.18 11.6 0.2 0.28 11.0 0.2 1.3 1 0 0 1 1 1 0 Tar ligand binding domain homologue ASFV_J13L PF05568.6 ETO11303.1 - 0.18 11.3 2.4 0.34 10.4 1.6 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein ETRAMP PF09716.5 ETO11303.1 - 0.19 11.6 1.7 0.72 9.8 1.2 2.0 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Sigma_reg_N PF13800.1 ETO11303.1 - 0.35 10.9 10.1 0.095 12.7 4.5 1.9 2 0 0 2 2 1 0 Sigma factor regulator N-terminal HN PF00423.14 ETO11303.1 - 0.54 8.4 7.2 0.67 8.1 5.0 1.1 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase ATP-synt_8 PF00895.15 ETO11303.1 - 0.86 9.8 9.3 0.13 12.4 2.1 2.5 2 0 0 2 2 2 0 ATP synthase protein 8 DUF3139 PF11337.3 ETO11303.1 - 1.3 9.3 7.6 0.42 10.9 2.9 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF3139) Baculo_VP91_N PF08475.5 ETO11303.1 - 1.8 7.9 5.6 2.8 7.2 3.8 1.2 1 0 0 1 1 1 0 Viral capsid protein 91 N-terminal COX2_TM PF02790.10 ETO11303.1 - 4.6 7.2 10.6 0.83 9.6 2.1 2.8 2 1 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain DUF3397 PF11877.3 ETO11303.1 - 6 6.9 11.7 0.8 9.7 0.7 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3397) DUF443 PF04276.7 ETO11303.1 - 8.1 5.8 17.8 0.44 9.9 8.1 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF443) RabGAP-TBC PF00566.13 ETO11304.1 - 0.046 13.2 0.8 0.046 13.2 0.5 1.7 2 0 0 2 2 2 0 Rab-GTPase-TBC domain RabGAP-TBC PF00566.13 ETO11305.1 - 1.6e-22 80.0 0.8 1.8e-22 79.9 0.5 1.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rhodanese PF00581.15 ETO11306.1 - 1.6e-05 25.2 0.0 3.6e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Tubulin PF00091.20 ETO11308.1 - 3e-20 72.9 0.1 4.2e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FimP PF09766.4 ETO11309.1 - 0.15 11.1 4.3 0.15 11.1 3.0 1.1 1 0 0 1 1 1 0 Fms-interacting protein Nitr_red_assoc PF09655.5 ETO11310.1 - 0.059 13.7 0.0 0.092 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) AAA PF00004.24 ETO11311.1 - 7.2e-08 32.7 0.0 9e-05 22.6 0.0 2.8 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETO11311.1 - 8e-07 28.8 0.0 0.00064 19.4 0.0 3.2 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETO11311.1 - 2.7e-06 27.5 0.1 0.0055 16.8 0.1 2.8 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 ETO11311.1 - 3.5e-05 23.0 0.0 0.0001 21.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 ETO11311.1 - 5.9e-05 23.1 0.0 0.0034 17.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 ETO11311.1 - 9.8e-05 22.6 0.0 0.00054 20.2 0.0 2.2 3 0 0 3 3 2 1 ABC transporter AAA_14 PF13173.1 ETO11311.1 - 0.00011 22.1 0.0 0.00038 20.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 ETO11311.1 - 0.00026 21.0 0.0 0.024 14.6 0.0 3.2 3 0 0 3 3 3 1 Sigma-54 interaction domain PduV-EutP PF10662.4 ETO11311.1 - 0.00045 19.7 0.0 0.0048 16.3 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MCM PF00493.18 ETO11311.1 - 0.0015 17.3 0.6 0.11 11.2 0.0 2.7 3 0 0 3 3 3 1 MCM2/3/5 family DUF815 PF05673.8 ETO11311.1 - 0.0018 17.2 0.0 0.0042 16.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 ETO11311.1 - 0.0057 16.3 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase RNA_helicase PF00910.17 ETO11311.1 - 0.0081 16.3 0.1 0.9 9.7 0.0 3.6 4 0 0 4 4 4 1 RNA helicase Sigma54_activat PF00158.21 ETO11311.1 - 0.012 15.0 0.0 0.67 9.4 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain Bac_DnaA PF00308.13 ETO11311.1 - 0.025 14.2 0.0 0.06 12.9 0.0 1.7 1 0 0 1 1 1 0 Bacterial dnaA protein Miro PF08477.8 ETO11311.1 - 0.025 15.0 0.3 0.11 13.0 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein AAA_2 PF07724.9 ETO11311.1 - 0.034 14.0 0.0 0.089 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Viral_helicase1 PF01443.13 ETO11311.1 - 0.037 13.5 0.0 0.072 12.5 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.7 ETO11311.1 - 0.057 13.0 0.1 0.27 10.8 0.1 2.1 2 0 0 2 2 2 0 NACHT domain T2SE PF00437.15 ETO11311.1 - 0.058 12.2 0.2 0.35 9.7 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein IstB_IS21 PF01695.12 ETO11311.1 - 0.063 12.6 0.0 0.74 9.2 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 ETO11311.1 - 0.073 12.2 0.0 2.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 ETO11311.1 - 0.078 13.2 0.0 0.33 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 ETO11311.1 - 0.087 12.4 0.0 0.27 10.8 0.0 1.8 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 ETO11311.1 - 0.1 13.4 0.1 0.41 11.4 0.0 2.1 2 1 0 2 2 1 0 AAA domain AAA_19 PF13245.1 ETO11311.1 - 0.13 12.0 0.0 11 5.8 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_23 PF13476.1 ETO11311.1 - 0.32 11.3 0.1 0.32 11.3 0.1 2.7 2 2 1 3 3 3 0 AAA domain TAFII28 PF04719.9 ETO11314.1 - 0.0079 15.9 0.3 0.021 14.5 0.2 1.7 1 0 0 1 1 1 1 hTAFII28-like protein conserved region LPP PF04728.8 ETO11314.1 - 0.017 14.8 2.3 1.1 9.0 1.6 2.8 2 1 0 2 2 2 0 Lipoprotein leucine-zipper Syntaxin PF00804.20 ETO11314.1 - 0.021 14.9 3.1 0.051 13.7 0.5 2.4 2 0 0 2 2 2 0 Syntaxin DUF4208 PF13907.1 ETO11314.1 - 0.047 13.9 4.0 0.15 12.3 2.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) Eaf7 PF07904.8 ETO11314.1 - 0.28 11.1 2.7 0.47 10.4 0.3 2.3 2 0 0 2 2 2 0 Chromatin modification-related protein EAF7 DUF948 PF06103.6 ETO11314.1 - 4.1 7.3 9.2 1.5 8.7 2.8 2.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) tRNA_bind PF01588.15 ETO11316.1 - 1e-25 89.3 0.0 1.3e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Putative tRNA binding domain GED PF02212.13 ETO11318.1 - 0.028 14.3 1.8 0.11 12.4 1.0 2.2 2 1 0 2 2 2 0 Dynamin GTPase effector domain AAA_13 PF13166.1 ETO11318.1 - 0.032 12.7 10.9 0.034 12.6 7.6 1.0 1 0 0 1 1 1 0 AAA domain Op_neuropeptide PF08035.6 ETO11318.1 - 0.073 12.6 1.1 0.3 10.6 0.0 2.5 3 0 0 3 3 3 0 Opioids neuropeptide Tom5 PF10642.4 ETO11318.1 - 0.14 11.8 0.3 21 4.8 0.7 2.3 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Flu_B_M2 PF04772.7 ETO11318.1 - 0.7 9.9 4.3 0.33 11.0 0.4 2.0 1 1 1 2 2 2 0 Influenza B matrix protein 2 (BM2) IncA PF04156.9 ETO11318.1 - 2.4 7.7 7.6 1.7 8.1 1.5 2.0 2 0 0 2 2 2 0 IncA protein DUF2146 PF10220.4 ETO11319.1 - 0.019 12.9 6.6 0.021 12.8 4.6 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) DUF936 PF06075.7 ETO11319.1 - 0.12 11.2 12.5 0.13 11.1 8.7 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Herpes_DNAp_acc PF04929.7 ETO11319.1 - 5.7 5.8 12.8 6.9 5.5 8.9 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor TPR_11 PF13414.1 ETO11320.1 - 3.7e-11 42.5 2.0 3.1e-09 36.3 0.1 2.3 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETO11320.1 - 1.1e-09 37.4 3.1 2.1e-05 23.9 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO11320.1 - 1.3e-09 37.2 2.9 0.00031 20.4 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO11320.1 - 0.009 16.6 0.1 0.051 14.2 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO11320.1 - 0.015 15.4 1.0 0.036 14.2 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETO11320.1 - 0.029 14.2 2.4 0.18 11.7 0.4 2.3 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETO11320.1 - 0.068 12.9 0.5 0.37 10.6 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3488 PF11992.3 ETO11320.1 - 0.17 10.4 1.0 0.25 9.9 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) Otopetrin PF03189.8 ETO11320.1 - 2.8 6.8 10.9 0.48 9.3 0.0 2.4 2 1 0 2 2 2 0 Otopetrin Sec7 PF01369.15 ETO11321.1 - 4.4e-56 189.5 0.4 1.3e-55 188.0 0.3 1.8 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 ETO11321.1 - 2.8e-22 78.9 10.9 2.3e-13 49.9 0.3 3.0 1 1 1 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF3641 PF12345.3 ETO11321.1 - 0.0089 15.8 0.6 0.053 13.3 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3641) DUF3377 PF11857.3 ETO11322.1 - 2.5 7.7 4.9 0.5 10.0 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) DUF1981 PF09324.5 ETO11323.1 - 3.4e-09 36.0 2.3 2.9e-07 29.9 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF1981) PHTB1_N PF14727.1 ETO11324.1 - 0.0017 17.3 0.7 0.051 12.5 0.1 2.0 1 1 1 2 2 2 2 PTHB1 N-terminus Kelch_6 PF13964.1 ETO11324.1 - 0.008 16.3 0.3 0.25 11.6 0.1 2.6 2 1 1 3 3 3 1 Kelch motif DUF4459 PF14673.1 ETO11324.1 - 0.017 14.8 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4459) IBR PF01485.16 ETO11325.1 - 0.0012 18.7 14.0 0.0012 18.7 9.7 3.7 2 2 1 4 4 4 1 IBR domain Rad60-SLD PF11976.3 ETO11325.1 - 0.0015 18.1 0.1 0.0031 17.1 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 ETO11325.1 - 0.0036 16.6 0.0 0.0076 15.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family zf-C3HC4_2 PF13923.1 ETO11325.1 - 0.016 15.2 5.0 0.016 15.2 3.5 4.1 5 0 0 5 5 5 0 Zinc finger, C3HC4 type (RING finger) Flagellin_IN PF07196.8 ETO11325.1 - 0.064 13.2 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Flagellin hook IN motif DinB PF05163.7 ETO11326.1 - 4.8e-05 23.1 0.6 0.00016 21.4 0.2 1.9 1 1 1 2 2 2 1 DinB family PHA_synth_III_E PF09712.5 ETO11326.1 - 0.04 13.3 0.1 0.056 12.8 0.1 1.2 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) DinB_2 PF12867.2 ETO11326.1 - 0.064 13.5 0.0 0.081 13.2 0.0 1.2 1 0 0 1 1 1 0 DinB superfamily DIM1 PF02966.11 ETO11326.1 - 0.26 10.7 3.0 3.1 7.3 0.3 2.3 2 0 0 2 2 2 0 Mitosis protein DIM1 WD40 PF00400.27 ETO11327.1 - 2.2e-33 112.9 7.5 1e-10 41.0 0.7 4.4 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO11327.1 - 1.2e-08 33.6 2.1 0.00034 18.8 0.3 3.0 2 1 1 3 3 3 3 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO11327.1 - 0.019 14.3 2.1 0.067 12.5 1.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4221) Imm21 PF15569.1 ETO11327.1 - 0.11 12.2 1.6 0.14 11.9 0.1 1.8 2 0 0 2 2 2 0 Immunity protein 21 DUF1796 PF08795.5 ETO11328.1 - 0.013 15.0 1.2 0.013 15.0 0.8 1.9 1 1 1 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) PspB PF06667.7 ETO11328.1 - 0.65 9.9 3.2 2.5 8.0 2.1 2.2 1 1 0 1 1 1 0 Phage shock protein B DUF4337 PF14235.1 ETO11328.1 - 8.3 6.2 7.3 1.3 8.8 2.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) HELP PF03451.9 ETO11329.1 - 0.031 13.7 0.2 0.078 12.5 0.1 1.7 1 1 1 2 2 2 0 HELP motif PEMT PF04191.8 ETO11330.1 - 0.068 13.2 0.3 0.1 12.7 0.2 1.3 1 0 0 1 1 1 0 Phospholipid methyltransferase Tmemb_cc2 PF10267.4 ETO11331.1 - 5.8 5.3 5.7 9.3 4.7 3.9 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein gpUL132 PF11359.3 ETO11331.1 - 9.1 5.5 9.8 4.4 6.5 2.3 2.3 2 0 0 2 2 2 0 Glycoprotein UL132 F-box-like PF12937.2 ETO11332.1 - 0.011 15.4 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 F-box-like Atrophin-1 PF03154.10 ETO11332.1 - 5.5 4.9 5.4 8 4.4 3.8 1.1 1 0 0 1 1 1 0 Atrophin-1 family DSPc PF00782.15 ETO11333.1 - 7e-19 67.7 0.8 1.6e-18 66.5 0.1 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 ETO11333.1 - 0.0016 17.8 0.1 0.0016 17.8 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase zf-CCHC_5 PF14787.1 ETO11333.1 - 0.11 12.0 0.3 0.22 11.0 0.2 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger FtsH_ext PF06480.10 ETO11333.1 - 2.6 8.2 6.9 1.5e+02 2.5 4.8 2.7 1 1 0 1 1 1 0 FtsH Extracellular Kelch_6 PF13964.1 ETO11336.1 - 5.6e-09 35.8 1.0 1.2e-05 25.2 0.0 4.3 3 1 1 4 4 4 1 Kelch motif Kelch_3 PF13415.1 ETO11336.1 - 4.4e-07 29.8 0.4 0.0002 21.4 0.0 3.7 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO11336.1 - 4.9e-05 22.7 3.6 0.0053 16.2 0.1 3.8 3 1 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETO11336.1 - 0.00098 18.8 2.1 0.0066 16.2 0.0 3.3 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO11336.1 - 0.0012 18.7 1.5 0.066 13.1 0.2 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO11336.1 - 0.0081 15.9 2.0 0.25 11.1 0.0 3.2 3 0 0 3 3 3 1 Kelch motif WD40 PF00400.27 ETO11337.1 - 5.6e-83 270.1 11.0 1.1e-13 50.5 0.1 7.0 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO11337.1 - 9.8e-11 41.7 0.2 7.5e-05 22.5 0.1 3.2 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO11337.1 - 7.3e-09 34.3 0.5 0.0011 17.3 0.1 2.5 2 1 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.7 ETO11337.1 - 1.4e-08 34.1 7.6 0.25 11.0 0.0 6.1 6 0 0 6 6 6 3 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO11337.1 - 2.2e-06 26.1 5.5 0.048 11.7 0.0 4.3 1 1 3 5 5 5 3 Nucleoporin Nup120/160 DUF1258 PF06869.7 ETO11337.1 - 8.5e-06 25.0 2.0 0.36 9.8 0.1 4.0 2 2 3 5 5 5 3 Protein of unknown function (DUF1258) Gmad1 PF10647.4 ETO11337.1 - 2.3e-05 23.8 0.0 0.22 10.9 0.0 3.4 2 1 1 4 4 4 1 Lipoprotein LpqB beta-propeller domain Nucleoporin_N PF08801.6 ETO11337.1 - 5.6e-05 22.0 7.8 1.2 7.8 0.1 5.2 1 1 4 5 5 5 2 Nup133 N terminal like DUF3312 PF11768.3 ETO11337.1 - 0.0033 15.7 0.3 1.1 7.4 0.0 2.8 2 1 0 3 3 3 2 Protein of unknown function (DUF3312) TFIIIC_delta PF12657.2 ETO11337.1 - 0.0099 15.6 0.4 1.7 8.2 0.0 2.5 2 1 0 2 2 2 1 Transcription factor IIIC subunit delta N-term Mid2 PF04478.7 ETO11337.1 - 0.015 14.7 1.5 0.51 9.7 0.0 3.3 3 2 1 4 4 4 0 Mid2 like cell wall stress sensor GATase PF00117.23 ETO11337.1 - 0.034 13.6 0.0 0.1 12.0 0.0 1.8 2 0 0 2 2 2 0 Glutamine amidotransferase class-I Resistin PF06954.6 ETO11337.1 - 0.045 14.0 0.2 10 6.5 0.0 3.7 4 1 0 5 5 5 0 Resistin Proteasome_A_N PF10584.4 ETO11337.1 - 0.72 9.2 5.2 36 3.8 0.0 4.3 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature RGS-like PF09128.6 ETO11338.1 - 0.027 13.9 0.1 0.033 13.6 0.1 1.2 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain WD40 PF00400.27 ETO11341.1 - 4.5e-87 283.1 20.6 4.2e-14 51.7 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO11341.1 - 7.7e-09 34.2 2.3 0.35 8.9 0.0 5.0 1 1 4 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO11341.1 - 9e-06 24.6 5.8 1.3 7.7 0.3 4.5 1 1 4 5 5 5 3 Nup133 N terminal like PQQ_2 PF13360.1 ETO11341.1 - 7.6e-05 22.2 0.1 0.0033 16.9 0.0 3.0 2 1 0 2 2 2 1 PQQ-like domain Resistin PF06954.6 ETO11341.1 - 0.0006 20.0 2.6 66 3.8 0.0 5.7 1 1 3 6 6 6 0 Resistin Cytochrom_D1 PF02239.11 ETO11341.1 - 0.0011 17.3 0.4 1.6 6.9 0.0 3.1 1 1 3 4 4 4 3 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 ETO11341.1 - 0.0016 17.7 0.1 4.2 6.7 0.0 3.7 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature DPPIV_N PF00930.16 ETO11341.1 - 0.0018 16.9 1.0 0.46 9.0 0.0 4.2 2 1 1 5 5 5 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Ricin_B_lectin PF00652.17 ETO11341.1 - 0.0056 16.6 2.2 0.31 11.0 0.1 3.4 2 2 1 3 3 3 1 Ricin-type beta-trefoil lectin domain PD40 PF07676.7 ETO11341.1 - 0.0065 16.1 8.9 0.8 9.4 0.1 5.8 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat DUF3732 PF12532.3 ETO11341.1 - 0.027 13.9 0.3 0.25 10.8 0.0 2.6 3 1 1 4 4 4 0 Protein of unknown function (DUF3732) DUF3601 PF12208.3 ETO11341.1 - 0.097 12.6 0.0 5.9 6.9 0.0 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF3601) Big_2 PF02368.13 ETO11341.1 - 0.13 12.1 0.6 2.7 7.9 0.1 2.5 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) DUF3618 PF12277.3 ETO11342.1 - 6.7 6.8 14.1 11 6.1 0.2 5.6 7 0 0 7 7 7 0 Protein of unknown function (DUF3618) WD40 PF00400.27 ETO11343.1 - 1.3e-43 145.3 14.5 1.6e-11 43.6 0.1 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO11343.1 - 4.1e-07 28.5 3.1 0.19 9.7 0.0 4.7 2 1 1 5 5 5 4 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO11343.1 - 0.013 15.2 1.7 0.62 9.8 0.1 3.5 2 2 2 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Syntaxin-6_N PF09177.6 ETO11346.1 - 0.017 15.4 10.9 0.017 15.4 7.5 4.6 1 1 3 4 4 4 0 Syntaxin 6, N-terminal IFT57 PF10498.4 ETO11346.1 - 0.068 11.8 78.1 4.3 5.9 17.3 3.4 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 COG2 PF06148.6 ETO11346.1 - 1.5 8.7 49.8 0.027 14.3 8.0 4.8 1 1 4 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.6 ETO11346.1 - 2.5 6.6 86.2 0.016 13.8 17.6 3.6 1 1 3 4 4 4 0 Spc7 kinetochore protein ADIP PF11559.3 ETO11346.1 - 8.1 6.3 90.9 0.021 14.7 16.6 4.0 1 1 4 5 5 5 0 Afadin- and alpha -actinin-Binding RCR PF12273.3 ETO11347.1 - 0.37 11.3 8.9 0.048 14.2 1.1 2.7 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red PLRV_ORF5 PF01690.12 ETO11347.1 - 2.1 7.4 27.8 3.9 6.5 19.3 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Daxx PF03344.10 ETO11347.1 - 7.2 4.9 39.6 14 4.0 27.5 1.4 1 0 0 1 1 1 0 Daxx Family DUF4167 PF13763.1 ETO11348.1 - 0.66 10.0 13.3 0.12 12.3 5.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4167) Imm21 PF15569.1 ETO11349.1 - 0.041 13.6 0.2 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 Immunity protein 21 DUF4071 PF13281.1 ETO11350.1 - 0.0026 16.6 0.1 0.0027 16.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4071) DUF3959 PF13105.1 ETO11350.1 - 1.5 8.1 5.3 2.4 7.4 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) FtsX PF02687.16 ETO11352.1 - 1.3e-16 60.3 16.9 1.3e-16 60.3 11.7 1.9 2 0 0 2 2 2 1 FtsX-like permease family DUF947 PF06102.7 ETO11354.1 - 0.25 11.1 8.9 0.03 14.1 2.7 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF947) Histone PF00125.19 ETO11355.1 - 8.7e-20 70.6 0.1 1.5e-19 69.9 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 ETO11355.1 - 8.3e-07 28.9 0.6 1.4e-06 28.2 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RP-C PF03428.8 ETO11355.1 - 0.022 14.2 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Replication protein C N-terminal domain TFIID_20kDa PF03847.8 ETO11355.1 - 0.12 12.6 0.5 0.46 10.7 0.1 1.9 1 1 1 2 2 2 0 Transcription initiation factor TFIID subunit A Actin PF00022.14 ETO11356.1 - 2.3e-90 302.8 0.0 2.8e-90 302.6 0.0 1.0 1 0 0 1 1 1 1 Actin DUF4271 PF14093.1 ETO11358.1 - 0.043 13.4 2.0 0.072 12.7 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) Apc5 PF12862.2 ETO11358.1 - 0.089 12.6 0.9 0.2 11.5 0.1 1.9 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 Ras PF00071.17 ETO11359.1 - 2.4e-33 114.8 1.0 9.2e-24 83.6 0.0 2.8 2 1 0 2 2 2 2 Ras family Miro PF08477.8 ETO11359.1 - 3.6e-13 50.0 0.0 6.3e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein PsaD PF02531.11 ETO11359.1 - 0.027 13.6 0.2 7 5.8 0.0 2.3 2 0 0 2 2 2 0 PsaD Peptidase_C1 PF00112.18 ETO11360.1 - 4.9e-55 186.7 5.3 4.9e-55 186.7 3.7 2.0 3 0 0 3 3 3 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 ETO11360.1 - 4.5e-15 55.6 0.3 9.1e-15 54.6 0.2 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 ETO11360.1 - 0.0003 19.4 0.8 0.00053 18.6 0.2 1.5 2 0 0 2 2 2 1 Peptidase C1-like family Steroid_dh PF02544.11 ETO11361.1 - 2.1e-37 128.1 2.4 2.1e-37 128.1 1.7 1.5 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase Adeno_E3B PF03376.9 ETO11361.1 - 0.0056 16.5 0.8 0.017 15.0 0.1 2.2 2 0 0 2 2 2 1 Adenovirus E3B protein Methyltransf_18 PF12847.2 ETO11362.1 - 2.6e-05 24.7 0.0 7.3e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain zf-TRAF PF02176.13 ETO11362.1 - 0.00012 22.3 3.0 0.00021 21.5 1.1 2.2 2 0 0 2 2 2 1 TRAF-type zinc finger Methyltransf_31 PF13847.1 ETO11362.1 - 0.01 15.4 0.4 0.036 13.6 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain PCMT PF01135.14 ETO11362.1 - 0.028 13.9 0.0 0.34 10.4 0.0 2.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF4376 PF14301.1 ETO11363.1 - 0.0021 18.1 1.1 0.0047 17.0 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4376) DUF1492 PF07374.6 ETO11365.1 - 0.033 14.2 0.2 0.12 12.4 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1492) DUF1143 PF06608.6 ETO11366.1 - 0.12 12.4 0.1 6.2 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1143) Glyco_hydro_35 PF01301.14 ETO11367.1 - 0.11 11.8 0.4 0.16 11.2 0.0 1.4 2 0 0 2 2 2 0 Glycosyl hydrolases family 35 Epimerase PF01370.16 ETO11368.1 - 1.6e-19 70.2 0.0 3.6e-19 69.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETO11368.1 - 1.7e-15 57.4 0.0 4.7e-13 49.5 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 ETO11368.1 - 1.5e-14 53.4 0.0 2.3e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 ETO11368.1 - 5.8e-08 31.9 0.0 1.2e-07 30.8 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 ETO11368.1 - 3.1e-07 29.8 0.0 0.00029 20.1 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family adh_short PF00106.20 ETO11368.1 - 1.9e-05 24.6 0.0 3.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETO11368.1 - 0.0043 16.7 0.0 0.012 15.3 0.0 1.7 2 0 0 2 2 2 1 KR domain zf-DHHC PF01529.15 ETO11369.1 - 8.5e-24 83.8 33.2 2.6e-17 62.7 13.7 3.8 3 2 0 3 3 3 2 DHHC palmitoyltransferase DZR PF12773.2 ETO11369.1 - 0.054 13.3 0.5 0.054 13.3 0.3 2.5 2 1 0 2 2 2 0 Double zinc ribbon zf-TAZ PF02135.11 ETO11369.1 - 1.1 9.2 8.2 0.32 11.0 2.0 2.5 2 0 0 2 2 2 0 TAZ zinc finger FYVE PF01363.16 ETO11369.1 - 4.5 7.2 13.4 0.62 10.0 5.3 2.4 2 1 0 2 2 2 0 FYVE zinc finger WD40 PF00400.27 ETO11371.1 - 5.3e-18 64.1 1.2 1.2e-08 34.5 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO11371.1 - 0.098 11.3 0.7 0.23 10.1 0.5 1.6 1 1 0 1 1 1 0 Nup133 N terminal like Nup160 PF11715.3 ETO11371.1 - 0.11 10.5 0.0 0.24 9.4 0.0 1.5 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Beta_helix PF13229.1 ETO11371.1 - 0.13 12.0 5.8 0.24 11.1 3.9 1.5 1 1 0 1 1 1 0 Right handed beta helix region Kelch_5 PF13854.1 ETO11372.1 - 0.11 12.4 0.7 2.4 8.2 0.0 3.0 3 0 0 3 3 3 0 Kelch motif Notch PF00066.12 ETO11374.1 - 1.9e-19 69.5 33.3 1.1e-10 41.5 11.5 2.3 2 0 0 2 2 2 2 LNR domain DUF3184 PF11380.3 ETO11374.1 - 0.0042 15.0 0.1 0.0042 15.0 0.1 3.2 3 1 1 4 4 4 2 Protein of unknown function (DUF3184) RRM_1 PF00076.17 ETO11376.1 - 8.2e-12 44.5 0.1 2.2e-11 43.1 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO11376.1 - 5.8e-11 42.2 0.0 1.1e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO11376.1 - 2e-06 27.5 0.7 4.5e-06 26.4 0.5 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mem_trans PF03547.13 ETO11376.1 - 0.023 13.0 1.0 0.024 12.9 0.7 1.1 1 0 0 1 1 1 0 Membrane transport protein Ndc1_Nup PF09531.5 ETO11376.1 - 0.28 9.5 8.8 0.34 9.2 6.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.12 ETO11376.1 - 1.4 7.6 8.5 2 7.1 5.9 1.2 1 0 0 1 1 1 0 Presenilin DDHD PF02862.12 ETO11376.1 - 1.7 8.3 12.8 2.7 7.7 8.9 1.3 1 0 0 1 1 1 0 DDHD domain TMEM247 PF15444.1 ETO11376.1 - 4.2 7.1 6.8 6.1 6.6 4.7 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 Ebp2 PF05890.7 ETO11377.1 - 2.2e-39 135.4 28.4 3.8e-39 134.6 19.5 1.5 1 1 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 EF-hand_1 PF00036.27 ETO11379.1 - 1.8e-12 45.5 7.0 6.9e-05 21.8 0.4 3.6 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 ETO11379.1 - 5.9e-12 45.5 5.2 5.2e-06 26.5 2.4 2.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 ETO11379.1 - 1.5e-10 39.9 1.7 0.00018 21.1 0.1 4.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 ETO11379.1 - 5.2e-05 22.7 6.9 0.12 12.0 0.0 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 ETO11379.1 - 0.0002 21.0 4.1 0.0026 17.4 0.0 2.9 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 ETO11379.1 - 0.051 13.6 0.6 0.86 9.6 0.1 2.3 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.1 ETO11379.1 - 0.4 10.1 9.5 0.73 9.2 0.9 3.3 3 0 0 3 3 3 0 EF hand Ldh_1_C PF02866.13 ETO11380.1 - 7e-35 120.3 0.0 6.8e-34 117.1 0.0 1.9 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 ETO11380.1 - 4.8e-12 45.9 0.1 8.2e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Glyco_hydro_63 PF03200.11 ETO11381.1 - 0.017 13.0 2.5 0.019 12.8 1.8 1.0 1 0 0 1 1 1 0 Mannosyl oligosaccharide glucosidase Xol-1_GHMP-like PF09109.5 ETO11381.1 - 0.027 14.5 0.1 0.054 13.5 0.1 1.4 1 0 0 1 1 1 0 Switch protein XOL-1, GHMP-like zf-RanBP PF00641.13 ETO11382.1 - 1.3e-05 24.2 1.3 2.9e-05 23.0 0.9 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.10 ETO11382.1 - 0.018 14.5 0.1 0.018 14.5 0.0 2.3 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Kelch_6 PF13964.1 ETO11383.1 - 7.4e-09 35.4 2.7 0.0091 16.1 0.1 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO11383.1 - 3.3e-05 23.3 0.7 0.13 11.7 0.1 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO11383.1 - 8.1e-05 22.2 1.6 0.22 11.3 0.0 4.4 5 1 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO11383.1 - 0.00067 19.3 0.0 6 6.7 0.0 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO11383.1 - 0.0028 17.5 0.3 28 4.8 0.0 4.1 4 0 0 4 4 4 1 Kelch motif AAA PF00004.24 ETO11384.1 - 1.7e-06 28.2 0.0 3.3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 ETO11384.1 - 0.00032 20.1 0.0 0.0073 15.7 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein RuvB_N PF05496.7 ETO11384.1 - 0.00049 19.2 0.0 0.00083 18.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 ETO11384.1 - 0.00058 20.6 0.0 0.0025 18.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 ETO11384.1 - 0.0025 18.1 0.0 0.0061 16.8 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 ETO11384.1 - 0.0026 17.8 0.3 0.089 12.9 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 ETO11384.1 - 0.003 17.8 0.0 0.0073 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETO11384.1 - 0.003 17.5 0.0 0.0063 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 ETO11384.1 - 0.0054 16.6 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 ETO11384.1 - 0.0056 16.1 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.9 ETO11384.1 - 0.009 15.7 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 ETO11384.1 - 0.009 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 ETO11384.1 - 0.012 15.7 0.0 0.036 14.2 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.21 ETO11384.1 - 0.047 13.1 0.0 0.1 12.0 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF258 PF03193.11 ETO11384.1 - 0.049 12.8 0.0 0.081 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_19 PF13245.1 ETO11384.1 - 0.057 13.1 0.1 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activ_2 PF14532.1 ETO11384.1 - 0.061 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain MobB PF03205.9 ETO11384.1 - 0.078 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 ETO11384.1 - 0.079 12.6 0.0 0.21 11.2 0.0 1.8 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.10 ETO11384.1 - 0.099 12.3 0.0 0.28 10.8 0.0 1.8 1 0 0 1 1 1 0 NTPase AAA_23 PF13476.1 ETO11384.1 - 0.26 11.5 3.5 0.28 11.4 0.8 2.3 2 1 0 2 2 1 0 AAA domain Peptidase_S7 PF00949.16 ETO11385.1 - 0.079 12.3 0.1 0.21 10.9 0.1 1.7 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease AAA_22 PF13401.1 ETO11387.1 - 0.011 15.8 0.1 0.14 12.2 0.0 2.9 2 2 0 2 2 2 0 AAA domain AAA PF00004.24 ETO11387.1 - 0.042 14.0 0.3 0.19 11.9 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETO11387.1 - 0.068 12.8 0.0 0.4 10.3 0.0 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 ETO11387.1 - 0.13 12.2 0.0 0.94 9.4 0.0 2.3 1 1 1 2 2 2 0 AAA ATPase domain Spore_III_AB PF09548.5 ETO11387.1 - 1.1 8.9 7.1 3.6 7.3 0.2 3.4 4 0 0 4 4 4 0 Stage III sporulation protein AB (spore_III_AB) EST1_DNA_bind PF10373.4 ETO11388.1 - 0.031 13.5 0.6 0.05 12.8 0.4 1.3 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain TM1586_NiRdase PF14512.1 ETO11389.1 - 0.09 11.9 0.6 0.25 10.4 0.2 1.8 2 0 0 2 2 2 0 Putative TM nitroreductase ThiF PF00899.16 ETO11389.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 ThiF family Kelch_1 PF01344.20 ETO11390.1 - 0.00042 19.7 0.1 0.0033 16.9 0.0 2.5 3 0 0 3 3 3 1 Kelch motif CodY PF06018.9 ETO11390.1 - 0.014 14.7 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 CodY GAF-like domain Kelch_6 PF13964.1 ETO11390.1 - 0.071 13.3 2.4 16 5.9 0.0 3.8 4 0 0 4 4 4 0 Kelch motif HMG_box_2 PF09011.5 ETO11390.1 - 1 9.7 4.3 0.44 10.9 0.1 2.1 2 0 0 2 2 2 0 HMG-box domain WD40 PF00400.27 ETO11391.1 - 4.6e-60 197.4 15.7 4.2e-13 48.6 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO11391.1 - 3.2e-09 36.7 2.1 6e-05 22.8 0.1 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO11391.1 - 9.9e-07 27.2 6.0 0.033 12.3 0.1 4.0 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO11391.1 - 0.00019 19.8 1.0 0.34 9.1 0.0 2.9 1 1 2 3 3 3 2 Cytochrome D1 heme domain DPPIV_N PF00930.16 ETO11391.1 - 0.0018 16.9 0.1 0.023 13.2 0.0 2.3 1 1 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF1258 PF06869.7 ETO11391.1 - 0.0032 16.5 1.0 0.028 13.5 0.3 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF1258) PD40 PF07676.7 ETO11391.1 - 0.0049 16.5 1.4 2.8 7.7 0.0 3.8 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat BBS2_Mid PF14783.1 ETO11391.1 - 0.0078 15.9 2.0 0.18 11.6 0.1 3.6 2 2 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region LBP_BPI_CETP_C PF02886.12 ETO11391.1 - 0.018 14.2 0.0 4.7 6.3 0.0 2.4 2 0 0 2 2 2 0 LBP / BPI / CETP family, C-terminal domain GATase PF00117.23 ETO11391.1 - 0.027 13.9 0.0 0.6 9.5 0.0 2.4 1 1 0 1 1 1 0 Glutamine amidotransferase class-I Resistin PF06954.6 ETO11391.1 - 0.027 14.7 4.9 25 5.2 0.1 4.3 1 1 4 5 5 5 0 Resistin DUF3312 PF11768.3 ETO11391.1 - 0.031 12.5 0.1 0.19 9.8 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3312) Mid2 PF04478.7 ETO11391.1 - 0.075 12.4 1.9 37 3.7 0.0 3.5 2 2 1 3 3 3 0 Mid2 like cell wall stress sensor Methyltransf_3 PF01596.12 ETO11391.1 - 0.085 11.8 0.0 6.4 5.7 0.0 2.8 1 1 2 3 3 3 0 O-methyltransferase Proteasome_A_N PF10584.4 ETO11391.1 - 1.8 7.9 5.6 7.2 6.0 0.0 3.6 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Ras PF00071.17 ETO11392.1 - 8.2e-19 67.5 0.0 1.1e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Arf PF00025.16 ETO11392.1 - 9.1e-05 21.7 0.1 0.00015 21.0 0.1 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 ETO11392.1 - 0.00021 21.7 0.0 0.00064 20.2 0.0 1.9 2 1 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 ETO11392.1 - 0.00091 18.4 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 ETO11392.1 - 0.013 14.9 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Prion PF00377.13 ETO11393.1 - 0.0085 15.7 2.7 0.01 15.5 0.9 2.0 1 1 1 2 2 2 1 Prion/Doppel alpha-helical domain Peptidase_C74 PF12387.3 ETO11393.1 - 0.075 12.1 1.3 0.091 11.9 0.8 1.3 1 1 0 1 1 1 0 Pestivirus NS2 peptidase TRM13 PF05206.9 ETO11393.1 - 0.18 11.0 5.8 0.24 10.5 4.0 1.2 1 0 0 1 1 1 0 Methyltransferase TRM13 GLTSCR1 PF15249.1 ETO11393.1 - 0.41 10.7 4.7 0.54 10.3 0.2 2.1 1 1 1 2 2 2 0 Glioma tumor suppressor candidate region MoCo_carrier PF12694.2 ETO11394.1 - 8.3e-40 135.5 0.1 2.4e-39 134.0 0.0 1.8 1 0 0 1 1 1 1 Putative molybdenum carrier SNF2_N PF00176.18 ETO11395.1 - 1.3e-49 168.6 2.4 1.7e-49 168.2 1.7 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 ETO11395.1 - 7.6e-10 38.9 0.0 1.6e-09 37.8 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 ETO11395.1 - 2.3e-06 27.2 0.0 4.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 ETO11395.1 - 0.094 12.8 0.2 0.26 11.4 0.2 1.9 1 1 0 1 1 1 0 AAA domain ATP-synt_8 PF00895.15 ETO11396.1 - 0.51 10.5 2.5 0.52 10.5 0.3 2.0 2 0 0 2 2 2 0 ATP synthase protein 8 Phospholamban PF04272.9 ETO11396.1 - 3.7 7.0 6.2 3 7.3 3.4 1.5 1 1 0 1 1 1 0 Phospholamban PBP_sp32 PF07222.7 ETO11397.1 - 4.6 6.3 6.2 4 6.5 3.6 1.3 1 1 0 1 1 1 0 Proacrosin binding protein sp32 ORC2 PF04084.9 ETO11399.1 - 8.3e-42 143.1 0.1 9.5e-42 142.9 0.1 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 2 DUF1649 PF07855.7 ETO11401.1 - 1e-10 41.5 0.5 1.2e-10 41.2 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) Kelch_2 PF07646.10 ETO11402.1 - 1.1e-06 28.1 0.7 0.00034 20.2 0.1 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 ETO11402.1 - 8.7e-06 25.4 0.5 0.074 12.8 0.1 2.4 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO11402.1 - 0.0004 20.4 3.0 0.059 13.5 0.3 2.6 1 1 1 2 2 2 2 Kelch motif Kelch_5 PF13854.1 ETO11402.1 - 0.0034 17.3 3.9 0.16 11.9 0.3 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.20 ETO11402.1 - 0.0041 16.6 4.6 0.017 14.6 0.9 2.2 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO11402.1 - 0.068 13.3 0.3 0.35 11.0 0.0 2.0 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO11404.1 - 2.2e-06 27.5 1.5 0.0076 16.3 0.1 4.3 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 ETO11404.1 - 3.6e-06 26.4 5.6 0.00027 20.4 0.1 4.0 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 ETO11404.1 - 4.8e-05 22.9 3.3 0.016 14.9 0.1 4.5 4 1 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO11404.1 - 0.00049 19.8 0.2 0.15 11.8 0.0 3.4 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO11404.1 - 0.028 14.5 0.1 2.5 8.3 0.0 3.3 4 0 0 4 4 4 0 Galactose oxidase, central domain tRNA-synt_1c_C PF03950.13 ETO11404.1 - 0.054 13.1 0.1 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain Kelch_5 PF13854.1 ETO11404.1 - 0.9 9.5 6.2 1 9.4 0.5 3.6 4 0 0 4 4 4 0 Kelch motif LMF1 PF06762.9 ETO11405.1 - 2.2e-62 211.0 21.2 9.2e-62 209.0 14.7 1.8 1 1 0 1 1 1 1 Lipase maturation factor Kelch_5 PF13854.1 ETO11406.1 - 2.3e-05 24.2 4.5 0.1 12.5 0.1 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO11406.1 - 0.071 12.6 4.2 6.6 6.3 0.2 3.7 4 0 0 4 4 4 0 Kelch motif Kelch_3 PF13415.1 ETO11406.1 - 0.35 11.1 7.4 40 4.5 0.6 4.5 4 1 0 4 4 4 0 Galactose oxidase, central domain WD40 PF00400.27 ETO11407.1 - 8.3e-83 269.6 19.5 8.7e-13 47.6 0.2 7.0 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO11407.1 - 7.3e-16 58.4 0.1 0.00032 20.4 0.0 3.6 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO11407.1 - 1.7e-10 39.6 8.0 0.034 12.2 0.1 4.9 1 1 4 5 5 5 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO11407.1 - 2.9e-07 29.1 3.6 0.014 13.6 0.1 3.2 1 1 1 3 3 3 3 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO11407.1 - 3.3e-07 29.4 12.1 0.61 8.7 0.5 5.9 1 1 3 4 4 4 3 Nup133 N terminal like PQQ_2 PF13360.1 ETO11407.1 - 4.6e-06 26.2 0.9 0.00056 19.4 0.5 3.3 1 1 1 2 2 2 2 PQQ-like domain Ricin_B_lectin PF00652.17 ETO11407.1 - 0.00031 20.7 4.3 0.12 12.4 0.2 3.3 1 1 2 3 3 3 1 Ricin-type beta-trefoil lectin domain PD40 PF07676.7 ETO11407.1 - 0.00057 19.4 3.1 4.6 7.0 0.0 5.1 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 ETO11407.1 - 0.001 18.2 1.1 5.1 6.1 0.0 4.1 1 1 4 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Resistin PF06954.6 ETO11407.1 - 0.0017 18.6 0.1 93 3.3 0.0 4.9 1 1 3 5 5 5 0 Resistin DUF1652 PF07865.6 ETO11407.1 - 0.0018 17.8 0.0 0.71 9.5 0.0 3.8 4 0 0 4 4 4 1 Protein of unknown function (DUF1652) DPPIV_N PF00930.16 ETO11407.1 - 0.0032 16.1 0.1 5.6 5.4 0.0 3.3 1 1 0 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF1513 PF07433.6 ETO11407.1 - 0.06 12.2 0.5 11 4.8 0.0 3.4 2 2 1 4 4 4 0 Protein of unknown function (DUF1513) CPSF_A PF03178.10 ETO11407.1 - 0.086 11.9 0.2 1.8 7.5 0.0 2.7 2 1 1 3 3 3 0 CPSF A subunit region Proteasome_A_N PF10584.4 ETO11407.1 - 0.088 12.1 5.5 24 4.3 0.0 4.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature TFIIA PF03153.8 ETO11408.1 - 7.9 6.2 21.9 12 5.6 15.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.27 ETO11409.1 - 4.2e-24 83.4 1.1 1.8e-09 37.1 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO11409.1 - 0.004 15.3 0.2 1.2 7.1 0.0 2.8 2 1 2 4 4 4 2 Nucleoporin Nup120/160 YMF19 PF02326.10 ETO11410.1 - 1.9 9.0 8.7 2.9 8.5 0.5 2.6 2 0 0 2 2 2 0 Plant ATP synthase F0 BRCT PF00533.21 ETO11411.1 - 0.11 12.6 0.7 0.39 10.9 0.1 2.1 1 1 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain ubiquitin PF00240.18 ETO11412.1 - 1.5e-17 62.7 1.2 2.4e-17 62.0 0.9 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 ETO11412.1 - 5.7e-10 38.7 1.4 8.7e-10 38.1 1.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UN_NPL4 PF11543.3 ETO11412.1 - 0.00086 19.5 1.5 0.0016 18.6 1.0 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 Ubiquitin_2 PF14560.1 ETO11412.1 - 0.0046 17.1 0.5 0.016 15.4 0.4 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain DUF3715 PF12509.3 ETO11412.1 - 0.02 14.7 0.7 0.044 13.6 0.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3715) Mut7-C PF01927.11 ETO11412.1 - 0.11 12.4 0.2 0.18 11.7 0.1 1.5 1 1 0 1 1 1 0 Mut7-C RNAse domain Ceramidase PF05875.7 ETO11413.1 - 0.00012 21.2 0.3 0.00013 21.2 0.2 1.2 1 0 0 1 1 1 1 Ceramidase MCM PF00493.18 ETO11414.1 - 1.4e-114 382.3 0.2 9.1e-103 343.5 0.1 2.2 2 0 0 2 2 2 2 MCM2/3/5 family Mg_chelatase PF01078.16 ETO11414.1 - 5.5e-05 22.4 1.3 0.0002 20.6 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Mg_chelatase_2 PF13335.1 ETO11414.1 - 0.014 15.7 0.8 0.24 11.8 0.1 3.2 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI MCM_N PF14551.1 ETO11414.1 - 0.015 15.7 0.2 0.34 11.4 0.0 2.8 2 1 1 3 3 3 0 MCM N-terminal domain RecX PF02631.11 ETO11414.1 - 0.039 14.1 0.1 0.093 12.9 0.1 1.6 1 0 0 1 1 1 0 RecX family Annexin PF00191.15 ETO11415.1 - 1.7e-05 24.6 1.1 4.7e-05 23.2 0.1 2.2 2 0 0 2 2 2 1 Annexin DUF4200 PF13863.1 ETO11415.1 - 0.00014 21.8 11.0 0.00014 21.8 7.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) MRP-S26 PF14943.1 ETO11415.1 - 0.00063 19.3 3.9 0.0011 18.5 2.7 1.4 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S26 EzrA PF06160.7 ETO11415.1 - 0.013 13.7 8.4 0.016 13.4 5.8 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA HAUS-augmin3 PF14932.1 ETO11415.1 - 0.051 12.7 10.9 0.095 11.8 7.5 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Syntaxin PF00804.20 ETO11415.1 - 0.097 12.8 7.6 0.22 11.7 5.3 1.5 1 0 0 1 1 1 0 Syntaxin ERM PF00769.14 ETO11415.1 - 0.19 11.2 11.5 0.33 10.4 8.0 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family UPF0242 PF06785.6 ETO11415.1 - 0.29 9.7 7.1 0.48 9.0 4.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) APG6 PF04111.7 ETO11415.1 - 0.3 10.0 12.5 0.49 9.4 8.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 ETO11415.1 - 0.71 8.2 6.5 1.1 7.5 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF641 PF04859.7 ETO11415.1 - 0.99 9.1 9.6 0.27 10.9 3.5 2.3 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) IncA PF04156.9 ETO11415.1 - 1 8.8 15.1 1 8.9 8.2 2.0 2 0 0 2 2 2 0 IncA protein Seryl_tRNA_N PF02403.17 ETO11415.1 - 1.6 8.7 11.7 6.5 6.8 6.4 2.6 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF2968 PF11180.3 ETO11415.1 - 1.9 7.8 9.1 3.2 7.1 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) OmpH PF03938.9 ETO11415.1 - 2.3 8.1 14.7 1.6 8.6 8.9 1.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) bZIP_1 PF00170.16 ETO11415.1 - 6 6.9 14.7 7.8 6.5 1.7 3.9 2 1 2 4 4 4 0 bZIP transcription factor BT1 PF03092.11 ETO11416.1 - 7.4e-13 47.9 23.5 1.4e-12 47.0 11.8 2.6 2 1 0 2 2 2 2 BT1 family Rad51 PF08423.6 ETO11417.1 - 3.4e-111 370.2 0.2 7e-111 369.2 0.0 1.5 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.1 ETO11417.1 - 2.1e-12 46.8 0.0 3.1e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 ETO11417.1 - 4.4e-11 42.3 0.3 1.9e-10 40.2 0.0 2.1 3 0 0 3 3 3 1 KaiC RecA PF00154.16 ETO11417.1 - 1.3e-09 37.5 0.1 1.8e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 ETO11417.1 - 1.2e-07 31.8 0.1 2.5e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_22 PF13401.1 ETO11417.1 - 0.0029 17.7 0.0 0.0059 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 ETO11417.1 - 0.033 14.3 0.0 0.084 13.0 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4403 PF14356.1 ETO11418.1 - 0.079 11.2 0.0 0.088 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4403) Peptidase_C14 PF00656.17 ETO11420.1 - 6.2e-11 42.4 0.3 6.2e-11 42.4 0.2 2.0 2 0 0 2 2 2 1 Caspase domain Kelch_6 PF13964.1 ETO11420.1 - 6.2e-05 22.9 0.5 0.014 15.5 0.1 3.7 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.20 ETO11420.1 - 8.7e-05 21.9 2.2 0.00047 19.6 0.1 3.2 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETO11420.1 - 0.0005 19.7 0.0 0.21 11.3 0.0 3.4 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO11420.1 - 0.0053 16.6 3.4 0.3 11.0 0.3 3.9 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.10 ETO11420.1 - 0.025 14.3 1.3 0.47 10.3 0.1 3.6 4 0 0 4 4 4 0 Kelch motif Kelch_3 PF13415.1 ETO11420.1 - 0.12 12.6 0.1 0.89 9.8 0.0 2.6 3 0 0 3 3 3 0 Galactose oxidase, central domain DUF506 PF04720.7 ETO11421.1 - 2.7 7.5 5.0 5.4 6.5 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF506) WD40 PF00400.27 ETO11422.1 - 3.2e-69 226.5 7.8 3.7e-13 48.7 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO11422.1 - 1.1e-08 34.9 0.1 0.0017 18.1 0.0 2.8 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO11422.1 - 7.1e-08 31.9 6.3 0.032 13.8 0.1 5.5 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO11422.1 - 2.3e-05 22.7 3.1 0.76 7.8 0.1 3.7 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nbas_N PF15492.1 ETO11422.1 - 4.1e-05 22.8 0.8 0.91 8.5 0.0 4.0 1 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 ETO11422.1 - 0.0002 20.2 3.2 0.017 13.8 0.2 2.9 2 2 0 3 3 3 2 Nup133 N terminal like DPPIV_N PF00930.16 ETO11422.1 - 0.00063 18.4 0.0 3.1 6.3 0.0 3.3 1 1 3 4 4 4 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region PQQ_2 PF13360.1 ETO11422.1 - 0.0019 17.6 0.2 0.15 11.4 0.1 3.3 1 1 0 1 1 1 1 PQQ-like domain Proteasome_A_N PF10584.4 ETO11422.1 - 0.002 17.4 3.1 4.3 6.7 0.0 4.9 5 0 0 5 5 5 1 Proteasome subunit A N-terminal signature Cytochrom_D1 PF02239.11 ETO11422.1 - 0.0031 15.8 0.1 0.1 10.8 0.0 2.5 1 1 1 3 3 3 2 Cytochrome D1 heme domain DUF1797 PF08796.5 ETO11422.1 - 0.02 14.7 0.0 43 4.0 0.0 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1797) NodS PF05401.6 ETO11422.1 - 0.064 12.6 0.6 1.7 7.9 0.1 2.5 2 2 0 2 2 2 0 Nodulation protein S (NodS) BBS2_Mid PF14783.1 ETO11422.1 - 0.07 12.9 2.9 11 5.8 0.1 3.6 2 2 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region IKI3 PF04762.7 ETO11422.1 - 0.08 10.7 0.1 1.9 6.1 0.0 2.4 2 1 1 3 3 3 0 IKI3 family Resistin PF06954.6 ETO11422.1 - 0.32 11.3 3.1 22 5.4 0.0 3.2 2 2 0 3 3 3 0 Resistin MyTH4 PF00784.12 ETO11423.1 - 0.015 15.1 1.6 0.065 13.1 0.0 2.4 1 1 1 2 2 2 0 MyTH4 domain DUF912 PF06024.7 ETO11426.1 - 0.028 14.4 2.9 0.12 12.4 2.0 2.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Claudin_2 PF13903.1 ETO11426.1 - 0.11 12.2 0.9 0.2 11.3 0.6 1.4 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction PUB PF09409.5 ETO11427.1 - 3e-07 30.1 0.0 6.8e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 PUB domain zf-RanBP PF00641.13 ETO11427.1 - 0.0062 15.6 0.4 0.0062 15.6 0.3 1.6 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.10 ETO11427.1 - 0.011 15.2 0.8 0.024 14.1 0.2 1.7 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger RasGEF PF00617.14 ETO11428.1 - 1.5e-18 67.2 3.5 5.3e-11 42.5 0.2 2.9 2 2 1 3 3 3 2 RasGEF domain RasGEF_N PF00618.15 ETO11428.1 - 7.7e-08 32.3 1.0 2.1e-07 30.9 0.7 1.8 1 1 0 1 1 1 1 RasGEF N-terminal motif Vasculin PF15337.1 ETO11428.1 - 0.0056 17.1 1.3 0.0056 17.1 0.9 2.0 2 0 0 2 2 2 1 Vascular protein family Vasculin-like 1 COMPASS-Shg1 PF05205.7 ETO11428.1 - 0.03 14.6 0.6 0.06 13.6 0.4 1.6 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 Gag_p17 PF00540.13 ETO11429.1 - 0.015 15.0 0.2 0.023 14.4 0.1 1.4 1 0 0 1 1 1 0 gag gene protein p17 (matrix protein) PspB PF06667.7 ETO11430.1 - 0.065 13.1 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Phage shock protein B Med13_C PF06333.7 ETO11430.1 - 0.12 10.8 1.5 0.1 11.1 0.2 1.5 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal Gp49 PF05973.9 ETO11430.1 - 0.51 10.3 0.1 0.51 10.3 0.0 2.7 3 1 0 3 3 3 0 Phage derived protein Gp49-like (DUF891) Peptidase_U57 PF05582.7 ETO11433.1 - 0.062 12.2 0.6 0.077 11.9 0.4 1.0 1 0 0 1 1 1 0 YabG peptidase U57 Peroxin-13_N PF04088.8 ETO11433.1 - 0.76 9.7 3.2 1 9.3 2.2 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region CAP_GLY PF01302.20 ETO11435.1 - 1.6e-12 46.9 0.3 2.8e-12 46.1 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain Sina PF03145.11 ETO11437.1 - 6.2e-06 26.0 0.3 6.2e-06 26.0 0.2 2.4 1 1 1 2 2 2 1 Seven in absentia protein family Ogr_Delta PF04606.7 ETO11437.1 - 0.0014 18.2 1.6 0.0045 16.6 0.0 2.6 2 0 0 2 2 2 1 Ogr/Delta-like zinc finger RasGEF PF00617.14 ETO11438.1 - 2.4e-25 89.3 3.5 4.9e-25 88.3 0.6 2.4 2 1 0 2 2 2 1 RasGEF domain DUF4642 PF15484.1 ETO11439.1 - 0.07 13.0 3.1 0.1 12.5 2.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4642) FGF-BP1 PF06473.7 ETO11440.1 - 0.044 13.3 1.2 0.065 12.8 0.8 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) WD40 PF00400.27 ETO11441.1 - 1.4e-85 278.3 20.7 7.8e-14 50.9 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO11441.1 - 7.6e-15 54.0 0.1 8.4e-08 30.8 0.0 3.1 2 1 1 3 3 3 3 Cytochrome D1 heme domain eIF2A PF08662.6 ETO11441.1 - 4.3e-11 42.9 0.0 0.00027 20.7 0.0 3.5 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO11441.1 - 8.9e-09 34.0 7.2 0.4 8.7 0.0 5.3 1 1 4 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO11441.1 - 4.9e-06 25.5 8.4 0.61 8.7 0.2 5.5 1 1 3 4 4 4 4 Nup133 N terminal like PD40 PF07676.7 ETO11441.1 - 1.5e-05 24.5 12.7 4.9 6.9 0.0 7.0 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO11441.1 - 0.00013 22.1 0.8 23 5.3 0.0 4.5 2 2 3 5 5 5 0 Resistin Nbas_N PF15492.1 ETO11441.1 - 0.00045 19.4 2.7 11 5.0 0.1 4.4 2 1 3 5 5 5 2 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 ETO11441.1 - 0.00074 19.0 0.4 0.1 12.0 0.2 2.9 2 1 0 2 2 2 1 PQQ-like domain Rav1p_C PF12234.3 ETO11441.1 - 0.21 9.7 0.9 5.1 5.1 0.0 2.2 2 1 1 3 3 3 0 RAVE protein 1 C terminal Proteasome_A_N PF10584.4 ETO11441.1 - 2.2 7.6 11.8 9.9 5.5 0.0 5.2 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature DUF1075 PF06388.6 ETO11443.1 - 0.067 12.8 0.1 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1075) DUF4576 PF15144.1 ETO11443.1 - 0.15 11.6 0.9 1.6 8.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4576) RhoGAP PF00620.22 ETO11444.1 - 0.0045 16.6 0.0 0.01 15.4 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain COG6 PF06419.6 ETO11445.1 - 0.1 10.7 0.1 0.12 10.4 0.1 1.0 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 CLASP_N PF12348.3 ETO11446.1 - 0.0002 20.7 0.0 0.22 10.8 0.0 2.5 3 0 0 3 3 3 2 CLASP N terminal Cnd1 PF12717.2 ETO11446.1 - 0.0015 18.4 0.0 2.6 7.8 0.0 2.5 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Kelch_1 PF01344.20 ETO11447.1 - 9e-06 25.1 5.6 0.02 14.4 0.2 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO11447.1 - 1.1e-05 24.9 3.0 0.011 15.5 0.1 4.4 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 ETO11447.1 - 0.00013 21.7 0.0 1.6 8.7 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO11447.1 - 0.0012 18.9 5.4 4.8 7.5 0.2 5.2 4 2 2 6 6 6 2 Kelch motif MACPF PF01823.14 ETO11447.1 - 0.13 11.9 2.9 2.5 7.7 0.2 2.9 3 0 0 3 3 3 0 MAC/Perforin domain WD40 PF00400.27 ETO11448.1 - 7.5e-11 41.4 0.5 1.4e-10 40.6 0.4 1.4 1 0 0 1 1 1 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO11448.1 - 0.039 12.1 0.1 0.039 12.1 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DUF3915 PF13054.1 ETO11448.1 - 0.042 13.7 0.1 0.051 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) AA_permease PF00324.16 ETO11450.1 - 7.1e-26 90.5 20.5 1e-25 90.0 14.2 1.2 1 0 0 1 1 1 1 Amino acid permease Kinesin-relat_1 PF12711.2 ETO11451.1 - 0.0038 17.6 4.5 0.48 10.8 1.3 2.8 2 1 0 2 2 2 1 Kinesin motor APG6 PF04111.7 ETO11451.1 - 0.0048 15.9 7.1 0.0048 15.9 4.9 1.7 2 0 0 2 2 2 1 Autophagy protein Apg6 DNase_II PF03265.10 ETO11451.1 - 0.012 14.6 0.6 0.012 14.6 0.4 2.6 2 1 1 3 3 3 0 Deoxyribonuclease II TMF_DNA_bd PF12329.3 ETO11451.1 - 0.015 15.0 9.4 0.015 15.0 6.5 3.4 3 1 1 4 4 3 0 TATA element modulatory factor 1 DNA binding COMP PF11598.3 ETO11451.1 - 0.02 14.9 2.5 0.54 10.3 1.8 2.6 1 1 0 1 1 1 0 Cartilage oligomeric matrix protein DKNYY PF13644.1 ETO11451.1 - 0.024 14.8 4.8 0.024 14.8 3.3 2.1 2 1 0 2 2 2 0 DKNYY family Enkurin PF13864.1 ETO11451.1 - 0.039 14.1 4.2 0.048 13.8 1.6 2.1 2 0 0 2 2 2 0 Calmodulin-binding V_ATPase_I PF01496.14 ETO11451.1 - 0.04 11.7 5.8 0.071 10.9 4.0 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Reo_sigmaC PF04582.7 ETO11451.1 - 0.048 12.8 2.0 0.085 12.0 1.4 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF2120 PF09893.4 ETO11451.1 - 0.082 12.8 1.5 5.9 6.8 0.2 2.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) Baculo_PEP_C PF04513.7 ETO11451.1 - 0.18 11.6 2.8 0.34 10.7 1.9 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tup_N PF08581.5 ETO11451.1 - 0.36 11.0 4.4 1.5 9.0 2.0 2.3 1 1 1 2 2 2 0 Tup N-terminal Bacillus_HBL PF05791.6 ETO11451.1 - 0.49 9.7 12.4 0.16 11.3 4.4 2.6 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) GLE1 PF07817.8 ETO11451.1 - 0.6 9.0 6.3 1.1 8.0 4.3 1.5 1 0 0 1 1 1 0 GLE1-like protein HSCB_C PF07743.8 ETO11451.1 - 0.78 10.2 6.0 0.46 10.9 1.8 2.3 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain HlyD PF00529.15 ETO11451.1 - 0.8 8.9 9.4 1.2 8.3 6.5 1.2 1 0 0 1 1 1 0 HlyD family secretion protein TPR_MLP1_2 PF07926.7 ETO11451.1 - 0.84 9.3 15.3 2.1 8.1 10.6 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Fzo_mitofusin PF04799.8 ETO11451.1 - 1 8.7 7.9 2.1 7.6 3.4 2.4 2 0 0 2 2 2 0 fzo-like conserved region DUF4201 PF13870.1 ETO11451.1 - 1.2 8.5 18.7 3 7.2 3.8 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) SlyX PF04102.7 ETO11451.1 - 1.5 9.2 7.0 3.3 8.1 0.6 3.1 1 1 2 3 3 3 0 SlyX IncA PF04156.9 ETO11451.1 - 1.8 8.1 13.3 5.8 6.4 8.0 2.3 2 1 0 2 2 2 0 IncA protein ING PF12998.2 ETO11451.1 - 1.8 8.8 10.8 8.7 6.6 6.2 2.7 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding COG2 PF06148.6 ETO11451.1 - 2.6 7.9 8.1 19 5.1 5.5 2.2 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin-6_N PF09177.6 ETO11451.1 - 2.7 8.4 11.1 1.5 9.2 0.2 3.1 2 2 2 4 4 2 0 Syntaxin 6, N-terminal DUF342 PF03961.8 ETO11451.1 - 3 6.1 12.3 2.1 6.6 7.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF342) PLRV_ORF5 PF01690.12 ETO11451.1 - 3.1 6.8 8.6 3.4 6.7 6.0 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Syntaxin PF00804.20 ETO11451.1 - 3.3 7.9 15.4 2.7 8.2 8.4 2.5 1 1 2 3 3 3 0 Syntaxin DUF2203 PF09969.4 ETO11451.1 - 4.4 7.5 7.6 11 6.3 4.4 2.3 2 1 0 2 2 1 0 Uncharacterized conserved protein (DUF2203) DUF4140 PF13600.1 ETO11451.1 - 5.3 7.5 10.7 5 7.6 1.4 3.1 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Nup54 PF13874.1 ETO11451.1 - 9.7 5.8 13.7 3.2 7.4 7.0 2.0 2 2 1 3 3 3 0 Nucleoporin complex subunit 54 SPRY PF00622.23 ETO11452.1 - 1.2e-06 28.5 0.3 2.7e-06 27.5 0.2 1.6 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 ETO11452.1 - 0.047 13.4 0.0 0.13 12.0 0.0 1.9 1 0 0 1 1 1 0 LisH Astro_capsid PF03115.9 ETO11452.1 - 0.14 10.3 1.7 0.21 9.7 1.2 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor BTK PF00779.14 ETO11453.1 - 1.5e-05 24.5 0.7 3e-05 23.5 0.5 1.6 1 1 0 1 1 1 1 BTK motif RNA_pol_3_Rpc31 PF11705.3 ETO11454.1 - 0.097 12.5 15.2 0.13 12.2 10.5 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TRAP_alpha PF03896.11 ETO11454.1 - 0.15 11.0 7.3 0.24 10.3 5.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Atrophin-1 PF03154.10 ETO11454.1 - 0.59 8.2 3.1 0.7 7.9 2.2 1.2 1 0 0 1 1 1 0 Atrophin-1 family RRN3 PF05327.6 ETO11454.1 - 1.5 6.8 10.1 2 6.3 7.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Daxx PF03344.10 ETO11454.1 - 1.7 7.0 17.0 2.1 6.7 11.8 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 ETO11454.1 - 3.3 5.5 17.7 4.2 5.1 12.3 1.2 1 0 0 1 1 1 0 Nop14-like family NPR3 PF03666.8 ETO11454.1 - 3.7 5.9 9.0 5.7 5.3 6.2 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Ycf1 PF05758.7 ETO11454.1 - 5 4.7 9.5 5.6 4.5 6.6 1.1 1 0 0 1 1 1 0 Ycf1 Pkinase PF00069.20 ETO11455.1 - 9.3e-21 74.1 0.1 9.3e-21 74.1 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO11455.1 - 9.7e-05 21.5 0.0 0.00025 20.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase DUF4519 PF15012.1 ETO11455.1 - 1.9 8.4 5.2 6.3 6.7 3.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) VWA PF00092.23 ETO11457.1 - 0.075 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain SWM_repeat PF13753.1 ETO11457.1 - 0.16 10.9 2.1 0.21 10.5 1.4 1.1 1 0 0 1 1 1 0 Putative flagellar system-associated repeat CAF-1_p150 PF11600.3 ETO11458.1 - 0.0065 15.8 11.1 0.0065 15.8 7.7 1.7 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal BSP_II PF05432.6 ETO11458.1 - 2 7.6 8.3 0.03 13.6 0.7 1.6 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) FAM176 PF14851.1 ETO11458.1 - 2.6 7.7 5.8 0.5 10.0 1.4 1.7 2 0 0 2 2 2 0 FAM176 family Pyr_redox_2 PF07992.9 ETO11459.1 - 4.9e-12 46.1 0.0 8e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UCH PF00443.24 ETO11460.1 - 1.7e-23 83.1 1.7 1.8e-23 82.9 0.2 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO11460.1 - 4.4e-11 42.7 0.6 1.6e-10 40.9 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase AAA_22 PF13401.1 ETO11460.1 - 0.005 16.9 0.0 0.016 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETO11460.1 - 0.0075 16.2 0.0 0.026 14.5 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 ETO11460.1 - 0.027 14.7 0.0 0.095 12.9 0.0 1.9 1 0 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.12 ETO11460.1 - 0.034 13.5 0.0 0.1 12.0 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 ETO11460.1 - 0.063 13.1 6.5 0.11 12.4 0.1 3.6 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 ETO11460.1 - 0.073 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Eapp_C PF10238.4 ETO11464.1 - 6.6 6.6 8.4 6.5 6.6 5.9 1.0 1 0 0 1 1 1 0 E2F-associated phosphoprotein SelP_N PF04592.9 ETO11468.1 - 0.033 13.5 7.4 0.042 13.2 5.1 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Neur_chan_memb PF02932.11 ETO11468.1 - 0.21 11.4 7.4 0.24 11.2 5.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.10 ETO11468.1 - 0.46 9.0 10.7 0.5 8.9 7.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1510 PF07423.6 ETO11468.1 - 1.1 8.6 20.6 1.3 8.3 14.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) MIP-T3 PF10243.4 ETO11468.1 - 1.5 7.1 34.9 1.8 6.9 24.2 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Effector_1 PF04518.7 ETO11468.1 - 2.6 6.9 10.9 3.2 6.6 7.6 1.1 1 0 0 1 1 1 0 Effector from type III secretion system GAGA_bind PF06217.7 ETO11468.1 - 3 7.7 21.1 3.9 7.3 14.7 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family HemX PF04375.9 ETO11468.1 - 6.8 5.1 10.5 9.1 4.7 7.3 1.1 1 0 0 1 1 1 0 HemX RNA_pol_Rpb1_5 PF04998.12 ETO11468.1 - 8 5.6 13.0 9 5.4 9.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 V_ATPase_I PF01496.14 ETO11468.1 - 9.5 3.9 11.0 9.1 3.9 7.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RRM_1 PF00076.17 ETO11469.1 - 3.2e-18 65.1 0.0 9.4e-18 63.6 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TLD PF07534.11 ETO11469.1 - 9.4e-14 51.5 0.0 1.2e-06 28.5 0.0 2.8 2 0 0 2 2 2 2 TLD RRM_6 PF14259.1 ETO11469.1 - 5.4e-13 48.7 0.0 1.5e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO11469.1 - 9e-09 35.0 0.0 1.8e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RabGAP-TBC PF00566.13 ETO11469.1 - 3.4e-05 23.4 0.1 3.4e-05 23.4 0.0 3.1 3 0 0 3 3 3 1 Rab-GTPase-TBC domain SprA-related PF12118.3 ETO11470.1 - 1 8.6 25.7 1.2 8.3 17.8 1.0 1 0 0 1 1 1 0 SprA-related family DUF1675 PF07897.6 ETO11470.1 - 1.9 8.2 21.6 2.2 8.0 14.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) BTV_NS2 PF04514.7 ETO11470.1 - 2.1 7.1 19.8 2.5 6.9 13.7 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Suf PF05843.9 ETO11470.1 - 5 6.7 13.5 5.8 6.5 9.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF420 PF04238.7 ETO11471.1 - 0.0021 18.0 1.6 0.0021 18.0 1.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF420) CitMHS PF03600.11 ETO11471.1 - 0.27 9.7 9.5 1.1 7.8 6.6 2.0 1 1 0 1 1 1 0 Citrate transporter WD40 PF00400.27 ETO11473.1 - 1.7e-73 240.1 12.2 2.3e-11 43.1 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO11473.1 - 2.2e-07 30.7 0.2 0.017 14.8 0.0 3.1 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO11473.1 - 7.7e-07 27.6 8.0 0.22 9.6 0.0 4.7 1 1 2 5 5 5 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO11473.1 - 0.00029 19.2 1.5 0.56 8.4 0.0 3.3 1 1 4 5 5 5 4 Cytochrome D1 heme domain Resistin PF06954.6 ETO11473.1 - 0.00078 19.6 0.2 1.8 8.8 0.0 4.0 2 1 2 4 4 4 1 Resistin PD40 PF07676.7 ETO11473.1 - 0.003 17.2 2.8 69 3.2 0.0 5.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF3601 PF12208.3 ETO11473.1 - 0.038 13.9 0.0 4 7.4 0.0 3.7 2 1 3 5 5 5 0 Domain of unknown function (DUF3601) RVT_thumb PF06817.9 ETO11473.1 - 0.07 12.7 0.1 4.2 7.0 0.0 2.5 2 0 0 2 2 2 0 Reverse transcriptase thumb domain Kelch_6 PF13964.1 ETO11474.1 - 2.2e-05 24.4 5.8 0.12 12.6 0.0 4.0 4 1 1 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO11474.1 - 0.00021 20.9 4.1 0.39 10.5 0.1 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO11474.1 - 0.0016 17.9 11.4 0.022 14.3 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO11474.1 - 0.055 13.6 2.2 6 7.1 0.0 3.3 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO11474.1 - 0.086 12.6 2.4 1.6 8.5 0.0 4.0 5 0 0 5 5 5 0 Galactose oxidase, central domain AAA_11 PF13086.1 ETO11474.1 - 0.2 11.1 7.4 0.23 11.0 1.4 2.2 2 0 0 2 2 2 0 AAA domain DUF3464 PF11947.3 ETO11474.1 - 0.22 11.0 4.3 0.84 9.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) TPR_2 PF07719.12 ETO11475.1 - 2.4e-05 23.9 4.3 0.014 15.2 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO11475.1 - 8.4e-05 22.1 0.4 8.4e-05 22.1 0.3 2.3 3 0 0 3 3 3 1 TPR repeat TPR_1 PF00515.23 ETO11475.1 - 0.00012 21.5 9.9 0.0059 16.1 0.2 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO11475.1 - 0.00059 19.8 2.2 0.058 13.6 0.0 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO11475.1 - 0.0023 17.8 7.8 0.013 15.4 0.1 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat EST1_DNA_bind PF10373.4 ETO11475.1 - 0.0076 15.5 0.4 0.031 13.4 0.0 1.9 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain Dot_icm_IcmQ PF09475.5 ETO11475.1 - 0.018 14.2 0.2 0.028 13.6 0.2 1.3 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) TPR_8 PF13181.1 ETO11475.1 - 0.025 14.3 0.2 0.025 14.3 0.2 4.7 5 1 1 6 6 6 0 Tetratricopeptide repeat WD40 PF00400.27 ETO11477.1 - 1.1e-68 224.8 24.8 6.6e-13 47.9 0.1 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO11477.1 - 3e-13 48.7 7.9 0.00035 18.8 0.1 5.4 2 1 4 6 6 6 5 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO11477.1 - 5.5e-08 32.7 7.5 0.00043 20.0 1.2 3.8 2 2 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A DUF1914 PF08932.5 ETO11477.1 - 5.1 7.1 10.5 2.1 8.4 0.2 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF1914) CPSF73-100_C PF11718.3 ETO11478.1 - 0.023 14.0 1.3 0.027 13.8 0.9 1.0 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term SurA_N_3 PF13624.1 ETO11478.1 - 0.055 13.4 0.5 0.066 13.1 0.3 1.1 1 0 0 1 1 1 0 SurA N-terminal domain DWNN PF08783.6 ETO11478.1 - 0.27 11.2 4.0 0.38 10.7 2.6 1.4 1 1 0 1 1 1 0 DWNN domain PNPase PF03726.9 ETO11478.1 - 1.5 9.1 5.2 1.4 9.1 0.3 2.1 1 1 1 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain zf-TRAF PF02176.13 ETO11479.1 - 4.3e-06 27.0 1.3 8.3e-06 26.0 0.9 1.5 1 0 0 1 1 1 1 TRAF-type zinc finger Ly49 PF08391.5 ETO11479.1 - 0.04 14.0 0.3 0.068 13.2 0.2 1.4 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Baculo_Y142 PF04913.7 ETO11479.1 - 0.059 11.7 0.7 0.082 11.2 0.5 1.1 1 0 0 1 1 1 0 Baculovirus Y142 protein Sina PF03145.11 ETO11479.1 - 0.15 11.7 2.0 0.63 9.6 0.0 2.1 1 1 1 2 2 2 0 Seven in absentia protein family Eapp_C PF10238.4 ETO11481.1 - 0.058 13.2 0.2 0.074 12.9 0.2 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein CENP-M PF11111.3 ETO11481.1 - 0.067 12.4 0.1 0.077 12.2 0.0 1.1 1 0 0 1 1 1 0 Centromere protein M (CENP-M) WD40 PF00400.27 ETO11482.1 - 1.2e-17 62.9 0.8 9.3e-06 25.3 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat EpoR_lig-bind PF09067.5 ETO11482.1 - 0.0012 18.8 1.6 0.097 12.6 0.3 2.8 3 0 0 3 3 3 2 Erythropoietin receptor, ligand binding WD40 PF00400.27 ETO11483.1 - 1.9e-14 52.8 7.7 0.0055 16.5 0.1 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat SAM_2 PF07647.12 ETO11483.1 - 4e-09 36.1 0.1 9.8e-09 34.9 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO11483.1 - 2.4e-08 34.0 0.1 4.9e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) MraZ PF02381.13 ETO11483.1 - 0.00098 18.8 0.0 0.0085 15.8 0.0 2.3 2 0 0 2 2 2 1 MraZ protein SAM_PNT PF02198.11 ETO11483.1 - 0.0026 17.4 0.0 0.013 15.2 0.0 2.0 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain Nucleoporin_N PF08801.6 ETO11483.1 - 0.003 16.3 3.2 0.0031 16.3 0.1 2.2 2 1 0 2 2 2 1 Nup133 N terminal like DUF3991 PF13154.1 ETO11483.1 - 0.056 13.6 0.0 1.8 8.8 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3991) DUF1681 PF07933.9 ETO11484.1 - 9.4e-16 57.7 1.4 4.6e-15 55.5 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1681) BSD PF03909.12 ETO11484.1 - 5e-09 35.7 0.5 5e-09 35.7 0.3 2.0 2 0 0 2 2 2 1 BSD domain Virulence_fact PF13769.1 ETO11486.1 - 0.025 14.4 0.3 0.11 12.3 0.2 2.1 1 0 0 1 1 1 0 Virulence factor FAD-SLDH PF12318.3 ETO11486.1 - 0.29 10.8 5.7 0.11 12.1 0.6 2.6 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase AChE_tetra PF08674.5 ETO11486.1 - 0.3 10.6 5.8 7.7 6.1 0.5 3.1 2 0 0 2 2 2 0 Acetylcholinesterase tetramerisation domain Myosin_tail_1 PF01576.14 ETO11487.1 - 0.017 12.8 39.2 0.025 12.3 27.2 1.2 1 0 0 1 1 1 0 Myosin tail CCDC144C PF14915.1 ETO11487.1 - 0.023 13.6 39.8 0.034 13.0 18.9 2.2 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region CENP-F_leu_zip PF10473.4 ETO11487.1 - 0.48 10.2 49.2 0.9 9.3 10.9 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CALCOCO1 PF07888.6 ETO11487.1 - 0.55 8.4 36.4 2.1 6.5 14.3 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Reo_sigmaC PF04582.7 ETO11487.1 - 0.71 8.9 9.0 0.14 11.3 0.8 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TMCO5 PF14992.1 ETO11487.1 - 0.85 8.7 39.7 0.19 10.8 1.8 2.1 1 1 1 2 2 2 0 TMCO5 family HOOK PF05622.7 ETO11487.1 - 5 4.7 39.7 12 3.5 27.5 1.5 1 1 0 1 1 1 0 HOOK protein Filament PF00038.16 ETO11487.1 - 6.9 6.0 40.6 16 4.8 28.0 1.6 1 1 0 1 1 1 0 Intermediate filament protein TPR_MLP1_2 PF07926.7 ETO11487.1 - 8.2 6.1 45.5 1.7 8.4 4.7 3.0 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein zf-RING_2 PF13639.1 ETO11489.1 - 4.2e-07 29.6 3.4 4.2e-07 29.6 2.4 7.2 5 3 1 6 6 6 1 Ring finger domain IBR PF01485.16 ETO11489.1 - 1.1e-05 25.2 5.7 1.1e-05 25.2 3.9 7.3 5 3 2 7 7 7 1 IBR domain zf-RING_5 PF14634.1 ETO11489.1 - 0.0021 17.7 1.3 0.0021 17.7 0.9 8.9 6 2 1 7 7 7 2 zinc-RING finger domain zf-C3HC4 PF00097.20 ETO11489.1 - 0.0036 16.9 0.7 0.0036 16.9 0.5 8.4 6 4 1 7 7 7 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO11489.1 - 0.0094 15.9 3.7 0.0094 15.9 2.6 8.9 6 2 2 8 8 8 2 Zinc finger, C3HC4 type (RING finger) Pex14_N PF04695.8 ETO11489.1 - 8.6 6.4 9.6 18 5.3 6.6 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region G-alpha PF00503.15 ETO11490.1 - 7.1e-91 304.7 21.0 1.3e-90 303.9 14.6 1.4 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO11490.1 - 8.2e-09 34.9 8.4 2.5e-05 23.6 0.1 4.2 3 1 1 4 4 4 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO11490.1 - 0.03 13.7 4.7 1.3 8.3 0.5 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Miro PF08477.8 ETO11490.1 - 0.056 13.9 1.0 10 6.6 0.0 3.0 3 0 0 3 3 3 0 Miro-like protein HEAT_2 PF13646.1 ETO11491.1 - 1.2e-17 63.9 0.1 3.3e-09 36.8 0.0 2.7 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 ETO11491.1 - 2.8e-15 54.9 0.0 0.019 15.0 0.0 5.2 5 0 0 5 5 5 4 HEAT repeat Cnd1 PF12717.2 ETO11491.1 - 3.2e-07 30.3 0.7 2.3e-05 24.3 0.4 2.4 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 ETO11491.1 - 6.7e-07 29.6 0.0 0.022 15.2 0.0 4.0 2 1 3 5 5 4 1 HEAT-like repeat TIP120 PF08623.5 ETO11491.1 - 6.8e-06 25.7 6.1 0.0082 15.7 0.6 3.6 1 1 4 5 5 5 4 TATA-binding protein interacting (TIP20) CLASP_N PF12348.3 ETO11491.1 - 1.1e-05 24.9 1.1 0.0052 16.1 0.0 2.4 1 1 1 2 2 2 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 ETO11491.1 - 3.5e-05 24.1 0.3 0.033 14.5 0.1 2.8 1 1 1 2 2 2 1 Vacuolar 14 Fab1-binding region DUF3554 PF12074.3 ETO11491.1 - 5.7e-05 22.7 2.4 0.00028 20.4 0.8 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF3554) ThylakoidFormat PF11264.3 ETO11491.1 - 0.0025 17.4 0.9 4.6 6.7 0.0 2.9 1 1 2 3 3 3 0 Thylakoid formation protein DUF2608 PF11019.3 ETO11491.1 - 0.0046 16.0 1.2 0.071 12.0 0.1 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF2608) Dopey_N PF04118.9 ETO11491.1 - 0.0056 15.4 0.4 0.46 9.2 0.0 2.8 1 1 2 3 3 3 1 Dopey, N-terminal XkdW PF09636.5 ETO11491.1 - 0.0076 16.1 7.9 1.6 8.6 0.1 3.9 2 1 2 4 4 4 1 XkdW protein HNH_5 PF14279.1 ETO11491.1 - 0.0086 16.0 6.3 0.25 11.3 0.2 3.5 1 1 2 4 4 4 1 HNH endonuclease UME PF08064.8 ETO11491.1 - 0.0087 16.0 1.0 2.3 8.2 0.0 3.4 1 1 2 3 3 3 1 UME (NUC010) domain DUF2435 PF10363.4 ETO11491.1 - 0.0099 15.7 0.5 2.6 8.0 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF2435) MOR2-PAG1_N PF14222.1 ETO11491.1 - 0.011 14.4 0.3 0.21 10.2 0.1 2.6 1 1 2 3 3 3 0 Cell morphogenesis N-terminal Toprim_2 PF13155.1 ETO11491.1 - 0.016 15.5 0.8 0.1 12.9 0.0 2.2 2 0 0 2 2 2 0 Toprim-like Npa1 PF11707.3 ETO11491.1 - 0.018 14.0 1.3 0.029 13.3 0.1 1.9 2 0 0 2 2 2 0 Ribosome 60S biogenesis N-terminal DUF445 PF04286.7 ETO11491.1 - 0.018 14.5 0.9 0.024 14.1 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) SPOC PF07744.8 ETO11491.1 - 0.024 15.1 0.1 0.1 13.0 0.0 2.0 1 1 1 2 2 2 0 SPOC domain Proteasom_PSMB PF10508.4 ETO11491.1 - 0.036 12.3 4.5 0.11 10.7 1.8 2.1 1 1 1 2 2 2 0 Proteasome non-ATPase 26S subunit CRM1_C PF08767.6 ETO11491.1 - 0.036 12.9 0.5 0.99 8.2 0.0 2.9 1 1 1 2 2 2 0 CRM1 C terminal TPR_21 PF09976.4 ETO11491.1 - 0.042 13.7 0.1 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat MOR2-PAG1_C PF14225.1 ETO11491.1 - 0.051 13.3 0.1 5.4 6.6 0.0 2.5 1 1 2 3 3 3 0 Cell morphogenesis C-terminal DNA_alkylation PF08713.6 ETO11491.1 - 0.088 12.3 0.2 2.9 7.3 0.1 2.2 1 1 1 2 2 2 0 DNA alkylation repair enzyme NLE PF08154.7 ETO11491.1 - 0.097 12.7 5.3 1.9 8.5 0.1 3.6 4 0 0 4 4 3 0 NLE (NUC135) domain Syntaphilin PF15290.1 ETO11491.1 - 0.1 12.0 6.2 0.39 10.1 0.5 2.8 2 1 2 4 4 4 0 Golgi-localised syntaxin-1-binding clamp MMS19_N PF14500.1 ETO11491.1 - 0.13 11.5 3.0 0.81 8.9 0.2 2.7 1 1 2 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II DUF3810 PF12725.2 ETO11491.1 - 0.19 10.5 0.6 1.1 8.0 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) DUF3349 PF11829.3 ETO11491.1 - 0.2 12.0 2.5 6.3 7.3 0.2 3.5 2 2 3 5 5 3 0 Protein of unknown function (DUF3349) DUF3510 PF12022.3 ETO11491.1 - 0.25 11.4 1.6 3 7.9 0.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3510) MSP7_C PF12948.2 ETO11491.1 - 0.26 11.5 5.0 6.4 7.0 0.3 2.5 2 1 0 2 2 2 0 MSP7-like protein C-terminal domain Gp-FAR-1 PF05823.7 ETO11491.1 - 0.59 10.0 4.9 2.9 7.8 0.0 2.5 2 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) CCDC-167 PF15188.1 ETO11491.1 - 0.9 9.5 6.5 17 5.4 0.1 3.9 4 0 0 4 4 4 0 Coiled-coil domain-containing protein 167 PRESAN PF09687.5 ETO11491.1 - 3.1 7.8 8.4 1 9.3 0.9 3.1 2 2 1 3 3 3 0 Plasmodium RESA N-terminal HEAT_EZ PF13513.1 ETO11492.1 - 0.0015 18.9 0.0 1.7 9.2 0.0 2.8 3 0 0 3 3 3 2 HEAT-like repeat zf-P11 PF03854.9 ETO11492.1 - 0.017 14.5 1.2 0.057 12.8 0.5 2.0 2 0 0 2 2 2 0 P-11 zinc finger Cnd1 PF12717.2 ETO11492.1 - 0.026 14.3 9.0 0.41 10.4 6.2 2.2 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 RNA_binding PF01877.12 ETO11492.1 - 0.032 14.2 1.0 1.4 8.9 0.2 3.0 1 1 1 3 3 3 0 RNA binding MOR2-PAG1_C PF14225.1 ETO11492.1 - 0.55 9.9 3.2 1.8 8.2 1.5 2.0 1 1 1 2 2 2 0 Cell morphogenesis C-terminal MatC_N PF07158.6 ETO11493.1 - 0.082 12.7 8.2 0.14 11.9 5.4 1.6 1 1 1 2 2 2 0 Dicarboxylate carrier protein MatC N-terminus FadA PF09403.5 ETO11494.1 - 7.1 6.6 8.1 3.7 7.5 0.4 2.2 1 1 0 2 2 2 0 Adhesion protein FadA His_Phos_1 PF00300.17 ETO11495.1 - 0.002 18.2 0.1 0.0038 17.3 0.1 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF1398 PF07166.6 ETO11496.1 - 0.1 12.4 4.3 0.9 9.4 2.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1398) TPR_12 PF13424.1 ETO11499.1 - 3.3e-27 94.2 2.9 1.1e-09 38.1 0.6 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO11499.1 - 2.7e-18 65.3 4.3 2.6e-11 42.9 0.6 2.5 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETO11499.1 - 2.9e-15 55.1 14.6 1.2e-05 24.6 0.1 4.8 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO11499.1 - 1.4e-12 47.0 0.0 0.00014 21.6 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO11499.1 - 2.2e-12 45.7 1.1 0.0092 15.7 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO11499.1 - 8e-10 37.7 11.6 0.0012 18.5 0.5 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO11499.1 - 1.9e-08 33.5 12.2 0.0015 18.3 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF4557 PF15101.1 ETO11499.1 - 0.11 12.3 9.3 0.17 11.6 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Med15 PF09606.5 ETO11499.1 - 0.17 10.0 23.9 0.22 9.6 16.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal UPF0560 PF10577.4 ETO11499.1 - 0.21 9.8 7.4 0.31 9.2 5.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TPR_17 PF13431.1 ETO11499.1 - 2.1 8.7 5.4 59 4.2 0.1 4.2 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF4175 PF13779.1 ETO11499.1 - 2.8 5.5 24.5 3.8 5.0 17.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Activator_LAG-3 PF11498.3 ETO11499.1 - 5.9 5.5 33.7 8.5 5.0 23.3 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 RNA_pol_Rbc25 PF08292.7 ETO11499.1 - 6.4 6.9 10.8 21 5.3 6.7 2.3 1 1 1 2 2 2 0 RNA polymerase III subunit Rpc25 WD40 PF00400.27 ETO11500.1 - 1e-05 25.2 0.4 0.00058 19.6 0.4 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat WD40 PF00400.27 ETO11501.1 - 5.4e-81 263.8 13.7 3.7e-13 48.7 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO11501.1 - 1.5e-16 60.6 0.4 3.9e-06 26.7 0.0 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO11501.1 - 1.1e-10 40.3 4.9 0.003 15.7 0.0 5.2 1 1 6 7 7 7 4 Nucleoporin Nup120/160 PD40 PF07676.7 ETO11501.1 - 5.2e-09 35.5 5.1 1.3 8.7 0.0 6.9 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO11501.1 - 4.1e-07 29.1 15.2 0.11 11.2 0.3 6.0 1 1 6 7 7 7 3 Nup133 N terminal like Coatomer_WDAD PF04053.9 ETO11501.1 - 4.2e-07 29.1 0.7 0.00096 18.0 0.1 2.1 1 1 1 2 2 2 2 Coatomer WD associated region Resistin PF06954.6 ETO11501.1 - 7.4e-06 26.1 0.0 9.3 6.6 0.0 5.2 1 1 4 5 5 5 1 Resistin PQQ_2 PF13360.1 ETO11501.1 - 0.00019 20.9 0.2 0.0086 15.5 0.2 2.7 1 1 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO11501.1 - 0.0051 15.1 0.3 0.97 7.6 0.0 2.7 1 1 1 3 3 3 2 Cytochrome D1 heme domain Gmad1 PF10647.4 ETO11501.1 - 0.0057 16.0 0.0 2 7.7 0.0 3.0 1 1 2 3 3 3 1 Lipoprotein LpqB beta-propeller domain Proteasome_A_N PF10584.4 ETO11501.1 - 0.019 14.2 12.0 1.5 8.2 0.1 5.8 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature DUF1258 PF06869.7 ETO11501.1 - 0.047 12.7 2.7 8 5.4 0.0 3.5 2 2 1 4 4 4 0 Protein of unknown function (DUF1258) DUF1870 PF08965.5 ETO11503.1 - 0.47 10.1 2.5 0.43 10.2 0.3 1.9 2 1 0 3 3 3 0 Domain of unknown function (DUF1870) SecA_DEAD PF07517.9 ETO11504.1 - 0.00014 21.3 2.1 0.0043 16.3 0.0 3.9 3 1 0 3 3 3 1 SecA DEAD-like domain FtsK_SpoIIIE PF01580.13 ETO11504.1 - 0.024 14.1 0.6 1 8.7 0.0 3.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family DUF2267 PF10025.4 ETO11504.1 - 0.07 13.1 0.1 0.54 10.3 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) TPR_11 PF13414.1 ETO11507.1 - 1.6e-14 53.3 2.9 1.2e-06 28.0 0.1 4.0 3 1 1 4 4 4 3 TPR repeat TPR_2 PF07719.12 ETO11507.1 - 4.4e-13 48.0 4.1 0.0014 18.3 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 ETO11507.1 - 2.6e-11 43.3 2.4 0.0015 18.4 0.0 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO11507.1 - 5e-10 39.5 0.6 5.3e-05 23.4 0.0 3.9 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO11507.1 - 8.3e-10 38.0 0.2 0.0048 17.0 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO11507.1 - 9.6e-10 37.6 5.9 0.084 12.5 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO11507.1 - 1.5e-09 37.5 0.1 0.038 14.6 0.0 5.0 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO11507.1 - 1.3e-08 35.2 0.0 5.9e-05 23.6 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat FAT PF02259.18 ETO11507.1 - 4.4e-08 32.5 2.3 0.0017 17.4 0.5 2.1 1 1 1 2 2 2 2 FAT domain TPR_8 PF13181.1 ETO11507.1 - 1.9e-06 27.2 10.9 0.39 10.6 0.0 5.3 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_20 PF14561.1 ETO11507.1 - 1e-05 25.5 0.0 0.00043 20.3 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO11507.1 - 7.4e-05 22.2 1.1 22 5.1 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 ETO11507.1 - 7.5e-05 22.7 3.8 0.015 15.4 1.0 2.8 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 ETO11507.1 - 0.0001 22.0 0.3 0.0014 18.3 0.1 2.4 2 1 1 3 3 3 2 Tetratricopeptide repeat RNA_bind PF08675.6 ETO11507.1 - 0.12 12.3 0.1 0.51 10.3 0.1 2.0 2 0 0 2 2 2 0 RNA binding domain TPR_11 PF13414.1 ETO11508.1 - 1.6e-06 27.6 9.4 0.0046 16.5 1.2 3.3 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 ETO11508.1 - 5.1e-06 25.9 6.8 0.0042 16.9 0.1 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO11508.1 - 0.00034 20.0 8.1 0.0046 16.4 0.3 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO11508.1 - 0.00048 19.9 4.6 0.083 12.8 0.0 3.7 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO11508.1 - 0.001 18.6 9.3 0.89 9.4 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO11508.1 - 0.04 14.6 0.1 13 6.5 0.0 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat Kinesin PF00225.18 ETO11508.1 - 0.045 12.4 0.8 0.087 11.5 0.6 1.4 1 0 0 1 1 1 0 Kinesin motor domain Ank_2 PF12796.2 ETO11508.1 - 0.046 14.0 0.1 0.19 12.0 0.1 2.0 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) DUF2949 PF11165.3 ETO11508.1 - 0.075 13.2 0.7 0.75 10.0 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2949) Nucleoplasmin PF03066.10 ETO11508.1 - 0.23 10.9 8.1 0.37 10.3 5.6 1.4 1 0 0 1 1 1 0 Nucleoplasmin TPR_17 PF13431.1 ETO11508.1 - 3.2 8.1 7.9 14 6.1 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Metallophos PF00149.23 ETO11510.1 - 0.021 14.2 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Imm24 PF15570.1 ETO11511.1 - 0.1 12.3 4.7 0.12 12.0 3.2 1.1 1 0 0 1 1 1 0 Immunity protein 24 Mur_ligase_M PF08245.7 ETO11512.1 - 3.8e-05 23.8 2.9 0.0024 17.9 0.1 2.7 2 1 0 2 2 2 2 Mur ligase middle domain Mur_ligase_C PF02875.16 ETO11512.1 - 0.024 14.6 0.0 0.059 13.4 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain FLO_LFY PF01698.11 ETO11513.1 - 0.028 13.2 0.9 0.027 13.3 0.6 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF3464 PF11947.3 ETO11513.1 - 0.046 13.1 0.3 0.055 12.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) AAA_23 PF13476.1 ETO11513.1 - 0.068 13.4 8.1 0.07 13.4 5.6 1.1 1 0 0 1 1 1 0 AAA domain Peroxin-13_N PF04088.8 ETO11513.1 - 0.14 12.1 1.4 0.16 11.9 0.9 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region BLVR PF06375.6 ETO11513.1 - 3.1 7.5 14.6 4.2 7.1 10.1 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Pox_Ag35 PF03286.9 ETO11513.1 - 4.9 6.6 13.4 5.9 6.3 9.3 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SMAP PF15477.1 ETO11513.1 - 5.9 7.2 12.1 15 5.9 8.4 1.7 1 1 0 1 1 1 0 Small acidic protein family NPR3 PF03666.8 ETO11513.1 - 9.3 4.6 8.1 12 4.3 5.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Ctr PF04145.10 ETO11514.1 - 0.0091 16.0 0.4 1.2 9.1 0.2 2.1 1 1 1 2 2 2 2 Ctr copper transporter family ATP_synt_I PF03899.10 ETO11514.1 - 0.015 15.4 0.4 0.037 14.1 0.3 1.7 1 0 0 1 1 1 0 ATP synthase I chain DUF3464 PF11947.3 ETO11514.1 - 0.11 11.9 1.5 0.16 11.4 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF106 PF01956.11 ETO11514.1 - 0.17 11.4 8.4 0.031 13.8 3.3 1.5 2 0 0 2 2 2 0 Integral membrane protein DUF106 TraP PF07296.6 ETO11516.1 - 0.063 12.2 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 TraP protein p450 PF00067.17 ETO11517.1 - 7.5e-40 136.8 0.1 2.1e-39 135.3 0.1 1.6 1 1 0 1 1 1 1 Cytochrome P450 DUF4504 PF14953.1 ETO11518.1 - 0.049 12.9 1.0 0.067 12.4 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4504) DUF1477 PF07346.6 ETO11520.1 - 0.023 14.7 2.7 2.6 8.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1477) DUF3922 PF13059.1 ETO11521.1 - 0.049 13.8 1.2 0.12 12.5 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3992) ERAP1_C PF11838.3 ETO11522.1 - 1.2e-07 31.2 0.2 4e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Syntaxin_2 PF14523.1 ETO11522.1 - 0.74 9.8 8.1 1.2 9.2 5.6 1.5 1 1 0 1 1 1 0 Syntaxin-like protein DUF1777 PF08648.7 ETO11523.1 - 0.00011 21.9 4.6 0.00012 21.9 3.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) Transformer PF06495.6 ETO11523.1 - 0.08 12.8 8.2 0.11 12.3 5.7 1.1 1 0 0 1 1 1 0 Fruit fly transformer protein DUF262 PF03235.9 ETO11523.1 - 0.6 10.0 7.9 0.69 9.8 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 TP53IP5 PF15331.1 ETO11523.1 - 0.71 9.7 16.1 0.81 9.5 11.1 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Hid1 PF12722.2 ETO11523.1 - 1 6.9 15.0 1.2 6.7 10.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Mitofilin PF09731.4 ETO11523.1 - 1.4 7.4 17.3 1.6 7.2 12.0 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Macoilin PF09726.4 ETO11523.1 - 3.7 5.7 17.8 3.8 5.6 12.3 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF1509 PF07420.6 ETO11523.1 - 3.8 6.7 9.7 5.6 6.1 6.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1509) RP-C_C PF11800.3 ETO11523.1 - 8.2 6.0 9.7 10 5.7 6.8 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region MIP-T3 PF10243.4 ETO11523.1 - 8.6 4.6 27.5 9.2 4.5 19.1 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 TNF PF00229.13 ETO11525.1 - 0.72 9.4 3.8 4.8 6.7 0.2 3.2 3 1 0 3 3 3 0 TNF(Tumour Necrosis Factor) family SdpI PF13630.1 ETO11526.1 - 3.5 7.3 7.9 0.73 9.5 2.7 1.9 1 1 1 2 2 2 0 SdpI/YhfL protein family DNA_RNApol_7kD PF03604.8 ETO11528.1 - 6.3e-12 44.7 3.9 1.3e-11 43.7 2.7 1.6 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit Rad60-SLD PF11976.3 ETO11528.1 - 1.7e-08 33.9 2.3 0.015 14.9 0.0 4.4 4 0 0 4 4 4 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 ETO11528.1 - 4.4e-07 29.2 1.8 0.02 14.2 0.0 4.3 4 0 0 4 4 4 2 Ubiquitin family HypA PF01155.14 ETO11528.1 - 0.064 12.9 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Prok-RING_1 PF14446.1 ETO11528.1 - 0.068 12.9 2.7 0.14 11.9 1.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DZR PF12773.2 ETO11528.1 - 0.076 12.8 0.3 0.16 11.7 0.2 1.5 1 0 0 1 1 1 0 Double zinc ribbon TUG-UBL1 PF11470.3 ETO11528.1 - 0.083 12.8 1.4 0.87 9.5 0.2 2.6 2 0 0 2 2 2 0 GLUT4 regulating protein TUG FAM176 PF14851.1 ETO11528.1 - 2.3 7.8 6.3 5.7 6.6 1.3 2.4 2 0 0 2 2 2 0 FAM176 family SNAP-25 PF00835.14 ETO11528.1 - 4 8.2 7.0 2.7 8.8 0.1 2.6 2 0 0 2 2 2 0 SNAP-25 family Kelch_1 PF01344.20 ETO11529.1 - 8.7e-06 25.1 0.3 0.02 14.3 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO11529.1 - 3.2e-05 23.9 0.5 1.5 9.0 0.0 4.5 3 1 1 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO11529.1 - 0.00019 21.1 0.1 1.1 9.0 0.0 3.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO11529.1 - 0.0037 17.3 0.0 0.26 11.5 0.0 3.4 4 0 0 4 4 4 1 Galactose oxidase, central domain Pkinase PF00069.20 ETO11530.1 - 0.0021 17.2 0.2 0.003 16.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 ETO11531.1 - 1.4e-11 43.8 4.4 5.3e-11 41.9 0.1 3.3 3 1 0 3 3 3 1 WD domain, G-beta repeat DnaJ PF00226.26 ETO11532.1 - 0.00055 19.6 0.6 0.0019 17.9 0.1 2.2 2 0 0 2 2 2 1 DnaJ domain DUF3680 PF12441.3 ETO11532.1 - 0.019 14.8 1.7 0.045 13.6 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3680) Peptidase_C37 PF05416.7 ETO11532.1 - 1 7.5 4.8 1.3 7.2 3.3 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase RasGEF PF00617.14 ETO11535.1 - 0.0008 19.1 1.1 0.002 17.8 0.7 1.6 1 0 0 1 1 1 1 RasGEF domain mRNA_triPase PF02940.10 ETO11536.1 - 1.3e-16 60.9 9.5 7.1e-16 58.6 3.6 2.1 2 0 0 2 2 2 2 mRNA capping enzyme, beta chain EpsG PF14897.1 ETO11536.1 - 0.024 13.5 4.8 0.038 12.9 3.3 1.2 1 0 0 1 1 1 0 EpsG family Histone PF00125.19 ETO11537.1 - 6.3e-16 58.2 0.1 1.2e-15 57.3 0.1 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 ETO11537.1 - 0.012 15.6 1.0 0.021 14.8 0.1 1.9 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Actin PF00022.14 ETO11538.1 - 1.5e-63 214.5 0.0 1.7e-63 214.4 0.0 1.0 1 0 0 1 1 1 1 Actin DUF912 PF06024.7 ETO11539.1 - 0.058 13.4 0.3 0.097 12.7 0.2 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PBP1_TM PF14812.1 ETO11539.1 - 3.3 8.0 6.0 1.4 9.2 1.6 2.2 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cytochrom_B562 PF07361.6 ETO11541.1 - 0.00082 19.7 0.4 0.0066 16.8 0.1 2.5 2 0 0 2 2 2 1 Cytochrome b562 Ribosomal_L17 PF01196.14 ETO11541.1 - 0.065 13.8 0.0 17 6.0 0.0 2.7 2 0 0 2 2 2 0 Ribosomal protein L17 NDUF_B6 PF09782.4 ETO11542.1 - 0.1 12.4 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit GTP_EFTU_D2 PF03144.20 ETO11544.1 - 9.5e-08 32.0 0.0 2.7e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 ETO11544.1 - 0.0027 17.3 0.0 0.0068 16.0 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu domain 4 DUF2682 PF10909.3 ETO11544.1 - 0.047 13.9 0.1 0.072 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2682) Peptidase_C14 PF00656.17 ETO11545.1 - 0.00011 21.9 0.0 0.00012 21.8 0.0 1.2 1 0 0 1 1 1 1 Caspase domain WD40 PF00400.27 ETO11546.1 - 2e-73 239.8 24.1 1.1e-12 47.2 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO11546.1 - 7.3e-08 30.9 4.6 0.073 11.2 0.2 4.2 1 1 1 3 3 3 3 Nucleoporin Nup120/160 DUF1258 PF06869.7 ETO11546.1 - 0.00022 20.3 1.1 0.06 12.4 0.2 3.4 2 2 2 4 4 4 1 Protein of unknown function (DUF1258) Proteasome_A_N PF10584.4 ETO11546.1 - 0.00052 19.2 3.2 24 4.3 0.0 5.7 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature Cytochrom_D1 PF02239.11 ETO11546.1 - 0.0043 15.4 0.6 1.2 7.3 0.0 3.0 2 1 1 3 3 3 1 Cytochrome D1 heme domain Resistin PF06954.6 ETO11546.1 - 0.011 16.0 0.6 37 4.6 0.0 4.3 2 2 2 4 4 4 0 Resistin PD40 PF07676.7 ETO11546.1 - 0.015 14.9 6.6 29 4.4 0.1 5.9 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat DUF1938 PF09153.5 ETO11546.1 - 0.088 12.6 0.1 0.69 9.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1938) PLD_C PF12357.3 ETO11546.1 - 0.14 11.7 0.3 8.1 6.0 0.0 3.2 4 0 0 4 4 4 0 Phospholipase D C terminal WD40 PF00400.27 ETO11548.1 - 9.8e-39 129.8 11.9 1.3e-07 31.1 0.0 5.6 5 1 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO11548.1 - 5.7e-05 21.4 0.0 0.11 10.6 0.0 3.3 3 1 0 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO11548.1 - 0.0056 16.4 0.2 2.2 7.9 0.0 3.1 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A YniB PF14002.1 ETO11549.1 - 0.0017 17.7 1.1 0.0035 16.8 0.8 1.5 1 0 0 1 1 1 1 YniB-like protein Tetraspannin PF00335.15 ETO11549.1 - 0.0076 15.5 0.4 0.62 9.3 0.0 2.2 2 0 0 2 2 2 2 Tetraspanin family Neur_chan_memb PF02932.11 ETO11549.1 - 0.059 13.2 1.0 0.12 12.2 0.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pex24p PF06398.6 ETO11549.1 - 0.073 11.8 0.8 0.14 10.9 0.1 1.7 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin F-actin_cap_A PF01267.12 ETO11551.1 - 7.1e-45 153.1 0.6 1.2e-34 119.6 0.0 2.7 2 1 0 2 2 2 2 F-actin capping protein alpha subunit MORN_2 PF07661.8 ETO11551.1 - 0.14 12.3 1.9 31 5.0 0.2 4.0 3 1 1 4 4 4 0 MORN repeat variant Herpes_BLRF2 PF05812.7 ETO11552.1 - 0.0013 18.4 20.4 0.0054 16.5 4.5 3.9 3 2 1 4 4 4 2 Herpesvirus BLRF2 protein PilJ PF13675.1 ETO11552.1 - 0.54 10.5 13.6 0.29 11.4 0.9 3.7 2 1 2 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term Reo_sigmaC PF04582.7 ETO11552.1 - 0.65 9.1 11.3 0.19 10.8 2.8 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein LRR_6 PF13516.1 ETO11552.1 - 3.8 7.8 5.9 2.6 8.3 0.1 3.4 4 0 0 4 4 4 0 Leucine Rich repeat Zea_mays_MuDR PF05928.6 ETO11554.1 - 0.013 14.9 1.3 0.015 14.7 0.9 1.1 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) Y_phosphatase3 PF13350.1 ETO11554.1 - 0.14 12.3 3.6 0.23 11.7 2.5 1.5 1 1 0 1 1 1 0 Tyrosine phosphatase family IF-2B PF01008.12 ETO11554.1 - 0.37 9.7 6.8 0.41 9.5 4.7 1.1 1 0 0 1 1 1 0 Initiation factor 2 subunit family Gly_radical PF01228.16 ETO11554.1 - 0.8 10.0 4.0 0.92 9.8 2.4 1.4 1 1 0 1 1 1 0 Glycine radical PMC2NT PF08066.7 ETO11554.1 - 2.3 8.5 7.6 0.26 11.5 1.1 2.2 1 1 1 2 2 2 0 PMC2NT (NUC016) domain Atg14 PF10186.4 ETO11554.1 - 3.7 6.4 11.4 4.6 6.0 7.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 ETO11554.1 - 5.6 4.6 11.1 6.7 4.4 7.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Trehalase PF01204.13 ETO11554.1 - 5.7 5.4 9.2 6.5 5.2 6.3 1.0 1 0 0 1 1 1 0 Trehalase CDC45 PF02724.9 ETO11555.1 - 0.11 10.5 13.2 0.13 10.2 9.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.11 ETO11555.1 - 0.32 10.8 13.6 0.34 10.7 9.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Mem_trans PF03547.13 ETO11555.1 - 0.67 8.1 6.0 0.75 8.0 4.2 1.2 1 0 0 1 1 1 0 Membrane transport protein NPR3 PF03666.8 ETO11555.1 - 0.67 8.4 16.4 0.88 8.0 11.4 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 UPF0560 PF10577.4 ETO11555.1 - 0.79 7.9 13.5 0.84 7.8 9.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Hid1 PF12722.2 ETO11555.1 - 1.2 6.7 15.0 1.1 6.8 10.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1510 PF07423.6 ETO11555.1 - 1.4 8.2 20.0 1.9 7.8 13.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SID-1_RNA_chan PF13965.1 ETO11555.1 - 2.6 6.1 6.4 3 5.9 4.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Ndc1_Nup PF09531.5 ETO11555.1 - 2.8 6.2 12.2 3.1 6.1 8.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4407 PF14362.1 ETO11555.1 - 3.3 6.5 11.2 4.8 6.0 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MIP-T3 PF10243.4 ETO11555.1 - 3.9 5.8 36.0 4.2 5.7 25.0 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Presenilin PF01080.12 ETO11555.1 - 7.6 5.2 6.1 9.1 4.9 4.3 1.2 1 0 0 1 1 1 0 Presenilin FYDLN_acid PF09538.5 ETO11555.1 - 8.3 7.0 13.6 55 4.4 9.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Paramyxo_ncap PF00973.14 ETO11555.1 - 9.8 4.7 12.4 13 4.3 8.6 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CUE PF02845.11 ETO11556.1 - 0.014 14.8 0.1 5 6.7 0.0 2.7 2 0 0 2 2 2 0 CUE domain Pex16 PF08610.5 ETO11556.1 - 3.1 6.7 7.4 1.2 8.0 3.3 1.5 1 1 0 2 2 2 0 Peroxisomal membrane protein (Pex16) Guanylate_cyc PF00211.15 ETO11557.1 - 0.0043 16.4 0.0 0.0086 15.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PX PF00787.19 ETO11558.1 - 0.0034 17.1 0.8 0.0047 16.7 0.6 1.5 1 1 0 1 1 1 1 PX domain Mito_carr PF00153.22 ETO11560.1 - 3e-14 52.4 1.0 5.4e-14 51.6 0.7 1.5 1 0 0 1 1 1 1 Mitochondrial carrier protein Tropomyosin_1 PF12718.2 ETO11561.1 - 8e-05 22.5 9.9 8e-05 22.5 6.9 3.3 4 0 0 4 4 4 2 Tropomyosin like EAP30 PF04157.11 ETO11561.1 - 0.0018 17.4 1.2 0.0018 17.4 0.8 3.6 3 1 1 4 4 4 1 EAP30/Vps36 family DUF3782 PF12644.2 ETO11561.1 - 0.0034 17.1 0.1 0.74 9.6 0.0 3.3 3 1 0 3 3 3 1 Protein of unknown function (DUF3782) B-block_TFIIIC PF04182.7 ETO11561.1 - 0.05 13.4 1.1 0.17 11.7 0.8 1.9 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC KID PF02524.9 ETO11561.1 - 3.2 8.2 8.6 27 5.4 1.5 4.5 3 0 0 3 3 3 0 KID repeat KH_2 PF07650.12 ETO11561.1 - 3.6 7.2 15.8 0.086 12.4 3.1 3.1 3 0 0 3 3 3 0 KH domain DUF4140 PF13600.1 ETO11561.1 - 7.5 7.0 6.4 18 5.8 0.9 2.9 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Vac_Fusion PF02346.11 ETO11561.1 - 7.8 6.0 12.1 6 6.3 0.3 5.3 6 0 0 6 6 6 0 Chordopoxvirus fusion protein zf-Paramyx-P PF13008.2 ETO11562.1 - 0.063 12.4 1.0 0.14 11.3 0.7 1.6 1 0 0 1 1 1 0 Zinc-binding domain of Paramyxoviridae V protein Nup54 PF13874.1 ETO11564.1 - 0.007 16.0 12.9 0.049 13.2 0.2 2.7 2 0 0 2 2 2 2 Nucleoporin complex subunit 54 Herpes_UL25 PF01499.11 ETO11564.1 - 0.096 10.9 8.1 0.013 13.8 0.9 2.1 2 0 0 2 2 2 0 Herpesvirus UL25 family RNase_H PF00075.19 ETO11567.1 - 4.3e-15 56.2 0.0 2.1e-14 53.9 0.0 2.1 1 1 0 1 1 1 1 RNase H DNA_pol_B_2 PF03175.8 ETO11568.1 - 0.04 12.6 0.2 0.053 12.1 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral RVT_1 PF00078.22 ETO11569.1 - 9.5e-24 83.9 0.2 1.6e-23 83.2 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Raptor_N PF14538.1 ETO11570.1 - 0.047 13.5 2.5 0.058 13.2 1.7 1.1 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain Vfa1 PF08432.5 ETO11570.1 - 0.28 11.1 15.6 0.29 11.1 10.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1168 PF06658.7 ETO11570.1 - 1 8.8 23.5 1.4 8.4 16.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Mgr1 PF08602.5 ETO11570.1 - 1.5 7.7 9.9 1.6 7.6 6.9 1.0 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit OmpH PF03938.9 ETO11570.1 - 1.7 8.5 8.9 1.8 8.4 6.1 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Peptidase_S49_N PF08496.5 ETO11570.1 - 1.8 8.3 15.7 2.5 7.9 10.9 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CAF-1_p150 PF11600.3 ETO11570.1 - 3.1 7.1 25.7 3.7 6.8 17.8 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Virul_fac_BrkB PF03631.10 ETO11571.1 - 0.02 14.2 0.2 0.025 13.9 0.1 1.1 1 0 0 1 1 1 0 Virulence factor BrkB DUF1539 PF07560.6 ETO11572.1 - 0.036 13.9 1.3 3.3 7.5 0.0 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) Glyco_transf_90 PF05686.7 ETO11573.1 - 2.7e-28 98.7 0.9 7.5e-28 97.3 0.6 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 ETO11573.1 - 9.1e-05 22.6 0.0 0.00018 21.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF1676 PF07898.8 ETO11573.1 - 0.14 12.4 0.0 0.52 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Rep_3 PF01051.16 ETO11575.1 - 0.0049 16.5 0.2 0.0049 16.5 0.1 2.4 2 1 0 2 2 2 1 Initiator Replication protein DUF3644 PF12358.3 ETO11575.1 - 0.028 14.6 0.1 0.073 13.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3644) PCI PF01399.22 ETO11575.1 - 0.063 13.5 0.5 0.12 12.6 0.4 1.6 1 1 0 1 1 1 0 PCI domain Folliculin PF11704.3 ETO11577.1 - 0.13 11.8 0.1 0.13 11.8 0.0 2.7 2 1 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport zinc-ribbons_6 PF07191.7 ETO11578.1 - 0.49 10.2 7.0 0.9 9.3 4.9 1.4 1 0 0 1 1 1 0 zinc-ribbons WD40 PF00400.27 ETO11579.1 - 1.1e-34 117.0 2.3 9.8e-10 37.9 0.1 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO11579.1 - 8.2e-06 24.2 1.4 0.00058 18.1 0.1 2.6 1 1 1 3 3 3 1 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO11579.1 - 1.7e-05 24.6 0.4 3.1e-05 23.7 0.3 1.4 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 ETO11579.1 - 7.4e-05 21.6 0.3 0.034 12.9 0.0 2.2 1 1 1 2 2 2 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO11579.1 - 0.0029 15.9 0.0 0.27 9.4 0.0 2.1 1 1 1 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.7 ETO11579.1 - 0.02 14.5 1.9 2.1 8.1 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat B_lectin PF01453.19 ETO11579.1 - 0.05 13.4 0.3 0.11 12.3 0.2 1.7 1 1 0 1 1 1 0 D-mannose binding lectin DUF1977 PF09320.6 ETO11580.1 - 0.073 13.3 5.3 0.09 13.0 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1977) TRH PF05438.7 ETO11580.1 - 0.15 11.4 6.0 0.15 11.3 4.1 1.0 1 0 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) DUF2407 PF10302.4 ETO11580.1 - 4.1 7.6 6.1 4.7 7.4 4.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF106 PF01956.11 ETO11580.1 - 8.6 5.8 13.2 9.7 5.6 9.1 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 MBOAT PF03062.14 ETO11581.1 - 1.8e-07 30.6 35.9 1.2e-06 27.9 24.9 2.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Actin PF00022.14 ETO11582.1 - 1.5e-115 385.8 0.0 1.8e-115 385.5 0.0 1.0 1 0 0 1 1 1 1 Actin Cache_1 PF02743.13 ETO11582.1 - 0.009 15.5 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 Cache domain BPL_LplA_LipB PF03099.14 ETO11584.1 - 1.5e-16 60.5 0.0 2.9e-16 59.6 0.0 1.5 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Cellulose_synt PF03552.9 ETO11584.1 - 0.12 10.5 0.2 0.23 9.7 0.1 1.4 1 0 0 1 1 1 0 Cellulose synthase PAP2_C PF14360.1 ETO11585.1 - 0.0087 16.3 0.1 0.013 15.7 0.1 1.2 1 0 0 1 1 1 1 PAP2 superfamily C-terminal Bac_small_YrzI PF09501.5 ETO11585.1 - 0.39 10.6 1.7 0.71 9.8 1.2 1.4 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) RyR PF02026.11 ETO11586.1 - 1.4e-09 37.8 0.0 3.5e-08 33.3 0.0 2.0 2 0 0 2 2 2 2 RyR domain Ank_3 PF13606.1 ETO11587.1 - 1.3e-10 40.4 1.1 7.2e-06 25.7 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 ETO11587.1 - 1.3e-10 41.4 0.3 3.2e-09 37.0 0.1 2.9 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO11587.1 - 2.6e-10 39.5 0.1 4e-05 23.2 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 ETO11587.1 - 7e-10 38.8 0.3 5e-06 26.5 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO11587.1 - 5.8e-09 36.2 0.6 2.7e-08 34.0 0.2 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Menin PF05053.8 ETO11588.1 - 0.059 11.5 0.0 0.079 11.1 0.0 1.1 1 0 0 1 1 1 0 Menin DUF2951 PF11166.3 ETO11589.1 - 0.17 11.7 4.3 0.33 10.8 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) DARPP-32 PF05395.7 ETO11590.1 - 0.75 9.9 9.4 1.7 8.7 6.5 1.6 1 1 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 DUF2175 PF09943.4 ETO11590.1 - 7 6.7 10.2 1.8 8.6 3.9 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) SAM_1 PF00536.25 ETO11591.1 - 0.001 19.1 0.3 0.0035 17.4 0.1 1.9 1 1 1 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO11591.1 - 0.052 13.3 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF2414 PF10309.4 ETO11591.1 - 0.13 11.9 0.1 0.13 11.9 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2414) CD20 PF04103.10 ETO11592.1 - 0.035 14.0 0.1 0.1 12.5 0.1 1.8 1 0 0 1 1 1 0 CD20-like family WD40 PF00400.27 ETO11594.1 - 0.00026 20.7 0.0 0.42 10.5 0.0 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 ETO11594.1 - 0.033 13.9 0.1 9.1 6.1 0.0 2.3 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region GLE1 PF07817.8 ETO11595.1 - 0.011 14.6 0.1 0.014 14.3 0.1 1.1 1 0 0 1 1 1 0 GLE1-like protein DUF924 PF06041.6 ETO11595.1 - 0.091 12.4 0.1 0.1 12.3 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF924) LigT_PEase PF02834.11 ETO11596.1 - 8.5e-07 28.8 0.2 3.3e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 LigT like Phosphoesterase FMO-like PF00743.14 ETO11597.1 - 9.1e-08 30.7 0.0 1.4e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like DUF1684 PF07920.6 ETO11598.1 - 0.014 15.2 0.1 0.036 13.9 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1684) zf-TRAF PF02176.13 ETO11600.1 - 9.6e-07 29.0 2.1 9.6e-07 29.0 1.4 2.3 3 0 0 3 3 3 1 TRAF-type zinc finger DUF723 PF05265.8 ETO11600.1 - 0.035 13.8 3.2 1.5 8.6 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF723) zf-C3HC4_4 PF15227.1 ETO11600.1 - 0.067 13.0 1.2 0.067 13.0 0.8 2.9 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING Redoxin PF08534.5 ETO11600.1 - 0.13 11.7 0.4 5.4 6.5 0.0 2.1 1 1 1 2 2 2 0 Redoxin Atg14 PF10186.4 ETO11600.1 - 1.9 7.3 12.5 3 6.7 8.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 WD40 PF00400.27 ETO11601.1 - 1.8e-129 417.5 34.2 8.5e-12 44.4 0.1 12.3 12 0 0 12 12 12 12 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO11601.1 - 2.8e-06 25.9 7.6 0.39 8.9 0.0 5.1 3 2 1 5 5 5 4 Cytochrome D1 heme domain Pentapeptide PF00805.17 ETO11601.1 - 4.2e-06 25.8 0.5 1.3e-05 24.3 0.3 1.8 1 1 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO11601.1 - 6.1e-06 25.9 1.0 1.7e-05 24.5 0.3 2.0 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 ETO11601.1 - 0.00013 21.7 0.4 0.00073 19.3 0.3 2.4 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) PD40 PF07676.7 ETO11601.1 - 2.1 8.0 9.9 65 3.3 0.0 5.9 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat NACHT PF05729.7 ETO11602.1 - 2.9e-10 40.0 0.0 5.8e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO11602.1 - 2.5e-06 27.8 0.1 2.5e-06 27.8 0.1 2.9 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 ETO11602.1 - 3.8e-05 23.8 0.0 0.00022 21.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ETO11602.1 - 0.00011 22.9 1.1 0.00061 20.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 ETO11602.1 - 0.0019 17.8 0.0 0.013 15.1 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 ATP_bind_2 PF03668.10 ETO11602.1 - 0.011 14.7 0.1 0.028 13.4 0.0 1.7 2 0 0 2 2 2 0 P-loop ATPase protein family AAA_33 PF13671.1 ETO11602.1 - 0.022 14.6 0.0 0.047 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 ETO11602.1 - 0.025 14.8 0.0 0.064 13.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETO11602.1 - 0.027 14.4 0.1 0.43 10.5 0.0 2.3 1 1 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 ETO11602.1 - 0.053 13.7 1.4 0.4 10.8 0.0 2.6 1 1 1 2 2 2 0 RNA helicase Zeta_toxin PF06414.7 ETO11602.1 - 0.058 12.4 0.0 0.17 10.9 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_5 PF07728.9 ETO11602.1 - 0.069 12.8 0.0 0.2 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 ETO11602.1 - 0.084 13.1 0.3 0.31 11.3 0.2 2.0 1 1 0 1 1 1 0 ABC transporter F-box-like PF12937.2 ETO11604.1 - 4.9e-07 29.3 0.5 1.6e-06 27.7 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 ETO11604.1 - 1.4e-06 27.8 0.0 9.2e-06 25.1 0.0 2.3 2 1 1 3 3 3 1 F-box domain Arch_flagellin PF01917.11 ETO11604.1 - 0.15 11.6 2.7 0.41 10.2 2.1 1.6 1 1 0 1 1 1 0 Archaebacterial flagellin Ank_5 PF13857.1 ETO11605.1 - 1.7e-10 40.8 0.2 1.4e-05 25.2 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO11605.1 - 1.8e-09 37.8 0.2 6.1e-09 36.1 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO11605.1 - 8.1e-09 35.7 0.4 0.001 19.5 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO11605.1 - 5.1e-06 26.2 0.0 0.0078 16.3 0.0 3.3 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.25 ETO11605.1 - 1.9e-05 24.2 0.2 0.037 13.8 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat Arm PF00514.18 ETO11605.1 - 0.003 17.3 0.2 0.003 17.3 0.1 3.5 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Peptidase_S49 PF01343.13 ETO11606.1 - 7.8e-12 45.2 0.0 1.4e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S49 Poly_export PF02563.11 ETO11606.1 - 0.073 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis/export protein CemA PF03040.9 ETO11607.1 - 0.04 13.5 4.3 0.046 13.3 3.0 1.0 1 0 0 1 1 1 0 CemA family BAR_3_WASP_bdg PF10456.4 ETO11607.1 - 0.056 12.7 0.2 0.081 12.1 0.1 1.4 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein CLASP_N PF12348.3 ETO11608.1 - 5.3e-07 29.2 3.7 0.0044 16.4 0.7 2.5 2 0 0 2 2 2 2 CLASP N terminal HSP90 PF00183.13 ETO11610.1 - 0.0022 16.4 9.6 0.0029 16.0 6.6 1.1 1 0 0 1 1 1 1 Hsp90 protein Virul_Fac PF10139.4 ETO11610.1 - 0.013 13.5 0.4 0.035 12.0 0.3 1.6 2 0 0 2 2 2 0 Putative bacterial virulence factor Sigma70_ner PF04546.8 ETO11610.1 - 0.054 13.0 6.8 0.033 13.8 2.5 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF740 PF05340.7 ETO11610.1 - 0.22 9.8 5.2 0.22 9.8 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) CDC45 PF02724.9 ETO11610.1 - 0.23 9.4 5.9 0.31 9.0 4.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Sec62 PF03839.11 ETO11610.1 - 5.5 6.3 12.1 1.7 8.0 6.1 1.7 2 0 0 2 2 2 0 Translocation protein Sec62 YqfQ PF14181.1 ETO11610.1 - 6.2 6.8 9.1 12 5.8 6.3 1.4 1 0 0 1 1 1 0 YqfQ-like protein SNARE PF05739.14 ETO11611.1 - 3.6e-11 42.5 12.0 4.3e-11 42.3 3.4 2.7 2 0 0 2 2 2 1 SNARE domain Daxx PF03344.10 ETO11611.1 - 0.014 13.9 24.1 0.025 13.0 16.7 1.3 1 0 0 1 1 1 0 Daxx Family TRAP-delta PF05404.7 ETO11611.1 - 0.018 14.5 0.1 0.045 13.2 0.0 1.6 1 0 0 1 1 1 0 Translocon-associated protein, delta subunit precursor (TRAP-delta) DUF3671 PF12420.3 ETO11611.1 - 0.018 14.9 0.6 0.018 14.9 0.4 4.2 3 1 1 4 4 4 0 Protein of unknown function DUF2457 PF10446.4 ETO11611.1 - 4.7 5.8 23.4 7.9 5.0 16.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Kinetochor_Ybp2 PF08568.5 ETO11612.1 - 1.7e-05 23.3 4.4 2.6e-05 22.6 3.0 1.5 1 1 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin WD40 PF00400.27 ETO11613.1 - 4.4e-27 92.9 5.8 1.1e-09 37.7 0.0 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO11613.1 - 0.00036 18.7 0.2 0.096 10.8 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 AAA_22 PF13401.1 ETO11614.1 - 0.0024 18.0 1.5 0.096 12.8 0.3 3.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETO11614.1 - 0.0041 17.1 0.0 0.009 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Miro PF08477.8 ETO11614.1 - 0.051 14.0 7.0 0.14 12.6 0.0 4.1 3 1 0 3 3 3 0 Miro-like protein AAA_29 PF13555.1 ETO11614.1 - 0.059 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 ETO11614.1 - 0.062 13.4 7.1 0.31 11.2 0.0 4.6 5 0 0 5 5 5 0 RNA helicase DUF87 PF01935.12 ETO11614.1 - 0.092 12.5 0.0 0.092 12.5 0.0 3.7 3 2 0 3 3 3 0 Domain of unknown function DUF87 AAA_16 PF13191.1 ETO11615.1 - 7.9e-05 22.7 0.0 0.00015 21.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 ETO11615.1 - 0.00045 20.3 2.9 0.0082 16.2 0.4 3.1 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.1 ETO11615.1 - 0.016 14.7 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 ETO11615.1 - 0.074 13.2 4.5 0.27 11.4 0.0 3.9 2 2 1 3 3 3 0 RNA helicase DUF87 PF01935.12 ETO11615.1 - 0.14 11.9 0.0 0.14 11.9 0.0 3.3 2 2 1 3 3 3 0 Domain of unknown function DUF87 Miro PF08477.8 ETO11615.1 - 0.4 11.1 7.7 0.17 12.3 0.2 3.3 2 2 0 2 2 2 0 Miro-like protein LNP1 PF15419.1 ETO11615.1 - 2.3 8.2 9.9 0.76 9.8 2.9 2.3 2 0 0 2 2 2 0 Leukemia NUP98 fusion partner 1 REV PF00424.13 ETO11616.1 - 0.01 15.6 2.5 0.22 11.4 0.6 2.7 1 1 0 2 2 2 0 REV protein (anti-repression trans-activator protein) CHMI PF02962.10 ETO11616.1 - 0.044 13.9 0.1 0.086 12.9 0.0 1.4 1 0 0 1 1 1 0 5-carboxymethyl-2-hydroxymuconate isomerase FUSC PF04632.7 ETO11616.1 - 0.14 10.5 2.3 0.18 10.2 1.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family SPX PF03105.14 ETO11616.1 - 0.25 11.0 24.9 0.066 12.9 5.2 2.2 1 1 1 2 2 2 0 SPX domain Spc7 PF08317.6 ETO11616.1 - 2.1 6.9 31.4 0.13 10.8 12.5 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein ERM PF00769.14 ETO11616.1 - 6.7 6.1 35.7 1.3 8.4 13.9 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF1664 PF07889.7 ETO11616.1 - 6.8 6.5 11.4 5.1 6.9 5.7 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Sec6 PF06046.8 ETO11617.1 - 2.8e-16 58.7 7.7 1.6e-11 43.0 0.1 2.6 2 1 0 2 2 2 2 Exocyst complex component Sec6 DUF445 PF04286.7 ETO11617.1 - 0.032 13.7 0.0 0.055 12.9 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) CDC37_N PF03234.9 ETO11617.1 - 0.064 13.5 0.1 0.15 12.3 0.1 1.7 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding G-gamma PF00631.17 ETO11618.1 - 1.4 8.6 8.8 0.11 12.2 0.4 2.7 3 0 0 3 3 3 0 GGL domain Kelch_1 PF01344.20 ETO11619.1 - 0.00069 19.1 0.5 0.0076 15.7 0.1 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO11619.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.7 1 0 0 1 1 1 0 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO11619.1 - 0.12 12.5 3.6 0.83 9.9 0.1 3.0 4 0 0 4 4 4 0 Kelch motif EnY2 PF10163.4 ETO11621.1 - 0.094 12.6 3.3 0.075 12.9 0.7 1.9 1 1 1 2 2 2 0 Transcription factor e(y)2 Tetraspannin PF00335.15 ETO11622.1 - 1.3e-24 86.7 16.9 1.8e-24 86.2 11.7 1.1 1 0 0 1 1 1 1 Tetraspanin family EVC2_like PF12297.3 ETO11622.1 - 0.16 10.6 1.6 0.42 9.1 0.1 1.9 1 1 1 2 2 2 0 Ellis van Creveld protein 2 like protein TACC PF05010.9 ETO11623.1 - 0.0043 16.8 0.2 0.0049 16.6 0.2 1.0 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) DUF365 PF04033.7 ETO11623.1 - 0.025 14.5 0.2 0.03 14.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF365) Bac_DnaA PF00308.13 ETO11623.1 - 0.074 12.6 0.3 0.11 12.1 0.2 1.3 1 1 0 1 1 1 0 Bacterial dnaA protein WASH-7_mid PF14744.1 ETO11624.1 - 0.014 14.2 2.0 0.014 14.2 1.4 1.1 1 0 0 1 1 1 0 WASH complex subunit 7 Peptidase_S46 PF10459.4 ETO11624.1 - 0.13 10.6 5.3 0.14 10.5 3.7 1.0 1 0 0 1 1 1 0 Peptidase S46 VTC PF09359.5 ETO11624.1 - 0.29 10.1 5.2 0.33 9.9 3.6 1.1 1 0 0 1 1 1 0 VTC domain zf-ZPR1 PF03367.8 ETO11624.1 - 0.49 9.5 3.4 1.3 8.1 2.4 1.8 1 1 0 1 1 1 0 ZPR1 zinc-finger domain PaaSYMP PF14738.1 ETO11624.1 - 1.7 8.3 10.6 3.3 7.4 7.4 1.5 1 1 0 1 1 1 0 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 KH_2 PF07650.12 ETO11624.1 - 2.7 7.6 7.0 1.5 8.4 2.9 2.1 2 1 1 3 3 3 0 KH domain UBN_AB PF14075.1 ETO11625.1 - 0.043 13.4 2.4 0.047 13.3 1.7 1.1 1 0 0 1 1 1 0 Ubinuclein conserved middle domain UCH PF00443.24 ETO11627.1 - 3.4e-18 65.7 9.9 1.1e-17 64.0 6.9 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 ETO11628.1 - 1.4e-32 112.8 0.1 1.4e-32 112.8 0.1 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO11628.1 - 1.5e-05 24.6 5.7 6.1e-05 22.6 4.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MBT PF02820.13 ETO11628.1 - 0.00012 21.8 0.1 0.0003 20.6 0.1 1.6 1 0 0 1 1 1 1 mbt repeat BSP_II PF05432.6 ETO11628.1 - 0.0004 19.7 4.0 0.00073 18.9 2.8 1.4 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) OPA3 PF07047.7 ETO11628.1 - 0.0082 15.9 0.5 0.024 14.4 0.3 1.7 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Tudor-knot PF11717.3 ETO11628.1 - 0.0087 15.7 5.2 0.24 11.1 0.8 3.3 3 0 0 3 3 3 1 RNA binding activity-knot of a chromodomain Nucleoplasmin PF03066.10 ETO11628.1 - 0.19 11.2 6.9 0.42 10.1 4.8 1.5 1 0 0 1 1 1 0 Nucleoplasmin Myc_N PF01056.13 ETO11628.1 - 0.57 9.2 7.5 1 8.4 5.2 1.3 1 0 0 1 1 1 0 Myc amino-terminal region DUF3682 PF12446.3 ETO11628.1 - 0.99 9.7 9.8 2.2 8.5 6.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) CENP-B_dimeris PF09026.5 ETO11628.1 - 2.3 8.5 10.8 1.3 9.2 5.8 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain WD40 PF00400.27 ETO11630.1 - 3.9e-16 58.2 0.3 5e-07 29.3 0.1 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat eIF2A PF08662.6 ETO11630.1 - 0.044 13.4 0.0 0.059 13.0 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A DUF4248 PF14053.1 ETO11630.1 - 0.13 11.8 0.1 0.95 9.0 0.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4248) WW PF00397.21 ETO11631.1 - 2.3e-19 68.8 16.4 5e-05 23.0 1.7 4.6 4 0 0 4 4 4 4 WW domain Macoilin PF09726.4 ETO11631.1 - 0.92 7.7 14.9 1.1 7.4 10.3 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4585 PF15232.1 ETO11631.1 - 1.3 8.9 4.2 38 4.2 0.0 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF4585) WD40 PF00400.27 ETO11632.1 - 2.5e-48 160.2 18.4 2.5e-12 46.1 0.1 6.5 6 1 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO11632.1 - 2.1e-06 26.1 1.5 0.077 11.1 0.2 3.9 1 1 3 4 4 4 3 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO11632.1 - 2.6e-05 24.4 3.7 4e-05 23.8 1.5 2.2 2 0 0 2 2 2 1 TRAF-type zinc finger TBPIP PF07106.8 ETO11632.1 - 0.0013 18.3 3.3 0.002 17.7 2.3 1.3 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1664 PF07889.7 ETO11632.1 - 0.007 16.1 1.3 0.017 14.9 0.7 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) Filament PF00038.16 ETO11632.1 - 0.0074 15.8 3.4 0.011 15.2 2.3 1.2 1 0 0 1 1 1 1 Intermediate filament protein DDE_Tnp_2 PF04693.7 ETO11632.1 - 0.0094 15.0 0.5 0.015 14.2 0.3 1.2 1 0 0 1 1 1 1 Archaeal putative transposase ISC1217 IncA PF04156.9 ETO11632.1 - 0.036 13.6 2.9 0.06 12.9 2.0 1.3 1 0 0 1 1 1 0 IncA protein Laminin_I PF06008.9 ETO11632.1 - 0.34 10.1 6.6 0.48 9.6 3.5 1.8 1 1 1 2 2 2 0 Laminin Domain I DUF3498 PF12004.3 ETO11632.1 - 0.44 9.6 2.4 0.66 9.0 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) DUF948 PF06103.6 ETO11632.1 - 1.6 8.6 3.2 5.8 6.8 0.2 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4315 PF14193.1 ETO11632.1 - 2.1 8.3 5.6 0.46 10.4 1.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) bZIP_1 PF00170.16 ETO11632.1 - 5.8 6.9 6.3 5.4 7.0 0.6 2.4 1 1 1 2 2 2 0 bZIP transcription factor TPR_12 PF13424.1 ETO11633.1 - 5.5e-17 61.4 0.1 7.8e-17 60.9 0.1 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO11633.1 - 1.4e-10 40.6 5.2 8.7e-09 34.9 1.1 1.7 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETO11633.1 - 9.7e-10 37.6 6.1 0.00022 20.6 0.9 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO11633.1 - 4.3e-09 35.6 1.7 0.00016 21.2 0.7 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO11633.1 - 1.9e-07 30.7 0.0 6.1e-06 25.9 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO11633.1 - 1.1e-06 27.9 7.4 0.006 16.2 0.3 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO11633.1 - 7.5e-06 25.7 1.1 0.06 13.5 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO11633.1 - 0.0011 18.5 0.5 0.44 10.4 0.1 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat SNAP PF14938.1 ETO11633.1 - 0.0065 15.6 0.4 0.015 14.4 0.2 1.5 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP EntA_Immun PF08951.5 ETO11633.1 - 0.034 14.2 0.2 0.072 13.2 0.1 1.6 1 0 0 1 1 1 0 Enterocin A Immunity Apc3 PF12895.2 ETO11633.1 - 0.05 13.7 1.0 0.13 12.3 0.3 1.8 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 CNF1 PF05785.7 ETO11633.1 - 0.057 12.3 0.2 0.078 11.8 0.1 1.2 1 1 0 1 1 1 0 Rho-activating domain of cytotoxic necrotizing factor TPR_21 PF09976.4 ETO11633.1 - 0.073 13.0 0.0 0.32 10.9 0.0 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat DUF2225 PF09986.4 ETO11633.1 - 0.079 12.4 1.6 0.87 9.0 1.1 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_6 PF13174.1 ETO11633.1 - 0.11 13.0 0.2 25 5.5 0.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.27 ETO11634.1 - 2.5e-55 182.4 9.8 2.9e-13 49.1 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO11634.1 - 6.6e-07 27.8 7.9 0.34 8.9 0.0 5.6 1 1 3 5 5 5 4 Nucleoporin Nup120/160 NYD-SP28_assoc PF14775.1 ETO11634.1 - 0.0001 21.9 0.4 42 3.9 0.0 5.9 6 0 0 6 6 6 0 Sperm tail C-terminal domain PD40 PF07676.7 ETO11634.1 - 0.00016 21.2 6.5 1.2 8.9 0.1 5.0 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 ETO11634.1 - 0.0027 16.3 1.7 0.45 9.0 0.0 3.6 3 1 1 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PQQ_2 PF13360.1 ETO11634.1 - 0.071 12.5 0.1 0.36 10.2 0.1 2.0 1 1 1 2 2 2 0 PQQ-like domain TFIIE_beta PF02186.10 ETO11634.1 - 0.09 12.7 0.2 12 5.9 0.0 2.8 2 0 0 2 2 2 0 TFIIE beta subunit core domain DUF3475 PF11961.3 ETO11634.1 - 0.1 12.4 0.0 17 5.3 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3475) Inhibitor_I24 PF10465.4 ETO11634.1 - 0.41 10.3 5.8 0.91 9.2 0.5 3.2 1 1 3 4 4 4 0 PinA peptidase inhibitor Mid2 PF04478.7 ETO11634.1 - 0.69 9.3 7.0 4.8 6.5 0.1 4.5 1 1 5 6 6 6 0 Mid2 like cell wall stress sensor WD40 PF00400.27 ETO11635.1 - 8e-87 282.3 21.8 4.1e-11 42.3 0.0 8.5 8 0 0 8 8 8 8 WD domain, G-beta repeat NACHT PF05729.7 ETO11635.1 - 3.2e-10 39.9 0.0 6.4e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DUF1258 PF06869.7 ETO11635.1 - 4.7e-06 25.8 5.2 0.15 11.1 0.0 4.8 4 1 1 5 5 5 2 Protein of unknown function (DUF1258) Pentapeptide_4 PF13599.1 ETO11635.1 - 3.9e-05 23.3 0.4 0.00011 21.9 0.3 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA_18 PF13238.1 ETO11635.1 - 0.00014 22.1 0.0 0.00014 22.1 0.0 3.7 2 2 2 4 4 4 1 AAA domain AAA_22 PF13401.1 ETO11635.1 - 0.00015 21.9 0.0 0.00072 19.6 0.0 2.2 1 0 0 1 1 1 1 AAA domain Pentapeptide PF00805.17 ETO11635.1 - 0.00029 20.0 3.7 0.00066 18.8 2.3 1.7 1 1 0 1 1 1 1 Pentapeptide repeats (8 copies) UPF0079 PF02367.12 ETO11635.1 - 0.00029 20.4 0.1 0.001 18.6 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Pentapeptide_3 PF13576.1 ETO11635.1 - 0.0013 18.5 0.3 0.0037 17.1 0.2 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA_17 PF13207.1 ETO11635.1 - 0.0028 18.4 0.2 0.022 15.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 ETO11635.1 - 0.023 15.0 0.2 0.25 11.6 0.0 2.8 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.1 ETO11635.1 - 0.11 12.3 0.0 0.36 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain BSD PF03909.12 ETO11635.1 - 0.14 11.9 4.5 7.9 6.2 0.4 3.3 3 0 0 3 3 2 0 BSD domain AAA_16 PF13191.1 ETO11635.1 - 0.23 11.4 0.4 1.8 8.5 0.1 2.5 2 1 0 2 2 2 0 AAA ATPase domain Nop14 PF04147.7 ETO11636.1 - 0.18 9.6 34.5 0.22 9.4 23.9 1.1 1 0 0 1 1 1 0 Nop14-like family adh_short PF00106.20 ETO11637.1 - 3.8e-07 30.1 0.0 0.0015 18.5 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase DUF4131 PF13567.1 ETO11637.1 - 0.047 13.1 4.7 0.7 9.2 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) PNRC PF15365.1 ETO11637.1 - 0.068 13.1 6.3 0.22 11.5 4.3 1.9 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator Glyco_tran_WecB PF03808.8 ETO11637.1 - 0.088 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family ODV-E18 PF10717.4 ETO11638.1 - 0.045 13.1 1.0 0.1 12.0 0.7 1.7 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 APC_CDC26 PF10471.4 ETO11639.1 - 0.46 11.2 6.6 0.78 10.5 4.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Kinesin PF00225.18 ETO11640.1 - 5.3e-19 68.1 0.1 6.5e-19 67.8 0.1 1.1 1 0 0 1 1 1 1 Kinesin motor domain AAA_22 PF13401.1 ETO11640.1 - 0.023 14.8 0.4 0.046 13.8 0.3 1.8 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 ETO11640.1 - 0.057 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 ETO11640.1 - 0.094 12.6 0.0 0.22 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain BCDHK_Adom3 PF10436.4 ETO11642.1 - 2.5e-25 88.8 0.5 2.7e-17 62.7 0.1 2.5 2 0 0 2 2 2 2 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 ETO11642.1 - 7.4e-11 41.7 0.0 5e-10 39.0 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 ETO11642.1 - 0.038 13.6 0.0 0.085 12.5 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase B56 PF01603.15 ETO11643.1 - 1.8e-86 290.3 10.7 1.1e-85 287.6 7.4 1.9 1 1 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF2762 PF10960.3 ETO11643.1 - 0.021 14.4 0.2 0.088 12.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2762) WD40 PF00400.27 ETO11645.1 - 1.2e-08 34.5 0.5 1e-06 28.3 0.1 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO11645.1 - 0.0043 15.2 0.0 0.0066 14.6 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Lipase_GDSL_2 PF13472.1 ETO11646.1 - 0.00022 21.3 0.0 0.00022 21.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family WD40 PF00400.27 ETO11649.1 - 1e-33 113.9 15.9 4.4e-11 42.2 0.1 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO11649.1 - 2e-09 36.1 0.1 0.0028 15.8 0.0 3.0 3 0 0 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO11649.1 - 0.011 14.5 2.5 2.1 6.9 0.7 3.0 1 1 1 3 3 3 0 Nup133 N terminal like Cnd1 PF12717.2 ETO11650.1 - 1.7e-05 24.7 12.0 0.00084 19.2 5.6 3.1 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 ETO11650.1 - 0.0033 17.3 0.0 82 3.6 0.0 4.8 4 0 0 4 4 4 0 HEAT repeat DUF3349 PF11829.3 ETO11650.1 - 0.021 15.2 0.1 19 5.7 0.0 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3349) HEAT_EZ PF13513.1 ETO11650.1 - 0.18 12.3 0.0 2 8.9 0.0 2.7 4 0 0 4 4 4 0 HEAT-like repeat Colicin PF01024.14 ETO11650.1 - 0.18 11.3 3.3 1.8 8.1 0.2 3.3 1 1 3 4 4 4 0 Colicin pore forming domain DUF3440 PF11922.3 ETO11650.1 - 9 5.8 8.7 2.9 7.4 3.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3440) WD40 PF00400.27 ETO11652.1 - 5.8e-39 130.6 21.6 4.8e-08 32.5 0.0 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO11652.1 - 6e-06 24.6 0.3 0.24 9.5 0.1 3.2 2 1 1 3 3 3 3 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO11652.1 - 0.0052 16.1 2.6 0.22 10.8 0.3 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4221) eIF2A PF08662.6 ETO11652.1 - 0.01 15.5 0.2 0.22 11.2 0.0 2.4 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A RPEL PF02755.10 ETO11653.1 - 0.0076 15.5 10.2 0.025 13.8 0.2 4.5 6 0 0 6 6 6 2 RPEL repeat SseB_C PF14581.1 ETO11653.1 - 0.016 15.0 1.6 0.39 10.5 0.0 3.1 3 0 0 3 3 3 0 SseB protein C-terminal domain Pkinase PF00069.20 ETO11654.1 - 8e-06 25.1 0.0 1.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO11654.1 - 0.00066 18.8 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EphA2_TM PF14575.1 ETO11654.1 - 0.11 12.9 0.3 1.7 9.1 0.0 2.8 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Pkinase_Tyr PF07714.12 ETO11655.1 - 3.7e-44 150.7 0.0 6e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 ETO11655.1 - 1.3e-29 103.1 0.0 2.4e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 ETO11656.1 - 3.2e-22 78.9 0.0 1.6e-21 76.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO11656.1 - 2.1e-06 27.0 0.0 0.00024 20.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase His_Phos_1 PF00300.17 ETO11657.1 - 1.3e-06 28.5 11.8 0.0072 16.4 0.0 3.4 2 1 1 3 3 3 3 Histidine phosphatase superfamily (branch 1) HNH_4 PF13395.1 ETO11658.1 - 0.0081 15.7 0.2 0.024 14.2 0.0 1.9 2 0 0 2 2 2 1 HNH endonuclease Act-Frag_cataly PF09192.5 ETO11658.1 - 0.012 14.5 0.4 0.015 14.3 0.3 1.1 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic Pkinase PF00069.20 ETO11659.1 - 0.00085 18.5 1.4 0.76 8.8 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain dTMP_synthase PF02593.9 ETO11663.1 - 0.031 13.6 0.5 0.038 13.3 0.0 1.3 2 0 0 2 2 2 0 Thymidylate synthase EFG_IV PF03764.13 ETO11663.1 - 0.077 12.5 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Elongation factor G, domain IV EMP24_GP25L PF01105.19 ETO11663.1 - 0.11 12.1 1.2 0.14 11.8 0.8 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD MAS20 PF02064.10 ETO11663.1 - 0.2 11.5 0.9 0.27 11.1 0.6 1.2 1 0 0 1 1 1 0 MAS20 protein import receptor FKBP_N PF01346.13 ETO11663.1 - 3.4 7.7 8.0 2.1 8.4 3.0 2.0 1 1 1 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF4163 PF13739.1 ETO11663.1 - 5.1 7.9 6.8 29 5.5 4.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4163) Kelch_1 PF01344.20 ETO11664.1 - 0.00034 20.0 0.1 0.00081 18.8 0.0 1.6 1 0 0 1 1 1 1 Kelch motif Kelch_2 PF07646.10 ETO11664.1 - 0.0027 17.4 0.1 0.0064 16.2 0.0 1.7 1 0 0 1 1 1 1 Kelch motif Sigma70_ner PF04546.8 ETO11664.1 - 0.0062 16.1 4.8 0.0084 15.7 3.3 1.1 1 0 0 1 1 1 1 Sigma-70, non-essential region Vfa1 PF08432.5 ETO11664.1 - 0.0064 16.5 2.4 0.0091 16.0 1.7 1.2 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 FAM176 PF14851.1 ETO11664.1 - 0.0088 15.7 1.7 0.013 15.2 1.2 1.3 1 0 0 1 1 1 1 FAM176 family Kelch_6 PF13964.1 ETO11664.1 - 0.015 15.4 0.1 0.035 14.2 0.0 1.6 1 0 0 1 1 1 0 Kelch motif Kelch_5 PF13854.1 ETO11664.1 - 0.019 14.9 0.5 0.042 13.8 0.1 1.7 2 0 0 2 2 2 0 Kelch motif GBP_C PF02841.9 ETO11664.1 - 0.03 13.5 2.9 0.037 13.2 2.0 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Nucleoplasmin PF03066.10 ETO11664.1 - 0.03 13.8 13.1 0.05 13.1 9.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin Kelch_4 PF13418.1 ETO11664.1 - 0.04 13.6 0.0 0.13 12.0 0.0 1.9 1 1 1 2 2 2 0 Galactose oxidase, central domain S-antigen PF05756.6 ETO11664.1 - 0.042 13.8 5.4 0.08 12.9 3.7 1.4 1 0 0 1 1 1 0 S-antigen protein CENP-B_dimeris PF09026.5 ETO11664.1 - 0.046 13.9 5.8 0.085 13.0 4.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sporozoite_P67 PF05642.6 ETO11664.1 - 0.048 11.5 2.1 0.05 11.4 1.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ECIST_Cterm PF14784.1 ETO11664.1 - 0.052 13.5 1.3 0.083 12.8 0.9 1.3 1 0 0 1 1 1 0 C-terminal domain of the ECSIT protein Nop14 PF04147.7 ETO11664.1 - 0.063 11.2 7.7 0.076 10.9 5.3 1.1 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.13 ETO11664.1 - 0.078 12.1 2.3 0.091 11.9 1.6 1.1 1 0 0 1 1 1 0 Myc amino-terminal region CDC45 PF02724.9 ETO11664.1 - 0.082 10.9 5.9 0.091 10.7 4.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RNase_H2_suC PF08615.6 ETO11664.1 - 0.083 12.7 0.4 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) TRAP_alpha PF03896.11 ETO11664.1 - 0.1 11.5 3.5 0.14 11.1 2.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CobT PF06213.7 ETO11664.1 - 0.13 11.3 7.1 0.17 11.0 4.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.7 ETO11664.1 - 0.3 10.3 5.7 0.45 9.7 3.9 1.2 1 0 0 1 1 1 0 NOA36 protein Pox_Ag35 PF03286.9 ETO11664.1 - 1.7 8.1 8.7 2.4 7.6 6.0 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PBP1_TM PF14812.1 ETO11664.1 - 1.9 8.8 7.6 3.8 7.8 5.3 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.4 ETO11664.1 - 6 5.4 13.2 7.9 5.0 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SspB PF04386.8 ETO11664.1 - 6.9 6.2 7.0 9.8 5.7 4.9 1.2 1 0 0 1 1 1 0 Stringent starvation protein B F-box PF00646.28 ETO11665.1 - 0.00058 19.4 0.0 0.00095 18.7 0.0 1.3 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 ETO11665.1 - 0.00096 18.8 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 F-box-like 2OG-FeII_Oxy_3 PF13640.1 ETO11666.1 - 2.5e-05 24.7 0.0 7.6e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Peptidase_C14 PF00656.17 ETO11667.1 - 3e-11 43.4 0.6 4.1e-11 43.0 0.4 1.2 1 0 0 1 1 1 1 Caspase domain UL11 PF11094.3 ETO11667.1 - 0.11 12.3 0.1 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Membrane-associated tegument protein Peptidase_C14 PF00656.17 ETO11668.1 - 9.5e-05 22.1 0.1 0.00016 21.4 0.1 1.4 1 1 0 1 1 1 1 Caspase domain HTH_Tnp_1_2 PF13022.1 ETO11668.1 - 0.073 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase WD40 PF00400.27 ETO11669.1 - 6.4e-41 136.7 16.1 1.2e-11 44.0 1.0 5.8 5 1 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO11669.1 - 1.2e-06 26.9 0.2 0.035 12.2 0.0 3.4 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO11669.1 - 0.003 16.3 5.1 0.33 9.6 0.9 3.3 1 1 2 3 3 3 3 Nup133 N terminal like RBD PF02196.10 ETO11671.1 - 0.0004 20.0 0.0 0.0011 18.7 0.0 1.7 2 0 0 2 2 2 1 Raf-like Ras-binding domain RA PF00788.18 ETO11671.1 - 0.0074 16.7 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Bul1_C PF04426.7 ETO11671.1 - 0.022 13.9 0.2 0.022 13.9 0.2 1.7 2 0 0 2 2 2 0 Bul1 C terminus AP3B1_C PF14796.1 ETO11671.1 - 0.052 13.2 0.1 0.094 12.4 0.0 1.5 1 1 0 1 1 1 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal Rad60-SLD PF11976.3 ETO11671.1 - 0.17 11.5 1.9 0.22 11.2 0.2 1.9 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Phage_min_tail PF05939.8 ETO11672.1 - 0.05 13.5 0.2 0.082 12.8 0.1 1.4 1 0 0 1 1 1 0 Phage minor tail protein PHTB1_C PF14728.1 ETO11672.1 - 0.09 11.5 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 PTHB1 C-terminus Myosin_tail_1 PF01576.14 ETO11673.1 - 0.00043 18.1 7.6 0.00065 17.5 5.3 1.2 1 0 0 1 1 1 1 Myosin tail Atg14 PF10186.4 ETO11673.1 - 0.00081 18.4 1.1 0.001 18.0 0.8 1.4 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Fmp27_WPPW PF10359.4 ETO11673.1 - 0.0015 17.0 5.8 0.0026 16.2 4.0 1.3 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Lipoprotein_7 PF01540.11 ETO11673.1 - 0.0015 17.6 4.3 0.0022 17.1 2.9 1.1 1 0 0 1 1 1 1 Adhesin lipoprotein CENP-F_leu_zip PF10473.4 ETO11673.1 - 0.0018 18.1 6.4 0.0018 18.1 4.5 1.8 2 0 0 2 2 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin PF00261.15 ETO11673.1 - 0.0027 16.8 7.3 0.0027 16.8 5.1 1.7 2 0 0 2 2 2 1 Tropomyosin GAS PF13851.1 ETO11673.1 - 0.0042 16.3 11.8 0.0042 16.3 8.2 2.0 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding ALIX_LYPXL_bnd PF13949.1 ETO11673.1 - 0.0057 15.6 9.3 0.01 14.8 6.5 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF3450 PF11932.3 ETO11673.1 - 0.01 15.0 10.0 0.018 14.3 6.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) OmpH PF03938.9 ETO11673.1 - 0.015 15.2 4.9 0.027 14.4 3.4 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) bZIP_1 PF00170.16 ETO11673.1 - 0.015 15.2 2.7 0.015 15.2 1.9 2.7 1 1 1 2 2 2 0 bZIP transcription factor DUF4131 PF13567.1 ETO11673.1 - 0.016 14.6 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF4337 PF14235.1 ETO11673.1 - 0.021 14.6 4.3 0.038 13.8 2.3 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF4337) UPF0118 PF01594.11 ETO11673.1 - 0.026 13.5 5.9 0.097 11.6 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF20 DUF342 PF03961.8 ETO11673.1 - 0.027 12.9 4.1 0.039 12.3 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF812 PF05667.6 ETO11673.1 - 0.027 12.9 7.5 0.064 11.7 5.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF812) SURF4 PF02077.10 ETO11673.1 - 0.031 13.6 2.9 1.1 8.5 1.6 2.3 2 0 0 2 2 2 0 SURF4 family PilJ PF13675.1 ETO11673.1 - 0.034 14.4 4.1 0.28 11.5 0.3 2.4 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4407 PF14362.1 ETO11673.1 - 0.099 11.5 2.9 0.18 10.7 2.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Reo_sigmaC PF04582.7 ETO11673.1 - 0.11 11.6 0.6 0.15 11.1 0.4 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Phlebovirus_NSM PF07246.6 ETO11673.1 - 0.11 11.5 4.9 0.23 10.5 3.4 1.5 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M HALZ PF02183.13 ETO11673.1 - 0.11 12.1 4.6 0.41 10.4 1.6 2.8 2 1 0 2 2 2 0 Homeobox associated leucine zipper HlyD PF00529.15 ETO11673.1 - 0.13 11.5 3.4 0.19 10.9 2.4 1.3 1 0 0 1 1 1 0 HlyD family secretion protein DUF3278 PF11683.3 ETO11673.1 - 0.13 12.2 2.9 0.26 11.2 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3278) WXG100 PF06013.7 ETO11673.1 - 0.14 12.1 4.0 4.2 7.4 2.7 3.0 1 1 0 1 1 1 0 Proteins of 100 residues with WXG STAT_alpha PF01017.15 ETO11673.1 - 0.14 11.8 10.6 0.041 13.5 3.8 2.2 1 1 1 2 2 2 0 STAT protein, all-alpha domain FlaC_arch PF05377.6 ETO11673.1 - 0.16 11.8 10.1 0.27 11.1 0.4 3.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Ax_dynein_light PF10211.4 ETO11673.1 - 0.2 11.4 10.6 0.059 13.2 4.2 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain AMP-binding_C_2 PF14535.1 ETO11673.1 - 0.21 11.6 1.5 0.42 10.6 1.0 1.4 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain T2SF PF00482.18 ETO11673.1 - 0.22 11.4 1.0 0.46 10.4 0.1 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F FUN14 PF04930.10 ETO11673.1 - 0.23 11.7 6.5 1.9 8.8 4.5 2.4 1 1 0 1 1 1 0 FUN14 family Phage_GP20 PF06810.6 ETO11673.1 - 0.24 10.8 16.9 0.033 13.6 8.7 1.8 2 0 0 2 2 1 0 Phage minor structural protein GP20 Spc7 PF08317.6 ETO11673.1 - 0.26 9.9 14.3 0.48 9.0 2.0 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DASH_Dad2 PF08654.5 ETO11673.1 - 0.27 11.2 13.4 0.63 10.0 2.8 3.1 3 1 1 4 4 2 0 DASH complex subunit Dad2 Syntaxin-6_N PF09177.6 ETO11673.1 - 0.28 11.5 7.4 0.91 9.9 3.2 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal V_ATPase_I PF01496.14 ETO11673.1 - 0.33 8.7 12.7 0.072 10.9 6.4 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Laminin_II PF06009.7 ETO11673.1 - 0.34 10.6 13.8 0.05 13.3 6.4 1.9 2 1 0 2 2 1 0 Laminin Domain II MCPsignal PF00015.16 ETO11673.1 - 0.38 10.2 5.6 0.24 10.9 1.4 2.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DivIC PF04977.10 ETO11673.1 - 0.44 10.0 16.1 0.31 10.5 7.0 3.1 2 1 0 2 2 1 0 Septum formation initiator COMP PF11598.3 ETO11673.1 - 0.47 10.5 3.8 8.8 6.4 0.3 3.1 2 1 1 3 3 3 0 Cartilage oligomeric matrix protein DUF3347 PF11827.3 ETO11673.1 - 0.56 10.1 7.7 0.11 12.5 2.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) H-kinase_dim PF02895.9 ETO11673.1 - 0.74 10.2 4.5 33 4.8 2.5 2.9 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain DUF3007 PF11460.3 ETO11673.1 - 0.8 9.8 8.3 0.41 10.7 2.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3007) DUF3373 PF11853.3 ETO11673.1 - 0.87 8.0 5.2 0.35 9.3 1.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) TBPIP PF07106.8 ETO11673.1 - 0.95 8.9 15.3 0.19 11.2 7.7 1.9 2 1 0 2 2 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mnd1 PF03962.10 ETO11673.1 - 1 8.9 12.7 0.13 11.9 5.5 1.8 2 0 0 2 2 2 0 Mnd1 family Fib_alpha PF08702.5 ETO11673.1 - 1.1 9.4 10.5 10 6.2 7.3 2.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family APG6 PF04111.7 ETO11673.1 - 1.4 7.8 15.0 0.03 13.3 5.5 1.7 3 0 0 3 3 1 0 Autophagy protein Apg6 Prefoldin PF02996.12 ETO11673.1 - 2.2 7.9 10.7 1.5 8.5 4.3 2.4 1 1 1 2 2 2 0 Prefoldin subunit CASP_C PF08172.7 ETO11673.1 - 2.3 7.1 9.0 7.3 5.5 5.6 2.2 1 1 0 1 1 1 0 CASP C terminal DUF724 PF05266.9 ETO11673.1 - 2.5 7.6 15.4 0.067 12.8 5.6 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF724) LOH1CR12 PF10158.4 ETO11673.1 - 2.6 7.8 7.1 11 5.7 4.4 1.9 1 1 0 1 1 1 0 Tumour suppressor protein Syntaxin PF00804.20 ETO11673.1 - 3 8.0 13.6 0.53 10.4 6.4 2.0 2 0 0 2 2 1 0 Syntaxin NPV_P10 PF05531.7 ETO11673.1 - 3.3 8.0 10.3 3.2 8.0 4.2 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2570 PF10828.3 ETO11673.1 - 4.4 6.9 12.1 0.1 12.1 3.5 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF2570) IncA PF04156.9 ETO11673.1 - 5.2 6.6 17.8 23 4.4 12.4 2.1 1 1 0 1 1 1 0 IncA protein DUF4446 PF14584.1 ETO11673.1 - 6.1 6.6 9.1 1.7 8.4 2.9 2.6 2 1 1 3 3 2 0 Protein of unknown function (DUF4446) DUF1664 PF07889.7 ETO11673.1 - 6.2 6.6 12.5 1.2 8.8 4.1 2.5 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) DUF2852 PF11014.3 ETO11673.1 - 6.8 6.6 10.5 10 6.1 5.4 2.6 2 1 0 2 2 1 0 Protein of unknown function (DUF2852) Tup_N PF08581.5 ETO11673.1 - 7.3 6.8 12.9 5 7.3 0.4 2.6 1 1 1 2 2 2 0 Tup N-terminal BLOC1_2 PF10046.4 ETO11673.1 - 7.8 6.7 16.0 0.38 10.9 5.9 2.4 2 1 1 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prefoldin_2 PF01920.15 ETO11673.1 - 7.8 6.3 17.1 5.5 6.8 4.1 2.7 2 1 1 3 3 2 0 Prefoldin subunit DivIVA PF05103.8 ETO11673.1 - 9.7 6.2 19.8 5.5 7.0 6.1 2.8 2 1 1 3 3 2 0 DivIVA protein DUF2207 PF09972.4 ETO11674.1 - 0.46 8.9 2.1 0.53 8.7 1.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Use1 PF09753.4 ETO11674.1 - 2 7.7 3.6 3.1 7.1 2.5 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 VirB3 PF05101.8 ETO11674.1 - 4.2 7.4 8.3 6.7 6.7 5.8 1.3 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein WD40 PF00400.27 ETO11678.1 - 5.1e-73 238.5 18.8 1.1e-10 40.9 0.5 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO11678.1 - 1.5e-06 26.6 11.5 0.18 9.8 0.2 4.4 1 1 3 4 4 4 4 Nucleoporin Nup120/160 DUF1258 PF06869.7 ETO11678.1 - 0.0014 17.8 8.3 0.11 11.5 0.1 4.5 3 1 2 5 5 5 1 Protein of unknown function (DUF1258) PQQ_2 PF13360.1 ETO11678.1 - 0.01 15.3 0.0 0.036 13.5 0.0 1.9 1 1 0 1 1 1 0 PQQ-like domain SMN PF06003.7 ETO11678.1 - 0.019 14.0 1.7 0.031 13.3 1.2 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DUF4306 PF14154.1 ETO11678.1 - 0.091 12.7 2.0 1.5 8.8 0.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4306) PD40 PF07676.7 ETO11678.1 - 0.4 10.4 4.9 26 4.5 0.0 4.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 ETO11679.1 - 1.8e-16 59.3 0.5 4.2e-09 35.9 0.0 2.9 4 0 0 4 4 4 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO11679.1 - 0.00085 17.5 0.1 0.38 8.8 0.0 2.0 1 1 0 2 2 2 2 Nucleoporin Nup120/160 HIN PF02760.10 ETO11679.1 - 0.037 13.4 0.6 0.42 9.9 0.3 2.1 1 1 1 2 2 2 0 HIN-200/IF120x domain BBS2_Mid PF14783.1 ETO11679.1 - 0.05 13.3 0.2 0.072 12.8 0.1 1.3 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region DUF2480 PF10652.4 ETO11679.1 - 0.093 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2480) PABP PF00658.13 ETO11680.1 - 4.4e-24 83.9 2.0 8.6e-24 82.9 1.4 1.5 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_1 PF00076.17 ETO11680.1 - 1.7e-22 78.7 0.0 2.7e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO11680.1 - 6.2e-17 61.3 0.0 1e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO11680.1 - 1.3e-11 44.1 0.0 2.8e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TMF_TATA_bd PF12325.3 ETO11681.1 - 0.0017 18.0 2.9 0.0025 17.5 2.0 1.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF972 PF06156.8 ETO11681.1 - 0.019 15.3 3.5 0.028 14.7 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.10 ETO11681.1 - 0.042 13.3 1.9 0.06 12.8 0.5 1.8 1 1 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.16 ETO11681.1 - 0.06 13.3 0.8 0.14 12.1 0.5 1.6 1 0 0 1 1 1 0 bZIP transcription factor Herpes_BLRF2 PF05812.7 ETO11681.1 - 0.12 12.2 1.6 0.21 11.3 1.1 1.4 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Geminin PF07412.7 ETO11681.1 - 1.1 8.8 7.5 1.6 8.3 5.2 1.1 1 0 0 1 1 1 0 Geminin DUF4492 PF14899.1 ETO11682.1 - 0.023 14.1 2.1 0.023 14.1 1.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4492) Methyltransf_28 PF02636.12 ETO11684.1 - 8.4e-16 58.1 0.0 9.3e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Pec_lyase_C PF00544.14 ETO11685.1 - 0.025 14.0 0.2 0.037 13.4 0.0 1.4 2 0 0 2 2 2 0 Pectate lyase Baculo_LEF-11 PF06385.7 ETO11685.1 - 0.071 13.2 1.8 0.07 13.2 0.4 1.6 1 1 1 2 2 2 0 Baculovirus LEF-11 protein Exo_endo_phos_2 PF14529.1 ETO11686.1 - 7.7e-06 25.5 0.1 1.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF2430 PF10353.4 ETO11687.1 - 0.014 15.5 0.2 0.033 14.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2430) RestrictionMunI PF11407.3 ETO11688.1 - 0.13 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Type II restriction enzyme MunI DYW_deaminase PF14432.1 ETO11689.1 - 0.065 13.2 0.6 0.16 11.9 0.4 1.7 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases Sedlin_N PF04628.8 ETO11689.1 - 0.14 12.0 6.1 1.3 8.9 0.7 2.3 1 1 1 2 2 2 0 Sedlin, N-terminal conserved region HSF_DNA-bind PF00447.12 ETO11691.1 - 0.008 16.3 4.7 0.067 13.3 3.2 2.2 1 1 0 1 1 1 1 HSF-type DNA-binding Transp_cyt_pur PF02133.10 ETO11691.1 - 0.052 12.0 0.4 0.11 10.9 0.1 1.5 1 1 1 2 2 2 0 Permease for cytosine/purines, uracil, thiamine, allantoin Myosin_head PF00063.16 ETO11692.1 - 8.4e-117 390.9 8.8 8.4e-117 390.9 6.1 2.5 2 1 0 2 2 2 1 Myosin head (motor domain) Claudin_2 PF13903.1 ETO11693.1 - 1.3 8.6 6.6 1.7e+02 1.8 4.6 2.5 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction WD40 PF00400.27 ETO11694.1 - 0.022 14.6 0.0 0.13 12.2 0.0 2.2 2 1 0 2 2 2 0 WD domain, G-beta repeat WD40 PF00400.27 ETO11695.1 - 6.6e-152 488.6 41.1 7.4e-12 44.6 0.1 15.0 15 0 0 15 15 15 14 WD domain, G-beta repeat NACHT PF05729.7 ETO11695.1 - 2.1e-11 43.7 0.0 4.5e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PQQ_2 PF13360.1 ETO11695.1 - 1.3e-07 31.3 2.2 3.5e-05 23.3 0.2 4.1 1 1 3 4 4 4 1 PQQ-like domain Pentapeptide PF00805.17 ETO11695.1 - 4.6e-06 25.7 4.7 1.4e-05 24.2 3.3 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO11695.1 - 5.1e-06 26.1 0.5 1.4e-05 24.8 0.3 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA_18 PF13238.1 ETO11695.1 - 1e-05 25.8 3.3 0.00014 22.1 0.0 3.3 2 0 0 2 2 2 1 AAA domain DUF1652 PF07865.6 ETO11695.1 - 0.00026 20.5 1.0 33 4.1 0.0 7.4 10 1 1 11 11 11 0 Protein of unknown function (DUF1652) AAA_22 PF13401.1 ETO11695.1 - 0.00039 20.5 0.0 0.00095 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO11695.1 - 0.0011 19.7 0.3 0.0059 17.4 0.0 2.4 2 0 0 2 2 1 1 AAA domain Pentapeptide_3 PF13576.1 ETO11695.1 - 0.002 17.9 0.2 0.0064 16.3 0.1 1.9 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA_33 PF13671.1 ETO11695.1 - 0.11 12.4 0.1 4.3 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain PD40 PF07676.7 ETO11695.1 - 2.9 7.6 19.0 13 5.5 0.1 6.5 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 ETO11696.1 - 1.3e-24 85.1 0.8 7.1e-13 47.8 0.1 3.1 2 0 0 2 2 2 2 WD domain, G-beta repeat Kelch_4 PF13418.1 ETO11696.1 - 0.0092 15.7 0.8 0.044 13.5 0.1 2.4 3 0 0 3 3 3 1 Galactose oxidase, central domain SMI1_KNR4 PF09346.5 ETO11696.1 - 0.02 14.9 1.7 0.037 14.0 0.2 2.1 2 0 0 2 2 2 0 SMI1 / KNR4 family (SUKH-1) Kelch_6 PF13964.1 ETO11696.1 - 0.026 14.7 1.0 0.48 10.6 0.2 2.9 2 0 0 2 2 2 0 Kelch motif Kelch_1 PF01344.20 ETO11696.1 - 0.051 13.1 0.9 0.34 10.4 0.2 2.5 2 0 0 2 2 2 0 Kelch motif DUF2414 PF10309.4 ETO11696.1 - 0.073 12.7 0.9 0.21 11.3 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2414) Kelch_3 PF13415.1 ETO11696.1 - 0.077 13.1 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 Galactose oxidase, central domain Pox_Ag35 PF03286.9 ETO11698.1 - 0.072 12.6 18.6 0.088 12.3 12.9 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein MCM2_N PF12619.3 ETO11698.1 - 0.39 10.7 14.4 0.59 10.0 10.0 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 DDRGK PF09756.4 ETO11698.1 - 0.84 9.0 28.1 0.96 8.8 19.5 1.2 1 0 0 1 1 1 0 DDRGK domain Vfa1 PF08432.5 ETO11698.1 - 2.2 8.2 21.9 3 7.8 15.2 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1510 PF07423.6 ETO11698.1 - 3.2 7.0 19.8 4 6.7 13.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Cellulose_synt PF03552.9 ETO11698.1 - 3.6 5.7 8.9 3.7 5.7 6.2 1.1 1 0 0 1 1 1 0 Cellulose synthase MIP-T3 PF10243.4 ETO11698.1 - 3.6 5.9 29.6 4.1 5.7 20.5 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Peptidase_S64 PF08192.6 ETO11698.1 - 4 5.6 9.7 4.5 5.4 6.7 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF2413 PF10310.4 ETO11698.1 - 4.6 5.9 17.1 5.4 5.7 11.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF4557 PF15101.1 ETO11698.1 - 7.8 6.2 10.3 9.6 5.9 7.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Neur_chan_memb PF02932.11 ETO11698.1 - 8.1 6.2 10.4 8.3 6.2 7.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2058 PF09831.4 ETO11698.1 - 8.9 6.1 20.9 11 5.8 14.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) NACHT PF05729.7 ETO11699.1 - 1e-07 31.7 0.0 3.8e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 ETO11699.1 - 0.025 14.5 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF3474 PF11960.3 ETO11700.1 - 0.076 13.0 0.6 0.17 11.9 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3474) WD40 PF00400.27 ETO11701.1 - 2e-42 141.5 11.5 3.3e-11 42.6 0.2 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO11701.1 - 1.1e-13 50.1 1.4 0.00018 19.7 0.0 4.0 1 1 3 4 4 4 4 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO11701.1 - 0.038 13.9 0.1 1.6 8.6 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3601) POT1 PF02765.12 ETO11701.1 - 0.55 10.1 4.1 1 9.2 2.8 1.6 1 1 0 1 1 1 0 Telomeric single stranded DNA binding POT1/CDC13 WD40 PF00400.27 ETO11703.1 - 3.8e-44 147.0 16.2 6.6e-11 41.6 0.1 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO11703.1 - 1.3e-05 23.5 4.3 0.19 9.8 0.2 4.1 2 1 1 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO11703.1 - 0.0021 16.8 7.8 0.6 8.7 4.7 3.7 1 1 1 2 2 2 1 Nup133 N terminal like HAD PF12710.2 ETO11703.1 - 0.19 11.8 0.9 4 7.5 0.0 2.7 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase TPR_12 PF13424.1 ETO11705.1 - 1.1e-14 54.1 0.0 2.9e-14 52.7 0.0 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO11705.1 - 2.6e-09 36.2 2.7 8.6e-09 34.6 1.9 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO11705.1 - 1.8e-08 33.5 0.1 5e-08 32.1 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO11705.1 - 2.6e-08 33.0 3.6 1e-07 31.2 2.5 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO11705.1 - 1.8e-07 30.6 1.0 3.9e-07 29.6 0.0 2.1 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 ETO11705.1 - 2.6e-07 30.0 2.1 7.7e-07 28.5 1.5 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETO11705.1 - 1.5e-06 27.9 0.0 3e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Peptidase_C14 PF00656.17 ETO11705.1 - 2.1e-05 24.3 2.0 0.0044 16.7 0.1 2.4 1 1 1 2 2 2 2 Caspase domain TPR_6 PF13174.1 ETO11705.1 - 0.0029 17.9 0.5 0.0075 16.6 0.3 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat Pox_TAA1 PF03295.9 ETO11705.1 - 0.0046 16.5 0.2 0.42 10.2 0.1 2.9 2 0 0 2 2 2 1 Poxvirus trans-activator protein A1 C-terminal TPR_14 PF13428.1 ETO11705.1 - 0.017 15.6 0.0 0.043 14.4 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETO11705.1 - 0.021 15.4 0.0 0.042 14.5 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.1 ETO11705.1 - 0.023 14.8 0.0 0.12 12.5 0.0 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Med22 PF06179.7 ETO11705.1 - 0.063 13.2 3.8 0.11 12.5 0.8 2.8 1 1 1 2 2 2 0 Surfeit locus protein 5 subunit 22 of Mediator complex MIT PF04212.13 ETO11705.1 - 0.075 12.9 0.9 0.19 11.6 0.6 1.7 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.1 ETO11705.1 - 0.11 12.8 0.1 0.29 11.5 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Cys_knot PF00007.17 ETO11706.1 - 0.0012 18.9 5.3 0.0012 18.9 3.7 2.3 1 1 2 3 3 3 1 Cystine-knot domain Neugrin PF06413.6 ETO11706.1 - 0.0047 16.7 1.2 0.0057 16.5 0.8 1.3 1 0 0 1 1 1 1 Neugrin zf-C3HC4_2 PF13923.1 ETO11706.1 - 0.03 14.3 4.1 0.03 14.3 2.9 3.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RMF PF04957.7 ETO11706.1 - 0.032 13.9 0.2 0.062 12.9 0.1 1.4 1 0 0 1 1 1 0 Ribosome modulation factor DUF2951 PF11166.3 ETO11706.1 - 4.2 7.2 8.5 1.4 8.8 3.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Aldedh PF00171.17 ETO11708.1 - 4.6e-22 77.9 0.5 5e-18 64.6 0.0 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family WD40 PF00400.27 ETO11709.1 - 5.4e-79 257.5 23.5 1.7e-13 49.8 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO11709.1 - 1.7e-12 47.4 0.4 0.00039 20.1 0.1 3.5 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO11709.1 - 2.2e-08 32.6 6.6 0.043 11.9 0.0 5.2 1 1 2 4 4 4 4 Nucleoporin Nup120/160 PD40 PF07676.7 ETO11709.1 - 3.5e-07 29.7 12.4 6.3 6.5 0.0 7.2 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO11709.1 - 7.2e-06 24.5 0.2 0.11 10.7 0.0 3.4 1 1 3 4 4 4 2 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 ETO11709.1 - 1.5e-05 23.9 0.6 9.1e-05 21.4 0.3 1.9 1 1 1 2 2 2 1 Coatomer WD associated region DUF3601 PF12208.3 ETO11709.1 - 0.00017 21.4 0.0 4.3 7.3 0.0 5.1 2 1 2 5 5 5 1 Domain of unknown function (DUF3601) NodS PF05401.6 ETO11709.1 - 0.0011 18.4 0.0 0.0056 16.0 0.0 2.3 3 0 0 3 3 3 1 Nodulation protein S (NodS) DPPIV_N PF00930.16 ETO11709.1 - 0.0023 16.5 0.1 1 7.8 0.0 3.7 2 2 1 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nucleoporin_N PF08801.6 ETO11709.1 - 0.0024 16.7 11.2 0.25 10.0 0.1 5.4 1 1 2 4 4 4 1 Nup133 N terminal like Resistin PF06954.6 ETO11709.1 - 0.0032 17.6 2.7 6.5 7.1 0.0 4.5 3 2 2 5 5 5 1 Resistin Str_synth PF03088.11 ETO11709.1 - 0.0074 16.2 0.0 2 8.4 0.0 3.9 3 2 2 5 5 5 1 Strictosidine synthase DUF1258 PF06869.7 ETO11709.1 - 0.019 14.0 3.0 4.6 6.2 0.1 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1258) OSR1_C PF12202.3 ETO11709.1 - 0.042 13.4 0.7 0.73 9.5 0.0 2.4 2 0 0 2 2 2 0 Oxidative-stress-responsive kinase 1 C terminal DUF1652 PF07865.6 ETO11709.1 - 0.044 13.3 0.0 14 5.3 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1652) AcetylCoA_hyd_C PF13336.1 ETO11709.1 - 0.085 12.5 0.0 18 4.9 0.0 3.0 3 0 0 3 3 3 0 Acetyl-CoA hydrolase/transferase C-terminal domain Proteasome_A_N PF10584.4 ETO11709.1 - 0.28 10.5 17.0 8.1 5.8 0.0 5.7 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature Ras PF00071.17 ETO11710.1 - 7.9e-05 22.0 0.0 0.00017 21.0 0.0 1.5 1 0 0 1 1 1 1 Ras family Mre11_DNA_bind PF04152.9 ETO11710.1 - 0.028 14.2 7.1 0.06 13.2 5.0 1.6 1 0 0 1 1 1 0 Mre11 DNA-binding presumed domain HNOBA PF07701.9 ETO11710.1 - 0.051 12.7 3.9 0.074 12.2 2.7 1.3 1 0 0 1 1 1 0 Heme NO binding associated Chordopox_A13L PF05961.6 ETO11710.1 - 0.8 9.6 3.4 0.97 9.4 0.7 2.2 2 1 0 2 2 2 0 Chordopoxvirus A13L protein EphA2_TM PF14575.1 ETO11710.1 - 4.2 7.8 5.4 4.3 7.8 2.1 2.3 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Sec62 PF03839.11 ETO11710.1 - 4.4 6.6 13.2 7 5.9 9.1 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 FAM176 PF14851.1 ETO11710.1 - 4.5 6.9 6.9 6.5 6.4 4.8 1.2 1 0 0 1 1 1 0 FAM176 family WD40 PF00400.27 ETO11712.1 - 2.4e-61 201.5 26.7 8.5e-12 44.4 1.5 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO11712.1 - 4.8e-09 34.8 1.3 0.067 11.3 0.0 4.9 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO11712.1 - 3.3e-05 22.8 14.9 0.049 12.3 4.8 3.8 1 1 2 3 3 3 3 Nup133 N terminal like Pfg27 PF09216.5 ETO11712.1 - 0.029 13.9 1.6 0.3 10.6 0.2 2.2 2 0 0 2 2 2 0 Pfg27 Ras PF00071.17 ETO11713.1 - 6e-19 67.9 0.1 1.2e-18 66.9 0.1 1.5 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO11713.1 - 2.7e-09 37.5 0.4 6.6e-09 36.2 0.2 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO11713.1 - 0.00027 20.2 0.4 0.00055 19.2 0.3 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Metallophos PF00149.23 ETO11713.1 - 0.0016 17.9 0.1 0.052 12.9 0.0 2.4 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase Gtr1_RagA PF04670.7 ETO11713.1 - 0.016 14.3 0.1 0.022 13.8 0.1 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region TPR_12 PF13424.1 ETO11714.1 - 3.9e-07 29.9 0.1 7.3e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO11714.1 - 0.0011 18.5 0.1 0.0022 17.5 0.1 1.5 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 ETO11714.1 - 0.0061 16.1 4.4 0.069 12.7 0.4 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO11714.1 - 0.42 10.5 4.1 0.62 9.9 0.6 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.27 ETO11715.1 - 6.5e-18 63.8 6.3 4.4e-10 39.0 0.2 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO11715.1 - 0.0011 17.2 4.5 1.4 6.9 0.0 3.8 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO11715.1 - 0.0013 17.5 2.6 0.0025 16.6 1.8 1.5 1 1 0 1 1 1 1 Nup133 N terminal like EBA-175_VI PF11556.3 ETO11715.1 - 1.4 9.0 4.7 1.6 8.8 0.1 2.7 3 0 0 3 3 3 0 Erythrocyte binding antigen 175 WD40 PF00400.27 ETO11716.1 - 6.2e-35 117.8 7.7 2.7e-11 42.9 0.2 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO11716.1 - 9e-06 24.0 0.6 0.01 14.0 0.1 2.5 1 1 1 2 2 2 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO11716.1 - 0.0097 15.6 1.5 0.14 11.9 0.2 2.4 1 1 1 2 2 2 1 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.27 ETO11717.1 - 1.5e-87 284.6 20.3 2.2e-13 49.5 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO11717.1 - 1.9e-13 50.5 0.9 4.3e-05 23.2 0.1 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 ETO11717.1 - 2.5e-06 26.5 11.0 0.57 8.8 0.3 5.8 1 1 4 5 5 5 4 Nup133 N terminal like DUF1652 PF07865.6 ETO11717.1 - 3e-06 26.7 0.0 2.2 7.9 0.0 5.1 5 0 0 5 5 5 2 Protein of unknown function (DUF1652) PQQ_2 PF13360.1 ETO11717.1 - 7.7e-05 22.2 0.7 0.0043 16.5 0.4 3.1 1 1 1 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO11717.1 - 0.00039 18.8 2.5 0.5 8.6 0.0 2.9 1 1 2 3 3 3 3 Cytochrome D1 heme domain DUF4221 PF13970.1 ETO11717.1 - 0.0053 16.1 0.4 0.37 10.0 0.0 3.5 1 1 2 4 4 4 1 Domain of unknown function (DUF4221) PD40 PF07676.7 ETO11717.1 - 0.0069 16.0 9.4 11 5.8 0.0 6.2 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO11717.1 - 0.0091 16.2 1.2 42 4.5 0.0 5.0 2 2 4 6 6 6 0 Resistin WD40 PF00400.27 ETO11718.1 - 7.9e-72 234.7 14.8 6.9e-11 41.5 0.1 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO11718.1 - 7.8e-06 24.8 4.8 0.92 8.1 0.4 5.0 1 1 2 3 3 3 3 Nup133 N terminal like Nup160 PF11715.3 ETO11718.1 - 1.4e-05 23.4 3.5 0.046 11.8 0.1 4.3 1 1 4 5 5 5 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO11718.1 - 0.00039 18.8 2.9 0.7 8.1 0.0 4.3 3 1 2 5 5 5 2 Cytochrome D1 heme domain PD40 PF07676.7 ETO11718.1 - 0.00071 19.1 7.3 4 7.2 0.1 5.7 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat HPS3_N PF14761.1 ETO11718.1 - 0.012 15.0 0.0 11 5.4 0.0 3.4 4 0 0 4 4 4 0 Hermansky-Pudlak syndrome 3 Resistin PF06954.6 ETO11718.1 - 0.07 13.4 0.0 29 5.0 0.0 3.4 3 0 0 3 3 3 0 Resistin Proteasome_A_N PF10584.4 ETO11718.1 - 4.8 6.5 11.6 5.3 6.4 0.0 4.9 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature RNA_pol_Rpb2_2 PF04561.9 ETO11719.1 - 0.044 13.1 0.1 6.4 6.1 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 2 Aldedh PF00171.17 ETO11720.1 - 7.5e-93 311.3 0.0 3.7e-90 302.5 0.0 2.2 1 1 0 1 1 1 1 Aldehyde dehydrogenase family WD40 PF00400.27 ETO11721.1 - 4.6e-23 80.2 7.3 2.1e-07 30.5 0.3 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO11721.1 - 9.8e-05 20.6 0.2 0.025 12.7 0.1 2.6 1 1 1 2 2 2 2 Nucleoporin Nup120/160 VWA_2 PF13519.1 ETO11722.1 - 2e-11 44.2 0.0 2.9e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1330 PF07045.6 ETO11723.1 - 0.0057 16.4 0.0 0.0082 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1330) DUF2968 PF11180.3 ETO11723.1 - 0.082 12.2 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF3546 PF12066.3 ETO11725.1 - 0.032 14.2 0.3 0.051 13.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3546) DUF1014 PF06244.7 ETO11725.1 - 0.045 13.9 0.1 0.067 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1014) SH3BP5 PF05276.9 ETO11725.1 - 0.077 12.2 0.8 0.092 12.0 0.5 1.1 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) Ribosomal_L32e PF01655.13 ETO11726.1 - 0.069 13.2 0.2 0.4 10.7 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L32 TP6A_N PF04406.9 ETO11726.1 - 0.08 12.6 0.5 1.3 8.7 0.1 2.8 2 0 0 2 2 2 0 Type IIB DNA topoisomerase DUF2312 PF10073.4 ETO11726.1 - 0.12 11.7 3.5 1.7 8.0 0.0 3.6 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2312) Spectrin PF00435.16 ETO11726.1 - 2.9 8.2 11.4 1.4 9.2 0.7 3.3 3 1 0 3 3 3 0 Spectrin repeat Scm3 PF10384.4 ETO11727.1 - 0.017 14.5 4.8 1.1 8.7 0.0 2.8 3 0 0 3 3 3 0 Centromere protein Scm3 TPR_12 PF13424.1 ETO11728.1 - 3.9e-131 427.2 54.4 3.4e-22 78.1 0.6 11.8 5 4 5 12 12 12 12 Tetratricopeptide repeat TPR_11 PF13414.1 ETO11728.1 - 4.9e-81 266.3 50.0 1.9e-12 46.6 1.1 10.3 10 0 0 10 10 10 9 TPR repeat TPR_10 PF13374.1 ETO11728.1 - 3.2e-71 233.4 0.8 9.7e-06 25.3 0.0 17.4 18 0 0 18 18 18 13 Tetratricopeptide repeat TPR_1 PF00515.23 ETO11728.1 - 1.6e-68 223.6 92.7 2.5e-07 29.9 0.5 19.9 19 1 0 19 19 19 13 Tetratricopeptide repeat TPR_2 PF07719.12 ETO11728.1 - 1.3e-57 187.1 78.5 5.8e-06 25.8 0.4 17.9 18 0 0 18 18 17 13 Tetratricopeptide repeat TPR_7 PF13176.1 ETO11728.1 - 8.5e-57 184.5 29.5 4.7e-05 22.8 0.0 16.5 17 0 0 17 17 17 12 Tetratricopeptide repeat TPR_8 PF13181.1 ETO11728.1 - 1.2e-46 153.0 95.4 1.7e-06 27.3 0.3 17.0 17 1 0 17 17 17 11 Tetratricopeptide repeat TPR_16 PF13432.1 ETO11728.1 - 1.1e-27 96.0 10.1 0.039 14.6 0.0 10.8 7 3 2 10 10 10 6 Tetratricopeptide repeat TPR_17 PF13431.1 ETO11728.1 - 3.3e-24 83.0 29.9 0.02 15.0 0.1 14.9 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_14 PF13428.1 ETO11728.1 - 1.9e-18 65.2 1.5 4.1 8.2 0.0 12.8 14 1 1 15 15 12 3 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO11728.1 - 2.4e-18 65.0 1.0 0.0031 16.7 0.0 10.6 12 0 0 12 12 12 3 SHNi-TPR TPR_19 PF14559.1 ETO11728.1 - 7.3e-13 48.6 15.3 0.00096 19.4 0.1 8.5 9 1 2 11 11 10 4 Tetratricopeptide repeat TPR_6 PF13174.1 ETO11728.1 - 1.6e-08 34.4 30.5 1.2 9.7 0.0 12.5 15 0 0 15 15 13 3 Tetratricopeptide repeat MIT PF04212.13 ETO11728.1 - 0.037 13.9 45.9 0.64 9.9 0.1 12.7 15 0 0 15 15 15 0 MIT (microtubule interacting and transport) domain PPR PF01535.15 ETO11728.1 - 3.8 7.6 21.1 51 4.1 0.0 9.6 11 0 0 11 11 11 0 PPR repeat U-box PF04564.10 ETO11729.1 - 2.9e-05 23.9 0.1 8.4e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 U-box domain Mcp5_PH PF12814.2 ETO11730.1 - 0.0023 17.8 0.1 0.0031 17.4 0.1 1.2 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology zf-met PF12874.2 ETO11730.1 - 0.019 15.1 4.4 0.55 10.5 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF2890 PF11081.3 ETO11731.1 - 0.00077 19.5 1.2 0.0013 18.8 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2890) CDC45 PF02724.9 ETO11731.1 - 0.024 12.6 1.0 0.033 12.2 0.7 1.2 1 0 0 1 1 1 0 CDC45-like protein BSP_II PF05432.6 ETO11731.1 - 0.078 12.2 16.8 0.12 11.5 11.6 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Nop14 PF04147.7 ETO11731.1 - 3.7 5.3 15.0 5.4 4.8 10.4 1.1 1 0 0 1 1 1 0 Nop14-like family DAP PF15228.1 ETO11731.1 - 4.8 7.9 5.9 50 4.7 1.1 2.5 2 0 0 2 2 2 0 Death-associated protein Paf1 PF03985.8 ETO11731.1 - 5.4 5.6 19.1 9.1 4.8 0.0 2.1 2 0 0 2 2 2 0 Paf1 Daxx PF03344.10 ETO11731.1 - 7.8 4.8 15.9 12 4.1 11.0 1.2 1 0 0 1 1 1 0 Daxx Family Pox_Ag35 PF03286.9 ETO11731.1 - 9.8 5.6 11.8 22 4.5 8.1 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RRF_GI PF12614.3 ETO11732.1 - 1.6 8.5 6.2 1.2 8.9 0.9 2.7 1 1 1 3 3 3 0 Ribosome recycling factor EF-hand_1 PF00036.27 ETO11733.1 - 3e-22 76.1 8.9 4e-06 25.7 0.3 5.5 6 0 0 6 6 6 3 EF hand EF-hand_7 PF13499.1 ETO11733.1 - 7.5e-21 74.0 7.1 2.4e-13 49.9 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO11733.1 - 6e-17 59.9 9.8 5.4e-05 22.7 0.3 4.7 5 1 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.1 ETO11733.1 - 4.7e-16 57.3 9.1 0.0002 20.5 0.2 4.6 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 ETO11733.1 - 8.1e-15 54.1 5.9 7.7e-07 28.6 0.0 3.4 2 2 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 ETO11733.1 - 6.7e-05 22.8 1.1 0.019 14.9 0.1 2.6 1 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 ETO11733.1 - 0.0063 16.2 2.4 0.44 10.2 0.0 3.1 1 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand PMBR PF09373.5 ETO11733.1 - 0.053 13.4 0.5 4.9 7.2 0.0 3.9 5 0 0 5 5 5 0 Pseudomurein-binding repeat FDX-ACB PF03147.9 ETO11733.1 - 0.13 12.4 1.9 3.5 7.8 0.0 3.1 3 1 1 4 4 4 0 Ferredoxin-fold anticodon binding domain Kelch_1 PF01344.20 ETO11734.1 - 4.6e-05 22.8 0.7 0.002 17.6 0.0 3.5 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 ETO11734.1 - 7.1e-05 22.8 3.6 0.017 15.2 0.0 4.3 3 2 2 5 5 5 1 Kelch motif Kelch_5 PF13854.1 ETO11734.1 - 0.0003 20.6 3.4 0.098 12.6 0.0 4.2 4 0 0 4 4 4 1 Kelch motif Pyrophosphatase PF00719.14 ETO11734.1 - 0.0079 15.6 0.4 0.013 14.9 0.3 1.3 1 0 0 1 1 1 1 Inorganic pyrophosphatase Kelch_3 PF13415.1 ETO11734.1 - 0.021 15.0 0.4 0.12 12.5 0.0 2.5 3 0 0 3 3 3 0 Galactose oxidase, central domain Serpin PF00079.15 ETO11736.1 - 1.7e-06 27.4 0.0 3.7e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 Serpin (serine protease inhibitor) DUF2829 PF11195.3 ETO11736.1 - 0.0026 18.1 0.1 0.0044 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2829) Ion_trans PF00520.26 ETO11737.1 - 5.3e-19 68.2 48.4 2.4e-18 66.1 17.1 2.5 2 0 0 2 2 2 2 Ion transport protein EF-hand_6 PF13405.1 ETO11737.1 - 0.00038 20.0 1.1 0.2 11.6 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 ETO11737.1 - 0.00054 20.0 1.5 0.17 12.0 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 ETO11737.1 - 0.0053 15.9 2.4 0.24 10.7 0.4 2.7 2 0 0 2 2 2 1 EF hand COX6B PF02297.12 ETO11737.1 - 0.049 13.6 2.2 0.12 12.4 1.5 1.7 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb FANCL_C PF11793.3 ETO11737.1 - 0.15 12.0 0.3 0.8 9.7 0.2 2.2 2 0 0 2 2 2 0 FANCL C-terminal domain WD40 PF00400.27 ETO11740.1 - 1.1e-25 88.4 9.0 8.9e-11 41.2 0.3 4.1 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO11740.1 - 0.00017 19.9 0.5 2.2 6.3 0.0 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO11740.1 - 0.003 16.3 2.5 0.15 10.8 0.7 2.7 1 1 2 3 3 3 1 Nup133 N terminal like eIF2A PF08662.6 ETO11740.1 - 0.044 13.5 0.3 0.99 9.0 0.2 2.4 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A SurA_N_3 PF13624.1 ETO11742.1 - 0.092 12.7 0.2 0.15 12.0 0.2 1.2 1 0 0 1 1 1 0 SurA N-terminal domain C1_3 PF07649.7 ETO11743.1 - 0.41 10.7 4.9 0.62 10.1 1.9 2.3 2 0 0 2 2 2 0 C1-like domain ABC_transp_aux PF09822.4 ETO11744.1 - 0.014 14.8 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 ABC-type uncharacterized transport system Peptidase_S8 PF00082.17 ETO11745.1 - 5.1e-14 52.0 0.0 6.1e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Subtilase family AAA_34 PF13872.1 ETO11745.1 - 0.062 12.0 0.3 0.21 10.3 0.1 1.8 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 MIP-T3 PF10243.4 ETO11746.1 - 1.2 7.5 33.5 1.3 7.3 23.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PLRV_ORF5 PF01690.12 ETO11746.1 - 5.8 5.9 21.8 6.8 5.7 15.1 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein NMT_C PF02799.10 ETO11747.1 - 7.1e-73 244.0 1.0 1e-72 243.5 0.7 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 ETO11747.1 - 4.6e-33 114.1 4.2 5.4e-28 97.6 0.6 2.4 1 1 1 2 2 2 2 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain TrkA_C PF02080.16 ETO11748.1 - 1.8e-08 33.8 0.0 2.8e-07 30.0 0.0 2.7 2 1 1 3 3 3 1 TrkA-C domain MCLC PF05934.6 ETO11748.1 - 0.12 10.5 0.8 0.19 10.0 0.6 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Hemerythrin PF01814.18 ETO11750.1 - 0.003 17.7 0.3 0.0043 17.2 0.2 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Hemerythrin PF01814.18 ETO11751.1 - 7.4e-07 29.4 0.3 9.9e-07 28.9 0.2 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF3853 PF12964.2 ETO11753.1 - 0.015 15.1 0.2 0.045 13.5 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3853) DUF4119 PF13494.1 ETO11753.1 - 0.033 14.1 2.0 0.041 13.8 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF4119) MCR_beta PF02241.13 ETO11753.1 - 0.14 11.3 0.1 0.14 11.3 0.1 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain BRCT PF00533.21 ETO11753.1 - 0.33 11.1 2.2 0.42 10.7 0.7 1.9 1 1 1 2 2 2 0 BRCA1 C Terminus (BRCT) domain CRS1_YhbY PF01985.16 ETO11753.1 - 0.58 10.1 3.0 7.4 6.6 0.6 2.1 1 1 1 2 2 2 0 CRS1 / YhbY (CRM) domain NAP PF00956.13 ETO11754.1 - 0.12 11.4 2.9 0.055 12.5 0.6 1.4 2 0 0 2 2 2 0 Nucleosome assembly protein (NAP) WD40 PF00400.27 ETO11755.1 - 1.3e-59 196.0 16.2 1.7e-10 40.3 0.1 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO11755.1 - 4.1e-09 35.1 1.9 0.00042 18.5 0.1 3.8 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Josephin PF02099.12 ETO11756.1 - 1.7e-11 43.9 0.1 2.6e-11 43.4 0.1 1.2 1 0 0 1 1 1 1 Josephin Fcf1 PF04900.7 ETO11757.1 - 4.8e-33 113.2 0.8 4.8e-33 113.2 0.6 1.7 2 0 0 2 2 2 1 Fcf1 PIN PF01850.16 ETO11757.1 - 0.0022 18.3 1.9 0.11 12.7 1.3 2.2 1 1 0 1 1 1 1 PIN domain v110 PF01639.12 ETO11758.1 - 0.027 14.0 0.1 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 Viral family 110 NOA36 PF06524.7 ETO11759.1 - 0.00023 20.5 11.6 0.0005 19.4 8.0 1.6 1 0 0 1 1 1 1 NOA36 protein Nucleoplasmin PF03066.10 ETO11759.1 - 9.3 5.7 12.7 29 4.1 8.8 1.8 1 0 0 1 1 1 0 Nucleoplasmin SGL PF08450.7 ETO11760.1 - 5.4e-06 25.9 0.1 1.1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 ETO11760.1 - 0.016 15.1 0.0 0.13 12.2 0.0 2.3 2 0 0 2 2 2 0 Strictosidine synthase Arylesterase PF01731.15 ETO11760.1 - 0.059 13.3 0.4 0.75 9.8 0.4 2.6 2 1 0 2 2 2 0 Arylesterase Alg6_Alg8 PF03155.10 ETO11761.1 - 7.6e-107 358.0 32.3 1.3e-104 350.6 22.4 3.4 1 1 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family DUF2029 PF09594.5 ETO11761.1 - 0.31 10.5 4.7 0.24 10.8 1.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2029) WD40 PF00400.27 ETO11762.1 - 4.4e-31 105.6 19.7 1.8e-09 37.1 0.2 6.1 5 1 0 5 5 5 4 WD domain, G-beta repeat WD40 PF00400.27 ETO11763.1 - 3.5e-19 67.9 4.2 6.1e-10 38.5 0.4 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO11763.1 - 0.00011 20.4 0.6 0.0002 19.6 0.3 1.3 1 1 0 1 1 1 1 Nucleoporin Nup120/160 DUF1430 PF07242.6 ETO11763.1 - 0.093 12.8 1.2 0.14 12.2 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1430) Kelch_6 PF13964.1 ETO11765.1 - 0.00052 20.0 2.6 0.02 15.0 0.1 4.0 4 1 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 ETO11765.1 - 0.0027 17.6 0.8 0.012 15.5 0.1 2.5 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 ETO11765.1 - 0.006 16.1 0.3 0.9 9.1 0.0 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO11765.1 - 0.037 13.8 1.1 0.37 10.6 0.0 3.1 4 1 0 4 4 4 0 Kelch motif Kelch_3 PF13415.1 ETO11765.1 - 0.1 12.8 0.0 0.76 10.0 0.0 2.5 2 0 0 2 2 2 0 Galactose oxidase, central domain SMI1_KNR4 PF09346.5 ETO11765.1 - 0.17 11.9 1.4 0.27 11.2 0.6 1.6 1 1 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) WD40 PF00400.27 ETO11766.1 - 7.3e-15 54.2 12.8 2.8e-09 36.5 0.9 3.8 3 2 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO11766.1 - 0.0025 16.0 0.0 1.1 7.2 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 BHD_1 PF10403.4 ETO11766.1 - 0.18 11.3 0.9 1.8 8.1 0.3 2.3 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 1 WD40 PF00400.27 ETO11767.1 - 1.8e-32 110.0 12.6 4.6e-13 48.4 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO11767.1 - 6.6e-10 37.7 0.7 0.00025 19.3 0.1 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO11767.1 - 0.00039 20.1 1.1 0.017 14.8 0.1 2.1 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A POT1 PF02765.12 ETO11767.1 - 0.44 10.4 3.6 0.95 9.3 2.5 1.7 1 1 0 1 1 1 0 Telomeric single stranded DNA binding POT1/CDC13 UCH PF00443.24 ETO11768.1 - 8.3e-10 38.2 0.1 8.3e-10 38.2 0.1 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO11768.1 - 5.3e-07 29.3 0.2 5.3e-07 29.3 0.2 2.5 2 2 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Skp1_POZ PF03931.10 ETO11768.1 - 0.019 15.0 0.3 0.19 11.8 0.0 2.5 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain Tau95 PF09734.4 ETO11769.1 - 0.00036 19.9 1.8 0.0005 19.4 1.2 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit ProQ PF04352.8 ETO11769.1 - 0.9 9.1 7.9 3.4 7.3 0.1 2.5 2 0 0 2 2 2 0 ProQ/FINO family Ycf1 PF05758.7 ETO11769.1 - 2.8 5.5 10.7 0.19 9.3 3.5 1.7 2 0 0 2 2 2 0 Ycf1 Spore_III_AF PF09581.5 ETO11769.1 - 5.1 6.9 16.8 0.38 10.5 8.0 1.8 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) Spore_coat_CotO PF14153.1 ETO11769.1 - 9.7 5.5 20.3 0.53 9.7 8.6 2.3 2 0 0 2 2 2 0 Spore coat protein CotO TPR_12 PF13424.1 ETO11770.1 - 0.069 13.0 2.9 4.8 7.1 0.3 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat zf-HIT PF04438.11 ETO11770.1 - 1.2 8.7 7.3 0.16 11.6 0.7 2.6 2 0 0 2 2 2 0 HIT zinc finger WD40 PF00400.27 ETO11771.1 - 4.6e-23 80.1 14.3 2.1e-09 36.9 0.6 4.4 4 1 0 4 4 4 4 WD domain, G-beta repeat Rhodanese PF00581.15 ETO11773.1 - 1.4e-18 67.2 0.2 3.5e-08 33.7 0.0 2.8 2 0 0 2 2 2 2 Rhodanese-like domain Kelch_6 PF13964.1 ETO11774.1 - 5.6e-05 23.1 0.3 0.0018 18.3 0.3 2.4 1 1 1 2 2 2 1 Kelch motif Kelch_2 PF07646.10 ETO11774.1 - 5.9e-05 22.6 0.2 0.00087 18.9 0.1 2.4 2 1 0 2 2 2 1 Kelch motif Kelch_1 PF01344.20 ETO11774.1 - 0.00074 19.0 0.8 0.00074 19.0 0.6 2.0 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 ETO11774.1 - 0.011 15.8 0.1 0.038 14.1 0.0 1.8 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO11774.1 - 0.04 13.8 0.4 0.067 13.1 0.3 1.4 1 0 0 1 1 1 0 Kelch motif NYD-SP28_assoc PF14775.1 ETO11774.1 - 0.065 12.9 0.1 0.12 12.0 0.0 1.5 1 1 0 1 1 1 0 Sperm tail C-terminal domain Kelch_4 PF13418.1 ETO11774.1 - 0.067 12.9 0.0 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 Galactose oxidase, central domain WD40 PF00400.27 ETO11775.1 - 6e-43 143.2 13.3 1.6e-11 43.6 0.1 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO11775.1 - 3.7e-07 28.6 0.4 0.0054 14.9 0.0 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO11775.1 - 5.8e-05 22.8 0.0 0.00011 21.9 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 ETO11775.1 - 0.0073 15.0 2.2 2.5 6.7 0.0 3.3 1 1 2 4 4 4 3 Nup133 N terminal like Ricin_B_lectin PF00652.17 ETO11775.1 - 0.025 14.6 1.1 0.42 10.6 0.7 2.3 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain PD40 PF07676.7 ETO11775.1 - 0.039 13.6 1.8 3.7 7.3 0.1 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 ETO11776.1 - 4.8e-16 57.9 0.9 1.1e-09 37.8 0.0 2.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO11776.1 - 0.0056 14.8 0.0 0.027 12.6 0.0 1.8 1 1 0 1 1 1 1 Nucleoporin Nup120/160 DUF2480 PF10652.4 ETO11776.1 - 0.06 12.9 0.0 0.08 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2480) HAD PF12710.2 ETO11776.1 - 0.12 12.5 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase NOP5NT PF08156.8 ETO11777.1 - 5.6e-18 64.8 1.4 1.3e-17 63.6 1.0 1.7 1 0 0 1 1 1 1 NOP5NT (NUC127) domain NOSIC PF08060.8 ETO11778.1 - 4.4e-26 90.4 0.2 8.7e-26 89.4 0.1 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain Bestrophin PF01062.16 ETO11778.1 - 0.022 13.7 0.1 0.025 13.5 0.0 1.1 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel Nop PF01798.13 ETO11779.1 - 4.9e-38 129.7 0.2 4.9e-38 129.7 0.1 1.8 2 0 0 2 2 2 1 Putative snoRNA binding domain Ecl1 PF12855.2 ETO11779.1 - 0.063 12.5 0.1 0.17 11.2 0.0 1.7 1 0 0 1 1 1 0 Life-span regulatory factor Zip PF02535.17 ETO11779.1 - 0.63 8.9 2.2 0.75 8.7 1.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Hid1 PF12722.2 ETO11779.1 - 5.8 4.4 14.3 6.7 4.2 9.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LRAT PF04970.8 ETO11780.1 - 0.067 13.1 0.1 0.092 12.7 0.0 1.3 1 1 0 1 1 1 0 Lecithin retinol acyltransferase DUF943 PF06092.7 ETO11780.1 - 0.12 11.6 0.9 0.25 10.6 0.1 1.8 2 0 0 2 2 2 0 Enterobacterial putative membrane protein (DUF943) WD40 PF00400.27 ETO11782.1 - 1.4e-11 43.8 2.1 2.5e-10 39.8 0.1 2.8 3 0 0 3 3 3 1 WD domain, G-beta repeat DAOA PF15199.1 ETO11782.1 - 0.058 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 D-amino acid oxidase activator ubiquitin PF00240.18 ETO11783.1 - 0.16 11.3 1.3 0.29 10.5 0.1 2.0 2 0 0 2 2 2 0 Ubiquitin family WD40 PF00400.27 ETO11785.1 - 2.7e-69 226.7 17.3 3.1e-11 42.6 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat PQQ_2 PF13360.1 ETO11785.1 - 5.5e-08 32.5 0.0 1.1e-05 25.0 0.0 3.0 1 1 1 3 3 3 2 PQQ-like domain Nup160 PF11715.3 ETO11785.1 - 7.2e-08 31.0 4.6 0.19 9.8 0.0 5.6 1 1 5 6 6 6 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO11785.1 - 5.9e-05 21.5 0.6 0.038 12.3 0.1 3.0 1 1 3 4 4 4 2 Cytochrome D1 heme domain PD40 PF07676.7 ETO11785.1 - 0.0014 18.2 0.4 5.1 6.8 0.0 3.9 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Hira PF07569.6 ETO11785.1 - 0.014 14.6 1.5 4.6 6.3 0.0 4.3 3 2 2 5 5 5 0 TUP1-like enhancer of split Resistin PF06954.6 ETO11785.1 - 0.084 13.1 0.4 14 6.0 0.0 3.4 2 1 1 3 3 3 0 Resistin WD40 PF00400.27 ETO11786.1 - 1.3e-46 154.8 5.7 1.2e-12 47.1 0.0 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 ETO11786.1 - 1.6e-09 37.7 0.2 8.8e-07 28.8 0.1 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO11786.1 - 1.4e-06 27.7 2.4 3.4 7.4 0.1 5.1 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO11786.1 - 6.2e-06 24.6 3.7 0.025 12.7 0.0 3.7 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO11786.1 - 6.7e-05 21.8 2.6 0.043 12.5 0.0 3.4 1 1 3 4 4 4 1 Nup133 N terminal like Coatomer_WDAD PF04053.9 ETO11786.1 - 0.00028 19.8 0.7 0.0031 16.3 0.3 2.0 1 1 1 2 2 2 2 Coatomer WD associated region Cytochrom_D1 PF02239.11 ETO11786.1 - 0.00093 17.5 0.3 0.8 7.9 0.0 2.2 1 1 0 2 2 2 1 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO11786.1 - 0.0014 18.1 0.2 0.0024 17.3 0.1 1.3 1 1 0 1 1 1 1 PQQ-like domain MMS1_N PF10433.4 ETO11786.1 - 0.0025 16.0 0.0 0.085 10.9 0.0 2.0 1 1 1 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF2314 PF10077.4 ETO11786.1 - 0.022 14.7 0.3 1.5 8.8 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2314) DUF1900 PF08954.6 ETO11786.1 - 0.11 12.0 0.0 1.8 8.0 0.0 2.6 1 1 1 3 3 3 0 Domain of unknown function (DUF1900) PQQ PF01011.16 ETO11786.1 - 0.12 11.9 0.3 1.1 8.8 0.0 2.7 3 0 0 3 3 3 0 PQQ enzyme repeat Proteasome_A_N PF10584.4 ETO11786.1 - 0.53 9.6 6.6 13 5.1 0.2 3.9 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature VWA_2 PF13519.1 ETO11788.1 - 1.9e-07 31.3 0.0 3.2e-05 24.0 0.0 2.2 1 1 0 1 1 1 1 von Willebrand factor type A domain Peptidase_C25 PF01364.13 ETO11788.1 - 0.0044 16.0 0.0 0.0062 15.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C25 DUF640 PF04852.7 ETO11788.1 - 0.0087 16.2 0.3 1.1 9.4 0.0 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF640) HAUS5 PF14817.1 ETO11788.1 - 0.0097 14.5 0.0 0.016 13.8 0.0 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 WD40 PF00400.27 ETO11790.1 - 3.3e-22 77.4 12.1 8.8e-08 31.7 0.0 5.2 5 1 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO11790.1 - 0.0034 15.5 0.5 0.33 9.0 0.4 2.9 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO11790.1 - 0.014 14.1 2.3 0.023 13.4 1.6 1.4 1 1 0 1 1 1 0 Nup133 N terminal like Ricin_B_lectin PF00652.17 ETO11790.1 - 0.31 11.0 2.2 0.31 11.0 0.6 1.7 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain CUE PF02845.11 ETO11791.1 - 0.0097 15.3 0.0 1.1 8.7 0.0 2.7 2 0 0 2 2 2 2 CUE domain HeLo PF14479.1 ETO11791.1 - 0.011 15.5 0.9 0.015 15.0 0.6 1.2 1 0 0 1 1 1 0 Prion-inhibition and propagation LRR_6 PF13516.1 ETO11793.1 - 0.1 12.7 1.1 7.9 6.8 0.3 3.6 2 0 0 2 2 2 0 Leucine Rich repeat Peptidase_C14 PF00656.17 ETO11794.1 - 0.00028 20.6 0.1 0.00035 20.3 0.1 1.1 1 0 0 1 1 1 1 Caspase domain COMP PF11598.3 ETO11794.1 - 0.092 12.8 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein ComC PF03047.9 ETO11795.1 - 0.061 12.7 1.0 1.7 8.1 0.0 2.7 2 0 0 2 2 2 0 COMC family WD40 PF00400.27 ETO11796.1 - 6.9e-34 114.5 4.2 5.3e-11 41.9 0.0 7.3 8 0 0 8 8 8 5 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO11796.1 - 0.00083 19.4 5.0 0.74 10.0 0.1 4.0 3 0 0 3 3 3 2 Kelch motif Nup160 PF11715.3 ETO11796.1 - 0.0018 16.4 1.0 0.13 10.3 0.1 3.0 1 1 0 2 2 2 2 Nucleoporin Nup120/160 Kelch_5 PF13854.1 ETO11796.1 - 0.11 12.4 5.6 2.1 8.3 0.1 3.6 3 1 0 3 3 3 0 Kelch motif Kelch_4 PF13418.1 ETO11796.1 - 0.15 11.8 2.6 1.8 8.3 0.0 3.4 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO11796.1 - 0.33 10.7 3.5 39 4.2 0.0 4.4 5 0 0 5 5 5 0 Kelch motif CENP-P PF13096.1 ETO11797.1 - 0.032 13.5 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P DUF778 PF05608.7 ETO11798.1 - 0.038 13.9 0.7 1.2e+02 2.5 0.0 3.9 2 2 1 3 3 3 0 Protein of unknown function (DUF778) ELL PF10390.4 ETO11800.1 - 0.0076 15.4 2.2 0.014 14.5 1.6 1.5 1 0 0 1 1 1 1 RNA polymerase II elongation factor ELL MRP-L46 PF11788.3 ETO11800.1 - 0.65 10.6 3.5 0.44 11.2 0.6 2.0 2 1 0 2 2 2 0 39S mitochondrial ribosomal protein L46 Histone PF00125.19 ETO11801.1 - 4.7e-30 103.5 0.4 7.5e-30 102.8 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 ETO11801.1 - 5e-06 26.6 0.0 8.4e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 ETO11801.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 ETO11801.1 - 0.016 14.5 0.4 0.021 14.0 0.3 1.4 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 ETO11801.1 - 0.016 14.8 0.1 0.041 13.6 0.1 1.7 1 1 0 1 1 1 0 Bromodomain associated TctB PF07331.6 ETO11802.1 - 3.9 7.1 10.9 0.28 10.8 0.4 2.5 3 0 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family DUF1469 PF07332.6 ETO11802.1 - 4.3 7.0 8.8 0.16 11.7 0.8 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1469) UBA PF00627.26 ETO11803.1 - 0.016 15.0 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain RecX PF02631.11 ETO11803.1 - 0.12 12.5 0.1 0.17 12.0 0.1 1.2 1 0 0 1 1 1 0 RecX family WD40 PF00400.27 ETO11805.1 - 2.2e-70 230.2 19.4 4.4e-12 45.3 0.7 7.5 7 1 1 8 8 8 7 WD domain, G-beta repeat PD40 PF07676.7 ETO11805.1 - 2e-09 36.8 1.3 0.56 9.9 0.0 6.2 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO11805.1 - 2e-08 32.8 1.0 0.013 13.7 0.3 4.1 2 1 0 3 3 3 2 Nucleoporin Nup120/160 Proteasome_A_N PF10584.4 ETO11805.1 - 0.00061 19.0 4.9 16 4.9 0.0 6.3 7 0 0 7 7 7 1 Proteasome subunit A N-terminal signature Coatomer_WDAD PF04053.9 ETO11805.1 - 0.00096 18.0 0.1 0.0024 16.7 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region Resistin PF06954.6 ETO11805.1 - 0.0035 17.5 0.1 9.5 6.5 0.0 3.4 3 0 0 3 3 3 1 Resistin DPPIV_N PF00930.16 ETO11805.1 - 0.0044 15.6 0.0 3.6 6.0 0.0 3.5 2 1 0 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF2963 PF11178.3 ETO11805.1 - 0.011 15.1 0.1 1.4 8.3 0.0 3.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2963) Peptidase_M44 PF03410.8 ETO11805.1 - 0.029 12.6 0.4 0.037 12.2 0.3 1.2 1 0 0 1 1 1 0 Protein G1 Ribosomal_L36e PF01158.13 ETO11807.1 - 5.6e-19 67.9 11.1 3e-16 59.1 3.6 2.5 1 1 1 2 2 2 2 Ribosomal protein L36e DUF3106 PF11304.3 ETO11807.1 - 0.19 12.1 4.0 0.33 11.3 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) PBP1_TM PF14812.1 ETO11808.1 - 0.3 11.4 5.7 0.061 13.6 0.9 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WD40 PF00400.27 ETO11810.1 - 5.6e-56 184.5 19.9 2.8e-12 45.9 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO11810.1 - 4.9e-08 31.5 0.4 0.57 8.2 0.0 4.3 3 1 1 4 4 4 4 Nucleoporin Nup120/160 FKBP_N PF01346.13 ETO11811.1 - 0.012 15.6 1.4 0.017 15.1 1.0 1.2 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF1819 PF08849.6 ETO11813.1 - 0.041 13.2 0.2 0.049 13.0 0.1 1.2 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) Tmpp129 PF10272.4 ETO11814.1 - 0.043 12.5 0.1 0.053 12.2 0.1 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor DUF3608 PF12257.3 ETO11815.1 - 0.18 10.6 2.3 0.22 10.3 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3608) L_lactis_ph-MCP PF06673.6 ETO11815.1 - 0.21 10.2 3.6 0.3 9.8 2.5 1.3 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein Ax_dynein_light PF10211.4 ETO11815.1 - 0.92 9.3 35.2 3.9 7.2 10.3 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain Tropomyosin_1 PF12718.2 ETO11815.1 - 1.8 8.4 38.8 4.5 7.1 8.5 3.1 2 1 1 3 3 3 0 Tropomyosin like ApoO PF09769.4 ETO11815.1 - 2.1 8.0 9.4 0.16 11.6 1.3 2.1 1 1 1 2 2 2 0 Apolipoprotein O Mnd1 PF03962.10 ETO11815.1 - 5.9 6.5 36.8 2.8 7.5 9.9 2.1 1 1 1 2 2 2 0 Mnd1 family MAP7 PF05672.6 ETO11815.1 - 6.7 6.0 44.0 0.77 9.1 24.4 2.1 1 1 1 2 2 2 0 MAP7 (E-MAP-115) family Usp PF00582.21 ETO11815.1 - 9.4 6.4 7.1 4.8 7.3 0.2 2.1 2 0 0 2 2 2 0 Universal stress protein family DUF3584 PF12128.3 ETO11815.1 - 9.6 3.3 32.5 13 2.9 22.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PCEMA1 PF07418.6 ETO11815.1 - 9.7 5.4 16.0 12 5.1 11.1 1.1 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 Hid1 PF12722.2 ETO11816.1 - 0.39 8.3 9.7 0.49 8.0 6.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MDH PF02315.11 ETO11816.1 - 4.7 7.2 8.2 0.5 10.3 1.7 2.2 2 1 0 2 2 2 0 Methanol dehydrogenase beta subunit Kelch_1 PF01344.20 ETO11818.1 - 0.11 12.0 1.0 0.27 10.7 0.0 2.1 2 1 0 2 2 2 0 Kelch motif Kelch_6 PF13964.1 ETO11819.1 - 4.4e-06 26.6 0.2 0.0022 18.0 0.0 2.5 1 1 1 2 2 2 2 Kelch motif Kelch_1 PF01344.20 ETO11819.1 - 2.1e-05 23.9 0.0 0.012 15.1 0.0 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.1 ETO11819.1 - 0.0037 17.1 0.1 0.091 12.7 0.0 2.3 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.1 ETO11819.1 - 0.0054 16.4 0.0 3.8 7.3 0.0 2.3 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO11819.1 - 0.03 14.1 0.2 0.3 10.9 0.0 2.5 2 1 0 2 2 2 0 Kelch motif SID-1_RNA_chan PF13965.1 ETO11821.1 - 1.3 7.1 5.5 0.53 8.3 1.8 1.6 1 1 1 2 2 2 0 dsRNA-gated channel SID-1 eIF3_p135 PF12807.2 ETO11821.1 - 1.7 8.5 7.2 0.23 11.3 1.8 1.8 1 1 1 2 2 2 0 Translation initiation factor eIF3 subunit 135 Pkinase PF00069.20 ETO11823.1 - 1.7e-36 125.7 0.3 2.1e-19 69.6 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 ETO11823.1 - 1.5e-22 79.9 0.2 1.5e-13 50.3 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase UCR_TM PF02921.9 ETO11823.1 - 0.031 14.5 0.0 0.09 13.0 0.0 1.8 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region CLIP PF12032.3 ETO11827.1 - 0.096 12.7 0.3 0.27 11.3 0.2 1.8 1 0 0 1 1 1 0 Regulatory CLIP domain of proteinases WD40 PF00400.27 ETO11828.1 - 5e-64 210.0 16.4 6e-11 41.7 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO11828.1 - 6.8e-12 44.3 2.4 0.058 11.5 0.0 5.3 2 2 3 5 5 5 4 Nucleoporin Nup120/160 HAP1_N PF04849.8 ETO11828.1 - 0.0062 15.5 12.4 0.0095 14.9 8.6 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region ALMT PF11744.3 ETO11828.1 - 1.9 7.0 5.2 2.5 6.6 3.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter IncA PF04156.9 ETO11828.1 - 3.5 7.1 12.9 5.3 6.5 8.9 1.2 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 ETO11828.1 - 8.8 5.1 12.4 13 4.6 8.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 WD40 PF00400.27 ETO11829.1 - 4e-37 124.7 15.5 1.9e-11 43.3 0.7 4.1 3 1 1 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO11829.1 - 2.6e-07 29.1 2.3 0.001 17.3 0.2 3.0 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Phytochelatin PF05023.9 ETO11830.1 - 2.9e-33 114.6 0.0 6.3e-33 113.5 0.0 1.5 1 0 0 1 1 1 1 Phytochelatin synthase M16C_assoc PF08367.6 ETO11831.1 - 1.6e-31 109.0 8.7 9.7e-31 106.4 6.0 2.3 1 1 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 ETO11831.1 - 8.9e-16 58.0 0.0 7e-11 42.1 0.0 3.1 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 ETO11831.1 - 3.8e-11 42.9 1.2 3.5e-10 39.8 0.0 2.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Flagellin_IN PF07196.8 ETO11831.1 - 0.072 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Flagellin hook IN motif WD40 PF00400.27 ETO11832.1 - 3.3e-83 270.8 24.5 1.6e-14 53.1 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO11832.1 - 3.7e-08 33.3 0.2 0.0003 20.5 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO11832.1 - 2e-07 29.5 8.1 0.44 8.6 0.0 5.7 1 1 5 6 6 6 4 Nucleoporin Nup120/160 PD40 PF07676.7 ETO11832.1 - 0.00023 20.7 6.2 11 5.7 0.0 5.7 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO11832.1 - 0.00033 19.0 1.0 1.8 6.7 0.0 3.0 1 1 2 3 3 3 3 Cytochrome D1 heme domain Resistin PF06954.6 ETO11832.1 - 0.017 15.3 1.2 6.7 7.0 0.0 4.2 2 2 3 5 5 5 0 Resistin DUF4221 PF13970.1 ETO11832.1 - 0.12 11.6 0.8 2.7 7.1 0.0 3.2 2 2 1 3 3 3 0 Domain of unknown function (DUF4221) Hira PF07569.6 ETO11832.1 - 0.18 10.9 0.7 3.2 6.9 0.0 2.8 4 0 0 4 4 4 0 TUP1-like enhancer of split Proteasome_A_N PF10584.4 ETO11832.1 - 0.96 8.8 8.1 16 4.9 0.0 4.9 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature Peptidase_C48 PF02902.14 ETO11833.1 - 5e-20 72.0 10.4 8.7e-20 71.2 5.6 2.6 2 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Actin PF00022.14 ETO11834.1 - 2e-68 230.6 0.1 1.2e-50 172.0 0.0 2.0 2 0 0 2 2 2 2 Actin Exo70 PF03081.10 ETO11835.1 - 5.2e-48 163.7 4.5 6.7e-48 163.3 3.1 1.1 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Pox_A_type_inc PF04508.7 ETO11835.1 - 0.36 10.7 4.1 0.29 11.0 0.2 3.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat ApoLp-III PF07464.6 ETO11835.1 - 1.7 8.6 5.6 0.54 10.2 0.4 2.5 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) TMP_2 PF06791.8 ETO11836.1 - 0.064 12.8 6.8 0.059 12.9 1.7 2.4 2 1 1 3 3 3 0 Prophage tail length tape measure protein CDC27 PF09507.5 ETO11836.1 - 1.6 7.8 48.7 0.04 13.1 28.5 1.9 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Neur_chan_memb PF02932.11 ETO11837.1 - 0.42 10.4 3.4 3 7.6 2.4 2.1 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DBP10CT PF08147.7 ETO11838.1 - 0.028 14.2 0.0 0.028 14.2 0.0 1.8 2 0 0 2 2 2 0 DBP10CT (NUC160) domain Glyco_hydro_31 PF01055.21 ETO11839.1 - 1.1e-17 63.9 0.3 1.8e-17 63.3 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 ETO11839.1 - 0.00011 21.9 0.1 0.00036 20.3 0.1 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like Glyco_hydro_31 PF01055.21 ETO11840.1 - 1.2e-67 228.6 1.3 1.5e-67 228.3 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 ANTH PF07651.11 ETO11841.1 - 0.08 11.6 1.8 0.095 11.3 0.5 1.7 2 0 0 2 2 2 0 ANTH domain TFIIA PF03153.8 ETO11841.1 - 0.52 10.1 28.6 0.68 9.7 19.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 ETO11841.1 - 1.3 7.2 10.9 1.5 7.0 7.6 1.1 1 0 0 1 1 1 0 Transmembrane protein EpsG PF14897.1 ETO11842.1 - 0.033 13.1 0.4 0.06 12.2 0.3 1.3 1 0 0 1 1 1 0 EpsG family TMEM154 PF15102.1 ETO11842.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family LRR_4 PF12799.2 ETO11843.1 - 2.2e-08 33.5 8.3 8.2e-06 25.3 2.8 2.9 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO11843.1 - 0.00015 21.4 11.7 0.00083 19.0 5.7 3.0 1 1 1 2 2 2 1 Leucine rich repeat LRR_6 PF13516.1 ETO11843.1 - 0.0021 17.9 5.0 4.5 7.6 0.0 4.1 2 2 1 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.28 ETO11843.1 - 0.016 15.1 8.7 6.8 7.1 0.1 4.9 3 2 0 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 ETO11843.1 - 0.017 15.1 6.1 7.7 7.2 0.1 5.0 4 1 0 4 4 4 0 Leucine rich repeat Pollen_allerg_2 PF01620.11 ETO11843.1 - 0.73 10.1 5.4 0.56 10.5 1.9 1.9 1 1 1 2 2 2 0 Ribonuclease (pollen allergen) LRR_4 PF12799.2 ETO11844.1 - 6.3e-23 79.9 46.3 1.2e-07 31.1 4.2 9.3 5 2 6 12 12 12 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO11844.1 - 1.9e-14 53.1 28.8 7.7e-05 22.3 3.7 6.2 2 1 4 7 7 7 6 Leucine rich repeat LRR_1 PF00560.28 ETO11844.1 - 2.4e-10 38.9 59.2 0.52 10.5 0.1 15.9 17 0 0 17 17 17 7 Leucine Rich Repeat LRR_7 PF13504.1 ETO11844.1 - 0.012 15.6 33.5 15 6.3 0.3 12.3 13 0 0 13 13 13 0 Leucine rich repeat VIT1 PF01988.14 ETO11844.1 - 1.1 8.7 4.6 6.3 6.2 0.0 3.9 2 1 1 3 3 3 0 VIT family LRR_6 PF13516.1 ETO11844.1 - 1.6 9.0 38.9 3.4 8.0 0.1 11.5 11 1 1 12 12 12 0 Leucine Rich repeat Ribosomal_L22 PF00237.14 ETO11846.1 - 4.4e-16 58.7 0.1 5.7e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF2663 PF10864.3 ETO11847.1 - 0.025 14.7 2.3 0.031 14.5 1.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) Herpes_TAF50 PF03326.8 ETO11848.1 - 4.7 6.0 12.0 6 5.6 8.3 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) NAP PF00956.13 ETO11851.1 - 0.015 14.4 3.9 0.017 14.2 2.7 1.1 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) DUF2796 PF10986.3 ETO11851.1 - 0.067 13.1 4.0 0.083 12.8 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) TFIIA PF03153.8 ETO11851.1 - 0.12 12.1 10.0 0.13 12.1 6.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2457 PF10446.4 ETO11851.1 - 0.17 10.5 10.9 0.18 10.5 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 ETO11851.1 - 0.37 8.6 14.1 0.41 8.4 9.8 1.0 1 0 0 1 1 1 0 Nop14-like family TLP-20 PF06088.6 ETO11851.1 - 0.81 9.3 8.5 1 8.9 5.9 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CDC45 PF02724.9 ETO11851.1 - 0.84 7.5 8.0 0.8 7.6 5.6 1.1 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.5 ETO11851.1 - 7.2 6.9 17.6 13 6.1 12.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ribosomal_S10 PF00338.17 ETO11852.1 - 0.057 13.2 0.2 0.12 12.2 0.1 1.6 1 1 1 2 2 2 0 Ribosomal protein S10p/S20e DUF4412 PF14371.1 ETO11853.1 - 3 8.4 12.4 3.4 8.2 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4412) RTX_C PF08339.5 ETO11854.1 - 0.011 15.3 0.1 0.019 14.6 0.1 1.3 1 0 0 1 1 1 0 RTX C-terminal domain TnpV PF14198.1 ETO11855.1 - 5.8 6.8 11.4 4.2 7.2 2.4 2.9 3 0 0 3 3 3 0 Transposon-encoded protein TnpV Kelch_6 PF13964.1 ETO11856.1 - 1.7e-05 24.7 0.8 0.02 15.0 0.0 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETO11856.1 - 0.00011 21.8 0.0 0.0011 18.7 0.0 2.7 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO11856.1 - 0.0093 15.9 1.3 0.1 12.5 0.1 3.2 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 ETO11856.1 - 0.023 14.8 0.0 0.12 12.5 0.0 2.3 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO11856.1 - 0.3 10.6 0.1 0.3 10.6 0.1 3.3 4 0 0 4 4 4 0 Kelch motif zf-TRAF PF02176.13 ETO11857.1 - 0.00015 22.0 5.0 0.00015 22.0 3.5 2.4 1 1 0 2 2 2 1 TRAF-type zinc finger DUF3521 PF12035.3 ETO11857.1 - 0.17 11.7 0.2 0.32 10.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3521) WD40 PF00400.27 ETO11858.1 - 5.8e-40 133.7 10.2 4.8e-12 45.2 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO11858.1 - 5.3e-07 29.5 1.5 3.2e-06 27.0 0.2 2.9 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.20 ETO11858.1 - 1.2e-06 27.9 2.0 5e-06 25.9 0.5 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.1 ETO11858.1 - 3.7e-06 26.6 0.1 1.8e-05 24.4 0.1 2.2 1 0 0 1 1 1 1 Galactose oxidase, central domain Nup160 PF11715.3 ETO11858.1 - 9e-05 20.7 1.6 0.25 9.4 0.0 4.1 2 1 2 4 4 4 1 Nucleoporin Nup120/160 Kelch_3 PF13415.1 ETO11858.1 - 9.7e-05 22.4 0.0 0.00036 20.6 0.0 2.0 2 0 0 2 2 2 1 Galactose oxidase, central domain Nbas_N PF15492.1 ETO11858.1 - 0.0049 16.0 0.3 5.5 6.0 0.0 3.5 1 1 3 4 4 4 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 ETO11858.1 - 0.0066 16.0 2.0 21 4.9 0.1 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Kelch_5 PF13854.1 ETO11858.1 - 0.051 13.5 2.6 0.19 11.7 1.0 2.6 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.10 ETO11858.1 - 0.099 12.4 0.9 0.9 9.4 0.1 3.2 3 0 0 3 3 3 0 Kelch motif Iron_permease PF04120.7 ETO11858.1 - 0.23 11.0 3.0 0.7 9.4 0.4 2.2 2 0 0 2 2 2 0 Low affinity iron permease Fez1 PF06818.10 ETO11859.1 - 0.0096 15.9 13.6 0.017 15.1 9.4 1.3 1 0 0 1 1 1 1 Fez1 TFR_dimer PF04253.10 ETO11859.1 - 0.2 11.2 0.1 0.2 11.2 0.1 2.1 3 0 0 3 3 3 0 Transferrin receptor-like dimerisation domain V_ATPase_I PF01496.14 ETO11859.1 - 0.67 7.7 3.5 0.88 7.3 2.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4094 PF13334.1 ETO11859.1 - 0.72 10.2 5.8 0.38 11.1 1.6 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) APG6 PF04111.7 ETO11859.1 - 3 6.8 10.5 5.9 5.8 7.3 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3439 PF11921.3 ETO11860.1 - 0.005 16.5 10.9 0.005 16.5 7.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) Mucin PF01456.12 ETO11860.1 - 0.3 10.8 34.9 0.25 11.0 9.5 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein Tropomodulin PF03250.9 ETO11861.1 - 0.049 13.1 0.1 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 Tropomodulin WD40 PF00400.27 ETO11862.1 - 1.6e-41 138.7 16.2 3.4e-11 42.5 0.0 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO11862.1 - 1.1e-09 37.0 1.1 0.004 15.3 0.0 3.1 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO11862.1 - 0.0093 14.7 9.9 0.76 8.4 0.4 3.7 1 1 3 4 4 4 3 Nup133 N terminal like DUF4221 PF13970.1 ETO11862.1 - 0.012 14.9 0.4 0.072 12.4 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4221) SLD3 PF08639.5 ETO11865.1 - 0.00041 19.1 8.2 0.00047 18.9 5.7 1.0 1 0 0 1 1 1 1 DNA replication regulator SLD3 DUF3353 PF11833.3 ETO11865.1 - 0.15 11.5 1.2 0.22 10.9 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) DUF3513 PF12026.3 ETO11865.1 - 0.2 11.1 4.4 0.24 10.9 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) CDC45 PF02724.9 ETO11865.1 - 0.43 8.5 4.7 0.39 8.7 3.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2956 PF11169.3 ETO11865.1 - 1.4 8.9 22.3 2.5 8.1 15.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) GAGA_bind PF06217.7 ETO11865.1 - 2.6 7.9 12.9 3.2 7.6 9.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family PIP5K PF01504.13 ETO11867.1 - 6.2e-52 176.1 0.6 1.3e-51 175.1 0.4 1.4 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Synaptobrevin PF00957.16 ETO11867.1 - 0.82 9.3 6.9 3.2 7.4 0.6 2.5 2 0 0 2 2 2 0 Synaptobrevin DUF3753 PF12575.3 ETO11867.1 - 6.1 6.7 12.2 2 8.2 1.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) Dehydrin PF00257.14 ETO11868.1 - 0.00028 21.2 3.2 0.00028 21.2 2.2 1.2 1 0 0 1 1 1 1 Dehydrin NACHT PF05729.7 ETO11869.1 - 3.7e-11 42.9 0.0 8.4e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETO11869.1 - 1.4e-05 25.2 0.1 8e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETO11869.1 - 0.00014 22.1 0.1 0.00014 22.1 0.1 3.2 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 ETO11869.1 - 0.00042 21.1 1.1 0.0044 17.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain RelA_SpoT PF04607.12 ETO11869.1 - 0.0014 18.6 0.3 0.0014 18.6 0.2 2.7 4 0 0 4 4 4 1 Region found in RelA / SpoT proteins ATP_bind_2 PF03668.10 ETO11869.1 - 0.016 14.3 0.1 0.049 12.7 0.0 1.8 2 0 0 2 2 2 0 P-loop ATPase protein family AAA_16 PF13191.1 ETO11869.1 - 0.016 15.1 0.3 0.32 10.9 0.1 3.0 2 1 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 ETO11869.1 - 0.038 14.2 0.5 0.19 11.9 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.1 ETO11869.1 - 0.093 12.6 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 ETO11869.1 - 0.27 10.3 7.4 0.55 9.2 0.0 3.6 4 0 0 4 4 4 0 KaiC AKAP_110 PF05716.8 ETO11871.1 - 0.22 9.4 10.7 0.26 9.2 7.4 1.0 1 0 0 1 1 1 0 A-kinase anchor protein 110 kDa (AKAP 110) Srg PF02118.16 ETO11874.1 - 0.37 10.1 4.8 0.52 9.7 3.3 1.2 1 0 0 1 1 1 0 Srg family chemoreceptor RNase_Zc3h12a PF11977.3 ETO11877.1 - 0.0027 17.5 1.0 0.75 9.6 0.0 2.5 2 1 0 2 2 2 2 Zc3h12a-like Ribonuclease NYN domain tRNA-synt_1_2 PF13603.1 ETO11877.1 - 0.03 13.6 0.0 0.067 12.4 0.0 1.6 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 WD40 PF00400.27 ETO11878.1 - 2e-34 116.1 15.3 5.7e-09 35.5 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat HEAT_2 PF13646.1 ETO11880.1 - 7.9e-36 122.2 0.0 5.9e-11 42.5 0.0 8.1 3 1 5 9 9 9 4 HEAT repeats HEAT PF02985.17 ETO11880.1 - 4.4e-31 104.1 0.0 7.9e-05 22.4 0.0 10.1 11 0 0 11 11 11 6 HEAT repeat HEAT_EZ PF13513.1 ETO11880.1 - 1.3e-18 66.9 0.0 2.6e-06 27.7 0.0 8.1 6 3 4 10 10 9 3 HEAT-like repeat Cnd1 PF12717.2 ETO11880.1 - 5.2e-10 39.4 37.8 0.00018 21.4 0.2 6.8 2 2 5 7 7 7 4 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 ETO11880.1 - 1.3e-08 35.1 23.2 0.015 15.6 0.0 8.0 5 3 5 10 10 10 4 Vacuolar 14 Fab1-binding region DUF2435 PF10363.4 ETO11880.1 - 2.6e-08 33.6 18.3 0.34 10.8 0.1 8.4 6 1 2 9 9 9 2 Protein of unknown function (DUF2435) HEAT_PBS PF03130.11 ETO11880.1 - 3.5e-05 23.8 0.1 2.6 8.7 0.0 6.9 10 0 0 10 10 7 1 PBS lyase HEAT-like repeat DUF3554 PF12074.3 ETO11880.1 - 4.1e-05 23.1 15.3 0.059 12.7 0.1 5.8 3 1 2 7 7 7 2 Domain of unknown function (DUF3554) NLE PF08154.7 ETO11880.1 - 0.00033 20.6 15.5 2 8.4 0.0 7.5 10 0 0 10 10 9 1 NLE (NUC135) domain DUF3596 PF12167.3 ETO11880.1 - 0.0042 16.6 0.4 5.5 6.6 0.0 5.3 6 0 0 6 6 6 1 Domain of unknown function (DUF3596) Lumazine_bd_2 PF12893.2 ETO11880.1 - 0.0052 17.3 0.8 12 6.4 0.0 4.8 4 1 0 4 4 4 0 Putative lumazine-binding UME PF08064.8 ETO11880.1 - 0.0096 15.8 13.1 0.57 10.1 0.0 5.9 7 3 1 8 8 7 2 UME (NUC010) domain RNA_binding PF01877.12 ETO11880.1 - 0.014 15.4 22.4 5.8 6.9 0.5 8.3 5 3 4 10 10 10 0 RNA binding DUF2608 PF11019.3 ETO11880.1 - 0.019 13.9 20.1 1 8.2 0.1 6.5 5 3 3 8 8 8 0 Protein of unknown function (DUF2608) TerB-C PF15615.1 ETO11880.1 - 0.037 14.2 10.5 0.87 9.8 0.4 4.6 2 1 4 6 6 6 0 TerB-C domain CheX PF13690.1 ETO11880.1 - 0.1 12.4 1.0 8.2 6.3 0.1 3.3 3 0 0 3 3 3 0 Chemotaxis phosphatase CheX Rsm1 PF08600.5 ETO11880.1 - 0.13 12.1 0.7 29 4.6 0.0 3.3 3 0 0 3 3 3 0 Rsm1-like RecX PF02631.11 ETO11880.1 - 0.2 11.8 2.8 5.3 7.2 0.2 4.0 3 1 1 4 4 4 0 RecX family XkdW PF09636.5 ETO11880.1 - 2.2 8.2 13.9 19 5.2 0.1 5.8 3 2 4 7 7 7 0 XkdW protein IPK PF03770.11 ETO11880.1 - 3.6 7.1 15.2 0.06 12.9 2.4 3.5 2 2 0 3 3 3 0 Inositol polyphosphate kinase Kelch_6 PF13964.1 ETO11881.1 - 2.3e-08 33.8 3.8 2.3 8.5 0.0 5.3 4 1 1 5 5 5 4 Kelch motif Kelch_4 PF13418.1 ETO11881.1 - 3e-07 30.0 3.1 0.2 11.4 0.0 4.9 4 1 1 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO11881.1 - 1.3e-05 24.6 5.4 0.3 10.6 0.0 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 ETO11881.1 - 0.00015 21.8 0.1 2.9 8.1 0.0 4.2 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO11881.1 - 0.013 15.2 4.2 0.81 9.5 0.0 4.4 5 0 0 5 5 5 0 Kelch motif Ank_2 PF12796.2 ETO11882.1 - 0.00013 22.2 0.4 0.034 14.4 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) DUF3661 PF12400.3 ETO11883.1 - 0.091 12.8 0.5 0.13 12.3 0.3 1.3 1 0 0 1 1 1 0 Vaculolar membrane protein Stm1_N PF09598.5 ETO11883.1 - 5.4 7.7 9.9 0.47 11.2 2.6 2.2 2 0 0 2 2 2 0 Stm1 Brix PF04427.13 ETO11884.1 - 3.5e-44 150.7 1.9 4.3e-44 150.4 1.4 1.1 1 0 0 1 1 1 1 Brix domain Kelch_5 PF13854.1 ETO11885.1 - 3.6e-05 23.5 1.4 0.9 9.5 0.1 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO11885.1 - 0.00014 21.5 1.2 0.31 10.8 0.1 4.7 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO11885.1 - 0.00053 20.0 5.6 11 6.3 0.0 5.6 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO11885.1 - 3.2 7.3 10.9 13 5.4 0.0 4.8 6 0 0 6 6 6 0 Kelch motif 7tm_3 PF00003.17 ETO11886.1 - 2.7e-27 95.6 24.2 3.6e-27 95.2 16.8 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Phage_tail_S PF05069.8 ETO11886.1 - 0.23 11.2 0.0 0.4 10.4 0.0 1.3 1 0 0 1 1 1 0 Phage virion morphogenesis family Chlam_PMP PF02415.12 ETO11886.1 - 1.3 9.4 15.2 13 6.2 0.4 5.3 5 0 0 5 5 5 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat C2 PF00168.25 ETO11887.1 - 1.1e-38 130.9 4.3 9.5e-20 70.2 0.1 2.6 2 0 0 2 2 2 2 C2 domain DUF2404 PF10296.4 ETO11887.1 - 0.0014 18.6 0.0 0.0052 16.8 0.0 2.0 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) DUF4550 PF15084.1 ETO11887.1 - 0.0072 16.4 0.9 2.7 8.1 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4550) B56 PF01603.15 ETO11888.1 - 3.5e-34 118.1 5.9 8.1e-21 74.1 0.3 2.1 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) Pyr_redox_3 PF13738.1 ETO11888.1 - 0.063 13.3 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase B56 PF01603.15 ETO11889.1 - 1.1e-20 73.6 0.6 1.7e-20 73.0 0.4 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) CAP_GLY PF01302.20 ETO11889.1 - 7.1e-06 25.6 0.4 1.6e-05 24.4 0.2 1.6 1 0 0 1 1 1 1 CAP-Gly domain WD40 PF00400.27 ETO11890.1 - 3.3e-23 80.6 8.3 4.8e-11 42.0 0.6 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO11890.1 - 0.00012 20.3 0.9 0.00047 18.4 0.6 1.8 1 1 0 1 1 1 1 Nucleoporin Nup120/160 TetM_leader PF08076.6 ETO11890.1 - 0.36 10.4 5.5 1.7 8.2 0.6 3.2 3 0 0 3 3 3 0 Tetracycline resistance determinant leader peptide Ribonuc_L-PSP PF01042.16 ETO11892.1 - 1.1e-22 80.0 0.1 1.5e-22 79.6 0.1 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF1170 PF06663.8 ETO11893.1 - 0.16 11.8 0.4 0.19 11.6 0.2 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1170) DUF3671 PF12420.3 ETO11895.1 - 0.033 14.1 3.0 0.033 14.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function HSP70 PF00012.15 ETO11896.1 - 3.7e-56 190.2 0.0 1.4e-18 66.1 0.0 4.0 4 0 0 4 4 4 4 Hsp70 protein MreB_Mbl PF06723.8 ETO11896.1 - 0.00039 19.1 0.0 0.41 9.1 0.0 3.6 3 2 1 4 4 4 2 MreB/Mbl protein Peptidase_S28 PF05577.7 ETO11898.1 - 0.0022 16.6 0.1 0.018 13.6 0.0 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.6 ETO11898.1 - 0.01 14.3 0.0 0.013 13.9 0.0 1.0 1 0 0 1 1 1 0 PS-10 peptidase S37 TPR_11 PF13414.1 ETO11899.1 - 3.7e-19 68.1 5.2 1.3e-10 40.7 0.8 2.3 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 ETO11899.1 - 1.5e-18 65.1 0.4 4.9e-07 29.1 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO11899.1 - 3.9e-15 54.7 1.0 3.8e-08 32.5 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 ETO11899.1 - 3.5e-10 39.6 0.6 3.3e-06 26.9 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO11899.1 - 2e-09 37.8 0.0 6.3e-06 26.7 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO11899.1 - 3.6e-07 29.9 2.2 0.0018 18.1 0.1 3.2 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.1 ETO11899.1 - 1.5e-06 27.5 2.0 7.4e-05 22.2 0.0 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat FKBP_C PF00254.23 ETO11899.1 - 8.8e-06 25.6 0.2 6e-05 22.9 0.0 2.5 3 1 0 3 3 3 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_6 PF13174.1 ETO11899.1 - 1.8e-05 24.9 0.2 0.06 13.8 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETO11899.1 - 3.5e-05 23.5 0.1 0.044 13.7 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO11899.1 - 5.9e-05 23.3 1.0 0.014 15.7 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO11899.1 - 7.3e-05 22.2 0.1 0.031 14.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO11899.1 - 0.00011 22.5 0.0 0.37 11.5 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat DUF3271 PF11675.3 ETO11899.1 - 0.00017 20.7 1.2 0.00026 20.2 0.5 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3271) TPR_17 PF13431.1 ETO11899.1 - 0.00055 19.9 2.5 5.6 7.4 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO11899.1 - 0.00098 19.2 2.6 0.028 14.5 1.8 2.6 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 ETO11899.1 - 0.02 14.7 0.0 0.58 10.0 0.0 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.1 ETO11899.1 - 0.071 13.2 2.1 13 5.9 0.1 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat Curto_V2 PF07325.6 ETO11899.1 - 0.14 11.7 1.6 0.15 11.7 0.4 1.6 2 0 0 2 2 2 0 Curtovirus V2 protein FKBP_C PF00254.23 ETO11900.1 - 1.4e-21 76.3 0.0 2.4e-12 46.7 0.0 3.0 3 0 0 3 3 3 2 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4500 PF14937.1 ETO11900.1 - 0.056 13.2 0.2 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) Baculo_11_kDa PF06143.6 ETO11900.1 - 0.1 11.9 1.3 0.68 9.3 0.2 2.2 2 0 0 2 2 2 0 Baculovirus 11 kDa family EphA2_TM PF14575.1 ETO11900.1 - 0.36 11.2 3.3 0.72 10.2 0.1 2.6 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF2762 PF10960.3 ETO11900.1 - 3.3 7.5 5.8 1.1 8.9 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2762) TPR_11 PF13414.1 ETO11901.1 - 0.0012 18.3 0.6 0.0028 17.2 0.4 1.6 1 0 0 1 1 1 1 TPR repeat DUF2101 PF09874.4 ETO11901.1 - 0.019 14.4 1.2 0.03 13.7 0.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) Pex14_N PF04695.8 ETO11901.1 - 0.42 10.6 7.2 0.038 14.0 1.7 1.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mucin PF01456.12 ETO11901.1 - 0.85 9.3 17.9 0.023 14.4 7.9 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3439 PF11921.3 ETO11901.1 - 1.4 8.6 9.4 0.4 10.4 3.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 ETO11901.1 - 2.5 5.9 23.7 0.82 7.5 14.0 1.7 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Paramyxo_C PF01692.13 ETO11901.1 - 8.5 5.9 6.3 18 4.8 4.4 1.4 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c DUF791 PF05631.9 ETO11902.1 - 1.1e-66 224.9 20.5 2e-32 112.2 4.2 3.6 3 1 1 4 4 4 3 Protein of unknown function (DUF791) MFS_1 PF07690.11 ETO11902.1 - 1.1e-06 27.6 33.3 0.00039 19.2 17.6 4.2 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF2631 PF10939.3 ETO11902.1 - 0.017 14.9 0.8 16 5.4 0.0 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2631) KilA-N PF04383.8 ETO11902.1 - 0.09 12.4 0.1 0.23 11.0 0.1 1.6 1 0 0 1 1 1 0 KilA-N domain Cytochrom_B561 PF03188.11 ETO11903.1 - 1.2e-09 38.1 5.3 1.2e-09 38.1 3.7 2.3 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 DOMON PF03351.12 ETO11903.1 - 0.002 18.0 2.2 0.021 14.7 0.1 2.7 2 1 0 2 2 2 1 DOMON domain DUF3382 PF11862.3 ETO11903.1 - 0.0046 16.8 1.4 0.012 15.4 1.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3382) TauE PF01925.14 ETO11903.1 - 0.0052 16.2 10.7 0.0085 15.5 7.4 1.2 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE DUF2231 PF09990.4 ETO11903.1 - 6.9 7.0 16.1 4 7.8 2.7 3.4 2 1 1 3 3 3 0 Predicted membrane protein (DUF2231) PT PF04886.7 ETO11904.1 - 1.7e-06 27.2 44.7 9.9e-06 24.7 9.8 3.3 1 1 2 3 3 3 3 PT repeat FAP PF07174.6 ETO11904.1 - 0.58 9.4 14.3 1.1 8.4 9.9 1.4 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Pneumo_att_G PF05539.6 ETO11904.1 - 1.3 8.3 7.0 2.7 7.2 4.9 1.5 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DOMON PF03351.12 ETO11905.1 - 0.00042 20.2 0.3 0.0012 18.7 0.0 1.9 2 0 0 2 2 2 1 DOMON domain NUDIX PF00293.23 ETO11906.1 - 3e-11 43.1 0.0 7.6e-11 41.7 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain zf-Di19 PF05605.7 ETO11906.1 - 0.017 15.2 0.9 0.017 15.2 0.6 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding AFG1_ATPase PF03969.11 ETO11907.1 - 9.2e-73 245.1 7.8 5.7e-68 229.3 2.6 3.9 1 1 0 2 2 2 2 AFG1-like ATPase UvrD-helicase PF00580.16 ETO11907.1 - 0.0011 18.2 2.6 0.5 9.6 0.7 3.1 2 1 0 2 2 2 2 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 ETO11907.1 - 0.011 15.8 0.0 0.063 13.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 ETO11907.1 - 0.03 14.6 0.0 0.03 14.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Adenyl_cycl_N PF12633.2 ETO11907.1 - 0.061 12.8 0.0 0.21 11.0 0.0 1.9 2 1 0 2 2 2 0 Adenylate cyclase NT domain Sigma54_activ_2 PF14532.1 ETO11907.1 - 0.075 13.0 0.0 2.7 8.0 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain WD40 PF00400.27 ETO11908.1 - 2.5e-27 93.7 13.6 1.6e-05 24.6 0.3 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat MyTH4 PF00784.12 ETO11910.1 - 0.018 14.9 0.9 0.054 13.4 0.3 2.1 2 0 0 2 2 2 0 MyTH4 domain NGP1NT PF08153.7 ETO11910.1 - 0.12 12.3 3.4 8.8 6.2 0.0 2.7 3 0 0 3 3 3 0 NGP1NT (NUC091) domain SAM_1 PF00536.25 ETO11911.1 - 2.2e-09 37.3 0.8 6.2e-09 35.8 0.6 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO11911.1 - 1.1e-06 28.3 0.4 2.8e-06 27.0 0.3 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF310 PF03750.8 ETO11911.1 - 0.026 14.7 0.4 0.026 14.7 0.3 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF310) ZZ PF00569.12 ETO11912.1 - 2.2e-14 52.6 5.0 3.7e-14 52.0 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type UBA PF00627.26 ETO11913.1 - 0.00028 20.6 0.0 0.0031 17.3 0.0 2.6 2 0 0 2 2 2 1 UBA/TS-N domain ZZ PF00569.12 ETO11913.1 - 0.8 9.2 4.8 2.5 7.7 3.4 1.8 1 1 0 1 1 1 0 Zinc finger, ZZ type CTP_transf_2 PF01467.21 ETO11914.1 - 1.9e-14 54.0 0.0 3.7e-14 53.0 0.0 1.5 1 1 0 1 1 1 1 Cytidylyltransferase RIO1 PF01163.17 ETO11915.1 - 0.023 14.0 0.0 0.075 12.3 0.0 1.8 1 1 1 2 2 2 0 RIO1 family vWA-TerF-like PF10138.4 ETO11915.1 - 0.043 13.6 0.1 0.12 12.1 0.0 1.7 2 1 0 2 2 2 0 vWA found in TerF C terminus WD40 PF00400.27 ETO11916.1 - 4.2e-26 89.8 5.7 2.4e-12 46.2 0.0 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO11916.1 - 1.2e-08 33.6 1.2 0.00062 18.0 0.6 2.7 1 1 1 2 2 2 2 Nucleoporin Nup120/160 MetW PF07021.7 ETO11916.1 - 0.052 12.9 0.1 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Apc3 PF12895.2 ETO11917.1 - 0.014 15.4 0.9 3.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 EnY2 PF10163.4 ETO11918.1 - 4.5e-28 97.0 0.4 5.7e-28 96.6 0.3 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 Bacillus_HBL PF05791.6 ETO11919.1 - 0.0097 15.2 8.6 0.015 14.7 6.0 1.3 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) DUF310 PF03750.8 ETO11919.1 - 0.051 13.7 5.5 0.095 12.8 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF310) Mer2 PF09074.5 ETO11919.1 - 0.074 12.9 8.6 0.015 15.2 2.8 2.0 2 0 0 2 2 2 0 Mer2 DUF1423 PF07227.6 ETO11919.1 - 0.088 11.4 16.8 0.1 11.2 11.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) bZIP_1 PF00170.16 ETO11919.1 - 0.098 12.6 12.3 0.14 12.1 5.2 2.8 1 1 1 2 2 2 0 bZIP transcription factor NAAA-beta PF15508.1 ETO11919.1 - 0.13 12.6 2.3 0.9 9.9 1.3 2.3 1 1 1 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF836 PF05768.9 ETO11919.1 - 0.17 12.1 5.0 0.83 9.9 3.5 2.0 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DUF763 PF05559.6 ETO11919.1 - 0.23 10.4 4.5 0.28 10.1 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Dynactin_p62 PF05502.8 ETO11919.1 - 0.27 9.9 7.1 0.31 9.7 4.9 1.1 1 0 0 1 1 1 0 Dynactin p62 family DUF3713 PF12506.3 ETO11919.1 - 0.3 11.1 3.5 1.6 8.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) DUF2779 PF11074.3 ETO11919.1 - 0.34 10.9 5.9 0.61 10.1 4.1 1.5 1 1 0 1 1 1 0 Domain of unknown function(DUF2779) IFT20 PF14931.1 ETO11919.1 - 0.48 10.3 14.6 0.31 10.9 4.0 2.7 1 1 1 3 3 3 0 Intraflagellar transport complex B, subunit 20 UvsW PF11637.3 ETO11919.1 - 0.58 9.8 6.5 3.8 7.2 0.0 2.6 2 0 0 2 2 2 0 ATP-dependant DNA helicase UvsW Tho2 PF11262.3 ETO11919.1 - 0.59 9.1 9.3 0.51 9.3 5.8 1.4 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF507 PF04368.8 ETO11919.1 - 0.64 9.6 13.0 0.48 10.0 7.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF507) Ax_dynein_light PF10211.4 ETO11919.1 - 1 9.1 16.6 0.67 9.7 5.8 2.4 1 1 1 2 2 2 0 Axonemal dynein light chain Seryl_tRNA_N PF02403.17 ETO11919.1 - 1.6 8.7 14.8 2.2 8.3 5.4 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 ETO11919.1 - 2.6 6.9 17.5 3.3 6.6 12.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DALR_1 PF05746.10 ETO11919.1 - 2.7 7.9 8.7 6.6 6.7 5.7 1.9 1 1 1 2 2 2 0 DALR anticodon binding domain Shugoshin_N PF07558.6 ETO11919.1 - 3.2 7.5 7.1 1.6 8.4 2.2 2.5 2 1 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Exonuc_VII_L PF02601.10 ETO11919.1 - 3.3 6.8 11.7 4.2 6.4 8.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit ACCA PF03255.9 ETO11919.1 - 5 6.6 10.1 1.2 8.6 2.0 2.2 1 1 3 4 4 4 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit CorA PF01544.13 ETO11919.1 - 6.8 5.6 8.5 9 5.2 5.8 1.3 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein eIF-4B PF06273.6 ETO11919.1 - 8.1 5.0 8.8 9.5 4.8 6.0 1.3 1 1 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B ABC_membrane PF00664.18 ETO11920.1 - 4.9e-13 49.1 15.5 4.1e-09 36.2 4.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 ETO11920.1 - 1.7e-06 28.3 2.2 1.9e-06 28.2 0.4 1.9 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 ETO11920.1 - 0.0026 17.2 0.1 0.0062 16.0 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ArgK PF03308.11 ETO11920.1 - 0.0051 15.6 0.0 0.0094 14.7 0.0 1.3 1 0 0 1 1 1 1 ArgK protein ATP_bind_1 PF03029.12 ETO11920.1 - 0.0096 15.4 0.4 0.79 9.2 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 ETO11920.1 - 0.033 13.9 2.8 0.037 13.8 0.8 1.9 2 0 0 2 2 2 0 Dynamin family GTP_EFTU PF00009.22 ETO11920.1 - 0.048 13.0 0.2 0.23 10.8 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_21 PF13304.1 ETO11920.1 - 0.057 13.3 0.7 0.12 12.2 0.5 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 ETO11920.1 - 0.076 12.4 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family cobW PF02492.14 ETO11920.1 - 0.076 12.4 1.0 0.14 11.5 0.2 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 ETO11920.1 - 0.14 11.5 1.0 0.53 9.6 0.2 2.3 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 ETO11920.1 - 0.16 11.9 1.3 0.33 10.9 0.3 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.1 ETO11920.1 - 0.19 11.6 0.4 0.42 10.5 0.3 1.5 1 0 0 1 1 1 0 AAA ATPase domain IncA PF04156.9 ETO11921.1 - 0.0018 17.8 10.3 0.0018 17.8 7.2 4.2 4 1 1 5 5 5 1 IncA protein TPR_12 PF13424.1 ETO11922.1 - 2e-67 223.1 16.1 6.8e-16 57.9 0.8 5.8 2 2 3 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETO11922.1 - 8e-39 129.6 30.0 3e-06 26.6 1.0 8.5 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_11 PF13414.1 ETO11922.1 - 9.1e-34 114.9 21.9 6.7e-09 35.2 0.1 5.5 4 1 1 5 5 5 5 TPR repeat TPR_2 PF07719.12 ETO11922.1 - 5.4e-31 104.0 22.3 0.00011 21.8 0.5 8.7 9 0 0 9 9 8 8 Tetratricopeptide repeat TPR_10 PF13374.1 ETO11922.1 - 1.3e-25 88.5 0.0 0.00044 20.0 0.0 7.8 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.1 ETO11922.1 - 3.3e-23 79.6 6.3 0.012 15.3 0.1 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETO11922.1 - 2e-22 77.2 45.1 0.00023 20.6 0.4 9.2 9 1 0 9 9 9 7 Tetratricopeptide repeat TPR_14 PF13428.1 ETO11922.1 - 1.2e-12 47.2 0.0 0.19 12.4 0.0 7.7 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO11922.1 - 4.5e-09 36.7 0.0 0.48 11.1 0.0 5.5 5 2 2 7 7 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO11922.1 - 5.1e-09 35.9 11.5 8.2 7.1 0.0 8.6 9 1 1 10 10 9 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO11922.1 - 9.2e-08 31.7 19.6 2.6 8.4 0.1 8.8 8 1 0 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 ETO11922.1 - 1.6e-07 31.3 27.2 0.0043 17.1 4.6 5.3 1 1 5 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 Foie-gras_1 PF11817.3 ETO11922.1 - 0.00084 18.8 3.4 0.35 10.3 0.3 2.6 1 1 1 2 2 2 2 Foie gras liver health family 1 SHNi-TPR PF10516.4 ETO11922.1 - 0.0013 17.9 5.9 8.1 5.7 0.1 6.1 7 0 0 7 7 7 1 SHNi-TPR TPR_3 PF07720.7 ETO11922.1 - 0.004 16.9 9.5 0.3 10.9 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat Prefoldin PF02996.12 ETO11922.1 - 0.014 15.0 3.3 0.084 12.5 0.1 3.8 3 1 2 5 5 5 0 Prefoldin subunit TPR_19 PF14559.1 ETO11922.1 - 0.029 14.6 3.9 2.8 8.3 0.0 4.5 4 2 2 6 6 5 0 Tetratricopeptide repeat PPR PF01535.15 ETO11922.1 - 0.74 9.9 3.3 18 5.6 0.0 4.7 6 0 0 6 6 6 0 PPR repeat WD40 PF00400.27 ETO11923.1 - 1.7e-45 151.3 11.1 4.5e-11 42.1 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO11923.1 - 5.7e-08 31.3 1.6 0.18 9.8 0.2 4.0 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO11923.1 - 0.00067 18.5 5.8 0.052 12.2 1.0 3.1 1 1 2 3 3 3 2 Nup133 N terminal like SprB PF13573.1 ETO11923.1 - 0.0052 16.3 1.9 0.82 9.3 0.4 3.5 3 0 0 3 3 3 1 SprB repeat Arena_nucleocap PF00843.12 ETO11923.1 - 0.028 12.3 0.7 2.5 5.8 0.0 3.3 2 1 2 4 4 4 0 Arenavirus nucleocapsid protein eIF2A PF08662.6 ETO11923.1 - 0.047 13.4 1.3 4.9 6.8 0.0 3.0 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A EzrA PF06160.7 ETO11925.1 - 0.004 15.4 9.7 0.035 12.2 3.0 2.0 2 0 0 2 2 2 2 Septation ring formation regulator, EzrA Tropomyosin_1 PF12718.2 ETO11925.1 - 0.004 16.9 9.0 0.004 16.9 6.2 2.2 2 0 0 2 2 2 1 Tropomyosin like FlxA PF14282.1 ETO11925.1 - 0.062 13.2 9.9 0.46 10.4 3.7 2.5 2 1 0 2 2 2 0 FlxA-like protein NPV_P10 PF05531.7 ETO11925.1 - 0.087 13.0 1.3 9.2 6.5 0.8 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Erp_C PF06780.6 ETO11925.1 - 0.19 11.5 10.2 0.22 11.3 5.5 2.1 2 1 0 2 2 2 0 Erp protein C-terminus DUF724 PF05266.9 ETO11925.1 - 0.23 11.0 9.5 0.15 11.7 4.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Vfa1 PF08432.5 ETO11925.1 - 0.46 10.5 8.5 2.8 7.9 3.8 2.4 1 1 1 2 2 2 0 AAA-ATPase Vps4-associated protein 1 APG6 PF04111.7 ETO11925.1 - 0.55 9.2 13.9 0.068 12.2 5.6 1.9 2 0 0 2 2 2 0 Autophagy protein Apg6 Cortex-I_coil PF09304.5 ETO11925.1 - 0.8 9.7 13.0 0.19 11.7 5.8 2.1 2 1 0 2 2 2 0 Cortexillin I, coiled coil Myosin_tail_1 PF01576.14 ETO11925.1 - 0.82 7.3 13.8 0.12 10.1 6.7 1.6 2 0 0 2 2 2 0 Myosin tail THOC7 PF05615.8 ETO11925.1 - 1.5 9.0 11.8 0.11 12.7 4.4 1.9 2 0 0 2 2 2 0 Tho complex subunit 7 Syntaxin-6_N PF09177.6 ETO11925.1 - 1.6 9.2 6.6 17 5.8 0.0 2.9 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Microtub_assoc PF07989.6 ETO11925.1 - 1.7 8.5 14.1 0.21 11.4 1.4 2.9 2 1 1 3 3 3 0 Microtubule associated Spc7 PF08317.6 ETO11925.1 - 2.3 6.7 15.0 0.4 9.2 7.2 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein BCAS2 PF05700.6 ETO11925.1 - 2.5 7.5 12.9 0.7 9.3 6.4 2.1 1 1 1 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) ATG16 PF08614.6 ETO11925.1 - 2.7 7.7 14.8 0.21 11.3 6.9 1.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Laminin_II PF06009.7 ETO11925.1 - 4 7.2 9.1 13 5.5 3.9 2.4 2 0 0 2 2 2 0 Laminin Domain II IncA PF04156.9 ETO11925.1 - 4.9 6.7 10.4 0.49 9.9 3.5 1.9 2 0 0 2 2 2 0 IncA protein DUF4337 PF14235.1 ETO11925.1 - 6.8 6.4 7.2 1.4 8.7 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Nup54 PF13874.1 ETO11925.1 - 7.9 6.1 9.2 1.7 8.3 1.3 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 LigB PF02900.13 ETO11926.1 - 7.2e-20 71.0 0.0 9.3e-20 70.7 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase CSD PF00313.17 ETO11927.1 - 8.8e-11 41.4 3.4 1.8e-05 24.3 0.3 2.8 2 0 0 2 2 2 2 'Cold-shock' DNA-binding domain PAT1 PF09770.4 ETO11927.1 - 0.0022 16.3 22.1 0.0023 16.2 15.3 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 ETO11927.1 - 0.019 14.3 19.2 0.022 14.1 13.3 1.1 1 0 0 1 1 1 0 Vta1 like CDK5_activator PF03261.10 ETO11927.1 - 0.023 14.0 7.9 0.027 13.8 5.5 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF4175 PF13779.1 ETO11927.1 - 0.08 10.6 12.3 0.13 9.9 8.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SAGA-Tad1 PF12767.2 ETO11927.1 - 0.66 9.5 13.7 0.89 9.1 9.5 1.5 1 1 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF4551 PF15087.1 ETO11927.1 - 1.1 7.4 11.2 1.4 7.1 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PHD_3 PF13922.1 ETO11927.1 - 5.2 7.3 11.5 21 5.4 8.0 2.1 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Pneumo_phosprot PF02478.11 ETO11927.1 - 5.5 6.4 8.9 14 5.1 0.1 2.2 2 0 0 2 2 2 0 Pneumovirus phosphoprotein Pex14_N PF04695.8 ETO11927.1 - 8.6 6.4 17.5 1.8 8.6 9.6 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RusA PF05866.6 ETO11929.1 - 0.13 12.6 1.9 0.19 12.1 1.3 1.2 1 0 0 1 1 1 0 Endodeoxyribonuclease RusA LIN37 PF15306.1 ETO11929.1 - 0.52 10.2 5.8 0.2 11.6 2.5 1.5 2 0 0 2 2 2 0 LIN37 Peptidase_M28 PF04389.12 ETO11930.1 - 8e-06 25.7 0.0 1.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 CENP-T PF15511.1 ETO11930.1 - 0.0022 17.3 5.1 0.0024 17.1 3.5 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CDC45 PF02724.9 ETO11930.1 - 0.053 11.5 12.0 0.069 11.1 8.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 ETO11930.1 - 0.15 11.4 14.0 0.3 10.4 9.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Daxx PF03344.10 ETO11930.1 - 2.9 6.2 19.7 3.8 5.8 13.7 1.1 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 ETO11930.1 - 2.9 7.0 24.1 4 6.6 16.7 1.1 1 0 0 1 1 1 0 SDA1 U79_P34 PF03064.11 ETO11930.1 - 3 7.3 18.3 5.8 6.3 12.7 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Miro PF08477.8 ETO11933.1 - 1.6e-05 25.3 0.0 0.0025 18.2 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein RNA_helicase PF00910.17 ETO11933.1 - 0.00023 21.3 0.3 0.029 14.5 0.0 3.0 3 0 0 3 3 3 1 RNA helicase DUF258 PF03193.11 ETO11933.1 - 0.00044 19.4 0.1 0.011 14.9 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 ETO11933.1 - 0.001 19.3 0.0 0.0037 17.5 0.0 2.0 2 0 0 2 2 2 1 ABC transporter Arch_ATPase PF01637.13 ETO11933.1 - 0.0022 17.7 0.6 0.0054 16.4 0.0 2.1 1 1 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 ETO11933.1 - 0.003 17.6 0.1 0.026 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 ETO11933.1 - 0.0032 17.1 0.0 0.0066 16.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain MMR_HSR1 PF01926.18 ETO11933.1 - 0.0036 17.2 0.0 1.8 8.5 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_17 PF13207.1 ETO11933.1 - 0.0038 18.0 0.4 5.9 7.7 0.2 2.9 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.1 ETO11933.1 - 0.0039 17.1 0.1 0.01 15.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain SRP14 PF02290.10 ETO11933.1 - 0.0059 16.5 1.2 0.011 15.5 0.8 1.4 1 0 0 1 1 1 1 Signal recognition particle 14kD protein AAA_15 PF13175.1 ETO11933.1 - 0.0087 15.1 2.1 0.034 13.1 1.5 1.9 1 1 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.13 ETO11933.1 - 0.016 14.7 0.2 0.095 12.2 0.0 2.2 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.9 ETO11933.1 - 0.018 14.7 0.0 0.055 13.1 0.0 1.8 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 ETO11933.1 - 0.04 14.1 0.0 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 ETO11933.1 - 0.076 12.9 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 ETO11933.1 - 0.14 11.1 2.0 4.8 6.1 0.0 2.7 2 1 1 3 3 3 0 Septin SRPRB PF09439.5 ETO11933.1 - 0.19 10.9 2.3 12 5.0 0.0 3.1 2 1 1 3 3 3 0 Signal recognition particle receptor beta subunit AAA_23 PF13476.1 ETO11933.1 - 0.3 11.4 3.2 0.15 12.3 0.2 1.9 1 1 1 2 2 2 0 AAA domain CENP-L PF13092.1 ETO11934.1 - 0.05 13.3 0.1 0.094 12.4 0.1 1.4 1 0 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 RRN3 PF05327.6 ETO11934.1 - 7.1 4.6 15.6 2.5 6.0 8.8 1.6 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 zf-RanBP PF00641.13 ETO11936.1 - 0.0004 19.4 32.4 0.0011 18.0 4.7 3.5 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DUF572 PF04502.8 ETO11936.1 - 1.3 8.1 16.0 0.24 10.5 8.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF572) Zn_Tnp_IS1595 PF12760.2 ETO11936.1 - 7 6.5 18.3 0.93 9.3 0.2 3.8 4 0 0 4 4 4 0 Transposase zinc-ribbon domain RabGAP-TBC PF00566.13 ETO11938.1 - 0.055 12.9 0.0 0.055 12.9 0.0 2.0 2 0 0 2 2 2 0 Rab-GTPase-TBC domain Packaging_FI PF14000.1 ETO11938.1 - 5.9 7.1 11.1 1.8 8.7 2.3 2.4 2 0 0 2 2 2 0 DNA packaging protein FI Guanylate_kin PF00625.16 ETO11939.1 - 2.1e-41 141.3 1.9 6.1e-39 133.3 1.3 2.2 1 1 0 1 1 1 1 Guanylate kinase AAA_17 PF13207.1 ETO11939.1 - 8e-06 26.6 0.3 1.8e-05 25.5 0.0 1.8 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.1 ETO11939.1 - 1.8e-05 25.0 0.2 1.8e-05 25.0 0.1 1.9 2 1 0 2 2 1 1 AAA domain DUF258 PF03193.11 ETO11939.1 - 3.3e-05 23.1 0.0 6.8e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 ETO11939.1 - 3.8e-05 23.8 0.1 0.00025 21.2 0.1 2.1 1 1 0 1 1 1 1 AAA domain Miro PF08477.8 ETO11939.1 - 0.00013 22.3 0.0 0.0004 20.8 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein ABC_tran PF00005.22 ETO11939.1 - 0.00043 20.5 1.2 0.0076 16.5 0.8 2.2 1 1 0 1 1 1 1 ABC transporter AAA_33 PF13671.1 ETO11939.1 - 0.0016 18.2 0.6 0.01 15.7 0.4 2.1 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 ETO11939.1 - 0.0021 18.0 0.1 0.0034 17.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 ETO11939.1 - 0.0024 17.6 0.1 0.0035 17.0 0.1 1.4 1 1 0 1 1 1 1 Archaeal ATPase Rad17 PF03215.10 ETO11939.1 - 0.0028 16.4 0.0 0.0038 15.9 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 ETO11939.1 - 0.011 15.5 0.1 0.024 14.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETO11939.1 - 0.017 15.0 0.1 0.022 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Ras PF00071.17 ETO11939.1 - 0.017 14.4 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Ras family RNA_helicase PF00910.17 ETO11939.1 - 0.022 14.8 0.0 0.13 12.4 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.1 ETO11939.1 - 0.031 14.2 0.1 0.09 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 ETO11939.1 - 0.033 13.8 0.1 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 ETO11939.1 - 0.037 13.1 0.0 0.079 12.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.17 ETO11939.1 - 0.042 12.7 0.2 0.084 11.7 0.1 1.6 1 1 0 1 1 1 0 NB-ARC domain PRK PF00485.13 ETO11939.1 - 0.072 12.6 0.1 0.23 11.0 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.1 ETO11939.1 - 0.095 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Thymidylate_kin PF02223.12 ETO11939.1 - 0.1 11.9 4.6 0.15 11.4 0.0 2.7 2 1 1 3 3 3 0 Thymidylate kinase AAA_24 PF13479.1 ETO11939.1 - 0.11 12.0 0.6 0.24 10.9 0.1 1.8 2 1 0 2 2 2 0 AAA domain DUF4059 PF13268.1 ETO11940.1 - 7 6.9 14.2 6.4 7.0 1.5 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF4059) FAM131 PF15010.1 ETO11941.1 - 0.26 11.0 10.6 0.32 10.6 7.3 1.1 1 0 0 1 1 1 0 Putative cell signalling Peptidase_S64 PF08192.6 ETO11941.1 - 0.61 8.3 11.9 0.67 8.2 8.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 SprA-related PF12118.3 ETO11941.1 - 0.95 8.7 21.0 1.4 8.1 14.6 1.2 1 0 0 1 1 1 0 SprA-related family CDC45 PF02724.9 ETO11941.1 - 0.97 7.3 10.2 1.3 6.9 1.4 2.0 2 0 0 2 2 2 0 CDC45-like protein Pox_Ag35 PF03286.9 ETO11941.1 - 2.7 7.4 16.7 0.6 9.5 2.4 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CPSF100_C PF13299.1 ETO11941.1 - 3.6 7.7 13.4 0.27 11.3 1.4 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF1675 PF07897.6 ETO11941.1 - 5.6 6.7 16.6 7.9 6.2 11.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) RhoGAP PF00620.22 ETO11942.1 - 1.6e-24 86.2 1.1 1.5e-13 50.6 0.0 2.9 3 0 0 3 3 3 2 RhoGAP domain NAC PF01849.13 ETO11943.1 - 0.03 13.8 0.3 0.12 11.9 0.2 2.1 1 0 0 1 1 1 0 NAC domain TipAS PF07739.8 ETO11943.1 - 0.031 14.5 0.0 0.063 13.6 0.0 1.4 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain ORC5_C PF14630.1 ETO11943.1 - 5.4 6.3 7.7 1.7 8.0 3.2 1.6 2 1 0 2 2 2 0 Origin recognition complex (ORC) subunit 5 C-terminus RGS PF00615.14 ETO11945.1 - 3.3e-08 33.6 0.0 6.1e-08 32.7 0.0 1.5 1 1 0 1 1 1 1 Regulator of G protein signaling domain WD40 PF00400.27 ETO11946.1 - 4.4e-47 156.3 12.0 2.9e-11 42.7 0.3 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO11946.1 - 1.8e-06 26.3 1.1 0.53 8.3 0.0 4.0 2 2 1 4 4 4 4 Nucleoporin Nup120/160 TGS PF02824.16 ETO11947.1 - 6.5e-22 77.1 0.0 1.3e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 ETO11947.1 - 6e-17 61.6 0.0 1.8e-16 60.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETO11947.1 - 8.3e-09 34.9 0.0 2e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 ETO11947.1 - 0.00099 19.5 0.0 0.0022 18.4 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 ETO11947.1 - 0.027 14.3 0.3 3.9 7.2 0.1 2.6 1 1 0 2 2 2 0 Dynamin family Glycos_transf_2 PF00535.21 ETO11947.1 - 0.05 13.2 0.2 0.11 12.1 0.2 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 TypeIII_RM_meth PF12564.3 ETO11947.1 - 0.85 9.6 4.8 2.2 8.3 1.3 2.5 2 0 0 2 2 2 0 Type III restriction/modification enzyme methylation subunit Claudin_3 PF06653.6 ETO11948.1 - 0.0046 16.6 0.8 0.0046 16.6 0.5 2.2 2 0 0 2 2 2 1 Tight junction protein, Claudin-like DUF4131 PF13567.1 ETO11948.1 - 0.039 13.3 1.9 0.51 9.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF843 PF05814.6 ETO11948.1 - 1.6 8.5 10.7 2.7 7.8 1.4 2.9 2 1 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) RasGAP PF00616.14 ETO11949.1 - 2.9e-24 85.8 3.3 2.9e-24 85.8 2.3 2.8 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase GCR1_C PF12550.3 ETO11949.1 - 0.022 14.6 0.2 7.5 6.4 0.0 2.6 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes MIP-T3 PF10243.4 ETO11949.1 - 0.031 12.7 25.3 0.045 12.2 17.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CDC45 PF02724.9 ETO11949.1 - 1.4 6.8 23.1 0.87 7.5 5.3 2.2 2 0 0 2 2 2 0 CDC45-like protein AKAP7_NLS PF10469.4 ETO11950.1 - 4.9e-20 72.1 8.7 2e-17 63.5 6.0 3.0 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.1 ETO11950.1 - 0.0004 20.1 0.0 0.00074 19.2 0.0 1.4 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.11 ETO11950.1 - 0.0038 17.1 0.0 3.5 7.6 0.0 2.4 2 0 0 2 2 2 2 LigT like Phosphoesterase Guanylate_kin PF00625.16 ETO11951.1 - 2.7e-22 79.0 2.9 1.8e-12 47.1 0.0 3.7 2 1 1 3 3 3 2 Guanylate kinase AAA_22 PF13401.1 ETO11951.1 - 2.8e-05 24.2 0.5 0.0011 19.1 0.0 2.3 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 ETO11951.1 - 4.4e-05 22.7 0.7 7.5e-05 21.9 0.4 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 ETO11951.1 - 0.0018 18.3 0.2 0.0074 16.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 ETO11951.1 - 0.0037 17.5 0.4 0.022 15.0 0.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETO11951.1 - 0.0053 16.6 4.0 0.016 15.0 0.6 3.0 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 ETO11951.1 - 0.0061 16.2 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 NTPase BCAS3 PF12490.3 ETO11951.1 - 0.0074 15.6 0.1 0.012 14.9 0.1 1.3 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 3 ABC_tran PF00005.22 ETO11951.1 - 0.0096 16.2 1.1 0.077 13.2 0.8 2.2 1 1 0 1 1 1 1 ABC transporter RNA_helicase PF00910.17 ETO11951.1 - 0.011 15.8 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 ETO11951.1 - 0.014 15.1 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 ETO11951.1 - 0.023 15.5 0.3 0.059 14.1 0.2 1.8 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 ETO11951.1 - 0.032 14.7 0.1 0.11 12.9 0.0 1.9 1 1 0 2 2 2 0 Miro-like protein AAA PF00004.24 ETO11951.1 - 0.033 14.4 0.1 0.092 12.9 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 ETO11951.1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Zip PF02535.17 ETO11951.1 - 0.12 11.3 7.5 0.17 10.8 5.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter cobW PF02492.14 ETO11951.1 - 0.13 11.7 0.1 0.33 10.3 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 ETO11951.1 - 0.13 12.1 0.0 0.42 10.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 ETO11951.1 - 0.34 10.5 0.0 0.34 10.5 0.0 2.0 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Tubulin_C PF03953.12 ETO11954.1 - 9.5e-08 32.1 0.0 1.3e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain FAM177 PF14774.1 ETO11955.1 - 2.3e-11 43.7 9.6 7.6e-11 41.9 6.2 2.1 1 1 0 1 1 1 1 FAM177 family UPF0122 PF04297.9 ETO11955.1 - 0.076 13.0 0.8 0.076 13.0 0.6 1.8 2 1 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like EIAV_GP90 PF00971.13 ETO11955.1 - 0.088 11.2 0.9 0.11 10.8 0.7 1.1 1 0 0 1 1 1 0 EIAV coat protein, gp90 IncA PF04156.9 ETO11956.1 - 0.00073 19.1 0.2 0.00073 19.1 0.1 2.5 3 0 0 3 3 3 1 IncA protein TMF_TATA_bd PF12325.3 ETO11956.1 - 0.0016 18.1 8.7 0.0016 18.1 6.0 3.0 3 0 0 3 3 3 1 TATA element modulatory factor 1 TATA binding Prefoldin_2 PF01920.15 ETO11956.1 - 0.0024 17.6 6.8 0.41 10.4 0.0 3.5 2 1 1 3 3 3 2 Prefoldin subunit BLOC1_2 PF10046.4 ETO11956.1 - 0.0073 16.4 2.5 0.0073 16.4 1.7 2.1 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 UvrD-helicase PF00580.16 ETO11956.1 - 0.012 14.9 0.1 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF342 PF03961.8 ETO11956.1 - 0.017 13.5 0.2 0.017 13.5 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Tox-REase-7 PF15649.1 ETO11956.1 - 0.018 15.1 0.3 0.36 11.0 0.1 2.6 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 7 Syntaxin-6_N PF09177.6 ETO11956.1 - 0.13 12.6 3.8 0.19 12.1 0.6 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF641 PF04859.7 ETO11956.1 - 0.13 11.9 7.5 3.4 7.4 2.4 2.5 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF3450 PF11932.3 ETO11956.1 - 0.24 10.6 7.0 0.024 13.9 1.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF2433 PF10360.4 ETO11956.1 - 0.32 11.3 2.9 2.1 8.6 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2433) FliJ PF02050.11 ETO11956.1 - 0.52 10.3 19.4 0.61 10.1 1.4 3.0 3 0 0 3 3 3 0 Flagellar FliJ protein ISG65-75 PF11727.3 ETO11956.1 - 1 8.3 7.6 2.9 6.8 0.1 2.6 3 0 0 3 3 3 0 Invariant surface glycoprotein DUF4164 PF13747.1 ETO11956.1 - 2.9 8.0 7.1 16 5.7 1.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) CENP-Q PF13094.1 ETO11956.1 - 3.6 7.5 11.1 14 5.6 3.7 2.5 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit HTH_3 PF01381.17 ETO11957.1 - 5.8e-11 42.0 0.0 8.1e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 ETO11957.1 - 6.4e-08 32.6 0.0 8.6e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 ETO11957.1 - 1.3e-06 28.3 0.0 2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.1 ETO11957.1 - 0.00015 21.3 0.0 0.00024 20.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.1 ETO11957.1 - 0.031 14.0 0.1 0.052 13.3 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain D123 PF07065.9 ETO11958.1 - 1.4e-21 76.8 4.1 1.4e-21 76.8 2.8 2.8 2 1 0 2 2 2 2 D123 SET PF00856.23 ETO11958.1 - 2.6e-11 44.0 3.4 9.9e-09 35.6 0.1 3.8 4 0 0 4 4 4 2 SET domain DUF4343 PF14243.1 ETO11958.1 - 4.8e-06 26.4 0.2 2.1e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4343) DUF1993 PF09351.5 ETO11958.1 - 0.031 14.2 0.5 0.031 14.2 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) Nucleoside_tran PF01733.13 ETO11959.1 - 1.1e-12 47.7 7.1 1.1e-12 47.7 4.9 2.6 2 1 0 3 3 3 1 Nucleoside transporter Herpes_US9 PF06072.6 ETO11959.1 - 0.68 9.8 0.1 0.68 9.8 0.1 2.6 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 Nucleoside_tran PF01733.13 ETO11960.1 - 3.6e-18 65.7 18.2 7.8e-17 61.3 6.4 2.2 1 1 1 2 2 2 2 Nucleoside transporter Cys_Met_Meta_PP PF01053.15 ETO11961.1 - 5.1e-32 110.6 0.2 1.5e-21 76.1 0.0 2.5 1 1 1 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme EF-hand_1 PF00036.27 ETO11962.1 - 3e-12 44.8 0.0 2.8e-06 26.2 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 ETO11962.1 - 5.3e-12 45.7 0.0 9.5e-10 38.4 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 ETO11962.1 - 9.9e-11 41.0 0.0 4.4e-07 29.4 0.0 3.1 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 ETO11962.1 - 4.1e-09 35.5 0.0 6.5e-06 25.6 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_9 PF14658.1 ETO11962.1 - 1.2e-07 31.5 0.0 6.8e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 ETO11962.1 - 0.00046 19.3 0.0 0.012 14.8 0.0 2.5 3 0 0 3 3 3 1 EF hand DUF2608 PF11019.3 ETO11962.1 - 0.044 12.7 0.0 0.048 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) Phi_1 PF04674.7 ETO11962.1 - 0.046 12.8 0.0 0.046 12.8 0.0 1.1 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region YqeY PF09424.5 ETO11962.1 - 0.089 12.6 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Yqey-like protein WD-3 PF09765.4 ETO11963.1 - 0.044 13.0 0.2 1.2 8.3 0.1 2.4 2 1 1 3 3 3 0 WD-repeat region Skp1 PF01466.14 ETO11964.1 - 1.3e-38 130.8 0.7 1.3e-38 130.8 0.5 1.8 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Myotub-related PF06602.9 ETO11966.1 - 2.7e-05 23.1 1.0 0.00026 19.8 0.1 2.0 1 1 0 2 2 2 2 Myotubularin-like phosphatase domain DIM1 PF02966.11 ETO11966.1 - 0.11 11.9 1.0 0.29 10.6 0.1 1.9 2 0 0 2 2 2 0 Mitosis protein DIM1 Ras PF00071.17 ETO11967.1 - 5.5e-43 146.1 0.4 6.6e-43 145.9 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO11967.1 - 4.1e-09 36.9 0.0 9.5e-09 35.7 0.0 1.6 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO11967.1 - 8.1e-09 34.9 0.0 9.5e-09 34.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETO11967.1 - 4.5e-05 22.7 0.0 5.5e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 ETO11967.1 - 0.037 13.5 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein V_ATPase_I PF01496.14 ETO11968.1 - 3.5e-145 484.8 11.0 4e-145 484.6 7.6 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Zip PF02535.17 ETO11968.1 - 0.00052 19.1 0.5 0.0019 17.2 0.3 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter Tmemb_9 PF05434.6 ETO11968.1 - 0.0049 16.6 0.1 0.012 15.3 0.1 1.7 1 0 0 1 1 1 1 TMEM9 Pkinase PF00069.20 ETO11969.1 - 6.5e-10 38.5 0.4 2.9e-07 29.9 0.3 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO11969.1 - 0.0032 16.5 0.1 0.16 11.0 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase rve PF00665.21 ETO11969.1 - 0.037 14.1 0.0 0.27 11.3 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain Meleagrin PF08189.6 ETO11970.1 - 0.015 14.7 0.1 0.031 13.7 0.1 1.4 1 0 0 1 1 1 0 Meleagrin/Cygnin family Hepatitis_core PF00906.15 ETO11970.1 - 0.16 11.5 1.2 4.9 6.7 0.1 2.9 3 1 0 3 3 3 0 Hepatitis core antigen WD40 PF00400.27 ETO11973.1 - 1.2e-06 28.1 2.2 5.3e-05 22.9 0.1 3.7 4 0 0 4 4 4 1 WD domain, G-beta repeat zf-C3HC4_2 PF13923.1 ETO11974.1 - 1.3 9.1 6.3 0.54 10.3 0.8 2.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC PF07967.8 ETO11977.1 - 0.00038 20.2 1.0 0.00051 19.8 0.5 1.4 1 1 0 1 1 1 1 C3HC zinc finger-like TPP_enzyme_N PF02776.13 ETO11978.1 - 4.9e-38 130.3 0.0 7.1e-38 129.7 0.0 1.1 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain POR_N PF01855.14 ETO11978.1 - 0.0032 16.9 0.0 0.0043 16.5 0.0 1.1 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg DoxX PF07681.7 ETO11981.1 - 6.3e-06 26.5 9.0 1.1e-05 25.7 6.3 1.4 1 0 0 1 1 1 1 DoxX DUF3585 PF12130.3 ETO11981.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3585) ABC_membrane_3 PF13748.1 ETO11981.1 - 0.061 12.3 1.6 0.11 11.5 1.1 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region HR_lesion PF05514.6 ETO11981.1 - 0.32 10.8 6.4 0.26 11.1 0.7 2.5 2 1 0 2 2 2 0 HR-like lesion-inducing Phage_holin_4 PF05105.7 ETO11981.1 - 1.5 8.4 6.1 1 9.0 0.6 2.4 3 0 0 3 3 3 0 Holin family MSP1_C PF07462.6 ETO11982.1 - 0.61 8.3 11.0 1 7.6 7.6 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus WD40 PF00400.27 ETO11983.1 - 6.8e-07 28.9 0.1 0.043 13.7 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat RINGv PF12906.2 ETO11983.1 - 0.077 13.0 2.4 0.22 11.6 1.7 1.8 1 0 0 1 1 1 0 RING-variant domain Thioredoxin PF00085.15 ETO11984.1 - 1.2e-26 92.4 0.2 5.5e-20 70.9 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin ERp29 PF07749.7 ETO11984.1 - 4.3e-11 43.3 0.0 8e-10 39.2 0.0 2.5 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain ERp29_N PF07912.8 ETO11984.1 - 0.052 13.4 0.1 0.47 10.3 0.0 2.3 2 0 0 2 2 2 0 ERp29, N-terminal domain HyaE PF07449.6 ETO11984.1 - 0.14 12.0 0.0 0.44 10.4 0.0 1.7 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Nol1_Nop2_Fmu PF01189.12 ETO11985.1 - 2.4e-15 56.6 0.1 4.6e-09 36.0 0.1 2.4 2 0 0 2 2 2 2 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 ETO11985.1 - 0.087 12.8 0.0 0.13 12.3 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain HD PF01966.17 ETO11986.1 - 1.2e-06 28.4 0.9 2.1e-06 27.7 0.6 1.4 1 0 0 1 1 1 1 HD domain DUF4473 PF14747.1 ETO11986.1 - 0.0085 16.2 0.3 0.024 14.8 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4473) Herpes_UL37_2 PF07413.6 ETO11986.1 - 0.035 12.8 5.1 4.5 6.0 0.0 2.3 2 0 0 2 2 2 0 Betaherpesvirus immediate-early glycoprotein UL37 ABC_tran_2 PF12848.2 ETO11986.1 - 0.16 11.8 4.5 0.099 12.4 0.7 2.2 2 0 0 2 2 2 0 ABC transporter NgoMIV_restric PF09015.5 ETO11987.1 - 0.015 14.2 0.1 0.018 14.0 0.1 1.0 1 0 0 1 1 1 0 NgoMIV restriction enzyme DUF3092 PF11289.3 ETO11988.1 - 0.051 12.8 3.5 0.058 12.6 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3092) WD40 PF00400.27 ETO11990.1 - 5.8e-68 222.5 20.5 1.1e-13 50.4 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO11990.1 - 6.5e-09 35.7 0.5 7.1e-05 22.6 0.1 2.8 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO11990.1 - 2.5e-08 32.6 0.9 0.012 13.9 0.3 3.0 1 1 3 4 4 4 3 Cytochrome D1 heme domain Nup160 PF11715.3 ETO11990.1 - 3.7e-05 22.0 7.9 1.1 7.3 0.2 4.8 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO11990.1 - 0.012 14.4 8.9 0.56 8.9 0.1 3.7 1 1 3 4 4 4 0 Nup133 N terminal like PLD_C PF12357.3 ETO11990.1 - 0.062 12.8 2.9 3.4 7.2 0.0 4.0 4 1 0 5 5 5 0 Phospholipase D C terminal DUF1513 PF07433.6 ETO11990.1 - 0.12 11.2 0.2 4.7 6.0 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1513) PD40 PF07676.7 ETO11990.1 - 0.58 9.8 4.9 46 3.8 0.0 4.1 3 1 1 4 4 4 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 ETO11990.1 - 0.59 9.5 11.3 8.4 5.8 0.0 5.1 6 1 0 6 6 6 0 Proteasome subunit A N-terminal signature HALZ PF02183.13 ETO11991.1 - 0.00027 20.5 12.9 0.0018 17.9 3.1 5.4 5 1 1 6 6 6 2 Homeobox associated leucine zipper Laminin_II PF06009.7 ETO11991.1 - 0.0045 16.7 3.4 0.0045 16.7 2.4 3.3 1 1 2 3 3 2 1 Laminin Domain II Prefoldin PF02996.12 ETO11991.1 - 0.013 15.1 3.2 0.013 15.1 2.2 5.5 3 2 2 5 5 5 0 Prefoldin subunit GAS PF13851.1 ETO11991.1 - 0.19 10.8 45.6 0.38 9.9 6.9 3.3 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF724 PF05266.9 ETO11991.1 - 1.4 8.4 35.9 0.79 9.3 4.2 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF724) DUF3450 PF11932.3 ETO11991.1 - 1.7 7.8 47.9 0.22 10.7 3.9 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) DUF1647 PF07801.6 ETO11991.1 - 2.2 7.8 7.4 0.58 9.6 0.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1647) Syntaxin-6_N PF09177.6 ETO11991.1 - 3.7 8.0 32.1 0.047 14.0 1.7 4.3 1 1 3 4 4 4 0 Syntaxin 6, N-terminal ATP-synt_D PF01813.12 ETO11991.1 - 5.4 6.5 24.0 0.34 10.4 5.1 3.6 1 1 2 4 4 4 0 ATP synthase subunit D DUF904 PF06005.7 ETO11991.1 - 5.7 7.3 48.4 0.74 10.1 6.8 5.1 2 2 1 3 3 3 0 Protein of unknown function (DUF904) DUF3584 PF12128.3 ETO11991.1 - 7.8 3.6 47.0 0.33 8.2 5.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) V_ATPase_I PF01496.14 ETO11991.1 - 8.5 4.0 33.7 2.7 5.7 3.8 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Ank_2 PF12796.2 ETO11992.1 - 4.8e-38 129.3 4.1 2.7e-18 66.0 0.1 3.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETO11992.1 - 9.1e-30 100.9 1.6 1.9e-10 39.9 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 ETO11992.1 - 1.2e-23 82.6 1.8 2.6e-08 33.8 0.1 5.5 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO11992.1 - 2.1e-23 80.0 0.1 2.9e-06 26.9 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 ETO11992.1 - 1.9e-21 76.0 0.9 2.1e-12 47.1 0.0 4.7 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Laminin_II PF06009.7 ETO11992.1 - 5.6 6.7 19.6 2.6 7.8 8.9 2.8 3 0 0 3 3 3 0 Laminin Domain II RRM_6 PF14259.1 ETO11993.1 - 0.00012 22.0 0.0 0.0003 20.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Glyco_tranf_2_4 PF13704.1 ETO11994.1 - 1.6e-06 28.3 1.8 6.1e-06 26.4 1.2 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 2 Pex14_N PF04695.8 ETO11994.1 - 0.12 12.4 2.0 0.26 11.3 1.4 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Secretin_N_2 PF07655.8 ETO11994.1 - 4.6 7.6 23.3 1.6 9.1 12.1 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain Glyco_hydro_47 PF01532.15 ETO11996.1 - 2.2e-62 211.2 0.0 5.2e-61 206.6 0.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Cmc1 PF08583.5 ETO11998.1 - 0.00036 20.2 4.7 0.00068 19.3 3.2 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Pepsin-I3 PF06394.8 ETO11998.1 - 0.2 11.3 1.5 0.32 10.6 0.3 1.9 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain TPR_19 PF14559.1 ETO11999.1 - 1.3e-06 28.6 0.4 0.047 14.0 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO11999.1 - 0.0002 21.6 0.0 2.8 8.8 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO11999.1 - 0.00071 19.2 3.5 0.051 13.5 0.0 3.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO11999.1 - 0.0037 17.6 0.8 4.4 7.9 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO11999.1 - 0.0041 16.7 0.4 0.12 12.0 0.1 2.8 2 1 1 3 3 3 1 TPR repeat TPR_17 PF13431.1 ETO11999.1 - 0.021 15.0 3.4 0.076 13.2 0.0 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETO11999.1 - 0.022 15.4 0.1 4.1 8.1 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETO11999.1 - 0.025 14.3 0.0 0.62 9.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETO11999.1 - 0.038 13.6 0.2 1.6 8.4 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2811 PF10929.3 ETO11999.1 - 0.055 13.4 0.9 6.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2811) TPR_11 PF13414.1 ETO12000.1 - 0.00082 18.9 1.3 0.0045 16.6 0.1 2.5 2 1 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 ETO12000.1 - 0.0076 16.1 2.3 0.071 13.0 0.1 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO12000.1 - 0.027 14.3 1.4 0.56 10.2 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETO12000.1 - 0.034 13.9 1.7 0.77 9.6 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETO12000.1 - 0.5 10.0 3.6 2.4 7.9 0.7 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_transf_20 PF00982.16 ETO12001.1 - 3.8e-106 355.4 0.0 2.6e-105 352.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 ETO12001.1 - 8.1e-41 139.4 0.0 2.8e-40 137.7 0.0 1.8 2 0 0 2 2 2 1 Trehalose-phosphatase Glycos_transf_1 PF00534.15 ETO12001.1 - 0.019 14.3 0.0 0.055 12.8 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferases group 1 Syntaxin_2 PF14523.1 ETO12002.1 - 0.00096 19.1 9.3 0.00096 19.1 6.5 1.8 2 0 0 2 2 2 1 Syntaxin-like protein YlqD PF11068.3 ETO12002.1 - 0.018 15.0 1.8 0.018 15.0 1.3 2.9 1 1 1 3 3 3 0 YlqD protein Enkurin PF13864.1 ETO12002.1 - 0.041 14.0 2.1 0.041 14.0 1.4 2.5 3 0 0 3 3 3 0 Calmodulin-binding T2SF PF00482.18 ETO12002.1 - 0.073 12.9 0.8 0.3 11.0 0.0 2.0 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F BLOC1_2 PF10046.4 ETO12002.1 - 0.25 11.5 10.9 0.38 10.9 0.6 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4375 PF14300.1 ETO12002.1 - 0.29 11.1 5.8 0.28 11.1 0.2 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4375) Syntaxin-6_N PF09177.6 ETO12002.1 - 1.1 9.6 9.3 0.36 11.2 0.3 3.1 2 1 1 3 3 3 0 Syntaxin 6, N-terminal GAS PF13851.1 ETO12002.1 - 1.3 8.1 13.8 6.8 5.8 9.6 2.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Ax_dynein_light PF10211.4 ETO12002.1 - 1.4 8.6 14.1 2.6 7.8 4.7 2.6 1 1 2 3 3 3 0 Axonemal dynein light chain AKNA PF12443.3 ETO12002.1 - 6 6.9 8.8 20 5.2 0.1 3.0 2 1 1 3 3 3 0 AT-hook-containing transcription factor Mucin PF01456.12 ETO12003.1 - 6.7 6.4 13.4 0.061 13.0 3.5 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein EF-hand_1 PF00036.27 ETO12004.1 - 1.2e-06 27.3 0.2 0.00023 20.2 0.0 3.1 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 ETO12004.1 - 2e-05 24.0 0.2 0.0023 17.6 0.1 3.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 ETO12004.1 - 4.5e-05 22.5 0.2 0.00017 20.7 0.2 2.0 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 ETO12004.1 - 5.3e-05 23.2 1.4 0.00011 22.2 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair DUF1754 PF08555.5 ETO12004.1 - 3 8.5 8.7 6.1 7.5 6.0 1.4 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) WD40 PF00400.27 ETO12006.1 - 1.4e-49 164.2 19.8 2.8e-11 42.8 0.9 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO12006.1 - 1.4e-05 23.4 2.7 0.16 10.0 0.0 3.9 2 1 1 4 4 4 4 Nucleoporin Nup120/160 Ank_4 PF13637.1 ETO12008.1 - 5.5e-15 55.4 0.4 2.8e-07 30.8 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO12008.1 - 4.3e-09 36.6 0.2 1.4e-05 25.2 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO12008.1 - 1.6e-07 31.3 0.3 4e-07 30.0 0.2 1.7 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 ETO12008.1 - 2e-06 27.3 0.1 0.025 14.3 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 ETO12008.1 - 3.5e-06 26.7 0.1 0.0032 17.5 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat RNF111_N PF15303.1 ETO12009.1 - 2.9e-05 23.7 3.6 4.6e-05 23.0 2.5 1.2 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase Arkadia N-terminus YMF19 PF02326.10 ETO12010.1 - 0.046 14.2 4.4 0.046 14.2 3.1 4.0 2 1 2 4 4 4 0 Plant ATP synthase F0 C2 PF00168.25 ETO12011.1 - 1.3e-20 73.0 0.3 2.7e-20 72.0 0.2 1.6 1 0 0 1 1 1 1 C2 domain Tropomyosin_1 PF12718.2 ETO12011.1 - 1.1e-06 28.5 64.3 0.00011 22.0 14.9 4.6 1 1 4 5 5 5 3 Tropomyosin like ADIP PF11559.3 ETO12011.1 - 1.1e-06 28.6 40.0 9.5e-05 22.3 11.2 5.6 1 1 6 7 7 7 5 Afadin- and alpha -actinin-Binding BLOC1_2 PF10046.4 ETO12011.1 - 1e-05 25.5 20.7 0.00019 21.5 3.2 7.1 2 1 5 7 7 6 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF869 PF05911.6 ETO12011.1 - 4.8e-05 21.8 75.8 0.012 13.8 30.8 3.1 1 1 1 2 2 2 2 Plant protein of unknown function (DUF869) Myosin_tail_1 PF01576.14 ETO12011.1 - 0.00033 18.5 83.8 0.0017 16.1 58.1 2.3 1 1 0 1 1 1 1 Myosin tail GAS PF13851.1 ETO12011.1 - 0.00035 19.8 89.8 0.013 14.6 17.7 4.6 1 1 3 4 4 4 4 Growth-arrest specific micro-tubule binding M PF02370.11 ETO12011.1 - 0.00036 20.5 15.8 0.009 16.2 0.4 12.4 10 4 4 16 16 10 5 M protein repeat IncA PF04156.9 ETO12011.1 - 0.00055 19.5 21.6 0.00055 19.5 15.0 5.1 1 1 4 5 5 5 3 IncA protein CCDC155 PF14662.1 ETO12011.1 - 0.00099 18.7 86.6 0.072 12.6 33.6 3.9 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 bZIP_2 PF07716.10 ETO12011.1 - 0.0036 17.1 1.9 0.0036 17.1 1.3 9.5 5 3 4 9 9 9 4 Basic region leucine zipper DUF904 PF06005.7 ETO12011.1 - 0.0044 17.2 16.5 0.0044 17.2 11.4 7.7 1 1 5 6 6 4 2 Protein of unknown function (DUF904) CENP-F_leu_zip PF10473.4 ETO12011.1 - 0.0056 16.5 28.9 0.0056 16.5 20.0 5.0 1 1 4 5 5 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.6 ETO12011.1 - 0.0066 16.2 12.4 0.0066 16.2 8.6 4.4 1 1 4 5 5 5 2 Autophagy protein 16 (ATG16) CC2D2AN-C2 PF15625.1 ETO12011.1 - 0.0072 15.8 0.0 0.021 14.2 0.0 1.7 1 0 0 1 1 1 1 CC2D2A N-terminal C2 domain PspA_IM30 PF04012.7 ETO12011.1 - 0.012 14.9 5.1 0.012 14.9 3.5 5.5 1 1 4 5 5 5 0 PspA/IM30 family Reo_sigmaC PF04582.7 ETO12011.1 - 0.022 13.9 24.6 0.014 14.6 1.7 3.4 1 1 1 3 3 3 0 Reovirus sigma C capsid protein bZIP_1 PF00170.16 ETO12011.1 - 0.03 14.2 1.5 0.024 14.6 2.9 9.2 3 1 6 9 9 8 0 bZIP transcription factor HOOK PF05622.7 ETO12011.1 - 0.037 11.8 82.1 0.81 7.4 23.2 3.0 1 1 1 2 2 2 0 HOOK protein HALZ PF02183.13 ETO12011.1 - 0.083 12.6 64.6 0.028 14.1 1.4 7.4 4 2 2 6 6 6 0 Homeobox associated leucine zipper UPF0184 PF03670.8 ETO12011.1 - 0.18 12.0 22.6 0.096 12.8 2.1 4.2 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) APG6 PF04111.7 ETO12011.1 - 0.48 9.4 91.7 0.52 9.3 21.6 4.2 2 1 3 5 5 5 0 Autophagy protein Apg6 Tropomyosin PF00261.15 ETO12011.1 - 0.55 9.2 74.5 0.016 14.3 37.3 3.0 1 1 1 2 2 1 0 Tropomyosin MAD PF05557.8 ETO12011.1 - 1.2 7.1 88.1 0.21 9.6 29.6 2.8 1 1 1 2 2 2 0 Mitotic checkpoint protein DUF3287 PF11690.3 ETO12011.1 - 2.7 8.0 38.6 0.37 10.8 3.1 6.2 1 1 4 6 6 6 0 Protein of unknown function (DUF3287) DUF972 PF06156.8 ETO12011.1 - 4 7.8 75.5 0.069 13.5 4.7 7.3 2 1 5 7 7 7 0 Protein of unknown function (DUF972) WXG100 PF06013.7 ETO12011.1 - 4.6 7.3 41.6 0.66 10.0 3.7 6.8 4 2 4 8 8 6 0 Proteins of 100 residues with WXG Spc7 PF08317.6 ETO12011.1 - 7.1 5.1 76.7 0.055 12.1 14.8 3.9 1 1 3 4 4 4 0 Spc7 kinetochore protein DMPK_coil PF08826.5 ETO12011.1 - 7.3 6.5 72.6 0.023 14.6 7.3 7.6 4 2 2 7 7 7 0 DMPK coiled coil domain like TOBE_2 PF08402.5 ETO12012.1 - 0.11 12.4 0.1 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 TOBE domain Band_3_cyto PF07565.8 ETO12012.1 - 2 7.8 5.5 2.3 7.6 3.8 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SAM_2 PF07647.12 ETO12014.1 - 0.02 14.7 1.4 3.3 7.6 0.0 2.9 2 1 1 3 3 3 0 SAM domain (Sterile alpha motif) Daxx PF03344.10 ETO12014.1 - 0.61 8.5 11.8 0.58 8.5 8.2 1.1 1 0 0 1 1 1 0 Daxx Family Drc1-Sld2 PF11719.3 ETO12014.1 - 1.1 8.2 6.8 1.3 8.0 4.7 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein DUF2457 PF10446.4 ETO12014.1 - 3 6.4 14.1 3 6.4 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TRAP_alpha PF03896.11 ETO12014.1 - 9 5.1 12.3 12 4.7 8.5 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF3115 PF11312.3 ETO12015.1 - 0.016 14.0 0.0 0.018 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3115) IL7 PF01415.11 ETO12016.1 - 0.0082 15.7 0.7 0.0082 15.7 0.5 2.2 2 0 0 2 2 2 1 Interleukin 7/9 family EnY2 PF10163.4 ETO12016.1 - 0.056 13.3 0.2 0.056 13.3 0.1 3.0 3 1 0 3 3 3 0 Transcription factor e(y)2 DUF3391 PF11871.3 ETO12016.1 - 0.2 11.8 3.2 0.25 11.5 0.8 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) YojJ PF10372.4 ETO12018.1 - 0.0042 16.9 2.3 0.0073 16.1 1.6 1.4 1 1 0 1 1 1 1 Bacterial membrane-spanning protein N-terminus DUF4446 PF14584.1 ETO12018.1 - 0.017 14.9 2.4 0.022 14.6 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF4298 PF14131.1 ETO12018.1 - 0.024 14.5 0.5 0.024 14.5 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4298) DUF2228 PF10228.4 ETO12018.1 - 0.042 13.3 2.3 0.048 13.2 1.6 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) DUF1640 PF07798.6 ETO12018.1 - 0.049 13.6 6.3 0.065 13.2 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) LIF_OSM PF01291.12 ETO12018.1 - 0.07 13.0 2.2 0.11 12.4 1.5 1.3 1 1 0 1 1 1 0 LIF / OSM family EMP24_GP25L PF01105.19 ETO12018.1 - 0.13 11.9 4.3 0.17 11.5 3.0 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD SLX9 PF15341.1 ETO12018.1 - 0.13 12.6 7.3 0.2 12.1 5.0 1.3 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 FlaC_arch PF05377.6 ETO12018.1 - 0.19 11.6 2.7 0.13 12.1 0.5 1.8 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) SopA_C PF13979.1 ETO12018.1 - 0.36 10.4 3.8 0.45 10.1 2.7 1.2 1 0 0 1 1 1 0 SopA-like catalytic domain Luteo_P1-P2 PF08467.5 ETO12018.1 - 0.84 8.3 5.0 0.95 8.1 3.5 1.0 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase IncA PF04156.9 ETO12018.1 - 5 6.6 7.8 7 6.2 5.4 1.3 1 0 0 1 1 1 0 IncA protein DUF342 PF03961.8 ETO12018.1 - 7.1 4.9 10.3 7.5 4.8 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) WD40 PF00400.27 ETO12019.1 - 0.00036 20.3 1.9 0.00042 20.1 0.6 1.6 1 1 1 2 2 2 1 WD domain, G-beta repeat HAP1_N PF04849.8 ETO12019.1 - 0.02 13.8 4.3 0.022 13.6 3.0 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Rootletin PF15035.1 ETO12019.1 - 0.025 14.5 6.6 0.033 14.1 4.6 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF641 PF04859.7 ETO12019.1 - 0.045 13.5 7.0 0.055 13.2 4.9 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF2681 PF10883.3 ETO12019.1 - 0.073 13.2 8.4 0.17 12.0 5.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) CENP-F_leu_zip PF10473.4 ETO12019.1 - 0.092 12.6 7.7 0.11 12.3 5.3 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 ETO12019.1 - 0.099 12.2 7.4 0.11 12.1 5.1 1.1 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 ETO12019.1 - 0.13 11.2 7.3 0.16 11.0 5.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 MSC PF09402.5 ETO12019.1 - 0.14 10.8 5.8 0.16 10.6 4.0 1.0 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Atg14 PF10186.4 ETO12019.1 - 0.22 10.4 4.8 0.23 10.3 3.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 ETO12019.1 - 0.95 8.0 10.7 1.2 7.7 7.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF972 PF06156.8 ETO12019.1 - 1.2 9.5 6.4 1.7 9.0 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF948 PF06103.6 ETO12019.1 - 2.4 8.0 4.6 3.8 7.4 3.2 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF2508 PF10704.4 ETO12019.1 - 2.9 8.1 6.9 4.8 7.4 4.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2508) Protocadherin PF08374.6 ETO12020.1 - 0.26 10.9 1.7 0.31 10.6 1.2 1.1 1 0 0 1 1 1 0 Protocadherin Menin PF05053.8 ETO12021.1 - 0.053 11.6 6.1 0.069 11.3 4.2 1.3 1 0 0 1 1 1 0 Menin Macoilin PF09726.4 ETO12021.1 - 0.12 10.5 12.9 0.16 10.2 8.9 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4661 PF15576.1 ETO12021.1 - 4.7 6.7 6.5 14 5.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4661) Herpes_LMP1 PF05297.6 ETO12021.1 - 7.8 5.3 9.8 11 4.8 6.8 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) XAP5 PF04921.9 ETO12021.1 - 8.4 5.8 10.0 14 5.1 7.0 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator EST1_DNA_bind PF10373.4 ETO12022.1 - 1.7e-22 79.9 16.9 1.1e-21 77.3 11.7 2.3 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 ETO12022.1 - 1e-06 28.7 0.2 1e-06 28.7 0.1 3.5 3 2 0 3 3 3 1 Telomerase activating protein Est1 THAP PF05485.7 ETO12022.1 - 0.08 13.1 2.7 0.098 12.8 0.4 2.2 2 0 0 2 2 2 0 THAP domain Serinc PF03348.10 ETO12023.1 - 2.7e-52 177.9 22.1 1.1e-44 152.8 2.1 3.1 2 2 1 3 3 3 2 Serine incorporator (Serinc) ECIST_Cterm PF14784.1 ETO12023.1 - 0.15 12.0 1.4 0.27 11.1 0.2 1.9 2 0 0 2 2 2 0 C-terminal domain of the ECSIT protein DUF4407 PF14362.1 ETO12024.1 - 0.27 10.1 3.8 0.3 9.9 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DDHD PF02862.12 ETO12024.1 - 3.4 7.3 9.0 4 7.1 6.2 1.1 1 0 0 1 1 1 0 DDHD domain RNase_H2-Ydr279 PF09468.5 ETO12024.1 - 8.5 5.4 14.5 11 5.1 10.0 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) TPR_12 PF13424.1 ETO12025.1 - 5.9e-39 131.8 5.0 3.7e-13 49.2 0.2 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO12025.1 - 1.7e-22 78.7 19.8 5.8e-11 41.8 0.8 3.7 2 1 2 4 4 4 4 TPR repeat TPR_2 PF07719.12 ETO12025.1 - 7.6e-20 69.1 11.6 1e-05 25.0 0.2 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO12025.1 - 7.2e-17 60.7 0.0 0.00041 20.1 0.0 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO12025.1 - 3.9e-16 57.8 21.2 2.8e-05 23.5 0.4 5.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO12025.1 - 7e-14 50.4 21.1 3.5e-05 23.2 0.7 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO12025.1 - 1.1e-13 49.8 1.2 0.00066 19.2 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO12025.1 - 9.8e-09 34.7 7.7 0.37 11.1 0.0 5.8 6 1 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO12025.1 - 1.4e-08 35.1 0.0 0.059 14.0 0.0 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO12025.1 - 7.8e-07 29.1 2.9 0.089 13.2 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO12025.1 - 3.3e-05 24.1 0.0 2.4 9.0 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.7 ETO12025.1 - 6e-05 22.7 6.7 0.079 12.7 0.1 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO12025.1 - 9e-05 22.5 12.4 0.026 14.6 3.1 4.0 1 1 4 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 DUF627 PF04781.7 ETO12025.1 - 0.0033 17.0 3.2 1.7 8.3 0.3 3.2 2 1 0 2 2 2 1 Protein of unknown function (DUF627) MIT PF04212.13 ETO12025.1 - 0.02 14.7 4.3 0.27 11.1 0.0 3.9 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.4 ETO12025.1 - 0.45 9.8 3.4 2.2 7.5 0.0 3.1 4 0 0 4 4 4 0 SHNi-TPR PRD PF00874.15 ETO12025.1 - 0.77 9.9 3.9 2 8.6 0.1 2.6 3 0 0 3 3 3 0 PRD domain Kelch_6 PF13964.1 ETO12026.1 - 8.9e-08 31.9 7.5 0.00016 21.7 0.0 5.0 4 2 1 5 5 5 2 Kelch motif Kelch_5 PF13854.1 ETO12026.1 - 3.2e-06 26.9 1.5 0.24 11.3 0.1 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO12026.1 - 7.6e-06 25.9 1.2 7.7e-05 22.7 0.0 3.2 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO12026.1 - 9.8e-06 25.0 4.5 0.0088 15.5 0.1 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO12026.1 - 1.6e-05 24.5 5.4 0.0016 18.1 0.1 4.3 5 0 0 5 5 5 1 Galactose oxidase, central domain Ribosomal_60s PF00428.14 ETO12027.1 - 3.3e-15 56.2 14.3 8.8e-15 54.8 9.9 1.6 1 1 0 1 1 1 1 60s Acidic ribosomal protein Jag_N PF14804.1 ETO12027.1 - 0.0046 16.9 0.1 0.011 15.7 0.0 1.6 2 0 0 2 2 2 1 Jag N-terminus WD40 PF00400.27 ETO12028.1 - 4.3e-65 213.4 18.7 8.1e-14 50.8 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO12028.1 - 2.6e-11 43.6 3.5 2.6e-05 24.0 0.4 2.7 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO12028.1 - 8.7e-07 27.4 5.0 0.068 11.2 0.0 3.8 1 1 3 4 4 4 3 Nucleoporin Nup120/160 DPPIV_N PF00930.16 ETO12028.1 - 0.00031 19.4 0.2 0.21 10.1 0.0 3.3 2 1 0 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.7 ETO12028.1 - 0.00042 19.9 12.4 1.9 8.2 0.1 6.2 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 ETO12028.1 - 0.0068 15.5 2.9 12 4.8 0.0 4.3 1 1 4 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 ETO12028.1 - 0.019 13.3 0.1 1.1 7.5 0.0 2.7 2 1 0 3 3 3 0 Cytochrome D1 heme domain Resistin PF06954.6 ETO12028.1 - 0.14 12.4 3.3 89 3.4 0.0 4.5 3 3 1 4 4 4 0 Resistin WD40 PF00400.27 ETO12029.1 - 6e-65 212.9 14.1 2.9e-12 45.9 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Str_synth PF03088.11 ETO12029.1 - 1.5e-08 34.5 0.2 0.13 12.2 0.0 4.5 3 2 1 4 4 4 3 Strictosidine synthase eIF2A PF08662.6 ETO12029.1 - 1.5e-08 34.5 0.5 0.0058 16.3 0.0 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO12029.1 - 0.00016 21.2 9.1 15 5.3 0.0 6.1 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.2 ETO12029.1 - 0.00021 21.0 0.3 0.28 10.8 0.1 3.3 2 1 1 3 3 3 3 Transcription factor IIIC subunit delta N-term PQQ_2 PF13360.1 ETO12029.1 - 0.001 18.6 1.3 0.16 11.4 0.2 2.8 1 1 1 2 2 2 2 PQQ-like domain Nbas_N PF15492.1 ETO12029.1 - 0.0011 18.1 1.4 0.014 14.5 0.2 2.8 1 1 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal DUF1258 PF06869.7 ETO12029.1 - 0.0057 15.7 0.8 1.5 7.8 0.0 3.2 2 2 1 3 3 3 1 Protein of unknown function (DUF1258) IKI3 PF04762.7 ETO12029.1 - 0.017 12.9 0.1 0.032 12.0 0.0 1.5 1 1 0 1 1 1 0 IKI3 family BBS2_Mid PF14783.1 ETO12029.1 - 3.7 7.3 7.6 71 3.2 0.0 4.4 4 2 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region TPR_12 PF13424.1 ETO12030.1 - 9.1e-24 83.2 1.3 8.2e-11 41.6 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO12030.1 - 1.5e-12 46.9 2.9 3.6e-10 39.3 0.4 2.7 2 0 0 2 2 2 2 TPR repeat TPR_7 PF13176.1 ETO12030.1 - 1.1e-09 37.3 1.0 0.00012 21.6 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO12030.1 - 1.8e-09 36.7 14.5 1.6e-06 27.4 0.4 4.3 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO12030.1 - 4.7e-09 35.8 0.0 9.9e-05 22.1 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO12030.1 - 1.7e-08 33.6 13.2 1.4e-05 24.5 0.3 4.5 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO12030.1 - 1.5e-06 27.6 7.3 0.0058 16.4 0.3 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO12030.1 - 0.00023 21.1 3.6 0.026 14.6 0.0 4.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO12030.1 - 0.0024 18.3 0.1 0.23 12.1 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO12030.1 - 0.024 15.0 0.4 22 5.7 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETO12030.1 - 0.064 13.9 0.1 0.25 12.0 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Sel1 PF08238.7 ETO12030.1 - 0.086 13.5 2.1 0.85 10.3 0.4 2.6 2 0 0 2 2 2 0 Sel1 repeat Apc3 PF12895.2 ETO12030.1 - 0.091 12.9 7.1 0.052 13.6 1.2 2.8 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 ETO12030.1 - 0.3 10.9 6.4 11 5.9 0.1 3.6 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain DndB PF14072.1 ETO12032.1 - 0.061 12.4 4.2 0.077 12.1 2.9 1.1 1 0 0 1 1 1 0 DNA-sulfur modification-associated Agouti PF05039.7 ETO12032.1 - 6.9 7.0 10.2 7.5 6.9 6.6 1.4 1 1 0 1 1 1 0 Agouti protein Bacillus_HBL PF05791.6 ETO12034.1 - 0.25 10.7 4.2 0.8 9.0 0.2 2.2 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) VWA_2 PF13519.1 ETO12035.1 - 1.1e-09 38.6 0.0 2e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Helicase_C PF00271.26 ETO12035.1 - 0.0037 17.0 0.1 0.011 15.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CENP-M PF11111.3 ETO12036.1 - 0.00067 18.9 0.3 0.0015 17.8 0.2 1.5 1 0 0 1 1 1 1 Centromere protein M (CENP-M) Ras PF00071.17 ETO12039.1 - 2.5e-15 56.2 0.1 2.4e-13 49.8 0.0 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 ETO12039.1 - 2e-12 47.6 0.2 2.7e-12 47.2 0.2 1.1 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 ETO12039.1 - 0.00012 22.0 0.1 0.00022 21.1 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 ETO12039.1 - 0.00034 19.9 0.2 0.063 12.5 0.1 2.2 1 1 1 2 2 2 2 ADP-ribosylation factor family AAA_14 PF13173.1 ETO12039.1 - 0.0064 16.3 0.3 0.0078 16.1 0.2 1.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ETO12039.1 - 0.0067 16.5 0.1 0.014 15.5 0.1 1.6 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 ETO12039.1 - 0.011 15.4 0.3 0.012 15.3 0.2 1.2 1 0 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 ETO12039.1 - 0.035 14.3 0.1 0.041 14.1 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA PF00004.24 ETO12039.1 - 0.11 12.6 0.1 0.17 12.0 0.0 1.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) zf-RanBP PF00641.13 ETO12041.1 - 4.1e-07 28.9 1.9 8.7e-07 27.9 1.3 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Myc_N PF01056.13 ETO12042.1 - 0.31 10.1 8.7 0.9 8.6 1.9 2.3 2 0 0 2 2 2 0 Myc amino-terminal region EBV-NA3 PF05009.7 ETO12042.1 - 0.35 10.0 7.6 0.025 13.8 1.0 2.1 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Nucleoplasmin PF03066.10 ETO12042.1 - 1.6 8.2 12.1 0.1 12.0 1.9 2.4 2 0 0 2 2 2 0 Nucleoplasmin SAM_1 PF00536.25 ETO12044.1 - 6.1e-12 45.5 0.1 1.3e-11 44.4 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO12044.1 - 5.9e-10 38.8 0.1 1.2e-09 37.9 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Mem_trans PF03547.13 ETO12044.1 - 0.013 13.7 1.0 0.017 13.4 0.7 1.2 1 0 0 1 1 1 0 Membrane transport protein Sec10 PF07393.6 ETO12044.1 - 0.015 13.4 14.6 0.025 12.8 10.1 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec10 Zip PF02535.17 ETO12044.1 - 0.019 14.0 0.8 0.027 13.4 0.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter ETRAMP PF09716.5 ETO12044.1 - 0.023 14.6 18.7 1.2e+02 2.6 13.0 3.0 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) CDC45 PF02724.9 ETO12044.1 - 0.024 12.6 13.7 0.036 12.0 9.5 1.3 1 0 0 1 1 1 0 CDC45-like protein GAGA_bind PF06217.7 ETO12044.1 - 0.036 14.0 21.7 0.068 13.1 15.1 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family FLO_LFY PF01698.11 ETO12044.1 - 0.038 12.8 17.0 0.064 12.1 11.8 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein L_biotic_typeA PF04604.8 ETO12044.1 - 0.086 12.5 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Type-A lantibiotic DUF1510 PF07423.6 ETO12044.1 - 0.19 11.0 25.9 0.35 10.1 17.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) MIP-T3 PF10243.4 ETO12044.1 - 0.41 9.0 35.8 0.59 8.5 24.8 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DDHD PF02862.12 ETO12044.1 - 0.49 10.1 17.0 0.1 12.4 9.5 1.5 2 0 0 2 2 1 0 DDHD domain SOBP PF15279.1 ETO12044.1 - 1.2 9.4 11.7 0.41 10.9 6.4 1.5 2 0 0 2 2 1 0 Sine oculis-binding protein RR_TM4-6 PF06459.7 ETO12044.1 - 1.8 8.4 21.8 3.4 7.5 15.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3807 PF12720.2 ETO12044.1 - 2 8.5 23.3 4.4 7.4 16.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Ndc1_Nup PF09531.5 ETO12044.1 - 2.4 6.4 11.6 4 5.7 8.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Vfa1 PF08432.5 ETO12044.1 - 3.7 7.5 35.4 7.4 6.5 24.5 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2413 PF10310.4 ETO12044.1 - 6.1 5.5 25.2 9 4.9 17.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Band_3_cyto PF07565.8 ETO12044.1 - 7.7 5.9 11.8 13 5.2 7.7 1.8 2 0 0 2 2 2 0 Band 3 cytoplasmic domain LMBR1 PF04791.11 ETO12044.1 - 8.8 4.7 14.2 13 4.1 9.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein PMSR PF01625.16 ETO12045.1 - 0.014 15.2 1.4 0.33 10.8 0.0 2.3 2 0 0 2 2 2 0 Peptide methionine sulfoxide reductase DUF1021 PF06257.6 ETO12047.1 - 0.096 12.3 1.0 9.6 5.9 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1021) Peptidase_M15_2 PF05951.8 ETO12047.1 - 0.13 11.6 0.3 0.23 10.8 0.2 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) DUF4653 PF15546.1 ETO12047.1 - 1.6 7.9 5.4 1.2 8.3 1.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4653) P5-ATPase PF12409.3 ETO12047.1 - 3.3 7.5 7.4 0.88 9.4 2.6 2.1 2 2 0 2 2 2 0 P5-type ATPase cation transporter Ycf1 PF05758.7 ETO12048.1 - 0.004 14.9 4.0 0.0057 14.4 2.8 1.2 1 0 0 1 1 1 1 Ycf1 STAT_int PF02865.12 ETO12049.1 - 0.11 12.4 1.5 0.44 10.5 0.1 2.5 3 0 0 3 3 3 0 STAT protein, protein interaction domain Allexi_40kDa PF05549.6 ETO12049.1 - 0.35 10.1 4.4 2.4 7.4 0.0 2.3 1 1 1 2 2 2 0 Allexivirus 40kDa protein Smoothelin PF12510.3 ETO12049.1 - 8.1 6.3 9.6 1.9 8.3 0.1 3.3 3 1 1 4 4 4 0 Smoothelin cytoskeleton protein MMR_HSR1 PF01926.18 ETO12050.1 - 1e-05 25.4 2.2 0.00033 20.5 0.2 3.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.22 ETO12050.1 - 0.031 14.5 0.0 0.031 14.5 0.0 7.1 7 1 1 8 8 8 0 ABC transporter AAA_29 PF13555.1 ETO12050.1 - 0.071 12.6 0.1 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RVP PF00077.15 ETO12051.1 - 0.27 11.1 2.1 1.1 9.2 0.6 2.1 2 0 0 2 2 2 0 Retroviral aspartyl protease Peptidase_S49_N PF08496.5 ETO12051.1 - 2.1 8.1 10.2 0.89 9.3 4.6 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal WD40 PF00400.27 ETO12052.1 - 0.00017 21.3 0.0 0.0004 20.1 0.0 1.7 1 0 0 1 1 1 1 WD domain, G-beta repeat Acyl_transf_1 PF00698.16 ETO12055.1 - 1.6e-11 44.1 0.0 1.1e-06 28.2 0.0 2.7 1 1 1 2 2 2 2 Acyl transferase domain DUF3236 PF11576.3 ETO12055.1 - 0.36 10.2 9.6 0.15 11.4 2.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3236) Dynactin_p62 PF05502.8 ETO12056.1 - 1.6e-06 27.1 0.1 2.3e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Dynactin p62 family Nucleoplasmin PF03066.10 ETO12056.1 - 0.0019 17.7 4.2 0.0034 16.9 2.9 1.4 1 0 0 1 1 1 1 Nucleoplasmin Sporozoite_P67 PF05642.6 ETO12056.1 - 0.025 12.4 2.0 0.034 12.0 1.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sigma70_ner PF04546.8 ETO12056.1 - 0.47 10.0 6.1 0.96 9.0 4.2 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.5 ETO12056.1 - 5.1 7.3 11.8 11 6.3 8.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain WD40 PF00400.27 ETO12058.1 - 1.8e-13 49.7 9.0 1.2e-11 43.9 0.1 3.3 3 1 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO12058.1 - 3e-05 22.3 0.6 0.0018 16.5 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO12058.1 - 0.097 11.3 1.0 0.57 8.8 0.1 2.1 1 1 1 2 2 2 0 Nup133 N terminal like TPR_12 PF13424.1 ETO12059.1 - 4.9e-20 71.2 0.4 2.1e-09 37.1 0.9 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO12059.1 - 4.8e-13 48.1 13.0 1.5e-06 27.5 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO12059.1 - 3.9e-12 45.6 5.1 4.1e-05 23.1 0.0 2.8 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.1 ETO12059.1 - 2.6e-11 42.4 12.0 1.4e-06 27.6 1.9 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO12059.1 - 7.1e-08 31.7 11.2 0.00016 21.3 1.3 3.1 4 0 0 4 4 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO12059.1 - 1.6e-07 30.5 0.5 0.017 14.9 0.0 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO12059.1 - 5.2e-05 23.1 2.5 0.28 11.4 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO12059.1 - 0.00021 21.1 0.0 0.028 14.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO12059.1 - 0.00056 20.3 0.0 0.025 15.1 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Kelch_5 PF13854.1 ETO12059.1 - 0.003 17.4 0.5 0.044 13.7 0.0 3.0 3 0 0 3 3 3 1 Kelch motif TPR_16 PF13432.1 ETO12059.1 - 0.004 17.7 0.0 1.1 10.0 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO12059.1 - 0.014 15.5 3.9 0.33 11.1 1.3 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 ETO12059.1 - 0.03 14.1 1.4 4.1 7.3 0.1 2.9 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 ETO12059.1 - 0.036 14.5 6.2 0.3 11.6 1.0 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat Kelch_1 PF01344.20 ETO12059.1 - 0.14 11.7 2.1 1.2 8.7 0.1 3.4 4 0 0 4 4 4 0 Kelch motif LRR_6 PF13516.1 ETO12062.1 - 1.4e-08 33.9 21.4 0.00017 21.3 0.0 7.1 8 0 0 8 8 8 4 Leucine Rich repeat LRR_1 PF00560.28 ETO12062.1 - 9.2e-05 21.9 10.2 0.22 11.6 0.0 6.0 6 1 0 6 6 6 2 Leucine Rich Repeat LRR_8 PF13855.1 ETO12062.1 - 0.00016 21.3 11.0 0.011 15.4 0.1 4.4 3 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 ETO12062.1 - 0.0019 17.7 0.2 0.0019 17.7 0.2 4.8 2 2 4 6 6 6 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 ETO12062.1 - 1.1 9.7 12.2 11 6.7 0.0 5.3 6 0 0 6 6 6 0 Leucine rich repeat EamA PF00892.15 ETO12063.1 - 8.3e-15 54.9 34.5 3.8e-09 36.6 4.2 3.3 3 2 1 4 4 4 2 EamA-like transporter family EmrE PF13536.1 ETO12063.1 - 1.2e-11 44.7 24.6 2.1e-07 31.1 4.6 3.3 3 1 0 3 3 3 2 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 ETO12063.1 - 0.011 14.8 0.3 0.011 14.8 0.2 3.1 3 1 0 3 3 3 0 Nucleotide-sugar transporter PBP1_TM PF14812.1 ETO12063.1 - 0.038 14.3 9.5 0.3 11.4 0.8 2.9 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FLO_LFY PF01698.11 ETO12063.1 - 1.6 7.5 7.1 1.4 7.7 0.3 2.4 3 0 0 3 3 3 0 Floricaula / Leafy protein WI12 PF07107.6 ETO12064.1 - 0.11 12.4 0.1 0.5 10.2 0.0 1.9 2 0 0 2 2 2 0 Wound-induced protein WI12 GA PF01468.12 ETO12064.1 - 0.12 12.5 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 GA module DUF2262 PF10020.4 ETO12066.1 - 0.037 14.2 3.8 0.063 13.4 2.6 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2262) Colicin_V PF02674.11 ETO12067.1 - 0.0092 15.8 2.6 1.8 8.4 0.1 2.1 2 0 0 2 2 2 2 Colicin V production protein UPF0233 PF06781.7 ETO12067.1 - 0.013 15.1 1.1 1.9 8.1 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) Ctr PF04145.10 ETO12067.1 - 4.4 7.3 7.7 26 4.8 5.3 2.0 1 1 0 1 1 1 0 Ctr copper transporter family DUF2645 PF10840.3 ETO12068.1 - 0.0099 16.0 0.1 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2645) Osteopontin PF00865.13 ETO12068.1 - 0.011 15.0 6.3 0.018 14.2 4.3 1.3 1 0 0 1 1 1 0 Osteopontin GpcrRhopsn4 PF10192.4 ETO12068.1 - 0.011 14.8 0.1 0.017 14.3 0.1 1.2 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain Retinal PF15449.1 ETO12068.1 - 0.087 10.4 1.6 0.11 10.2 1.1 1.0 1 0 0 1 1 1 0 Retinal protein CaKB PF03185.10 ETO12069.1 - 0.2 10.9 5.2 0.39 10.0 3.6 1.4 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit Daxx PF03344.10 ETO12069.1 - 0.74 8.2 30.9 0.14 10.5 11.1 2.3 2 0 0 2 2 2 0 Daxx Family DUF3987 PF13148.1 ETO12069.1 - 2.5 6.5 10.0 0.049 12.1 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Merozoite_SPAM PF07133.6 ETO12070.1 - 0.019 14.8 5.5 0.037 13.9 3.8 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SPRY PF00622.23 ETO12070.1 - 0.07 13.2 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 SPRY domain Glyco_transf_49 PF13896.1 ETO12072.1 - 1.6e-12 47.1 0.1 2.7e-12 46.4 0.1 1.3 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 ETO12072.1 - 3.6e-06 26.2 0.0 4.8e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 ETO12072.1 - 0.0019 17.8 0.1 0.0033 17.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 WD40 PF00400.27 ETO12073.1 - 4.6e-57 187.9 17.6 1.1e-09 37.7 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO12073.1 - 5.9e-12 44.4 8.4 0.02 13.0 0.0 5.9 1 1 5 6 6 6 6 Nucleoporin Nup120/160 ELF PF03317.8 ETO12073.1 - 0.0037 16.6 3.6 0.0076 15.5 2.5 1.4 1 0 0 1 1 1 1 ELF protein WD40 PF00400.27 ETO12074.1 - 2.6e-176 566.0 63.7 9e-13 47.5 1.3 16.2 16 0 0 16 16 16 16 WD domain, G-beta repeat Pentapeptide PF00805.17 ETO12074.1 - 2.2e-06 26.7 0.8 4.3e-06 25.8 0.5 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Cytochrom_D1 PF02239.11 ETO12074.1 - 5.1e-05 21.7 6.5 0.9 7.7 0.2 5.2 4 2 2 6 6 6 3 Cytochrome D1 heme domain DUF1938 PF09153.5 ETO12074.1 - 8e-05 22.3 1.2 1.9 8.3 0.0 5.4 4 2 1 5 5 5 1 Domain of unknown function (DUF1938) Pentapeptide_4 PF13599.1 ETO12074.1 - 0.00014 21.5 0.5 0.00049 19.8 0.1 2.1 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) Mid2 PF04478.7 ETO12074.1 - 0.00039 19.8 27.3 2.6 7.4 0.0 9.8 5 2 7 12 12 12 3 Mid2 like cell wall stress sensor Pentapeptide_3 PF13576.1 ETO12074.1 - 0.006 16.4 1.5 0.025 14.4 0.0 2.9 3 0 0 3 3 3 1 Pentapeptide repeats (9 copies) NtA PF03146.10 ETO12074.1 - 0.98 9.0 4.2 13 5.3 0.0 4.8 5 2 1 6 6 6 0 Agrin NtA domain Mak10 PF04112.8 ETO12075.1 - 0.063 12.4 0.2 0.074 12.2 0.1 1.3 1 1 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase WD40 PF00400.27 ETO12076.1 - 1e-68 224.9 18.2 1.4e-11 43.7 0.4 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO12076.1 - 5.1e-13 48.0 2.7 0.001 17.3 0.1 5.7 2 2 3 6 6 6 5 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO12076.1 - 5.1e-06 26.7 4.1 5.1e-06 26.7 2.8 3.1 2 1 1 3 3 3 1 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 ETO12076.1 - 0.22 11.5 8.0 0.23 11.5 0.6 4.1 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF4220 PF13968.1 ETO12076.1 - 9.5 5.1 7.4 19 4.2 4.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4220) Peptidase_C14 PF00656.17 ETO12077.1 - 1.1e-10 41.6 1.5 1.1e-10 41.6 1.0 1.9 2 0 0 2 2 2 1 Caspase domain Kelch_4 PF13418.1 ETO12077.1 - 2.9e-06 26.9 0.3 0.014 15.1 0.0 3.5 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO12077.1 - 2.1e-05 24.5 1.6 0.84 9.9 0.1 4.4 3 1 1 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO12077.1 - 0.0004 20.2 0.0 0.018 15.0 0.1 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.20 ETO12077.1 - 0.0031 17.0 0.6 0.14 11.7 0.0 3.8 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 ETO12077.1 - 0.08 13.1 0.0 41 4.5 0.0 3.4 3 0 0 3 3 3 0 Galactose oxidase, central domain MCM_N PF14551.1 ETO12077.1 - 3.6 8.0 9.9 0.45 11.0 0.3 3.3 3 1 0 3 3 3 0 MCM N-terminal domain HMG_box_2 PF09011.5 ETO12078.1 - 9.7e-07 29.0 2.5 9.7e-07 29.0 1.8 3.3 2 1 1 3 3 3 1 HMG-box domain HMG_box PF00505.14 ETO12078.1 - 1.2e-06 28.6 0.8 1.2e-06 28.6 0.5 2.9 3 0 0 3 3 3 1 HMG (high mobility group) box SIMPL PF04402.9 ETO12079.1 - 0.15 11.9 0.1 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF541) FRG PF08867.6 ETO12080.1 - 0.035 14.6 0.1 0.042 14.3 0.1 1.3 1 0 0 1 1 1 0 FRG domain DUF1220 PF06758.8 ETO12080.1 - 0.12 12.1 0.3 4.4 7.1 0.0 2.4 2 1 1 3 3 3 0 Repeat of unknown function (DUF1220) Oxidored_q3 PF00499.15 ETO12081.1 - 0.019 14.7 0.2 0.027 14.2 0.1 1.3 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 ETRAMP PF09716.5 ETO12081.1 - 2 8.3 5.9 11 6.1 0.5 3.5 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) DUF1049 PF06305.6 ETO12082.1 - 0.059 12.8 1.6 0.15 11.5 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Bac_small_YrzI PF09501.5 ETO12083.1 - 0.13 12.1 0.4 0.13 12.1 0.3 2.1 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) Tetraspannin PF00335.15 ETO12085.1 - 1.5 8.0 8.3 0.073 12.3 1.4 1.9 2 0 0 2 2 2 0 Tetraspanin family SecA_DEAD PF07517.9 ETO12088.1 - 1.9e-08 33.9 0.0 3.6e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 SecA DEAD-like domain AAA PF00004.24 ETO12088.1 - 0.076 13.2 0.0 0.82 9.8 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Baculo_PEP_C PF04513.7 ETO12089.1 - 0.024 14.4 0.7 0.047 13.5 0.5 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HEAT_2 PF13646.1 ETO12092.1 - 2.6e-23 82.0 0.0 1.6e-05 25.0 0.0 7.4 5 2 2 7 7 7 6 HEAT repeats HEAT PF02985.17 ETO12092.1 - 1.8e-15 55.5 3.5 1.1 9.4 0.0 10.6 11 0 0 11 11 11 4 HEAT repeat Cnd1 PF12717.2 ETO12092.1 - 6.3e-10 39.1 32.4 1.4e-05 24.9 0.5 5.5 1 1 4 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 ETO12092.1 - 1.4e-08 34.9 0.0 0.58 10.7 0.0 8.0 7 4 3 10 10 9 1 HEAT-like repeat Ank_3 PF13606.1 ETO12092.1 - 1.4e-05 24.8 0.4 0.00026 20.9 0.0 3.5 4 0 0 4 4 3 1 Ankyrin repeat Arm PF00514.18 ETO12092.1 - 0.00039 20.1 0.2 29 4.7 0.0 5.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 ETO12092.1 - 0.00087 19.6 23.3 0.026 14.9 0.1 7.5 5 2 3 8 8 7 1 Vacuolar 14 Fab1-binding region Ank_2 PF12796.2 ETO12092.1 - 0.0012 19.1 0.3 0.011 16.0 0.0 2.9 3 0 0 3 3 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO12092.1 - 0.049 13.4 0.1 0.28 11.0 0.0 2.4 2 0 0 2 2 1 0 Ankyrin repeat Ank_5 PF13857.1 ETO12092.1 - 0.056 13.7 0.0 0.39 11.0 0.0 2.5 2 0 0 2 2 1 0 Ankyrin repeats (many copies) HEAT_PBS PF03130.11 ETO12092.1 - 0.14 12.6 0.1 2e+02 2.9 0.0 4.5 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat WD40 PF00400.27 ETO12094.1 - 1e-57 190.0 7.6 3.7e-12 45.6 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO12094.1 - 0.00022 19.6 0.0 0.0032 15.8 0.0 2.2 1 1 1 2 2 2 1 Cytochrome D1 heme domain PD40 PF07676.7 ETO12094.1 - 0.0058 16.2 6.4 27 4.5 0.0 5.0 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Kelch_6 PF13964.1 ETO12094.1 - 0.0059 16.7 0.4 0.4 10.9 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Nbas_N PF15492.1 ETO12094.1 - 0.024 13.7 0.1 7.5 5.5 0.0 2.6 1 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Me-amine-dh_H PF06433.6 ETO12094.1 - 0.056 12.0 0.0 0.19 10.3 0.0 1.9 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) Gmad1 PF10647.4 ETO12094.1 - 0.28 10.5 0.0 3.2 7.0 0.0 2.6 2 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain Kelch_1 PF01344.20 ETO12094.1 - 0.47 10.0 2.4 3.3 7.3 0.0 3.1 3 0 0 3 3 3 0 Kelch motif ABC_tran PF00005.22 ETO12095.1 - 2.9e-29 102.1 0.0 4.3e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 ETO12095.1 - 7.7e-09 35.0 0.0 1.2e-06 27.8 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETO12095.1 - 1.7e-06 28.2 0.0 0.024 14.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 ETO12095.1 - 0.0001 22.1 0.0 0.00018 21.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_10 PF12846.2 ETO12095.1 - 0.00015 21.2 0.0 0.013 14.9 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain AAA_22 PF13401.1 ETO12095.1 - 0.00017 21.7 0.1 0.0021 18.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETO12095.1 - 0.00034 20.6 0.1 0.003 17.5 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 ETO12095.1 - 0.00058 19.3 0.0 0.0015 18.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 ETO12095.1 - 0.0007 20.4 0.0 0.0021 18.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 ETO12095.1 - 0.0032 17.0 0.0 0.081 12.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 ETO12095.1 - 0.0094 15.6 0.0 0.023 14.4 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 ETO12095.1 - 0.014 15.5 0.0 2.8 8.1 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 ETO12095.1 - 0.02 14.0 0.0 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 ETO12095.1 - 0.03 14.6 0.2 0.12 12.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 ETO12095.1 - 0.037 13.7 0.1 0.51 10.1 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain MMR_HSR1 PF01926.18 ETO12095.1 - 0.04 13.8 0.0 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.7 ETO12095.1 - 0.059 13.0 0.0 0.6 9.7 0.0 2.2 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.7 ETO12095.1 - 0.062 12.3 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin SbcCD_C PF13558.1 ETO12095.1 - 0.065 13.1 0.5 0.38 10.7 0.4 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 ETO12095.1 - 0.091 12.4 0.0 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Septin PF00735.13 ETO12095.1 - 0.098 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Septin FtsK_SpoIIIE PF01580.13 ETO12095.1 - 0.13 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_membrane PF00664.18 ETO12096.1 - 2.6e-37 128.7 0.8 3.2e-37 128.4 0.6 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF2294 PF10057.4 ETO12096.1 - 0.075 12.6 0.1 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2294) KAP_NTPase PF07693.9 ETO12096.1 - 0.11 11.4 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain PRANC PF09372.5 ETO12098.1 - 0.51 10.3 6.9 0.7 9.9 1.3 2.2 1 1 0 2 2 2 0 PRANC domain Ras PF00071.17 ETO12100.1 - 5.2e-29 100.7 0.0 7.6e-19 67.6 0.0 3.3 2 1 1 3 3 3 3 Ras family Miro PF08477.8 ETO12100.1 - 1.1e-12 48.5 1.8 2e-09 37.9 0.0 3.5 3 1 0 3 3 3 1 Miro-like protein Arf PF00025.16 ETO12100.1 - 5e-05 22.6 0.0 0.002 17.3 0.0 2.4 1 1 0 1 1 1 1 ADP-ribosylation factor family DUF258 PF03193.11 ETO12100.1 - 0.0086 15.2 0.3 0.013 14.6 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 ETO12100.1 - 0.0098 14.9 0.1 0.0098 14.9 0.0 1.9 2 0 0 2 2 2 1 Septin PduV-EutP PF10662.4 ETO12100.1 - 0.013 15.0 0.0 0.029 13.8 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF463 PF04317.7 ETO12100.1 - 0.021 13.4 0.3 0.076 11.5 0.0 2.0 2 0 0 2 2 2 0 YcjX-like family, DUF463 AAA_16 PF13191.1 ETO12100.1 - 0.026 14.5 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 ETO12100.1 - 0.032 14.3 0.0 0.096 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 ETO12100.1 - 0.045 13.4 0.1 0.08 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.18 ETO12100.1 - 0.045 13.6 3.9 0.13 12.2 0.0 3.2 3 2 0 3 3 3 0 50S ribosome-binding GTPase Arch_ATPase PF01637.13 ETO12100.1 - 0.057 13.1 0.4 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase TT_ORF2 PF02957.10 ETO12100.1 - 0.067 13.9 1.3 0.14 12.8 0.9 1.5 1 0 0 1 1 1 0 TT viral ORF2 RNA_pol_Rpc4 PF05132.9 ETO12100.1 - 4.8 7.1 7.7 0.55 10.2 0.6 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 U-box PF04564.10 ETO12101.1 - 7.5e-12 45.0 0.2 2e-11 43.6 0.1 1.8 1 0 0 1 1 1 1 U-box domain F-box PF00646.28 ETO12101.1 - 0.006 16.2 0.8 0.015 14.9 0.6 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 ETO12101.1 - 0.019 14.6 0.9 0.019 14.6 0.6 2.0 2 0 0 2 2 2 0 F-box-like PolyA_pol PF01743.15 ETO12103.1 - 0.0033 17.6 2.9 0.0038 17.4 2.0 1.0 1 0 0 1 1 1 1 Poly A polymerase head domain Glucokinase PF02685.11 ETO12103.1 - 0.0079 15.0 1.2 0.0095 14.7 0.8 1.0 1 0 0 1 1 1 1 Glucokinase DUF1938 PF09153.5 ETO12103.1 - 0.11 12.3 0.6 0.19 11.5 0.2 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1938) EnY2 PF10163.4 ETO12103.1 - 0.4 10.6 5.9 4 7.4 4.1 2.0 1 1 0 1 1 1 0 Transcription factor e(y)2 KH_5 PF13184.1 ETO12103.1 - 0.42 10.4 4.8 5 7.0 0.3 2.2 2 0 0 2 2 2 0 NusA-like KH domain Fib_alpha PF08702.5 ETO12103.1 - 0.47 10.5 10.2 0.6 10.2 7.0 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Met_synt_B12 PF02965.12 ETO12104.1 - 0.12 11.5 1.5 0.12 11.5 0.1 1.7 2 0 0 2 2 2 0 Vitamin B12 dependent methionine synthase, activation domain Kelch_6 PF13964.1 ETO12105.1 - 1.1e-07 31.7 3.2 0.016 15.3 0.4 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 ETO12105.1 - 3.7e-07 29.6 5.2 0.00057 19.5 0.3 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO12105.1 - 1.9e-05 24.0 5.9 0.0025 17.2 1.4 4.2 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO12105.1 - 0.00019 21.0 0.1 0.79 9.5 0.0 2.9 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO12105.1 - 0.017 15.0 5.8 2.3 8.2 1.3 4.5 5 0 0 5 5 5 0 Kelch motif KorB PF08535.5 ETO12106.1 - 0.037 14.1 0.0 0.1 12.7 0.0 1.7 1 1 1 2 2 2 0 KorB domain zf-DNA_Pol PF08996.5 ETO12109.1 - 0.11 11.7 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger Med6 PF04934.9 ETO12110.1 - 0.0062 16.0 1.3 0.0097 15.4 0.9 1.4 1 0 0 1 1 1 1 MED6 mediator sub complex component PYST-C1 PF09690.5 ETO12110.1 - 0.01 15.4 3.6 0.01 15.4 2.5 2.2 3 0 0 3 3 3 0 Plasmodium yoelii subtelomeric region (PYST-C1) LAGLIDADG_3 PF14528.1 ETO12110.1 - 0.056 13.6 3.4 0.085 13.1 1.8 1.7 1 1 0 1 1 1 0 LAGLIDADG-like domain DUF2779 PF11074.3 ETO12110.1 - 0.15 12.1 3.1 0.19 11.7 2.2 1.5 1 1 0 1 1 1 0 Domain of unknown function(DUF2779) C1_2 PF03107.11 ETO12112.1 - 0.018 15.1 2.5 0.054 13.6 1.7 1.9 1 0 0 1 1 1 0 C1 domain Cas_CXXC_CXXC PF09706.5 ETO12112.1 - 0.023 14.8 6.1 1.4 9.1 0.1 3.1 1 1 2 3 3 3 0 CRISPR-associated protein (Cas_CXXC_CXXC) NinF PF05810.7 ETO12112.1 - 0.095 12.5 0.3 0.095 12.5 0.2 2.0 2 0 0 2 2 2 0 NinF protein zinc-ribbons_6 PF07191.7 ETO12112.1 - 2.5 7.9 6.2 1.1 9.1 1.9 2.2 2 1 0 2 2 2 0 zinc-ribbons EDR1 PF14381.1 ETO12113.1 - 0.014 14.9 0.1 0.017 14.7 0.0 1.1 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 Ubiq_cyt_C_chap PF03981.7 ETO12113.1 - 0.083 12.7 0.0 0.099 12.4 0.0 1.2 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone VWA_3 PF13768.1 ETO12113.1 - 0.091 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain FlaC_arch PF05377.6 ETO12114.1 - 0.012 15.4 14.6 1.1 9.2 0.5 4.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) LTD PF00932.14 ETO12114.1 - 0.042 13.9 0.2 0.32 11.0 0.0 2.1 2 0 0 2 2 2 0 Lamin Tail Domain HSBP1 PF06825.7 ETO12114.1 - 0.2 11.2 4.7 23 4.6 3.3 2.6 1 1 0 1 1 1 0 Heat shock factor binding protein 1 FliD_C PF07195.7 ETO12114.1 - 0.3 10.3 17.8 0.79 8.9 3.5 3.3 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 C-terminus Fib_alpha PF08702.5 ETO12114.1 - 1.6 8.8 21.8 0.024 14.7 6.1 3.1 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF972 PF06156.8 ETO12114.1 - 3.7 7.9 30.0 1 9.6 4.3 4.3 3 1 1 4 4 4 0 Protein of unknown function (DUF972) Pox_A_type_inc PF04508.7 ETO12114.1 - 4.4 7.3 10.4 10 6.1 0.1 4.6 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Reo_sigmaC PF04582.7 ETO12114.1 - 4.6 6.3 4.8 1.1 8.3 0.9 1.6 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Pox_polyA_pol_N PF12630.2 ETO12115.1 - 0.025 14.6 0.9 0.048 13.7 0.1 1.8 2 0 0 2 2 2 0 Poxvirus poly(A) polymerase N-terminal domain ABC1 PF03109.11 ETO12117.1 - 4.6e-18 65.3 0.0 5.2e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 ABC1 family DUF3947 PF13135.1 ETO12118.1 - 0.01 16.0 6.6 0.017 15.3 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) L_protein_N PF15518.1 ETO12119.1 - 0.016 14.6 0.5 0.018 14.4 0.4 1.1 1 0 0 1 1 1 0 L protein N-terminus DUF562 PF04763.7 ETO12120.1 - 0.01 15.0 0.1 0.023 13.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF562) R3H PF01424.17 ETO12121.1 - 2.9e-05 23.6 0.0 8.2e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 R3H domain Vps52 PF04129.7 ETO12123.1 - 1.3e-23 83.3 2.6 1.6e-23 83.0 1.8 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family NACHT PF05729.7 ETO12123.1 - 0.14 11.7 0.2 0.28 10.8 0.2 1.5 1 1 0 1 1 1 0 NACHT domain Beach PF02138.13 ETO12124.1 - 1.3e-26 93.7 0.1 1.3e-26 93.7 0.1 2.2 2 1 0 2 2 2 1 Beige/BEACH domain TPR_11 PF13414.1 ETO12124.1 - 1.3e-22 79.1 18.4 2.4e-12 46.3 1.1 3.6 2 1 2 4 4 4 3 TPR repeat TPR_17 PF13431.1 ETO12124.1 - 3.2e-13 48.7 10.7 0.00077 19.4 0.1 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO12124.1 - 6.2e-12 44.5 15.1 0.0032 17.0 0.1 5.0 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO12124.1 - 2.2e-11 44.0 1.1 0.00037 21.0 0.0 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO12124.1 - 3.6e-10 38.9 15.7 0.022 14.6 0.4 5.5 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO12124.1 - 2.6e-08 33.7 0.1 0.81 10.5 0.0 4.7 3 2 2 5 5 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO12124.1 - 1.2e-07 31.0 14.8 0.14 11.9 0.2 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.1 ETO12124.1 - 2.1e-06 27.9 6.6 0.12 12.7 1.1 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO12124.1 - 9.5e-06 25.4 14.7 0.013 15.4 2.3 3.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO12124.1 - 0.05 13.4 5.1 17 5.5 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat FAT PF02259.18 ETO12124.1 - 0.15 10.9 9.6 0.13 11.2 0.5 2.3 1 1 0 2 2 2 0 FAT domain DUF1048 PF06304.6 ETO12124.1 - 0.53 10.6 5.4 1.6 9.0 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1048) Fib_succ_major PF09603.5 ETO12126.1 - 0.055 13.9 1.2 0.066 13.7 0.8 1.1 1 0 0 1 1 1 0 Fibrobacter succinogenes major domain (Fib_succ_major) RE_NgoPII PF09521.5 ETO12126.1 - 0.064 12.0 0.7 0.078 11.7 0.5 1.1 1 0 0 1 1 1 0 NgoPII restriction endonuclease Ribosomal_S2 PF00318.15 ETO12127.1 - 0.019 14.1 0.4 0.049 12.8 0.3 1.7 1 0 0 1 1 1 0 Ribosomal protein S2 Catalase-rel PF06628.7 ETO12127.1 - 0.18 11.6 1.1 4.8 7.1 0.2 2.5 1 1 1 2 2 2 0 Catalase-related immune-responsive F-box-like PF12937.2 ETO12127.1 - 0.77 9.5 0.0 0.77 9.5 0.0 2.9 3 0 0 3 3 3 0 F-box-like Secretin_N_2 PF07655.8 ETO12129.1 - 2.7 8.4 35.7 0.69 10.3 8.0 3.9 3 0 0 3 3 3 0 Secretin N-terminal domain WD40 PF00400.27 ETO12130.1 - 1.6e-89 290.9 23.5 1.9e-13 49.6 0.3 7.8 8 0 0 8 8 8 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO12130.1 - 3.3e-06 26.1 9.1 0.19 10.4 0.1 4.7 1 1 3 5 5 5 3 Nup133 N terminal like PD40 PF07676.7 ETO12130.1 - 8.4e-06 25.3 9.0 2 8.1 0.0 6.4 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat Gmad1 PF10647.4 ETO12130.1 - 2.3e-05 23.9 0.1 0.038 13.3 0.0 3.6 1 1 2 3 3 3 2 Lipoprotein LpqB beta-propeller domain Cytochrom_D1 PF02239.11 ETO12130.1 - 2.7e-05 22.6 0.6 1.1 7.4 0.0 3.5 1 1 0 3 3 3 3 Cytochrome D1 heme domain DUF1652 PF07865.6 ETO12130.1 - 0.0021 17.6 0.0 6.3 6.4 0.0 4.4 2 1 2 4 4 4 1 Protein of unknown function (DUF1652) MMS1_N PF10433.4 ETO12130.1 - 0.0095 14.1 0.0 0.77 7.8 0.0 3.3 1 1 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term PQQ_2 PF13360.1 ETO12130.1 - 0.015 14.7 0.1 0.042 13.2 0.1 1.8 1 1 0 1 1 1 0 PQQ-like domain Resistin PF06954.6 ETO12130.1 - 0.02 15.1 6.1 30 4.9 0.2 5.3 2 2 3 5 5 5 0 Resistin NodS PF05401.6 ETO12130.1 - 0.022 14.1 0.2 2.3 7.5 0.0 3.5 2 1 0 3 3 3 0 Nodulation protein S (NodS) Me-amine-dh_H PF06433.6 ETO12130.1 - 0.033 12.8 0.0 2 6.9 0.0 2.5 2 1 0 3 3 3 0 Methylamine dehydrogenase heavy chain (MADH) DUF1258 PF06869.7 ETO12130.1 - 0.21 10.6 5.0 1.5 7.8 0.2 3.5 1 1 3 5 5 5 0 Protein of unknown function (DUF1258) Proteasome_A_N PF10584.4 ETO12130.1 - 3.6 6.9 11.1 53 3.2 0.0 5.1 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature ACBP PF00887.14 ETO12131.1 - 4.1e-17 61.6 0.4 1.1e-10 41.0 0.0 2.5 3 0 0 3 3 3 2 Acyl CoA binding protein Gly-zipper_YMGG PF13441.1 ETO12132.1 - 4.8 6.7 8.8 2.1e+02 1.5 6.1 2.5 1 1 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.1 ETO12132.1 - 6.5 6.4 9.9 8 6.1 0.6 2.8 2 1 0 2 2 2 0 Glycine zipper WD40 PF00400.27 ETO12133.1 - 9.6e-14 50.6 4.3 1.7e-05 24.4 0.0 6.4 7 0 0 7 7 7 2 WD domain, G-beta repeat PD40 PF07676.7 ETO12133.1 - 0.36 10.5 6.2 22 4.8 0.0 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Lipocalin_4 PF13648.1 ETO12133.1 - 3 8.5 8.8 2.4 8.7 4.2 2.4 2 1 1 3 3 3 0 Lipocalin-like domain NACHT PF05729.7 ETO12134.1 - 1.2e-07 31.5 0.0 2.6e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETO12134.1 - 0.0002 21.4 0.0 0.00057 20.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 ETO12134.1 - 0.045 13.6 1.0 0.17 11.8 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 ETO12134.1 - 0.051 13.5 0.2 0.69 9.8 0.1 2.4 1 1 0 1 1 1 0 AAA ATPase domain GAGA_bind PF06217.7 ETO12135.1 - 0.13 12.2 7.7 0.15 12.0 5.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RPOL_N PF14700.1 ETO12135.1 - 0.56 9.4 8.2 0.78 8.9 5.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal PMSI1 PF15322.1 ETO12135.1 - 2.7 6.9 7.9 3.6 6.5 5.5 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative HEAT_2 PF13646.1 ETO12136.1 - 6.1e-06 26.4 0.0 3.7e-05 23.9 0.0 2.3 1 1 1 2 2 2 1 HEAT repeats HEAT PF02985.17 ETO12136.1 - 1e-05 25.1 0.4 0.073 13.1 0.0 2.9 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.1 ETO12136.1 - 0.0018 18.7 0.0 0.062 13.8 0.0 2.6 2 1 1 3 3 3 2 HEAT-like repeat DUF2435 PF10363.4 ETO12136.1 - 0.053 13.4 1.7 0.17 11.7 0.2 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2435) DNA_pol3_gamma3 PF12169.3 ETO12136.1 - 0.076 12.7 0.1 3.1 7.5 0.0 2.6 1 1 1 2 2 2 0 DNA polymerase III subunits gamma and tau domain III DALR_1 PF05746.10 ETO12136.1 - 0.19 11.7 3.3 0.45 10.4 0.4 2.0 1 1 1 2 2 2 0 DALR anticodon binding domain Ank_2 PF12796.2 ETO12137.1 - 1.4e-09 38.1 0.5 1.1e-08 35.3 0.1 2.5 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO12137.1 - 2.3e-07 30.3 0.2 0.0021 18.1 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 ETO12137.1 - 6.8e-06 25.6 0.1 0.0061 16.3 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 ETO12137.1 - 2.3e-05 24.7 0.2 7.3e-05 23.1 0.2 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO12137.1 - 3.3e-05 23.9 1.0 0.0059 16.8 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) WD40 PF00400.27 ETO12138.1 - 2.1e-30 103.5 4.9 2.4e-15 55.7 0.2 3.8 3 1 1 4 4 4 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO12138.1 - 0.0001 21.2 1.1 0.053 12.2 0.1 2.1 1 1 1 2 2 2 2 Nup133 N terminal like RVT_thumb PF06817.9 ETO12138.1 - 0.0085 15.6 0.1 1.9 8.0 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase thumb domain Resistin PF06954.6 ETO12138.1 - 0.0097 16.1 0.0 1.7 8.9 0.0 2.1 1 1 1 2 2 2 1 Resistin Nup160 PF11715.3 ETO12138.1 - 0.012 13.7 0.4 1.8 6.6 0.0 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 PD40 PF07676.7 ETO12138.1 - 0.023 14.3 2.4 1.5 8.6 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF1914 PF08932.5 ETO12138.1 - 0.038 14.0 0.6 2.5 8.1 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1914) Cytochrom_D1 PF02239.11 ETO12138.1 - 0.044 12.0 0.0 0.054 11.7 0.0 1.1 1 0 0 1 1 1 0 Cytochrome D1 heme domain 3HCDH_N PF02737.13 ETO12139.1 - 1.7e-20 73.4 0.3 3.3e-13 49.6 0.0 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 ETO12139.1 - 2.8e-19 69.3 0.3 1.5e-15 57.3 0.2 2.8 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Ras PF00071.17 ETO12140.1 - 5.2e-19 68.2 0.0 7.5e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO12140.1 - 8.8e-05 22.9 0.0 0.0002 21.8 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein WD40 PF00400.27 ETO12141.1 - 9.3e-27 91.9 1.5 1.1e-13 50.4 0.1 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat PD40 PF07676.7 ETO12141.1 - 0.009 15.6 0.1 5.8 6.6 0.0 2.5 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Gmad1 PF10647.4 ETO12141.1 - 0.012 14.9 0.0 4.6 6.5 0.0 2.6 3 0 0 3 3 3 0 Lipoprotein LpqB beta-propeller domain eIF2A PF08662.6 ETO12141.1 - 0.074 12.7 0.0 0.099 12.3 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Rpn3_C PF08375.6 ETO12141.1 - 0.15 12.4 0.0 21 5.5 0.0 2.8 3 0 0 3 3 3 0 Proteasome regulatory subunit C-terminal Cas_Cas02710 PF09670.5 ETO12143.1 - 0.041 12.5 0.0 0.053 12.1 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) Xpo1 PF08389.7 ETO12144.1 - 1.3e-29 103.0 2.3 5.5e-29 100.9 0.8 2.0 2 0 0 2 2 2 1 Exportin 1-like protein DUF3962 PF13111.1 ETO12144.1 - 0.02 14.2 2.9 0.032 13.6 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3962) DUF3796 PF12676.2 ETO12144.1 - 0.29 11.3 7.4 0.41 10.8 4.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3796) RRM_6 PF14259.1 ETO12145.1 - 1e-06 28.5 0.1 2e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO12145.1 - 6.9e-05 22.4 0.1 0.00029 20.4 0.1 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO12145.1 - 0.058 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sbi-IV PF11621.3 ETO12145.1 - 0.22 11.7 2.9 0.38 10.9 1.5 1.9 1 1 1 2 2 2 0 C3 binding domain 4 of IgG-bind protein SBI DUF3586 PF12131.3 ETO12147.1 - 0.03 14.3 9.3 0.096 12.7 1.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3586) B_lectin PF01453.19 ETO12147.1 - 0.055 13.3 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 D-mannose binding lectin ETF_QO PF05187.8 ETO12148.1 - 2.9e-33 114.1 0.1 6e-33 113.1 0.1 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 ETO12148.1 - 5.8e-11 41.8 0.6 7.7e-06 25.0 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETO12148.1 - 7.8e-09 34.8 1.0 4.5e-06 25.7 1.0 2.2 1 1 1 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 ETO12148.1 - 1.5e-06 28.1 0.0 5e-06 26.4 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETO12148.1 - 2.8e-06 27.3 0.0 8.6e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETO12148.1 - 3.3e-06 26.9 0.0 8.4e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.12 ETO12148.1 - 1e-05 24.7 0.0 1e-05 24.7 0.0 2.5 3 0 0 3 3 2 2 Thi4 family HI0933_like PF03486.9 ETO12148.1 - 1.1e-05 24.1 0.0 2.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 ETO12148.1 - 1.8e-05 24.9 0.0 4.2e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETO12148.1 - 8e-05 21.7 0.3 0.00012 21.0 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 ETO12148.1 - 0.00052 19.1 0.2 0.0012 18.0 0.2 1.6 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 ETO12148.1 - 0.0012 17.9 0.0 0.0018 17.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 ETO12148.1 - 0.0022 16.7 1.5 0.0046 15.6 0.4 1.8 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.22 ETO12148.1 - 0.0077 16.6 0.1 0.28 11.6 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.2 ETO12148.1 - 0.014 15.7 3.5 0.02 15.2 0.6 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain DUF4066 PF13278.1 ETO12148.1 - 0.03 13.5 0.0 0.062 12.5 0.0 1.5 1 0 0 1 1 1 0 Putative amidotransferase GIDA PF01134.17 ETO12148.1 - 0.042 12.7 0.0 0.077 11.8 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_2 PF12797.2 ETO12148.1 - 0.043 13.7 0.6 0.11 12.4 0.4 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_6 PF12837.2 ETO12148.1 - 3.3 7.7 5.6 0.54 10.2 0.7 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain SNARE_assoc PF09335.6 ETO12149.1 - 0.15 12.2 4.3 0.42 10.8 0.1 2.2 2 0 0 2 2 2 0 SNARE associated Golgi protein TFIIA PF03153.8 ETO12150.1 - 3.2e-05 24.0 30.4 3.2e-05 24.0 21.0 2.0 1 1 1 2 2 2 1 Transcription factor IIA, alpha/beta subunit PPP4R2 PF09184.6 ETO12150.1 - 0.00015 21.4 10.0 0.00015 21.4 6.9 3.2 3 0 0 3 3 3 2 PPP4R2 HNOBA PF07701.9 ETO12150.1 - 0.0084 15.3 2.1 0.0084 15.3 1.4 2.7 2 1 0 2 2 2 1 Heme NO binding associated SSP160 PF06933.6 ETO12150.1 - 0.017 13.1 6.0 0.029 12.3 4.2 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Prothymosin PF03247.9 ETO12150.1 - 0.25 11.5 58.7 0.027 14.6 14.6 3.3 3 0 0 3 3 3 0 Prothymosin/parathymosin family Methyltransf_12 PF08242.7 ETO12150.1 - 0.32 11.5 0.1 0.32 11.5 0.1 3.0 4 0 0 4 4 4 0 Methyltransferase domain DUF912 PF06024.7 ETO12150.1 - 0.84 9.7 0.0 0.84 9.7 0.0 4.8 5 1 1 6 6 6 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Daxx PF03344.10 ETO12150.1 - 9.1 4.6 44.0 0.14 10.6 3.7 2.5 2 1 0 2 2 2 0 Daxx Family Lipase_3 PF01764.20 ETO12151.1 - 1.7e-11 43.9 0.0 2.3e-09 36.9 0.0 2.6 2 0 0 2 2 2 2 Lipase (class 3) Moulting_cycle PF04870.11 ETO12152.1 - 0.0059 15.7 0.7 0.0072 15.4 0.5 1.1 1 0 0 1 1 1 1 Moulting cycle DinB_2 PF12867.2 ETO12152.1 - 0.085 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 DinB superfamily DUF2457 PF10446.4 ETO12153.1 - 0.028 13.1 13.3 0.024 13.3 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) ERM PF00769.14 ETO12153.1 - 0.16 11.5 3.2 0.16 11.4 2.3 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Nop14 PF04147.7 ETO12153.1 - 0.36 8.7 10.3 0.33 8.8 7.1 1.0 1 0 0 1 1 1 0 Nop14-like family Med13_C PF06333.7 ETO12153.1 - 0.57 8.6 3.9 0.61 8.5 2.7 1.0 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal NOA36 PF06524.7 ETO12153.1 - 0.87 8.7 12.3 0.84 8.8 8.5 1.2 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 ETO12153.1 - 0.91 7.4 5.8 0.89 7.5 4.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 ETO12153.1 - 1.1 8.7 6.3 1.3 8.5 4.3 1.2 1 0 0 1 1 1 0 Nucleoplasmin CobT PF06213.7 ETO12153.1 - 1.4 7.9 8.3 1.4 7.9 5.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Tom22 PF04281.8 ETO12153.1 - 1.5 8.3 4.5 2.2 7.8 3.1 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Sporozoite_P67 PF05642.6 ETO12153.1 - 1.5 6.5 5.7 1.5 6.6 3.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Herpes_LMP1 PF05297.6 ETO12153.1 - 3.5 6.4 19.6 3.8 6.3 13.6 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Secretin_N_2 PF07655.8 ETO12153.1 - 6.6 7.1 11.2 11 6.4 7.8 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain SAGA-Tad1 PF12767.2 ETO12154.1 - 0.0087 15.7 1.3 0.0087 15.7 0.9 1.6 1 1 1 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit Peptidase_U49 PF10463.4 ETO12154.1 - 0.038 13.7 0.5 0.1 12.3 0.1 1.8 1 1 1 2 2 2 0 Peptidase U49 Kelch_1 PF01344.20 ETO12155.1 - 2e-08 33.6 0.7 3.7e-06 26.3 0.4 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.1 ETO12155.1 - 1.5e-05 24.9 0.9 0.0048 17.0 0.3 2.4 1 1 1 2 2 2 2 Kelch motif Kelch_4 PF13418.1 ETO12155.1 - 3.2e-05 23.5 0.2 0.052 13.3 0.1 2.5 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO12155.1 - 0.0001 21.9 0.6 0.021 14.6 0.3 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.1 ETO12155.1 - 0.00014 21.7 1.3 0.0092 15.9 0.2 2.7 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 ETO12155.1 - 0.00067 19.7 0.0 0.0051 16.9 0.0 2.2 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO12156.1 - 6.5e-05 22.6 0.2 0.02 14.6 0.0 3.4 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO12156.1 - 0.0002 20.8 2.0 0.026 14.0 0.4 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO12156.1 - 0.0033 17.1 2.4 0.17 11.6 0.3 3.6 3 1 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 ETO12156.1 - 0.0077 16.3 4.5 3.4 8.0 0.0 3.7 3 1 1 4 4 4 2 Kelch motif Peptidase_C14 PF00656.17 ETO12158.1 - 1.9e-08 34.2 0.9 4.5e-08 33.0 0.6 1.6 1 0 0 1 1 1 1 Caspase domain DUF4363 PF14276.1 ETO12158.1 - 0.00012 21.8 7.3 0.00012 21.8 5.1 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4363) Det1 PF09737.4 ETO12159.1 - 0.0073 15.1 0.0 0.0094 14.7 0.0 1.2 1 0 0 1 1 1 1 De-etiolated protein 1 Det1 FACT-Spt16_Nlob PF14826.1 ETO12159.1 - 0.093 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 FACT complex subunit SPT16 N-terminal lobe domain Daxx PF03344.10 ETO12161.1 - 0.096 11.1 0.0 0.15 10.5 0.0 1.2 1 0 0 1 1 1 0 Daxx Family TH1 PF04858.8 ETO12163.1 - 1.9e-06 26.3 0.5 2.4e-06 26.0 0.4 1.1 1 0 0 1 1 1 1 TH1 protein Borrelia_REV PF03978.8 ETO12163.1 - 0.57 9.8 7.1 0.12 12.0 2.6 1.5 2 0 0 2 2 2 0 Borrelia burgdorferi REV protein PrgI PF12666.2 ETO12164.1 - 0.1 12.7 0.1 0.1 12.7 0.1 2.9 2 1 1 3 3 3 0 PrgI family protein HlyIII PF03006.15 ETO12164.1 - 0.38 10.1 13.6 1.4 8.3 9.4 1.8 1 1 0 1 1 1 0 Haemolysin-III related ABC2_membrane_5 PF13346.1 ETO12164.1 - 2.6 7.2 20.8 0.093 12.0 5.2 2.7 3 0 0 3 3 3 0 ABC-2 family transporter protein DUF805 PF05656.9 ETO12164.1 - 4.6 7.1 9.9 1.5 8.6 0.4 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF805) Pex14_N PF04695.8 ETO12165.1 - 1.8 8.6 10.1 0.68 9.9 2.5 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region WD40 PF00400.27 ETO12166.1 - 1.3e-11 43.8 0.1 0.00032 20.4 0.0 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO12166.1 - 0.085 11.5 0.1 4.1 6.0 0.0 2.0 1 1 1 2 2 2 0 Nup133 N terminal like NDUF_B8 PF05821.6 ETO12168.1 - 0.07 12.7 0.3 0.083 12.5 0.2 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) TnpV PF14198.1 ETO12168.1 - 0.12 12.2 0.1 0.25 11.2 0.0 1.6 1 1 0 1 1 1 0 Transposon-encoded protein TnpV GATase PF00117.23 ETO12169.1 - 1.6e-05 24.4 0.0 2.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 ETO12169.1 - 0.0067 15.8 0.0 0.0094 15.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase C26 MHCassoc_trimer PF08831.5 ETO12169.1 - 0.07 12.9 0.3 0.27 11.0 0.2 1.9 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain NACHT PF05729.7 ETO12170.1 - 8.9e-10 38.4 0.0 1.9e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO12170.1 - 8.2e-06 26.1 0.1 3.9e-05 23.9 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ETO12170.1 - 0.00025 21.1 0.0 0.0021 18.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ETO12170.1 - 0.0012 19.6 0.0 0.009 16.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain RelA_SpoT PF04607.12 ETO12170.1 - 0.0037 17.2 3.0 0.0054 16.7 0.5 2.5 2 0 0 2 2 2 1 Region found in RelA / SpoT proteins UPF0079 PF02367.12 ETO12170.1 - 0.026 14.1 0.0 0.17 11.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 ETO12170.1 - 0.042 12.9 0.0 0.097 11.7 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin KaiC PF06745.8 ETO12170.1 - 0.043 12.9 0.5 0.34 9.9 0.0 2.4 2 1 0 2 2 2 0 KaiC RNA_helicase PF00910.17 ETO12170.1 - 0.044 13.9 1.8 0.32 11.1 0.0 3.1 2 2 0 2 2 2 0 RNA helicase ABC_tran PF00005.22 ETO12170.1 - 0.046 14.0 0.0 0.17 12.1 0.0 2.0 1 0 0 1 1 1 0 ABC transporter T2SE PF00437.15 ETO12170.1 - 0.052 12.4 0.0 0.19 10.6 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 ETO12170.1 - 0.076 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 ETO12170.1 - 0.11 12.0 0.0 0.3 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain A2L_zn_ribbon PF08792.5 ETO12170.1 - 0.37 10.3 4.2 0.24 10.9 1.0 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-LITAF-like PF10601.4 ETO12171.1 - 0.026 14.3 0.1 0.049 13.4 0.1 1.4 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain zf-H2C2_2 PF13465.1 ETO12171.1 - 0.047 13.9 1.3 0.06 13.6 0.1 1.8 2 0 0 2 2 2 0 Zinc-finger double domain Ogr_Delta PF04606.7 ETO12171.1 - 0.076 12.6 0.3 0.28 10.8 0.2 2.0 1 1 0 1 1 1 0 Ogr/Delta-like zinc finger A2L_zn_ribbon PF08792.5 ETO12171.1 - 0.085 12.3 1.7 0.1 12.0 0.1 2.0 2 0 0 2 2 2 0 A2L zinc ribbon domain Cas_CXXC_CXXC PF09706.5 ETO12171.1 - 0.12 12.5 0.3 0.4 10.8 0.1 1.9 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) DUF223 PF02721.9 ETO12171.1 - 0.14 12.2 0.3 0.58 10.2 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function DUF223 Kelch_6 PF13964.1 ETO12174.1 - 7.5e-06 25.8 0.5 0.011 15.9 0.0 3.7 2 1 1 3 3 3 1 Kelch motif Kelch_1 PF01344.20 ETO12174.1 - 8.7e-06 25.1 1.8 0.00071 19.0 0.0 3.2 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETO12174.1 - 0.0024 17.6 1.1 0.34 10.7 0.1 3.2 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO12174.1 - 0.018 15.1 0.0 0.076 13.2 0.0 2.1 1 0 0 1 1 1 0 Galactose oxidase, central domain Menin PF05053.8 ETO12174.1 - 1.3 7.0 7.2 2.3 6.2 5.0 1.3 1 0 0 1 1 1 0 Menin CENP-K PF11802.3 ETO12175.1 - 0.0099 15.1 0.7 0.014 14.6 0.5 1.2 1 0 0 1 1 1 1 Centromere-associated protein K Neur_chan_memb PF02932.11 ETO12177.1 - 6 6.6 6.3 1.6 8.5 1.8 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Med19 PF10278.4 ETO12179.1 - 0.015 15.0 3.0 0.015 15.0 2.1 1.7 1 1 1 2 2 2 0 Mediator of RNA pol II transcription subunit 19 DUF3464 PF11947.3 ETO12179.1 - 0.13 11.7 1.3 0.2 11.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) ELMO_CED12 PF04727.8 ETO12183.1 - 1.5e-24 86.4 4.1 2.7e-24 85.6 2.9 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family Eno-Rase_FAD_bd PF07055.7 ETO12183.1 - 0.05 13.5 0.3 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 Enoyl reductase FAD binding domain PDZ_2 PF13180.1 ETO12184.1 - 1e-06 28.5 0.2 2.7e-06 27.1 0.1 1.8 1 1 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.1 ETO12184.1 - 3.7e-06 26.9 0.0 1.1e-05 25.4 0.0 1.8 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.21 ETO12184.1 - 0.0088 15.6 0.7 0.014 14.9 0.0 1.7 2 0 0 2 2 2 1 Trypsin Codanin-1_C PF15296.1 ETO12184.1 - 0.022 14.6 1.2 0.052 13.3 0.9 1.6 1 0 0 1 1 1 0 Codanin-1 C-terminus Peptidase_S29 PF02907.10 ETO12184.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Peptidase_S55 PF05580.7 ETO12184.1 - 0.069 12.5 0.1 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 SpoIVB peptidase S55 PDZ PF00595.19 ETO12184.1 - 0.12 12.5 0.0 0.51 10.5 0.0 2.0 2 0 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) Aminotran_1_2 PF00155.16 ETO12185.1 - 6.9e-34 117.3 0.1 8.5e-34 117.0 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 ETO12185.1 - 2.1e-05 23.4 0.0 2.5e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 ETO12185.1 - 7.2e-05 21.2 0.0 0.00011 20.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme ATPase-cat_bd PF12156.3 ETO12185.1 - 0.063 13.8 1.6 0.14 12.6 0.2 2.2 2 1 0 2 2 2 0 Putative metal-binding domain of cation transport ATPase Aminotran_MocR PF12897.2 ETO12185.1 - 0.067 11.7 0.0 0.082 11.4 0.0 1.1 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Med27 PF11571.3 ETO12186.1 - 3.7e-05 23.7 2.7 0.00011 22.2 0.6 2.7 1 1 1 2 2 2 1 Mediator complex subunit 27 RGS PF00615.14 ETO12188.1 - 4.2e-11 42.9 1.0 1.1e-10 41.6 0.7 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain Tom37_C PF11801.3 ETO12188.1 - 3.5 7.4 14.8 0.071 12.9 3.1 2.6 1 1 1 2 2 2 0 Tom37 C-terminal domain DUF1776 PF08643.5 ETO12189.1 - 0.01 14.9 0.6 0.027 13.6 0.0 1.9 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) HNF-1_N PF04814.8 ETO12189.1 - 0.093 12.8 0.1 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus PA PF02225.17 ETO12190.1 - 0.0003 20.4 0.0 0.00057 19.5 0.0 1.4 1 0 0 1 1 1 1 PA domain YajC PF02699.10 ETO12190.1 - 0.099 12.3 0.4 0.17 11.5 0.3 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit Thr_synth_N PF14821.1 ETO12191.1 - 3.4e-23 81.4 0.0 6.2e-23 80.6 0.0 1.4 1 0 0 1 1 1 1 Threonine synthase N terminus DUF2465 PF10239.4 ETO12192.1 - 4.6e-33 114.7 0.0 9.9e-33 113.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2465) Trypan_PARP PF05887.6 ETO12192.1 - 2.4 7.9 23.5 2.7 7.7 15.4 1.6 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Daxx PF03344.10 ETO12192.1 - 3.9 5.8 13.8 5.6 5.3 9.5 1.1 1 0 0 1 1 1 0 Daxx Family IBR PF01485.16 ETO12193.1 - 3.1e-08 33.3 15.3 0.00035 20.4 2.1 2.3 2 0 0 2 2 2 2 IBR domain DUF839 PF05787.8 ETO12193.1 - 0.026 13.4 0.6 0.04 12.8 0.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF839) DZR PF12773.2 ETO12193.1 - 1.4 8.7 15.0 2 8.2 0.4 3.0 1 1 1 2 2 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 ETO12193.1 - 6.6 6.3 7.9 23 4.6 0.0 3.3 3 0 0 3 3 3 0 zinc-ribbon domain Transcrip_act PF04949.8 ETO12194.1 - 0.0014 18.2 12.8 0.0037 16.9 8.9 1.9 1 1 0 1 1 1 1 Transcriptional activator Herpes_UL25 PF01499.11 ETO12194.1 - 0.0036 15.6 3.5 0.0051 15.1 2.4 1.2 1 0 0 1 1 1 1 Herpesvirus UL25 family DUF3373 PF11853.3 ETO12194.1 - 0.27 9.7 5.5 0.44 9.0 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF4140 PF13600.1 ETO12194.1 - 3.3 8.1 9.0 1 9.8 2.0 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) PPR_2 PF13041.1 ETO12195.1 - 8.3e-05 22.4 0.3 0.00077 19.3 0.2 2.5 2 0 0 2 2 2 1 PPR repeat family PPR PF01535.15 ETO12195.1 - 0.00034 20.3 1.5 1.4 9.1 0.0 4.4 4 0 0 4 4 4 1 PPR repeat PPR_3 PF13812.1 ETO12195.1 - 0.00044 20.3 2.9 8.3 6.9 0.0 4.9 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 ETO12195.1 - 0.076 12.5 0.9 15 5.1 0.0 3.0 3 0 0 3 3 3 0 PPR repeat Ras PF00071.17 ETO12196.1 - 8.2e-16 57.8 0.0 4.2e-14 52.2 0.0 2.9 1 1 0 1 1 1 1 Ras family PAH PF02671.16 ETO12196.1 - 0.044 13.3 0.5 0.091 12.3 0.4 1.5 1 0 0 1 1 1 0 Paired amphipathic helix repeat Tafi-CsgC PF10610.4 ETO12196.1 - 0.089 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Thin aggregative fimbriae synthesis protein DUF3040 PF11239.3 ETO12197.1 - 0.47 10.5 3.2 0.55 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) zf-CCHC PF00098.18 ETO12199.1 - 0.00012 21.8 4.2 0.00012 21.8 2.9 1.9 2 0 0 2 2 2 1 Zinc knuckle RVP PF00077.15 ETO12199.1 - 0.00019 21.2 0.2 0.00086 19.1 0.0 2.2 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 ETO12199.1 - 0.029 14.8 0.0 0.086 13.3 0.0 1.8 1 1 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.1 ETO12199.1 - 0.17 11.7 0.0 24 4.8 0.0 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease TPR_12 PF13424.1 ETO12200.1 - 2.6e-90 296.4 20.3 3.8e-18 65.1 0.3 6.6 2 2 3 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.23 ETO12200.1 - 2.5e-59 194.5 56.5 9.1e-08 31.3 1.1 10.9 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_11 PF13414.1 ETO12200.1 - 4.3e-57 189.6 36.2 1.7e-17 62.7 1.8 7.0 5 2 2 7 7 7 6 TPR repeat TPR_2 PF07719.12 ETO12200.1 - 5.9e-49 160.0 34.8 1.4e-06 27.7 0.3 10.5 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_10 PF13374.1 ETO12200.1 - 9e-43 143.0 0.0 2.3e-05 24.1 0.0 9.4 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_7 PF13176.1 ETO12200.1 - 9.3e-36 118.8 11.8 9.9e-05 21.8 0.0 9.8 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_8 PF13181.1 ETO12200.1 - 2.1e-31 105.3 57.7 2.4e-05 23.8 0.1 10.1 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_17 PF13431.1 ETO12200.1 - 1.6e-19 68.3 17.8 0.0075 16.3 0.1 9.9 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 ETO12200.1 - 1.7e-19 69.9 0.0 1.5e-05 25.5 0.0 6.2 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.1 ETO12200.1 - 2.5e-16 58.9 11.3 0.077 13.4 0.0 9.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO12200.1 - 1.2e-13 50.3 0.0 3.1 8.6 0.0 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO12200.1 - 1e-10 41.5 28.9 0.00083 19.4 3.3 6.8 3 2 3 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 DUF2225 PF09986.4 ETO12200.1 - 6.2e-07 29.0 22.1 0.00096 18.6 0.7 4.7 1 1 5 6 6 6 3 Uncharacterized protein conserved in bacteria (DUF2225) SHNi-TPR PF10516.4 ETO12200.1 - 1.9e-06 27.0 1.3 0.07 12.3 0.0 5.5 6 0 0 6 6 6 2 SHNi-TPR TPR_19 PF14559.1 ETO12200.1 - 7.6e-06 26.1 2.1 0.28 11.5 0.0 5.1 3 2 3 6 6 6 1 Tetratricopeptide repeat TPR_3 PF07720.7 ETO12200.1 - 8.4e-05 22.2 23.5 0.44 10.4 0.1 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat DUF627 PF04781.7 ETO12200.1 - 0.00053 19.5 12.9 1.4 8.5 0.1 5.7 4 2 2 6 6 5 2 Protein of unknown function (DUF627) MIT PF04212.13 ETO12200.1 - 0.001 18.9 24.8 0.34 10.8 0.1 7.5 9 0 0 9 9 8 1 MIT (microtubule interacting and transport) domain RPN7 PF10602.4 ETO12200.1 - 0.012 14.9 20.4 0.21 10.9 0.4 5.7 3 2 3 6 6 6 0 26S proteasome subunit RPN7 PPR PF01535.15 ETO12200.1 - 0.2 11.7 10.6 4.3 7.5 0.0 5.5 7 0 0 7 7 4 0 PPR repeat Prefoldin PF02996.12 ETO12200.1 - 1.3 8.6 13.2 15 5.2 0.0 5.9 5 2 2 7 7 7 0 Prefoldin subunit CesA PF11439.3 ETO12200.1 - 1.4 8.8 5.3 0.92 9.4 0.1 3.3 4 0 0 4 4 4 0 Type III secretion system filament chaperone CesA Peptidase_C14 PF00656.17 ETO12201.1 - 1.8e-11 44.2 0.7 9.6e-11 41.8 0.1 2.3 2 1 0 2 2 2 1 Caspase domain DUF4364 PF14277.1 ETO12201.1 - 0.027 14.0 0.2 0.088 12.4 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) DWNN PF08783.6 ETO12201.1 - 0.2 11.6 2.5 3.9 7.4 0.1 2.7 2 0 0 2 2 2 0 DWNN domain ATP_transf PF09830.4 ETO12202.1 - 3.8e-07 29.8 0.0 6.9e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.18 ETO12202.1 - 0.0014 19.1 0.1 0.0046 17.4 0.0 1.9 1 1 1 2 2 2 1 HIT domain zf-C2H2 PF00096.21 ETO12203.1 - 0.033 14.5 0.2 0.072 13.4 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type DHHW PF14286.1 ETO12203.1 - 0.048 12.9 2.5 0.052 12.8 1.7 1.0 1 0 0 1 1 1 0 DHHW protein zf-H2C2_2 PF13465.1 ETO12203.1 - 0.44 10.9 3.7 2 8.8 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double domain MAGE PF01454.14 ETO12203.1 - 1.3 8.3 7.5 2.2 7.5 5.2 1.4 1 1 0 1 1 1 0 MAGE family Myosin_tail_1 PF01576.14 ETO12204.1 - 0.0037 15.0 6.2 0.004 14.9 4.3 1.0 1 0 0 1 1 1 1 Myosin tail Syntaxin PF00804.20 ETO12204.1 - 0.012 15.7 3.8 0.014 15.5 2.6 1.1 1 0 0 1 1 1 0 Syntaxin DUF3552 PF12072.3 ETO12204.1 - 0.02 14.1 5.4 0.021 14.0 3.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Osmo_CC PF08946.5 ETO12204.1 - 0.038 14.0 2.7 0.038 14.0 1.8 2.0 1 1 1 2 2 2 0 Osmosensory transporter coiled coil Mga PF05043.8 ETO12204.1 - 0.083 13.1 0.5 0.095 12.9 0.4 1.1 1 0 0 1 1 1 0 Mga helix-turn-helix domain Mer2 PF09074.5 ETO12204.1 - 0.087 12.7 4.8 0.094 12.6 3.3 1.0 1 0 0 1 1 1 0 Mer2 Viral_P18 PF04521.8 ETO12204.1 - 0.098 12.0 1.0 0.12 11.8 0.7 1.1 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein YkuI_C PF10388.4 ETO12204.1 - 0.11 12.1 3.3 0.11 12.1 2.3 1.0 1 0 0 1 1 1 0 EAL-domain associated signalling protein domain DUF148 PF02520.12 ETO12204.1 - 0.18 11.6 5.4 0.42 10.4 3.8 1.5 1 1 0 1 1 1 0 Domain of unknown function DUF148 P4Ha_N PF08336.6 ETO12204.1 - 0.21 11.3 2.9 0.44 10.3 2.0 1.6 1 1 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Mvb12 PF09452.5 ETO12204.1 - 0.22 11.7 1.4 0.28 11.3 0.9 1.3 1 1 0 1 1 1 0 ESCRT-I subunit Mvb12 DUF2228 PF10228.4 ETO12204.1 - 0.25 10.8 2.3 0.29 10.6 1.6 1.0 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) ParB PF08775.5 ETO12204.1 - 0.28 11.4 3.8 0.6 10.4 2.6 1.6 1 1 0 1 1 1 0 ParB family KH_5 PF13184.1 ETO12204.1 - 0.3 10.9 2.3 0.54 10.0 1.6 1.4 1 1 0 1 1 1 0 NusA-like KH domain Fzo_mitofusin PF04799.8 ETO12204.1 - 0.34 10.2 2.8 0.38 10.1 1.6 1.4 1 1 1 2 2 2 0 fzo-like conserved region SlyX PF04102.7 ETO12204.1 - 0.42 11.0 5.3 0.98 9.8 1.6 1.9 1 1 1 2 2 2 0 SlyX AbiH PF14253.1 ETO12204.1 - 0.55 9.7 4.3 0.56 9.7 3.0 1.0 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH IncA PF04156.9 ETO12204.1 - 0.75 9.3 3.6 0.79 9.2 2.5 1.1 1 0 0 1 1 1 0 IncA protein AF0941-like PF14591.1 ETO12205.1 - 0.044 13.8 1.0 0.044 13.8 0.7 1.8 2 0 0 2 2 2 0 AF0941-like 2OG-FeII_Oxy_3 PF13640.1 ETO12206.1 - 0.0073 16.8 0.0 0.051 14.0 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF2621 PF11084.3 ETO12206.1 - 0.02 14.6 0.0 3.3 7.3 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2621) Hist_rich_Ca-bd PF10529.4 ETO12206.1 - 0.075 13.0 2.6 0.19 11.7 1.8 1.7 1 0 0 1 1 1 0 Histidine-rich Calcium-binding repeat region CENP-W PF15510.1 ETO12208.1 - 0.012 15.5 1.0 0.012 15.5 0.7 2.2 2 1 0 2 2 2 0 Centromere kinetochore component W GCK PF07802.6 ETO12209.1 - 0.05 13.7 0.1 0.075 13.1 0.1 1.3 1 0 0 1 1 1 0 GCK domain WD40 PF00400.27 ETO12211.1 - 1.3e-31 107.3 11.3 1.1e-10 41.0 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO12211.1 - 7.9e-09 34.1 0.1 2.7e-05 22.4 0.1 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 WD40 PF00400.27 ETO12212.1 - 3.7e-81 264.3 13.9 1.8e-12 46.5 0.0 7.6 6 1 1 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO12212.1 - 5.7e-11 42.4 0.2 0.00077 19.2 0.0 3.2 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO12212.1 - 2.6e-08 32.5 2.7 9.5e-05 20.8 0.0 3.8 1 1 2 4 4 4 2 Cytochrome D1 heme domain Nup160 PF11715.3 ETO12212.1 - 6.2e-08 31.2 3.8 0.17 10.0 0.0 4.5 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO12212.1 - 1.3e-07 30.7 4.0 1.8 7.2 0.1 5.0 2 1 2 4 4 4 4 Nup133 N terminal like PD40 PF07676.7 ETO12212.1 - 5.2e-06 25.9 6.2 0.99 9.1 0.0 6.0 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 ETO12212.1 - 0.0016 17.7 6.9 1.9 7.9 0.0 5.3 5 0 0 5 5 5 1 Proteasome subunit A N-terminal signature Resistin PF06954.6 ETO12212.1 - 0.0023 18.1 0.3 12 6.2 0.1 4.1 3 2 1 4 4 4 1 Resistin Coatomer_WDAD PF04053.9 ETO12212.1 - 0.004 16.0 0.0 0.65 8.7 0.0 2.2 1 1 1 2 2 2 2 Coatomer WD associated region DPPIV_N PF00930.16 ETO12212.1 - 0.0085 14.7 0.3 9.5 4.6 0.0 3.7 1 1 3 4 4 4 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Ricin_B_lectin PF00652.17 ETO12212.1 - 0.015 15.3 2.5 3.1 7.8 0.3 3.2 2 1 1 3 3 3 0 Ricin-type beta-trefoil lectin domain Mid2 PF04478.7 ETO12212.1 - 0.13 11.7 2.1 40 3.5 0.0 3.6 3 1 1 4 4 4 0 Mid2 like cell wall stress sensor P53_C PF11619.3 ETO12213.1 - 0.087 12.5 0.2 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Transcription factor P53 - C terminal domain zf-MIZ PF02891.15 ETO12213.1 - 0.19 11.2 3.3 0.15 11.6 1.1 1.6 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger ZZ PF00569.12 ETO12213.1 - 0.69 9.4 3.1 0.2 11.2 0.4 1.4 2 0 0 2 2 2 0 Zinc finger, ZZ type Glucokinase PF02685.11 ETO12214.1 - 0.11 11.2 0.1 0.15 10.8 0.1 1.1 1 0 0 1 1 1 0 Glucokinase MogR_DNAbind PF12181.3 ETO12214.1 - 0.15 11.8 1.5 0.2 11.4 1.0 1.1 1 0 0 1 1 1 0 DNA binding domain of the motility gene repressor (MogR) Inositol_P PF00459.20 ETO12216.1 - 2.7e-41 141.6 0.0 4.9e-32 111.2 0.0 2.1 2 0 0 2 2 2 2 Inositol monophosphatase family TMEMspv1-c74-12 PF11044.3 ETO12218.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein TPMT PF05724.6 ETO12220.1 - 6.1e-10 38.9 0.0 7.4e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) ECH_C PF13766.1 ETO12221.1 - 8.2e-33 113.0 0.4 1.4e-32 112.2 0.3 1.4 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 ETO12221.1 - 5.9e-26 91.0 0.0 5.4e-25 87.9 0.0 2.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family IL12 PF03039.9 ETO12221.1 - 0.0037 16.3 0.1 0.006 15.7 0.1 1.2 1 0 0 1 1 1 1 Interleukin-12 alpha subunit ETRAMP PF09716.5 ETO12221.1 - 0.037 13.9 0.1 0.098 12.6 0.1 1.8 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) HTH_9 PF08221.6 ETO12221.1 - 0.07 13.0 0.1 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Tn7_Tnp_TnsA_C PF08721.6 ETO12221.1 - 0.098 12.6 0.1 0.41 10.7 0.0 2.1 2 0 0 2 2 2 0 TnsA endonuclease C terminal WD40 PF00400.27 ETO12222.1 - 9.9e-78 253.4 17.8 6.5e-12 44.8 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO12222.1 - 3.5e-08 32.1 1.1 0.0026 16.1 0.0 3.1 1 1 1 3 3 3 3 Cytochrome D1 heme domain Nup160 PF11715.3 ETO12222.1 - 5.5e-05 21.5 7.1 0.096 10.8 0.1 5.0 1 1 4 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO12222.1 - 0.0015 17.3 16.7 0.52 8.9 1.8 5.4 1 1 4 5 5 5 3 Nup133 N terminal like PLD_C PF12357.3 ETO12222.1 - 0.018 14.5 0.1 1.2e+02 2.3 0.0 5.1 6 1 1 7 7 7 0 Phospholipase D C terminal PQQ PF01011.16 ETO12222.1 - 0.054 13.0 0.2 3.6 7.2 0.0 3.3 4 0 0 4 4 4 0 PQQ enzyme repeat PD40 PF07676.7 ETO12222.1 - 6.6 6.5 13.6 79 3.0 0.1 6.0 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 ETO12223.1 - 1.3e-33 113.6 16.0 5.9e-11 41.8 0.1 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO12223.1 - 2.5e-06 25.9 1.8 0.0019 16.3 0.2 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 NAAA-beta PF15508.1 ETO12224.1 - 0.41 11.0 3.1 8 6.8 0.4 2.2 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Kelch_2 PF07646.10 ETO12226.1 - 0.076 12.8 0.9 1.8 8.4 0.0 3.1 3 0 0 3 3 3 0 Kelch motif Kelch_1 PF01344.20 ETO12226.1 - 0.23 11.0 5.0 11 5.6 0.1 3.6 4 0 0 4 4 4 0 Kelch motif CENP-P PF13096.1 ETO12228.1 - 0.095 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P LCM PF04072.9 ETO12229.1 - 1e-38 132.7 0.0 1.9e-38 131.8 0.0 1.5 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase DUF4312 PF14189.1 ETO12229.1 - 0.03 14.1 3.8 4.4 7.2 0.2 3.8 2 1 2 4 4 4 0 Domain of unknown function (DUF4312) ART PF01129.13 ETO12230.1 - 0.00013 21.2 0.1 0.00024 20.2 0.1 1.4 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase G-alpha PF00503.15 ETO12231.1 - 0.051 12.2 3.5 0.049 12.3 1.5 1.4 1 1 1 2 2 2 0 G-protein alpha subunit AAA_18 PF13238.1 ETO12231.1 - 0.16 12.3 1.8 3.8 7.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain Kelch_6 PF13964.1 ETO12233.1 - 1.1e-08 34.8 1.8 0.0022 18.1 0.0 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO12233.1 - 6.8e-07 28.8 1.7 0.0044 16.7 0.1 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO12233.1 - 3e-06 27.0 1.5 0.0059 16.5 0.1 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETO12233.1 - 1.3e-05 24.8 0.0 0.26 11.1 0.0 3.0 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO12233.1 - 6e-05 22.5 2.0 0.41 10.2 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 ETO12233.1 - 0.033 14.3 0.2 3.4 7.9 0.0 3.8 5 0 0 5 5 5 0 Galactose oxidase, central domain WD40 PF00400.27 ETO12234.1 - 8.8e-37 123.6 1.2 1.8e-11 43.4 0.0 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO12234.1 - 0.00016 19.9 0.1 0.01 13.9 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO12234.1 - 0.00017 20.4 2.3 0.015 14.0 0.3 2.1 1 1 1 2 2 2 2 Nup133 N terminal like WD40 PF00400.27 ETO12235.1 - 2.7e-13 49.2 0.5 7.6e-12 44.6 0.0 2.4 2 1 0 2 2 2 2 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO12236.1 - 0.0045 17.1 1.5 0.56 10.4 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.20 ETO12236.1 - 0.025 14.1 1.0 1.2 8.7 0.1 2.8 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.1 ETO12236.1 - 0.035 14.0 0.5 8 6.5 0.0 3.3 3 0 0 3 3 3 0 Kelch motif WD40 PF00400.27 ETO12237.1 - 1.7e-60 198.8 19.2 1.3e-11 43.9 0.5 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO12237.1 - 3.9e-10 38.4 5.6 0.0021 16.2 0.1 4.9 2 2 2 4 4 4 4 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO12237.1 - 0.065 13.4 15.1 12 6.2 1.0 6.0 4 1 1 5 5 5 0 Kelch motif HAD PF12710.2 ETO12237.1 - 0.79 9.8 4.1 33 4.5 0.0 2.6 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase WD40 PF00400.27 ETO12238.1 - 1.3e-55 183.3 19.6 4.3e-10 39.0 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO12238.1 - 4.2e-10 38.3 6.5 0.00053 18.2 0.6 4.8 1 1 2 4 4 4 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO12238.1 - 4.1e-06 26.5 3.3 0.033 13.9 0.2 3.6 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region HAD PF12710.2 ETO12238.1 - 0.052 13.7 2.1 33 4.5 0.0 3.5 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF1778 PF08681.6 ETO12239.1 - 0.013 15.3 0.2 0.027 14.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1778) Holin_LLH PF09682.5 ETO12240.1 - 0.044 13.9 0.6 0.074 13.1 0.4 1.3 1 0 0 1 1 1 0 Phage holin protein (Holin_LLH) Tom7 PF08038.7 ETO12241.1 - 7.2e-05 22.1 0.1 0.00014 21.2 0.1 1.4 1 0 0 1 1 1 1 TOM7 family DUF244 PF03112.9 ETO12241.1 - 0.018 14.6 0.3 0.025 14.1 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF fn3 PF00041.16 ETO12242.1 - 0.064 13.3 0.0 0.46 10.6 0.0 2.5 2 0 0 2 2 2 0 Fibronectin type III domain Nop14 PF04147.7 ETO12242.1 - 8 4.2 43.8 11 3.8 30.3 1.1 1 0 0 1 1 1 0 Nop14-like family Proteasome PF00227.21 ETO12243.1 - 4.4e-48 163.0 0.8 5.6e-48 162.7 0.5 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 ETO12243.1 - 0.032 13.4 0.0 0.032 13.4 0.0 2.1 3 0 0 3 3 3 0 Proteasome beta subunits C terminal RabGGT_insert PF07711.6 ETO12244.1 - 0.098 12.4 0.0 0.28 11.0 0.0 1.8 1 1 0 1 1 1 0 Rab geranylgeranyl transferase alpha-subunit, insert domain MerB PF03243.10 ETO12245.1 - 2.1e-05 24.3 0.1 2.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Alkylmercury lyase DUF2604 PF10790.4 ETO12246.1 - 0.0033 17.5 0.1 0.0067 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of Unknown function (DUF2604) Serinc PF03348.10 ETO12247.1 - 1.5e-05 23.8 5.8 0.005 15.5 0.1 2.1 2 0 0 2 2 2 2 Serine incorporator (Serinc) DUF3753 PF12575.3 ETO12247.1 - 0.41 10.4 4.5 0.29 10.9 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) Mt_ATP-synt_D PF05873.7 ETO12248.1 - 0.098 12.2 0.3 0.23 11.0 0.0 1.8 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) COX_ARM PF06481.9 ETO12249.1 - 0.02 14.5 0.4 0.055 13.1 0.1 2.0 2 1 1 3 3 3 0 COX Aromatic Rich Motif TrkA_C PF02080.16 ETO12251.1 - 3.5e-10 39.3 0.0 9.8e-10 37.8 0.0 1.7 2 0 0 2 2 2 1 TrkA-C domain TMEM156 PF15106.1 ETO12254.1 - 0.023 13.9 0.6 0.025 13.8 0.4 1.0 1 0 0 1 1 1 0 TMEM156 protein family CCDC144C PF14915.1 ETO12254.1 - 0.18 10.7 7.5 0.19 10.5 5.2 1.0 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region WD40 PF00400.27 ETO12255.1 - 2.6e-63 207.7 29.8 1.1e-11 44.1 0.4 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO12255.1 - 8.6e-13 47.2 9.5 0.00058 18.1 0.3 5.1 1 1 4 5 5 5 5 Nucleoporin Nup120/160 Herpes_U47 PF05467.6 ETO12255.1 - 0.014 13.2 0.3 1.5 6.5 0.0 2.0 1 1 1 2 2 2 0 Herpesvirus glycoprotein U47 DUF843 PF05814.6 ETO12256.1 - 0.0068 16.1 0.5 0.0068 16.1 0.3 2.4 2 0 0 2 2 2 1 Baculovirus protein of unknown function (DUF843) Protocadherin PF08374.6 ETO12256.1 - 0.0085 15.7 0.5 0.0085 15.7 0.4 1.7 1 1 0 1 1 1 1 Protocadherin TMEM154 PF15102.1 ETO12256.1 - 0.01 15.5 1.6 0.01 15.5 1.1 2.6 3 0 0 3 3 3 0 TMEM154 protein family Peptidase_S49_N PF08496.5 ETO12256.1 - 0.014 15.2 0.2 0.014 15.2 0.2 2.3 2 1 0 2 2 2 0 Peptidase family S49 N-terminal ATP-synt_8 PF00895.15 ETO12256.1 - 0.014 15.6 1.4 0.21 11.8 0.1 2.7 2 0 0 2 2 2 0 ATP synthase protein 8 Tmemb_9 PF05434.6 ETO12256.1 - 0.015 15.0 0.8 0.015 15.0 0.5 1.7 2 0 0 2 2 2 0 TMEM9 Tetraspannin PF00335.15 ETO12256.1 - 0.073 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Tetraspanin family DUF1510 PF07423.6 ETO12256.1 - 0.076 12.3 0.1 0.076 12.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Shisa PF13908.1 ETO12256.1 - 0.1 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Baculo_11_kDa PF06143.6 ETO12256.1 - 0.15 11.4 5.2 0.38 10.1 3.6 1.7 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF2201_N PF13203.1 ETO12256.1 - 0.35 9.9 3.4 0.31 10.1 0.1 1.9 2 0 0 2 2 2 0 Putative metallopeptidase domain DUF2615 PF11027.3 ETO12256.1 - 2.3 8.1 5.9 0.36 10.7 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2615) Kinesin PF00225.18 ETO12257.1 - 8.4e-05 21.4 1.1 0.00011 21.0 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain TMF_DNA_bd PF12329.3 ETO12257.1 - 0.018 14.8 0.3 0.018 14.8 0.2 3.8 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.3 ETO12257.1 - 0.061 13.2 14.6 1.7 8.5 6.4 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding NYD-SP28 PF14772.1 ETO12257.1 - 0.072 13.1 16.4 3 7.9 0.2 3.9 3 1 0 3 3 3 0 Sperm tail Fib_alpha PF08702.5 ETO12257.1 - 0.15 12.1 12.0 3.1 7.9 0.1 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Sec2p PF06428.6 ETO12257.1 - 0.33 10.8 0.1 0.33 10.8 0.1 3.4 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p Exo_endo_phos_2 PF14529.1 ETO12258.1 - 0.0018 17.8 0.1 0.0047 16.5 0.1 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Syntaxin PF00804.20 ETO12258.1 - 0.15 12.1 3.2 0.088 12.9 0.6 1.8 2 0 0 2 2 2 0 Syntaxin WD40 PF00400.27 ETO12259.1 - 4.5e-78 254.5 14.0 5.8e-13 48.1 0.8 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO12259.1 - 5.8e-11 42.4 3.5 0.00018 21.3 0.0 3.7 1 1 4 5 5 5 5 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO12259.1 - 3e-08 32.2 7.9 0.043 11.9 0.0 5.3 1 1 4 5 5 5 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 ETO12259.1 - 4.9e-06 25.5 1.2 0.0072 15.1 0.1 3.0 1 1 2 3 3 3 2 Coatomer WD associated region DUF1258 PF06869.7 ETO12259.1 - 8.2e-06 25.0 1.8 0.14 11.1 0.1 3.2 2 1 1 3 3 3 2 Protein of unknown function (DUF1258) PD40 PF07676.7 ETO12259.1 - 1.5e-05 24.5 10.6 1.3 8.7 0.0 5.7 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO12259.1 - 5e-05 21.7 0.3 1.1 7.5 0.0 3.2 2 1 2 4 4 4 3 Cytochrome D1 heme domain Resistin PF06954.6 ETO12259.1 - 6.7e-05 23.0 0.8 7.1 6.9 0.0 4.2 2 2 2 4 4 4 1 Resistin PQQ_2 PF13360.1 ETO12259.1 - 6.8e-05 22.4 1.2 0.00053 19.5 0.8 2.2 1 1 0 1 1 1 1 PQQ-like domain Str_synth PF03088.11 ETO12259.1 - 0.00051 20.0 0.0 6.5 6.8 0.0 4.2 3 1 2 5 5 5 1 Strictosidine synthase PA14 PF07691.7 ETO12259.1 - 0.00064 19.3 0.4 0.18 11.4 0.0 2.7 2 1 0 2 2 2 1 PA14 domain Proteasome_A_N PF10584.4 ETO12259.1 - 0.012 14.9 4.5 15 5.0 0.0 5.0 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature CPSF_A PF03178.10 ETO12259.1 - 0.037 13.1 0.1 0.41 9.6 0.0 2.5 1 1 1 2 2 2 0 CPSF A subunit region Pam16 PF03656.8 ETO12259.1 - 0.07 12.9 0.0 0.31 10.8 0.0 2.0 3 0 0 3 3 3 0 Pam16 TFIIH_BTF_p62_N PF08567.6 ETO12259.1 - 0.083 12.5 0.1 32 4.2 0.0 3.3 2 1 1 3 3 3 0 TFIIH p62 subunit, N-terminal domain DNA_pol3_gamma3 PF12169.3 ETO12259.1 - 0.15 11.8 0.0 1.4 8.6 0.0 2.4 2 1 1 3 3 3 0 DNA polymerase III subunits gamma and tau domain III Colicin_Ia PF11504.3 ETO12259.1 - 0.53 10.2 3.3 66 3.5 0.0 4.3 5 0 0 5 5 5 0 Colicin Ia CAP_GLY PF01302.20 ETO12260.1 - 3.2e-25 87.6 9.4 1.3e-16 59.9 0.6 2.6 2 1 0 2 2 2 2 CAP-Gly domain Arc_trans_TRASH PF08394.5 ETO12260.1 - 0.081 13.0 0.2 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 Archaeal TRASH domain ERAP1_C PF11838.3 ETO12261.1 - 1.1e-09 37.9 0.0 1.5e-09 37.5 0.0 1.0 1 0 0 1 1 1 1 ERAP1-like C-terminal domain WD40 PF00400.27 ETO12262.1 - 2e-41 138.4 15.0 7.2e-13 47.8 0.0 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO12262.1 - 5.7e-12 44.5 1.7 0.0031 15.7 0.0 4.0 1 1 3 4 4 4 4 Nucleoporin Nup120/160 DUF1900 PF08954.6 ETO12262.1 - 0.0037 16.8 0.0 3 7.3 0.0 3.0 3 1 1 4 4 4 2 Domain of unknown function (DUF1900) Cupin_8 PF13621.1 ETO12262.1 - 0.049 13.1 0.4 0.06 12.8 0.3 1.1 1 0 0 1 1 1 0 Cupin-like domain DUF3601 PF12208.3 ETO12262.1 - 0.11 12.4 0.0 0.39 10.6 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3601) Kelch_6 PF13964.1 ETO12262.1 - 0.2 11.8 5.5 17 5.7 0.1 4.0 4 1 0 4 4 4 0 Kelch motif WD40 PF00400.27 ETO12263.1 - 1e-16 60.0 0.7 4e-08 32.8 0.5 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO12263.1 - 0.0007 17.8 0.1 0.001 17.3 0.0 1.4 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Pox_H7 PF04787.7 ETO12263.1 - 0.81 9.4 3.3 0.88 9.3 0.8 1.8 2 0 0 2 2 2 0 Late protein H7 WD40 PF00400.27 ETO12264.1 - 1.1e-14 53.6 6.1 5.6e-11 41.8 0.8 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO12264.1 - 9e-06 24.0 0.3 9.9e-06 23.9 0.2 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 WD40 PF00400.27 ETO12265.1 - 3.7e-05 23.4 0.2 6.9e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 WD domain, G-beta repeat N-glycanase_N PF09112.5 ETO12265.1 - 0.013 14.8 1.4 0.051 12.9 0.4 2.1 1 1 0 2 2 2 0 Peptide-N-glycosidase F, N terminal SOBP PF15279.1 ETO12266.1 - 0.006 17.0 23.4 0.006 17.0 16.2 2.6 2 1 0 2 2 2 1 Sine oculis-binding protein ACT_4 PF13291.1 ETO12266.1 - 5.6 7.3 7.5 86 3.5 0.0 2.4 2 0 0 2 2 2 0 ACT domain adh_short PF00106.20 ETO12268.1 - 6.9e-20 71.6 0.0 2.5e-16 60.0 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 ETO12268.1 - 2.8e-09 37.1 0.0 6.5e-08 32.6 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETO12268.1 - 7.8e-05 22.2 0.0 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 ETO12268.1 - 8.6e-05 22.2 0.0 0.00019 21.1 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ETO12268.1 - 0.0031 17.5 0.2 0.0098 15.9 0.2 1.8 1 1 0 1 1 1 1 NADH(P)-binding TPR_12 PF13424.1 ETO12269.1 - 2.3e-53 178.0 20.9 3.5e-17 62.1 0.2 4.2 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETO12269.1 - 1.3e-13 50.3 18.1 5.5e-06 25.9 3.4 3.7 2 1 2 4 4 4 4 TPR repeat TPR_7 PF13176.1 ETO12269.1 - 2.6e-13 48.6 7.3 0.0059 16.3 0.0 6.6 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO12269.1 - 4.9e-12 45.3 0.0 0.16 11.9 0.0 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO12269.1 - 3.2e-11 42.2 21.2 0.00038 20.1 0.2 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO12269.1 - 3.2e-10 39.1 30.0 0.00059 19.3 0.8 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO12269.1 - 1.6e-09 36.8 23.6 0.017 14.8 1.1 5.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETO12269.1 - 2.6e-05 24.0 9.4 0.74 10.1 0.2 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO12269.1 - 2.7e-05 24.3 0.0 3.2 8.6 0.0 4.3 4 1 0 4 4 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO12269.1 - 0.0022 17.1 0.2 2.6 7.3 0.0 2.8 2 0 0 2 2 2 2 SHNi-TPR MIT PF04212.13 ETO12269.1 - 0.081 12.8 4.1 2.8 7.8 0.0 4.2 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 ETO12269.1 - 0.16 12.5 2.7 37 5.0 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Auxin_repressed PF05564.7 ETO12270.1 - 0.19 12.3 7.5 1.9 9.1 3.8 2.2 1 1 1 2 2 2 0 Dormancy/auxin associated protein Apc5 PF12862.2 ETO12271.1 - 4.2e-19 68.1 5.1 6.9e-19 67.4 2.7 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_20 PF14561.1 ETO12271.1 - 0.00083 19.4 1.4 1.3 9.2 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat Vpu PF00558.14 ETO12271.1 - 0.0048 16.4 0.4 0.027 14.0 0.0 2.2 1 1 1 2 2 2 1 Vpu protein DUF2627 PF11118.3 ETO12271.1 - 0.035 14.1 0.1 0.093 12.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) Chorismate_bind PF00425.13 ETO12271.1 - 0.09 12.0 0.7 0.17 11.1 0.5 1.4 1 0 0 1 1 1 0 chorismate binding enzyme Peptidase_S49_N PF08496.5 ETO12271.1 - 0.97 9.2 9.4 0.32 10.7 4.0 2.0 1 1 0 1 1 1 0 Peptidase family S49 N-terminal BTB PF00651.26 ETO12272.1 - 3.5e-21 75.2 4.5 6.7e-20 71.1 0.3 2.6 2 1 1 3 3 3 2 BTB/POZ domain BACK PF07707.10 ETO12272.1 - 1.5e-06 27.9 1.4 2.6e-05 24.0 0.1 3.0 3 1 1 4 4 4 1 BTB And C-terminal Kelch Cyclin_C PF02984.14 ETO12272.1 - 0.044 13.7 0.8 0.26 11.2 0.1 2.1 2 0 0 2 2 2 0 Cyclin, C-terminal domain Ank_4 PF13637.1 ETO12273.1 - 0.003 18.0 0.8 0.034 14.6 0.3 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 ETO12273.1 - 0.012 15.4 0.1 0.042 13.6 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.2 ETO12273.1 - 0.012 15.9 0.0 0.029 14.7 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO12273.1 - 0.033 14.4 0.1 1.5 9.3 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat Tho2 PF11262.3 ETO12273.1 - 0.043 12.8 0.8 0.08 11.9 0.0 1.8 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 UPRTase PF14681.1 ETO12274.1 - 2.4e-20 72.6 0.1 2.1e-17 63.0 0.0 3.0 2 1 0 2 2 2 2 Uracil phosphoribosyltransferase KCl_Cotrans_1 PF03522.10 ETO12274.1 - 0.06 12.8 3.3 1.4 8.5 0.2 2.7 2 0 0 2 2 2 0 K-Cl Co-transporter type 1 (KCC1) DUF726 PF05277.7 ETO12275.1 - 1.2e-43 149.3 0.3 8.9e-26 90.5 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF726) DUF4642 PF15484.1 ETO12275.1 - 0.023 14.6 3.9 0.035 14.0 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) Abhydrolase_5 PF12695.2 ETO12275.1 - 0.039 13.7 0.0 0.055 13.2 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF417 PF04224.7 ETO12275.1 - 0.082 12.2 0.2 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF417 Zip PF02535.17 ETO12275.1 - 0.13 11.2 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter UPF0565 PF10561.4 ETO12275.1 - 0.32 9.8 6.3 0.45 9.3 0.0 2.1 1 1 0 2 2 2 0 Uncharacterised protein family UPF0565 DUF726 PF05277.7 ETO12276.1 - 7e-19 67.9 2.2 2e-14 53.2 1.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF726) CENP-B_dimeris PF09026.5 ETO12276.1 - 0.02 15.1 2.6 0.02 15.1 1.8 3.4 4 0 0 4 4 4 0 Centromere protein B dimerisation domain Cytochrom_B558a PF05038.8 ETO12276.1 - 0.028 14.0 0.1 0.079 12.5 0.1 1.7 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit DnaJ PF00226.26 ETO12277.1 - 1.4e-30 104.7 1.4 3.7e-30 103.4 0.9 1.8 1 0 0 1 1 1 1 DnaJ domain Takusan PF04822.8 ETO12278.1 - 0.33 10.7 7.8 0.85 9.4 5.4 1.6 1 0 0 1 1 1 0 Takusan FH2 PF02181.18 ETO12279.1 - 1.6e-48 165.4 8.6 3.1e-35 121.7 2.0 3.4 4 0 0 4 4 4 3 Formin Homology 2 Domain DUF572 PF04502.8 ETO12279.1 - 3 6.9 29.9 5.7 6.0 20.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Neur_chan_memb PF02932.11 ETO12280.1 - 2 8.2 8.0 38 4.0 5.5 2.3 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AA_kinase PF00696.23 ETO12281.1 - 2.1e-09 37.3 0.1 1.6e-08 34.4 0.0 2.2 1 1 1 3 3 3 1 Amino acid kinase family Neur_chan_LBD PF02931.18 ETO12282.1 - 0.0019 17.3 0.1 0.0025 17.0 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Rhodanese PF00581.15 ETO12283.1 - 0.00019 21.7 0.0 0.00043 20.5 0.0 1.6 1 1 0 1 1 1 1 Rhodanese-like domain PGM_PMM_I PF02878.11 ETO12283.1 - 0.0046 16.4 0.0 0.0072 15.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I UDPGP PF01704.13 ETO12284.1 - 3.8e-42 144.2 0.0 6.4e-42 143.5 0.0 1.3 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase MMR_HSR1 PF01926.18 ETO12284.1 - 2.6e-19 69.2 0.2 8.1e-19 67.6 0.2 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETO12284.1 - 1.7e-06 27.4 0.0 3.2e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.11 ETO12284.1 - 1.1e-05 24.7 0.0 2.7e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 AIG1 family Arf PF00025.16 ETO12284.1 - 0.00027 20.2 0.5 0.78 8.9 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 ETO12284.1 - 0.0005 20.5 0.1 0.003 18.0 0.1 2.4 1 1 0 1 1 1 1 Miro-like protein NTP_transf_3 PF12804.2 ETO12284.1 - 0.027 14.5 0.0 0.085 12.9 0.0 1.9 1 0 0 1 1 1 0 MobA-like NTP transferase domain Dynamin_N PF00350.18 ETO12284.1 - 9.6 5.9 14.9 2.6 7.8 0.2 3.4 2 2 1 3 3 3 0 Dynamin family Nop14 PF04147.7 ETO12286.1 - 0.00062 17.8 9.8 0.00071 17.6 6.8 1.1 1 0 0 1 1 1 1 Nop14-like family CobT PF06213.7 ETO12286.1 - 0.00069 18.8 4.4 0.00098 18.3 3.1 1.3 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT DUF2457 PF10446.4 ETO12286.1 - 0.028 13.1 16.2 0.048 12.4 11.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Vfa1 PF08432.5 ETO12286.1 - 0.052 13.5 9.2 0.11 12.5 6.4 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 ETO12286.1 - 0.11 10.4 12.7 0.16 9.9 8.8 1.2 1 0 0 1 1 1 0 CDC45-like protein FLO_LFY PF01698.11 ETO12286.1 - 0.19 10.5 5.1 0.12 11.2 2.0 1.7 2 0 0 2 2 2 0 Floricaula / Leafy protein DUF4611 PF15387.1 ETO12286.1 - 0.68 10.1 12.9 1 9.5 8.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) RRN3 PF05327.6 ETO12286.1 - 1 7.4 12.3 1.5 6.8 8.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TRAP_alpha PF03896.11 ETO12286.1 - 1.8 7.5 9.5 3.2 6.6 6.6 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Brix PF04427.13 ETO12287.1 - 1.5e-32 112.7 8.5 5.8e-17 61.9 0.2 2.6 3 0 0 3 3 3 2 Brix domain CDC45 PF02724.9 ETO12287.1 - 0.00082 17.5 6.8 0.00082 17.5 4.7 2.1 2 0 0 2 2 2 1 CDC45-like protein Pox_Ag35 PF03286.9 ETO12287.1 - 0.002 17.6 11.2 0.002 17.6 7.7 2.4 2 0 0 2 2 2 1 Pox virus Ag35 surface protein Dicty_REP PF05086.7 ETO12287.1 - 0.35 8.5 21.9 0.043 11.5 9.2 2.1 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Mem_trans PF03547.13 ETO12288.1 - 0.00093 17.5 1.5 0.0019 16.5 1.0 1.5 1 1 0 1 1 1 1 Membrane transport protein Ndc1_Nup PF09531.5 ETO12288.1 - 0.043 12.2 2.3 0.057 11.8 1.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1777 PF08648.7 ETO12288.1 - 0.073 12.8 16.5 0.1 12.3 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Hid1 PF12722.2 ETO12288.1 - 0.078 10.6 14.1 0.092 10.4 9.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Menin PF05053.8 ETO12288.1 - 0.14 10.2 5.1 0.17 9.9 3.5 1.1 1 0 0 1 1 1 0 Menin Utp14 PF04615.8 ETO12288.1 - 0.24 9.5 27.8 0.31 9.1 19.3 1.0 1 0 0 1 1 1 0 Utp14 protein Ycf1 PF05758.7 ETO12288.1 - 0.34 8.5 11.9 0.39 8.3 8.2 1.1 1 0 0 1 1 1 0 Ycf1 CDC45 PF02724.9 ETO12288.1 - 0.42 8.5 25.2 0.63 8.0 17.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.3 ETO12288.1 - 0.71 8.4 9.3 1 7.9 6.4 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 HSP90 PF00183.13 ETO12288.1 - 1.8 6.8 20.9 2.4 6.4 14.5 1.3 1 0 0 1 1 1 0 Hsp90 protein BTV_NS2 PF04514.7 ETO12288.1 - 2 7.1 18.5 2.8 6.7 12.9 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FLO_LFY PF01698.11 ETO12288.1 - 4 6.1 15.6 6.1 5.5 10.8 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein BACK PF07707.10 ETO12289.1 - 0.0015 18.3 0.2 0.0036 17.1 0.1 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Daxx PF03344.10 ETO12289.1 - 0.0071 14.8 2.5 0.011 14.3 1.8 1.2 1 0 0 1 1 1 1 Daxx Family Nop14 PF04147.7 ETO12289.1 - 0.013 13.4 4.7 0.017 13.0 3.3 1.1 1 0 0 1 1 1 0 Nop14-like family SPRY PF00622.23 ETO12289.1 - 0.066 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 SPRY domain CDC45 PF02724.9 ETO12289.1 - 0.074 11.0 4.0 0.14 10.2 2.8 1.3 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.8 ETO12289.1 - 0.14 12.0 6.9 0.2 11.5 4.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Upf2 PF04050.9 ETO12289.1 - 2.1 8.0 10.4 3.8 7.2 7.2 1.3 1 0 0 1 1 1 0 Up-frameshift suppressor 2 SDA1 PF05285.7 ETO12289.1 - 8.7 5.5 12.1 15 4.7 8.4 1.3 1 0 0 1 1 1 0 SDA1 V-SNARE_C PF12352.3 ETO12290.1 - 5.2e-05 23.2 3.3 5.2e-05 23.2 2.3 2.5 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus DUF1761 PF08570.5 ETO12290.1 - 6.6e-05 22.9 2.4 0.038 14.0 0.8 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1761) Sec20 PF03908.8 ETO12290.1 - 0.056 13.1 0.2 0.056 13.1 0.2 3.7 4 0 0 4 4 4 0 Sec20 SNARE PF05739.14 ETO12291.1 - 0.00067 19.2 0.9 0.001 18.6 0.6 1.2 1 0 0 1 1 1 1 SNARE domain DASH_Dad4 PF08650.5 ETO12291.1 - 0.0029 17.4 0.1 0.0064 16.3 0.1 1.6 1 0 0 1 1 1 1 DASH complex subunit Dad4 XLF PF09302.6 ETO12291.1 - 0.014 15.1 0.3 0.014 15.1 0.2 1.6 2 0 0 2 2 2 0 XLF (XRCC4-like factor) LAT PF15234.1 ETO12291.1 - 0.055 12.9 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells WD40 PF00400.27 ETO12292.1 - 2.5e-47 157.1 22.2 1.7e-10 40.3 1.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO12292.1 - 0.033 12.9 0.3 7.3 5.2 0.1 2.9 1 1 1 3 3 3 0 Nup133 N terminal like UCH PF00443.24 ETO12294.1 - 5.9e-24 84.6 1.2 5.9e-24 84.6 0.8 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO12294.1 - 3.8e-07 29.8 0.0 9.9e-07 28.4 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 ETO12295.1 - 1.2e-08 34.4 1.3 2.2e-08 33.5 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DNA_pol_E_B PF04042.11 ETO12295.1 - 0.025 13.8 0.0 0.066 12.4 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B UCH_1 PF13423.1 ETO12295.1 - 0.043 13.2 0.3 0.043 13.2 0.2 2.7 2 2 1 3 3 3 0 Ubiquitin carboxyl-terminal hydrolase NodA PF02474.10 ETO12296.1 - 0.019 14.2 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein A (NodA) UN_NPL4 PF11543.3 ETO12296.1 - 0.094 13.0 0.0 0.43 10.8 0.0 2.1 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 DUF2542 PF10808.3 ETO12297.1 - 0.0057 16.8 0.0 0.016 15.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2542) G-alpha PF00503.15 ETO12298.1 - 9.4e-66 222.0 13.5 2.3e-55 187.8 3.1 2.0 2 0 0 2 2 2 2 G-protein alpha subunit Arf PF00025.16 ETO12298.1 - 0.00046 19.4 4.6 0.00064 19.0 0.7 2.7 2 2 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO12298.1 - 0.0007 19.0 2.5 1.5 8.1 0.0 3.7 2 1 2 4 4 4 2 Elongation factor Tu GTP binding domain RyR PF02026.11 ETO12298.1 - 0.0076 16.2 0.1 0.022 14.7 0.0 1.8 1 0 0 1 1 1 1 RyR domain AAA_18 PF13238.1 ETO12298.1 - 0.12 12.7 0.7 1.7 8.9 0.1 2.6 2 1 0 2 2 2 0 AAA domain WD40 PF00400.27 ETO12299.1 - 6.8e-39 130.3 2.1 1.8e-08 33.9 0.0 4.0 4 0 0 4 4 4 4 WD domain, G-beta repeat eIF2A PF08662.6 ETO12299.1 - 1.8e-06 27.8 0.1 5.7e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO12299.1 - 5.4e-06 24.8 1.6 0.14 10.2 0.1 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO12299.1 - 0.00033 19.5 4.5 0.33 9.6 0.1 3.3 1 1 2 3 3 3 2 Nup133 N terminal like WD40 PF00400.27 ETO12300.1 - 1.6e-14 53.1 15.3 0.0011 18.7 0.1 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat SGL PF08450.7 ETO12300.1 - 0.00027 20.3 0.5 0.013 14.9 0.1 3.1 3 1 0 3 3 3 1 SMP-30/Gluconolaconase/LRE-like region PQQ PF01011.16 ETO12300.1 - 0.013 14.9 0.0 1.3 8.7 0.0 3.4 3 0 0 3 3 3 0 PQQ enzyme repeat PQQ_3 PF13570.1 ETO12300.1 - 0.078 13.2 1.1 32 4.9 0.0 4.5 5 0 0 5 5 5 0 PQQ-like domain DUF3290 PF11694.3 ETO12304.1 - 0.06 13.0 5.8 0.32 10.7 1.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3290) DUF383 PF04063.9 ETO12305.1 - 0.08 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF383) Caa3_CtaG PF09678.5 ETO12305.1 - 0.25 10.2 3.7 8.2 5.2 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) WD40 PF00400.27 ETO12306.1 - 1.1e-47 158.2 20.1 5.6e-11 41.8 0.3 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO12306.1 - 1.3e-10 40.0 3.3 0.0005 18.3 0.1 4.1 3 1 1 4 4 4 4 Nucleoporin Nup120/160 HAD PF12710.2 ETO12306.1 - 0.11 12.6 0.3 1.4 9.0 0.0 2.5 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase FAM176 PF14851.1 ETO12307.1 - 0.034 13.8 0.0 0.034 13.8 0.0 2.7 2 1 1 3 3 3 0 FAM176 family WASH-7_C PF14746.1 ETO12307.1 - 0.07 12.7 0.1 0.23 11.0 0.1 1.8 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal ETRAMP PF09716.5 ETO12307.1 - 0.072 13.0 0.2 0.072 13.0 0.1 2.5 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) S1FA PF04689.8 ETO12307.1 - 0.093 12.6 0.0 0.3 10.9 0.0 1.9 1 0 0 1 1 1 0 DNA binding protein S1FA TMEM51 PF15345.1 ETO12307.1 - 3.9 7.1 16.5 1.2 8.7 0.3 2.2 1 1 1 2 2 2 0 Transmembrane protein 51 SID-1_RNA_chan PF13965.1 ETO12307.1 - 4.2 5.4 7.5 0.29 9.2 0.0 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 OAD_gamma PF04277.8 ETO12307.1 - 7.3 7.0 7.5 0.39 11.1 0.5 2.5 2 2 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DnaJ PF00226.26 ETO12308.1 - 8.4e-22 76.6 0.3 1.4e-21 75.9 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain YABBY PF04690.8 ETO12308.1 - 0.098 12.8 0.2 0.098 12.8 0.1 1.7 2 0 0 2 2 2 0 YABBY protein C2 PF00168.25 ETO12310.1 - 2.5e-50 168.2 6.3 2.3e-16 59.4 0.0 5.3 4 1 0 4 4 4 4 C2 domain WD40 PF00400.27 ETO12311.1 - 5.9e-62 203.4 10.8 2.3e-13 49.4 0.0 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO12311.1 - 3.9e-11 41.8 1.0 0.021 12.9 0.0 4.0 1 1 3 4 4 4 4 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO12311.1 - 8e-07 28.9 0.1 0.016 14.9 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 ETO12311.1 - 2e-06 26.8 3.0 0.034 12.9 0.0 3.8 1 1 3 4 4 4 3 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO12311.1 - 1.5e-05 23.4 0.2 0.1 10.9 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.7 ETO12311.1 - 9.6e-05 21.9 0.7 2 8.1 0.1 3.6 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Hira PF07569.6 ETO12311.1 - 0.00043 19.5 0.5 0.83 8.8 0.1 3.2 2 2 1 3 3 3 2 TUP1-like enhancer of split DUF3601 PF12208.3 ETO12311.1 - 0.00051 19.9 0.0 5 7.1 0.0 3.4 2 1 1 3 3 3 2 Domain of unknown function (DUF3601) Nbas_N PF15492.1 ETO12311.1 - 0.0019 17.3 0.2 0.61 9.1 0.0 3.0 1 1 2 3 3 3 1 Neuroblastoma-amplified sequence, N terminal BBS2_Mid PF14783.1 ETO12311.1 - 0.0023 17.6 0.7 11 5.8 0.0 3.8 2 2 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.1 ETO12311.1 - 0.011 15.1 0.0 0.092 12.1 0.0 2.0 1 1 1 2 2 2 0 PQQ-like domain DUF1258 PF06869.7 ETO12311.1 - 0.019 14.0 0.8 11 5.0 0.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1258) Borrelia_REV PF03978.8 ETO12312.1 - 0.034 13.8 4.9 0.11 12.2 3.5 1.8 1 1 0 1 1 1 0 Borrelia burgdorferi REV protein Chromo PF00385.19 ETO12313.1 - 9.3e-11 41.2 2.6 1.9e-10 40.2 1.8 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Nuc_sug_transp PF04142.10 ETO12314.1 - 4.4e-34 117.6 8.1 7.5e-34 116.9 5.6 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 ETO12314.1 - 1e-07 31.2 15.5 1.3e-07 30.8 10.7 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 ETO12314.1 - 0.00011 22.2 21.6 0.00027 20.9 3.1 3.1 2 2 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 ETO12314.1 - 0.0018 18.4 1.8 0.0018 18.4 1.3 2.9 3 2 0 3 3 3 1 Multidrug resistance efflux transporter DUF4131 PF13567.1 ETO12314.1 - 0.0079 15.6 1.2 0.47 9.8 0.1 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4131) Flavi_NS4A PF01350.12 ETO12314.1 - 0.21 11.1 5.1 5.7 6.4 0.0 2.5 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A TPT PF03151.11 ETO12314.1 - 1.5 8.4 22.0 1 9.0 5.1 2.4 2 1 0 2 2 2 0 Triose-phosphate Transporter family DEAD PF00270.24 ETO12315.1 - 3.7e-05 23.3 0.0 7.8e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.1 ETO12315.1 - 0.0055 16.4 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_29 PF13555.1 ETO12315.1 - 0.028 13.9 0.1 0.063 12.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.14 ETO12315.1 - 0.051 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 ETO12315.1 - 0.2 11.9 0.5 0.55 10.5 0.1 1.9 2 0 0 2 2 2 0 ABC transporter AAA_30 PF13604.1 ETO12315.1 - 0.2 11.2 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 ETO12316.1 - 0.027 14.5 0.0 0.078 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain EphA2_TM PF14575.1 ETO12317.1 - 0.018 15.4 0.2 0.018 15.4 0.1 3.1 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain OAD_gamma PF04277.8 ETO12317.1 - 0.052 13.9 2.0 1 9.8 0.0 2.4 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Conotoxin PF02950.12 ETO12317.1 - 0.13 13.0 0.3 0.13 13.0 0.2 3.4 1 1 2 3 3 3 0 Conotoxin SprA-related PF12118.3 ETO12317.1 - 0.37 10.0 33.8 0.59 9.4 23.4 1.3 1 0 0 1 1 1 0 SprA-related family DUF1510 PF07423.6 ETO12317.1 - 4.7 6.5 35.9 0.034 13.5 4.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1510) GPS PF01825.16 ETO12318.1 - 0.04 14.0 0.1 0.074 13.1 0.0 1.4 1 0 0 1 1 1 0 Latrophilin/CL-1-like GPS domain GTP_EFTU PF00009.22 ETO12320.1 - 0.00015 21.2 0.1 0.00015 21.2 0.1 3.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Daxx PF03344.10 ETO12320.1 - 1.3 7.3 33.3 1.6 7.0 23.1 1.1 1 0 0 1 1 1 0 Daxx Family SNase PF00565.12 ETO12321.1 - 1.2e-20 73.8 3.3 1.3e-09 38.2 0.1 3.6 3 0 0 3 3 3 2 Staphylococcal nuclease homologue Trypan_PARP PF05887.6 ETO12321.1 - 0.18 11.6 4.7 0.32 10.7 3.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CDC45 PF02724.9 ETO12321.1 - 2 6.3 18.2 0.27 9.2 9.6 1.7 2 0 0 2 2 2 0 CDC45-like protein TUDOR PF00567.19 ETO12322.1 - 3.2e-18 65.7 0.0 7.7e-18 64.4 0.0 1.7 1 0 0 1 1 1 1 Tudor domain SNase PF00565.12 ETO12322.1 - 9.2e-16 58.0 6.8 1.8e-10 41.0 0.0 4.2 4 1 0 4 4 4 3 Staphylococcal nuclease homologue GTP_EFTU PF00009.22 ETO12323.1 - 8.5e-35 119.8 0.0 1e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 ETO12323.1 - 4.8e-09 36.2 0.1 2.1e-08 34.2 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 ETO12323.1 - 1e-05 25.5 0.1 1.9e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 DUF342 PF03961.8 ETO12325.1 - 0.17 10.3 0.0 0.2 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) ExbD PF02472.11 ETO12326.1 - 0.032 14.2 0.3 0.055 13.4 0.2 1.4 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR DUF4379 PF14311.1 ETO12326.1 - 0.09 12.6 2.4 0.16 11.7 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4379) PBP1_TM PF14812.1 ETO12326.1 - 6.3 7.1 12.5 3.5 8.0 6.7 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myb_DNA-binding PF00249.26 ETO12328.1 - 5.2e-05 23.2 0.0 0.00016 21.6 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 ETO12328.1 - 6.2e-05 23.0 0.1 6.2e-05 23.0 0.1 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain OAD_gamma PF04277.8 ETO12328.1 - 1.2 9.5 2.3 11 6.4 0.2 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Zip PF02535.17 ETO12328.1 - 2.8 6.8 8.5 6.5 5.6 5.9 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter Lin-8 PF03353.10 ETO12329.1 - 0.071 12.3 8.0 0.1 11.8 5.5 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist GCIP PF13324.1 ETO12329.1 - 0.3 10.2 8.2 0.52 9.4 5.7 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting LMBR1 PF04791.11 ETO12329.1 - 0.49 8.9 2.1 0.61 8.5 1.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein BOFC_N PF08977.5 ETO12330.1 - 0.13 12.0 0.3 0.24 11.2 0.2 1.4 1 0 0 1 1 1 0 Bypass of Forespore C, N terminal DUF1390 PF07150.6 ETO12330.1 - 0.4 10.0 10.6 0.65 9.3 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) Secretin_N_2 PF07655.8 ETO12330.1 - 8.2 6.8 14.4 14 6.1 9.9 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain SWIRM PF04433.12 ETO12331.1 - 0.077 13.1 0.1 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 SWIRM domain Daxx PF03344.10 ETO12332.1 - 0.69 8.3 32.1 0.95 7.8 22.3 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 ETO12332.1 - 0.96 7.2 40.8 1.6 6.5 28.3 1.2 1 0 0 1 1 1 0 Nop14-like family CTP_transf_1 PF01148.15 ETO12335.1 - 4.8e-19 69.0 0.8 5.9e-19 68.7 0.6 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Glyco_tranf_2_4 PF13704.1 ETO12337.1 - 4.8 7.5 7.2 2.8 8.3 2.8 2.3 2 1 1 3 3 3 0 Glycosyl transferase family 2 Dicty_REP PF05086.7 ETO12338.1 - 0.00066 17.5 2.8 0.0009 17.1 1.9 1.2 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Chorion_2 PF03964.10 ETO12338.1 - 0.024 15.1 1.4 0.062 13.8 0.5 2.0 2 0 0 2 2 2 0 Chorion family 2 WD40 PF00400.27 ETO12339.1 - 2.3e-07 30.4 1.9 0.00018 21.2 0.5 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO12339.1 - 0.037 12.7 0.3 0.14 10.8 0.0 1.7 1 1 1 2 2 2 0 Nup133 N terminal like Kelch_2 PF07646.10 ETO12340.1 - 2.9e-08 33.1 3.2 0.00011 21.8 0.2 5.0 6 1 0 6 6 6 1 Kelch motif Kelch_6 PF13964.1 ETO12340.1 - 5.9e-07 29.3 2.6 0.012 15.7 0.2 4.4 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO12340.1 - 4.7e-06 26.0 2.9 0.0016 17.9 0.1 3.9 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO12340.1 - 0.00039 20.1 1.6 0.62 9.8 0.1 3.9 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO12340.1 - 0.00069 19.7 0.1 0.39 10.9 0.0 3.9 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO12340.1 - 0.0078 16.1 0.1 1.9 8.5 0.1 3.7 3 0 0 3 3 3 1 Kelch motif Ribonuc_red_sm PF00268.16 ETO12341.1 - 0.033 13.2 0.4 0.032 13.2 0.3 1.1 1 0 0 1 1 1 0 Ribonucleotide reductase, small chain DUF3473 PF11959.3 ETO12344.1 - 0.067 12.6 0.1 0.48 9.8 0.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3473) Helicase_C PF00271.26 ETO12345.1 - 8.3e-15 54.4 0.0 1.9e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 ETO12345.1 - 3.7e-07 29.2 0.2 2.3e-06 26.6 0.2 2.2 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Pyr_redox_2 PF07992.9 ETO12346.1 - 3.6e-17 62.8 0.0 4.7e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase eIF3g PF12353.3 ETO12349.1 - 4e-05 23.5 1.6 6.5e-05 22.8 1.1 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 ETO12349.1 - 0.003 17.1 0.1 0.1 12.2 0.1 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO12349.1 - 0.0078 16.1 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO12349.1 - 0.033 14.0 0.0 0.083 12.7 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COG6 PF06419.6 ETO12350.1 - 1.8e-08 33.0 0.2 2.1e-08 32.7 0.1 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 NPCC PF08058.6 ETO12350.1 - 0.34 10.7 2.7 0.72 9.7 0.6 2.2 1 1 1 2 2 2 0 Nuclear pore complex component zf-RING_5 PF14634.1 ETO12352.1 - 0.00018 21.1 5.5 0.0003 20.4 3.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain CobT PF06213.7 ETO12352.1 - 0.0087 15.2 3.8 0.012 14.8 2.7 1.2 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Paired_CXXCH_1 PF09699.5 ETO12352.1 - 0.022 14.2 5.9 0.054 13.0 4.1 1.6 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) zf-RING_2 PF13639.1 ETO12352.1 - 0.037 13.8 5.9 0.065 13.0 4.1 1.4 1 0 0 1 1 1 0 Ring finger domain Siva PF05458.7 ETO12352.1 - 0.082 12.4 3.2 0.073 12.6 1.2 1.7 1 1 1 2 2 2 0 Cd27 binding protein (Siva) RNA_pol_Rpc4 PF05132.9 ETO12352.1 - 0.092 12.7 3.3 0.16 11.9 2.3 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 zf-C3HC4 PF00097.20 ETO12352.1 - 0.18 11.4 7.4 0.52 10.0 5.1 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO12352.1 - 0.3 11.1 6.6 1.1 9.3 4.8 1.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CDC45 PF02724.9 ETO12352.1 - 1.4 6.9 8.1 2 6.3 5.6 1.2 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.8 ETO12352.1 - 6.2 5.2 10.0 0.82 8.1 4.2 1.5 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 TetR_C_8 PF14278.1 ETO12353.1 - 0.013 15.8 0.9 0.76 10.1 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region Ras PF00071.17 ETO12354.1 - 1e-30 106.2 0.0 1.5e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO12354.1 - 4.4e-10 40.1 0.0 8.6e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO12354.1 - 2e-05 23.8 0.0 3.1e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO12354.1 - 3.8e-05 23.2 0.0 0.00047 19.6 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 ETO12354.1 - 0.0044 16.9 0.0 0.0069 16.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DAP3 PF10236.4 ETO12354.1 - 0.084 11.7 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Ran_BP1 PF00638.13 ETO12355.1 - 1.1e-10 41.6 0.1 2.1e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain Tom22 PF04281.8 ETO12355.1 - 0.17 11.4 1.9 0.29 10.6 1.3 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Nodulin-like PF06813.8 ETO12356.1 - 0.054 12.7 0.2 0.087 12.0 0.1 1.3 1 0 0 1 1 1 0 Nodulin-like DUF4500 PF14937.1 ETO12357.1 - 0.041 13.7 0.2 3.1 7.6 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4500) MHC_I PF00129.13 ETO12357.1 - 0.064 12.5 1.6 0.1 11.9 1.1 1.3 1 0 0 1 1 1 0 Class I Histocompatibility antigen, domains alpha 1 and 2 Secretin_N_2 PF07655.8 ETO12357.1 - 0.35 11.2 12.5 1.9 8.9 8.7 2.0 2 0 0 2 2 2 0 Secretin N-terminal domain DUF2217 PF10265.4 ETO12358.1 - 0.01 14.6 0.3 0.016 13.9 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DNA_ligase_A_M PF01068.16 ETO12360.1 - 5e-58 195.8 0.1 5e-58 195.8 0.1 3.0 3 0 0 3 3 3 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 ETO12360.1 - 1.2e-30 106.5 0.1 1.2e-30 106.5 0.0 2.2 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 ETO12360.1 - 3.9e-13 49.6 0.0 1.5e-12 47.7 0.0 2.1 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region zf-CCHH PF10283.4 ETO12360.1 - 1.6e-06 27.8 1.5 3.2e-06 26.8 1.1 1.6 1 0 0 1 1 1 1 Zinc-finger (CX5CX6HX5H) motif mRNA_cap_enzyme PF01331.14 ETO12360.1 - 0.0031 17.2 0.0 0.0031 17.2 0.0 2.6 3 1 0 3 3 3 1 mRNA capping enzyme, catalytic domain Synaptonemal_3 PF15191.1 ETO12360.1 - 0.012 15.3 0.0 0.012 15.3 0.0 3.1 3 1 0 3 3 3 0 Synaptonemal complex central element protein 3 Tubulin_C PF03953.12 ETO12361.1 - 7.4e-47 158.5 0.4 7.4e-47 158.5 0.2 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin PF00091.20 ETO12361.1 - 4.6e-27 95.2 0.0 1.1e-26 94.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain NACHT PF05729.7 ETO12362.1 - 2.6e-09 36.9 0.0 5.6e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO12362.1 - 5.2e-06 26.8 0.0 5.2e-06 26.8 0.0 3.2 5 0 0 5 5 5 1 AAA domain AAA_17 PF13207.1 ETO12362.1 - 6.9e-06 26.8 0.1 6.1e-05 23.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 ETO12362.1 - 5.6e-05 23.0 2.6 8.9e-05 22.4 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETO12362.1 - 0.00041 20.4 0.0 0.0028 17.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 ETO12362.1 - 0.033 14.5 0.7 0.14 12.4 0.1 2.4 2 1 0 2 2 2 0 ABC transporter KaiC PF06745.8 ETO12362.1 - 0.046 12.8 0.3 0.67 9.0 0.0 2.7 3 0 0 3 3 3 0 KaiC AAA_33 PF13671.1 ETO12362.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 ETO12363.1 - 7.1e-159 510.7 50.5 1.3e-13 50.2 0.1 15.0 15 0 0 15 15 15 14 WD domain, G-beta repeat eIF2A PF08662.6 ETO12363.1 - 2.8e-23 82.6 0.0 0.00045 19.9 0.0 6.1 1 1 6 7 7 7 6 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO12363.1 - 3.8e-14 51.9 42.2 2.6 7.8 0.0 13.8 15 0 0 15 15 15 6 WD40-like Beta Propeller Repeat DUF3312 PF11768.3 ETO12363.1 - 6.8e-07 27.8 0.0 0.14 10.3 0.0 5.1 3 1 2 6 6 6 2 Protein of unknown function (DUF3312) CelD_N PF02927.9 ETO12363.1 - 4e-06 26.9 0.4 2.5 8.3 0.0 6.2 3 2 3 6 6 6 1 N-terminal ig-like domain of cellulase Cytochrom_D1 PF02239.11 ETO12363.1 - 0.0001 20.7 14.8 0.42 8.8 0.2 5.4 2 1 3 6 6 6 4 Cytochrome D1 heme domain Pentapeptide_4 PF13599.1 ETO12363.1 - 0.00055 19.6 0.3 0.0015 18.3 0.2 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) DUF3732 PF12532.3 ETO12363.1 - 0.0022 17.5 7.6 15 5.0 0.0 7.5 4 3 6 10 10 10 0 Protein of unknown function (DUF3732) Pentapeptide PF00805.17 ETO12363.1 - 0.0048 16.1 1.5 0.0094 15.1 1.0 1.4 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) DUF727 PF05303.7 ETO12363.1 - 0.011 15.4 2.6 70 3.2 0.0 6.3 7 1 0 7 7 7 0 Protein of unknown function (DUF727) Pentapeptide_3 PF13576.1 ETO12363.1 - 0.019 14.8 3.5 0.056 13.3 2.4 1.8 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) DUF2684 PF10885.3 ETO12363.1 - 0.063 13.1 0.1 0.64 9.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2684) Pkinase PF00069.20 ETO12367.1 - 3.5e-20 72.2 0.0 4.4e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO12367.1 - 6.1e-08 32.0 0.0 2e-07 30.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase NTP_transf_2 PF01909.18 ETO12369.1 - 0.00022 21.4 0.0 0.00034 20.8 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain V-set PF07686.12 ETO12370.1 - 0.24 11.2 1.8 0.35 10.7 0.2 2.0 2 0 0 2 2 2 0 Immunoglobulin V-set domain LRR_4 PF12799.2 ETO12371.1 - 4e-09 35.8 11.4 0.023 14.3 0.2 7.5 5 2 3 8 8 8 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 ETO12371.1 - 1.9e-07 30.4 5.5 0.92 9.7 0.1 7.4 10 0 0 10 10 10 3 Leucine Rich repeat LRR_1 PF00560.28 ETO12371.1 - 0.00035 20.1 9.1 9.5 6.7 0.0 8.5 10 0 0 10 10 10 1 Leucine Rich Repeat LRR_8 PF13855.1 ETO12371.1 - 0.00068 19.3 15.2 0.013 15.2 0.2 6.5 6 2 0 7 7 7 1 Leucine rich repeat LRR_7 PF13504.1 ETO12371.1 - 0.002 18.0 2.7 13 6.5 0.0 7.1 8 0 0 8 8 8 1 Leucine rich repeat 7kD_coat PF02495.12 ETO12371.1 - 0.25 10.8 3.8 16 5.0 0.0 3.8 4 0 0 4 4 4 0 7kD viral coat protein U3_assoc_6 PF08640.6 ETO12374.1 - 5.5e-06 26.0 2.6 5.5e-06 26.0 1.8 2.4 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 TPR_17 PF13431.1 ETO12374.1 - 0.064 13.4 2.8 33 5.0 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4480 PF13715.1 ETO12375.1 - 0.014 15.4 0.7 0.032 14.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4480) Transthyretin PF00576.16 ETO12375.1 - 0.026 14.4 0.0 0.071 13.0 0.0 1.7 1 0 0 1 1 1 0 HIUase/Transthyretin family FadA PF09403.5 ETO12375.1 - 0.1 12.6 2.0 1 9.4 0.3 2.6 2 0 0 2 2 2 0 Adhesion protein FadA TPR_1 PF00515.23 ETO12376.1 - 3.3e-64 210.0 31.8 8.8e-08 31.4 0.0 9.2 8 1 1 9 9 9 9 Tetratricopeptide repeat TPR_11 PF13414.1 ETO12376.1 - 5.1e-62 205.4 28.4 1e-15 57.0 2.8 5.1 3 1 2 5 5 5 5 TPR repeat TPR_17 PF13431.1 ETO12376.1 - 2.2e-61 199.0 22.7 8.2e-09 34.9 0.2 8.7 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 ETO12376.1 - 2.4e-59 192.5 24.8 4e-07 29.4 0.0 8.9 8 1 1 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.1 ETO12376.1 - 2.1e-55 184.5 37.8 4.7e-11 42.4 0.9 6.1 1 1 6 7 7 7 7 Tetratricopeptide repeat TPR_16 PF13432.1 ETO12376.1 - 2.4e-45 152.3 17.6 6e-10 39.5 0.5 6.0 2 2 4 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETO12376.1 - 1.8e-44 146.2 27.6 2.1e-05 23.9 0.0 9.3 7 2 2 9 9 9 8 Tetratricopeptide repeat TPR_14 PF13428.1 ETO12376.1 - 7.7e-43 141.0 7.3 1e-05 25.7 0.0 8.7 1 1 7 8 8 8 7 Tetratricopeptide repeat TPR_19 PF14559.1 ETO12376.1 - 1.6e-36 124.4 44.1 3.8e-09 36.7 3.5 5.2 2 1 4 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.1 ETO12376.1 - 1.9e-25 86.5 11.8 0.032 14.0 0.0 8.5 8 1 0 8 8 8 7 Tetratricopeptide repeat TPR_6 PF13174.1 ETO12376.1 - 2.1e-16 59.1 10.2 0.27 11.7 0.0 8.2 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_4 PF07721.9 ETO12376.1 - 2.2e-15 55.4 0.2 0.45 11.0 0.0 7.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETO12376.1 - 5e-15 55.1 0.8 0.0053 16.5 0.1 5.2 1 1 3 5 5 5 4 Tetratricopeptide repeat NARP1 PF12569.3 ETO12376.1 - 1.6e-11 43.6 7.5 0.021 13.5 0.0 4.3 1 1 5 6 6 6 6 NMDA receptor-regulated protein 1 TPR_10 PF13374.1 ETO12376.1 - 5.3e-10 38.8 14.9 0.84 9.6 0.1 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat FliD_C PF07195.7 ETO12376.1 - 3.7e-09 36.2 2.0 0.039 13.2 0.2 5.4 1 1 4 5 5 5 3 Flagellar hook-associated protein 2 C-terminus Fis1_TPR_C PF14853.1 ETO12376.1 - 6e-09 35.6 24.8 0.52 10.2 0.1 7.8 4 2 4 8 8 8 4 Fis1 C-terminal tetratricopeptide repeat EST1_DNA_bind PF10373.4 ETO12376.1 - 2.8e-05 23.4 4.5 0.76 8.9 0.1 5.0 4 2 2 6 6 6 2 Est1 DNA/RNA binding domain TOM20_plant PF06552.7 ETO12376.1 - 0.00018 21.1 6.7 1.1 8.8 0.0 5.2 1 1 4 5 5 5 1 Plant specific mitochondrial import receptor subunit TOM20 PPTA PF01239.17 ETO12376.1 - 0.00041 19.5 18.0 8.7 5.8 0.0 7.7 8 0 0 8 8 8 0 Protein prenyltransferase alpha subunit repeat FAT PF02259.18 ETO12376.1 - 0.0016 17.4 7.6 0.51 9.2 0.6 5.2 1 1 3 4 4 4 1 FAT domain CryBP1 PF07029.6 ETO12376.1 - 0.0028 17.4 1.8 4.5 6.9 0.1 4.5 1 1 2 4 4 4 1 CryBP1 protein B_lectin PF01453.19 ETO12376.1 - 0.0043 16.9 0.5 3.9 7.4 0.0 3.3 1 1 1 3 3 3 1 D-mannose binding lectin Alkyl_sulf_dimr PF14863.1 ETO12376.1 - 0.005 17.0 13.4 1.5 9.0 0.1 5.4 1 1 6 7 7 7 1 Alkyl sulfatase dimerisation DUF2803 PF10972.3 ETO12376.1 - 0.011 15.2 4.1 2 7.8 0.0 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2803) DUF2155 PF09923.4 ETO12376.1 - 0.013 15.5 0.8 6.9 6.8 0.0 3.4 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2155) DUF1547 PF07577.6 ETO12376.1 - 0.017 14.7 4.7 10 5.8 0.0 5.2 5 2 1 6 6 6 0 Domain of Unknown Function (DUF1547) Hemocyanin_C PF03723.9 ETO12376.1 - 0.13 11.3 0.0 11 5.1 0.0 3.3 3 1 1 4 4 4 0 Hemocyanin, ig-like domain HemolysinCabind PF00353.14 ETO12377.1 - 2.7e-31 104.8 273.8 0.0019 18.4 1.4 30.6 24 4 4 34 34 34 24 Hemolysin-type calcium-binding repeat (2 copies) Ribosomal_S5 PF00333.15 ETO12377.1 - 0.017 14.8 1.7 0.043 13.5 1.2 1.7 1 0 0 1 1 1 0 Ribosomal protein S5, N-terminal domain DUF4094 PF13334.1 ETO12378.1 - 0.17 12.3 0.1 0.17 12.3 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) DUF2207 PF09972.4 ETO12379.1 - 6.9 5.1 8.4 1.5 7.3 0.5 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) WD40 PF00400.27 ETO12380.1 - 6.2e-25 86.1 6.5 5.4e-09 35.6 0.1 3.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO12380.1 - 0.022 12.9 0.1 0.25 9.4 0.0 2.0 1 1 0 2 2 2 0 Nucleoporin Nup120/160 WD40 PF00400.27 ETO12381.1 - 2.6e-59 195.1 17.7 1.9e-11 43.3 0.4 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO12381.1 - 3.8e-07 28.6 5.7 0.075 11.1 0.1 4.5 1 1 3 4 4 4 3 Nucleoporin Nup120/160 PD40 PF07676.7 ETO12381.1 - 0.00083 18.9 3.5 1.7 8.3 0.3 3.8 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO12381.1 - 0.019 13.3 0.2 2.6 6.2 0.0 2.4 2 0 0 2 2 2 0 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO12381.1 - 0.02 14.3 1.5 0.79 9.1 0.8 2.7 1 1 2 3 3 3 0 PQQ-like domain Sulfotransfer_3 PF13469.1 ETO12382.1 - 1.7e-12 48.5 4.4 2.4e-11 44.8 2.6 2.3 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 ETO12382.1 - 1.8e-09 37.2 5.3 1.8e-09 37.2 3.7 3.3 1 1 2 3 3 2 2 Sulfotransferase domain Ctr PF04145.10 ETO12382.1 - 0.057 13.4 3.8 0.1 12.6 1.1 2.5 2 0 0 2 2 2 0 Ctr copper transporter family DUF2201_N PF13203.1 ETO12382.1 - 0.074 12.2 8.9 0.12 11.5 6.2 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Mem_trans PF03547.13 ETO12382.1 - 0.095 10.9 4.3 0.15 10.3 3.0 1.2 1 0 0 1 1 1 0 Membrane transport protein Neur_chan_memb PF02932.11 ETO12382.1 - 0.11 12.3 8.3 0.22 11.3 5.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LMBR1 PF04791.11 ETO12382.1 - 0.23 10.0 1.8 0.34 9.4 1.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Zip PF02535.17 ETO12382.1 - 0.37 9.7 1.2 0.51 9.3 0.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Ndc1_Nup PF09531.5 ETO12382.1 - 0.57 8.5 4.3 1.1 7.5 3.0 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Gti1_Pac2 PF09729.4 ETO12382.1 - 0.71 9.7 11.0 1.4 8.7 7.6 1.5 1 0 0 1 1 1 0 Gti1/Pac2 family DUF908 PF06012.7 ETO12382.1 - 1.1 8.4 7.8 2.3 7.4 3.6 2.2 2 1 0 2 2 2 0 Domain of Unknown Function (DUF908) Med19 PF10278.4 ETO12382.1 - 1.2 8.7 19.7 0.054 13.1 9.6 1.7 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 CDC45 PF02724.9 ETO12382.1 - 3.9 5.4 14.8 5.7 4.8 10.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Serinc PF03348.10 ETO12382.1 - 4.6 5.8 5.6 6.7 5.3 3.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) YqfQ PF14181.1 ETO12382.1 - 7.7 6.5 18.9 14 5.6 13.1 1.4 1 0 0 1 1 1 0 YqfQ-like protein ETRAMP PF09716.5 ETO12382.1 - 8.4 6.4 9.2 29 4.6 6.4 1.9 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) NDUF_C2 PF06374.6 ETO12383.1 - 0.0038 17.2 1.5 0.028 14.4 0.0 2.3 1 1 0 2 2 2 1 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) Use1 PF09753.4 ETO12383.1 - 0.0071 15.8 11.1 0.0071 15.8 7.7 1.4 1 1 0 1 1 1 1 Membrane fusion protein Use1 Mt_ATP-synt_B PF05405.9 ETO12383.1 - 0.088 12.2 9.9 0.16 11.3 6.9 1.5 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF4407 PF14362.1 ETO12383.1 - 1.2 7.9 8.8 1.9 7.3 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SUI1 PF01253.17 ETO12384.1 - 1e-16 60.5 2.9 1.2e-16 60.2 2.0 1.0 1 0 0 1 1 1 1 Translation initiation factor SUI1 cNMP_binding PF00027.24 ETO12385.1 - 1.1e-09 37.9 0.0 1.9e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain SMC_N PF02463.14 ETO12386.1 - 0.0096 15.1 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF3035 PF11233.3 ETO12387.1 - 0.007 16.4 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3035) Metallophos PF00149.23 ETO12388.1 - 1.5e-09 37.5 0.8 1.9e-08 33.9 0.0 2.0 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase DUF3357 PF11837.3 ETO12389.1 - 0.0031 17.3 0.0 0.0031 17.3 0.0 3.5 1 1 2 3 3 2 1 Domain of unknown function (DUF3357) DUF1510 PF07423.6 ETO12389.1 - 0.0052 16.1 24.0 0.0052 16.1 16.6 2.3 1 1 1 2 2 1 1 Protein of unknown function (DUF1510) ESSS PF10183.4 ETO12389.1 - 0.037 14.4 0.1 0.037 14.4 0.0 3.2 1 1 1 2 2 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) PBP1_TM PF14812.1 ETO12389.1 - 0.049 13.9 0.1 0.049 13.9 0.1 4.7 2 2 3 5 5 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal 7TM_GPCR_Srd PF10317.4 ETO12389.1 - 0.055 12.4 0.2 0.49 9.3 0.0 2.2 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srd Transformer PF06495.6 ETO12389.1 - 0.23 11.3 43.6 0.41 10.5 9.0 2.3 2 0 0 2 2 2 0 Fruit fly transformer protein Baculo_11_kDa PF06143.6 ETO12389.1 - 1.8 7.9 8.7 0.15 11.4 0.2 3.0 2 1 0 3 3 3 0 Baculovirus 11 kDa family Macoilin PF09726.4 ETO12389.1 - 2.6 6.2 41.6 3.9 5.6 28.9 1.2 1 0 0 1 1 1 0 Transmembrane protein CDC45 PF02724.9 ETO12389.1 - 2.9 5.8 47.3 0.93 7.4 14.0 2.0 2 0 0 2 2 2 0 CDC45-like protein DUF3984 PF13136.1 ETO12389.1 - 2.9 7.0 36.2 0.98 8.5 11.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3984) BatD PF13584.1 ETO12389.1 - 4.8 5.6 20.4 0.011 14.3 5.5 2.4 1 1 2 3 3 3 0 Oxygen tolerance SpoIIIAH PF12685.2 ETO12389.1 - 5.5 6.4 31.3 0.023 14.1 3.3 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein SID-1_RNA_chan PF13965.1 ETO12389.1 - 5.9 4.9 23.6 0.38 8.8 12.6 1.8 1 1 1 2 2 2 0 dsRNA-gated channel SID-1 MIP-T3 PF10243.4 ETO12389.1 - 6.5 5.0 69.7 10 4.4 48.3 1.2 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 PH PF00169.24 ETO12390.1 - 1.3e-19 70.2 13.8 2e-12 47.2 0.1 3.5 3 1 0 3 3 3 3 PH domain PH_11 PF15413.1 ETO12390.1 - 4.1e-09 36.6 19.5 0.001 19.2 2.2 4.7 4 1 0 4 4 4 3 Pleckstrin homology domain PH_8 PF15409.1 ETO12390.1 - 5.3e-08 32.8 9.7 0.0015 18.5 0.1 3.8 3 1 1 4 4 4 3 Pleckstrin homology domain PH_3 PF14593.1 ETO12390.1 - 5.4e-06 26.2 4.9 0.61 9.9 0.1 4.4 2 1 1 3 3 3 3 PH domain PH_4 PF15404.1 ETO12390.1 - 0.059 12.8 7.4 0.21 11.1 0.0 3.5 4 0 0 4 4 4 0 Pleckstrin homology domain Mcp5_PH PF12814.2 ETO12390.1 - 0.72 9.7 6.8 0.5 10.2 0.8 2.9 2 1 1 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology DUF848 PF05852.6 ETO12391.1 - 0.54 10.0 8.9 0.48 10.2 4.2 2.1 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF1003 PF06210.6 ETO12391.1 - 0.69 9.8 3.4 1 9.3 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1003) WD40 PF00400.27 ETO12393.1 - 5.9e-22 76.6 6.9 1.9e-09 37.0 0.1 5.1 5 1 0 5 5 5 3 WD domain, G-beta repeat VWA_2 PF13519.1 ETO12394.1 - 3.3e-06 27.3 0.0 3.9e-06 27.0 0.0 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 ETO12394.1 - 0.00016 21.4 0.0 0.0002 21.1 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 ETO12394.1 - 0.00086 19.0 0.0 0.0011 18.7 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain WBP-1 PF11669.3 ETO12394.1 - 0.62 10.1 4.2 1.1 9.3 2.9 1.3 1 0 0 1 1 1 0 WW domain-binding protein 1 DUF1053 PF06327.9 ETO12396.1 - 0.0058 16.9 5.4 0.0058 16.9 3.8 2.0 2 1 0 2 2 2 1 Domain of Unknown Function (DUF1053) LuxC PF05893.9 ETO12396.1 - 0.019 13.6 1.3 0.031 13.0 0.9 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) ArsC PF03960.10 ETO12396.1 - 0.074 13.1 1.5 0.094 12.7 0.1 1.9 2 0 0 2 2 2 0 ArsC family AF0941-like PF14591.1 ETO12396.1 - 0.38 10.8 9.3 0.056 13.4 2.3 2.5 3 1 1 4 4 4 0 AF0941-like Serpin PF00079.15 ETO12398.1 - 3.6e-18 65.8 0.1 2.9e-11 43.1 0.0 2.1 2 0 0 2 2 2 2 Serpin (serine protease inhibitor) AF1Q PF15017.1 ETO12399.1 - 0.2 11.5 2.9 0.63 9.9 2.0 1.9 1 1 0 1 1 1 0 Drug resistance and apoptosis regulator PBP1_TM PF14812.1 ETO12399.1 - 0.9 9.8 6.0 2 8.8 4.2 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HlyIII PF03006.15 ETO12400.1 - 2.7e-06 26.9 2.4 3.3e-06 26.6 1.6 1.2 1 0 0 1 1 1 1 Haemolysin-III related HlyIII PF03006.15 ETO12401.1 - 1.1e-10 41.2 14.5 1.6e-10 40.8 10.0 1.2 1 0 0 1 1 1 1 Haemolysin-III related RtcB PF01139.12 ETO12402.1 - 8.3e-85 285.2 0.0 2.1e-50 171.9 0.0 2.4 2 1 1 3 3 3 2 tRNA-splicing ligase RtcB Daxx PF03344.10 ETO12402.1 - 2.6e-06 26.2 17.8 3.9e-06 25.6 12.3 1.3 1 0 0 1 1 1 1 Daxx Family Utp14 PF04615.8 ETO12402.1 - 0.16 10.0 29.3 0.29 9.2 20.3 1.3 1 0 0 1 1 1 0 Utp14 protein TFIIF_alpha PF05793.7 ETO12402.1 - 4 5.6 37.3 6.7 4.9 25.8 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Hid1 PF12722.2 ETO12402.1 - 5.9 4.4 17.6 7.9 4.0 12.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2413 PF10310.4 ETO12403.1 - 0.28 9.9 26.6 0.35 9.6 18.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Zip PF02535.17 ETO12403.1 - 3.3 6.6 7.3 3.6 6.5 5.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SR-25 PF10500.4 ETO12403.1 - 4.6 6.6 31.1 5 6.5 21.1 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein SSP160 PF06933.6 ETO12403.1 - 6 4.7 6.9 7.5 4.3 4.8 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 WD40 PF00400.27 ETO12405.1 - 4.2e-56 184.9 23.9 4e-11 42.3 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO12405.1 - 1.7e-11 42.9 6.4 0.00032 18.9 0.0 5.5 1 1 3 6 6 6 6 Nucleoporin Nup120/160 Plasmid_parti PF01672.11 ETO12406.1 - 0.024 15.0 3.1 0.024 15.0 2.2 2.2 2 0 0 2 2 2 0 Putative plasmid partition protein Synaptobrevin PF00957.16 ETO12406.1 - 1.1 8.9 4.5 4.7 6.8 0.9 2.3 2 0 0 2 2 2 0 Synaptobrevin DUF3461 PF11944.3 ETO12407.1 - 0.0069 16.2 1.3 0.0069 16.2 0.9 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3461) Ribosomal_S7 PF00177.16 ETO12407.1 - 0.25 10.9 7.1 0.51 9.9 0.4 2.3 2 0 0 2 2 2 0 Ribosomal protein S7p/S5e Nup54 PF13874.1 ETO12407.1 - 5.8 6.5 11.5 1.4 8.5 3.5 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Terminase_4 PF05119.7 ETO12408.1 - 0.031 14.4 0.1 0.065 13.3 0.0 1.7 2 0 0 2 2 2 0 Phage terminase, small subunit DUF2053 PF09767.4 ETO12408.1 - 0.12 12.4 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2053) Proteasome PF00227.21 ETO12409.1 - 1.5e-24 86.3 0.2 3.2e-22 78.7 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit DUF3440 PF11922.3 ETO12409.1 - 0.097 12.2 1.2 0.15 11.6 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3440) OTU PF02338.14 ETO12410.1 - 1.2e-05 25.8 1.2 2.2e-05 25.0 0.3 1.8 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 ETO12410.1 - 0.0021 17.4 0.1 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase C65 Otubain SH3_9 PF14604.1 ETO12410.1 - 0.0042 16.6 0.2 2 8.0 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain AAA_12 PF13087.1 ETO12414.1 - 1.5e-07 30.9 0.0 1.2e-06 28.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain RAP PF08373.5 ETO12414.1 - 0.0091 15.7 0.2 0.022 14.5 0.1 1.6 1 0 0 1 1 1 1 RAP domain DUF559 PF04480.7 ETO12414.1 - 0.021 14.4 0.1 0.051 13.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF559) HlyD PF00529.15 ETO12416.1 - 0.0085 15.4 9.1 0.011 15.1 6.3 1.1 1 0 0 1 1 1 1 HlyD family secretion protein RRF PF01765.14 ETO12416.1 - 0.019 14.4 8.4 0.032 13.7 5.8 1.3 1 0 0 1 1 1 0 Ribosome recycling factor HsbA PF12296.3 ETO12416.1 - 0.1 12.4 5.9 4.3 7.2 0.6 2.6 1 1 2 3 3 3 0 Hydrophobic surface binding protein A Vfa1 PF08432.5 ETO12416.1 - 0.11 12.5 8.8 0.15 12.0 6.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RE_AlwI PF09491.5 ETO12416.1 - 0.12 10.8 8.9 0.15 10.5 6.1 1.1 1 0 0 1 1 1 0 AlwI restriction endonuclease zf-RING_UBOX PF13445.1 ETO12416.1 - 0.12 12.0 0.0 0.34 10.6 0.0 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Atg14 PF10186.4 ETO12416.1 - 0.14 11.0 8.0 0.19 10.6 5.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Lebercilin PF15619.1 ETO12416.1 - 0.23 10.8 15.2 2 7.7 8.7 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Peptidase_C6 PF00851.13 ETO12416.1 - 0.29 9.7 4.9 0.34 9.4 3.4 1.1 1 0 0 1 1 1 0 Helper component proteinase APG6 PF04111.7 ETO12416.1 - 0.53 9.2 10.7 0.72 8.8 7.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4407 PF14362.1 ETO12416.1 - 2.7 6.8 6.1 4 6.2 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Jnk-SapK_ap_N PF09744.4 ETO12417.1 - 0.02 14.8 3.0 0.02 14.8 2.1 2.6 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 Fib_alpha PF08702.5 ETO12417.1 - 0.034 14.2 22.0 0.042 13.9 14.0 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Reo_sigmaC PF04582.7 ETO12417.1 - 0.037 13.2 2.2 0.46 9.6 1.5 1.8 1 1 0 1 1 1 0 Reovirus sigma C capsid protein TylF PF05711.6 ETO12417.1 - 0.043 12.8 4.1 0.072 12.1 0.2 2.0 1 1 1 2 2 2 0 Macrocin-O-methyltransferase (TylF) IncA PF04156.9 ETO12417.1 - 0.26 10.8 32.2 0.63 9.5 4.6 2.1 1 1 1 2 2 2 0 IncA protein ERM PF00769.14 ETO12417.1 - 0.37 10.2 27.3 1.7 8.0 19.0 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Prefoldin PF02996.12 ETO12417.1 - 0.6 9.7 20.6 0.07 12.7 2.2 3.1 2 1 1 3 3 3 0 Prefoldin subunit Omp28 PF11551.3 ETO12417.1 - 0.72 9.3 3.0 0.82 9.1 0.9 1.7 1 1 1 2 2 2 0 Outer membrane protein Omp28 Atg14 PF10186.4 ETO12417.1 - 0.9 8.4 23.6 1.6 7.5 16.4 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 COG2 PF06148.6 ETO12417.1 - 1.7 8.5 13.1 2.2 8.1 1.6 2.4 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3735 PF12537.3 ETO12417.1 - 2.9 8.0 9.1 0.83 9.7 0.2 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3735) Synaptobrevin PF00957.16 ETO12417.1 - 4.2 7.0 11.0 0.65 9.6 4.5 1.9 1 1 2 3 3 3 0 Synaptobrevin GAS PF13851.1 ETO12417.1 - 4.5 6.4 28.5 5.2 6.1 14.6 2.1 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Pox_A_type_inc PF04508.7 ETO12417.1 - 6.2 6.8 13.6 21 5.2 1.3 4.8 3 1 2 5 5 5 0 Viral A-type inclusion protein repeat FliD_N PF02465.13 ETO12417.1 - 7 7.0 16.9 1.6 9.1 1.6 2.3 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus AAA_23 PF13476.1 ETO12417.1 - 8.4 6.6 23.4 15 5.8 16.2 1.4 1 0 0 1 1 1 0 AAA domain zf-CCHC PF00098.18 ETO12418.1 - 0.0012 18.6 9.3 0.0062 16.4 1.6 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 ETO12418.1 - 0.26 11.0 9.1 1.4 8.7 5.5 2.5 1 1 1 2 2 2 0 Zinc knuckle CIA30 PF08547.7 ETO12419.1 - 1.2e-16 61.0 0.0 2e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) DUF524 PF04411.7 ETO12420.1 - 0.065 13.0 0.1 0.11 12.3 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF524) Glyco_hydro_67N PF03648.9 ETO12421.1 - 0.012 15.6 0.5 0.019 14.9 0.4 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 N-terminus DUF106 PF01956.11 ETO12421.1 - 0.02 14.4 0.8 0.035 13.6 0.6 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF3210 PF11489.3 ETO12421.1 - 0.42 9.2 5.9 0.52 8.9 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3210) Biotin_carb_C PF02785.14 ETO12422.1 - 8.6e-34 115.7 0.0 7.1e-33 112.8 0.0 2.3 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain CPSase_L_D2 PF02786.12 ETO12422.1 - 2.8e-23 82.3 0.0 5.5e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Spc7 PF08317.6 ETO12423.1 - 0.03 13.0 32.3 0.24 10.0 8.6 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein EzrA PF06160.7 ETO12423.1 - 0.039 12.1 27.2 18 3.3 18.8 2.1 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA PEP-utilisers_N PF05524.8 ETO12423.1 - 1.9 8.2 7.5 1.2 8.9 0.4 2.7 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal TPR_MLP1_2 PF07926.7 ETO12423.1 - 2 8.1 38.7 0.98 9.1 6.7 3.0 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 ETO12423.1 - 2.5 7.1 4.4 8.4 5.4 0.2 2.1 1 1 0 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 ETO12423.1 - 3.4 7.2 37.4 5.6 6.5 12.4 2.1 1 1 1 2 2 2 0 IncA protein DUF1664 PF07889.7 ETO12423.1 - 9.5 6.0 16.2 5.2 6.8 2.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF3611 PF12263.3 ETO12424.1 - 0.033 13.5 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) DUF4414 PF14377.1 ETO12425.1 - 0.017 15.0 0.0 0.034 14.0 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4414) DUF4200 PF13863.1 ETO12425.1 - 0.018 14.9 2.2 0.018 14.9 1.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Sas10_Utp3 PF04000.10 ETO12425.1 - 0.032 14.4 2.2 0.038 14.1 0.2 1.9 2 0 0 2 2 2 0 Sas10/Utp3/C1D family zf-3CxxC PF13695.1 ETO12425.1 - 0.2 11.8 2.0 0.3 11.3 0.5 1.8 2 0 0 2 2 2 0 Zinc-binding domain RRM_6 PF14259.1 ETO12426.1 - 0.0013 18.6 0.0 0.0055 16.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO12426.1 - 0.0028 17.2 0.0 0.0049 16.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO12426.1 - 0.028 14.2 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RR_TM4-6 PF06459.7 ETO12426.1 - 3.5 7.4 8.7 5.4 6.8 6.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mob1_phocein PF03637.12 ETO12429.1 - 3.5e-08 33.3 0.2 0.0028 17.3 0.2 2.6 2 0 0 2 2 2 2 Mob1/phocein family RIH_assoc PF08454.6 ETO12429.1 - 0.0089 15.6 0.6 0.0089 15.6 0.4 2.0 2 0 0 2 2 2 1 RyR and IP3R Homology associated RAP1 PF07218.6 ETO12430.1 - 0.29 9.1 4.2 0.42 8.6 2.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SR-25 PF10500.4 ETO12430.1 - 0.82 9.0 4.7 1.7 8.0 3.3 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pilt PF15453.1 ETO12430.1 - 3.1 7.3 6.8 6 6.4 4.7 1.4 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions FLYWCH PF04500.11 ETO12430.1 - 7.3 6.5 8.9 1 9.2 2.0 2.7 2 1 1 3 3 3 0 FLYWCH zinc finger domain DLIC PF05783.6 ETO12431.1 - 0.063 11.9 0.5 0.085 11.5 0.3 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) PRTase_2 PF15609.1 ETO12431.1 - 0.064 12.5 0.1 0.095 11.9 0.1 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase GTP_EFTU PF00009.22 ETO12432.1 - 2e-23 82.7 0.0 2.8e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 ETO12432.1 - 1e-06 28.6 0.2 0.0011 18.8 0.0 2.4 2 0 0 2 2 2 2 Dynamin family Miro PF08477.8 ETO12432.1 - 1.6e-05 25.3 0.1 9.4e-05 22.8 0.0 2.3 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 ETO12432.1 - 5e-05 23.2 0.1 0.00019 21.3 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETO12432.1 - 0.0015 17.8 0.1 0.013 14.8 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B NOG1 PF06858.9 ETO12432.1 - 0.029 14.2 0.2 0.085 12.7 0.1 1.8 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) ZYG-11_interact PF05884.7 ETO12432.1 - 0.074 12.1 0.1 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 AAA_14 PF13173.1 ETO12432.1 - 0.075 12.9 0.1 9.1 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain WD40 PF00400.27 ETO12435.1 - 1.4e-58 192.8 23.1 1.4e-11 43.7 0.3 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO12435.1 - 1.9e-07 29.6 5.6 0.84 7.6 0.1 5.8 3 3 2 5 5 5 4 Nucleoporin Nup120/160 Cytomega_UL84 PF06284.6 ETO12435.1 - 0.091 11.1 2.1 0.16 10.3 1.5 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Vfa1 PF08432.5 ETO12435.1 - 0.56 10.2 12.8 0.81 9.6 8.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NARP1 PF12569.3 ETO12435.1 - 3.1 6.4 10.8 4.4 5.9 7.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 eRF1_2 PF03464.10 ETO12436.1 - 1e-43 148.8 0.0 2.1e-43 147.8 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 ETO12436.1 - 8e-31 106.6 0.1 2.3e-30 105.1 0.0 1.7 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 ETO12436.1 - 1.9e-24 85.7 0.0 3.4e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 Ribosomal_L7Ae PF01248.21 ETO12436.1 - 0.00038 19.9 0.0 0.0008 18.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF3388 PF11868.3 ETO12436.1 - 0.069 12.2 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3388) DUF2215 PF10225.4 ETO12437.1 - 1.3 8.3 5.1 0.43 9.9 0.9 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) FHA PF00498.21 ETO12439.1 - 0.016 15.3 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 FHA domain ATAD4 PF15321.1 ETO12439.1 - 0.38 11.7 6.2 1.5 9.9 1.4 2.3 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 WD40 PF00400.27 ETO12440.1 - 0.046 13.6 0.0 0.96 9.4 0.0 2.2 2 0 0 2 2 2 0 WD domain, G-beta repeat B56 PF01603.15 ETO12441.1 - 8.6e-23 80.5 0.6 1e-22 80.3 0.4 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Urocanase PF01175.13 ETO12442.1 - 5.5e-17 61.0 0.0 2e-16 59.1 0.0 1.7 1 1 1 2 2 2 1 Urocanase tRNA_lig_CPD PF08302.6 ETO12442.1 - 0.00054 19.2 0.6 0.00062 19.0 0.4 1.1 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain ATP11 PF06644.6 ETO12442.1 - 0.0017 17.8 0.1 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 ATP11 protein LCD1 PF09798.4 ETO12442.1 - 0.0061 14.6 0.9 0.0072 14.3 0.6 1.0 1 0 0 1 1 1 1 DNA damage checkpoint protein DUF3641 PF12345.3 ETO12442.1 - 0.043 13.6 1.5 0.07 12.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3641) Urocanase PF01175.13 ETO12443.1 - 1.7e-130 435.6 3.3 1.6e-116 389.5 0.2 2.0 2 0 0 2 2 2 2 Urocanase NAF PF03822.9 ETO12444.1 - 0.0098 15.5 0.1 0.035 13.8 0.1 1.9 1 0 0 1 1 1 1 NAF domain Tubulin PF00091.20 ETO12445.1 - 1.3e-71 240.8 0.0 2.2e-71 240.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO12445.1 - 4.2e-35 120.5 0.0 8.9e-35 119.4 0.0 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 ETO12445.1 - 2.4e-06 27.5 0.0 5.7e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 ETO12445.1 - 0.11 12.0 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Sfi1 PF08457.5 ETO12446.1 - 0.00021 19.8 9.9 0.00021 19.8 6.8 4.1 1 1 3 5 5 5 4 Sfi1 spindle body protein PsiE PF06146.7 ETO12446.1 - 0.049 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Phosphate-starvation-inducible E 4HB_MCP_1 PF12729.2 ETO12446.1 - 4 6.7 8.9 6.9 5.9 1.3 2.7 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction Sfi1 PF08457.5 ETO12447.1 - 0.0012 17.3 35.7 0.017 13.5 17.0 2.2 1 1 1 2 2 2 2 Sfi1 spindle body protein SUI1 PF01253.17 ETO12449.1 - 0.037 13.8 1.1 1.1 9.1 0.0 3.4 4 0 0 4 4 4 0 Translation initiation factor SUI1 DUF3355 PF11835.3 ETO12450.1 - 0.011 15.5 0.3 0.011 15.5 0.2 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF3355) CENP-F_leu_zip PF10473.4 ETO12450.1 - 0.022 14.6 35.1 0.051 13.4 6.4 3.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Nup54 PF13874.1 ETO12450.1 - 0.47 10.1 27.2 0.42 10.2 4.9 2.4 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 DUF342 PF03961.8 ETO12450.1 - 0.73 8.1 28.1 0.026 12.9 6.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Hid1 PF12722.2 ETO12450.1 - 1.3 6.5 24.9 1.7 6.1 17.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein IncA PF04156.9 ETO12450.1 - 2.4 7.6 41.7 1.3 8.5 14.0 2.1 1 1 0 2 2 2 0 IncA protein AAA_13 PF13166.1 ETO12450.1 - 4.2 5.7 36.2 0.11 11.0 7.3 2.5 1 1 1 2 2 2 0 AAA domain Zip PF02535.17 ETO12450.1 - 6.1 5.7 11.1 0.13 11.2 2.9 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter Arf PF00025.16 ETO12451.1 - 4.6e-42 143.1 0.0 5.6e-42 142.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 ETO12451.1 - 1.2e-10 40.9 0.0 1.5e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 ETO12451.1 - 1.9e-10 40.0 0.8 7e-08 31.5 0.2 2.8 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 ETO12451.1 - 1.9e-09 37.4 0.0 2.7e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 ETO12451.1 - 2.5e-09 37.6 0.0 3.9e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 ETO12451.1 - 7.8e-08 31.9 0.0 1e-06 28.3 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 ETO12451.1 - 2.2e-06 26.9 0.0 2.7e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 ETO12451.1 - 0.00012 21.3 0.0 0.00016 20.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 ETO12451.1 - 0.07 12.6 0.1 0.33 10.4 0.0 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 ETO12451.1 - 0.094 13.5 0.0 0.18 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 ETO12451.1 - 0.14 11.8 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF1510 PF07423.6 ETO12452.1 - 0.045 13.1 10.2 0.05 12.9 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Menin PF05053.8 ETO12452.1 - 0.11 10.6 9.2 0.13 10.4 6.4 1.0 1 0 0 1 1 1 0 Menin Neur_chan_memb PF02932.11 ETO12452.1 - 0.15 11.9 4.7 0.17 11.7 3.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CPSF100_C PF13299.1 ETO12452.1 - 0.24 11.5 7.1 0.29 11.3 4.9 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal NOA36 PF06524.7 ETO12452.1 - 0.27 10.4 8.5 0.34 10.1 5.9 1.1 1 0 0 1 1 1 0 NOA36 protein Ebola_NP PF05505.7 ETO12452.1 - 0.52 8.3 10.0 0.63 8.0 6.9 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein CDC45 PF02724.9 ETO12452.1 - 0.66 7.9 7.9 0.69 7.8 5.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.4 ETO12452.1 - 1.1 7.4 12.1 1.2 7.2 8.4 1.0 1 0 0 1 1 1 0 Transmembrane protein Peptidase_S64 PF08192.6 ETO12452.1 - 1.5 7.0 10.9 1.8 6.8 7.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 Mem_trans PF03547.13 ETO12452.1 - 1.6 6.9 3.7 1.7 6.8 2.6 1.1 1 0 0 1 1 1 0 Membrane transport protein Hid1 PF12722.2 ETO12452.1 - 1.7 6.2 13.1 1.8 6.1 9.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Clp1 PF06807.9 ETO12453.1 - 3.5e-12 46.4 1.0 1.3e-11 44.5 0.7 2.1 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 Y_phosphatase2 PF03162.8 ETO12454.1 - 4.9e-16 58.5 0.0 2.4e-14 53.0 0.0 2.4 2 0 0 2 2 2 1 Tyrosine phosphatase family Zip PF02535.17 ETO12454.1 - 0.028 13.4 2.5 0.028 13.4 1.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Dzip-like_N PF13815.1 ETO12454.1 - 0.07 12.9 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal EamA PF00892.15 ETO12455.1 - 0.00044 20.3 8.5 0.002 18.1 6.3 1.7 2 0 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 ETO12455.1 - 0.0021 18.2 11.2 0.0033 17.6 7.8 1.3 1 0 0 1 1 1 1 Multidrug resistance efflux transporter UAA PF08449.6 ETO12455.1 - 0.046 12.6 4.3 0.063 12.1 3.0 1.2 1 0 0 1 1 1 0 UAA transporter family Ribophorin_I PF04597.9 ETO12457.1 - 2.2e-18 66.0 1.6 3.6e-18 65.2 1.1 1.4 1 0 0 1 1 1 1 Ribophorin I DUF3519 PF12033.3 ETO12457.1 - 0.72 10.0 4.9 4.4 7.5 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3519) RRM_6 PF14259.1 ETO12458.1 - 0.022 14.7 0.0 0.39 10.7 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO12458.1 - 0.13 12.0 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3552 PF12072.3 ETO12459.1 - 1 8.5 6.4 1.2 8.3 4.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Tenui_NS4 PF03300.8 ETO12460.1 - 0.098 11.7 0.5 0.12 11.4 0.4 1.1 1 0 0 1 1 1 0 Tenuivirus non-structural protein NS4 BUD22 PF09073.5 ETO12460.1 - 0.12 11.3 6.0 0.13 11.3 4.1 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 ETO12461.1 - 0.22 9.3 12.2 0.25 9.2 8.4 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 ETO12461.1 - 1.1 8.3 12.2 1.7 7.6 8.5 1.3 1 0 0 1 1 1 0 BUD22 Nucleoplasmin PF03066.10 ETO12461.1 - 5.7 6.4 11.9 2 7.9 5.4 2.1 2 0 0 2 2 2 0 Nucleoplasmin SDA1 PF05285.7 ETO12461.1 - 6.2 5.9 15.3 9.5 5.3 10.6 1.2 1 0 0 1 1 1 0 SDA1 FAM176 PF14851.1 ETO12461.1 - 9.4 5.8 10.5 2.2 7.9 4.7 1.9 1 1 1 2 2 2 0 FAM176 family WD40 PF00400.27 ETO12462.1 - 4.9e-47 156.2 9.6 6.9e-15 54.2 0.2 6.0 5 1 1 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO12462.1 - 3.4e-07 28.7 0.1 0.063 11.4 0.0 3.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO12462.1 - 1.2e-06 28.3 0.0 0.00084 19.1 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 ETO12462.1 - 3.9e-05 23.2 0.3 0.00017 21.1 0.2 1.8 1 1 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO12462.1 - 8.4e-05 21.0 0.0 0.019 13.2 0.0 2.1 1 1 1 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.7 ETO12462.1 - 0.00054 19.5 1.1 8.2 6.2 0.0 3.4 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 ETO12462.1 - 0.0052 15.8 0.1 8.4 5.3 0.0 3.1 1 1 1 3 3 3 1 Protein of unknown function (DUF1258) Proteasome_A_N PF10584.4 ETO12462.1 - 0.0071 15.6 4.1 7.6 5.9 0.1 4.3 5 0 0 5 5 5 1 Proteasome subunit A N-terminal signature BLUF PF04940.7 ETO12462.1 - 0.0076 15.9 0.0 28 4.5 0.0 4.5 4 1 1 5 5 5 0 Sensors of blue-light using FAD WXG100 PF06013.7 ETO12462.1 - 0.011 15.7 0.0 17 5.4 0.0 4.0 4 1 1 5 5 5 0 Proteins of 100 residues with WXG Gmad1 PF10647.4 ETO12462.1 - 0.024 14.0 0.0 0.37 10.1 0.0 2.3 1 1 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain Nucleoporin_N PF08801.6 ETO12462.1 - 0.032 12.9 1.8 2 7.0 0.0 2.5 1 1 0 2 2 2 0 Nup133 N terminal like Nbas_N PF15492.1 ETO12462.1 - 0.033 13.2 0.4 0.39 9.7 0.0 2.3 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PQQ_3 PF13570.1 ETO12462.1 - 0.067 13.4 0.0 1.9 8.8 0.0 2.6 3 0 0 3 3 3 0 PQQ-like domain NYD-SP28_assoc PF14775.1 ETO12462.1 - 0.071 12.8 0.5 70 3.2 0.0 3.6 4 0 0 4 4 4 0 Sperm tail C-terminal domain YqaJ PF09588.5 ETO12463.1 - 1.1e-05 25.3 0.0 1.8e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain NAD_binding_9 PF13454.1 ETO12465.1 - 0.15 11.8 0.1 0.25 11.1 0.1 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pox_VLTF3 PF04947.9 ETO12467.1 - 0.00068 19.1 1.3 0.001 18.6 0.6 1.5 1 1 0 1 1 1 1 Poxvirus Late Transcription Factor VLTF3 like PI3_PI4_kinase PF00454.22 ETO12469.1 - 2.3e-42 145.0 0.8 8.5e-41 139.9 0.1 2.9 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 ETO12469.1 - 1.6e-32 112.1 5.2 2e-32 111.8 1.8 2.4 2 1 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Mucin PF01456.12 ETO12469.1 - 0.042 13.6 46.1 0.16 11.7 25.8 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein EphA2_TM PF14575.1 ETO12469.1 - 0.066 13.6 0.1 0.28 11.6 0.1 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 ETO12469.1 - 5.7 7.0 7.9 1.1 9.3 0.1 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator AJAP1_PANP_C PF15298.1 ETO12469.1 - 5.7 6.7 30.6 0.066 13.0 2.5 2.4 2 0 0 2 2 2 0 AJAP1/PANP C-terminus AA_permease_2 PF13520.1 ETO12469.1 - 8 4.8 10.8 0.029 12.9 1.0 1.5 2 0 0 2 2 2 0 Amino acid permease Zip PF02535.17 ETO12470.1 - 3.3 6.6 3.8 6.2 5.7 2.6 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter WD40 PF00400.27 ETO12471.1 - 1.3e-66 218.2 24.6 6.6e-13 47.9 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO12471.1 - 4.8e-15 54.7 6.5 2.6e-05 22.5 0.3 5.0 1 1 1 4 4 4 4 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO12471.1 - 1.2e-05 25.6 1.1 1.2e-05 25.6 0.8 2.2 2 0 0 2 2 2 1 TRAF-type zinc finger BBS2_Mid PF14783.1 ETO12471.1 - 0.0034 17.1 0.6 4.9 6.9 0.0 4.5 2 2 3 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Spc7 PF08317.6 ETO12471.1 - 0.086 11.4 40.1 0.058 12.0 10.3 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein HlyD PF00529.15 ETO12471.1 - 7.1 5.8 16.7 14 4.8 11.6 1.4 1 0 0 1 1 1 0 HlyD family secretion protein Crisp PF08562.5 ETO12472.1 - 0.095 12.9 0.5 0.17 12.1 0.4 1.4 1 0 0 1 1 1 0 Crisp RTTN_N PF14726.1 ETO12474.1 - 0.0049 17.4 0.6 0.019 15.5 0.1 2.2 2 0 0 2 2 2 1 Rotatin, an armadillo repeat protein, centriole functioning HEAT PF02985.17 ETO12474.1 - 0.0054 16.7 2.4 2.4 8.4 0.0 4.3 4 0 0 4 4 4 1 HEAT repeat Sigma70_ner PF04546.8 ETO12474.1 - 0.012 15.2 10.7 0.028 14.0 0.2 2.7 3 0 0 3 3 3 0 Sigma-70, non-essential region GlutR_dimer PF00745.15 ETO12474.1 - 0.023 14.6 0.2 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain CDC45 PF02724.9 ETO12475.1 - 0.059 11.4 22.0 0.089 10.8 15.2 1.3 1 0 0 1 1 1 0 CDC45-like protein CENP-T PF15511.1 ETO12475.1 - 0.071 12.3 21.0 0.09 12.0 14.6 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TRAP_alpha PF03896.11 ETO12475.1 - 1.6 7.6 18.6 3.5 6.5 12.9 1.7 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Merozoite_SPAM PF07133.6 ETO12475.1 - 9.2 6.1 48.0 0.13 12.1 27.7 1.9 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) ADIP PF11559.3 ETO12476.1 - 0.011 15.5 15.6 0.022 14.6 10.8 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Striatin PF08232.7 ETO12476.1 - 0.011 15.9 11.8 0.016 15.4 8.1 1.2 1 0 0 1 1 1 0 Striatin family Hema_stalk PF08720.5 ETO12476.1 - 0.022 14.2 2.1 0.032 13.7 1.4 1.3 1 1 0 1 1 1 0 Influenza C hemagglutinin stalk DnaG_DnaB_bind PF08278.6 ETO12476.1 - 0.5 10.5 8.2 0.83 9.8 5.7 1.5 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding GCD14 PF08704.5 ETO12476.1 - 0.91 8.9 8.4 1.3 8.4 5.8 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit ATG16 PF08614.6 ETO12476.1 - 1.5 8.5 18.1 0.061 13.1 6.1 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) V_ATPase_I PF01496.14 ETO12476.1 - 2.1 6.0 11.1 2.5 5.8 7.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Dala_Dala_lig_N PF01820.16 ETO12476.1 - 2.3 8.5 5.5 15 5.9 3.8 2.0 1 1 0 1 1 1 0 D-ala D-ala ligase N-terminus PEHE PF15275.1 ETO12476.1 - 2.8 8.4 7.2 5.5 7.4 5.0 1.6 1 1 0 1 1 1 0 PEHE domain DUF4047 PF13256.1 ETO12476.1 - 6 6.8 14.8 9.8 6.1 10.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) TBPIP PF07106.8 ETO12476.1 - 9.4 5.7 21.2 28 4.1 14.5 1.9 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) F-box PF00646.28 ETO12477.1 - 0.00026 20.5 0.0 0.00055 19.5 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 ETO12477.1 - 0.085 12.5 0.1 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 F-box-like Tho2 PF11262.3 ETO12477.1 - 0.12 11.3 10.0 0.13 11.2 3.4 2.4 2 1 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 IFT20 PF14931.1 ETO12477.1 - 0.44 10.4 9.5 0.73 9.7 2.4 2.7 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 Spc24 PF08286.6 ETO12477.1 - 0.48 10.1 12.1 1.5 8.5 0.5 3.0 2 1 0 3 3 3 0 Spc24 subunit of Ndc80 DUF1640 PF07798.6 ETO12477.1 - 1.8 8.6 10.0 0.45 10.5 4.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) AMPKBI PF04739.10 ETO12478.1 - 0.11 12.3 0.8 0.15 11.9 0.6 1.2 1 0 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interation domain Hydrolase_3 PF08282.7 ETO12478.1 - 0.16 11.5 2.3 0.19 11.2 1.6 1.0 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase ArsB PF02040.10 ETO12479.1 - 1.1e-11 44.4 4.8 1.4e-11 44.0 3.3 1.0 1 0 0 1 1 1 1 Arsenical pump membrane protein CIDE-N PF02017.10 ETO12479.1 - 0.077 12.7 0.1 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 CIDE-N domain MecA PF05389.7 ETO12480.1 - 0.27 10.7 7.8 0.32 10.4 5.4 1.0 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) BSMAP PF12280.3 ETO12480.1 - 1.6 8.5 7.7 1.8 8.4 5.3 1.0 1 0 0 1 1 1 0 Brain specific membrane anchored protein OmpH PF03938.9 ETO12480.1 - 4 7.3 12.2 2.9 7.8 7.6 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Lipase PF00151.14 ETO12480.1 - 4.2 6.4 6.7 4.7 6.3 4.7 1.0 1 0 0 1 1 1 0 Lipase Exonuc_VII_L PF02601.10 ETO12480.1 - 5.4 6.1 10.9 5.7 6.0 7.5 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit YqfQ PF14181.1 ETO12480.1 - 6.3 6.8 16.0 6.8 6.7 11.1 1.0 1 0 0 1 1 1 0 YqfQ-like protein Dynamin_N PF00350.18 ETO12480.1 - 7.9 6.2 6.7 8.1 6.2 4.6 1.1 1 0 0 1 1 1 0 Dynamin family DUF694 PF05107.7 ETO12480.1 - 8.8 5.4 12.5 10 5.2 8.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF694) 4HB_MCP_1 PF12729.2 ETO12480.1 - 8.9 5.6 14.6 10 5.4 10.1 1.0 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction MCM PF00493.18 ETO12481.1 - 2.8e-69 233.4 1.8 2.8e-69 233.4 1.2 1.7 2 0 0 2 2 2 1 MCM2/3/5 family Mg_chelatase PF01078.16 ETO12481.1 - 0.016 14.3 0.7 0.033 13.3 0.1 1.9 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI HrpB7 PF09486.5 ETO12482.1 - 0.0007 19.5 2.1 0.0007 19.5 1.5 2.5 3 0 0 3 3 3 1 Bacterial type III secretion protein (HrpB7) PEP-utilisers_N PF05524.8 ETO12482.1 - 0.012 15.3 2.0 0.012 15.3 1.4 3.5 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal HalX PF08663.5 ETO12482.1 - 0.021 14.7 8.1 0.021 14.7 5.6 4.1 4 1 0 4 4 4 0 HalX domain DUF307 PF03733.8 ETO12483.1 - 0.00024 21.4 11.2 0.00024 21.4 7.8 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF307) DUF4458 PF14660.1 ETO12484.1 - 0.038 13.9 1.3 2.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4458) 7TM_GPCR_Sru PF10322.4 ETO12484.1 - 0.053 12.6 2.2 4.1 6.4 0.2 2.2 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sru Gly-zipper_YMGG PF13441.1 ETO12485.1 - 0.00095 18.6 0.1 0.0029 17.0 0.1 1.7 1 1 0 1 1 1 1 YMGG-like Gly-zipper DivIVA PF05103.8 ETO12485.1 - 0.0048 16.9 8.5 0.0048 16.9 5.9 2.7 2 0 0 2 2 2 1 DivIVA protein MiaE PF06175.6 ETO12485.1 - 0.014 14.8 0.1 0.014 14.8 0.0 2.5 3 0 0 3 3 3 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) DUF3186 PF11382.3 ETO12485.1 - 0.024 13.7 0.3 0.061 12.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) Fe-ADH PF00465.14 ETO12485.1 - 0.06 11.9 0.0 0.095 11.3 0.0 1.5 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase Gly-zipper_Omp PF13488.1 ETO12485.1 - 0.15 11.6 5.1 5 6.8 1.4 2.3 2 0 0 2 2 2 0 Glycine zipper Bacteriocin_IIc PF10439.4 ETO12485.1 - 0.21 11.7 2.5 8.3 6.6 0.1 2.5 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide FlaC_arch PF05377.6 ETO12485.1 - 0.26 11.2 9.6 1.1 9.2 0.9 3.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF948 PF06103.6 ETO12485.1 - 3.4 7.5 15.6 8 6.4 1.8 3.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.7 ETO12485.1 - 4.8 7.5 15.7 22 5.3 7.8 3.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Slu7 PF11708.3 ETO12486.1 - 7.1e-14 52.1 32.0 2.8e-13 50.2 15.6 3.2 3 1 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor CDC45 PF02724.9 ETO12486.1 - 0.017 13.1 15.1 0.028 12.4 10.5 1.3 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.7 ETO12486.1 - 0.14 11.8 26.5 0.012 15.2 14.0 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Pox_P4B PF03292.9 ETO12486.1 - 0.6 7.9 6.8 0.81 7.5 4.7 1.2 1 0 0 1 1 1 0 Poxvirus P4B major core protein DUF1168 PF06658.7 ETO12486.1 - 1.1 8.7 25.1 0.35 10.3 11.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) DUF755 PF05501.6 ETO12486.1 - 1.2 9.1 19.7 0.55 10.2 8.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Tom22 PF04281.8 ETO12486.1 - 3.2 7.2 15.0 0.49 9.9 6.8 2.1 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 DUF2076 PF09849.4 ETO12486.1 - 9.8 6.1 14.2 21 5.0 9.8 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) RhoGAP PF00620.22 ETO12487.1 - 7.3e-19 67.8 0.0 2.1e-18 66.3 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain CENP-B_dimeris PF09026.5 ETO12487.1 - 0.038 14.2 0.5 0.038 14.2 0.4 4.2 3 2 1 4 4 4 0 Centromere protein B dimerisation domain Peptidase_C14 PF00656.17 ETO12488.1 - 9e-17 61.5 2.2 2.1e-16 60.3 1.5 1.7 1 1 0 1 1 1 1 Caspase domain DUF3698 PF12479.3 ETO12488.1 - 0.0087 16.1 1.6 0.16 12.0 0.3 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3698) YwhD PF08741.5 ETO12488.1 - 0.29 10.5 5.3 0.18 11.1 0.8 2.5 2 1 1 3 3 3 0 YwhD family TPR_12 PF13424.1 ETO12489.1 - 6.3e-39 131.7 9.1 1e-28 99.0 1.4 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO12489.1 - 9.3e-31 104.1 22.7 7.7e-11 41.1 1.6 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO12489.1 - 6.8e-29 97.3 3.5 9.4e-10 37.5 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO12489.1 - 4.8e-27 93.4 9.3 8e-19 67.0 1.5 3.1 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 ETO12489.1 - 5.9e-26 88.2 18.4 1.7e-08 33.7 0.6 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO12489.1 - 1.9e-25 87.9 0.0 3.7e-09 36.2 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO12489.1 - 3.3e-22 76.5 27.7 8.2e-10 37.7 1.5 3.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO12489.1 - 6.6e-13 48.9 0.2 0.011 16.3 0.1 3.6 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO12489.1 - 1.8e-12 46.3 9.6 0.0013 18.8 0.0 4.4 5 1 0 5 5 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO12489.1 - 1.8e-12 46.8 4.8 0.0041 17.4 0.5 3.5 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO12489.1 - 4.6e-11 42.3 0.0 0.06 14.0 0.0 3.4 4 0 0 4 4 3 3 Tetratricopeptide repeat SNAP PF14938.1 ETO12489.1 - 1.1e-08 34.6 5.7 2.2e-05 23.7 0.6 2.1 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP PPR PF01535.15 ETO12489.1 - 2.8e-08 33.2 4.8 0.0092 15.8 0.0 4.1 4 0 0 4 4 4 2 PPR repeat TPR_3 PF07720.7 ETO12489.1 - 3.1e-08 33.2 16.5 0.042 13.6 2.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 ETO12489.1 - 1.8e-07 31.1 12.0 7.7e-05 22.7 1.9 2.8 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO12489.1 - 5.9e-07 29.7 1.3 0.015 15.6 0.1 3.5 2 2 1 3 3 3 3 Tetratricopeptide repeat Sel1 PF08238.7 ETO12489.1 - 4.1e-06 27.2 10.3 0.38 11.4 0.1 3.8 4 0 0 4 4 3 3 Sel1 repeat SHNi-TPR PF10516.4 ETO12489.1 - 4.4e-05 22.6 0.2 0.69 9.2 0.0 3.4 3 0 0 3 3 3 2 SHNi-TPR MIT PF04212.13 ETO12489.1 - 6.8e-05 22.6 12.1 0.091 12.6 0.3 3.3 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain ATP-synt_E_2 PF08112.6 ETO12489.1 - 0.00025 21.0 5.5 0.26 11.3 0.8 2.8 2 0 0 2 2 2 2 ATP synthase epsilon subunit RPN7 PF10602.4 ETO12489.1 - 0.00036 19.9 7.5 0.18 11.1 0.1 3.1 1 1 2 3 3 3 2 26S proteasome subunit RPN7 Fis1_TPR_C PF14853.1 ETO12489.1 - 0.00053 19.8 14.0 0.007 16.2 1.4 3.4 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat Mob_Pre PF01076.14 ETO12489.1 - 0.00072 19.2 2.0 0.00094 18.8 0.5 1.7 1 1 1 2 2 2 2 Plasmid recombination enzyme DUF2225 PF09986.4 ETO12489.1 - 0.0011 18.4 6.8 0.22 10.9 0.8 2.4 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) DUF627 PF04781.7 ETO12489.1 - 0.0015 18.1 6.2 0.87 9.2 0.2 3.1 1 1 2 3 3 3 2 Protein of unknown function (DUF627) Clathrin PF00637.15 ETO12489.1 - 0.0029 17.1 4.4 4.7 6.7 0.1 3.3 2 1 1 3 3 3 0 Region in Clathrin and VPS PPR_2 PF13041.1 ETO12489.1 - 0.0033 17.3 5.1 4 7.5 0.0 3.9 4 0 0 4 4 4 1 PPR repeat family TPR_9 PF13371.1 ETO12489.1 - 0.007 16.1 0.0 1.4 8.8 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat Pep3_Vps18 PF05131.9 ETO12489.1 - 0.034 13.5 3.7 4.1 6.8 0.0 3.4 3 1 0 4 4 4 0 Pep3/Vps18/deep orange family Mad3_BUB1_I PF08311.7 ETO12489.1 - 0.076 12.8 7.3 1.3 8.8 0.1 3.1 2 1 1 3 3 3 0 Mad3/BUB1 homology region 1 UPF0223 PF05256.7 ETO12489.1 - 0.095 12.8 3.2 1.8 8.7 0.1 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0223) YlbE PF14003.1 ETO12489.1 - 0.1 12.6 0.2 8.3 6.5 0.0 2.8 2 1 1 3 3 2 0 YlbE-like protein DUF357 PF04010.8 ETO12489.1 - 0.11 12.2 9.6 3.8 7.2 1.2 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF357) Ten1_2 PF15490.1 ETO12489.1 - 0.13 11.8 0.1 0.38 10.3 0.0 1.9 2 0 0 2 2 2 0 Telomere-capping, CST complex subunit SPO22 PF08631.5 ETO12489.1 - 0.15 11.0 9.0 4.9 6.1 0.2 3.7 3 1 0 4 4 4 0 Meiosis protein SPO22/ZIP4 like Ubiq-assoc PF09145.5 ETO12489.1 - 2.8 7.8 17.9 4.8 7.1 0.2 4.8 2 2 2 4 4 4 0 Ubiquitin-associated Metallophos PF00149.23 ETO12490.1 - 1.4e-11 44.1 2.9 6.6e-11 41.9 2.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 ETO12490.1 - 1.8e-10 40.7 0.5 1.8e-10 40.7 0.3 2.6 3 0 0 3 3 3 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 ETO12490.1 - 2.5e-05 23.0 0.7 0.00028 19.6 0.1 2.1 2 0 0 2 2 2 1 PhoD-like phosphatase zf-RING_2 PF13639.1 ETO12491.1 - 1e-09 38.0 8.7 3e-09 36.5 6.0 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 ETO12491.1 - 3.7e-07 29.7 11.5 3.7e-07 29.7 8.0 2.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 ETO12491.1 - 1.1e-06 28.2 9.0 1.1e-06 28.2 6.2 3.5 3 1 1 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.20 ETO12491.1 - 1.6e-06 27.6 13.5 3.5e-05 23.3 9.3 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO12491.1 - 1.9e-06 27.7 11.7 2.3e-05 24.3 8.1 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO12491.1 - 2.8e-05 23.7 14.1 0.00017 21.2 9.8 2.2 1 1 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 ETO12491.1 - 0.0004 20.4 5.5 0.0091 16.0 2.0 2.8 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_6 PF14835.1 ETO12491.1 - 0.00094 18.9 1.0 0.0029 17.3 0.7 1.8 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 ETO12491.1 - 0.0033 17.2 7.5 0.0033 17.2 5.2 2.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Scytalone_dh PF02982.9 ETO12491.1 - 0.0057 16.2 0.1 0.01 15.3 0.1 1.4 1 0 0 1 1 1 1 Scytalone dehydratase KID PF02524.9 ETO12491.1 - 0.037 14.0 0.4 49 4.7 0.0 4.2 3 0 0 3 3 3 0 KID repeat zf-Apc11 PF12861.2 ETO12491.1 - 0.043 13.6 9.6 0.87 9.4 1.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger 3HCDH_N PF02737.13 ETO12491.1 - 0.81 9.3 4.6 0.46 10.1 0.2 2.7 2 2 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-RING_4 PF14570.1 ETO12491.1 - 2 8.0 11.7 4.6 6.9 0.2 2.9 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 ETO12491.1 - 9.6 5.8 14.0 2.1 7.9 5.5 2.8 2 1 1 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit Glyco_tran_WbsX PF14307.1 ETO12492.1 - 0.00035 19.8 10.5 0.0013 18.0 6.4 2.4 1 1 0 1 1 1 1 Glycosyltransferase WbsX WD40 PF00400.27 ETO12493.1 - 1.6e-81 265.5 18.5 2.5e-12 46.1 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO12493.1 - 1.5e-06 26.6 6.1 0.0059 14.8 0.0 3.8 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO12493.1 - 0.00014 20.7 8.7 0.027 13.2 4.2 2.9 1 1 1 2 2 2 2 Nup133 N terminal like Nbas_N PF15492.1 ETO12493.1 - 0.0014 17.8 1.2 0.66 9.0 0.0 3.5 2 1 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Str_synth PF03088.11 ETO12493.1 - 0.0031 17.5 0.6 9.1 6.3 0.0 4.3 4 1 1 5 5 5 1 Strictosidine synthase Cytochrom_D1 PF02239.11 ETO12493.1 - 0.0036 15.6 4.1 0.36 9.0 0.1 3.2 4 0 0 4 4 4 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO12493.1 - 0.01 15.3 0.0 0.055 12.9 0.0 2.2 1 1 0 1 1 1 0 PQQ-like domain DPPIV_N PF00930.16 ETO12493.1 - 0.015 13.8 0.0 2.8 6.4 0.0 3.6 2 1 2 5 5 5 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Proteasome_A_N PF10584.4 ETO12493.1 - 0.022 14.0 4.6 24 4.3 0.1 5.5 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature TBP PF00352.16 ETO12493.1 - 0.028 13.7 0.0 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 Transcription factor TFIID (or TATA-binding protein, TBP) PD40 PF07676.7 ETO12493.1 - 0.07 12.8 5.5 5.5 6.7 0.1 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Voltage_CLC PF00654.15 ETO12494.1 - 1.4e-38 132.8 19.5 1.4e-21 76.9 2.0 2.0 1 1 1 2 2 2 2 Voltage gated chloride channel zf-RING_2 PF13639.1 ETO12495.1 - 1.8 8.4 9.4 0.38 10.6 2.5 2.3 2 0 0 2 2 2 0 Ring finger domain G-alpha PF00503.15 ETO12496.1 - 3.2e-102 342.1 10.0 3.8e-102 341.8 6.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO12496.1 - 2.9e-14 52.7 2.2 8.6e-11 41.3 0.3 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 ETO12496.1 - 5e-05 23.7 2.5 0.16 12.4 0.0 3.1 1 1 1 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 ETO12496.1 - 0.0018 17.4 0.8 0.11 11.6 0.1 2.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 ETO12496.1 - 0.0036 17.2 0.1 0.5 10.3 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 ETO12496.1 - 0.029 13.7 0.5 5.9 6.2 0.1 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 ETO12496.1 - 0.034 14.0 0.2 0.21 11.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 ETO12496.1 - 0.072 12.6 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 ETO12497.1 - 1.2e-31 109.6 0.0 2.8e-31 108.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETO12497.1 - 4.8e-05 23.5 0.0 0.00017 21.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO12497.1 - 0.0003 21.5 0.0 0.0017 19.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 ETO12497.1 - 0.0005 19.7 0.1 0.03 14.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) NACHT PF05729.7 ETO12497.1 - 0.0038 16.8 0.0 0.0073 15.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.1 ETO12497.1 - 0.0041 16.9 0.1 0.037 13.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETO12497.1 - 0.0056 16.6 0.2 0.2 11.6 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain Vps4_C PF09336.5 ETO12497.1 - 0.013 15.3 0.0 0.046 13.6 0.0 2.0 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain RNA_helicase PF00910.17 ETO12497.1 - 0.023 14.8 1.6 0.29 11.3 0.0 3.2 3 0 0 3 3 3 0 RNA helicase AAA_18 PF13238.1 ETO12497.1 - 0.028 14.7 0.4 0.29 11.4 0.0 2.7 2 2 0 2 2 2 0 AAA domain RuvB_N PF05496.7 ETO12497.1 - 0.036 13.1 0.0 0.17 10.9 0.0 2.1 3 0 0 3 3 3 0 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 ETO12497.1 - 0.039 13.8 0.0 0.13 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 ETO12497.1 - 0.044 12.9 0.2 0.11 11.6 0.1 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 ETO12497.1 - 0.057 12.8 0.3 2.8 7.2 0.1 2.3 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.21 ETO12497.1 - 0.12 11.8 0.0 0.34 10.3 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Tox-HNH-HHH PF15637.1 ETO12497.1 - 0.21 11.3 2.0 0.47 10.2 1.4 1.6 1 0 0 1 1 1 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif DUF3829 PF12889.2 ETO12498.1 - 0.00031 20.0 1.0 0.00042 19.5 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3829) DivIVA PF05103.8 ETO12498.1 - 0.048 13.7 5.9 0.082 12.9 4.1 1.4 1 0 0 1 1 1 0 DivIVA protein Baculo_PEP_C PF04513.7 ETO12498.1 - 0.048 13.4 2.7 0.077 12.8 1.9 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_GPO PF05929.6 ETO12498.1 - 0.049 12.8 2.9 0.07 12.3 2.0 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase CK2S PF15011.1 ETO12498.1 - 0.071 12.8 1.8 0.16 11.7 0.9 1.8 1 1 0 1 1 1 0 Casein Kinase 2 substrate IncA PF04156.9 ETO12498.1 - 0.59 9.7 6.5 1.1 8.7 4.5 1.4 1 1 0 1 1 1 0 IncA protein NPV_P10 PF05531.7 ETO12498.1 - 0.93 9.7 6.8 34 4.7 4.7 2.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF4355 PF14265.1 ETO12498.1 - 0.94 9.4 7.9 7.2 6.5 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4355) Seryl_tRNA_N PF02403.17 ETO12498.1 - 1.2 9.2 9.0 5 7.1 5.9 2.1 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 ETO12498.1 - 1.6 8.2 5.4 4 6.9 3.6 1.8 1 1 0 1 1 1 0 Septum formation initiator Fib_alpha PF08702.5 ETO12498.1 - 2.2 8.4 7.8 5.8 7.0 5.4 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Snapin_Pallidin PF14712.1 ETO12498.1 - 2.5 8.4 7.9 1.3 9.3 2.6 2.1 1 1 1 2 2 2 0 Snapin/Pallidin FlaC_arch PF05377.6 ETO12498.1 - 3.5 7.5 7.6 27 4.7 1.5 2.8 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) PMP22_Claudin PF00822.15 ETO12499.1 - 0.02 14.5 0.6 0.022 14.4 0.4 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family SPX PF03105.14 ETO12500.1 - 7.8e-05 22.5 11.6 7.8e-05 22.5 8.0 3.4 1 1 1 2 2 2 1 SPX domain DUF3172 PF11371.3 ETO12500.1 - 0.061 12.8 0.2 0.15 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3172) CRIC_ras_sig PF10534.4 ETO12500.1 - 0.078 13.0 3.7 0.25 11.4 0.1 3.3 3 0 0 3 3 3 0 Connector enhancer of kinase suppressor of ras ARL2_Bind_BART PF11527.3 ETO12501.1 - 0.13 12.0 3.3 1.1 9.1 2.3 2.0 1 1 0 1 1 1 0 The ARF-like 2 binding protein BART UQ_con PF00179.21 ETO12503.1 - 6.1e-28 97.0 0.0 6.1e-28 97.0 0.0 2.2 2 0 0 2 2 1 1 Ubiquitin-conjugating enzyme U-box PF04564.10 ETO12503.1 - 1.2e-11 44.3 0.1 1.4e-09 37.7 0.0 2.7 2 0 0 2 2 2 1 U-box domain MIP-T3 PF10243.4 ETO12503.1 - 0.00039 19.0 37.3 0.00084 17.9 25.9 1.4 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 zf-Nse PF11789.3 ETO12503.1 - 0.00052 19.4 0.1 0.55 9.7 0.1 3.5 3 0 0 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit Mem_trans PF03547.13 ETO12503.1 - 0.081 11.2 2.6 0.15 10.3 1.8 1.5 1 0 0 1 1 1 0 Membrane transport protein Suf PF05843.9 ETO12503.1 - 0.12 12.0 22.3 0.45 10.1 15.3 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Rtf2 PF04641.7 ETO12503.1 - 0.79 8.8 0.0 0.79 8.8 0.0 3.6 2 1 1 3 3 2 0 Rtf2 RING-finger LMBR1 PF04791.11 ETO12503.1 - 0.8 8.2 5.4 1.5 7.2 3.8 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein Zip PF02535.17 ETO12503.1 - 0.84 8.5 7.3 1.5 7.7 5.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2201_N PF13203.1 ETO12503.1 - 0.96 8.5 25.0 2.1 7.4 17.3 1.5 1 0 0 1 1 1 0 Putative metallopeptidase domain Otopetrin PF03189.8 ETO12503.1 - 6.4 5.6 5.5 12 4.7 3.8 1.4 1 0 0 1 1 1 0 Otopetrin RhoGEF PF00621.15 ETO12504.1 - 5.2e-14 52.5 0.4 6.8e-14 52.1 0.3 1.1 1 0 0 1 1 1 1 RhoGEF domain Pkinase PF00069.20 ETO12506.1 - 1.7e-58 197.8 1.2 4.7e-46 157.0 0.9 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO12506.1 - 7.1e-28 97.3 0.9 2.4e-16 59.6 0.2 3.2 2 1 1 3 3 3 3 Protein tyrosine kinase Kdo PF06293.9 ETO12506.1 - 0.00054 19.0 0.3 0.0011 18.1 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETO12506.1 - 0.0033 16.4 0.0 0.0077 15.2 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Pex26 PF07163.7 ETO12506.1 - 0.066 12.1 0.6 0.11 11.3 0.1 1.6 2 0 0 2 2 2 0 Pex26 protein Ank_2 PF12796.2 ETO12507.1 - 1.2e-09 38.3 0.0 4.4e-09 36.5 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) HEAT_2 PF13646.1 ETO12507.1 - 6.6e-09 35.9 0.0 7.5e-05 22.9 0.0 2.3 1 1 1 2 2 2 2 HEAT repeats Ank_3 PF13606.1 ETO12507.1 - 6.7e-09 35.1 0.1 0.00063 19.7 0.0 3.4 2 0 0 2 2 2 2 Ankyrin repeat HEAT PF02985.17 ETO12507.1 - 5.5e-08 32.2 0.1 0.018 15.0 0.0 3.7 4 0 0 4 4 4 2 HEAT repeat Ank PF00023.25 ETO12507.1 - 1.7e-07 30.7 0.1 2.3e-05 23.9 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 ETO12507.1 - 2e-07 31.3 0.2 6.9e-07 29.6 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO12507.1 - 5.6e-06 26.4 0.2 3.5e-05 23.9 0.1 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) HEAT_EZ PF13513.1 ETO12507.1 - 0.0012 19.2 0.0 1.5 9.4 0.0 3.3 3 0 0 3 3 3 1 HEAT-like repeat DUF2435 PF10363.4 ETO12507.1 - 0.11 12.4 1.8 5.2 7.0 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2435) HEAT PF02985.17 ETO12508.1 - 3.5e-05 23.5 0.1 0.66 10.2 0.0 4.6 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 ETO12508.1 - 0.0001 22.5 0.0 0.027 14.7 0.0 3.2 2 1 0 3 3 3 1 HEAT repeats CLASP_N PF12348.3 ETO12508.1 - 0.0016 17.8 2.5 0.0022 17.3 0.1 2.4 3 0 0 3 3 3 1 CLASP N terminal TIP120 PF08623.5 ETO12508.1 - 0.0078 15.8 3.0 0.026 14.1 0.0 2.9 2 1 1 3 3 3 1 TATA-binding protein interacting (TIP20) THDPS_N PF14790.1 ETO12508.1 - 0.094 12.3 5.4 0.064 12.8 2.0 2.1 2 1 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal SelP_N PF04592.9 ETO12509.1 - 0.017 14.5 6.9 0.024 14.0 4.8 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF853 PF05872.7 ETO12509.1 - 0.61 8.3 3.4 0.56 8.4 2.4 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Z1 PF10593.4 ETO12509.1 - 5.8 6.0 10.3 6.6 5.8 7.2 1.1 1 0 0 1 1 1 0 Z1 domain Spo0A_C PF08769.6 ETO12510.1 - 3.6 7.5 6.2 6.8 6.6 4.0 2.0 1 1 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal CLTH PF10607.4 ETO12511.1 - 5.5e-09 35.8 3.5 5.5e-09 35.8 2.4 1.9 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain UME PF08064.8 ETO12511.1 - 0.04 13.8 1.4 2.3 8.1 0.1 2.5 2 0 0 2 2 2 0 UME (NUC010) domain zf-C2H2_jaz PF12171.3 ETO12512.1 - 0.0022 18.0 0.7 0.0022 18.0 0.5 4.7 4 1 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 ETO12512.1 - 0.004 17.3 13.5 1.2 9.4 1.2 4.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type RRM_1 PF00076.17 ETO12512.1 - 0.023 14.3 0.1 0.054 13.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Macoilin PF09726.4 ETO12512.1 - 0.06 11.6 18.5 0.088 11.0 12.8 1.3 1 0 0 1 1 1 0 Transmembrane protein Preseq_ALAS PF09029.5 ETO12512.1 - 0.1 12.6 0.0 0.1 12.6 0.0 2.2 2 1 1 3 3 3 0 5-aminolevulinate synthase presequence Ndc1_Nup PF09531.5 ETO12512.1 - 0.19 10.1 4.2 0.34 9.2 2.9 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1632 PF07857.7 ETO12512.1 - 4.7 6.3 5.2 2.2 7.4 1.0 2.0 1 1 1 2 2 2 0 CEO family (DUF1632) WD40 PF00400.27 ETO12513.1 - 1.7e-21 75.2 10.2 1.5e-10 40.5 0.7 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO12513.1 - 3.6e-05 22.1 0.8 0.0072 14.5 0.1 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 YHYH PF14240.1 ETO12513.1 - 0.052 13.2 0.9 0.067 12.8 0.3 1.5 1 1 1 2 2 2 0 YHYH protein PUB PF09409.5 ETO12514.1 - 6.2e-05 22.6 0.5 0.00036 20.2 0.1 2.4 2 0 0 2 2 2 1 PUB domain WD40 PF00400.27 ETO12517.1 - 1.2e-12 47.1 6.0 5.2e-10 38.8 0.0 4.0 4 0 0 4 4 4 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO12517.1 - 0.00036 18.8 0.1 0.00048 18.3 0.0 1.4 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO12517.1 - 0.0021 16.8 1.0 0.019 13.7 0.1 2.3 1 1 1 2 2 2 1 Nup133 N terminal like eIF2A PF08662.6 ETO12517.1 - 0.053 13.2 0.0 0.43 10.2 0.0 2.0 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A SURF6 PF04935.7 ETO12518.1 - 7.8e-06 25.3 47.2 0.00011 21.6 32.7 2.3 1 1 0 1 1 1 1 Surfeit locus protein 6 Snapin_Pallidin PF14712.1 ETO12518.1 - 2.9 8.2 9.6 1.9 8.8 2.1 2.9 1 1 1 2 2 2 0 Snapin/Pallidin AAA_34 PF13872.1 ETO12519.1 - 0.088 11.5 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 Kelch_2 PF07646.10 ETO12519.1 - 0.1 12.4 0.1 0.41 10.5 0.0 2.0 1 1 0 1 1 1 0 Kelch motif LVIVD PF08309.6 ETO12519.1 - 1.1 8.3 4.7 1.6 7.8 2.4 2.0 2 1 0 2 2 2 0 LVIVD repeat PDZ PF00595.19 ETO12521.1 - 9.3e-07 28.9 0.0 2.3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) FYVE PF01363.16 ETO12521.1 - 9.5e-07 28.6 13.6 2.1e-06 27.4 9.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger zf-HIT PF04438.11 ETO12521.1 - 0.0081 15.7 4.6 0.0081 15.7 3.2 1.6 2 0 0 2 2 2 1 HIT zinc finger AAA PF00004.24 ETO12522.1 - 1.9e-37 128.3 0.1 3.7e-37 127.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETO12522.1 - 2e-05 24.7 0.1 0.0015 18.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 ETO12522.1 - 4.7e-05 23.3 0.0 8.7e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 ETO12522.1 - 5.9e-05 22.2 0.0 0.00011 21.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 ETO12522.1 - 7.3e-05 22.5 0.0 0.00058 19.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Vps4_C PF09336.5 ETO12522.1 - 0.00035 20.3 0.1 0.0014 18.5 0.0 2.0 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain TIP49 PF06068.8 ETO12522.1 - 0.00066 18.5 0.0 0.0011 17.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 ETO12522.1 - 0.0018 18.3 0.0 0.0036 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 ETO12522.1 - 0.0027 17.2 0.4 2.9 7.2 0.0 3.2 2 1 1 3 3 3 2 AAA-like domain Mg_chelatase PF01078.16 ETO12522.1 - 0.004 16.3 0.0 0.0094 15.1 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ASD1 PF08688.5 ETO12522.1 - 0.013 15.3 1.2 0.027 14.2 0.8 1.5 1 0 0 1 1 1 0 Apx/Shroom domain ASD1 AAA_17 PF13207.1 ETO12522.1 - 0.023 15.4 0.3 0.11 13.3 0.0 2.4 2 1 0 2 2 1 0 AAA domain EppA_BapA PF07268.6 ETO12522.1 - 0.026 14.2 0.1 0.075 12.7 0.0 1.7 1 0 0 1 1 1 0 Exported protein precursor (EppA/BapA) AAA_14 PF13173.1 ETO12522.1 - 0.042 13.7 0.0 0.099 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 ETO12522.1 - 0.046 13.3 0.1 0.11 12.1 0.1 1.6 1 1 0 1 1 1 0 Bacterial dnaA protein MIT PF04212.13 ETO12522.1 - 0.07 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain AAA_19 PF13245.1 ETO12522.1 - 0.079 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 ETO12522.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 ETO12522.1 - 0.13 11.6 0.1 1.8 7.9 0.0 2.1 1 1 0 2 2 2 0 AAA domain Histone PF00125.19 ETO12523.1 - 1.2e-12 47.7 0.1 2.5e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 ETO12523.1 - 0.0012 18.8 0.1 0.0036 17.3 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 ETO12523.1 - 0.003 17.4 0.0 0.0059 16.5 0.0 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 ETO12523.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Kinetochore component CENP-S Thioredoxin_6 PF13848.1 ETO12524.1 - 2.2e-22 79.7 3.5 3.9e-19 69.1 0.1 2.5 3 0 0 3 3 3 2 Thioredoxin-like domain DUF2606 PF10794.4 ETO12524.1 - 0.034 13.5 0.3 0.067 12.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) Thioredoxin PF00085.15 ETO12524.1 - 0.042 13.5 0.1 5.7 6.6 0.0 2.6 1 1 1 2 2 2 0 Thioredoxin Atrophin-1 PF03154.10 ETO12525.1 - 0.95 7.5 3.5 1.3 7.0 2.4 1.1 1 0 0 1 1 1 0 Atrophin-1 family RVT_1 PF00078.22 ETO12526.1 - 9.7e-38 129.6 0.3 3.1e-37 128.0 0.2 2.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 ETO12526.1 - 5.2e-21 74.4 1.5 1.3e-20 73.1 0.4 2.3 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 ETO12526.1 - 2.4e-18 66.7 0.8 1e-17 64.7 0.0 2.6 2 0 0 2 2 2 1 RNase H zf-RVT PF13966.1 ETO12526.1 - 0.00021 21.5 0.1 0.00021 21.5 0.1 3.8 4 0 0 4 4 4 1 zinc-binding in reverse transcriptase Pro_3_hydrox_C PF05373.6 ETO12528.1 - 0.11 12.6 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal Troponin PF00992.15 ETO12528.1 - 0.87 9.6 4.4 0.24 11.4 0.7 1.7 2 0 0 2 2 2 0 Troponin Kelch_6 PF13964.1 ETO12529.1 - 2.6e-05 24.2 4.5 0.44 10.8 0.2 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO12529.1 - 2.9e-05 23.9 6.3 0.44 10.5 0.4 4.0 4 1 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 ETO12529.1 - 0.00041 20.0 0.9 1 9.2 0.0 4.0 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 ETO12529.1 - 0.0042 16.5 9.5 0.17 11.4 0.0 4.0 4 2 0 4 4 4 2 Kelch motif DUF3926 PF13080.1 ETO12529.1 - 0.0056 16.1 0.2 0.011 15.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3926) Kelch_3 PF13415.1 ETO12529.1 - 0.11 12.7 0.5 26 5.1 0.0 3.6 5 0 0 5 5 5 0 Galactose oxidase, central domain WD40 PF00400.27 ETO12530.1 - 1.1e-57 189.9 32.3 4e-12 45.5 0.0 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO12530.1 - 8.1e-12 44.0 11.8 0.0037 15.4 0.3 5.9 2 2 3 5 5 5 5 Nucleoporin Nup120/160 Ig_2 PF13895.1 ETO12530.1 - 0.076 13.1 0.3 0.19 11.8 0.2 1.7 1 0 0 1 1 1 0 Immunoglobulin domain DUF851 PF05867.6 ETO12530.1 - 0.13 11.5 0.0 0.38 9.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF851) NPR3 PF03666.8 ETO12532.1 - 0.026 13.0 5.1 0.032 12.7 3.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Dala_Dala_lig_N PF01820.16 ETO12532.1 - 0.053 13.8 0.7 0.068 13.4 0.5 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Tetraspannin PF00335.15 ETO12532.1 - 0.079 12.2 0.1 0.079 12.2 0.1 1.9 2 0 0 2 2 2 0 Tetraspanin family Ni_hydr_CYTB PF01292.15 ETO12532.1 - 0.11 11.8 0.1 0.21 10.9 0.1 1.6 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 DUF262 PF03235.9 ETO12532.1 - 0.21 11.5 4.2 0.24 11.3 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 DUF4337 PF14235.1 ETO12533.1 - 0.58 9.9 3.7 0.88 9.3 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Imm36 PF15597.1 ETO12533.1 - 1.8 8.7 5.7 1 9.5 0.8 2.7 2 1 1 3 3 3 0 Immunity protein 36 Acetyltransf_1 PF00583.19 ETO12535.1 - 2.8e-10 40.1 0.0 4.9e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETO12535.1 - 3.8e-07 30.1 0.0 1.4e-06 28.3 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETO12535.1 - 0.00027 20.6 0.0 0.00066 19.3 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 ETO12535.1 - 0.0018 18.1 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 ETO12535.1 - 0.002 18.3 0.1 0.0047 17.0 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 ETO12535.1 - 0.015 15.1 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 ETO12535.1 - 0.029 14.4 0.0 0.057 13.5 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETO12535.1 - 0.057 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 ETO12535.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-RING_2 PF13639.1 ETO12536.1 - 9.6e-05 22.1 0.9 9.6e-05 22.1 0.6 2.2 2 0 0 2 2 2 1 Ring finger domain SOG2 PF10428.4 ETO12537.1 - 0.0025 16.5 0.8 0.0026 16.4 0.5 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein DUF364 PF04016.7 ETO12537.1 - 0.092 12.0 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF364) Eapp_C PF10238.4 ETO12537.1 - 0.18 11.6 10.9 0.37 10.6 7.6 1.5 1 0 0 1 1 1 0 E2F-associated phosphoprotein Pex14_N PF04695.8 ETO12537.1 - 0.24 11.4 5.6 0.068 13.2 1.0 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FimP PF09766.4 ETO12537.1 - 0.91 8.5 8.4 1.6 7.7 3.7 2.0 2 0 0 2 2 2 0 Fms-interacting protein DUF1980 PF09323.5 ETO12537.1 - 3.8 7.2 11.7 0.022 14.4 1.5 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) Nuc_sug_transp PF04142.10 ETO12538.1 - 1.7e-09 37.1 23.7 3.8e-09 36.0 16.4 1.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 ETO12538.1 - 1.8e-06 28.0 26.9 3.9e-05 23.6 5.8 2.5 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 ETO12538.1 - 0.0014 17.6 30.4 0.026 13.4 21.1 2.1 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.1 ETO12538.1 - 0.56 10.4 23.2 0.11 12.6 2.2 2.6 2 1 0 2 2 2 0 Multidrug resistance efflux transporter DUF1168 PF06658.7 ETO12538.1 - 4.3 6.8 30.7 2 7.9 19.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1168) DUF2796 PF10986.3 ETO12538.1 - 6.1 6.7 12.8 9.9 6.1 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) HOOK PF05622.7 ETO12539.1 - 4.7e-07 28.0 89.9 5e-06 24.6 0.5 5.9 2 2 3 5 5 5 2 HOOK protein CAMSAP_CH PF11971.3 ETO12539.1 - 4.7e-06 26.1 0.9 0.00072 19.1 0.1 3.1 2 0 0 2 2 2 1 CAMSAP CH domain Laminin_I PF06008.9 ETO12539.1 - 0.0008 18.8 18.8 0.0008 18.8 13.0 4.6 2 2 2 4 4 4 1 Laminin Domain I Phage_GP20 PF06810.6 ETO12539.1 - 0.0026 17.2 12.1 0.0026 17.2 8.4 6.8 2 1 3 6 6 6 1 Phage minor structural protein GP20 CH PF00307.26 ETO12539.1 - 0.005 16.8 0.0 0.005 16.8 0.0 3.5 3 0 0 3 3 3 1 Calponin homology (CH) domain IncA PF04156.9 ETO12539.1 - 0.23 11.0 83.3 0.011 15.4 13.0 5.1 1 1 2 4 4 4 0 IncA protein Reo_sigmaC PF04582.7 ETO12539.1 - 0.36 9.9 14.4 8.8 5.3 0.8 4.3 3 1 0 4 4 4 0 Reovirus sigma C capsid protein DUF3584 PF12128.3 ETO12539.1 - 0.96 6.6 69.5 0.76 7.0 29.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) CH PF00307.26 ETO12540.1 - 3.1e-63 210.5 0.3 2.8e-19 69.1 0.0 5.1 4 1 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 ETO12540.1 - 1.3e-09 37.6 0.0 0.034 13.7 0.0 3.6 3 0 0 3 3 3 3 CAMSAP CH domain Rhamnogal_lyase PF06045.6 ETO12541.1 - 0.022 14.0 0.5 0.053 12.7 0.1 1.7 1 1 1 2 2 2 0 Rhamnogalacturonate lyase family DUF1510 PF07423.6 ETO12542.1 - 0.011 15.0 1.9 0.013 14.8 1.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2982 PF11201.3 ETO12542.1 - 0.079 12.3 0.5 0.083 12.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2982) DUF989 PF06181.6 ETO12542.1 - 0.11 11.5 0.1 0.12 11.3 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF989) BLVR PF06375.6 ETO12542.1 - 0.16 11.8 6.7 0.16 11.7 4.6 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) DivIC PF04977.10 ETO12542.1 - 0.26 10.7 4.0 0.086 12.3 0.7 1.7 2 0 0 2 2 2 0 Septum formation initiator Peptidase_S49_N PF08496.5 ETO12542.1 - 0.48 10.2 7.5 0.53 10.0 5.2 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TPR_11 PF13414.1 ETO12543.1 - 1.5e-06 27.7 1.1 6.7e-05 22.4 0.1 3.0 1 1 0 2 2 2 1 TPR repeat TPR_19 PF14559.1 ETO12543.1 - 7.9e-05 22.9 0.0 0.0012 19.0 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO12543.1 - 8e-05 22.6 12.0 0.0056 16.7 0.1 3.9 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 ETO12543.1 - 0.0013 19.1 0.0 0.031 14.8 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO12543.1 - 0.0078 16.0 0.1 0.24 11.3 0.0 3.2 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.12 ETO12543.1 - 0.011 15.6 5.7 0.16 11.9 0.1 4.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETO12543.1 - 0.024 14.3 6.0 4.7 7.2 0.0 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat Acetyltransf_3 PF13302.1 ETO12543.1 - 0.045 13.9 0.1 0.088 12.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TPR_16 PF13432.1 ETO12543.1 - 0.078 13.6 0.0 1.3 9.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat MCR_D PF02505.9 ETO12543.1 - 0.1 12.1 0.2 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Methyl-coenzyme M reductase operon protein D TPR_1 PF00515.23 ETO12543.1 - 1.4 8.6 7.9 1 9.0 0.1 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Nucleoplasmin PF03066.10 ETO12544.1 - 0.097 12.1 21.7 0.018 14.5 6.6 2.4 2 0 0 2 2 2 0 Nucleoplasmin Zip PF02535.17 ETO12544.1 - 0.62 9.0 6.0 1 8.2 0.3 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter DUF1675 PF07897.6 ETO12544.1 - 1.2 8.9 18.8 2.4 7.9 13.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) CwfJ_C_2 PF04676.9 ETO12545.1 - 0.021 15.3 0.9 0.021 15.3 0.6 2.2 3 0 0 3 3 3 0 Protein similar to CwfJ C-terminus 2 Pkinase PF00069.20 ETO12546.1 - 3.4e-50 170.6 6.2 1.1e-46 159.1 4.3 3.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO12546.1 - 1.3e-32 112.8 1.7 8.4e-32 110.2 1.2 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO12546.1 - 0.013 14.4 0.0 0.04 12.8 0.0 1.7 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 ETO12546.1 - 0.02 14.6 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF676 PF05057.9 ETO12547.1 - 4.9e-19 68.4 0.0 9.9e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_9_N PF15420.1 ETO12547.1 - 0.15 11.8 0.7 0.29 10.8 0.1 1.7 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus DUF3671 PF12420.3 ETO12547.1 - 1 9.3 14.0 11 6.0 0.1 3.3 2 1 0 2 2 2 0 Protein of unknown function Transposase_1 PF01359.13 ETO12548.1 - 0.14 11.9 1.9 0.23 11.2 1.3 1.3 1 0 0 1 1 1 0 Transposase (partial DDE domain) GHMP_kinases_N PF00288.21 ETO12551.1 - 0.049 13.6 0.3 0.049 13.6 0.2 2.1 2 0 0 2 2 2 0 GHMP kinases N terminal domain Ank_2 PF12796.2 ETO12552.1 - 8.6e-26 90.1 3.8 5.3e-12 45.9 0.3 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO12552.1 - 1.8e-22 78.7 0.4 7.3e-11 41.9 0.1 2.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 ETO12552.1 - 1.1e-20 72.2 0.2 2.5e-07 30.1 0.1 5.2 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.1 ETO12552.1 - 6.7e-17 59.9 0.6 6.5e-05 22.7 0.1 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 ETO12552.1 - 1.7e-16 60.2 0.8 4.2e-06 27.1 0.1 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) SPRY PF00622.23 ETO12553.1 - 5.7e-05 23.1 0.0 7.7e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 SPRY domain Tubulin PF00091.20 ETO12554.1 - 1.1e-59 201.8 0.0 5e-40 137.6 0.0 3.1 2 1 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO12554.1 - 1.3e-50 170.6 0.0 2e-50 170.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain DUF788 PF05620.6 ETO12556.1 - 1.7 8.4 14.4 6.2 6.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF788) PDEase_I PF00233.14 ETO12558.1 - 4.6e-63 213.1 9.6 4.7e-35 121.4 4.3 2.4 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase 7TM_GPCR_Srsx PF10320.4 ETO12558.1 - 0.005 16.0 0.9 0.011 14.8 0.6 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx PKK PF12474.3 ETO12558.1 - 0.9 9.2 11.4 0.071 12.8 4.0 2.0 2 0 0 2 2 2 0 Polo kinase kinase FadA PF09403.5 ETO12559.1 - 0.014 15.4 0.7 0.032 14.2 0.5 1.6 1 0 0 1 1 1 0 Adhesion protein FadA DUF2127 PF09900.4 ETO12559.1 - 0.024 14.6 0.1 2.7 7.9 0.0 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2127) Reo_sigmaC PF04582.7 ETO12559.1 - 0.041 13.0 1.6 0.054 12.6 1.1 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 ETO12559.1 - 0.54 10.0 8.4 0.23 11.2 3.7 1.9 2 0 0 2 2 2 0 Tropomyosin like WXG100 PF06013.7 ETO12559.1 - 1.2 9.1 5.7 0.26 11.3 0.5 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DUF148 PF02520.12 ETO12559.1 - 1.8 8.3 9.1 5.2 6.9 0.8 2.5 3 0 0 3 3 3 0 Domain of unknown function DUF148 SPX PF03105.14 ETO12559.1 - 2.4 7.8 6.6 4.5 6.9 4.6 1.4 1 1 0 1 1 1 0 SPX domain WD40 PF00400.27 ETO12560.1 - 4.5e-17 61.2 5.8 1.8e-09 37.1 0.3 3.4 4 0 0 4 4 4 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO12560.1 - 0.012 13.8 0.7 0.043 11.9 0.1 1.8 1 1 1 2 2 2 0 Nucleoporin Nup120/160 WD40 PF00400.27 ETO12561.1 - 3.5e-155 499.0 45.8 7.5e-12 44.6 0.3 16.2 16 0 0 16 16 16 16 WD domain, G-beta repeat Nup160 PF11715.3 ETO12561.1 - 1.3e-13 50.0 27.5 0.017 13.2 0.1 11.3 2 1 6 11 11 11 7 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO12561.1 - 5.3e-11 42.5 5.2 0.042 13.5 0.0 6.6 2 2 2 6 6 6 4 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO12561.1 - 3.6e-09 36.0 20.3 3.1 7.5 0.1 10.0 10 0 0 10 10 10 2 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 ETO12561.1 - 1.7e-08 33.4 3.5 0.2 10.1 0.0 7.1 4 3 4 9 9 9 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Pentapeptide_4 PF13599.1 ETO12561.1 - 8.8e-07 28.6 1.6 1.9e-06 27.5 0.4 2.2 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETO12561.1 - 4.1e-06 25.9 2.2 8.2e-06 24.9 1.5 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Cytochrom_D1 PF02239.11 ETO12561.1 - 3.4e-05 22.3 8.8 0.015 13.6 0.2 5.1 3 3 3 6 6 6 2 Cytochrome D1 heme domain Pentapeptide_3 PF13576.1 ETO12561.1 - 0.00011 21.9 0.1 0.00054 19.7 0.1 2.3 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Nbas_N PF15492.1 ETO12561.1 - 0.00067 18.8 13.5 0.2 10.7 0.0 7.2 3 1 1 8 8 8 1 Neuroblastoma-amplified sequence, N terminal Mid2 PF04478.7 ETO12561.1 - 0.0026 17.1 21.1 0.27 10.6 0.1 7.5 6 3 3 9 9 9 2 Mid2 like cell wall stress sensor Resistin PF06954.6 ETO12561.1 - 0.05 13.8 0.1 36 4.7 0.0 4.8 4 2 2 6 6 6 0 Resistin DUF4072 PF13284.1 ETO12561.1 - 0.11 12.6 0.0 65 3.8 0.0 5.1 7 0 0 7 7 7 0 Domain of unknown function (DUF4072) RIC3 PF15361.1 ETO12562.1 - 4.4 7.5 6.6 7.8 6.7 4.6 1.4 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 BSP_II PF05432.6 ETO12563.1 - 0.00079 18.8 5.4 0.0014 17.9 3.7 1.4 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Daxx PF03344.10 ETO12563.1 - 0.076 11.4 12.3 0.11 10.9 8.5 1.2 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 ETO12563.1 - 0.1 10.4 14.3 0.17 9.7 9.9 1.2 1 0 0 1 1 1 0 Nop14-like family IFT57 PF10498.4 ETO12563.1 - 0.73 8.5 10.3 1.4 7.5 7.1 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 BUD22 PF09073.5 ETO12563.1 - 3.4 6.6 18.4 5.4 5.9 12.7 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.9 ETO12563.1 - 3.9 5.3 17.0 7.4 4.4 11.8 1.3 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.5 ETO12563.1 - 6.2 7.1 21.3 0.29 11.3 9.5 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain MIP-T3 PF10243.4 ETO12563.1 - 9.8 4.5 19.4 4.1 5.7 0.6 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Myc_N PF01056.13 ETO12564.1 - 0.84 8.7 6.9 0.9 8.6 4.8 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF4604 PF15377.1 ETO12564.1 - 6.8 6.8 20.4 7.5 6.7 14.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Menin PF05053.8 ETO12564.1 - 8.7 4.3 16.5 9.5 4.2 11.4 1.0 1 0 0 1 1 1 0 Menin RUN PF02759.14 ETO12565.1 - 0.0053 16.5 0.3 0.0073 16.0 0.2 1.2 1 0 0 1 1 1 1 RUN domain SLAP PF03217.9 ETO12567.1 - 0.025 14.7 0.8 0.06 13.5 0.6 1.5 1 0 0 1 1 1 0 Bacterial surface layer protein Tmpp129 PF10272.4 ETO12568.1 - 0.095 11.4 0.9 0.16 10.7 0.6 1.3 1 0 0 1 1 1 0 Putative transmembrane protein precursor SH PF01445.12 ETO12568.1 - 5.6 6.6 14.9 0.24 11.0 0.9 3.8 3 1 0 3 3 3 0 Viral small hydrophobic protein DUF912 PF06024.7 ETO12569.1 - 0.047 13.7 3.4 1.2 9.2 0.8 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1183 PF06682.7 ETO12569.1 - 0.074 12.6 3.6 0.45 10.0 2.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) DUF897 PF05982.7 ETO12569.1 - 0.12 11.0 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF897) TMEM51 PF15345.1 ETO12569.1 - 0.26 10.9 3.3 0.65 9.6 1.6 2.0 1 1 0 1 1 1 0 Transmembrane protein 51 TSCPD PF12637.2 ETO12570.1 - 0.11 12.5 0.1 9.7 6.2 0.0 2.3 2 0 0 2 2 2 0 TSCPD domain SGS PF05002.10 ETO12570.1 - 0.64 9.8 3.9 1.1 8.9 1.3 2.3 2 1 1 3 3 3 0 SGS domain Pox_polyA_pol PF03296.8 ETO12570.1 - 2.9 7.4 5.5 12 5.4 0.5 2.1 2 0 0 2 2 2 0 Poxvirus poly(A) polymerase nucleotidyltransferase domain Herpes_IE1 PF07340.6 ETO12571.1 - 0.092 11.1 0.0 0.13 10.6 0.0 1.2 1 0 0 1 1 1 0 Cytomegalovirus IE1 protein AAA_33 PF13671.1 ETO12572.1 - 0.027 14.3 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_ligase PF09414.5 ETO12573.1 - 1e-07 31.9 0.1 2.1e-07 30.9 0.0 1.6 1 1 0 1 1 1 1 RNA ligase DNA_ligase_A_M PF01068.16 ETO12573.1 - 8.9e-05 21.9 0.0 0.00013 21.3 0.0 1.2 1 0 0 1 1 1 1 ATP dependent DNA ligase domain Epimerase PF01370.16 ETO12574.1 - 3.9e-39 134.4 0.0 5.5e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ETO12574.1 - 4e-06 25.9 0.0 0.00086 18.3 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 ETO12574.1 - 0.00015 20.5 0.0 0.00034 19.4 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 ETO12574.1 - 0.0014 17.6 0.0 0.011 14.5 0.0 2.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 ETO12574.1 - 0.02 14.9 0.0 0.18 11.7 0.0 2.1 1 1 0 1 1 1 0 NADH(P)-binding 2-Hacid_dh_C PF02826.14 ETO12574.1 - 0.037 13.1 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 ETO12574.1 - 0.039 13.4 0.0 0.08 12.3 0.0 1.4 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RmlD_sub_bind PF04321.12 ETO12574.1 - 0.04 12.8 0.0 0.32 9.8 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain adh_short PF00106.20 ETO12574.1 - 0.04 13.8 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase Spore_coat_CotO PF14153.1 ETO12575.1 - 0.0064 15.9 12.4 0.012 15.0 8.6 1.4 1 1 0 1 1 1 1 Spore coat protein CotO TFIIF_alpha PF05793.7 ETO12575.1 - 0.11 10.8 19.0 0.1 10.9 13.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Daxx PF03344.10 ETO12575.1 - 4.9 5.5 23.8 6.5 5.1 16.5 1.3 1 0 0 1 1 1 0 Daxx Family PBP1_TM PF14812.1 ETO12576.1 - 7.9 6.8 22.2 3.6 7.9 5.8 3.2 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4064 PF13273.1 ETO12577.1 - 0.12 12.5 4.2 1.5 8.9 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF2547 PF10818.3 ETO12578.1 - 0.018 15.6 6.9 0.04 14.5 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2547) Folliculin PF11704.3 ETO12578.1 - 0.17 11.4 6.0 4.8 6.7 3.8 2.3 1 1 1 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Med3 PF11593.3 ETO12578.1 - 2 7.5 8.3 3.3 6.8 5.8 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TSA PF03249.8 ETO12578.1 - 4.7 5.6 7.0 5.9 5.3 4.9 1.1 1 0 0 1 1 1 0 Type specific antigen PH PF00169.24 ETO12579.1 - 8.7e-14 51.5 3.3 1.1e-13 51.2 2.3 1.2 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 ETO12579.1 - 7.8e-06 26.0 2.0 1.1e-05 25.5 1.4 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 ETO12579.1 - 0.017 15.3 5.0 0.22 11.7 3.4 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain 2-Hacid_dh PF00389.25 ETO12580.1 - 5.1e-17 61.5 0.0 5.9e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 2-Hacid_dh_C PF02826.14 ETO12580.1 - 4.2e-13 48.8 0.1 6.4e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 ETO12580.1 - 0.0036 17.1 0.1 0.0075 16.1 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.1 ETO12580.1 - 0.01 15.8 0.3 0.049 13.6 0.0 2.0 2 0 0 2 2 2 0 NADH(P)-binding Pyr_redox PF00070.22 ETO12580.1 - 0.065 13.6 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 ETO12580.1 - 0.078 13.2 0.1 0.21 11.8 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 ETO12580.1 - 0.16 11.6 1.0 0.26 10.9 0.1 1.9 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase PF00069.20 ETO12581.1 - 4.6e-46 157.0 0.0 5.3e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO12581.1 - 1.2e-16 60.5 0.0 2.1e-16 59.7 0.0 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 ETO12581.1 - 0.052 12.6 0.0 0.076 12.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pantoate_transf PF02548.10 ETO12582.1 - 0.077 12.1 0.1 0.1 11.7 0.1 1.1 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase PBP_sp32 PF07222.7 ETO12582.1 - 1.8 7.6 4.3 2.8 7.0 3.0 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 tRNA-synt_1d PF00750.14 ETO12584.1 - 1.4e-17 63.5 0.0 1.4e-17 63.5 0.0 3.1 2 1 0 3 3 3 2 tRNA synthetases class I (R) tRNA_bind PF01588.15 ETO12584.1 - 5.8e-06 26.0 0.0 2.9e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Putative tRNA binding domain Ycf1 PF05758.7 ETO12584.1 - 0.71 7.5 14.3 0.94 7.1 9.9 1.1 1 0 0 1 1 1 0 Ycf1 GAGA_bind PF06217.7 ETO12584.1 - 0.87 9.4 10.8 1.4 8.7 7.5 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DDHD PF02862.12 ETO12584.1 - 4.4 7.0 10.7 8.4 6.1 7.4 1.4 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 ETO12584.1 - 5.3 6.8 14.6 8.7 6.1 10.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TMF_TATA_bd PF12325.3 ETO12585.1 - 0.017 14.8 11.0 0.017 14.8 7.6 3.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF1411 PF07199.6 ETO12585.1 - 0.19 11.1 3.2 0.18 11.2 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1411) DEAD PF00270.24 ETO12585.1 - 1.1 8.7 9.3 1.8 8.0 6.1 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase DUF972 PF06156.8 ETO12585.1 - 6.7 7.1 34.4 1.1 9.6 0.5 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF972) Merozoite_SPAM PF07133.6 ETO12586.1 - 0.74 9.6 15.0 0.86 9.4 10.4 1.0 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) YqfQ PF14181.1 ETO12586.1 - 9.5 6.2 12.4 21 5.0 8.6 1.6 1 1 0 1 1 1 0 YqfQ-like protein Hydrolase_like PF13242.1 ETO12587.1 - 0.0038 16.9 0.0 0.0075 15.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Adaptin_N PF01602.15 ETO12588.1 - 4.7e-116 388.1 13.7 5.8e-116 387.8 9.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 ETO12588.1 - 6.7e-15 55.0 0.0 2.8e-14 53.0 0.0 2.2 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 ETO12588.1 - 3.2e-14 53.2 0.3 1.3e-13 51.2 0.1 2.3 2 0 0 2 2 2 1 Adaptin C-terminal domain HEAT PF02985.17 ETO12588.1 - 0.31 11.2 1.5 32 4.9 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat ADP_ribosyl_GH PF03747.9 ETO12589.1 - 1.3e-35 123.5 0.0 1.7e-35 123.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase adh_short PF00106.20 ETO12590.1 - 3.1e-28 98.7 0.0 4.3e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETO12590.1 - 3.1e-10 40.2 0.0 6.7e-10 39.1 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETO12590.1 - 3.6e-08 33.2 0.0 1e-07 31.8 0.0 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 ETO12590.1 - 0.00019 20.9 0.0 0.00038 19.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RNA_pol_Rpb4 PF03874.11 ETO12590.1 - 0.047 13.7 0.3 0.11 12.5 0.1 1.6 2 0 0 2 2 2 0 RNA polymerase Rpb4 2-Hacid_dh_C PF02826.14 ETO12590.1 - 0.083 12.0 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 ETO12590.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding Claudin_2 PF13903.1 ETO12591.1 - 0.0016 18.1 0.0 0.0016 18.1 0.0 2.1 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction TLP-20 PF06088.6 ETO12591.1 - 0.0067 16.1 1.7 0.0067 16.1 1.2 2.0 2 0 0 2 2 2 1 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Menin PF05053.8 ETO12591.1 - 0.055 11.6 0.0 0.055 11.6 0.0 1.1 1 0 0 1 1 1 0 Menin Lipl32 PF12103.3 ETO12591.1 - 0.14 11.6 1.1 0.17 11.3 0.1 1.6 2 0 0 2 2 2 0 Surface lipoprotein of Spirochaetales order DUF2254 PF10011.4 ETO12591.1 - 0.15 10.5 0.5 0.2 10.0 0.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Dppa2_A PF14049.1 ETO12592.1 - 3.2 7.6 5.8 1.1 9.1 1.3 2.0 1 1 1 2 2 2 0 Dppa2/4 conserved region in higher vertebrates Ribosomal_L6e PF01159.14 ETO12592.1 - 5.8 7.1 9.4 1.5 9.1 0.5 2.9 2 1 1 3 3 3 0 Ribosomal protein L6e Sulfotransfer_3 PF13469.1 ETO12593.1 - 0.029 15.3 0.5 0.071 14.0 0.3 1.6 1 1 0 1 1 1 0 Sulfotransferase family MIF4G_like_2 PF09090.6 ETO12595.1 - 3.9e-09 36.1 11.6 8.4e-09 35.0 2.1 2.3 2 0 0 2 2 2 2 MIF4G like Peptidase_U4 PF03419.8 ETO12598.1 - 7.5 5.5 19.6 2.5e+02 0.5 13.6 2.2 1 1 0 1 1 1 0 Sporulation factor SpoIIGA Tudor-knot PF11717.3 ETO12599.1 - 0.0024 17.5 0.6 0.0087 15.7 0.1 2.2 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain DUF1956 PF09209.6 ETO12599.1 - 0.017 15.0 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1956) Fer2 PF00111.22 ETO12600.1 - 0.00014 21.5 0.0 0.00026 20.6 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain TINF2_N PF14973.1 ETO12600.1 - 0.12 12.4 0.5 0.17 11.9 0.3 1.2 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus Tsg PF04668.7 ETO12601.1 - 0.013 15.6 0.1 0.022 14.9 0.1 1.3 1 0 0 1 1 1 0 Twisted gastrulation (Tsg) protein conserved region DUF433 PF04255.9 ETO12601.1 - 0.046 13.1 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF433) Glyco_hydro_18 PF00704.23 ETO12602.1 - 1.8e-06 27.6 0.5 3.2e-06 26.8 0.3 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 SpoVAD PF07451.6 ETO12604.1 - 0.078 11.4 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) Prok-RING_2 PF14445.1 ETO12604.1 - 0.62 10.0 7.2 4.3 7.3 1.8 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 FinO_N PF12602.3 ETO12605.1 - 0.09 13.0 0.0 3.7 7.9 0.0 2.2 2 0 0 2 2 2 0 Fertility inhibition protein N terminal C2 PF00168.25 ETO12606.1 - 0.00083 19.1 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain Gp_UL130 PF11668.3 ETO12606.1 - 0.048 13.1 0.1 0.16 11.4 0.0 1.8 2 0 0 2 2 2 0 HCMV glycoprotein pUL130 ETRAMP PF09716.5 ETO12608.1 - 0.034 14.0 0.0 0.095 12.6 0.0 1.8 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) zf-C2H2_3 PF13878.1 ETO12610.1 - 0.12 11.9 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO RRN3 PF05327.6 ETO12611.1 - 0.0088 14.2 2.5 0.0096 14.0 1.7 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 DUF1759 PF03564.10 ETO12611.1 - 0.02 14.7 5.5 0.022 14.5 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) Dehydrin PF00257.14 ETO12611.1 - 0.038 14.3 9.8 0.047 14.0 6.8 1.1 1 0 0 1 1 1 0 Dehydrin DUF3347 PF11827.3 ETO12611.1 - 0.046 13.7 4.3 0.053 13.5 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) PDCD2_C PF04194.8 ETO12611.1 - 0.06 12.9 4.5 0.061 12.9 3.1 1.1 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain OATP PF03137.15 ETO12611.1 - 0.061 11.3 3.3 0.066 11.2 2.3 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Glyco_transf_15 PF01793.11 ETO12611.1 - 0.084 11.7 3.1 0.087 11.7 2.2 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase FCP1_C PF09309.5 ETO12611.1 - 0.1 11.9 6.4 0.11 11.8 4.5 1.1 1 0 0 1 1 1 0 FCP1, C-terminal RR_TM4-6 PF06459.7 ETO12611.1 - 0.1 12.4 5.9 0.1 12.4 4.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF912 PF06024.7 ETO12611.1 - 0.11 12.5 1.5 0.12 12.4 1.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) F-112 PF09645.5 ETO12611.1 - 0.13 12.1 9.1 0.18 11.7 6.3 1.2 1 0 0 1 1 1 0 F-112 protein Peptidase_S49_N PF08496.5 ETO12611.1 - 0.2 11.4 6.4 0.25 11.1 4.5 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4199 PF13858.1 ETO12611.1 - 0.21 11.5 2.4 0.24 11.3 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) FimP PF09766.4 ETO12611.1 - 0.24 10.4 11.0 0.27 10.2 7.6 1.1 1 0 0 1 1 1 0 Fms-interacting protein Dala_Dala_lig_N PF01820.16 ETO12611.1 - 0.27 11.5 2.3 0.28 11.5 1.6 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Pex26 PF07163.7 ETO12611.1 - 0.27 10.0 2.6 0.27 10.1 1.8 1.1 1 0 0 1 1 1 0 Pex26 protein DUF106 PF01956.11 ETO12611.1 - 0.33 10.4 6.2 0.38 10.2 4.3 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 Folliculin PF11704.3 ETO12611.1 - 0.34 10.4 4.9 0.38 10.3 3.4 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Blt1 PF12754.2 ETO12611.1 - 0.35 10.4 4.7 0.35 10.4 3.3 1.1 1 0 0 1 1 1 0 Cell-cycle control medial ring component EIIBC-GUT_N PF03612.9 ETO12611.1 - 0.38 10.3 3.5 0.4 10.2 2.4 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Peptidase_C58 PF03543.9 ETO12611.1 - 0.72 9.3 7.0 0.8 9.1 4.9 1.1 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen RNA_pol_Rpb1_2 PF00623.15 ETO12611.1 - 0.93 9.4 3.8 1.1 9.2 2.7 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 2 Nucleoside_tran PF01733.13 ETO12611.1 - 1 8.4 3.9 1.2 8.2 2.7 1.0 1 0 0 1 1 1 0 Nucleoside transporter YqfQ PF14181.1 ETO12611.1 - 1.3 9.0 9.4 1.5 8.8 6.5 1.1 1 0 0 1 1 1 0 YqfQ-like protein BAF1_ABF1 PF04684.8 ETO12611.1 - 1.8 7.2 9.6 1.9 7.2 6.7 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4407 PF14362.1 ETO12611.1 - 2.9 6.7 6.1 3.3 6.5 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF874 PF05917.6 ETO12611.1 - 3.4 6.4 14.7 3.5 6.3 10.2 1.0 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) DUF4175 PF13779.1 ETO12611.1 - 4.6 4.8 14.5 5.1 4.6 10.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SprA-related PF12118.3 ETO12611.1 - 6.4 6.0 15.6 7.2 5.8 10.8 1.0 1 0 0 1 1 1 0 SprA-related family Med3 PF11593.3 ETO12611.1 - 7.7 5.6 10.4 9.2 5.3 7.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal U1snRNP70_N PF12220.3 ETO12611.1 - 8.7 6.7 12.3 11 6.3 8.5 1.2 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal HSP70 PF00012.15 ETO12612.1 - 2.2e-62 210.8 2.5 1.4e-35 122.3 0.1 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 ETO12612.1 - 0.025 13.1 0.1 0.12 10.9 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein Dapper PF15268.1 ETO12613.1 - 9.8 4.8 39.8 14 4.3 27.6 1.1 1 0 0 1 1 1 0 Dapper adh_short PF00106.20 ETO12614.1 - 2.7e-08 33.9 0.0 1.1e-07 31.9 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase Hist_deacetyl PF00850.14 ETO12615.1 - 3.8e-70 236.6 0.2 2.1e-41 142.2 0.0 2.6 2 0 0 2 2 2 2 Histone deacetylase domain Methyltransf_18 PF12847.2 ETO12615.1 - 4.1e-09 36.9 0.0 1.3e-08 35.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO12615.1 - 2e-08 34.5 0.0 6.1e-08 33.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO12615.1 - 9.9e-07 28.4 0.1 1.6e-05 24.5 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETO12615.1 - 3.9e-06 27.2 0.0 1.1e-05 25.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 ETO12615.1 - 8.9e-06 24.9 0.0 1.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.1 ETO12615.1 - 8.1e-05 22.3 0.0 0.00021 21.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETO12615.1 - 0.0032 17.4 0.0 0.0064 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.11 ETO12616.1 - 1.1e-64 218.3 3.0 3.1e-48 164.3 0.0 2.1 1 1 0 2 2 2 2 mRNA capping enzyme Methyltransf_12 PF08242.7 ETO12616.1 - 0.0008 19.8 0.0 0.0023 18.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETO12616.1 - 0.0019 17.9 0.0 0.0036 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO12616.1 - 0.024 15.1 0.0 0.041 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 ETO12616.1 - 0.026 15.0 0.0 0.068 13.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Minor_capsid_1 PF10665.4 ETO12616.1 - 0.048 13.5 0.5 0.13 12.1 0.4 1.7 1 0 0 1 1 1 0 Minor capsid protein NNMT_PNMT_TEMT PF01234.12 ETO12616.1 - 0.048 12.6 0.0 0.1 11.5 0.0 1.5 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family O-FucT PF10250.4 ETO12617.1 - 2.7e-16 59.6 3.5 1.3e-13 50.7 2.4 2.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Pkinase PF00069.20 ETO12618.1 - 1.1e-42 145.9 5.7 1.6e-23 83.1 3.6 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO12618.1 - 1.1e-14 54.1 2.4 9.4e-09 34.7 0.3 3.8 3 1 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.1 ETO12618.1 - 0.00012 21.1 0.4 0.00087 18.3 0.3 2.1 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 ETO12618.1 - 0.00025 20.4 2.8 0.00094 18.5 2.0 2.0 1 1 0 1 1 1 1 RIO1 family APH PF01636.18 ETO12618.1 - 0.062 13.0 1.1 0.095 12.4 0.4 1.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family VGCC_alpha2 PF08473.6 ETO12619.1 - 0.023 14.4 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 Neuronal voltage-dependent calcium channel alpha 2acd BLVR PF06375.6 ETO12619.1 - 1.8 8.3 16.0 0.1 12.3 4.6 2.1 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Herpes_DNAp_acc PF04929.7 ETO12619.1 - 7.2 5.4 13.6 0.078 11.9 3.9 1.6 2 0 0 2 2 2 0 Herpes DNA replication accessory factor GNT-I PF03071.10 ETO12620.1 - 6.7e-89 298.3 4.4 3.4e-88 296.0 3.1 1.9 1 1 0 1 1 1 1 GNT-I family Peptidase_M24 PF00557.19 ETO12621.1 - 1.2e-33 116.4 0.1 2.1e-33 115.6 0.0 1.4 1 1 0 1 1 1 1 Metallopeptidase family M24 DUF3793 PF12672.2 ETO12621.1 - 0.001 18.6 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3793) RNase_T PF00929.19 ETO12622.1 - 2.2e-18 67.0 3.7 4.8e-09 36.7 0.0 2.9 3 0 0 3 3 3 2 Exonuclease DUF3577 PF12101.3 ETO12622.1 - 0.0078 16.1 0.3 0.79 9.6 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3577) Glu_synthase PF01645.12 ETO12622.1 - 0.52 9.1 3.6 8.9 5.1 0.2 2.2 2 0 0 2 2 2 0 Conserved region in glutamate synthase E1-E2_ATPase PF00122.15 ETO12623.1 - 3.6 6.5 6.1 0.21 10.6 0.5 1.6 2 0 0 2 2 2 0 E1-E2 ATPase GPS PF01825.16 ETO12624.1 - 2.1e-07 30.9 6.0 2.1e-07 30.9 4.1 2.8 2 1 1 3 3 3 1 Latrophilin/CL-1-like GPS domain GLE1 PF07817.8 ETO12626.1 - 0.0044 15.9 5.8 0.0049 15.8 2.1 1.9 1 1 1 2 2 2 1 GLE1-like protein Spore_III_AF PF09581.5 ETO12626.1 - 0.044 13.6 1.3 2.4 8.0 0.4 2.3 1 1 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) Ustilago_mating PF05722.7 ETO12629.1 - 0.06 12.6 0.6 0.087 12.1 0.4 1.2 1 0 0 1 1 1 0 Ustilago B locus mating-type protein Baculo_PEP_N PF04512.7 ETO12630.1 - 0.048 13.6 0.0 0.094 12.7 0.0 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, N terminus DUF3608 PF12257.3 ETO12631.1 - 1.9e-40 138.5 7.7 3e-20 72.2 1.4 4.4 4 0 0 4 4 4 4 Protein of unknown function (DUF3608) WD40 PF00400.27 ETO12632.1 - 4.6e-149 479.6 34.9 5.4e-11 41.9 0.1 16.2 16 0 0 16 16 16 15 WD domain, G-beta repeat PD40 PF07676.7 ETO12632.1 - 7.2e-06 25.5 20.1 3.3 7.4 0.0 9.2 9 0 0 9 9 9 3 WD40-like Beta Propeller Repeat Pentapeptide PF00805.17 ETO12632.1 - 2.7e-05 23.2 0.2 6e-05 22.1 0.1 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) PQQ_2 PF13360.1 ETO12632.1 - 7.3e-05 22.3 1.7 0.073 12.5 0.0 3.9 2 1 0 3 3 3 1 PQQ-like domain SGL PF08450.7 ETO12632.1 - 0.00014 21.3 1.8 14 4.9 0.0 5.6 4 2 1 6 6 6 0 SMP-30/Gluconolaconase/LRE-like region Pentapeptide_4 PF13599.1 ETO12632.1 - 0.00016 21.4 0.1 0.00052 19.7 0.1 1.9 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Cytochrom_D1 PF02239.11 ETO12632.1 - 0.00037 18.8 2.2 1.3 7.2 0.1 4.5 3 1 1 4 4 4 1 Cytochrome D1 heme domain DUF1652 PF07865.6 ETO12632.1 - 0.00051 19.5 0.3 54 3.4 0.0 7.3 11 0 0 11 11 11 0 Protein of unknown function (DUF1652) DUF1258 PF06869.7 ETO12632.1 - 0.001 18.2 6.7 1 8.3 0.0 5.0 4 1 1 6 6 6 1 Protein of unknown function (DUF1258) NYD-SP28_assoc PF14775.1 ETO12632.1 - 0.0067 16.0 7.5 77 3.1 0.0 8.1 11 0 0 11 11 11 0 Sperm tail C-terminal domain Pentapeptide_3 PF13576.1 ETO12632.1 - 0.0069 16.2 1.0 0.032 14.1 0.7 2.2 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Ras PF00071.17 ETO12634.1 - 4.3e-21 74.9 0.5 5.1e-21 74.7 0.4 1.1 1 0 0 1 1 1 1 Ras family Galactosyl_T PF01762.16 ETO12634.1 - 0.053 13.1 0.0 0.064 12.8 0.0 1.1 1 0 0 1 1 1 0 Galactosyltransferase SNF2_N PF00176.18 ETO12634.1 - 0.1 11.3 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain p450 PF00067.17 ETO12636.1 - 8.4e-49 166.3 0.0 1e-48 166.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ras PF00071.17 ETO12637.1 - 1.2e-11 44.2 0.0 1.7e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Ras family DUF2633 PF11119.3 ETO12637.1 - 0.019 14.6 0.2 0.04 13.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) Miro PF08477.8 ETO12637.1 - 0.058 13.8 0.0 0.098 13.1 0.0 1.3 1 0 0 1 1 1 0 Miro-like protein SPC25 PF06703.6 ETO12637.1 - 0.81 9.2 4.6 0.12 11.9 0.5 1.5 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF843 PF05814.6 ETO12637.1 - 2.3 8.0 6.8 0.3 10.8 0.1 2.2 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) PDR_CDR PF06422.7 ETO12637.1 - 8.9 6.0 7.2 0.49 10.0 0.5 1.9 2 0 0 2 2 2 0 CDR ABC transporter DcpS_C PF11969.3 ETO12638.1 - 0.00018 21.6 0.1 0.00061 19.9 0.0 1.9 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 ETO12638.1 - 0.032 14.7 0.0 0.071 13.6 0.0 1.5 1 0 0 1 1 1 0 HIT domain adh_short PF00106.20 ETO12639.1 - 5.9e-21 75.1 0.0 1e-20 74.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETO12639.1 - 7.7e-14 51.7 0.0 1e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETO12639.1 - 1.3e-09 38.2 0.2 2.1e-09 37.5 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.7 ETO12639.1 - 2.1e-06 26.8 0.1 2.8e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 ETO12639.1 - 5.1e-06 26.0 1.4 8.9e-06 25.3 1.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETO12639.1 - 6.1e-06 26.3 0.6 0.00028 20.9 0.0 2.5 1 1 1 2 2 2 1 NADH(P)-binding FlpD PF02662.11 ETO12639.1 - 0.00037 20.1 0.7 0.45 10.2 0.2 2.3 2 0 0 2 2 2 2 Methyl-viologen-reducing hydrogenase, delta subunit NmrA PF05368.8 ETO12639.1 - 0.017 14.4 0.1 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family TrkA_N PF02254.13 ETO12639.1 - 0.046 13.7 1.3 9.7 6.2 0.1 3.3 1 1 2 3 3 3 0 TrkA-N domain RGS PF00615.14 ETO12640.1 - 5.5e-06 26.4 1.2 4.7e-05 23.4 0.8 2.3 1 1 0 1 1 1 1 Regulator of G protein signaling domain CDI PF02234.14 ETO12640.1 - 0.029 14.1 0.2 0.029 14.1 0.1 3.8 3 0 0 3 3 3 0 Cyclin-dependent kinase inhibitor Fzo_mitofusin PF04799.8 ETO12640.1 - 2.3 7.5 8.3 5 6.4 5.8 1.5 1 0 0 1 1 1 0 fzo-like conserved region AAA PF00004.24 ETO12641.1 - 2.8e-25 89.0 0.0 4.5e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 ETO12641.1 - 1.9e-06 28.7 0.3 3.9e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 ETO12641.1 - 5.5e-06 26.1 0.0 1.4e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 ETO12641.1 - 8.1e-06 25.9 0.3 0.0024 17.8 0.1 2.5 1 1 2 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 ETO12641.1 - 2.9e-05 23.2 0.0 4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 ETO12641.1 - 0.00017 21.9 1.3 0.0024 18.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 ETO12641.1 - 0.00023 19.9 0.0 0.00029 19.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 ETO12641.1 - 0.00029 20.3 0.0 0.00046 19.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 ETO12641.1 - 0.00029 20.9 0.1 0.0098 16.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 ETO12641.1 - 0.00042 20.2 0.0 0.0028 17.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 ETO12641.1 - 0.00049 19.2 0.0 0.00084 18.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 ETO12641.1 - 0.0005 19.7 0.4 0.00091 18.9 0.3 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 ETO12641.1 - 0.0011 18.8 0.1 0.0046 16.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 ETO12641.1 - 0.002 18.1 0.1 0.0044 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 ETO12641.1 - 0.0027 17.1 0.8 0.0099 15.2 0.3 1.9 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 ETO12641.1 - 0.0036 16.4 0.3 0.0077 15.4 0.2 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 ETO12641.1 - 0.0047 16.8 0.0 0.0094 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 ETO12641.1 - 0.005 16.7 0.1 0.23 11.2 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase Sigma54_activat PF00158.21 ETO12641.1 - 0.005 16.3 0.0 0.015 14.7 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain PhoH PF02562.11 ETO12641.1 - 0.0073 15.5 0.2 0.043 13.0 0.0 2.0 2 0 0 2 2 2 1 PhoH-like protein Cytochrom_C550 PF14495.1 ETO12641.1 - 0.012 15.0 0.1 0.019 14.4 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c-550 domain Sigma54_activ_2 PF14532.1 ETO12641.1 - 0.014 15.4 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 ETO12641.1 - 0.037 13.1 0.0 0.12 11.4 0.0 1.9 2 0 0 2 2 2 0 KaiC NACHT PF05729.7 ETO12641.1 - 0.072 12.7 0.2 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 NACHT domain T2SE PF00437.15 ETO12641.1 - 0.078 11.8 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 ETO12641.1 - 0.12 12.6 0.2 0.26 11.5 0.0 1.6 2 0 0 2 2 1 0 ABC transporter Spt5_N PF11942.3 ETO12641.1 - 0.25 11.9 13.6 3.7 8.2 9.5 2.1 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal PT PF04886.7 ETO12642.1 - 1.1e-07 31.0 59.8 0.0012 18.0 11.6 3.9 1 1 2 3 3 3 3 PT repeat Beta_helix PF13229.1 ETO12642.1 - 0.00098 18.9 61.9 0.0031 17.2 20.0 8.7 1 1 3 6 6 6 4 Right handed beta helix region Peptidase_M41 PF01434.13 ETO12643.1 - 1.5e-57 194.5 0.5 1.5e-55 188.0 0.4 2.1 1 1 0 1 1 1 1 Peptidase family M41 zf-MYND PF01753.13 ETO12647.1 - 2.9e-06 27.0 9.7 2.9e-06 27.0 6.7 2.8 3 0 0 3 3 3 1 MYND finger LRR_6 PF13516.1 ETO12647.1 - 2.6e-05 23.8 8.6 0.075 13.1 0.8 4.3 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.2 ETO12647.1 - 0.0012 18.4 1.1 0.17 11.5 0.1 3.4 2 2 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETO12647.1 - 0.02 14.8 5.6 42 4.7 0.6 4.5 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 ETO12647.1 - 0.69 10.3 7.3 24 5.7 0.1 4.6 4 0 0 4 4 4 0 Leucine rich repeat LRR_8 PF13855.1 ETO12647.1 - 1.2 8.9 6.4 16 5.3 0.3 4.2 1 1 3 4 4 4 0 Leucine rich repeat JAB PF01398.16 ETO12649.1 - 0.0066 16.1 0.7 0.023 14.4 0.5 1.9 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease TMEM223 PF14640.1 ETO12650.1 - 0.07 13.0 0.3 0.086 12.7 0.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 223 RNA_pol_Rpb1_3 PF04983.13 ETO12651.1 - 0.051 13.2 0.1 0.13 11.9 0.1 1.9 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 3 BBP1_C PF15272.1 ETO12653.1 - 0.00024 20.7 12.8 0.00024 20.7 8.9 4.3 2 1 2 4 4 4 1 Spindle pole body component BBP1, C-terminal DUF373 PF04123.8 ETO12653.1 - 0.19 10.7 0.9 0.32 9.9 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF3608 PF12257.3 ETO12654.1 - 0.099 11.5 3.4 0.17 10.7 2.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3608) CRAL_TRIO PF00650.15 ETO12655.1 - 5.3e-07 29.2 0.1 1.1e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain Period_C PF12114.3 ETO12655.1 - 0.097 12.2 0.0 0.097 12.2 0.0 2.7 3 1 0 3 3 3 0 Period protein 2/3C-terminal region ProRS-C_1 PF09180.6 ETO12657.1 - 1.9e-22 78.9 0.2 5.1e-22 77.5 0.0 1.8 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.15 ETO12657.1 - 3.1e-08 33.4 0.2 1.1e-07 31.6 0.0 2.0 3 0 0 3 3 3 1 Anticodon binding domain Amnionless PF14828.1 ETO12658.1 - 0.022 13.2 0.1 0.023 13.1 0.1 1.0 1 0 0 1 1 1 0 Amnionless TAN PF11640.3 ETO12658.1 - 0.025 14.3 2.7 0.044 13.5 1.9 1.4 1 1 0 1 1 1 0 Telomere-length maintenance and DNA damage repair Merozoite_SPAM PF07133.6 ETO12658.1 - 0.35 10.7 3.6 5 7.0 0.4 2.1 1 1 1 2 2 2 0 Merozoite surface protein (SPAM) DUF3682 PF12446.3 ETO12659.1 - 0.28 11.4 9.4 0.33 11.2 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Ribosomal_60s PF00428.14 ETO12659.1 - 2.5 8.5 12.7 2.9 8.3 8.8 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Med2 PF11214.3 ETO12659.1 - 5 7.1 10.7 6 6.9 7.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 2 eIF3_subunit PF08597.5 ETO12661.1 - 0.00021 20.9 27.8 0.0038 16.8 19.3 2.2 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit Ndc1_Nup PF09531.5 ETO12661.1 - 1.1 7.6 3.9 1.2 7.4 2.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RNA_pol_Rpb1_5 PF04998.12 ETO12662.1 - 2.3e-96 322.3 0.0 4.1e-96 321.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 ETO12662.1 - 8e-66 221.0 0.0 3.3e-65 219.0 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.7 ETO12662.1 - 2e-56 191.6 0.1 6.5e-56 190.0 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_6 PF04992.9 ETO12662.1 - 8.2e-50 169.1 0.0 2.4e-49 167.6 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 ETO12662.1 - 9.2e-48 161.9 0.0 3.5e-47 160.0 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 ETO12662.1 - 5.2e-38 129.8 0.1 9.7e-38 128.9 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 ETO12662.1 - 8.7e-35 118.7 0.4 2.1e-34 117.5 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 ETO12662.1 - 1.9e-05 24.3 103.8 0.15 12.2 5.5 6.6 6 0 0 6 6 6 5 RNA polymerase Rpb1 C-terminal repeat WD40 PF00400.27 ETO12663.1 - 6.2e-26 89.3 1.5 1.3e-09 37.5 0.2 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO12663.1 - 0.16 10.6 8.0 1.3 7.6 0.3 2.7 1 1 2 3 3 3 0 Nup133 N terminal like Big_2 PF02368.13 ETO12663.1 - 0.6 10.0 3.1 0.62 9.9 0.4 2.3 2 1 0 2 2 2 0 Bacterial Ig-like domain (group 2) Pkinase PF00069.20 ETO12664.1 - 7.3e-08 31.8 0.6 9.6e-07 28.1 0.4 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO12664.1 - 0.0018 17.3 0.5 0.0064 15.5 0.3 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PAC2 PF09754.4 ETO12665.1 - 1.6e-06 28.1 0.0 2.2e-05 24.4 0.0 2.1 1 1 0 1 1 1 1 PAC2 family KR PF08659.5 ETO12665.1 - 0.037 13.6 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 KR domain DUF218 PF02698.12 ETO12665.1 - 0.079 12.4 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 DUF218 domain Fungal_trans PF04082.13 ETO12665.1 - 0.08 11.8 0.1 0.21 10.4 0.0 1.6 2 0 0 2 2 2 0 Fungal specific transcription factor domain WD40 PF00400.27 ETO12666.1 - 4.9e-72 235.4 21.6 4.4e-14 51.7 0.0 7.0 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO12666.1 - 6e-11 42.4 0.0 0.00086 19.0 0.0 3.8 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO12666.1 - 1.5e-08 33.2 1.5 0.031 12.4 0.0 3.9 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO12666.1 - 3.5e-05 22.7 4.8 0.046 12.4 0.1 3.9 1 1 2 3 3 3 3 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO12666.1 - 4e-05 22.0 0.4 0.2 9.9 0.1 2.8 1 1 2 3 3 3 3 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO12666.1 - 0.00078 18.6 0.6 0.11 11.5 0.1 3.7 2 1 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 ETO12666.1 - 0.0021 17.5 0.2 0.03 13.7 0.2 2.7 1 1 0 1 1 1 1 PQQ-like domain Hira PF07569.6 ETO12666.1 - 0.0069 15.6 1.4 3.3 6.8 0.1 4.0 1 1 5 6 6 6 1 TUP1-like enhancer of split Resistin PF06954.6 ETO12666.1 - 0.011 16.0 9.2 0.57 10.4 0.3 5.1 2 1 5 7 7 7 0 Resistin PD40 PF07676.7 ETO12666.1 - 0.031 13.9 8.3 2.6 7.8 0.1 5.0 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 ETO12666.1 - 0.12 11.6 2.9 36 3.8 0.0 4.3 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature PUB PF09409.5 ETO12667.1 - 0.01 15.5 0.4 0.01 15.5 0.3 2.3 2 1 0 2 2 2 0 PUB domain CW_binding_1 PF01473.15 ETO12667.1 - 0.11 12.6 2.7 0.22 11.6 1.9 1.5 1 0 0 1 1 1 0 Putative cell wall binding repeat Peptidase_C71 PF12386.3 ETO12667.1 - 0.12 11.8 2.0 0.2 11.0 1.3 1.5 1 1 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei Sec8_exocyst PF04048.9 ETO12668.1 - 0.0027 17.3 2.4 0.022 14.3 0.2 2.4 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain TyeA PF09059.5 ETO12668.1 - 0.06 13.2 0.0 0.2 11.5 0.0 1.9 1 0 0 1 1 1 0 TyeA Tubulin_C PF03953.12 ETO12669.1 - 2.6e-08 33.9 0.8 5.6e-08 32.8 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Synapsin_C PF02750.9 ETO12670.1 - 7.4e-17 61.1 0.1 8.9e-17 60.8 0.1 1.1 1 0 0 1 1 1 1 Synapsin, ATP binding domain Vip3A_N PF12495.3 ETO12670.1 - 0.048 13.3 0.0 0.095 12.3 0.0 1.5 1 1 0 1 1 1 0 Vegetative insecticide protein 3A N terminal Synapsin_C PF02750.9 ETO12671.1 - 1.3e-19 70.1 0.1 1.9e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Synapsin, ATP binding domain Synapsin PF02078.11 ETO12671.1 - 8.9e-08 32.2 0.0 2e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Synapsin, N-terminal domain DUF2857 PF11198.3 ETO12672.1 - 0.053 13.0 0.2 0.77 9.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2857) Drf_GBD PF06371.8 ETO12672.1 - 0.37 10.1 3.3 0.33 10.3 0.1 2.4 3 0 0 3 3 3 0 Diaphanous GTPase-binding Domain WD40 PF00400.27 ETO12673.1 - 2.5e-67 220.5 38.1 3.1e-12 45.8 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO12673.1 - 8.8e-10 37.3 13.6 0.0012 17.0 0.1 6.2 2 1 2 5 5 5 4 Nucleoporin Nup120/160 HapK PF11639.3 ETO12673.1 - 0.099 13.2 1.3 10 6.8 0.2 3.0 2 1 0 2 2 2 0 REDY-like protein HapK DNA_Packaging_2 PF11123.3 ETO12673.1 - 0.23 11.3 3.4 1.2 9.0 0.3 2.4 2 0 0 2 2 2 0 DNA packaging protein zf-C4H2 PF10146.4 ETO12673.1 - 0.7 9.8 17.5 1 9.3 12.1 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein SprA-related PF12118.3 ETO12674.1 - 0.25 10.6 27.4 0.017 14.4 10.6 2.2 2 0 0 2 2 2 0 SprA-related family TPR_17 PF13431.1 ETO12675.1 - 3.8e-06 26.6 4.7 0.0021 18.1 0.4 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO12675.1 - 3.9e-06 26.4 7.9 0.0016 18.0 0.8 3.1 1 1 2 3 3 3 3 TPR repeat TPR_12 PF13424.1 ETO12675.1 - 0.00082 19.2 3.2 1 9.3 0.4 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO12675.1 - 0.00084 19.0 7.2 0.039 13.8 0.1 4.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO12675.1 - 0.0011 18.4 9.8 1 9.0 0.4 4.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO12675.1 - 0.0027 18.3 0.6 0.23 12.2 0.2 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO12675.1 - 0.0035 17.8 0.1 0.18 12.5 0.0 2.6 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO12675.1 - 0.0062 16.8 0.8 1.3 9.4 0.0 3.1 3 1 0 3 3 3 1 Tetratricopeptide repeat FAT PF02259.18 ETO12675.1 - 0.023 13.6 0.1 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 FAT domain TPR_8 PF13181.1 ETO12675.1 - 0.31 10.9 1.6 19 5.3 0.0 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat SAPS PF04499.10 ETO12676.1 - 1.5e-25 89.8 24.0 1.5e-22 79.9 0.5 3.3 2 1 1 3 3 3 2 SIT4 phosphatase-associated protein Mucin PF01456.12 ETO12676.1 - 2.8 7.7 15.6 6.8 6.4 10.8 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein Atrophin-1 PF03154.10 ETO12676.1 - 2.9 5.9 22.5 0.021 12.9 4.7 2.3 2 1 0 2 2 2 0 Atrophin-1 family DUF4587 PF15248.1 ETO12676.1 - 5.4 7.6 5.9 27 5.4 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4587) zf-TRAF PF02176.13 ETO12677.1 - 0.0022 18.3 2.1 0.0022 18.3 1.5 3.0 2 0 0 2 2 2 1 TRAF-type zinc finger GP41 PF00517.12 ETO12677.1 - 0.0063 16.1 12.2 0.15 11.5 0.9 2.7 1 1 0 2 2 2 2 Retroviral envelope protein Cleaved_Adhesin PF07675.6 ETO12678.1 - 0.13 11.8 3.7 0.14 11.7 1.3 1.9 2 0 0 2 2 2 0 Cleaved Adhesin Domain EF-hand_7 PF13499.1 ETO12679.1 - 1.4e-06 28.3 0.3 2.7e-06 27.3 0.2 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO12679.1 - 2.1e-06 26.6 0.1 0.0024 17.0 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 ETO12679.1 - 5.9e-06 25.8 1.1 0.011 15.3 0.1 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO12679.1 - 0.0017 18.0 0.2 0.63 10.0 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 ETO12679.1 - 0.023 14.7 1.8 0.043 13.8 1.3 1.6 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.1 ETO12679.1 - 0.056 12.8 0.3 2.8 7.4 0.0 2.7 2 1 0 2 2 2 0 EF hand DUF262 PF03235.9 ETO12679.1 - 0.13 12.2 2.8 0.15 12.0 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 DUF1635 PF07795.6 ETO12680.1 - 0.039 13.3 0.6 0.043 13.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DDE_1 PF03184.14 ETO12680.1 - 0.057 12.5 0.4 0.085 11.9 0.3 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF3492 PF11997.3 ETO12680.1 - 0.097 12.2 0.4 0.11 11.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) Cas_Cas6 PF01881.11 ETO12680.1 - 5.8 7.1 9.4 4.2 7.6 3.0 2.1 1 1 1 2 2 2 0 CRISPR associated protein Cas6 NST1 PF13945.1 ETO12681.1 - 2 8.4 9.2 1.5 8.8 5.5 1.4 1 1 0 1 1 1 0 Salt tolerance down-regulator BLVR PF06375.6 ETO12681.1 - 3.9 7.2 15.4 8.8 6.1 9.3 2.3 3 0 0 3 3 3 0 Bovine leukaemia virus receptor (BLVR) Mucin PF01456.12 ETO12682.1 - 0.054 13.2 11.8 0.091 12.5 8.2 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.3 ETO12682.1 - 0.14 11.9 9.6 0.28 10.9 6.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 ETO12682.1 - 3.1 5.4 4.9 3.7 5.1 3.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Innexin PF00876.13 ETO12684.1 - 0.012 14.7 0.5 0.017 14.2 0.4 1.2 1 0 0 1 1 1 0 Innexin SID-1_RNA_chan PF13965.1 ETO12684.1 - 0.029 12.5 0.5 0.037 12.2 0.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 ABC_membrane PF00664.18 ETO12684.1 - 0.044 13.1 0.3 0.054 12.8 0.2 1.1 1 0 0 1 1 1 0 ABC transporter transmembrane region YajC PF02699.10 ETO12684.1 - 0.15 11.7 2.8 0.36 10.5 1.9 1.7 1 1 0 1 1 1 0 Preprotein translocase subunit RCR PF12273.3 ETO12684.1 - 9.6 6.7 9.8 94 3.5 6.8 2.5 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF3477 PF11963.3 ETO12685.1 - 0.046 12.7 0.1 0.069 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3477) Serpin PF00079.15 ETO12686.1 - 4.5e-32 111.6 0.3 1.7e-27 96.5 0.5 3.0 2 1 0 2 2 2 2 Serpin (serine protease inhibitor) PH PF00169.24 ETO12686.1 - 0.0042 17.2 0.6 0.014 15.5 0.4 1.9 1 0 0 1 1 1 1 PH domain RRM_5 PF13893.1 ETO12687.1 - 1.3e-05 24.9 0.0 2.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO12687.1 - 0.00014 21.3 0.0 0.00035 20.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 ETO12688.1 - 5.8e-16 58.4 0.3 1.8e-11 43.6 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO12688.1 - 1.7e-05 24.0 0.0 0.013 14.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Daxx PF03344.10 ETO12689.1 - 0.01 14.3 30.2 0.014 13.9 20.9 1.3 1 0 0 1 1 1 0 Daxx Family ZZ PF00569.12 ETO12689.1 - 0.014 14.9 2.1 0.035 13.6 1.5 1.6 1 0 0 1 1 1 0 Zinc finger, ZZ type CDC45 PF02724.9 ETO12689.1 - 0.02 12.9 21.4 0.029 12.4 14.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 ETO12689.1 - 0.03 12.2 38.7 0.041 11.8 26.8 1.2 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 ETO12689.1 - 0.58 9.3 21.2 0.82 8.8 14.7 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Ycf1 PF05758.7 ETO12689.1 - 2.1 5.9 17.0 3.2 5.3 11.8 1.3 1 0 0 1 1 1 0 Ycf1 Paf1 PF03985.8 ETO12689.1 - 2.4 6.7 31.3 3.9 6.0 21.7 1.3 1 0 0 1 1 1 0 Paf1 SprA-related PF12118.3 ETO12689.1 - 3.6 6.8 19.0 5.6 6.1 13.2 1.3 1 0 0 1 1 1 0 SprA-related family WD40 PF00400.27 ETO12690.1 - 1.8e-156 503.1 55.4 4e-14 51.8 0.8 12.6 13 0 0 13 13 13 12 WD domain, G-beta repeat eIF2A PF08662.6 ETO12690.1 - 4.6e-20 72.1 0.1 0.00042 20.0 0.0 5.5 1 1 6 7 7 7 7 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO12690.1 - 3.5e-16 58.4 19.3 0.14 10.2 0.0 10.5 1 1 8 9 9 9 7 Nucleoporin Nup120/160 PD40 PF07676.7 ETO12690.1 - 2.5e-09 36.5 21.5 3.7 7.3 0.1 9.5 10 0 0 10 10 10 2 WD40-like Beta Propeller Repeat DUF3312 PF11768.3 ETO12690.1 - 0.0011 17.3 0.0 3.7 5.6 0.0 3.9 3 2 2 5 5 5 3 Protein of unknown function (DUF3312) Cytochrom_D1 PF02239.11 ETO12690.1 - 0.0021 16.4 12.5 0.12 10.6 0.3 5.3 1 1 4 6 6 6 2 Cytochrome D1 heme domain DHFR_2 PF06442.6 ETO12690.1 - 0.0022 17.5 0.0 37 4.0 0.0 5.2 5 1 1 6 6 6 0 R67 dihydrofolate reductase Methyltransf_10 PF05971.7 ETO12690.1 - 0.0041 16.3 0.0 6.8 5.7 0.0 4.7 4 2 2 6 6 6 1 Protein of unknown function (DUF890) DUF727 PF05303.7 ETO12690.1 - 0.0041 16.8 5.1 39 4.0 0.0 7.5 10 2 2 12 12 12 0 Protein of unknown function (DUF727) CNH PF00780.17 ETO12690.1 - 0.0065 15.9 0.0 52 3.1 0.0 5.8 8 1 1 9 9 9 0 CNH domain DUF3859 PF12975.2 ETO12690.1 - 0.018 14.6 0.1 0.082 12.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3859) Gmad1 PF10647.4 ETO12690.1 - 0.02 14.3 0.1 24 4.1 0.0 4.5 4 1 1 5 5 5 0 Lipoprotein LpqB beta-propeller domain DUF1258 PF06869.7 ETO12690.1 - 0.33 10.0 4.6 9.5 5.2 0.0 4.0 2 2 3 6 6 6 0 Protein of unknown function (DUF1258) CS PF04969.11 ETO12691.1 - 0.0029 18.1 0.2 0.0029 18.1 0.2 3.3 4 1 1 5 5 4 1 CS domain DUF4200 PF13863.1 ETO12691.1 - 0.056 13.3 34.9 0.038 13.9 12.2 3.2 2 2 0 2 2 2 0 Domain of unknown function (DUF4200) DUF3450 PF11932.3 ETO12691.1 - 0.27 10.4 13.4 0.31 10.2 4.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF550 PF04447.7 ETO12691.1 - 0.42 10.2 8.3 0.6 9.7 2.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF550) GAS PF13851.1 ETO12691.1 - 0.85 8.7 30.0 0.063 12.4 17.0 1.9 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1640 PF07798.6 ETO12691.1 - 0.92 9.5 17.7 4.3 7.3 10.1 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) SlyX PF04102.7 ETO12691.1 - 0.98 9.8 12.6 0.67 10.3 0.5 3.0 2 1 0 2 2 2 0 SlyX TMF_DNA_bd PF12329.3 ETO12691.1 - 4.2 7.2 33.8 0.44 10.3 3.0 3.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.16 ETO12691.1 - 6.7 6.7 16.6 0.98 9.4 1.2 3.6 3 1 0 3 3 3 0 bZIP transcription factor V_ATPase_I PF01496.14 ETO12691.1 - 7.5 4.2 20.5 10 3.8 14.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-C4H2 PF10146.4 ETO12691.1 - 7.6 6.4 20.3 0.85 9.5 7.9 2.6 1 1 1 2 2 2 0 Zinc finger-containing protein DUF4391 PF14335.1 ETO12692.1 - 0.75 9.1 12.8 0.49 9.7 7.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4391) AA_permease_N PF08403.5 ETO12693.1 - 0.047 13.0 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 Amino acid permease N-terminal GBP PF02263.14 ETO12694.1 - 4e-07 29.3 0.2 2.4e-05 23.5 0.0 2.1 1 1 1 2 2 2 1 Guanylate-binding protein, N-terminal domain RHD3 PF05879.7 ETO12694.1 - 8.9e-06 23.9 0.1 1.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.18 ETO12694.1 - 0.00022 21.1 0.0 0.00033 20.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 ETO12694.1 - 0.0004 20.2 0.0 0.00065 19.5 0.0 1.6 1 1 0 1 1 1 1 Dynamin family AAA_16 PF13191.1 ETO12694.1 - 0.0036 17.3 0.1 0.0068 16.4 0.0 1.5 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 ETO12694.1 - 0.0047 17.4 0.0 0.0081 16.6 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein AAA_18 PF13238.1 ETO12694.1 - 0.0066 16.7 0.4 0.066 13.5 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO12694.1 - 0.0089 16.8 0.1 0.025 15.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.1 ETO12694.1 - 0.012 15.6 2.0 0.043 13.7 1.4 1.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 ETO12694.1 - 0.014 15.3 0.1 0.036 14.0 0.1 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 ETO12694.1 - 0.022 15.0 0.1 0.032 14.5 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 ETO12694.1 - 0.031 14.1 0.0 0.064 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 ETO12694.1 - 0.065 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 ETO12694.1 - 0.078 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DAP3 PF10236.4 ETO12694.1 - 0.084 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 5_nucleotid PF05761.9 ETO12695.1 - 0.001 17.6 0.0 0.0015 17.0 0.0 1.2 1 0 0 1 1 1 1 5' nucleotidase family zf-PARP PF00645.13 ETO12696.1 - 2.9e-10 40.2 3.4 2.9e-10 40.2 2.3 2.3 2 2 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region SAP PF02037.22 ETO12696.1 - 2e-09 36.7 0.0 5.3e-09 35.3 0.0 1.8 1 0 0 1 1 1 1 SAP domain SAP30_Sin3_bdg PF13867.1 ETO12696.1 - 0.0095 15.7 0.1 0.027 14.3 0.0 1.8 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Carboxyl_trans PF01039.17 ETO12696.1 - 1.2 7.3 4.3 1.8 6.8 3.0 1.2 1 0 0 1 1 1 0 Carboxyl transferase domain CRT10 PF08728.5 ETO12696.1 - 3.9 5.3 9.8 3.4 5.5 6.8 1.1 1 0 0 1 1 1 0 CRT10 MIP-T3 PF10243.4 ETO12698.1 - 0.59 8.5 54.1 0.81 8.0 37.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Utp14 PF04615.8 ETO12698.1 - 5.4 5.0 49.1 7.4 4.6 34.1 1.0 1 0 0 1 1 1 0 Utp14 protein DUF4389 PF14333.1 ETO12699.1 - 0.07 12.8 0.0 0.2 11.3 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4389) SAM_1 PF00536.25 ETO12699.1 - 0.13 12.5 0.5 2.5 8.3 0.1 2.2 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) WD40 PF00400.27 ETO12701.1 - 0.058 13.2 0.1 1.4 8.9 0.0 2.8 1 1 1 2 2 2 0 WD domain, G-beta repeat WD40 PF00400.27 ETO12702.1 - 1.1e-28 98.0 10.2 1.4e-11 43.7 0.3 4.4 4 1 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO12702.1 - 8e-05 20.9 0.6 0.22 9.6 0.1 2.8 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO12702.1 - 4.6 7.5 5.7 92 3.4 0.1 3.8 3 1 1 4 4 4 0 Kelch motif Thioredoxin_2 PF13098.1 ETO12703.1 - 0.036 14.2 0.4 0.039 14.1 0.3 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain BAH PF01426.13 ETO12703.1 - 0.078 12.7 0.2 0.085 12.6 0.1 1.2 1 0 0 1 1 1 0 BAH domain ubiquitin PF00240.18 ETO12704.1 - 1.7e-30 104.2 13.6 1.8e-14 52.8 0.9 3.2 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.3 ETO12704.1 - 1.8e-13 49.9 8.1 6.6e-06 25.7 0.5 3.1 2 1 1 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 ETO12704.1 - 0.098 12.9 1.8 0.37 11.0 0.0 2.5 3 0 0 3 3 3 0 Ubiquitin-like domain Gon7 PF08738.5 ETO12705.1 - 0.35 10.8 1.8 0.43 10.6 0.3 1.8 2 0 0 2 2 2 0 Gon7 family Wzy_C PF04932.10 ETO12707.1 - 0.0061 16.3 0.9 0.0083 15.9 0.6 1.2 1 0 0 1 1 1 1 O-Antigen ligase Ebola_NP PF05505.7 ETO12708.1 - 9.2 4.1 10.7 12 3.8 7.4 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein TFIIS_M PF07500.9 ETO12709.1 - 2.2e-12 47.0 6.6 2.2e-12 47.0 4.6 3.0 2 1 1 3 3 3 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 ETO12709.1 - 0.014 15.8 0.0 0.058 13.8 0.0 2.1 1 1 0 1 1 1 0 SPOC domain DUF2795 PF11387.3 ETO12709.1 - 0.047 13.5 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2795) Cupin_8 PF13621.1 ETO12710.1 - 9.3e-08 31.8 4.5 1.7e-07 31.0 3.2 1.3 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 ETO12710.1 - 2.6e-06 27.6 3.3 2.8e-06 27.5 0.1 2.6 3 0 0 3 3 3 1 JmjC domain, hydroxylase NodZ PF05830.6 ETO12711.1 - 0.09 11.3 0.4 0.18 10.3 0.3 1.5 1 1 0 1 1 1 0 Nodulation protein Z (NodZ) WD40 PF00400.27 ETO12712.1 - 1.8e-10 40.2 0.7 7.7e-09 35.1 0.1 2.5 2 1 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO12712.1 - 0.077 11.1 0.0 0.077 11.1 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 BTV_NS2 PF04514.7 ETO12713.1 - 0.21 10.4 21.5 0.25 10.2 14.9 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Ctr PF04145.10 ETO12713.1 - 0.37 10.8 8.8 0.26 11.3 1.6 2.2 2 0 0 2 2 2 0 Ctr copper transporter family eIF3_subunit PF08597.5 ETO12713.1 - 0.95 8.9 32.0 0.22 11.0 10.3 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Mitofilin PF09731.4 ETO12713.1 - 1.2 7.6 24.7 1.6 7.2 17.1 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MAT1 PF06391.8 ETO12713.1 - 2.9 7.4 29.7 0.33 10.5 11.7 2.1 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 PGA2 PF07543.7 ETO12713.1 - 3.5 7.4 27.1 0.26 11.0 13.0 2.3 1 1 1 2 2 2 0 Protein trafficking PGA2 Topoisom_I_N PF02919.10 ETO12713.1 - 4.8 6.4 14.8 5.2 6.2 2.5 2.3 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment DUF1168 PF06658.7 ETO12713.1 - 6.4 6.2 35.3 0.77 9.2 11.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) DUF2254 PF10011.4 ETO12713.1 - 9.7 4.5 6.8 21 3.4 4.7 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) MerR-DNA-bind PF09278.6 ETO12714.1 - 0.059 13.7 0.3 0.059 13.7 0.2 2.4 3 0 0 3 3 3 0 MerR, DNA binding DUF972 PF06156.8 ETO12714.1 - 0.32 11.3 13.2 1.2 9.5 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) FTCD_C PF04961.7 ETO12714.1 - 0.91 8.9 8.8 2 7.8 1.7 2.1 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase Spectrin PF00435.16 ETO12714.1 - 0.92 9.8 9.5 1.5 9.1 1.1 2.3 2 0 0 2 2 2 0 Spectrin repeat COG2 PF06148.6 ETO12714.1 - 5 7.0 8.3 1.9 8.3 0.6 2.5 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4463 PF14703.1 ETO12714.1 - 5.2 7.6 9.2 0.5 10.9 1.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4463) Retrotrans_gag PF03732.12 ETO12714.1 - 6.5 6.8 11.2 0.3 11.1 2.4 2.4 2 2 0 2 2 2 0 Retrotransposon gag protein CDC45 PF02724.9 ETO12715.1 - 8.2 4.3 10.3 12 3.8 7.2 1.2 1 0 0 1 1 1 0 CDC45-like protein SAC3_GANP PF03399.11 ETO12717.1 - 8e-13 48.4 3.9 8e-13 48.4 2.7 2.2 2 1 0 2 2 2 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Ribonuc_P_40 PF08584.6 ETO12717.1 - 0.043 12.8 0.1 0.08 11.9 0.1 1.3 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit Sigma70_ner PF04546.8 ETO12718.1 - 0.1 12.1 2.7 0.22 11.0 1.9 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.7 ETO12718.1 - 0.11 11.7 4.7 0.17 11.1 3.2 1.3 1 0 0 1 1 1 0 NOA36 protein Nucleo_P87 PF07267.6 ETO12718.1 - 0.12 11.0 7.0 0.18 10.4 4.8 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Nucleoplasmin PF03066.10 ETO12718.1 - 0.13 11.7 3.3 0.26 10.7 2.3 1.5 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 ETO12718.1 - 0.18 11.6 4.4 0.54 10.0 3.1 1.8 1 0 0 1 1 1 0 RXT2-like, N-terminal PBP1_TM PF14812.1 ETO12718.1 - 1.3 9.3 11.5 0.23 11.7 4.1 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tom22 PF04281.8 ETO12718.1 - 5.6 6.4 7.7 0.92 9.0 2.1 2.2 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Spt20 PF12090.3 ETO12719.1 - 2.3 7.5 10.3 11 5.3 5.8 2.3 2 0 0 2 2 2 0 Spt20 family DUF3439 PF11921.3 ETO12720.1 - 0.063 13.0 1.9 0.09 12.5 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF2992 PF11208.3 ETO12720.1 - 0.25 11.2 8.8 0.41 10.5 6.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Utp14 PF04615.8 ETO12720.1 - 2.1 6.3 26.3 2.5 6.1 18.2 1.1 1 0 0 1 1 1 0 Utp14 protein Lin-8 PF03353.10 ETO12720.1 - 3.8 6.6 15.4 4 6.6 10.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Mitofilin PF09731.4 ETO12720.1 - 5 5.6 15.2 5.4 5.5 10.5 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein WD40 PF00400.27 ETO12721.1 - 1.9e-09 37.0 0.0 2.7e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Acyltransferase PF01553.16 ETO12722.1 - 1.3e-08 34.3 0.0 2.7e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase TM_helix PF05552.7 ETO12722.1 - 0.14 11.8 0.7 0.28 10.8 0.5 1.4 1 0 0 1 1 1 0 Conserved TM helix 2-oxoacid_dh PF00198.18 ETO12723.1 - 1.5e-78 263.2 0.0 2.3e-78 262.6 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.12 ETO12723.1 - 6.7e-11 41.6 0.0 1.3e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl PF00364.17 ETO12723.1 - 0.00036 20.1 0.1 0.097 12.3 0.0 3.2 3 1 0 3 3 3 1 Biotin-requiring enzyme ORC6 PF05460.8 ETO12723.1 - 0.0014 17.8 1.7 0.0022 17.1 1.2 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Ribosomal_60s PF00428.14 ETO12725.1 - 0.027 14.8 3.1 0.027 14.8 2.1 5.2 4 2 1 5 5 5 0 60s Acidic ribosomal protein DUF2524 PF10732.4 ETO12727.1 - 0.025 14.6 0.8 0.074 13.1 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) DUF2185 PF09951.4 ETO12727.1 - 0.079 12.7 0.5 0.25 11.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2185) DUF1015 PF06245.6 ETO12728.1 - 2.8e-124 414.7 0.0 1.4e-123 412.4 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1015) DUF262 PF03235.9 ETO12728.1 - 0.15 11.9 2.2 0.63 9.9 0.1 2.3 1 1 0 2 2 2 0 Protein of unknown function DUF262 G-gamma PF00631.17 ETO12730.1 - 0.0068 16.1 0.9 0.024 14.3 0.7 2.0 1 0 0 1 1 1 1 GGL domain Kinase-PPPase PF03618.9 ETO12730.1 - 0.01 15.3 0.0 0.029 13.8 0.0 1.7 1 0 0 1 1 1 0 Kinase/pyrophosphorylase DUF2370 PF10176.4 ETO12730.1 - 0.57 9.4 2.9 0.93 8.7 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Kelch_5 PF13854.1 ETO12731.1 - 2.6e-06 27.2 1.9 3 7.9 0.0 5.4 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO12731.1 - 3.9e-06 26.5 0.5 0.71 9.6 0.0 4.6 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO12731.1 - 2.3e-05 24.4 1.4 0.29 11.3 0.0 4.3 3 1 0 3 3 3 2 Galactose oxidase, central domain Secretin_N_2 PF07655.8 ETO12731.1 - 0.78 10.1 6.5 2.3 8.6 4.5 1.7 1 0 0 1 1 1 0 Secretin N-terminal domain Kelch_2 PF07646.10 ETO12731.1 - 1.1 9.1 9.7 4.8 7.1 0.1 5.2 8 0 0 8 8 8 0 Kelch motif Kelch_1 PF01344.20 ETO12731.1 - 5.7 6.5 7.9 34 4.0 0.5 4.4 4 1 0 4 4 4 0 Kelch motif WD40 PF00400.27 ETO12732.1 - 1.3e-81 265.7 11.2 1.1e-14 53.6 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO12732.1 - 7.3e-17 61.7 0.0 1.3e-06 28.2 0.0 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO12732.1 - 4.5e-10 38.9 6.4 2.9 7.6 0.1 7.0 7 0 0 7 7 7 3 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO12732.1 - 6.9e-06 24.4 2.0 2.1 6.3 0.0 4.6 1 1 3 5 5 5 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO12732.1 - 3.2e-05 22.4 0.3 0.0044 15.3 0.0 2.9 1 1 2 3 3 3 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO12732.1 - 0.00025 19.9 4.2 0.054 12.2 0.1 4.2 1 1 3 5 5 5 1 Nup133 N terminal like Surfac_D-trimer PF09006.6 ETO12732.1 - 0.00027 20.5 0.1 20 5.0 0.0 5.3 6 0 0 6 6 6 0 Lung surfactant protein D coiled-coil trimerisation Gmad1 PF10647.4 ETO12732.1 - 0.00058 19.3 0.0 0.5 9.7 0.0 3.0 2 1 1 3 3 3 1 Lipoprotein LpqB beta-propeller domain Nbas_N PF15492.1 ETO12732.1 - 0.00058 19.0 1.0 7 5.6 0.0 4.7 1 1 4 5 5 5 1 Neuroblastoma-amplified sequence, N terminal DPPIV_N PF00930.16 ETO12732.1 - 0.0015 17.1 0.1 5.8 5.3 0.0 4.7 1 1 3 5 5 5 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Resistin PF06954.6 ETO12732.1 - 0.0021 18.3 0.1 20 5.5 0.0 5.2 1 1 6 7 7 7 0 Resistin PQQ_2 PF13360.1 ETO12732.1 - 0.0068 15.8 0.0 0.027 13.9 0.0 1.9 1 1 0 1 1 1 1 PQQ-like domain Str_synth PF03088.11 ETO12732.1 - 0.0098 15.9 0.0 12 5.9 0.0 3.5 3 1 1 4 4 4 0 Strictosidine synthase PLD_C PF12357.3 ETO12732.1 - 0.041 13.4 0.1 37 3.9 0.0 3.7 4 1 0 4 4 4 0 Phospholipase D C terminal Proteasome_A_N PF10584.4 ETO12732.1 - 0.061 12.6 16.2 3 7.2 0.0 6.2 6 1 1 7 7 7 0 Proteasome subunit A N-terminal signature TPR_12 PF13424.1 ETO12733.1 - 4.6e-31 106.5 8.3 5e-12 45.5 0.7 3.2 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO12733.1 - 4.6e-17 61.4 9.6 4.6e-09 35.8 1.8 3.6 1 1 1 3 3 3 3 TPR repeat TPR_7 PF13176.1 ETO12733.1 - 4e-15 54.3 1.0 0.00035 20.1 0.1 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO12733.1 - 1.6e-14 52.5 6.1 0.00028 20.5 0.1 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO12733.1 - 3.6e-14 51.6 12.8 4.6e-07 29.1 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO12733.1 - 1.3e-13 49.6 13.1 3.7e-05 23.1 0.2 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO12733.1 - 2.7e-13 49.3 0.0 9.5e-05 22.1 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO12733.1 - 2.8e-05 24.6 0.0 0.13 12.9 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO12733.1 - 0.00015 22.0 0.0 0.33 11.7 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO12733.1 - 0.0002 21.3 6.5 0.025 14.7 0.3 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO12733.1 - 0.00024 21.3 1.3 13 6.5 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 ETO12733.1 - 0.0008 19.4 9.0 0.37 10.9 1.4 3.3 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 ETO12733.1 - 0.0014 18.4 2.2 15 5.7 0.0 4.8 5 0 0 5 5 5 0 PPR repeat DUF2225 PF09986.4 ETO12733.1 - 0.004 16.6 3.0 0.01 15.2 1.3 2.4 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.13 ETO12733.1 - 0.024 14.5 4.2 61 3.6 0.0 4.4 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.1 ETO12733.1 - 0.029 14.7 0.1 1.2 9.4 0.0 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat DUF2629 PF10945.3 ETO12733.1 - 0.051 12.9 0.1 0.12 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2629) Caldesmon PF02029.10 ETO12733.1 - 0.32 9.3 5.5 0.38 9.1 0.4 2.4 3 0 0 3 3 3 0 Caldesmon Sel1 PF08238.7 ETO12733.1 - 0.33 11.6 2.6 31 5.3 0.0 4.1 4 0 0 4 4 4 0 Sel1 repeat WD40 PF00400.27 ETO12734.1 - 4.7e-32 108.7 14.3 7.2e-10 38.3 0.1 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO12734.1 - 4.2e-06 25.1 3.1 0.031 12.4 0.0 3.0 2 1 1 3 3 3 3 Nucleoporin Nup120/160 DUF851 PF05867.6 ETO12734.1 - 0.028 13.6 0.0 0.05 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF851) UEV PF05743.8 ETO12735.1 - 1.7e-33 114.9 0.1 3e-33 114.0 0.1 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 ETO12735.1 - 5.6e-17 61.1 0.3 1.2e-16 60.0 0.2 1.6 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.21 ETO12735.1 - 8.9e-06 25.1 0.5 1.9e-05 24.1 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF4407 PF14362.1 ETO12735.1 - 7.3 5.4 10.9 27 3.5 7.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) YhjQ PF06564.7 ETO12737.1 - 0.00036 19.9 0.2 0.069 12.4 0.1 2.2 2 0 0 2 2 2 2 YhjQ protein Zip PF02535.17 ETO12737.1 - 8.6 5.2 8.2 1.4 7.8 0.5 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Metallophos_C PF14008.1 ETO12738.1 - 0.024 14.7 0.2 0.057 13.5 0.1 1.8 1 1 0 1 1 1 0 Iron/zinc purple acid phosphatase-like protein C Exo_endo_phos PF03372.18 ETO12739.1 - 8.1e-06 25.9 0.0 1.3e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF769 PF05590.6 ETO12740.1 - 0.071 12.3 1.0 0.08 12.1 0.7 1.0 1 0 0 1 1 1 0 Xylella fastidiosa protein of unknown function (DUF769) DUSP PF06337.7 ETO12740.1 - 0.3 11.5 4.2 1.1 9.7 2.9 1.8 1 1 0 1 1 1 0 DUSP domain ART PF01129.13 ETO12741.1 - 0.0001 21.4 0.0 0.00019 20.6 0.0 1.4 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase TUG-UBL1 PF11470.3 ETO12741.1 - 0.024 14.5 1.4 0.051 13.5 0.3 2.0 2 0 0 2 2 2 0 GLUT4 regulating protein TUG PH PF00169.24 ETO12742.1 - 8e-08 32.4 2.5 0.00027 21.1 0.1 3.2 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 ETO12742.1 - 0.0004 20.6 11.2 0.00093 19.4 0.1 4.4 3 3 0 3 3 3 2 Pleckstrin homology domain WD40 PF00400.27 ETO12743.1 - 3.3e-09 36.2 0.1 7.9e-09 35.0 0.0 1.7 2 0 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO12743.1 - 0.00063 18.0 0.0 0.00063 18.0 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 EBA-175_VI PF11556.3 ETO12744.1 - 0.018 15.1 0.4 0.018 15.1 0.3 1.6 2 0 0 2 2 2 0 Erythrocyte binding antigen 175 PBP1_TM PF14812.1 ETO12744.1 - 0.12 12.7 7.8 0.21 11.8 0.3 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2413 PF10310.4 ETO12744.1 - 0.51 9.1 4.4 1.3 7.7 2.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2413) Myc_N PF01056.13 ETO12744.1 - 0.7 9.0 3.7 0.98 8.5 2.5 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF1510 PF07423.6 ETO12744.1 - 1.4 8.2 9.3 3.3 7.0 6.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4604 PF15377.1 ETO12744.1 - 1.4 9.0 11.9 0.62 10.2 3.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) RRP7 PF12923.2 ETO12744.1 - 1.5 8.8 9.4 7.2 6.6 2.4 2.0 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) Roughex PF06020.6 ETO12745.1 - 0.1 11.2 0.2 0.13 10.9 0.1 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF2884 PF11101.3 ETO12746.1 - 0.024 14.0 10.1 0.028 13.8 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) UPF0193 PF05250.6 ETO12746.1 - 0.033 13.7 7.0 0.037 13.6 4.8 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0193) Peptidase_C5 PF00770.13 ETO12746.1 - 0.056 12.9 0.3 0.078 12.5 0.2 1.2 1 0 0 1 1 1 0 Adenovirus endoprotease CENP-R PF06729.7 ETO12746.1 - 0.11 12.1 3.5 0.11 12.1 2.0 1.3 1 1 0 1 1 1 0 Kinetochore component, CENP-R DUF651 PF04895.7 ETO12746.1 - 0.18 11.4 4.9 0.22 11.1 0.3 2.0 1 1 1 2 2 2 0 Archaeal protein of unknown function (DUF651) DUF4349 PF14257.1 ETO12746.1 - 0.26 10.4 5.0 0.26 10.4 3.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) I_LWEQ PF01608.12 ETO12746.1 - 1.4 8.8 6.7 1.6 8.6 4.6 1.1 1 0 0 1 1 1 0 I/LWEQ domain DUF883 PF05957.8 ETO12746.1 - 2 8.8 6.5 5.8 7.3 0.7 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Prefoldin_2 PF01920.15 ETO12746.1 - 3.6 7.4 14.2 1.2 8.8 3.3 2.1 2 0 0 2 2 2 0 Prefoldin subunit Viral_P18 PF04521.8 ETO12746.1 - 8.1 5.9 9.0 2.6 7.5 1.9 2.0 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein V_ATPase_I PF01496.14 ETO12747.1 - 0.09 10.6 9.0 0.095 10.5 6.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Zn_protease PF05618.6 ETO12747.1 - 0.13 11.9 0.1 0.13 11.9 0.0 2.1 2 1 1 3 3 3 0 Putative ATP-dependant zinc protease DUF1636 PF07845.6 ETO12747.1 - 0.36 11.0 3.7 0.26 11.5 0.7 2.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1636) IncA PF04156.9 ETO12747.1 - 2.5 7.6 21.5 1.9 8.0 13.8 1.6 1 1 0 1 1 1 0 IncA protein G-alpha PF00503.15 ETO12749.1 - 8.6e-20 70.7 18.3 2.3e-19 69.3 12.7 1.8 1 1 0 1 1 1 1 G-protein alpha subunit AAA_17 PF13207.1 ETO12749.1 - 0.00043 21.0 1.6 0.0014 19.4 1.1 1.9 1 1 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 ETO12749.1 - 0.00059 19.7 1.2 0.00093 19.0 0.9 1.4 1 0 0 1 1 1 1 Dynamin family AAA_21 PF13304.1 ETO12749.1 - 0.00091 19.2 2.2 0.0012 18.8 1.5 1.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 ETO12749.1 - 0.002 17.5 0.0 0.0036 16.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain PRK PF00485.13 ETO12749.1 - 0.0031 17.1 2.2 0.01 15.4 1.5 1.9 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family MCM PF00493.18 ETO12749.1 - 0.034 12.9 0.1 0.034 12.9 0.1 2.4 1 1 1 2 2 2 0 MCM2/3/5 family Arf PF00025.16 ETO12749.1 - 0.061 12.5 0.0 0.061 12.5 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family Dsh_C PF12316.3 ETO12749.1 - 0.063 13.3 1.1 0.11 12.6 0.7 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal GAGA_bind PF06217.7 ETO12749.1 - 0.068 13.1 11.1 0.08 12.8 7.7 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family AAA_5 PF07728.9 ETO12749.1 - 0.078 12.7 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) LicD PF04991.8 ETO12749.1 - 0.11 12.5 7.3 0.18 11.8 5.1 1.4 1 0 0 1 1 1 0 LicD family Ycf1 PF05758.7 ETO12749.1 - 0.12 10.0 14.4 0.14 9.8 10.0 1.2 1 0 0 1 1 1 0 Ycf1 Neur_chan_memb PF02932.11 ETO12749.1 - 0.26 11.1 6.1 0.36 10.6 4.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ABC_tran PF00005.22 ETO12749.1 - 0.57 10.4 13.5 2.4 8.4 9.4 2.0 1 1 0 1 1 1 0 ABC transporter GPCR_chapero_1 PF11904.3 ETO12749.1 - 0.61 9.1 12.7 0.8 8.7 8.8 1.1 1 0 0 1 1 1 0 GPCR-chaperone Hid1 PF12722.2 ETO12749.1 - 1.1 6.7 12.4 1.4 6.4 8.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Mem_trans PF03547.13 ETO12749.1 - 1.5 7.0 3.0 1.7 6.8 2.1 1.1 1 0 0 1 1 1 0 Membrane transport protein AAA_23 PF13476.1 ETO12749.1 - 1.5 9.0 28.0 3.2 8.0 19.4 1.7 1 1 0 1 1 1 0 AAA domain DUF1510 PF07423.6 ETO12749.1 - 1.6 8.0 25.0 2.4 7.4 17.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Zip PF02535.17 ETO12749.1 - 1.6 7.6 4.7 2.1 7.2 3.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.9 ETO12749.1 - 1.7 6.5 22.3 2.3 6.1 15.4 1.1 1 0 0 1 1 1 0 CDC45-like protein TEX19 PF15553.1 ETO12749.1 - 2.6 7.8 9.8 4.1 7.2 6.8 1.3 1 0 0 1 1 1 0 Testis-expressed protein 19 Nop53 PF07767.6 ETO12749.1 - 2.9 6.8 31.4 4.8 6.0 21.7 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DDHD PF02862.12 ETO12749.1 - 3.4 7.4 10.5 6 6.5 7.2 1.5 1 0 0 1 1 1 0 DDHD domain MIP-T3 PF10243.4 ETO12749.1 - 3.7 5.8 30.1 6 5.2 20.9 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 BTV_NS2 PF04514.7 ETO12749.1 - 3.9 6.2 18.9 5.4 5.7 13.1 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Miro PF08477.8 ETO12749.1 - 6.1 7.3 8.9 0.63 10.5 0.1 2.5 1 1 1 2 2 2 0 Miro-like protein DUF4407 PF14362.1 ETO12749.1 - 9.8 5.0 8.1 18 4.1 5.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1510 PF07423.6 ETO12750.1 - 0.00042 19.7 1.0 0.0005 19.5 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Peptidase_S49_N PF08496.5 ETO12750.1 - 0.0022 17.8 4.9 0.0025 17.6 3.4 1.1 1 0 0 1 1 1 1 Peptidase family S49 N-terminal DUF2681 PF10883.3 ETO12750.1 - 0.0048 17.0 1.5 0.0067 16.6 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2681) DUF4446 PF14584.1 ETO12750.1 - 0.01 15.6 0.6 0.012 15.4 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) FAM176 PF14851.1 ETO12750.1 - 0.012 15.2 0.7 0.013 15.2 0.5 1.1 1 0 0 1 1 1 0 FAM176 family TMEM190 PF15431.1 ETO12750.1 - 0.014 15.2 0.2 0.018 14.9 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 190 TRAP_alpha PF03896.11 ETO12750.1 - 0.035 13.0 0.5 0.039 12.9 0.4 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit TMEM51 PF15345.1 ETO12750.1 - 0.056 13.1 0.3 0.064 12.9 0.2 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Endonuc_Holl PF10107.4 ETO12750.1 - 0.079 12.6 1.9 0.1 12.3 1.3 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase MLANA PF14991.1 ETO12750.1 - 0.084 12.8 0.1 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein melan-A Phage_CRI PF05144.9 ETO12750.1 - 0.087 11.9 1.7 0.11 11.5 1.2 1.2 1 0 0 1 1 1 0 Phage replication protein CRI DUF2215 PF10225.4 ETO12750.1 - 0.13 11.7 0.2 0.14 11.5 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Nucleoside_tran PF01733.13 ETO12750.1 - 0.18 10.9 0.6 0.19 10.8 0.4 1.1 1 0 0 1 1 1 0 Nucleoside transporter DUF972 PF06156.8 ETO12750.1 - 0.81 10.0 6.5 1 9.7 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) WD40 PF00400.27 ETO12752.1 - 1.2e-30 104.2 15.7 3.4e-09 36.2 0.0 5.2 4 1 1 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO12752.1 - 0.0067 14.6 0.1 1.3 7.0 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 SseC PF04888.7 ETO12752.1 - 0.069 12.4 5.3 0.089 12.1 3.7 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Atg14 PF10186.4 ETO12752.1 - 0.32 9.9 10.3 0.51 9.2 7.1 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4200 PF13863.1 ETO12752.1 - 3.7 7.5 23.3 0.043 13.7 10.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Cut12 PF11500.3 ETO12752.1 - 5.7 6.6 12.3 3.9 7.1 7.3 1.5 1 1 0 1 1 1 0 Spindle pole body formation-associated protein Med3 PF11593.3 ETO12754.1 - 0.035 13.3 6.2 0.043 13.0 4.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SR-25 PF10500.4 ETO12754.1 - 0.38 10.2 8.6 0.59 9.5 5.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.20 ETO12755.1 - 1.6e-22 79.8 0.0 7e-18 64.7 0.0 3.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO12755.1 - 1.1e-20 73.8 0.0 6.5e-15 54.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 ETO12755.1 - 0.023 13.7 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cluap1 PF10234.4 ETO12756.1 - 0.042 13.0 5.9 0.025 13.7 2.5 1.7 2 0 0 2 2 2 0 Clusterin-associated protein-1 Mnd1 PF03962.10 ETO12756.1 - 0.25 10.9 5.3 0.5 10.0 3.7 1.4 1 0 0 1 1 1 0 Mnd1 family RelB PF04221.7 ETO12757.1 - 0.044 13.5 0.0 0.09 12.5 0.0 1.5 1 0 0 1 1 1 0 RelB antitoxin Kelch_6 PF13964.1 ETO12759.1 - 3.9e-05 23.6 0.0 0.0037 17.3 0.0 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.20 ETO12759.1 - 7.5e-05 22.1 1.2 0.0028 17.1 0.1 2.6 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETO12759.1 - 0.00081 19.1 0.0 0.11 12.2 0.0 2.5 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO12759.1 - 0.02 15.0 0.1 0.1 12.8 0.0 2.1 2 1 0 2 2 2 0 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO12759.1 - 0.039 13.7 2.3 0.22 11.3 0.5 2.9 3 1 0 3 3 3 0 Kelch motif Kelch_5 PF13854.1 ETO12759.1 - 0.15 12.0 1.7 0.2 11.6 0.1 2.1 2 0 0 2 2 2 0 Kelch motif CPSase_L_D3 PF02787.14 ETO12760.1 - 0.013 15.2 2.6 0.024 14.4 1.6 1.5 1 1 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP11 PF06644.6 ETO12760.1 - 0.023 14.2 4.6 0.033 13.7 3.2 1.2 1 0 0 1 1 1 0 ATP11 protein S-methyl_trans PF02574.11 ETO12761.1 - 0.1 11.8 0.1 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Homocysteine S-methyltransferase Bul1_C PF04426.7 ETO12761.1 - 0.72 9.0 7.6 0.15 11.2 3.1 1.4 2 0 0 2 2 2 0 Bul1 C terminus DUF3795 PF12675.2 ETO12761.1 - 1.1 9.5 5.1 2.9 8.1 3.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) ubiquitin PF00240.18 ETO12762.1 - 5.9e-12 44.8 9.1 1.1e-10 40.7 0.7 2.5 3 0 0 3 3 3 2 Ubiquitin family Rad60-SLD PF11976.3 ETO12762.1 - 1.4e-06 27.8 2.6 3.6e-05 23.3 1.8 2.4 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 ETO12762.1 - 0.00044 20.3 2.2 0.00075 19.6 1.5 1.5 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 ETO12762.1 - 0.0055 16.5 2.0 0.013 15.4 1.3 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Pyr_redox_2 PF07992.9 ETO12763.1 - 7.1e-10 39.0 0.2 9.8e-05 22.3 0.0 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETO12763.1 - 3.1e-08 33.8 0.1 0.0024 18.2 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Melibiase PF02065.13 ETO12765.1 - 3.6e-07 29.2 2.2 1.1e-06 27.6 1.5 1.8 1 1 0 1 1 1 1 Melibiase CAP_GLY PF01302.20 ETO12767.1 - 1.4e-08 34.2 0.0 2.6e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF1510 PF07423.6 ETO12767.1 - 0.056 12.8 26.7 0.053 12.8 6.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) SID-1_RNA_chan PF13965.1 ETO12767.1 - 7.7 4.5 8.0 0.29 9.2 0.2 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Pkinase PF00069.20 ETO12769.1 - 2.5e-19 69.4 2.6 3.7e-14 52.5 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO12769.1 - 1.6e-05 24.1 0.5 0.0096 15.0 0.0 3.2 3 0 0 3 3 3 1 Protein tyrosine kinase Macoilin PF09726.4 ETO12769.1 - 0.00021 19.7 10.4 0.00028 19.3 7.2 1.1 1 0 0 1 1 1 1 Transmembrane protein Mucin PF01456.12 ETO12769.1 - 0.0065 16.2 29.1 0.011 15.5 20.2 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein Zip PF02535.17 ETO12769.1 - 0.29 10.1 10.5 0.41 9.6 7.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter MMR1 PF08505.5 ETO12769.1 - 0.77 9.7 18.5 1.3 8.9 12.8 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein TFIIA PF03153.8 ETO12769.1 - 1.3 8.8 12.8 1.8 8.3 8.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit G-alpha PF00503.15 ETO12770.1 - 2.7e-30 105.3 0.4 3.6e-30 104.9 0.3 1.1 1 0 0 1 1 1 1 G-protein alpha subunit ABC_tran PF00005.22 ETO12770.1 - 0.0032 17.7 0.0 0.0047 17.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_33 PF13671.1 ETO12770.1 - 0.0033 17.2 0.0 0.0052 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 ETO12770.1 - 0.0043 16.5 0.1 0.0081 15.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Miro PF08477.8 ETO12770.1 - 0.013 15.9 0.0 0.023 15.2 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein FtsK_SpoIIIE PF01580.13 ETO12770.1 - 0.027 13.9 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_28 PF13521.1 ETO12770.1 - 0.03 14.2 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 ETO12770.1 - 0.045 13.4 0.1 0.14 11.7 0.1 1.9 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.1 ETO12770.1 - 0.072 13.9 0.0 0.16 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain F_actin_bind PF08919.5 ETO12770.1 - 0.075 12.7 0.1 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 F-actin binding Viral_helicase1 PF01443.13 ETO12770.1 - 0.083 12.3 0.1 0.21 11.0 0.0 1.7 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.1 ETO12770.1 - 0.088 12.7 1.1 0.21 11.5 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 ETO12770.1 - 0.15 11.4 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 ETO12771.1 - 7.6e-38 129.6 0.3 8.6e-38 129.4 0.2 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.1 ETO12771.1 - 1.2e-06 28.2 0.5 3.8e-06 26.5 0.0 1.9 1 1 1 2 2 2 1 Part of AAA domain CMS1 PF14617.1 ETO12771.1 - 3.8e-05 22.8 0.1 5.3e-05 22.3 0.1 1.5 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.10 ETO12771.1 - 4.5e-05 23.3 0.0 5.9e-05 22.9 0.0 1.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 ETO12771.1 - 0.0002 20.9 0.0 0.00035 20.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.9 ETO12771.1 - 0.00024 20.7 0.0 0.0003 20.4 0.0 1.2 1 0 0 1 1 1 1 Helicase PhoH PF02562.11 ETO12771.1 - 0.0035 16.5 0.2 0.0042 16.3 0.1 1.3 1 1 0 1 1 1 1 PhoH-like protein Flavi_DEAD PF07652.9 ETO12771.1 - 0.01 15.6 0.0 0.024 14.3 0.0 1.9 1 1 0 1 1 1 0 Flavivirus DEAD domain AAA_11 PF13086.1 ETO12771.1 - 0.089 12.3 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 AAA domain TPR_12 PF13424.1 ETO12773.1 - 1.4e-08 34.5 0.0 3.1e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat Geminin PF07412.7 ETO12773.1 - 0.0038 16.9 4.6 0.0051 16.5 3.2 1.3 1 0 0 1 1 1 1 Geminin TPR_10 PF13374.1 ETO12773.1 - 0.014 15.3 0.0 0.014 15.3 0.0 2.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETO12773.1 - 0.015 15.1 0.2 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETO12773.1 - 0.027 14.2 1.1 0.045 13.5 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Spc42p PF11544.3 ETO12773.1 - 0.037 13.9 4.9 0.066 13.1 3.4 1.5 1 0 0 1 1 1 0 Spindle pole body component Spc42p TPR_11 PF13414.1 ETO12773.1 - 0.047 13.3 0.0 0.088 12.4 0.0 1.4 1 0 0 1 1 1 0 TPR repeat TPR_1 PF00515.23 ETO12773.1 - 0.051 13.1 1.1 0.12 11.9 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETO12773.1 - 0.13 12.1 0.1 0.49 10.3 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Cep57_MT_bd PF06657.8 ETO12773.1 - 0.51 10.3 8.1 0.13 12.2 2.3 2.2 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Rho_Binding PF08912.6 ETO12773.1 - 1.6 9.0 11.6 0.46 10.8 5.7 1.9 2 1 0 2 2 1 0 Rho Binding BTB PF00651.26 ETO12774.1 - 1.5e-06 28.1 0.1 5.2e-06 26.4 0.0 1.9 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.10 ETO12774.1 - 0.018 14.8 2.1 0.12 12.2 0.7 2.4 1 1 1 2 2 2 0 BTB And C-terminal Kelch Tubulin_C PF03953.12 ETO12775.1 - 4.9e-47 159.0 0.1 7.9e-47 158.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 ETO12775.1 - 8.5e-35 120.5 0.1 1.7e-34 119.5 0.1 1.6 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.1 ETO12775.1 - 0.00096 18.6 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain zf-C3HC4 PF00097.20 ETO12776.1 - 8.4e-11 41.3 9.4 1.4e-10 40.6 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO12776.1 - 4.2e-10 39.1 6.2 6.7e-10 38.4 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO12776.1 - 2.5e-09 36.8 7.7 4.1e-09 36.1 5.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO12776.1 - 1.5e-08 34.4 9.2 2.5e-08 33.7 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO12776.1 - 2e-06 27.3 8.3 3.4e-06 26.6 5.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 ETO12776.1 - 4.4e-06 26.4 8.8 8.5e-06 25.5 6.1 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 ETO12776.1 - 0.0027 17.8 8.9 0.0082 16.2 6.1 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 ETO12776.1 - 0.0056 16.4 1.6 0.012 15.4 1.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 ETO12776.1 - 0.0073 15.8 4.0 0.016 14.6 2.8 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 ETO12776.1 - 0.015 14.9 3.9 0.045 13.4 2.7 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 ETO12776.1 - 0.019 14.7 3.5 0.046 13.5 2.5 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Di19 PF05605.7 ETO12776.1 - 0.021 14.9 2.0 0.66 10.1 0.2 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.2 ETO12776.1 - 0.061 13.1 6.4 0.29 11.0 4.4 2.0 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_4 PF14570.1 ETO12776.1 - 2.6 7.7 10.6 21 4.7 7.3 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Glyco_hydro_3_C PF01915.17 ETO12777.1 - 5.9e-32 111.0 0.0 1e-31 110.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETO12777.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 Fibronectin type III-like domain PSII_Ycf12 PF05969.6 ETO12777.1 - 0.18 11.4 0.7 0.33 10.6 0.5 1.4 1 0 0 1 1 1 0 Photosystem II complex subunit Ycf12 Secretin_N_2 PF07655.8 ETO12778.1 - 0.0026 18.1 6.0 0.0069 16.7 4.2 1.8 2 0 0 2 2 2 1 Secretin N-terminal domain ELL PF10390.4 ETO12778.1 - 0.013 14.7 4.3 0.016 14.4 3.0 1.1 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL Maf1 PF09174.5 ETO12778.1 - 0.019 14.8 10.4 0.029 14.2 7.2 1.5 1 1 0 1 1 1 0 Maf1 regulator DUF3464 PF11947.3 ETO12778.1 - 1.3 8.5 3.5 2.3 7.6 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) RRM_1 PF00076.17 ETO12779.1 - 0.0065 16.0 0.0 0.021 14.4 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OST-HTH PF12872.2 ETO12780.1 - 4.7e-06 26.3 0.1 9e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 OST-HTH/LOTUS domain Pol_alpha_B_N PF08418.5 ETO12780.1 - 0.065 12.7 0.1 0.065 12.7 0.0 2.8 2 1 1 3 3 3 0 DNA polymerase alpha subunit B N-terminal DUF1777 PF08648.7 ETO12782.1 - 1.4 8.5 40.4 0.2 11.3 21.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Transformer PF06495.6 ETO12782.1 - 4.6 7.0 28.8 1.1 9.1 15.2 2.9 3 0 0 3 3 3 0 Fruit fly transformer protein Secretin_N_2 PF07655.8 ETO12783.1 - 1.3 9.4 30.2 2.5 8.5 1.7 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain Apis_Csd PF11671.3 ETO12783.1 - 1.7 8.4 13.0 0.56 9.9 5.7 2.3 2 0 0 2 2 2 0 Complementary sex determiner protein GST_N PF02798.15 ETO12784.1 - 5.4e-10 39.2 0.0 1e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Vps26 PF03643.10 ETO12785.1 - 1e-96 322.9 1.7 1.2e-96 322.7 1.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 ETO12785.1 - 0.009 15.8 1.3 1.7 8.4 0.1 3.5 3 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Imm11 PF15563.1 ETO12785.1 - 0.058 12.4 0.1 0.33 10.0 0.0 2.0 2 0 0 2 2 2 0 Immunity protein 11 MIP-T3 PF10243.4 ETO12786.1 - 0.79 8.1 42.8 1 7.7 29.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Membralin PF09746.4 ETO12786.1 - 2.6 7.0 6.5 3.2 6.6 4.5 1.2 1 0 0 1 1 1 0 Tumour-associated protein SOBP PF15279.1 ETO12786.1 - 4 7.7 18.9 5 7.4 13.1 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF1582 PF07621.6 ETO12788.1 - 0.15 12.0 1.7 0.46 10.5 1.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1582) Mei4 PF13971.1 ETO12789.1 - 0.22 10.4 2.3 0.26 10.1 1.6 1.2 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 Glt_symporter PF03616.9 ETO12789.1 - 0.42 9.0 4.2 0.16 10.4 1.3 1.4 1 1 1 2 2 2 0 Sodium/glutamate symporter Vfa1 PF08432.5 ETO12790.1 - 0.069 13.1 14.9 0.089 12.8 10.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 ETO12790.1 - 0.48 8.3 9.6 0.58 8.1 6.7 1.0 1 0 0 1 1 1 0 CDC45-like protein YqfQ PF14181.1 ETO12790.1 - 2.8 7.9 5.5 3.3 7.7 3.8 1.2 1 0 0 1 1 1 0 YqfQ-like protein Peptidase_S49_N PF08496.5 ETO12790.1 - 5.4 6.7 8.3 6.9 6.4 5.7 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3987 PF13148.1 ETO12790.1 - 7.9 4.9 7.6 8.7 4.7 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) LRR_6 PF13516.1 ETO12791.1 - 2.8e-23 79.3 10.5 0.0051 16.7 0.0 7.4 7 0 0 7 7 7 6 Leucine Rich repeat LRR_1 PF00560.28 ETO12791.1 - 7.9e-09 34.3 7.6 1.9 8.8 0.0 6.8 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_4 PF12799.2 ETO12791.1 - 1.4e-07 30.9 9.1 0.014 15.0 0.1 5.1 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 ETO12791.1 - 7e-06 25.4 13.7 4.3 7.9 0.0 7.5 8 0 0 8 8 8 1 Leucine rich repeat LRR_8 PF13855.1 ETO12791.1 - 2.7e-05 23.8 8.4 0.051 13.3 0.1 5.1 5 0 0 5 5 5 3 Leucine rich repeat Methyltransf_21 PF05050.7 ETO12795.1 - 1.1e-12 48.1 0.1 6.5e-12 45.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase FkbM domain GXWXG PF14231.1 ETO12795.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 GXWXG protein SecE PF00584.15 ETO12795.1 - 0.17 11.5 0.4 1 8.9 0.2 2.0 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex YMF19 PF02326.10 ETO12796.1 - 0.036 14.6 1.6 0.073 13.6 1.1 1.4 1 0 0 1 1 1 0 Plant ATP synthase F0 RBP_receptor PF14752.1 ETO12796.1 - 0.037 12.3 0.3 0.045 12.0 0.2 1.1 1 0 0 1 1 1 0 Retinol binding protein receptor ABC2_membrane_5 PF13346.1 ETO12796.1 - 0.27 10.4 8.9 0.34 10.1 6.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF997 PF06196.7 ETO12796.1 - 0.72 9.4 4.1 2.6 7.6 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF997) Ras PF00071.17 ETO12797.1 - 7.3e-13 48.2 1.3 6.4e-05 22.3 0.1 4.1 3 1 0 3 3 3 3 Ras family Miro PF08477.8 ETO12797.1 - 6.3e-08 33.1 6.4 0.0005 20.5 0.0 4.0 3 1 1 4 4 4 2 Miro-like protein Arf PF00025.16 ETO12797.1 - 0.0032 16.7 0.2 6.7 5.9 0.0 3.7 4 0 0 4 4 4 2 ADP-ribosylation factor family DUF3439 PF11921.3 ETO12797.1 - 7.6 6.3 18.8 1.8 8.3 10.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) MFS_1 PF07690.11 ETO12798.1 - 5.6e-07 28.6 5.4 5.6e-07 28.6 3.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 ETO12798.1 - 0.026 14.5 0.4 0.048 13.6 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1228) DUF373 PF04123.8 ETO12798.1 - 0.13 11.2 1.6 0.21 10.5 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) ubiquitin PF00240.18 ETO12799.1 - 1.3e-34 117.3 0.7 5.3e-34 115.4 0.4 1.9 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 ETO12799.1 - 6.3e-19 67.4 0.3 1e-18 66.7 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_S27 PF01599.14 ETO12799.1 - 7.7e-19 67.2 3.7 1.4e-18 66.4 2.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Ubiquitin_2 PF14560.1 ETO12799.1 - 4.7e-06 26.7 0.1 2.5e-05 24.4 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 ETO12799.1 - 0.0005 19.9 0.4 0.001 18.9 0.3 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 ETO12799.1 - 0.0013 18.8 0.1 0.0021 18.2 0.1 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Telomere_Sde2 PF13019.1 ETO12799.1 - 0.0042 16.7 0.4 0.0083 15.8 0.0 1.6 1 1 1 2 2 2 1 Telomere stability and silencing DUF2870 PF11069.3 ETO12799.1 - 0.057 13.4 0.2 0.19 11.7 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 ETO12799.1 - 0.059 13.2 0.1 0.098 12.5 0.0 1.4 1 0 0 1 1 1 0 GLUT4 regulating protein TUG Plexin_cytopl PF08337.7 ETO12799.1 - 0.11 10.7 0.1 2.2 6.4 0.0 2.0 2 0 0 2 2 2 0 Plexin cytoplasmic RasGAP domain AAA_12 PF13087.1 ETO12800.1 - 1.8e-57 193.9 0.0 2.7e-57 193.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 ETO12800.1 - 1.7e-26 93.2 1.3 2.1e-17 63.5 0.1 2.5 2 1 1 3 3 3 2 AAA domain AAA_19 PF13245.1 ETO12800.1 - 0.0011 18.6 0.0 0.0031 17.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 ETO12800.1 - 0.0013 18.3 0.0 0.0028 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 ETO12800.1 - 0.0031 17.0 0.0 1.9 7.9 0.0 2.2 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase DUF4050 PF13259.1 ETO12800.1 - 0.06 13.2 0.1 0.097 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Secretin_N_2 PF07655.8 ETO12801.1 - 0.026 14.9 8.0 0.038 14.3 5.5 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain Nro1 PF12753.2 ETO12801.1 - 0.032 13.1 4.5 0.04 12.8 3.1 1.1 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 DUF1764 PF08576.5 ETO12801.1 - 0.12 13.1 4.5 0.14 12.9 3.1 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Packaging_FI PF14000.1 ETO12801.1 - 0.18 11.9 2.7 0.25 11.5 1.9 1.3 1 0 0 1 1 1 0 DNA packaging protein FI NST1 PF13945.1 ETO12801.1 - 0.51 10.3 9.4 0.59 10.1 6.5 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator RP-C_C PF11800.3 ETO12801.1 - 0.86 9.2 4.4 0.92 9.1 3.1 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Sec62 PF03839.11 ETO12801.1 - 1.2 8.4 4.7 1.3 8.3 3.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Methyltransf_12 PF08242.7 ETO12801.1 - 3.1 8.3 5.0 7.5 7.1 3.5 1.8 1 1 0 1 1 1 0 Methyltransferase domain Folate_carrier PF01770.13 ETO12801.1 - 3.2 6.1 4.5 3.8 5.9 3.1 1.1 1 0 0 1 1 1 0 Reduced folate carrier DUF912 PF06024.7 ETO12801.1 - 4 7.5 6.6 5.9 6.9 4.6 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Zip PF02535.17 ETO12801.1 - 9.3 5.1 7.4 11 4.8 5.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter TPR_12 PF13424.1 ETO12802.1 - 5.3e-83 273.0 19.9 1.5e-21 76.0 0.2 4.7 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.23 ETO12802.1 - 1e-38 129.3 32.3 2e-08 33.5 0.1 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_11 PF13414.1 ETO12802.1 - 2.8e-38 129.3 17.8 8.3e-14 50.9 0.8 3.6 3 1 0 3 3 3 3 TPR repeat TPR_7 PF13176.1 ETO12802.1 - 1.6e-36 121.2 6.4 4.1e-06 26.1 0.1 6.7 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.1 ETO12802.1 - 1.7e-34 116.7 0.0 3.6e-07 29.8 0.0 6.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETO12802.1 - 2.8e-29 98.6 22.7 1.5e-05 24.5 0.0 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETO12802.1 - 2.2e-25 86.4 35.8 5.8e-07 28.8 0.7 6.8 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.1 ETO12802.1 - 9.5e-14 50.3 16.7 0.0014 18.6 0.1 6.8 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO12802.1 - 3.2e-09 37.2 0.0 0.016 15.8 0.0 4.3 4 1 0 4 4 4 2 Tetratricopeptide repeat MIT PF04212.13 ETO12802.1 - 8.8e-09 35.1 17.0 0.1 12.5 0.0 6.1 5 1 1 6 6 6 4 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 ETO12802.1 - 9.7e-09 35.1 4.2 1.2 9.6 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO12802.1 - 1.8e-08 34.2 0.0 4 8.3 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat DUF2225 PF09986.4 ETO12802.1 - 0.00014 21.3 21.4 0.61 9.5 1.1 5.1 3 1 1 4 4 4 2 Uncharacterized protein conserved in bacteria (DUF2225) SHNi-TPR PF10516.4 ETO12802.1 - 0.00014 20.9 0.3 2.9 7.2 0.0 4.3 4 0 0 4 4 4 1 SHNi-TPR RPN7 PF10602.4 ETO12802.1 - 0.001 18.4 8.9 0.31 10.4 0.3 4.2 2 1 2 4 4 4 2 26S proteasome subunit RPN7 PPR PF01535.15 ETO12802.1 - 0.051 13.5 10.2 0.95 9.5 0.0 5.6 6 0 0 6 6 6 0 PPR repeat SMI1_KNR4 PF09346.5 ETO12802.1 - 0.42 10.6 12.0 0.034 14.1 1.2 3.1 3 0 0 3 3 3 0 SMI1 / KNR4 family (SUKH-1) Kelch_1 PF01344.20 ETO12802.1 - 4.2 7.0 13.0 4.3 6.9 0.1 4.3 5 0 0 5 5 5 0 Kelch motif DUF3421 PF11901.3 ETO12803.1 - 0.019 14.6 0.4 0.054 13.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3421) DUF3915 PF13054.1 ETO12804.1 - 0.071 13.0 0.0 0.42 10.5 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3915) Tubulin PF00091.20 ETO12807.1 - 2e-46 158.5 0.1 2.9e-23 82.8 0.0 2.1 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.4 ETO12807.1 - 5.7e-06 26.3 0.0 1.1e-05 25.4 0.0 1.6 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain DBP10CT PF08147.7 ETO12807.1 - 0.14 11.9 2.1 0.21 11.3 0.2 2.1 2 0 0 2 2 2 0 DBP10CT (NUC160) domain Pre-SET PF05033.11 ETO12807.1 - 0.37 11.0 3.9 3.3 8.0 2.7 2.3 1 1 0 1 1 1 0 Pre-SET motif Tubulin PF00091.20 ETO12808.1 - 2.9e-11 43.6 0.1 3.7e-11 43.2 0.1 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO12808.1 - 0.00089 19.2 0.6 0.0019 18.2 0.1 1.8 2 1 0 2 2 2 1 Tubulin C-terminal domain PHB_acc_N PF07879.6 ETO12808.1 - 0.092 12.4 0.2 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 PHB/PHA accumulation regulator DNA-binding domain TraS PF10624.4 ETO12808.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS DUF4477 PF14780.1 ETO12810.1 - 0.0031 16.9 2.5 0.0031 16.9 1.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4477) Baculo_PEP_N PF04512.7 ETO12810.1 - 0.042 13.8 0.1 0.53 10.2 0.0 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, N terminus DUF2500 PF10694.4 ETO12811.1 - 0.14 12.1 0.7 0.32 11.0 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) DUF1179 PF06678.6 ETO12811.1 - 1.7 8.9 9.4 1.6 9.0 5.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1179) Pex14_N PF04695.8 ETO12812.1 - 0.00098 19.1 0.3 0.00098 19.1 0.2 4.2 3 1 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Trypan_PARP PF05887.6 ETO12812.1 - 0.0016 18.2 4.4 0.0016 18.2 3.1 2.1 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) Cytochrom_B_N PF00033.14 ETO12812.1 - 0.0036 16.6 0.0 1.4 8.2 0.0 2.6 2 0 0 2 2 2 2 Cytochrome b(N-terminal)/b6/petB Neisseria_TspB PF05616.8 ETO12812.1 - 0.03 12.7 13.0 0.068 11.5 7.1 2.2 2 0 0 2 2 2 0 Neisseria meningitidis TspB protein cNMP_binding PF00027.24 ETO12813.1 - 5.2e-37 125.5 0.2 6.1e-17 61.2 0.0 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Hema_stalk PF08720.5 ETO12813.1 - 0.011 15.2 0.4 0.021 14.3 0.3 1.4 1 0 0 1 1 1 0 Influenza C hemagglutinin stalk Pkinase PF00069.20 ETO12813.1 - 0.011 14.8 0.6 0.033 13.3 0.4 1.9 1 0 0 1 1 1 0 Protein kinase domain Bac_rhamnosid_N PF08531.5 ETO12813.1 - 0.077 12.5 0.0 2.2 7.7 0.0 2.6 2 0 0 2 2 2 0 Alpha-L-rhamnosidase N-terminal domain CDK2AP PF09806.4 ETO12815.1 - 0.05 13.8 3.5 0.055 13.7 2.4 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Chorion_3 PF05387.6 ETO12815.1 - 0.47 9.8 8.3 0.71 9.2 5.7 1.3 1 0 0 1 1 1 0 Chorion family 3 DUF755 PF05501.6 ETO12815.1 - 2.1 8.4 18.5 0.11 12.6 9.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Macoilin PF09726.4 ETO12815.1 - 7.5 4.6 9.9 8.2 4.5 6.9 1.1 1 0 0 1 1 1 0 Transmembrane protein RAP1 PF07218.6 ETO12815.1 - 9 4.2 9.2 8.8 4.2 6.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MtrF PF09472.5 ETO12817.1 - 0.003 16.7 0.5 0.0064 15.6 0.4 1.5 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) dsrm PF00035.20 ETO12818.1 - 0.0049 17.4 0.7 0.019 15.5 0.0 2.2 2 0 0 2 2 2 1 Double-stranded RNA binding motif VPS11_C PF12451.3 ETO12818.1 - 0.014 15.2 0.7 0.17 11.7 0.0 2.5 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal DUF2809 PF10990.3 ETO12818.1 - 0.035 14.4 0.2 0.064 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2809) Peptidase_C48 PF02902.14 ETO12819.1 - 3.7e-12 46.3 0.6 1.2e-11 44.6 0.3 2.1 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain G-7-MTase PF12803.2 ETO12819.1 - 0.023 13.8 0.2 0.033 13.3 0.1 1.1 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) MKT1_C PF12246.3 ETO12820.1 - 1.5e-10 40.5 0.2 3e-10 39.5 0.2 1.5 1 1 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 ETO12821.1 - 4.7e-09 36.4 0.0 1.1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication ABC2_membrane_3 PF12698.2 ETO12822.1 - 0.01 14.9 9.2 0.01 14.9 6.3 2.4 3 0 0 3 3 3 0 ABC-2 family transporter protein AAA_2 PF07724.9 ETO12823.1 - 3.4e-24 85.6 0.0 3.9e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 ETO12823.1 - 3.7e-07 30.3 0.0 4.4e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DctQ PF04290.7 ETO12824.1 - 2.6 7.8 19.1 0.87 9.3 0.5 3.3 3 1 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component SR-25 PF10500.4 ETO12826.1 - 0.16 11.4 15.1 0.22 10.9 10.2 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Oxygenase-NA PF09859.4 ETO12826.1 - 0.49 9.6 4.7 0.78 9.0 3.3 1.2 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA Lin-8 PF03353.10 ETO12826.1 - 3.1 6.9 9.8 3.9 6.6 6.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist MRI PF15325.1 ETO12826.1 - 8.5 7.4 9.4 2.2 9.2 3.8 1.9 2 0 0 2 2 2 0 Modulator of retrovirus infection E_Pc_C PF06752.7 ETO12826.1 - 9.4 5.6 20.2 0.66 9.4 8.2 2.2 2 0 0 2 2 2 0 Enhancer of Polycomb C-terminus PAG PF15347.1 ETO12827.1 - 0.019 14.1 0.5 0.034 13.2 0.0 1.5 1 1 1 2 2 2 0 Phosphoprotein associated with glycosphingolipid-enriched RNase_HII PF01351.13 ETO12828.1 - 9.4e-29 100.4 0.1 5.5e-27 94.6 0.1 2.4 1 1 0 1 1 1 1 Ribonuclease HII DUF2695 PF10905.3 ETO12828.1 - 0.088 12.5 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) Citrate_synt PF00285.16 ETO12829.1 - 5e-92 308.3 0.0 6.2e-92 308.0 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase XH PF03469.9 ETO12829.1 - 0.0012 18.4 0.0 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 XH domain Ribosomal_L30_N PF08079.7 ETO12830.1 - 0.0011 18.9 11.4 0.0011 18.9 7.9 3.2 2 1 1 3 3 3 1 Ribosomal L30 N-terminal domain SID-1_RNA_chan PF13965.1 ETO12830.1 - 0.17 10.0 7.4 0.2 9.7 5.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FRG1 PF06229.7 ETO12830.1 - 0.9 8.9 15.4 0.021 14.3 3.2 2.0 2 0 0 2 2 2 0 FRG1-like family Tau95 PF09734.4 ETO12830.1 - 5.8 6.1 8.8 7.8 5.7 6.1 1.1 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit Ribosomal_L30 PF00327.15 ETO12831.1 - 3.7e-15 55.2 1.8 6.9e-15 54.3 0.5 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e NIF PF03031.13 ETO12832.1 - 3.1e-09 36.6 0.4 1.7e-08 34.2 0.0 2.2 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase DUF1796 PF08795.5 ETO12833.1 - 0.021 14.4 2.2 0.21 11.2 0.1 2.3 2 1 0 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) WD40 PF00400.27 ETO12836.1 - 2.5e-138 445.6 56.2 1.7e-12 46.7 0.5 17.0 17 0 0 17 17 17 16 WD domain, G-beta repeat PD40 PF07676.7 ETO12836.1 - 3.3e-06 26.6 25.9 0.01 15.4 0.0 9.8 12 0 0 12 12 12 2 WD40-like Beta Propeller Repeat Pentapeptide PF00805.17 ETO12836.1 - 8.6e-06 24.8 0.7 1.6e-05 23.9 0.5 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) DUF1938 PF09153.5 ETO12836.1 - 1.8e-05 24.4 1.8 0.015 15.1 0.1 4.2 4 0 0 4 4 4 2 Domain of unknown function (DUF1938) Mid2 PF04478.7 ETO12836.1 - 2.4e-05 23.7 17.1 0.34 10.3 0.0 8.3 5 2 5 10 10 10 3 Mid2 like cell wall stress sensor Pentapeptide_4 PF13599.1 ETO12836.1 - 3.7e-05 23.4 0.2 0.0001 22.0 0.1 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 ETO12836.1 - 0.00036 20.3 0.4 0.001 18.8 0.3 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Resistin PF06954.6 ETO12836.1 - 0.0076 16.5 2.9 29 5.0 0.0 5.4 4 3 2 6 6 6 0 Resistin Phage_rep_O PF04492.8 ETO12837.1 - 0.043 14.0 0.2 0.091 12.9 0.1 1.5 2 0 0 2 2 2 0 Bacteriophage replication protein O FlaA PF04620.7 ETO12837.1 - 0.051 12.9 0.2 0.064 12.6 0.1 1.1 1 0 0 1 1 1 0 Flagellar filament outer layer protein Flaa BCS1_N PF08740.6 ETO12839.1 - 3.7e-17 62.5 0.5 7.8e-17 61.4 0.0 1.8 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 ETO12839.1 - 7.2e-14 52.1 0.0 1.7e-11 44.4 0.0 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 ETO12839.1 - 6.2e-05 22.4 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO12839.1 - 0.00046 20.9 0.0 0.0033 18.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETO12839.1 - 0.0029 17.6 0.1 0.0074 16.2 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 ETO12839.1 - 0.0065 16.2 0.0 0.043 13.5 0.0 2.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 ETO12839.1 - 0.011 15.2 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.8 ETO12839.1 - 0.023 13.6 0.0 0.037 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) KaiC PF06745.8 ETO12839.1 - 0.032 13.3 0.0 0.059 12.4 0.0 1.4 1 0 0 1 1 1 0 KaiC RNA_helicase PF00910.17 ETO12839.1 - 0.054 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Pex14_N PF04695.8 ETO12839.1 - 0.054 13.5 2.2 0.22 11.5 0.1 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AAA_22 PF13401.1 ETO12839.1 - 0.1 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Bromodomain PF00439.20 ETO12840.1 - 0.00019 21.2 0.4 0.00055 19.8 0.3 1.8 1 0 0 1 1 1 1 Bromodomain SR-25 PF10500.4 ETO12840.1 - 0.00096 18.6 2.9 0.00096 18.6 2.0 3.4 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein MCR_alpha PF02249.12 ETO12840.1 - 0.63 10.0 6.3 0.52 10.3 0.2 2.7 3 0 0 3 3 3 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain Chorion_2 PF03964.10 ETO12840.1 - 3.8 8.1 18.8 5.2 7.6 2.2 3.3 3 0 0 3 3 3 0 Chorion family 2 RAP1 PF07218.6 ETO12840.1 - 7.2 4.5 19.5 0.047 11.7 0.5 2.5 3 0 0 3 3 3 0 Rhoptry-associated protein 1 (RAP-1) PH PF00169.24 ETO12841.1 - 6.6e-06 26.2 1.5 1.7e-05 24.9 1.0 1.8 1 1 0 1 1 1 1 PH domain PH_11 PF15413.1 ETO12841.1 - 0.0031 17.7 0.5 0.004 17.3 0.3 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain zf-C2H2 PF00096.21 ETO12842.1 - 0.013 15.8 17.1 1.5 9.3 0.9 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 ETO12842.1 - 0.032 14.3 3.7 0.18 11.9 0.8 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 ETO12842.1 - 3.9 7.8 7.2 13 6.1 0.3 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 ETO12842.1 - 7.6 7.1 12.5 8.9 6.9 0.2 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Syntaxin-6_N PF09177.6 ETO12843.1 - 3.6e-12 46.5 2.4 3.6e-12 46.5 1.7 3.0 2 2 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 ETO12843.1 - 1.4e-08 34.3 6.9 1.4e-08 34.3 4.7 3.5 3 1 0 3 3 3 1 SNARE domain Laminin_II PF06009.7 ETO12843.1 - 0.0051 16.5 18.4 0.042 13.6 2.3 3.1 1 1 2 3 3 3 2 Laminin Domain II Syntaxin PF00804.20 ETO12843.1 - 0.0073 16.4 10.1 0.0073 16.4 7.0 4.1 1 1 1 2 2 1 1 Syntaxin HalX PF08663.5 ETO12843.1 - 0.0092 15.9 5.0 0.52 10.3 0.1 3.1 3 0 0 3 3 3 2 HalX domain DUF1474 PF07342.6 ETO12843.1 - 0.023 14.9 5.1 0.91 9.7 0.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1474) PfUIS3 PF11567.3 ETO12843.1 - 0.031 14.4 1.2 0.031 14.4 0.8 2.7 1 1 0 2 2 2 0 Plasmodium falciparum UIS3 membrane protein Bromo_TP PF07524.8 ETO12843.1 - 0.069 12.8 0.4 6.8 6.5 0.0 2.9 2 1 0 2 2 2 0 Bromodomain associated Reo_sigmaC PF04582.7 ETO12843.1 - 0.27 10.3 6.2 2.4 7.2 0.1 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein UPF0184 PF03670.8 ETO12843.1 - 0.44 10.7 5.7 0.76 10.0 0.3 3.1 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) CCDC144C PF14915.1 ETO12843.1 - 0.51 9.2 31.3 0.36 9.6 4.3 2.0 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region TMP_2 PF06791.8 ETO12843.1 - 1.5 8.4 8.5 0.68 9.5 0.6 2.9 2 1 1 3 3 3 0 Prophage tail length tape measure protein ALMT PF11744.3 ETO12843.1 - 2.2 6.8 12.6 4.2 5.9 8.7 1.6 1 1 0 1 1 1 0 Aluminium activated malate transporter RRF_GI PF12614.3 ETO12843.1 - 3.3 7.5 18.8 0.43 10.3 3.5 3.3 1 1 1 2 2 2 0 Ribosome recycling factor WXG100 PF06013.7 ETO12843.1 - 6.4 6.8 20.5 1.5 8.9 1.8 4.3 3 2 0 3 3 3 0 Proteins of 100 residues with WXG Sas10_Utp3 PF04000.10 ETO12843.1 - 7 6.9 7.0 11 6.3 0.1 3.4 1 1 2 4 4 4 0 Sas10/Utp3/C1D family CCDC84 PF14968.1 ETO12843.1 - 7.3 5.9 15.0 7.1 6.0 9.5 1.6 1 1 0 1 1 1 0 Coiled coil protein 84 LEDGF PF11467.3 ETO12843.1 - 9.6 5.9 14.8 0.18 11.5 3.7 2.5 1 1 2 3 3 3 0 Lens epithelium-derived growth factor (LEDGF) DUF648 PF04890.8 ETO12844.1 - 0.049 12.7 0.8 0.057 12.5 0.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF648) MgtE_N PF03448.12 ETO12844.1 - 0.078 13.3 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 MgtE intracellular N domain PRP38_assoc PF12871.2 ETO12844.1 - 0.086 13.3 5.7 0.14 12.7 3.9 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Bravo_FIGEY PF13882.1 ETO12844.1 - 0.67 10.9 5.8 1.3 9.9 0.7 2.2 2 0 0 2 2 2 0 Bravo-like intracellular region Pex16 PF08610.5 ETO12844.1 - 1.1 8.1 3.4 1.6 7.6 2.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) PRKCSH PF07915.8 ETO12845.1 - 0.014 16.1 2.3 0.014 16.1 1.6 2.4 2 1 0 2 2 2 0 Glucosidase II beta subunit-like protein Peptidase_M1 PF01433.15 ETO12847.1 - 2.1e-19 69.8 0.1 1.2e-08 34.5 0.0 2.4 2 0 0 2 2 2 2 Peptidase family M1 Peptidase_MA_2 PF13485.1 ETO12847.1 - 2.1e-13 50.4 0.0 4.1e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Leuk-A4-hydro_C PF09127.6 ETO12847.1 - 0.00031 20.3 0.8 0.023 14.3 0.3 2.4 2 0 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M61 PF05299.7 ETO12847.1 - 0.24 11.3 2.4 14 5.6 1.7 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Peptidase_M1 PF01433.15 ETO12848.1 - 3.1e-34 118.7 0.0 3.7e-34 118.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M1 LRR_adjacent PF08191.6 ETO12848.1 - 0.042 13.5 0.2 9.7 6.0 0.1 3.2 3 0 0 3 3 3 0 LRR adjacent DUF1664 PF07889.7 ETO12849.1 - 0.0097 15.7 7.1 0.0097 15.7 4.9 5.8 3 2 4 7 7 7 1 Protein of unknown function (DUF1664) DUF4047 PF13256.1 ETO12849.1 - 0.013 15.4 1.0 0.013 15.4 0.7 5.8 2 1 3 5 5 5 0 Domain of unknown function (DUF4047) IncA PF04156.9 ETO12850.1 - 0.00013 21.6 2.7 0.00018 21.1 1.9 1.1 1 0 0 1 1 1 1 IncA protein Filament PF00038.16 ETO12850.1 - 0.00048 19.6 4.2 0.00069 19.1 2.9 1.4 1 0 0 1 1 1 1 Intermediate filament protein DUF4200 PF13863.1 ETO12850.1 - 0.0041 17.0 10.6 0.0079 16.1 7.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) FliJ PF02050.11 ETO12850.1 - 0.0042 17.1 9.0 0.21 11.6 2.3 2.2 1 1 1 2 2 2 2 Flagellar FliJ protein PspA_IM30 PF04012.7 ETO12850.1 - 0.0042 16.4 6.1 0.0068 15.7 4.2 1.3 1 0 0 1 1 1 1 PspA/IM30 family DUF4140 PF13600.1 ETO12850.1 - 0.0058 17.0 1.4 0.19 12.1 0.1 2.3 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) Geminin PF07412.7 ETO12850.1 - 0.016 14.8 3.4 0.016 14.8 1.8 1.3 1 1 0 1 1 1 0 Geminin DUF1664 PF07889.7 ETO12850.1 - 0.017 14.8 3.1 0.17 11.6 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Flagellin_C PF00700.16 ETO12850.1 - 0.019 15.1 4.0 1.6 8.9 0.0 3.2 3 0 0 3 3 3 0 Bacterial flagellin C-terminal helical region Fib_alpha PF08702.5 ETO12850.1 - 0.021 14.9 6.2 0.034 14.2 3.7 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Reo_sigmaC PF04582.7 ETO12850.1 - 0.023 13.8 0.2 0.28 10.3 0.0 1.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein COG5 PF10392.4 ETO12850.1 - 0.035 14.0 1.0 0.11 12.4 0.2 2.0 1 1 0 2 2 2 0 Golgi transport complex subunit 5 APG6 PF04111.7 ETO12850.1 - 0.036 13.1 8.9 0.062 12.3 6.1 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 ETO12850.1 - 0.036 13.9 8.9 0.16 11.8 6.2 1.9 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Apolipoprotein PF01442.13 ETO12850.1 - 0.051 13.0 3.7 0.089 12.2 2.5 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain TBPIP PF07106.8 ETO12850.1 - 0.053 13.0 8.7 0.18 11.3 1.0 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HrpB7 PF09486.5 ETO12850.1 - 0.054 13.4 1.6 7.9 6.3 0.2 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Vac_Fusion PF02346.11 ETO12850.1 - 0.056 12.8 1.4 0.16 11.4 0.3 2.3 2 0 0 2 2 2 0 Chordopoxvirus fusion protein FlaC_arch PF05377.6 ETO12850.1 - 0.076 12.9 3.8 4.3 7.2 0.1 2.9 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Phage_GP20 PF06810.6 ETO12850.1 - 0.083 12.3 6.9 0.095 12.1 1.7 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 ATG16 PF08614.6 ETO12850.1 - 0.093 12.5 7.7 3.6 7.3 1.4 2.9 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) CorA PF01544.13 ETO12850.1 - 0.11 11.5 1.9 0.18 10.8 1.3 1.3 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Noelin-1 PF12308.3 ETO12850.1 - 0.18 11.6 2.8 0.84 9.4 0.1 2.6 1 1 2 3 3 3 0 Neurogenesis glycoprotein V_ATPase_I PF01496.14 ETO12850.1 - 0.19 9.5 7.9 0.23 9.2 5.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4618 PF15397.1 ETO12850.1 - 0.19 11.0 8.9 0.15 11.3 2.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) Tropomyosin_1 PF12718.2 ETO12850.1 - 0.22 11.3 9.3 2.7 7.8 6.4 2.2 1 1 0 1 1 1 0 Tropomyosin like ADIP PF11559.3 ETO12850.1 - 0.24 11.2 8.6 1.6 8.6 2.3 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2730 PF10805.3 ETO12850.1 - 0.25 11.1 3.3 0.79 9.4 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) SlyX PF04102.7 ETO12850.1 - 0.33 11.3 3.4 11 6.4 0.2 3.1 1 1 1 2 2 2 0 SlyX DUF2205 PF10224.4 ETO12850.1 - 0.35 10.4 3.9 0.57 9.7 2.2 1.8 1 1 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) Syntaxin-6_N PF09177.6 ETO12850.1 - 0.4 11.1 4.3 1.6 9.1 2.9 2.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal TMF_DNA_bd PF12329.3 ETO12850.1 - 0.44 10.3 9.1 4.1 7.2 1.8 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF489 PF04356.7 ETO12850.1 - 0.45 10.0 3.5 4.5 6.8 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF489) MCPsignal PF00015.16 ETO12850.1 - 0.45 10.0 5.7 1.1 8.7 2.1 2.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain TPR_MLP1_2 PF07926.7 ETO12850.1 - 0.66 9.7 9.0 2.5 7.8 1.3 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DivIC PF04977.10 ETO12850.1 - 0.77 9.2 5.5 1 8.8 0.9 2.5 2 0 0 2 2 2 0 Septum formation initiator DUF3847 PF12958.2 ETO12850.1 - 1.7 8.4 6.1 11 5.9 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) CENP-Q PF13094.1 ETO12850.1 - 2.6 8.0 8.6 20 5.1 1.8 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit FlxA PF14282.1 ETO12850.1 - 3 7.8 7.5 0.92 9.4 1.6 2.4 1 1 2 3 3 3 0 FlxA-like protein DUF972 PF06156.8 ETO12850.1 - 7.5 6.9 9.1 5.6 7.3 2.6 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF972) CENP-B_dimeris PF09026.5 ETO12851.1 - 0.01 16.0 2.6 1.1 9.5 0.1 3.5 3 0 0 3 3 3 0 Centromere protein B dimerisation domain PYST-C1 PF09690.5 ETO12851.1 - 1.9 8.1 0.0 1.9 8.1 0.0 5.4 6 1 0 6 6 6 0 Plasmodium yoelii subtelomeric region (PYST-C1) Utp14 PF04615.8 ETO12853.1 - 0.011 13.8 34.6 0.014 13.6 24.0 1.1 1 0 0 1 1 1 0 Utp14 protein Hid1 PF12722.2 ETO12853.1 - 0.011 13.4 30.4 0.016 12.9 21.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Daxx PF03344.10 ETO12853.1 - 0.12 10.8 28.1 0.15 10.4 19.5 1.1 1 0 0 1 1 1 0 Daxx Family MIP-T3 PF10243.4 ETO12853.1 - 0.45 8.9 32.9 0.65 8.4 22.8 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 BSP_II PF05432.6 ETO12853.1 - 0.74 9.0 39.6 1.1 8.4 27.4 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) eIF-3c_N PF05470.7 ETO12853.1 - 1.1 7.2 22.7 1.6 6.6 15.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF4551 PF15087.1 ETO12853.1 - 5.6 5.2 17.5 6.7 4.9 12.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF1675 PF07897.6 ETO12853.1 - 7.8 6.2 22.2 11 5.8 15.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Mucin PF01456.12 ETO12853.1 - 9.6 5.9 19.3 15 5.3 13.4 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein NUDIX PF00293.23 ETO12854.1 - 1.8e-14 53.5 0.0 4.5e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 NUDIX domain Beta-lactamase PF00144.19 ETO12854.1 - 1.4e-09 37.4 0.0 2.1e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Daxx PF03344.10 ETO12856.1 - 0.15 10.5 32.2 0.24 9.8 22.3 1.3 1 0 0 1 1 1 0 Daxx Family YL1 PF05764.8 ETO12856.1 - 1.9 8.0 28.4 5.2 6.6 19.7 1.7 1 0 0 1 1 1 0 YL1 nuclear protein polyprenyl_synt PF00348.12 ETO12857.1 - 1.6e-48 164.8 0.7 1.1e-29 103.0 0.0 2.4 2 0 0 2 2 2 2 Polyprenyl synthetase SAM_1 PF00536.25 ETO12858.1 - 0.0017 18.5 0.1 1.6 8.9 0.0 2.3 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO12858.1 - 0.0056 16.5 0.0 4.3 7.2 0.0 2.3 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) DRMBL PF07522.9 ETO12858.1 - 0.053 13.5 0.7 0.16 11.9 0.1 2.0 2 0 0 2 2 2 0 DNA repair metallo-beta-lactamase SAM_PNT PF02198.11 ETO12858.1 - 0.088 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Minor_capsid_3 PF12691.2 ETO12858.1 - 0.094 12.4 0.9 0.15 11.7 0.1 1.7 2 0 0 2 2 2 0 Minor capsid protein from bacteriophage DUF4375 PF14300.1 ETO12858.1 - 0.38 10.7 2.5 39 4.2 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4375) TMEM154 PF15102.1 ETO12860.1 - 0.00046 19.9 0.3 0.00046 19.9 0.2 2.0 2 0 0 2 2 2 1 TMEM154 protein family DUF3753 PF12575.3 ETO12860.1 - 0.0013 18.5 4.3 0.0013 18.5 3.0 1.8 2 0 0 2 2 1 1 Protein of unknown function (DUF3753) Oxidored_q3 PF00499.15 ETO12860.1 - 0.0033 17.2 2.8 0.0068 16.1 1.9 1.5 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF4448 PF14610.1 ETO12860.1 - 0.0034 16.8 0.2 0.011 15.2 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF1183 PF06682.7 ETO12860.1 - 0.027 14.1 0.4 0.027 14.1 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) ODV-E18 PF10717.4 ETO12860.1 - 0.03 13.7 8.8 0.13 11.7 6.1 2.1 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF2615 PF11027.3 ETO12860.1 - 0.054 13.4 0.8 0.15 12.0 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) O-ag_pol_Wzy PF14296.1 ETO12860.1 - 0.073 11.6 7.8 0.12 10.9 5.4 1.2 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy EphA2_TM PF14575.1 ETO12860.1 - 0.079 13.3 0.1 0.33 11.3 0.1 2.0 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PQQ_3 PF13570.1 ETO12860.1 - 0.09 13.0 0.0 5.1 7.5 0.0 2.8 3 0 0 3 3 3 0 PQQ-like domain OppC_N PF12911.2 ETO12860.1 - 0.12 11.7 3.6 0.34 10.3 2.5 1.7 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C PspB PF06667.7 ETO12860.1 - 0.2 11.6 0.2 0.2 11.6 0.1 2.3 3 0 0 3 3 2 0 Phage shock protein B Tmemb_9 PF05434.6 ETO12860.1 - 0.34 10.6 7.7 0.96 9.1 5.3 1.8 1 1 0 1 1 1 0 TMEM9 Sigma_reg_N PF13800.1 ETO12860.1 - 0.62 10.1 12.1 0.41 10.7 6.0 2.3 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF1510 PF07423.6 ETO12860.1 - 1.4 8.2 11.6 0.027 13.8 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) ATP-synt_8 PF00895.15 ETO12860.1 - 4.5 7.5 8.5 1.1 9.4 2.1 3.0 2 0 0 2 2 2 0 ATP synthase protein 8 Vma12 PF11712.3 ETO12860.1 - 5.5 6.6 8.5 0.22 11.2 1.3 2.0 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Tetraspannin PF00335.15 ETO12860.1 - 6.8 5.9 8.5 8.6 5.5 4.4 2.1 1 1 1 2 2 2 0 Tetraspanin family DUF912 PF06024.7 ETO12860.1 - 7.4 6.6 19.4 0.31 11.0 4.5 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ETRAMP PF09716.5 ETO12861.1 - 1 9.3 0.0 1 9.3 0.0 3.2 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Macoilin PF09726.4 ETO12861.1 - 3.2 5.9 20.8 4.1 5.5 14.4 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF1256 PF06866.6 ETO12862.1 - 0.021 14.0 0.0 0.029 13.5 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1256) DUF1841 PF08897.6 ETO12862.1 - 0.064 13.0 2.3 0.14 11.9 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1841) TEX13 PF15186.1 ETO12863.1 - 0.24 10.9 3.4 1.9 8.0 2.1 2.4 2 1 0 2 2 2 0 Testis-expressed sequence 13 protein family UxuA PF03786.8 ETO12864.1 - 2.1e-110 368.6 0.2 2.4e-110 368.3 0.2 1.0 1 0 0 1 1 1 1 D-mannonate dehydratase (UxuA) AP_endonuc_2 PF01261.19 ETO12864.1 - 0.00025 20.4 0.0 0.0016 17.7 0.0 2.1 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Pkinase PF00069.20 ETO12866.1 - 4.5e-33 114.5 0.0 4.5e-33 114.5 0.0 2.0 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO12866.1 - 8.5e-14 51.2 0.1 8.5e-14 51.2 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase DUF2371 PF10177.4 ETO12866.1 - 7.7 6.3 7.1 3.4 7.5 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) Metallophos PF00149.23 ETO12867.1 - 5e-21 75.0 0.0 1.3e-12 47.5 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Chalcone PF02431.10 ETO12868.1 - 0.11 11.9 0.1 3.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Chalcone-flavanone isomerase DUF2729 PF10870.3 ETO12869.1 - 1.5 8.6 4.5 0.36 10.5 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2729) Kelch_4 PF13418.1 ETO12870.1 - 1.7e-32 110.9 0.2 2.1e-10 40.1 0.0 4.2 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO12870.1 - 7.5e-30 102.4 0.1 7.3e-11 41.9 0.0 5.0 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO12870.1 - 1e-24 85.9 0.0 2.6e-06 27.2 0.0 4.3 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 ETO12870.1 - 1e-21 76.1 2.1 5e-07 29.6 0.0 4.3 3 1 1 4 4 4 3 Kelch motif Kelch_1 PF01344.20 ETO12870.1 - 2.1e-19 68.8 0.2 5.8e-05 22.5 0.0 4.3 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.10 ETO12870.1 - 5.1e-13 48.2 1.7 3.1e-06 26.7 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Rax2 PF12768.2 ETO12870.1 - 0.038 13.2 0.0 0.057 12.6 0.0 1.3 1 1 0 1 1 1 0 Cortical protein marker for cell polarity PQQ_3 PF13570.1 ETO12870.1 - 0.19 12.0 1.6 11 6.4 0.0 3.6 4 1 0 4 4 4 0 PQQ-like domain Herpes_gE PF02480.11 ETO12871.1 - 0.00025 19.4 0.3 0.00029 19.2 0.2 1.0 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DAG1 PF05454.6 ETO12871.1 - 0.00075 18.7 0.1 0.00089 18.5 0.0 1.1 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Shisa PF13908.1 ETO12871.1 - 0.0013 18.8 0.2 0.0017 18.5 0.1 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator TMEM154 PF15102.1 ETO12871.1 - 0.0055 16.4 0.1 0.011 15.4 0.0 1.5 1 1 0 1 1 1 1 TMEM154 protein family DUF1510 PF07423.6 ETO12871.1 - 0.017 14.5 5.2 0.02 14.2 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Vpu PF00558.14 ETO12871.1 - 0.02 14.4 0.7 0.03 13.8 0.2 1.6 1 1 1 2 2 2 0 Vpu protein DUF2681 PF10883.3 ETO12871.1 - 0.021 15.0 1.4 0.16 12.1 1.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) Flu_M2 PF00599.12 ETO12871.1 - 0.028 14.2 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Influenza Matrix protein (M2) YtpI PF14007.1 ETO12871.1 - 0.06 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 YtpI-like protein Orthoreo_P10 PF07204.6 ETO12871.1 - 0.061 13.0 0.1 0.096 12.4 0.1 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 DUF4134 PF13572.1 ETO12871.1 - 0.074 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4134) Adeno_E3_CR2 PF02439.10 ETO12871.1 - 0.084 12.4 3.2 0.15 11.6 2.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Thiolase_N PF00108.18 ETO12872.1 - 8.8e-65 218.3 0.0 1.2e-64 217.8 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 ETO12872.1 - 2e-38 130.5 0.0 4.8e-38 129.3 0.0 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 ETO12872.1 - 0.0048 16.8 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF2256 PF10013.4 ETO12872.1 - 0.1 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-H2C2_2 PF13465.1 ETO12873.1 - 2.2e-06 27.6 1.1 2.2e-06 27.6 0.8 3.0 2 1 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 ETO12873.1 - 5.7e-06 26.3 13.1 0.0019 18.4 0.1 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETO12873.1 - 4.7e-05 23.4 4.1 0.2 12.0 0.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 ETO12873.1 - 0.013 15.5 2.9 0.044 13.8 2.0 1.9 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 ETO12873.1 - 0.032 14.4 4.3 4 7.7 0.0 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 ETO12873.1 - 0.073 13.0 2.7 0.4 10.6 1.9 2.1 1 1 0 1 1 1 0 Zinc ribbon domain zf-C2H2_jaz PF12171.3 ETO12873.1 - 0.086 13.0 4.4 4.6 7.5 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 ETO12873.1 - 0.49 10.3 4.3 12 5.9 0.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-TRAF PF02176.13 ETO12873.1 - 0.75 10.2 4.8 0.69 10.3 0.3 2.6 3 0 0 3 3 3 0 TRAF-type zinc finger zf-BED PF02892.10 ETO12873.1 - 2 8.2 8.2 4.7 7.0 0.3 2.8 1 1 1 2 2 2 0 BED zinc finger zf-ribbon_3 PF13248.1 ETO12873.1 - 2.6 7.3 5.5 13 5.1 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain DNA_pol_B_exo1 PF03104.14 ETO12875.1 - 1.2e-06 27.6 0.5 2.8e-06 26.4 0.3 1.6 1 1 0 1 1 1 1 DNA polymerase family B, exonuclease domain PP2C_2 PF13672.1 ETO12876.1 - 0.23 10.8 1.4 0.26 10.6 0.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2C ALMT PF11744.3 ETO12876.1 - 1.3 7.6 5.1 1.4 7.4 3.5 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Prp18 PF02840.10 ETO12876.1 - 2.9 7.6 6.0 0.71 9.6 1.9 1.5 1 1 1 2 2 2 0 Prp18 domain DNA_primase_lrg PF04104.9 ETO12876.1 - 8 5.6 7.6 8.7 5.5 5.3 1.2 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit DUF2252 PF10009.4 ETO12876.1 - 8.4 5.1 7.9 8.7 5.1 5.5 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) TGF_beta_GS PF08515.7 ETO12880.1 - 0.26 10.6 0.1 0.26 10.6 0.1 1.8 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif DUF3959 PF13105.1 ETO12881.1 - 0.84 8.9 5.5 1.1 8.5 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) RPA_C PF08784.6 ETO12883.1 - 0.02 15.2 0.1 0.032 14.6 0.1 1.4 1 0 0 1 1 1 0 Replication protein A C terminal YusW PF14039.1 ETO12883.1 - 0.027 14.7 3.6 0.059 13.6 0.9 2.0 2 0 0 2 2 2 0 YusW-like protein PFK PF00365.15 ETO12883.1 - 0.18 10.7 0.4 0.29 10.0 0.3 1.3 1 0 0 1 1 1 0 Phosphofructokinase F-protein PF00469.15 ETO12883.1 - 0.26 10.6 3.7 0.3 10.4 2.5 1.2 1 1 0 1 1 1 0 Negative factor, (F-Protein) or Nef TMEM237 PF15383.1 ETO12884.1 - 0.00041 19.5 0.9 0.0005 19.2 0.7 1.1 1 0 0 1 1 1 1 Transmembrane protein 237 DUF853 PF05872.7 ETO12884.1 - 0.035 12.4 0.2 0.042 12.1 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Rrn6 PF10214.4 ETO12884.1 - 0.088 10.8 8.1 0.093 10.8 5.6 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Peptidase_S7 PF00949.16 ETO12884.1 - 0.5 9.7 4.9 5.4 6.4 3.1 2.0 1 1 1 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease CactinC_cactus PF09732.4 ETO12885.1 - 1.5e-51 173.2 9.5 1.5e-51 173.2 6.6 1.9 2 0 0 2 2 2 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.4 ETO12885.1 - 1.3e-17 63.6 12.6 1.3e-17 63.6 8.7 3.4 3 1 0 3 3 3 1 Conserved mid region of cactin Corona_nucleoca PF00937.13 ETO12885.1 - 0.84 8.5 34.3 0.15 11.0 14.6 2.8 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein Sipho_Gp157 PF05565.6 ETO12886.1 - 0.0096 15.5 1.6 0.011 15.3 1.1 1.0 1 0 0 1 1 1 1 Siphovirus Gp157 DnaI_N PF07319.6 ETO12886.1 - 0.2 11.9 1.7 0.49 10.6 0.6 1.8 1 1 1 2 2 2 0 Primosomal protein DnaI N-terminus DUF3436 PF11918.3 ETO12886.1 - 0.25 11.5 0.2 0.25 11.5 0.1 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3436) TPR_12 PF13424.1 ETO12887.1 - 1.1e-118 387.2 26.8 1e-21 76.6 0.4 7.1 3 3 5 8 8 8 8 Tetratricopeptide repeat TPR_11 PF13414.1 ETO12887.1 - 1.1e-46 156.2 28.9 6.4e-14 51.3 0.5 6.0 4 1 2 6 6 6 6 TPR repeat TPR_10 PF13374.1 ETO12887.1 - 6.2e-45 149.8 0.0 7e-06 25.8 0.0 10.1 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_1 PF00515.23 ETO12887.1 - 3.4e-43 143.5 43.5 5.2e-08 32.1 0.1 10.5 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.12 ETO12887.1 - 2.2e-40 133.3 37.3 1e-06 28.1 0.1 10.5 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_7 PF13176.1 ETO12887.1 - 4.7e-40 132.2 15.6 2.3e-06 26.9 0.0 10.3 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_8 PF13181.1 ETO12887.1 - 1.9e-35 117.9 52.1 1.1e-05 24.8 0.2 10.5 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_14 PF13428.1 ETO12887.1 - 1.2e-16 59.6 0.0 0.23 12.1 0.0 9.0 8 2 2 10 10 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO12887.1 - 1.3e-16 60.7 4.4 0.023 15.3 0.2 6.3 3 2 3 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO12887.1 - 2.8e-15 55.1 12.3 0.67 10.2 0.1 10.9 10 1 0 10 10 10 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO12887.1 - 7e-12 44.9 17.2 0.0064 16.8 0.1 8.3 9 0 0 9 9 8 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO12887.1 - 1.4e-11 44.3 23.1 0.00016 21.7 3.6 6.4 2 2 6 8 8 8 5 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 ETO12887.1 - 1.7e-08 34.1 37.9 0.27 11.1 0.1 8.9 8 1 1 9 9 9 3 MIT (microtubule interacting and transport) domain TPR_19 PF14559.1 ETO12887.1 - 6.3e-07 29.6 8.6 0.23 11.8 0.1 6.2 3 2 2 7 7 7 2 Tetratricopeptide repeat DUF2225 PF09986.4 ETO12887.1 - 4.1e-06 26.4 18.9 0.0004 19.9 3.2 4.3 3 2 2 5 5 5 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_21 PF09976.4 ETO12887.1 - 0.00032 20.6 2.1 0.13 12.1 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3856 PF12968.2 ETO12887.1 - 0.00036 20.3 7.0 0.0052 16.6 0.7 4.1 3 1 1 4 4 3 1 Domain of Unknown Function (DUF3856) Prefoldin PF02996.12 ETO12887.1 - 0.037 13.6 0.0 0.037 13.6 0.0 4.3 5 0 0 5 5 5 0 Prefoldin subunit TPR_9 PF13371.1 ETO12887.1 - 0.052 13.3 0.1 2.4 8.0 0.0 3.4 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_3 PF07720.7 ETO12887.1 - 0.1 12.3 29.3 0.093 12.5 0.3 7.5 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF3775 PF12616.3 ETO12887.1 - 0.11 12.2 0.0 14 5.5 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3775) Mob_Pre PF01076.14 ETO12887.1 - 3.6 7.1 26.1 3.3 7.3 0.0 5.9 5 2 1 6 6 6 0 Plasmid recombination enzyme Sel1 PF08238.7 ETO12887.1 - 4 8.2 29.9 0.51 11.0 0.3 7.4 10 0 0 10 10 6 0 Sel1 repeat ApoL PF05461.6 ETO12889.1 - 0.13 11.4 0.0 0.13 11.4 0.0 1.9 2 0 0 2 2 2 0 Apolipoprotein L DUF2749 PF10907.3 ETO12892.1 - 0.049 13.5 0.5 0.42 10.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) DUF1183 PF06682.7 ETO12892.1 - 0.7 9.4 11.8 0.29 10.6 6.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) DUF92 PF01940.11 ETO12892.1 - 1.2 8.2 7.6 9.5 5.2 0.0 2.8 3 0 0 3 3 3 0 Integral membrane protein DUF92 Gastrin PF00918.12 ETO12892.1 - 4.5 8.1 16.2 20 6.0 0.0 3.4 2 1 2 4 4 4 0 Gastrin/cholecystokinin family PRY PF13765.1 ETO12893.1 - 0.072 12.6 0.1 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 SPRY-associated domain PBP_sp32 PF07222.7 ETO12893.1 - 0.1 11.7 0.1 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 zf-C3HC4_2 PF13923.1 ETO12893.1 - 0.41 10.7 6.0 4.5 7.3 4.1 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TyeA PF09059.5 ETO12894.1 - 0.056 13.3 0.2 0.16 11.8 0.1 1.7 1 1 1 2 2 2 0 TyeA DUF4518 PF15008.1 ETO12895.1 - 0.0083 15.1 8.2 0.012 14.6 4.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4518) RRM_5 PF13893.1 ETO12895.1 - 0.071 12.9 0.1 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Suf PF05843.9 ETO12895.1 - 0.15 11.8 11.2 0.17 11.5 7.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Sec62 PF03839.11 ETO12895.1 - 1.4 8.3 8.8 1.9 7.8 6.1 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 FAM60A PF15396.1 ETO12895.1 - 4.2 7.0 9.4 5.1 6.7 6.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Zip PF02535.17 ETO12895.1 - 4.6 6.1 7.5 5.2 5.9 5.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Dicty_REP PF05086.7 ETO12895.1 - 6.3 4.4 9.9 7.6 4.1 6.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3464 PF11947.3 ETO12895.1 - 8.1 5.8 7.6 12 5.3 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DENN PF02141.16 ETO12897.1 - 1.3e-31 109.7 2.5 3.7e-25 88.7 0.6 2.4 2 0 0 2 2 2 2 DENN (AEX-3) domain uDENN PF03456.13 ETO12897.1 - 6.4e-16 58.0 0.2 8.5e-09 35.2 0.0 3.0 2 0 0 2 2 2 2 uDENN domain Tubulin PF00091.20 ETO12898.1 - 5.6e-34 117.8 1.2 2.9e-33 115.5 0.8 2.1 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO12898.1 - 3.3e-13 49.7 0.0 5.4e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Gly_kinase PF02595.10 ETO12898.1 - 0.0017 17.1 0.0 0.0025 16.5 0.0 1.1 1 0 0 1 1 1 1 Glycerate kinase family DcpS_C PF11969.3 ETO12899.1 - 5.8e-11 42.6 2.2 1.8e-10 41.0 1.5 1.8 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding TSGP1 PF07771.6 ETO12900.1 - 0.05 13.4 1.8 0.064 13.1 1.2 1.2 1 0 0 1 1 1 0 Tick salivary peptide group 1 Ribosomal_S25 PF03297.10 ETO12900.1 - 0.16 12.0 2.9 0.23 11.5 2.0 1.4 1 0 0 1 1 1 0 S25 ribosomal protein Astro_capsid PF03115.9 ETO12901.1 - 0.12 10.6 2.3 0.13 10.4 1.6 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor HEAT PF02985.17 ETO12902.1 - 0.0019 18.1 4.9 14 6.0 0.0 6.2 6 0 0 6 6 6 2 HEAT repeat Sporozoite_P67 PF05642.6 ETO12902.1 - 3.2 5.5 28.4 0.025 12.4 13.6 1.8 2 0 0 2 2 2 0 Sporozoite P67 surface antigen WD40 PF00400.27 ETO12904.1 - 2.2e-65 214.3 9.5 4.5e-13 48.5 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO12904.1 - 2.1e-09 37.3 0.0 0.0021 17.7 0.0 3.6 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO12904.1 - 2.1e-09 36.0 2.6 0.75 7.8 0.0 5.1 1 1 4 5 5 5 5 Nucleoporin Nup120/160 Nbas_N PF15492.1 ETO12904.1 - 6.2e-08 32.0 0.7 1.4 7.9 0.0 5.1 1 1 4 5 5 5 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 ETO12904.1 - 9.9e-07 28.2 7.5 0.77 9.4 0.0 5.6 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO12904.1 - 5.2e-06 24.9 0.3 0.017 13.4 0.0 3.0 2 1 0 3 3 3 2 Cytochrome D1 heme domain Resistin PF06954.6 ETO12904.1 - 0.00012 22.2 0.0 21 5.5 0.0 4.5 3 1 2 5 5 5 0 Resistin DPPIV_N PF00930.16 ETO12904.1 - 0.00027 19.6 0.0 1.7 7.1 0.0 3.9 2 2 2 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nucleoporin_N PF08801.6 ETO12904.1 - 0.00037 19.3 7.2 0.22 10.2 2.6 3.4 1 1 0 2 2 2 2 Nup133 N terminal like DUF1258 PF06869.7 ETO12904.1 - 0.00058 19.0 0.1 0.14 11.2 0.0 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1258) PQQ_2 PF13360.1 ETO12904.1 - 0.0015 18.0 0.0 0.0035 16.8 0.0 1.7 1 1 0 1 1 1 1 PQQ-like domain Ubiquitin_3 PF14836.1 ETO12904.1 - 0.0015 18.1 0.8 9.6 5.9 0.0 3.9 2 1 3 5 5 5 0 Ubiquitin-like domain FlgD_ig PF13860.1 ETO12904.1 - 0.039 13.6 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 FlgD Ig-like domain TFIIIC_delta PF12657.2 ETO12904.1 - 0.084 12.5 0.1 0.38 10.4 0.0 2.3 2 1 1 3 3 3 0 Transcription factor IIIC subunit delta N-term DUF3732 PF12532.3 ETO12904.1 - 0.095 12.2 0.1 48 3.4 0.0 3.9 2 1 4 6 6 6 0 Protein of unknown function (DUF3732) Inh PF02974.9 ETO12904.1 - 0.11 12.0 0.0 4.7 6.8 0.0 2.7 2 0 0 2 2 2 0 Protease inhibitor Inh Proteasome_A_N PF10584.4 ETO12904.1 - 8.8 5.7 12.4 47 3.4 0.0 5.0 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature CHAT PF12770.2 ETO12905.1 - 8.7e-12 44.7 0.1 1.2e-11 44.2 0.1 1.3 1 0 0 1 1 1 1 CHAT domain Peptidase_C25 PF01364.13 ETO12905.1 - 0.0011 18.0 0.0 0.0016 17.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C25 Peptidase_C14 PF00656.17 ETO12905.1 - 0.021 14.5 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Caspase domain Thiolase_N PF00108.18 ETO12907.1 - 7.3e-63 212.0 1.0 4.8e-40 137.2 0.0 2.8 2 1 0 2 2 2 2 Thiolase, N-terminal domain Thiolase_C PF02803.13 ETO12907.1 - 1.4e-42 144.0 0.4 3e-42 142.9 0.3 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 ETO12907.1 - 0.032 13.7 0.3 0.12 11.8 0.1 2.0 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain B56 PF01603.15 ETO12908.1 - 0.059 11.9 0.1 0.059 11.9 0.0 1.6 2 0 0 2 2 2 0 Protein phosphatase 2A regulatory B subunit (B56 family) KAT11 PF08214.6 ETO12908.1 - 0.16 11.0 3.1 0.17 10.9 2.1 1.0 1 0 0 1 1 1 0 Histone acetylation protein Ycf1 PF05758.7 ETO12908.1 - 0.42 8.2 6.2 0.43 8.2 4.3 1.0 1 0 0 1 1 1 0 Ycf1 Senescence PF06911.7 ETO12909.1 - 1.9e-13 50.5 13.6 1.7e-08 34.3 3.3 2.3 2 0 0 2 2 2 2 Senescence-associated protein CesA PF11439.3 ETO12910.1 - 0.19 11.6 2.2 0.25 11.3 0.4 2.0 1 1 1 2 2 2 0 Type III secretion system filament chaperone CesA Astro_capsid PF03115.9 ETO12910.1 - 1.2 7.3 3.8 1.1 7.3 2.6 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor VEFS-Box PF09733.4 ETO12910.1 - 2.3 7.8 7.0 0.23 11.1 0.2 2.2 1 1 1 2 2 2 0 VEFS-Box of polycomb protein Beta-lactamase PF00144.19 ETO12912.1 - 1.4e-23 83.5 0.0 1.1e-19 70.6 0.0 2.1 2 0 0 2 2 2 2 Beta-lactamase MIP-T3 PF10243.4 ETO12912.1 - 0.098 11.1 25.1 0.13 10.7 17.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 BUD22 PF09073.5 ETO12912.1 - 0.31 10.0 30.7 0.54 9.2 21.3 1.3 1 0 0 1 1 1 0 BUD22 Macoilin PF09726.4 ETO12912.1 - 0.51 8.5 28.8 0.64 8.2 20.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Hid1 PF12722.2 ETO12912.1 - 4.1 4.9 18.0 6.4 4.3 12.4 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF515 PF04415.7 ETO12912.1 - 8.9 4.4 27.2 15 3.7 18.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SprA-related PF12118.3 ETO12913.1 - 0.02 14.2 16.9 0.021 14.1 11.7 1.1 1 0 0 1 1 1 0 SprA-related family Nucleo_P87 PF07267.6 ETO12913.1 - 0.13 10.9 13.8 0.15 10.7 9.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PPP4R2 PF09184.6 ETO12913.1 - 0.27 10.7 27.1 0.35 10.3 18.8 1.1 1 0 0 1 1 1 0 PPP4R2 SRP-alpha_N PF04086.8 ETO12913.1 - 0.29 10.4 21.1 0.32 10.3 14.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Drc1-Sld2 PF11719.3 ETO12913.1 - 0.36 9.8 23.1 0.39 9.7 16.0 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein FLO_LFY PF01698.11 ETO12913.1 - 4.4 6.0 16.5 6.1 5.5 11.5 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein LtrA PF06772.6 ETO12914.1 - 4.1e-09 35.8 14.5 9.9e-09 34.5 9.7 1.7 1 1 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) DUF4449 PF14613.1 ETO12915.1 - 0.18 11.6 3.4 0.52 10.2 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4449) APG6 PF04111.7 ETO12916.1 - 0.00053 19.1 16.4 0.00053 19.1 11.4 3.8 3 1 0 3 3 2 2 Autophagy protein Apg6 Filament PF00038.16 ETO12916.1 - 0.0013 18.2 14.9 0.0013 18.2 10.4 3.9 3 1 0 3 3 3 2 Intermediate filament protein MbeD_MobD PF04899.7 ETO12916.1 - 0.0087 15.9 0.1 0.0087 15.9 0.1 5.3 4 3 0 4 4 3 1 MbeD/MobD like HrpB7 PF09486.5 ETO12916.1 - 0.056 13.3 0.3 0.056 13.3 0.2 4.3 4 1 0 4 4 4 0 Bacterial type III secretion protein (HrpB7) Myosin_tail_1 PF01576.14 ETO12916.1 - 0.07 10.8 44.8 0.0051 14.5 2.5 3.7 4 0 0 4 4 4 0 Myosin tail Baculo_PEP_C PF04513.7 ETO12916.1 - 0.22 11.3 20.6 6 6.6 0.0 4.4 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 ETO12916.1 - 0.28 10.7 62.9 0.15 11.6 13.9 4.9 3 2 1 4 4 4 0 IncA protein DUF1378 PF07125.6 ETO12916.1 - 0.31 11.0 8.0 5.8 6.9 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1378) Atg14 PF10186.4 ETO12916.1 - 0.64 8.9 48.7 1.3 7.9 2.2 3.3 3 0 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 IFT20 PF14931.1 ETO12916.1 - 0.73 9.7 41.9 0.051 13.4 8.9 5.2 5 0 0 5 5 5 0 Intraflagellar transport complex B, subunit 20 Reo_sigmaC PF04582.7 ETO12916.1 - 3 6.9 11.7 2.3 7.3 1.6 2.9 4 0 0 4 4 4 0 Reovirus sigma C capsid protein DUF869 PF05911.6 ETO12916.1 - 3.3 5.8 44.0 1.5e+04 -8.5 30.2 3.4 1 1 0 1 1 0 0 Plant protein of unknown function (DUF869) DUF3450 PF11932.3 ETO12916.1 - 7.6 5.7 44.0 2.1 7.5 2.6 4.5 4 1 0 4 4 4 0 Protein of unknown function (DUF3450) SAM_2 PF07647.12 ETO12917.1 - 0.12 12.2 1.1 0.21 11.4 0.0 1.9 2 1 1 3 3 3 0 SAM domain (Sterile alpha motif) RNF111_N PF15303.1 ETO12917.1 - 0.44 10.0 5.1 0.36 10.3 0.1 2.0 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase Arkadia N-terminus Sec3_C_2 PF15278.1 ETO12917.1 - 0.63 10.2 6.0 0.15 12.1 0.6 2.3 2 1 0 2 2 2 0 Sec3 exocyst complex subunit B56 PF01603.15 ETO12920.1 - 3.5e-130 434.3 8.1 3.9e-130 434.1 5.6 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) PI3_PI4_kinase PF00454.22 ETO12921.1 - 3.8e-31 108.3 0.1 4.2e-30 104.9 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 ETO12921.1 - 1.6e-11 43.7 0.1 4e-11 42.4 0.1 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.1 ETO12921.1 - 0.01 14.8 0.1 0.035 13.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) GAGE PF05831.6 ETO12922.1 - 8.7 6.5 10.2 0.37 10.9 1.2 2.7 3 1 0 3 3 3 0 GAGE protein DUF4407 PF14362.1 ETO12924.1 - 1.5 7.7 5.1 1.6 7.6 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MIP-T3 PF10243.4 ETO12924.1 - 4.8 5.5 26.7 6.1 5.1 18.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Herpes_env PF01673.13 ETO12924.1 - 5.5 5.4 7.9 7.2 5.0 5.5 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein TP53IP5 PF15331.1 ETO12924.1 - 7.3 6.4 11.7 11 5.8 8.1 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Rgp1 PF08737.5 ETO12927.1 - 1.2e-13 50.9 2.3 1.2e-13 50.9 1.6 2.8 2 1 1 3 3 3 1 Rgp1 Daxx PF03344.10 ETO12927.1 - 0.39 9.1 30.3 0.089 11.2 17.6 1.9 2 0 0 2 2 2 0 Daxx Family Prog_receptor PF02161.10 ETO12928.1 - 0.48 9.1 2.8 0.69 8.6 1.9 1.1 1 0 0 1 1 1 0 Progesterone receptor DUF3484 PF11983.3 ETO12928.1 - 0.64 10.8 9.4 0.2 12.5 3.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3484) BSP_II PF05432.6 ETO12928.1 - 1.4 8.1 15.2 2.6 7.2 10.5 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) G-alpha PF00503.15 ETO12929.1 - 3.4e-24 85.2 11.6 1.1e-21 77.0 8.0 2.1 1 1 0 1 1 1 1 G-protein alpha subunit Miro PF08477.8 ETO12929.1 - 0.00034 21.0 0.7 0.001 19.5 0.1 2.2 2 1 1 3 3 3 1 Miro-like protein Arf PF00025.16 ETO12929.1 - 0.0021 17.3 1.8 0.029 13.6 0.1 2.9 2 1 1 3 3 3 1 ADP-ribosylation factor family Arch_ATPase PF01637.13 ETO12929.1 - 0.0065 16.1 1.1 0.013 15.2 0.7 1.5 1 0 0 1 1 1 1 Archaeal ATPase PduV-EutP PF10662.4 ETO12929.1 - 0.01 15.3 0.6 0.03 13.8 0.2 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 ETO12929.1 - 0.02 14.5 1.6 0.13 11.8 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.1 ETO12929.1 - 0.034 14.0 1.0 0.057 13.3 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 ETO12929.1 - 0.069 13.1 0.1 0.16 11.9 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 ETO12929.1 - 0.074 12.5 0.1 0.38 10.1 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.1 ETO12929.1 - 0.095 12.8 0.5 0.41 10.7 0.3 2.2 1 1 0 1 1 1 0 AAA domain Protocadherin PF08374.6 ETO12929.1 - 3.4 7.2 9.3 4.9 6.7 1.6 2.4 2 0 0 2 2 2 0 Protocadherin Ead_Ea22 PF13935.1 ETO12929.1 - 5.5 7.3 8.0 41 4.5 3.1 2.4 1 1 1 2 2 2 0 Ead/Ea22-like protein Ribosomal_L24e PF01246.15 ETO12930.1 - 1.4e-17 63.2 1.6 1.4e-17 63.2 1.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e DUF3323 PF11796.3 ETO12930.1 - 0.41 9.9 5.4 3.8 6.7 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) Sigma_reg_N PF13800.1 ETO12932.1 - 0.0023 17.9 3.2 0.65 10.0 0.6 3.6 4 0 0 4 4 4 1 Sigma factor regulator N-terminal Gly-zipper_OmpA PF13436.1 ETO12932.1 - 0.023 14.3 0.3 0.048 13.3 0.2 1.5 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain YtzH PF14165.1 ETO12932.1 - 0.12 12.5 0.6 0.29 11.3 0.4 1.6 1 0 0 1 1 1 0 YtzH-like protein DUF241 PF03087.9 ETO12932.1 - 1.3 8.4 8.5 3.8 6.9 2.6 2.2 2 0 0 2 2 2 0 Arabidopsis protein of unknown function Pox_I5 PF04713.7 ETO12932.1 - 3.6 7.3 5.7 3 7.6 0.1 2.9 3 0 0 3 3 3 0 Poxvirus protein I5 Gly-zipper_OmpA PF13436.1 ETO12933.1 - 0.0055 16.3 24.5 0.07 12.7 2.8 2.6 1 1 1 2 2 2 2 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_YMGG PF13441.1 ETO12933.1 - 0.017 14.6 8.5 0.017 14.6 5.9 2.2 2 0 0 2 2 2 0 YMGG-like Gly-zipper Colicin PF01024.14 ETO12933.1 - 0.029 13.9 1.2 0.056 13.0 0.1 2.1 2 0 0 2 2 2 0 Colicin pore forming domain DUF2407_C PF13373.1 ETO12933.1 - 1.8 8.4 0.0 1.8 8.4 0.0 3.1 3 1 1 4 4 4 0 DUF2407 C-terminal domain Gly-zipper_Omp PF13488.1 ETO12933.1 - 7.7 6.2 46.6 0.19 11.4 11.7 2.3 1 1 1 2 2 2 0 Glycine zipper Sec20 PF03908.8 ETO12933.1 - 8.6 6.1 10.8 2.2 8.0 0.4 3.8 3 1 1 4 4 4 0 Sec20 MCM PF00493.18 ETO12934.1 - 0.0022 16.8 2.2 0.0062 15.3 1.3 1.9 2 1 0 2 2 2 1 MCM2/3/5 family MCPsignal PF00015.16 ETO12934.1 - 0.19 11.2 6.7 0.054 13.0 2.2 1.9 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Evr1_Alr PF04777.8 ETO12934.1 - 0.88 9.5 6.7 5.2 7.0 4.7 2.4 1 1 0 1 1 1 0 Erv1 / Alr family FTCD_C PF04961.7 ETO12934.1 - 4.5 6.6 8.8 0.25 10.7 0.4 3.0 3 1 1 4 4 4 0 Formiminotransferase-cyclodeaminase His_kinase PF06580.8 ETO12934.1 - 5.1 7.0 11.9 1.4 8.8 0.1 4.1 3 2 0 3 3 3 0 Histidine kinase Nucleoside_tran PF01733.13 ETO12935.1 - 0.01 15.0 0.1 0.016 14.3 0.1 1.3 1 0 0 1 1 1 0 Nucleoside transporter IncA PF04156.9 ETO12935.1 - 0.048 13.2 4.6 0.63 9.6 3.4 2.1 1 1 0 1 1 1 0 IncA protein FAM176 PF14851.1 ETO12935.1 - 0.048 13.3 0.3 0.087 12.5 0.2 1.4 1 0 0 1 1 1 0 FAM176 family Bap31 PF05529.7 ETO12935.1 - 0.074 12.5 2.6 0.13 11.7 1.8 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Uds1 PF15456.1 ETO12935.1 - 0.73 9.8 5.9 2.6 8.0 2.6 2.3 2 0 0 2 2 2 0 Up-regulated During Septation ETRAMP PF09716.5 ETO12935.1 - 0.98 9.4 6.8 3.1 7.8 4.7 1.9 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) IFT20 PF14931.1 ETO12935.1 - 1.6 8.6 8.1 3 7.7 2.5 2.6 3 0 0 3 3 3 0 Intraflagellar transport complex B, subunit 20 CDC27 PF09507.5 ETO12936.1 - 0.013 14.7 4.4 0.013 14.7 3.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2052 PF09747.4 ETO12936.1 - 0.032 14.1 7.4 0.038 13.9 5.1 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) tRNA-Thr_ED PF08915.6 ETO12936.1 - 0.12 12.3 0.2 0.15 12.0 0.1 1.1 1 0 0 1 1 1 0 Archaea-specific editing domain of threonyl-tRNA synthetase Neur_chan_memb PF02932.11 ETO12936.1 - 0.59 9.9 2.4 0.66 9.8 1.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Lipase_chap PF03280.9 ETO12936.1 - 0.71 9.3 9.8 1 8.8 6.7 1.3 1 1 0 1 1 1 0 Proteobacterial lipase chaperone protein Nucleoporin2 PF04096.9 ETO12936.1 - 0.85 9.4 3.8 1 9.2 0.2 2.2 1 1 0 2 2 2 0 Nucleoporin autopeptidase IncA PF04156.9 ETO12936.1 - 1.1 8.7 8.9 1.6 8.3 6.2 1.3 1 0 0 1 1 1 0 IncA protein DUF3288 PF11691.3 ETO12938.1 - 0.34 10.6 3.8 0.4 10.4 0.4 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3288) Allexi_40kDa PF05549.6 ETO12938.1 - 1.5 8.0 7.6 0.23 10.7 1.6 1.8 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF3810 PF12725.2 ETO12938.1 - 2.7 6.8 7.1 1.9 7.3 1.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) Laminin_II PF06009.7 ETO12938.1 - 3.2 7.5 8.6 11 5.7 1.1 2.7 1 1 0 2 2 2 0 Laminin Domain II IncA PF04156.9 ETO12938.1 - 8.1 5.9 15.5 16 5.0 0.9 2.1 1 1 1 2 2 2 0 IncA protein IncA PF04156.9 ETO12939.1 - 3.3e-07 30.1 1.4 3.3e-07 30.1 1.0 2.0 2 1 0 2 2 2 1 IncA protein Gly-zipper_OmpA PF13436.1 ETO12939.1 - 0.0052 16.4 4.0 0.0082 15.7 2.8 1.3 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain DUF726 PF05277.7 ETO12939.1 - 0.016 14.1 0.7 0.018 13.9 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF726) WEMBL PF05701.6 ETO12939.1 - 0.021 13.3 3.8 0.035 12.5 2.6 1.3 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF1154 PF06631.6 ETO12939.1 - 0.25 11.0 0.0 0.25 11.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1154) PhoU PF01895.14 ETO12939.1 - 0.32 11.4 3.0 1.8 9.0 1.7 2.4 2 1 0 2 2 2 0 PhoU domain DUF1049 PF06305.6 ETO12939.1 - 6.7 6.2 7.4 80 2.8 1.2 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1049) WD40 PF00400.27 ETO12942.1 - 0.0002 21.1 0.0 0.0051 16.6 0.0 2.7 3 0 0 3 3 3 1 WD domain, G-beta repeat Nbas_N PF15492.1 ETO12942.1 - 0.0061 15.6 0.1 0.014 14.4 0.0 1.6 2 0 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal Hira PF07569.6 ETO12942.1 - 0.092 11.9 0.1 0.77 8.9 0.0 2.1 2 0 0 2 2 2 0 TUP1-like enhancer of split WD40 PF00400.27 ETO12943.1 - 1.6e-52 173.6 22.2 4.6e-12 45.3 0.2 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO12943.1 - 4.6e-10 38.2 5.5 0.0055 14.9 0.0 5.3 2 2 3 5 5 5 4 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO12943.1 - 0.0099 15.6 2.2 0.078 12.7 0.1 3.3 1 1 4 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Kinesin PF00225.18 ETO12944.1 - 1.6e-47 161.8 1.9 2.5e-47 161.2 1.3 1.2 1 0 0 1 1 1 1 Kinesin motor domain bZIP_2 PF07716.10 ETO12944.1 - 0.044 13.5 5.7 0.14 12.0 3.9 1.9 1 1 0 1 1 1 0 Basic region leucine zipper DUF837 PF05769.6 ETO12944.1 - 0.046 13.2 0.5 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF837) Ribosomal_L29 PF00831.18 ETO12944.1 - 0.37 10.5 4.9 0.78 9.4 0.7 2.8 2 1 0 2 2 2 0 Ribosomal L29 protein Metallophos_2 PF12850.2 ETO12945.1 - 2.5e-06 27.4 0.0 4.8e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 ETO12945.1 - 0.0029 17.0 0.6 0.0046 16.3 0.4 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase zf-RanBP PF00641.13 ETO12947.1 - 0.0019 17.2 1.9 0.0033 16.4 1.3 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-ribbon_3 PF13248.1 ETO12947.1 - 0.0024 17.0 1.9 0.0041 16.2 1.3 1.4 1 0 0 1 1 1 1 zinc-ribbon domain CENP-B_dimeris PF09026.5 ETO12947.1 - 0.003 17.7 3.4 0.005 17.0 2.3 1.3 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Pox_G5 PF04599.7 ETO12947.1 - 0.0035 16.0 2.5 0.0041 15.8 1.8 1.1 1 0 0 1 1 1 1 Poxvirus G5 protein Cript PF10235.4 ETO12947.1 - 0.014 15.7 1.0 0.014 15.7 0.7 2.4 3 1 0 3 3 3 0 Microtubule-associated protein CRIPT Baculo_ME53 PF06061.6 ETO12947.1 - 0.016 14.2 1.6 0.028 13.4 1.1 1.4 1 0 0 1 1 1 0 Baculoviridae ME53 DZR PF12773.2 ETO12947.1 - 0.026 14.3 0.7 0.049 13.4 0.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon PHF5 PF03660.9 ETO12947.1 - 0.075 13.0 0.1 0.17 11.9 0.1 1.6 2 0 0 2 2 2 0 PHF5-like protein Atrophin-1 PF03154.10 ETO12947.1 - 0.12 10.4 4.1 0.15 10.1 2.9 1.1 1 0 0 1 1 1 0 Atrophin-1 family FAM176 PF14851.1 ETO12947.1 - 0.16 11.6 1.8 0.29 10.7 1.2 1.4 1 0 0 1 1 1 0 FAM176 family fn3 PF00041.16 ETO12948.1 - 4.5e-09 36.3 0.5 1.2e-05 25.3 0.0 3.0 3 0 0 3 3 3 2 Fibronectin type III domain CDC45 PF02724.9 ETO12948.1 - 0.021 12.9 11.1 0.022 12.8 7.7 1.0 1 0 0 1 1 1 0 CDC45-like protein FLO_LFY PF01698.11 ETO12948.1 - 0.082 11.7 8.3 0.13 11.1 5.8 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Dsh_C PF12316.3 ETO12948.1 - 0.14 12.2 5.8 0.17 12.0 4.0 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal FAM176 PF14851.1 ETO12948.1 - 0.15 11.7 8.0 0.21 11.2 5.5 1.3 1 0 0 1 1 1 0 FAM176 family GEMIN8 PF15348.1 ETO12948.1 - 0.25 11.3 10.1 0.41 10.6 7.0 1.4 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DUF2151 PF10221.4 ETO12948.1 - 0.47 8.5 8.4 0.51 8.4 5.8 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Serinc PF03348.10 ETO12948.1 - 0.52 8.9 2.5 0.59 8.7 1.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Trypan_PARP PF05887.6 ETO12948.1 - 0.53 10.1 4.8 0.71 9.6 3.3 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) EBV-NA3 PF05009.7 ETO12948.1 - 0.53 9.4 3.3 0.7 9.1 2.3 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) RXT2_N PF08595.6 ETO12948.1 - 0.59 9.9 7.8 0.98 9.2 5.4 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_phi PF04931.8 ETO12948.1 - 0.83 7.3 14.6 1.1 7.0 10.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi POX PF07526.6 ETO12948.1 - 0.91 9.7 7.5 1.3 9.2 5.2 1.4 1 0 0 1 1 1 0 Associated with HOX U79_P34 PF03064.11 ETO12948.1 - 1 8.8 16.4 1.3 8.4 11.3 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF3827 PF12877.2 ETO12948.1 - 1.2 7.1 9.6 1.4 6.9 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Nop14 PF04147.7 ETO12948.1 - 1.3 6.8 17.0 1.4 6.7 11.8 1.0 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 ETO12948.1 - 3.3 7.2 16.1 6 6.4 11.2 1.5 1 1 0 1 1 1 0 Sigma-70, non-essential region Hid1 PF12722.2 ETO12948.1 - 5.5 4.5 11.0 6.5 4.3 7.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3824 PF12868.2 ETO12948.1 - 6.7 7.6 10.7 3.4 8.6 6.0 1.6 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) TRAP_alpha PF03896.11 ETO12948.1 - 7.5 5.4 7.9 9.4 5.1 5.5 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NPR3 PF03666.8 ETO12948.1 - 8.3 4.8 13.0 10 4.4 9.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 NARP1 PF12569.3 ETO12948.1 - 9.7 4.8 14.1 11 4.5 9.7 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DivIC PF04977.10 ETO12949.1 - 0.0049 16.3 0.3 0.0049 16.3 0.2 2.2 2 0 0 2 2 2 1 Septum formation initiator Mnd1 PF03962.10 ETO12949.1 - 0.014 15.0 5.9 0.11 12.0 1.7 2.1 2 0 0 2 2 2 0 Mnd1 family HemX PF04375.9 ETO12949.1 - 0.077 11.5 3.6 0.97 7.9 0.2 2.1 2 0 0 2 2 2 0 HemX Bap31 PF05529.7 ETO12949.1 - 0.086 12.2 1.5 0.25 10.7 0.0 2.1 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like SlyX PF04102.7 ETO12949.1 - 0.1 12.9 2.9 0.15 12.4 0.6 2.3 3 0 0 3 3 3 0 SlyX Flagellin_C PF00700.16 ETO12949.1 - 0.25 11.5 2.2 1.5 8.9 0.0 3.0 3 0 0 3 3 3 0 Bacterial flagellin C-terminal helical region Muted PF14942.1 ETO12949.1 - 0.56 10.0 7.5 0.16 11.8 1.5 2.3 2 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein Tropomyosin_1 PF12718.2 ETO12949.1 - 1.2 8.9 4.8 2.5 7.9 0.2 2.4 2 1 0 2 2 2 0 Tropomyosin like Ribosomal_L19e PF01280.15 ETO12950.1 - 1e-30 106.4 15.3 1e-30 106.4 10.6 3.0 2 1 0 2 2 2 1 Ribosomal protein L19e GAGA_bind PF06217.7 ETO12950.1 - 0.83 9.5 12.6 1.8 8.4 8.7 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family DUF1675 PF07897.6 ETO12950.1 - 2.9 7.7 12.7 4.9 6.9 8.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF3552 PF12072.3 ETO12950.1 - 3.6 6.7 22.7 1.8 7.6 14.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Peptidase_S49_N PF08496.5 ETO12951.1 - 0.14 11.9 0.8 0.18 11.5 0.6 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal LSM PF01423.17 ETO12953.1 - 1.1e-19 69.7 0.0 1.4e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain MMS22L_C PF14911.1 ETO12953.1 - 0.046 12.7 0.0 0.054 12.5 0.0 1.0 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal Ras PF00071.17 ETO12954.1 - 1.3e-48 164.4 1.6 3.8e-24 84.9 0.0 2.2 1 1 1 2 2 2 2 Ras family Miro PF08477.8 ETO12954.1 - 7.1e-12 45.8 1.1 1.3e-09 38.6 0.0 2.8 2 2 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO12954.1 - 2.7e-10 39.7 0.9 2.9e-06 26.6 0.0 2.2 1 1 1 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETO12954.1 - 3.4e-05 23.7 0.0 0.00018 21.4 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 ETO12954.1 - 0.00026 20.2 2.1 0.028 13.6 0.0 2.1 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 ETO12954.1 - 0.00034 19.8 0.1 0.00096 18.3 0.0 1.7 1 1 1 2 2 2 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 ETO12954.1 - 0.015 14.7 0.1 0.48 9.8 0.1 2.5 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Arch_ATPase PF01637.13 ETO12954.1 - 0.026 14.2 0.6 0.061 13.0 0.1 1.7 1 1 1 2 2 2 0 Archaeal ATPase AAA_14 PF13173.1 ETO12954.1 - 0.039 13.8 0.8 0.078 12.8 0.2 1.7 2 0 0 2 2 2 0 AAA domain PRK PF00485.13 ETO12954.1 - 0.077 12.5 0.0 0.15 11.6 0.0 1.4 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.1 ETO12954.1 - 0.13 12.2 0.0 0.63 10.0 0.0 1.7 1 1 1 2 2 2 0 AAA ATPase domain ArfGap PF01412.13 ETO12955.1 - 1.1e-12 47.7 0.1 4.7e-12 45.7 0.0 2.1 1 1 0 1 1 1 1 Putative GTPase activating protein for Arf RasGAP_C PF03836.10 ETO12957.1 - 6.6e-07 29.1 7.2 0.00022 20.9 5.0 2.2 1 1 0 1 1 1 1 RasGAP C-terminus DUF2408 PF10303.4 ETO12957.1 - 0.15 12.1 3.8 1 9.5 2.5 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) PAP_RNA-bind PF04926.10 ETO12957.1 - 0.5 9.8 8.7 0.96 8.9 5.5 1.7 1 1 0 2 2 2 0 Poly(A) polymerase predicted RNA binding domain Phage_Integr_2 PF13009.1 ETO12957.1 - 1.1 8.0 11.9 7.1 5.4 0.1 2.0 1 1 1 2 2 2 0 Putative phage integrase WD40 PF00400.27 ETO12958.1 - 1e-51 171.0 16.8 1.2e-11 43.9 0.3 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO12958.1 - 3.3e-07 28.9 1.9 7.8e-06 24.4 0.2 2.6 1 1 1 3 3 3 1 Cytochrome D1 heme domain Nup160 PF11715.3 ETO12958.1 - 0.00028 19.1 1.0 0.021 12.9 0.1 3.3 2 2 0 2 2 2 1 Nucleoporin Nup120/160 PD40 PF07676.7 ETO12958.1 - 0.011 15.3 4.5 3.8 7.2 0.0 4.6 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Tox-PL PF15644.1 ETO12958.1 - 0.093 13.4 0.0 3 8.5 0.0 3.0 3 1 0 3 3 3 0 Papain fold toxin 1 AgrB PF04647.10 ETO12959.1 - 0.55 9.2 7.1 0.2 10.7 0.9 2.6 2 1 1 3 3 3 0 Accessory gene regulator B Ras PF00071.17 ETO12960.1 - 2.4e-05 23.7 0.2 0.021 14.1 0.0 2.5 2 0 0 2 2 2 2 Ras family PI31_Prot_N PF11566.3 ETO12961.1 - 4.4e-09 36.1 8.4 1.1e-08 34.7 0.1 2.7 3 0 0 3 3 3 2 PI31 proteasome regulator N-terminal OAD_gamma PF04277.8 ETO12961.1 - 0.48 10.8 2.9 16 5.9 0.3 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain HEAT PF02985.17 ETO12963.1 - 0.024 14.7 0.2 12 6.2 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat PNPase PF03726.9 ETO12963.1 - 0.081 13.2 2.1 0.22 11.7 1.4 1.8 1 0 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain HEAT_2 PF13646.1 ETO12963.1 - 0.1 12.9 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 HEAT repeats Corona_NS2 PF04753.7 ETO12965.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Coronavirus non-structural protein NS2 CAF-1_p150 PF11600.3 ETO12965.1 - 6.9 5.9 51.9 4.2 6.7 4.6 2.6 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Laminin_G_3 PF13385.1 ETO12966.1 - 5.9e-09 36.3 0.0 1.3e-08 35.2 0.0 1.6 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Peptidase_S49_N PF08496.5 ETO12966.1 - 2.7 7.7 6.9 1.4 8.6 1.8 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Menin PF05053.8 ETO12967.1 - 0.29 9.2 8.1 0.38 8.8 5.6 1.1 1 0 0 1 1 1 0 Menin BUD22 PF09073.5 ETO12967.1 - 0.79 8.7 16.8 1.1 8.2 11.6 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.9 ETO12967.1 - 2.1 6.2 7.2 3 5.7 5.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 ETO12967.1 - 5.5 5.3 17.0 7.3 4.9 11.8 1.1 1 0 0 1 1 1 0 Daxx Family Mannosyl_trans PF05007.8 ETO12968.1 - 2.4e-39 135.5 45.1 1e-38 133.5 31.3 2.0 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) TFIIS_C PF01096.13 ETO12969.1 - 4.7e-12 45.3 2.3 4.7e-12 45.3 1.6 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 ETO12969.1 - 0.0016 18.1 9.4 0.0082 15.8 2.0 3.3 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit C1_1 PF00130.17 ETO12969.1 - 0.0054 16.4 3.1 0.0054 16.4 2.1 2.3 2 1 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Rpr2 PF04032.11 ETO12969.1 - 0.018 14.9 1.2 0.018 14.9 0.8 2.8 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain SpoIIIAH PF12685.2 ETO12969.1 - 0.023 14.2 4.9 0.031 13.7 3.4 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein DZR PF12773.2 ETO12969.1 - 0.13 12.1 12.1 0.059 13.1 2.0 2.5 2 1 0 2 2 2 0 Double zinc ribbon HypA PF01155.14 ETO12969.1 - 0.24 11.0 5.7 3.4 7.3 1.7 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family TF_Zn_Ribbon PF08271.7 ETO12969.1 - 0.53 9.6 6.2 0.52 9.6 0.6 2.7 3 0 0 3 3 3 0 TFIIB zinc-binding Zn_Tnp_IS91 PF14319.1 ETO12969.1 - 0.55 9.7 13.2 0.092 12.2 1.6 2.8 2 1 0 2 2 2 0 Transposase zinc-binding domain DUF2072 PF09845.4 ETO12969.1 - 0.58 10.0 14.3 7.2 6.5 0.1 2.7 1 1 1 2 2 2 0 Zn-ribbon containing protein (DUF2072) Zn_Tnp_IS1595 PF12760.2 ETO12969.1 - 0.98 9.2 8.6 8.7 6.2 2.2 3.0 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Cytochrome-c551 PF10643.4 ETO12969.1 - 1.4 8.1 3.8 0.79 8.9 1.1 1.7 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 Auto_anti-p27 PF06677.7 ETO12969.1 - 1.9 8.3 6.5 1.7 8.4 0.0 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-C4_ClpX PF06689.8 ETO12969.1 - 4.4 6.9 11.1 0.47 10.0 1.1 2.9 3 0 0 3 3 3 0 ClpX C4-type zinc finger Rubredoxin PF00301.15 ETO12969.1 - 7.7 6.4 7.5 37 4.3 0.1 3.4 3 0 0 3 3 3 0 Rubredoxin Abhydrolase_2 PF02230.11 ETO12970.1 - 1.6e-36 125.8 0.0 1.9e-36 125.5 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.8 ETO12970.1 - 2.3e-07 30.4 0.0 1.1e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 ETO12970.1 - 2e-06 27.6 0.0 2.9e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 ETO12970.1 - 0.015 14.9 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETO12970.1 - 0.046 13.5 0.1 0.36 10.6 0.1 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family Imm27 PF15573.1 ETO12971.1 - 0.037 13.2 0.3 0.046 12.9 0.2 1.1 1 0 0 1 1 1 0 Immunity protein 27 Cytochrom_B561 PF03188.11 ETO12972.1 - 0.0016 18.2 10.3 0.058 13.2 0.4 2.3 1 1 1 2 2 2 2 Eukaryotic cytochrome b561 Nodulin-like PF06813.8 ETO12972.1 - 0.013 14.8 2.3 0.055 12.7 1.6 1.9 1 1 0 1 1 1 0 Nodulin-like YtpI PF14007.1 ETO12972.1 - 0.017 15.0 3.4 1.5 8.7 0.1 2.5 3 0 0 3 3 3 0 YtpI-like protein DUF3754 PF12576.3 ETO12972.1 - 0.032 13.8 3.4 1.9 8.1 0.2 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3754) DUF1616 PF07760.6 ETO12972.1 - 0.032 13.3 1.5 0.033 13.3 1.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) DUF898 PF05987.8 ETO12972.1 - 0.037 12.9 2.3 0.042 12.7 1.6 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Cytochrom_B_N PF00033.14 ETO12972.1 - 0.045 13.0 2.7 0.11 11.8 1.9 1.8 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB DUF973 PF06157.6 ETO12972.1 - 0.057 12.3 4.4 0.065 12.1 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF4405 PF14358.1 ETO12972.1 - 0.071 13.2 2.6 3.8 7.7 0.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4405) Ni_hydr_CYTB PF01292.15 ETO12972.1 - 0.29 10.5 3.2 1.5 8.1 2.2 2.0 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 DUF3487 PF11990.3 ETO12972.1 - 0.5 9.7 2.1 1.2 8.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) DUF1673 PF07895.6 ETO12972.1 - 1.3 8.5 6.0 1.7 8.1 4.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) DUF202 PF02656.10 ETO12972.1 - 1.9 8.7 7.3 91 3.3 4.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF4282 PF14110.1 ETO12972.1 - 3.7 7.8 8.4 12 6.1 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) zf-DHHC PF01529.15 ETO12972.1 - 5.6 6.3 6.9 11 5.3 1.6 2.1 1 1 1 2 2 2 0 DHHC palmitoyltransferase Claudin_2 PF13903.1 ETO12972.1 - 6.8 6.3 15.7 0.81 9.3 3.5 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction SdpI PF13630.1 ETO12972.1 - 9.2 6.0 11.7 1.1 9.0 1.6 2.2 2 0 0 2 2 2 0 SdpI/YhfL protein family 2OG-FeII_Oxy_3 PF13640.1 ETO12974.1 - 8.1e-14 51.9 0.0 1.4e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 ETO12974.1 - 0.00033 20.2 0.5 0.00087 18.8 0.4 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Phlebovirus_NSM PF07246.6 ETO12974.1 - 0.01 15.0 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF4313 PF14190.1 ETO12974.1 - 0.015 14.9 0.3 0.033 13.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4313) SDA1 PF05285.7 ETO12976.1 - 0.14 11.3 18.1 0.17 11.1 12.5 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 ETO12976.1 - 0.44 8.3 19.8 0.46 8.3 13.7 1.0 1 0 0 1 1 1 0 Nop14-like family eIF-3c_N PF05470.7 ETO12976.1 - 1.2 7.1 9.8 1.4 6.9 6.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Lin-8 PF03353.10 ETO12976.1 - 1.4 8.1 7.9 1.4 8.1 5.5 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Daxx PF03344.10 ETO12976.1 - 2.1 6.7 20.1 2.2 6.6 14.0 1.0 1 0 0 1 1 1 0 Daxx Family CENP-T PF15511.1 ETO12976.1 - 2.3 7.3 13.0 2.5 7.2 9.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Phosphoprotein PF00922.12 ETO12976.1 - 5.9 6.0 11.5 6.5 5.8 8.0 1.1 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein CDC45 PF02724.9 ETO12976.1 - 9.6 4.0 11.9 10 4.0 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein ubiquitin PF00240.18 ETO12978.1 - 0.0047 16.3 0.4 0.026 13.8 0.3 2.1 1 1 0 1 1 1 1 Ubiquitin family Med3 PF11593.3 ETO12980.1 - 0.0099 15.1 12.7 0.015 14.5 8.8 1.3 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal RAB3GAP2_N PF14655.1 ETO12980.1 - 0.074 12.0 5.2 0.097 11.6 3.6 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF775 PF05603.7 ETO12980.1 - 0.23 10.9 6.9 0.34 10.4 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF775) BAF1_ABF1 PF04684.8 ETO12980.1 - 0.35 9.6 16.0 0.45 9.2 11.1 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Fil_haemagg_2 PF13332.1 ETO12981.1 - 0.00021 21.0 34.8 0.032 13.9 0.6 5.6 2 2 3 5 5 5 3 Haemagluttinin repeat Amino_oxidase PF01593.19 ETO12982.1 - 0.0051 15.9 0.1 0.5 9.3 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Nucleoplasmin PF03066.10 ETO12983.1 - 0.012 15.1 9.9 0.012 15.1 6.8 3.9 2 1 1 3 3 3 0 Nucleoplasmin Bromodomain PF00439.20 ETO12984.1 - 0.0014 18.4 3.0 0.93 9.4 0.1 3.3 2 1 1 3 3 3 2 Bromodomain TrbC PF04956.8 ETO12985.1 - 0.24 11.4 0.1 0.24 11.4 0.1 3.4 3 1 1 4 4 4 0 TrbC/VIRB2 family DUF373 PF04123.8 ETO12985.1 - 6.1 5.7 14.4 1.5 7.7 1.1 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF373) Orai-1 PF07856.7 ETO12985.1 - 6.9 6.1 11.4 25 4.3 7.2 2.5 1 1 0 2 2 2 0 Mediator of CRAC channel activity SPATA24 PF15175.1 ETO12986.1 - 0.019 14.6 10.6 0.026 14.2 7.3 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 IpaD PF06511.6 ETO12986.1 - 0.13 11.2 3.8 0.14 11.1 2.7 1.1 1 0 0 1 1 1 0 Invasion plasmid antigen IpaD DUF802 PF05650.6 ETO12986.1 - 0.23 11.6 0.3 0.23 11.6 0.2 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF802) IncA PF04156.9 ETO12986.1 - 1.2 8.7 13.4 1.5 8.3 9.3 1.1 1 0 0 1 1 1 0 IncA protein Vps39_1 PF10366.4 ETO12986.1 - 1.8 8.6 8.3 2.2 8.3 2.0 2.3 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 1 PRP1_N PF06424.7 ETO12986.1 - 2.9 8.2 6.7 3.4 8.0 4.6 1.4 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal Bravo_FIGEY PF13882.1 ETO12986.1 - 3 8.8 5.7 2 9.3 2.1 1.8 1 1 1 2 2 2 0 Bravo-like intracellular region Adaptin_binding PF10199.4 ETO12986.1 - 3.5 7.9 8.4 2.2 8.5 4.6 1.5 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Spc7 PF08317.6 ETO12986.1 - 4.3 5.8 14.8 5.9 5.4 10.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FlaC_arch PF05377.6 ETO12986.1 - 5.9 6.8 9.4 14 5.6 0.4 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Spc7 PF08317.6 ETO12987.1 - 3.9 6.0 46.2 0.012 14.3 11.9 2.9 1 1 3 4 4 4 0 Spc7 kinetochore protein Mod_r PF07200.8 ETO12987.1 - 4.5 7.1 54.0 3.4 7.5 4.4 4.7 1 1 4 5 5 5 0 Modifier of rudimentary (Mod(r)) protein Mnd1 PF03962.10 ETO12987.1 - 4.7 6.8 49.8 0.89 9.1 3.2 3.3 1 1 2 3 3 3 0 Mnd1 family DUF1493 PF07377.7 ETO12988.1 - 0.046 13.8 0.3 0.1 12.7 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1493) Pkinase PF00069.20 ETO12989.1 - 4.7e-10 39.0 0.0 4.7e-10 39.0 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO12989.1 - 6.5e-05 22.1 0.0 0.00012 21.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Mem_trans PF03547.13 ETO12989.1 - 0.29 9.3 1.8 0.32 9.2 1.3 1.3 1 0 0 1 1 1 0 Membrane transport protein Hex_IIIa PF02455.11 ETO12989.1 - 1.6 7.3 14.8 1.8 7.1 10.3 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Macoilin PF09726.4 ETO12989.1 - 3.9 5.6 25.0 4.3 5.4 17.3 1.0 1 0 0 1 1 1 0 Transmembrane protein TFIIA PF03153.8 ETO12989.1 - 7.3 6.3 42.0 8.4 6.1 29.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAP1 PF08601.5 ETO12989.1 - 7.7 6.0 28.7 11 5.5 19.9 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Rib_5-P_isom_A PF06026.9 ETO12990.1 - 9.3e-47 158.5 0.0 1.2e-46 158.1 0.0 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 ETO12990.1 - 0.018 14.7 1.1 0.19 11.3 0.2 2.3 1 1 1 2 2 2 0 DeoR C terminal sensor domain Tudor-knot PF11717.3 ETO12992.1 - 3.6e-05 23.3 0.1 6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain PBP1_TM PF14812.1 ETO12992.1 - 0.21 11.9 2.6 0.46 10.8 1.8 1.7 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Apc15p PF05841.6 ETO12992.1 - 0.73 10.5 5.2 0.96 10.1 3.6 1.1 1 0 0 1 1 1 0 Apc15p protein DUF912 PF06024.7 ETO12993.1 - 0.14 12.1 0.0 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) BCIP PF13862.1 ETO12993.1 - 0.47 9.9 4.1 0.21 11.0 1.1 1.6 2 0 0 2 2 2 0 p21-C-terminal region-binding protein TPP_enzyme_C PF02775.16 ETO12994.1 - 1.2e-21 76.8 0.1 2e-21 76.2 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain UPF0093 PF03653.8 ETO12995.1 - 0.0006 19.7 1.5 0.00096 19.1 1.1 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0093) DUF791 PF05631.9 ETO12995.1 - 0.016 13.9 0.2 0.031 12.9 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF791) DUF4135 PF13575.1 ETO12995.1 - 0.078 11.9 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) DUF791 PF05631.9 ETO12996.1 - 1.5e-34 119.2 3.1 3.3e-26 91.8 0.8 2.0 1 1 0 2 2 2 2 Protein of unknown function (DUF791) TMEM213 PF15192.1 ETO12996.1 - 0.013 15.4 0.2 0.032 14.2 0.2 1.6 1 0 0 1 1 1 0 TMEM213 family Pkinase PF00069.20 ETO12997.1 - 8.7e-26 90.6 0.2 1.4e-25 89.9 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO12997.1 - 0.0035 16.4 0.0 0.0082 15.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase DUF2608 PF11019.3 ETO12997.1 - 0.01 14.8 0.7 0.01 14.8 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) Sial-lect-inser PF09264.5 ETO12997.1 - 0.094 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Vibrio cholerae sialidase, lectin insertion GST_C_3 PF14497.1 ETO12999.1 - 9.7e-06 25.9 0.1 3e-05 24.4 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 ETO12999.1 - 0.00017 21.5 0.3 0.0007 19.5 0.1 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain IclR PF01614.13 ETO13000.1 - 0.002 17.8 0.4 0.0029 17.2 0.3 1.3 1 0 0 1 1 1 1 Bacterial transcriptional regulator DUF241 PF03087.9 ETO13000.1 - 0.0057 16.1 2.3 0.0058 16.1 1.0 1.3 1 1 0 1 1 1 1 Arabidopsis protein of unknown function Translin PF01997.11 ETO13000.1 - 0.048 13.2 4.7 0.66 9.5 0.1 2.8 2 1 1 3 3 3 0 Translin family CRIC_ras_sig PF10534.4 ETO13000.1 - 0.087 12.8 0.1 0.44 10.6 0.1 2.1 1 1 0 1 1 1 0 Connector enhancer of kinase suppressor of ras DASH_Dad3 PF08656.5 ETO13000.1 - 0.14 11.8 0.4 0.7 9.6 0.0 2.1 2 1 0 2 2 2 0 DASH complex subunit Dad3 DUF3355 PF11835.3 ETO13000.1 - 0.14 11.9 0.4 0.36 10.5 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3355) IpaC_SipC PF09599.5 ETO13000.1 - 0.44 9.5 5.0 0.059 12.3 0.5 1.6 2 0 0 2 2 2 0 Salmonella-Shigella invasin protein C (IpaC_SipC) ING PF12998.2 ETO13000.1 - 3.2 8.0 7.2 1.6 9.0 0.5 2.1 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding FRG PF08867.6 ETO13000.1 - 3.7 8.1 8.5 14 6.2 2.8 2.8 1 1 1 2 2 2 0 FRG domain Capsid_NCLDV PF04451.7 ETO13001.1 - 0.099 11.6 2.1 2 7.3 0.6 2.1 1 1 1 2 2 2 0 Large eukaryotic DNA virus major capsid protein DEAD PF00270.24 ETO13004.1 - 3.1e-14 52.8 0.2 1.5e-13 50.5 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETO13004.1 - 5.3e-06 26.2 0.0 1.5e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain FANCI_S2 PF14676.1 ETO13005.1 - 0.03 14.2 0.2 0.28 11.0 0.0 2.2 2 0 0 2 2 2 0 FANCI solenoid 2 DUF4449 PF14613.1 ETO13006.1 - 0.00082 19.3 1.7 0.0016 18.4 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) RdRP_1 PF00680.15 ETO13006.1 - 0.053 11.7 0.0 0.081 11.1 0.0 1.2 1 0 0 1 1 1 0 RNA dependent RNA polymerase HATPase_c PF02518.21 ETO13007.1 - 2.4e-14 52.9 0.0 2.2e-13 49.8 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 ETO13007.1 - 4.6e-05 23.0 0.0 6.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BCDHK_Adom3 PF10436.4 ETO13008.1 - 2.7e-19 69.2 1.1 4e-19 68.7 0.8 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Pkinase PF00069.20 ETO13009.1 - 1.7e-55 187.9 0.8 3.8e-38 131.1 0.2 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO13009.1 - 4.7e-31 107.7 0.2 6.6e-24 84.3 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 ETO13009.1 - 0.00016 20.7 2.2 0.0035 16.3 0.0 3.0 2 2 1 3 3 3 1 Kinase-like Kdo PF06293.9 ETO13009.1 - 0.00054 19.0 0.0 0.0013 17.8 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO13009.1 - 0.04 13.6 0.1 0.04 13.6 0.0 1.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family MARCKS PF02063.12 ETO13009.1 - 0.064 13.1 7.6 0.091 12.5 5.3 1.2 1 0 0 1 1 1 0 MARCKS family MFS_2 PF13347.1 ETO13009.1 - 0.19 10.1 0.0 0.26 9.6 0.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein DUF2011 PF09428.5 ETO13009.1 - 3.2 7.6 10.4 0.34 10.7 3.1 2.2 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF2011) Pkinase_C PF00433.19 ETO13010.1 - 2.8 8.5 8.7 18 5.9 6.1 2.1 1 1 0 1 1 1 0 Protein kinase C terminal domain Spc7 PF08317.6 ETO13011.1 - 0.00085 18.0 11.4 0.0013 17.4 7.9 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Macoilin PF09726.4 ETO13011.1 - 0.2 9.8 13.2 0.49 8.6 9.1 1.5 1 1 0 1 1 1 0 Transmembrane protein Rootletin PF15035.1 ETO13011.1 - 2.6 7.9 16.3 0.18 11.7 6.7 2.0 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF106 PF01956.11 ETO13011.1 - 3.4 7.1 12.7 0.12 11.9 1.4 2.9 2 1 1 3 3 3 0 Integral membrane protein DUF106 Sec10 PF07393.6 ETO13012.1 - 5.5e-45 153.7 5.6 6.4e-45 153.5 3.9 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Eaf7 PF07904.8 ETO13012.1 - 0.046 13.7 1.3 0.73 9.8 0.3 2.7 2 0 0 2 2 2 0 Chromatin modification-related protein EAF7 Sec10 PF07393.6 ETO13013.1 - 1.1e-05 23.9 0.9 1.3e-05 23.6 0.6 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 ATP-gua_PtransN PF02807.10 ETO13015.1 - 2.3e-07 30.8 0.0 7.3e-07 29.2 0.0 1.9 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain DUF2052 PF09747.4 ETO13015.1 - 5.7 6.8 36.9 1 9.2 7.6 3.8 4 0 0 4 4 4 0 Coiled-coil domain containing protein (DUF2052) RNase_T PF00929.19 ETO13017.1 - 9.1e-16 58.5 0.1 9.1e-16 58.5 0.1 4.0 4 2 1 5 5 5 1 Exonuclease ESSS PF10183.4 ETO13017.1 - 0.1 12.9 1.2 0.25 11.7 0.1 2.3 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) WD40 PF00400.27 ETO13018.1 - 1.4e-13 50.0 6.5 1.5e-06 27.8 0.8 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat GEMIN8 PF15348.1 ETO13018.1 - 7.2 6.6 32.2 0.21 11.5 0.7 3.3 3 0 0 3 3 3 0 Gemini of Cajal bodies-associated protein 8 SIR2 PF02146.12 ETO13019.1 - 1.6e-09 37.7 1.3 8.8e-08 32.0 0.9 2.2 1 1 0 1 1 1 1 Sir2 family Mitochondr_Som1 PF11093.3 ETO13019.1 - 0.0019 17.9 0.2 0.016 15.0 0.0 2.3 2 0 0 2 2 2 1 Mitochondrial export protein Som1 zf-TRAF PF02176.13 ETO13019.1 - 0.088 13.1 4.4 0.092 13.1 1.5 2.1 2 0 0 2 2 2 0 TRAF-type zinc finger DUF572 PF04502.8 ETO13020.1 - 1.8e-65 221.3 18.8 2e-65 221.1 13.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF2730 PF10805.3 ETO13020.1 - 0.049 13.3 0.5 0.14 11.8 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Lar_restr_allev PF14354.1 ETO13020.1 - 0.21 11.9 2.4 6.1 7.2 0.1 2.8 1 1 1 2 2 2 0 Restriction alleviation protein Lar Pkinase PF00069.20 ETO13021.1 - 2.6e-51 174.2 0.0 3.1e-51 174.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO13021.1 - 4.3e-25 88.2 0.0 5.7e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 ETO13021.1 - 9.3e-06 26.0 1.3 1.5e-05 25.3 0.9 1.4 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 ETO13021.1 - 0.00088 18.3 0.0 0.001 18.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETO13021.1 - 0.089 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 ETO13021.1 - 0.11 11.5 0.1 0.23 10.5 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Secretin_N_2 PF07655.8 ETO13024.1 - 0.0047 17.2 13.6 0.0047 17.2 9.4 2.6 2 1 0 2 2 2 1 Secretin N-terminal domain UPF0139 PF03669.8 ETO13025.1 - 0.1 12.1 0.0 0.25 10.8 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) Arm PF00514.18 ETO13026.1 - 4.3e-10 39.0 0.2 0.093 12.5 0.0 5.1 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat CDC45 PF02724.9 ETO13026.1 - 0.2 9.6 3.4 0.27 9.2 2.4 1.1 1 0 0 1 1 1 0 CDC45-like protein GCIP PF13324.1 ETO13026.1 - 0.21 10.7 8.4 0.17 11.0 4.1 2.0 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting CENP-B_dimeris PF09026.5 ETO13026.1 - 0.84 9.9 14.1 2 8.7 9.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2457 PF10446.4 ETO13026.1 - 0.93 8.1 15.6 1.3 7.6 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 ETO13026.1 - 2.4 5.9 8.5 3.4 5.4 5.9 1.2 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 ETO13026.1 - 4.2 6.8 14.7 9 5.7 10.2 1.5 1 0 0 1 1 1 0 Nucleoplasmin CAP_GLY PF01302.20 ETO13027.1 - 0.067 12.9 0.2 0.11 12.2 0.1 1.4 1 1 0 1 1 1 0 CAP-Gly domain ShK PF01549.19 ETO13028.1 - 0.0024 18.1 4.8 0.0053 17.0 3.4 1.6 1 0 0 1 1 1 1 ShK domain-like Pkinase PF00069.20 ETO13029.1 - 3e-05 23.3 0.3 8.2e-05 21.8 0.0 1.8 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO13029.1 - 0.0032 16.5 0.0 0.0064 15.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 ETO13030.1 - 3.7e-36 124.5 0.0 2.6e-18 66.1 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO13030.1 - 9e-14 51.1 0.1 1.4e-08 34.1 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 ETO13030.1 - 0.013 14.3 0.4 0.021 13.6 0.2 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 ETO13030.1 - 0.037 13.1 0.1 0.065 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RGS PF00615.14 ETO13031.1 - 9.9e-05 22.4 0.9 0.00016 21.7 0.6 1.4 1 1 0 1 1 1 1 Regulator of G protein signaling domain FlxA PF14282.1 ETO13032.1 - 6.1 6.8 22.6 2 8.4 13.0 2.2 1 1 1 2 2 2 0 FlxA-like protein LUC7 PF03194.10 ETO13033.1 - 0.00034 20.2 1.6 0.00044 19.8 1.1 1.2 1 0 0 1 1 1 1 LUC7 N_terminus DUF1510 PF07423.6 ETO13033.1 - 0.00059 19.2 7.0 0.00072 18.9 4.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) CobT PF06213.7 ETO13033.1 - 0.02 14.0 5.4 0.023 13.8 3.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FLO_LFY PF01698.11 ETO13033.1 - 0.026 13.3 4.4 0.029 13.2 3.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Rtf2 PF04641.7 ETO13033.1 - 0.042 13.0 8.8 0.051 12.7 6.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger FSIP1 PF15554.1 ETO13033.1 - 0.18 10.5 12.2 0.21 10.3 8.4 1.1 1 0 0 1 1 1 0 FSIP1 family DUF4551 PF15087.1 ETO13033.1 - 0.62 8.3 7.8 0.77 8.0 5.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF3595 PF12166.3 ETO13033.1 - 1.8 7.2 10.5 2.1 7.0 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) DUF2457 PF10446.4 ETO13033.1 - 1.9 7.1 9.7 2.4 6.7 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Menin PF05053.8 ETO13033.1 - 2.3 6.2 10.6 2.8 6.0 7.4 1.2 1 0 0 1 1 1 0 Menin Zip PF02535.17 ETO13033.1 - 2.9 6.8 9.6 5.6 5.8 6.7 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter Nop25 PF09805.4 ETO13033.1 - 2.9 7.9 10.9 4.6 7.3 7.5 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) POX PF07526.6 ETO13033.1 - 3.2 7.9 8.2 5.9 7.1 5.7 1.5 1 0 0 1 1 1 0 Associated with HOX Paramyxo_ncap PF00973.14 ETO13033.1 - 3.7 6.1 6.0 4.3 5.9 4.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Pex14_N PF04695.8 ETO13033.1 - 4 7.4 11.3 7.5 6.6 7.8 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Tetraspannin PF00335.15 ETO13034.1 - 0.00066 19.0 2.5 0.0014 17.9 1.7 1.6 1 1 0 1 1 1 1 Tetraspanin family Claudin_2 PF13903.1 ETO13034.1 - 0.0018 18.0 0.8 0.17 11.5 0.0 2.1 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Menin PF05053.8 ETO13034.1 - 0.0053 14.9 2.3 0.0062 14.7 1.6 1.1 1 0 0 1 1 1 1 Menin Peptidase_S49_N PF08496.5 ETO13034.1 - 0.024 14.4 0.1 0.024 14.4 0.1 2.7 3 0 0 3 3 3 0 Peptidase family S49 N-terminal Sporozoite_P67 PF05642.6 ETO13034.1 - 0.033 12.0 2.7 0.04 11.7 1.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Neur_chan_memb PF02932.11 ETO13034.1 - 0.045 13.6 5.0 0.018 14.9 1.6 1.6 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Pex14_N PF04695.8 ETO13034.1 - 0.11 12.4 5.2 0.59 10.1 3.6 2.1 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM176 PF14851.1 ETO13034.1 - 0.22 11.2 1.7 0.37 10.4 1.2 1.5 1 0 0 1 1 1 0 FAM176 family Zip PF02535.17 ETO13034.1 - 1.2 8.0 10.8 1.5 7.7 7.1 1.7 1 1 0 1 1 1 0 ZIP Zinc transporter 2TM PF13239.1 ETO13034.1 - 1.3 9.1 6.4 0.38 10.8 0.9 2.2 2 0 0 2 2 2 0 2TM domain DUF2207 PF09972.4 ETO13034.1 - 1.3 7.5 10.4 0.14 10.6 0.8 2.1 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Apis_Csd PF11671.3 ETO13034.1 - 1.3 8.7 12.6 0.89 9.3 7.3 1.8 2 0 0 2 2 2 0 Complementary sex determiner protein DUF788 PF05620.6 ETO13034.1 - 1.9 8.2 7.7 1.4 8.7 1.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF788) Hid1 PF12722.2 ETO13034.1 - 2.1 5.9 17.8 2.5 5.6 11.7 1.3 1 1 0 2 2 2 0 High-temperature-induced dauer-formation protein Multi_Drug_Res PF00893.14 ETO13034.1 - 2.3 8.7 7.1 0.34 11.3 1.2 1.9 2 0 0 2 2 2 0 Small Multidrug Resistance protein DUF2101 PF09874.4 ETO13034.1 - 3.1 7.2 9.0 0.17 11.3 1.8 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) Vfa1 PF08432.5 ETO13034.1 - 5.4 7.0 12.8 0.25 11.3 3.2 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 TEX19 PF15553.1 ETO13035.1 - 0.48 10.2 4.5 0.58 10.0 0.1 2.0 1 1 1 2 2 2 0 Testis-expressed protein 19 Secretin_N_2 PF07655.8 ETO13035.1 - 8.4 6.8 24.0 2 8.8 13.0 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain Pkinase PF00069.20 ETO13036.1 - 2.2e-29 102.4 0.3 3.2e-29 101.8 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO13036.1 - 3.9e-14 52.3 0.6 8.5e-14 51.2 0.4 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO13036.1 - 0.0029 16.6 0.0 0.0043 16.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETO13036.1 - 0.0069 15.3 0.0 0.0087 15.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETO13036.1 - 0.011 15.5 0.1 0.24 11.0 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 ETO13036.1 - 0.022 13.5 0.4 0.037 12.8 0.0 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 ETO13036.1 - 0.036 13.4 0.1 0.069 12.4 0.0 1.4 1 1 0 1 1 1 0 RIO1 family WD40 PF00400.27 ETO13037.1 - 1.2e-35 120.1 12.5 6.2e-11 41.7 1.1 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO13037.1 - 4.1e-07 28.5 0.3 0.00052 18.2 0.1 2.7 2 1 1 3 3 3 2 Nucleoporin Nup120/160 CbiA PF01656.18 ETO13038.1 - 2.1e-39 134.9 0.1 3e-39 134.4 0.1 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 ETO13038.1 - 1.3e-12 47.4 0.0 4.4e-12 45.6 0.0 1.8 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 ETO13038.1 - 2.6e-11 43.1 0.6 9.1e-11 41.3 0.4 2.0 1 1 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.1 ETO13038.1 - 4.1e-11 43.0 0.1 8.2e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain YhjQ PF06564.7 ETO13038.1 - 1.9e-08 34.0 0.0 2.4e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 YhjQ protein Fer4_NifH PF00142.13 ETO13038.1 - 3.3e-08 33.0 0.1 1.1e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.6 ETO13038.1 - 2.1e-05 23.7 0.0 8.3e-05 21.7 0.0 2.0 2 0 0 2 2 2 1 VirC1 protein AAA_24 PF13479.1 ETO13038.1 - 0.014 15.0 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 ETO13038.1 - 0.015 14.1 0.1 0.026 13.3 0.0 1.3 1 0 0 1 1 1 0 ArgK protein DUF137 PF02006.11 ETO13038.1 - 0.02 14.3 0.1 0.15 11.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF137 ATP_bind_1 PF03029.12 ETO13038.1 - 0.021 14.3 0.1 0.074 12.5 0.0 1.9 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein SRP54 PF00448.17 ETO13038.1 - 0.051 13.0 0.1 0.14 11.5 0.1 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Methyltransf_24 PF13578.1 ETO13038.1 - 0.06 14.1 0.0 0.22 12.3 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain AAA_18 PF13238.1 ETO13038.1 - 0.068 13.4 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Peptidase_C14 PF00656.17 ETO13039.1 - 0.00016 21.4 0.4 0.00016 21.4 0.3 2.0 2 0 0 2 2 2 1 Caspase domain Merozoite_SPAM PF07133.6 ETO13039.1 - 0.0053 16.6 20.8 0.0053 16.6 14.4 2.2 2 0 0 2 2 2 1 Merozoite surface protein (SPAM) DDHD PF02862.12 ETO13039.1 - 0.095 12.4 1.8 0.16 11.7 1.3 1.3 1 0 0 1 1 1 0 DDHD domain DUF2011 PF09428.5 ETO13039.1 - 0.12 12.2 8.7 0.29 10.9 6.0 1.6 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2011) Vfa1 PF08432.5 ETO13039.1 - 0.65 9.9 14.5 1.4 8.8 10.1 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Sporozoite_P67 PF05642.6 ETO13039.1 - 1.5 6.5 6.1 2.4 5.9 4.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1762 PF08574.5 ETO13039.1 - 3.4 8.1 12.0 4.6 7.7 4.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1762) CAP_GLY PF01302.20 ETO13040.1 - 1.4e-05 24.7 0.1 2.7e-05 23.7 0.1 1.5 1 1 0 1 1 1 1 CAP-Gly domain Aa_trans PF01490.13 ETO13041.1 - 6.8e-50 169.7 31.8 2.6e-48 164.5 22.0 2.6 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein PH PF00169.24 ETO13043.1 - 0.0088 16.2 0.2 0.02 15.0 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 ETO13043.1 - 0.23 11.7 1.2 0.33 11.2 0.2 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain PhnJ PF06007.6 ETO13044.1 - 0.072 11.8 0.0 0.13 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ VWA_2 PF13519.1 ETO13047.1 - 2e-18 67.1 0.1 4.2e-18 66.0 0.1 1.5 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 ETO13047.1 - 4.1e-10 39.6 0.8 8.1e-10 38.6 0.1 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.1 ETO13047.1 - 4.8e-06 26.3 0.0 8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 ETO13047.1 - 0.00036 20.4 0.3 0.00085 19.2 0.1 1.7 2 0 0 2 2 2 1 vWA found in TerF C terminus Macoilin PF09726.4 ETO13048.1 - 7.4 4.7 9.1 9.4 4.3 6.3 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF3007 PF11460.3 ETO13049.1 - 0.093 12.8 0.1 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) COG2 PF06148.6 ETO13051.1 - 0.00044 20.1 3.1 0.0018 18.1 0.1 3.2 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 ETO13051.1 - 0.0018 18.1 2.8 0.046 13.5 0.0 3.3 3 0 0 3 3 3 1 Vps51/Vps67 AstE_AspA PF04952.9 ETO13051.1 - 0.02 13.8 0.0 0.037 12.8 0.0 1.4 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Med31 PF05669.7 ETO13051.1 - 0.26 11.0 3.2 0.61 9.8 0.2 3.0 2 1 1 3 3 3 0 SOH1 M16C_assoc PF08367.6 ETO13053.1 - 6.2e-12 44.9 0.1 7.9e-12 44.5 0.1 1.2 1 0 0 1 1 1 1 Peptidase M16C associated DUF4557 PF15101.1 ETO13054.1 - 0.00017 21.4 5.4 0.00018 21.4 3.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4557) BAF1_ABF1 PF04684.8 ETO13054.1 - 0.00093 18.1 13.0 0.0011 17.8 9.0 1.1 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor DSPc PF00782.15 ETO13054.1 - 0.0043 16.6 2.3 0.0049 16.4 0.0 2.1 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain DDHD PF02862.12 ETO13054.1 - 0.037 13.8 4.8 0.041 13.6 3.3 1.3 1 0 0 1 1 1 0 DDHD domain Herpes_env PF01673.13 ETO13054.1 - 0.058 11.9 7.5 0.072 11.6 5.2 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein DUF1682 PF07946.9 ETO13054.1 - 0.097 11.4 11.2 0.026 13.3 5.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) Band_3_cyto PF07565.8 ETO13054.1 - 0.16 11.4 5.8 0.19 11.2 4.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF940 PF06082.6 ETO13054.1 - 0.31 9.5 7.1 0.37 9.2 4.9 1.0 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) Bud13 PF09736.4 ETO13054.1 - 0.38 10.9 14.8 0.56 10.4 10.3 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex RP-C_C PF11800.3 ETO13054.1 - 0.44 10.2 6.6 0.54 9.9 4.6 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Mem_trans PF03547.13 ETO13054.1 - 0.6 8.3 3.3 0.68 8.1 2.3 1.1 1 0 0 1 1 1 0 Membrane transport protein Ndc1_Nup PF09531.5 ETO13054.1 - 0.66 8.3 7.5 0.81 8.0 5.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Spore_coat_CotO PF14153.1 ETO13054.1 - 0.67 9.3 17.6 0.9 8.9 12.2 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF4175 PF13779.1 ETO13054.1 - 0.89 7.1 21.2 1 6.9 14.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Presenilin PF01080.12 ETO13054.1 - 0.91 8.2 5.5 1.1 7.9 3.8 1.2 1 0 0 1 1 1 0 Presenilin OATP PF03137.15 ETO13054.1 - 1.2 7.0 6.6 2.1 6.3 4.6 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family UPF0560 PF10577.4 ETO13054.1 - 2 6.5 12.1 2.5 6.2 8.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Neur_chan_memb PF02932.11 ETO13054.1 - 2.5 7.9 8.7 3.3 7.5 6.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Gti1_Pac2 PF09729.4 ETO13054.1 - 3.1 7.6 8.2 4.7 7.0 5.7 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family Gag_spuma PF03276.9 ETO13054.1 - 3.3 5.9 15.6 4 5.6 10.8 1.1 1 0 0 1 1 1 0 Spumavirus gag protein HGTP_anticodon2 PF12745.2 ETO13054.1 - 4.7 6.2 15.7 7.4 5.6 10.9 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs FAM60A PF15396.1 ETO13054.1 - 5.1 6.7 11.9 6.7 6.3 8.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF3464 PF11947.3 ETO13054.1 - 7.9 5.9 7.9 12 5.3 5.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) ALAD PF00490.16 ETO13055.1 - 9e-50 169.3 0.0 1e-49 169.1 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase ALAD PF00490.16 ETO13056.1 - 2e-43 148.5 0.1 1.2e-39 136.0 0.0 2.4 1 1 1 2 2 2 2 Delta-aminolevulinic acid dehydratase AAA_22 PF13401.1 ETO13057.1 - 0.00049 20.2 0.5 0.0074 16.4 0.3 2.3 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 ETO13057.1 - 0.0054 16.4 0.1 0.13 11.9 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 ETO13057.1 - 0.0086 16.0 0.4 0.026 14.5 0.3 1.8 1 1 0 1 1 1 1 AAA ATPase domain Mvb12 PF09452.5 ETO13057.1 - 2.5 8.3 7.2 3.9 7.7 3.7 2.3 2 1 0 2 2 2 0 ESCRT-I subunit Mvb12 Innate_immun PF12782.2 ETO13058.1 - 0.05 12.8 13.9 0.085 12.0 9.6 1.4 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family BcrAD_BadFG PF01869.15 ETO13059.1 - 0.047 12.9 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family C2 PF00168.25 ETO13060.1 - 2.4e-08 33.7 0.0 4.5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 C2 domain EF-hand_6 PF13405.1 ETO13062.1 - 0.0001 21.8 5.0 0.0061 16.3 0.3 3.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 ETO13062.1 - 0.0016 17.6 0.6 0.0016 17.6 0.4 3.5 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.1 ETO13062.1 - 0.011 15.3 0.3 0.011 15.3 0.2 3.3 2 2 1 3 3 3 0 EF-hand domain pair EF-hand_7 PF13499.1 ETO13062.1 - 0.032 14.3 0.4 0.032 14.3 0.3 2.4 1 1 1 2 2 2 0 EF-hand domain pair DUF2431 PF10354.4 ETO13063.1 - 2.2e-25 89.5 5.3 1.7e-18 67.1 0.0 3.6 2 1 2 4 4 4 3 Domain of unknown function (DUF2431) Methyltransf_26 PF13659.1 ETO13063.1 - 0.06 13.3 0.0 0.11 12.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain DUF607 PF04678.8 ETO13064.1 - 0.028 14.3 1.6 3.5 7.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF607 CarD_CdnL_TRCF PF02559.11 ETO13066.1 - 0.17 11.9 3.1 0.32 11.0 2.1 1.5 1 1 0 1 1 1 0 CarD-like/TRCF domain PDGF_N PF04692.8 ETO13066.1 - 0.38 11.2 0.1 0.38 11.2 0.1 2.2 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region adh_short PF00106.20 ETO13067.1 - 0.00068 19.5 0.0 0.00094 19.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Glyco_hydro_31 PF01055.21 ETO13068.1 - 2.2e-11 43.2 0.4 2.4e-11 43.1 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Fibrinogen_BP PF08017.6 ETO13069.1 - 0.0054 14.9 1.0 0.0064 14.7 0.7 1.1 1 0 0 1 1 1 1 Fibrinogen binding protein Rho_GDI PF02115.12 ETO13069.1 - 0.016 14.5 1.6 0.05 13.0 0.0 2.0 2 0 0 2 2 2 0 RHO protein GDP dissociation inhibitor Secretin_N_2 PF07655.8 ETO13069.1 - 0.25 11.7 5.3 0.1 12.9 1.8 1.7 2 0 0 2 2 2 0 Secretin N-terminal domain Pkinase PF00069.20 ETO13070.1 - 0.00012 21.2 0.0 0.0002 20.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Spore_YabQ PF09578.5 ETO13071.1 - 0.85 9.6 6.6 0.62 10.0 0.7 2.4 2 0 0 2 2 2 0 Spore cortex protein YabQ (Spore_YabQ) Ion_trans PF00520.26 ETO13072.1 - 8.9e-56 188.3 32.0 4.6e-34 117.4 3.0 2.6 3 0 0 3 3 3 2 Ion transport protein Ion_trans PF00520.26 ETO13073.1 - 2.5e-64 216.2 53.1 5.8e-32 110.5 15.6 4.5 5 0 0 5 5 5 4 Ion transport protein PKD_channel PF08016.7 ETO13073.1 - 6.7e-07 28.0 31.8 3.1e-06 25.9 7.0 5.2 4 1 0 5 5 5 4 Polycystin cation channel Mito_fiss_reg PF05308.6 ETO13074.1 - 0.00032 20.1 11.1 0.00032 20.1 7.7 2.4 2 0 0 2 2 2 1 Mitochondrial fission regulator TPR_MLP1_2 PF07926.7 ETO13074.1 - 0.0066 16.2 46.3 0.03 14.0 16.6 3.6 3 0 0 3 3 3 2 TPR/MLP1/MLP2-like protein IncA PF04156.9 ETO13074.1 - 0.11 12.0 0.0 0.11 12.0 0.0 4.2 3 1 1 4 4 4 0 IncA protein DUF2353 PF09789.4 ETO13074.1 - 1 8.5 35.9 2.5 7.2 18.3 3.4 2 1 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Tubulin_C PF03953.12 ETO13075.1 - 3.7e-50 169.1 0.1 5.7e-50 168.5 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Laminin_G_3 PF13385.1 ETO13076.1 - 0.00054 20.2 0.0 0.0013 19.0 0.0 1.7 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Pentaxin PF00354.12 ETO13076.1 - 0.018 14.4 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Pentaxin family Syja_N PF02383.13 ETO13077.1 - 6.4e-47 159.8 5.6 1.4e-26 92.9 0.0 3.6 2 1 1 3 3 3 2 SacI homology domain CDC45 PF02724.9 ETO13077.1 - 0.0069 14.4 10.5 0.0099 13.9 7.3 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF1510 PF07423.6 ETO13077.1 - 0.053 12.8 24.1 0.079 12.3 15.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF663 PF04950.7 ETO13077.1 - 0.1 11.5 5.8 0.15 10.9 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF663) DUF4637 PF15470.1 ETO13077.1 - 0.1 12.2 7.5 0.23 11.0 5.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF2457 PF10446.4 ETO13077.1 - 0.12 11.0 27.5 0.22 10.2 19.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CobT PF06213.7 ETO13077.1 - 0.21 10.6 16.0 0.37 9.8 11.1 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Strabismus PF06638.6 ETO13077.1 - 0.47 8.6 3.2 0.78 7.9 2.2 1.3 1 0 0 1 1 1 0 Strabismus protein Nop14 PF04147.7 ETO13077.1 - 0.63 7.8 24.1 0.063 11.1 13.8 1.3 2 0 0 2 2 2 0 Nop14-like family NARP1 PF12569.3 ETO13077.1 - 0.82 8.3 11.0 1.4 7.5 7.6 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Pox_Ag35 PF03286.9 ETO13077.1 - 0.9 9.0 20.1 1.8 8.0 13.9 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CMV_1a PF12467.3 ETO13077.1 - 0.98 9.7 14.0 0.37 11.1 7.0 2.0 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family TRAP_alpha PF03896.11 ETO13077.1 - 7.3 5.4 12.0 14 4.5 8.3 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Cellulose_synt PF03552.9 ETO13077.1 - 8.7 4.5 7.1 13 3.9 4.9 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF1754 PF08555.5 ETO13077.1 - 9.6 6.8 29.8 4.8 7.8 18.4 1.9 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Tom22 PF04281.8 ETO13078.1 - 0.02 14.4 0.9 0.032 13.7 0.6 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Radial_spoke_3 PF06098.6 ETO13078.1 - 0.021 13.8 3.0 0.025 13.6 2.1 1.1 1 0 0 1 1 1 0 Radial spoke protein 3 GOLD_2 PF13897.1 ETO13078.1 - 0.15 12.2 1.4 0.23 11.7 0.9 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Helitron_like_N PF14214.1 ETO13078.1 - 0.15 11.7 0.7 1.3 8.7 0.0 2.2 1 1 0 2 2 2 0 Helitron helicase-like domain at N-terminus Peptidase_S64 PF08192.6 ETO13078.1 - 0.69 8.1 4.7 0.77 8.0 3.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 UCH PF00443.24 ETO13079.1 - 1.1e-10 41.1 0.1 1.1e-10 41.1 0.1 3.3 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO13079.1 - 0.0005 19.6 0.3 0.0005 19.6 0.2 4.0 3 1 1 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase EF-hand_6 PF13405.1 ETO13079.1 - 0.0035 17.0 0.0 0.013 15.3 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.27 ETO13079.1 - 0.0038 16.4 0.0 0.012 14.8 0.0 2.0 1 0 0 1 1 1 1 EF hand Ctr PF04145.10 ETO13079.1 - 0.029 14.4 2.2 0.11 12.5 0.1 2.9 2 1 1 3 3 3 0 Ctr copper transporter family BUD22 PF09073.5 ETO13079.1 - 5 6.0 31.6 0.67 8.9 17.7 2.1 2 0 0 2 2 2 0 BUD22 Peptidase_U4 PF03419.8 ETO13080.1 - 0.13 11.2 10.1 0.25 10.3 7.0 1.5 1 0 0 1 1 1 0 Sporulation factor SpoIIGA HCaRG PF07258.9 ETO13081.1 - 7.6e-16 58.1 0.7 8.4e-16 58.0 0.5 1.1 1 0 0 1 1 1 1 HCaRG protein Nuc_sug_transp PF04142.10 ETO13082.1 - 1.1e-40 139.2 12.6 1.4e-40 138.9 8.8 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 ETO13082.1 - 4e-08 33.3 25.2 9.3e-07 28.9 0.3 2.8 2 1 1 3 3 3 2 EamA-like transporter family TPT PF03151.11 ETO13082.1 - 0.0008 19.0 14.6 0.035 13.7 8.1 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 ETO13082.1 - 0.0046 17.1 0.2 0.0046 17.1 0.1 2.8 2 1 1 3 3 3 1 Multidrug resistance efflux transporter UAA PF08449.6 ETO13082.1 - 0.014 14.3 4.2 0.012 14.5 2.2 1.5 1 1 0 1 1 1 0 UAA transporter family SPRY PF00622.23 ETO13083.1 - 0.017 15.1 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 SPRY domain AAA_11 PF13086.1 ETO13084.1 - 6.1e-53 179.8 0.3 9.4e-53 179.2 0.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETO13084.1 - 2.2e-15 56.1 1.2 5.1e-15 54.9 0.8 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 ETO13084.1 - 6.6e-15 55.2 0.1 4.4e-10 39.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.1 ETO13084.1 - 2.9e-12 46.4 0.9 5.1e-12 45.6 0.3 1.7 2 0 0 2 2 1 1 AAA domain DUF2075 PF09848.4 ETO13084.1 - 1.1e-06 27.9 1.2 1.1e-05 24.6 0.8 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 ETO13084.1 - 1.3e-06 28.3 0.0 2.1e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 ETO13084.1 - 3.9e-06 26.3 0.1 0.0016 17.7 0.0 2.3 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 ETO13084.1 - 2.7e-05 23.8 0.1 7.7e-05 22.3 0.1 2.0 1 1 0 1 1 1 1 Helicase PIF1 PF05970.9 ETO13084.1 - 7.5e-05 21.8 0.1 0.24 10.3 0.0 2.3 2 0 0 2 2 2 2 PIF1-like helicase SNF2_N PF00176.18 ETO13084.1 - 9.9e-05 21.2 0.1 0.00018 20.4 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 ETO13084.1 - 0.00013 21.4 0.4 0.00044 19.7 0.1 1.9 1 1 0 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.11 ETO13084.1 - 0.00021 20.6 0.1 0.00051 19.3 0.0 1.6 2 0 0 2 2 2 1 PhoH-like protein Viral_helicase1 PF01443.13 ETO13084.1 - 0.0011 18.5 0.1 0.0056 16.2 0.0 2.0 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA PF00004.24 ETO13084.1 - 0.0019 18.3 0.0 0.0054 16.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 ETO13084.1 - 0.0027 17.1 0.3 0.01 15.2 0.1 2.1 2 1 0 2 2 2 1 IstB-like ATP binding protein KaiC PF06745.8 ETO13084.1 - 0.005 15.9 0.0 0.0089 15.1 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.1 ETO13084.1 - 0.0062 16.6 0.1 0.018 15.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 ETO13084.1 - 0.01 16.1 0.3 0.086 13.1 0.2 2.2 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETO13084.1 - 0.011 15.7 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 ETO13084.1 - 0.012 15.0 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 ETO13084.1 - 0.013 15.2 0.0 0.03 14.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SE PF00437.15 ETO13084.1 - 0.013 14.3 0.0 0.029 13.2 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_10 PF12846.2 ETO13084.1 - 0.022 14.2 0.0 0.043 13.2 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain SRP54 PF00448.17 ETO13084.1 - 0.024 14.0 0.3 0.079 12.4 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NACHT PF05729.7 ETO13084.1 - 0.04 13.5 0.0 0.1 12.2 0.0 1.7 2 0 0 2 2 1 0 NACHT domain Sigma54_activat PF00158.21 ETO13084.1 - 0.058 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 ETO13084.1 - 0.069 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Flavi_DEAD PF07652.9 ETO13084.1 - 0.093 12.4 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain VPS9 PF02204.13 ETO13085.1 - 2.9e-09 36.8 3.3 3.6e-07 30.1 2.3 2.6 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Orthoreo_P10 PF07204.6 ETO13085.1 - 0.064 13.0 0.3 0.15 11.8 0.2 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 FYVE PF01363.16 ETO13086.1 - 3.4e-12 46.0 16.4 3.4e-12 46.0 11.4 3.2 2 1 0 2 2 2 1 FYVE zinc finger FANCI_S3 PF14677.1 ETO13086.1 - 0.039 13.3 0.1 0.24 10.7 0.0 2.0 2 0 0 2 2 2 0 FANCI solenoid 3 adh_short PF00106.20 ETO13087.1 - 3.1e-09 36.9 0.1 5.6e-09 36.1 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETO13087.1 - 1.1e-05 25.3 0.1 1.3e-05 25.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 ETO13087.1 - 0.0019 17.9 0.2 0.0033 17.1 0.1 1.5 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.5 ETO13087.1 - 0.0022 17.7 0.1 0.003 17.2 0.1 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_2 PF03446.10 ETO13087.1 - 0.0031 17.3 0.0 0.0076 16.0 0.0 1.6 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 ETO13087.1 - 0.0052 16.2 0.1 0.0095 15.3 0.0 1.5 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 ETO13087.1 - 0.022 14.6 0.2 0.029 14.2 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RNA_pol_Rpb1_5 PF04998.12 ETO13087.1 - 0.077 12.2 1.6 0.093 11.9 1.1 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 AAA_12 PF13087.1 ETO13088.1 - 2.3e-59 200.1 0.2 2.8e-59 199.8 0.2 1.1 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 ETO13088.1 - 0.00051 19.6 0.0 0.00068 19.2 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 ETO13088.1 - 0.00052 20.1 0.1 0.00097 19.2 0.0 1.5 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain RGS PF00615.14 ETO13089.1 - 0.012 15.6 1.2 0.018 15.1 0.0 1.8 2 0 0 2 2 2 0 Regulator of G protein signaling domain SOBP PF15279.1 ETO13090.1 - 2.6e-07 31.3 26.4 2.6e-07 31.3 18.3 1.9 2 0 0 2 2 2 1 Sine oculis-binding protein MIP-T3 PF10243.4 ETO13090.1 - 4 5.8 32.1 0.16 10.4 18.1 1.6 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Glyco_transf_25 PF01755.12 ETO13091.1 - 0.017 14.7 0.2 0.039 13.6 0.1 1.6 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Homeobox_KN PF05920.6 ETO13091.1 - 0.064 12.9 0.0 0.23 11.1 0.0 1.9 1 0 0 1 1 1 0 Homeobox KN domain Pkinase PF00069.20 ETO13092.1 - 3.5e-14 52.5 0.0 4.2e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_C PF00433.19 ETO13092.1 - 5.5e-06 26.8 0.6 1.1e-05 25.8 0.4 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Pkinase_Tyr PF07714.12 ETO13092.1 - 1.6e-05 24.0 0.0 2.2e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 ETO13094.1 - 0.0026 16.9 0.1 0.0054 15.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Sec16_C PF12931.2 ETO13094.1 - 0.022 14.4 0.2 0.041 13.6 0.2 1.4 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 Mucin PF01456.12 ETO13094.1 - 3.1 7.5 13.7 0.36 10.6 3.1 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF2457 PF10446.4 ETO13096.1 - 0.00018 20.3 15.1 0.00027 19.8 10.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Nop14 PF04147.7 ETO13096.1 - 0.00034 18.6 17.2 0.00046 18.2 11.9 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.7 ETO13096.1 - 0.0011 18.3 15.6 0.0016 17.7 10.8 1.2 1 0 0 1 1 1 1 SDA1 Daxx PF03344.10 ETO13096.1 - 0.0058 15.1 22.0 0.011 14.3 15.2 1.3 1 0 0 1 1 1 1 Daxx Family TFIIA PF03153.8 ETO13096.1 - 0.022 14.6 10.2 0.035 13.9 7.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Astro_capsid PF03115.9 ETO13096.1 - 0.039 12.2 3.6 0.054 11.7 2.5 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF2722 PF10846.3 ETO13096.1 - 0.051 12.6 5.7 0.078 11.9 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF31 PF01732.11 ETO13096.1 - 0.052 12.8 0.4 0.083 12.1 0.3 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) Gti1_Pac2 PF09729.4 ETO13096.1 - 0.18 11.6 3.6 0.42 10.4 2.5 1.6 1 0 0 1 1 1 0 Gti1/Pac2 family Ycf1 PF05758.7 ETO13096.1 - 0.24 9.0 9.4 0.31 8.7 6.3 1.4 1 1 0 1 1 1 0 Ycf1 Sporozoite_P67 PF05642.6 ETO13096.1 - 0.26 9.0 6.6 0.38 8.5 4.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RXT2_N PF08595.6 ETO13096.1 - 0.41 10.4 13.6 1.1 9.0 9.4 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2151 PF10221.4 ETO13096.1 - 0.9 7.6 9.9 0.5 8.4 5.5 1.5 2 0 0 2 2 2 0 Cell cycle and development regulator RNA_pol_Rpc4 PF05132.9 ETO13096.1 - 2.5 8.0 6.6 5.7 6.9 4.6 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 YqfQ PF14181.1 ETO13096.1 - 2.6 8.0 11.5 7.9 6.5 7.9 1.8 1 0 0 1 1 1 0 YqfQ-like protein Sigma70_ner PF04546.8 ETO13096.1 - 4.7 6.7 19.5 13 5.2 13.5 1.8 1 0 0 1 1 1 0 Sigma-70, non-essential region Mpp10 PF04006.7 ETO13096.1 - 5.2 5.3 28.1 7.6 4.7 19.5 1.2 1 0 0 1 1 1 0 Mpp10 protein Paf1 PF03985.8 ETO13096.1 - 5.6 5.5 23.6 12 4.4 16.3 1.5 1 0 0 1 1 1 0 Paf1 VID27 PF08553.5 ETO13096.1 - 7.9 4.5 22.6 12 3.9 15.6 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein HSP90 PF00183.13 ETO13096.1 - 8 4.7 21.4 12 4.1 14.8 1.2 1 0 0 1 1 1 0 Hsp90 protein HEAT PF02985.17 ETO13098.1 - 1.5e-09 37.1 0.5 3.8 7.8 0.0 5.5 5 0 0 5 5 5 3 HEAT repeat Proteasom_PSMB PF10508.4 ETO13098.1 - 1.3e-06 27.0 2.8 0.0034 15.7 0.0 2.0 1 1 1 2 2 2 2 Proteasome non-ATPase 26S subunit HEAT_2 PF13646.1 ETO13098.1 - 7.7e-06 26.1 0.0 0.024 14.9 0.0 2.4 2 1 0 2 2 2 2 HEAT repeats CLASP_N PF12348.3 ETO13098.1 - 0.00013 21.4 1.0 0.0027 17.1 0.3 2.7 1 1 1 2 2 2 1 CLASP N terminal Adaptin_N PF01602.15 ETO13098.1 - 0.00024 19.6 2.4 0.00038 18.9 0.3 1.9 2 0 0 2 2 2 1 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 ETO13098.1 - 0.0083 16.4 0.2 0.11 12.9 0.0 2.4 2 1 1 3 3 3 1 Vacuolar 14 Fab1-binding region TAN PF11640.3 ETO13098.1 - 0.018 14.7 0.5 0.13 11.9 0.0 2.3 2 1 0 2 2 2 0 Telomere-length maintenance and DNA damage repair DUF2435 PF10363.4 ETO13098.1 - 0.045 13.6 0.9 0.24 11.3 0.0 2.4 2 2 1 3 3 3 0 Protein of unknown function (DUF2435) Cnd1 PF12717.2 ETO13098.1 - 0.096 12.5 3.3 0.25 11.1 0.6 2.2 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 RICTOR_V PF14668.1 ETO13099.1 - 0.0015 18.4 3.6 0.43 10.5 0.2 3.1 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR, domain 5 Arm PF00514.18 ETO13099.1 - 0.24 11.2 4.5 19 5.2 0.1 4.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Exo_endo_phos PF03372.18 ETO13100.1 - 8.7e-09 35.6 0.0 1.4e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Myb_DNA-binding PF00249.26 ETO13101.1 - 0.006 16.6 0.5 0.051 13.6 0.0 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain PseudoU_synth_2 PF00849.17 ETO13102.1 - 6.5e-19 68.3 10.0 1.6e-17 63.8 6.0 2.7 2 1 0 2 2 2 1 RNA pseudouridylate synthase MIP-T3 PF10243.4 ETO13102.1 - 0.00046 18.7 15.4 0.00046 18.7 10.7 2.0 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 Daxx PF03344.10 ETO13102.1 - 0.094 11.1 33.2 0.17 10.3 23.0 1.4 1 0 0 1 1 1 0 Daxx Family Hid1 PF12722.2 ETO13102.1 - 5.6 4.5 22.8 8.2 3.9 15.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GAGA_bind PF06217.7 ETO13103.1 - 0.029 14.3 10.3 0.032 14.1 7.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family SID-1_RNA_chan PF13965.1 ETO13103.1 - 0.89 7.6 3.4 1 7.4 2.4 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Sec62 PF03839.11 ETO13103.1 - 2.4 7.5 17.8 3.3 7.0 12.3 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 GEMIN8 PF15348.1 ETO13103.1 - 5.2 7.0 18.7 9.9 6.1 12.9 1.5 1 1 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DAGK_acc PF00609.14 ETO13104.1 - 0.08 13.0 0.3 0.1 12.7 0.2 1.1 1 0 0 1 1 1 0 Diacylglycerol kinase accessory domain tRNA-synt_1b PF00579.20 ETO13105.1 - 8.4e-34 117.0 0.0 3.5e-33 114.9 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) HEAT_2 PF13646.1 ETO13107.1 - 0.11 12.7 0.0 21 5.4 0.0 2.6 2 0 0 2 2 2 0 HEAT repeats Secretin_N_2 PF07655.8 ETO13107.1 - 5.8 7.3 13.7 11 6.5 9.5 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain Aminotran_1_2 PF00155.16 ETO13109.1 - 3.3e-06 26.2 0.0 4.3e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF2762 PF10960.3 ETO13109.1 - 0.048 13.3 1.3 0.075 12.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2762) DUF2681 PF10883.3 ETO13109.1 - 0.2 11.8 0.5 1.7 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) HEAT PF02985.17 ETO13111.1 - 1.3e-29 99.5 8.6 0.0012 18.6 0.0 9.0 9 0 0 9 9 9 7 HEAT repeat HEAT_2 PF13646.1 ETO13111.1 - 4.9e-21 74.8 5.9 3.5e-07 30.3 0.1 5.3 3 1 3 6 6 6 4 HEAT repeats Vac14_Fab1_bd PF12755.2 ETO13111.1 - 1.4e-07 31.7 1.3 0.0073 16.6 0.0 4.5 3 1 3 6 6 5 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 ETO13111.1 - 3.6e-06 27.2 9.0 0.0034 17.8 0.0 6.3 7 0 0 7 7 7 1 HEAT-like repeat Adaptin_N PF01602.15 ETO13111.1 - 9.2e-06 24.2 5.0 0.00017 20.0 1.8 3.7 2 1 0 2 2 2 1 Adaptin N terminal region CLASP_N PF12348.3 ETO13111.1 - 0.00019 20.8 0.6 0.33 10.2 0.0 4.3 3 1 1 4 4 4 1 CLASP N terminal Cnd1 PF12717.2 ETO13111.1 - 0.0012 18.7 0.7 1.4 8.7 0.0 4.4 2 2 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 DUF3554 PF12074.3 ETO13111.1 - 0.0034 16.8 0.1 0.73 9.2 0.0 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF3554) DUF3699 PF12480.3 ETO13111.1 - 0.0059 16.2 0.1 0.025 14.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3699) Cohesin_HEAT PF12765.2 ETO13111.1 - 0.03 14.2 6.7 0.68 9.9 0.0 5.6 8 0 0 8 8 7 0 HEAT repeat associated with sister chromatid cohesion Arm PF00514.18 ETO13111.1 - 0.12 12.2 0.4 8.7 6.3 0.0 3.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat YpjP PF14005.1 ETO13111.1 - 0.12 12.1 0.1 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 YpjP-like protein Proteasom_PSMB PF10508.4 ETO13111.1 - 0.21 9.8 2.8 3.4 5.8 0.1 2.7 1 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit Ran_BP1 PF00638.13 ETO13112.1 - 2.9e-12 46.6 2.0 2.9e-12 46.6 1.4 1.9 2 0 0 2 2 2 1 RanBP1 domain DUF2663 PF10864.3 ETO13113.1 - 0.19 11.9 1.5 0.35 11.0 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) Tmemb_9 PF05434.6 ETO13113.1 - 5.7 6.6 9.6 5.4 6.7 0.3 2.3 1 1 1 2 2 2 0 TMEM9 MVP_shoulder PF11978.3 ETO13114.1 - 0.044 13.6 0.8 1 9.2 0.1 2.5 2 0 0 2 2 2 0 Shoulder domain Clathrin_lg_ch PF01086.12 ETO13115.1 - 4.9e-08 33.1 2.6 6.9e-08 32.6 1.8 1.3 1 1 0 1 1 1 1 Clathrin light chain Med22 PF06179.7 ETO13115.1 - 0.0014 18.5 1.2 0.0022 17.9 0.9 1.5 1 1 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex SPRY PF00622.23 ETO13117.1 - 5.7e-13 49.0 0.6 1e-12 48.1 0.4 1.4 1 0 0 1 1 1 1 SPRY domain MMR_HSR1 PF01926.18 ETO13118.1 - 5.4e-15 55.3 0.0 1.8e-14 53.6 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETO13118.1 - 2.2e-07 30.2 0.1 4.8e-07 29.1 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B IIGP PF05049.8 ETO13118.1 - 3.2e-05 22.9 0.0 5.1e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AIG1 PF04548.11 ETO13118.1 - 0.00048 19.2 0.3 0.0029 16.7 0.0 2.2 2 0 0 2 2 2 1 AIG1 family DUF258 PF03193.11 ETO13118.1 - 0.00061 19.0 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MobB PF03205.9 ETO13118.1 - 0.012 15.3 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Sporozoite_P67 PF05642.6 ETO13118.1 - 0.013 13.4 0.0 0.016 13.1 0.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Dynamin_N PF00350.18 ETO13118.1 - 0.083 12.7 0.8 1.1 9.0 0.0 2.9 3 1 1 4 4 4 0 Dynamin family Nucleoplasmin PF03066.10 ETO13118.1 - 0.085 12.3 0.7 0.14 11.7 0.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF4611 PF15387.1 ETO13118.1 - 0.12 12.5 1.9 0.23 11.6 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) PHD_2 PF13831.1 ETO13120.1 - 2.3e-11 42.8 4.8 7.8e-11 41.1 3.3 2.0 1 0 0 1 1 1 1 PHD-finger PHD PF00628.24 ETO13120.1 - 1.2e-08 34.4 7.7 4.5e-08 32.6 5.3 2.1 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H_2 PF13832.1 ETO13120.1 - 1e-07 31.9 0.9 1e-07 31.9 0.6 3.2 2 1 1 3 3 3 1 PHD-zinc-finger like domain Prok-RING_1 PF14446.1 ETO13120.1 - 0.006 16.2 3.4 0.006 16.2 2.3 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 Pkinase PF00069.20 ETO13121.1 - 1.4e-26 93.2 0.5 2.4e-26 92.4 0.4 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO13121.1 - 9.2e-15 54.4 0.3 1.9e-14 53.3 0.2 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pyrophosphatase PF00719.14 ETO13123.1 - 4.1e-42 143.2 0.1 1.8e-41 141.1 0.0 1.9 1 1 0 1 1 1 1 Inorganic pyrophosphatase Hepatitis_core PF00906.15 ETO13123.1 - 0.064 12.9 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Hepatitis core antigen CTD PF12815.2 ETO13125.1 - 0.038 14.4 0.1 0.038 14.4 0.1 1.9 2 0 0 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 RasGEF PF00617.14 ETO13127.1 - 1.7e-13 50.7 0.1 2e-13 50.5 0.1 1.0 1 0 0 1 1 1 1 RasGEF domain Sulf_coat_C PF12193.3 ETO13127.1 - 0.15 11.8 0.1 0.64 9.8 0.0 1.9 1 1 1 2 2 2 0 Sulfolobus virus coat protein C terminal WD40 PF00400.27 ETO13128.1 - 1.2e-71 234.2 17.2 8.1e-12 44.5 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO13128.1 - 1.8e-08 33.0 4.9 0.21 9.6 0.1 5.1 1 1 3 4 4 4 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO13128.1 - 2.7e-08 33.5 0.2 0.00039 19.9 0.0 3.0 1 1 0 1 1 1 1 PQQ-like domain DUF1258 PF06869.7 ETO13128.1 - 0.00011 21.4 1.0 0.33 10.0 0.0 3.9 1 1 3 4 4 4 2 Protein of unknown function (DUF1258) Cytochrom_D1 PF02239.11 ETO13128.1 - 0.00016 20.0 3.0 0.0067 14.7 0.1 2.7 2 1 1 3 3 3 2 Cytochrome D1 heme domain Me-amine-dh_H PF06433.6 ETO13128.1 - 0.0026 16.4 0.0 0.065 11.8 0.0 2.7 1 1 2 3 3 3 2 Methylamine dehydrogenase heavy chain (MADH) DUF1513 PF07433.6 ETO13128.1 - 0.0085 15.0 0.1 0.14 11.0 0.0 2.6 1 1 2 3 3 3 1 Protein of unknown function (DUF1513) BBS2_Mid PF14783.1 ETO13128.1 - 0.012 15.4 3.4 10 5.9 0.1 4.5 2 2 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Mid2 PF04478.7 ETO13128.1 - 0.11 11.8 5.0 14 5.1 0.0 4.2 2 1 2 5 5 5 0 Mid2 like cell wall stress sensor PAN_3 PF08277.7 ETO13128.1 - 0.15 11.6 4.4 4.6 6.9 0.0 4.0 2 1 2 4 4 4 0 PAN-like domain PD40 PF07676.7 ETO13128.1 - 1.7 8.4 4.9 40 4.0 0.0 4.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat ABC2_membrane_4 PF12730.2 ETO13129.1 - 0.012 14.8 0.8 0.012 14.8 0.6 2.1 1 1 1 2 2 2 0 ABC-2 family transporter protein DUF4064 PF13273.1 ETO13129.1 - 0.016 15.2 0.3 0.016 15.2 0.2 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF1469 PF07332.6 ETO13129.1 - 0.7 9.6 8.2 5.3 6.7 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Claudin_2 PF13903.1 ETO13129.1 - 6.1 6.5 16.9 0.84 9.2 5.8 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction zf-RING_2 PF13639.1 ETO13130.1 - 1.4e-12 47.1 10.2 3.4e-12 45.9 7.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 ETO13130.1 - 5.1e-06 26.0 5.9 8.8e-06 25.3 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO13130.1 - 1.8e-05 24.6 9.3 3.5e-05 23.7 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO13130.1 - 3.4e-05 23.4 8.8 3.6e-05 23.3 5.0 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 ETO13130.1 - 0.00017 21.6 9.7 0.00047 20.2 6.7 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 ETO13130.1 - 0.0048 16.5 9.0 0.013 15.1 6.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 ETO13130.1 - 0.14 11.6 5.7 0.32 10.5 3.9 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 ETO13130.1 - 0.4 10.5 2.4 1.5 8.6 0.9 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 ETO13130.1 - 0.41 10.4 4.5 1.1 9.1 3.1 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 ETO13130.1 - 2.9 7.6 9.7 0.48 10.1 2.0 2.5 2 0 0 2 2 2 0 RING-type zinc-finger Ank_2 PF12796.2 ETO13131.1 - 1.1e-06 28.8 0.0 0.6 10.4 0.0 4.6 3 2 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO13131.1 - 2.5e-06 27.1 0.0 16 6.1 0.0 6.2 7 0 0 7 7 7 2 Ankyrin repeat Ank_4 PF13637.1 ETO13131.1 - 4.3e-05 23.9 0.0 32 5.1 0.0 5.3 5 0 0 5 5 5 1 Ankyrin repeats (many copies) DUF2992 PF11208.3 ETO13131.1 - 6.1 6.7 15.7 36 4.2 10.9 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2992) Mito_carr PF00153.22 ETO13132.1 - 1.1e-38 130.8 0.2 6.2e-24 83.5 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein zf-CCHC_2 PF13696.1 ETO13133.1 - 2.1e-10 39.8 31.7 1e-05 24.9 6.5 3.3 2 1 1 3 3 3 3 Zinc knuckle zf-CCHC PF00098.18 ETO13133.1 - 5.9e-10 38.5 16.8 0.00071 19.3 3.3 3.3 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.1 ETO13133.1 - 0.1 12.3 15.2 0.11 12.2 1.5 3.3 3 1 0 3 3 3 0 Zinc knuckle zf-CCHC_4 PF14392.1 ETO13133.1 - 0.24 11.0 14.7 1.2 8.9 1.1 3.3 2 1 1 3 3 3 0 Zinc knuckle Tnp_zf-ribbon_2 PF13842.1 ETO13133.1 - 2 8.9 8.0 1.1 9.7 0.5 2.6 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Glyoxalase_2 PF12681.2 ETO13134.1 - 3e-13 50.3 0.0 4.8e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 ETO13134.1 - 4.1e-08 33.2 0.0 1.8e-07 31.1 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 ETO13134.1 - 1.1e-06 28.6 0.0 2.6e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CfAFP PF05264.6 ETO13134.1 - 0.025 14.3 0.1 0.14 11.9 0.1 1.9 2 0 0 2 2 2 0 Choristoneura fumiferana antifreeze protein (CfAFP) HECT PF00632.20 ETO13136.1 - 1.1e-88 297.5 0.0 1.6e-88 296.9 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) CAP_GLY PF01302.20 ETO13138.1 - 5.1e-18 64.5 0.4 9.4e-18 63.6 0.3 1.5 1 0 0 1 1 1 1 CAP-Gly domain Ribosomal_60s PF00428.14 ETO13138.1 - 0.011 16.0 6.3 0.011 16.0 4.3 4.3 4 0 0 4 4 4 0 60s Acidic ribosomal protein Ras PF00071.17 ETO13139.1 - 3.5e-55 185.8 0.5 7e-55 184.8 0.4 1.5 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO13139.1 - 2.2e-18 66.9 0.3 1.6e-17 64.0 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO13139.1 - 7.6e-17 61.0 0.2 1.8e-16 59.8 0.1 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.1 ETO13139.1 - 0.00073 19.6 0.0 0.0053 16.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETO13139.1 - 0.05 13.5 0.0 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Arch_ATPase PF01637.13 ETO13139.1 - 0.063 12.9 4.4 0.21 11.2 0.0 3.1 3 0 0 3 3 3 0 Archaeal ATPase YMF19 PF02326.10 ETO13140.1 - 0.023 15.2 1.6 0.4 11.2 0.1 2.5 2 1 0 2 2 2 0 Plant ATP synthase F0 Agenet PF05641.7 ETO13141.1 - 0.014 15.5 0.6 9.8 6.4 0.0 3.2 3 0 0 3 3 3 0 Agenet domain Lipase_GDSL_2 PF13472.1 ETO13142.1 - 3.8e-06 27.1 0.3 6.5e-06 26.4 0.2 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 ETO13142.1 - 0.0065 16.3 0.2 0.0099 15.7 0.1 1.4 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase DUF2263 PF10021.4 ETO13144.1 - 4.2e-25 88.4 0.1 5.5e-22 78.3 0.0 2.3 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2263) TT_ORF1 PF02956.9 ETO13144.1 - 0.0011 17.5 0.5 0.0016 16.9 0.3 1.3 1 0 0 1 1 1 1 TT viral orf 1 DUF4253 PF14062.1 ETO13144.1 - 0.065 12.8 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) TPP_enzyme_C PF02775.16 ETO13145.1 - 1.8e-22 79.5 0.0 3.3e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 ETO13145.1 - 4.4e-12 45.9 0.0 1.2e-11 44.4 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain AMP-binding PF00501.23 ETO13146.1 - 1.8e-55 188.0 0.1 2.3e-55 187.7 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Molybdop_Fe4S4 PF04879.11 ETO13146.1 - 0.14 12.0 0.4 13 5.7 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin oxidoreductase Fe4S4 domain Hydrolase_like PF13242.1 ETO13148.1 - 4.8e-16 58.2 0.0 7.7e-16 57.5 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 ETO13148.1 - 0.00029 21.0 0.0 0.00038 20.7 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Rad21_Rec8_N PF04825.8 ETO13149.1 - 0.12 12.2 0.5 0.12 12.2 0.4 2.3 2 0 0 2 2 2 0 N terminus of Rad21 / Rec8 like protein TMEM247 PF15444.1 ETO13149.1 - 0.26 11.0 2.4 0.38 10.5 1.7 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 Rad21_Rec8 PF04824.11 ETO13150.1 - 5.8e-10 38.2 0.0 1.3e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 ETO13150.1 - 0.0051 16.4 0.1 0.0095 15.5 0.0 1.6 2 0 0 2 2 2 1 ScpA/B protein DUF4200 PF13863.1 ETO13151.1 - 0.016 15.1 6.5 0.016 15.1 4.5 4.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.7 ETO13151.1 - 0.42 10.3 29.8 0.79 9.4 0.4 2.9 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein ADIP PF11559.3 ETO13151.1 - 0.61 9.9 29.3 1.5 8.7 0.8 3.0 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 ETO13151.1 - 1.8 7.6 11.7 0.12 11.5 3.9 1.9 3 0 0 3 3 3 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 ETO13151.1 - 3.9 7.3 15.7 0.76 9.5 1.4 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DASH_Dam1 PF08653.5 ETO13151.1 - 6.2 6.6 10.2 0.57 9.9 0.8 3.1 2 1 2 4 4 4 0 DASH complex subunit Dam1 Wbp11 PF09429.5 ETO13151.1 - 6.4 6.8 24.0 2.5 8.1 1.6 3.9 2 1 1 3 3 3 0 WW domain binding protein 11 Striatin PF08232.7 ETO13151.1 - 9.1 6.5 26.5 0.56 10.5 1.6 3.0 2 1 1 3 3 3 0 Striatin family Nup54 PF13874.1 ETO13152.1 - 0.011 15.3 11.4 0.011 15.3 7.9 3.1 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 DUF1664 PF07889.7 ETO13152.1 - 0.016 15.0 1.8 0.016 15.0 1.2 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Ald_Xan_dh_C PF01315.17 ETO13152.1 - 0.068 13.2 0.2 0.76 9.8 0.1 2.3 2 0 0 2 2 2 0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain H-kinase_dim PF02895.9 ETO13152.1 - 1.2 9.4 9.3 0.75 10.1 1.7 3.2 2 2 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain RGS PF00615.14 ETO13153.1 - 6.3e-07 29.5 0.1 2.4e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 Regulator of G protein signaling domain Peptidase_S49_N PF08496.5 ETO13154.1 - 0.1 12.3 2.7 3.4 7.4 0.2 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DC_STAMP PF07782.8 ETO13154.1 - 0.11 12.0 0.7 0.19 11.3 0.5 1.3 1 0 0 1 1 1 0 DC-STAMP-like protein SAM_1 PF00536.25 ETO13155.1 - 0.017 15.3 0.0 0.044 13.9 0.0 1.8 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) zf-C2H2_2 PF12756.2 ETO13155.1 - 0.017 15.2 7.6 0.33 11.1 0.2 2.7 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 ETO13155.1 - 0.02 15.0 0.5 0.02 15.0 0.3 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding RPAP1_N PF08621.5 ETO13155.1 - 0.12 12.0 0.0 0.28 10.8 0.0 1.6 2 0 0 2 2 2 0 RPAP1-like, N-terminal zf-C2H2_7 PF15269.1 ETO13155.1 - 0.3 10.9 2.2 0.58 10.0 0.4 2.1 2 0 0 2 2 2 0 Zinc-finger zf-C2H2_4 PF13894.1 ETO13155.1 - 0.53 10.7 13.0 3 8.3 2.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 ETO13155.1 - 3.1 8.2 14.7 3.4 8.0 1.8 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 ETO13155.1 - 7.6 7.1 12.4 0.73 10.2 1.7 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF3226 PF11536.3 ETO13156.1 - 0.011 15.2 0.3 0.44 9.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3226) Sec62 PF03839.11 ETO13157.1 - 3.9 6.8 11.2 5.7 6.2 7.7 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 UBA PF00627.26 ETO13158.1 - 8.4e-05 22.2 0.2 0.00032 20.4 0.0 2.1 2 0 0 2 2 2 1 UBA/TS-N domain HTH_27 PF13463.1 ETO13158.1 - 0.0051 17.0 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain FliG_N PF14842.1 ETO13159.1 - 0.0038 17.3 0.0 2.2 8.4 0.1 2.4 2 0 0 2 2 2 2 FliG N-terminal domain DUF3578 PF12102.3 ETO13159.1 - 0.018 14.6 0.4 0.058 12.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3578) AF-4 PF05110.8 ETO13160.1 - 0.019 12.8 27.2 0.02 12.8 18.8 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF2201_N PF13203.1 ETO13160.1 - 0.13 11.3 15.0 0.16 11.1 10.4 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Zip PF02535.17 ETO13160.1 - 0.16 10.9 6.2 0.2 10.6 4.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter U79_P34 PF03064.11 ETO13160.1 - 0.19 11.1 22.2 0.24 10.9 15.4 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF106 PF01956.11 ETO13160.1 - 0.33 10.4 4.2 0.46 10.0 2.9 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF106 CT47 PF15623.1 ETO13160.1 - 0.5 10.0 16.8 0.53 9.9 11.7 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 DUF1510 PF07423.6 ETO13160.1 - 0.63 9.3 32.9 0.8 9.0 22.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Hid1 PF12722.2 ETO13160.1 - 1.4 6.4 13.2 1.4 6.5 9.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AUX_IAA PF02309.11 ETO13160.1 - 2.1 8.0 20.8 2.5 7.7 14.4 1.1 1 0 0 1 1 1 0 AUX/IAA family Hex_IIIa PF02455.11 ETO13160.1 - 2.3 6.8 8.2 2.2 6.8 5.7 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Dicty_REP PF05086.7 ETO13160.1 - 2.5 5.7 14.1 2.7 5.6 9.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ycf1 PF05758.7 ETO13160.1 - 2.8 5.5 19.7 2.7 5.5 13.6 1.1 1 0 0 1 1 1 0 Ycf1 Trypan_PARP PF05887.6 ETO13160.1 - 3 7.6 16.1 4 7.2 11.2 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) HSP90 PF00183.13 ETO13160.1 - 9.8 4.4 27.7 13 3.9 19.2 1.2 1 0 0 1 1 1 0 Hsp90 protein DUF843 PF05814.6 ETO13161.1 - 0.0028 17.3 1.2 0.0028 17.3 0.8 3.2 4 0 0 4 4 4 1 Baculovirus protein of unknown function (DUF843) MFS_1 PF07690.11 ETO13161.1 - 0.14 10.8 4.9 0.71 8.5 0.6 2.3 2 1 0 2 2 2 0 Major Facilitator Superfamily ATP-synt_8 PF00895.15 ETO13161.1 - 2 8.6 7.0 3 8.1 3.4 2.4 2 0 0 2 2 2 0 ATP synthase protein 8 DUF3169 PF11368.3 ETO13161.1 - 6.5 5.8 8.3 5.7 6.0 0.3 3.4 2 2 1 4 4 4 0 Protein of unknown function (DUF3169) Apolipoprotein PF01442.13 ETO13162.1 - 0.052 13.0 6.6 0.11 12.0 4.5 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain bZIP_2 PF07716.10 ETO13162.1 - 0.12 12.1 0.1 0.12 12.1 0.1 3.6 3 1 0 3 3 3 0 Basic region leucine zipper IncA PF04156.9 ETO13162.1 - 0.37 10.3 12.5 0.51 9.8 8.7 1.2 1 0 0 1 1 1 0 IncA protein DUF1664 PF07889.7 ETO13162.1 - 1.2 8.8 5.2 30 4.4 3.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Ribosomal_60s PF00428.14 ETO13163.1 - 0.0022 18.3 3.8 0.0042 17.4 2.7 1.5 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF572 PF04502.8 ETO13163.1 - 1.2 8.2 20.2 1.8 7.7 14.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Selenoprotein_S PF06936.6 ETO13163.1 - 1.5 8.2 8.7 2.2 7.7 6.0 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) SOBP PF15279.1 ETO13163.1 - 5.3 7.3 11.2 6.5 7.0 7.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Sigma70_ner PF04546.8 ETO13164.1 - 0.011 15.3 9.3 0.015 14.9 6.4 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF506 PF04720.7 ETO13164.1 - 0.036 13.6 4.1 0.051 13.2 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF506) VIT1 PF01988.14 ETO13164.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 VIT family GOLD_2 PF13897.1 ETO13164.1 - 0.22 11.7 6.2 0.5 10.5 4.3 1.6 1 1 0 1 1 1 0 Golgi-dynamics membrane-trafficking DUF3069 PF11269.3 ETO13164.1 - 0.23 11.5 1.5 0.37 10.8 1.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3069) Daxx PF03344.10 ETO13164.1 - 0.33 9.3 17.4 0.41 9.0 12.0 1.0 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 ETO13164.1 - 0.42 9.6 8.3 0.49 9.4 5.8 1.2 1 0 0 1 1 1 0 BUD22 Sporozoite_P67 PF05642.6 ETO13164.1 - 0.83 7.4 4.6 0.85 7.4 3.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cwf_Cwc_15 PF04889.7 ETO13164.1 - 0.87 9.2 11.9 1.1 8.9 8.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 ETO13164.1 - 1.9 6.4 8.8 2.2 6.2 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.6 ETO13164.1 - 5.6 4.9 9.0 6.8 4.6 6.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NOA36 PF06524.7 ETO13164.1 - 5.9 6.0 9.3 8.8 5.4 6.4 1.2 1 0 0 1 1 1 0 NOA36 protein RVT_1 PF00078.22 ETO13165.1 - 0.0039 16.5 0.1 0.0054 16.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 ETO13166.1 - 4.9e-09 36.3 0.1 6.9e-09 35.8 0.1 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 ETO13166.1 - 5.2e-06 25.8 0.0 6.9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain NADH_B2 PF14813.1 ETO13169.1 - 0.11 12.1 0.3 0.29 10.8 0.1 1.8 2 0 0 2 2 2 0 NADH dehydrogenase 1 beta subcomplex subunit 2 zf-LITAF-like PF10601.4 ETO13169.1 - 3.7 7.4 6.0 6.6 6.6 0.1 3.2 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain WD40 PF00400.27 ETO13171.1 - 2.6e-76 249.0 16.6 3e-12 45.9 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO13171.1 - 9.6e-12 45.0 0.1 0.00033 20.4 0.0 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO13171.1 - 9.7e-10 37.8 18.6 0.5 10.0 0.0 7.7 8 0 0 8 8 8 5 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 ETO13171.1 - 3.5e-06 25.8 0.3 0.02 13.5 0.0 4.7 1 1 3 5 5 5 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nbas_N PF15492.1 ETO13171.1 - 8.3e-06 25.0 2.4 0.0011 18.1 0.1 4.0 2 1 3 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Resistin PF06954.6 ETO13171.1 - 5.8e-05 23.2 1.7 3 8.1 0.0 4.4 3 2 2 5 5 5 2 Resistin Cytochrom_D1 PF02239.11 ETO13171.1 - 0.003 15.9 0.1 0.1 10.8 0.0 2.3 2 0 0 2 2 2 1 Cytochrome D1 heme domain DUF2963 PF11178.3 ETO13171.1 - 0.0052 16.1 0.1 3.8 7.0 0.0 5.0 6 0 0 6 6 6 1 Protein of unknown function (DUF2963) SGL PF08450.7 ETO13171.1 - 0.01 15.2 0.1 3.5 6.9 0.0 3.1 1 1 2 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region DUF1258 PF06869.7 ETO13171.1 - 0.013 14.5 0.1 0.96 8.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1258) DUF3601 PF12208.3 ETO13171.1 - 0.1 12.5 0.0 15 5.6 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3601) Proteasome_A_N PF10584.4 ETO13171.1 - 0.25 10.6 17.9 7.8 5.9 0.0 6.7 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 ETO13172.1 - 2.7e-09 36.5 0.1 6e-06 25.9 0.0 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF1771 PF08590.5 ETO13175.1 - 0.0086 16.0 3.4 0.019 14.9 2.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) DUF3439 PF11921.3 ETO13175.1 - 0.18 11.5 2.6 0.15 11.7 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Kinesin PF00225.18 ETO13176.1 - 1.1e-17 63.7 6.1 7.9e-16 57.6 0.3 2.3 2 1 0 2 2 2 2 Kinesin motor domain MIB_HERC2 PF06701.8 ETO13176.1 - 0.077 12.9 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Mib_herc2 Kinesin PF00225.18 ETO13177.1 - 2.5e-41 141.4 1.1 2.5e-41 141.4 0.7 4.9 4 2 1 5 5 5 1 Kinesin motor domain PHP PF02811.14 ETO13177.1 - 9.6e-05 22.2 0.0 0.00053 19.8 0.0 2.2 1 1 0 1 1 1 1 PHP domain Pribosyltran_N PF13793.1 ETO13177.1 - 0.032 13.9 0.4 3.6 7.3 0.0 2.6 2 0 0 2 2 2 0 N-terminal domain of ribose phosphate pyrophosphokinase Secretin_N_2 PF07655.8 ETO13177.1 - 0.29 11.5 24.5 0.13 12.6 4.5 2.7 2 0 0 2 2 2 0 Secretin N-terminal domain DUF3439 PF11921.3 ETO13178.1 - 0.58 9.9 5.1 1.2 8.8 3.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Kelch_6 PF13964.1 ETO13179.1 - 0.03 14.4 0.4 0.47 10.7 0.0 3.1 3 1 1 4 4 4 0 Kelch motif Kelch_1 PF01344.20 ETO13179.1 - 0.043 13.3 1.8 0.41 10.2 0.2 3.2 4 0 0 4 4 4 0 Kelch motif Kelch_5 PF13854.1 ETO13179.1 - 0.059 13.3 0.0 25 4.9 0.0 3.5 3 0 0 3 3 3 0 Kelch motif Arm PF00514.18 ETO13180.1 - 7.3e-08 31.9 0.0 6.2e-06 25.8 0.0 3.0 2 1 1 3 3 3 1 Armadillo/beta-catenin-like repeat IBB PF01749.15 ETO13180.1 - 0.00072 19.6 5.2 0.00072 19.6 3.6 1.7 2 0 0 2 2 2 1 Importin beta binding domain CytochromB561_N PF09786.4 ETO13181.1 - 0.066 11.6 2.8 0.08 11.3 2.0 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Astro_capsid PF03115.9 ETO13181.1 - 0.07 11.3 1.5 0.078 11.2 1.0 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor CENP-B_dimeris PF09026.5 ETO13181.1 - 0.2 11.9 6.0 0.39 10.9 4.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDV3 PF15359.1 ETO13181.1 - 0.42 10.6 8.0 1 9.4 3.1 2.2 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 DUF262 PF03235.9 ETO13181.1 - 2.6 7.9 9.5 5.6 6.8 6.3 1.8 1 1 0 1 1 1 0 Protein of unknown function DUF262 WD40 PF00400.27 ETO13182.1 - 3.6e-10 39.3 0.1 0.00014 21.6 0.0 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat WD40 PF00400.27 ETO13183.1 - 5.7e-68 222.5 32.0 4.6e-13 48.4 0.3 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat zf-TRAF PF02176.13 ETO13183.1 - 2.2e-05 24.7 3.5 2.2e-05 24.7 2.4 2.4 2 0 0 2 2 2 1 TRAF-type zinc finger Pex14_N PF04695.8 ETO13183.1 - 0.0033 17.4 2.2 0.0033 17.4 1.5 2.5 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IncA PF04156.9 ETO13183.1 - 0.73 9.3 18.5 0.17 11.4 10.5 1.6 2 0 0 2 2 2 0 IncA protein Secretin_N_2 PF07655.8 ETO13183.1 - 2.2 8.7 28.9 0.12 12.7 11.5 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain Lipase_GDSL PF00657.17 ETO13185.1 - 0.098 12.4 0.2 0.14 11.9 0.2 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase DUF4591 PF15261.1 ETO13185.1 - 0.39 10.9 10.5 0.53 10.5 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4591) tRNA_synt_1c_R2 PF04557.10 ETO13185.1 - 1.3 9.7 9.9 1.8 9.3 0.2 2.3 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 FragX_IP PF05994.6 ETO13186.1 - 1.2e-126 423.5 11.1 6.2e-73 245.9 7.8 3.5 3 1 0 3 3 3 2 Cytoplasmic Fragile-X interacting family Neur_chan_memb PF02932.11 ETO13186.1 - 0.0085 16.0 1.8 0.02 14.7 1.2 1.7 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Borrelia_P83 PF05262.6 ETO13186.1 - 0.087 11.0 21.3 0.14 10.3 14.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein LicD PF04991.8 ETO13186.1 - 4.5 7.3 14.4 4.1 7.4 3.9 3.4 3 0 0 3 3 3 0 LicD family Malate_synthase PF01274.17 ETO13187.1 - 0.0073 14.3 0.0 0.0098 13.9 0.0 1.1 1 0 0 1 1 1 1 Malate synthase PPDFL PF15060.1 ETO13188.1 - 1.1 9.2 8.8 2.2 8.2 0.1 2.7 2 1 0 2 2 2 0 Differentiation and proliferation regulator DUF812 PF05667.6 ETO13189.1 - 0.0024 16.4 7.5 0.0032 16.0 5.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Snf7 PF03357.16 ETO13189.1 - 0.016 14.6 6.8 0.027 13.8 4.7 1.3 1 0 0 1 1 1 0 Snf7 DUF342 PF03961.8 ETO13189.1 - 0.023 13.1 4.5 0.023 13.1 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FlxA PF14282.1 ETO13189.1 - 0.035 14.0 10.0 0.051 13.5 3.5 2.1 1 1 1 2 2 2 0 FlxA-like protein Baculo_PEP_C PF04513.7 ETO13189.1 - 0.049 13.4 1.3 0.082 12.7 0.9 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.3 ETO13189.1 - 0.058 10.7 7.9 0.069 10.4 5.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 ETO13189.1 - 0.061 12.4 0.4 0.07 12.2 0.2 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Helicase_IV_N PF12462.3 ETO13189.1 - 0.085 12.5 1.0 0.12 11.9 0.7 1.3 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal SIMPL PF04402.9 ETO13189.1 - 0.1 12.4 0.8 0.13 12.1 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF541) DUF4061 PF13270.1 ETO13189.1 - 0.13 12.3 3.7 0.1 12.7 1.0 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4061) OmpH PF03938.9 ETO13189.1 - 0.18 11.7 4.8 0.21 11.5 3.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) IncA PF04156.9 ETO13189.1 - 0.18 11.3 8.9 15 5.1 6.2 2.1 1 1 0 1 1 1 0 IncA protein Atg14 PF10186.4 ETO13189.1 - 0.2 10.5 7.7 0.26 10.1 5.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Phage_GPO PF05929.6 ETO13189.1 - 0.33 10.1 4.1 0.23 10.6 1.6 1.5 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Phage_GP20 PF06810.6 ETO13189.1 - 0.43 9.9 9.5 1.3 8.4 6.5 1.8 1 1 1 2 2 2 0 Phage minor structural protein GP20 V_ATPase_I PF01496.14 ETO13189.1 - 0.5 8.1 3.4 0.63 7.8 2.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Syntaxin-6_N PF09177.6 ETO13189.1 - 0.82 10.1 5.9 2.2 8.7 0.7 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal TLD PF07534.11 ETO13190.1 - 3.3e-06 27.1 0.0 5.6e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 TLD MIP-T3 PF10243.4 ETO13190.1 - 8e-05 21.3 16.2 8.8e-05 21.1 11.2 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Cwf_Cwc_15 PF04889.7 ETO13190.1 - 0.014 15.0 28.2 0.021 14.5 19.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.4 ETO13190.1 - 0.036 12.8 25.8 0.052 12.2 17.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 ETO13190.1 - 0.075 11.5 20.0 0.098 11.1 13.9 1.1 1 0 0 1 1 1 0 Daxx Family Hid1 PF12722.2 ETO13190.1 - 0.33 8.5 12.5 0.4 8.3 8.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NPR3 PF03666.8 ETO13190.1 - 0.69 8.3 14.2 1.1 7.7 9.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Ebola_NP PF05505.7 ETO13190.1 - 3.1 5.7 13.1 4.1 5.3 9.1 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein FAM60A PF15396.1 ETO13190.1 - 4 7.1 16.2 8.4 6.0 11.2 1.5 1 0 0 1 1 1 0 Protein Family FAM60A PPP4R2 PF09184.6 ETO13190.1 - 5.6 6.4 22.3 8.5 5.8 15.5 1.2 1 0 0 1 1 1 0 PPP4R2 Neur_chan_memb PF02932.11 ETO13190.1 - 9.5 6.0 10.2 16 5.2 7.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pkinase PF00069.20 ETO13191.1 - 2.7e-06 26.7 0.0 2.7e-06 26.7 0.0 1.3 1 1 1 2 2 2 1 Protein kinase domain DUF4599 PF15371.1 ETO13192.1 - 0.13 12.3 3.0 0.62 10.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4599) DUF1912 PF08930.5 ETO13192.1 - 0.49 10.5 3.3 0.98 9.5 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1912) DUF3043 PF11241.3 ETO13193.1 - 0.014 14.9 1.7 0.028 13.9 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Zip PF02535.17 ETO13193.1 - 0.98 8.3 20.2 2.6 6.9 14.0 1.8 1 1 0 1 1 1 0 ZIP Zinc transporter Apis_Csd PF11671.3 ETO13193.1 - 1.2 8.8 18.8 2.9 7.6 2.9 2.5 2 0 0 2 2 2 0 Complementary sex determiner protein DUF2370 PF10176.4 ETO13193.1 - 2.1 7.6 8.7 0.61 9.3 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) DUF3753 PF12575.3 ETO13193.1 - 2.5 7.9 7.5 4.5 7.1 1.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) FAM176 PF14851.1 ETO13193.1 - 2.6 7.6 8.8 6.3 6.4 3.9 2.4 2 0 0 2 2 2 0 FAM176 family Innate_immun PF12782.2 ETO13193.1 - 3.2 6.8 16.1 5.4 6.1 11.2 1.4 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Kei1 PF08552.6 ETO13193.1 - 6.7 6.3 9.5 0.15 11.7 1.2 2.1 2 1 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 IBB PF01749.15 ETO13194.1 - 6.6e-05 22.9 7.4 0.00013 22.0 5.1 1.6 1 1 0 1 1 1 1 Importin beta binding domain Cnd1 PF12717.2 ETO13194.1 - 0.0092 15.8 0.1 0.013 15.3 0.1 1.3 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 WD40 PF00400.27 ETO13196.1 - 1e-15 56.8 0.0 4.9e-09 35.7 0.0 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF16 PF01519.11 ETO13197.1 - 0.16 12.1 2.4 0.23 11.6 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF1517 PF07466.6 ETO13198.1 - 2.7 6.8 17.0 0.067 12.1 4.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) Plasmodium_Vir PF05795.6 ETO13199.1 - 0.65 9.1 8.8 0.9 8.6 5.5 1.6 1 1 1 2 2 2 0 Plasmodium vivax Vir protein FYDLN_acid PF09538.5 ETO13199.1 - 1.3 9.5 12.2 0.034 14.7 2.9 2.1 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Tim54 PF11711.3 ETO13199.1 - 2.3 6.7 5.8 4.9 5.6 1.5 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 PPP4R2 PF09184.6 ETO13199.1 - 5.8 6.3 18.3 0.021 14.3 5.3 2.1 2 1 0 2 2 2 0 PPP4R2 WD40 PF00400.27 ETO13200.1 - 8.2e-19 66.7 3.6 1.4e-05 24.7 0.0 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 ETO13200.1 - 0.0032 17.2 0.0 0.034 13.9 0.0 2.3 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Enterotoxin_a PF01375.12 ETO13200.1 - 0.088 12.0 1.9 0.16 11.2 1.3 1.4 1 0 0 1 1 1 0 Heat-labile enterotoxin alpha chain DEAD PF00270.24 ETO13201.1 - 0.0019 17.7 0.0 0.0087 15.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.11 ETO13201.1 - 0.025 13.8 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein COBRA1 PF06209.8 ETO13202.1 - 1.4e-06 27.2 2.9 0.0027 16.3 0.4 2.3 2 0 0 2 2 2 2 Cofactor of BRCA1 (COBRA1) Myotub-related PF06602.9 ETO13203.1 - 1.9e-66 224.2 0.1 1.9e-66 224.2 0.1 1.6 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 ETO13203.1 - 0.0082 16.3 0.7 0.021 15.0 0.0 2.1 2 1 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 ETO13203.1 - 0.02 14.4 1.8 0.028 14.0 0.0 2.2 2 1 0 2 2 2 0 Dual specificity phosphatase, catalytic domain SNAP PF14938.1 ETO13205.1 - 0.028 13.5 0.1 0.04 13.0 0.1 1.2 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP SNF2_N PF00176.18 ETO13207.1 - 1e-13 50.7 0.1 1.3e-13 50.4 0.1 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain PepSY_TM PF03929.11 ETO13208.1 - 0.49 10.8 0.0 0.49 10.8 0.0 2.5 2 0 0 2 2 2 0 PepSY-associated TM helix Aminotran_3 PF00202.16 ETO13209.1 - 2e-37 128.8 0.0 2.6e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III SP_C-Propep PF08999.5 ETO13210.1 - 2.5 7.6 5.3 5 6.6 3.7 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide ELF PF03317.8 ETO13210.1 - 3.3 6.9 8.9 8 5.6 6.2 1.6 1 0 0 1 1 1 0 ELF protein ASFV_J13L PF05568.6 ETO13210.1 - 7.1 6.1 7.5 13 5.2 5.2 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein WD40 PF00400.27 ETO13216.1 - 3.3e-61 201.1 36.2 6.6e-13 47.9 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO13216.1 - 4.8e-14 51.3 2.5 0.015 13.4 0.3 5.8 2 2 4 6 6 6 6 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO13216.1 - 2e-06 28.0 2.5 1.1e-05 25.7 1.7 2.4 1 0 0 1 1 1 1 TRAF-type zinc finger V_ATPase_I PF01496.14 ETO13216.1 - 5 4.8 10.6 7.2 4.3 7.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family WD40 PF00400.27 ETO13217.1 - 4.9e-166 533.4 60.1 2e-12 46.4 0.0 14.5 14 0 0 14 14 14 14 WD domain, G-beta repeat Gmad1 PF10647.4 ETO13217.1 - 1.5e-09 37.6 7.1 0.09 12.1 0.0 5.7 3 2 2 6 6 6 3 Lipoprotein LpqB beta-propeller domain NACHT PF05729.7 ETO13217.1 - 1.8e-08 34.2 0.0 3.8e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Cytochrom_D1 PF02239.11 ETO13217.1 - 2.8e-08 32.4 8.9 0.0079 14.5 0.1 4.8 3 1 3 6 6 6 4 Cytochrome D1 heme domain AAA_18 PF13238.1 ETO13217.1 - 7.2e-05 23.1 2.8 7.2e-05 23.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETO13217.1 - 0.00077 19.6 0.0 0.002 18.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO13217.1 - 0.00082 20.1 0.2 0.0053 17.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Resistin PF06954.6 ETO13217.1 - 0.0017 18.5 15.0 1.4 9.2 0.1 6.3 6 1 1 7 7 7 2 Resistin Pentapeptide PF00805.17 ETO13217.1 - 0.029 13.5 0.1 0.082 12.1 0.1 1.7 1 1 0 1 1 1 0 Pentapeptide repeats (8 copies) PD40 PF07676.7 ETO13217.1 - 2.3 7.9 25.4 20 4.9 0.0 8.4 10 0 0 10 10 10 0 WD40-like Beta Propeller Repeat MIP-T3 PF10243.4 ETO13218.1 - 0.13 10.6 69.5 0.24 9.8 48.2 1.5 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Nop14 PF04147.7 ETO13218.1 - 0.67 7.8 45.8 0.91 7.3 31.7 1.3 1 0 0 1 1 1 0 Nop14-like family PDZ PF00595.19 ETO13219.1 - 6.4e-09 35.8 0.3 0.00042 20.4 0.1 2.3 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 ETO13219.1 - 0.00015 21.6 0.7 0.031 14.1 0.3 2.2 1 1 1 2 2 2 2 PDZ domain DUF3753 PF12575.3 ETO13220.1 - 0.023 14.5 1.5 0.023 14.5 1.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3753) Laminin_G_3 PF13385.1 ETO13220.1 - 0.095 12.9 3.7 0.1 12.8 1.7 1.4 1 1 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily DUF912 PF06024.7 ETO13220.1 - 1.4 8.9 7.6 0.46 10.5 0.4 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Erythro_esteras PF05139.9 ETO13221.1 - 0.013 14.7 3.4 0.017 14.3 2.4 1.1 1 0 0 1 1 1 0 Erythromycin esterase TRAP_alpha PF03896.11 ETO13221.1 - 0.016 14.1 7.2 0.026 13.5 5.0 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Daxx PF03344.10 ETO13221.1 - 0.021 13.3 13.4 0.025 13.1 9.3 1.2 1 0 0 1 1 1 0 Daxx Family DUF2890 PF11081.3 ETO13221.1 - 0.045 13.8 10.8 0.062 13.3 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) TFIIF_alpha PF05793.7 ETO13221.1 - 0.064 11.6 15.9 0.079 11.3 11.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Sporozoite_P67 PF05642.6 ETO13221.1 - 0.077 10.8 4.1 0.09 10.6 2.8 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3438 PF11920.3 ETO13221.1 - 0.089 11.6 0.2 0.1 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) CDC45 PF02724.9 ETO13221.1 - 0.093 10.7 11.0 0.13 10.2 7.6 1.3 1 0 0 1 1 1 0 CDC45-like protein CENP-T PF15511.1 ETO13221.1 - 0.13 11.4 5.8 0.17 11.0 4.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T VID27 PF08553.5 ETO13221.1 - 0.14 10.3 14.0 0.17 10.0 9.7 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Pilt PF15453.1 ETO13221.1 - 0.18 11.4 8.6 0.26 10.9 6.0 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions DDHD PF02862.12 ETO13221.1 - 0.31 10.7 5.7 0.49 10.1 4.0 1.3 1 0 0 1 1 1 0 DDHD domain DUF2457 PF10446.4 ETO13221.1 - 0.64 8.6 15.3 0.84 8.2 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pox_Ag35 PF03286.9 ETO13221.1 - 0.68 9.4 10.9 1 8.8 7.5 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Prog_receptor PF02161.10 ETO13221.1 - 0.68 8.6 2.5 0.77 8.5 1.7 1.1 1 0 0 1 1 1 0 Progesterone receptor OAD_gamma PF04277.8 ETO13221.1 - 0.74 10.2 5.7 1.9 8.8 3.9 1.7 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Astro_capsid PF03115.9 ETO13221.1 - 0.74 8.0 5.8 0.76 7.9 4.0 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor RRN3 PF05327.6 ETO13221.1 - 1 7.4 18.4 0.14 10.2 8.9 1.9 1 1 1 3 3 3 0 RNA polymerase I specific transcription initiation factor RRN3 Usp PF00582.21 ETO13221.1 - 1.2 9.3 4.1 1.8 8.7 2.8 1.3 1 0 0 1 1 1 0 Universal stress protein family YqfQ PF14181.1 ETO13221.1 - 1.4 8.9 10.9 2.8 7.9 7.5 1.5 1 0 0 1 1 1 0 YqfQ-like protein RNA_pol_3_Rpc31 PF11705.3 ETO13221.1 - 1.8 8.4 17.9 2.7 7.8 12.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Myc_N PF01056.13 ETO13221.1 - 2.1 7.4 14.1 3.3 6.7 9.8 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Nucleoside_tran PF01733.13 ETO13221.1 - 2.8 7.0 5.2 5.4 6.0 3.6 1.4 1 0 0 1 1 1 0 Nucleoside transporter Nucleoplasmin PF03066.10 ETO13221.1 - 2.8 7.4 20.5 4.5 6.7 14.2 1.4 1 0 0 1 1 1 0 Nucleoplasmin IncA PF04156.9 ETO13221.1 - 4.4 6.8 12.2 6.5 6.2 8.5 1.3 1 0 0 1 1 1 0 IncA protein CENP-B_dimeris PF09026.5 ETO13221.1 - 4.4 7.5 17.4 10 6.4 12.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ycf1 PF05758.7 ETO13221.1 - 4.9 4.7 20.3 2.2 5.8 10.9 1.8 1 1 1 2 2 2 0 Ycf1 Aa_trans PF01490.13 ETO13222.1 - 1.4e-36 125.9 22.2 4.6e-36 124.1 15.4 1.8 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 ETO13222.1 - 0.28 9.9 13.6 0.046 12.5 6.2 1.9 2 1 0 2 2 2 0 Tryptophan/tyrosine permease family Aa_trans PF01490.13 ETO13223.1 - 1e-08 34.1 5.2 1e-08 34.1 3.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CAP_GLY PF01302.20 ETO13224.1 - 3.1e-10 39.5 0.4 5.6e-10 38.7 0.3 1.4 1 0 0 1 1 1 1 CAP-Gly domain CDC45 PF02724.9 ETO13224.1 - 1.7 6.5 26.3 2.8 5.8 18.2 1.3 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 ETO13224.1 - 1.9 7.6 33.9 3.1 6.9 23.5 1.3 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 ETO13224.1 - 5 5.4 37.1 1.1 7.6 23.3 1.6 1 1 0 2 2 2 0 Daxx Family FANCI_S4 PF14678.1 ETO13225.1 - 0.00077 18.6 0.8 0.00088 18.4 0.6 1.1 1 0 0 1 1 1 1 FANCI solenoid 4 Baculo_PEP_C PF04513.7 ETO13225.1 - 0.0024 17.6 0.2 0.003 17.3 0.1 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Fe-S_assembly PF04384.8 ETO13225.1 - 0.058 13.7 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 Iron-sulphur cluster assembly Mer2 PF09074.5 ETO13225.1 - 0.089 12.7 2.1 0.14 12.0 1.3 1.4 1 1 0 1 1 1 0 Mer2 RelA_SpoT PF04607.12 ETO13225.1 - 0.11 12.5 1.9 1.4 8.9 0.1 2.2 1 1 1 2 2 2 0 Region found in RelA / SpoT proteins DUF3384 PF11864.3 ETO13226.1 - 0.5 8.7 20.0 0.57 8.5 13.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) TPR_MLP1_2 PF07926.7 ETO13227.1 - 0.0047 16.6 13.2 0.0047 16.6 9.1 2.1 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein Med2 PF11214.3 ETO13227.1 - 0.026 14.5 1.5 0.026 14.5 1.0 3.1 1 1 2 3 3 2 0 Mediator complex subunit 2 Tropomyosin_1 PF12718.2 ETO13227.1 - 0.2 11.4 31.1 0.12 12.2 2.5 2.3 1 1 1 2 2 2 0 Tropomyosin like Plasmid_killer PF05015.8 ETO13227.1 - 0.31 11.2 3.8 0.22 11.7 0.8 2.1 1 1 0 2 2 2 0 Plasmid maintenance system killer protein RVT_connect PF06815.8 ETO13227.1 - 0.55 10.1 6.3 0.16 11.8 0.6 2.5 1 1 2 3 3 3 0 Reverse transcriptase connection domain NPV_P10 PF05531.7 ETO13227.1 - 0.56 10.5 6.5 1.6 9.0 1.8 2.9 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein HlyD PF00529.15 ETO13227.1 - 0.63 9.2 10.2 0.71 9.1 7.1 1.1 1 0 0 1 1 1 0 HlyD family secretion protein HCR PF07111.7 ETO13227.1 - 0.88 7.4 22.2 2.1 6.2 15.4 1.5 1 1 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) DUF4618 PF15397.1 ETO13227.1 - 1 8.6 25.5 0.11 11.7 9.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) DUF1777 PF08648.7 ETO13227.1 - 1.3 8.7 6.8 2.3 7.8 4.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) Fib_alpha PF08702.5 ETO13227.1 - 1.5 8.9 15.4 1 9.4 8.5 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FliD_C PF07195.7 ETO13227.1 - 2 7.6 9.5 3.1 7.0 6.2 1.6 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus PLRV_ORF5 PF01690.12 ETO13227.1 - 3.1 6.8 6.6 3.5 6.6 4.6 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Mgr1 PF08602.5 ETO13227.1 - 5.5 5.8 14.5 3.3 6.6 6.7 1.9 1 1 1 2 2 2 0 Mgr1-like, i-AAA protease complex subunit Evr1_Alr PF04777.8 ETO13228.1 - 5.9e-28 96.6 0.5 1.1e-27 95.7 0.4 1.5 1 0 0 1 1 1 1 Erv1 / Alr family PhdYeFM_antitox PF02604.14 ETO13229.1 - 0.0064 16.0 3.0 0.029 13.9 1.1 2.3 2 0 0 2 2 2 1 Antitoxin Phd_YefM, type II toxin-antitoxin system Rrp15p PF07890.7 ETO13229.1 - 5 7.1 21.2 1.5 8.9 12.1 2.0 2 0 0 2 2 2 0 Rrp15p Pox_Ag35 PF03286.9 ETO13230.1 - 0.0015 18.1 4.8 0.0036 16.8 3.3 1.6 1 0 0 1 1 1 1 Pox virus Ag35 surface protein Zip PF02535.17 ETO13230.1 - 0.014 14.4 25.8 0.06 12.3 2.7 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter DUF3464 PF11947.3 ETO13230.1 - 0.18 11.2 3.0 0.45 9.9 2.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF4407 PF14362.1 ETO13230.1 - 0.62 8.9 3.6 1.1 8.1 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pex16 PF08610.5 ETO13232.1 - 4.4e-20 71.9 0.3 5.6e-20 71.6 0.2 1.1 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Hormone_1 PF00103.15 ETO13232.1 - 0.013 14.8 0.0 0.028 13.7 0.0 1.5 1 0 0 1 1 1 0 Somatotropin hormone family Pkinase PF00069.20 ETO13233.1 - 0.00026 20.2 1.8 0.00048 19.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Nucleoplasmin PF03066.10 ETO13233.1 - 0.03 13.8 6.1 0.044 13.2 3.8 1.6 2 0 0 2 2 2 0 Nucleoplasmin Prog_receptor PF02161.10 ETO13233.1 - 0.084 11.6 4.0 0.099 11.4 2.8 1.0 1 0 0 1 1 1 0 Progesterone receptor PRP21_like_P PF12230.3 ETO13233.1 - 0.12 11.8 11.7 0.15 11.5 8.1 1.3 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein Hex_IIIa PF02455.11 ETO13233.1 - 0.27 9.8 4.6 0.33 9.5 3.2 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) CDC45 PF02724.9 ETO13233.1 - 0.33 8.9 8.3 0.37 8.7 5.8 1.0 1 0 0 1 1 1 0 CDC45-like protein VID27 PF08553.5 ETO13233.1 - 0.34 9.0 8.3 0.39 8.8 5.8 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein FAM176 PF14851.1 ETO13233.1 - 0.52 9.9 9.8 0.88 9.2 6.8 1.3 1 0 0 1 1 1 0 FAM176 family Asp-B-Hydro_N PF05279.6 ETO13233.1 - 0.54 10.0 12.9 0.65 9.8 9.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DDRGK PF09756.4 ETO13233.1 - 0.7 9.2 17.5 1.1 8.6 12.1 1.2 1 0 0 1 1 1 0 DDRGK domain Ycf1 PF05758.7 ETO13233.1 - 0.86 7.2 10.3 0.98 7.0 7.2 1.0 1 0 0 1 1 1 0 Ycf1 DUF1510 PF07423.6 ETO13233.1 - 1.1 8.5 14.8 1.5 8.1 10.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DHHW PF14286.1 ETO13233.1 - 2 7.6 8.6 2.7 7.2 5.9 1.1 1 0 0 1 1 1 0 DHHW protein Peptidase_S64 PF08192.6 ETO13233.1 - 3.1 6.0 7.8 3.4 5.9 5.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 HSP70 PF00012.15 ETO13233.1 - 3.6 5.3 10.3 4.4 5.0 7.1 1.1 1 0 0 1 1 1 0 Hsp70 protein TP53IP5 PF15331.1 ETO13233.1 - 4.8 7.0 9.4 6 6.7 6.5 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Mem_trans PF03547.13 ETO13233.1 - 5.6 5.1 7.3 6.5 4.9 5.0 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF4637 PF15470.1 ETO13233.1 - 5.7 6.5 11.6 7.2 6.2 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF3464 PF11947.3 ETO13233.1 - 6.6 6.1 6.2 8.7 5.7 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Ndc1_Nup PF09531.5 ETO13233.1 - 6.7 4.9 5.5 7.4 4.8 3.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Sec62 PF03839.11 ETO13233.1 - 9.2 5.6 8.7 13 5.1 6.0 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 PBP1_TM PF14812.1 ETO13233.1 - 9.8 6.5 9.1 18 5.7 6.3 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA PF00004.24 ETO13234.1 - 1.1e-11 45.1 0.0 1.3e-10 41.5 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 ETO13234.1 - 0.00021 20.7 0.0 0.00044 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETO13234.1 - 0.00025 21.1 0.0 0.0008 19.4 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 ETO13234.1 - 0.0011 19.1 0.0 0.0051 16.9 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ETO13234.1 - 0.011 16.6 0.0 0.034 14.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 ETO13234.1 - 0.014 14.4 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 ETO13234.1 - 0.015 14.9 0.0 0.058 13.0 0.0 2.0 1 1 0 1 1 1 0 NACHT domain AAA_29 PF13555.1 ETO13234.1 - 0.019 14.5 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.13 ETO13234.1 - 0.026 14.0 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.1 ETO13234.1 - 0.034 14.4 0.0 0.1 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 ETO13234.1 - 0.063 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 ETO13234.1 - 0.065 13.1 0.2 0.23 11.3 0.0 2.0 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 ETO13234.1 - 0.068 13.3 0.0 0.5 10.5 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.1 ETO13234.1 - 0.07 13.4 0.0 0.21 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 ETO13234.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) UNC-93 PF05978.11 ETO13234.1 - 0.71 9.3 5.6 0.097 12.1 0.6 1.9 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 Peptidase_C48 PF02902.14 ETO13235.1 - 3.2e-26 92.2 10.0 5.2e-26 91.6 6.9 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain B2-adapt-app_C PF09066.5 ETO13235.1 - 0.0098 15.7 0.8 0.018 14.8 0.6 1.4 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain RGS PF00615.14 ETO13236.1 - 1e-11 44.9 1.4 1.9e-11 44.0 0.0 2.3 2 1 0 2 2 2 1 Regulator of G protein signaling domain RskA PF10099.4 ETO13236.1 - 0.0092 15.7 1.0 0.021 14.5 0.7 1.6 1 0 0 1 1 1 1 Anti-sigma-K factor rskA GlutR_dimer PF00745.15 ETO13237.1 - 0.0042 16.9 0.5 0.0065 16.3 0.3 1.5 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain ADH_zinc_N_2 PF13602.1 ETO13238.1 - 1.9e-12 48.1 0.0 3.8e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETO13238.1 - 2.7e-10 39.9 0.1 1.7e-08 34.2 0.0 3.1 2 2 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETO13238.1 - 1.6e-09 37.3 0.4 1.9e-06 27.4 0.0 2.6 3 0 0 3 3 3 2 Zinc-binding dehydrogenase WD40 PF00400.27 ETO13239.1 - 8.8e-37 123.6 25.1 5.2e-09 35.6 0.9 6.2 4 2 1 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO13239.1 - 8.2e-07 27.5 1.8 0.00079 17.6 0.4 2.7 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Exostosin PF03016.10 ETO13240.1 - 1.1e-25 90.2 0.0 1.5e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 Exostosin family Exostosin PF03016.10 ETO13242.1 - 0.09 11.8 0.3 0.18 10.8 0.2 1.6 1 1 0 1 1 1 0 Exostosin family NTF-like PF14540.1 ETO13243.1 - 0.0067 16.0 0.1 0.017 14.6 0.1 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase-like PDEase_I_N PF08499.7 ETO13243.1 - 0.015 15.1 0.2 0.049 13.5 0.1 1.9 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal PTPlike_phytase PF14566.1 ETO13244.1 - 3.2e-23 82.4 0.4 1.2e-22 80.5 0.0 2.1 2 0 0 2 2 2 1 Inositol hexakisphosphate Neur_chan_memb PF02932.11 ETO13244.1 - 0.00023 21.1 4.2 0.00023 21.1 2.9 3.1 2 1 1 3 3 3 1 Neurotransmitter-gated ion-channel transmembrane region DSPc PF00782.15 ETO13244.1 - 0.044 13.3 0.0 0.14 11.7 0.0 1.8 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF1948 PF09185.5 ETO13244.1 - 0.051 13.2 0.3 0.13 11.9 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1948) Y_phosphatase3 PF13350.1 ETO13244.1 - 0.055 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family Daxx PF03344.10 ETO13247.1 - 0.0035 15.9 16.6 0.0065 15.0 11.5 1.4 1 0 0 1 1 1 1 Daxx Family Band_3_cyto PF07565.8 ETO13247.1 - 0.0084 15.6 6.8 0.029 13.8 0.6 2.3 2 0 0 2 2 2 2 Band 3 cytoplasmic domain DUF1053 PF06327.9 ETO13247.1 - 0.094 13.0 5.5 0.37 11.1 0.2 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) CENP-B_dimeris PF09026.5 ETO13247.1 - 0.63 10.3 9.7 0.69 10.1 3.1 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain TRAP_alpha PF03896.11 ETO13247.1 - 0.97 8.3 11.7 3.1 6.7 0.3 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit VID27 PF08553.5 ETO13247.1 - 1.6 6.8 10.0 0.049 11.8 0.8 2.0 2 0 0 2 2 2 0 VID27 cytoplasmic protein Tub PF01167.13 ETO13248.1 - 0.14 11.1 0.7 0.16 10.9 0.5 1.1 1 0 0 1 1 1 0 Tub family Band_3_cyto PF07565.8 ETO13248.1 - 0.51 9.8 3.6 0.53 9.7 2.1 1.3 1 1 0 1 1 1 0 Band 3 cytoplasmic domain Spore_coat_CotO PF14153.1 ETO13249.1 - 4.6 6.6 10.3 7.6 5.9 7.1 1.3 1 0 0 1 1 1 0 Spore coat protein CotO NDT80_PhoG PF05224.7 ETO13251.1 - 0.66 9.9 9.0 0.76 9.7 5.7 1.4 1 1 0 1 1 1 0 NDT80 / PhoG like DNA-binding family Anticodon_1 PF08264.8 ETO13252.1 - 0.022 14.5 1.3 0.044 13.5 0.9 1.5 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA ApoLp-III PF07464.6 ETO13253.1 - 0.0035 17.3 7.2 0.14 12.1 4.2 2.3 2 1 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) CPSase_L_D3 PF02787.14 ETO13253.1 - 0.007 16.1 0.2 0.025 14.3 0.0 1.9 1 1 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain AAA_13 PF13166.1 ETO13253.1 - 0.026 13.0 14.0 0.035 12.5 9.7 1.1 1 0 0 1 1 1 0 AAA domain DUF2600 PF10776.4 ETO13253.1 - 0.035 12.9 0.5 0.053 12.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2600) DUF2935 PF11155.3 ETO13253.1 - 0.13 12.3 2.5 0.21 11.7 1.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) Ribonuc_2-5A PF06479.7 ETO13253.1 - 0.28 11.0 2.6 0.33 10.8 1.1 1.6 1 1 0 1 1 1 0 Ribonuclease 2-5A TMPIT PF07851.8 ETO13253.1 - 0.72 8.8 7.4 1 8.3 5.2 1.4 1 0 0 1 1 1 0 TMPIT-like protein LUC7 PF03194.10 ETO13253.1 - 1.1 8.7 8.6 1.7 8.1 6.0 1.3 1 0 0 1 1 1 0 LUC7 N_terminus Laminin_II PF06009.7 ETO13253.1 - 1.8 8.3 7.2 1.3 8.8 3.6 1.8 1 1 0 1 1 1 0 Laminin Domain II Syntaxin-6_N PF09177.6 ETO13253.1 - 3.8 7.9 7.7 1.2 9.5 1.9 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal CTDII PF01556.13 ETO13254.1 - 1.6e-09 37.5 0.0 4.6e-09 36.0 0.0 1.7 2 0 0 2 2 2 1 DnaJ C terminal domain PKI PF02827.11 ETO13254.1 - 0.077 13.1 0.2 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor DnaJ_CXXCXGXG PF00684.14 ETO13255.1 - 0.00016 21.6 3.7 0.19 11.8 0.4 2.5 2 0 0 2 2 2 2 DnaJ central domain ELL PF10390.4 ETO13258.1 - 0.05 12.8 2.2 0.041 13.1 0.7 1.3 1 1 1 2 2 2 0 RNA polymerase II elongation factor ELL zf-RING_2 PF13639.1 ETO13259.1 - 0.011 15.5 1.8 1.8 8.4 1.2 2.5 1 1 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.1 ETO13259.1 - 0.015 14.7 0.4 1.3 8.6 0.0 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 CpXC PF14353.1 ETO13259.1 - 0.053 13.4 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 CpXC protein Zn-ribbon_8 PF09723.5 ETO13259.1 - 0.1 12.5 0.1 0.27 11.2 0.1 1.7 1 0 0 1 1 1 0 Zinc ribbon domain MIF PF01187.13 ETO13259.1 - 0.11 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Macrophage migration inhibitory factor (MIF) PsbI PF02532.9 ETO13259.1 - 0.28 10.8 2.5 0.59 9.7 1.2 1.8 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) DUF3449 PF11931.3 ETO13260.1 - 0.027 13.9 0.7 0.048 13.1 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) TRAP_alpha PF03896.11 ETO13261.1 - 0.00098 18.2 3.7 0.0012 17.9 2.6 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit BSP_II PF05432.6 ETO13261.1 - 0.0021 17.4 11.2 0.0028 16.9 7.7 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) DUF21 PF01595.15 ETO13261.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF21 Bac_luciferase PF00296.15 ETO13261.1 - 0.027 13.5 0.1 0.027 13.5 0.1 1.1 1 0 0 1 1 1 0 Luciferase-like monooxygenase Cytomega_UL84 PF06284.6 ETO13261.1 - 0.041 12.2 0.2 0.045 12.1 0.1 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein SDA1 PF05285.7 ETO13261.1 - 0.055 12.7 3.5 0.052 12.8 2.4 1.0 1 0 0 1 1 1 0 SDA1 FAM176 PF14851.1 ETO13261.1 - 0.075 12.7 1.3 0.093 12.4 0.9 1.2 1 0 0 1 1 1 0 FAM176 family Nucleoplasmin PF03066.10 ETO13261.1 - 0.16 11.4 15.0 0.22 11.0 10.4 1.2 1 0 0 1 1 1 0 Nucleoplasmin Mak16 PF04874.9 ETO13261.1 - 0.16 12.0 12.8 0.22 11.6 8.9 1.2 1 0 0 1 1 1 0 Mak16 protein C-terminal region Pox_Ag35 PF03286.9 ETO13261.1 - 0.19 11.2 4.2 0.23 10.9 2.9 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Sigma70_ner PF04546.8 ETO13261.1 - 0.77 9.3 10.4 0.99 8.9 7.2 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF1510 PF07423.6 ETO13261.1 - 0.92 8.8 10.3 1.3 8.3 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) AF1Q PF15017.1 ETO13261.1 - 1.3 8.9 9.6 1.9 8.4 6.7 1.3 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator RXT2_N PF08595.6 ETO13261.1 - 1.3 8.7 8.2 1.8 8.3 5.7 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal Pox_RNA_Pol_19 PF05320.7 ETO13261.1 - 1.9 8.2 7.9 2.6 7.7 5.5 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit NOA36 PF06524.7 ETO13261.1 - 2.1 7.5 12.2 2.6 7.2 8.5 1.1 1 0 0 1 1 1 0 NOA36 protein Prp19_bind PF06991.6 ETO13261.1 - 3.3 6.9 11.7 3.8 6.7 8.1 1.1 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain DUF2457 PF10446.4 ETO13261.1 - 3.4 6.2 18.1 4.2 5.9 12.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) HSP90 PF00183.13 ETO13261.1 - 3.6 5.8 9.7 4.3 5.6 6.8 1.0 1 0 0 1 1 1 0 Hsp90 protein DUF4611 PF15387.1 ETO13261.1 - 4.6 7.4 11.5 7 6.8 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.5 ETO13261.1 - 6.1 7.1 20.0 9.6 6.5 13.9 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain VID27 PF08553.5 ETO13261.1 - 6.5 4.8 9.4 7.4 4.6 6.5 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein NnrU PF07298.6 ETO13262.1 - 0.013 14.9 0.1 0.017 14.5 0.1 1.1 1 0 0 1 1 1 0 NnrU protein UBA PF00627.26 ETO13263.1 - 2.7e-07 30.2 0.0 4.5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain Phosphodiest PF01663.17 ETO13264.1 - 4.2e-26 92.1 0.2 5.4e-26 91.7 0.1 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 ETO13264.1 - 0.018 14.2 0.1 0.02 14.0 0.1 1.2 1 0 0 1 1 1 0 Sulfatase Metalloenzyme PF01676.13 ETO13264.1 - 0.04 13.3 0.3 0.85 8.9 0.1 2.0 2 0 0 2 2 2 0 Metalloenzyme superfamily DUF229 PF02995.12 ETO13264.1 - 0.16 10.3 0.1 0.18 10.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) fn3 PF00041.16 ETO13265.1 - 2e-08 34.2 0.6 5.2e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 Fibronectin type III domain DUF572 PF04502.8 ETO13265.1 - 0.2 10.8 38.0 0.3 10.2 26.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Utp14 PF04615.8 ETO13267.1 - 0.31 9.1 16.4 0.58 8.2 11.4 1.5 1 0 0 1 1 1 0 Utp14 protein Pneumo_matrix PF03393.11 ETO13268.1 - 0.07 12.0 0.0 1.4 7.8 0.0 2.2 2 0 0 2 2 2 0 Pneumovirus matrix protein Tudor-knot PF11717.3 ETO13268.1 - 0.13 12.0 4.0 0.35 10.5 1.4 2.5 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain Laminin_G_3 PF13385.1 ETO13269.1 - 0.00014 22.1 0.0 0.00021 21.5 0.0 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PAP_RNA-bind PF04926.10 ETO13269.1 - 0.1 12.1 2.1 0.3 10.5 1.4 1.9 1 1 1 2 2 2 0 Poly(A) polymerase predicted RNA binding domain EspG PF06872.6 ETO13271.1 - 0.042 12.1 0.1 0.052 11.8 0.0 1.1 1 0 0 1 1 1 0 EspG protein Chordopox_A13L PF05961.6 ETO13272.1 - 0.5 10.3 3.5 10 6.1 0.4 2.6 2 0 0 2 2 2 0 Chordopoxvirus A13L protein TLD PF07534.11 ETO13273.1 - 6.6e-16 58.5 0.0 8.2e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 TLD BCAS2 PF05700.6 ETO13274.1 - 9.3e-33 113.5 19.8 9.3e-33 113.5 13.7 1.3 2 0 0 2 2 2 1 Breast carcinoma amplified sequence 2 (BCAS2) DUF342 PF03961.8 ETO13274.1 - 3.9 5.7 7.7 4.9 5.4 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Pkinase PF00069.20 ETO13275.1 - 5e-38 130.7 3.7 6.7e-36 123.7 1.1 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO13275.1 - 2e-20 72.9 0.3 2.5e-13 49.6 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase CIAPIN1 PF05093.8 ETO13275.1 - 2.2 8.3 5.9 0.35 10.9 0.6 2.1 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis CBS PF00571.23 ETO13276.1 - 1.6e-17 62.9 0.0 3.8e-05 23.3 0.0 3.2 3 0 0 3 3 3 3 CBS domain GHMP_kinases_N PF00288.21 ETO13277.1 - 9.7e-05 22.3 0.2 0.00019 21.4 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain Pox_Ag35 PF03286.9 ETO13277.1 - 0.2 11.1 4.5 0.32 10.5 3.1 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2457 PF10446.4 ETO13277.1 - 0.4 9.3 13.4 0.53 8.9 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) VID27 PF08553.5 ETO13277.1 - 0.98 7.5 7.0 1.2 7.2 4.9 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein CDC45 PF02724.9 ETO13277.1 - 1.7 6.5 7.2 2.1 6.3 5.0 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.1 ETO13277.1 - 2.8 8.2 13.1 5.6 7.3 9.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.7 ETO13277.1 - 3 5.6 9.5 3.8 5.3 6.6 1.1 1 0 0 1 1 1 0 Nop14-like family FAM183 PF14886.1 ETO13278.1 - 1.2e-09 38.5 2.4 1.2e-09 38.5 1.7 2.1 2 1 0 2 2 2 1 FAM183A and FAM183B related PH PF00169.24 ETO13279.1 - 4.4e-08 33.2 0.7 1.2e-07 31.9 0.0 2.0 2 0 0 2 2 2 1 PH domain FYVE PF01363.16 ETO13279.1 - 0.0022 17.8 0.5 0.0051 16.6 0.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger IncA PF04156.9 ETO13279.1 - 0.0034 16.9 1.2 0.0034 16.9 0.8 2.0 2 0 0 2 2 2 1 IncA protein DUF1625 PF07787.7 ETO13279.1 - 0.05 12.8 0.4 0.1 11.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) RhoGEF PF00621.15 ETO13279.1 - 0.07 13.0 0.2 0.07 13.0 0.2 1.9 2 0 0 2 2 2 0 RhoGEF domain bZIP_2 PF07716.10 ETO13279.1 - 0.094 12.5 10.0 0.038 13.8 3.6 2.7 2 0 0 2 2 2 0 Basic region leucine zipper DMPK_coil PF08826.5 ETO13279.1 - 1.2 9.0 8.5 0.38 10.6 1.9 2.4 2 0 0 2 2 2 0 DMPK coiled coil domain like DivIC PF04977.10 ETO13279.1 - 5.2 6.6 15.2 0.35 10.3 3.0 3.2 3 0 0 3 3 3 0 Septum formation initiator DUF904 PF06005.7 ETO13279.1 - 8.3 6.7 15.6 0.97 9.7 7.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF904) SNF2_N PF00176.18 ETO13280.1 - 8.5e-59 198.7 4.7 4.8e-58 196.3 3.2 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETO13280.1 - 2e-12 46.7 0.1 9.9e-12 44.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Arm PF00514.18 ETO13281.1 - 0.0064 16.2 0.1 0.019 14.8 0.0 1.8 1 0 0 1 1 1 1 Armadillo/beta-catenin-like repeat zf-AD PF07776.10 ETO13281.1 - 0.023 14.6 1.0 0.086 12.8 0.4 2.2 1 1 1 2 2 2 0 Zinc-finger associated domain (zf-AD) HEAT PF02985.17 ETO13281.1 - 0.11 12.6 0.2 1.2 9.4 0.0 2.7 2 0 0 2 2 2 0 HEAT repeat MpPF26 PF07666.6 ETO13282.1 - 0.015 15.1 9.5 0.027 14.3 6.6 1.3 1 0 0 1 1 1 0 M penetrans paralogue family 26 Lig_chan PF00060.21 ETO13282.1 - 0.17 11.6 1.5 0.15 11.7 0.2 1.5 2 0 0 2 2 2 0 Ligand-gated ion channel DUF2975 PF11188.3 ETO13282.1 - 0.29 10.8 8.8 0.18 11.5 2.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2975) UvrD-helicase PF00580.16 ETO13283.1 - 3.4e-39 134.9 6.4 5.4e-39 134.3 4.4 1.2 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 ETO13283.1 - 1.5e-24 87.1 0.2 1.5e-24 87.1 0.1 2.4 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain IF2_N PF04760.10 ETO13283.1 - 0.014 15.0 0.3 0.69 9.6 0.0 2.8 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region PTS_IIA PF02255.11 ETO13283.1 - 0.1 12.4 2.2 0.27 11.1 1.2 2.0 1 1 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit UvrD_C PF13361.1 ETO13284.1 - 2.1e-37 129.4 0.5 3.1e-37 128.8 0.4 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.1 ETO13284.1 - 6.5e-11 42.3 0.0 4.9e-05 23.4 0.0 2.5 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 ETO13284.1 - 0.053 13.0 0.1 12 5.3 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF3281 PF11685.3 ETO13284.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3281) Ferrochelatase PF00762.14 ETO13285.1 - 0.05 12.5 0.0 0.081 11.8 0.0 1.2 1 0 0 1 1 1 0 Ferrochelatase Daxx PF03344.10 ETO13285.1 - 0.067 11.6 28.4 0.096 11.1 19.7 1.3 1 0 0 1 1 1 0 Daxx Family CobT PF06213.7 ETO13285.1 - 0.64 9.0 20.4 1.2 8.2 14.2 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT eIF-3c_N PF05470.7 ETO13285.1 - 1.9 6.4 26.1 0.31 9.0 14.5 1.9 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Herpes_LMP1 PF05297.6 ETO13285.1 - 4.6 6.0 10.5 6.5 5.5 7.3 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) zf-H2C2_2 PF13465.1 ETO13287.1 - 3.2e-13 49.2 12.5 1.9e-05 24.6 0.1 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 ETO13287.1 - 1.7e-09 37.4 15.4 0.0012 19.0 0.1 4.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 ETO13287.1 - 6.4e-05 22.9 15.0 0.00034 20.6 1.0 4.0 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 ETO13287.1 - 6.8e-05 22.9 8.8 0.0042 17.1 0.5 2.7 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 ETO13287.1 - 7.3e-05 22.8 17.9 0.17 12.2 2.2 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-RING_3 PF14369.1 ETO13287.1 - 0.0035 17.2 4.9 0.021 14.7 0.1 3.3 4 0 0 4 4 4 1 zinc-finger zf-C2H2_6 PF13912.1 ETO13287.1 - 0.015 15.2 14.1 0.04 13.8 1.4 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.2 ETO13287.1 - 0.016 15.3 7.4 0.46 10.7 1.4 3.3 3 0 0 3 3 2 0 Zinc-finger of C2H2 type C1_1 PF00130.17 ETO13287.1 - 0.022 14.5 13.0 0.71 9.6 0.5 3.7 3 1 1 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 ETO13287.1 - 0.036 13.7 4.9 0.32 10.7 1.3 2.6 2 0 0 2 2 2 0 PHD-finger zf-CHCC PF10276.4 ETO13287.1 - 0.068 13.0 1.0 0.2 11.4 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger domain ADK_lid PF05191.9 ETO13287.1 - 0.086 12.5 0.7 0.086 12.5 0.5 2.1 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-BED PF02892.10 ETO13287.1 - 0.13 12.0 17.2 0.22 11.3 3.2 3.2 2 1 1 3 3 2 0 BED zinc finger DZR PF12773.2 ETO13287.1 - 0.14 11.9 6.9 1.7 8.5 2.3 3.2 2 1 0 2 2 2 0 Double zinc ribbon zf-C2HC_2 PF13913.1 ETO13287.1 - 0.35 10.5 7.5 7.1 6.4 0.2 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-ISL3 PF14690.1 ETO13287.1 - 0.52 10.3 5.8 15 5.6 0.0 3.4 3 1 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn-ribbon_8 PF09723.5 ETO13287.1 - 0.88 9.5 4.3 4 7.4 0.8 2.8 1 1 1 2 2 2 0 Zinc ribbon domain FYVE PF01363.16 ETO13287.1 - 3.2 7.7 10.5 11 6.0 7.3 2.0 1 1 0 1 1 1 0 FYVE zinc finger zf-CHY PF05495.7 ETO13287.1 - 4.3 7.5 12.0 1.9 8.7 2.3 2.9 1 1 1 2 2 2 0 CHY zinc finger Rad50_zn_hook PF04423.9 ETO13287.1 - 4.4 6.8 8.1 6.7 6.2 0.2 3.5 1 1 2 3 3 3 0 Rad50 zinc hook motif FYVE_2 PF02318.11 ETO13287.1 - 8.3 6.3 8.8 2.9 7.8 3.1 2.1 1 1 1 2 2 2 0 FYVE-type zinc finger His_Phos_1 PF00300.17 ETO13288.1 - 8.6e-13 48.6 0.0 1.4e-12 48.0 0.0 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF2969 PF11184.3 ETO13288.1 - 0.053 13.6 3.2 1.1 9.4 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2969) Frag1 PF10277.4 ETO13289.1 - 0.077 12.4 0.2 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family zf-Di19 PF05605.7 ETO13290.1 - 5.7e-07 29.5 1.6 5.7e-07 29.5 1.1 2.8 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 ETO13290.1 - 0.2 12.0 13.3 2 8.8 0.0 4.6 5 0 0 5 5 5 0 Zinc-finger double domain DUF3505 PF12013.3 ETO13290.1 - 0.24 11.6 11.1 0.99 9.6 1.4 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3505) zf-BED PF02892.10 ETO13290.1 - 0.31 10.8 10.1 2.4 7.9 0.1 3.1 2 1 1 3 3 3 0 BED zinc finger zf-C2H2_4 PF13894.1 ETO13290.1 - 0.42 11.0 0.2 0.42 11.0 0.1 4.7 4 1 0 4 4 4 0 C2H2-type zinc finger DUF1178 PF06676.6 ETO13290.1 - 0.44 10.7 5.3 1.1 9.4 3.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1178) zf-met2 PF12907.2 ETO13290.1 - 0.47 10.4 17.8 4.5 7.3 0.2 4.2 2 2 1 3 3 3 0 Zinc-binding Sgf11 PF08209.6 ETO13290.1 - 1.9 7.8 6.3 2.3 7.5 0.0 3.3 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zf-met PF12874.2 ETO13290.1 - 2.9 8.2 16.6 11 6.4 0.5 4.6 3 1 0 3 3 3 0 Zinc-finger of C2H2 type CH PF00307.26 ETO13291.1 - 3.9e-07 30.0 2.6 6.6e-07 29.3 0.1 2.3 2 1 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 ETO13291.1 - 4e-05 23.1 0.0 0.00014 21.4 0.0 1.9 1 0 0 1 1 1 1 CAMSAP CH domain TMF_TATA_bd PF12325.3 ETO13291.1 - 0.023 14.4 0.8 0.057 13.1 0.6 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding EB1 PF03271.12 ETO13291.1 - 0.28 11.2 2.6 0.5 10.4 0.5 2.4 2 0 0 2 2 2 0 EB1-like C-terminal motif DUF1980 PF09323.5 ETO13292.1 - 0.033 13.9 0.2 0.044 13.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) RuvB_C PF05491.8 ETO13292.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB C-terminus GvpK PF05121.7 ETO13293.1 - 0.089 12.6 2.9 0.41 10.4 0.3 2.7 3 0 0 3 3 3 0 Gas vesicle protein K POX PF07526.6 ETO13293.1 - 0.41 10.8 12.5 0.49 10.6 0.1 2.5 3 0 0 3 3 3 0 Associated with HOX ADK PF00406.17 ETO13294.1 - 8.5e-37 126.3 0.0 1.9e-36 125.2 0.0 1.6 2 0 0 2 2 2 1 Adenylate kinase ADK_lid PF05191.9 ETO13294.1 - 1e-07 31.4 2.9 2.8e-07 30.0 2.0 1.8 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 ETO13294.1 - 1.1e-06 29.5 0.0 3.5e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 ETO13294.1 - 7e-05 22.7 0.0 0.00017 21.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETO13294.1 - 0.00065 19.9 0.0 0.0018 18.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 ETO13294.1 - 0.022 13.7 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus HypA PF01155.14 ETO13294.1 - 0.033 13.8 0.0 0.065 12.9 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Zeta_toxin PF06414.7 ETO13294.1 - 0.05 12.6 0.0 0.092 11.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AgrB PF04647.10 ETO13294.1 - 0.66 9.0 10.0 0.066 12.2 3.5 1.8 2 0 0 2 2 2 0 Accessory gene regulator B Kelch_1 PF01344.20 ETO13295.1 - 3.5e-07 29.6 0.8 3.5e-06 26.4 0.2 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETO13295.1 - 1.1e-05 25.3 0.7 9.9e-05 22.3 0.0 2.7 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETO13295.1 - 0.00024 20.7 2.6 0.055 13.2 0.0 3.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO13295.1 - 0.0036 17.4 0.0 0.1 12.8 0.0 2.8 2 1 1 3 3 3 1 Galactose oxidase, central domain Rieske_2 PF13806.1 ETO13295.1 - 0.024 14.3 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain Kelch_5 PF13854.1 ETO13295.1 - 0.029 14.3 0.1 0.11 12.4 0.1 2.1 1 0 0 1 1 1 0 Kelch motif Sulfate_transp PF00916.15 ETO13296.1 - 1.9e-19 69.7 4.1 4.7e-19 68.4 2.9 1.6 1 0 0 1 1 1 1 Sulfate transporter family STAS PF01740.16 ETO13296.1 - 0.00083 18.7 0.0 0.0024 17.2 0.0 1.7 2 0 0 2 2 2 1 STAS domain MnhB PF04039.8 ETO13296.1 - 0.028 14.4 6.8 0.065 13.3 4.7 1.6 1 0 0 1 1 1 0 Domain related to MnhB subunit of Na+/H+ antiporter CRAL_TRIO_2 PF13716.1 ETO13296.1 - 0.035 14.0 0.1 0.16 11.8 0.0 2.0 1 1 1 2 2 2 0 Divergent CRAL/TRIO domain DUF4118 PF13493.1 ETO13296.1 - 0.48 10.6 13.3 0.58 10.3 1.9 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4118) Sialidase_penC PF12135.3 ETO13297.1 - 0.088 12.4 1.5 0.23 11.1 0.7 2.0 2 0 0 2 2 2 0 Sialidase enzyme penultimate C terminal domain Serpin PF00079.15 ETO13298.1 - 0.00021 20.5 0.1 0.00025 20.3 0.0 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Pex24p PF06398.6 ETO13299.1 - 5.4 5.6 7.3 8 5.1 5.0 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin HORMA PF02301.13 ETO13301.1 - 7e-09 35.4 0.3 7e-09 35.4 0.2 1.0 1 0 0 1 1 1 1 HORMA domain HTH_45 PF14947.1 ETO13302.1 - 0.0034 17.1 0.0 0.0073 16.1 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix FeoC PF09012.5 ETO13302.1 - 0.0099 15.5 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 FeoC like transcriptional regulator HTH_24 PF13412.1 ETO13302.1 - 0.011 15.1 0.0 0.025 13.9 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_27 PF13463.1 ETO13302.1 - 0.011 16.0 0.0 8 6.8 0.0 2.5 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_5 PF01022.15 ETO13302.1 - 0.025 14.2 0.0 0.059 13.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family RPA_C PF08784.6 ETO13302.1 - 0.056 13.8 0.8 0.34 11.3 0.0 2.2 2 0 0 2 2 2 0 Replication protein A C terminal IL3 PF02059.10 ETO13302.1 - 0.069 13.1 0.4 0.15 12.0 0.1 1.7 1 1 0 1 1 1 0 Interleukin-3 DDRGK PF09756.4 ETO13302.1 - 0.57 9.5 9.8 2 7.7 6.1 1.9 1 1 0 1 1 1 0 DDRGK domain Dus PF01207.12 ETO13303.1 - 9.5e-38 129.7 0.1 1.1e-37 129.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) ACT PF01842.20 ETO13303.1 - 0.013 15.0 0.0 3.4 7.2 0.0 2.6 2 0 0 2 2 2 0 ACT domain DHO_dh PF01180.16 ETO13303.1 - 0.015 14.2 0.0 0.017 14.1 0.0 1.1 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase PdxJ PF03740.8 ETO13303.1 - 0.018 14.2 0.1 0.043 12.9 0.1 1.6 1 1 1 2 2 2 0 Pyridoxal phosphate biosynthesis protein PdxJ DUF3839 PF12943.2 ETO13303.1 - 0.061 12.4 0.1 0.065 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3839) SOR_SNZ PF01680.12 ETO13303.1 - 0.093 12.3 0.1 0.25 10.9 0.1 1.9 1 1 0 1 1 1 0 SOR/SNZ family Pterin_bind PF00809.17 ETO13303.1 - 0.12 11.7 0.0 0.33 10.2 0.0 1.7 2 0 0 2 2 2 0 Pterin binding enzyme Glutaredoxin PF00462.19 ETO13304.1 - 0.028 14.4 0.0 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 Glutaredoxin NAD_binding_6 PF08030.7 ETO13304.1 - 0.59 10.0 5.8 3.6 7.4 1.9 2.2 1 1 1 2 2 2 0 Ferric reductase NAD binding domain CorA PF01544.13 ETO13305.1 - 3.9e-38 131.1 0.2 6.9e-38 130.3 0.2 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Zip PF02535.17 ETO13306.1 - 1.2 8.0 3.9 1.4 7.8 2.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Paf1 PF03985.8 ETO13307.1 - 0.69 8.5 19.4 0.85 8.2 13.4 1.1 1 0 0 1 1 1 0 Paf1 FCP1_C PF09309.5 ETO13307.1 - 1.1 8.5 16.5 1.5 8.0 11.1 1.5 1 1 0 1 1 1 0 FCP1, C-terminal Menin PF05053.8 ETO13307.1 - 2.1 6.4 9.4 2.2 6.3 6.5 1.1 1 0 0 1 1 1 0 Menin CDC45 PF02724.9 ETO13307.1 - 2.3 6.1 13.3 2.6 5.9 9.2 1.0 1 0 0 1 1 1 0 CDC45-like protein CDK5_activator PF03261.10 ETO13307.1 - 6 6.0 15.0 7.2 5.8 10.4 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Borrelia_P83 PF05262.6 ETO13307.1 - 6.6 4.8 14.9 6.3 4.9 10.3 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Mem_trans PF03547.13 ETO13307.1 - 7.2 4.7 6.5 7.7 4.7 4.5 1.1 1 0 0 1 1 1 0 Membrane transport protein Glyco_hydro_18 PF00704.23 ETO13308.1 - 1.9e-10 40.7 1.1 2.2e-10 40.5 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 7tm_7 PF08395.7 ETO13309.1 - 0.0031 16.6 0.1 0.0037 16.3 0.1 1.1 1 0 0 1 1 1 1 7tm Chemosensory receptor SLAC1 PF03595.12 ETO13309.1 - 0.0085 14.7 0.6 0.011 14.3 0.4 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF2207 PF09972.4 ETO13309.1 - 0.038 12.5 0.0 0.044 12.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Sigma70_ner PF04546.8 ETO13309.1 - 0.074 12.6 1.6 0.094 12.3 1.1 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region CobT PF06213.7 ETO13309.1 - 0.12 11.4 9.3 0.16 11.0 6.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Vfa1 PF08432.5 ETO13309.1 - 0.36 10.8 4.8 0.49 10.3 3.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PBP1_TM PF14812.1 ETO13309.1 - 0.69 10.2 7.7 1.3 9.3 5.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RRN3 PF05327.6 ETO13309.1 - 0.9 7.5 5.0 1.2 7.1 3.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2457 PF10446.4 ETO13309.1 - 4.4 5.9 11.7 5.6 5.5 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Exo_endo_phos PF03372.18 ETO13310.1 - 2.1e-15 57.3 1.0 2.6e-15 57.0 0.7 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4366 PF14283.1 ETO13311.1 - 0.035 13.5 0.7 0.048 13.0 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) PA26 PF04636.8 ETO13311.1 - 0.36 9.4 7.1 0.44 9.1 4.9 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Nucleocapsid-N PF11030.3 ETO13311.1 - 4.9 6.9 10.4 8.2 6.2 7.2 1.3 1 0 0 1 1 1 0 Nucleocapsid protein N API5 PF05918.6 ETO13312.1 - 0.018 13.5 4.3 0.024 13.1 3.0 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF1510 PF07423.6 ETO13312.1 - 0.06 12.7 10.7 0.087 12.1 7.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 ETO13312.1 - 0.063 11.3 8.5 0.084 10.8 5.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.5 ETO13312.1 - 0.2 11.6 11.7 0.4 10.6 8.1 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CobT PF06213.7 ETO13312.1 - 0.36 9.9 9.7 0.52 9.4 6.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT UN_NPL4 PF11543.3 ETO13313.1 - 0.00056 20.1 0.1 0.049 13.9 0.1 3.4 3 0 0 3 3 3 1 Nuclear pore localisation protein NPL4 ubiquitin PF00240.18 ETO13313.1 - 0.032 13.6 3.5 0.15 11.4 0.2 3.5 3 1 0 3 3 3 0 Ubiquitin family PB1 PF00564.19 ETO13313.1 - 0.06 13.0 0.6 9.2 6.0 0.0 3.1 3 0 0 3 3 3 0 PB1 domain Myc-LZ PF02344.10 ETO13313.1 - 0.13 11.9 6.7 0.36 10.4 4.6 1.8 1 0 0 1 1 1 0 Myc leucine zipper domain VanY PF02557.12 ETO13315.1 - 0.05 13.4 0.2 0.083 12.7 0.1 1.4 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Ras PF00071.17 ETO13316.1 - 1.6e-18 66.5 0.1 1.3e-15 57.1 0.0 2.4 2 1 0 2 2 2 2 Ras family Miro PF08477.8 ETO13316.1 - 4.2e-12 46.6 0.0 7.7e-10 39.2 0.0 2.9 3 0 0 3 3 3 1 Miro-like protein GTP_EFTU PF00009.22 ETO13316.1 - 4.5e-07 29.4 0.2 0.0028 17.0 0.0 2.9 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Arf PF00025.16 ETO13316.1 - 2.7e-06 26.7 0.3 0.016 14.4 0.0 2.8 1 1 2 3 3 3 2 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETO13316.1 - 7.8e-05 22.6 0.0 0.00035 20.5 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 ETO13316.1 - 0.00013 21.2 0.1 0.00084 18.5 0.1 2.1 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_18 PF13238.1 ETO13316.1 - 0.0028 17.9 0.6 0.028 14.7 0.4 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETO13316.1 - 0.01 15.8 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 ETO13316.1 - 0.014 15.5 0.0 0.12 12.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 ETO13316.1 - 0.019 14.5 0.0 0.057 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 ETO13316.1 - 0.02 14.6 0.1 0.042 13.5 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.13 ETO13316.1 - 0.063 12.8 0.1 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA PF00004.24 ETO13316.1 - 0.064 13.4 0.0 0.2 11.8 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 ETO13316.1 - 0.075 13.8 0.9 0.12 13.2 0.2 1.8 2 1 0 2 2 2 0 AAA domain NACHT PF05729.7 ETO13316.1 - 0.14 11.8 0.0 0.34 10.5 0.0 1.8 1 1 0 1 1 1 0 NACHT domain XAP5 PF04921.9 ETO13317.1 - 3.8 7.0 12.6 0.73 9.3 1.5 2.4 2 1 0 2 2 2 0 XAP5, circadian clock regulator Methyltransf_4 PF02390.12 ETO13318.1 - 2.8e-35 121.1 2.3 1.6e-34 118.6 1.6 1.9 1 1 0 1 1 1 1 Putative methyltransferase DUF3940 PF13076.1 ETO13318.1 - 0.075 12.5 0.1 0.45 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3940) FliJ PF02050.11 ETO13319.1 - 0.01 15.9 8.9 0.01 15.9 6.2 2.6 2 1 1 3 3 3 1 Flagellar FliJ protein Sec20 PF03908.8 ETO13319.1 - 0.047 13.3 1.9 0.096 12.4 0.8 1.9 1 1 0 1 1 1 0 Sec20 GET2 PF08690.5 ETO13319.1 - 0.061 12.5 4.5 0.074 12.2 3.1 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 KIP1 PF07765.7 ETO13319.1 - 0.26 11.1 1.5 0.43 10.4 0.9 1.5 1 1 0 1 1 1 0 KIP1-like protein Tox-PL-2 PF15643.1 ETO13319.1 - 0.3 11.0 4.1 0.19 11.7 0.4 2.2 2 1 1 3 3 3 0 Papain fold toxin 2 ACCA PF03255.9 ETO13319.1 - 1.4 8.4 6.5 0.66 9.5 2.9 1.7 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF913 PF06025.7 ETO13319.1 - 1.6 7.4 5.8 1.9 7.1 4.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Ndufs5 PF10200.4 ETO13319.1 - 1.7 8.6 6.2 0.81 9.7 2.3 2.0 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa FHIPEP PF00771.15 ETO13319.1 - 1.7 6.8 7.1 2 6.6 4.9 1.1 1 0 0 1 1 1 0 FHIPEP family NPIP PF06409.6 ETO13319.1 - 2.4 6.8 7.2 3 6.4 5.0 1.3 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) Seryl_tRNA_N PF02403.17 ETO13319.1 - 3.7 7.5 19.3 5.4 7.0 7.8 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ScpA_ScpB PF02616.9 ETO13319.1 - 6.9 6.1 16.2 3 7.3 9.0 1.7 1 1 1 2 2 2 0 ScpA/B protein Ank_4 PF13637.1 ETO13320.1 - 0.0083 16.6 0.0 7.6 7.1 0.0 3.7 3 1 0 3 3 3 1 Ankyrin repeats (many copies) DEAD_assoc PF08494.6 ETO13320.1 - 0.058 13.1 0.0 0.59 9.8 0.0 2.1 2 0 0 2 2 2 0 DEAD/H associated DUF1673 PF07895.6 ETO13320.1 - 0.83 9.1 8.3 1.1 8.7 0.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1673) XisI PF08869.6 ETO13321.1 - 0.04 14.0 0.4 0.061 13.4 0.3 1.3 1 0 0 1 1 1 0 XisI protein Cys_rich_KTR PF14205.1 ETO13321.1 - 0.051 13.0 0.0 0.15 11.4 0.0 1.8 1 0 0 1 1 1 0 Cysteine-rich KTR EF-hand_1 PF00036.27 ETO13322.1 - 4e-28 94.5 21.7 8.8e-09 34.0 0.5 4.6 4 1 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 ETO13322.1 - 3.4e-26 91.1 15.7 1.6e-13 50.5 2.0 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO13322.1 - 9e-23 78.0 19.0 2.9e-08 32.9 0.6 5.1 3 1 3 6 6 6 4 EF-hand domain EF-hand_8 PF13833.1 ETO13322.1 - 1.1e-19 69.8 21.7 1.2e-12 47.2 1.3 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 ETO13322.1 - 1.2e-17 62.3 21.4 7.4e-09 34.5 1.2 5.3 4 1 1 5 5 5 4 EF hand EF-hand_9 PF14658.1 ETO13322.1 - 1.1e-11 44.4 1.9 5.8e-05 22.9 0.0 2.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_4 PF12763.2 ETO13322.1 - 1.6e-07 30.9 9.6 0.00018 21.1 0.7 3.5 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand TerB PF05099.8 ETO13322.1 - 1.3e-06 28.2 1.5 0.018 14.7 0.0 3.1 2 1 1 3 3 3 2 Tellurite resistance protein TerB SPARC_Ca_bdg PF10591.4 ETO13322.1 - 2.2e-06 27.6 4.0 0.015 15.3 0.0 2.5 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.8 ETO13322.1 - 0.0008 19.0 0.2 0.49 9.9 0.0 2.3 2 0 0 2 2 2 2 Caleosin related protein EF-hand_10 PF14788.1 ETO13322.1 - 0.0011 18.5 2.6 0.04 13.5 0.1 2.7 2 0 0 2 2 2 1 EF hand SpoVIF PF14069.1 ETO13322.1 - 0.0084 15.8 0.2 0.17 11.6 0.0 2.6 2 1 0 2 2 2 1 Stage VI sporulation protein F LNS2 PF08235.8 ETO13322.1 - 0.025 14.1 0.8 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) DUF1456 PF07308.8 ETO13322.1 - 0.032 14.2 1.6 1.5 8.9 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) RNA_pol_Rpb1_5 PF04998.12 ETO13322.1 - 0.055 12.7 2.3 0.072 12.3 1.6 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 FRG1 PF06229.7 ETO13322.1 - 0.61 9.5 5.8 0.47 9.8 2.9 1.6 2 0 0 2 2 2 0 FRG1-like family IQ-like PF15157.1 ETO13322.1 - 2.4 8.4 5.2 0.97 9.6 0.3 2.6 2 2 0 2 2 2 0 IQ-like Drc1-Sld2 PF11719.3 ETO13323.1 - 1.1 8.2 16.3 1.3 8.0 11.3 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein DUF1510 PF07423.6 ETO13323.1 - 2.5 7.4 22.0 2.8 7.2 15.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) G-alpha PF00503.15 ETO13324.1 - 7.6e-15 54.4 1.1 1.1e-14 53.9 0.7 1.2 1 0 0 1 1 1 1 G-protein alpha subunit DUF603 PF04645.7 ETO13325.1 - 0.068 13.1 1.0 0.15 11.9 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF603 DUF211 PF02680.9 ETO13325.1 - 0.18 11.6 6.9 0.35 10.6 4.8 1.5 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 DASH_Dad4 PF08650.5 ETO13325.1 - 0.44 10.5 6.6 0.84 9.5 1.1 2.5 1 1 1 2 2 2 0 DASH complex subunit Dad4 Anth_Ig PF05587.8 ETO13326.1 - 0.0046 16.7 3.8 0.15 11.8 0.0 3.0 3 0 0 3 3 3 2 Anthrax receptor extracellular domain RCC1 PF00415.13 ETO13327.1 - 0.0084 16.2 0.0 0.026 14.7 0.0 1.8 1 0 0 1 1 1 1 Regulator of chromosome condensation (RCC1) repeat AAA_11 PF13086.1 ETO13327.1 - 0.04 13.4 0.4 0.052 13.1 0.3 1.2 1 0 0 1 1 1 0 AAA domain TIG PF01833.19 ETO13327.1 - 0.16 11.9 2.0 1.1 9.3 1.0 2.6 1 1 1 2 2 2 0 IPT/TIG domain S_layer_C PF05124.7 ETO13327.1 - 0.16 11.5 5.0 0.27 10.8 3.5 1.2 1 0 0 1 1 1 0 S-layer like family, C-terminal region SET PF00856.23 ETO13328.1 - 0.11 12.8 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 SET domain RuvB_C PF05491.8 ETO13329.1 - 0.091 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB C-terminus WD40 PF00400.27 ETO13330.1 - 3.3e-14 52.1 1.4 0.0034 17.2 0.0 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat Nucleopor_Nup85 PF07575.8 ETO13332.1 - 3e-06 25.7 0.7 4.1e-06 25.2 0.5 1.1 1 0 0 1 1 1 1 Nup85 Nucleoporin E1-E2_ATPase PF00122.15 ETO13333.1 - 1e-06 27.9 0.0 1.3e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 ETO13333.1 - 0.0014 18.7 0.0 0.0026 17.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase OEP PF02321.13 ETO13333.1 - 0.022 14.3 0.2 0.038 13.5 0.1 1.3 1 0 0 1 1 1 0 Outer membrane efflux protein Mlo PF03094.10 ETO13334.1 - 0.045 11.8 0.0 0.062 11.4 0.0 1.2 1 0 0 1 1 1 0 Mlo family HEAT_EZ PF13513.1 ETO13334.1 - 0.14 12.6 4.2 0.11 12.9 0.9 2.3 2 1 1 3 3 3 0 HEAT-like repeat DUF3730 PF12530.3 ETO13335.1 - 5.1e-05 23.3 0.3 7.6e-05 22.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3730) MMS19_C PF12460.3 ETO13335.1 - 5.3e-05 22.1 0.0 0.00098 17.9 0.0 2.1 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal HEAT PF02985.17 ETO13335.1 - 6.3e-05 22.7 1.5 0.095 12.8 0.0 3.7 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 ETO13335.1 - 0.006 16.8 0.0 1.3 9.3 0.0 2.4 2 1 1 3 3 3 2 HEAT repeats Vac14_Fab1_bd PF12755.2 ETO13335.1 - 0.0061 16.9 2.7 0.009 16.3 0.1 2.5 2 1 0 3 3 3 1 Vacuolar 14 Fab1-binding region TIP120 PF08623.5 ETO13335.1 - 0.01 15.4 0.5 1.4 8.4 0.3 2.2 1 1 1 2 2 2 0 TATA-binding protein interacting (TIP20) Cnd1 PF12717.2 ETO13335.1 - 0.014 15.2 0.4 0.067 13.0 0.1 2.1 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 MMS19_N PF14500.1 ETO13335.1 - 0.023 13.9 0.4 0.13 11.5 0.1 1.9 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II DUF2435 PF10363.4 ETO13335.1 - 0.055 13.3 0.0 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) ATP-synt_8 PF00895.15 ETO13336.1 - 0.12 12.6 1.3 0.3 11.3 0.9 1.7 1 0 0 1 1 1 0 ATP synthase protein 8 HEAT_2 PF13646.1 ETO13336.1 - 0.16 12.2 0.1 0.67 10.2 0.0 2.0 1 1 1 2 2 2 0 HEAT repeats RGS PF00615.14 ETO13337.1 - 0.0017 18.4 2.7 0.0027 17.7 1.8 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain TPR_11 PF13414.1 ETO13339.1 - 2.6e-18 65.4 14.9 2.8e-06 26.8 0.1 6.7 4 1 0 6 6 6 4 TPR repeat TPR_12 PF13424.1 ETO13339.1 - 9.2e-14 51.1 16.0 5.8e-05 22.9 0.0 6.2 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO13339.1 - 5.1e-10 38.7 5.7 0.86 9.9 0.0 8.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO13339.1 - 8.4e-09 35.8 0.5 0.45 11.2 0.0 4.9 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO13339.1 - 4e-08 32.5 30.4 0.04 13.5 0.3 8.7 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO13339.1 - 3.5e-07 29.6 30.5 0.61 10.1 0.1 9.4 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO13339.1 - 3.4e-06 27.2 1.7 0.22 11.8 0.0 5.0 4 2 0 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO13339.1 - 2.8e-05 24.3 1.8 0.71 10.6 0.0 6.2 5 3 2 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO13339.1 - 5.4e-05 22.6 23.6 0.25 11.2 0.1 8.3 9 0 0 9 9 9 2 Tetratricopeptide repeat CENP-B_dimeris PF09026.5 ETO13339.1 - 0.00044 20.4 1.2 0.00044 20.4 0.9 7.2 5 1 2 7 7 4 1 Centromere protein B dimerisation domain TPR_6 PF13174.1 ETO13339.1 - 0.0065 16.8 3.4 6.1 7.5 0.0 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_3 PF07720.7 ETO13339.1 - 0.021 14.6 12.3 0.076 12.8 0.9 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 ETO13339.1 - 0.031 14.1 0.3 12 5.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 ETO13339.1 - 3 7.8 9.2 21 5.2 0.0 4.7 6 0 0 6 6 5 0 Tetratricopeptide repeat FYVE PF01363.16 ETO13341.1 - 2e-06 27.5 1.4 2e-06 27.5 1.0 2.7 3 1 0 3 3 3 1 FYVE zinc finger PH_11 PF15413.1 ETO13341.1 - 0.041 14.1 0.3 0.53 10.5 0.0 3.0 3 0 0 3 3 3 0 Pleckstrin homology domain D-ser_dehydrat PF14031.1 ETO13341.1 - 0.054 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative serine dehydratase domain Ndc1_Nup PF09531.5 ETO13342.1 - 0.072 11.4 5.0 0.11 10.8 3.5 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Zip PF02535.17 ETO13342.1 - 2.6 6.9 8.1 9 5.1 0.1 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter EphA2_TM PF14575.1 ETO13343.1 - 0.15 12.5 1.4 0.19 12.1 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF1049 PF06305.6 ETO13343.1 - 0.37 10.2 2.3 0.41 10.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF843 PF05814.6 ETO13343.1 - 2.2 8.1 4.7 0.92 9.3 0.7 2.1 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) RGS PF00615.14 ETO13344.1 - 9.1e-06 25.7 1.5 9.1e-06 25.7 1.0 2.5 2 1 0 2 2 2 1 Regulator of G protein signaling domain Daxx PF03344.10 ETO13344.1 - 0.71 8.2 35.1 0.093 11.1 10.4 2.2 2 0 0 2 2 2 0 Daxx Family Spore_coat_CotO PF14153.1 ETO13344.1 - 0.75 9.2 21.0 1 8.7 5.3 2.5 2 0 0 2 2 2 0 Spore coat protein CotO TFIIF_alpha PF05793.7 ETO13344.1 - 2.7 6.2 39.2 0.39 9.0 11.6 2.2 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FAR1 PF03101.10 ETO13345.1 - 0.0024 18.3 0.6 0.0027 18.1 0.4 1.2 1 0 0 1 1 1 1 FAR1 DNA-binding domain Membrane_bind PF14564.1 ETO13345.1 - 0.059 13.5 0.9 0.09 12.9 0.5 1.5 1 1 0 1 1 1 0 Membrane binding Sof1 PF04158.9 ETO13345.1 - 0.19 11.8 3.5 0.27 11.3 2.4 1.3 1 0 0 1 1 1 0 Sof1-like domain RRM_1 PF00076.17 ETO13347.1 - 7.6e-09 35.0 0.0 1.5e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO13347.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CIAPIN1 PF05093.8 ETO13347.1 - 0.34 11.0 3.5 0.48 10.5 2.1 1.4 1 1 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis NUP50 PF08911.6 ETO13350.1 - 0.023 15.0 1.2 0.034 14.5 0.0 1.9 2 0 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) DUF605 PF04652.11 ETO13350.1 - 5 6.4 28.3 6.2 6.1 19.6 1.1 1 0 0 1 1 1 0 Vta1 like Vfa1 PF08432.5 ETO13350.1 - 8.3 6.3 15.6 0.053 13.5 1.7 2.5 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 Ribosomal_60s PF00428.14 ETO13352.1 - 0.0032 17.8 5.7 0.0032 17.8 4.0 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein EBV-NA3 PF05009.7 ETO13352.1 - 0.014 14.6 0.2 0.028 13.6 0.1 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) ABC2_membrane_5 PF13346.1 ETO13352.1 - 0.027 13.7 1.2 0.036 13.3 0.8 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Tom37_C PF11801.3 ETO13352.1 - 4.6 7.0 6.2 1 9.2 0.8 2.2 2 0 0 2 2 2 0 Tom37 C-terminal domain Myb_CC_LHEQLE PF14379.1 ETO13353.1 - 0.052 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif SGL PF08450.7 ETO13354.1 - 5e-07 29.3 1.0 0.003 16.9 0.0 3.5 1 1 1 3 3 3 3 SMP-30/Gluconolaconase/LRE-like region UPF0203 PF05254.7 ETO13355.1 - 8.5e-05 22.3 9.9 8.5e-05 22.3 6.9 2.1 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0203) DUF3128 PF11326.3 ETO13355.1 - 0.14 12.3 5.2 0.21 11.6 2.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Cmc1 PF08583.5 ETO13355.1 - 0.53 10.0 7.3 30 4.4 5.0 2.6 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.11 ETO13355.1 - 0.65 9.9 4.5 2.3 8.2 3.1 1.9 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein DUF1212 PF06738.7 ETO13356.1 - 0.018 14.5 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) DNA_pol3_a_NI PF14480.1 ETO13356.1 - 0.62 9.7 3.2 2.6 7.7 0.4 2.5 2 1 0 2 2 2 0 DNA polymerase III polC-type N-terminus I DUF4184 PF13803.1 ETO13357.1 - 0.0086 15.4 0.2 0.0086 15.4 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4184) DUF2615 PF11027.3 ETO13357.1 - 0.022 14.6 0.3 5 7.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) ECF-ribofla_trS PF07155.7 ETO13357.1 - 0.34 10.6 3.0 12 5.5 0.0 2.3 2 0 0 2 2 2 0 ECF-type riboflavin transporter, S component DUF506 PF04720.7 ETO13358.1 - 0.11 12.1 1.0 0.18 11.4 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Mucin PF01456.12 ETO13358.1 - 0.11 12.2 22.0 0.033 13.9 13.1 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein SSP160 PF06933.6 ETO13358.1 - 7.1 4.4 16.7 12 3.7 11.6 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 BSP_II PF05432.6 ETO13358.1 - 9.4 5.4 9.2 16 4.6 6.4 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Alba PF01918.16 ETO13359.1 - 0.0014 18.1 0.3 0.0034 16.9 0.2 1.6 1 0 0 1 1 1 1 Alba Actin PF00022.14 ETO13360.1 - 6.4e-19 67.6 0.0 7.9e-19 67.3 0.0 1.0 1 0 0 1 1 1 1 Actin Actin PF00022.14 ETO13361.1 - 1.5e-74 250.8 0.0 5.1e-74 249.0 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 ETO13361.1 - 0.0038 15.8 0.0 0.0076 14.8 0.0 1.4 1 1 0 1 1 1 1 MreB/Mbl protein Arm PF00514.18 ETO13363.1 - 1.7e-10 40.2 0.2 3.9e-05 23.2 0.0 2.9 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Dynamitin PF04912.9 ETO13363.1 - 4.5e-09 35.5 1.7 7.8e-09 34.8 1.2 1.3 1 0 0 1 1 1 1 Dynamitin eIF-4B PF06273.6 ETO13363.1 - 0.0018 17.1 0.4 0.0027 16.5 0.2 1.2 1 0 0 1 1 1 1 Plant specific eukaryotic initiation factor 4B HEAT_2 PF13646.1 ETO13363.1 - 0.033 14.4 0.0 0.064 13.5 0.0 1.5 1 0 0 1 1 1 0 HEAT repeats Mo-nitro_C PF06967.6 ETO13364.1 - 0.0061 16.6 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 Mo-dependent nitrogenase C-terminus PPR_2 PF13041.1 ETO13364.1 - 0.077 12.9 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 PPR repeat family Glyco_transf_49 PF13896.1 ETO13365.1 - 0.016 14.3 0.2 0.016 14.3 0.1 1.7 2 1 0 2 2 2 0 Glycosyl-transferase for dystroglycan Vezatin PF12632.2 ETO13366.1 - 0.053 12.6 0.3 0.053 12.6 0.2 1.6 1 1 0 2 2 2 0 Mysoin-binding motif of peroxisomes CDC45 PF02724.9 ETO13366.1 - 0.08 10.9 11.0 0.085 10.8 7.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Myc_N PF01056.13 ETO13366.1 - 0.085 12.0 3.6 0.076 12.1 2.5 1.1 1 0 0 1 1 1 0 Myc amino-terminal region TRAP_alpha PF03896.11 ETO13366.1 - 0.18 10.7 2.0 0.16 10.9 1.4 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sporozoite_P67 PF05642.6 ETO13366.1 - 0.21 9.4 4.8 0.2 9.4 3.3 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pox_RNA_Pol_19 PF05320.7 ETO13366.1 - 0.8 9.4 5.9 1 9.1 4.1 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Gti1_Pac2 PF09729.4 ETO13366.1 - 0.88 9.4 4.6 1.1 9.1 3.2 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Nop14 PF04147.7 ETO13366.1 - 0.96 7.2 11.6 1.2 6.9 8.1 1.1 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 ETO13366.1 - 3.6 7.1 8.0 4.5 6.8 5.5 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CobT PF06213.7 ETO13366.1 - 5.3 6.0 12.6 6.3 5.8 8.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT YL1 PF05764.8 ETO13366.1 - 6.6 6.2 15.7 8.1 5.9 10.9 1.3 1 1 0 1 1 1 0 YL1 nuclear protein DDE_Tnp_1 PF01609.16 ETO13367.1 - 0.034 13.6 0.2 0.047 13.2 0.2 1.2 1 0 0 1 1 1 0 Transposase DDE domain zf-H2C2_5 PF13909.1 ETO13367.1 - 4.8 7.6 7.8 8.6 6.8 1.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Nop14 PF04147.7 ETO13368.1 - 0.0029 15.6 7.4 0.0036 15.3 5.2 1.2 1 0 0 1 1 1 1 Nop14-like family Sigma70_ner PF04546.8 ETO13368.1 - 0.0057 16.3 2.5 0.0089 15.6 1.7 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region Daxx PF03344.10 ETO13368.1 - 0.03 12.8 9.8 0.036 12.5 6.8 1.1 1 0 0 1 1 1 0 Daxx Family FLYWCH PF04500.11 ETO13368.1 - 0.04 13.8 8.3 0.044 13.6 0.4 2.7 3 0 0 3 3 3 0 FLYWCH zinc finger domain DUF2457 PF10446.4 ETO13368.1 - 0.69 8.5 21.4 0.061 12.0 11.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.5 ETO13368.1 - 2.2 8.6 14.6 5.1 7.4 10.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 ETO13368.1 - 5.5 6.5 13.3 13 5.2 9.2 1.5 1 0 0 1 1 1 0 Nucleoplasmin CobT PF06213.7 ETO13368.1 - 9.6 5.2 13.4 16 4.5 9.3 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Peptidase_M13_N PF05649.8 ETO13369.1 - 5.6e-07 28.9 1.1 1.1e-06 28.0 0.8 1.4 1 1 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 ETO13370.1 - 1.9e-37 128.4 0.8 1.2e-36 125.8 0.6 2.1 1 1 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.8 ETO13370.1 - 9.3e-10 38.0 0.0 1.4e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Ribosomal_60s PF00428.14 ETO13371.1 - 0.082 13.3 4.6 0.58 10.5 3.2 2.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Phage_tail_U PF06141.6 ETO13371.1 - 0.16 11.9 0.0 0.16 11.9 0.0 2.8 3 1 0 3 3 3 0 Phage minor tail protein U ERCC4 PF02732.10 ETO13372.1 - 2.5e-26 92.1 0.6 4e-26 91.4 0.4 1.3 1 0 0 1 1 1 1 ERCC4 domain CAF1C_H4-bd PF12265.3 ETO13372.1 - 0.082 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex zf-C2H2 PF00096.21 ETO13373.1 - 0.026 14.8 3.0 0.026 14.8 2.1 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETO13373.1 - 1.7 9.1 10.4 0.33 11.3 2.4 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.7 ETO13373.1 - 5.2 7.2 7.0 1.8 8.7 1.7 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Myco_arth_vir_N PF09610.5 ETO13374.1 - 1.7 8.6 4.5 4.1 7.4 3.1 1.7 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) DUF1632 PF07857.7 ETO13375.1 - 2.4e-18 66.3 18.3 2.6e-12 46.5 0.3 3.4 3 1 0 3 3 3 2 CEO family (DUF1632) DUF1510 PF07423.6 ETO13375.1 - 0.072 12.4 14.7 0.51 9.6 9.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) CD20 PF04103.10 ETO13375.1 - 0.49 10.3 0.0 0.49 10.3 0.0 3.2 3 2 1 4 4 4 0 CD20-like family Herpes_LMP1 PF05297.6 ETO13375.1 - 1.6 7.5 15.0 3.2 6.5 10.4 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Daxx PF03344.10 ETO13375.1 - 1.7 6.9 22.3 3 6.2 15.4 1.3 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 ETO13375.1 - 4.7 5.1 19.0 8.8 4.2 13.2 1.4 1 0 0 1 1 1 0 CDC45-like protein Vps39_2 PF10367.4 ETO13376.1 - 0.016 15.3 0.6 0.16 12.1 0.0 2.8 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 SR-25 PF10500.4 ETO13376.1 - 0.029 13.8 12.4 0.091 12.2 8.6 1.8 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NAD_binding_6 PF08030.7 ETO13376.1 - 0.031 14.1 2.9 2.3 8.0 0.1 2.9 2 1 0 2 2 2 0 Ferric reductase NAD binding domain Blo-t-5 PF11642.3 ETO13376.1 - 0.19 11.4 4.4 0.87 9.3 0.9 2.7 2 0 0 2 2 2 0 Mite allergen Blo t 5 zf-RING_5 PF14634.1 ETO13376.1 - 0.29 10.8 5.7 0.15 11.8 1.0 2.2 2 0 0 2 2 2 0 zinc-RING finger domain WXG100 PF06013.7 ETO13376.1 - 0.55 10.2 5.0 6 6.9 1.2 3.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG zf-RING_2 PF13639.1 ETO13376.1 - 0.95 9.3 4.5 1.8 8.4 1.3 2.3 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.1 ETO13376.1 - 1.2 9.2 4.7 0.59 10.2 1.2 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO13376.1 - 1.7 8.3 6.2 0.32 10.6 1.5 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF3446 PF11928.3 ETO13376.1 - 4.4 7.5 17.5 0.42 10.8 3.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) YqeY PF09424.5 ETO13377.1 - 0.01 15.6 0.1 0.027 14.3 0.1 1.7 1 0 0 1 1 1 0 Yqey-like protein Cytadhesin_P30 PF07271.6 ETO13378.1 - 0.031 13.5 0.1 0.036 13.3 0.1 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 Bap31 PF05529.7 ETO13378.1 - 0.57 9.6 0.1 0.57 9.6 0.0 2.3 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like SDA1 PF05285.7 ETO13379.1 - 0.02 14.1 2.5 0.017 14.3 1.7 1.0 1 0 0 1 1 1 0 SDA1 WBP-1 PF11669.3 ETO13379.1 - 0.032 14.2 0.9 0.041 13.9 0.6 1.2 1 0 0 1 1 1 0 WW domain-binding protein 1 ATG27 PF09451.5 ETO13379.1 - 0.32 10.2 5.0 0.12 11.6 2.1 1.3 1 1 0 1 1 1 0 Autophagy-related protein 27 NDUF_B4 PF07225.7 ETO13381.1 - 0.041 13.6 2.0 1.3 8.8 0.2 2.4 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) MMPL PF03176.10 ETO13381.1 - 0.046 12.4 0.0 0.065 11.9 0.0 1.2 1 0 0 1 1 1 0 MMPL family DUF3367 PF11847.3 ETO13381.1 - 0.055 11.4 0.0 0.077 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) SPC25 PF06703.6 ETO13381.1 - 0.087 12.4 2.0 0.14 11.7 1.4 1.3 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) ETRAMP PF09716.5 ETO13381.1 - 0.14 12.1 3.2 1.5 8.8 2.2 2.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) YMF19 PF02326.10 ETO13381.1 - 0.33 11.5 6.2 0.23 12.0 2.8 1.8 2 0 0 2 2 2 0 Plant ATP synthase F0 DUF2839 PF10999.3 ETO13381.1 - 6.8 6.8 9.3 11 6.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2839) Cut8_M PF14483.1 ETO13382.1 - 0.057 13.2 1.2 0.25 11.1 0.4 2.3 2 0 0 2 2 2 0 Cut8 dimerisation domain Nop14 PF04147.7 ETO13383.1 - 8e-05 20.7 33.4 8e-05 20.7 23.1 1.0 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 ETO13383.1 - 0.0035 15.4 28.2 0.0039 15.2 19.5 1.1 1 0 0 1 1 1 1 CDC45-like protein SID-1_RNA_chan PF13965.1 ETO13383.1 - 0.89 7.6 8.6 1 7.4 6.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Ycf1 PF05758.7 ETO13383.1 - 2.5 5.7 21.0 2.3 5.8 14.5 1.0 1 0 0 1 1 1 0 Ycf1 Hid1 PF12722.2 ETO13383.1 - 6.2 4.3 19.6 6.4 4.3 13.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Daxx PF03344.10 ETO13383.1 - 9 4.6 45.0 11 4.3 31.2 1.1 1 0 0 1 1 1 0 Daxx Family Kelch_1 PF01344.20 ETO13384.1 - 1.7e-10 40.2 4.6 0.00025 20.5 0.5 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 ETO13384.1 - 1.6e-08 34.3 2.7 0.094 12.9 0.5 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 ETO13384.1 - 2.8e-08 33.3 0.4 0.0076 15.9 0.0 3.6 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO13384.1 - 0.00011 22.2 0.5 0.66 10.2 0.0 4.4 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO13384.1 - 0.00013 21.8 14.1 0.2 11.6 1.4 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO13384.1 - 0.00021 20.9 6.2 0.034 13.9 0.2 4.5 5 1 0 5 5 5 1 Kelch motif Kelch_6 PF13964.1 ETO13385.1 - 6e-10 38.8 2.9 0.00014 21.9 0.1 5.0 4 1 1 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO13385.1 - 2.1e-08 33.6 4.9 2.5e-05 23.7 0.2 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO13385.1 - 3.9e-07 29.5 1.7 0.007 16.0 0.1 5.0 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.1 ETO13385.1 - 1.7e-05 24.4 0.2 0.036 13.8 0.0 4.3 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO13385.1 - 0.00046 20.0 0.2 17 5.5 0.0 4.4 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 ETO13385.1 - 0.016 15.3 0.4 0.52 10.5 0.0 3.5 5 0 0 5 5 5 0 Galactose oxidase, central domain Copper-bind PF00127.15 ETO13385.1 - 0.24 11.6 1.7 3.9 7.7 0.0 2.4 2 0 0 2 2 2 0 Copper binding proteins, plastocyanin/azurin family WD40 PF00400.27 ETO13386.1 - 1.3e-62 205.6 25.6 7.8e-11 41.4 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO13386.1 - 1.6e-12 46.3 8.7 0.018 13.1 0.0 5.3 1 1 4 5 5 5 5 Nucleoporin Nup120/160 DUF605 PF04652.11 ETO13391.1 - 0.051 12.9 0.2 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 Vta1 like DNA_photolyase PF00875.13 ETO13392.1 - 0.077 12.7 0.0 0.099 12.3 0.0 1.1 1 0 0 1 1 1 0 DNA photolyase CDC37_N PF03234.9 ETO13392.1 - 1.3 9.3 7.0 0.29 11.4 2.9 1.4 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding D123 PF07065.9 ETO13393.1 - 3.6e-17 62.3 3.8 7.6e-16 58.0 0.2 2.2 1 1 1 2 2 2 2 D123 DUF4343 PF14243.1 ETO13393.1 - 1e-07 31.8 0.0 1.9e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4343) DUF1336 PF07059.7 ETO13394.1 - 2.8e-37 128.3 0.0 3.8e-35 121.3 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1336) CENP-B_dimeris PF09026.5 ETO13394.1 - 0.025 14.8 0.6 0.025 14.8 0.4 2.6 1 1 0 2 2 2 0 Centromere protein B dimerisation domain Nop14 PF04147.7 ETO13394.1 - 0.032 12.1 17.9 0.045 11.6 12.4 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 ETO13394.1 - 0.37 8.7 19.2 0.035 12.1 9.2 1.8 1 1 1 2 2 2 0 CDC45-like protein Exo_endo_phos PF03372.18 ETO13395.1 - 1.7e-09 37.9 0.0 3.5e-09 36.9 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family GTP_EFTU PF00009.22 ETO13396.1 - 7.2e-49 165.7 0.2 5.3e-48 162.9 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 ETO13396.1 - 5.6e-06 26.3 1.8 1.4e-05 25.1 0.6 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 ETO13396.1 - 1.3e-05 25.0 0.0 0.00018 21.4 0.0 3.0 2 2 0 2 2 2 1 50S ribosome-binding GTPase RGS PF00615.14 ETO13397.1 - 9.2e-08 32.2 7.7 9.2e-08 32.2 5.4 2.4 2 1 0 2 2 2 1 Regulator of G protein signaling domain DUF3616 PF12275.3 ETO13397.1 - 0.16 10.9 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3616) RPEL PF02755.10 ETO13398.1 - 1.9e-14 52.4 11.2 3.3e-05 23.0 0.3 4.1 3 1 0 3 3 3 3 RPEL repeat DUF1882 PF08966.6 ETO13398.1 - 0.11 12.4 1.3 0.26 11.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1882) CBS PF00571.23 ETO13399.1 - 2.9e-15 55.7 0.9 2.9e-11 42.9 0.2 3.0 4 0 0 4 4 4 2 CBS domain DUSP PF06337.7 ETO13400.1 - 1e-06 29.0 1.2 1e-06 29.0 0.8 2.2 2 1 0 2 2 2 1 DUSP domain DUF4120 PF13496.1 ETO13400.1 - 0.25 11.3 3.5 8 6.5 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4120) CENP-B_dimeris PF09026.5 ETO13400.1 - 0.9 9.8 6.6 0.084 13.1 0.9 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain WD40 PF00400.27 ETO13401.1 - 1.5e-20 72.2 3.1 3.3e-10 39.4 0.2 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO13401.1 - 0.0047 15.7 0.3 0.0048 15.7 0.2 1.1 1 0 0 1 1 1 1 Nup133 N terminal like CHZ PF09649.5 ETO13401.1 - 0.14 11.3 0.3 0.24 10.6 0.2 1.4 1 0 0 1 1 1 0 Histone chaperone domain CHZ DREV PF05219.7 ETO13403.1 - 0.077 11.8 0.1 0.69 8.7 0.0 2.0 1 1 0 2 2 2 0 DREV methyltransferase DUF1886 PF09171.5 ETO13403.1 - 0.17 10.8 2.0 0.23 10.4 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1886) DUF1815 PF08844.5 ETO13405.1 - 0.0025 17.3 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1815) DNA_pol_viral_N PF00242.12 ETO13406.1 - 0.24 10.3 28.7 0.55 9.2 3.7 2.1 2 0 0 2 2 2 0 DNA polymerase (viral) N-terminal domain Sulfotransfer_3 PF13469.1 ETO13407.1 - 0.033 15.1 0.1 0.15 13.0 0.1 1.9 1 1 0 1 1 1 0 Sulfotransferase family FAM176 PF14851.1 ETO13408.1 - 0.06 13.0 0.4 0.14 11.8 0.3 1.5 1 0 0 1 1 1 0 FAM176 family TPR_11 PF13414.1 ETO13409.1 - 3.4e-25 87.4 2.6 3.8e-16 58.4 0.2 2.7 1 1 1 2 2 2 2 TPR repeat DnaJ PF00226.26 ETO13409.1 - 1.7e-20 72.4 1.9 3.7e-20 71.4 1.3 1.6 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.12 ETO13409.1 - 2.1e-14 52.2 0.2 0.00097 18.8 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO13409.1 - 4e-11 42.0 0.5 0.017 14.7 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO13409.1 - 3.5e-05 23.6 1.6 1 9.7 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO13409.1 - 7.6e-05 23.0 0.0 0.28 11.9 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO13409.1 - 0.0013 18.3 2.1 0.41 10.5 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO13409.1 - 0.05 14.2 0.2 3.4 8.4 0.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.27 ETO13410.1 - 6.1e-54 178.0 19.5 6.3e-12 44.9 0.4 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO13410.1 - 9.7e-11 40.4 2.2 0.0015 16.7 0.2 4.6 1 1 4 5 5 5 3 Nucleoporin Nup120/160 Ole-e-6 PF09253.5 ETO13410.1 - 0.34 10.5 2.5 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 Pollen allergen ole e 6 EF_assoc_1 PF08355.7 ETO13411.1 - 7.4e-09 34.7 0.3 1.5e-08 33.7 0.2 1.5 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 ETO13411.1 - 0.00039 19.8 0.0 0.00091 18.6 0.0 1.6 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO13411.1 - 0.01 16.3 0.0 0.051 14.0 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein WD40 PF00400.27 ETO13412.1 - 2.6e-07 30.2 0.3 0.00034 20.3 0.0 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Metallophos_2 PF12850.2 ETO13413.1 - 5e-10 39.4 0.1 8e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 ETO13413.1 - 1.3e-07 31.1 11.7 3e-06 26.7 8.1 2.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase YolD PF08863.5 ETO13413.1 - 0.0057 16.4 0.2 0.11 12.3 0.0 2.3 2 0 0 2 2 2 1 YolD-like protein E1-E2_ATPase PF00122.15 ETO13414.1 - 2.5e-05 23.4 0.2 7.8e-05 21.8 0.0 1.8 2 1 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 ETO13414.1 - 0.014 15.5 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Macoilin PF09726.4 ETO13415.1 - 0.069 11.4 31.5 0.082 11.1 21.9 1.0 1 0 0 1 1 1 0 Transmembrane protein UreE_C PF05194.7 ETO13415.1 - 4 7.6 15.5 0.54 10.3 5.6 2.5 2 0 0 2 2 2 0 UreE urease accessory protein, C-terminal domain Membralin PF09746.4 ETO13415.1 - 9.7 5.1 8.5 14 4.5 5.9 1.3 1 0 0 1 1 1 0 Tumour-associated protein MIP-T3 PF10243.4 ETO13416.1 - 0.7 8.2 52.8 1.2 7.5 36.6 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 ATG16 PF08614.6 ETO13417.1 - 0.0038 17.0 16.4 0.0038 17.0 11.3 2.8 2 1 0 2 2 2 1 Autophagy protein 16 (ATG16) Pox_A_type_inc PF04508.7 ETO13417.1 - 6.7 6.7 8.6 3.1 7.8 0.9 4.0 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat PIRT PF15099.1 ETO13418.1 - 1.3 8.2 3.5 3.6 6.8 2.4 1.8 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family AAA PF00004.24 ETO13419.1 - 8.7e-06 25.9 0.0 2.8e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 ETO13419.1 - 0.0013 17.8 0.0 0.0019 17.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 ETO13419.1 - 0.0065 15.9 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 ETO13419.1 - 0.011 15.8 0.0 0.055 13.6 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.1 ETO13419.1 - 0.013 15.4 0.0 0.063 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 ETO13419.1 - 0.037 13.6 0.0 0.1 12.2 0.0 1.8 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 ETO13419.1 - 0.061 12.7 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.8 ETO13419.1 - 0.061 12.0 0.1 0.12 11.0 0.1 1.5 1 1 0 1 1 1 0 TIP49 C-terminus AAA_5 PF07728.9 ETO13419.1 - 0.076 12.7 0.0 0.55 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SMC_N PF02463.14 ETO13419.1 - 0.085 12.0 0.0 0.19 10.9 0.0 1.6 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 ETO13419.1 - 0.11 12.6 0.2 1.8 8.6 0.0 2.6 2 1 0 3 3 3 0 AAA domain AAA_29 PF13555.1 ETO13419.1 - 0.11 11.9 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain HCV_NS2 PF01538.13 ETO13420.1 - 0.025 14.0 0.4 0.032 13.6 0.3 1.1 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS2 DUF1700 PF08006.6 ETO13420.1 - 1.7 7.9 5.5 1.2 8.4 2.6 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1700) RGS PF00615.14 ETO13421.1 - 1.5e-09 38.0 1.1 1.7e-07 31.3 0.7 2.6 1 1 0 1 1 1 1 Regulator of G protein signaling domain Rsbr_N PF08678.5 ETO13421.1 - 0.23 11.3 2.2 5.3 6.9 0.1 2.8 2 1 0 2 2 2 0 Rsbr N terminal E_Pc_C PF06752.7 ETO13422.1 - 0.28 10.6 9.0 0.3 10.5 6.3 1.1 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus PAT1 PF09770.4 ETO13422.1 - 6.8 4.7 16.1 7 4.7 11.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Exo_endo_phos PF03372.18 ETO13423.1 - 7.9e-06 25.9 0.0 2.5e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4658 PF15555.1 ETO13423.1 - 0.039 13.8 0.1 0.21 11.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) U-box PF04564.10 ETO13424.1 - 2.3e-20 72.3 0.8 8.1e-20 70.5 0.1 2.4 2 0 0 2 2 2 1 U-box domain zf-Nse PF11789.3 ETO13424.1 - 0.004 16.6 0.2 0.012 15.1 0.1 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Trypan_PARP PF05887.6 ETO13424.1 - 0.16 11.8 0.0 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) ABC_membrane PF00664.18 ETO13426.1 - 1.2e-12 47.8 13.6 1.7e-12 47.3 9.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF1631 PF07793.6 ETO13427.1 - 2.2 6.3 5.5 13 3.8 3.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1631) P4Ha_N PF08336.6 ETO13429.1 - 0.95 9.2 4.2 17 5.2 0.0 2.3 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Abhydrolase_5 PF12695.2 ETO13430.1 - 8.1e-15 54.8 0.0 2.9e-14 53.0 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family NUDIX PF00293.23 ETO13430.1 - 7e-11 41.9 0.0 1.5e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Abhydrolase_6 PF12697.2 ETO13430.1 - 1.3e-08 34.9 0.0 0.00042 20.2 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETO13430.1 - 6.5e-06 25.5 0.0 1.9e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 ETO13430.1 - 0.00032 20.2 0.7 0.76 9.1 0.0 2.5 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 ETO13430.1 - 0.0011 18.6 0.1 1.3 8.5 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.13 ETO13430.1 - 0.042 13.1 0.1 0.095 11.9 0.0 1.6 1 0 0 1 1 1 0 Dienelactone hydrolase family Pex16 PF08610.5 ETO13430.1 - 0.88 8.5 0.0 0.88 8.5 0.0 2.5 2 1 0 2 2 2 0 Peroxisomal membrane protein (Pex16) Menin PF05053.8 ETO13430.1 - 4.9 5.1 12.1 10 4.1 8.4 1.4 1 0 0 1 1 1 0 Menin ASF1_hist_chap PF04729.8 ETO13431.1 - 7.5e-50 168.5 0.2 8.7e-50 168.3 0.1 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone GFA PF04828.9 ETO13432.1 - 3.9e-05 23.5 2.8 5.4e-05 23.0 0.6 2.2 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme HATPase_c_3 PF13589.1 ETO13432.1 - 0.0023 17.5 0.3 0.0047 16.5 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Gal-3-0_sulfotr PF06990.6 ETO13434.1 - 0.046 12.3 0.1 0.053 12.1 0.1 1.1 1 0 0 1 1 1 0 Galactose-3-O-sulfotransferase DUF2281 PF10047.4 ETO13434.1 - 0.083 13.1 0.2 7.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2281) DUF896 PF05979.7 ETO13436.1 - 0.013 15.1 0.3 0.028 14.0 0.2 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) Sec62 PF03839.11 ETO13436.1 - 1.4 8.2 6.3 0.31 10.4 2.0 1.6 2 0 0 2 2 2 0 Translocation protein Sec62 Presenilin PF01080.12 ETO13436.1 - 7.6 5.2 7.4 8.2 5.1 5.1 1.3 1 0 0 1 1 1 0 Presenilin Mucin PF01456.12 ETO13437.1 - 0.0099 15.6 0.0 0.018 14.7 0.0 1.3 1 1 0 1 1 1 1 Mucin-like glycoprotein Caenor_Her-1 PF09232.5 ETO13437.1 - 0.015 15.3 0.4 0.015 15.3 0.3 1.8 2 1 0 2 2 2 0 Caenorhabditis elegans Her-1 GlnD_UR_UTase PF08335.6 ETO13437.1 - 0.045 13.6 0.1 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 GlnD PII-uridylyltransferase HI0933_like PF03486.9 ETO13437.1 - 0.19 10.1 2.0 0.22 9.9 1.4 1.1 1 0 0 1 1 1 0 HI0933-like protein Cullin PF00888.17 ETO13438.1 - 1.7e-83 281.1 17.9 5.4e-82 276.2 12.4 2.1 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 ETO13438.1 - 4.8e-23 80.7 1.8 1.8e-22 78.9 0.1 2.9 3 0 0 3 3 3 1 Cullin protein neddylation domain Med15_fungi PF05397.7 ETO13438.1 - 0.0072 16.2 3.4 0.008 16.1 0.7 2.4 2 0 0 2 2 2 1 Mediator complex subunit 15 PAT1 PF09770.4 ETO13439.1 - 1.7 6.8 62.3 2.2 6.4 43.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4137 PF13593.1 ETO13440.1 - 4.6e-33 114.6 4.5 5.4e-33 114.4 3.1 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) DUF46 PF01864.12 ETO13440.1 - 0.02 14.8 2.9 0.02 14.8 2.0 1.9 2 1 1 3 3 3 0 Putative integral membrane protein DUF46 RDD PF06271.7 ETO13440.1 - 0.16 11.8 5.5 0.08 12.8 1.4 2.0 2 0 0 2 2 2 0 RDD family DUF2791 PF10923.3 ETO13441.1 - 0.011 14.3 0.0 0.014 14.0 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) CDO_I PF05995.7 ETO13443.1 - 1.9e-13 49.9 0.1 1.6e-12 46.9 0.1 2.1 1 1 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 ETO13443.1 - 0.007 15.7 0.1 0.017 14.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1637) NicO PF03824.11 ETO13444.1 - 5.6 6.1 5.7 3.1 7.0 2.3 1.6 2 0 0 2 2 2 0 High-affinity nickel-transport protein WD40 PF00400.27 ETO13445.1 - 2e-77 252.5 21.5 4.8e-13 48.4 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO13445.1 - 1.7e-08 34.3 0.5 0.0088 15.7 0.0 3.0 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO13445.1 - 2e-05 22.9 8.3 0.023 12.8 0.3 4.5 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO13445.1 - 0.00055 18.3 0.6 0.72 8.0 0.0 2.8 2 1 1 3 3 3 3 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO13445.1 - 0.00065 18.5 5.8 0.22 10.2 0.0 4.4 2 2 4 6 6 6 2 Nup133 N terminal like PD40 PF07676.7 ETO13445.1 - 0.003 17.1 7.6 3.8 7.2 0.1 4.5 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 ETO13445.1 - 0.031 13.3 2.0 0.86 8.6 0.1 3.4 2 1 1 4 4 4 0 Protein of unknown function (DUF1258) Methyltransf_12 PF08242.7 ETO13446.1 - 7.4 7.1 10.6 8.1 6.9 0.8 2.5 2 0 0 2 2 2 0 Methyltransferase domain Pex14_N PF04695.8 ETO13446.1 - 9.3 6.2 14.1 4.2 7.4 3.1 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF420 PF04238.7 ETO13447.1 - 0.00063 19.7 9.0 0.02 14.8 0.5 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF420) DASH_Dad3 PF08656.5 ETO13447.1 - 0.053 13.2 0.2 0.13 11.9 0.1 1.6 1 0 0 1 1 1 0 DASH complex subunit Dad3 DUF4519 PF15012.1 ETO13447.1 - 2.4 8.1 4.4 23 4.9 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4519) Sfi1_C PF10638.4 ETO13448.1 - 0.049 14.0 1.2 0.15 12.5 0.1 2.2 2 0 0 2 2 2 0 Spindle body associated protein C-terminus Mucin PF01456.12 ETO13449.1 - 0.16 11.7 0.1 0.16 11.7 0.1 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein PMC2NT PF08066.7 ETO13450.1 - 0.031 14.5 0.2 0.031 14.5 0.2 3.0 3 1 1 4 4 4 0 PMC2NT (NUC016) domain GAS PF13851.1 ETO13450.1 - 0.15 11.2 3.3 0.28 10.3 2.3 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF1777 PF08648.7 ETO13451.1 - 0.34 10.6 24.1 0.51 10.0 16.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) HECT PF00632.20 ETO13452.1 - 1.3e-35 123.0 2.3 1.3e-35 123.0 1.6 1.5 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Herpes_capsid PF06112.6 ETO13455.1 - 0.033 14.2 0.7 0.094 12.7 0.2 1.9 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein TOM13 PF08219.6 ETO13456.1 - 0.044 13.5 0.4 0.26 11.0 0.0 2.4 2 0 0 2 2 2 0 Outer membrane protein TOM13 DUF2461 PF09365.5 ETO13459.1 - 0.31 10.4 9.4 0.057 12.8 2.7 2.0 2 0 0 2 2 2 0 Conserved hypothetical protein (DUF2461) DUF1820 PF08850.6 ETO13459.1 - 0.5 10.4 5.0 0.38 10.8 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1820) Trypan_PARP PF05887.6 ETO13461.1 - 3.1 7.6 4.6 12 5.7 3.2 1.9 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) WD40 PF00400.27 ETO13462.1 - 4.6e-39 130.9 12.1 2e-12 46.4 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO13462.1 - 4.7e-07 29.6 7.5 0.015 15.4 0.0 5.0 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO13462.1 - 0.0019 17.7 5.3 0.12 11.9 0.3 3.9 3 0 0 3 3 3 1 Kelch motif PD40 PF07676.7 ETO13462.1 - 0.013 15.1 2.6 2.7 7.7 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO13462.1 - 0.024 12.7 1.0 0.93 7.5 0.1 2.9 1 1 3 4 4 4 0 Nucleoporin Nup120/160 Kelch_3 PF13415.1 ETO13462.1 - 0.032 14.4 0.0 14 6.0 0.0 3.5 3 0 0 3 3 3 0 Galactose oxidase, central domain Cullin PF00888.17 ETO13463.1 - 7.4e-93 312.0 21.4 7.6e-62 209.6 10.7 2.9 2 1 0 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.4 ETO13464.1 - 7.7e-26 89.7 3.5 1.4e-25 88.9 2.4 1.4 1 0 0 1 1 1 1 Cullin protein neddylation domain Cullin PF00888.17 ETO13464.1 - 0.0005 18.7 0.7 0.0008 18.0 0.0 1.6 1 1 0 1 1 1 1 Cullin family DUF3658 PF12395.3 ETO13464.1 - 0.044 13.3 0.6 0.062 12.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function CRAL_TRIO_N PF03765.10 ETO13464.1 - 0.048 13.7 0.1 0.47 10.6 0.0 2.2 2 0 0 2 2 2 0 CRAL/TRIO, N-terminal domain DUF3139 PF11337.3 ETO13464.1 - 1 9.7 4.4 0.38 11.0 0.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3139) Wbp11 PF09429.5 ETO13467.1 - 0.37 10.8 7.3 0.53 10.2 5.0 1.3 1 1 0 1 1 1 0 WW domain binding protein 11 DNA_pol3_a_NII PF11490.3 ETO13467.1 - 0.66 9.6 4.9 4.1 7.0 0.1 2.1 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II HA PF03457.9 ETO13469.1 - 0.0036 17.3 0.0 0.015 15.3 0.0 2.2 1 0 0 1 1 1 1 Helicase associated domain Thymidylate_kin PF02223.12 ETO13469.1 - 0.033 13.5 0.2 0.082 12.2 0.1 1.6 1 0 0 1 1 1 0 Thymidylate kinase tRNA-synt_His PF13393.1 ETO13470.1 - 0.023 13.7 1.6 0.028 13.5 1.1 1.2 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Fumble PF03630.9 ETO13470.1 - 0.072 11.9 4.5 0.077 11.8 3.1 1.3 1 0 0 1 1 1 0 Fumble Virulence_fact PF13769.1 ETO13470.1 - 0.086 12.7 4.1 0.23 11.3 0.4 2.4 1 1 1 2 2 2 0 Virulence factor DUF842 PF05811.8 ETO13470.1 - 0.088 12.2 6.1 0.14 11.6 4.2 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF87 PF01935.12 ETO13470.1 - 0.091 12.5 4.4 0.11 12.2 2.9 1.3 1 1 0 1 1 1 0 Domain of unknown function DUF87 THP2 PF09432.5 ETO13470.1 - 0.12 12.2 6.3 0.64 9.8 4.4 1.9 1 1 0 1 1 1 0 Tho complex subunit THP2 ACR_tran PF00873.14 ETO13470.1 - 0.12 9.7 6.2 0.14 9.4 4.3 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family DUF1974 PF09317.6 ETO13470.1 - 0.15 11.4 5.1 0.18 11.1 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) Fib_alpha PF08702.5 ETO13470.1 - 0.16 12.0 15.2 0.03 14.4 5.0 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1539 PF07560.6 ETO13470.1 - 0.17 11.7 5.9 2.6 7.9 1.1 2.2 1 1 0 2 2 2 0 Domain of Unknown Function (DUF1539) TORC_M PF12885.2 ETO13470.1 - 0.17 11.6 0.6 0.27 11.0 0.4 1.3 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain Miro PF08477.8 ETO13470.1 - 0.21 12.1 3.4 0.15 12.5 1.0 1.7 1 1 1 2 2 2 0 Miro-like protein CART PF06373.6 ETO13470.1 - 0.29 11.0 1.5 0.6 10.0 0.8 1.7 1 1 0 1 1 1 0 Cocaine and amphetamine regulated transcript protein (CART) RE_Alw26IDE PF09665.5 ETO13470.1 - 0.39 9.3 9.0 0.46 9.1 6.2 1.1 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) Med30 PF11315.3 ETO13470.1 - 0.52 10.4 14.4 2.6 8.1 1.4 2.2 1 1 1 2 2 2 0 Mediator complex subunit 30 ParB PF08775.5 ETO13470.1 - 0.63 10.3 11.2 0.23 11.7 3.9 2.2 1 1 1 2 2 2 0 ParB family APG6 PF04111.7 ETO13470.1 - 0.64 9.0 11.7 0.77 8.7 8.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 P4Ha_N PF08336.6 ETO13470.1 - 0.68 9.7 6.9 0.78 9.5 3.6 2.0 1 1 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF3349 PF11829.3 ETO13470.1 - 0.81 10.1 3.6 0.54 10.7 0.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3349) IncA PF04156.9 ETO13470.1 - 0.82 9.2 11.9 1.2 8.6 8.2 1.4 1 1 0 1 1 1 0 IncA protein IZUMO PF15005.1 ETO13470.1 - 1 9.4 8.2 1.4 8.9 5.7 1.1 1 0 0 1 1 1 0 Izumo sperm-egg fusion ING PF12998.2 ETO13470.1 - 1.4 9.2 13.4 4 7.7 0.3 2.3 1 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Cauli_AT PF03233.8 ETO13470.1 - 1.6 8.4 11.0 0.96 9.1 5.8 1.9 1 1 1 2 2 2 0 Aphid transmission protein TMPIT PF07851.8 ETO13470.1 - 1.6 7.7 9.6 1.9 7.5 6.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein Merozoite_SPAM PF07133.6 ETO13470.1 - 1.9 8.3 12.2 4.2 7.2 8.5 1.5 1 1 0 1 1 1 0 Merozoite surface protein (SPAM) Allexi_40kDa PF05549.6 ETO13470.1 - 2.3 7.4 8.0 3.5 6.8 5.5 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein Atg14 PF10186.4 ETO13470.1 - 2.5 6.9 11.1 3 6.7 7.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Caudo_TAP PF02413.12 ETO13470.1 - 2.7 8.1 6.5 5.8 7.0 4.5 1.7 1 1 0 1 1 1 0 Caudovirales tail fibre assembly protein DUF2203 PF09969.4 ETO13470.1 - 2.8 8.2 7.3 3.3 7.9 4.0 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Med4 PF10018.4 ETO13470.1 - 5.3 6.4 10.4 1 8.7 4.6 1.7 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF948 PF06103.6 ETO13470.1 - 6.6 6.6 12.6 2.7 7.9 3.6 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Spectrin PF00435.16 ETO13470.1 - 9.9 6.5 11.5 7.2 6.9 3.2 2.7 1 1 1 2 2 2 0 Spectrin repeat Dynamin_N PF00350.18 ETO13471.1 - 1.9e-16 60.3 0.0 2.3e-14 53.5 0.0 2.2 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 ETO13471.1 - 1.6e-05 24.8 0.0 4.2e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 ETO13471.1 - 0.00025 21.5 0.0 0.00041 20.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 ETO13471.1 - 0.0098 15.8 0.0 0.02 14.8 0.0 1.5 2 0 0 2 2 2 1 AAA domain DUF927 PF06048.6 ETO13471.1 - 0.028 13.6 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF927) MobB PF03205.9 ETO13471.1 - 0.034 13.8 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 ETO13471.1 - 0.074 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Abhydrolase_6 PF12697.2 ETO13472.1 - 8.3e-16 58.5 0.0 2.2e-15 57.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETO13472.1 - 1.4e-07 31.3 0.0 8.5e-07 28.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETO13472.1 - 3.4e-07 30.1 0.0 0.0046 16.7 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Esterase PF00756.15 ETO13472.1 - 4e-05 23.1 0.0 9.5e-05 21.9 0.0 1.7 2 0 0 2 2 2 1 Putative esterase SPX PF03105.14 ETO13472.1 - 0.00028 20.7 1.4 0.00028 20.7 1.0 1.8 2 0 0 2 2 2 1 SPX domain DLH PF01738.13 ETO13472.1 - 0.0037 16.5 0.3 2.7 7.1 0.1 2.7 2 1 1 3 3 3 2 Dienelactone hydrolase family UPF0227 PF05728.7 ETO13472.1 - 0.015 15.0 0.3 0.03 14.0 0.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Esterase_phd PF10503.4 ETO13472.1 - 0.018 14.2 0.1 0.031 13.5 0.1 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase Tap-RNA_bind PF09162.5 ETO13472.1 - 0.039 13.5 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 Tap, RNA-binding Myc_N PF01056.13 ETO13472.1 - 0.22 10.6 3.6 0.071 12.2 0.3 1.8 2 0 0 2 2 2 0 Myc amino-terminal region DUF3439 PF11921.3 ETO13472.1 - 0.37 10.5 5.2 0.84 9.4 3.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Pex14_N PF04695.8 ETO13472.1 - 6.8 6.7 12.1 6.6 6.7 3.7 2.7 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ion_trans PF00520.26 ETO13473.1 - 1.9e-05 23.9 1.3 5.9e-05 22.3 0.3 2.0 2 0 0 2 2 2 1 Ion transport protein DUF4097 PF13349.1 ETO13474.1 - 0.012 15.1 0.2 0.02 14.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) Mnd1 PF03962.10 ETO13474.1 - 0.21 11.2 6.7 0.35 10.5 4.6 1.3 1 0 0 1 1 1 0 Mnd1 family WD40 PF00400.27 ETO13475.1 - 3.2e-40 134.5 20.8 3.4e-10 39.4 0.0 7.0 6 1 1 7 7 7 5 WD domain, G-beta repeat zf-TRAF PF02176.13 ETO13475.1 - 2.8e-07 30.7 2.5 1.5e-06 28.5 1.7 2.3 1 0 0 1 1 1 1 TRAF-type zinc finger Cep57_CLD_2 PF14197.1 ETO13475.1 - 0.0075 16.1 3.5 0.0075 16.1 2.4 3.1 2 1 0 2 2 2 1 Centrosome localisation domain of PPC89 PX PF00787.19 ETO13476.1 - 0.0004 20.1 3.6 0.00086 19.0 0.6 2.8 3 0 0 3 3 3 1 PX domain Solute_trans_a PF03619.11 ETO13477.1 - 1.9e-12 47.0 5.4 6.8e-12 45.2 3.5 1.9 1 1 0 1 1 1 1 Organic solute transporter Ostalpha Rcd1 PF04078.8 ETO13478.1 - 3.7e-82 275.0 3.4 2.4e-36 124.9 0.0 4.0 3 1 0 3 3 3 3 Cell differentiation family, Rcd1-like DUF2003 PF09404.5 ETO13478.1 - 0.018 13.4 0.2 0.028 12.8 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF2003) Cytadhesin_P30 PF07271.6 ETO13478.1 - 0.71 9.1 7.8 1.4 8.1 5.4 1.4 1 0 0 1 1 1 0 Cytadhesin P30/P32 DUF2417 PF10329.4 ETO13479.1 - 0.068 12.5 0.2 0.075 12.4 0.2 1.1 1 0 0 1 1 1 0 Region of unknown function (DUF2417) DUF1168 PF06658.7 ETO13479.1 - 0.22 11.0 10.1 0.29 10.6 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) zf-RanBP PF00641.13 ETO13480.1 - 1.5e-06 27.2 1.1 3.2e-06 26.1 0.8 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Ran_BP1 PF00638.13 ETO13480.1 - 0.00037 20.5 0.5 0.0096 15.9 0.2 2.8 2 1 0 2 2 2 1 RanBP1 domain Herpes_capsid PF06112.6 ETO13481.1 - 0.4 10.7 8.2 0.54 10.2 5.7 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Pentapeptide PF00805.17 ETO13482.1 - 5.3e-40 134.0 19.7 2.1e-08 33.2 0.0 6.2 3 2 4 7 7 7 7 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO13482.1 - 2.7e-35 120.0 57.0 5.3e-11 42.1 6.7 4.9 1 1 3 5 5 5 5 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 ETO13482.1 - 9.9e-27 92.5 26.8 1.8e-06 27.6 0.3 5.5 4 1 1 5 5 5 5 Pentapeptide repeats (9 copies) CfAFP PF05264.6 ETO13482.1 - 0.0053 16.5 4.6 0.26 11.0 0.1 3.0 2 1 1 3 3 3 2 Choristoneura fumiferana antifreeze protein (CfAFP) Pentapeptide_4 PF13599.1 ETO13483.1 - 6.5e-22 77.1 22.3 3.5e-12 45.9 3.6 2.3 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETO13483.1 - 1e-18 66.1 6.1 3.6e-10 38.8 0.6 3.4 1 1 1 3 3 3 3 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 ETO13483.1 - 2e-10 40.3 15.3 2.1e-08 33.9 2.2 2.7 2 1 1 3 3 3 2 Pentapeptide repeats (9 copies) V_ATPase_I PF01496.14 ETO13483.1 - 4.8 4.8 16.0 6.5 4.4 11.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RNase_H PF00075.19 ETO13485.1 - 0.073 13.4 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 RNase H RVT_3 PF13456.1 ETO13485.1 - 0.12 12.1 0.2 1.1 9.1 0.0 2.5 2 1 1 3 3 3 0 Reverse transcriptase-like Nse4_C PF08743.5 ETO13488.1 - 9.2e-19 67.2 4.6 4.5e-18 65.0 0.9 3.2 2 1 0 2 2 2 1 Nse4 C-terminal LINES_C PF14695.1 ETO13489.1 - 0.11 11.7 0.1 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 Lines C-terminus Staphylokinase PF02821.11 ETO13489.1 - 0.16 11.7 3.3 0.21 11.3 2.3 1.1 1 0 0 1 1 1 0 Staphylokinase/Streptokinase family NUDIX PF00293.23 ETO13489.1 - 0.23 11.1 1.2 0.27 10.8 0.9 1.2 1 0 0 1 1 1 0 NUDIX domain YqfQ PF14181.1 ETO13489.1 - 0.24 11.4 4.1 0.28 11.2 2.8 1.1 1 0 0 1 1 1 0 YqfQ-like protein SelP_N PF04592.9 ETO13489.1 - 0.32 10.3 3.0 0.36 10.1 2.1 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF2890 PF11081.3 ETO13489.1 - 0.37 10.8 6.5 0.42 10.6 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Ycf1 PF05758.7 ETO13489.1 - 0.58 7.8 2.5 0.62 7.7 1.7 1.0 1 0 0 1 1 1 0 Ycf1 TRAP_alpha PF03896.11 ETO13489.1 - 0.89 8.5 4.1 0.93 8.4 2.8 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Daxx PF03344.10 ETO13489.1 - 1.9 6.8 8.7 2.1 6.7 6.0 1.0 1 0 0 1 1 1 0 Daxx Family PH PF00169.24 ETO13490.1 - 1e-11 44.9 7.5 4.9e-10 39.5 5.2 2.3 1 1 0 1 1 1 1 PH domain PH_11 PF15413.1 ETO13490.1 - 8.7e-09 35.6 1.9 1.1e-05 25.6 0.2 2.6 2 0 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 ETO13490.1 - 0.00029 20.8 0.3 0.0097 15.9 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain DUF1908 PF08926.6 ETO13490.1 - 0.053 12.2 2.0 0.083 11.6 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) PPTA PF01239.17 ETO13490.1 - 0.081 12.3 0.1 0.18 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat Mcp5_PH PF12814.2 ETO13490.1 - 0.17 11.7 2.0 0.37 10.7 0.0 2.1 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology DUF4551 PF15087.1 ETO13490.1 - 1 7.6 8.9 1.3 7.2 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PPP4R2 PF09184.6 ETO13490.1 - 1.1 8.7 16.0 1.5 8.3 11.1 1.1 1 0 0 1 1 1 0 PPP4R2 DUF273 PF03314.9 ETO13491.1 - 0.011 15.0 0.9 0.26 10.5 0.0 3.0 2 1 0 3 3 3 0 Protein of unknown function, DUF273 DUF3683 PF12447.3 ETO13492.1 - 0.009 15.8 2.1 1.9 8.3 0.3 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3683) Phosphodiest PF01663.17 ETO13493.1 - 1.4e-09 37.7 1.0 2.3e-09 37.0 0.7 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 ETO13493.1 - 0.012 15.0 3.4 0.019 14.3 1.6 1.7 2 0 0 2 2 2 0 Metalloenzyme superfamily 2-Hacid_dh_C PF02826.14 ETO13494.1 - 1.2e-17 63.6 0.1 1.8e-17 63.0 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FerB PF08150.7 ETO13494.1 - 0.11 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 FerB (NUC096) domain CRISPR_assoc PF08798.6 ETO13495.1 - 0.044 13.5 0.6 0.058 13.1 0.4 1.2 1 0 0 1 1 1 0 CRISPR associated protein Pox_P4B PF03292.9 ETO13496.1 - 0.012 13.5 4.9 0.015 13.2 3.4 1.2 1 0 0 1 1 1 0 Poxvirus P4B major core protein Ndc1_Nup PF09531.5 ETO13496.1 - 7.1 4.9 11.9 8.6 4.6 8.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAM60A PF15396.1 ETO13497.1 - 0.13 12.0 6.4 0.15 11.7 4.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A CDC45 PF02724.9 ETO13497.1 - 0.47 8.4 7.0 0.51 8.3 4.9 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF912 PF06024.7 ETO13497.1 - 0.62 10.1 5.5 4.2 7.4 3.8 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CRT10 PF08728.5 ETO13497.1 - 6.7 4.5 8.8 7.7 4.3 6.1 1.0 1 0 0 1 1 1 0 CRT10 EF-hand_1 PF00036.27 ETO13499.1 - 4.4e-32 106.9 21.5 4.1e-08 31.9 0.5 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 ETO13499.1 - 1.3e-30 105.3 15.4 2.4e-16 59.5 2.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO13499.1 - 1.1e-27 93.3 11.5 4.8e-08 32.2 0.3 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 ETO13499.1 - 1.1e-24 85.8 18.6 1.6e-12 46.8 2.1 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 ETO13499.1 - 6.4e-23 79.0 19.1 5.6e-06 25.4 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 ETO13499.1 - 4e-15 55.4 1.1 1.6e-07 31.1 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 ETO13499.1 - 7.5e-07 29.1 4.9 0.0026 17.7 0.5 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 ETO13499.1 - 2.4e-06 27.2 16.9 0.002 17.8 2.3 3.1 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand TerB PF05099.8 ETO13499.1 - 0.00013 21.6 0.4 0.071 12.8 0.1 2.2 2 0 0 2 2 2 2 Tellurite resistance protein TerB EF-hand_10 PF14788.1 ETO13499.1 - 0.0049 16.5 7.5 0.55 9.9 0.2 2.9 2 2 2 4 4 4 2 EF hand Caleosin PF05042.8 ETO13499.1 - 0.019 14.5 0.2 5.1 6.6 0.1 2.7 2 1 1 3 3 3 0 Caleosin related protein DUF1296 PF06972.6 ETO13499.1 - 0.11 12.5 0.2 0.71 9.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) Toprim_2 PF13155.1 ETO13499.1 - 0.42 10.9 4.6 3.4 8.0 0.3 2.4 1 1 1 2 2 2 0 Toprim-like Potyvirid-P3 PF13608.1 ETO13499.1 - 3.7 6.5 7.3 1.7 7.6 0.8 2.1 2 0 0 2 2 2 0 Protein P3 of Potyviral polyprotein PseudoU_synth_2 PF00849.17 ETO13501.1 - 5.8e-23 81.5 0.1 5.8e-23 81.5 0.1 2.0 2 0 0 2 2 2 1 RNA pseudouridylate synthase Sec62 PF03839.11 ETO13501.1 - 4.8 6.5 12.1 7.2 5.9 8.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 CDC45 PF02724.9 ETO13501.1 - 7.1 4.5 10.7 9.4 4.1 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein NUFIP1 PF10453.4 ETO13504.1 - 0.0078 15.6 0.1 0.0078 15.6 0.1 3.0 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) DUF1385 PF07136.6 ETO13504.1 - 0.088 11.8 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) Pox_P21 PF05313.7 ETO13504.1 - 0.17 11.1 0.1 0.17 11.1 0.1 1.6 2 0 0 2 2 2 0 Poxvirus P21 membrane protein Sex_peptide PF08138.6 ETO13504.1 - 6.7 6.6 5.1 48 3.8 0.4 3.4 3 0 0 3 3 3 0 Sex peptide (SP) family CAP_GLY PF01302.20 ETO13506.1 - 5.4e-11 42.0 4.5 1.9e-08 33.8 1.2 2.7 2 1 0 2 2 2 2 CAP-Gly domain Pyr_redox_2 PF07992.9 ETO13507.1 - 2e-18 67.0 0.2 2.1e-18 66.9 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 ETO13507.1 - 1.3e-10 40.9 0.5 1.4e-10 40.8 0.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 ETO13507.1 - 3.2e-10 39.4 0.7 3.7e-10 39.2 0.5 1.0 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 ETO13507.1 - 1.1e-06 27.7 3.4 1.5e-06 27.3 2.4 1.1 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 ETO13507.1 - 4e-05 22.8 0.0 4.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 ETO13507.1 - 0.00011 20.8 1.8 0.00014 20.5 1.2 1.1 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 ETO13507.1 - 0.00011 22.1 0.7 0.00015 21.7 0.5 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETO13507.1 - 0.00039 19.4 0.5 0.00041 19.3 0.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETO13507.1 - 0.0017 18.6 0.7 0.0036 17.6 0.5 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETO13507.1 - 0.0083 15.0 0.7 0.011 14.7 0.5 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 ETO13507.1 - 0.022 14.7 0.1 0.023 14.7 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 ETO13507.1 - 0.16 10.9 1.5 0.22 10.5 1.0 1.1 1 0 0 1 1 1 0 FAD binding domain THRAP3_BCLAF1 PF15440.1 ETO13510.1 - 0.055 12.1 10.3 0.075 11.6 7.1 1.0 1 0 0 1 1 1 0 THRAP3/BCLAF1 family DUF2457 PF10446.4 ETO13510.1 - 2.1 7.0 19.8 0.16 10.7 10.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.5 ETO13510.1 - 5.2 7.3 9.9 16 5.7 6.0 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF2243 PF10002.4 ETO13511.1 - 0.0094 15.7 2.2 0.022 14.5 1.5 1.6 1 0 0 1 1 1 1 Predicted membrane protein (DUF2243) DUF4064 PF13273.1 ETO13511.1 - 0.22 11.6 10.6 0.33 11.0 2.4 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Kinesin PF00225.18 ETO13512.1 - 3.9e-85 285.5 0.0 4.7e-85 285.2 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain ResIII PF04851.10 ETO13512.1 - 0.11 12.3 0.2 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Rhomboid PF01694.17 ETO13515.1 - 6e-12 45.8 0.5 6e-12 45.8 0.4 2.3 3 0 0 3 3 3 1 Rhomboid family HORMA PF02301.13 ETO13516.1 - 0.068 12.6 0.2 0.089 12.2 0.1 1.2 1 0 0 1 1 1 0 HORMA domain zf-DHHC PF01529.15 ETO13517.1 - 1.9e-08 33.9 47.3 3e-08 33.2 26.3 3.8 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF3816 PF12822.2 ETO13517.1 - 0.002 18.0 13.8 0.0097 15.8 9.5 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3816) FA_desaturase PF00487.19 ETO13517.1 - 0.091 12.1 3.6 0.58 9.5 0.1 2.2 2 0 0 2 2 2 0 Fatty acid desaturase RNase_H PF00075.19 ETO13518.1 - 1.2e-18 67.7 0.0 1.8e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 RNase H Lipase_GDSL_3 PF14606.1 ETO13518.1 - 0.11 12.2 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family RVT_3 PF13456.1 ETO13518.1 - 0.11 12.2 0.2 1.1 9.0 0.2 2.5 1 1 0 1 1 1 0 Reverse transcriptase-like Lipoprotein_7 PF01540.11 ETO13518.1 - 0.24 10.4 4.5 0.045 12.8 0.4 1.6 2 0 0 2 2 2 0 Adhesin lipoprotein Ras PF00071.17 ETO13519.1 - 4e-29 101.0 0.0 1.3e-28 99.4 0.0 1.8 2 0 0 2 2 2 1 Ras family Miro PF08477.8 ETO13519.1 - 1.4e-13 51.3 0.0 4.2e-13 49.8 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO13519.1 - 5.6e-06 25.7 0.0 9.2e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETO13519.1 - 0.045 13.7 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase His_Phos_2 PF00328.17 ETO13520.1 - 6.7e-16 58.5 0.1 1.3e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 ETO13520.1 - 0.012 15.0 0.0 0.16 11.3 0.0 2.3 2 0 0 2 2 2 0 RimK-like ATP-grasp domain LigB PF02900.13 ETO13521.1 - 6.6e-20 71.2 0.0 8.5e-20 70.8 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Epimerase PF01370.16 ETO13522.1 - 4.3e-28 98.3 0.0 6e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 ETO13522.1 - 1.3e-11 43.9 0.0 7.9e-11 41.3 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 ETO13522.1 - 2e-11 43.3 0.0 2.6e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 ETO13522.1 - 6.2e-11 41.5 0.0 1.3e-10 40.4 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 ETO13522.1 - 6.3e-10 38.3 0.0 8e-09 34.7 0.0 2.5 3 0 0 3 3 3 1 Male sterility protein adh_short PF00106.20 ETO13522.1 - 3.9e-07 30.1 0.0 7e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 ETO13522.1 - 0.00015 21.7 0.0 0.00034 20.6 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 ETO13522.1 - 0.019 14.6 0.2 0.07 12.7 0.0 2.0 2 1 0 2 2 2 0 KR domain PRCC PF10253.4 ETO13523.1 - 1e-05 26.3 6.9 1e-05 26.3 4.8 4.4 1 1 1 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting Mito_fiss_reg PF05308.6 ETO13525.1 - 0.00028 20.3 3.2 0.00061 19.2 2.2 1.6 1 0 0 1 1 1 1 Mitochondrial fission regulator Tox-MPTase4 PF15640.1 ETO13525.1 - 0.057 13.0 0.2 0.099 12.2 0.2 1.3 1 0 0 1 1 1 0 Metallopeptidase toxin 4 Microtub_assoc PF07989.6 ETO13525.1 - 0.66 9.8 4.8 0.26 11.1 0.2 2.4 2 0 0 2 2 2 0 Microtubule associated DUF4200 PF13863.1 ETO13525.1 - 0.76 9.7 11.3 2.4 8.1 1.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) RasGAP_C PF03836.10 ETO13525.1 - 1.2 8.8 12.5 0.15 11.7 3.3 2.3 1 1 0 2 2 2 0 RasGAP C-terminus B56 PF01603.15 ETO13526.1 - 1.4e-30 106.2 1.8 1.4e-30 106.2 0.3 1.6 2 0 0 2 2 2 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF445 PF04286.7 ETO13526.1 - 0.1 12.1 0.1 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF830 PF05708.7 ETO13527.1 - 0.00087 19.3 0.9 0.0026 17.7 0.6 1.9 1 1 0 1 1 1 1 Orthopoxvirus protein of unknown function (DUF830) Mucin PF01456.12 ETO13527.1 - 0.42 10.3 22.0 0.79 9.4 15.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF1510 PF07423.6 ETO13527.1 - 0.64 9.3 23.7 1.1 8.5 7.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) AIF_C PF14721.1 ETO13527.1 - 5.7 7.1 12.8 3 8.0 0.9 2.5 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CPSF100_C PF13299.1 ETO13527.1 - 9 6.4 14.2 7.4 6.7 2.7 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Secretin_N_2 PF07655.8 ETO13528.1 - 0.027 14.8 14.3 0.048 14.0 9.9 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain Autophagy_N PF03986.8 ETO13528.1 - 0.068 12.9 4.8 0.51 10.1 0.1 2.8 3 0 0 3 3 3 0 Autophagocytosis associated protein (Atg3), N-terminal domain WD40 PF00400.27 ETO13528.1 - 0.092 12.6 1.5 1.3 9.0 0.3 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO13528.1 - 0.12 12.5 2.7 5.1 7.4 0.0 3.7 4 0 0 4 4 4 0 Kelch motif TMF_DNA_bd PF12329.3 ETO13529.1 - 6.6e-06 25.8 13.1 6.6e-06 25.8 9.1 11.9 8 3 5 13 13 13 2 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.4 ETO13529.1 - 0.00021 21.1 140.5 0.13 12.0 7.9 7.8 2 1 1 6 6 6 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.1 ETO13529.1 - 0.00082 17.9 30.8 0.00082 17.9 21.4 5.0 3 1 2 5 5 5 2 AAA domain DivIC PF04977.10 ETO13529.1 - 0.0021 17.5 1.1 0.0021 17.5 0.7 13.0 8 4 7 15 15 15 4 Septum formation initiator Reo_sigmaC PF04582.7 ETO13529.1 - 0.0043 16.2 39.3 0.14 11.3 0.1 6.0 2 1 3 6 6 6 4 Reovirus sigma C capsid protein LMBR1 PF04791.11 ETO13529.1 - 0.038 12.5 0.0 0.038 12.5 0.0 5.0 1 1 1 4 4 4 0 LMBR1-like membrane protein MltA PF03562.12 ETO13530.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 MltA specific insert domain APC_CDC26 PF10471.4 ETO13530.1 - 0.12 13.1 0.8 0.22 12.2 0.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 DUF2620 PF10941.3 ETO13531.1 - 0.0084 16.1 0.3 0.028 14.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function DUF2620 Ehrlichia_rpt PF09528.5 ETO13531.1 - 0.071 11.2 0.1 0.073 11.2 0.0 1.1 1 0 0 1 1 1 0 Ehrlichia tandem repeat (Ehrlichia_rpt) HALZ PF02183.13 ETO13532.1 - 0.00032 20.3 12.5 0.015 14.9 0.6 4.7 4 1 1 5 5 5 1 Homeobox associated leucine zipper Spc7 PF08317.6 ETO13532.1 - 0.00085 18.0 28.1 0.0021 16.7 11.4 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein IncA PF04156.9 ETO13532.1 - 0.001 18.7 34.5 0.019 14.5 11.7 2.2 1 1 1 2 2 2 2 IncA protein Filament PF00038.16 ETO13532.1 - 0.0041 16.6 33.4 0.18 11.2 6.0 2.1 1 1 0 2 2 2 2 Intermediate filament protein Syntaxin PF00804.20 ETO13532.1 - 0.007 16.5 2.5 0.007 16.5 1.7 3.1 1 1 1 2 2 1 1 Syntaxin Seryl_tRNA_N PF02403.17 ETO13532.1 - 0.0088 16.0 28.2 0.33 10.9 5.5 3.1 1 1 0 2 2 2 2 Seryl-tRNA synthetase N-terminal domain Mnd1 PF03962.10 ETO13532.1 - 0.017 14.8 33.2 0.13 11.8 9.9 2.2 1 1 1 2 2 2 0 Mnd1 family TPR_MLP1_2 PF07926.7 ETO13532.1 - 0.017 14.8 40.7 0.3 10.8 8.8 2.5 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein TBPIP PF07106.8 ETO13532.1 - 0.021 14.3 32.0 0.5 9.9 9.3 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tropomyosin_1 PF12718.2 ETO13532.1 - 0.03 14.1 37.9 0.55 10.0 7.5 2.3 1 1 1 2 2 2 0 Tropomyosin like GAS PF13851.1 ETO13532.1 - 0.042 13.0 36.5 0.097 11.8 14.2 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding NPV_P10 PF05531.7 ETO13532.1 - 0.048 13.9 9.2 0.82 9.9 0.1 3.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3450 PF11932.3 ETO13532.1 - 0.052 12.7 29.1 0.11 11.7 8.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) WXG100 PF06013.7 ETO13532.1 - 0.077 12.9 0.4 0.077 12.9 0.3 3.4 3 1 0 3 3 3 0 Proteins of 100 residues with WXG Lectin_N PF03954.9 ETO13532.1 - 0.14 11.5 14.9 0.12 11.7 1.1 2.9 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Tropomyosin PF00261.15 ETO13532.1 - 0.15 11.1 32.4 0.23 10.5 6.3 3.0 1 1 2 3 3 3 0 Tropomyosin Mod_r PF07200.8 ETO13532.1 - 0.26 11.2 32.6 0.38 10.6 9.1 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Hemerythrin PF01814.18 ETO13532.1 - 0.32 11.1 9.8 6.5 6.9 4.5 2.9 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain DUF3584 PF12128.3 ETO13532.1 - 0.68 7.1 29.3 1.1 6.4 20.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF948 PF06103.6 ETO13532.1 - 0.71 9.7 13.6 0.2 11.5 0.8 3.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4407 PF14362.1 ETO13532.1 - 0.86 8.5 23.2 6.4 5.6 0.8 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Nup54 PF13874.1 ETO13532.1 - 0.94 9.1 19.5 0.29 10.8 0.8 2.6 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 DUF2968 PF11180.3 ETO13532.1 - 0.97 8.7 26.7 0.85 8.9 6.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Spc24 PF08286.6 ETO13532.1 - 1 9.0 33.5 0.38 10.4 4.0 3.8 1 1 3 4 4 4 0 Spc24 subunit of Ndc80 BicD PF09730.4 ETO13532.1 - 1.2 7.3 31.4 0.031 12.6 5.5 2.1 1 1 1 2 2 2 0 Microtubule-associated protein Bicaudal-D CENP-Q PF13094.1 ETO13532.1 - 2.3 8.2 35.8 0.74 9.8 5.5 3.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Reo_sigmaC PF04582.7 ETO13532.1 - 2.7 7.0 6.8 7.6 5.6 1.7 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Pox_A11 PF05061.8 ETO13532.1 - 2.8 6.9 12.1 3.5 6.6 8.4 1.1 1 0 0 1 1 1 0 Poxvirus A11 Protein APG6 PF04111.7 ETO13532.1 - 2.9 6.8 38.0 1.1 8.2 15.9 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 Ax_dynein_light PF10211.4 ETO13532.1 - 3.4 7.4 32.9 1.5 8.6 10.8 2.2 1 1 0 2 2 2 0 Axonemal dynein light chain ADIP PF11559.3 ETO13532.1 - 3.5 7.5 37.8 0.93 9.3 7.0 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF745 PF05335.8 ETO13532.1 - 3.6 7.0 24.3 3.8 6.9 9.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) MCPsignal PF00015.16 ETO13532.1 - 4.6 6.7 13.3 2.7 7.4 0.7 2.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.7 ETO13532.1 - 7.8 6.3 15.9 3.3 7.5 2.0 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) CCDC155 PF14662.1 ETO13532.1 - 7.9 6.0 32.9 3.3 7.2 13.0 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 CENP-F_leu_zip PF10473.4 ETO13532.1 - 8.1 6.2 35.1 9.4 6.0 12.7 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Med9 PF07544.8 ETO13532.1 - 8.3 6.2 20.3 0.042 13.5 1.9 3.4 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 ING PF12998.2 ETO13532.1 - 8.8 6.6 25.7 0.065 13.5 1.1 3.1 1 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding PRKCSH PF07915.8 ETO13534.1 - 0.9 10.3 4.7 2.9 8.7 0.2 2.3 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein zf-Di19 PF05605.7 ETO13536.1 - 0.0092 16.0 0.5 0.0092 16.0 0.3 3.4 2 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 ETO13536.1 - 0.03 14.6 3.0 0.03 14.6 2.1 4.0 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_4 PF13894.1 ETO13536.1 - 0.043 14.1 1.0 0.043 14.1 0.7 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.21 ETO13536.1 - 0.38 11.1 30.2 0.088 13.1 1.3 5.3 6 0 0 6 6 6 0 Zinc finger, C2H2 type His_Phos_1 PF00300.17 ETO13537.1 - 7.7e-13 48.8 0.0 1.8e-12 47.6 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ctr PF04145.10 ETO13537.1 - 0.69 9.9 4.5 0.3 11.1 0.5 2.4 3 1 0 3 3 3 0 Ctr copper transporter family Bap31 PF05529.7 ETO13537.1 - 2.9 7.3 7.3 7 6.0 1.4 2.5 2 1 0 2 2 2 0 B-cell receptor-associated protein 31-like YMF19 PF02326.10 ETO13537.1 - 3.3 8.3 7.5 0.57 10.7 1.8 2.3 3 0 0 3 3 3 0 Plant ATP synthase F0 ATP-synt_8 PF00895.15 ETO13537.1 - 8.9 6.6 7.7 27 5.0 1.7 2.7 2 0 0 2 2 2 0 ATP synthase protein 8 FAD-oxidase_C PF02913.14 ETO13538.1 - 5.5e-42 143.7 0.0 7.4e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 ETO13538.1 - 4.1e-31 107.3 0.0 4.3e-26 91.0 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain PLDc_2 PF13091.1 ETO13539.1 - 2.4e-29 101.6 0.0 3.3e-18 65.6 0.0 2.8 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 ETO13539.1 - 1.3e-08 34.3 4.6 0.00043 19.9 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif DNA_pol3_delta PF06144.8 ETO13539.1 - 0.067 12.7 3.2 4 6.9 0.1 2.7 1 1 1 2 2 2 0 DNA polymerase III, delta subunit Cupredoxin_1 PF13473.1 ETO13540.1 - 0.12 12.2 0.1 0.24 11.3 0.0 1.6 1 1 0 1 1 1 0 Cupredoxin-like domain WD40 PF00400.27 ETO13541.1 - 2.1e-35 119.3 21.9 2.2e-08 33.6 0.6 5.8 6 1 0 6 6 6 5 WD domain, G-beta repeat F-box-like PF12937.2 ETO13542.1 - 6.8e-07 28.9 0.5 1.2e-06 28.0 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETO13542.1 - 1.3e-06 27.9 0.7 3.6e-06 26.4 0.1 2.0 2 0 0 2 2 2 1 F-box domain WD40 PF00400.27 ETO13542.1 - 8.2e-06 25.5 0.0 2.6e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 WD domain, G-beta repeat zf-RING_2 PF13639.1 ETO13543.1 - 1.2e-13 50.6 3.7 1.2e-13 50.6 2.6 1.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 ETO13543.1 - 2.6e-08 33.3 4.0 5.2e-08 32.4 2.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO13543.1 - 7.1e-08 32.3 5.1 1.4e-07 31.4 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO13543.1 - 8e-08 31.8 3.3 8e-08 31.8 2.3 1.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETO13543.1 - 1.2e-07 31.6 6.7 2.2e-07 30.9 4.4 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 ETO13543.1 - 3.6e-06 26.5 3.1 3.6e-06 26.5 2.1 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 ETO13543.1 - 1.5e-05 24.7 1.0 2.7e-05 23.9 0.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 ETO13543.1 - 0.0072 16.2 0.9 0.0072 16.2 0.6 2.6 2 1 1 3 3 3 1 FANCL C-terminal domain zf-RING_4 PF14570.1 ETO13543.1 - 0.01 15.3 3.7 0.025 14.1 2.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.6 ETO13543.1 - 0.061 13.1 2.1 0.11 12.3 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) PHD PF00628.24 ETO13543.1 - 0.36 10.5 9.2 0.073 12.7 2.9 2.3 2 1 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.1 ETO13543.1 - 0.51 10.1 11.0 0.069 12.8 1.2 2.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.6 ETO13543.1 - 4.4 7.3 9.7 0.11 12.5 2.2 1.7 2 0 0 2 2 1 0 RING-like domain RINGv PF12906.2 ETO13543.1 - 4.4 7.4 12.0 1.4 9.0 3.2 2.5 1 1 1 2 2 2 0 RING-variant domain VMA21 PF09446.5 ETO13544.1 - 6.6e-07 29.1 0.7 8.7e-07 28.7 0.5 1.2 1 0 0 1 1 1 1 VMA21-like domain Trypan_PARP PF05887.6 ETO13544.1 - 0.77 9.5 9.5 1 9.1 6.6 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ubiquitin PF00240.18 ETO13545.1 - 0.0025 17.1 0.0 0.0068 15.7 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family Brevenin PF03032.10 ETO13545.1 - 0.099 12.4 5.5 1.2 8.9 2.4 2.7 2 0 0 2 2 2 0 Brevenin/esculentin/gaegurin/rugosin family Kelch_6 PF13964.1 ETO13546.1 - 0.067 13.3 0.1 0.26 11.5 0.1 2.0 1 0 0 1 1 1 0 Kelch motif Kelch_1 PF01344.20 ETO13546.1 - 0.81 9.2 5.9 0.32 10.5 0.2 2.9 4 0 0 4 4 4 0 Kelch motif Anoctamin PF04547.7 ETO13547.1 - 2.4e-27 95.7 0.3 3.4e-27 95.2 0.2 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoctamin PF04547.7 ETO13548.1 - 1.8e-41 142.2 13.6 2e-41 142.1 9.5 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Crystall_2 PF09076.5 ETO13548.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Beta/Gamma crystallin DUF3963 PF13124.1 ETO13548.1 - 0.6 9.9 8.3 0.11 12.2 1.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3963) Anoctamin PF04547.7 ETO13549.1 - 5.8e-07 28.5 8.9 5.8e-07 28.5 6.2 1.9 2 0 0 2 2 2 1 Calcium-activated chloride channel Cnd1 PF12717.2 ETO13549.1 - 3.5e-05 23.7 1.1 5.5e-05 23.0 0.7 1.3 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Enkurin PF13864.1 ETO13549.1 - 0.051 13.7 0.1 0.16 12.2 0.1 1.8 1 0 0 1 1 1 0 Calmodulin-binding UCH PF00443.24 ETO13550.1 - 3.4e-30 105.0 0.4 1e-29 103.5 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO13550.1 - 3.2e-11 43.2 0.0 5.7e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PAT1 PF09770.4 ETO13551.1 - 0.59 8.3 29.7 0.7 8.0 20.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3597 PF12200.3 ETO13551.1 - 3.9 7.8 12.3 0.47 10.8 0.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3597) DUF2464 PF10240.4 ETO13551.1 - 4.7 6.4 8.9 6.8 5.9 6.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2464) Trypan_PARP PF05887.6 ETO13551.1 - 6.9 6.4 19.2 0.88 9.3 9.8 1.9 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) HATPase_c_3 PF13589.1 ETO13552.1 - 0.15 11.6 0.3 0.3 10.7 0.2 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FAM91_C PF14648.1 ETO13553.1 - 0.098 11.4 1.8 0.11 11.3 1.3 1.0 1 0 0 1 1 1 0 FAM91 C-terminus CobT PF06213.7 ETO13553.1 - 2.2 7.3 12.3 2.9 6.9 8.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FAM176 PF14851.1 ETO13553.1 - 3.1 7.4 5.7 4 7.0 4.0 1.3 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.9 ETO13553.1 - 4.1 5.3 9.4 4.1 5.3 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Sec62 PF03839.11 ETO13553.1 - 4.9 6.4 11.8 5.3 6.3 8.2 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 NPR3 PF03666.8 ETO13553.1 - 7.2 5.0 9.4 7.3 5.0 6.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Cupin_8 PF13621.1 ETO13555.1 - 1.3e-21 77.3 3.2 1.9e-21 76.7 2.2 1.3 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 ETO13555.1 - 0.0069 16.6 2.1 0.39 10.9 0.1 2.6 2 0 0 2 2 2 2 JmjC domain, hydroxylase RPAP3_C PF13877.1 ETO13557.1 - 0.043 13.7 0.4 6.9 6.7 0.1 2.4 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 GatB_Yqey PF02637.13 ETO13557.1 - 0.14 11.8 1.3 2.5 7.8 0.1 2.5 1 1 1 2 2 2 0 GatB domain TACC PF05010.9 ETO13557.1 - 1.2 8.8 9.1 4 7.1 6.1 1.9 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) Gti1_Pac2 PF09729.4 ETO13558.1 - 0.026 14.3 2.7 0.029 14.2 1.9 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Apc15p PF05841.6 ETO13558.1 - 0.026 15.2 0.9 0.034 14.8 0.6 1.2 1 0 0 1 1 1 0 Apc15p protein GreA_GreB_N PF03449.10 ETO13558.1 - 3.6 7.7 11.5 1.7 8.7 0.3 2.6 2 1 1 3 3 3 0 Transcription elongation factor, N-terminal HECT PF00632.20 ETO13559.1 - 7.6e-94 314.4 0.3 1.7e-93 313.3 0.2 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) eIF3_subunit PF08597.5 ETO13559.1 - 0.016 14.7 0.7 0.016 14.7 0.5 1.5 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Orbi_VP6 PF01516.11 ETO13560.1 - 3.1 6.7 11.8 4.3 6.3 8.2 1.1 1 0 0 1 1 1 0 Orbivirus helicase VP6 GCD14 PF08704.5 ETO13564.1 - 1.8 7.9 7.7 3.4 7.1 5.3 1.6 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Utp14 PF04615.8 ETO13564.1 - 2.9 5.9 31.0 3.6 5.6 21.5 1.0 1 0 0 1 1 1 0 Utp14 protein Sugar_tr PF00083.19 ETO13565.1 - 0.1 11.1 1.2 0.14 10.7 0.9 1.2 1 0 0 1 1 1 0 Sugar (and other) transporter VWA_N PF08399.6 ETO13565.1 - 0.62 10.6 3.9 0.77 10.3 2.2 1.6 1 1 0 1 1 1 0 VWA N-terminal Hom_end_hint PF05203.11 ETO13565.1 - 2.1 8.0 8.0 2.6 7.7 5.5 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint Lipase PF00151.14 ETO13565.1 - 5.7 6.0 7.6 6.3 5.9 5.3 1.1 1 0 0 1 1 1 0 Lipase DUF2962 PF11176.3 ETO13565.1 - 7.7 6.0 21.4 1.6 8.2 5.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2962) TPR_2 PF07719.12 ETO13566.1 - 1e-08 34.4 9.6 0.008 16.0 0.2 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO13566.1 - 6.1e-08 32.1 13.7 0.0032 17.0 1.4 4.3 2 2 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 ETO13566.1 - 1.5e-06 27.5 7.6 0.049 13.2 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO13566.1 - 2e-06 27.6 19.9 0.0096 15.8 1.2 4.8 4 1 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO13566.1 - 2e-06 27.1 15.8 0.055 13.2 1.1 4.9 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO13566.1 - 2.8e-05 24.3 9.4 2 8.8 0.9 4.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO13566.1 - 0.0016 18.8 3.7 2.1 9.2 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO13566.1 - 0.0023 17.5 1.9 3.3 7.7 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETO13566.1 - 0.0036 17.1 0.4 3.2 7.8 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF4398 PF14346.1 ETO13566.1 - 0.0057 16.6 11.5 0.085 12.9 0.0 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF4398) DUF3560 PF12083.3 ETO13566.1 - 0.12 12.4 4.9 0.46 10.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3560) TPR_17 PF13431.1 ETO13566.1 - 0.18 12.0 3.9 6.3 7.2 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 ETO13567.1 - 1.1e-13 50.5 9.7 5.2e-05 22.8 0.1 4.2 3 1 1 4 4 4 4 TPR repeat TPR_2 PF07719.12 ETO13567.1 - 8.9e-12 43.9 9.1 0.023 14.6 0.0 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 ETO13567.1 - 2.3e-11 43.4 4.2 0.00056 19.8 0.2 4.5 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO13567.1 - 5e-08 32.5 3.5 0.0016 18.4 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO13567.1 - 1.4e-07 31.6 0.1 0.0014 18.9 0.0 3.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO13567.1 - 4.5e-07 29.2 6.6 0.071 12.7 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO13567.1 - 1.9e-05 24.1 10.9 0.14 12.0 0.3 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO13567.1 - 2.1e-05 24.7 0.0 5.1 7.9 0.0 4.0 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO13567.1 - 6e-05 23.6 0.1 0.95 10.2 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO13567.1 - 0.022 14.6 0.0 15 5.7 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA PF00004.24 ETO13568.1 - 1.5e-41 141.6 0.0 2.3e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETO13568.1 - 1.4e-07 31.6 0.1 1.4e-06 28.4 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 ETO13568.1 - 3.7e-07 30.2 0.0 2.2e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 ETO13568.1 - 1.2e-05 25.4 0.1 0.00018 21.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 ETO13568.1 - 2.2e-05 24.1 0.0 0.00011 21.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 ETO13568.1 - 3.2e-05 23.0 0.0 6.8e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 ETO13568.1 - 3.3e-05 23.3 0.0 0.00014 21.3 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.1 ETO13568.1 - 8e-05 23.4 0.1 0.00038 21.2 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 ETO13568.1 - 0.00014 21.7 0.0 0.00033 20.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 ETO13568.1 - 0.00017 21.4 0.0 0.00049 19.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 ETO13568.1 - 0.00029 20.2 0.9 0.2 11.0 0.1 2.6 1 1 2 3 3 3 2 AAA domain TIP49 PF06068.8 ETO13568.1 - 0.00059 18.6 0.0 0.00081 18.2 0.0 1.1 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 ETO13568.1 - 0.00084 19.4 0.0 0.0022 18.1 0.0 1.9 1 1 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.16 ETO13568.1 - 0.0021 17.2 0.0 0.0039 16.3 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.7 ETO13568.1 - 0.003 17.2 0.0 0.069 12.7 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.7 ETO13568.1 - 0.0034 16.4 0.0 0.0059 15.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin ABC_tran PF00005.22 ETO13568.1 - 0.004 17.4 0.0 0.006 16.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter Arch_ATPase PF01637.13 ETO13568.1 - 0.0042 16.8 0.0 0.12 11.9 0.0 2.2 1 1 1 2 2 2 1 Archaeal ATPase Sigma54_activ_2 PF14532.1 ETO13568.1 - 0.0052 16.8 0.0 0.02 14.9 0.0 2.0 1 1 1 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.1 ETO13568.1 - 0.0053 16.7 0.0 0.012 15.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETO13568.1 - 0.0068 16.1 0.3 0.017 14.8 0.2 1.7 1 1 0 1 1 1 1 Part of AAA domain AAA_24 PF13479.1 ETO13568.1 - 0.011 15.3 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 ETO13568.1 - 0.017 14.5 0.0 0.035 13.5 0.0 1.6 2 0 0 2 2 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 ETO13568.1 - 0.019 13.8 0.0 0.035 12.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF815 PF05673.8 ETO13568.1 - 0.023 13.6 0.0 0.037 12.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 ETO13568.1 - 0.023 14.9 0.0 0.053 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 ETO13568.1 - 0.039 13.1 0.1 0.081 12.1 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein Rad17 PF03215.10 ETO13568.1 - 0.058 12.0 0.1 0.27 9.8 0.0 1.8 1 1 1 2 2 2 0 Rad17 cell cycle checkpoint protein KaiC PF06745.8 ETO13568.1 - 0.087 11.9 0.1 0.36 9.8 0.0 2.0 2 1 1 3 3 3 0 KaiC AAA_3 PF07726.6 ETO13568.1 - 0.098 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 ETO13568.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Abhydrolase_9 PF10081.4 ETO13568.1 - 0.11 11.1 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family BCAS3 PF12490.3 ETO13569.1 - 4.5e-06 26.1 0.7 4.5e-06 26.1 0.5 1.9 2 0 0 2 2 2 1 Breast carcinoma amplified sequence 3 Hydrolase_like2 PF13246.1 ETO13571.1 - 3.4e-17 62.1 0.0 4e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit TPR_17 PF13431.1 ETO13572.1 - 9.8e-05 22.2 5.0 0.017 15.3 0.4 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO13572.1 - 0.00027 20.5 5.4 0.026 14.1 0.5 3.1 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 ETO13572.1 - 0.0033 17.2 3.0 0.9 9.6 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO13572.1 - 0.037 13.9 1.0 3.1 7.7 0.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETO13572.1 - 0.068 12.8 7.2 5.8 6.6 0.1 4.4 3 1 0 3 3 3 0 Tetratricopeptide repeat EF-hand_5 PF13202.1 ETO13573.1 - 9.5e-05 21.5 0.5 0.00026 20.2 0.4 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 ETO13573.1 - 0.00083 19.0 0.2 0.0031 17.2 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 ETO13573.1 - 0.00083 19.4 0.3 0.00083 19.4 0.2 1.9 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO13573.1 - 0.0009 18.3 0.6 0.0009 18.3 0.4 2.1 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 ETO13573.1 - 0.049 13.2 1.5 0.09 12.4 0.2 2.1 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_7 PF13499.1 ETO13574.1 - 0.028 14.5 0.4 6.6 6.9 0.0 3.3 3 2 0 3 3 3 0 EF-hand domain pair WD40 PF00400.27 ETO13575.1 - 5.3e-08 32.4 0.2 5.3e-08 32.4 0.2 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat Methyltransf_12 PF08242.7 ETO13575.1 - 0.1 13.1 0.7 0.34 11.3 0.0 2.3 3 0 0 3 3 3 0 Methyltransferase domain DUF2956 PF11169.3 ETO13575.1 - 6 6.8 15.8 0.24 11.3 0.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2956) tRNA_m1G_MT PF01746.16 ETO13578.1 - 4.6e-11 42.6 0.0 6.2e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase NGP1NT PF08153.7 ETO13579.1 - 2.2e-42 144.0 2.6 4.9e-42 142.9 1.8 1.6 1 0 0 1 1 1 1 NGP1NT (NUC091) domain DUF359 PF04019.7 ETO13579.1 - 0.063 12.6 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF359) MMR_HSR1 PF01926.18 ETO13580.1 - 9.6e-15 54.5 0.0 1.7e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETO13580.1 - 0.00017 20.8 0.0 0.00031 20.0 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 ETO13580.1 - 0.0031 17.3 0.2 0.0031 17.3 0.1 3.0 2 2 1 3 3 3 1 Dynamin family DUF258 PF03193.11 ETO13580.1 - 0.022 13.9 0.0 0.041 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 ETO13580.1 - 0.049 13.9 0.2 0.37 11.0 0.0 2.4 2 1 0 2 2 2 0 ABC transporter Miro PF08477.8 ETO13580.1 - 0.056 13.9 0.4 0.15 12.5 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein ArgK PF03308.11 ETO13580.1 - 0.058 12.1 0.0 0.09 11.5 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA_16 PF13191.1 ETO13580.1 - 0.094 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.9 ETO13580.1 - 0.12 12.0 0.1 0.33 10.6 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 ETO13580.1 - 0.94 10.3 7.0 1.8e+02 2.9 4.8 3.2 1 1 0 1 1 1 0 AAA domain Ank_2 PF12796.2 ETO13581.1 - 1.9e-08 34.5 2.2 0.0006 20.1 0.9 3.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETO13581.1 - 1.6e-07 30.7 1.4 0.0013 18.4 0.0 5.1 6 1 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.1 ETO13581.1 - 9.3e-07 29.2 5.6 0.049 14.1 0.2 4.1 3 2 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO13581.1 - 7.9e-06 25.6 2.9 0.086 13.1 0.0 5.7 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.1 ETO13581.1 - 1.5e-05 25.0 0.7 0.041 14.1 0.0 3.2 3 1 0 3 3 3 2 Ankyrin repeats (many copies) DUF4508 PF14969.1 ETO13581.1 - 0.0029 17.5 0.1 0.0065 16.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4508) XRCC4 PF06632.7 ETO13582.1 - 0.81 8.4 8.7 2.3 6.9 6.0 1.7 1 1 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Uds1 PF15456.1 ETO13582.1 - 2.1 8.3 6.5 14 5.7 0.3 2.2 2 0 0 2 2 2 0 Up-regulated During Septation zf-CCCH PF00642.19 ETO13583.1 - 2.6e-06 26.9 13.2 8e-05 22.2 1.6 4.5 5 0 0 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF848 PF05852.6 ETO13583.1 - 0.0095 15.7 3.1 0.018 14.8 2.1 1.5 1 0 0 1 1 1 1 Gammaherpesvirus protein of unknown function (DUF848) Fe_dep_repr_C PF02742.10 ETO13583.1 - 0.02 14.5 0.1 0.07 12.8 0.1 1.9 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain TPR_11 PF13414.1 ETO13584.1 - 3.4e-16 58.6 3.2 2.8e-05 23.6 0.1 3.7 3 0 0 3 3 3 3 TPR repeat TPR_2 PF07719.12 ETO13584.1 - 2.8e-09 36.1 5.4 0.018 14.8 0.4 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO13584.1 - 3.6e-09 36.4 3.7 0.011 15.6 0.0 4.3 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO13584.1 - 3e-08 32.8 10.4 0.012 15.3 0.2 5.6 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO13584.1 - 1.8e-07 30.7 0.2 0.097 12.9 0.1 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO13584.1 - 4.2e-07 29.3 12.8 0.0022 17.5 0.7 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO13584.1 - 0.00015 22.0 0.0 4.7 8.1 0.0 4.2 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO13584.1 - 0.0013 19.0 1.0 3.1 8.2 0.0 3.9 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO13584.1 - 0.0015 19.1 1.0 2.2 9.0 0.1 2.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 ETO13584.1 - 0.0018 18.0 0.1 0.061 13.1 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO13584.1 - 0.0037 16.9 0.9 0.68 9.8 0.2 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO13584.1 - 0.072 13.5 0.0 45 4.8 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4475 PF14753.1 ETO13585.1 - 0.0032 16.9 0.6 0.004 16.6 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4475) DUF713 PF05218.9 ETO13585.1 - 0.017 14.8 0.4 0.027 14.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF713) Iron_traffic PF04362.9 ETO13585.1 - 0.087 12.2 0.2 0.46 9.9 0.0 2.0 2 1 0 2 2 2 0 Bacterial Fe(2+) trafficking MBT PF02820.13 ETO13585.1 - 0.087 12.7 0.2 11 5.9 0.0 2.3 1 1 1 2 2 2 0 mbt repeat Tudor-knot PF11717.3 ETO13585.1 - 0.84 9.3 5.6 0.74 9.5 2.1 2.3 1 1 1 2 2 2 0 RNA binding activity-knot of a chromodomain Vsr PF03852.10 ETO13586.1 - 0.028 14.0 0.4 0.063 12.8 0.1 1.8 2 0 0 2 2 2 0 DNA mismatch endonuclease Vsr Viral_Beta_CD PF04530.7 ETO13586.1 - 0.13 12.4 0.3 0.25 11.5 0.2 1.5 1 0 0 1 1 1 0 Viral Beta C/D like family PhyH PF05721.8 ETO13587.1 - 0.0005 20.1 0.0 0.0035 17.4 0.0 2.2 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 ETO13587.1 - 0.0022 16.5 0.0 0.012 14.1 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1479) CBF PF03914.12 ETO13587.1 - 0.16 11.4 1.5 1 8.7 0.0 2.1 2 0 0 2 2 2 0 CBF/Mak21 family Cloacin_immun PF03513.9 ETO13588.1 - 0.19 11.7 3.6 0.92 9.6 0.3 2.1 1 1 1 2 2 2 0 Cloacin immunity protein Fmp27 PF10344.4 ETO13589.1 - 0.002 15.9 0.5 0.0027 15.4 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 CDC45 PF02724.9 ETO13589.1 - 0.074 11.0 6.0 0.084 10.8 4.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Pox_RNA_Pol_19 PF05320.7 ETO13589.1 - 0.14 11.9 6.5 0.24 11.1 4.5 1.4 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Ycf1 PF05758.7 ETO13589.1 - 0.17 9.5 5.6 0.19 9.4 3.9 1.0 1 0 0 1 1 1 0 Ycf1 IFT57 PF10498.4 ETO13589.1 - 0.22 10.2 6.0 0.33 9.6 4.1 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Daxx PF03344.10 ETO13589.1 - 0.26 9.7 11.4 0.35 9.2 7.9 1.2 1 0 0 1 1 1 0 Daxx Family eIF-3c_N PF05470.7 ETO13589.1 - 0.33 9.0 4.1 0.32 9.0 2.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus BSP_II PF05432.6 ETO13589.1 - 0.45 9.7 20.1 0.79 8.9 13.9 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) RRN3 PF05327.6 ETO13589.1 - 0.85 7.6 3.2 0.81 7.7 2.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Vfa1 PF08432.5 ETO13589.1 - 0.94 9.4 10.6 0.42 10.6 5.3 1.7 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Nop14 PF04147.7 ETO13589.1 - 1 7.2 15.9 1.7 6.4 11.0 1.3 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.5 ETO13589.1 - 1.2 9.3 10.4 2.4 8.4 7.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DDHD PF02862.12 ETO13589.1 - 2.3 7.9 9.3 0.088 12.5 2.5 1.4 2 0 0 2 2 2 0 DDHD domain TRAP_alpha PF03896.11 ETO13589.1 - 2.6 6.9 12.0 1.6 7.6 6.9 1.6 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Nucleoplasmin PF03066.10 ETO13589.1 - 4.3 6.8 14.7 8.4 5.9 10.2 1.4 1 0 0 1 1 1 0 Nucleoplasmin FAM176 PF14851.1 ETO13589.1 - 4.3 6.9 10.2 3.5 7.2 5.9 1.6 2 0 0 2 2 2 0 FAM176 family Tim54 PF11711.3 ETO13589.1 - 4.5 5.7 9.1 6 5.3 6.3 1.4 1 1 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 GOLD_2 PF13897.1 ETO13589.1 - 4.8 7.4 6.5 10 6.3 3.9 1.8 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Paf1 PF03985.8 ETO13589.1 - 5.4 5.6 14.9 9.2 4.8 10.3 1.4 1 0 0 1 1 1 0 Paf1 Rhabdo_ncap PF00945.13 ETO13589.1 - 7.4 5.0 6.7 10 4.5 4.7 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Tom37_C PF11801.3 ETO13589.1 - 8.7 6.1 6.8 20 4.9 3.1 2.0 2 0 0 2 2 2 0 Tom37 C-terminal domain WBS_methylT PF12589.3 ETO13589.1 - 10 6.7 13.0 1.1 9.7 5.1 1.9 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome Ank_2 PF12796.2 ETO13590.1 - 0.00031 21.0 0.2 0.001 19.3 0.2 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) SDA1 PF05285.7 ETO13590.1 - 0.002 17.4 39.6 0.068 12.4 10.4 2.2 2 0 0 2 2 2 2 SDA1 Ank PF00023.25 ETO13590.1 - 0.019 14.7 0.1 0.16 11.8 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.1 ETO13590.1 - 0.059 13.6 0.7 0.78 10.1 0.1 2.8 2 0 0 2 2 2 0 Ankyrin repeat Nop14 PF04147.7 ETO13590.1 - 0.52 8.1 44.8 0.29 8.9 11.6 2.4 2 0 0 2 2 2 0 Nop14-like family Astro_capsid PF03115.9 ETO13590.1 - 7.3 4.7 18.6 1.2 7.2 4.6 2.2 2 0 0 2 2 2 0 Astrovirus capsid protein precursor CAF-1_p150 PF11600.3 ETO13590.1 - 9.4 5.5 30.8 1.1 8.5 15.8 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DisA_N PF02457.11 ETO13591.1 - 8.1e-16 57.2 0.0 1.9e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 DisA bacterial checkpoint controller nucleotide-binding CENP-B_dimeris PF09026.5 ETO13591.1 - 0.028 14.6 12.9 0.15 12.3 9.0 2.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Med15 PF09606.5 ETO13593.1 - 0.082 11.1 53.7 0.087 11.0 37.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RNA_pol_3_Rpc31 PF11705.3 ETO13593.1 - 0.84 9.5 22.3 0.031 14.2 6.2 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2052 PF09747.4 ETO13593.1 - 1.4 8.7 29.1 1.3 8.9 4.6 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Ribosomal_60s PF00428.14 ETO13593.1 - 6.1 7.3 12.2 16 5.9 8.4 1.7 1 1 0 1 1 1 0 60s Acidic ribosomal protein SDA1 PF05285.7 ETO13595.1 - 6.2e-47 160.4 19.9 6.2e-47 160.4 13.8 2.2 2 0 0 2 2 2 1 SDA1 Acetyltransf_6 PF13480.1 ETO13595.1 - 0.00095 19.1 0.7 0.0029 17.5 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain zf-RING_2 PF13639.1 ETO13596.1 - 2.8e-14 52.6 4.7 2.8e-14 52.6 3.3 2.0 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 ETO13596.1 - 1.5e-08 34.6 3.8 4.2e-08 33.1 2.6 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 ETO13596.1 - 8.1e-08 32.1 5.3 2e-07 30.8 3.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO13596.1 - 1.2e-07 31.3 3.1 2.6e-07 30.2 2.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO13596.1 - 1.3e-06 27.9 4.2 3.4e-06 26.6 2.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO13596.1 - 1.3e-05 24.8 3.5 3.3e-05 23.5 2.4 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 ETO13596.1 - 0.0027 17.3 2.6 0.0028 17.3 0.5 2.2 2 1 0 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 ETO13596.1 - 0.0037 17.0 4.1 0.025 14.4 2.9 2.3 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.1 ETO13596.1 - 0.017 14.8 4.0 0.038 13.7 0.6 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.3 ETO13596.1 - 0.037 13.9 5.1 0.37 10.7 3.5 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain DUF3039 PF11238.3 ETO13596.1 - 0.037 13.4 0.9 0.083 12.3 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) zf-Nse PF11789.3 ETO13596.1 - 0.13 11.8 2.0 0.36 10.3 1.4 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 ETO13596.1 - 0.98 9.3 3.9 3 7.7 2.7 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 ETO13596.1 - 3.2 7.4 9.5 0.099 12.2 2.1 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.2 ETO13596.1 - 9 6.2 7.9 1.1 9.0 1.6 2.4 2 1 0 2 2 2 0 Double zinc ribbon ECH_C PF13766.1 ETO13597.1 - 0.00029 20.9 0.0 0.0015 18.6 0.0 2.0 1 1 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region Exo_endo_phos PF03372.18 ETO13598.1 - 4.3e-06 26.8 0.0 7.3e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RGS PF00615.14 ETO13599.1 - 5e-12 45.9 3.0 9.3e-12 45.0 2.1 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain GAGE PF05831.6 ETO13599.1 - 0.32 11.1 6.3 0.52 10.4 4.4 1.3 1 0 0 1 1 1 0 GAGE protein Chibby PF14645.1 ETO13600.1 - 0.018 14.9 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 Chibby family EGF_2 PF07974.8 ETO13601.1 - 3.4e-05 23.9 4.1 6.9e-05 22.9 2.8 1.5 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.2 ETO13601.1 - 0.0017 18.3 1.1 0.0043 17.0 0.7 1.8 1 0 0 1 1 1 1 Human growth factor-like EGF Peptidase_M56 PF05569.6 ETO13601.1 - 0.011 14.7 0.0 0.016 14.2 0.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 EGF PF00008.22 ETO13601.1 - 0.013 15.4 1.6 0.028 14.3 1.1 1.6 1 0 0 1 1 1 0 EGF-like domain MARVEL PF01284.18 ETO13601.1 - 0.02 14.7 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 Membrane-associating domain CD34_antigen PF06365.7 ETO13601.1 - 0.024 14.2 0.0 0.059 13.0 0.0 1.6 2 0 0 2 2 2 0 CD34/Podocalyxin family LRR19-TM PF15176.1 ETO13601.1 - 0.035 13.7 0.0 0.071 12.8 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Laminin_EGF PF00053.19 ETO13601.1 - 0.042 13.7 1.6 0.091 12.7 1.1 1.6 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) DUF3844 PF12955.2 ETO13601.1 - 0.061 13.4 0.2 0.12 12.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) DUF3290 PF11694.3 ETO13601.1 - 0.071 12.8 1.2 0.18 11.5 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Leu_zip PF15294.1 ETO13602.1 - 0.0042 16.2 0.3 0.005 15.9 0.2 1.2 1 0 0 1 1 1 1 Leucine zipper FliD_C PF07195.7 ETO13602.1 - 0.047 12.9 2.0 0.052 12.8 1.4 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus SPACA7 PF15307.1 ETO13602.1 - 0.093 12.8 0.5 0.13 12.4 0.3 1.3 1 0 0 1 1 1 0 Sperm acrosome-associated protein 7 Pkinase PF00069.20 ETO13603.1 - 4.5e-33 114.4 8.3 2.3e-32 112.1 5.7 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO13603.1 - 5e-13 48.7 5.1 1e-12 47.7 0.1 3.0 1 1 1 3 3 3 1 Protein tyrosine kinase RIO1 PF01163.17 ETO13603.1 - 0.29 10.4 5.2 0.17 11.1 0.6 2.8 3 1 0 3 3 3 0 RIO1 family DNA_repr_REX1B PF14966.1 ETO13604.1 - 0.2 12.0 2.5 0.38 11.1 0.0 2.6 3 0 0 3 3 3 0 DNA repair REX1-B STN1_2 PF09170.5 ETO13604.1 - 0.7 9.6 4.3 1.7 8.4 0.2 3.0 3 0 0 3 3 3 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Prenyltrans PF00432.16 ETO13606.1 - 8e-34 114.8 8.4 4.8e-12 45.2 0.0 4.3 4 0 0 4 4 4 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 ETO13606.1 - 4.6e-14 52.7 0.0 4.1e-06 27.1 0.0 2.7 1 1 2 3 3 3 3 Prenyltransferase-like HEAT_PBS PF03130.11 ETO13606.1 - 0.054 13.9 0.0 0.19 12.3 0.0 1.9 1 0 0 1 1 1 0 PBS lyase HEAT-like repeat Prenyltrans_1 PF13243.1 ETO13606.1 - 0.094 12.7 0.0 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 Prenyltransferase-like Anoctamin PF04547.7 ETO13607.1 - 0.017 13.7 0.8 0.026 13.2 0.5 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel Claudin_2 PF13903.1 ETO13607.1 - 0.066 12.9 11.2 0.4 10.3 7.6 2.2 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF1365 PF07103.6 ETO13607.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1365) AAA_16 PF13191.1 ETO13608.1 - 0.0019 18.2 0.0 0.0047 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain PH PF00169.24 ETO13608.1 - 0.03 14.4 0.0 0.11 12.6 0.0 2.0 1 0 0 1 1 1 0 PH domain Peptidase_S10 PF00450.17 ETO13609.1 - 2.5e-25 89.5 0.0 3e-25 89.2 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase IBB PF01749.15 ETO13610.1 - 8.5e-08 32.2 12.4 1.1e-07 31.8 8.6 1.1 1 0 0 1 1 1 1 Importin beta binding domain UPF0561 PF10573.4 ETO13610.1 - 0.079 12.8 5.1 0.093 12.5 3.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 Nop25 PF09805.4 ETO13610.1 - 0.9 9.6 15.4 1 9.4 10.6 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) RXT2_N PF08595.6 ETO13610.1 - 3 7.6 11.4 3 7.6 7.4 1.4 1 1 0 1 1 1 0 RXT2-like, N-terminal GEMIN8 PF15348.1 ETO13610.1 - 3.6 7.5 11.6 4.2 7.3 8.0 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Arm PF00514.18 ETO13611.1 - 8e-25 85.7 4.2 1e-09 37.8 0.0 4.6 4 1 0 4 4 4 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 ETO13611.1 - 3e-08 33.8 1.7 9.7e-05 22.5 0.1 2.0 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 ETO13611.1 - 8.6e-07 29.2 1.4 5.3e-06 26.7 0.1 2.7 3 1 1 4 4 4 1 HEAT-like repeat RICTOR_V PF14668.1 ETO13611.1 - 0.011 15.6 0.2 0.25 11.3 0.1 2.4 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.11 ETO13611.1 - 0.017 15.5 0.4 6.3 7.5 0.0 2.8 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat PEP-utilizers PF00391.18 ETO13611.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, mobile domain DUF2654 PF10849.3 ETO13611.1 - 0.14 11.9 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2654) UDPG_MGDP_dh PF00984.14 ETO13613.1 - 0.011 15.9 0.0 0.017 15.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain YWFCY PF14293.1 ETO13613.1 - 0.074 12.8 2.4 0.25 11.2 1.0 2.2 2 0 0 2 2 2 0 YWFCY protein HXXSHH PF07586.6 ETO13614.1 - 0.003 16.5 0.1 0.076 11.9 0.2 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1552) Nairovirus_M PF07948.6 ETO13614.1 - 0.095 10.8 1.6 0.13 10.3 1.1 1.1 1 0 0 1 1 1 0 Nairovirus M polyprotein-like Beach PF02138.13 ETO13615.1 - 1.6e-72 244.1 2.2 1.6e-72 244.1 1.5 2.5 2 1 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.1 ETO13615.1 - 1.6e-17 63.2 0.2 8.7e-13 48.0 0.2 3.9 5 0 0 5 5 5 2 PH domain associated with Beige/BEACH Secretin_N_2 PF07655.8 ETO13615.1 - 0.92 9.9 29.6 1.1 9.7 7.0 2.6 2 0 0 2 2 2 0 Secretin N-terminal domain Methyltransf_12 PF08242.7 ETO13615.1 - 2.2 8.8 7.2 2.2 8.8 0.2 2.6 2 0 0 2 2 2 0 Methyltransferase domain Beach PF02138.13 ETO13616.1 - 7.7e-27 94.4 0.0 1.3e-26 93.6 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 ETO13616.1 - 1.9e-08 33.8 5.6 6.3e-05 22.6 0.0 4.8 5 1 1 6 6 6 2 WD domain, G-beta repeat Cytochrome_CBB3 PF13442.1 ETO13618.1 - 0.27 11.3 1.2 0.4 10.8 0.3 1.7 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III PIG-U PF06728.8 ETO13618.1 - 0.68 8.7 13.0 0.021 13.6 3.8 2.0 2 1 1 3 3 3 0 GPI transamidase subunit PIG-U DUF4079 PF13301.1 ETO13618.1 - 1.1 9.2 5.3 0.29 11.1 1.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) TMEM37 PF15108.1 ETO13618.1 - 2.1 8.0 11.4 0.19 11.4 0.6 2.5 2 1 0 2 2 2 0 Voltage-dependent calcium channel gamma-like subunit protein family Radical_SAM PF04055.16 ETO13620.1 - 3.1e-09 37.2 0.0 9e-09 35.7 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Ivy PF08816.6 ETO13620.1 - 0.019 14.9 0.1 0.037 14.0 0.1 1.4 1 0 0 1 1 1 0 Inhibitor of vertebrate lysozyme (Ivy) Nop14 PF04147.7 ETO13620.1 - 0.11 10.3 0.3 0.17 9.8 0.2 1.1 1 0 0 1 1 1 0 Nop14-like family WD40 PF00400.27 ETO13621.1 - 2e-68 224.0 15.8 2.6e-12 46.0 0.0 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat Kelch_4 PF13418.1 ETO13621.1 - 1.9e-06 27.5 1.8 0.23 11.2 0.0 5.0 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO13621.1 - 1.9e-06 27.8 5.0 0.026 14.6 0.0 4.1 3 0 0 3 3 3 2 Kelch motif Cytochrom_D1 PF02239.11 ETO13621.1 - 5.3e-06 24.9 9.1 0.07 11.4 0.3 4.3 2 1 3 5 5 5 4 Cytochrome D1 heme domain Kelch_2 PF07646.10 ETO13621.1 - 1.3e-05 24.7 6.6 0.0063 16.2 0.1 4.3 3 1 0 3 3 3 2 Kelch motif Nup160 PF11715.3 ETO13621.1 - 1.9e-05 23.0 7.7 0.11 10.6 0.1 3.9 2 2 2 4 4 4 3 Nucleoporin Nup120/160 Kelch_1 PF01344.20 ETO13621.1 - 0.001 18.5 2.6 0.037 13.5 0.2 3.6 3 0 0 3 3 3 1 Kelch motif PD40 PF07676.7 ETO13621.1 - 0.0067 16.0 4.3 4.4 7.0 0.0 4.9 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Kelch_3 PF13415.1 ETO13621.1 - 0.025 14.7 1.6 0.88 9.8 0.0 3.7 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO13621.1 - 0.3 11.0 9.0 8.9 6.3 0.0 4.4 4 0 0 4 4 4 0 Kelch motif Daxx PF03344.10 ETO13623.1 - 0.038 12.4 34.6 0.044 12.2 24.0 1.1 1 0 0 1 1 1 0 Daxx Family PI3K_1B_p101 PF10486.4 ETO13623.1 - 2.2 5.7 12.2 2.7 5.4 8.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Nop14 PF04147.7 ETO13623.1 - 3 5.6 33.6 3.8 5.3 23.3 1.2 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.2 ETO13623.1 - 3.9 5.0 18.3 4.1 4.9 12.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LMBR1 PF04791.11 ETO13623.1 - 9.3 4.6 8.6 13 4.1 6.0 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein PilJ PF13675.1 ETO13624.1 - 0.0074 16.5 2.0 0.016 15.5 1.4 1.6 1 0 0 1 1 1 1 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4335 PF14233.1 ETO13624.1 - 0.13 11.7 3.2 0.12 11.7 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4335) EMP24_GP25L PF01105.19 ETO13624.1 - 0.21 11.2 5.3 0.05 13.3 1.0 1.9 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD CEP19 PF14933.1 ETO13624.1 - 2 8.7 6.7 14 5.9 4.6 2.3 1 1 0 1 1 1 0 CEP19-like protein DUF972 PF06156.8 ETO13624.1 - 7.7 6.9 8.4 4.8 7.5 0.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Clathrin PF00637.15 ETO13625.1 - 8.6e-06 25.4 10.6 5.8e-05 22.7 1.0 2.8 3 0 0 3 3 3 2 Region in Clathrin and VPS TPR_2 PF07719.12 ETO13626.1 - 0.0019 17.9 0.2 0.06 13.2 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Nic96 PF04097.9 ETO13626.1 - 0.0022 16.2 0.1 0.0027 15.9 0.0 1.0 1 0 0 1 1 1 1 Nup93/Nic96 TPR_19 PF14559.1 ETO13626.1 - 0.0058 16.9 0.0 3.8 7.9 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat Sec3_C PF09763.4 ETO13626.1 - 0.011 13.9 0.6 0.013 13.6 0.4 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 VAD1-2 PF15310.1 ETO13626.1 - 0.036 13.7 4.2 0.046 13.3 2.9 1.1 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling TPR_11 PF13414.1 ETO13626.1 - 0.06 12.9 0.0 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 TPR repeat TPR_12 PF13424.1 ETO13626.1 - 0.11 12.4 0.0 0.33 10.8 0.0 1.8 1 1 1 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 ETO13626.1 - 0.13 12.1 0.0 0.39 10.6 0.0 1.7 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain SR-25 PF10500.4 ETO13626.1 - 0.46 9.9 13.6 0.63 9.4 9.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SRP54 PF00448.17 ETO13628.1 - 5.2e-74 247.9 0.2 8.9e-74 247.1 0.2 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 ETO13628.1 - 8.2e-22 77.4 8.1 3e-21 75.6 0.4 3.0 2 0 0 2 2 2 1 Signal peptide binding domain SRP54_N PF02881.14 ETO13628.1 - 7.2e-10 38.8 4.2 7.2e-10 38.8 2.9 2.4 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain CbiA PF01656.18 ETO13628.1 - 1.1e-05 25.0 1.1 9.3e-05 21.9 0.0 2.9 3 1 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 ETO13628.1 - 1.7e-05 25.6 0.0 5.5e-05 23.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 ETO13628.1 - 6.6e-05 22.6 0.8 0.00025 20.7 0.0 2.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 ETO13628.1 - 0.00021 20.2 0.0 0.00053 18.8 0.0 1.7 1 0 0 1 1 1 1 ArgK protein AAA_33 PF13671.1 ETO13628.1 - 0.00037 20.3 0.0 0.00095 19.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETO13628.1 - 0.0049 17.1 1.2 0.018 15.3 0.0 2.7 3 1 0 3 3 3 1 AAA domain AAA_10 PF12846.2 ETO13628.1 - 0.0061 16.0 0.1 0.0061 16.0 0.0 1.5 2 0 0 2 2 2 1 AAA-like domain AAA_16 PF13191.1 ETO13628.1 - 0.0068 16.4 0.3 0.094 12.6 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_31 PF13614.1 ETO13628.1 - 0.0068 16.3 0.0 2.5 7.9 0.0 2.7 1 1 1 2 2 2 1 AAA domain 6PF2K PF01591.13 ETO13628.1 - 0.02 13.9 0.1 0.075 12.0 0.0 2.0 2 0 0 2 2 2 0 6-phosphofructo-2-kinase APS_kinase PF01583.15 ETO13628.1 - 0.03 13.9 0.0 0.073 12.7 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase cobW PF02492.14 ETO13628.1 - 0.035 13.5 7.0 0.24 10.8 3.0 2.9 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain VirE PF05272.6 ETO13628.1 - 0.042 13.3 0.0 0.098 12.1 0.0 1.6 1 0 0 1 1 1 0 Virulence-associated protein E ATP_bind_1 PF03029.12 ETO13628.1 - 0.056 12.9 0.9 0.21 11.0 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.1 ETO13628.1 - 0.16 11.8 1.9 3.1 7.7 0.3 3.0 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 ETO13628.1 - 0.64 10.2 4.5 2.3 8.4 0.3 3.3 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETO13628.1 - 1.2 9.2 6.1 0.49 10.5 0.3 3.0 3 1 0 3 3 3 0 AAA domain Aldo_ket_red PF00248.16 ETO13629.1 - 2e-20 72.8 0.0 3.1e-18 65.5 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family Wzy_C PF04932.10 ETO13631.1 - 1.7 8.3 6.6 2.5 7.8 4.6 1.3 1 0 0 1 1 1 0 O-Antigen ligase Transferase PF02458.10 ETO13632.1 - 1.7e-10 39.9 0.0 4.7e-10 38.4 0.0 1.5 1 1 1 2 2 2 1 Transferase family RNA_pol_Rbc25 PF08292.7 ETO13636.1 - 0.057 13.6 0.2 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Rrp15p PF07890.7 ETO13638.1 - 5.6e-12 45.8 9.3 5.6e-12 45.8 6.5 1.7 1 1 1 2 2 2 1 Rrp15p Astro_capsid PF03115.9 ETO13638.1 - 0.27 9.4 9.5 0.32 9.1 6.6 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor RRM_1 PF00076.17 ETO13639.1 - 5.2e-15 54.8 0.4 5.1e-07 29.2 0.0 3.2 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO13639.1 - 1.9e-11 43.7 0.0 2.3e-06 27.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO13639.1 - 1.1e-07 31.5 0.0 0.0012 18.6 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF728 PF05304.7 ETO13639.1 - 0.32 11.2 3.4 1 9.5 0.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF728) MRI PF15325.1 ETO13641.1 - 2.6 9.0 8.6 6.9 7.6 4.5 2.2 2 0 0 2 2 2 0 Modulator of retrovirus infection 3-PAP PF12578.3 ETO13641.1 - 2.8 7.8 6.6 0.42 10.4 0.1 2.3 1 1 1 2 2 2 0 Myotubularin-associated protein DUF4134 PF13572.1 ETO13642.1 - 0.012 15.6 0.0 0.039 14.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4134) MnhB PF04039.8 ETO13642.1 - 0.46 10.5 4.4 0.47 10.5 0.1 2.5 2 1 0 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter IncA PF04156.9 ETO13644.1 - 0.12 11.9 1.2 0.17 11.4 0.8 1.2 1 0 0 1 1 1 0 IncA protein DUF342 PF03961.8 ETO13644.1 - 0.13 10.6 4.4 0.14 10.5 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) RhoGAP PF00620.22 ETO13645.1 - 9.6e-05 22.0 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain DUF2457 PF10446.4 ETO13647.1 - 0.0013 17.5 21.1 0.0022 16.8 14.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) PI3K_C2 PF00792.19 ETO13647.1 - 0.027 14.2 0.1 0.26 11.0 0.0 2.5 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 MDFI PF15316.1 ETO13647.1 - 0.028 14.3 0.1 0.061 13.3 0.1 1.5 1 0 0 1 1 1 0 MyoD family inhibitor CDC45 PF02724.9 ETO13647.1 - 1.3 6.9 11.9 1.9 6.4 8.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 ETO13647.1 - 1.5 8.3 9.4 3.3 7.2 6.5 1.7 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 ETO13647.1 - 2.1 6.1 20.0 3 5.6 13.8 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 ETO13647.1 - 2.5 6.4 18.1 4.3 5.7 12.5 1.3 1 0 0 1 1 1 0 Daxx Family Sporozoite_P67 PF05642.6 ETO13647.1 - 6.7 4.4 12.0 10 3.8 8.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.7 ETO13647.1 - 7.4 5.7 16.2 11 5.1 11.2 1.2 1 0 0 1 1 1 0 NOA36 protein PI3Ka PF00613.15 ETO13648.1 - 4.7e-32 110.6 2.8 5.1e-32 110.5 2.0 1.0 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Prp18 PF02840.10 ETO13649.1 - 0.043 13.6 3.2 0.9 9.3 0.2 2.2 1 1 1 2 2 2 0 Prp18 domain FtsK_SpoIIIE PF01580.13 ETO13649.1 - 0.11 11.9 0.0 0.26 10.7 0.0 1.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family PXA PF02194.10 ETO13650.1 - 0.032 13.7 0.3 0.043 13.3 0.2 1.1 1 0 0 1 1 1 0 PXA domain DUF4246 PF14033.1 ETO13651.1 - 0.93 8.0 20.1 0.06 11.9 8.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4246) DUF966 PF06136.8 ETO13651.1 - 1.2 8.5 22.2 2.7 7.3 7.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF966) Aminotran_5 PF00266.14 ETO13652.1 - 2.2e-72 243.8 0.1 1.9e-43 148.6 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.16 ETO13652.1 - 4.1e-07 29.4 0.0 3e-06 26.5 0.0 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 ETO13652.1 - 0.028 13.4 0.0 2.7 6.9 0.0 2.3 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 ETO13652.1 - 0.075 11.4 0.0 0.21 10.0 0.0 1.7 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain CRAL_TRIO PF00650.15 ETO13653.1 - 5.7e-20 71.3 3.6 3.7e-18 65.5 2.5 2.4 1 1 0 1 1 1 1 CRAL/TRIO domain RWD PF05773.17 ETO13653.1 - 0.033 14.0 2.9 0.14 12.0 1.9 2.5 1 1 0 1 1 1 0 RWD domain IncA PF04156.9 ETO13654.1 - 0.00067 19.3 0.4 0.045 13.3 0.0 2.2 2 0 0 2 2 2 1 IncA protein FGF-BP1 PF06473.7 ETO13654.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Peroxin-13_N PF04088.8 ETO13654.1 - 0.013 15.4 0.2 0.036 14.0 0.0 1.9 1 1 0 2 2 2 0 Peroxin 13, N-terminal region PEX11 PF05648.9 ETO13654.1 - 0.23 10.6 2.6 18 4.5 0.2 3.0 3 0 0 3 3 3 0 Peroxisomal biogenesis factor 11 (PEX11) DUF2370 PF10176.4 ETO13654.1 - 3.1 7.0 6.6 8.4 5.6 3.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2370) Bac_small_YrzI PF09501.5 ETO13655.1 - 5.3 7.0 8.1 4.8 7.1 1.7 2.7 2 1 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) HTH_38 PF13936.1 ETO13656.1 - 0.12 11.9 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain SNase PF00565.12 ETO13657.1 - 0.00079 19.6 0.2 0.0012 19.1 0.1 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue RRM_3 PF08777.6 ETO13657.1 - 0.11 12.2 0.4 1.2 9.0 0.1 2.2 1 1 1 2 2 2 0 RNA binding motif Ribosomal_S18 PF01084.15 ETO13657.1 - 0.13 12.1 0.8 0.34 10.8 0.1 2.0 2 1 1 3 3 3 0 Ribosomal protein S18 Herpes_heli_pri PF05774.6 ETO13658.1 - 3.1 7.7 7.7 0.078 12.9 0.3 2.1 2 0 0 2 2 2 0 Herpesvirus helicase-primase complex component Vfa1 PF08432.5 ETO13658.1 - 6.3 6.7 14.0 6.2 6.8 3.9 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 WD40 PF00400.27 ETO13660.1 - 3e-40 134.6 17.3 2.5e-10 39.8 0.2 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat zf-TRAF PF02176.13 ETO13660.1 - 1.5e-05 25.2 1.5 1.5e-05 25.2 1.1 2.9 3 0 0 3 3 3 1 TRAF-type zinc finger Kelch_6 PF13964.1 ETO13660.1 - 6.3e-05 22.9 5.1 0.036 14.2 0.1 3.8 3 0 0 3 3 3 1 Kelch motif Nup160 PF11715.3 ETO13660.1 - 8.6e-05 20.8 11.3 0.11 10.5 0.5 4.2 2 1 3 5 5 5 3 Nucleoporin Nup120/160 DUF3450 PF11932.3 ETO13660.1 - 2.6 7.2 13.8 0.48 9.6 6.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Ras PF00071.17 ETO13661.1 - 1.4e-45 154.6 0.5 1.5e-45 154.5 0.4 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.16 ETO13661.1 - 5.4e-11 42.0 0.1 5.7e-11 41.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 ETO13661.1 - 8.9e-11 42.3 0.0 1.3e-10 41.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 ETO13661.1 - 0.0016 17.9 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 ETO13661.1 - 0.021 13.9 0.0 0.022 13.8 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region BAR PF03114.13 ETO13662.1 - 3.9e-05 23.2 7.4 6.1e-05 22.6 5.1 1.2 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.8 ETO13662.1 - 0.0027 17.0 5.5 0.0047 16.3 3.8 1.4 1 0 0 1 1 1 1 Arfaptin-like domain CCDC-167 PF15188.1 ETO13662.1 - 0.025 14.5 2.4 0.63 10.0 2.7 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 FAM74 PF15026.1 ETO13662.1 - 0.065 12.8 0.2 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 FAM74 protein PhoU PF01895.14 ETO13662.1 - 0.13 12.7 0.6 0.2 12.1 0.4 1.4 1 0 0 1 1 1 0 PhoU domain HR1 PF02185.11 ETO13662.1 - 0.13 12.0 8.9 0.29 10.8 6.1 1.6 1 0 0 1 1 1 0 Hr1 repeat Adeno_PIX PF03955.9 ETO13662.1 - 0.78 10.2 5.0 0.15 12.5 0.8 1.9 2 1 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Peptidase_C98 PF15499.1 ETO13662.1 - 1.9 7.7 7.2 0.16 11.2 1.6 1.6 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase TPX2 PF06886.6 ETO13662.1 - 3.4 7.8 9.3 6 7.0 5.6 2.2 1 1 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) C2 PF00168.25 ETO13663.1 - 0.0033 17.2 0.2 0.013 15.2 0.0 2.0 2 0 0 2 2 2 1 C2 domain Noelin-1 PF12308.3 ETO13663.1 - 0.041 13.6 0.4 0.56 10.0 0.0 2.7 2 0 0 2 2 2 0 Neurogenesis glycoprotein Mit_ribos_Mrp51 PF11709.3 ETO13663.1 - 2.4 7.3 6.6 0.65 9.1 1.8 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal protein subunit BRI3BP PF14965.1 ETO13664.1 - 6.6 6.0 8.3 8.2 5.7 5.5 1.3 1 1 0 1 1 1 0 Negative regulator of p53/TP53 Pkinase PF00069.20 ETO13665.1 - 3.1e-57 193.6 0.0 3.7e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO13665.1 - 3.1e-24 85.4 0.0 4e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO13665.1 - 1.5e-08 33.9 0.0 2.2e-08 33.4 0.0 1.3 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 ETO13665.1 - 2.5e-07 30.6 0.0 2.3e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 ETO13665.1 - 3.8e-05 22.8 0.0 8.6e-05 21.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 ETO13665.1 - 0.0036 16.9 0.0 0.011 15.2 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 ETO13665.1 - 0.038 13.3 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 ETO13665.1 - 0.048 12.4 0.0 0.085 11.6 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase EcKinase PF02958.15 ETO13665.1 - 0.095 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase RabGAP-TBC PF00566.13 ETO13666.1 - 1.2e-09 37.9 1.9 3e-09 36.6 1.3 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain NPCBM_assoc PF10633.4 ETO13668.1 - 0.42 10.6 5.4 1.4 9.0 2.5 2.3 1 1 1 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase XAP5 PF04921.9 ETO13669.1 - 2.4 7.6 12.5 0.53 9.8 6.3 1.7 2 0 0 2 2 2 0 XAP5, circadian clock regulator DUF2371 PF10177.4 ETO13670.1 - 0.019 14.8 1.3 0.046 13.5 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) Cob_adeno_trans PF01923.13 ETO13671.1 - 0.055 13.2 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 Cobalamin adenosyltransferase LSM PF01423.17 ETO13672.1 - 7.5e-20 70.2 0.3 2.1e-19 68.8 0.2 1.7 2 0 0 2 2 2 1 LSM domain Gly-rich_Ago1 PF12764.2 ETO13672.1 - 0.058 14.0 0.5 0.085 13.4 0.3 1.2 1 0 0 1 1 1 0 Glycine-rich region of argonaut Toprim_Crpt PF13342.1 ETO13673.1 - 0.027 14.1 1.4 0.34 10.5 0.0 2.6 1 1 1 2 2 2 0 C-terminal repeat of topoisomerase Laminin_I PF06008.9 ETO13673.1 - 0.071 12.4 3.0 0.084 12.1 2.1 1.1 1 0 0 1 1 1 0 Laminin Domain I DREPP PF05558.7 ETO13673.1 - 0.11 12.3 1.3 0.14 12.0 0.9 1.2 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide Cortex-I_coil PF09304.5 ETO13673.1 - 0.12 12.4 3.7 0.82 9.7 0.7 2.0 1 1 1 2 2 2 0 Cortexillin I, coiled coil Atg14 PF10186.4 ETO13673.1 - 0.12 11.2 1.9 0.15 10.9 1.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 ETO13673.1 - 0.7 9.4 3.9 0.89 9.1 2.7 1.2 1 0 0 1 1 1 0 IncA protein SID-1_RNA_chan PF13965.1 ETO13674.1 - 9.3e-05 20.7 1.0 0.00011 20.5 0.7 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 DUF4242 PF14026.1 ETO13674.1 - 0.017 15.1 0.1 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4242) TEX19 PF15553.1 ETO13674.1 - 0.02 14.7 0.4 0.031 14.1 0.3 1.3 1 0 0 1 1 1 0 Testis-expressed protein 19 CENP-F_leu_zip PF10473.4 ETO13676.1 - 0.0013 18.5 5.9 0.0013 18.5 4.1 3.9 3 1 1 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 ETO13676.1 - 0.0021 17.2 4.3 0.0021 17.2 3.0 2.2 1 1 1 2 2 2 1 Reovirus sigma C capsid protein DUF1664 PF07889.7 ETO13676.1 - 0.01 15.6 5.1 0.01 15.6 3.6 3.7 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) Endonuc_Holl PF10107.4 ETO13676.1 - 0.015 14.9 2.0 0.015 14.9 1.4 3.6 2 1 2 4 4 4 0 Endonuclease related to archaeal Holliday junction resolvase WEMBL PF05701.6 ETO13676.1 - 0.017 13.5 34.3 0.026 12.9 23.8 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light EzrA PF06160.7 ETO13676.1 - 0.037 12.2 34.4 0.26 9.4 4.8 2.8 1 1 0 2 2 2 0 Septation ring formation regulator, EzrA DUF2935 PF11155.3 ETO13676.1 - 0.43 10.6 18.9 0.19 11.8 1.7 3.0 1 1 1 3 3 3 0 Domain of unknown function (DUF2935) TPR_MLP1_2 PF07926.7 ETO13676.1 - 0.92 9.2 48.2 2.3 7.9 5.6 4.2 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 ETO13676.1 - 2.2 7.2 49.2 0.093 11.7 8.8 2.8 1 1 1 3 3 3 0 Autophagy protein Apg6 GAS PF13851.1 ETO13676.1 - 2.5 7.2 46.0 0.12 11.5 5.8 3.6 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 ETO13676.1 - 3.1 7.3 43.9 58 3.1 15.4 4.4 2 1 2 4 4 4 0 IncA protein bZIP_1 PF00170.16 ETO13676.1 - 4.1 7.4 33.9 0.44 10.5 3.1 5.9 2 1 3 6 6 6 0 bZIP transcription factor Filament PF00038.16 ETO13676.1 - 5.4 6.3 42.4 3.9 6.8 15.2 2.4 1 1 1 2 2 2 0 Intermediate filament protein TMEM237 PF15383.1 ETO13678.1 - 0.021 13.9 0.0 0.05 12.7 0.0 1.6 1 0 0 1 1 1 0 Transmembrane protein 237 DUF3228 PF11539.3 ETO13679.1 - 6.5e-67 224.4 0.0 8.6e-67 224.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) Crinivirus_P26 PF07416.6 ETO13679.1 - 0.0044 16.5 0.0 0.0069 15.9 0.0 1.2 1 0 0 1 1 1 1 Crinivirus P26 protein CBFD_NFYB_HMF PF00808.18 ETO13679.1 - 0.12 12.4 0.2 0.31 11.1 0.1 1.7 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF747 PF05346.6 ETO13680.1 - 6.5e-50 170.0 8.3 8.3e-50 169.7 5.7 1.0 1 0 0 1 1 1 1 Eukaryotic membrane protein family TPR_MLP1_2 PF07926.7 ETO13681.1 - 0.0039 16.9 10.5 0.0039 16.9 7.3 4.6 2 1 2 4 4 4 1 TPR/MLP1/MLP2-like protein DUF3450 PF11932.3 ETO13681.1 - 0.016 14.4 0.8 0.016 14.4 0.6 5.3 5 1 1 6 6 6 0 Protein of unknown function (DUF3450) MerB PF03243.10 ETO13681.1 - 0.058 13.2 0.4 0.058 13.2 0.3 1.9 2 0 0 2 2 2 0 Alkylmercury lyase DUF1664 PF07889.7 ETO13681.1 - 1.8 8.4 30.7 2.1 8.1 3.6 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 ETO13681.1 - 2.2 7.3 15.1 1.8 7.6 1.3 3.1 2 1 1 4 4 4 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 ETO13681.1 - 3.1 6.1 45.1 0.057 11.8 8.4 3.0 1 1 1 2 2 2 0 AAA domain Cep57_CLD_2 PF14197.1 ETO13682.1 - 0.016 15.1 11.1 0.016 15.1 7.7 6.2 4 2 2 6 6 6 0 Centrosome localisation domain of PPC89 zf-MYND PF01753.13 ETO13683.1 - 5.1e-08 32.6 9.8 5.1e-08 32.6 6.8 2.1 2 0 0 2 2 2 1 MYND finger DARPP-32 PF05395.7 ETO13683.1 - 0.27 11.3 16.0 0.029 14.5 7.7 1.9 2 0 0 2 2 2 0 Protein phosphatase inhibitor 1/DARPP-32 DUF4551 PF15087.1 ETO13683.1 - 1 7.6 11.8 1.6 7.0 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) ATP11 PF06644.6 ETO13683.1 - 1.2 8.5 12.7 2 7.8 8.8 1.2 1 0 0 1 1 1 0 ATP11 protein Pex16 PF08610.5 ETO13683.1 - 9.5 5.1 7.4 15 4.4 5.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) RhoGEF PF00621.15 ETO13684.1 - 1.4e-10 41.3 0.3 1.7e-10 41.1 0.2 1.1 1 0 0 1 1 1 1 RhoGEF domain CDK5_activator PF03261.10 ETO13685.1 - 0.58 9.4 15.9 0.69 9.1 11.0 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein PAT1 PF09770.4 ETO13685.1 - 0.92 7.6 46.8 0.99 7.5 32.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 ETO13685.1 - 2.4 6.2 51.1 2.5 6.1 35.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF605 PF04652.11 ETO13685.1 - 5.8 6.2 30.8 7.1 5.9 21.4 1.1 1 0 0 1 1 1 0 Vta1 like KSR1-SAM PF13543.1 ETO13687.1 - 0.061 13.1 0.1 0.1 12.3 0.1 1.4 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 Phosphoprotein PF00922.12 ETO13687.1 - 0.28 10.3 0.0 0.28 10.3 0.0 2.9 2 1 1 3 3 3 0 Vesiculovirus phosphoprotein SR-25 PF10500.4 ETO13688.1 - 0.42 10.0 4.5 0.73 9.2 3.1 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Daxx PF03344.10 ETO13689.1 - 0.0013 17.3 19.0 0.0015 17.1 13.1 1.1 1 0 0 1 1 1 1 Daxx Family ArsC PF03960.10 ETO13689.1 - 0.0057 16.7 0.4 0.01 15.8 0.3 1.4 1 0 0 1 1 1 1 ArsC family Nop14 PF04147.7 ETO13689.1 - 0.16 9.8 24.9 0.19 9.6 17.3 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 ETO13689.1 - 0.31 10.2 23.7 0.39 9.9 16.5 1.2 1 0 0 1 1 1 0 SDA1 DUF605 PF04652.11 ETO13689.1 - 0.32 10.3 15.3 0.47 9.8 10.6 1.3 1 0 0 1 1 1 0 Vta1 like Hid1 PF12722.2 ETO13689.1 - 0.67 7.5 18.0 0.79 7.3 12.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Menin PF05053.8 ETO13689.1 - 3.1 5.8 10.9 3.5 5.6 7.6 1.2 1 0 0 1 1 1 0 Menin RGS PF00615.14 ETO13690.1 - 0.0011 19.0 14.2 0.019 15.0 1.2 3.7 3 1 0 3 3 3 2 Regulator of G protein signaling domain Vfa1 PF08432.5 ETO13691.1 - 0.012 15.6 1.5 0.012 15.6 1.0 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 RRN3 PF05327.6 ETO13691.1 - 5.9 4.8 5.7 8.7 4.3 4.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ERAP1_C PF11838.3 ETO13693.1 - 6.5e-54 183.3 0.4 7.5e-54 183.1 0.3 1.0 1 0 0 1 1 1 1 ERAP1-like C-terminal domain HEAT_2 PF13646.1 ETO13693.1 - 0.0028 17.9 0.2 0.13 12.5 0.0 3.0 2 2 2 4 4 4 1 HEAT repeats Peptidase_M1 PF01433.15 ETO13694.1 - 8.4e-76 255.5 0.8 3.6e-61 207.3 0.2 2.1 2 0 0 2 2 2 2 Peptidase family M1 Peptidase_MA_2 PF13485.1 ETO13694.1 - 9.6e-19 67.6 0.1 1.3e-18 67.2 0.1 1.2 1 0 0 1 1 1 1 Peptidase MA superfamily FH2 PF02181.18 ETO13695.1 - 1.7e-89 300.3 10.8 1.7e-89 300.3 7.5 2.1 1 1 1 2 2 2 1 Formin Homology 2 Domain DUF2360 PF10152.4 ETO13695.1 - 4.4e-12 46.5 23.4 2.6e-06 27.8 3.4 4.7 5 0 0 5 5 5 2 Predicted coiled-coil domain-containing protein (DUF2360) PT PF04886.7 ETO13696.1 - 0.003 16.8 20.9 0.034 13.4 14.5 2.5 1 1 0 1 1 1 1 PT repeat DUF972 PF06156.8 ETO13696.1 - 0.036 14.4 1.6 0.036 14.4 1.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Nucleoside_tran PF01733.13 ETO13696.1 - 0.57 9.2 2.4 0.46 9.6 1.1 1.3 1 1 0 1 1 1 0 Nucleoside transporter LMBR1 PF04791.11 ETO13696.1 - 1.1 7.7 3.6 1.1 7.6 2.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein AAA PF00004.24 ETO13697.1 - 5.7e-31 107.4 0.0 2.6e-30 105.3 0.0 2.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETO13697.1 - 2.1e-06 27.9 0.1 0.00037 20.6 0.1 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 ETO13697.1 - 1.5e-05 24.2 0.0 2.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 ETO13697.1 - 0.00014 21.5 0.0 0.00088 19.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 ETO13697.1 - 0.00024 20.5 0.3 0.0017 17.7 0.1 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.1 ETO13697.1 - 0.00035 21.3 0.0 0.00063 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 ETO13697.1 - 0.0012 18.2 0.2 0.15 11.4 0.1 2.2 1 1 1 2 2 2 1 AAA domain MIT PF04212.13 ETO13697.1 - 0.0016 18.2 1.6 0.0032 17.3 1.1 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TIP49 PF06068.8 ETO13697.1 - 0.0024 16.6 0.0 0.0048 15.6 0.0 1.6 1 0 0 1 1 1 1 TIP49 C-terminus AAA_2 PF07724.9 ETO13697.1 - 0.003 17.4 0.0 0.0096 15.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 ETO13697.1 - 0.0034 17.3 0.1 1.3 8.9 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 ETO13697.1 - 0.0045 16.8 0.0 0.016 15.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 ETO13697.1 - 0.012 15.5 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 ETO13697.1 - 0.013 14.7 0.5 0.039 13.1 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 ETO13697.1 - 0.013 15.2 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 ETO13697.1 - 0.064 12.3 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Guanylate_kin PF00625.16 ETO13697.1 - 0.074 12.4 0.5 2.7 7.4 0.0 2.9 2 1 1 3 3 3 0 Guanylate kinase RNA_helicase PF00910.17 ETO13697.1 - 0.083 13.0 0.0 0.26 11.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Ebola_NP PF05505.7 ETO13698.1 - 0.59 8.1 17.3 0.66 7.9 12.0 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein Lin-8 PF03353.10 ETO13698.1 - 0.71 9.1 12.6 0.91 8.7 8.7 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist U3_snoRNA_assoc PF08297.6 ETO13698.1 - 0.81 9.9 6.4 2.1 8.6 4.5 1.8 1 1 0 1 1 1 0 U3 snoRNA associated CDC45 PF02724.9 ETO13698.1 - 0.87 7.5 10.8 0.89 7.5 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 ETO13698.1 - 5.4 4.5 15.8 5.9 4.4 10.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Apyrase PF06079.6 ETO13699.1 - 0.026 13.6 0.1 0.048 12.8 0.1 1.6 1 1 1 2 2 2 0 Apyrase DUF4019 PF13211.1 ETO13699.1 - 0.09 13.0 0.0 0.22 11.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4019) PYST-C1 PF09690.5 ETO13699.1 - 5.3 6.7 8.8 1.9 8.1 1.8 2.4 2 0 0 2 2 2 0 Plasmodium yoelii subtelomeric region (PYST-C1) DUF4479 PF14794.1 ETO13700.1 - 0.08 12.4 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4479) DEAD PF00270.24 ETO13701.1 - 2.2e-45 154.2 0.0 2.8e-43 147.3 0.0 3.0 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 ETO13701.1 - 1.2e-24 86.0 0.9 2.2e-24 85.1 0.2 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Exo70 PF03081.10 ETO13702.1 - 5.3e-48 163.6 21.3 1.3e-46 159.1 6.5 3.8 4 0 0 4 4 4 3 Exo70 exocyst complex subunit Pyr_redox PF00070.22 ETO13703.1 - 1.9e-16 60.2 0.1 8.8e-16 58.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETO13703.1 - 4.4e-10 39.7 0.6 1.9e-08 34.4 0.7 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETO13703.1 - 1.7e-08 34.7 0.0 1.1e-07 32.1 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 ETO13703.1 - 0.0043 17.2 0.1 0.017 15.3 0.0 2.0 2 1 0 2 2 2 1 Putative NAD(P)-binding DAO PF01266.19 ETO13703.1 - 0.0062 15.4 0.0 0.013 14.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 ETO13703.1 - 0.013 14.4 0.2 0.96 8.2 0.0 2.6 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 ETO13703.1 - 0.014 15.4 0.3 0.74 9.9 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 ETO13703.1 - 0.015 13.7 0.7 0.075 11.4 0.0 2.4 3 0 0 3 3 3 0 HI0933-like protein GIDA PF01134.17 ETO13703.1 - 0.15 10.8 3.1 0.5 9.1 0.1 2.8 2 2 1 3 3 3 0 Glucose inhibited division protein A LRR_4 PF12799.2 ETO13704.1 - 2.8e-09 36.3 27.2 3.4e-05 23.3 2.2 3.7 2 2 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 ETO13704.1 - 4.5e-07 29.5 2.4 7.8e-07 28.8 1.7 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 ETO13704.1 - 3.3e-06 26.7 20.2 0.0011 18.6 5.3 2.9 1 1 3 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 ETO13704.1 - 0.0012 18.5 15.3 4 7.8 0.4 5.3 5 1 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 ETO13704.1 - 0.035 14.2 12.9 4.4 7.9 0.0 5.1 5 0 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 ETO13704.1 - 3.4 8.0 23.6 3.8 7.8 0.3 5.3 5 1 0 5 5 5 0 Leucine Rich repeat Acetyltransf_7 PF13508.1 ETO13706.1 - 3.3e-09 36.7 0.0 7.2e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETO13706.1 - 9.7e-06 25.5 0.0 1.9e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 ETO13706.1 - 0.0041 17.2 0.0 0.0071 16.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETO13706.1 - 0.0065 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acyl-ACP_TE PF01643.12 ETO13706.1 - 0.026 13.4 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 Acyl-ACP thioesterase Acetyltransf_8 PF13523.1 ETO13706.1 - 0.027 14.3 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 ETO13706.1 - 0.12 12.3 1.0 3.3 7.6 0.1 2.6 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Fels1 PF05666.6 ETO13707.1 - 0.05 12.9 0.0 0.15 11.4 0.0 1.8 1 0 0 1 1 1 0 Fels-1 Prophage Protein-like EzrA PF06160.7 ETO13708.1 - 2.7e-05 22.5 2.9 2.7e-05 22.5 2.0 3.1 3 0 0 3 3 2 1 Septation ring formation regulator, EzrA KdpD PF02702.12 ETO13708.1 - 0.0032 16.6 0.4 0.0055 15.8 0.0 1.6 2 0 0 2 2 2 1 Osmosensitive K+ channel His kinase sensor domain Frag1 PF10277.4 ETO13708.1 - 0.016 14.7 7.0 0.024 14.1 4.8 1.2 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family Sialidase PF02973.11 ETO13708.1 - 0.02 13.8 0.6 0.054 12.4 0.1 1.8 1 1 0 1 1 1 0 Sialidase, N-terminal domain Hom_end PF05204.9 ETO13708.1 - 0.33 10.9 5.0 0.36 10.8 1.1 2.3 2 0 0 2 2 2 0 Homing endonuclease 7tm_1 PF00001.16 ETO13708.1 - 0.38 9.8 6.2 0.6 9.1 4.3 1.5 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) NYD-SP28_assoc PF14775.1 ETO13708.1 - 0.4 10.4 5.9 0.27 10.9 2.2 2.1 2 0 0 2 2 2 0 Sperm tail C-terminal domain DUF607 PF04678.8 ETO13708.1 - 0.77 9.6 14.4 2.4 8.0 0.7 3.4 3 1 0 3 3 3 0 Protein of unknown function, DUF607 NPV_P10 PF05531.7 ETO13708.1 - 1.1 9.6 24.7 1.5 9.1 0.1 4.9 3 2 2 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 ETO13708.1 - 1.2 8.8 12.8 0.063 13.0 1.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DivIC PF04977.10 ETO13708.1 - 1.7 8.2 26.6 0.66 9.5 0.5 4.7 3 2 0 4 4 4 0 Septum formation initiator THP2 PF09432.5 ETO13708.1 - 1.7 8.5 8.2 15 5.4 0.2 3.1 2 1 0 2 2 2 0 Tho complex subunit THP2 Med4 PF10018.4 ETO13708.1 - 3 7.1 15.5 0.06 12.7 2.7 2.6 1 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF2951 PF11166.3 ETO13708.1 - 3.1 7.7 11.0 5.2 6.9 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2951) Reo_sigmaC PF04582.7 ETO13708.1 - 6 5.9 14.0 0.34 10.0 2.4 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF2422 PF10337.4 ETO13708.1 - 7.9 5.1 11.4 1.5 7.5 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2422) TPR_MLP1_2 PF07926.7 ETO13708.1 - 9.7 5.9 46.8 0.28 10.9 3.4 3.6 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF883 PF05957.8 ETO13709.1 - 0.0068 16.7 2.9 0.0068 16.7 2.0 6.1 2 2 6 9 9 9 1 Bacterial protein of unknown function (DUF883) DUF869 PF05911.6 ETO13709.1 - 0.077 11.2 77.1 0.0053 15.0 26.5 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) ADIP PF11559.3 ETO13709.1 - 0.38 10.6 101.5 1.3 8.9 16.6 5.4 1 1 3 5 5 5 0 Afadin- and alpha -actinin-Binding Filament PF00038.16 ETO13709.1 - 5.9 6.2 88.3 3.5 7.0 17.5 5.1 1 1 3 5 5 5 0 Intermediate filament protein Reo_sigmaC PF04582.7 ETO13709.1 - 6.8 5.7 22.5 2.4 7.2 2.9 3.8 1 1 3 4 4 4 0 Reovirus sigma C capsid protein GAS PF13851.1 ETO13709.1 - 8.1 5.5 97.6 0.29 10.2 30.0 4.3 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding DUF2746 PF10874.3 ETO13710.1 - 0.027 14.6 0.2 0.07 13.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) DUF745 PF05335.8 ETO13710.1 - 0.054 13.0 1.8 0.074 12.5 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Troponin PF00992.15 ETO13710.1 - 0.06 13.4 5.6 0.11 12.6 3.9 1.4 1 0 0 1 1 1 0 Troponin IncA PF04156.9 ETO13710.1 - 0.076 12.5 8.6 0.1 12.1 6.0 1.3 1 0 0 1 1 1 0 IncA protein TPR_MLP1_2 PF07926.7 ETO13710.1 - 0.083 12.6 11.8 0.33 10.7 5.6 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein EAP30 PF04157.11 ETO13710.1 - 0.1 11.7 2.8 0.17 11.0 2.0 1.3 1 0 0 1 1 1 0 EAP30/Vps36 family Antimicrobial19 PF08225.6 ETO13710.1 - 0.13 11.7 1.1 0.51 9.7 0.8 2.0 1 1 0 1 1 1 0 Pseudin antimicrobial peptide FlxA PF14282.1 ETO13710.1 - 0.23 11.3 8.0 0.5 10.3 5.4 1.8 1 1 0 1 1 1 0 FlxA-like protein DUF342 PF03961.8 ETO13710.1 - 0.61 8.4 6.4 0.79 8.0 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PX PF00787.19 ETO13711.1 - 0.01 15.6 5.8 0.14 11.9 2.7 3.2 2 1 0 2 2 2 0 PX domain WD40 PF00400.27 ETO13712.1 - 1.1e-96 313.6 32.5 1.8e-11 43.4 0.0 13.7 13 1 0 13 13 13 11 WD domain, G-beta repeat NACHT PF05729.7 ETO13712.1 - 1.3e-07 31.4 0.0 5.7e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 NACHT domain Pentapeptide PF00805.17 ETO13712.1 - 1.3e-06 27.5 1.9 3.6e-06 26.0 1.3 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO13712.1 - 2.5e-05 23.9 1.8 2.5e-05 23.9 1.3 1.9 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 ETO13712.1 - 0.00017 21.4 0.5 0.00017 21.4 0.3 2.1 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) AAA_18 PF13238.1 ETO13712.1 - 0.00021 21.5 4.5 0.00038 20.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain PD40 PF07676.7 ETO13712.1 - 0.00064 19.3 13.8 0.79 9.4 0.0 7.3 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat AAA_22 PF13401.1 ETO13712.1 - 0.0012 18.9 0.0 0.0047 17.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO13712.1 - 0.0052 17.5 0.0 0.029 15.1 0.0 2.4 1 0 0 1 1 1 1 AAA domain TPR_12 PF13424.1 ETO13713.1 - 1.1e-38 131.0 23.2 1.5e-15 56.8 1.4 3.8 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO13713.1 - 1.1e-17 63.3 0.0 5.8e-05 22.8 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO13713.1 - 2.1e-12 46.5 17.5 7.5e-09 35.1 2.8 3.3 2 1 1 3 3 3 3 TPR repeat TPR_7 PF13176.1 ETO13713.1 - 6.8e-11 41.1 5.6 0.0057 16.3 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO13713.1 - 1.7e-10 40.0 19.1 3.9e-06 26.2 0.1 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO13713.1 - 4.6e-09 35.5 16.1 0.00063 19.4 0.1 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO13713.1 - 2.4e-07 30.0 23.4 0.0024 17.5 0.2 4.9 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO13713.1 - 0.0029 17.9 7.0 5 7.8 0.1 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO13713.1 - 0.0035 17.4 8.9 3.2 8.1 0.2 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO13713.1 - 0.0051 17.3 0.0 4.8 8.0 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO13713.1 - 0.095 13.4 0.0 2.3 9.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Kelch_6 PF13964.1 ETO13714.1 - 7.1e-06 25.9 2.1 0.022 14.9 0.0 4.0 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO13714.1 - 8.6e-06 25.4 0.2 8.4e-05 22.2 0.0 2.8 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO13714.1 - 0.0019 17.6 0.4 2.8 7.5 0.0 3.5 3 1 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 ETO13714.1 - 0.021 14.7 0.2 1.8 8.6 0.0 3.3 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.10 ETO13714.1 - 0.022 14.5 0.7 8.8 6.2 0.0 3.7 4 0 0 4 4 4 0 Kelch motif SMI1_KNR4 PF09346.5 ETO13714.1 - 0.086 12.8 2.0 0.42 10.6 0.1 2.6 2 1 1 3 3 3 0 SMI1 / KNR4 family (SUKH-1) HHH_8 PF14716.1 ETO13715.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Helix-hairpin-helix domain CagX PF03524.10 ETO13716.1 - 0.039 13.2 0.1 0.045 13.0 0.1 1.1 1 0 0 1 1 1 0 Conjugal transfer protein GOLD_2 PF13897.1 ETO13716.1 - 0.04 14.1 0.6 0.048 13.8 0.4 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking zf-RING_2 PF13639.1 ETO13717.1 - 1.4e-09 37.6 10.1 1.4e-09 37.6 7.0 3.1 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 ETO13717.1 - 1.3e-08 34.3 6.3 1.3e-08 34.3 4.4 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO13717.1 - 1.2e-06 28.0 9.7 1.2e-06 28.0 6.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETO13717.1 - 6.7e-05 22.9 5.6 6.7e-05 22.9 3.9 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 ETO13717.1 - 0.00029 20.4 8.0 0.00029 20.4 5.6 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 ETO13717.1 - 0.00032 20.6 10.9 0.00032 20.6 7.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 ETO13717.1 - 0.00087 19.0 3.7 0.0022 17.7 2.6 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Mito_carr PF00153.22 ETO13717.1 - 0.26 11.0 7.0 0.37 10.5 0.1 3.7 3 2 1 4 4 4 0 Mitochondrial carrier protein DUF3635 PF12330.3 ETO13717.1 - 0.38 10.8 0.0 0.38 10.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3635) EF-hand_1 PF00036.27 ETO13718.1 - 3.7e-33 110.2 25.8 1.8e-09 36.1 0.7 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 ETO13718.1 - 9.8e-29 99.2 13.1 1.2e-14 54.1 1.6 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 ETO13718.1 - 5.9e-25 85.4 23.4 2.9e-09 35.8 1.1 5.0 4 1 1 5 5 5 4 EF hand EF-hand_6 PF13405.1 ETO13718.1 - 4.4e-24 82.1 19.4 6.3e-08 31.8 0.9 5.2 3 3 3 6 6 6 4 EF-hand domain EF-hand_8 PF13833.1 ETO13718.1 - 1.7e-22 78.7 26.5 9.8e-15 53.9 4.3 3.8 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.1 ETO13718.1 - 1.2e-12 47.5 0.9 3.2e-05 23.7 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 ETO13718.1 - 1.8e-09 37.5 1.7 0.00024 21.1 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 ETO13718.1 - 1.9e-08 34.0 10.9 0.00011 21.9 0.4 3.0 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 ETO13718.1 - 1.9e-05 24.3 0.3 0.046 13.2 0.0 2.5 2 1 0 2 2 2 2 Caleosin related protein TerB PF05099.8 ETO13718.1 - 2.7e-05 23.9 6.0 0.018 14.7 0.1 2.9 3 1 0 3 3 3 2 Tellurite resistance protein TerB tRNA_synt_1c_R1 PF04558.10 ETO13718.1 - 0.0052 16.3 0.3 2.7 7.5 0.0 2.2 2 0 0 2 2 2 2 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 EF-hand_10 PF14788.1 ETO13718.1 - 0.015 14.9 7.5 0.028 14.0 0.6 2.8 3 0 0 3 3 3 0 EF hand DUF3879 PF12995.2 ETO13718.1 - 0.036 13.6 0.2 1.3 8.5 0.0 2.9 1 1 1 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3879) DUF1296 PF06972.6 ETO13718.1 - 0.047 13.6 0.2 1.5 8.8 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) Acetyltransf_11 PF13720.1 ETO13718.1 - 0.061 13.5 0.0 7.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF1456 PF07308.8 ETO13718.1 - 0.061 13.3 3.8 1.3 9.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) DUF1241 PF06840.6 ETO13718.1 - 0.1 11.8 0.9 0.18 11.0 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1241) DUF3349 PF11829.3 ETO13718.1 - 0.14 12.5 0.2 16 5.9 0.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) VCBS PF13517.1 ETO13718.1 - 0.79 10.1 11.2 48 4.4 0.3 4.0 3 1 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF2457 PF10446.4 ETO13721.1 - 0.047 12.4 20.5 0.058 12.1 14.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Menin PF05053.8 ETO13721.1 - 0.51 8.4 9.0 0.55 8.3 6.3 1.1 1 0 0 1 1 1 0 Menin Lin-8 PF03353.10 ETO13721.1 - 0.61 9.3 11.5 0.86 8.8 7.9 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SPC25 PF06703.6 ETO13722.1 - 0.027 14.0 3.6 0.051 13.1 2.5 1.4 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) O-antigen_lig PF13425.1 ETO13722.1 - 0.16 11.9 2.3 0.14 12.0 0.7 1.5 1 1 0 1 1 1 0 O-antigen ligase like membrane protein Wzy_C PF04932.10 ETO13722.1 - 0.19 11.5 1.2 0.3 10.8 0.8 1.3 1 0 0 1 1 1 0 O-Antigen ligase DNA_pol_viral_N PF00242.12 ETO13722.1 - 0.53 9.2 9.0 0.67 8.9 6.3 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain WD40 PF00400.27 ETO13723.1 - 0.00043 20.0 0.0 0.00079 19.2 0.0 1.4 1 0 0 1 1 1 1 WD domain, G-beta repeat VID27 PF08553.5 ETO13723.1 - 0.14 10.4 0.0 0.14 10.4 0.0 3.0 3 0 0 3 3 3 0 VID27 cytoplasmic protein Prothymosin PF03247.9 ETO13723.1 - 2.1 8.5 50.3 3.5 7.8 16.7 2.3 2 0 0 2 2 2 0 Prothymosin/parathymosin family Peptidase_S64 PF08192.6 ETO13723.1 - 2.6 6.2 14.4 3.1 6.0 10.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 Pox_RNA_Pol_19 PF05320.7 ETO13723.1 - 3 7.5 23.9 0.67 9.6 6.2 2.3 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit HNOBA PF07701.9 ETO13723.1 - 3.5 6.7 10.4 8.6 5.4 3.6 2.2 2 0 0 2 2 2 0 Heme NO binding associated Apc15p PF05841.6 ETO13724.1 - 1.9 9.2 9.5 2.8 8.6 3.2 2.2 2 0 0 2 2 2 0 Apc15p protein DUF912 PF06024.7 ETO13724.1 - 6.5 6.8 19.2 9 6.4 0.4 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) UPF0542 PF15086.1 ETO13728.1 - 0.17 11.6 7.2 0.036 13.7 2.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 WBP-1 PF11669.3 ETO13728.1 - 0.19 11.8 4.8 1.5 8.9 0.1 2.8 1 1 2 3 3 3 0 WW domain-binding protein 1 AAA PF00004.24 ETO13729.1 - 2.5e-41 140.9 0.2 8.4e-30 103.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 ETO13729.1 - 2.2e-06 28.4 0.2 0.0052 17.5 0.1 2.8 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 ETO13729.1 - 5.1e-06 26.6 7.0 0.011 15.8 1.7 3.8 3 1 0 3 3 2 1 AAA domain TIP49 PF06068.8 ETO13729.1 - 2.7e-05 23.0 0.0 0.0064 15.2 0.0 2.5 2 0 0 2 2 2 1 TIP49 C-terminus RNA_helicase PF00910.17 ETO13729.1 - 9.4e-05 22.5 0.0 0.041 14.0 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.1 ETO13729.1 - 0.00011 22.4 0.7 0.00096 19.4 0.1 2.7 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 ETO13729.1 - 0.00011 21.6 0.0 0.0031 16.9 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_5 PF07728.9 ETO13729.1 - 0.00028 20.6 0.4 0.001 18.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 ETO13729.1 - 0.00046 20.0 0.6 0.069 13.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 ETO13729.1 - 0.00089 19.2 0.0 0.0037 17.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 ETO13729.1 - 0.0012 18.5 0.2 0.012 15.3 0.1 2.4 2 0 0 2 2 2 1 Part of AAA domain Mg_chelatase PF01078.16 ETO13729.1 - 0.0015 17.7 0.0 0.0027 16.8 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 ETO13729.1 - 0.0027 17.6 0.1 0.011 15.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 ETO13729.1 - 0.0041 16.9 0.0 0.066 13.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 ETO13729.1 - 0.0043 16.4 0.2 0.2 11.0 0.0 2.5 2 1 1 3 3 3 1 AAA domain ABC_tran PF00005.22 ETO13729.1 - 0.0044 17.3 0.8 0.035 14.4 0.0 2.9 3 1 0 3 3 3 1 ABC transporter NACHT PF05729.7 ETO13729.1 - 0.013 15.1 0.0 0.38 10.3 0.0 2.8 2 1 0 2 2 2 0 NACHT domain RuvB_N PF05496.7 ETO13729.1 - 0.014 14.4 0.0 0.033 13.2 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 ETO13729.1 - 0.015 14.8 0.3 0.042 13.4 0.2 1.7 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 ETO13729.1 - 0.025 14.2 0.3 0.55 9.8 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 ETO13729.1 - 0.027 14.0 0.0 0.067 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 ETO13729.1 - 0.049 12.6 0.0 0.1 11.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.21 ETO13729.1 - 0.056 12.9 0.0 0.2 11.1 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 ETO13729.1 - 0.068 13.1 0.0 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 ETO13729.1 - 0.13 12.6 2.3 0.11 12.7 0.2 2.1 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 ETO13729.1 - 0.19 11.4 6.4 13 5.4 0.0 3.7 3 1 1 4 4 4 0 Archaeal ATPase NicO PF03824.11 ETO13730.1 - 0.22 10.7 2.2 0.14 11.4 0.4 1.4 2 0 0 2 2 2 0 High-affinity nickel-transport protein Mitofilin PF09731.4 ETO13731.1 - 3.8 6.0 46.2 6.6 5.2 32.0 1.4 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CRT-like PF08627.5 ETO13732.1 - 0.13 12.2 1.0 0.18 11.7 0.1 1.7 2 0 0 2 2 2 0 CRT-like Cation_efflux PF01545.16 ETO13733.1 - 4e-26 91.7 26.5 3.8e-24 85.2 18.4 2.9 1 1 0 1 1 1 1 Cation efflux family DUF2207 PF09972.4 ETO13734.1 - 0.099 11.2 0.0 0.099 11.2 0.0 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Stress-antifung PF01657.12 ETO13734.1 - 0.13 12.5 2.8 0.15 12.4 0.8 1.9 1 1 1 2 2 2 0 Salt stress response/antifungal CstA PF02554.9 ETO13734.1 - 3.7 6.0 20.8 3 6.4 10.2 2.0 2 0 0 2 2 2 0 Carbon starvation protein CstA MRI PF15325.1 ETO13735.1 - 0.039 14.9 7.4 0.039 14.9 5.1 2.5 2 1 0 2 2 2 0 Modulator of retrovirus infection DUF2547 PF10818.3 ETO13735.1 - 0.22 12.1 3.6 1.6 9.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) T2SM PF04612.7 ETO13735.1 - 6.5 6.5 7.0 5.6 6.7 0.1 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M Nexin_C PF08628.7 ETO13736.1 - 4.8e-15 55.6 0.2 4.8e-15 55.6 0.1 3.1 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.19 ETO13736.1 - 3.3e-05 23.6 0.1 0.00015 21.4 0.1 2.2 1 0 0 1 1 1 1 PX domain DUF3159 PF11361.3 ETO13736.1 - 1.1 8.7 2.6 0.92 8.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3159) PXA PF02194.10 ETO13737.1 - 2.1e-09 37.2 0.0 2.1e-09 37.2 0.0 2.5 3 0 0 3 3 3 1 PXA domain PXA PF02194.10 ETO13738.1 - 1.5e-05 24.6 0.1 2.4e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 PXA domain CDC27 PF09507.5 ETO13739.1 - 1.6 7.8 38.2 1.9 7.5 26.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ank_5 PF13857.1 ETO13740.1 - 4.7e-10 39.3 2.5 7.3e-07 29.2 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO13740.1 - 2.3e-09 37.4 1.4 0.00039 20.8 0.3 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO13740.1 - 3.3e-09 36.9 0.2 8.5e-09 35.6 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) LMBR1 PF04791.11 ETO13740.1 - 8.3e-07 27.9 0.0 5.5e-06 25.2 0.0 1.9 1 1 1 2 2 2 1 LMBR1-like membrane protein Ank PF00023.25 ETO13740.1 - 0.00019 21.0 2.4 0.31 10.9 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 ETO13740.1 - 0.00041 20.3 0.8 1.8 9.0 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat FPL PF09758.4 ETO13741.1 - 9.7e-35 119.5 9.4 1.7e-34 118.7 6.5 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein SelP_N PF04592.9 ETO13742.1 - 0.01 15.2 12.3 0.01 15.2 8.5 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Zip PF02535.17 ETO13742.1 - 0.48 9.3 13.5 0.018 14.0 3.9 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter Pex2_Pex12 PF04757.9 ETO13744.1 - 2.7e-26 92.4 7.1 3.7e-26 91.9 4.9 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 ETO13744.1 - 3.8e-07 29.8 18.4 9.5e-07 28.5 12.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 ETO13744.1 - 5.8e-07 29.0 15.0 1.1e-06 28.2 10.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO13744.1 - 1.8e-06 27.8 19.2 4.8e-06 26.5 13.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO13744.1 - 7.2e-05 22.4 14.8 0.00016 21.3 10.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 ETO13744.1 - 0.00057 19.4 18.3 0.0016 18.0 12.7 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETO13744.1 - 0.0091 16.0 11.4 0.023 14.8 7.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger U-box PF04564.10 ETO13744.1 - 0.07 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 U-box domain zf-C3HC4_4 PF15227.1 ETO13744.1 - 0.61 10.0 21.5 0.16 11.8 12.2 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 ETO13744.1 - 5.6 6.7 12.5 3 7.6 6.6 2.2 2 1 0 2 2 2 0 RING-type zinc-finger G-alpha PF00503.15 ETO13745.1 - 3e-89 299.4 9.4 2e-87 293.4 3.4 2.0 2 0 0 2 2 2 2 G-protein alpha subunit Arf PF00025.16 ETO13745.1 - 2.5e-11 43.1 1.1 1e-05 24.8 0.0 3.4 3 0 0 3 3 3 3 ADP-ribosylation factor family Miro PF08477.8 ETO13745.1 - 5.4e-05 23.6 0.8 0.095 13.1 0.0 2.6 2 1 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 ETO13745.1 - 0.0008 18.6 7.0 0.005 16.0 0.1 2.8 3 0 0 3 3 3 2 Gtr1/RagA G protein conserved region AAA_18 PF13238.1 ETO13745.1 - 0.0016 18.7 0.4 0.0056 16.9 0.3 2.1 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 ETO13745.1 - 0.0066 15.7 0.0 0.013 14.7 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_tran PF00005.22 ETO13745.1 - 0.02 15.1 0.4 0.037 14.3 0.3 1.4 1 0 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.12 ETO13745.1 - 0.028 13.9 0.8 2.5 7.5 0.2 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Mg_chelatase PF01078.16 ETO13745.1 - 0.028 13.5 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 ETO13745.1 - 0.093 12.3 0.0 0.56 9.8 0.0 2.3 2 0 0 2 2 2 0 NACHT domain Pox_A32 PF04665.7 ETO13745.1 - 0.11 11.8 0.1 0.11 11.8 0.0 2.7 3 1 0 3 3 3 0 Poxvirus A32 protein FtsK_SpoIIIE PF01580.13 ETO13745.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA PF00004.24 ETO13745.1 - 0.15 12.3 0.4 15 5.8 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 ETO13745.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETO13745.1 - 0.16 11.9 0.1 0.23 11.4 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain Ras PF00071.17 ETO13745.1 - 0.25 10.7 2.0 28 4.0 0.0 3.5 3 1 0 3 3 3 0 Ras family PLRV_ORF5 PF01690.12 ETO13747.1 - 1 8.4 9.3 1.1 8.2 6.4 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein RR_TM4-6 PF06459.7 ETO13747.1 - 4.7 7.0 8.6 4.6 7.0 6.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Met_10 PF02475.11 ETO13749.1 - 3.1e-27 95.4 0.0 3.9e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.9 ETO13749.1 - 5.8e-06 25.7 0.0 1.1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 ETO13749.1 - 1.3e-05 24.8 0.0 1.7e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETO13749.1 - 0.00029 20.8 0.0 0.00044 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 ETO13749.1 - 0.00035 20.0 0.0 0.00059 19.2 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 tRNA_U5-meth_tr PF05958.6 ETO13749.1 - 0.00044 19.0 0.0 0.00059 18.6 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase TRM PF02005.11 ETO13749.1 - 0.0021 17.0 0.0 0.0025 16.8 0.0 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase DNA_methylase PF00145.12 ETO13749.1 - 0.003 16.7 0.1 0.013 14.6 0.0 1.8 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase RrnaAD PF00398.15 ETO13749.1 - 0.0032 16.5 0.0 0.0044 16.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.2 ETO13749.1 - 0.009 16.5 0.0 0.013 16.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TYW3 PF02676.9 ETO13750.1 - 1.4e-52 177.8 0.0 2.2e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase TYW3 TMEM51 PF15345.1 ETO13750.1 - 0.0083 15.8 3.1 0.012 15.2 0.5 2.1 2 0 0 2 2 2 1 Transmembrane protein 51 Herpes_UL55 PF04537.7 ETO13750.1 - 0.013 14.8 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL55 protein DUF2457 PF10446.4 ETO13750.1 - 0.066 11.9 6.1 0.1 11.3 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) zf-C3HC4_3 PF13920.1 ETO13751.1 - 2.1e-11 43.3 16.1 2.6e-09 36.5 7.5 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO13751.1 - 2.3e-10 40.1 15.9 1.3e-08 34.5 7.5 2.9 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.1 ETO13751.1 - 7.8e-09 35.4 12.5 7.8e-09 35.4 8.6 3.2 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO13751.1 - 1.9e-08 33.7 11.8 1.9e-08 33.7 8.2 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO13751.1 - 1.2e-07 31.3 15.1 6.3e-07 29.0 7.7 2.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 ETO13751.1 - 2.1e-05 24.2 7.0 2.1e-05 24.2 4.9 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 ETO13751.1 - 2.8e-05 23.8 13.5 3.7e-05 23.4 6.0 3.2 3 1 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 ETO13751.1 - 4e-05 23.2 3.8 4e-05 23.2 2.6 3.7 2 1 1 3 3 3 1 RING-type zinc-finger SAP PF02037.22 ETO13751.1 - 8.1e-05 22.0 0.9 0.00022 20.6 0.6 1.8 1 1 0 1 1 1 1 SAP domain zf-rbx1 PF12678.2 ETO13751.1 - 0.0047 16.9 16.9 0.01 15.9 6.2 3.2 3 1 0 3 3 2 1 RING-H2 zinc finger U-box PF04564.10 ETO13751.1 - 0.0067 16.3 0.2 0.044 13.7 0.0 2.5 2 0 0 2 2 2 1 U-box domain Prok-RING_4 PF14447.1 ETO13751.1 - 0.023 14.2 8.8 0.47 10.0 4.0 3.2 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 Sgf11 PF08209.6 ETO13751.1 - 0.054 12.8 0.3 0.054 12.8 0.2 3.3 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zinc-ribbons_6 PF07191.7 ETO13751.1 - 0.51 10.1 13.6 3.3 7.5 5.2 2.8 2 0 0 2 2 2 0 zinc-ribbons zf-Apc11 PF12861.2 ETO13751.1 - 0.56 10.0 6.2 1.4 8.7 3.2 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF329 PF03884.9 ETO13751.1 - 1.6 8.3 12.2 13 5.4 0.2 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF329) DZR PF12773.2 ETO13751.1 - 4.7 7.1 11.0 13 5.6 5.9 2.6 2 0 0 2 2 2 0 Double zinc ribbon Rad50_zn_hook PF04423.9 ETO13751.1 - 4.8 6.7 15.9 9.8 5.7 0.2 5.2 5 0 0 5 5 5 0 Rad50 zinc hook motif zf-FPG_IleRS PF06827.9 ETO13751.1 - 9.3 6.0 10.9 1.3 8.7 1.5 3.3 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS PP2C PF00481.16 ETO13752.1 - 3.7e-35 121.5 0.1 3.7e-19 69.1 0.0 2.3 2 1 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 ETO13752.1 - 5.5e-05 22.6 0.0 0.00079 18.8 0.0 2.5 2 1 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.7 ETO13752.1 - 0.022 14.4 0.0 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Band_7 PF01145.20 ETO13753.1 - 2.6e-13 50.2 9.9 2.6e-13 50.2 6.9 1.6 1 1 1 2 2 2 1 SPFH domain / Band 7 family Tissue_fac PF01108.12 ETO13753.1 - 0.092 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Tissue factor TMEM107 PF14995.1 ETO13754.1 - 0.007 16.4 0.5 0.007 16.4 0.4 2.3 1 1 0 2 2 2 1 Transmembrane protein Skp1_POZ PF03931.10 ETO13755.1 - 6.6e-06 26.1 0.2 1.7e-05 24.8 0.1 1.8 1 1 1 2 2 2 1 Skp1 family, tetramerisation domain Skp1 PF01466.14 ETO13755.1 - 7.8e-06 25.8 3.3 0.053 13.5 0.0 2.5 1 1 1 2 2 2 2 Skp1 family, dimerisation domain hNIFK_binding PF12196.3 ETO13755.1 - 0.05 12.9 1.0 0.1 11.9 0.7 1.5 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK cNMP_binding PF00027.24 ETO13757.1 - 1.3e-15 56.9 1.0 2.4e-15 56.0 0.0 2.0 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain CAF-1_p150 PF11600.3 ETO13757.1 - 2.4 7.4 21.4 3.6 6.8 14.8 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CDC27 PF09507.5 ETO13757.1 - 3.8 6.6 14.4 5.3 6.1 10.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF106 PF01956.11 ETO13758.1 - 0.53 9.7 3.3 1 8.8 0.0 2.7 3 0 0 3 3 3 0 Integral membrane protein DUF106 VIT1 PF01988.14 ETO13758.1 - 0.91 8.9 5.4 0.66 9.4 0.4 2.3 2 0 0 2 2 2 0 VIT family Nop14 PF04147.7 ETO13758.1 - 3.1 5.6 39.5 0.011 13.6 13.3 2.4 2 0 0 2 2 2 0 Nop14-like family TRAP_alpha PF03896.11 ETO13758.1 - 6.2 5.7 19.1 0.015 14.3 5.2 2.4 2 1 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Peptidase_M16_C PF05193.16 ETO13759.1 - 1.3e-27 96.6 0.0 1.6e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase M16 inactive domain ASFV_p27 PF06556.6 ETO13761.1 - 0.064 13.1 0.2 0.77 9.6 0.0 2.3 2 0 0 2 2 2 0 IAP-like protein p27 C-terminus Menin PF05053.8 ETO13762.1 - 0.38 8.8 6.3 0.39 8.8 4.4 1.1 1 0 0 1 1 1 0 Menin DUF1183 PF06682.7 ETO13762.1 - 0.54 9.8 12.7 0.68 9.4 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF2457 PF10446.4 ETO13764.1 - 0.55 8.9 23.2 0.78 8.4 16.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Menin PF05053.8 ETO13764.1 - 4.9 5.1 16.1 6.2 4.8 11.1 1.1 1 0 0 1 1 1 0 Menin DUF1116 PF06545.6 ETO13765.1 - 0.075 12.1 0.9 0.18 10.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1116) Kelch_4 PF13418.1 ETO13767.1 - 0.0025 17.5 1.9 1.1 9.0 0.0 3.1 3 0 0 3 3 3 2 Galactose oxidase, central domain 7TM_transglut PF14402.1 ETO13767.1 - 0.14 11.0 0.1 0.21 10.4 0.1 1.3 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase WD40 PF00400.27 ETO13768.1 - 2.6e-21 74.6 2.9 1.4e-09 37.4 0.9 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO13768.1 - 1.9e-06 26.3 0.5 0.00096 17.4 0.0 2.4 1 1 2 3 3 3 2 Nucleoporin Nup120/160 WD40 PF00400.27 ETO13769.1 - 7e-37 124.0 12.3 4.3e-10 39.0 0.3 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO13769.1 - 1.7e-08 33.0 0.2 0.046 11.8 0.0 3.9 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO13769.1 - 5.9e-05 21.9 8.4 0.19 10.4 3.3 3.1 1 1 2 3 3 3 3 Nup133 N terminal like BBS2_N PF14781.1 ETO13769.1 - 0.093 12.3 2.0 0.46 10.1 0.1 2.4 1 1 2 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal DUF810 PF05664.6 ETO13770.1 - 0.046 12.0 0.2 0.067 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF810) Flu_NP PF00506.13 ETO13770.1 - 0.1 11.0 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Influenza virus nucleoprotein BIR PF00653.16 ETO13771.1 - 0.015 15.7 0.3 4.2 7.8 0.0 2.4 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain Chorein_N PF12624.2 ETO13772.1 - 5.1e-05 22.7 3.1 0.00027 20.4 0.2 2.3 1 1 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF4393 PF14337.1 ETO13772.1 - 0.076 12.4 0.1 0.17 11.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4393) WD40 PF00400.27 ETO13773.1 - 6.6e-42 139.9 12.7 2.2e-10 39.9 0.3 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO13773.1 - 5.7e-05 21.4 0.4 2 6.4 0.0 4.3 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Sec23_trunk PF04811.10 ETO13773.1 - 0.1 11.9 0.1 0.28 10.5 0.0 1.8 2 0 0 2 2 2 0 Sec23/Sec24 trunk domain SR-25 PF10500.4 ETO13774.1 - 0.002 17.6 10.8 0.0032 16.9 7.5 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein RILP PF11461.3 ETO13775.1 - 0.26 11.4 1.5 0.57 10.3 0.2 2.2 1 1 1 2 2 2 0 Rab interacting lysosomal protein TMEM171 PF15471.1 ETO13775.1 - 0.6 8.8 3.1 0.88 8.2 2.1 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 Sec62 PF03839.11 ETO13775.1 - 5.4 6.3 6.3 1.6 8.1 2.3 1.6 1 1 0 1 1 1 0 Translocation protein Sec62 CopC PF04234.7 ETO13776.1 - 0.048 14.2 0.0 0.86 10.2 0.0 2.1 2 0 0 2 2 2 0 CopC domain Phytochelatin PF05023.9 ETO13777.1 - 8.1e-09 34.7 0.8 1.6e-08 33.7 0.6 1.4 1 1 0 1 1 1 1 Phytochelatin synthase Tim54 PF11711.3 ETO13777.1 - 0.073 11.6 7.7 0.033 12.8 3.7 1.4 1 1 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Sporozoite_P67 PF05642.6 ETO13777.1 - 0.16 9.7 3.8 0.23 9.2 2.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HSP90 PF00183.13 ETO13777.1 - 0.19 10.0 11.5 0.36 9.1 8.0 1.4 1 0 0 1 1 1 0 Hsp90 protein Eapp_C PF10238.4 ETO13777.1 - 0.36 10.7 9.6 0.19 11.6 2.6 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein RNase_H2-Ydr279 PF09468.5 ETO13777.1 - 0.49 9.5 10.3 0.012 14.7 2.1 1.8 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) DUF1510 PF07423.6 ETO13777.1 - 4.5 6.5 15.7 2.2 7.6 7.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Peptidase_S49_N PF08496.5 ETO13777.1 - 5.6 6.7 6.2 57 3.4 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Bap31 PF05529.7 ETO13777.1 - 5.6 6.3 10.4 25 4.2 0.1 2.2 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like PI3_PI4_kinase PF00454.22 ETO13778.1 - 1.9e-07 30.7 0.3 6e-07 29.1 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase Med3 PF11593.3 ETO13778.1 - 0.028 13.6 2.3 0.036 13.3 1.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Dicty_REP PF05086.7 ETO13778.1 - 0.028 12.1 5.9 0.044 11.5 4.1 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MAS20 PF02064.10 ETO13778.1 - 0.04 13.8 1.8 0.83 9.5 0.3 2.4 2 0 0 2 2 2 0 MAS20 protein import receptor RPAP3_C PF13877.1 ETO13778.1 - 0.065 13.2 0.5 0.16 11.9 0.1 1.8 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 SSP160 PF06933.6 ETO13778.1 - 0.076 10.9 11.7 0.098 10.6 8.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 AJAP1_PANP_C PF15298.1 ETO13778.1 - 0.1 12.4 10.4 0.15 11.8 7.2 1.2 1 0 0 1 1 1 0 AJAP1/PANP C-terminus DUF3439 PF11921.3 ETO13778.1 - 0.27 11.0 14.4 0.53 10.0 10.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 ETO13778.1 - 1 9.1 21.7 1.7 8.4 15.1 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Benyvirus_14KDa PF07255.6 ETO13779.1 - 0.0068 16.2 0.2 0.014 15.2 0.0 1.6 1 1 1 2 2 2 1 Benyvirus 14KDa protein PI3K_rbd PF00794.13 ETO13780.1 - 0.0074 16.2 0.2 0.021 14.7 0.0 1.8 1 1 0 1 1 1 1 PI3-kinase family, ras-binding domain IL4Ra_N PF09238.5 ETO13780.1 - 0.047 13.8 0.3 0.15 12.1 0.1 1.9 1 1 1 2 2 2 0 Interleukin-4 receptor alpha chain, N-terminal DUF1474 PF07342.6 ETO13780.1 - 0.16 12.1 1.0 0.27 11.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) Dicty_REP PF05086.7 ETO13782.1 - 2.2 5.9 4.0 3.3 5.3 2.8 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein IBB PF01749.15 ETO13782.1 - 8.5 6.6 12.1 0.72 10.0 4.7 1.9 2 0 0 2 2 2 0 Importin beta binding domain DUF4611 PF15387.1 ETO13783.1 - 0.16 12.1 1.0 0.24 11.5 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) TFIIF_alpha PF05793.7 ETO13783.1 - 0.27 9.5 2.0 0.31 9.3 1.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Prog_receptor PF02161.10 ETO13784.1 - 0.024 13.4 4.0 0.028 13.2 2.8 1.1 1 0 0 1 1 1 0 Progesterone receptor MIP-T3 PF10243.4 ETO13784.1 - 0.11 10.9 18.1 0.14 10.6 12.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF789 PF05623.7 ETO13784.1 - 0.33 10.3 4.6 0.49 9.8 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF789) BLVR PF06375.6 ETO13784.1 - 1.3 8.7 19.4 2.3 8.0 13.5 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Vfa1 PF08432.5 ETO13784.1 - 2 8.3 21.8 3.1 7.7 15.1 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 ETO13784.1 - 3 5.7 12.5 4 5.3 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Sec62 PF03839.11 ETO13784.1 - 4.1 6.7 15.1 6.2 6.1 10.5 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 SOBP PF15279.1 ETO13784.1 - 6.5 7.0 12.2 8.5 6.6 8.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein FAM176 PF14851.1 ETO13784.1 - 8.2 6.0 6.7 16 5.1 4.6 1.5 1 0 0 1 1 1 0 FAM176 family HET-s_218-289 PF11558.3 ETO13785.1 - 0.052 13.5 0.1 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 Het-s 218-289 DUF1951 PF09188.5 ETO13786.1 - 3.3 7.6 6.5 0.66 9.9 2.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1951) DUF3324 PF11797.3 ETO13787.1 - 0.17 11.5 0.6 3.1 7.5 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function C-terminal (DUF3324) Snapin_Pallidin PF14712.1 ETO13788.1 - 0.064 13.5 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Snapin/Pallidin WWE PF02825.15 ETO13788.1 - 0.11 11.8 0.1 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 WWE domain Adap_comp_sub PF00928.16 ETO13789.1 - 2.4e-33 115.3 0.3 5.3e-30 104.4 0.0 2.1 1 1 1 2 2 2 2 Adaptor complexes medium subunit family Pkinase PF00069.20 ETO13790.1 - 6.2e-27 94.3 0.0 2.8e-20 72.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO13790.1 - 1.5e-05 24.1 0.0 5.4e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 ETO13790.1 - 0.0039 16.2 0.2 0.0058 15.7 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO13790.1 - 0.0061 16.3 0.0 0.0096 15.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Axin_b-cat_bind PF08833.5 ETO13791.1 - 0.05 13.3 2.2 8.9 6.1 0.0 2.6 2 0 0 2 2 2 0 Axin beta-catenin binding domain Ribonuc_L-PSP PF01042.16 ETO13792.1 - 1.1e-15 57.4 0.0 2.4e-09 37.0 0.0 2.3 2 0 0 2 2 2 2 Endoribonuclease L-PSP NST1 PF13945.1 ETO13792.1 - 0.00036 20.6 4.2 0.00068 19.7 2.9 1.4 1 0 0 1 1 1 1 Salt tolerance down-regulator TFIIF_alpha PF05793.7 ETO13792.1 - 0.004 15.6 4.4 0.0052 15.2 3.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PBP1_TM PF14812.1 ETO13792.1 - 0.14 12.5 8.0 0.3 11.4 5.5 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal YL1 PF05764.8 ETO13792.1 - 0.41 10.2 11.2 0.038 13.5 4.6 1.6 2 0 0 2 2 2 0 YL1 nuclear protein ATP_bind_4 PF01902.12 ETO13793.1 - 1e-08 34.8 0.0 1.1e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 ATP-binding region DUF4293 PF14126.1 ETO13795.1 - 0.006 16.5 1.0 0.009 15.9 0.6 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4293) Conotoxin PF02950.12 ETO13795.1 - 0.69 10.7 6.0 3.4 8.5 1.4 2.5 2 0 0 2 2 2 0 Conotoxin Coiled-coil_56 PF09813.4 ETO13795.1 - 1.8 8.6 5.7 0.31 11.0 0.3 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 Peroxin-13_N PF04088.8 ETO13795.1 - 6.9 6.6 9.6 1.9 8.3 1.0 2.4 1 1 1 2 2 2 0 Peroxin 13, N-terminal region DUF2634 PF10934.3 ETO13798.1 - 0.013 15.2 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2634) DUF2585 PF10755.4 ETO13798.1 - 0.014 14.8 0.8 0.036 13.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2585) DUF2809 PF10990.3 ETO13798.1 - 0.057 13.8 0.1 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2809) DUF1980 PF09323.5 ETO13798.1 - 0.06 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF1772 PF08592.6 ETO13799.1 - 0.002 17.8 0.6 0.002 17.8 0.4 3.0 1 1 3 4 4 4 1 Domain of unknown function (DUF1772) TMEMspv1-c74-12 PF11044.3 ETO13799.1 - 0.039 13.5 0.5 0.15 11.6 0.4 2.1 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein WD40 PF00400.27 ETO13802.1 - 1.2e-13 50.3 3.0 3.9e-11 42.3 0.2 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO13802.1 - 0.068 11.2 0.2 0.35 8.9 0.0 1.8 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Trypan_PARP PF05887.6 ETO13803.1 - 0.018 14.8 0.9 0.018 14.8 0.6 4.7 4 1 1 5 5 5 0 Procyclic acidic repetitive protein (PARP) YL1 PF05764.8 ETO13805.1 - 2 7.9 47.9 0.044 13.3 25.8 2.3 2 0 0 2 2 2 0 YL1 nuclear protein C2 PF00168.25 ETO13806.1 - 2.2e-05 24.2 0.1 3.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 C2 domain Nop14 PF04147.7 ETO13807.1 - 0.00087 17.3 14.9 0.0011 16.9 10.3 1.1 1 0 0 1 1 1 1 Nop14-like family Vfa1 PF08432.5 ETO13807.1 - 0.0019 18.2 3.5 0.0019 18.2 2.4 2.3 2 0 0 2 2 2 1 AAA-ATPase Vps4-associated protein 1 RGS PF00615.14 ETO13807.1 - 0.0051 16.9 0.8 0.0051 16.9 0.6 1.8 2 0 0 2 2 2 1 Regulator of G protein signaling domain TFIIA PF03153.8 ETO13807.1 - 0.012 15.4 11.5 0.018 14.9 8.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1510 PF07423.6 ETO13807.1 - 1.1 8.6 18.6 0.043 13.1 4.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Cwf_Cwc_15 PF04889.7 ETO13807.1 - 2.5 7.7 27.2 6.8 6.3 18.9 1.6 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 ETO13807.1 - 3.5 5.5 18.6 0.12 10.4 6.3 2.0 2 0 0 2 2 2 0 CDC45-like protein RasGAP PF00616.14 ETO13811.1 - 0.00054 19.6 3.4 0.00063 19.4 2.3 1.2 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase Eapp_C PF10238.4 ETO13811.1 - 0.049 13.5 9.6 0.064 13.1 6.7 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein Secretin_N_2 PF07655.8 ETO13811.1 - 0.07 13.5 11.4 0.081 13.3 7.9 1.1 1 0 0 1 1 1 0 Secretin N-terminal domain Rad60-SLD PF11976.3 ETO13811.1 - 0.11 12.2 0.1 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Apis_Csd PF11671.3 ETO13811.1 - 0.23 11.2 12.9 0.26 11.0 9.0 1.2 1 0 0 1 1 1 0 Complementary sex determiner protein KilA-N PF04383.8 ETO13811.1 - 0.53 9.9 9.4 0.85 9.2 6.5 1.4 1 1 0 1 1 1 0 KilA-N domain PGP_phosphatase PF09419.5 ETO13812.1 - 0.0001 21.7 0.2 0.00018 20.9 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase PUB PF09409.5 ETO13814.1 - 6.8e-07 28.9 0.8 1.5e-06 27.8 0.6 1.6 1 0 0 1 1 1 1 PUB domain Glycophorin_A PF01102.13 ETO13814.1 - 0.026 14.2 0.2 0.052 13.3 0.1 1.4 1 0 0 1 1 1 0 Glycophorin A Peptidase_C39_2 PF13529.1 ETO13815.1 - 4e-09 36.9 1.0 0.00023 21.5 0.0 2.4 2 1 0 2 2 2 2 Peptidase_C39 like family BRK PF07533.11 ETO13815.1 - 0.11 11.9 0.4 7.5 6.1 0.0 2.4 2 0 0 2 2 2 0 BRK domain UQ_con PF00179.21 ETO13816.1 - 2.2e-22 78.9 0.0 2.9e-21 75.3 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme CCSMST1 PF15013.1 ETO13816.1 - 0.00097 19.0 1.3 0.28 11.1 0.1 2.4 2 0 0 2 2 2 2 CCSMST1 family DUF2457 PF10446.4 ETO13817.1 - 0.012 14.3 14.6 0.021 13.5 10.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 ETO13817.1 - 0.15 9.9 23.6 0.22 9.4 16.3 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 ETO13817.1 - 2.5 7.2 23.4 4.3 6.5 16.2 1.3 1 0 0 1 1 1 0 SDA1 Totivirus_coat PF05518.6 ETO13817.1 - 3.8 5.2 6.6 6.7 4.4 4.6 1.4 1 0 0 1 1 1 0 Totivirus coat protein DNA_pol_phi PF04931.8 ETO13817.1 - 8.9 3.9 21.0 13 3.4 14.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi Nucleoplasmin PF03066.10 ETO13819.1 - 0.0011 18.4 1.4 0.0018 17.8 0.9 1.2 1 0 0 1 1 1 1 Nucleoplasmin PBP1_TM PF14812.1 ETO13819.1 - 0.011 16.0 7.6 0.024 14.9 5.3 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nab6_mRNP_bdg PF10567.4 ETO13819.1 - 0.041 12.8 0.9 0.79 8.6 0.1 2.1 2 0 0 2 2 2 0 RNA-recognition motif Sporozoite_P67 PF05642.6 ETO13819.1 - 0.071 10.9 0.8 0.091 10.6 0.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sigma70_ner PF04546.8 ETO13819.1 - 0.17 11.4 5.0 0.28 10.7 3.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 ETO13819.1 - 0.29 9.1 4.6 0.41 8.6 3.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Chordopox_A13L PF05961.6 ETO13820.1 - 0.0088 15.9 0.2 0.03 14.2 0.0 1.9 2 1 1 3 3 3 1 Chordopoxvirus A13L protein InvH PF04741.7 ETO13820.1 - 0.02 14.7 0.1 0.035 13.9 0.1 1.4 1 0 0 1 1 1 0 InvH outer membrane lipoprotein DUF3584 PF12128.3 ETO13822.1 - 0.00064 17.2 13.5 0.00085 16.8 9.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF869 PF05911.6 ETO13822.1 - 0.0056 14.9 14.7 0.0065 14.7 10.2 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) Reo_sigmaC PF04582.7 ETO13822.1 - 0.021 14.0 2.0 0.043 12.9 0.7 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Fusion_gly PF00523.13 ETO13822.1 - 0.029 12.4 0.2 0.041 11.9 0.2 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 Laminin_II PF06009.7 ETO13822.1 - 0.066 12.9 10.8 0.082 12.6 2.0 2.5 1 1 1 2 2 2 0 Laminin Domain II AAA_13 PF13166.1 ETO13822.1 - 0.077 11.4 12.7 0.11 10.9 8.8 1.2 1 0 0 1 1 1 0 AAA domain DUF4349 PF14257.1 ETO13822.1 - 0.1 11.7 4.6 0.036 13.2 1.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) V_ATPase_I PF01496.14 ETO13822.1 - 0.13 10.0 10.6 0.17 9.7 7.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.5 ETO13822.1 - 0.22 11.6 15.8 1.6 8.8 4.3 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family LMP PF04778.7 ETO13822.1 - 0.43 10.3 8.4 0.72 9.5 5.8 1.4 1 0 0 1 1 1 0 LMP repeated region Baculo_PEP_C PF04513.7 ETO13822.1 - 0.77 9.5 6.0 9.6 6.0 3.6 2.8 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ACR_tran PF00873.14 ETO13822.1 - 0.78 7.0 2.8 0.85 6.9 1.9 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family UBN_AB PF14075.1 ETO13822.1 - 0.93 9.1 12.8 1.2 8.7 8.2 1.6 1 1 0 1 1 1 0 Ubinuclein conserved middle domain TBPIP PF07106.8 ETO13822.1 - 1.8 8.0 19.2 0.65 9.5 4.3 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 ETO13822.1 - 1.8 8.0 22.6 1.2e+02 2.2 15.7 2.3 1 1 0 1 1 1 0 IncA protein hDGE_amylase PF14701.1 ETO13822.1 - 2.1 7.1 9.5 2.8 6.7 6.6 1.1 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Atg14 PF10186.4 ETO13822.1 - 2.2 7.1 14.3 0.33 9.8 6.8 1.7 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SlyX PF04102.7 ETO13822.1 - 2.3 8.6 12.2 0.083 13.2 1.5 3.1 2 1 0 2 2 2 0 SlyX DUF3552 PF12072.3 ETO13822.1 - 2.3 7.3 20.8 1.2 8.3 12.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF1664 PF07889.7 ETO13822.1 - 2.5 7.9 11.3 1.4 8.7 2.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TrbI_Ftype PF09677.5 ETO13822.1 - 2.5 7.9 5.5 1.2 8.9 0.5 2.6 1 1 2 3 3 3 0 Type-F conjugative transfer system protein (TrbI_Ftype) KLRAQ PF10205.4 ETO13822.1 - 3.4 7.7 17.9 0.66 10.0 2.1 3.0 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein Surf_Ag_VNR PF07244.10 ETO13822.1 - 3.4 8.1 4.9 15 6.1 0.1 2.8 3 1 0 3 3 2 0 Surface antigen variable number repeat Tropomyosin_1 PF12718.2 ETO13822.1 - 4.9 7.0 21.3 7.3 6.4 14.3 1.5 1 1 0 1 1 1 0 Tropomyosin like PEARLI-4 PF05278.7 ETO13822.1 - 4.9 6.4 16.6 0.84 8.9 3.8 2.4 1 1 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF4404 PF14357.1 ETO13822.1 - 5.2 7.5 16.1 1.1 9.6 0.3 3.4 1 1 1 3 3 3 0 Domain of unknown function (DUF4404) ERM PF00769.14 ETO13822.1 - 7.7 5.9 27.3 0.51 9.8 5.5 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Ribosomal_L44 PF00935.14 ETO13824.1 - 6.3e-27 93.4 10.9 6.3e-27 93.4 7.5 2.1 2 1 1 3 3 3 1 Ribosomal protein L44 CytoC_RC PF02276.13 ETO13824.1 - 0.0084 15.2 0.3 0.0093 15.1 0.2 1.1 1 0 0 1 1 1 1 Photosynthetic reaction centre cytochrome C subunit zf-CHY PF05495.7 ETO13824.1 - 0.054 13.6 2.4 0.35 11.0 0.1 2.2 2 0 0 2 2 2 0 CHY zinc finger zinc-ribbons_6 PF07191.7 ETO13824.1 - 0.16 11.7 4.8 2.4 8.0 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbons TMEM237 PF15383.1 ETO13824.1 - 0.18 10.8 0.8 0.22 10.6 0.6 1.2 1 0 0 1 1 1 0 Transmembrane protein 237 Cytochrome_C7 PF14522.1 ETO13824.1 - 0.19 11.3 7.3 3.2 7.4 5.0 2.2 1 1 0 1 1 1 0 Cytochrome c7 Cytochrome_C554 PF13435.1 ETO13824.1 - 0.22 11.5 7.1 0.75 9.8 4.2 1.9 1 1 0 1 1 1 0 Cytochrome c554 and c-prime Cytochrom_c3_2 PF14537.1 ETO13824.1 - 5.4 7.4 11.0 54 4.2 7.6 2.0 1 1 0 1 1 1 0 Cytochrome c3 zf-BED PF02892.10 ETO13824.1 - 5.8 6.7 10.6 0.49 10.1 1.8 2.4 2 1 0 2 2 2 0 BED zinc finger PLU-1 PF08429.6 ETO13825.1 - 0.078 11.8 0.2 0.099 11.5 0.2 1.0 1 0 0 1 1 1 0 PLU-1-like protein PPP1R35_C PF15503.1 ETO13825.1 - 0.74 9.3 3.8 1.6 8.2 2.7 1.5 1 1 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 35 C-terminus PPP4R2 PF09184.6 ETO13826.1 - 0.0099 15.4 11.2 0.012 15.1 7.8 1.2 1 0 0 1 1 1 1 PPP4R2 SDA1 PF05285.7 ETO13826.1 - 0.033 13.4 20.3 0.046 13.0 14.1 1.1 1 0 0 1 1 1 0 SDA1 Vfa1 PF08432.5 ETO13826.1 - 0.18 11.8 11.1 0.34 10.9 7.7 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Sporozoite_P67 PF05642.6 ETO13826.1 - 0.25 9.1 12.1 0.38 8.5 8.4 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CENP-T PF15511.1 ETO13826.1 - 1.5 8.0 10.3 2.1 7.5 7.2 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CDC45 PF02724.9 ETO13826.1 - 2.7 5.9 15.4 4.6 5.1 10.6 1.3 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 ETO13826.1 - 4.8 6.3 13.7 7.3 5.7 9.5 1.2 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.4 ETO13826.1 - 9 4.9 18.4 12 4.4 12.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ribosomal_60s PF00428.14 ETO13828.1 - 0.007 16.7 4.1 0.007 16.7 2.8 2.8 3 0 0 3 3 3 1 60s Acidic ribosomal protein HAUS6_N PF14661.1 ETO13828.1 - 0.0094 15.3 2.8 0.0094 15.3 1.9 2.4 2 1 1 3 3 3 1 HAUS augmin-like complex subunit 6 N-terminus LMBR1 PF04791.11 ETO13829.1 - 0.0092 14.6 2.9 0.013 14.0 2.0 1.3 1 0 0 1 1 1 1 LMBR1-like membrane protein V_ATPase_I PF01496.14 ETO13829.1 - 0.027 12.3 8.7 0.031 12.1 6.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HrpB7 PF09486.5 ETO13829.1 - 0.027 14.3 1.0 0.027 14.3 0.7 2.1 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Reo_sigmaC PF04582.7 ETO13829.1 - 0.03 13.5 2.5 0.037 13.1 1.7 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein bZIP_1 PF00170.16 ETO13829.1 - 0.2 11.6 8.5 0.28 11.1 4.4 2.4 1 1 1 2 2 2 0 bZIP transcription factor Asp-B-Hydro_N PF05279.6 ETO13829.1 - 0.83 9.4 9.5 1.4 8.6 6.6 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region NCKAP5 PF15246.1 ETO13829.1 - 0.98 8.7 18.8 1.7 7.9 13.1 1.4 1 1 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein DUF2203 PF09969.4 ETO13829.1 - 2.2 8.5 13.7 0.036 14.2 1.9 2.7 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) HAUS6_N PF14661.1 ETO13829.1 - 2.8 7.2 15.3 4.9 6.4 10.4 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Atg14 PF10186.4 ETO13829.1 - 3.6 6.4 17.1 5.1 5.9 11.8 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF972 PF06156.8 ETO13829.1 - 4 7.8 19.4 0.24 11.7 9.1 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF972) IncA PF04156.9 ETO13829.1 - 5.9 6.4 17.6 18 4.8 12.2 1.7 1 1 0 1 1 1 0 IncA protein Exo_endo_phos_2 PF14529.1 ETO13830.1 - 0.01 15.4 1.1 0.017 14.7 0.1 2.0 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase DUF1182 PF06681.8 ETO13830.1 - 0.029 13.5 1.4 0.053 12.7 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1182) CHU_C PF13585.1 ETO13830.1 - 3.3 7.6 8.2 0.55 10.1 1.0 2.8 2 1 0 3 3 3 0 C-terminal domain of CHU protein family DUF1642 PF07852.6 ETO13831.1 - 0.026 14.8 0.0 0.036 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1642) Peptidase_C30 PF05409.8 ETO13832.1 - 0.082 11.9 0.1 0.09 11.8 0.0 1.1 1 0 0 1 1 1 0 Coronavirus endopeptidase C30 DUF3682 PF12446.3 ETO13832.1 - 0.58 10.4 4.5 1 9.6 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) CENP-B_dimeris PF09026.5 ETO13833.1 - 0.076 13.2 6.3 1.2 9.4 1.2 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Mucin PF01456.12 ETO13833.1 - 0.6 9.8 46.9 0.18 11.5 20.7 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein CDC27 PF09507.5 ETO13833.1 - 7.1 5.7 61.0 1.8 7.7 19.9 2.3 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 MAT1 PF06391.8 ETO13834.1 - 0.0079 15.8 5.8 0.01 15.3 4.0 1.3 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 WD40 PF00400.27 ETO13835.1 - 0.024 14.5 0.2 1.2 9.1 0.1 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat WD40 PF00400.27 ETO13836.1 - 2.3e-27 93.8 11.4 6.2e-07 29.0 0.0 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 ETO13836.1 - 1.5e-06 28.1 4.2 0.023 14.4 0.0 3.3 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 ETO13836.1 - 0.00015 21.1 0.4 0.19 11.2 0.0 4.2 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PKD_channel PF08016.7 ETO13837.1 - 3.7e-34 117.9 15.0 4.6e-34 117.5 10.4 1.1 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 ETO13837.1 - 1.1e-10 41.0 25.3 1.1e-10 41.0 17.5 1.6 2 0 0 2 2 2 1 Ion transport protein EF-hand_1 PF00036.27 ETO13837.1 - 4.3e-07 28.7 0.1 0.051 12.9 0.0 3.0 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 ETO13837.1 - 7.1e-07 28.2 0.4 0.0036 16.5 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 ETO13837.1 - 2.1e-05 24.5 0.1 0.077 13.1 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 ETO13837.1 - 0.00041 19.8 0.3 0.011 15.3 0.0 2.5 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO13837.1 - 0.00055 19.5 5.6 0.27 11.2 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.4 ETO13837.1 - 0.0061 16.5 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region DUF843 PF05814.6 ETO13837.1 - 0.04 13.7 3.5 3.3 7.5 0.1 3.3 3 0 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) RepA1_leader PF08048.7 ETO13837.1 - 2.5 8.2 4.7 0.64 10.1 0.4 2.1 2 0 0 2 2 2 0 Tap RepA1 leader peptide Steroid_dh PF02544.11 ETO13839.1 - 2.7e-27 95.3 0.2 5.4e-27 94.4 0.1 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 ETO13839.1 - 4e-05 23.6 1.1 0.00012 22.1 0.8 1.8 1 0 0 1 1 1 1 Phospholipid methyltransferase Pkinase PF00069.20 ETO13840.1 - 2.1e-07 30.3 0.1 5.6e-07 28.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain DUF739 PF05339.6 ETO13840.1 - 0.0022 17.7 0.2 0.0027 17.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF739) Topoisom_I_N PF02919.10 ETO13840.1 - 0.0031 16.8 1.3 0.0039 16.5 0.9 1.2 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, DNA binding fragment DUF515 PF04415.7 ETO13840.1 - 0.0042 15.3 1.1 0.0051 15.1 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF515) Pkinase_Tyr PF07714.12 ETO13840.1 - 0.025 13.6 0.0 0.041 12.9 0.0 1.3 1 1 0 1 1 1 0 Protein tyrosine kinase FliD_N PF02465.13 ETO13840.1 - 0.028 14.7 0.4 0.038 14.3 0.3 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus BLOC1_2 PF10046.4 ETO13840.1 - 0.29 11.2 2.6 0.44 10.7 1.8 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cytochrom_C1 PF02167.10 ETO13841.1 - 0.75 9.3 4.0 0.18 11.4 0.2 1.9 2 0 0 2 2 2 0 Cytochrome C1 family Med15 PF09606.5 ETO13842.1 - 2.4e-05 22.7 29.0 2.4e-05 22.7 20.1 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1777 PF08648.7 ETO13842.1 - 0.00059 19.6 33.2 0.00059 19.6 23.0 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1777) Ndc1_Nup PF09531.5 ETO13842.1 - 5.1 5.3 17.0 4.9 5.4 11.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Nucleoplasmin PF03066.10 ETO13843.1 - 0.089 12.2 0.6 0.14 11.6 0.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin PP2C PF00481.16 ETO13844.1 - 1.6e-22 80.1 0.0 3.4e-22 79.0 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 ETO13844.1 - 0.0072 16.0 0.0 1 9.0 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) WD40 PF00400.27 ETO13845.1 - 1.8e-64 211.4 15.0 1.7e-12 46.6 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Kelch_4 PF13418.1 ETO13845.1 - 0.00052 19.7 0.0 0.0015 18.2 0.0 1.9 1 0 0 1 1 1 1 Galactose oxidase, central domain DUF1652 PF07865.6 ETO13845.1 - 0.00089 18.8 0.0 0.064 12.8 0.0 3.5 4 0 0 4 4 4 1 Protein of unknown function (DUF1652) Spore_III_AF PF09581.5 ETO13845.1 - 0.0017 18.2 0.3 0.0028 17.5 0.2 1.4 1 0 0 1 1 1 1 Stage III sporulation protein AF (Spore_III_AF) Nup160 PF11715.3 ETO13845.1 - 0.0029 15.8 6.7 2.1 6.3 0.2 4.9 2 2 1 4 4 4 2 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO13845.1 - 0.0088 16.1 0.0 0.037 14.2 0.0 2.1 1 0 0 1 1 1 1 Kelch motif Resistin PF06954.6 ETO13845.1 - 0.05 13.8 0.0 5.8 7.2 0.1 2.8 2 1 0 2 2 2 0 Resistin PD40 PF07676.7 ETO13845.1 - 1.7 8.3 7.1 55 3.5 0.0 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Kelch_6 PF13964.1 ETO13846.1 - 0.051 13.7 0.2 0.2 11.8 0.0 2.1 2 0 0 2 2 2 0 Kelch motif Sad1_UNC PF07738.8 ETO13847.1 - 0.00064 19.5 0.2 0.0015 18.3 0.0 1.6 1 1 1 2 2 2 1 Sad1 / UNC-like C-terminal DSS1_SEM1 PF05160.8 ETO13847.1 - 0.034 13.9 2.9 0.034 13.9 2.0 2.0 2 0 0 2 2 2 0 DSS1/SEM1 family IFRD PF05004.8 ETO13847.1 - 0.089 11.8 1.7 0.1 11.6 1.2 1.1 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) CDC45 PF02724.9 ETO13848.1 - 0.013 13.5 1.5 0.013 13.6 1.0 1.2 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.12 ETO13848.1 - 0.022 14.5 0.6 0.022 14.5 0.4 1.2 1 0 0 1 1 1 0 DDHD domain Vfa1 PF08432.5 ETO13848.1 - 0.025 14.6 8.4 0.041 13.9 5.8 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RR_TM4-6 PF06459.7 ETO13848.1 - 0.088 12.6 6.3 0.13 12.1 4.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Packaging_FI PF14000.1 ETO13848.1 - 0.12 12.5 5.1 1.4 9.1 3.6 2.1 1 1 0 1 1 1 0 DNA packaging protein FI VSG_B PF13206.1 ETO13848.1 - 0.14 11.2 3.1 0.19 10.7 2.1 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain PVL_ORF50 PF07768.6 ETO13848.1 - 0.15 12.0 7.9 0.25 11.3 5.5 1.3 1 0 0 1 1 1 0 PVL ORF-50-like family Med19 PF10278.4 ETO13848.1 - 0.16 11.6 10.5 0.27 10.8 7.3 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF4519 PF15012.1 ETO13848.1 - 0.52 10.2 9.5 1.3 9.0 6.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Peptidase_S49_N PF08496.5 ETO13848.1 - 1 9.1 4.8 2.1 8.1 3.3 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal V_ATPase_I PF01496.14 ETO13848.1 - 3 5.6 8.0 4.7 4.9 5.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF912 PF06024.7 ETO13848.1 - 4 7.5 6.8 0.55 10.3 0.8 2.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) YqfQ PF14181.1 ETO13848.1 - 6.1 6.8 10.6 9.9 6.1 7.3 1.2 1 0 0 1 1 1 0 YqfQ-like protein MFS_2 PF13347.1 ETO13849.1 - 0.0071 14.7 6.4 0.0094 14.3 4.4 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein RP-C_C PF11800.3 ETO13850.1 - 0.46 10.1 2.7 0.64 9.6 1.9 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region PglZ PF08665.7 ETO13851.1 - 0.65 9.6 4.4 1.2 8.7 3.0 1.5 1 0 0 1 1 1 0 PglZ domain CytochromB561_N PF09786.4 ETO13851.1 - 2.2 6.6 12.7 2.9 6.2 8.8 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal EF-hand_1 PF00036.27 ETO13852.1 - 6.7e-08 31.3 0.1 3.4e-06 25.9 0.1 2.5 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 ETO13852.1 - 4.3e-07 29.9 0.2 0.00042 20.3 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 ETO13852.1 - 1.1e-05 24.9 0.4 0.0019 17.7 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO13852.1 - 1.7e-05 24.2 0.5 0.00087 18.9 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 ETO13852.1 - 0.0024 17.1 0.4 0.0067 15.7 0.3 1.8 1 0 0 1 1 1 1 EF hand SPARC_Ca_bdg PF10591.4 ETO13852.1 - 0.2 11.7 7.3 1 9.4 0.0 3.6 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region FAM176 PF14851.1 ETO13852.1 - 6.4 6.4 12.2 0.81 9.3 3.4 2.6 2 0 0 2 2 2 0 FAM176 family adh_short_C2 PF13561.1 ETO13853.1 - 6.1e-31 108.0 0.2 7.6e-31 107.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETO13853.1 - 3.5e-20 72.5 0.0 4.7e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETO13853.1 - 4.8e-07 29.6 0.0 7.1e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Spindle_Spc25 PF08234.7 ETO13853.1 - 0.015 15.3 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 Chromosome segregation protein Spc25 Ras PF00071.17 ETO13853.1 - 0.048 13.0 0.8 0.085 12.2 0.6 1.4 1 0 0 1 1 1 0 Ras family IMS PF00817.15 ETO13853.1 - 0.053 13.3 0.3 0.073 12.8 0.2 1.5 1 1 0 1 1 1 0 impB/mucB/samB family 3HCDH_N PF02737.13 ETO13853.1 - 0.055 13.1 0.3 0.13 11.8 0.2 1.7 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 ETO13853.1 - 0.074 11.9 2.0 0.12 11.2 1.4 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF2313 PF10076.4 ETO13853.1 - 0.077 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2313) 2-Hacid_dh_C PF02826.14 ETO13853.1 - 0.1 11.7 0.5 0.19 10.8 0.2 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Stap_Strp_toxin PF01123.15 ETO13853.1 - 1.9 9.0 5.5 3.8 8.0 3.5 1.8 1 1 0 1 1 1 0 Staphylococcal/Streptococcal toxin, OB-fold domain tRNA_edit PF04073.10 ETO13854.1 - 3.9e-09 36.4 0.0 1.3e-08 34.7 0.0 1.8 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain DUF382 PF04037.8 ETO13854.1 - 0.18 11.5 2.6 0.47 10.2 1.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF382) FadA PF09403.5 ETO13854.1 - 0.25 11.3 4.1 0.46 10.4 2.9 1.4 1 0 0 1 1 1 0 Adhesion protein FadA Ribosomal_S5_C PF03719.10 ETO13855.1 - 1.1e-23 82.3 0.1 1.8e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 ETO13855.1 - 1.4e-23 82.4 0.3 2.7e-23 81.5 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Pkinase PF00069.20 ETO13856.1 - 1.4e-106 355.3 0.1 3.6e-54 183.6 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO13856.1 - 5.1e-49 166.6 0.3 3.7e-25 88.4 0.0 3.5 3 1 0 3 3 3 3 Protein tyrosine kinase EF-hand_1 PF00036.27 ETO13856.1 - 1.8e-25 86.2 10.3 2.2e-06 26.5 0.0 4.8 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 ETO13856.1 - 8.9e-21 73.8 7.7 3.4e-10 39.9 1.3 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO13856.1 - 1.9e-18 64.6 9.1 2.6e-06 26.8 0.0 5.2 5 0 0 5 5 4 4 EF-hand domain EF-hand_8 PF13833.1 ETO13856.1 - 1.1e-16 60.1 9.2 0.0021 17.6 0.0 5.3 4 1 1 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.1 ETO13856.1 - 9.2e-16 56.3 9.6 9.1e-07 27.9 0.0 4.7 4 0 0 4 4 4 4 EF hand SPARC_Ca_bdg PF10591.4 ETO13856.1 - 3.5e-08 33.4 0.4 0.00074 19.5 0.1 3.9 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region APH PF01636.18 ETO13856.1 - 1.6e-07 31.3 0.0 0.048 13.3 0.0 3.3 3 0 0 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 ETO13856.1 - 3.4e-06 26.2 0.4 0.00073 18.6 0.0 2.8 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETO13856.1 - 8.4e-06 24.9 0.0 0.18 10.7 0.0 3.4 2 1 0 2 2 2 2 Kinase-like Mad3_BUB1_I PF08311.7 ETO13856.1 - 3.4e-05 23.6 0.1 3.4e-05 23.6 0.0 2.7 3 0 0 3 3 3 1 Mad3/BUB1 homology region 1 RIO1 PF01163.17 ETO13856.1 - 4.6e-05 22.8 1.3 0.014 14.7 0.1 2.9 2 1 0 2 2 2 1 RIO1 family YrbL-PhoP_reg PF10707.4 ETO13856.1 - 0.00012 21.4 0.1 0.00095 18.5 0.0 2.4 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL DUF2680 PF10925.3 ETO13856.1 - 0.0032 17.2 1.8 0.0071 16.1 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2680) ASFV_J13L PF05568.6 ETO13856.1 - 0.034 13.6 6.5 0.064 12.7 4.5 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein Mucin PF01456.12 ETO13856.1 - 0.14 11.9 16.2 0.28 10.9 11.2 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.3 ETO13856.1 - 0.27 11.0 6.8 0.63 9.7 4.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) EF-hand_4 PF12763.2 ETO13856.1 - 1.4 8.7 11.8 32 4.3 0.7 5.0 3 1 1 5 5 5 0 Cytoskeletal-regulatory complex EF hand FHIPEP PF00771.15 ETO13857.1 - 0.012 14.0 0.3 0.012 14.0 0.2 2.5 1 1 1 2 2 2 0 FHIPEP family DUF572 PF04502.8 ETO13857.1 - 2.9 7.0 54.3 2.4 7.3 30.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) SID-1_RNA_chan PF13965.1 ETO13857.1 - 6.5 4.7 19.6 0.88 7.6 10.4 1.7 1 1 1 2 2 2 0 dsRNA-gated channel SID-1 Mucin PF01456.12 ETO13859.1 - 0.0033 17.2 21.8 0.0033 17.2 15.1 1.9 2 0 0 2 2 2 1 Mucin-like glycoprotein DUF3439 PF11921.3 ETO13859.1 - 0.12 12.1 15.6 0.23 11.2 10.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Herpes_UL74 PF07982.7 ETO13859.1 - 2.1 6.9 12.8 3.1 6.3 8.9 1.2 1 0 0 1 1 1 0 Herpes UL74 glycoproteins SPC25 PF06703.6 ETO13860.1 - 2 7.9 6.3 4.7 6.7 4.4 1.8 1 1 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) PrgI PF12666.2 ETO13860.1 - 6.1 7.0 6.6 2.1 8.5 0.1 2.1 2 0 0 2 2 2 0 PrgI family protein PARP PF00644.15 ETO13861.1 - 9.1e-06 25.2 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain RNA_pol_Rpb1_1 PF04997.7 ETO13861.1 - 0.00016 21.0 0.0 0.00024 20.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 Pox_Ag35 PF03286.9 ETO13862.1 - 0.025 14.1 15.1 0.035 13.6 10.4 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Hid1 PF12722.2 ETO13862.1 - 0.04 11.6 8.4 0.043 11.4 5.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2457 PF10446.4 ETO13862.1 - 0.07 11.8 24.6 0.092 11.4 17.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 ETO13862.1 - 0.23 9.4 17.3 0.3 9.0 12.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 ETO13862.1 - 0.41 9.0 22.7 0.52 8.7 15.7 1.0 1 0 0 1 1 1 0 Daxx Family RRN3 PF05327.6 ETO13862.1 - 0.53 8.3 13.4 0.66 8.0 9.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sporozoite_P67 PF05642.6 ETO13862.1 - 0.54 8.0 11.7 0.84 7.4 8.1 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen POX PF07526.6 ETO13862.1 - 0.78 9.9 4.1 1.4 9.1 2.9 1.5 1 0 0 1 1 1 0 Associated with HOX SDA1 PF05285.7 ETO13862.1 - 1.9 7.6 20.2 2.4 7.3 14.0 1.1 1 0 0 1 1 1 0 SDA1 DUF1510 PF07423.6 ETO13862.1 - 2.2 7.6 19.2 3.3 7.0 13.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF1754 PF08555.5 ETO13862.1 - 9.9 6.8 15.6 19 5.9 10.8 1.4 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) DUF2457 PF10446.4 ETO13865.1 - 0.023 13.4 23.9 0.034 12.8 16.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 ETO13865.1 - 0.06 11.3 20.9 0.065 11.2 14.5 1.1 1 0 0 1 1 1 0 CDC45-like protein CENP-T PF15511.1 ETO13865.1 - 0.46 9.6 15.7 0.54 9.4 10.9 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Parvo_coat PF00740.13 ETO13865.1 - 1.1 8.1 10.0 1.2 8.0 6.9 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Nop14 PF04147.7 ETO13865.1 - 1.4 6.7 30.3 1.6 6.5 21.0 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 ETO13865.1 - 2.2 7.5 29.6 3.3 7.0 20.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Daxx PF03344.10 ETO13865.1 - 2.9 6.2 24.5 3.1 6.1 17.0 1.0 1 0 0 1 1 1 0 Daxx Family DUF2146 PF10220.4 ETO13865.1 - 3.1 5.6 15.9 3.4 5.5 11.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) SAPS PF04499.10 ETO13865.1 - 3.3 6.2 14.8 3.7 6.0 10.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Band_3_cyto PF07565.8 ETO13865.1 - 6.3 6.2 9.5 8.6 5.7 6.6 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain POP1 PF06978.6 ETO13865.1 - 9 5.9 20.7 26 4.4 14.4 1.7 1 1 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 Presenilin PF01080.12 ETO13865.1 - 9 4.9 8.9 11 4.7 6.1 1.2 1 0 0 1 1 1 0 Presenilin AAA_12 PF13087.1 ETO13866.1 - 3e-45 154.0 0.9 3e-45 154.0 0.6 1.9 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.1 ETO13866.1 - 1.4e-34 119.7 0.0 4.4e-34 118.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 ETO13866.1 - 3.6e-06 26.6 0.0 0.0024 17.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 ETO13866.1 - 4.1e-06 26.4 0.0 5.9e-05 22.7 0.0 2.4 2 1 0 2 2 2 1 Part of AAA domain ResIII PF04851.10 ETO13866.1 - 0.00015 21.6 0.5 0.0012 18.6 0.1 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 ETO13866.1 - 0.0053 16.3 2.7 2 7.8 0.0 3.9 3 1 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PIF1 PF05970.9 ETO13866.1 - 0.0092 14.9 2.1 0.087 11.7 1.0 2.4 2 1 0 2 2 2 1 PIF1-like helicase AAA_22 PF13401.1 ETO13866.1 - 0.0096 16.0 1.0 0.54 10.4 0.1 2.8 3 1 0 3 3 3 1 AAA domain DUF2075 PF09848.4 ETO13866.1 - 0.011 14.7 0.3 0.15 11.0 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 ETO13866.1 - 0.012 15.7 1.3 0.049 13.8 0.4 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 ETO13866.1 - 0.056 12.6 0.0 0.14 11.3 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.1 ETO13866.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain CAP_GLY PF01302.20 ETO13867.1 - 3e-06 26.8 0.0 5.6e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain Diphthamide_syn PF01866.12 ETO13869.1 - 5.3e-11 42.3 0.2 4.6e-06 26.0 0.0 2.5 3 0 0 3 3 3 2 Putative diphthamide synthesis protein Diphthamide_syn PF01866.12 ETO13870.1 - 1.6e-12 47.2 2.3 5.3e-12 45.5 1.6 1.7 1 1 0 1 1 1 1 Putative diphthamide synthesis protein Ribosomal_L19e PF01280.15 ETO13871.1 - 1.2e-12 47.8 5.3 1.2e-12 47.8 3.7 2.4 2 1 0 2 2 2 1 Ribosomal protein L19e RR_TM4-6 PF06459.7 ETO13871.1 - 2.2 8.1 15.5 2.7 7.7 10.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CT47 PF15623.1 ETO13871.1 - 2.7 7.6 16.3 2.9 7.5 11.3 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 GAGA_bind PF06217.7 ETO13871.1 - 5.3 6.9 12.0 7.7 6.3 8.3 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family SAPS PF04499.10 ETO13871.1 - 6.6 5.2 13.3 8.4 4.9 9.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Phage_int_SAM_3 PF14659.1 ETO13873.1 - 0.047 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain EIF_2_alpha PF07541.7 ETO13874.1 - 4.6e-18 65.0 9.3 2.1e-17 62.8 2.7 3.5 2 1 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 ETO13874.1 - 8.3e-08 32.2 0.0 8.3e-08 32.2 0.0 1.8 2 0 0 2 2 2 1 S1 RNA binding domain TFIIA PF03153.8 ETO13875.1 - 1.4 8.6 22.7 1.8 8.3 15.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.27 ETO13876.1 - 3.7e-68 223.1 13.3 1.6e-11 43.5 0.8 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO13876.1 - 2.5e-10 39.1 5.5 0.021 12.9 0.2 5.0 1 1 4 5 5 5 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO13876.1 - 2.2e-06 26.2 0.3 0.22 9.7 0.0 3.4 3 1 0 3 3 3 3 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO13876.1 - 8.2e-05 22.1 0.7 0.029 13.8 0.0 3.0 1 1 1 2 2 2 2 PQQ-like domain Nbas_N PF15492.1 ETO13876.1 - 0.0001 21.5 2.0 1.1 8.3 0.1 4.0 1 1 3 5 5 5 2 Neuroblastoma-amplified sequence, N terminal DUF3601 PF12208.3 ETO13876.1 - 0.0011 18.8 0.0 2.6 8.0 0.0 4.0 2 2 3 5 5 5 1 Domain of unknown function (DUF3601) Nucleoporin_N PF08801.6 ETO13876.1 - 0.0012 17.6 6.8 0.36 9.5 0.3 4.1 1 1 0 2 2 2 2 Nup133 N terminal like DUF1652 PF07865.6 ETO13876.1 - 0.0025 17.3 0.1 22 4.7 0.0 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF1652) Coatomer_WDAD PF04053.9 ETO13876.1 - 0.0071 15.1 0.2 0.13 11.0 0.0 2.5 2 1 1 3 3 3 1 Coatomer WD associated region PD40 PF07676.7 ETO13876.1 - 0.014 15.0 6.3 8.3 6.2 0.1 4.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO13876.1 - 0.015 15.5 0.3 1.1 9.5 0.0 3.5 2 1 1 4 4 4 0 Resistin DUF303 PF03629.13 ETO13877.1 - 0.0071 15.5 0.0 0.0094 15.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF303) DUF303 PF03629.13 ETO13878.1 - 1.3e-37 129.4 0.1 1.9e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF303) DUF3450 PF11932.3 ETO13879.1 - 0.005 16.1 8.3 0.19 10.9 2.4 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) DUF3602 PF12223.3 ETO13879.1 - 0.0058 16.9 0.1 0.019 15.3 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3602) DUF4279 PF14106.1 ETO13879.1 - 0.016 15.0 0.7 0.016 15.0 0.5 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4279) DUF4349 PF14257.1 ETO13879.1 - 0.052 12.7 0.3 0.21 10.7 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4349) Reo_sigmaC PF04582.7 ETO13879.1 - 0.37 9.9 7.5 3.4 6.7 1.0 2.5 2 1 2 4 4 4 0 Reovirus sigma C capsid protein CCDC155 PF14662.1 ETO13879.1 - 1.3 8.5 28.7 0.092 12.3 13.4 3.0 3 1 1 4 4 4 0 Coiled-coil region of CCDC155 NPV_P10 PF05531.7 ETO13879.1 - 3.3 8.0 12.5 1.2 9.4 0.2 4.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.5 ETO13879.1 - 4.3 7.4 25.2 0.13 12.4 7.7 3.4 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family IncA PF04156.9 ETO13879.1 - 4.5 6.8 27.2 1.9 8.0 11.2 3.3 1 1 2 3 3 3 0 IncA protein PspA_IM30 PF04012.7 ETO13879.1 - 5.6 6.2 12.6 0.36 10.1 1.3 2.8 2 1 0 3 3 3 0 PspA/IM30 family zf-CCHC PF00098.18 ETO13880.1 - 8.4 6.5 12.6 5 7.2 0.3 2.6 2 0 0 2 2 2 0 Zinc knuckle TEX19 PF15553.1 ETO13881.1 - 0.024 14.5 0.8 0.2 11.5 0.1 2.4 2 0 0 2 2 2 0 Testis-expressed protein 19 TTL PF03133.10 ETO13882.1 - 1.6e-43 148.7 3.7 5.5e-28 97.7 0.8 2.7 1 1 1 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 ETO13882.1 - 4.7e-05 22.3 0.2 0.00049 18.9 0.0 2.4 2 0 0 2 2 2 1 YheC/D like ATP-grasp Aminotran_3 PF00202.16 ETO13884.1 - 1.9e-36 125.6 0.0 2.2e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III EF-hand_1 PF00036.27 ETO13885.1 - 1e-06 27.5 0.4 2.3e-06 26.4 0.3 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 ETO13885.1 - 1.5e-05 25.0 0.1 3.8e-05 23.7 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO13885.1 - 2e-05 24.0 0.6 5.9e-05 22.6 0.4 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 ETO13885.1 - 0.00046 19.3 0.6 0.0014 17.8 0.4 1.9 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 ETO13885.1 - 0.0045 16.5 0.0 0.0092 15.5 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair Phage_connect_1 PF05135.8 ETO13885.1 - 0.0089 16.1 0.1 0.026 14.6 0.1 1.8 1 0 0 1 1 1 1 Phage gp6-like head-tail connector protein ResIII PF04851.10 ETO13885.1 - 0.12 12.1 4.3 5.7 6.7 0.7 2.4 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Bcl-2 PF00452.14 ETO13885.1 - 0.65 10.1 3.9 9 6.4 0.3 2.7 2 1 0 2 2 2 0 Apoptosis regulator proteins, Bcl-2 family SPARC_Ca_bdg PF10591.4 ETO13885.1 - 4.7 7.2 14.4 0.34 10.9 0.5 3.4 3 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region WD40 PF00400.27 ETO13887.1 - 2.8e-80 261.5 17.6 1.2e-13 50.3 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO13887.1 - 6.8e-13 48.7 4.0 4e-05 23.4 0.1 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO13887.1 - 2.3e-10 39.9 4.6 0.51 10.0 0.0 5.5 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO13887.1 - 6.8e-08 31.0 5.1 0.21 9.7 0.1 5.0 1 1 1 4 4 4 4 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 ETO13887.1 - 2e-07 30.1 3.9 0.00022 20.1 1.2 2.4 1 1 0 2 2 2 2 Coatomer WD associated region Nucleoporin_N PF08801.6 ETO13887.1 - 5.7e-06 25.3 14.6 0.032 13.0 2.9 5.4 1 1 3 4 4 4 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO13887.1 - 1.8e-05 23.2 1.4 0.071 11.3 0.2 3.2 1 1 3 4 4 4 3 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO13887.1 - 2.7e-05 23.4 1.2 1.3 8.0 0.0 4.0 1 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal DUF4221 PF13970.1 ETO13887.1 - 0.0013 18.1 0.5 3.4 6.8 0.1 3.4 1 1 0 3 3 3 1 Domain of unknown function (DUF4221) Gmad1 PF10647.4 ETO13887.1 - 0.015 14.7 0.0 2.7 7.3 0.0 3.0 2 2 0 3 3 3 0 Lipoprotein LpqB beta-propeller domain Seadorna_VP6 PF07407.6 ETO13887.1 - 0.047 12.4 0.1 0.13 11.0 0.1 1.6 2 0 0 2 2 2 0 Seadornavirus VP6 protein DHFR_2 PF06442.6 ETO13887.1 - 0.094 12.3 0.0 3.7 7.2 0.0 2.9 3 0 0 3 3 3 0 R67 dihydrofolate reductase Proteasome_A_N PF10584.4 ETO13887.1 - 0.1 11.9 5.7 19 4.7 0.0 4.8 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Resistin PF06954.6 ETO13887.1 - 0.13 12.5 4.4 9.4 6.5 0.0 4.4 1 1 5 6 6 6 0 Resistin TFIIIC_delta PF12657.2 ETO13887.1 - 0.28 10.8 3.3 2.7 7.6 0.0 3.6 1 1 3 4 4 4 0 Transcription factor IIIC subunit delta N-term Sporozoite_P67 PF05642.6 ETO13890.1 - 9.3 3.9 6.4 1.6 6.4 1.1 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Daxx PF03344.10 ETO13891.1 - 2.4 6.5 53.4 0.019 13.4 30.7 1.9 2 0 0 2 2 2 0 Daxx Family zf-RanBP PF00641.13 ETO13893.1 - 0.0081 15.2 1.1 0.015 14.3 0.7 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others SusD PF07980.6 ETO13893.1 - 0.076 12.5 0.0 0.092 12.2 0.0 1.1 1 0 0 1 1 1 0 SusD family DUF1510 PF07423.6 ETO13893.1 - 0.15 11.4 8.0 0.21 10.9 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) LETM1 PF07766.8 ETO13893.1 - 0.15 11.0 0.8 0.2 10.6 0.5 1.1 1 0 0 1 1 1 0 LETM1-like protein NusG PF02357.14 ETO13894.1 - 9.9 6.4 8.2 0.51 10.6 0.2 2.7 3 1 0 3 3 3 0 Transcription termination factor nusG TTL PF03133.10 ETO13896.1 - 1e-10 41.0 0.0 1.5e-10 40.4 0.0 1.4 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family TSA PF03249.8 ETO13896.1 - 0.16 10.4 0.9 0.17 10.3 0.6 1.1 1 0 0 1 1 1 0 Type specific antigen CDC27 PF09507.5 ETO13896.1 - 1.5 7.9 11.6 1.8 7.6 8.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 BTV_NS2 PF04514.7 ETO13896.1 - 1.6 7.5 12.1 2.1 7.1 8.4 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 OmpH PF03938.9 ETO13896.1 - 1.7 8.5 8.6 2.2 8.2 5.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Nucleo_P87 PF07267.6 ETO13896.1 - 7.6 5.0 9.7 8.8 4.8 6.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Pkinase PF00069.20 ETO13897.1 - 1.5e-44 152.1 0.5 3.3e-44 150.9 0.3 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO13897.1 - 1.7e-23 83.0 0.2 4.6e-23 81.6 0.1 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO13897.1 - 6.6e-09 35.1 0.1 1.9e-08 33.5 0.1 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETO13897.1 - 0.0034 16.4 1.0 0.0065 15.5 0.7 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO13897.1 - 0.014 15.0 0.1 0.04 13.6 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF2207 PF09972.4 ETO13897.1 - 0.13 10.8 0.5 0.19 10.2 0.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) VIT1 PF01988.14 ETO13897.1 - 0.17 11.3 0.4 0.29 10.5 0.3 1.3 1 0 0 1 1 1 0 VIT family IBR PF01485.16 ETO13898.1 - 3.8e-07 29.8 26.8 0.00035 20.3 5.3 3.4 3 0 0 3 3 3 2 IBR domain zf-C3HC4 PF00097.20 ETO13898.1 - 4.1e-06 26.3 6.9 4.1e-06 26.3 4.8 3.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO13898.1 - 0.00088 19.2 5.4 0.00088 19.2 3.7 3.9 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO13898.1 - 0.0034 17.1 13.1 0.0034 17.1 9.1 3.1 1 1 1 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 ETO13898.1 - 0.0056 16.3 15.3 0.0056 16.3 10.6 4.0 2 2 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 ETO13898.1 - 0.032 13.9 2.2 0.032 13.9 1.5 2.6 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_6 PF14835.1 ETO13898.1 - 0.047 13.4 3.9 0.052 13.3 0.5 2.6 2 0 0 2 2 2 0 zf-RING of BARD1-type protein gp32 PF08804.5 ETO13898.1 - 2.6 8.2 5.5 8.4 6.5 0.6 3.1 3 0 0 3 3 3 0 gp32 DNA binding protein like DUF2284 PF10050.4 ETO13899.1 - 0.0049 16.4 4.5 0.012 15.1 3.0 1.8 2 0 0 2 2 2 1 Predicted metal-binding protein (DUF2284) DUF4557 PF15101.1 ETO13899.1 - 0.073 12.9 10.1 0.13 12.0 7.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Gti1_Pac2 PF09729.4 ETO13899.1 - 0.15 11.9 5.6 0.048 13.5 1.6 1.7 2 0 0 2 2 2 0 Gti1/Pac2 family FCP1_C PF09309.5 ETO13899.1 - 0.17 11.1 10.0 0.28 10.4 6.9 1.2 1 0 0 1 1 1 0 FCP1, C-terminal DUF2072 PF09845.4 ETO13899.1 - 0.99 9.3 11.9 0.19 11.6 5.5 1.8 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) EIIBC-GUT_N PF03612.9 ETO13899.1 - 1 8.9 7.6 2.5 7.6 5.3 1.6 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus TEX19 PF15553.1 ETO13899.1 - 1.1 9.1 11.7 0.071 12.9 4.3 1.8 2 0 0 2 2 2 0 Testis-expressed protein 19 Nucleoside_tran PF01733.13 ETO13899.1 - 1.6 7.7 6.0 4.4 6.3 4.2 1.7 1 0 0 1 1 1 0 Nucleoside transporter Peptidase_S49_N PF08496.5 ETO13899.1 - 2.2 8.0 11.8 2.3 7.9 5.9 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Afi1 PF07792.7 ETO13899.1 - 2.8 7.9 19.3 0.21 11.6 9.1 2.0 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking RED_N PF07808.8 ETO13899.1 - 4.1 6.5 23.6 0.16 11.1 11.4 2.0 2 0 0 2 2 2 0 RED-like protein N-terminal region DUF4175 PF13779.1 ETO13899.1 - 8.4 3.9 29.2 12 3.4 20.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Gag_spuma PF03276.9 ETO13899.1 - 8.5 4.5 17.2 12 4.0 12.0 1.1 1 0 0 1 1 1 0 Spumavirus gag protein TauD PF02668.11 ETO13900.1 - 3.2e-37 128.5 0.1 4.2e-37 128.2 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family zf-B_box PF00643.19 ETO13901.1 - 6.2e-08 32.4 8.2 6.2e-08 32.4 5.7 2.5 3 0 0 3 3 3 1 B-box zinc finger Rib_recp_KP_reg PF05104.7 ETO13901.1 - 0.038 14.5 9.0 0.074 13.5 6.3 1.4 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Baculo_PEP_C PF04513.7 ETO13901.1 - 0.31 10.8 5.0 0.19 11.5 1.4 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.1 ETO13901.1 - 1.1 8.1 7.9 0.085 11.7 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) RP-C_C PF11800.3 ETO13901.1 - 9.8 5.8 9.3 4.1 7.0 0.7 2.7 2 1 0 2 2 2 0 Replication protein C C-terminal region DUF2205 PF10224.4 ETO13902.1 - 0.0019 17.7 3.3 0.017 14.6 2.7 2.2 2 0 0 2 2 2 1 Predicted coiled-coil protein (DUF2205) FTA4 PF13093.1 ETO13902.1 - 0.0023 17.4 8.9 0.0029 17.0 6.1 1.2 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Flagellar_rod PF05149.7 ETO13902.1 - 0.0047 16.1 5.5 0.0059 15.8 3.8 1.2 1 0 0 1 1 1 1 Paraflagellar rod protein FlgN PF05130.7 ETO13902.1 - 0.026 14.7 10.6 0.037 14.2 6.7 1.7 1 1 1 2 2 2 0 FlgN protein DUF106 PF01956.11 ETO13902.1 - 0.14 11.7 4.9 0.16 11.4 2.9 1.5 1 1 0 1 1 1 0 Integral membrane protein DUF106 DUF4201 PF13870.1 ETO13902.1 - 0.32 10.4 14.1 0.55 9.6 9.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) V_ATPase_I PF01496.14 ETO13902.1 - 0.69 7.7 5.7 0.74 7.5 4.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AF1Q PF15017.1 ETO13902.1 - 0.81 9.6 6.3 0.27 11.1 1.5 2.1 1 1 1 2 2 2 0 Drug resistance and apoptosis regulator ING PF12998.2 ETO13902.1 - 2.4 8.4 14.5 79 3.5 10.1 2.1 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding NTR2 PF15458.1 ETO13902.1 - 2.8 7.0 17.8 5.9 6.0 2.0 2.2 1 1 1 2 2 2 0 Nineteen complex-related protein 2 DUF342 PF03961.8 ETO13902.1 - 5.6 5.2 7.1 6.3 5.0 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Fumble PF03630.9 ETO13903.1 - 5.9e-44 150.3 0.1 7.2e-44 150.0 0.1 1.1 1 0 0 1 1 1 1 Fumble HemY_N PF07219.8 ETO13903.1 - 1.4 8.4 5.8 0.68 9.5 2.0 1.8 2 0 0 2 2 2 0 HemY protein N-terminus Ion_trans PF00520.26 ETO13904.1 - 1.6e-19 69.9 11.7 1.6e-19 69.9 8.1 2.3 2 1 0 2 2 2 1 Ion transport protein DUF202 PF02656.10 ETO13904.1 - 0.11 12.7 1.9 0.23 11.6 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Ion_trans PF00520.26 ETO13905.1 - 2.4e-14 53.0 20.5 1.2e-06 27.9 10.0 2.4 1 1 1 2 2 2 2 Ion transport protein PKD_channel PF08016.7 ETO13905.1 - 0.023 13.1 15.8 0.055 11.8 7.5 2.8 1 1 2 3 3 3 0 Polycystin cation channel SpoVIF PF14069.1 ETO13905.1 - 0.066 12.9 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 Stage VI sporulation protein F WD40 PF00400.27 ETO13906.1 - 6.6e-35 117.7 29.0 3.1e-07 30.0 0.4 6.8 6 1 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO13906.1 - 0.0044 15.2 10.0 0.0068 14.6 0.1 3.1 1 1 1 3 3 3 3 Nucleoporin Nup120/160 B_lectin PF01453.19 ETO13906.1 - 0.042 13.7 0.8 0.78 9.6 0.1 2.5 2 1 0 2 2 2 0 D-mannose binding lectin DUF4394 PF14339.1 ETO13906.1 - 0.066 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4394) U-box PF04564.10 ETO13908.1 - 1.4e-08 34.5 0.0 3.1e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-C3HC4_2 PF13923.1 ETO13908.1 - 0.00011 22.0 2.2 0.00033 20.6 1.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO13908.1 - 0.00079 19.0 1.3 0.0026 17.3 0.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 ETO13908.1 - 0.0041 16.9 2.5 0.0041 16.9 1.7 2.6 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 ETO13908.1 - 0.017 14.9 1.5 0.05 13.4 1.0 1.8 1 0 0 1 1 1 0 Ring finger domain Ras PF00071.17 ETO13909.1 - 1.5e-37 128.5 0.2 1.8e-37 128.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO13909.1 - 4.3e-09 36.8 0.1 2.7e-08 34.3 0.1 2.2 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO13909.1 - 0.00098 18.4 0.3 0.0018 17.5 0.2 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO13909.1 - 0.048 13.1 0.9 2.2 7.6 0.0 2.6 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain RNA_pol_Rpb2_1 PF04563.10 ETO13909.1 - 0.087 11.7 0.1 1.8 7.4 0.0 2.1 1 1 1 2 2 2 0 RNA polymerase beta subunit DUF843 PF05814.6 ETO13910.1 - 0.87 9.4 4.5 0.82 9.5 0.1 2.8 3 0 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) Arch_flagellin PF01917.11 ETO13910.1 - 1.3 8.5 4.4 2.5 7.6 0.6 2.4 2 1 0 2 2 2 0 Archaebacterial flagellin DUF4064 PF13273.1 ETO13910.1 - 6.1 7.0 7.4 3.6 7.7 0.6 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF4064) Mem_trans PF03547.13 ETO13911.1 - 0.022 13.0 2.6 0.022 13.0 1.8 1.1 1 0 0 1 1 1 0 Membrane transport protein PNPase PF03726.9 ETO13911.1 - 0.04 14.1 0.2 0.14 12.4 0.1 1.9 1 0 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Menin PF05053.8 ETO13911.1 - 3 5.8 12.6 4 5.4 8.7 1.2 1 0 0 1 1 1 0 Menin DUF2457 PF10446.4 ETO13912.1 - 0.0051 15.5 25.3 0.0073 15.0 17.6 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2457) PI3K_1B_p101 PF10486.4 ETO13912.1 - 0.22 9.0 3.5 0.25 8.8 2.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Daxx PF03344.10 ETO13912.1 - 0.29 9.5 21.4 0.33 9.3 14.8 1.1 1 0 0 1 1 1 0 Daxx Family RRN3 PF05327.6 ETO13912.1 - 7.9 4.4 7.4 9.6 4.1 5.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Upf2 PF04050.9 ETO13912.1 - 9.8 5.9 14.0 18 5.0 9.7 1.5 1 0 0 1 1 1 0 Up-frameshift suppressor 2 TPR_12 PF13424.1 ETO13913.1 - 1.5e-128 418.9 24.5 3.6e-25 87.7 0.2 6.3 3 2 5 8 8 8 8 Tetratricopeptide repeat TPR_11 PF13414.1 ETO13913.1 - 4.7e-58 192.7 22.7 4.8e-15 54.9 0.4 6.3 6 0 0 6 6 6 5 TPR repeat TPR_10 PF13374.1 ETO13913.1 - 7.6e-55 181.4 0.0 9.8e-08 31.6 0.0 10.1 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_1 PF00515.23 ETO13913.1 - 2.1e-52 172.6 49.0 1.3e-09 37.1 0.4 9.9 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.12 ETO13913.1 - 1.7e-48 158.6 37.8 3.1e-07 29.7 0.2 9.6 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_7 PF13176.1 ETO13913.1 - 5.1e-46 150.8 9.3 9.5e-09 34.4 0.0 8.5 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.1 ETO13913.1 - 2e-41 136.6 58.9 1.4e-08 33.9 1.3 9.7 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_17 PF13431.1 ETO13913.1 - 1.3e-20 71.7 11.0 0.0053 16.8 0.0 9.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO13913.1 - 1.4e-19 70.1 0.0 0.00029 21.4 0.0 5.4 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_6 PF13174.1 ETO13913.1 - 2.6e-14 52.6 7.5 0.17 12.3 0.0 8.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO13913.1 - 7.5e-13 47.8 0.0 0.54 11.0 0.0 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO13913.1 - 5.6e-10 39.2 25.8 5.3e-05 23.2 1.7 5.3 1 1 4 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO13913.1 - 1.5e-09 38.0 0.5 0.052 13.8 0.1 4.6 4 1 1 5 5 4 3 Tetratricopeptide repeat MIT PF04212.13 ETO13913.1 - 1.5e-08 34.3 20.2 0.014 15.2 0.1 7.0 8 0 0 8 8 7 3 MIT (microtubule interacting and transport) domain Peptidase_C14 PF00656.17 ETO13913.1 - 1.7e-07 31.1 0.1 5.4e-07 29.5 0.1 1.8 1 0 0 1 1 1 1 Caspase domain SHNi-TPR PF10516.4 ETO13913.1 - 2.4e-05 23.4 4.3 16 4.8 0.0 6.8 7 0 0 7 7 7 0 SHNi-TPR Mob_Pre PF01076.14 ETO13913.1 - 3.4e-05 23.5 5.3 0.0025 17.4 0.1 4.8 3 2 2 5 5 5 2 Plasmid recombination enzyme PPR PF01535.15 ETO13913.1 - 0.00096 18.9 23.5 0.1 12.5 0.1 7.7 8 0 0 8 8 7 2 PPR repeat TPR_3 PF07720.7 ETO13913.1 - 0.0034 17.1 25.6 0.92 9.3 0.3 7.5 8 0 0 8 8 7 1 Tetratricopeptide repeat Sel1 PF08238.7 ETO13913.1 - 0.0049 17.4 11.7 2.3 8.9 0.1 5.9 7 0 0 7 7 6 1 Sel1 repeat RPN7 PF10602.4 ETO13913.1 - 0.022 14.1 24.5 3.2 7.0 0.2 7.1 3 1 4 7 7 7 0 26S proteasome subunit RPN7 TPR_5 PF12688.2 ETO13913.1 - 0.15 12.1 0.0 8.1 6.5 0.0 3.3 3 2 2 5 5 4 0 Tetratrico peptide repeat DUF357 PF04010.8 ETO13913.1 - 0.31 10.7 10.5 0.69 9.6 0.1 4.9 3 2 3 6 6 6 0 Protein of unknown function (DUF357) Fis1_TPR_C PF14853.1 ETO13913.1 - 3.8 7.4 15.8 38 4.2 0.2 5.9 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Polyoma_coat2 PF00761.15 ETO13914.1 - 0.094 12.2 0.1 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Polyomavirus coat protein Glyco_transf_10 PF00852.14 ETO13915.1 - 0.00013 20.6 0.1 0.00028 19.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) IL28A PF15177.1 ETO13916.1 - 0.0071 15.8 0.1 0.0071 15.8 0.0 1.1 1 0 0 1 1 1 1 Interleukin-28A 7TM_GPCR_Srw PF10324.4 ETO13916.1 - 0.041 13.0 0.0 0.044 12.9 0.0 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw DUF3091 PF11291.3 ETO13916.1 - 0.042 13.7 1.7 0.05 13.5 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3091) Exo_endo_phos PF03372.18 ETO13917.1 - 1.8e-06 28.0 0.1 3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SAGA-Tad1 PF12767.2 ETO13917.1 - 0.0066 16.1 4.8 0.0066 16.1 3.3 2.1 2 0 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit HSP90 PF00183.13 ETO13917.1 - 0.065 11.6 10.8 0.087 11.2 7.5 1.1 1 0 0 1 1 1 0 Hsp90 protein Mcp5_PH PF12814.2 ETO13918.1 - 1.1e-06 28.5 0.1 1.1e-06 28.5 0.1 2.4 3 0 0 3 3 3 1 Meiotic cell cortex C-terminal pleckstrin homology Pox_P4B PF03292.9 ETO13918.1 - 0.071 11.0 3.3 0.11 10.4 2.3 1.2 1 0 0 1 1 1 0 Poxvirus P4B major core protein Mem_trans PF03547.13 ETO13918.1 - 0.24 9.6 1.4 0.24 9.6 0.9 1.2 1 0 0 1 1 1 0 Membrane transport protein Herpes_DNAp_acc PF04929.7 ETO13918.1 - 4.4 6.1 17.6 7.3 5.4 12.2 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Neur_chan_memb PF02932.11 ETO13918.1 - 8.2 6.2 8.0 12 5.6 5.6 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TPD PF14811.1 ETO13919.1 - 4.7e-13 48.8 0.0 7.5e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif MSC PF09402.5 ETO13919.1 - 0.013 14.2 0.1 0.66 8.6 0.0 2.1 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain Amino_oxidase PF01593.19 ETO13920.1 - 5.4e-44 151.0 0.0 3.1e-33 115.5 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 ETO13920.1 - 5.4e-12 45.5 0.0 1.5e-11 44.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETO13920.1 - 2.3e-08 33.3 0.0 3.4e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETO13920.1 - 7.7e-08 31.6 0.3 1.3e-07 30.8 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 ETO13920.1 - 3.5e-06 26.3 0.0 7.2e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 ETO13920.1 - 4e-05 22.8 0.1 0.00021 20.4 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 ETO13920.1 - 0.00017 21.5 0.0 0.00017 21.5 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETO13920.1 - 0.00017 21.9 0.0 0.00044 20.6 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETO13920.1 - 0.00093 17.7 0.1 0.00093 17.7 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 ETO13920.1 - 0.0011 17.8 0.0 0.003 16.4 0.0 1.7 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 ETO13920.1 - 0.0017 17.4 0.2 0.0033 16.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 ETO13920.1 - 0.0018 17.2 0.0 0.0029 16.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 ETO13920.1 - 0.029 14.4 0.0 0.074 13.1 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETO13920.1 - 0.099 12.4 0.1 0.3 10.8 0.0 1.9 2 0 0 2 2 1 0 FAD-NAD(P)-binding Myc_N PF01056.13 ETO13921.1 - 0.15 11.2 6.2 0.2 10.7 4.3 1.2 1 0 0 1 1 1 0 Myc amino-terminal region CDC45 PF02724.9 ETO13921.1 - 0.21 9.5 10.1 0.28 9.1 7.0 1.1 1 0 0 1 1 1 0 CDC45-like protein BTV_NS2 PF04514.7 ETO13921.1 - 0.32 9.8 7.6 0.37 9.6 5.2 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 YqfQ PF14181.1 ETO13921.1 - 0.49 10.4 7.1 0.86 9.6 4.9 1.4 1 0 0 1 1 1 0 YqfQ-like protein TRAP_alpha PF03896.11 ETO13921.1 - 0.5 9.3 8.0 0.75 8.7 5.6 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Daxx PF03344.10 ETO13921.1 - 0.9 7.9 13.4 1.2 7.5 9.3 1.1 1 0 0 1 1 1 0 Daxx Family Hydantoinase_A PF01968.13 ETO13922.1 - 3.8e-58 196.8 0.0 4.8e-58 196.5 0.0 1.0 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase TrkA_C PF02080.16 ETO13923.1 - 1.1e-08 34.4 0.0 7.8e-08 31.8 0.0 2.4 2 1 1 3 3 3 1 TrkA-C domain Pex2_Pex12 PF04757.9 ETO13925.1 - 2.7e-26 92.4 3.0 2.7e-26 92.4 2.1 1.7 2 0 0 2 2 2 1 Pex2 / Pex12 amino terminal region TAFII28 PF04719.9 ETO13926.1 - 2.5e-11 43.1 0.9 7e-10 38.5 0.4 2.8 2 0 0 2 2 2 1 hTAFII28-like protein conserved region Nexin_C PF08628.7 ETO13926.1 - 0.015 15.4 0.2 0.13 12.3 0.0 2.8 3 0 0 3 3 3 0 Sorting nexin C terminal Papo_T_antigen PF02380.10 ETO13926.1 - 0.071 13.0 2.8 0.19 11.6 1.9 1.7 1 0 0 1 1 1 0 T-antigen specific domain INCENP_ARK-bind PF03941.10 ETO13926.1 - 0.13 12.1 0.0 0.13 12.1 0.0 4.3 4 0 0 4 4 4 0 Inner centromere protein, ARK binding region Baculo_LEF-11 PF06385.7 ETO13929.1 - 0.025 14.6 1.6 0.044 13.8 0.8 1.7 1 1 1 2 2 2 0 Baculovirus LEF-11 protein Peptidase_C65 PF10275.4 ETO13929.1 - 0.1 11.9 1.9 0.12 11.6 1.3 1.1 1 0 0 1 1 1 0 Peptidase C65 Otubain DUF4519 PF15012.1 ETO13929.1 - 9.4 6.2 6.8 6.2 6.8 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Chalcone PF02431.10 ETO13930.1 - 0.0093 15.3 0.2 0.015 14.7 0.2 1.3 1 0 0 1 1 1 1 Chalcone-flavanone isomerase YxiJ PF14176.1 ETO13930.1 - 0.017 15.2 1.7 0.024 14.7 0.6 1.7 1 1 0 1 1 1 0 YxiJ-like protein DUF3670 PF12419.3 ETO13930.1 - 0.022 14.1 0.4 0.052 12.9 0.2 1.5 1 1 0 1 1 1 0 SNF2 Helicase protein E2R135 PF11570.3 ETO13930.1 - 0.12 12.4 2.9 0.2 11.7 2.0 1.3 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 FKBP_N PF01346.13 ETO13930.1 - 1.4 8.9 5.4 4.3 7.4 0.9 2.2 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Sporozoite_P67 PF05642.6 ETO13931.1 - 0.16 9.7 4.0 0.24 9.2 2.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.7 ETO13931.1 - 0.6 7.9 8.9 0.76 7.6 6.2 1.1 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 ETO13931.1 - 0.7 9.4 9.8 1.2 8.6 6.8 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 ETO13931.1 - 2.5 6.0 9.5 3.5 5.5 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 ETO13931.1 - 4 6.0 21.4 7.6 5.1 14.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RXT2_N PF08595.6 ETO13931.1 - 4.7 7.0 8.3 13 5.5 5.8 1.9 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop25 PF09805.4 ETO13931.1 - 7.7 6.5 12.4 14 5.7 8.6 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) HSP90 PF00183.13 ETO13931.1 - 8.6 4.6 9.2 12 4.1 6.4 1.1 1 0 0 1 1 1 0 Hsp90 protein 5_nucleotid PF05761.9 ETO13932.1 - 2.2e-58 197.9 0.4 2.6e-58 197.6 0.3 1.0 1 0 0 1 1 1 1 5' nucleotidase family HAD_2 PF13419.1 ETO13932.1 - 0.011 16.0 0.1 0.29 11.3 0.0 2.7 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase DUF4546 PF15079.1 ETO13932.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4546) DUF3328 PF11807.3 ETO13934.1 - 0.02 14.6 0.1 0.02 14.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) DUF4365 PF14280.1 ETO13934.1 - 0.63 9.7 6.0 0.15 11.7 1.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4365) Dymeclin PF09742.4 ETO13935.1 - 8.1e-16 57.2 25.8 1.5e-14 53.1 17.9 2.8 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein SR-25 PF10500.4 ETO13935.1 - 0.01 15.3 2.1 0.01 15.3 1.5 3.5 3 1 1 4 4 4 0 Nuclear RNA-splicing-associated protein Cnd1_N PF12922.2 ETO13935.1 - 0.066 12.8 4.1 0.21 11.1 0.3 2.9 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1, N-term SOBP PF15279.1 ETO13935.1 - 0.14 12.5 9.0 1.6 9.0 1.0 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein DUF2140 PF09911.4 ETO13936.1 - 0.038 13.1 0.0 0.11 11.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) MRAP PF15183.1 ETO13936.1 - 0.13 11.8 3.5 0.2 11.2 1.3 2.2 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family DUF3753 PF12575.3 ETO13936.1 - 3.9 7.3 7.9 0.58 9.9 1.9 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3753) Ras PF00071.17 ETO13937.1 - 6.1e-13 48.4 0.0 7.6e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Hyccin PF09790.4 ETO13937.1 - 0.033 13.0 0.1 0.041 12.7 0.1 1.1 1 0 0 1 1 1 0 Hyccin Miro PF08477.8 ETO13938.1 - 8.4e-10 39.1 0.2 1.1e-09 38.7 0.1 1.1 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 ETO13938.1 - 3.1e-08 33.1 0.7 4.8e-08 32.5 0.5 1.3 1 0 0 1 1 1 1 Ras family NB-ARC PF00931.17 ETO13938.1 - 0.00057 18.8 0.1 0.0006 18.7 0.1 1.1 1 0 0 1 1 1 1 NB-ARC domain MMR_HSR1 PF01926.18 ETO13938.1 - 0.00058 19.7 0.3 0.00091 19.1 0.2 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 ETO13938.1 - 0.0021 17.2 0.0 0.0024 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 ETO13938.1 - 0.0041 17.2 0.0 0.0055 16.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 ETO13938.1 - 0.0093 15.6 0.5 0.013 15.2 0.2 1.4 1 1 0 1 1 1 1 Archaeal ATPase cobW PF02492.14 ETO13938.1 - 0.012 15.1 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 ETO13938.1 - 0.017 14.1 0.1 0.019 13.9 0.1 1.1 1 0 0 1 1 1 0 Septin Arf PF00025.16 ETO13938.1 - 0.026 13.7 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family MobB PF03205.9 ETO13938.1 - 0.062 13.0 0.3 0.13 11.9 0.1 1.6 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 ETO13938.1 - 0.087 12.3 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 ETO13938.1 - 0.098 12.5 0.0 0.2 11.5 0.0 1.5 2 0 0 2 2 2 0 AAA domain PhosphMutase PF10143.4 ETO13939.1 - 0.25 10.9 4.3 0.058 13.0 0.5 1.7 2 0 0 2 2 2 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Peptidase_C6 PF00851.13 ETO13939.1 - 1.6 7.2 13.0 4.3 5.8 4.4 2.0 1 1 1 2 2 2 0 Helper component proteinase DUF1757 PF08560.5 ETO13941.1 - 1.2e-14 54.2 0.0 1.6e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1757) Sec62 PF03839.11 ETO13941.1 - 0.17 11.2 0.4 0.26 10.6 0.3 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF739 PF05339.6 ETO13942.1 - 0.079 12.7 0.5 0.15 11.8 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF739) CDC45 PF02724.9 ETO13943.1 - 0.011 13.8 6.8 0.016 13.2 4.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 ETO13943.1 - 0.013 14.0 10.5 0.02 13.4 7.3 1.2 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 ETO13943.1 - 0.076 10.9 14.2 0.67 7.8 8.6 2.1 2 0 0 2 2 2 0 Nop14-like family DUF2457 PF10446.4 ETO13943.1 - 0.27 9.9 15.9 0.43 9.2 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CobT PF06213.7 ETO13943.1 - 5 6.1 15.5 8.2 5.4 10.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Astacin PF01400.19 ETO13944.1 - 0.0074 15.6 0.1 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) PI3Ka PF00613.15 ETO13948.1 - 4.1e-42 143.4 3.2 4.1e-42 143.4 2.3 1.6 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 ETO13948.1 - 5.2e-22 78.4 0.2 1.9e-21 76.6 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 ETO13948.1 - 0.0081 15.9 0.1 3.2 7.5 0.0 3.1 3 0 0 3 3 3 2 Phosphoinositide 3-kinase C2 PI3_PI4_kinase PF00454.22 ETO13949.1 - 0.0076 15.7 1.3 0.088 12.2 0.9 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pkinase PF00069.20 ETO13950.1 - 1.5e-20 73.4 0.0 2.7e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO13950.1 - 1.4e-14 53.7 0.1 3.5e-14 52.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase ICE2 PF08426.5 ETO13950.1 - 0.015 13.9 0.1 0.019 13.5 0.0 1.1 1 0 0 1 1 1 0 ICE2 Shisa PF13908.1 ETO13950.1 - 0.057 13.6 0.0 0.096 12.8 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Mem_trans PF03547.13 ETO13950.1 - 0.11 10.7 0.0 0.14 10.3 0.0 1.1 1 0 0 1 1 1 0 Membrane transport protein Myc_N PF01056.13 ETO13952.1 - 0.13 11.3 2.2 0.13 11.4 1.5 1.1 1 0 0 1 1 1 0 Myc amino-terminal region TRAP_alpha PF03896.11 ETO13952.1 - 2.1 7.2 6.2 2.4 7.0 4.3 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nucleoplasmin PF03066.10 ETO13952.1 - 6.2 6.3 13.0 8.8 5.8 9.0 1.4 1 1 0 1 1 1 0 Nucleoplasmin CbiA PF01656.18 ETO13954.1 - 0.0018 17.6 0.0 0.0041 16.5 0.0 1.7 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain Filament PF00038.16 ETO13955.1 - 0.0018 17.8 18.7 0.0018 17.8 13.0 5.6 1 1 3 4 4 4 1 Intermediate filament protein Reo_sigmaC PF04582.7 ETO13955.1 - 0.034 13.3 39.0 0.034 13.3 0.8 5.7 2 2 6 8 8 8 0 Reovirus sigma C capsid protein Pep3_Vps18 PF05131.9 ETO13956.1 - 8e-23 80.5 0.1 8e-23 80.5 0.0 1.8 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family FHA PF00498.21 ETO13957.1 - 2.1e-13 50.1 0.2 2e-12 47.0 0.1 2.3 1 1 0 1 1 1 1 FHA domain zf-C3HC4_4 PF15227.1 ETO13957.1 - 0.0026 17.5 9.4 0.0085 15.9 6.6 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 ETO13957.1 - 0.0034 16.9 9.7 0.016 14.8 6.7 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO13957.1 - 0.0038 16.8 12.5 0.0073 15.9 8.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Peroxin-13_N PF04088.8 ETO13957.1 - 0.018 15.0 0.6 0.018 15.0 0.4 3.5 3 1 1 4 4 4 0 Peroxin 13, N-terminal region zf-C3HC4_2 PF13923.1 ETO13957.1 - 0.03 14.3 10.8 0.078 13.0 7.5 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FAM72 PF14976.1 ETO13957.1 - 0.16 11.7 6.8 7.3 6.4 4.7 2.7 1 1 0 1 1 1 0 FAM72 protein zf-RING_UBOX PF13445.1 ETO13957.1 - 1.7 8.4 11.7 1.2 8.8 6.1 2.3 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.1 ETO13957.1 - 2.8 7.8 13.6 5.6 6.8 9.4 1.5 1 0 0 1 1 1 0 Ring finger domain YjgP_YjgQ PF03739.9 ETO13957.1 - 5.1 5.7 7.0 11 4.7 4.8 1.6 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Pkinase PF00069.20 ETO13958.1 - 7.3e-35 120.3 0.9 1.8e-34 119.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO13958.1 - 7.7e-16 57.9 0.0 1.4e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Dynamitin PF04912.9 ETO13959.1 - 3.7e-20 72.0 19.9 4.5e-20 71.8 13.8 1.1 1 0 0 1 1 1 1 Dynamitin Pox_A_type_inc PF04508.7 ETO13959.1 - 0.015 14.9 3.1 0.065 13.0 2.1 2.1 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DASH_Dad3 PF08656.5 ETO13959.1 - 0.28 10.8 4.8 0.41 10.3 0.3 3.1 2 2 1 3 3 3 0 DASH complex subunit Dad3 DUF4110 PF13422.1 ETO13959.1 - 1 9.2 6.1 0.29 10.9 0.4 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4110) Menin PF05053.8 ETO13959.1 - 2.9 5.9 11.4 5 5.1 7.9 1.4 1 0 0 1 1 1 0 Menin LMBR1 PF04791.11 ETO13959.1 - 4.5 5.7 6.1 3.8 5.9 3.6 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein Occludin_ELL PF07303.8 ETO13959.1 - 6.5 7.5 13.2 14 6.4 3.1 3.5 2 2 1 4 4 4 0 Occludin homology domain HTH_40 PF14493.1 ETO13960.1 - 0.00018 21.6 0.2 0.00074 19.6 0.0 2.2 2 1 1 3 3 3 1 Helix-turn-helix domain Phage_Nu1 PF07471.7 ETO13961.1 - 0.0026 17.2 2.4 0.0056 16.1 1.6 1.5 1 0 0 1 1 1 1 Phage DNA packaging protein Nu1 Secretin_N_2 PF07655.8 ETO13962.1 - 1.5 9.2 11.8 0.23 11.8 2.3 2.6 2 0 0 2 2 2 0 Secretin N-terminal domain Secretin_N_2 PF07655.8 ETO13963.1 - 0.79 10.1 10.8 0.15 12.4 5.0 1.7 2 0 0 2 2 2 0 Secretin N-terminal domain MACPF PF01823.14 ETO13963.1 - 3 7.4 12.4 1.6 8.3 7.3 1.5 1 1 0 1 1 1 0 MAC/Perforin domain DUF3827 PF12877.2 ETO13966.1 - 0.021 12.9 3.4 0.031 12.3 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Choline_transpo PF04515.7 ETO13968.1 - 2.4e-33 115.2 23.2 2.2e-17 62.8 4.4 2.1 2 0 0 2 2 2 2 Plasma-membrane choline transporter UPF0154 PF03672.8 ETO13968.1 - 1.6 8.3 4.0 0.44 10.2 0.5 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) TM_helix PF05552.7 ETO13968.1 - 2.3 7.9 5.0 1.3 8.7 0.2 2.5 2 0 0 2 2 2 0 Conserved TM helix TMEM169 PF15052.1 ETO13969.1 - 0.075 12.9 0.6 0.075 12.9 0.4 1.7 2 0 0 2 2 2 0 TMEM169 protein family JmjC PF02373.17 ETO13971.1 - 1.2e-08 35.1 0.1 7.5e-07 29.3 0.0 2.7 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 ETO13971.1 - 4.8e-08 32.8 4.5 2e-07 30.7 0.5 2.4 2 1 1 3 3 3 2 Cupin-like domain Cupin_4 PF08007.7 ETO13971.1 - 0.00053 19.3 0.0 0.00088 18.5 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein C2 PF00168.25 ETO13972.1 - 2.4e-08 33.7 0.5 5.9e-08 32.4 0.4 1.7 1 0 0 1 1 1 1 C2 domain Myosin_tail_1 PF01576.14 ETO13972.1 - 0.00064 17.5 26.6 0.00082 17.2 18.5 1.1 1 0 0 1 1 1 1 Myosin tail Reo_sigmaC PF04582.7 ETO13972.1 - 0.0014 17.8 6.3 0.0014 17.8 4.4 1.4 1 1 0 1 1 1 1 Reovirus sigma C capsid protein DivIC PF04977.10 ETO13972.1 - 0.0037 16.7 3.8 0.0037 16.7 2.6 4.1 1 1 3 4 4 4 2 Septum formation initiator WD40_alt PF14077.1 ETO13972.1 - 0.053 13.1 1.8 0.67 9.6 0.1 2.5 2 0 0 2 2 2 0 Alternative WD40 repeat motif DUF2205 PF10224.4 ETO13972.1 - 0.1 12.1 21.9 0.026 14.0 4.4 3.2 1 1 2 3 3 3 0 Predicted coiled-coil protein (DUF2205) GAS PF13851.1 ETO13972.1 - 0.15 11.2 30.4 0.4 9.8 4.2 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 ETO13972.1 - 0.15 10.6 30.3 1.2 7.7 20.9 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 ETO13972.1 - 0.2 11.2 39.5 0.43 10.1 17.3 2.1 1 1 1 2 2 2 0 IncA protein IFT57 PF10498.4 ETO13972.1 - 0.34 9.5 29.8 0.98 8.0 5.1 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 CALCOCO1 PF07888.6 ETO13972.1 - 0.49 8.6 22.7 0.63 8.2 15.7 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Mod_r PF07200.8 ETO13972.1 - 0.54 10.1 31.5 0.91 9.4 5.4 2.4 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Cmyb_C PF09316.5 ETO13972.1 - 0.6 9.7 14.2 0.024 14.3 4.7 2.1 1 1 1 2 2 2 0 C-myb, C-terminal Sec8_exocyst PF04048.9 ETO13972.1 - 0.93 9.1 18.3 0.19 11.3 9.7 1.9 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain CCDC155 PF14662.1 ETO13972.1 - 0.97 8.9 32.6 2.3 7.7 22.6 1.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 ERM PF00769.14 ETO13972.1 - 1.3 8.5 33.1 4.4 6.7 22.9 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF3584 PF12128.3 ETO13972.1 - 2.1 5.5 28.2 3 5.0 19.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) BLOC1_2 PF10046.4 ETO13972.1 - 3.4 7.8 21.5 2.4 8.3 6.9 2.6 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 V_ATPase_I PF01496.14 ETO13972.1 - 3.8 5.2 27.7 5.6 4.6 4.4 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 ETO13972.1 - 4.6 6.1 35.9 2.5 7.0 6.0 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 ETO13972.1 - 8 6.3 35.8 1.5 8.7 15.9 2.2 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.16 ETO13972.1 - 8.2 6.4 23.2 1.8 8.5 1.1 3.7 2 2 1 3 3 3 0 bZIP transcription factor AATF-Che1 PF13339.1 ETO13972.1 - 8.5 6.5 26.3 0.63 10.1 9.6 3.0 1 1 2 3 3 3 0 Apoptosis antagonizing transcription factor CAF-1_p150 PF11600.3 ETO13973.1 - 4.5 6.5 1.4 10 5.4 1.0 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FPL PF09758.4 ETO13974.1 - 0.0062 16.3 0.1 0.018 14.8 0.1 1.8 1 0 0 1 1 1 1 Uncharacterised conserved protein ATG2_CAD PF13329.1 ETO13975.1 - 0.00038 20.0 0.1 0.4 10.2 0.0 2.6 2 0 0 2 2 2 2 Autophagy-related protein 2 CAD motif Pepsin-I3 PF06394.8 ETO13976.1 - 0.0048 16.5 1.3 0.0048 16.5 0.9 2.2 2 0 0 2 2 2 1 Pepsin inhibitor-3-like repeated domain fn3 PF00041.16 ETO13976.1 - 0.0049 16.9 2.7 0.35 11.0 0.5 3.1 2 1 0 2 2 2 1 Fibronectin type III domain CobU PF02283.11 ETO13976.1 - 0.038 13.4 4.0 0.072 12.5 2.8 1.4 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase DUF1515 PF07439.6 ETO13976.1 - 0.51 10.1 3.9 1.4 8.7 2.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Allexi_40kDa PF05549.6 ETO13976.1 - 5.8 6.1 6.9 2.1 7.5 2.4 1.9 1 1 1 2 2 2 0 Allexivirus 40kDa protein TFIIA PF03153.8 ETO13977.1 - 0.0077 16.1 7.2 0.01 15.7 5.0 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit NB PF04159.8 ETO13978.1 - 0.013 15.2 0.3 0.055 13.2 0.0 2.2 2 0 0 2 2 2 0 NB glycoprotein TPR_11 PF13414.1 ETO13979.1 - 1.9e-28 97.8 31.5 7.2e-06 25.5 0.1 7.9 6 2 2 8 8 8 8 TPR repeat TPR_16 PF13432.1 ETO13979.1 - 1.9e-15 57.0 4.4 0.00044 20.8 0.0 5.7 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO13979.1 - 2.7e-14 51.8 22.8 0.059 13.3 0.0 9.4 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_12 PF13424.1 ETO13979.1 - 2e-13 50.0 33.2 0.007 16.2 1.9 6.9 6 3 2 8 8 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 ETO13979.1 - 2.2e-13 49.5 0.5 0.18 12.5 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO13979.1 - 1.3e-11 43.4 22.3 0.0004 19.9 0.3 9.1 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO13979.1 - 3.1e-11 42.3 33.0 0.0016 17.9 0.5 9.4 9 1 0 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO13979.1 - 7.8e-09 35.0 22.5 0.18 12.0 0.0 8.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO13979.1 - 3e-08 33.8 11.3 0.21 11.9 0.0 6.7 8 1 0 8 8 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO13979.1 - 0.0004 19.9 9.7 0.8 9.6 0.0 6.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO13979.1 - 0.0033 17.7 12.5 14 6.4 0.2 5.7 6 0 0 6 6 4 0 Tetratricopeptide repeat Apc3 PF12895.2 ETO13979.1 - 0.12 12.5 0.2 0.12 12.5 0.1 5.7 4 1 2 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 Zip PF02535.17 ETO13979.1 - 0.47 9.4 7.2 0.019 13.9 0.4 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter TPR_11 PF13414.1 ETO13980.1 - 3.6e-08 32.9 7.4 0.00061 19.3 2.5 2.5 1 1 1 2 2 2 2 TPR repeat TPR_17 PF13431.1 ETO13980.1 - 3.7e-08 32.9 2.1 0.29 11.4 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO13980.1 - 0.0018 18.5 3.1 0.032 14.5 0.2 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO13980.1 - 0.0065 16.0 9.8 3.4 7.4 0.7 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO13980.1 - 0.0096 15.7 8.6 0.074 12.9 0.6 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO13980.1 - 0.021 15.4 0.4 0.88 10.3 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETO13980.1 - 0.041 14.5 4.2 0.16 12.7 2.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETO13980.1 - 0.2 11.6 2.6 9.3 6.2 0.1 2.6 1 1 0 2 2 2 0 Tetratricopeptide repeat Pup PF05639.6 ETO13981.1 - 0.44 11.0 9.9 1.9 9.0 3.6 2.4 2 0 0 2 2 2 0 Pup-like protein IFT20 PF14931.1 ETO13981.1 - 0.47 10.3 11.2 0.37 10.6 0.3 2.4 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 DUF2368 PF10166.4 ETO13981.1 - 0.49 10.0 0.0 0.49 10.0 0.0 2.5 2 1 1 3 3 3 0 Uncharacterised conserved protein (DUF2368) PCNP PF15473.1 ETO13981.1 - 0.55 10.5 5.2 1.1 9.5 3.6 1.5 1 0 0 1 1 1 0 PEST, proteolytic signal-containing nuclear protein family RhoGEF PF00621.15 ETO13982.1 - 3.2e-08 33.6 3.9 1.6e-07 31.4 2.7 1.8 1 1 0 1 1 1 1 RhoGEF domain DUF815 PF05673.8 ETO13982.1 - 0.019 13.9 0.1 0.023 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PHD_2 PF13831.1 ETO13982.1 - 0.062 12.6 0.5 0.12 11.7 0.4 1.4 1 0 0 1 1 1 0 PHD-finger YajC PF02699.10 ETO13982.1 - 0.66 9.6 2.9 1.9 8.1 2.0 1.8 1 0 0 1 1 1 0 Preprotein translocase subunit YMF19 PF02326.10 ETO13982.1 - 1.5 9.4 9.3 0.16 12.5 2.5 2.2 2 1 0 2 2 2 0 Plant ATP synthase F0 IncA PF04156.9 ETO13983.1 - 1 8.9 2.6 1.2 8.6 0.3 2.0 2 0 0 2 2 2 0 IncA protein Secretin_N_2 PF07655.8 ETO13983.1 - 7.3 7.0 29.6 17 5.8 20.5 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain Pex16 PF08610.5 ETO13983.1 - 9.9 5.0 12.9 0.97 8.3 5.7 1.6 1 1 1 2 2 2 0 Peroxisomal membrane protein (Pex16) Met_10 PF02475.11 ETO13984.1 - 3.6e-53 180.1 0.1 5.5e-53 179.5 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein CoxIIa PF08113.6 ETO13985.1 - 0.067 12.9 0.6 0.067 12.9 0.4 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IIa family zf-TRAF PF02176.13 ETO13986.1 - 0.0025 18.1 3.5 0.0047 17.2 1.5 1.9 1 1 1 2 2 2 1 TRAF-type zinc finger IncA PF04156.9 ETO13987.1 - 0.012 15.1 9.8 0.019 14.5 6.8 1.2 1 0 0 1 1 1 0 IncA protein Spc7 PF08317.6 ETO13987.1 - 1 7.9 15.8 1.5 7.3 11.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein MitMem_reg PF13012.1 ETO13987.1 - 1.7 8.7 13.0 0.93 9.6 0.9 2.2 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function MAD PF05557.8 ETO13987.1 - 3.1 5.7 22.5 17 3.3 14.6 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein Atg14 PF10186.4 ETO13987.1 - 4.7 6.0 12.0 7.3 5.4 8.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 U-box PF04564.10 ETO13988.1 - 1.3e-23 82.6 1.4 2.7e-23 81.7 0.3 2.1 2 0 0 2 2 2 1 U-box domain Ufd2P_core PF10408.4 ETO13988.1 - 4.5e-10 38.4 21.2 4.5e-10 38.4 14.7 1.9 2 1 0 2 2 2 1 Ubiquitin elongating factor core RNA_pol_Rpc4 PF05132.9 ETO13988.1 - 0.03 14.2 0.1 0.072 13.0 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 ZZ PF00569.12 ETO13989.1 - 0.00011 21.5 4.8 0.00013 21.3 0.6 2.4 2 0 0 2 2 2 1 Zinc finger, ZZ type zf-Di19 PF05605.7 ETO13990.1 - 1.1e-05 25.4 2.1 2.9e-05 24.0 1.5 1.7 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding ZZ PF00569.12 ETO13990.1 - 0.66 9.5 13.8 0.32 10.5 7.5 2.0 2 0 0 2 2 2 0 Zinc finger, ZZ type Peptidase_C14 PF00656.17 ETO13991.1 - 5.3e-05 23.0 0.2 0.00058 19.6 0.1 2.3 1 1 0 1 1 1 1 Caspase domain Toxin_21 PF08091.6 ETO13991.1 - 0.014 15.1 1.6 0.014 15.1 1.1 1.7 2 0 0 2 2 2 0 Spider insecticidal peptide XPG_I PF00867.13 ETO13991.1 - 0.63 10.1 2.6 0.82 9.7 0.0 2.6 3 2 0 3 3 3 0 XPG I-region Motile_Sperm PF00635.21 ETO13992.1 - 3.5e-06 26.6 9.1 0.035 13.7 0.1 3.7 3 1 1 4 4 4 3 MSP (Major sperm protein) domain PapD_N PF00345.15 ETO13992.1 - 0.065 13.0 0.4 0.62 9.8 0.1 2.3 2 0 0 2 2 2 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Myotoxins PF00819.12 ETO13992.1 - 0.39 10.8 0.1 0.39 10.8 0.1 2.7 4 0 0 4 4 4 0 Myotoxin LepA_C PF06421.7 ETO13993.1 - 0.054 13.3 3.3 0.074 12.9 2.3 1.2 1 0 0 1 1 1 0 GTP-binding protein LepA C-terminus DUF4385 PF14328.1 ETO13993.1 - 0.37 10.6 4.5 1.2 9.0 0.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4385) VID27 PF08553.5 ETO13994.1 - 0.0057 14.9 0.7 0.0058 14.9 0.5 1.1 1 0 0 1 1 1 1 VID27 cytoplasmic protein CDC45 PF02724.9 ETO13994.1 - 0.022 12.8 0.2 0.023 12.7 0.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.6 ETO13994.1 - 0.025 14.3 2.5 0.038 13.7 1.7 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Radial_spoke PF04712.7 ETO13994.1 - 0.05 12.3 6.0 0.066 11.9 4.2 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Nucleoplasmin PF03066.10 ETO13994.1 - 0.056 12.9 11.6 0.085 12.3 8.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin DUF2457 PF10446.4 ETO13994.1 - 0.12 11.1 10.1 0.15 10.7 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CobT PF06213.7 ETO13994.1 - 0.26 10.3 8.9 0.33 10.0 6.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Daxx PF03344.10 ETO13994.1 - 0.3 9.5 11.0 0.38 9.1 7.6 1.1 1 0 0 1 1 1 0 Daxx Family Sporozoite_P67 PF05642.6 ETO13994.1 - 0.55 8.0 2.1 0.63 7.8 1.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sigma70_ner PF04546.8 ETO13994.1 - 0.66 9.5 8.9 1.2 8.7 6.2 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region BSP_II PF05432.6 ETO13994.1 - 0.66 9.1 16.5 0.95 8.6 11.5 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TRAP_alpha PF03896.11 ETO13994.1 - 2.9 6.8 7.4 4.2 6.2 5.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit TFIIA PF03153.8 ETO13994.1 - 3.9 7.2 8.3 5.2 6.8 5.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit S-antigen PF05756.6 ETO13994.1 - 5.1 7.1 9.4 12 5.9 6.5 1.6 1 0 0 1 1 1 0 S-antigen protein Pox_Ag35 PF03286.9 ETO13994.1 - 5.2 6.5 9.0 8 5.9 6.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein ANAPC15 PF15243.1 ETO13994.1 - 5.4 7.1 16.6 10 6.2 11.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Adeno_terminal PF02459.10 ETO13994.1 - 5.6 5.0 6.2 7.5 4.5 4.3 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein DUF1510 PF07423.6 ETO13994.1 - 6.9 5.9 12.5 15 4.8 8.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1510) RGS PF00615.14 ETO13995.1 - 3.6e-08 33.5 3.9 2.3e-07 30.9 2.7 2.1 1 1 0 1 1 1 1 Regulator of G protein signaling domain Zip PF02535.17 ETO13995.1 - 0.02 13.9 0.0 0.028 13.4 0.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Vfa1 PF08432.5 ETO13995.1 - 0.077 13.0 2.5 0.14 12.2 1.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Sporozoite_P67 PF05642.6 ETO13995.1 - 1 7.1 7.4 1.5 6.6 5.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.7 ETO13995.1 - 4.3 6.5 14.0 6.7 5.8 9.7 1.2 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.4 ETO13995.1 - 7.2 5.2 21.4 11 4.6 14.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) 7TM-7TMR_HD PF07698.6 ETO13996.1 - 0.051 13.0 0.1 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase cNMP_binding PF00027.24 ETO13997.1 - 3.6e-17 61.9 0.0 1e-15 57.2 0.0 2.4 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Pkinase PF00069.20 ETO13997.1 - 9.1e-05 21.7 0.0 0.00018 20.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain G0-G1_switch_2 PF15103.1 ETO13997.1 - 0.0041 17.3 0.3 0.015 15.4 0.1 2.0 2 0 0 2 2 2 1 G0/G1 switch protein 2 DUF2203 PF09969.4 ETO13997.1 - 0.091 12.9 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) cNMP_binding PF00027.24 ETO13998.1 - 1e-26 92.5 0.4 4e-13 48.9 0.1 3.0 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Baculo_p24 PF05073.7 ETO14000.1 - 0.093 12.2 0.1 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Baculovirus P24 capsid protein ATP_synt_I PF03899.10 ETO14000.1 - 2 8.6 11.2 5.2 7.3 0.2 3.5 3 0 0 3 3 3 0 ATP synthase I chain RIO1 PF01163.17 ETO14001.1 - 3.3e-21 75.5 2.6 3.3e-21 75.5 1.8 3.3 3 1 0 3 3 3 1 RIO1 family DUF2164 PF09932.4 ETO14001.1 - 0.0046 16.7 0.1 0.024 14.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2164) Nop14 PF04147.7 ETO14001.1 - 0.65 7.8 52.9 0.015 13.2 9.9 2.2 2 0 0 2 2 2 0 Nop14-like family Myb_DNA-binding PF00249.26 ETO14002.1 - 7e-09 35.6 0.3 9.7e-09 35.1 0.2 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 ETO14002.1 - 1.1e-05 25.3 1.0 1.9e-05 24.6 0.7 1.5 1 1 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 ETO14002.1 - 0.00053 19.4 0.6 0.00091 18.7 0.4 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type TcdB_N PF12918.2 ETO14002.1 - 0.13 12.3 2.1 0.15 12.1 0.4 1.9 1 1 1 2 2 2 0 TcdB toxin N-terminal helical domain zf-B_box PF00643.19 ETO14002.1 - 2.6 8.0 6.5 0.63 9.9 1.7 1.9 2 0 0 2 2 2 0 B-box zinc finger zf-UBP PF02148.14 ETO14002.1 - 4.4 7.4 7.1 1.4 9.0 2.8 1.9 2 1 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein CCDC142 PF14923.1 ETO14003.1 - 0.03 12.6 0.0 0.049 11.9 0.0 1.3 1 0 0 1 1 1 0 Coiled-coil protein 142 GCIP PF13324.1 ETO14003.1 - 0.17 11.0 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting FlgI PF02119.11 ETO14004.1 - 0.033 12.8 0.1 0.056 12.0 0.1 1.3 1 0 0 1 1 1 0 Flagellar P-ring protein PH PF00169.24 ETO14005.1 - 8.1e-10 38.8 12.0 3e-05 24.1 0.1 3.4 3 1 0 3 3 3 2 PH domain PMSR PF01625.16 ETO14008.1 - 0.0032 17.3 0.1 0.011 15.6 0.0 1.7 2 0 0 2 2 2 1 Peptide methionine sulfoxide reductase Arch_ATPase PF01637.13 ETO14009.1 - 2.8e-05 23.9 6.3 3e-05 23.8 3.2 1.9 2 0 0 2 2 2 1 Archaeal ATPase AAA_14 PF13173.1 ETO14009.1 - 0.00028 20.7 4.3 0.00053 19.8 1.7 2.4 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 ETO14009.1 - 0.00056 20.2 0.9 0.0019 18.5 0.3 2.1 2 0 0 2 2 2 1 ABC transporter DUF2252 PF10009.4 ETO14009.1 - 0.0027 16.6 2.9 0.0046 15.8 2.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2252) AAA_28 PF13521.1 ETO14009.1 - 0.0033 17.3 0.3 0.08 12.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETO14009.1 - 0.0049 17.0 0.1 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 ETO14009.1 - 0.017 15.5 2.7 0.03 14.8 1.0 2.1 2 0 0 2 2 2 0 Miro-like protein PduV-EutP PF10662.4 ETO14009.1 - 0.019 14.4 0.0 0.071 12.5 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 ETO14009.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF1950 PF09187.5 ETO14009.1 - 0.1 12.7 0.3 0.37 10.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function(DUF1950) AAA_5 PF07728.9 ETO14009.1 - 0.22 11.2 3.0 1 9.0 2.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 ETO14009.1 - 0.29 11.3 7.1 0.74 10.0 4.1 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF1682 PF07946.9 ETO14009.1 - 0.41 9.4 16.7 0.72 8.6 11.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DDHD PF02862.12 ETO14009.1 - 0.44 10.3 3.4 0.96 9.1 2.4 1.5 1 0 0 1 1 1 0 DDHD domain FmdE PF02663.9 ETO14009.1 - 1.3 8.9 7.1 1.4 8.8 2.2 2.5 2 0 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Chromo PF00385.19 ETO14010.1 - 1.9e-10 40.2 0.9 1.9e-10 40.2 0.6 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Phospholip_A2_3 PF09056.6 ETO14012.1 - 0.045 13.9 1.6 0.067 13.4 0.1 2.1 2 1 0 2 2 2 0 Prokaryotic phospholipase A2 DUF1546 PF07571.8 ETO14012.1 - 0.055 13.5 0.0 0.64 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) Cyt-b5 PF00173.23 ETO14013.1 - 4.6e-26 90.4 0.0 6.6e-26 89.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MobB PF03205.9 ETO14015.1 - 4.1e-12 46.0 0.0 2.8e-11 43.2 0.0 2.3 2 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 ETO14015.1 - 0.00087 20.1 0.0 0.0019 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 ETO14015.1 - 0.0021 17.4 0.1 0.0049 16.3 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 ETO14015.1 - 0.0038 17.1 0.0 0.0061 16.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 ETO14015.1 - 0.0044 17.3 0.1 0.012 15.8 0.0 1.7 1 1 1 2 2 2 1 ABC transporter FtsK_SpoIIIE PF01580.13 ETO14015.1 - 0.017 14.6 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF87 PF01935.12 ETO14015.1 - 0.021 14.6 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_29 PF13555.1 ETO14015.1 - 0.029 13.8 0.0 0.063 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.15 ETO14015.1 - 0.058 12.0 0.3 0.076 11.6 0.2 1.1 1 0 0 1 1 1 0 G-protein alpha subunit AAA_16 PF13191.1 ETO14015.1 - 0.06 13.3 0.0 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 ETO14015.1 - 0.076 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 ETO14015.1 - 0.079 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 ETO14015.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.17 ETO14015.1 - 0.14 12.3 0.0 0.35 11.0 0.0 1.7 2 0 0 2 2 1 0 RNA helicase AAA_23 PF13476.1 ETO14015.1 - 0.14 12.4 4.4 0.4 10.9 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 ETO14015.1 - 0.14 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Tudor-knot PF11717.3 ETO14017.1 - 0.055 13.1 0.8 0.12 12.1 0.6 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain MBT PF02820.13 ETO14017.1 - 0.069 13.0 0.2 0.14 12.0 0.2 1.6 1 0 0 1 1 1 0 mbt repeat SR-25 PF10500.4 ETO14019.1 - 0.0027 17.2 9.6 0.0027 17.2 6.7 3.2 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein DUF1700 PF08006.6 ETO14020.1 - 0.0077 15.5 0.6 0.012 14.8 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1700) DUF1104 PF06518.6 ETO14020.1 - 0.13 12.4 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) UCH PF00443.24 ETO14021.1 - 8.8e-38 129.9 6.6 8.8e-38 129.9 4.6 3.4 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO14021.1 - 5.9e-29 101.4 3.6 5.9e-29 101.4 2.5 2.8 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase EF-hand_6 PF13405.1 ETO14021.1 - 0.011 15.5 0.1 0.082 12.8 0.1 2.6 1 0 0 1 1 1 0 EF-hand domain ANAPC15 PF15243.1 ETO14023.1 - 0.0011 19.0 3.6 0.0011 18.9 2.5 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 15 BSP_II PF05432.6 ETO14023.1 - 0.0017 17.6 4.6 0.0019 17.5 3.2 1.0 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Nucleoplasmin PF03066.10 ETO14023.1 - 0.0022 17.5 8.0 0.0024 17.3 5.5 1.1 1 0 0 1 1 1 1 Nucleoplasmin DUF1510 PF07423.6 ETO14023.1 - 0.0033 16.8 0.7 0.0038 16.6 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) TRAP_alpha PF03896.11 ETO14023.1 - 0.035 13.1 3.0 0.034 13.1 2.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FAM176 PF14851.1 ETO14023.1 - 0.04 13.6 1.4 0.044 13.4 1.0 1.2 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.5 ETO14023.1 - 0.042 14.0 14.4 0.052 13.7 10.0 1.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Hus1 PF04005.7 ETO14023.1 - 0.051 12.5 0.1 0.055 12.3 0.1 1.0 1 0 0 1 1 1 0 Hus1-like protein DUF4484 PF14831.1 ETO14023.1 - 0.053 13.6 3.1 0.054 13.6 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Prog_receptor PF02161.10 ETO14023.1 - 0.071 11.9 0.3 0.069 11.9 0.2 1.0 1 0 0 1 1 1 0 Progesterone receptor HSP90 PF00183.13 ETO14023.1 - 0.089 11.1 2.4 0.089 11.1 1.7 1.0 1 0 0 1 1 1 0 Hsp90 protein Bd3614_N PF14442.1 ETO14023.1 - 0.14 12.1 3.5 0.15 12.0 2.4 1.1 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal Sporozoite_P67 PF05642.6 ETO14023.1 - 0.2 9.5 1.7 0.19 9.5 1.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RRN3 PF05327.6 ETO14023.1 - 0.23 9.5 1.7 0.21 9.6 1.2 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CobT PF06213.7 ETO14023.1 - 0.34 10.0 11.0 0.4 9.7 7.6 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sigma70_ner PF04546.8 ETO14023.1 - 0.51 9.9 10.2 0.59 9.7 7.0 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Pox_Ag35 PF03286.9 ETO14023.1 - 0.55 9.7 8.2 0.65 9.4 5.7 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NOA36 PF06524.7 ETO14023.1 - 0.59 9.3 10.9 0.67 9.1 7.5 1.0 1 0 0 1 1 1 0 NOA36 protein Pox_RNA_Pol_19 PF05320.7 ETO14023.1 - 0.79 9.4 6.8 0.92 9.2 4.7 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF2457 PF10446.4 ETO14023.1 - 1.2 7.8 18.3 1.3 7.6 12.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RXT2_N PF08595.6 ETO14023.1 - 2.1 8.1 10.3 2.7 7.7 7.1 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal Paf1 PF03985.8 ETO14023.1 - 2.4 6.7 7.5 2.8 6.6 5.2 1.0 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.9 ETO14023.1 - 3.7 5.4 7.9 4.3 5.2 5.5 1.0 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.8 ETO14023.1 - 4.8 4.8 17.5 5.2 4.7 12.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi PBP1_TM PF14812.1 ETO14023.1 - 5.4 7.3 12.0 8.9 6.7 8.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal eIF-3c_N PF05470.7 ETO14023.1 - 5.4 4.9 6.4 6.2 4.7 4.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus BUD22 PF09073.5 ETO14023.1 - 7.8 5.4 10.5 9.1 5.2 7.3 1.0 1 0 0 1 1 1 0 BUD22 Dicty_REP PF05086.7 ETO14023.1 - 9 3.9 8.9 10 3.7 6.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pex14_N PF04695.8 ETO14024.1 - 0.26 11.3 3.8 0.41 10.6 2.6 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Menin PF05053.8 ETO14024.1 - 0.5 8.4 6.3 0.57 8.2 4.4 1.1 1 0 0 1 1 1 0 Menin Apc15p PF05841.6 ETO14024.1 - 1.5 9.5 13.3 2.5 8.8 9.3 1.3 1 0 0 1 1 1 0 Apc15p protein DUF912 PF06024.7 ETO14024.1 - 4.8 7.3 10.6 12 6.0 7.3 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3439 PF11921.3 ETO14025.1 - 0.16 11.6 19.3 0.4 10.4 13.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Med3 PF11593.3 ETO14025.1 - 0.2 10.8 16.9 0.37 9.9 11.7 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TFIIA PF03153.8 ETO14026.1 - 0.00074 19.5 27.1 0.00074 19.5 18.8 2.3 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Sec16 PF12932.2 ETO14026.1 - 3.2 7.7 10.0 3.1 7.7 1.4 3.0 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region MIP-T3 PF10243.4 ETO14027.1 - 0.087 11.2 19.8 0.1 11.0 13.7 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Sporozoite_P67 PF05642.6 ETO14027.1 - 0.16 9.7 5.4 0.25 9.1 3.7 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MSP1_C PF07462.6 ETO14028.1 - 0.26 9.6 3.6 0.3 9.4 2.5 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus TMEM154 PF15102.1 ETO14028.1 - 1.6 8.4 6.7 4.1 7.1 4.7 1.7 1 0 0 1 1 1 0 TMEM154 protein family CBFD_NFYB_HMF PF00808.18 ETO14029.1 - 1.1e-13 50.9 0.4 2.8e-13 49.7 0.3 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HMG_box PF00505.14 ETO14029.1 - 3.8e-10 39.8 2.3 6.8e-10 39.0 0.3 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box Histone PF00125.19 ETO14029.1 - 5.1e-09 36.1 0.1 8.4e-09 35.4 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 HMG_box_2 PF09011.5 ETO14029.1 - 1.3e-05 25.4 1.9 3.1e-05 24.2 1.3 1.7 1 0 0 1 1 1 1 HMG-box domain WD40 PF00400.27 ETO14030.1 - 1.1e-56 186.7 23.9 2.9e-10 39.6 0.4 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO14030.1 - 1.9e-07 29.6 6.3 0.0013 16.9 0.1 5.3 1 1 2 4 4 4 3 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO14030.1 - 3.2e-05 24.2 2.9 3.2e-05 24.2 2.0 3.0 3 0 0 3 3 3 1 TRAF-type zinc finger Ras PF00071.17 ETO14031.1 - 4.3e-24 84.7 0.1 7.6e-24 83.9 0.1 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO14031.1 - 2e-06 28.2 0.1 4.3e-06 27.2 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO14031.1 - 7.9e-05 21.9 0.1 0.00012 21.3 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETO14031.1 - 9.8e-05 22.2 0.0 0.00028 20.7 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 ETO14031.1 - 0.052 12.6 0.3 0.13 11.3 0.0 1.7 1 1 1 2 2 2 0 Gtr1/RagA G protein conserved region Ras PF00071.17 ETO14032.1 - 4.1e-15 55.5 0.2 2.3e-14 53.1 0.1 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 ETO14032.1 - 6.9e-05 23.3 0.1 0.0002 21.8 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Yippee-Mis18 PF03226.9 ETO14033.1 - 7.9e-11 41.8 0.6 7.9e-11 41.8 0.4 2.3 2 1 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Filament PF00038.16 ETO14033.1 - 0.00047 19.7 10.1 0.00067 19.2 7.0 1.2 1 0 0 1 1 1 1 Intermediate filament protein Med3 PF11593.3 ETO14033.1 - 0.00086 18.6 7.8 0.0011 18.2 5.4 1.2 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal GFA PF04828.9 ETO14033.1 - 0.0048 16.8 7.4 0.1 12.5 0.1 3.4 2 2 1 4 4 4 2 Glutathione-dependent formaldehyde-activating enzyme V_ATPase_I PF01496.14 ETO14033.1 - 0.016 13.1 6.8 0.018 12.9 4.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HrcA PF01628.16 ETO14033.1 - 0.026 14.1 2.9 0.037 13.6 2.0 1.2 1 0 0 1 1 1 0 HrcA protein C terminal domain Lebercilin PF15619.1 ETO14033.1 - 0.028 13.8 13.9 0.047 13.1 9.6 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease C1_4 PF07975.7 ETO14033.1 - 0.072 13.1 1.6 0.2 11.6 0.1 2.4 2 0 0 2 2 2 0 TFIIH C1-like domain APG6 PF04111.7 ETO14033.1 - 0.1 11.6 19.0 0.47 9.4 7.8 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF2982 PF11201.3 ETO14033.1 - 0.19 11.0 2.0 0.34 10.2 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2982) LURAP PF14854.1 ETO14033.1 - 0.22 11.2 6.1 0.28 10.9 3.6 1.8 1 1 0 1 1 1 0 Leucine rich adaptor protein DUF342 PF03961.8 ETO14033.1 - 0.38 9.1 9.7 0.57 8.5 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TBPIP PF07106.8 ETO14033.1 - 0.58 9.6 19.0 0.092 12.2 7.0 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DASH_Dad3 PF08656.5 ETO14033.1 - 0.6 9.8 7.3 0.3 10.8 1.1 2.8 1 1 2 3 3 3 0 DASH complex subunit Dad3 zf-C4H2 PF10146.4 ETO14033.1 - 0.64 10.0 12.4 1.2 9.1 8.6 1.4 1 1 0 1 1 1 0 Zinc finger-containing protein Spc7 PF08317.6 ETO14033.1 - 0.87 8.1 16.8 1.7 7.1 11.6 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.3 ETO14033.1 - 1.5 8.5 17.0 0.19 11.4 6.1 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Syntaxin-6_N PF09177.6 ETO14033.1 - 2.6 8.4 9.8 6.4 7.2 5.3 2.5 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DUF2407_C PF13373.1 ETO14033.1 - 2.9 7.8 6.8 4 7.3 1.5 2.6 1 1 2 3 3 3 0 DUF2407 C-terminal domain GAS PF13851.1 ETO14033.1 - 3.2 6.9 19.8 3.5 6.7 7.3 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding BRE1 PF08647.6 ETO14033.1 - 4.8 7.2 19.3 0.21 11.6 7.4 2.7 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase Enkurin PF13864.1 ETO14033.1 - 9.6 6.4 16.2 40 4.4 2.7 3.1 1 1 1 2 2 2 0 Calmodulin-binding DUF2189 PF09955.4 ETO14036.1 - 0.031 14.1 0.2 0.049 13.5 0.1 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2189) LRR19-TM PF15176.1 ETO14036.1 - 0.17 11.5 3.9 0.45 10.2 0.1 2.2 1 1 1 2 2 2 0 Leucine-rich repeat family 19 TM domain DUF1673 PF07895.6 ETO14036.1 - 0.55 9.7 8.4 1.5 8.2 5.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) NPCC PF08058.6 ETO14036.1 - 7.9 6.3 7.9 7.4 6.4 3.8 1.9 2 0 0 2 2 2 0 Nuclear pore complex component SAP PF02037.22 ETO14037.1 - 2.7e-05 23.5 0.2 0.0001 21.6 0.0 2.1 2 0 0 2 2 2 1 SAP domain LMBR1 PF04791.11 ETO14039.1 - 0.098 11.2 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein CDC45 PF02724.9 ETO14039.1 - 0.47 8.4 11.5 0.63 8.0 8.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Sec62 PF03839.11 ETO14039.1 - 1.3 8.4 6.7 2.4 7.5 4.7 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Transaldolase PF00923.14 ETO14040.1 - 7.5e-82 274.6 0.5 9.1e-82 274.4 0.4 1.0 1 0 0 1 1 1 1 Transaldolase Interferon PF00143.14 ETO14042.1 - 0.052 13.4 1.4 0.19 11.5 0.2 1.9 1 1 1 2 2 2 0 Interferon alpha/beta domain BRO1 PF03097.13 ETO14042.1 - 0.053 12.2 2.2 0.055 12.2 1.5 1.0 1 0 0 1 1 1 0 BRO1-like domain Flagellin_N PF00669.15 ETO14042.1 - 0.49 10.1 3.7 0.35 10.6 1.0 1.8 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region DUF2408 PF10303.4 ETO14042.1 - 1 9.4 5.8 0.79 9.8 1.2 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2408) Helicase_C PF00271.26 ETO14043.1 - 6.2e-28 96.4 0.3 8.9e-28 95.9 0.2 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain tRNA-synt_1b PF00579.20 ETO14043.1 - 0.026 13.6 0.0 0.027 13.6 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) RRM_1 PF00076.17 ETO14044.1 - 0.0013 18.3 0.2 0.0022 17.5 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO14044.1 - 0.0035 17.2 0.0 0.0064 16.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 ETO14044.1 - 0.025 13.0 23.1 0.033 12.6 16.0 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF4629 PF15442.1 ETO14044.1 - 0.31 11.1 5.4 0.49 10.5 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) DUF1777 PF08648.7 ETO14044.1 - 1.6 8.4 83.3 6.6 6.4 38.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1777) PA28_beta PF02252.13 ETO14045.1 - 2.3e-31 108.3 1.5 2.8e-31 108.0 0.5 1.6 1 1 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.13 ETO14045.1 - 0.00092 19.3 0.6 0.00092 19.3 0.4 2.3 3 1 0 3 3 3 1 Proteasome activator pa28 alpha subunit V_ATPase_I PF01496.14 ETO14045.1 - 0.0051 14.7 2.8 0.0063 14.4 2.0 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF771 PF05595.6 ETO14045.1 - 0.012 15.4 2.4 0.028 14.3 1.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF771) YusW PF14039.1 ETO14045.1 - 0.036 14.3 0.7 0.083 13.1 0.5 1.7 1 0 0 1 1 1 0 YusW-like protein Apolipoprotein PF01442.13 ETO14045.1 - 0.18 11.2 3.0 0.31 10.5 2.1 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain IncA PF04156.9 ETO14045.1 - 2 7.9 9.8 0.39 10.2 3.9 1.8 2 0 0 2 2 2 0 IncA protein TPR_12 PF13424.1 ETO14046.1 - 5.3e-244 788.9 31.1 3.3e-26 91.0 0.2 9.8 3 1 8 12 12 12 12 Tetratricopeptide repeat TPR_10 PF13374.1 ETO14046.1 - 2.7e-128 414.7 0.0 1.4e-09 37.5 0.0 16.1 15 1 1 16 16 16 14 Tetratricopeptide repeat TPR_1 PF00515.23 ETO14046.1 - 2.1e-114 368.9 84.3 9.2e-09 34.5 0.7 16.6 16 1 1 17 17 16 16 Tetratricopeptide repeat TPR_11 PF13414.1 ETO14046.1 - 1.4e-113 370.6 33.3 2.4e-15 55.9 0.2 9.6 6 2 4 10 10 10 10 TPR repeat TPR_7 PF13176.1 ETO14046.1 - 2.1e-111 355.1 18.6 2.1e-07 30.2 0.0 16.3 15 1 1 16 16 16 16 Tetratricopeptide repeat TPR_2 PF07719.12 ETO14046.1 - 3.7e-84 270.0 54.4 1e-06 28.1 0.2 16.5 15 1 1 16 16 16 16 Tetratricopeptide repeat TPR_8 PF13181.1 ETO14046.1 - 1e-77 250.2 108.5 1.6e-07 30.5 1.6 16.5 15 1 1 16 16 16 16 Tetratricopeptide repeat TPR_17 PF13431.1 ETO14046.1 - 2.5e-58 189.4 20.5 0.0023 17.9 0.0 16.2 15 1 0 15 15 15 14 Tetratricopeptide repeat TPR_16 PF13432.1 ETO14046.1 - 9e-46 153.6 0.0 8e-06 26.3 0.0 9.8 7 2 4 11 11 10 9 Tetratricopeptide repeat TPR_14 PF13428.1 ETO14046.1 - 4.7e-30 101.3 0.0 0.21 12.3 0.0 15.1 9 6 7 16 16 15 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO14046.1 - 3.1e-25 88.3 0.7 0.031 14.6 0.0 10.4 5 3 8 13 13 13 7 Tetratricopeptide repeat Apc3 PF12895.2 ETO14046.1 - 2.2e-23 82.2 39.1 1e-05 25.5 1.7 9.6 1 1 9 11 11 11 8 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETO14046.1 - 2.8e-20 71.3 16.6 0.11 13.0 0.0 14.4 15 0 0 15 15 15 2 Tetratricopeptide repeat PPR PF01535.15 ETO14046.1 - 1e-15 56.5 43.0 0.4 10.7 0.0 15.8 16 0 0 16 16 16 2 PPR repeat MIT PF04212.13 ETO14046.1 - 8.3e-10 38.4 53.7 0.076 12.9 0.3 14.4 14 1 1 15 15 15 4 MIT (microtubule interacting and transport) domain DUF627 PF04781.7 ETO14046.1 - 2.4e-09 36.7 24.0 0.4 10.3 0.0 11.0 9 3 2 11 11 9 3 Protein of unknown function (DUF627) RPN7 PF10602.4 ETO14046.1 - 1.6e-06 27.6 38.7 1.2 8.4 0.1 12.1 6 4 5 12 12 12 3 26S proteasome subunit RPN7 Ten1_2 PF15490.1 ETO14046.1 - 1.7e-06 27.5 0.0 46 3.6 0.0 7.8 3 1 5 10 10 10 0 Telomere-capping, CST complex subunit Musclin PF11037.3 ETO14046.1 - 0.00012 21.7 0.0 12 5.5 0.0 6.5 8 0 0 8 8 6 0 Insulin-resistance promoting peptide in skeletal muscle TPR_5 PF12688.2 ETO14046.1 - 0.00013 21.9 3.6 1.2 9.1 0.0 6.1 7 1 0 7 7 5 1 Tetratrico peptide repeat Sel1 PF08238.7 ETO14046.1 - 0.00019 21.9 36.6 2.5 8.8 0.1 11.1 14 0 0 14 14 10 2 Sel1 repeat TPR_21 PF09976.4 ETO14046.1 - 0.0012 18.7 6.8 1.7 8.6 0.1 6.0 6 1 1 7 7 6 1 Tetratricopeptide repeat Rab5-bind PF09311.6 ETO14046.1 - 0.0075 16.1 0.1 0.36 10.6 0.0 3.7 5 0 0 5 5 4 1 Rabaptin-like protein Clathrin PF00637.15 ETO14046.1 - 0.055 13.0 32.2 1.4 8.5 0.5 8.3 3 3 2 7 7 7 0 Region in Clathrin and VPS FATC PF02260.15 ETO14046.1 - 0.14 11.5 6.6 8.4 5.9 0.1 5.8 7 0 0 7 7 6 0 FATC domain Fis1_TPR_C PF14853.1 ETO14046.1 - 1.2 9.0 40.8 8.3 6.3 0.3 11.3 12 0 0 12 12 11 0 Fis1 C-terminal tetratricopeptide repeat DUF3450 PF11932.3 ETO14046.1 - 2.1 7.5 13.0 0.82 8.8 0.1 5.1 5 1 1 6 6 6 0 Protein of unknown function (DUF3450) TPR_3 PF07720.7 ETO14046.1 - 8.9 6.2 66.4 0.18 11.6 0.8 12.7 16 0 0 16 16 14 0 Tetratricopeptide repeat WD40 PF00400.27 ETO14047.1 - 9.3e-21 72.8 3.9 5e-08 32.5 0.0 3.9 4 1 0 4 4 4 3 WD domain, G-beta repeat RimK PF08443.6 ETO14048.1 - 6e-34 117.1 0.0 5.7e-33 113.9 0.0 2.2 2 0 0 2 2 2 1 RimK-like ATP-grasp domain GSH-S_ATP PF02955.11 ETO14048.1 - 1.1e-12 47.4 0.0 2e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_4 PF13535.1 ETO14048.1 - 8.6e-05 22.3 0.0 0.0032 17.2 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain CDO_I PF05995.7 ETO14048.1 - 0.024 13.8 0.0 0.053 12.7 0.0 1.5 1 0 0 1 1 1 0 Cysteine dioxygenase type I TMEM154 PF15102.1 ETO14049.1 - 8e-07 28.8 4.0 1.3e-06 28.1 2.8 1.3 1 0 0 1 1 1 1 TMEM154 protein family DUF912 PF06024.7 ETO14049.1 - 9.2e-06 25.6 5.0 1.7e-05 24.8 3.4 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Rifin_STEVOR PF02009.11 ETO14049.1 - 0.00022 20.9 4.0 0.00031 20.5 2.8 1.2 1 0 0 1 1 1 1 Rifin/stevor family DUF1183 PF06682.7 ETO14049.1 - 0.00049 19.7 0.1 0.00078 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) DUF4448 PF14610.1 ETO14049.1 - 0.00067 19.2 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) EVI2A PF05399.6 ETO14049.1 - 0.001 18.3 2.2 0.0014 17.8 1.5 1.2 1 0 0 1 1 1 1 Ectropic viral integration site 2A protein (EVI2A) ATG27 PF09451.5 ETO14049.1 - 0.0013 18.0 1.5 0.0027 16.9 1.0 1.5 1 1 1 2 2 2 1 Autophagy-related protein 27 DUF2207 PF09972.4 ETO14049.1 - 0.0019 16.9 0.2 0.0025 16.4 0.2 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Herpes_gE PF02480.11 ETO14049.1 - 0.0068 14.7 0.0 0.0093 14.2 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Shisa PF13908.1 ETO14049.1 - 0.0083 16.3 3.6 0.013 15.6 2.5 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator LRRC37AB_C PF14914.1 ETO14049.1 - 0.011 15.2 1.7 0.016 14.6 1.2 1.3 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Mid2 PF04478.7 ETO14049.1 - 0.011 15.1 6.6 0.021 14.2 4.6 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DAG1 PF05454.6 ETO14049.1 - 0.022 13.9 1.5 0.047 12.8 0.8 1.6 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) EssA PF10661.4 ETO14049.1 - 0.031 13.9 1.3 0.047 13.3 0.9 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA DUF3377 PF11857.3 ETO14049.1 - 0.067 12.8 1.2 0.12 11.9 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Vma12 PF11712.3 ETO14049.1 - 0.071 12.8 0.5 0.11 12.1 0.3 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Glycophorin_A PF01102.13 ETO14049.1 - 0.071 12.8 0.9 0.11 12.2 0.7 1.3 1 0 0 1 1 1 0 Glycophorin A GP41 PF00517.12 ETO14049.1 - 0.072 12.6 4.0 0.11 12.0 2.8 1.3 1 0 0 1 1 1 0 Retroviral envelope protein Baculo_E56 PF04639.7 ETO14049.1 - 0.075 11.6 6.9 0.12 11.0 4.8 1.2 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope Protocadherin PF08374.6 ETO14049.1 - 0.078 12.6 3.2 0.12 11.9 2.2 1.3 1 0 0 1 1 1 0 Protocadherin SKN1 PF03935.10 ETO14049.1 - 0.11 10.6 0.4 0.16 10.1 0.3 1.1 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) EMP24_GP25L PF01105.19 ETO14049.1 - 0.15 11.7 2.3 0.2 11.3 1.6 1.4 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Marek_A PF02124.10 ETO14049.1 - 0.23 10.9 0.9 0.35 10.2 0.6 1.2 1 0 0 1 1 1 0 Marek's disease glycoprotein A Plant_vir_prot PF01307.12 ETO14049.1 - 4.9 6.9 6.0 30 4.3 3.3 2.5 2 1 0 2 2 1 0 Plant viral movement protein Baculo_11_kDa PF06143.6 ETO14049.1 - 7.5 5.9 13.4 18 4.7 9.3 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family ASFV_J13L PF05568.6 ETO14049.1 - 7.5 6.0 14.8 16 4.9 10.3 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein ATP-grasp_3 PF02655.9 ETO14051.1 - 1 9.2 5.7 0.37 10.6 0.7 2.6 2 1 1 3 3 3 0 ATP-grasp domain PH PF00169.24 ETO14052.1 - 1.3e-07 31.7 0.2 1.3e-07 31.7 0.2 2.5 2 1 0 2 2 2 1 PH domain PH_11 PF15413.1 ETO14052.1 - 0.0017 18.6 0.2 0.0017 18.6 0.1 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain Mcp5_PH PF12814.2 ETO14052.1 - 0.0045 16.9 0.2 0.0045 16.9 0.1 2.8 2 1 1 3 3 3 2 Meiotic cell cortex C-terminal pleckstrin homology DUF3504 PF12012.3 ETO14052.1 - 1.8 8.3 7.7 0.17 11.6 1.7 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF3504) PDCD2_C PF04194.8 ETO14053.1 - 6.3e-17 61.6 0.7 6.3e-17 61.6 0.5 2.8 3 1 1 4 4 4 1 Programmed cell death protein 2, C-terminal putative domain PSCyt3 PF07627.6 ETO14053.1 - 0.011 15.5 1.4 0.037 13.8 1.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) CENP-B_dimeris PF09026.5 ETO14054.1 - 0.11 12.7 5.9 0.22 11.7 4.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TRAP_alpha PF03896.11 ETO14054.1 - 0.12 11.3 2.7 0.16 10.9 1.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Vpu PF00558.14 ETO14054.1 - 0.27 10.8 4.1 0.58 9.7 2.9 1.6 1 0 0 1 1 1 0 Vpu protein RXT2_N PF08595.6 ETO14054.1 - 0.3 10.8 7.4 0.04 13.7 2.1 1.7 2 0 0 2 2 2 0 RXT2-like, N-terminal FAM176 PF14851.1 ETO14054.1 - 0.49 10.0 7.4 0.85 9.2 5.1 1.3 1 0 0 1 1 1 0 FAM176 family Myc_N PF01056.13 ETO14054.1 - 2.3 7.2 7.8 3.5 6.7 5.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF4337 PF14235.1 ETO14054.1 - 2.5 7.9 6.1 3.9 7.2 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) YqfQ PF14181.1 ETO14054.1 - 9.4 6.2 9.0 8.7 6.3 4.8 1.9 2 0 0 2 2 2 0 YqfQ-like protein GAS PF13851.1 ETO14055.1 - 0.0045 16.2 21.8 0.0045 16.2 15.1 5.4 1 1 4 6 6 6 1 Growth-arrest specific micro-tubule binding SAD_SRA PF02182.12 ETO14057.1 - 0.38 10.0 2.4 0.25 10.6 0.1 1.8 2 0 0 2 2 2 0 SAD/SRA domain Zip PF02535.17 ETO14058.1 - 2.9 6.8 19.9 5.4 5.9 13.8 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter SAM_1 PF00536.25 ETO14059.1 - 4.2e-21 74.8 3.5 3.5e-11 43.1 0.2 2.8 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO14059.1 - 9.5e-20 70.2 2.3 4e-09 36.1 0.1 2.8 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) DUF3298 PF11738.3 ETO14059.1 - 1.1 9.8 4.1 0.78 10.2 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3298) CotJB PF12652.2 ETO14059.1 - 6.9 6.8 15.2 1.1 9.3 1.4 4.8 3 1 2 5 5 5 0 CotJB protein UCH PF00443.24 ETO14061.1 - 1.2 8.1 7.4 1.6 7.8 5.1 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Tyrosinase PF00264.15 ETO14062.1 - 0.98 9.5 7.9 0.41 10.7 3.3 1.7 1 1 1 2 2 2 0 Common central domain of tyrosinase Ras PF00071.17 ETO14063.1 - 2.5e-09 36.7 0.7 4.6e-09 35.8 0.5 1.5 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.22 ETO14063.1 - 0.039 13.3 0.1 0.056 12.8 0.1 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain chaperone_DMP PF10448.4 ETO14063.1 - 0.18 11.7 3.8 3.3 7.6 0.6 2.3 1 1 1 2 2 2 0 20S proteasome chaperone MIF4G PF02854.14 ETO14065.1 - 3e-09 36.5 1.5 3e-09 36.5 1.0 2.6 3 0 0 3 3 3 1 MIF4G domain PspB PF06667.7 ETO14065.1 - 0.23 11.4 0.1 0.23 11.4 0.1 2.4 3 0 0 3 3 3 0 Phage shock protein B Copper-bind PF00127.15 ETO14066.1 - 0.062 13.5 0.2 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family MHC_I PF00129.13 ETO14066.1 - 0.069 12.4 1.5 0.096 12.0 0.1 1.7 1 1 0 2 2 2 0 Class I Histocompatibility antigen, domains alpha 1 and 2 PPDFL PF15060.1 ETO14066.1 - 0.12 12.4 1.5 0.2 11.6 0.4 2.0 1 1 1 2 2 2 0 Differentiation and proliferation regulator RNase_H2_suC PF08615.6 ETO14067.1 - 1.1e-08 35.0 0.1 1.5e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) C9orf72-like PF15019.1 ETO14068.1 - 5.8e-17 61.7 0.1 2.4e-16 59.7 0.0 2.0 2 0 0 2 2 2 1 C9orf72-like protein family T_cell_tran_alt PF15128.1 ETO14068.1 - 0.02 14.3 0.4 0.04 13.3 0.3 1.4 1 0 0 1 1 1 0 T-cell leukemia translocation-altered Cnd2 PF05786.9 ETO14069.1 - 8e-54 183.3 4.4 1e-53 183.0 3.1 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 DUF3289 PF11692.3 ETO14069.1 - 0.018 14.3 0.6 0.031 13.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3289) Rad21_Rec8_N PF04825.8 ETO14069.1 - 0.021 14.7 0.1 0.049 13.5 0.1 1.7 1 0 0 1 1 1 0 N terminus of Rad21 / Rec8 like protein Cnd2 PF05786.9 ETO14070.1 - 7e-39 133.9 17.0 9.3e-39 133.5 11.8 1.3 1 0 0 1 1 1 1 Condensin complex subunit 2 AATF-Che1 PF13339.1 ETO14071.1 - 0.0029 17.7 1.8 0.0029 17.7 1.3 1.5 1 1 1 2 2 2 1 Apoptosis antagonizing transcription factor CENP-B_dimeris PF09026.5 ETO14071.1 - 0.0047 17.1 5.7 0.022 14.9 4.1 1.9 2 0 0 2 2 2 1 Centromere protein B dimerisation domain TFR_dimer PF04253.10 ETO14071.1 - 0.0064 16.0 1.4 0.03 13.8 0.1 2.2 2 1 0 2 2 2 1 Transferrin receptor-like dimerisation domain DUF382 PF04037.8 ETO14071.1 - 0.014 15.2 2.1 0.13 12.1 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF382) TPR_MLP1_2 PF07926.7 ETO14071.1 - 0.5 10.1 8.4 0.77 9.5 4.1 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein FAM176 PF14851.1 ETO14071.1 - 0.96 9.1 5.3 0.28 10.8 1.6 1.6 2 0 0 2 2 2 0 FAM176 family YqfQ PF14181.1 ETO14071.1 - 5.5 7.0 6.2 1.7 8.6 2.3 1.6 2 0 0 2 2 2 0 YqfQ-like protein zf-C3HC4_3 PF13920.1 ETO14072.1 - 1.9e-07 30.6 11.8 5.6e-07 29.1 8.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO14072.1 - 0.0011 18.9 13.3 0.0011 18.9 9.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO14072.1 - 0.2 11.3 12.8 0.68 9.6 8.9 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO14072.1 - 1.7 8.5 17.2 0.19 11.5 7.5 2.8 3 0 0 3 3 3 0 Ring finger domain BRCT PF00533.21 ETO14074.1 - 0.0027 17.8 7.0 0.37 10.9 0.0 3.0 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain DUF4492 PF14899.1 ETO14075.1 - 0.00087 18.7 0.3 0.0026 17.2 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4492) DUF1651 PF07864.6 ETO14075.1 - 0.02 14.9 0.2 0.09 12.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1651) CNPase PF05881.7 ETO14075.1 - 0.068 12.5 0.5 0.1 11.9 0.3 1.2 1 0 0 1 1 1 0 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) S_layer_N PF05123.7 ETO14075.1 - 0.09 12.3 2.2 0.11 12.1 1.5 1.0 1 0 0 1 1 1 0 S-layer like family, N-terminal region DUF3357 PF11837.3 ETO14075.1 - 0.13 12.1 0.3 0.57 10.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) EF-hand_1 PF00036.27 ETO14077.1 - 4.7e-17 59.9 7.8 5.4e-05 22.2 0.2 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 ETO14077.1 - 1.2e-16 60.5 6.2 1.3e-07 31.5 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO14077.1 - 2.9e-13 48.4 5.4 0.0006 19.4 0.4 4.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 ETO14077.1 - 7.1e-11 41.5 5.8 8e-06 25.3 0.4 4.2 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 ETO14077.1 - 0.00037 19.6 0.2 0.00037 19.6 0.1 3.9 4 1 0 4 4 4 1 EF hand EF-hand_4 PF12763.2 ETO14077.1 - 0.0042 16.8 5.8 1.3 8.8 0.0 3.7 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 ETO14077.1 - 0.0081 16.1 17.8 0.038 14.0 0.2 4.2 3 1 0 3 3 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 ETO14077.1 - 0.045 13.4 4.0 3.6 7.3 0.0 4.1 4 0 0 4 4 4 0 EF hand DUF948 PF06103.6 ETO14077.1 - 0.067 13.0 0.3 0.067 13.0 0.2 4.3 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) CENP-Q PF13094.1 ETO14077.1 - 0.85 9.6 47.8 0.34 10.9 10.2 4.2 3 2 1 4 4 4 0 CENP-Q, a CENPA-CAD centromere complex subunit DegQ PF08181.6 ETO14077.1 - 3.6 7.3 12.1 0.67 9.7 0.3 4.1 3 1 0 3 3 3 0 DegQ (SacQ) family DUF1664 PF07889.7 ETO14077.1 - 6.6 6.5 22.0 1.3 8.8 2.8 4.6 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) CppA_C PF14507.1 ETO14078.1 - 0.048 13.8 3.3 0.095 12.8 0.8 2.4 2 0 0 2 2 2 0 CppA C-terminal His_Phos_1 PF00300.17 ETO14079.1 - 7.8e-06 26.0 0.1 2.9e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Methyltransf_12 PF08242.7 ETO14079.1 - 0.41 11.1 8.2 3 8.3 1.0 2.9 2 0 0 2 2 2 0 Methyltransferase domain DUF3439 PF11921.3 ETO14079.1 - 0.58 9.9 13.5 2.4 7.9 9.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Ubiq_cyt_C_chap PF03981.7 ETO14080.1 - 1.6e-06 27.9 0.8 0.032 14.0 0.2 2.2 2 0 0 2 2 2 2 Ubiquinol-cytochrome C chaperone DUF3583 PF12126.3 ETO14080.1 - 1.2 8.1 4.8 1.9 7.4 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) DUF4120 PF13496.1 ETO14082.1 - 0.0034 17.3 1.2 0.0087 16.0 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4120) ATP-synt_B PF00430.13 ETO14082.1 - 0.25 11.1 8.8 0.5 10.1 6.1 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF2120 PF09893.4 ETO14082.1 - 1.5 8.7 6.3 15 5.4 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) UBX PF00789.15 ETO14083.1 - 1e-09 38.3 0.0 2.1e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 UBX domain Pyridoxal_deC PF00282.14 ETO14086.1 - 2.5e-07 29.4 0.1 1.6e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 ETO14086.1 - 0.00074 18.7 0.1 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase PUB PF09409.5 ETO14087.1 - 0.0019 17.9 0.5 0.0099 15.6 0.1 2.3 2 1 0 2 2 2 1 PUB domain CAP_GLY PF01302.20 ETO14089.1 - 6.1e-13 48.2 0.2 1.2e-12 47.2 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain DUF1673 PF07895.6 ETO14089.1 - 0.063 12.7 3.0 0.16 11.5 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) SPRR2 PF14820.1 ETO14089.1 - 0.68 9.8 7.2 5.4 6.9 0.2 3.8 2 1 1 3 3 3 0 Small proline-rich 2 Guanylate_cyc PF00211.15 ETO14090.1 - 1.3e-08 34.4 0.0 3e-08 33.2 0.0 1.6 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.1 ETO14090.1 - 7e-06 26.1 0.0 1e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain F420_oxidored PF03807.12 ETO14091.1 - 1.4e-12 47.8 0.6 2.3e-11 43.9 0.4 2.2 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 ETO14091.1 - 3.1e-10 40.1 0.1 4.4e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 ETO14091.1 - 0.00014 21.5 0.4 0.00032 20.4 0.3 1.5 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 ETO14091.1 - 0.00092 18.4 0.0 0.012 14.7 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NmrA PF05368.8 ETO14091.1 - 0.0021 17.3 0.1 0.0041 16.4 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family NAD_Gly3P_dh_N PF01210.18 ETO14091.1 - 0.0058 16.3 0.2 0.037 13.7 0.0 2.2 3 0 0 3 3 3 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_10 PF13460.1 ETO14091.1 - 0.034 14.1 0.1 0.28 11.1 0.0 2.0 2 0 0 2 2 2 0 NADH(P)-binding TrkA_N PF02254.13 ETO14091.1 - 0.087 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain WD40 PF00400.27 ETO14092.1 - 9.8e-78 253.5 19.2 3.3e-13 48.9 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO14092.1 - 2e-15 57.0 0.3 7.4e-08 32.3 0.0 3.1 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO14092.1 - 5.2e-08 31.4 4.8 0.038 12.1 0.9 4.5 1 1 3 4 4 4 3 Nucleoporin Nup120/160 PD40 PF07676.7 ETO14092.1 - 1.8e-06 27.4 14.0 5.2 6.8 0.1 7.0 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 ETO14092.1 - 3.3e-06 25.9 0.1 0.025 13.1 0.0 4.4 1 1 2 4 4 4 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region PQQ_2 PF13360.1 ETO14092.1 - 7.2e-06 25.6 0.7 0.00041 19.8 0.4 2.8 1 1 0 1 1 1 1 PQQ-like domain Nbas_N PF15492.1 ETO14092.1 - 9.9e-06 24.8 3.0 0.18 10.9 0.0 4.6 2 1 3 5 5 5 2 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 ETO14092.1 - 0.00023 19.5 3.9 0.4 8.9 0.3 3.3 1 1 0 2 2 2 2 Cytochrome D1 heme domain Str_synth PF03088.11 ETO14092.1 - 0.00045 20.1 0.8 3.6 7.6 0.0 5.0 4 3 3 7 7 6 1 Strictosidine synthase GSDH PF07995.6 ETO14092.1 - 0.0012 17.9 0.0 0.4 9.7 0.0 3.3 1 1 1 3 3 3 1 Glucose / Sorbosone dehydrogenase Me-amine-dh_H PF06433.6 ETO14092.1 - 0.021 13.4 0.0 1.3 7.6 0.0 2.9 3 0 0 3 3 3 0 Methylamine dehydrogenase heavy chain (MADH) DUF4473 PF14747.1 ETO14092.1 - 0.082 13.1 0.6 0.23 11.7 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) Proteasome_A_N PF10584.4 ETO14092.1 - 0.082 12.2 8.7 44 3.5 0.0 6.0 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 ETO14093.1 - 4.5e-73 238.7 16.2 2e-13 49.6 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO14093.1 - 3.6e-06 25.5 0.8 0.03 12.6 0.1 3.5 1 1 3 4 4 4 4 Cytochrome D1 heme domain Nup160 PF11715.3 ETO14093.1 - 1.3e-05 23.5 14.2 0.61 8.1 0.4 5.8 1 1 4 5 5 5 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO14093.1 - 0.00015 21.2 2.3 0.0063 15.9 1.2 3.3 1 1 0 1 1 1 1 PQQ-like domain PD40 PF07676.7 ETO14093.1 - 0.00072 19.1 3.0 0.81 9.4 0.0 4.3 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat PQQ PF01011.16 ETO14093.1 - 0.0042 16.5 0.7 2.1 8.0 0.0 4.1 5 0 0 5 5 5 1 PQQ enzyme repeat Nbas_N PF15492.1 ETO14093.1 - 0.0061 15.7 4.0 2.8 6.9 0.3 4.1 1 1 3 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Resistin PF06954.6 ETO14093.1 - 0.046 13.9 0.4 23 5.3 0.0 3.6 2 1 1 3 3 3 0 Resistin Guanylate_cyc PF00211.15 ETO14094.1 - 9.3e-11 41.4 0.0 1.8e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Lenti_VIF_2 PF07401.7 ETO14095.1 - 0.093 11.8 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Bovine Lentivirus VIF protein Dsh_C PF12316.3 ETO14095.1 - 2.2 8.3 11.2 4.1 7.4 7.7 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal EF-hand_7 PF13499.1 ETO14096.1 - 3.4e-05 23.8 1.0 0.21 11.7 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 ETO14096.1 - 0.00068 19.2 2.7 0.17 11.5 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain pair SSP160 PF06933.6 ETO14096.1 - 0.0015 16.5 0.7 0.0018 16.4 0.5 1.2 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 EF-hand_1 PF00036.27 ETO14096.1 - 0.0027 16.8 6.0 0.12 11.7 0.1 3.8 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 ETO14096.1 - 0.015 15.1 0.9 2.6 8.1 0.1 3.1 2 0 0 2 2 2 0 EF-hand domain NADH_dehy_S2_C PF06444.6 ETO14096.1 - 1.9 8.8 8.4 3.1 8.1 5.8 1.3 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 C-terminus RRM_1 PF00076.17 ETO14097.1 - 1.5e-06 27.7 0.1 8.3e-06 25.3 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO14097.1 - 0.0054 16.6 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO14097.1 - 0.021 14.6 0.1 0.069 13.0 0.1 1.9 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pex16 PF08610.5 ETO14098.1 - 1.1e-15 57.4 0.0 1e-13 51.0 0.0 2.0 1 1 0 1 1 1 1 Peroxisomal membrane protein (Pex16) DUF1741 PF08427.5 ETO14098.1 - 0.11 11.8 0.2 0.2 11.1 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1741) AAA_11 PF13086.1 ETO14099.1 - 7.5 6.0 21.2 0.37 10.3 2.6 2.4 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.20 ETO14100.1 - 2.9e-34 118.3 0.1 4.7e-34 117.7 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.24 ETO14100.1 - 1.1e-17 63.6 0.0 2e-13 49.9 0.0 2.7 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.12 ETO14100.1 - 1.5e-16 60.2 0.1 2.3e-16 59.6 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PhyH PF05721.8 ETO14101.1 - 6.7e-05 23.0 0.0 0.013 15.5 0.0 2.8 3 0 0 3 3 3 2 Phytanoyl-CoA dioxygenase (PhyH) Autotrns_rpt PF12951.2 ETO14101.1 - 0.21 11.3 2.0 0.41 10.3 1.4 1.4 1 0 0 1 1 1 0 Autotransporter-associated beta strand repeat Sugar_tr PF00083.19 ETO14102.1 - 1 7.8 2.8 2.2 6.7 1.9 1.5 1 0 0 1 1 1 0 Sugar (and other) transporter Mito_carr PF00153.22 ETO14103.1 - 5.5e-59 195.8 4.9 1.2e-19 69.7 0.0 4.2 4 0 0 4 4 4 4 Mitochondrial carrier protein Glyco_hydro_47 PF01532.15 ETO14104.1 - 4.4e-62 210.2 0.0 5.3e-62 209.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pkinase PF00069.20 ETO14105.1 - 2e-18 66.4 0.1 2.1e-17 63.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO14105.1 - 0.0024 16.9 0.0 0.0045 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 ETO14105.1 - 0.02 14.4 0.0 0.055 13.0 0.0 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase WD40 PF00400.27 ETO14106.1 - 9.7e-160 513.4 51.7 9.6e-12 44.3 0.3 15.4 15 0 0 15 15 15 15 WD domain, G-beta repeat NACHT PF05729.7 ETO14106.1 - 8.7e-09 35.2 0.0 1.8e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.7 ETO14106.1 - 0.002 17.7 25.3 9 6.0 0.0 9.9 11 0 0 11 11 11 2 WD40-like Beta Propeller Repeat AAA_22 PF13401.1 ETO14106.1 - 0.0047 17.0 0.0 0.016 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain Pentapeptide_4 PF13599.1 ETO14106.1 - 0.0057 16.4 0.4 0.0057 16.4 0.2 1.9 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) AAA_18 PF13238.1 ETO14106.1 - 0.011 16.0 0.3 0.069 13.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain Resistin PF06954.6 ETO14106.1 - 0.012 15.8 8.0 12 6.2 0.3 7.0 7 2 2 9 9 9 0 Resistin Pentapeptide PF00805.17 ETO14106.1 - 0.084 12.1 2.7 1.3 8.3 0.7 2.1 1 1 1 2 2 2 0 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 ETO14106.1 - 8 6.4 8.1 0.7 9.8 0.6 3.0 2 1 1 3 3 3 0 Pentapeptide repeats (9 copies) Peptidase_C1 PF00112.18 ETO14107.1 - 1.5e-37 129.5 0.5 2.7e-37 128.7 0.3 1.4 1 1 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 ETO14107.1 - 0.047 12.2 1.1 0.078 11.4 0.7 1.3 1 0 0 1 1 1 0 Peptidase C1-like family Ion_trans PF00520.26 ETO14109.1 - 0.032 13.4 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 Ion transport protein TPR_11 PF13414.1 ETO14110.1 - 6.1e-24 83.4 33.9 1.2e-08 34.5 0.3 5.8 2 2 6 8 8 8 8 TPR repeat TPR_1 PF00515.23 ETO14110.1 - 5.5e-20 70.0 23.3 0.0047 16.4 0.2 7.8 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETO14110.1 - 8.8e-15 53.3 27.9 0.045 13.6 0.0 8.5 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETO14110.1 - 1.2e-14 52.8 17.9 0.015 15.0 0.0 7.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 ETO14110.1 - 2e-13 50.4 12.4 1.7e-05 25.0 0.1 5.1 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO14110.1 - 2.4e-13 50.3 4.1 0.0037 17.8 0.0 5.3 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO14110.1 - 2.7e-13 49.2 4.6 0.078 13.6 0.1 7.1 4 3 3 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 ETO14110.1 - 4.4e-13 48.9 23.7 6.8e-06 25.9 0.7 5.5 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETO14110.1 - 3.3e-12 45.5 15.1 0.015 15.4 0.1 8.7 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETO14110.1 - 7.8e-09 35.2 3.3 0.029 14.2 0.0 4.6 4 1 0 4 4 4 2 Tetratricopeptide repeat SAM_2 PF07647.12 ETO14110.1 - 1e-07 31.6 0.1 2.4e-07 30.4 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) TPR_6 PF13174.1 ETO14110.1 - 3.4e-06 27.1 12.5 0.63 10.6 0.0 6.8 8 0 0 8 8 7 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO14110.1 - 6e-05 23.0 23.4 0.022 14.8 3.7 5.0 2 2 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 ETO14110.1 - 0.00038 19.6 0.1 0.26 10.5 0.0 3.1 2 0 0 2 2 2 1 SHNi-TPR Fis1_TPR_C PF14853.1 ETO14110.1 - 0.003 17.3 0.5 17 5.3 0.1 4.3 3 1 1 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.1 ETO14110.1 - 0.04 13.7 14.9 8.6 6.4 0.1 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.1 ETO14110.1 - 0.12 12.5 0.0 1.1 9.3 0.0 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 ETO14110.1 - 3.7 7.6 12.7 11 6.0 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF4176 PF13780.1 ETO14111.1 - 0.15 11.8 0.0 0.47 10.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4176) Pribosyltran PF00156.22 ETO14112.1 - 1.9e-18 66.3 0.0 2.9e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 ETO14112.1 - 0.0041 16.3 0.1 0.0065 15.6 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 ETO14112.1 - 0.036 13.3 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase 3Beta_HSD PF01073.14 ETO14114.1 - 7.9e-29 100.2 0.0 9.7e-29 99.9 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 ETO14114.1 - 1.2e-09 37.9 0.0 1.5e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ETO14114.1 - 0.034 13.0 0.0 0.044 12.6 0.0 1.1 1 0 0 1 1 1 0 Male sterility protein TGS PF02824.16 ETO14115.1 - 1.7e-21 75.7 0.1 3.6e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 ETO14115.1 - 2.6e-18 66.0 0.0 9.8e-18 64.1 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETO14115.1 - 1.5e-10 40.5 0.1 1.5e-09 37.3 0.0 2.3 3 0 0 3 3 3 1 Ferrous iron transport protein B Dynamin_N PF00350.18 ETO14115.1 - 0.0012 18.7 0.0 1.8 8.3 0.0 2.5 2 0 0 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 ETO14115.1 - 0.004 16.6 0.1 0.32 10.4 0.0 2.7 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 ETO14115.1 - 0.0042 15.9 0.0 0.0088 14.8 0.0 1.4 1 0 0 1 1 1 1 ArgK protein Miro PF08477.8 ETO14115.1 - 0.016 15.6 0.0 0.039 14.4 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 ETO14115.1 - 0.11 12.7 0.0 0.65 10.2 0.0 2.1 2 1 0 2 2 2 0 ABC transporter AAA_28 PF13521.1 ETO14115.1 - 0.14 12.1 0.2 1.3 8.9 0.1 2.5 3 0 0 3 3 3 0 AAA domain Thg1 PF04446.7 ETO14116.1 - 5.4e-29 100.5 0.1 5.1e-14 52.0 0.0 2.4 1 1 1 2 2 2 2 tRNAHis guanylyltransferase bZIP_1 PF00170.16 ETO14116.1 - 0.014 15.3 0.8 0.11 12.4 0.1 2.4 2 0 0 2 2 2 0 bZIP transcription factor Tropomyosin PF00261.15 ETO14116.1 - 0.045 12.8 0.1 0.1 11.6 0.1 1.6 1 0 0 1 1 1 0 Tropomyosin Vac_Fusion PF02346.11 ETO14116.1 - 0.057 12.8 0.4 0.45 9.9 0.0 2.6 2 0 0 2 2 2 0 Chordopoxvirus fusion protein Seryl_tRNA_N PF02403.17 ETO14116.1 - 0.4 10.7 4.0 0.58 10.1 0.1 2.8 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Pho88 PF10032.4 ETO14117.1 - 0.013 14.7 0.0 0.054 12.7 0.0 1.9 2 0 0 2 2 2 0 Phosphate transport (Pho88) NOA36 PF06524.7 ETO14118.1 - 0.95 8.6 20.2 1.8 7.7 14.0 1.5 1 0 0 1 1 1 0 NOA36 protein Gag_spuma PF03276.9 ETO14118.1 - 7.4 4.7 12.2 10 4.3 8.5 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Herpes_LMP1 PF05297.6 ETO14118.1 - 9 5.1 9.0 11 4.7 6.3 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) YoqO PF14037.1 ETO14120.1 - 0.25 11.4 2.0 0.27 11.3 1.4 1.3 1 1 0 1 1 1 0 YoqO-like protein LRR_6 PF13516.1 ETO14121.1 - 2.3e-08 33.2 23.8 0.22 11.7 0.1 6.4 6 0 0 6 6 6 5 Leucine Rich repeat Rav1p_C PF12234.3 ETO14122.1 - 5.7e-22 77.6 9.6 1.2e-21 76.6 6.7 1.5 1 0 0 1 1 1 1 RAVE protein 1 C terminal SR-25 PF10500.4 ETO14122.1 - 0.0043 16.5 8.4 0.0043 16.5 5.8 4.8 4 1 0 5 5 5 2 Nuclear RNA-splicing-associated protein SAM_1 PF00536.25 ETO14123.1 - 1.3e-07 31.6 0.2 3e-07 30.5 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO14123.1 - 3.4e-05 23.5 0.1 7.7e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 ETO14123.1 - 0.00078 19.1 0.0 0.0017 18.0 0.0 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Chordopox_G3 PF06129.7 ETO14126.1 - 0.074 13.2 0.4 0.074 13.2 0.3 2.5 2 0 0 2 2 2 0 Chordopoxvirus G3 protein BLVR PF06375.6 ETO14126.1 - 0.56 10.0 14.8 0.16 11.7 7.5 2.1 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) SGL PF08450.7 ETO14128.1 - 2.1e-06 27.3 0.1 0.01 15.2 0.0 3.1 1 1 1 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 ETO14128.1 - 1.4e-05 24.9 0.0 0.085 12.8 0.0 4.0 3 1 1 4 4 4 2 Arylesterase Lactonase PF10282.4 ETO14128.1 - 2.5e-05 23.5 0.9 0.00088 18.4 0.2 2.1 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller DEK_C PF08766.6 ETO14129.1 - 3.4e-13 49.1 0.5 5.2e-13 48.5 0.3 1.3 1 0 0 1 1 1 1 DEK C terminal domain PC4 PF02229.11 ETO14129.1 - 0.00027 20.0 0.0 0.0031 16.6 0.0 2.4 2 0 0 2 2 2 1 Transcriptional Coactivator p15 (PC4) EnY2 PF10163.4 ETO14129.1 - 0.037 13.9 1.8 0.087 12.7 0.9 1.9 1 1 1 2 2 2 0 Transcription factor e(y)2 Mem_trans PF03547.13 ETO14129.1 - 1.9 6.7 3.3 2.3 6.4 2.3 1.2 1 0 0 1 1 1 0 Membrane transport protein FLO_LFY PF01698.11 ETO14129.1 - 2.6 6.8 12.3 3.6 6.3 8.5 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Acetyltransf_13 PF13880.1 ETO14130.1 - 7.7e-26 89.6 0.1 1.3e-25 88.8 0.1 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_1 PF00583.19 ETO14130.1 - 0.0094 15.9 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family CENP-B_dimeris PF09026.5 ETO14130.1 - 0.03 14.5 0.2 12 6.2 0.2 2.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Acetyltransf_7 PF13508.1 ETO14130.1 - 0.03 14.4 0.0 0.13 12.4 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain TPR_12 PF13424.1 ETO14131.1 - 1.5e-28 98.5 7.1 8.4e-11 41.6 0.0 4.0 3 1 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO14131.1 - 2.7e-21 74.1 15.6 1.6e-06 27.4 0.2 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO14131.1 - 4.4e-18 64.6 6.6 1e-05 25.0 0.2 3.4 3 0 0 3 3 3 3 TPR repeat TPR_7 PF13176.1 ETO14131.1 - 1.2e-16 59.0 5.0 0.00013 21.5 0.1 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO14131.1 - 1.7e-15 55.5 14.7 1.3e-05 24.7 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO14131.1 - 2.9e-10 39.1 20.0 0.0098 15.6 0.1 5.0 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO14131.1 - 3.4e-08 33.1 0.0 0.3 11.0 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO14131.1 - 4.6e-06 26.4 3.1 0.83 10.0 0.0 5.0 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO14131.1 - 2.9e-05 24.2 4.5 0.081 13.4 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO14131.1 - 3.4e-05 23.9 9.2 0.024 14.7 0.5 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 ETO14131.1 - 0.0001 22.5 0.0 1.2 9.9 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO14131.1 - 0.00056 20.4 0.1 4.4 8.1 0.0 3.3 5 0 0 5 5 3 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO14131.1 - 0.0015 17.7 0.3 0.0066 15.6 0.0 2.3 3 0 0 3 3 3 1 SHNi-TPR Fis1_TPR_C PF14853.1 ETO14131.1 - 0.0062 16.3 3.4 0.26 11.2 0.2 2.7 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.1 ETO14131.1 - 0.0066 16.7 0.3 3.4 8.0 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat RadC PF04002.10 ETO14131.1 - 0.021 14.5 0.2 0.042 13.5 0.1 1.4 1 0 0 1 1 1 0 RadC-like JAB domain Clp_N PF02861.15 ETO14131.1 - 0.14 12.0 0.1 0.6 10.0 0.0 2.0 2 0 0 2 2 2 0 Clp amino terminal domain PPR PF01535.15 ETO14131.1 - 2.5 8.2 8.7 25 5.1 0.0 5.1 5 1 1 6 6 5 0 PPR repeat MIT PF04212.13 ETO14131.1 - 4.4 7.2 9.7 6.5 6.7 0.0 3.6 3 1 1 4 4 3 0 MIT (microtubule interacting and transport) domain VMA21 PF09446.5 ETO14132.1 - 0.024 14.5 1.9 0.053 13.4 1.3 1.6 1 0 0 1 1 1 0 VMA21-like domain zf-TRAF PF02176.13 ETO14133.1 - 3.8e-05 23.9 1.5 3.8e-05 23.9 1.1 2.8 3 0 0 3 3 3 1 TRAF-type zinc finger Tyr_Deacylase PF02580.11 ETO14134.1 - 1.2e-18 67.4 0.7 1.1e-17 64.3 0.2 2.2 2 1 0 2 2 2 1 D-Tyr-tRNA(Tyr) deacylase DUF4271 PF14093.1 ETO14134.1 - 0.11 12.1 4.1 0.13 11.9 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) adh_short PF00106.20 ETO14135.1 - 8.7e-17 61.5 0.1 1.7e-16 60.5 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETO14135.1 - 1.3e-09 37.9 0.0 2.1e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 ETO14135.1 - 5.5e-05 22.2 0.2 0.00017 20.5 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 ETO14135.1 - 0.029 14.1 0.2 0.067 12.9 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 ETO14135.1 - 0.11 11.8 0.0 0.26 10.6 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF601 PF04642.7 ETO14136.1 - 0.06 12.7 10.1 0.091 12.1 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF601 Pox_Ag35 PF03286.9 ETO14136.1 - 0.15 11.5 11.4 0.22 10.9 7.9 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DDHD PF02862.12 ETO14136.1 - 1.6 8.5 7.7 2.5 7.8 5.3 1.4 1 0 0 1 1 1 0 DDHD domain DUF1510 PF07423.6 ETO14136.1 - 4.9 6.4 18.5 7.7 5.8 12.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) ENTH PF01417.15 ETO14137.1 - 1.6e-09 37.6 0.9 2.1e-09 37.3 0.6 1.2 1 0 0 1 1 1 1 ENTH domain ArdA PF07275.6 ETO14137.1 - 0.05 13.8 0.6 0.079 13.2 0.4 1.3 1 0 0 1 1 1 0 Antirestriction protein (ArdA) DUF3944 PF13099.1 ETO14137.1 - 0.13 11.8 0.5 2.3 7.7 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3944) DUF1033 PF06279.6 ETO14137.1 - 0.27 11.0 2.4 0.83 9.4 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1033) ASC PF00858.19 ETO14138.1 - 0.024 13.3 0.6 0.036 12.7 0.4 1.2 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel DUF809 PF05663.6 ETO14139.1 - 0.0057 16.5 0.6 0.11 12.4 0.7 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF809) Radical_SAM PF04055.16 ETO14139.1 - 0.054 13.6 0.0 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 Radical SAM superfamily DEAD PF00270.24 ETO14141.1 - 1.5e-21 76.6 0.0 5e-21 74.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETO14141.1 - 4.4e-07 29.6 0.1 9.9e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Atrophin-1 PF03154.10 ETO14141.1 - 0.058 11.5 3.8 0.086 10.9 2.6 1.2 1 0 0 1 1 1 0 Atrophin-1 family V_ATPase_I PF01496.14 ETO14141.1 - 0.35 8.6 5.2 0.54 8.0 2.8 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF1180 PF06679.7 ETO14142.1 - 0.0066 16.3 7.6 0.068 13.0 0.6 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1180) Mito_fiss_reg PF05308.6 ETO14142.1 - 2.4 7.4 10.0 0.7 9.2 0.8 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator Sulfatase PF00884.18 ETO14145.1 - 1.7e-33 116.1 2.9 2.1e-33 115.8 2.0 1.0 1 0 0 1 1 1 1 Sulfatase LUC7 PF03194.10 ETO14145.1 - 0.18 11.3 0.0 0.26 10.7 0.0 1.1 1 0 0 1 1 1 0 LUC7 N_terminus WD40 PF00400.27 ETO14146.1 - 1.7e-71 233.7 20.8 1.7e-11 43.4 0.4 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO14146.1 - 1.2e-15 56.7 5.0 0.0033 15.6 0.0 5.7 2 2 2 5 5 5 5 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO14146.1 - 0.0036 17.1 0.1 1.1 9.2 0.0 4.0 4 1 1 5 5 5 1 Domain of unknown function (DUF3601) HAD PF12710.2 ETO14146.1 - 0.2 11.8 1.9 16 5.5 0.0 3.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase AHS1 PF02682.11 ETO14147.1 - 0.046 13.1 0.1 0.093 12.1 0.1 1.4 1 0 0 1 1 1 0 Allophanate hydrolase subunit 1 SlyX PF04102.7 ETO14147.1 - 0.43 10.9 4.3 0.34 11.2 1.0 2.4 2 0 0 2 2 2 0 SlyX RPM2 PF08579.6 ETO14147.1 - 0.44 10.6 8.9 0.033 14.3 2.2 2.0 2 1 0 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) Cys_knot PF00007.17 ETO14147.1 - 1.4 9.0 12.6 0.28 11.2 4.8 2.2 1 1 0 2 2 2 0 Cystine-knot domain EF-hand_1 PF00036.27 ETO14148.1 - 0.0005 19.1 0.0 0.001 18.1 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 ETO14148.1 - 0.017 14.9 0.1 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain Cullin_binding PF03556.10 ETO14151.1 - 1.7e-21 76.5 5.9 1.7e-21 76.5 4.1 2.0 2 0 0 2 2 2 1 Cullin binding UBA_4 PF14555.1 ETO14151.1 - 1.3e-10 40.6 0.1 2.4e-10 39.7 0.1 1.4 1 0 0 1 1 1 1 UBA-like domain CRAL_TRIO_N PF03765.10 ETO14151.1 - 0.0089 16.1 0.4 0.053 13.6 0.0 2.5 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain AATase PF07247.7 ETO14152.1 - 0.0075 14.8 0.0 0.01 14.3 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase FIVAR PF07554.8 ETO14152.1 - 0.014 15.6 0.4 0.028 14.6 0.2 1.5 1 0 0 1 1 1 0 Uncharacterised Sugar-binding Domain YusW PF14039.1 ETO14152.1 - 0.07 13.4 1.7 0.64 10.3 0.2 2.1 2 0 0 2 2 2 0 YusW-like protein SapC PF07277.6 ETO14153.1 - 0.051 12.8 0.5 0.086 12.1 0.4 1.3 1 0 0 1 1 1 0 SapC Helicase_C PF00271.26 ETO14154.1 - 2.2e-27 94.7 0.3 4.9e-27 93.5 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Fanconi_A PF03511.9 ETO14154.1 - 0.014 15.1 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 Fanconi anaemia group A protein DUF2529 PF10740.4 ETO14154.1 - 0.071 12.5 0.1 8.6 5.7 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2529) Sec3_C PF09763.4 ETO14155.1 - 2.4 6.2 5.6 3.1 5.8 3.9 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 DUF515 PF04415.7 ETO14155.1 - 5 5.2 10.0 6.5 4.8 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SPRY PF00622.23 ETO14156.1 - 5.9e-07 29.6 1.0 7.3e-07 29.3 0.1 1.6 2 0 0 2 2 2 1 SPRY domain DUF2721 PF11026.3 ETO14157.1 - 0.015 14.9 3.6 1.9 8.1 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) SdpI PF13630.1 ETO14157.1 - 0.089 12.5 3.1 4.2 7.1 0.3 2.9 2 1 1 3 3 3 0 SdpI/YhfL protein family DUF202 PF02656.10 ETO14157.1 - 0.24 11.6 4.9 0.57 10.4 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF202) TauE PF01925.14 ETO14157.1 - 0.59 9.5 7.0 0.22 10.9 1.2 2.0 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE Secretin_N_2 PF07655.8 ETO14157.1 - 2 8.8 20.7 0.93 9.9 8.1 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain WD40 PF00400.27 ETO14158.1 - 1e-55 183.7 24.1 7.9e-12 44.5 0.5 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO14158.1 - 1.7e-11 42.9 7.8 0.0058 14.8 0.1 5.2 2 1 2 5 5 5 5 Nucleoporin Nup120/160 HAD PF12710.2 ETO14158.1 - 0.015 15.4 0.8 0.64 10.1 0.6 2.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase WD40 PF00400.27 ETO14159.1 - 1.4e-62 205.4 27.4 4.5e-11 42.1 0.5 8.7 9 0 0 9 9 9 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO14159.1 - 1.7e-09 36.4 10.9 0.22 9.5 0.0 5.5 2 2 0 5 5 5 5 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO14159.1 - 3.5e-06 27.3 2.3 3.5e-06 27.3 1.6 2.7 3 0 0 3 3 3 1 TRAF-type zinc finger TMCO5 PF14992.1 ETO14159.1 - 0.0044 16.2 13.0 0.0074 15.4 9.0 1.3 1 0 0 1 1 1 1 TMCO5 family NAD_binding_5 PF07994.7 ETO14159.1 - 1.2 8.5 4.0 2.2 7.6 2.7 1.3 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase IncA PF04156.9 ETO14159.1 - 2.3 7.7 15.7 4.3 6.8 10.9 1.4 1 0 0 1 1 1 0 IncA protein DUF1068 PF06364.7 ETO14159.1 - 2.7 7.5 8.2 5.3 6.6 5.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) DUF1943 PF09172.6 ETO14160.1 - 1.3e-05 24.2 2.8 4.1e-05 22.5 1.9 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1943) DUF481 PF04338.7 ETO14160.1 - 0.018 14.7 0.0 0.039 13.6 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF481 SprA_N PF14349.1 ETO14160.1 - 0.018 14.2 0.5 0.024 13.8 0.3 1.2 1 0 0 1 1 1 0 Motility related/secretion protein LEA_2 PF03168.8 ETO14160.1 - 0.036 14.4 6.8 6.4 7.2 4.7 3.0 1 1 1 2 2 2 0 Late embryogenesis abundant protein Spo0M PF07070.6 ETO14160.1 - 0.093 12.0 7.3 0.15 11.3 5.0 1.4 1 1 0 1 1 1 0 SpoOM protein E1_DerP2_DerF2 PF02221.10 ETO14160.1 - 0.26 11.5 6.4 1.1 9.4 2.2 2.4 1 1 1 2 2 2 0 ML domain DUF1062 PF06353.7 ETO14160.1 - 0.76 9.9 10.3 1.2 9.3 1.7 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1062) AMP-binding_C_2 PF14535.1 ETO14160.1 - 1.1 9.3 12.9 7.1 6.7 8.8 2.4 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain Spore_YunB PF09560.5 ETO14160.1 - 5.6 6.7 11.3 14 5.5 3.6 2.7 1 1 1 2 2 2 0 Sporulation protein YunB (Spo_YunB) Glyco_hydro_2 PF00703.16 ETO14160.1 - 8 6.9 7.5 15 6.0 3.9 2.3 1 1 1 2 2 2 0 Glycosyl hydrolases family 2 GTP_EFTU PF00009.22 ETO14164.1 - 1.3e-09 37.7 0.0 6.9e-06 25.6 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 ETO14164.1 - 1.3e-09 38.0 0.1 3.6e-09 36.6 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 ETO14164.1 - 0.0023 17.7 0.7 0.018 14.8 0.1 2.3 1 1 1 2 2 2 1 Dynamin family DUF258 PF03193.11 ETO14164.1 - 0.0026 16.9 0.0 0.0051 16.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 ETO14164.1 - 0.0036 16.8 0.0 2 7.8 0.0 2.5 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein Avirulence PF03377.8 ETO14164.1 - 0.0039 15.9 0.0 0.0061 15.3 0.0 1.2 1 0 0 1 1 1 1 Xanthomonas avirulence protein, Avr/PthA Miro PF08477.8 ETO14164.1 - 0.0055 17.2 0.2 0.17 12.4 0.0 2.9 2 1 1 3 3 3 1 Miro-like protein Arf PF00025.16 ETO14164.1 - 0.0062 15.8 0.1 0.37 10.0 0.0 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family FeoB_N PF02421.13 ETO14164.1 - 0.0077 15.5 0.2 0.35 10.1 0.0 2.6 2 0 0 2 2 2 1 Ferrous iron transport protein B Ras PF00071.17 ETO14164.1 - 0.01 15.2 0.0 2.4 7.5 0.0 2.5 2 0 0 2 2 2 0 Ras family SRPRB PF09439.5 ETO14164.1 - 0.093 11.9 1.3 4.1 6.5 0.2 2.5 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit ALIX_LYPXL_bnd PF13949.1 ETO14165.1 - 4.3e-40 137.5 16.0 5.1e-40 137.2 11.1 1.0 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV GlnE PF03710.10 ETO14165.1 - 0.0034 16.6 1.8 0.0069 15.6 1.3 1.5 1 0 0 1 1 1 1 Glutamate-ammonia ligase adenylyltransferase Snapin_Pallidin PF14712.1 ETO14165.1 - 0.0068 16.6 2.4 0.0068 16.6 1.7 3.5 2 2 1 3 3 3 1 Snapin/Pallidin DUF3510 PF12022.3 ETO14165.1 - 0.11 12.6 0.4 0.11 12.6 0.2 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF3510) PXA PF02194.10 ETO14165.1 - 0.14 11.6 4.6 0.49 9.9 0.7 2.2 2 0 0 2 2 2 0 PXA domain SieB PF14163.1 ETO14165.1 - 0.18 11.4 2.1 0.27 10.7 0.2 2.1 2 0 0 2 2 2 0 Superinfection exclusion protein B Laminin_II PF06009.7 ETO14165.1 - 0.18 11.5 11.1 0.51 10.1 3.3 2.5 2 0 0 2 2 2 0 Laminin Domain II DUF2385 PF09539.5 ETO14165.1 - 0.24 11.8 2.0 4.1 7.8 0.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2385) Ax_dynein_light PF10211.4 ETO14165.1 - 0.32 10.8 15.1 0.67 9.7 0.7 2.4 2 0 0 2 2 2 0 Axonemal dynein light chain DUF3829 PF12889.2 ETO14165.1 - 0.35 10.0 13.7 0.87 8.7 7.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3829) Uds1 PF15456.1 ETO14165.1 - 0.5 10.3 10.4 6 6.8 3.4 2.6 1 1 1 2 2 2 0 Up-regulated During Septation DUF3585 PF12130.3 ETO14165.1 - 0.57 10.0 11.7 0.49 10.2 5.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3585) DUF4279 PF14106.1 ETO14165.1 - 0.58 10.0 4.6 0.36 10.7 0.8 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4279) DUF342 PF03961.8 ETO14165.1 - 0.77 8.0 18.2 1 7.6 4.7 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF342) Syntaxin_2 PF14523.1 ETO14165.1 - 0.83 9.7 20.4 21 5.2 8.4 2.9 1 1 1 2 2 2 0 Syntaxin-like protein Mnd1 PF03962.10 ETO14165.1 - 0.92 9.1 18.4 0.28 10.8 0.2 2.8 2 1 1 3 3 3 0 Mnd1 family DUF904 PF06005.7 ETO14165.1 - 1.1 9.5 16.6 1.2 9.4 2.8 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF904) Cytochrom_B562 PF07361.6 ETO14165.1 - 1.4 9.4 11.8 6.1 7.3 2.7 2.8 2 2 1 3 3 3 0 Cytochrome b562 FCH PF00611.18 ETO14165.1 - 1.4 9.1 10.6 7.7 6.7 2.0 3.8 2 1 0 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain zf-C4H2 PF10146.4 ETO14165.1 - 1.4 8.8 14.1 0.23 11.4 4.3 2.3 1 1 1 2 2 2 0 Zinc finger-containing protein DUF4239 PF14023.1 ETO14165.1 - 3.1 7.0 6.3 33 3.7 0.0 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF4239) IncA PF04156.9 ETO14165.1 - 5.1 6.6 20.1 0.6 9.6 0.2 2.6 2 1 0 2 2 2 0 IncA protein Cob_adeno_trans PF01923.13 ETO14165.1 - 6.1 6.6 7.3 8.5 6.1 0.5 2.3 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Apolipoprotein PF01442.13 ETO14166.1 - 0.0042 16.6 0.1 0.0049 16.4 0.0 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain RRM_6 PF14259.1 ETO14167.1 - 3.1e-24 84.7 2.2 3.4e-08 33.3 0.1 5.3 5 1 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO14167.1 - 7.2e-23 80.0 1.1 2.3e-06 27.1 0.3 6.3 6 1 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO14167.1 - 4.8e-14 51.9 2.2 9.1e-05 22.2 0.1 3.8 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ICAT PF06384.6 ETO14168.1 - 2.7e-11 43.0 0.7 5.7e-11 42.0 0.5 1.5 1 0 0 1 1 1 1 Beta-catenin-interacting protein ICAT GvpG PF05120.7 ETO14168.1 - 0.002 17.8 1.4 0.002 17.8 1.0 2.4 2 1 0 2 2 2 1 Gas vesicle protein G ApoLp-III PF07464.6 ETO14168.1 - 0.016 15.2 1.8 0.016 15.2 1.3 2.6 1 1 2 3 3 3 0 Apolipophorin-III precursor (apoLp-III) DUF1336 PF07059.7 ETO14168.1 - 0.017 14.5 0.2 0.029 13.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1336) Med10 PF09748.4 ETO14168.1 - 0.39 10.5 9.7 1e+03 -0.6 6.7 3.3 1 1 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex DUF3452 PF11934.3 ETO14168.1 - 0.72 9.1 5.4 2.8 7.2 3.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) Erythro_esteras PF05139.9 ETO14168.1 - 0.95 8.5 4.4 0.55 9.3 0.7 1.9 1 1 1 2 2 2 0 Erythromycin esterase PG_binding_1 PF01471.13 ETO14168.1 - 0.95 9.4 4.9 1.3 9.0 0.6 2.5 2 1 0 2 2 2 0 Putative peptidoglycan binding domain RPA_interact_M PF14767.1 ETO14168.1 - 2.4 8.9 12.5 0.17 12.6 1.0 2.4 2 0 0 2 2 2 0 Replication protein A interacting middle MCM_N PF14551.1 ETO14168.1 - 5.2 7.5 6.9 16 6.0 4.7 2.0 1 1 0 1 1 1 0 MCM N-terminal domain YtxH PF12732.2 ETO14168.1 - 8 6.9 12.6 0.62 10.4 1.1 2.5 2 1 0 2 2 2 0 YtxH-like protein DMAP_binding PF06464.6 ETO14168.1 - 9.1 6.9 9.4 0.41 11.2 2.2 2.2 2 2 0 2 2 2 0 DMAP1-binding Domain SHR3_chaperone PF08229.6 ETO14169.1 - 0.51 9.2 0.0 0.51 9.2 0.0 2.9 4 0 0 4 4 4 0 ER membrane protein SH3 DUF1501 PF07394.7 ETO14170.1 - 1 8.1 5.5 0.082 11.7 0.6 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1501) Zip PF02535.17 ETO14170.1 - 9.5 5.1 9.7 10 5.0 6.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter IFRD PF05004.8 ETO14171.1 - 0.093 11.8 4.3 0.15 11.1 3.0 1.3 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) Fzo_mitofusin PF04799.8 ETO14171.1 - 0.71 9.2 3.5 0.96 8.8 2.4 1.2 1 0 0 1 1 1 0 fzo-like conserved region APG6 PF04111.7 ETO14171.1 - 0.74 8.8 8.6 1 8.3 5.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 ETO14171.1 - 1 8.2 7.2 1.5 7.6 5.0 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 ETO14171.1 - 2.1 7.9 12.9 2.6 7.5 8.9 1.3 1 1 0 1 1 1 0 IncA protein TMEM247 PF15444.1 ETO14171.1 - 2.7 7.7 13.4 3.6 7.3 8.3 1.8 1 1 1 2 2 2 0 Transmembrane protein 247 SR-25 PF10500.4 ETO14171.1 - 8.9 5.7 41.3 18 4.7 28.6 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein SNF2_N PF00176.18 ETO14172.1 - 3e-54 183.8 0.0 3.8e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 ETO14172.1 - 4e-06 26.4 0.0 8.8e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 ETO14172.1 - 1.8e-05 24.6 0.1 0.00021 21.1 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 ETO14172.1 - 0.002 18.2 0.1 0.017 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 ETO14172.1 - 0.027 13.4 0.0 0.064 12.2 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 ETO14173.1 - 4.5e-18 65.7 0.4 9.9e-18 64.6 0.0 1.8 2 1 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) PELOTA_1 PF15608.1 ETO14173.1 - 0.1 12.3 1.4 0.13 12.0 0.1 1.8 2 0 0 2 2 2 0 PELOTA RNA binding domain AAA PF00004.24 ETO14174.1 - 0.01 16.0 4.6 0.027 14.6 0.2 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 ETO14174.1 - 0.012 14.8 0.7 0.027 13.6 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 ETO14174.1 - 0.066 12.9 0.1 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain DUF1675 PF07897.6 ETO14174.1 - 0.68 9.7 16.9 1.2 8.9 11.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Helicase_C PF00271.26 ETO14175.1 - 3e-14 52.6 0.3 6.8e-11 41.8 0.1 3.2 2 1 0 2 2 2 2 Helicase conserved C-terminal domain Utp11 PF03998.8 ETO14176.1 - 0.008 16.0 13.3 0.0089 15.8 9.2 1.1 1 0 0 1 1 1 1 Utp11 protein GIIM PF08388.6 ETO14176.1 - 0.16 11.7 0.5 0.16 11.7 0.3 2.8 2 1 1 3 3 3 0 Group II intron, maturase-specific domain FAA_hydrolase_N PF09298.6 ETO14176.1 - 0.2 11.6 1.7 0.28 11.1 1.2 1.3 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal Atg14 PF10186.4 ETO14176.1 - 0.74 8.6 10.8 0.82 8.5 7.5 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 ETO14176.1 - 1.2 8.0 12.5 1.5 7.7 8.7 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 CM_2 PF01817.16 ETO14176.1 - 1.4 9.0 10.9 0.69 10.0 3.4 2.2 1 1 1 2 2 2 0 Chorismate mutase type II CENP-H PF05837.7 ETO14176.1 - 2.3 8.4 17.3 4.3 7.5 12.0 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Bud13 PF09736.4 ETO14176.1 - 5.2 7.3 15.5 6.8 6.9 10.7 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Gly_transf_sug PF04488.10 ETO14178.1 - 1.6e-09 38.0 0.3 4e-09 36.7 0.2 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 ETO14178.1 - 9.9e-05 21.6 0.1 0.00019 20.7 0.0 1.4 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein SNF2_N PF00176.18 ETO14179.1 - 0.0064 15.3 0.2 0.0064 15.3 0.1 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromo_TP PF07524.8 ETO14179.1 - 0.035 13.8 0.0 0.086 12.5 0.0 1.7 1 0 0 1 1 1 0 Bromodomain associated CTDII PF01556.13 ETO14180.1 - 1.6e-17 63.1 0.2 3.4e-15 55.6 0.0 2.3 2 0 0 2 2 2 2 DnaJ C terminal domain DUF2379 PF09543.5 ETO14181.1 - 0.043 13.7 3.2 2.2 8.2 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2379) PMSI1 PF15322.1 ETO14181.1 - 0.078 12.0 3.1 0.096 11.7 2.2 1.0 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative RNA_lig_T4_1 PF09511.5 ETO14181.1 - 0.94 8.9 6.7 1.5 8.2 4.6 1.4 1 1 0 1 1 1 0 RNA ligase G-alpha PF00503.15 ETO14184.1 - 3.3e-40 137.9 36.1 2.4e-38 131.8 24.7 3.7 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO14184.1 - 5.7e-07 28.9 2.2 5.3e-05 22.5 0.0 2.8 2 0 0 2 2 2 2 ADP-ribosylation factor family DUF3037 PF11236.3 ETO14184.1 - 7.6 6.6 9.5 15 5.6 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3037) Ribosomal_60s PF00428.14 ETO14185.1 - 4.1e-14 52.7 2.0 6e-14 52.2 1.4 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Nop53 PF07767.6 ETO14187.1 - 4.8 6.0 16.7 0.29 10.0 7.0 1.8 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Ank PF00023.25 ETO14188.1 - 3.7e-22 76.9 0.0 6.2e-10 38.3 0.0 5.0 4 1 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 ETO14188.1 - 1.3e-18 66.9 2.4 3.8e-09 36.8 0.1 3.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO14188.1 - 3.3e-18 65.8 2.7 3e-16 59.5 0.5 3.5 3 2 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO14188.1 - 1.6e-17 63.1 0.5 1.4e-07 31.4 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO14188.1 - 1.9e-15 55.4 0.1 3.1e-06 26.8 0.0 5.1 5 0 0 5 5 5 2 Ankyrin repeat SAM_1 PF00536.25 ETO14188.1 - 4.6e-13 49.1 0.2 2e-12 47.0 0.1 2.0 1 1 1 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO14188.1 - 1e-12 47.7 0.1 1.8e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF3342 PF11822.3 ETO14190.1 - 9.1e-53 179.4 16.3 1.1e-52 179.1 11.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) BTB PF00651.26 ETO14190.1 - 1.8e-05 24.6 0.4 4e-05 23.5 0.3 1.6 1 0 0 1 1 1 1 BTB/POZ domain Phage_FRD3 PF05798.6 ETO14190.1 - 0.032 14.5 0.2 0.065 13.5 0.1 1.5 1 0 0 1 1 1 0 Bacteriophage FRD3 protein zf-Dof PF02701.10 ETO14190.1 - 0.1 12.5 0.2 0.1 12.5 0.1 2.5 3 0 0 3 3 3 0 Dof domain, zinc finger DUF1803 PF08820.5 ETO14190.1 - 0.5 10.0 5.1 0.26 11.0 0.7 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1803) Ras PF00071.17 ETO14191.1 - 2.6e-32 111.4 0.1 4.1e-32 110.8 0.1 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO14191.1 - 2.3e-07 31.3 0.0 4.6e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO14191.1 - 0.00012 21.3 0.2 0.00025 20.3 0.1 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family UMP1 PF05348.6 ETO14191.1 - 0.00015 21.7 0.1 0.00027 20.9 0.1 1.3 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Cytochrom_B_N_2 PF13631.1 ETO14191.1 - 0.017 14.9 0.1 0.06 13.1 0.1 1.9 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB FeoB_N PF02421.13 ETO14191.1 - 0.027 13.7 0.1 0.045 13.0 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B Pox_A9 PF04835.7 ETO14191.1 - 0.031 14.1 3.7 4.7 7.1 0.1 2.7 2 0 0 2 2 2 0 A9 protein conserved region HemX PF04375.9 ETO14192.1 - 0.012 14.2 0.4 0.023 13.3 0.1 1.5 1 1 0 1 1 1 0 HemX HALZ PF02183.13 ETO14192.1 - 0.24 11.1 6.7 0.085 12.5 0.9 2.7 2 1 1 3 3 3 0 Homeobox associated leucine zipper DUF3373 PF11853.3 ETO14192.1 - 0.51 8.8 3.3 0.88 8.0 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Fib_alpha PF08702.5 ETO14192.1 - 0.66 10.0 11.0 1.4 9.0 7.6 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Pox_A_type_inc PF04508.7 ETO14192.1 - 3.1 7.8 8.0 35 4.5 0.1 4.2 3 1 0 3 3 3 0 Viral A-type inclusion protein repeat DUF3450 PF11932.3 ETO14192.1 - 4.9 6.3 10.5 1.2 8.3 5.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) EF-hand_7 PF13499.1 ETO14193.1 - 1.5e-13 50.6 9.0 2.2e-08 34.1 1.8 2.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 ETO14193.1 - 2.3e-10 39.8 11.2 2.7e-06 26.8 1.2 3.5 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 ETO14193.1 - 8.5e-10 37.2 12.4 0.0017 17.4 0.4 4.9 5 1 1 6 6 6 3 EF hand EF-hand_6 PF13405.1 ETO14193.1 - 1.4e-07 30.7 8.8 0.0012 18.5 0.8 4.8 3 1 1 4 4 4 2 EF-hand domain EF-hand_4 PF12763.2 ETO14193.1 - 0.00015 21.4 3.6 0.0042 16.8 0.5 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand TerB PF05099.8 ETO14193.1 - 0.0034 17.1 2.9 0.92 9.2 0.3 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB EF-hand_5 PF13202.1 ETO14193.1 - 0.0051 16.0 13.2 0.12 11.8 0.0 4.9 6 0 0 6 6 6 1 EF hand SPARC_Ca_bdg PF10591.4 ETO14193.1 - 0.01 15.8 0.9 0.032 14.2 0.2 1.9 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Peptidase_S46 PF10459.4 ETO14193.1 - 0.038 12.4 0.5 0.038 12.4 0.4 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF592 PF04574.8 ETO14193.1 - 0.073 12.6 1.1 0.13 11.7 0.4 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF592) EF-hand_like PF09279.6 ETO14193.1 - 0.23 11.4 1.9 0.43 10.6 0.5 2.1 1 1 1 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like RRM_6 PF14259.1 ETO14194.1 - 0.0023 17.8 0.0 0.041 13.8 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO14194.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tnp_zf-ribbon_2 PF13842.1 ETO14195.1 - 0.35 11.3 3.9 0.91 9.9 2.7 1.7 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon FBPase PF00316.15 ETO14196.1 - 1.6e-67 227.6 0.0 2.7e-66 223.6 0.0 1.9 1 1 0 1 1 1 1 Fructose-1-6-bisphosphatase YyzF PF14116.1 ETO14196.1 - 0.048 13.6 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 YyzF-like protein Herpes_UL14 PF03580.9 ETO14197.1 - 0.00035 20.4 1.2 0.00045 20.0 0.8 1.3 1 0 0 1 1 1 1 Herpesvirus UL14-like protein DUF968 PF06147.6 ETO14197.1 - 0.35 10.7 5.1 0.61 9.9 2.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF968) Bud13 PF09736.4 ETO14197.1 - 0.75 10.0 5.8 0.92 9.7 4.0 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex COG4 PF08318.7 ETO14198.1 - 4.1e-24 84.9 10.9 4.1e-24 84.9 7.6 2.2 3 0 0 3 3 3 1 COG4 transport protein DIL PF01843.14 ETO14198.1 - 6.6e-05 22.7 2.5 0.00033 20.4 0.3 2.9 1 1 1 2 2 2 1 DIL domain MerR_2 PF13591.1 ETO14198.1 - 0.26 10.9 2.4 0.23 11.1 0.2 2.1 2 0 0 2 2 2 0 MerR HTH family regulatory protein ING PF12998.2 ETO14198.1 - 0.4 10.9 6.2 0.14 12.4 0.3 3.2 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Carb_kinase PF01256.12 ETO14199.1 - 4e-21 75.4 0.0 1.8e-09 37.2 0.0 3.2 2 1 0 2 2 2 2 Carbohydrate kinase PmrD PF11183.3 ETO14199.1 - 0.0057 16.4 0.1 1.2 8.9 0.0 2.7 2 0 0 2 2 2 2 Polymyxin resistance protein PmrD HK PF02110.10 ETO14199.1 - 0.14 11.3 0.1 0.4 9.8 0.0 1.8 3 0 0 3 3 3 0 Hydroxyethylthiazole kinase family FLO_LFY PF01698.11 ETO14201.1 - 1.9 7.2 9.5 2.3 6.9 6.6 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Ion_trans PF00520.26 ETO14202.1 - 1.1e-09 37.8 14.3 3.2e-09 36.3 9.9 1.8 1 0 0 1 1 1 1 Ion transport protein G-alpha PF00503.15 ETO14203.1 - 1.5e-57 195.0 1.9 1.8e-57 194.8 1.3 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO14203.1 - 7.6e-13 48.0 0.3 1.2e-12 47.4 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 ETO14203.1 - 8.5e-05 23.0 0.1 0.00018 22.0 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 ETO14203.1 - 0.006 15.7 0.1 0.0098 15.0 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF996 PF06195.8 ETO14204.1 - 0.1 12.6 4.6 0.62 10.0 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF996) cNMP_binding PF00027.24 ETO14205.1 - 2.7e-38 129.6 0.2 8.6e-20 70.3 0.0 2.8 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain LrgB PF04172.11 ETO14205.1 - 0.049 12.7 0.7 0.098 11.7 0.5 1.4 1 0 0 1 1 1 0 LrgB-like family rve_2 PF13333.1 ETO14206.1 - 0.029 14.4 0.2 0.11 12.5 0.1 2.1 1 1 0 1 1 1 0 Integrase core domain DUF1767 PF08585.7 ETO14207.1 - 6.9e-12 45.4 0.0 1.1e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Rad60-SLD PF11976.3 ETO14207.1 - 0.081 12.6 0.9 0.16 11.7 0.6 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like zf-DHHC PF01529.15 ETO14208.1 - 3.9e-29 101.2 16.2 3.9e-29 101.2 11.2 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase Mem_trans PF03547.13 ETO14208.1 - 0.07 11.4 0.0 0.074 11.3 0.0 1.2 1 0 0 1 1 1 0 Membrane transport protein DUF1272 PF06906.6 ETO14208.1 - 1.1 9.1 10.8 4 7.3 4.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Pex14_N PF04695.8 ETO14208.1 - 3.5 7.6 7.2 5.4 7.0 5.0 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SCAMP PF04144.8 ETO14209.1 - 2.7e-07 30.6 0.1 3.4e-07 30.3 0.1 1.1 1 0 0 1 1 1 1 SCAMP family Kinesin PF00225.18 ETO14211.1 - 1.1e-68 231.4 0.2 1.1e-68 231.4 0.2 1.7 2 0 0 2 2 2 1 Kinesin motor domain Laminin_II PF06009.7 ETO14211.1 - 0.0016 18.1 6.7 0.02 14.6 0.1 2.9 3 0 0 3 3 3 1 Laminin Domain II PspA_IM30 PF04012.7 ETO14211.1 - 0.0084 15.4 4.2 0.0084 15.4 2.9 2.8 2 1 0 2 2 2 1 PspA/IM30 family SlyX PF04102.7 ETO14211.1 - 0.012 15.9 5.0 0.3 11.4 1.2 3.5 2 1 0 2 2 2 0 SlyX bZIP_2 PF07716.10 ETO14211.1 - 0.017 14.8 1.6 0.017 14.8 1.1 2.8 4 0 0 4 4 2 0 Basic region leucine zipper IncA PF04156.9 ETO14211.1 - 0.02 14.5 14.3 0.24 10.9 5.1 2.4 1 1 0 2 2 2 0 IncA protein Uds1 PF15456.1 ETO14211.1 - 0.035 14.1 12.5 17 5.4 8.7 2.5 1 1 0 1 1 1 0 Up-regulated During Septation FliD_N PF02465.13 ETO14211.1 - 0.035 14.4 6.8 0.18 12.1 0.4 3.5 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF948 PF06103.6 ETO14211.1 - 0.057 13.2 6.4 0.065 13.1 0.6 2.7 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF948) ADIP PF11559.3 ETO14211.1 - 0.1 12.5 12.2 0.68 9.8 2.4 3.0 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.6 ETO14211.1 - 0.14 12.0 1.5 0.69 9.8 0.1 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Tropomyosin PF00261.15 ETO14211.1 - 0.5 9.4 20.4 22 4.0 9.7 2.6 1 1 1 2 2 2 0 Tropomyosin HR1 PF02185.11 ETO14211.1 - 0.51 10.1 11.0 0.22 11.2 1.2 3.4 3 1 1 4 4 4 0 Hr1 repeat DUF4201 PF13870.1 ETO14211.1 - 0.79 9.1 11.3 2.9 7.2 2.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Seryl_tRNA_N PF02403.17 ETO14211.1 - 0.86 9.6 20.4 1.3 9.1 1.6 3.4 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.7 ETO14211.1 - 1.3 9.2 5.3 4.8 7.5 0.4 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Prefoldin PF02996.12 ETO14211.1 - 1.8 8.2 13.6 2.9 7.5 2.2 3.2 3 0 0 3 3 3 0 Prefoldin subunit Fib_alpha PF08702.5 ETO14211.1 - 2 8.5 13.6 5.5 7.1 0.8 2.9 3 1 0 4 4 2 0 Fibrinogen alpha/beta chain family DUF3573 PF12097.3 ETO14211.1 - 2.7 6.4 6.9 2.7 6.5 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) Striatin PF08232.7 ETO14211.1 - 3.2 8.0 15.4 0.88 9.8 2.9 2.9 1 1 2 3 3 3 0 Striatin family BLOC1_2 PF10046.4 ETO14211.1 - 4.1 7.6 9.9 1.2 9.2 0.5 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 V-SNARE PF05008.10 ETO14211.1 - 7.4 6.8 10.6 1 9.5 1.1 3.2 3 1 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus TBPIP PF07106.8 ETO14211.1 - 9 5.8 16.4 1.6 8.2 2.5 2.7 2 1 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF708 PF05341.6 ETO14212.1 - 0.0026 17.5 0.6 0.0074 16.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF708) DUF904 PF06005.7 ETO14212.1 - 0.011 15.9 10.3 0.011 15.9 7.2 6.3 1 1 4 5 5 5 0 Protein of unknown function (DUF904) CENP-F_leu_zip PF10473.4 ETO14212.1 - 1.7 8.4 69.0 0.57 10.0 18.6 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Trypan_PARP PF05887.6 ETO14213.1 - 8.8e-05 22.3 1.2 0.00019 21.2 0.8 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) RNase_H2_suC PF08615.6 ETO14213.1 - 0.00069 19.4 1.8 0.98 9.2 0.0 2.8 2 1 0 2 2 2 2 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) CobT PF06213.7 ETO14213.1 - 0.0033 16.6 2.5 0.0033 16.6 1.7 2.1 2 0 0 2 2 2 1 Cobalamin biosynthesis protein CobT Mem_trans PF03547.13 ETO14213.1 - 0.0034 15.7 1.0 0.019 13.2 0.1 2.2 2 0 0 2 2 2 1 Membrane transport protein Neur_chan_memb PF02932.11 ETO14213.1 - 0.049 13.5 4.2 0.23 11.2 1.8 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.17 ETO14213.1 - 0.055 12.4 4.3 0.31 10.0 0.7 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter DUF2201_N PF13203.1 ETO14213.1 - 0.061 12.4 13.6 0.011 14.8 5.3 2.0 2 0 0 2 2 2 0 Putative metallopeptidase domain Eapp_C PF10238.4 ETO14213.1 - 0.11 12.4 18.1 0.44 10.4 0.1 2.5 2 0 0 2 2 2 0 E2F-associated phosphoprotein TRAP_alpha PF03896.11 ETO14213.1 - 0.85 8.5 11.9 9.7 5.0 0.0 2.3 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF2457 PF10446.4 ETO14213.1 - 2.9 6.5 17.7 0.49 9.0 6.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Raftlin PF15250.1 ETO14213.1 - 3.8 5.9 16.2 0.6 8.5 5.6 2.5 2 1 0 2 2 2 0 Raftlin DUF1510 PF07423.6 ETO14213.1 - 4.1 6.7 29.1 0.16 11.3 11.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF4637 PF15470.1 ETO14213.1 - 8.4 5.9 11.6 94 2.5 7.7 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4637) Fucose_iso_N2 PF07882.7 ETO14214.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain zf-C3HC4_2 PF13923.1 ETO14215.1 - 3.1e-11 43.0 16.4 6.2e-11 42.1 11.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO14215.1 - 4.4e-09 36.0 16.4 7.1e-09 35.3 11.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 ETO14215.1 - 1.1e-08 34.5 10.4 2e-08 33.7 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO14215.1 - 1.2e-07 31.2 14.7 2.1e-07 30.4 10.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO14215.1 - 1.3e-07 31.2 13.0 2.1e-07 30.5 9.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 ETO14215.1 - 5.6e-06 25.9 7.0 2.2e-05 24.0 4.8 2.1 1 1 1 2 2 2 1 RING-type zinc-finger U-box PF04564.10 ETO14215.1 - 3.7e-05 23.5 0.0 0.00035 20.4 0.0 2.1 2 0 0 2 2 2 1 U-box domain zf-rbx1 PF12678.2 ETO14215.1 - 0.00014 21.9 8.1 0.00026 21.0 5.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 ETO14215.1 - 0.0012 18.6 15.9 0.0023 17.7 11.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Rtf2 PF04641.7 ETO14215.1 - 0.0023 17.1 0.1 0.0034 16.6 0.1 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-P11 PF03854.9 ETO14215.1 - 0.015 14.7 10.2 0.03 13.7 7.0 1.5 1 0 0 1 1 1 0 P-11 zinc finger YajC PF02699.10 ETO14215.1 - 0.017 14.8 4.1 0.03 14.0 2.9 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit Prok-RING_4 PF14447.1 ETO14215.1 - 0.88 9.1 9.7 2.2 7.9 6.7 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.3 ETO14215.1 - 0.98 8.9 5.9 1.8 8.1 4.1 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Baculo_IE-1 PF05290.6 ETO14215.1 - 4 7.1 12.8 1.1 9.0 5.8 2.0 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) ERp29 PF07749.7 ETO14216.1 - 1.3e-21 77.0 0.5 2.3e-21 76.2 0.2 1.5 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain ERp29_N PF07912.8 ETO14216.1 - 8.7e-13 48.3 0.0 1.7e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 ERp29, N-terminal domain DUF2526 PF10735.4 ETO14216.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2526) SAM_2 PF07647.12 ETO14218.1 - 2.8e-06 27.0 0.1 4.7e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) TPR_11 PF13414.1 ETO14219.1 - 3.7e-15 55.3 18.9 1.1e-05 24.9 1.3 4.6 2 2 2 4 4 4 4 TPR repeat TPR_17 PF13431.1 ETO14219.1 - 5.9e-10 38.5 2.8 0.5 10.6 0.1 5.4 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO14219.1 - 1.2e-07 31.0 15.9 0.023 14.2 0.1 6.3 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO14219.1 - 3.7e-07 29.5 15.3 0.00066 19.3 0.2 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO14219.1 - 1.2e-05 25.5 10.0 0.00028 21.1 0.0 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO14219.1 - 1.6e-05 25.4 12.3 0.00065 20.3 0.4 3.9 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO14219.1 - 0.0013 19.1 6.1 0.036 14.6 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat XRN_N PF03159.13 ETO14221.1 - 0.012 15.0 3.0 0.018 14.4 1.1 2.0 2 0 0 2 2 2 0 XRN 5'-3' exonuclease N-terminus SPOB_a PF14689.1 ETO14221.1 - 0.059 12.9 3.9 0.51 9.9 0.5 3.7 2 1 1 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain BSP_II PF05432.6 ETO14221.1 - 0.23 10.6 14.9 0.4 9.9 10.4 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF2201_N PF13203.1 ETO14221.1 - 0.75 8.9 9.5 1.3 8.1 6.6 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Sporozoite_P67 PF05642.6 ETO14221.1 - 1.6 6.5 9.0 2.8 5.7 6.2 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2868 PF11067.3 ETO14221.1 - 2.5 7.1 3.6 11 5.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) Hid1 PF12722.2 ETO14221.1 - 5.4 4.5 8.9 7 4.1 6.2 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.17 ETO14221.1 - 6.3 5.7 6.2 12 4.8 4.3 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Ras PF00071.17 ETO14222.1 - 2e-16 59.8 0.8 9.2e-14 51.1 0.6 2.7 1 1 0 1 1 1 1 Ras family PPR_2 PF13041.1 ETO14223.1 - 1e-11 44.6 1.9 3.7e-08 33.2 0.9 3.0 3 0 0 3 3 3 2 PPR repeat family PPR PF01535.15 ETO14223.1 - 4.6e-06 26.2 2.0 0.058 13.3 0.6 3.7 3 0 0 3 3 3 2 PPR repeat Apc3 PF12895.2 ETO14223.1 - 0.00014 21.9 0.9 0.00059 19.9 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 PPR_3 PF13812.1 ETO14223.1 - 0.0006 19.8 1.2 4.1 7.9 0.1 4.0 4 0 0 4 4 4 2 Pentatricopeptide repeat domain TPR_12 PF13424.1 ETO14223.1 - 0.0013 18.6 0.7 1.5 8.8 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO14223.1 - 0.0084 15.6 0.1 1.1 9.0 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO14223.1 - 0.031 13.9 0.2 0.77 9.4 0.0 2.5 2 0 0 2 2 2 0 TPR repeat DUF3523 PF12037.3 ETO14223.1 - 0.042 12.8 0.3 0.085 11.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) TPR_2 PF07719.12 ETO14223.1 - 0.085 12.8 0.0 8 6.6 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR_1 PF12854.2 ETO14223.1 - 1.4 8.4 4.8 20 4.7 0.0 3.0 3 0 0 3 3 3 0 PPR repeat FAA_hydrolase PF01557.13 ETO14224.1 - 2.2e-05 24.0 0.0 2.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family SCAMP PF04144.8 ETO14225.1 - 3.1e-09 36.9 0.0 3.8e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 SCAMP family SKG6 PF08693.5 ETO14225.1 - 0.26 10.6 1.4 0.61 9.4 1.0 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain LRR_6 PF13516.1 ETO14226.1 - 3.9e-22 75.8 30.5 0.00071 19.3 0.3 10.4 11 1 0 11 11 11 7 Leucine Rich repeat LRR_4 PF12799.2 ETO14226.1 - 3.5e-12 45.6 21.6 5.8e-05 22.6 1.7 6.5 6 2 1 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO14226.1 - 2.2e-08 33.7 25.9 3.5e-05 23.4 0.5 6.9 4 2 2 6 6 6 4 Leucine rich repeat LRR_1 PF00560.28 ETO14226.1 - 9.2e-08 31.0 27.2 0.65 10.2 0.6 9.6 8 2 2 10 10 10 3 Leucine Rich Repeat LRR_7 PF13504.1 ETO14226.1 - 1.3e-06 27.5 15.3 5.2 7.7 0.3 8.1 7 0 0 7 7 7 2 Leucine rich repeat CreD PF06123.7 ETO14227.1 - 0.064 11.7 4.9 0.096 11.1 3.4 1.2 1 0 0 1 1 1 0 Inner membrane protein CreD Curto_V3 PF07436.6 ETO14227.1 - 0.47 10.6 2.9 0.92 9.6 0.2 2.5 3 0 0 3 3 3 0 Curtovirus V3 protein Porph_ging PF09697.5 ETO14227.1 - 1.6 8.9 8.7 0.49 10.5 2.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (Porph_ging) Polysacc_syn_2C PF08485.5 ETO14227.1 - 1.6 8.2 4.8 2.4 7.7 0.1 3.4 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein C-terminal Reo_sigmaC PF04582.7 ETO14229.1 - 5.7 6.0 10.2 9.1 5.3 1.5 2.8 1 1 2 3 3 2 0 Reovirus sigma C capsid protein TMCO5 PF14992.1 ETO14230.1 - 0.00025 20.2 36.8 0.00025 20.2 25.5 3.1 1 1 2 3 3 3 1 TMCO5 family Reo_sigmaC PF04582.7 ETO14230.1 - 0.0051 16.0 6.0 0.0051 16.0 4.2 3.7 1 1 1 4 4 4 2 Reovirus sigma C capsid protein bZIP_1 PF00170.16 ETO14230.1 - 0.0064 16.4 1.4 0.0064 16.4 1.0 8.8 4 2 4 9 9 9 3 bZIP transcription factor Myosin_tail_1 PF01576.14 ETO14230.1 - 1.1 6.8 79.2 0.045 11.4 5.5 4.1 2 1 1 4 4 4 0 Myosin tail Filament PF00038.16 ETO14230.1 - 1.4 8.3 72.0 0.081 12.3 33.6 3.3 1 1 1 2 2 2 0 Intermediate filament protein GAS PF13851.1 ETO14230.1 - 3.6 6.7 87.7 0.071 12.2 21.0 3.6 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding BicD PF09730.4 ETO14230.1 - 7 4.8 69.5 5.8 5.1 28.1 2.5 1 1 1 2 2 2 0 Microtubule-associated protein Bicaudal-D MSP7_C PF12948.2 ETO14231.1 - 0.0052 17.0 3.8 0.0052 17.0 2.6 2.7 1 1 1 2 2 1 1 MSP7-like protein C-terminal domain GAS PF13851.1 ETO14231.1 - 0.014 14.5 35.5 0.026 13.6 14.8 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding SlyX PF04102.7 ETO14231.1 - 0.029 14.7 20.8 0.08 13.3 4.9 3.5 1 1 3 4 4 4 0 SlyX ADIP PF11559.3 ETO14231.1 - 0.029 14.2 31.5 0.39 10.6 7.3 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding BCDHK_Adom3 PF10436.4 ETO14231.1 - 0.08 12.4 5.2 0.12 11.8 3.6 1.3 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Pecanex_C PF05041.10 ETO14231.1 - 0.11 11.5 3.2 0.14 11.1 1.4 1.4 1 1 0 1 1 1 0 Pecanex protein (C-terminus) Seadorna_VP6 PF07407.6 ETO14231.1 - 0.14 10.9 3.4 0.16 10.7 2.4 1.2 1 0 0 1 1 1 0 Seadornavirus VP6 protein Nup54 PF13874.1 ETO14231.1 - 0.16 11.6 19.5 0.25 10.9 3.3 2.6 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Sec20 PF03908.8 ETO14231.1 - 0.23 11.1 12.5 1.6 8.5 1.0 2.4 2 0 0 2 2 2 0 Sec20 GrpE PF01025.14 ETO14231.1 - 0.23 10.9 24.8 0.061 12.8 6.7 2.3 1 1 1 2 2 2 0 GrpE V_ATPase_I PF01496.14 ETO14231.1 - 0.28 8.9 17.7 0.39 8.5 12.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Reo_sigmaC PF04582.7 ETO14231.1 - 0.37 9.9 3.0 0.6 9.2 2.0 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Spc7 PF08317.6 ETO14231.1 - 0.8 8.3 28.6 4.1 5.9 19.0 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 ETO14231.1 - 0.89 9.1 26.9 4 6.9 18.7 1.9 1 1 0 1 1 1 0 IncA protein DegS PF05384.6 ETO14231.1 - 0.97 8.6 21.9 0.66 9.1 8.0 2.5 1 1 1 2 2 2 0 Sensor protein DegS CENP-Q PF13094.1 ETO14231.1 - 1.1 9.3 27.2 2.4 8.1 18.8 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF812 PF05667.6 ETO14231.1 - 1.1 7.6 27.8 3.1 6.1 19.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) ATG16 PF08614.6 ETO14231.1 - 1.7 8.4 28.1 1.3 8.8 8.6 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF3492 PF11997.3 ETO14231.1 - 2 7.9 7.9 3.2 7.2 5.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) Mod_r PF07200.8 ETO14231.1 - 2.2 8.2 26.8 0.85 9.5 7.5 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein LOH1CR12 PF10158.4 ETO14231.1 - 2.3 8.0 15.0 0.56 9.9 2.2 2.2 1 1 1 2 2 2 0 Tumour suppressor protein CCDC92 PF14916.1 ETO14231.1 - 2.5 7.7 13.7 4.1 7.0 0.6 3.2 2 2 0 2 2 2 0 Coiled-coil domain of unknown function TMF_TATA_bd PF12325.3 ETO14231.1 - 2.7 7.7 28.4 0.36 10.5 12.3 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Fzo_mitofusin PF04799.8 ETO14231.1 - 3 7.1 15.6 2.4 7.5 4.2 2.2 2 0 0 2 2 2 0 fzo-like conserved region TBPIP PF07106.8 ETO14231.1 - 3.7 7.0 29.8 1.8 8.0 5.6 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NPV_P10 PF05531.7 ETO14231.1 - 3.8 7.8 16.1 2.3 8.5 2.7 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein IL2 PF00715.12 ETO14231.1 - 5.1 6.7 9.5 7.9 6.2 6.5 1.5 1 1 0 1 1 1 0 Interleukin 2 DUF4164 PF13747.1 ETO14231.1 - 5.2 7.2 16.0 0.69 10.0 1.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) PhoU PF01895.14 ETO14231.1 - 6.1 7.3 11.5 0.78 10.2 1.7 2.3 1 1 1 2 2 2 0 PhoU domain DUF4337 PF14235.1 ETO14231.1 - 7.4 6.3 25.3 1.5 8.6 6.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) DUF3683 PF12447.3 ETO14231.1 - 8.2 6.3 10.5 9 6.1 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3683) Acetyltransf_11 PF13720.1 ETO14231.1 - 8.6 6.6 8.9 1.1 9.4 0.5 3.0 1 1 2 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DivIC PF04977.10 ETO14231.1 - 8.7 5.9 32.2 3.2 7.2 6.1 4.1 1 1 2 3 3 3 0 Septum formation initiator FHIPEP PF00771.15 ETO14232.1 - 0.012 14.0 0.5 0.012 14.0 0.3 1.6 2 0 0 2 2 2 0 FHIPEP family GRIM-19 PF06212.7 ETO14232.1 - 0.3 10.8 1.9 5.3 6.7 0.1 2.3 2 0 0 2 2 2 0 GRIM-19 protein DUF972 PF06156.8 ETO14232.1 - 0.92 9.8 27.7 1.1 9.5 5.5 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 ETO14232.1 - 2.2 6.0 21.4 0.12 10.1 3.8 2.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family bZIP_1 PF00170.16 ETO14232.1 - 2.7 8.0 23.0 3 7.8 3.7 4.4 4 0 0 4 4 4 0 bZIP transcription factor APG6 PF04111.7 ETO14232.1 - 3.4 6.6 38.2 0.41 9.6 10.3 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF651 PF04895.7 ETO14232.1 - 3.6 7.2 6.5 2.6 7.6 0.8 2.6 2 0 0 2 2 2 0 Archaeal protein of unknown function (DUF651) SAC3_GANP PF03399.11 ETO14234.1 - 0.00094 18.7 1.5 0.025 14.1 0.2 2.1 2 0 0 2 2 2 2 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF687 PF05095.7 ETO14234.1 - 0.0081 14.5 0.2 0.01 14.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF687) CCDC92 PF14916.1 ETO14234.1 - 0.044 13.3 2.2 0.11 12.0 1.5 1.7 1 0 0 1 1 1 0 Coiled-coil domain of unknown function PDZ PF00595.19 ETO14235.1 - 1.1e-05 25.4 0.0 3.3e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) zf-Apc11 PF12861.2 ETO14235.1 - 0.011 15.5 4.0 0.029 14.1 2.8 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn-ribbon_8 PF09723.5 ETO14235.1 - 0.017 15.1 0.4 1 9.3 0.0 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-IS66 PF13005.2 ETO14235.1 - 0.043 13.7 1.0 3.9 7.5 0.0 2.4 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 PDZ_2 PF13180.1 ETO14235.1 - 0.056 13.3 0.0 0.18 11.7 0.0 1.9 1 0 0 1 1 1 0 PDZ domain UPF0547 PF10571.4 ETO14235.1 - 1.3 8.7 8.8 17 5.2 6.1 2.3 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 zinc_ribbon_5 PF13719.1 ETO14235.1 - 1.4 8.5 4.6 0.25 10.9 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-C4_Topoisom PF01396.14 ETO14235.1 - 5 6.7 8.6 5.3 6.6 0.2 2.8 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger dDENN PF03455.14 ETO14236.1 - 4.5e-06 26.6 2.2 4.5e-06 26.6 1.5 2.7 2 1 0 2 2 2 1 dDENN domain YMF19 PF02326.10 ETO14236.1 - 0.13 12.8 2.2 6 7.5 0.2 3.0 3 0 0 3 3 3 0 Plant ATP synthase F0 Kelch_6 PF13964.1 ETO14237.1 - 3.5e-11 42.7 8.3 1.4e-05 25.0 0.2 4.5 3 1 1 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO14237.1 - 4.4e-10 39.4 0.9 6.8e-06 26.1 0.0 4.5 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO14237.1 - 1.7e-08 34.2 5.6 0.0071 16.2 0.5 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 ETO14237.1 - 3.5e-08 32.8 11.8 0.0011 18.4 0.2 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO14237.1 - 4.3e-08 32.7 0.9 4e-05 23.2 0.1 3.6 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO14237.1 - 0.084 12.6 4.8 0.97 9.3 0.1 3.9 4 0 0 4 4 4 0 Kelch motif CarboxypepD_reg PF13620.1 ETO14238.1 - 2.2e-13 50.0 0.0 5.6e-07 29.5 0.0 3.2 3 1 0 3 3 3 2 Carboxypeptidase regulatory-like domain Y_Y_Y PF07495.8 ETO14238.1 - 0.0038 16.9 0.0 0.0093 15.6 0.0 1.6 1 0 0 1 1 1 1 Y_Y_Y domain Cna_B PF05738.8 ETO14238.1 - 0.0049 16.6 0.1 0.02 14.6 0.0 2.0 2 0 0 2 2 2 1 Cna protein B-type domain fn3_3 PF14686.1 ETO14238.1 - 0.084 13.0 0.2 15 5.7 0.0 2.7 2 1 0 2 2 2 0 Polysaccharide lyase family 4, domain II Dioxygenase_C PF00775.16 ETO14238.1 - 0.13 11.5 0.1 3.4 6.9 0.1 2.6 2 1 0 2 2 2 0 Dioxygenase APG6 PF04111.7 ETO14238.1 - 0.26 10.2 16.8 0.48 9.4 11.7 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 EMP24_GP25L PF01105.19 ETO14238.1 - 0.47 10.1 0.0 0.47 10.1 0.0 3.0 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD MAP7 PF05672.6 ETO14238.1 - 3.4 7.0 30.3 6 6.2 21.0 1.3 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family V_ATPase_I PF01496.14 ETO14238.1 - 5.2 4.7 7.3 7.5 4.2 5.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 ETO14238.1 - 8.6 5.9 14.7 16 5.0 10.2 1.4 1 0 0 1 1 1 0 IncA protein WD40 PF00400.27 ETO14239.1 - 8.8e-47 155.3 10.6 1.3e-12 47.0 0.2 5.3 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 ETO14239.1 - 2.2e-07 30.7 0.0 0.031 14.0 0.0 2.9 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO14239.1 - 1e-05 24.0 0.2 0.017 13.4 0.0 2.7 1 1 2 3 3 3 3 Cytochrome D1 heme domain BBS2_Mid PF14783.1 ETO14239.1 - 0.00016 21.3 2.8 0.26 11.0 0.2 3.9 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 ETO14239.1 - 0.0008 18.2 3.5 0.54 8.9 0.6 3.3 1 1 0 2 2 2 2 Nup133 N terminal like Nup160 PF11715.3 ETO14239.1 - 0.0019 16.3 1.8 3 5.8 0.0 3.7 2 1 2 4 4 4 1 Nucleoporin Nup120/160 PD40 PF07676.7 ETO14239.1 - 0.0049 16.4 0.1 2.8 7.6 0.0 3.0 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.9 ETO14239.1 - 0.017 13.9 0.2 0.17 10.6 0.0 1.9 1 1 1 2 2 2 0 Coatomer WD associated region Proteasome_A_N PF10584.4 ETO14239.1 - 0.095 12.0 0.7 15 5.0 0.0 2.9 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature KSR1-SAM PF13543.1 ETO14240.1 - 0.0017 18.1 0.2 0.003 17.3 0.1 1.4 1 1 0 1 1 1 1 SAM like domain present in kinase suppressor RAS 1 RNase_H2-Ydr279 PF09468.5 ETO14240.1 - 0.0094 15.1 9.7 0.012 14.8 6.7 1.2 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Ste50p-SAM PF09235.5 ETO14240.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif SAM_1 PF00536.25 ETO14240.1 - 0.069 13.3 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) GAGA_bind PF06217.7 ETO14240.1 - 0.59 10.0 7.4 0.61 10.0 5.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DDHD PF02862.12 ETO14240.1 - 4.6 6.9 6.8 4.9 6.8 4.7 1.1 1 0 0 1 1 1 0 DDHD domain Ras PF00071.17 ETO14241.1 - 1.1e-20 73.6 0.1 1.3e-20 73.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.16 ETO14241.1 - 0.001 18.3 0.0 0.0013 17.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 ETO14241.1 - 0.0025 18.3 0.0 0.0037 17.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 ETO14241.1 - 0.0097 15.3 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain YIF1 PF03878.10 ETO14241.1 - 0.092 11.8 1.0 0.12 11.5 0.7 1.1 1 0 0 1 1 1 0 YIF1 SAGA-Tad1 PF12767.2 ETO14242.1 - 0.054 13.1 5.6 0.07 12.7 3.9 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF3541 PF12060.3 ETO14242.1 - 0.055 12.7 6.3 0.079 12.2 2.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3541) Med8 PF10232.4 ETO14242.1 - 0.07 12.6 4.9 0.095 12.2 3.4 1.3 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 K_trans PF02705.11 ETO14242.1 - 0.68 8.2 2.2 0.83 7.9 1.5 1.1 1 0 0 1 1 1 0 K+ potassium transporter Cytochrom_C552 PF02335.10 ETO14243.1 - 0.01 14.5 0.1 0.018 13.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c552 WD40 PF00400.27 ETO14244.1 - 2.4e-20 71.6 17.8 1.8e-11 43.4 0.2 3.6 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO14244.1 - 0.034 12.3 3.8 3.3 5.7 0.1 2.8 1 1 2 3 3 3 0 Nucleoporin Nup120/160 KduI PF04962.7 ETO14244.1 - 0.036 13.1 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 KduI/IolB family WD40 PF00400.27 ETO14245.1 - 2.9e-63 207.6 19.6 8.2e-13 47.6 0.2 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO14245.1 - 2.5e-12 45.7 4.4 0.031 12.4 0.0 5.2 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Kelch_1 PF01344.20 ETO14245.1 - 5.2e-05 22.6 8.8 0.16 11.5 0.3 5.3 6 0 0 6 6 6 2 Kelch motif PQQ_2 PF13360.1 ETO14245.1 - 0.00014 21.4 0.2 0.0014 18.1 0.2 2.8 1 1 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO14245.1 - 0.00099 17.5 0.1 0.031 12.5 0.0 2.6 1 1 2 3 3 3 2 Cytochrome D1 heme domain Kelch_4 PF13418.1 ETO14245.1 - 0.0013 18.4 7.9 0.45 10.3 1.2 3.8 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO14245.1 - 0.0017 18.4 11.0 1.4 9.2 0.0 6.2 6 0 0 6 6 6 1 Kelch motif Kelch_2 PF07646.10 ETO14245.1 - 0.0023 17.6 4.9 2.4 8.0 0.2 5.3 5 1 0 5 5 5 1 Kelch motif Kelch_5 PF13854.1 ETO14245.1 - 0.033 14.1 4.1 62 3.7 0.0 4.7 4 0 0 4 4 4 0 Kelch motif PD40 PF07676.7 ETO14245.1 - 0.3 10.8 12.2 6.5 6.5 0.1 4.7 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF239 PF03080.10 ETO14246.1 - 0.38 9.8 0.0 0.38 9.8 0.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF239) DUF3807 PF12720.2 ETO14246.1 - 2 8.5 11.6 3.1 7.9 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF2009 PF09418.5 ETO14247.1 - 0.059 12.1 1.5 0.071 11.8 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) DUF2718 PF10918.3 ETO14247.1 - 0.39 10.7 2.5 0.5 10.4 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2718) Vfa1 PF08432.5 ETO14247.1 - 1.1 9.2 11.1 1.5 8.8 7.7 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Sporozoite_P67 PF05642.6 ETO14247.1 - 4.7 4.9 6.1 6 4.6 4.2 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PRKCSH_1 PF13015.1 ETO14248.1 - 1.6e-07 30.9 0.6 2.4e-07 30.3 0.4 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 ETO14248.1 - 0.00053 20.7 9.5 0.00063 20.4 1.7 3.1 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein GAGA_bind PF06217.7 ETO14249.1 - 0.18 11.7 38.0 0.42 10.5 13.9 2.3 2 0 0 2 2 2 0 GAGA binding protein-like family SprA-related PF12118.3 ETO14249.1 - 2.2 7.5 48.9 0.59 9.4 13.7 2.2 2 0 0 2 2 2 0 SprA-related family CDC27 PF09507.5 ETO14249.1 - 3.4 6.7 50.1 1.7 7.8 16.7 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 G-gamma PF00631.17 ETO14253.1 - 0.00062 19.4 1.6 0.001 18.7 0.2 2.0 2 1 0 2 2 2 1 GGL domain PI3Ka PF00613.15 ETO14253.1 - 0.0068 15.5 7.0 0.15 11.1 1.0 2.3 1 1 1 2 2 2 2 Phosphoinositide 3-kinase family, accessory domain (PIK domain) UvrD_C PF13361.1 ETO14253.1 - 0.017 14.5 11.6 0.024 14.1 8.1 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain ETC_C1_NDUFA5 PF04716.9 ETO14253.1 - 0.026 14.0 1.5 0.078 12.5 0.1 2.5 2 0 0 2 2 2 0 ETC complex I subunit conserved region HPPK PF01288.15 ETO14253.1 - 0.028 14.1 1.9 0.059 13.0 1.3 1.6 1 0 0 1 1 1 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) PIN_2 PF10130.4 ETO14253.1 - 0.051 13.6 4.4 0.084 12.9 2.8 1.6 1 1 0 1 1 1 0 PIN domain DUF2265 PF10023.4 ETO14253.1 - 0.097 11.7 3.5 0.17 11.0 2.5 1.4 1 1 0 1 1 1 0 Predicted aminopeptidase (DUF2265) DUF2621 PF11084.3 ETO14253.1 - 0.13 11.9 2.3 0.17 11.5 1.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2621) NLE PF08154.7 ETO14253.1 - 0.21 11.6 3.4 1.4 9.0 0.1 2.9 2 1 1 3 3 3 0 NLE (NUC135) domain FUSC-like PF12805.2 ETO14253.1 - 0.24 10.3 2.1 0.35 9.7 1.4 1.4 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS DUF19 PF01579.13 ETO14253.1 - 0.36 10.8 8.3 0.57 10.1 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF19) TMPIT PF07851.8 ETO14253.1 - 0.39 9.7 13.2 0.35 9.9 8.5 1.5 1 1 0 1 1 1 0 TMPIT-like protein Mor PF08765.6 ETO14253.1 - 0.53 10.0 3.6 0.48 10.2 0.1 2.2 2 0 0 2 2 2 0 Mor transcription activator family zf-C4H2 PF10146.4 ETO14253.1 - 0.57 10.1 19.8 0.18 11.8 4.0 2.0 1 1 1 2 2 2 0 Zinc finger-containing protein zf-C4pol PF14260.1 ETO14253.1 - 0.86 9.6 4.7 2.6 8.0 2.5 2.2 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta BSD PF03909.12 ETO14253.1 - 1.7 8.4 6.3 8 6.2 0.2 3.3 3 0 0 3 3 3 0 BSD domain DUF3505 PF12013.3 ETO14253.1 - 2.4 8.4 5.2 12 6.2 2.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3505) DUF148 PF02520.12 ETO14253.1 - 3.2 7.5 20.3 0.28 11.0 8.6 2.5 2 1 1 3 3 3 0 Domain of unknown function DUF148 PRCC PF10253.4 ETO14253.1 - 4.1 8.0 9.8 1.6 9.3 4.2 1.9 1 1 1 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting CWC25 PF12542.3 ETO14253.1 - 4.5 7.7 15.2 48 4.4 10.5 2.3 1 1 1 2 2 2 0 Pre-mRNA splicing factor Lge1 PF11488.3 ETO14253.1 - 7 6.9 13.0 0.45 10.7 1.2 2.9 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 RNA_pol_Rpb1_5 PF04998.12 ETO14254.1 - 0.1 11.8 0.2 0.14 11.4 0.2 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 zf-C3HC4_4 PF15227.1 ETO14254.1 - 0.24 11.3 2.7 0.58 10.0 1.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING IBR PF01485.16 ETO14254.1 - 0.52 10.2 5.2 1.2 9.0 3.6 1.6 1 0 0 1 1 1 0 IBR domain Phage_int_SAM_5 PF13102.1 ETO14254.1 - 1.2 9.1 7.9 0.43 10.5 0.7 3.0 2 1 1 3 3 3 0 Phage integrase SAM-like domain Toxin_67 PF15545.1 ETO14256.1 - 0.0065 16.3 2.3 0.013 15.3 1.6 1.5 1 0 0 1 1 1 1 Putative toxin 67 Selenoprotein_S PF06936.6 ETO14256.1 - 5.7 6.4 8.5 11 5.5 5.9 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) ATP-synt_F PF01990.12 ETO14257.1 - 2e-24 85.7 0.0 4.2e-24 84.7 0.0 1.6 1 1 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Alph_Pro_TM PF09608.5 ETO14259.1 - 0.2 11.1 2.7 0.24 10.9 1.9 1.1 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) WAK PF08488.6 ETO14259.1 - 0.26 11.6 2.0 0.41 10.9 0.9 1.7 1 1 0 1 1 1 0 Wall-associated kinase SYF2 PF08231.7 ETO14259.1 - 0.41 10.7 9.3 0.11 12.5 3.8 1.8 1 1 1 2 2 2 0 SYF2 splicing factor DUF874 PF05917.6 ETO14259.1 - 3 6.6 10.1 3.7 6.3 7.0 1.1 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) G-alpha PF00503.15 ETO14261.1 - 8.8e-55 185.9 2.2 1.1e-54 185.5 1.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO14261.1 - 8.4e-12 44.6 0.1 1.4e-07 30.8 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETO14261.1 - 7.3e-05 22.6 0.2 0.052 13.5 0.1 2.4 2 1 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 ETO14261.1 - 0.056 13.9 0.0 4.2 7.9 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein Gtr1_RagA PF04670.7 ETO14261.1 - 0.18 10.9 1.2 29 3.7 0.0 3.6 4 0 0 4 4 4 0 Gtr1/RagA G protein conserved region Thioredoxin_7 PF13899.1 ETO14262.1 - 3.3e-07 30.2 0.2 8.3e-07 28.9 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like DUF3972 PF13118.1 ETO14264.1 - 0.025 14.6 0.1 0.075 13.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) Arm PF00514.18 ETO14265.1 - 7.3e-22 76.3 4.6 5.9e-12 44.9 0.5 3.4 3 0 0 3 3 3 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 ETO14265.1 - 1.2e-11 44.7 0.2 2.4e-10 40.5 0.1 2.6 1 1 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.1 ETO14265.1 - 8.8e-10 38.7 0.1 0.00012 22.4 0.1 2.7 2 0 0 2 2 2 2 HEAT-like repeat HEAT PF02985.17 ETO14265.1 - 6e-08 32.1 0.8 0.00021 21.1 0.1 3.4 3 0 0 3 3 3 2 HEAT repeat Adaptin_N PF01602.15 ETO14265.1 - 0.0016 16.8 0.0 0.007 14.7 0.0 1.9 1 1 0 1 1 1 1 Adaptin N terminal region Proteasom_PSMB PF10508.4 ETO14265.1 - 0.0087 14.3 0.1 0.016 13.4 0.0 1.5 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit CLASP_N PF12348.3 ETO14265.1 - 0.016 14.5 0.1 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 CLASP N terminal Hormone_1 PF00103.15 ETO14265.1 - 0.024 13.9 3.3 2.7 7.2 0.0 2.5 3 0 0 3 3 3 0 Somatotropin hormone family HEAT_PBS PF03130.11 ETO14265.1 - 0.076 13.5 0.1 0.34 11.5 0.1 2.2 1 1 0 1 1 1 0 PBS lyase HEAT-like repeat DUF2505 PF10698.4 ETO14265.1 - 0.089 12.2 0.1 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2505) adh_short PF00106.20 ETO14267.1 - 3.8e-13 49.7 0.0 5.8e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETO14267.1 - 2.9e-05 23.7 0.0 7.9e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETO14267.1 - 0.00039 20.2 0.3 0.00068 19.4 0.1 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase CobT PF06213.7 ETO14267.1 - 0.017 14.2 6.4 0.025 13.7 4.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.9 ETO14267.1 - 2.1 6.2 12.3 0.05 11.6 4.0 1.5 2 0 0 2 2 2 0 CDC45-like protein Nucleoplasmin PF03066.10 ETO14267.1 - 6.7 6.2 13.2 12 5.4 9.1 1.4 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 ETO14267.1 - 7.6 6.8 16.7 16 5.7 11.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pkinase PF00069.20 ETO14269.1 - 0.0028 16.8 0.3 0.076 12.1 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase PF00069.20 ETO14270.1 - 7.7e-36 123.5 0.1 1.1e-35 123.0 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO14270.1 - 9.3e-24 83.8 0.2 1.5e-23 83.1 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO14270.1 - 5.4e-07 28.8 0.4 1.7e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 ETO14270.1 - 0.0015 18.3 0.0 0.0021 17.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 ETO14270.1 - 0.0025 16.7 1.5 0.0036 16.1 0.1 1.9 2 0 0 2 2 2 1 Seadornavirus VP7 DUF3947 PF13135.1 ETO14271.1 - 1.2 9.3 6.3 0.19 11.9 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3947) AcetylCoA_hyd_C PF13336.1 ETO14272.1 - 4.2e-58 195.3 0.1 9.1e-47 158.5 0.1 2.2 2 0 0 2 2 2 2 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.10 ETO14272.1 - 4.7e-21 75.4 0.0 9.9e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain Ras PF00071.17 ETO14273.1 - 4.1e-51 172.5 1.2 1.7e-50 170.5 0.9 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 ETO14273.1 - 3.6e-14 53.2 1.0 9.3e-14 51.9 0.0 2.0 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO14273.1 - 4.2e-10 39.1 1.0 2.1e-09 36.8 0.7 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETO14273.1 - 0.00012 22.0 1.9 0.0014 18.5 1.3 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 ETO14273.1 - 0.00035 20.0 0.2 0.00076 18.9 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 ETO14273.1 - 0.012 14.7 0.0 0.034 13.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 FeoB_N PF02421.13 ETO14273.1 - 0.02 14.1 0.7 1.7 7.9 0.0 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_22 PF13401.1 ETO14273.1 - 0.024 14.7 0.0 0.056 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain SpoIIID PF12116.3 ETO14273.1 - 0.089 12.7 0.0 0.089 12.7 0.0 2.6 3 0 0 3 3 3 0 Stage III sporulation protein D ABC_tran PF00005.22 ETO14273.1 - 0.092 13.0 1.2 0.39 11.0 0.6 2.2 1 1 0 2 2 2 0 ABC transporter AAA_29 PF13555.1 ETO14273.1 - 0.098 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 ETO14273.1 - 0.11 12.5 0.1 0.23 11.4 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain Hpr_kinase_C PF07475.7 ETO14273.1 - 0.35 10.1 3.6 3.7 6.8 0.0 3.5 3 1 1 4 4 4 0 HPr Serine kinase C-terminal domain NT-C2 PF10358.4 ETO14273.1 - 3.3 7.1 13.1 1.2 8.6 5.6 2.4 2 1 0 2 2 2 0 N-terminal C2 in EEIG1 and EHBP1 proteins Abhydrolase_6 PF12697.2 ETO14275.1 - 5.7e-09 36.1 0.0 9.9e-09 35.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 ETO14275.1 - 0.00011 21.6 0.0 0.00017 21.1 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 ETO14275.1 - 0.00012 21.8 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 ETO14275.1 - 0.00079 19.0 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.15 ETO14275.1 - 0.0036 17.5 0.0 0.0051 17.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Chlorophyllase2 PF12740.2 ETO14275.1 - 0.0053 15.6 0.0 0.0071 15.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_3 PF07859.8 ETO14275.1 - 0.01 15.4 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold NodS PF05401.6 ETO14275.1 - 0.026 13.9 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) DUF2974 PF11187.3 ETO14275.1 - 0.04 13.2 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF915 PF06028.6 ETO14275.1 - 0.056 12.5 0.0 0.083 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Ser_hydrolase PF06821.8 ETO14275.1 - 0.099 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_1 PF00561.15 ETO14275.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold LTD PF00932.14 ETO14276.1 - 0.0026 17.8 0.0 0.0047 17.0 0.0 1.4 1 0 0 1 1 1 1 Lamin Tail Domain PPR_2 PF13041.1 ETO14277.1 - 4.2e-08 33.0 8.7 0.028 14.3 0.7 5.6 4 1 2 6 6 6 3 PPR repeat family PPR PF01535.15 ETO14277.1 - 4.9e-05 23.0 9.2 7 6.8 0.0 6.3 6 0 0 6 6 6 2 PPR repeat PPR_1 PF12854.2 ETO14277.1 - 0.00015 21.1 7.2 1.2 8.6 0.0 6.1 6 0 0 6 6 6 2 PPR repeat ECSIT PF06239.6 ETO14277.1 - 0.036 12.9 1.1 0.11 11.3 0.0 2.0 2 0 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway PPR_3 PF13812.1 ETO14277.1 - 0.062 13.6 6.0 45 4.6 0.0 6.4 7 0 0 7 7 7 0 Pentatricopeptide repeat domain Actin PF00022.14 ETO14278.1 - 2.4e-85 286.3 0.0 2.7e-85 286.1 0.0 1.0 1 0 0 1 1 1 1 Actin ATP-grasp_2 PF08442.5 ETO14279.1 - 1.5e-59 200.7 4.4 8.2e-43 146.1 0.0 3.3 2 1 1 3 3 3 3 ATP-grasp domain Ligase_CoA PF00549.14 ETO14279.1 - 1.1e-26 93.2 1.0 2e-26 92.4 0.7 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 ETO14279.1 - 0.0093 15.2 0.6 0.28 10.3 0.0 2.5 2 1 0 2 2 2 1 ATP-grasp domain zf-RING_5 PF14634.1 ETO14280.1 - 0.0074 16.0 2.7 0.031 14.0 2.0 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 ETO14280.1 - 0.01 15.4 1.4 0.089 12.4 1.3 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETO14280.1 - 0.018 15.1 1.3 0.04 14.0 0.9 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 ETO14280.1 - 0.04 13.4 0.8 0.18 11.3 0.1 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.1 ETO14280.1 - 0.1 12.6 3.9 0.18 11.8 0.6 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO14280.1 - 0.3 10.8 4.1 2.1 8.0 2.9 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO14280.1 - 0.7 9.7 6.5 3.7 7.4 4.5 2.3 1 1 1 2 2 2 0 Ring finger domain Helicase_C PF00271.26 ETO14281.1 - 4.5e-20 71.2 0.0 7.8e-20 70.5 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 ETO14281.1 - 3.8e-07 29.5 1.7 3e-05 23.4 0.3 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4217) PAD_N PF08526.5 ETO14281.1 - 0.063 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) N-terminal domain Glyco_transf_22 PF03901.12 ETO14282.1 - 8.2e-77 258.9 28.9 1.1e-76 258.5 20.0 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Phospholip_B PF04916.8 ETO14283.1 - 3.8e-89 299.2 6.0 5.8e-89 298.6 4.2 1.3 1 1 0 1 1 1 1 Phospholipase B CDC45 PF02724.9 ETO14284.1 - 0.0017 16.4 1.9 0.0018 16.3 1.3 1.0 1 0 0 1 1 1 1 CDC45-like protein Vfa1 PF08432.5 ETO14284.1 - 0.002 18.1 8.3 0.0023 18.0 5.7 1.2 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 SR-25 PF10500.4 ETO14284.1 - 0.22 10.9 9.2 0.24 10.8 6.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein U79_P34 PF03064.11 ETO14284.1 - 0.9 9.0 8.0 0.95 8.9 5.6 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF2956 PF11169.3 ETO14284.1 - 2.8 7.9 11.1 0.56 10.1 5.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) SPRY PF00622.23 ETO14285.1 - 3e-12 46.6 0.1 6.8e-12 45.5 0.1 1.6 1 0 0 1 1 1 1 SPRY domain zf-RanBP PF00641.13 ETO14285.1 - 2e-06 26.8 3.2 5.1e-06 25.4 2.2 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others FCH PF00611.18 ETO14286.1 - 0.00046 20.3 3.1 0.00046 20.3 2.1 3.0 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Telomere_reg-2 PF10193.4 ETO14286.1 - 0.53 10.5 5.2 0.21 11.8 1.1 2.2 2 0 0 2 2 2 0 Telomere length regulation protein C2 PF00168.25 ETO14286.1 - 3.7 7.4 6.4 0.18 11.6 0.4 1.8 2 0 0 2 2 2 0 C2 domain Glyco_transf_10 PF00852.14 ETO14288.1 - 4.5e-55 186.6 0.3 3.9e-54 183.5 0.2 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) DUF4339 PF14237.1 ETO14289.1 - 7.2e-06 25.4 0.3 1.6e-05 24.4 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4339) Kelch_1 PF01344.20 ETO14289.1 - 0.054 13.0 1.0 0.054 13.0 0.7 2.6 3 0 0 3 3 3 0 Kelch motif TFIIIC_delta PF12657.2 ETO14289.1 - 0.078 12.6 3.5 0.18 11.4 2.4 1.7 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term SRP54 PF00448.17 ETO14290.1 - 1.6e-75 252.9 0.4 2.9e-75 252.0 0.3 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 ETO14290.1 - 4.7e-22 78.2 2.5 4.7e-22 78.2 1.7 3.3 2 1 2 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.14 ETO14290.1 - 2.6e-08 33.8 2.1 2.6e-08 33.8 1.5 2.3 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain CbiA PF01656.18 ETO14290.1 - 3.2e-06 26.6 1.7 9.8e-06 25.1 0.1 2.6 3 1 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.14 ETO14290.1 - 4.6e-06 26.1 5.6 2.3e-05 23.9 2.4 2.8 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 ETO14290.1 - 1.3e-05 26.0 0.1 4.7e-05 24.1 0.0 2.0 2 0 0 2 2 1 1 AAA domain MobB PF03205.9 ETO14290.1 - 7.4e-05 22.4 0.5 0.00026 20.6 0.0 2.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 ETO14290.1 - 0.00022 21.1 0.0 0.00054 19.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 ETO14290.1 - 0.00036 19.3 0.0 0.00088 18.1 0.0 1.6 1 0 0 1 1 1 1 ArgK protein AAA_31 PF13614.1 ETO14290.1 - 0.00055 19.8 0.7 1.9 8.3 0.0 3.4 4 0 0 4 4 3 2 AAA domain SRPRB PF09439.5 ETO14290.1 - 0.0037 16.5 0.8 1.9 7.6 0.0 2.5 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 ETO14290.1 - 0.0068 16.4 0.0 0.046 13.7 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 ETO14290.1 - 0.012 15.8 3.0 0.031 14.5 0.1 3.1 2 1 1 3 3 3 0 AAA domain AAA_22 PF13401.1 ETO14290.1 - 0.013 15.6 0.1 0.056 13.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 ETO14290.1 - 0.018 14.8 0.5 0.15 11.8 0.0 2.4 2 0 0 2 2 2 0 Dynamin family 6PF2K PF01591.13 ETO14290.1 - 0.024 13.7 0.0 0.21 10.6 0.0 2.3 2 0 0 2 2 2 0 6-phosphofructo-2-kinase APS_kinase PF01583.15 ETO14290.1 - 0.041 13.5 0.0 0.094 12.3 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase PduV-EutP PF10662.4 ETO14290.1 - 0.045 13.2 0.6 2.4 7.6 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF955 PF06114.8 ETO14290.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF955) AAA_23 PF13476.1 ETO14290.1 - 0.19 12.0 2.9 0.75 10.0 1.4 2.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 ETO14290.1 - 0.42 10.8 3.1 3.7 7.7 0.5 3.5 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Plasmodium_Vir PF05795.6 ETO14291.1 - 0.015 14.5 1.8 0.019 14.1 1.3 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein APC_CDC26 PF10471.4 ETO14292.1 - 0.1 13.3 0.6 0.1 13.3 0.4 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 PPV_E1_N PF00524.13 ETO14293.1 - 0.025 14.7 1.9 0.044 13.9 1.3 1.4 1 0 0 1 1 1 0 E1 Protein, N terminal domain 7TMR-HDED PF07697.6 ETO14293.1 - 0.05 13.3 0.3 0.051 13.2 0.2 1.2 1 0 0 1 1 1 0 7TM-HD extracellular Myosin_head PF00063.16 ETO14295.1 - 1.3e-137 459.7 13.9 6.6e-115 384.7 2.7 2.9 3 1 0 3 3 3 2 Myosin head (motor domain) MyTH4 PF00784.12 ETO14295.1 - 2.2e-27 95.2 0.0 8.5e-27 93.3 0.0 2.1 1 0 0 1 1 1 1 MyTH4 domain DUF1768 PF08719.6 ETO14295.1 - 0.36 10.5 5.6 0.084 12.6 0.7 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1768) Metallophos PF00149.23 ETO14297.1 - 1.2e-09 37.9 0.7 1.4e-09 37.6 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 ETO14297.1 - 2e-08 34.2 0.1 2.4e-08 33.9 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Epimerase_2 PF02350.14 ETO14297.1 - 0.046 12.4 0.1 0.057 12.1 0.1 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase MFS_2 PF13347.1 ETO14298.1 - 0.015 13.7 1.0 0.019 13.3 0.7 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein ubiquitin PF00240.18 ETO14300.1 - 0.036 13.4 0.4 0.082 12.3 0.3 1.6 1 0 0 1 1 1 0 Ubiquitin family WD40 PF00400.27 ETO14301.1 - 6.4e-79 257.2 20.9 1.7e-12 46.6 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO14301.1 - 9.4e-11 41.7 0.4 2.3e-05 24.1 0.0 3.5 1 1 4 5 5 5 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO14301.1 - 6.4e-10 37.7 6.2 0.03 12.4 0.3 4.5 1 1 4 5 5 5 4 Nucleoporin Nup120/160 Proteasome_A_N PF10584.4 ETO14301.1 - 5.8e-06 25.5 11.9 1.1 8.5 0.1 6.8 7 0 0 7 7 7 2 Proteasome subunit A N-terminal signature Cytochrom_D1 PF02239.11 ETO14301.1 - 9.1e-06 24.2 0.3 0.14 10.4 0.0 3.3 1 1 2 3 3 3 2 Cytochrome D1 heme domain PD40 PF07676.7 ETO14301.1 - 9.5e-05 21.9 6.5 7.4 6.3 0.1 6.0 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat Methyltransf_3 PF01596.12 ETO14301.1 - 0.0012 17.9 0.0 1.9 7.4 0.0 3.8 2 1 1 4 4 4 1 O-methyltransferase Mid2 PF04478.7 ETO14301.1 - 0.0029 17.0 0.7 0.75 9.2 0.0 3.6 1 1 1 3 3 3 1 Mid2 like cell wall stress sensor PQQ_2 PF13360.1 ETO14301.1 - 0.0031 17.0 0.2 0.012 15.1 0.1 2.0 1 1 0 1 1 1 1 PQQ-like domain DUF727 PF05303.7 ETO14301.1 - 0.0075 16.0 1.7 1.8 8.3 0.0 4.2 5 0 0 5 5 5 1 Protein of unknown function (DUF727) DUF1258 PF06869.7 ETO14301.1 - 0.033 13.2 0.5 0.34 9.9 0.2 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1258) AcetylCoA_hyd_C PF13336.1 ETO14301.1 - 0.079 12.6 0.4 2.4 7.7 0.0 3.4 3 2 2 5 5 5 0 Acetyl-CoA hydrolase/transferase C-terminal domain Resistin PF06954.6 ETO14301.1 - 0.19 11.9 5.3 17 5.7 0.0 4.5 2 2 4 6 6 6 0 Resistin Ins_P5_2-kin PF06090.7 ETO14302.1 - 1.9e-30 105.9 9.5 6.6e-30 104.2 6.6 1.8 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Sec20 PF03908.8 ETO14302.1 - 0.086 12.5 2.1 0.25 11.0 1.1 2.0 2 0 0 2 2 2 0 Sec20 G-patch_2 PF12656.2 ETO14303.1 - 0.00068 19.4 0.9 0.00088 19.0 0.1 1.6 2 0 0 2 2 2 1 DExH-box splicing factor binding site G-patch PF01585.18 ETO14303.1 - 0.038 13.7 0.1 0.066 13.0 0.1 1.4 1 0 0 1 1 1 0 G-patch domain CENP-C_mid PF15620.1 ETO14303.1 - 0.045 13.4 3.9 0.047 13.4 2.7 1.1 1 0 0 1 1 1 0 Centromere assembly component CENP-C middle DNMT3B-binding region Med12-LCEWAV PF12145.3 ETO14303.1 - 0.046 12.2 0.3 0.053 12.0 0.2 1.1 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain DUF4606 PF15379.1 ETO14303.1 - 0.19 11.8 2.5 0.3 11.1 1.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4606) S1FA PF04689.8 ETO14305.1 - 0.21 11.5 3.5 14 5.6 0.0 3.0 2 0 0 2 2 2 0 DNA binding protein S1FA Pkinase PF00069.20 ETO14306.1 - 1.6e-40 138.8 0.0 2e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO14306.1 - 1.1e-18 67.3 0.1 1.2e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO14306.1 - 0.00059 18.9 0.0 0.00094 18.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETO14306.1 - 0.019 13.9 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 ETO14306.1 - 0.052 13.2 0.0 0.088 12.5 0.0 1.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family AMP-binding PF00501.23 ETO14308.1 - 7.1e-43 146.5 0.1 9.1e-43 146.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme WD40 PF00400.27 ETO14309.1 - 0.00011 21.8 0.5 0.00034 20.3 0.4 1.8 2 0 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO14309.1 - 0.12 10.4 0.0 0.12 10.4 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 TPR_11 PF13414.1 ETO14310.1 - 2e-10 40.1 8.2 1.1e-08 34.5 1.1 2.7 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETO14310.1 - 3.8e-08 32.5 1.1 0.009 15.5 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO14310.1 - 1.6e-07 31.1 2.0 3.4e-07 30.0 1.0 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO14310.1 - 3.8e-07 30.3 0.0 8.5e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO14310.1 - 1.1e-06 28.0 0.6 0.023 14.4 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO14310.1 - 1.9e-06 27.3 1.0 0.018 14.9 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO14310.1 - 2.4e-06 27.6 0.2 0.00097 19.5 0.1 2.7 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO14310.1 - 1.9e-05 25.1 0.2 0.00021 21.8 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO14310.1 - 0.0011 18.9 1.3 0.0065 16.5 0.9 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 ETO14310.1 - 0.0017 18.4 0.4 0.067 13.4 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.1 ETO14310.1 - 0.0059 16.7 0.1 0.016 15.2 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO14310.1 - 0.012 16.0 0.8 2.3 8.8 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Coatomer_E PF04733.9 ETO14310.1 - 0.022 13.9 0.8 0.27 10.3 0.5 2.2 1 1 1 2 2 2 0 Coatomer epsilon subunit TPR_10 PF13374.1 ETO14310.1 - 0.029 14.2 0.1 10 6.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat SNAP PF14938.1 ETO14310.1 - 0.043 12.9 0.6 0.06 12.4 0.4 1.2 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_21 PF09976.4 ETO14310.1 - 0.081 12.8 0.1 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETO14310.1 - 0.14 12.0 0.5 2 8.4 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat IBR PF01485.16 ETO14312.1 - 0.064 13.1 0.6 0.16 11.9 0.1 1.9 2 0 0 2 2 2 0 IBR domain RAB3GAP2_N PF14655.1 ETO14313.1 - 0.011 14.7 1.5 0.011 14.7 1.1 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Serinc PF03348.10 ETO14313.1 - 0.022 13.5 1.5 0.024 13.3 1.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Spt20 PF12090.3 ETO14313.1 - 0.84 8.9 8.5 0.11 11.7 2.1 1.9 2 0 0 2 2 2 0 Spt20 family Di19_C PF14571.1 ETO14313.1 - 2.7 8.3 11.1 5.1 7.4 0.3 2.8 2 1 1 3 3 3 0 Stress-induced protein Di19, C-terminal DUF912 PF06024.7 ETO14313.1 - 4.7 7.3 6.0 15 5.7 1.6 2.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PH_4 PF15404.1 ETO14313.1 - 8.5 5.8 10.2 1.2 8.6 3.6 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain BTV_NS2 PF04514.7 ETO14314.1 - 0.33 9.7 6.4 0.5 9.2 4.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Macoilin PF09726.4 ETO14315.1 - 1.5 7.0 17.6 1.8 6.7 12.2 1.0 1 0 0 1 1 1 0 Transmembrane protein Ribosomal_S6e PF01092.14 ETO14316.1 - 3.1e-46 156.1 0.4 6.9e-46 155.0 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein S6e Sec7 PF01369.15 ETO14318.1 - 2.4e-54 183.9 3.4 7.2e-54 182.3 2.4 1.9 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 ETO14318.1 - 5.7e-37 126.7 2.2 1.8e-36 125.1 1.5 2.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal zf-XS PF03470.9 ETO14319.1 - 0.13 12.3 3.1 0.53 10.3 2.2 2.1 1 0 0 1 1 1 0 XS zinc finger domain CPSF100_C PF13299.1 ETO14319.1 - 5.3 7.1 9.6 0.36 11.0 0.3 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal zf-C2H2_4 PF13894.1 ETO14320.1 - 0.0011 19.1 0.3 0.0011 19.1 0.2 2.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.21 ETO14320.1 - 0.14 12.5 0.2 0.14 12.5 0.2 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-Di19 PF05605.7 ETO14320.1 - 0.53 10.4 0.1 0.53 10.4 0.1 2.3 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding RasGAP PF00616.14 ETO14321.1 - 0.23 11.1 2.6 0.24 11.0 1.3 1.3 1 1 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase DUF1840 PF08895.6 ETO14322.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) DUF3336 PF11815.3 ETO14324.1 - 2.1e-09 37.0 0.8 3.2e-09 36.4 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Cut8_C PF08559.5 ETO14324.1 - 0.0046 16.8 0.1 2.3 8.0 0.0 2.4 2 0 0 2 2 2 2 Cut8 six-helix bundle ER PF01133.12 ETO14324.1 - 0.06 13.0 0.1 0.16 11.7 0.1 1.7 2 0 0 2 2 2 0 Enhancer of rudimentary RVT_thumb PF06817.9 ETO14324.1 - 0.093 12.3 0.5 0.45 10.1 0.2 2.2 2 1 1 3 3 3 0 Reverse transcriptase thumb domain Patatin PF01734.17 ETO14325.1 - 2.1e-22 80.0 0.0 3.3e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase DUF3336 PF11815.3 ETO14325.1 - 2.2e-15 56.4 0.1 5.9e-15 55.0 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) SNAPc19 PF15497.1 ETO14325.1 - 0.00072 19.7 0.2 0.0016 18.6 0.1 1.5 1 0 0 1 1 1 1 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Myc_N PF01056.13 ETO14326.1 - 0.067 12.3 0.9 0.078 12.1 0.7 1.1 1 0 0 1 1 1 0 Myc amino-terminal region SR-25 PF10500.4 ETO14327.1 - 0.021 14.3 4.8 0.036 13.5 3.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Orbi_NS3 PF01616.11 ETO14327.1 - 0.021 13.7 0.9 0.034 13.1 0.6 1.3 1 0 0 1 1 1 0 Orbivirus NS3 COG2 PF06148.6 ETO14327.1 - 0.042 13.7 3.0 0.17 11.7 0.4 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1117 PF06547.7 ETO14327.1 - 0.19 11.8 1.4 0.35 10.9 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) D5_N PF08706.6 ETO14327.1 - 0.83 9.7 3.5 21 5.1 1.7 2.1 1 1 1 2 2 2 0 D5 N terminal like YgaB PF14182.1 ETO14327.1 - 7.1 6.9 13.7 0.3 11.3 0.4 2.9 1 1 1 2 2 2 0 YgaB-like protein D123 PF07065.9 ETO14328.1 - 2.7e-18 66.0 0.4 2.7e-18 66.0 0.3 2.4 2 0 0 2 2 2 2 D123 DUF4343 PF14243.1 ETO14328.1 - 4.3e-05 23.3 0.0 9.4e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4343) Pex14_N PF04695.8 ETO14332.1 - 0.0082 16.1 12.2 0.012 15.7 8.5 1.4 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.8 ETO14332.1 - 0.011 15.6 16.6 0.012 15.5 11.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SprA-related PF12118.3 ETO14332.1 - 0.014 14.7 19.7 0.016 14.5 13.6 1.1 1 0 0 1 1 1 0 SprA-related family DUF1764 PF08576.5 ETO14332.1 - 0.044 14.5 9.1 0.077 13.7 6.3 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) eIF-3_zeta PF05091.7 ETO14332.1 - 0.05 12.2 14.4 0.053 12.1 10.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) APG6 PF04111.7 ETO14332.1 - 0.07 12.1 14.4 0.079 11.9 10.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Ctr PF04145.10 ETO14332.1 - 0.081 12.9 6.4 0.12 12.4 4.4 1.3 1 0 0 1 1 1 0 Ctr copper transporter family PAT1 PF09770.4 ETO14332.1 - 0.083 11.1 24.6 0.091 10.9 17.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_23 PF13476.1 ETO14332.1 - 0.1 12.9 12.4 0.13 12.5 8.6 1.1 1 0 0 1 1 1 0 AAA domain Pex26 PF07163.7 ETO14332.1 - 0.25 10.2 7.6 0.31 9.9 5.3 1.1 1 0 0 1 1 1 0 Pex26 protein CPSF100_C PF13299.1 ETO14332.1 - 0.28 11.3 7.2 0.34 11.0 5.0 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4557 PF15101.1 ETO14332.1 - 0.28 11.0 17.8 0.35 10.6 12.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Neur_chan_memb PF02932.11 ETO14332.1 - 0.31 10.9 3.8 0.31 10.8 2.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region OmpH PF03938.9 ETO14332.1 - 0.34 10.8 23.3 0.41 10.5 16.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FHIPEP PF00771.15 ETO14332.1 - 0.34 9.1 5.1 0.38 9.0 3.5 1.1 1 0 0 1 1 1 0 FHIPEP family MDFI PF15316.1 ETO14332.1 - 0.42 10.6 5.2 0.53 10.2 3.6 1.2 1 0 0 1 1 1 0 MyoD family inhibitor Phage_GPO PF05929.6 ETO14332.1 - 0.5 9.5 9.9 0.6 9.3 6.8 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Serinc PF03348.10 ETO14332.1 - 0.55 8.8 10.2 0.67 8.6 7.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF605 PF04652.11 ETO14332.1 - 0.59 9.4 18.3 0.71 9.2 12.7 1.1 1 0 0 1 1 1 0 Vta1 like DUF4407 PF14362.1 ETO14332.1 - 0.63 8.9 12.2 0.84 8.5 8.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Kei1 PF08552.6 ETO14332.1 - 0.74 9.4 6.7 0.96 9.0 4.6 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 EIIBC-GUT_N PF03612.9 ETO14332.1 - 1.2 8.7 8.3 5 6.7 6.4 1.6 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Band_3_cyto PF07565.8 ETO14332.1 - 1.3 8.5 13.6 1.7 8.1 9.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF853 PF05872.7 ETO14332.1 - 1.5 7.1 7.5 1.7 6.9 5.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF3533 PF12051.3 ETO14332.1 - 1.5 7.4 10.2 2 7.0 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) CRF1 PF10380.4 ETO14332.1 - 1.6 9.0 5.7 2.1 8.6 4.0 1.3 1 0 0 1 1 1 0 Transcription factor CRF1 Zip PF02535.17 ETO14332.1 - 2.3 7.1 5.4 2.4 7.0 3.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter FAM176 PF14851.1 ETO14332.1 - 2.3 7.8 8.0 3.8 7.1 5.5 1.3 1 0 0 1 1 1 0 FAM176 family RED_N PF07808.8 ETO14332.1 - 2.9 7.0 19.9 4.9 6.2 13.8 1.3 1 0 0 1 1 1 0 RED-like protein N-terminal region F-protein PF00469.15 ETO14332.1 - 3.6 6.8 12.4 5.1 6.4 8.6 1.2 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Paramyxo_ncap PF00973.14 ETO14332.1 - 3.8 6.0 7.2 4.4 5.8 5.0 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Peptidase_S49_N PF08496.5 ETO14332.1 - 4.2 7.1 10.9 6.2 6.5 7.6 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal AIF_C PF14721.1 ETO14332.1 - 4.8 7.4 9.9 7.6 6.7 6.9 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term G0-G1_switch_2 PF15103.1 ETO14332.1 - 4.9 7.4 7.9 7.7 6.8 5.5 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 Folate_carrier PF01770.13 ETO14332.1 - 5.6 5.3 8.6 7.8 4.8 6.0 1.2 1 0 0 1 1 1 0 Reduced folate carrier ATAD4 PF15321.1 ETO14332.1 - 5.9 7.9 11.8 12 6.9 8.2 1.5 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 DUF3371 PF11851.3 ETO14332.1 - 6 7.5 17.2 9.6 6.9 11.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) DUF4175 PF13779.1 ETO14332.1 - 6.1 4.4 34.4 7.6 4.0 23.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) UPF0560 PF10577.4 ETO14332.1 - 9 4.4 17.5 11 4.0 12.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 PTCB-BRCT PF12738.2 ETO14333.1 - 1.8e-09 37.2 2.4 2.8e-09 36.6 0.2 2.1 2 1 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 ETO14333.1 - 1.9e-08 34.3 0.2 4.3e-08 33.2 0.0 1.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DUF2851 PF11013.3 ETO14333.1 - 0.062 12.0 0.0 0.069 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2851) BBIP10 PF14777.1 ETO14333.1 - 0.13 11.6 0.7 0.23 10.8 0.5 1.3 1 0 0 1 1 1 0 Cilia BBSome complex subunit 10 THAP PF05485.7 ETO14333.1 - 1.9 8.7 4.9 15 5.8 0.4 2.3 2 1 0 2 2 2 0 THAP domain NIF PF03031.13 ETO14334.1 - 1.2e-16 60.7 0.1 1.9e-16 60.1 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase TPR_12 PF13424.1 ETO14335.1 - 4.3e-35 119.5 5.9 3.9e-13 49.1 0.1 4.4 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO14335.1 - 1e-19 69.1 25.3 2.3e-05 23.7 0.4 5.7 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETO14335.1 - 4.1e-18 64.6 0.0 7.4e-05 22.5 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO14335.1 - 6.4e-18 64.1 23.1 1.3e-07 31.1 0.6 4.4 2 2 2 4 4 4 4 TPR repeat TPR_8 PF13181.1 ETO14335.1 - 2.3e-16 58.2 27.0 0.00026 20.5 0.2 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO14335.1 - 2e-15 55.3 18.3 0.001 18.8 0.2 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO14335.1 - 1.3e-14 52.7 1.7 0.07 12.9 0.0 5.9 5 0 0 5 5 5 4 Tetratricopeptide repeat Apc3 PF12895.2 ETO14335.1 - 1.8e-05 24.7 9.7 4.3e-05 23.5 2.0 3.0 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 ETO14335.1 - 0.0016 17.6 0.0 0.42 9.9 0.0 3.6 3 0 0 3 3 3 1 SHNi-TPR MIT PF04212.13 ETO14335.1 - 0.0024 17.7 12.2 1 9.2 0.2 5.3 5 0 0 5 5 5 2 MIT (microtubule interacting and transport) domain DUF2225 PF09986.4 ETO14335.1 - 0.0026 17.2 2.6 0.0026 17.2 1.8 2.6 1 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_6 PF13174.1 ETO14335.1 - 0.0055 17.0 6.5 3.3 8.3 0.0 4.4 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_3 PF07720.7 ETO14335.1 - 0.016 15.0 0.2 0.016 15.0 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETO14335.1 - 0.068 13.8 0.0 3.9 8.2 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETO14335.1 - 0.16 12.6 0.0 94 4.0 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Kelch_2 PF07646.10 ETO14335.1 - 0.21 11.4 1.3 6.9 6.6 0.1 2.5 2 0 0 2 2 2 0 Kelch motif YtzH PF14165.1 ETO14335.1 - 0.89 9.8 8.6 0.42 10.8 0.1 3.7 3 1 0 3 3 3 0 YtzH-like protein TPR_17 PF13431.1 ETO14335.1 - 1 9.7 6.8 2.1 8.7 0.1 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.27 ETO14336.1 - 5.8e-88 285.9 16.9 2e-14 52.7 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO14336.1 - 4.2e-08 31.9 1.9 0.0016 16.8 0.1 3.0 1 1 2 3 3 3 3 Cytochrome D1 heme domain Nup160 PF11715.3 ETO14336.1 - 5.2e-08 31.4 10.6 0.45 8.5 0.0 5.8 1 1 5 6 6 6 5 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO14336.1 - 3.3e-07 30.0 2.9 0.00033 20.2 0.2 3.3 2 1 1 3 3 3 1 PQQ-like domain SGL PF08450.7 ETO14336.1 - 5.9e-06 25.8 3.0 0.0025 17.2 0.2 1.9 1 1 1 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Nucleoporin_N PF08801.6 ETO14336.1 - 4e-05 22.5 15.0 0.25 10.0 0.1 5.9 2 1 4 7 7 7 2 Nup133 N terminal like DUF1513 PF07433.6 ETO14336.1 - 0.00013 20.9 0.1 0.099 11.5 0.0 3.0 1 1 3 4 4 4 2 Protein of unknown function (DUF1513) RicinB_lectin_2 PF14200.1 ETO14336.1 - 0.0061 16.9 1.6 0.16 12.3 0.0 3.3 3 1 0 3 3 3 1 Ricin-type beta-trefoil lectin domain-like Hira PF07569.6 ETO14336.1 - 0.0062 15.7 1.1 9.7 5.3 0.0 4.3 2 1 4 6 6 6 1 TUP1-like enhancer of split PD40 PF07676.7 ETO14336.1 - 0.021 14.4 4.2 35 4.1 0.0 5.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat PLD_C PF12357.3 ETO14336.1 - 0.046 13.2 0.6 25 4.5 0.0 3.9 4 1 1 5 5 5 0 Phospholipase D C terminal Proteasome_A_N PF10584.4 ETO14336.1 - 0.054 12.8 0.1 8.6 5.7 0.0 3.3 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature B_lectin PF01453.19 ETO14336.1 - 0.065 13.1 6.5 0.075 12.9 0.1 3.1 2 1 1 3 3 3 0 D-mannose binding lectin Asp_decarbox PF02261.11 ETO14336.1 - 0.12 12.0 0.0 0.41 10.2 0.0 2.0 2 0 0 2 2 2 0 Aspartate decarboxylase DUF1258 PF06869.7 ETO14336.1 - 0.13 11.3 2.7 0.8 8.7 0.0 3.3 2 1 2 5 5 5 0 Protein of unknown function (DUF1258) WD40 PF00400.27 ETO14337.1 - 4.1e-59 194.4 25.8 6.5e-13 48.0 0.0 7.7 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO14337.1 - 2.2e-12 45.8 9.0 0.0019 16.4 0.8 5.7 1 1 5 6 6 6 5 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO14337.1 - 0.015 14.7 0.1 0.2 11.1 0.0 2.7 2 1 0 2 2 2 0 PQQ-like domain DUF3601 PF12208.3 ETO14337.1 - 5.3 7.0 9.3 8.9 6.3 0.0 5.0 4 2 2 6 6 6 0 Domain of unknown function (DUF3601) G-gamma PF00631.17 ETO14338.1 - 0.0015 18.2 0.1 0.0029 17.3 0.1 1.5 1 0 0 1 1 1 1 GGL domain Dicty_REP PF05086.7 ETO14340.1 - 0.019 12.7 10.4 0.0027 15.5 4.6 1.5 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein DUF4261 PF14080.1 ETO14340.1 - 0.029 14.1 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4261) Mucin PF01456.12 ETO14340.1 - 0.031 14.0 25.0 0.048 13.4 17.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.6 ETO14340.1 - 5.5 4.8 22.6 8.4 4.2 15.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF1160 PF06648.6 ETO14344.1 - 0.071 12.9 0.3 0.12 12.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) DUF349 PF03993.7 ETO14344.1 - 0.68 10.1 6.7 0.21 11.7 1.9 2.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) N6_N4_Mtase PF01555.13 ETO14346.1 - 0.0025 17.3 2.2 0.0033 16.9 1.5 1.1 1 0 0 1 1 1 1 DNA methylase MKT1_C PF12246.3 ETO14346.1 - 0.071 12.0 0.6 0.093 11.7 0.4 1.2 1 0 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication DUF2992 PF11208.3 ETO14347.1 - 0.0095 15.8 1.3 0.016 15.1 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2992) SET PF00856.23 ETO14347.1 - 0.01 16.1 0.1 0.041 14.1 0.0 1.9 2 0 0 2 2 2 0 SET domain PEPCK PF00821.13 ETO14348.1 - 9.1e-33 113.2 3.2 1.7e-31 109.0 2.2 1.9 1 1 0 1 1 1 1 Phosphoenolpyruvate carboxykinase GTP_EFTU PF00009.22 ETO14349.1 - 3e-21 75.7 0.1 3e-21 75.7 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 ETO14349.1 - 7e-14 51.8 0.0 2e-13 50.3 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 ETO14349.1 - 0.00014 21.7 1.7 0.00026 20.9 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 ETO14349.1 - 0.0018 18.3 0.1 0.011 15.8 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 G-alpha PF00503.15 ETO14349.1 - 0.0042 15.8 0.4 0.0042 15.8 0.3 2.4 2 1 0 2 2 2 1 G-protein alpha subunit Miro PF08477.8 ETO14349.1 - 0.015 15.8 0.5 0.084 13.3 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein MobB PF03205.9 ETO14349.1 - 0.032 13.9 0.6 0.48 10.1 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Pheromone PF08015.6 ETO14349.1 - 3.3 8.6 10.0 17 6.3 6.9 2.3 1 1 0 1 1 1 0 Fungal mating-type pheromone PPR_2 PF13041.1 ETO14351.1 - 0.00013 21.8 0.2 0.4 10.6 0.0 3.6 3 1 1 4 4 4 3 PPR repeat family PPR_3 PF13812.1 ETO14351.1 - 0.0053 16.9 0.1 30 5.2 0.0 4.9 6 0 0 6 6 6 1 Pentatricopeptide repeat domain Kinesin-relat_1 PF12711.2 ETO14352.1 - 0.021 15.2 11.4 0.021 15.2 7.9 4.6 2 1 3 5 5 5 0 Kinesin motor DUF869 PF05911.6 ETO14352.1 - 0.14 10.3 43.4 0.2 9.8 30.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) DASH_Dam1 PF08653.5 ETO14352.1 - 0.4 10.4 14.1 0.083 12.6 2.0 3.5 2 1 1 3 3 3 0 DASH complex subunit Dam1 FliD_N PF02465.13 ETO14352.1 - 0.57 10.5 22.4 0.12 12.7 1.9 4.0 3 1 1 4 4 4 0 Flagellar hook-associated protein 2 N-terminus Reo_sigmaC PF04582.7 ETO14352.1 - 1.3 8.1 6.2 1.7 7.7 0.2 2.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein PilJ PF13675.1 ETO14352.1 - 2 8.7 18.3 2.2 8.6 1.3 3.1 1 1 4 5 5 5 0 Type IV pili methyl-accepting chemotaxis transducer N-term Pyr_redox PF00070.22 ETO14352.1 - 2.1 8.8 5.0 2.4 8.6 1.5 2.4 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase IncA PF04156.9 ETO14352.1 - 2.4 7.7 52.9 0.17 11.4 15.4 2.9 2 2 0 2 2 2 0 IncA protein RseA_C PF03873.8 ETO14352.1 - 7.9 6.4 17.9 0.24 11.3 0.9 4.0 3 0 0 3 3 3 0 Anti sigma-E protein RseA, C-terminal domain Clat_adaptor_s PF01217.15 ETO14353.1 - 0.028 14.1 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Clathrin adaptor complex small chain EF-hand_7 PF13499.1 ETO14354.1 - 2e-12 47.0 1.0 2.8e-12 46.6 0.7 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO14354.1 - 1.8e-10 39.3 3.3 0.00015 20.8 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 ETO14354.1 - 3e-09 35.9 0.5 0.0006 19.4 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 ETO14354.1 - 4.7e-08 32.0 5.6 0.00056 19.1 0.3 2.6 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 ETO14354.1 - 5.6e-06 25.8 2.9 1.8e-05 24.2 1.5 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.1 ETO14354.1 - 0.032 14.1 0.1 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain SPARC_Ca_bdg PF10591.4 ETO14354.1 - 0.057 13.4 0.1 0.088 12.8 0.0 1.3 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 ETO14354.1 - 0.15 11.8 0.8 0.29 10.8 0.6 1.6 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand DUF563 PF04577.9 ETO14355.1 - 5.6e-07 29.6 0.9 1.9e-06 27.9 0.3 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF563) Cyclin_N PF00134.18 ETO14356.1 - 1.1e-11 44.4 7.0 1.8e-05 24.2 0.8 3.9 2 1 1 3 3 3 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 ETO14356.1 - 0.00012 21.9 0.9 0.00012 21.9 0.6 3.1 3 1 0 3 3 3 1 Cyclin, C-terminal domain DUF1632 PF07857.7 ETO14357.1 - 8.9e-48 162.7 0.6 1.5e-47 161.9 0.4 1.3 1 0 0 1 1 1 1 CEO family (DUF1632) Sugar_transport PF06800.7 ETO14357.1 - 4.3e-05 22.7 3.0 7.1e-05 22.0 2.1 1.3 1 0 0 1 1 1 1 Sugar transport protein FAM176 PF14851.1 ETO14357.1 - 0.02 14.5 0.1 0.02 14.5 0.1 1.8 3 0 0 3 3 3 0 FAM176 family Nucleoplasmin PF03066.10 ETO14357.1 - 0.88 9.0 8.2 1.5 8.3 5.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 ETO14357.1 - 1.5 9.1 11.5 2.8 8.2 8.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Kelch_6 PF13964.1 ETO14358.1 - 8.4e-09 35.2 0.2 1.8e-06 27.8 0.0 3.6 2 1 1 3 3 3 1 Kelch motif Kelch_1 PF01344.20 ETO14358.1 - 7.9e-08 31.7 0.2 1e-06 28.1 0.0 3.0 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 ETO14358.1 - 1.1e-07 31.7 0.0 1.8e-06 27.9 0.0 2.8 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO14358.1 - 1.9e-05 24.3 0.2 0.0003 20.4 0.0 3.0 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO14358.1 - 0.028 14.2 3.8 0.034 13.9 0.0 3.2 4 1 0 4 4 4 0 Kelch motif Kelch_5 PF13854.1 ETO14358.1 - 0.2 11.6 1.6 2 8.4 0.0 3.3 3 0 0 3 3 3 0 Kelch motif Nepo_coat_N PF03689.10 ETO14359.1 - 0.013 15.2 0.6 2.8 7.7 0.1 2.2 2 0 0 2 2 2 0 Nepovirus coat protein, N-terminal domain SAM_2 PF07647.12 ETO14360.1 - 4.7e-10 39.1 0.0 1.3e-05 24.9 0.0 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) Dynamin_N PF00350.18 ETO14360.1 - 4.4e-07 29.8 0.9 1.3e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 Dynamin family SAM_1 PF00536.25 ETO14360.1 - 0.00055 20.0 0.1 0.002 18.2 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Miro PF08477.8 ETO14360.1 - 0.0012 19.3 0.0 0.0048 17.3 0.0 2.1 1 0 0 1 1 1 1 Miro-like protein SAM_PNT PF02198.11 ETO14360.1 - 0.07 12.8 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain AAA_28 PF13521.1 ETO14360.1 - 0.083 12.8 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain KxDL PF10241.4 ETO14361.1 - 0.0077 16.1 6.1 0.0077 16.1 4.2 4.3 4 1 1 5 5 5 1 Uncharacterized conserved protein Myosin_tail_1 PF01576.14 ETO14362.1 - 0.0015 16.3 13.2 0.0016 16.3 9.2 1.0 1 0 0 1 1 1 1 Myosin tail MAD PF05557.8 ETO14362.1 - 0.016 13.3 11.9 0.018 13.1 8.3 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein FliJ PF02050.11 ETO14362.1 - 0.024 14.6 8.5 0.028 14.4 5.9 1.0 1 0 0 1 1 1 0 Flagellar FliJ protein Chordopox_L2 PF05803.7 ETO14362.1 - 0.028 14.0 1.0 0.047 13.3 0.3 1.7 1 1 1 2 2 2 0 Chordopoxvirus L2 protein CALCOCO1 PF07888.6 ETO14362.1 - 0.065 11.5 9.7 0.068 11.4 6.7 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Pox_A_type_inc PF04508.7 ETO14362.1 - 0.067 12.9 7.2 0.78 9.6 0.6 3.2 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat Tropomyosin PF00261.15 ETO14362.1 - 0.073 12.1 13.6 0.084 11.9 9.4 1.0 1 0 0 1 1 1 0 Tropomyosin Sugarporin_N PF11471.3 ETO14362.1 - 0.073 12.7 1.3 0.073 12.7 0.9 2.4 1 1 1 2 2 1 0 Maltoporin periplasmic N-terminal extension DUF948 PF06103.6 ETO14362.1 - 0.076 12.8 3.7 0.091 12.6 2.6 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) SRP14 PF02290.10 ETO14362.1 - 0.081 12.8 2.0 0.089 12.7 1.4 1.2 1 0 0 1 1 1 0 Signal recognition particle 14kD protein TACC PF05010.9 ETO14362.1 - 0.096 12.4 9.9 0.12 12.1 6.8 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) DUF2067 PF09840.4 ETO14362.1 - 0.099 12.1 3.6 0.11 12.0 2.5 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) Cep57_MT_bd PF06657.8 ETO14362.1 - 0.1 12.5 5.3 0.13 12.2 3.7 1.2 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 GAS PF13851.1 ETO14362.1 - 0.11 11.6 14.9 0.19 10.8 10.3 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF342 PF03961.8 ETO14362.1 - 0.11 10.8 12.9 0.13 10.6 9.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DMPK_coil PF08826.5 ETO14362.1 - 0.11 12.3 8.2 0.28 11.1 4.4 2.2 1 1 1 2 2 2 0 DMPK coiled coil domain like APG6 PF04111.7 ETO14362.1 - 0.11 11.4 14.1 0.12 11.3 9.8 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2802 PF10975.3 ETO14362.1 - 0.12 12.1 6.1 6.2 6.6 4.2 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2802) Transposase_22 PF02994.9 ETO14362.1 - 0.13 10.7 9.7 0.14 10.6 6.7 1.0 1 0 0 1 1 1 0 L1 transposable element Fib_alpha PF08702.5 ETO14362.1 - 0.14 12.3 10.0 0.69 10.0 6.9 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Fmp27_WPPW PF10359.4 ETO14362.1 - 0.14 10.5 9.1 0.14 10.5 6.3 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain CENP-F_leu_zip PF10473.4 ETO14362.1 - 0.16 11.8 15.0 1.3 8.9 10.4 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YPEB PF14620.1 ETO14362.1 - 0.16 10.9 4.5 0.18 10.7 3.1 1.0 1 0 0 1 1 1 0 YpeB sporulation V_ATPase_I PF01496.14 ETO14362.1 - 0.2 9.5 10.3 0.2 9.4 7.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIVA PF05103.8 ETO14362.1 - 0.22 11.5 12.3 0.3 11.1 8.5 1.3 1 1 0 1 1 1 0 DivIVA protein Nup54 PF13874.1 ETO14362.1 - 0.26 10.9 8.7 0.3 10.7 6.0 1.1 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 CD34_antigen PF06365.7 ETO14362.1 - 0.29 10.7 8.6 0.34 10.5 5.9 1.0 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF812 PF05667.6 ETO14362.1 - 0.33 9.3 11.7 0.34 9.3 8.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF3584 PF12128.3 ETO14362.1 - 0.35 8.1 11.5 0.36 8.1 8.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Seryl_tRNA_N PF02403.17 ETO14362.1 - 0.35 10.8 12.2 0.61 10.1 8.5 1.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TBPIP PF07106.8 ETO14362.1 - 0.46 10.0 13.5 0.53 9.8 9.3 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mnd1 PF03962.10 ETO14362.1 - 0.48 10.0 13.1 0.54 9.8 9.1 1.0 1 0 0 1 1 1 0 Mnd1 family Oxysterol_BP PF01237.13 ETO14362.1 - 0.5 8.7 5.7 0.52 8.7 3.9 1.0 1 0 0 1 1 1 0 Oxysterol-binding protein YkyA PF10368.4 ETO14362.1 - 0.53 9.5 13.0 0.62 9.3 9.0 1.1 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein CENP-H PF05837.7 ETO14362.1 - 0.59 10.3 11.5 0.77 9.9 8.0 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF3552 PF12072.3 ETO14362.1 - 0.59 9.3 14.3 0.78 8.9 9.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) PspA_IM30 PF04012.7 ETO14362.1 - 0.65 9.3 10.2 0.14 11.4 3.5 1.8 1 1 1 2 2 2 0 PspA/IM30 family Syntaxin PF00804.20 ETO14362.1 - 0.76 9.9 11.4 0.9 9.7 7.9 1.1 1 0 0 1 1 1 0 Syntaxin Prefoldin PF02996.12 ETO14362.1 - 0.96 9.1 11.0 0.059 13.0 2.4 2.0 1 1 1 2 2 2 0 Prefoldin subunit DUF1664 PF07889.7 ETO14362.1 - 1 9.1 6.8 1.1 9.0 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) IncA PF04156.9 ETO14362.1 - 1 8.8 13.5 1.3 8.5 9.4 1.1 1 0 0 1 1 1 0 IncA protein Ax_dynein_light PF10211.4 ETO14362.1 - 1.2 8.8 14.9 3.3 7.5 10.3 1.6 1 1 0 1 1 1 0 Axonemal dynein light chain Uds1 PF15456.1 ETO14362.1 - 1.3 9.0 9.1 1.6 8.7 6.3 1.1 1 0 0 1 1 1 0 Up-regulated During Septation Cortex-I_coil PF09304.5 ETO14362.1 - 1.6 8.7 12.2 4.2 7.4 8.4 1.7 1 1 0 1 1 1 0 Cortexillin I, coiled coil DivIC PF04977.10 ETO14362.1 - 1.7 8.1 14.4 0.41 10.1 1.2 2.2 1 1 1 2 2 2 0 Septum formation initiator Prefoldin_2 PF01920.15 ETO14362.1 - 1.8 8.4 16.3 0.053 13.2 2.3 2.3 1 1 1 2 2 2 0 Prefoldin subunit DUF641 PF04859.7 ETO14362.1 - 1.8 8.3 9.9 3.1 7.5 3.7 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Spc24 PF08286.6 ETO14362.1 - 1.9 8.1 15.1 0.42 10.3 5.9 1.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 FlaC_arch PF05377.6 ETO14362.1 - 2.2 8.2 10.5 2 8.3 2.9 2.8 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) FemAB PF02388.11 ETO14362.1 - 2.6 6.6 9.9 2.6 6.6 6.8 1.1 1 0 0 1 1 1 0 FemAB family TMPIT PF07851.8 ETO14362.1 - 2.9 6.8 10.8 3.3 6.6 7.5 1.0 1 0 0 1 1 1 0 TMPIT-like protein TMF_DNA_bd PF12329.3 ETO14362.1 - 3.1 7.6 17.4 5.4 6.9 1.6 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4200 PF13863.1 ETO14362.1 - 3.1 7.7 16.1 5.3 7.0 11.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DASH_Spc34 PF08657.5 ETO14362.1 - 3.4 7.2 12.5 4.2 6.9 8.7 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 Macoilin PF09726.4 ETO14362.1 - 6 5.0 11.7 6 5.0 8.1 1.0 1 0 0 1 1 1 0 Transmembrane protein bZIP_1 PF00170.16 ETO14362.1 - 7.4 6.6 12.2 16 5.5 1.8 2.4 1 1 1 2 2 2 0 bZIP transcription factor DUF3450 PF11932.3 ETO14362.1 - 8.2 5.6 9.9 11 5.1 6.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) YtxH PF12732.2 ETO14362.1 - 9.1 6.7 7.5 21 5.5 4.9 1.8 1 1 0 1 1 1 0 YtxH-like protein DUF972 PF06156.8 ETO14362.1 - 9.8 6.5 11.4 16 5.8 7.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Miro PF08477.8 ETO14363.1 - 0.00017 22.1 1.4 0.0083 16.6 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 ETO14363.1 - 0.0043 16.9 0.3 0.037 13.9 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 ETO14363.1 - 0.012 15.3 5.5 0.3 10.8 0.4 2.1 2 0 0 2 2 2 0 Dynamin family Tim54 PF11711.3 ETO14363.1 - 0.04 12.5 1.1 0.046 12.3 0.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 tRNA-Thr_ED PF08915.6 ETO14363.1 - 0.047 13.6 0.3 0.067 13.1 0.2 1.2 1 0 0 1 1 1 0 Archaea-specific editing domain of threonyl-tRNA synthetase DUF2413 PF10310.4 ETO14363.1 - 0.051 12.3 4.9 0.065 12.0 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) TRAP_alpha PF03896.11 ETO14363.1 - 0.14 11.0 2.5 0.19 10.6 1.7 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit YqfQ PF14181.1 ETO14363.1 - 4.1 7.4 8.4 5.9 6.8 5.8 1.1 1 0 0 1 1 1 0 YqfQ-like protein RR_TM4-6 PF06459.7 ETO14363.1 - 4.2 7.1 10.8 4.9 6.9 5.1 1.9 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Daxx PF03344.10 ETO14363.1 - 8 4.8 11.8 10 4.4 8.2 1.0 1 0 0 1 1 1 0 Daxx Family RNA_pol_Rpc82 PF05645.8 ETO14365.1 - 0.045 13.2 0.2 0.05 13.1 0.2 1.2 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 TctA PF01970.11 ETO14366.1 - 0.13 10.6 4.2 0.037 12.4 0.3 1.9 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctA family Abhydrolase_9_N PF15420.1 ETO14366.1 - 1.6 8.4 7.1 0.1 12.3 1.4 1.6 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Scs3p PF10261.4 ETO14366.1 - 1.7 7.6 16.8 0.66 8.9 2.7 3.2 2 1 1 3 3 3 0 Inositol phospholipid synthesis and fat-storage-inducing TM Actin PF00022.14 ETO14367.1 - 1.7e-21 76.0 0.2 1.2e-20 73.2 0.1 1.9 1 1 0 1 1 1 1 Actin CENP-B_dimeris PF09026.5 ETO14367.1 - 0.58 10.4 7.7 1.9 8.7 5.5 1.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 ETO14367.1 - 0.65 9.5 6.0 0.9 9.0 3.3 1.8 2 0 0 2 2 2 0 Nucleoplasmin Aminotran_1_2 PF00155.16 ETO14368.1 - 6.1e-10 38.5 0.0 8.2e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3429 PF11911.3 ETO14369.1 - 0.066 13.1 0.7 0.11 12.4 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3429) zf-C3HC4_3 PF13920.1 ETO14370.1 - 6.7e-11 41.6 11.0 1.3e-10 40.8 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO14370.1 - 1.9e-05 24.5 13.9 4.2e-05 23.4 9.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Tudor-knot PF11717.3 ETO14370.1 - 0.00017 21.2 1.5 0.00048 19.7 1.0 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-RING_2 PF13639.1 ETO14370.1 - 0.0073 16.1 15.1 0.025 14.3 10.5 2.0 1 1 0 1 1 1 1 Ring finger domain Rotamase_2 PF13145.1 ETO14370.1 - 0.21 12.2 5.1 2 9.0 0.7 2.4 2 0 0 2 2 2 0 PPIC-type PPIASE domain DUF2457 PF10446.4 ETO14370.1 - 0.22 10.2 32.6 0.29 9.8 11.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) zf-RING_6 PF14835.1 ETO14370.1 - 1.3 8.9 8.8 3.6 7.4 6.1 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein SAM_2 PF07647.12 ETO14370.1 - 1.6 8.5 6.7 1.1 9.2 0.2 3.4 4 0 0 4 4 3 0 SAM domain (Sterile alpha motif) DUF1272 PF06906.6 ETO14370.1 - 1.7 8.5 9.7 5.8 6.8 6.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) FAM176 PF14851.1 ETO14370.1 - 3 7.5 11.3 3.8 7.1 2.2 2.7 2 0 0 2 2 2 0 FAM176 family TRAP_alpha PF03896.11 ETO14370.1 - 3.3 6.6 15.3 0.18 10.7 2.6 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit WD40 PF00400.27 ETO14371.1 - 3e-83 271.0 15.2 3.6e-13 48.8 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO14371.1 - 7.5e-08 30.9 6.3 0.11 10.6 0.1 5.4 1 1 2 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO14371.1 - 1.5e-06 26.7 1.1 0.013 13.8 0.0 3.5 1 1 3 4 4 4 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO14371.1 - 1.9e-06 27.5 0.9 0.00052 19.5 0.1 2.9 1 1 1 3 3 3 1 PQQ-like domain PD40 PF07676.7 ETO14371.1 - 3.8e-06 26.4 4.5 2.4 7.8 0.0 5.9 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO14371.1 - 4.9e-06 25.5 4.8 1.1 7.8 0.3 4.6 1 1 3 4 4 4 3 Nup133 N terminal like Nbas_N PF15492.1 ETO14371.1 - 3.4e-05 23.0 1.2 1.2 8.1 0.0 4.4 2 2 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PQQ PF01011.16 ETO14371.1 - 0.00024 20.5 0.3 2.1 8.0 0.0 4.7 4 1 0 4 4 4 1 PQQ enzyme repeat DHFR_2 PF06442.6 ETO14371.1 - 0.0027 17.2 0.0 2.1 8.0 0.0 3.9 4 1 1 5 5 5 1 R67 dihydrofolate reductase Resistin PF06954.6 ETO14371.1 - 0.003 17.8 0.2 10 6.4 0.0 3.9 3 2 2 5 5 5 1 Resistin DUF727 PF05303.7 ETO14371.1 - 0.0055 16.4 0.0 3.7 7.3 0.0 3.5 3 1 1 4 4 4 1 Protein of unknown function (DUF727) Hira PF07569.6 ETO14371.1 - 0.13 11.5 0.2 25 3.9 0.0 4.0 1 1 2 5 5 5 0 TUP1-like enhancer of split Proteasome_A_N PF10584.4 ETO14371.1 - 8.8 5.7 11.8 39 3.6 0.0 4.9 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Ras PF00071.17 ETO14372.1 - 6.6e-25 87.3 0.1 7e-20 71.0 0.0 2.3 1 1 1 2 2 2 2 Ras family Miro PF08477.8 ETO14372.1 - 0.00032 21.1 0.1 0.00083 19.8 0.1 1.7 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO14372.1 - 0.0041 16.3 0.4 0.035 13.3 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family ABC2_membrane_2 PF12679.2 ETO14373.1 - 0.22 10.3 9.0 0.26 10.0 6.2 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF656 PF04920.7 ETO14373.1 - 1.8 8.2 7.1 4.5 6.9 4.2 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF656) YwiC PF14256.1 ETO14373.1 - 9.4 6.3 13.4 1.2 9.2 5.9 1.9 1 1 1 2 2 2 0 YwiC-like protein Shisa PF13908.1 ETO14373.1 - 9.7 6.3 5.9 16 5.6 4.1 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator WD40 PF00400.27 ETO14374.1 - 4.3e-77 251.4 9.5 5.7e-14 51.3 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO14374.1 - 1.9e-09 36.2 4.3 0.058 11.5 0.0 5.6 2 1 4 6 6 6 3 Nucleoporin Nup120/160 PD40 PF07676.7 ETO14374.1 - 5.5e-08 32.3 5.0 1.7 8.3 0.0 6.2 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO14374.1 - 1.3e-07 31.3 0.7 1.5e-05 24.6 0.4 3.1 1 1 1 2 2 2 1 PQQ-like domain DUF1258 PF06869.7 ETO14374.1 - 1.5e-06 27.5 1.8 0.56 9.2 0.0 4.3 3 2 2 5 5 5 3 Protein of unknown function (DUF1258) DUF4072 PF13284.1 ETO14374.1 - 6e-05 23.1 0.0 11 6.3 0.0 4.9 5 0 0 5 5 5 0 Domain of unknown function (DUF4072) Nucleoporin_N PF08801.6 ETO14374.1 - 0.00029 19.7 6.0 0.5 9.0 0.1 4.1 1 1 2 3 3 3 3 Nup133 N terminal like DUF4221 PF13970.1 ETO14374.1 - 0.00074 18.9 0.3 0.34 10.1 0.0 3.3 1 1 3 4 4 4 1 Domain of unknown function (DUF4221) Proteasome_A_N PF10584.4 ETO14374.1 - 0.00079 18.7 0.7 11 5.4 0.0 4.6 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Nbas_N PF15492.1 ETO14374.1 - 0.00094 18.3 0.8 5.8 5.9 0.0 4.0 1 1 3 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 ETO14374.1 - 0.0011 17.3 0.3 0.021 13.1 0.0 2.4 2 1 1 3 3 3 2 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 ETO14374.1 - 0.0036 16.1 0.1 1.2 7.8 0.0 2.3 1 1 1 2 2 2 2 Coatomer WD associated region DPPIV_N PF00930.16 ETO14374.1 - 0.024 13.2 0.1 17 3.8 0.0 3.5 1 1 3 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF3732 PF12532.3 ETO14374.1 - 0.078 12.4 0.2 7.8 5.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3732) Ricin_B_lectin PF00652.17 ETO14374.1 - 0.15 12.1 1.7 20 5.2 0.2 3.0 1 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain WD40 PF00400.27 ETO14375.1 - 4.4e-77 251.4 25.0 8.5e-13 47.6 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO14375.1 - 7.9e-09 34.1 4.6 0.24 9.4 0.1 5.7 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO14375.1 - 9.6e-07 27.8 9.3 1.9 7.1 0.0 5.8 1 1 5 6 6 6 4 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO14375.1 - 8e-05 21.1 2.1 0.25 9.5 0.0 3.1 1 1 1 3 3 3 2 Cytochrome D1 heme domain Resistin PF06954.6 ETO14375.1 - 0.0021 18.2 0.4 56 4.1 0.0 5.3 5 1 1 6 6 6 0 Resistin SGL PF08450.7 ETO14375.1 - 0.0022 17.4 0.6 0.67 9.2 0.1 2.8 1 1 2 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region PQQ_2 PF13360.1 ETO14375.1 - 0.0028 17.1 0.1 0.13 11.7 0.0 2.7 1 1 0 1 1 1 1 PQQ-like domain SusE PF14292.1 ETO14375.1 - 0.0054 16.5 0.5 10 5.9 0.0 4.0 3 1 1 4 4 4 1 SusE outer membrane protein Me-amine-dh_H PF06433.6 ETO14375.1 - 0.0071 15.0 0.0 0.14 10.7 0.0 2.4 2 0 0 2 2 2 1 Methylamine dehydrogenase heavy chain (MADH) Nbas_N PF15492.1 ETO14375.1 - 0.011 14.7 1.4 2 7.4 0.0 3.9 1 1 3 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Colicin_im PF03857.8 ETO14375.1 - 0.019 14.7 0.3 0.03 14.0 0.2 1.2 1 0 0 1 1 1 0 Colicin immunity protein PD40 PF07676.7 ETO14375.1 - 1 9.0 9.7 2.6 7.7 0.1 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF572 PF04502.8 ETO14378.1 - 0.19 10.8 19.8 0.29 10.3 13.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) LMBR1 PF04791.11 ETO14378.1 - 2.5 6.6 6.7 3.2 6.2 4.6 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Utp14 PF04615.8 ETO14378.1 - 4.1 5.4 28.3 4.7 5.2 19.6 1.1 1 0 0 1 1 1 0 Utp14 protein FH2 PF02181.18 ETO14380.1 - 2.5e-08 33.2 3.8 2.5e-08 33.2 2.6 2.5 1 1 0 2 2 2 1 Formin Homology 2 Domain FAD-SLDH PF12318.3 ETO14380.1 - 0.45 10.1 2.7 0.9 9.2 0.7 2.0 1 1 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase PRD PF00874.15 ETO14380.1 - 5.1 7.2 8.9 0.87 9.7 0.4 3.3 2 1 1 3 3 3 0 PRD domain AA_permease_C PF13906.1 ETO14381.1 - 0.079 12.8 0.3 0.079 12.8 0.2 2.3 2 0 0 2 2 2 0 C-terminus of AA_permease DUF21 PF01595.15 ETO14381.1 - 8.1 5.6 7.6 60 2.8 4.8 2.5 1 1 0 1 1 1 0 Domain of unknown function DUF21 Guanylate_cyc PF00211.15 ETO14382.1 - 4.8e-24 84.7 0.6 2e-23 82.6 0.4 2.1 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Desulfoferrod_N PF06397.7 ETO14382.1 - 1.3 8.4 7.5 5.7 6.4 0.3 2.6 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain CUB PF00431.15 ETO14383.1 - 0.0022 18.0 3.4 0.2 11.7 0.4 2.7 2 0 0 2 2 2 2 CUB domain WD40 PF00400.27 ETO14384.1 - 1.8e-48 160.7 11.4 1.1e-11 44.1 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO14384.1 - 2e-07 30.9 0.0 0.0016 18.1 0.1 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO14384.1 - 3.7e-05 22.0 0.1 0.1 10.7 0.0 2.7 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO14384.1 - 0.00016 20.1 0.0 0.019 13.2 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.7 ETO14384.1 - 0.016 14.8 3.9 0.99 9.1 0.0 4.9 5 1 0 5 5 5 0 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO14384.1 - 0.022 13.5 4.2 0.77 8.4 1.1 3.5 1 1 0 2 2 2 0 Nup133 N terminal like WD40 PF00400.27 ETO14385.1 - 7.5e-86 279.2 23.8 6.6e-13 48.0 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO14385.1 - 5.9e-08 31.3 7.9 0.079 11.0 0.1 5.3 1 1 5 6 6 6 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO14385.1 - 1e-06 27.3 0.8 0.0057 15.0 0.1 3.5 1 1 2 4 4 4 3 Cytochrome D1 heme domain Resistin PF06954.6 ETO14385.1 - 2.7e-05 24.3 1.9 2.2 8.6 0.0 4.2 2 1 2 4 4 4 2 Resistin Nucleoporin_N PF08801.6 ETO14385.1 - 3.8e-05 22.6 14.5 0.042 12.5 0.9 5.2 1 1 3 4 4 4 2 Nup133 N terminal like Nbas_N PF15492.1 ETO14385.1 - 6e-05 22.2 0.7 0.51 9.3 0.0 3.4 1 1 2 3 3 3 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 ETO14385.1 - 0.00017 21.1 3.2 1.8 8.3 0.0 4.4 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat DUF4221 PF13970.1 ETO14385.1 - 0.0015 17.9 0.1 0.66 9.2 0.0 3.5 1 1 3 4 4 4 1 Domain of unknown function (DUF4221) HARP PF07443.8 ETO14385.1 - 0.0053 16.1 0.1 7.1 6.0 0.0 4.3 5 0 0 5 5 5 1 HepA-related protein (HARP) Hira PF07569.6 ETO14385.1 - 0.015 14.5 1.8 5.9 6.0 0.0 4.4 2 1 3 5 5 5 0 TUP1-like enhancer of split DUF1797 PF08796.5 ETO14385.1 - 0.015 15.1 0.0 9.6 6.1 0.0 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1797) Proteasome_A_N PF10584.4 ETO14385.1 - 0.025 13.8 0.1 18 4.7 0.0 3.3 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Guanylate_cyc PF00211.15 ETO14386.1 - 7.7e-20 71.0 0.0 1.1e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain FAM60A PF15396.1 ETO14387.1 - 0.11 12.2 10.6 0.14 11.9 7.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A ATC_hydrolase PF14196.1 ETO14387.1 - 0.26 11.7 4.0 0.31 11.4 2.8 1.1 1 0 0 1 1 1 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase Sre PF03125.13 ETO14387.1 - 0.43 9.4 2.8 0.53 9.1 1.9 1.1 1 0 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor NCD2 PF04905.8 ETO14387.1 - 0.53 10.0 5.9 0.69 9.6 4.1 1.1 1 0 0 1 1 1 0 NAB conserved region 2 (NCD2) Phtf-FEM1B_bdg PF12129.3 ETO14387.1 - 6.3 6.1 7.8 8 5.7 5.4 1.3 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor YMF19 PF02326.10 ETO14387.1 - 9.1 6.9 10.0 26 5.4 6.9 1.8 1 1 0 1 1 1 0 Plant ATP synthase F0 DUF3668 PF12416.3 ETO14388.1 - 2.1e-07 30.4 0.5 0.011 14.9 0.1 2.2 2 0 0 2 2 2 2 Cep120 protein O-ag_pol_Wzy PF14296.1 ETO14388.1 - 0.11 10.9 4.9 0.16 10.4 3.4 1.2 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy DEAD PF00270.24 ETO14390.1 - 7.4e-45 152.4 0.4 7.4e-45 152.4 0.3 2.5 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETO14390.1 - 3.1e-25 87.8 0.0 2e-23 82.0 0.0 3.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Mem_trans PF03547.13 ETO14390.1 - 0.68 8.1 4.1 1.5 7.0 2.9 1.5 1 0 0 1 1 1 0 Membrane transport protein AAA_19 PF13245.1 ETO14390.1 - 1.2 8.9 6.2 0.74 9.6 2.4 2.1 2 1 0 2 2 2 0 Part of AAA domain zf-RING_5 PF14634.1 ETO14391.1 - 0.11 12.2 11.1 0.36 10.5 7.7 2.0 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 ETO14391.1 - 0.32 11.0 8.7 1.4 9.0 6.0 2.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2572 PF10833.3 ETO14393.1 - 0.041 13.3 2.4 0.046 13.1 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) WD40 PF00400.27 ETO14394.1 - 2e-05 24.3 3.3 0.00074 19.3 0.1 3.1 2 1 1 3 3 3 2 WD domain, G-beta repeat Baculo_19 PF04798.7 ETO14394.1 - 0.05 12.9 1.6 0.077 12.3 0.6 1.8 1 1 1 2 2 2 0 Baculovirus 19 kDa protein conserved region WD40 PF00400.27 ETO14395.1 - 3.3e-18 64.7 0.7 2.8e-09 36.4 0.0 3.1 2 1 1 3 3 3 3 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO14395.1 - 0.0019 18.2 3.2 0.18 12.0 0.2 2.6 2 0 0 2 2 2 2 Kelch motif COG2 PF06148.6 ETO14396.1 - 0.018 14.9 0.1 0.029 14.2 0.1 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Rieske PF00355.21 ETO14397.1 - 1.2e-06 27.9 0.3 0.00011 21.6 0.2 2.4 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain ATP-synt_G PF04718.10 ETO14398.1 - 0.0064 17.1 0.0 0.013 16.0 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit Pribosyltran PF00156.22 ETO14399.1 - 2.9e-19 69.0 0.0 4.1e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 ETO14399.1 - 0.037 13.2 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 ETO14399.1 - 0.092 12.0 0.0 0.25 10.6 0.0 1.6 2 0 0 2 2 2 0 Phosphoribosyl transferase FragX_IP PF05994.6 ETO14400.1 - 0.00014 19.8 0.0 0.00018 19.4 0.0 1.1 1 0 0 1 1 1 1 Cytoplasmic Fragile-X interacting family FragX_IP PF05994.6 ETO14401.1 - 3.6e-110 369.0 6.8 5e-110 368.6 4.7 1.1 1 0 0 1 1 1 1 Cytoplasmic Fragile-X interacting family Peptidase_M15_4 PF13539.1 ETO14401.1 - 0.13 12.6 0.0 1.1 9.8 0.0 2.3 3 0 0 3 3 3 0 D-alanyl-D-alanine carboxypeptidase FragX_IP PF05994.6 ETO14402.1 - 4.3e-22 77.7 0.0 8.3e-22 76.8 0.0 1.3 1 0 0 1 1 1 1 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.7 ETO14402.1 - 0.00084 18.5 0.1 0.0014 17.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) WD40 PF00400.27 ETO14404.1 - 6.8e-83 269.8 12.9 1.5e-12 46.8 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO14404.1 - 1.1e-14 53.5 6.7 0.025 12.7 0.0 5.8 1 1 4 5 5 5 5 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO14404.1 - 5.3e-10 39.1 2.6 2.1e-05 24.1 0.1 2.3 1 1 0 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 ETO14404.1 - 1.7e-07 30.4 6.5 0.08 11.6 0.3 5.0 1 1 2 4 4 4 4 Nup133 N terminal like Me-amine-dh_H PF06433.6 ETO14404.1 - 9.3e-06 24.4 0.2 0.01 14.5 0.0 2.6 2 1 1 3 3 3 2 Methylamine dehydrogenase heavy chain (MADH) Nbas_N PF15492.1 ETO14404.1 - 5.7e-05 22.3 0.2 0.011 14.8 0.0 3.4 2 2 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Hira PF07569.6 ETO14404.1 - 0.00022 20.4 0.6 0.17 11.0 0.0 3.6 2 1 1 3 3 3 1 TUP1-like enhancer of split PQQ PF01011.16 ETO14404.1 - 0.00034 19.9 0.0 7.1 6.3 0.0 5.0 5 0 0 5 5 5 1 PQQ enzyme repeat Cytochrom_D1 PF02239.11 ETO14404.1 - 0.00039 18.8 0.6 1.1 7.4 0.0 3.2 1 1 1 3 3 3 1 Cytochrome D1 heme domain Gmad1 PF10647.4 ETO14404.1 - 0.002 17.5 0.1 0.029 13.7 0.0 2.5 1 1 1 2 2 2 1 Lipoprotein LpqB beta-propeller domain PD40 PF07676.7 ETO14404.1 - 0.0024 17.4 4.3 5.2 6.8 0.0 4.3 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 ETO14404.1 - 0.0072 15.4 5.1 2.9 6.8 0.0 4.6 1 1 3 5 5 5 1 Protein of unknown function (DUF1258) Resistin PF06954.6 ETO14404.1 - 0.012 15.8 1.0 54 4.1 0.0 4.2 3 1 1 4 4 4 0 Resistin Adeno_knob PF00541.12 ETO14404.1 - 0.053 13.1 0.1 1.6 8.3 0.0 3.0 1 1 1 3 3 3 0 Adenoviral fibre protein (knob domain) DUF1924 PF09086.6 ETO14404.1 - 0.095 12.7 0.1 0.29 11.2 0.0 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF1924) DUF2963 PF11178.3 ETO14404.1 - 0.74 9.2 0.0 0.74 9.2 0.0 4.0 5 1 0 5 5 4 0 Protein of unknown function (DUF2963) Peptidase_C14 PF00656.17 ETO14405.1 - 6.9e-09 35.7 0.2 6.9e-09 35.7 0.2 2.5 2 1 0 2 2 2 1 Caspase domain Kelch_1 PF01344.20 ETO14405.1 - 0.0013 18.2 0.6 0.0013 18.2 0.4 3.2 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 ETO14405.1 - 0.0059 16.7 0.3 0.027 14.6 0.2 2.2 1 0 0 1 1 1 1 Kelch motif Kelch_4 PF13418.1 ETO14405.1 - 0.048 13.4 0.1 0.15 11.8 0.1 1.8 1 0 0 1 1 1 0 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO14405.1 - 0.087 12.8 0.2 0.2 11.6 0.2 1.6 1 0 0 1 1 1 0 Kelch motif SprA-related PF12118.3 ETO14405.1 - 0.3 10.3 12.5 0.44 9.8 8.7 1.2 1 0 0 1 1 1 0 SprA-related family RNA_pol_Rpb1_5 PF04998.12 ETO14405.1 - 1.1 8.4 7.6 2.4 7.3 5.3 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Mit_ribos_Mrp51 PF11709.3 ETO14405.1 - 4 6.5 14.6 0.095 11.9 4.8 2.1 1 1 1 2 2 2 0 Mitochondrial ribosomal protein subunit DDHD PF02862.12 ETO14405.1 - 4.2 7.0 12.0 8.3 6.1 8.3 1.5 1 0 0 1 1 1 0 DDHD domain AAA_11 PF13086.1 ETO14405.1 - 8 5.9 10.3 18 4.7 7.1 1.6 1 0 0 1 1 1 0 AAA domain Vac14_Fig4_bd PF11916.3 ETO14406.1 - 4.6e-41 139.9 18.8 1.7e-40 138.1 6.0 2.6 2 1 0 2 2 2 2 Vacuolar protein 14 C-terminal Fig4p binding HEAT_2 PF13646.1 ETO14406.1 - 0.013 15.7 0.5 0.1 12.8 0.1 2.3 2 0 0 2 2 2 0 HEAT repeats HEAT PF02985.17 ETO14406.1 - 0.041 13.9 2.1 0.23 11.6 0.2 2.6 2 0 0 2 2 2 0 HEAT repeat RecO_C PF02565.10 ETO14406.1 - 0.74 9.6 4.7 0.52 10.1 0.6 2.4 2 0 0 2 2 2 0 Recombination protein O C terminal HEAT_EZ PF13513.1 ETO14406.1 - 2 9.0 5.1 3.2 8.3 0.1 3.1 3 0 0 3 3 3 0 HEAT-like repeat CLASP_N PF12348.3 ETO14407.1 - 1.5e-06 27.7 0.3 9.7e-05 21.8 0.0 2.1 1 1 1 2 2 2 1 CLASP N terminal Cnd1 PF12717.2 ETO14407.1 - 5.6e-05 23.0 1.2 0.056 13.2 0.2 2.3 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 ETO14407.1 - 0.0022 18.3 0.0 0.22 11.9 0.0 2.1 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region Dopey_N PF04118.9 ETO14407.1 - 0.0043 15.8 0.7 0.011 14.5 0.5 1.6 1 1 0 1 1 1 1 Dopey, N-terminal HEAT PF02985.17 ETO14407.1 - 0.0048 16.8 0.6 22 5.4 0.0 3.6 4 0 0 4 4 4 0 HEAT repeat SMK-1 PF04802.10 ETO14407.1 - 0.0049 16.4 0.3 0.028 13.9 0.1 2.2 2 1 0 2 2 2 1 Component of IIS longevity pathway SMK-1 HEAT_EZ PF13513.1 ETO14407.1 - 0.0095 16.4 0.0 7 7.2 0.0 2.8 3 0 0 3 3 3 2 HEAT-like repeat HEAT_2 PF13646.1 ETO14407.1 - 0.018 15.2 0.0 2.5 8.4 0.0 2.4 2 0 0 2 2 2 0 HEAT repeats ATP-synt_ab PF00006.20 ETO14408.1 - 6.2e-27 94.5 1.5 7.2e-24 84.4 0.1 2.0 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.7 ETO14408.1 - 0.02 14.5 0.3 0.13 11.8 0.1 2.1 1 1 0 2 2 2 0 NACHT domain AAA_25 PF13481.1 ETO14408.1 - 0.036 13.4 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 ETO14408.1 - 0.062 12.9 0.0 0.078 12.6 0.0 1.1 1 0 0 1 1 1 0 Archaeal ATPase DUF258 PF03193.11 ETO14408.1 - 0.069 12.3 0.0 0.099 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NB-ARC PF00931.17 ETO14408.1 - 0.15 10.8 0.5 0.21 10.4 0.4 1.2 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 ETO14408.1 - 0.16 12.2 0.3 0.28 11.4 0.2 1.4 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 ETO14408.1 - 0.16 11.8 0.1 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 ETO14408.1 - 0.17 11.2 0.2 0.23 10.8 0.2 1.1 1 0 0 1 1 1 0 AAA-like domain KaiC PF06745.8 ETO14408.1 - 0.17 10.9 0.6 0.22 10.5 0.4 1.2 1 0 0 1 1 1 0 KaiC ATP-synt_ab_C PF00306.22 ETO14409.1 - 6.2e-18 65.3 0.9 7.3e-18 65.0 0.6 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain DivIC PF04977.10 ETO14409.1 - 0.084 12.3 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 Septum formation initiator Cofilin_ADF PF00241.15 ETO14410.1 - 5e-20 71.6 2.9 8.9e-11 41.7 0.5 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein WD40 PF00400.27 ETO14411.1 - 3.5e-72 235.9 13.2 1.5e-12 46.8 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO14411.1 - 4.5e-11 42.4 5.1 2e-05 24.5 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Nup160 PF11715.3 ETO14411.1 - 5.8e-06 24.7 1.2 0.65 8.0 0.0 4.6 1 1 2 4 4 4 2 Nucleoporin Nup120/160 Kelch_1 PF01344.20 ETO14411.1 - 5.4e-05 22.6 8.6 0.011 15.2 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO14411.1 - 0.00014 21.7 1.2 0.3 11.0 0.0 4.3 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.1 ETO14411.1 - 0.00024 20.8 0.6 0.075 12.8 0.0 4.4 4 1 1 5 5 5 1 Galactose oxidase, central domain PQQ_2 PF13360.1 ETO14411.1 - 0.00034 20.1 0.4 0.36 10.2 0.1 2.9 1 1 1 3 3 3 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO14411.1 - 0.0028 15.9 0.3 0.27 9.4 0.0 3.1 1 1 2 3 3 3 2 Cytochrome D1 heme domain Kelch_3 PF13415.1 ETO14411.1 - 0.0041 17.2 0.4 0.9 9.7 0.0 3.8 3 0 0 3 3 3 1 Galactose oxidase, central domain PD40 PF07676.7 ETO14411.1 - 0.016 14.9 14.1 4.1 7.1 0.1 6.0 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Kelch_2 PF07646.10 ETO14411.1 - 0.031 14.0 5.4 5.4 6.9 0.1 4.5 4 1 0 4 4 4 0 Kelch motif Nop25 PF09805.4 ETO14412.1 - 3.3 7.7 21.5 6.4 6.8 14.9 1.5 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) TBX PF12598.3 ETO14412.1 - 4 7.8 11.3 0.59 10.5 4.2 2.0 1 1 1 2 2 2 0 T-box transcription factor DDRGK PF09756.4 ETO14412.1 - 7.3 5.9 16.5 12 5.2 11.4 1.5 1 1 0 1 1 1 0 DDRGK domain DEAD PF00270.24 ETO14413.1 - 1.6e-41 141.6 0.0 3.9e-41 140.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETO14413.1 - 2e-19 69.2 0.0 5e-19 67.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 ETO14413.1 - 1.6e-10 40.3 0.1 3.5e-10 39.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 ETO14413.1 - 6.8e-06 26.0 3.9 0.00018 21.4 0.0 3.0 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 ETO14413.1 - 0.071 13.0 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 Helicase C-terminal domain Glycolytic PF00274.14 ETO14414.1 - 3.9e-67 226.0 0.0 4.4e-67 225.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I GAF_3 PF13492.1 ETO14415.1 - 0.00011 22.2 0.1 0.00047 20.2 0.0 2.0 1 1 0 1 1 1 1 GAF domain GAF_2 PF13185.1 ETO14415.1 - 0.00012 22.6 0.0 0.0011 19.5 0.0 2.3 1 1 0 1 1 1 1 GAF domain GAF PF01590.21 ETO14415.1 - 0.00026 21.1 0.1 0.016 15.3 0.0 3.0 2 1 0 2 2 2 1 GAF domain PAS_4 PF08448.5 ETO14415.1 - 0.029 14.4 0.0 0.18 11.8 0.0 2.3 3 0 0 3 3 3 0 PAS fold TPR_12 PF13424.1 ETO14416.1 - 6.1e-13 48.5 0.7 3.3e-12 46.1 0.2 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO14416.1 - 1e-08 34.4 8.2 1.3e-05 24.6 1.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO14416.1 - 9.1e-08 31.6 3.7 2e-07 30.5 0.9 2.4 2 1 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 ETO14416.1 - 1.8e-07 30.5 4.8 0.002 17.8 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO14416.1 - 1.1e-06 27.9 0.2 0.019 14.7 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO14416.1 - 1.2e-05 24.7 8.4 0.025 14.3 0.7 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO14416.1 - 1.3e-05 24.9 0.0 0.081 12.8 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF2225 PF09986.4 ETO14416.1 - 0.001 18.5 7.2 0.02 14.3 0.7 2.0 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) Apc3 PF12895.2 ETO14416.1 - 0.0024 17.9 6.0 0.0024 17.9 0.9 2.6 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 ETO14416.1 - 0.017 14.9 2.8 0.7 9.8 0.1 3.1 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain P22_AR_C PF10548.4 ETO14416.1 - 0.025 14.4 0.3 1.5 8.7 0.0 2.5 2 0 0 2 2 2 0 P22AR C-terminal domain TPR_17 PF13431.1 ETO14416.1 - 1.1 9.5 5.1 0.99 9.7 0.3 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat Ank PF00023.25 ETO14417.1 - 5.7e-34 114.2 2.1 1.6e-06 27.6 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 ETO14417.1 - 5.8e-34 116.3 0.3 6.9e-13 48.7 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO14417.1 - 5.3e-28 96.4 2.7 4.2e-07 30.0 0.0 5.5 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO14417.1 - 5.8e-27 91.0 2.1 4e-05 23.4 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 ETO14417.1 - 4e-23 81.3 1.0 4.8e-11 42.8 0.0 4.2 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Reo_sigmaC PF04582.7 ETO14418.1 - 0.12 11.5 0.5 0.28 10.3 0.3 1.7 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Laminin_I PF06008.9 ETO14418.1 - 0.29 10.4 28.5 0.97 8.6 6.2 3.5 2 1 1 3 3 3 0 Laminin Domain I ATG16 PF08614.6 ETO14418.1 - 0.41 10.4 37.0 0.059 13.2 10.1 3.5 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.7 ETO14418.1 - 5.2 6.8 27.5 0.089 12.5 3.3 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.2 ETO14418.1 - 6.1 6.6 25.9 5.1 6.9 0.6 3.9 2 1 0 3 3 3 0 Tropomyosin like Col_cuticle_N PF01484.12 ETO14418.1 - 7.3 6.3 8.5 14 5.4 0.1 3.7 4 0 0 4 4 4 0 Nematode cuticle collagen N-terminal domain WD40 PF00400.27 ETO14419.1 - 9e-25 85.6 6.2 1.1e-07 31.4 1.0 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 ETO14419.1 - 3.7e-08 33.1 1.1 0.00056 19.6 0.2 4.5 4 0 0 4 4 4 2 Ciliary BBSome complex subunit 2, middle region MraZ PF02381.13 ETO14419.1 - 0.059 13.1 0.2 6.6 6.5 0.0 2.8 2 0 0 2 2 2 0 MraZ protein PQQ_3 PF13570.1 ETO14419.1 - 0.2 11.9 0.0 16 5.8 0.0 2.8 2 0 0 2 2 2 0 PQQ-like domain Uds1 PF15456.1 ETO14419.1 - 2.2 8.2 9.6 10 6.1 6.6 2.0 1 1 0 1 1 1 0 Up-regulated During Septation FerA PF08165.6 ETO14420.1 - 0.039 13.6 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 FerA (NUC095) domain PRE_C2HC PF07530.6 ETO14420.1 - 0.047 13.5 0.4 7.8 6.4 0.1 2.3 2 1 0 2 2 2 0 Associated with zinc fingers ATP-grasp_3 PF02655.9 ETO14420.1 - 0.048 13.5 0.0 0.053 13.3 0.0 1.1 1 0 0 1 1 1 0 ATP-grasp domain Plasmodium_Vir PF05795.6 ETO14421.1 - 2.2e-05 23.8 1.8 2.8e-05 23.5 1.2 1.2 1 0 0 1 1 1 1 Plasmodium vivax Vir protein CDC45 PF02724.9 ETO14421.1 - 0.00019 19.6 11.2 0.00021 19.4 7.7 1.0 1 0 0 1 1 1 1 CDC45-like protein Raftlin PF15250.1 ETO14421.1 - 0.00068 18.2 2.1 0.00076 18.1 1.5 1.0 1 0 0 1 1 1 1 Raftlin Cwf_Cwc_15 PF04889.7 ETO14421.1 - 0.02 14.6 15.8 0.024 14.3 10.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Prog_receptor PF02161.10 ETO14421.1 - 0.026 13.3 5.6 0.03 13.1 3.9 1.0 1 0 0 1 1 1 0 Progesterone receptor YL1 PF05764.8 ETO14421.1 - 0.032 13.8 21.4 0.044 13.3 14.8 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Daxx PF03344.10 ETO14421.1 - 0.058 11.8 21.7 0.066 11.6 15.0 1.1 1 0 0 1 1 1 0 Daxx Family DUF4628 PF15429.1 ETO14421.1 - 0.064 12.6 3.1 0.089 12.2 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) DUF2146 PF10220.4 ETO14421.1 - 0.071 11.0 5.4 0.076 10.9 3.8 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Peptidase_A22B PF04258.8 ETO14421.1 - 0.072 12.5 0.0 0.092 12.1 0.0 1.1 1 0 0 1 1 1 0 Signal peptide peptidase SDA1 PF05285.7 ETO14421.1 - 0.14 11.3 22.4 0.17 11.1 15.5 1.1 1 0 0 1 1 1 0 SDA1 Sporozoite_P67 PF05642.6 ETO14421.1 - 0.23 9.3 7.8 0.23 9.2 5.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PPP4R2 PF09184.6 ETO14421.1 - 0.45 10.0 25.4 0.24 10.8 16.4 1.3 2 0 0 2 2 1 0 PPP4R2 Nop14 PF04147.7 ETO14421.1 - 0.47 8.3 25.4 0.54 8.1 17.6 1.0 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.8 ETO14421.1 - 0.72 8.5 14.6 0.84 8.2 10.1 1.3 1 0 0 1 1 1 0 Paf1 SAPS PF04499.10 ETO14421.1 - 0.89 8.1 6.5 0.97 7.9 4.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2722 PF10846.3 ETO14421.1 - 1 8.3 9.3 1.1 8.1 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Trypan_PARP PF05887.6 ETO14421.1 - 1 9.1 12.3 1.3 8.8 8.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) VID27 PF08553.5 ETO14421.1 - 1.2 7.2 15.3 1.4 7.0 10.6 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF1510 PF07423.6 ETO14421.1 - 1.4 8.2 18.7 2.2 7.6 13.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RRN3 PF05327.6 ETO14421.1 - 1.4 6.9 12.3 1.5 6.7 8.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NOA36 PF06524.7 ETO14421.1 - 1.5 8.0 20.4 2.1 7.5 14.1 1.1 1 0 0 1 1 1 0 NOA36 protein BUD22 PF09073.5 ETO14421.1 - 2 7.3 20.4 2.6 7.0 14.2 1.1 1 0 0 1 1 1 0 BUD22 Retinal PF15449.1 ETO14421.1 - 3.5 5.1 8.8 4.1 4.9 6.1 1.1 1 0 0 1 1 1 0 Retinal protein Spore_coat_CotO PF14153.1 ETO14421.1 - 3.9 6.8 11.9 5.2 6.4 8.3 1.2 1 0 0 1 1 1 0 Spore coat protein CotO SAE2 PF08573.5 ETO14421.1 - 6.1 7.6 9.6 12 6.6 6.7 1.5 1 1 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus TFIIF_alpha PF05793.7 ETO14421.1 - 6.7 4.9 26.1 7.8 4.7 18.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2987 PF11205.3 ETO14423.1 - 1.2 8.7 5.7 1.4 8.6 3.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2987) RRM_6 PF14259.1 ETO14424.1 - 2.2e-05 24.3 0.0 4.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO14424.1 - 0.0029 17.1 0.0 0.013 15.1 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RepA_C PF04796.7 ETO14425.1 - 0.019 14.5 0.4 0.06 12.9 0.2 1.9 1 0 0 1 1 1 0 Plasmid encoded RepA protein FANCL_C PF11793.3 ETO14425.1 - 0.056 13.4 0.2 0.2 11.6 0.0 2.1 2 0 0 2 2 2 0 FANCL C-terminal domain z-alpha PF02295.12 ETO14426.1 - 0.15 11.8 2.8 0.49 10.1 0.3 2.3 2 0 0 2 2 2 0 Adenosine deaminase z-alpha domain FAM60A PF15396.1 ETO14426.1 - 6.6 6.4 16.9 6.4 6.4 7.5 2.2 2 1 0 2 2 2 0 Protein Family FAM60A PFO_beta_C PF12367.3 ETO14427.1 - 0.084 12.8 1.1 0.29 11.0 0.7 2.0 1 0 0 1 1 1 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal Kinetocho_Slk19 PF12709.2 ETO14427.1 - 7.4 6.7 36.5 3.2 7.8 3.9 4.5 2 2 2 4 4 4 0 Central kinetochore-associated TRCF PF03461.10 ETO14428.1 - 0.022 14.7 7.9 0.077 12.9 0.2 3.1 2 1 1 3 3 3 0 TRCF domain LOH1CR12 PF10158.4 ETO14428.1 - 0.051 13.3 11.6 0.26 11.0 1.6 3.0 1 1 1 3 3 3 0 Tumour suppressor protein AMP-binding_C_2 PF14535.1 ETO14428.1 - 0.095 12.7 0.3 0.095 12.7 0.2 3.5 1 1 2 3 3 3 0 AMP-binding enzyme C-terminal domain YPEB PF14620.1 ETO14428.1 - 0.23 10.4 23.5 0.3 10.0 7.2 2.9 1 1 2 3 3 3 0 YpeB sporulation PhoU PF01895.14 ETO14428.1 - 9.4 6.7 8.2 1.4 9.3 0.7 2.6 1 1 1 2 2 2 0 PhoU domain UCH PF00443.24 ETO14429.1 - 7.3e-36 123.6 8.9 1.4e-35 122.7 2.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase GST_N_2 PF13409.1 ETO14430.1 - 0.027 14.4 0.1 0.05 13.6 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain H_PPase PF03030.11 ETO14431.1 - 5.6e-34 117.4 8.0 5.1e-28 97.7 1.5 2.1 2 0 0 2 2 2 2 Inorganic H+ pyrophosphatase Ni_hydr_CYTB PF01292.15 ETO14431.1 - 0.011 15.1 0.1 0.013 14.8 0.1 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 H_PPase PF03030.11 ETO14432.1 - 3.3e-11 42.1 0.1 3.9e-11 41.9 0.1 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase H_PPase PF03030.11 ETO14433.1 - 3.8e-81 273.3 10.9 2.5e-80 270.6 7.5 1.9 1 1 0 1 1 1 1 Inorganic H+ pyrophosphatase DUF373 PF04123.8 ETO14433.1 - 0.032 13.2 0.4 0.032 13.2 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF373) DUF1761 PF08570.5 ETO14433.1 - 0.054 13.5 8.3 4.8 7.2 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1761) DUF1469 PF07332.6 ETO14433.1 - 0.14 11.9 0.0 0.14 11.9 0.0 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1469) RhoGAP PF00620.22 ETO14434.1 - 1.3e-17 63.7 1.0 3.7e-17 62.3 0.1 2.2 2 0 0 2 2 2 1 RhoGAP domain LRR_6 PF13516.1 ETO14434.1 - 3.2e-07 29.7 25.6 0.0015 18.3 0.1 7.7 9 0 0 9 9 9 3 Leucine Rich repeat Nop14 PF04147.7 ETO14434.1 - 0.098 10.5 18.2 0.19 9.5 12.6 1.4 1 0 0 1 1 1 0 Nop14-like family LRR_4 PF12799.2 ETO14434.1 - 0.41 10.3 26.3 0.7 9.5 0.6 6.2 7 1 1 8 8 8 0 Leucine Rich repeats (2 copies) CDC45 PF02724.9 ETO14434.1 - 1.5 6.7 17.2 2.6 5.9 11.9 1.3 1 0 0 1 1 1 0 CDC45-like protein LRR_1 PF00560.28 ETO14434.1 - 7.9 6.9 21.4 3 8.2 0.9 7.6 7 1 0 7 7 7 0 Leucine Rich Repeat Cpn60_TCP1 PF00118.19 ETO14435.1 - 7.7e-52 176.5 0.7 4.5e-40 137.7 0.1 2.0 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.19 ETO14436.1 - 1e-64 219.0 2.3 1.4e-64 218.5 1.6 1.2 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rad60-SLD PF11976.3 ETO14437.1 - 3.1e-16 58.8 0.0 4.7e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 ETO14437.1 - 7.7e-05 22.0 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family CEP19 PF14933.1 ETO14437.1 - 0.06 13.6 0.1 0.074 13.3 0.0 1.2 1 0 0 1 1 1 0 CEP19-like protein SOBP PF15279.1 ETO14439.1 - 2.8 8.2 14.1 3.1 8.1 9.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein V_ATPase_I PF01496.14 ETO14439.1 - 5.1 4.8 12.0 5.1 4.8 8.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Borrelia_P83 PF05262.6 ETO14439.1 - 5.8 5.0 20.7 5.9 5.0 14.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein AUX_IAA PF02309.11 ETO14439.1 - 8 6.1 20.9 11 5.6 14.5 1.2 1 0 0 1 1 1 0 AUX/IAA family DUF2011 PF09428.5 ETO14440.1 - 0.01 15.7 1.6 0.01 15.7 1.1 2.0 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF2011) DUF853 PF05872.7 ETO14440.1 - 0.084 11.2 1.6 0.085 11.1 1.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) MIP-T3 PF10243.4 ETO14440.1 - 0.66 8.3 30.2 0.73 8.2 20.9 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Daxx PF03344.10 ETO14440.1 - 0.73 8.2 33.5 0.92 7.9 23.2 1.0 1 0 0 1 1 1 0 Daxx Family Parvo_coat PF00740.13 ETO14440.1 - 1.4 7.8 4.4 1.5 7.7 3.0 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Nop14 PF04147.7 ETO14440.1 - 3.2 5.5 28.1 3.4 5.4 19.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2201_N PF13203.1 ETO14440.1 - 3.7 6.6 9.9 5.4 6.0 6.9 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Peptidase_S30 PF01577.11 ETO14440.1 - 4.8 6.5 6.1 1.4 8.2 1.8 1.8 2 0 0 2 2 2 0 Potyvirus P1 protease Hid1 PF12722.2 ETO14440.1 - 5.6 4.5 10.9 5.8 4.4 7.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Peptidase_C78 PF07910.8 ETO14442.1 - 1.7e-07 30.5 0.2 1.7e-07 30.5 0.2 1.8 2 0 0 2 2 2 1 Peptidase family C78 ETRAMP PF09716.5 ETO14442.1 - 0.00028 20.7 0.2 0.00028 20.7 0.2 2.8 3 1 0 3 3 3 1 Malarial early transcribed membrane protein (ETRAMP) zf-met PF12874.2 ETO14442.1 - 0.024 14.8 0.5 0.064 13.4 0.3 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Neur_chan_memb PF02932.11 ETO14442.1 - 0.82 9.5 4.0 0.15 11.8 0.2 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region zf-C2H2_4 PF13894.1 ETO14442.1 - 1 9.8 5.4 0.25 11.7 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger FliJ PF02050.11 ETO14443.1 - 0.032 14.2 10.0 0.051 13.6 6.9 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein DUF4144 PF13642.1 ETO14443.1 - 0.13 12.5 2.7 0.17 12.2 0.2 2.1 1 1 0 2 2 2 0 protein structure with unknown function IncA PF04156.9 ETO14443.1 - 0.22 11.0 11.2 0.26 10.8 7.8 1.2 1 0 0 1 1 1 0 IncA protein MbeD_MobD PF04899.7 ETO14443.1 - 0.23 11.4 2.6 0.28 11.0 0.8 1.9 1 1 0 1 1 1 0 MbeD/MobD like RTX PF02382.10 ETO14443.1 - 0.29 9.3 3.6 0.31 9.2 2.5 1.1 1 0 0 1 1 1 0 RTX N-terminal domain TPR_MLP1_2 PF07926.7 ETO14443.1 - 0.3 10.8 16.6 0.68 9.6 11.5 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Pox_A_type_inc PF04508.7 ETO14443.1 - 0.67 9.8 0.0 0.67 9.8 0.0 3.1 3 1 0 3 3 3 0 Viral A-type inclusion protein repeat Arc_PepC PF06819.6 ETO14443.1 - 1.1 9.2 5.9 2.6 8.0 2.1 2.2 1 1 1 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain bZIP_Maf PF03131.12 ETO14443.1 - 1.1 9.6 7.1 3.6 7.9 0.4 3.1 1 1 2 3 3 3 0 bZIP Maf transcription factor DUF3573 PF12097.3 ETO14443.1 - 1.5 7.3 6.7 1.7 7.1 4.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) DUF4140 PF13600.1 ETO14443.1 - 1.9 8.9 4.6 20 5.7 0.1 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) FlxA PF14282.1 ETO14443.1 - 3 7.8 12.4 0.08 12.8 3.8 2.1 2 1 0 2 2 2 0 FlxA-like protein DivIC PF04977.10 ETO14443.1 - 5.6 6.5 10.9 1.1 8.7 1.0 2.7 1 1 1 2 2 2 0 Septum formation initiator DUF342 PF03961.8 ETO14443.1 - 5.9 5.1 10.9 7.5 4.8 7.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Kelch_6 PF13964.1 ETO14444.1 - 1e-07 31.8 5.4 0.013 15.6 0.2 5.1 5 1 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO14444.1 - 2.4e-07 30.1 6.3 0.00017 21.0 0.5 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO14444.1 - 2.2e-06 27.6 0.1 2.7e-05 24.2 0.0 2.9 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO14444.1 - 2.8e-06 27.1 0.8 0.013 15.4 0.3 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO14444.1 - 8.2e-05 22.2 2.2 0.18 11.6 0.1 4.1 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO14444.1 - 0.0013 18.4 0.6 0.6 9.9 0.1 3.8 3 1 1 4 4 4 1 Galactose oxidase, central domain EF-hand_4 PF12763.2 ETO14445.1 - 9.1e-07 28.5 0.0 1.9e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.1 ETO14445.1 - 0.0045 16.2 0.1 0.011 15.0 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 ETO14445.1 - 0.018 15.1 0.7 0.044 13.9 0.5 1.7 1 0 0 1 1 1 0 EF-hand domain pair Sarcoglycan_2 PF05510.8 ETO14445.1 - 0.024 12.9 0.0 0.038 12.2 0.0 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon EF-hand_1 PF00036.27 ETO14445.1 - 0.035 13.4 0.2 0.16 11.3 0.1 2.1 2 0 0 2 2 2 0 EF hand Neur_chan_memb PF02932.11 ETO14445.1 - 0.045 13.6 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EF-hand_6 PF13405.1 ETO14445.1 - 0.086 12.7 0.4 1.8 8.6 0.2 2.7 1 1 1 2 2 2 0 EF-hand domain WD40 PF00400.27 ETO14446.1 - 1.4e-118 383.0 43.8 3.2e-10 39.4 0.1 15.2 15 0 0 15 15 15 14 WD domain, G-beta repeat Nup160 PF11715.3 ETO14446.1 - 5.4e-13 47.9 37.6 0.00095 17.4 0.4 11.3 1 1 10 11 11 11 9 Nucleoporin Nup120/160 Mid2 PF04478.7 ETO14446.1 - 0.00068 19.0 20.7 1.5 8.2 0.3 7.5 7 1 1 8 8 8 3 Mid2 like cell wall stress sensor DUF2441 PF10386.4 ETO14446.1 - 0.0024 17.9 0.2 2.2 8.3 0.0 4.5 2 2 1 4 4 4 1 Protein of unknown function (DUF2441) PD40 PF07676.7 ETO14446.1 - 0.019 14.6 5.1 34 4.2 0.0 6.0 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat PB1-F2 PF11986.3 ETO14446.1 - 0.71 9.9 8.6 1.7 8.7 0.1 4.3 4 1 0 4 4 4 0 Influenza A Proapoptotic protein ubiquitin PF00240.18 ETO14454.1 - 2.2e-08 33.3 0.3 5.7e-08 32.0 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.1 ETO14454.1 - 1.4e-05 24.9 0.2 4.9e-05 23.1 0.1 1.9 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 ETO14454.1 - 0.00013 22.0 0.1 0.00013 22.0 0.1 2.4 3 0 0 3 3 3 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.3 ETO14454.1 - 5.6 6.7 8.9 0.11 12.1 0.2 2.7 3 1 1 4 4 4 0 Ubiquitin-2 like Rad60 SUMO-like DUF3091 PF11291.3 ETO14455.1 - 0.083 12.8 3.5 0.09 12.7 1.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3091) DUF1882 PF08966.6 ETO14455.1 - 0.1 12.5 1.4 13 5.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1882) RICH PF05062.7 ETO14455.1 - 0.2 11.8 4.8 0.26 11.4 2.1 2.1 2 1 0 2 2 2 0 RICH domain DEP PF00610.16 ETO14456.1 - 1.6e-34 117.4 1.6 7.9e-19 67.1 0.1 2.2 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ADH_zinc_N PF00107.21 ETO14458.1 - 2.9e-24 85.0 0.0 4.6e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETO14458.1 - 4.1e-20 72.9 0.0 7.2e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETO14458.1 - 1.3e-08 34.5 0.2 2.4e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PH PF00169.24 ETO14459.1 - 4.4e-09 36.4 10.3 7.5e-05 22.8 3.3 4.1 3 1 0 3 3 3 2 PH domain Mcp5_PH PF12814.2 ETO14459.1 - 0.00026 20.8 0.1 0.1 12.5 0.1 2.8 2 0 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology MBT PF02820.13 ETO14459.1 - 0.00083 19.2 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 mbt repeat PH_2 PF08458.5 ETO14459.1 - 0.0011 18.8 0.0 0.082 12.8 0.0 2.7 2 0 0 2 2 2 1 Plant pleckstrin homology-like region RasGEF PF00617.14 ETO14461.1 - 4.3e-33 114.6 1.1 8e-33 113.7 0.2 1.8 2 0 0 2 2 2 1 RasGEF domain zf-BED PF02892.10 ETO14461.1 - 0.0018 17.9 1.7 0.0048 16.6 1.2 1.7 1 0 0 1 1 1 1 BED zinc finger CobT PF06213.7 ETO14462.1 - 0.00037 19.7 17.4 0.00059 19.0 12.1 1.5 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 ETO14462.1 - 1.9 6.3 36.9 2.5 5.8 25.5 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 ETO14462.1 - 4.8 5.5 33.3 6.1 5.1 23.1 1.2 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 ETO14462.1 - 6.4 5.7 33.8 9.6 5.1 23.5 1.3 1 0 0 1 1 1 0 BUD22 MIP-T3 PF10243.4 ETO14464.1 - 1.2 7.5 30.1 1.4 7.2 20.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 BTV_NS2 PF04514.7 ETO14464.1 - 3.7 6.3 27.9 4.9 5.9 19.3 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 TFIIA PF03153.8 ETO14465.1 - 0.58 9.9 23.3 0.76 9.6 16.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RAP1 PF07218.6 ETO14465.1 - 8.9 4.2 9.4 11 4.0 6.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4181 PF13789.1 ETO14466.1 - 0.018 14.9 9.3 0.04 13.8 6.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) DUF2160 PF09928.4 ETO14466.1 - 0.57 10.3 4.3 0.57 10.3 1.7 2.1 1 1 0 1 1 1 0 Predicted small integral membrane protein (DUF2160) DUF386 PF04074.7 ETO14467.1 - 0.087 12.3 2.3 0.18 11.2 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF386) RRM_1 PF00076.17 ETO14468.1 - 7.6e-07 28.6 0.0 1.9e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO14468.1 - 0.0013 18.6 0.0 0.0038 17.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO14468.1 - 0.01 15.6 0.0 0.023 14.5 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4015 PF13200.1 ETO14468.1 - 0.037 12.9 0.1 0.05 12.5 0.1 1.1 1 0 0 1 1 1 0 Putative glycosyl hydrolase domain RRM_1 PF00076.17 ETO14469.1 - 3.4e-09 36.2 0.1 8.6e-09 34.9 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO14469.1 - 1.4e-07 31.3 0.0 2.9e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) 7tm_3 PF00003.17 ETO14470.1 - 0.093 12.0 0.1 0.11 11.8 0.1 1.1 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR IL8 PF00048.15 ETO14470.1 - 0.13 12.2 0.3 0.28 11.1 0.1 1.7 2 0 0 2 2 2 0 Small cytokines (intecrine/chemokine), interleukin-8 like CDC37_C PF08564.5 ETO14471.1 - 6.5e-19 67.6 0.3 6.5e-19 67.6 0.2 3.2 2 2 1 3 3 3 1 Cdc37 C terminal domain CDC37_M PF08565.6 ETO14471.1 - 6e-07 29.1 6.0 3.9e-06 26.4 3.7 2.6 1 1 0 1 1 1 1 Cdc37 Hsp90 binding domain DUF2360 PF10152.4 ETO14471.1 - 0.0038 17.5 0.6 0.0071 16.6 0.4 1.5 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) 7tm_2 PF00002.19 ETO14471.1 - 0.021 13.8 2.5 0.33 9.9 0.1 2.1 2 0 0 2 2 2 0 7 transmembrane receptor (Secretin family) PSD2 PF07624.6 ETO14471.1 - 0.038 13.6 0.7 0.26 10.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1585) Med3 PF11593.3 ETO14471.1 - 0.22 10.7 17.4 0.43 9.7 12.1 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal 7TM-7TMR_HD PF07698.6 ETO14471.1 - 0.22 10.9 1.9 6.4 6.1 0.2 2.1 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase Gly_transf_sug PF04488.10 ETO14472.1 - 1.6e-12 47.6 0.3 5e-12 46.1 0.2 1.9 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 ETO14472.1 - 0.0019 17.3 0.0 0.0046 16.1 0.0 1.7 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein DUF2986 PF11661.3 ETO14474.1 - 0.22 11.8 0.1 0.22 11.8 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2986) DUF4252 PF14060.1 ETO14474.1 - 5.6 6.5 10.6 0.08 12.4 1.2 2.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4252) G-alpha PF00503.15 ETO14476.1 - 3.6e-39 134.5 23.1 2.1e-31 108.9 4.8 4.5 2 2 1 3 3 3 3 G-protein alpha subunit AAA_11 PF13086.1 ETO14476.1 - 0.11 12.0 1.3 0.21 11.1 0.9 1.3 1 0 0 1 1 1 0 AAA domain Glyco_hydro_20 PF00728.17 ETO14478.1 - 7.5e-40 137.1 1.2 1.1e-20 74.0 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 ETO14479.1 - 3e-10 40.8 0.0 3.6e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like NYD-SP28_assoc PF14775.1 ETO14479.1 - 0.041 13.5 0.1 0.076 12.7 0.1 1.4 1 0 0 1 1 1 0 Sperm tail C-terminal domain SR-25 PF10500.4 ETO14479.1 - 0.32 10.4 4.5 0.38 10.1 3.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ABA_GPCR PF12430.3 ETO14480.1 - 0.11 11.5 6.9 0.028 13.5 1.0 2.0 2 0 0 2 2 2 0 Abscisic acid G-protein coupled receptor DUF2663 PF10864.3 ETO14480.1 - 0.16 12.1 3.9 0.37 11.0 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) Kelch_4 PF13418.1 ETO14481.1 - 0.0034 17.1 0.7 1.7 8.4 0.0 2.6 2 0 0 2 2 2 2 Galactose oxidase, central domain Arm PF00514.18 ETO14482.1 - 3.9e-16 58.2 3.9 0.032 14.0 0.0 6.6 6 0 0 6 6 6 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 ETO14482.1 - 0.00035 20.7 0.0 2.6 8.3 0.0 3.7 2 1 2 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 ETO14482.1 - 0.00083 19.7 0.0 7.6 7.1 0.0 3.6 3 0 0 3 3 3 2 HEAT-like repeat IBB PF01749.15 ETO14483.1 - 3.6e-05 23.8 3.4 6.7e-05 22.9 2.3 1.5 1 0 0 1 1 1 1 Importin beta binding domain Prominin PF05478.6 ETO14483.1 - 0.064 10.7 4.7 0.077 10.5 3.2 1.3 1 0 0 1 1 1 0 Prominin Enterotoxin_HS1 PF08090.6 ETO14483.1 - 0.12 12.1 1.4 0.26 11.0 0.9 1.5 1 0 0 1 1 1 0 Heat stable E.coli enterotoxin 1 RhoGAP PF00620.22 ETO14484.1 - 3.1e-32 111.3 0.1 4.4e-32 110.8 0.1 1.2 1 0 0 1 1 1 1 RhoGAP domain Pkinase PF00069.20 ETO14485.1 - 1.7e-34 119.1 0.0 2.7e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO14485.1 - 1.4e-12 47.2 0.0 2.3e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO14485.1 - 0.0064 15.4 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like CENP-W PF15510.1 ETO14485.1 - 0.73 9.8 2.7 1 9.3 0.7 2.1 2 0 0 2 2 2 0 Centromere kinetochore component W Peptidase_S10 PF00450.17 ETO14486.1 - 8.8e-41 140.4 1.1 8.8e-41 140.4 0.8 2.1 2 0 0 2 2 2 1 Serine carboxypeptidase Rhodanese PF00581.15 ETO14486.1 - 1.2e-07 32.0 0.2 9.9e-06 25.8 0.0 2.4 2 0 0 2 2 2 2 Rhodanese-like domain BBS2_C PF14782.1 ETO14490.1 - 1.6e-100 336.7 1.1 1.6e-99 333.4 0.8 1.9 1 1 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal DUF1583 PF07622.6 ETO14490.1 - 0.024 13.1 0.0 0.037 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1583) BBS2_N PF14781.1 ETO14491.1 - 7.6e-33 113.0 2.0 4.3e-32 110.6 0.1 2.8 2 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, N-terminal BBS2_Mid PF14783.1 ETO14491.1 - 1.6e-26 92.2 5.6 1.7e-24 85.7 1.3 3.6 2 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region BBS2_C PF14782.1 ETO14491.1 - 1.9e-08 33.3 0.1 2e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, C-terminal PQQ_2 PF13360.1 ETO14491.1 - 0.0016 17.9 0.3 0.012 15.1 0.1 2.1 2 0 0 2 2 2 1 PQQ-like domain VCBS PF13517.1 ETO14491.1 - 0.0073 16.6 3.2 0.24 11.7 0.3 2.8 2 1 0 2 2 2 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PHTB1_N PF14727.1 ETO14491.1 - 0.021 13.7 0.6 2.6 6.9 0.0 3.1 2 1 0 3 3 3 0 PTHB1 N-terminus BSD PF03909.12 ETO14492.1 - 0.0021 17.7 1.3 0.0035 17.0 0.0 2.1 2 0 0 2 2 2 1 BSD domain Daxx PF03344.10 ETO14492.1 - 0.31 9.4 19.0 0.37 9.2 13.2 1.1 1 0 0 1 1 1 0 Daxx Family Ndc1_Nup PF09531.5 ETO14492.1 - 1.3 7.3 8.5 1.5 7.1 5.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3537 PF12056.3 ETO14492.1 - 5.5 5.5 5.6 8 5.0 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) Macoilin PF09726.4 ETO14492.1 - 8.6 4.5 18.2 10 4.2 12.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Menin PF05053.8 ETO14492.1 - 9.1 4.3 15.0 13 3.8 10.4 1.2 1 0 0 1 1 1 0 Menin DUF3668 PF12416.3 ETO14493.1 - 1.3e-06 27.8 5.6 0.0022 17.2 0.2 2.7 3 0 0 3 3 3 2 Cep120 protein C2 PF00168.25 ETO14493.1 - 0.06 13.2 1.7 1.8 8.4 0.0 2.8 2 0 0 2 2 2 0 C2 domain ELM2 PF01448.19 ETO14494.1 - 0.01 16.4 1.4 0.013 16.1 0.0 2.0 2 0 0 2 2 2 0 ELM2 domain XRN_N PF03159.13 ETO14496.1 - 5.4e-73 245.2 0.2 5.4e-73 245.2 0.1 2.9 2 1 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus ANAPC15 PF15243.1 ETO14496.1 - 0.035 14.1 2.7 0.1 12.6 1.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 FMN_red PF03358.10 ETO14497.1 - 4e-10 39.3 0.0 5.9e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 ETO14497.1 - 0.00031 20.3 0.0 0.00041 19.9 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Zip PF02535.17 ETO14498.1 - 0.016 14.2 0.0 0.24 10.3 0.0 2.7 2 0 0 2 2 2 0 ZIP Zinc transporter DUF456 PF04306.8 ETO14498.1 - 0.057 13.4 8.2 0.64 10.0 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF456) DUF2244 PF10003.4 ETO14498.1 - 0.79 9.0 0.0 0.79 9.0 0.0 3.0 3 0 0 3 3 3 0 Integral membrane protein (DUF2244) Anoctamin PF04547.7 ETO14499.1 - 0.1 11.1 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel zf-RING_2 PF13639.1 ETO14499.1 - 2.8 7.8 11.4 0.59 10.0 4.8 2.1 2 0 0 2 2 2 0 Ring finger domain FF PF01846.14 ETO14500.1 - 0.052 13.5 1.8 1.5 8.8 0.0 2.7 3 0 0 3 3 3 0 FF domain IBR PF01485.16 ETO14500.1 - 0.28 11.0 10.8 0.29 11.0 0.9 2.3 1 1 1 2 2 2 0 IBR domain ADK_lid PF05191.9 ETO14500.1 - 0.54 9.9 4.8 8.6 6.1 0.8 3.3 3 0 0 3 3 3 0 Adenylate kinase, active site lid Ssl1 PF04056.9 ETO14501.1 - 1.6e-63 213.8 0.2 2.2e-63 213.3 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 ETO14501.1 - 6.6e-14 51.6 13.9 6.6e-14 51.6 9.6 2.6 2 0 0 2 2 2 1 TFIIH C1-like domain DZR PF12773.2 ETO14501.1 - 0.0051 16.6 15.3 0.066 13.0 4.3 2.8 1 1 1 2 2 2 1 Double zinc ribbon IBR PF01485.16 ETO14501.1 - 0.018 14.9 10.2 0.018 14.9 7.1 2.7 2 0 0 2 2 2 0 IBR domain ChlamPMP_M PF07548.6 ETO14501.1 - 0.027 14.2 0.1 0.046 13.4 0.1 1.4 1 0 0 1 1 1 0 Chlamydia polymorphic membrane protein middle domain YhjQ PF06564.7 ETO14501.1 - 0.074 12.3 0.3 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 YhjQ protein zf-RING_4 PF14570.1 ETO14501.1 - 6.4 6.4 21.2 0.85 9.2 7.9 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF99 PF01949.11 ETO14502.1 - 5e-05 22.5 0.0 5.8e-05 22.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF99 GTP_EFTU PF00009.22 ETO14503.1 - 2.3e-30 105.4 0.1 6.3e-30 104.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 ETO14503.1 - 1.8e-16 59.9 0.2 6e-16 58.2 0.0 2.0 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 ETO14503.1 - 3.1e-10 40.0 7.1 3.8e-06 26.9 0.0 3.6 3 0 0 3 3 3 2 Elongation factor Tu domain 2 AAA_22 PF13401.1 ETO14503.1 - 0.00057 20.0 0.0 0.0017 18.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain GTP_EFTU_D4 PF14578.1 ETO14503.1 - 0.00071 19.1 0.4 0.0029 17.2 0.3 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 ETO14503.1 - 0.00074 20.0 0.0 0.0024 18.3 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein ATP_bind_1 PF03029.12 ETO14503.1 - 0.022 14.2 0.0 0.057 12.9 0.0 1.8 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Pkinase PF00069.20 ETO14504.1 - 3.4e-06 26.3 0.9 8.8e-06 25.0 0.7 1.6 1 1 0 1 1 1 1 Protein kinase domain RP-C_C PF11800.3 ETO14504.1 - 1.7 8.2 7.5 3.3 7.3 5.2 1.5 1 0 0 1 1 1 0 Replication protein C C-terminal region Pkinase PF00069.20 ETO14505.1 - 5.3e-19 68.3 0.1 6.1e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO14505.1 - 0.0074 15.3 0.0 0.009 15.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2207 PF09972.4 ETO14505.1 - 0.054 12.0 4.3 0.063 11.8 3.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) P12 PF12669.2 ETO14505.1 - 9.9 6.4 7.0 18 5.6 4.4 1.9 2 0 0 2 2 2 0 Virus attachment protein p12 family EAP30 PF04157.11 ETO14507.1 - 3.4e-47 160.4 1.7 5.1e-47 159.9 1.2 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family DUF3376 PF11856.3 ETO14507.1 - 0.02 14.2 0.1 0.028 13.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3376) FlaC_arch PF05377.6 ETO14508.1 - 0.061 13.2 0.3 0.061 13.2 0.2 11.0 10 2 2 12 12 12 0 Flagella accessory protein C (FlaC) Ribosomal_S7e PF01251.13 ETO14509.1 - 3.3e-51 173.4 4.9 6.8e-48 162.6 2.2 2.9 2 0 0 2 2 2 2 Ribosomal protein S7e TFIID-18kDa PF02269.11 ETO14509.1 - 3e-17 62.2 0.8 1.1e-16 60.4 0.2 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Longin PF13774.1 ETO14509.1 - 0.0036 16.8 0.5 0.011 15.2 0.3 1.8 1 0 0 1 1 1 1 Regulated-SNARE-like domain MIP-T3 PF10243.4 ETO14509.1 - 0.33 9.3 28.8 0.53 8.7 20.0 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2201_N PF13203.1 ETO14509.1 - 9.6 5.2 13.8 13 4.8 9.1 1.4 2 0 0 2 2 2 0 Putative metallopeptidase domain Sulfotransfer_1 PF00685.22 ETO14510.1 - 0.0002 20.7 2.0 0.0031 16.8 1.3 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.9 ETO14510.1 - 0.1 12.2 1.7 0.085 12.5 0.2 1.6 2 0 0 2 2 2 0 Sulfotransferase family Sulfotransfer_3 PF13469.1 ETO14510.1 - 0.13 13.1 0.7 0.21 12.5 0.4 1.4 1 1 0 1 1 1 0 Sulfotransferase family DUF1077 PF06417.7 ETO14511.1 - 1.2e-36 124.8 2.1 2.2e-36 123.9 1.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) DUF4252 PF14060.1 ETO14511.1 - 0.051 13.1 1.4 0.13 11.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4252) HlyIII PF03006.15 ETO14512.1 - 2.6e-07 30.2 21.5 3.3e-07 29.9 14.9 1.2 1 0 0 1 1 1 1 Haemolysin-III related Tmemb_18A PF09771.4 ETO14512.1 - 2 8.4 5.9 3.5 7.6 4.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 188 Pkinase PF00069.20 ETO14513.1 - 1.3e-37 129.3 2.9 1.5e-32 112.7 0.2 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO14513.1 - 7.5e-18 64.5 0.2 1.1e-16 60.6 0.1 2.5 2 0 0 2 2 2 1 Protein tyrosine kinase MRF_C2 PF13888.1 ETO14513.1 - 0.033 13.9 3.7 0.11 12.2 2.1 2.3 2 1 1 3 3 3 0 Myelin gene regulatory factor C-terminal domain 2 PI3Ka PF00613.15 ETO14516.1 - 2e-39 134.7 3.0 3.5e-39 133.8 2.1 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 ETO14516.1 - 6.3e-34 117.4 0.7 6.3e-34 117.4 0.5 2.2 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase HEAT_2 PF13646.1 ETO14516.1 - 0.023 14.9 0.0 0.055 13.7 0.0 1.5 1 0 0 1 1 1 0 HEAT repeats FimP PF09766.4 ETO14516.1 - 9.1 5.2 17.6 26 3.7 12.2 1.8 1 1 0 1 1 1 0 Fms-interacting protein Peptidase_S49_N PF08496.5 ETO14517.1 - 0.11 12.2 21.4 0.13 12.0 14.8 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1764 PF08576.5 ETO14517.1 - 0.2 12.4 19.5 0.23 12.2 13.5 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF3807 PF12720.2 ETO14517.1 - 0.26 11.4 14.4 0.28 11.3 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) PARP PF00644.15 ETO14517.1 - 0.27 10.6 6.9 0.33 10.3 4.8 1.1 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain DDHD PF02862.12 ETO14517.1 - 0.28 10.9 8.9 0.28 10.9 6.2 1.0 1 0 0 1 1 1 0 DDHD domain AAA_13 PF13166.1 ETO14517.1 - 0.36 9.2 20.5 0.4 9.0 14.2 1.0 1 0 0 1 1 1 0 AAA domain Vfa1 PF08432.5 ETO14517.1 - 0.5 10.3 23.4 0.54 10.2 16.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RR_TM4-6 PF06459.7 ETO14517.1 - 0.79 9.5 11.5 0.76 9.6 7.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.7 ETO14517.1 - 1.1 9.1 20.7 1.3 8.9 14.3 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Rtf2 PF04641.7 ETO14517.1 - 1.2 8.2 20.1 1.5 7.9 13.9 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger LicD PF04991.8 ETO14517.1 - 1.5 8.8 13.3 1.7 8.6 9.2 1.1 1 0 0 1 1 1 0 LicD family Dala_Dala_lig_N PF01820.16 ETO14517.1 - 1.6 9.0 5.1 1.9 8.8 3.5 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus PH_4 PF15404.1 ETO14517.1 - 1.8 8.0 12.8 2.2 7.7 8.9 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain DUF262 PF03235.9 ETO14517.1 - 2 8.3 8.4 2.1 8.2 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 PEX11 PF05648.9 ETO14517.1 - 2.5 7.3 8.5 2.7 7.1 5.9 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) PRTP PF01366.13 ETO14517.1 - 2.5 5.9 8.6 2.6 5.9 5.9 1.0 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Band_3_cyto PF07565.8 ETO14517.1 - 2.8 7.3 6.1 2.8 7.3 4.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FCP1_C PF09309.5 ETO14517.1 - 2.9 7.1 10.6 3.1 7.0 7.3 1.1 1 0 0 1 1 1 0 FCP1, C-terminal PcfK PF14058.1 ETO14517.1 - 3 7.9 23.0 3.5 7.7 16.0 1.1 1 0 0 1 1 1 0 PcfK-like protein DUF3340 PF11818.3 ETO14517.1 - 3.1 7.7 14.8 3.5 7.5 10.3 1.1 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) EIIBC-GUT_N PF03612.9 ETO14517.1 - 3.5 7.2 8.4 4 7.0 5.8 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Casc1 PF12366.3 ETO14517.1 - 3.5 7.0 15.6 3.8 6.9 10.8 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 Rot1 PF10681.4 ETO14517.1 - 3.5 6.8 5.1 3.9 6.7 3.5 1.3 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal RNA_pol_Rpc4 PF05132.9 ETO14517.1 - 3.8 7.5 11.0 4.6 7.2 7.6 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF3464 PF11947.3 ETO14517.1 - 4 6.8 14.2 4.7 6.6 9.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF2828 PF11443.3 ETO14517.1 - 4.4 5.3 12.6 4.6 5.3 8.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Glyco_transf_15 PF01793.11 ETO14517.1 - 4.5 6.1 9.8 4.8 6.0 6.8 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase RNase_H2-Ydr279 PF09468.5 ETO14517.1 - 4.8 6.2 30.6 5.5 6.0 21.2 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Folate_carrier PF01770.13 ETO14517.1 - 5 5.5 5.8 5.1 5.4 4.0 1.0 1 0 0 1 1 1 0 Reduced folate carrier Cnd1_N PF12922.2 ETO14517.1 - 5 6.7 10.3 6.3 6.4 7.1 1.2 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term YqfQ PF14181.1 ETO14517.1 - 5.8 6.9 18.4 6.5 6.7 12.8 1.1 1 0 0 1 1 1 0 YqfQ-like protein NPR3 PF03666.8 ETO14517.1 - 6.4 5.1 12.5 6.6 5.1 8.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RNA_pol_Rpb1_5 PF04998.12 ETO14517.1 - 6.6 5.9 11.8 6.4 5.9 8.2 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 YL1 PF05764.8 ETO14517.1 - 7.3 6.1 27.2 8 5.9 18.8 1.1 1 0 0 1 1 1 0 YL1 nuclear protein LMBR1 PF04791.11 ETO14517.1 - 7.7 4.9 6.3 7.3 5.0 4.4 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Siah-Interact_N PF09032.6 ETO14517.1 - 8.2 6.5 19.3 13 5.9 13.4 1.3 1 0 0 1 1 1 0 Siah interacting protein, N terminal SspB PF04386.8 ETO14517.1 - 9.8 5.7 10.6 13 5.3 7.4 1.2 1 0 0 1 1 1 0 Stringent starvation protein B zf-C4H2 PF10146.4 ETO14518.1 - 1.7 8.6 7.5 0.33 10.9 0.3 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein Zip PF02535.17 ETO14519.1 - 0.092 11.7 1.3 0.15 10.9 0.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Pox_Ag35 PF03286.9 ETO14519.1 - 0.81 9.1 8.5 1.5 8.3 5.9 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein GalKase_gal_bdg PF10509.4 ETO14520.1 - 5.4e-22 76.8 0.0 9.5e-22 76.0 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 ETO14520.1 - 1.4e-10 41.0 0.1 3.4e-10 39.8 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 ETO14520.1 - 1e-07 32.0 0.0 3.1e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal DUF3040 PF11239.3 ETO14520.1 - 2.6 8.1 4.5 3.5 7.7 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) UPF0242 PF06785.6 ETO14522.1 - 0.0075 15.0 0.5 0.0087 14.7 0.3 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) DUF3959 PF13105.1 ETO14522.1 - 1.6 7.9 7.7 1.1 8.5 4.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3959) FHIPEP PF00771.15 ETO14523.1 - 0.41 8.9 2.5 0.54 8.5 1.8 1.2 1 0 0 1 1 1 0 FHIPEP family DEP PF00610.16 ETO14524.1 - 1.8e-09 37.2 0.8 2.9e-08 33.3 0.5 2.4 1 1 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CAP_GLY PF01302.20 ETO14525.1 - 1.1e-14 53.8 0.6 8.5e-14 51.0 0.4 2.1 1 1 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 ETO14525.1 - 6.5e-14 51.1 19.4 0.00016 21.2 2.2 5.4 3 2 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO14525.1 - 6.3e-09 35.4 11.7 0.037 13.7 0.3 4.8 4 0 0 4 4 4 4 Leucine rich repeat Ubiquitin_2 PF14560.1 ETO14525.1 - 2.2e-07 31.0 0.1 7.4e-07 29.3 0.1 1.9 1 0 0 1 1 1 1 Ubiquitin-like domain LRR_6 PF13516.1 ETO14525.1 - 2.9e-05 23.6 11.1 0.044 13.8 0.0 5.9 6 0 0 6 6 6 1 Leucine Rich repeat LRR_1 PF00560.28 ETO14525.1 - 8.2e-05 22.1 21.0 1.3 9.3 0.0 7.0 5 2 1 6 6 6 3 Leucine Rich Repeat LRR_9 PF14580.1 ETO14525.1 - 0.0012 18.4 0.2 0.059 12.9 0.0 3.0 3 0 0 3 3 3 1 Leucine-rich repeat LRR_7 PF13504.1 ETO14525.1 - 0.012 15.6 10.3 37 5.1 0.2 6.2 6 0 0 6 6 6 0 Leucine rich repeat CAF-1_p150 PF11600.3 ETO14526.1 - 6.1 6.1 53.4 0.23 10.8 23.3 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal WHIM3 PF15614.1 ETO14526.1 - 8.6 6.2 9.6 0.6 9.9 2.5 2.2 3 0 0 3 3 3 0 WSTF, HB1, Itc1p, MBD9 motif 3 fn3 PF00041.16 ETO14527.1 - 3.8e-14 52.5 0.0 0.019 15.0 0.0 4.4 4 0 0 4 4 4 4 Fibronectin type III domain Neur_chan_memb PF02932.11 ETO14527.1 - 0.29 10.9 4.9 0.48 10.2 3.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SRP-alpha_N PF04086.8 ETO14527.1 - 6.4 6.0 11.5 10 5.3 8.0 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PDZ PF00595.19 ETO14528.1 - 5.7e-06 26.4 0.3 1.5e-05 25.0 0.2 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 ETO14528.1 - 0.0021 17.9 0.1 0.0046 16.8 0.1 1.5 1 0 0 1 1 1 1 PDZ domain 2OG-FeII_Oxy_2 PF13532.1 ETO14529.1 - 1e-11 45.0 0.0 1.5e-11 44.4 0.0 1.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 ETO14529.1 - 0.02 15.1 0.0 0.043 14.1 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DOG1 PF14144.1 ETO14530.1 - 0.018 15.1 0.1 0.44 10.6 0.0 3.0 2 0 0 2 2 2 0 Seed dormancy control RhoGEF PF00621.15 ETO14531.1 - 1.1e-16 61.2 2.2 1.6e-16 60.7 1.6 1.2 1 0 0 1 1 1 1 RhoGEF domain PBP1_TM PF14812.1 ETO14533.1 - 2.4 8.5 8.9 7 7.0 4.4 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pkinase PF00069.20 ETO14534.1 - 2.9e-08 33.1 0.0 4.4e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain CCDC155 PF14662.1 ETO14535.1 - 0.00099 18.7 7.2 0.0074 15.8 3.2 2.1 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 Microtub_assoc PF07989.6 ETO14535.1 - 0.0076 16.0 1.9 0.0076 16.0 1.3 2.7 3 0 0 3 3 3 1 Microtubule associated KLRAQ PF10205.4 ETO14535.1 - 0.0082 16.1 3.1 0.0082 16.1 2.1 1.8 2 0 0 2 2 2 1 Predicted coiled-coil domain-containing protein Sec2p PF06428.6 ETO14535.1 - 0.0098 15.7 2.0 0.0098 15.7 1.4 2.0 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p ADIP PF11559.3 ETO14535.1 - 0.012 15.5 3.7 0.012 15.5 2.5 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF496 PF04363.7 ETO14535.1 - 0.043 13.6 1.2 0.043 13.6 0.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF496) AAA_27 PF13514.1 ETO14535.1 - 0.048 11.3 4.3 0.058 11.0 3.0 1.0 1 0 0 1 1 1 0 AAA domain Fmp27_WPPW PF10359.4 ETO14535.1 - 0.076 11.4 5.8 0.083 11.2 4.0 1.3 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Cep57_CLD_2 PF14197.1 ETO14535.1 - 0.085 12.8 1.0 0.085 12.8 0.7 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 V_ATPase_I PF01496.14 ETO14535.1 - 0.089 10.6 4.8 0.1 10.4 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tropomyosin_1 PF12718.2 ETO14535.1 - 0.099 12.4 13.0 0.032 14.0 4.9 2.2 2 0 0 2 2 2 0 Tropomyosin like Mod_r PF07200.8 ETO14535.1 - 0.16 11.8 8.0 0.03 14.2 2.3 1.9 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein ATG16 PF08614.6 ETO14535.1 - 0.38 10.5 8.9 2.3 7.9 0.4 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Mnd1 PF03962.10 ETO14535.1 - 0.47 10.0 6.9 0.15 11.6 2.9 1.6 1 1 0 1 1 1 0 Mnd1 family Cep57_CLD PF14073.1 ETO14535.1 - 0.5 10.1 7.0 0.73 9.6 2.0 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 TMF_DNA_bd PF12329.3 ETO14535.1 - 0.51 10.1 14.0 1.5 8.6 3.9 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIVA PF05103.8 ETO14535.1 - 0.62 10.1 7.2 1.7 8.7 4.6 1.9 1 1 1 2 2 2 0 DivIVA protein Tropomyosin PF00261.15 ETO14535.1 - 0.63 9.0 11.4 0.088 11.8 3.2 2.0 2 0 0 2 2 2 0 Tropomyosin IncA PF04156.9 ETO14535.1 - 0.77 9.3 10.1 17 4.9 7.0 2.2 1 1 0 1 1 1 0 IncA protein DUF972 PF06156.8 ETO14535.1 - 0.85 9.9 7.1 0.97 9.8 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Lzipper-MIP1 PF14389.1 ETO14535.1 - 0.9 9.6 8.8 0.059 13.4 1.1 2.5 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Fib_alpha PF08702.5 ETO14535.1 - 1.3 9.1 5.6 4.5 7.3 3.7 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family GAS PF13851.1 ETO14535.1 - 1.7 7.7 12.5 0.5 9.5 4.5 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Snapin_Pallidin PF14712.1 ETO14535.1 - 1.7 8.9 8.5 0.32 11.3 1.9 2.2 2 0 0 2 2 2 0 Snapin/Pallidin DUF904 PF06005.7 ETO14535.1 - 2.3 8.5 16.3 4.5 7.6 6.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF904) APG6 PF04111.7 ETO14535.1 - 6.1 5.7 10.3 0.86 8.5 3.7 1.8 2 0 0 2 2 2 0 Autophagy protein Apg6 Cut12 PF11500.3 ETO14535.1 - 7.6 6.2 9.4 0.85 9.3 2.1 2.2 2 1 0 2 2 2 0 Spindle pole body formation-associated protein Rabaptin PF03528.10 ETO14535.1 - 8.5 6.3 10.6 2 8.3 3.8 2.3 2 1 0 2 2 2 0 Rabaptin bZIP_1 PF00170.16 ETO14535.1 - 9.5 6.2 10.9 5.5 7.0 0.4 3.0 2 1 0 3 3 3 0 bZIP transcription factor HECT PF00632.20 ETO14536.1 - 9.6e-63 212.2 0.2 1.5e-62 211.6 0.2 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 ETO14536.1 - 4.5e-13 49.3 1.6 8.7e-13 48.4 0.8 1.7 2 0 0 2 2 2 1 SPRY domain Sporozoite_P67 PF05642.6 ETO14537.1 - 0.011 13.6 11.0 0.013 13.4 2.3 2.0 1 1 1 2 2 2 0 Sporozoite P67 surface antigen DUF4175 PF13779.1 ETO14537.1 - 0.061 11.0 6.3 0.069 10.8 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) M_domain PF12938.2 ETO14537.1 - 0.64 9.7 13.2 0.54 10.0 8.3 1.4 1 1 0 1 1 1 0 M domain of GW182 DUF3807 PF12720.2 ETO14537.1 - 0.7 10.0 8.7 0.075 13.1 2.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3807) Nop25 PF09805.4 ETO14537.1 - 1.6 8.7 8.8 0.079 13.0 0.9 2.1 1 1 1 2 2 2 0 Nucleolar protein 12 (25kDa) DUF3439 PF11921.3 ETO14537.1 - 5.6 6.7 12.8 10 5.8 8.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) MT PF12777.2 ETO14538.1 - 3.2e-10 39.3 10.5 6.6e-10 38.2 7.3 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor DUF1421 PF07223.6 ETO14538.1 - 0.016 15.0 1.3 0.016 15.0 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1421) DUF4654 PF15547.1 ETO14538.1 - 0.025 14.9 1.0 0.74 10.1 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4654) WD40 PF00400.27 ETO14539.1 - 6.8e-58 190.6 22.4 1e-09 37.8 0.1 7.1 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO14539.1 - 3.3e-13 48.6 6.9 0.01 13.9 0.0 5.8 2 2 2 5 5 5 5 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO14539.1 - 0.55 10.4 10.9 51 4.2 0.0 5.4 5 0 0 5 5 5 0 Kelch motif WD40 PF00400.27 ETO14540.1 - 7e-54 177.9 29.1 9.6e-12 44.3 0.6 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO14540.1 - 1.7e-09 36.3 4.9 0.0021 16.2 2.4 3.9 2 2 1 3 3 3 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO14540.1 - 3.3e-05 23.6 1.2 0.03 14.1 0.0 4.2 3 2 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Gti1_Pac2 PF09729.4 ETO14541.1 - 0.017 14.9 0.3 2.9 7.7 0.0 2.7 2 0 0 2 2 2 0 Gti1/Pac2 family DUF4094 PF13334.1 ETO14541.1 - 0.24 11.8 0.1 0.24 11.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) WD40 PF00400.27 ETO14542.1 - 1.3e-71 234.1 19.2 1.1e-12 47.3 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO14542.1 - 4.6e-12 44.8 9.2 0.01 13.9 0.0 5.4 1 1 4 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO14542.1 - 9.4e-07 27.9 13.8 0.21 10.2 1.2 5.8 2 1 1 4 4 4 4 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO14542.1 - 7e-06 24.5 1.3 0.0024 16.2 0.0 3.3 1 1 3 4 4 4 3 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO14542.1 - 4e-05 23.1 1.0 0.0015 17.9 0.6 2.6 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.16 ETO14542.1 - 4.1e-05 22.8 0.0 9.4 5.9 0.0 4.7 5 0 0 5 5 5 1 PQQ enzyme repeat Resistin PF06954.6 ETO14542.1 - 0.0076 16.4 3.9 20 5.5 0.0 4.4 3 1 2 5 5 5 1 Resistin Srg PF02118.16 ETO14543.1 - 0.02 14.3 0.1 0.03 13.7 0.1 1.2 1 0 0 1 1 1 0 Srg family chemoreceptor Rrp15p PF07890.7 ETO14545.1 - 0.0066 16.4 0.5 0.014 15.4 0.3 1.5 1 0 0 1 1 1 1 Rrp15p DUF809 PF05663.6 ETO14545.1 - 0.023 14.6 7.3 0.026 14.4 0.5 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF809) RGS PF00615.14 ETO14545.1 - 0.05 13.6 3.2 0.7 10.0 2.2 2.6 1 1 0 1 1 1 0 Regulator of G protein signaling domain VID27 PF08553.5 ETO14545.1 - 0.1 10.8 4.8 0.14 10.3 3.4 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein FAM176 PF14851.1 ETO14545.1 - 0.15 11.7 4.3 7.4 6.2 2.0 2.5 2 0 0 2 2 2 0 FAM176 family Nucleoplasmin PF03066.10 ETO14545.1 - 0.17 11.3 5.1 0.34 10.4 3.5 1.4 1 0 0 1 1 1 0 Nucleoplasmin DUF3824 PF12868.2 ETO14545.1 - 0.63 10.9 2.9 1.1 10.1 2.0 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF3682 PF12446.3 ETO14545.1 - 5.4 7.3 8.6 9.6 6.5 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Ras PF00071.17 ETO14546.1 - 3.2e-23 81.9 0.2 5.1e-23 81.2 0.1 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO14546.1 - 8.4e-07 29.5 0.0 1.7e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO14546.1 - 0.011 15.0 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family DUF1777 PF08648.7 ETO14547.1 - 0.00023 20.9 11.3 0.0049 16.6 8.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) Transformer PF06495.6 ETO14547.1 - 0.0037 17.1 15.2 0.0055 16.6 10.5 1.2 1 0 0 1 1 1 1 Fruit fly transformer protein Mating_C PF12737.2 ETO14547.1 - 0.14 11.0 10.5 0.18 10.6 7.3 1.1 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 Suf PF05843.9 ETO14547.1 - 0.16 11.6 0.9 0.2 11.3 0.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Macoilin PF09726.4 ETO14547.1 - 2.8 6.0 8.2 3.6 5.7 5.7 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF1509 PF07420.6 ETO14547.1 - 6.8 5.8 14.0 12 5.0 9.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) SelP_N PF04592.9 ETO14548.1 - 4.1e-05 23.0 13.0 5.4e-05 22.6 9.0 1.1 1 0 0 1 1 1 1 Selenoprotein P, N terminal region Atrophin-1 PF03154.10 ETO14548.1 - 0.00077 17.7 13.0 0.00097 17.4 9.0 1.1 1 0 0 1 1 1 1 Atrophin-1 family Zip PF02535.17 ETO14548.1 - 0.0051 15.8 9.3 0.0057 15.7 6.5 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Vfa1 PF08432.5 ETO14548.1 - 0.035 14.1 20.5 0.038 14.0 14.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RNA_pol_Rpc4 PF05132.9 ETO14548.1 - 0.04 13.9 8.4 0.06 13.3 5.8 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 OATP PF03137.15 ETO14548.1 - 0.061 11.3 2.6 0.061 11.3 1.8 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Ycf1 PF05758.7 ETO14548.1 - 0.066 10.9 10.3 0.067 10.9 7.1 1.0 1 0 0 1 1 1 0 Ycf1 MIP-T3 PF10243.4 ETO14548.1 - 0.073 11.5 22.8 0.085 11.3 15.8 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Folate_carrier PF01770.13 ETO14548.1 - 0.095 11.1 1.6 0.1 11.0 1.1 1.2 1 0 0 1 1 1 0 Reduced folate carrier Trypan_PARP PF05887.6 ETO14548.1 - 0.1 12.4 8.8 0.14 11.9 6.1 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Tim54 PF11711.3 ETO14548.1 - 0.1 11.1 7.8 0.11 11.0 5.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FAM176 PF14851.1 ETO14548.1 - 0.11 12.1 8.8 0.14 11.8 6.1 1.2 1 0 0 1 1 1 0 FAM176 family AAT PF03417.11 ETO14548.1 - 0.13 11.7 3.7 0.16 11.4 2.5 1.1 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Paf1 PF03985.8 ETO14548.1 - 0.13 10.9 15.5 0.16 10.6 10.7 1.1 1 0 0 1 1 1 0 Paf1 GOLD_2 PF13897.1 ETO14548.1 - 0.14 12.4 2.3 0.19 11.9 1.6 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking DUF1510 PF07423.6 ETO14548.1 - 0.21 10.9 17.6 0.26 10.6 12.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pox_Ag35 PF03286.9 ETO14548.1 - 0.24 10.9 16.4 0.29 10.6 11.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TRAP_alpha PF03896.11 ETO14548.1 - 0.25 10.2 4.4 0.3 10.0 3.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2413 PF10310.4 ETO14548.1 - 0.3 9.8 11.1 0.32 9.7 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DDHD PF02862.12 ETO14548.1 - 0.5 10.1 8.4 0.55 9.9 5.8 1.2 1 0 0 1 1 1 0 DDHD domain NPR3 PF03666.8 ETO14548.1 - 0.61 8.5 11.1 0.75 8.2 7.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Nucleoside_tran PF01733.13 ETO14548.1 - 0.64 9.1 2.6 0.87 8.6 1.8 1.3 1 0 0 1 1 1 0 Nucleoside transporter U79_P34 PF03064.11 ETO14548.1 - 0.74 9.2 15.1 0.87 9.0 10.5 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CDC45 PF02724.9 ETO14548.1 - 0.81 7.6 15.9 0.89 7.5 11.0 1.0 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.7 ETO14548.1 - 0.82 9.5 12.1 1 9.2 8.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Rota_VP2 PF05087.7 ETO14548.1 - 0.92 7.3 10.4 0.98 7.2 7.2 1.0 1 0 0 1 1 1 0 Rotavirus VP2 protein Chlam_OMP3 PF03503.8 ETO14548.1 - 1 9.6 4.1 0.3 11.3 0.5 1.9 2 0 0 2 2 1 0 Chlamydia cysteine-rich outer membrane protein 3 RRN3 PF05327.6 ETO14548.1 - 1 7.3 8.3 1.2 7.1 5.8 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PH_4 PF15404.1 ETO14548.1 - 1.2 8.6 11.4 1.1 8.7 7.2 1.4 1 1 0 1 1 1 0 Pleckstrin homology domain NARP1 PF12569.3 ETO14548.1 - 1.2 7.8 14.1 1.3 7.6 9.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Cellulose_synt PF03552.9 ETO14548.1 - 1.2 7.3 5.8 1.2 7.3 4.0 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF2215 PF10225.4 ETO14548.1 - 2 7.7 3.5 2.2 7.6 2.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Peptidase_S49_N PF08496.5 ETO14548.1 - 2.1 8.0 12.1 3 7.6 8.4 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Paramyxo_ncap PF00973.14 ETO14548.1 - 2.4 6.7 8.6 2.7 6.6 6.0 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Dsh_C PF12316.3 ETO14548.1 - 2.5 8.1 8.0 3.3 7.7 5.5 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Neur_chan_memb PF02932.11 ETO14548.1 - 3.3 7.5 12.5 3.7 7.3 8.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3464 PF11947.3 ETO14548.1 - 6.8 6.1 8.9 9.9 5.6 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Prog_receptor PF02161.10 ETO14548.1 - 8.4 5.0 7.4 9.5 4.9 5.1 1.1 1 0 0 1 1 1 0 Progesterone receptor DUF4337 PF14235.1 ETO14548.1 - 8.9 6.1 10.0 13 5.6 6.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Bap31 PF05529.7 ETO14548.1 - 9.4 5.6 10.5 13 5.1 7.3 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like eIF_4EBP PF05456.6 ETO14548.1 - 9.7 5.9 8.9 16 5.2 6.2 1.5 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DUF3987 PF13148.1 ETO14548.1 - 9.8 4.6 10.0 12 4.2 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) WD40 PF00400.27 ETO14549.1 - 3.5e-179 575.1 64.4 9.4e-14 50.6 0.1 15.0 15 0 0 15 15 15 14 WD domain, G-beta repeat NACHT PF05729.7 ETO14549.1 - 1.8e-10 40.7 0.0 3.3e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Gmad1 PF10647.4 ETO14549.1 - 1e-08 34.8 4.2 0.0086 15.4 0.1 5.5 2 2 1 4 4 4 3 Lipoprotein LpqB beta-propeller domain AAA_18 PF13238.1 ETO14549.1 - 0.00012 22.4 0.2 0.00012 22.4 0.1 3.5 4 0 0 4 4 3 1 AAA domain AAA_17 PF13207.1 ETO14549.1 - 0.0021 18.8 0.5 0.01 16.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETO14549.1 - 0.0037 17.4 0.0 0.015 15.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain DUF617 PF04759.8 ETO14549.1 - 0.018 14.6 0.7 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF617 UPF0079 PF02367.12 ETO14549.1 - 0.024 14.2 0.3 0.078 12.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Pentapeptide PF00805.17 ETO14549.1 - 0.039 13.2 0.1 0.086 12.1 0.1 1.6 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) CUE PF02845.11 ETO14549.1 - 0.15 11.5 1.4 13 5.3 0.1 2.9 2 0 0 2 2 2 0 CUE domain Resistin PF06954.6 ETO14549.1 - 1.5 9.1 8.7 96 3.3 0.3 5.5 4 1 1 5 5 5 0 Resistin PD40 PF07676.7 ETO14549.1 - 3.2 7.5 25.8 40 4.0 0.0 9.3 11 0 0 11 11 11 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 ETO14550.1 - 7.8e-70 228.4 15.6 7.6e-12 44.6 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO14550.1 - 8.8e-06 24.2 0.3 0.068 11.4 0.0 3.0 2 1 1 3 3 3 2 Cytochrome D1 heme domain DPPIV_N PF00930.16 ETO14550.1 - 0.0032 16.1 1.0 7.5 5.0 0.0 3.9 2 1 3 5 5 5 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF4221 PF13970.1 ETO14550.1 - 0.0033 16.7 2.8 0.077 12.2 0.0 3.2 1 1 2 3 3 3 1 Domain of unknown function (DUF4221) DUF1258 PF06869.7 ETO14550.1 - 0.032 13.3 3.2 6 5.8 0.0 3.7 1 1 4 5 5 5 0 Protein of unknown function (DUF1258) PUF PF00806.14 ETO14552.1 - 2.2e-22 77.1 1.9 4e-06 26.0 0.0 6.1 6 0 0 6 6 6 4 Pumilio-family RNA binding repeat DUF4013 PF13197.1 ETO14554.1 - 0.17 11.2 9.1 0.012 15.0 2.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4013) FAD_binding_1 PF00667.15 ETO14557.1 - 6.1e-39 133.7 0.0 1.1e-38 132.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 ETO14557.1 - 4.3e-29 101.3 2.0 1.2e-28 99.8 0.8 2.2 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 ETO14557.1 - 1.2e-14 54.7 0.0 4.5e-14 52.9 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 ETO14557.1 - 0.027 14.3 0.3 4.5 7.1 0.0 3.1 3 0 0 3 3 3 0 Ferric reductase NAD binding domain DUF4199 PF13858.1 ETO14558.1 - 0.0011 18.9 0.0 0.0012 18.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) SpoIIIAH PF12685.2 ETO14558.1 - 0.0021 17.5 0.0 0.0024 17.4 0.0 1.0 1 0 0 1 1 1 1 SpoIIIAH-like protein Nucleoside_tran PF01733.13 ETO14558.1 - 0.011 14.8 0.1 0.012 14.7 0.1 1.0 1 0 0 1 1 1 0 Nucleoside transporter DUF4363 PF14276.1 ETO14558.1 - 0.023 14.3 0.1 0.028 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) DUF788 PF05620.6 ETO14558.1 - 0.028 14.3 1.6 0.036 13.9 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF788) DUF1682 PF07946.9 ETO14558.1 - 0.066 12.0 7.1 0.074 11.8 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) RNase_H2-Ydr279 PF09468.5 ETO14558.1 - 0.077 12.1 4.4 0.084 12.0 3.0 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Bap31 PF05529.7 ETO14558.1 - 0.5 9.8 2.3 0.53 9.7 1.6 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like YqfQ PF14181.1 ETO14558.1 - 0.92 9.5 7.3 0.97 9.4 5.1 1.0 1 0 0 1 1 1 0 YqfQ-like protein DUF2502 PF10697.4 ETO14558.1 - 2 8.5 7.0 2.3 8.3 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2502) Atrophin-1 PF03154.10 ETO14558.1 - 3.4 5.6 10.7 3.4 5.6 7.4 1.0 1 0 0 1 1 1 0 Atrophin-1 family 7tm_3 PF00003.17 ETO14560.1 - 4.6e-26 91.6 21.0 4.6e-26 91.6 14.6 2.1 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR Kelch_4 PF13418.1 ETO14560.1 - 5.9e-09 35.5 4.6 0.00091 18.9 0.2 4.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO14560.1 - 1.6e-06 28.0 3.1 0.12 12.5 0.0 4.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO14560.1 - 3.5e-05 23.6 9.4 0.13 12.2 0.1 5.4 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 ETO14560.1 - 0.0014 18.7 10.1 17 5.8 0.0 7.1 6 0 0 6 6 6 1 Kelch motif Humanin PF15040.1 ETO14560.1 - 1 8.6 2.6 2.3 7.5 1.8 1.5 1 0 0 1 1 1 0 Humanin family PDEase_I PF00233.14 ETO14561.1 - 2.2e-46 158.5 8.3 2.4e-45 155.1 5.8 2.3 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.21 ETO14561.1 - 7.1e-08 32.7 0.0 1.8e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 GAF domain GAF_3 PF13492.1 ETO14561.1 - 5e-07 29.8 0.4 3.6e-06 27.1 0.3 2.3 1 1 0 1 1 1 1 GAF domain GAF_2 PF13185.1 ETO14561.1 - 8.2e-07 29.6 0.0 2.3e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 GAF domain Secretin_N_2 PF07655.8 ETO14561.1 - 0.074 13.4 28.6 0.059 13.7 10.0 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain OATP PF03137.15 ETO14561.1 - 0.12 10.3 0.1 0.23 9.4 0.0 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Pex14_N PF04695.8 ETO14561.1 - 0.68 9.9 13.9 2.1 8.4 0.2 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region YajC PF02699.10 ETO14562.1 - 0.069 12.8 0.8 2.4 7.8 0.1 2.6 2 0 0 2 2 2 0 Preprotein translocase subunit DUF2489 PF10675.4 ETO14562.1 - 1.5 8.4 4.9 4.3 7.0 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) Hist_deacetyl PF00850.14 ETO14563.1 - 1.3e-63 215.1 0.6 1.3e-63 215.1 0.4 1.7 2 0 0 2 2 2 1 Histone deacetylase domain Neur_chan_memb PF02932.11 ETO14563.1 - 4.8 7.0 5.8 8.8 6.1 4.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Herpes_DNAp_acc PF04929.7 ETO14563.1 - 6.7 5.5 14.9 10 4.9 10.4 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor YtkA PF13115.1 ETO14564.1 - 0.089 13.1 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 YtkA-like WW PF00397.21 ETO14565.1 - 1e-08 34.8 2.6 1.9e-08 34.0 1.8 1.5 1 0 0 1 1 1 1 WW domain Copine PF07002.11 ETO14566.1 - 5.8e-19 68.2 0.1 4.7e-09 36.1 0.0 2.3 1 1 1 2 2 2 2 Copine C2 PF00168.25 ETO14566.1 - 6.3e-19 67.6 0.8 5.5e-10 38.9 0.0 3.3 2 1 0 2 2 2 2 C2 domain DENN PF02141.16 ETO14567.1 - 7.1e-51 172.5 3.1 1.8e-50 171.2 2.1 1.8 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 ETO14567.1 - 1.8e-14 53.5 4.1 1.8e-14 53.5 2.8 2.1 2 0 0 2 2 2 1 dDENN domain uDENN PF03456.13 ETO14567.1 - 1.2e-13 50.8 0.2 3.2e-13 49.4 0.2 1.8 1 0 0 1 1 1 1 uDENN domain WD40 PF00400.27 ETO14568.1 - 5.4e-140 450.9 40.8 2.2e-11 43.1 0.0 17.2 17 0 0 17 17 17 16 WD domain, G-beta repeat NACHT PF05729.7 ETO14568.1 - 8.2e-08 32.0 0.0 1.9e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO14568.1 - 2.8e-07 30.8 0.1 1.4e-06 28.6 0.1 2.3 1 0 0 1 1 1 1 AAA domain Pentapeptide PF00805.17 ETO14568.1 - 2.2e-06 26.7 2.2 4.9e-06 25.6 1.5 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) AAA_22 PF13401.1 ETO14568.1 - 1.6e-05 25.0 0.0 5.2e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO14568.1 - 1.9e-05 25.4 0.2 0.00013 22.8 0.0 2.6 2 0 0 2 2 1 1 AAA domain Pentapeptide_4 PF13599.1 ETO14568.1 - 4.4e-05 23.2 0.3 0.00011 21.8 0.2 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 ETO14568.1 - 0.00031 20.5 0.4 0.00096 18.9 0.3 1.9 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) PD40 PF07676.7 ETO14568.1 - 0.003 17.1 21.4 15 5.3 0.1 9.6 10 0 0 10 10 10 0 WD40-like Beta Propeller Repeat RNA_helicase PF00910.17 ETO14568.1 - 0.008 16.3 0.1 0.41 10.8 0.0 3.3 2 0 0 2 2 2 1 RNA helicase Resistin PF06954.6 ETO14568.1 - 0.064 13.5 0.1 2e+02 2.3 0.0 5.1 5 1 1 6 6 6 0 Resistin eIF_4EBP PF05456.6 ETO14569.1 - 0.068 12.8 0.4 0.14 11.9 0.3 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) PAXIP1_C PF15364.1 ETO14569.1 - 0.074 12.9 4.8 0.12 12.3 3.3 1.3 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Bromodomain PF00439.20 ETO14570.1 - 5.7e-21 74.2 0.1 4.7e-20 71.2 0.0 2.4 2 0 0 2 2 2 1 Bromodomain Secretin_N_2 PF07655.8 ETO14570.1 - 1.2 9.5 24.5 4.2 7.8 17.0 2.0 1 0 0 1 1 1 0 Secretin N-terminal domain Pex14_N PF04695.8 ETO14570.1 - 3.2 7.8 10.0 0.83 9.7 4.1 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Menin PF05053.8 ETO14570.1 - 5.9 4.9 13.9 11 4.0 9.6 1.3 1 0 0 1 1 1 0 Menin DUF2490 PF10677.4 ETO14571.1 - 0.0027 16.9 0.1 0.0036 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2490) NT-C2 PF10358.4 ETO14571.1 - 0.012 15.0 8.8 0.11 11.9 6.1 2.2 1 1 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins PdxJ PF03740.8 ETO14571.1 - 0.051 12.7 1.1 0.09 11.9 0.6 1.5 1 1 0 1 1 1 0 Pyridoxal phosphate biosynthesis protein PdxJ PBP5_C PF07943.8 ETO14572.1 - 0.044 13.7 0.3 0.074 13.0 0.2 1.3 1 0 0 1 1 1 0 Penicillin-binding protein 5, C-terminal domain Kelch_5 PF13854.1 ETO14573.1 - 2.5e-06 27.3 0.6 0.036 14.0 0.1 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO14573.1 - 2.5e-06 27.4 4.4 1 9.6 0.2 4.6 3 1 1 4 4 4 3 Kelch motif Kelch_4 PF13418.1 ETO14573.1 - 3.2e-05 23.6 0.1 0.00083 19.0 0.0 3.2 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO14573.1 - 0.00029 20.4 5.8 0.05 13.4 0.1 4.2 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.20 ETO14573.1 - 0.18 11.3 6.1 0.81 9.2 0.2 4.0 4 0 0 4 4 4 0 Kelch motif Nucleoplasmin PF03066.10 ETO14574.1 - 0.37 10.3 21.1 1.8 8.0 4.8 2.6 2 0 0 2 2 2 0 Nucleoplasmin GAS PF13851.1 ETO14577.1 - 0.013 14.6 29.9 0.026 13.7 20.7 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Myosin_tail_1 PF01576.14 ETO14577.1 - 0.032 11.9 33.9 0.059 11.0 23.5 1.4 1 1 0 1 1 1 0 Myosin tail MCPsignal PF00015.16 ETO14577.1 - 0.16 11.5 5.4 0.24 10.9 3.8 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.7 ETO14577.1 - 0.19 11.5 15.3 0.089 12.5 4.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 ETO14577.1 - 0.45 9.6 3.1 0.66 9.0 2.1 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein HlyD PF00529.15 ETO14577.1 - 0.53 9.5 15.3 0.71 9.1 10.6 1.3 1 0 0 1 1 1 0 HlyD family secretion protein DUF3450 PF11932.3 ETO14577.1 - 1.3 8.2 28.5 3.4 6.8 7.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FUSC PF04632.7 ETO14577.1 - 1.6 7.0 3.8 2.2 6.6 2.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family FliD_N PF02465.13 ETO14577.1 - 2.6 8.4 15.6 3.1 8.2 3.3 2.5 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF3584 PF12128.3 ETO14577.1 - 3.5 4.8 34.7 4.3 4.5 24.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) V_ATPase_I PF01496.14 ETO14577.1 - 4.1 5.1 16.6 5.5 4.7 11.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PilJ PF13675.1 ETO14577.1 - 4.1 7.7 13.8 14 6.0 2.7 2.5 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Sec20 PF03908.8 ETO14577.1 - 4.4 7.0 11.7 12 5.7 3.8 3.0 1 1 1 2 2 2 0 Sec20 TMF_TATA_bd PF12325.3 ETO14577.1 - 5.8 6.6 26.4 1.1 9.0 5.5 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding NPV_P10 PF05531.7 ETO14577.1 - 6.1 7.1 12.4 5.5 7.3 0.6 2.5 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Peptidase_C14 PF00656.17 ETO14580.1 - 1.8e-08 34.3 0.4 6.2e-06 26.0 0.3 2.5 1 1 0 1 1 1 1 Caspase domain FAD_binding_1 PF00667.15 ETO14580.1 - 0.017 14.5 0.1 0.032 13.6 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain DUF3038 PF11237.3 ETO14580.1 - 0.068 12.9 0.8 0.31 10.8 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3038) GvpO PF05800.6 ETO14580.1 - 0.11 12.4 0.1 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpO TPR_12 PF13424.1 ETO14581.1 - 1.9e-109 357.7 30.3 3.9e-25 87.5 0.3 5.0 1 1 4 6 6 6 6 Tetratricopeptide repeat TPR_11 PF13414.1 ETO14581.1 - 1.2e-51 172.1 49.7 9.2e-13 47.6 3.4 4.9 2 1 4 6 6 6 6 TPR repeat TPR_10 PF13374.1 ETO14581.1 - 4.7e-45 150.2 0.0 5.3e-07 29.3 0.0 7.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETO14581.1 - 6.2e-43 142.7 48.6 1.1e-07 31.1 0.5 8.3 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_7 PF13176.1 ETO14581.1 - 2.9e-36 120.3 12.0 4e-07 29.3 0.0 8.4 8 1 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.12 ETO14581.1 - 2.5e-34 114.3 35.5 3e-06 26.7 0.3 8.3 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.1 ETO14581.1 - 7.6e-29 97.3 51.7 4.5e-05 22.9 0.2 7.9 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_17 PF13431.1 ETO14581.1 - 8.9e-20 69.1 20.5 0.0046 17.0 0.7 8.4 6 2 1 8 8 7 7 Tetratricopeptide repeat TPR_16 PF13432.1 ETO14581.1 - 3.8e-14 52.9 0.1 0.00031 21.3 0.0 6.1 3 1 4 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO14581.1 - 1.9e-11 43.5 0.0 0.032 14.8 0.0 7.2 5 2 3 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO14581.1 - 2.8e-10 39.9 9.9 0.53 10.8 0.1 7.5 8 0 0 8 8 7 2 Tetratricopeptide repeat DUF2225 PF09986.4 ETO14581.1 - 2.9e-09 36.7 19.8 0.013 14.9 2.8 4.7 1 1 3 5 5 5 4 Uncharacterized protein conserved in bacteria (DUF2225) Apc3 PF12895.2 ETO14581.1 - 4.8e-09 36.2 28.7 0.0026 17.8 1.1 6.3 1 1 5 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO14581.1 - 2.9e-06 27.5 6.1 1.6 9.1 0.0 5.2 1 1 7 8 8 8 1 Tetratricopeptide repeat MIT PF04212.13 ETO14581.1 - 5.9e-05 22.8 26.1 1.2 9.1 0.5 7.3 7 1 1 8 8 8 1 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 ETO14581.1 - 0.00013 21.6 27.3 0.032 14.0 1.1 6.7 6 0 0 6 6 6 1 Tetratricopeptide repeat DUF627 PF04781.7 ETO14581.1 - 0.0018 17.8 18.3 0.051 13.1 0.3 6.1 1 1 4 6 6 6 1 Protein of unknown function (DUF627) Ten1_2 PF15490.1 ETO14581.1 - 0.0028 17.2 0.0 14 5.3 0.0 4.4 2 2 0 4 4 4 0 Telomere-capping, CST complex subunit TPR_21 PF09976.4 ETO14581.1 - 0.0079 16.1 0.2 0.038 13.9 0.1 2.2 1 1 0 1 1 1 1 Tetratricopeptide repeat Ten1 PF12658.2 ETO14581.1 - 0.022 14.5 0.0 0.46 10.2 0.0 2.7 3 0 0 3 3 3 0 Telomere capping, CST complex subunit TPR_9 PF13371.1 ETO14581.1 - 0.022 14.5 0.0 1 9.2 0.0 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat P22_AR_C PF10548.4 ETO14581.1 - 0.023 14.5 6.3 19 5.1 0.0 4.9 5 0 0 5 5 5 0 P22AR C-terminal domain SHNi-TPR PF10516.4 ETO14581.1 - 0.043 13.0 5.3 56 3.0 0.0 5.7 7 0 0 7 7 5 0 SHNi-TPR ACDC PF14733.1 ETO14581.1 - 0.077 13.1 5.8 1.7 8.8 0.2 3.5 4 0 0 4 4 2 0 AP2-coincident C-terminal PPR PF01535.15 ETO14581.1 - 0.12 12.4 14.9 1.8 8.6 0.1 6.6 8 0 0 8 8 7 0 PPR repeat DUF2670 PF10875.3 ETO14581.1 - 0.39 10.7 3.1 7.6 6.5 0.2 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2670) Fis1_TPR_C PF14853.1 ETO14581.1 - 0.62 9.9 23.8 4.7 7.1 0.1 6.5 7 0 0 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat PPR_2 PF13041.1 ETO14581.1 - 4.1 7.4 10.1 1.7 8.7 0.1 4.1 6 0 0 6 6 4 0 PPR repeat family Mob_Pre PF01076.14 ETO14581.1 - 7.3 6.1 14.7 30 4.1 0.8 3.7 1 1 2 3 3 3 0 Plasmid recombination enzyme Ank_2 PF12796.2 ETO14582.1 - 8.7e-20 70.8 4.2 6.2e-10 39.2 0.1 2.6 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETO14582.1 - 1.1e-18 65.9 1.9 0.00017 21.2 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 ETO14582.1 - 6.4e-18 63.0 3.6 0.0026 17.8 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 ETO14582.1 - 7.3e-17 61.3 2.3 7e-06 26.4 0.1 3.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO14582.1 - 2.1e-10 40.4 3.7 2.6e-05 24.2 0.2 5.0 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Reprolysin_3 PF13582.1 ETO14583.1 - 0.066 13.7 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF3825 PF12873.2 ETO14584.1 - 2.8e-19 69.2 0.7 6.8e-19 67.9 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3825) Dynamin_N PF00350.18 ETO14584.1 - 0.084 12.6 4.8 0.25 11.1 3.3 2.0 1 1 0 1 1 1 0 Dynamin family DUF3987 PF13148.1 ETO14584.1 - 0.14 10.6 4.5 0.26 9.7 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) NTP_transferase PF00483.18 ETO14585.1 - 3.4e-11 42.9 0.0 6.7e-11 41.9 0.0 1.4 1 1 0 1 1 1 1 Nucleotidyl transferase GHMP_kinases_N PF00288.21 ETO14585.1 - 6.2e-09 35.7 0.0 1.4e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GalKase_gal_bdg PF10509.4 ETO14585.1 - 0.053 12.8 0.2 0.15 11.3 0.0 1.8 2 0 0 2 2 2 0 Galactokinase galactose-binding signature Mic1 PF07035.7 ETO14586.1 - 1.5e-12 47.2 0.6 2.1e-05 23.9 0.2 2.4 2 0 0 2 2 2 2 Colon cancer-associated protein Mic1-like CobT PF06213.7 ETO14586.1 - 0.003 16.7 4.6 0.0048 16.0 3.2 1.2 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT CDC45 PF02724.9 ETO14586.1 - 0.031 12.3 8.2 0.049 11.6 5.7 1.2 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.12 ETO14586.1 - 0.063 13.0 3.4 0.066 13.0 1.5 1.7 2 0 0 2 2 2 0 DDHD domain Cytomega_UL84 PF06284.6 ETO14586.1 - 0.18 10.1 4.8 0.28 9.5 3.3 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Vfa1 PF08432.5 ETO14586.1 - 0.41 10.6 13.2 0.82 9.6 9.1 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TRAP_alpha PF03896.11 ETO14586.1 - 0.45 9.4 7.4 0.84 8.5 5.1 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2052 PF09747.4 ETO14586.1 - 0.78 9.6 19.9 0.047 13.6 9.0 2.2 2 1 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF2457 PF10446.4 ETO14586.1 - 1.1 7.9 18.2 2 7.0 12.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FAM176 PF14851.1 ETO14586.1 - 1.8 8.2 9.9 4.7 6.8 6.9 1.6 1 0 0 1 1 1 0 FAM176 family Myc_N PF01056.13 ETO14586.1 - 3.2 6.8 10.7 8 5.5 7.0 1.9 2 0 0 2 2 2 0 Myc amino-terminal region Rtf2 PF04641.7 ETO14586.1 - 3.4 6.7 13.3 1.3 8.1 6.3 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger Sec62 PF03839.11 ETO14586.1 - 8.2 5.7 8.8 16 4.8 6.1 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 PBP1_TM PF14812.1 ETO14586.1 - 8.8 6.7 15.2 20 5.5 10.5 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal APC_CDC26 PF10471.4 ETO14587.1 - 0.2 12.3 4.2 0.42 11.3 2.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Zip PF02535.17 ETO14587.1 - 5.1 5.9 4.9 6.2 5.7 3.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF948 PF06103.6 ETO14588.1 - 0.0095 15.7 5.1 0.0095 15.7 3.5 7.1 4 3 2 6 6 6 4 Bacterial protein of unknown function (DUF948) CX PF01705.14 ETO14588.1 - 5.1 7.1 7.2 1.5 8.8 0.0 3.6 4 0 0 4 4 4 0 CX module Reo_sigmaC PF04582.7 ETO14588.1 - 5.5 6.0 42.5 0.13 11.3 4.0 5.5 3 2 3 6 6 6 0 Reovirus sigma C capsid protein Tetraspannin PF00335.15 ETO14589.1 - 7.5e-16 58.0 16.3 1.1e-15 57.5 11.3 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF3611 PF12263.3 ETO14589.1 - 0.32 10.3 7.5 0.049 13.0 1.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3611) PDGLE PF13190.1 ETO14589.1 - 8.5 6.1 7.2 0.68 9.6 0.9 2.3 2 1 0 2 2 2 0 PDGLE domain WD40 PF00400.27 ETO14590.1 - 6.1e-167 536.3 45.7 5e-13 48.3 0.4 16.3 16 0 0 16 16 16 16 WD domain, G-beta repeat Nup160 PF11715.3 ETO14590.1 - 3.4e-18 65.0 21.7 0.71 7.9 0.0 12.9 2 2 10 13 13 13 10 Nucleoporin Nup120/160 Pentapeptide PF00805.17 ETO14590.1 - 3e-06 26.3 1.1 9.2e-06 24.7 0.6 1.8 1 1 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO14590.1 - 5.6e-06 26.0 0.2 1.5e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Cytochrom_D1 PF02239.11 ETO14590.1 - 1.5e-05 23.5 12.6 0.76 8.0 0.1 6.3 5 1 1 6 6 6 3 Cytochrome D1 heme domain Pentapeptide_3 PF13576.1 ETO14590.1 - 0.00018 21.3 0.1 0.00054 19.7 0.1 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) CelD_N PF02927.9 ETO14590.1 - 0.02 15.1 0.0 12 6.2 0.0 4.4 4 1 0 4 4 4 0 N-terminal ig-like domain of cellulase DUF1258 PF06869.7 ETO14590.1 - 0.028 13.5 6.4 0.83 8.6 0.0 5.4 6 2 1 8 8 8 0 Protein of unknown function (DUF1258) PD40 PF07676.7 ETO14590.1 - 0.034 13.8 21.1 38 4.0 0.1 9.7 11 0 0 11 11 11 0 WD40-like Beta Propeller Repeat Mid2 PF04478.7 ETO14590.1 - 0.034 13.5 17.1 10 5.5 0.1 8.0 6 4 4 10 10 10 0 Mid2 like cell wall stress sensor Surfac_D-trimer PF09006.6 ETO14590.1 - 0.074 12.7 0.2 7.9 6.2 0.1 4.1 4 0 0 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation UPF0147 PF03685.8 ETO14590.1 - 0.087 12.7 1.1 0.32 10.8 0.8 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) Peptidase_C69 PF03577.10 ETO14590.1 - 0.17 10.7 10.7 3.6 6.3 0.0 6.7 8 1 1 9 9 9 0 Peptidase family C69 NYD-SP28_assoc PF14775.1 ETO14590.1 - 2.2 8.0 22.1 8.7 6.1 0.0 10.2 15 0 0 15 15 15 0 Sperm tail C-terminal domain Peptidase_S10 PF00450.17 ETO14591.1 - 2.7e-53 181.6 0.4 7.8e-53 180.1 0.3 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase WD40 PF00400.27 ETO14593.1 - 1.4e-65 215.0 23.9 5.4e-12 45.1 1.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO14593.1 - 8.1e-14 50.6 11.3 6.2e-05 21.3 0.2 5.3 2 2 3 5 5 5 5 Nucleoporin Nup120/160 Apocytochr_F_C PF01333.14 ETO14593.1 - 6.5 6.6 5.7 3.3 7.5 2.0 1.9 2 0 0 2 2 2 0 Apocytochrome F, C-terminal AAA_24 PF13479.1 ETO14594.1 - 7.8e-05 22.3 0.2 0.00027 20.5 0.1 2.0 1 0 0 1 1 1 1 AAA domain Afi1 PF07792.7 ETO14595.1 - 0.76 9.7 6.9 4.5 7.2 0.8 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SBDS PF01172.13 ETO14596.1 - 4.2e-16 58.5 0.3 5.1e-16 58.2 0.2 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF4369 PF14289.1 ETO14596.1 - 0.042 13.8 0.0 8.5 6.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4369) cobW PF02492.14 ETO14597.1 - 0.00016 21.1 0.0 0.00027 20.4 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Phage_CRI PF05144.9 ETO14598.1 - 0.076 12.1 0.6 0.12 11.4 0.3 1.5 1 1 0 1 1 1 0 Phage replication protein CRI Fn3-like PF14310.1 ETO14599.1 - 8.3e-07 28.8 0.2 1.8e-06 27.7 0.2 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF11 PF01345.13 ETO14599.1 - 0.0024 17.8 0.6 0.0066 16.4 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF11 Glyco_hydro_3_C PF01915.17 ETO14599.1 - 0.074 12.5 0.2 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Ank_2 PF12796.2 ETO14600.1 - 3.6e-08 33.6 0.4 1.3e-07 31.8 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO14600.1 - 2.2e-07 30.3 0.0 3.3e-06 26.6 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 ETO14600.1 - 1.5e-06 27.8 0.0 0.0074 16.4 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 ETO14600.1 - 3e-06 27.2 8.3 1.6e-05 24.9 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO14600.1 - 0.0049 17.3 0.1 0.024 15.1 0.1 2.3 1 1 0 1 1 1 1 Ankyrin repeats (many copies) WD40 PF00400.27 ETO14601.1 - 6.2e-13 48.0 4.0 8.2e-09 35.0 0.7 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Tim54 PF11711.3 ETO14602.1 - 0.001 17.7 1.1 0.0011 17.6 0.8 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.9 ETO14602.1 - 0.0057 14.7 3.5 0.0059 14.7 2.4 1.0 1 0 0 1 1 1 1 CDC45-like protein Pex14_N PF04695.8 ETO14602.1 - 0.011 15.8 0.1 0.012 15.6 0.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Apis_Csd PF11671.3 ETO14602.1 - 0.037 13.8 2.1 0.038 13.7 1.5 1.1 1 0 0 1 1 1 0 Complementary sex determiner protein OHCU_decarbox PF09349.5 ETO14602.1 - 0.038 14.2 0.6 0.047 13.9 0.4 1.3 1 1 0 1 1 1 0 OHCU decarboxylase F-protein PF00469.15 ETO14602.1 - 0.047 13.0 1.9 0.047 13.0 1.3 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef CPSF100_C PF13299.1 ETO14602.1 - 0.1 12.7 5.0 0.13 12.4 3.4 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Peroxin-13_N PF04088.8 ETO14602.1 - 0.11 12.5 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region FYDLN_acid PF09538.5 ETO14602.1 - 0.13 12.8 12.0 0.17 12.4 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) SID-1_RNA_chan PF13965.1 ETO14602.1 - 0.21 9.7 1.3 0.23 9.5 0.9 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 YqfQ PF14181.1 ETO14602.1 - 0.39 10.7 6.0 0.45 10.5 4.2 1.1 1 0 0 1 1 1 0 YqfQ-like protein Sec62 PF03839.11 ETO14602.1 - 0.43 9.9 3.8 0.48 9.7 2.6 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Ycf1 PF05758.7 ETO14602.1 - 0.48 8.0 5.6 0.52 7.9 3.9 1.0 1 0 0 1 1 1 0 Ycf1 Nop14 PF04147.7 ETO14602.1 - 0.62 7.9 11.3 0.7 7.7 7.8 1.0 1 0 0 1 1 1 0 Nop14-like family NPR3 PF03666.8 ETO14602.1 - 0.66 8.4 5.7 0.79 8.1 4.0 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 AIF_C PF14721.1 ETO14602.1 - 0.92 9.7 5.4 1.1 9.5 3.7 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Vma12 PF11712.3 ETO14602.1 - 1.1 8.9 3.7 1.4 8.6 2.6 1.1 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Pox_Ag35 PF03286.9 ETO14602.1 - 2.4 7.6 14.3 3.1 7.2 9.9 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TFIIF_alpha PF05793.7 ETO14602.1 - 4.5 5.5 19.1 5.4 5.2 13.2 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Menin PF05053.8 ETO14602.1 - 5.1 5.1 8.5 6 4.8 5.9 1.0 1 0 0 1 1 1 0 Menin CENP-T PF15511.1 ETO14602.1 - 5.6 6.0 9.9 7 5.7 6.9 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF2457 PF10446.4 ETO14602.1 - 6.5 5.3 17.1 7.6 5.1 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF3043 PF11241.3 ETO14602.1 - 8.4 5.9 6.3 10 5.6 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Daxx PF03344.10 ETO14602.1 - 8.8 4.6 16.2 11 4.4 11.3 1.0 1 0 0 1 1 1 0 Daxx Family TRAPPC9-Trs120 PF08626.6 ETO14604.1 - 0.0032 14.8 0.1 0.0038 14.6 0.1 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Transglut_C PF00927.17 ETO14604.1 - 0.41 10.7 2.4 5.6 7.0 1.7 2.3 1 1 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain DUF506 PF04720.7 ETO14606.1 - 5.9 6.4 15.8 0.3 10.6 0.7 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF506) ELO PF01151.13 ETO14607.1 - 1.4e-55 188.3 30.0 1.6e-55 188.1 20.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Equine_IAV_S2 PF06502.6 ETO14607.1 - 0.042 13.7 0.1 0.098 12.5 0.1 1.7 1 0 0 1 1 1 0 Equine infectious anaemia virus S2 protein PCMT PF01135.14 ETO14608.1 - 1.2e-20 74.0 0.0 2.9e-20 72.7 0.0 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 ETO14608.1 - 8.7e-09 35.9 0.0 1.6e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO14608.1 - 1.7e-08 34.1 0.0 3.4e-08 33.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETO14608.1 - 6.4e-05 23.2 0.0 0.00013 22.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 ETO14608.1 - 0.00016 21.3 0.0 0.00039 20.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 ETO14608.1 - 0.00022 20.8 0.0 0.00038 20.0 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 ETO14608.1 - 0.00092 19.2 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETO14608.1 - 0.0022 17.7 0.0 0.004 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO14608.1 - 0.018 15.4 0.0 0.039 14.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 ETO14608.1 - 0.096 12.0 0.0 0.39 10.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain FlaC_arch PF05377.6 ETO14608.1 - 0.1 12.5 1.4 0.18 11.7 1.0 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Methyltransf_11 PF08241.7 ETO14608.1 - 0.1 13.1 0.0 0.29 11.6 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain TMF_DNA_bd PF12329.3 ETO14608.1 - 1.3 8.8 7.0 0.15 11.9 1.7 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding zf-TRAF PF02176.13 ETO14609.1 - 9e-06 25.9 3.1 9e-06 25.9 2.1 2.8 3 1 0 3 3 3 1 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 ETO14609.1 - 0.00043 20.2 3.6 0.00043 20.2 2.5 2.6 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RAP1 PF07218.6 ETO14609.1 - 0.0067 14.5 2.0 0.0081 14.3 1.4 1.1 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) Daxx PF03344.10 ETO14610.1 - 0.23 9.9 24.6 0.27 9.6 17.0 1.0 1 0 0 1 1 1 0 Daxx Family Peptidase_C58 PF03543.9 ETO14610.1 - 0.62 9.5 10.4 0.76 9.2 7.2 1.1 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen DUF4628 PF15429.1 ETO14610.1 - 0.73 9.2 11.5 0.84 9.0 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) CENP-T PF15511.1 ETO14610.1 - 0.78 8.9 15.4 0.8 8.8 10.7 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Strabismus PF06638.6 ETO14610.1 - 1.3 7.2 4.6 1.3 7.2 3.2 1.0 1 0 0 1 1 1 0 Strabismus protein DDRGK PF09756.4 ETO14610.1 - 1.6 8.0 22.4 2 7.7 15.5 1.1 1 0 0 1 1 1 0 DDRGK domain Mem_trans PF03547.13 ETO14610.1 - 2.4 6.3 9.3 2.9 6.0 6.4 1.2 1 0 0 1 1 1 0 Membrane transport protein Neur_chan_memb PF02932.11 ETO14610.1 - 3.6 7.4 10.9 4.2 7.1 7.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4045 PF13254.1 ETO14610.1 - 3.8 6.6 14.0 4.3 6.5 9.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) MRP-S27 PF10037.4 ETO14610.1 - 4.3 6.1 14.8 4.7 6.0 10.3 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Mnd1 PF03962.10 ETO14610.1 - 4.9 6.7 19.2 6.1 6.4 13.3 1.1 1 0 0 1 1 1 0 Mnd1 family Zip PF02535.17 ETO14610.1 - 5 6.0 12.5 5.3 5.9 8.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter VSG_B PF13206.1 ETO14610.1 - 6.1 5.8 11.7 6.9 5.6 8.1 1.0 1 0 0 1 1 1 0 Trypanosomal VSG domain Rho_GDI PF02115.12 ETO14610.1 - 6.5 6.1 16.8 10 5.4 11.6 1.4 1 1 0 1 1 1 0 RHO protein GDP dissociation inhibitor HSP70 PF00012.15 ETO14610.1 - 6.8 4.4 20.3 7.8 4.2 14.1 1.1 1 0 0 1 1 1 0 Hsp70 protein Ycf1 PF05758.7 ETO14610.1 - 7.3 4.1 19.0 8.1 4.0 13.2 1.1 1 0 0 1 1 1 0 Ycf1 Caldesmon PF02029.10 ETO14610.1 - 7.6 4.8 26.1 8.9 4.6 18.1 1.0 1 0 0 1 1 1 0 Caldesmon SDA1 PF05285.7 ETO14610.1 - 8.6 5.5 26.8 9.3 5.4 18.6 1.0 1 0 0 1 1 1 0 SDA1 SAPS PF04499.10 ETO14610.1 - 9 4.7 16.4 9.8 4.6 11.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Daxx PF03344.10 ETO14611.1 - 0.81 8.0 33.0 1 7.7 22.9 1.0 1 0 0 1 1 1 0 Daxx Family SAPS PF04499.10 ETO14611.1 - 3 6.3 19.6 3.9 6.0 13.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TFIIA PF03153.8 ETO14611.1 - 3.1 7.6 34.5 3.8 7.2 23.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ycf1 PF05758.7 ETO14611.1 - 3.6 5.1 22.7 4.6 4.8 15.7 1.1 1 0 0 1 1 1 0 Ycf1 DUF1675 PF07897.6 ETO14611.1 - 3.8 7.2 19.2 4.7 7.0 13.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Hid1 PF12722.2 ETO14611.1 - 4 4.9 25.6 4.8 4.7 17.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4045 PF13254.1 ETO14611.1 - 5.1 6.2 20.1 6.5 5.9 13.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF4175 PF13779.1 ETO14611.1 - 7.3 4.1 44.2 11 3.5 30.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CAGE1 PF15066.1 ETO14612.1 - 0.04 12.3 0.7 0.048 12.1 0.5 1.1 1 0 0 1 1 1 0 Cancer-associated gene protein 1 family TrbH PF07283.6 ETO14612.1 - 0.08 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Conjugal transfer protein TrbH Aconitase PF00330.15 ETO14614.1 - 3e-161 537.0 0.0 5.8e-161 536.0 0.0 1.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 ETO14614.1 - 2e-42 144.3 0.0 5e-42 143.1 0.0 1.7 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.8 ETO14614.1 - 0.00098 17.7 0.0 0.002 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF521) DUF955 PF06114.8 ETO14614.1 - 0.21 11.3 0.0 0.4 10.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF955) Kelch_6 PF13964.1 ETO14615.1 - 1.6e-13 50.2 1.6 1.7e-06 27.9 0.1 4.4 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO14615.1 - 1.6e-10 40.3 4.5 8.3e-07 28.4 0.1 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO14615.1 - 8e-08 31.9 2.5 7.5e-05 22.4 0.0 3.0 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO14615.1 - 6.1e-07 29.2 4.6 0.00022 21.0 0.7 4.3 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.1 ETO14615.1 - 3.8e-05 23.7 0.0 0.0013 18.8 0.0 3.0 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO14615.1 - 0.01 15.5 4.8 0.38 10.5 0.1 4.1 5 1 0 5 5 5 0 Kelch motif DUF740 PF05340.7 ETO14615.1 - 0.024 13.0 0.3 0.038 12.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Cast PF10174.4 ETO14615.1 - 0.094 10.7 2.0 0.13 10.3 1.4 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone WD40 PF00400.27 ETO14617.1 - 2.7e-23 80.9 3.9 1.9e-08 33.8 0.1 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat Resistin PF06954.6 ETO14617.1 - 0.043 14.0 0.4 13 6.1 0.0 3.5 2 2 1 4 4 4 0 Resistin Rhodanese PF00581.15 ETO14617.1 - 0.12 12.7 0.1 21 5.4 0.0 2.6 2 1 0 2 2 2 0 Rhodanese-like domain Cytochrom_D1 PF02239.11 ETO14617.1 - 0.12 10.6 0.0 0.17 10.1 0.0 1.1 1 0 0 1 1 1 0 Cytochrome D1 heme domain HSP70 PF00012.15 ETO14618.1 - 4.7e-126 421.1 0.2 8.4e-125 416.9 0.1 2.0 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 ETO14618.1 - 0.0017 17.0 0.1 0.0047 15.5 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein DUF2645 PF10840.3 ETO14618.1 - 0.011 15.8 0.1 0.027 14.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2645) Peptidase_M16 PF00675.15 ETO14618.1 - 0.034 13.8 0.1 0.12 12.0 0.1 1.9 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) DUF4199 PF13858.1 ETO14618.1 - 0.041 13.7 2.3 4.7 7.1 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Orbi_VP6 PF01516.11 ETO14620.1 - 1.1 8.2 8.2 1.7 7.6 5.7 1.2 1 0 0 1 1 1 0 Orbivirus helicase VP6 PcfK PF14058.1 ETO14620.1 - 3.2 7.8 11.7 6.5 6.8 8.1 1.6 1 1 0 1 1 1 0 PcfK-like protein Trypan_PARP PF05887.6 ETO14620.1 - 5.1 6.8 9.8 6.8 6.5 6.8 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4407 PF14362.1 ETO14620.1 - 6.1 5.7 8.5 7.1 5.4 5.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.7 ETO14620.1 - 7.7 6.3 10.7 9.8 5.9 7.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 p450 PF00067.17 ETO14621.1 - 6.3e-12 44.7 2.8 6.8e-12 44.6 1.9 1.1 1 0 0 1 1 1 1 Cytochrome P450 HECA PF15353.1 ETO14621.1 - 0.14 11.9 2.7 0.95 9.2 1.2 2.3 2 0 0 2 2 2 0 Headcase protein family homologue Spc97_Spc98 PF04130.8 ETO14622.1 - 1.6e-09 36.6 3.2 1.6e-09 36.6 2.2 1.4 2 0 0 2 2 2 1 Spc97 / Spc98 family YMF19 PF02326.10 ETO14622.1 - 0.59 10.7 13.1 0.089 13.3 5.2 2.6 3 0 0 3 3 3 0 Plant ATP synthase F0 ATP-synt_8 PF00895.15 ETO14622.1 - 1.5 9.1 8.8 0.45 10.7 2.4 2.6 2 0 0 2 2 2 0 ATP synthase protein 8 WD40 PF00400.27 ETO14623.1 - 8.4e-44 145.9 19.8 2.2e-13 49.5 0.1 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO14623.1 - 1.8e-10 39.5 1.8 0.002 16.3 0.0 4.0 1 1 2 4 4 4 4 Nucleoporin Nup120/160 BTB PF00651.26 ETO14624.1 - 5.1e-14 52.2 0.1 1.1e-13 51.1 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain PHR PF08005.7 ETO14624.1 - 7.1e-12 45.7 1.4 7.4e-12 45.6 0.1 1.7 2 0 0 2 2 2 1 PHR domain DRIM PF07539.7 ETO14624.1 - 0.028 13.8 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 Down-regulated in metastasis zf-CCCH PF00642.19 ETO14625.1 - 1.6e-09 37.2 1.1 3.1e-09 36.3 0.8 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Secretin_N_2 PF07655.8 ETO14625.1 - 0.18 12.2 17.0 0.63 10.4 11.8 1.9 1 0 0 1 1 1 0 Secretin N-terminal domain COX6B PF02297.12 ETO14626.1 - 3.9 7.5 9.3 0.88 9.6 3.2 2.2 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIb Phage_cap_P2 PF05125.7 ETO14627.1 - 0.037 12.9 0.0 0.052 12.4 0.0 1.2 1 0 0 1 1 1 0 Phage major capsid protein, P2 family DUF4488 PF14869.1 ETO14627.1 - 0.073 12.6 0.4 1.2 8.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4488) HCaRG PF07258.9 ETO14628.1 - 2.4e-13 50.0 2.2 3e-13 49.7 1.5 1.3 1 1 0 1 1 1 1 HCaRG protein SusE PF14292.1 ETO14628.1 - 0.012 15.4 1.3 0.67 9.7 0.1 2.3 2 0 0 2 2 2 0 SusE outer membrane protein DUF2140 PF09911.4 ETO14628.1 - 0.12 11.5 0.6 0.81 8.8 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) eIF2A PF08662.6 ETO14630.1 - 0.00064 19.4 0.9 0.017 14.8 0.0 2.4 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO14630.1 - 0.011 15.4 0.1 41 3.9 0.0 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 ETO14630.1 - 0.02 14.0 0.1 1.6 7.7 0.0 2.8 3 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal TRAPP PF04051.11 ETO14630.1 - 0.032 13.7 1.5 1 8.8 0.1 2.5 1 1 1 2 2 2 0 Transport protein particle (TRAPP) component Mid2 PF04478.7 ETO14630.1 - 0.048 13.0 1.0 21 4.5 0.0 3.3 2 1 1 3 3 3 0 Mid2 like cell wall stress sensor WD40 PF00400.27 ETO14630.1 - 0.11 12.3 3.3 40 4.2 0.0 4.4 4 1 0 4 4 4 0 WD domain, G-beta repeat GLE1 PF07817.8 ETO14631.1 - 3.2e-08 32.8 0.0 4.2e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 GLE1-like protein DUF1803 PF08820.5 ETO14631.1 - 0.11 12.1 0.6 0.17 11.6 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1803) Rnk_N PF14760.1 ETO14633.1 - 1.7 8.7 7.2 6.3 6.9 0.3 2.7 2 0 0 2 2 2 0 Rnk N-terminus SET PF00856.23 ETO14634.1 - 2.9e-05 24.4 0.1 6.8e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 SET domain Shisa PF13908.1 ETO14637.1 - 0.0026 17.9 2.5 0.0039 17.4 1.8 1.3 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator MpPF26 PF07666.6 ETO14637.1 - 0.12 12.2 9.2 1.9 8.4 0.1 2.3 2 0 0 2 2 2 0 M penetrans paralogue family 26 Chordopox_A33R PF05966.7 ETO14637.1 - 0.5 9.1 4.0 0.69 8.6 2.6 1.4 1 1 0 1 1 1 0 Chordopoxvirus A33R protein DUF4446 PF14584.1 ETO14637.1 - 0.64 9.8 3.9 0.28 11.0 1.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Herpes_UL45 PF05473.7 ETO14637.1 - 1.8 7.9 5.2 1.4 8.3 0.1 2.1 2 0 0 2 2 2 0 UL45 protein NS3_envE PF02723.9 ETO14637.1 - 4.9 7.1 8.9 13 5.7 6.2 1.7 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E Na_Ca_ex PF01699.19 ETO14638.1 - 0.063 12.8 4.4 1.3 8.6 0.0 2.5 2 0 0 2 2 2 0 Sodium/calcium exchanger protein EF-hand_1 PF00036.27 ETO14639.1 - 4e-16 57.0 11.7 1.7e-05 23.7 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 ETO14639.1 - 1e-12 46.7 10.6 0.00052 19.6 0.5 3.9 2 1 1 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 ETO14639.1 - 1.8e-10 40.2 6.0 0.0026 17.3 0.0 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.1 ETO14639.1 - 5.5e-10 39.2 11.4 9.3e-05 22.4 6.1 3.2 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 ETO14639.1 - 2e-09 36.3 15.7 0.0013 17.9 0.7 4.0 3 1 1 4 4 4 3 EF hand EF-hand_4 PF12763.2 ETO14639.1 - 7.5e-06 25.6 11.6 1.3e-05 24.9 0.9 3.0 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand Phosducin PF02114.11 ETO14639.1 - 0.031 13.0 2.0 0.042 12.5 1.4 1.2 1 0 0 1 1 1 0 Phosducin Abhydro_lipase PF04083.11 ETO14640.1 - 2.7e-21 74.6 0.0 5.2e-21 73.7 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 ETO14640.1 - 2.3e-12 46.9 0.1 4.1e-12 46.1 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETO14640.1 - 0.0005 20.0 0.0 0.0021 17.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETO14640.1 - 0.00081 19.1 0.0 0.002 17.9 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Homeobox_KN PF05920.6 ETO14641.1 - 1.2e-14 53.7 0.2 2e-14 53.0 0.1 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 ETO14641.1 - 4e-09 35.9 0.8 7.5e-09 35.0 0.6 1.4 1 0 0 1 1 1 1 Homeobox domain DUF912 PF06024.7 ETO14642.1 - 5.7 7.0 9.5 0.44 10.6 2.3 2.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) F-box PF00646.28 ETO14643.1 - 0.0033 17.0 0.7 0.0074 15.9 0.0 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 ETO14643.1 - 0.019 14.6 0.0 0.06 13.0 0.0 1.8 1 0 0 1 1 1 0 F-box-like DUF3311 PF11755.3 ETO14644.1 - 0.005 16.3 0.2 0.0081 15.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3311) zf-RanBP PF00641.13 ETO14645.1 - 2.3 7.4 7.4 0.85 8.7 1.4 2.5 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others ACDC PF14733.1 ETO14646.1 - 0.039 14.0 1.5 0.94 9.6 0.0 2.9 2 0 0 2 2 2 0 AP2-coincident C-terminal Trypan_PARP PF05887.6 ETO14646.1 - 0.057 13.2 5.4 0.1 12.3 3.8 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Neisseria_TspB PF05616.8 ETO14646.1 - 2.2 6.5 11.3 4.5 5.5 7.8 1.4 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein FixO PF02433.10 ETO14648.1 - 0.02 14.2 0.1 0.024 14.0 0.0 1.3 1 1 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO DUF4242 PF14026.1 ETO14649.1 - 0.043 13.9 0.0 0.082 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4242) Syntaxin-6_N PF09177.6 ETO14650.1 - 0.026 14.9 4.8 0.026 14.9 3.3 2.7 3 1 0 3 3 3 0 Syntaxin 6, N-terminal Kelch_4 PF13418.1 ETO14651.1 - 0.0024 17.6 0.4 3.4 7.5 0.1 4.0 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO14651.1 - 0.0049 16.3 0.6 1.6 8.3 0.1 4.0 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 ETO14651.1 - 0.067 12.9 2.0 1.9 8.3 0.1 3.8 5 0 0 5 5 5 0 Kelch motif DUF3722 PF12519.3 ETO14652.1 - 0.004 16.4 0.2 0.005 16.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Glyco_hydro_46 PF01374.13 ETO14653.1 - 0.0031 17.0 0.9 0.0038 16.8 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 DUF617 PF04759.8 ETO14653.1 - 0.078 12.6 0.0 0.087 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF617 Surp PF01805.15 ETO14653.1 - 0.13 11.9 2.9 0.15 11.6 0.4 2.2 2 0 0 2 2 2 0 Surp module RLL PF10036.4 ETO14654.1 - 1.1e-38 133.0 7.6 1.8e-37 129.1 5.2 2.0 1 1 0 1 1 1 1 Putative carnitine deficiency-associated protein UvrD-helicase PF00580.16 ETO14654.1 - 0.031 13.5 4.1 0.04 13.2 2.9 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Methyltransf_31 PF13847.1 ETO14655.1 - 0.0021 17.6 0.0 0.0056 16.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Rhodanese PF00581.15 ETO14655.1 - 0.017 15.4 0.0 0.1 12.9 0.0 2.3 1 1 0 1 1 1 0 Rhodanese-like domain Methyltransf_25 PF13649.1 ETO14655.1 - 0.031 14.6 0.0 0.064 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 ETO14655.1 - 0.097 13.1 3.9 0.18 12.2 0.0 2.8 3 1 0 3 3 3 0 Methyltransferase domain Methyltransf_23 PF13489.1 ETO14655.1 - 0.099 12.3 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain XRCC4 PF06632.7 ETO14656.1 - 0.0068 15.3 3.9 0.01 14.7 2.7 1.1 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF913 PF06025.7 ETO14656.1 - 0.024 13.3 0.1 0.035 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Mem_trans PF03547.13 ETO14656.1 - 0.092 11.0 0.5 0.12 10.6 0.4 1.1 1 0 0 1 1 1 0 Membrane transport protein RP-C_C PF11800.3 ETO14656.1 - 0.15 11.7 1.1 0.21 11.2 0.7 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region zf-RING_5 PF14634.1 ETO14656.1 - 0.16 11.6 12.1 0.05 13.3 6.1 1.8 1 1 1 2 2 2 0 zinc-RING finger domain Rtf2 PF04641.7 ETO14656.1 - 0.34 10.0 13.0 0.77 8.9 9.0 1.5 1 1 0 1 1 1 0 Rtf2 RING-finger zf-RING_2 PF13639.1 ETO14656.1 - 1.2 8.9 8.6 1.6 8.6 5.4 1.6 1 1 0 1 1 1 0 Ring finger domain DUF3408 PF11888.3 ETO14656.1 - 2.7 7.9 8.2 4 7.3 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) zf-C3HC4_4 PF15227.1 ETO14656.1 - 3.6 7.5 12.2 0.23 11.3 2.7 2.6 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING IBR PF01485.16 ETO14656.1 - 7.4 6.5 10.9 30 4.5 7.6 1.9 1 1 0 1 1 1 0 IBR domain Ribosomal_S16 PF00886.14 ETO14657.1 - 5.9e-05 22.7 0.0 0.00012 21.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S16 Myotub-related PF06602.9 ETO14659.1 - 7.6e-103 343.9 3.2 1.5e-102 343.0 2.2 1.5 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain C2 PF00168.25 ETO14659.1 - 5e-12 45.4 0.0 1.4e-11 44.0 0.0 1.9 1 0 0 1 1 1 1 C2 domain FYVE PF01363.16 ETO14659.1 - 0.0014 18.4 2.0 0.0037 17.1 1.4 1.7 1 0 0 1 1 1 1 FYVE zinc finger COP-gamma_platf PF08752.5 ETO14660.1 - 7.3e-30 103.7 2.5 1.4e-29 102.8 1.8 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_b_Cpla PF14806.1 ETO14660.1 - 0.0028 17.3 0.0 0.013 15.1 0.0 2.1 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform DUF2815 PF10991.3 ETO14660.1 - 0.045 13.2 0.5 0.3 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2815) Sugarporin_N PF11471.3 ETO14660.1 - 0.29 10.8 4.5 0.57 9.8 3.1 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension zf-DNA_Pol PF08996.5 ETO14660.1 - 0.34 10.2 2.6 0.68 9.2 0.1 2.2 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger Adaptin_N PF01602.15 ETO14661.1 - 2.9e-41 141.3 0.1 3.8e-41 141.0 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 ETO14661.1 - 0.0022 18.2 0.0 2.1 8.6 0.0 3.1 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.17 ETO14661.1 - 0.032 14.3 1.6 11 6.4 0.0 4.1 4 1 0 4 4 4 0 HEAT repeat Cnd1 PF12717.2 ETO14661.1 - 0.08 12.7 0.2 0.83 9.4 0.1 2.2 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 ETO14662.1 - 3.4e-34 118.0 0.1 4.1e-34 117.7 0.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region DUF4464 PF14713.1 ETO14664.1 - 0.046 13.1 0.9 2.4 7.5 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4464) DUF1241 PF06840.6 ETO14664.1 - 0.071 12.3 0.1 0.22 10.7 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1241) APC8 PF04049.8 ETO14664.1 - 0.075 12.7 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Anaphase promoting complex subunit 8 / Cdc23 NPV_P10 PF05531.7 ETO14664.1 - 0.37 11.0 3.6 2 8.7 0.0 2.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF106 PF01956.11 ETO14665.1 - 0.0055 16.2 3.5 0.042 13.3 0.7 2.2 2 0 0 2 2 2 2 Integral membrane protein DUF106 WD40 PF00400.27 ETO14666.1 - 9.6e-68 221.8 11.6 5.5e-13 48.2 0.1 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO14666.1 - 2.2e-06 26.1 4.9 0.051 11.7 0.1 3.6 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO14666.1 - 5e-05 21.7 1.3 0.13 10.5 0.0 2.9 1 1 4 5 5 5 4 Cytochrome D1 heme domain SGL PF08450.7 ETO14666.1 - 0.00014 21.3 0.3 0.0083 15.5 0.0 2.2 1 1 1 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Resistin PF06954.6 ETO14666.1 - 0.0086 16.3 0.0 3.6 7.9 0.0 3.5 2 2 2 4 4 4 1 Resistin PD40 PF07676.7 ETO14666.1 - 0.01 15.4 7.8 6.9 6.4 0.0 4.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 ETO14666.1 - 0.023 13.8 0.6 2.5 7.1 0.0 3.2 1 1 4 5 5 5 0 Protein of unknown function (DUF1258) WD40 PF00400.27 ETO14667.1 - 8.8e-60 196.6 12.4 4.7e-13 48.4 0.0 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 ETO14667.1 - 1.3e-08 34.8 0.3 3.5e-05 23.6 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO14667.1 - 4.4e-05 21.9 1.3 0.13 10.4 0.1 2.9 1 1 2 3 3 3 3 Cytochrome D1 heme domain Nup160 PF11715.3 ETO14667.1 - 0.00014 20.1 4.6 0.025 12.7 0.2 3.4 1 1 4 5 5 5 3 Nucleoporin Nup120/160 DPPIV_N PF00930.16 ETO14667.1 - 0.0002 20.0 0.1 0.00076 18.1 0.0 1.9 1 1 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nucleoporin_N PF08801.6 ETO14667.1 - 0.00041 19.2 5.3 0.3 9.8 0.7 3.4 1 1 3 4 4 4 2 Nup133 N terminal like Hira PF07569.6 ETO14667.1 - 0.013 14.6 0.4 1.2 8.3 0.1 2.9 2 2 1 3 3 3 0 TUP1-like enhancer of split F420_ligase PF01996.11 ETO14667.1 - 0.014 14.4 0.0 0.05 12.6 0.0 1.9 1 1 0 1 1 1 0 F420-0:Gamma-glutamyl ligase SGL PF08450.7 ETO14667.1 - 0.04 13.2 0.2 0.21 10.9 0.1 2.0 1 1 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region Resistin PF06954.6 ETO14667.1 - 0.14 12.4 1.0 10 6.4 0.0 3.4 1 1 2 3 3 3 0 Resistin Proteasome_A_N PF10584.4 ETO14667.1 - 0.18 11.1 1.3 6.3 6.2 0.0 3.1 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature TFIIIC_delta PF12657.2 ETO14667.1 - 1.2 8.8 7.3 5.8 6.5 0.1 3.6 2 2 1 3 3 3 0 Transcription factor IIIC subunit delta N-term Kelch_6 PF13964.1 ETO14668.1 - 0.0033 17.5 5.4 0.78 10.0 0.2 3.2 3 1 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 ETO14668.1 - 0.011 15.2 2.7 0.63 9.6 0.2 2.5 2 0 0 2 2 2 0 Kelch motif Kelch_2 PF07646.10 ETO14668.1 - 1.1 9.1 5.3 3.4 7.5 0.1 3.1 3 1 0 3 3 3 0 Kelch motif Lung_7-TM_R PF06814.8 ETO14669.1 - 2.3e-19 69.4 26.9 5.3e-19 68.2 18.6 1.5 1 1 0 1 1 1 1 Lung seven transmembrane receptor Vpu PF00558.14 ETO14669.1 - 0.5 9.9 0.1 0.5 9.9 0.0 2.2 2 0 0 2 2 2 0 Vpu protein DUF3290 PF11694.3 ETO14669.1 - 0.95 9.1 7.0 0.059 13.1 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) PSRP-3_Ycf65 PF04839.8 ETO14670.1 - 0.16 12.0 3.9 0.24 11.5 1.0 2.1 2 0 0 2 2 2 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) WD40 PF00400.27 ETO14671.1 - 2.3e-55 182.6 24.2 3e-11 42.7 0.4 7.2 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO14671.1 - 3.2e-07 28.8 8.2 0.13 10.3 0.1 5.7 1 1 4 5 5 5 5 Nucleoporin Nup120/160 HAD PF12710.2 ETO14671.1 - 0.024 14.7 4.1 0.27 11.3 0.1 3.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase zf-RING_2 PF13639.1 ETO14672.1 - 0.00015 21.5 1.3 0.00039 20.1 0.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO14672.1 - 0.00018 21.4 1.5 0.0011 18.9 1.0 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1644 PF07800.7 ETO14672.1 - 0.0032 17.3 3.7 0.0056 16.5 2.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1644) zf-C3HC4 PF00097.20 ETO14672.1 - 0.077 12.6 3.3 1.6 8.4 2.3 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETO14672.1 - 0.25 11.4 4.2 0.67 10.1 2.9 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 ETO14672.1 - 0.85 9.3 4.8 6.7 6.4 3.3 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 ETO14672.1 - 4.7 7.3 8.1 16 5.5 4.9 2.5 2 1 0 2 2 2 0 RING-like domain TPR_12 PF13424.1 ETO14673.1 - 1.4e-40 137.0 12.5 8.6e-15 54.4 0.9 4.0 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO14673.1 - 3.3e-24 83.4 21.5 5.4e-09 35.2 0.4 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO14673.1 - 3.3e-24 82.7 14.7 1.5e-07 30.7 0.2 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO14673.1 - 1.6e-23 81.8 0.0 1.9e-06 27.5 0.0 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO14673.1 - 5.6e-20 70.7 16.0 1.3e-08 34.3 1.7 3.8 2 1 2 4 4 4 4 TPR repeat TPR_8 PF13181.1 ETO14673.1 - 7.3e-18 62.9 24.3 5e-07 29.0 0.9 4.9 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO14673.1 - 8.1e-18 62.7 5.2 3.8e-06 26.3 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_6 PF13174.1 ETO14673.1 - 7.6e-10 38.5 3.0 0.053 13.9 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO14673.1 - 2.1e-09 37.7 0.0 0.023 15.3 0.0 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO14673.1 - 1.2e-08 34.4 15.9 0.036 14.2 0.0 5.5 5 1 0 5 5 4 3 Tetratricopeptide repeat Apc3 PF12895.2 ETO14673.1 - 3.2e-08 33.6 14.0 0.0015 18.6 5.4 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 ETO14673.1 - 6.7e-06 26.2 0.0 0.26 12.0 0.0 4.1 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO14673.1 - 1.1e-05 25.6 1.4 0.93 9.8 0.4 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_3 PF07720.7 ETO14673.1 - 7.5e-05 22.4 14.3 0.47 10.2 0.1 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat MIT PF04212.13 ETO14673.1 - 0.0057 16.5 10.7 1.5 8.7 0.4 4.1 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain SNAP PF14938.1 ETO14673.1 - 0.015 14.4 9.5 1.5 7.9 0.8 3.3 2 1 2 4 4 4 0 Soluble NSF attachment protein, SNAP Sel1 PF08238.7 ETO14673.1 - 0.28 11.8 7.9 8.8 7.1 0.1 4.3 4 0 0 4 4 4 0 Sel1 repeat PPR PF01535.15 ETO14673.1 - 0.31 11.1 10.3 10 6.3 0.0 5.1 6 0 0 6 6 5 0 PPR repeat TPR_21 PF09976.4 ETO14673.1 - 3.2 7.6 5.5 0.62 10.0 0.1 2.5 3 1 0 3 3 3 0 Tetratricopeptide repeat YL1 PF05764.8 ETO14674.1 - 0.0014 18.3 17.0 0.0014 18.2 11.8 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Nucleoplasmin PF03066.10 ETO14674.1 - 0.0033 16.9 3.4 0.0041 16.6 2.3 1.2 1 0 0 1 1 1 1 Nucleoplasmin DUF2796 PF10986.3 ETO14674.1 - 0.062 13.2 5.0 0.066 13.1 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Host_attach PF10116.4 ETO14674.1 - 0.17 12.0 9.1 1.3 9.2 0.0 2.0 2 0 0 2 2 2 0 Protein required for attachment to host cells MIP-T3 PF10243.4 ETO14674.1 - 0.27 9.6 24.5 0.29 9.5 17.0 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1510 PF07423.6 ETO14674.1 - 0.45 9.8 15.3 0.44 9.8 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 ETO14674.1 - 0.5 8.3 14.1 0.48 8.4 9.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Rab_eff_C PF04698.7 ETO14674.1 - 0.59 8.1 11.0 0.69 7.9 7.7 1.0 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus RNA_polI_A34 PF08208.6 ETO14674.1 - 0.62 9.7 28.9 0.74 9.4 20.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Vfa1 PF08432.5 ETO14674.1 - 0.68 9.9 18.9 0.79 9.7 13.1 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SspB PF04386.8 ETO14674.1 - 0.75 9.3 6.8 0.88 9.1 4.7 1.4 1 0 0 1 1 1 0 Stringent starvation protein B RR_TM4-6 PF06459.7 ETO14674.1 - 0.9 9.3 14.6 0.96 9.2 10.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 U79_P34 PF03064.11 ETO14674.1 - 1.3 8.4 18.6 1.3 8.4 12.9 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Peptidase_C37 PF05416.7 ETO14674.1 - 1.3 7.1 11.1 1.4 7.0 7.7 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase GAGA_bind PF06217.7 ETO14674.1 - 1.6 8.6 16.3 1.7 8.5 11.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RNase_H2-Ydr279 PF09468.5 ETO14674.1 - 1.7 7.7 17.3 1.9 7.6 12.0 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DDHD PF02862.12 ETO14674.1 - 1.7 8.3 14.2 1.8 8.3 9.8 1.0 1 0 0 1 1 1 0 DDHD domain NARP1 PF12569.3 ETO14674.1 - 2.9 6.5 19.3 3.3 6.3 13.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FLO_LFY PF01698.11 ETO14674.1 - 6.7 5.4 15.1 7.3 5.3 10.4 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Herpes_DNAp_acc PF04929.7 ETO14674.1 - 6.8 5.5 15.0 7.7 5.3 10.4 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Serinc PF03348.10 ETO14674.1 - 6.9 5.2 6.2 6.9 5.2 4.3 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Raftlin PF15250.1 ETO14674.1 - 7.2 5.0 11.8 8.2 4.8 8.2 1.0 1 0 0 1 1 1 0 Raftlin Peptidase_U57 PF05582.7 ETO14674.1 - 7.4 5.4 10.5 8.4 5.2 7.3 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Sec62 PF03839.11 ETO14674.1 - 8.5 5.7 18.2 8.8 5.6 12.6 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Tom37_C PF11801.3 ETO14674.1 - 8.6 6.1 10.7 10 5.9 7.4 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain AAA_11 PF13086.1 ETO14674.1 - 9.2 5.7 11.1 11 5.5 7.7 1.1 1 0 0 1 1 1 0 AAA domain PBP1_TM PF14812.1 ETO14676.1 - 0.0034 17.6 0.4 0.0034 17.6 0.3 2.0 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 ETO14676.1 - 0.03 14.5 2.4 0.03 14.5 1.6 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Sporozoite_P67 PF05642.6 ETO14676.1 - 0.24 9.2 1.7 0.26 9.1 1.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RXT2_N PF08595.6 ETO14676.1 - 3 7.6 7.9 0.17 11.6 1.3 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal Spt5_N PF11942.3 ETO14676.1 - 6.3 7.4 15.5 1.1 9.9 6.0 2.1 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Nucleotid_trans PF03407.11 ETO14677.1 - 0.00011 22.0 0.1 0.00016 21.5 0.1 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF908 PF06012.7 ETO14678.1 - 0.037 13.3 0.6 0.04 13.2 0.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) zf-C2H2_4 PF13894.1 ETO14680.1 - 8.4e-11 41.4 51.9 0.0011 19.1 1.1 7.1 6 2 1 7 7 7 5 C2H2-type zinc finger zf-C2H2 PF00096.21 ETO14680.1 - 0.0042 17.3 64.5 0.02 15.2 1.9 7.8 7 1 0 7 7 7 5 Zinc finger, C2H2 type GTP_EFTU PF00009.22 ETO14681.1 - 6.7e-21 74.5 0.0 7.9e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DAHP_synth_1 PF00793.15 ETO14681.1 - 0.016 13.9 0.0 0.019 13.6 0.0 1.1 1 0 0 1 1 1 0 DAHP synthetase I family GTP_EFTU_D2 PF03144.20 ETO14682.1 - 1.5e-05 25.0 0.0 9.7e-05 22.4 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 ETO14682.1 - 0.0069 16.2 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Elongation Factor G, domain II Gag_p10 PF02337.12 ETO14682.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral GAG p10 protein EFG_IV PF03764.13 ETO14683.1 - 1.5e-26 92.2 0.0 2.3e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 ETO14683.1 - 5.8e-22 77.3 0.0 9.4e-22 76.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus DUF4446 PF14584.1 ETO14684.1 - 0.017 14.9 5.9 0.19 11.5 0.6 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) RGS PF00615.14 ETO14684.1 - 0.97 9.5 6.8 0.35 10.9 0.9 2.7 3 0 0 3 3 3 0 Regulator of G protein signaling domain Conotoxin PF02950.12 ETO14684.1 - 3.6 8.4 7.2 11 6.8 0.0 3.7 2 1 0 2 2 2 0 Conotoxin HECT PF00632.20 ETO14685.1 - 3.7e-74 249.7 0.1 8.4e-74 248.5 0.1 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 ETO14685.1 - 7.6e-14 51.8 0.4 1.9e-13 50.5 0.3 1.7 1 0 0 1 1 1 1 SPRY domain Laminin_G_3 PF13385.1 ETO14685.1 - 6.6e-09 36.2 0.3 1.5e-08 34.9 0.2 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily SR-25 PF10500.4 ETO14686.1 - 0.011 15.2 5.9 0.011 15.2 4.1 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 ETO14686.1 - 0.11 12.5 38.9 0.032 14.2 4.6 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF755) ARF7EP_C PF14949.1 ETO14686.1 - 1.6 9.1 20.9 3.8 7.9 2.2 3.3 3 0 0 3 3 3 0 ARF7 effector protein C-terminus BLVR PF06375.6 ETO14686.1 - 2.2 8.1 30.2 3.9 7.2 3.7 3.2 3 0 0 3 3 3 0 Bovine leukaemia virus receptor (BLVR) DUF1168 PF06658.7 ETO14686.1 - 3.1 7.3 31.1 1.7 8.1 6.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1168) DUF1754 PF08555.5 ETO14686.1 - 3.4 8.3 29.3 0.98 10.0 4.0 3.3 3 0 0 3 3 3 0 Eukaryotic family of unknown function (DUF1754) DUF3574 PF12098.3 ETO14689.1 - 0.096 12.2 0.2 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) Trypsin PF00089.21 ETO14690.1 - 1.9e-14 53.8 0.0 2.2e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Trypsin CDC45 PF02724.9 ETO14692.1 - 0.012 13.7 4.3 0.016 13.3 2.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Aconitase PF00330.15 ETO14693.1 - 0.067 11.6 0.2 0.082 11.3 0.2 1.0 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) DUF2457 PF10446.4 ETO14696.1 - 0.0001 21.2 18.4 0.00014 20.7 12.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) CDC45 PF02724.9 ETO14696.1 - 0.0067 14.5 9.5 0.0091 14.0 6.6 1.1 1 0 0 1 1 1 1 CDC45-like protein CENP-N PF05238.8 ETO14696.1 - 0.015 14.3 2.5 0.023 13.7 1.8 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like SDA1 PF05285.7 ETO14696.1 - 0.019 14.2 12.2 0.025 13.8 8.5 1.2 1 0 0 1 1 1 0 SDA1 Vfa1 PF08432.5 ETO14696.1 - 0.033 14.2 10.3 0.052 13.5 7.1 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Sigma70_ner PF04546.8 ETO14696.1 - 0.075 12.6 13.7 0.13 11.8 9.5 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 ETO14696.1 - 0.13 11.7 17.2 0.22 11.0 11.9 1.5 1 0 0 1 1 1 0 Nucleoplasmin DUF1510 PF07423.6 ETO14696.1 - 0.29 10.4 15.3 0.44 9.8 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Daxx PF03344.10 ETO14696.1 - 0.47 8.8 21.5 0.68 8.3 14.9 1.1 1 0 0 1 1 1 0 Daxx Family Cwf_Cwc_15 PF04889.7 ETO14696.1 - 0.91 9.1 16.1 1.3 8.7 11.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CobT PF06213.7 ETO14696.1 - 1.5 7.9 17.6 2.4 7.2 12.2 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Prog_receptor PF02161.10 ETO14696.1 - 2.3 6.9 6.4 3.2 6.4 4.5 1.1 1 0 0 1 1 1 0 Progesterone receptor zf-UBP PF02148.14 ETO14697.1 - 0.0019 18.2 0.1 0.0045 17.0 0.0 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein YjgP_YjgQ PF03739.9 ETO14697.1 - 0.094 11.4 0.6 0.14 10.8 0.4 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF3692 PF12469.3 ETO14698.1 - 0.0012 19.0 0.1 0.0023 18.1 0.0 1.4 1 0 0 1 1 1 1 CRISPR-associated protein Annexin PF00191.15 ETO14699.1 - 2.5e-22 78.5 0.1 3.1e-05 23.7 0.1 4.4 4 0 0 4 4 4 4 Annexin DUF1539 PF07560.6 ETO14700.1 - 0.11 12.4 6.0 0.14 12.0 3.8 1.5 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1539) TOH_N PF12549.3 ETO14700.1 - 0.21 11.2 0.7 0.36 10.4 0.5 1.3 1 0 0 1 1 1 0 Tyrosine hydroxylase N terminal U1snRNP70_N PF12220.3 ETO14701.1 - 0.0068 16.7 3.2 0.0068 16.7 2.2 2.8 3 0 0 3 3 3 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RVT_3 PF13456.1 ETO14701.1 - 0.29 10.9 2.3 16 5.3 0.1 3.0 2 0 0 2 2 2 0 Reverse transcriptase-like PT PF04886.7 ETO14702.1 - 0.0023 17.1 19.6 0.0023 17.1 13.6 1.6 2 0 0 2 2 2 1 PT repeat DUF4448 PF14610.1 ETO14702.1 - 0.05 13.0 0.0 0.093 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) SKG6 PF08693.5 ETO14702.1 - 0.088 12.1 3.4 0.25 10.7 2.3 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain WD40 PF00400.27 ETO14705.1 - 2.7e-50 166.5 17.0 4.3e-10 39.0 0.2 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO14705.1 - 3.8e-13 48.4 2.6 0.00097 17.3 0.0 5.0 1 1 4 5 5 5 5 Nucleoporin Nup120/160 Kelch_1 PF01344.20 ETO14707.1 - 0.0042 16.6 0.0 0.17 11.4 0.0 2.7 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETO14707.1 - 0.11 12.7 0.7 1 9.6 0.0 2.7 3 1 0 3 3 3 0 Kelch motif Toxin_52 PF15605.1 ETO14708.1 - 0.055 13.3 0.2 0.11 12.3 0.0 1.5 2 0 0 2 2 2 0 Putative toxin 52 SpoIISA_toxin PF14171.1 ETO14709.1 - 2.1 7.5 9.4 2.1 7.5 6.5 1.0 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system PTEN_C2 PF10409.4 ETO14711.1 - 1.8e-13 50.3 1.9 3.6e-13 49.3 1.3 1.5 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Herpes_TK_C PF08465.5 ETO14711.1 - 0.081 12.4 0.1 0.4 10.2 0.0 2.1 2 0 0 2 2 2 0 Thymidine kinase from Herpesvirus C-terminal DUF106 PF01956.11 ETO14712.1 - 0.0028 17.2 6.3 0.0057 16.2 2.2 2.7 2 0 0 2 2 2 1 Integral membrane protein DUF106 Mem_trans PF03547.13 ETO14712.1 - 0.0028 15.9 4.8 0.068 11.4 0.3 2.4 2 0 0 2 2 2 2 Membrane transport protein OmpH PF03938.9 ETO14712.1 - 0.38 10.6 19.5 0.9 9.4 13.5 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Ctr PF04145.10 ETO14712.1 - 1.2 9.1 10.6 2 8.4 0.0 3.6 4 1 1 5 5 5 0 Ctr copper transporter family DUF3987 PF13148.1 ETO14712.1 - 2.8 6.3 11.5 4.7 5.6 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF4512 PF14975.1 ETO14712.1 - 3.1 8.7 15.7 3.5 8.5 0.8 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) DUF3038 PF11237.3 ETO14714.1 - 0.031 14.0 0.2 0.037 13.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) dUTPase_2 PF08761.6 ETO14714.1 - 0.038 14.0 0.3 0.049 13.7 0.2 1.3 1 0 0 1 1 1 0 dUTPase U-box PF04564.10 ETO14716.1 - 2.3e-06 27.4 0.5 1e-05 25.4 0.1 2.3 2 0 0 2 2 2 1 U-box domain CcdB PF01845.12 ETO14716.1 - 0.00057 19.7 1.0 0.0017 18.2 0.7 1.8 1 0 0 1 1 1 1 CcdB protein PspA_IM30 PF04012.7 ETO14716.1 - 0.0084 15.4 4.9 0.018 14.4 3.4 1.5 1 0 0 1 1 1 1 PspA/IM30 family DUF4200 PF13863.1 ETO14716.1 - 0.056 13.3 7.7 6.5 6.7 4.6 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Lys PF00062.15 ETO14716.1 - 0.16 11.9 4.8 0.26 11.2 0.8 2.9 3 0 0 3 3 3 0 C-type lysozyme/alpha-lactalbumin family SRP1_TIP1 PF00660.12 ETO14716.1 - 0.18 11.6 4.2 0.3 10.9 1.7 2.2 1 1 1 2 2 2 0 Seripauperin and TIP1 family DUF745 PF05335.8 ETO14716.1 - 1.2 8.6 4.5 2.6 7.5 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF3450 PF11932.3 ETO14716.1 - 6.2 6.0 14.7 1.2 8.3 1.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) AA_permease PF00324.16 ETO14719.1 - 7.8e-13 47.5 19.2 5.1e-11 41.5 7.0 2.0 1 1 1 2 2 2 2 Amino acid permease DUF2207 PF09972.4 ETO14719.1 - 4.1e-05 22.3 7.7 0.014 14.0 0.2 2.2 1 1 1 2 2 2 2 Predicted membrane protein (DUF2207) ABC2_membrane PF01061.19 ETO14719.1 - 0.0024 17.0 12.5 0.031 13.4 0.6 2.1 2 0 0 2 2 2 2 ABC-2 type transporter E1-E2_ATPase PF00122.15 ETO14719.1 - 0.088 11.8 0.9 0.24 10.3 0.1 1.9 2 0 0 2 2 2 0 E1-E2 ATPase DUF912 PF06024.7 ETO14719.1 - 0.49 10.4 0.0 0.49 10.4 0.0 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) HXXEE PF13787.1 ETO14719.1 - 0.92 9.8 0.0 0.92 9.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function with HXXEE motif DUF3671 PF12420.3 ETO14719.1 - 1.8 8.6 10.9 26 4.8 7.6 2.5 1 1 0 1 1 1 0 Protein of unknown function Ripply PF14998.1 ETO14721.1 - 0.036 14.1 0.7 0.061 13.4 0.5 1.3 1 0 0 1 1 1 0 Transcription Regulator PRCH PF03967.8 ETO14723.1 - 0.6 9.6 2.8 1.9 8.0 2.0 1.8 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region Glyco_hydro_53 PF07745.8 ETO14726.1 - 1.2e-28 99.8 0.0 1.3e-26 93.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 53 Defensin_3 PF08131.6 ETO14726.1 - 0.12 12.3 0.1 0.29 11.1 0.0 1.6 2 0 0 2 2 2 0 Defensin-like peptide family ubiquitin PF00240.18 ETO14727.1 - 3.1e-166 539.0 27.5 5.1e-33 112.2 0.4 5.2 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.3 ETO14727.1 - 1.5e-99 325.7 25.2 1.4e-19 69.5 0.4 5.3 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 ETO14727.1 - 2.6e-31 107.7 11.4 0.00015 21.9 0.1 6.7 5 5 0 5 5 5 5 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 ETO14727.1 - 3.1e-17 62.4 8.2 0.053 13.4 0.1 5.8 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 ETO14727.1 - 2.5e-15 56.4 3.1 0.41 10.8 0.0 5.4 1 1 4 5 5 5 5 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 ETO14727.1 - 2.3e-12 46.7 0.1 1.5 8.9 0.0 5.8 5 0 0 5 5 5 5 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 ETO14727.1 - 4.9e-12 45.5 9.5 0.79 9.6 0.0 5.4 5 0 0 5 5 5 5 GLUT4 regulating protein TUG USP7_C2 PF14533.1 ETO14727.1 - 2.3e-10 40.2 5.2 0.64 9.4 0.0 5.3 5 0 0 5 5 5 5 Ubiquitin-specific protease C-terminal eRF1_1 PF03463.10 ETO14727.1 - 3.5e-08 33.1 5.9 4.7 6.7 0.0 6.0 1 1 4 5 5 5 4 eRF1 domain 1 PI3K_rbd PF00794.13 ETO14727.1 - 5e-07 29.6 5.6 12 5.9 0.0 5.7 5 0 0 5 5 5 0 PI3-kinase family, ras-binding domain FlgD_ig PF13860.1 ETO14727.1 - 1.3e-05 24.8 5.1 27 4.5 0.0 5.3 5 0 0 5 5 5 0 FlgD Ig-like domain GABP-alpha PF11620.3 ETO14727.1 - 0.00022 21.1 11.2 0.57 10.2 0.2 5.4 5 0 0 5 5 5 1 GA-binding protein alpha chain DUF3379 PF11859.3 ETO14727.1 - 0.0005 19.3 1.6 14 4.7 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3379) FERM_N PF09379.5 ETO14727.1 - 0.0044 17.0 10.4 62 3.7 0.1 6.5 5 4 0 5 5 5 0 FERM N-terminal domain T4_deiodinase PF00837.12 ETO14728.1 - 2.7e-14 52.7 0.0 3e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Iodothyronine deiodinase DUF4394 PF14339.1 ETO14728.1 - 0.13 11.4 0.1 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4394) DUF3503 PF12011.3 ETO14728.1 - 0.17 11.5 1.1 0.19 11.4 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3503) SAP PF02037.22 ETO14729.1 - 1.3e-07 30.9 0.7 1.3e-07 30.9 0.5 2.2 2 0 0 2 2 2 1 SAP domain Ku_C PF03730.9 ETO14729.1 - 1.6e-05 25.3 0.4 1.6e-05 25.3 0.3 2.2 1 1 1 2 2 2 1 Ku70/Ku80 C-terminal arm SMN PF06003.7 ETO14729.1 - 0.54 9.3 6.7 5.5 6.0 0.0 2.1 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) DUF547 PF04784.9 ETO14731.1 - 0.0059 16.4 2.9 0.011 15.6 2.0 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF547 tRNA-synt_2c PF01411.14 ETO14733.1 - 2.8e-05 22.6 0.5 6.8e-05 21.3 0.1 1.8 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 ETO14733.1 - 9e-05 22.2 0.7 0.00022 21.0 0.1 2.0 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain PT PF04886.7 ETO14734.1 - 3.3e-34 115.9 792.9 3.5e-08 32.6 12.5 38.8 2 1 16 19 19 19 9 PT repeat Pirin PF02678.11 ETO14735.1 - 2.1e-06 27.5 0.4 6.2e-05 22.8 0.3 2.4 1 1 0 1 1 1 1 Pirin Pox_P4B PF03292.9 ETO14738.1 - 0.12 10.2 0.8 0.24 9.3 0.6 1.4 1 0 0 1 1 1 0 Poxvirus P4B major core protein DUF4446 PF14584.1 ETO14739.1 - 2.6 7.8 6.5 0.84 9.4 2.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) NDUF_B5 PF09781.4 ETO14739.1 - 5.7 6.1 9.6 12 5.1 6.6 1.5 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit Peptidase_S49_N PF08496.5 ETO14739.1 - 9.1 6.0 14.5 20 4.9 9.3 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal ApoC-I PF04691.7 ETO14740.1 - 0.12 12.0 3.1 7.1 6.4 0.3 2.3 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) DUF972 PF06156.8 ETO14740.1 - 0.17 12.2 22.8 0.42 10.9 4.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF1666 PF07891.7 ETO14740.1 - 1.2 8.5 14.1 0.43 9.9 2.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1666) Reo_sigmaC PF04582.7 ETO14740.1 - 1.5 7.9 5.8 1.7 7.7 4.0 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein CALCOCO1 PF07888.6 ETO14740.1 - 1.6 6.9 21.0 2.1 6.5 14.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Hormone_1 PF00103.15 ETO14740.1 - 1.9 7.8 12.6 2.9 7.1 7.0 1.9 1 1 1 2 2 2 0 Somatotropin hormone family DUF1917 PF08939.5 ETO14740.1 - 1.9 8.1 8.5 0.15 11.8 1.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1917) Spc7 PF08317.6 ETO14740.1 - 3.1 6.3 23.1 4.4 5.8 16.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Cache_2 PF08269.6 ETO14740.1 - 3.6 7.6 12.0 0.49 10.3 1.9 2.3 1 1 0 2 2 2 0 Cache domain Laminin_II PF06009.7 ETO14740.1 - 4.2 7.1 13.9 5.5 6.7 3.6 2.1 1 1 1 2 2 2 0 Laminin Domain II Syntaxin-6_N PF09177.6 ETO14740.1 - 5.6 7.4 14.3 13 6.2 8.2 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Prominin PF05478.6 ETO14740.1 - 7 4.0 13.9 7.5 3.9 9.6 1.1 1 0 0 1 1 1 0 Prominin Tweety PF04906.8 ETO14740.1 - 7.3 4.8 9.7 1.7 6.9 4.3 1.6 1 1 0 1 1 1 0 Tweety PEP-utilisers_N PF05524.8 ETO14740.1 - 8.8 6.1 11.9 20 5.0 6.6 2.3 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal DUF1387 PF07139.6 ETO14741.1 - 0.013 15.1 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) NKAIN PF05640.9 ETO14741.1 - 0.053 12.4 0.2 0.077 11.9 0.1 1.2 1 0 0 1 1 1 0 Na,K-Atpase Interacting protein DUF3278 PF11683.3 ETO14741.1 - 0.069 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) Daxx PF03344.10 ETO14743.1 - 1.7 7.0 30.6 2 6.7 21.2 1.0 1 0 0 1 1 1 0 Daxx Family DUF4175 PF13779.1 ETO14743.1 - 3.8 5.0 22.8 4.9 4.7 15.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) WD40 PF00400.27 ETO14744.1 - 4.2e-55 181.7 30.5 1.4e-11 43.7 0.9 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO14744.1 - 1.9e-10 39.5 8.2 0.0089 14.2 0.8 5.6 1 1 4 5 5 5 4 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO14744.1 - 0.00089 19.5 2.6 0.00089 19.5 1.8 2.9 2 1 0 2 2 2 1 TRAF-type zinc finger Helicase_C_2 PF13307.1 ETO14744.1 - 0.039 13.9 2.7 0.19 11.6 0.0 2.3 2 0 0 2 2 2 0 Helicase C-terminal domain ODV-E18 PF10717.4 ETO14745.1 - 0.024 14.0 0.1 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Glu-tRNAGln PF02686.10 ETO14745.1 - 0.033 13.9 0.1 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit Bap31 PF05529.7 ETO14745.1 - 0.05 13.0 0.1 0.05 13.0 0.1 2.0 2 1 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF3753 PF12575.3 ETO14746.1 - 0.036 13.8 2.8 1.4 8.7 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) Integrin_B_tail PF07965.7 ETO14746.1 - 0.15 12.4 2.4 1.7 9.1 0.3 2.3 2 0 0 2 2 2 0 Integrin beta tail domain Destabilase PF05497.7 ETO14746.1 - 0.16 12.0 4.2 0.049 13.7 0.9 1.6 1 1 0 1 1 1 0 Destabilase Peroxin-13_N PF04088.8 ETO14746.1 - 6 6.8 8.8 0.64 9.9 2.6 2.0 1 1 1 2 2 2 0 Peroxin 13, N-terminal region Imm5 PF14423.1 ETO14747.1 - 0.055 13.0 1.0 0.064 12.8 0.7 1.2 1 0 0 1 1 1 0 Immunity protein Imm5 TPR_11 PF13414.1 ETO14748.1 - 5.4e-19 67.6 14.9 1.6e-07 30.8 0.0 5.5 3 2 3 6 6 6 4 TPR repeat TPR_16 PF13432.1 ETO14748.1 - 4.8e-13 49.3 0.1 0.012 16.2 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO14748.1 - 1.4e-12 46.4 15.1 0.013 15.3 0.0 6.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 ETO14748.1 - 9.1e-11 41.9 1.5 0.068 13.5 0.0 4.5 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO14748.1 - 5.1e-10 39.0 0.1 0.57 10.9 0.0 5.8 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO14748.1 - 1e-09 37.8 6.1 0.07 13.3 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO14748.1 - 3.1e-08 33.4 8.9 0.0042 16.9 0.0 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO14748.1 - 1.8e-07 30.4 4.6 0.0032 17.1 0.0 5.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO14748.1 - 2.9e-07 29.7 7.9 0.12 12.0 0.1 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 ETO14748.1 - 3.7e-07 30.1 16.6 0.00025 21.1 2.6 4.1 2 2 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 ETO14748.1 - 4.5e-05 23.2 2.0 6.4 6.7 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO14748.1 - 0.00018 21.7 5.1 3.1 8.4 0.0 5.7 7 0 0 7 7 6 2 Tetratricopeptide repeat NARP1 PF12569.3 ETO14748.1 - 0.0013 17.6 10.0 0.014 14.1 2.4 2.6 2 1 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_20 PF14561.1 ETO14748.1 - 0.0021 18.1 0.1 0.12 12.4 0.0 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_3 PF07720.7 ETO14748.1 - 0.043 13.6 6.5 0.14 11.9 0.6 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Acyltransferase PF01553.16 ETO14748.1 - 0.085 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Acyltransferase Fis1_TPR_C PF14853.1 ETO14748.1 - 0.24 11.3 6.1 0.93 9.4 0.8 3.4 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Cys_rich_VLP PF14194.1 ETO14748.1 - 0.3 10.8 0.0 0.3 10.8 0.0 2.3 2 0 0 2 2 1 0 Cysteine-rich VLP TPR_10 PF13374.1 ETO14748.1 - 2.4 8.2 4.4 33 4.5 0.0 3.6 5 0 0 5 5 4 0 Tetratricopeptide repeat ATP-synt_DE PF00401.15 ETO14748.1 - 2.5 8.0 5.0 0.55 10.1 0.5 2.1 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain TPR_19 PF14559.1 ETO14749.1 - 3.9e-09 36.7 4.2 0.01 16.1 0.0 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO14749.1 - 1.9e-06 28.0 2.9 1.2 9.9 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO14749.1 - 2.7e-06 27.8 4.7 7.1e-05 23.3 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO14749.1 - 4.8e-05 22.9 21.0 0.0046 16.7 0.6 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO14749.1 - 5.4e-05 23.0 10.6 0.0052 16.6 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO14749.1 - 0.00041 19.9 0.2 0.00041 19.9 0.2 3.8 3 1 1 4 4 4 2 TPR repeat Fis1_TPR_C PF14853.1 ETO14749.1 - 0.0049 16.7 0.1 0.033 14.0 0.1 2.4 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.1 ETO14749.1 - 0.005 16.9 6.1 0.19 12.0 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETO14749.1 - 0.016 15.1 4.2 27 4.8 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETO14749.1 - 0.43 10.4 17.2 4.8 7.2 0.4 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETO14749.1 - 0.47 10.3 7.6 1 9.3 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO14749.1 - 1.5 9.4 8.2 13 6.5 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETO14749.1 - 6.1 6.6 16.6 7.6 6.3 0.5 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA PF00004.24 ETO14750.1 - 2e-08 34.4 0.1 1.9e-06 28.1 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETO14750.1 - 2.4e-06 27.3 0.1 1.3e-05 24.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 ETO14750.1 - 1e-05 25.4 1.5 7.1e-05 22.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 ETO14750.1 - 6.4e-05 23.7 0.0 0.0078 17.0 0.0 3.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETO14750.1 - 0.00017 21.9 0.1 0.00083 19.6 0.0 2.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 ETO14750.1 - 0.00019 21.7 0.0 0.00058 20.1 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 ETO14750.1 - 0.0015 18.5 0.0 0.24 11.3 0.0 3.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 ETO14750.1 - 0.0021 18.1 0.1 0.017 15.2 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_2 PF07724.9 ETO14750.1 - 0.0059 16.5 0.0 0.02 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 ETO14750.1 - 0.023 14.8 0.6 0.65 10.2 0.0 3.2 2 0 0 2 2 2 0 RNA helicase MCM PF00493.18 ETO14750.1 - 0.034 12.9 0.0 0.096 11.4 0.0 1.7 1 0 0 1 1 1 0 MCM2/3/5 family NTPase_1 PF03266.10 ETO14750.1 - 0.036 13.7 0.0 1.5 8.4 0.0 2.6 2 0 0 2 2 2 0 NTPase PH PF00169.24 ETO14751.1 - 2.5e-07 30.8 0.2 2.5e-07 30.8 0.1 2.6 2 1 0 2 2 2 1 PH domain UreF PF01730.11 ETO14751.1 - 0.0018 18.3 1.0 0.0054 16.8 0.3 1.9 2 0 0 2 2 2 1 UreF PH_11 PF15413.1 ETO14751.1 - 0.0032 17.6 0.1 0.0032 17.6 0.1 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain IncA PF04156.9 ETO14751.1 - 0.0061 16.1 16.2 0.015 14.8 11.3 1.7 1 0 0 1 1 1 1 IncA protein Reo_sigmaC PF04582.7 ETO14751.1 - 0.0084 15.3 3.2 0.014 14.6 2.2 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein ATG16 PF08614.6 ETO14751.1 - 0.064 13.0 27.2 0.027 14.2 16.5 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4200 PF13863.1 ETO14751.1 - 0.099 12.5 27.3 0.044 13.7 16.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) APG6 PF04111.7 ETO14751.1 - 0.19 10.7 19.5 0.41 9.6 13.5 1.6 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1700 PF08006.6 ETO14751.1 - 0.9 8.8 6.4 2.7 7.2 4.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) WD40 PF00400.27 ETO14752.1 - 4.6e-09 35.8 0.0 0.00026 20.7 0.0 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat Hid1 PF12722.2 ETO14752.1 - 8.3 3.9 13.7 11 3.5 9.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein WD40 PF00400.27 ETO14753.1 - 0.089 12.7 0.0 0.56 10.1 0.0 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat Acyltransferase PF01553.16 ETO14754.1 - 0.0013 18.1 0.0 0.0027 17.1 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Methyltransf_31 PF13847.1 ETO14754.1 - 0.071 12.7 0.0 0.32 10.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Acyltransferase PF01553.16 ETO14755.1 - 0.00054 19.4 0.0 0.00089 18.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Methyltransf_31 PF13847.1 ETO14755.1 - 0.014 15.0 0.0 0.1 12.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain SART-1 PF03343.8 ETO14756.1 - 7.9e-06 24.5 33.7 7.9e-06 24.5 23.4 2.1 2 0 0 2 2 2 1 SART-1 family IncA PF04156.9 ETO14756.1 - 10 5.6 22.7 3.5 7.1 1.7 2.7 2 0 0 2 2 2 0 IncA protein Nop14 PF04147.7 ETO14758.1 - 0.00024 19.1 18.1 0.00024 19.1 12.6 1.1 1 0 0 1 1 1 1 Nop14-like family zf-C3HC4 PF00097.20 ETO14758.1 - 0.00068 19.2 3.1 0.0028 17.2 2.2 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CobT PF06213.7 ETO14758.1 - 0.0043 16.2 15.0 0.0053 15.9 10.4 1.2 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT CENP-T PF15511.1 ETO14758.1 - 0.0073 15.6 7.0 0.0072 15.6 4.8 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T zf-RING_2 PF13639.1 ETO14758.1 - 0.0083 15.9 4.0 0.0083 15.9 2.8 1.9 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 ETO14758.1 - 0.43 10.3 4.5 1.2 8.8 3.2 1.8 1 0 0 1 1 1 0 RING-type zinc-finger CDC45 PF02724.9 ETO14758.1 - 0.49 8.3 23.7 0.68 7.8 16.4 1.2 1 0 0 1 1 1 0 CDC45-like protein IBR PF01485.16 ETO14758.1 - 0.75 9.7 15.7 0.31 10.9 0.5 3.4 2 1 1 3 3 3 0 IBR domain DUF1510 PF07423.6 ETO14758.1 - 2.6 7.3 25.7 0.65 9.3 15.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF3439 PF11921.3 ETO14759.1 - 0.02 14.6 6.8 0.042 13.6 4.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 ETO14759.1 - 0.022 14.5 16.6 0.041 13.6 11.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.6 ETO14759.1 - 0.54 8.1 11.5 0.73 7.7 8.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF190 PF02641.10 ETO14759.1 - 0.54 10.1 5.0 0.21 11.4 0.8 2.3 2 0 0 2 2 2 0 Uncharacterized ACR, COG1993 DUF2778 PF10908.3 ETO14761.1 - 1.2e-05 25.4 0.5 0.00011 22.4 0.3 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2778) PcfK PF14058.1 ETO14761.1 - 0.05 13.7 0.4 0.073 13.2 0.2 1.4 1 1 0 1 1 1 0 PcfK-like protein YkuD PF03734.9 ETO14761.1 - 0.078 13.2 0.5 0.1 12.8 0.4 1.3 1 1 0 1 1 1 0 L,D-transpeptidase catalytic domain RelA_SpoT PF04607.12 ETO14762.1 - 0.029 14.3 2.0 0.046 13.7 1.3 1.4 1 1 0 1 1 1 0 Region found in RelA / SpoT proteins Aminotran_1_2 PF00155.16 ETO14763.1 - 7.8e-37 127.0 0.0 1e-36 126.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.8 ETO14763.1 - 0.00018 20.2 0.1 0.00032 19.4 0.1 1.4 1 1 0 1 1 1 1 Allinase DUF2431 PF10354.4 ETO14763.1 - 0.089 12.7 0.5 0.29 11.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2431) YajC PF02699.10 ETO14764.1 - 0.36 10.5 2.6 0.5 10.0 0.3 2.0 2 0 0 2 2 2 0 Preprotein translocase subunit Peptidase_M18 PF02127.10 ETO14765.1 - 6.4e-45 153.4 0.2 2.1e-42 145.1 0.1 2.0 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M18 PF02127.10 ETO14766.1 - 3.2e-54 184.0 0.1 3.6e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 ETO14766.1 - 1.9e-08 33.4 0.0 2.3e-08 33.1 0.0 1.0 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase NAD_binding_8 PF13450.1 ETO14767.1 - 2.4e-11 43.4 0.4 6.4e-11 42.1 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETO14767.1 - 3.3e-06 26.2 0.0 4.5e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 ETO14767.1 - 7.1e-06 25.3 0.0 1.5e-05 24.2 0.0 1.5 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 ETO14767.1 - 0.00015 22.1 0.0 0.00031 21.1 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETO14767.1 - 0.0011 18.7 0.0 0.0026 17.5 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 ETO14767.1 - 0.0083 16.0 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 ETO14767.1 - 0.051 12.6 0.0 0.087 11.8 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.19 ETO14767.1 - 0.093 11.5 0.0 0.2 10.4 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain DUF2922 PF11148.3 ETO14768.1 - 0.022 14.4 0.3 0.035 13.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) DNA_pol_B PF00136.16 ETO14768.1 - 0.042 12.6 0.4 0.045 12.5 0.3 1.1 1 0 0 1 1 1 0 DNA polymerase family B IF3_C PF00707.17 ETO14768.1 - 0.043 13.5 1.4 0.067 12.9 1.0 1.2 1 0 0 1 1 1 0 Translation initiation factor IF-3, C-terminal domain PRP1_N PF06424.7 ETO14768.1 - 0.23 11.7 2.6 0.32 11.3 1.8 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Orthopox_35kD PF02250.10 ETO14769.1 - 0.00028 20.2 0.8 0.0013 18.0 0.1 2.0 1 1 1 2 2 2 1 35kD major secreted virus protein MMS19_C PF12460.3 ETO14769.1 - 0.017 13.8 0.9 0.019 13.7 0.6 1.1 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal Pantoate_ligase PF02569.10 ETO14769.1 - 0.052 12.3 0.0 0.055 12.2 0.0 1.2 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase DUF137 PF02006.11 ETO14769.1 - 0.061 12.6 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF137 FoP_duplication PF13865.1 ETO14770.1 - 1.8e-06 28.2 13.7 1.8e-06 28.2 9.5 3.2 1 1 2 3 3 3 2 C-terminal duplication domain of Friend of PRMT1 Zip PF02535.17 ETO14770.1 - 0.19 10.7 1.0 0.25 10.3 0.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Filo_glycop PF01611.11 ETO14770.1 - 0.19 10.5 4.6 0.26 10.0 3.2 1.2 1 0 0 1 1 1 0 Filovirus glycoprotein DDHD PF02862.12 ETO14770.1 - 0.9 9.2 6.8 1.2 8.9 4.7 1.2 1 0 0 1 1 1 0 DDHD domain UxaC PF02614.9 ETO14771.1 - 0.021 13.4 2.1 0.026 13.1 1.5 1.0 1 0 0 1 1 1 0 Glucuronate isomerase DARPP-32 PF05395.7 ETO14772.1 - 0.05 13.7 0.3 0.063 13.4 0.2 1.1 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 FAM60A PF15396.1 ETO14772.1 - 0.11 12.2 3.4 0.14 11.9 2.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A APP_E2 PF12925.2 ETO14772.1 - 0.15 11.5 5.7 0.1 12.1 2.3 1.8 1 1 1 2 2 2 0 E2 domain of amyloid precursor protein Vma12 PF11712.3 ETO14773.1 - 0.00081 19.1 1.3 0.00081 19.1 0.9 1.6 1 1 1 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2207 PF09972.4 ETO14773.1 - 0.0094 14.5 8.3 0.013 14.1 5.8 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Neur_chan_memb PF02932.11 ETO14773.1 - 0.034 14.0 1.6 0.048 13.5 1.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GAGA_bind PF06217.7 ETO14773.1 - 0.042 13.8 9.8 0.049 13.5 6.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3464 PF11947.3 ETO14773.1 - 0.048 13.1 5.2 0.076 12.4 3.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF4337 PF14235.1 ETO14773.1 - 0.47 10.2 3.1 0.63 9.8 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) RNA_pol_Rpb1_5 PF04998.12 ETO14773.1 - 1.2 8.2 6.2 1.4 8.0 4.3 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Vfa1 PF08432.5 ETO14773.1 - 1.3 9.0 20.0 1.9 8.5 13.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF912 PF06024.7 ETO14773.1 - 3.4 7.7 8.8 3.4 7.7 3.5 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DDHD PF02862.12 ETO14773.1 - 4 7.1 8.3 5.4 6.7 5.7 1.1 1 0 0 1 1 1 0 DDHD domain Peroxin-13_N PF04088.8 ETO14773.1 - 6.2 6.7 9.8 13 5.7 6.8 1.6 1 1 0 1 1 1 0 Peroxin 13, N-terminal region RNase_H2-Ydr279 PF09468.5 ETO14773.1 - 6.7 5.8 20.2 9.3 5.3 14.0 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) RR_TM4-6 PF06459.7 ETO14773.1 - 7.4 6.3 12.5 12 5.7 8.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2413 PF10310.4 ETO14773.1 - 7.9 5.1 15.6 10 4.7 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Kelch_6 PF13964.1 ETO14774.1 - 2e-11 43.5 7.0 4.3e-06 26.6 0.0 4.5 4 1 1 5 5 5 3 Kelch motif Kelch_1 PF01344.20 ETO14774.1 - 1.1e-10 40.8 7.2 2.3e-05 23.8 0.0 4.6 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.1 ETO14774.1 - 3.1e-09 36.5 0.0 0.0034 17.3 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Peptidase_C14 PF00656.17 ETO14774.1 - 5.3e-09 36.1 0.6 1.2e-08 35.0 0.4 1.6 1 1 0 1 1 1 1 Caspase domain Kelch_3 PF13415.1 ETO14774.1 - 2.8e-06 27.3 0.2 0.00012 22.1 0.0 3.0 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO14774.1 - 0.00011 21.9 0.2 0.026 14.3 0.0 2.9 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO14774.1 - 0.00016 21.3 1.1 1.2 8.9 0.0 5.0 5 0 0 5 5 5 1 Kelch motif Lebercilin PF15619.1 ETO14774.1 - 0.14 11.5 0.0 0.29 10.5 0.0 1.5 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF2890 PF11081.3 ETO14775.1 - 0.12 12.4 0.1 0.17 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) SNF2_N PF00176.18 ETO14776.1 - 1.1e-63 214.8 0.5 1.5e-63 214.4 0.3 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETO14776.1 - 1.1e-13 50.8 0.0 3.6e-13 49.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 ETO14776.1 - 4.4e-07 29.0 1.0 4.4e-07 29.0 0.7 2.3 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 BSP_II PF05432.6 ETO14776.1 - 0.074 12.3 6.4 0.13 11.5 4.4 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF3245 PF11595.3 ETO14776.1 - 0.65 10.2 7.6 1.9 8.7 5.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3245) DUF2457 PF10446.4 ETO14776.1 - 0.87 8.2 10.6 1.4 7.5 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ribosomal_60s PF00428.14 ETO14776.1 - 6.1 7.3 9.4 16 5.9 6.5 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein PHD PF00628.24 ETO14777.1 - 0.0001 21.9 7.1 0.0001 21.9 4.9 2.2 2 0 0 2 2 2 1 PHD-finger PHF5 PF03660.9 ETO14777.1 - 0.018 15.1 0.9 0.046 13.7 0.7 1.7 1 0 0 1 1 1 0 PHF5-like protein PHD_2 PF13831.1 ETO14777.1 - 0.64 9.3 11.5 0.073 12.3 3.1 2.8 1 1 1 2 2 2 0 PHD-finger UAA PF08449.6 ETO14778.1 - 3.3e-51 173.9 24.4 5.7e-38 130.5 7.6 2.7 3 0 0 3 3 3 2 UAA transporter family EamA PF00892.15 ETO14778.1 - 0.0022 18.0 0.3 0.0022 18.0 0.2 4.6 6 0 0 6 6 6 2 EamA-like transporter family TPT PF03151.11 ETO14778.1 - 0.0085 15.7 5.2 0.0085 15.7 3.6 4.1 5 0 0 5 5 5 2 Triose-phosphate Transporter family DUF2955 PF11168.3 ETO14778.1 - 6.3 6.4 18.3 0.089 12.4 2.4 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2955) Arm PF00514.18 ETO14780.1 - 2.8e-33 112.5 4.9 2.3e-08 33.5 0.1 7.2 8 0 0 8 8 8 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 ETO14780.1 - 3e-14 53.0 0.0 5.8e-07 29.7 0.0 4.3 2 2 3 5 5 5 4 HEAT repeats HEAT_EZ PF13513.1 ETO14780.1 - 9.5e-10 38.6 0.0 0.2 12.2 0.0 4.8 4 0 0 4 4 4 3 HEAT-like repeat HEAT PF02985.17 ETO14780.1 - 0.00056 19.7 2.0 0.45 10.7 0.0 4.4 5 0 0 5 5 5 1 HEAT repeat UPF0147 PF03685.8 ETO14780.1 - 0.1 12.4 1.7 21 5.0 0.0 3.7 5 0 0 5 5 5 0 Uncharacterised protein family (UPF0147) AMP-binding PF00501.23 ETO14781.1 - 3.2e-22 78.5 0.1 1.1e-21 76.7 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETO14781.1 - 3.8e-08 34.1 0.0 6.2e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Kelch_6 PF13964.1 ETO14782.1 - 4.9e-10 39.1 3.3 0.0003 20.8 0.1 4.6 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.1 ETO14782.1 - 5.8e-10 38.7 0.1 0.00031 20.4 0.0 4.3 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO14782.1 - 1.4e-07 30.8 2.0 0.0064 16.0 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO14782.1 - 4.6e-07 29.3 1.8 0.005 16.5 0.1 4.4 4 1 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO14782.1 - 3.4e-05 23.6 0.0 0.048 13.6 0.0 4.1 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 ETO14782.1 - 0.0043 17.1 0.0 0.1 12.7 0.0 3.2 4 0 0 4 4 4 1 Galactose oxidase, central domain TraL PF07178.6 ETO14783.1 - 0.0075 16.2 2.3 0.0075 16.2 1.6 2.3 1 1 1 2 2 2 1 TraL protein DUF2663 PF10864.3 ETO14783.1 - 4.4 7.5 7.9 1.5 9.0 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2663) Striatin PF08232.7 ETO14784.1 - 1 9.6 13.4 1.3 9.3 4.1 2.2 2 0 0 2 2 2 0 Striatin family NPR3 PF03666.8 ETO14784.1 - 6 5.2 12.0 2 6.8 2.8 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Gag_spuma PF03276.9 ETO14784.1 - 6.7 4.9 12.5 8.3 4.6 8.7 1.3 1 0 0 1 1 1 0 Spumavirus gag protein TPR_12 PF13424.1 ETO14786.1 - 1.3e-53 178.8 13.6 6e-18 64.5 2.0 4.2 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO14786.1 - 1.6e-32 110.9 19.5 5.9e-13 48.2 0.4 4.3 4 0 0 4 4 4 3 TPR repeat TPR_10 PF13374.1 ETO14786.1 - 1.7e-30 103.9 0.0 6.5e-08 32.2 0.0 6.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.23 ETO14786.1 - 2.2e-30 102.9 34.0 5.1e-08 32.1 0.7 6.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.1 ETO14786.1 - 9.8e-27 90.6 4.7 4.7e-05 22.8 0.0 6.0 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETO14786.1 - 1.5e-23 80.7 21.9 1.7e-06 27.4 0.3 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO14786.1 - 4.6e-22 76.0 34.4 1.3e-06 27.7 0.6 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.1 ETO14786.1 - 9.1e-10 37.9 13.9 0.075 13.2 0.3 6.9 6 0 0 6 6 6 3 Tetratricopeptide repeat DUF2225 PF09986.4 ETO14786.1 - 5.4e-05 22.7 16.6 0.054 12.9 0.5 4.0 1 1 2 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_14 PF13428.1 ETO14786.1 - 8.4e-05 22.8 0.0 7.2 7.5 0.0 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO14786.1 - 0.00016 22.2 0.0 1.4 9.6 0.0 4.3 3 2 0 4 4 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO14786.1 - 0.017 14.3 0.9 9.4 5.5 0.0 4.2 5 0 0 5 5 5 0 SHNi-TPR TPR_3 PF07720.7 ETO14786.1 - 0.035 13.8 0.9 0.035 13.8 0.6 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO14786.1 - 0.089 13.2 5.3 6.2 7.5 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat MIT PF04212.13 ETO14786.1 - 0.12 12.2 12.7 0.5 10.2 0.1 4.7 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain DUF627 PF04781.7 ETO14786.1 - 0.17 11.5 4.6 2.7 7.6 0.0 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF627) Pkinase PF00069.20 ETO14788.1 - 3.1e-37 128.1 0.0 1.1e-24 86.9 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO14788.1 - 1.4e-24 86.5 0.0 3.2e-17 62.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase SelP_N PF04592.9 ETO14788.1 - 0.068 12.5 11.2 0.1 11.9 7.7 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 ETO14788.1 - 0.071 12.1 2.0 0.086 11.8 1.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Pkinase PF00069.20 ETO14789.1 - 0.0027 16.8 1.3 0.0035 16.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain DUF3595 PF12166.3 ETO14789.1 - 9.2 4.9 14.5 13 4.4 10.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) Phage_lambda_P PF06992.6 ETO14790.1 - 0.012 14.9 0.1 0.023 14.0 0.1 1.4 1 0 0 1 1 1 0 Replication protein P DUF4339 PF14237.1 ETO14792.1 - 5.4e-06 25.8 0.3 1.7e-05 24.2 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4339) Metallophos PF00149.23 ETO14793.1 - 7.3e-37 126.7 0.1 5.8e-18 65.0 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Ank_2 PF12796.2 ETO14794.1 - 0.0015 18.8 0.0 0.019 15.2 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO14794.1 - 0.064 13.7 0.1 1.4 9.5 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeats (many copies) LRR_4 PF12799.2 ETO14795.1 - 0.00093 18.7 1.1 0.0021 17.6 0.7 1.6 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.7 ETO14795.1 - 0.0029 17.5 0.1 0.0053 16.6 0.1 1.5 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.28 ETO14795.1 - 0.039 13.9 0.6 0.22 11.6 0.1 2.5 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_4 PF12799.2 ETO14796.1 - 2.3e-17 62.1 16.9 0.00017 21.1 1.2 4.9 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO14796.1 - 1e-13 50.8 34.8 7.1e-07 28.8 1.3 3.2 1 1 4 5 5 5 5 Leucine rich repeat LRR_1 PF00560.28 ETO14796.1 - 3.3e-11 41.6 9.1 0.03 14.2 0.1 5.4 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.1 ETO14796.1 - 1.8e-05 24.2 9.8 0.066 13.3 0.1 4.6 2 2 1 3 3 3 2 Leucine Rich repeat LRR_7 PF13504.1 ETO14796.1 - 8.5e-05 22.1 6.3 2.7 8.5 0.1 4.9 5 0 0 5 5 5 1 Leucine rich repeat CheY-binding PF09078.6 ETO14796.1 - 0.14 12.1 0.1 3.9 7.5 0.0 2.7 2 1 1 3 3 3 0 CheY binding FNIP PF05725.7 ETO14796.1 - 5.2 7.1 12.7 12 5.9 2.1 3.9 2 2 1 3 3 3 0 FNIP Repeat DNA_ligase_A_M PF01068.16 ETO14798.1 - 3.4e-19 69.0 0.2 7.8e-19 67.8 0.1 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.10 ETO14798.1 - 2.8e-15 56.4 0.0 6.6e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 ETO14798.1 - 1.3e-09 38.0 2.1 9.4e-05 22.4 0.1 3.2 3 1 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.3 ETO14798.1 - 0.00016 21.3 0.4 0.00032 20.3 0.3 1.6 1 0 0 1 1 1 1 DNA ligase IV PTCB-BRCT PF12738.2 ETO14798.1 - 0.00039 20.2 0.0 0.41 10.5 0.0 2.7 2 0 0 2 2 2 2 twin BRCT domain mRNA_cap_enzyme PF01331.14 ETO14798.1 - 0.0018 18.0 0.0 0.0049 16.5 0.0 1.7 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain Phos_pyr_kin PF08543.7 ETO14798.1 - 0.12 11.5 0.0 0.42 9.7 0.0 1.8 2 0 0 2 2 2 0 Phosphomethylpyrimidine kinase RP-C_C PF11800.3 ETO14798.1 - 0.38 10.4 1.6 0.8 9.3 1.1 1.5 1 0 0 1 1 1 0 Replication protein C C-terminal region DNA_ligase_A_N PF04675.9 ETO14799.1 - 7.5e-31 107.3 0.0 1.4e-30 106.3 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.16 ETO14799.1 - 3e-15 56.1 1.0 3e-15 56.1 0.7 1.8 2 0 0 2 2 2 1 ATP dependent DNA ligase domain His_kinase PF06580.8 ETO14799.1 - 0.55 10.1 7.3 0.16 11.8 0.3 3.4 3 1 1 4 4 4 0 Histidine kinase Metallophos_2 PF12850.2 ETO14800.1 - 1.5e-18 67.1 0.0 1.8e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 ETO14800.1 - 0.0017 17.8 1.0 0.0077 15.6 0.7 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase IRK PF01007.15 ETO14801.1 - 9.9e-17 60.7 0.0 1.2e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel DUF596 PF04591.7 ETO14801.1 - 0.21 11.5 0.8 3.1 7.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF596 Treacle PF03546.9 ETO14802.1 - 0.018 13.8 0.7 0.027 13.2 0.5 1.3 1 0 0 1 1 1 0 Treacher Collins syndrome protein Treacle WD40 PF00400.27 ETO14803.1 - 2.4e-86 280.8 24.4 2.9e-13 49.1 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO14803.1 - 2.4e-08 32.6 8.9 0.11 10.6 0.0 5.8 1 1 6 7 7 7 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO14803.1 - 0.00011 20.5 0.8 0.65 8.2 0.0 3.4 1 1 2 4 4 4 2 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO14803.1 - 0.00021 20.5 2.9 3.2 6.7 0.0 4.9 2 1 3 6 6 6 2 Neuroblastoma-amplified sequence, N terminal Resistin PF06954.6 ETO14803.1 - 0.00029 21.0 1.0 0.73 10.1 0.0 5.3 2 1 5 7 7 7 1 Resistin PD40 PF07676.7 ETO14803.1 - 0.00031 20.3 14.1 6.7 6.4 0.1 6.1 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 ETO14803.1 - 0.0042 15.7 0.1 0.97 7.9 0.0 3.4 2 1 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Mid2 PF04478.7 ETO14803.1 - 0.13 11.6 2.1 3.9 6.8 0.0 3.7 3 2 2 5 5 5 0 Mid2 like cell wall stress sensor Proteasome_A_N PF10584.4 ETO14803.1 - 0.55 9.5 10.9 19 4.6 0.0 5.4 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature DUF241 PF03087.9 ETO14804.1 - 0.023 14.2 1.6 0.12 11.8 0.1 2.1 2 0 0 2 2 2 0 Arabidopsis protein of unknown function BING4CT PF08149.6 ETO14804.1 - 0.1 12.0 0.0 13 5.3 0.0 2.6 2 0 0 2 2 2 0 BING4CT (NUC141) domain Enolase_N PF03952.11 ETO14805.1 - 7.6e-24 84.1 0.1 1.8e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 Enolase, N-terminal domain RGS PF00615.14 ETO14805.1 - 3.3e-23 82.0 2.7 3.3e-23 82.0 0.6 2.0 2 0 0 2 2 2 1 Regulator of G protein signaling domain cNMP_binding PF00027.24 ETO14805.1 - 0.0011 18.6 0.0 0.38 10.5 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain GCC2_GCC3 PF07699.8 ETO14806.1 - 0.26 10.9 2.7 0.59 9.7 0.1 2.3 2 0 0 2 2 2 0 GCC2 and GCC3 Enolase_C PF00113.17 ETO14807.1 - 1.7e-100 335.8 0.1 1.9e-100 335.6 0.1 1.0 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain MAAL_C PF07476.6 ETO14807.1 - 1.9e-05 23.7 0.2 2.6e-05 23.2 0.2 1.1 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_C PF13378.1 ETO14807.1 - 0.00012 22.0 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like Enolase_C PF00113.17 ETO14808.1 - 5.3e-31 107.6 1.3 5.8e-30 104.2 0.9 2.0 1 1 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 ETO14808.1 - 1.4e-16 60.6 0.0 2.3e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain DUF2631 PF10939.3 ETO14808.1 - 0.14 12.0 0.2 0.3 10.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2631) BAF1_ABF1 PF04684.8 ETO14809.1 - 0.038 12.8 5.6 0.056 12.2 3.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4483 PF14825.1 ETO14810.1 - 0.055 13.1 0.5 0.072 12.7 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4483) RasGAP PF00616.14 ETO14812.1 - 9e-28 97.2 5.6 9.5e-28 97.2 3.0 1.7 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase BAF1_ABF1 PF04684.8 ETO14813.1 - 0.38 9.5 15.6 0.7 8.6 10.8 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor XAP5 PF04921.9 ETO14813.1 - 1.1 8.7 22.1 0.026 14.0 8.7 2.1 2 0 0 2 2 2 0 XAP5, circadian clock regulator RAB3GAP2_N PF14655.1 ETO14814.1 - 0.00016 20.8 0.9 0.00025 20.1 0.6 1.4 1 1 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus TP6A_N PF04406.9 ETO14814.1 - 0.42 10.3 3.3 6.6 6.4 1.3 2.4 2 0 0 2 2 2 0 Type IIB DNA topoisomerase fn3 PF00041.16 ETO14818.1 - 9e-07 28.9 1.4 0.14 12.3 0.0 3.5 3 0 0 3 3 3 2 Fibronectin type III domain tRNA_anti_2 PF13742.1 ETO14818.1 - 0.019 14.8 0.0 0.51 10.2 0.0 2.4 1 1 1 2 2 2 0 OB-fold nucleic acid binding domain Pga1 PF10333.4 ETO14818.1 - 0.099 12.2 2.2 0.88 9.1 0.2 2.3 2 0 0 2 2 2 0 GPI-Mannosyltransferase II co-activator KH_1 PF00013.24 ETO14818.1 - 0.39 10.3 3.1 0.28 10.8 0.5 2.0 2 0 0 2 2 2 0 KH domain ALG3 PF05208.8 ETO14820.1 - 0.035 13.3 0.0 0.041 13.1 0.0 1.1 1 0 0 1 1 1 0 ALG3 protein GP120 PF00516.13 ETO14820.1 - 0.056 11.6 0.1 0.061 11.5 0.1 1.1 1 0 0 1 1 1 0 Envelope glycoprotein GP120 IncA PF04156.9 ETO14822.1 - 0.11 12.0 12.4 0.22 11.1 8.6 1.5 1 0 0 1 1 1 0 IncA protein BAAT_C PF08840.6 ETO14822.1 - 2.1 7.9 8.6 0.35 10.5 0.8 3.0 3 1 0 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal Fib_alpha PF08702.5 ETO14822.1 - 8.3 6.5 12.0 33 4.5 7.9 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ATHILA PF03078.10 ETO14823.1 - 0.0097 14.5 0.4 0.013 14.1 0.3 1.1 1 0 0 1 1 1 1 ATHILA ORF-1 family Tn7_Tnp_TnsA_N PF08722.6 ETO14823.1 - 0.064 13.2 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 TnsA endonuclease N terminal DUF2649 PF10854.3 ETO14825.1 - 0.19 11.8 2.5 0.35 11.0 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2649) Ras PF00071.17 ETO14826.1 - 7.4e-15 54.6 0.5 1.3e-12 47.4 0.4 2.1 1 1 0 1 1 1 1 Ras family Miro PF08477.8 ETO14826.1 - 1e-08 35.6 0.3 3.6e-08 33.9 0.0 2.0 1 1 1 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 ETO14826.1 - 0.014 14.5 1.1 0.027 13.5 0.2 1.9 1 1 1 2 2 2 0 Gtr1/RagA G protein conserved region Arf PF00025.16 ETO14826.1 - 0.018 14.2 0.2 0.067 12.4 0.0 1.9 1 1 1 3 3 3 0 ADP-ribosylation factor family zf-like PF04071.7 ETO14826.1 - 0.024 14.3 0.3 0.042 13.5 0.1 1.6 1 1 0 1 1 1 0 Cysteine-rich small domain DUF4578 PF15147.1 ETO14826.1 - 0.095 13.0 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4578) SAP PF02037.22 ETO14830.1 - 0.012 15.0 0.2 0.012 15.0 0.1 2.7 3 0 0 3 3 3 0 SAP domain SRP54_N PF02881.14 ETO14830.1 - 0.06 13.4 3.2 0.27 11.3 1.5 2.3 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain Sina PF03145.11 ETO14831.1 - 5.1e-06 26.2 13.8 2.4e-05 24.1 7.3 2.8 1 1 1 2 2 2 2 Seven in absentia protein family Kelch_6 PF13964.1 ETO14832.1 - 1.9e-05 24.6 1.2 0.2 11.8 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO14832.1 - 0.00036 20.0 3.7 0.22 11.0 0.0 3.9 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO14832.1 - 0.00057 19.5 0.7 1.8 8.4 0.0 3.9 3 0 0 3 3 3 2 Kelch motif NiFe_hyd_SSU_C PF14720.1 ETO14832.1 - 0.074 13.0 0.6 5.2 7.1 0.0 2.9 3 0 0 3 3 3 0 NiFe/NiFeSe hydrogenase small subunit C-terminal Kelch_3 PF13415.1 ETO14832.1 - 0.65 10.2 2.8 21 5.4 0.0 3.4 4 0 0 4 4 4 0 Galactose oxidase, central domain Apis_Csd PF11671.3 ETO14834.1 - 0.0022 17.8 5.1 0.0035 17.1 3.6 1.4 1 0 0 1 1 1 1 Complementary sex determiner protein DUF1168 PF06658.7 ETO14834.1 - 0.023 14.2 14.4 0.034 13.6 10.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) FLO_LFY PF01698.11 ETO14834.1 - 0.16 10.7 11.0 0.21 10.4 7.7 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein PBP1_TM PF14812.1 ETO14834.1 - 3.9 7.8 16.3 0.46 10.8 7.4 2.1 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_S8 PF00082.17 ETO14835.1 - 1.6e-05 24.2 0.0 2.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Subtilase family RPEL PF02755.10 ETO14836.1 - 1.5e-06 27.3 0.0 0.068 12.5 0.1 3.2 2 0 0 2 2 2 2 RPEL repeat DUF725 PF05267.7 ETO14836.1 - 5.6 6.8 10.2 1.5 8.7 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF725) EF-hand_6 PF13405.1 ETO14837.1 - 2.2e-05 23.9 7.4 0.099 12.5 1.2 3.7 3 0 0 3 3 3 2 EF-hand domain DUF2088 PF09861.4 ETO14837.1 - 5.2e-05 22.3 0.0 9.2e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2088) EF-hand_7 PF13499.1 ETO14837.1 - 0.00029 20.9 7.2 0.0012 18.9 2.9 3.0 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO14837.1 - 0.0011 18.0 15.8 0.013 14.7 0.1 4.4 5 0 0 5 5 5 2 EF hand EF-hand_5 PF13202.1 ETO14837.1 - 0.0078 15.5 8.7 0.19 11.1 0.1 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 ETO14837.1 - 0.011 15.2 14.3 0.086 12.4 0.7 3.6 5 0 0 5 5 5 0 EF-hand domain pair FAT PF02259.18 ETO14837.1 - 0.054 12.4 0.3 0.087 11.7 0.2 1.3 1 0 0 1 1 1 0 FAT domain ZZ PF00569.12 ETO14837.1 - 3.4 7.2 7.9 15 5.2 5.5 2.0 1 1 0 1 1 1 0 Zinc finger, ZZ type WD40 PF00400.27 ETO14838.1 - 6.5e-31 105.0 0.3 1.1e-10 41.0 0.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat eIF2A PF08662.6 ETO14838.1 - 6.7e-05 22.6 0.8 0.012 15.3 0.1 2.1 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO14838.1 - 0.00026 19.2 0.3 0.27 9.3 0.0 2.6 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Mid2 PF04478.7 ETO14838.1 - 0.0006 19.2 0.5 0.34 10.2 0.1 2.5 2 1 1 3 3 3 2 Mid2 like cell wall stress sensor PQQ_2 PF13360.1 ETO14838.1 - 0.01 15.3 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 PQQ-like domain DUF3601 PF12208.3 ETO14838.1 - 0.12 12.3 0.1 4.2 7.3 0.0 3.0 1 1 3 4 4 4 0 Domain of unknown function (DUF3601) WD40 PF00400.27 ETO14839.1 - 2.2e-59 195.3 15.4 1.9e-13 49.7 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO14839.1 - 4.2e-12 46.1 1.2 7.4e-05 22.5 0.1 3.6 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO14839.1 - 1.3e-05 24.7 4.8 20 4.9 0.0 5.8 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO14839.1 - 1.3e-05 23.5 6.1 0.084 10.9 0.0 4.2 2 2 4 6 6 6 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO14839.1 - 2.8e-05 23.0 10.8 2 7.0 0.1 5.1 1 1 3 4 4 4 4 Nup133 N terminal like Nbas_N PF15492.1 ETO14839.1 - 5.7e-05 22.3 0.7 0.44 9.5 0.0 4.6 1 1 2 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 ETO14839.1 - 8.5e-05 21.0 0.1 0.0043 15.4 0.0 2.8 1 1 2 3 3 3 1 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 ETO14839.1 - 0.00017 20.8 2.3 0.13 11.6 0.0 4.2 5 0 0 5 5 5 1 Proteasome subunit A N-terminal signature DUF866 PF05907.8 ETO14839.1 - 0.046 13.2 1.1 1.4 8.4 0.0 3.1 3 1 0 3 3 3 0 Eukaryotic protein of unknown function (DUF866) Ricin_B_lectin PF00652.17 ETO14839.1 - 0.59 10.1 5.0 9.4 6.2 0.3 3.3 3 2 0 3 3 3 0 Ricin-type beta-trefoil lectin domain TFIIIC_delta PF12657.2 ETO14839.1 - 4.1 7.0 8.0 12 5.5 1.1 3.2 2 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term WD40 PF00400.27 ETO14841.1 - 1.7e-22 78.4 2.5 6.2e-09 35.4 0.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat RRF_GI PF12614.3 ETO14841.1 - 0.042 13.6 1.0 0.073 12.8 0.7 1.3 1 0 0 1 1 1 0 Ribosome recycling factor PQQ_3 PF13570.1 ETO14841.1 - 0.15 12.3 0.2 1 9.7 0.0 2.3 3 0 0 3 3 3 0 PQQ-like domain XhlA PF10779.4 ETO14841.1 - 1.3 8.9 6.0 2.8 7.9 4.2 1.6 1 0 0 1 1 1 0 Haemolysin XhlA DUF262 PF03235.9 ETO14842.1 - 1.2 9.0 12.4 1.4 8.8 8.6 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF262 DUF3346 PF11826.3 ETO14842.1 - 2.3 7.9 6.5 2.7 7.7 4.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3346) DDHD PF02862.12 ETO14842.1 - 2.4 7.8 13.0 2.7 7.7 9.0 1.0 1 0 0 1 1 1 0 DDHD domain BSMAP PF12280.3 ETO14842.1 - 4 7.2 9.2 4.6 7.0 6.4 1.0 1 0 0 1 1 1 0 Brain specific membrane anchored protein DUF4448 PF14610.1 ETO14842.1 - 4.1 6.8 8.3 4.3 6.7 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) SpoIIP PF07454.6 ETO14842.1 - 4.6 6.3 16.0 4.8 6.2 11.1 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) SprA-related PF12118.3 ETO14842.1 - 4.7 6.4 13.5 5 6.3 9.3 1.0 1 0 0 1 1 1 0 SprA-related family Zip PF02535.17 ETO14842.1 - 5.9 5.7 6.7 6.3 5.6 4.6 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter AIF_C PF14721.1 ETO14842.1 - 6 7.1 12.7 6.5 6.9 8.8 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Pilt PF15453.1 ETO14842.1 - 6.4 6.3 9.4 6.7 6.2 6.5 1.0 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions DUF1632 PF07857.7 ETO14842.1 - 8 5.6 6.4 8.7 5.5 4.4 1.0 1 0 0 1 1 1 0 CEO family (DUF1632) Tim54 PF11711.3 ETO14842.1 - 8.1 4.9 13.9 9.1 4.7 9.6 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FixO PF02433.10 ETO14842.1 - 8.3 5.7 7.1 9.4 5.5 4.9 1.0 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO GOLD_2 PF13897.1 ETO14842.1 - 9.5 6.4 7.6 12 6.1 5.3 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking zf-C3HC4_2 PF13923.1 ETO14843.1 - 0.012 15.6 2.4 0.034 14.1 0.8 2.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 ETO14843.1 - 0.19 11.6 2.0 0.48 10.3 0.9 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-MIZ PF02891.15 ETO14843.1 - 0.33 10.5 3.8 0.16 11.4 0.7 2.0 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-C3HC4 PF00097.20 ETO14843.1 - 1.6 8.4 5.8 17 5.1 0.1 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) eIF-5_eIF-2B PF01873.12 ETO14844.1 - 1.5e-16 60.1 1.6 1.5e-16 60.1 1.1 1.8 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.13 ETO14844.1 - 1.6e-10 40.7 0.6 1.6e-10 40.7 0.4 2.6 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Stanniocalcin PF03298.8 ETO14845.1 - 0.039 12.9 1.7 0.065 12.2 1.2 1.4 1 0 0 1 1 1 0 Stanniocalcin family DUF1799 PF08809.6 ETO14845.1 - 0.077 12.8 1.1 4.2 7.2 0.0 2.4 2 0 0 2 2 2 0 Phage related hypothetical protein (DUF1799) FliT PF05400.8 ETO14845.1 - 0.37 11.2 0.1 0.37 11.2 0.1 2.4 2 1 0 2 2 2 0 Flagellar protein FliT FBP PF07299.6 ETO14845.1 - 0.73 9.1 13.6 0.48 9.7 8.0 1.7 1 1 1 2 2 2 0 Fibronectin-binding protein (FBP) Takusan PF04822.8 ETO14845.1 - 3.3 7.5 20.2 3 7.6 2.5 2.6 1 1 1 2 2 2 0 Takusan ARD PF03079.9 ETO14845.1 - 3.5 7.5 9.8 4.8 7.1 6.4 1.5 1 1 0 1 1 1 0 ARD/ARD' family ERbeta_N PF12497.3 ETO14846.1 - 0.1 12.4 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Estrogen receptor beta HAP1_N PF04849.8 ETO14847.1 - 0.0024 16.8 0.1 0.0031 16.4 0.0 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Radial_spoke PF04712.7 ETO14847.1 - 0.061 12.0 0.1 0.078 11.7 0.1 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein DUF3987 PF13148.1 ETO14847.1 - 0.95 7.9 4.5 1.3 7.5 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AlphaC_N PF08829.5 ETO14848.1 - 0.044 13.1 0.1 0.056 12.7 0.1 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal Symplekin_C PF12295.3 ETO14848.1 - 0.056 13.3 1.2 0.1 12.5 0.3 1.7 1 1 1 2 2 2 0 Symplekin tight junction protein C terminal Ank_3 PF13606.1 ETO14848.1 - 0.081 13.2 0.3 0.46 10.8 0.1 2.4 2 0 0 2 2 2 0 Ankyrin repeat Med28 PF11594.3 ETO14848.1 - 4.5 7.5 6.1 9.1 6.5 0.2 2.2 1 1 1 2 2 2 0 Mediator complex subunit 28 Lactamase_B_3 PF13483.1 ETO14849.1 - 0.099 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Kelch_6 PF13964.1 ETO14850.1 - 0.0004 20.4 1.1 0.0036 17.4 0.0 2.8 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 ETO14850.1 - 0.014 14.9 4.0 0.051 13.1 0.3 3.2 4 0 0 4 4 4 0 Kelch motif Glucokinase PF02685.11 ETO14850.1 - 0.036 12.8 0.0 1.4 7.6 0.0 2.1 2 0 0 2 2 2 0 Glucokinase GlcNAc PF11397.3 ETO14851.1 - 6.6e-35 120.8 0.0 7.6e-35 120.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) Glyco_trans_2_3 PF13632.1 ETO14851.1 - 0.0068 16.1 0.0 0.0068 16.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Kelch_5 PF13854.1 ETO14853.1 - 5.9e-05 22.9 0.3 0.0025 17.7 0.1 3.2 3 0 0 3 3 3 1 Kelch motif gp32 PF08804.5 ETO14853.1 - 0.011 15.8 0.4 6.6 6.9 0.0 2.6 1 1 1 2 2 2 0 gp32 DNA binding protein like Kelch_6 PF13964.1 ETO14853.1 - 0.011 15.8 5.4 5 7.4 0.1 4.2 4 0 0 4 4 4 0 Kelch motif Kelch_1 PF01344.20 ETO14853.1 - 0.038 13.5 0.1 0.038 13.5 0.1 3.7 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.10 ETO14853.1 - 0.71 9.7 4.7 4.6 7.1 0.2 3.7 4 0 0 4 4 4 0 Kelch motif VWA_2 PF13519.1 ETO14854.1 - 7.5e-16 58.7 0.1 1.2e-15 58.0 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 ETO14854.1 - 1.7e-08 34.3 0.1 3.3e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 ETO14854.1 - 0.005 16.5 0.1 0.014 15.1 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain tRNA_NucTransf2 PF09249.6 ETO14854.1 - 0.054 13.3 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 tRNA nucleotidyltransferase, second domain NOG1 PF06858.9 ETO14854.1 - 0.055 13.3 0.0 3 7.7 0.0 2.5 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) NUC173 PF08161.7 ETO14855.1 - 1.4e-11 44.1 0.0 6.1e-08 32.2 0.0 2.8 2 0 0 2 2 2 2 NUC173 domain DUF2373 PF10180.4 ETO14855.1 - 0.0076 15.7 0.1 0.9 9.1 0.0 2.8 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2373) Borrelia_P83 PF05262.6 ETO14856.1 - 3.5 5.7 20.9 4.5 5.4 14.5 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Gag_spuma PF03276.9 ETO14856.1 - 4.4 5.5 12.9 4.9 5.3 8.9 1.2 1 0 0 1 1 1 0 Spumavirus gag protein DUF1510 PF07423.6 ETO14856.1 - 7.4 5.8 39.3 0.23 10.7 13.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) IncA PF04156.9 ETO14857.1 - 0.011 15.3 7.5 0.013 15.1 5.2 1.0 1 0 0 1 1 1 0 IncA protein MRP-L46 PF11788.3 ETO14857.1 - 0.1 13.2 1.9 0.12 13.0 1.3 1.2 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 DUF2730 PF10805.3 ETO14857.1 - 0.17 11.6 4.2 1.6 8.5 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) BRICHOS PF04089.9 ETO14857.1 - 0.3 10.9 1.8 3.9 7.3 0.2 2.1 1 1 1 2 2 2 0 BRICHOS domain DUF421 PF04239.7 ETO14857.1 - 0.48 9.9 5.8 0.13 11.8 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF421) DUF342 PF03961.8 ETO14857.1 - 0.64 8.3 9.5 0.72 8.2 6.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2408 PF10303.4 ETO14857.1 - 0.66 10.0 6.5 1.4 9.0 4.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) IFP_35_N PF07334.8 ETO14857.1 - 0.69 9.9 12.0 4.2 7.4 0.2 2.5 2 1 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus 7tm_6 PF02949.15 ETO14857.1 - 1.1 8.0 3.9 4.2 6.1 0.4 2.0 2 0 0 2 2 2 0 7tm Odorant receptor Exonuc_VII_L PF02601.10 ETO14857.1 - 1.3 8.1 7.8 1.7 7.7 5.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit SlyX PF04102.7 ETO14857.1 - 1.4 9.3 5.6 6.6 7.1 0.2 2.3 2 0 0 2 2 2 0 SlyX DUF4404 PF14357.1 ETO14857.1 - 4 7.9 6.7 5.3 7.5 4.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) HSP70 PF00012.15 ETO14858.1 - 3.7e-13 48.2 2.4 1.3e-12 46.4 0.0 2.6 2 1 0 3 3 3 1 Hsp70 protein zf-TAZ PF02135.11 ETO14858.1 - 0.68 9.9 6.9 0.63 10.1 0.9 3.1 3 0 0 3 3 3 0 TAZ zinc finger PHD PF00628.24 ETO14859.1 - 0.0012 18.4 17.8 0.0022 17.6 12.3 1.4 1 0 0 1 1 1 1 PHD-finger YL1 PF05764.8 ETO14859.1 - 0.004 16.7 16.1 0.006 16.2 11.1 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Astro_capsid PF03115.9 ETO14859.1 - 1.1 7.4 9.4 1.6 6.9 6.5 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Exo_endo_phos PF03372.18 ETO14860.1 - 2e-16 60.6 0.0 2.8e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 ETO14860.1 - 2.2e-05 24.0 0.8 4.8e-05 22.9 0.6 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Tup_N PF08581.5 ETO14861.1 - 0.034 14.3 1.4 0.034 14.3 1.0 2.6 2 0 0 2 2 2 0 Tup N-terminal HSCB_C PF07743.8 ETO14861.1 - 0.25 11.8 3.3 12 6.4 0.2 2.9 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain HrcA PF01628.16 ETO14861.1 - 0.84 9.1 5.6 2.4 7.6 0.4 2.2 2 0 0 2 2 2 0 HrcA protein C terminal domain DUF2605 PF10792.4 ETO14861.1 - 2.8 7.6 6.4 7.1 6.3 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2605) EF-hand_1 PF00036.27 ETO14863.1 - 0.0022 17.1 0.0 0.0039 16.3 0.0 1.4 1 0 0 1 1 1 1 EF hand SPARC_Ca_bdg PF10591.4 ETO14863.1 - 0.0036 17.3 0.1 0.0048 16.9 0.1 1.3 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.1 ETO14863.1 - 0.0058 15.9 0.0 0.0092 15.2 0.0 1.3 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 ETO14863.1 - 0.01 15.9 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.1 ETO14863.1 - 0.027 14.3 0.3 0.065 13.1 0.0 1.7 2 0 0 2 2 2 0 EF-hand domain VAR1 PF05316.7 ETO14864.1 - 0.018 13.6 0.2 0.018 13.6 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein (VAR1) ADH_zinc_N PF00107.21 ETO14865.1 - 1.2e-11 44.3 0.0 2.2e-11 43.3 0.0 1.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETO14865.1 - 0.00023 22.0 0.0 0.00042 21.1 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase DUF663 PF04950.7 ETO14867.1 - 4.8e-38 130.8 0.0 4.8e-38 130.8 0.0 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF663) AARP2CN PF08142.7 ETO14867.1 - 9.2e-18 63.5 0.0 3.2e-17 61.8 0.0 2.0 1 0 0 1 1 1 1 AARP2CN (NUC121) domain DUF663 PF04950.7 ETO14868.1 - 4.8e-20 71.7 0.1 5.3e-20 71.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF663) UDPG_MGDP_dh_N PF03721.9 ETO14870.1 - 1.4e-54 184.2 0.0 2.3e-54 183.6 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 ETO14870.1 - 9.1e-34 115.8 0.5 1.5e-32 111.8 0.1 2.6 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 ETO14870.1 - 5.3e-33 113.0 0.1 2.2e-32 111.1 0.0 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_7 PF13241.1 ETO14870.1 - 0.058 13.6 0.1 1.9 8.8 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 ETO14870.1 - 0.082 12.6 0.1 0.79 9.4 0.0 2.6 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SPA PF08616.5 ETO14871.1 - 2e-06 27.4 0.0 6.7e-06 25.7 0.0 1.9 1 1 0 1 1 1 1 Stabilization of polarity axis Vfa1 PF08432.5 ETO14871.1 - 0.29 11.1 16.6 0.95 9.4 11.5 1.9 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 HSP90 PF00183.13 ETO14871.1 - 1.7 6.9 17.6 2.6 6.3 12.2 1.2 1 0 0 1 1 1 0 Hsp90 protein Afi1 PF07792.7 ETO14871.1 - 4 7.4 17.4 0.3 11.0 6.5 2.9 2 1 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Nop14 PF04147.7 ETO14871.1 - 7.8 4.2 22.7 16 3.2 15.8 1.4 1 0 0 1 1 1 0 Nop14-like family eIF-3c_N PF05470.7 ETO14871.1 - 9.5 4.1 14.7 16 3.4 10.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF2360 PF10152.4 ETO14874.1 - 5.2e-09 36.5 11.8 4.7e-07 30.1 0.3 2.6 2 1 0 2 2 2 2 Predicted coiled-coil domain-containing protein (DUF2360) ALIX_LYPXL_bnd PF13949.1 ETO14874.1 - 0.058 12.3 0.0 0.072 12.0 0.0 1.1 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Mito_fiss_reg PF05308.6 ETO14874.1 - 0.35 10.2 5.4 0.31 10.3 3.1 1.4 1 1 0 1 1 1 0 Mitochondrial fission regulator Cation_ATPase_N PF00690.21 ETO14875.1 - 8.5e-16 57.1 1.4 3.5e-13 48.7 0.5 3.0 2 1 0 2 2 2 1 Cation transporter/ATPase, N-terminus DUF2722 PF10846.3 ETO14875.1 - 0.0065 15.5 0.2 0.0079 15.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Pex14_N PF04695.8 ETO14875.1 - 0.058 13.4 0.0 0.072 13.1 0.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region E1-E2_ATPase PF00122.15 ETO14875.1 - 0.29 10.1 4.3 1.3 8.0 0.1 2.2 1 1 1 2 2 2 0 E1-E2 ATPase RNase_H2-Ydr279 PF09468.5 ETO14875.1 - 1.6 7.8 7.2 2.2 7.4 5.0 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF1049 PF06305.6 ETO14875.1 - 4.2 6.9 5.0 1.6 8.2 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1049) UCH PF00443.24 ETO14876.1 - 8.2e-20 71.0 0.0 1.3e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Suppressor_P21 PF11479.3 ETO14877.1 - 0.031 14.0 0.4 0.051 13.3 0.3 1.4 1 0 0 1 1 1 0 RNA silencing suppressor P21 FNIP_M PF14637.1 ETO14877.1 - 0.091 12.3 5.8 0.37 10.3 0.5 2.3 2 0 0 2 2 2 0 Folliculin-interacting protein middle domain DUF3452 PF11934.3 ETO14877.1 - 0.93 8.8 10.8 0.59 9.4 0.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3452) Ion_trans_2 PF07885.11 ETO14878.1 - 1.1e-15 57.0 25.7 3.3e-10 39.5 1.5 3.8 4 0 0 4 4 4 3 Ion channel DUF1275 PF06912.6 ETO14878.1 - 0.0062 15.7 1.1 0.012 14.8 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1275) Lig_chan PF00060.21 ETO14878.1 - 0.27 10.9 2.0 0.43 10.2 0.0 2.2 1 1 1 2 2 2 0 Ligand-gated ion channel Orbi_NS3 PF01616.11 ETO14879.1 - 0.19 10.6 0.6 0.54 9.1 0.4 1.7 1 0 0 1 1 1 0 Orbivirus NS3 DUF973 PF06157.6 ETO14879.1 - 2.3 7.1 16.9 0.14 11.1 4.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF973) Peptidase_S49_N PF08496.5 ETO14880.1 - 2.2 8.0 5.1 0.49 10.1 1.2 1.6 2 0 0 2 2 2 0 Peptidase family S49 N-terminal TSGP1 PF07771.6 ETO14880.1 - 7.1 6.5 10.4 0.87 9.4 3.8 1.9 1 1 0 2 2 2 0 Tick salivary peptide group 1 BACK PF07707.10 ETO14881.1 - 7.8e-08 32.0 0.2 5.5e-05 22.9 0.1 2.7 2 0 0 2 2 2 2 BTB And C-terminal Kelch DUF3513 PF12026.3 ETO14881.1 - 2 7.9 16.4 0.11 11.9 5.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3513) CAP_GLY PF01302.20 ETO14882.1 - 1.4e-33 114.4 3.0 1.5e-18 66.2 0.1 2.2 2 0 0 2 2 2 2 CAP-Gly domain MAPEG PF01124.13 ETO14883.1 - 0.39 10.3 3.5 6.6 6.3 0.1 2.1 1 1 1 2 2 2 0 MAPEG family NRDE-2 PF08424.5 ETO14884.1 - 1.4e-20 73.4 11.1 1.4e-20 73.4 7.7 2.2 2 1 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_17 PF13431.1 ETO14884.1 - 0.14 12.4 7.5 2.5 8.5 0.1 4.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETO14884.1 - 0.22 11.5 3.5 0.19 11.7 0.5 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TP53IP5 PF15331.1 ETO14887.1 - 0.014 15.3 1.0 0.014 15.3 0.7 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 GCR1_C PF12550.3 ETO14887.1 - 0.08 12.8 1.9 0.1 12.5 1.3 1.3 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes NCKAP5 PF15246.1 ETO14887.1 - 0.12 11.7 4.1 0.13 11.6 2.8 1.1 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein QueC PF06508.8 ETO14887.1 - 0.12 11.5 1.1 0.15 11.2 0.8 1.0 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Microcin PF03526.8 ETO14887.1 - 0.47 10.0 3.8 1.2 8.7 2.6 1.7 1 1 0 1 1 1 0 Colicin E1 (microcin) immunity protein DUF4304 PF14137.1 ETO14887.1 - 0.67 10.0 5.9 0.81 9.8 3.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4304) Myc-LZ PF02344.10 ETO14887.1 - 1.2 8.8 4.5 2.8 7.6 2.4 2.0 2 0 0 2 2 2 0 Myc leucine zipper domain PWWP PF00855.12 ETO14887.1 - 8 6.7 7.0 24 5.2 3.8 1.9 1 1 1 2 2 2 0 PWWP domain NACHT PF05729.7 ETO14888.1 - 9.3e-11 41.6 0.0 2.4e-10 40.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO14888.1 - 2.4e-05 24.6 0.2 0.00017 21.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETO14888.1 - 0.00011 22.4 0.0 0.00049 20.2 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO14888.1 - 0.001 19.9 0.1 0.0084 16.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 ETO14888.1 - 0.011 15.9 0.8 0.053 13.8 0.5 2.2 1 1 0 1 1 1 0 ABC transporter UPF0079 PF02367.12 ETO14888.1 - 0.025 14.2 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 ETO14888.1 - 0.083 13.0 4.8 0.22 11.7 0.0 3.5 3 1 0 3 3 3 0 RNA helicase CUE PF02845.11 ETO14888.1 - 0.089 12.3 0.1 0.33 10.4 0.0 2.0 2 0 0 2 2 2 0 CUE domain GPS PF01825.16 ETO14890.1 - 2.9e-09 36.8 9.0 9.8e-09 35.1 6.2 2.0 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain WD40 PF00400.27 ETO14891.1 - 5.5e-69 225.7 20.0 5.7e-11 41.8 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO14891.1 - 3.8e-12 45.1 7.1 0.059 11.4 0.1 6.4 3 1 3 7 7 7 6 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO14891.1 - 0.00049 20.4 0.5 0.00049 20.4 0.4 2.6 2 0 0 2 2 2 1 TRAF-type zinc finger Kelch_6 PF13964.1 ETO14891.1 - 0.0017 18.4 6.3 5.8 7.2 0.0 5.5 5 1 0 5 5 5 1 Kelch motif Atg14 PF10186.4 ETO14891.1 - 0.011 14.6 14.9 0.019 13.9 10.3 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Metallothi_Euk2 PF12809.2 ETO14891.1 - 0.45 10.9 4.3 0.87 10.0 1.1 2.6 2 0 0 2 2 2 0 Eukaryotic metallothionein Metallophos_2 PF12850.2 ETO14892.1 - 2.7e-06 27.3 0.0 4.1e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 ETO14892.1 - 0.00037 19.9 2.4 0.0031 16.9 1.7 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Kinesin PF00225.18 ETO14893.1 - 4.6e-19 68.2 0.0 4.6e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain YMF19 PF02326.10 ETO14893.1 - 3.3 8.3 8.9 7.4 7.2 2.5 2.4 2 0 0 2 2 2 0 Plant ATP synthase F0 DUF2304 PF10066.4 ETO14895.1 - 0.079 12.8 1.5 0.14 12.0 1.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) Peptidase_M50B PF13398.1 ETO14895.1 - 0.15 11.4 1.1 0.18 11.1 0.8 1.2 1 0 0 1 1 1 0 Peptidase M50B-like DUF740 PF05340.7 ETO14895.1 - 0.47 8.7 4.8 0.57 8.4 3.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Protocadherin PF08374.6 ETO14895.1 - 4.2 6.9 10.0 7.1 6.1 6.9 1.3 1 0 0 1 1 1 0 Protocadherin PerC PF06069.6 ETO14897.1 - 0.11 12.6 0.1 0.32 11.0 0.0 1.8 2 0 0 2 2 2 0 PerC transcriptional activator Ribosomal_L39 PF00832.15 ETO14897.1 - 0.23 10.9 1.4 0.36 10.3 0.1 2.0 2 0 0 2 2 2 0 Ribosomal L39 protein Gly_rich PF12810.2 ETO14898.1 - 1.5e-07 31.2 24.7 8e-07 28.8 17.1 2.0 1 1 0 1 1 1 1 Glycine rich protein DUF3764 PF12594.3 ETO14899.1 - 0.029 14.0 1.4 0.39 10.4 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3764) CDC37_N PF03234.9 ETO14899.1 - 0.1 12.9 16.4 1.7 8.9 8.0 2.1 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding DUF1664 PF07889.7 ETO14899.1 - 1.1 9.1 6.5 0.84 9.4 3.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) CAP_GLY PF01302.20 ETO14900.1 - 2.8e-24 84.5 6.5 2.3e-07 30.4 0.0 4.4 4 0 0 4 4 4 4 CAP-Gly domain WWE PF02825.15 ETO14901.1 - 0.011 15.1 1.5 0.066 12.6 0.5 2.3 2 1 0 2 2 2 0 WWE domain DUF2229 PF09989.4 ETO14901.1 - 0.019 14.4 4.4 0.021 14.3 3.1 1.2 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) UPF0231 PF06062.6 ETO14901.1 - 0.088 12.6 2.6 0.092 12.6 0.9 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0231) Arena_glycoprot PF00798.13 ETO14901.1 - 0.093 11.1 9.9 0.1 10.9 6.8 1.0 1 0 0 1 1 1 0 Arenavirus glycoprotein Neuropeptide_S PF14993.1 ETO14902.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Neuropeptide S precursor protein Pcc1 PF09341.5 ETO14903.1 - 4.3e-07 29.8 0.0 8.2e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Transcription factor Pcc1 Chisel PF15355.1 ETO14903.1 - 0.17 11.9 1.4 6.8 6.7 1.1 2.2 2 0 0 2 2 2 0 Stretch-responsive small skeletal muscle X protein, Chisel DUF2207 PF09972.4 ETO14904.1 - 0.056 12.0 0.5 0.065 11.8 0.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Tubulin PF00091.20 ETO14905.1 - 1.8e-07 31.2 0.1 2.1e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain RnaseA PF00074.15 ETO14907.1 - 0.049 13.9 1.1 0.09 13.0 0.8 1.4 1 0 0 1 1 1 0 Pancreatic ribonuclease SecA_DEAD PF07517.9 ETO14908.1 - 9.8e-11 41.4 0.0 5.3e-10 39.0 0.0 2.3 1 1 0 1 1 1 1 SecA DEAD-like domain DUF3783 PF12646.2 ETO14908.1 - 0.083 12.6 0.2 0.44 10.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) Pkinase PF00069.20 ETO14909.1 - 0.00032 19.9 0.0 0.00042 19.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain NST1 PF13945.1 ETO14910.1 - 1.2 9.1 5.6 1 9.3 3.3 1.3 1 1 0 1 1 1 0 Salt tolerance down-regulator Gemini_AL2 PF01440.11 ETO14910.1 - 2 8.5 4.7 0.64 10.1 0.9 1.7 1 1 1 2 2 2 0 Geminivirus AL2 protein RVT_1 PF00078.22 ETO14912.1 - 2.6e-12 46.5 1.2 1e-11 44.6 0.1 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Kelch_1 PF01344.20 ETO14913.1 - 1.5e-05 24.4 0.8 0.00038 19.9 0.4 2.6 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETO14913.1 - 0.00031 20.7 0.3 0.003 17.6 0.1 2.3 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.10 ETO14913.1 - 0.19 11.5 1.1 1.1 9.1 0.0 2.7 3 1 0 3 3 3 0 Kelch motif DUF3300 PF11737.3 ETO14914.1 - 0.085 12.1 0.2 0.09 12.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3300) WD40 PF00400.27 ETO14915.1 - 0.42 10.5 4.5 37 4.4 0.0 3.5 3 0 0 3 3 3 0 WD domain, G-beta repeat Mcp5_PH PF12814.2 ETO14916.1 - 2.7e-06 27.2 0.0 9.3e-06 25.5 0.0 1.9 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology DUF3899 PF13038.1 ETO14916.1 - 4.8 7.4 5.7 1.2 9.2 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) GN3L_Grn1 PF08701.6 ETO14918.1 - 7.9e-11 41.7 23.2 7.9e-11 41.7 16.1 1.8 1 1 0 1 1 1 1 GNL3L/Grn1 putative GTPase DUF3781 PF12636.2 ETO14918.1 - 0.011 15.7 1.6 0.67 9.9 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3781) XPG_I_2 PF12813.2 ETO14918.1 - 0.14 11.6 1.0 0.17 11.3 0.7 1.2 1 0 0 1 1 1 0 XPG domain containing Selenoprotein_S PF06936.6 ETO14918.1 - 0.14 11.6 4.6 0.2 11.1 3.2 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) GAGA_bind PF06217.7 ETO14918.1 - 0.16 11.9 8.6 0.19 11.6 5.9 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family TORC_M PF12885.2 ETO14918.1 - 0.85 9.3 3.2 1.2 8.8 2.1 1.4 1 1 0 1 1 1 0 Transducer of regulated CREB activity middle domain Ctr PF04145.10 ETO14918.1 - 2.2 8.2 7.6 17 5.4 5.2 1.9 1 1 0 1 1 1 0 Ctr copper transporter family ATP-synt_E PF05680.7 ETO14918.1 - 4.2 7.3 14.1 3.8 7.5 3.8 2.1 2 0 0 2 2 2 0 ATP synthase E chain WD40 PF00400.27 ETO14919.1 - 1.6e-40 135.5 6.1 7.4e-11 41.4 0.3 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO14919.1 - 8.5e-05 21.4 0.5 0.67 8.6 0.0 3.0 1 1 1 3 3 3 2 Nup133 N terminal like eIF2A PF08662.6 ETO14919.1 - 0.0082 15.8 0.0 0.29 10.8 0.0 2.6 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO14919.1 - 0.0098 14.0 1.4 2.3 6.2 0.1 3.0 1 1 2 3 3 3 2 Nucleoporin Nup120/160 PD40 PF07676.7 ETO14919.1 - 0.087 12.5 2.3 89 2.9 0.0 4.7 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF4072 PF13284.1 ETO14919.1 - 0.11 12.6 0.0 6.1 7.1 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4072) Kelch_4 PF13418.1 ETO14920.1 - 0.00011 21.8 0.1 0.00022 20.9 0.0 1.5 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO14920.1 - 0.0038 16.7 0.6 0.0075 15.7 0.4 1.5 1 0 0 1 1 1 1 Kelch motif NACHT PF05729.7 ETO14921.1 - 8.2e-08 32.0 0.1 1.8e-07 30.9 0.0 1.5 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 ETO14921.1 - 0.00089 18.9 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 ETO14921.1 - 0.0017 18.3 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain KaiC PF06745.8 ETO14921.1 - 0.0017 17.5 0.0 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 KaiC NB-ARC PF00931.17 ETO14921.1 - 0.0021 16.9 0.2 0.017 13.9 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain DUF2075 PF09848.4 ETO14921.1 - 0.0049 15.8 0.1 0.024 13.6 0.0 1.9 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DAP3 PF10236.4 ETO14921.1 - 0.0082 15.1 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.1 ETO14921.1 - 0.026 14.6 0.0 0.095 12.8 0.0 1.9 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 ETO14921.1 - 0.041 14.0 0.2 0.36 11.0 0.0 2.5 2 1 1 3 3 3 0 RNA helicase AAA_25 PF13481.1 ETO14921.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 ETO14921.1 - 0.15 11.5 1.6 0.21 11.1 0.0 2.0 3 1 0 3 3 3 0 AAA domain HEAT_2 PF13646.1 ETO14922.1 - 2.3e-17 63.0 0.0 0.0009 19.4 0.0 7.9 3 2 6 9 9 9 7 HEAT repeats HEAT PF02985.17 ETO14922.1 - 1.7e-15 55.6 2.0 0.73 10.0 0.0 12.1 12 0 0 12 12 12 3 HEAT repeat NACHT PF05729.7 ETO14922.1 - 4e-07 29.8 0.1 1.9e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 NACHT domain HEAT_EZ PF13513.1 ETO14922.1 - 2.9e-06 27.5 1.4 0.86 10.1 0.0 6.2 4 2 5 9 9 7 1 HEAT-like repeat Ank_2 PF12796.2 ETO14922.1 - 0.00017 21.8 0.2 0.00098 19.4 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO14922.1 - 0.00022 21.1 0.6 0.0034 17.4 0.0 3.1 3 0 0 3 3 2 1 Ankyrin repeat Ank_5 PF13857.1 ETO14922.1 - 0.00028 21.0 0.2 0.0012 19.0 0.1 2.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO14922.1 - 0.0012 19.3 0.8 0.0083 16.6 0.2 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 ETO14922.1 - 0.015 15.1 0.0 0.058 13.2 0.0 2.2 1 0 0 1 1 1 0 Ankyrin repeat Stork_head PF10264.4 ETO14922.1 - 0.019 15.1 0.0 0.12 12.5 0.0 2.4 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain TraC PF07820.7 ETO14922.1 - 0.024 14.8 0.2 39 4.5 0.0 3.7 2 1 1 3 3 3 0 TraC-like protein WD40 PF00400.27 ETO14923.1 - 2.3e-51 169.9 16.3 4.2e-10 39.1 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat PD40 PF07676.7 ETO14923.1 - 1.4e-06 27.8 0.1 6.5 6.5 0.0 5.2 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO14923.1 - 5.5e-06 24.8 1.4 1.5 6.8 0.0 4.1 3 1 0 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO14923.1 - 6.9e-05 21.3 0.1 0.21 9.8 0.0 2.3 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO14923.1 - 0.00043 19.4 1.6 0.2 10.7 0.0 4.1 1 1 5 6 6 6 1 Neuroblastoma-amplified sequence, N terminal DPPIV_N PF00930.16 ETO14923.1 - 0.025 13.1 0.0 0.85 8.1 0.0 2.8 1 1 2 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF1513 PF07433.6 ETO14923.1 - 0.17 10.7 0.1 23 3.7 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) Proteasome_A_N PF10584.4 ETO14923.1 - 0.3 10.4 3.5 25 4.2 0.0 4.0 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Kelch_6 PF13964.1 ETO14924.1 - 1.5e-09 37.5 3.0 1.5e-05 24.9 0.2 4.3 4 1 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO14924.1 - 6e-08 32.1 0.3 6e-05 22.6 0.0 3.8 3 1 0 3 3 3 1 Kelch motif Kelch_1 PF01344.20 ETO14924.1 - 5.2e-06 25.9 1.1 0.00056 19.3 0.2 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETO14924.1 - 7.3e-06 25.6 0.3 0.0009 18.9 0.1 2.8 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO14924.1 - 0.00067 19.5 1.2 0.025 14.5 0.5 2.9 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO14924.1 - 0.0013 18.8 0.0 0.026 14.6 0.0 3.1 4 0 0 4 4 4 1 Galactose oxidase, central domain DivIC PF04977.10 ETO14925.1 - 0.02 14.3 9.3 0.02 14.3 6.4 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF3251 PF11622.3 ETO14925.1 - 0.055 12.8 1.9 0.077 12.3 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) CP12 PF02672.10 ETO14925.1 - 0.056 13.8 4.5 0.079 13.4 2.8 1.6 1 1 0 1 1 1 0 CP12 domain CHD5 PF04420.9 ETO14925.1 - 0.064 12.9 10.1 0.09 12.4 7.0 1.3 1 0 0 1 1 1 0 CHD5-like protein DUF4140 PF13600.1 ETO14925.1 - 0.54 10.7 4.4 0.63 10.5 2.5 1.6 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF342 PF03961.8 ETO14925.1 - 0.54 8.5 12.8 0.64 8.3 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AAA_11 PF13086.1 ETO14925.1 - 0.55 9.7 8.8 0.8 9.2 6.1 1.3 1 0 0 1 1 1 0 AAA domain DUF3450 PF11932.3 ETO14925.1 - 0.96 8.6 9.6 1.2 8.2 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ATG16 PF08614.6 ETO14925.1 - 1.2 8.9 19.2 0.45 10.3 9.3 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF3573 PF12097.3 ETO14925.1 - 1.2 7.7 5.8 1.4 7.4 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF3373 PF11853.3 ETO14925.1 - 1.4 7.3 5.9 1.4 7.4 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) LMBR1 PF04791.11 ETO14925.1 - 2.1 6.8 4.6 2.4 6.6 3.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TMPIT PF07851.8 ETO14925.1 - 4.5 6.2 10.7 5.3 6.0 7.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein WD40 PF00400.27 ETO14927.1 - 2.6e-33 112.7 9.6 8.4e-13 47.6 0.0 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO14927.1 - 3.1e-07 28.9 0.4 0.0032 15.6 0.1 2.3 1 1 0 2 2 2 2 Nucleoporin Nup120/160 zf-MYND PF01753.13 ETO14928.1 - 4.1e-09 36.1 13.3 9.5e-09 34.9 9.3 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 ETO14928.1 - 0.22 11.3 7.2 0.72 9.7 5.0 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DWNN PF08783.6 ETO14928.1 - 0.23 11.4 5.5 0.23 11.4 0.7 2.9 3 0 0 3 3 3 0 DWNN domain MMR_HSR1 PF01926.18 ETO14929.1 - 9.5e-06 25.5 0.0 2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.13 ETO14929.1 - 8.1e-05 21.7 0.0 0.00017 20.6 0.0 1.6 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.22 ETO14929.1 - 0.00031 20.2 0.0 0.00071 19.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_23 PF13476.1 ETO14929.1 - 0.00082 19.7 1.3 0.0016 18.7 0.9 1.5 1 1 0 1 1 1 1 AAA domain AIG1 PF04548.11 ETO14929.1 - 0.0018 17.4 0.3 0.017 14.2 0.0 2.3 3 0 0 3 3 3 1 AIG1 family DUF258 PF03193.11 ETO14929.1 - 0.004 16.3 1.7 0.026 13.7 0.1 2.8 2 1 0 2 2 2 1 Protein of unknown function, DUF258 Gtr1_RagA PF04670.7 ETO14929.1 - 0.0058 15.7 0.1 0.64 9.1 0.0 2.7 3 0 0 3 3 3 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.22 ETO14929.1 - 0.0087 16.3 0.0 0.056 13.7 0.0 2.1 2 0 0 2 2 2 1 ABC transporter PduV-EutP PF10662.4 ETO14929.1 - 0.017 14.6 0.1 0.071 12.5 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 ETO14929.1 - 0.018 14.5 0.0 0.04 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 ETO14929.1 - 0.024 14.7 0.2 0.069 13.2 0.2 2.1 1 1 0 1 1 1 0 AAA domain Drf_FH3 PF06367.11 ETO14929.1 - 0.027 13.8 0.2 0.054 12.8 0.1 1.4 1 0 0 1 1 1 0 Diaphanous FH3 Domain AAA_16 PF13191.1 ETO14929.1 - 0.028 14.4 0.0 0.065 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.1 ETO14929.1 - 0.054 13.4 0.1 0.14 12.0 0.0 1.8 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 ETO14929.1 - 0.094 11.8 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.9 ETO14929.1 - 0.094 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) HR1 PF02185.11 ETO14929.1 - 0.14 11.9 0.3 0.14 11.9 0.2 2.5 2 1 0 2 2 2 0 Hr1 repeat P-mevalo_kinase PF04275.9 ETO14929.1 - 0.39 10.4 5.0 0.51 10.0 0.8 2.2 1 1 1 2 2 2 0 Phosphomevalonate kinase WD40 PF00400.27 ETO14930.1 - 4.3e-20 70.7 0.6 3.7e-12 45.6 0.1 2.5 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO14930.1 - 0.0043 15.2 0.2 0.65 8.0 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 RabGAP-TBC PF00566.13 ETO14931.1 - 1.6e-10 40.8 0.6 1.6e-10 40.8 0.4 3.8 4 1 0 4 4 4 1 Rab-GTPase-TBC domain YL1 PF05764.8 ETO14931.1 - 0.0025 17.4 32.5 0.0025 17.4 22.5 4.6 5 1 1 6 6 6 1 YL1 nuclear protein DUF3439 PF11921.3 ETO14931.1 - 5.3 6.8 26.7 0.31 10.7 11.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) RabGAP-TBC PF00566.13 ETO14932.1 - 1.2e-14 54.3 3.1 1.2e-14 54.3 2.1 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain PH PF00169.24 ETO14932.1 - 0.043 14.0 0.1 0.091 12.9 0.1 1.6 1 0 0 1 1 1 0 PH domain ETRAMP PF09716.5 ETO14933.1 - 0.06 13.2 3.1 2.6 8.0 0.0 2.4 1 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF3343 PF11823.3 ETO14933.1 - 0.13 11.5 1.4 0.29 10.4 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3343) vATP-synt_E PF01991.13 ETO14933.1 - 1.2 8.3 11.6 1.8 7.7 8.0 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Fis1_TPR_C PF14853.1 ETO14935.1 - 0.0011 18.7 0.4 0.0031 17.3 0.3 1.7 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.1 ETO14935.1 - 0.0045 16.8 1.8 0.012 15.5 0.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO14935.1 - 0.0069 16.2 4.5 0.019 14.8 0.2 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO14935.1 - 0.007 15.9 1.0 0.007 15.9 0.7 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO14935.1 - 0.021 14.5 1.3 0.021 14.5 0.9 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO14935.1 - 0.039 14.4 0.2 0.13 12.7 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Apc3 PF12895.2 ETO14935.1 - 0.043 13.9 4.9 0.048 13.7 0.1 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 ETO14935.1 - 0.075 12.6 4.6 0.085 12.5 0.1 2.9 3 0 0 3 3 3 0 TPR repeat LMBR1 PF04791.11 ETO14936.1 - 0.27 9.7 9.8 0.22 10.0 1.0 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein UCH PF00443.24 ETO14937.1 - 1.9e-19 69.8 1.9 3.2e-19 69.1 0.2 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase NTP_transf_2 PF01909.18 ETO14938.1 - 2.2e-05 24.6 0.0 6.8e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyltransferase domain Nuc-transf PF10127.4 ETO14938.1 - 0.044 13.1 0.0 0.085 12.1 0.0 1.4 1 0 0 1 1 1 0 Predicted nucleotidyltransferase DUF294 PF03445.8 ETO14938.1 - 0.089 12.4 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative nucleotidyltransferase DUF294 Bunya_nucleocap PF00952.12 ETO14939.1 - 0.023 14.7 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Bunyavirus nucleocapsid (N) protein NACHT PF05729.7 ETO14940.1 - 1.2e-07 31.5 0.0 2.2e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DRY_EERY PF09750.4 ETO14940.1 - 1.8e-05 24.8 1.6 2.5e-05 24.3 1.1 1.1 1 0 0 1 1 1 1 Alternative splicing regulator NB-ARC PF00931.17 ETO14940.1 - 0.00097 18.0 0.5 0.012 14.4 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain DUF2075 PF09848.4 ETO14940.1 - 0.0036 16.3 0.3 0.098 11.6 0.0 2.4 2 1 1 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 ETO14940.1 - 0.0038 17.2 0.0 0.0072 16.3 0.0 1.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 ETO14940.1 - 0.0048 16.6 0.0 0.0094 15.6 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain DAP3 PF10236.4 ETO14940.1 - 0.0066 15.4 0.1 0.047 12.6 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.1 ETO14940.1 - 0.032 14.3 0.0 0.12 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 ETO14940.1 - 0.15 11.4 0.0 1.1 8.6 0.0 2.0 1 1 1 2 2 2 0 FtsK/SpoIIIE family CHD5 PF04420.9 ETO14941.1 - 0.079 12.6 0.0 0.079 12.6 0.0 2.1 2 0 0 2 2 2 0 CHD5-like protein RasGEF_N PF00618.15 ETO14941.1 - 0.11 12.5 0.2 0.11 12.5 0.1 3.9 3 1 0 3 3 3 0 RasGEF N-terminal motif CDC45 PF02724.9 ETO14942.1 - 0.0078 14.3 11.3 0.009 14.0 7.8 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF2146 PF10220.4 ETO14942.1 - 0.31 8.9 9.2 0.37 8.7 6.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) NPR3 PF03666.8 ETO14942.1 - 2 6.8 15.4 2.8 6.3 10.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Dsh_C PF12316.3 ETO14942.1 - 2.2 8.3 5.9 2.8 8.0 4.1 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal BMF PF15185.1 ETO14942.1 - 5.6 6.2 10.8 8.7 5.5 7.5 1.4 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis IncA PF04156.9 ETO14943.1 - 0.39 10.2 27.5 0.38 10.3 3.4 2.6 1 1 1 2 2 2 0 IncA protein Tropomyosin_1 PF12718.2 ETO14943.1 - 1.6 8.6 41.3 0.82 9.5 16.0 3.3 2 1 1 3 3 3 0 Tropomyosin like Cep57_CLD_2 PF14197.1 ETO14943.1 - 1.9 8.4 25.5 0.88 9.5 7.3 4.1 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 EMP24_GP25L PF01105.19 ETO14943.1 - 3.8 7.1 12.5 1.3 8.7 1.4 2.6 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD OAD_gamma PF04277.8 ETO14944.1 - 2.7 8.4 7.8 19 5.6 0.1 3.8 4 0 0 4 4 4 0 Oxaloacetate decarboxylase, gamma chain Peptidase_C12 PF01088.16 ETO14945.1 - 9.4e-42 142.6 0.0 1.5e-41 141.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 RPAP1_N PF08621.5 ETO14946.1 - 0.11 12.1 5.7 0.44 10.1 0.5 3.8 4 0 0 4 4 4 0 RPAP1-like, N-terminal RRM_1 PF00076.17 ETO14947.1 - 2.7e-12 46.1 0.0 7.3e-12 44.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO14947.1 - 4.7e-08 32.9 0.0 1.2e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO14947.1 - 6e-07 29.2 0.0 1.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 ETO14947.1 - 3e-06 26.7 0.0 6.6e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RNA_bind PF08675.6 ETO14947.1 - 0.018 15.0 0.0 0.061 13.3 0.0 1.9 1 0 0 1 1 1 0 RNA binding domain TMEM51 PF15345.1 ETO14948.1 - 0.0016 18.1 0.3 0.0016 18.1 0.2 3.2 2 1 1 3 3 3 1 Transmembrane protein 51 DUF948 PF06103.6 ETO14948.1 - 0.0058 16.4 1.6 0.0097 15.7 0.1 2.1 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF948) TMEM154 PF15102.1 ETO14948.1 - 0.018 14.7 0.2 0.018 14.7 0.2 3.4 3 1 1 4 4 4 0 TMEM154 protein family DUF1180 PF06679.7 ETO14948.1 - 0.023 14.5 0.9 0.023 14.5 0.6 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) CbtA PF09490.5 ETO14948.1 - 0.067 12.4 5.4 0.15 11.3 0.1 3.2 4 0 0 4 4 4 0 Probable cobalt transporter subunit (CbtA) Syndecan PF01034.15 ETO14948.1 - 0.099 12.3 0.8 1.5 8.5 0.0 2.5 2 0 0 2 2 2 0 Syndecan domain OAD_gamma PF04277.8 ETO14948.1 - 1.8 8.9 10.4 5.8 7.3 0.6 3.8 2 1 1 3 3 3 0 Oxaloacetate decarboxylase, gamma chain TTL PF03133.10 ETO14951.1 - 1.9e-82 276.4 4.0 1.9e-82 276.4 2.8 1.7 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 ETO14951.1 - 1.8e-06 26.9 0.4 0.0012 17.6 0.0 2.8 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 ETO14951.1 - 0.012 15.3 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain RasGEF PF00617.14 ETO14953.1 - 4.1e-34 117.9 3.3 6.1e-34 117.3 2.3 1.2 1 0 0 1 1 1 1 RasGEF domain SPX PF03105.14 ETO14953.1 - 0.0086 15.8 0.0 0.027 14.2 0.0 1.8 2 1 0 2 2 2 1 SPX domain PUF PF00806.14 ETO14954.1 - 0.0007 18.9 0.0 0.033 13.6 0.0 2.7 2 0 0 2 2 2 1 Pumilio-family RNA binding repeat DUF2746 PF10874.3 ETO14954.1 - 0.031 14.4 0.2 0.059 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) YqzE PF14038.1 ETO14954.1 - 0.047 13.4 0.4 0.089 12.5 0.3 1.4 1 0 0 1 1 1 0 YqzE-like protein EST1_DNA_bind PF10373.4 ETO14955.1 - 0.0038 16.4 0.4 0.0044 16.2 0.3 1.1 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain DRY_EERY PF09750.4 ETO14955.1 - 0.064 13.3 1.2 0.1 12.6 0.8 1.3 1 0 0 1 1 1 0 Alternative splicing regulator DUF912 PF06024.7 ETO14955.1 - 4.8 7.2 6.4 57 3.8 4.4 2.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Secretin_N_2 PF07655.8 ETO14956.1 - 3.4 8.1 17.4 7.2 7.0 8.9 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain Kelch_6 PF13964.1 ETO14957.1 - 3.5e-08 33.2 0.3 0.0012 18.9 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 ETO14957.1 - 1.7e-06 27.5 4.1 6.7e-05 22.4 0.0 3.9 4 1 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 ETO14957.1 - 3.4e-05 23.2 5.0 0.056 12.9 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETO14957.1 - 0.0016 18.1 2.8 0.03 14.0 0.0 3.7 4 1 0 4 4 4 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO14957.1 - 0.0074 16.4 0.1 0.093 12.9 0.0 2.7 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO14957.1 - 0.049 13.6 2.1 11 6.0 0.1 3.5 3 0 0 3 3 3 0 Kelch motif DUF4363 PF14276.1 ETO14958.1 - 0.029 14.0 0.2 0.064 12.9 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4363) Prefoldin_2 PF01920.15 ETO14958.1 - 0.14 11.8 0.8 0.22 11.3 0.6 1.3 1 0 0 1 1 1 0 Prefoldin subunit Peptidase_S49_N PF08496.5 ETO14959.1 - 0.068 12.9 3.6 0.098 12.4 2.5 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal BLVR PF06375.6 ETO14959.1 - 7.6 6.3 12.8 11 5.8 8.9 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) RPN7 PF10602.4 ETO14960.1 - 2.4e-13 49.8 0.0 4.9e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 ETO14960.1 - 3.8e-09 36.8 0.0 1e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.12 ETO14960.1 - 0.00048 19.8 0.1 0.0085 15.9 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO14960.1 - 0.0025 17.3 0.0 0.014 14.9 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO14960.1 - 0.02 14.6 0.0 0.17 11.7 0.0 2.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 ETO14960.1 - 0.03 13.9 0.0 0.094 12.3 0.1 1.9 2 0 0 2 2 2 0 TPR repeat TPR_4 PF07721.9 ETO14960.1 - 0.061 13.7 0.5 0.17 12.3 0.4 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETO14960.1 - 0.09 12.6 0.1 0.26 11.1 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat AHS1 PF02682.11 ETO14962.1 - 0.18 11.2 1.1 0.32 10.4 0.8 1.6 1 0 0 1 1 1 0 Allophanate hydrolase subunit 1 Med4 PF10018.4 ETO14962.1 - 0.45 9.8 22.4 0.033 13.6 11.2 2.1 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Reo_sigmaC PF04582.7 ETO14962.1 - 0.99 8.5 4.0 0.48 9.5 1.1 1.7 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Tet_JBP PF12851.2 ETO14962.1 - 5 6.3 9.6 0.094 11.9 1.0 2.3 2 1 0 2 2 2 0 Oxygenase domain of the 2OGFeDO superfamily U-box PF04564.10 ETO14963.1 - 3e-12 46.3 0.7 9.2e-12 44.7 0.1 2.3 2 0 0 2 2 2 1 U-box domain Phasin_2 PF09361.5 ETO14963.1 - 0.086 12.8 0.6 0.61 10.1 0.1 2.2 2 0 0 2 2 2 0 Phasin protein CGGC PF08821.6 ETO14963.1 - 0.72 9.9 4.4 0.28 11.2 0.3 2.2 2 0 0 2 2 2 0 CGGC domain DUF3231 PF11553.3 ETO14964.1 - 0.005 16.3 0.5 0.012 15.1 0.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF3231) Kelch_6 PF13964.1 ETO14968.1 - 0.00059 19.9 0.3 0.2 11.8 0.1 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 ETO14968.1 - 0.0092 15.9 0.1 0.55 10.2 0.0 3.2 3 0 0 3 3 3 1 Kelch motif N_Asn_amidohyd PF14736.1 ETO14968.1 - 0.012 14.4 0.1 1.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Protein N-terminal asparagine amidohydrolase Kelch_4 PF13418.1 ETO14968.1 - 0.045 13.5 0.0 0.14 11.9 0.0 1.9 1 0 0 1 1 1 0 Galactose oxidase, central domain RRM_6 PF14259.1 ETO14969.1 - 0.00037 20.4 0.0 0.00074 19.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO14969.1 - 0.00041 20.1 0.0 0.00066 19.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 ETO14969.1 - 0.00046 18.8 26.5 0.00055 18.5 18.4 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 RRM_1 PF00076.17 ETO14969.1 - 0.0064 16.1 0.0 0.019 14.5 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hex_IIIa PF02455.11 ETO14969.1 - 0.82 8.2 15.3 1 7.9 10.6 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Thioredoxin PF00085.15 ETO14970.1 - 6e-25 86.9 0.1 1e-24 86.1 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.1 ETO14970.1 - 5.1e-09 36.1 0.2 1.2e-08 34.9 0.1 1.6 2 0 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.16 ETO14970.1 - 1.4e-06 28.0 0.1 1.7e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 ETO14970.1 - 3.9e-06 26.7 0.0 9.2e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 ETO14970.1 - 3.9e-06 27.0 0.1 1.8e-05 24.8 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 ETO14970.1 - 6.3e-05 22.7 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain ERp29_N PF07912.8 ETO14970.1 - 0.00069 19.5 0.1 0.0011 18.8 0.1 1.3 1 0 0 1 1 1 1 ERp29, N-terminal domain Thioredoxin_8 PF13905.1 ETO14970.1 - 0.0014 18.7 0.2 0.0086 16.1 0.1 2.2 2 1 0 2 2 2 1 Thioredoxin-like Redoxin PF08534.5 ETO14970.1 - 0.0014 18.1 0.1 0.0032 17.0 0.0 1.5 1 1 1 2 2 2 1 Redoxin FTA4 PF13093.1 ETO14970.1 - 0.076 12.4 0.0 0.097 12.0 0.0 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Thioredoxin PF00085.15 ETO14971.1 - 7e-23 80.2 0.1 1.5e-21 76.0 0.0 2.4 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.1 ETO14971.1 - 4.2e-22 78.8 2.0 1.5e-18 67.2 0.1 3.3 1 1 2 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 ETO14971.1 - 3.7e-07 30.3 0.6 0.00027 21.0 0.1 3.4 2 2 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 ETO14971.1 - 6.2e-05 22.9 0.4 0.00073 19.5 0.0 2.7 2 1 0 2 2 2 1 Thioredoxin-like Thioredoxin_8 PF13905.1 ETO14971.1 - 0.00043 20.3 2.2 0.061 13.4 0.1 3.2 2 2 1 3 3 3 2 Thioredoxin-like WD40 PF00400.27 ETO14972.1 - 1.1e-56 186.7 9.2 2.7e-09 36.5 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO14972.1 - 2.4e-06 25.9 5.3 0.01 14.0 0.7 3.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 HARP PF07443.8 ETO14972.1 - 0.094 12.1 2.4 0.35 10.2 0.0 3.0 3 0 0 3 3 3 0 HepA-related protein (HARP) zf-TRAF PF02176.13 ETO14973.1 - 2.6e-06 27.7 2.9 2.6e-06 27.7 2.0 3.7 2 1 3 5 5 5 1 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 ETO14973.1 - 0.00034 20.5 3.5 0.0067 16.4 2.4 2.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO14973.1 - 0.0041 16.9 1.6 0.0041 16.9 1.1 2.7 2 1 0 2 2 2 1 Ring finger domain DUF2746 PF10874.3 ETO14973.1 - 0.33 11.1 2.9 8.9 6.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) DivIC PF04977.10 ETO14973.1 - 8.9 5.8 14.0 3.6 7.1 1.3 2.5 1 1 1 2 2 2 0 Septum formation initiator Tantalus PF15386.1 ETO14974.1 - 0.039 13.7 0.1 0.17 11.7 0.0 2.1 1 1 0 1 1 1 0 Drosophila Tantalus-like CAP_GLY PF01302.20 ETO14976.1 - 2.2e-09 36.8 0.0 5e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 CAP-Gly domain MTBP_mid PF14919.1 ETO14978.1 - 0.022 13.4 2.9 0.03 13.0 2.0 1.1 1 0 0 1 1 1 0 MDM2-binding DUF2616 PF11077.3 ETO14979.1 - 0.0026 17.2 0.7 0.0029 17.1 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2616) Aldose_epim PF01263.15 ETO14979.1 - 0.1 11.6 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Aldose 1-epimerase TPR_11 PF13414.1 ETO14980.1 - 4.1e-07 29.5 0.2 7.5e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 TPR repeat WD40 PF00400.27 ETO14980.1 - 0.00017 21.3 0.9 0.00064 19.4 0.1 2.3 3 0 0 3 3 3 1 WD domain, G-beta repeat TPR_2 PF07719.12 ETO14980.1 - 0.0047 16.7 1.0 3.6 7.7 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO14980.1 - 0.011 15.2 6.1 0.087 12.4 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Nup160 PF11715.3 ETO14980.1 - 0.072 11.2 0.0 0.1 10.7 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 PPR_2 PF13041.1 ETO14981.1 - 1.4e-09 37.7 2.8 3.2e-07 30.2 0.1 2.4 1 1 1 2 2 2 2 PPR repeat family PPR PF01535.15 ETO14981.1 - 1.3e-08 34.2 0.3 0.0018 18.1 0.0 2.6 2 0 0 2 2 2 2 PPR repeat PPR_3 PF13812.1 ETO14981.1 - 6.8e-08 32.2 0.0 0.0052 16.9 0.0 3.2 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 ETO14981.1 - 3.9e-05 23.0 0.1 0.01 15.2 0.0 2.3 2 0 0 2 2 2 2 PPR repeat YycH PF07435.6 ETO14981.1 - 0.015 14.0 0.6 0.02 13.6 0.4 1.2 1 0 0 1 1 1 0 YycH protein YqcI_YcgG PF08892.6 ETO14981.1 - 0.022 14.3 0.2 0.043 13.3 0.1 1.5 1 0 0 1 1 1 0 YqcI/YcgG family MRL1 PF13003.2 ETO14981.1 - 0.029 14.2 0.6 0.049 13.4 0.4 1.4 1 0 0 1 1 1 0 Ribosomal protein L1 GED PF02212.13 ETO14981.1 - 0.14 12.0 2.8 0.16 11.8 0.1 2.3 2 1 1 3 3 3 0 Dynamin GTPase effector domain DUF720 PF05302.6 ETO14982.1 - 0.078 12.7 1.2 0.18 11.5 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF720) Hid1 PF12722.2 ETO14982.1 - 0.16 9.6 11.7 0.22 9.1 8.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Alpha-mann_mid PF09261.6 ETO14982.1 - 0.16 12.1 0.6 0.49 10.6 0.4 1.7 1 0 0 1 1 1 0 Alpha mannosidase, middle domain SprA-related PF12118.3 ETO14982.1 - 2 7.6 15.3 2.7 7.2 10.6 1.1 1 0 0 1 1 1 0 SprA-related family TRC8_N PF13705.1 ETO14983.1 - 0.029 12.9 0.1 0.038 12.5 0.1 1.1 1 0 0 1 1 1 0 TRC8 N-terminal domain Pox_A14 PF05767.7 ETO14984.1 - 0.018 14.9 0.1 0.033 14.1 0.1 1.4 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 WD40 PF00400.27 ETO14985.1 - 2.3e-11 43.1 1.5 5.3e-11 41.9 1.0 1.7 1 0 0 1 1 1 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO14985.1 - 5.2e-06 24.8 0.3 6.2e-06 24.6 0.2 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 WD40 PF00400.27 ETO14986.1 - 1.5e-11 43.7 0.1 1.3e-10 40.7 0.2 2.0 2 0 0 2 2 2 1 WD domain, G-beta repeat CHZ PF09649.5 ETO14986.1 - 0.53 9.5 2.1 0.88 8.8 1.5 1.3 1 0 0 1 1 1 0 Histone chaperone domain CHZ Isy1 PF06246.7 ETO14987.1 - 0.29 10.4 6.2 0.097 12.0 0.6 1.9 1 1 1 2 2 2 0 Isy1-like splicing family GRIN_C PF15235.1 ETO14987.1 - 0.56 10.2 5.1 0.26 11.3 0.4 2.1 1 1 1 2 2 2 0 G protein-regulated inducer of neurite outgrowth C-terminus Dicty_REP PF05086.7 ETO14987.1 - 3.2 5.3 5.6 2.7 5.6 3.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein VWA PF00092.23 ETO14988.1 - 0.003 17.3 0.0 0.0054 16.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain WD40 PF00400.27 ETO14990.1 - 0.0078 16.0 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 WD domain, G-beta repeat TrkH PF02386.11 ETO14990.1 - 0.018 13.6 0.0 0.034 12.7 0.0 1.4 1 1 0 1 1 1 0 Cation transport protein DUF3439 PF11921.3 ETO14990.1 - 0.024 14.3 8.2 0.037 13.7 5.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 ETO14990.1 - 0.047 13.4 11.2 0.063 13.0 7.8 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.7 ETO14990.1 - 0.057 11.1 4.2 0.062 11.0 2.9 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.6 ETO14990.1 - 0.073 11.0 7.6 0.083 10.8 5.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TRP PF06011.7 ETO14991.1 - 4.8e-07 28.7 0.0 5.1e-05 22.0 0.0 2.6 2 1 0 2 2 2 2 Transient receptor potential (TRP) ion channel PH PF00169.24 ETO14991.1 - 0.021 14.9 0.4 2.5 8.3 0.6 3.3 3 0 0 3 3 3 0 PH domain Chlam_PMP PF02415.12 ETO14991.1 - 0.039 14.2 21.5 0.66 10.3 1.5 6.2 6 0 0 6 6 6 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat PolyA_pol_RNAbd PF12627.2 ETO14992.1 - 0.055 13.0 0.2 0.28 10.7 0.1 2.2 2 0 0 2 2 2 0 Probable RNA and SrmB- binding site of polymerase A zf-H2C2_2 PF13465.1 ETO14995.1 - 1.8e-08 34.2 22.3 1.4e-06 28.2 1.2 4.1 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 ETO14995.1 - 0.024 14.9 24.1 0.11 12.8 1.3 4.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 ETO14995.1 - 0.43 10.7 13.2 5.4 7.2 0.6 4.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 ETO14995.1 - 1.5 8.8 16.6 1.3 9.0 0.4 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-AN1 PF01428.11 ETO14995.1 - 1.9 8.4 17.6 0.12 12.3 1.4 3.9 1 1 2 3 3 3 0 AN1-like Zinc finger Zn_Tnp_IS1595 PF12760.2 ETO14995.1 - 5.9 6.7 10.3 27 4.6 3.4 2.8 1 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-C2H2_4 PF13894.1 ETO14995.1 - 8.4 6.9 27.0 4.4 7.8 3.4 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger HCaRG PF07258.9 ETO14996.1 - 3.5e-20 72.2 1.1 4.8e-20 71.8 0.8 1.2 1 0 0 1 1 1 1 HCaRG protein Tryp_alpha_amyl PF00234.17 ETO14996.1 - 0.11 12.7 0.5 0.56 10.4 0.1 2.1 2 0 0 2 2 2 0 Protease inhibitor/seed storage/LTP family LRR_7 PF13504.1 ETO14997.1 - 0.075 13.2 0.1 0.9 10.0 0.1 2.9 1 0 0 1 1 1 0 Leucine rich repeat Secretin PF00263.16 ETO14997.1 - 0.14 11.5 3.3 0.26 10.6 2.3 1.5 1 0 0 1 1 1 0 Bacterial type II and III secretion system protein LRR_1 PF00560.28 ETO14997.1 - 8.6 6.8 7.3 1.2 9.4 0.1 3.6 4 0 0 4 4 4 0 Leucine Rich Repeat Chlam_PMP PF02415.12 ETO14998.1 - 1.6 9.1 0.0 1.6 9.1 0.0 15.6 18 1 0 18 18 18 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat TPR_2 PF07719.12 ETO14999.1 - 0.015 15.1 0.3 0.025 14.4 0.2 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETO14999.1 - 0.044 13.7 0.3 0.073 13.0 0.2 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Apc3 PF12895.2 ETO14999.1 - 0.057 13.5 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 ETO14999.1 - 0.09 12.4 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 TPR repeat Lyase_8 PF02278.13 ETO15000.1 - 0.018 14.4 0.7 0.02 14.2 0.5 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, super-sandwich domain OAD_gamma PF04277.8 ETO15001.1 - 0.57 10.5 4.3 0.42 11.0 0.2 2.5 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain tRNA_synt_1c_R2 PF04557.10 ETO15001.1 - 5.2 7.8 12.6 0.43 11.3 4.9 2.0 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 YajC PF02699.10 ETO15001.1 - 8.4 6.1 7.7 5.4 6.7 0.7 3.6 3 0 0 3 3 3 0 Preprotein translocase subunit DUF2615 PF11027.3 ETO15002.1 - 0.0065 16.3 0.1 0.013 15.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) Amidase PF01425.16 ETO15002.1 - 0.04 12.7 0.4 0.47 9.2 0.0 2.0 2 0 0 2 2 2 0 Amidase HSP70 PF00012.15 ETO15003.1 - 2e-97 326.5 4.8 1.2e-46 158.9 0.0 4.3 4 0 0 4 4 4 4 Hsp70 protein MreB_Mbl PF06723.8 ETO15003.1 - 0.024 13.2 1.2 9.6 4.6 0.0 3.7 4 0 0 4 4 4 0 MreB/Mbl protein RIC3 PF15361.1 ETO15003.1 - 0.24 11.6 0.0 0.24 11.6 0.0 2.8 3 0 0 3 3 3 0 Resistance to inhibitors of cholinesterase homologue 3 WD40 PF00400.27 ETO15005.1 - 5.6e-23 79.9 6.4 6.7e-08 32.1 0.1 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO15005.1 - 0.028 12.5 0.2 0.53 8.3 0.1 2.3 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Kelch_1 PF01344.20 ETO15006.1 - 4.3e-07 29.3 3.9 0.012 15.1 0.2 4.7 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO15006.1 - 1.9e-06 27.5 1.0 0.00088 19.0 0.1 3.5 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO15006.1 - 1.5e-05 24.8 4.0 0.15 12.0 0.0 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 ETO15006.1 - 0.00016 21.7 6.0 0.49 10.6 0.0 4.7 4 1 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO15006.1 - 0.0035 17.0 4.7 0.84 9.5 0.3 3.9 4 1 0 4 4 4 2 Kelch motif Copine PF07002.11 ETO15007.1 - 6.8e-25 87.5 1.3 1e-21 77.2 0.0 2.3 2 0 0 2 2 2 2 Copine Paralemmin PF03285.10 ETO15008.1 - 0.014 14.9 0.4 0.014 14.9 0.3 2.1 2 1 1 3 3 3 0 Paralemmin Macoilin PF09726.4 ETO15008.1 - 8.8 4.4 7.8 12 4.0 5.4 1.2 1 0 0 1 1 1 0 Transmembrane protein CSTF2_hinge PF14327.1 ETO15009.1 - 0.016 15.2 0.4 0.043 13.9 0.1 1.9 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 Endonuc_Holl PF10107.4 ETO15009.1 - 0.052 13.2 0.5 0.55 9.9 0.0 2.1 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Nuc-transf PF10127.4 ETO15009.1 - 0.068 12.5 2.2 0.75 9.0 0.2 2.1 2 0 0 2 2 2 0 Predicted nucleotidyltransferase DUF3439 PF11921.3 ETO15009.1 - 0.84 9.4 4.9 1.9 8.2 3.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) YppF PF14178.1 ETO15009.1 - 2.9 7.4 5.4 17 5.0 0.1 2.8 3 0 0 3 3 3 0 YppF-like protein LRR_6 PF13516.1 ETO15010.1 - 2.1e-16 58.0 9.8 0.018 15.0 0.0 5.3 4 1 1 5 5 5 5 Leucine Rich repeat LRR_1 PF00560.28 ETO15010.1 - 3.3e-08 32.4 2.5 1.7 8.9 0.0 5.5 4 1 0 5 5 5 3 Leucine Rich Repeat LRR_4 PF12799.2 ETO15010.1 - 6.1e-07 28.9 5.5 0.033 13.8 0.1 4.2 3 2 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 ETO15010.1 - 2.9e-06 26.5 8.6 2.1 8.9 0.0 5.4 5 0 0 5 5 5 3 Leucine rich repeat LRR_8 PF13855.1 ETO15010.1 - 1.9e-05 24.3 3.9 0.065 13.0 0.2 3.8 4 1 0 4 4 4 2 Leucine rich repeat DUF2514 PF10721.4 ETO15012.1 - 0.0084 15.8 3.0 0.0084 15.8 2.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2514) Atg14 PF10186.4 ETO15012.1 - 0.014 14.3 0.2 0.016 14.1 0.1 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 RapA_C PF12137.3 ETO15012.1 - 0.019 13.8 1.4 0.025 13.4 1.0 1.1 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal RCSD PF05177.7 ETO15012.1 - 0.03 14.8 9.4 0.046 14.2 6.5 1.4 1 1 0 1 1 1 0 RCSD region Rtf2 PF04641.7 ETO15012.1 - 0.031 13.4 6.0 0.039 13.1 4.2 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Tox-REase-3 PF15647.1 ETO15012.1 - 0.058 13.1 1.5 0.08 12.7 1.1 1.3 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 3 CRISPR_Cse2 PF09485.5 ETO15012.1 - 0.062 13.3 1.2 0.11 12.4 0.3 1.7 1 1 1 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) DUF3138 PF11336.3 ETO15012.1 - 0.2 9.7 1.1 0.22 9.6 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Seryl_tRNA_N PF02403.17 ETO15012.1 - 0.21 11.6 5.4 0.45 10.5 3.7 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain zf-C4H2 PF10146.4 ETO15012.1 - 0.22 11.4 3.6 0.28 11.1 2.5 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein PGA2 PF07543.7 ETO15012.1 - 0.4 10.4 8.0 0.19 11.5 3.5 1.9 1 1 1 2 2 2 0 Protein trafficking PGA2 Asp-B-Hydro_N PF05279.6 ETO15012.1 - 0.51 10.1 7.4 0.63 9.8 5.1 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Peptidase_S49_N PF08496.5 ETO15012.1 - 1.7 8.3 7.1 4.2 7.1 4.8 1.8 1 1 1 2 2 2 0 Peptidase family S49 N-terminal Seryl_tRNA_N PF02403.17 ETO15013.1 - 0.00013 21.9 25.9 0.12 12.3 0.5 4.1 3 1 1 4 4 4 2 Seryl-tRNA synthetase N-terminal domain HrpB2 PF09487.5 ETO15013.1 - 0.002 18.3 2.5 0.002 18.3 1.7 2.1 1 1 1 2 2 2 1 Bacterial type III secretion protein (HrpB2) DivIC PF04977.10 ETO15013.1 - 0.021 14.2 29.4 0.17 11.4 2.7 4.6 3 1 0 4 4 4 0 Septum formation initiator Coat_F PF07875.7 ETO15013.1 - 0.053 13.6 5.0 0.092 12.8 1.4 2.4 2 0 0 2 2 2 0 Coat F domain DUF869 PF05911.6 ETO15013.1 - 0.26 9.4 27.5 0.32 9.1 11.6 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) Phage_GP20 PF06810.6 ETO15013.1 - 0.29 10.5 39.4 2.4 7.5 3.1 4.0 2 1 2 4 4 4 0 Phage minor structural protein GP20 Filament PF00038.16 ETO15013.1 - 0.29 10.5 31.9 0.4 10.1 6.3 3.2 1 1 2 3 3 3 0 Intermediate filament protein CENP-F_leu_zip PF10473.4 ETO15013.1 - 0.33 10.7 36.1 0.92 9.3 3.2 3.2 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.16 ETO15013.1 - 0.38 10.7 26.5 0.41 10.6 1.8 4.8 3 1 2 5 5 5 0 bZIP transcription factor TSC22 PF01166.13 ETO15013.1 - 0.39 10.7 18.8 3.7 7.5 0.4 4.4 4 1 0 4 4 4 0 TSC-22/dip/bun family Herpes_BLRF2 PF05812.7 ETO15013.1 - 0.48 10.2 21.8 0.44 10.3 0.8 3.3 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein Mto2_bdg PF12808.2 ETO15013.1 - 0.5 10.5 19.6 3.4 7.8 0.7 4.0 4 0 0 4 4 4 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Tropomyosin_1 PF12718.2 ETO15013.1 - 0.54 10.0 35.6 0.44 10.3 5.9 3.7 1 1 2 3 3 3 0 Tropomyosin like TMF_TATA_bd PF12325.3 ETO15013.1 - 0.64 9.7 30.1 0.18 11.5 0.3 4.1 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding Fib_alpha PF08702.5 ETO15013.1 - 0.79 9.8 26.3 0.62 10.1 6.1 2.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family ATG16 PF08614.6 ETO15013.1 - 0.91 9.3 34.8 5.8 6.6 3.0 3.1 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.3 ETO15013.1 - 1 9.1 31.9 0.043 13.6 2.4 4.6 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.7 ETO15013.1 - 1.4 8.6 37.9 0.24 11.1 1.9 3.4 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DivIVA PF05103.8 ETO15013.1 - 1.5 8.8 31.8 9.2 6.3 1.3 4.1 2 1 1 4 4 4 0 DivIVA protein Atg14 PF10186.4 ETO15013.1 - 1.8 7.4 27.8 0.066 12.1 10.9 2.3 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF904 PF06005.7 ETO15013.1 - 6 7.2 39.1 0.053 13.8 2.8 4.7 2 1 0 2 2 1 0 Protein of unknown function (DUF904) DUF4140 PF13600.1 ETO15013.1 - 7.6 7.0 22.7 0.13 12.7 1.2 4.3 2 1 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) Reo_sigmaC PF04582.7 ETO15013.1 - 9.1 5.3 7.0 5 6.2 0.8 2.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF972 PF06156.8 ETO15013.1 - 9.4 6.6 30.3 2.8 8.3 1.9 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF972) Seryl_tRNA_N PF02403.17 ETO15014.1 - 0.019 14.9 9.7 0.032 14.2 3.3 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3373 PF11853.3 ETO15014.1 - 0.06 11.8 1.9 0.073 11.5 1.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) OTU PF02338.14 ETO15014.1 - 0.11 13.1 3.2 0.39 11.3 2.2 1.9 1 1 0 1 1 1 0 OTU-like cysteine protease BDV_P24 PF06595.6 ETO15014.1 - 0.13 12.0 4.1 0.15 11.8 2.6 1.3 1 1 0 1 1 1 0 Borna disease virus P24 protein DUF3573 PF12097.3 ETO15014.1 - 0.13 10.8 2.5 0.15 10.6 1.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) SVM_signal PF12113.3 ETO15014.1 - 0.18 11.6 2.2 0.36 10.7 1.6 1.4 1 0 0 1 1 1 0 SVM protein signal sequence DUF2433 PF10360.4 ETO15014.1 - 0.19 12.0 1.2 0.24 11.6 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2433) IncA PF04156.9 ETO15014.1 - 0.36 10.3 8.2 0.48 9.9 5.7 1.2 1 0 0 1 1 1 0 IncA protein Med11 PF10280.4 ETO15014.1 - 0.91 9.5 6.9 1.9 8.5 4.8 1.6 1 1 0 1 1 1 0 Mediator complex protein CCDC-167 PF15188.1 ETO15014.1 - 1.6 8.7 8.4 5.7 6.9 5.8 2.1 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Ribosomal_L29 PF00831.18 ETO15014.1 - 2.3 7.9 8.6 0.71 9.6 3.1 2.5 2 1 0 2 2 2 0 Ribosomal L29 protein Histone_HNS PF00816.16 ETO15014.1 - 2.8 8.5 5.6 3.3 8.2 2.9 1.8 1 1 0 1 1 1 0 H-NS histone family FlaC_arch PF05377.6 ETO15014.1 - 2.8 7.8 9.2 8.9 6.2 1.0 2.9 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) Spc24 PF08286.6 ETO15014.1 - 7.5 6.2 10.1 5.4 6.7 5.0 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DnaB_2 PF07261.6 ETO15016.1 - 0.09 12.3 1.2 0.19 11.3 0.8 1.5 1 0 0 1 1 1 0 Replication initiation and membrane attachment TLD PF07534.11 ETO15017.1 - 3.7e-30 104.7 0.8 9.9e-30 103.3 0.5 1.8 1 0 0 1 1 1 1 TLD PH_BEACH PF14844.1 ETO15017.1 - 0.0045 16.8 0.2 1.8 8.4 0.0 2.9 2 0 0 2 2 2 2 PH domain associated with Beige/BEACH FAT PF02259.18 ETO15019.1 - 0.0029 16.6 0.0 0.014 14.3 0.0 1.8 1 1 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 ETO15020.1 - 2.4e-41 141.7 1.9 4.3e-41 140.9 1.3 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 ETO15020.1 - 7.3e-13 47.7 0.1 1.4e-12 46.7 0.1 1.5 1 0 0 1 1 1 1 FATC domain YlbD_coat PF14071.1 ETO15021.1 - 0.029 14.4 0.4 0.09 12.8 0.3 1.8 1 0 0 1 1 1 0 Putative coat protein Syntaxin-18_N PF10496.4 ETO15021.1 - 2.3 8.0 8.8 0.21 11.4 0.5 2.8 2 1 1 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus DUF3908 PF13048.1 ETO15022.1 - 0.21 11.5 4.2 10 6.0 0.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3908) Macro PF01661.16 ETO15023.1 - 0.089 12.7 0.3 2.1 8.2 0.0 2.5 3 0 0 3 3 3 0 Macro domain zf-DNL PF05180.7 ETO15024.1 - 8.3e-19 67.0 1.8 2.2e-18 65.6 1.3 1.7 1 0 0 1 1 1 1 DNL zinc finger S-AdoMet_synt_M PF02772.11 ETO15024.1 - 0.027 14.4 0.4 5.6 6.9 0.0 2.3 2 1 0 2 2 2 0 S-adenosylmethionine synthetase, central domain pRN1_helical PF13010.1 ETO15024.1 - 0.039 13.5 11.0 0.6 9.7 0.5 3.1 1 1 2 3 3 3 0 Primase helical domain Elf1 PF05129.8 ETO15024.1 - 0.57 9.9 5.5 0.27 10.9 1.9 2.0 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Tubulin_C PF03953.12 ETO15025.1 - 1.3e-29 102.8 0.0 1.9e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 ETO15025.1 - 5.7e-27 94.9 0.1 1.1e-26 93.9 0.1 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain RhoGEF PF00621.15 ETO15026.1 - 1.1e-15 58.0 8.0 1.6e-15 57.4 5.6 1.2 1 0 0 1 1 1 1 RhoGEF domain Phi-29_GP3 PF05435.6 ETO15026.1 - 0.00047 19.4 4.9 0.00065 19.0 3.2 1.4 1 1 0 1 1 1 1 Phi-29 DNA terminal protein GP3 Tubulin_C PF03953.12 ETO15027.1 - 0.0067 16.4 0.0 0.009 16.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 ETO15027.1 - 0.0092 15.8 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain WD40 PF00400.27 ETO15028.1 - 3e-32 109.3 13.8 9.3e-11 41.1 1.7 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO15028.1 - 5.6e-06 24.7 2.0 0.00017 19.8 0.4 2.7 1 1 0 2 2 2 2 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO15028.1 - 0.17 11.1 5.4 0.31 10.3 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4221) DUF3769 PF12600.3 ETO15030.1 - 0.075 11.8 2.9 0.24 10.1 2.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3769) CENP-B_dimeris PF09026.5 ETO15030.1 - 0.22 11.8 7.3 0.15 12.3 2.4 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF3439 PF11921.3 ETO15030.1 - 1.6 8.4 6.7 2.6 7.8 2.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) ATAD4 PF15321.1 ETO15030.1 - 2.8 9.0 10.4 0.075 14.0 1.0 2.6 2 1 0 2 2 2 0 ATPase family AAA domain containing 4 PBP1_TM PF14812.1 ETO15030.1 - 7.9 6.8 9.1 7.4 6.9 2.9 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ank_2 PF12796.2 ETO15031.1 - 3.3e-19 69.0 4.0 7.1e-13 48.7 0.1 3.7 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO15031.1 - 1.5e-14 54.0 2.0 0.00015 22.1 0.4 5.0 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 ETO15031.1 - 1.7e-14 52.8 0.0 0.0004 20.0 0.1 4.3 3 1 0 3 3 3 3 Ankyrin repeat DEP PF00610.16 ETO15031.1 - 4.6e-14 51.9 0.1 2.9e-13 49.3 0.0 2.3 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Ank_5 PF13857.1 ETO15031.1 - 1.2e-11 44.4 15.6 3.5e-05 23.9 0.1 5.4 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO15031.1 - 1.3e-06 28.0 7.0 0.041 14.1 0.1 5.1 6 0 0 6 6 6 2 Ankyrin repeat Ank_2 PF12796.2 ETO15032.1 - 2.7e-44 149.4 7.9 1.2e-20 73.6 0.7 4.2 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 ETO15032.1 - 3.1e-39 130.8 16.8 2.6e-07 30.1 0.0 7.6 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 ETO15032.1 - 1.2e-32 111.1 13.0 1.3e-07 31.6 0.3 7.3 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO15032.1 - 3.6e-27 91.7 6.8 0.0029 17.6 0.1 8.1 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 ETO15032.1 - 4.7e-27 93.8 8.4 6.2e-10 39.3 0.1 6.3 1 1 6 7 7 7 5 Ankyrin repeats (many copies) SIR2 PF02146.12 ETO15033.1 - 0.081 12.6 1.0 0.2 11.3 0.2 1.9 2 0 0 2 2 2 0 Sir2 family DUF3899 PF13038.1 ETO15034.1 - 3.8 7.7 8.2 4.5 7.4 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) SR-25 PF10500.4 ETO15034.1 - 6.2 6.2 13.6 9.3 5.6 9.4 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF285 PF03382.9 ETO15035.1 - 0.027 14.0 0.6 0.055 13.0 0.4 1.5 1 0 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 DUF3121 PF11319.3 ETO15035.1 - 0.26 10.7 7.4 0.09 12.2 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3121) DUF4342 PF14242.1 ETO15035.1 - 1.2 8.9 5.6 2.8 7.7 3.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4342) DUF3332 PF11810.3 ETO15035.1 - 1.3 8.7 7.4 1.9 8.1 5.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) DUF2115 PF09888.4 ETO15035.1 - 2.2 8.3 9.2 1 9.4 3.6 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) TPR_12 PF13424.1 ETO15036.1 - 1.1e-25 89.3 0.6 1.3e-14 53.8 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO15036.1 - 2.1e-20 72.0 14.1 6.8e-12 44.8 0.4 2.5 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 ETO15036.1 - 8.5e-17 59.6 2.4 1e-05 25.0 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO15036.1 - 1e-14 53.3 11.8 3.5e-09 35.8 0.2 4.3 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO15036.1 - 3.8e-13 48.2 9.1 0.00016 21.2 0.3 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO15036.1 - 4.9e-13 47.8 1.1 0.0012 18.5 0.0 3.9 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO15036.1 - 1.2e-09 37.7 0.0 0.0093 15.8 0.0 3.6 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO15036.1 - 6.3e-09 35.7 0.9 0.069 13.6 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat SNAP PF14938.1 ETO15036.1 - 1.4e-07 30.9 0.6 2.2e-07 30.3 0.4 1.3 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_17 PF13431.1 ETO15036.1 - 3.5e-06 26.7 1.3 0.26 11.5 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO15036.1 - 4.6e-05 23.6 0.0 0.67 10.7 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO15036.1 - 0.00015 22.3 0.0 0.21 12.3 0.0 2.8 3 1 1 4 4 3 1 Tetratricopeptide repeat MIT PF04212.13 ETO15036.1 - 0.00032 20.5 0.2 0.019 14.8 0.1 2.7 2 1 0 2 2 2 1 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 ETO15036.1 - 0.018 15.1 3.0 0.18 11.9 0.2 2.9 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Sel1 PF08238.7 ETO15036.1 - 0.02 15.5 2.2 9.6 6.9 0.0 3.3 3 0 0 3 3 3 0 Sel1 repeat TPR_19 PF14559.1 ETO15036.1 - 0.071 13.4 0.0 3.9 7.8 0.0 3.1 3 1 1 4 4 3 0 Tetratricopeptide repeat Peptidase_C26 PF07722.8 ETO15037.1 - 8.2e-16 58.0 0.0 8.5e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase C26 GATase PF00117.23 ETO15037.1 - 0.0002 20.8 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I WD40 PF00400.27 ETO15038.1 - 1.9e-12 46.5 5.9 3.9e-09 36.0 0.1 2.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO15038.1 - 0.044 11.9 0.4 0.067 11.3 0.1 1.5 1 1 1 2 2 2 0 Nucleoporin Nup120/160 DUF1510 PF07423.6 ETO15039.1 - 0.0012 18.2 0.3 0.0014 18.0 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) 7TM_GPCR_Srv PF10323.4 ETO15039.1 - 0.11 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv LAM_C PF12544.3 ETO15039.1 - 0.26 11.3 1.7 0.34 10.9 1.2 1.1 1 0 0 1 1 1 0 Lysine-2,3-aminomutase Peptidase_S49_N PF08496.5 ETO15039.1 - 1.1 9.0 6.6 1.6 8.5 4.6 1.3 1 1 0 1 1 1 0 Peptidase family S49 N-terminal EphA2_TM PF14575.1 ETO15039.1 - 2.3 8.6 5.1 14 6.1 3.6 2.2 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Exo_endo_phos PF03372.18 ETO15040.1 - 0.0016 18.4 0.0 0.014 15.3 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BcrAD_BadFG PF01869.15 ETO15040.1 - 0.063 12.5 0.0 0.079 12.2 0.0 1.0 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Sec62 PF03839.11 ETO15040.1 - 0.27 10.5 5.1 0.35 10.2 3.6 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF904 PF06005.7 ETO15040.1 - 0.63 10.3 6.0 1.1 9.6 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF4512 PF14975.1 ETO15040.1 - 0.7 10.7 4.8 1.2 9.9 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) CAP_GLY PF01302.20 ETO15042.1 - 7.3e-08 31.9 0.2 1.4e-07 31.1 0.1 1.4 1 1 0 1 1 1 1 CAP-Gly domain MIP-T3 PF10243.4 ETO15042.1 - 0.0012 17.3 3.0 0.0012 17.3 2.1 1.0 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CENP-B_dimeris PF09026.5 ETO15042.1 - 0.39 10.9 6.9 0.59 10.4 4.7 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain UBA_4 PF14555.1 ETO15043.1 - 0.017 14.6 0.1 0.031 13.8 0.1 1.4 1 0 0 1 1 1 0 UBA-like domain LA-virus_coat PF09220.5 ETO15044.1 - 0.044 12.2 0.0 0.084 11.3 0.0 1.3 1 0 0 1 1 1 0 L-A virus, major coat protein UNC45-central PF11701.3 ETO15045.1 - 0.0089 15.6 8.8 0.95 9.0 0.1 3.4 3 0 0 3 3 3 2 Myosin-binding striated muscle assembly central Arm PF00514.18 ETO15045.1 - 0.032 14.0 10.0 0.15 11.9 0.1 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat SprA-related PF12118.3 ETO15046.1 - 5.3 6.2 18.0 8.1 5.6 12.5 1.2 1 0 0 1 1 1 0 SprA-related family Tubulin PF00091.20 ETO15049.1 - 7.9e-44 150.0 0.0 8.8e-44 149.9 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain WD40 PF00400.27 ETO15050.1 - 1.8e-21 75.1 1.8 7.6e-10 38.3 0.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO15050.1 - 0.00027 19.8 2.8 0.022 13.5 0.1 2.1 1 1 1 2 2 2 2 Nup133 N terminal like Daxx PF03344.10 ETO15051.1 - 0.4 9.1 17.8 0.5 8.7 12.4 1.2 1 0 0 1 1 1 0 Daxx Family PBP1_TM PF14812.1 ETO15051.1 - 0.4 11.0 0.2 0.4 11.0 0.1 2.7 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2201_N PF13203.1 ETO15051.1 - 0.59 9.2 5.4 0.73 8.9 3.7 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Pneumo_att_G PF05539.6 ETO15051.1 - 1.5 8.1 7.3 2.1 7.6 5.1 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G NST1 PF13945.1 ETO15051.1 - 6.9 6.7 9.1 2.8 7.9 4.5 1.6 1 1 1 2 2 2 0 Salt tolerance down-regulator Hid1 PF12722.2 ETO15051.1 - 8.4 3.9 8.4 9.1 3.8 5.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein WD40 PF00400.27 ETO15052.1 - 2.5e-19 68.3 7.8 1.1e-09 37.7 0.9 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO15052.1 - 0.00011 20.5 1.5 0.0047 15.1 0.1 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 DUF4164 PF13747.1 ETO15052.1 - 0.89 9.7 10.4 1.8 8.7 0.2 2.9 1 1 1 3 3 3 0 Domain of unknown function (DUF4164) Hema_stalk PF08720.5 ETO15052.1 - 4.7 6.6 8.4 1.4 8.4 1.5 2.3 1 1 1 2 2 2 0 Influenza C hemagglutinin stalk zf-C3HC4_2 PF13923.1 ETO15054.1 - 0.0088 16.0 0.9 0.0088 16.0 0.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO15054.1 - 0.024 14.4 0.8 0.083 12.7 0.6 2.0 1 0 0 1 1 1 0 Ring finger domain Mss4 PF04421.8 ETO15054.1 - 0.054 13.3 0.2 0.054 13.3 0.1 2.6 3 0 0 3 3 3 0 Mss4 protein WD40 PF00400.27 ETO15055.1 - 4.3e-50 165.8 15.4 5.8e-11 41.8 0.2 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat PD40 PF07676.7 ETO15055.1 - 6.2e-08 32.1 1.2 0.0082 15.7 0.0 4.6 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Kelch_1 PF01344.20 ETO15055.1 - 1.1e-05 24.8 4.5 0.0019 17.6 0.3 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO15055.1 - 0.00065 19.7 4.7 0.39 10.9 0.3 3.8 3 0 0 3 3 3 2 Kelch motif Nbas_N PF15492.1 ETO15055.1 - 0.00091 18.4 2.4 0.73 8.8 0.2 3.9 2 1 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Kelch_4 PF13418.1 ETO15055.1 - 0.0046 16.6 0.0 0.061 13.1 0.0 3.0 2 0 0 2 2 2 1 Galactose oxidase, central domain PQQ_2 PF13360.1 ETO15055.1 - 0.0052 16.2 1.2 0.0087 15.5 0.0 1.9 2 1 0 2 2 2 1 PQQ-like domain GF_recep_IV PF14843.1 ETO15055.1 - 0.013 15.1 0.7 0.039 13.5 0.5 1.8 1 0 0 1 1 1 0 Growth factor receptor domain IV Kelch_3 PF13415.1 ETO15055.1 - 0.022 14.9 0.0 0.23 11.6 0.0 2.7 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO15055.1 - 0.044 13.7 0.1 1.4 8.9 0.1 3.0 3 0 0 3 3 3 0 Kelch motif WD40 PF00400.27 ETO15056.1 - 8.2e-33 111.0 7.9 7.9e-12 44.5 0.2 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO15056.1 - 5.5e-08 31.3 0.7 0.001 17.2 0.1 3.0 2 1 1 3 3 3 3 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO15056.1 - 0.011 15.5 0.4 0.026 14.2 0.2 1.7 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Pkinase_C PF00433.19 ETO15057.1 - 3.8e-07 30.5 0.3 5.5e-07 30.0 0.2 1.3 1 0 0 1 1 1 1 Protein kinase C terminal domain Pkinase PF00069.20 ETO15057.1 - 0.01 15.0 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Phage_holin_6 PF10746.4 ETO15057.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.5 2 0 0 2 2 2 0 Phage holin family 6 Pkinase PF00069.20 ETO15058.1 - 6.1e-42 143.5 0.8 7.8e-41 139.9 0.5 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO15058.1 - 7.7e-19 67.7 0.0 1.5e-15 56.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 ETO15058.1 - 0.039 12.9 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETO15058.1 - 0.042 12.8 0.0 0.068 12.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like F-protein PF00469.15 ETO15059.1 - 0.08 12.2 0.0 0.097 12.0 0.0 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Pkinase PF00069.20 ETO15061.1 - 6.8e-08 31.9 0.0 1.5e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO15061.1 - 0.0022 17.1 0.3 0.0046 16.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase DUF2701 PF10857.3 ETO15062.1 - 0.073 12.8 2.3 0.15 11.8 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2701) YolD PF08863.5 ETO15062.1 - 0.16 11.8 6.0 0.21 11.4 4.1 1.2 1 0 0 1 1 1 0 YolD-like protein DsrD PF08679.6 ETO15062.1 - 1.6 8.8 4.8 0.28 11.2 0.9 1.8 2 1 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) DUF3807 PF12720.2 ETO15063.1 - 0.65 10.1 10.2 1.2 9.3 7.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) GPS PF01825.16 ETO15066.1 - 0.0094 16.0 1.3 0.0094 16.0 0.9 1.7 2 0 0 2 2 2 1 Latrophilin/CL-1-like GPS domain Phage_X PF05155.10 ETO15068.1 - 0.022 14.6 0.2 7.4 6.5 0.0 2.9 3 0 0 3 3 3 0 Phage X family HsbA PF12296.3 ETO15068.1 - 0.023 14.5 0.1 0.06 13.2 0.0 1.7 1 0 0 1 1 1 0 Hydrophobic surface binding protein A Mer2 PF09074.5 ETO15068.1 - 0.026 14.4 15.7 0.74 9.7 4.2 3.1 1 1 1 2 2 2 0 Mer2 Mitofilin PF09731.4 ETO15068.1 - 0.071 11.7 9.0 0.24 10.0 1.6 2.0 1 1 1 2 2 2 0 Mitochondrial inner membrane protein DrsE_2 PF13686.1 ETO15068.1 - 0.079 12.7 0.6 0.23 11.2 0.2 1.9 2 0 0 2 2 2 0 DsrE/DsrF/DrsH-like family LON PF02190.11 ETO15068.1 - 0.78 9.3 3.9 0.72 9.4 0.6 2.0 1 1 1 2 2 2 0 ATP-dependent protease La (LON) domain SBP_bac_7 PF03480.8 ETO15068.1 - 3.3 6.7 6.4 0.82 8.7 0.1 2.4 2 1 1 3 3 3 0 Bacterial extracellular solute-binding protein, family 7 ZZ PF00569.12 ETO15069.1 - 0.0032 16.9 0.7 0.0067 15.9 0.5 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type DUF3783 PF12646.2 ETO15069.1 - 0.0044 16.7 0.3 0.26 11.0 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3783) WD40 PF00400.27 ETO15070.1 - 5e-55 181.5 18.4 6.5e-10 38.4 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO15070.1 - 3.2e-10 38.7 6.0 0.002 16.3 0.2 5.3 1 1 5 6 6 6 5 Nucleoporin Nup120/160 CH PF00307.26 ETO15070.1 - 4.3e-10 39.5 0.5 4.3e-10 39.5 0.3 2.3 2 0 0 2 2 2 1 Calponin homology (CH) domain WD40 PF00400.27 ETO15072.1 - 5.4e-50 165.5 23.5 4e-12 45.5 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO15072.1 - 6.7e-07 27.8 0.9 1.4 6.9 0.0 4.9 2 1 3 5 5 5 4 Nucleoporin Nup120/160 zf-C3HC4_2 PF13923.1 ETO15073.1 - 0.098 12.7 0.8 0.098 12.7 0.5 3.5 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) BHD_1 PF10403.4 ETO15073.1 - 0.3 10.6 1.7 0.51 9.9 0.2 2.1 2 1 0 2 2 2 0 Rad4 beta-hairpin domain 1 CAP_GLY PF01302.20 ETO15075.1 - 0.026 14.2 0.0 0.87 9.3 0.0 2.5 1 1 0 1 1 1 0 CAP-Gly domain ABC_tran PF00005.22 ETO15077.1 - 9.3e-14 51.8 0.0 1.7e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 ETO15077.1 - 0.064 13.2 0.3 0.14 12.1 0.2 1.7 1 1 0 1 1 1 0 AAA domain FragX_IP PF05994.6 ETO15078.1 - 2.8e-157 524.8 0.4 4.3e-157 524.3 0.3 1.2 1 0 0 1 1 1 1 Cytoplasmic Fragile-X interacting family YTH PF04146.10 ETO15079.1 - 0.057 13.0 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 YT521-B-like domain ABC2_membrane PF01061.19 ETO15080.1 - 2.9e-11 42.9 6.7 3.9e-11 42.5 4.7 1.1 1 0 0 1 1 1 1 ABC-2 type transporter FYVE_2 PF02318.11 ETO15080.1 - 0.067 13.0 0.3 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger CCDC155 PF14662.1 ETO15082.1 - 0.00055 19.5 2.1 0.00098 18.7 1.4 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 DUF904 PF06005.7 ETO15082.1 - 0.0019 18.4 3.5 0.0019 18.4 2.4 2.0 2 1 0 2 2 1 1 Protein of unknown function (DUF904) HALZ PF02183.13 ETO15082.1 - 0.0025 17.4 3.9 0.0044 16.7 2.7 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper bZIP_1 PF00170.16 ETO15082.1 - 0.0039 17.1 3.1 0.0085 16.0 2.2 1.6 1 0 0 1 1 1 1 bZIP transcription factor DUF972 PF06156.8 ETO15082.1 - 0.0039 17.5 1.5 0.0039 17.5 1.0 2.3 2 1 0 2 2 1 1 Protein of unknown function (DUF972) DivIC PF04977.10 ETO15082.1 - 0.011 15.2 1.7 0.024 14.1 1.2 1.6 1 0 0 1 1 1 0 Septum formation initiator Syntaxin PF00804.20 ETO15082.1 - 0.03 14.4 0.6 0.03 14.4 0.4 2.4 2 1 0 2 2 1 0 Syntaxin AKNA PF12443.3 ETO15082.1 - 0.054 13.5 0.6 0.13 12.2 0.4 1.6 1 0 0 1 1 1 0 AT-hook-containing transcription factor DMPK_coil PF08826.5 ETO15082.1 - 0.077 12.9 1.5 0.17 11.8 1.1 1.6 1 0 0 1 1 1 0 DMPK coiled coil domain like DUF1875 PF08961.5 ETO15082.1 - 0.086 12.1 2.7 0.096 11.9 1.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1875) DUF3450 PF11932.3 ETO15082.1 - 0.22 10.7 3.8 0.08 12.1 1.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Ribosomal_L29 PF00831.18 ETO15082.1 - 0.28 10.8 4.7 0.62 9.7 3.3 1.6 1 1 0 1 1 1 0 Ribosomal L29 protein Macoilin PF09726.4 ETO15082.1 - 0.47 8.6 19.5 0.61 8.3 13.5 1.1 1 0 0 1 1 1 0 Transmembrane protein bZIP_2 PF07716.10 ETO15082.1 - 0.71 9.7 6.1 1.2 9.0 2.2 2.2 1 1 2 3 3 3 0 Basic region leucine zipper DUF913 PF06025.7 ETO15082.1 - 0.75 8.4 6.2 0.91 8.2 4.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Tmemb_cc2 PF10267.4 ETO15082.1 - 0.76 8.3 13.9 0.99 7.9 9.6 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein SpoIIIAH PF12685.2 ETO15082.1 - 1.2 8.6 14.3 1.5 8.2 9.9 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein RAP1 PF07218.6 ETO15082.1 - 1.8 6.5 15.5 2.2 6.2 10.7 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF2146 PF10220.4 ETO15082.1 - 3.6 5.4 10.1 3.5 5.5 7.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) SprA-related PF12118.3 ETO15082.1 - 5 6.3 15.9 5.8 6.1 11.0 1.1 1 0 0 1 1 1 0 SprA-related family UPF0449 PF15136.1 ETO15082.1 - 5.2 7.3 6.7 23 5.2 4.6 2.3 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 TMF_DNA_bd PF12329.3 ETO15082.1 - 8.3 6.3 12.3 0.064 13.0 1.9 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Neur_chan_memb PF02932.11 ETO15082.1 - 8.8 6.1 7.0 9.6 6.0 4.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DivIVA PF05103.8 ETO15082.1 - 9.3 6.3 12.8 0.092 12.7 1.4 2.3 1 1 0 2 2 2 0 DivIVA protein PH PF00169.24 ETO15083.1 - 2.9e-09 37.0 0.2 4.2e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 PH domain FYVE PF01363.16 ETO15083.1 - 4.8e-05 23.1 0.8 8.6e-05 22.3 0.6 1.4 1 0 0 1 1 1 1 FYVE zinc finger PH_11 PF15413.1 ETO15083.1 - 0.023 14.9 0.0 0.054 13.7 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain FYVE_2 PF02318.11 ETO15084.1 - 0.0097 15.8 3.6 0.0097 15.8 2.5 3.8 3 2 0 3 3 3 1 FYVE-type zinc finger Pox_A_type_inc PF04508.7 ETO15084.1 - 1.8 8.5 9.7 0.46 10.3 2.4 3.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat RhoGEF PF00621.15 ETO15086.1 - 0.00058 19.7 1.3 0.00063 19.6 0.2 1.6 2 0 0 2 2 2 1 RhoGEF domain Phage_tube PF04985.9 ETO15086.1 - 0.12 11.8 1.2 0.16 11.3 0.9 1.1 1 0 0 1 1 1 0 Phage tail tube protein FII Dicty_REP PF05086.7 ETO15086.1 - 0.47 8.1 10.5 0.6 7.8 7.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3291 PF11695.3 ETO15087.1 - 0.0039 16.6 0.3 0.0093 15.3 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3291) Saccharop_dh PF03435.13 ETO15087.1 - 0.15 11.0 2.1 3.9 6.3 0.1 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase SURF6 PF04935.7 ETO15088.1 - 8.5e-09 35.0 12.3 8.5e-09 35.0 8.5 1.5 2 0 0 2 2 2 1 Surfeit locus protein 6 AgrB PF04647.10 ETO15088.1 - 0.025 13.6 1.4 0.041 12.9 1.0 1.3 1 0 0 1 1 1 0 Accessory gene regulator B DUF3884 PF13024.1 ETO15088.1 - 0.03 13.7 0.1 0.064 12.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3884) DUF2358 PF10184.4 ETO15089.1 - 0.012 15.5 0.4 0.046 13.6 0.1 1.9 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2358) Ribosomal_S4 PF00163.14 ETO15091.1 - 6.3e-19 68.1 1.0 1.5e-18 66.9 0.7 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 ETO15091.1 - 6.3e-07 28.7 0.8 6.3e-07 28.7 0.6 1.9 2 0 0 2 2 2 1 S4 domain Spore_YhcN_YlaJ PF09580.5 ETO15091.1 - 0.069 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) MatK_N PF01824.13 ETO15091.1 - 0.22 10.5 1.4 1.3 8.0 0.2 2.0 2 0 0 2 2 2 0 MatK/TrnK amino terminal region Nbl1_Borealin_N PF10444.4 ETO15092.1 - 0.0053 16.1 0.4 3.1 7.2 0.0 2.6 2 0 0 2 2 2 2 Nbl1 / Borealin N terminal Bud13 PF09736.4 ETO15093.1 - 0.45 10.7 7.5 0.62 10.3 5.2 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF4200 PF13863.1 ETO15093.1 - 0.91 9.4 11.7 0.66 9.9 6.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) WD40 PF00400.27 ETO15094.1 - 1e-128 415.1 37.2 5.6e-12 45.0 0.0 13.7 14 0 0 14 14 14 13 WD domain, G-beta repeat Nup160 PF11715.3 ETO15094.1 - 1.4e-21 76.2 22.3 0.0075 14.4 0.0 10.1 3 2 7 10 10 10 9 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO15094.1 - 8.6e-06 25.3 7.0 0.00023 20.7 0.3 4.5 2 2 1 3 3 3 1 PQQ-like domain DUF3601 PF12208.3 ETO15094.1 - 1.2e-05 25.1 0.0 1 9.3 0.0 6.8 5 2 4 9 9 9 1 Domain of unknown function (DUF3601) Proteasome_A_N PF10584.4 ETO15094.1 - 6.1 6.2 5.0 59 3.1 0.0 3.9 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature zf-TRAF PF02176.13 ETO15095.1 - 0.00028 21.2 2.0 0.00028 21.2 1.4 2.7 2 1 1 3 3 3 1 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 ETO15095.1 - 4.3 7.4 11.8 1.7 8.7 1.7 3.5 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) YMF19 PF02326.10 ETO15096.1 - 0.00075 20.0 3.9 0.0012 19.4 2.7 1.3 1 0 0 1 1 1 1 Plant ATP synthase F0 DUF883 PF05957.8 ETO15098.1 - 3.2 8.1 10.2 9.2 6.7 0.4 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Pup PF05639.6 ETO15099.1 - 0.33 11.4 9.1 5.7 7.5 6.3 2.2 1 1 0 1 1 1 0 Pup-like protein Menin PF05053.8 ETO15099.1 - 3.7 5.5 12.0 4.3 5.3 8.3 1.0 1 0 0 1 1 1 0 Menin SOG2 PF10428.4 ETO15099.1 - 6 5.4 9.6 6.6 5.2 6.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Clat_adaptor_s PF01217.15 ETO15100.1 - 1.3e-51 174.0 3.9 1.6e-51 173.7 2.7 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain NCD2 PF04905.8 ETO15100.1 - 0.076 12.8 1.5 0.93 9.2 0.0 2.1 2 0 0 2 2 2 0 NAB conserved region 2 (NCD2) U3_assoc_6 PF08640.6 ETO15100.1 - 0.11 12.2 2.9 0.19 11.4 0.3 2.2 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 chaperone_DMP PF10448.4 ETO15101.1 - 0.031 14.1 0.8 0.11 12.4 0.1 2.3 2 0 0 2 2 2 0 20S proteasome chaperone JAB PF01398.16 ETO15101.1 - 0.28 10.9 3.5 1.4 8.7 2.3 2.4 1 1 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease zf-C3HC4_2 PF13923.1 ETO15102.1 - 0.011 15.8 3.2 0.047 13.7 2.2 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Papo_T_antigen PF02380.10 ETO15103.1 - 0.0031 17.4 6.8 0.0074 16.1 4.7 1.8 1 0 0 1 1 1 1 T-antigen specific domain DUF2130 PF09903.4 ETO15103.1 - 0.17 10.6 1.5 0.12 11.0 0.1 1.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) FmrO PF07091.6 ETO15104.1 - 0.045 12.7 0.4 0.049 12.6 0.3 1.1 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Mcp5_PH PF12814.2 ETO15105.1 - 3.9e-06 26.7 0.0 1.4e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Nucleoplasmin PF03066.10 ETO15105.1 - 0.00083 18.8 8.3 0.0022 17.5 5.7 1.7 1 0 0 1 1 1 1 Nucleoplasmin CDC45 PF02724.9 ETO15105.1 - 0.015 13.3 9.0 0.036 12.1 6.2 1.7 1 0 0 1 1 1 0 CDC45-like protein Anoctamin PF04547.7 ETO15106.1 - 1.1e-36 126.4 24.4 1.7e-34 119.2 16.9 2.2 1 1 0 1 1 1 1 Calcium-activated chloride channel Anoctamin PF04547.7 ETO15107.1 - 1.4e-35 122.8 4.1 1.7e-35 122.5 2.8 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel TMF_DNA_bd PF12329.3 ETO15109.1 - 0.00023 20.8 6.9 0.00023 20.8 4.8 4.4 4 0 0 4 4 4 1 TATA element modulatory factor 1 DNA binding CENP-Q PF13094.1 ETO15109.1 - 0.0013 18.7 10.0 0.0013 18.7 6.9 3.5 1 1 2 3 3 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Reo_sigmaC PF04582.7 ETO15109.1 - 0.0025 17.0 9.5 0.03 13.4 2.3 2.1 2 0 0 2 2 2 2 Reovirus sigma C capsid protein IncA PF04156.9 ETO15109.1 - 0.0049 16.4 40.2 0.099 12.2 10.3 2.5 2 1 0 2 2 2 2 IncA protein Prp19 PF08606.6 ETO15109.1 - 0.0088 15.7 0.5 0.0088 15.7 0.3 3.1 3 0 0 3 3 3 1 Prp19/Pso4-like ADIP PF11559.3 ETO15109.1 - 0.013 15.3 9.7 0.013 15.3 6.7 3.8 2 2 2 4 4 4 0 Afadin- and alpha -actinin-Binding HOOK PF05622.7 ETO15109.1 - 0.088 10.6 38.7 0.16 9.7 12.0 2.0 2 0 0 2 2 2 0 HOOK protein Vac_Fusion PF02346.11 ETO15109.1 - 0.21 11.0 14.1 1 8.8 0.0 4.9 3 2 2 5 5 5 0 Chordopoxvirus fusion protein Sec20 PF03908.8 ETO15109.1 - 0.55 9.9 14.0 0.17 11.6 2.1 3.8 2 1 2 4 4 4 0 Sec20 DUF869 PF05911.6 ETO15109.1 - 0.59 8.2 35.8 1.4 7.0 24.6 1.5 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) ATG16 PF08614.6 ETO15109.1 - 1 9.1 40.5 0.064 13.0 10.3 3.6 2 2 0 2 2 2 0 Autophagy protein 16 (ATG16) Phage_GP20 PF06810.6 ETO15109.1 - 3.8 6.9 36.5 0.94 8.9 4.9 3.3 2 1 0 3 3 3 0 Phage minor structural protein GP20 Pox_A_type_inc PF04508.7 ETO15109.1 - 4.2 7.4 12.6 6.2 6.8 0.2 4.1 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat AAA_13 PF13166.1 ETO15109.1 - 7.7 4.8 34.9 1.6e+03 -2.9 24.2 2.3 1 1 0 1 1 1 0 AAA domain DUF3584 PF12128.3 ETO15109.1 - 8.2 3.6 34.4 12 3.0 23.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) SlyX PF04102.7 ETO15109.1 - 8.8 6.7 25.1 1.2 9.5 1.1 5.3 3 1 2 5 5 5 0 SlyX PhoU PF01895.14 ETO15109.1 - 9.3 6.7 8.6 2.3 8.7 0.7 3.3 1 1 1 3 3 3 0 PhoU domain PhoU_div PF01865.11 ETO15110.1 - 0.021 14.0 0.3 0.032 13.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF47 CbiA PF01656.18 ETO15111.1 - 4.8e-24 84.8 0.1 6.4e-24 84.4 0.1 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 ETO15111.1 - 9.1e-15 54.4 0.0 1e-08 34.5 0.0 2.3 1 1 1 2 2 2 2 ATPase MipZ VirC1 PF07015.6 ETO15111.1 - 6.4e-13 48.3 0.2 9.2e-13 47.8 0.2 1.2 1 0 0 1 1 1 1 VirC1 protein AAA_31 PF13614.1 ETO15111.1 - 1.1e-07 31.9 0.0 0.00011 22.1 0.0 2.3 1 1 1 2 2 2 2 AAA domain ArsA_ATPase PF02374.10 ETO15111.1 - 2.5e-07 30.0 0.0 1.8e-06 27.2 0.0 2.1 1 1 1 2 2 2 1 Anion-transporting ATPase ArgK PF03308.11 ETO15111.1 - 0.00014 20.7 0.0 0.22 10.2 0.0 2.4 2 0 0 2 2 2 2 ArgK protein SRP54 PF00448.17 ETO15111.1 - 0.00023 20.6 0.2 0.00054 19.4 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain YhjQ PF06564.7 ETO15111.1 - 0.0079 15.5 0.0 1.9 7.7 0.0 2.2 1 1 1 2 2 2 2 YhjQ protein ParA PF10609.4 ETO15111.1 - 0.019 14.8 0.2 0.04 13.8 0.1 1.6 1 0 0 1 1 1 0 ParA/MinD ATPase like ATP_bind_1 PF03029.12 ETO15111.1 - 0.021 14.3 0.0 4.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Glyco_hydro_97 PF10566.4 ETO15111.1 - 0.063 12.3 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Glycoside hydrolase 97 AAA_24 PF13479.1 ETO15111.1 - 0.081 12.4 0.1 0.17 11.4 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 ETO15111.1 - 0.13 11.6 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF4094 PF13334.1 ETO15112.1 - 0.17 12.3 0.1 0.17 12.3 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) Surf_Ag_VNR PF07244.10 ETO15113.1 - 0.16 12.3 2.7 1.6 9.2 0.0 3.1 3 1 0 3 3 3 0 Surface antigen variable number repeat DUF4172 PF13776.1 ETO15113.1 - 0.18 11.9 3.4 10 6.2 0.1 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4172) DUF3782 PF12644.2 ETO15113.1 - 0.44 10.3 2.5 1.8 8.4 1.7 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) Herpes_U30 PF04523.8 ETO15114.1 - 0.0045 14.5 0.6 0.0051 14.3 0.4 1.0 1 0 0 1 1 1 1 Herpes virus tegument protein U30 FAM178 PF14816.1 ETO15114.1 - 0.057 12.1 0.3 0.078 11.6 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function, FAM178 MRP-63 PF14978.1 ETO15114.1 - 0.15 12.4 2.5 0.17 12.3 0.7 1.8 1 1 0 1 1 1 0 Mitochondrial ribosome protein 63 THP2 PF09432.5 ETO15115.1 - 0.012 15.4 1.0 0.055 13.3 0.7 2.2 1 1 0 1 1 1 0 Tho complex subunit THP2 RHD3 PF05879.7 ETO15116.1 - 0.00012 20.2 11.9 0.00016 19.8 0.0 2.5 1 1 2 3 3 3 1 Root hair defective 3 GTP-binding protein (RHD3) Cytochrom_B562 PF07361.6 ETO15116.1 - 0.00029 21.1 0.2 0.0008 19.7 0.1 1.7 1 0 0 1 1 1 1 Cytochrome b562 DUF1524 PF07510.6 ETO15116.1 - 0.039 13.7 0.6 0.088 12.6 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1524) DUF1539 PF07560.6 ETO15116.1 - 0.049 13.4 0.9 1.1 9.1 0.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) Dynamin_N PF00350.18 ETO15116.1 - 0.08 12.7 0.7 0.24 11.2 0.5 2.2 1 1 0 1 1 1 0 Dynamin family RPAP3_C PF13877.1 ETO15118.1 - 0.035 14.0 0.1 0.14 12.1 0.0 2.1 1 1 2 3 3 3 0 Potential Monad-binding region of RPAP3 Kinesin PF00225.18 ETO15119.1 - 2.1e-23 82.5 0.0 2.7e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain DUF3643 PF12356.3 ETO15119.1 - 0.035 13.4 0.3 0.053 12.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3643) AAA_22 PF13401.1 ETO15119.1 - 0.04 14.0 0.0 0.056 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Nucleoplasmin PF03066.10 ETO15119.1 - 0.049 13.1 6.6 0.058 12.9 4.6 1.3 1 1 0 1 1 1 0 Nucleoplasmin DUF4611 PF15387.1 ETO15119.1 - 0.053 13.6 3.4 0.092 12.8 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Sigma70_ner PF04546.8 ETO15119.1 - 0.077 12.5 3.3 0.11 12.1 2.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region AAA_10 PF12846.2 ETO15119.1 - 0.094 12.1 0.2 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain DUF2457 PF10446.4 ETO15119.1 - 0.12 11.0 6.2 0.14 10.8 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RXT2_N PF08595.6 ETO15119.1 - 0.14 11.9 2.4 0.21 11.3 1.7 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Dicty_REP PF05086.7 ETO15119.1 - 0.3 8.8 3.3 0.36 8.5 2.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Phosphoprotein PF00922.12 ETO15119.1 - 0.31 10.2 2.9 0.8 8.8 0.0 2.0 2 0 0 2 2 2 0 Vesiculovirus phosphoprotein PBP1_TM PF14812.1 ETO15119.1 - 0.55 10.5 9.1 1 9.7 6.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 ETO15119.1 - 0.64 10.2 8.0 1.2 9.3 5.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain vATP-synt_E PF01991.13 ETO15120.1 - 3.8e-29 101.3 18.6 3.8e-29 101.3 12.9 1.7 1 1 1 2 2 2 1 ATP synthase (E/31 kDa) subunit CD20 PF04103.10 ETO15121.1 - 0.046 13.6 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 CD20-like family WD40 PF00400.27 ETO15123.1 - 6.2e-16 57.6 1.7 1.1e-05 25.1 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat MIP-T3 PF10243.4 ETO15123.1 - 0.52 8.7 37.0 0.79 8.1 25.7 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CDC45 PF02724.9 ETO15123.1 - 3 5.7 21.6 4.2 5.2 15.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Mgr1 PF08602.5 ETO15123.1 - 3.4 6.6 14.2 6.4 5.6 9.8 1.4 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit DUF966 PF06136.8 ETO15124.1 - 4.3 6.6 30.9 5.5 6.3 21.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) eRF1_2 PF03464.10 ETO15125.1 - 0.025 14.9 0.1 0.046 14.0 0.1 1.4 1 0 0 1 1 1 0 eRF1 domain 2 COG6 PF06419.6 ETO15125.1 - 0.058 11.5 0.4 0.074 11.1 0.3 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 Myc_N PF01056.13 ETO15126.1 - 0.1 11.7 7.8 0.12 11.5 5.4 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Vfa1 PF08432.5 ETO15126.1 - 0.62 10.0 9.4 0.78 9.7 6.5 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 WD40 PF00400.27 ETO15128.1 - 2.5e-75 245.8 18.1 2.8e-12 45.9 0.1 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat PQQ_2 PF13360.1 ETO15128.1 - 4.5e-07 29.5 0.3 0.00038 19.9 0.1 3.3 2 1 0 2 2 2 2 PQQ-like domain eIF2A PF08662.6 ETO15128.1 - 7e-07 29.1 0.0 0.037 13.7 0.0 3.4 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A DPPIV_N PF00930.16 ETO15128.1 - 0.036 12.6 0.1 1.7 7.1 0.0 3.2 2 2 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Gmad1 PF10647.4 ETO15128.1 - 0.079 12.3 0.0 22 4.3 0.0 3.2 3 1 0 3 3 3 0 Lipoprotein LpqB beta-propeller domain PD40 PF07676.7 ETO15128.1 - 0.19 11.4 12.1 15 5.3 0.0 6.7 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 ETO15128.1 - 2.5 7.5 9.5 61 3.0 0.1 4.8 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature DsbD_2 PF13386.1 ETO15129.1 - 0.045 13.4 0.0 0.059 13.1 0.0 1.1 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region DUF912 PF06024.7 ETO15129.1 - 0.066 13.2 0.4 0.11 12.5 0.1 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3753 PF12575.3 ETO15131.1 - 6.6 6.6 12.5 0.079 12.7 0.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3753) MFS_1 PF07690.11 ETO15133.1 - 0.0035 16.1 6.4 0.0057 15.4 0.1 2.6 3 0 0 3 3 3 2 Major Facilitator Superfamily DUF3624 PF12292.3 ETO15134.1 - 1.1 9.6 5.0 2.4 8.6 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3624) Mob1_phocein PF03637.12 ETO15135.1 - 5.2e-67 224.8 2.8 4.9e-39 133.7 0.0 2.2 1 1 1 2 2 2 2 Mob1/phocein family LcrG PF07216.7 ETO15137.1 - 0.035 14.1 0.1 0.082 12.9 0.0 1.5 1 0 0 1 1 1 0 LcrG protein WD40 PF00400.27 ETO15138.1 - 3.4e-69 226.4 22.4 2.2e-11 43.1 1.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO15138.1 - 3.9e-11 41.7 8.4 0.033 12.3 0.0 5.5 1 1 3 5 5 5 5 Nucleoporin Nup120/160 SAB PF04382.8 ETO15138.1 - 0.0045 16.6 0.9 0.013 15.1 0.6 1.8 1 0 0 1 1 1 1 SAB domain Reo_sigmaC PF04582.7 ETO15138.1 - 0.026 13.6 2.9 0.046 12.8 2.0 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein WD40 PF00400.27 ETO15139.1 - 1.6e-46 154.5 32.5 1.6e-10 40.4 1.5 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO15139.1 - 8.2e-08 30.8 6.7 0.00065 17.9 0.4 4.1 3 2 1 4 4 4 4 Nucleoporin Nup120/160 WD40 PF00400.27 ETO15140.1 - 0.0034 17.2 0.1 0.12 12.3 0.0 2.6 3 0 0 3 3 3 1 WD domain, G-beta repeat ChlamPMP_M PF07548.6 ETO15140.1 - 0.082 12.6 0.1 0.1 12.3 0.1 1.1 1 0 0 1 1 1 0 Chlamydia polymorphic membrane protein middle domain LRS4 PF10422.4 ETO15141.1 - 0.07 12.4 1.1 0.072 12.4 0.8 1.2 1 1 0 1 1 1 0 Monopolin complex subunit LRS4 Histone PF00125.19 ETO15142.1 - 1.7e-26 92.1 0.1 2.2e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 ETO15142.1 - 8.9e-07 28.8 0.0 1.3e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YdfA_immunity PF12127.3 ETO15142.1 - 0.011 14.6 0.1 0.013 14.3 0.1 1.1 1 0 0 1 1 1 0 SigmaW regulon antibacterial LRR_6 PF13516.1 ETO15143.1 - 0.0014 18.4 1.8 13 6.2 0.1 4.1 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.2 ETO15143.1 - 0.0017 17.9 2.0 0.22 11.1 0.1 3.8 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETO15143.1 - 0.41 10.8 4.5 42 4.7 0.1 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_7 PF13504.1 ETO15143.1 - 2.4 8.7 6.9 25 5.6 0.0 4.7 5 0 0 5 5 5 0 Leucine rich repeat Ank_2 PF12796.2 ETO15145.1 - 1.4e-17 63.7 0.3 2.3e-10 40.6 0.1 3.0 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO15145.1 - 5.7e-15 55.3 1.2 1.2e-07 32.0 0.1 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 ETO15145.1 - 5.1e-09 35.5 0.8 2e-07 30.4 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 ETO15145.1 - 9.9e-09 35.1 2.7 4.4e-08 33.1 0.2 3.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO15145.1 - 1.3e-05 24.9 1.1 0.00015 21.6 0.0 3.4 4 0 0 4 4 4 1 Ankyrin repeat MerB PF03243.10 ETO15146.1 - 2e-05 24.4 0.1 2.6e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Alkylmercury lyase WD40 PF00400.27 ETO15147.1 - 1.5e-34 116.6 6.1 3.2e-11 42.6 0.0 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO15147.1 - 1.3e-07 30.1 0.2 0.003 15.7 0.0 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO15147.1 - 0.012 15.3 0.1 0.059 13.0 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Topoisom_bac PF01131.15 ETO15148.1 - 7.4e-86 288.4 0.6 3.5e-85 286.2 0.4 2.0 1 1 0 1 1 1 1 DNA topoisomerase Sre PF03125.13 ETO15148.1 - 0.24 10.2 1.9 3.2 6.6 0.1 2.4 2 0 0 2 2 2 0 C. elegans Sre G protein-coupled chemoreceptor DUF2763 PF10961.3 ETO15148.1 - 1.2 9.5 6.8 1.6 9.1 1.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) WD40 PF00400.27 ETO15150.1 - 5.9e-32 108.3 15.4 3.3e-11 42.6 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat PD40 PF07676.7 ETO15150.1 - 6.6e-10 38.4 4.3 0.56 9.9 0.0 6.0 6 0 0 6 6 6 3 WD40-like Beta Propeller Repeat eIF2A PF08662.6 ETO15150.1 - 0.00038 20.2 0.1 0.0052 16.5 0.0 2.6 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 ETO15150.1 - 0.00052 19.5 0.0 0.15 11.4 0.0 2.2 1 1 1 2 2 2 2 PQQ-like domain Nbas_N PF15492.1 ETO15150.1 - 0.0016 17.5 0.2 5.7 5.9 0.0 4.0 1 1 3 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 ETO15150.1 - 0.035 12.2 0.3 4 5.4 0.0 2.2 1 1 1 2 2 2 0 Nucleoporin Nup120/160 FAINT PF04385.10 ETO15150.1 - 0.038 13.8 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, DUF529 DUF1258 PF06869.7 ETO15150.1 - 0.054 12.5 1.5 1.4 7.9 0.0 2.7 2 1 2 4 4 4 0 Protein of unknown function (DUF1258) Proteasome_A_N PF10584.4 ETO15150.1 - 0.14 11.5 10.4 20 4.5 0.0 5.4 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Resistin PF06954.6 ETO15150.1 - 0.14 12.4 1.1 13 6.1 0.0 3.2 2 1 2 4 4 4 0 Resistin WD40 PF00400.27 ETO15151.1 - 8.3e-24 82.5 3.1 5.6e-09 35.5 0.2 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 ETO15151.1 - 1.7e-06 27.8 3.3 0.11 12.1 0.2 4.3 3 1 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO15151.1 - 2.2e-05 22.7 0.2 0.0025 16.0 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 ETO15151.1 - 5.7e-05 22.5 0.0 0.0066 15.9 0.0 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.6 ETO15151.1 - 0.0002 20.2 0.2 0.051 12.3 0.0 2.3 2 0 0 2 2 2 2 Nup133 N terminal like Fringe PF02434.11 ETO15152.1 - 0.0031 16.7 0.1 0.005 16.1 0.1 1.3 1 0 0 1 1 1 1 Fringe-like WND PF07861.6 ETO15152.1 - 0.28 10.1 0.5 0.45 9.4 0.4 1.2 1 0 0 1 1 1 0 WisP family N-Terminal Region SF-assemblin PF06705.6 ETO15153.1 - 0.012 14.8 2.4 0.024 13.8 1.6 1.4 1 0 0 1 1 1 0 SF-assemblin/beta giardin Geminin PF07412.7 ETO15154.1 - 0.035 13.7 0.0 0.076 12.6 0.0 1.5 1 0 0 1 1 1 0 Geminin Nic96 PF04097.9 ETO15155.1 - 3e-06 25.6 0.0 3.2e-06 25.5 0.0 1.0 1 0 0 1 1 1 1 Nup93/Nic96 Nic96 PF04097.9 ETO15156.1 - 3.1e-18 65.2 3.0 4.6e-18 64.6 2.1 1.3 1 1 0 1 1 1 1 Nup93/Nic96 CRISPR_assoc PF08798.6 ETO15156.1 - 0.033 13.9 0.2 0.07 12.8 0.2 1.5 1 0 0 1 1 1 0 CRISPR associated protein Kelch_6 PF13964.1 ETO15157.1 - 7.9e-07 28.9 5.6 0.03 14.5 0.2 5.1 7 0 0 7 7 7 2 Kelch motif Kelch_2 PF07646.10 ETO15157.1 - 8.8e-07 28.4 5.3 0.00013 21.5 0.1 4.2 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 ETO15157.1 - 4.9e-06 26.3 0.5 1.2 9.2 0.0 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO15157.1 - 0.00047 19.8 0.1 3.8 7.3 0.0 4.2 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO15157.1 - 0.0034 16.8 4.2 0.12 11.9 0.4 4.3 5 0 0 5 5 5 1 Kelch motif TPR_12 PF13424.1 ETO15158.1 - 7.7e-28 96.2 6.1 3.8e-17 61.9 0.7 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO15158.1 - 1.5e-10 40.5 16.5 6e-05 22.6 2.9 3.5 2 1 1 3 3 3 3 TPR repeat TPR_10 PF13374.1 ETO15158.1 - 1.3e-09 37.6 0.0 0.016 15.0 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO15158.1 - 1.1e-08 34.2 3.7 0.0079 15.9 0.0 4.8 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO15158.1 - 2.7e-07 29.8 30.0 0.0006 19.4 1.5 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO15158.1 - 8.9e-07 28.2 24.8 3.2e-06 26.5 0.4 4.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO15158.1 - 3.6e-06 26.4 18.1 0.014 15.2 0.3 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO15158.1 - 0.0089 16.1 3.1 4.9 7.6 0.1 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO15158.1 - 0.34 11.4 4.6 15 6.3 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 ETO15158.1 - 0.91 9.4 9.3 0.76 9.7 0.1 3.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Syntaxin PF00804.20 ETO15159.1 - 0.0013 18.9 6.4 0.26 11.4 3.3 2.4 2 1 0 2 2 2 2 Syntaxin CorA PF01544.13 ETO15159.1 - 0.027 13.5 1.5 0.031 13.3 1.1 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4319 PF14203.1 ETO15159.1 - 0.041 13.4 1.7 6.4 6.4 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4319) Mating_N PF12731.2 ETO15159.1 - 0.08 12.8 0.3 0.57 10.0 0.0 2.1 1 1 0 2 2 2 0 Mating-type protein beta 1 BamHI PF02923.10 ETO15159.1 - 0.081 12.8 3.4 0.099 12.5 2.4 1.1 1 0 0 1 1 1 0 Restriction endonuclease BamHI DUF2063 PF09836.4 ETO15159.1 - 0.086 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2063) IncA PF04156.9 ETO15159.1 - 0.1 12.1 1.1 0.13 11.8 0.8 1.2 1 0 0 1 1 1 0 IncA protein Cauli_DNA-bind PF03310.8 ETO15159.1 - 0.23 11.3 6.4 6.8 6.5 0.0 2.1 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein DUF948 PF06103.6 ETO15159.1 - 0.67 9.8 5.9 5.7 6.8 3.1 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.7 ETO15159.1 - 1.3 8.7 6.8 0.85 9.4 3.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.6 ETO15159.1 - 6.8 6.6 10.9 18 5.3 1.3 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) NACHT PF05729.7 ETO15160.1 - 5.4e-08 32.6 0.0 1.2e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain DUF4014 PF13198.1 ETO15160.1 - 0.021 15.2 0.6 0.13 12.7 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) FYVE PF01363.16 ETO15161.1 - 1.9e-08 34.0 4.0 4.2e-08 32.9 2.8 1.6 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 ETO15161.1 - 1.9e-05 24.8 0.0 4.2e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 PH domain BAF1_ABF1 PF04684.8 ETO15161.1 - 0.84 8.4 12.8 1.2 7.8 8.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SelP_N PF04592.9 ETO15161.1 - 2 7.7 13.7 3.6 6.9 9.5 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SAM_1 PF00536.25 ETO15162.1 - 3.9e-15 55.7 0.7 6.3e-15 55.1 0.5 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO15162.1 - 3e-08 33.3 0.5 4.9e-08 32.6 0.3 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Shisa PF13908.1 ETO15162.1 - 0.00091 19.4 1.6 0.0012 19.0 1.1 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator SID-1_RNA_chan PF13965.1 ETO15162.1 - 0.0095 14.1 0.4 0.01 14.0 0.3 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Peptidase_S49_N PF08496.5 ETO15162.1 - 0.07 12.9 0.3 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Tenui_PVC2 PF06656.6 ETO15162.1 - 0.25 9.0 3.4 0.32 8.7 2.4 1.2 1 0 0 1 1 1 0 Tenuivirus PVC2 protein SHP PF03579.8 ETO15162.1 - 0.25 10.7 8.4 0.42 9.9 5.8 1.3 1 0 0 1 1 1 0 Small hydrophobic protein TMEM154 PF15102.1 ETO15162.1 - 0.27 10.9 6.5 0.37 10.4 4.5 1.3 1 0 0 1 1 1 0 TMEM154 protein family Chordopox_A33R PF05966.7 ETO15162.1 - 0.4 9.4 2.5 0.51 9.0 1.8 1.2 1 0 0 1 1 1 0 Chordopoxvirus A33R protein NTP_transf_2 PF01909.18 ETO15163.1 - 0.00025 21.2 0.3 0.0011 19.2 0.0 2.2 2 1 0 2 2 2 1 Nucleotidyltransferase domain zf-trcl PF13451.1 ETO15165.1 - 0.032 13.8 0.5 0.071 12.7 0.1 1.8 2 0 0 2 2 2 0 Probable zinc-binding domain ROF PF07073.7 ETO15166.1 - 0.08 12.9 0.2 0.16 12.0 0.1 1.8 1 1 0 1 1 1 0 Modulator of Rho-dependent transcription termination (ROF) HC2 PF07382.6 ETO15167.1 - 0.0013 18.6 9.1 0.0016 18.2 6.3 1.2 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 DPCD PF14913.1 ETO15167.1 - 0.08 12.0 0.2 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 DPCD protein family Leukemia_assc_2 PF15197.1 ETO15168.1 - 0.55 9.9 3.9 1.4 8.6 0.4 2.3 1 1 1 2 2 2 0 Leukemia-associated protein 2 EpoR_lig-bind PF09067.5 ETO15169.1 - 0.0044 16.9 0.8 0.0082 16.1 0.6 1.5 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding FAM176 PF14851.1 ETO15170.1 - 1.2 8.7 4.2 1.4 8.5 2.9 1.1 1 0 0 1 1 1 0 FAM176 family Ank_2 PF12796.2 ETO15172.1 - 8.1e-07 29.2 1.9 0.0022 18.2 0.1 3.6 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO15172.1 - 0.00058 20.0 0.2 0.0054 16.9 0.0 2.7 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.25 ETO15172.1 - 0.0031 17.2 0.0 0.047 13.5 0.0 2.9 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.1 ETO15172.1 - 0.0069 16.5 0.5 1.5 9.3 0.0 3.6 4 0 0 4 4 4 1 Ankyrin repeat DNA_pol_E_B PF04042.11 ETO15172.1 - 0.0073 15.5 0.4 0.1 11.8 0.0 2.4 2 1 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Vif PF00559.12 ETO15172.1 - 0.012 15.5 1.4 2.6 7.8 0.2 2.2 2 0 0 2 2 2 0 Retroviral Vif (Viral infectivity) protein Ank_4 PF13637.1 ETO15172.1 - 0.014 15.8 1.1 9.4 6.8 0.0 3.3 2 1 1 3 3 3 0 Ankyrin repeats (many copies) NUFIP1 PF10453.4 ETO15172.1 - 0.86 9.1 6.1 0.39 10.2 0.4 2.5 2 0 0 2 2 2 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) DUF1430 PF07242.6 ETO15174.1 - 0.00062 19.7 3.9 0.49 10.4 0.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1430) DUF1510 PF07423.6 ETO15174.1 - 0.0027 17.1 3.4 0.0042 16.4 2.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Peptidase_S49_N PF08496.5 ETO15174.1 - 0.042 13.6 3.7 0.077 12.7 2.6 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Pex14_N PF04695.8 ETO15175.1 - 0.018 15.0 3.1 0.025 14.6 2.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CWC25 PF12542.3 ETO15175.1 - 0.036 14.4 0.9 0.048 14.1 0.6 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor CYSTM PF12734.2 ETO15175.1 - 0.94 9.6 4.1 1.9 8.5 2.9 1.5 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance DUF2431 PF10354.4 ETO15176.1 - 5e-09 36.3 1.5 4.4e-08 33.2 1.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) DUF4200 PF13863.1 ETO15178.1 - 0.0019 18.1 27.9 0.0019 18.1 19.4 4.1 3 1 1 4 4 4 2 Domain of unknown function (DUF4200) ERM PF00769.14 ETO15178.1 - 0.27 10.7 44.4 0.056 12.9 23.1 2.3 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF3259 PF11652.3 ETO15178.1 - 0.51 10.5 0.0 0.51 10.5 0.0 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3259) SDH_alpha PF03313.10 ETO15178.1 - 6.1 5.7 5.6 11 4.9 3.7 1.6 1 1 0 1 1 1 0 Serine dehydratase alpha chain Mit_ribos_Mrp51 PF11709.3 ETO15179.1 - 0.018 14.2 6.6 0.022 13.9 4.6 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit DUF445 PF04286.7 ETO15179.1 - 0.048 13.1 2.2 0.06 12.8 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF1217 PF06748.7 ETO15179.1 - 0.053 13.5 0.1 0.084 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1217) IncA PF04156.9 ETO15179.1 - 1.8 8.1 9.6 2.8 7.4 6.7 1.3 1 0 0 1 1 1 0 IncA protein DUF4404 PF14357.1 ETO15179.1 - 2.2 8.7 7.3 6.1 7.3 0.3 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4404) DUF3972 PF13118.1 ETO15180.1 - 0.016 15.2 1.6 0.016 15.2 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) EphA2_TM PF14575.1 ETO15180.1 - 0.29 11.5 1.2 47 4.4 0.0 3.7 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF641 PF04859.7 ETO15180.1 - 2 8.2 8.6 2.2 8.0 1.1 2.6 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Claudin_2 PF13903.1 ETO15180.1 - 6.7 6.3 10.9 1.1 8.8 1.5 2.9 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Cortex-I_coil PF09304.5 ETO15180.1 - 8.4 6.4 16.5 3 7.9 4.6 2.5 2 0 0 2 2 2 0 Cortexillin I, coiled coil MMR_HSR1 PF01926.18 ETO15181.1 - 1.9e-10 40.7 0.0 3e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETO15181.1 - 0.00044 19.5 0.0 0.00083 18.6 0.0 1.5 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 ETO15181.1 - 0.00051 19.9 0.1 0.0012 18.6 0.0 1.6 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 ETO15181.1 - 0.0083 16.6 0.0 0.014 15.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 ETO15181.1 - 0.016 14.3 0.1 0.026 13.6 0.0 1.4 2 0 0 2 2 2 0 AIG1 family ABC_tran PF00005.22 ETO15181.1 - 0.042 14.1 0.1 0.076 13.3 0.0 1.5 1 1 0 1 1 1 0 ABC transporter DUF258 PF03193.11 ETO15181.1 - 0.053 12.7 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_21 PF13304.1 ETO15181.1 - 0.072 13.0 0.0 0.096 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain RicinB_lectin_2 PF14200.1 ETO15182.1 - 0.031 14.6 0.2 0.21 11.9 0.0 2.1 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like IL1 PF00340.14 ETO15182.1 - 0.045 13.2 0.0 0.21 11.0 0.0 2.0 2 1 0 2 2 2 0 Interleukin-1 / 18 FGF PF00167.13 ETO15182.1 - 0.048 13.4 0.0 0.45 10.2 0.0 2.0 2 0 0 2 2 2 0 Fibroblast growth factor Vps5 PF09325.5 ETO15184.1 - 0.16 11.1 1.5 0.21 10.8 1.0 1.1 1 0 0 1 1 1 0 Vps5 C terminal like DUF1664 PF07889.7 ETO15184.1 - 0.19 11.4 0.8 0.75 9.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Peptidase_C97 PF05903.9 ETO15187.1 - 0.00036 20.3 0.6 0.00074 19.3 0.1 1.8 2 0 0 2 2 2 1 PPPDE putative peptidase domain LRAT PF04970.8 ETO15187.1 - 0.0055 16.6 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Lecithin retinol acyltransferase RCC1 PF00415.13 ETO15188.1 - 7.7e-40 134.8 28.5 2.8e-07 30.6 0.1 9.4 8 1 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat RabGAP-TBC PF00566.13 ETO15188.1 - 8.3e-38 130.0 8.5 8.3e-38 130.0 5.9 5.2 4 1 0 4 4 4 1 Rab-GTPase-TBC domain RCC1_2 PF13540.1 ETO15188.1 - 9.7e-18 63.2 36.1 1.4e-07 30.9 3.2 6.0 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat EMP24_GP25L PF01105.19 ETO15189.1 - 9.1e-34 116.7 0.1 1.8e-33 115.7 0.1 1.5 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD NPV_P10 PF05531.7 ETO15190.1 - 0.0078 16.4 15.8 1.9 8.8 0.4 3.5 2 1 1 3 3 3 3 Nucleopolyhedrovirus P10 protein Cep57_CLD_2 PF14197.1 ETO15190.1 - 0.014 15.3 9.0 0.014 15.3 6.2 3.4 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 Herpes_BLRF2 PF05812.7 ETO15190.1 - 0.014 15.1 9.3 0.73 9.6 0.4 2.4 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein CP12 PF02672.10 ETO15190.1 - 0.041 14.3 3.3 0.12 12.8 0.3 2.5 2 0 0 2 2 2 0 CP12 domain RraB PF06877.6 ETO15190.1 - 0.11 13.2 4.9 0.55 10.9 0.3 2.6 1 1 0 2 2 2 0 Regulator of ribonuclease activity B AAA_13 PF13166.1 ETO15190.1 - 0.12 10.7 21.0 0.17 10.3 14.6 1.1 1 0 0 1 1 1 0 AAA domain L31 PF09784.4 ETO15190.1 - 0.14 12.2 8.1 0.061 13.3 0.7 2.6 1 1 2 3 3 3 0 Mitochondrial ribosomal protein L31 DivIC PF04977.10 ETO15190.1 - 0.17 11.4 18.7 0.62 9.5 0.7 3.6 1 1 2 3 3 3 0 Septum formation initiator Atg14 PF10186.4 ETO15190.1 - 0.36 9.7 24.4 0.029 13.3 10.8 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3450 PF11932.3 ETO15190.1 - 0.38 9.9 18.0 1.3 8.2 6.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Sipho_Gp157 PF05565.6 ETO15190.1 - 0.39 10.2 9.5 0.04 13.4 1.9 2.5 2 1 0 2 2 2 0 Siphovirus Gp157 HALZ PF02183.13 ETO15190.1 - 0.56 9.9 12.8 2 8.2 1.1 4.2 3 2 1 4 4 4 0 Homeobox associated leucine zipper HrpB7 PF09486.5 ETO15190.1 - 0.57 10.1 7.4 1.1 9.1 0.1 2.6 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Reo_sigmaC PF04582.7 ETO15190.1 - 0.85 8.7 12.3 0.27 10.3 2.8 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Spc42p PF11544.3 ETO15190.1 - 1.1 9.2 13.8 0.17 11.7 4.8 2.9 2 1 1 3 3 3 0 Spindle pole body component Spc42p DUF4200 PF13863.1 ETO15190.1 - 1.2 9.1 22.9 0.17 11.8 7.5 2.8 2 1 0 3 3 3 0 Domain of unknown function (DUF4200) Spc7 PF08317.6 ETO15190.1 - 2.9 6.4 25.7 0.52 8.9 7.2 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4140 PF13600.1 ETO15190.1 - 3.4 8.1 11.2 2.6 8.5 0.6 3.1 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) ATG16 PF08614.6 ETO15190.1 - 3.5 7.3 24.1 5.3 6.8 10.4 2.7 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) bZIP_1 PF00170.16 ETO15190.1 - 3.6 7.6 16.9 0.38 10.7 0.7 3.7 2 1 1 3 3 3 0 bZIP transcription factor Glycohydro_20b2 PF14845.1 ETO15190.1 - 4.4 7.9 9.6 3.6 8.2 4.1 2.1 1 1 1 2 2 2 0 beta-acetyl hexosaminidase like UCH PF00443.24 ETO15190.1 - 5.1 6.1 12.9 7.5 5.5 8.9 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF2664 PF10867.3 ETO15190.1 - 5.3 7.7 8.8 4.2 8.0 1.8 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2664) FlaC_arch PF05377.6 ETO15190.1 - 5.4 6.9 15.1 1.6 8.7 0.1 4.5 3 2 1 4 4 3 0 Flagella accessory protein C (FlaC) IncA PF04156.9 ETO15190.1 - 5.4 6.5 30.7 2.9e+03 -2.4 21.2 2.9 1 1 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 ETO15190.1 - 8.9 6.2 22.3 1.1 9.1 6.1 3.4 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Myc_N PF01056.13 ETO15191.1 - 0.0068 15.6 8.5 0.0079 15.4 5.9 1.0 1 0 0 1 1 1 1 Myc amino-terminal region DUF1510 PF07423.6 ETO15191.1 - 0.14 11.5 20.3 0.15 11.3 14.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) N-SET PF11764.3 ETO15191.1 - 0.23 11.3 12.8 0.27 11.1 8.8 1.1 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N VID27 PF08553.5 ETO15191.1 - 0.29 9.3 8.7 0.31 9.2 6.1 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein RR_TM4-6 PF06459.7 ETO15191.1 - 0.54 10.0 19.6 0.62 9.9 13.6 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_S30 PF01577.11 ETO15191.1 - 0.96 8.7 13.5 1.3 8.4 9.3 1.1 1 0 0 1 1 1 0 Potyvirus P1 protease Spore_coat_CotO PF14153.1 ETO15191.1 - 1 8.7 18.1 1.1 8.6 12.6 1.0 1 0 0 1 1 1 0 Spore coat protein CotO DUF4557 PF15101.1 ETO15191.1 - 1.1 9.0 8.3 1.3 8.8 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) ORC6 PF05460.8 ETO15191.1 - 1.2 8.1 17.1 1.3 8.0 11.9 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Zip PF02535.17 ETO15191.1 - 1.7 7.5 4.7 1.8 7.5 3.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Sporozoite_P67 PF05642.6 ETO15191.1 - 2 6.2 10.7 2.3 5.9 7.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Afi1 PF07792.7 ETO15191.1 - 2 8.4 8.0 2.3 8.2 5.5 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2052 PF09747.4 ETO15191.1 - 2.2 8.1 12.3 2.5 7.9 8.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RP-C_C PF11800.3 ETO15191.1 - 2.2 7.9 7.3 2.5 7.7 5.1 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region GAGA_bind PF06217.7 ETO15191.1 - 2.4 8.0 13.9 3 7.7 9.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Tim54 PF11711.3 ETO15191.1 - 2.5 6.6 13.4 2.8 6.4 9.3 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.9 ETO15191.1 - 2.9 5.8 10.9 3 5.7 7.5 1.0 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.1 ETO15191.1 - 3.2 7.4 12.1 4.3 7.0 8.4 1.1 1 0 0 1 1 1 0 FAM176 family DUF4530 PF15039.1 ETO15191.1 - 3.2 7.6 7.0 4.5 7.2 4.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) Nucleoside_tran PF01733.13 ETO15191.1 - 3.3 6.7 4.8 3.8 6.5 3.3 1.1 1 0 0 1 1 1 0 Nucleoside transporter Asp-B-Hydro_N PF05279.6 ETO15191.1 - 3.6 7.3 15.0 4.2 7.1 10.4 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Effector_1 PF04518.7 ETO15191.1 - 3.9 6.3 9.3 4.2 6.2 6.5 1.0 1 0 0 1 1 1 0 Effector from type III secretion system NPR3 PF03666.8 ETO15191.1 - 5.2 5.4 14.3 5.7 5.3 9.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Cytomega_UL84 PF06284.6 ETO15191.1 - 5.2 5.3 5.6 6 5.1 3.9 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein TLP-20 PF06088.6 ETO15191.1 - 5.5 6.6 10.6 6.3 6.4 7.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PRP38_assoc PF12871.2 ETO15191.1 - 6.3 7.4 11.5 3 8.4 6.5 1.5 1 1 1 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Calc_CGRP_IAPP PF00214.14 ETO15191.1 - 6.5 6.7 7.2 8.2 6.4 5.0 1.2 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family AUX_IAA PF02309.11 ETO15191.1 - 6.6 6.4 13.0 7.4 6.2 9.0 1.0 1 0 0 1 1 1 0 AUX/IAA family RRN3 PF05327.6 ETO15191.1 - 7 4.6 7.7 7.5 4.5 5.4 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DHHW PF14286.1 ETO15191.1 - 7.3 5.7 9.2 8.4 5.5 6.4 1.1 1 0 0 1 1 1 0 DHHW protein Ycf1 PF05758.7 ETO15191.1 - 7.8 4.0 13.9 8.4 3.9 9.7 1.0 1 0 0 1 1 1 0 Ycf1 DUF913 PF06025.7 ETO15191.1 - 8.3 5.0 9.2 9 4.9 6.4 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NARP1 PF12569.3 ETO15191.1 - 9 4.9 18.1 10 4.7 12.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Sec62 PF03839.11 ETO15191.1 - 9.9 5.5 17.0 13 5.1 11.8 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Menin PF05053.8 ETO15192.1 - 1 7.4 26.0 0.075 11.1 5.7 2.1 2 0 0 2 2 2 0 Menin WD40 PF00400.27 ETO15193.1 - 4.5e-75 245.0 14.4 1.3e-13 50.2 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO15193.1 - 1.8e-08 32.9 7.7 0.0073 14.4 0.1 4.4 1 1 2 4 4 4 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO15193.1 - 5.4e-07 29.3 2.5 0.00069 19.1 0.3 2.3 1 1 1 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 ETO15193.1 - 2.2e-06 26.7 9.0 1 8.0 0.3 4.8 1 1 3 4 4 4 4 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO15193.1 - 4.4e-05 21.9 2.8 0.94 7.6 0.0 3.3 1 1 1 3 3 3 3 Cytochrome D1 heme domain DPPIV_N PF00930.16 ETO15193.1 - 0.00033 19.3 0.5 0.088 11.3 0.0 3.0 3 0 0 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Gmad1 PF10647.4 ETO15193.1 - 0.00048 19.5 0.0 2.5 7.4 0.0 3.7 2 1 1 3 3 3 1 Lipoprotein LpqB beta-propeller domain PD40 PF07676.7 ETO15193.1 - 0.0015 18.1 6.6 4.4 7.0 0.1 5.7 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat IKI3 PF04762.7 ETO15193.1 - 0.017 12.9 0.0 0.05 11.4 0.0 1.9 1 1 1 2 2 2 0 IKI3 family Proteasome_A_N PF10584.4 ETO15193.1 - 0.018 14.3 6.6 1.2 8.4 0.1 4.6 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Hira PF07569.6 ETO15193.1 - 0.059 12.5 4.2 5 6.2 0.0 3.6 1 1 3 4 4 4 0 TUP1-like enhancer of split TruB_C PF09142.6 ETO15193.1 - 0.081 12.5 0.0 2 8.1 0.0 2.7 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal ubiquitin PF00240.18 ETO15194.1 - 1.5e-68 226.1 6.1 9.6e-34 114.6 0.4 2.2 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 ETO15194.1 - 1.9e-40 136.4 4.4 2.5e-20 71.9 0.4 2.2 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 ETO15194.1 - 1.4e-13 50.8 1.2 3.3e-05 24.0 0.1 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain Telomere_Sde2 PF13019.1 ETO15194.1 - 2.7e-08 33.6 0.0 0.0024 17.5 0.0 2.3 2 0 0 2 2 2 2 Telomere stability and silencing Rad60-SLD_2 PF13881.1 ETO15194.1 - 1.2e-07 31.6 0.3 0.021 14.6 0.0 2.7 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 ETO15194.1 - 4.2e-06 26.8 0.1 0.12 12.5 0.0 2.3 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 ETO15194.1 - 1.2e-05 25.1 0.6 0.17 11.8 0.0 2.3 2 0 0 2 2 2 2 GLUT4 regulating protein TUG DUF2870 PF11069.3 ETO15194.1 - 0.00013 21.9 0.0 1 9.4 0.0 2.9 2 2 0 2 2 2 2 Protein of unknown function (DUF2870) USP7_C2 PF14533.1 ETO15194.1 - 0.00022 20.7 0.2 0.58 9.5 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-specific protease C-terminal eRF1_1 PF03463.10 ETO15194.1 - 0.0014 18.1 1.0 1 8.9 0.0 3.4 2 1 2 4 4 4 1 eRF1 domain 1 PI3K_rbd PF00794.13 ETO15194.1 - 0.009 15.9 0.2 2.7 7.9 0.0 2.7 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain FlgD_ig PF13860.1 ETO15194.1 - 0.013 15.1 0.3 6.1 6.6 0.0 2.3 2 0 0 2 2 2 0 FlgD Ig-like domain GABP-alpha PF11620.3 ETO15194.1 - 0.054 13.4 0.2 13 5.8 0.0 2.2 2 0 0 2 2 2 0 GA-binding protein alpha chain DUF4131 PF13567.1 ETO15194.1 - 0.058 12.8 0.1 0.12 11.8 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) zf-RING_4 PF14570.1 ETO15194.1 - 0.083 12.4 0.7 0.15 11.6 0.5 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CTDII PF01556.13 ETO15194.1 - 0.18 11.6 4.2 2.9 7.8 0.2 2.3 1 1 1 2 2 2 0 DnaJ C terminal domain FERM_N PF09379.5 ETO15194.1 - 0.38 10.8 5.7 14 5.8 0.1 3.8 3 2 0 3 3 3 0 FERM N-terminal domain TauE PF01925.14 ETO15195.1 - 1e-20 74.2 30.2 2.7e-11 43.3 10.6 2.5 2 1 0 2 2 2 2 Sulfite exporter TauE/SafE RNA_pol_Rpb1_4 PF05000.12 ETO15195.1 - 0.082 12.6 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 4 Glyco_hydro_2 PF00703.16 ETO15196.1 - 2.2e-08 34.4 0.0 3.8e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 ETO15196.1 - 0.00025 20.0 0.1 0.00087 18.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain DUF1966 PF09260.6 ETO15197.1 - 0.048 13.7 0.4 5.2 7.2 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1966) Peptidase_M15_3 PF08291.6 ETO15200.1 - 6.4e-07 29.1 0.0 1.2e-06 28.2 0.0 1.5 1 1 0 1 1 1 1 Peptidase M15 CutA1 PF03091.10 ETO15201.1 - 0.046 13.3 1.0 0.087 12.4 0.7 1.6 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein Thioredoxin_8 PF13905.1 ETO15201.1 - 0.087 12.9 3.8 0.15 12.1 2.6 1.5 1 0 0 1 1 1 0 Thioredoxin-like Menin PF05053.8 ETO15202.1 - 4.1 5.4 11.2 7.5 4.5 7.7 1.4 1 0 0 1 1 1 0 Menin Radical_SAM PF04055.16 ETO15203.1 - 4.7e-08 33.3 0.0 8e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily CbiX PF01903.12 ETO15203.1 - 0.041 14.0 0.0 0.059 13.4 0.0 1.3 1 0 0 1 1 1 0 CbiX WD40 PF00400.27 ETO15205.1 - 6.6e-38 127.2 6.8 6.3e-11 41.7 0.3 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Kelch_5 PF13854.1 ETO15205.1 - 1.3e-07 31.4 1.2 0.039 13.9 0.0 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETO15205.1 - 6.2e-05 22.6 0.5 0.2 11.4 0.1 3.8 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO15205.1 - 0.00055 19.9 5.6 0.24 11.6 0.1 4.3 3 1 1 4 4 4 2 Kelch motif Cytochrom_D1 PF02239.11 ETO15205.1 - 0.0012 17.2 0.2 0.88 7.7 0.0 3.2 2 1 1 3 3 3 2 Cytochrome D1 heme domain Kelch_1 PF01344.20 ETO15205.1 - 0.0013 18.2 0.1 2.8 7.5 0.1 3.3 3 0 0 3 3 3 2 Kelch motif Nup160 PF11715.3 ETO15205.1 - 0.0088 14.2 0.1 1.3 7.0 0.0 2.6 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 ETO15205.1 - 0.016 14.3 0.4 0.082 11.9 0.1 2.1 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Kelch_3 PF13415.1 ETO15205.1 - 0.054 13.6 0.0 47 4.3 0.0 3.6 3 0 0 3 3 3 0 Galactose oxidase, central domain Peptidase_C1 PF00112.18 ETO15206.1 - 1.7e-55 188.2 5.2 1.9e-55 188.1 3.6 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 ETO15206.1 - 0.00054 18.6 0.2 0.00074 18.1 0.1 1.1 1 0 0 1 1 1 1 Peptidase C1-like family MTHFR_C PF12225.3 ETO15206.1 - 0.12 11.9 3.1 1.5 8.3 0.2 2.5 2 0 0 2 2 2 0 Methylene-tetrahydrofolate reductase C terminal PC4 PF02229.11 ETO15208.1 - 0.019 14.1 0.4 0.035 13.3 0.3 1.4 1 0 0 1 1 1 0 Transcriptional Coactivator p15 (PC4) DDE_Tnp_1_2 PF13586.1 ETO15208.1 - 0.024 14.7 0.1 0.04 14.1 0.1 1.4 1 0 0 1 1 1 0 Transposase DDE domain Tub PF01167.13 ETO15209.1 - 1.8e-35 122.1 0.3 1.8e-35 122.1 0.2 1.7 2 1 0 2 2 2 1 Tub family DUF3641 PF12345.3 ETO15209.1 - 0.54 10.0 3.9 0.2 11.5 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3641) zf-CCCH PF00642.19 ETO15210.1 - 1.6e-09 37.1 0.9 1.6e-09 37.1 0.6 1.7 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HAND PF09110.6 ETO15210.1 - 0.011 16.0 0.5 0.018 15.4 0.3 1.5 1 1 0 1 1 1 0 HAND PAD_M PF08527.5 ETO15211.1 - 0.032 13.6 0.2 0.16 11.3 0.0 2.0 1 1 2 3 3 3 0 Protein-arginine deiminase (PAD) middle domain CorA PF01544.13 ETO15211.1 - 0.078 12.0 2.0 0.099 11.6 1.4 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Helicase_C PF00271.26 ETO15211.1 - 0.1 12.5 0.2 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain TarH PF02203.10 ETO15211.1 - 0.13 12.0 0.8 0.24 11.2 0.3 1.5 1 1 1 2 2 2 0 Tar ligand binding domain homologue GWT1 PF06423.7 ETO15212.1 - 0.37 10.8 6.1 0.31 11.1 1.8 2.6 2 1 0 2 2 2 0 GWT1 DUF2663 PF10864.3 ETO15212.1 - 1.6 8.9 5.8 0.82 9.8 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2663) DEP PF00610.16 ETO15213.1 - 1.2e-06 28.1 2.0 6e-06 25.9 0.3 2.5 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DASH_Dad3 PF08656.5 ETO15213.1 - 0.013 15.1 0.6 0.048 13.3 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 IstB_IS21 PF01695.12 ETO15215.1 - 0.0032 16.9 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein Hormone_6 PF00236.13 ETO15215.1 - 0.052 13.3 0.2 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 Glycoprotein hormone Vasohibin PF14822.1 ETO15215.1 - 0.054 12.5 0.2 0.065 12.3 0.1 1.1 1 0 0 1 1 1 0 Vasohibin Nckap1 PF09735.4 ETO15216.1 - 2.3e-20 71.7 1.8 2.8e-20 71.5 1.2 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein Nckap1 PF09735.4 ETO15217.1 - 3e-47 160.8 0.0 1.5e-35 122.1 0.0 3.2 1 1 1 2 2 2 2 Membrane-associated apoptosis protein DUF2410 PF10307.4 ETO15217.1 - 0.026 13.8 0.2 0.048 13.0 0.2 1.4 1 0 0 1 1 1 0 Hypothetical protein (DUF2410) U-box PF04564.10 ETO15218.1 - 4.9e-12 45.6 0.1 1.4e-11 44.1 0.1 1.7 1 1 0 1 1 1 1 U-box domain zf-Nse PF11789.3 ETO15218.1 - 0.086 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF4501 PF14946.1 ETO15219.1 - 0.08 12.4 0.1 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) Kelch_1 PF01344.20 ETO15220.1 - 4e-06 26.2 1.9 0.001 18.5 0.0 3.6 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 ETO15220.1 - 5.7e-06 26.2 0.7 0.037 14.2 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 ETO15220.1 - 0.042 13.8 0.0 0.84 9.6 0.0 2.9 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.10 ETO15220.1 - 0.042 13.6 0.0 0.042 13.6 0.0 2.7 4 0 0 4 4 4 0 Kelch motif WD40 PF00400.27 ETO15221.1 - 1.8e-50 167.0 10.7 3.8e-12 45.5 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO15221.1 - 5.6e-10 37.9 6.0 0.015 13.4 0.0 5.6 1 1 4 5 5 5 5 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO15221.1 - 7e-09 35.6 1.7 0.01 15.5 0.0 3.4 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO15221.1 - 1.9e-05 23.1 1.8 0.017 13.4 0.1 2.9 1 1 2 3 3 3 3 Cytochrome D1 heme domain PD40 PF07676.7 ETO15221.1 - 0.0015 18.1 0.3 2.5 7.8 0.0 3.8 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO15221.1 - 0.014 15.6 0.1 28 5.0 0.0 3.7 2 2 2 4 4 4 0 Resistin B_lectin PF01453.19 ETO15221.1 - 0.015 15.2 5.4 0.019 14.8 0.1 2.9 1 1 2 3 3 3 0 D-mannose binding lectin Saf-Nte_pilin PF09460.5 ETO15221.1 - 0.052 13.3 1.9 0.16 11.7 1.3 1.9 1 1 0 1 1 1 0 Saf-pilin pilus formation protein C1-set PF07654.10 ETO15221.1 - 0.13 12.3 0.0 0.46 10.5 0.0 2.0 2 0 0 2 2 2 0 Immunoglobulin C1-set domain PigN PF04987.9 ETO15222.1 - 0.5 8.9 3.2 0.17 10.4 0.3 1.5 2 0 0 2 2 2 0 Phosphatidylinositolglycan class N (PIG-N) Cobl PF09469.5 ETO15222.1 - 0.9 9.5 8.5 0.53 10.2 2.1 2.1 2 0 0 2 2 2 0 Cordon-bleu ubiquitin-like domain Peptidase_U4 PF03419.8 ETO15223.1 - 0.0091 15.1 0.7 0.018 14.1 0.5 1.5 1 0 0 1 1 1 1 Sporulation factor SpoIIGA PgaD PF13994.1 ETO15223.1 - 0.03 13.8 1.7 6.3 6.2 0.0 2.5 2 0 0 2 2 2 0 PgaD-like protein Archaeal_AmoA PF12942.2 ETO15223.1 - 0.038 13.7 0.8 0.066 12.9 0.6 1.3 1 0 0 1 1 1 0 Archaeal ammonia monooxygenase subunit A (AmoA) XhlA PF10779.4 ETO15223.1 - 0.15 11.9 0.4 0.34 10.8 0.3 1.6 1 0 0 1 1 1 0 Haemolysin XhlA zf-DHHC PF01529.15 ETO15223.1 - 1.5 8.1 7.2 6 6.2 5.0 2.0 1 1 0 1 1 1 0 DHHC palmitoyltransferase DUF4064 PF13273.1 ETO15223.1 - 3.7 7.7 6.5 3.3 7.8 3.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Pkinase PF00069.20 ETO15224.1 - 1.5e-24 86.5 0.2 2.7e-24 85.7 0.1 1.3 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 ETO15224.1 - 0.015 15.0 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 ETO15224.1 - 0.021 13.8 0.0 0.039 13.0 0.0 1.4 1 1 0 1 1 1 0 Protein tyrosine kinase ELF PF03317.8 ETO15224.1 - 7.6 5.7 10.2 2.4 7.3 3.2 2.2 2 0 0 2 2 2 0 ELF protein Pkinase PF00069.20 ETO15225.1 - 0.013 14.7 0.0 0.025 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain EF-hand_6 PF13405.1 ETO15226.1 - 0.0054 16.5 5.6 0.12 12.3 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 ETO15226.1 - 0.0066 16.0 6.6 0.0069 15.9 1.5 2.8 2 1 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO15226.1 - 0.023 13.9 6.4 2.8 7.4 0.0 3.1 3 0 0 3 3 3 0 EF hand EF-hand_7 PF13499.1 ETO15226.1 - 0.054 13.6 3.9 0.82 9.8 1.0 2.6 1 1 1 2 2 2 0 EF-hand domain pair Kelch_4 PF13418.1 ETO15227.1 - 4.1e-05 23.2 0.0 0.1 12.4 0.0 2.9 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO15227.1 - 0.00044 20.3 0.1 0.016 15.3 0.0 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.1 ETO15227.1 - 0.0047 16.8 0.1 0.95 9.4 0.2 2.6 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.10 ETO15227.1 - 0.0078 15.9 0.1 2.4 8.0 0.0 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.20 ETO15227.1 - 0.068 12.7 0.9 7.3 6.2 0.1 3.1 3 0 0 3 3 3 0 Kelch motif 7tm_1 PF00001.16 ETO15228.1 - 0.0079 15.3 0.5 0.0094 15.1 0.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF70 PF01901.11 ETO15228.1 - 0.076 12.0 2.2 0.12 11.4 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF70 UPF0223 PF05256.7 ETO15229.1 - 0.024 14.7 1.1 3.9 7.6 0.0 2.9 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0223) ENTH PF01417.15 ETO15229.1 - 0.061 13.1 5.9 0.58 10.0 2.7 2.7 1 1 1 2 2 2 0 ENTH domain Lumazine_bd_2 PF12893.2 ETO15229.1 - 0.12 12.9 0.3 12 6.4 0.0 2.3 1 1 1 2 2 2 0 Putative lumazine-binding MecA_N PF05223.6 ETO15229.1 - 0.83 9.7 4.6 8.7 6.4 0.3 2.4 1 1 1 2 2 2 0 NTF2-like N-terminal transpeptidase domain DUF1837 PF08878.6 ETO15229.1 - 5.4 6.5 17.3 1.1 8.7 1.4 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1837) DUF2804 PF10974.3 ETO15230.1 - 0.027 13.3 0.7 0.031 13.1 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2804) Git3_C PF11970.3 ETO15230.1 - 0.084 12.6 1.1 0.14 11.9 0.2 1.9 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term Kelch_2 PF07646.10 ETO15231.1 - 1.4e-07 31.0 0.1 0.00011 21.8 0.1 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 ETO15231.1 - 1.6e-07 30.9 0.1 0.0008 19.1 0.0 2.5 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO15231.1 - 1.2e-06 27.8 0.3 3.3e-05 23.3 0.2 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETO15231.1 - 0.00023 21.1 0.4 0.053 13.7 0.1 2.5 1 1 1 2 2 2 2 Kelch motif Kelch_3 PF13415.1 ETO15231.1 - 0.00039 20.4 0.0 0.0014 18.6 0.0 2.0 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO15231.1 - 0.0091 15.9 0.0 0.056 13.4 0.1 2.1 2 0 0 2 2 2 1 Kelch motif UCH_1 PF13423.1 ETO15232.1 - 0.11 11.8 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF771 PF05595.6 ETO15232.1 - 0.19 11.6 4.6 3.3 7.6 0.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF771) Arch_fla_DE PF04659.8 ETO15232.1 - 0.22 11.3 2.5 0.35 10.7 1.8 1.4 1 0 0 1 1 1 0 Archaeal flagella protein DUF2951 PF11166.3 ETO15234.1 - 0.089 12.6 3.4 0.16 11.7 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) HEAT_2 PF13646.1 ETO15235.1 - 1.3e-22 79.8 0.0 4e-06 27.0 0.0 6.6 4 2 4 8 8 8 6 HEAT repeats HEAT PF02985.17 ETO15235.1 - 6.7e-19 66.2 0.2 0.064 13.3 0.0 8.5 8 0 0 8 8 8 5 HEAT repeat HEAT_EZ PF13513.1 ETO15235.1 - 9.9e-12 44.9 0.0 0.0042 17.5 0.0 6.4 6 0 0 6 6 6 3 HEAT-like repeat Cnd1 PF12717.2 ETO15235.1 - 8.5e-08 32.2 29.6 0.041 13.7 3.5 6.6 2 2 2 4 4 4 4 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 ETO15235.1 - 1.2e-07 31.5 8.3 0.32 10.9 0.1 6.7 6 1 1 7 7 7 2 Protein of unknown function (DUF2435) Vac14_Fab1_bd PF12755.2 ETO15235.1 - 4e-05 23.9 12.2 2.9 8.3 0.5 6.3 3 2 2 6 6 6 3 Vacuolar 14 Fab1-binding region Activator-TraM PF11657.3 ETO15235.1 - 0.014 14.9 5.3 0.15 11.5 0.0 3.6 3 1 0 3 3 3 0 Transcriptional activator TraM VWA_2 PF13519.1 ETO15235.1 - 0.037 14.1 0.0 0.56 10.2 0.0 2.6 2 1 0 2 2 2 0 von Willebrand factor type A domain XkdW PF09636.5 ETO15235.1 - 0.19 11.6 2.2 0.84 9.5 0.0 3.4 4 0 0 4 4 4 0 XkdW protein DUF3944 PF13099.1 ETO15235.1 - 1.6 8.2 10.0 2.1 7.8 0.1 5.5 6 0 0 6 6 6 0 Domain of unknown function (DUF3944) RNA_binding PF01877.12 ETO15235.1 - 2.9 7.9 20.8 1.1 9.2 0.7 6.9 5 3 3 8 8 8 0 RNA binding Colicin PF01024.14 ETO15235.1 - 9.2 5.7 12.2 0.24 10.9 0.5 3.7 2 1 1 3 3 3 0 Colicin pore forming domain CH PF00307.26 ETO15237.1 - 9.2e-20 70.7 0.2 8.7e-08 32.1 0.0 3.1 3 0 0 3 3 3 3 Calponin homology (CH) domain CAMSAP_CH PF11971.3 ETO15237.1 - 0.018 14.6 0.0 0.06 13.0 0.0 1.9 1 0 0 1 1 1 0 CAMSAP CH domain NOSIC PF08060.8 ETO15238.1 - 0.034 13.9 0.2 0.22 11.3 0.1 2.4 1 1 0 1 1 1 0 NOSIC (NUC001) domain DUF4163 PF13739.1 ETO15238.1 - 0.28 11.9 6.4 0.74 10.6 4.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4163) Kelch_4 PF13418.1 ETO15239.1 - 3.7e-06 26.6 0.0 0.012 15.3 0.0 3.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO15239.1 - 3.3e-05 23.3 2.7 0.035 13.6 0.6 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 ETO15239.1 - 0.0004 20.0 2.9 0.51 10.1 0.2 3.8 3 1 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 ETO15239.1 - 0.016 15.3 3.2 27 5.1 0.0 3.9 2 1 1 3 3 3 0 Kelch motif WD40 PF00400.27 ETO15240.1 - 4.3e-64 210.2 25.6 1.1e-12 47.2 0.5 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO15240.1 - 2e-12 46.0 7.1 0.0001 20.6 0.2 5.3 1 1 3 6 6 6 3 Nucleoporin Nup120/160 Mnd1 PF03962.10 ETO15240.1 - 0.0018 17.9 8.4 0.0039 16.8 5.8 1.5 1 0 0 1 1 1 1 Mnd1 family zf-TRAF PF02176.13 ETO15240.1 - 0.0029 17.9 5.1 0.0029 17.9 3.5 2.0 2 0 0 2 2 1 1 TRAF-type zinc finger DUF3601 PF12208.3 ETO15240.1 - 0.024 14.5 0.1 3.9 7.4 0.0 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF3601) PspA_IM30 PF04012.7 ETO15240.1 - 0.028 13.7 3.3 0.042 13.2 2.3 1.2 1 0 0 1 1 1 0 PspA/IM30 family Rootletin PF15035.1 ETO15240.1 - 0.058 13.3 9.0 0.092 12.7 6.2 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF948 PF06103.6 ETO15240.1 - 0.067 13.0 1.7 0.13 12.1 1.2 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF3618 PF12277.3 ETO15240.1 - 0.082 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) DUF342 PF03961.8 ETO15240.1 - 0.12 10.7 9.9 0.18 10.1 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF972 PF06156.8 ETO15240.1 - 0.16 12.3 15.4 0.11 12.8 6.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Laminin_II PF06009.7 ETO15240.1 - 0.24 11.1 7.9 0.46 10.2 5.5 1.4 1 0 0 1 1 1 0 Laminin Domain II bZIP_1 PF00170.16 ETO15240.1 - 0.44 10.5 11.9 0.39 10.6 4.2 2.5 1 1 1 2 2 2 0 bZIP transcription factor FlaC_arch PF05377.6 ETO15240.1 - 0.54 10.1 3.3 10 6.0 0.2 3.0 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Syntaxin PF00804.20 ETO15240.1 - 0.56 10.3 12.9 0.37 10.9 4.0 2.4 1 1 1 2 2 2 0 Syntaxin DUF489 PF04356.7 ETO15240.1 - 0.57 9.7 4.8 1 8.9 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF489) TSC22 PF01166.13 ETO15240.1 - 0.62 10.0 11.8 0.53 10.2 4.5 2.5 1 1 1 2 2 2 0 TSC-22/dip/bun family IncA PF04156.9 ETO15240.1 - 0.98 8.9 9.2 1.5 8.3 6.4 1.2 1 0 0 1 1 1 0 IncA protein Striatin PF08232.7 ETO15240.1 - 1.9 8.7 12.9 2.2 8.6 5.6 2.2 1 1 1 2 2 2 0 Striatin family DivIC PF04977.10 ETO15240.1 - 5.4 6.5 12.3 6 6.4 5.2 2.4 1 1 1 2 2 2 0 Septum formation initiator Ax_dynein_light PF10211.4 ETO15240.1 - 5.9 6.6 18.8 2.6 7.8 8.7 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain DUF3552 PF12072.3 ETO15240.1 - 6.1 5.9 13.2 9.7 5.3 9.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF1664 PF07889.7 ETO15240.1 - 6.5 6.5 8.4 7.9 6.2 4.7 1.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Med4 PF10018.4 ETO15240.1 - 8.4 5.7 9.9 13 5.1 6.9 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 WD40 PF00400.27 ETO15243.1 - 5.7e-23 79.9 5.5 4.7e-12 45.2 0.2 3.4 3 1 0 3 3 3 3 WD domain, G-beta repeat CdCA1 PF10563.4 ETO15243.1 - 0.087 12.3 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Cadmium carbonic anhydrase repeat BBS2_Mid PF14783.1 ETO15243.1 - 0.12 12.2 0.3 0.24 11.1 0.2 1.8 1 1 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region PID_2 PF14719.1 ETO15244.1 - 0.061 12.9 0.8 0.1 12.2 0.5 1.3 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) FA_desaturase PF00487.19 ETO15245.1 - 1e-26 93.9 15.2 1.8e-26 93.1 10.5 1.3 1 0 0 1 1 1 1 Fatty acid desaturase CD99L2 PF12301.3 ETO15247.1 - 0.58 9.8 3.9 0.99 9.0 2.7 1.4 1 0 0 1 1 1 0 CD99 antigen like protein 2 SR-25 PF10500.4 ETO15247.1 - 3 7.2 12.6 5 6.5 8.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BLVR PF06375.6 ETO15247.1 - 4.6 7.0 13.8 9.7 6.0 9.4 1.6 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Prenyltrans_2 PF13249.1 ETO15248.1 - 0.075 13.4 0.1 0.27 11.6 0.0 2.1 1 1 1 2 2 2 0 Prenyltransferase-like CAP_GLY PF01302.20 ETO15249.1 - 4.5e-07 29.4 0.4 9.7e-07 28.4 0.3 1.5 1 0 0 1 1 1 1 CAP-Gly domain Amidase_3 PF01520.13 ETO15251.1 - 0.075 12.8 0.5 0.17 11.6 0.3 1.6 1 1 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase Kelch_6 PF13964.1 ETO15252.1 - 4.2e-11 42.5 9.2 4.5e-06 26.5 0.2 4.7 4 1 1 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO15252.1 - 1.3e-07 31.0 5.9 0.00064 19.3 0.1 4.7 4 1 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO15252.1 - 2.1e-05 23.9 14.1 5.5e-05 22.6 0.3 3.9 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 ETO15252.1 - 0.00066 19.7 0.0 0.34 11.1 0.0 2.9 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO15252.1 - 0.26 11.3 1.6 7.4 6.6 0.0 3.0 3 0 0 3 3 3 0 Kelch motif Abhydrolase_5 PF12695.2 ETO15253.1 - 0.017 14.9 0.0 0.036 13.8 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF633 PF04816.7 ETO15253.1 - 0.12 11.7 0.6 2 7.6 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF633) NicO PF03824.11 ETO15254.1 - 0.045 13.0 0.7 0.066 12.5 0.5 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein FAM176 PF14851.1 ETO15254.1 - 0.16 11.6 3.4 2.8 7.5 3.4 2.2 2 0 0 2 2 2 0 FAM176 family Bd3614_N PF14442.1 ETO15254.1 - 1.5 8.8 6.5 3.2 7.7 4.5 1.5 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal DUF4484 PF14831.1 ETO15254.1 - 7.1 6.6 12.7 14 5.7 8.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) zf-TRAF PF02176.13 ETO15258.1 - 1.4e-07 31.8 0.4 1.4e-07 31.8 0.3 2.4 2 1 0 2 2 2 1 TRAF-type zinc finger Microcin PF03526.8 ETO15258.1 - 0.0068 15.9 0.1 0.011 15.2 0.1 1.3 1 0 0 1 1 1 1 Colicin E1 (microcin) immunity protein zf-H2C2_5 PF13909.1 ETO15258.1 - 0.16 12.2 1.2 1.5 9.2 0.0 3.1 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf-RING_2 PF13639.1 ETO15258.1 - 2.1 8.2 6.9 0.95 9.3 1.6 2.7 2 1 0 2 2 2 0 Ring finger domain SRP40_C PF05022.7 ETO15259.1 - 5.8e-18 65.1 10.3 5.8e-18 65.1 7.2 2.8 3 0 0 3 3 3 1 SRP40, C-terminal domain Glyco_hydro_47 PF01532.15 ETO15260.1 - 6.4e-42 143.7 0.1 7.9e-42 143.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 MRP-S28 PF10213.4 ETO15262.1 - 0.055 13.5 0.5 0.074 13.1 0.4 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein WD40 PF00400.27 ETO15263.1 - 4.7e-37 124.5 20.9 1.6e-12 46.7 2.4 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO15263.1 - 0.0023 16.1 0.1 1.1 7.3 0.0 3.2 3 1 0 3 3 3 2 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO15263.1 - 0.034 14.0 0.0 0.27 11.2 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3601) HARP PF07443.8 ETO15263.1 - 0.061 12.7 0.1 2.7 7.4 0.0 2.7 2 0 0 2 2 2 0 HepA-related protein (HARP) Neur_chan_memb PF02932.11 ETO15264.1 - 0.11 12.3 0.5 0.16 11.8 0.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region zf-TRAF PF02176.13 ETO15265.1 - 2.2e-07 31.1 2.1 1.1e-06 28.9 1.5 2.2 1 0 0 1 1 1 1 TRAF-type zinc finger DUF1644 PF07800.7 ETO15265.1 - 0.00056 19.8 12.2 0.00056 19.8 8.4 2.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1644) IncA PF04156.9 ETO15265.1 - 0.3 10.6 4.6 0.56 9.7 3.2 1.5 1 0 0 1 1 1 0 IncA protein DUF4463 PF14703.1 ETO15265.1 - 0.32 11.5 4.8 0.34 11.4 1.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) zf-C3HC4_2 PF13923.1 ETO15265.1 - 6 6.9 11.5 0.14 12.2 2.2 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Beach PF02138.13 ETO15266.1 - 2.3e-92 309.2 0.7 3e-91 305.5 0.5 2.2 1 1 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 ETO15266.1 - 3.8e-13 49.1 0.8 1.5e-12 47.2 0.5 2.1 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 ETO15266.1 - 3e-08 33.2 1.6 6.6e-06 25.8 0.0 4.9 6 0 0 6 6 6 1 WD domain, G-beta repeat Ycf1 PF05758.7 ETO15267.1 - 0.0071 14.1 6.3 0.0072 14.1 4.4 1.1 1 0 0 1 1 1 1 Ycf1 Ribosomal_60s PF00428.14 ETO15267.1 - 0.015 15.6 1.7 0.015 15.6 1.2 2.4 2 0 0 2 2 1 0 60s Acidic ribosomal protein Daxx PF03344.10 ETO15267.1 - 0.018 13.5 15.8 0.02 13.3 10.9 1.0 1 0 0 1 1 1 0 Daxx Family VID27 PF08553.5 ETO15267.1 - 0.024 12.8 7.7 0.025 12.8 5.3 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein SDA1 PF05285.7 ETO15267.1 - 0.045 13.0 18.2 0.059 12.6 12.6 1.1 1 0 0 1 1 1 0 SDA1 Spore_coat_CotO PF14153.1 ETO15267.1 - 0.059 12.8 11.6 0.074 12.4 8.1 1.2 1 0 0 1 1 1 0 Spore coat protein CotO TFIIF_alpha PF05793.7 ETO15267.1 - 0.25 9.6 22.6 0.32 9.3 15.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GAGA_bind PF06217.7 ETO15267.1 - 0.28 11.1 5.0 0.33 10.8 3.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2457 PF10446.4 ETO15267.1 - 0.51 8.9 19.5 0.68 8.5 13.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BTV_NS2 PF04514.7 ETO15267.1 - 0.55 9.0 11.3 0.8 8.5 7.8 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF1510 PF07423.6 ETO15267.1 - 0.6 9.4 21.0 0.89 8.8 14.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nop14 PF04147.7 ETO15267.1 - 0.69 7.7 17.9 0.86 7.4 12.4 1.1 1 0 0 1 1 1 0 Nop14-like family DDHD PF02862.12 ETO15267.1 - 0.73 9.5 4.9 1.1 9.0 3.4 1.4 1 0 0 1 1 1 0 DDHD domain Peptidase_C37 PF05416.7 ETO15267.1 - 0.81 7.9 5.4 0.91 7.7 3.7 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase DUF2201_N PF13203.1 ETO15267.1 - 0.81 8.8 5.5 1 8.4 3.8 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF2151 PF10221.4 ETO15267.1 - 1.2 7.2 8.5 1.4 6.9 5.9 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator RR_TM4-6 PF06459.7 ETO15267.1 - 2.2 8.1 14.6 3.2 7.5 10.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pal1 PF08316.6 ETO15267.1 - 2.4 8.6 5.1 5.1 7.5 3.6 1.7 1 1 0 1 1 1 0 Pal1 cell morphology protein Merozoite_SPAM PF07133.6 ETO15267.1 - 3.2 7.6 32.9 4.8 7.0 22.8 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) HSP90 PF00183.13 ETO15267.1 - 3.7 5.8 18.9 5.2 5.3 13.1 1.2 1 0 0 1 1 1 0 Hsp90 protein AIF_C PF14721.1 ETO15267.1 - 3.9 7.7 8.7 6.5 7.0 6.1 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Tom37_C PF11801.3 ETO15267.1 - 5.7 6.7 10.3 7.8 6.3 6.8 1.4 1 1 0 1 1 1 0 Tom37 C-terminal domain CDC45 PF02724.9 ETO15267.1 - 9.9 4.0 17.1 13 3.6 11.9 1.1 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.27 ETO15268.1 - 1.1e-38 129.7 20.4 2.5e-12 46.1 0.3 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 ETO15268.1 - 7.4e-07 29.0 0.0 0.0026 17.4 0.0 2.8 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO15268.1 - 0.018 13.3 0.0 0.16 10.2 0.0 2.1 1 1 2 3 3 3 0 Cytochrome D1 heme domain BBS2_Mid PF14783.1 ETO15268.1 - 0.037 13.7 0.0 0.11 12.2 0.0 1.9 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region Str_synth PF03088.11 ETO15268.1 - 0.039 13.9 0.0 0.099 12.6 0.0 1.7 1 0 0 1 1 1 0 Strictosidine synthase DUF3312 PF11768.3 ETO15268.1 - 0.16 10.1 0.0 1.7 6.7 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3312) Pro_isomerase PF00160.16 ETO15269.1 - 3.1e-29 102.1 0.0 3.1e-29 102.1 0.0 2.6 2 1 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PUF PF00806.14 ETO15270.1 - 6.1e-21 72.6 7.0 1.2e-06 27.6 0.1 4.3 4 0 0 4 4 4 4 Pumilio-family RNA binding repeat CPL PF08144.6 ETO15270.1 - 0.029 14.2 0.1 0.094 12.5 0.0 1.9 2 1 0 2 2 2 0 CPL (NUC119) domain DUF758 PF05527.6 ETO15270.1 - 0.045 13.3 0.9 0.085 12.4 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF758) SapB_2 PF03489.12 ETO15270.1 - 0.092 12.7 0.8 19 5.3 0.1 3.3 3 0 0 3 3 3 0 Saposin-like type B, region 2 FDX-ACB PF03147.9 ETO15271.1 - 0.0036 17.4 0.0 0.009 16.1 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain SulA PF03846.9 ETO15271.1 - 0.032 13.9 0.1 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 Cell division inhibitor SulA Band_3_cyto PF07565.8 ETO15271.1 - 4.3 6.7 7.3 0.9 9.0 0.1 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Pkinase PF00069.20 ETO15273.1 - 1.3e-07 31.0 2.7 1.4e-07 30.9 1.5 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO15273.1 - 0.0038 16.3 0.9 0.0052 15.8 0.5 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase DHC_N1 PF08385.7 ETO15274.1 - 3.9e-05 22.2 0.6 6.5e-05 21.5 0.4 1.4 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 DUF45 PF01863.12 ETO15274.1 - 0.0014 18.4 0.2 0.0018 18.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF45 Med14 PF08638.6 ETO15274.1 - 0.065 12.4 1.2 0.086 12.0 0.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit MED14 ASL_C PF08328.6 ETO15274.1 - 0.11 12.3 0.3 0.7 9.7 0.1 2.0 1 1 1 2 2 2 0 Adenylosuccinate lyase C-terminal DHC_N1 PF08385.7 ETO15275.1 - 2e-11 43.0 2.8 2e-11 43.0 2.0 1.7 1 1 1 2 2 2 1 Dynein heavy chain, N-terminal region 1 AF0941-like PF14591.1 ETO15275.1 - 0.016 15.2 2.8 0.19 11.8 0.1 2.2 2 0 0 2 2 2 0 AF0941-like FBP PF07299.6 ETO15275.1 - 0.027 13.8 3.4 0.041 13.2 2.4 1.3 1 0 0 1 1 1 0 Fibronectin-binding protein (FBP) DUF745 PF05335.8 ETO15275.1 - 0.04 13.4 0.6 0.04 13.4 0.4 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF745) OGG_N PF07934.7 ETO15275.1 - 0.19 11.6 4.1 0.1 12.5 0.4 2.2 1 1 0 2 2 2 0 8-oxoguanine DNA glycosylase, N-terminal domain F-box-like PF12937.2 ETO15276.1 - 0.00036 20.2 0.3 0.00086 18.9 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 ETO15276.1 - 0.032 13.8 0.1 0.085 12.5 0.1 1.7 1 0 0 1 1 1 0 F-box domain Phage_connect_1 PF05135.8 ETO15277.1 - 0.0094 16.1 0.2 0.043 13.9 0.1 2.1 1 0 0 1 1 1 1 Phage gp6-like head-tail connector protein DUF2098 PF09871.4 ETO15277.1 - 4.8 7.1 8.3 0.34 10.8 0.3 2.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2098) DUF1294 PF06961.8 ETO15278.1 - 0.059 13.3 0.5 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1294) Ion_trans PF00520.26 ETO15279.1 - 6.8e-08 32.0 8.3 1.2e-07 31.1 5.8 1.5 1 0 0 1 1 1 1 Ion transport protein Ion_trans_N PF08412.5 ETO15279.1 - 0.51 9.6 3.7 0.23 10.8 0.4 2.0 2 0 0 2 2 2 0 Ion transport protein N-terminal cNMP_binding PF00027.24 ETO15280.1 - 5.3e-07 29.3 0.0 1.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.11 ETO15280.1 - 3.5e-06 26.6 6.6 6.6e-06 25.7 4.6 1.4 1 0 0 1 1 1 1 Ion channel RepB PF07506.6 ETO15280.1 - 0.002 18.0 2.6 0.002 18.0 1.8 1.5 2 0 0 2 2 2 1 RepB plasmid partitioning protein DegQ PF08181.6 ETO15280.1 - 0.0023 17.5 0.0 0.0048 16.5 0.0 1.5 1 0 0 1 1 1 1 DegQ (SacQ) family DDE_Tnp_IS66 PF03050.9 ETO15280.1 - 0.019 14.2 1.7 0.029 13.6 1.2 1.2 1 0 0 1 1 1 0 Transposase IS66 family Consortin_C PF15281.1 ETO15280.1 - 0.21 11.1 2.1 0.29 10.6 0.0 2.2 3 0 0 3 3 3 0 Consortin C-terminus Transposase_31 PF04754.7 ETO15282.1 - 7.6e-36 123.4 0.1 8.5e-36 123.2 0.0 1.0 1 0 0 1 1 1 1 Putative transposase, YhgA-like Guanylate_cyc PF00211.15 ETO15283.1 - 1.1e-09 37.9 0.2 1.7e-09 37.3 0.1 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain NRDE-2 PF08424.5 ETO15285.1 - 0.65 8.8 5.0 1.2 8.0 3.4 1.4 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference DUF3046 PF11248.3 ETO15286.1 - 0.0041 17.0 0.1 0.01 15.8 0.1 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF3046) AlcCBM31 PF11606.3 ETO15286.1 - 0.015 15.2 0.1 0.021 14.8 0.1 1.3 1 0 0 1 1 1 0 Family 31 carbohydrate binding protein EBA-175_VI PF11556.3 ETO15286.1 - 0.045 13.8 2.8 0.085 12.9 2.0 1.5 1 1 0 1 1 1 0 Erythrocyte binding antigen 175 Wbp11 PF09429.5 ETO15286.1 - 0.14 12.1 0.4 0.21 11.6 0.3 1.2 1 0 0 1 1 1 0 WW domain binding protein 11 WD40 PF00400.27 ETO15287.1 - 1.2e-35 120.0 16.5 2.8e-10 39.6 0.0 5.2 4 1 1 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO15287.1 - 1.3e-08 33.4 0.2 0.0099 14.0 0.0 3.0 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO15289.1 - 5.7e-08 32.6 0.7 0.00049 20.1 0.4 2.3 1 1 1 2 2 2 2 Kelch motif Kelch_1 PF01344.20 ETO15289.1 - 1.6e-07 30.7 0.5 7.1e-06 25.4 0.3 2.2 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.1 ETO15289.1 - 9.7e-07 28.4 0.0 0.011 15.4 0.0 2.3 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO15289.1 - 0.0032 17.1 1.5 0.73 9.6 1.0 2.7 2 1 0 2 2 2 1 Kelch motif Kelch_5 PF13854.1 ETO15289.1 - 0.036 14.0 0.3 1.2 9.2 0.7 2.2 2 0 0 2 2 2 0 Kelch motif DUF1153 PF06627.6 ETO15290.1 - 0.072 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1153) Kelch_2 PF07646.10 ETO15291.1 - 0.00039 20.0 1.1 13 5.6 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO15291.1 - 0.0011 18.6 0.1 0.87 9.4 0.0 2.8 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO15291.1 - 0.0028 17.1 0.3 2.2 7.9 0.0 4.1 4 0 0 4 4 4 1 Kelch motif WD40 PF00400.27 ETO15292.1 - 6.2e-33 111.4 8.1 5.7e-10 38.7 0.6 5.9 5 1 0 5 5 5 5 WD domain, G-beta repeat zf-TRAF PF02176.13 ETO15292.1 - 1.5e-06 28.4 4.4 5.7e-06 26.6 3.0 2.1 1 0 0 1 1 1 1 TRAF-type zinc finger PD40 PF07676.7 ETO15292.1 - 7.4e-05 22.3 1.7 0.19 11.4 0.0 4.6 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Kelch_6 PF13964.1 ETO15292.1 - 0.021 14.9 5.3 15 5.9 0.1 4.5 4 0 0 4 4 4 0 Kelch motif DARPP-32 PF05395.7 ETO15292.1 - 0.53 10.4 8.0 1.1 9.4 5.5 1.4 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 TFR_dimer PF04253.10 ETO15292.1 - 0.62 9.6 6.1 2.7 7.6 0.3 3.5 3 0 0 3 3 3 0 Transferrin receptor-like dimerisation domain Kelch_1 PF01344.20 ETO15292.1 - 0.84 9.2 4.0 29 4.2 0.0 3.5 3 0 0 3 3 3 0 Kelch motif IF-2 PF11987.3 ETO15293.1 - 2.4e-15 56.3 0.0 4.2e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 ETO15293.1 - 0.00045 20.2 0.0 0.00091 19.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Peptidase_S49_N PF08496.5 ETO15293.1 - 0.0014 18.4 2.7 0.0027 17.5 1.8 1.4 1 0 0 1 1 1 1 Peptidase family S49 N-terminal HDAC4_Gln PF12203.3 ETO15293.1 - 0.051 13.5 5.0 0.1 12.5 3.5 1.4 1 0 0 1 1 1 0 Glutamine rich N terminal domain of histone deacetylase 4 DUF3334 PF11813.3 ETO15293.1 - 0.34 10.4 1.7 10 5.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3334) GTP_EFTU PF00009.22 ETO15294.1 - 1.7e-27 96.0 0.3 1.8e-21 76.4 0.0 3.0 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 ETO15294.1 - 1.1e-05 25.3 0.0 2.5e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 ETO15294.1 - 4.4e-05 23.1 0.0 0.00039 20.0 0.0 2.2 1 1 0 2 2 2 1 Conserved hypothetical ATP binding protein Miro PF08477.8 ETO15294.1 - 0.013 15.9 0.0 0.19 12.2 0.0 2.8 1 1 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 ETO15294.1 - 0.66 9.7 5.8 2.7 7.7 0.0 3.5 2 2 1 3 3 3 0 Dynamin family DUF1886 PF09171.5 ETO15296.1 - 0.065 12.2 0.0 0.065 12.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1886) Virul_fac_BrkB PF03631.10 ETO15299.1 - 0.06 12.6 1.1 0.067 12.5 0.3 1.4 1 1 0 1 1 1 0 Virulence factor BrkB PNTB PF02233.11 ETO15300.1 - 4.4e-182 606.0 17.5 4.4e-182 606.0 12.1 2.2 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 ETO15300.1 - 2.6e-55 186.5 0.3 2.6e-55 186.5 0.2 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 ETO15300.1 - 1.7e-43 147.9 0.0 3e-43 147.0 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 ETO15300.1 - 5.5e-32 109.7 2.5 5.5e-32 109.7 1.8 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 ETO15300.1 - 0.0041 16.3 0.3 0.79 8.8 0.0 3.4 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_31 PF13847.1 ETO15300.1 - 0.017 14.6 0.0 0.047 13.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Pyr_redox PF00070.22 ETO15300.1 - 0.093 13.1 0.6 0.29 11.5 0.4 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETO15300.1 - 0.13 12.0 0.9 0.67 9.8 0.3 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3035 PF11233.3 ETO15301.1 - 0.11 12.5 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) RE_MjaI PF09568.5 ETO15302.1 - 0.012 15.1 0.9 0.014 14.9 0.6 1.1 1 0 0 1 1 1 0 MjaI restriction endonuclease DUF1448 PF07289.6 ETO15303.1 - 8.1e-48 163.0 2.5 6.8e-47 160.0 1.7 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1448) bPH_3 PF14470.1 ETO15303.1 - 2.3e-05 24.5 0.0 2.3e-05 24.5 0.0 3.9 3 0 0 3 3 3 1 Bacterial PH domain Ank_2 PF12796.2 ETO15304.1 - 1.5e-16 60.5 0.0 3.4e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO15304.1 - 1.1e-13 50.2 0.3 1.3e-05 24.7 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 ETO15304.1 - 1.9e-13 50.5 0.1 3e-11 43.5 0.1 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO15304.1 - 1.1e-12 47.7 0.6 1.1e-06 28.6 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO15304.1 - 5.3e-12 44.7 0.1 0.0012 18.9 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat AAA_12 PF13087.1 ETO15304.1 - 0.054 12.8 0.4 0.081 12.2 0.3 1.4 1 0 0 1 1 1 0 AAA domain DFP PF04127.10 ETO15305.1 - 0.00017 21.2 0.0 0.00021 20.9 0.0 1.2 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein PsbK PF02533.10 ETO15306.1 - 0.037 13.9 0.3 0.062 13.2 0.2 1.4 1 0 0 1 1 1 0 Photosystem II 4 kDa reaction centre component WD40 PF00400.27 ETO15307.1 - 1.4e-06 27.9 3.7 1.2e-05 24.9 0.6 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF912 PF06024.7 ETO15307.1 - 0.11 12.5 11.7 0.29 11.1 4.1 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Mucin PF01456.12 ETO15307.1 - 0.18 11.5 12.3 0.34 10.6 8.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein G-alpha PF00503.15 ETO15308.1 - 2.4e-06 26.4 0.1 2.8e-06 26.3 0.1 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Pox_E10 PF04805.7 ETO15308.1 - 0.17 11.4 1.0 1.3 8.6 0.0 2.5 1 1 2 3 3 3 0 E10-like protein conserved region WD40 PF00400.27 ETO15310.1 - 8.9e-15 53.9 8.2 9.5e-10 37.9 0.7 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO15310.1 - 0.0037 15.4 1.2 0.029 12.5 0.1 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF2721 PF11026.3 ETO15311.1 - 0.29 10.7 2.2 0.84 9.2 1.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Secretin_N_2 PF07655.8 ETO15311.1 - 4.2 7.8 23.9 0.094 13.1 11.3 2.0 2 0 0 2 2 2 0 Secretin N-terminal domain SPRY PF00622.23 ETO15312.1 - 0.0078 16.3 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 SPRY domain Hemagglutinin PF00509.13 ETO15312.1 - 0.34 8.9 3.0 0.54 8.3 2.0 1.2 1 0 0 1 1 1 0 Haemagglutinin DUF1664 PF07889.7 ETO15313.1 - 0.54 10.0 5.6 0.39 10.5 2.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3446 PF11928.3 ETO15314.1 - 0.0037 17.4 0.9 0.21 11.8 1.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3446) SR-25 PF10500.4 ETO15314.1 - 0.079 12.4 7.3 0.1 12.0 5.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SAM_2 PF07647.12 ETO15316.1 - 0.01 15.6 0.1 0.015 15.0 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO15316.1 - 0.012 15.8 0.1 0.016 15.3 0.1 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) HSP90 PF00183.13 ETO15317.1 - 2.2e-48 165.0 2.6 3.2e-48 164.4 1.8 1.2 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 ETO15317.1 - 2.8e-11 43.2 0.1 6e-11 42.1 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 ETO15317.1 - 9.2e-10 38.2 0.1 1.5e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 PF00183.13 ETO15318.1 - 3.8e-89 299.5 3.1 4.9e-89 299.1 2.2 1.0 1 0 0 1 1 1 1 Hsp90 protein DUF4484 PF14831.1 ETO15318.1 - 0.042 13.9 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) DnaJ-X PF14308.1 ETO15319.1 - 0.097 11.9 2.2 0.14 11.4 1.5 1.3 1 0 0 1 1 1 0 X-domain of DnaJ-containing ATP-synt_B PF00430.13 ETO15319.1 - 0.93 9.2 3.3 1.3 8.8 2.3 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Sec62 PF03839.11 ETO15319.1 - 6.9 6.0 7.1 12 5.2 4.9 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 SPRY PF00622.23 ETO15320.1 - 0.0011 18.9 0.1 0.003 17.6 0.0 1.9 2 1 0 2 2 2 1 SPRY domain Diphthamide_syn PF01866.12 ETO15321.1 - 0.021 14.0 4.0 0.029 13.6 2.8 1.1 1 0 0 1 1 1 0 Putative diphthamide synthesis protein UPF0020 PF01170.13 ETO15321.1 - 0.19 11.2 1.5 0.27 10.7 0.1 1.8 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 AAA_21 PF13304.1 ETO15321.1 - 0.31 10.9 8.3 0.44 10.4 5.8 1.2 1 0 0 1 1 1 0 AAA domain DUF3829 PF12889.2 ETO15321.1 - 1.2 8.2 13.8 1.7 7.7 9.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Kelch_1 PF01344.20 ETO15322.1 - 0.016 14.7 2.6 0.13 11.7 0.4 3.0 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.1 ETO15322.1 - 0.025 14.3 2.3 11 5.8 0.0 3.5 2 1 1 3 3 3 0 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO15322.1 - 0.13 12.1 0.7 5.1 7.0 0.1 3.2 3 0 0 3 3 3 0 Kelch motif Nucleoplasmin PF03066.10 ETO15322.1 - 1.2 8.6 9.5 6 6.3 2.3 2.3 2 0 0 2 2 2 0 Nucleoplasmin Adeno_E1B_55K PF01696.12 ETO15323.1 - 0.13 10.7 1.3 0.17 10.3 0.9 1.1 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen WD40 PF00400.27 ETO15324.1 - 2.3e-07 30.4 15.8 0.00024 20.8 0.1 3.8 4 1 0 4 4 4 3 WD domain, G-beta repeat SNF2_N PF00176.18 ETO15326.1 - 1.4e-69 234.2 0.2 1.4e-69 234.2 0.2 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Chromo PF00385.19 ETO15326.1 - 1.9e-16 59.4 2.0 1.6e-07 30.8 0.5 3.2 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 ETO15326.1 - 7.1e-15 54.6 0.0 2.3e-14 53.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETO15326.1 - 0.0096 15.4 0.0 0.044 13.2 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.26 ETO15326.1 - 0.017 15.1 2.1 0.1 12.6 0.2 3.1 3 0 0 3 3 3 0 Myb-like DNA-binding domain Pkinase PF00069.20 ETO15328.1 - 5.2e-39 133.9 0.0 9.9e-39 133.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO15328.1 - 6e-18 64.8 0.0 1.2e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase NIF PF03031.13 ETO15329.1 - 1.1e-18 67.3 0.0 8.3e-17 61.3 0.0 2.1 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Bac_small_YrzI PF09501.5 ETO15330.1 - 0.27 11.1 2.4 0.62 10.0 1.6 1.5 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) Sporozoite_P67 PF05642.6 ETO15330.1 - 0.32 8.8 2.9 0.32 8.8 2.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pkinase PF00069.20 ETO15332.1 - 4.5e-27 94.8 0.6 6.4e-27 94.3 0.4 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO15332.1 - 5e-10 38.8 0.2 8e-10 38.2 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETO15332.1 - 6.7e-05 22.7 0.0 0.01 15.6 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Nucleoplasmin PF03066.10 ETO15332.1 - 0.062 12.8 5.4 0.12 11.8 3.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin zf-C3HC4_2 PF13923.1 ETO15334.1 - 0.001 19.0 3.6 0.011 15.7 2.5 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Tet_JBP PF12851.2 ETO15334.1 - 0.0023 17.2 1.6 0.0026 17.0 1.1 1.0 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Cys_knot PF00007.17 ETO15334.1 - 0.011 15.7 6.1 0.014 15.4 4.2 1.2 1 0 0 1 1 1 0 Cystine-knot domain DUF3671 PF12420.3 ETO15335.1 - 0.67 9.9 9.3 0.95 9.4 6.4 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF2207 PF09972.4 ETO15335.1 - 0.69 8.4 5.8 0.71 8.3 4.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4131 PF13567.1 ETO15335.1 - 1.8 7.9 5.0 2.5 7.4 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) zf-LITAF-like PF10601.4 ETO15335.1 - 4.6 7.1 6.9 1.4 8.7 2.3 1.8 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain WD40 PF00400.27 ETO15336.1 - 1.7e-41 138.6 11.9 7e-12 44.7 0.4 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO15336.1 - 2.7e-09 35.7 0.5 0.00042 18.5 0.1 3.9 1 1 3 4 4 4 4 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO15336.1 - 0.0051 16.5 0.4 2 8.1 0.0 2.9 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A DUF1900 PF08954.6 ETO15336.1 - 0.11 11.9 0.4 3.3 7.2 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF1900) WD40 PF00400.27 ETO15337.1 - 3.1e-13 49.0 16.2 1.5e-07 31.0 0.3 4.7 4 1 1 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO15337.1 - 0.0017 16.5 0.3 0.33 9.0 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 DUF2026 PF09641.5 ETO15337.1 - 0.094 12.0 0.4 0.31 10.3 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2026) HA2 PF04408.18 ETO15339.1 - 2.1e-20 72.6 3.1 9.5e-20 70.5 0.0 2.7 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 ETO15339.1 - 1e-11 44.5 0.0 2.4e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 ETO15339.1 - 6.3e-11 42.1 1.0 1e-10 41.4 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Complex1_LYR PF05347.10 ETO15339.1 - 0.76 9.6 0.0 0.76 9.6 0.0 2.6 4 0 0 4 4 4 0 Complex 1 protein (LYR family) DUF1777 PF08648.7 ETO15340.1 - 2.3e-21 76.3 43.7 2.8e-21 76.0 30.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 ETO15340.1 - 0.023 13.1 36.5 0.025 13.0 25.3 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 ORC6 PF05460.8 ETO15340.1 - 0.89 8.5 16.2 0.91 8.5 11.2 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) WD40 PF00400.27 ETO15341.1 - 0.00043 20.0 6.6 0.022 14.6 2.7 3.3 2 2 0 2 2 2 2 WD domain, G-beta repeat MIP-T3 PF10243.4 ETO15342.1 - 0.56 8.6 36.4 0.66 8.3 25.2 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 zf-RING_2 PF13639.1 ETO15343.1 - 0.0038 17.0 2.2 0.011 15.5 1.5 1.8 1 0 0 1 1 1 1 Ring finger domain Alpha-mann_mid PF09261.6 ETO15343.1 - 0.027 14.6 0.1 0.064 13.4 0.1 1.7 1 0 0 1 1 1 0 Alpha mannosidase, middle domain DUF1325 PF07039.6 ETO15343.1 - 0.062 12.9 0.2 0.99 9.0 0.0 2.4 3 0 0 3 3 3 0 SGF29 tudor-like domain Cys_knot PF00007.17 ETO15343.1 - 0.31 11.1 8.4 0.13 12.3 3.8 1.9 2 0 0 2 2 2 0 Cystine-knot domain Pox_Ag35 PF03286.9 ETO15343.1 - 0.4 10.1 4.3 0.42 10.1 0.4 2.2 2 1 0 2 2 2 0 Pox virus Ag35 surface protein GATase_7 PF13537.1 ETO15346.1 - 1.2e-11 44.3 0.0 6e-11 42.1 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 ETO15346.1 - 3.4e-08 33.5 0.0 5.6e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Asn_synthase PF00733.16 ETO15347.1 - 2.9e-07 30.2 0.0 4.3e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.12 ETO15347.1 - 0.0096 14.8 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 ETO15348.1 - 6.4e-28 97.9 0.3 9e-28 97.4 0.2 1.3 1 0 0 1 1 1 1 Asparagine synthase IncA PF04156.9 ETO15348.1 - 0.78 9.3 4.1 1.2 8.7 2.8 1.2 1 0 0 1 1 1 0 IncA protein PIN_2 PF10130.4 ETO15348.1 - 2.1 8.3 5.5 7.4 6.6 1.2 2.3 1 1 1 2 2 2 0 PIN domain SF3b10 PF07189.6 ETO15348.1 - 2.2 8.1 5.1 0.5 10.2 0.3 2.3 3 0 0 3 3 3 0 Splicing factor 3B subunit 10 (SF3b10) NIF PF03031.13 ETO15351.1 - 1.3e-17 63.9 1.5 3.5e-17 62.5 0.2 2.4 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 ETO15351.1 - 0.0017 18.1 0.0 0.0039 17.0 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain TFIIA PF03153.8 ETO15351.1 - 0.0031 17.4 21.9 0.0031 17.4 15.2 5.1 5 0 0 5 5 5 1 Transcription factor IIA, alpha/beta subunit Porphobil_deam PF01379.15 ETO15352.1 - 7.4e-62 208.0 0.0 1.4e-61 207.1 0.0 1.4 1 1 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 ETO15352.1 - 3.7e-08 33.3 0.2 7.6e-08 32.3 0.2 1.6 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain DUF2116 PF09889.4 ETO15353.1 - 0.0042 16.8 1.2 0.012 15.4 0.4 2.1 2 0 0 2 2 2 1 Uncharacterized protein containing a Zn-ribbon (DUF2116) Pkinase PF00069.20 ETO15354.1 - 2.3e-06 26.9 0.0 3.8e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO15354.1 - 6.9e-05 22.0 0.0 0.00013 21.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 ETO15355.1 - 3e-59 200.3 1.0 5.1e-59 199.5 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO15355.1 - 2.4e-29 102.2 0.3 6.4e-29 100.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 ETO15355.1 - 0.00026 20.1 0.2 0.0006 18.9 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETO15355.1 - 0.00091 18.2 0.0 0.0031 16.5 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 ETO15355.1 - 0.0059 16.3 0.3 0.018 14.7 0.1 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 ETO15355.1 - 0.013 14.8 0.6 0.052 12.8 0.0 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 ETO15355.1 - 0.048 13.2 0.4 0.048 13.2 0.3 2.4 2 1 0 2 2 2 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 ETO15355.1 - 0.23 10.2 7.8 0.0092 14.8 1.2 1.7 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase WD40 PF00400.27 ETO15356.1 - 4.5e-10 39.0 4.5 0.0017 18.1 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat B56 PF01603.15 ETO15357.1 - 2.1e-96 323.0 13.6 3.7e-96 322.2 9.4 1.3 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Cyt-b5 PF00173.23 ETO15358.1 - 3.3e-12 46.0 0.0 7.1e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3684 PF12449.3 ETO15358.1 - 0.011 13.3 0.2 0.017 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3684) BAMBI PF06211.7 ETO15358.1 - 0.067 13.1 1.5 0.089 12.8 0.3 1.7 2 0 0 2 2 2 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain Rad60-SLD PF11976.3 ETO15358.1 - 0.23 11.1 1.7 3.6 7.3 0.0 2.8 2 1 1 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like UQ_con PF00179.21 ETO15359.1 - 1.5e-48 163.7 0.1 3.2e-48 162.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 ETO15359.1 - 1.4e-05 24.8 0.2 3e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 ETO15359.1 - 8.7e-05 22.3 0.4 0.00013 21.7 0.3 1.4 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 ETO15359.1 - 0.074 12.7 0.1 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 UEV domain POPLD PF08170.7 ETO15359.1 - 0.65 9.8 5.6 5 7.0 0.0 3.1 3 0 0 3 3 3 0 POPLD (NUC188) domain LIM PF00412.17 ETO15360.1 - 1.4e-07 31.4 5.0 1.4e-07 31.4 3.5 3.4 3 1 0 3 3 3 1 LIM domain TNFR_c6 PF00020.13 ETO15360.1 - 1.2 9.3 10.2 1.7 8.7 0.4 3.4 3 0 0 3 3 3 0 TNFR/NGFR cysteine-rich region TPR_12 PF13424.1 ETO15361.1 - 2.2e-12 46.7 3.4 1.7e-11 43.8 0.2 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO15361.1 - 8.6e-07 28.6 0.1 0.00015 21.5 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO15361.1 - 0.00017 21.0 2.4 0.00025 20.5 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO15361.1 - 0.00034 20.2 2.8 0.082 12.5 0.0 2.3 2 0 0 2 2 2 2 TPR repeat DUF2225 PF09986.4 ETO15361.1 - 0.0033 16.9 6.4 0.0056 16.1 4.4 1.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_2 PF07719.12 ETO15361.1 - 0.0043 16.8 1.5 0.18 11.8 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO15361.1 - 0.019 14.7 1.8 0.071 12.9 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETO15361.1 - 0.44 10.4 3.1 5.4 7.0 0.0 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat PhoU PF01895.14 ETO15361.1 - 1.6 9.1 4.7 7.6 7.0 1.1 2.9 1 1 1 2 2 2 0 PhoU domain DUF4363 PF14276.1 ETO15361.1 - 1.8 8.2 8.2 4 7.1 5.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4363) Longin PF13774.1 ETO15362.1 - 7.3e-07 28.6 0.3 1.8e-06 27.4 0.0 1.9 2 1 0 2 2 2 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 ETO15362.1 - 0.00055 19.4 0.4 0.00055 19.4 0.2 2.0 1 1 1 2 2 2 1 Synaptobrevin DUF2202 PF09968.4 ETO15363.1 - 0.0069 16.0 0.5 0.015 14.9 0.4 1.6 1 0 0 1 1 1 1 Uncharacterized protein domain (DUF2202) DUF1049 PF06305.6 ETO15363.1 - 0.035 13.5 0.1 0.035 13.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) RRF PF01765.14 ETO15363.1 - 0.04 13.3 0.1 0.04 13.3 0.1 3.1 3 0 0 3 3 3 0 Ribosome recycling factor Patched PF02460.13 ETO15363.1 - 4.3 5.1 12.6 0.46 8.3 5.6 1.5 1 1 0 2 2 2 0 Patched family ETRAMP PF09716.5 ETO15363.1 - 5.2 7.0 8.1 0.56 10.1 0.8 2.5 2 2 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DNA_pol_A_exo1 PF01612.15 ETO15364.1 - 1.4e-15 57.1 1.6 4.5e-15 55.5 1.1 1.8 1 1 0 1 1 1 1 3'-5' exonuclease MMR_HSR1 PF01926.18 ETO15366.1 - 1.4e-13 50.7 0.0 1.8e-12 47.2 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase IIGP PF05049.8 ETO15366.1 - 5.2e-06 25.5 0.0 1.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.13 ETO15366.1 - 5.8e-06 25.6 0.0 1.3e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 ETO15366.1 - 0.0001 21.8 0.2 0.012 15.0 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 ETO15366.1 - 0.00043 20.1 3.2 0.41 10.4 0.0 3.7 2 2 1 4 4 4 2 Dynamin family DUF258 PF03193.11 ETO15366.1 - 0.00064 18.9 0.0 0.0014 17.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 DUF3295 PF11702.3 ETO15366.1 - 0.0017 17.4 4.7 0.0027 16.7 3.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) AAA_30 PF13604.1 ETO15366.1 - 0.011 15.3 0.2 0.027 14.0 0.0 1.7 1 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 ETO15366.1 - 0.013 15.8 0.9 0.29 11.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 ETO15366.1 - 0.017 15.1 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF2457 PF10446.4 ETO15366.1 - 0.025 13.3 11.2 0.045 12.4 7.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) MobB PF03205.9 ETO15366.1 - 0.069 12.8 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 ETO15366.1 - 0.29 11.9 1.6 0.94 10.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain FLO_LFY PF01698.11 ETO15366.1 - 0.4 9.4 7.0 0.55 9.0 4.9 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein NOA36 PF06524.7 ETO15366.1 - 0.67 9.1 8.1 0.98 8.6 5.6 1.1 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.1 ETO15366.1 - 1.7 9.0 17.2 0.64 10.3 9.7 1.9 2 0 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.1 ETO15366.1 - 2.5 7.7 6.6 0.93 9.1 2.5 1.8 2 0 0 2 2 2 0 FAM176 family Mitofilin PF09731.4 ETO15368.1 - 0.026 13.2 0.2 0.029 13.0 0.2 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Sec6 PF06046.8 ETO15368.1 - 0.03 12.4 0.1 0.03 12.4 0.1 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec6 Peptidase_C48 PF02902.14 ETO15372.1 - 2.5e-27 95.9 7.7 2.5e-27 95.9 5.3 2.5 3 0 0 3 3 3 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C14 PF00656.17 ETO15373.1 - 5.9e-05 22.8 0.0 7e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Caspase domain WD40 PF00400.27 ETO15374.1 - 2e-06 27.4 2.5 0.00024 20.8 0.5 2.4 2 1 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO15374.1 - 0.078 11.1 0.0 0.078 11.1 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Prok-RING_1 PF14446.1 ETO15375.1 - 2.8e-05 23.7 3.2 6.5e-05 22.5 2.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 C1_1 PF00130.17 ETO15375.1 - 0.00052 19.6 5.6 0.0011 18.6 3.9 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Ribosomal_L37ae PF01780.14 ETO15375.1 - 0.041 13.7 1.7 0.21 11.4 1.2 2.2 1 0 0 1 1 1 0 Ribosomal L37ae protein family PHD PF00628.24 ETO15375.1 - 0.073 12.7 6.1 0.23 11.1 4.2 1.9 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.1 ETO15375.1 - 1.4 8.8 13.9 4.2 7.2 9.6 1.9 1 1 0 1 1 1 0 Ring finger domain DUF1116 PF06545.6 ETO15377.1 - 0.0015 17.6 0.3 0.0021 17.2 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1116) E6 PF00518.12 ETO15377.1 - 0.005 17.1 1.5 0.011 16.0 1.0 1.7 1 0 0 1 1 1 1 Early Protein (E6) IFT20 PF14931.1 ETO15377.1 - 0.05 13.4 0.7 0.05 13.4 0.5 3.6 1 1 1 3 3 3 0 Intraflagellar transport complex B, subunit 20 CRISPR_Cse1 PF09481.5 ETO15377.1 - 0.4 9.3 4.4 0.17 10.6 0.5 1.8 1 1 1 2 2 2 0 CRISPR-associated protein Cse1 (CRISPR_cse1) SATase_N PF06426.9 ETO15377.1 - 0.67 10.2 3.9 0.54 10.5 1.0 2.0 1 1 0 2 2 2 0 Serine acetyltransferase, N-terminal DUF3708 PF12501.3 ETO15377.1 - 0.96 9.2 3.6 1.2 9.0 0.1 2.3 1 1 2 3 3 3 0 Phosphate ATP-binding cassette transporter RolB_RolC PF02027.12 ETO15377.1 - 2.1 7.4 5.3 1.9 7.6 0.7 2.4 1 1 1 2 2 2 0 RolB/RolC glucosidase family DUF1319 PF07028.6 ETO15377.1 - 2.2 8.5 17.7 0.48 10.6 4.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) IncA PF04156.9 ETO15377.1 - 3.2 7.3 27.1 2.6 7.6 8.6 2.2 1 1 1 2 2 2 0 IncA protein Fib_alpha PF08702.5 ETO15377.1 - 6.2 6.9 27.0 5.9 7.0 3.2 3.0 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.14 ETO15377.1 - 6.3 4.5 16.3 19 2.9 11.1 1.7 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family AHS1 PF02682.11 ETO15377.1 - 8.7 5.7 9.0 6.6 6.1 2.3 2.1 1 1 1 2 2 2 0 Allophanate hydrolase subunit 1 Peptidase_S49_N PF08496.5 ETO15379.1 - 0.071 12.9 2.3 0.054 13.2 0.4 1.7 1 1 1 2 2 2 0 Peptidase family S49 N-terminal Med19 PF10278.4 ETO15379.1 - 0.18 11.4 7.3 0.3 10.7 5.1 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 WD40 PF00400.27 ETO15380.1 - 3.3e-62 204.3 26.5 3.4e-12 45.7 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO15380.1 - 3.1e-09 35.5 1.9 0.043 11.9 0.0 5.3 2 1 4 6 6 6 4 Nucleoporin Nup120/160 Alpha-L-AF_C PF06964.7 ETO15380.1 - 0.048 13.4 0.0 4.4 7.0 0.0 2.2 2 0 0 2 2 2 0 Alpha-L-arabinofuranosidase C-terminus DUF417 PF04224.7 ETO15381.1 - 0.098 12.0 0.4 4.1 6.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF417 WD40 PF00400.27 ETO15383.1 - 8e-16 57.2 2.5 1.7e-08 34.0 0.0 3.4 3 1 0 3 3 3 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 ETO15383.1 - 0.054 13.2 1.9 8.9 6.1 0.4 3.0 1 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 ETO15383.1 - 0.067 11.9 1.2 0.15 10.7 0.3 2.0 1 1 1 2 2 2 0 Nup133 N terminal like Marek_SORF3 PF07153.6 ETO15383.1 - 0.083 11.5 0.2 0.17 10.5 0.1 1.5 1 1 0 1 1 1 0 Marek's disease-like virus SORF3 protein 2OG-FeII_Oxy_2 PF13532.1 ETO15384.1 - 2.1e-31 109.2 0.1 3.3e-31 108.6 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.27 ETO15385.1 - 1.4e-164 528.8 45.2 1e-11 44.2 0.1 16.4 16 0 0 16 16 16 16 WD domain, G-beta repeat NACHT PF05729.7 ETO15385.1 - 2.7e-10 40.1 0.0 5.8e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO15385.1 - 1.9e-06 28.2 0.2 1.9e-06 28.2 0.1 4.3 2 1 1 3 3 3 1 AAA domain Pentapeptide_4 PF13599.1 ETO15385.1 - 3.6e-05 23.4 1.3 3.6e-05 23.4 0.9 2.1 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETO15385.1 - 3.7e-05 22.8 4.8 7.8e-05 21.8 3.3 1.4 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) AAA_22 PF13401.1 ETO15385.1 - 0.00038 20.5 0.0 0.0015 18.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain Pentapeptide_3 PF13576.1 ETO15385.1 - 0.00066 19.5 1.2 0.0016 18.3 0.8 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA_17 PF13207.1 ETO15385.1 - 0.0013 19.5 4.3 0.002 18.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain UPF0079 PF02367.12 ETO15385.1 - 0.013 15.1 0.1 0.11 12.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 CUE PF02845.11 ETO15385.1 - 0.014 14.8 1.2 0.031 13.7 0.1 2.3 2 0 0 2 2 2 0 CUE domain PD40 PF07676.7 ETO15385.1 - 1.6 8.5 19.9 32 4.3 0.0 8.0 9 0 0 9 9 9 0 WD40-like Beta Propeller Repeat 3-HAO PF06052.7 ETO15386.1 - 1.1e-45 154.7 0.1 1.6e-45 154.2 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 ETO15386.1 - 0.00047 19.5 0.1 0.00082 18.8 0.1 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 ETO15386.1 - 0.0067 16.1 0.1 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain IncA PF04156.9 ETO15387.1 - 0.039 13.5 7.4 0.069 12.7 5.1 1.3 1 0 0 1 1 1 0 IncA protein Gag_p17 PF00540.13 ETO15387.1 - 0.069 12.9 1.8 0.11 12.2 1.2 1.4 1 0 0 1 1 1 0 gag gene protein p17 (matrix protein) Fib_alpha PF08702.5 ETO15387.1 - 1.2 9.2 22.6 0.36 10.9 4.2 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family BBS2_N PF14781.1 ETO15387.1 - 1.5 8.4 5.4 0.64 9.6 2.3 1.5 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal LMBR1 PF04791.11 ETO15387.1 - 3.6 6.0 8.1 5.1 5.5 5.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DASH_Dam1 PF08653.5 ETO15387.1 - 4.3 7.1 6.6 4.4 7.1 1.0 2.7 2 1 0 2 2 2 0 DASH complex subunit Dam1 FAM150 PF15129.1 ETO15387.1 - 4.7 7.1 7.4 5.7 6.8 4.4 1.7 1 1 1 2 2 2 0 FAM150 family PH PF00169.24 ETO15389.1 - 1.5e-14 54.0 0.0 1.5e-14 54.0 0.0 2.4 3 0 0 3 3 3 1 PH domain PH_11 PF15413.1 ETO15389.1 - 6e-05 23.2 0.6 6e-05 23.2 0.4 3.4 3 2 0 3 3 3 1 Pleckstrin homology domain PH_8 PF15409.1 ETO15389.1 - 0.00012 22.0 0.0 0.00012 22.0 0.0 2.2 3 0 0 3 3 3 1 Pleckstrin homology domain Tudor-knot PF11717.3 ETO15389.1 - 0.06 13.0 1.1 0.64 9.7 0.8 2.4 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain AMP-binding_C_2 PF14535.1 ETO15390.1 - 0.062 13.3 0.7 0.11 12.5 0.5 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Rota_VP2 PF05087.7 ETO15390.1 - 0.11 10.3 2.8 0.17 9.7 1.9 1.3 1 0 0 1 1 1 0 Rotavirus VP2 protein HR1 PF02185.11 ETO15391.1 - 0.0015 18.2 3.5 0.0059 16.3 2.4 2.1 1 0 0 1 1 1 1 Hr1 repeat UCH PF00443.24 ETO15392.1 - 0.0033 16.5 0.2 0.0033 16.5 0.2 2.4 1 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF2390 PF09523.5 ETO15393.1 - 0.018 15.2 1.7 0.055 13.6 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2390) TORC_N PF12884.2 ETO15393.1 - 0.043 14.3 1.7 0.069 13.6 0.1 2.1 2 0 0 2 2 2 0 Transducer of regulated CREB activity, N terminus BPL_N PF09825.4 ETO15393.1 - 2.1 7.0 7.0 2.4 6.8 4.9 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Lectin_N PF03954.9 ETO15394.1 - 0.017 14.5 7.8 0.43 9.9 3.8 2.6 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain BLOC1_2 PF10046.4 ETO15394.1 - 0.71 10.0 14.2 0.84 9.8 0.6 3.2 3 2 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Lipoprotein_6 PF01441.14 ETO15394.1 - 4 7.2 14.9 0.33 10.7 1.4 3.1 2 1 0 3 3 3 0 Lipoprotein HSP70 PF00012.15 ETO15394.1 - 4.4 5.0 14.6 0.26 9.1 4.6 2.0 2 0 0 2 2 2 0 Hsp70 protein Med4 PF10018.4 ETO15394.1 - 6.5 6.1 16.4 3 7.2 3.9 2.7 1 1 2 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 zf-RanBP PF00641.13 ETO15395.1 - 0.0099 14.9 9.0 0.019 14.0 6.2 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others TetR_C_8 PF14278.1 ETO15395.1 - 0.27 11.6 2.1 27 5.2 0.1 3.4 4 0 0 4 4 4 0 Transcriptional regulator C-terminal region DUF1336 PF07059.7 ETO15396.1 - 2.2e-33 115.5 0.5 2.2e-25 89.4 0.0 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF1336) DUF4471 PF14740.1 ETO15397.1 - 1.3e-29 103.3 2.4 1.3e-29 103.3 1.6 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4471) Bestrophin PF01062.16 ETO15397.1 - 0.093 11.6 1.7 0.2 10.5 1.2 1.6 1 1 1 2 2 2 0 Bestrophin, RFP-TM, chloride channel Penicillinase_R PF03965.11 ETO15397.1 - 0.15 12.1 1.3 0.25 11.4 0.8 1.4 1 1 0 1 1 1 0 Penicillinase repressor LAGLIDADG_1 PF00961.14 ETO15397.1 - 0.43 11.1 6.9 0.57 10.7 1.2 2.3 1 1 1 2 2 2 0 LAGLIDADG endonuclease UvrD-helicase PF00580.16 ETO15397.1 - 0.5 9.6 3.1 1.7 7.8 2.2 1.7 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain NTP_transf_2 PF01909.18 ETO15398.1 - 7.4e-06 26.2 0.0 1.4e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF294 PF03445.8 ETO15398.1 - 0.015 14.9 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Putative nucleotidyltransferase DUF294 PAP_assoc PF03828.14 ETO15398.1 - 0.018 14.9 2.3 0.049 13.5 1.6 1.8 1 0 0 1 1 1 0 Cid1 family poly A polymerase IBV_3B PF03622.8 ETO15398.1 - 0.076 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 IBV 3B protein Nuc-transf PF10127.4 ETO15398.1 - 0.11 11.7 0.0 0.33 10.2 0.0 1.8 2 0 0 2 2 2 0 Predicted nucleotidyltransferase G-alpha PF00503.15 ETO15399.1 - 4.4e-37 127.7 9.1 6.6e-37 127.1 6.3 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO15399.1 - 4.1e-07 29.4 0.1 0.00024 20.3 0.1 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family AAA_28 PF13521.1 ETO15399.1 - 0.002 18.1 0.7 0.0053 16.7 0.1 2.0 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 ETO15399.1 - 0.0087 16.5 0.7 0.062 13.7 0.0 2.8 2 1 1 3 3 3 1 Miro-like protein Baculo_LEF5_C PF11792.3 ETO15399.1 - 0.053 12.9 0.1 0.16 11.3 0.1 1.8 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain ABC_tran PF00005.22 ETO15399.1 - 0.064 13.5 0.2 0.18 12.1 0.0 1.9 2 1 0 2 2 2 0 ABC transporter Ground-like PF04155.13 ETO15399.1 - 0.11 12.8 2.1 0.49 10.7 1.4 2.2 1 1 0 1 1 1 0 Ground-like domain WD40 PF00400.27 ETO15401.1 - 2e-58 192.2 28.0 5e-12 45.2 0.6 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO15401.1 - 2.3e-18 65.6 10.6 1.9e-05 23.0 0.1 6.0 2 2 4 6 6 6 6 Nucleoporin Nup120/160 Spc24 PF08286.6 ETO15401.1 - 2.5 7.8 9.0 32 4.2 3.3 3.2 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 zf-TRAF PF02176.13 ETO15402.1 - 1.8e-06 28.1 1.5 1.8e-06 28.1 1.0 3.0 2 1 0 2 2 2 1 TRAF-type zinc finger RNB PF00773.14 ETO15402.1 - 0.0042 16.4 0.1 0.0046 16.2 0.1 1.2 1 0 0 1 1 1 1 RNB domain zf-C3HC4_2 PF13923.1 ETO15402.1 - 0.046 13.7 9.3 0.049 13.6 0.7 3.5 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.15 ETO15402.1 - 0.27 10.7 4.8 0.47 10.0 0.6 3.1 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger ThiS-like PF14453.1 ETO15404.1 - 0.0049 16.6 0.2 0.018 14.9 0.0 2.0 2 0 0 2 2 2 1 ThiS-like ubiquitin DUF1870 PF08965.5 ETO15404.1 - 0.029 14.0 0.1 0.044 13.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1870) Flagellin_IN PF07196.8 ETO15404.1 - 0.032 14.2 0.0 0.083 12.8 0.0 1.8 1 0 0 1 1 1 0 Flagellin hook IN motif Rhodanese PF00581.15 ETO15405.1 - 0.0027 18.0 0.0 0.0047 17.2 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Kelch_1 PF01344.20 ETO15406.1 - 3.4e-09 36.1 0.9 0.00026 20.4 0.1 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO15406.1 - 3.4e-05 23.8 0.6 0.31 11.3 0.0 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO15406.1 - 0.003 17.2 0.6 0.087 12.6 0.0 2.7 2 0 0 2 2 2 1 Galactose oxidase, central domain Vps39_1 PF10366.4 ETO15407.1 - 1.5 8.8 11.4 0.27 11.2 1.8 2.4 1 1 2 3 3 3 0 Vacuolar sorting protein 39 domain 1 Ycf1 PF05758.7 ETO15408.1 - 0.001 16.9 5.6 0.001 16.9 3.9 2.1 2 0 0 2 2 2 1 Ycf1 RNA_polI_A34 PF08208.6 ETO15408.1 - 0.0011 18.7 20.2 0.0011 18.7 14.0 2.3 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 BUD22 PF09073.5 ETO15408.1 - 0.015 14.4 38.9 0.045 12.8 11.5 2.1 2 0 0 2 2 2 0 BUD22 Zip PF02535.17 ETO15408.1 - 0.24 10.3 9.1 0.91 8.4 1.3 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter DUF106 PF01956.11 ETO15408.1 - 0.59 9.6 1.9 1.1 8.8 1.3 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF106 RR_TM4-6 PF06459.7 ETO15408.1 - 1.1 9.0 29.7 0.17 11.7 10.1 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Mitofilin PF09731.4 ETO15408.1 - 1.2 7.7 35.3 0.46 9.0 10.1 2.1 2 0 0 2 2 2 0 Mitochondrial inner membrane protein CT47 PF15623.1 ETO15408.1 - 1.3 8.6 30.3 0.66 9.6 9.1 2.4 2 0 0 2 2 2 0 Cancer/testis gene family 47 Vfa1 PF08432.5 ETO15408.1 - 4.1 7.3 41.1 0.37 10.8 16.6 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Glyco_hydro_31 PF01055.21 ETO15409.1 - 7.8e-49 166.6 7.7 1.9e-38 132.4 2.4 2.7 2 1 0 2 2 2 2 Glycosyl hydrolases family 31 Acyl-CoA_dh_1 PF00441.19 ETO15411.1 - 3.6e-37 127.7 0.1 4.6e-37 127.4 0.1 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 ETO15411.1 - 6.8e-11 41.5 0.1 1.6e-10 40.3 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 ETO15411.1 - 3.7e-10 40.1 0.0 5.1e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 ETO15411.1 - 1.6e-05 24.4 0.4 0.00012 21.6 0.3 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_dh_N PF02771.11 ETO15412.1 - 7.8e-31 106.9 0.0 1e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_ox_N PF14749.1 ETO15412.1 - 0.14 12.4 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Pox_A_type_inc PF04508.7 ETO15413.1 - 0.045 13.5 2.9 0.054 13.3 0.2 2.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Lzipper-MIP1 PF14389.1 ETO15413.1 - 0.084 12.9 3.2 0.16 12.0 2.2 1.4 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Utp14 PF04615.8 ETO15413.1 - 0.14 10.3 30.0 0.17 10.0 20.8 1.0 1 0 0 1 1 1 0 Utp14 protein IncA PF04156.9 ETO15413.1 - 0.25 10.9 4.8 0.34 10.4 3.3 1.3 1 0 0 1 1 1 0 IncA protein FAM209 PF15206.1 ETO15413.1 - 0.55 10.0 2.5 1.4 8.7 0.1 2.2 2 1 1 3 3 3 0 FAM209 family zf-C3HC4_3 PF13920.1 ETO15414.1 - 9.1e-11 41.2 16.2 9.1e-11 41.2 11.2 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO15414.1 - 2e-06 27.6 12.2 2e-06 27.6 8.5 3.3 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Pellino PF04710.9 ETO15414.1 - 0.011 14.4 1.1 0.016 13.8 0.7 1.3 1 0 0 1 1 1 0 Pellino Prok-RING_4 PF14447.1 ETO15414.1 - 0.012 15.1 4.7 0.012 15.1 3.2 3.5 3 1 0 3 3 3 0 Prokaryotic RING finger family 4 zf-met PF12874.2 ETO15415.1 - 0.0028 17.7 8.0 0.007 16.5 5.5 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 ETO15415.1 - 0.011 15.8 8.4 0.011 15.8 5.8 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PadR PF03551.9 ETO15415.1 - 0.026 14.2 0.7 0.069 12.9 0.5 1.7 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family SRP19 PF01922.12 ETO15415.1 - 0.057 13.9 1.7 0.17 12.5 1.2 1.9 1 0 0 1 1 1 0 SRP19 protein Kelch_5 PF13854.1 ETO15416.1 - 1.9e-07 30.9 0.3 0.0074 16.2 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO15416.1 - 5.7e-07 28.9 0.6 0.0048 16.4 0.1 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 ETO15416.1 - 0.00042 20.3 0.0 0.019 15.1 0.0 3.1 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO15416.1 - 0.00075 19.2 0.1 0.0056 16.4 0.0 2.6 1 1 1 2 2 2 1 Galactose oxidase, central domain Peptidase_M15_3 PF08291.6 ETO15416.1 - 0.0055 16.4 0.0 0.041 13.6 0.0 2.2 2 0 0 2 2 2 1 Peptidase M15 Kelch_2 PF07646.10 ETO15416.1 - 0.015 15.0 3.1 21 5.0 0.0 4.6 5 0 0 5 5 5 0 Kelch motif P16-Arc PF04699.9 ETO15417.1 - 0.0052 16.8 2.1 0.006 16.6 1.4 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Phage_int_SAM_5 PF13102.1 ETO15417.1 - 0.067 13.1 7.6 0.077 12.9 5.3 1.1 1 0 0 1 1 1 0 Phage integrase SAM-like domain DUF4163 PF13739.1 ETO15417.1 - 3.4 8.5 6.9 5 7.9 4.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4163) VWA_2 PF13519.1 ETO15418.1 - 2.1e-08 34.4 0.0 2.5e-08 34.2 0.0 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 ETO15418.1 - 8.5e-05 21.7 0.0 0.00011 21.4 0.0 1.1 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VWA PF00092.23 ETO15418.1 - 0.00033 20.4 0.0 0.00037 20.2 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF2201 PF09967.4 ETO15418.1 - 0.025 14.6 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 VWA-like domain (DUF2201) iPGM_N PF06415.8 ETO15418.1 - 0.086 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 BPG-independent PGAM N-terminus (iPGM_N) DSL PF01414.14 ETO15419.1 - 0.32 11.0 16.8 0.7 9.9 3.6 3.4 2 1 1 3 3 3 0 Delta serrate ligand DDRGK PF09756.4 ETO15421.1 - 6.4 6.1 20.1 10 5.5 13.9 1.3 1 0 0 1 1 1 0 DDRGK domain Daxx PF03344.10 ETO15421.1 - 9.3 4.5 21.9 11 4.3 15.2 1.1 1 0 0 1 1 1 0 Daxx Family Aldedh PF00171.17 ETO15423.1 - 3.5e-23 81.6 0.0 4.8e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ank_4 PF13637.1 ETO15424.1 - 2.8e-05 24.4 0.1 1.3 9.6 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO15424.1 - 0.00022 21.4 0.1 0.021 15.1 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETO15424.1 - 0.0036 17.0 0.0 2.2 8.2 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 ETO15424.1 - 0.0038 17.3 0.0 50 4.5 0.0 3.9 3 0 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.1 ETO15424.1 - 0.0096 16.1 0.0 3.7 7.9 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) WD40 PF00400.27 ETO15426.1 - 1.4e-08 34.3 5.1 3.2e-05 23.6 0.4 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat NHL PF01436.16 ETO15426.1 - 0.12 12.3 0.3 0.12 12.3 0.2 2.1 2 0 0 2 2 2 0 NHL repeat DUF1968 PF09291.5 ETO15426.1 - 0.71 9.7 5.6 1 9.2 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1968) Orthopox_A49R PF06489.6 ETO15426.1 - 0.79 9.6 5.1 0.96 9.4 3.1 1.4 1 1 0 1 1 1 0 Orthopoxvirus A49R protein RNA_polI_A34 PF08208.6 ETO15427.1 - 0.056 13.1 10.8 0.055 13.1 7.5 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF3464 PF11947.3 ETO15427.1 - 0.066 12.6 0.6 0.069 12.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) EST1_DNA_bind PF10373.4 ETO15427.1 - 0.077 12.1 3.0 0.09 11.9 2.0 1.0 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain DUF3899 PF13038.1 ETO15427.1 - 0.14 12.3 4.2 0.2 11.8 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) ATG27 PF09451.5 ETO15427.1 - 0.22 10.7 1.8 0.26 10.4 1.2 1.1 1 0 0 1 1 1 0 Autophagy-related protein 27 Peptidase_S49_N PF08496.5 ETO15427.1 - 0.96 9.2 8.9 1.1 9.0 6.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1168 PF06658.7 ETO15427.1 - 1.4 8.4 15.5 1.6 8.2 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) DUF2956 PF11169.3 ETO15427.1 - 1.8 8.5 10.7 2.3 8.2 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) SR-25 PF10500.4 ETO15427.1 - 2.9 7.3 14.9 3.4 7.0 10.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MRL1 PF13003.2 ETO15427.1 - 3 7.6 8.9 4.6 7.0 6.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L1 Cpn60_TCP1 PF00118.19 ETO15429.1 - 6e-86 288.9 0.1 6.7e-86 288.8 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1284 PF06935.6 ETO15429.1 - 0.039 14.1 0.3 0.1 12.7 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1284) Ras PF00071.17 ETO15430.1 - 0.0016 17.8 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Ras family WD40 PF00400.27 ETO15431.1 - 4.2e-61 200.7 20.2 2.2e-10 40.0 0.3 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO15431.1 - 1.9e-09 36.1 11.5 0.00017 19.8 0.5 4.7 1 1 3 4 4 4 3 Nucleoporin Nup120/160 DUF1900 PF08954.6 ETO15431.1 - 0.0039 16.7 0.6 2.3 7.7 0.0 3.8 4 1 0 4 4 4 1 Domain of unknown function (DUF1900) Lebercilin PF15619.1 ETO15431.1 - 0.012 15.0 10.2 0.012 15.0 7.1 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease HAD PF12710.2 ETO15431.1 - 0.06 13.5 3.7 17 5.5 2.2 3.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase UPF0118 PF01594.11 ETO15431.1 - 0.56 9.1 1.6 0.83 8.5 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF20 DUF4140 PF13600.1 ETO15431.1 - 2.9 8.4 8.2 4.3 7.8 1.3 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF2681 PF10883.3 ETO15431.1 - 3.8 7.7 17.2 0.16 12.2 3.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Tnp_P_element PF12017.3 ETO15431.1 - 7.3 5.7 13.8 5.1 6.2 4.0 2.3 2 0 0 2 2 2 0 Transposase protein zf-C3HC4_2 PF13923.1 ETO15432.1 - 0.021 14.8 2.6 0.23 11.5 1.8 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO15432.1 - 0.79 9.4 6.4 6.9 6.4 1.3 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 ETO15432.1 - 1.1 9.2 4.1 0.64 9.9 0.4 2.4 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING Methyltransf_28 PF02636.12 ETO15433.1 - 1.5e-15 57.2 0.0 1.7e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MRP PF09387.5 ETO15433.1 - 0.072 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial RNA binding protein MRP WD40 PF00400.27 ETO15434.1 - 2.8e-09 36.5 0.0 4.5e-06 26.3 0.0 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat VRP3 PF03536.10 ETO15434.1 - 0.0028 16.8 0.4 0.0037 16.4 0.3 1.2 1 0 0 1 1 1 1 Salmonella virulence-associated 28kDa protein FTSW_RODA_SPOVE PF01098.14 ETO15435.1 - 0.025 13.3 0.0 0.037 12.8 0.0 1.2 1 0 0 1 1 1 0 Cell cycle protein Pkinase PF00069.20 ETO15439.1 - 3.7e-35 121.3 1.9 3.7e-35 121.3 1.3 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO15439.1 - 3.1e-22 78.9 3.3 2.3e-21 76.0 2.3 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO15439.1 - 0.00078 18.5 1.2 0.0023 17.0 0.8 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Baculo_PEP_C PF04513.7 ETO15440.1 - 0.074 12.8 6.5 0.12 12.1 4.5 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG5 PF10392.4 ETO15440.1 - 0.27 11.2 10.5 0.59 10.0 7.3 1.6 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DegT_DnrJ_EryC1 PF01041.12 ETO15440.1 - 0.29 10.1 7.6 0.43 9.5 3.6 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Lectin_N PF03954.9 ETO15440.1 - 0.77 9.1 7.8 1.9 7.9 5.4 1.7 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Phage_GPO PF05929.6 ETO15440.1 - 6.1 6.0 17.0 11 5.2 11.8 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Bac_small_YrzI PF09501.5 ETO15442.1 - 5.5e-05 22.9 5.1 5.5e-05 22.9 3.6 3.3 2 1 1 3 3 3 1 Probable sporulation protein (Bac_small_yrzI) BEX PF04538.7 ETO15442.1 - 0.086 13.0 16.9 0.037 14.2 6.4 2.9 1 1 1 2 2 2 0 Brain expressed X-linked like family DUF3552 PF12072.3 ETO15442.1 - 0.47 9.6 29.3 0.37 9.9 18.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF883 PF05957.8 ETO15442.1 - 0.56 10.6 2.4 1.7 9.1 1.5 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) GOLD_2 PF13897.1 ETO15443.1 - 0.15 12.2 3.2 0.37 11.0 2.2 1.7 1 1 0 1 1 1 0 Golgi-dynamics membrane-trafficking Sec62 PF03839.11 ETO15443.1 - 3.1 7.1 5.9 4.8 6.5 4.1 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 CDC45 PF02724.9 ETO15443.1 - 3.5 5.5 11.0 4.6 5.1 7.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Kelch_6 PF13964.1 ETO15444.1 - 1.4e-05 25.0 2.3 3 8.1 0.0 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 ETO15444.1 - 4.8e-05 22.8 2.7 0.16 11.5 0.0 4.3 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 ETO15444.1 - 0.0028 17.5 2.0 3.6 7.6 0.0 3.9 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO15444.1 - 0.004 16.8 1.0 13 5.7 0.0 4.2 4 0 0 4 4 4 1 Kelch motif Peptidase_M19 PF01244.16 ETO15445.1 - 0.0014 17.6 0.6 0.0019 17.2 0.4 1.2 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) UPF0180 PF03698.8 ETO15445.1 - 0.0082 15.9 1.0 0.029 14.2 0.4 2.2 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0180) AdoHcyase_NAD PF00670.16 ETO15446.1 - 2.9e-28 98.7 2.0 1.1e-26 93.5 0.3 2.4 1 1 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AdoHcyase PF05221.12 ETO15446.1 - 8.6e-09 34.7 0.0 1.2e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase TrkA_N PF02254.13 ETO15446.1 - 0.036 14.0 0.0 0.08 12.9 0.0 1.6 2 0 0 2 2 2 0 TrkA-N domain IlvN PF07991.7 ETO15446.1 - 0.036 13.4 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_7 PF13241.1 ETO15446.1 - 0.087 13.0 0.0 0.17 12.1 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding RVT_1 PF00078.22 ETO15447.1 - 6.3e-13 48.5 0.1 7e-13 48.4 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Invas_SpaK PF03519.9 ETO15447.1 - 0.19 11.5 1.1 0.35 10.7 0.7 1.6 1 1 0 1 1 1 0 Invasion protein B family DUF2247 PF10004.4 ETO15448.1 - 0.011 15.4 0.6 0.014 15.0 0.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) AHS1 PF02682.11 ETO15448.1 - 0.024 14.0 0.0 0.028 13.8 0.0 1.1 1 0 0 1 1 1 0 Allophanate hydrolase subunit 1 SICA_beta PF12878.2 ETO15448.1 - 0.049 13.4 2.4 0.064 13.0 1.7 1.3 1 1 0 1 1 1 0 SICA extracellular beta domain CAF1 PF04857.15 ETO15448.1 - 0.049 12.9 1.5 0.057 12.7 1.1 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease DUF808 PF05661.7 ETO15448.1 - 0.83 8.4 2.9 1.1 8.0 1.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF808) Draxin PF15550.1 ETO15449.1 - 0.021 14.4 5.5 0.029 14.0 3.8 1.1 1 0 0 1 1 1 0 Draxin Mito_carr PF00153.22 ETO15450.1 - 1.6e-06 27.6 1.4 1 9.0 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 ETO15451.1 - 1.2e-19 69.8 0.5 6.6e-16 57.8 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Filament PF00038.16 ETO15452.1 - 4.3e-05 23.1 47.6 9.5e-05 22.0 33.0 1.6 1 0 0 1 1 1 1 Intermediate filament protein DUF3452 PF11934.3 ETO15452.1 - 3.5 6.9 9.1 0.7 9.2 0.5 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3452) WD40 PF00400.27 ETO15453.1 - 2.7e-31 106.3 9.2 2e-10 40.1 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO15453.1 - 8.4e-05 22.5 1.5 0.0046 17.0 0.3 2.7 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO15453.1 - 0.076 13.2 0.3 0.19 11.9 0.2 1.7 1 0 0 1 1 1 0 Galactose oxidase, central domain DUF4519 PF15012.1 ETO15453.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Herpes_TK_C PF08465.5 ETO15454.1 - 0.083 12.4 0.1 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Thymidine kinase from Herpesvirus C-terminal DDE_3 PF13358.1 ETO15455.1 - 4.7e-06 26.4 0.8 3.4e-05 23.6 0.6 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 ETO15455.1 - 0.0015 18.5 0.2 0.0026 17.7 0.2 1.3 1 0 0 1 1 1 1 Transposase HTH_21 PF13276.1 ETO15455.1 - 0.083 12.9 0.2 0.18 11.8 0.0 1.7 2 0 0 2 2 2 0 HTH-like domain WD40 PF00400.27 ETO15456.1 - 9e-40 133.1 16.3 3.9e-10 39.2 0.1 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO15456.1 - 2.8e-09 35.6 4.6 0.0037 15.4 0.1 4.0 1 1 2 4 4 4 4 Nucleoporin Nup120/160 TAFH PF07531.9 ETO15457.1 - 0.045 13.3 1.4 5.3 6.7 0.0 2.4 1 1 1 2 2 2 0 NHR1 homology to TAF ALMT PF11744.3 ETO15457.1 - 0.046 12.3 3.9 0.055 12.1 2.7 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2492 PF10678.4 ETO15457.1 - 0.046 13.8 0.3 0.32 11.0 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2492) PBP_dimer PF03717.10 ETO15457.1 - 0.12 12.4 2.8 0.15 12.0 1.9 1.3 1 0 0 1 1 1 0 Penicillin-binding Protein dimerisation domain AAA_23 PF13476.1 ETO15457.1 - 0.26 11.5 11.7 0.32 11.3 8.1 1.1 1 0 0 1 1 1 0 AAA domain Ribosomal_S20p PF01649.13 ETO15457.1 - 1.5 9.2 7.7 6.9 7.1 5.4 2.0 1 1 0 1 1 1 0 Ribosomal protein S20 Kelch_1 PF01344.20 ETO15458.1 - 5.2e-09 35.5 6.8 3e-06 26.6 0.6 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO15458.1 - 9.3e-06 25.6 6.6 0.09 12.9 0.3 4.8 4 1 1 5 5 5 2 Kelch motif Kelch_5 PF13854.1 ETO15458.1 - 5.5e-05 23.0 5.1 0.092 12.7 0.4 5.2 6 0 0 6 6 6 1 Kelch motif Kelch_3 PF13415.1 ETO15458.1 - 0.00072 19.6 4.4 0.011 15.8 0.0 3.9 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO15458.1 - 0.00089 18.9 3.5 2.6 7.8 0.1 4.1 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO15458.1 - 0.0015 18.2 6.8 1.7 8.5 0.4 4.9 5 1 0 5 5 5 2 Kelch motif PAP2_C PF14360.1 ETO15460.1 - 0.0011 19.2 0.2 0.0011 19.2 0.2 3.0 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.16 ETO15460.1 - 0.028 14.1 0.3 0.028 14.1 0.2 2.1 2 1 0 2 2 2 0 PAP2 superfamily WD40 PF00400.27 ETO15461.1 - 8.9e-74 240.9 13.4 2.1e-12 46.3 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO15461.1 - 1.2e-05 23.8 0.7 0.011 14.0 0.0 3.1 1 1 2 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO15461.1 - 0.00045 19.0 8.1 0.1 11.3 0.2 4.6 1 1 1 2 2 2 2 Nup133 N terminal like Mid2 PF04478.7 ETO15461.1 - 0.0012 18.2 0.2 15 4.9 0.0 3.7 3 0 0 3 3 3 1 Mid2 like cell wall stress sensor TPR_1 PF00515.23 ETO15461.1 - 0.0065 16.0 0.1 0.014 15.0 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO15461.1 - 0.089 12.6 0.3 0.23 11.2 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETO15461.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat PD40 PF07676.7 ETO15461.1 - 0.13 11.9 11.6 5.4 6.7 0.0 5.5 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 ETO15461.1 - 1.2 8.4 8.6 9.5 5.6 0.0 4.1 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature DUF904 PF06005.7 ETO15462.1 - 0.29 11.4 5.0 0.086 13.1 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Guanylate_cyc PF00211.15 ETO15464.1 - 1.1e-23 83.6 0.6 1.8e-23 82.8 0.4 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF3492 PF11997.3 ETO15468.1 - 0.0024 17.4 0.8 0.0031 17.0 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3492) Cas_Csy4 PF09618.5 ETO15468.1 - 0.028 14.2 0.4 0.034 13.9 0.3 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) Kelch_4 PF13418.1 ETO15469.1 - 1.2e-07 31.3 0.1 0.00017 21.3 0.0 2.5 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO15469.1 - 2.8e-05 23.5 3.1 0.00039 19.9 0.8 3.0 2 1 1 3 3 3 1 Kelch motif Kelch_6 PF13964.1 ETO15469.1 - 0.00014 21.8 1.3 0.053 13.7 0.6 2.9 1 1 1 2 2 2 2 Kelch motif Kelch_2 PF07646.10 ETO15469.1 - 0.00045 19.8 0.3 0.019 14.7 0.2 2.5 2 1 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO15469.1 - 0.0036 17.4 0.3 0.018 15.1 0.0 2.3 3 1 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO15469.1 - 0.0092 15.9 0.6 0.063 13.2 0.3 2.3 2 0 0 2 2 2 1 Kelch motif Dot_icm_IcmQ PF09475.5 ETO15471.1 - 0.019 14.2 0.2 0.044 13.0 0.0 1.6 2 0 0 2 2 2 0 Dot/Icm secretion system protein (dot_icm_IcmQ) Helicase_C_3 PF13625.1 ETO15472.1 - 1.8e-21 76.2 0.0 3.6e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETO15472.1 - 5.3e-12 45.9 0.0 2.1e-11 44.0 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 ETO15472.1 - 5.5e-11 41.8 0.4 9.8e-11 40.9 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETO15472.1 - 9.3e-11 41.4 0.0 4.2e-10 39.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETO15472.1 - 9.8e-08 31.6 0.0 2.2e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Laminin_G_3 PF13385.1 ETO15473.1 - 1e-07 32.3 0.0 2.6e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF399 PF04187.8 ETO15473.1 - 0.0073 15.8 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF399 Sterile PF03015.14 ETO15477.1 - 2.9 8.1 5.1 9.5 6.5 0.1 2.5 1 1 0 2 2 2 0 Male sterility protein bZIP_2 PF07716.10 ETO15478.1 - 0.023 14.5 0.6 0.023 14.5 0.4 2.7 2 1 0 3 3 3 0 Basic region leucine zipper DUF4618 PF15397.1 ETO15478.1 - 0.042 13.1 10.3 0.43 9.8 7.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) DUF2874 PF11396.3 ETO15478.1 - 0.24 11.4 2.2 0.58 10.1 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2874) SRP_SPB PF02978.14 ETO15478.1 - 0.42 10.8 2.7 0.38 11.0 1.2 1.5 1 1 0 1 1 1 0 Signal peptide binding domain LAMTOR PF15454.1 ETO15478.1 - 0.49 10.7 3.6 6.8 7.0 0.3 2.3 2 0 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF3340 PF11818.3 ETO15478.1 - 0.53 10.2 10.4 0.59 10.0 7.2 1.1 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) APG6 PF04111.7 ETO15478.1 - 0.58 9.1 14.0 0.71 8.8 9.7 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 ETO15478.1 - 1.1 8.7 16.4 2.4 7.7 3.7 2.5 1 1 1 2 2 2 0 Septum formation initiator Takusan PF04822.8 ETO15478.1 - 1.1 9.0 9.1 2.5 7.9 6.2 1.7 1 1 0 1 1 1 0 Takusan Rootletin PF15035.1 ETO15478.1 - 1.4 8.8 10.8 1.7 8.6 7.5 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Mu-like_Pro PF10123.4 ETO15478.1 - 1.4 8.3 5.4 1.6 8.1 3.7 1.0 1 0 0 1 1 1 0 Mu-like prophage I protein TMF_TATA_bd PF12325.3 ETO15478.1 - 1.7 8.3 12.8 1 9.0 7.3 1.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Pox_A_type_inc PF04508.7 ETO15478.1 - 2.4 8.1 9.2 7.5 6.6 0.2 3.6 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat THRAP3_BCLAF1 PF15440.1 ETO15478.1 - 4.3 5.8 8.6 5.2 5.6 6.0 1.0 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Seryl_tRNA_N PF02403.17 ETO15478.1 - 5.4 7.0 17.8 2.9 7.9 4.9 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TMPIT PF07851.8 ETO15478.1 - 5.7 5.9 9.1 6.8 5.6 6.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein ABC_tran_2 PF12848.2 ETO15478.1 - 6.5 6.6 14.1 5.1 7.0 6.6 2.1 1 1 1 2 2 2 0 ABC transporter TFIIA PF03153.8 ETO15481.1 - 0.0024 17.8 58.1 0.0024 17.8 40.3 5.3 1 1 3 4 4 4 1 Transcription factor IIA, alpha/beta subunit WD40 PF00400.27 ETO15482.1 - 1.9e-17 62.4 1.6 6.1e-13 48.1 0.3 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat eIF2A PF08662.6 ETO15482.1 - 0.051 13.2 0.1 0.064 12.9 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Velvet PF11754.3 ETO15483.1 - 4.1 6.9 9.7 17 4.9 6.8 2.0 1 1 0 1 1 1 0 Velvet factor WD40 PF00400.27 ETO15486.1 - 1.8e-12 46.6 1.6 1.4e-07 31.0 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO15486.1 - 0.02 13.0 0.1 2.2 6.3 0.0 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 G-alpha PF00503.15 ETO15487.1 - 1e-54 185.7 10.4 1.7e-54 185.0 7.2 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO15487.1 - 1.5e-10 40.6 0.3 3.5e-10 39.4 0.1 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 ETO15487.1 - 0.001 19.5 0.4 0.003 18.0 0.1 1.9 2 0 0 2 2 2 1 Miro-like protein Epimerase PF01370.16 ETO15487.1 - 0.031 13.7 0.1 1.3 8.4 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Rod_C PF10493.4 ETO15488.1 - 0.0077 14.5 0.9 0.0088 14.3 0.6 1.0 1 0 0 1 1 1 1 Rough deal protein C-terminal region EcsC PF12787.2 ETO15488.1 - 0.093 12.1 2.0 0.11 11.8 1.4 1.1 1 0 0 1 1 1 0 EcsC protein family TcdB_N PF12918.2 ETO15488.1 - 0.8 9.8 5.2 1.3 9.1 0.1 2.3 1 1 1 2 2 2 0 TcdB toxin N-terminal helical domain PNK3P PF08645.6 ETO15489.1 - 4.8e-44 149.6 3.2 1.8e-43 147.7 0.5 2.8 3 1 0 3 3 3 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 ETO15489.1 - 4e-19 68.9 0.0 1.4e-18 67.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 ETO15489.1 - 8.5e-07 28.2 0.0 0.0031 16.6 0.0 2.4 1 1 1 2 2 2 2 Zeta toxin AAA_17 PF13207.1 ETO15489.1 - 0.0043 17.8 0.2 0.046 14.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETO15489.1 - 0.011 15.8 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain PGP_phosphatase PF09419.5 ETO15489.1 - 0.021 14.1 0.3 0.13 11.6 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase AAA_16 PF13191.1 ETO15489.1 - 0.068 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain PP-binding_2 PF14573.1 ETO15489.1 - 0.11 12.6 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Acyl-carrier DUF4578 PF15147.1 ETO15490.1 - 0.11 12.8 0.1 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4578) PUF PF00806.14 ETO15491.1 - 4.2e-09 35.3 0.6 0.00012 21.3 0.0 2.6 2 0 0 2 2 2 2 Pumilio-family RNA binding repeat IPP-2 PF04979.9 ETO15491.1 - 0.0047 17.1 2.3 0.0047 17.1 1.6 1.8 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) Peptidase_S10 PF00450.17 ETO15492.1 - 1.7e-59 202.0 6.0 4.8e-59 200.5 4.2 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase PLA2_inh PF02988.10 ETO15492.1 - 0.012 16.0 2.0 0.022 15.2 1.4 1.3 1 0 0 1 1 1 0 Phospholipase A2 inhibitor Borrelia_lipo_2 PF06238.6 ETO15495.1 - 0.014 15.3 5.6 0.18 11.8 1.1 2.9 2 0 0 2 2 2 0 Borrelia burgdorferi BBR25 lipoprotein Filament PF00038.16 ETO15495.1 - 0.033 13.6 40.6 0.078 12.4 23.2 2.3 2 0 0 2 2 2 0 Intermediate filament protein PGA_cap PF09587.5 ETO15495.1 - 0.13 11.6 1.4 0.17 11.1 0.1 1.8 2 0 0 2 2 2 0 Bacterial capsule synthesis protein PGA_cap Aldo_ket_red PF00248.16 ETO15498.1 - 2.1e-29 102.2 0.0 5.6e-22 77.8 0.0 2.1 2 0 0 2 2 2 2 Aldo/keto reductase family UNC-93 PF05978.11 ETO15500.1 - 1.4e-12 47.3 12.9 1.6e-12 47.2 7.6 2.1 1 1 0 1 1 1 1 Ion channel regulatory protein UNC-93 DUF4131 PF13567.1 ETO15500.1 - 0.047 13.0 0.6 0.46 9.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) TerC PF03741.11 ETO15500.1 - 0.062 12.7 0.4 0.11 11.9 0.3 1.5 1 0 0 1 1 1 0 Integral membrane protein TerC family MFS_2 PF13347.1 ETO15500.1 - 0.14 10.4 14.8 0.052 11.9 6.4 2.0 1 1 1 2 2 2 0 MFS/sugar transport protein Radical_SAM PF04055.16 ETO15501.1 - 1.6e-20 73.9 0.7 2.8e-20 73.1 0.5 1.4 1 0 0 1 1 1 1 Radical SAM superfamily CTP_transf_1 PF01148.15 ETO15502.1 - 1.4e-64 218.2 22.7 1.8e-64 217.9 15.7 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF872 PF05915.7 ETO15502.1 - 0.11 12.3 3.3 18 5.2 2.3 2.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) DUF2628 PF10947.3 ETO15502.1 - 0.13 12.0 0.2 0.13 12.0 0.1 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2628) Lipase_3 PF01764.20 ETO15503.1 - 1.9e-11 43.7 0.0 4.4e-11 42.5 0.0 1.6 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 ETO15503.1 - 0.00044 19.6 0.0 0.0014 18.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) PGAP1 PF07819.8 ETO15503.1 - 0.00087 18.9 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 ETO15503.1 - 0.002 18.0 0.0 0.0072 16.2 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETO15503.1 - 0.0072 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 ETO15503.1 - 0.013 14.9 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DUF676 PF05057.9 ETO15503.1 - 0.043 13.0 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) UPF0227 PF05728.7 ETO15503.1 - 0.05 13.3 0.2 0.56 9.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Thioesterase PF00975.15 ETO15503.1 - 0.067 13.3 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Fer4_8 PF13183.1 ETO15504.1 - 0.039 13.9 0.4 0.039 13.9 0.3 2.2 2 1 0 2 2 2 0 4Fe-4S dicluster domain eRF1_3 PF03465.10 ETO15505.1 - 0.0013 18.9 0.2 0.028 14.6 0.2 2.4 1 1 0 1 1 1 1 eRF1 domain 3 DUF4271 PF14093.1 ETO15505.1 - 0.0029 17.3 0.6 0.0042 16.7 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4271) M11L PF11099.3 ETO15505.1 - 0.14 11.8 1.7 0.99 9.1 0.1 2.2 1 1 0 2 2 2 0 Apoptosis regulator M11L like NIF PF03031.13 ETO15506.1 - 4e-22 78.5 0.1 6.4e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Pex14_N PF04695.8 ETO15506.1 - 0.0019 18.2 4.3 0.002 18.1 3.0 1.2 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Hydantoinase_A PF01968.13 ETO15506.1 - 0.1 11.6 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase RbsD_FucU PF05025.8 ETO15506.1 - 0.21 11.8 4.1 0.41 10.9 0.0 2.1 2 0 0 2 2 2 0 RbsD / FucU transport protein family AIF_C PF14721.1 ETO15506.1 - 0.69 10.1 3.4 0.97 9.6 2.3 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term TFIIA PF03153.8 ETO15506.1 - 4 7.2 15.2 4.4 7.0 10.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit JAB PF01398.16 ETO15507.1 - 4.5e-12 45.7 1.6 1.1e-11 44.4 0.1 2.4 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 ETO15507.1 - 3.6e-11 42.5 1.1 9.2e-11 41.2 0.8 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Myb_DNA-binding PF00249.26 ETO15507.1 - 8.2e-09 35.3 0.0 1.8e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 ETO15507.1 - 0.00044 20.3 0.1 0.0018 18.3 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain UPF0172 PF03665.8 ETO15507.1 - 0.016 14.6 0.3 0.016 14.6 0.2 2.6 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0172) Baculo_ODV-E27 PF05314.6 ETO15509.1 - 0.054 12.5 0.8 6.8 5.6 0.3 2.1 2 0 0 2 2 2 0 Baculovirus occlusion-derived virus envelope protein EC27 BsuBI_PstI_RE PF06616.6 ETO15509.1 - 0.074 11.8 0.4 0.21 10.3 0.2 1.8 1 1 1 2 2 2 0 BsuBI/PstI restriction endonuclease C-terminus WD40 PF00400.27 ETO15510.1 - 2.4e-30 103.2 4.3 7.5e-12 44.6 0.1 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO15510.1 - 0.00037 18.7 0.4 1.5 6.8 0.0 3.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 LRRC37AB_C PF14914.1 ETO15510.1 - 0.049 13.0 0.6 0.074 12.4 0.4 1.2 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain TPR_12 PF13424.1 ETO15512.1 - 1.3e-69 230.0 13.9 3.2e-21 75.0 0.6 4.6 2 2 2 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETO15512.1 - 6.9e-43 143.3 0.1 3.9e-09 36.1 0.1 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETO15512.1 - 8e-38 126.5 30.0 5.2e-08 32.1 0.0 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.1 ETO15512.1 - 1.4e-37 127.1 11.3 4.9e-11 42.1 1.5 4.4 3 1 1 4 4 4 4 TPR repeat TPR_8 PF13181.1 ETO15512.1 - 1.3e-29 99.7 27.4 1.7e-05 24.2 0.7 7.1 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 ETO15512.1 - 2.1e-29 99.0 21.9 6.4e-06 25.6 0.3 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.1 ETO15512.1 - 1e-27 93.7 7.3 2.1e-05 23.9 0.0 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 ETO15512.1 - 1.2e-11 43.8 10.0 0.093 12.9 0.1 6.9 6 2 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO15512.1 - 4.3e-10 39.3 0.0 2.9 8.7 0.0 6.9 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO15512.1 - 3e-09 37.3 1.4 0.02 15.5 0.0 4.4 2 2 2 4 4 4 3 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO15512.1 - 3.1e-08 32.7 2.2 0.13 11.5 0.1 5.9 6 0 0 6 6 6 2 SHNi-TPR TPR_6 PF13174.1 ETO15512.1 - 6.3e-08 32.5 8.3 9.9 6.8 0.0 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat MIT PF04212.13 ETO15512.1 - 9.1e-07 28.6 14.4 0.81 9.6 0.0 6.5 7 0 0 7 7 7 2 MIT (microtubule interacting and transport) domain DUF2225 PF09986.4 ETO15512.1 - 1.2e-05 24.9 7.7 0.27 10.6 0.3 3.4 2 1 0 3 3 3 3 Uncharacterized protein conserved in bacteria (DUF2225) Apc3 PF12895.2 ETO15512.1 - 0.00065 19.7 14.6 0.099 12.7 0.3 4.0 2 2 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF627 PF04781.7 ETO15512.1 - 0.0034 16.9 4.1 0.046 13.3 0.1 3.2 4 0 0 4 4 4 1 Protein of unknown function (DUF627) DUF3856 PF12968.2 ETO15512.1 - 0.011 15.5 3.6 4.3 7.1 0.0 4.3 2 2 2 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_3 PF07720.7 ETO15512.1 - 0.048 13.4 14.8 2.8 7.8 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Sel1 PF08238.7 ETO15512.1 - 3.9 8.2 6.8 32 5.3 0.1 4.2 4 0 0 4 4 3 0 Sel1 repeat UFD1 PF03152.9 ETO15515.1 - 7.8e-40 135.8 0.0 8.5e-40 135.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 WD40 PF00400.27 ETO15519.1 - 5.2e-56 184.6 22.2 1.3e-12 47.0 0.1 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO15519.1 - 1.1e-12 46.8 6.1 0.0063 14.7 0.0 5.3 1 1 3 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO15519.1 - 0.0027 16.5 16.3 0.16 10.6 2.8 4.2 1 1 3 4 4 4 3 Nup133 N terminal like USP7_C2 PF14533.1 ETO15519.1 - 0.091 12.1 0.9 4.7 6.5 0.0 3.1 2 1 0 3 3 3 0 Ubiquitin-specific protease C-terminal PQQ_2 PF13360.1 ETO15519.1 - 0.093 12.1 0.1 6.3 6.1 0.0 3.0 3 1 0 3 3 3 0 PQQ-like domain Exo_endo_phos_2 PF14529.1 ETO15520.1 - 2.4e-05 23.9 0.3 0.014 15.0 0.1 2.6 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase DUF1349 PF07081.6 ETO15521.1 - 1.1e-40 139.0 0.0 3.1e-38 130.9 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) DUF1561 PF07598.6 ETO15521.1 - 0.02 12.8 0.8 0.024 12.6 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1561) RR_TM4-6 PF06459.7 ETO15522.1 - 0.14 12.0 18.5 0.32 10.8 12.8 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4407 PF14362.1 ETO15522.1 - 0.77 8.6 10.4 1.3 7.9 7.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4175 PF13779.1 ETO15522.1 - 8.4 3.9 32.3 12 3.3 22.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Bud13 PF09736.4 ETO15523.1 - 0.25 11.6 12.4 0.32 11.2 8.6 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Presenilin PF01080.12 ETO15523.1 - 3.8 6.2 5.1 4.6 5.9 3.5 1.2 1 0 0 1 1 1 0 Presenilin DUF1717 PF05414.6 ETO15526.1 - 0.13 12.7 1.9 1.3 9.5 0.3 2.3 1 1 1 2 2 2 0 Viral domain of unknown function (DUF1717) CAP_GLY PF01302.20 ETO15527.1 - 0.036 13.7 0.0 0.082 12.6 0.0 1.6 1 0 0 1 1 1 0 CAP-Gly domain Pkinase PF00069.20 ETO15528.1 - 0.0013 17.8 0.0 0.0027 16.8 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase PF00069.20 ETO15529.1 - 4.4e-53 180.0 0.2 5.2e-53 179.8 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO15529.1 - 2e-35 122.1 0.1 2.4e-35 121.8 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO15529.1 - 5.1e-07 28.9 0.0 8.9e-07 28.1 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETO15529.1 - 2.9e-06 26.4 0.2 4.9e-06 25.7 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO15529.1 - 0.00014 21.7 0.1 0.00019 21.2 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 ETO15529.1 - 0.0017 17.9 0.3 0.0035 16.9 0.2 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 ETO15529.1 - 0.0024 17.2 0.2 0.003 16.9 0.2 1.1 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 ETO15529.1 - 0.0033 16.0 0.1 0.0043 15.6 0.1 1.1 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC YrbL-PhoP_reg PF10707.4 ETO15529.1 - 0.0059 15.9 0.0 0.0091 15.3 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kelch_1 PF01344.20 ETO15531.1 - 3e-11 42.6 7.6 7.9e-09 34.9 0.1 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO15531.1 - 1.6e-08 34.3 7.1 0.016 15.3 0.1 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 ETO15531.1 - 1.3e-05 24.8 9.2 0.00034 20.3 0.1 4.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO15531.1 - 0.00011 22.2 5.2 0.02 15.0 0.0 4.4 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO15531.1 - 0.00036 20.3 5.2 0.47 10.4 0.1 3.5 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO15531.1 - 0.0077 15.9 3.2 0.42 10.4 0.1 3.9 4 0 0 4 4 4 1 Kelch motif fn3 PF00041.16 ETO15532.1 - 0.016 15.3 1.7 0.021 14.9 0.1 2.0 2 0 0 2 2 2 0 Fibronectin type III domain Pga1 PF10333.4 ETO15532.1 - 1.6 8.3 6.7 0.87 9.2 0.3 2.5 2 1 1 3 3 3 0 GPI-Mannosyltransferase II co-activator WD40 PF00400.27 ETO15533.1 - 5.8e-57 187.6 17.9 2.7e-11 42.8 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO15533.1 - 7.6e-16 57.3 4.7 0.016 13.3 0.1 6.2 2 1 3 6 6 6 5 Nucleoporin Nup120/160 HAD PF12710.2 ETO15533.1 - 0.052 13.7 2.4 3.2 7.8 1.6 2.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase ABC_tran PF00005.22 ETO15534.1 - 3.2e-17 63.1 0.0 5.2e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 ETO15534.1 - 2e-07 31.2 0.0 2.3e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 ETO15534.1 - 0.001 18.9 0.2 0.013 15.3 0.1 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 ETO15534.1 - 0.0014 17.8 0.0 0.0017 17.6 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF1341 PF07071.6 ETO15534.1 - 0.089 12.3 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1341) WD40 PF00400.27 ETO15535.1 - 2.7e-22 77.7 5.3 4.5e-09 35.8 0.2 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat eIF2A PF08662.6 ETO15535.1 - 2.6e-09 37.0 0.6 8.3e-05 22.3 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO15535.1 - 6.4e-05 21.2 1.8 0.023 12.8 0.0 3.0 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO15535.1 - 0.00082 18.2 6.9 0.0037 16.0 0.2 2.1 2 0 0 2 2 2 2 Nup133 N terminal like Proteasome_A_N PF10584.4 ETO15535.1 - 0.024 13.9 0.0 4.8 6.5 0.0 2.6 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature PD40 PF07676.7 ETO15535.1 - 0.026 14.1 0.3 8.7 6.1 0.0 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat B_lectin PF01453.19 ETO15535.1 - 0.08 12.8 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 D-mannose binding lectin GSDH PF07995.6 ETO15535.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Glucose / Sorbosone dehydrogenase DUF2963 PF11178.3 ETO15535.1 - 0.94 8.9 5.0 5.6 6.4 0.7 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2963) WD40 PF00400.27 ETO15537.1 - 6.7e-10 38.4 2.1 1.3e-09 37.5 0.0 2.4 3 0 0 3 3 3 1 WD domain, G-beta repeat FG-GAP PF01839.18 ETO15538.1 - 2.9e-06 26.8 4.8 0.0019 17.8 0.0 3.4 3 0 0 3 3 3 2 FG-GAP repeat FG-GAP_2 PF14312.1 ETO15538.1 - 0.004 17.1 0.0 0.23 11.5 0.0 2.8 2 0 0 2 2 2 1 FG-GAP repeat TcdB_toxin_midN PF12256.3 ETO15538.1 - 0.01 15.3 0.0 1.3 8.3 0.0 2.4 2 0 0 2 2 2 0 Insecticide toxin TcdB middle/N-terminal region VCBS PF13517.1 ETO15538.1 - 0.012 15.9 12.5 0.11 12.8 0.1 3.6 2 1 2 4 4 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella RCR PF12273.3 ETO15539.1 - 7.9e-05 23.2 5.8 0.00013 22.5 4.0 1.5 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Neur_chan_memb PF02932.11 ETO15539.1 - 0.00068 19.6 6.3 0.00095 19.1 4.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region SprA-related PF12118.3 ETO15539.1 - 0.0016 17.8 18.7 0.0019 17.5 13.0 1.2 1 0 0 1 1 1 1 SprA-related family SID-1_RNA_chan PF13965.1 ETO15539.1 - 0.045 11.9 7.0 0.025 12.7 3.8 1.3 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 Hid1 PF12722.2 ETO15539.1 - 0.08 10.6 19.6 0.1 10.2 13.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2215 PF10225.4 ETO15539.1 - 0.28 10.5 6.3 0.39 10.1 4.3 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Mem_trans PF03547.13 ETO15539.1 - 0.28 9.4 2.8 0.36 9.0 1.9 1.3 1 0 0 1 1 1 0 Membrane transport protein DUF4106 PF13388.1 ETO15539.1 - 0.8 8.6 16.9 1.1 8.2 11.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) PAT1 PF09770.4 ETO15539.1 - 1 7.4 24.9 1.3 7.1 17.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Herpes_LMP2 PF07415.6 ETO15539.1 - 2.3 6.7 7.7 3.2 6.2 5.4 1.3 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein DUF913 PF06025.7 ETO15539.1 - 4 6.0 9.9 5.1 5.7 6.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Gag_spuma PF03276.9 ETO15539.1 - 5.3 5.2 17.6 6.3 4.9 12.2 1.2 1 0 0 1 1 1 0 Spumavirus gag protein TMEM51 PF15345.1 ETO15539.1 - 5.6 6.5 15.3 8.1 6.0 10.6 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 ORC6 PF05460.8 ETO15539.1 - 7.4 5.5 19.7 9.7 5.1 13.6 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Cwf_Cwc_15 PF04889.7 ETO15539.1 - 7.7 6.1 31.6 11 5.6 21.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sec20 PF03908.8 ETO15540.1 - 0.0039 16.8 3.5 0.005 16.5 2.4 1.1 1 0 0 1 1 1 1 Sec20 FKBP_N PF01346.13 ETO15540.1 - 0.023 14.7 0.3 0.028 14.4 0.2 1.1 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Utp11 PF03998.8 ETO15540.1 - 0.027 14.3 0.1 0.028 14.2 0.0 1.1 1 0 0 1 1 1 0 Utp11 protein Pex24p PF06398.6 ETO15540.1 - 0.038 12.7 1.2 0.042 12.6 0.9 1.0 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Kelch_6 PF13964.1 ETO15541.1 - 0.00028 20.9 2.7 0.012 15.7 0.0 2.9 3 1 0 3 3 3 1 Kelch motif Kelch_1 PF01344.20 ETO15541.1 - 0.011 15.2 3.6 0.1 12.1 0.0 3.4 3 1 0 3 3 3 0 Kelch motif Kelch_5 PF13854.1 ETO15541.1 - 0.028 14.3 0.2 7.4 6.6 0.0 2.7 2 0 0 2 2 2 0 Kelch motif UPF0075 PF03702.9 ETO15541.1 - 0.054 12.3 0.6 0.28 10.0 0.0 2.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0075) Kelch_2 PF07646.10 ETO15541.1 - 0.14 12.0 0.3 3.1 7.7 0.0 3.0 3 1 0 3 3 3 0 Kelch motif Peptidase_C14 PF00656.17 ETO15543.1 - 4e-05 23.4 2.9 0.00064 19.4 2.0 2.3 1 1 0 1 1 1 1 Caspase domain Kelch_2 PF07646.10 ETO15543.1 - 0.00017 21.2 2.3 0.0091 15.7 0.1 4.0 4 1 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 ETO15543.1 - 0.00045 20.1 1.8 0.24 11.3 0.2 4.0 3 1 1 4 4 4 1 Kelch motif Kelch_6 PF13964.1 ETO15543.1 - 0.00088 19.3 1.4 0.019 15.1 0.1 3.8 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO15543.1 - 0.0054 16.4 0.2 0.19 11.5 0.0 3.1 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO15543.1 - 0.041 13.4 3.1 0.057 12.9 0.1 2.7 3 0 0 3 3 3 0 Kelch motif WD40 PF00400.27 ETO15544.1 - 1.5e-56 186.3 23.7 1.5e-11 43.7 0.4 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO15544.1 - 3.3e-11 42.0 1.5 0.0035 15.5 0.1 4.1 2 1 2 4 4 4 4 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO15544.1 - 0.052 13.3 0.9 15 5.3 0.0 3.9 2 1 2 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Pkinase PF00069.20 ETO15545.1 - 0.0002 20.6 0.8 0.00052 19.2 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain PSS PF03034.10 ETO15547.1 - 5.7e-75 252.3 20.3 1.1e-43 149.6 4.9 3.2 2 1 1 3 3 3 3 Phosphatidyl serine synthase Peptidase_M16_C PF05193.16 ETO15548.1 - 7.8e-07 28.9 0.0 9.2e-07 28.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase M16 inactive domain tRNA_deacylase PF04414.7 ETO15549.1 - 0.11 11.6 0.2 0.24 10.5 0.1 1.6 2 0 0 2 2 2 0 D-aminoacyl-tRNA deacylase WD40 PF00400.27 ETO15550.1 - 1.2e-59 196.1 31.6 7.6e-11 41.4 1.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO15550.1 - 6.1e-11 41.1 4.1 0.051 11.7 0.1 5.5 1 1 1 4 4 4 4 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO15550.1 - 0.002 18.2 7.3 1.4 9.2 0.1 4.7 4 0 0 4 4 4 2 Kelch motif Nucleoporin_N PF08801.6 ETO15550.1 - 0.01 14.5 10.1 4 6.0 1.5 4.3 1 1 1 2 2 2 0 Nup133 N terminal like DUF4221 PF13970.1 ETO15550.1 - 0.26 10.5 2.8 3.4 6.9 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4221) DUF2358 PF10184.4 ETO15551.1 - 0.051 13.5 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) DUF4326 PF14216.1 ETO15552.1 - 0.055 14.0 0.6 0.12 12.9 0.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4326) RNA_pol_Rpb1_5 PF04998.12 ETO15552.1 - 7.8 5.6 11.6 5.8 6.0 7.2 1.3 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Gemini_AL1 PF00799.15 ETO15557.1 - 6.4e-23 80.7 1.7 2.4e-22 78.9 1.2 2.0 1 0 0 1 1 1 1 Geminivirus Rep catalytic domain IstB_IS21 PF01695.12 ETO15557.1 - 0.042 13.2 1.7 0.82 9.0 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein Kelch_1 PF01344.20 ETO15558.1 - 0.00021 20.7 0.7 0.0018 17.7 0.5 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETO15558.1 - 0.0013 18.8 1.3 14 6.0 0.1 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO15558.1 - 0.011 15.9 0.1 0.036 14.2 0.0 1.9 1 0 0 1 1 1 0 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO15558.1 - 0.083 12.6 11.4 0.16 11.7 0.3 4.7 5 2 1 6 6 6 0 Kelch motif Kelch_6 PF13964.1 ETO15559.1 - 1.3e-06 28.2 8.0 0.033 14.3 0.0 4.3 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO15559.1 - 0.0006 19.2 6.0 0.004 16.6 0.1 3.2 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETO15559.1 - 0.0035 17.0 0.1 1.6 8.5 0.0 3.4 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO15559.1 - 0.01 15.8 2.8 6.8 6.7 0.0 3.9 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO15559.1 - 0.036 13.8 4.5 3.8 7.4 0.0 3.7 4 0 0 4 4 4 0 Kelch motif N_Asn_amidohyd PF14736.1 ETO15559.1 - 0.072 11.9 0.1 0.8 8.5 0.0 2.2 2 0 0 2 2 2 0 Protein N-terminal asparagine amidohydrolase WD40 PF00400.27 ETO15560.1 - 8e-56 184.0 29.0 7.7e-12 44.6 0.9 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO15560.1 - 5.5e-08 31.3 2.7 0.025 12.7 0.2 3.7 2 1 1 4 4 4 3 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO15560.1 - 0.1 12.8 13.3 1.2 9.4 0.1 5.9 6 0 0 6 6 6 0 Kelch motif WD40 PF00400.27 ETO15561.1 - 1.1e-73 240.7 16.6 1.2e-12 47.2 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO15561.1 - 2.2e-13 50.3 1.8 0.00017 21.3 0.1 3.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO15561.1 - 1.2e-10 40.2 4.2 0.048 11.7 0.1 5.1 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO15561.1 - 8.9e-06 24.7 8.8 1.4 7.6 0.2 5.2 1 1 4 5 5 5 3 Nup133 N terminal like PD40 PF07676.7 ETO15561.1 - 9.6e-06 25.1 8.1 2.7 7.7 0.1 4.9 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO15561.1 - 1.3e-05 24.7 0.1 0.0024 17.3 0.1 3.0 1 1 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO15561.1 - 0.00014 20.3 0.0 0.11 10.7 0.0 2.5 1 1 0 2 2 2 2 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO15561.1 - 0.0013 17.8 1.3 1.6 7.7 0.0 4.2 1 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Resistin PF06954.6 ETO15561.1 - 0.0057 16.9 0.3 30 4.9 0.0 3.9 2 2 1 4 4 4 0 Resistin Hira PF07569.6 ETO15561.1 - 0.013 14.7 1.4 16 4.6 0.0 4.3 2 2 3 5 5 5 0 TUP1-like enhancer of split DUF1258 PF06869.7 ETO15561.1 - 0.052 12.6 1.5 6 5.8 0.0 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF1258) PQQ_3 PF13570.1 ETO15561.1 - 0.13 12.5 0.2 34 4.9 0.0 3.6 3 1 1 4 4 4 0 PQQ-like domain Proteasome_A_N PF10584.4 ETO15561.1 - 0.41 10.0 14.2 10 5.5 0.0 5.2 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature CYTL1 PF15153.1 ETO15562.1 - 0.03 14.0 0.1 0.05 13.2 0.1 1.3 1 0 0 1 1 1 0 Cytokine-like protein 1 WD40 PF00400.27 ETO15563.1 - 4.8e-53 175.2 7.8 7.2e-12 44.7 0.2 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO15563.1 - 4.2e-08 31.7 1.9 0.04 12.0 0.1 4.7 1 1 2 4 4 4 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO15563.1 - 0.00068 19.3 3.1 0.13 12.0 0.1 3.9 2 2 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region HARP PF07443.8 ETO15563.1 - 0.038 13.3 0.0 4.9 6.6 0.0 3.1 3 0 0 3 3 3 0 HepA-related protein (HARP) DUF851 PF05867.6 ETO15563.1 - 0.073 12.2 0.0 1.6 7.9 0.0 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF851) PurA PF04845.8 ETO15564.1 - 0.029 13.4 0.0 0.032 13.3 0.0 1.1 1 0 0 1 1 1 0 PurA ssDNA and RNA-binding protein DUF4062 PF13271.1 ETO15564.1 - 0.056 13.4 0.1 0.079 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4062) DUF4557 PF15101.1 ETO15565.1 - 0.02 14.7 5.0 0.034 13.9 3.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4557) DUF3987 PF13148.1 ETO15566.1 - 0.1 11.1 0.8 0.13 10.7 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) CAS_CSE1 PF03378.10 ETO15567.1 - 0.0075 14.6 0.2 0.009 14.3 0.2 1.1 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus YycC PF14174.1 ETO15567.1 - 0.02 14.5 0.4 0.058 13.0 0.3 1.7 1 0 0 1 1 1 0 YycC-like protein DEP PF00610.16 ETO15567.1 - 0.11 12.2 1.0 3.6 7.3 0.0 2.9 3 0 0 3 3 3 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) WD40 PF00400.27 ETO15568.1 - 4.4e-58 191.2 29.1 2.4e-13 49.4 0.1 7.5 7 2 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO15568.1 - 6.3e-10 37.8 5.0 0.0038 15.4 0.0 4.3 1 1 1 4 4 4 4 Nucleoporin Nup120/160 HAD PF12710.2 ETO15568.1 - 0.17 12.0 2.1 13 5.9 1.4 2.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase WD40 PF00400.27 ETO15569.1 - 8.5e-18 63.5 0.4 1.7e-11 43.5 0.0 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO15569.1 - 0.0013 16.9 0.2 0.043 11.9 0.0 2.1 1 1 0 2 2 2 2 Nucleoporin Nup120/160 WD40 PF00400.27 ETO15570.1 - 1.6e-20 72.1 6.4 5.2e-08 32.4 0.0 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO15570.1 - 0.00022 19.5 0.2 0.019 13.1 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Resistin PF06954.6 ETO15571.1 - 0.012 15.8 0.4 0.03 14.5 0.3 1.7 1 0 0 1 1 1 0 Resistin Git3_C PF11970.3 ETO15571.1 - 0.16 11.7 1.1 0.61 9.8 0.1 2.5 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term RRM_1 PF00076.17 ETO15572.1 - 3.5e-10 39.3 0.1 6.2e-10 38.5 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO15572.1 - 4.6e-08 32.7 1.1 6.4e-08 32.3 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO15572.1 - 3.2e-05 23.8 0.0 6.5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) YaaC PF14175.1 ETO15572.1 - 0.071 12.0 3.5 0.082 11.8 2.4 1.0 1 0 0 1 1 1 0 YaaC-like Protein EST1_DNA_bind PF10373.4 ETO15572.1 - 0.1 11.7 0.4 0.12 11.5 0.3 1.1 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain Sipho_Gp157 PF05565.6 ETO15572.1 - 4 6.9 10.3 0.4 10.2 2.5 2.0 2 0 0 2 2 2 0 Siphovirus Gp157 DUF2951 PF11166.3 ETO15572.1 - 6.7 6.6 8.9 0.9 9.4 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Pkinase PF00069.20 ETO15573.1 - 8.5e-24 84.0 1.2 3.6e-23 82.0 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO15573.1 - 1.3e-11 44.0 0.1 2.5e-11 43.1 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO15573.1 - 0.007 15.3 0.0 0.0092 14.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Uso1_p115_C PF04871.8 ETO15573.1 - 0.021 14.7 11.2 0.081 12.8 7.3 2.1 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Relaxase PF03432.9 ETO15573.1 - 0.15 11.4 3.4 0.21 10.9 2.4 1.2 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain Seryl_tRNA_N PF02403.17 ETO15573.1 - 0.34 10.9 7.7 0.63 10.0 5.4 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.1 ETO15573.1 - 0.39 9.6 3.8 0.51 9.2 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CcdA PF07362.7 ETO15573.1 - 0.68 9.8 4.0 1.7 8.5 2.7 1.6 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA IncA PF04156.9 ETO15573.1 - 0.72 9.4 7.2 1 8.9 5.0 1.3 1 0 0 1 1 1 0 IncA protein Bap31 PF05529.7 ETO15573.1 - 1.3 8.4 7.5 1.9 7.8 5.2 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF342 PF03961.8 ETO15573.1 - 2.2 6.5 5.8 2.7 6.2 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) P30 PF07390.6 ETO15574.1 - 0.024 14.1 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 Mycoplasma P30 protein PSII PF00421.14 ETO15577.1 - 0.0079 14.8 0.0 0.013 14.1 0.0 1.3 1 0 0 1 1 1 1 Photosystem II protein Neur_chan_memb PF02932.11 ETO15577.1 - 7.4 6.3 7.8 16 5.3 5.4 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EF-hand_1 PF00036.27 ETO15579.1 - 6.9e-07 28.1 0.1 1.1e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 ETO15579.1 - 1.5e-05 24.5 0.7 0.00033 20.2 0.1 2.2 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 ETO15579.1 - 2.5e-05 23.3 0.1 4.2e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 ETO15579.1 - 6.2e-05 22.5 0.1 0.00012 21.6 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 ETO15579.1 - 0.00015 21.7 0.1 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 ETO15580.1 - 0.00066 18.9 0.4 0.0017 17.5 0.3 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 ETO15580.1 - 0.0014 18.6 0.1 0.0022 18.0 0.0 1.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO15580.1 - 0.06 12.6 0.6 0.19 11.1 0.4 1.9 1 0 0 1 1 1 0 EF hand YMF19 PF02326.10 ETO15580.1 - 0.15 12.6 10.7 0.11 13.1 5.5 2.1 2 0 0 2 2 2 0 Plant ATP synthase F0 Pex2_Pex12 PF04757.9 ETO15580.1 - 0.45 9.8 2.9 0.69 9.2 2.0 1.2 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region SHOCT PF09851.4 ETO15580.1 - 0.57 9.7 0.1 0.57 9.7 0.1 2.6 3 0 0 3 3 3 0 Short C-terminal domain TraG_N PF07916.6 ETO15580.1 - 5.2 5.3 7.3 6.7 5.0 5.0 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Kelch_6 PF13964.1 ETO15581.1 - 1.7e-09 37.3 3.2 0.00099 19.1 0.0 4.3 3 1 1 4 4 4 3 Kelch motif Kelch_5 PF13854.1 ETO15581.1 - 6.9e-05 22.7 6.0 0.28 11.1 0.0 4.6 4 1 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO15581.1 - 0.00096 18.6 14.3 0.096 12.2 0.0 4.7 5 1 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 ETO15581.1 - 0.88 9.8 9.0 38 4.5 0.0 5.0 4 2 0 4 4 4 0 Galactose oxidase, central domain zf-TRAF PF02176.13 ETO15582.1 - 9.9e-08 32.2 5.6 9.9e-08 32.2 3.9 3.3 2 1 1 3 3 3 1 TRAF-type zinc finger zf-U11-48K PF05253.7 ETO15582.1 - 0.034 13.8 1.2 1.2 8.9 0.0 3.0 2 0 0 2 2 2 0 U11-48K-like CHHC zinc finger MHC_I_C PF06623.6 ETO15583.1 - 0.14 11.6 0.4 0.22 11.0 0.3 1.3 1 0 0 1 1 1 0 MHC_I C-terminus Glyco_hydro_65m PF03632.10 ETO15584.1 - 1.1e-58 198.7 9.0 2.8e-51 174.3 0.4 3.3 2 1 1 3 3 3 3 Glycosyl hydrolase family 65 central catalytic domain RNase_H PF00075.19 ETO15585.1 - 3.5e-10 40.3 1.5 1.1e-09 38.7 0.2 2.0 1 1 1 2 2 2 1 RNase H DUF3450 PF11932.3 ETO15586.1 - 0.071 12.3 8.0 0.1 11.8 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CpXC PF14353.1 ETO15586.1 - 0.32 10.9 7.6 0.66 9.9 5.3 1.7 1 1 0 1 1 1 0 CpXC protein IncA PF04156.9 ETO15586.1 - 7.3 6.1 7.5 11 5.5 5.2 1.2 1 0 0 1 1 1 0 IncA protein Arm PF00514.18 ETO15587.1 - 0.0025 17.5 2.1 21 5.1 0.0 4.3 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat Dala_Dala_lig_N PF01820.16 ETO15588.1 - 0.41 10.9 4.1 1.1 9.6 0.1 2.5 2 1 1 3 3 3 0 D-ala D-ala ligase N-terminus WD40 PF00400.27 ETO15589.1 - 3.9e-166 533.7 40.0 4.6e-12 45.3 0.2 16.4 16 0 0 16 16 16 16 WD domain, G-beta repeat Str_synth PF03088.11 ETO15589.1 - 2.6e-08 33.7 10.5 3.8 7.6 0.0 9.2 7 3 5 12 12 12 2 Strictosidine synthase Cytochrom_D1 PF02239.11 ETO15589.1 - 3.8e-06 25.4 11.0 0.92 7.7 0.0 6.3 2 1 3 6 6 6 4 Cytochrome D1 heme domain Mid2 PF04478.7 ETO15589.1 - 4.6e-06 26.1 15.0 3.4 7.0 0.1 8.3 5 3 3 8 8 8 2 Mid2 like cell wall stress sensor DUF1258 PF06869.7 ETO15589.1 - 1.2e-05 24.5 4.0 0.062 12.3 0.0 5.2 4 3 4 8 8 8 2 Protein of unknown function (DUF1258) Nbas_N PF15492.1 ETO15589.1 - 3.2e-05 23.1 10.1 0.8 8.7 0.0 6.6 3 2 2 7 7 7 3 Neuroblastoma-amplified sequence, N terminal DPPIV_N PF00930.16 ETO15589.1 - 9.4e-05 21.1 4.3 0.78 8.2 0.0 6.2 4 4 0 6 6 6 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Pentapeptide PF00805.17 ETO15589.1 - 9.7e-05 21.5 3.5 0.00033 19.8 2.2 2.0 1 1 0 1 1 1 1 Pentapeptide repeats (8 copies) Pectate_lyase22 PF14583.1 ETO15589.1 - 0.015 13.8 0.0 2.2 6.6 0.0 3.9 3 2 1 5 5 5 0 Oligogalacturonate lyase Pentapeptide_3 PF13576.1 ETO15589.1 - 0.016 15.1 1.4 0.043 13.6 0.1 2.6 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.1 ETO15589.1 - 0.02 14.6 0.5 0.064 13.0 0.3 1.8 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) PD40 PF07676.7 ETO15589.1 - 5.5 6.7 31.2 4.9 6.9 0.0 9.9 11 0 0 11 11 11 0 WD40-like Beta Propeller Repeat Beta-lactamase PF00144.19 ETO15591.1 - 1.4e-06 27.5 0.0 4e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase ESCRT-II PF05871.7 ETO15592.1 - 1.1e-40 138.7 0.1 1.6e-40 138.2 0.1 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit HeH PF12949.2 ETO15592.1 - 0.083 12.4 0.1 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 HeH/LEM domain TRL PF13146.1 ETO15592.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 TRL-like protein family Aldedh PF00171.17 ETO15593.1 - 3.2e-149 497.1 1.3 1.9e-79 267.1 0.0 2.9 2 1 0 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.6 ETO15593.1 - 1.2e-05 24.6 0.1 3.5e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) OmdA PF13376.1 ETO15593.1 - 0.0093 15.6 0.5 0.024 14.3 0.4 1.7 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated MR_MLE PF01188.16 ETO15594.1 - 1e-12 48.3 0.0 1.6e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_C PF13378.1 ETO15594.1 - 5e-08 32.9 0.0 2.3e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 Enolase C-terminal domain-like AAA PF00004.24 ETO15595.1 - 1.2e-37 129.0 0.0 3.3e-37 127.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 ETO15595.1 - 7.9e-07 28.8 0.0 3.1e-06 26.9 0.0 2.1 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.7 ETO15595.1 - 1.6e-05 24.1 0.0 3.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 ETO15595.1 - 2.7e-05 24.3 0.3 0.0027 17.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 ETO15595.1 - 0.00021 21.0 0.0 0.0011 18.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 ETO15595.1 - 0.003 16.3 0.2 0.0075 15.0 0.0 1.7 2 0 0 2 2 2 1 TIP49 C-terminus MIT PF04212.13 ETO15595.1 - 0.0098 15.7 1.2 0.034 14.0 0.9 1.9 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_16 PF13191.1 ETO15595.1 - 0.012 15.6 0.6 0.044 13.7 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 ETO15595.1 - 0.016 14.9 0.0 0.048 13.4 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 ETO15595.1 - 0.024 15.4 0.0 0.12 13.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 ETO15595.1 - 0.028 13.5 0.2 0.091 11.9 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 ETO15595.1 - 0.045 13.1 0.0 0.34 10.2 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_14 PF13173.1 ETO15595.1 - 0.052 13.4 0.0 0.16 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain PH PF00169.24 ETO15596.1 - 4.3e-10 39.7 0.7 4.3e-10 39.7 0.5 3.0 3 2 0 3 3 3 1 PH domain PH_11 PF15413.1 ETO15596.1 - 0.022 15.0 0.6 0.022 15.0 0.4 2.8 2 2 0 2 2 2 0 Pleckstrin homology domain CinA PF02464.12 ETO15596.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Competence-damaged protein Glu_cyclase_2 PF05096.7 ETO15597.1 - 1.3e-33 116.1 0.4 5.1e-33 114.2 0.3 1.7 1 1 0 1 1 1 1 Glutamine cyclotransferase OLF PF02191.11 ETO15597.1 - 0.0046 16.2 0.0 0.011 15.0 0.0 1.6 1 0 0 1 1 1 1 Olfactomedin-like domain SNARE_assoc PF09335.6 ETO15598.1 - 1.8e-10 41.0 2.2 1.8e-10 41.0 1.5 3.6 3 1 1 4 4 4 1 SNARE associated Golgi protein Peptidase_M56 PF05569.6 ETO15598.1 - 0.022 13.7 1.6 0.045 12.7 0.0 2.2 3 0 0 3 3 3 0 BlaR1 peptidase M56 DUF1049 PF06305.6 ETO15598.1 - 0.027 13.9 0.0 0.027 13.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) FtsL PF04999.8 ETO15598.1 - 0.048 13.3 0.9 0.41 10.3 0.1 2.6 2 0 0 2 2 2 0 Cell division protein FtsL DUF3357 PF11837.3 ETO15598.1 - 0.085 12.7 0.1 3.9 7.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) DUF4234 PF14018.1 ETO15598.1 - 0.089 12.5 4.4 0.45 10.3 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4234) ASFV_J13L PF05568.6 ETO15598.1 - 0.096 12.2 0.1 0.23 10.9 0.1 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein Orbi_NS3 PF01616.11 ETO15598.1 - 0.5 9.3 6.8 0.97 8.3 0.7 2.9 3 0 0 3 3 3 0 Orbivirus NS3 GP41 PF00517.12 ETO15598.1 - 1 8.8 8.7 0.34 10.4 0.1 3.1 2 1 1 3 3 3 0 Retroviral envelope protein TPR_12 PF13424.1 ETO15599.1 - 1.7e-81 268.1 13.6 1.7e-23 82.3 1.5 5.6 3 2 1 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETO15599.1 - 1.1e-57 190.4 0.0 1.5e-10 40.6 0.0 8.5 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_1 PF00515.23 ETO15599.1 - 3.7e-49 162.4 50.0 9.4e-09 34.5 1.3 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_11 PF13414.1 ETO15599.1 - 5.6e-49 163.6 45.1 5.4e-13 48.3 2.4 6.5 3 2 3 6 6 6 6 TPR repeat TPR_7 PF13176.1 ETO15599.1 - 2.1e-44 145.8 9.3 2.3e-05 23.8 0.0 8.6 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_2 PF07719.12 ETO15599.1 - 5.3e-39 128.9 34.3 6.4e-07 28.8 0.6 9.2 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_8 PF13181.1 ETO15599.1 - 2.3e-38 127.0 56.3 8e-09 34.6 2.1 9.8 10 0 0 10 10 9 8 Tetratricopeptide repeat TPR_17 PF13431.1 ETO15599.1 - 5.4e-20 69.8 12.3 0.0021 18.1 0.3 8.7 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 ETO15599.1 - 2.6e-14 52.4 0.0 2.1 9.1 0.0 7.7 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO15599.1 - 2.5e-13 49.5 12.6 0.11 12.9 0.1 7.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO15599.1 - 4.2e-13 49.5 1.7 7.4e-05 23.3 0.0 5.5 3 2 4 7 7 6 4 Tetratricopeptide repeat DUF2225 PF09986.4 ETO15599.1 - 5.9e-09 35.7 18.4 3e-06 26.8 0.5 4.5 1 1 1 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) Apc3 PF12895.2 ETO15599.1 - 4.4e-07 29.9 24.6 0.022 14.9 2.2 4.7 1 1 3 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 ETO15599.1 - 5.4e-07 28.7 0.8 1.5 8.1 0.0 6.6 7 0 0 7 7 7 1 SHNi-TPR TPR_19 PF14559.1 ETO15599.1 - 0.00013 22.2 3.6 0.54 10.6 0.5 4.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_3 PF07720.7 ETO15599.1 - 0.00048 19.8 25.0 0.0061 16.3 0.4 4.9 6 0 0 6 6 4 3 Tetratricopeptide repeat MIT PF04212.13 ETO15599.1 - 0.00049 19.9 19.8 19 5.2 0.0 7.4 7 0 0 7 7 7 0 MIT (microtubule interacting and transport) domain DUF627 PF04781.7 ETO15599.1 - 0.0011 18.5 10.4 1 8.9 0.0 5.7 3 3 1 5 5 5 1 Protein of unknown function (DUF627) PPR PF01535.15 ETO15599.1 - 0.037 13.9 13.8 1.2 9.2 0.1 6.7 8 0 0 8 8 7 0 PPR repeat TPR_9 PF13371.1 ETO15599.1 - 0.037 13.8 0.0 0.34 10.7 0.0 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat ATP-synt_F PF01990.12 ETO15599.1 - 0.044 14.1 0.3 1 9.8 0.0 2.9 3 0 0 3 3 2 0 ATP synthase (F/14-kDa) subunit SPO22 PF08631.5 ETO15599.1 - 0.48 9.4 10.8 2.7 7.0 0.1 4.3 5 0 0 5 5 5 0 Meiosis protein SPO22/ZIP4 like Foie-gras_1 PF11817.3 ETO15599.1 - 1.3 8.4 7.2 20 4.5 0.1 4.2 4 1 1 5 5 5 0 Foie gras liver health family 1 OEP PF02321.13 ETO15599.1 - 1.6 8.2 9.8 18 4.8 1.9 3.8 3 1 0 3 3 3 0 Outer membrane efflux protein CSD PF00313.17 ETO15601.1 - 0.021 14.5 0.0 0.33 10.7 0.0 2.8 3 1 0 3 3 3 0 'Cold-shock' DNA-binding domain SoxE PF06525.6 ETO15601.1 - 0.36 10.0 7.8 0.85 8.8 5.4 1.5 1 0 0 1 1 1 0 Sulfocyanin (SoxE) Mucin PF01456.12 ETO15601.1 - 0.61 9.8 19.9 1.4 8.7 13.8 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.7 ETO15601.1 - 0.8 7.3 5.6 1.1 6.9 3.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 ETO15601.1 - 1.2 8.8 18.0 0.27 10.9 10.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) WD40 PF00400.27 ETO15603.1 - 2.3e-51 169.9 3.8 3.9e-11 42.3 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO15603.1 - 3.3e-12 45.3 0.3 0.0012 17.0 0.0 4.0 1 1 2 4 4 4 4 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO15603.1 - 2.6e-07 30.5 0.2 0.011 15.4 0.0 3.0 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 ETO15603.1 - 7.9e-05 22.2 0.1 0.016 14.7 0.0 2.9 1 1 0 1 1 1 1 PQQ-like domain DUF1797 PF08796.5 ETO15603.1 - 0.00052 19.8 0.0 1 9.2 0.0 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF1797) Cytochrom_D1 PF02239.11 ETO15603.1 - 0.00094 17.5 0.0 0.011 14.0 0.0 2.4 1 1 1 3 3 3 1 Cytochrome D1 heme domain Hira PF07569.6 ETO15603.1 - 0.023 13.9 0.5 0.37 9.9 0.0 2.9 2 2 3 5 5 5 0 TUP1-like enhancer of split Nbas_N PF15492.1 ETO15603.1 - 0.026 13.6 0.5 0.85 8.6 0.0 2.9 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 ETO15603.1 - 0.12 12.0 4.5 27 4.5 0.0 4.7 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat HSP70 PF00012.15 ETO15604.1 - 8.5e-24 83.4 0.0 1.1e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein S-AdoMet_synt_C PF02773.11 ETO15605.1 - 3.2e-62 208.3 0.3 6.4e-62 207.3 0.2 1.5 1 1 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 ETO15605.1 - 2.4e-20 72.6 0.3 4e-20 71.9 0.2 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain RPA_C PF08784.6 ETO15605.1 - 0.054 13.9 0.1 2.1 8.8 0.1 2.3 2 0 0 2 2 2 0 Replication protein A C terminal Glyco_tranf_2_2 PF10111.4 ETO15605.1 - 0.076 12.0 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 S-antigen PF05756.6 ETO15605.1 - 4.1 7.4 4.8 6.6 6.7 0.9 2.3 2 0 0 2 2 2 0 S-antigen protein S-AdoMet_synt_N PF00438.15 ETO15606.1 - 7.1e-38 128.8 0.3 9.3e-38 128.4 0.2 1.1 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain DUF2312 PF10073.4 ETO15606.1 - 0.035 13.4 0.4 0.049 12.9 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) SNARE PF05739.14 ETO15607.1 - 8.3e-11 41.4 4.7 3.2e-05 23.5 0.1 3.3 3 0 0 3 3 3 2 SNARE domain Fib_alpha PF08702.5 ETO15607.1 - 0.0038 17.3 3.3 0.0038 17.3 2.3 2.7 3 0 0 3 3 3 1 Fibrinogen alpha/beta chain family Herpes_US9 PF06072.6 ETO15607.1 - 0.04 13.7 0.2 0.13 12.1 0.1 1.9 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 SprA-related PF12118.3 ETO15607.1 - 0.33 10.2 19.3 0.46 9.7 13.4 1.2 1 0 0 1 1 1 0 SprA-related family CobN-Mg_chel PF02514.11 ETO15607.1 - 0.94 6.7 9.0 1.1 6.5 6.2 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase YscO PF07321.7 ETO15607.1 - 0.98 9.2 21.4 10 5.9 0.0 3.2 3 0 0 3 3 3 0 Type III secretion protein YscO Serinc PF03348.10 ETO15607.1 - 1.5 7.4 6.9 3 6.4 4.7 1.8 1 1 0 1 1 1 0 Serine incorporator (Serinc) CDC37_N PF03234.9 ETO15607.1 - 1.9 8.7 19.9 0.2 11.9 2.4 2.3 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding DUF1764 PF08576.5 ETO15607.1 - 7.1 7.4 17.8 1.2 9.9 4.6 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) AAA_5 PF07728.9 ETO15609.1 - 8.2e-20 70.9 0.0 1.2e-11 44.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 ETO15609.1 - 0.00023 21.0 0.0 0.019 14.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 ETO15609.1 - 0.00062 19.6 0.0 0.0049 16.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 ETO15609.1 - 0.0038 16.9 0.1 0.064 12.9 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase AAA PF00004.24 ETO15609.1 - 0.0052 16.9 0.0 0.016 15.4 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETO15609.1 - 0.0091 16.0 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Miro PF08477.8 ETO15609.1 - 0.017 15.6 0.0 0.045 14.2 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Zeta_toxin PF06414.7 ETO15609.1 - 0.031 13.3 0.0 0.067 12.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 ETO15609.1 - 0.036 14.8 0.0 0.15 12.8 0.0 2.1 2 1 1 3 3 3 0 AAA domain AAA_28 PF13521.1 ETO15609.1 - 0.036 14.0 0.0 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 ETO15609.1 - 0.038 12.8 0.0 0.052 12.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activ_2 PF14532.1 ETO15609.1 - 0.047 13.7 0.0 0.3 11.1 0.0 2.4 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_3 PF07726.6 ETO15609.1 - 0.057 13.0 0.0 0.22 11.1 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 ETO15609.1 - 0.074 11.9 0.0 0.16 10.7 0.0 1.7 1 1 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_22 PF13401.1 ETO15609.1 - 0.11 12.5 0.0 0.86 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain NBP1 PF08537.5 ETO15609.1 - 0.12 11.5 1.4 2.5 7.2 0.1 2.1 2 0 0 2 2 2 0 Fungal Nap binding protein NBP1 WD40 PF00400.27 ETO15610.1 - 6.1e-05 22.7 0.1 0.0003 20.5 0.2 1.9 2 0 0 2 2 2 1 WD domain, G-beta repeat UpxZ PF06603.6 ETO15610.1 - 0.04 13.9 0.0 0.048 13.6 0.0 1.3 1 1 0 1 1 1 0 UpxZ family of transcription anti-terminator antagonists Nup160 PF11715.3 ETO15610.1 - 0.07 11.2 0.0 0.07 11.2 0.0 1.0 1 0 0 1 1 1 0 Nucleoporin Nup120/160 zf-C3HC4_2 PF13923.1 ETO15611.1 - 0.017 15.1 3.8 0.16 11.9 2.6 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.15 ETO15611.1 - 1.6 8.2 7.2 0.2 11.1 1.5 2.2 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger WD40 PF00400.27 ETO15612.1 - 5.7e-112 362.0 39.7 8.5e-13 47.6 0.1 11.5 11 0 0 11 11 11 11 WD domain, G-beta repeat Nup160 PF11715.3 ETO15612.1 - 3.4e-17 61.8 20.2 0.0098 14.0 0.1 9.4 4 3 5 10 10 10 7 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO15612.1 - 1e-05 24.0 0.4 5.7e-05 21.5 0.0 2.2 2 0 0 2 2 2 1 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO15612.1 - 0.0003 20.3 3.4 0.062 12.7 0.0 4.3 4 1 2 6 6 6 1 PQQ-like domain PD40 PF07676.7 ETO15612.1 - 0.0061 16.2 2.7 7.4 6.3 0.1 4.4 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO15612.1 - 0.015 15.5 0.1 13 6.0 0.0 3.8 2 1 1 3 3 3 0 Resistin RicinB_lectin_2 PF14200.1 ETO15612.1 - 0.23 11.8 8.0 22 5.4 0.1 5.6 4 3 1 6 6 6 0 Ricin-type beta-trefoil lectin domain-like Actin PF00022.14 ETO15613.1 - 7.9e-106 353.7 0.1 2.4e-57 194.1 0.0 2.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.8 ETO15613.1 - 8.8e-06 24.5 0.0 0.0045 15.6 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein Kelch_6 PF13964.1 ETO15614.1 - 0.048 13.8 0.0 2.2 8.5 0.0 3.1 3 0 0 3 3 3 0 Kelch motif Kelch_1 PF01344.20 ETO15614.1 - 0.18 11.3 1.3 8.5 6.0 0.0 2.8 3 0 0 3 3 3 0 Kelch motif tRNA_edit PF04073.10 ETO15615.1 - 7.7e-09 35.4 0.0 9.7e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain Cupin_8 PF13621.1 ETO15616.1 - 8e-40 136.9 1.1 9.2e-40 136.7 0.8 1.0 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 ETO15616.1 - 1.4e-05 25.2 0.8 5.2e-05 23.4 0.6 2.0 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 ETO15616.1 - 8.3e-05 21.9 0.2 0.00027 20.2 0.2 1.8 1 1 0 1 1 1 1 Cupin superfamily protein ARD PF03079.9 ETO15616.1 - 0.01 15.7 0.0 0.023 14.6 0.0 1.6 1 1 0 1 1 1 0 ARD/ARD' family Cupin_8 PF13621.1 ETO15617.1 - 5.6e-15 55.5 0.1 7.6e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain N-glycanase_N PF09112.5 ETO15617.1 - 0.0081 15.5 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Peptide-N-glycosidase F, N terminal DnaJ PF00226.26 ETO15618.1 - 2.9e-13 49.3 0.5 9.9e-13 47.6 0.4 1.9 1 1 0 1 1 1 1 DnaJ domain DUF469 PF04320.9 ETO15618.1 - 0.03 15.1 0.0 0.043 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein with unknown function (DUF469) DUF643 PF04867.7 ETO15618.1 - 0.059 13.7 0.4 0.099 13.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF643) DUF3395 PF11875.3 ETO15619.1 - 2.5e-17 62.8 4.0 2e-16 59.9 2.7 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3395) CCSMST1 PF15013.1 ETO15619.1 - 0.081 12.8 0.3 0.44 10.4 0.0 2.4 2 1 0 2 2 2 0 CCSMST1 family EMP70 PF02990.11 ETO15621.1 - 8.5e-119 397.3 22.8 9.9e-119 397.1 15.8 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 DUF2636 PF11120.3 ETO15621.1 - 3.1 7.3 8.1 7.3 6.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2636) WD40 PF00400.27 ETO15622.1 - 5.3e-37 124.3 8.2 8e-12 44.5 0.1 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO15622.1 - 0.00078 17.6 0.3 0.075 11.1 0.0 2.8 2 1 1 3 3 3 2 Nucleoporin Nup120/160 VGLL4 PF15245.1 ETO15623.1 - 0.0095 15.7 2.6 0.0095 15.7 1.8 1.4 2 0 0 2 2 2 1 Transcription cofactor vestigial-like protein 4 Kelch_6 PF13964.1 ETO15624.1 - 4.2e-09 36.2 7.6 1.6e-05 24.8 0.4 4.1 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO15624.1 - 2.3e-08 33.4 8.8 2.1e-05 23.9 0.7 4.4 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO15624.1 - 5.9e-05 22.7 1.1 0.0035 17.0 0.2 2.9 1 1 1 2 2 2 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO15624.1 - 8.9e-05 22.5 0.1 0.0031 17.6 0.0 3.2 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO15624.1 - 9.3e-05 22.0 4.1 0.0064 16.2 0.3 3.5 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO15624.1 - 0.0027 17.6 0.6 15 5.6 0.2 4.1 4 0 0 4 4 4 2 Kelch motif DUF228 PF02989.9 ETO15624.1 - 0.058 12.9 2.6 0.3 10.6 1.0 2.4 1 1 1 2 2 2 0 Lyme disease proteins of unknown function LRR_6 PF13516.1 ETO15625.1 - 0.0092 15.9 5.2 8 6.8 0.0 4.4 4 0 0 4 4 4 2 Leucine Rich repeat Kinesin PF00225.18 ETO15626.1 - 6e-22 77.7 0.1 7.3e-22 77.5 0.1 1.1 1 0 0 1 1 1 1 Kinesin motor domain Pribosyl_synth PF14572.1 ETO15627.1 - 1.1e-25 90.4 1.0 2.1e-25 89.5 0.2 1.8 2 1 1 3 3 3 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 ETO15627.1 - 3.5e-19 68.6 1.4 1.4e-18 66.7 0.3 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 ETO15627.1 - 6e-09 35.6 0.1 1.2e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 ETO15627.1 - 0.011 14.9 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Atg14 PF10186.4 ETO15628.1 - 0.0016 17.4 16.7 0.0098 14.8 11.0 1.9 1 1 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 CENP-Q PF13094.1 ETO15628.1 - 0.025 14.6 3.9 0.035 14.1 2.3 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Resolvase PF00239.16 ETO15628.1 - 0.037 13.9 0.5 0.037 13.9 0.4 1.9 2 0 0 2 2 2 0 Resolvase, N terminal domain DUF1885 PF08968.5 ETO15628.1 - 0.1 12.2 0.2 0.34 10.6 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1885) DUF3458 PF11940.3 ETO15628.1 - 0.13 11.0 0.9 0.15 10.8 0.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3458) DUF1090 PF06476.7 ETO15628.1 - 0.39 10.3 9.4 0.12 12.0 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) Baculo_p24 PF05073.7 ETO15628.1 - 0.94 9.0 5.0 0.42 10.1 0.2 2.0 1 1 1 2 2 2 0 Baculovirus P24 capsid protein Osmo_CC PF08946.5 ETO15628.1 - 1.1 9.3 5.7 2.5 8.1 0.4 2.8 3 0 0 3 3 3 0 Osmosensory transporter coiled coil D5_N PF08706.6 ETO15628.1 - 1.4 8.9 5.4 0.58 10.2 1.7 1.7 2 0 0 2 2 2 0 D5 N terminal like IncA PF04156.9 ETO15628.1 - 2.1 7.9 7.7 3.2 7.3 5.3 1.3 1 1 0 1 1 1 0 IncA protein TMPIT PF07851.8 ETO15628.1 - 3.2 6.7 8.2 9.1 5.2 1.8 2.0 1 1 0 2 2 2 0 TMPIT-like protein DUF342 PF03961.8 ETO15628.1 - 5.5 5.2 9.5 6.6 5.0 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Kelch_4 PF13418.1 ETO15630.1 - 4.4e-07 29.5 0.2 4.3e-05 23.1 0.0 2.5 1 1 1 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO15630.1 - 4.1e-05 23.0 9.3 0.0003 20.2 0.4 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO15630.1 - 4.7e-05 23.3 4.2 0.16 12.1 0.2 3.0 2 1 1 3 3 3 2 Kelch motif Kelch_5 PF13854.1 ETO15630.1 - 0.00068 19.5 0.9 0.07 13.1 1.1 2.4 2 0 0 2 2 2 1 Kelch motif Mito_fiss_reg PF05308.6 ETO15630.1 - 0.019 14.3 0.0 0.027 13.8 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Kelch_3 PF13415.1 ETO15630.1 - 0.019 15.0 0.0 0.22 11.7 0.0 2.2 2 0 0 2 2 2 0 Galactose oxidase, central domain YicC_N PF03755.8 ETO15631.1 - 0.11 12.4 0.5 0.12 12.2 0.4 1.2 1 0 0 1 1 1 0 YicC-like family, N-terminal region Kelch_1 PF01344.20 ETO15633.1 - 1.6e-05 24.3 4.3 0.00065 19.1 0.2 4.0 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 ETO15633.1 - 0.00012 21.7 3.5 0.0018 17.9 0.1 3.7 5 0 0 5 5 5 1 Kelch motif Kelch_6 PF13964.1 ETO15633.1 - 0.00013 21.9 9.3 0.27 11.4 0.4 4.5 3 1 1 4 4 4 3 Kelch motif Kelch_4 PF13418.1 ETO15633.1 - 0.00015 21.4 0.3 0.35 10.6 0.1 3.2 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO15633.1 - 1 9.3 5.5 14 5.7 0.2 4.3 5 0 0 5 5 5 0 Kelch motif WD40 PF00400.27 ETO15634.1 - 2.3e-150 483.7 40.4 1.1e-10 40.9 0.9 16.1 15 1 1 16 16 16 16 WD domain, G-beta repeat Nup160 PF11715.3 ETO15634.1 - 4.9e-17 61.2 20.5 0.32 9.0 0.3 12.3 1 1 9 10 10 10 9 Nucleoporin Nup120/160 DUF1258 PF06869.7 ETO15634.1 - 4e-05 22.8 2.4 4.1 6.4 0.0 5.6 4 3 2 7 7 7 2 Protein of unknown function (DUF1258) Pentapeptide_4 PF13599.1 ETO15634.1 - 9.3e-05 22.1 3.2 0.00031 20.4 2.2 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) DUF3732 PF12532.3 ETO15634.1 - 0.00012 21.7 3.3 8.9 5.7 0.0 6.3 6 2 1 7 7 7 1 Protein of unknown function (DUF3732) SGL PF08450.7 ETO15634.1 - 0.00013 21.3 1.9 2.8 7.2 0.0 5.5 2 2 3 6 6 6 1 SMP-30/Gluconolaconase/LRE-like region DUF1938 PF09153.5 ETO15634.1 - 0.00099 18.8 7.4 1.7 8.5 0.1 5.9 5 2 2 7 7 7 1 Domain of unknown function (DUF1938) TolB_N PF04052.8 ETO15634.1 - 0.0014 18.6 0.0 36 4.4 0.0 6.2 9 0 0 9 9 9 0 TolB amino-terminal domain Pentapeptide PF00805.17 ETO15634.1 - 0.0017 17.5 0.4 0.0032 16.6 0.3 1.4 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 ETO15634.1 - 0.026 14.3 0.3 0.026 14.3 0.2 3.0 3 0 0 3 3 2 0 Pentapeptide repeats (9 copies) NYD-SP28_assoc PF14775.1 ETO15634.1 - 0.05 13.3 6.9 20 4.9 0.0 7.0 10 0 0 10 10 9 0 Sperm tail C-terminal domain Microvir_J PF04726.8 ETO15634.1 - 0.15 12.0 0.0 2.8 7.9 0.0 3.1 2 0 0 2 2 2 0 Microvirus J protein PD40 PF07676.7 ETO15634.1 - 0.27 10.9 23.6 3.8 7.2 0.0 7.9 10 0 0 10 10 10 0 WD40-like Beta Propeller Repeat IncA PF04156.9 ETO15635.1 - 0.0069 16.0 7.6 0.011 15.3 5.3 1.4 1 0 0 1 1 1 1 IncA protein Wzy_C PF04932.10 ETO15635.1 - 0.0076 16.0 5.1 0.0097 15.7 3.5 1.2 1 0 0 1 1 1 1 O-Antigen ligase 2TM PF13239.1 ETO15635.1 - 0.51 10.4 8.3 1.1 9.3 5.8 1.5 1 0 0 1 1 1 0 2TM domain DUF2207 PF09972.4 ETO15635.1 - 0.59 8.6 8.6 0.64 8.5 6.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3304 PF11745.3 ETO15635.1 - 1.4 9.1 4.5 0.29 11.3 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3304) Halogen_Hydrol PF10112.4 ETO15635.1 - 1.4 8.2 5.8 2.1 7.6 4.0 1.3 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF3043 PF11241.3 ETO15635.1 - 7.4 6.1 6.8 10 5.6 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Fumble PF03630.9 ETO15636.1 - 3.3e-43 147.8 0.0 4.1e-43 147.5 0.0 1.0 1 0 0 1 1 1 1 Fumble SR-25 PF10500.4 ETO15638.1 - 0.22 10.9 12.4 0.064 12.7 6.3 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 ETO15638.1 - 2.3 8.2 12.7 0.37 10.8 5.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF755) RRM_1 PF00076.17 ETO15639.1 - 1.4e-35 120.7 0.1 6.2e-15 54.5 0.1 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO15639.1 - 4.5e-23 81.0 0.1 1.3e-08 34.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO15639.1 - 3.3e-14 52.4 0.7 0.0038 17.0 0.1 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phycobilisome PF00502.14 ETO15639.1 - 0.096 12.4 0.2 0.23 11.1 0.0 1.7 2 0 0 2 2 2 0 Phycobilisome protein CDC45 PF02724.9 ETO15640.1 - 0.0023 16.0 6.1 0.0023 16.0 4.2 1.1 1 0 0 1 1 1 1 CDC45-like protein Mnd1 PF03962.10 ETO15640.1 - 0.14 11.8 16.2 0.2 11.2 11.2 1.3 1 0 0 1 1 1 0 Mnd1 family DDHD PF02862.12 ETO15640.1 - 0.19 11.5 5.6 0.24 11.1 3.9 1.3 1 0 0 1 1 1 0 DDHD domain eIF-3c_N PF05470.7 ETO15640.1 - 1.9 6.4 15.2 2.4 6.1 10.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus MRP-S27 PF10037.4 ETO15640.1 - 4.1 6.2 11.3 5.4 5.8 7.8 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Acylphosphatase PF00708.13 ETO15641.1 - 6.2e-13 48.6 1.6 1e-12 47.9 0.4 1.8 1 1 1 2 2 2 1 Acylphosphatase DUF739 PF05339.6 ETO15641.1 - 0.00066 19.4 0.5 0.37 10.5 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF739) CmcH_NodU PF02543.10 ETO15641.1 - 0.011 14.9 0.3 0.012 14.7 0.2 1.0 1 0 0 1 1 1 0 Carbamoyltransferase EBV-NA3 PF05009.7 ETO15641.1 - 0.07 12.3 0.1 0.089 12.0 0.1 1.3 1 1 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) tRNA_anti-codon PF01336.20 ETO15641.1 - 0.083 12.7 1.0 0.13 12.0 0.2 1.8 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain Ipi1_N PF12333.3 ETO15641.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation WD40 PF00400.27 ETO15642.1 - 1.7e-80 262.2 19.4 3.3e-13 48.9 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat PQQ_2 PF13360.1 ETO15642.1 - 7.2e-10 38.7 3.2 5.4e-05 22.7 0.1 3.5 1 1 2 3 3 3 3 PQQ-like domain NACHT PF05729.7 ETO15642.1 - 7.9e-06 25.6 0.0 1.6e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Pentapeptide PF00805.17 ETO15642.1 - 6.8e-05 22.0 0.3 0.00031 19.8 0.2 2.1 1 1 1 2 2 2 1 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 ETO15642.1 - 0.00012 21.8 1.4 0.00017 21.4 0.1 2.0 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) Gmad1 PF10647.4 ETO15642.1 - 0.00021 20.7 2.3 0.0067 15.8 0.2 2.7 2 1 1 3 3 3 2 Lipoprotein LpqB beta-propeller domain Pentapeptide_4 PF13599.1 ETO15642.1 - 0.00039 20.1 0.1 0.0014 18.3 0.1 2.0 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) RelA_SpoT PF04607.12 ETO15642.1 - 0.00042 20.3 0.3 0.0025 17.7 0.2 2.4 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins AAA_22 PF13401.1 ETO15642.1 - 0.016 15.3 0.0 0.049 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain PD40 PF07676.7 ETO15642.1 - 0.18 11.5 5.7 60 3.4 0.0 4.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 ETO15643.1 - 2.5e-21 74.6 11.6 8e-11 41.3 0.6 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO15643.1 - 4.5e-06 25.0 2.0 0.00056 18.1 0.3 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO15643.1 - 0.026 13.2 0.6 0.72 8.5 0.0 2.0 1 1 1 2 2 2 0 Nup133 N terminal like DUF4221 PF13970.1 ETO15643.1 - 0.057 12.7 4.7 0.36 10.1 3.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4221) Tim44 PF04280.10 ETO15645.1 - 1.1e-07 31.8 0.0 1.6e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Tim44-like domain Actin PF00022.14 ETO15646.1 - 3.4e-11 42.2 0.0 2e-08 33.0 0.0 2.1 1 1 0 1 1 1 1 Actin Wbp11 PF09429.5 ETO15647.1 - 0.033 14.1 4.0 0.033 14.1 2.8 2.2 2 0 0 2 2 2 0 WW domain binding protein 11 TBCA PF02970.11 ETO15647.1 - 0.27 11.3 11.1 0.046 13.8 4.2 2.1 2 0 0 2 2 2 0 Tubulin binding cofactor A M60-like PF13402.1 ETO15647.1 - 0.36 9.6 4.7 0.15 10.9 0.2 2.3 2 1 0 2 2 2 0 Peptidase M60-like family ALIX_LYPXL_bnd PF13949.1 ETO15647.1 - 0.53 9.1 9.6 0.16 10.8 4.1 1.8 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV DUF1768 PF08719.6 ETO15647.1 - 0.71 9.5 4.2 0.79 9.4 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1768) DivIC PF04977.10 ETO15648.1 - 0.39 10.2 2.3 1.5 8.3 1.6 2.0 1 0 0 1 1 1 0 Septum formation initiator WD40 PF00400.27 ETO15649.1 - 5.2e-73 238.5 29.3 5e-13 48.3 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat PD40 PF07676.7 ETO15649.1 - 0.0004 19.9 0.7 0.55 9.9 0.0 3.5 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat DRP PF06044.7 ETO15650.1 - 0.0031 16.5 0.5 0.0047 15.9 0.4 1.3 1 0 0 1 1 1 1 Dam-replacing family WD40 PF00400.27 ETO15651.1 - 3.7e-56 185.1 18.9 4.7e-11 42.1 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO15651.1 - 9.3e-13 47.1 1.1 0.0097 14.0 0.0 4.4 2 1 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO15651.1 - 9.2e-05 21.3 4.1 0.0039 16.0 0.7 3.2 2 1 1 3 3 3 2 Nup133 N terminal like PUF PF00806.14 ETO15652.1 - 1.5e-65 213.1 6.9 9.4e-09 34.2 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat SapB_2 PF03489.12 ETO15652.1 - 0.01 15.8 1.7 3.4 7.8 0.0 3.4 3 0 0 3 3 3 0 Saposin-like type B, region 2 SR-25 PF10500.4 ETO15652.1 - 1.2 8.5 17.8 0.025 14.0 7.5 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.4 ETO15652.1 - 4.4 5.4 16.1 6.7 4.8 11.2 1.2 1 0 0 1 1 1 0 Transmembrane protein WD40 PF00400.27 ETO15653.1 - 2.4e-117 379.1 20.2 3.5e-11 42.5 0.0 16.4 16 0 0 16 16 16 14 WD domain, G-beta repeat NACHT PF05729.7 ETO15653.1 - 1.9e-08 34.1 0.0 4.1e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Pentapeptide PF00805.17 ETO15653.1 - 7.1e-07 28.3 1.6 1.6e-06 27.2 1.1 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO15653.1 - 7.4e-06 25.6 0.5 2.2e-05 24.1 0.4 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) PQQ_2 PF13360.1 ETO15653.1 - 8.8e-06 25.3 0.0 0.031 13.7 0.0 3.9 2 1 1 3 3 3 2 PQQ-like domain Nbas_N PF15492.1 ETO15653.1 - 1.6e-05 24.1 2.4 2.7 7.0 0.1 6.0 4 3 1 5 5 5 2 Neuroblastoma-amplified sequence, N terminal AAA_22 PF13401.1 ETO15653.1 - 0.00018 21.6 0.0 0.00069 19.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETO15653.1 - 0.00052 20.3 0.0 0.00052 20.3 0.0 3.5 2 1 1 3 3 2 1 AAA domain PD40 PF07676.7 ETO15653.1 - 0.0017 17.9 2.4 13 5.5 0.1 5.5 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Pentapeptide_3 PF13576.1 ETO15653.1 - 0.0036 17.1 2.2 0.0036 17.1 1.5 3.2 3 1 0 3 3 3 1 Pentapeptide repeats (9 copies) UPF0079 PF02367.12 ETO15653.1 - 0.013 15.1 0.0 0.046 13.3 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 ETO15653.1 - 0.022 15.5 0.0 0.17 12.7 0.0 2.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 ETO15653.1 - 0.15 11.9 0.0 0.4 10.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2265 PF10023.4 ETO15654.1 - 0.021 13.9 2.3 0.046 12.8 1.6 1.6 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) YqzE PF14038.1 ETO15658.1 - 0.057 13.1 0.2 0.1 12.3 0.1 1.4 1 0 0 1 1 1 0 YqzE-like protein Prismane PF03063.15 ETO15660.1 - 0.095 11.0 0.1 0.099 10.9 0.1 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family DUF3450 PF11932.3 ETO15660.1 - 0.19 10.9 12.7 0.32 10.2 8.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) NPV_P10 PF05531.7 ETO15660.1 - 0.22 11.7 5.4 0.064 13.5 1.4 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2400 PF09674.5 ETO15660.1 - 0.36 10.5 10.6 0.065 12.9 4.4 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2400) Reo_sigmaC PF04582.7 ETO15660.1 - 0.45 9.6 3.3 0.2 10.7 0.6 1.6 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF2058 PF09831.4 ETO15660.1 - 0.89 9.4 17.3 0.07 13.0 8.8 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) Atg14 PF10186.4 ETO15660.1 - 1.5 7.6 16.2 0.17 10.7 7.9 1.7 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 BPL_N PF09825.4 ETO15660.1 - 1.8 7.2 5.3 2.2 6.9 3.7 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal SSXT PF05030.7 ETO15660.1 - 2.2 7.9 9.8 4.3 6.9 1.9 2.9 2 2 0 2 2 2 0 SSXT protein (N-terminal region) Occludin_ELL PF07303.8 ETO15660.1 - 4 8.2 13.0 26 5.5 6.6 2.7 2 1 0 2 2 2 0 Occludin homology domain IncA PF04156.9 ETO15660.1 - 5.9 6.4 24.0 7 6.2 11.8 2.2 2 0 0 2 2 2 0 IncA protein NDT80_PhoG PF05224.7 ETO15660.1 - 7.1 6.5 15.7 0.61 10.0 1.4 2.5 1 1 1 2 2 2 0 NDT80 / PhoG like DNA-binding family NTR2 PF15458.1 ETO15660.1 - 7.5 5.7 22.0 0.94 8.6 10.3 2.1 2 0 0 2 2 2 0 Nineteen complex-related protein 2 Leuk-A4-hydro_C PF09127.6 ETO15661.1 - 1.3e-16 60.4 8.0 2.5e-13 49.8 0.2 2.6 3 0 0 3 3 3 2 Leukotriene A4 hydrolase, C-terminal Peptidase_M1 PF01433.15 ETO15661.1 - 1.3e-05 24.4 0.2 2.1e-05 23.8 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 ETO15661.1 - 0.0063 16.5 0.3 0.51 10.3 0.1 2.4 2 0 0 2 2 2 1 Peptidase MA superfamily Coatamer_beta_C PF07718.7 ETO15661.1 - 0.086 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Coatomer beta C-terminal region zf-C2H2_jaz PF12171.3 ETO15662.1 - 0.00086 19.3 8.8 0.0033 17.5 0.6 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 ETO15662.1 - 0.0029 17.7 6.8 0.15 12.3 0.5 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type DUF843 PF05814.6 ETO15662.1 - 0.34 10.7 0.0 0.34 10.7 0.0 3.3 3 0 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) FOP_dimer PF09398.5 ETO15664.1 - 0.0074 16.2 0.3 8.3 6.4 0.0 3.5 4 0 0 4 4 4 2 FOP N terminal dimerisation domain YMF19 PF02326.10 ETO15665.1 - 0.74 10.4 8.2 0.2 12.2 3.0 2.1 2 0 0 2 2 2 0 Plant ATP synthase F0 Arc_trans_TRASH PF08394.5 ETO15667.1 - 0.025 14.7 2.2 0.025 14.7 1.5 2.5 2 1 1 3 3 3 0 Archaeal TRASH domain Brevenin PF03032.10 ETO15668.1 - 0.065 13.0 3.6 2.6 7.9 0.6 2.3 2 0 0 2 2 2 0 Brevenin/esculentin/gaegurin/rugosin family DUF3795 PF12675.2 ETO15668.1 - 0.28 11.3 2.1 0.37 10.9 1.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) DNA_pol3_delta2 PF13177.1 ETO15668.1 - 0.32 10.6 4.0 0.33 10.5 2.7 1.0 1 0 0 1 1 1 0 DNA polymerase III, delta subunit CytadhesinP1 PF12378.3 ETO15668.1 - 2.4 8.1 5.1 0.81 9.6 1.6 1.7 1 1 1 2 2 2 0 Trypsin-sensitive surface-exposed protein DUF3899 PF13038.1 ETO15668.1 - 5.4 7.2 7.6 0.82 9.8 0.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3899) WD40 PF00400.27 ETO15669.1 - 1.1e-14 53.6 3.6 1.4e-10 40.5 0.8 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat zf-TRAF PF02176.13 ETO15669.1 - 4.9e-05 23.6 6.3 4.9e-05 23.6 4.3 2.6 2 1 1 3 3 3 1 TRAF-type zinc finger Nup160 PF11715.3 ETO15669.1 - 0.00021 19.5 0.1 0.0003 19.0 0.1 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 PHP PF02811.14 ETO15669.1 - 0.021 14.6 1.0 0.029 14.1 0.7 1.3 1 0 0 1 1 1 0 PHP domain GvpL_GvpF PF06386.6 ETO15669.1 - 8.3 5.9 10.2 1.4e+02 1.9 7.1 2.2 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF HECT PF00632.20 ETO15671.1 - 1.3e-74 251.1 0.5 6.6e-74 248.9 0.2 1.7 1 1 0 2 2 2 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.13 ETO15672.1 - 1.8e-05 23.7 2.4 3.3e-05 22.8 1.7 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.10 ETO15672.1 - 0.019 14.4 2.1 0.33 10.5 0.1 2.7 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger SPRY PF00622.23 ETO15673.1 - 2.3e-22 79.3 0.5 8e-22 77.6 0.4 2.0 1 0 0 1 1 1 1 SPRY domain Mem_trans PF03547.13 ETO15674.1 - 1.3 7.1 18.5 0.059 11.6 0.1 2.3 2 0 0 2 2 2 0 Membrane transport protein PAT1 PF09770.4 ETO15674.1 - 2.1 6.4 59.5 0.022 13.0 34.6 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Raftlin PF15250.1 ETO15674.1 - 2.5 6.5 29.1 2.5 6.5 12.7 2.1 2 0 0 2 2 2 0 Raftlin Neur_chan_memb PF02932.11 ETO15674.1 - 9.8 5.9 20.8 4 7.2 9.2 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region WD40 PF00400.27 ETO15676.1 - 8.9e-79 256.8 17.7 6.5e-13 48.0 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO15676.1 - 7.9e-10 37.4 8.8 0.0055 14.9 0.0 4.3 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO15676.1 - 6.6e-07 27.9 1.7 0.00082 17.7 0.1 3.4 2 1 3 5 5 5 3 Cytochrome D1 heme domain RicinB_lectin_2 PF14200.1 ETO15676.1 - 0.14 12.5 4.5 4.5 7.7 0.1 3.8 1 1 2 4 4 4 0 Ricin-type beta-trefoil lectin domain-like PD40 PF07676.7 ETO15676.1 - 1.1 9.0 17.3 8.6 6.1 0.0 5.9 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 ETO15677.1 - 1.6e-32 110.1 18.1 2.8e-12 45.9 0.0 4.4 4 1 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO15677.1 - 1.7e-09 36.3 1.8 0.0086 14.2 0.2 3.6 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Kelch_1 PF01344.20 ETO15678.1 - 4.3e-05 22.9 3.5 0.00094 18.6 0.2 3.2 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETO15678.1 - 0.0003 20.4 1.3 0.65 9.8 0.0 3.4 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO15678.1 - 0.0058 16.7 1.8 0.82 9.9 0.3 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO15678.1 - 0.02 14.6 3.7 0.54 10.1 0.6 3.6 3 2 0 3 3 3 0 Kelch motif WD40 PF00400.27 ETO15679.1 - 2.1e-74 242.9 13.4 4.9e-12 45.2 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO15679.1 - 3.7e-07 28.6 3.9 0.45 8.5 0.0 4.7 1 1 4 5 5 5 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO15679.1 - 1.2e-05 23.8 0.2 0.014 13.7 0.0 3.6 1 1 4 5 5 5 3 Cytochrome D1 heme domain Kelch_6 PF13964.1 ETO15679.1 - 8.7e-05 22.5 4.4 0.15 12.2 0.2 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO15679.1 - 0.0001 21.7 0.9 0.82 9.2 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 ETO15679.1 - 0.0045 16.9 0.2 0.74 9.8 0.1 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO15679.1 - 0.074 12.8 0.2 1.3 8.8 0.0 3.2 2 0 0 2 2 2 0 Kelch motif Exo_endo_phos_2 PF14529.1 ETO15681.1 - 8.7e-09 35.0 0.4 2.2e-08 33.6 0.1 1.9 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase DAOA PF15199.1 ETO15681.1 - 0.36 11.4 0.1 0.36 11.4 0.0 2.4 3 0 0 3 3 3 0 D-amino acid oxidase activator Merozoite_SPAM PF07133.6 ETO15683.1 - 0.46 10.3 5.5 0.13 12.1 0.4 2.1 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) DUF2011 PF09428.5 ETO15684.1 - 0.091 12.6 3.5 0.17 11.7 2.4 1.5 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2011) KfrA_N PF11740.3 ETO15685.1 - 0.052 14.0 1.2 13 6.2 0.1 2.6 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term DUF4303 PF14136.1 ETO15685.1 - 0.13 11.9 7.9 4.3 6.9 3.3 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4303) GOLD_2 PF13897.1 ETO15685.1 - 1.1 9.5 5.4 0.61 10.3 0.2 2.4 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking CorA PF01544.13 ETO15685.1 - 2 7.3 6.0 2.2 7.2 0.3 2.6 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein HCaRG PF07258.9 ETO15686.1 - 1.6e-12 47.3 3.6 2.4e-12 46.7 1.8 1.7 2 0 0 2 2 2 1 HCaRG protein PIP5K PF01504.13 ETO15687.1 - 4.8e-68 229.0 0.9 6.1e-68 228.6 0.7 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Rhodanese PF00581.15 ETO15688.1 - 5.3e-11 42.8 0.7 2.6e-09 37.4 0.1 2.2 1 1 0 2 2 2 2 Rhodanese-like domain PNK3P PF08645.6 ETO15688.1 - 0.073 12.5 2.3 0.11 11.9 1.6 1.3 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase bZIP_1 PF00170.16 ETO15691.1 - 0.0025 17.7 2.8 0.0025 17.7 2.0 14.9 17 1 0 17 17 17 3 bZIP transcription factor DivIVA PF05103.8 ETO15691.1 - 0.0081 16.2 16.8 0.0081 16.2 11.6 13.6 7 5 5 13 13 13 3 DivIVA protein Spc7 PF08317.6 ETO15692.1 - 7.4e-07 28.1 27.0 7.4e-07 28.1 18.7 2.3 1 1 1 2 2 1 1 Spc7 kinetochore protein Cast PF10174.4 ETO15692.1 - 0.00025 19.2 39.3 0.00033 18.8 27.3 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Motile_Sperm PF00635.21 ETO15692.1 - 0.00028 20.4 1.5 0.00091 18.8 0.0 2.5 2 0 0 2 2 2 1 MSP (Major sperm protein) domain DUF3479 PF11965.3 ETO15692.1 - 0.026 14.3 0.8 0.026 14.3 0.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3479) Reo_sigmaC PF04582.7 ETO15692.1 - 0.091 11.9 11.6 0.24 10.5 6.3 2.2 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DUF869 PF05911.6 ETO15692.1 - 0.79 7.8 37.4 1 7.4 25.9 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) TMF_TATA_bd PF12325.3 ETO15692.1 - 0.91 9.2 44.6 0.38 10.4 8.8 3.5 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding ATG16 PF08614.6 ETO15692.1 - 3.3 7.5 45.5 6.2 6.5 16.4 2.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF3708 PF12501.3 ETO15692.1 - 4.3 7.1 7.8 0.88 9.3 0.7 2.2 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter MAD PF05557.8 ETO15692.1 - 6.3 4.7 52.6 13 3.7 9.9 2.2 1 1 1 2 2 2 0 Mitotic checkpoint protein DUF940 PF06082.6 ETO15692.1 - 6.6 5.1 16.4 8.3 4.8 11.3 1.2 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) FGGY_C PF02782.11 ETO15693.1 - 1.6e-22 80.1 0.0 2.1e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain STAT6_C PF14596.1 ETO15697.1 - 0.0049 16.8 0.2 0.024 14.5 0.0 2.1 2 0 0 2 2 2 1 STAT6 C-terminal EPL1 PF10513.4 ETO15697.1 - 5.8 7.1 8.0 0.51 10.5 1.0 2.4 3 0 0 3 3 3 0 Enhancer of polycomb-like DUF2457 PF10446.4 ETO15699.1 - 0.00095 18.0 3.9 0.0012 17.6 2.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Secretin_N_2 PF07655.8 ETO15699.1 - 0.0014 18.9 2.3 0.0014 18.9 1.6 1.8 2 0 0 2 2 2 1 Secretin N-terminal domain MAD PF05557.8 ETO15699.1 - 0.0032 15.6 0.2 0.0046 15.1 0.1 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein GPCR_chapero_1 PF11904.3 ETO15699.1 - 0.0075 15.4 0.8 0.0095 15.1 0.5 1.2 1 0 0 1 1 1 1 GPCR-chaperone PBP1_TM PF14812.1 ETO15699.1 - 1.8 8.9 8.1 3.8 7.8 5.6 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Kinesin PF00225.18 ETO15700.1 - 4e-06 25.7 11.0 0.00016 20.4 0.6 2.1 1 1 1 2 2 2 2 Kinesin motor domain Mfa2 PF08842.5 ETO15700.1 - 0.15 11.3 13.9 0.16 11.2 8.6 1.7 1 1 1 2 2 2 0 Fimbrillin-A associated anchor proteins Mfa1 and Mfa2 cNMP_binding PF00027.24 ETO15701.1 - 1.2e-06 28.2 0.1 0.00073 19.3 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pox_E10 PF04805.7 ETO15701.1 - 0.15 11.6 4.0 7.1 6.2 0.0 2.4 2 0 0 2 2 2 0 E10-like protein conserved region Arm PF00514.18 ETO15704.1 - 6e-60 197.1 11.3 5.1e-09 35.6 0.0 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 ETO15704.1 - 1.2e-19 70.3 0.0 0.00017 21.8 0.1 5.7 1 1 5 6 6 6 6 HEAT repeats HEAT_EZ PF13513.1 ETO15704.1 - 7.9e-19 67.5 2.9 0.00018 21.8 0.0 6.9 4 2 3 7 7 7 4 HEAT-like repeat HEAT PF02985.17 ETO15704.1 - 1.4e-07 31.0 5.2 1.1 9.4 0.0 7.5 7 1 0 7 7 7 1 HEAT repeat V-ATPase_H_N PF03224.9 ETO15704.1 - 1.9e-06 27.2 0.4 7.6e-05 21.9 0.2 2.8 2 1 0 2 2 2 1 V-ATPase subunit H IBB PF01749.15 ETO15704.1 - 2.3e-06 27.6 3.5 8.7e-06 25.8 2.5 1.9 1 0 0 1 1 1 1 Importin beta binding domain RICTOR_V PF14668.1 ETO15704.1 - 0.00056 19.7 3.8 0.086 12.7 0.1 4.7 4 2 2 6 6 6 2 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.3 ETO15704.1 - 0.0018 18.2 0.0 2.5 8.0 0.0 4.3 4 1 0 5 5 5 1 V-ATPase subunit H HEAT_PBS PF03130.11 ETO15704.1 - 0.014 15.8 4.6 71 4.3 0.0 5.8 7 1 0 7 7 7 0 PBS lyase HEAT-like repeat FolB PF02152.13 ETO15705.1 - 1.9e-23 82.7 0.0 3.1e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Dihydroneopterin aldolase Zn_ribbon_2 PF12674.2 ETO15705.1 - 0.8 10.0 4.7 0.67 10.3 1.5 1.9 2 0 0 2 2 2 0 Putative zinc ribbon domain PfkB PF00294.19 ETO15706.1 - 6.5e-53 179.8 0.2 1.6e-35 122.7 0.1 2.0 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Glycos_transf_2 PF00535.21 ETO15707.1 - 4.5e-21 75.2 0.0 1.6e-18 66.9 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 ETO15707.1 - 1.1e-08 35.2 0.0 4.8e-08 33.0 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 ETO15707.1 - 2.5e-05 23.4 0.0 3.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 ETO15707.1 - 0.15 11.3 0.0 3.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 21 Mo25 PF08569.6 ETO15708.1 - 1.8e-68 231.0 21.9 1.5e-67 228.0 15.2 2.1 1 1 0 1 1 1 1 Mo25-like UCH PF00443.24 ETO15708.1 - 5.6 5.9 7.1 7 5.6 0.4 2.4 1 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Abhydrolase_5 PF12695.2 ETO15709.1 - 4.6e-16 58.8 0.0 1e-11 44.7 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETO15709.1 - 4.8e-06 26.6 0.0 2.2e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 ETO15709.1 - 7.4e-06 25.6 0.0 1.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETO15709.1 - 0.00024 20.4 0.0 0.047 12.9 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family Tannase PF07519.6 ETO15709.1 - 0.00031 19.5 0.1 0.00058 18.6 0.1 1.4 1 0 0 1 1 1 1 Tannase and feruloyl esterase BAAT_C PF08840.6 ETO15709.1 - 0.0039 16.9 0.2 0.085 12.5 0.0 2.5 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal MIF PF01187.13 ETO15709.1 - 0.068 13.2 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Macrophage migration inhibitory factor (MIF) DUF2236 PF09995.4 ETO15711.1 - 5.9e-13 48.6 0.0 8.1e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) BUD22 PF09073.5 ETO15713.1 - 0.26 10.3 9.8 0.47 9.4 6.8 1.4 1 0 0 1 1 1 0 BUD22 CWC25 PF12542.3 ETO15713.1 - 0.29 11.5 0.2 0.29 11.5 0.1 2.6 2 1 0 2 2 2 0 Pre-mRNA splicing factor LRR_6 PF13516.1 ETO15714.1 - 3.3e-06 26.5 25.2 0.2 11.8 0.1 7.4 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.2 ETO15714.1 - 5.5e-05 22.6 10.0 0.00092 18.7 0.4 3.8 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETO15714.1 - 0.00019 21.0 13.9 2.9 8.2 0.0 6.3 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_7 PF13504.1 ETO15714.1 - 0.43 10.9 12.0 23 5.7 0.1 6.1 6 0 0 6 6 6 0 Leucine rich repeat LRR_8 PF13855.1 ETO15714.1 - 2.5 7.8 10.7 36 4.1 0.5 5.0 4 2 0 4 4 4 0 Leucine rich repeat Pyridox_oxidase PF01243.15 ETO15715.1 - 2.2e-12 46.7 0.0 7e-12 45.1 0.0 1.8 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNPOx_C PF10590.4 ETO15715.1 - 1.4e-11 43.6 0.9 3.2e-11 42.5 0.6 1.6 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.2 ETO15715.1 - 0.00052 20.2 0.0 0.0061 16.8 0.0 2.4 2 1 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase STAT_alpha PF01017.15 ETO15715.1 - 0.0077 15.9 2.2 0.0077 15.9 1.5 2.0 2 0 0 2 2 2 1 STAT protein, all-alpha domain MRP-63 PF14978.1 ETO15715.1 - 0.019 15.3 2.2 0.74 10.2 0.1 2.8 2 0 0 2 2 2 0 Mitochondrial ribosome protein 63 ECM11 PF15463.1 ETO15715.1 - 0.14 12.4 6.2 0.7 10.1 0.1 2.2 2 0 0 2 2 2 0 Extracellular mutant protein 11 Exo_endo_phos PF03372.18 ETO15716.1 - 1.2e-18 67.9 0.0 2.1e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 ETO15717.1 - 1.4e-06 27.9 1.7 1.4e-06 27.9 1.2 2.8 3 1 0 3 3 3 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 ETO15718.1 - 9.2e-08 31.6 0.2 1.2e-05 24.7 0.0 2.0 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF645 PF04875.7 ETO15718.1 - 1.6 8.4 4.4 7.6 6.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF645 Methyltransf_10 PF05971.7 ETO15719.1 - 0.073 12.2 0.5 0.08 12.0 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF890) Corona_nucleoca PF00937.13 ETO15719.1 - 0.49 9.2 7.5 0.57 9.0 5.2 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein CBP4 PF07960.6 ETO15719.1 - 1 8.9 6.5 1.4 8.5 4.5 1.1 1 0 0 1 1 1 0 CBP4 Ras PF00071.17 ETO15721.1 - 6.4e-17 61.4 0.1 1.1e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Ras family Arf PF00025.16 ETO15721.1 - 0.086 12.0 0.1 0.27 10.4 0.0 1.8 2 0 0 2 2 2 0 ADP-ribosylation factor family Peptidase_C26 PF07722.8 ETO15722.1 - 2.4e-05 23.8 0.0 8.4e-05 22.1 0.0 2.0 2 1 0 2 2 2 1 Peptidase C26 GATase PF00117.23 ETO15722.1 - 0.0065 15.9 0.0 1.9 7.8 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferase class-I WD40 PF00400.27 ETO15723.1 - 2e-76 249.3 14.9 6.6e-13 47.9 0.1 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO15723.1 - 5.9e-06 24.8 1.7 0.0032 15.8 0.2 2.7 1 1 0 2 2 2 2 Cytochrome D1 heme domain Mid2 PF04478.7 ETO15723.1 - 0.0018 17.7 2.0 0.1 12.0 0.0 3.4 3 1 1 4 4 4 1 Mid2 like cell wall stress sensor PQQ_2 PF13360.1 ETO15723.1 - 0.017 14.5 0.1 0.24 10.8 0.0 2.3 2 1 0 2 2 2 0 PQQ-like domain PD40 PF07676.7 ETO15723.1 - 0.29 10.8 3.7 6.7 6.5 0.1 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat BLUF PF04940.7 ETO15726.1 - 0.091 12.4 0.2 0.92 9.2 0.1 2.4 2 0 0 2 2 2 0 Sensors of blue-light using FAD WD40 PF00400.27 ETO15728.1 - 1.1e-09 37.8 7.5 5.1e-06 26.1 0.4 3.7 3 1 0 3 3 3 2 WD domain, G-beta repeat WD40 PF00400.27 ETO15731.1 - 4.5e-05 23.1 0.3 0.5 10.3 0.0 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat eIF2A PF08662.6 ETO15731.1 - 0.014 15.0 0.3 0.86 9.2 0.1 2.5 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO15731.1 - 0.028 14.0 0.1 3 7.6 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO15731.1 - 0.067 12.6 0.0 0.09 12.2 0.0 1.2 1 0 0 1 1 1 0 PQQ-like domain Coatomer_WDAD PF04053.9 ETO15731.1 - 0.077 11.7 0.4 0.26 10.0 0.2 1.7 1 1 1 2 2 2 0 Coatomer WD associated region Nbas_N PF15492.1 ETO15731.1 - 0.11 11.6 0.1 0.28 10.2 0.0 1.8 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 ETO15731.1 - 0.2 11.0 0.8 2.4 7.5 0.1 2.4 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature Lactamase_B PF00753.22 ETO15733.1 - 1.1e-18 67.6 0.3 1.5e-18 67.1 0.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETO15733.1 - 2.4e-05 23.9 1.2 3.3e-05 23.5 0.7 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain UN_NPL4 PF11543.3 ETO15733.1 - 0.069 13.4 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 DUF3895 PF13034.1 ETO15733.1 - 0.42 10.1 4.4 0.53 9.7 1.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3895) DUF2805 PF10985.3 ETO15734.1 - 0.027 14.4 1.7 0.033 14.1 0.0 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2805) PBP1_TM PF14812.1 ETO15734.1 - 0.091 13.0 1.9 0.17 12.1 1.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2606 PF10794.4 ETO15735.1 - 0.11 11.9 4.6 0.39 10.1 3.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2606) WD40 PF00400.27 ETO15736.1 - 1.7e-80 262.3 17.9 4e-14 51.8 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO15736.1 - 7.3e-09 35.6 0.2 0.00059 19.5 0.0 2.7 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO15736.1 - 2.5e-08 32.5 5.9 0.0056 14.8 0.1 4.8 1 1 2 5 5 5 3 Nucleoporin Nup120/160 PD40 PF07676.7 ETO15736.1 - 4.9e-07 29.2 7.7 3.5 7.3 0.0 6.7 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO15736.1 - 4e-05 23.1 0.1 0.00036 20.0 0.0 2.4 2 1 1 3 3 3 1 PQQ-like domain Nucleoporin_N PF08801.6 ETO15736.1 - 5.2e-05 22.1 11.5 0.027 13.2 0.3 4.8 1 1 1 3 3 3 3 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO15736.1 - 6.5e-05 21.3 0.9 0.6 8.3 0.0 3.5 1 1 3 4 4 4 4 Cytochrome D1 heme domain Str_synth PF03088.11 ETO15736.1 - 0.00021 21.2 0.2 12 5.9 0.0 4.8 3 1 2 5 5 5 1 Strictosidine synthase SGL PF08450.7 ETO15736.1 - 0.00037 19.9 0.1 0.023 14.0 0.0 2.4 1 1 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Proteasome_A_N PF10584.4 ETO15736.1 - 0.014 14.6 6.5 4.2 6.7 0.0 4.6 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature DUF1258 PF06869.7 ETO15736.1 - 0.064 12.3 0.4 6.5 5.7 0.0 2.9 1 1 2 4 4 4 0 Protein of unknown function (DUF1258) Vac_Fusion PF02346.11 ETO15736.1 - 0.069 12.5 0.1 7.7 6.0 0.0 3.2 3 0 0 3 3 3 0 Chordopoxvirus fusion protein BROMI PF14961.1 ETO15737.1 - 0.013 12.6 3.4 0.016 12.3 2.4 1.1 1 0 0 1 1 1 0 Broad-minded protein WAK PF08488.6 ETO15737.1 - 0.083 13.2 1.5 0.17 12.2 1.0 1.6 1 0 0 1 1 1 0 Wall-associated kinase RhoGEF PF00621.15 ETO15738.1 - 6.7e-16 58.6 0.2 6.7e-16 58.6 0.1 1.8 2 0 0 2 2 2 1 RhoGEF domain INCA1 PF15142.1 ETO15738.1 - 0.022 14.5 1.7 0.17 11.6 2.2 1.7 2 0 0 2 2 2 0 INCA1 Corona_nucleoca PF00937.13 ETO15738.1 - 2.8 6.7 10.7 1.1 8.1 5.2 1.7 1 1 1 2 2 2 0 Coronavirus nucleocapsid protein PBP1_TM PF14812.1 ETO15738.1 - 3.7 7.9 15.9 1.6 9.1 0.8 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-Di19 PF05605.7 ETO15740.1 - 0.0058 16.7 0.7 0.011 15.7 0.5 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 ETO15740.1 - 0.011 16.0 5.0 0.017 15.3 1.6 2.7 2 1 0 2 2 2 0 Zinc finger, C2H2 type DUF629 PF04780.7 ETO15740.1 - 0.02 13.4 0.8 0.02 13.4 0.5 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF629) DUF2420 PF10336.4 ETO15741.1 - 0.05 13.1 1.8 0.51 9.9 1.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2420) DUF2959 PF11172.3 ETO15742.1 - 0.0057 16.4 2.3 0.0065 16.2 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2959) Baculo_LEF-11 PF06385.7 ETO15742.1 - 0.029 14.4 1.8 0.038 14.0 1.2 1.2 1 0 0 1 1 1 0 Baculovirus LEF-11 protein RPOL_N PF14700.1 ETO15742.1 - 0.056 12.6 1.7 0.063 12.5 1.1 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal REJ PF02010.10 ETO15742.1 - 0.11 10.7 1.4 0.13 10.5 1.0 1.0 1 0 0 1 1 1 0 REJ domain Alph_Pro_TM PF09608.5 ETO15742.1 - 0.16 11.4 1.4 0.2 11.1 1.0 1.1 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) Topoisom_I_N PF02919.10 ETO15742.1 - 0.35 10.1 3.4 0.37 10.0 2.3 1.0 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment DUF2431 PF10354.4 ETO15743.1 - 5.3e-17 62.2 2.8 5.3e-17 62.2 1.9 3.0 2 2 1 3 3 3 1 Domain of unknown function (DUF2431) Ras PF00071.17 ETO15745.1 - 4.9e-26 91.0 1.9 5e-26 91.0 0.5 1.6 2 0 0 2 2 2 1 Ras family Miro PF08477.8 ETO15745.1 - 1e-09 38.9 0.1 3.9e-09 37.0 0.0 1.9 1 1 1 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 ETO15745.1 - 2.7e-06 26.9 0.2 3.9e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 ETO15745.1 - 3.7e-06 26.2 0.1 6.6e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETO15745.1 - 0.00016 20.8 0.2 0.0003 20.0 0.1 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 ETO15745.1 - 0.003 17.5 0.1 0.0053 16.6 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase PSD4 PF07631.6 ETO15745.1 - 0.11 12.8 0.5 0.89 9.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1592) RRM_6 PF14259.1 ETO15747.1 - 1.1e-26 92.6 0.3 6e-09 35.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO15747.1 - 3.7e-19 68.1 0.1 1.2e-07 31.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO15747.1 - 0.00022 21.0 0.1 0.51 10.2 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 ETO15748.1 - 0.021 14.6 0.1 0.038 13.8 0.1 1.5 1 0 0 1 1 1 0 WD domain, G-beta repeat Ole-e-6 PF09253.5 ETO15748.1 - 0.054 13.1 0.0 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 Pollen allergen ole e 6 COX5B PF01215.14 ETO15748.1 - 0.13 11.9 0.1 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb Amidase02_C PF12123.3 ETO15750.1 - 0.0026 17.3 1.6 76 3.0 0.0 6.1 7 0 0 7 7 7 2 N-acetylmuramoyl-l-alanine amidase HEAT_2 PF13646.1 ETO15751.1 - 2.9e-05 24.2 0.0 0.15 12.3 0.0 3.7 3 0 0 3 3 3 2 HEAT repeats DUF919 PF06034.6 ETO15752.1 - 0.1 12.2 0.3 0.21 11.2 0.2 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Phage_Gp23 PF10669.4 ETO15753.1 - 3.5 7.7 9.5 0.89 9.6 2.1 2.3 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) WD40 PF00400.27 ETO15754.1 - 1.5e-32 110.2 12.9 8e-11 41.3 0.0 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO15754.1 - 8.5e-08 30.7 1.1 0.00015 20.0 0.2 3.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO15754.1 - 0.0096 15.8 0.0 0.39 10.6 0.0 2.6 1 1 0 2 2 2 1 Domain of unknown function (DUF3601) RasGEF PF00617.14 ETO15755.1 - 0.0043 16.7 0.1 0.0096 15.6 0.1 1.6 1 1 0 1 1 1 1 RasGEF domain DIT1_PvcA PF05141.7 ETO15755.1 - 0.0059 15.9 0.2 0.0076 15.6 0.1 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein SSXT PF05030.7 ETO15755.1 - 0.021 14.4 0.1 0.046 13.2 0.1 1.6 1 0 0 1 1 1 0 SSXT protein (N-terminal region) RasGEF PF00617.14 ETO15756.1 - 2.2e-24 86.2 5.8 4.8e-18 65.5 1.1 2.6 3 0 0 3 3 3 2 RasGEF domain Gag_spuma PF03276.9 ETO15756.1 - 0.0031 15.9 0.1 0.004 15.5 0.1 1.1 1 0 0 1 1 1 1 Spumavirus gag protein Terminase_4 PF05119.7 ETO15756.1 - 0.093 12.8 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Phage terminase, small subunit ADK PF00406.17 ETO15760.1 - 3.6e-52 176.2 0.1 7.2e-38 129.8 0.0 2.2 1 1 1 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 ETO15760.1 - 1.3e-11 43.9 0.0 1.3e-10 40.7 0.0 2.3 1 1 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 ETO15760.1 - 4e-06 27.6 0.1 8.8e-06 26.5 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETO15760.1 - 0.00076 19.7 0.5 0.0055 17.0 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETO15760.1 - 0.00095 19.0 0.0 0.019 14.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 ETO15760.1 - 0.038 13.0 0.1 0.097 11.7 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin Glutaredoxin2_C PF04399.8 ETO15760.1 - 0.042 13.4 0.2 0.087 12.4 0.1 1.5 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain LicD PF04991.8 ETO15760.1 - 0.068 13.2 0.2 0.091 12.8 0.2 1.3 1 0 0 1 1 1 0 LicD family Sel1 PF08238.7 ETO15761.1 - 2.4e-16 59.7 0.2 9.4e-05 22.9 0.0 4.8 5 0 0 5 5 5 3 Sel1 repeat TPR_11 PF13414.1 ETO15761.1 - 5.8e-05 22.6 0.4 0.81 9.3 0.1 3.4 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 ETO15761.1 - 0.0044 16.8 0.1 24 5.1 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 ETO15761.1 - 0.013 15.6 1.4 10 6.6 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETO15761.1 - 0.052 13.8 0.3 0.24 11.7 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF249 PF03158.8 ETO15761.1 - 0.055 13.0 1.8 0.12 11.9 1.1 1.7 1 1 0 1 1 1 0 Multigene family 530 protein Ldh_1_C PF02866.13 ETO15761.1 - 0.063 13.0 0.4 0.091 12.4 0.3 1.2 1 0 0 1 1 1 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain Sel1 PF08238.7 ETO15762.1 - 4.5e-14 52.5 7.2 2.6e-06 27.8 0.1 3.2 3 0 0 3 3 3 3 Sel1 repeat TPR_6 PF13174.1 ETO15762.1 - 0.041 14.3 0.2 1.1 9.8 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETO15762.1 - 1.1 8.9 7.2 48 3.8 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat HEAT_2 PF13646.1 ETO15763.1 - 1.4e-17 63.7 0.0 1e-15 57.7 0.0 2.1 1 1 1 2 2 2 2 HEAT repeats HEAT_PBS PF03130.11 ETO15763.1 - 2.4e-08 33.6 0.0 0.00089 19.5 0.0 3.4 4 0 0 4 4 4 2 PBS lyase HEAT-like repeat HEAT PF02985.17 ETO15763.1 - 0.00048 19.9 0.0 0.021 14.8 0.0 3.1 3 0 0 3 3 3 1 HEAT repeat DUF1546 PF07571.8 ETO15763.1 - 0.0016 18.5 0.0 0.52 10.4 0.0 2.3 1 1 0 2 2 2 2 Protein of unknown function (DUF1546) HEAT_EZ PF13513.1 ETO15763.1 - 0.003 17.9 0.0 0.036 14.5 0.0 2.5 1 1 2 3 3 3 1 HEAT-like repeat Arm PF00514.18 ETO15763.1 - 0.17 11.7 0.2 0.38 10.6 0.0 1.7 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 ETO15764.1 - 4.4e-10 39.7 0.0 9.2e-10 38.6 0.0 1.5 1 1 0 1 1 1 1 HEAT repeats HEAT_PBS PF03130.11 ETO15764.1 - 7.8e-05 22.7 0.0 0.94 10.1 0.0 3.3 3 0 0 3 3 3 2 PBS lyase HEAT-like repeat DDE_Tnp_Tn3 PF01526.12 ETO15765.1 - 0.0076 14.9 0.1 0.014 14.0 0.1 1.5 1 0 0 1 1 1 1 Tn3 transposase DDE domain DUF2636 PF11120.3 ETO15766.1 - 0.038 13.4 0.4 0.1 12.1 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2636) DUF3969 PF13108.1 ETO15766.1 - 0.041 13.5 2.5 0.059 13.0 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3969) PseudoU_synth_1 PF01416.15 ETO15767.1 - 3.7e-07 30.5 1.6 3.5e-06 27.3 1.4 2.5 2 1 0 2 2 2 1 tRNA pseudouridine synthase CDC45 PF02724.9 ETO15767.1 - 0.34 8.9 8.2 0.63 8.0 5.7 1.4 1 0 0 1 1 1 0 CDC45-like protein DHC_N1 PF08385.7 ETO15768.1 - 8.9e-05 21.0 6.9 0.00037 19.0 2.4 2.5 1 1 1 2 2 2 2 Dynein heavy chain, N-terminal region 1 Lipocalin_5 PF13924.1 ETO15768.1 - 0.074 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipocalin-like domain Mst1_SARAH PF11629.3 ETO15768.1 - 0.11 12.2 1.8 8.8 6.2 0.1 2.5 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 DUF1900 PF08954.6 ETO15769.1 - 3.3e-49 165.8 0.0 4.3e-48 162.2 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF1900) WD40 PF00400.27 ETO15769.1 - 1.5e-18 65.8 4.5 1.3e-08 34.4 0.0 3.6 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO15769.1 - 0.0024 16.1 0.4 0.0044 15.2 0.0 1.5 2 0 0 2 2 2 1 Nucleoporin Nup120/160 tRNA_bind PF01588.15 ETO15770.1 - 1e-14 54.1 0.3 1.1e-13 50.8 0.2 2.2 1 1 0 1 1 1 1 Putative tRNA binding domain Anticodon_1 PF08264.8 ETO15770.1 - 0.085 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 ETO15771.1 - 1e-20 73.7 0.0 1.2e-20 73.5 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 ETO15771.1 - 5.1e-17 61.1 0.0 6.5e-17 60.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 ETO15771.1 - 1.5e-07 30.8 0.0 2e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 ETO15771.1 - 1.9e-05 23.5 0.0 2.3e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (K) tRNA-synt_1b PF00579.20 ETO15771.1 - 0.025 13.7 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) Pkinase PF00069.20 ETO15773.1 - 1.6e-32 112.7 0.0 1.8e-32 112.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO15773.1 - 9.3e-10 38.0 0.0 1.4e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO15773.1 - 0.0033 16.4 0.0 0.0047 15.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DUF3645 PF12359.3 ETO15774.1 - 0.015 14.4 0.6 0.11 11.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3645) Vfa1 PF08432.5 ETO15774.1 - 0.84 9.6 5.5 1.2 9.1 3.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Utp21 PF04192.7 ETO15775.1 - 3.1e-14 52.6 3.6 6.2e-14 51.6 2.5 1.4 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 ETO15775.1 - 1.1e-06 28.2 13.5 3e-06 26.8 0.4 4.0 5 0 0 5 5 5 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 ETO15775.1 - 0.013 15.2 0.0 0.23 11.2 0.0 2.3 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region PFEMP PF03011.10 ETO15775.1 - 0.36 11.1 8.4 0.078 13.3 3.0 1.9 1 1 1 2 2 2 0 PFEMP DBL domain BNIP2 PF12496.3 ETO15775.1 - 8.6 6.5 10.0 0.97 9.6 4.1 1.6 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DUF4577 PF15145.1 ETO15776.1 - 0.062 13.2 4.0 0.061 13.2 2.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4577) DUF3671 PF12420.3 ETO15776.1 - 1.1 9.2 15.0 1.9 8.5 10.3 1.5 1 1 0 1 1 1 0 Protein of unknown function Shisa PF13908.1 ETO15776.1 - 5.6 7.0 11.4 10 6.2 7.9 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator ASFV_J13L PF05568.6 ETO15776.1 - 7.3 6.0 10.0 10 5.5 7.0 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein NAD_Gly3P_dh_N PF01210.18 ETO15777.1 - 2.3e-44 150.9 0.1 2.9e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 ETO15777.1 - 7e-09 35.5 0.3 1.4e-08 34.6 0.2 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 3HCDH_N PF02737.13 ETO15777.1 - 1.2e-07 31.5 0.0 2.7e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 ETO15777.1 - 3.8e-07 29.6 0.1 5.5e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 ETO15777.1 - 4.5e-07 30.2 0.0 1.1e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 ETO15777.1 - 2.6e-05 24.1 0.0 6.1e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Saccharop_dh PF03435.13 ETO15777.1 - 4.6e-05 22.5 0.2 7.8e-05 21.8 0.0 1.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase GIDA PF01134.17 ETO15777.1 - 0.00046 19.1 0.0 0.0006 18.7 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 ETO15777.1 - 0.008 16.0 0.2 0.019 14.8 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 ETO15777.1 - 0.0097 15.9 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 ETO15777.1 - 0.01 15.9 0.1 0.022 14.8 0.1 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 ETO15777.1 - 0.021 14.2 0.1 0.084 12.2 0.1 2.0 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Pyr_redox PF00070.22 ETO15777.1 - 0.026 14.9 0.1 0.32 11.4 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 ETO15777.1 - 0.041 14.1 0.1 0.08 13.2 0.0 1.5 2 0 0 2 2 1 0 Putative NAD(P)-binding NmrA PF05368.8 ETO15777.1 - 0.074 12.2 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family UDPG_MGDP_dh_N PF03721.9 ETO15777.1 - 0.075 12.4 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DENN PF02141.16 ETO15779.1 - 1.9e-37 128.7 6.4 3.1e-37 128.0 4.4 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain Nop14 PF04147.7 ETO15779.1 - 5.3 4.8 15.3 0.071 11.0 5.2 1.7 2 0 0 2 2 2 0 Nop14-like family Zn_ribbon_recom PF13408.1 ETO15780.1 - 0.089 13.0 3.5 0.11 12.7 1.9 1.6 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DrsE PF02635.10 ETO15781.1 - 2.3e-08 34.1 0.0 4.1e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 DsrE/DsrF-like family Rhodanese PF00581.15 ETO15781.1 - 5.9e-07 29.8 0.1 7.8e-05 22.9 0.1 2.6 2 1 0 2 2 2 1 Rhodanese-like domain LRR_6 PF13516.1 ETO15782.1 - 0.0012 18.6 7.1 1.9 8.8 0.0 4.1 4 0 0 4 4 4 2 Leucine Rich repeat LRR_8 PF13855.1 ETO15782.1 - 0.085 12.6 4.4 1.1 9.1 0.3 3.5 3 2 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.28 ETO15782.1 - 0.14 12.2 8.9 21 5.6 0.1 5.1 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 ETO15782.1 - 0.17 12.1 10.1 4.8 7.8 0.0 4.8 5 1 0 5 5 5 0 Leucine rich repeat LRR_4 PF12799.2 ETO15782.1 - 0.58 9.8 5.8 5.6 6.7 0.1 3.8 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) 3A PF00803.13 ETO15783.1 - 0.03 13.4 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 3A/RNA2 movement protein family Helicase_C_2 PF13307.1 ETO15784.1 - 6.4e-52 175.8 0.7 1.4e-51 174.7 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 ETO15784.1 - 1e-42 145.4 14.2 1.2e-39 135.5 8.7 3.2 2 1 0 2 2 2 1 DEAD_2 AAA_22 PF13401.1 ETO15784.1 - 0.00097 19.2 0.3 2.9 8.0 0.0 3.9 3 0 0 3 3 3 1 AAA domain 7TM_GPCR_Srt PF10321.4 ETO15784.1 - 0.014 14.2 2.4 0.14 10.8 0.2 2.2 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srt cNMP_binding PF00027.24 ETO15785.1 - 2.5e-09 36.8 0.1 0.00041 20.0 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain CS PF04969.11 ETO15786.1 - 3e-10 40.5 2.5 3e-10 40.5 1.7 1.9 2 0 0 2 2 2 1 CS domain SeqA PF03925.8 ETO15786.1 - 0.077 12.6 0.1 0.077 12.6 0.1 1.7 2 1 0 2 2 2 0 SeqA protein EamA PF00892.15 ETO15786.1 - 0.22 11.5 5.2 1.4 8.9 3.4 2.0 2 0 0 2 2 2 0 EamA-like transporter family Gtr1_RagA PF04670.7 ETO15787.1 - 4.5e-18 65.2 0.0 6.5e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DNA_ligase_A_M PF01068.16 ETO15788.1 - 1.1e-55 188.1 1.1 2.4e-55 187.0 0.7 1.6 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 ETO15788.1 - 1.8e-46 158.1 0.1 3.2e-46 157.3 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 ETO15788.1 - 5.2e-23 81.2 0.0 1.1e-22 80.1 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region CDC45 PF02724.9 ETO15789.1 - 0.14 10.1 2.9 0.13 10.2 2.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Ank_2 PF12796.2 ETO15790.1 - 0.0014 18.9 0.0 0.0044 17.3 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO15790.1 - 0.0078 16.6 0.2 0.022 15.2 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Afi1 PF07792.7 ETO15791.1 - 0.016 15.2 0.1 0.025 14.6 0.1 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF3675 PF12428.3 ETO15791.1 - 0.019 15.2 0.0 6.2 7.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) Med2 PF11214.3 ETO15791.1 - 0.74 9.8 7.7 1.9 8.5 5.3 1.7 1 1 0 1 1 1 0 Mediator complex subunit 2 TMF_TATA_bd PF12325.3 ETO15795.1 - 2 8.1 19.1 3.4 7.4 2.3 4.4 3 2 1 4 4 4 0 TATA element modulatory factor 1 TATA binding Lzipper-MIP1 PF14389.1 ETO15795.1 - 2.4 8.3 18.4 0.072 13.2 2.3 3.6 4 1 1 5 5 5 0 Leucine-zipper of ternary complex factor MIP1 TACC PF05010.9 ETO15795.1 - 2.4 7.8 18.6 1.8 8.2 9.1 2.6 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) DUF4618 PF15397.1 ETO15797.1 - 4.2e-05 23.0 48.9 0.00098 18.5 11.4 3.2 1 1 2 3 3 3 2 Domain of unknown function (DUF4618) Tropomyosin_1 PF12718.2 ETO15797.1 - 0.00034 20.4 63.2 0.051 13.4 2.6 4.8 1 1 4 5 5 5 3 Tropomyosin like Baculo_PEP_C PF04513.7 ETO15797.1 - 0.00039 20.2 28.7 0.63 9.8 4.1 3.6 1 1 1 3 3 3 3 Baculovirus polyhedron envelope protein, PEP, C terminus Myosin_tail_1 PF01576.14 ETO15797.1 - 0.0032 15.2 56.6 0.039 11.6 9.2 2.8 1 1 1 2 2 2 1 Myosin tail Lebercilin PF15619.1 ETO15797.1 - 0.0086 15.5 62.1 0.25 10.7 12.8 3.7 1 1 2 3 3 3 2 Ciliary protein causing Leber congenital amaurosis disease V_ATPase_I PF01496.14 ETO15797.1 - 0.011 13.6 36.4 0.026 12.4 25.1 1.5 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Filament PF00038.16 ETO15797.1 - 0.021 14.2 53.2 0.13 11.7 36.4 2.4 1 1 0 1 1 1 0 Intermediate filament protein AAA_13 PF13166.1 ETO15797.1 - 0.041 12.3 43.2 0.049 12.0 18.8 2.2 1 1 1 2 2 2 0 AAA domain DUF869 PF05911.6 ETO15797.1 - 0.33 9.1 48.9 0.85 7.7 14.0 2.8 1 1 2 3 3 3 0 Plant protein of unknown function (DUF869) WEMBL PF05701.6 ETO15797.1 - 0.33 9.3 45.8 0.57 8.5 31.8 1.3 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Cast PF10174.4 ETO15797.1 - 0.48 8.4 53.7 0.81 7.6 37.2 1.3 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone GAS PF13851.1 ETO15797.1 - 0.7 9.0 59.2 0.4 9.8 2.8 4.0 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding FlaC_arch PF05377.6 ETO15797.1 - 0.82 9.6 27.1 1.1 9.1 0.1 6.0 4 2 3 7 7 7 0 Flagella accessory protein C (FlaC) Reo_sigmaC PF04582.7 ETO15797.1 - 0.94 8.5 15.5 5 6.2 1.7 2.9 1 1 2 3 3 3 0 Reovirus sigma C capsid protein HOOK PF05622.7 ETO15797.1 - 1.5 6.5 57.5 0.45 8.2 17.5 2.3 1 1 1 2 2 2 0 HOOK protein CENP-F_leu_zip PF10473.4 ETO15797.1 - 1.5 8.6 64.8 0.95 9.3 1.4 4.8 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.7 ETO15797.1 - 1.7 8.4 31.1 1.9 8.2 1.9 4.0 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Rootletin PF15035.1 ETO15797.1 - 3.4 7.6 58.1 0.097 12.6 5.3 3.4 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion IncA PF04156.9 ETO15797.1 - 3.4 7.2 66.3 2.7 7.5 13.0 3.2 1 1 2 3 3 3 0 IncA protein FliJ PF02050.11 ETO15797.1 - 4.8 7.2 60.7 1.8 8.6 11.0 4.1 1 1 3 4 4 4 0 Flagellar FliJ protein Pox_A_type_inc PF04508.7 ETO15797.1 - 5.2 7.1 23.9 11 6.1 0.3 6.7 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat Fib_alpha PF08702.5 ETO15797.1 - 6 6.9 46.6 1.8 8.6 10.1 4.1 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family FlpD PF02662.11 ETO15797.1 - 6.8 6.3 8.0 1 9.0 0.6 2.8 2 1 0 3 3 3 0 Methyl-viologen-reducing hydrogenase, delta subunit HALZ PF02183.13 ETO15798.1 - 0.034 13.8 5.9 0.51 10.0 4.1 2.5 1 1 0 1 1 1 0 Homeobox associated leucine zipper SET PF00856.23 ETO15798.1 - 0.077 13.2 3.1 0.19 12.0 0.0 2.9 2 2 0 2 2 2 0 SET domain Sec8_exocyst PF04048.9 ETO15799.1 - 1e-08 34.9 1.9 1.1e-07 31.6 0.1 2.4 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain BAF1_ABF1 PF04684.8 ETO15799.1 - 0.0031 16.4 0.2 0.0037 16.1 0.2 1.3 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor ER-remodelling PF14755.1 ETO15799.1 - 0.025 14.6 0.1 0.036 14.1 0.1 1.2 1 0 0 1 1 1 0 Intracellular membrane remodeller DUF4125 PF13526.1 ETO15799.1 - 0.54 9.7 6.4 0.35 10.3 2.6 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4125) Pkinase PF00069.20 ETO15800.1 - 1.5e-27 96.4 0.0 5.5e-27 94.5 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO15800.1 - 1.4e-09 37.3 0.7 5.4e-09 35.4 0.0 2.2 3 0 0 3 3 3 1 Protein tyrosine kinase DUF4404 PF14357.1 ETO15800.1 - 1.6 9.1 0.0 1.6 9.1 0.0 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4404) LIM PF00412.17 ETO15801.1 - 0.26 11.3 9.5 0.091 12.8 3.8 2.3 2 0 0 2 2 2 0 LIM domain zf-C3HC4_2 PF13923.1 ETO15801.1 - 2.6 8.1 13.2 6.2 6.9 9.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Exo_endo_phos PF03372.18 ETO15802.1 - 0.0009 19.2 0.1 0.65 9.8 0.0 2.1 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family NHL PF01436.16 ETO15806.1 - 0.041 13.8 0.1 4.9 7.3 0.0 3.0 3 0 0 3 3 3 0 NHL repeat PX PF00787.19 ETO15807.1 - 6.2e-11 42.0 0.3 1.2e-10 41.1 0.2 1.5 1 0 0 1 1 1 1 PX domain RRM_6 PF14259.1 ETO15807.1 - 0.00026 20.8 0.0 0.00085 19.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO15807.1 - 0.0035 16.9 0.1 0.0095 15.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO15807.1 - 0.062 13.1 0.1 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-TRAF PF02176.13 ETO15808.1 - 2.9e-06 27.5 2.0 2.9e-06 27.5 1.4 2.5 2 0 0 2 2 2 1 TRAF-type zinc finger TPT PF03151.11 ETO15810.1 - 3.9e-05 23.3 12.3 5.6e-05 22.8 8.5 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family DUF3708 PF12501.3 ETO15810.1 - 0.019 14.8 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter IncA PF04156.9 ETO15810.1 - 0.028 13.9 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 IncA protein BAF1_ABF1 PF04684.8 ETO15810.1 - 0.065 12.0 6.3 0.087 11.6 4.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor EamA PF00892.15 ETO15810.1 - 0.59 10.1 14.3 0.8 9.7 9.9 1.1 1 0 0 1 1 1 0 EamA-like transporter family ubiquitin PF00240.18 ETO15812.1 - 6.9e-06 25.3 0.1 1.8e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 ETO15812.1 - 0.0017 18.5 0.1 0.0017 18.5 0.1 2.7 2 2 0 2 2 2 1 Ubiquitin-like domain DUF1777 PF08648.7 ETO15812.1 - 1.1 9.0 99.3 0.014 15.1 38.4 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1777) CytochromB561_N PF09786.4 ETO15812.1 - 2 6.8 22.8 2.8 6.2 15.8 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Peptidase_S64 PF08192.6 ETO15812.1 - 5.8 5.1 31.7 7.2 4.8 22.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 PRA1 PF03208.14 ETO15813.1 - 0.067 12.5 0.2 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 PRA1 family protein Ribosomal_S25 PF03297.10 ETO15814.1 - 5.5e-25 87.4 5.9 5.5e-25 87.4 4.1 5.4 1 1 2 3 3 3 1 S25 ribosomal protein HTH_DeoR PF08220.7 ETO15814.1 - 0.015 14.8 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain dCMP_cyt_deam_1 PF00383.17 ETO15815.1 - 8.2e-09 35.0 0.6 1.6e-08 34.1 0.4 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF2681 PF10883.3 ETO15816.1 - 0.77 10.0 4.6 1.4 9.1 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) Ran_BP1 PF00638.13 ETO15817.1 - 3.4e-09 36.8 1.3 9e-09 35.4 0.0 2.3 3 0 0 3 3 3 1 RanBP1 domain DUF4597 PF15366.1 ETO15817.1 - 0.017 14.6 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) WD40 PF00400.27 ETO15818.1 - 2.5e-68 223.6 21.8 3e-12 45.9 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO15818.1 - 2.7e-07 29.1 5.4 0.21 9.6 0.1 4.2 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO15818.1 - 2.3e-05 22.8 0.4 0.032 12.5 0.1 3.1 2 1 1 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO15818.1 - 5.9e-05 21.9 10.9 0.12 11.1 0.3 4.1 1 1 3 4 4 4 3 Nup133 N terminal like DUF1258 PF06869.7 ETO15818.1 - 0.00086 18.4 2.3 0.15 11.1 0.1 2.9 2 2 1 3 3 3 2 Protein of unknown function (DUF1258) Nbas_N PF15492.1 ETO15818.1 - 0.0045 16.1 1.4 3.9 6.4 0.0 3.3 1 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 ETO15818.1 - 0.033 13.6 0.0 1.1 8.7 0.0 2.5 1 1 1 2 2 2 0 PQQ-like domain LRR_5 PF13306.1 ETO15818.1 - 0.045 13.4 0.2 8 6.1 0.0 2.7 2 1 0 2 2 2 0 Leucine rich repeats (6 copies) Cuticle_1 PF08140.6 ETO15818.1 - 0.14 12.0 0.0 66 3.4 0.0 3.6 3 0 0 3 3 3 0 Crustacean cuticle protein repeat PD40 PF07676.7 ETO15818.1 - 0.9 9.2 3.1 3.9 7.2 0.1 3.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF3342 PF11822.3 ETO15819.1 - 0.0069 15.5 0.3 0.0071 15.5 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) DUF2309 PF10070.4 ETO15819.1 - 0.012 13.7 0.1 0.014 13.5 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) MRP-63 PF14978.1 ETO15819.1 - 0.05 14.0 1.0 3.1 8.3 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial ribosome protein 63 Lyase_catalyt PF09093.6 ETO15820.1 - 0.011 14.6 0.2 0.014 14.3 0.2 1.1 1 0 0 1 1 1 0 Lyase, catalytic DUF3399 PF11879.3 ETO15821.1 - 0.087 13.0 0.1 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3399) WD40 PF00400.27 ETO15822.1 - 8e-05 22.3 0.1 0.85 9.6 0.1 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat Daxx PF03344.10 ETO15822.1 - 0.007 14.9 20.7 0.0097 14.4 14.4 1.1 1 0 0 1 1 1 1 Daxx Family Hid1 PF12722.2 ETO15822.1 - 7.2 4.1 23.6 9.7 3.7 16.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Mcp5_PH PF12814.2 ETO15823.1 - 0.036 13.9 0.2 0.058 13.3 0.1 1.3 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology RRP14 PF15459.1 ETO15823.1 - 1.3 9.1 5.7 18 5.4 0.1 2.5 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 DUF904 PF06005.7 ETO15824.1 - 0.015 15.5 7.0 0.025 14.8 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) IncA PF04156.9 ETO15824.1 - 0.033 13.7 5.4 0.032 13.8 3.8 1.1 1 0 0 1 1 1 0 IncA protein GlutR_dimer PF00745.15 ETO15824.1 - 0.081 12.8 2.7 0.11 12.4 1.9 1.3 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain Caldesmon PF02029.10 ETO15825.1 - 0.016 13.6 31.9 0.021 13.2 22.1 1.2 1 0 0 1 1 1 0 Caldesmon Utp14 PF04615.8 ETO15825.1 - 0.03 12.5 33.3 0.033 12.3 23.1 1.0 1 0 0 1 1 1 0 Utp14 protein Daxx PF03344.10 ETO15825.1 - 0.072 11.5 35.8 0.085 11.3 24.8 1.0 1 0 0 1 1 1 0 Daxx Family GAGA_bind PF06217.7 ETO15825.1 - 0.12 12.3 19.2 0.2 11.6 13.3 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family MIP-T3 PF10243.4 ETO15825.1 - 0.18 10.2 40.5 0.2 10.1 28.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CDC27 PF09507.5 ETO15825.1 - 0.2 10.8 38.6 0.23 10.6 26.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nop14 PF04147.7 ETO15825.1 - 0.24 9.2 29.2 0.27 9.1 20.2 1.1 1 0 0 1 1 1 0 Nop14-like family GBP_C PF02841.9 ETO15825.1 - 0.38 9.8 29.2 0.5 9.5 20.2 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Spore_YhcN_YlaJ PF09580.5 ETO15825.1 - 0.5 10.4 15.0 0.64 10.1 10.4 1.4 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Asp-B-Hydro_N PF05279.6 ETO15825.1 - 0.72 9.6 32.3 0.86 9.4 22.4 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Lin-8 PF03353.10 ETO15825.1 - 0.82 8.8 26.4 0.97 8.6 18.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Suf PF05843.9 ETO15825.1 - 0.94 9.1 14.5 0.97 9.1 10.1 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Raftlin PF15250.1 ETO15825.1 - 0.97 7.8 17.8 1.1 7.6 12.3 1.2 1 0 0 1 1 1 0 Raftlin GET2 PF08690.5 ETO15825.1 - 1.8 7.7 18.6 2.1 7.5 12.9 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Parvo_coat PF00740.13 ETO15825.1 - 1.8 7.4 16.0 2 7.2 11.1 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DHHW PF14286.1 ETO15825.1 - 1.8 7.7 16.9 2.4 7.3 11.7 1.3 1 0 0 1 1 1 0 DHHW protein Hid1 PF12722.2 ETO15825.1 - 1.9 6.0 23.1 2.1 5.9 16.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AvrE PF11725.3 ETO15825.1 - 2.8 4.8 23.0 3.2 4.6 16.0 1.0 1 0 0 1 1 1 0 Pathogenicity factor RNA_pol_Rpb1_1 PF04997.7 ETO15825.1 - 3.1 6.9 17.1 3.5 6.7 11.9 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 SAPS PF04499.10 ETO15825.1 - 3.1 6.3 22.6 3.7 6.0 15.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Gag_spuma PF03276.9 ETO15825.1 - 3.3 5.9 20.9 3.8 5.7 14.5 1.1 1 0 0 1 1 1 0 Spumavirus gag protein CobT PF06213.7 ETO15825.1 - 3.9 6.5 31.3 5.2 6.1 21.7 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Neur_chan_memb PF02932.11 ETO15825.1 - 5 6.9 17.0 5.9 6.6 11.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SDA1 PF05285.7 ETO15825.1 - 5.1 6.2 35.8 6.3 5.9 24.8 1.1 1 0 0 1 1 1 0 SDA1 Ycf1 PF05758.7 ETO15825.1 - 6.3 4.3 26.2 7.1 4.2 18.1 1.1 1 0 0 1 1 1 0 Ycf1 DUF2201_N PF13203.1 ETO15825.1 - 6.9 5.7 21.1 8.9 5.3 14.7 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Prok-E2_A PF14457.1 ETO15826.1 - 0.018 14.5 0.2 0.031 13.7 0.1 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family A DivIC PF04977.10 ETO15826.1 - 0.032 13.7 2.4 0.032 13.7 1.7 2.4 3 0 0 3 3 3 0 Septum formation initiator EB1 PF03271.12 ETO15828.1 - 2.5e-06 27.4 1.5 7.3e-06 25.9 1.0 1.8 1 0 0 1 1 1 1 EB1-like C-terminal motif Presenilin PF01080.12 ETO15828.1 - 2 7.1 5.0 5.8 5.6 0.7 2.1 2 0 0 2 2 2 0 Presenilin MutS_V PF00488.16 ETO15829.1 - 1.4e-83 279.9 0.0 2.3e-83 279.2 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 ETO15829.1 - 3.1e-32 112.0 0.0 1.5e-30 106.5 0.0 2.3 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.15 ETO15829.1 - 4.8e-30 103.9 0.0 1.2e-29 102.6 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 ETO15829.1 - 3.7e-09 36.7 0.0 3.2e-08 33.7 0.0 2.4 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 ETO15829.1 - 8.6e-06 25.8 0.2 8.6e-06 25.8 0.1 2.4 2 0 0 2 2 2 1 MutS family domain IV UCH PF00443.24 ETO15830.1 - 4.5e-22 78.4 0.7 5.7e-22 78.1 0.5 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO15830.1 - 9.8e-16 58.0 0.5 1.2e-15 57.7 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Herpes_IE68 PF02479.11 ETO15830.1 - 0.062 12.4 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus immediate early protein Iso_dh PF00180.15 ETO15832.1 - 2.4e-05 23.4 0.0 3.2e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1115 PF06544.7 ETO15833.1 - 2.7e-09 36.7 0.2 3.4e-09 36.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) eIF-3c_N PF05470.7 ETO15834.1 - 9.4e-10 37.2 14.4 9.4e-10 37.2 10.0 2.3 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Ribosomal_L2_C PF03947.13 ETO15835.1 - 5.8e-38 129.6 0.6 8e-38 129.1 0.4 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 ETO15835.1 - 1.6e-08 34.3 0.0 7.8e-08 32.1 0.0 2.1 2 1 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain DUF2671 PF10877.3 ETO15835.1 - 0.053 13.3 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2671) RasGAP_C PF03836.10 ETO15836.1 - 0.0098 15.5 3.9 1 9.0 1.0 2.5 2 0 0 2 2 2 2 RasGAP C-terminus Tubulin_C PF03953.12 ETO15839.1 - 3.8e-50 169.1 0.1 5.9e-50 168.5 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 ETO15839.1 - 1.2e-09 38.3 0.1 2.7e-09 37.1 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Cytochrom_B_N PF00033.14 ETO15840.1 - 0.0087 15.4 1.7 0.025 13.9 1.2 1.7 1 1 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Ni_hydr_CYTB PF01292.15 ETO15840.1 - 0.13 11.6 3.6 0.047 13.0 0.6 1.8 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 Cytochrom_B_N_2 PF13631.1 ETO15840.1 - 0.17 11.6 0.1 0.17 11.6 0.0 2.7 3 0 0 3 3 3 0 Cytochrome b(N-terminal)/b6/petB DctQ PF04290.7 ETO15840.1 - 0.92 9.2 7.1 0.071 12.8 0.9 1.9 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF3825 PF12873.2 ETO15842.1 - 0.012 14.7 0.9 0.013 14.6 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) Hom_end_hint PF05203.11 ETO15843.1 - 0.096 12.4 1.7 0.11 12.1 0.1 1.9 2 0 0 2 2 2 0 Hom_end-associated Hint Myb_CC_LHEQLE PF14379.1 ETO15843.1 - 0.13 11.9 2.7 0.24 11.0 1.9 1.4 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif DivIC PF04977.10 ETO15843.1 - 1.2 8.6 5.3 1.1 8.7 2.5 1.8 2 0 0 2 2 2 0 Septum formation initiator Urease_alpha PF00449.15 ETO15844.1 - 0.026 14.6 0.1 0.035 14.2 0.0 1.2 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain Kunitz_legume PF00197.13 ETO15844.1 - 0.13 11.8 1.8 0.16 11.4 1.3 1.1 1 0 0 1 1 1 0 Trypsin and protease inhibitor FHA PF00498.21 ETO15845.1 - 7.4e-14 51.6 0.5 1.7e-13 50.4 0.1 1.7 2 0 0 2 2 2 1 FHA domain ThiS PF02597.15 ETO15845.1 - 0.057 13.8 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 ThiS family Pkinase PF00069.20 ETO15846.1 - 2.2e-30 105.7 0.1 3.5e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO15846.1 - 3.1e-14 52.6 0.0 4.2e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO15846.1 - 0.00022 20.2 0.0 0.00038 19.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Vps54 PF07928.7 ETO15847.1 - 0.021 14.9 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 Vps54-like protein DUF913 PF06025.7 ETO15849.1 - 0.06 12.0 0.5 0.077 11.7 0.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Moulting_cycle PF04870.11 ETO15849.1 - 0.1 11.6 12.1 0.14 11.1 8.4 1.1 1 0 0 1 1 1 0 Moulting cycle AAA_11 PF13086.1 ETO15849.1 - 0.26 10.8 5.0 0.37 10.3 3.5 1.2 1 0 0 1 1 1 0 AAA domain HTH_AsnC-type PF13404.1 ETO15850.1 - 0.014 14.9 0.1 0.027 13.9 0.1 1.4 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Avl9 PF09794.4 ETO15850.1 - 0.054 11.9 0.1 0.067 11.6 0.1 1.1 1 0 0 1 1 1 0 Transport protein Avl9 Peptidase_M1 PF01433.15 ETO15851.1 - 3.8e-47 161.2 2.3 4.4e-47 161.0 1.6 1.1 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 ETO15851.1 - 2.6e-18 66.3 0.2 3.5e-18 65.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase MA superfamily DUF2265 PF10023.4 ETO15851.1 - 0.0041 16.2 0.0 0.0073 15.4 0.0 1.4 1 0 0 1 1 1 1 Predicted aminopeptidase (DUF2265) BSP PF04450.7 ETO15851.1 - 0.067 12.6 0.1 0.15 11.4 0.1 1.5 1 1 0 1 1 1 0 Peptidase of plants and bacteria SprT-like PF10263.4 ETO15851.1 - 0.15 11.6 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 SprT-like family Peptidase_M61 PF05299.7 ETO15851.1 - 0.16 11.9 1.1 3.5 7.6 0.8 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase DUF4048 PF13257.1 ETO15853.1 - 0.088 12.4 6.5 0.13 11.8 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4048) FAM196 PF15265.1 ETO15853.1 - 0.63 9.2 10.9 0.73 9.0 7.5 1.0 1 0 0 1 1 1 0 FAM196 family MFMR PF07777.6 ETO15853.1 - 1.2 8.9 8.5 2 8.2 5.9 1.3 1 0 0 1 1 1 0 G-box binding protein MFMR PT PF04886.7 ETO15855.1 - 3e-17 61.6 134.4 8e-05 21.8 9.0 7.4 2 2 3 5 5 5 4 PT repeat TBCC PF07986.7 ETO15856.1 - 6.2e-29 99.8 1.9 7.2e-19 67.3 0.1 2.1 2 0 0 2 2 2 2 Tubulin binding cofactor C DUF1430 PF07242.6 ETO15856.1 - 0.031 14.3 0.3 0.046 13.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1430) PCEMA1 PF07418.6 ETO15856.1 - 0.035 13.4 0.1 0.045 13.1 0.1 1.1 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 ETRAMP PF09716.5 ETO15856.1 - 0.035 14.0 0.9 0.053 13.4 0.6 1.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) tRNA-synt_1e PF01406.14 ETO15857.1 - 1.8e-11 43.7 1.9 2.6e-11 43.1 1.2 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1c PF00749.16 ETO15857.1 - 0.027 13.1 0.0 0.027 13.1 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain TPD52 PF04201.10 ETO15857.1 - 0.063 13.0 2.5 0.097 12.3 1.7 1.2 1 0 0 1 1 1 0 Tumour protein D52 family G-alpha PF00503.15 ETO15859.1 - 1.3e-10 40.5 0.1 2e-06 26.7 0.0 2.9 1 1 1 2 2 2 2 G-protein alpha subunit Mem_trans PF03547.13 ETO15860.1 - 5.9 5.0 5.7 1.1e+03 -2.4 0.5 1.8 1 1 1 2 2 2 0 Membrane transport protein p450 PF00067.17 ETO15861.1 - 1.4e-50 172.1 0.0 1.6e-50 172.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 ETO15862.1 - 1.8e-08 33.3 0.5 2.1e-08 33.1 0.4 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hint PF01079.15 ETO15863.1 - 1.6e-08 34.0 0.0 2.8e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Hint module PT-HINT PF07591.6 ETO15863.1 - 9.7e-07 28.7 0.3 3.7e-06 26.8 0.2 2.1 1 1 0 1 1 1 1 Pretoxin HINT domain AXH PF08517.7 ETO15863.1 - 0.009 16.1 0.0 0.025 14.7 0.0 1.8 1 1 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) Asp_decarbox PF02261.11 ETO15863.1 - 0.01 15.4 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 0 Aspartate decarboxylase DUF4202 PF13875.1 ETO15863.1 - 0.021 14.4 0.1 0.036 13.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4202) Zn_Tnp_IS1595 PF12760.2 ETO15863.1 - 0.18 11.6 7.0 0.034 13.9 2.0 2.0 2 0 0 2 2 2 0 Transposase zinc-ribbon domain PI3K_rbd PF00794.13 ETO15864.1 - 2.1e-05 24.3 0.2 5.3e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain Band_3_cyto PF07565.8 ETO15865.1 - 0.065 12.7 1.5 0.093 12.2 1.0 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF3987 PF13148.1 ETO15865.1 - 0.67 8.4 5.2 0.71 8.3 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) TP53IP5 PF15331.1 ETO15865.1 - 1.4 8.7 13.6 2.5 7.9 0.0 2.1 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 DUF3408 PF11888.3 ETO15865.1 - 2.6 8.0 12.3 4 7.3 8.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) NARP1 PF12569.3 ETO15865.1 - 2.6 6.7 14.8 2.7 6.6 10.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3451 PF11933.3 ETO15865.1 - 3.9 7.2 14.6 5.1 6.8 10.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3451) Fez1 PF06818.10 ETO15866.1 - 0.011 15.7 11.1 0.016 15.1 7.7 1.2 1 0 0 1 1 1 0 Fez1 Flagellar_rod PF05149.7 ETO15866.1 - 0.018 14.2 7.6 0.024 13.8 5.3 1.3 1 0 0 1 1 1 0 Paraflagellar rod protein Bcr-Abl_Oligo PF09036.5 ETO15866.1 - 0.029 14.3 4.5 1 9.3 0.8 2.5 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Flagellin_N PF00669.15 ETO15866.1 - 0.065 13.0 8.1 0.12 12.1 5.3 1.8 1 1 0 1 1 1 0 Bacterial flagellin N-terminal helical region BCAS2 PF05700.6 ETO15866.1 - 0.14 11.5 9.3 0.23 10.8 6.3 1.5 1 1 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) APG6 PF04111.7 ETO15866.1 - 0.16 11.0 10.1 0.22 10.5 7.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 FemAB PF02388.11 ETO15866.1 - 0.45 9.1 9.2 0.37 9.4 5.7 1.3 1 1 0 1 1 1 0 FemAB family CCDC-167 PF15188.1 ETO15866.1 - 1 9.3 9.9 4.1 7.4 6.6 2.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 TPR_MLP1_2 PF07926.7 ETO15866.1 - 1.1 9.0 17.1 2.1 8.1 10.6 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2443 PF10398.4 ETO15866.1 - 1.5 8.7 4.8 1 9.2 0.7 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2443) DUF2203 PF09969.4 ETO15866.1 - 2.5 8.3 6.6 2.1 8.5 3.2 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF342 PF03961.8 ETO15866.1 - 2.7 6.3 12.2 3.6 5.8 8.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 ETO15866.1 - 2.7 5.7 6.5 3 5.5 4.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4164 PF13747.1 ETO15866.1 - 3 8.0 15.8 2.2 8.4 1.3 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) FlxA PF14282.1 ETO15866.1 - 3.1 7.7 14.6 5.7 6.9 8.2 2.3 1 1 1 2 2 2 0 FlxA-like protein COMP PF11598.3 ETO15866.1 - 5 7.2 6.4 9.1 6.4 1.7 2.6 2 1 0 2 2 1 0 Cartilage oligomeric matrix protein DUF1049 PF06305.6 ETO15866.1 - 6.6 6.2 10.2 0.44 10.0 0.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1049) Wbp11 PF09429.5 ETO15866.1 - 7 6.7 19.8 1.4 8.9 8.6 2.6 2 1 0 2 2 2 0 WW domain binding protein 11 Spc7 PF08317.6 ETO15866.1 - 7.1 5.1 17.0 14 4.1 11.8 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.4 ETO15866.1 - 8.4 5.2 12.4 6.8 5.5 7.9 1.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4140 PF13600.1 ETO15866.1 - 9.9 6.6 12.0 7.5 7.0 0.2 3.0 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) Spindle_Spc25 PF08234.7 ETO15867.1 - 3e-15 55.9 1.0 5.1e-15 55.2 0.1 1.9 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 EzrA PF06160.7 ETO15867.1 - 0.0083 14.3 9.0 0.4 8.8 3.2 2.1 2 0 0 2 2 2 2 Septation ring formation regulator, EzrA FliJ PF02050.11 ETO15867.1 - 0.021 14.8 1.5 0.021 14.8 1.0 2.9 2 1 1 3 3 3 0 Flagellar FliJ protein Dehydratase_MU PF02288.10 ETO15867.1 - 0.038 13.7 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 Dehydratase medium subunit Pollen_Ole_e_I PF01190.12 ETO15867.1 - 0.054 13.3 0.1 0.077 12.8 0.1 1.2 1 0 0 1 1 1 0 Pollen proteins Ole e I like DivIVA PF05103.8 ETO15867.1 - 0.096 12.7 5.7 0.79 9.7 1.3 2.1 2 0 0 2 2 2 0 DivIVA protein DUF2730 PF10805.3 ETO15867.1 - 0.28 10.9 3.1 0.19 11.4 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) EMP24_GP25L PF01105.19 ETO15867.1 - 0.57 9.8 4.5 0.5 10.0 0.7 2.0 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Prefoldin_2 PF01920.15 ETO15867.1 - 0.78 9.5 11.6 0.51 10.1 2.3 3.0 2 1 0 2 2 2 0 Prefoldin subunit Spectrin PF00435.16 ETO15867.1 - 0.91 9.8 6.3 9.5 6.5 1.7 2.6 2 1 0 2 2 2 0 Spectrin repeat Syntaxin-6_N PF09177.6 ETO15867.1 - 1.1 9.7 6.7 23 5.4 1.9 2.9 2 1 0 2 2 2 0 Syntaxin 6, N-terminal GAS PF13851.1 ETO15867.1 - 1.8 7.7 12.3 4.5 6.4 3.4 2.5 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding GrpE PF01025.14 ETO15867.1 - 2.3 7.7 8.0 0.86 9.1 1.0 2.3 2 1 0 2 2 2 0 GrpE OmpH PF03938.9 ETO15867.1 - 3.7 7.4 10.1 1.3 8.9 2.6 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF342 PF03961.8 ETO15867.1 - 7.5 4.8 8.7 6.9 4.9 2.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF4131 PF13567.1 ETO15868.1 - 0.0028 17.0 0.9 0.0052 16.2 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) Pox_E10 PF04805.7 ETO15870.1 - 0.0007 19.0 4.3 0.0007 19.0 3.0 2.6 1 1 2 3 3 3 1 E10-like protein conserved region Noelin-1 PF12308.3 ETO15871.1 - 0.047 13.4 1.3 0.082 12.7 0.9 1.4 1 1 0 1 1 1 0 Neurogenesis glycoprotein DUF3416 PF11896.3 ETO15871.1 - 0.2 11.6 1.6 0.38 10.6 1.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3416) FH2 PF02181.18 ETO15872.1 - 4.4e-15 55.4 0.4 8.6e-15 54.4 0.0 1.7 2 0 0 2 2 2 1 Formin Homology 2 Domain bZIP_1 PF00170.16 ETO15872.1 - 0.00081 19.2 3.8 0.0031 17.4 2.6 2.1 1 0 0 1 1 1 1 bZIP transcription factor Menin PF05053.8 ETO15872.1 - 4.7 5.2 10.9 8.8 4.3 7.6 1.5 1 0 0 1 1 1 0 Menin DivIC PF04977.10 ETO15872.1 - 6.4 6.3 8.1 0.29 10.6 0.7 2.4 2 0 0 2 2 2 0 Septum formation initiator RPEL PF02755.10 ETO15873.1 - 0.0006 19.0 5.0 0.0013 17.9 3.4 1.6 1 0 0 1 1 1 1 RPEL repeat Sdh_cyt PF01127.17 ETO15874.1 - 1.2e-05 25.1 4.4 1.2e-05 25.1 3.0 2.7 3 0 0 3 3 3 2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF1691 PF07950.6 ETO15874.1 - 0.3 11.0 2.7 0.25 11.2 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1691) Ni_hydr_CYTB PF01292.15 ETO15874.1 - 1 8.7 11.7 0.12 11.7 0.8 2.9 2 2 1 3 3 3 0 Prokaryotic cytochrome b561 Cytochrom_B_N PF00033.14 ETO15874.1 - 8.2 5.7 14.5 0.38 10.0 2.7 3.5 2 2 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB WD40 PF00400.27 ETO15875.1 - 9e-80 259.9 24.5 6.2e-14 51.2 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO15875.1 - 7.4e-13 48.6 0.1 2.1e-06 27.6 0.0 3.4 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO15875.1 - 2.1e-06 26.1 10.6 0.00081 17.6 0.1 4.2 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO15875.1 - 2.6e-05 22.6 0.9 0.0067 14.7 0.0 3.1 2 1 1 3 3 3 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO15875.1 - 0.00091 18.7 0.5 0.011 15.2 0.3 2.7 1 1 2 3 3 3 1 PQQ-like domain Nbas_N PF15492.1 ETO15875.1 - 0.0023 17.1 2.2 2.5 7.1 0.0 3.9 2 1 3 5 5 5 1 Neuroblastoma-amplified sequence, N terminal DPPIV_N PF00930.16 ETO15875.1 - 0.018 13.6 0.0 0.57 8.7 0.0 2.6 1 1 1 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.7 ETO15875.1 - 0.069 12.8 10.4 4.5 7.0 0.2 5.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Ricin_B_lectin PF00652.17 ETO15875.1 - 0.08 12.9 2.6 0.15 12.0 0.4 2.5 3 1 0 3 3 3 0 Ricin-type beta-trefoil lectin domain B_lectin PF01453.19 ETO15875.1 - 0.096 12.5 5.0 0.4 10.5 1.0 2.9 2 1 1 3 3 3 0 D-mannose binding lectin PLD_C PF12357.3 ETO15875.1 - 0.12 11.9 0.0 38 3.9 0.0 4.0 4 1 0 4 4 4 0 Phospholipase D C terminal Gmad1 PF10647.4 ETO15875.1 - 0.13 11.6 0.1 0.65 9.3 0.0 2.2 2 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain WD40 PF00400.27 ETO15876.1 - 6.3e-39 130.4 6.2 1.6e-14 53.1 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO15876.1 - 0.00046 19.0 2.9 0.23 10.1 0.2 2.5 1 1 2 3 3 3 2 Nup133 N terminal like PD40 PF07676.7 ETO15876.1 - 0.00068 19.2 0.1 1.7 8.4 0.0 3.0 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO15876.1 - 0.00082 17.6 0.1 0.19 9.8 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO15876.1 - 0.00094 18.7 0.1 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 PQQ-like domain BBS2_Mid PF14783.1 ETO15876.1 - 0.012 15.4 0.2 0.15 11.8 0.1 2.5 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Coatomer_WDAD PF04053.9 ETO15876.1 - 0.018 13.8 0.1 0.019 13.7 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region DUF4221 PF13970.1 ETO15876.1 - 0.035 13.4 0.0 0.13 11.5 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4221) MecA_N PF05223.6 ETO15877.1 - 0.063 13.3 8.7 0.056 13.5 3.9 2.1 2 0 0 2 2 2 0 NTF2-like N-terminal transpeptidase domain RR_TM4-6 PF06459.7 ETO15877.1 - 0.11 12.4 7.8 0.021 14.7 3.3 1.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Lumazine_bd PF12870.2 ETO15877.1 - 0.94 9.5 9.7 0.22 11.5 4.2 1.7 2 0 0 2 2 2 0 Lumazine-binding domain AUX_IAA PF02309.11 ETO15877.1 - 8.4 6.0 16.2 0.078 12.7 5.6 1.7 2 1 0 2 2 2 0 AUX/IAA family Yae1_N PF09811.4 ETO15879.1 - 0.017 14.6 6.4 0.034 13.6 4.4 1.5 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Pkinase_C PF00433.19 ETO15880.1 - 0.05 14.1 6.0 0.45 11.0 4.1 2.2 1 1 0 1 1 1 0 Protein kinase C terminal domain PBP_sp32 PF07222.7 ETO15881.1 - 6.3 5.8 8.5 15 4.6 5.9 1.7 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Ribosomal_60s PF00428.14 ETO15881.1 - 6.6 7.1 12.3 14 6.1 8.5 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DDE_3 PF13358.1 ETO15882.1 - 1.4e-12 47.6 0.2 1.6e-12 47.3 0.2 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease COG6 PF06419.6 ETO15882.1 - 0.018 13.1 0.1 0.02 13.0 0.0 1.0 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 LacAB_rpiB PF02502.13 ETO15882.1 - 0.088 12.4 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribose/Galactose Isomerase DUF3896 PF13035.1 ETO15882.1 - 4.6 7.3 7.1 1.7 8.7 2.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) Ion_trans PF00520.26 ETO15883.1 - 1.1e-69 233.7 49.0 1.6e-32 112.4 5.0 4.5 5 0 0 5 5 5 4 Ion transport protein PKD_channel PF08016.7 ETO15883.1 - 1.2e-05 23.9 40.5 0.0003 19.3 8.5 5.7 4 2 2 6 6 6 4 Polycystin cation channel ISK_Channel PF02060.10 ETO15883.1 - 0.045 13.3 0.3 0.43 10.1 0.0 2.8 3 0 0 3 3 3 0 Slow voltage-gated potassium channel DUF3989 PF13150.1 ETO15883.1 - 0.063 12.7 6.8 3.2 7.2 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3989) Na_trans_assoc PF06512.8 ETO15883.1 - 0.11 12.4 0.0 0.11 12.4 0.0 2.8 3 0 0 3 3 3 0 Sodium ion transport-associated Nsp3_PL2pro PF12124.3 ETO15884.1 - 0.026 14.0 0.3 0.32 10.5 0.1 2.3 2 0 0 2 2 2 0 Coronavirus polyprotein cleavage domain DUF2621 PF11084.3 ETO15885.1 - 0.028 14.1 0.4 2.4 7.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2621) OSCP PF00213.13 ETO15885.1 - 0.3 10.9 3.7 3.9 7.3 0.2 3.2 3 0 0 3 3 3 0 ATP synthase delta (OSCP) subunit MIP-T3 PF10243.4 ETO15886.1 - 3 6.2 89.3 0.54 8.6 53.5 2.0 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 HSP70 PF00012.15 ETO15887.1 - 1.3e-07 29.9 0.0 0.0018 16.2 0.0 2.3 1 1 1 2 2 2 2 Hsp70 protein Actin PF00022.14 ETO15887.1 - 0.0069 14.8 0.7 0.43 8.9 0.1 2.3 2 0 0 2 2 2 2 Actin DUF2714 PF10896.3 ETO15888.1 - 0.01 15.6 0.2 0.018 14.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2714) XS PF03468.9 ETO15888.1 - 0.096 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 XS domain LVIVD PF08309.6 ETO15890.1 - 2e-48 161.1 38.1 5.9e-06 25.1 0.2 12.9 12 1 1 13 13 13 11 LVIVD repeat He_PIG PF05345.7 ETO15890.1 - 8.9e-20 70.4 13.0 9.8e-07 28.7 1.4 6.0 5 0 0 5 5 5 4 Putative Ig domain DUF4200 PF13863.1 ETO15890.1 - 1.6e-08 34.5 16.7 1.6e-08 34.5 11.6 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF4200) Pkinase PF00069.20 ETO15891.1 - 4.2e-12 45.7 0.1 4.2e-12 45.7 0.1 2.4 2 2 0 2 2 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO15891.1 - 2.7e-08 33.2 0.8 5.9e-08 32.0 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase FAM60A PF15396.1 ETO15891.1 - 0.011 15.5 6.8 0.014 15.1 4.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Ndc1_Nup PF09531.5 ETO15891.1 - 0.034 12.5 5.4 0.033 12.6 3.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAM220 PF15487.1 ETO15891.1 - 0.067 12.5 11.3 0.091 12.1 7.8 1.1 1 0 0 1 1 1 0 FAM220 family Sec62 PF03839.11 ETO15891.1 - 0.2 11.0 7.3 0.29 10.5 5.1 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Presenilin PF01080.12 ETO15891.1 - 0.57 8.9 5.0 0.7 8.6 3.4 1.0 1 0 0 1 1 1 0 Presenilin DHHW PF14286.1 ETO15891.1 - 0.82 8.9 5.6 1.1 8.5 3.9 1.1 1 0 0 1 1 1 0 DHHW protein DUF4614 PF15391.1 ETO15891.1 - 1 9.1 12.5 1.4 8.6 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Ebola_NP PF05505.7 ETO15891.1 - 2.9 5.8 10.5 3.6 5.5 7.3 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein CDC45 PF02724.9 ETO15891.1 - 3.7 5.4 12.7 4.7 5.1 8.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 ETO15891.1 - 7.1 4.1 11.5 8 4.0 8.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ketoacyl-synt PF00109.21 ETO15894.1 - 2.6e-28 99.2 0.7 4.1e-28 98.5 0.5 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 ETO15894.1 - 4.3e-23 81.4 0.2 4.3e-23 81.4 0.1 2.4 2 1 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 ETO15894.1 - 0.0034 16.3 0.3 0.0057 15.6 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Hydrolase_3 PF08282.7 ETO15895.1 - 0.0011 18.6 0.6 0.0017 17.9 0.4 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 ETO15896.1 - 7.6e-09 36.2 0.1 9.6e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETO15896.1 - 8.1e-09 35.3 0.4 3.3e-07 30.1 0.0 3.1 3 0 0 3 3 3 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 ETO15896.1 - 2.6e-05 24.4 0.0 3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HlyD PF00529.15 ETO15896.1 - 0.036 13.3 0.9 0.059 12.6 0.6 1.3 1 0 0 1 1 1 0 HlyD family secretion protein DUF4473 PF14747.1 ETO15896.1 - 0.067 13.4 0.1 0.067 13.4 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) Kinase-PPPase PF03618.9 ETO15896.1 - 0.09 12.2 1.2 0.14 11.6 0.7 1.4 1 1 0 1 1 1 0 Kinase/pyrophosphorylase NDUF_B6 PF09782.4 ETO15896.1 - 0.14 11.9 0.8 0.41 10.4 0.1 1.9 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit Taxilin PF09728.4 ETO15896.1 - 0.21 10.6 7.0 2.5 7.1 0.1 2.1 2 0 0 2 2 2 0 Myosin-like coiled-coil protein Tim54 PF11711.3 ETO15897.1 - 0.044 12.3 4.1 0.055 12.0 2.9 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Zip PF02535.17 ETO15897.1 - 0.13 11.2 2.3 0.17 10.8 1.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter AAA_23 PF13476.1 ETO15897.1 - 0.28 11.5 9.7 0.46 10.7 6.8 1.4 1 0 0 1 1 1 0 AAA domain Cellulose_synt PF03552.9 ETO15897.1 - 0.32 9.2 1.7 0.33 9.2 1.1 1.2 1 0 0 1 1 1 0 Cellulose synthase PBP_sp32 PF07222.7 ETO15897.1 - 2.9 6.9 14.2 3.7 6.6 9.8 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 RRM_3 PF08777.6 ETO15897.1 - 5.6 6.8 9.0 0.7 9.7 2.6 2.1 1 1 1 2 2 2 0 RNA binding motif Mucin PF01456.12 ETO15898.1 - 0.0024 17.6 12.6 0.0024 17.6 8.7 3.5 3 1 0 3 3 3 3 Mucin-like glycoprotein PPR_2 PF13041.1 ETO15899.1 - 1.7e-05 24.6 2.4 3.4 7.7 0.0 4.9 4 1 1 5 5 5 4 PPR repeat family PPR PF01535.15 ETO15899.1 - 0.0072 16.2 2.3 0.14 12.1 0.0 3.7 4 0 0 4 4 4 1 PPR repeat DAGAT PF03982.8 ETO15901.1 - 0.069 11.8 1.1 0.21 10.2 0.1 1.9 2 0 0 2 2 2 0 Diacylglycerol acyltransferase DUF898 PF05987.8 ETO15902.1 - 0.58 8.9 6.1 1 8.1 4.2 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) TPPK_C PF12555.3 ETO15902.1 - 3.5 7.4 8.2 0.38 10.5 0.8 2.5 2 1 0 2 2 2 0 Thiamine pyrophosphokinase C terminal MBOAT PF03062.14 ETO15903.1 - 5.5e-26 91.4 14.4 8.8e-26 90.7 10.0 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Ebola_NP PF05505.7 ETO15904.1 - 0.015 13.3 5.9 0.019 13.0 4.1 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein LicD PF04991.8 ETO15904.1 - 0.03 14.4 6.3 0.04 14.0 4.4 1.3 1 1 0 1 1 1 0 LicD family GAGA_bind PF06217.7 ETO15904.1 - 0.034 14.1 4.5 0.041 13.8 3.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Sec62 PF03839.11 ETO15904.1 - 1.1 8.6 10.6 1.5 8.2 7.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF3391 PF11871.3 ETO15905.1 - 0.0064 16.6 0.3 0.011 15.8 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3391) Mem_trans PF03547.13 ETO15906.1 - 0.17 10.1 1.0 0.18 10.0 0.7 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF912 PF06024.7 ETO15907.1 - 0.03 14.3 3.4 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ETRAMP PF09716.5 ETO15908.1 - 0.0023 17.8 0.3 0.0023 17.8 0.2 4.0 4 1 0 4 4 4 1 Malarial early transcribed membrane protein (ETRAMP) SPX PF03105.14 ETO15908.1 - 0.012 15.3 1.3 0.012 15.3 0.9 2.5 2 1 0 2 2 2 0 SPX domain IncA PF04156.9 ETO15908.1 - 0.013 15.0 14.7 0.073 12.6 0.4 3.6 2 1 1 3 3 3 0 IncA protein PAH PF02671.16 ETO15908.1 - 0.91 9.1 6.0 6.6 6.4 0.2 4.0 4 0 0 4 4 4 0 Paired amphipathic helix repeat Reo_sigmaC PF04582.7 ETO15908.1 - 2.1 7.4 5.3 0.57 9.3 1.4 1.6 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF843 PF05814.6 ETO15908.1 - 2.2 8.1 11.2 4.9 7.0 0.8 4.1 3 0 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) DUF148 PF02520.12 ETO15908.1 - 4.8 7.0 16.9 0.09 12.5 4.1 3.5 3 2 0 3 3 3 0 Domain of unknown function DUF148 Glutaredoxin2_C PF04399.8 ETO15908.1 - 7.9 6.0 9.7 2.6 7.6 0.9 3.5 2 1 2 4 4 4 0 Glutaredoxin 2, C terminal domain ABC_tran PF00005.22 ETO15909.1 - 0.00048 20.4 0.0 0.00048 20.4 0.0 3.8 3 1 0 3 3 3 1 ABC transporter AAA_29 PF13555.1 ETO15909.1 - 0.0032 16.9 0.1 0.0073 15.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Miro PF08477.8 ETO15909.1 - 0.0079 16.6 6.1 0.052 14.0 0.0 4.6 3 1 1 4 4 4 1 Miro-like protein AAA_16 PF13191.1 ETO15909.1 - 0.029 14.3 0.4 0.46 10.4 0.0 3.1 2 1 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.18 ETO15909.1 - 0.032 14.1 0.0 0.032 14.1 0.0 4.5 5 1 1 6 6 6 0 50S ribosome-binding GTPase AAA_22 PF13401.1 ETO15909.1 - 0.46 10.6 0.0 0.46 10.6 0.0 5.1 5 0 0 5 5 5 0 AAA domain Daxx PF03344.10 ETO15910.1 - 0.044 12.2 18.6 0.062 11.7 12.9 1.3 1 0 0 1 1 1 0 Daxx Family Ribosomal_60s PF00428.14 ETO15910.1 - 0.053 13.9 8.9 0.092 13.1 6.2 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Sigma70_ner PF04546.8 ETO15910.1 - 0.055 13.0 8.7 0.074 12.6 6.0 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.5 ETO15910.1 - 0.056 13.6 8.0 0.1 12.8 5.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TFIIF_alpha PF05793.7 ETO15910.1 - 0.057 11.7 19.8 0.066 11.5 13.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 ETO15910.1 - 0.25 9.2 14.9 0.28 9.0 10.3 1.1 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.13 ETO15910.1 - 0.37 9.9 16.8 0.47 9.5 11.6 1.3 1 1 0 1 1 1 0 Myc amino-terminal region Nucleoplasmin PF03066.10 ETO15910.1 - 0.72 9.3 14.2 0.77 9.2 8.7 1.9 2 0 0 2 2 2 0 Nucleoplasmin DUF2422 PF10337.4 ETO15910.1 - 0.78 8.4 2.6 1.1 8.0 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) TRAP_alpha PF03896.11 ETO15910.1 - 1 8.3 6.8 1.5 7.7 4.7 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Mak16 PF04874.9 ETO15910.1 - 1.2 9.2 17.8 2.5 8.2 12.4 1.5 1 0 0 1 1 1 0 Mak16 protein C-terminal region Ycf1 PF05758.7 ETO15910.1 - 1.5 6.4 10.0 1.6 6.3 6.9 1.1 1 0 0 1 1 1 0 Ycf1 CDC45 PF02724.9 ETO15910.1 - 2.5 6.0 12.5 2.6 5.9 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.10 ETO15910.1 - 2.7 7.1 14.4 3.2 6.9 10.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Vfa1 PF08432.5 ETO15910.1 - 3.2 7.7 17.0 5.6 6.9 11.7 1.4 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CobT PF06213.7 ETO15910.1 - 3.5 6.6 15.3 4.7 6.2 10.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BSP_II PF05432.6 ETO15910.1 - 6.4 5.9 23.7 2.7 7.2 14.7 1.6 1 1 0 1 1 1 0 Bone sialoprotein II (BSP-II) GlcNAc PF11397.3 ETO15911.1 - 1e-51 176.1 0.0 1.2e-51 175.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) Kelch_6 PF13964.1 ETO15912.1 - 0.00019 21.4 0.9 0.00019 21.4 0.6 2.7 2 1 1 3 3 3 1 Kelch motif Kelch_1 PF01344.20 ETO15912.1 - 0.0085 15.6 4.6 0.011 15.2 1.0 2.4 2 0 0 2 2 2 1 Kelch motif DUF4448 PF14610.1 ETO15912.1 - 0.011 15.2 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Kelch_5 PF13854.1 ETO15912.1 - 0.017 15.0 1.7 0.017 15.0 1.2 2.4 2 0 0 2 2 2 0 Kelch motif Orthoreo_P10 PF07204.6 ETO15912.1 - 0.072 12.8 0.0 3 7.6 0.0 2.4 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 Kelch_3 PF13415.1 ETO15912.1 - 0.092 12.9 0.7 0.092 12.9 0.5 2.6 3 1 0 3 3 3 0 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO15912.1 - 0.14 11.9 1.6 0.16 11.7 0.2 1.8 2 0 0 2 2 2 0 Galactose oxidase, central domain DUF2981 PF11200.3 ETO15912.1 - 0.9 8.5 3.5 1.3 7.9 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) AF-4 PF05110.8 ETO15912.1 - 4.7 4.9 10.8 6.3 4.5 7.5 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein EF-hand_5 PF13202.1 ETO15913.1 - 0.0013 17.9 0.0 0.0033 16.6 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.27 ETO15913.1 - 0.075 12.3 0.1 0.24 10.7 0.0 1.9 1 0 0 1 1 1 0 EF hand Caveolin PF01146.12 ETO15913.1 - 2.3 7.8 7.2 4.3 6.9 5.0 1.4 1 0 0 1 1 1 0 Caveolin DUF788 PF05620.6 ETO15914.1 - 0.03 14.1 0.3 0.03 14.1 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF788) Seadorna_VP6 PF07407.6 ETO15914.1 - 0.088 11.5 0.6 0.11 11.2 0.4 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein G-alpha PF00503.15 ETO15917.1 - 5.1e-94 315.1 8.9 6e-94 314.9 6.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO15917.1 - 1.6e-13 50.3 0.7 4.5e-10 39.0 0.3 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETO15917.1 - 0.00093 18.3 4.6 0.028 13.5 0.4 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 ETO15917.1 - 0.0023 18.4 0.1 3.5 8.1 0.0 3.0 2 2 1 3 3 3 2 Miro-like protein AAA_22 PF13401.1 ETO15917.1 - 0.0074 16.4 0.1 0.032 14.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 ETO15917.1 - 0.012 15.2 2.0 1.3 8.6 0.1 2.8 2 1 0 2 2 2 0 Archaeal ATPase AAA_29 PF13555.1 ETO15917.1 - 0.057 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TPR_11 PF13414.1 ETO15917.1 - 0.1 12.2 0.4 0.57 9.8 0.3 2.1 1 1 0 1 1 1 0 TPR repeat MMR_HSR1 PF01926.18 ETO15917.1 - 0.1 12.5 0.0 2.6 8.0 0.0 2.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 ETO15917.1 - 0.1 12.0 0.0 0.36 10.2 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family TPR_7 PF13176.1 ETO15917.1 - 0.11 12.4 0.0 21 5.2 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Acyl-CoA_ox_N PF14749.1 ETO15917.1 - 1.3 9.3 5.8 1.8 8.8 0.3 2.8 3 0 0 3 3 3 0 Acyl-coenzyme A oxidase N-terminal DUF3586 PF12131.3 ETO15918.1 - 0.0018 18.2 8.8 0.033 14.2 1.9 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF3586) Pox_Ag35 PF03286.9 ETO15919.1 - 0.0027 17.2 16.4 0.0027 17.2 11.4 3.1 3 0 0 3 3 3 1 Pox virus Ag35 surface protein Hexokinase_2 PF03727.11 ETO15920.1 - 0.043 13.0 0.1 0.058 12.5 0.1 1.3 1 0 0 1 1 1 0 Hexokinase Methyltransf_20 PF12147.3 ETO15920.1 - 0.06 12.2 0.0 0.08 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Cse1 PF08506.5 ETO15921.1 - 6.4e-16 57.8 1.8 2.4e-15 55.9 1.2 1.9 1 1 0 1 1 1 1 Cse1 zf-C2H2 PF00096.21 ETO15922.1 - 0.0011 19.2 2.5 0.0011 19.2 1.7 2.7 2 1 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETO15922.1 - 0.003 17.7 2.3 0.003 17.7 1.6 2.7 2 1 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETO15922.1 - 0.79 10.1 13.5 2.4 8.6 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger double domain DSPc PF00782.15 ETO15923.1 - 9.4e-31 106.1 0.4 1.3e-30 105.7 0.3 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 ETO15923.1 - 2.1e-06 26.9 0.2 2.5e-06 26.6 0.2 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase PF00102.22 ETO15923.1 - 2.8e-06 26.8 0.2 3.3e-06 26.6 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 ETO15923.1 - 0.0011 19.0 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 ETO15923.1 - 0.081 13.1 0.0 0.099 12.8 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF4116 PF13475.1 ETO15923.1 - 0.26 10.7 1.5 0.8 9.2 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) zf-UBR PF02207.15 ETO15925.1 - 5.4e-21 74.0 13.9 8.6e-21 73.4 9.6 1.3 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Ammonium_transp PF00909.16 ETO15926.1 - 5e-17 61.4 0.2 5.1e-17 61.4 0.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family SET PF00856.23 ETO15927.1 - 2.1e-12 47.6 0.0 1.4e-09 38.4 0.0 2.2 1 1 0 1 1 1 1 SET domain DUF3657 PF12394.3 ETO15928.1 - 1.8e-09 37.4 1.2 1.7e-08 34.3 0.4 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3657) CBM_21 PF03370.8 ETO15928.1 - 0.011 15.6 0.2 0.023 14.6 0.1 1.5 1 0 0 1 1 1 0 Putative phosphatase regulatory subunit Plasmodium_Vir PF05795.6 ETO15929.1 - 0.0033 16.6 3.2 0.0037 16.5 2.2 1.1 1 0 0 1 1 1 1 Plasmodium vivax Vir protein Neur_chan_memb PF02932.11 ETO15929.1 - 2.3 8.0 15.4 2.6 7.8 10.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ABC2_membrane_2 PF12679.2 ETO15929.1 - 2.8 6.7 5.2 3.2 6.5 3.6 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Ycf1 PF05758.7 ETO15929.1 - 2.9 5.4 19.7 3.1 5.4 13.6 1.0 1 0 0 1 1 1 0 Ycf1 DUF2140 PF09911.4 ETO15929.1 - 3 6.9 11.5 3.7 6.6 8.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Otopetrin PF03189.8 ETO15929.1 - 4 6.3 7.6 3.8 6.4 5.3 1.2 1 0 0 1 1 1 0 Otopetrin DUF3595 PF12166.3 ETO15929.1 - 6.3 5.4 15.8 6.5 5.4 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) HGTP_anticodon2 PF12745.2 ETO15929.1 - 6.6 5.7 18.6 6.8 5.7 12.9 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Glyco_transf_15 PF01793.11 ETO15929.1 - 7.9 5.3 16.7 8 5.3 11.6 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Tim54 PF11711.3 ETO15929.1 - 9.2 4.7 13.1 9.4 4.7 9.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Rubis-subs-bind PF09273.6 ETO15932.1 - 0.027 14.3 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 Rubisco LSMT substrate-binding DUF4472 PF14739.1 ETO15933.1 - 7.2e-09 36.0 18.2 7.2e-09 36.0 12.6 7.9 4 2 1 6 6 6 2 Domain of unknown function (DUF4472) Mnd1 PF03962.10 ETO15933.1 - 0.0023 17.5 8.8 0.0023 17.5 6.1 7.2 1 1 6 7 7 7 1 Mnd1 family RAP1 PF07218.6 ETO15934.1 - 0.00029 19.0 12.1 0.00048 18.3 8.4 1.3 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) SPOC PF07744.8 ETO15934.1 - 0.0037 17.7 0.0 0.019 15.4 0.0 2.2 2 0 0 2 2 2 1 SPOC domain Pex14_N PF04695.8 ETO15934.1 - 0.009 16.0 1.7 0.009 16.0 1.2 3.8 4 0 0 4 4 4 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Corona_nucleoca PF00937.13 ETO15934.1 - 0.034 13.0 10.6 0.12 11.3 7.3 1.9 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein WD40 PF00400.27 ETO15935.1 - 2.1e-50 166.9 19.1 4.9e-10 38.8 0.4 7.1 7 1 1 8 8 8 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO15935.1 - 1.2e-07 30.2 0.7 0.017 13.3 0.0 3.5 2 1 1 3 3 3 2 Nucleoporin Nup120/160 PQQ_3 PF13570.1 ETO15935.1 - 0.013 15.7 0.7 19 5.7 0.0 4.1 4 1 0 4 4 4 0 PQQ-like domain TetM_leader PF08076.6 ETO15935.1 - 8.5 6.0 10.6 11 5.6 0.1 4.0 4 0 0 4 4 4 0 Tetracycline resistance determinant leader peptide MCPsignal PF00015.16 ETO15936.1 - 0.0015 18.0 0.1 0.0015 18.0 0.1 2.1 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain COG2 PF06148.6 ETO15936.1 - 0.0017 18.1 1.3 0.0017 18.1 0.9 2.9 2 1 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin PF00804.20 ETO15936.1 - 0.0061 16.6 0.8 0.0061 16.6 0.5 2.9 2 1 0 2 2 1 1 Syntaxin DUF948 PF06103.6 ETO15936.1 - 0.012 15.3 3.8 0.018 14.8 0.1 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) UPF0184 PF03670.8 ETO15936.1 - 0.017 15.2 1.2 0.017 15.2 0.8 2.6 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0184) Reo_sigmaC PF04582.7 ETO15936.1 - 0.026 13.7 0.2 0.042 13.0 0.1 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Glyco_hydro_1 PF00232.13 ETO15936.1 - 0.052 11.7 2.7 0.088 10.9 1.8 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 Seryl_tRNA_N PF02403.17 ETO15936.1 - 0.25 11.3 0.0 0.25 11.3 0.0 2.8 2 1 0 3 3 2 0 Seryl-tRNA synthetase N-terminal domain HNOB PF07700.10 ETO15936.1 - 0.28 10.7 4.6 0.19 11.2 1.8 1.7 2 0 0 2 2 2 0 Heme NO binding Mitofilin PF09731.4 ETO15936.1 - 0.4 9.2 15.9 1.1 7.8 11.0 1.6 1 1 0 1 1 1 0 Mitochondrial inner membrane protein Baculo_PEP_C PF04513.7 ETO15936.1 - 0.47 10.2 2.5 0.7 9.7 0.1 2.2 2 2 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PEX11 PF05648.9 ETO15936.1 - 0.64 9.2 8.5 0.52 9.5 2.9 2.1 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) DASH_Dad1 PF08649.5 ETO15936.1 - 0.79 9.4 9.5 16 5.2 3.0 3.5 2 2 1 3 3 3 0 DASH complex subunit Dad1 DUF3347 PF11827.3 ETO15936.1 - 0.84 9.6 14.6 0.23 11.4 5.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) Secretin_N_2 PF07655.8 ETO15936.1 - 5.3 7.4 10.0 3.6 8.0 0.3 2.8 3 0 0 3 3 3 0 Secretin N-terminal domain DUF1664 PF07889.7 ETO15936.1 - 6.2 6.6 9.9 0.31 10.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Spore_II_R PF09551.5 ETO15936.1 - 9.3 6.2 10.6 6.2 6.8 3.0 2.3 2 0 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) I_LWEQ PF01608.12 ETO15937.1 - 0.003 17.5 0.0 0.0055 16.6 0.0 1.4 1 0 0 1 1 1 1 I/LWEQ domain Proteasome PF00227.21 ETO15938.1 - 1.9e-05 24.0 0.7 2.6e-05 23.5 0.1 1.5 2 0 0 2 2 2 1 Proteasome subunit FACT-Spt16_Nlob PF14826.1 ETO15938.1 - 0.13 11.7 3.7 0.16 11.4 2.6 1.1 1 0 0 1 1 1 0 FACT complex subunit SPT16 N-terminal lobe domain Rio2_N PF09202.6 ETO15938.1 - 0.14 12.2 0.3 0.18 11.8 0.2 1.2 1 0 0 1 1 1 0 Rio2, N-terminal GTP_CH_N PF12471.3 ETO15939.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.5 1 1 0 1 1 1 0 GTP cyclohydrolase N terminal Sialidase PF02973.11 ETO15940.1 - 0.053 12.5 0.0 0.097 11.6 0.0 1.5 1 1 0 1 1 1 0 Sialidase, N-terminal domain AAA PF00004.24 ETO15941.1 - 7.2e-09 35.9 0.0 1.6e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF912 PF06024.7 ETO15942.1 - 0.39 10.7 5.1 0.55 10.3 1.5 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ATP-synt_ab PF00006.20 ETO15943.1 - 0.0095 15.4 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Methylase_S PF01420.14 ETO15943.1 - 0.065 13.2 2.3 3.1 7.7 0.2 2.2 2 0 0 2 2 2 0 Type I restriction modification DNA specificity domain IncA PF04156.9 ETO15945.1 - 0.0072 15.9 4.9 0.0072 15.9 3.4 2.2 3 0 0 3 3 3 1 IncA protein Pex14_N PF04695.8 ETO15945.1 - 0.013 15.5 6.2 0.49 10.4 2.7 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3357 PF11837.3 ETO15945.1 - 0.095 12.5 0.2 24 4.8 0.0 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) Shisa PF13908.1 ETO15945.1 - 0.2 11.8 24.9 0.069 13.3 7.5 3.2 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 ETO15945.1 - 0.48 10.8 0.0 0.48 10.8 0.0 4.4 5 0 0 5 5 5 0 Ephrin type-A receptor 2 transmembrane domain Gag_spuma PF03276.9 ETO15945.1 - 2.4 6.3 9.6 4 5.6 6.6 1.3 1 0 0 1 1 1 0 Spumavirus gag protein PHD PF00628.24 ETO15946.1 - 0.0016 18.0 3.1 0.0059 16.2 2.1 2.0 1 0 0 1 1 1 1 PHD-finger FYVE_2 PF02318.11 ETO15946.1 - 0.0028 17.5 1.9 0.0085 15.9 1.3 1.8 1 0 0 1 1 1 1 FYVE-type zinc finger MIP-T3 PF10243.4 ETO15946.1 - 0.078 11.4 58.2 0.14 10.6 40.4 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Utp14 PF04615.8 ETO15946.1 - 0.48 8.5 59.1 0.68 8.0 41.0 1.1 1 0 0 1 1 1 0 Utp14 protein Macoilin PF09726.4 ETO15946.1 - 0.5 8.5 51.1 0.72 8.0 35.5 1.2 1 0 0 1 1 1 0 Transmembrane protein Peptidase_M41 PF01434.13 ETO15947.1 - 1e-65 221.2 0.0 1e-65 221.2 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 ETO15947.1 - 3.9e-42 143.5 0.0 7.4e-42 142.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 ETO15947.1 - 5e-05 24.1 0.1 0.00042 21.1 0.0 2.4 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.1 ETO15947.1 - 0.00012 22.2 0.0 0.0048 17.0 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 ETO15947.1 - 0.00035 20.2 0.0 0.0013 18.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 ETO15947.1 - 0.001 19.1 0.1 0.0083 16.1 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 ETO15947.1 - 0.0019 17.8 0.3 0.011 15.5 0.2 2.1 2 0 0 2 2 2 1 Part of AAA domain RuvB_N PF05496.7 ETO15947.1 - 0.0046 16.0 0.0 0.04 12.9 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 ETO15947.1 - 0.0058 16.5 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETO15947.1 - 0.0077 16.1 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 ETO15947.1 - 0.0085 15.5 0.1 0.02 14.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 ETO15947.1 - 0.011 15.1 0.7 0.16 11.3 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.1 ETO15947.1 - 0.03 14.6 0.6 0.26 11.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 ETO15947.1 - 0.042 12.9 0.2 0.11 11.7 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PrsW-protease PF13367.1 ETO15948.1 - 2.6e-13 49.6 8.6 3.7e-13 49.0 6.0 1.2 1 0 0 1 1 1 1 Protease prsW family DUF2324 PF10086.4 ETO15948.1 - 0.013 14.7 0.8 0.034 13.3 0.0 1.8 1 1 1 2 2 2 0 Putative membrane peptidase family (DUF2324) Cep57_MT_bd PF06657.8 ETO15949.1 - 0.011 15.6 6.4 0.081 12.8 0.2 2.6 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Rota_NSP3 PF01665.11 ETO15949.1 - 0.049 12.5 0.6 0.072 12.0 0.4 1.3 1 1 0 1 1 1 0 Rotavirus non-structural protein NSP3 Mito_fiss_reg PF05308.6 ETO15949.1 - 0.08 12.3 2.5 0.11 11.8 1.8 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Rootletin PF15035.1 ETO15949.1 - 0.13 12.2 5.3 0.18 11.7 3.7 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Mnd1 PF03962.10 ETO15949.1 - 0.15 11.7 3.5 0.2 11.3 2.4 1.3 1 0 0 1 1 1 0 Mnd1 family Seryl_tRNA_N PF02403.17 ETO15949.1 - 0.28 11.1 5.5 0.3 11.1 2.7 1.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CENP-F_leu_zip PF10473.4 ETO15949.1 - 0.52 10.1 10.7 1.4 8.7 1.2 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TSC22 PF01166.13 ETO15949.1 - 0.75 9.8 3.9 0.7 9.8 0.1 2.5 2 2 1 3 3 3 0 TSC-22/dip/bun family FliJ PF02050.11 ETO15949.1 - 3.8 7.5 9.5 0.29 11.1 3.3 1.6 2 0 0 2 2 2 0 Flagellar FliJ protein FKBP_C PF00254.23 ETO15950.1 - 5.4e-12 45.5 0.0 1.1e-11 44.5 0.0 1.7 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase JAB PF01398.16 ETO15951.1 - 2.1e-18 66.1 0.7 7.3e-18 64.3 0.1 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 ETO15951.1 - 3.3e-07 30.2 2.8 6.5e-07 29.3 1.9 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.1 ETO15951.1 - 1.1e-05 24.8 0.0 2.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Glypican PF01153.14 ETO15951.1 - 0.12 10.9 2.9 0.16 10.5 2.0 1.1 1 0 0 1 1 1 0 Glypican DDHD PF02862.12 ETO15951.1 - 0.48 10.1 2.9 0.26 11.0 0.4 1.8 2 0 0 2 2 2 0 DDHD domain GCHY-1 PF02649.9 ETO15952.1 - 0.0098 15.1 0.7 0.016 14.4 0.3 1.4 1 1 0 1 1 1 1 Type I GTP cyclohydrolase folE2 BLVR PF06375.6 ETO15952.1 - 0.018 14.8 19.2 0.018 14.9 4.6 2.1 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) MCR_D PF02505.9 ETO15952.1 - 0.032 13.7 0.6 0.061 12.8 0.4 1.5 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein D DUF3825 PF12873.2 ETO15952.1 - 0.064 12.3 1.7 0.069 12.2 1.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3825) Sec16 PF12932.2 ETO15952.1 - 0.57 10.1 3.5 0.75 9.7 1.4 1.9 1 1 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region DUF4351 PF14261.1 ETO15952.1 - 1.1 9.1 4.5 0.44 10.4 1.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) RNA_pol_3_Rpc31 PF11705.3 ETO15952.1 - 1.4 8.7 19.1 0.013 15.4 4.4 2.0 1 1 1 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Mit_KHE1 PF10173.4 ETO15952.1 - 2.2 8.0 8.7 0.2 11.5 2.6 1.7 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related DUF4647 PF15504.1 ETO15952.1 - 4.2 6.1 16.8 4.6 5.9 0.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4647) WD40 PF00400.27 ETO15953.1 - 1.9e-41 138.5 2.2 7.5e-13 47.8 0.2 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO15953.1 - 2.1e-05 22.8 0.5 0.024 12.8 0.0 2.7 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO15953.1 - 0.00029 19.7 0.5 1.7 7.2 0.0 3.1 2 1 1 3 3 3 3 Nup133 N terminal like PD40 PF07676.7 ETO15953.1 - 0.0045 16.6 0.6 2.8 7.6 0.0 2.8 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO15953.1 - 0.0056 15.0 0.0 0.0082 14.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain rpo30_N PF12410.3 ETO15953.1 - 0.066 12.8 2.9 5.1 6.7 0.0 3.0 1 1 2 3 3 3 0 Poxvirus DNA dependent RNA polymerase 30kDa subunit WD40 PF00400.27 ETO15954.1 - 2.7e-86 280.6 23.0 2.1e-13 49.5 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO15954.1 - 4.6e-11 41.5 6.9 0.0031 15.7 0.1 5.0 1 1 4 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO15954.1 - 1.3e-10 41.2 1.5 1.6e-05 24.6 0.0 3.5 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO15954.1 - 5.7e-06 24.8 0.5 0.12 10.6 0.0 3.0 2 1 2 4 4 4 3 Cytochrome D1 heme domain Str_synth PF03088.11 ETO15954.1 - 8.9e-05 22.4 1.0 19 5.3 0.0 5.0 4 1 1 5 5 5 0 Strictosidine synthase PQQ_2 PF13360.1 ETO15954.1 - 0.00018 21.0 0.9 0.055 12.9 0.1 2.7 1 1 1 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 ETO15954.1 - 0.00066 18.5 10.5 0.015 14.0 0.3 3.8 2 1 0 3 3 3 2 Nup133 N terminal like PA14 PF07691.7 ETO15954.1 - 0.019 14.6 0.1 0.12 11.9 0.0 2.3 2 0 0 2 2 2 0 PA14 domain DUF1652 PF07865.6 ETO15954.1 - 0.019 14.5 0.1 7 6.3 0.0 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF1652) RicinB_lectin_2 PF14200.1 ETO15954.1 - 0.022 15.1 0.6 2.9 8.3 0.0 3.7 1 1 3 4 4 4 0 Ricin-type beta-trefoil lectin domain-like Ribosomal_L28 PF00830.14 ETO15954.1 - 0.027 14.2 0.1 11 5.9 0.0 4.0 3 1 0 3 3 3 0 Ribosomal L28 family Resistin PF06954.6 ETO15954.1 - 0.053 13.8 5.7 32 4.8 0.0 4.8 2 2 3 6 6 6 0 Resistin PD40 PF07676.7 ETO15954.1 - 0.92 9.2 19.1 2.7 7.7 0.2 6.0 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 ETO15954.1 - 1.4 8.3 3.6 50 3.3 0.0 3.7 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature PHB_acc PF05233.8 ETO15955.1 - 0.0019 17.8 2.7 0.0036 17.0 0.2 2.5 2 0 0 2 2 2 1 PHB accumulation regulatory domain DUF3456 PF11938.3 ETO15955.1 - 0.0024 17.8 3.8 0.0024 17.8 2.7 2.5 1 1 2 3 3 3 1 TLR4 regulator and MIR-interacting MSAP CENP-T PF15511.1 ETO15956.1 - 0.0021 17.3 28.5 0.0025 17.1 19.8 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Daxx PF03344.10 ETO15956.1 - 0.05 12.0 43.6 0.059 11.8 30.2 1.1 1 0 0 1 1 1 0 Daxx Family YL1 PF05764.8 ETO15956.1 - 0.085 12.4 44.9 0.14 11.7 31.1 1.4 1 0 0 1 1 1 0 YL1 nuclear protein DUF572 PF04502.8 ETO15956.1 - 0.76 8.9 20.1 1.1 8.4 13.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Herpes_DNAp_acc PF04929.7 ETO15956.1 - 1.4 7.8 9.7 1.8 7.4 6.7 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor UPF0233 PF06781.7 ETO15957.1 - 0.56 9.8 0.0 0.56 9.8 0.0 2.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) DUF4179 PF13786.1 ETO15958.1 - 0.034 14.3 0.3 0.034 14.3 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) ETRAMP PF09716.5 ETO15958.1 - 0.76 9.7 3.9 0.48 10.4 0.1 2.3 2 1 1 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Annexin PF00191.15 ETO15959.1 - 0.00019 21.2 0.0 0.011 15.5 0.0 2.3 2 0 0 2 2 2 2 Annexin Annexin PF00191.15 ETO15960.1 - 1e-24 86.2 5.4 8.6e-11 41.5 0.1 5.1 4 1 0 4 4 4 4 Annexin DUF4172 PF13776.1 ETO15960.1 - 0.046 13.8 0.4 0.33 11.0 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4172) NYD-SP28 PF14772.1 ETO15960.1 - 1.4 9.0 6.3 6.9 6.8 0.1 3.3 3 0 0 3 3 3 0 Sperm tail Annexin PF00191.15 ETO15961.1 - 0.00021 21.1 0.0 0.00042 20.1 0.0 1.5 1 0 0 1 1 1 1 Annexin DUF3292 PF11696.3 ETO15961.1 - 0.024 12.5 0.1 0.027 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) ATP-synt_E PF05680.7 ETO15962.1 - 0.087 12.7 3.4 0.13 12.2 2.3 1.3 1 0 0 1 1 1 0 ATP synthase E chain Protocadherin PF08374.6 ETO15962.1 - 0.37 10.4 2.5 0.42 10.2 1.7 1.1 1 0 0 1 1 1 0 Protocadherin DUF4519 PF15012.1 ETO15962.1 - 1.8 8.5 9.6 3.4 7.6 6.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) MotCF PF09158.5 ETO15963.1 - 0.0053 16.4 0.5 0.17 11.5 0.0 2.9 1 1 2 3 3 3 1 Bacteriophage T4 MotA, C-terminal Synaptobrevin PF00957.16 ETO15963.1 - 0.058 13.0 0.9 0.14 11.7 0.6 1.6 1 0 0 1 1 1 0 Synaptobrevin CARM1 PF11531.3 ETO15965.1 - 0.0062 16.2 0.3 0.018 14.7 0.2 1.8 1 0 0 1 1 1 1 Coactivator-associated arginine methyltransferase 1 N terminal UBA PF00627.26 ETO15965.1 - 0.027 14.2 0.1 11 5.9 0.0 2.5 2 0 0 2 2 2 0 UBA/TS-N domain DUF4600 PF15372.1 ETO15967.1 - 0.032 14.4 6.2 0.049 13.8 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) TBD PF12845.2 ETO15967.1 - 0.049 13.1 0.6 0.1 12.1 0.4 1.5 1 0 0 1 1 1 0 TBD domain TAF4 PF05236.9 ETO15967.1 - 0.12 11.6 5.2 0.15 11.3 3.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family zf-DHHC PF01529.15 ETO15967.1 - 0.14 11.5 0.3 0.14 11.5 0.2 2.1 2 1 0 2 2 2 0 DHHC palmitoyltransferase DUF2718 PF10918.3 ETO15967.1 - 0.14 12.2 2.6 0.3 11.1 1.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2718) Pepsin-I3 PF06394.8 ETO15967.1 - 0.18 11.4 1.1 0.46 10.1 0.8 1.7 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain WD40 PF00400.27 ETO15968.1 - 9.4e-119 383.5 27.8 3e-13 49.0 0.2 14.5 13 1 1 14 14 14 14 WD domain, G-beta repeat NACHT PF05729.7 ETO15968.1 - 3.7e-09 36.4 0.0 7.6e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Cytochrom_D1 PF02239.11 ETO15968.1 - 6.6e-07 27.9 4.1 0.24 9.6 0.0 5.4 3 1 3 6 6 6 3 Cytochrome D1 heme domain Pentapeptide PF00805.17 ETO15968.1 - 6.6e-07 28.4 0.4 1.2e-06 27.6 0.3 1.4 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) DUF1258 PF06869.7 ETO15968.1 - 1.8e-06 27.2 4.9 0.35 9.9 0.0 6.0 6 1 2 8 8 8 2 Protein of unknown function (DUF1258) Pentapeptide_4 PF13599.1 ETO15968.1 - 1.8e-06 27.6 0.6 3.6e-05 23.4 0.1 2.7 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 ETO15968.1 - 7.6e-06 25.7 0.1 2e-05 24.3 0.1 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA_22 PF13401.1 ETO15968.1 - 9.3e-05 22.5 0.0 0.00035 20.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETO15968.1 - 0.0017 18.6 0.2 0.015 15.6 0.0 2.9 2 0 0 2 2 1 1 AAA domain AAA PF00004.24 ETO15968.1 - 0.015 15.5 0.0 0.39 10.9 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETO15968.1 - 0.034 14.1 0.5 0.75 9.7 0.1 3.1 2 1 0 2 2 2 0 AAA ATPase domain ATP_bind_2 PF03668.10 ETO15968.1 - 0.046 12.8 0.0 0.087 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop ATPase protein family PD40 PF07676.7 ETO15968.1 - 0.046 13.3 25.3 7.2 6.3 0.0 8.4 10 0 0 10 10 10 0 WD40-like Beta Propeller Repeat AAA_17 PF13207.1 ETO15968.1 - 0.05 14.4 0.0 0.35 11.7 0.0 2.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 ETO15968.1 - 0.12 12.6 0.0 0.12 12.6 0.0 4.4 4 1 1 5 5 5 0 RNA helicase Arylesterase PF01731.15 ETO15969.1 - 1.9 8.5 5.7 46 4.0 0.1 3.8 4 0 0 4 4 4 0 Arylesterase Vps51 PF08700.6 ETO15970.1 - 1.7e-08 34.1 2.6 3.8e-08 33.0 1.7 1.6 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 ETO15970.1 - 9.1e-06 25.5 0.5 1.4e-05 24.9 0.4 1.3 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF4611 PF15387.1 ETO15970.1 - 0.023 14.8 3.3 0.062 13.4 2.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF2450 PF10475.4 ETO15970.1 - 0.024 13.5 1.1 0.036 12.9 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) FlaC_arch PF05377.6 ETO15970.1 - 0.1 12.5 2.2 0.23 11.3 1.6 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) GCIP PF13324.1 ETO15970.1 - 0.11 11.6 6.1 0.25 10.5 4.3 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Macoilin PF09726.4 ETO15970.1 - 0.6 8.3 12.5 0.78 7.9 8.7 1.3 1 0 0 1 1 1 0 Transmembrane protein Fib_alpha PF08702.5 ETO15970.1 - 1.4 9.0 5.8 0.14 12.3 0.5 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF506 PF04720.7 ETO15970.1 - 2.9 7.4 12.5 0.64 9.6 5.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF506) Utp14 PF04615.8 ETO15971.1 - 1 7.4 13.2 1.2 7.2 9.2 1.0 1 0 0 1 1 1 0 Utp14 protein Menin PF05053.8 ETO15971.1 - 1.6 6.8 12.7 1.7 6.7 8.8 1.1 1 0 0 1 1 1 0 Menin eIF_4EBP PF05456.6 ETO15971.1 - 1.7 8.3 8.6 0.73 9.5 3.5 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Oxidored_q3 PF00499.15 ETO15972.1 - 0.56 9.9 5.7 1 9.1 3.9 1.6 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 ETRAMP PF09716.5 ETO15972.1 - 2.9 7.9 11.0 0.51 10.3 3.2 2.3 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Chordopox_G3 PF06129.7 ETO15972.1 - 6.1 7.0 8.9 3.6 7.7 4.7 1.8 2 1 0 2 2 2 0 Chordopoxvirus G3 protein SNF2_N PF00176.18 ETO15973.1 - 4.2e-35 120.9 0.4 5.2e-35 120.6 0.3 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 ETO15973.1 - 3.4e-05 23.7 0.0 7.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 ETO15973.1 - 0.0041 16.6 0.0 0.039 13.4 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.4 ETO15973.1 - 0.0056 15.7 0.0 0.0085 15.1 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Helicase_C PF00271.26 ETO15974.1 - 3.2e-14 52.5 0.0 7.4e-14 51.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Paf1 PF03985.8 ETO15975.1 - 2.1e-07 30.0 19.2 1.8e-05 23.6 13.3 2.7 1 1 0 1 1 1 1 Paf1 DapB_C PF05173.9 ETO15975.1 - 0.18 11.5 3.8 5.3 6.8 0.0 3.0 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, C-terminus EF-hand_1 PF00036.27 ETO15977.1 - 8.4e-34 112.2 19.7 2.3e-09 35.8 0.9 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 ETO15977.1 - 6.1e-30 103.1 12.8 7.1e-16 58.1 1.3 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO15977.1 - 1.2e-27 93.2 14.4 1.2e-09 37.2 0.1 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 ETO15977.1 - 8.1e-27 92.6 18.3 2.4e-14 52.6 1.3 4.0 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 ETO15977.1 - 3.1e-21 73.6 19.0 1.2e-06 27.5 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 ETO15977.1 - 9.5e-12 44.6 0.8 5.2e-06 26.2 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 ETO15977.1 - 9.9e-07 28.4 9.7 0.046 13.4 0.4 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 ETO15977.1 - 7.1e-05 22.8 1.5 0.0084 16.1 0.1 2.2 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF853 PF05872.7 ETO15977.1 - 0.0036 15.7 0.3 0.26 9.5 0.0 2.1 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF853) EFhand_Ca_insen PF08726.5 ETO15977.1 - 0.0052 16.7 3.3 0.037 13.9 0.2 2.5 2 0 0 2 2 2 1 Ca2+ insensitive EF hand Tenui_NCP PF04876.7 ETO15977.1 - 0.012 15.2 0.4 0.67 9.4 0.1 2.2 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein DUF4601 PF15373.1 ETO15977.1 - 0.026 13.3 0.2 0.081 11.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4601) RHH_2 PF03693.9 ETO15977.1 - 0.036 14.2 1.2 0.097 12.8 0.1 2.1 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0156) Caleosin PF05042.8 ETO15977.1 - 0.073 12.6 0.4 3.5 7.1 0.0 3.1 1 1 3 4 4 4 0 Caleosin related protein UPF0154 PF03672.8 ETO15977.1 - 0.14 11.7 2.5 16 5.2 0.0 3.2 3 1 1 4 4 3 0 Uncharacterised protein family (UPF0154) TerB PF05099.8 ETO15977.1 - 0.21 11.3 6.3 5.7 6.6 0.8 3.0 1 1 1 2 2 2 0 Tellurite resistance protein TerB Leucyl-specific PF14795.1 ETO15977.1 - 0.23 11.3 3.4 15 5.4 0.0 3.1 3 0 0 3 3 3 0 Leucine-tRNA synthetase-specific domain Toprim_2 PF13155.1 ETO15977.1 - 0.27 11.5 4.7 1.7 8.9 0.6 2.4 1 1 0 2 2 2 0 Toprim-like LTXXQ PF07813.7 ETO15977.1 - 0.58 10.6 4.3 4.9 7.6 2.1 2.2 1 1 1 2 2 2 0 LTXXQ motif family protein FlgD PF03963.9 ETO15977.1 - 1.2 9.2 8.9 9.5 6.3 4.9 2.7 2 1 0 2 2 2 0 Flagellar hook capping protein - N-terminal region MgtE_N PF03448.12 ETO15977.1 - 5 7.5 6.5 0.6 10.4 0.4 2.4 2 1 1 3 3 3 0 MgtE intracellular N domain ERM PF00769.14 ETO15978.1 - 0.00055 19.5 23.1 0.00055 19.5 16.0 2.4 2 1 1 3 3 3 1 Ezrin/radixin/moesin family End3 PF12761.2 ETO15978.1 - 0.14 11.8 19.8 0.28 10.8 13.4 1.7 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 APG6 PF04111.7 ETO15978.1 - 0.44 9.5 27.4 0.79 8.7 19.0 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 ETO15978.1 - 0.72 9.6 32.5 0.11 12.3 10.2 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LMBR1 PF04791.11 ETO15978.1 - 1.2 7.6 10.2 1.4 7.3 7.0 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF3552 PF12072.3 ETO15978.1 - 2.2 7.4 40.8 0.54 9.4 23.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) zf-DHHC PF01529.15 ETO15978.1 - 2.8 7.2 7.0 6.3 6.1 0.0 2.5 2 1 0 2 2 2 0 DHHC palmitoyltransferase CASP_C PF08172.7 ETO15978.1 - 3.7 6.4 21.3 5.6e+02 -0.7 14.7 3.2 1 1 0 1 1 1 0 CASP C terminal CTDII PF01556.13 ETO15979.1 - 1.5e-19 69.6 0.3 7.3e-17 61.0 0.0 3.1 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ PF00226.26 ETO15979.1 - 9.7e-19 66.8 2.5 4.2e-18 64.8 1.7 2.1 1 1 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 ETO15979.1 - 5.2e-05 23.2 17.2 0.0002 21.3 11.9 2.0 1 1 0 1 1 1 1 DnaJ central domain DUF2633 PF11119.3 ETO15979.1 - 0.015 14.9 1.5 0.015 14.9 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) Cytochrome_CBB3 PF13442.1 ETO15979.1 - 0.016 15.3 0.3 0.016 15.3 0.2 3.0 1 1 2 3 3 3 0 Cytochrome C oxidase, cbb3-type, subunit III zf-CCHC_4 PF14392.1 ETO15980.1 - 1.8 8.2 7.2 7.7 6.2 0.1 2.9 2 1 1 3 3 3 0 Zinc knuckle CDC45 PF02724.9 ETO15981.1 - 0.37 8.7 26.3 0.44 8.5 18.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 ETO15981.1 - 0.55 8.6 37.5 0.64 8.4 26.0 1.1 1 0 0 1 1 1 0 Daxx Family PIG-S PF10510.4 ETO15981.1 - 4.5 5.8 5.8 5.1 5.6 4.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein Ycf1 PF05758.7 ETO15981.1 - 9.9 3.7 19.1 12 3.5 13.2 1.2 1 0 0 1 1 1 0 Ycf1 RhoGEF PF00621.15 ETO15982.1 - 5.5e-18 65.4 1.7 6.5e-18 65.2 1.2 1.1 1 0 0 1 1 1 1 RhoGEF domain CAP_GLY PF01302.20 ETO15983.1 - 3.9e-26 90.5 9.3 1.8e-18 65.9 1.1 2.2 2 0 0 2 2 2 2 CAP-Gly domain EST1 PF10374.4 ETO15984.1 - 0.58 10.1 4.4 9.5 6.2 2.9 2.4 1 1 1 2 2 2 0 Telomerase activating protein Est1 RRM_1 PF00076.17 ETO15985.1 - 7.5e-06 25.4 0.0 0.00018 21.0 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO15985.1 - 0.00016 21.5 0.0 0.00042 20.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETO15985.1 - 0.038 13.7 0.0 0.085 12.6 0.0 1.7 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RasGAP PF00616.14 ETO15988.1 - 0.0081 15.8 2.0 0.016 14.8 1.4 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase Peptidase_S49_N PF08496.5 ETO15988.1 - 0.21 11.3 2.1 0.53 10.0 1.4 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1510 PF07423.6 ETO15988.1 - 1.8 7.8 16.2 0.51 9.6 5.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) POX PF07526.6 ETO15988.1 - 3.5 7.8 14.2 0.56 10.4 2.7 2.4 2 0 0 2 2 2 0 Associated with HOX Eapp_C PF10238.4 ETO15988.1 - 4.7 7.1 14.7 7.1 6.5 3.2 2.7 2 0 0 2 2 2 0 E2F-associated phosphoprotein Mucin PF01456.12 ETO15989.1 - 0.011 15.5 7.5 0.011 15.5 5.2 2.3 3 0 0 3 3 3 0 Mucin-like glycoprotein Dishevelled PF02377.10 ETO15989.1 - 0.28 11.3 6.4 1.4 9.1 4.4 2.2 1 0 0 1 1 1 0 Dishevelled specific domain AIF_C PF14721.1 ETO15989.1 - 0.96 9.6 9.2 2.5 8.3 0.2 2.5 3 0 0 3 3 3 0 Apoptosis-inducing factor, mitochondrion-associated, C-term TMEM51 PF15345.1 ETO15989.1 - 1.5 8.4 14.8 0.37 10.4 0.2 2.7 3 0 0 3 3 3 0 Transmembrane protein 51 Serinc PF03348.10 ETO15989.1 - 3 6.4 5.1 1.4 7.5 0.2 2.0 2 0 0 2 2 2 0 Serine incorporator (Serinc) DUF3753 PF12575.3 ETO15990.1 - 0.28 11.0 3.2 0.59 9.9 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3753) Ribosomal_S25 PF03297.10 ETO15990.1 - 0.38 10.7 3.5 0.88 9.6 2.4 1.7 1 1 0 1 1 1 0 S25 ribosomal protein Amino_oxidase PF01593.19 ETO15991.1 - 8.1e-31 107.5 0.0 3.1e-26 92.4 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase zf-HC5HC2H PF13771.1 ETO15991.1 - 3.2e-07 30.4 5.2 3.2e-07 30.4 3.6 2.0 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 ETO15991.1 - 3.5e-05 23.7 4.9 8.2e-05 22.5 3.4 1.7 1 0 0 1 1 1 1 PHD-zinc-finger like domain XPG_I PF00867.13 ETO15992.1 - 6.4e-31 106.2 0.0 1.8e-30 104.8 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 ETO15992.1 - 6.1e-19 68.1 0.0 1.5e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 ETO15992.1 - 5.8e-10 39.3 0.2 2.4e-09 37.3 0.0 2.1 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.11 ETO15992.1 - 0.0017 17.7 0.0 0.0042 16.4 0.0 1.6 1 1 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain HHH_2 PF12826.2 ETO15992.1 - 0.02 14.7 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF2217 PF10265.4 ETO15993.1 - 0.018 13.7 4.9 0.02 13.6 3.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF3123 PF11321.3 ETO15993.1 - 0.066 13.4 1.8 0.11 12.7 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) Gon7 PF08738.5 ETO15993.1 - 1.2 9.1 11.2 0.16 12.0 4.5 1.9 2 0 0 2 2 2 0 Gon7 family Herpes_UL20 PF04544.7 ETO15994.1 - 0.031 14.0 0.1 0.047 13.5 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus egress protein UL20 DUF3382 PF11862.3 ETO15994.1 - 0.074 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) FH2 PF02181.18 ETO15998.1 - 7e-24 84.3 6.6 8.2e-24 84.1 4.6 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain Glyco_transf_34 PF05637.7 ETO15998.1 - 0.028 13.9 0.7 0.056 12.9 0.4 1.5 1 1 1 2 2 2 0 galactosyl transferase GMA12/MNN10 family FH2 PF02181.18 ETO15999.1 - 1.6e-19 70.0 0.5 1.6e-19 70.0 0.3 2.3 2 0 0 2 2 2 1 Formin Homology 2 Domain Zip PF02535.17 ETO16000.1 - 8.7 5.2 9.3 17 4.3 6.4 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Gemini_mov PF01708.11 ETO16001.1 - 0.13 11.8 0.4 0.31 10.6 0.3 1.6 1 0 0 1 1 1 0 Geminivirus putative movement protein Alba PF01918.16 ETO16002.1 - 6.8e-11 41.6 0.0 1.6e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Alba Rpp20 PF12328.3 ETO16002.1 - 0.011 15.4 1.0 0.018 14.6 0.5 1.5 1 1 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P FANCI_S1-cap PF14674.1 ETO16002.1 - 0.032 14.2 0.0 0.066 13.2 0.0 1.5 1 0 0 1 1 1 0 FANCI solenoid 1 cap WD40 PF00400.27 ETO16003.1 - 9.9e-60 196.4 21.7 6.5e-15 54.3 0.1 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO16003.1 - 1.7e-06 26.4 3.2 0.0046 15.1 0.4 3.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF727 PF05303.7 ETO16003.1 - 1.2e-05 25.0 0.4 2.6 7.8 0.0 4.6 2 1 3 5 5 5 1 Protein of unknown function (DUF727) BBS2_Mid PF14783.1 ETO16003.1 - 3.1e-05 23.6 0.4 0.87 9.3 0.0 3.9 1 1 2 3 3 3 1 Ciliary BBSome complex subunit 2, middle region PD40 PF07676.7 ETO16003.1 - 4.1e-05 23.1 2.0 10 5.8 0.1 5.0 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO16003.1 - 9.6e-05 20.8 0.2 0.0039 15.5 0.0 2.2 1 1 1 2 2 2 1 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 ETO16003.1 - 0.0001 21.5 3.6 2.5 7.5 0.0 5.3 5 0 0 5 5 5 1 Proteasome subunit A N-terminal signature Reg_prop PF07494.6 ETO16003.1 - 0.00081 19.1 0.3 1.5 9.0 0.0 4.3 5 0 0 5 5 4 1 Two component regulator propeller DUF3601 PF12208.3 ETO16003.1 - 0.0071 16.2 0.0 2.3 8.2 0.0 3.7 2 2 2 4 4 4 1 Domain of unknown function (DUF3601) Coatomer_WDAD PF04053.9 ETO16003.1 - 0.016 13.9 0.1 0.022 13.5 0.1 1.3 1 0 0 1 1 1 0 Coatomer WD associated region Ricin_B_lectin PF00652.17 ETO16003.1 - 0.018 15.0 2.2 0.54 10.2 0.0 2.9 1 1 2 3 3 3 0 Ricin-type beta-trefoil lectin domain DUF3312 PF11768.3 ETO16003.1 - 0.025 12.8 0.1 1.2 7.3 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3312) HARP PF07443.8 ETO16003.1 - 0.036 13.4 0.0 13 5.2 0.0 3.7 5 0 0 5 5 5 0 HepA-related protein (HARP) DUF3732 PF12532.3 ETO16003.1 - 0.073 12.5 0.4 1.5 8.2 0.0 2.9 2 2 1 4 4 4 0 Protein of unknown function (DUF3732) Gmad1 PF10647.4 ETO16003.1 - 0.081 12.3 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain DHFR_2 PF06442.6 ETO16003.1 - 0.12 11.9 0.0 12 5.6 0.0 3.3 4 0 0 4 4 4 0 R67 dihydrofolate reductase RRM_5 PF13893.1 ETO16005.1 - 0.0076 16.0 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO16005.1 - 0.012 15.1 0.2 0.049 13.2 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Syntaxin-6_N PF09177.6 ETO16005.1 - 0.013 15.8 6.6 0.013 15.8 4.6 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal RRM_6 PF14259.1 ETO16005.1 - 0.023 14.6 0.0 0.084 12.8 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) V_ATPase_I PF01496.14 ETO16005.1 - 0.22 9.3 10.8 0.34 8.7 7.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CorA PF01544.13 ETO16005.1 - 0.61 9.0 8.9 1.1 8.2 6.2 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein AAA_23 PF13476.1 ETO16005.1 - 2.4 8.4 27.7 5.6 7.2 19.2 1.8 1 1 0 1 1 1 0 AAA domain RRM_1 PF00076.17 ETO16006.1 - 2.8e-08 33.2 0.0 5.8e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO16006.1 - 6.1e-05 22.9 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 ETO16006.1 - 0.093 12.5 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA binding motif DUF973 PF06157.6 ETO16008.1 - 2.2 7.1 18.1 0.3 10.0 4.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF973) DUF872 PF05915.7 ETO16008.1 - 5 7.0 14.2 0.8 9.5 0.4 3.6 3 1 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) DUF1953 PF09196.5 ETO16010.1 - 0.012 15.3 0.2 0.023 14.3 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1953) Cytochrom_D1 PF02239.11 ETO16010.1 - 0.028 12.7 0.0 0.029 12.6 0.0 1.1 1 0 0 1 1 1 0 Cytochrome D1 heme domain TFIIF_alpha PF05793.7 ETO16011.1 - 0.0088 14.4 29.1 0.0092 14.3 20.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MIP-T3 PF10243.4 ETO16011.1 - 0.014 13.8 39.3 0.017 13.6 27.2 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Nop14 PF04147.7 ETO16011.1 - 0.03 12.2 29.1 0.036 12.0 20.2 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 ETO16011.1 - 0.11 11.0 26.1 0.12 10.8 18.1 1.1 1 0 0 1 1 1 0 Daxx Family Utp14 PF04615.8 ETO16011.1 - 0.17 9.9 34.4 0.18 9.8 23.8 1.2 1 0 0 1 1 1 0 Utp14 protein HSP90 PF00183.13 ETO16011.1 - 0.2 10.0 26.0 0.25 9.6 18.0 1.1 1 0 0 1 1 1 0 Hsp90 protein Tim54 PF11711.3 ETO16011.1 - 0.21 10.1 16.4 0.31 9.5 11.3 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.9 ETO16011.1 - 0.23 9.4 25.2 0.28 9.1 17.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF966 PF06136.8 ETO16011.1 - 0.29 10.4 27.1 0.37 10.1 18.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Caldesmon PF02029.10 ETO16011.1 - 0.54 8.6 32.3 0.62 8.4 22.4 1.1 1 0 0 1 1 1 0 Caldesmon SAPS PF04499.10 ETO16011.1 - 0.74 8.3 16.4 0.76 8.3 11.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2146 PF10220.4 ETO16011.1 - 0.78 7.6 23.1 0.92 7.4 16.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) TRAP_alpha PF03896.11 ETO16011.1 - 1.2 8.1 12.3 1.7 7.6 8.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Atrophin-1 PF03154.10 ETO16011.1 - 1.6 6.7 32.8 0.17 9.9 15.2 2.2 2 0 0 2 2 2 0 Atrophin-1 family Trypan_PARP PF05887.6 ETO16011.1 - 1.8 8.4 19.2 2.7 7.8 13.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF572 PF04502.8 ETO16011.1 - 2.3 7.3 31.1 2.9 7.0 21.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF1510 PF07423.6 ETO16011.1 - 3.6 6.9 36.0 5.6 6.2 25.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Borrelia_P83 PF05262.6 ETO16011.1 - 3.9 5.6 21.9 3.9 5.6 15.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DDRGK PF09756.4 ETO16011.1 - 4.3 6.6 35.6 6.6 6.0 24.7 1.2 1 0 0 1 1 1 0 DDRGK domain Otopetrin PF03189.8 ETO16011.1 - 5.4 5.9 9.5 5.9 5.7 6.6 1.2 1 0 0 1 1 1 0 Otopetrin Paramyxo_ncap PF00973.14 ETO16011.1 - 6 5.4 13.9 6.3 5.3 9.6 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CKAP2_C PF15297.1 ETO16011.1 - 8.3 5.1 26.7 13 4.4 18.5 1.3 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Kelch_6 PF13964.1 ETO16012.1 - 8.1e-05 22.6 6.2 4.2 7.7 0.2 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.1 ETO16012.1 - 0.00028 20.5 0.7 0.042 13.6 0.0 3.6 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO16012.1 - 0.0011 18.8 0.2 8.4 6.4 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO16012.1 - 0.029 13.9 6.1 1.2 8.6 0.1 4.4 5 0 0 5 5 5 0 Kelch motif fn3 PF00041.16 ETO16013.1 - 0.00035 20.6 1.0 0.0014 18.7 0.3 2.0 2 0 0 2 2 2 1 Fibronectin type III domain Interfer-bind PF09294.5 ETO16013.1 - 0.2 11.6 3.5 0.23 11.5 0.3 2.1 1 1 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III RGS PF00615.14 ETO16014.1 - 0.0084 16.1 0.9 0.02 14.9 0.6 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain MIG-14_Wnt-bd PF06664.7 ETO16014.1 - 3.8 6.2 30.6 0.8 8.4 3.4 3.3 1 1 1 3 3 3 0 Wnt-binding factor required for Wnt secretion DUF3347 PF11827.3 ETO16015.1 - 0.029 14.3 0.2 0.029 14.3 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) SNARE PF05739.14 ETO16015.1 - 0.19 11.4 2.0 1.6 8.4 0.1 2.3 2 0 0 2 2 2 0 SNARE domain Mnd1 PF03962.10 ETO16015.1 - 0.48 10.0 4.0 0.22 11.1 0.6 1.7 2 0 0 2 2 2 0 Mnd1 family DUF3450 PF11932.3 ETO16015.1 - 7.6 5.7 7.1 0.56 9.4 1.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) WD40 PF00400.27 ETO16018.1 - 7.3e-130 418.7 36.4 2.2e-11 43.1 0.1 16.1 16 0 0 16 16 16 14 WD domain, G-beta repeat PQQ_2 PF13360.1 ETO16018.1 - 3.3e-07 29.9 3.9 0.032 13.7 0.2 5.3 3 3 2 5 5 5 2 PQQ-like domain Pentapeptide PF00805.17 ETO16018.1 - 4.8e-06 25.6 0.1 9.4e-06 24.7 0.1 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 ETO16018.1 - 0.00021 21.1 0.6 0.00072 19.3 0.4 2.0 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.1 ETO16018.1 - 0.00023 20.9 0.9 0.00066 19.4 0.3 2.0 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) PD40 PF07676.7 ETO16018.1 - 0.0014 18.2 21.1 8.2 6.2 0.0 9.1 10 0 0 10 10 9 2 WD40-like Beta Propeller Repeat DUF1938 PF09153.5 ETO16018.1 - 0.0019 18.0 3.2 2 8.2 0.2 5.0 4 1 1 5 5 5 1 Domain of unknown function (DUF1938) Cytochrom_D1 PF02239.11 ETO16018.1 - 0.0023 16.2 10.3 1.5 7.0 0.0 5.4 3 2 3 6 6 6 2 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 ETO16018.1 - 0.025 13.8 3.9 12 5.3 0.0 5.4 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Gmad1 PF10647.4 ETO16018.1 - 0.029 13.7 0.0 1.3 8.3 0.0 3.2 4 0 0 4 4 4 0 Lipoprotein LpqB beta-propeller domain QLQ PF08880.6 ETO16018.1 - 0.34 10.3 2.4 12 5.3 0.1 4.3 4 0 0 4 4 4 0 QLQ Big_2 PF02368.13 ETO16018.1 - 0.87 9.5 4.8 12 5.8 0.2 3.0 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) Sigma70_ner PF04546.8 ETO16020.1 - 0.018 14.6 3.3 0.022 14.3 2.3 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.6 ETO16020.1 - 0.041 13.6 3.0 0.066 13.0 2.0 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal DEAD PF00270.24 ETO16020.1 - 0.052 13.0 0.0 0.093 12.2 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase F-protein PF00469.15 ETO16020.1 - 0.2 11.0 0.0 0.2 11.0 0.0 2.0 1 1 1 2 2 2 0 Negative factor, (F-Protein) or Nef FAM176 PF14851.1 ETO16020.1 - 0.42 10.2 2.5 0.52 9.9 1.7 1.2 1 0 0 1 1 1 0 FAM176 family ResIII PF04851.10 ETO16020.1 - 0.9 9.3 4.1 2.3 8.0 0.1 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit SAYSvFN PF10260.4 ETO16022.1 - 0.03 14.1 0.5 0.86 9.4 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) DUF1345 PF07077.6 ETO16022.1 - 0.061 12.8 1.7 0.07 12.6 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1345) DUF202 PF02656.10 ETO16022.1 - 0.52 10.5 2.4 25 5.2 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF2701 PF10857.3 ETO16022.1 - 3.5 7.4 6.7 22 4.8 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2701) DUF1681 PF07933.9 ETO16023.1 - 9e-20 70.8 0.1 9e-20 70.8 0.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1681) RFC1 PF08519.7 ETO16024.1 - 0.021 14.5 2.7 0.042 13.5 1.9 1.5 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain FANCI_S3 PF14677.1 ETO16024.1 - 0.035 13.5 0.6 0.058 12.7 0.4 1.3 1 0 0 1 1 1 0 FANCI solenoid 3 Mitofilin PF09731.4 ETO16024.1 - 0.085 11.5 1.5 0.13 10.9 1.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein adh_short PF00106.20 ETO16025.1 - 0.013 15.3 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase Sec23_helical PF04815.10 ETO16025.1 - 0.086 12.2 0.2 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 Sec23/Sec24 helical domain WD40 PF00400.27 ETO16026.1 - 2.1e-07 30.5 0.0 3.4e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 WD domain, G-beta repeat WD40 PF00400.27 ETO16027.1 - 6.4e-36 120.9 6.4 1.7e-11 43.5 0.2 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 ETO16027.1 - 0.011 15.4 0.0 0.35 10.5 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Ribosomal_S14 PF00253.16 ETO16027.1 - 0.099 12.0 0.0 2.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e RdRP PF05183.7 ETO16028.1 - 1.1e-20 73.9 0.0 1.4e-20 73.5 0.0 1.0 1 0 0 1 1 1 1 RNA dependent RNA polymerase ODV-E18 PF10717.4 ETO16028.1 - 0.0066 15.8 1.8 0.011 15.1 1.3 1.3 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 ASFV_J13L PF05568.6 ETO16028.1 - 0.021 14.3 3.3 0.031 13.8 2.3 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF2976 PF11190.3 ETO16028.1 - 1.7 8.2 6.2 3.5 7.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) DUF3139 PF11337.3 ETO16028.1 - 1.9 8.8 11.1 0.81 10.0 5.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Sigma_reg_N PF13800.1 ETO16028.1 - 3.5 7.7 7.8 6.8 6.7 5.4 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF4363 PF14276.1 ETO16028.1 - 7.9 6.2 8.1 54 3.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) FtsX PF02687.16 ETO16029.1 - 0.059 13.1 0.2 0.084 12.6 0.2 1.1 1 0 0 1 1 1 0 FtsX-like permease family Daxx PF03344.10 ETO16029.1 - 0.08 11.4 14.1 0.099 11.1 9.7 1.0 1 0 0 1 1 1 0 Daxx Family Zip PF02535.17 ETO16029.1 - 0.09 11.7 1.9 0.62 9.0 1.3 2.0 1 1 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.9 ETO16029.1 - 7.6 4.4 16.4 10 4.0 11.4 1.1 1 0 0 1 1 1 0 CDC45-like protein U79_P34 PF03064.11 ETO16031.1 - 0.46 9.9 5.9 0.58 9.6 4.1 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF489 PF04356.7 ETO16032.1 - 0.0097 15.5 4.3 0.012 15.2 2.8 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF489) EzrA PF06160.7 ETO16032.1 - 0.17 10.0 17.2 0.056 11.6 9.8 1.5 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA DUF745 PF05335.8 ETO16032.1 - 0.26 10.8 13.0 0.084 12.3 5.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Atg14 PF10186.4 ETO16032.1 - 0.59 9.0 14.6 0.92 8.3 10.1 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Sec20 PF03908.8 ETO16032.1 - 6.5 6.5 11.2 14 5.4 3.8 2.4 1 1 1 2 2 2 0 Sec20 RRM_6 PF14259.1 ETO16034.1 - 8.2e-07 28.9 0.0 1.8e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO16034.1 - 0.014 15.0 0.0 0.031 13.8 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3439 PF11921.3 ETO16034.1 - 0.89 9.3 11.4 0.075 12.7 3.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) FimP PF09766.4 ETO16035.1 - 0.00097 18.2 8.2 0.00097 18.2 5.7 2.1 2 1 0 2 2 2 1 Fms-interacting protein Tox-PLDMTX PF15645.1 ETO16035.1 - 0.01 15.8 0.5 0.01 15.8 0.4 1.9 2 1 0 2 2 2 0 Dermonecrotoxin of the Papain-like fold Mt_ATP-synt_D PF05873.7 ETO16035.1 - 0.01 15.4 2.5 0.023 14.3 1.7 1.6 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) DASH_Spc19 PF08287.6 ETO16035.1 - 0.049 13.2 0.4 0.049 13.2 0.3 2.8 2 1 1 3 3 3 0 Spc19 DUF972 PF06156.8 ETO16035.1 - 0.051 13.9 1.1 0.051 13.9 0.8 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Chibby PF14645.1 ETO16035.1 - 0.067 13.0 5.5 0.23 11.3 3.8 1.9 1 0 0 1 1 1 0 Chibby family Allexi_40kDa PF05549.6 ETO16035.1 - 0.15 11.3 13.3 0.1 11.8 2.0 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein GAS PF13851.1 ETO16035.1 - 0.24 10.5 29.5 0.26 10.4 14.2 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1874 PF08960.5 ETO16035.1 - 0.31 10.7 6.3 0.23 11.2 0.5 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1874) Fmp27_WPPW PF10359.4 ETO16035.1 - 0.38 9.1 17.4 0.4 9.0 6.9 2.1 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Uds1 PF15456.1 ETO16035.1 - 0.69 9.9 18.7 3.2 7.7 8.7 2.3 2 0 0 2 2 2 0 Up-regulated During Septation ADIP PF11559.3 ETO16035.1 - 2.8 7.8 27.7 0.31 10.9 2.5 2.9 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF87 PF01935.12 ETO16035.1 - 2.9 7.6 8.8 1.1 9.0 2.5 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF3300 PF11737.3 ETO16035.1 - 4.5 6.4 7.0 7.5 5.7 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3300) DivIVA PF05103.8 ETO16035.1 - 7 6.7 25.9 1.5 8.8 0.9 2.6 2 1 0 2 2 2 0 DivIVA protein IMS PF00817.15 ETO16036.1 - 1.2e-16 60.8 0.0 2.7e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family CRAL_TRIO PF00650.15 ETO16036.1 - 0.019 14.4 0.0 0.046 13.2 0.0 1.6 1 0 0 1 1 1 0 CRAL/TRIO domain IMS_HHH PF11798.3 ETO16036.1 - 0.022 14.7 0.1 0.055 13.5 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif PAM2 PF07145.10 ETO16037.1 - 0.76 9.4 4.4 0.82 9.3 0.9 2.2 2 0 0 2 2 2 0 Ataxin-2 C-terminal region SDA1 PF05285.7 ETO16038.1 - 5.6 6.1 9.9 7.5 5.7 6.9 1.2 1 0 0 1 1 1 0 SDA1 Arm PF00514.18 ETO16039.1 - 0.063 13.1 0.2 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat Alginate_lyase PF05426.7 ETO16042.1 - 0.012 15.0 12.2 0.027 13.8 2.1 2.2 1 1 0 2 2 2 0 Alginate lyase Prog_receptor PF02161.10 ETO16042.1 - 0.23 10.2 1.4 0.29 9.9 1.0 1.0 1 0 0 1 1 1 0 Progesterone receptor IFRD PF05004.8 ETO16042.1 - 0.34 9.9 4.2 3.4 6.6 0.2 2.3 2 1 0 2 2 2 0 Interferon-related developmental regulator (IFRD) Spore_coat_CotO PF14153.1 ETO16042.1 - 4.8 6.5 14.0 6.9 6.0 9.7 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Apis_Csd PF11671.3 ETO16044.1 - 6.5 6.5 8.4 8.8 6.1 2.8 2.3 2 0 0 2 2 2 0 Complementary sex determiner protein FIST PF08495.5 ETO16045.1 - 0.056 12.5 0.9 0.096 11.8 0.6 1.4 1 0 0 1 1 1 0 FIST N domain ECIST_Cterm PF14784.1 ETO16045.1 - 0.13 12.1 5.2 0.098 12.6 1.1 2.5 2 0 0 2 2 2 0 C-terminal domain of the ECSIT protein DUF972 PF06156.8 ETO16045.1 - 0.55 10.6 27.8 0.31 11.3 3.5 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF972) APG6 PF04111.7 ETO16045.1 - 1.1 8.2 33.5 1.6 7.7 8.4 2.8 2 1 0 2 2 2 0 Autophagy protein Apg6 Myco_19_kDa PF05481.7 ETO16045.1 - 4.7 7.0 8.6 13 5.5 5.9 1.7 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen Tropomyosin_1 PF12718.2 ETO16045.1 - 4.7 7.0 36.5 6 6.7 8.4 2.4 2 0 0 2 2 2 0 Tropomyosin like Seryl_tRNA_N PF02403.17 ETO16045.1 - 5.3 7.0 21.5 9.6 6.2 3.7 3.3 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF948 PF06103.6 ETO16045.1 - 5.9 6.8 8.5 2.5 8.0 0.5 3.3 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) mRNA_cap_C PF03919.10 ETO16045.1 - 6.9 7.0 10.6 0.35 11.2 0.5 3.1 2 1 0 2 2 2 0 mRNA capping enzyme, C-terminal domain UPF0160 PF03690.8 ETO16046.1 - 2.8e-57 194.5 0.0 3.3e-57 194.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) UAA PF08449.6 ETO16047.1 - 8.3e-36 123.4 19.4 9.7e-36 123.2 13.4 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 ETO16047.1 - 0.00035 20.5 7.6 0.00035 20.5 5.2 2.3 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 ETO16047.1 - 0.047 13.3 18.6 0.63 9.6 1.3 2.4 2 0 0 2 2 2 0 Triose-phosphate Transporter family CYSTM PF12734.2 ETO16047.1 - 0.41 10.7 3.8 1.6 8.8 0.1 2.4 2 0 0 2 2 2 0 Cysteine-rich TM module stress tolerance Fumarate_red_C PF02300.12 ETO16047.1 - 2 8.2 10.8 0.051 13.4 0.5 3.0 3 1 1 4 4 4 0 Fumarate reductase subunit C U-box PF04564.10 ETO16048.1 - 5.5e-09 35.8 0.0 8.3e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 U-box domain CMD PF02627.15 ETO16049.1 - 1.1e-08 34.7 0.1 1.9e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family zf-MIZ PF02891.15 ETO16050.1 - 2.2e-16 59.0 9.8 2.2e-16 59.0 6.8 2.3 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-MYND PF01753.13 ETO16050.1 - 1.8e-08 34.1 11.3 1.8e-08 34.1 7.8 2.1 2 0 0 2 2 2 1 MYND finger zf-Nse PF11789.3 ETO16050.1 - 0.00029 20.2 1.9 0.0011 18.4 1.3 2.0 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit WD40 PF00400.27 ETO16051.1 - 6.3e-48 159.0 27.2 6.8e-13 47.9 0.1 7.8 7 1 1 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO16051.1 - 4.8e-13 48.1 0.4 0.00012 20.3 0.0 4.9 1 1 3 4 4 4 4 Nucleoporin Nup120/160 GTP_EFTU_D2 PF03144.20 ETO16052.1 - 0.0015 18.5 0.0 0.0084 16.1 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu domain 2 ATAD4 PF15321.1 ETO16052.1 - 7.5 7.6 11.4 1.4 9.9 3.7 2.5 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 CDC45 PF02724.9 ETO16053.1 - 9.5 4.1 13.0 12 3.8 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Cnd1_N PF12922.2 ETO16056.1 - 0.039 13.5 0.1 0.093 12.3 0.1 1.6 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term PUB PF09409.5 ETO16057.1 - 6.7e-09 35.3 0.0 1.8e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 PUB domain Viral_Beta_CD PF04530.7 ETO16057.1 - 1.7 8.7 6.1 0.42 10.7 0.0 2.9 3 0 0 3 3 3 0 Viral Beta C/D like family Fringe PF02434.11 ETO16059.1 - 6.1e-05 22.3 0.1 0.00013 21.2 0.1 1.5 1 1 0 1 1 1 1 Fringe-like WD40 PF00400.27 ETO16060.1 - 2.4e-30 103.2 10.8 3.8e-10 39.2 0.7 5.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO16060.1 - 5.8e-05 21.4 2.3 0.28 9.2 0.0 3.9 2 1 2 4 4 4 4 Nucleoporin Nup120/160 DUF4603 PF15376.1 ETO16061.1 - 0.0027 14.9 3.3 0.0034 14.6 2.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4603) Ribosomal_L15e PF00827.12 ETO16061.1 - 0.031 13.7 0.1 0.04 13.4 0.1 1.1 1 0 0 1 1 1 0 Ribosomal L15 ApoO PF09769.4 ETO16061.1 - 0.032 13.9 0.8 0.046 13.4 0.5 1.3 1 0 0 1 1 1 0 Apolipoprotein O NRDE-2 PF08424.5 ETO16061.1 - 0.039 12.8 1.3 0.046 12.5 0.9 1.0 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference XAP5 PF04921.9 ETO16061.1 - 0.071 12.6 4.5 0.095 12.2 3.1 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator DUF3548 PF12068.3 ETO16061.1 - 0.44 9.8 4.8 0.56 9.4 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3548) Methyltransf_26 PF13659.1 ETO16065.1 - 0.005 16.8 0.0 0.0075 16.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 ETO16065.1 - 0.066 12.7 0.1 0.14 11.7 0.0 1.5 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 tRNA_bind_2 PF13725.1 ETO16066.1 - 0.037 14.1 0.0 0.092 12.8 0.0 1.6 1 0 0 1 1 1 0 Possible tRNA binding domain TPR_14 PF13428.1 ETO16066.1 - 0.17 12.6 0.0 5.1 8.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat PP2C PF00481.16 ETO16067.1 - 4e-18 65.7 0.1 5.4e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 ETO16067.1 - 0.0002 20.8 0.4 0.00034 20.1 0.3 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C Arif-1 PF06770.6 ETO16068.1 - 0.058 12.7 0.3 0.22 10.8 0.0 1.8 2 0 0 2 2 2 0 Actin-rearrangement-inducing factor (Arif-1) WD40 PF00400.27 ETO16069.1 - 2.6e-59 195.0 26.8 8.9e-11 41.2 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO16069.1 - 1.8e-13 49.4 1.7 0.0025 16.0 0.1 5.6 1 1 3 6 6 6 5 Nucleoporin Nup120/160 HAD PF12710.2 ETO16069.1 - 0.12 12.5 1.9 2 8.5 1.3 2.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Met_synt_B12 PF02965.12 ETO16071.1 - 0.0052 15.9 0.1 0.0064 15.7 0.1 1.1 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain BTV_NS2 PF04514.7 ETO16071.1 - 0.089 11.6 14.2 0.1 11.4 9.9 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CCDC142 PF14923.1 ETO16071.1 - 0.1 10.8 1.4 0.12 10.6 0.9 1.2 1 0 0 1 1 1 0 Coiled-coil protein 142 SPX PF03105.14 ETO16071.1 - 0.11 12.2 11.4 0.14 11.8 7.9 1.3 1 0 0 1 1 1 0 SPX domain CobT PF06213.7 ETO16071.1 - 0.35 9.9 15.0 0.41 9.7 10.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FLO_LFY PF01698.11 ETO16071.1 - 0.42 9.4 8.6 0.48 9.2 5.9 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein NARP1 PF12569.3 ETO16071.1 - 0.45 9.2 8.0 0.16 10.7 4.1 1.3 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 DUF2457 PF10446.4 ETO16071.1 - 0.53 8.9 18.0 0.62 8.7 12.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 ETO16071.1 - 0.61 8.4 14.9 0.64 8.4 10.4 1.1 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 ETO16071.1 - 0.68 9.2 14.9 0.94 8.7 10.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) ATAD4 PF15321.1 ETO16071.1 - 2.7 9.0 11.0 0.18 12.8 0.6 2.2 1 1 1 2 2 2 0 ATPase family AAA domain containing 4 Menin PF05053.8 ETO16071.1 - 2.7 6.0 8.0 3.1 5.8 5.6 1.1 1 0 0 1 1 1 0 Menin RRN3 PF05327.6 ETO16071.1 - 4 5.4 8.0 4.3 5.3 5.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Astro_capsid PF03115.9 ETO16071.1 - 5.3 5.1 9.0 5.9 5.0 6.2 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor NOA36 PF06524.7 ETO16071.1 - 5.4 6.1 13.5 6.6 5.9 9.4 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 ETO16071.1 - 7.3 4.4 13.3 8.5 4.2 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein S-antigen PF05756.6 ETO16071.1 - 8.6 6.4 12.8 18 5.3 8.9 1.6 1 0 0 1 1 1 0 S-antigen protein GCIP PF13324.1 ETO16071.1 - 9.2 5.3 9.5 8.2 5.5 6.0 1.4 1 1 0 1 1 1 0 Grap2 and cyclin-D-interacting UCH PF00443.24 ETO16072.1 - 9.7e-13 47.8 0.5 1.7e-12 47.0 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CAP_GLY PF01302.20 ETO16073.1 - 2.3e-13 49.6 1.7 2.3e-13 49.6 1.2 1.6 2 0 0 2 2 2 1 CAP-Gly domain FNIP PF05725.7 ETO16073.1 - 0.037 13.9 0.3 10 6.1 0.1 2.5 2 0 0 2 2 2 0 FNIP Repeat GNT-I PF03071.10 ETO16073.1 - 0.13 10.7 0.5 0.37 9.2 0.1 1.8 1 1 1 2 2 2 0 GNT-I family CAP_GLY PF01302.20 ETO16074.1 - 2.7e-52 174.3 12.9 7.2e-14 51.2 0.0 5.3 5 0 0 5 5 5 5 CAP-Gly domain YajC PF02699.10 ETO16074.1 - 0.13 11.9 2.4 5.2 6.8 0.1 3.0 3 0 0 3 3 3 0 Preprotein translocase subunit CAP_GLY PF01302.20 ETO16075.1 - 2e-12 46.6 0.1 7.6e-10 38.3 0.0 2.4 2 0 0 2 2 2 2 CAP-Gly domain SspB PF04386.8 ETO16075.1 - 0.18 11.3 2.0 0.38 10.3 1.4 1.4 1 0 0 1 1 1 0 Stringent starvation protein B V_ATPase_I PF01496.14 ETO16075.1 - 3.3 5.4 5.6 0.14 9.9 0.1 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family TFIIA PF03153.8 ETO16076.1 - 0.45 10.3 19.2 0.5 10.1 13.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ATG16 PF08614.6 ETO16076.1 - 0.62 9.8 10.1 0.8 9.4 7.0 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) SurA_N PF09312.6 ETO16076.1 - 3.2 7.6 10.0 4 7.3 6.2 1.6 1 1 0 1 1 1 0 SurA N-terminal domain Host_attach PF10116.4 ETO16076.1 - 5 7.3 7.0 4.2 7.6 3.7 1.7 1 1 1 2 2 2 0 Protein required for attachment to host cells Lin-8 PF03353.10 ETO16076.1 - 9 5.4 10.1 11 5.1 7.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PAT1 PF09770.4 ETO16076.1 - 9.4 4.3 21.7 9.6 4.2 15.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Proteasom_Rpn13 PF04683.8 ETO16077.1 - 1.2e-19 70.1 2.7 2.4e-15 56.3 0.4 3.3 2 1 0 2 2 2 2 Proteasome complex subunit Rpn13 ubiquitin receptor TRM13 PF05206.9 ETO16077.1 - 0.018 14.2 1.1 0.029 13.5 0.8 1.3 1 0 0 1 1 1 0 Methyltransferase TRM13 NST1 PF13945.1 ETO16077.1 - 0.031 14.3 1.1 0.031 14.3 0.8 2.3 2 0 0 2 2 2 0 Salt tolerance down-regulator KSHV_K1 PF11049.3 ETO16077.1 - 0.13 12.2 0.1 0.34 10.9 0.1 1.7 1 0 0 1 1 1 0 Glycoprotein K1 of Kaposi's sarcoma-associated herpes virus DUF2250 PF10007.4 ETO16077.1 - 0.35 10.8 3.9 0.72 9.7 2.7 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) ETRAMP PF09716.5 ETO16077.1 - 2.4 8.1 6.2 12 5.9 0.1 2.5 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) TraG_N PF07916.6 ETO16079.1 - 0.1 11.0 0.1 0.21 9.9 0.0 1.4 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Reo_sigmaC PF04582.7 ETO16079.1 - 8 5.5 12.2 4.9 6.2 0.7 3.9 3 1 1 4 4 4 0 Reovirus sigma C capsid protein IF3_C PF00707.17 ETO16081.1 - 0.039 13.6 0.1 0.081 12.6 0.1 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-3, C-terminal domain IL8 PF00048.15 ETO16081.1 - 0.12 12.3 5.7 0.16 11.9 2.8 2.0 2 0 0 2 2 2 0 Small cytokines (intecrine/chemokine), interleukin-8 like Pkinase PF00069.20 ETO16082.1 - 1.7e-41 142.1 1.1 3.4e-41 141.1 0.8 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO16082.1 - 1.5e-09 37.2 0.2 5.8e-09 35.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Shigella_OspC PF06128.6 ETO16082.1 - 0.0014 18.1 0.7 0.0024 17.4 0.5 1.3 1 0 0 1 1 1 1 Shigella flexneri OspC protein Choline_transpo PF04515.7 ETO16083.1 - 0.0065 15.2 0.3 0.18 10.4 0.1 2.0 2 0 0 2 2 2 2 Plasma-membrane choline transporter TROVE PF05731.6 ETO16083.1 - 0.095 11.4 7.0 0.13 10.9 4.9 1.1 1 0 0 1 1 1 0 TROVE domain PhoQ_Sensor PF08918.5 ETO16083.1 - 0.28 10.6 2.0 0.41 10.1 1.4 1.2 1 0 0 1 1 1 0 PhoQ Sensor Herpes_UL21 PF03252.8 ETO16084.1 - 0.038 12.4 0.0 0.05 12.0 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL21 Innate_immun PF12782.2 ETO16084.1 - 1.8 7.7 9.6 3 6.9 6.6 1.4 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family DUF912 PF06024.7 ETO16086.1 - 0.58 10.2 0.0 0.58 10.2 0.0 3.0 3 1 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2615 PF11027.3 ETO16086.1 - 2.1 8.3 4.7 12 5.8 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2615) SecD_SecF PF02355.11 ETO16086.1 - 5.4 6.1 12.3 0.7 9.0 2.6 2.9 3 0 0 3 3 3 0 Protein export membrane protein SHIPPO-rpt PF07004.7 ETO16087.1 - 1.1 10.3 4.9 3.1 8.8 0.3 3.2 3 0 0 3 3 3 0 Sperm-tail PG-rich repeat His_Phos_1 PF00300.17 ETO16088.1 - 1.8e-25 89.8 0.0 2.7e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) TPR_11 PF13414.1 ETO16089.1 - 7.5e-06 25.5 5.6 0.63 9.7 0.0 4.4 3 1 1 4 4 4 2 TPR repeat TPR_12 PF13424.1 ETO16089.1 - 0.00032 20.5 6.0 0.98 9.4 0.6 4.0 4 1 0 4 4 4 2 Tetratricopeptide repeat Pox_A3L PF05288.6 ETO16089.1 - 0.015 14.9 0.1 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A3L Protein TPR_2 PF07719.12 ETO16089.1 - 0.13 12.2 10.6 2.2 8.4 0.0 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat YL1 PF05764.8 ETO16091.1 - 0.014 15.0 20.0 0.015 14.9 13.9 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DUF4366 PF14283.1 ETO16091.1 - 0.014 14.8 3.6 0.015 14.7 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) 7tm_6 PF02949.15 ETO16091.1 - 0.059 12.2 0.2 0.066 12.0 0.1 1.2 1 0 0 1 1 1 0 7tm Odorant receptor TRAP_alpha PF03896.11 ETO16091.1 - 0.065 12.2 4.6 0.07 12.1 3.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Myc_N PF01056.13 ETO16091.1 - 0.065 12.3 6.4 0.064 12.4 4.4 1.1 1 0 0 1 1 1 0 Myc amino-terminal region RNA_polI_A34 PF08208.6 ETO16091.1 - 0.07 12.7 16.6 0.074 12.7 11.5 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Glyco_hydro_65N PF03636.10 ETO16091.1 - 0.081 12.2 1.5 0.093 12.0 1.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain HSP90 PF00183.13 ETO16091.1 - 0.19 10.1 13.9 0.2 10.0 9.6 1.2 1 0 0 1 1 1 0 Hsp90 protein Sporozoite_P67 PF05642.6 ETO16091.1 - 0.37 8.6 4.2 0.37 8.5 2.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Serinc PF03348.10 ETO16091.1 - 0.62 8.7 3.6 0.65 8.6 2.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Peroxin-13_N PF04088.8 ETO16091.1 - 0.81 9.6 3.7 0.68 9.8 1.8 1.4 1 1 0 1 1 1 0 Peroxin 13, N-terminal region DUF4604 PF15377.1 ETO16091.1 - 0.98 9.6 14.5 1.2 9.3 10.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) SOBP PF15279.1 ETO16091.1 - 1.3 9.3 7.1 1.2 9.4 4.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein SspB PF04386.8 ETO16091.1 - 1.3 8.5 6.1 1.7 8.2 4.2 1.3 1 0 0 1 1 1 0 Stringent starvation protein B Prog_receptor PF02161.10 ETO16091.1 - 1.6 7.4 4.0 1.6 7.4 2.7 1.0 1 0 0 1 1 1 0 Progesterone receptor DUF4557 PF15101.1 ETO16091.1 - 1.8 8.3 7.4 2 8.2 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Ribosomal_60s PF00428.14 ETO16091.1 - 3.7 8.0 10.2 0.1 13.0 2.8 1.6 2 0 0 2 2 1 0 60s Acidic ribosomal protein DDHD PF02862.12 ETO16091.1 - 6.6 6.4 8.0 6.9 6.3 5.5 1.2 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.9 ETO16091.1 - 7.4 4.4 15.7 7.1 4.5 10.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Tom37_C PF11801.3 ETO16091.1 - 8 6.3 10.0 10 5.9 6.9 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain EF-hand_1 PF00036.27 ETO16092.1 - 1e-11 43.2 8.1 1.7e-05 23.7 0.7 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 ETO16092.1 - 2.8e-10 40.1 4.1 6.6e-10 38.9 2.8 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO16092.1 - 2.6e-09 36.2 4.9 0.00022 20.8 0.4 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 ETO16092.1 - 0.0001 21.4 6.4 0.0013 17.9 0.4 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 ETO16092.1 - 0.00016 21.1 5.1 0.0089 15.6 0.7 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_10 PF14788.1 ETO16092.1 - 0.011 15.3 3.4 2.2 7.9 0.3 2.4 2 0 0 2 2 2 0 EF hand Raftlin PF15250.1 ETO16092.1 - 0.96 7.9 9.3 1.1 7.6 6.4 1.1 1 0 0 1 1 1 0 Raftlin SPARC_Ca_bdg PF10591.4 ETO16092.1 - 1.1 9.3 14.1 8.8 6.3 9.8 2.1 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region YABBY PF04690.8 ETO16092.1 - 2 8.6 6.1 2.5 8.3 4.2 1.1 1 0 0 1 1 1 0 YABBY protein Vfa1 PF08432.5 ETO16092.1 - 9.3 6.2 17.8 12 5.8 12.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Polyoma_lg_T_C PF06431.6 ETO16093.1 - 0.014 14.0 0.3 0.021 13.5 0.2 1.3 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus SDA1 PF05285.7 ETO16093.1 - 0.041 13.1 7.7 0.052 12.8 5.4 1.1 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.4 ETO16093.1 - 0.23 10.1 7.4 0.29 9.8 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FAM176 PF14851.1 ETO16093.1 - 0.24 11.0 2.5 0.28 10.8 0.3 1.9 2 0 0 2 2 2 0 FAM176 family BUD22 PF09073.5 ETO16093.1 - 0.35 9.8 9.0 0.44 9.5 6.2 1.1 1 0 0 1 1 1 0 BUD22 Myc_N PF01056.13 ETO16093.1 - 0.64 9.1 5.8 1 8.4 4.0 1.3 1 0 0 1 1 1 0 Myc amino-terminal region CDC45 PF02724.9 ETO16093.1 - 0.88 7.5 8.9 0.15 10.0 3.7 1.5 2 0 0 2 2 2 0 CDC45-like protein PPI_Ypi1 PF07491.6 ETO16093.1 - 2.7 7.6 7.7 1.4e+02 2.1 0.0 3.4 3 0 0 3 3 3 0 Protein phosphatase inhibitor Tom22 PF04281.8 ETO16093.1 - 3.3 7.2 7.8 1.4 8.4 3.1 2.0 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 AF-4 PF05110.8 ETO16093.1 - 3.6 5.3 11.2 4.7 4.9 7.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Cwf_Cwc_15 PF04889.7 ETO16093.1 - 4.7 6.8 12.3 0.99 9.0 5.5 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Pyridox_oxidase PF01243.15 ETO16094.1 - 3.4e-13 49.4 0.0 1.2e-12 47.7 0.0 1.9 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 ETO16094.1 - 5.4e-05 23.4 0.1 0.00025 21.3 0.0 2.3 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase WD40 PF00400.27 ETO16095.1 - 8.1e-56 184.0 19.4 3.9e-10 39.2 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO16095.1 - 2.6e-10 39.0 8.9 0.0033 15.6 0.1 5.0 2 2 1 4 4 4 4 Nucleoporin Nup120/160 DWNN PF08783.6 ETO16096.1 - 0.32 10.9 3.0 0.58 10.1 2.1 1.5 1 0 0 1 1 1 0 DWNN domain OST-HTH PF12872.2 ETO16097.1 - 0.00034 20.4 0.0 1.5 8.7 0.0 3.5 3 1 0 3 3 3 2 OST-HTH/LOTUS domain DUF2796 PF10986.3 ETO16097.1 - 0.014 15.3 9.6 0.026 14.4 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Peptidase_S49_N PF08496.5 ETO16097.1 - 2.6 7.8 4.9 5 6.8 3.4 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Pox_Ag35 PF03286.9 ETO16097.1 - 4.9 6.6 15.4 10 5.5 10.7 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM176 PF14851.1 ETO16097.1 - 6.4 6.4 7.6 14 5.3 5.3 1.5 1 0 0 1 1 1 0 FAM176 family Kelch_6 PF13964.1 ETO16099.1 - 2.1e-07 30.8 2.1 0.034 14.3 0.0 4.5 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO16099.1 - 4e-07 29.4 1.7 0.017 14.6 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO16099.1 - 0.00036 20.1 1.5 1.3 8.9 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO16099.1 - 0.0071 16.0 0.5 0.14 11.9 0.0 3.4 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO16099.1 - 0.016 15.1 0.1 14 5.8 0.0 3.5 4 0 0 4 4 4 0 Kelch motif N_Asn_amidohyd PF14736.1 ETO16099.1 - 0.024 13.5 0.0 1.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein N-terminal asparagine amidohydrolase WD40 PF00400.27 ETO16100.1 - 3.1e-41 137.8 13.5 7e-12 44.7 0.4 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat Tub_2 PF04525.7 ETO16100.1 - 0.0033 16.8 0.4 0.12 11.7 0.0 2.3 2 0 0 2 2 2 1 Tubby C 2 Nucleoporin_N PF08801.6 ETO16100.1 - 0.027 13.2 7.5 2.7 6.6 0.2 3.6 1 1 2 3 3 3 0 Nup133 N terminal like OstA_2 PF13100.1 ETO16100.1 - 0.04 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 OstA-like protein GDPD PF03009.12 ETO16100.1 - 0.052 13.0 0.0 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family DUF1652 PF07865.6 ETO16100.1 - 0.12 11.9 0.0 1.2 8.7 0.0 2.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1652) Kelch_1 PF01344.20 ETO16101.1 - 0.0006 19.2 8.0 0.011 15.2 0.0 4.7 4 1 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 ETO16101.1 - 0.00074 19.5 5.3 0.098 12.8 0.0 4.2 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO16101.1 - 0.01 15.5 5.7 0.46 10.3 0.1 4.1 4 0 0 4 4 4 0 Kelch motif Toprim_2 PF13155.1 ETO16102.1 - 0.14 12.4 0.3 0.14 12.4 0.2 2.8 3 0 0 3 3 3 0 Toprim-like ATP-synt_E PF05680.7 ETO16102.1 - 6.7 6.7 22.7 1.5 8.8 2.0 3.6 3 0 0 3 3 3 0 ATP synthase E chain ScpA_ScpB PF02616.9 ETO16103.1 - 0.72 9.3 7.4 1 8.8 5.1 1.1 1 0 0 1 1 1 0 ScpA/B protein Band_3_cyto PF07565.8 ETO16103.1 - 1.3 8.4 8.5 0.17 11.4 3.2 1.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF3959 PF13105.1 ETO16103.1 - 2.5 7.3 4.1 3.6 6.8 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) RP-C_C PF11800.3 ETO16103.1 - 3.9 7.1 10.5 0.16 11.6 3.2 1.7 2 0 0 2 2 2 0 Replication protein C C-terminal region DUF3245 PF11595.3 ETO16103.1 - 7.6 6.8 11.1 0.84 9.9 4.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Pkinase PF00069.20 ETO16104.1 - 3.1e-38 131.4 0.1 5.7e-26 91.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO16104.1 - 3.6e-27 95.0 0.0 5.9e-20 71.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase PMG PF05287.7 ETO16104.1 - 0.0001 22.1 0.7 0.00014 21.7 0.5 1.1 1 0 0 1 1 1 1 PMG protein DUF3753 PF12575.3 ETO16104.1 - 0.0067 16.2 2.1 0.012 15.3 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3753) APH PF01636.18 ETO16104.1 - 0.034 13.8 0.0 0.06 13.0 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family PIP49_C PF12260.3 ETO16104.1 - 0.044 13.2 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 ODV-E18 PF10717.4 ETO16104.1 - 0.1 12.0 1.6 0.29 10.6 1.1 1.7 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 ATG27 PF09451.5 ETO16104.1 - 0.2 10.8 3.5 0.39 9.8 2.4 1.4 1 0 0 1 1 1 0 Autophagy-related protein 27 TMEM154 PF15102.1 ETO16104.1 - 1.4 8.6 4.3 0.83 9.3 1.0 1.9 2 0 0 2 2 2 0 TMEM154 protein family DUF1833 PF08875.6 ETO16105.1 - 0.063 12.4 0.3 0.1 11.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1833) Acyl-ACP_TE PF01643.12 ETO16106.1 - 0.01 14.7 0.1 0.022 13.7 0.1 1.6 1 0 0 1 1 1 0 Acyl-ACP thioesterase BTB PF00651.26 ETO16107.1 - 1.1e-20 73.6 0.3 1.1e-20 73.6 0.2 2.8 3 0 0 3 3 3 2 BTB/POZ domain Transglut_core PF01841.14 ETO16109.1 - 0.00035 20.7 0.0 0.0031 17.7 0.0 2.1 2 0 0 2 2 2 1 Transglutaminase-like superfamily BHD_3 PF10405.4 ETO16110.1 - 3.7e-21 74.6 0.0 9.6e-21 73.2 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 ETO16110.1 - 5.6e-13 48.1 1.0 1.1e-12 47.2 0.7 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Rad4 PF03835.10 ETO16110.1 - 7.2e-13 48.1 0.5 1.4e-12 47.2 0.4 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_2 PF10404.4 ETO16110.1 - 9e-09 35.5 0.2 2.3e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 LicD PF04991.8 ETO16110.1 - 0.086 12.9 0.6 0.16 12.0 0.4 1.4 1 0 0 1 1 1 0 LicD family Pyr_redox_dim PF02852.17 ETO16111.1 - 7.7e-37 125.6 0.0 1.1e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 ETO16111.1 - 0.00054 19.8 0.0 0.01 15.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETO16112.1 - 2.7e-21 75.7 0.4 6.3e-21 74.5 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETO16112.1 - 4.9e-15 55.9 4.3 1.9e-10 40.9 0.6 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETO16112.1 - 4.3e-07 30.2 1.5 0.03 14.4 0.0 2.4 1 1 2 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETO16112.1 - 6.6e-07 28.5 0.3 0.0036 16.2 0.0 2.0 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 ETO16112.1 - 0.00095 17.7 5.1 0.71 8.2 0.1 3.0 2 1 1 3 3 3 2 HI0933-like protein 3HCDH_N PF02737.13 ETO16112.1 - 0.0018 17.9 0.5 0.0049 16.5 0.1 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.19 ETO16112.1 - 0.0019 17.1 5.8 1.3 7.8 0.6 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 ETO16112.1 - 0.0074 15.8 0.1 0.01 15.3 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 ETO16112.1 - 0.032 13.2 2.2 0.16 10.9 0.3 2.3 3 0 0 3 3 3 0 FAD binding domain Mqo PF06039.10 ETO16112.1 - 0.067 11.3 3.7 0.44 8.6 0.1 2.3 2 1 1 3 3 3 0 Malate:quinone oxidoreductase (Mqo) NAD_binding_8 PF13450.1 ETO16112.1 - 0.067 13.2 0.5 0.53 10.3 0.2 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.9 ETO16112.1 - 0.068 12.5 0.5 0.16 11.2 0.2 1.8 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain XdhC_C PF13478.1 ETO16112.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.6 2 0 0 2 2 2 0 XdhC Rossmann domain Myosin_N PF02736.14 ETO16112.1 - 0.24 11.1 2.0 0.5 10.0 0.6 2.1 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain GIDA PF01134.17 ETO16112.1 - 0.36 9.6 2.7 4.7 5.9 0.2 2.4 2 1 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 ETO16112.1 - 0.51 9.1 5.0 2.6 6.7 0.1 2.7 2 1 1 3 3 3 0 FAD binding domain ArfGap PF01412.13 ETO16114.1 - 1.6e-34 118.2 2.0 2.3e-33 114.4 1.4 2.5 1 1 0 1 1 1 1 Putative GTPase activating protein for Arf tRNA_synt_1c_R1 PF04558.10 ETO16114.1 - 0.028 13.9 0.0 0.051 13.0 0.0 1.4 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 TPR_11 PF13414.1 ETO16115.1 - 3.4e-31 106.6 21.4 3.8e-12 45.6 0.2 4.2 3 1 0 4 4 4 4 TPR repeat TPR_2 PF07719.12 ETO16115.1 - 9.7e-25 84.4 18.1 5.2e-06 25.9 0.3 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 ETO16115.1 - 3e-24 83.1 12.0 2.8e-07 30.1 0.1 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETO16115.1 - 1.1e-23 81.7 23.9 9e-06 25.0 3.4 7.2 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO16115.1 - 4.2e-16 57.9 0.0 0.026 15.1 0.0 6.3 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 ETO16115.1 - 3e-15 54.7 21.8 8.8e-05 22.0 0.5 6.2 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 ETO16115.1 - 1.5e-14 53.6 22.3 2.9e-08 33.5 3.3 5.4 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO16115.1 - 8.1e-12 45.4 0.1 0.0042 17.7 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO16115.1 - 1.5e-10 41.2 1.0 0.00012 22.2 0.0 4.5 2 2 3 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO16115.1 - 4.5e-10 38.5 1.2 0.0026 17.4 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETO16115.1 - 2.4e-05 24.0 7.5 0.12 12.3 0.2 5.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETO16115.1 - 0.00055 19.7 0.4 3.3 7.6 0.0 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO16115.1 - 0.0068 16.8 8.6 11 6.7 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO16115.1 - 0.011 15.6 3.7 97 2.9 0.0 5.3 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPPII_N PF12583.3 ETO16115.1 - 0.028 14.5 3.9 2.6 8.2 0.0 3.1 3 0 0 3 3 3 0 Tripeptidyl peptidase II N terminal TPR_20 PF14561.1 ETO16115.1 - 0.03 14.4 0.5 2.9 8.0 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 ETO16115.1 - 1.1 9.1 4.3 18 5.3 0.0 3.4 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Mlo PF03094.10 ETO16116.1 - 0.026 12.6 0.8 0.032 12.3 0.5 1.1 1 0 0 1 1 1 0 Mlo family DUF4618 PF15397.1 ETO16118.1 - 0.005 16.2 1.1 0.0075 15.6 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) DUF2161 PF09929.4 ETO16119.1 - 1.4 8.8 6.8 0.34 10.8 2.3 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2161) RCC1 PF00415.13 ETO16120.1 - 4.5e-32 110.0 23.0 7.6e-14 51.6 0.0 6.7 6 2 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO16120.1 - 1.7e-22 78.4 24.3 2.1e-07 30.3 1.1 6.5 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Menin PF05053.8 ETO16120.1 - 0.013 13.6 0.5 0.016 13.4 0.4 1.1 1 0 0 1 1 1 0 Menin DUF3300 PF11737.3 ETO16120.1 - 0.75 9.0 4.0 1.6 7.9 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3300) Secretin_N_2 PF07655.8 ETO16120.1 - 1.6 9.1 18.6 4 7.8 12.9 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain Vfa1 PF08432.5 ETO16121.1 - 0.0015 18.5 11.0 0.002 18.2 7.6 1.1 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DUF2722 PF10846.3 ETO16121.1 - 0.0042 16.1 4.1 0.0051 15.8 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) BUD22 PF09073.5 ETO16121.1 - 0.0045 16.1 13.6 0.0054 15.8 9.4 1.1 1 0 0 1 1 1 1 BUD22 TMEMspv1-c74-12 PF11044.3 ETO16121.1 - 0.0075 15.7 1.0 0.013 15.0 0.7 1.4 1 0 0 1 1 1 1 Plectrovirus spv1-c74 ORF 12 transmembrane protein Tom37_C PF11801.3 ETO16121.1 - 0.01 15.7 3.0 0.014 15.2 2.0 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain Daxx PF03344.10 ETO16121.1 - 0.049 12.1 24.1 0.061 11.8 16.7 1.0 1 0 0 1 1 1 0 Daxx Family GEMIN8 PF15348.1 ETO16121.1 - 0.12 12.4 8.2 0.16 12.0 5.7 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Zip PF02535.17 ETO16121.1 - 0.16 10.9 1.1 0.16 10.9 0.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DDHD PF02862.12 ETO16121.1 - 0.22 11.2 2.7 0.29 10.8 1.9 1.2 1 0 0 1 1 1 0 DDHD domain PPP4R2 PF09184.6 ETO16121.1 - 0.22 11.0 20.3 0.25 10.8 14.1 1.2 1 0 0 1 1 1 0 PPP4R2 NPR3 PF03666.8 ETO16121.1 - 0.23 9.9 5.7 0.27 9.6 3.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 VID27 PF08553.5 ETO16121.1 - 0.24 9.5 13.5 0.24 9.5 9.4 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein TFIIA PF03153.8 ETO16121.1 - 0.28 11.0 16.1 0.35 10.7 11.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3c_N PF05470.7 ETO16121.1 - 0.33 9.0 8.9 0.36 8.8 6.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Poxvirus_B22R PF04395.7 ETO16121.1 - 0.35 10.3 3.9 0.4 10.1 2.7 1.0 1 0 0 1 1 1 0 Poxvirus B22R protein DUF2457 PF10446.4 ETO16121.1 - 0.41 9.3 23.6 0.51 8.9 16.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NAP PF00956.13 ETO16121.1 - 0.42 9.6 12.8 0.69 8.9 8.9 1.4 1 1 0 1 1 1 0 Nucleosome assembly protein (NAP) AAA_23 PF13476.1 ETO16121.1 - 0.71 10.1 10.1 0.83 9.9 7.0 1.1 1 0 0 1 1 1 0 AAA domain Trypan_PARP PF05887.6 ETO16121.1 - 0.71 9.6 13.6 0.77 9.5 9.4 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ycf1 PF05758.7 ETO16121.1 - 0.8 7.3 5.7 0.95 7.0 4.0 1.1 1 0 0 1 1 1 0 Ycf1 PTRF_SDPR PF15237.1 ETO16121.1 - 0.84 8.9 8.6 1.1 8.6 5.9 1.1 1 0 0 1 1 1 0 PTRF/SDPR family CobT PF06213.7 ETO16121.1 - 1.7 7.6 19.8 1.8 7.6 13.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Rhabdo_ncap PF00945.13 ETO16121.1 - 3.1 6.2 6.7 3.6 6.0 4.7 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Cwf_Cwc_15 PF04889.7 ETO16121.1 - 4.4 6.9 23.4 5.7 6.5 16.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ank_2 PF12796.2 ETO16122.1 - 0.058 13.7 0.0 0.082 13.2 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) WD40 PF00400.27 ETO16124.1 - 2.9e-33 112.5 2.5 2.2e-13 49.5 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO16124.1 - 3.1e-06 25.6 0.1 0.0035 15.5 0.0 2.9 1 1 0 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO16124.1 - 5.1e-05 23.0 0.0 0.02 14.5 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 ETO16124.1 - 0.011 14.4 0.3 0.074 11.7 0.1 2.2 1 1 1 2 2 2 0 Nup133 N terminal like zf-4CXXC_R1 PF10497.4 ETO16125.1 - 2.2e-08 34.1 15.7 5.4e-08 32.9 10.9 1.6 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 ASC PF00858.19 ETO16126.1 - 0.44 9.1 4.9 0.5 8.9 3.4 1.0 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel Atg14 PF10186.4 ETO16126.1 - 0.6 9.0 5.7 0.63 8.9 3.9 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 RabGAP-TBC PF00566.13 ETO16126.1 - 1.5 8.1 4.8 1.9 7.9 3.3 1.0 1 0 0 1 1 1 0 Rab-GTPase-TBC domain ParB PF08775.5 ETO16126.1 - 2.1 8.6 17.1 2.8 8.2 11.9 1.1 1 0 0 1 1 1 0 ParB family Mannitol_dh PF01232.18 ETO16128.1 - 0.0078 16.1 0.0 0.025 14.5 0.0 1.8 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain CHD5 PF04420.9 ETO16128.1 - 0.013 15.1 0.0 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 CHD5-like protein CUE PF02845.11 ETO16128.1 - 0.1 12.0 0.2 0.22 11.0 0.1 1.5 1 0 0 1 1 1 0 CUE domain Acyl_transf_3 PF01757.17 ETO16129.1 - 0.006 15.4 0.8 0.01 14.6 0.6 1.3 1 0 0 1 1 1 1 Acyltransferase family WD40 PF00400.27 ETO16130.1 - 1.4e-33 113.5 6.0 7.1e-11 41.5 0.0 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO16130.1 - 3.1e-06 25.6 0.8 0.096 10.7 0.1 2.8 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO16130.1 - 0.0081 14.9 2.9 0.64 8.7 0.2 2.5 1 1 2 3 3 3 2 Nup133 N terminal like DUF1258 PF06869.7 ETO16130.1 - 0.027 13.5 0.5 4.7 6.2 0.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1258) USP7_ICP0_bdg PF12436.3 ETO16130.1 - 0.054 12.7 0.0 0.076 12.2 0.0 1.3 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 PD40 PF07676.7 ETO16130.1 - 0.17 11.6 0.4 13 5.6 0.0 2.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat She9_MDM33 PF05546.6 ETO16131.1 - 0.072 12.6 0.7 0.099 12.1 0.5 1.2 1 0 0 1 1 1 0 She9 / Mdm33 family WBP-1 PF11669.3 ETO16131.1 - 1.5 8.9 4.5 0.99 9.5 0.1 2.2 1 1 1 2 2 2 0 WW domain-binding protein 1 TPR_5 PF12688.2 ETO16132.1 - 0.09 12.8 0.2 0.28 11.2 0.1 1.8 1 0 0 1 1 1 0 Tetratrico peptide repeat Thioredoxin_2 PF13098.1 ETO16134.1 - 0.025 14.7 0.6 0.025 14.7 0.4 2.1 1 1 1 2 2 2 0 Thioredoxin-like domain DOR PF14839.1 ETO16134.1 - 0.14 11.9 7.5 0.18 11.5 5.2 1.1 1 0 0 1 1 1 0 DOR family DRY_EERY PF09750.4 ETO16134.1 - 0.77 9.8 3.7 2.1 8.4 0.1 2.1 2 0 0 2 2 2 0 Alternative splicing regulator Collagen PF01391.13 ETO16135.1 - 1.5e-05 24.4 33.4 1.5e-05 24.4 23.1 2.3 1 1 1 2 2 2 1 Collagen triple helix repeat (20 copies) UCH PF00443.24 ETO16136.1 - 7.5e-40 136.7 3.6 7.5e-40 136.7 2.5 2.8 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO16136.1 - 2.1e-24 86.5 3.5 2.1e-24 86.5 2.4 2.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase EF-hand_6 PF13405.1 ETO16136.1 - 0.0032 17.2 0.1 0.045 13.6 0.0 3.1 2 0 0 2 2 2 1 EF-hand domain TMEMspv1-c74-12 PF11044.3 ETO16136.1 - 7.4 6.2 9.4 23 4.6 6.5 1.9 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Daxx PF03344.10 ETO16137.1 - 1.4 7.3 16.0 1.5 7.2 11.1 1.0 1 0 0 1 1 1 0 Daxx Family cNMP_binding PF00027.24 ETO16138.1 - 3e-21 75.0 0.0 4.3e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF2603 PF10788.4 ETO16139.1 - 0.019 14.7 0.6 0.041 13.6 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2603) 2_5_RNA_ligase2 PF13563.1 ETO16139.1 - 0.029 14.0 0.0 0.056 13.1 0.0 1.5 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily VPS9 PF02204.13 ETO16140.1 - 6.8e-09 35.6 0.0 1.9e-08 34.2 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ribosomal_60s PF00428.14 ETO16140.1 - 0.025 14.9 0.6 0.061 13.7 0.4 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein TPR_2 PF07719.12 ETO16140.1 - 0.27 11.2 2.5 4.3 7.4 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat MbeD_MobD PF04899.7 ETO16140.1 - 0.7 9.8 6.4 0.27 11.1 0.6 2.9 3 0 0 3 3 3 0 MbeD/MobD like LRAT PF04970.8 ETO16141.1 - 5.7e-11 42.4 0.7 5.7e-11 42.4 0.5 1.8 2 0 0 2 2 2 1 Lecithin retinol acyltransferase Serinc PF03348.10 ETO16142.1 - 0.0092 14.7 1.3 0.0092 14.7 0.9 2.0 1 1 1 2 2 2 1 Serine incorporator (Serinc) DUF106 PF01956.11 ETO16142.1 - 0.021 14.3 0.1 0.021 14.3 0.1 2.6 3 0 0 3 3 3 0 Integral membrane protein DUF106 7tm_1 PF00001.16 ETO16142.1 - 0.19 10.8 5.8 0.19 10.8 3.0 1.7 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) AgrB PF04647.10 ETO16142.1 - 0.27 10.2 4.1 0.53 9.3 0.1 2.5 2 0 0 2 2 2 0 Accessory gene regulator B ESSS PF10183.4 ETO16142.1 - 0.47 10.8 3.6 0.66 10.4 0.1 2.8 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) CENP-B_dimeris PF09026.5 ETO16142.1 - 0.53 10.5 8.3 24 5.2 4.3 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF912 PF06024.7 ETO16142.1 - 0.6 10.1 0.0 0.6 10.1 0.0 3.1 3 1 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Nucleoside_tran PF01733.13 ETO16142.1 - 0.74 8.9 6.8 0.16 11.0 1.8 1.9 1 1 1 2 2 2 0 Nucleoside transporter PBP1_TM PF14812.1 ETO16142.1 - 2.2 8.6 35.4 6.1 7.2 14.6 3.4 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1510 PF07423.6 ETO16142.1 - 4.7 6.5 32.2 0.014 14.7 6.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) ENTH PF01417.15 ETO16143.1 - 2.4e-32 111.4 0.0 2.9e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 ETO16143.1 - 1.3e-08 33.8 0.0 1.6e-08 33.6 0.0 1.0 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 ETO16143.1 - 0.012 15.2 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 VHS domain WEMBL PF05701.6 ETO16144.1 - 0.021 13.3 3.4 0.027 12.9 2.4 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Folliculin PF11704.3 ETO16144.1 - 0.026 14.1 0.7 0.033 13.7 0.5 1.4 1 1 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport LolB PF03550.9 ETO16144.1 - 0.067 12.7 0.1 0.31 10.5 0.0 1.9 2 0 0 2 2 2 0 Outer membrane lipoprotein LolB Bacillus_HBL PF05791.6 ETO16144.1 - 0.088 12.1 1.4 0.14 11.5 0.6 1.6 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) CENP-Q PF13094.1 ETO16144.1 - 0.53 10.2 5.8 8.8 6.3 4.0 2.0 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 ETO16144.1 - 1.1 8.7 6.3 0.1 12.1 0.4 1.9 2 1 0 2 2 2 0 IncA protein Sec2p PF06428.6 ETO16144.1 - 7.1 6.5 8.0 0.82 9.5 1.3 2.3 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p Nop14 PF04147.7 ETO16145.1 - 0.026 12.4 15.1 0.033 12.1 10.5 1.1 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.9 ETO16145.1 - 0.043 13.3 10.1 0.075 12.5 7.0 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.9 ETO16145.1 - 0.23 9.4 11.5 0.34 8.8 8.0 1.2 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.6 ETO16145.1 - 0.45 8.5 9.3 0.64 8.0 6.4 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF912 PF06024.7 ETO16145.1 - 2 8.5 0.0 2 8.5 0.0 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Daxx PF03344.10 ETO16145.1 - 2.8 6.3 16.9 4.3 5.7 11.7 1.2 1 0 0 1 1 1 0 Daxx Family FAM176 PF14851.1 ETO16145.1 - 3.7 7.2 11.3 0.58 9.8 4.7 2.0 2 0 0 2 2 2 0 FAM176 family Sporozoite_P67 PF05642.6 ETO16145.1 - 3.8 5.2 12.1 6.1 4.5 8.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2457 PF10446.4 ETO16145.1 - 5.9 5.5 30.0 11 4.6 20.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF4424 PF14415.1 ETO16146.1 - 0.00063 19.3 1.1 0.00095 18.7 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4424) FPL PF09758.4 ETO16146.1 - 0.01 15.6 2.2 0.2 11.4 0.3 2.3 2 0 0 2 2 2 0 Uncharacterised conserved protein SR-25 PF10500.4 ETO16146.1 - 0.92 8.9 5.5 3 7.2 0.4 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Anoctamin PF04547.7 ETO16147.1 - 7.5e-44 150.1 21.6 9.4e-44 149.7 15.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel HSP90 PF00183.13 ETO16149.1 - 1.8e-64 218.0 32.6 5.3e-37 127.4 6.0 3.0 2 1 1 3 3 3 3 Hsp90 protein DUF4366 PF14283.1 ETO16149.1 - 0.029 13.7 0.8 0.029 13.7 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) RST PF12174.3 ETO16149.1 - 0.064 13.0 0.5 0.19 11.5 0.3 1.8 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain NusB PF01029.13 ETO16149.1 - 5.6 6.9 11.1 8.3 6.4 0.1 3.4 2 1 1 3 3 3 0 NusB family DDDD PF10161.4 ETO16151.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative mitochondrial precursor protein HSP90 PF00183.13 ETO16152.1 - 1.1e-39 136.2 3.8 1.3e-39 136.0 2.7 1.0 1 0 0 1 1 1 1 Hsp90 protein Dynamin_N PF00350.18 ETO16154.1 - 8.7 6.1 11.6 0.28 11.0 0.6 3.1 3 0 0 3 3 3 0 Dynamin family AAA PF00004.24 ETO16155.1 - 4.9e-07 30.0 0.2 1.2e-06 28.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETO16155.1 - 0.003 17.5 0.0 0.064 13.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 ETO16155.1 - 0.0046 16.6 0.0 0.0097 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 ETO16155.1 - 0.0055 17.5 0.0 0.012 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 ETO16155.1 - 0.007 15.3 0.0 0.021 13.7 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.17 ETO16155.1 - 0.0081 16.3 0.0 0.034 14.3 0.0 1.9 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.16 ETO16155.1 - 0.01 15.0 0.1 0.018 14.1 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 ETO16155.1 - 0.014 15.5 0.0 0.035 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 ETO16155.1 - 0.019 14.8 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 ETO16155.1 - 0.02 13.9 0.0 0.038 13.0 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 ETO16155.1 - 0.055 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 ETO16155.1 - 0.064 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 ETO16155.1 - 0.09 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 ETO16155.1 - 0.1 11.9 0.5 0.32 10.4 0.0 1.9 3 0 0 3 3 3 0 IstB-like ATP binding protein Parvo_NS1 PF01057.12 ETO16155.1 - 0.15 10.9 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 BSP_II PF05432.6 ETO16157.1 - 0.16 11.2 2.6 0.22 10.7 1.8 1.0 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Pkinase PF00069.20 ETO16158.1 - 1.7e-05 24.0 0.2 2.5e-05 23.5 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain BLVR PF06375.6 ETO16158.1 - 4 7.2 6.0 6.5 6.5 4.2 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Gemini_V1 PF01524.12 ETO16159.1 - 0.1 12.5 0.1 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Geminivirus V1 protein WD40 PF00400.27 ETO16160.1 - 4.5e-14 51.6 0.7 6.5e-09 35.3 0.0 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat SGS PF05002.10 ETO16161.1 - 1.9 8.3 5.7 0.24 11.1 0.2 2.3 3 0 0 3 3 3 0 SGS domain Pkinase PF00069.20 ETO16162.1 - 3e-23 82.2 0.0 3.6e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO16162.1 - 7.6e-11 41.5 0.0 9.6e-11 41.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 ETO16163.1 - 8.2e-08 31.7 0.0 1.1e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.24 ETO16164.1 - 4.7e-20 71.1 0.0 6.5e-20 70.7 0.0 1.2 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Mcp5_PH PF12814.2 ETO16165.1 - 0.11 12.4 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology DUF547 PF04784.9 ETO16166.1 - 0.0024 17.7 0.2 0.0052 16.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF547 LRR_6 PF13516.1 ETO16167.1 - 3.8e-25 85.0 9.3 0.021 14.8 0.0 8.3 8 0 0 8 8 8 6 Leucine Rich repeat LRR_1 PF00560.28 ETO16167.1 - 6e-08 31.6 7.2 3.2 8.1 0.0 7.1 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_4 PF12799.2 ETO16167.1 - 4.5e-07 29.3 9.0 0.03 13.9 0.0 5.0 4 2 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO16167.1 - 2.7e-05 23.8 8.4 0.086 12.6 0.6 5.0 3 1 2 5 5 5 2 Leucine rich repeat LRR_7 PF13504.1 ETO16167.1 - 3.6e-05 23.2 12.0 5.4 7.6 0.0 7.7 8 0 0 8 8 8 1 Leucine rich repeat CDC45 PF02724.9 ETO16167.1 - 5.1 5.0 11.3 6.3 4.7 7.8 1.2 1 0 0 1 1 1 0 CDC45-like protein AAA PF00004.24 ETO16168.1 - 2.1e-41 141.2 0.0 4.5e-41 140.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETO16168.1 - 1.9e-05 24.3 0.0 7.7e-05 22.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 ETO16168.1 - 6.6e-05 23.7 1.2 0.00063 20.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 ETO16168.1 - 0.00011 21.3 0.0 0.00028 20.0 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 ETO16168.1 - 0.00018 21.6 0.4 0.074 13.2 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETO16168.1 - 0.00027 20.9 0.1 0.043 13.8 0.1 2.9 1 1 2 3 3 3 1 AAA ATPase domain TIP49 PF06068.8 ETO16168.1 - 0.0016 17.2 0.0 0.0029 16.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 ETO16168.1 - 0.0016 17.8 1.4 0.099 12.0 0.3 2.3 1 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 ETO16168.1 - 0.0018 18.1 0.0 0.011 15.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 ETO16168.1 - 0.0023 17.3 0.0 0.0049 16.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 ETO16168.1 - 0.0024 16.9 0.0 0.0052 15.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 ETO16168.1 - 0.0029 17.0 0.1 0.081 12.4 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.1 ETO16168.1 - 0.0033 17.1 0.2 0.0073 16.0 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 ETO16168.1 - 0.017 15.0 0.2 0.052 13.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 ETO16168.1 - 0.018 14.2 0.3 0.038 13.1 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 ETO16168.1 - 0.028 14.2 0.0 0.092 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 ETO16168.1 - 0.03 14.6 7.3 0.034 14.4 0.0 3.3 3 1 0 3 3 3 0 AAA domain AAA_28 PF13521.1 ETO16168.1 - 0.031 14.2 0.0 0.074 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 ETO16168.1 - 0.058 13.4 0.0 0.19 11.7 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 ETO16168.1 - 0.069 12.2 0.1 0.26 10.3 0.0 1.9 2 0 0 2 2 2 0 KaiC Paramyxo_ncap PF00973.14 ETO16168.1 - 3.7 6.1 9.7 6.6 5.3 6.7 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein HEAT PF02985.17 ETO16169.1 - 0.00064 19.5 5.2 0.77 10.0 0.0 4.9 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.1 ETO16169.1 - 0.011 15.9 0.5 3.3 8.0 0.2 3.2 2 1 0 2 2 2 0 HEAT repeats Secretin_N_2 PF07655.8 ETO16169.1 - 0.19 12.1 11.5 0.04 14.3 5.3 1.9 2 0 0 2 2 2 0 Secretin N-terminal domain Methyltransf_12 PF08242.7 ETO16169.1 - 0.88 10.0 5.7 4.6 7.7 1.7 3.0 3 0 0 3 3 3 0 Methyltransferase domain DUF912 PF06024.7 ETO16169.1 - 2.4 8.2 8.2 8.4 6.5 5.7 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) HEAT_EZ PF13513.1 ETO16170.1 - 1.6e-05 25.2 1.1 0.011 16.1 0.1 3.6 3 0 0 3 3 3 1 HEAT-like repeat HEAT_2 PF13646.1 ETO16170.1 - 0.00034 20.8 0.7 0.38 11.0 0.0 3.2 3 0 0 3 3 3 2 HEAT repeats DUF3349 PF11829.3 ETO16170.1 - 0.063 13.7 0.1 7.8 7.0 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3349) Vac14_Fab1_bd PF12755.2 ETO16170.1 - 0.081 13.3 2.5 1.1 9.7 0.0 3.6 2 2 2 4 4 4 0 Vacuolar 14 Fab1-binding region SUR7 PF06687.7 ETO16170.1 - 0.16 11.5 4.0 0.086 12.3 0.5 2.1 2 0 0 2 2 2 0 SUR7/PalI family HEAT PF02985.17 ETO16170.1 - 0.28 11.3 10.2 3.7 7.8 0.1 5.4 5 0 0 5 5 5 0 HEAT repeat Ribosomal_60s PF00428.14 ETO16170.1 - 0.51 10.7 3.9 1.2 9.5 2.7 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Endotoxin_C PF03944.9 ETO16170.1 - 3.2 7.8 8.5 20 5.2 6.0 2.0 1 1 0 1 1 1 0 delta endotoxin DUF3682 PF12446.3 ETO16170.1 - 5.5 7.2 7.1 11 6.3 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DUF3169 PF11368.3 ETO16170.1 - 7.8 5.6 6.6 0.82 8.8 0.4 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) Spore_YhcN_YlaJ PF09580.5 ETO16170.1 - 9 6.3 12.8 1.7 8.6 5.1 2.1 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) WD40 PF00400.27 ETO16171.1 - 2.2e-78 255.6 16.5 1.6e-11 43.5 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO16171.1 - 8.2e-08 30.8 3.4 0.33 9.0 0.0 5.1 1 1 2 4 4 4 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO16171.1 - 4.1e-05 23.1 0.3 0.00077 18.9 0.2 2.5 1 1 0 1 1 1 1 PQQ-like domain Resistin PF06954.6 ETO16171.1 - 0.00016 21.8 1.3 13 6.1 0.0 4.7 2 1 3 5 5 5 1 Resistin Cytochrom_D1 PF02239.11 ETO16171.1 - 0.0025 16.1 0.8 1.3 7.2 0.0 2.8 1 1 2 3 3 3 3 Cytochrome D1 heme domain PD40 PF07676.7 ETO16171.1 - 0.064 12.9 4.7 8.6 6.1 0.1 3.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Gmad1 PF10647.4 ETO16171.1 - 0.065 12.6 0.1 0.37 10.1 0.0 2.2 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain NADH_B2 PF14813.1 ETO16171.1 - 0.12 12.0 0.6 0.27 10.9 0.5 1.5 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 G-alpha PF00503.15 ETO16172.1 - 4.9e-18 64.9 0.3 5.6e-18 64.7 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO16172.1 - 0.0025 17.0 0.0 0.0028 16.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Tap-RNA_bind PF09162.5 ETO16172.1 - 0.039 13.5 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 Tap, RNA-binding G-alpha PF00503.15 ETO16173.1 - 4.7e-22 78.2 2.7 6.2e-22 77.8 1.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit AAA_33 PF13671.1 ETO16173.1 - 0.00094 19.0 0.1 0.007 16.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 ETO16173.1 - 0.0021 18.3 0.8 0.0031 17.7 0.6 1.5 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 ETO16173.1 - 0.0028 17.1 0.2 0.0045 16.4 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 ETO16173.1 - 0.0031 17.8 1.3 0.035 14.4 0.9 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO16173.1 - 0.0062 17.3 0.0 0.012 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain Arf PF00025.16 ETO16173.1 - 0.016 14.4 0.0 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Z1 PF10593.4 ETO16173.1 - 0.023 13.9 0.4 0.03 13.5 0.2 1.1 1 0 0 1 1 1 0 Z1 domain MMR_HSR1 PF01926.18 ETO16173.1 - 0.047 13.6 0.1 0.075 12.9 0.1 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase Mg_chelatase PF01078.16 ETO16173.1 - 0.049 12.7 0.0 0.099 11.7 0.0 1.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 ETO16173.1 - 0.054 13.4 0.0 0.076 12.9 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 ETO16173.1 - 0.071 12.2 0.3 0.1 11.8 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF258 PRK PF00485.13 ETO16173.1 - 0.091 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family WD40 PF00400.27 ETO16174.1 - 4e-31 105.7 9.3 3e-10 39.5 1.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO16174.1 - 1.6e-05 23.2 0.7 0.008 14.3 0.1 2.8 2 1 0 2 2 2 2 Nucleoporin Nup120/160 SurA_N_3 PF13624.1 ETO16175.1 - 0.036 14.0 0.0 0.036 14.0 0.0 1.0 1 0 0 1 1 1 0 SurA N-terminal domain DUF3536 PF12055.3 ETO16176.1 - 0.08 12.1 0.3 0.096 11.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3536) Chalcone PF02431.10 ETO16176.1 - 0.17 11.2 7.9 5 6.4 3.5 2.0 1 1 1 2 2 2 0 Chalcone-flavanone isomerase PLRV_ORF5 PF01690.12 ETO16176.1 - 0.48 9.5 4.7 0.53 9.3 3.2 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein FAM176 PF14851.1 ETO16176.1 - 1.8 8.2 6.7 2.3 7.8 4.7 1.2 1 0 0 1 1 1 0 FAM176 family DUF3414 PF11894.3 ETO16179.1 - 3e-19 67.6 0.0 3.4e-19 67.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) NST1 PF13945.1 ETO16180.1 - 0.062 13.3 12.9 0.08 13.0 8.9 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Period_C PF12114.3 ETO16180.1 - 0.25 10.9 6.1 0.28 10.7 4.2 1.0 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Menin PF05053.8 ETO16180.1 - 6.7 4.7 10.6 6.8 4.7 7.3 1.0 1 0 0 1 1 1 0 Menin ABC_membrane PF00664.18 ETO16183.1 - 0.13 11.5 0.0 0.44 9.9 0.0 1.7 1 1 1 2 2 2 0 ABC transporter transmembrane region PFEMP PF03011.10 ETO16183.1 - 0.2 12.0 3.6 0.27 11.5 2.5 1.1 1 0 0 1 1 1 0 PFEMP DBL domain Cbl_N PF02262.11 ETO16183.1 - 1.2 8.8 5.8 2.2 8.0 1.2 2.2 2 0 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 MSP1_C PF07462.6 ETO16184.1 - 0.066 11.6 2.6 0.11 10.8 1.8 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus AIRC PF00731.15 ETO16184.1 - 0.071 12.3 1.9 0.16 11.2 1.3 1.5 1 0 0 1 1 1 0 AIR carboxylase Tir_receptor_C PF07489.6 ETO16184.1 - 1.2 8.8 12.6 0.23 11.1 5.5 2.1 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus SSP160 PF06933.6 ETO16184.1 - 1.3 6.9 17.1 2.9 5.7 11.9 1.5 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Adeno_PIX PF03955.9 ETO16184.1 - 6.6 7.3 10.5 1.3 9.5 4.4 2.0 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) LMBR1 PF04791.11 ETO16185.1 - 0.0038 15.8 1.0 0.0038 15.8 0.7 1.5 1 1 0 1 1 1 1 LMBR1-like membrane protein UAA PF08449.6 ETO16185.1 - 0.0092 14.9 1.1 0.014 14.3 0.8 1.3 1 0 0 1 1 1 1 UAA transporter family DUF4018 PF13210.1 ETO16185.1 - 0.024 14.0 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4018) Ctr PF04145.10 ETO16185.1 - 0.049 13.6 0.5 0.71 9.9 0.0 2.1 2 0 0 2 2 2 0 Ctr copper transporter family YMF19 PF02326.10 ETO16185.1 - 0.055 14.0 1.6 0.055 14.0 1.1 2.5 2 1 0 2 2 2 0 Plant ATP synthase F0 Hep_59 PF07052.6 ETO16185.1 - 4.7 7.6 18.5 0.72 10.2 5.1 2.3 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 PBP1_TM PF14812.1 ETO16185.1 - 5.1 7.4 19.4 0.26 11.6 3.6 3.2 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Bap31 PF05529.7 ETO16185.1 - 5.9 6.2 8.3 0.45 9.9 0.2 2.2 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like UAA PF08449.6 ETO16186.1 - 2e-29 102.4 11.5 2.2e-29 102.3 8.0 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 ETO16186.1 - 0.0002 21.3 13.9 0.0012 18.9 5.8 2.3 2 1 1 3 3 3 2 EamA-like transporter family TPT PF03151.11 ETO16186.1 - 0.0012 18.5 15.8 0.0031 17.1 6.5 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family DUF981 PF06168.6 ETO16186.1 - 0.018 14.7 0.4 0.029 14.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF981) CD47 PF04549.9 ETO16186.1 - 0.021 14.7 4.1 0.07 13.1 0.3 2.5 1 1 0 2 2 2 0 CD47 transmembrane region DUF4231 PF14015.1 ETO16186.1 - 0.25 11.3 1.7 1.7 8.6 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) FAIM1 PF06905.8 ETO16187.1 - 0.0041 16.3 0.4 0.0056 15.8 0.2 1.3 1 1 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) Cadherin-like PF12733.2 ETO16187.1 - 0.07 13.4 0.5 0.084 13.1 0.2 1.3 1 1 0 1 1 1 0 Cadherin-like beta sandwich domain PRA-CH PF01502.13 ETO16187.1 - 0.12 11.9 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl-AMP cyclohydrolase DinB_2 PF12867.2 ETO16188.1 - 0.019 15.2 0.4 0.14 12.5 0.3 2.5 1 1 0 1 1 1 0 DinB superfamily Myosin_tail_1 PF01576.14 ETO16188.1 - 0.059 11.1 44.9 0.022 12.5 24.9 2.2 1 1 1 2 2 2 0 Myosin tail CENP-F_leu_zip PF10473.4 ETO16188.1 - 0.2 11.5 48.2 0.48 10.2 13.5 5.0 1 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 ETO16188.1 - 0.58 9.5 45.2 3.4 7.0 24.6 3.5 1 1 1 2 2 2 0 Intermediate filament protein TMF_TATA_bd PF12325.3 ETO16188.1 - 1 9.0 41.2 0.39 10.4 5.8 4.7 2 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding NADPH_Ox PF08414.5 ETO16190.1 - 0.12 12.4 1.8 0.62 10.1 0.1 2.7 2 1 1 3 3 3 0 Respiratory burst NADPH oxidase RimK PF08443.6 ETO16191.1 - 1e-30 106.6 0.5 3.7e-27 95.0 0.1 3.2 1 1 1 2 2 2 2 RimK-like ATP-grasp domain GSH-S_ATP PF02955.11 ETO16191.1 - 5e-08 32.2 0.0 1.1e-07 31.2 0.0 1.6 1 1 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_4 PF13535.1 ETO16191.1 - 0.00011 22.0 0.0 0.062 13.0 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 ETO16191.1 - 0.012 14.3 0.4 0.061 12.0 0.1 2.1 1 1 1 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 ETO16191.1 - 0.024 14.5 0.2 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain ATP-synt_E PF05680.7 ETO16191.1 - 3.3 7.7 6.7 0.57 10.1 0.2 2.6 3 0 0 3 3 3 0 ATP synthase E chain DUF1217 PF06748.7 ETO16192.1 - 0.046 13.8 0.3 0.089 12.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1217) DUF4131 PF13567.1 ETO16194.1 - 0.5 9.7 4.3 0.81 9.0 3.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) SAM_1 PF00536.25 ETO16196.1 - 0.021 14.9 0.8 2.7 8.2 0.0 3.5 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO16196.1 - 0.025 14.3 0.9 3 7.7 0.0 3.7 4 0 0 4 4 4 0 SAM domain (Sterile alpha motif) DUF4291 PF14124.1 ETO16196.1 - 0.075 12.6 1.6 0.14 11.7 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4291) Chalcone PF02431.10 ETO16196.1 - 0.11 11.8 11.6 1.8 7.9 3.7 3.0 2 1 1 3 3 3 0 Chalcone-flavanone isomerase CP12 PF02672.10 ETO16196.1 - 0.15 12.5 4.6 0.76 10.2 2.4 2.6 2 0 0 2 2 2 0 CP12 domain FAM176 PF14851.1 ETO16196.1 - 0.24 11.0 5.2 0.39 10.3 3.6 1.3 1 0 0 1 1 1 0 FAM176 family MttA_Hcf106 PF02416.11 ETO16196.1 - 2 7.6 6.6 9.1 5.4 2.4 2.5 2 1 0 2 2 2 0 mttA/Hcf106 family Lumazine_bd PF12870.2 ETO16196.1 - 4.6 7.3 15.1 0.54 10.3 6.5 2.4 2 2 1 3 3 3 0 Lumazine-binding domain Spc7 PF08317.6 ETO16197.1 - 0.0062 15.2 10.7 0.0082 14.8 7.4 1.2 1 1 0 1 1 1 1 Spc7 kinetochore protein Phage_GP20 PF06810.6 ETO16197.1 - 0.017 14.5 14.9 0.025 14.0 10.3 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Atg14 PF10186.4 ETO16197.1 - 0.069 12.0 7.7 0.082 11.8 5.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CASP_C PF08172.7 ETO16197.1 - 0.17 10.8 3.5 0.21 10.5 2.4 1.2 1 0 0 1 1 1 0 CASP C terminal Ribosomal_L25p PF01386.14 ETO16197.1 - 0.22 11.6 5.3 0.39 10.8 0.1 2.3 1 1 1 2 2 2 0 Ribosomal L25p family FlxA PF14282.1 ETO16197.1 - 0.56 10.1 14.3 1.2 9.1 9.9 1.7 1 0 0 1 1 1 0 FlxA-like protein IncA PF04156.9 ETO16197.1 - 1.5 8.4 7.0 1.7 8.2 4.8 1.2 1 0 0 1 1 1 0 IncA protein DUF724 PF05266.9 ETO16197.1 - 1.7 8.2 7.9 2.4 7.7 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF1664 PF07889.7 ETO16197.1 - 2.4 7.9 5.7 4.6 7.0 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Sec2p PF06428.6 ETO16197.1 - 2.7 7.8 10.3 0.77 9.6 5.0 1.7 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p RNA_pol_Rpb1_5 PF04998.12 ETO16197.1 - 4.1 6.5 6.6 4.4 6.4 4.6 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Exonuc_VII_L PF02601.10 ETO16197.1 - 4.8 6.2 9.5 5.1 6.2 6.6 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DivIC PF04977.10 ETO16197.1 - 9.9 5.7 9.4 25 4.4 6.5 1.8 1 1 0 1 1 1 0 Septum formation initiator zf-C3HC4_2 PF13923.1 ETO16201.1 - 7.6e-06 25.8 4.7 7.6e-06 25.8 3.2 4.4 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO16201.1 - 9.8e-06 25.1 7.8 9.8e-06 25.1 5.4 4.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO16201.1 - 2.6e-05 23.8 9.0 2.6e-05 23.8 6.2 4.3 2 2 1 3 3 3 1 zinc-RING finger domain IBR PF01485.16 ETO16201.1 - 4.5e-05 23.2 34.5 0.0091 15.8 0.2 3.6 3 1 0 3 3 3 2 IBR domain zf-RING_UBOX PF13445.1 ETO16201.1 - 0.00027 20.5 4.1 0.00027 20.5 2.8 2.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 ETO16201.1 - 0.00034 20.4 1.5 0.00034 20.4 1.1 4.4 4 1 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 ETO16201.1 - 0.0053 16.3 7.1 0.0053 16.3 4.9 4.2 2 2 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO16201.1 - 0.83 9.5 34.0 0.031 14.1 11.5 3.5 1 1 1 2 2 2 0 Ring finger domain Orthopox_A49R PF06489.6 ETO16202.1 - 0.27 11.2 4.8 1.3 9.0 1.3 2.8 1 1 2 3 3 3 0 Orthopoxvirus A49R protein DUF3596 PF12167.3 ETO16203.1 - 0.043 13.3 0.7 0.14 11.7 0.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3596) Thioredoxin_6 PF13848.1 ETO16204.1 - 5.5e-08 32.8 3.0 0.00093 19.0 0.3 3.7 3 1 0 3 3 3 2 Thioredoxin-like domain Utp12 PF04003.7 ETO16206.1 - 0.0075 16.1 1.9 0.023 14.6 0.0 2.5 3 0 0 3 3 3 1 Dip2/Utp12 Family CRAL_TRIO PF00650.15 ETO16207.1 - 0.061 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 CRAL/TRIO domain WD40 PF00400.27 ETO16208.1 - 3e-80 261.4 23.1 5.3e-13 48.3 0.3 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO16208.1 - 7e-14 51.9 0.3 2e-05 24.3 0.0 3.8 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO16208.1 - 1.6e-08 33.2 1.3 0.00099 17.4 0.1 3.2 2 1 0 2 2 2 2 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO16208.1 - 0.00011 21.3 3.7 1.2 8.1 0.0 4.4 1 1 3 5 5 5 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 ETO16208.1 - 0.0011 17.1 6.2 0.057 11.5 0.1 4.2 1 1 3 4 4 4 1 Nucleoporin Nup120/160 Resistin PF06954.6 ETO16208.1 - 0.0031 17.7 1.6 5.4 7.3 0.0 5.0 2 1 4 6 6 6 1 Resistin Proteasome_A_N PF10584.4 ETO16208.1 - 0.018 14.3 0.9 38 3.7 0.0 4.4 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature PD40 PF07676.7 ETO16208.1 - 0.022 14.3 8.1 9.5 6.0 0.0 5.5 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat zf-CCHC_4 PF14392.1 ETO16209.1 - 0.03 13.9 24.0 0.036 13.7 3.0 3.4 2 1 1 3 3 3 0 Zinc knuckle zf-CCHC PF00098.18 ETO16209.1 - 0.18 11.7 29.8 0.8 9.7 5.2 3.4 3 0 0 3 3 3 0 Zinc knuckle DUF1707 PF08044.6 ETO16210.1 - 0.0063 16.2 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1707) DUF2183 PF09949.4 ETO16210.1 - 0.094 12.6 0.8 0.49 10.3 0.3 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2183) DUF1510 PF07423.6 ETO16211.1 - 0.021 14.2 20.8 0.028 13.8 14.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CENP-T PF15511.1 ETO16211.1 - 0.056 12.6 15.6 0.071 12.3 10.8 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF572 PF04502.8 ETO16211.1 - 0.2 10.8 11.4 0.27 10.4 7.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2201_N PF13203.1 ETO16211.1 - 0.44 9.6 3.8 0.51 9.4 2.7 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Hid1 PF12722.2 ETO16211.1 - 1.5 6.3 8.0 1.7 6.2 5.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LRR_6 PF13516.1 ETO16212.1 - 0.012 15.6 8.8 8 6.8 0.1 4.4 5 0 0 5 5 5 0 Leucine Rich repeat LRR_4 PF12799.2 ETO16212.1 - 0.051 13.2 6.4 6.4 6.5 0.1 3.7 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO16212.1 - 0.11 12.2 1.9 12 5.7 0.1 2.9 3 0 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.28 ETO16212.1 - 0.26 11.4 2.9 38 4.8 0.1 3.8 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_7 PF13504.1 ETO16212.1 - 0.57 10.6 3.9 67 4.3 0.1 4.3 4 1 0 4 4 4 0 Leucine rich repeat Nucleoside_tran PF01733.13 ETO16214.1 - 0.047 12.8 0.7 0.054 12.6 0.5 1.2 1 0 0 1 1 1 0 Nucleoside transporter Inhibitor_I71 PF12628.2 ETO16214.1 - 0.49 10.0 5.8 0.6 9.7 3.7 1.4 1 1 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor DUF1227 PF06777.6 ETO16215.1 - 3.1e-40 137.2 4.0 1.9e-37 128.1 0.4 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 ETO16215.1 - 3.2e-09 36.4 0.1 6e-09 35.5 0.1 1.5 1 0 0 1 1 1 1 DEAD_2 DUF1722 PF08349.6 ETO16215.1 - 0.023 14.5 2.7 0.49 10.2 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF496 PF04363.7 ETO16215.1 - 0.07 12.9 2.1 0.24 11.2 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF496) Helicase_C_2 PF13307.1 ETO16216.1 - 2e-39 135.2 0.8 9e-20 71.2 0.1 2.3 2 0 0 2 2 2 2 Helicase C-terminal domain Cellulose_synt PF03552.9 ETO16217.1 - 1.1 7.4 3.8 1.5 7.0 2.6 1.1 1 0 0 1 1 1 0 Cellulose synthase RP-C_C PF11800.3 ETO16217.1 - 4.6 6.8 5.8 8 6.1 4.0 1.5 1 1 0 1 1 1 0 Replication protein C C-terminal region Syntaxin PF00804.20 ETO16217.1 - 4.9 7.3 14.8 2.1 8.5 5.3 2.9 1 1 1 2 2 2 0 Syntaxin Lumazine_bd PF12870.2 ETO16218.1 - 6.9 6.7 19.0 0.016 15.2 4.3 3.2 3 0 0 3 3 3 0 Lumazine-binding domain EF-hand_1 PF00036.27 ETO16219.1 - 3.8e-21 72.7 4.7 0.00016 20.7 0.2 4.7 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 ETO16219.1 - 5.8e-18 64.8 5.7 3.1e-09 36.8 1.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO16219.1 - 2.2e-16 58.1 5.9 0.0011 18.6 0.4 4.8 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 ETO16219.1 - 2.4e-13 49.4 9.7 0.00021 20.8 0.2 4.8 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.1 ETO16219.1 - 3.8e-10 38.6 3.8 0.004 16.4 0.2 4.8 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.2 ETO16219.1 - 4.6e-05 23.0 2.4 0.079 12.6 0.1 3.4 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 ETO16219.1 - 0.00011 21.9 0.0 0.23 11.3 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain TPR_11 PF13414.1 ETO16220.1 - 4e-09 36.0 11.3 1.4e-08 34.2 1.5 3.0 1 1 2 3 3 3 2 TPR repeat TPR_14 PF13428.1 ETO16220.1 - 3e-05 24.2 0.8 0.0028 18.1 0.1 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO16220.1 - 8.5e-05 22.4 6.3 0.24 11.7 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO16220.1 - 9.3e-05 22.2 7.4 0.13 12.1 1.5 2.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO16220.1 - 0.0069 16.2 0.3 0.0069 16.2 0.2 3.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO16220.1 - 0.0074 16.5 2.7 0.0074 16.5 1.9 2.5 2 2 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO16220.1 - 0.012 15.1 5.4 0.3 10.7 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETO16220.1 - 0.013 16.1 3.5 0.017 15.7 1.4 2.0 2 1 1 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 ETO16220.1 - 0.032 14.1 4.8 2.6 7.9 0.2 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.1 ETO16220.1 - 0.08 12.7 3.9 1.3 9.0 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 ETO16220.1 - 0.41 10.8 10.5 0.053 13.6 1.7 2.8 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 ETO16220.1 - 1.5 8.7 9.0 6 6.8 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF480 PF04337.7 ETO16221.1 - 0.0071 16.1 2.2 1.8 8.4 0.1 2.2 1 1 1 2 2 2 2 Protein of unknown function, DUF480 Arf PF00025.16 ETO16222.1 - 8.2e-12 44.7 0.0 0.00034 19.8 0.0 3.9 3 1 0 3 3 3 3 ADP-ribosylation factor family OrfB_Zn_ribbon PF07282.6 ETO16223.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Peptidase_S64 PF08192.6 ETO16224.1 - 2 6.6 14.4 2.3 6.4 10.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF2217 PF10265.4 ETO16224.1 - 4.3 5.9 9.2 4.5 5.9 6.4 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) RR_TM4-6 PF06459.7 ETO16225.1 - 0.15 11.9 9.9 0.24 11.2 6.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HGTP_anticodon2 PF12745.2 ETO16225.1 - 0.42 9.7 11.1 0.43 9.6 7.7 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs HRXXH PF13933.1 ETO16225.1 - 0.52 9.6 4.9 0.61 9.4 3.4 1.1 1 0 0 1 1 1 0 Putative peptidase family Exonuc_VII_L PF02601.10 ETO16225.1 - 1 8.5 12.5 1.1 8.4 8.7 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4613 PF15390.1 ETO16225.1 - 1.1 7.3 7.6 1.2 7.1 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) UPF0233 PF06781.7 ETO16225.1 - 5 6.8 11.1 1.4e+02 2.1 7.7 2.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0233) Phage_capsid PF05065.8 ETO16226.1 - 3.5e-43 147.7 0.2 5.2e-43 147.2 0.1 1.3 1 0 0 1 1 1 1 Phage capsid family PRP21_like_P PF12230.3 ETO16226.1 - 0.0022 17.5 0.1 0.0031 17.0 0.1 1.2 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Lac_bphage_repr PF06543.7 ETO16226.1 - 0.022 14.2 0.1 0.055 13.0 0.1 1.6 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor BBP1_C PF15272.1 ETO16226.1 - 0.046 13.2 1.5 0.069 12.6 1.0 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Peptidase_U35 PF04586.12 ETO16227.1 - 6.7e-31 107.5 0.0 8.5e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Caudovirus prohead protease Phage_portal PF04860.7 ETO16228.1 - 5.1e-73 245.7 0.0 6e-73 245.4 0.0 1.0 1 0 0 1 1 1 1 Phage portal protein Nsp1_C PF05064.8 ETO16229.1 - 0.088 12.4 5.6 0.17 11.5 3.9 1.7 1 1 0 1 1 1 0 Nsp1-like C-terminal region FlaC_arch PF05377.6 ETO16229.1 - 0.22 11.4 4.6 0.27 11.1 0.8 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF1510 PF07423.6 ETO16229.1 - 0.44 9.8 17.3 0.11 11.7 10.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1510) CENP-T PF15511.1 ETO16229.1 - 5.9 6.0 11.4 6.9 5.8 7.9 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T zf-RING_5 PF14634.1 ETO16230.1 - 2e-06 27.4 9.2 6e-06 25.8 6.4 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 ETO16230.1 - 1.5e-05 24.5 7.5 1.5e-05 24.5 5.2 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 ETO16230.1 - 1.9e-05 24.2 4.2 1.9e-05 24.2 2.9 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.1 ETO16230.1 - 1.9e-05 24.3 6.0 4.4e-05 23.2 4.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO16230.1 - 0.00065 19.6 9.5 0.0036 17.2 6.5 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 ETO16230.1 - 0.0069 16.2 9.6 0.0072 16.1 4.8 2.5 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING FlbT PF07378.6 ETO16230.1 - 0.076 12.8 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Flagellar protein FlbT zf-RING_6 PF14835.1 ETO16230.1 - 0.19 11.5 1.8 0.45 10.3 1.3 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein FYVE PF01363.16 ETO16230.1 - 2.6 8.0 6.6 8.6 6.3 4.6 1.9 1 1 0 1 1 1 0 FYVE zinc finger DENN PF02141.16 ETO16231.1 - 6e-50 169.5 2.7 6e-50 169.5 1.9 2.1 2 0 0 2 2 2 1 DENN (AEX-3) domain dDENN PF03455.14 ETO16231.1 - 2e-14 53.3 1.9 2e-14 53.3 1.3 2.3 2 0 0 2 2 2 1 dDENN domain uDENN PF03456.13 ETO16231.1 - 1.2e-12 47.5 0.1 3.3e-12 46.2 0.1 1.8 1 0 0 1 1 1 1 uDENN domain MMR_HSR1 PF01926.18 ETO16232.1 - 0.00022 21.1 2.5 0.00073 19.4 0.0 3.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase ABC_tran PF00005.22 ETO16232.1 - 0.00046 20.4 0.1 0.00046 20.4 0.1 4.4 4 1 0 4 4 4 1 ABC transporter DUF258 PF03193.11 ETO16232.1 - 0.0007 18.8 0.1 0.0007 18.8 0.1 3.0 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 ETO16232.1 - 0.0037 17.2 0.3 1.2 9.0 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain T2SE PF00437.15 ETO16232.1 - 0.0038 16.1 0.0 0.012 14.5 0.0 1.8 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 ETO16232.1 - 0.0051 16.3 0.1 0.018 14.5 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_19 PF13245.1 ETO16232.1 - 0.18 11.5 0.0 0.48 10.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 ETO16232.1 - 1.2 8.9 5.3 0.46 10.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 ETO16232.1 - 8.7 6.5 9.0 4.9 7.3 0.0 4.3 4 2 1 5 5 5 0 AAA domain CDC27 PF09507.5 ETO16233.1 - 0.055 12.6 26.5 0.077 12.2 18.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Hid1 PF12722.2 ETO16233.1 - 0.07 10.8 16.1 0.097 10.3 11.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MIP-T3 PF10243.4 ETO16233.1 - 0.11 10.9 30.9 0.16 10.3 21.4 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Nop14 PF04147.7 ETO16233.1 - 0.32 8.8 41.6 0.48 8.2 28.8 1.2 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 ETO16233.1 - 0.51 9.5 23.5 0.68 9.1 16.3 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TB2_DP1_HVA22 PF03134.14 ETO16234.1 - 0.013 15.1 0.1 0.013 15.1 0.0 1.8 2 0 0 2 2 2 0 TB2/DP1, HVA22 family Erf4 PF10256.4 ETO16235.1 - 0.071 12.9 2.1 0.087 12.6 0.5 2.0 2 1 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family GP11 PF08677.5 ETO16235.1 - 0.1 11.7 1.4 0.18 10.9 0.9 1.3 1 0 0 1 1 1 0 GP11 baseplate wedge protein DUF262 PF03235.9 ETO16235.1 - 0.8 9.6 8.7 1.1 9.2 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 Tom37_C PF11801.3 ETO16235.1 - 0.97 9.2 14.1 1.2 8.9 8.8 1.9 1 1 1 2 2 2 0 Tom37 C-terminal domain Reprolysin_3 PF13582.1 ETO16235.1 - 1.3 9.5 4.1 7.3 7.1 0.0 2.4 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Presenilin PF01080.12 ETO16235.1 - 1.6 7.4 4.5 1.9 7.2 3.1 1.1 1 0 0 1 1 1 0 Presenilin Ferritin PF00210.19 ETO16235.1 - 1.7 8.3 10.9 5.7 6.6 0.3 2.2 2 0 0 2 2 2 0 Ferritin-like domain YjgP_YjgQ PF03739.9 ETO16235.1 - 3.4 6.3 6.0 5.2 5.6 4.2 1.5 1 1 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF342 PF03961.8 ETO16235.1 - 7.4 4.8 15.0 9 4.5 10.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) zf-MYND PF01753.13 ETO16236.1 - 2.9e-06 27.0 22.5 4.5e-05 23.2 10.9 2.6 2 0 0 2 2 2 2 MYND finger ETRAMP PF09716.5 ETO16236.1 - 0.0081 16.0 0.2 0.066 13.1 0.1 2.5 1 1 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) DUF1639 PF07797.9 ETO16236.1 - 0.045 13.1 5.6 0.42 10.0 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1639) SAGA-Tad1 PF12767.2 ETO16236.1 - 0.12 11.9 13.7 0.16 11.6 9.5 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit LMBR1 PF04791.11 ETO16236.1 - 0.27 9.7 2.7 0.55 8.7 1.8 1.6 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF605 PF04652.11 ETO16236.1 - 0.29 10.4 29.1 0.36 10.1 20.2 1.1 1 0 0 1 1 1 0 Vta1 like Neur_chan_memb PF02932.11 ETO16236.1 - 0.42 10.4 12.7 0.82 9.5 6.4 2.0 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF1421 PF07223.6 ETO16236.1 - 4.4 6.9 48.8 5.9 6.5 33.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) GET2 PF08690.5 ETO16236.1 - 7.1 5.7 16.5 12 5.0 11.4 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 CMV_1a PF12467.3 ETO16236.1 - 7.9 6.8 15.6 32 4.8 10.8 1.8 1 1 0 1 1 1 0 Cucumber mosaic virus 1a protein family SAM_1 PF00536.25 ETO16238.1 - 1.5e-10 41.0 0.0 3.4e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO16238.1 - 1.3e-08 34.5 0.0 2.7e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 ETO16238.1 - 0.00019 21.1 0.0 0.00045 19.9 0.0 1.7 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain RasGEF PF00617.14 ETO16239.1 - 2.1e-29 102.5 2.5 8.6e-17 61.4 0.1 2.9 2 1 1 3 3 3 2 RasGEF domain RasGEF_N PF00618.15 ETO16239.1 - 3e-11 43.3 1.6 9.2e-11 41.7 0.1 2.5 2 0 0 2 2 2 1 RasGEF N-terminal motif UCH PF00443.24 ETO16240.1 - 4.4e-36 124.3 3.1 8.4e-36 123.4 2.2 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO16240.1 - 4.3e-21 75.6 3.1 8.9e-21 74.5 2.2 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HEAT PF02985.17 ETO16241.1 - 0.11 12.5 0.1 2.2e+02 2.3 0.0 4.4 3 1 1 4 4 4 0 HEAT repeat WD40 PF00400.27 ETO16242.1 - 1.3e-12 47.1 5.3 4.5e-09 35.8 0.2 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO16242.1 - 0.00045 19.0 0.1 0.00052 18.8 0.0 1.0 1 0 0 1 1 1 1 Nup133 N terminal like Beach PF02138.13 ETO16243.1 - 1.1e-51 175.8 0.2 1.2e-51 175.7 0.1 1.0 1 0 0 1 1 1 1 Beige/BEACH domain DUF1430 PF07242.6 ETO16244.1 - 0.024 14.7 0.9 0.024 14.7 0.7 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1430) HEAT PF02985.17 ETO16244.1 - 0.071 13.2 8.3 25 5.2 0.2 6.0 6 0 0 6 6 6 0 HEAT repeat Polysacc_deac_1 PF01522.16 ETO16244.1 - 0.11 12.0 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide deacetylase HEAT_EZ PF13513.1 ETO16244.1 - 0.38 11.2 2.1 1.7e+02 2.8 0.0 4.5 5 0 0 5 5 5 0 HEAT-like repeat HH_signal PF01085.13 ETO16245.1 - 0.013 15.0 0.1 0.029 13.9 0.1 1.6 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain AWPM-19 PF05512.6 ETO16245.1 - 0.044 13.7 0.3 0.098 12.6 0.1 1.6 1 1 0 1 1 1 0 AWPM-19-like family PH PF00169.24 ETO16246.1 - 5.2e-06 26.6 0.1 2e-05 24.7 0.1 2.0 1 0 0 1 1 1 1 PH domain Mcp5_PH PF12814.2 ETO16246.1 - 0.012 15.5 0.7 0.052 13.4 0.5 2.1 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology PH_11 PF15413.1 ETO16246.1 - 2.6 8.3 8.0 0.91 9.7 0.8 3.3 3 1 0 3 3 3 0 Pleckstrin homology domain DUF2205 PF10224.4 ETO16247.1 - 0.00063 19.2 6.5 0.00063 19.2 4.5 1.6 2 1 0 2 2 2 1 Predicted coiled-coil protein (DUF2205) DUF1875 PF08961.5 ETO16247.1 - 0.0084 15.4 3.3 0.01 15.1 2.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1875) NYD-SP28_assoc PF14775.1 ETO16247.1 - 0.033 13.8 2.1 0.033 13.8 1.5 2.4 2 2 1 3 3 3 0 Sperm tail C-terminal domain Ly49 PF08391.5 ETO16247.1 - 0.32 11.1 13.6 0.17 11.9 8.1 1.5 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region DUF4639 PF15479.1 ETO16247.1 - 0.8 8.2 6.0 0.85 8.1 4.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4639) NUDE_C PF04880.8 ETO16247.1 - 1.1 9.5 9.3 0.32 11.3 3.7 1.9 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region DUF972 PF06156.8 ETO16247.1 - 1.9 8.8 16.8 0.078 13.3 3.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Phage_B PF02304.10 ETO16247.1 - 2.4 8.4 7.6 2.2 8.6 4.7 1.4 1 1 0 1 1 1 0 Scaffold protein B Mem_trans PF03547.13 ETO16247.1 - 3.6 5.7 4.8 3.5 5.8 3.3 1.2 1 0 0 1 1 1 0 Membrane transport protein TMF_DNA_bd PF12329.3 ETO16248.1 - 0.014 15.1 1.6 0.014 15.1 1.1 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding T4_tail_cap PF11091.3 ETO16248.1 - 0.025 13.2 1.1 0.031 12.9 0.8 1.1 1 0 0 1 1 1 0 Tail-tube assembly protein TFIID_20kDa PF03847.8 ETO16249.1 - 2.4e-08 34.1 0.0 5e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 ETO16249.1 - 0.0033 17.4 0.1 0.0086 16.1 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.10 ETO16249.1 - 0.036 13.8 0.2 0.07 12.9 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 ETO16249.1 - 0.038 13.7 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated NAD_binding_1 PF00175.16 ETO16250.1 - 1.9e-20 73.4 0.0 4.9e-19 68.9 0.0 2.6 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 ETO16250.1 - 1.9e-16 59.9 0.0 3.7e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 ETO16250.1 - 6.9e-05 22.7 0.0 0.03 14.2 0.0 2.7 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 ETO16250.1 - 0.066 13.1 0.0 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain PKK PF12474.3 ETO16252.1 - 1.1 8.9 9.5 0.18 11.5 2.8 2.1 2 0 0 2 2 2 0 Polo kinase kinase PH PF00169.24 ETO16254.1 - 6.6e-06 26.2 0.5 6.6e-06 26.2 0.3 2.0 2 1 0 2 2 2 1 PH domain PH_11 PF15413.1 ETO16254.1 - 0.0069 16.6 1.9 0.0069 16.6 1.3 2.0 2 1 0 2 2 2 1 Pleckstrin homology domain DUF4487 PF14868.1 ETO16254.1 - 0.035 12.8 0.2 0.042 12.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4487) PH_6 PF15406.1 ETO16254.1 - 0.042 13.9 0.2 0.12 12.4 0.1 1.8 1 1 0 1 1 1 0 Pleckstrin homology domain Mcp5_PH PF12814.2 ETO16254.1 - 0.081 12.8 3.9 0.2 11.5 1.1 2.3 1 1 1 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology PH_4 PF15404.1 ETO16254.1 - 0.67 9.4 6.1 0.3 10.5 1.3 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain DUF563 PF04577.9 ETO16256.1 - 1.3e-10 41.6 0.0 2.3e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) RGS PF00615.14 ETO16257.1 - 4.7e-05 23.4 1.0 4.7e-05 23.4 0.7 1.8 2 0 0 2 2 2 1 Regulator of G protein signaling domain Cas_CT1975 PF09344.5 ETO16257.1 - 9.3e-05 21.9 0.7 9.3e-05 21.9 0.5 1.5 2 0 0 2 2 2 1 CT1975-like protein Sod_Ni PF09055.6 ETO16257.1 - 0.045 14.1 1.2 0.087 13.2 0.6 1.6 1 1 0 1 1 1 0 Nickel-containing superoxide dismutase DUF3991 PF13154.1 ETO16257.1 - 0.35 11.0 1.8 0.28 11.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3991) EF-hand_7 PF13499.1 ETO16258.1 - 8.8e-11 41.7 6.4 1.6e-10 40.9 0.8 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO16258.1 - 8.1e-08 31.0 10.2 0.0012 18.0 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 ETO16258.1 - 4.2e-07 29.0 3.1 0.014 14.7 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 ETO16258.1 - 1.3e-06 27.7 5.9 0.0035 17.0 0.1 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 ETO16258.1 - 3e-05 23.5 8.6 0.004 16.7 0.3 3.7 3 1 0 3 3 3 2 EF-hand domain pair RR_TM4-6 PF06459.7 ETO16258.1 - 0.064 13.1 20.3 0.09 12.6 14.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SprA-related PF12118.3 ETO16258.1 - 2.6 7.2 16.9 3.8 6.7 11.7 1.3 1 0 0 1 1 1 0 SprA-related family Zip PF02535.17 ETO16258.1 - 3.2 6.6 4.8 4.8 6.1 3.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter GAGA_bind PF06217.7 ETO16258.1 - 4 7.3 16.5 5.8 6.7 11.4 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family SpoIIIAH PF12685.2 ETO16258.1 - 4.2 6.8 22.3 3.2 7.2 7.1 2.5 2 1 0 2 2 2 0 SpoIIIAH-like protein Rootletin PF15035.1 ETO16259.1 - 0.0025 17.8 5.1 0.0048 16.8 3.5 1.5 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Herpes_UL6 PF01763.11 ETO16259.1 - 0.039 12.1 0.8 0.053 11.6 0.5 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like Metal_resist PF13801.1 ETO16259.1 - 0.044 13.7 4.1 0.1 12.5 2.9 1.7 1 0 0 1 1 1 0 Heavy-metal resistance KLRAQ PF10205.4 ETO16259.1 - 0.05 13.6 4.2 0.036 14.1 1.5 1.8 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein Wx5_PLAF3D7 PF09688.5 ETO16259.1 - 0.054 13.4 2.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) DUF4407 PF14362.1 ETO16259.1 - 0.06 12.2 2.5 0.065 12.1 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SLT PF01464.15 ETO16259.1 - 0.11 12.0 1.1 0.27 10.7 0.1 2.2 3 0 0 3 3 3 0 Transglycosylase SLT domain Nuc-transf PF10127.4 ETO16259.1 - 0.11 11.8 3.2 0.14 11.4 1.1 1.8 2 0 0 2 2 2 0 Predicted nucleotidyltransferase DUF1465 PF07323.7 ETO16259.1 - 0.12 11.9 3.0 0.85 9.1 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1465) DUF87 PF01935.12 ETO16259.1 - 0.37 10.5 2.6 0.5 10.1 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF87 SlyX PF04102.7 ETO16259.1 - 0.37 11.1 6.5 0.34 11.3 2.0 2.6 1 1 1 2 2 2 0 SlyX Tup_N PF08581.5 ETO16259.1 - 0.45 10.7 15.8 0.07 13.3 6.9 2.4 3 0 0 3 3 3 0 Tup N-terminal IncA PF04156.9 ETO16259.1 - 0.52 9.8 7.3 0.19 11.2 2.1 2.2 3 0 0 3 3 3 0 IncA protein DUF883 PF05957.8 ETO16259.1 - 0.83 10.0 5.4 0.63 10.4 2.2 1.9 2 0 0 2 2 1 0 Bacterial protein of unknown function (DUF883) OmpH PF03938.9 ETO16259.1 - 0.84 9.5 9.1 0.84 9.5 5.2 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Endotoxin_N PF03945.9 ETO16259.1 - 0.85 8.9 4.3 1.3 8.4 2.5 1.6 1 1 0 1 1 1 0 delta endotoxin, N-terminal domain Atg14 PF10186.4 ETO16259.1 - 1.9 7.3 6.6 1.1 8.0 2.3 1.9 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DivIVA PF05103.8 ETO16259.1 - 6.5 6.8 14.0 6.1 6.9 7.1 2.7 2 1 0 2 2 2 0 DivIVA protein Nefa_Nip30_N PF10187.4 ETO16261.1 - 0.0025 17.9 2.6 0.0049 17.0 1.8 1.5 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 MAT1 PF06391.8 ETO16261.1 - 0.015 14.9 3.5 0.016 14.7 2.4 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Mannitol_dh PF01232.18 ETO16261.1 - 0.059 13.3 1.3 0.15 12.0 0.9 1.6 1 1 1 2 2 2 0 Mannitol dehydrogenase Rossmann domain PAP_RNA-bind PF04926.10 ETO16261.1 - 0.074 12.5 0.8 0.092 12.2 0.6 1.2 1 0 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain TMA7 PF09072.5 ETO16261.1 - 2.9 8.4 8.3 2.7 8.5 3.2 2.5 2 1 1 3 3 3 0 Translation machinery associated TMA7 AAA PF00004.24 ETO16263.1 - 3.1e-37 127.7 0.2 7.6e-37 126.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PDZ PF00595.19 ETO16263.1 - 1.5e-06 28.2 0.0 3.5e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) FYVE PF01363.16 ETO16263.1 - 2.5e-06 27.2 13.2 6.3e-06 25.9 9.2 1.7 1 0 0 1 1 1 1 FYVE zinc finger AAA_22 PF13401.1 ETO16263.1 - 6.7e-05 23.0 0.2 0.0029 17.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 ETO16263.1 - 0.00016 20.8 0.0 0.00034 19.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 ETO16263.1 - 0.00037 20.2 0.0 0.0026 17.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 ETO16263.1 - 0.0037 16.0 0.0 0.0069 15.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 ETO16263.1 - 0.0067 15.6 0.0 0.02 14.0 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 ETO16263.1 - 0.017 15.0 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ABC2_membrane_3 PF12698.2 ETO16263.1 - 0.027 13.5 4.8 0.059 12.3 3.3 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein IstB_IS21 PF01695.12 ETO16263.1 - 0.079 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.1 ETO16263.1 - 0.41 11.4 0.0 0.41 11.4 0.0 3.0 4 1 0 4 4 3 0 AAA domain PDZ_2 PF13180.1 ETO16264.1 - 0.11 12.3 0.1 0.2 11.6 0.0 1.4 1 1 0 1 1 1 0 PDZ domain DUF3816 PF12822.2 ETO16264.1 - 0.15 11.9 2.4 8.7 6.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3816) DUF2663 PF10864.3 ETO16264.1 - 0.15 12.2 6.3 1.3 9.2 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) Tetraspannin PF00335.15 ETO16265.1 - 0.04 13.1 0.1 0.11 11.7 0.0 1.7 1 0 0 1 1 1 0 Tetraspanin family Prp31_C PF09785.4 ETO16265.1 - 0.046 14.1 1.7 0.12 12.8 1.2 1.7 1 1 0 1 1 1 0 Prp31 C terminal domain Exo_endo_phos PF03372.18 ETO16266.1 - 4.6e-07 30.0 0.2 2.9e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family RNase_H2-Ydr279 PF09468.5 ETO16266.1 - 0.59 9.2 17.5 3.8 6.6 11.7 2.0 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) Gly_transf_sug PF04488.10 ETO16267.1 - 2e-13 50.5 2.1 2.8e-13 50.1 0.7 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 ETO16267.1 - 0.00066 18.9 6.2 0.0008 18.6 3.4 1.9 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein A_deaminase_N PF08451.6 ETO16268.1 - 0.079 12.9 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Adenosine/AMP deaminase N-terminal MNSV_P7B PF06692.6 ETO16269.1 - 0.016 15.0 0.0 0.046 13.5 0.0 1.7 1 0 0 1 1 1 0 Melon necrotic spot virus P7B protein EphA2_TM PF14575.1 ETO16269.1 - 0.049 14.0 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FAM209 PF15206.1 ETO16269.1 - 0.099 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 FAM209 family DUF2615 PF11027.3 ETO16269.1 - 0.14 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) Lactamase_B PF00753.22 ETO16270.1 - 4e-09 36.4 0.0 4.5e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETO16270.1 - 5e-09 35.9 0.1 9.1e-09 35.1 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Alkyl_sulf_dimr PF14863.1 ETO16271.1 - 2e-13 50.7 0.1 7.4e-13 48.9 0.1 1.9 1 1 0 1 1 1 1 Alkyl sulfatase dimerisation Alkyl_sulf_C PF14864.1 ETO16271.1 - 0.012 15.5 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 0 Alkyl sulfatase C-terminal UCH PF00443.24 ETO16273.1 - 1.5e-16 60.3 0.6 2e-16 59.9 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Imm29 PF15575.1 ETO16273.1 - 0.04 13.5 0.1 0.095 12.2 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 29 DnaB PF00772.16 ETO16273.1 - 0.07 12.9 0.0 0.31 10.9 0.0 2.1 2 0 0 2 2 2 0 DnaB-like helicase N terminal domain DUF972 PF06156.8 ETO16274.1 - 0.014 15.7 16.7 0.27 11.6 1.2 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) ATG16 PF08614.6 ETO16274.1 - 0.034 13.9 12.1 0.075 12.8 8.3 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) GAS PF13851.1 ETO16274.1 - 0.082 12.0 18.3 0.016 14.4 7.7 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF633 PF04816.7 ETO16274.1 - 0.17 11.2 4.9 0.41 9.9 0.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF633) IncA PF04156.9 ETO16274.1 - 0.49 9.9 16.9 4.9 6.7 11.7 2.3 1 1 0 1 1 1 0 IncA protein Vir_act_alpha_C PF10400.4 ETO16274.1 - 0.75 10.2 3.5 7.2 7.0 0.3 2.5 1 1 0 2 2 2 0 Virulence activator alpha C-term Fib_alpha PF08702.5 ETO16274.1 - 1.1 9.3 11.7 0.14 12.2 5.3 1.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4164 PF13747.1 ETO16274.1 - 1.4 9.1 10.2 14 5.8 0.3 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) DivIC PF04977.10 ETO16274.1 - 4.6 6.7 18.4 0.21 11.0 0.4 3.5 3 1 1 4 4 4 0 Septum formation initiator adh_short PF00106.20 ETO16275.1 - 1.9e-14 53.9 0.0 8.9e-14 51.7 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETO16275.1 - 6.9e-08 32.3 0.0 9.8e-08 31.8 0.0 1.3 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETO16275.1 - 3.8e-05 23.5 0.0 7.9e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETO16275.1 - 0.00019 20.9 0.0 0.00026 20.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ETO16275.1 - 0.0027 16.6 0.0 0.0052 15.7 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 ETO16275.1 - 0.0083 16.1 0.0 0.022 14.7 0.0 1.8 1 1 1 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 ETO16275.1 - 0.015 14.2 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ank_2 PF12796.2 ETO16276.1 - 7.2e-08 32.6 0.0 1.2e-06 28.8 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO16276.1 - 1.8e-05 24.3 0.0 0.0056 16.4 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 ETO16276.1 - 3.7e-05 24.1 0.0 0.0011 19.4 0.0 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO16276.1 - 0.0036 17.4 0.1 0.54 10.5 0.0 2.8 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Nop14 PF04147.7 ETO16276.1 - 0.011 13.7 3.9 0.015 13.2 2.7 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 ETO16276.1 - 0.023 12.7 1.2 0.033 12.2 0.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Ank_3 PF13606.1 ETO16276.1 - 0.027 14.6 0.0 19 5.8 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeat Vfa1 PF08432.5 ETO16276.1 - 0.092 12.7 1.7 0.13 12.2 1.2 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TRAP_alpha PF03896.11 ETO16276.1 - 0.11 11.4 2.2 0.15 11.0 1.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RXT2_N PF08595.6 ETO16276.1 - 0.19 11.5 2.8 0.34 10.6 1.9 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal RP-C_C PF11800.3 ETO16276.1 - 5.4 6.6 6.6 3.5 7.2 0.6 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region HSP90 PF00183.13 ETO16276.1 - 7 4.9 7.1 9.5 4.4 4.9 1.1 1 0 0 1 1 1 0 Hsp90 protein EF-hand_1 PF00036.27 ETO16277.1 - 6.7e-31 103.2 21.0 1.1e-07 30.6 0.5 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 ETO16277.1 - 1.7e-26 92.0 11.4 3.8e-14 52.5 1.3 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO16277.1 - 7.7e-24 81.3 17.5 7.2e-07 28.5 0.0 5.2 3 3 3 6 6 6 4 EF-hand domain EF-hand_5 PF13202.1 ETO16277.1 - 2.6e-20 70.7 20.9 5.4e-07 28.6 0.9 5.2 4 2 1 5 5 5 4 EF hand EF-hand_8 PF13833.1 ETO16277.1 - 9.3e-19 66.8 20.4 1.5e-09 37.3 2.3 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.2 ETO16277.1 - 3.8e-08 33.0 8.0 2.8e-05 23.8 0.2 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 ETO16277.1 - 2.2e-07 30.8 1.5 0.0043 17.0 0.1 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 ETO16277.1 - 2.1e-06 27.5 2.1 0.00013 21.7 0.1 3.0 3 1 0 3 3 2 1 EF-hand domain Caleosin PF05042.8 ETO16277.1 - 9.1e-05 22.0 0.1 0.0042 16.6 0.0 2.3 2 0 0 2 2 2 1 Caleosin related protein Armet PF10208.4 ETO16277.1 - 0.0074 15.9 0.2 6 6.4 0.0 3.1 2 1 1 3 3 3 1 Degradation arginine-rich protein for mis-folding TerB PF05099.8 ETO16277.1 - 0.014 15.1 1.8 0.26 10.9 0.0 2.8 2 1 1 3 3 3 0 Tellurite resistance protein TerB VCBS PF13517.1 ETO16277.1 - 1.2 9.5 9.0 4.2 7.8 2.8 3.3 2 2 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Adaptin_binding PF10199.4 ETO16277.1 - 1.7 8.9 8.4 1.2 9.3 4.4 1.8 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Cohesin_load PF10345.4 ETO16278.1 - 0.019 13.1 0.6 0.023 12.9 0.4 1.0 1 0 0 1 1 1 0 Cohesin loading factor Nop14 PF04147.7 ETO16279.1 - 0.043 11.7 32.8 0.06 11.2 22.8 1.2 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.6 ETO16279.1 - 1.2 7.1 14.6 1.6 6.7 10.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NCKAP5 PF15246.1 ETO16280.1 - 0.23 10.8 3.0 0.24 10.7 2.1 1.0 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein FYDLN_acid PF09538.5 ETO16280.1 - 0.27 11.8 11.2 0.31 11.6 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) RNA_pol_3_Rpc31 PF11705.3 ETO16280.1 - 0.48 10.3 19.9 0.49 10.2 13.8 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.7 ETO16280.1 - 1.4 8.1 14.4 1.5 7.9 10.0 1.0 1 0 0 1 1 1 0 NOA36 protein Prothymosin PF03247.9 ETO16280.1 - 1.4 9.0 23.6 1.7 8.8 16.4 1.1 1 0 0 1 1 1 0 Prothymosin/parathymosin family Ribosomal_60s PF00428.14 ETO16280.1 - 1.9 8.9 11.8 2.6 8.5 8.1 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Sigma70_ner PF04546.8 ETO16280.1 - 4.2 6.9 12.3 4.4 6.8 8.5 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Pox_Ag35 PF03286.9 ETO16280.1 - 5.8 6.3 10.2 5.8 6.3 7.1 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Myc_N PF01056.13 ETO16280.1 - 6.8 5.7 10.2 7.5 5.6 7.1 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Nop14 PF04147.7 ETO16280.1 - 6.8 4.4 18.9 6.7 4.4 13.1 1.0 1 0 0 1 1 1 0 Nop14-like family Radial_spoke PF04712.7 ETO16280.1 - 6.9 5.2 10.8 7.2 5.2 7.5 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein CobT PF06213.7 ETO16280.1 - 7.1 5.6 15.1 6.5 5.7 10.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2457 PF10446.4 ETO16280.1 - 7.6 5.1 21.7 8.8 4.9 15.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PBP_sp32 PF07222.7 ETO16280.1 - 9.7 5.2 7.6 10 5.2 5.3 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Alpha_kinase PF02816.13 ETO16281.1 - 1.7e-41 141.9 0.1 1.7e-41 141.9 0.1 1.9 2 1 1 3 3 3 1 Alpha-kinase family mRNA_cap_enzyme PF01331.14 ETO16282.1 - 1.8e-06 27.7 0.0 3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain DSPc PF00782.15 ETO16282.1 - 0.016 14.7 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain CHAT PF12770.2 ETO16283.1 - 1.5e-09 37.4 0.1 1.9e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 CHAT domain Peptidase_C25 PF01364.13 ETO16283.1 - 0.012 14.5 0.2 0.016 14.1 0.2 1.2 1 0 0 1 1 1 0 Peptidase family C25 PhyH PF05721.8 ETO16285.1 - 3.2e-42 144.9 0.0 4.3e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Pkinase PF00069.20 ETO16288.1 - 6.1e-30 104.2 0.3 6.1e-30 104.2 0.2 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO16288.1 - 9.1e-17 60.9 0.0 1.8e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase CDC45 PF02724.9 ETO16288.1 - 0.0052 14.8 3.1 0.0079 14.2 2.1 1.4 1 0 0 1 1 1 1 CDC45-like protein PH PF00169.24 ETO16288.1 - 0.007 16.5 0.2 0.028 14.6 0.0 2.2 2 0 0 2 2 2 1 PH domain DZR PF12773.2 ETO16288.1 - 0.6 9.9 3.3 1.1 9.1 1.1 2.2 2 1 0 2 2 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 ETO16288.1 - 0.93 9.0 3.2 1 8.9 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Pkinase PF00069.20 ETO16289.1 - 0.037 13.1 0.0 0.075 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain Vpu PF00558.14 ETO16290.1 - 9.7 5.8 11.9 0.32 10.5 0.3 3.5 3 0 0 3 3 3 0 Vpu protein N6_Mtase PF02384.11 ETO16291.1 - 2.7e-29 102.2 0.1 3.4e-29 101.9 0.1 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase rve_3 PF13683.1 ETO16291.1 - 9.9e-08 31.3 0.6 6.8e-06 25.5 0.1 2.7 1 1 1 2 2 2 2 Integrase core domain rve PF00665.21 ETO16291.1 - 1.3e-05 25.2 0.0 2.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain UPF0020 PF01170.13 ETO16291.1 - 5.9e-05 22.7 0.0 8.4e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 ETO16291.1 - 0.0071 16.3 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DnaJ PF00226.26 ETO16292.1 - 9.5e-09 34.8 0.3 2.3e-08 33.6 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain N2227 PF07942.7 ETO16293.1 - 3.2e-85 285.4 0.6 7.1e-85 284.2 0.4 1.5 1 1 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 ETO16293.1 - 6.3e-05 22.7 0.0 0.00018 21.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO16293.1 - 0.011 15.3 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 ETO16293.1 - 0.042 14.3 0.0 0.73 10.3 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 ETO16293.1 - 0.07 13.7 0.0 0.41 11.2 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain DUF4465 PF14717.1 ETO16293.1 - 0.095 13.1 0.1 1.1 9.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4465) Pyr_redox_dim PF02852.17 ETO16294.1 - 2.4e-15 56.4 0.0 4.7e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 ETO16294.1 - 1.4e-07 31.5 0.0 3.2e-06 27.1 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETO16295.1 - 1.2e-12 48.0 0.0 1.4e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Menin PF05053.8 ETO16296.1 - 0.61 8.1 17.0 0.37 8.9 1.2 2.3 2 0 0 2 2 2 0 Menin MIP-T3 PF10243.4 ETO16298.1 - 0.015 13.7 35.5 0.02 13.3 24.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Macoilin PF09726.4 ETO16298.1 - 5 5.2 31.6 6.3 4.9 21.9 1.2 1 0 0 1 1 1 0 Transmembrane protein LMBR1 PF04791.11 ETO16298.1 - 9.1 4.7 10.0 11 4.4 7.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein COPIIcoated_ERV PF07970.7 ETO16299.1 - 3.2e-27 95.6 2.9 9.7e-27 94.0 2.0 1.6 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter CD36 PF01130.16 ETO16301.1 - 7.9e-15 54.1 7.8 4.3e-14 51.6 1.0 2.1 2 0 0 2 2 2 2 CD36 family SUD-M PF11633.3 ETO16301.1 - 0.092 12.0 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Single-stranded poly(A) binding domain SNARE PF05739.14 ETO16302.1 - 6.1e-07 29.0 2.1 6.1e-07 29.0 1.4 2.5 3 0 0 3 3 3 1 SNARE domain Golgin_A5 PF09787.4 ETO16302.1 - 0.24 9.8 15.0 0.16 10.4 9.2 1.5 1 1 0 1 1 1 0 Golgin subfamily A member 5 DUF837 PF05769.6 ETO16302.1 - 0.36 10.3 16.3 0.055 13.0 5.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF837) TBPIP PF07106.8 ETO16302.1 - 0.46 10.0 17.4 0.33 10.4 2.3 2.2 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Sulfatase_C PF14707.1 ETO16302.1 - 0.72 10.1 3.5 0.57 10.4 0.4 2.2 1 1 1 3 3 3 0 C-terminal region of aryl-sulfatase GLE1 PF07817.8 ETO16302.1 - 0.78 8.6 8.0 1.5 7.6 0.9 2.2 2 0 0 2 2 2 0 GLE1-like protein Sec20 PF03908.8 ETO16302.1 - 1.4 8.6 11.5 5.9 6.6 0.7 3.4 2 2 1 3 3 3 0 Sec20 Phasin PF05597.6 ETO16302.1 - 1.5 8.5 8.6 3.2 7.5 2.3 2.2 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Syntaxin-6_N PF09177.6 ETO16302.1 - 3.9 7.9 12.7 0.66 10.4 1.8 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FAM60A PF15396.1 ETO16302.1 - 4.4 6.9 13.6 5.2e+02 0.2 9.4 2.0 1 1 0 1 1 1 0 Protein Family FAM60A 5_3_exonuc PF01367.15 ETO16302.1 - 9 6.5 7.0 5.6 7.2 0.7 2.8 1 1 3 4 4 4 0 5'-3' exonuclease, C-terminal SAM fold Abhydrolase_6 PF12697.2 ETO16303.1 - 4.4e-10 39.8 0.0 6.3e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETO16303.1 - 5.4e-09 35.9 0.0 7.7e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 ETO16303.1 - 5.1e-07 29.3 0.2 3.3e-06 26.7 0.1 2.2 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 ETO16303.1 - 6.5e-07 28.7 0.3 8.1e-05 21.9 0.0 2.2 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 ETO16303.1 - 2.6e-06 27.1 0.4 0.00055 19.5 0.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold UPF0227 PF05728.7 ETO16303.1 - 9.4e-06 25.4 0.5 0.0065 16.2 0.1 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0227) Abhydrolase_2 PF02230.11 ETO16303.1 - 0.00066 19.1 0.1 0.43 9.9 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.5 ETO16303.1 - 0.011 15.5 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Peptidase_S10 PF00450.17 ETO16303.1 - 0.022 13.9 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase Abhydrolase_3 PF07859.8 ETO16303.1 - 0.035 13.6 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 ETO16303.1 - 0.1 12.0 0.3 0.28 10.5 0.2 1.7 1 1 0 1 1 1 0 Putative esterase 3HBOH PF10605.4 ETO16303.1 - 0.14 10.1 0.0 0.18 9.8 0.0 1.1 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) WD40 PF00400.27 ETO16304.1 - 9.1e-28 95.1 2.0 4.1e-07 29.6 0.0 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO16304.1 - 4.8e-06 26.5 3.7 0.064 13.4 0.1 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 ETO16304.1 - 0.0007 19.6 1.0 0.1 12.7 0.0 3.3 3 0 0 3 3 3 1 Galactose oxidase, central domain Cytochrom_D1 PF02239.11 ETO16304.1 - 0.00092 17.6 0.0 0.022 13.0 0.0 2.3 2 0 0 2 2 2 1 Cytochrome D1 heme domain Kelch_1 PF01344.20 ETO16304.1 - 0.001 18.5 9.0 0.26 10.8 0.1 4.0 4 0 0 4 4 4 2 Kelch motif Nup160 PF11715.3 ETO16304.1 - 0.0022 16.2 0.1 2.2 6.3 0.0 3.3 1 1 2 3 3 3 1 Nucleoporin Nup120/160 Kelch_2 PF07646.10 ETO16304.1 - 0.0023 17.6 4.6 0.92 9.3 0.1 3.6 3 1 0 3 3 3 2 Kelch motif PD40 PF07676.7 ETO16304.1 - 0.048 13.3 0.9 2.3 7.9 0.0 3.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Biotin_lipoyl_2 PF13533.1 ETO16304.1 - 0.061 12.9 0.1 2.8 7.6 0.0 2.6 2 0 0 2 2 2 0 Biotin-lipoyl like Kelch_5 PF13854.1 ETO16304.1 - 0.071 13.0 2.4 3.5 7.6 0.1 3.4 3 0 0 3 3 3 0 Kelch motif DUF3439 PF11921.3 ETO16305.1 - 0.027 14.1 1.7 0.078 12.7 1.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) GRAM PF02893.15 ETO16305.1 - 0.072 12.6 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 GRAM domain Neur_chan_memb PF02932.11 ETO16305.1 - 3.3 7.5 12.9 4 7.2 3.9 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF843 PF05814.6 ETO16305.1 - 8.4 6.2 7.9 0.27 11.0 0.9 1.9 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) UCH PF00443.24 ETO16306.1 - 1.3e-25 90.0 0.0 3e-24 85.5 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO16306.1 - 4.1e-09 36.3 0.0 1.3e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Actin PF00022.14 ETO16307.1 - 1.4e-13 50.0 0.0 1.8e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Actin DUF1168 PF06658.7 ETO16307.1 - 0.0027 17.2 5.0 0.004 16.6 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) NinG PF05766.7 ETO16307.1 - 0.017 14.8 1.0 0.027 14.2 0.7 1.2 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein PilM_2 PF11104.3 ETO16307.1 - 0.054 12.3 0.0 0.087 11.6 0.0 1.2 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; FGE-sulfatase PF03781.11 ETO16307.1 - 0.077 12.3 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Sulfatase-modifying factor enzyme 1 RCC1_2 PF13540.1 ETO16308.1 - 2.6e-06 26.8 0.2 1.2e-05 24.8 0.3 2.0 2 0 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 ETO16308.1 - 0.033 14.4 0.0 0.84 9.9 0.0 2.6 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat Rap_GAP PF02145.10 ETO16309.1 - 3.9e-12 45.9 0.1 1e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Rap/ran-GAP PT PF04886.7 ETO16311.1 - 1.1e-05 24.6 31.0 0.026 13.8 2.7 3.4 2 1 1 3 3 3 3 PT repeat TMEM154 PF15102.1 ETO16311.1 - 1.9e-05 24.4 0.5 0.0093 15.6 0.1 2.5 2 0 0 2 2 2 2 TMEM154 protein family DUF3609 PF12259.3 ETO16311.1 - 0.0011 17.6 0.1 0.0018 17.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3609) MGC-24 PF05283.6 ETO16311.1 - 0.016 14.9 10.1 0.016 14.9 7.0 1.6 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) DUF3377 PF11857.3 ETO16311.1 - 0.019 14.5 0.3 0.019 14.5 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) DUF4234 PF14018.1 ETO16311.1 - 0.07 12.8 0.2 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) DUF1052 PF06319.7 ETO16311.1 - 0.079 12.2 0.1 0.14 11.3 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1052) OAD_gamma PF04277.8 ETO16312.1 - 0.11 12.9 2.0 0.76 10.1 0.9 2.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Utp14 PF04615.8 ETO16313.1 - 0.35 8.9 19.6 0.45 8.6 13.6 1.0 1 0 0 1 1 1 0 Utp14 protein Macoilin PF09726.4 ETO16313.1 - 6.1 4.9 17.5 6.5 4.8 12.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Hid1 PF12722.2 ETO16313.1 - 8.2 3.9 24.3 11 3.5 16.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein IFT57 PF10498.4 ETO16314.1 - 0.0021 16.8 5.8 0.0021 16.8 4.0 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 DUF2856 PF11043.3 ETO16314.1 - 0.082 13.0 4.3 0.1 12.6 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2856) Rep_4 PF05797.6 ETO16314.1 - 0.14 10.7 4.5 0.17 10.5 3.1 1.1 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) GvpL_GvpF PF06386.6 ETO16314.1 - 0.17 11.4 4.3 0.19 11.2 3.0 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Peptidase_S49_N PF08496.5 ETO16314.1 - 0.32 10.7 11.7 0.38 10.5 8.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SPT16 PF08644.6 ETO16314.1 - 0.77 9.5 8.2 0.96 9.2 5.7 1.1 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Bap31 PF05529.7 ETO16314.1 - 1.3 8.4 8.8 1.4 8.3 6.1 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like SLX9 PF15341.1 ETO16314.1 - 3 8.2 15.4 3.8 7.9 10.6 1.2 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 Casc1 PF12366.3 ETO16314.1 - 3.3 7.1 7.3 3.9 6.8 5.1 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 Cut12 PF11500.3 ETO16314.1 - 3.8 7.1 16.1 4.4 6.9 11.1 1.2 1 0 0 1 1 1 0 Spindle pole body formation-associated protein Atg14 PF10186.4 ETO16314.1 - 7.2 5.4 8.7 7.6 5.3 6.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SR-25 PF10500.4 ETO16314.1 - 7.4 5.9 19.2 9.3 5.6 13.3 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Vfa1 PF08432.5 ETO16316.1 - 0.54 10.2 8.7 0.62 10.0 6.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FAM176 PF14851.1 ETO16316.1 - 4.4 6.9 6.1 6 6.5 4.2 1.2 1 0 0 1 1 1 0 FAM176 family Dev_Cell_Death PF10539.4 ETO16318.1 - 1.9e-23 82.4 0.0 3.5e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Development and cell death domain Ras PF00071.17 ETO16321.1 - 0.0031 16.8 0.4 0.09 12.1 0.3 2.5 1 1 0 1 1 1 1 Ras family 60KD_IMP PF02096.15 ETO16322.1 - 0.0048 16.5 0.4 0.015 14.9 0.0 1.9 2 0 0 2 2 2 1 60Kd inner membrane protein PBP1_TM PF14812.1 ETO16322.1 - 0.66 10.3 5.8 0.15 12.3 0.3 2.5 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WD40 PF00400.27 ETO16323.1 - 8.4e-73 237.8 12.2 2.8e-13 49.1 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO16323.1 - 1.1e-08 33.7 9.2 0.041 12.0 0.3 5.6 1 1 3 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO16323.1 - 2e-06 26.8 13.0 0.49 9.0 0.5 5.1 1 1 5 6 6 6 4 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO16323.1 - 9.1e-06 24.2 4.1 0.0033 15.7 0.1 3.5 2 1 2 4 4 4 2 Cytochrome D1 heme domain DUF3601 PF12208.3 ETO16323.1 - 0.026 14.4 0.5 11 6.0 0.1 4.0 2 2 2 4 4 4 0 Domain of unknown function (DUF3601) PD40 PF07676.7 ETO16323.1 - 0.074 12.7 5.7 17 5.2 0.0 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO16323.1 - 0.089 13.0 0.0 6.2 7.1 0.0 3.1 2 1 1 3 3 3 0 Resistin PIP5K PF01504.13 ETO16324.1 - 1e-53 182.0 0.1 2.5e-53 180.7 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase PLDc_3 PF13918.1 ETO16324.1 - 0.066 12.6 0.0 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 PLD-like domain MMPL PF03176.10 ETO16326.1 - 4.4e-11 42.0 0.0 5.9e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 MMPL family Sulfotransfer_1 PF00685.22 ETO16327.1 - 1.7e-08 34.0 7.4 1.8e-08 33.9 4.5 1.3 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 ETO16327.1 - 0.0015 19.4 1.3 0.0023 18.8 0.9 1.4 1 1 0 1 1 1 1 Sulfotransferase family COX14 PF14880.1 ETO16327.1 - 0.21 11.2 2.4 2.7 7.6 0.0 3.2 3 0 0 3 3 3 0 Cytochrome oxidase c assembly PH_11 PF15413.1 ETO16328.1 - 2.2e-08 34.3 0.9 2.2e-08 34.3 0.6 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 ETO16328.1 - 8.1e-07 29.2 9.6 1.2e-06 28.6 3.3 2.6 2 1 0 2 2 2 1 PH domain PH_8 PF15409.1 ETO16328.1 - 0.024 14.6 3.0 0.24 11.5 0.7 2.8 2 1 0 2 2 2 0 Pleckstrin homology domain DUF809 PF05663.6 ETO16328.1 - 0.048 13.5 2.2 0.088 12.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF809) RP-C_C PF11800.3 ETO16328.1 - 0.12 12.0 0.4 0.2 11.3 0.3 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Trypan_PARP PF05887.6 ETO16328.1 - 0.15 11.8 3.7 0.28 10.9 2.5 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Nop14 PF04147.7 ETO16328.1 - 1.7 6.4 11.7 2.2 6.0 8.1 1.1 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 ETO16328.1 - 2.2 7.8 11.3 3.6 7.1 7.8 1.3 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 ETO16328.1 - 3.1 6.9 9.0 5 6.2 6.2 1.2 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.4 ETO16328.1 - 5.9 5.5 13.2 8.4 4.9 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.5 ETO16328.1 - 8.3 6.7 14.7 22 5.3 10.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PH PF00169.24 ETO16329.1 - 4.2e-21 75.1 7.3 1.4e-12 47.7 2.6 3.2 2 1 0 2 2 2 2 PH domain PH_11 PF15413.1 ETO16329.1 - 5.7e-13 49.0 5.2 1.6e-05 25.0 0.1 3.2 3 0 0 3 3 3 2 Pleckstrin homology domain PH_8 PF15409.1 ETO16329.1 - 3.9e-09 36.4 6.8 0.0033 17.4 0.2 3.8 4 0 0 4 4 4 2 Pleckstrin homology domain PH_3 PF14593.1 ETO16329.1 - 6.4e-07 29.2 1.5 0.26 11.2 0.1 3.4 3 0 0 3 3 3 3 PH domain Adenylate_cycl PF01295.13 ETO16329.1 - 0.1 10.8 0.5 0.15 10.2 0.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase, class-I PH_4 PF15404.1 ETO16329.1 - 0.56 9.7 3.5 0.78 9.2 0.4 2.6 3 1 1 4 4 4 0 Pleckstrin homology domain AF-4 PF05110.8 ETO16330.1 - 0.77 7.5 11.0 1 7.1 7.6 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PRP21_like_P PF12230.3 ETO16330.1 - 7.6 5.9 14.4 2.5 7.5 7.4 1.8 1 1 1 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein C2 PF00168.25 ETO16331.1 - 7.4e-37 125.0 0.3 3.3e-18 65.2 0.3 2.7 2 0 0 2 2 2 2 C2 domain Aconitase PF00330.15 ETO16331.1 - 0.5 8.7 7.4 0.82 8.0 5.1 1.2 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) SPRY PF00622.23 ETO16332.1 - 2.9e-16 59.6 0.0 4.9e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 SPRY domain UQ_con PF00179.21 ETO16332.1 - 7e-07 28.7 0.1 1.1e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pam17 PF08566.5 ETO16333.1 - 0.031 13.9 1.0 2.3 7.8 0.7 2.5 1 1 0 1 1 1 0 Mitochondrial import protein Pam17 Ribosomal_L7Ae PF01248.21 ETO16334.1 - 2.4e-14 52.5 0.1 1.4e-08 34.1 0.1 2.5 3 0 0 3 3 3 2 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family VWA_2 PF13519.1 ETO16335.1 - 0.064 13.3 0.0 0.066 13.3 0.0 1.1 1 0 0 1 1 1 0 von Willebrand factor type A domain SbcCD_C PF13558.1 ETO16336.1 - 0.15 11.9 0.2 0.24 11.3 0.1 1.2 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ArfGap PF01412.13 ETO16337.1 - 1.5e-10 40.8 0.8 3.9e-10 39.5 0.0 1.9 1 1 1 2 2 2 1 Putative GTPase activating protein for Arf SR-25 PF10500.4 ETO16338.1 - 5.9 6.2 18.5 0.52 9.7 0.3 3.6 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein zf-C2H2_4 PF13894.1 ETO16339.1 - 0.00084 19.5 0.8 0.0031 17.7 0.5 2.1 1 0 0 1 1 1 1 C2H2-type zinc finger Arrestin_C PF02752.17 ETO16339.1 - 0.0018 18.4 1.8 0.68 10.0 0.8 2.8 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain zf-C2H2 PF00096.21 ETO16339.1 - 0.0019 18.4 1.6 0.0072 16.6 1.1 2.1 1 0 0 1 1 1 1 Zinc finger, C2H2 type Apis_Csd PF11671.3 ETO16339.1 - 0.014 15.2 8.1 0.014 15.2 5.6 3.2 4 0 0 4 4 4 0 Complementary sex determiner protein zf-Di19 PF05605.7 ETO16339.1 - 0.033 14.3 2.2 0.051 13.6 0.8 1.9 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Methyltransf_12 PF08242.7 ETO16339.1 - 7.9 7.0 9.5 1.6 9.2 0.4 3.3 3 0 0 3 3 3 0 Methyltransferase domain WD40 PF00400.27 ETO16340.1 - 1.5e-160 516.0 39.7 3.7e-13 48.8 0.0 16.2 16 0 0 16 16 16 16 WD domain, G-beta repeat Nup160 PF11715.3 ETO16340.1 - 8.9e-13 47.2 33.6 0.62 8.1 0.1 12.8 1 1 11 12 12 12 10 Nucleoporin Nup120/160 Str_synth PF03088.11 ETO16340.1 - 1.2e-06 28.4 0.9 6.5 6.8 0.0 7.1 6 3 1 7 7 7 1 Strictosidine synthase Pentapeptide PF00805.17 ETO16340.1 - 1.7e-05 23.8 0.7 4e-05 22.7 0.5 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO16340.1 - 7.8e-05 22.4 0.5 0.00023 20.8 0.4 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Mid2 PF04478.7 ETO16340.1 - 0.0018 17.7 7.9 4.9 6.5 0.1 7.2 6 2 3 9 9 9 1 Mid2 like cell wall stress sensor Pentapeptide_3 PF13576.1 ETO16340.1 - 0.003 17.4 0.9 0.003 17.4 0.6 2.2 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) Interfer-bind PF09294.5 ETO16340.1 - 0.063 13.3 0.2 0.37 10.8 0.1 2.4 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III eIF-3c_N PF05470.7 ETO16342.1 - 0.07 11.2 2.1 0.12 10.4 1.5 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RskA PF10099.4 ETO16344.1 - 0.0013 18.5 4.5 0.0029 17.3 3.2 1.6 1 0 0 1 1 1 1 Anti-sigma-K factor rskA ELMO_CED12 PF04727.8 ETO16344.1 - 0.017 14.6 0.1 0.044 13.3 0.1 1.7 1 0 0 1 1 1 0 ELMO/CED-12 family SpoVR PF04293.8 ETO16346.1 - 0.059 11.7 1.9 0.098 11.0 1.3 1.3 1 0 0 1 1 1 0 SpoVR like protein DUF399 PF04187.8 ETO16347.1 - 3.3e-27 95.3 0.0 3.9e-26 91.8 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF399 Pkinase PF00069.20 ETO16350.1 - 1.2e-55 188.4 0.0 1.2e-55 188.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain EF-hand_1 PF00036.27 ETO16350.1 - 8.1e-26 87.3 10.0 1.4e-06 27.2 0.1 4.7 4 0 0 4 4 4 4 EF hand Pkinase_Tyr PF07714.12 ETO16350.1 - 1.3e-25 89.9 0.0 4.4e-25 88.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase EF-hand_5 PF13202.1 ETO16350.1 - 1.9e-20 71.1 6.8 3.5e-07 29.2 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 ETO16350.1 - 6.4e-19 66.0 5.8 2.1e-06 27.1 0.0 4.8 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 ETO16350.1 - 1.7e-18 66.4 11.6 3.1e-09 36.8 0.1 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 ETO16350.1 - 3.1e-18 65.1 4.2 5.3e-05 22.7 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain pair Kdo PF06293.9 ETO16350.1 - 2.4e-06 26.7 0.0 5.6e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SPARC_Ca_bdg PF10591.4 ETO16350.1 - 2.4e-06 27.5 11.9 0.00085 19.3 0.0 4.1 1 1 2 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region APH PF01636.18 ETO16350.1 - 0.00084 19.1 0.1 0.051 13.2 0.1 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 ETO16350.1 - 0.0012 18.2 1.3 0.0037 16.6 0.0 2.3 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL EF-hand_9 PF14658.1 ETO16350.1 - 0.023 14.6 0.1 6.1 6.8 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain Atrophin-1 PF03154.10 ETO16350.1 - 0.42 8.6 2.9 0.6 8.1 2.0 1.1 1 0 0 1 1 1 0 Atrophin-1 family BSMAP PF12280.3 ETO16350.1 - 0.44 10.3 4.5 0.11 12.3 0.8 1.6 2 0 0 2 2 1 0 Brain specific membrane anchored protein DUF2722 PF10846.3 ETO16350.1 - 0.69 8.8 11.5 1.3 7.9 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) POX PF07526.6 ETO16350.1 - 0.78 9.9 9.7 0.035 14.3 2.5 1.8 2 0 0 2 2 2 0 Associated with HOX Sec62 PF03839.11 ETO16350.1 - 1.1 8.5 8.7 2.9 7.2 6.0 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 EF-hand_4 PF12763.2 ETO16350.1 - 1.7 8.3 13.2 15 5.3 1.8 4.0 2 1 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand NDK PF00334.14 ETO16351.1 - 4.6e-31 107.4 0.1 6.6e-30 103.6 0.1 2.4 2 1 0 2 2 2 1 Nucleoside diphosphate kinase Dpy-30 PF05186.8 ETO16351.1 - 0.0041 16.5 0.0 0.011 15.2 0.0 1.7 1 0 0 1 1 1 1 Dpy-30 motif AAA_24 PF13479.1 ETO16351.1 - 0.11 12.0 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF2510 PF10708.4 ETO16352.1 - 0.1 12.0 0.9 10 5.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2510) AAA_13 PF13166.1 ETO16353.1 - 0.0067 14.9 7.9 0.01 14.3 5.5 1.3 1 0 0 1 1 1 1 AAA domain RPN7 PF10602.4 ETO16353.1 - 0.093 12.1 0.0 0.093 12.1 0.0 3.3 2 1 2 4 4 4 0 26S proteasome subunit RPN7 Vps39_1 PF10366.4 ETO16353.1 - 0.23 11.4 3.5 4.5 7.3 0.9 2.7 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 Pinin_SDK_memA PF04696.8 ETO16353.1 - 0.65 9.5 24.5 1.5 8.3 17.0 1.6 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region DUF3584 PF12128.3 ETO16353.1 - 2.7 5.2 20.9 4 4.6 14.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DDRGK PF09756.4 ETO16353.1 - 4.3 6.6 28.5 8 5.8 19.8 1.4 1 0 0 1 1 1 0 DDRGK domain Vps53_N PF04100.7 ETO16354.1 - 6.4e-28 97.6 2.8 7.7e-28 97.3 1.9 1.0 1 0 0 1 1 1 1 Vps53-like, N-terminal UBN2_2 PF14227.1 ETO16354.1 - 0.0041 16.6 0.9 0.0066 15.9 0.6 1.4 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF2854 PF11016.3 ETO16354.1 - 0.02 14.4 0.1 0.053 13.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) FDF PF09532.5 ETO16355.1 - 0.025 15.1 2.7 0.027 15.0 1.9 1.2 1 0 0 1 1 1 0 FDF domain AfaD PF05775.7 ETO16355.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Enterobacteria AfaD invasin protein DUF3116 PF11313.3 ETO16358.1 - 0.065 12.8 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3116) HAS-barrel PF09378.5 ETO16358.1 - 0.13 12.2 0.1 0.52 10.2 0.0 2.0 2 0 0 2 2 2 0 HAS barrel domain Aminotran_1_2 PF00155.16 ETO16359.1 - 0.04 12.8 0.1 0.083 11.8 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class I and II OppC_N PF12911.2 ETO16361.1 - 0.006 15.9 0.0 0.013 14.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal TM domain of oligopeptide transport permease C DUF1705 PF08019.7 ETO16361.1 - 0.058 12.9 1.2 2.7 7.4 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1705) SLBP_RNA_bind PF15247.1 ETO16364.1 - 1.3e-22 79.2 3.7 3.3e-22 78.0 0.7 2.4 1 1 1 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain DUF4064 PF13273.1 ETO16365.1 - 0.039 14.0 0.3 0.052 13.6 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) vATP-synt_AC39 PF01992.11 ETO16366.1 - 1.7e-20 73.4 0.0 2e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit DUF2709 PF10915.3 ETO16366.1 - 0.01 14.8 0.6 0.024 13.6 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2709) YopX PF09643.5 ETO16367.1 - 0.0036 17.2 3.6 0.0073 16.2 0.1 2.2 2 0 0 2 2 2 1 YopX protein CTC1_2 PF15491.1 ETO16367.1 - 0.055 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 UCH PF00443.24 ETO16368.1 - 5.7e-19 68.2 0.0 1.3e-17 63.8 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Bromodomain PF00439.20 ETO16371.1 - 2.9e-14 52.7 1.0 8.3e-10 38.4 0.0 3.9 3 2 1 4 4 4 3 Bromodomain CTDII PF01556.13 ETO16371.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 DnaJ C terminal domain ATG27 PF09451.5 ETO16372.1 - 0.0027 17.0 1.6 0.0066 15.7 0.1 2.0 2 0 0 2 2 2 1 Autophagy-related protein 27 Viral_Beta_CD PF04530.7 ETO16372.1 - 0.18 11.9 2.8 0.37 10.9 0.1 2.5 2 0 0 2 2 2 0 Viral Beta C/D like family MMPL PF03176.10 ETO16373.1 - 3.7e-33 114.6 14.6 8.2e-32 110.2 10.1 2.0 1 1 0 1 1 1 1 MMPL family CopD PF05425.8 ETO16373.1 - 9.7 6.4 21.1 2.9 8.1 2.5 2.9 1 1 1 2 2 2 0 Copper resistance protein D FYVE PF01363.16 ETO16375.1 - 2.3e-20 72.2 16.7 2.3e-20 72.2 11.6 1.8 2 0 0 2 2 2 1 FYVE zinc finger DUF4015 PF13200.1 ETO16375.1 - 0.11 11.3 0.4 0.18 10.6 0.3 1.3 1 0 0 1 1 1 0 Putative glycosyl hydrolase domain Mucin PF01456.12 ETO16375.1 - 4.5 7.0 30.5 0.21 11.3 16.9 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein ADK_lid PF05191.9 ETO16375.1 - 5 6.8 9.2 1.5 8.5 2.7 2.8 2 1 0 2 2 2 0 Adenylate kinase, active site lid C2 PF00168.25 ETO16376.1 - 7.3e-05 22.5 0.3 0.00022 21.0 0.0 1.9 2 0 0 2 2 2 1 C2 domain Exo_endo_phos PF03372.18 ETO16377.1 - 1e-13 51.8 0.0 1.5e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_C97 PF05903.9 ETO16378.1 - 4.1e-13 49.3 1.6 8.7e-13 48.3 1.1 1.5 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 ETO16378.1 - 0.056 13.3 1.9 0.35 10.8 0.1 2.3 2 0 0 2 2 2 0 Lecithin retinol acyltransferase LRR_4 PF12799.2 ETO16379.1 - 2.9e-20 71.4 62.6 7.9e-06 25.3 2.0 7.9 3 2 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO16379.1 - 1.4e-16 60.0 64.5 1.2e-06 28.1 4.3 6.6 2 1 7 9 9 9 9 Leucine rich repeat LRR_9 PF14580.1 ETO16379.1 - 3.1e-08 33.3 25.0 7.8e-05 22.3 0.1 3.9 3 1 1 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.1 ETO16379.1 - 0.0029 17.5 42.7 1.1 9.5 0.1 10.3 9 1 2 11 11 11 3 Leucine Rich repeat LRR_1 PF00560.28 ETO16379.1 - 2.4 8.5 57.7 1.7 8.9 0.3 11.3 12 0 0 12 12 12 0 Leucine Rich Repeat YPEB PF14620.1 ETO16380.1 - 0.007 15.4 1.3 0.0081 15.2 0.9 1.0 1 0 0 1 1 1 1 YpeB sporulation DUF2222 PF09984.4 ETO16380.1 - 0.053 12.9 1.6 0.096 12.1 1.0 1.5 1 1 1 2 2 2 0 Uncharacterized signal transduction histidine kinase domain (DUF2222) Beta-lactamase PF00144.19 ETO16381.1 - 1.3e-11 44.1 0.1 1.7e-11 43.7 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase CDC27 PF09507.5 ETO16382.1 - 1.4 8.0 62.7 1.9 7.6 43.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ank_4 PF13637.1 ETO16383.1 - 0.00072 20.0 0.3 0.02 15.4 0.1 3.3 3 1 0 3 3 3 1 Ankyrin repeats (many copies) CBM_20 PF00686.14 ETO16383.1 - 0.013 15.1 0.2 0.03 13.9 0.1 1.6 1 0 0 1 1 1 0 Starch binding domain Ank_2 PF12796.2 ETO16383.1 - 0.037 14.3 0.0 0.13 12.6 0.0 1.9 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) HSDR_N_2 PF13588.1 ETO16384.1 - 0.15 11.8 1.6 0.37 10.6 1.1 1.6 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Rhabdo_ncap PF00945.13 ETO16385.1 - 0.053 12.1 0.4 0.056 12.0 0.3 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein EF-hand_1 PF00036.27 ETO16386.1 - 1.7e-32 108.2 27.5 2.1e-09 35.9 0.7 4.7 4 1 1 5 5 5 4 EF hand EF-hand_7 PF13499.1 ETO16386.1 - 3.9e-28 97.3 14.9 1.8e-14 53.6 1.7 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 ETO16386.1 - 3.3e-25 86.2 24.0 3.4e-09 35.6 1.1 5.3 4 1 1 5 5 5 4 EF hand EF-hand_6 PF13405.1 ETO16386.1 - 8.4e-24 81.2 20.3 5e-08 32.1 0.4 5.4 4 2 2 6 6 6 4 EF-hand domain EF-hand_8 PF13833.1 ETO16386.1 - 2.7e-22 78.1 26.1 1.1e-14 53.7 4.2 3.9 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.1 ETO16386.1 - 1.7e-12 47.0 0.9 3.9e-05 23.4 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 ETO16386.1 - 1.2e-08 34.9 3.6 0.00031 20.7 0.0 2.4 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 ETO16386.1 - 1e-07 31.6 11.4 0.00039 20.1 0.5 3.2 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 ETO16386.1 - 2.4e-05 23.9 0.2 0.05 13.1 0.0 2.5 2 1 0 2 2 2 2 Caleosin related protein TerB PF05099.8 ETO16386.1 - 0.00038 20.2 9.2 0.031 13.9 0.2 3.2 3 1 0 3 3 3 2 Tellurite resistance protein TerB SR-25 PF10500.4 ETO16386.1 - 0.0054 16.2 9.1 0.008 15.6 6.3 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein EF-hand_10 PF14788.1 ETO16386.1 - 0.01 15.5 5.9 0.033 13.8 0.6 2.6 2 0 0 2 2 2 1 EF hand Med3 PF11593.3 ETO16386.1 - 0.053 12.7 4.2 1.4 8.0 0.5 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Utp21 PF04192.7 ETO16386.1 - 0.06 12.4 4.2 0.076 12.1 2.7 1.4 1 1 0 1 1 1 0 Utp21 specific WD40 associated putative domain DUF1456 PF07308.8 ETO16386.1 - 0.07 13.1 3.8 1.5 8.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) DUF1296 PF06972.6 ETO16386.1 - 0.45 10.5 3.0 1.7 8.6 0.0 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF1296) DUF4629 PF15442.1 ETO16386.1 - 0.51 10.4 10.7 0.81 9.8 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) VCBS PF13517.1 ETO16386.1 - 1.6 9.1 11.8 55 4.2 0.3 4.1 3 1 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella MMR1 PF08505.5 ETO16386.1 - 6 6.8 16.4 3.6 7.5 4.1 2.8 3 0 0 3 3 3 0 Mitochondrial Myo2 receptor-related protein Ribosomal_60s PF00428.14 ETO16386.1 - 9.8 6.6 15.7 1e+02 3.4 8.6 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein Vps52 PF04129.7 ETO16388.1 - 0.01 14.3 3.5 0.012 14.1 2.4 1.0 1 0 0 1 1 1 0 Vps52 / Sac2 family DEK_C PF08766.6 ETO16388.1 - 0.016 14.9 0.1 0.029 14.1 0.1 1.4 1 0 0 1 1 1 0 DEK C terminal domain Transposase_22 PF02994.9 ETO16388.1 - 0.22 9.9 11.5 0.28 9.6 8.0 1.0 1 0 0 1 1 1 0 L1 transposable element Shugoshin_C PF07557.6 ETO16389.1 - 0.02 14.3 1.6 0.02 14.3 1.1 1.6 2 0 0 2 2 2 0 Shugoshin C terminus DUF1673 PF07895.6 ETO16389.1 - 0.074 12.5 0.3 0.11 12.0 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) Zip PF02535.17 ETO16389.1 - 5.2 5.9 5.3 1.6 7.6 1.1 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter TPR_12 PF13424.1 ETO16390.1 - 9.7e-21 73.4 0.5 1.2e-13 50.8 0.0 2.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO16390.1 - 4.8e-14 51.2 4.9 6.6e-06 25.5 0.2 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO16390.1 - 4.4e-12 45.4 10.7 2.8e-05 23.6 0.1 3.1 1 1 2 3 3 3 3 TPR repeat TPR_10 PF13374.1 ETO16390.1 - 1.5e-11 43.8 0.0 7.2e-06 25.7 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO16390.1 - 6.1e-10 38.1 0.1 0.0013 18.3 0.0 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO16390.1 - 6.9e-10 38.0 2.0 0.0015 18.3 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO16390.1 - 1.6e-09 36.8 12.6 4.1e-05 23.0 0.1 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO16390.1 - 4.4e-05 23.3 5.7 0.33 11.2 0.1 3.9 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO16390.1 - 0.0064 17.1 0.0 2.3 8.9 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.13 ETO16390.1 - 0.025 14.4 2.4 2.3 8.1 0.0 3.0 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.1 ETO16390.1 - 0.034 14.0 0.5 2.7 7.9 0.1 2.8 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Mob_Pre PF01076.14 ETO16390.1 - 0.046 13.3 4.7 1.1 8.8 0.4 2.2 2 0 0 2 2 2 0 Plasmid recombination enzyme DUF3856 PF12968.2 ETO16390.1 - 0.078 12.7 0.0 6.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_6 PF13174.1 ETO16390.1 - 0.096 13.1 0.1 21 5.8 0.0 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETO16390.1 - 0.15 12.8 0.0 8.9 7.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat SUKH_5 PF14567.1 ETO16390.1 - 0.18 11.2 1.1 2.4 7.6 0.1 2.1 1 1 1 2 2 2 0 SMI1-KNR4 cell-wall DGF-1_C PF11040.3 ETO16392.1 - 2 8.3 0.0 2 8.3 0.0 2.8 2 1 1 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Hexapep PF00132.19 ETO16393.1 - 0.13 11.7 2.2 0.23 11.0 0.2 2.3 2 0 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) Thiolase_N PF00108.18 ETO16394.1 - 1.4e-60 204.5 8.5 3.9e-48 163.7 0.9 4.0 3 1 1 4 4 4 4 Thiolase, N-terminal domain Thiolase_C PF02803.13 ETO16394.1 - 5e-39 132.5 0.4 5e-39 132.5 0.3 2.3 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 ETO16394.1 - 8.5e-07 28.7 4.1 4.2e-05 23.1 1.0 3.1 3 1 1 4 4 4 2 Beta-ketoacyl synthase, N-terminal domain Ion_trans PF00520.26 ETO16395.1 - 5.5e-45 153.0 20.9 6.1e-34 117.0 11.9 3.7 2 1 0 2 2 2 2 Ion transport protein DctQ PF04290.7 ETO16395.1 - 0.046 13.4 7.3 3.8 7.2 2.5 2.8 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component POLO_box PF00659.13 ETO16396.1 - 1.6e-28 98.4 3.3 3e-15 55.9 0.0 2.5 2 0 0 2 2 2 2 POLO box duplicated region RteC PF09357.5 ETO16396.1 - 0.00041 20.2 0.3 0.00041 20.2 0.2 2.6 2 1 0 2 2 2 1 RteC protein RasGAP PF00616.14 ETO16397.1 - 0.015 14.9 3.6 0.019 14.6 2.5 1.2 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase DUF640 PF04852.7 ETO16397.1 - 0.14 12.3 0.1 0.25 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF640) HD_assoc PF13286.1 ETO16397.1 - 2 8.7 6.4 2.7 8.3 1.1 2.3 1 1 1 2 2 2 0 Phosphohydrolase-associated domain PAP_assoc PF03828.14 ETO16398.1 - 6.6e-10 38.7 0.9 3.1e-09 36.6 0.6 2.1 1 0 0 1 1 1 1 Cid1 family poly A polymerase Pex14_N PF04695.8 ETO16398.1 - 1.3 9.1 11.4 0.054 13.5 2.7 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Tetraspannin PF00335.15 ETO16398.1 - 8.9 5.5 12.0 27 3.9 8.3 1.9 1 1 0 1 1 1 0 Tetraspanin family Cas_CXXC_CXXC PF09706.5 ETO16399.1 - 0.15 12.2 0.8 1.9 8.7 0.1 2.5 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) Fzo_mitofusin PF04799.8 ETO16399.1 - 0.18 11.1 3.3 0.1 12.0 0.2 2.1 2 0 0 2 2 2 0 fzo-like conserved region zf-H2C2_2 PF13465.1 ETO16399.1 - 0.24 11.7 0.3 0.24 11.7 0.2 2.3 3 0 0 3 3 3 0 Zinc-finger double domain zf-Mss51 PF13824.1 ETO16399.1 - 1 9.2 4.2 2.5 8.0 0.0 3.5 4 0 0 4 4 4 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF4208 PF13907.1 ETO16399.1 - 1.9 8.7 8.7 0.5 10.6 0.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4208) DUF87 PF01935.12 ETO16399.1 - 9.4 5.9 11.8 0.47 10.2 1.4 2.9 1 1 1 2 2 2 0 Domain of unknown function DUF87 2OG-FeII_Oxy_2 PF13532.1 ETO16400.1 - 6.1e-08 32.7 0.2 2.1e-07 30.9 0.2 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PWWP PF00855.12 ETO16400.1 - 0.0024 18.0 0.0 0.01 16.0 0.0 2.1 1 0 0 1 1 1 1 PWWP domain Spc7 PF08317.6 ETO16401.1 - 0.0012 17.5 22.5 0.0012 17.5 15.6 1.8 1 1 0 1 1 1 1 Spc7 kinetochore protein TPR_MLP1_2 PF07926.7 ETO16401.1 - 1.7 8.4 33.5 2 8.1 3.5 3.1 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Cob_adeno_trans PF01923.13 ETO16401.1 - 2.1 8.1 9.8 1.9 8.2 5.0 2.1 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DUF4613 PF15390.1 ETO16401.1 - 2.6 6.0 12.7 3.6 5.6 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF848 PF05852.6 ETO16401.1 - 4.9 6.9 19.6 0.31 10.8 7.6 2.7 1 1 1 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) V_ATPase_I PF01496.14 ETO16401.1 - 9.8 3.8 21.9 2.7 5.7 12.6 1.7 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family COG2 PF06148.6 ETO16402.1 - 0.0026 17.6 11.9 0.087 12.6 0.5 2.7 1 1 0 2 2 2 2 COG (conserved oligomeric Golgi) complex component, COG2 Pox_A_type_inc PF04508.7 ETO16402.1 - 0.017 14.8 1.5 0.017 14.8 1.0 3.3 4 0 0 4 4 3 0 Viral A-type inclusion protein repeat IncA PF04156.9 ETO16402.1 - 0.043 13.4 45.8 0.036 13.6 9.0 3.3 1 1 2 3 3 3 0 IncA protein Reo_sigmaC PF04582.7 ETO16402.1 - 0.26 10.4 7.0 0.21 10.6 2.1 2.3 1 1 2 3 3 3 0 Reovirus sigma C capsid protein CCDC-167 PF15188.1 ETO16402.1 - 0.5 10.3 11.6 1.3 9.0 0.6 3.5 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 THOC7 PF05615.8 ETO16402.1 - 0.64 10.2 38.0 1.6 8.9 10.2 3.5 1 1 2 3 3 3 0 Tho complex subunit 7 DUF730 PF05325.6 ETO16402.1 - 2.2 8.0 5.6 8.8 6.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF730) Fzo_mitofusin PF04799.8 ETO16402.1 - 2.6 7.4 28.7 3.5 6.9 5.9 2.6 1 1 1 2 2 2 0 fzo-like conserved region CENP-F_leu_zip PF10473.4 ETO16402.1 - 2.8 7.8 41.0 1.4 8.7 11.2 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 ETO16402.1 - 3.2 6.9 42.9 2.1 7.5 23.4 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding MutS_IV PF05190.13 ETO16402.1 - 3.6 7.8 19.6 3.4 7.9 1.0 4.2 2 1 2 4 4 4 0 MutS family domain IV AAA_13 PF13166.1 ETO16402.1 - 6.1 5.1 38.1 0.045 12.2 19.7 2.1 3 0 0 3 3 3 0 AAA domain WD40 PF00400.27 ETO16405.1 - 3.9e-12 45.5 0.8 1.4e-05 24.7 0.1 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat WD40 PF00400.27 ETO16406.1 - 6.8e-15 54.3 3.1 1.2e-08 34.4 0.1 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat NAF PF03822.9 ETO16406.1 - 0.077 12.7 0.3 15 5.3 0.0 2.6 2 0 0 2 2 2 0 NAF domain FliJ PF02050.11 ETO16407.1 - 0.0017 18.3 0.4 0.003 17.6 0.3 1.3 1 0 0 1 1 1 1 Flagellar FliJ protein DUF2935 PF11155.3 ETO16407.1 - 0.018 15.1 1.6 0.022 14.8 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) Mnd1 PF03962.10 ETO16407.1 - 0.019 14.6 2.5 0.021 14.5 1.7 1.1 1 0 0 1 1 1 0 Mnd1 family DUF4200 PF13863.1 ETO16407.1 - 0.019 14.8 2.0 0.028 14.3 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF334 PF03904.8 ETO16407.1 - 0.035 13.4 0.8 0.045 13.0 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Rabaptin PF03528.10 ETO16407.1 - 0.038 13.9 0.4 0.071 13.0 0.2 1.4 1 1 0 1 1 1 0 Rabaptin Spc7 PF08317.6 ETO16407.1 - 0.04 12.5 4.8 0.048 12.3 3.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Resolvase PF00239.16 ETO16407.1 - 0.097 12.5 0.2 0.12 12.2 0.2 1.1 1 0 0 1 1 1 0 Resolvase, N terminal domain V_ATPase_I PF01496.14 ETO16407.1 - 0.1 10.4 1.5 0.13 10.1 1.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cortex-I_coil PF09304.5 ETO16407.1 - 0.12 12.4 4.8 0.16 12.0 3.3 1.1 1 0 0 1 1 1 0 Cortexillin I, coiled coil DUF4356 PF14266.1 ETO16407.1 - 0.13 10.6 2.2 0.15 10.4 1.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4356) Reo_sigmaC PF04582.7 ETO16407.1 - 0.15 11.1 4.1 0.19 10.9 2.9 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TBPIP PF07106.8 ETO16407.1 - 0.19 11.2 5.8 1.2 8.6 4.1 1.9 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GAS PF13851.1 ETO16407.1 - 0.29 10.3 6.5 0.54 9.4 0.2 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.4 ETO16407.1 - 0.29 11.3 6.6 0.55 10.3 1.9 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3450 PF11932.3 ETO16407.1 - 0.34 10.1 3.8 0.77 8.9 1.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Vps51 PF08700.6 ETO16407.1 - 0.37 10.6 3.3 1.8 8.4 0.1 2.2 1 1 1 2 2 2 0 Vps51/Vps67 Fib_alpha PF08702.5 ETO16407.1 - 0.54 10.3 6.5 1.4 9.0 4.5 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family YlbD_coat PF14071.1 ETO16407.1 - 1.6 8.7 4.4 2.6 8.1 3.1 1.3 1 0 0 1 1 1 0 Putative coat protein Bap31 PF05529.7 ETO16407.1 - 2.2 7.7 5.8 3.1 7.1 4.0 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Sad1_UNC PF07738.8 ETO16408.1 - 2.6e-10 40.2 0.1 8.2e-10 38.5 0.0 1.9 2 1 0 2 2 2 1 Sad1 / UNC-like C-terminal Tropomyosin_1 PF12718.2 ETO16408.1 - 0.00025 20.8 5.8 0.00025 20.8 4.0 1.8 2 0 0 2 2 2 1 Tropomyosin like DUF241 PF03087.9 ETO16408.1 - 0.03 13.7 4.4 0.058 12.8 3.0 1.5 1 1 0 1 1 1 0 Arabidopsis protein of unknown function Herpes_UL6 PF01763.11 ETO16408.1 - 0.063 11.4 5.2 0.074 11.2 3.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Transposase_22 PF02994.9 ETO16408.1 - 0.075 11.5 6.1 0.094 11.1 4.2 1.1 1 0 0 1 1 1 0 L1 transposable element V_ATPase_I PF01496.14 ETO16408.1 - 0.15 9.8 3.2 0.17 9.6 2.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YlbD_coat PF14071.1 ETO16408.1 - 0.2 11.7 9.1 6 6.9 3.6 3.0 2 1 1 3 3 3 0 Putative coat protein IncA PF04156.9 ETO16408.1 - 0.88 9.1 8.2 1.1 8.7 5.5 1.4 1 1 0 1 1 1 0 IncA protein DUF972 PF06156.8 ETO16408.1 - 1.2 9.5 9.6 0.53 10.6 3.6 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF972) APG6 PF04111.7 ETO16408.1 - 1.2 8.0 9.8 1.7 7.6 6.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 EMP24_GP25L PF01105.19 ETO16408.1 - 1.9 8.1 9.7 3.5 7.2 0.2 2.2 1 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Fib_alpha PF08702.5 ETO16408.1 - 2.4 8.2 9.5 5.5 7.1 6.5 1.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Mnd1 PF03962.10 ETO16408.1 - 2.6 7.6 10.6 1.3 8.6 4.4 2.0 1 1 1 2 2 2 0 Mnd1 family Allexi_40kDa PF05549.6 ETO16408.1 - 5.7 6.1 9.7 3.3 6.9 2.9 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein Vac_Fusion PF02346.11 ETO16408.1 - 6.3 6.3 6.3 0.87 9.0 0.8 2.2 3 0 0 3 3 3 0 Chordopoxvirus fusion protein DUF16 PF01519.11 ETO16408.1 - 9.3 6.5 10.0 1.4e+02 2.7 6.8 2.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 BRO1 PF03097.13 ETO16409.1 - 6.2e-20 71.2 2.3 9.5e-20 70.6 1.6 1.3 1 1 0 1 1 1 1 BRO1-like domain Hira PF07569.6 ETO16412.1 - 4.1e-13 49.0 2.6 9.3e-13 47.8 1.8 1.6 1 0 0 1 1 1 1 TUP1-like enhancer of split DUF4131 PF13567.1 ETO16412.1 - 0.0097 15.3 0.1 0.016 14.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) Methyltransf_31 PF13847.1 ETO16413.1 - 2.6e-19 69.3 0.0 3.7e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETO16413.1 - 4.4e-18 65.5 0.0 7e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO16413.1 - 1.7e-16 60.7 0.0 3.3e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETO16413.1 - 2e-16 60.2 0.0 5.2e-16 58.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 ETO16413.1 - 9e-14 51.2 0.0 2e-13 50.0 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 ETO16413.1 - 5e-12 46.1 0.0 1.7e-11 44.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETO16413.1 - 5.5e-11 42.7 0.0 1.3e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETO16413.1 - 7e-10 38.4 0.0 2.4e-09 36.6 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 ETO16413.1 - 9.1e-10 38.5 0.0 2.4e-09 37.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 ETO16413.1 - 3.6e-08 33.2 0.0 6.2e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 ETO16413.1 - 3.7e-07 29.6 0.0 8.7e-07 28.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 ETO16413.1 - 3.1e-06 26.8 0.0 4.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase FmrO PF07091.6 ETO16413.1 - 6e-05 22.1 0.0 0.00011 21.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) PrmA PF06325.8 ETO16413.1 - 0.00019 20.6 0.0 0.00033 19.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 ETO16413.1 - 0.0002 20.8 0.0 0.00066 19.1 0.0 1.8 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 ETO16413.1 - 0.00034 20.3 0.0 0.00072 19.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 ETO16413.1 - 0.0017 17.7 0.0 0.003 16.8 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_9 PF08003.6 ETO16413.1 - 0.0017 17.1 0.0 0.0029 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CheR PF01739.13 ETO16413.1 - 0.0017 17.6 0.1 0.16 11.2 0.0 2.8 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain TehB PF03848.9 ETO16413.1 - 0.0053 15.9 0.0 0.0084 15.2 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB TPMT PF05724.6 ETO16413.1 - 0.0058 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_3 PF01596.12 ETO16413.1 - 0.012 14.6 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_4 PF02390.12 ETO16413.1 - 0.018 14.1 0.0 0.081 11.9 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_2 PF00891.13 ETO16413.1 - 0.022 13.9 0.0 0.074 12.2 0.0 1.8 1 1 0 1 1 1 0 O-methyltransferase UPF0020 PF01170.13 ETO16413.1 - 0.023 14.2 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 WD40 PF00400.27 ETO16414.1 - 1.1e-61 202.5 5.9 7.6e-13 47.7 0.1 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO16414.1 - 3.7e-10 39.8 3.2 0.00025 20.8 0.1 3.0 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO16414.1 - 3.1e-07 29.8 1.6 1.8 8.3 0.1 6.1 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO16414.1 - 7.7e-07 27.6 1.1 0.13 10.3 0.0 3.7 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO16414.1 - 0.00043 18.7 0.2 0.0071 14.6 0.0 2.3 1 1 0 2 2 2 1 Cytochrome D1 heme domain DUF1258 PF06869.7 ETO16414.1 - 0.0014 17.8 2.7 0.41 9.6 0.1 3.0 2 1 0 3 3 3 2 Protein of unknown function (DUF1258) Hira PF07569.6 ETO16414.1 - 0.0072 15.5 1.5 5.2 6.2 0.0 3.8 1 1 2 4 4 4 1 TUP1-like enhancer of split PQQ_2 PF13360.1 ETO16414.1 - 0.013 14.9 0.0 0.079 12.4 0.0 2.1 1 1 0 1 1 1 0 PQQ-like domain Resistin PF06954.6 ETO16414.1 - 0.12 12.6 2.1 5.1 7.4 0.1 3.2 2 2 1 3 3 3 0 Resistin Proteasome_A_N PF10584.4 ETO16414.1 - 9.4 5.6 6.0 38 3.7 0.1 3.9 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature DUF4423 PF14394.1 ETO16415.1 - 0.0017 17.9 0.4 0.0029 17.1 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) DUF4509 PF14970.1 ETO16415.1 - 0.052 13.2 0.7 0.072 12.7 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) Ribosomal_S9 PF00380.14 ETO16415.1 - 0.11 12.7 0.2 0.36 11.0 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein S9/S16 IncA PF04156.9 ETO16415.1 - 0.16 11.5 2.2 0.3 10.6 1.5 1.4 1 0 0 1 1 1 0 IncA protein PhyH PF05721.8 ETO16416.1 - 1.6e-16 61.0 0.0 2.7e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DLH PF01738.13 ETO16417.1 - 4.4e-14 52.3 0.0 1.8e-13 50.2 0.0 1.9 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 ETO16417.1 - 0.0013 18.5 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family BRF1 PF07741.8 ETO16417.1 - 0.017 15.3 0.0 0.028 14.6 0.0 1.4 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Exo_endo_phos_2 PF14529.1 ETO16419.1 - 4.9e-18 64.8 0.2 1.2e-17 63.6 0.1 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF2877 PF11392.3 ETO16420.1 - 0.044 13.9 0.1 0.083 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2877) SPRY PF00622.23 ETO16421.1 - 1.3e-20 73.7 4.5 1.5e-10 41.2 0.6 2.6 2 0 0 2 2 2 2 SPRY domain Sad1_UNC PF07738.8 ETO16421.1 - 0.011 15.5 1.4 0.74 9.6 1.0 2.7 1 1 0 1 1 1 0 Sad1 / UNC-like C-terminal Bunya_NS-S PF01104.12 ETO16421.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Bunyavirus non-structural protein NS-s Mcp5_PH PF12814.2 ETO16422.1 - 0.061 13.2 0.4 0.061 13.2 0.3 3.1 3 1 0 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology CAF-1_p150 PF11600.3 ETO16422.1 - 4.1 6.7 48.0 1.9 7.7 5.0 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal GATase PF00117.23 ETO16423.1 - 4.4e-21 75.2 0.0 7.9e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 ETO16423.1 - 7.5e-20 70.7 0.0 3.8e-19 68.4 0.0 2.0 2 1 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.8 ETO16423.1 - 0.0068 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase C26 GATase PF00117.23 ETO16424.1 - 4.3e-17 62.2 0.0 5.4e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I ERM PF00769.14 ETO16425.1 - 0.065 12.7 88.0 0.77 9.2 12.5 4.5 2 2 2 4 4 4 0 Ezrin/radixin/moesin family Kelch_6 PF13964.1 ETO16427.1 - 0.017 15.3 0.7 0.61 10.3 0.0 3.0 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.1 ETO16427.1 - 0.083 12.8 0.1 20 5.2 0.0 2.8 3 0 0 3 3 3 0 Kelch motif Ras PF00071.17 ETO16428.1 - 2.6e-08 33.4 0.0 3.9e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Ras family WD40 PF00400.27 ETO16429.1 - 0.00016 21.4 0.0 0.00062 19.5 0.0 2.1 2 0 0 2 2 2 1 WD domain, G-beta repeat TLD PF07534.11 ETO16430.1 - 2.4e-08 34.0 3.6 2.9e-08 33.7 0.1 2.8 3 0 0 3 3 3 1 TLD Geminin PF07412.7 ETO16431.1 - 0.00012 21.8 4.6 0.00021 21.0 3.2 1.4 1 0 0 1 1 1 1 Geminin Sec2p PF06428.6 ETO16431.1 - 0.0013 18.5 5.2 0.0013 18.5 3.6 1.5 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DivIC PF04977.10 ETO16431.1 - 0.003 17.0 3.7 0.003 17.0 2.6 2.4 2 1 1 3 3 3 2 Septum formation initiator P2_Phage_GpR PF06891.6 ETO16431.1 - 0.0067 16.2 0.4 0.041 13.6 0.0 1.9 2 0 0 2 2 2 1 P2 phage tail completion protein R (GpR) KIAA1430 PF13879.1 ETO16431.1 - 0.014 15.7 0.4 0.014 15.7 0.3 2.2 1 1 1 2 2 2 0 KIAA1430 homologue HALZ PF02183.13 ETO16431.1 - 0.018 14.7 6.4 0.42 10.3 0.6 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF4446 PF14584.1 ETO16431.1 - 0.052 13.3 1.0 0.072 12.9 0.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) RIC3 PF15361.1 ETO16431.1 - 0.47 10.6 3.7 0.6 10.3 2.3 1.5 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF2681 PF10883.3 ETO16431.1 - 0.64 10.2 9.9 0.25 11.5 4.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) DUF837 PF05769.6 ETO16431.1 - 0.69 9.4 11.7 0.16 11.4 5.3 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF837) TSC22 PF01166.13 ETO16431.1 - 0.76 9.7 11.5 3.1 7.8 0.7 3.0 2 1 1 3 3 3 0 TSC-22/dip/bun family Med9 PF07544.8 ETO16431.1 - 1.6 8.4 7.0 0.28 10.9 2.3 1.7 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 bZIP_2 PF07716.10 ETO16431.1 - 2 8.3 12.7 1.5 8.6 1.3 2.7 3 0 0 3 3 3 0 Basic region leucine zipper RraB PF06877.6 ETO16431.1 - 2.3 8.9 5.1 4.9 7.8 3.4 1.7 1 1 0 1 1 1 0 Regulator of ribonuclease activity B DUF1510 PF07423.6 ETO16433.1 - 0.00051 19.4 9.0 0.00051 19.4 6.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) SDA1 PF05285.7 ETO16433.1 - 0.0048 16.2 14.9 0.0049 16.1 10.3 1.0 1 0 0 1 1 1 1 SDA1 PBP_sp32 PF07222.7 ETO16433.1 - 0.021 13.9 7.0 0.022 13.9 4.8 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 RR_TM4-6 PF06459.7 ETO16433.1 - 0.023 14.5 13.2 0.026 14.4 9.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Herpes_DNAp_acc PF04929.7 ETO16433.1 - 0.32 9.9 7.8 0.37 9.7 5.4 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Ycf1 PF05758.7 ETO16433.1 - 0.61 7.7 10.8 0.56 7.8 7.5 1.0 1 0 0 1 1 1 0 Ycf1 GAGA_bind PF06217.7 ETO16433.1 - 0.68 9.8 8.1 0.63 9.9 5.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DDHD PF02862.12 ETO16433.1 - 0.92 9.2 8.5 0.86 9.3 5.9 1.2 1 0 0 1 1 1 0 DDHD domain RNase_H2-Ydr279 PF09468.5 ETO16433.1 - 1.1 8.3 11.7 1.3 8.1 8.1 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) CDC45 PF02724.9 ETO16433.1 - 1.6 6.6 12.4 1.7 6.6 8.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.3 ETO16433.1 - 1.8 7.0 10.9 2 6.9 7.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Hid1 PF12722.2 ETO16433.1 - 2.3 5.7 6.5 2.1 5.9 4.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AIF_C PF14721.1 ETO16433.1 - 3.2 7.9 11.0 4.7 7.4 7.6 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term TAF4 PF05236.9 ETO16433.1 - 3.4 6.8 25.6 85 2.2 18.9 1.9 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family RNA_polI_A34 PF08208.6 ETO16433.1 - 3.6 7.2 23.6 5 6.7 16.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Tom37_C PF11801.3 ETO16433.1 - 4.2 7.2 10.0 5.7 6.7 7.0 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain Presenilin PF01080.12 ETO16433.1 - 5 5.8 5.9 6.1 5.5 4.1 1.1 1 0 0 1 1 1 0 Presenilin NARP1 PF12569.3 ETO16433.1 - 6 5.4 16.2 6.9 5.2 11.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Usp PF00582.21 ETO16433.1 - 6.1 7.0 6.8 8.4 6.5 4.7 1.2 1 0 0 1 1 1 0 Universal stress protein family Serinc PF03348.10 ETO16433.1 - 7.4 5.1 6.6 8.8 4.9 4.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) EAP30 PF04157.11 ETO16434.1 - 3.3e-05 23.1 13.2 3.3e-05 23.1 9.2 2.0 1 1 1 2 2 2 1 EAP30/Vps36 family DUF3080 PF11279.3 ETO16434.1 - 0.04 13.0 13.7 0.049 12.7 9.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) UPF0181 PF03701.9 ETO16434.1 - 0.09 12.0 0.0 0.09 12.0 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0181) FUSC PF04632.7 ETO16434.1 - 0.14 10.5 1.3 0.17 10.3 0.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4618 PF15397.1 ETO16434.1 - 0.26 10.5 29.0 0.36 10.1 20.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Globin PF00042.17 ETO16434.1 - 0.62 10.4 7.1 0.6 10.4 0.8 2.6 1 1 2 3 3 3 0 Globin Pox_A_type_inc PF04508.7 ETO16434.1 - 0.87 9.5 0.0 0.87 9.5 0.0 4.8 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat DUF2854 PF11016.3 ETO16434.1 - 1.2 8.6 8.2 1.2 8.6 4.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2854) DUF4163 PF13739.1 ETO16434.1 - 2.6 8.8 14.5 0.48 11.2 0.6 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4163) Exonuc_VII_L PF02601.10 ETO16434.1 - 3 6.9 20.8 4.7 6.3 14.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.4 ETO16434.1 - 3.7 6.4 30.7 2.4 7.0 1.5 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Spectrin PF00435.16 ETO16434.1 - 7.2 6.9 27.0 0.85 9.9 10.0 2.2 1 1 1 2 2 2 0 Spectrin repeat DUF4200 PF13863.1 ETO16434.1 - 8.8 6.2 36.4 0.13 12.1 6.3 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) Baculo_p24 PF05073.7 ETO16434.1 - 9 5.8 16.2 3.6 7.1 9.2 1.8 1 1 0 1 1 1 0 Baculovirus P24 capsid protein Rootletin PF15035.1 ETO16435.1 - 0.0023 17.9 29.9 0.0038 17.2 7.3 2.9 1 1 1 2 2 2 1 Ciliary rootlet component, centrosome cohesion XhlA PF10779.4 ETO16435.1 - 0.017 14.9 1.2 0.017 14.9 0.8 3.4 3 1 0 3 3 3 0 Haemolysin XhlA FHIPEP PF00771.15 ETO16435.1 - 0.03 12.6 3.1 0.03 12.6 2.2 1.1 1 0 0 1 1 1 0 FHIPEP family TelA PF05816.6 ETO16435.1 - 0.043 12.5 13.4 0.013 14.2 7.2 1.5 1 1 0 1 1 1 0 Toxic anion resistance protein (TelA) Glu-tRNAGln PF02686.10 ETO16435.1 - 0.052 13.3 0.7 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit Atg14 PF10186.4 ETO16435.1 - 0.073 12.0 22.3 0.25 10.2 15.4 1.8 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Reo_sigmaC PF04582.7 ETO16435.1 - 0.19 10.8 3.2 0.22 10.6 1.2 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 ETO16435.1 - 0.33 10.7 29.7 0.016 15.0 14.5 2.0 1 1 1 2 2 2 0 Tropomyosin like Uso1_p115_C PF04871.8 ETO16435.1 - 0.45 10.4 23.1 0.2 11.5 6.6 3.0 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region WEMBL PF05701.6 ETO16435.1 - 0.66 8.3 21.7 1.1e+02 1.0 3.5 1.8 1 1 0 1 1 1 0 Weak chloroplast movement under blue light HrpB7 PF09486.5 ETO16435.1 - 0.71 9.7 9.5 0.47 10.3 1.0 2.5 2 1 1 3 3 2 0 Bacterial type III secretion protein (HrpB7) PEARLI-4 PF05278.7 ETO16435.1 - 0.94 8.7 12.1 0.11 11.8 4.9 1.9 1 1 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF4200 PF13863.1 ETO16435.1 - 0.98 9.3 23.5 0.72 9.8 5.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) DUF1664 PF07889.7 ETO16435.1 - 1 9.1 10.8 0.43 10.3 4.7 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF4407 PF14362.1 ETO16435.1 - 1.1 8.1 9.0 1.3 7.9 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Rho_Binding PF08912.6 ETO16435.1 - 1.4 9.2 24.6 0.22 11.8 3.7 3.3 2 1 1 3 3 3 0 Rho Binding ERM PF00769.14 ETO16435.1 - 1.5 8.3 24.4 6.1 6.3 16.8 1.9 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF4446 PF14584.1 ETO16435.1 - 1.5 8.5 11.1 1.1 9.0 2.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) DUF4600 PF15372.1 ETO16435.1 - 1.7 8.8 23.5 0.099 12.8 9.7 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4600) DUF4164 PF13747.1 ETO16435.1 - 1.7 8.7 17.2 0.9 9.7 3.4 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Spc7 PF08317.6 ETO16435.1 - 2.3 6.8 20.7 0.22 10.1 10.7 1.7 1 1 0 2 2 2 0 Spc7 kinetochore protein DUF4201 PF13870.1 ETO16435.1 - 2.6 7.4 25.2 1.5 8.2 4.8 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) CENP-F_leu_zip PF10473.4 ETO16435.1 - 2.6 7.8 30.7 0.26 11.1 14.8 2.4 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SecD-TM1 PF13721.1 ETO16435.1 - 3.1 8.0 6.2 0.33 11.2 0.7 2.1 2 1 1 3 3 2 0 SecD export protein N-terminal TM region LXG PF04740.7 ETO16435.1 - 3.3 7.4 14.2 8 6.1 9.5 1.9 1 1 0 1 1 1 0 LXG domain of WXG superfamily SlyX PF04102.7 ETO16435.1 - 3.4 8.0 20.6 1.1 9.6 2.3 3.8 2 1 2 4 4 4 0 SlyX ADIP PF11559.3 ETO16435.1 - 3.7 7.4 30.0 0.08 12.8 7.3 2.8 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Laminin_II PF06009.7 ETO16435.1 - 3.8 7.2 16.8 0.41 10.4 3.2 2.7 1 1 1 3 3 3 0 Laminin Domain II DUF641 PF04859.7 ETO16435.1 - 4.5 7.0 13.4 0.89 9.3 5.7 2.4 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF972 PF06156.8 ETO16435.1 - 4.7 7.5 23.1 3.2 8.1 4.2 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DUF342 PF03961.8 ETO16435.1 - 5.4 5.3 14.3 1.2 7.4 7.6 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Vps51 PF08700.6 ETO16435.1 - 5.9 6.7 11.6 2.2 8.1 0.3 3.4 3 1 0 3 3 3 0 Vps51/Vps67 CENP-O PF09496.5 ETO16435.1 - 5.9 7.1 7.1 48 4.2 0.4 3.1 3 0 0 3 3 3 0 Cenp-O kinetochore centromere component Enkurin PF13864.1 ETO16435.1 - 6.3 7.0 20.3 22 5.3 5.5 2.8 1 1 1 2 2 2 0 Calmodulin-binding TMF_DNA_bd PF12329.3 ETO16435.1 - 7 6.5 28.3 1.7 8.4 2.7 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF2968 PF11180.3 ETO16435.1 - 7.3 5.9 18.4 0.21 10.9 3.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) NPV_P10 PF05531.7 ETO16435.1 - 8.2 6.7 11.3 47 4.3 4.7 3.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2203 PF09969.4 ETO16435.1 - 9.2 6.5 8.5 7.3 6.8 0.7 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Phage_int_SAM_1 PF02899.12 ETO16436.1 - 0.078 13.1 3.4 4.4 7.5 0.1 3.1 3 1 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain DUF1048 PF06304.6 ETO16436.1 - 0.18 12.0 6.8 0.28 11.4 0.2 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1048) DUF3407 PF11887.3 ETO16436.1 - 0.23 10.7 4.6 0.97 8.6 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3407) HALZ PF02183.13 ETO16436.1 - 0.99 9.1 14.6 1.4 8.6 1.5 4.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF3584 PF12128.3 ETO16436.1 - 2.2 5.5 38.2 1.7 5.8 10.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) RBFA PF02033.13 ETO16436.1 - 2.9 7.9 8.6 9.5 6.3 0.5 3.2 3 0 0 3 3 3 0 Ribosome-binding factor A ATG16 PF08614.6 ETO16436.1 - 6.2 6.5 48.9 0.61 9.8 17.6 3.1 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Metallophos PF00149.23 ETO16437.1 - 2e-22 79.5 0.1 3e-22 79.0 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase WWE PF02825.15 ETO16438.1 - 0.00012 21.4 0.1 0.00042 19.6 0.1 2.0 1 1 0 1 1 1 1 WWE domain POX PF07526.6 ETO16438.1 - 0.033 14.4 1.7 0.033 14.4 1.2 2.2 3 0 0 3 3 3 0 Associated with HOX EF-hand_1 PF00036.27 ETO16439.1 - 0.00045 19.3 0.7 0.00045 19.3 0.5 2.0 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 ETO16439.1 - 0.0018 18.3 0.4 0.0089 16.1 0.0 2.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO16439.1 - 0.0064 16.2 0.4 0.029 14.2 0.3 2.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 ETO16439.1 - 0.022 14.1 0.6 0.079 12.3 0.4 2.1 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.1 ETO16439.1 - 0.036 13.6 0.6 0.085 12.4 0.4 1.6 1 0 0 1 1 1 0 EF-hand domain pair DUF2702 PF10863.3 ETO16441.1 - 0.021 14.5 0.6 0.055 13.1 0.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2702) DUF2428 PF10350.4 ETO16442.1 - 3.6e-13 49.1 0.0 6.1e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) DUF2428 PF10350.4 ETO16443.1 - 6.6e-22 77.7 0.1 1e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) H_PPase PF03030.11 ETO16444.1 - 1e-82 278.4 19.2 2.1e-48 165.1 1.4 2.0 2 0 0 2 2 2 2 Inorganic H+ pyrophosphatase Kinesin PF00225.18 ETO16446.1 - 1.3e-06 27.3 1.6 3.9e-05 22.5 1.1 2.7 1 1 0 1 1 1 1 Kinesin motor domain ABC2_membrane_4 PF12730.2 ETO16447.1 - 4.5 6.3 17.2 0.69 9.0 7.8 2.4 1 1 1 2 2 2 0 ABC-2 family transporter protein PMSR PF01625.16 ETO16448.1 - 1.3e-21 77.1 9.3 1.6e-21 76.7 6.4 1.3 1 1 0 1 1 1 1 Peptide methionine sulfoxide reductase CRA_rpt PF07046.6 ETO16448.1 - 0.094 12.7 6.0 0.19 11.7 4.2 1.4 1 0 0 1 1 1 0 Cytoplasmic repetitive antigen (CRA) like repeat Ldl_recept_a PF00057.13 ETO16448.1 - 0.14 12.1 0.9 0.24 11.3 0.1 1.8 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A EF-hand_1 PF00036.27 ETO16449.1 - 9e-10 37.1 0.3 4.4e-08 31.8 0.1 3.3 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.1 ETO16449.1 - 5e-09 36.1 2.3 5e-08 32.9 0.1 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO16449.1 - 9.4e-09 34.4 0.1 2.9e-06 26.6 0.1 3.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 ETO16449.1 - 7.7e-07 28.1 0.1 2e-06 26.8 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 ETO16449.1 - 0.00045 19.7 0.4 0.0028 17.2 0.0 2.5 2 1 0 2 2 2 1 EF-hand domain pair DUF2100 PF09873.4 ETO16449.1 - 0.058 12.8 0.1 0.084 12.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2100) 3H PF02829.9 ETO16450.1 - 0.19 11.7 1.8 0.72 9.9 0.0 2.8 3 0 0 3 3 3 0 3H domain Rtt102p PF09510.5 ETO16451.1 - 0.01 15.8 2.8 0.017 15.0 1.9 1.3 1 0 0 1 1 1 0 Rtt102p-like transcription regulator protein SID-1_RNA_chan PF13965.1 ETO16451.1 - 0.14 10.3 4.9 0.16 10.1 3.4 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CLAMP PF14769.1 ETO16451.1 - 0.21 11.7 1.2 0.88 9.7 0.2 2.2 2 0 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 CCDC155 PF14662.1 ETO16451.1 - 0.23 11.0 4.0 0.36 10.4 0.7 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 RVT_1 PF00078.22 ETO16453.1 - 2.9e-14 52.9 0.3 6.4e-14 51.8 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Arm PF00514.18 ETO16456.1 - 2.5e-21 74.6 0.4 7.1e-06 25.6 0.0 4.7 5 0 0 5 5 5 4 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 ETO16456.1 - 8.5e-07 29.2 0.0 0.012 16.0 0.0 2.7 2 1 0 2 2 2 2 HEAT-like repeat HEAT_2 PF13646.1 ETO16456.1 - 0.0004 20.6 0.0 0.65 10.3 0.0 2.2 1 1 1 2 2 2 2 HEAT repeats RICTOR_V PF14668.1 ETO16456.1 - 0.13 12.2 0.0 9.1 6.3 0.0 2.9 1 1 2 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 DUF739 PF05339.6 ETO16458.1 - 0.076 12.8 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF739) FpoO PF10621.4 ETO16458.1 - 1.5 8.8 6.5 0.23 11.5 0.8 2.1 1 1 1 2 2 2 0 F420H2 dehydrogenase subunit FpoO Bromodomain PF00439.20 ETO16459.1 - 3.2e-25 87.8 0.0 4.7e-25 87.3 0.0 1.3 1 1 0 1 1 1 1 Bromodomain DUF4274 PF14096.1 ETO16460.1 - 0.053 13.3 0.3 0.059 13.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4274) DUF3682 PF12446.3 ETO16460.1 - 0.099 12.9 8.7 0.1 12.9 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Nucleoplasmin PF03066.10 ETO16460.1 - 0.48 9.9 6.8 0.48 9.9 4.7 1.1 1 0 0 1 1 1 0 Nucleoplasmin DUF4044 PF13253.1 ETO16460.1 - 0.53 9.4 0.3 0.53 9.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4044) Sporozoite_P67 PF05642.6 ETO16460.1 - 3.3 5.4 6.3 3 5.6 4.3 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RNase_H2-Ydr279 PF09468.5 ETO16460.1 - 4.8 6.2 9.1 4.5 6.3 6.3 1.0 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF3451 PF11933.3 ETO16460.1 - 5.5 6.7 8.7 5.7 6.6 6.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3451) YqfQ PF14181.1 ETO16460.1 - 6.2 6.8 8.6 6.4 6.7 6.0 1.0 1 0 0 1 1 1 0 YqfQ-like protein Ras PF00071.17 ETO16462.1 - 7.4e-17 61.2 1.7 1.2e-15 57.2 1.2 2.2 1 1 0 1 1 1 1 Ras family Miro PF08477.8 ETO16462.1 - 2.2e-06 28.1 0.0 5.7e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein RIO1 PF01163.17 ETO16462.1 - 0.022 14.0 1.5 0.022 14.0 0.1 1.6 2 0 0 2 2 2 0 RIO1 family EamA PF00892.15 ETO16462.1 - 2.5 8.1 9.8 2.3 8.2 3.6 2.5 2 0 0 2 2 2 0 EamA-like transporter family TspO_MBR PF03073.10 ETO16462.1 - 3.2 7.2 12.1 0.077 12.5 0.9 2.8 3 0 0 3 3 3 0 TspO/MBR family BLOC1_2 PF10046.4 ETO16463.1 - 0.021 14.9 2.3 0.021 14.9 1.6 2.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SAM_2 PF07647.12 ETO16463.1 - 0.044 13.6 0.0 0.097 12.5 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) RabGAP-TBC PF00566.13 ETO16464.1 - 6.5e-20 71.5 8.9 5.9e-19 68.3 6.2 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.20 ETO16465.1 - 1.4e-10 40.7 0.0 2.7e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Cyclin PF08613.6 ETO16466.1 - 9.7e-09 35.7 0.0 1.7e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 ETO16466.1 - 1.4e-05 24.6 0.1 3e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Scs3p PF10261.4 ETO16466.1 - 0.089 11.8 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM DUF912 PF06024.7 ETO16466.1 - 0.79 9.8 8.3 0.068 13.2 2.1 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) EVI2A PF05399.6 ETO16466.1 - 2.7 7.1 8.5 0.038 13.2 0.9 1.6 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) Acyltransferase PF01553.16 ETO16467.1 - 0.00076 18.9 0.0 0.0022 17.3 0.0 1.9 1 1 0 1 1 1 1 Acyltransferase Nop PF01798.13 ETO16468.1 - 2.2e-36 124.4 0.2 3.4e-36 123.7 0.2 1.3 1 0 0 1 1 1 1 Putative snoRNA binding domain Prp31_C PF09785.4 ETO16468.1 - 1.4e-17 64.2 7.8 6.8e-17 62.0 5.4 2.0 1 1 0 1 1 1 1 Prp31 C terminal domain NOSIC PF08060.8 ETO16469.1 - 7e-17 60.9 0.5 1.1e-16 60.3 0.3 1.3 1 0 0 1 1 1 1 NOSIC (NUC001) domain FGF-BP1 PF06473.7 ETO16469.1 - 0.13 11.8 3.0 0.18 11.3 2.1 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) RGS PF00615.14 ETO16470.1 - 3.9e-06 26.9 0.2 6.2e-06 26.2 0.1 1.4 1 1 0 1 1 1 1 Regulator of G protein signaling domain DUF357 PF04010.8 ETO16471.1 - 0.094 12.4 0.2 0.36 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF357) Zip PF02535.17 ETO16471.1 - 4.7 6.1 6.7 8.2 5.3 4.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter SAM_1 PF00536.25 ETO16473.1 - 3e-13 49.7 0.4 5e-13 49.0 0.2 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO16473.1 - 1.1e-12 47.5 0.2 1.9e-12 46.8 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 ETO16473.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Pkinase PF00069.20 ETO16475.1 - 4.4e-37 127.6 0.2 1.1e-36 126.3 0.2 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO16475.1 - 4.7e-16 58.6 0.5 1.1e-15 57.4 0.3 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO16475.1 - 0.004 16.2 0.1 0.0075 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 ETO16475.1 - 0.0061 15.9 0.1 0.012 15.0 0.1 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 ETO16475.1 - 0.04 13.6 0.0 0.092 12.4 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family FlaC_arch PF05377.6 ETO16476.1 - 0.007 16.2 0.2 0.007 16.2 0.1 9.8 9 2 3 12 12 12 2 Flagella accessory protein C (FlaC) DUF641 PF04859.7 ETO16477.1 - 0.0087 15.8 3.4 0.0087 15.8 2.4 2.0 2 0 0 2 2 2 1 Plant protein of unknown function (DUF641) zf-C4H2 PF10146.4 ETO16477.1 - 1.6 8.6 14.9 2.2 8.2 10.2 1.3 1 1 0 1 1 1 0 Zinc finger-containing protein ASD2 PF08687.6 ETO16477.1 - 2.2 7.5 17.0 0.088 12.1 5.5 2.1 1 1 1 2 2 2 0 Apx/Shroom domain ASD2 RNA_pol_3_Rpc31 PF11705.3 ETO16477.1 - 6.2 6.6 22.4 1.4 8.8 12.1 1.8 1 1 1 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Peptidase_C50 PF03568.12 ETO16478.1 - 7e-05 21.6 3.3 9.2e-05 21.2 2.3 1.1 1 0 0 1 1 1 1 Peptidase family C50 SAM_PNT PF02198.11 ETO16478.1 - 0.011 15.5 0.4 0.017 14.8 0.3 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain CRA PF06589.6 ETO16478.1 - 0.26 10.6 3.8 0.074 12.3 0.3 1.8 3 0 0 3 3 3 0 Circumsporozoite-related antigen (CRA) Cnd1_N PF12922.2 ETO16478.1 - 1.2 8.7 5.5 4.3 6.9 0.9 2.3 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term DUF2774 PF11242.3 ETO16479.1 - 0.031 14.2 0.0 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) BLOC1_2 PF10046.4 ETO16479.1 - 0.89 9.7 38.5 0.47 10.6 2.5 5.2 4 2 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF869 PF05911.6 ETO16479.1 - 1.2 7.2 52.8 0.69 8.0 9.1 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF869) Reo_sigmaC PF04582.7 ETO16479.1 - 1.2 8.2 27.5 0.13 11.4 1.5 4.2 2 2 2 4 4 4 0 Reovirus sigma C capsid protein DUF2543 PF10820.3 ETO16480.1 - 5.4 7.0 7.2 4 7.5 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2543) Sec1 PF00995.18 ETO16481.1 - 4.2e-64 217.1 3.7 6.5e-64 216.5 2.5 1.2 1 0 0 1 1 1 1 Sec1 family UvrD-helicase PF00580.16 ETO16481.1 - 0.059 12.6 0.7 0.082 12.1 0.5 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Sec1 PF00995.18 ETO16482.1 - 3.5e-17 62.2 0.1 4e-17 62.0 0.1 1.0 1 0 0 1 1 1 1 Sec1 family Med21 PF11221.3 ETO16482.1 - 0.12 12.3 0.0 0.58 10.1 0.0 1.8 2 0 0 2 2 2 0 Subunit 21 of Mediator complex MIP-T3 PF10243.4 ETO16484.1 - 3.1e-07 29.2 26.9 5.8e-07 28.3 18.7 1.4 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 zf-C3HC4 PF00097.20 ETO16484.1 - 8.9e-05 22.0 8.4 8.9e-05 22.0 5.8 5.6 6 1 0 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO16484.1 - 0.0014 18.6 11.6 0.0014 18.6 8.0 5.4 6 0 0 6 6 6 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 ETO16484.1 - 0.0014 18.4 0.4 0.0014 18.4 0.3 6.2 4 2 1 5 5 5 2 FYVE zinc finger IBR PF01485.16 ETO16484.1 - 0.0069 16.2 4.8 0.0069 16.2 3.3 6.6 4 2 1 5 5 5 1 IBR domain Mucin PF01456.12 ETO16484.1 - 0.16 11.7 30.3 0.55 10.0 21.0 1.9 1 0 0 1 1 1 0 Mucin-like glycoprotein Borrelia_P83 PF05262.6 ETO16484.1 - 5.5 5.1 30.3 9.2 4.4 21.0 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein CENP-B_dimeris PF09026.5 ETO16485.1 - 0.037 14.2 1.3 0.037 14.2 0.9 1.8 2 1 0 2 2 2 0 Centromere protein B dimerisation domain Voldacs PF03517.8 ETO16485.1 - 0.63 9.8 3.9 0.92 9.3 2.7 1.4 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling SAM_1 PF00536.25 ETO16486.1 - 9.1e-15 54.5 2.0 1.1e-07 31.9 0.2 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO16486.1 - 2.4e-14 52.8 0.8 1.2e-09 37.9 0.1 2.6 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) UPF0242 PF06785.6 ETO16486.1 - 0.0042 15.8 5.1 0.0079 14.9 3.5 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) IncA PF04156.9 ETO16486.1 - 0.012 15.2 2.2 0.012 15.2 1.5 2.9 3 0 0 3 3 3 0 IncA protein FHIPEP PF00771.15 ETO16486.1 - 0.035 12.4 0.1 0.063 11.5 0.1 1.3 1 0 0 1 1 1 0 FHIPEP family SAM_PNT PF02198.11 ETO16486.1 - 0.095 12.4 0.1 0.095 12.4 0.0 2.6 3 0 0 3 3 3 0 Sterile alpha motif (SAM)/Pointed domain Takusan PF04822.8 ETO16486.1 - 0.11 12.2 10.4 0.019 14.6 3.8 2.2 2 0 0 2 2 2 0 Takusan DUF972 PF06156.8 ETO16486.1 - 0.26 11.6 16.5 0.12 12.7 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF972) DUF1043 PF06295.7 ETO16487.1 - 0.041 13.5 1.3 0.68 9.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) Tir_receptor_C PF07489.6 ETO16487.1 - 0.13 11.9 4.4 0.24 11.1 3.1 1.4 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus DUF2014 PF09427.5 ETO16488.1 - 0.019 14.0 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2014) zf-UBR PF02207.15 ETO16489.1 - 6.9e-15 54.5 4.4 1.5e-14 53.4 3.1 1.6 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) zf-B_box PF00643.19 ETO16489.1 - 0.069 13.0 4.5 0.26 11.2 3.1 2.1 1 1 0 1 1 1 0 B-box zinc finger Sybindin PF04099.7 ETO16490.1 - 2.3e-35 121.4 0.0 2.7e-35 121.1 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 ETO16490.1 - 1.8e-08 34.2 0.0 2.4e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region MMS1_N PF10433.4 ETO16491.1 - 5.2e-40 137.0 4.8 1.3e-39 135.7 3.3 1.6 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 ETO16491.1 - 1.9e-35 122.5 0.3 5.8e-35 120.9 0.2 1.9 1 0 0 1 1 1 1 CPSF A subunit region PRF PF06875.6 ETO16491.1 - 0.0029 16.8 0.0 0.0053 15.9 0.0 1.3 1 0 0 1 1 1 1 Plethodontid receptivity factor PRF WD40 PF00400.27 ETO16492.1 - 1.2e-26 91.5 0.3 6.7e-12 44.8 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO16492.1 - 0.00048 18.3 0.2 0.066 11.3 0.0 2.7 1 1 2 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO16492.1 - 0.039 13.4 0.0 0.3 10.5 0.0 1.9 1 1 1 2 2 2 0 PQQ-like domain DUF3601 PF12208.3 ETO16492.1 - 0.049 13.5 0.2 1.6 8.6 0.0 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF3601) Nbas_N PF15492.1 ETO16492.1 - 0.082 11.9 0.2 0.47 9.5 0.0 2.0 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Vhr1 PF04001.8 ETO16493.1 - 0.01 15.7 1.8 0.017 15.0 1.3 1.4 1 0 0 1 1 1 0 Transcription factor Vhr1 DUF1673 PF07895.6 ETO16494.1 - 6.8 6.1 8.2 0.31 10.5 0.7 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1673) WD40 PF00400.27 ETO16495.1 - 2.2e-05 24.1 0.1 3.6e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 WD domain, G-beta repeat EntA_Immun PF08951.5 ETO16495.1 - 0.0054 16.8 2.2 0.01 15.9 1.5 1.5 1 0 0 1 1 1 1 Enterocin A Immunity DUF3484 PF11983.3 ETO16495.1 - 0.14 13.0 0.7 0.31 11.8 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3484) ShK PF01549.19 ETO16496.1 - 2.9e-09 37.1 23.1 4.6e-08 33.2 5.4 2.8 3 0 0 3 3 2 2 ShK domain-like FimP PF09766.4 ETO16496.1 - 0.026 13.6 7.2 0.035 13.1 5.0 1.1 1 0 0 1 1 1 0 Fms-interacting protein ETRAMP PF09716.5 ETO16496.1 - 0.052 13.4 0.0 0.11 12.4 0.0 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) YqfQ PF14181.1 ETO16496.1 - 0.31 11.0 11.0 0.47 10.4 7.6 1.3 1 0 0 1 1 1 0 YqfQ-like protein FdhD-NarQ PF02634.10 ETO16496.1 - 0.7 9.3 6.1 0.95 8.8 4.2 1.2 1 0 0 1 1 1 0 FdhD/NarQ family Peptidase_S49_N PF08496.5 ETO16496.1 - 0.97 9.2 9.2 1.7 8.4 6.4 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FLO_LFY PF01698.11 ETO16496.1 - 1.1 7.9 9.4 1.5 7.5 6.5 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Paramyxo_ncap PF00973.14 ETO16496.1 - 2.2 6.8 4.6 2.7 6.5 3.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein RNase_H2-Ydr279 PF09468.5 ETO16496.1 - 2.4 7.2 10.5 3 6.9 7.3 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Gag_spuma PF03276.9 ETO16496.1 - 2.9 6.1 6.5 3.4 5.8 4.5 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DUF4175 PF13779.1 ETO16496.1 - 4.8 4.7 9.0 5.8 4.4 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) NARP1 PF12569.3 ETO16496.1 - 5 5.7 11.3 7.1 5.2 7.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3464 PF11947.3 ETO16496.1 - 5.2 6.5 7.9 8 5.9 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF2058 PF09831.4 ETO16497.1 - 0.46 10.3 15.5 0.61 9.9 10.7 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) ECIST_Cterm PF14784.1 ETO16497.1 - 0.86 9.5 4.8 0.86 9.5 2.2 1.7 1 1 1 2 2 2 0 C-terminal domain of the ECSIT protein Nucleoside_tran PF01733.13 ETO16497.1 - 0.92 8.6 2.7 0.95 8.5 1.9 1.1 1 0 0 1 1 1 0 Nucleoside transporter UPF0542 PF15086.1 ETO16497.1 - 7.2 6.4 10.5 0.35 10.6 2.8 2.1 2 1 0 2 2 2 0 Uncharacterised protein family UPF0542 PTEN_C2 PF10409.4 ETO16498.1 - 1.6e-12 47.3 0.1 2.2e-12 46.8 0.1 1.2 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DEP PF00610.16 ETO16498.1 - 1.8e-09 37.2 0.0 3.8e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF3973 PF13119.1 ETO16498.1 - 0.28 11.1 1.6 0.36 10.8 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3973) IBR PF01485.16 ETO16499.1 - 1.8e-05 24.5 13.3 1.8e-05 24.5 9.2 3.7 4 0 0 4 4 4 2 IBR domain ubiquitin PF00240.18 ETO16499.1 - 0.0009 18.6 0.1 0.0022 17.3 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 ETO16499.1 - 0.017 14.8 0.0 0.045 13.4 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_60s PF00428.14 ETO16499.1 - 0.044 14.1 13.1 1.3 9.5 3.4 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein RcsC PF09456.5 ETO16500.1 - 0.079 12.6 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 RcsC Alpha-Beta-Loop (ABL) Pkinase PF00069.20 ETO16501.1 - 0.00012 21.3 0.0 0.00016 20.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_6 PF13516.1 ETO16504.1 - 2.7e-08 33.0 27.7 0.0019 18.0 0.4 6.9 6 1 1 7 7 7 4 Leucine Rich repeat LRR_1 PF00560.28 ETO16504.1 - 0.00053 19.6 21.9 0.62 10.3 0.1 7.2 7 1 0 7 7 7 3 Leucine Rich Repeat LRR_4 PF12799.2 ETO16504.1 - 0.028 14.0 24.2 0.25 11.0 0.2 5.7 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO16504.1 - 0.2 11.4 19.4 0.84 9.4 0.1 5.7 6 1 0 6 6 6 0 Leucine rich repeat LRR_7 PF13504.1 ETO16504.1 - 1.2 9.6 10.0 26 5.6 0.0 5.0 4 0 0 4 4 4 0 Leucine rich repeat Ribosomal_S7 PF00177.16 ETO16505.1 - 2.8e-10 39.9 0.0 4.3e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e AAA PF00004.24 ETO16506.1 - 2.8e-29 101.9 0.0 7.3e-29 100.6 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETO16506.1 - 2.5e-05 24.4 0.0 8.5e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETO16506.1 - 0.0004 20.4 0.0 0.0036 17.3 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 ETO16506.1 - 0.0006 19.5 0.0 0.0085 15.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 ETO16506.1 - 0.0019 18.1 0.0 0.0082 16.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 ETO16506.1 - 0.002 17.8 0.0 0.0061 16.2 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 ETO16506.1 - 0.0032 18.2 0.0 0.016 16.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 ETO16506.1 - 0.0077 15.8 1.6 0.0089 15.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 ETO16506.1 - 0.015 15.1 0.0 0.044 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 ETO16506.1 - 0.019 14.1 0.0 0.047 12.8 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 ETO16506.1 - 0.025 14.2 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 ETO16506.1 - 0.039 13.6 5.3 2.9 7.5 3.7 3.4 1 1 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.12 ETO16506.1 - 0.065 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 ETO16506.1 - 0.072 12.4 0.5 0.37 10.1 0.0 2.2 2 1 0 2 2 1 0 AAA domain Zeta_toxin PF06414.7 ETO16506.1 - 0.076 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 ETO16506.1 - 0.11 12.7 0.0 0.11 12.7 0.0 2.2 2 2 0 2 2 2 0 AAA domain TIP49 PF06068.8 ETO16506.1 - 0.14 10.8 0.0 0.27 9.9 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus Pheromone PF08015.6 ETO16506.1 - 0.19 12.5 5.8 0.62 10.9 4.0 1.8 1 0 0 1 1 1 0 Fungal mating-type pheromone Fringe PF02434.11 ETO16507.1 - 1e-06 28.1 0.8 4.7e-06 25.9 0.6 2.1 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 ETO16507.1 - 0.0039 16.8 0.5 0.022 14.3 0.3 2.4 2 1 0 2 2 2 1 Galactosyltransferase AAA_4 PF04326.9 ETO16507.1 - 0.015 15.4 0.3 0.024 14.7 0.2 1.3 1 0 0 1 1 1 0 Divergent AAA domain FAM131 PF15010.1 ETO16508.1 - 2.5 7.7 5.1 22 4.6 0.1 2.1 2 0 0 2 2 2 0 Putative cell signalling WD40 PF00400.27 ETO16509.1 - 8.4e-72 234.7 29.2 1e-11 44.2 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO16509.1 - 1.1e-10 41.6 1.1 1.6e-06 27.9 0.0 3.3 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO16509.1 - 6.6e-06 24.5 10.1 0.94 7.5 0.2 6.3 1 1 5 6 6 6 3 Nucleoporin Nup120/160 Resistin PF06954.6 ETO16509.1 - 9.5e-05 22.6 6.6 14 6.0 0.0 5.2 1 1 2 5 5 5 2 Resistin Nucleoporin_N PF08801.6 ETO16509.1 - 0.00012 20.9 8.4 0.75 8.4 0.4 4.4 2 2 2 4 4 4 3 Nup133 N terminal like DUF1652 PF07865.6 ETO16509.1 - 0.022 14.3 0.2 42 3.8 0.0 4.4 4 2 2 6 6 6 0 Protein of unknown function (DUF1652) Proteasome_A_N PF10584.4 ETO16509.1 - 0.5 9.7 1.7 59 3.1 0.0 3.7 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature FACT-Spt16_Nlob PF14826.1 ETO16511.1 - 0.033 13.7 0.0 0.069 12.6 0.0 1.5 1 0 0 1 1 1 0 FACT complex subunit SPT16 N-terminal lobe domain Neur_chan_memb PF02932.11 ETO16512.1 - 0.026 14.4 3.2 0.033 14.0 2.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TrbC_Ftype PF09673.5 ETO16512.1 - 0.11 12.0 1.8 0.19 11.3 0.9 1.9 1 1 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein Pkinase PF00069.20 ETO16514.1 - 1.3e-33 116.3 0.9 1.7e-33 115.8 0.6 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO16514.1 - 8e-08 31.6 1.5 0.0022 17.0 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 ETO16514.1 - 0.0089 14.8 0.1 0.013 14.3 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase IPK PF03770.11 ETO16514.1 - 0.021 14.4 2.2 0.044 13.4 1.5 1.5 1 1 0 1 1 1 0 Inositol polyphosphate kinase DUF2250 PF10007.4 ETO16515.1 - 0.21 11.5 0.0 0.21 11.5 0.0 2.1 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) NT-C2 PF10358.4 ETO16516.1 - 0.0031 17.0 0.8 0.0059 16.1 0.6 1.6 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Hydrolase_3 PF08282.7 ETO16516.1 - 0.14 11.6 0.6 0.18 11.3 0.4 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase SPRY PF00622.23 ETO16517.1 - 8.1e-07 29.1 0.1 2.1e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 SPRY domain DEAD PF00270.24 ETO16518.1 - 0.0001 21.8 0.0 0.00014 21.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_29 PF13555.1 ETO16518.1 - 0.025 14.0 0.0 0.051 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 ETO16518.1 - 0.072 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain EssA PF10661.4 ETO16519.1 - 0.003 17.2 2.9 0.003 17.2 2.0 1.7 2 0 0 2 2 2 1 WXG100 protein secretion system (Wss), protein EssA Metallothio_Pro PF02069.11 ETO16519.1 - 0.052 13.3 2.2 4.3 7.2 0.5 2.6 2 0 0 2 2 2 0 Prokaryotic metallothionein Ribosomal_S25 PF03297.10 ETO16520.1 - 1e-17 64.1 17.7 2e-17 63.1 3.0 5.7 1 1 3 4 4 4 2 S25 ribosomal protein HTH_DeoR PF08220.7 ETO16520.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain DUF3595 PF12166.3 ETO16521.1 - 0.56 8.9 4.5 0.9 8.2 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) SprA-related PF12118.3 ETO16521.1 - 0.69 9.1 13.2 0.99 8.6 9.1 1.1 1 0 0 1 1 1 0 SprA-related family Secretin_N_2 PF07655.8 ETO16521.1 - 1.4 9.3 14.2 3.4 8.1 9.9 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain Eapp_C PF10238.4 ETO16521.1 - 2.6 7.9 17.4 3.1 7.7 8.3 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein Daxx PF03344.10 ETO16521.1 - 6 5.2 17.4 8.7 4.6 12.1 1.2 1 0 0 1 1 1 0 Daxx Family Prothymosin PF03247.9 ETO16521.1 - 6.1 7.0 38.1 1.4 9.1 17.5 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family Neur_chan_memb PF02932.11 ETO16521.1 - 8.1 6.2 8.4 13 5.5 5.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NPR3 PF03666.8 ETO16521.1 - 8.8 4.7 9.8 19 3.6 6.8 1.5 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TMF_TATA_bd PF12325.3 ETO16522.1 - 0.00038 20.1 0.6 0.00038 20.1 0.4 2.5 3 0 0 3 3 3 1 TATA element modulatory factor 1 TATA binding DivIC PF04977.10 ETO16522.1 - 0.0017 17.8 3.3 0.0017 17.8 2.3 3.0 3 2 0 3 3 2 1 Septum formation initiator PGBA_C PF15437.1 ETO16522.1 - 0.0019 18.3 14.3 0.0019 18.3 9.9 1.9 2 0 0 2 2 1 1 Plasminogen-binding protein pgbA C-terminal ATG16 PF08614.6 ETO16522.1 - 0.0033 17.2 4.2 0.0033 17.2 2.9 2.7 2 1 1 3 3 1 1 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.3 ETO16522.1 - 0.0042 16.8 3.4 0.0042 16.8 2.4 2.7 2 0 0 2 2 1 1 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.16 ETO16522.1 - 0.0049 16.7 2.2 0.0049 16.7 1.5 2.2 2 1 1 3 3 3 1 bZIP transcription factor Reo_sigmaC PF04582.7 ETO16522.1 - 0.013 14.7 5.5 0.022 13.9 3.8 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein BRE1 PF08647.6 ETO16522.1 - 0.018 14.9 1.9 0.018 14.9 1.3 2.8 2 1 0 2 2 1 0 BRE1 E3 ubiquitin ligase Rootletin PF15035.1 ETO16522.1 - 0.019 14.9 3.4 0.019 14.9 2.3 3.1 2 1 1 3 3 2 0 Ciliary rootlet component, centrosome cohesion ADIP PF11559.3 ETO16522.1 - 0.024 14.5 4.2 0.024 14.5 2.9 2.8 2 1 0 2 2 1 0 Afadin- and alpha -actinin-Binding DUF904 PF06005.7 ETO16522.1 - 0.026 14.8 0.0 0.026 14.8 0.0 2.7 2 1 0 2 2 1 0 Protein of unknown function (DUF904) DUF972 PF06156.8 ETO16522.1 - 0.06 13.7 0.3 0.06 13.7 0.2 2.7 2 1 1 3 3 2 0 Protein of unknown function (DUF972) KIAA1328 PF15369.1 ETO16522.1 - 0.2 11.4 24.3 0.26 11.0 16.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 Folate_carrier PF01770.13 ETO16522.1 - 0.91 7.9 3.1 1.2 7.5 2.1 1.2 1 0 0 1 1 1 0 Reduced folate carrier CobU PF02283.11 ETO16522.1 - 3.8 6.8 6.7 1 8.7 0.3 2.1 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase SR-25 PF10500.4 ETO16522.1 - 6.3 6.2 29.8 14 5.0 20.6 1.8 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein WD40 PF00400.27 ETO16523.1 - 1.8e-40 135.4 17.6 8.1e-10 38.2 0.2 5.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO16523.1 - 1.2e-07 30.2 1.2 0.11 10.5 0.0 4.3 3 1 0 4 4 4 4 Nucleoporin Nup120/160 Histone PF00125.19 ETO16526.1 - 4.7e-21 74.6 0.2 1.2e-20 73.3 0.1 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF837 PF05769.6 ETO16528.1 - 0.001 18.6 4.1 0.0019 17.7 2.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF837) PUB PF09409.5 ETO16528.1 - 0.021 14.5 1.3 0.021 14.5 0.9 3.2 2 1 1 3 3 3 0 PUB domain Spore_III_AB PF09548.5 ETO16528.1 - 0.029 14.1 1.2 0.11 12.2 0.9 1.9 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DUF3753 PF12575.3 ETO16530.1 - 0.6 9.9 5.1 0.83 9.4 3.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3753) Oxidored_q3 PF00499.15 ETO16530.1 - 0.81 9.4 4.6 0.82 9.4 3.2 1.1 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Act-Frag_cataly PF09192.5 ETO16530.1 - 2.2 7.2 12.9 2.5 6.9 9.0 1.1 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic PepX_C PF08530.5 ETO16531.1 - 8.5e-29 100.9 0.0 9.1e-29 100.8 0.0 1.0 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 7TM-7TMR_HD PF07698.6 ETO16531.1 - 0.16 11.4 1.2 0.26 10.7 0.9 1.3 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase Peptidase_S10 PF00450.17 ETO16533.1 - 2.8e-20 72.8 2.9 6.8e-11 41.9 0.1 2.4 1 1 1 2 2 2 2 Serine carboxypeptidase Tetraspannin PF00335.15 ETO16533.1 - 0.055 12.7 1.8 0.14 11.4 0.8 2.0 1 1 0 1 1 1 0 Tetraspanin family Peptidase_S10 PF00450.17 ETO16534.1 - 1.9e-59 201.9 7.0 3.3e-47 161.5 2.5 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase G-alpha PF00503.15 ETO16535.1 - 1.2e-06 27.5 6.4 2.3e-06 26.5 4.5 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Baculo_11_kDa PF06143.6 ETO16536.1 - 0.061 12.6 0.2 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family Ribosomal_L9_C PF03948.9 ETO16537.1 - 0.0048 16.9 0.1 0.0083 16.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain OEP PF02321.13 ETO16537.1 - 0.092 12.3 3.0 0.062 12.8 0.7 1.7 2 0 0 2 2 2 0 Outer membrane efflux protein PH_10 PF15411.1 ETO16537.1 - 0.26 11.4 2.4 0.46 10.6 1.7 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain TPR_12 PF13424.1 ETO16540.1 - 9.6e-82 268.9 21.9 5e-20 71.2 0.7 6.2 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETO16540.1 - 7.8e-41 136.0 40.9 1e-07 31.2 0.3 8.7 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.1 ETO16540.1 - 3.3e-40 134.8 0.0 2.1e-08 33.8 0.0 8.4 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_11 PF13414.1 ETO16540.1 - 2.5e-38 129.5 34.9 5.3e-12 45.2 0.1 6.9 5 2 2 7 7 7 6 TPR repeat TPR_7 PF13176.1 ETO16540.1 - 3.7e-33 110.6 13.4 2e-05 24.0 0.1 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.12 ETO16540.1 - 4.9e-28 94.7 37.8 1.6e-05 24.4 0.8 9.8 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.1 ETO16540.1 - 6.3e-27 91.2 50.9 2e-06 27.1 0.3 10.2 10 0 0 10 10 9 8 Tetratricopeptide repeat TPR_16 PF13432.1 ETO16540.1 - 3.1e-18 65.9 5.1 2e-05 25.1 0.0 7.3 4 3 5 9 9 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 ETO16540.1 - 1.2e-13 50.3 1.3 0.36 11.5 0.0 8.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO16540.1 - 4.7e-11 41.9 13.4 0.012 15.7 0.1 9.0 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO16540.1 - 3.8e-09 36.4 13.4 1.2 9.7 0.0 8.2 9 0 0 9 9 8 3 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO16540.1 - 8.2e-08 31.3 6.4 0.016 14.4 0.1 5.9 8 0 0 8 8 8 2 SHNi-TPR Apc3 PF12895.2 ETO16540.1 - 6.6e-07 29.3 22.0 0.00021 21.3 1.3 5.6 2 1 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO16540.1 - 1.8e-05 25.0 7.0 0.12 12.7 0.1 5.0 4 1 0 5 5 4 2 Tetratricopeptide repeat MIT PF04212.13 ETO16540.1 - 0.0004 20.2 14.7 1.4 8.8 0.1 7.4 8 0 0 8 8 7 1 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 ETO16540.1 - 5.9 6.7 37.2 0.063 13.1 1.2 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF892 PF05974.7 ETO16541.1 - 0.025 14.3 0.5 0.026 14.3 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF892) PCI PF01399.22 ETO16541.1 - 0.095 13.0 0.4 0.12 12.6 0.3 1.3 1 0 0 1 1 1 0 PCI domain CUE PF02845.11 ETO16541.1 - 0.11 12.0 0.3 0.2 11.1 0.1 1.7 1 1 0 1 1 1 0 CUE domain Peptidase_C14 PF00656.17 ETO16542.1 - 0.00021 21.0 4.2 0.00083 19.1 0.1 2.3 1 1 1 2 2 2 2 Caspase domain SPAN-X PF07458.7 ETO16543.1 - 0.0099 16.0 0.7 0.0099 16.0 0.5 2.1 2 0 0 2 2 2 1 Sperm protein associated with nucleus, mapped to X chromosome DUF1178 PF06676.6 ETO16543.1 - 0.037 14.2 1.0 0.037 14.2 0.7 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1178) Velvet PF11754.3 ETO16543.1 - 0.089 12.3 1.4 0.099 12.2 0.5 1.3 1 1 0 1 1 1 0 Velvet factor WD40 PF00400.27 ETO16544.1 - 3.5e-07 29.8 0.9 0.0034 17.2 0.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat Exo_endo_phos_2 PF14529.1 ETO16545.1 - 0.011 15.3 0.2 0.027 14.0 0.1 1.7 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase HGWP PF03578.10 ETO16545.1 - 0.075 12.3 0.5 0.16 11.2 0.4 1.5 1 0 0 1 1 1 0 HGWP repeat Kelch_1 PF01344.20 ETO16545.1 - 0.17 11.4 0.7 0.31 10.6 0.5 1.5 1 0 0 1 1 1 0 Kelch motif HTH_19 PF12844.2 ETO16546.1 - 0.0047 16.9 0.0 0.009 16.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Kelch_2 PF07646.10 ETO16547.1 - 0.0019 17.8 0.2 0.12 12.2 0.0 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETO16547.1 - 0.057 13.6 0.1 0.65 10.2 0.0 2.2 2 0 0 2 2 2 0 Kelch motif Kelch_1 PF01344.20 ETO16547.1 - 0.18 11.3 0.9 2.1 7.9 0.0 2.6 3 1 0 3 3 3 0 Kelch motif 3H PF02829.9 ETO16548.1 - 0.28 11.2 6.9 11 6.1 0.6 3.7 2 1 2 4 4 4 0 3H domain Sp38 PF07354.7 ETO16548.1 - 1.2 7.7 5.6 1.2 7.7 2.9 1.6 1 1 1 2 2 2 0 Zona-pellucida-binding protein (Sp38) CAP_GLY PF01302.20 ETO16549.1 - 5.4e-09 35.6 0.2 1e-08 34.7 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain CLASP_N PF12348.3 ETO16549.1 - 0.004 16.5 0.5 0.67 9.2 0.2 2.5 2 1 0 2 2 2 2 CLASP N terminal Peptidase_M24 PF00557.19 ETO16550.1 - 2.6e-36 125.1 0.6 9.5e-36 123.3 0.4 1.8 1 1 0 1 1 1 1 Metallopeptidase family M24 tRNA-synt_2b PF00587.20 ETO16553.1 - 2.7e-40 137.7 0.1 9.5e-40 135.9 0.0 2.0 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 ETO16553.1 - 1.2e-21 76.4 0.2 4.5e-21 74.5 0.1 2.0 2 0 0 2 2 2 1 Anticodon binding domain TGS PF02824.16 ETO16553.1 - 5.9e-15 54.8 0.0 1.2e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.9 ETO16553.1 - 1.4e-11 44.0 0.0 3.3e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Pkinase PF00069.20 ETO16555.1 - 7.6e-42 143.2 2.3 7.6e-42 143.2 1.6 2.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO16555.1 - 8.3e-28 97.1 0.3 2.9e-25 88.8 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 ETO16555.1 - 6.3e-07 28.6 0.0 1.4e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like SR-25 PF10500.4 ETO16555.1 - 0.016 14.6 26.9 0.099 12.1 11.0 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 ETO16555.1 - 4.9 6.4 38.8 3.4 6.9 4.1 2.4 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SOBP PF15279.1 ETO16555.1 - 9.5 6.5 17.9 15 5.8 0.6 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein WD40 PF00400.27 ETO16556.1 - 3.3e-46 153.5 9.7 3.4e-12 45.7 0.5 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO16556.1 - 6.4e-08 31.1 0.4 0.86 7.6 0.0 4.0 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO16556.1 - 0.00095 19.2 3.9 2.3 8.5 0.1 3.9 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.1 ETO16557.1 - 1.2e-06 28.2 1.6 9.4e-05 22.0 0.1 3.3 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO16557.1 - 0.0003 20.2 4.7 0.00068 19.1 1.0 3.3 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 ETO16557.1 - 0.00051 19.6 2.3 0.0091 15.7 0.3 3.7 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 ETO16557.1 - 0.00067 19.5 0.9 2.4 8.2 0.2 4.4 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 ETO16557.1 - 0.016 15.3 0.2 0.14 12.3 0.0 2.7 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO16557.1 - 0.27 11.4 6.8 3.8 7.8 0.4 4.3 4 2 1 5 5 5 0 Kelch motif P-mevalo_kinase PF04275.9 ETO16557.1 - 0.35 10.5 6.2 0.15 11.7 2.1 2.0 2 0 0 2 2 2 0 Phosphomevalonate kinase TPR_12 PF13424.1 ETO16559.1 - 7.5e-29 99.5 0.9 3.3e-13 49.3 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO16559.1 - 3.3e-22 77.9 5.2 8.8e-13 47.7 0.7 2.7 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETO16559.1 - 3.7e-18 64.2 13.8 6.8e-10 38.1 1.6 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO16559.1 - 4.8e-18 63.5 12.1 6.3e-06 25.7 0.9 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO16559.1 - 5.1e-18 63.3 4.3 9.2e-06 25.0 0.4 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO16559.1 - 4.8e-16 57.2 11.7 4.5e-07 29.1 0.9 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO16559.1 - 1e-14 53.8 0.0 2.1e-06 27.4 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO16559.1 - 4.6e-10 39.8 0.0 3.6e-05 24.2 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO16559.1 - 1.6e-08 34.1 0.9 0.0013 18.7 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO16559.1 - 2.9e-08 33.6 5.5 9.9e-05 22.5 0.6 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO16559.1 - 2e-07 31.0 2.8 4.2e-07 30.0 1.1 2.3 2 0 0 2 2 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 ETO16559.1 - 5.4e-07 29.6 0.1 0.094 13.3 0.0 4.2 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO16559.1 - 6.4e-06 26.4 0.4 0.0017 18.6 0.2 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO16559.1 - 2.9e-05 23.2 0.6 0.41 9.9 0.0 3.3 3 0 0 3 3 3 2 SHNi-TPR Fis1_TPR_C PF14853.1 ETO16559.1 - 0.003 17.3 3.8 0.22 11.4 0.2 3.0 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.7 ETO16559.1 - 0.0036 17.0 5.9 1.1 9.0 0.7 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat MIT PF04212.13 ETO16559.1 - 0.0046 16.8 4.9 0.032 14.1 0.4 4.0 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain Sel1 PF08238.7 ETO16559.1 - 0.19 12.4 6.1 0.98 10.1 0.3 3.6 4 0 0 4 4 3 0 Sel1 repeat PPR PF01535.15 ETO16559.1 - 0.28 11.2 3.5 22 5.2 0.0 4.1 4 0 0 4 4 4 0 PPR repeat AFT PF08731.6 ETO16560.1 - 0.052 13.7 1.5 0.069 13.3 1.0 1.1 1 0 0 1 1 1 0 Transcription factor AFT DUF3816 PF12822.2 ETO16561.1 - 0.0012 18.7 2.6 0.0012 18.7 1.8 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3816) PRA1 PF03208.14 ETO16561.1 - 0.023 14.0 10.2 0.02 14.2 2.6 2.4 2 1 0 2 2 2 0 PRA1 family protein PLAC8 PF04749.12 ETO16561.1 - 0.048 14.2 8.4 0.26 11.8 0.6 2.3 2 0 0 2 2 2 0 PLAC8 family Secretin_N_2 PF07655.8 ETO16561.1 - 0.13 12.6 6.1 0.2 12.0 4.2 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain Ninjurin PF04923.7 ETO16561.1 - 0.59 9.8 3.2 23 4.7 0.7 3.1 2 1 1 3 3 3 0 Ninjurin RRM_1 PF00076.17 ETO16563.1 - 2e-16 59.3 1.0 3.2e-14 52.3 0.2 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO16563.1 - 4e-11 42.7 0.3 1.2e-09 37.9 0.1 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO16563.1 - 2.5e-08 33.6 0.2 4.1e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 ETO16563.1 - 0.00013 21.6 0.1 0.00019 21.0 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif ABC_tran PF00005.22 ETO16564.1 - 4.8e-05 23.6 0.1 5.8e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_5 PF07728.9 ETO16564.1 - 8e-05 22.3 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF258 PF03193.11 ETO16564.1 - 0.00066 18.8 0.0 0.00077 18.6 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA PF00004.24 ETO16564.1 - 0.00069 19.8 0.2 0.00098 19.3 0.1 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 ETO16564.1 - 0.0013 18.4 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase Miro PF08477.8 ETO16564.1 - 0.002 18.6 0.1 0.0031 17.9 0.1 1.4 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 ETO16564.1 - 0.0058 16.7 0.0 0.0076 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 ETO16564.1 - 0.0063 16.8 0.0 0.0067 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 ETO16564.1 - 0.0072 15.4 0.3 0.0073 15.3 0.2 1.1 1 0 0 1 1 1 1 AAA ATPase domain Transp_Tc5_C PF04236.10 ETO16564.1 - 0.0092 16.1 0.2 0.021 15.0 0.1 1.6 1 0 0 1 1 1 1 Tc5 transposase C-terminal domain DUF815 PF05673.8 ETO16564.1 - 0.019 13.8 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PduV-EutP PF10662.4 ETO16564.1 - 0.021 14.3 0.6 0.032 13.7 0.2 1.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 ETO16564.1 - 0.022 14.7 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activ_2 PF14532.1 ETO16564.1 - 0.022 14.7 0.0 0.026 14.5 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_21 PF13304.1 ETO16564.1 - 0.029 14.3 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 ETO16564.1 - 0.038 13.6 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain cobW PF02492.14 ETO16564.1 - 0.041 13.3 0.1 0.055 12.9 0.1 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Sigma54_activat PF00158.21 ETO16564.1 - 0.055 12.9 0.0 0.08 12.4 0.0 1.3 1 1 0 1 1 1 0 Sigma-54 interaction domain Viral_helicase1 PF01443.13 ETO16564.1 - 0.072 12.5 0.2 0.082 12.4 0.2 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 ETO16564.1 - 0.074 12.4 0.0 0.074 12.4 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 ETO16564.1 - 0.082 12.3 0.0 0.089 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Y_phosphatase PF00102.22 ETO16564.1 - 0.093 12.0 0.1 0.1 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase AAA_19 PF13245.1 ETO16564.1 - 0.098 12.4 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Part of AAA domain UPF0079 PF02367.12 ETO16564.1 - 0.11 12.0 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 ETO16564.1 - 0.12 12.5 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase FpoO PF10621.4 ETO16564.1 - 0.14 12.2 1.6 0.57 10.2 0.7 1.9 1 1 0 2 2 2 0 F420H2 dehydrogenase subunit FpoO zf-CCCH PF00642.19 ETO16565.1 - 6.5e-09 35.2 0.9 6.5e-09 35.2 0.6 2.1 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Dynamin_N PF00350.18 ETO16565.1 - 0.19 11.5 3.1 0.33 10.7 2.2 1.4 1 0 0 1 1 1 0 Dynamin family TetR_C_6 PF13977.1 ETO16566.1 - 0.032 14.2 0.0 0.14 12.2 0.0 2.1 1 0 0 1 1 1 0 Bacterial transcriptional repressor zf-C3HC4_2 PF13923.1 ETO16567.1 - 0.0032 17.4 3.6 0.024 14.6 2.5 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Cys_knot PF00007.17 ETO16567.1 - 0.0085 16.1 4.9 0.01 15.8 3.4 1.2 1 0 0 1 1 1 1 Cystine-knot domain Tet_JBP PF12851.2 ETO16567.1 - 0.17 11.1 0.8 0.19 11.0 0.5 1.0 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily 14-3-3 PF00244.15 ETO16568.1 - 7.6e-81 270.6 5.3 1e-80 270.2 3.7 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 ETO16568.1 - 1.4e-07 31.3 0.6 2.5e-07 30.5 0.4 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO16568.1 - 0.0016 18.0 0.5 0.0042 16.7 0.3 1.8 1 1 0 1 1 1 1 TPR repeat TPR_10 PF13374.1 ETO16568.1 - 0.0027 17.5 0.1 0.031 14.1 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO16568.1 - 0.018 14.8 4.8 0.074 12.8 0.7 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1987 PF09345.5 ETO16568.1 - 0.021 14.6 0.4 0.16 11.7 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1987) TPR_6 PF13174.1 ETO16568.1 - 0.2 12.2 0.9 20 5.8 0.0 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETO16568.1 - 0.36 10.5 4.3 0.4 10.3 0.5 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETO16568.1 - 0.45 10.5 7.3 1.5 8.9 2.0 2.9 2 2 0 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.27 ETO16570.1 - 4.3e-13 48.5 7.2 1.6e-05 24.5 0.3 4.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO16572.1 - 0.0017 18.4 3.1 0.045 13.9 0.1 3.4 3 1 1 4 4 4 1 Kelch motif Orthopox_B11R PF07033.6 ETO16573.1 - 3.4 7.2 10.3 7.9 6.0 0.4 2.7 2 1 0 2 2 2 0 Orthopoxvirus B11R protein AAA_23 PF13476.1 ETO16574.1 - 0.028 14.7 5.3 0.036 14.4 3.6 1.1 1 0 0 1 1 1 0 AAA domain ETRAMP PF09716.5 ETO16574.1 - 0.065 13.2 5.6 0.044 13.7 1.1 2.1 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF4285 PF14113.1 ETO16574.1 - 0.11 12.5 2.3 0.18 11.8 1.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4285) DUF1797 PF08796.5 ETO16574.1 - 1.6 8.6 4.5 0.21 11.4 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1797) Kelch_4 PF13418.1 ETO16575.1 - 4.9e-05 23.0 0.6 0.31 10.8 0.1 2.4 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO16575.1 - 7e-05 22.8 1.2 0.19 11.9 0.9 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.20 ETO16575.1 - 8.7e-05 21.9 2.6 0.0054 16.2 1.6 2.7 2 1 0 2 2 2 1 Kelch motif Kelch_2 PF07646.10 ETO16575.1 - 0.0044 16.7 2.4 3.3 7.6 1.2 2.8 2 1 0 2 2 2 2 Kelch motif Kelch_5 PF13854.1 ETO16575.1 - 0.038 13.9 1.1 0.39 10.7 1.2 2.0 2 0 0 2 2 2 0 Kelch motif DcpS_C PF11969.3 ETO16575.1 - 0.053 13.7 0.2 0.093 12.9 0.1 1.3 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding RPEL PF02755.10 ETO16576.1 - 0.00087 18.5 5.5 0.0024 17.1 1.4 2.5 2 1 0 2 2 2 1 RPEL repeat Mhr1 PF12829.2 ETO16576.1 - 0.0051 16.6 0.7 0.009 15.8 0.5 1.4 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination 2OG-Fe_Oxy_2 PF10014.4 ETO16576.1 - 0.0053 16.1 0.5 0.0067 15.8 0.3 1.2 1 0 0 1 1 1 1 2OG-Fe dioxygenase Rep_4 PF05797.6 ETO16576.1 - 0.086 11.5 2.7 0.099 11.3 1.9 1.0 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) CDC45 PF02724.9 ETO16576.1 - 0.37 8.7 10.3 0.4 8.6 7.1 1.1 1 0 0 1 1 1 0 CDC45-like protein PRP1_N PF06424.7 ETO16576.1 - 1.8 8.9 7.8 2.4 8.5 5.4 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal AAA_23 PF13476.1 ETO16576.1 - 1.9 8.7 7.9 2.2 8.5 5.5 1.1 1 0 0 1 1 1 0 AAA domain RPEL PF02755.10 ETO16577.1 - 0.00042 19.5 7.9 0.0037 16.5 0.3 2.7 3 0 0 3 3 3 2 RPEL repeat Surfac_D-trimer PF09006.6 ETO16577.1 - 0.022 14.4 0.3 0.045 13.4 0.2 1.5 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation EF-hand_7 PF13499.1 ETO16578.1 - 6.1e-08 32.6 3.2 0.00064 19.8 0.6 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 ETO16578.1 - 9.5e-06 24.5 11.7 0.00029 19.9 1.0 3.5 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 ETO16578.1 - 6.7e-05 22.4 1.0 6.7e-05 22.4 0.7 2.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO16578.1 - 0.00042 19.9 14.2 0.0074 16.0 0.3 3.5 3 1 0 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.4 ETO16578.1 - 0.0071 16.3 4.0 0.0097 15.9 2.8 1.3 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region DUF3492 PF11997.3 ETO16578.1 - 0.13 11.7 0.1 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) Phage-scaffold PF09306.5 ETO16578.1 - 0.43 9.6 4.5 0.47 9.5 0.1 2.0 1 1 1 2 2 2 0 Bacteriophage, scaffolding protein EF-hand_5 PF13202.1 ETO16578.1 - 8.9 5.8 7.6 33 4.0 1.5 3.3 2 2 0 2 2 2 0 EF hand WD40 PF00400.27 ETO16579.1 - 1.5e-23 81.7 1.1 3.3e-08 33.1 0.0 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat eIF2A PF08662.6 ETO16579.1 - 0.00058 19.6 0.0 0.54 9.9 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 ETO16579.1 - 0.04 13.0 0.1 3.5 6.6 0.0 2.6 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal DNA_pol3_delta2 PF13177.1 ETO16581.1 - 0.026 14.1 2.0 0.026 14.1 1.4 1.7 2 0 0 2 2 2 0 DNA polymerase III, delta subunit AvrE PF11725.3 ETO16581.1 - 1.7 5.5 15.7 1.8 5.4 10.9 1.0 1 0 0 1 1 1 0 Pathogenicity factor Androgen_recep PF02166.11 ETO16582.1 - 0.93 8.2 5.8 1 8.1 4.0 1.2 1 0 0 1 1 1 0 Androgen receptor DUF4653 PF15546.1 ETO16583.1 - 0.02 14.1 11.7 0.022 14.0 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) Neur_chan_memb PF02932.11 ETO16583.1 - 0.23 11.3 4.9 0.29 10.9 3.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TP53IP5 PF15331.1 ETO16583.1 - 2.7 7.8 12.1 3.2 7.5 8.4 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 PAZ PF02170.17 ETO16586.1 - 9.7e-09 34.6 4.5 2.5e-08 33.3 3.1 1.7 1 0 0 1 1 1 1 PAZ domain FliG_C PF01706.11 ETO16586.1 - 0.08 12.9 2.9 7.4 6.6 0.1 3.3 3 0 0 3 3 3 0 FliG C-terminal domain WD40 PF00400.27 ETO16587.1 - 8.6e-10 38.1 0.2 0.00046 19.9 0.0 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat Pentapeptide PF00805.17 ETO16587.1 - 4.2e-08 32.2 0.2 1.3e-07 30.7 0.2 1.8 1 1 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO16587.1 - 2.2e-06 27.4 0.0 5.6e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 ETO16587.1 - 0.00021 21.1 0.1 0.0018 18.1 0.0 2.2 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) PD40 PF07676.7 ETO16587.1 - 0.48 10.1 5.4 3.9 7.2 0.1 3.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat U-box PF04564.10 ETO16589.1 - 1.9e-19 69.3 0.1 1.9e-19 69.3 0.1 1.9 2 0 0 2 2 2 1 U-box domain zf-Nse PF11789.3 ETO16589.1 - 1e-05 24.9 0.0 2.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 ETO16589.1 - 0.00066 19.3 0.0 0.0031 17.2 0.0 2.2 2 0 0 2 2 2 1 RING-type zinc-finger POX PF07526.6 ETO16589.1 - 8.8 6.5 9.0 25 5.0 3.5 2.4 2 0 0 2 2 2 0 Associated with HOX bZIP_1 PF00170.16 ETO16590.1 - 0.02 14.8 2.3 0.03 14.2 0.1 2.5 2 0 0 2 2 2 0 bZIP transcription factor Cytochrom_C_2 PF01322.15 ETO16590.1 - 0.049 14.1 0.4 0.049 14.1 0.3 2.9 3 0 0 3 3 3 0 Cytochrome C' TipAS PF07739.8 ETO16591.1 - 2.1 8.7 5.4 97 3.3 0.0 3.7 4 0 0 4 4 4 0 TipAS antibiotic-recognition domain Kelch_4 PF13418.1 ETO16592.1 - 0.017 14.9 0.6 3.4 7.5 0.0 2.8 1 1 1 2 2 2 0 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO16592.1 - 0.018 15.2 2.0 14 6.0 0.1 4.0 4 0 0 4 4 4 0 Kelch motif WD40 PF00400.27 ETO16593.1 - 2.9e-51 169.6 21.0 2.7e-10 39.7 0.3 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat DUF3312 PF11768.3 ETO16593.1 - 0.028 12.6 0.0 0.087 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) FA_desaturase PF00487.19 ETO16594.1 - 9.4e-27 94.0 21.9 4.6e-26 91.7 15.2 1.8 1 1 0 1 1 1 1 Fatty acid desaturase WD40 PF00400.27 ETO16595.1 - 1.2e-08 34.5 1.6 0.00024 20.8 0.2 3.0 2 2 0 2 2 2 2 WD domain, G-beta repeat Sulf_transp PF04143.9 ETO16596.1 - 1.9e-11 43.8 29.5 4.8e-09 36.1 7.8 4.7 3 2 1 4 4 4 2 Sulphur transport LCCL PF03815.14 ETO16596.1 - 0.061 13.3 0.1 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 LCCL domain DsbD_2 PF13386.1 ETO16597.1 - 3.1e-06 27.0 2.3 3.1e-06 27.0 1.6 1.6 2 0 0 2 2 2 1 Cytochrome C biogenesis protein transmembrane region DUF1454 PF07305.7 ETO16597.1 - 0.033 13.2 0.0 0.06 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) Srg PF02118.16 ETO16597.1 - 0.05 13.0 4.0 0.16 11.3 1.1 2.1 2 0 0 2 2 2 0 Srg family chemoreceptor BRO1 PF03097.13 ETO16598.1 - 1.8e-12 46.7 4.5 1.3e-11 43.9 3.2 1.9 1 1 0 1 1 1 1 BRO1-like domain DUF2313 PF10076.4 ETO16598.1 - 0.052 12.9 0.1 8.5 5.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2313) COG5 PF10392.4 ETO16601.1 - 0.0019 18.1 5.4 0.0023 17.8 3.4 1.4 1 1 0 1 1 1 1 Golgi transport complex subunit 5 DUF1985 PF09331.6 ETO16601.1 - 0.025 14.3 1.2 0.048 13.4 0.4 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1985) DUF1192 PF06698.6 ETO16601.1 - 0.03 14.1 1.7 0.03 14.1 1.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) PH PF00169.24 ETO16602.1 - 1.4e-11 44.4 2.2 1.4e-11 44.4 1.6 2.3 3 0 0 3 3 3 1 PH domain PH_11 PF15413.1 ETO16602.1 - 1.4e-09 38.1 1.4 1.4e-09 38.1 0.9 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.1 ETO16602.1 - 0.00021 21.3 1.9 0.00036 20.5 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain Mcp5_PH PF12814.2 ETO16602.1 - 0.0013 18.6 1.6 0.0013 18.6 1.1 2.4 2 1 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology PH_8 PF15409.1 ETO16602.1 - 0.0017 18.4 1.6 0.025 14.6 1.0 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain PMAIP1 PF15150.1 ETO16602.1 - 0.021 14.5 0.3 0.047 13.4 0.2 1.6 1 0 0 1 1 1 0 Phorbol-12-myristate-13-acetate-induced PH_3 PF14593.1 ETO16602.1 - 0.083 12.7 2.1 0.47 10.3 0.0 2.7 3 0 0 3 3 3 0 PH domain Pex14_N PF04695.8 ETO16602.1 - 4.1 7.4 11.1 0.99 9.4 4.3 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Aha1_N PF09229.6 ETO16603.1 - 1.8e-10 40.7 13.0 1.2e-09 38.1 1.8 3.0 3 0 0 3 3 3 2 Activator of Hsp90 ATPase, N-terminal DUF2207 PF09972.4 ETO16603.1 - 6.3 5.2 10.8 0.021 13.4 0.6 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) SAPS PF04499.10 ETO16603.1 - 7.3 5.1 12.0 36 2.8 7.8 1.9 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein LmjF365940-deam PF14421.1 ETO16604.1 - 6e-47 159.5 0.0 1.3e-46 158.4 0.0 1.5 1 0 0 1 1 1 1 A distinct subfamily of CDD/CDA-like deaminases dCMP_cyt_deam_1 PF00383.17 ETO16604.1 - 0.01 15.4 0.0 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region TRAP_alpha PF03896.11 ETO16605.1 - 1.9 7.4 5.0 2.7 6.9 3.4 1.3 1 1 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF912 PF06024.7 ETO16605.1 - 2.4 8.2 5.6 1.4 9.0 2.0 1.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) zf-RanBP PF00641.13 ETO16606.1 - 2.5e-08 32.8 2.9 5.4e-08 31.8 2.0 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others PUB PF09409.5 ETO16606.1 - 5.3e-07 29.3 0.0 1.5e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 PUB domain RHH_2 PF03693.9 ETO16606.1 - 0.017 15.3 2.3 0.61 10.2 0.0 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0156) WD40 PF00400.27 ETO16607.1 - 2.9e-12 45.9 1.2 3.1e-11 42.6 0.2 2.4 2 1 0 2 2 2 1 WD domain, G-beta repeat DUF1299 PF06975.6 ETO16607.1 - 0.032 14.0 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1299) Nup160 PF11715.3 ETO16607.1 - 0.051 11.6 0.0 0.054 11.6 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 CHZ PF09649.5 ETO16607.1 - 0.39 9.9 2.1 0.68 9.2 1.5 1.4 1 0 0 1 1 1 0 Histone chaperone domain CHZ Sulfotransfer_1 PF00685.22 ETO16608.1 - 6.8e-08 32.0 0.0 8.8e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain DNA_PPF PF02916.10 ETO16608.1 - 0.083 12.9 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase processivity factor Sulfotransfer_3 PF13469.1 ETO16609.1 - 0.046 14.6 0.3 0.046 14.6 0.2 2.0 2 1 0 2 2 2 0 Sulfotransferase family ECIST_Cterm PF14784.1 ETO16610.1 - 0.052 13.4 0.2 0.052 13.4 0.1 2.9 1 1 2 3 3 3 0 C-terminal domain of the ECSIT protein Pkinase PF00069.20 ETO16610.1 - 0.1 11.7 1.3 0.19 10.8 0.9 1.3 1 0 0 1 1 1 0 Protein kinase domain DUF1395 PF07160.7 ETO16610.1 - 0.1 12.0 6.3 0.14 11.6 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) Pkinase PF00069.20 ETO16611.1 - 3.9e-53 180.2 0.0 5.2e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO16611.1 - 6.9e-26 90.8 0.0 9.3e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 ETO16611.1 - 2.3e-06 28.0 1.7 3.5e-06 27.4 1.2 1.3 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 ETO16611.1 - 0.00083 18.3 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETO16611.1 - 0.011 14.8 0.0 0.023 13.7 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO16611.1 - 0.091 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 ETO16612.1 - 6.4e-26 91.0 0.2 9.9e-20 70.7 0.1 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO16612.1 - 0.02 13.9 0.0 0.034 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 ETO16612.1 - 0.094 12.0 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase PF00069.20 ETO16613.1 - 0.021 13.9 0.5 0.065 12.3 0.0 1.8 2 0 0 2 2 2 0 Protein kinase domain TPR_12 PF13424.1 ETO16614.1 - 4.9e-07 29.5 2.8 9.6e-07 28.6 0.8 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO16614.1 - 0.00083 19.1 5.6 0.0011 18.6 0.2 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO16614.1 - 0.0036 16.9 3.8 0.0055 16.3 0.1 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO16614.1 - 0.0064 16.2 1.2 0.021 14.6 0.0 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO16614.1 - 0.0066 16.8 1.3 0.022 15.1 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO16614.1 - 0.0077 15.7 3.0 0.0081 15.7 0.1 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO16614.1 - 0.016 14.8 4.7 0.43 10.2 0.0 2.9 2 1 0 2 2 2 0 TPR repeat DUF1394 PF07159.7 ETO16615.1 - 8.4e-31 107.2 6.4 1e-28 100.3 4.4 2.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1394) Thiolase_C PF02803.13 ETO16615.1 - 0.023 14.1 0.3 0.058 12.8 0.0 1.8 2 0 0 2 2 2 0 Thiolase, C-terminal domain TRAM_LAG1_CLN8 PF03798.11 ETO16615.1 - 0.034 13.6 3.1 0.058 12.9 2.1 1.3 1 0 0 1 1 1 0 TLC domain DUF1635 PF07795.6 ETO16616.1 - 0.04 13.2 0.5 0.057 12.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF2361 PF10153.4 ETO16616.1 - 0.069 13.3 1.1 10 6.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2361) DAO PF01266.19 ETO16617.1 - 7.4e-18 64.5 0.0 9.1e-11 41.2 0.0 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.17 ETO16617.1 - 2.1e-08 33.4 0.1 0.0039 16.1 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox PF00070.22 ETO16617.1 - 3e-08 33.9 0.4 7.1e-05 23.1 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETO16617.1 - 6.9e-07 29.2 1.1 4e-06 26.7 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETO16617.1 - 8e-06 25.8 0.1 6.1e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 ETO16617.1 - 6e-05 22.7 0.1 9e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 ETO16617.1 - 0.00012 21.1 0.0 0.00034 19.5 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 ETO16617.1 - 0.00017 21.6 0.0 0.00067 19.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETO16617.1 - 0.00021 19.9 0.2 0.0035 15.8 0.1 2.4 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.14 ETO16617.1 - 0.0003 19.9 0.1 0.00062 18.9 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.1 ETO16617.1 - 0.00031 20.9 0.1 0.0006 20.0 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Thi4 PF01946.12 ETO16617.1 - 0.00034 19.7 0.1 0.00085 18.4 0.1 1.6 2 0 0 2 2 2 1 Thi4 family ApbA PF02558.11 ETO16617.1 - 0.00043 19.7 0.0 0.00094 18.6 0.0 1.6 2 0 0 2 2 1 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 ETO16617.1 - 0.0013 18.1 0.4 0.0022 17.3 0.3 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 ETO16617.1 - 0.0065 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.16 ETO16617.1 - 0.0099 15.4 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Saccharop_dh PF03435.13 ETO16617.1 - 0.02 13.8 0.0 0.036 13.0 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase Shikimate_DH PF01488.15 ETO16617.1 - 0.043 13.9 0.0 0.09 12.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1188 PF06690.6 ETO16617.1 - 0.046 12.8 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) GMC_oxred_N PF00732.14 ETO16617.1 - 0.057 12.5 0.0 3.5 6.6 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase FAD_oxidored PF12831.2 ETO16617.1 - 0.063 12.3 0.6 0.1 11.6 0.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_2 PF03446.10 ETO16617.1 - 0.094 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_9 PF13454.1 ETO16617.1 - 0.15 11.8 0.1 0.43 10.3 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Rossmann-like PF10727.4 ETO16617.1 - 0.16 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Rossmann-like domain Trp_halogenase PF04820.9 ETO16617.1 - 0.33 9.5 1.9 0.34 9.5 0.3 1.7 2 0 0 2 2 2 0 Tryptophan halogenase tRNA-synt_1c PF00749.16 ETO16619.1 - 0.071 11.7 0.2 0.086 11.4 0.1 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain PAH PF02671.16 ETO16620.1 - 1.5e-09 37.3 0.9 4.3e-09 35.8 0.3 2.0 2 0 0 2 2 2 1 Paired amphipathic helix repeat Mito_fiss_reg PF05308.6 ETO16620.1 - 0.13 11.6 1.2 0.22 10.8 0.8 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator ACBP PF00887.14 ETO16620.1 - 0.13 11.9 0.2 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 Acyl CoA binding protein Atg14 PF10186.4 ETO16621.1 - 0.59 9.0 6.1 0.56 9.1 4.2 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ADIP PF11559.3 ETO16621.1 - 0.94 9.3 7.4 0.99 9.2 5.2 1.0 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF2951 PF11166.3 ETO16621.1 - 1.6 8.5 7.8 1.9 8.3 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) DUF3959 PF13105.1 ETO16621.1 - 3.1 7.0 8.9 3.2 6.9 6.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) XhlA PF10779.4 ETO16621.1 - 3.7 7.5 9.6 4.2 7.3 6.7 1.0 1 0 0 1 1 1 0 Haemolysin XhlA PEARLI-4 PF05278.7 ETO16621.1 - 4.1 6.7 9.3 4.1 6.6 6.5 1.0 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF724 PF05266.9 ETO16621.1 - 8 6.0 9.9 8.9 5.8 6.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF724) WD40 PF00400.27 ETO16623.1 - 1.7e-11 43.5 7.0 2.1e-10 40.0 0.7 2.6 2 1 0 2 2 2 2 WD domain, G-beta repeat RPEL PF02755.10 ETO16624.1 - 9.8e-09 34.2 5.8 0.0022 17.2 0.8 4.4 4 0 0 4 4 4 3 RPEL repeat RdRP PF05183.7 ETO16625.1 - 1.5e-37 129.6 0.8 7e-37 127.3 0.1 2.3 2 1 0 2 2 2 1 RNA dependent RNA polymerase Ras PF00071.17 ETO16629.1 - 5.2e-37 126.7 0.0 3.8e-34 117.4 0.0 2.6 1 1 0 1 1 1 1 Ras family Miro PF08477.8 ETO16629.1 - 3.4e-16 59.8 0.0 2.2e-15 57.2 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO16629.1 - 1.1e-09 37.7 0.0 2.1e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETO16629.1 - 3.6e-07 29.5 0.0 1.3e-06 27.7 0.0 1.9 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 ETO16629.1 - 4e-05 23.1 0.0 0.00013 21.4 0.0 1.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 ETO16629.1 - 4e-05 23.5 0.0 0.00016 21.6 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_24 PF13479.1 ETO16629.1 - 0.00093 18.8 0.4 0.74 9.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 ETO16629.1 - 0.0068 15.6 0.0 0.014 14.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 ETO16629.1 - 0.067 13.3 0.1 0.37 10.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 ETO16629.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 ETO16629.1 - 1.6 9.0 8.6 30 4.9 4.1 3.2 3 1 0 3 3 3 0 AAA domain Sugarporin_N PF11471.3 ETO16630.1 - 0.019 14.6 0.8 0.019 14.6 0.6 2.2 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension DUF1395 PF07160.7 ETO16630.1 - 0.051 13.0 3.6 0.1 12.1 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) IncA PF04156.9 ETO16630.1 - 2 7.9 7.0 2.3 7.7 3.8 1.7 2 0 0 2 2 2 0 IncA protein LON PF02190.11 ETO16630.1 - 3.4 7.2 5.7 1.3 8.6 1.9 1.9 1 1 1 2 2 2 0 ATP-dependent protease La (LON) domain AIG1 PF04548.11 ETO16630.1 - 9.2 5.3 7.2 1.5 7.8 1.1 2.2 1 1 1 3 3 3 0 AIG1 family Pkinase PF00069.20 ETO16631.1 - 6.8e-53 179.4 0.1 8.7e-53 179.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO16631.1 - 1.3e-29 103.1 0.0 1.6e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO16631.1 - 0.0003 19.9 0.1 0.00042 19.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SCP2_2 PF13530.1 ETO16631.1 - 0.0027 17.1 0.0 0.004 16.5 0.0 1.2 1 0 0 1 1 1 1 Sterol carrier protein domain APH PF01636.18 ETO16631.1 - 0.034 13.8 0.0 0.78 9.4 0.0 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family NPR3 PF03666.8 ETO16632.1 - 0.0095 14.5 8.2 0.012 14.2 5.7 1.2 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 CobT PF06213.7 ETO16632.1 - 0.039 13.0 20.9 0.049 12.7 14.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Zip PF02535.17 ETO16632.1 - 0.12 11.3 2.5 0.14 11.1 1.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Menin PF05053.8 ETO16632.1 - 0.16 10.0 5.2 0.16 10.1 3.6 1.1 1 0 0 1 1 1 0 Menin Pox_Ag35 PF03286.9 ETO16632.1 - 0.45 10.0 15.5 0.66 9.4 10.8 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Daxx PF03344.10 ETO16632.1 - 0.79 8.1 23.7 0.93 7.9 16.4 1.0 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 ETO16632.1 - 1.1 7.1 14.8 1.2 7.0 10.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 ETO16632.1 - 2.9 5.6 24.2 3.2 5.5 16.8 1.0 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.2 ETO16632.1 - 3.1 5.3 15.5 3.1 5.3 10.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1510 PF07423.6 ETO16632.1 - 3.9 6.7 21.1 5.4 6.3 14.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Tim54 PF11711.3 ETO16632.1 - 4.4 5.7 7.4 5.1 5.5 5.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 adh_short PF00106.20 ETO16634.1 - 1.8e-09 37.7 0.0 1.9e-09 37.6 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETO16634.1 - 7e-07 29.2 0.0 7.4e-07 29.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETO16634.1 - 0.00044 19.9 0.0 0.00045 19.9 0.0 1.0 1 0 0 1 1 1 1 KR domain Glyco_tran_WecB PF03808.8 ETO16634.1 - 0.0012 18.2 0.0 0.0012 18.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase WecB/TagA/CpsF family PcrB PF01884.12 ETO16634.1 - 0.049 12.8 0.0 0.061 12.5 0.0 1.1 1 0 0 1 1 1 0 PcrB family DNA_primase_S PF01896.14 ETO16634.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase small subunit Saccharop_dh PF03435.13 ETO16634.1 - 0.11 11.5 0.0 0.11 11.4 0.0 1.0 1 0 0 1 1 1 0 Saccharopine dehydrogenase Transposase_28 PF04195.7 ETO16635.1 - 0.1 11.8 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Putative gypsy type transposon Methyltransf_23 PF13489.1 ETO16636.1 - 1.1e-08 34.9 0.0 1.8e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETO16636.1 - 2.6e-08 34.1 0.4 2.3e-07 31.0 0.3 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO16636.1 - 6.7e-08 32.9 0.1 7.1e-07 29.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETO16636.1 - 2.3e-06 28.0 0.0 5.7e-05 23.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 ETO16636.1 - 1.4e-05 24.5 0.0 6.2e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_31 PF13847.1 ETO16636.1 - 1.9e-05 24.3 0.1 0.028 13.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 ETO16636.1 - 4.4e-05 24.0 0.0 0.00017 22.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.11 ETO16636.1 - 0.00041 19.3 0.1 0.67 8.7 0.0 2.6 3 0 0 3 3 3 2 mRNA capping enzyme NodS PF05401.6 ETO16636.1 - 0.0076 15.6 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Nodulation protein S (NodS) tRNA-synt_2b PF00587.20 ETO16636.1 - 0.052 13.1 0.3 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) WD40 PF00400.27 ETO16639.1 - 4.1e-63 207.1 22.8 4.2e-12 45.4 0.2 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO16639.1 - 1.1e-11 43.5 2.2 0.11 10.5 0.0 4.6 2 1 1 4 4 4 4 Nucleoporin Nup120/160 HAD PF12710.2 ETO16639.1 - 0.28 11.3 3.2 7.1 6.7 0.0 3.3 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Alpha-amylase PF00128.19 ETO16640.1 - 0.16 11.3 3.9 0.044 13.1 0.8 1.4 2 0 0 2 2 2 0 Alpha amylase, catalytic domain DUF4217 PF13959.1 ETO16641.1 - 1e-05 24.9 0.0 2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) DEAD PF00270.24 ETO16642.1 - 1e-39 135.7 0.0 1.9e-39 134.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETO16642.1 - 1.1e-13 50.7 0.0 4.1e-13 49.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETO16642.1 - 0.00012 21.9 0.0 0.00012 21.9 0.0 2.5 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 ETO16642.1 - 0.0011 17.8 0.0 0.0017 17.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Atrophin-1 PF03154.10 ETO16642.1 - 1.2 7.1 3.5 1.6 6.7 2.4 1.1 1 0 0 1 1 1 0 Atrophin-1 family WD40 PF00400.27 ETO16644.1 - 5.6e-46 152.8 13.1 8.2e-12 44.5 0.2 5.9 6 1 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO16644.1 - 1.5e-08 33.3 0.9 0.12 10.4 0.0 4.4 1 1 3 4 4 4 3 Nucleoporin Nup120/160 DUF851 PF05867.6 ETO16644.1 - 0.0019 17.4 0.0 0.69 9.1 0.0 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF851) Glyco_hydro_98C PF08307.6 ETO16645.1 - 0.051 12.8 0.3 0.074 12.3 0.2 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 98 C-terminal domain BAF1_ABF1 PF04684.8 ETO16645.1 - 0.058 12.2 14.4 0.071 11.9 10.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Tau95 PF09734.4 ETO16645.1 - 0.068 12.4 10.8 0.085 12.1 7.5 1.1 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit DUF3984 PF13136.1 ETO16645.1 - 0.083 12.0 11.0 0.11 11.6 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) DUF3959 PF13105.1 ETO16645.1 - 0.5 9.6 9.7 0.94 8.7 6.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Neur_chan_memb PF02932.11 ETO16645.1 - 1.1 9.0 4.5 1.1 9.0 3.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF971 PF06155.7 ETO16645.1 - 1.2 9.5 4.6 2.9 8.3 3.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF971) FAM60A PF15396.1 ETO16645.1 - 1.7 8.3 11.8 2.5 7.7 8.2 1.3 1 0 0 1 1 1 0 Protein Family FAM60A DUF2217 PF10265.4 ETO16645.1 - 2.5 6.7 11.0 3.1 6.4 7.6 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Corona_nucleoca PF00937.13 ETO16645.1 - 2.7 6.8 20.4 3.5 6.4 13.8 1.4 1 1 0 1 1 1 0 Coronavirus nucleocapsid protein PPR_2 PF13041.1 ETO16648.1 - 6.6e-11 42.0 3.6 4.6e-09 36.1 0.3 2.8 2 1 1 3 3 3 2 PPR repeat family PPR PF01535.15 ETO16648.1 - 1.3e-07 31.1 0.2 0.004 17.0 0.0 2.7 2 0 0 2 2 2 2 PPR repeat PPR_3 PF13812.1 ETO16648.1 - 9.2e-06 25.5 0.0 0.027 14.7 0.0 2.8 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 ETO16648.1 - 1.8e-05 24.1 4.4 0.00069 19.0 0.0 2.8 3 0 0 3 3 3 2 PPR repeat F-box-like_2 PF13013.1 ETO16648.1 - 0.11 12.2 0.5 0.29 10.8 0.1 2.0 2 1 0 2 2 2 0 F-box-like domain MNE1 PF13762.1 ETO16648.1 - 0.13 12.3 6.1 0.043 13.8 1.9 2.0 2 1 0 2 2 2 0 Mitochondrial splicing apparatus component Trypan_PARP PF05887.6 ETO16650.1 - 3.4e-06 26.9 14.4 6.2e-06 26.0 10.0 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) NESP55 PF06390.7 ETO16650.1 - 0.00063 19.2 14.7 0.0011 18.3 10.2 1.4 1 0 0 1 1 1 1 Neuroendocrine-specific golgi protein P55 (NESP55) TMC PF07810.8 ETO16650.1 - 0.085 13.2 0.9 0.2 12.1 0.6 1.6 1 0 0 1 1 1 0 TMC domain Neisseria_TspB PF05616.8 ETO16650.1 - 2 6.7 7.5 2.7 6.2 5.2 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein WD40 PF00400.27 ETO16651.1 - 1.4e-78 256.1 14.4 8.3e-13 47.6 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO16651.1 - 3.1e-09 36.8 0.2 4.7e-06 26.4 0.1 2.7 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO16651.1 - 7.6e-07 27.6 8.5 0.038 12.1 0.1 4.8 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO16651.1 - 5.3e-06 24.9 4.5 0.059 11.6 0.1 3.1 2 1 1 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO16651.1 - 4.5e-05 22.3 3.4 1.1 7.9 0.2 4.4 1 1 2 3 3 3 3 Nup133 N terminal like Resistin PF06954.6 ETO16651.1 - 6.4e-05 23.1 0.3 4.6 7.5 0.1 4.9 4 1 1 5 5 5 1 Resistin Hira PF07569.6 ETO16651.1 - 0.0016 17.7 0.1 1.3 8.1 0.0 3.5 2 1 1 3 3 3 1 TUP1-like enhancer of split PD40 PF07676.7 ETO16651.1 - 0.0022 17.6 3.5 4.5 7.0 0.0 5.0 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO16651.1 - 0.0051 16.2 0.0 0.026 13.9 0.0 2.1 1 1 1 2 2 2 1 PQQ-like domain GATase PF00117.23 ETO16651.1 - 0.091 12.2 0.0 8.9 5.7 0.0 2.3 2 0 0 2 2 2 0 Glutamine amidotransferase class-I zf-TRAF PF02176.13 ETO16652.1 - 1.7e-05 25.1 0.5 1.7e-05 25.1 0.3 2.7 3 1 1 4 4 4 1 TRAF-type zinc finger YojJ PF10372.4 ETO16652.1 - 0.014 15.2 0.2 0.05 13.4 0.1 2.0 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus TEX19 PF15553.1 ETO16652.1 - 0.034 14.0 0.2 0.065 13.1 0.1 1.5 1 0 0 1 1 1 0 Testis-expressed protein 19 ZZ PF00569.12 ETO16652.1 - 0.044 13.3 0.3 0.12 11.9 0.2 1.7 1 0 0 1 1 1 0 Zinc finger, ZZ type zf-BED PF02892.10 ETO16652.1 - 0.23 11.2 5.5 3.2 7.5 0.1 3.5 3 0 0 3 3 3 0 BED zinc finger DUF972 PF06156.8 ETO16652.1 - 0.88 9.9 8.0 1.1 9.6 4.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF3166 PF11365.3 ETO16652.1 - 0.88 10.0 3.6 5.2 7.5 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) WD40 PF00400.27 ETO16653.1 - 3.7e-60 197.8 26.8 1e-10 41.0 0.5 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO16653.1 - 1.9e-06 26.3 4.3 0.34 8.9 0.0 4.8 1 1 3 4 4 4 4 Nucleoporin Nup120/160 WD40 PF00400.27 ETO16654.1 - 5.3e-10 38.7 1.4 8.5e-09 34.9 0.2 2.3 2 1 0 2 2 2 2 WD domain, G-beta repeat Mga PF05043.8 ETO16655.1 - 0.097 12.9 0.3 0.097 12.9 0.2 2.9 4 0 0 4 4 4 0 Mga helix-turn-helix domain BLOC1_2 PF10046.4 ETO16655.1 - 2.1 8.5 23.3 0.1 12.7 0.8 5.0 5 1 0 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UBN2_3 PF14244.1 ETO16655.1 - 2.4 7.7 9.5 0.14 11.7 1.3 2.6 2 2 1 3 3 3 0 gag-polypeptide of LTR copia-type DDE_Tnp_IS240 PF13610.1 ETO16655.1 - 2.9 7.8 8.6 2.5 8.0 0.3 3.2 1 1 2 3 3 3 0 DDE domain DASH_Dam1 PF08653.5 ETO16655.1 - 5.6 6.8 14.2 7 6.5 0.0 5.5 6 1 1 7 7 7 0 DASH complex subunit Dam1 Fib_alpha PF08702.5 ETO16655.1 - 5.8 7.0 27.4 1.4 8.9 7.2 3.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Phage_GP20 PF06810.6 ETO16656.1 - 0.0024 17.3 38.6 0.0076 15.6 15.7 2.2 1 1 1 2 2 2 2 Phage minor structural protein GP20 DUF940 PF06082.6 ETO16656.1 - 1.3 7.4 7.5 1.5 7.3 5.2 1.1 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) PolyA_pol PF01743.15 ETO16656.1 - 5 7.3 12.4 2.9 8.1 2.1 2.3 1 1 1 2 2 2 0 Poly A polymerase head domain CAP_GLY PF01302.20 ETO16657.1 - 8.1e-11 41.4 0.2 1.5e-10 40.6 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain SAM_1 PF00536.25 ETO16657.1 - 1.8e-10 40.8 0.0 3.7e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO16657.1 - 5e-06 26.2 0.0 1.2e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) NOA36 PF06524.7 ETO16657.1 - 5.5 6.1 17.6 13 4.9 12.2 1.6 1 0 0 1 1 1 0 NOA36 protein WD40 PF00400.27 ETO16658.1 - 9.1e-14 50.7 3.6 9.7e-06 25.2 0.1 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat Imm38 PF15599.1 ETO16658.1 - 0.037 13.5 0.8 0.063 12.8 0.6 1.4 1 0 0 1 1 1 0 Immunity protein 38 SURF2 PF05477.6 ETO16658.1 - 0.089 11.9 8.6 0.13 11.3 5.9 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CDC45 PF02724.9 ETO16658.1 - 0.093 10.7 6.8 0.1 10.6 4.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3245 PF11595.3 ETO16658.1 - 0.34 11.1 8.0 0.53 10.5 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Nucleo_P87 PF07267.6 ETO16658.1 - 0.61 8.7 5.2 0.76 8.3 3.6 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Nucleoplasmin PF03066.10 ETO16658.1 - 1.2 8.5 6.6 1.9 7.9 4.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 ETO16658.1 - 1.4 8.6 10.2 40 3.9 6.6 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal HORMA PF02301.13 ETO16659.1 - 1.6e-13 50.6 0.1 2.2e-13 50.1 0.1 1.2 1 0 0 1 1 1 1 HORMA domain CUE PF02845.11 ETO16660.1 - 0.15 11.5 0.0 0.15 11.5 0.0 3.0 2 1 0 2 2 2 0 CUE domain PAT1 PF09770.4 ETO16660.1 - 1.4 7.0 24.5 1.7 6.8 17.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Activator_LAG-3 PF11498.3 ETO16660.1 - 3.7 6.2 31.1 5.1 5.7 21.6 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TFIIA PF03153.8 ETO16660.1 - 3.8 7.2 15.6 4.6 7.0 10.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.5 ETO16660.1 - 9.5 4.2 37.6 11 4.0 26.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Kelch_1 PF01344.20 ETO16661.1 - 4.1e-05 23.0 0.9 0.0016 17.9 0.6 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.10 ETO16661.1 - 0.00033 20.2 0.4 0.046 13.5 0.2 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.1 ETO16661.1 - 0.0044 17.1 2.0 0.29 11.3 0.4 2.4 1 1 1 2 2 2 2 Kelch motif Kelch_4 PF13418.1 ETO16661.1 - 0.011 15.5 0.8 1.8 8.3 0.2 2.9 1 1 1 2 2 2 0 Galactose oxidase, central domain TLD PF07534.11 ETO16661.1 - 0.05 13.5 0.4 0.087 12.8 0.2 1.4 1 1 0 1 1 1 0 TLD Ion_trans PF00520.26 ETO16662.1 - 0.0012 18.1 2.4 0.0012 18.1 1.6 1.9 2 0 0 2 2 2 1 Ion transport protein TraP PF07296.6 ETO16662.1 - 0.18 10.7 0.7 4.9 6.0 0.1 2.4 1 1 1 2 2 2 0 TraP protein WD40 PF00400.27 ETO16665.1 - 1.6e-12 46.7 5.1 6.3e-11 41.7 1.2 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO16665.1 - 1.2e-05 23.7 0.1 1.3e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO16665.1 - 0.028 13.7 0.4 0.04 13.2 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4221) Asp PF00026.18 ETO16666.1 - 2.5e-07 30.2 0.0 2.5e-07 30.2 0.0 1.9 2 1 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETO16666.1 - 1.3e-05 25.2 0.1 1.3e-05 25.2 0.1 2.2 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 ETO16666.1 - 7e-05 22.4 0.0 0.00025 20.6 0.0 1.9 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal SPX PF03105.14 ETO16666.1 - 0.096 12.4 9.3 0.071 12.8 0.4 2.1 1 1 0 2 2 2 0 SPX domain Methyltransf_12 PF08242.7 ETO16666.1 - 0.17 12.3 11.2 3.4 8.2 2.4 3.1 3 1 0 3 3 3 0 Methyltransferase domain Claudin_2 PF13903.1 ETO16666.1 - 0.21 11.2 6.5 0.29 10.8 0.8 2.3 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF912 PF06024.7 ETO16666.1 - 0.28 11.2 11.5 0.19 11.7 0.8 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pex14_N PF04695.8 ETO16666.1 - 2.5 8.1 8.4 0.39 10.7 0.5 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Eapp_C PF10238.4 ETO16666.1 - 2.8 7.8 19.6 1.4 8.8 5.1 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein TAXi_N PF14543.1 ETO16667.1 - 6.8e-07 29.3 8.3 1.2e-06 28.6 5.8 1.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.18 ETO16667.1 - 4.2e-06 26.2 0.0 6e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Menin PF05053.8 ETO16667.1 - 0.014 13.5 1.5 0.014 13.6 1.0 1.1 1 0 0 1 1 1 0 Menin zf-FCS PF06467.9 ETO16667.1 - 3.3 7.4 10.3 8.8 6.0 7.1 1.8 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif TLP-20 PF06088.6 ETO16668.1 - 0.015 14.9 2.0 0.015 14.9 1.4 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF4304 PF14137.1 ETO16668.1 - 2.9 8.0 7.3 4.5 7.4 5.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4304) EzrA PF06160.7 ETO16669.1 - 0.00076 17.7 8.6 0.00091 17.5 6.0 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Transposase_22 PF02994.9 ETO16669.1 - 0.0052 15.3 6.2 0.0063 15.0 4.3 1.1 1 0 0 1 1 1 1 L1 transposable element DUF724 PF05266.9 ETO16669.1 - 0.023 14.3 6.6 0.032 13.8 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4254 PF14063.1 ETO16669.1 - 0.044 13.3 0.2 0.056 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) DUF342 PF03961.8 ETO16669.1 - 0.061 11.7 7.7 0.071 11.5 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FTA4 PF13093.1 ETO16669.1 - 0.067 12.6 6.9 0.052 12.9 3.7 1.4 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 EFhand_Ca_insen PF08726.5 ETO16669.1 - 0.096 12.6 2.4 0.19 11.6 1.7 1.6 1 0 0 1 1 1 0 Ca2+ insensitive EF hand Jnk-SapK_ap_N PF09744.4 ETO16669.1 - 0.14 12.1 10.6 0.21 11.5 7.3 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DivIC PF04977.10 ETO16669.1 - 1.3 8.6 6.8 0.61 9.6 1.3 2.5 1 1 2 3 3 3 0 Septum formation initiator IncA PF04156.9 ETO16669.1 - 1.5 8.4 8.1 1.9 8.0 5.6 1.2 1 0 0 1 1 1 0 IncA protein WEMBL PF05701.6 ETO16670.1 - 0.0019 16.7 13.4 0.0026 16.2 9.3 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Phage_lysis PF03245.8 ETO16670.1 - 0.023 14.6 2.4 0.026 14.5 0.2 2.0 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein Rop-like PF05082.8 ETO16670.1 - 0.037 13.4 3.2 0.066 12.6 2.0 1.6 1 1 0 1 1 1 0 Rop-like SlyX PF04102.7 ETO16670.1 - 0.06 13.7 0.6 0.06 13.7 0.4 3.3 2 2 1 3 3 3 0 SlyX MIS13 PF08202.6 ETO16670.1 - 0.12 11.3 13.2 0.15 11.1 9.1 1.2 1 0 0 1 1 1 0 Mis12-Mtw1 protein family FUSC PF04632.7 ETO16670.1 - 0.13 10.6 1.5 0.15 10.4 1.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family EDR1 PF14381.1 ETO16670.1 - 0.18 11.3 1.7 0.27 10.7 0.2 1.9 1 1 1 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 PdxJ PF03740.8 ETO16670.1 - 0.18 10.9 1.8 1.6 7.8 0.2 2.2 1 1 1 2 2 2 0 Pyridoxal phosphate biosynthesis protein PdxJ HisKA_2 PF07568.7 ETO16670.1 - 0.38 10.6 2.5 0.49 10.2 0.4 2.3 2 1 0 2 2 2 0 Histidine kinase V_ATPase_I PF01496.14 ETO16670.1 - 0.52 8.0 6.8 0.59 7.9 4.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cob_adeno_trans PF01923.13 ETO16670.1 - 1.1 9.0 4.6 1.1 9.0 1.7 2.0 1 1 2 3 3 3 0 Cobalamin adenosyltransferase Filament PF00038.16 ETO16670.1 - 1.4 8.3 14.6 0.2 11.0 5.8 1.9 1 1 0 2 2 2 0 Intermediate filament protein FliD_N PF02465.13 ETO16670.1 - 1.4 9.2 14.8 0.16 12.3 1.3 3.3 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus TBPIP PF07106.8 ETO16670.1 - 1.6 8.2 16.7 3.9 6.9 0.1 3.1 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Bap31 PF05529.7 ETO16670.1 - 2.1 7.7 12.7 8.3 5.8 5.9 2.6 1 1 2 3 3 3 0 B-cell receptor-associated protein 31-like DUF342 PF03961.8 ETO16670.1 - 2.2 6.6 8.0 3.6 5.9 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Spc42p PF11544.3 ETO16670.1 - 2.5 8.0 13.0 0.28 11.1 4.5 2.6 2 1 1 3 3 3 0 Spindle pole body component Spc42p DUF3450 PF11932.3 ETO16670.1 - 2.7 7.1 14.7 0.17 11.1 5.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) DUF4201 PF13870.1 ETO16670.1 - 2.8 7.3 17.3 0.85 9.0 8.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) MscS_porin PF12795.2 ETO16670.1 - 2.9 7.1 18.5 1.2 8.4 6.1 2.7 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Ly49 PF08391.5 ETO16670.1 - 2.9 8.0 7.2 1 9.4 3.0 1.7 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region Laminin_II PF06009.7 ETO16670.1 - 3.8 7.2 11.0 1.2 8.9 3.3 2.1 2 0 0 2 2 2 0 Laminin Domain II IncA PF04156.9 ETO16670.1 - 4.2 6.9 14.2 1.5e+02 1.8 10.2 2.1 1 1 0 1 1 1 0 IncA protein Allexi_40kDa PF05549.6 ETO16670.1 - 5.9 6.0 9.8 2.8 7.1 2.1 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF2877 PF11392.3 ETO16671.1 - 0.043 14.0 0.6 0.25 11.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2877) Serinc PF03348.10 ETO16673.1 - 4.7e-05 22.2 0.2 6e-05 21.9 0.2 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) CENP-B_dimeris PF09026.5 ETO16673.1 - 0.0016 18.6 1.2 0.0031 17.7 0.8 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Ycf1 PF05758.7 ETO16673.1 - 0.0017 16.2 0.2 0.0017 16.1 0.1 1.1 1 0 0 1 1 1 1 Ycf1 IncA PF04156.9 ETO16673.1 - 0.0018 17.9 0.4 0.0024 17.4 0.3 1.2 1 0 0 1 1 1 1 IncA protein DUF4446 PF14584.1 ETO16673.1 - 0.0024 17.7 0.9 0.0024 17.7 0.6 1.6 2 0 0 2 2 1 1 Protein of unknown function (DUF4446) DUF2254 PF10011.4 ETO16673.1 - 0.0029 16.1 0.4 0.0029 16.1 0.3 1.7 1 1 1 2 2 2 1 Predicted membrane protein (DUF2254) Med17 PF10156.4 ETO16673.1 - 0.0069 14.7 1.4 0.0085 14.4 0.9 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex DUF2457 PF10446.4 ETO16673.1 - 0.0079 14.9 6.2 0.01 14.6 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) FAM176 PF14851.1 ETO16673.1 - 0.0088 15.7 3.4 0.011 15.4 0.8 2.0 2 0 0 2 2 2 1 FAM176 family Effector_1 PF04518.7 ETO16673.1 - 0.012 14.6 0.3 0.014 14.3 0.2 1.1 1 0 0 1 1 1 0 Effector from type III secretion system FGF-BP1 PF06473.7 ETO16673.1 - 0.013 15.1 1.1 0.017 14.7 0.8 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) DUF1510 PF07423.6 ETO16673.1 - 0.013 14.8 13.4 0.02 14.2 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF912 PF06024.7 ETO16673.1 - 0.014 15.3 0.7 0.19 11.7 0.0 2.3 1 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Folate_carrier PF01770.13 ETO16673.1 - 0.015 13.8 0.9 0.019 13.4 0.7 1.1 1 0 0 1 1 1 0 Reduced folate carrier Neur_chan_memb PF02932.11 ETO16673.1 - 0.024 14.5 0.1 0.03 14.2 0.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2500 PF10694.4 ETO16673.1 - 0.028 14.4 4.3 0.025 14.5 2.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2500) OSTbeta PF15048.1 ETO16673.1 - 0.039 14.0 0.5 0.063 13.3 0.4 1.4 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF106 PF01956.11 ETO16673.1 - 0.046 13.2 0.3 0.068 12.6 0.2 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF106 BTV_NS2 PF04514.7 ETO16673.1 - 0.05 12.4 5.1 0.066 12.0 3.5 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Sec62 PF03839.11 ETO16673.1 - 0.057 12.8 2.9 0.089 12.1 2.0 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 AIF_C PF14721.1 ETO16673.1 - 0.087 13.0 1.7 0.13 12.4 1.2 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Astro_capsid PF03115.9 ETO16673.1 - 0.13 10.4 1.9 0.16 10.1 1.3 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF3899 PF13038.1 ETO16673.1 - 0.15 12.2 3.4 0.16 12.1 0.1 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF3899) DUF2215 PF10225.4 ETO16673.1 - 0.32 10.3 4.4 1.8 7.9 0.4 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) TRAP_alpha PF03896.11 ETO16673.1 - 0.33 9.9 5.4 0.46 9.4 3.7 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RNA_pol_3_Rpc31 PF11705.3 ETO16673.1 - 0.5 10.2 15.4 0.77 9.6 10.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2681 PF10883.3 ETO16673.1 - 0.51 10.5 6.5 1.5 9.0 4.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) 60KD_IMP PF02096.15 ETO16673.1 - 6.8 6.3 7.6 2.1 7.9 3.0 1.8 1 1 0 1 1 1 0 60Kd inner membrane protein Mannosyl_trans2 PF04188.8 ETO16675.1 - 3.1e-20 72.5 36.0 2.6e-19 69.4 25.0 1.9 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V)) Clathrin PF00637.15 ETO16676.1 - 0.035 13.7 0.3 0.053 13.1 0.2 1.2 1 0 0 1 1 1 0 Region in Clathrin and VPS DUF2273 PF10031.4 ETO16676.1 - 0.06 12.9 0.2 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) Glyco_hydro_2_C PF02836.12 ETO16678.1 - 5.1 5.9 7.6 7.4 5.3 5.1 1.4 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Annexin PF00191.15 ETO16679.1 - 1.2e-36 124.4 0.0 1e-10 41.3 0.0 4.4 4 0 0 4 4 4 4 Annexin GATase PF00117.23 ETO16680.1 - 6.6e-12 45.2 0.2 1.6e-11 44.0 0.1 1.6 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 ETO16680.1 - 3.4e-05 23.3 0.1 9.9e-05 21.8 0.1 1.9 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 ETO16680.1 - 0.0097 15.3 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family GYF PF02213.11 ETO16683.1 - 6.5e-11 41.6 4.2 2.1e-10 40.0 2.9 1.9 1 0 0 1 1 1 1 GYF domain PDR_CDR PF06422.7 ETO16683.1 - 0.5 10.0 3.8 2.1 8.0 0.0 3.5 4 0 0 4 4 4 0 CDR ABC transporter TLD PF07534.11 ETO16684.1 - 6.5e-16 58.5 0.8 6.5e-16 58.5 0.5 2.2 2 0 0 2 2 2 1 TLD fn3 PF00041.16 ETO16684.1 - 0.00083 19.4 0.7 0.0029 17.7 0.5 2.0 1 0 0 1 1 1 1 Fibronectin type III domain DUF3753 PF12575.3 ETO16684.1 - 1.5 8.6 8.1 0.78 9.5 3.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) Ras PF00071.17 ETO16686.1 - 3.1e-15 55.9 5.1 3.7e-08 32.9 0.8 3.1 2 1 0 2 2 2 2 Ras family Miro PF08477.8 ETO16686.1 - 9.4e-08 32.5 0.0 4.1e-07 30.5 0.0 2.1 1 1 0 1 1 1 1 Miro-like protein DUF2721 PF11026.3 ETO16686.1 - 0.0064 16.1 0.0 0.016 14.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) Dynamin_N PF00350.18 ETO16686.1 - 0.16 11.8 1.2 0.87 9.3 0.0 2.4 2 0 0 2 2 2 0 Dynamin family Y_phosphatase3 PF13350.1 ETO16687.1 - 0.0011 19.2 0.0 0.0011 19.2 0.0 4.1 5 1 0 5 5 5 1 Tyrosine phosphatase family DSPc PF00782.15 ETO16687.1 - 0.0014 18.1 0.1 0.0014 18.1 0.1 4.6 5 1 1 6 6 6 1 Dual specificity phosphatase, catalytic domain McyA_C PF12593.3 ETO16687.1 - 0.047 13.4 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 Microcystin synthetase C terminal DUF2165 PF09933.4 ETO16689.1 - 0.091 12.4 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) SUKH_6 PF14568.1 ETO16689.1 - 0.16 12.4 1.2 0.22 11.9 0.5 1.5 2 0 0 2 2 2 0 SMI1-KNR4 cell-wall PIN_4 PF13638.1 ETO16690.1 - 0.08 13.0 0.4 0.18 11.9 0.3 1.6 1 0 0 1 1 1 0 PIN domain DivIVA PF05103.8 ETO16691.1 - 0.77 9.8 5.8 0.15 12.1 0.4 2.0 2 0 0 2 2 2 0 DivIVA protein DUF1295 PF06966.7 ETO16692.1 - 8.5e-42 143.0 0.1 9.4e-42 142.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 ETO16692.1 - 8.2e-07 28.8 0.3 2.6e-06 27.2 0.2 1.7 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.9 ETO16692.1 - 0.0031 17.6 0.9 0.0046 17.1 0.0 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 ETO16692.1 - 0.0045 17.0 0.2 0.0079 16.2 0.1 1.4 1 0 0 1 1 1 1 Phospholipid methyltransferase CAP_GLY PF01302.20 ETO16694.1 - 1.3e-10 40.7 0.7 2.7e-10 39.7 0.5 1.6 1 0 0 1 1 1 1 CAP-Gly domain WD40 PF00400.27 ETO16695.1 - 3.9e-46 153.3 17.4 3e-10 39.5 0.4 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO16695.1 - 5.3e-08 31.4 0.5 0.082 11.0 0.0 4.5 1 1 2 3 3 3 3 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO16695.1 - 0.00088 19.1 0.1 0.23 11.4 0.0 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF3601) WD40 PF00400.27 ETO16696.1 - 5.4e-71 232.1 18.4 3.7e-13 48.7 0.2 7.2 6 1 1 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO16696.1 - 9.4e-12 43.8 14.3 0.00064 17.9 0.6 5.2 1 1 4 5 5 5 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO16696.1 - 1.2e-10 40.2 1.3 0.0013 17.1 0.1 4.0 1 1 3 4 4 4 4 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO16696.1 - 6.4e-08 31.7 8.2 0.00028 19.7 1.6 3.2 1 1 2 3 3 3 2 Nup133 N terminal like PD40 PF07676.7 ETO16696.1 - 7.1e-08 31.9 5.8 0.083 12.5 0.0 5.3 6 0 0 6 6 6 3 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO16696.1 - 2.7e-05 23.7 3.0 8.4e-05 22.1 2.1 1.9 1 1 0 1 1 1 1 PQQ-like domain Resistin PF06954.6 ETO16696.1 - 7.2e-05 22.9 0.3 2.5 8.4 0.0 3.8 2 1 2 4 4 4 2 Resistin DPPIV_N PF00930.16 ETO16696.1 - 0.00064 18.4 1.6 0.037 12.6 0.4 3.8 1 1 2 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Ricin_B_lectin PF00652.17 ETO16696.1 - 0.013 15.5 1.7 0.23 11.5 0.1 2.9 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain DUF2677 PF10838.3 ETO16696.1 - 0.039 13.5 0.1 0.098 12.2 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2677) TFIIIC_delta PF12657.2 ETO16696.1 - 0.041 13.5 3.2 3.5 7.3 0.4 2.9 1 1 1 2 2 2 0 Transcription factor IIIC subunit delta N-term CRAL_TRIO_2 PF13716.1 ETO16696.1 - 0.091 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Rav1p_C PF12234.3 ETO16696.1 - 0.12 10.4 2.3 0.41 8.7 0.1 2.3 1 1 1 3 3 3 0 RAVE protein 1 C terminal Kelch_4 PF13418.1 ETO16697.1 - 1.9e-07 30.7 0.1 0.0013 18.5 0.0 2.9 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO16697.1 - 2.9e-07 30.3 1.7 0.0083 16.2 0.1 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO16697.1 - 8.9e-05 22.3 0.5 22 5.1 0.0 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO16697.1 - 0.00012 21.5 1.0 0.072 12.6 0.1 3.6 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO16697.1 - 0.00014 21.5 2.9 0.035 13.8 0.1 3.8 5 0 0 5 5 5 2 Kelch motif WD40 PF00400.27 ETO16698.1 - 4.2e-53 175.4 33.9 1e-09 37.9 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO16698.1 - 4.2e-08 31.7 4.6 0.0012 17.1 0.1 4.7 2 2 3 5 5 5 3 Nucleoporin Nup120/160 HAD PF12710.2 ETO16698.1 - 0.058 13.5 4.6 4.8 7.2 0.1 3.2 2 2 0 2 2 2 0 haloacid dehalogenase-like hydrolase WD40 PF00400.27 ETO16699.1 - 3.9e-65 213.5 26.3 4.9e-13 48.4 0.1 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO16699.1 - 2.2e-12 47.0 1.1 2.3e-08 33.9 0.1 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO16699.1 - 1.2e-07 30.2 3.5 0.11 10.6 0.1 4.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO16699.1 - 6.9e-07 27.8 0.3 0.025 12.8 0.0 2.4 1 1 2 3 3 3 3 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO16699.1 - 0.00011 21.8 0.1 0.00037 20.0 0.1 1.7 1 1 0 1 1 1 1 PQQ-like domain DPPIV_N PF00930.16 ETO16699.1 - 0.0025 16.4 0.0 7 5.1 0.0 3.4 1 1 2 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.7 ETO16699.1 - 0.0037 16.9 5.9 9.8 5.9 0.1 4.8 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO16699.1 - 0.0039 17.4 1.7 21 5.4 0.0 4.2 1 1 3 4 4 4 0 Resistin Ricin_B_lectin PF00652.17 ETO16699.1 - 0.024 14.6 3.9 0.3 11.1 0.5 2.6 2 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain VWA PF00092.23 ETO16700.1 - 0.001 18.8 0.0 0.083 12.5 0.1 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain Isochorismatase PF00857.15 ETO16700.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.6 2 0 0 2 2 2 0 Isochorismatase family O-antigen_lig PF13425.1 ETO16700.1 - 0.42 10.5 6.4 2.3 8.1 0.7 2.4 2 0 0 2 2 2 0 O-antigen ligase like membrane protein PT PF04886.7 ETO16700.1 - 1 8.7 6.3 2.5 7.4 4.3 1.6 1 1 0 1 1 1 0 PT repeat Laminin_G_3 PF13385.1 ETO16701.1 - 3e-07 30.8 0.0 7.8e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Daxx PF03344.10 ETO16701.1 - 0.14 10.6 19.8 0.25 9.8 13.8 1.3 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 ETO16701.1 - 0.25 10.3 17.3 0.41 9.6 12.0 1.2 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.7 ETO16701.1 - 0.31 10.7 20.3 0.67 9.6 14.1 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1510 PF07423.6 ETO16701.1 - 0.31 10.3 17.6 0.77 9.0 12.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 ETO16701.1 - 1.4 6.8 16.6 2.2 6.2 11.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Herpes_LMP1 PF05297.6 ETO16701.1 - 3.5 6.4 18.3 7.7 5.3 12.7 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Sulfatase PF00884.18 ETO16703.1 - 8.3e-44 150.0 5.4 1e-43 149.7 2.9 1.7 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 ETO16703.1 - 4.3e-08 32.8 0.0 1.5e-07 31.1 0.0 1.8 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase OAS1_C PF10421.4 ETO16704.1 - 0.0031 17.0 0.2 0.0059 16.1 0.1 1.4 1 0 0 1 1 1 1 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus WD40 PF00400.27 ETO16705.1 - 1.5e-16 59.5 2.2 7.6e-07 28.7 0.2 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat eIF2A PF08662.6 ETO16705.1 - 0.00084 19.1 0.0 0.0018 18.0 0.0 1.5 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO16705.1 - 0.0083 14.4 0.0 0.044 12.0 0.0 1.7 1 1 1 2 2 2 2 Cytochrome D1 heme domain WD40 PF00400.27 ETO16706.1 - 2.1e-72 236.6 10.5 3.6e-11 42.4 0.6 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO16706.1 - 1.6e-10 41.0 2.0 0.0013 18.4 0.0 4.4 2 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO16706.1 - 6.7e-06 24.6 7.9 0.022 13.0 0.0 4.1 2 1 3 5 5 5 4 Cytochrome D1 heme domain PD40 PF07676.7 ETO16706.1 - 0.0018 17.9 4.3 20 4.9 0.2 4.8 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO16706.1 - 0.005 16.3 4.0 2.2 7.6 0.2 3.4 3 1 1 4 4 4 2 PQQ-like domain Nbas_N PF15492.1 ETO16706.1 - 0.014 14.4 2.5 1.3 8.0 0.0 3.7 1 1 4 5 5 5 0 Neuroblastoma-amplified sequence, N terminal TFIIIC_delta PF12657.2 ETO16706.1 - 0.021 14.5 1.3 0.34 10.6 0.3 2.7 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term SWIRM PF04433.12 ETO16706.1 - 0.044 13.9 0.6 3.2 7.9 0.0 2.6 2 0 0 2 2 2 0 SWIRM domain SpoIIIAH PF12685.2 ETO16707.1 - 0.00095 18.7 0.1 0.0012 18.4 0.1 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein DUF1510 PF07423.6 ETO16707.1 - 0.0019 17.5 0.3 0.0023 17.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) DUF4512 PF14975.1 ETO16707.1 - 0.0043 17.8 0.0 0.0066 17.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4512) Kei1 PF08552.6 ETO16707.1 - 0.0051 16.5 0.0 0.0058 16.3 0.0 1.0 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 FixQ PF05545.6 ETO16707.1 - 0.0054 16.3 0.0 0.0082 15.7 0.0 1.3 1 0 0 1 1 1 1 Cbb3-type cytochrome oxidase component FixQ TRAP_alpha PF03896.11 ETO16707.1 - 0.024 13.6 0.1 0.028 13.4 0.0 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SIT PF15330.1 ETO16707.1 - 0.039 14.0 1.1 0.069 13.2 0.8 1.3 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF3139 PF11337.3 ETO16707.1 - 0.057 13.7 0.1 0.085 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) DUF3357 PF11837.3 ETO16707.1 - 0.065 13.0 0.1 0.18 11.6 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) DUF1180 PF06679.7 ETO16707.1 - 0.094 12.6 0.8 0.19 11.6 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) DUF2500 PF10694.4 ETO16707.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) DUF4131 PF13567.1 ETO16707.1 - 0.14 11.5 0.2 0.22 10.8 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) THF_DHG_CYH PF00763.18 ETO16708.1 - 1.2e-10 41.4 0.0 1.5e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain YqgF PF14639.1 ETO16708.1 - 0.021 14.3 0.1 0.025 14.1 0.1 1.1 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 WD40 PF00400.27 ETO16709.1 - 4.4e-11 42.2 0.7 6.8e-11 41.6 0.0 1.6 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF2373 PF10180.4 ETO16709.1 - 0.78 9.3 3.7 0.47 10.0 1.0 1.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2373) WD40 PF00400.27 ETO16710.1 - 4.7e-15 54.8 10.8 1.5e-06 27.8 0.2 4.1 3 1 1 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO16710.1 - 0.0027 15.9 0.9 0.25 9.4 0.1 2.8 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO16710.1 - 0.023 13.4 1.9 0.27 9.9 0.5 2.2 1 1 2 3 3 3 0 Nup133 N terminal like RRM_6 PF14259.1 ETO16711.1 - 0.0014 18.5 0.1 0.006 16.5 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO16711.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zw10 PF06248.8 ETO16711.1 - 0.016 13.4 0.2 0.022 12.9 0.1 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 RPAP3_C PF13877.1 ETO16712.1 - 0.011 15.7 0.6 0.019 14.9 0.2 1.6 1 1 0 1 1 1 0 Potential Monad-binding region of RPAP3 AAA_18 PF13238.1 ETO16712.1 - 0.059 13.6 2.1 0.066 13.5 1.4 1.1 1 0 0 1 1 1 0 AAA domain LNS2 PF08235.8 ETO16712.1 - 0.12 11.9 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) DUF2348 PF09807.4 ETO16712.1 - 0.14 11.2 1.6 5.4 6.0 0.2 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2348) EF-hand_2 PF09068.6 ETO16712.1 - 0.17 11.9 1.7 0.21 11.6 1.2 1.3 1 0 0 1 1 1 0 EF hand KilA-N PF04383.8 ETO16712.1 - 0.32 10.6 4.1 0.39 10.3 2.8 1.1 1 0 0 1 1 1 0 KilA-N domain RCC1 PF00415.13 ETO16713.1 - 6.2e-24 83.9 7.8 6.6e-07 29.4 0.0 5.8 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO16713.1 - 4.9e-14 51.4 3.4 0.0015 18.0 0.0 5.2 4 1 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat DUF3464 PF11947.3 ETO16714.1 - 0.00055 19.4 0.0 0.00089 18.7 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3464) Spore_coat_CotO PF14153.1 ETO16714.1 - 0.0028 17.1 0.1 0.0028 17.1 0.0 1.1 1 0 0 1 1 1 1 Spore coat protein CotO Kelch_6 PF13964.1 ETO16715.1 - 0.0074 16.4 0.2 0.16 12.1 0.0 2.6 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 ETO16715.1 - 0.15 12.0 0.0 0.62 10.0 0.0 2.1 2 0 0 2 2 2 0 Kelch motif HEAT_2 PF13646.1 ETO16717.1 - 1.2e-32 112.0 29.4 5.7e-11 42.5 0.8 5.3 2 1 3 5 5 5 5 HEAT repeats HEAT PF02985.17 ETO16717.1 - 3.3e-15 54.7 5.7 1.6 9.0 0.0 9.0 9 0 0 9 9 9 5 HEAT repeat HEAT_EZ PF13513.1 ETO16717.1 - 2.8e-08 33.9 18.4 0.00073 19.9 0.1 6.9 6 2 2 8 8 8 2 HEAT-like repeat HEAT_PBS PF03130.11 ETO16717.1 - 0.0001 22.4 18.4 4.5 8.0 0.2 6.4 6 0 0 6 6 6 4 PBS lyase HEAT-like repeat DUF3053 PF11254.3 ETO16717.1 - 0.02 14.1 2.1 0.041 13.1 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) Mqo PF06039.10 ETO16718.1 - 0.012 13.8 0.5 0.015 13.5 0.4 1.0 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) eIF3g PF12353.3 ETO16718.1 - 1.9 8.4 9.2 0.25 11.2 0.8 2.4 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G WD40 PF00400.27 ETO16719.1 - 7.2e-19 66.8 7.4 3.6e-10 39.3 0.1 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO16719.1 - 0.0015 16.8 5.2 0.013 13.7 0.6 2.7 2 1 0 2 2 2 2 Nucleoporin Nup120/160 PD40 PF07676.7 ETO16719.1 - 0.0016 18.0 0.2 0.4 10.4 0.0 3.4 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat eIF2A PF08662.6 ETO16719.1 - 0.016 14.9 0.1 1.4 8.5 0.0 2.9 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A DPPIV_N PF00930.16 ETO16719.1 - 0.046 12.2 0.0 0.63 8.5 0.0 2.6 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region COX5B PF01215.14 ETO16720.1 - 2.5e-12 46.6 0.0 3.7e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Med19 PF10278.4 ETO16721.1 - 0.0098 15.5 6.6 0.0098 15.5 4.6 2.9 3 0 0 3 3 3 1 Mediator of RNA pol II transcription subunit 19 Nucleoplasmin PF03066.10 ETO16721.1 - 0.013 14.9 8.9 0.013 14.9 6.2 2.9 3 0 0 3 3 3 0 Nucleoplasmin DUF1682 PF07946.9 ETO16721.1 - 0.37 9.6 18.0 0.032 13.0 8.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) DUF106 PF01956.11 ETO16721.1 - 4.6 6.7 5.5 8.6 5.8 3.8 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF106 WD40 PF00400.27 ETO16722.1 - 1.6e-52 173.5 19.4 1e-11 44.2 0.0 8.8 8 0 0 8 8 8 8 WD domain, G-beta repeat TFIID_90kDa PF04494.10 ETO16722.1 - 1.6e-16 60.7 4.2 2.8e-15 56.6 2.9 2.5 1 1 0 1 1 1 1 WD40 associated region in TFIID subunit SGL PF08450.7 ETO16722.1 - 0.02 14.2 0.1 0.15 11.3 0.0 2.0 2 0 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region MRP-S26 PF14943.1 ETO16722.1 - 0.71 9.4 4.3 0.27 10.7 0.9 1.8 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 WD40 PF00400.27 ETO16723.1 - 2.6e-39 131.7 5.8 4.1e-11 42.3 0.1 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO16723.1 - 4.9e-05 21.6 8.1 0.006 14.7 0.1 3.3 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 ETO16723.1 - 0.00026 20.4 0.3 0.16 11.5 0.0 4.0 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.9 ETO16723.1 - 0.00077 18.3 0.4 0.00077 18.3 0.3 1.5 2 0 0 2 2 2 1 Coatomer WD associated region Nucleoporin_N PF08801.6 ETO16723.1 - 0.0047 15.7 4.0 1.1 7.9 0.1 3.1 1 1 1 3 3 3 2 Nup133 N terminal like EAF PF09816.4 ETO16723.1 - 0.058 13.3 0.0 2.2 8.2 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription elongation factor Coatomer_WDAD PF04053.9 ETO16724.1 - 1.3e-85 287.8 1.6 1.7e-85 287.5 1.1 1.1 1 0 0 1 1 1 1 Coatomer WD associated region LisH PF08513.6 ETO16724.1 - 0.083 12.6 0.0 0.35 10.7 0.0 2.1 2 0 0 2 2 2 0 LisH COPI_C PF06957.6 ETO16724.1 - 1 7.7 11.8 1.5 7.3 8.2 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus COPI_C PF06957.6 ETO16725.1 - 1.6e-46 158.7 0.9 1.9e-46 158.5 0.6 1.0 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus DUF4145 PF13643.1 ETO16725.1 - 0.1 12.4 0.1 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4145) UQ_con PF00179.21 ETO16726.1 - 4.9e-51 171.8 0.0 4.9e-51 171.8 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme DUF2201_N PF13203.1 ETO16726.1 - 0.0018 17.5 9.8 0.0021 17.2 6.8 1.1 1 0 0 1 1 1 1 Putative metallopeptidase domain CobT PF06213.7 ETO16726.1 - 0.14 11.3 19.3 0.18 10.9 13.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Zip PF02535.17 ETO16726.1 - 0.15 11.0 4.4 0.17 10.8 3.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1510 PF07423.6 ETO16726.1 - 0.2 11.0 28.2 0.24 10.7 19.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ycf1 PF05758.7 ETO16726.1 - 0.24 9.0 11.4 0.25 8.9 7.9 1.0 1 0 0 1 1 1 0 Ycf1 NARP1 PF12569.3 ETO16726.1 - 0.3 9.7 14.8 0.37 9.4 10.3 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DDHD PF02862.12 ETO16726.1 - 0.6 9.8 14.3 0.81 9.4 9.9 1.1 1 0 0 1 1 1 0 DDHD domain Phyto_Pns9_10 PF05878.6 ETO16726.1 - 1.4 7.8 16.8 1.8 7.4 11.7 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 RR_TM4-6 PF06459.7 ETO16726.1 - 1.5 8.6 17.3 2.1 8.1 12.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4175 PF13779.1 ETO16726.1 - 2 5.9 15.5 2.5 5.7 10.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) GAGA_bind PF06217.7 ETO16726.1 - 6.7 6.5 15.2 8.2 6.3 10.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Med19 PF10278.4 ETO16726.1 - 9 5.9 23.3 13 5.3 16.1 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF3857 PF12969.2 ETO16727.1 - 0.013 15.1 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3857) RCC1 PF00415.13 ETO16728.1 - 1.2e-07 31.8 0.9 3e-06 27.3 0.1 2.6 2 1 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO16728.1 - 0.0021 17.6 7.0 0.011 15.2 1.4 2.9 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 ETO16729.1 - 1e-10 41.6 9.2 0.0001 22.4 0.3 5.2 5 1 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO16729.1 - 1.1e-06 28.1 15.6 0.013 15.1 0.2 3.8 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat DUF3378 PF11858.3 ETO16729.1 - 0.49 10.4 6.3 0.37 10.8 3.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3378) Ribosomal_60s PF00428.14 ETO16730.1 - 0.19 12.1 22.7 1.8 9.0 5.9 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Hid1 PF12722.2 ETO16730.1 - 4.6 4.7 15.2 6.3 4.3 10.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein WD40 PF00400.27 ETO16731.1 - 6.9e-27 92.3 0.4 3.1e-09 36.3 0.0 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO16731.1 - 0.017 13.2 0.5 0.75 7.8 0.0 2.5 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Ammonium_transp PF00909.16 ETO16732.1 - 5.3e-32 110.7 1.2 6.4e-32 110.5 0.8 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Ank_4 PF13637.1 ETO16732.1 - 0.00047 20.5 0.3 0.0015 18.9 0.1 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO16732.1 - 0.00062 20.0 0.2 0.0019 18.5 0.2 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Yip1 PF04893.12 ETO16732.1 - 0.051 13.0 7.1 0.12 11.9 4.9 1.5 1 0 0 1 1 1 0 Yip1 domain ART PF01129.13 ETO16733.1 - 0.0016 17.5 0.1 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase SH3_1 PF00018.23 ETO16734.1 - 2.2e-13 49.3 0.1 3.8e-13 48.5 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 ETO16734.1 - 3.9e-13 48.7 0.2 6.5e-13 48.0 0.2 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 ETO16734.1 - 4.7e-08 32.4 0.0 7.1e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 ETO16734.1 - 0.00014 21.9 0.4 0.00021 21.4 0.3 1.3 1 0 0 1 1 1 1 Bacterial SH3 domain hSH3 PF14603.1 ETO16734.1 - 0.032 14.2 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Helically-extended SH3 domain DUF2201_N PF13203.1 ETO16734.1 - 0.078 12.1 1.8 0.087 11.9 1.3 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain U3_snoRNA_assoc PF08297.6 ETO16734.1 - 0.12 12.6 6.4 0.15 12.2 4.5 1.2 1 0 0 1 1 1 0 U3 snoRNA associated Paf1 PF03985.8 ETO16734.1 - 0.8 8.3 8.6 0.98 8.0 6.0 1.0 1 0 0 1 1 1 0 Paf1 DUF3042 PF11240.3 ETO16734.1 - 1.3 8.9 4.9 3 7.7 3.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) YqfQ PF14181.1 ETO16734.1 - 1.4 8.9 7.0 1.7 8.6 4.9 1.2 1 0 0 1 1 1 0 YqfQ-like protein Tom22 PF04281.8 ETO16734.1 - 2.1 7.9 6.2 3 7.3 4.3 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 HSP90 PF00183.13 ETO16734.1 - 3.5 5.9 14.2 4.5 5.5 9.9 1.1 1 0 0 1 1 1 0 Hsp90 protein CDC45 PF02724.9 ETO16734.1 - 3.8 5.4 7.0 4.6 5.1 4.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Draxin PF15550.1 ETO16735.1 - 5.1 6.6 11.1 6.5 6.3 7.7 1.2 1 0 0 1 1 1 0 Draxin Borrelia_lipo_2 PF06238.6 ETO16736.1 - 0.059 13.4 0.8 0.073 13.1 0.6 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi BBR25 lipoprotein Ig_2 PF13895.1 ETO16736.1 - 0.095 12.8 0.2 1.2 9.2 0.1 2.1 1 1 0 1 1 1 0 Immunoglobulin domain Ion_trans PF00520.26 ETO16738.1 - 7.8e-13 48.1 0.0 1.3e-12 47.3 0.0 1.4 1 1 0 1 1 1 1 Ion transport protein DUF4424 PF14415.1 ETO16738.1 - 0.014 14.9 0.2 0.015 14.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4424) PKD_channel PF08016.7 ETO16738.1 - 0.1 10.9 0.1 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 Polycystin cation channel WD40 PF00400.27 ETO16739.1 - 1.9e-33 113.1 17.1 7.9e-12 44.5 0.3 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO16739.1 - 3.3e-07 28.8 4.5 0.0015 16.7 0.3 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO16739.1 - 0.016 14.5 4.2 0.1 11.9 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4221) WD40 PF00400.27 ETO16740.1 - 4.7e-41 137.2 13.2 2.8e-13 49.1 0.0 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO16740.1 - 3.1e-08 32.2 0.7 0.014 13.5 0.9 3.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Ig_2 PF13895.1 ETO16740.1 - 0.0035 17.4 1.0 0.015 15.4 0.7 1.9 1 1 0 1 1 1 1 Immunoglobulin domain DUF1900 PF08954.6 ETO16740.1 - 0.085 12.3 0.0 2.1 7.8 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF1900) PH PF00169.24 ETO16741.1 - 7.1e-08 32.5 0.6 1.9e-07 31.1 0.4 1.7 1 0 0 1 1 1 1 PH domain PH_3 PF14593.1 ETO16741.1 - 0.0099 15.7 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 ETO16741.1 - 0.032 14.2 0.2 0.066 13.2 0.2 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain HemX PF04375.9 ETO16742.1 - 0.077 11.5 2.4 1.5 7.2 0.2 2.0 2 0 0 2 2 2 0 HemX AF-4 PF05110.8 ETO16742.1 - 0.34 8.7 13.3 0.39 8.5 9.2 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DNA_pol_viral_N PF00242.12 ETO16742.1 - 1.8 7.5 8.2 2.1 7.2 5.7 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Herpes_capsid PF06112.6 ETO16742.1 - 1.9 8.5 21.8 0.78 9.7 13.2 1.7 1 1 1 2 2 2 0 Gammaherpesvirus capsid protein RAP1 PF07218.6 ETO16742.1 - 3.5 5.6 14.3 4.5 5.2 9.9 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) His_Phos_2 PF00328.17 ETO16743.1 - 1.4e-05 24.5 0.0 2.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Pkinase PF00069.20 ETO16745.1 - 1.6e-22 79.9 0.8 6.1e-20 71.4 0.6 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO16745.1 - 5.7e-06 25.6 0.1 1.8e-05 23.9 0.1 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_98C PF08307.6 ETO16745.1 - 0.00048 19.4 1.5 0.00084 18.6 1.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 98 C-terminal domain APH PF01636.18 ETO16745.1 - 0.00053 19.8 0.1 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family PSCyt3 PF07627.6 ETO16747.1 - 0.45 10.4 4.9 0.26 11.1 1.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1588) RCR PF12273.3 ETO16747.1 - 1.8 9.1 12.2 2 8.9 8.1 1.3 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red SprA-related PF12118.3 ETO16747.1 - 3.6 6.8 13.4 4.4 6.5 9.3 1.0 1 0 0 1 1 1 0 SprA-related family MRP-S25 PF13741.1 ETO16747.1 - 7.3 5.9 14.6 0.61 9.5 5.6 1.9 1 1 1 2 2 2 0 Mitochondrial ribosomal protein S25 WD40 PF00400.27 ETO16748.1 - 3.7e-169 543.3 50.8 8.9e-13 47.5 0.0 16.3 16 0 0 16 16 16 16 WD domain, G-beta repeat DUF1258 PF06869.7 ETO16748.1 - 2.1e-07 30.3 5.2 0.43 9.6 0.0 6.6 4 2 5 9 9 9 3 Protein of unknown function (DUF1258) DPPIV_N PF00930.16 ETO16748.1 - 5.5e-07 28.4 0.4 0.74 8.3 0.0 5.9 3 3 5 8 8 8 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region Pentapeptide_4 PF13599.1 ETO16748.1 - 5.1e-06 26.1 0.2 1.4e-05 24.7 0.1 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Mid2 PF04478.7 ETO16748.1 - 6.6e-05 22.3 17.5 0.3 10.4 0.2 8.4 4 3 6 10 10 10 2 Mid2 like cell wall stress sensor Pentapeptide PF00805.17 ETO16748.1 - 0.00026 20.1 0.4 0.00079 18.6 0.3 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) NYD-SP28_assoc PF14775.1 ETO16748.1 - 0.00084 18.9 13.6 88 2.9 0.0 10.7 14 0 0 14 14 14 0 Sperm tail C-terminal domain PD40 PF07676.7 ETO16748.1 - 0.001 18.6 12.6 4 7.2 0.1 7.6 8 0 0 8 8 8 1 WD40-like Beta Propeller Repeat Pentapeptide_3 PF13576.1 ETO16748.1 - 0.001 18.8 0.7 0.0043 16.8 0.5 2.1 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) DUF1938 PF09153.5 ETO16748.1 - 0.0033 17.1 1.9 0.85 9.4 0.0 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF1938) La PF05383.12 ETO16749.1 - 5.6e-05 22.8 0.0 0.00019 21.1 0.0 1.9 1 0 0 1 1 1 1 La domain DUF3574 PF12098.3 ETO16749.1 - 0.21 11.1 2.1 0.59 9.7 1.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) Jnk-SapK_ap_N PF09744.4 ETO16749.1 - 0.24 11.3 20.8 0.22 11.5 13.5 1.6 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 HrcA PF01628.16 ETO16749.1 - 0.27 10.7 5.6 0.41 10.1 3.9 1.3 1 0 0 1 1 1 0 HrcA protein C terminal domain ATG16 PF08614.6 ETO16750.1 - 0.011 15.6 8.7 0.011 15.6 6.0 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) IncA PF04156.9 ETO16750.1 - 0.014 15.0 9.3 0.03 13.9 6.5 1.5 1 0 0 1 1 1 0 IncA protein PEARLI-4 PF05278.7 ETO16750.1 - 0.021 14.1 4.4 0.038 13.3 3.0 1.4 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) AHS1 PF02682.11 ETO16750.1 - 0.16 11.4 0.5 0.28 10.6 0.4 1.4 1 0 0 1 1 1 0 Allophanate hydrolase subunit 1 SlyX PF04102.7 ETO16750.1 - 3.9 7.9 7.8 2.8 8.3 3.5 2.2 1 1 1 2 2 2 0 SlyX ShlB PF03865.8 ETO16752.1 - 0.063 12.0 0.4 0.088 11.5 0.3 1.2 1 0 0 1 1 1 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB ELMO_CED12 PF04727.8 ETO16752.1 - 0.85 9.1 5.6 0.47 9.9 2.4 1.6 1 1 1 2 2 2 0 ELMO/CED-12 family DUF2663 PF10864.3 ETO16752.1 - 1.5 9.0 10.2 0.038 14.2 1.5 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2663) Hrs_helical PF12210.3 ETO16753.1 - 0.052 13.7 4.6 1 9.6 0.1 3.2 1 1 2 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Prok-TraM PF09228.5 ETO16757.1 - 0.067 13.3 1.8 0.096 12.8 0.4 1.9 1 1 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM RMMBL PF07521.7 ETO16758.1 - 0.00025 20.7 0.0 0.00048 19.8 0.0 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Herpes_capsid PF06112.6 ETO16758.1 - 0.027 14.5 11.4 0.051 13.6 5.1 2.6 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Voltage_CLC PF00654.15 ETO16759.1 - 5e-12 45.5 8.8 4.2e-11 42.4 0.3 3.0 2 1 1 3 3 3 2 Voltage gated chloride channel ABC2_membrane_4 PF12730.2 ETO16759.1 - 0.0058 15.8 4.1 0.0058 15.8 2.9 1.9 2 0 0 2 2 2 1 ABC-2 family transporter protein FAM176 PF14851.1 ETO16759.1 - 0.025 14.2 0.6 0.046 13.3 0.4 1.4 1 0 0 1 1 1 0 FAM176 family EI24 PF07264.6 ETO16759.1 - 0.37 10.1 7.5 0.071 12.5 2.5 1.8 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) DUF4131 PF13567.1 ETO16759.1 - 1.7 8.0 7.8 4 6.8 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Voltage_CLC PF00654.15 ETO16760.1 - 1.7e-22 79.9 1.6 2.2e-22 79.6 1.1 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel TauE PF01925.14 ETO16760.1 - 0.021 14.2 5.3 0.36 10.2 1.3 2.2 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE DUF912 PF06024.7 ETO16760.1 - 0.022 14.8 3.3 0.47 10.5 0.0 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Yip1 PF04893.12 ETO16760.1 - 1.4 8.3 8.9 0.32 10.4 1.7 2.2 2 0 0 2 2 2 0 Yip1 domain DUF3169 PF11368.3 ETO16760.1 - 3.4 6.8 7.1 0.7 9.0 0.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) MA3 PF02847.12 ETO16761.1 - 0.0048 16.5 0.6 0.024 14.3 0.1 2.3 2 0 0 2 2 2 1 MA3 domain Occludin_ELL PF07303.8 ETO16761.1 - 2.4 8.9 7.2 11 6.8 4.1 2.4 2 1 0 2 2 2 0 Occludin homology domain PHP PF02811.14 ETO16762.1 - 0.032 14.0 0.0 0.038 13.7 0.0 1.1 1 0 0 1 1 1 0 PHP domain Ribosomal_60s PF00428.14 ETO16762.1 - 0.66 10.4 10.2 1.1 9.7 5.8 2.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein STAS PF01740.16 ETO16763.1 - 8.6e-20 70.3 0.1 1.4e-19 69.6 0.1 1.4 1 0 0 1 1 1 1 STAS domain Sulfate_transp PF00916.15 ETO16763.1 - 3.9e-07 29.3 1.9 9.3e-07 28.1 1.3 1.6 1 0 0 1 1 1 1 Sulfate transporter family Methyltransf_3 PF01596.12 ETO16764.1 - 5.9e-61 205.0 0.2 7.2e-61 204.8 0.1 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 ETO16764.1 - 1.5e-14 54.6 0.0 2.4e-13 50.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO16764.1 - 6.8e-08 33.0 0.0 1.4e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO16764.1 - 1.4e-06 28.0 0.2 2e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 ETO16764.1 - 0.00082 18.5 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 ETO16764.1 - 0.011 16.2 0.0 0.026 15.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 ETO16764.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 ETO16764.1 - 0.028 13.5 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family GCD14 PF08704.5 ETO16764.1 - 0.08 12.4 0.0 0.14 11.6 0.0 1.4 1 1 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Mcp5_PH PF12814.2 ETO16767.1 - 0.0027 17.6 0.1 0.0046 16.8 0.1 1.4 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology EppA_BapA PF07268.6 ETO16767.1 - 0.023 14.3 0.1 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Exported protein precursor (EppA/BapA) PH PF00169.24 ETO16767.1 - 0.11 12.7 1.8 0.34 11.1 1.2 1.8 1 1 0 1 1 1 0 PH domain WD40 PF00400.27 ETO16768.1 - 2.4e-37 125.4 14.6 7.3e-12 44.6 0.4 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO16768.1 - 7.5e-08 30.9 5.4 0.031 12.4 0.2 4.3 2 2 2 4 4 4 4 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO16768.1 - 8.5e-07 29.2 1.0 8.5e-07 29.2 0.7 3.0 3 1 1 4 4 4 1 TRAF-type zinc finger Arm PF00514.18 ETO16769.1 - 0.017 14.9 0.6 4.2 7.3 0.1 2.6 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Arm PF00514.18 ETO16770.1 - 1.2e-13 50.2 0.3 0.003 17.3 0.0 4.7 5 0 0 5 5 5 4 Armadillo/beta-catenin-like repeat RICTOR_V PF14668.1 ETO16770.1 - 0.043 13.7 0.0 15 5.6 0.0 3.6 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_EZ PF13513.1 ETO16770.1 - 0.054 13.9 0.0 8 7.0 0.0 3.1 2 1 1 3 3 3 0 HEAT-like repeat HEAT_2 PF13646.1 ETO16770.1 - 0.057 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 HEAT repeats Ninjurin PF04923.7 ETO16772.1 - 2 8.1 11.1 0.23 11.1 3.4 2.2 2 0 0 2 2 2 0 Ninjurin HEAT_2 PF13646.1 ETO16773.1 - 3.4e-06 27.2 0.3 0.00078 19.6 0.0 2.7 1 1 2 3 3 3 2 HEAT repeats HEAT PF02985.17 ETO16773.1 - 0.0044 16.9 0.0 1.2 9.3 0.0 3.0 3 0 0 3 3 3 1 HEAT repeat Fe_hyd_lg_C PF02906.9 ETO16773.1 - 0.015 14.5 0.2 0.025 13.8 0.1 1.2 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Pept_tRNA_hydro PF01195.14 ETO16773.1 - 0.028 13.9 0.1 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase HEAT_EZ PF13513.1 ETO16773.1 - 0.031 14.7 0.2 0.77 10.3 0.0 2.8 2 1 0 2 2 2 0 HEAT-like repeat LRR_6 PF13516.1 ETO16773.1 - 0.2 11.7 1.3 31 5.0 0.0 2.9 1 1 1 2 2 2 0 Leucine Rich repeat Ank_4 PF13637.1 ETO16774.1 - 0.11 12.9 0.1 3.7 8.1 0.0 2.9 3 1 0 3 3 3 0 Ankyrin repeats (many copies) HATPase_c PF02518.21 ETO16775.1 - 8.4e-11 41.5 0.0 1.1e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 ETO16775.1 - 1.6e-05 24.6 0.0 2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF641 PF04859.7 ETO16776.1 - 0.027 14.2 2.4 0.052 13.3 1.7 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF4094 PF13334.1 ETO16776.1 - 0.057 13.8 1.8 0.12 12.8 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) IncA PF04156.9 ETO16776.1 - 0.059 12.9 1.8 0.096 12.2 1.2 1.3 1 0 0 1 1 1 0 IncA protein SPT16 PF08644.6 ETO16776.1 - 0.087 12.6 5.1 0.18 11.6 3.6 1.5 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) DUF3734 PF12536.3 ETO16776.1 - 0.12 12.4 0.1 2.5 8.2 0.3 2.2 2 0 0 2 2 2 0 Patatin phospholipase FANCL_C PF11793.3 ETO16776.1 - 0.62 10.0 4.5 0.24 11.3 0.4 2.3 2 1 0 2 2 2 0 FANCL C-terminal domain Med4 PF10018.4 ETO16776.1 - 0.82 9.0 5.1 1.3 8.3 3.5 1.3 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 WD40 PF00400.27 ETO16777.1 - 7e-60 196.9 20.4 6e-11 41.7 0.1 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO16777.1 - 8.1e-12 44.0 6.8 0.00021 19.5 0.1 5.1 2 1 2 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO16777.1 - 0.031 13.0 13.1 7.1 5.2 4.4 4.3 1 1 2 3 3 3 0 Nup133 N terminal like CAP_GLY PF01302.20 ETO16778.1 - 2.4e-08 33.5 1.3 0.00064 19.3 0.3 2.2 1 1 1 2 2 2 2 CAP-Gly domain PBP5_C PF07943.8 ETO16779.1 - 0.031 14.3 0.2 0.08 12.9 0.0 1.7 2 0 0 2 2 2 0 Penicillin-binding protein 5, C-terminal domain RGS PF00615.14 ETO16781.1 - 1.8e-05 24.8 4.6 2.1e-05 24.5 0.0 2.9 2 1 1 3 3 3 1 Regulator of G protein signaling domain DUF1843 PF08898.5 ETO16782.1 - 6 6.9 9.8 3.4 7.7 0.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) ESAG1 PF03238.8 ETO16784.1 - 0.037 13.3 0.1 0.056 12.7 0.1 1.2 1 0 0 1 1 1 0 ESAG protein KH_1 PF00013.24 ETO16786.1 - 0.00077 19.0 0.0 0.015 14.9 0.0 2.3 2 0 0 2 2 2 1 KH domain PAD_M PF08527.5 ETO16786.1 - 0.0012 18.2 1.5 0.089 12.1 0.3 2.6 2 0 0 2 2 2 2 Protein-arginine deiminase (PAD) middle domain KH_3 PF13014.1 ETO16786.1 - 0.045 13.4 0.0 0.54 9.9 0.0 2.7 3 0 0 3 3 3 0 KH domain DUF2203 PF09969.4 ETO16788.1 - 0.37 11.0 3.5 0.27 11.4 0.3 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Peptidase_C37 PF05416.7 ETO16788.1 - 1.3 7.1 4.6 1.4 7.1 3.2 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase DUF2201_N PF13203.1 ETO16788.1 - 1.4 8.0 5.2 1.7 7.7 3.6 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain RR_TM4-6 PF06459.7 ETO16788.1 - 2 8.2 9.1 3.3 7.5 6.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 ETO16788.1 - 4.1 6.6 17.7 5.6 6.2 12.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Serpin PF00079.15 ETO16790.1 - 0.11 11.6 2.1 0.11 11.5 1.5 1.0 1 0 0 1 1 1 0 Serpin (serine protease inhibitor) DUF1863 PF08937.6 ETO16790.1 - 0.13 12.3 1.5 0.12 12.3 1.1 1.0 1 0 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) PRP1_N PF06424.7 ETO16790.1 - 0.71 10.1 6.5 0.73 10.1 4.5 1.0 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal PBP1_TM PF14812.1 ETO16790.1 - 1.2 9.5 4.4 1.3 9.4 3.1 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Chorein_N PF12624.2 ETO16792.1 - 1e-24 86.3 1.1 4.1e-24 84.3 0.0 2.2 2 1 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Toxin_64 PF15542.1 ETO16792.1 - 0.32 11.6 4.3 0.64 10.6 3.0 1.5 1 1 0 1 1 1 0 Putative toxin 64 TFIIA PF03153.8 ETO16793.1 - 0.53 10.1 28.9 0.75 9.6 20.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit YjgP_YjgQ PF03739.9 ETO16793.1 - 0.75 8.4 6.9 1.5 7.4 0.0 2.4 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family HAP1_N PF04849.8 ETO16794.1 - 0.014 14.3 5.4 0.016 14.1 3.8 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF4062 PF13271.1 ETO16794.1 - 0.036 14.0 0.1 0.066 13.2 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4062) DUF106 PF01956.11 ETO16794.1 - 0.043 13.3 5.6 0.057 12.9 3.9 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 Pox_Ag35 PF03286.9 ETO16794.1 - 0.066 12.7 4.2 0.084 12.3 2.9 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PTH2 PF01981.11 ETO16794.1 - 0.072 12.7 1.8 0.11 12.2 1.2 1.4 1 1 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 Sec62 PF03839.11 ETO16794.1 - 0.076 12.4 7.3 0.09 12.1 5.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 ATP-synt_F PF01990.12 ETO16794.1 - 0.1 12.9 1.8 0.15 12.4 1.2 1.4 1 1 0 1 1 1 0 ATP synthase (F/14-kDa) subunit SIR2 PF02146.12 ETO16794.1 - 1.6 8.3 6.8 1.7 8.3 4.2 1.4 1 1 0 1 1 1 0 Sir2 family Chordopox_G3 PF06129.7 ETO16795.1 - 0.7 10.0 7.3 10 6.2 0.1 2.6 1 1 1 2 2 2 0 Chordopoxvirus G3 protein Herpes_US9 PF06072.6 ETO16796.1 - 0.26 11.1 0.2 0.26 11.1 0.1 2.2 1 1 1 2 2 2 0 Alphaherpesvirus tegument protein US9 DUF3899 PF13038.1 ETO16796.1 - 2.3 8.4 9.5 0.055 13.6 2.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) DUF4181 PF13789.1 ETO16796.1 - 4.8 7.1 6.9 10 6.0 4.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4181) Peptidase_S49_N PF08496.5 ETO16796.1 - 9 6.0 8.3 13 5.5 5.8 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SHP PF03579.8 ETO16797.1 - 5.4 6.4 11.1 0.19 11.1 3.1 2.0 2 0 0 2 2 2 0 Small hydrophobic protein PDEase_I PF00233.14 ETO16799.1 - 5.8e-14 52.4 0.2 2.3e-12 47.2 0.0 2.6 2 1 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Imm20 PF15568.1 ETO16800.1 - 0.0085 15.9 0.4 1.2 8.9 0.0 2.1 2 0 0 2 2 2 2 Immunity protein 20 NPR3 PF03666.8 ETO16800.1 - 0.15 10.6 4.9 0.15 10.5 3.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Neur_chan_memb PF02932.11 ETO16800.1 - 0.21 11.4 1.2 0.26 11.1 0.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Sec62 PF03839.11 ETO16800.1 - 0.59 9.5 9.9 0.76 9.1 6.8 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Vfa1 PF08432.5 ETO16800.1 - 1.2 9.1 13.6 1.5 8.8 9.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PPV_E2_N PF00508.12 ETO16801.1 - 0.024 13.8 0.0 0.036 13.2 0.0 1.2 1 0 0 1 1 1 0 E2 (early) protein, N terminal SNF2_N PF00176.18 ETO16802.1 - 7.8e-57 192.3 0.0 1.2e-56 191.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETO16802.1 - 2.2e-14 53.0 0.0 7.3e-14 51.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF912 PF06024.7 ETO16802.1 - 4.7e-05 23.3 0.1 4.7e-05 23.3 0.1 3.7 3 0 0 3 3 3 1 Nucleopolyhedrovirus protein of unknown function (DUF912) 7tm_1 PF00001.16 ETO16802.1 - 0.0057 15.8 0.2 0.021 13.9 0.0 2.0 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) CDC45 PF02724.9 ETO16802.1 - 0.0066 14.5 0.3 0.0066 14.5 0.2 2.3 2 0 0 2 2 2 1 CDC45-like protein Ni_hydr_CYTB PF01292.15 ETO16802.1 - 0.0066 15.8 0.0 0.031 13.6 0.0 1.9 2 0 0 2 2 2 1 Prokaryotic cytochrome b561 ABC2_membrane_3 PF12698.2 ETO16802.1 - 0.015 14.3 0.0 0.086 11.8 0.0 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF4448 PF14610.1 ETO16802.1 - 0.031 13.7 0.0 0.031 13.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) ABC_membrane PF00664.18 ETO16802.1 - 0.1 11.9 5.5 1.5 8.1 0.1 2.6 3 0 0 3 3 3 0 ABC transporter transmembrane region RR_TM4-6 PF06459.7 ETO16802.1 - 2 8.2 18.9 2.6 7.8 4.3 2.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 dNK PF01712.14 ETO16803.1 - 3.7e-05 23.6 1.5 6.5e-05 22.8 0.1 1.9 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_28 PF13521.1 ETO16804.1 - 3.9e-05 23.6 0.0 4.5e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO16804.1 - 0.031 15.1 0.1 0.042 14.6 0.1 1.1 1 0 0 1 1 1 0 AAA domain Thioredoxin PF00085.15 ETO16805.1 - 9.5e-05 22.0 0.1 0.00024 20.7 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin Pkinase PF00069.20 ETO16806.1 - 2.2e-16 59.7 0.0 2.8e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO16806.1 - 0.0054 15.8 0.0 0.0068 15.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase DUF1363 PF07101.6 ETO16807.1 - 0.028 14.5 0.1 0.84 9.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1363) DUF572 PF04502.8 ETO16807.1 - 0.37 9.9 15.2 0.67 9.1 10.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) LRR_4 PF12799.2 ETO16807.1 - 1.8 8.3 9.4 0.59 9.8 0.1 3.6 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO16807.1 - 2.5 7.9 5.8 1.9 8.2 0.1 2.9 3 0 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.1 ETO16807.1 - 3.7 7.8 5.2 52 4.3 0.2 3.7 3 0 0 3 3 3 0 Leucine Rich repeat GAGA_bind PF06217.7 ETO16807.1 - 3.9 7.3 10.5 9.5 6.0 7.3 1.6 1 0 0 1 1 1 0 GAGA binding protein-like family zf-CCHC_2 PF13696.1 ETO16808.1 - 6.8e-07 28.6 9.9 7.7e-06 25.3 4.6 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC PF00098.18 ETO16808.1 - 0.002 17.9 7.1 0.002 17.9 4.9 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.1 ETO16808.1 - 0.06 13.0 5.7 0.069 12.8 1.0 2.5 2 0 0 2 2 2 0 Zinc knuckle EMP70 PF02990.11 ETO16809.1 - 1.7e-13 49.9 7.4 2.8e-13 49.1 5.2 1.7 1 1 0 1 1 1 1 Endomembrane protein 70 DSPc PF00782.15 ETO16810.1 - 2.7e-06 27.0 0.0 1.4e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain SR-25 PF10500.4 ETO16812.1 - 0.001 18.5 9.9 0.0012 18.3 6.9 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Dsh_C PF12316.3 ETO16812.1 - 0.33 11.0 8.2 0.56 10.2 5.7 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Period_C PF12114.3 ETO16812.1 - 1.4 8.4 9.2 2 7.9 6.4 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region CDC45 PF02724.9 ETO16812.1 - 1.7 6.6 10.2 1.7 6.5 7.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Glypican PF01153.14 ETO16812.1 - 3.5 6.1 7.2 4.5 5.7 5.0 1.1 1 0 0 1 1 1 0 Glypican DUF1694 PF07997.6 ETO16814.1 - 0.045 13.6 1.4 2.5 8.0 0.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1694) Integrase_1 PF12835.2 ETO16814.1 - 0.068 12.9 0.1 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Integrase DUF1664 PF07889.7 ETO16814.1 - 2.6 7.8 7.1 1.2 8.9 1.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF903 PF06004.7 ETO16816.1 - 0.067 12.7 3.0 9.3 5.8 0.0 3.7 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF903) DUF1496 PF07383.7 ETO16816.1 - 0.11 11.8 1.1 15 4.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1496) G-alpha PF00503.15 ETO16817.1 - 4.6e-23 81.5 2.6 5.4e-23 81.3 1.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit NodS PF05401.6 ETO16817.1 - 0.076 12.4 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) EF-hand_7 PF13499.1 ETO16818.1 - 3.1e-13 49.6 0.9 3.9e-10 39.7 0.3 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 ETO16818.1 - 2.6e-10 39.7 3.0 2.3e-08 33.5 0.8 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO16818.1 - 5.2e-10 38.3 3.4 0.0068 16.2 0.1 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.27 ETO16818.1 - 8e-10 37.3 5.8 2.1e-06 26.6 0.5 3.4 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 ETO16818.1 - 2.9e-06 26.3 6.5 0.001 18.2 1.5 3.6 3 0 0 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.4 ETO16818.1 - 0.013 15.4 1.5 0.046 13.7 0.5 1.9 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 ETO16818.1 - 0.019 14.7 2.2 0.027 14.1 0.6 1.9 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand 23S_rRNA_IVP PF05635.6 ETO16818.1 - 0.052 13.4 0.2 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 23S rRNA-intervening sequence protein GPS PF01825.16 ETO16819.1 - 1.9e-08 34.2 3.8 1.9e-08 34.2 2.6 1.9 2 0 0 2 2 2 1 Latrophilin/CL-1-like GPS domain SlyX PF04102.7 ETO16820.1 - 0.0014 18.9 2.0 0.0028 17.9 0.5 2.1 2 0 0 2 2 2 1 SlyX Spectrin PF00435.16 ETO16820.1 - 0.15 12.3 5.7 0.32 11.2 3.9 1.8 1 1 0 1 1 1 0 Spectrin repeat Fzo_mitofusin PF04799.8 ETO16820.1 - 0.34 10.2 3.0 0.7 9.2 2.0 1.5 1 0 0 1 1 1 0 fzo-like conserved region Prefoldin_2 PF01920.15 ETO16820.1 - 0.83 9.4 12.3 0.11 12.2 2.9 2.7 3 0 0 3 3 3 0 Prefoldin subunit DivIC PF04977.10 ETO16820.1 - 1.5 8.3 14.4 1.7 8.1 2.8 3.3 3 0 0 3 3 3 0 Septum formation initiator V_ATPase_I PF01496.14 ETO16820.1 - 2.7 5.7 7.1 3.3 5.4 4.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cypo_polyhedrin PF05865.6 ETO16821.1 - 0.034 13.3 0.1 0.063 12.4 0.0 1.4 1 0 0 1 1 1 0 Cypovirus polyhedrin protein CTNNB1_binding PF08347.6 ETO16822.1 - 0.068 13.4 1.0 0.098 12.9 0.7 1.3 1 0 0 1 1 1 0 N-terminal CTNNB1 binding Pap_E4 PF02711.9 ETO16823.1 - 0.3 11.9 5.8 0.073 13.8 1.8 1.7 2 0 0 2 2 2 0 E4 protein ABC_membrane PF00664.18 ETO16824.1 - 4.6e-30 104.9 10.4 9.9e-18 64.5 1.2 2.4 2 1 1 3 3 3 2 ABC transporter transmembrane region DUF3306 PF11748.3 ETO16825.1 - 0.59 10.7 5.4 0.72 10.5 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Radial_spoke PF04712.7 ETO16825.1 - 1.5 7.4 9.3 1.3 7.6 6.4 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Pox_Ag35 PF03286.9 ETO16825.1 - 1.9 7.9 7.3 1.9 7.9 5.1 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein VID27 PF08553.5 ETO16825.1 - 2.3 6.3 12.6 2.4 6.2 8.7 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Nop14 PF04147.7 ETO16825.1 - 4 5.2 15.5 3.7 5.3 10.7 1.0 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 ETO16825.1 - 5.9 5.2 16.2 5.6 5.3 11.2 1.0 1 0 0 1 1 1 0 Daxx Family Prothymosin PF03247.9 ETO16825.1 - 5.9 7.0 26.7 7.2 6.8 18.5 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family BUD22 PF09073.5 ETO16825.1 - 7.7 5.4 11.9 7.7 5.4 8.3 1.0 1 0 0 1 1 1 0 BUD22 DUF4637 PF15470.1 ETO16825.1 - 8.4 5.9 7.5 8 6.0 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) TRAP_alpha PF03896.11 ETO16825.1 - 9.7 5.0 11.9 9.4 5.1 8.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit HD-ZIP_N PF04618.7 ETO16826.1 - 0.11 12.9 4.0 0.066 13.7 1.1 1.8 2 0 0 2 2 2 0 HD-ZIP protein N terminus Spore_coat_CotO PF14153.1 ETO16827.1 - 8.1 5.8 34.1 0.2 11.0 2.6 2.2 2 0 0 2 2 2 0 Spore coat protein CotO Plasmodium_Vir PF05795.6 ETO16828.1 - 0.0021 17.3 1.0 0.0043 16.3 0.0 1.8 2 0 0 2 2 2 1 Plasmodium vivax Vir protein Peroxin-3 PF04882.7 ETO16828.1 - 0.0097 14.6 0.0 0.013 14.2 0.0 1.1 1 0 0 1 1 1 1 Peroxin-3 DUF4064 PF13273.1 ETO16828.1 - 0.011 15.8 6.6 0.21 11.6 4.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF4181 PF13789.1 ETO16828.1 - 0.23 11.3 11.0 0.16 11.8 5.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) Secretin_N_2 PF07655.8 ETO16828.1 - 1.6 9.1 10.0 2.7 8.4 6.9 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Vfa1 PF08432.5 ETO16829.1 - 0.17 11.9 11.7 0.21 11.6 8.1 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 ETO16829.1 - 0.19 9.6 6.5 0.21 9.5 4.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Merozoite_SPAM PF07133.6 ETO16829.1 - 0.94 9.3 21.3 1.3 8.9 14.8 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SspB PF04386.8 ETO16829.1 - 1.2 8.7 7.9 1.7 8.2 5.4 1.2 1 0 0 1 1 1 0 Stringent starvation protein B YqfQ PF14181.1 ETO16829.1 - 2.6 8.0 11.0 3.5 7.6 7.6 1.3 1 0 0 1 1 1 0 YqfQ-like protein TRAP_alpha PF03896.11 ETO16829.1 - 2.9 6.7 6.5 3.6 6.5 4.5 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF1510 PF07423.6 ETO16829.1 - 3.7 6.8 17.8 5 6.4 12.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RNase_H2-Ydr279 PF09468.5 ETO16829.1 - 4 6.5 12.8 5.7 6.0 8.9 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) POX PF07526.6 ETO16829.1 - 5.2 7.2 8.0 4.6 7.4 4.5 1.6 2 0 0 2 2 2 0 Associated with HOX Ribosomal_L28e PF01778.12 ETO16830.1 - 4.5e-10 39.9 6.6 4.5e-10 39.9 4.5 2.3 1 1 1 2 2 2 1 Ribosomal L28e protein family Choline_kinase PF01633.15 ETO16830.1 - 0.063 12.8 0.7 0.1 12.1 0.5 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1446 PF07287.6 ETO16830.1 - 0.14 10.6 0.8 0.17 10.3 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1446) Dala_Dala_lig_N PF01820.16 ETO16831.1 - 0.55 10.5 2.8 0.48 10.7 0.7 1.8 1 1 1 2 2 2 0 D-ala D-ala ligase N-terminus Ribosomal_S4 PF00163.14 ETO16831.1 - 5.2 7.5 6.8 15 6.0 2.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S4/S9 N-terminal domain FHIPEP PF00771.15 ETO16832.1 - 0.64 8.2 3.2 1 7.6 2.2 1.2 1 0 0 1 1 1 0 FHIPEP family DUF21 PF01595.15 ETO16833.1 - 3.1e-21 75.4 3.4 4.6e-20 71.6 2.3 2.2 1 1 0 1 1 1 1 Domain of unknown function DUF21 Na_H_Exchanger PF00999.16 ETO16834.1 - 1.9e-28 99.0 14.3 2.1e-28 98.9 9.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Claudin_2 PF13903.1 ETO16834.1 - 0.23 11.1 8.1 0.29 10.8 5.6 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction PUB PF09409.5 ETO16836.1 - 0.00013 21.6 1.0 0.00074 19.2 0.7 2.3 1 1 0 1 1 1 1 PUB domain Methyltransf_16 PF10294.4 ETO16838.1 - 5.6e-09 35.6 0.5 0.00046 19.6 0.0 2.4 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_23 PF13489.1 ETO16838.1 - 0.00011 21.9 0.0 0.00019 21.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO16838.1 - 0.0014 18.2 0.7 0.77 9.3 0.0 3.0 3 1 1 4 4 4 2 Methyltransferase domain Methyltransf_18 PF12847.2 ETO16838.1 - 0.0019 18.7 0.0 0.0039 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO16838.1 - 0.0039 17.6 0.4 0.1 13.0 0.2 2.8 2 1 0 2 2 2 1 Methyltransferase domain AdoMet_MTase PF07757.8 ETO16838.1 - 0.064 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase MTS PF05175.9 ETO16838.1 - 0.12 11.7 0.0 2.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain DUF2317 PF10079.4 ETO16838.1 - 2.8 6.4 10.4 64 1.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2317) Chorismate_bind PF00425.13 ETO16839.1 - 0.14 11.4 0.3 0.49 9.6 0.0 1.9 2 0 0 2 2 2 0 chorismate binding enzyme NAD_binding_6 PF08030.7 ETO16840.1 - 1.8e-11 44.1 0.0 4.7e-11 42.8 0.0 1.6 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 ETO16840.1 - 0.036 14.6 0.9 0.44 11.1 0.1 2.6 3 1 0 3 3 3 0 Oxidoreductase NAD-binding domain WD40 PF00400.27 ETO16842.1 - 1.3e-73 240.4 18.3 1.4e-11 43.7 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO16842.1 - 1.8e-09 37.5 2.3 0.00089 19.0 0.1 3.7 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO16842.1 - 0.00056 18.1 7.4 1.7 6.7 0.8 5.1 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO16842.1 - 0.0006 18.2 1.2 0.45 8.7 0.0 3.4 3 1 1 4 4 4 2 Cytochrome D1 heme domain PD40 PF07676.7 ETO16842.1 - 0.0012 18.4 0.6 6.1 6.6 0.0 3.6 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Kelch_6 PF13964.1 ETO16842.1 - 0.0018 18.3 2.4 0.39 10.9 0.1 3.7 3 0 0 3 3 3 1 Kelch motif DUF4073 PF13285.1 ETO16842.1 - 0.0029 17.0 0.1 2.4 7.5 0.0 3.4 3 1 0 3 3 3 1 Domain of unknown function (DUF4073) PQQ_2 PF13360.1 ETO16842.1 - 0.02 14.3 0.2 0.068 12.6 0.1 2.0 1 1 0 1 1 1 0 PQQ-like domain Kelch_5 PF13854.1 ETO16842.1 - 0.048 13.6 4.6 2.6 8.1 0.4 3.6 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.10 ETO16842.1 - 1.7 8.5 5.9 3.1 7.7 0.1 4.1 5 0 0 5 5 5 0 Kelch motif WD40 PF00400.27 ETO16843.1 - 2.9e-76 248.8 16.4 1.2e-13 50.3 0.5 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO16843.1 - 3.8e-13 48.4 10.4 0.0089 14.2 0.0 5.8 1 1 4 6 6 6 6 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO16843.1 - 6.5e-12 45.5 1.7 1.7e-05 24.5 0.0 3.6 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO16843.1 - 0.0076 14.5 3.9 0.96 7.6 0.2 3.2 2 2 2 4 4 4 2 Cytochrome D1 heme domain Resistin PF06954.6 ETO16843.1 - 0.011 15.9 1.8 10 6.4 0.0 4.3 3 2 3 6 6 6 0 Resistin DUF4221 PF13970.1 ETO16843.1 - 0.039 13.2 0.6 0.36 10.1 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4221) PD40 PF07676.7 ETO16843.1 - 1.7 8.4 4.9 46 3.8 0.0 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Kelch_4 PF13418.1 ETO16844.1 - 0.0017 18.1 0.1 1.8 8.3 0.0 2.4 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO16844.1 - 0.0083 16.2 0.2 3.5 7.9 0.0 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.10 ETO16844.1 - 0.012 15.3 0.3 0.8 9.5 0.1 2.4 1 1 1 2 2 2 0 Kelch motif Kelch_4 PF13418.1 ETO16845.1 - 1.6e-06 27.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO16845.1 - 0.00046 19.8 0.6 0.2 11.4 0.1 2.7 2 1 0 2 2 2 2 Kelch motif Kelch_6 PF13964.1 ETO16845.1 - 0.0072 16.4 0.1 0.77 10.0 0.1 2.4 2 0 0 2 2 2 1 Kelch motif DUF4408 PF14364.1 ETO16845.1 - 0.11 12.0 0.1 0.19 11.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4408) Kelch_1 PF01344.20 ETO16845.1 - 0.94 9.0 3.6 17 5.0 0.0 2.9 2 1 0 2 2 2 0 Kelch motif PBP_sp32 PF07222.7 ETO16846.1 - 0.057 12.5 0.1 0.065 12.3 0.1 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Prp19 PF08606.6 ETO16847.1 - 0.077 12.7 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 Prp19/Pso4-like Vfa1 PF08432.5 ETO16847.1 - 0.34 10.9 7.4 0.44 10.5 5.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Mito_carr PF00153.22 ETO16848.1 - 5.7e-19 67.6 1.2 2.1e-08 33.7 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein AMP-binding PF00501.23 ETO16849.1 - 4.6e-30 104.3 0.0 5e-30 104.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme MoCo_carrier PF12694.2 ETO16850.1 - 0.11 11.9 0.0 0.31 10.4 0.0 1.7 1 1 1 2 2 2 0 Putative molybdenum carrier Cation_efflux PF01545.16 ETO16851.1 - 5.5e-06 25.6 0.7 6e-06 25.5 0.1 1.4 1 1 0 1 1 1 1 Cation efflux family DUF607 PF04678.8 ETO16852.1 - 0.036 13.9 1.5 0.069 13.0 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF607 Sulfatase_C PF14707.1 ETO16852.1 - 0.044 14.0 0.1 0.074 13.3 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase CENP-Q PF13094.1 ETO16852.1 - 0.46 10.4 7.2 1.1 9.2 5.0 1.6 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit POX PF07526.6 ETO16853.1 - 9.4 6.4 7.0 43 4.3 4.8 1.9 1 1 0 1 1 1 0 Associated with HOX zf-DHHC PF01529.15 ETO16854.1 - 1.7e-34 118.7 12.4 2.7e-34 118.0 8.6 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase PepSY_TM_2 PF13703.1 ETO16854.1 - 0.018 15.1 0.1 0.018 15.1 0.1 1.9 2 0 0 2 2 2 0 PepSY-associated TM helix Ada_Zn_binding PF02805.11 ETO16854.1 - 8 6.1 10.8 6.7 6.3 2.6 2.5 3 0 0 3 3 3 0 Metal binding domain of Ada GAS PF13851.1 ETO16856.1 - 0.0094 15.1 1.6 0.011 14.9 1.1 1.0 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Laminin_II PF06009.7 ETO16856.1 - 0.011 15.5 2.3 0.012 15.3 1.6 1.1 1 0 0 1 1 1 0 Laminin Domain II DUF3647 PF12363.3 ETO16856.1 - 0.011 15.8 0.4 0.017 15.1 0.2 1.5 1 1 0 1 1 1 0 Phage protein Phage_GP20 PF06810.6 ETO16856.1 - 0.013 14.9 2.3 0.015 14.7 1.6 1.0 1 0 0 1 1 1 0 Phage minor structural protein GP20 DivIVA PF05103.8 ETO16856.1 - 0.039 13.9 1.3 0.052 13.6 0.9 1.1 1 0 0 1 1 1 0 DivIVA protein DUF4559 PF15112.1 ETO16856.1 - 0.041 13.0 3.3 0.047 12.8 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) WXG100 PF06013.7 ETO16856.1 - 0.065 13.2 1.2 3.2 7.8 0.2 2.1 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DUF4172 PF13776.1 ETO16856.1 - 0.071 13.2 0.1 0.092 12.8 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4172) GUN4 PF05419.7 ETO16856.1 - 0.078 12.8 0.2 0.088 12.6 0.1 1.2 1 1 0 1 1 1 0 GUN4-like Tektin PF03148.9 ETO16856.1 - 0.1 11.1 3.8 0.13 10.7 2.6 1.0 1 0 0 1 1 1 0 Tektin family RasGAP PF00616.14 ETO16856.1 - 0.15 11.7 0.5 0.17 11.5 0.3 1.0 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase IncA PF04156.9 ETO16856.1 - 0.22 11.0 2.2 0.26 10.8 1.5 1.1 1 0 0 1 1 1 0 IncA protein Herpes_BBRF1 PF04793.7 ETO16857.1 - 0.07 11.8 0.4 0.091 11.5 0.3 1.2 1 0 0 1 1 1 0 BRRF1-like protein PhoU_div PF01865.11 ETO16857.1 - 0.15 11.2 4.1 0.29 10.2 2.8 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF47 Spore_SspJ PF09575.5 ETO16857.1 - 2.4 8.4 6.0 4.3 7.6 0.2 3.1 3 0 0 3 3 3 0 Small spore protein J (Spore_SspJ) WD40 PF00400.27 ETO16858.1 - 1.3e-10 40.6 0.5 7.8e-05 22.4 0.1 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF444 PF04285.7 ETO16858.1 - 0.064 11.8 0.0 0.099 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF444) Tubulin_C PF03953.12 ETO16859.1 - 4.2e-29 101.1 0.0 6.5e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Guanylate_cyc PF00211.15 ETO16860.1 - 0.053 12.8 0.1 0.1 11.9 0.1 1.4 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain BLVR PF06375.6 ETO16860.1 - 1.1 9.0 8.2 1.5 8.5 5.7 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) TAF1D PF15333.1 ETO16860.1 - 1.6 8.4 16.0 0.74 9.5 8.2 1.9 1 1 1 2 2 2 0 TATA box-binding protein-associated factor 1D UCH PF00443.24 ETO16862.1 - 5.4e-20 71.6 0.0 9.4e-19 67.5 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO16862.1 - 0.0031 17.0 0.0 0.0039 16.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1980 PF09323.5 ETO16863.1 - 0.0014 18.3 1.9 0.12 12.1 0.0 3.0 2 1 0 3 3 3 2 Domain of unknown function (DUF1980) DUF1418 PF07214.7 ETO16863.1 - 0.16 11.6 0.2 8.1 6.1 0.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1418) Mucin PF01456.12 ETO16863.1 - 0.95 9.2 24.8 2 8.1 17.2 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2681 PF10883.3 ETO16864.1 - 0.067 13.4 0.3 0.067 13.4 0.2 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF2681) STAT2_C PF12188.3 ETO16864.1 - 0.1 12.3 0.2 1.6 8.5 0.1 2.5 2 0 0 2 2 2 0 Signal transducer and activator of transcription 2 C terminal DUF2457 PF10446.4 ETO16865.1 - 0.011 14.5 26.0 0.011 14.5 18.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 ETO16865.1 - 0.094 11.9 16.3 0.09 12.0 11.3 1.1 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.6 ETO16865.1 - 0.12 11.9 19.2 0.12 11.9 13.3 1.0 1 0 0 1 1 1 0 PPP4R2 Cwf_Cwc_15 PF04889.7 ETO16865.1 - 0.18 11.5 21.5 0.2 11.3 14.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FYDLN_acid PF09538.5 ETO16865.1 - 0.18 12.3 17.2 0.2 12.2 12.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Pox_Ag35 PF03286.9 ETO16865.1 - 0.69 9.3 16.9 0.85 9.1 11.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF1510 PF07423.6 ETO16865.1 - 0.8 9.0 19.6 0.81 9.0 13.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RNA_pol_3_Rpc31 PF11705.3 ETO16865.1 - 1.6 8.6 22.1 2 8.2 15.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.9 ETO16865.1 - 1.6 6.7 17.9 1.5 6.7 12.4 1.0 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.8 ETO16865.1 - 1.7 8.4 20.6 1.6 8.5 14.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 ETO16865.1 - 1.8 6.4 23.9 1.8 6.3 16.5 1.0 1 0 0 1 1 1 0 Nop14-like family DUF3245 PF11595.3 ETO16865.1 - 1.9 8.7 17.7 2.4 8.4 12.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) DUF2076 PF09849.4 ETO16865.1 - 2.1 8.3 14.8 2.1 8.3 10.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Myc_N PF01056.13 ETO16865.1 - 2.2 7.3 8.7 2.5 7.1 6.0 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Cellulose_synt PF03552.9 ETO16865.1 - 2.5 6.3 7.8 2.5 6.3 5.4 1.0 1 0 0 1 1 1 0 Cellulose synthase Daxx PF03344.10 ETO16865.1 - 6 5.2 21.8 6.5 5.1 15.1 1.0 1 0 0 1 1 1 0 Daxx Family DDHD PF02862.12 ETO16865.1 - 7.1 6.3 8.4 7.8 6.2 5.8 1.0 1 0 0 1 1 1 0 DDHD domain Apis_Csd PF11671.3 ETO16865.1 - 8.2 6.2 8.6 9.3 6.0 6.0 1.2 1 0 0 1 1 1 0 Complementary sex determiner protein PA26 PF04636.8 ETO16867.1 - 0.033 12.9 2.2 0.035 12.8 1.5 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Calc_CGRP_IAPP PF00214.14 ETO16867.1 - 0.13 12.2 0.7 0.6 10.1 0.0 2.2 1 1 1 2 2 2 0 Calcitonin / CGRP / IAPP family MMR1 PF08505.5 ETO16867.1 - 0.56 10.2 11.4 0.62 10.0 7.9 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein FLO_LFY PF01698.11 ETO16867.1 - 0.57 8.9 9.0 0.72 8.6 6.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein TMV_coat PF00721.16 ETO16867.1 - 4.4 7.2 7.6 0.35 10.8 1.2 2.1 2 1 0 2 2 2 0 Virus coat protein (TMV like) POTRA_2 PF08479.6 ETO16869.1 - 3.5e-10 39.4 0.1 8.8e-10 38.1 0.1 1.8 1 0 0 1 1 1 1 POTRA domain, ShlB-type Surf_Ag_VNR PF07244.10 ETO16869.1 - 0.0019 18.5 5.5 0.29 11.5 0.2 3.2 4 0 0 4 4 4 2 Surface antigen variable number repeat RhoGAP PF00620.22 ETO16870.1 - 0.0029 17.2 0.0 0.011 15.2 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain WD40 PF00400.27 ETO16871.1 - 1.7e-09 37.2 0.7 0.0007 19.3 0.1 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat HNOBA PF07701.9 ETO16873.1 - 0.16 11.1 3.9 0.2 10.8 2.7 1.1 1 0 0 1 1 1 0 Heme NO binding associated Vfa1 PF08432.5 ETO16873.1 - 0.38 10.7 7.8 0.39 10.7 5.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 U79_P34 PF03064.11 ETO16873.1 - 1.2 8.6 8.5 1.2 8.5 5.9 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 ELL PF10390.4 ETO16873.1 - 1.2 8.3 6.1 1.2 8.2 4.2 1.0 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL DUF1510 PF07423.6 ETO16873.1 - 3.7 6.8 12.7 4.5 6.5 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) YqfQ PF14181.1 ETO16873.1 - 5.4 7.0 9.2 6 6.8 6.3 1.2 1 0 0 1 1 1 0 YqfQ-like protein DevR PF01905.11 ETO16874.1 - 0.034 12.9 0.4 0.044 12.6 0.3 1.1 1 0 0 1 1 1 0 CRISPR-associated negative auto-regulator DevR/Csa2 Endotoxin_M PF00555.14 ETO16874.1 - 0.095 12.5 0.2 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 delta endotoxin DUF155 PF02582.9 ETO16875.1 - 1.5e-09 38.0 0.5 0.00058 19.8 0.1 2.1 2 0 0 2 2 2 2 Uncharacterised ACR, YagE family COG1723 SAM_2 PF07647.12 ETO16875.1 - 4.5e-09 36.0 0.1 8.5e-09 35.1 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO16875.1 - 6.3e-08 32.6 1.3 1.2e-07 31.7 0.9 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) NPCC PF08058.6 ETO16875.1 - 1.5 8.7 4.5 2.4 7.9 3.1 1.3 1 0 0 1 1 1 0 Nuclear pore complex component adh_short_C2 PF13561.1 ETO16876.1 - 1.3e-26 93.8 0.0 1.9e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETO16876.1 - 2.4e-23 82.8 0.0 4.1e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETO16876.1 - 1.1e-06 28.3 0.0 2.6e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 KR domain Methyltransf_18 PF12847.2 ETO16876.1 - 0.00041 20.9 0.0 0.0058 17.1 0.0 2.6 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETO16876.1 - 0.0008 19.7 0.0 0.0021 18.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO16876.1 - 0.00091 18.8 2.3 0.0018 17.8 1.6 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO16876.1 - 0.0034 17.8 0.0 0.018 15.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETO16876.1 - 0.0041 17.5 0.0 0.05 14.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Epimerase PF01370.16 ETO16876.1 - 0.0072 15.7 0.0 0.016 14.6 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF276 PF03434.8 ETO16876.1 - 0.028 13.4 0.7 0.047 12.6 0.5 1.5 1 1 0 1 1 1 0 DUF276 Polysacc_synt_2 PF02719.10 ETO16876.1 - 0.045 12.6 0.3 0.059 12.2 0.2 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DDHD PF02862.12 ETO16877.1 - 0.0085 15.9 0.6 0.015 15.0 0.4 1.3 1 0 0 1 1 1 1 DDHD domain PH_BEACH PF14844.1 ETO16877.1 - 8.7 6.2 6.8 19 5.1 0.9 3.2 3 1 0 4 4 4 0 PH domain associated with Beige/BEACH Rad4 PF03835.10 ETO16879.1 - 0.11 11.9 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain Secretin_N_2 PF07655.8 ETO16879.1 - 0.5 10.7 10.2 1.1 9.6 7.0 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain Apis_Csd PF11671.3 ETO16879.1 - 1.1 9.0 8.9 1.5 8.6 6.2 1.2 1 0 0 1 1 1 0 Complementary sex determiner protein DUF2450 PF10475.4 ETO16880.1 - 1.5e-11 43.7 4.5 2.2e-11 43.2 3.1 1.1 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) SRCR PF00530.13 ETO16880.1 - 0.039 14.2 0.3 0.064 13.5 0.2 1.4 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain DUF3294 PF07957.6 ETO16881.1 - 0.019 14.5 3.2 0.032 13.7 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) DUF2514 PF10721.4 ETO16881.1 - 0.039 13.6 0.2 0.059 13.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Mu-like_Pro PF10123.4 ETO16881.1 - 0.064 12.7 1.0 0.089 12.2 0.7 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein Cytochrom_C1 PF02167.10 ETO16882.1 - 6.5e-47 160.0 3.9 1e-31 110.2 0.0 3.0 2 1 0 2 2 2 2 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 ETO16882.1 - 0.00048 20.2 0.0 0.0028 17.7 0.0 2.3 2 1 0 2 2 2 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 ETO16882.1 - 0.048 14.4 0.0 0.14 13.0 0.0 1.8 1 0 0 1 1 1 0 Cytochrome c DUF2207 PF09972.4 ETO16883.1 - 4.6 5.7 13.5 5 5.5 9.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Bap31 PF05529.7 ETO16884.1 - 0.053 12.9 3.1 0.062 12.7 2.2 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like 7TM_GPCR_Srw PF10324.4 ETO16884.1 - 0.19 10.7 0.8 0.25 10.4 0.6 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Haem_bd PF14376.1 ETO16886.1 - 0.49 10.0 3.9 0.92 9.1 2.7 1.5 1 0 0 1 1 1 0 Haem-binding domain zf-C3HC4_2 PF13923.1 ETO16887.1 - 0.0005 20.0 2.5 0.0005 20.0 1.7 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO16887.1 - 0.00061 19.3 1.2 0.0017 17.9 0.9 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Apt1 PF10351.4 ETO16887.1 - 0.00063 18.7 0.6 0.00079 18.3 0.4 1.0 1 0 0 1 1 1 1 Golgi-body localisation protein domain FYVE PF01363.16 ETO16887.1 - 0.023 14.6 4.9 0.037 13.9 3.4 1.6 1 1 0 1 1 1 0 FYVE zinc finger DUF3279 PF11682.3 ETO16887.1 - 0.051 13.1 2.0 0.081 12.4 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3279) Methyltransf_12 PF08242.7 ETO16887.1 - 0.18 12.3 1.0 0.43 11.0 0.7 1.6 1 0 0 1 1 1 0 Methyltransferase domain zf-RING_5 PF14634.1 ETO16887.1 - 2.4 7.9 9.7 7 6.4 6.7 1.9 1 1 0 1 1 1 0 zinc-RING finger domain DUF3439 PF11921.3 ETO16887.1 - 8.3 6.1 8.6 2 8.2 1.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3439) Macoilin PF09726.4 ETO16887.1 - 8.8 4.4 13.2 1.4 7.1 3.9 1.9 2 0 0 2 2 2 0 Transmembrane protein Eapp_C PF10238.4 ETO16887.1 - 9.9 6.0 11.6 2.3 8.0 2.4 2.5 2 0 0 2 2 2 0 E2F-associated phosphoprotein Pex14_N PF04695.8 ETO16888.1 - 5.7 6.9 9.6 7.4 6.6 6.7 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pox_Ag35 PF03286.9 ETO16888.1 - 5.9 6.3 7.8 6.9 6.1 5.4 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Zip PF02535.17 ETO16888.1 - 6.3 5.6 5.5 7.3 5.4 3.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2076 PF09849.4 ETO16888.1 - 7.4 6.5 10.8 8.6 6.3 7.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) HAD_2 PF13419.1 ETO16890.1 - 3.5e-13 50.1 0.0 6.1e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 ETO16890.1 - 4.1e-06 27.3 0.0 6.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ETO16890.1 - 1.8e-05 24.3 0.0 5.2e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like E1-E2_ATPase PF00122.15 ETO16891.1 - 1.1e-40 139.1 2.9 1.1e-40 139.1 2.0 2.2 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 ETO16891.1 - 2.4e-23 83.6 0.0 1.1e-22 81.5 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETO16891.1 - 2.8e-12 47.1 0.1 5.2e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 ETO16891.1 - 1.9e-07 31.0 0.0 7.4e-07 29.2 0.0 2.1 1 0 0 1 1 1 1 Heavy-metal-associated domain ATPase-cat_bd PF12156.3 ETO16891.1 - 2.6e-07 31.0 4.9 6.3e-07 29.8 3.4 1.6 1 0 0 1 1 1 1 Putative metal-binding domain of cation transport ATPase Hydrolase_3 PF08282.7 ETO16891.1 - 1.1 8.7 8.8 0.11 12.0 0.1 2.8 3 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase Trigger_N PF05697.8 ETO16892.1 - 3.2e-33 114.5 3.4 1.1e-32 112.7 2.4 2.0 1 0 0 1 1 1 1 Bacterial trigger factor protein (TF) Trigger_C PF05698.9 ETO16892.1 - 7e-29 100.7 15.3 1.1e-27 96.8 5.2 3.0 3 0 0 3 3 3 2 Bacterial trigger factor protein (TF) C-terminus TraC PF07820.7 ETO16892.1 - 0.041 14.0 1.8 3.2 8.0 0.1 3.5 3 0 0 3 3 3 0 TraC-like protein DIE2_ALG10 PF04922.7 ETO16893.1 - 4.9e-27 94.9 4.2 4.3e-19 68.8 0.1 2.1 2 0 0 2 2 2 2 DIE2/ALG10 family DUF2627 PF11118.3 ETO16893.1 - 0.16 12.1 2.4 0.22 11.6 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2627) PH PF00169.24 ETO16896.1 - 0.0072 16.5 3.2 0.14 12.3 0.0 3.1 3 0 0 3 3 3 1 PH domain DUF912 PF06024.7 ETO16896.1 - 0.019 14.9 3.8 2.3 8.3 0.0 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Helicase_IV_N PF12462.3 ETO16896.1 - 0.031 13.9 0.3 0.082 12.5 0.2 1.7 1 1 1 2 2 2 0 DNA helicase IV / RNA helicase N terminal DUF2743 PF10899.3 ETO16896.1 - 0.053 12.8 4.8 0.086 12.2 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2743) DUF1192 PF06698.6 ETO16896.1 - 0.056 13.2 0.2 0.43 10.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Borrelia_REV PF03978.8 ETO16896.1 - 0.23 11.1 14.5 1.4 8.6 5.0 2.5 2 0 0 2 2 2 0 Borrelia burgdorferi REV protein Amnionless PF14828.1 ETO16896.1 - 0.25 9.8 5.4 3.7 5.9 0.0 3.0 2 1 0 3 3 3 0 Amnionless CENP-H PF05837.7 ETO16896.1 - 1.5 9.0 7.4 1.6 8.9 0.6 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF2644 PF10841.3 ETO16897.1 - 0.04 13.9 0.2 0.04 13.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2644) WD40 PF00400.27 ETO16898.1 - 2.2e-66 217.5 30.3 6.3e-12 44.8 0.5 6.7 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO16898.1 - 1.6e-08 33.1 8.4 0.0016 16.6 0.7 4.7 1 1 2 4 4 4 4 Nucleoporin Nup120/160 DUF2431 PF10354.4 ETO16899.1 - 2.2e-11 43.9 0.5 2.2e-11 43.9 0.3 1.7 2 1 0 2 2 2 1 Domain of unknown function (DUF2431) Methyltransf_26 PF13659.1 ETO16899.1 - 0.0015 18.5 0.0 0.0027 17.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain ABC2_membrane_4 PF12730.2 ETO16900.1 - 0.00088 18.5 0.7 0.001 18.2 0.5 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein Thioredoxin_7 PF13899.1 ETO16901.1 - 9.8e-11 41.5 0.1 4.5e-10 39.4 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like DsbD PF02683.10 ETO16901.1 - 2.8e-09 36.9 18.5 2.8e-09 36.9 12.9 2.0 1 1 1 2 2 2 1 Cytochrome C biogenesis protein transmembrane region Thioredoxin PF00085.15 ETO16901.1 - 0.0011 18.5 0.1 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredox_DsbH PF03190.10 ETO16901.1 - 0.041 13.6 0.5 0.079 12.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF255 tRNA-synt_1d PF00750.14 ETO16903.1 - 0.031 13.1 1.3 0.032 13.0 0.9 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (R) DUF1327 PF07041.6 ETO16903.1 - 0.063 13.1 0.1 0.08 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1327) DEP PF00610.16 ETO16905.1 - 5.9e-37 125.2 3.9 9.6e-19 66.9 0.1 4.6 5 0 0 5 5 5 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF2457 PF10446.4 ETO16906.1 - 0.025 13.3 2.3 0.028 13.1 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 ETO16906.1 - 4.1 6.5 12.5 5.8 6.0 8.6 1.2 1 0 0 1 1 1 0 NOA36 protein DUF2076 PF09849.4 ETO16906.1 - 8.7 6.3 12.3 12 5.8 8.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) P2X_receptor PF00864.14 ETO16907.1 - 1.8e-10 40.0 0.0 2.5e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 ATP P2X receptor Trypan_PARP PF05887.6 ETO16907.1 - 0.044 13.6 1.4 0.051 13.3 1.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.6 ETO16907.1 - 1.9 8.2 11.3 2.6 7.8 7.8 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Abhydrolase_5 PF12695.2 ETO16908.1 - 4.8e-15 55.5 0.0 6.7e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETO16908.1 - 5.9e-11 42.6 0.0 3.3e-09 36.9 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 ETO16908.1 - 7.2e-08 32.1 0.0 3.7e-06 26.5 0.0 2.1 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.13 ETO16908.1 - 3.5e-06 26.4 0.0 0.067 12.4 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 ETO16908.1 - 4e-06 26.5 0.0 0.0046 16.5 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold BAAT_C PF08840.6 ETO16908.1 - 1e-05 25.3 0.0 0.16 11.6 0.0 2.7 2 1 1 3 3 3 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 ETO16908.1 - 0.00059 19.4 0.0 0.00088 18.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold UPF0227 PF05728.7 ETO16908.1 - 0.0015 18.2 0.0 0.0033 17.1 0.0 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) Peptidase_S9 PF00326.16 ETO16908.1 - 0.002 17.4 0.0 0.004 16.3 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF1749 PF08538.5 ETO16908.1 - 0.0084 15.0 0.0 1.7 7.4 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1749) AXE1 PF05448.7 ETO16908.1 - 0.019 13.5 0.0 0.032 12.7 0.0 1.4 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Esterase PF00756.15 ETO16908.1 - 0.019 14.4 0.0 0.026 13.9 0.0 1.4 1 1 0 1 1 1 0 Putative esterase FSH1 PF03959.8 ETO16908.1 - 0.026 13.9 0.0 0.076 12.4 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF829 PF05705.9 ETO16908.1 - 0.05 13.2 0.0 0.11 12.1 0.0 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Lipase_3 PF01764.20 ETO16908.1 - 0.061 12.9 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_9 PF10081.4 ETO16908.1 - 0.066 11.8 0.0 0.097 11.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family DUF2974 PF11187.3 ETO16908.1 - 0.083 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Esterase_phd PF10503.4 ETO16908.1 - 0.085 12.0 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase PPO1_DWL PF12142.3 ETO16909.1 - 0.0034 16.8 0.2 0.01 15.3 0.1 1.8 1 0 0 1 1 1 1 Polyphenol oxidase middle domain EF-hand_7 PF13499.1 ETO16909.1 - 0.0037 17.3 1.0 0.0037 17.3 0.7 2.3 3 0 0 3 3 3 1 EF-hand domain pair AA_permease PF00324.16 ETO16909.1 - 0.026 12.8 6.4 0.039 12.2 4.5 1.2 1 0 0 1 1 1 0 Amino acid permease Dpy19 PF10034.4 ETO16909.1 - 0.059 11.5 0.0 0.099 10.7 0.0 1.3 1 1 0 1 1 1 0 Q-cell neuroblast polarisation EF-hand_6 PF13405.1 ETO16909.1 - 0.068 13.0 0.0 0.068 13.0 0.0 3.5 4 0 0 4 4 4 0 EF-hand domain DUF1461 PF07314.6 ETO16909.1 - 0.1 12.3 5.3 0.19 11.4 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) IncA PF04156.9 ETO16909.1 - 0.15 11.6 3.3 0.3 10.6 2.3 1.8 1 1 0 1 1 1 0 IncA protein Shisa PF13908.1 ETO16909.1 - 1.6 8.8 5.9 2.6 8.1 4.1 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 ETO16909.1 - 1.7 9.0 6.1 0.95 9.8 2.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Baculo_11_kDa PF06143.6 ETO16909.1 - 2.3 7.6 11.2 6.2 6.2 7.7 1.8 1 0 0 1 1 1 0 Baculovirus 11 kDa family TRP PF06011.7 ETO16909.1 - 4 5.8 7.1 7.2 5.0 4.9 1.3 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel DUF4446 PF14584.1 ETO16909.1 - 8.9 6.1 13.8 0.58 9.9 2.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) Ion_trans PF00520.26 ETO16910.1 - 7.8e-12 44.8 12.1 7.8e-12 44.8 8.4 2.0 2 1 0 2 2 2 1 Ion transport protein PKD_channel PF08016.7 ETO16910.1 - 4.4e-11 41.8 11.5 8.7e-11 40.8 7.9 1.4 1 0 0 1 1 1 1 Polycystin cation channel TraP PF07296.6 ETO16910.1 - 0.34 9.8 3.5 0.26 10.2 0.1 2.3 2 0 0 2 2 2 0 TraP protein SAM_1 PF00536.25 ETO16911.1 - 1.1e-19 70.3 0.1 1.4e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO16911.1 - 1.3e-17 63.3 0.1 1.7e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 ETO16911.1 - 7.4e-05 22.4 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Cut8_N PF14482.1 ETO16911.1 - 0.0092 15.9 0.4 1.1 9.2 1.0 2.2 2 0 0 2 2 2 1 Cut8 proteasome-binding domain Ste50p-SAM PF09235.5 ETO16911.1 - 0.042 13.8 0.1 0.066 13.2 0.0 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Abhydrolase_6 PF12697.2 ETO16912.1 - 2.4e-28 99.6 0.0 3.5e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETO16912.1 - 1.4e-18 67.3 0.0 3e-17 62.9 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETO16912.1 - 2.7e-11 43.4 0.2 9.2e-11 41.6 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 ETO16912.1 - 4.3e-07 28.7 0.1 7.5e-07 27.9 0.1 1.3 1 0 0 1 1 1 1 Ndr family Ser_hydrolase PF06821.8 ETO16912.1 - 6.5e-05 22.6 0.3 0.21 11.1 0.1 2.8 2 1 1 3 3 3 2 Serine hydrolase Glyco_hydro_42 PF02449.10 ETO16912.1 - 0.0037 16.4 0.0 0.006 15.7 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase Abhydrolase_8 PF06259.7 ETO16912.1 - 0.0079 15.7 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase Esterase PF00756.15 ETO16912.1 - 0.035 13.5 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.16 ETO16912.1 - 0.051 12.7 0.0 2.1 7.5 0.0 2.5 1 1 1 2 2 2 0 Prolyl oligopeptidase family DUF2269 PF10027.4 ETO16912.1 - 0.19 11.4 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) DUF2233 PF09992.4 ETO16913.1 - 1.3e-21 77.4 0.0 3.6e-20 72.6 0.0 2.4 1 1 0 1 1 1 1 Predicted periplasmic protein (DUF2233) Tubulin PF00091.20 ETO16914.1 - 2.1e-20 73.5 0.0 3.7e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO16914.1 - 5.7e-19 68.3 0.0 1.2e-18 67.3 0.0 1.5 1 1 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.1 ETO16914.1 - 0.13 11.1 0.1 0.26 10.1 0.0 1.5 2 0 0 2 2 2 0 Tubulin like RRM_1 PF00076.17 ETO16915.1 - 0.0049 16.4 0.0 0.016 14.7 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_C2 PF00648.16 ETO16918.1 - 1.5e-27 96.3 0.0 1.9e-27 96.0 0.0 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease Ion_trans PF00520.26 ETO16919.1 - 1e-10 41.2 5.2 1.9e-10 40.3 3.6 1.5 1 0 0 1 1 1 1 Ion transport protein PsbI PF02532.9 ETO16919.1 - 0.83 9.3 4.7 2 8.1 3.2 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Rsm22 PF09243.5 ETO16920.1 - 1e-12 47.7 0.0 2.6e-09 36.5 0.0 2.1 1 1 1 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 DEP PF00610.16 ETO16922.1 - 9.3e-11 41.3 0.2 2.3e-10 40.0 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF3166 PF11365.3 ETO16923.1 - 0.0088 16.4 1.2 0.015 15.7 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3166) TPR_MLP1_2 PF07926.7 ETO16923.1 - 0.0093 15.7 22.1 0.25 11.0 8.0 2.3 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein DUF2353 PF09789.4 ETO16923.1 - 0.015 14.5 15.6 0.026 13.7 10.8 1.5 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Macoilin PF09726.4 ETO16923.1 - 0.035 12.4 13.8 0.04 12.1 9.6 1.0 1 0 0 1 1 1 0 Transmembrane protein TBPIP PF07106.8 ETO16923.1 - 0.05 13.1 13.2 0.074 12.6 9.1 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 ETO16923.1 - 0.056 13.0 20.3 0.079 12.5 14.0 1.2 1 0 0 1 1 1 0 IncA protein Hat1_N PF10394.4 ETO16923.1 - 0.088 12.8 1.0 0.18 11.8 0.0 1.8 1 1 1 2 2 2 0 Histone acetyl transferase HAT1 N-terminus AIP3 PF03915.8 ETO16923.1 - 0.14 11.0 11.8 0.17 10.7 7.4 1.6 1 1 0 1 1 1 0 Actin interacting protein 3 TEX19 PF15553.1 ETO16923.1 - 0.19 11.5 1.4 0.23 11.3 1.0 1.3 1 0 0 1 1 1 0 Testis-expressed protein 19 Cep57_CLD_2 PF14197.1 ETO16923.1 - 0.21 11.5 12.4 9.4 6.2 7.4 2.8 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 IFT20 PF14931.1 ETO16923.1 - 0.23 11.3 11.0 0.13 12.1 6.1 1.6 1 1 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Fmp27_WPPW PF10359.4 ETO16923.1 - 0.23 9.8 10.2 0.28 9.5 7.1 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain CENP-F_leu_zip PF10473.4 ETO16923.1 - 0.24 11.2 14.4 0.11 12.2 6.5 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Striatin PF08232.7 ETO16923.1 - 0.27 11.5 12.1 0.078 13.2 5.7 1.9 1 1 1 2 2 2 0 Striatin family APG6 PF04111.7 ETO16923.1 - 0.28 10.1 17.7 0.26 10.3 11.7 1.4 2 0 0 2 2 2 0 Autophagy protein Apg6 Atg14 PF10186.4 ETO16923.1 - 0.29 10.0 15.4 0.54 9.1 10.7 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 UPF0184 PF03670.8 ETO16923.1 - 0.36 11.0 13.5 0.074 13.2 4.1 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) HAUS6_N PF14661.1 ETO16923.1 - 0.4 9.9 10.2 0.48 9.7 7.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF869 PF05911.6 ETO16923.1 - 0.44 8.7 12.5 0.5 8.5 8.7 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Mnd1 PF03962.10 ETO16923.1 - 0.44 10.1 19.1 0.28 10.8 7.8 2.3 1 1 1 2 2 2 0 Mnd1 family DUF3584 PF12128.3 ETO16923.1 - 0.47 7.7 16.1 0.51 7.5 11.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CENP-Q PF13094.1 ETO16923.1 - 0.63 10.0 17.1 0.32 11.0 10.1 1.6 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Fib_alpha PF08702.5 ETO16923.1 - 0.65 10.1 17.7 0.13 12.3 8.7 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family KGK PF08872.5 ETO16923.1 - 1.1 9.4 4.8 0.76 9.9 1.7 1.8 1 1 1 2 2 2 0 KGK domain Exonuc_VII_L PF02601.10 ETO16923.1 - 1.2 8.2 12.8 1.4 7.9 8.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tropomyosin PF00261.15 ETO16923.1 - 1.3 8.0 14.7 0.28 10.2 5.9 1.8 1 1 1 2 2 2 0 Tropomyosin AbiH PF14253.1 ETO16923.1 - 1.4 8.4 9.6 1.8 8.1 6.7 1.2 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH SPX PF03105.14 ETO16923.1 - 1.5 8.5 12.0 1.7 8.3 8.3 1.1 1 0 0 1 1 1 0 SPX domain V_ATPase_I PF01496.14 ETO16923.1 - 1.6 6.5 9.5 1.8 6.3 6.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cep57_MT_bd PF06657.8 ETO16923.1 - 1.7 8.6 10.3 0.24 11.3 2.0 2.7 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Tropomyosin_1 PF12718.2 ETO16923.1 - 1.9 8.3 19.7 0.26 11.1 8.2 2.2 1 1 0 2 2 2 0 Tropomyosin like HALZ PF02183.13 ETO16923.1 - 2.7 7.7 10.5 1.8 8.3 1.4 2.8 2 1 0 2 2 2 0 Homeobox associated leucine zipper CASP_C PF08172.7 ETO16923.1 - 3.2 6.7 14.3 12 4.8 9.9 1.9 1 1 0 1 1 1 0 CASP C terminal DUF1525 PF07511.6 ETO16923.1 - 3.5 7.6 10.6 5.8 6.9 7.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1525) SlyX PF04102.7 ETO16923.1 - 3.5 8.0 18.6 13 6.2 8.2 2.5 1 1 1 2 2 2 0 SlyX ADIP PF11559.3 ETO16923.1 - 3.7 7.4 25.3 1 9.2 8.6 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Suf PF05843.9 ETO16923.1 - 4.2 7.0 10.7 4.7 6.8 7.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) HlyD PF00529.15 ETO16923.1 - 9.2 5.4 19.2 10 5.3 13.3 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Syntaxin PF00804.20 ETO16923.1 - 9.9 6.3 17.5 71 3.6 12.2 2.2 1 1 0 1 1 1 0 Syntaxin CSTF2_hinge PF14327.1 ETO16924.1 - 1.3e-13 50.8 2.5 1.3e-13 50.8 1.7 3.0 4 1 0 4 4 4 1 Hinge domain of cleavage stimulation factor subunit 2 DnaG_DnaB_bind PF08278.6 ETO16924.1 - 0.09 12.9 2.4 0.17 12.0 0.2 2.3 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding DUF1804 PF08822.6 ETO16924.1 - 0.17 11.6 1.9 0.27 10.9 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) H_PPase PF03030.11 ETO16925.1 - 1.5e-209 697.6 15.7 2e-209 697.2 10.9 1.2 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase UPF0154 PF03672.8 ETO16925.1 - 8.6 6.0 7.3 6 6.5 0.1 3.5 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0154) WD40 PF00400.27 ETO16926.1 - 5.1e-82 267.0 19.0 4.2e-14 51.7 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO16926.1 - 7.3e-10 37.6 6.0 0.059 11.4 0.0 5.1 1 1 4 5 5 5 5 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO16926.1 - 7.8e-08 32.2 0.2 0.039 13.6 0.0 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO16926.1 - 6.3e-07 28.0 0.9 0.0017 16.7 0.0 3.1 2 1 1 3 3 3 2 Cytochrome D1 heme domain DUF3601 PF12208.3 ETO16926.1 - 0.0043 16.9 0.0 3.4 7.6 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3601) Resistin PF06954.6 ETO16926.1 - 0.013 15.7 0.8 52 4.2 0.0 4.6 4 2 1 5 5 5 0 Resistin DUF1258 PF06869.7 ETO16926.1 - 0.018 14.1 0.3 6.6 5.7 0.0 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF1258) Nucleoporin_N PF08801.6 ETO16926.1 - 0.022 13.5 7.1 6.4 5.3 0.2 4.5 1 1 2 3 3 3 0 Nup133 N terminal like Mid2 PF04478.7 ETO16926.1 - 0.025 13.9 0.4 6.4 6.1 0.0 3.5 2 1 2 4 4 4 0 Mid2 like cell wall stress sensor UN_NPL4 PF11543.3 ETO16926.1 - 0.031 14.5 0.1 1.8 8.9 0.0 3.3 3 1 1 4 4 4 0 Nuclear pore localisation protein NPL4 DPPIV_N PF00930.16 ETO16926.1 - 0.08 11.5 0.3 1.4 7.4 0.0 2.9 2 1 2 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Proteasome_A_N PF10584.4 ETO16926.1 - 1.7 8.0 3.5 17 4.8 0.0 3.2 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature PHTB1_C PF14728.1 ETO16929.1 - 0.064 12.0 1.1 0.078 11.7 0.8 1.1 1 0 0 1 1 1 0 PTHB1 C-terminus Myosin_tail_1 PF01576.14 ETO16929.1 - 0.073 10.7 5.8 0.095 10.4 4.0 1.1 1 0 0 1 1 1 0 Myosin tail IncA PF04156.9 ETO16929.1 - 0.1 12.1 3.6 0.14 11.7 2.5 1.2 1 0 0 1 1 1 0 IncA protein HALZ PF02183.13 ETO16929.1 - 0.11 12.1 0.5 0.11 12.1 0.3 2.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper bZIP_1 PF00170.16 ETO16929.1 - 0.57 10.1 5.5 1.1 9.2 0.1 2.3 1 1 1 2 2 2 0 bZIP transcription factor DUF724 PF05266.9 ETO16929.1 - 0.82 9.2 6.6 1.1 8.8 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) BLOC1_2 PF10046.4 ETO16929.1 - 1.7 8.8 8.5 4.9 7.3 5.9 1.7 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Borrelia_REV PF03978.8 ETO16930.1 - 0.0085 15.8 1.9 0.0085 15.8 1.3 1.6 1 1 0 1 1 1 1 Borrelia burgdorferi REV protein SlyX PF04102.7 ETO16930.1 - 0.014 15.7 7.5 0.56 10.6 1.5 2.5 2 0 0 2 2 2 0 SlyX DivIC PF04977.10 ETO16930.1 - 0.018 14.5 0.7 0.018 14.5 0.5 2.6 3 0 0 3 3 3 0 Septum formation initiator TMF_TATA_bd PF12325.3 ETO16930.1 - 0.022 14.4 11.1 0.21 11.3 1.6 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FliJ PF02050.11 ETO16930.1 - 0.081 12.9 11.1 0.58 10.2 0.9 2.6 2 1 0 2 2 2 0 Flagellar FliJ protein Atg14 PF10186.4 ETO16930.1 - 0.11 11.4 12.5 0.044 12.7 1.2 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ADIP PF11559.3 ETO16930.1 - 0.38 10.6 13.6 0.13 12.1 1.6 2.5 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.5 ETO16930.1 - 0.47 10.5 14.0 0.86 9.7 3.4 2.4 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF2443 PF10398.4 ETO16930.1 - 0.85 9.4 4.1 7.2 6.4 0.1 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2443) DUF948 PF06103.6 ETO16930.1 - 0.97 9.3 3.2 1.9 8.3 0.1 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4446 PF14584.1 ETO16930.1 - 1.4 8.7 9.2 0.17 11.6 1.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) IFP_35_N PF07334.8 ETO16930.1 - 1.6 8.7 7.0 1.5 8.8 2.4 2.7 2 1 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus EMP24_GP25L PF01105.19 ETO16930.1 - 1.6 8.3 8.2 3.2 7.4 0.9 2.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Bacillus_HBL PF05791.6 ETO16930.1 - 1.6 8.0 8.3 0.24 10.7 0.4 2.6 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Leu_zip PF15294.1 ETO16930.1 - 2 7.4 15.3 0.042 12.9 2.7 2.6 2 1 0 2 2 2 0 Leucine zipper DUF4140 PF13600.1 ETO16930.1 - 2.8 8.4 6.6 1.8 9.0 0.9 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Phage_GP20 PF06810.6 ETO16930.1 - 3.5 7.0 9.9 8.4 5.8 0.7 2.9 3 0 0 3 3 3 0 Phage minor structural protein GP20 OmpH PF03938.9 ETO16930.1 - 3.7 7.4 11.2 0.63 9.9 1.2 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) CENP-Q PF13094.1 ETO16930.1 - 4.9 7.1 10.9 0.14 12.1 1.7 2.3 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit TPR_MLP1_2 PF07926.7 ETO16930.1 - 5.2 6.8 14.5 0.22 11.2 1.6 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Syntaxin-6_N PF09177.6 ETO16930.1 - 6.3 7.2 9.3 2.3 8.6 0.7 2.9 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DUF342 PF03961.8 ETO16930.1 - 9.5 4.5 13.6 0.42 8.9 1.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) G-alpha PF00503.15 ETO16931.1 - 1.5e-46 158.9 13.5 1.6e-46 158.7 9.4 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO16931.1 - 3.5e-09 36.1 0.5 7e-09 35.1 0.3 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family DUF3072 PF11272.3 ETO16931.1 - 0.17 11.5 0.1 0.31 10.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) Sec7_N PF12783.2 ETO16933.1 - 1e-08 34.8 0.0 2.3e-06 27.1 0.0 2.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal zf-HIT PF04438.11 ETO16933.1 - 5.6e-05 22.7 1.5 0.0001 21.8 1.0 1.4 1 0 0 1 1 1 1 HIT zinc finger Neur_chan_memb PF02932.11 ETO16933.1 - 0.77 9.6 4.4 1.2 8.9 3.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4435 PF14491.1 ETO16934.1 - 0.029 14.2 0.5 0.038 13.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4435) UspB PF10625.4 ETO16934.1 - 0.053 13.2 0.5 0.081 12.7 0.3 1.2 1 0 0 1 1 1 0 Universal stress protein B (UspB) DUF448 PF04296.8 ETO16935.1 - 0.01 15.4 0.1 0.02 14.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF448) HGTP_anticodon2 PF12745.2 ETO16935.1 - 0.067 12.3 8.3 0.076 12.1 5.7 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF2636 PF11120.3 ETO16935.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2636) DUF3292 PF11696.3 ETO16935.1 - 0.4 8.5 4.3 0.4 8.4 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Tom22 PF04281.8 ETO16935.1 - 0.47 9.9 5.4 0.64 9.5 3.7 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 LMBR1 PF04791.11 ETO16935.1 - 0.56 8.7 3.0 0.64 8.5 2.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein CDC45 PF02724.9 ETO16935.1 - 0.71 7.8 5.3 0.84 7.5 3.7 1.0 1 0 0 1 1 1 0 CDC45-like protein XAP5 PF04921.9 ETO16935.1 - 0.75 9.3 8.8 0.95 8.9 6.1 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator Vfa1 PF08432.5 ETO16935.1 - 0.8 9.7 11.4 0.98 9.4 7.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Allexi_40kDa PF05549.6 ETO16935.1 - 1 8.6 3.8 1.2 8.4 2.6 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Frigida PF07899.6 ETO16935.1 - 2.5 6.7 9.8 3.1 6.4 6.8 1.1 1 0 0 1 1 1 0 Frigida-like protein Fmp27 PF10344.4 ETO16935.1 - 3.9 5.0 10.5 4.4 4.8 7.3 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 vATP-synt_AC39 PF01992.11 ETO16936.1 - 2.3e-15 56.5 0.0 2.4e-15 56.5 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit UDPGT PF00201.13 ETO16936.1 - 0.089 11.3 0.1 0.098 11.1 0.0 1.0 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase DUF2709 PF10915.3 ETO16936.1 - 0.093 11.7 0.2 0.13 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2709) SR-25 PF10500.4 ETO16937.1 - 0.0045 16.4 7.8 0.0045 16.4 5.4 3.6 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein DUF2713 PF10897.3 ETO16937.1 - 0.015 14.5 0.2 0.18 11.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2713) Pheromone PF08015.6 ETO16937.1 - 0.63 10.9 11.1 0.22 12.3 5.3 2.1 2 0 0 2 2 2 0 Fungal mating-type pheromone APG17 PF04108.7 ETO16938.1 - 0.0099 14.7 0.2 0.01 14.6 0.2 1.2 1 0 0 1 1 1 1 Autophagy protein Apg17 RRF PF01765.14 ETO16938.1 - 0.01 15.3 0.7 0.017 14.6 0.5 1.3 1 0 0 1 1 1 0 Ribosome recycling factor DUF1664 PF07889.7 ETO16938.1 - 0.02 14.6 1.0 0.034 13.9 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) GrpE PF01025.14 ETO16938.1 - 0.038 13.5 1.8 0.079 12.4 1.2 1.5 1 0 0 1 1 1 0 GrpE Vps5 PF09325.5 ETO16938.1 - 0.043 13.0 1.5 0.078 12.2 1.0 1.3 1 0 0 1 1 1 0 Vps5 C terminal like DUF1845 PF08900.6 ETO16938.1 - 0.063 12.5 0.9 0.098 11.9 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) AKNA PF12443.3 ETO16938.1 - 0.077 13.0 1.0 0.077 13.0 0.7 1.9 2 0 0 2 2 2 0 AT-hook-containing transcription factor Atg14 PF10186.4 ETO16938.1 - 0.16 10.9 1.2 0.24 10.3 0.8 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 T4SS PF07996.6 ETO16938.1 - 0.38 10.5 2.5 0.41 10.4 1.0 1.6 1 1 0 1 1 1 0 Type IV secretion system proteins DUF2951 PF11166.3 ETO16938.1 - 0.48 10.2 3.2 0.28 11.0 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) DUF4546 PF15079.1 ETO16938.1 - 0.71 8.9 4.3 1.2 8.2 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4546) DUF4618 PF15397.1 ETO16938.1 - 0.81 8.9 5.5 0.18 11.0 1.6 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DivIC PF04977.10 ETO16938.1 - 0.95 8.9 4.5 2.2 7.8 3.1 1.6 1 0 0 1 1 1 0 Septum formation initiator Phage_GP20 PF06810.6 ETO16938.1 - 2.4 7.5 9.9 0.11 11.8 2.7 1.8 2 0 0 2 2 2 0 Phage minor structural protein GP20 Tropomyosin PF00261.15 ETO16938.1 - 2.5 7.1 10.9 0.07 12.2 1.8 2.0 2 0 0 2 2 2 0 Tropomyosin Prefoldin_2 PF01920.15 ETO16938.1 - 3.2 7.5 8.7 0.43 10.3 3.0 1.8 2 0 0 2 2 2 0 Prefoldin subunit Cortex-I_coil PF09304.5 ETO16938.1 - 3.3 7.7 8.9 0.49 10.4 3.0 1.8 2 1 0 2 2 2 0 Cortexillin I, coiled coil Med4 PF10018.4 ETO16938.1 - 8.6 5.7 7.3 1.1 8.5 1.6 1.8 1 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Atg8 PF02991.11 ETO16940.1 - 0.053 13.4 0.2 0.56 10.2 0.1 1.9 1 1 1 2 2 2 0 Autophagy protein Atg8 ubiquitin like Peptidase_C97 PF05903.9 ETO16941.1 - 0.013 15.2 0.1 0.028 14.2 0.1 1.5 1 0 0 1 1 1 0 PPPDE putative peptidase domain LRAT PF04970.8 ETO16941.1 - 0.014 15.3 0.0 0.085 12.8 0.0 2.2 2 0 0 2 2 2 0 Lecithin retinol acyltransferase MFS_1 PF07690.11 ETO16942.1 - 9.9e-10 37.6 41.2 1.6e-06 27.1 8.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2721 PF11026.3 ETO16942.1 - 0.075 12.6 0.1 0.075 12.6 0.1 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF2721) Exo_endo_phos PF03372.18 ETO16943.1 - 0.00039 20.4 0.0 0.00052 20.0 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Cation_efflux PF01545.16 ETO16943.1 - 0.03 13.4 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 Cation efflux family Atrophin-1 PF03154.10 ETO16944.1 - 0.0014 16.9 3.0 0.0022 16.2 2.1 1.2 1 0 0 1 1 1 1 Atrophin-1 family Menin PF05053.8 ETO16944.1 - 2.1 6.4 7.6 0.72 7.9 1.0 2.1 2 0 0 2 2 2 0 Menin CBS PF00571.23 ETO16947.1 - 7.4e-07 28.8 0.0 9e-06 25.3 0.0 2.3 1 1 1 2 2 2 1 CBS domain RVT_1 PF00078.22 ETO16947.1 - 0.043 13.1 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3798 PF12683.2 ETO16947.1 - 0.05 12.6 1.3 0.069 12.2 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) TetR_C_8 PF14278.1 ETO16947.1 - 0.052 13.9 0.7 0.14 12.5 0.1 1.9 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region RVT_3 PF13456.1 ETO16947.1 - 0.15 11.8 0.2 0.15 11.8 0.1 1.9 2 1 0 3 3 3 0 Reverse transcriptase-like NOA36 PF06524.7 ETO16948.1 - 6.6 5.9 6.6 6.8 5.8 4.5 1.1 1 0 0 1 1 1 0 NOA36 protein Oxidored_q2 PF00420.19 ETO16949.1 - 0.026 14.1 2.6 0.026 14.1 1.8 2.0 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF4131 PF13567.1 ETO16949.1 - 0.35 10.2 9.6 1.2 8.5 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) NMN_transporter PF04973.7 ETO16949.1 - 0.78 9.1 16.5 0.079 12.4 2.7 2.3 2 0 0 2 2 2 0 Nicotinamide mononucleotide transporter DUF485 PF04341.7 ETO16949.1 - 1.3 8.7 13.5 0.81 9.4 4.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Mito_carr PF00153.22 ETO16951.1 - 3.4e-38 129.2 4.2 2.1e-16 59.3 0.0 3.9 2 2 1 3 3 3 3 Mitochondrial carrier protein G-alpha PF00503.15 ETO16952.1 - 2.9e-33 115.1 10.0 2.9e-33 115.1 6.9 3.8 3 1 0 3 3 3 1 G-protein alpha subunit Ribosomal_L50 PF10501.4 ETO16953.1 - 0.032 14.2 0.4 0.11 12.4 0.3 1.9 1 0 0 1 1 1 0 Ribosomal subunit 39S RabGAP-TBC PF00566.13 ETO16954.1 - 1.5e-25 89.9 4.9 3.8e-25 88.6 3.4 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Ank_2 PF12796.2 ETO16955.1 - 1.1e-25 89.7 0.0 7.1e-13 48.7 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETO16955.1 - 5.3e-18 63.8 0.1 1.6e-07 30.8 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 ETO16955.1 - 7e-14 50.5 0.0 9.8e-06 25.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 ETO16955.1 - 6.3e-13 48.5 0.0 3.9e-06 26.9 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO16955.1 - 5.7e-11 42.6 0.3 1.6e-10 41.1 0.0 1.9 2 1 1 3 3 3 1 Ankyrin repeats (many copies) UPF0054 PF02130.12 ETO16955.1 - 0.061 12.6 0.1 0.13 11.5 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein family UPF0054 Ank_2 PF12796.2 ETO16956.1 - 8.3e-09 35.6 0.0 0.0033 17.7 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETO16956.1 - 8.9e-09 34.7 0.1 0.0059 16.3 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 ETO16956.1 - 4.2e-07 30.0 0.0 0.011 16.0 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO16956.1 - 9.8e-07 28.4 0.1 0.0096 16.0 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 ETO16956.1 - 0.00047 20.5 0.0 0.65 10.5 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PT PF04886.7 ETO16957.1 - 1.1e-14 53.3 155.2 0.00047 19.4 15.9 7.8 3 2 4 7 7 7 6 PT repeat VWA_2 PF13519.1 ETO16957.1 - 7.6e-09 35.9 0.0 0.0025 17.9 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA PF00092.23 ETO16957.1 - 5e-07 29.5 1.7 0.011 15.4 0.1 3.1 2 1 0 2 2 2 2 von Willebrand factor type A domain Gloverin PF10793.4 ETO16957.1 - 0.12 11.9 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Gloverin-like protein DUF2206 PF09971.4 ETO16958.1 - 0.1 11.3 5.9 0.14 10.8 4.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) PBP1_TM PF14812.1 ETO16959.1 - 0.13 12.5 7.3 0.36 11.1 5.1 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.4 ETO16959.1 - 0.46 9.1 13.4 0.74 8.4 9.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 ETO16959.1 - 0.54 9.7 5.9 0.97 8.9 4.1 1.4 1 0 0 1 1 1 0 Nucleoplasmin Cwf_Cwc_15 PF04889.7 ETO16959.1 - 0.73 9.4 9.3 0.025 14.2 2.2 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Myco_arth_vir_N PF09610.5 ETO16960.1 - 0.1 12.5 0.2 0.31 11.0 0.2 1.8 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Gly_kinase PF02595.10 ETO16961.1 - 3.4e-83 279.4 0.0 1.2e-82 277.6 0.0 1.8 1 1 0 1 1 1 1 Glycerate kinase family ADH_zinc_N PF00107.21 ETO16961.1 - 0.029 13.9 0.3 3 7.4 0.0 2.8 2 1 1 3 3 3 0 Zinc-binding dehydrogenase zf-RVT PF13966.1 ETO16962.1 - 1.3e-05 25.3 0.3 2e-05 24.7 0.2 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase WD40 PF00400.27 ETO16963.1 - 4.6e-66 216.5 29.1 3e-12 45.8 0.3 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO16963.1 - 2.1e-09 36.1 12.8 0.077 11.1 0.5 5.9 2 1 4 6 6 6 6 Nucleoporin Nup120/160 Peptidase_C14 PF00656.17 ETO16964.1 - 1e-08 35.1 0.3 1.3e-08 34.9 0.2 1.1 1 0 0 1 1 1 1 Caspase domain Caleosin PF05042.8 ETO16964.1 - 0.019 14.5 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Caleosin related protein Borrelia_orfA PF02414.10 ETO16964.1 - 0.052 12.6 1.3 0.06 12.4 0.9 1.3 1 1 0 1 1 1 0 Borrelia ORF-A UL11 PF11094.3 ETO16964.1 - 0.086 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Membrane-associated tegument protein RVT_1 PF00078.22 ETO16965.1 - 6.2e-09 35.5 0.2 8.3e-09 35.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.27 ETO16966.1 - 2.4e-163 524.9 56.2 1.5e-11 43.6 0.2 16.3 16 0 0 16 16 16 16 WD domain, G-beta repeat Nup160 PF11715.3 ETO16966.1 - 2.1e-15 55.9 28.8 0.051 11.6 0.3 12.6 2 2 11 13 13 13 10 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO16966.1 - 6.1e-08 32.4 1.7 0.016 14.7 0.0 3.7 2 2 1 3 3 3 3 PQQ-like domain PD40 PF07676.7 ETO16966.1 - 5.2e-07 29.1 12.1 6.7 6.4 0.0 8.2 8 0 0 8 8 8 2 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 ETO16966.1 - 4.3e-06 25.9 8.3 2.1 7.3 0.0 7.1 5 3 3 9 9 9 3 Protein of unknown function (DUF1258) Pentapeptide PF00805.17 ETO16966.1 - 1e-05 24.6 0.7 2.1e-05 23.6 0.5 1.4 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Mid2 PF04478.7 ETO16966.1 - 2.6e-05 23.6 17.0 6.8 6.0 0.0 7.8 5 4 2 8 8 8 3 Mid2 like cell wall stress sensor Pentapeptide_4 PF13599.1 ETO16966.1 - 5.1e-05 23.0 0.4 0.00012 21.7 0.3 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) DUF1938 PF09153.5 ETO16966.1 - 0.00015 21.5 2.7 2.1 8.1 0.1 5.3 4 2 1 5 5 5 2 Domain of unknown function (DUF1938) Pentapeptide_3 PF13576.1 ETO16966.1 - 0.00061 19.6 1.1 0.0019 18.0 0.7 1.9 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) DENN PF02141.16 ETO16968.1 - 1e-30 106.8 1.4 1.6e-30 106.1 0.9 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain Ras PF00071.17 ETO16969.1 - 6.6e-07 28.8 0.0 1.4e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO16969.1 - 0.00048 20.6 0.0 0.001 19.5 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 ETO16969.1 - 0.035 14.0 1.2 0.3 11.0 0.8 2.1 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.4 ETO16969.1 - 0.06 12.8 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PapD_C PF02753.12 ETO16971.1 - 0.018 14.8 0.2 0.044 13.6 0.1 1.6 1 0 0 1 1 1 0 Pili assembly chaperone PapD, C-terminal domain CD36 PF01130.16 ETO16973.1 - 1.6e-12 46.5 0.3 1.9e-12 46.2 0.2 1.1 1 0 0 1 1 1 1 CD36 family IBB PF01749.15 ETO16974.1 - 5.3e-06 26.5 4.5 5.3e-06 26.5 3.1 2.0 2 0 0 2 2 2 1 Importin beta binding domain Arm PF00514.18 ETO16974.1 - 0.0046 16.7 0.1 0.26 11.1 0.1 2.8 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat Mis12 PF05859.7 ETO16974.1 - 0.033 13.9 0.8 0.092 12.5 0.5 1.7 1 0 0 1 1 1 0 Mis12 protein RICTOR_V PF14668.1 ETO16974.1 - 0.042 13.7 0.0 12 5.9 0.0 2.8 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 Arm PF00514.18 ETO16975.1 - 1.3e-08 34.2 0.1 0.015 15.1 0.0 3.7 3 1 1 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 ETO16975.1 - 0.0056 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 HEAT repeats Peptidase_C11 PF03415.9 ETO16975.1 - 0.023 13.7 0.1 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Clostripain family HEAT_EZ PF13513.1 ETO16975.1 - 0.037 14.5 0.0 1.5 9.3 0.0 2.5 1 1 1 2 2 2 0 HEAT-like repeat Rhabdo_ncap PF00945.13 ETO16975.1 - 0.073 11.6 0.1 0.098 11.2 0.1 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Microtub_bind PF13931.1 ETO16976.1 - 2.9e-06 27.4 1.2 2.9e-06 27.4 0.8 2.9 3 1 1 4 4 4 1 Kinesin-associated microtubule-binding Nop16 PF09420.5 ETO16976.1 - 0.0087 16.1 2.1 0.023 14.8 1.4 1.7 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 DUF2229 PF09989.4 ETO16976.1 - 0.28 10.6 0.1 0.28 10.6 0.0 2.3 2 1 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) RuBisCO_small PF00101.15 ETO16976.1 - 0.4 10.5 3.4 0.63 9.9 0.2 2.5 1 1 2 3 3 3 0 Ribulose bisphosphate carboxylase, small chain DSPc PF00782.15 ETO16976.1 - 1.8 8.1 5.4 3 7.4 0.6 2.6 2 1 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Kinesin PF00225.18 ETO16977.1 - 5.4e-88 294.9 1.5 1.3e-87 293.6 1.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain AAA_10 PF12846.2 ETO16977.1 - 0.046 13.1 1.9 2.2 7.6 0.7 2.3 2 0 0 2 2 2 0 AAA-like domain BCDHK_Adom3 PF10436.4 ETO16978.1 - 3.8e-27 94.8 0.0 1.5e-14 53.8 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 ETO16978.1 - 2e-13 50.0 0.0 3.2e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 ETO16978.1 - 2.8e-05 23.8 0.0 5.5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase rRNA_processing PF08524.6 ETO16979.1 - 0.0084 15.9 29.3 0.012 15.4 20.3 1.1 1 0 0 1 1 1 1 rRNA processing Macoilin PF09726.4 ETO16979.1 - 0.013 13.8 15.3 0.014 13.7 10.6 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF1777 PF08648.7 ETO16979.1 - 0.031 14.0 22.9 0.039 13.6 15.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DUF572 PF04502.8 ETO16979.1 - 0.063 12.4 23.6 0.072 12.2 16.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) SET PF00856.23 ETO16979.1 - 0.071 13.4 4.3 0.086 13.1 3.0 1.1 1 0 0 1 1 1 0 SET domain NARP1 PF12569.3 ETO16979.1 - 0.083 11.6 18.0 0.094 11.4 12.5 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FAM60A PF15396.1 ETO16979.1 - 0.15 11.7 18.1 0.2 11.3 12.6 1.2 1 0 0 1 1 1 0 Protein Family FAM60A SAPS PF04499.10 ETO16979.1 - 0.17 10.4 11.0 0.18 10.3 7.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Paramyxo_ncap PF00973.14 ETO16979.1 - 0.2 10.3 13.4 0.22 10.1 9.3 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Pex16 PF08610.5 ETO16979.1 - 0.24 10.3 5.8 0.27 10.1 4.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF3807 PF12720.2 ETO16979.1 - 0.54 10.3 23.7 0.82 9.8 16.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) YL1 PF05764.8 ETO16979.1 - 0.61 9.6 33.4 0.78 9.2 23.2 1.1 1 0 0 1 1 1 0 YL1 nuclear protein AUX_IAA PF02309.11 ETO16979.1 - 0.72 9.5 17.6 0.86 9.3 12.2 1.1 1 0 0 1 1 1 0 AUX/IAA family NPR3 PF03666.8 ETO16979.1 - 0.72 8.3 21.6 0.93 7.9 15.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MIP-T3 PF10243.4 ETO16979.1 - 0.99 7.7 37.3 1.2 7.5 25.8 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1510 PF07423.6 ETO16979.1 - 1.1 8.5 29.0 1.5 8.1 20.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF3513 PF12026.3 ETO16979.1 - 1.3 8.5 14.3 1.7 8.1 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) Ndc1_Nup PF09531.5 ETO16979.1 - 1.7 6.9 13.8 2 6.7 9.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MDFI PF15316.1 ETO16979.1 - 1.8 8.5 10.1 2.5 8.0 7.0 1.3 1 0 0 1 1 1 0 MyoD family inhibitor DUF4613 PF15390.1 ETO16979.1 - 2.4 6.2 13.1 2.8 5.9 9.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) SprA-related PF12118.3 ETO16979.1 - 3.1 7.0 22.9 3.8 6.7 15.9 1.1 1 0 0 1 1 1 0 SprA-related family Pex14_N PF04695.8 ETO16979.1 - 3.9 7.5 16.0 0.16 12.0 4.3 2.1 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DDRGK PF09756.4 ETO16979.1 - 4.1 6.7 27.3 5.8 6.2 18.9 1.3 1 0 0 1 1 1 0 DDRGK domain DUF4544 PF15077.1 ETO16979.1 - 5.3 6.4 16.7 6.5 6.1 11.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) CDC45 PF02724.9 ETO16979.1 - 6.7 4.6 22.0 8.5 4.2 15.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Mem_trans PF03547.13 ETO16979.1 - 6.8 4.8 11.8 8.3 4.5 8.2 1.1 1 0 0 1 1 1 0 Membrane transport protein FLO_LFY PF01698.11 ETO16979.1 - 6.9 5.4 19.4 9.5 4.9 13.4 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein U79_P34 PF03064.11 ETO16979.1 - 6.9 6.1 26.6 8.5 5.8 18.4 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Transformer PF06495.6 ETO16979.1 - 8.3 6.2 15.4 12 5.7 10.7 1.3 1 0 0 1 1 1 0 Fruit fly transformer protein Ycf1 PF05758.7 ETO16979.1 - 9.4 3.8 20.2 11 3.5 14.0 1.0 1 0 0 1 1 1 0 Ycf1 DUF4551 PF15087.1 ETO16979.1 - 9.5 4.4 15.7 11 4.2 10.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Auxin_repressed PF05564.7 ETO16981.1 - 0.012 16.2 2.1 0.016 15.8 1.4 1.3 1 0 0 1 1 1 0 Dormancy/auxin associated protein RabGAP-TBC PF00566.13 ETO16982.1 - 6.4e-07 29.0 0.8 1.1e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain CDC45 PF02724.9 ETO16983.1 - 1.6e-05 23.2 1.7 1.6e-05 23.2 1.2 1.1 1 0 0 1 1 1 1 CDC45-like protein Osteopontin PF00865.13 ETO16983.1 - 0.00012 21.4 20.7 0.00012 21.4 14.3 1.3 2 0 0 2 2 2 1 Osteopontin Astro_capsid PF03115.9 ETO16983.1 - 0.061 11.5 6.8 0.074 11.3 4.7 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Secretin_N_2 PF07655.8 ETO16983.1 - 0.23 11.8 16.6 0.54 10.6 11.5 1.7 1 0 0 1 1 1 0 Secretin N-terminal domain Daxx PF03344.10 ETO16983.1 - 0.72 8.2 17.9 0.9 7.9 12.4 1.1 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 ETO16983.1 - 1.4 7.5 24.1 2 7.0 16.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 ETO16983.1 - 4 5.2 17.4 5 4.9 12.0 1.1 1 0 0 1 1 1 0 Nop14-like family Atx10homo_assoc PF09759.4 ETO16984.1 - 8.3e-05 22.2 3.7 0.78 9.5 0.1 4.9 4 0 0 4 4 4 2 Spinocerebellar ataxia type 10 protein domain Ric8 PF10165.4 ETO16984.1 - 0.00038 19.3 0.3 0.83 8.4 0.0 3.3 2 2 0 2 2 2 2 Guanine nucleotide exchange factor synembryn Arm PF00514.18 ETO16984.1 - 0.0014 18.3 9.7 2.8 7.9 0.0 7.2 7 1 1 8 8 8 2 Armadillo/beta-catenin-like repeat WW PF00397.21 ETO16985.1 - 0.0013 18.5 0.3 0.0029 17.4 0.2 1.6 1 0 0 1 1 1 1 WW domain zf-RanBP PF00641.13 ETO16985.1 - 0.0047 15.9 5.4 0.0091 15.0 3.7 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RNA_POL_M_15KD PF02150.11 ETO16985.1 - 0.012 15.2 0.2 0.012 15.2 0.1 2.4 1 1 1 2 2 2 0 RNA polymerases M/15 Kd subunit DZR PF12773.2 ETO16985.1 - 0.034 13.9 1.4 0.07 12.9 1.0 1.5 1 0 0 1 1 1 0 Double zinc ribbon DUF4551 PF15087.1 ETO16985.1 - 0.21 9.8 4.5 0.25 9.6 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Basic PF01586.11 ETO16985.1 - 0.23 12.1 4.5 0.28 11.9 0.4 2.3 1 1 1 2 2 2 0 Myogenic Basic domain Ebola_NP PF05505.7 ETO16985.1 - 0.29 9.1 9.9 0.31 9.0 6.9 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Astro_capsid PF03115.9 ETO16985.1 - 0.71 8.0 8.2 0.74 7.9 5.7 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor ADK PF00406.17 ETO16986.1 - 3.7e-36 124.2 0.0 4.9e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 ETO16986.1 - 2.7e-11 44.3 0.0 4.1e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.9 ETO16986.1 - 3.2e-10 39.4 2.7 7e-10 38.4 1.9 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 ETO16986.1 - 6.6e-08 32.9 0.0 1.6e-07 31.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETO16986.1 - 8.9e-07 28.8 0.0 1.7e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 ETO16986.1 - 0.00078 18.5 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 ETO16986.1 - 0.0019 17.3 0.0 0.0036 16.4 0.0 1.4 1 1 0 1 1 1 1 Zeta toxin IstB_IS21 PF01695.12 ETO16986.1 - 0.017 14.5 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein GFA PF04828.9 ETO16986.1 - 0.028 14.3 0.2 0.48 10.4 0.0 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme A2L_zn_ribbon PF08792.5 ETO16986.1 - 0.036 13.5 0.7 1.6 8.3 0.0 2.5 2 0 0 2 2 2 0 A2L zinc ribbon domain HNH_5 PF14279.1 ETO16986.1 - 0.18 11.8 1.5 2.4 8.2 1.0 2.4 1 1 0 1 1 1 0 HNH endonuclease WD40 PF00400.27 ETO16987.1 - 5.5e-38 127.5 11.3 6.6e-10 38.4 0.0 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 ETO16987.1 - 1.5e-12 47.6 0.1 2.6e-05 23.9 0.0 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 ETO16987.1 - 3.6e-08 32.6 0.4 7.6e-08 31.5 0.1 1.6 1 1 1 2 2 2 1 Coatomer WD associated region PD40 PF07676.7 ETO16987.1 - 7.8e-07 28.6 7.1 0.32 10.7 0.1 5.7 6 0 0 6 6 6 3 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO16987.1 - 1.1e-05 23.8 0.2 0.2 9.7 0.0 3.1 1 1 1 3 3 3 3 Nucleoporin Nup120/160 DPPIV_N PF00930.16 ETO16987.1 - 0.0001 21.0 0.2 1.2 7.6 0.0 4.2 2 1 1 4 4 4 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nucleoporin_N PF08801.6 ETO16987.1 - 0.0083 14.9 2.2 0.02 13.6 1.6 2.0 1 1 0 1 1 1 1 Nup133 N terminal like PQQ_2 PF13360.1 ETO16987.1 - 0.028 13.8 0.0 0.083 12.3 0.0 1.8 1 1 0 1 1 1 0 PQQ-like domain DUF2963 PF11178.3 ETO16987.1 - 0.29 10.5 9.5 11 5.4 0.2 5.2 4 2 3 7 7 7 0 Protein of unknown function (DUF2963) Proteasome_A_N PF10584.4 ETO16987.1 - 0.75 9.1 12.0 17 4.8 0.2 4.6 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature DUF2057 PF09829.4 ETO16988.1 - 0.0029 17.2 0.0 0.0091 15.6 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2057) DUF3901 PF13040.1 ETO16988.1 - 0.69 9.2 6.6 0.26 10.5 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3901) IFT43 PF15305.1 ETO16988.1 - 5.4 7.0 11.1 0.23 11.4 0.3 2.6 2 0 0 2 2 2 0 Intraflagellar transport protein 43 DUF2681 PF10883.3 ETO16989.1 - 0.0057 16.8 5.1 0.0057 16.8 3.5 2.9 2 2 1 3 3 3 1 Protein of unknown function (DUF2681) Rsc14 PF08586.5 ETO16989.1 - 0.091 13.2 1.7 0.12 12.8 0.2 1.9 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit NICE-3 PF07406.6 ETO16989.1 - 0.83 9.1 6.0 0.13 11.7 0.4 2.1 2 0 0 2 2 2 0 NICE-3 protein Med11 PF10280.4 ETO16989.1 - 1.5 8.8 13.0 0.6 10.1 3.9 2.8 2 1 0 2 2 2 0 Mediator complex protein FAD-SLDH PF12318.3 ETO16989.1 - 3.8 7.1 7.5 4 7.0 0.0 3.1 2 1 1 3 3 3 0 Membrane bound FAD containing D-sorbitol dehydrogenase Kelch_6 PF13964.1 ETO16990.1 - 4.3e-09 36.1 0.8 0.001 19.1 0.1 4.1 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETO16990.1 - 3.5e-05 23.4 1.7 0.045 13.5 0.0 3.9 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO16990.1 - 0.0001 22.1 1.9 0.053 13.4 0.1 4.2 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 ETO16990.1 - 0.00042 19.8 7.1 0.17 11.4 0.1 4.1 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO16990.1 - 0.00099 18.7 5.2 0.041 13.6 0.0 4.5 6 1 0 6 6 6 1 Kelch motif Kelch_3 PF13415.1 ETO16990.1 - 0.014 15.5 0.2 28 5.0 0.1 3.7 3 0 0 3 3 3 0 Galactose oxidase, central domain WD40 PF00400.27 ETO16991.1 - 1.9e-68 224.1 5.1 5.1e-11 42.0 0.0 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO16991.1 - 7.2e-08 31.1 0.6 0.0033 15.7 0.0 3.5 1 1 3 4 4 4 3 Cytochrome D1 heme domain PD40 PF07676.7 ETO16991.1 - 3.1e-06 26.7 8.6 3.2 7.5 0.0 6.9 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO16991.1 - 0.00036 20.0 0.0 0.023 14.1 0.0 2.6 1 1 1 2 2 2 2 PQQ-like domain Str_synth PF03088.11 ETO16991.1 - 0.0024 17.8 0.1 0.14 12.1 0.0 3.5 3 1 0 3 3 3 1 Strictosidine synthase Nbas_N PF15492.1 ETO16991.1 - 0.0088 15.1 0.6 4 6.4 0.1 4.2 1 1 3 5 5 5 1 Neuroblastoma-amplified sequence, N terminal BBS2_Mid PF14783.1 ETO16991.1 - 0.025 14.3 4.8 0.11 12.2 0.5 3.8 2 2 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Resistin PF06954.6 ETO16991.1 - 0.062 13.5 0.1 1.3 9.3 0.0 3.0 2 1 1 3 3 3 0 Resistin Methyltransf_3 PF01596.12 ETO16991.1 - 0.075 12.0 0.1 5.7 5.9 0.0 3.2 3 1 1 4 4 4 0 O-methyltransferase Proteasome_A_N PF10584.4 ETO16991.1 - 0.62 9.4 9.6 50 3.3 0.0 5.2 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 ETO16992.1 - 2.8e-57 188.6 22.1 1.8e-12 46.5 1.3 6.2 6 1 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO16992.1 - 1.2e-05 23.6 6.4 0.93 7.5 0.1 4.1 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO16992.1 - 0.00024 19.9 12.4 0.12 11.1 0.3 3.9 1 1 1 3 3 3 3 Nup133 N terminal like USP7_C2 PF14533.1 ETO16992.1 - 0.038 13.4 1.3 7.3 5.9 0.0 3.3 1 1 1 3 3 3 0 Ubiquitin-specific protease C-terminal Acyltransferase PF01553.16 ETO16994.1 - 3.6e-14 52.3 0.0 5.7e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase EF-hand_1 PF00036.27 ETO16994.1 - 4.7e-06 25.5 0.3 1.1e-05 24.3 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 ETO16994.1 - 6.5e-05 22.0 0.2 0.00021 20.4 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 ETO16994.1 - 0.00042 19.8 0.3 0.00099 18.6 0.2 1.8 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 ETO16994.1 - 0.00043 20.3 0.0 0.00071 19.6 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO16994.1 - 0.0018 17.9 0.3 0.0048 16.6 0.2 1.8 1 0 0 1 1 1 1 EF-hand domain Cullin_Nedd8 PF10557.4 ETO16995.1 - 0.41 10.5 6.2 4.5 7.1 0.0 3.3 3 1 0 3 3 3 0 Cullin protein neddylation domain EF-hand_7 PF13499.1 ETO16996.1 - 2.5e-06 27.5 0.2 0.0051 16.9 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO16996.1 - 5.4e-06 25.8 0.4 0.004 16.9 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 ETO16996.1 - 5.6e-06 25.2 0.4 0.00089 18.3 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 ETO16996.1 - 0.0003 19.9 0.4 0.0022 17.2 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 ETO16996.1 - 0.00082 18.9 0.1 0.0082 15.7 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair Nucleoplasmin PF03066.10 ETO16997.1 - 4.4 6.8 18.0 1.4 8.4 6.1 2.6 2 0 0 2 2 2 0 Nucleoplasmin GAGA_bind PF06217.7 ETO16998.1 - 0.098 12.6 4.6 0.13 12.2 3.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family PcfK PF14058.1 ETO16998.1 - 2.4 8.2 15.0 1.6e+02 2.4 10.4 2.3 1 1 0 1 1 1 0 PcfK-like protein zf-C4H2 PF10146.4 ETO16999.1 - 0.24 11.3 4.2 0.46 10.4 0.1 1.8 1 1 1 2 2 2 0 Zinc finger-containing protein DUF342 PF03961.8 ETO16999.1 - 0.36 9.2 3.9 0.48 8.7 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Bap31 PF05529.7 ETO16999.1 - 1.5 8.2 10.2 1.3 8.4 6.4 1.3 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like Atg14 PF10186.4 ETO16999.1 - 2.3 7.0 9.3 4.2 6.2 6.5 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FliD_N PF02465.13 ETO16999.1 - 6.2 7.2 8.0 1.1 9.6 3.0 1.7 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus ABC_tran PF00005.22 ETO17002.1 - 2.9e-08 34.1 1.8 2.1e-07 31.3 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 ETO17002.1 - 0.017 15.1 0.1 0.03 14.3 0.0 1.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 ETO17002.1 - 0.04 13.4 0.2 0.074 12.5 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 ETO17002.1 - 0.12 12.7 0.7 0.12 12.7 0.5 2.2 1 1 0 2 2 2 0 AAA domain AAA_15 PF13175.1 ETO17002.1 - 0.23 10.4 3.7 0.058 12.4 0.2 1.6 1 1 0 2 2 2 0 AAA ATPase domain Secretin_N_2 PF07655.8 ETO17003.1 - 1.7 9.0 12.9 3.4 8.1 8.9 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain DnaJ_CXXCXGXG PF00684.14 ETO17004.1 - 1.2e-15 57.2 18.8 2.2e-15 56.4 13.1 1.4 1 0 0 1 1 1 1 DnaJ central domain A2L_zn_ribbon PF08792.5 ETO17004.1 - 0.25 10.8 0.2 0.25 10.8 0.1 3.7 3 1 1 4 4 4 0 A2L zinc ribbon domain PAAR_motif PF05488.8 ETO17004.1 - 0.36 10.8 3.4 2.9 7.9 0.2 2.2 1 1 1 2 2 2 0 PAAR motif HypA PF01155.14 ETO17004.1 - 5.4 6.7 13.4 0.8 9.4 2.2 2.1 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family CTDII PF01556.13 ETO17005.1 - 3.2e-18 65.3 0.1 9.2e-18 63.9 0.0 1.8 2 0 0 2 2 2 1 DnaJ C terminal domain PAP_central PF04928.12 ETO17007.1 - 0.082 11.7 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Poly(A) polymerase central domain YonK PF09642.5 ETO17008.1 - 0.078 12.6 0.2 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 YonK protein MIP-T3 PF10243.4 ETO17009.1 - 0.00028 19.5 55.5 0.00034 19.2 38.4 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 PAT1 PF09770.4 ETO17009.1 - 0.34 9.1 33.6 0.46 8.6 23.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC27 PF09507.5 ETO17009.1 - 0.43 9.7 53.8 0.77 8.9 37.3 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Daxx PF03344.10 ETO17009.1 - 0.62 8.4 27.8 0.77 8.1 19.2 1.0 1 0 0 1 1 1 0 Daxx Family Mob1_phocein PF03637.12 ETO17010.1 - 2.5e-38 131.4 0.0 3.2e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family DUF342 PF03961.8 ETO17011.1 - 0.0013 17.2 4.5 0.0013 17.2 3.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF342) DUF3584 PF12128.3 ETO17011.1 - 0.0026 15.2 4.6 0.0028 15.1 3.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF745 PF05335.8 ETO17011.1 - 0.008 15.7 3.6 0.01 15.3 2.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF745) DUF87 PF01935.12 ETO17011.1 - 0.011 15.5 1.3 0.016 15.0 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF87 UvrD_C PF13361.1 ETO17011.1 - 0.015 14.7 3.3 0.017 14.5 2.3 1.1 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF4407 PF14362.1 ETO17011.1 - 0.016 14.1 4.0 0.021 13.7 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CorA PF01544.13 ETO17011.1 - 0.018 14.1 1.3 0.025 13.6 0.9 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein HR1 PF02185.11 ETO17011.1 - 0.25 11.0 7.8 0.52 10.0 3.6 2.2 2 0 0 2 2 2 0 Hr1 repeat DUF1311 PF07007.7 ETO17011.1 - 0.27 11.3 4.6 0.34 11.0 2.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1311) PRD PF00874.15 ETO17011.1 - 0.42 10.7 4.3 0.63 10.1 0.9 2.1 1 1 1 2 2 2 0 PRD domain Sds3 PF08598.6 ETO17011.1 - 0.44 10.0 9.5 1.1 8.6 6.6 1.6 1 1 0 1 1 1 0 Sds3-like DUF725 PF05267.7 ETO17011.1 - 0.48 10.3 6.2 0.38 10.6 1.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF725) YlqD PF11068.3 ETO17011.1 - 0.72 9.8 6.3 0.95 9.4 4.4 1.3 1 0 0 1 1 1 0 YlqD protein V_ATPase_I PF01496.14 ETO17011.1 - 0.89 7.3 3.8 1 7.1 2.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.7 ETO17011.1 - 2.1 8.1 5.3 3.8 7.3 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) OmpH PF03938.9 ETO17011.1 - 6.2 6.7 9.8 11 5.9 6.8 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) IncA PF04156.9 ETO17011.1 - 10 5.6 8.9 12 5.3 6.2 1.1 1 0 0 1 1 1 0 IncA protein uDENN PF03456.13 ETO17012.1 - 2.3e-10 40.2 0.1 4e-08 33.1 0.0 2.5 2 0 0 2 2 2 2 uDENN domain SRP54 PF00448.17 ETO17012.1 - 0.0027 17.1 0.0 0.0045 16.4 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain ArfGap PF01412.13 ETO17012.1 - 0.031 14.0 1.3 0.031 14.0 0.9 1.6 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Ras PF00071.17 ETO17014.1 - 2.3e-19 69.3 0.0 3.2e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO17014.1 - 0.0013 19.1 0.0 0.0023 18.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein DLIC PF05783.6 ETO17014.1 - 0.0028 16.4 0.0 0.0047 15.6 0.0 1.3 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) Arf PF00025.16 ETO17014.1 - 0.0071 15.6 0.0 0.023 13.9 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO17014.1 - 0.085 12.2 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain PEPCK_ATP PF01293.15 ETO17014.1 - 0.094 11.2 0.0 0.19 10.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase UCH PF00443.24 ETO17015.1 - 6.2e-13 48.4 0.3 1.4e-12 47.3 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Gtr1_RagA PF04670.7 ETO17015.1 - 0.25 10.4 3.6 0.66 9.0 2.5 1.9 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region UCH PF00443.24 ETO17016.1 - 1.4e-06 27.6 11.7 8.1e-06 25.1 8.1 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO17016.1 - 0.47 9.8 10.1 3 7.2 7.0 2.6 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 ETO17017.1 - 4.7e-72 235.5 10.6 3.2e-14 52.1 0.1 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO17017.1 - 1.2e-12 47.9 0.0 3.5e-08 33.4 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO17017.1 - 1.7e-07 29.8 0.0 0.0093 14.3 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.3 ETO17017.1 - 3.5e-06 25.4 3.8 0.13 10.3 0.2 4.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO17017.1 - 5.2e-05 22.1 2.9 4.2 6.0 0.0 4.7 2 2 3 5 5 5 1 Nup133 N terminal like Proteasome_A_N PF10584.4 ETO17017.1 - 0.00017 20.8 4.1 3.3 7.1 0.0 4.8 5 0 0 5 5 5 2 Proteasome subunit A N-terminal signature SGL PF08450.7 ETO17017.1 - 0.00074 18.9 0.0 0.44 9.8 0.0 2.3 1 1 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Resistin PF06954.6 ETO17017.1 - 0.0014 18.9 0.7 51 4.2 0.0 4.6 2 2 3 5 5 5 0 Resistin DUF1258 PF06869.7 ETO17017.1 - 0.0019 17.3 1.0 1.3 8.0 0.1 3.5 2 2 2 4 4 4 1 Protein of unknown function (DUF1258) PD40 PF07676.7 ETO17017.1 - 0.002 17.7 6.5 0.82 9.4 0.0 4.4 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat SusE PF14292.1 ETO17017.1 - 0.039 13.7 0.1 4.6 7.0 0.0 3.5 5 0 0 5 5 5 0 SusE outer membrane protein PQQ_2 PF13360.1 ETO17017.1 - 0.067 12.6 0.1 6.3 6.1 0.0 2.2 1 1 0 2 2 2 0 PQQ-like domain DPPIV_N PF00930.16 ETO17017.1 - 0.12 10.9 0.0 15 3.9 0.0 3.2 1 1 4 5 5 5 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PLD_C PF12357.3 ETO17017.1 - 0.16 11.4 0.4 68 3.1 0.0 3.9 3 1 0 4 4 4 0 Phospholipase D C terminal UCH PF00443.24 ETO17018.1 - 2.2e-22 79.4 0.6 1.4e-21 76.8 0.1 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO17018.1 - 3.6e-08 33.1 2.3 3.6e-08 33.1 1.6 2.8 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase DUF3671 PF12420.3 ETO17019.1 - 0.0061 16.5 0.6 0.0061 16.5 0.5 2.3 2 0 0 2 2 2 1 Protein of unknown function IBR PF01485.16 ETO17020.1 - 0.0016 18.2 11.2 0.0016 18.2 7.8 2.4 2 2 1 3 3 3 1 IBR domain TniQ PF06527.6 ETO17020.1 - 0.12 12.6 4.9 0.88 9.7 0.2 2.6 2 1 0 2 2 2 0 TniQ UQ_con PF00179.21 ETO17022.1 - 0.00027 20.3 0.1 0.00077 18.9 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SLX9 PF15341.1 ETO17022.1 - 2.2 8.7 14.7 4.5 7.7 6.2 2.4 2 1 0 2 2 2 0 Ribosome biogenesis protein SLX9 DUF3262 PF11660.3 ETO17023.1 - 0.4 10.8 4.4 0.29 11.2 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3262) NfeD PF01957.13 ETO17023.1 - 2.2 8.4 6.6 0.94 9.6 1.5 2.3 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding Hid1 PF12722.2 ETO17024.1 - 2.4 5.7 7.7 2.7 5.5 5.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AMPKBI PF04739.10 ETO17024.1 - 5.1 7.0 6.6 19 5.1 0.1 2.3 2 0 0 2 2 2 0 5'-AMP-activated protein kinase beta subunit, interation domain DUF1765 PF08578.5 ETO17025.1 - 8.3e-11 42.0 0.4 8.3e-11 42.0 0.3 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) RGS PF00615.14 ETO17026.1 - 9.3e-05 22.5 0.7 0.0012 18.8 0.5 2.3 1 1 0 1 1 1 1 Regulator of G protein signaling domain Kinesin PF00225.18 ETO17027.1 - 5.7e-10 38.4 0.3 1e-09 37.5 0.2 1.4 1 0 0 1 1 1 1 Kinesin motor domain V-set PF07686.12 ETO17028.1 - 0.018 14.8 0.8 0.018 14.8 0.5 1.9 2 1 0 2 2 2 0 Immunoglobulin V-set domain PIP5K PF01504.13 ETO17029.1 - 1.4e-29 102.9 0.0 2.2e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Nro1 PF12753.2 ETO17029.1 - 0.062 12.2 0.2 0.086 11.7 0.1 1.4 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 MARVEL PF01284.18 ETO17030.1 - 0.053 13.3 3.8 0.08 12.7 2.6 1.3 1 0 0 1 1 1 0 Membrane-associating domain RGS PF00615.14 ETO17031.1 - 6.8e-10 39.0 0.6 1.5e-09 37.9 0.4 1.6 1 1 0 1 1 1 1 Regulator of G protein signaling domain FWWh PF14922.1 ETO17031.1 - 0.04 13.4 0.4 0.079 12.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF3789 PF12664.2 ETO17032.1 - 3.3 7.0 7.5 6 6.2 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) Actin PF00022.14 ETO17033.1 - 1.7e-12 46.5 0.0 1.8e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Actin zf-CCHC PF00098.18 ETO17035.1 - 0.0029 17.4 1.2 0.0059 16.4 0.8 1.5 1 0 0 1 1 1 1 Zinc knuckle Flag1_repress PF03614.8 ETO17035.1 - 0.034 13.7 2.6 0.051 13.1 1.8 1.3 1 0 0 1 1 1 0 Repressor of phase-1 flagellin GLE1 PF07817.8 ETO17035.1 - 0.049 12.5 3.0 0.076 11.9 2.1 1.3 1 0 0 1 1 1 0 GLE1-like protein zf-CCHC_3 PF13917.1 ETO17035.1 - 0.081 12.6 2.0 0.18 11.5 1.4 1.6 1 0 0 1 1 1 0 Zinc knuckle Abhydrolase_6 PF12697.2 ETO17036.1 - 0.16 11.8 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Kelch_1 PF01344.20 ETO17038.1 - 0.014 14.8 0.7 0.76 9.3 0.1 3.1 3 0 0 3 3 3 0 Kelch motif IZUMO PF15005.1 ETO17038.1 - 0.031 14.3 2.4 1.4 8.9 0.6 2.3 2 0 0 2 2 2 0 Izumo sperm-egg fusion DUF641 PF04859.7 ETO17039.1 - 0.012 15.3 1.0 0.012 15.3 0.7 2.8 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) IncA PF04156.9 ETO17039.1 - 0.026 14.1 19.0 0.081 12.5 13.2 1.7 1 1 0 1 1 1 0 IncA protein Reo_sigmaC PF04582.7 ETO17039.1 - 0.083 12.0 6.0 0.23 10.5 4.2 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 ETO17039.1 - 0.16 10.3 18.6 0.24 9.8 12.9 1.3 1 0 0 1 1 1 0 AAA domain CmcH_NodU PF02543.10 ETO17039.1 - 0.19 10.8 8.9 0.2 10.7 6.2 1.1 1 0 0 1 1 1 0 Carbamoyltransferase EURL PF06937.6 ETO17039.1 - 0.75 9.1 14.3 1.4 8.3 0.2 2.0 1 1 1 2 2 2 0 EURL protein Lzipper-MIP1 PF14389.1 ETO17039.1 - 0.8 9.8 12.0 7.2 6.7 0.5 2.7 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 GAS PF13851.1 ETO17039.1 - 0.98 8.5 26.3 2.6 7.2 15.1 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.4 ETO17039.1 - 1.1 9.2 19.0 2.5 8.0 7.5 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF755 PF05501.6 ETO17039.1 - 1.3 9.0 22.7 5.6 7.0 10.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF755) MscS_porin PF12795.2 ETO17039.1 - 1.4 8.2 24.4 2.9 7.1 3.0 2.7 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain CMV_1a PF12467.3 ETO17039.1 - 1.8 8.9 14.5 0.13 12.6 5.5 1.9 1 1 1 2 2 2 0 Cucumber mosaic virus 1a protein family Cep57_CLD PF14073.1 ETO17039.1 - 3.3 7.5 24.6 10 5.8 16.5 1.9 1 1 0 1 1 1 0 Centrosome localisation domain of Cep57 Fib_alpha PF08702.5 ETO17039.1 - 3.9 7.5 23.3 0.046 13.8 1.8 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF948 PF06103.6 ETO17039.1 - 6.1 6.7 9.6 0.17 11.7 0.7 2.2 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DENN PF02141.16 ETO17041.1 - 0.00019 21.1 0.0 0.00024 20.8 0.0 1.2 1 0 0 1 1 1 1 DENN (AEX-3) domain Tctex-1 PF03645.8 ETO17041.1 - 0.0029 17.4 0.3 0.0036 17.1 0.2 1.1 1 0 0 1 1 1 1 Tctex-1 family CDC45 PF02724.9 ETO17044.1 - 0.011 13.8 7.2 0.013 13.6 5.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Catalase-rel PF06628.7 ETO17044.1 - 0.097 12.5 0.8 0.19 11.6 0.4 1.6 1 1 0 1 1 1 0 Catalase-related immune-responsive Nop14 PF04147.7 ETO17044.1 - 0.14 10.0 15.8 0.16 9.8 10.9 1.0 1 0 0 1 1 1 0 Nop14-like family Trypan_PARP PF05887.6 ETO17044.1 - 0.72 9.6 8.2 0.97 9.2 5.7 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3537 PF12056.3 ETO17044.1 - 0.87 8.2 4.4 1.2 7.8 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) BCAS3 PF12490.3 ETO17044.1 - 2.6 7.2 10.1 3.2 6.9 7.0 1.1 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 Daxx PF03344.10 ETO17044.1 - 2.8 6.3 14.2 3.2 6.1 9.8 1.0 1 0 0 1 1 1 0 Daxx Family DUF1754 PF08555.5 ETO17044.1 - 3 8.5 10.1 4.2 8.0 7.0 1.3 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) PQ-loop PF04193.9 ETO17045.1 - 6.6e-31 105.6 16.3 2.5e-16 58.9 2.5 3.1 3 0 0 3 3 3 2 PQ loop repeat Pox_A14 PF05767.7 ETO17045.1 - 0.037 13.9 0.5 0.037 13.9 0.3 3.0 2 2 1 3 3 3 0 Poxvirus virion envelope protein A14 GWT1 PF06423.7 ETO17045.1 - 0.6 10.1 7.3 0.96 9.5 4.2 2.0 1 1 0 1 1 1 0 GWT1 DUF3278 PF11683.3 ETO17045.1 - 5.1 7.1 8.0 0.92 9.5 0.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3278) PBP1_TM PF14812.1 ETO17046.1 - 0.061 13.6 1.1 0.061 13.6 0.7 3.7 5 0 0 5 5 5 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 ETO17046.1 - 0.5 10.6 5.8 0.15 12.2 1.0 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain zf-H2C2_2 PF13465.1 ETO17047.1 - 1.1e-06 28.6 6.6 0.054 13.8 0.2 3.9 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 ETO17047.1 - 0.00051 20.2 9.6 0.17 12.2 0.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETO17047.1 - 0.007 16.6 12.3 0.16 12.3 0.2 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-BED PF02892.10 ETO17047.1 - 0.0092 15.7 3.3 0.027 14.2 2.3 1.9 1 0 0 1 1 1 1 BED zinc finger zf-Di19 PF05605.7 ETO17047.1 - 0.49 10.5 3.6 3 8.0 2.5 2.2 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF2413 PF10310.4 ETO17047.1 - 1.7 7.3 5.9 1.8 7.2 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF1201 PF06716.6 ETO17050.1 - 0.035 13.9 0.0 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1201) Josephin PF02099.12 ETO17052.1 - 1e-10 41.4 0.2 1.2e-10 41.1 0.2 1.1 1 0 0 1 1 1 1 Josephin Vps35 PF03635.12 ETO17053.1 - 1.1e-57 195.7 9.3 1.2e-57 195.6 6.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Pep3_Vps18 PF05131.9 ETO17053.1 - 0.25 10.7 2.6 0.38 10.1 0.4 1.9 1 1 1 2 2 2 0 Pep3/Vps18/deep orange family OMP_b-brl PF13505.1 ETO17054.1 - 0.022 14.7 0.7 0.036 14.0 0.5 1.4 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain Uds1 PF15456.1 ETO17054.1 - 4 7.4 8.4 2.2 8.3 1.1 2.3 1 1 1 2 2 2 0 Up-regulated During Septation zf-U1 PF06220.7 ETO17055.1 - 9.3e-08 31.5 1.0 9.3e-08 31.5 0.7 1.8 2 0 0 2 2 2 1 U1 zinc finger AKAP95 PF04988.7 ETO17055.1 - 0.00027 20.7 1.0 0.00053 19.8 0.7 1.6 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) D5_N PF08706.6 ETO17055.1 - 0.0071 16.4 0.0 0.01 15.9 0.0 1.4 1 1 0 1 1 1 1 D5 N terminal like PTR PF12789.2 ETO17055.1 - 0.038 13.8 1.5 0.084 12.7 1.0 1.6 1 0 0 1 1 1 0 Phage tail repeat like GvpL_GvpF PF06386.6 ETO17055.1 - 0.058 12.9 1.6 0.15 11.6 1.1 1.8 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF zf-C2H2_jaz PF12171.3 ETO17055.1 - 5.4 7.2 6.5 31 4.8 4.5 2.3 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding TPR_17 PF13431.1 ETO17056.1 - 9.2e-05 22.3 4.3 0.018 15.2 0.4 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO17056.1 - 0.00051 19.6 7.3 0.017 14.7 1.0 3.2 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 ETO17056.1 - 0.054 13.4 4.0 0.32 11.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETO17056.1 - 0.11 13.2 0.0 2 9.2 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETO17056.1 - 0.11 12.4 2.6 3.4 7.6 0.7 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETO17056.1 - 0.13 12.9 0.2 2 9.2 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETO17056.1 - 0.99 9.1 7.9 7.2 6.3 0.3 4.1 3 1 0 3 3 3 0 Tetratricopeptide repeat PRY PF13765.1 ETO17057.1 - 0.093 12.2 0.0 11 5.6 0.0 2.7 2 0 0 2 2 2 0 SPRY-associated domain DWNN PF08783.6 ETO17057.1 - 4.9 7.1 6.9 17 5.4 1.4 2.8 3 0 0 3 3 3 0 DWNN domain DUF4024 PF13216.1 ETO17057.1 - 5.3 6.9 8.0 8.5 6.2 1.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4024) Sulfatase PF00884.18 ETO17058.1 - 1.1e-30 106.8 0.0 1.5e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 ETO17058.1 - 0.0079 16.4 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Exostosin PF03016.10 ETO17060.1 - 5.7e-14 51.8 0.8 3.3e-13 49.3 0.0 2.0 1 1 1 2 2 2 1 Exostosin family STAT_alpha PF01017.15 ETO17060.1 - 0.096 12.3 0.3 0.16 11.6 0.2 1.3 1 0 0 1 1 1 0 STAT protein, all-alpha domain GATase_4 PF13230.1 ETO17061.1 - 0.12 10.9 0.0 0.13 10.9 0.0 1.0 1 0 0 1 1 1 0 Glutamine amidotransferases class-II DUF3550 PF12070.3 ETO17062.1 - 0.09 11.5 2.5 0.19 10.4 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3550/UPF0682) COX6B PF02297.12 ETO17063.1 - 0.0039 17.1 3.2 0.01 15.8 2.2 1.7 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb DUF4591 PF15261.1 ETO17063.1 - 0.028 14.6 2.0 0.047 13.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4591) Occludin_ELL PF07303.8 ETO17063.1 - 0.17 12.6 9.5 0.22 12.2 0.2 3.0 3 0 0 3 3 3 0 Occludin homology domain U1snRNP70_N PF12220.3 ETO17063.1 - 8.3 6.8 10.6 0.41 11.0 1.3 2.7 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal WD40 PF00400.27 ETO17064.1 - 3.5e-09 36.1 6.7 5.3e-06 26.1 0.0 3.2 4 0 0 4 4 4 2 WD domain, G-beta repeat ICMT PF04140.9 ETO17064.1 - 0.012 15.7 0.8 0.019 15.1 0.1 1.7 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF2171 PF09939.4 ETO17065.1 - 0.017 15.1 5.0 0.021 14.8 2.8 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2171) TraU PF06834.6 ETO17065.1 - 0.2 10.7 1.2 0.21 10.6 0.8 1.1 1 0 0 1 1 1 0 TraU protein Serinc PF03348.10 ETO17065.1 - 0.69 8.5 4.8 0.79 8.3 3.3 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) SID-1_RNA_chan PF13965.1 ETO17065.1 - 0.9 7.6 6.6 1.1 7.3 4.6 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FLO_LFY PF01698.11 ETO17065.1 - 1.1 8.0 10.2 1.3 7.8 7.1 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF2207 PF09972.4 ETO17065.1 - 1.9 6.9 13.7 2.1 6.8 9.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) HlyD_2 PF12700.2 ETO17065.1 - 2 7.4 13.5 2.4 7.2 9.4 1.0 1 0 0 1 1 1 0 HlyD family secretion protein HSP70 PF00012.15 ETO17065.1 - 2.1 6.1 11.3 2.5 5.9 7.8 1.0 1 0 0 1 1 1 0 Hsp70 protein HCO3_cotransp PF00955.16 ETO17065.1 - 3.5 6.1 5.1 3.7 6.0 3.6 1.0 1 0 0 1 1 1 0 HCO3- transporter family DUF3474 PF11960.3 ETO17065.1 - 5 7.1 6.9 5.8 6.9 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) Sec62 PF03839.11 ETO17065.1 - 6.3 6.1 22.8 8 5.7 15.8 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Neur_chan_memb PF02932.11 ETO17065.1 - 7.3 6.3 7.8 8 6.2 5.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TINF2_N PF14973.1 ETO17065.1 - 7.4 6.6 11.8 12 6.0 8.2 1.4 1 1 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus WD40 PF00400.27 ETO17066.1 - 1.7e-63 208.3 21.4 4.4e-11 42.2 0.6 7.4 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO17066.1 - 4.6e-15 54.7 9.0 0.00041 18.6 0.1 6.0 2 2 4 6 6 6 6 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO17066.1 - 8.9e-05 21.4 17.0 0.19 10.4 0.1 4.7 1 1 3 5 5 5 3 Nup133 N terminal like DUF2559 PF10832.3 ETO17066.1 - 0.24 11.2 1.6 23 4.9 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2559) zf-C2H2_4 PF13894.1 ETO17067.1 - 0.0011 19.1 1.4 0.0033 17.6 1.0 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 ETO17067.1 - 0.0019 18.4 2.9 0.0019 18.4 2.0 2.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETO17067.1 - 0.0063 16.7 9.4 0.31 11.3 4.6 2.7 2 0 0 2 2 2 1 Zinc-finger double domain GAGA PF09237.6 ETO17067.1 - 0.013 15.0 0.1 0.026 14.0 0.1 1.5 1 0 0 1 1 1 0 GAGA factor Rad50_zn_hook PF04423.9 ETO17067.1 - 0.013 14.9 0.2 0.028 13.8 0.1 1.6 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-C2H2_jaz PF12171.3 ETO17067.1 - 0.014 15.5 0.4 0.014 15.5 0.3 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-like PF04071.7 ETO17067.1 - 0.017 14.8 0.9 0.034 13.8 0.5 1.6 2 0 0 2 2 2 0 Cysteine-rich small domain zf-C2H2_2 PF12756.2 ETO17067.1 - 0.017 15.2 4.9 0.024 14.7 3.2 1.5 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Toxin_46 PF15526.1 ETO17067.1 - 0.076 13.1 2.9 0.15 12.2 2.0 1.5 1 0 0 1 1 1 0 Putative toxin 46 zf-BED PF02892.10 ETO17067.1 - 1.9 8.2 7.4 1.6 8.5 3.0 2.1 2 0 0 2 2 2 0 BED zinc finger Proteasome PF00227.21 ETO17068.1 - 4.3e-49 166.3 0.4 4.3e-49 166.3 0.3 2.0 2 0 0 2 2 2 1 Proteasome subunit Guanylate_kin PF00625.16 ETO17068.1 - 2.2e-19 69.5 0.0 5.9e-19 68.2 0.0 1.8 1 0 0 1 1 1 1 Guanylate kinase G-alpha PF00503.15 ETO17068.1 - 6e-16 58.1 6.5 6e-16 58.1 4.5 2.7 3 1 0 3 3 3 1 G-protein alpha subunit AAA PF00004.24 ETO17068.1 - 0.0008 19.6 0.6 0.87 9.7 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETO17068.1 - 0.0033 17.5 0.1 0.053 13.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 ETO17068.1 - 0.011 15.5 0.0 0.031 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 ETO17068.1 - 0.013 16.0 0.2 9.5 6.7 0.0 3.2 2 0 0 2 2 2 0 Miro-like protein AAA_18 PF13238.1 ETO17068.1 - 0.037 14.3 0.1 0.23 11.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 ETO17068.1 - 0.05 14.4 0.0 0.34 11.7 0.0 2.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 ETO17068.1 - 0.092 12.2 0.0 6.9 6.2 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.22 ETO17068.1 - 0.64 10.3 3.6 2.7 8.2 0.0 3.5 4 0 0 4 4 4 0 ABC transporter PGG PF13962.1 ETO17070.1 - 0.031 13.8 0.1 0.76 9.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function WD40 PF00400.27 ETO17072.1 - 0.056 13.3 4.7 2.1 8.3 0.1 4.4 4 0 0 4 4 4 0 WD domain, G-beta repeat PyrBI_leader PF08052.6 ETO17072.1 - 0.058 13.2 0.2 0.25 11.1 0.1 2.1 1 0 0 1 1 1 0 PyrBI operon leader peptide WD40 PF00400.27 ETO17073.1 - 5.7e-15 54.5 6.2 3e-09 36.4 0.8 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Mucin PF01456.12 ETO17073.1 - 0.015 15.0 14.3 0.019 14.7 9.9 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein EIIA-man PF03610.11 ETO17073.1 - 0.098 12.7 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 PTS system fructose IIA component TMEM154 PF15102.1 ETO17073.1 - 0.3 10.7 6.2 0.42 10.3 4.3 1.2 1 0 0 1 1 1 0 TMEM154 protein family Herpes_UL47 PF03362.8 ETO17073.1 - 0.33 9.2 3.6 0.41 8.9 2.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL47 protein SSP160 PF06933.6 ETO17073.1 - 0.37 8.7 13.4 0.44 8.4 9.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 ETO17073.1 - 3.3 7.4 11.3 5.3 6.8 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Pox_A12 PF04651.8 ETO17074.1 - 0.25 11.4 7.1 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A12 protein Paramyxo_ncap PF00973.14 ETO17074.1 - 5 5.6 10.9 8.3 4.9 7.6 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CLASP_N PF12348.3 ETO17075.1 - 1.3e-17 63.9 1.8 1.3e-17 63.9 1.3 2.1 2 0 0 2 2 2 1 CLASP N terminal EF-hand_1 PF00036.27 ETO17075.1 - 1.3e-13 49.1 5.0 0.0033 16.6 0.3 5.6 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 ETO17075.1 - 2.2e-11 42.6 3.6 0.016 15.0 0.2 5.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 ETO17075.1 - 6.5e-09 35.7 5.0 0.29 11.2 0.2 4.9 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_8 PF13833.1 ETO17075.1 - 8.5e-08 31.7 4.8 0.005 16.4 0.0 4.7 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 ETO17075.1 - 0.074 12.4 1.2 37 3.8 0.0 4.3 4 0 0 4 4 4 0 EF hand p25-alpha PF05517.7 ETO17075.1 - 0.075 13.2 8.3 2.1 8.5 0.1 3.5 2 1 1 3 3 3 0 p25-alpha CCDC-167 PF15188.1 ETO17076.1 - 0.069 13.1 0.3 0.069 13.1 0.2 2.2 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 zf-Nse PF11789.3 ETO17077.1 - 3.9e-14 51.9 0.1 9.2e-14 50.7 0.1 1.7 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 ETO17077.1 - 0.00043 20.0 0.1 0.00082 19.1 0.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-MIZ PF02891.15 ETO17077.1 - 0.0017 17.7 5.4 0.0084 15.5 3.7 2.2 1 1 0 1 1 1 1 MIZ/SP-RING zinc finger Spore_permease PF03845.8 ETO17077.1 - 0.0023 16.6 3.6 0.0034 16.0 2.5 1.2 1 0 0 1 1 1 1 Spore germination protein zf-RING_UBOX PF13445.1 ETO17077.1 - 0.0095 15.6 0.0 0.0095 15.6 0.0 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 ETO17077.1 - 0.13 12.3 1.0 0.39 10.8 0.7 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger DUF2146 PF10220.4 ETO17077.1 - 0.27 9.1 8.0 0.37 8.7 5.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) SR-25 PF10500.4 ETO17077.1 - 1.8 7.9 16.9 0.075 12.4 7.8 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CENP-Q PF13094.1 ETO17078.1 - 0.0059 16.6 8.1 0.031 14.2 0.9 3.1 2 1 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF2203 PF09969.4 ETO17078.1 - 0.018 15.2 4.9 0.32 11.2 0.8 3.0 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) Glyco_hydro_67C PF07477.7 ETO17078.1 - 0.018 14.4 0.9 2.2 7.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 67 C-terminus Fib_alpha PF08702.5 ETO17078.1 - 0.037 14.1 6.6 0.19 11.8 3.0 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family IL4 PF00727.13 ETO17078.1 - 0.1 12.4 1.4 4.1 7.2 0.1 2.6 2 0 0 2 2 2 0 Interleukin 4 DUF948 PF06103.6 ETO17078.1 - 0.22 11.3 3.9 4.6 7.1 0.1 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Syntaxin PF00804.20 ETO17078.1 - 0.24 11.5 11.6 1.6 8.9 3.7 3.4 1 1 1 2 2 2 0 Syntaxin RPA_interact_N PF14766.1 ETO17078.1 - 0.3 10.6 6.0 0.51 9.8 0.3 2.9 3 0 0 3 3 3 0 Replication protein A interacting N-terminal AKNA PF12443.3 ETO17078.1 - 0.48 10.4 7.3 2.7 8.0 0.3 3.6 3 1 0 3 3 3 0 AT-hook-containing transcription factor AAA_13 PF13166.1 ETO17078.1 - 0.49 8.7 16.1 0.097 11.1 7.8 1.8 1 1 1 2 2 2 0 AAA domain CheZ PF04344.8 ETO17078.1 - 0.88 9.1 9.1 0.48 10.0 0.9 2.8 1 1 1 3 3 3 0 Chemotaxis phosphatase, CheZ DUF972 PF06156.8 ETO17078.1 - 0.93 9.8 10.2 6.5 7.1 0.9 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF972) UN_NPL4 PF11543.3 ETO17079.1 - 0.11 12.7 0.5 0.32 11.3 0.1 1.9 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 TPR_1 PF00515.23 ETO17080.1 - 3.7e-06 26.3 0.2 0.013 15.1 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO17080.1 - 4.5e-06 26.2 1.0 1.4e-05 24.6 0.7 1.8 1 1 0 1 1 1 1 TPR repeat TPR_17 PF13431.1 ETO17080.1 - 0.00043 20.2 0.9 0.36 11.1 0.0 3.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO17080.1 - 0.00097 18.8 0.1 0.57 10.2 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO17080.1 - 0.013 15.2 0.0 1.8 8.5 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETO17080.1 - 0.014 15.1 0.1 0.2 11.5 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETO17080.1 - 0.015 15.9 0.0 0.024 15.2 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETO17080.1 - 0.099 12.5 0.9 7.8 6.5 0.2 2.2 1 1 0 1 1 1 0 Tetratricopeptide repeat Ribosomal_L39 PF00832.15 ETO17081.1 - 1.1 8.7 4.9 2.3 7.7 3.4 1.6 1 1 0 1 1 1 0 Ribosomal L39 protein RabGAP-TBC PF00566.13 ETO17082.1 - 2.9e-23 82.4 5.1 7.6e-21 74.5 0.1 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain BNIP2 PF12496.3 ETO17082.1 - 0.015 15.4 1.1 0.032 14.4 0.2 1.9 1 1 1 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DUF4615 PF15393.1 ETO17082.1 - 0.18 12.0 7.8 0.28 11.4 4.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4615) Dicty_REP PF05086.7 ETO17082.1 - 0.25 9.0 6.2 0.32 8.7 4.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PIP5K PF01504.13 ETO17084.1 - 2.1e-31 108.9 0.0 2.6e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Methyltransf_4 PF02390.12 ETO17085.1 - 0.012 14.6 2.6 0.11 11.5 0.0 2.3 2 0 0 2 2 2 0 Putative methyltransferase Protocadherin PF08374.6 ETO17085.1 - 0.017 14.7 5.5 0.023 14.3 3.8 1.2 1 0 0 1 1 1 0 Protocadherin Aida_N PF08910.5 ETO17085.1 - 0.8 9.9 5.2 3.3 7.9 3.3 1.9 2 0 0 2 2 2 0 Aida N-terminus DUF1764 PF08576.5 ETO17085.1 - 1.1 10.0 10.4 2 9.2 7.2 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF2532 PF10811.3 ETO17087.1 - 0.021 14.6 0.5 0.03 14.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2532) Ferrochelatase PF00762.14 ETO17087.1 - 0.1 11.5 0.0 0.12 11.3 0.0 1.0 1 0 0 1 1 1 0 Ferrochelatase DUF735 PF05246.6 ETO17087.1 - 0.1 12.3 0.3 0.13 11.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF735) CpcD PF01383.16 ETO17087.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 CpcD/allophycocyanin linker domain Cpn60_TCP1 PF00118.19 ETO17090.1 - 4.5e-24 84.9 0.4 5.2e-24 84.7 0.3 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NIT PF08376.5 ETO17090.1 - 0.088 12.3 0.0 2 7.8 0.0 2.2 2 0 0 2 2 2 0 Nitrate and nitrite sensing Secretin_N_2 PF07655.8 ETO17092.1 - 0.0031 17.8 10.6 0.0031 17.8 7.4 1.6 2 0 0 2 2 2 1 Secretin N-terminal domain ATG27 PF09451.5 ETO17092.1 - 0.008 15.4 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 PAT1 PF09770.4 ETO17092.1 - 0.45 8.6 35.7 0.6 8.2 24.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF35 PF01796.12 ETO17092.1 - 0.49 10.6 2.9 3.5 7.9 0.1 2.7 2 1 0 2 2 2 0 DUF35 OB-fold domain Eapp_C PF10238.4 ETO17092.1 - 0.56 10.1 9.5 0.35 10.7 3.8 2.1 2 0 0 2 2 2 0 E2F-associated phosphoprotein POX PF07526.6 ETO17092.1 - 0.73 10.0 7.8 0.11 12.7 1.3 2.0 2 0 0 2 2 2 0 Associated with HOX DUF912 PF06024.7 ETO17092.1 - 3.3 7.8 10.8 1.1 9.3 3.7 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Daxx PF03344.10 ETO17094.1 - 0.0051 15.3 15.5 0.0068 14.9 10.8 1.1 1 0 0 1 1 1 1 Daxx Family eIF_4EBP PF05456.6 ETO17094.1 - 0.062 13.0 0.5 0.15 11.7 0.3 1.7 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DUF2457 PF10446.4 ETO17094.1 - 0.09 11.4 20.1 0.19 10.4 13.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FLO_LFY PF01698.11 ETO17094.1 - 0.41 9.4 5.8 0.49 9.1 4.0 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein MMR1 PF08505.5 ETO17094.1 - 3.1 7.7 12.2 6.8 6.6 8.4 1.5 1 1 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein NPR3 PF03666.8 ETO17094.1 - 4.3 5.7 7.3 34 2.8 5.6 1.8 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Ycf1 PF05758.7 ETO17094.1 - 4.9 4.7 7.5 6.1 4.4 5.2 1.1 1 0 0 1 1 1 0 Ycf1 ERAP1_C PF11838.3 ETO17095.1 - 2.5e-13 49.9 0.2 2.6e-12 46.6 0.1 2.0 1 1 0 1 1 1 1 ERAP1-like C-terminal domain EIAV_GP90 PF00971.13 ETO17095.1 - 0.048 12.1 3.0 0.31 9.4 0.4 2.0 2 0 0 2 2 2 0 EIAV coat protein, gp90 MIB_HERC2 PF06701.8 ETO17096.1 - 1.5e-21 76.1 18.5 2.1e-18 66.0 2.4 4.7 5 0 0 5 5 5 3 Mib_herc2 RhoGEF PF00621.15 ETO17097.1 - 1.4e-16 60.8 4.7 1.7e-16 60.6 3.3 1.1 1 0 0 1 1 1 1 RhoGEF domain DUF3800 PF12686.2 ETO17097.1 - 0.016 14.9 3.2 0.018 14.7 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3800) PB1-F2 PF11986.3 ETO17098.1 - 0.24 11.4 8.6 0.4 10.7 5.9 1.3 1 1 0 1 1 1 0 Influenza A Proapoptotic protein DUF3128 PF11326.3 ETO17098.1 - 9.5 6.4 10.0 44 4.3 6.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) DUF2360 PF10152.4 ETO17099.1 - 2.1e-08 34.5 12.4 1.5e-05 25.3 0.3 2.5 3 0 0 3 3 3 2 Predicted coiled-coil domain-containing protein (DUF2360) Zn_ribbon_2 PF12674.2 ETO17099.1 - 0.099 13.0 0.6 0.099 13.0 0.4 2.0 2 0 0 2 2 2 0 Putative zinc ribbon domain RNA_pol_Rpb1_5 PF04998.12 ETO17099.1 - 4.4 6.4 6.2 6.2 5.9 4.3 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 MRP-S27 PF10037.4 ETO17100.1 - 0.057 12.3 1.7 0.068 12.0 1.2 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Vpu PF00558.14 ETO17100.1 - 0.84 9.2 4.9 0.97 9.0 2.6 1.7 1 1 1 2 2 2 0 Vpu protein U1snRNP70_N PF12220.3 ETO17100.1 - 0.85 9.9 6.7 1.7 8.9 4.4 1.7 1 1 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Exo_endo_phos PF03372.18 ETO17102.1 - 3.4e-23 82.8 0.0 5.5e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-MYND PF01753.13 ETO17102.1 - 0.48 10.3 21.2 0.026 14.4 10.0 2.4 2 0 0 2 2 2 0 MYND finger GOLD_2 PF13897.1 ETO17102.1 - 3.9 7.6 15.3 0.28 11.4 0.3 3.4 3 0 0 3 3 3 0 Golgi-dynamics membrane-trafficking Nucleoplasmin PF03066.10 ETO17103.1 - 0.24 10.9 14.8 0.17 11.3 6.4 2.1 2 0 0 2 2 2 0 Nucleoplasmin BSP_II PF05432.6 ETO17103.1 - 0.45 9.7 6.2 0.55 9.4 4.3 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CENP-B_dimeris PF09026.5 ETO17103.1 - 1.1 9.5 18.6 0.64 10.2 7.7 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain SDA1 PF05285.7 ETO17103.1 - 6.3 5.9 11.1 8.6 5.5 7.7 1.1 1 0 0 1 1 1 0 SDA1 DUF2654 PF10849.3 ETO17104.1 - 0.03 14.0 0.5 0.08 12.6 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2654) DUF1192 PF06698.6 ETO17104.1 - 0.13 12.0 5.8 5.4 6.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) NifQ PF04891.7 ETO17104.1 - 0.36 10.9 4.5 6.5 6.8 2.9 2.3 1 1 0 1 1 1 0 NifQ Muted PF14942.1 ETO17104.1 - 5.8 6.7 19.5 0.028 14.3 3.8 2.3 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein SAM_2 PF07647.12 ETO17105.1 - 0.084 12.7 0.2 0.13 12.1 0.1 1.4 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) ATP-synt_F PF01990.12 ETO17106.1 - 0.021 15.1 0.4 0.025 14.9 0.3 1.2 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit DUF3017 PF11222.3 ETO17106.1 - 0.022 14.5 0.7 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3017) DUF1697 PF08002.6 ETO17106.1 - 0.075 13.0 0.2 0.097 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1697) EF-hand_1 PF00036.27 ETO17107.1 - 8.6e-28 93.5 15.5 4.1e-07 28.8 0.6 4.6 4 0 0 4 4 4 4 EF hand Pkinase PF00069.20 ETO17107.1 - 1.9e-25 89.4 0.1 1e-24 87.1 0.0 2.1 3 0 0 3 3 3 1 Protein kinase domain EF-hand_5 PF13202.1 ETO17107.1 - 5.8e-24 82.3 9.9 1.2e-05 24.3 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 ETO17107.1 - 1.5e-23 82.6 6.2 2.9e-12 46.5 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO17107.1 - 6.8e-22 75.3 12.2 1.1e-06 27.9 0.1 4.8 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 ETO17107.1 - 6.2e-19 67.3 8.0 4e-05 23.1 0.1 4.5 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 ETO17107.1 - 8.7e-11 41.8 2.1 1.7e-05 24.8 0.1 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Pkinase_Tyr PF07714.12 ETO17107.1 - 7.6e-07 28.4 0.0 2.3e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase EF-hand_4 PF12763.2 ETO17107.1 - 0.032 13.9 5.7 0.79 9.4 0.3 3.3 1 1 3 4 4 4 0 Cytoskeletal-regulatory complex EF hand EF-hand_like PF09279.6 ETO17107.1 - 0.055 13.5 0.9 0.28 11.2 0.0 2.6 2 2 1 3 3 3 0 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_10 PF14788.1 ETO17107.1 - 0.4 10.3 8.0 3.8 7.2 0.2 4.1 3 1 1 4 4 4 0 EF hand HALZ PF02183.13 ETO17108.1 - 2.2e-05 24.0 5.6 2.2e-05 24.0 3.9 2.2 2 1 1 3 3 3 1 Homeobox associated leucine zipper DUF342 PF03961.8 ETO17108.1 - 0.021 13.2 14.7 0.035 12.5 10.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) bZIP_1 PF00170.16 ETO17108.1 - 0.041 13.8 5.2 0.041 13.8 3.6 2.9 1 1 1 2 2 2 0 bZIP transcription factor Syntaxin-18_N PF10496.4 ETO17108.1 - 0.56 10.0 6.6 0.09 12.6 1.6 1.9 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus V_ATPase_I PF01496.14 ETO17108.1 - 0.6 7.8 7.5 0.74 7.5 5.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 ETO17108.1 - 0.82 10.0 15.8 0.25 11.6 5.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF1640 PF07798.6 ETO17108.1 - 1 9.3 17.2 85 3.1 11.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Ribosomal_L23 PF00276.15 ETO17108.1 - 1.1 9.2 5.8 0.12 12.3 0.5 2.2 2 1 0 2 2 2 0 Ribosomal protein L23 Phlebovirus_NSM PF07246.6 ETO17108.1 - 1.3 8.0 12.8 2.4 7.2 8.9 1.4 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Phage_GPO PF05929.6 ETO17108.1 - 6.7 5.8 8.2 14 4.8 5.7 1.6 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase CD36 PF01130.16 ETO17110.1 - 4e-08 32.0 6.4 7.6e-07 27.7 4.4 2.0 1 1 0 1 1 1 1 CD36 family DUF2721 PF11026.3 ETO17110.1 - 0.075 12.6 0.2 0.075 12.6 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) zf-DHHC PF01529.15 ETO17110.1 - 1.9 7.8 8.4 2.5 7.4 5.8 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Aa_trans PF01490.13 ETO17111.1 - 1.5e-09 36.8 5.2 5e-09 35.1 2.3 2.1 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein DUF1183 PF06682.7 ETO17111.1 - 0.00028 20.5 0.1 0.19 11.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1183) YMF19 PF02326.10 ETO17111.1 - 0.045 14.3 3.2 0.099 13.2 0.6 2.9 2 0 0 2 2 2 0 Plant ATP synthase F0 SID-1_RNA_chan PF13965.1 ETO17111.1 - 0.16 10.0 14.7 0.13 10.4 0.1 3.2 2 1 1 3 3 3 0 dsRNA-gated channel SID-1 Gly-zipper_OmpA PF13436.1 ETO17111.1 - 0.23 11.1 3.3 0.58 9.8 2.3 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain DUF843 PF05814.6 ETO17111.1 - 0.62 9.9 9.6 7.4 6.4 0.0 3.7 3 0 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) Baculo_11_kDa PF06143.6 ETO17111.1 - 9.1 5.7 8.3 3.7 6.9 1.8 2.8 2 0 0 2 2 2 0 Baculovirus 11 kDa family HECT PF00632.20 ETO17114.1 - 3.1e-83 279.5 0.0 3.1e-83 279.5 0.0 2.0 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) RCC1 PF00415.13 ETO17114.1 - 1.4e-12 47.6 3.1 6.6e-05 23.0 0.0 3.6 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO17114.1 - 4.7e-08 32.4 6.1 1.9e-05 24.1 1.5 2.8 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO17115.1 - 2.3e-08 33.4 1.2 0.00043 19.8 0.0 2.4 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 ETO17115.1 - 4e-07 30.1 2.5 0.00012 22.1 0.0 2.6 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat Ripply PF14998.1 ETO17115.1 - 3.2 7.9 8.3 0.14 12.2 0.3 2.7 2 1 0 2 2 2 0 Transcription Regulator adh_short PF00106.20 ETO17116.1 - 1.2e-15 57.8 0.0 2.4e-15 56.8 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETO17116.1 - 0.00024 20.9 0.0 0.0007 19.4 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 ETO17116.1 - 0.017 14.8 0.0 0.088 12.6 0.0 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase UCH PF00443.24 ETO17117.1 - 7.9e-31 107.1 1.0 7.9e-31 107.1 0.7 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO17117.1 - 8.3e-16 58.2 0.1 8.3e-16 58.2 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_M75 PF09375.5 ETO17118.1 - 0.025 13.8 0.4 0.078 12.2 0.0 1.9 2 1 0 2 2 2 0 Imelysin SRP-alpha_N PF04086.8 ETO17118.1 - 0.37 10.1 15.5 0.52 9.6 10.7 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CDK5_activator PF03261.10 ETO17120.1 - 0.3 10.3 7.6 0.38 10.0 5.3 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein SID-1_RNA_chan PF13965.1 ETO17120.1 - 0.43 8.6 2.4 0.6 8.2 1.7 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CENP-B_dimeris PF09026.5 ETO17120.1 - 1.8 8.8 13.5 6.2 7.1 0.1 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Herpes_LMP1 PF05297.6 ETO17120.1 - 1.9 7.3 7.8 2.7 6.8 5.4 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) FYDLN_acid PF09538.5 ETO17120.1 - 2.4 8.7 15.3 0.64 10.6 5.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Dicty_REP PF05086.7 ETO17120.1 - 3.7 5.1 9.0 5.2 4.6 6.2 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Serinc PF03348.10 ETO17120.1 - 4.6 5.8 11.6 0.29 9.7 4.5 1.6 2 0 0 2 2 2 0 Serine incorporator (Serinc) DUF1510 PF07423.6 ETO17120.1 - 6 6.1 22.9 0.4 10.0 7.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Sec20 PF03908.8 ETO17122.1 - 0.47 10.1 0.0 0.47 10.1 0.0 3.0 4 0 0 4 4 4 0 Sec20 RGS PF00615.14 ETO17124.1 - 7.9e-07 29.1 0.8 1.1e-06 28.7 0.5 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain HDA2-3 PF11496.3 ETO17124.1 - 0.075 11.8 0.6 0.13 11.0 0.4 1.3 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 DUF2962 PF11176.3 ETO17124.1 - 1.5 8.3 5.9 17 4.9 2.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2962) TPR_11 PF13414.1 ETO17125.1 - 2.3e-22 78.4 9.7 0.00011 21.8 0.0 5.2 4 1 0 5 5 5 4 TPR repeat TPR_2 PF07719.12 ETO17125.1 - 3.4e-13 48.4 21.0 0.0022 17.7 0.1 6.9 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO17125.1 - 2.8e-11 42.4 22.9 0.0011 18.5 0.6 6.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 ETO17125.1 - 1.8e-09 37.4 2.1 0.0044 16.9 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO17125.1 - 3.8e-09 36.3 0.4 0.038 14.6 0.0 5.1 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO17125.1 - 8.3e-09 35.8 0.0 0.12 13.1 0.0 5.2 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO17125.1 - 3.4e-08 32.6 10.6 0.057 13.2 0.3 5.4 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO17125.1 - 1.7e-06 28.2 1.2 0.025 14.8 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO17125.1 - 4.5e-06 26.7 14.3 0.0061 16.6 0.1 4.9 5 0 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 ETO17125.1 - 0.00083 19.3 7.0 0.036 14.2 0.1 5.8 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETO17125.1 - 0.0018 18.0 0.1 2.6 7.9 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO17125.1 - 0.02 14.6 4.5 2.7 8.0 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Rad21_Rec8_N PF04825.8 ETO17125.1 - 0.047 13.6 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 N terminus of Rad21 / Rec8 like protein CDC45 PF02724.9 ETO17125.1 - 0.055 11.5 6.0 0.078 11.0 4.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Fis1_TPR_C PF14853.1 ETO17125.1 - 0.074 12.9 1.9 14 5.6 0.1 3.3 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 ETO17125.1 - 0.4 11.2 5.2 1.1e+02 3.6 0.0 4.9 6 0 0 6 6 4 0 Tetratricopeptide repeat Sigma70_ner PF04546.8 ETO17125.1 - 0.92 9.0 10.8 1 8.9 6.1 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region WD40 PF00400.27 ETO17126.1 - 2.3e-183 588.3 52.7 1.1e-13 50.4 0.1 14.9 15 0 0 15 15 15 14 WD domain, G-beta repeat NACHT PF05729.7 ETO17126.1 - 3.9e-10 39.6 0.0 8.9e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Cytochrom_D1 PF02239.11 ETO17126.1 - 4.5e-06 25.2 13.8 0.23 9.7 0.3 5.6 1 1 4 6 6 6 4 Cytochrome D1 heme domain PD40 PF07676.7 ETO17126.1 - 7.9e-06 25.4 23.3 23 4.8 0.0 12.1 13 0 0 13 13 13 0 WD40-like Beta Propeller Repeat DUF727 PF05303.7 ETO17126.1 - 1.6e-05 24.6 4.8 4.9 6.9 0.0 9.6 9 3 3 12 12 12 1 Protein of unknown function (DUF727) AAA_18 PF13238.1 ETO17126.1 - 0.00031 21.0 0.9 0.0021 18.3 0.1 3.0 2 0 0 2 2 2 1 AAA domain Pentapeptide PF00805.17 ETO17126.1 - 0.0014 17.7 0.1 0.0027 16.9 0.1 1.4 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) AAA_22 PF13401.1 ETO17126.1 - 0.0084 16.2 0.0 0.031 14.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain SLH PF00395.15 ETO17126.1 - 0.017 14.8 0.6 40 4.0 0.1 6.1 9 0 0 9 9 9 0 S-layer homology domain BNIP2 PF12496.3 ETO17127.1 - 2.4 8.3 16.0 3 8.0 11.1 1.3 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CobT PF06213.7 ETO17127.1 - 7.9 5.5 24.8 11 5.0 17.2 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT YL1 PF05764.8 ETO17127.1 - 9.7 5.7 35.8 11 5.5 24.8 1.1 1 0 0 1 1 1 0 YL1 nuclear protein HALZ PF02183.13 ETO17128.1 - 8.6e-05 22.1 1.1 0.00022 20.8 0.7 1.7 1 0 0 1 1 1 1 Homeobox associated leucine zipper DivIC PF04977.10 ETO17128.1 - 7 6.2 9.8 2 7.9 0.9 2.7 2 0 0 2 2 2 0 Septum formation initiator ArdA PF07275.6 ETO17129.1 - 0.043 14.0 1.5 0.6 10.3 1.0 2.1 1 1 0 1 1 1 0 Antirestriction protein (ArdA) UPF0262 PF06793.7 ETO17129.1 - 0.045 13.4 1.1 0.054 13.2 0.3 1.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0262) DUF3573 PF12097.3 ETO17129.1 - 0.19 10.3 1.4 0.24 9.9 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) zf-RING_2 PF13639.1 ETO17130.1 - 3.2e-05 23.6 8.9 6.6e-05 22.6 6.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING-like PF08746.6 ETO17130.1 - 0.0027 17.6 9.8 0.0077 16.2 6.8 1.9 1 0 0 1 1 1 1 RING-like domain DUF2410 PF10307.4 ETO17130.1 - 0.021 14.2 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 Hypothetical protein (DUF2410) zf-C3HC4_3 PF13920.1 ETO17130.1 - 0.16 11.6 12.0 0.3 10.7 7.2 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.1 ETO17130.1 - 2.2 8.3 11.1 0.57 10.2 4.7 2.1 2 0 0 2 2 2 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 ETO17130.1 - 5 7.3 13.5 0.42 10.7 5.2 2.2 2 0 0 2 2 2 0 PHD-like zinc-binding domain Methyltrans_RNA PF04452.9 ETO17131.1 - 7.2e-31 107.0 0.0 4e-30 104.6 0.0 2.1 1 1 0 2 2 2 1 RNA methyltransferase DUF4611 PF15387.1 ETO17131.1 - 1.7 8.8 6.1 50 4.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) RGS PF00615.14 ETO17132.1 - 0.013 15.5 4.6 1.1 9.3 0.1 2.5 2 0 0 2 2 2 0 Regulator of G protein signaling domain Chordopox_A15 PF05846.7 ETO17133.1 - 0.042 13.8 0.2 0.11 12.6 0.0 1.7 2 0 0 2 2 2 0 Chordopoxvirus A15 protein Glyco_hydro_53 PF07745.8 ETO17134.1 - 3.4e-14 52.3 0.1 4.3e-14 52.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 RAMP4 PF06624.7 ETO17134.1 - 0.11 11.9 0.1 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 WD40 PF00400.27 ETO17135.1 - 5e-33 111.7 5.9 1.3e-10 40.6 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 ETO17135.1 - 8.2e-25 87.4 0.0 3.5e-24 85.3 0.0 1.9 2 1 1 3 3 3 1 Coatomer WD associated region DUF1510 PF07423.6 ETO17137.1 - 0.011 15.0 6.5 0.015 14.6 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TRAP_alpha PF03896.11 ETO17137.1 - 0.011 14.7 0.4 0.017 14.1 0.3 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SID-1_RNA_chan PF13965.1 ETO17137.1 - 0.062 11.4 0.8 0.075 11.1 0.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 ATP-synt_E PF05680.7 ETO17137.1 - 0.08 12.9 5.6 0.12 12.2 3.9 1.2 1 0 0 1 1 1 0 ATP synthase E chain RNA_polI_A34 PF08208.6 ETO17137.1 - 0.17 11.5 17.3 0.23 11.0 12.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Flavi_capsid PF01003.14 ETO17137.1 - 0.47 9.9 3.9 0.61 9.6 2.2 1.7 1 1 0 1 1 1 0 Flavivirus capsid protein C Protocadherin PF08374.6 ETO17137.1 - 5.2 6.6 8.1 7.1 6.2 5.6 1.1 1 0 0 1 1 1 0 Protocadherin DUF3464 PF11947.3 ETO17137.1 - 6 6.3 6.4 9.5 5.6 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) BLVR PF06375.6 ETO17138.1 - 0.022 14.5 0.7 0.028 14.2 0.5 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) mTERF PF02536.9 ETO17141.1 - 0.0002 20.0 7.0 0.0069 15.0 0.1 2.2 1 1 0 2 2 2 2 mTERF G-alpha PF00503.15 ETO17143.1 - 0.00084 18.1 0.6 0.00084 18.1 0.4 1.7 2 0 0 2 2 2 1 G-protein alpha subunit ETRAMP PF09716.5 ETO17143.1 - 0.11 12.4 0.0 0.11 12.4 0.0 3.4 4 1 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) PSI_PsaF PF02507.10 ETO17144.1 - 0.39 10.2 3.7 1.1 8.7 1.6 2.4 2 0 0 2 2 2 0 Photosystem I reaction centre subunit III DUF3782 PF12644.2 ETO17144.1 - 1.5 8.6 6.4 53 3.7 4.5 3.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) eIF3_N PF09440.5 ETO17144.1 - 2 8.5 14.5 3.1 7.9 7.4 2.7 2 1 0 2 2 2 0 eIF3 subunit 6 N terminal domain CAP_GLY PF01302.20 ETO17145.1 - 0.005 16.5 1.0 0.008 15.8 0.1 1.9 2 0 0 2 2 2 1 CAP-Gly domain PBP1_TM PF14812.1 ETO17146.1 - 2 8.7 7.9 0.44 10.8 0.4 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MT0933_antitox PF14013.1 ETO17147.1 - 0.041 14.0 3.3 0.15 12.1 2.3 2.1 1 1 0 1 1 1 0 MT0933-like antitoxin protein Gly-zipper_Omp PF13488.1 ETO17147.1 - 1.3 8.6 6.1 4.8 6.9 3.8 2.1 1 1 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.1 ETO17147.1 - 2.6 7.6 5.8 0.43 10.1 0.2 1.7 1 1 1 2 2 2 0 YMGG-like Gly-zipper Romo1 PF10247.4 ETO17147.1 - 3.5 7.8 5.7 8.2 6.6 0.7 2.6 1 1 1 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 DUF520 PF04461.8 ETO17149.1 - 0.065 13.1 4.0 0.088 12.6 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF520) ETRAMP PF09716.5 ETO17150.1 - 0.0043 16.9 0.5 0.039 13.9 0.4 2.4 1 1 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) DUF1358 PF07096.6 ETO17150.1 - 0.071 12.8 0.1 0.21 11.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1358) DUF3915 PF13054.1 ETO17150.1 - 0.11 12.4 2.1 0.29 11.1 1.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DUF2749 PF10907.3 ETO17150.1 - 0.22 11.4 1.2 7.8 6.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2749) PIG-P PF08510.7 ETO17150.1 - 0.37 10.4 4.0 4.4 6.9 0.0 2.8 2 1 0 2 2 2 0 PIG-P Mucin PF01456.12 ETO17150.1 - 0.45 10.2 10.8 1.1 8.9 7.5 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein GrpE PF01025.14 ETO17150.1 - 0.58 9.6 6.6 2.3 7.7 0.2 2.4 1 1 1 2 2 2 0 GrpE DUF912 PF06024.7 ETO17150.1 - 1.1 9.3 11.1 7.5 6.6 0.9 2.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF972 PF06156.8 ETO17150.1 - 4.4 7.6 9.9 1.6 9.0 0.5 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF4512 PF14975.1 ETO17150.1 - 7.1 7.5 7.8 2.7 8.8 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4512) Pex14_N PF04695.8 ETO17151.1 - 0.27 11.2 2.1 4.9 7.2 0.2 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SelP_N PF04592.9 ETO17151.1 - 1.8 7.9 22.7 0.16 11.3 10.9 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Ras PF00071.17 ETO17153.1 - 1.2e-29 102.8 0.2 8.7e-28 96.7 0.1 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 ETO17153.1 - 2e-05 25.0 0.0 0.0003 21.2 0.0 2.3 1 1 0 1 1 1 1 Miro-like protein PH PF00169.24 ETO17154.1 - 6.1e-13 48.8 2.8 7.7e-12 45.3 1.9 2.7 1 1 0 1 1 1 1 PH domain PH_9 PF15410.1 ETO17154.1 - 0.00029 20.9 0.4 0.03 14.4 0.0 2.9 3 0 0 3 3 3 1 Pleckstrin homology domain PH_11 PF15413.1 ETO17154.1 - 0.001 19.3 4.3 0.005 17.0 2.9 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain zf-RING_5 PF14634.1 ETO17155.1 - 0.0041 16.8 13.7 0.011 15.3 9.5 1.8 1 1 0 1 1 1 1 zinc-RING finger domain NOA36 PF06524.7 ETO17155.1 - 0.011 15.0 1.8 0.9 8.7 0.1 2.6 2 0 0 2 2 2 0 NOA36 protein zf-C3HC4_2 PF13923.1 ETO17155.1 - 0.02 14.9 11.5 0.02 14.9 8.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO17155.1 - 0.022 14.4 13.4 0.021 14.4 6.8 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 ETO17155.1 - 0.11 12.2 7.7 0.34 10.6 5.3 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.1 ETO17155.1 - 0.11 12.3 15.5 0.47 10.3 10.7 2.0 1 1 0 1 1 1 0 Ring finger domain zf-RING_6 PF14835.1 ETO17155.1 - 0.37 10.5 3.8 0.88 9.3 2.6 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Cytochrom_B_N PF00033.14 ETO17156.1 - 0.098 11.9 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB WD40 PF00400.27 ETO17157.1 - 6.5e-51 168.4 6.2 3.8e-12 45.5 0.1 5.6 5 1 1 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO17157.1 - 3.4e-05 22.1 4.8 0.77 7.8 1.6 4.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PD40 PF07676.7 ETO17157.1 - 5.9e-05 22.6 7.9 0.78 9.4 0.0 4.5 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 ETO17157.1 - 0.00014 21.0 0.2 0.19 10.7 0.0 3.3 1 1 3 4 4 4 2 Protein of unknown function (DUF1258) DUF1652 PF07865.6 ETO17157.1 - 0.00024 20.6 0.3 4.5 6.9 0.0 4.1 2 1 2 4 4 4 2 Protein of unknown function (DUF1652) Nbas_N PF15492.1 ETO17157.1 - 0.0076 15.3 0.1 0.24 10.4 0.0 2.5 1 1 1 2 2 2 1 Neuroblastoma-amplified sequence, N terminal DPPIV_N PF00930.16 ETO17157.1 - 0.0087 14.6 0.0 0.26 9.8 0.0 2.9 1 1 1 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Cytochrom_D1 PF02239.11 ETO17157.1 - 0.016 13.5 0.1 0.31 9.3 0.0 2.1 1 1 1 2 2 2 0 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO17157.1 - 0.029 13.1 0.6 1.1 7.9 0.0 2.1 2 0 0 2 2 2 0 Nup133 N terminal like Gmad1 PF10647.4 ETO17157.1 - 0.043 13.1 0.0 0.26 10.6 0.0 2.3 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain DUF4072 PF13284.1 ETO17157.1 - 0.098 12.8 0.0 53 4.0 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4072) Resistin PF06954.6 ETO17157.1 - 0.12 12.7 1.4 23 5.3 0.0 3.6 3 1 0 4 4 4 0 Resistin DUF1345 PF07077.6 ETO17158.1 - 0.035 13.6 0.5 0.035 13.6 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) DUF4083 PF13314.1 ETO17158.1 - 0.047 13.5 0.1 0.047 13.5 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) Pox_A14 PF05767.7 ETO17158.1 - 0.16 11.9 9.0 0.4 10.6 1.9 2.4 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 DUF3801 PF12687.2 ETO17161.1 - 0.031 13.8 2.7 0.062 12.8 1.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) DWNN PF08783.6 ETO17162.1 - 0.12 12.2 0.1 0.32 10.9 0.1 1.7 1 0 0 1 1 1 0 DWNN domain MIP PF00230.15 ETO17163.1 - 4.7e-11 42.5 5.8 7.5e-10 38.6 4.1 2.0 1 1 0 1 1 1 1 Major intrinsic protein DUF1340 PF07067.6 ETO17164.1 - 0.013 14.6 0.1 0.16 11.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1340) Phage_Nu1 PF07471.7 ETO17165.1 - 0.16 11.4 4.4 0.23 10.8 2.8 1.5 1 1 0 1 1 1 0 Phage DNA packaging protein Nu1 Hemerythrin PF01814.18 ETO17166.1 - 3.2e-05 24.0 0.7 0.00025 21.2 0.4 2.0 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF2294 PF10057.4 ETO17167.1 - 0.027 14.1 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2294) zf-TRAF PF02176.13 ETO17167.1 - 0.093 13.1 0.8 0.093 13.1 0.6 2.4 2 0 0 2 2 2 0 TRAF-type zinc finger ShK PF01549.19 ETO17167.1 - 0.21 11.9 6.7 0.62 10.4 0.4 2.5 2 0 0 2 2 2 0 ShK domain-like DUF1777 PF08648.7 ETO17168.1 - 0.0089 15.7 64.2 0.0089 15.7 44.5 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) Myco_arth_vir_N PF09610.5 ETO17168.1 - 0.018 15.0 4.4 0.036 14.0 3.0 1.5 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) LrgA PF03788.9 ETO17168.1 - 0.48 10.1 3.9 0.71 9.6 2.7 1.1 1 0 0 1 1 1 0 LrgA family MIP-T3 PF10243.4 ETO17168.1 - 0.74 8.2 63.1 0.91 7.9 43.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 eIF-4B PF06273.6 ETO17169.1 - 2.7 6.6 5.9 3.5 6.2 4.1 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B PUB PF09409.5 ETO17171.1 - 0.005 16.5 0.5 0.031 14.0 0.3 2.2 1 1 0 1 1 1 1 PUB domain Zip PF02535.17 ETO17172.1 - 0.00045 19.3 0.5 0.00052 19.1 0.3 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter CDC45 PF02724.9 ETO17172.1 - 0.004 15.2 13.8 0.0049 14.9 9.6 1.0 1 0 0 1 1 1 1 CDC45-like protein DUF2052 PF09747.4 ETO17172.1 - 0.011 15.6 15.7 0.013 15.4 10.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SR-25 PF10500.4 ETO17172.1 - 0.017 14.6 17.8 0.023 14.2 12.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CMV_1a PF12467.3 ETO17172.1 - 0.071 13.4 11.3 0.084 13.2 7.9 1.1 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family DUF572 PF04502.8 ETO17172.1 - 0.091 11.9 14.8 0.11 11.6 10.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Vfa1 PF08432.5 ETO17172.1 - 0.1 12.6 17.0 0.13 12.3 11.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TFIIF_alpha PF05793.7 ETO17172.1 - 0.11 10.8 19.3 0.13 10.5 13.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Mem_trans PF03547.13 ETO17172.1 - 0.12 10.6 1.5 0.12 10.6 1.0 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF4045 PF13254.1 ETO17172.1 - 0.27 10.4 14.7 0.32 10.2 10.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Pox_Ag35 PF03286.9 ETO17172.1 - 0.28 10.6 15.0 0.35 10.3 10.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NARP1 PF12569.3 ETO17172.1 - 0.36 9.5 14.0 0.44 9.2 9.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Lin-8 PF03353.10 ETO17172.1 - 0.4 9.9 16.7 0.51 9.5 11.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Tim54 PF11711.3 ETO17172.1 - 0.65 8.5 12.9 0.78 8.2 8.9 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Neur_chan_memb PF02932.11 ETO17172.1 - 0.72 9.6 5.7 0.9 9.3 4.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Cytomega_UL84 PF06284.6 ETO17172.1 - 0.79 8.0 9.3 1 7.7 6.5 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein SelP_N PF04592.9 ETO17172.1 - 0.8 9.0 7.8 0.98 8.7 5.4 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Plasmodium_Vir PF05795.6 ETO17172.1 - 0.82 8.8 10.2 1 8.4 7.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein MCPVI PF02993.9 ETO17172.1 - 0.87 9.6 7.4 1.1 9.3 5.1 1.1 1 0 0 1 1 1 0 Minor capsid protein VI Hid1 PF12722.2 ETO17172.1 - 1 6.9 12.7 1.2 6.7 8.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3824 PF12868.2 ETO17172.1 - 1.4 9.8 10.4 2.5 9.0 7.2 1.4 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF2201_N PF13203.1 ETO17172.1 - 1.4 8.0 10.0 1.7 7.7 6.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain SID-1_RNA_chan PF13965.1 ETO17172.1 - 1.9 6.5 4.4 2.2 6.3 3.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Sporozoite_P67 PF05642.6 ETO17172.1 - 2 6.1 13.1 2.2 6.0 9.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RR_TM4-6 PF06459.7 ETO17172.1 - 2.1 8.1 16.3 2.7 7.8 11.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1675 PF07897.6 ETO17172.1 - 2.1 8.1 11.1 2.6 7.8 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) SAPS PF04499.10 ETO17172.1 - 2.3 6.7 12.2 2.6 6.5 8.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ndc1_Nup PF09531.5 ETO17172.1 - 2.6 6.3 8.4 3.2 6.0 5.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Sec62 PF03839.11 ETO17172.1 - 2.7 7.3 11.9 3.6 6.9 8.3 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 GAGA_bind PF06217.7 ETO17172.1 - 3.2 7.6 10.9 3.9 7.3 7.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Rtf2 PF04641.7 ETO17172.1 - 4 6.5 16.8 4.9 6.2 11.6 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Ycf1 PF05758.7 ETO17172.1 - 5.9 4.4 15.0 6.2 4.3 10.4 1.0 1 0 0 1 1 1 0 Ycf1 FAM60A PF15396.1 ETO17172.1 - 7.4 6.2 10.3 9 5.9 7.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A CENP-T PF15511.1 ETO17172.1 - 7.8 5.6 20.1 9.5 5.3 13.9 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF1510 PF07423.6 ETO17172.1 - 8 5.7 27.3 11 5.3 18.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nop14 PF04147.7 ETO17172.1 - 9.6 3.9 22.5 12 3.6 15.6 1.0 1 0 0 1 1 1 0 Nop14-like family DUF508 PF04370.7 ETO17174.1 - 8.4 5.9 7.9 15 5.1 5.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) RRM_1 PF00076.17 ETO17175.1 - 3.9e-10 39.2 0.0 1.1e-09 37.7 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO17175.1 - 9.5e-10 38.3 0.0 2.2e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO17175.1 - 0.00076 19.2 0.0 0.0019 18.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_2 PF07719.12 ETO17176.1 - 0.011 15.5 2.2 1.1 9.3 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETO17176.1 - 0.017 14.6 1.9 3.2 7.5 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 ETO17176.1 - 0.018 14.6 1.7 0.39 10.3 0.2 2.3 2 0 0 2 2 2 0 TPR repeat SelP_N PF04592.9 ETO17176.1 - 0.22 10.9 3.8 0.3 10.4 2.6 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region G-alpha PF00503.15 ETO17177.1 - 9.9e-122 406.3 7.9 1.2e-121 406.0 5.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO17177.1 - 1.4e-10 40.6 0.3 1.5e-07 30.8 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 ETO17177.1 - 0.00017 22.0 0.1 0.71 10.3 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 ETO17177.1 - 0.0019 17.3 3.5 0.071 12.2 0.0 3.0 3 0 0 3 3 3 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 ETO17177.1 - 0.002 18.0 0.1 2.4 8.1 0.0 2.5 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 ETO17177.1 - 0.0092 15.4 0.1 0.021 14.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RabGAP-TBC PF00566.13 ETO17178.1 - 3e-39 134.7 5.1 3e-39 134.7 3.5 2.8 2 1 0 2 2 2 1 Rab-GTPase-TBC domain Menin PF05053.8 ETO17178.1 - 0.11 10.6 6.8 0.17 10.0 4.7 1.2 1 0 0 1 1 1 0 Menin DUF4407 PF14362.1 ETO17178.1 - 1.5 7.7 8.7 2.1 7.2 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NARP1 PF12569.3 ETO17178.1 - 8.4 5.0 18.8 5.1 5.7 10.9 1.8 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 BRICHOS PF04089.9 ETO17179.1 - 0.00074 19.3 0.3 0.0014 18.4 0.2 1.4 1 0 0 1 1 1 1 BRICHOS domain TYA PF01021.14 ETO17179.1 - 0.97 9.6 5.0 0.11 12.7 0.5 1.6 2 0 0 2 2 2 0 TYA transposon protein SAM_1 PF00536.25 ETO17180.1 - 7.8e-11 41.9 1.7 1e-10 41.6 0.3 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO17180.1 - 4.1e-10 39.3 1.0 9.5e-10 38.1 0.2 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) TACC PF05010.9 ETO17180.1 - 0.02 14.6 0.5 0.023 14.4 0.4 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) Mito_fiss_reg PF05308.6 ETO17180.1 - 0.073 12.4 1.0 0.095 12.0 0.7 1.3 1 1 0 1 1 1 0 Mitochondrial fission regulator Lipoprotein_7 PF01540.11 ETO17180.1 - 0.083 11.9 0.7 0.13 11.3 0.5 1.3 1 0 0 1 1 1 0 Adhesin lipoprotein DUF4404 PF14357.1 ETO17180.1 - 0.31 11.4 6.5 0.1 13.0 2.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) TBPIP PF07106.8 ETO17180.1 - 0.44 10.0 8.6 0.99 8.9 3.5 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Phage_Mu_Gam PF07352.7 ETO17180.1 - 1.8 8.0 6.7 6.4 6.2 0.0 2.5 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein PilO PF04350.8 ETO17180.1 - 7.9 6.3 9.2 30 4.4 3.7 2.4 3 0 0 3 3 3 0 Pilus assembly protein, PilO TPR_11 PF13414.1 ETO17182.1 - 2.1e-19 68.8 1.6 4.8e-13 48.5 0.1 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETO17182.1 - 2.3e-16 58.6 2.8 6.8e-07 28.6 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO17182.1 - 2.8e-14 51.8 1.8 4.3e-06 26.2 0.0 3.8 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO17182.1 - 1.9e-09 36.6 1.0 0.0013 18.3 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO17182.1 - 1.1e-07 32.3 0.0 0.023 15.3 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO17182.1 - 3.4e-07 30.2 1.0 9.1e-07 28.9 0.2 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO17182.1 - 2.7e-06 27.6 0.1 0.0044 17.3 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO17182.1 - 1.4e-05 25.1 0.1 0.023 15.1 0.0 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETO17182.1 - 1.5e-05 24.7 0.0 7.2e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO17182.1 - 0.00011 22.4 0.0 0.9 10.3 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO17182.1 - 0.00053 19.9 0.8 0.016 15.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO17182.1 - 0.0014 18.4 3.9 0.099 12.5 0.1 3.2 3 1 1 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.1 ETO17182.1 - 0.0016 18.3 1.1 0.031 14.2 0.1 3.1 1 1 3 4 4 4 1 Tetratricopeptide repeat YfiO PF13525.1 ETO17182.1 - 0.0054 16.2 1.6 0.0054 16.2 1.1 1.6 2 0 0 2 2 2 1 Outer membrane lipoprotein TPR_3 PF07720.7 ETO17182.1 - 0.24 11.2 1.3 2.2 8.1 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat RNA_pol_Rpb1_5 PF04998.12 ETO17182.1 - 0.45 9.7 2.7 0.69 9.1 1.8 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 AIF_C PF14721.1 ETO17183.1 - 0.066 13.4 5.5 0.083 13.1 3.8 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF3807 PF12720.2 ETO17183.1 - 0.16 12.0 8.7 0.16 12.1 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF1510 PF07423.6 ETO17183.1 - 0.19 11.0 10.1 0.2 11.0 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2058 PF09831.4 ETO17183.1 - 0.2 11.5 13.1 0.2 11.5 9.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) CDC45 PF02724.9 ETO17183.1 - 0.53 8.2 6.1 0.51 8.3 4.2 1.0 1 0 0 1 1 1 0 CDC45-like protein HSP90 PF00183.13 ETO17183.1 - 0.55 8.5 12.9 0.55 8.5 8.9 1.1 1 0 0 1 1 1 0 Hsp90 protein RR_TM4-6 PF06459.7 ETO17183.1 - 0.65 9.8 7.9 0.61 9.9 5.5 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 U79_P34 PF03064.11 ETO17183.1 - 0.77 9.2 10.9 0.84 9.1 7.6 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 PH_4 PF15404.1 ETO17183.1 - 1.2 8.6 9.4 1.4 8.4 6.5 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain DUF912 PF06024.7 ETO17183.1 - 1.4 9.0 4.9 1.7 8.7 3.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3464 PF11947.3 ETO17183.1 - 1.6 8.1 8.0 1.8 8.0 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) NYD-SP12_N PF15015.1 ETO17183.1 - 1.7 6.7 10.3 1.8 6.6 7.2 1.0 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal FAM176 PF14851.1 ETO17183.1 - 2 8.1 4.4 2.3 7.8 3.1 1.1 1 0 0 1 1 1 0 FAM176 family Peptidase_S49_N PF08496.5 ETO17183.1 - 2 8.1 12.9 2.5 7.8 9.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal HNOBA PF07701.9 ETO17183.1 - 2.2 7.4 7.7 3 6.9 5.3 1.2 1 0 0 1 1 1 0 Heme NO binding associated Vfa1 PF08432.5 ETO17183.1 - 2.8 7.9 17.6 3 7.8 12.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RP-C_C PF11800.3 ETO17183.1 - 3.9 7.1 5.6 3.9 7.1 3.9 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region GAGA_bind PF06217.7 ETO17183.1 - 4 7.3 12.5 3.8 7.3 8.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family YqfQ PF14181.1 ETO17183.1 - 6.9 6.6 13.4 7.4 6.5 9.3 1.1 1 0 0 1 1 1 0 YqfQ-like protein Vps4_C PF09336.5 ETO17184.1 - 2.4e-19 68.9 0.0 5.3e-18 64.6 0.0 2.0 2 0 0 2 2 2 2 Vps4 C terminal oligomerisation domain Kelch_1 PF01344.20 ETO17185.1 - 0.0002 20.7 4.3 0.00082 18.8 0.8 2.2 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.1 ETO17185.1 - 0.0003 20.4 0.1 0.06 13.1 0.0 2.3 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO17185.1 - 0.0016 18.3 0.5 0.0093 15.9 0.4 2.1 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.10 ETO17185.1 - 0.0023 17.6 0.4 0.032 14.0 0.2 2.3 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETO17185.1 - 0.0038 17.3 1.9 0.23 11.7 0.6 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO17185.1 - 0.014 15.5 0.1 0.071 13.3 0.0 2.2 3 0 0 3 3 3 0 Galactose oxidase, central domain Cytochrom_c3_2 PF14537.1 ETO17186.1 - 0.05 13.9 0.1 0.05 13.9 0.1 1.8 2 0 0 2 2 2 0 Cytochrome c3 Cytochrom_B562 PF07361.6 ETO17186.1 - 0.054 13.9 0.5 0.13 12.6 0.4 1.7 1 0 0 1 1 1 0 Cytochrome b562 TruB_N PF01509.13 ETO17186.1 - 0.25 11.4 2.1 4.4 7.4 0.7 2.3 2 1 0 2 2 2 0 TruB family pseudouridylate synthase (N terminal domain) SapB_1 PF05184.10 ETO17186.1 - 1.4 8.8 5.3 2.4 8.1 0.3 2.8 3 0 0 3 3 3 0 Saposin-like type B, region 1 Kelch_4 PF13418.1 ETO17187.1 - 2.6e-05 23.8 0.0 0.31 10.8 0.0 3.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO17187.1 - 2.9e-05 23.8 0.0 6.1 6.9 0.0 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 ETO17187.1 - 3.8e-05 23.6 0.5 0.2 11.8 0.0 4.6 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.10 ETO17187.1 - 0.0002 20.9 0.8 0.37 10.6 0.1 4.3 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.20 ETO17187.1 - 0.0031 17.0 1.8 2.1 7.9 0.1 4.1 5 0 0 5 5 5 1 Kelch motif Kelch_6 PF13964.1 ETO17188.1 - 5.5e-10 38.9 4.3 0.00042 20.3 0.1 4.9 4 1 1 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO17188.1 - 1.8e-08 33.7 4.6 2.7e-06 26.8 0.2 4.3 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 ETO17188.1 - 8.1e-07 28.8 4.2 0.11 12.4 0.1 4.8 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 ETO17188.1 - 2.2e-05 24.0 4.3 0.17 11.6 0.2 5.3 5 2 0 5 5 5 1 Kelch motif Kelch_4 PF13418.1 ETO17188.1 - 2.4e-05 23.9 0.4 0.063 13.0 0.1 3.8 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO17188.1 - 6.5e-05 22.9 0.2 0.00084 19.4 0.0 2.9 3 0 0 3 3 3 1 Galactose oxidase, central domain NAD_synthase PF02540.12 ETO17189.1 - 7.9e-75 250.8 0.3 1.2e-74 250.2 0.2 1.2 1 0 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.17 ETO17189.1 - 4.8e-10 39.0 0.0 7.7e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase tRNA_Me_trans PF03054.11 ETO17189.1 - 7.9e-05 21.3 0.0 0.00013 20.6 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.16 ETO17189.1 - 0.0013 18.2 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 ETO17189.1 - 0.01 15.1 0.6 0.026 13.8 0.0 2.0 3 0 0 3 3 3 0 Queuosine biosynthesis protein QueC La PF05383.12 ETO17190.1 - 9.7e-05 22.0 0.1 0.00028 20.6 0.1 1.8 1 0 0 1 1 1 1 La domain AATF-Che1 PF13339.1 ETO17190.1 - 0.17 12.0 3.6 2.1 8.5 1.0 2.1 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Cut12 PF11500.3 ETO17190.1 - 0.17 11.5 6.4 0.093 12.4 2.7 1.8 1 1 1 2 2 2 0 Spindle pole body formation-associated protein IncA PF04156.9 ETO17190.1 - 4.3 6.8 5.2 7.3 6.1 3.6 1.4 1 0 0 1 1 1 0 IncA protein RelA_SpoT PF04607.12 ETO17191.1 - 0.00036 20.5 1.1 0.00036 20.5 0.8 3.2 4 0 0 4 4 4 1 Region found in RelA / SpoT proteins BORA_N PF15280.1 ETO17191.1 - 0.069 12.4 5.5 4.4 6.5 2.1 3.1 2 1 0 2 2 2 0 Protein aurora borealis N-terminus CUE PF02845.11 ETO17192.1 - 0.013 14.9 0.1 0.07 12.6 0.0 2.2 2 0 0 2 2 2 0 CUE domain ART PF01129.13 ETO17192.1 - 0.022 13.8 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase TPR_12 PF13424.1 ETO17193.1 - 5.9e-31 106.2 9.2 1.6e-19 69.5 0.2 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO17193.1 - 8.6e-22 76.5 13.4 1.1e-07 31.3 0.7 3.7 3 0 0 3 3 3 3 TPR repeat TPR_10 PF13374.1 ETO17193.1 - 6.4e-17 60.8 2.2 1.6e-06 27.7 0.0 5.6 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO17193.1 - 1.4e-16 59.2 31.1 1.6e-08 33.7 1.9 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO17193.1 - 6.7e-14 50.6 30.6 4e-06 26.3 0.7 6.1 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO17193.1 - 3.6e-12 45.1 4.3 0.00035 20.1 0.1 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO17193.1 - 3e-11 42.2 26.0 6.8e-07 28.6 1.1 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO17193.1 - 1.7e-10 40.2 6.3 0.0047 17.0 0.0 4.4 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO17193.1 - 8.2e-08 32.2 3.9 1.5 9.7 0.0 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO17193.1 - 1.5e-07 31.9 1.7 0.14 12.8 0.0 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO17193.1 - 0.00015 21.9 5.2 2.5 8.7 0.1 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO17193.1 - 0.0055 16.8 1.0 0.0055 16.8 0.7 3.6 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 ETO17193.1 - 0.02 14.1 0.1 2.3 7.5 0.0 2.8 3 0 0 3 3 3 0 SHNi-TPR TRAP_beta PF05753.9 ETO17193.1 - 0.02 14.0 0.5 0.097 11.8 0.1 2.0 2 0 0 2 2 2 0 Translocon-associated protein beta (TRAPB) Trp_leader2 PF08056.6 ETO17193.1 - 0.055 13.4 2.3 0.087 12.8 0.6 2.2 2 0 0 2 2 1 0 Tryptophan operon leader peptide OEP PF02321.13 ETO17193.1 - 0.17 11.4 0.2 0.17 11.4 0.1 2.4 3 0 0 3 3 3 0 Outer membrane efflux protein DUF2225 PF09986.4 ETO17193.1 - 0.3 10.5 11.7 4.4 6.6 1.0 2.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) BssS PF13991.1 ETO17194.1 - 0.052 13.2 5.6 5.8 6.7 0.2 4.2 4 0 0 4 4 4 0 BssS protein family DUF3665 PF12427.3 ETO17194.1 - 0.13 11.6 0.4 0.47 9.8 0.1 2.1 2 0 0 2 2 2 0 Branched-chain amino acid aminotransferase Phage_int_SAM_2 PF12834.2 ETO17194.1 - 0.24 11.8 18.9 1.9 8.8 3.4 4.1 4 0 0 4 4 4 0 Phage integrase, N-terminal GAS PF13851.1 ETO17194.1 - 4.4 6.4 95.5 0.052 12.7 19.0 5.5 4 1 2 6 6 6 0 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 ETO17194.1 - 5.3 6.1 16.6 0.43 9.7 2.3 4.3 3 2 2 5 5 5 0 Reovirus sigma C capsid protein Peripla_BP_2 PF01497.13 ETO17194.1 - 5.8 5.9 14.4 1.1 8.3 3.2 3.6 3 1 1 4 4 4 0 Periplasmic binding protein DNA_circ_N PF07157.7 ETO17195.1 - 0.1 12.7 0.1 0.35 11.0 0.0 1.9 1 0 0 1 1 1 0 DNA circularisation protein N-terminus Copper-bind PF00127.15 ETO17196.1 - 0.018 15.2 0.3 0.034 14.3 0.1 1.6 1 1 1 2 2 2 0 Copper binding proteins, plastocyanin/azurin family GF_recep_IV PF14843.1 ETO17196.1 - 0.03 13.9 0.1 0.039 13.5 0.1 1.1 1 0 0 1 1 1 0 Growth factor receptor domain IV DUF535 PF04393.8 ETO17196.1 - 0.067 12.0 0.2 0.11 11.4 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF535) DUF1539 PF07560.6 ETO17197.1 - 0.0064 16.3 2.4 0.017 14.9 0.4 2.2 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1539) SATase_N PF06426.9 ETO17197.1 - 0.029 14.6 0.0 0.057 13.6 0.0 1.5 1 0 0 1 1 1 0 Serine acetyltransferase, N-terminal Spc24 PF08286.6 ETO17197.1 - 0.03 14.0 1.3 0.03 14.0 0.9 1.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Tropomyosin_1 PF12718.2 ETO17197.1 - 0.043 13.6 1.0 0.068 13.0 0.7 1.3 1 0 0 1 1 1 0 Tropomyosin like tRNA_NucTran2_2 PF13735.1 ETO17197.1 - 0.35 10.6 3.6 9.2 6.0 0.2 2.2 2 0 0 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative DUF964 PF06133.6 ETO17198.1 - 0.085 12.8 0.1 0.2 11.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF964) HSP70 PF00012.15 ETO17199.1 - 2.9e-05 22.1 0.0 8.6e-05 20.6 0.0 1.7 2 0 0 2 2 2 1 Hsp70 protein WD40 PF00400.27 ETO17200.1 - 1.2e-39 132.8 10.7 1.8e-12 46.6 0.2 4.6 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO17200.1 - 8.9e-05 20.8 1.3 0.061 11.4 0.0 3.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 WD40 PF00400.27 ETO17202.1 - 3.7e-10 39.2 0.0 1.5e-09 37.3 0.0 2.0 2 0 0 2 2 2 1 WD domain, G-beta repeat S1_2 PF13509.1 ETO17202.1 - 0.0067 16.3 0.0 0.044 13.7 0.0 2.2 2 0 0 2 2 2 1 S1 domain IncA PF04156.9 ETO17202.1 - 4.2 6.9 6.4 12 5.4 4.4 1.7 1 1 0 1 1 1 0 IncA protein RFC1 PF08519.7 ETO17203.1 - 0.066 12.9 0.0 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 Replication factor RFC1 C terminal domain Auxin_inducible PF02519.9 ETO17204.1 - 0.052 13.5 0.5 0.2 11.7 0.4 2.0 1 0 0 1 1 1 0 Auxin responsive protein AF-4 PF05110.8 ETO17205.1 - 0.0067 14.3 8.3 0.0086 14.0 5.7 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein SR-25 PF10500.4 ETO17205.1 - 0.31 10.4 9.5 0.45 9.9 6.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4653 PF15546.1 ETO17205.1 - 0.45 9.7 7.1 0.64 9.2 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) Na_trans_assoc PF06512.8 ETO17205.1 - 0.54 10.1 5.7 0.84 9.5 3.9 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated ABC_membrane_2 PF06472.10 ETO17206.1 - 2.3e-46 158.1 0.0 3.6e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 FGF PF00167.13 ETO17207.1 - 0.0089 15.8 0.2 0.013 15.2 0.1 1.3 1 0 0 1 1 1 1 Fibroblast growth factor Ank_2 PF12796.2 ETO17207.1 - 0.0089 16.3 0.1 0.016 15.5 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) PH PF00169.24 ETO17208.1 - 0.0029 17.7 0.4 0.0099 16.0 0.1 2.1 2 1 0 2 2 2 1 PH domain PH_3 PF14593.1 ETO17208.1 - 0.079 12.8 0.3 0.18 11.7 0.2 1.6 1 0 0 1 1 1 0 PH domain Bravo_FIGEY PF13882.1 ETO17208.1 - 5.1 8.0 7.9 0.6 11.0 0.5 2.6 2 1 1 3 3 3 0 Bravo-like intracellular region PRiA4_ORF3 PF07929.6 ETO17209.1 - 0.044 13.2 0.0 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 Plasmid pRiA4b ORF-3-like protein MSP PF01716.13 ETO17210.1 - 0.048 12.7 0.1 0.075 12.0 0.1 1.3 1 0 0 1 1 1 0 Manganese-stabilising protein / photosystem II polypeptide 6PF2K PF01591.13 ETO17211.1 - 9.1e-48 162.2 0.2 1.4e-47 161.6 0.1 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 ETO17211.1 - 2.2e-34 118.8 0.5 1.8e-32 112.6 0.0 2.3 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Val_tRNA-synt_C PF10458.4 ETO17211.1 - 0.03 14.4 0.2 0.078 13.0 0.1 1.6 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm Sec3_C PF09763.4 ETO17212.1 - 2e-09 36.1 7.5 2.2e-09 36.0 5.2 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec3 PilJ PF13675.1 ETO17212.1 - 0.065 13.5 0.1 0.1 12.9 0.1 1.3 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term HORMA PF02301.13 ETO17212.1 - 0.091 12.2 1.7 0.12 11.7 0.3 1.8 2 0 0 2 2 2 0 HORMA domain RE_Eco47II PF09553.5 ETO17212.1 - 0.092 11.8 0.2 0.23 10.5 0.0 1.6 1 1 1 2 2 2 0 Eco47II restriction endonuclease DUF2115 PF09888.4 ETO17212.1 - 0.19 11.8 2.9 0.27 11.3 2.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) MGDG_synth PF06925.6 ETO17212.1 - 0.23 11.3 1.5 0.45 10.4 1.0 1.4 1 0 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase Gemini_AL1 PF00799.15 ETO17213.1 - 0.08 12.7 0.0 12 5.7 0.0 2.4 1 1 1 2 2 2 0 Geminivirus Rep catalytic domain SNAP PF14938.1 ETO17214.1 - 1.9e-18 66.6 1.4 2.4e-18 66.3 1.0 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP CLASP_N PF12348.3 ETO17215.1 - 0.0013 18.1 0.1 0.73 9.1 0.0 2.4 2 0 0 2 2 2 2 CLASP N terminal DUF2435 PF10363.4 ETO17215.1 - 0.0034 17.2 0.0 0.15 12.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) BSMAP PF12280.3 ETO17215.1 - 0.06 13.2 3.3 0.14 12.0 2.3 1.6 1 0 0 1 1 1 0 Brain specific membrane anchored protein UVR PF02151.14 ETO17216.1 - 3.5e-08 32.7 10.4 0.00078 18.8 0.2 2.3 2 0 0 2 2 2 2 UvrB/uvrC motif LUC7 PF03194.10 ETO17216.1 - 0.052 13.0 5.0 0.079 12.4 3.5 1.3 1 0 0 1 1 1 0 LUC7 N_terminus IMD PF08397.6 ETO17216.1 - 0.076 12.3 8.5 0.14 11.4 5.9 1.4 1 0 0 1 1 1 0 IRSp53/MIM homology domain Secretin_N_2 PF07655.8 ETO17216.1 - 1.1 9.6 21.6 3.4 8.1 15.0 1.8 1 0 0 1 1 1 0 Secretin N-terminal domain BTV_NS2 PF04514.7 ETO17217.1 - 4.8 5.9 16.4 6.3 5.5 11.4 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 PA26 PF04636.8 ETO17217.1 - 8.6 4.9 8.4 10 4.6 5.8 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) IL1 PF00340.14 ETO17218.1 - 0.078 12.4 1.2 0.15 11.5 0.8 1.5 1 0 0 1 1 1 0 Interleukin-1 / 18 Selenoprotein_S PF06936.6 ETO17218.1 - 0.3 10.6 3.8 0.43 10.0 2.6 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) APG6 PF04111.7 ETO17220.1 - 0.0025 16.9 13.3 0.0025 16.9 9.2 2.0 2 0 0 2 2 2 1 Autophagy protein Apg6 DUF1843 PF08898.5 ETO17220.1 - 6.5 6.8 6.9 0.43 10.6 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) RGS PF00615.14 ETO17221.1 - 1e-06 28.8 2.1 1.4e-06 28.3 1.5 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain TPR_12 PF13424.1 ETO17222.1 - 2.2e-05 24.2 0.8 0.00021 21.1 0.5 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO17222.1 - 0.00095 18.9 0.8 0.42 10.6 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO17222.1 - 0.011 15.3 1.1 0.027 14.1 0.8 1.6 1 1 0 1 1 1 0 TPR repeat Gp23 PF07068.6 ETO17222.1 - 0.14 10.6 0.0 0.14 10.6 0.0 1.0 1 0 0 1 1 1 0 Major capsid protein Gp23 Fanconi_A PF03511.9 ETO17222.1 - 0.14 11.9 0.7 0.29 10.9 0.1 1.9 2 0 0 2 2 2 0 Fanconi anaemia group A protein TPR_1 PF00515.23 ETO17222.1 - 0.17 11.5 2.6 0.68 9.6 0.4 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF86 PF01934.12 ETO17222.1 - 0.18 11.4 0.9 0.2 11.2 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF86 PS_Dcarbxylase PF02666.10 ETO17223.1 - 3.4e-44 150.5 0.0 4.5e-43 146.9 0.0 2.4 2 1 0 2 2 2 1 Phosphatidylserine decarboxylase EF-hand_6 PF13405.1 ETO17223.1 - 2.3e-07 30.1 0.4 0.0051 16.5 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 ETO17223.1 - 0.002 18.2 0.4 0.002 18.2 0.3 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO17223.1 - 0.023 14.0 2.5 0.61 9.5 0.0 2.7 2 0 0 2 2 2 0 EF hand NESP55 PF06390.7 ETO17224.1 - 0.0054 16.1 1.7 0.0067 15.8 0.8 1.3 1 1 0 1 1 1 1 Neuroendocrine-specific golgi protein P55 (NESP55) NOA36 PF06524.7 ETO17224.1 - 0.058 12.6 11.4 0.078 12.2 7.9 1.3 1 0 0 1 1 1 0 NOA36 protein Pox_Ag35 PF03286.9 ETO17224.1 - 0.079 12.4 9.9 0.017 14.6 4.2 1.7 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Tetraspannin PF00335.15 ETO17224.1 - 0.1 11.8 7.5 0.17 11.1 4.7 1.6 1 1 1 2 2 2 0 Tetraspanin family Nop14 PF04147.7 ETO17224.1 - 1.5 6.6 12.4 1.8 6.3 8.6 1.1 1 0 0 1 1 1 0 Nop14-like family ABC2_membrane PF01061.19 ETO17225.1 - 5.6e-07 28.9 3.6 7.8e-07 28.4 2.5 1.2 1 0 0 1 1 1 1 ABC-2 type transporter TPR_12 PF13424.1 ETO17226.1 - 2.4e-39 133.1 11.4 2.4e-20 72.2 1.0 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO17226.1 - 1e-18 66.0 21.1 1.3e-07 30.8 1.3 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO17226.1 - 1.2e-17 63.3 21.4 6.8e-06 25.6 4.2 3.9 2 2 0 3 3 3 3 TPR repeat TPR_2 PF07719.12 ETO17226.1 - 1.4e-17 62.1 16.9 1e-06 28.2 0.4 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO17226.1 - 2.6e-16 58.9 0.0 0.00016 21.4 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO17226.1 - 1.5e-15 55.7 6.8 0.0002 20.8 0.1 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO17226.1 - 8.7e-10 37.6 24.8 0.0037 16.9 0.7 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO17226.1 - 3.6e-07 30.2 0.0 1 10.1 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO17226.1 - 1.3e-05 25.0 9.1 0.025 14.7 0.4 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO17226.1 - 0.00056 19.9 16.1 0.0022 18.1 3.2 3.7 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETO17226.1 - 0.0031 17.8 2.5 25 5.6 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.7 ETO17226.1 - 0.0052 16.5 1.6 0.019 14.7 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO17226.1 - 0.04 14.6 0.1 0.63 10.7 0.0 2.7 1 1 3 4 4 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO17226.1 - 0.074 12.3 0.0 0.32 10.2 0.0 2.1 1 0 0 1 1 1 0 SHNi-TPR MIT PF04212.13 ETO17226.1 - 1.7 8.5 10.3 2.7 7.9 0.3 4.0 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain WD40 PF00400.27 ETO17227.1 - 2.4e-22 77.9 15.9 2.2e-10 40.0 0.1 5.5 6 1 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO17227.1 - 2.6e-07 29.1 0.8 0.00084 17.5 0.0 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO17227.1 - 0.00034 19.5 1.6 0.057 12.1 0.2 2.8 2 1 0 2 2 2 2 Nup133 N terminal like MerR PF00376.18 ETO17227.1 - 0.11 12.0 0.0 23 4.6 0.0 3.2 3 0 0 3 3 3 0 MerR family regulatory protein MCR_C PF04609.7 ETO17228.1 - 0.078 11.7 0.2 0.095 11.4 0.1 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C HSP70 PF00012.15 ETO17229.1 - 1e-33 116.1 1.5 5.8e-20 70.7 0.1 2.2 1 1 1 2 2 2 2 Hsp70 protein Flu_C_NS2 PF03555.9 ETO17229.1 - 0.02 14.7 1.5 0.031 14.1 0.0 2.0 3 0 0 3 3 3 0 Influenza C non-structural protein (NS2) CHAT PF12770.2 ETO17229.1 - 0.082 12.0 0.1 0.099 11.7 0.1 1.1 1 0 0 1 1 1 0 CHAT domain CDC45 PF02724.9 ETO17230.1 - 0.00068 17.8 3.8 0.00075 17.6 2.6 1.0 1 0 0 1 1 1 1 CDC45-like protein DDRGK PF09756.4 ETO17230.1 - 0.037 13.4 17.5 0.049 13.0 12.1 1.1 1 0 0 1 1 1 0 DDRGK domain Velvet PF11754.3 ETO17230.1 - 0.07 12.7 0.5 0.1 12.2 0.3 1.2 1 0 0 1 1 1 0 Velvet factor Hid1 PF12722.2 ETO17230.1 - 2.4 5.7 9.8 2.6 5.6 6.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Raftlin PF15250.1 ETO17230.1 - 2.6 6.4 9.8 3 6.2 6.8 1.1 1 0 0 1 1 1 0 Raftlin Ycf1 PF05758.7 ETO17230.1 - 6.9 4.2 15.2 7.4 4.1 10.6 1.1 1 0 0 1 1 1 0 Ycf1 DUF3987 PF13148.1 ETO17230.1 - 7.6 4.9 11.9 9.6 4.6 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) LRR_1 PF00560.28 ETO17233.1 - 0.21 11.7 2.1 13 6.2 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich Repeat Chlam_PMP PF02415.12 ETO17234.1 - 1.3e-05 25.1 22.9 0.084 13.1 0.1 6.2 6 0 0 6 6 6 3 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat CX PF01705.14 ETO17234.1 - 0.14 12.1 0.4 6.3 6.8 0.1 2.9 1 1 1 2 2 2 0 CX module DUF3439 PF11921.3 ETO17235.1 - 0.0029 17.3 7.4 0.0081 15.9 5.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Mucin PF01456.12 ETO17235.1 - 0.22 11.2 18.1 0.41 10.4 12.5 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.6 ETO17235.1 - 0.37 8.6 13.5 0.58 8.0 9.4 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TPR_2 PF07719.12 ETO17237.1 - 3.2e-22 76.6 19.8 0.0032 17.2 0.3 8.7 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETO17237.1 - 1.2e-20 72.9 29.6 3.6e-08 32.9 1.7 6.6 4 2 4 8 8 8 6 TPR repeat TPR_12 PF13424.1 ETO17237.1 - 2.4e-18 65.8 19.1 1.6e-08 34.3 1.7 6.4 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO17237.1 - 5.6e-15 54.2 28.1 0.0036 16.8 0.2 9.4 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 ETO17237.1 - 4.7e-13 48.5 3.0 0.03 14.9 0.0 6.4 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETO17237.1 - 9.8e-10 37.8 19.5 0.032 14.4 0.1 7.0 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO17237.1 - 2.3e-09 37.4 5.3 0.12 12.6 0.0 5.3 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO17237.1 - 6.3e-09 36.2 2.5 0.0018 18.8 0.2 4.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO17237.1 - 1.1e-07 31.1 20.2 0.011 15.4 0.1 8.1 8 0 0 8 8 8 2 Tetratricopeptide repeat SAM_1 PF00536.25 ETO17237.1 - 3.6e-07 30.2 0.1 1.1e-06 28.7 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO17237.1 - 3.4e-06 26.8 0.2 1.3e-05 24.9 0.1 2.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) TPR_7 PF13176.1 ETO17237.1 - 5.5e-06 25.7 11.2 0.13 12.1 0.1 6.1 5 0 0 5 5 5 2 Tetratricopeptide repeat Sel1 PF08238.7 ETO17237.1 - 0.059 14.0 2.5 2.1 9.0 0.1 3.8 4 0 0 4 4 3 0 Sel1 repeat TPR_10 PF13374.1 ETO17237.1 - 0.064 13.2 6.8 4.9 7.2 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO17237.1 - 0.075 13.5 6.1 31 5.3 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat MIT PF04212.13 ETO17237.1 - 7 6.6 14.4 5.3 6.9 0.1 5.4 5 1 1 6 6 6 0 MIT (microtubule interacting and transport) domain Zip PF02535.17 ETO17239.1 - 0.13 11.2 10.9 1.7 7.6 3.1 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter Anoctamin PF04547.7 ETO17239.1 - 7 5.1 12.7 13 4.3 8.8 1.4 1 0 0 1 1 1 0 Calcium-activated chloride channel DAO PF01266.19 ETO17240.1 - 7.8e-14 51.3 0.4 9.2e-08 31.3 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETO17240.1 - 0.0008 18.3 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 ETO17240.1 - 0.0026 17.7 0.1 0.0053 16.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETO17240.1 - 0.0051 16.7 0.0 0.0085 15.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 ETO17240.1 - 0.0081 15.2 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 ETO17240.1 - 0.016 14.3 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 ETO17240.1 - 0.079 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FGE-sulfatase PF03781.11 ETO17241.1 - 1.8e-07 30.7 0.0 2.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Methyltransf_23 PF13489.1 ETO17241.1 - 1.7e-06 27.8 0.1 4.1e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO17241.1 - 2.7e-05 23.8 0.2 8.7e-05 22.1 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETO17241.1 - 4.4e-05 23.8 0.5 0.00022 21.6 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO17241.1 - 6e-05 23.4 1.3 0.00052 20.4 0.1 2.4 1 1 1 2 2 2 1 Methyltransferase domain DREV PF05219.7 ETO17241.1 - 0.0014 17.5 0.1 0.0025 16.7 0.1 1.4 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_18 PF12847.2 ETO17241.1 - 0.0018 18.8 0.0 0.0036 17.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETO17241.1 - 0.0022 18.3 0.1 0.0075 16.6 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Pkinase PF00069.20 ETO17243.1 - 7e-59 199.0 0.0 3e-58 197.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO17243.1 - 1.3e-28 99.8 0.1 6e-26 91.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 ETO17243.1 - 0.01 14.9 0.1 0.024 13.6 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO17243.1 - 0.2 11.3 0.0 4.1 7.0 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF1700 PF08006.6 ETO17246.1 - 0.15 11.3 0.7 0.29 10.4 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) RdRP PF05183.7 ETO17248.1 - 1.7e-20 73.2 0.7 1.7e-20 73.2 0.5 1.5 2 0 0 2 2 2 1 RNA dependent RNA polymerase Vfa1 PF08432.5 ETO17248.1 - 2.4 8.1 21.5 0.039 13.9 7.0 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 CTP_transf_2 PF01467.21 ETO17249.1 - 2.2e-15 57.0 0.1 3.8e-15 56.2 0.1 1.4 1 0 0 1 1 1 1 Cytidylyltransferase DUF728 PF05304.7 ETO17249.1 - 0.26 11.4 0.0 0.26 11.4 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF728) Kelch_5 PF13854.1 ETO17250.1 - 5.2e-12 45.4 0.1 0.0083 16.0 0.1 4.7 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 ETO17250.1 - 7.1e-09 35.0 0.1 0.00017 21.0 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETO17250.1 - 6.3e-08 32.2 0.1 0.00088 19.0 0.0 4.2 4 1 1 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO17250.1 - 7.3e-06 25.9 4.8 0.16 12.1 0.0 4.6 5 1 1 6 6 6 2 Kelch motif Kelch_3 PF13415.1 ETO17250.1 - 2.6e-05 24.2 0.3 0.023 14.8 0.0 4.1 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO17250.1 - 0.0014 18.2 6.0 0.056 13.2 0.1 4.4 5 1 0 5 5 5 1 Kelch motif GF_recep_IV PF14843.1 ETO17250.1 - 3.1 7.4 5.5 2.9 7.5 0.7 2.3 2 0 0 2 2 2 0 Growth factor receptor domain IV WD40 PF00400.27 ETO17251.1 - 9.4e-56 183.8 12.5 1.1e-11 44.1 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat PD40 PF07676.7 ETO17251.1 - 1.5e-07 30.9 10.3 0.0021 17.6 0.3 5.1 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat eIF2A PF08662.6 ETO17251.1 - 4.2e-06 26.5 0.0 0.00091 18.9 0.0 2.8 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 ETO17251.1 - 6.6e-05 20.9 0.1 0.0053 14.6 0.1 2.3 1 1 1 2 2 2 2 IKI3 family Cytochrom_D1 PF02239.11 ETO17251.1 - 0.00012 20.4 0.2 0.12 10.7 0.0 2.9 1 1 3 4 4 4 3 Cytochrome D1 heme domain DUF1258 PF06869.7 ETO17251.1 - 0.0014 17.7 1.3 1.2 8.2 0.0 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF1258) Ricin_B_lectin PF00652.17 ETO17251.1 - 0.013 15.4 1.4 0.024 14.6 0.1 2.0 2 1 1 3 3 3 0 Ricin-type beta-trefoil lectin domain DPPIV_N PF00930.16 ETO17251.1 - 0.078 11.5 0.0 4.6 5.7 0.0 3.0 1 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Surfac_D-trimer PF09006.6 ETO17251.1 - 0.16 11.6 0.2 0.81 9.4 0.0 2.2 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation Proteasome_A_N PF10584.4 ETO17251.1 - 0.98 8.8 3.9 9.3 5.6 0.1 2.9 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Mad3_BUB1_I PF08311.7 ETO17252.1 - 3.5e-27 94.6 7.1 3.5e-27 94.6 5.0 2.4 2 1 0 2 2 2 1 Mad3/BUB1 homology region 1 RGS PF00615.14 ETO17253.1 - 0.0064 16.5 0.5 0.012 15.6 0.3 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF2378 PF09536.5 ETO17253.1 - 0.017 14.6 0.0 0.036 13.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2378) Anillin PF08174.6 ETO17253.1 - 0.18 11.8 0.9 0.88 9.6 0.1 2.2 2 1 0 2 2 2 0 Cell division protein anillin 7TM_GPCR_Srv PF10323.4 ETO17254.1 - 0.13 11.3 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv HSBP1 PF06825.7 ETO17255.1 - 0.018 14.5 1.2 0.032 13.8 0.8 1.4 1 0 0 1 1 1 0 Heat shock factor binding protein 1 DUF912 PF06024.7 ETO17255.1 - 0.038 14.0 0.2 0.055 13.5 0.1 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) 7tm_1 PF00001.16 ETO17255.1 - 0.096 11.8 0.0 0.097 11.7 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Thioredoxin PF00085.15 ETO17257.1 - 1.7e-26 91.9 3.7 2.3e-10 40.0 0.0 3.5 2 1 1 3 3 3 3 Thioredoxin Thioredoxin_8 PF13905.1 ETO17257.1 - 4.3e-06 26.7 2.7 0.16 12.0 0.8 3.8 2 1 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 ETO17257.1 - 4.6e-06 26.8 0.5 0.00012 22.2 0.1 2.8 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 ETO17257.1 - 0.00047 20.1 1.1 3.1 7.8 0.1 3.6 2 1 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.16 ETO17257.1 - 0.021 14.5 1.2 2.7 7.7 0.0 3.0 3 0 0 3 3 3 0 AhpC/TSA family DUF4160 PF13711.1 ETO17257.1 - 0.56 10.1 3.5 0.59 10.0 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4160) RRM_1 PF00076.17 ETO17258.1 - 6.4e-13 48.1 0.1 7.3e-06 25.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO17258.1 - 9.7e-13 47.9 0.1 4.3e-06 26.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO17258.1 - 3.5e-05 23.5 0.0 3.5e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.6 ETO17258.1 - 0.00091 18.7 0.0 0.0016 17.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1866) RRM_3 PF08777.6 ETO17258.1 - 0.025 14.4 0.0 0.084 12.7 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif DUF2525 PF10733.4 ETO17258.1 - 0.13 12.0 0.1 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2525) Tox-PLDMTX PF15645.1 ETO17259.1 - 4.1 7.4 12.3 0.11 12.4 2.8 2.4 1 1 1 2 2 2 0 Dermonecrotoxin of the Papain-like fold DUF1510 PF07423.6 ETO17260.1 - 0.00019 20.8 1.6 0.00019 20.8 1.1 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1510) Neur_chan_memb PF02932.11 ETO17260.1 - 0.00031 20.7 1.3 0.00043 20.2 0.9 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF106 PF01956.11 ETO17260.1 - 0.075 12.5 0.1 0.075 12.5 0.1 2.1 2 0 0 2 2 2 0 Integral membrane protein DUF106 BCS1_N PF08740.6 ETO17260.1 - 0.5 9.9 5.5 1.6 8.3 3.8 1.8 1 1 0 1 1 1 0 BCS1 N terminal DUF4446 PF14584.1 ETO17260.1 - 0.8 9.5 5.7 0.094 12.5 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Hid1 PF12722.2 ETO17260.1 - 1.4 6.4 11.0 1.7 6.1 7.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF966 PF06136.8 ETO17260.1 - 5.9 6.2 17.8 7 5.9 12.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) WHH PF14414.1 ETO17261.1 - 0.17 11.1 1.4 0.31 10.3 1.0 1.4 1 0 0 1 1 1 0 A nuclease of the HNH/ENDO VII superfamily with conserved WHH CDC50 PF03381.10 ETO17263.1 - 1.6e-24 86.5 0.4 1.9e-24 86.2 0.3 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF2839 PF10999.3 ETO17263.1 - 0.1 12.6 3.4 0.41 10.6 1.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2839) DUF373 PF04123.8 ETO17263.1 - 0.13 11.2 1.2 0.17 10.8 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Glyco_hydro_3_C PF01915.17 ETO17264.1 - 5.5e-26 91.5 0.0 6.5e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Chal_sti_synt_N PF00195.14 ETO17264.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain UPF0126 PF03458.8 ETO17264.1 - 0.18 11.4 2.0 0.39 10.3 0.1 2.2 2 0 0 2 2 2 0 UPF0126 domain FlxA PF14282.1 ETO17265.1 - 0.056 13.4 16.0 0.067 13.1 11.1 1.0 1 0 0 1 1 1 0 FlxA-like protein DUF1003 PF06210.6 ETO17265.1 - 0.1 12.4 3.0 0.12 12.2 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) DrsE_2 PF13686.1 ETO17265.1 - 0.33 10.7 3.9 0.4 10.4 2.7 1.2 1 0 0 1 1 1 0 DsrE/DsrF/DrsH-like family DUF4577 PF15145.1 ETO17265.1 - 0.59 10.0 4.0 0.63 9.9 2.6 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4577) DUF724 PF05266.9 ETO17265.1 - 1 8.9 12.3 1.2 8.7 8.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF724) SieB PF14163.1 ETO17265.1 - 4 6.9 7.8 4.7 6.7 5.4 1.1 1 0 0 1 1 1 0 Superinfection exclusion protein B DUF3959 PF13105.1 ETO17265.1 - 5.6 6.2 12.7 6.1 6.0 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) UQ_con PF00179.21 ETO17266.1 - 3.9e-36 123.5 1.1 5.6e-36 123.0 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme PKD_channel PF08016.7 ETO17267.1 - 4.7e-11 41.7 11.6 4.7e-11 41.7 8.1 1.5 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.26 ETO17267.1 - 1.6e-05 24.2 21.2 7e-05 22.1 14.5 2.1 1 1 0 1 1 1 1 Ion transport protein Mucin PF01456.12 ETO17268.1 - 0.018 14.8 1.9 0.02 14.6 0.1 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein UCH PF00443.24 ETO17269.1 - 8e-13 48.1 0.0 8.3e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO17269.1 - 0.00057 19.4 0.0 0.00057 19.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 ETO17269.1 - 0.038 13.2 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 UPF0542 PF15086.1 ETO17270.1 - 0.00071 19.2 1.2 0.00071 19.2 0.9 2.6 2 0 0 2 2 2 1 Uncharacterised protein family UPF0542 NADH5_C PF06455.6 ETO17270.1 - 0.093 12.1 0.2 0.6 9.4 0.0 2.3 3 0 0 3 3 3 0 NADH dehydrogenase subunit 5 C-terminus Rsd_AlgQ PF04353.8 ETO17270.1 - 0.25 11.0 7.7 0.47 10.1 5.3 1.4 1 1 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Med19 PF10278.4 ETO17270.1 - 0.32 10.6 16.2 0.77 9.4 11.2 1.6 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 FAM176 PF14851.1 ETO17270.1 - 1.1 8.9 3.9 2.8 7.5 2.7 1.8 1 1 0 1 1 1 0 FAM176 family 7tm_1 PF00001.16 ETO17270.1 - 1.3 8.1 5.4 3.2 6.8 3.7 1.7 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) EphA2_TM PF14575.1 ETO17270.1 - 2.3 8.6 11.3 0.11 12.8 1.2 2.3 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Daxx PF03344.10 ETO17272.1 - 0.0074 14.8 3.2 0.0097 14.4 2.2 1.1 1 0 0 1 1 1 1 Daxx Family Sigma70_ner PF04546.8 ETO17272.1 - 0.0084 15.7 5.3 0.014 15.0 3.7 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region BTV_NS2 PF04514.7 ETO17272.1 - 0.0095 14.8 0.9 0.011 14.6 0.6 1.2 1 0 0 1 1 1 1 Bluetongue virus non-structural protein NS2 Nucleoplasmin PF03066.10 ETO17272.1 - 0.011 15.2 6.1 0.017 14.6 4.3 1.3 1 0 0 1 1 1 0 Nucleoplasmin CobT PF06213.7 ETO17272.1 - 0.012 14.7 5.9 0.016 14.3 4.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 ETO17272.1 - 0.017 13.0 2.2 0.018 12.9 1.5 1.1 1 0 0 1 1 1 0 Nop14-like family Cnd2 PF05786.9 ETO17272.1 - 0.02 13.4 1.9 0.032 12.7 1.3 1.3 1 0 0 1 1 1 0 Condensin complex subunit 2 RXT2_N PF08595.6 ETO17272.1 - 0.026 14.3 2.6 0.051 13.3 1.8 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal HSP90 PF00183.13 ETO17272.1 - 0.076 11.3 1.7 0.11 10.9 1.2 1.1 1 0 0 1 1 1 0 Hsp90 protein PBP1_TM PF14812.1 ETO17272.1 - 0.093 13.0 8.5 0.21 11.9 5.9 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.1 ETO17272.1 - 0.15 11.7 0.6 0.26 10.9 0.4 1.3 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.9 ETO17272.1 - 0.15 10.0 2.3 0.22 9.4 1.6 1.3 1 0 0 1 1 1 0 CDC45-like protein TLP-20 PF06088.6 ETO17272.1 - 0.2 11.3 2.0 0.37 10.4 1.4 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Sporozoite_P67 PF05642.6 ETO17272.1 - 0.47 8.2 2.2 0.63 7.8 1.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CENP-B_dimeris PF09026.5 ETO17272.1 - 0.99 9.6 13.4 0.24 11.6 6.7 1.9 2 1 0 2 2 2 0 Centromere protein B dimerisation domain SNF2_N PF00176.18 ETO17273.1 - 1.1e-45 155.6 0.0 2.3e-45 154.7 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain DUF2073 PF09846.4 ETO17273.1 - 0.067 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2073) RGS PF00615.14 ETO17274.1 - 1.6e-08 34.6 0.0 8e-08 32.4 0.0 1.8 1 1 0 1 1 1 1 Regulator of G protein signaling domain HEAT_2 PF13646.1 ETO17275.1 - 0.00027 21.1 0.0 0.049 13.9 0.0 2.3 2 1 0 2 2 2 1 HEAT repeats NLE PF08154.7 ETO17275.1 - 0.0073 16.2 0.2 0.98 9.4 0.0 3.1 3 1 1 4 4 4 1 NLE (NUC135) domain Proteasom_PSMB PF10508.4 ETO17275.1 - 0.029 12.6 2.1 0.23 9.6 0.1 2.1 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit DUF3810 PF12725.2 ETO17275.1 - 0.04 12.8 0.6 0.058 12.2 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) HEAT_EZ PF13513.1 ETO17275.1 - 0.062 13.8 0.0 0.63 10.6 0.0 2.4 2 1 1 3 3 3 0 HEAT-like repeat HEAT PF02985.17 ETO17275.1 - 0.069 13.2 0.0 0.41 10.8 0.0 2.3 2 0 0 2 2 2 0 HEAT repeat Baculo_PEP_C PF04513.7 ETO17275.1 - 0.069 12.9 0.2 0.93 9.3 0.1 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lip_prot_lig_C PF10437.4 ETO17275.1 - 0.079 12.6 0.4 0.61 9.7 0.0 2.4 2 1 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus HEAT_PBS PF03130.11 ETO17275.1 - 0.097 13.1 0.0 21 5.9 0.0 3.0 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Maelstrom PF13017.1 ETO17275.1 - 0.21 11.0 1.2 1.8 8.0 0.1 2.1 1 1 1 2 2 2 0 piRNA pathway germ-plasm component Complex1_LYR_1 PF13232.1 ETO17276.1 - 0.043 14.0 0.1 0.08 13.1 0.0 1.5 1 0 0 1 1 1 0 Complex1_LYR-like DUF1700 PF08006.6 ETO17277.1 - 0.00092 18.5 1.4 0.0013 18.0 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1700) DUF2101 PF09874.4 ETO17277.1 - 0.021 14.3 4.0 0.025 14.0 2.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) Phlebovirus_NSM PF07246.6 ETO17277.1 - 0.05 12.7 1.4 0.064 12.3 0.9 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Mito_carr PF00153.22 ETO17277.1 - 0.055 13.1 0.9 10 5.9 0.1 2.3 2 1 0 2 2 2 0 Mitochondrial carrier protein DDE_3 PF13358.1 ETO17278.1 - 0.00034 20.3 1.4 0.00057 19.6 0.7 1.7 1 1 1 2 2 2 1 DDE superfamily endonuclease DUF3362 PF11842.3 ETO17279.1 - 0.068 13.0 0.4 0.13 12.1 0.1 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3362) Indigoidine_A PF04227.7 ETO17280.1 - 2.1e-125 417.7 1.8 3.3e-125 417.1 1.3 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 ETO17280.1 - 7.8e-25 87.6 0.0 1.4e-24 86.7 0.0 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Arm PF00514.18 ETO17281.1 - 1.5e-21 75.3 0.5 3.1e-05 23.6 0.0 6.1 6 0 0 6 6 6 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 ETO17281.1 - 0.00012 22.2 0.0 0.3 11.3 0.0 3.2 3 0 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 ETO17281.1 - 0.001 19.5 0.0 13 6.4 0.0 4.0 4 1 0 4 4 4 1 HEAT-like repeat HEAT PF02985.17 ETO17281.1 - 0.059 13.4 0.8 46 4.4 0.0 4.1 5 0 0 5 5 5 0 HEAT repeat Peptidase_C14 PF00656.17 ETO17282.1 - 1.9e-11 44.1 0.2 3.8e-11 43.1 0.1 1.5 1 0 0 1 1 1 1 Caspase domain ABC_tran PF00005.22 ETO17282.1 - 5.9e-05 23.3 0.0 0.00026 21.3 0.0 2.1 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 ETO17282.1 - 0.00017 20.8 0.8 0.00062 18.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 ETO17282.1 - 0.0011 18.3 0.0 0.0035 16.8 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 ETO17282.1 - 0.011 15.7 0.2 0.065 13.2 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 ETO17282.1 - 0.017 14.5 0.0 0.05 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 ETO17282.1 - 0.022 15.2 0.3 0.3 11.5 0.0 3.0 2 1 0 2 2 2 0 Miro-like protein AAA_22 PF13401.1 ETO17282.1 - 0.027 14.6 0.1 0.22 11.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 ETO17282.1 - 0.046 14.0 0.0 0.046 14.0 0.0 4.6 2 2 1 3 3 2 0 AAA domain MMR_HSR1 PF01926.18 ETO17282.1 - 0.068 13.1 0.2 0.37 10.7 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase UPF0079 PF02367.12 ETO17282.1 - 0.11 12.1 1.4 0.31 10.6 0.1 2.4 2 1 1 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 ETO17282.1 - 0.12 12.2 0.1 0.35 10.7 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 ETO17282.1 - 0.25 10.9 0.1 0.66 9.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 ETO17282.1 - 0.75 10.6 0.0 0.75 10.6 0.0 4.3 3 1 0 3 3 3 0 AAA domain DUF4407 PF14362.1 ETO17283.1 - 0.064 12.1 14.8 0.094 11.6 10.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3086 PF11285.3 ETO17283.1 - 3.4 6.4 16.6 0.73 8.5 9.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3086) cNMP_binding PF00027.24 ETO17284.1 - 7.8e-07 28.8 0.0 1.4e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Nop14 PF04147.7 ETO17284.1 - 0.0076 14.2 14.1 0.0068 14.3 9.7 1.1 1 0 0 1 1 1 1 Nop14-like family NARP1 PF12569.3 ETO17284.1 - 0.13 10.9 12.0 0.15 10.7 8.3 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Zip PF02535.17 ETO17284.1 - 0.23 10.4 2.1 0.23 10.4 1.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.7 ETO17284.1 - 0.32 10.8 11.4 0.39 10.5 7.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 ETO17284.1 - 0.5 10.1 5.8 0.59 9.8 4.0 1.2 1 0 0 1 1 1 0 DDHD domain DUF1510 PF07423.6 ETO17284.1 - 0.57 9.5 17.6 0.79 9.0 12.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TFIIF_alpha PF05793.7 ETO17284.1 - 0.93 7.7 28.0 1.3 7.3 19.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.9 ETO17284.1 - 1.2 7.0 12.8 1.4 6.8 8.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Sec62 PF03839.11 ETO17284.1 - 2.8 7.2 14.9 4.1 6.7 10.3 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 HSP90 PF00183.13 ETO17284.1 - 3.9 5.7 24.0 6.1 5.1 16.6 1.3 1 0 0 1 1 1 0 Hsp90 protein Ion_trans PF00520.26 ETO17285.1 - 5.7e-25 87.7 44.2 2.7e-20 72.5 12.9 4.3 3 1 1 4 4 4 2 Ion transport protein cNMP_binding PF00027.24 ETO17285.1 - 7.6e-05 22.4 0.0 0.0002 21.1 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DEP PF00610.16 ETO17285.1 - 0.0021 17.7 0.0 0.0067 16.1 0.0 1.9 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Secretin_N_2 PF07655.8 ETO17285.1 - 0.16 12.3 19.9 0.59 10.5 13.8 2.1 1 0 0 1 1 1 0 Secretin N-terminal domain Menin PF05053.8 ETO17285.1 - 9.1 4.3 9.0 14 3.7 6.2 1.1 1 0 0 1 1 1 0 Menin DUF1336 PF07059.7 ETO17286.1 - 2e-17 63.4 0.1 4.1e-16 59.0 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1336) DUF778 PF05608.7 ETO17286.1 - 0.0092 15.9 1.5 0.034 14.1 0.3 2.0 1 1 0 2 2 2 1 Protein of unknown function (DUF778) HhH-GPD PF00730.20 ETO17286.1 - 0.068 13.4 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein DUF3439 PF11921.3 ETO17286.1 - 0.13 12.0 7.7 0.26 11.0 5.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 ETO17286.1 - 0.46 8.3 9.4 0.6 8.0 6.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Methyltransf_26 PF13659.1 ETO17287.1 - 1.1e-12 48.0 0.0 2.1e-12 47.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETO17287.1 - 6.1e-12 45.2 0.3 2.5e-09 36.7 0.1 2.4 2 0 0 2 2 2 2 Methyltransferase small domain PrmA PF06325.8 ETO17287.1 - 7.8e-12 44.9 0.3 1.6e-11 43.9 0.1 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 ETO17287.1 - 4.4e-11 42.4 0.2 1.9e-08 33.9 0.0 2.4 1 1 0 2 2 2 2 Conserved hypothetical protein 95 Methyltransf_18 PF12847.2 ETO17287.1 - 2.9e-10 40.7 0.2 5.4e-10 39.8 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO17287.1 - 1.1e-08 34.8 3.8 4.2e-08 32.9 2.6 2.2 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 ETO17287.1 - 8.7e-06 25.4 0.2 4.3e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_15 PF09445.5 ETO17287.1 - 3.7e-05 23.3 1.6 9.1e-05 22.0 1.1 1.8 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 ETO17287.1 - 4.5e-05 23.0 0.1 0.0079 15.7 0.0 2.2 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.1 ETO17287.1 - 8.6e-05 22.2 1.3 0.00029 20.5 0.9 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETO17287.1 - 9.9e-05 22.1 0.0 0.00014 21.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 ETO17287.1 - 0.00027 20.0 0.1 0.0009 18.3 0.0 1.8 1 1 1 2 2 2 1 O-methyltransferase Methyltransf_11 PF08241.7 ETO17287.1 - 0.00047 20.5 0.1 0.007 16.8 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.15 ETO17287.1 - 0.00066 18.7 0.1 0.0014 17.7 0.0 1.7 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.7 ETO17287.1 - 0.00086 19.7 0.5 0.015 15.7 0.4 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETO17287.1 - 0.0017 18.7 0.2 0.0077 16.5 0.1 2.1 1 1 0 2 2 2 1 Methyltransferase domain DNA_methylase PF00145.12 ETO17287.1 - 0.0023 17.1 1.2 0.032 13.3 0.0 2.2 1 1 1 2 2 2 1 C-5 cytosine-specific DNA methylase PCMT PF01135.14 ETO17287.1 - 0.009 15.5 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AdoMet_MTase PF07757.8 ETO17287.1 - 0.013 15.5 0.0 0.059 13.5 0.0 2.0 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase Methyltransf_4 PF02390.12 ETO17287.1 - 0.021 13.8 0.3 0.041 12.9 0.1 1.6 1 1 0 1 1 1 0 Putative methyltransferase Methyltransf_9 PF08003.6 ETO17287.1 - 0.039 12.6 0.0 0.091 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) FmrO PF07091.6 ETO17287.1 - 0.055 12.4 0.1 0.11 11.5 0.1 1.4 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_16 PF10294.4 ETO17287.1 - 0.12 11.8 1.6 0.25 10.7 0.1 2.1 2 1 0 2 2 2 0 Putative methyltransferase Peptidase_S49_N PF08496.5 ETO17287.1 - 0.17 11.6 1.6 0.27 11.0 1.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal UPF0184 PF03670.8 ETO17288.1 - 0.00021 21.3 3.0 0.017 15.2 0.3 2.7 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0184) NRN1 PF15056.1 ETO17288.1 - 0.68 9.9 4.0 0.58 10.1 0.5 2.6 2 1 0 2 2 2 0 Neuritin protein family Peptidase_M8 PF01457.11 ETO17289.1 - 0.0032 15.8 0.0 0.0036 15.6 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin DUF912 PF06024.7 ETO17289.1 - 0.0088 16.0 1.0 0.011 15.7 0.7 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Rifin_STEVOR PF02009.11 ETO17289.1 - 0.01 15.5 4.3 0.011 15.4 3.0 1.1 1 0 0 1 1 1 1 Rifin/stevor family LRRC37AB_C PF14914.1 ETO17289.1 - 0.023 14.1 2.5 0.029 13.8 1.7 1.3 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Fig1 PF12351.3 ETO17289.1 - 0.076 12.8 0.6 0.088 12.6 0.4 1.1 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 AJAP1_PANP_C PF15298.1 ETO17289.1 - 0.11 12.3 0.7 0.12 12.2 0.5 1.2 1 0 0 1 1 1 0 AJAP1/PANP C-terminus ODV-E18 PF10717.4 ETO17289.1 - 0.47 9.9 4.3 0.75 9.2 3.0 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF4519 PF15012.1 ETO17289.1 - 0.66 9.9 4.2 1.2 9.0 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) TMEM154 PF15102.1 ETO17289.1 - 8.8 6.0 10.6 12 5.6 7.4 1.4 1 1 0 1 1 1 0 TMEM154 protein family Lectin_leg-like PF03388.8 ETO17291.1 - 1.2e-14 53.9 1.2 8.8e-13 47.9 0.8 2.1 1 1 0 1 1 1 1 Legume-like lectin family Orthopox_A36R PF05950.6 ETO17292.1 - 0.09 12.6 1.7 0.1 12.5 0.1 1.8 2 0 0 2 2 2 0 Orthopoxvirus A36R protein Neur_chan_memb PF02932.11 ETO17292.1 - 0.33 10.8 3.9 0.16 11.8 0.1 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region FimP PF09766.4 ETO17293.1 - 4.4e-26 91.8 0.4 5.4e-26 91.5 0.2 1.1 1 0 0 1 1 1 1 Fms-interacting protein DUF3797 PF12677.2 ETO17294.1 - 0.06 12.9 0.6 0.11 12.1 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) Ank_5 PF13857.1 ETO17295.1 - 0.00032 20.8 0.0 0.047 13.9 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO17295.1 - 0.00034 20.8 0.1 0.00099 19.4 0.0 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO17295.1 - 0.005 17.3 0.3 0.14 12.7 0.0 2.3 1 1 0 2 2 2 1 Ankyrin repeats (many copies) DUF4220 PF13968.1 ETO17295.1 - 0.007 15.5 1.5 0.34 9.9 0.2 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4220) Ank_3 PF13606.1 ETO17295.1 - 0.0073 16.4 0.1 2 8.9 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.25 ETO17295.1 - 0.018 14.8 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat RRP14 PF15459.1 ETO17296.1 - 0.69 10.0 10.2 0.28 11.2 1.1 2.6 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 DUF2031 PF09592.5 ETO17296.1 - 6 5.9 11.1 0.46 9.5 0.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2031) CFIA_Pcf11 PF11526.3 ETO17297.1 - 0.13 12.4 0.3 0.24 11.5 0.2 1.4 1 0 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 ALMT PF11744.3 ETO17298.1 - 0.0024 16.6 0.2 0.0032 16.1 0.1 1.1 1 0 0 1 1 1 1 Aluminium activated malate transporter ORF6N PF10543.4 ETO17298.1 - 0.0094 15.9 0.6 0.021 14.8 0.4 1.5 1 0 0 1 1 1 1 ORF6N domain PspA_IM30 PF04012.7 ETO17298.1 - 0.014 14.8 0.9 0.044 13.1 0.6 1.7 1 1 0 1 1 1 0 PspA/IM30 family HTH_Crp_2 PF13545.1 ETO17298.1 - 0.022 14.5 0.0 1.8 8.4 0.0 2.4 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain DUF3698 PF12479.3 ETO17298.1 - 0.18 11.9 1.8 0.34 11.0 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3698) XkdN PF08890.6 ETO17298.1 - 0.56 9.9 6.8 0.32 10.7 3.4 1.5 2 0 0 2 2 2 0 Phage XkdN-like protein WD40 PF00400.27 ETO17299.1 - 9.4e-16 57.0 13.1 1e-06 28.3 0.4 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO17299.1 - 0.01 13.9 0.2 0.22 9.5 0.0 2.6 1 1 1 2 2 2 0 Nucleoporin Nup120/160 PD40 PF07676.7 ETO17299.1 - 0.019 14.6 4.6 1.5 8.5 0.1 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat RGS PF00615.14 ETO17301.1 - 0.046 13.8 0.0 0.17 12.0 0.0 1.8 1 1 0 1 1 1 0 Regulator of G protein signaling domain T4_Gp59_C PF08994.5 ETO17302.1 - 1.7 8.8 8.2 0.35 11.0 2.1 2.4 1 1 2 3 3 3 0 T4 gene Gp59 loader of gp41 DNA helicase C-term Oxidored_FMN PF00724.15 ETO17303.1 - 2.1e-49 168.3 0.0 2.5e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 ETO17303.1 - 0.029 13.2 0.0 0.57 8.9 0.0 2.3 1 1 1 2 2 2 0 Dihydrouridine synthase (Dus) Ceramidase PF05875.7 ETO17304.1 - 1.2e-12 47.4 17.1 1.6e-08 34.0 4.1 2.2 2 0 0 2 2 2 2 Ceramidase Inhibitor_I10 PF12559.3 ETO17305.1 - 0.0074 16.5 0.6 0.017 15.3 0.4 1.6 1 0 0 1 1 1 1 Serine endopeptidase inhibitors ZZ PF00569.12 ETO17305.1 - 0.016 14.7 4.4 0.016 14.7 3.1 1.8 2 0 0 2 2 2 0 Zinc finger, ZZ type DZR PF12773.2 ETO17305.1 - 0.05 13.4 3.0 0.092 12.5 1.6 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-UBR PF02207.15 ETO17305.1 - 1.6 8.4 7.1 2.3 7.9 2.3 2.5 1 1 1 2 2 2 0 Putative zinc finger in N-recognin (UBR box) C1_3 PF07649.7 ETO17305.1 - 5.1 7.2 12.1 0.64 10.1 5.1 2.0 2 0 0 2 2 2 0 C1-like domain MMR_HSR1 PF01926.18 ETO17306.1 - 2.2e-06 27.5 3.0 1e-05 25.4 0.1 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 ETO17306.1 - 0.0027 16.9 1.4 0.022 13.9 1.0 2.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 KSR1-SAM PF13543.1 ETO17306.1 - 0.015 15.0 2.1 0.015 15.0 1.4 4.1 3 1 1 4 4 4 0 SAM like domain present in kinase suppressor RAS 1 ABC_tran PF00005.22 ETO17306.1 - 0.017 15.4 0.1 0.017 15.4 0.1 3.0 4 1 0 4 4 4 0 ABC transporter Receptor_2B4 PF11465.3 ETO17306.1 - 0.022 14.6 2.6 0.34 10.8 0.1 2.9 2 1 1 3 3 3 0 Natural killer cell receptor 2B4 PduV-EutP PF10662.4 ETO17306.1 - 0.32 10.4 4.4 14 5.1 0.1 3.9 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation FHA PF00498.21 ETO17307.1 - 9.1e-16 57.7 0.1 4e-15 55.6 0.0 2.2 1 0 0 1 1 1 1 FHA domain DUF3899 PF13038.1 ETO17307.1 - 5.3 7.2 9.1 4.3 7.5 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) MgsA_C PF12002.3 ETO17308.1 - 1.6e-66 223.1 0.1 2.3e-66 222.6 0.0 1.2 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 ETO17308.1 - 5.2e-18 65.5 0.0 8.1e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 ETO17308.1 - 9.5e-13 47.7 0.0 2.3e-12 46.4 0.0 1.6 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 ETO17308.1 - 6.3e-07 29.1 0.1 9.3e-06 25.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETO17308.1 - 2.6e-06 27.5 0.3 0.006 16.7 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_17 PF13207.1 ETO17308.1 - 6.2e-06 27.0 0.0 1.5e-05 25.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 ETO17308.1 - 1.8e-05 24.5 0.0 0.17 11.5 0.0 2.5 1 1 1 2 2 2 2 Archaeal ATPase AAA_16 PF13191.1 ETO17308.1 - 3.4e-05 23.9 0.1 0.00045 20.2 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 ETO17308.1 - 4.5e-05 23.7 0.0 9.8e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 ETO17308.1 - 4.7e-05 23.2 0.0 0.00014 21.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 ETO17308.1 - 6.6e-05 22.1 0.1 0.023 13.8 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.10 ETO17308.1 - 0.00048 18.9 0.0 0.00071 18.3 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein Sigma54_activat PF00158.21 ETO17308.1 - 0.00049 19.6 0.0 0.07 12.6 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain SKI PF01202.17 ETO17308.1 - 0.00061 19.6 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 Shikimate kinase ResIII PF04851.10 ETO17308.1 - 0.0011 18.8 0.2 0.24 11.2 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 ETO17308.1 - 0.0016 18.6 0.0 0.0036 17.4 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 ETO17308.1 - 0.0022 16.7 0.0 0.0038 16.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Sigma54_activ_2 PF14532.1 ETO17308.1 - 0.0031 17.5 0.0 0.0064 16.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 ETO17308.1 - 0.0048 16.5 0.0 0.012 15.1 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 ETO17308.1 - 0.0051 16.4 0.0 0.64 9.6 0.0 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_19 PF13245.1 ETO17308.1 - 0.0052 16.5 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 ETO17308.1 - 0.0057 16.5 0.0 0.0098 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 ETO17308.1 - 0.0066 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 ETO17308.1 - 0.0094 16.2 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Cytidylate_kin2 PF13189.1 ETO17308.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase-like family NB-ARC PF00931.17 ETO17308.1 - 0.019 13.8 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_2 PF07724.9 ETO17308.1 - 0.019 14.8 0.0 0.068 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) cobW PF02492.14 ETO17308.1 - 0.04 13.3 0.0 8.5 5.7 0.0 2.6 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.12 ETO17308.1 - 0.046 13.1 0.0 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Viral_helicase1 PF01443.13 ETO17308.1 - 0.047 13.2 0.0 0.077 12.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 ETO17308.1 - 0.063 12.8 0.0 3.4 7.2 0.0 2.2 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.7 ETO17308.1 - 0.079 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin UPF0079 PF02367.12 ETO17308.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Fic PF02661.13 ETO17309.1 - 9.6e-14 51.8 0.1 3.6e-13 50.0 0.0 2.1 2 0 0 2 2 2 1 Fic/DOC family C5-epim_C PF06662.8 ETO17309.1 - 0.027 13.7 0.1 0.19 11.0 0.0 2.0 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus DUF4130 PF13566.1 ETO17309.1 - 0.045 13.3 0.0 0.098 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4130 ASFV_J13L PF05568.6 ETO17310.1 - 0.079 12.4 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein WD40 PF00400.27 ETO17311.1 - 3.8e-50 166.0 16.0 1.3e-12 47.0 0.5 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 ETO17311.1 - 1.5e-10 41.0 0.3 3e-06 27.0 0.0 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO17311.1 - 7.9e-06 24.2 5.0 0.2 9.7 0.0 3.8 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO17311.1 - 0.00024 19.5 0.2 0.0089 14.3 0.0 2.1 1 1 1 2 2 2 1 Cytochrome D1 heme domain Resistin PF06954.6 ETO17311.1 - 0.0011 19.1 3.3 2.2 8.6 0.1 4.3 3 2 2 5 5 5 1 Resistin Hira PF07569.6 ETO17311.1 - 0.011 14.9 0.3 0.21 10.7 0.0 2.6 2 2 0 2 2 2 0 TUP1-like enhancer of split DPPIV_N PF00930.16 ETO17311.1 - 0.045 12.3 0.7 13 4.2 0.0 3.4 2 2 2 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nbas_N PF15492.1 ETO17311.1 - 0.055 12.5 2.8 3.7 6.5 0.1 3.6 2 2 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal SGL PF08450.7 ETO17311.1 - 0.066 12.5 0.0 0.19 11.0 0.0 1.8 1 1 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region TPR_12 PF13424.1 ETO17312.1 - 4.5e-126 411.0 49.4 4.1e-18 65.0 0.4 8.6 4 2 6 10 10 10 10 Tetratricopeptide repeat TPR_1 PF00515.23 ETO17312.1 - 7.3e-60 196.3 71.1 2.4e-07 30.0 0.1 13.3 13 0 0 13 13 13 12 Tetratricopeptide repeat TPR_11 PF13414.1 ETO17312.1 - 1.7e-59 197.3 46.6 7.1e-11 41.5 2.1 8.7 5 3 3 9 9 9 9 TPR repeat TPR_2 PF07719.12 ETO17312.1 - 2.1e-56 183.3 48.7 1e-05 25.0 0.0 12.9 13 0 0 13 13 13 12 Tetratricopeptide repeat TPR_8 PF13181.1 ETO17312.1 - 9.9e-52 168.9 77.3 8.5e-07 28.3 0.4 13.6 13 0 0 13 13 13 11 Tetratricopeptide repeat TPR_7 PF13176.1 ETO17312.1 - 8.3e-51 165.8 19.3 4.3e-05 23.0 0.0 13.6 14 0 0 14 14 13 11 Tetratricopeptide repeat TPR_10 PF13374.1 ETO17312.1 - 9.8e-43 142.9 0.0 0.00091 19.0 0.0 13.4 14 0 0 14 14 14 9 Tetratricopeptide repeat TPR_14 PF13428.1 ETO17312.1 - 6.6e-21 72.9 0.0 0.44 11.3 0.0 10.9 11 1 1 12 12 11 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO17312.1 - 1.5e-20 73.2 4.6 0.091 13.4 0.8 8.5 6 3 1 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.1 ETO17312.1 - 4.8e-16 57.5 25.3 0.2 11.9 0.0 13.4 13 0 0 13 13 13 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO17312.1 - 8.6e-13 47.8 33.0 0.26 11.8 0.0 11.9 12 0 0 12 12 12 3 Tetratricopeptide repeat Apc3 PF12895.2 ETO17312.1 - 1.5e-11 44.2 34.4 0.006 16.6 0.4 7.0 4 2 3 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 ETO17312.1 - 3.3e-08 33.2 25.1 5.7 6.9 0.0 10.3 11 0 0 11 11 11 3 MIT (microtubule interacting and transport) domain TPR_19 PF14559.1 ETO17312.1 - 1e-06 28.9 10.9 0.33 11.3 0.1 7.3 4 2 3 8 8 8 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO17312.1 - 2e-05 23.7 0.0 0.22 10.8 0.0 5.5 6 0 0 6 6 6 1 SHNi-TPR Kelch_6 PF13964.1 ETO17312.1 - 0.00077 19.5 9.0 0.37 11.0 0.1 5.2 5 0 0 5 5 5 1 Kelch motif Kelch_5 PF13854.1 ETO17312.1 - 0.02 14.8 0.9 0.57 10.1 0.0 3.1 2 0 0 2 2 2 0 Kelch motif Sel1 PF08238.7 ETO17312.1 - 2.8 8.7 32.5 26 5.6 0.6 8.7 9 0 0 9 9 9 0 Sel1 repeat zf-TRAF PF02176.13 ETO17313.1 - 0.00016 22.0 0.6 0.00016 22.0 0.4 2.9 2 1 0 2 2 2 1 TRAF-type zinc finger zf-RING_2 PF13639.1 ETO17313.1 - 0.0095 15.7 2.7 0.018 14.8 1.2 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO17313.1 - 0.022 14.7 2.9 0.034 14.1 0.5 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) WHEP-TRS PF00458.15 ETO17313.1 - 0.036 13.7 1.5 0.036 13.7 1.1 1.9 2 0 0 2 2 2 0 WHEP-TRS domain MscL PF01741.13 ETO17313.1 - 0.21 11.7 4.3 0.31 11.1 0.8 2.2 1 1 1 2 2 2 0 Large-conductance mechanosensitive channel, MscL zf-C3HC4 PF00097.20 ETO17313.1 - 0.28 10.8 4.7 5.2 6.8 3.3 2.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Herpes_BLRF2 PF05812.7 ETO17313.1 - 5.3 6.8 12.2 0.48 10.2 1.7 2.7 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein L31 PF09784.4 ETO17313.1 - 7.2 6.7 7.4 7.3 6.7 1.0 2.7 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 zf-RING-like PF08746.6 ETO17313.1 - 7.9 6.5 7.8 33 4.5 5.4 2.2 1 0 0 1 1 1 0 RING-like domain UPF0556 PF10572.4 ETO17314.1 - 0.079 12.1 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0556 CSD PF00313.17 ETO17315.1 - 4.9e-08 32.6 0.1 0.074 12.8 0.0 3.2 3 0 0 3 3 3 3 'Cold-shock' DNA-binding domain DUF3637 PF12337.3 ETO17315.1 - 0.072 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3637) TMEM61 PF15105.1 ETO17316.1 - 0.12 11.9 0.0 2.1 7.8 0.0 2.1 2 0 0 2 2 2 0 TMEM61 protein family N6_N4_Mtase PF01555.13 ETO17316.1 - 0.15 11.5 1.2 0.17 11.3 0.8 1.2 1 0 0 1 1 1 0 DNA methylase FliL PF03748.9 ETO17316.1 - 1.4 9.0 11.6 1.4 8.9 0.8 3.1 2 1 1 3 3 3 0 Flagellar basal body-associated protein FliL FH2 PF02181.18 ETO17317.1 - 1.2e-36 126.4 0.0 1.4e-36 126.1 0.0 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain Ded_cyto PF06920.8 ETO17318.1 - 4.5e-25 87.9 0.4 4.5e-25 87.9 0.3 3.0 4 0 0 4 4 4 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 ETO17318.1 - 7e-21 74.7 0.1 1.7e-20 73.4 0.1 1.7 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DUF948 PF06103.6 ETO17318.1 - 0.16 11.8 1.3 1.4 8.8 0.2 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Zeta_toxin PF06414.7 ETO17320.1 - 0.0021 17.2 0.0 0.0042 16.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 ETO17320.1 - 0.11 12.5 0.0 0.31 11.0 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain Ant_C PF05586.6 ETO17321.1 - 0.014 15.8 0.1 0.014 15.8 0.1 3.2 2 1 0 3 3 3 0 Anthrax receptor C-terminus region Pkinase PF00069.20 ETO17322.1 - 4.8e-14 52.1 0.3 4.8e-14 52.1 0.2 3.2 2 1 0 2 2 2 1 Protein kinase domain DUF262 PF03235.9 ETO17324.1 - 0.6 10.0 12.7 0.77 9.6 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 RabGAP-TBC PF00566.13 ETO17325.1 - 1e-06 28.4 0.1 1.5e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Dicty_REP PF05086.7 ETO17325.1 - 6.5 4.3 18.7 1.6 6.3 5.6 2.2 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein SprA-related PF12118.3 ETO17327.1 - 0.066 12.5 15.0 0.089 12.1 10.4 1.1 1 0 0 1 1 1 0 SprA-related family Nop14 PF04147.7 ETO17327.1 - 0.43 8.4 30.1 0.7 7.7 20.9 1.3 1 0 0 1 1 1 0 Nop14-like family UPF0560 PF10577.4 ETO17327.1 - 1.6 6.9 7.8 2.1 6.5 5.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 CENP-T PF15511.1 ETO17327.1 - 1.7 7.8 19.3 2.3 7.3 13.4 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DDHD PF02862.12 ETO17327.1 - 9.3 5.9 10.7 24 4.6 6.5 2.1 2 0 0 2 2 2 0 DDHD domain BTV_NS2 PF04514.7 ETO17327.1 - 10 4.9 20.5 15 4.3 14.2 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 ABC2_membrane_3 PF12698.2 ETO17328.1 - 0.0051 15.8 0.0 0.0057 15.7 0.0 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein Neugrin PF06413.6 ETO17328.1 - 0.041 13.6 3.4 0.054 13.3 2.4 1.1 1 0 0 1 1 1 0 Neugrin Cullin PF00888.17 ETO17329.1 - 3.1e-29 101.9 6.9 9.2e-18 64.1 0.0 2.8 3 0 0 3 3 3 2 Cullin family DUF1987 PF09345.5 ETO17329.1 - 0.017 14.9 0.6 3.1 7.6 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1987) APC2 PF08672.6 ETO17329.1 - 0.056 13.6 0.1 0.15 12.3 0.1 1.8 1 0 0 1 1 1 0 Anaphase promoting complex (APC) subunit 2 Phage-A118_gp45 PF10653.4 ETO17329.1 - 0.079 12.8 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein gp45 of Bacteriophage A118 HisG PF01634.13 ETO17329.1 - 0.51 9.8 2.9 5.7 6.4 0.1 3.1 3 0 0 3 3 3 0 ATP phosphoribosyltransferase Astro_capsid PF03115.9 ETO17329.1 - 9 4.4 8.8 15 3.6 6.0 1.4 1 1 0 1 1 1 0 Astrovirus capsid protein precursor ParcG PF10274.4 ETO17330.1 - 1.4e-50 171.7 0.0 1.9e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 Parkin co-regulated protein DUF2201_N PF13203.1 ETO17331.1 - 0.00011 21.4 3.4 0.0014 17.9 0.9 2.1 2 0 0 2 2 2 1 Putative metallopeptidase domain CPSF100_C PF13299.1 ETO17331.1 - 0.063 13.4 7.0 0.22 11.7 1.8 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF788 PF05620.6 ETO17331.1 - 0.17 11.7 0.1 0.17 11.7 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF788) Zip PF02535.17 ETO17331.1 - 0.24 10.3 2.5 1.5 7.7 0.9 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter DUF912 PF06024.7 ETO17331.1 - 0.32 11.0 5.3 3.5 7.7 1.1 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) AIF_C PF14721.1 ETO17331.1 - 6.2 7.0 8.3 3.8 7.7 0.5 2.4 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Mss4 PF04421.8 ETO17331.1 - 7.1 6.5 7.1 2.7 7.8 0.2 2.9 3 0 0 3 3 3 0 Mss4 protein Vfa1 PF08432.5 ETO17332.1 - 2.4 8.1 9.9 3.4 7.6 6.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FH2 PF02181.18 ETO17333.1 - 7.2e-48 163.3 0.2 8.4e-48 163.1 0.1 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain XK-related PF09815.4 ETO17334.1 - 5.1e-09 35.5 6.5 5.1e-09 35.5 4.5 1.9 1 1 0 2 2 2 1 XK-related protein WD40 PF00400.27 ETO17335.1 - 1.8e-45 151.2 5.4 7.9e-09 35.0 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO17335.1 - 1.5e-07 31.2 2.2 0.00051 19.8 0.0 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO17335.1 - 8.5e-06 25.3 1.4 2.5 7.8 0.0 4.5 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO17335.1 - 5.7e-05 21.4 4.2 1.4 6.9 0.0 4.6 1 1 3 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO17335.1 - 0.00011 21.0 4.7 0.61 8.7 0.0 3.1 1 1 1 2 2 2 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO17335.1 - 0.0004 18.7 0.1 0.023 12.9 0.0 2.5 1 1 2 4 4 4 2 Cytochrome D1 heme domain Resistin PF06954.6 ETO17335.1 - 0.002 18.3 0.0 2.5 8.4 0.0 2.9 2 1 1 3 3 3 2 Resistin Hira PF07569.6 ETO17335.1 - 0.0023 17.1 0.0 0.034 13.3 0.0 2.5 2 1 1 3 3 3 1 TUP1-like enhancer of split DPPIV_N PF00930.16 ETO17335.1 - 0.014 14.0 0.1 3.1 6.2 0.0 3.3 2 1 1 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Proteasome_A_N PF10584.4 ETO17335.1 - 0.12 11.7 6.0 14 5.0 0.2 3.9 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Kelch_6 PF13964.1 ETO17336.1 - 0.00023 21.2 4.1 6.2 7.1 0.2 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO17336.1 - 0.00093 19.0 0.6 0.073 13.0 0.4 3.7 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 ETO17336.1 - 0.0048 16.4 6.0 2.1 7.9 0.4 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 ETO17336.1 - 0.14 11.9 4.4 15 5.4 0.1 4.2 5 1 0 5 5 5 0 Galactose oxidase, central domain Ras PF00071.17 ETO17337.1 - 0.00035 19.9 0.0 0.00063 19.1 0.0 1.5 1 0 0 1 1 1 1 Ras family FKBP_C PF00254.23 ETO17338.1 - 2.2e-11 43.5 0.0 7.1e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF2532 PF10811.3 ETO17339.1 - 0.034 13.9 4.6 0.048 13.4 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2532) DUF3470 PF11953.3 ETO17339.1 - 0.037 13.6 0.1 0.079 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3470) DUF4275 PF14101.1 ETO17339.1 - 0.082 12.9 2.0 0.11 12.5 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4275) DUF1168 PF06658.7 ETO17339.1 - 0.76 9.2 11.3 1 8.8 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) DUF1312 PF07009.6 ETO17339.1 - 2 8.2 6.1 4.6 7.1 4.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1312) ArfGap PF01412.13 ETO17340.1 - 2.9e-09 36.7 2.2 3.3e-09 36.5 0.0 2.1 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf PH PF00169.24 ETO17340.1 - 0.0036 17.4 2.6 0.012 15.7 1.8 1.9 1 1 0 1 1 1 1 PH domain Senescence PF06911.7 ETO17342.1 - 0.036 13.7 0.1 0.049 13.3 0.1 1.2 1 0 0 1 1 1 0 Senescence-associated protein MT0933_antitox PF14013.1 ETO17342.1 - 0.63 10.1 4.9 1.1 9.3 3.4 1.4 1 0 0 1 1 1 0 MT0933-like antitoxin protein CAP_GLY PF01302.20 ETO17343.1 - 1.2e-07 31.3 0.9 0.0097 15.5 0.1 2.6 2 1 0 2 2 2 2 CAP-Gly domain cNMP_binding PF00027.24 ETO17344.1 - 3.7e-47 158.0 4.6 5.4e-17 61.3 0.0 5.1 4 2 0 4 4 4 3 Cyclic nucleotide-binding domain DUF2371 PF10177.4 ETO17345.1 - 1.3 8.9 4.2 22 4.9 0.2 3.1 2 1 1 3 3 3 0 Uncharacterised conserved protein (DUF2371) Kei1 PF08552.6 ETO17346.1 - 0.0053 16.4 0.2 0.0063 16.1 0.1 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Mito_fiss_reg PF05308.6 ETO17347.1 - 0.0079 15.5 1.7 0.012 15.0 1.2 1.3 1 0 0 1 1 1 1 Mitochondrial fission regulator CAP_N PF01213.14 ETO17347.1 - 0.25 10.5 1.6 0.36 10.0 1.1 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Sec10 PF07393.6 ETO17349.1 - 9.8e-23 80.2 1.2 1.1e-22 80.1 0.9 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 DUF4208 PF13907.1 ETO17349.1 - 0.16 12.1 1.3 6.1 7.1 0.0 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4208) TPR_11 PF13414.1 ETO17350.1 - 7.6e-07 28.6 3.9 5.9e-06 25.8 0.9 2.4 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 ETO17350.1 - 8.1e-07 28.4 6.0 0.0064 16.3 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO17350.1 - 8.3e-06 25.6 6.4 0.0026 17.6 3.2 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat MIP-T3 PF10243.4 ETO17350.1 - 1.2e-05 24.0 2.8 1.2e-05 24.0 1.9 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 TPR_1 PF00515.23 ETO17350.1 - 5.2e-05 22.6 7.2 0.047 13.3 0.0 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO17350.1 - 0.0011 18.5 1.0 1.1 9.2 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETO17350.1 - 0.0019 18.0 0.3 0.008 16.0 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat Spore_coat_CotO PF14153.1 ETO17350.1 - 0.0022 17.4 6.6 0.0028 17.1 4.6 1.3 1 0 0 1 1 1 1 Spore coat protein CotO Apc3 PF12895.2 ETO17350.1 - 0.0054 16.8 2.7 0.2 11.8 0.7 2.6 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Ycf1 PF05758.7 ETO17350.1 - 0.0096 13.6 4.6 0.0099 13.6 3.2 1.1 1 0 0 1 1 1 1 Ycf1 Caldesmon PF02029.10 ETO17350.1 - 0.011 14.1 10.1 0.012 14.0 7.0 1.2 1 0 0 1 1 1 0 Caldesmon TPR_16 PF13432.1 ETO17350.1 - 0.042 14.5 0.7 3.5 8.4 0.3 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat Raftlin PF15250.1 ETO17350.1 - 0.048 12.1 7.3 0.063 11.7 5.1 1.3 1 0 0 1 1 1 0 Raftlin FSIP1 PF15554.1 ETO17350.1 - 0.049 12.4 20.8 0.12 11.2 14.4 1.6 1 1 0 1 1 1 0 FSIP1 family CDC45 PF02724.9 ETO17350.1 - 0.085 10.8 10.9 0.1 10.6 7.6 1.2 1 0 0 1 1 1 0 CDC45-like protein TPR_8 PF13181.1 ETO17350.1 - 0.16 11.7 2.9 1.9 8.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4045 PF13254.1 ETO17350.1 - 0.26 10.5 10.0 0.35 10.0 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Daxx PF03344.10 ETO17350.1 - 0.28 9.6 18.9 0.37 9.2 13.1 1.1 1 0 0 1 1 1 0 Daxx Family Trypan_PARP PF05887.6 ETO17350.1 - 0.64 9.8 11.9 0.96 9.2 8.2 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Otopetrin PF03189.8 ETO17350.1 - 0.85 8.5 5.4 1 8.2 3.8 1.2 1 0 0 1 1 1 0 Otopetrin CDK5_activator PF03261.10 ETO17350.1 - 1.5 8.1 6.6 2 7.6 4.6 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DDRGK PF09756.4 ETO17350.1 - 3.5 6.9 17.2 6.3 6.1 12.0 1.4 1 0 0 1 1 1 0 DDRGK domain DUF1510 PF07423.6 ETO17350.1 - 6.8 5.9 20.3 11 5.3 14.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TPR_11 PF13414.1 ETO17351.1 - 1.5e-08 34.1 1.0 1.5e-08 34.1 0.7 1.7 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 ETO17351.1 - 1.3e-06 28.2 1.0 1.3e-06 28.2 0.7 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO17351.1 - 1.7e-06 27.3 7.3 5.2e-06 25.8 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO17351.1 - 3.1e-06 26.6 3.6 3.1e-05 23.5 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO17351.1 - 3.9e-06 27.3 0.4 6.7e-06 26.6 0.3 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO17351.1 - 8.9e-06 25.9 0.6 0.041 14.5 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO17351.1 - 1.1e-05 25.6 1.4 2.5e-05 24.5 0.4 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO17351.1 - 1.8e-05 24.2 0.1 0.001 18.7 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO17351.1 - 0.0054 17.1 0.8 2.2 8.9 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETO17351.1 - 0.06 13.2 0.3 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETO17351.1 - 0.07 12.9 0.3 18 5.4 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat Apc3 PF12895.2 ETO17351.1 - 0.21 11.7 8.3 0.3 11.2 2.3 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 WD40 PF00400.27 ETO17352.1 - 0.0056 16.5 4.9 0.014 15.2 3.4 1.7 1 0 0 1 1 1 1 WD domain, G-beta repeat Tom22 PF04281.8 ETO17352.1 - 0.78 9.2 7.7 1.9 8.0 5.3 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Helicase_C PF00271.26 ETO17353.1 - 8.5e-29 99.2 0.0 1.6e-28 98.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETO17353.1 - 2e-16 59.9 0.0 1.5e-14 53.8 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C_2 PF13307.1 ETO17353.1 - 0.00021 21.2 0.0 0.00036 20.5 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain zf-CCHC PF00098.18 ETO17353.1 - 0.028 14.3 1.4 0.028 14.3 1.0 2.2 2 0 0 2 2 2 0 Zinc knuckle DUF1253 PF06862.7 ETO17353.1 - 0.087 11.2 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) zf-CCHC_4 PF14392.1 ETO17353.1 - 0.16 11.6 0.7 0.37 10.4 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle rpo132 PF12415.3 ETO17353.1 - 0.17 10.8 1.5 0.55 9.2 0.1 2.3 2 0 0 2 2 2 0 Poxvirus DNA dependent RNA polymerase SAM_1 PF00536.25 ETO17354.1 - 0.014 15.5 1.2 13 6.0 0.0 3.6 4 0 0 4 4 4 0 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO17354.1 - 0.037 13.8 0.6 11 5.9 0.0 3.3 4 0 0 4 4 4 0 SAM domain (Sterile alpha motif) PIG-S PF10510.4 ETO17354.1 - 0.063 11.9 3.5 0.083 11.5 2.5 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein TINF2_N PF14973.1 ETO17354.1 - 0.1 12.7 4.4 0.26 11.4 1.2 2.5 2 1 1 3 3 3 0 TERF1-interacting nuclear factor 2 N-terminus PG_binding_2 PF08823.6 ETO17354.1 - 0.14 12.2 1.5 2.4 8.3 0.1 3.6 4 1 0 4 4 4 0 Putative peptidoglycan binding domain DUF4319 PF14203.1 ETO17355.1 - 0.16 11.5 0.7 1.7 8.2 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4319) U-box PF04564.10 ETO17356.1 - 8.1e-13 48.1 0.1 1.5e-12 47.2 0.1 1.5 1 0 0 1 1 1 1 U-box domain EF-hand_4 PF12763.2 ETO17356.1 - 0.1 12.3 0.4 0.18 11.5 0.3 1.4 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand TPR_12 PF13424.1 ETO17357.1 - 2.1e-05 24.3 0.0 3.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO17357.1 - 0.003 17.3 0.0 0.0078 16.0 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO17357.1 - 0.018 14.7 0.2 0.018 14.7 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETO17357.1 - 0.023 14.2 0.1 0.066 12.8 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 ETO17357.1 - 0.035 13.7 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 TPR repeat s48_45 PF07422.8 ETO17357.1 - 0.26 11.3 6.8 0.46 10.5 4.7 1.6 1 1 0 1 1 1 0 Sexual stage antigen s48/45 domain Sec7 PF01369.15 ETO17358.1 - 4e-44 150.5 8.4 1.1e-43 149.1 5.4 2.1 1 1 1 2 2 2 1 Sec7 domain DUF1981 PF09324.5 ETO17358.1 - 1.4e-19 69.3 2.6 5.1e-19 67.5 1.8 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1981) cNMP_binding PF00027.24 ETO17359.1 - 4.9e-06 26.2 0.1 6.8e-06 25.8 0.1 1.4 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain Imm39 PF15600.1 ETO17359.1 - 0.032 14.0 1.2 0.045 13.6 0.8 1.4 1 0 0 1 1 1 0 Immunity protein 39 Baculo_FP PF03258.9 ETO17359.1 - 0.3 10.1 4.8 0.052 12.6 0.4 1.8 2 0 0 2 2 2 0 Baculovirus FP protein HSP70 PF00012.15 ETO17361.1 - 1.8e-155 518.2 0.7 2.3e-155 517.9 0.5 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 ETO17361.1 - 1.1e-05 24.1 0.0 3.5e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.11 ETO17361.1 - 0.0014 18.3 0.0 0.0029 17.2 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FlxA PF14282.1 ETO17361.1 - 3.7 7.5 20.7 0.29 11.0 8.5 2.2 1 1 1 2 2 2 0 FlxA-like protein Siah-Interact_N PF09032.6 ETO17361.1 - 5.1 7.2 12.0 0.22 11.6 3.3 2.5 3 0 0 3 3 3 0 Siah interacting protein, N terminal WD40 PF00400.27 ETO17362.1 - 7.3e-34 114.4 10.5 1.5e-11 43.6 0.1 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO17362.1 - 7.2e-07 27.7 1.4 0.0018 16.4 0.1 3.0 1 1 1 3 3 3 3 Nucleoporin Nup120/160 HARP PF07443.8 ETO17362.1 - 0.087 12.2 0.0 0.84 9.0 0.0 2.2 2 0 0 2 2 2 0 HepA-related protein (HARP) DUF2373 PF10180.4 ETO17362.1 - 1.9 8.0 5.3 3.2 7.3 0.1 2.7 2 1 0 3 3 3 0 Uncharacterised conserved protein (DUF2373) FMN_red PF03358.10 ETO17363.1 - 1.7e-14 53.5 0.0 2.2e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 ETO17363.1 - 0.0015 18.1 0.0 0.0023 17.4 0.0 1.3 1 1 0 1 1 1 1 Flavodoxin-like fold Adenylsucc_synt PF00709.16 ETO17364.1 - 1.9e-71 240.9 0.0 6.9e-71 239.1 0.0 1.7 1 1 0 1 1 1 1 Adenylosuccinate synthetase Fijivirus_P9-2 PF06837.6 ETO17364.1 - 0.033 13.3 3.0 0.053 12.6 2.1 1.2 1 0 0 1 1 1 0 Fijivirus P9-2 protein tRNA-synt_2 PF00152.15 ETO17365.1 - 2.6e-26 92.2 0.0 3e-26 91.9 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Ank_2 PF12796.2 ETO17367.1 - 2.6e-07 30.8 0.4 2.2e-05 24.7 0.2 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO17367.1 - 0.0005 19.7 0.1 0.85 9.5 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 ETO17367.1 - 0.001 19.5 0.0 0.012 16.1 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO17367.1 - 0.032 14.4 0.0 2 8.7 0.0 2.9 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO17367.1 - 0.046 13.9 0.0 36 5.0 0.0 3.6 3 0 0 3 3 3 0 Ankyrin repeat ABC2_membrane PF01061.19 ETO17369.1 - 2.7e-41 141.0 14.8 3.4e-41 140.7 10.2 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 ETO17369.1 - 0.0002 20.5 18.2 0.00035 19.7 12.6 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein Nucleoside_tran PF01733.13 ETO17370.1 - 3.6e-16 59.2 12.1 3.6e-16 59.2 8.4 1.7 2 0 0 2 2 2 1 Nucleoside transporter Jnk-SapK_ap_N PF09744.4 ETO17370.1 - 0.02 14.8 4.6 0.21 11.5 0.2 2.5 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 Shugoshin_N PF07558.6 ETO17370.1 - 0.26 11.0 2.7 0.19 11.4 0.5 1.9 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region IZUMO PF15005.1 ETO17370.1 - 0.45 10.5 4.2 11 6.0 0.7 2.2 2 0 0 2 2 2 0 Izumo sperm-egg fusion Cast PF10174.4 ETO17370.1 - 1 7.3 12.0 0.24 9.4 1.0 2.1 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone DUF1640 PF07798.6 ETO17370.1 - 5 7.1 8.9 23 4.9 6.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) SAM_2 PF07647.12 ETO17371.1 - 2e-13 49.9 0.0 3.6e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO17371.1 - 1e-10 41.5 0.0 2e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 ETO17371.1 - 0.0072 16.0 0.2 0.016 14.9 0.0 1.7 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain Abhydrolase_6 PF12697.2 ETO17372.1 - 1.8e-16 60.7 0.0 3.2e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETO17372.1 - 3e-12 46.4 0.0 8.3e-07 28.8 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETO17372.1 - 3.6e-07 29.9 0.0 6.5e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DUF1100 PF06500.6 ETO17372.1 - 7.1e-05 21.5 0.0 0.00011 20.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.16 ETO17372.1 - 0.00031 20.0 0.0 0.044 13.0 0.0 3.2 3 1 0 3 3 3 1 Prolyl oligopeptidase family PAF-AH_p_II PF03403.8 ETO17372.1 - 0.0012 17.2 0.0 0.0021 16.4 0.0 1.4 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II AXE1 PF05448.7 ETO17372.1 - 0.02 13.3 0.2 8.5 4.7 0.0 3.3 3 1 0 3 3 3 0 Acetyl xylan esterase (AXE1) Haemadin PF09065.5 ETO17372.1 - 0.097 12.2 0.1 0.21 11.1 0.1 1.6 1 0 0 1 1 1 0 Haemadin DUF2048 PF09752.4 ETO17372.1 - 0.12 11.2 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) TPR_12 PF13424.1 ETO17374.1 - 1.3e-12 47.4 3.3 5.9e-08 32.5 0.0 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO17374.1 - 8.3e-10 37.7 6.1 0.0061 16.2 0.0 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO17374.1 - 7e-09 34.9 8.8 0.045 13.6 0.1 4.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO17374.1 - 2.2e-08 33.6 9.4 3.6e-05 23.3 0.1 3.8 3 1 1 4 4 4 3 TPR repeat TPR_8 PF13181.1 ETO17374.1 - 7.6e-08 31.6 11.6 0.09 12.6 0.1 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO17374.1 - 9.1e-05 21.9 13.6 0.054 13.1 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO17374.1 - 0.00022 21.0 0.1 7.1 6.7 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO17374.1 - 0.042 14.3 1.9 0.54 10.8 0.1 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 ETO17374.1 - 0.9 9.4 10.6 27 4.7 2.2 4.5 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain Pkinase PF00069.20 ETO17375.1 - 1.9e-50 171.4 0.3 4.7e-50 170.1 0.2 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO17375.1 - 1.1e-20 73.8 0.0 1.9e-20 73.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO17375.1 - 3.9e-05 22.8 0.0 7.3e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO17375.1 - 5.9e-05 22.9 0.1 0.0047 16.6 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 ETO17375.1 - 0.00065 18.7 0.0 0.0015 17.5 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 ETO17375.1 - 0.026 13.3 0.0 0.16 10.7 0.0 2.0 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase WD40 PF00400.27 ETO17376.1 - 6.9e-22 76.4 19.3 1.4e-06 27.9 0.7 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 ETO17376.1 - 1.9e-06 27.6 0.7 8e-06 25.7 0.1 2.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A RNA_pol_Rpc82 PF05645.8 ETO17377.1 - 0.01 15.4 3.1 0.011 15.2 2.1 1.2 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 RLL PF10036.4 ETO17377.1 - 0.089 12.2 5.8 0.12 11.7 4.0 1.2 1 0 0 1 1 1 0 Putative carnitine deficiency-associated protein FadA PF09403.5 ETO17377.1 - 0.1 12.5 6.3 0.19 11.7 4.4 1.4 1 0 0 1 1 1 0 Adhesion protein FadA AATF-Che1 PF13339.1 ETO17377.1 - 0.29 11.2 9.5 0.54 10.4 6.6 1.4 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor SSP160 PF06933.6 ETO17378.1 - 0.22 9.4 11.0 0.31 8.9 7.6 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 ETO17378.1 - 0.39 10.4 3.2 0.82 9.4 2.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) VASP_tetra PF08776.6 ETO17378.1 - 1.1 8.6 16.8 0.11 11.8 2.0 4.1 4 1 1 5 5 5 0 VASP tetramerisation domain DUF676 PF05057.9 ETO17378.1 - 1.2 8.3 5.8 0.55 9.4 2.1 1.8 2 0 0 2 2 2 0 Putative serine esterase (DUF676) DUF4206 PF13901.1 ETO17378.1 - 3.9 6.9 9.7 3.9 6.9 2.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4206) DUF1168 PF06658.7 ETO17379.1 - 2.4 7.6 24.9 2.8 7.4 17.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) SART-1 PF03343.8 ETO17379.1 - 2.8 6.1 25.7 2.9 6.1 17.8 1.0 1 0 0 1 1 1 0 SART-1 family Kinesin PF00225.18 ETO17381.1 - 5.9e-05 21.9 0.2 0.00011 20.9 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain Atg14 PF10186.4 ETO17381.1 - 0.023 13.6 0.7 0.023 13.6 0.5 1.6 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 AKNA PF12443.3 ETO17381.1 - 0.038 13.9 0.3 0.038 13.9 0.2 1.8 2 0 0 2 2 2 0 AT-hook-containing transcription factor FlxA PF14282.1 ETO17381.1 - 0.061 13.2 8.0 0.59 10.1 1.6 2.2 1 1 1 2 2 2 0 FlxA-like protein Tropomyosin_1 PF12718.2 ETO17381.1 - 0.079 12.8 0.4 0.079 12.8 0.3 1.9 2 0 0 2 2 2 0 Tropomyosin like Peptidase_M3_N PF08439.5 ETO17381.1 - 0.19 11.8 2.0 1.5 8.9 0.2 2.6 3 0 0 3 3 3 0 Oligopeptidase F RGS PF00615.14 ETO17382.1 - 7e-12 45.4 1.8 1.3e-11 44.6 1.2 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF2207 PF09972.4 ETO17382.1 - 6.1 5.3 9.5 5 5.5 0.3 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) TPR_11 PF13414.1 ETO17383.1 - 5.4e-24 83.6 14.8 8.8e-10 38.0 0.4 4.5 3 1 2 5 5 5 5 TPR repeat TPR_1 PF00515.23 ETO17383.1 - 8.5e-18 63.1 9.7 2e-05 24.0 0.4 7.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO17383.1 - 1e-17 62.5 10.2 0.00083 19.0 0.2 7.0 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETO17383.1 - 2e-16 58.7 6.6 0.019 15.1 0.1 6.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO17383.1 - 3.7e-15 56.1 0.2 0.00025 21.6 0.2 5.1 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO17383.1 - 5.2e-14 51.4 0.0 0.029 14.9 0.0 4.6 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.1 ETO17383.1 - 1.2e-12 47.9 0.9 1.7e-05 25.0 0.2 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO17383.1 - 7.5e-11 40.9 1.2 0.27 11.1 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 ETO17383.1 - 1.7e-08 34.2 5.8 0.00036 20.4 0.1 5.0 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO17383.1 - 1.1e-05 25.5 0.3 0.088 13.3 0.0 5.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO17383.1 - 2.6e-05 23.6 5.3 0.031 14.0 0.4 5.9 8 0 0 8 8 7 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO17383.1 - 0.00094 19.2 8.8 0.37 10.9 0.9 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 ETO17383.1 - 0.0041 16.9 0.0 0.43 10.4 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETO17383.1 - 0.018 14.9 3.2 11 6.0 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Ribosomal_L22e PF01776.12 ETO17384.1 - 6.3e-15 55.1 0.4 6.3e-15 55.1 0.3 1.6 2 0 0 2 2 2 1 Ribosomal L22e protein family Lin-8 PF03353.10 ETO17384.1 - 0.06 12.6 10.1 0.079 12.2 7.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CDC27 PF09507.5 ETO17384.1 - 0.24 10.5 29.9 0.29 10.2 20.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SPATIAL PF15256.1 ETO17384.1 - 1.3 9.0 10.5 2.1 8.3 7.3 1.3 1 0 0 1 1 1 0 SPATIAL MIP-T3 PF10243.4 ETO17384.1 - 5.2 5.4 31.6 5.6 5.3 21.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 WD40 PF00400.27 ETO17385.1 - 1.5e-24 84.8 10.7 4.6e-09 35.8 0.3 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO17385.1 - 5.9e-05 21.3 0.5 0.015 13.4 0.1 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO17385.1 - 0.0022 17.7 4.9 0.093 12.4 1.6 2.5 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Thermopsin PF05317.6 ETO17385.1 - 0.019 13.9 0.7 0.019 13.9 0.5 1.8 2 0 0 2 2 2 0 Thermopsin Ank_2 PF12796.2 ETO17386.1 - 1.5e-05 25.2 0.0 1.9e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO17386.1 - 6.4e-05 23.3 0.0 0.00013 22.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO17386.1 - 0.0017 18.5 0.0 0.0044 17.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO17386.1 - 0.0037 17.3 0.0 0.036 14.2 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat DUF258 PF03193.11 ETO17386.1 - 0.04 13.1 0.4 2.3 7.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ResIII PF04851.10 ETO17386.1 - 0.4 10.4 3.0 8.4 6.1 0.1 2.1 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit TMEM154 PF15102.1 ETO17388.1 - 0.075 12.7 0.0 0.075 12.7 0.0 2.9 3 0 0 3 3 3 0 TMEM154 protein family RRP14 PF15459.1 ETO17388.1 - 0.078 13.0 0.6 0.078 13.0 0.4 3.2 3 0 0 3 3 3 0 60S ribosome biogenesis protein Rrp14 Conotoxin PF02950.12 ETO17388.1 - 7 7.5 8.0 13 6.6 0.1 2.7 2 1 1 3 3 3 0 Conotoxin Menin PF05053.8 ETO17389.1 - 0.57 8.2 2.8 0.68 8.0 1.9 1.1 1 0 0 1 1 1 0 Menin DUF4603 PF15376.1 ETO17390.1 - 0.051 10.7 10.8 0.068 10.3 7.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Cellulose_synt PF03552.9 ETO17390.1 - 0.12 10.6 6.3 0.15 10.2 4.4 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF1510 PF07423.6 ETO17390.1 - 0.44 9.8 18.3 0.85 8.9 12.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FAM60A PF15396.1 ETO17390.1 - 1.4 8.6 9.1 2.5 7.7 6.3 1.4 1 0 0 1 1 1 0 Protein Family FAM60A Sec62 PF03839.11 ETO17390.1 - 5.8 6.2 11.0 11 5.3 7.6 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 DUF1034 PF06280.7 ETO17391.1 - 0.00044 20.6 1.7 0.054 13.8 0.4 2.7 2 0 0 2 2 2 1 Fn3-like domain (DUF1034) zf-Di19 PF05605.7 ETO17391.1 - 0.0078 16.3 4.3 0.13 12.4 0.5 2.7 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding Mur_ligase PF01225.20 ETO17391.1 - 0.094 12.7 0.1 0.29 11.2 0.1 1.8 1 0 0 1 1 1 0 Mur ligase family, catalytic domain Sigma70_ner PF04546.8 ETO17391.1 - 0.55 9.8 16.2 0.068 12.7 4.1 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region zf-H2C2_2 PF13465.1 ETO17391.1 - 0.59 10.5 5.9 2.3 8.6 1.1 2.8 2 0 0 2 2 2 0 Zinc-finger double domain IncA PF04156.9 ETO17392.1 - 0.001 18.7 0.5 0.0013 18.3 0.4 1.2 1 0 0 1 1 1 1 IncA protein SEFIR PF08357.6 ETO17392.1 - 0.0036 17.3 0.3 0.0051 16.8 0.2 1.2 1 0 0 1 1 1 1 SEFIR domain ACBP PF00887.14 ETO17392.1 - 0.018 14.6 0.0 0.05 13.2 0.0 1.7 1 0 0 1 1 1 0 Acyl CoA binding protein X8 PF07983.8 ETO17392.1 - 0.025 15.0 0.1 0.052 14.0 0.1 1.6 1 0 0 1 1 1 0 X8 domain ATG27 PF09451.5 ETO17394.1 - 0.76 8.9 7.1 1.1 8.3 4.9 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 WD40 PF00400.27 ETO17395.1 - 1e-08 34.7 0.1 0.0094 15.8 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat eIF2A PF08662.6 ETO17395.1 - 0.015 15.0 0.0 0.065 12.9 0.0 1.9 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A GATase PF00117.23 ETO17395.1 - 0.17 11.3 3.0 0.093 12.1 0.2 1.9 2 0 0 2 2 2 0 Glutamine amidotransferase class-I UpxZ PF06603.6 ETO17396.1 - 0.12 12.3 0.0 0.32 11.0 0.0 1.6 2 0 0 2 2 2 0 UpxZ family of transcription anti-terminator antagonists PUB PF09409.5 ETO17397.1 - 0.017 14.8 2.7 0.084 12.6 1.9 2.0 1 1 0 1 1 1 0 PUB domain D123 PF07065.9 ETO17398.1 - 1.4e-19 70.3 4.3 7.5e-19 67.9 2.9 1.9 1 1 0 1 1 1 1 D123 DUF4343 PF14243.1 ETO17398.1 - 0.00082 19.2 3.7 0.002 17.9 2.5 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4343) Plasmodium_Vir PF05795.6 ETO17399.1 - 0.0031 16.7 20.1 0.1 11.7 5.7 2.5 1 1 1 2 2 2 2 Plasmodium vivax Vir protein Tetraspannin PF00335.15 ETO17399.1 - 0.011 15.0 4.7 0.095 11.9 3.3 2.2 1 1 0 1 1 1 0 Tetraspanin family DUF4131 PF13567.1 ETO17399.1 - 0.016 14.6 0.0 1.4 8.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) O-antigen_lig PF13425.1 ETO17399.1 - 0.056 13.4 1.2 12 5.8 0.9 2.3 2 0 0 2 2 2 0 O-antigen ligase like membrane protein DUF3753 PF12575.3 ETO17399.1 - 0.057 13.2 5.0 1.2 9.0 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) EpsG PF14897.1 ETO17399.1 - 0.067 12.1 6.9 0.88 8.4 0.7 2.1 2 0 0 2 2 2 0 EpsG family AA_permease_2 PF13520.1 ETO17399.1 - 0.068 11.6 3.8 2.5 6.5 0.1 2.1 2 0 0 2 2 2 0 Amino acid permease TrkH PF02386.11 ETO17399.1 - 0.079 11.5 1.6 0.87 8.0 0.1 2.1 2 0 0 2 2 2 0 Cation transport protein zf-LITAF-like PF10601.4 ETO17399.1 - 0.18 11.7 5.8 0.17 11.8 1.2 2.3 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain DUF3810 PF12725.2 ETO17399.1 - 0.18 10.6 2.7 1.6 7.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) O-ag_pol_Wzy PF14296.1 ETO17399.1 - 0.26 9.8 11.7 0.21 10.1 2.2 2.1 2 0 0 2 2 2 0 O-antigen polysaccharide polymerase Wzy 7TM_GPCR_Srsx PF10320.4 ETO17399.1 - 0.41 9.7 8.0 2.9 6.9 1.2 2.2 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.16 ETO17399.1 - 1.9 7.5 8.8 0.74 8.8 0.3 2.5 3 0 0 3 3 3 0 7 transmembrane receptor (rhodopsin family) Sigma_reg_N PF13800.1 ETO17399.1 - 2.9 7.9 8.3 10 6.2 1.6 3.0 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Kelch_6 PF13964.1 ETO17400.1 - 7.1e-08 32.3 3.6 0.012 15.7 0.1 4.5 3 1 1 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO17400.1 - 0.0011 18.7 0.1 0.02 14.6 0.0 2.8 1 1 1 2 2 2 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO17400.1 - 0.091 12.9 0.0 0.69 10.1 0.0 2.3 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO17400.1 - 0.15 11.6 0.6 22 4.6 0.0 3.1 2 0 0 2 2 2 0 Kelch motif Kelch_2 PF07646.10 ETO17400.1 - 0.18 11.6 3.2 10 6.0 0.1 3.8 4 0 0 4 4 4 0 Kelch motif NusB PF01029.13 ETO17400.1 - 0.85 9.5 5.2 0.34 10.8 1.4 1.9 2 0 0 2 2 2 0 NusB family Y_phosphatase2 PF03162.8 ETO17402.1 - 4.1e-52 175.8 1.2 5.9e-52 175.3 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family AKAP7_NLS PF10469.4 ETO17402.1 - 6.5e-12 45.5 10.8 7.2e-11 42.1 7.4 2.5 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Y_phosphatase3 PF13350.1 ETO17402.1 - 0.036 14.2 0.0 0.036 14.2 0.0 2.9 5 0 0 5 5 5 0 Tyrosine phosphatase family Usp PF00582.21 ETO17402.1 - 0.059 13.5 0.4 0.85 9.8 0.6 2.5 2 0 0 2 2 2 0 Universal stress protein family LigT_PEase PF02834.11 ETO17402.1 - 0.069 13.1 1.0 27 4.8 0.0 3.5 3 1 0 3 3 3 0 LigT like Phosphoesterase Sigma70_ner PF04546.8 ETO17402.1 - 0.083 12.5 19.3 0.33 10.5 4.9 2.8 3 0 0 3 3 3 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.5 ETO17402.1 - 5.9 7.1 13.1 17 5.7 9.1 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Peptidase_S10 PF00450.17 ETO17404.1 - 3.1e-49 168.2 7.1 3.5e-49 168.0 4.9 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Ank_2 PF12796.2 ETO17405.1 - 1.5e-12 47.6 0.6 5e-12 45.9 0.3 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO17405.1 - 3.7e-10 39.7 3.8 2e-05 24.6 0.3 3.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO17405.1 - 9.1e-10 38.7 1.7 2.4e-07 31.0 0.2 3.5 2 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 ETO17405.1 - 1.8e-08 33.7 0.4 0.00011 21.7 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 ETO17405.1 - 1.9e-05 24.4 1.2 0.014 15.5 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat SCP1201-deam PF14428.1 ETO17405.1 - 0.073 12.7 0.1 2.3 7.9 0.0 2.2 2 0 0 2 2 2 0 SCP1.201-like deaminase Peptidase_S10 PF00450.17 ETO17406.1 - 5.3e-32 111.5 0.2 5.8e-32 111.3 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Glyco_transf_64 PF09258.5 ETO17406.1 - 0.12 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 64 domain Peptidase_S10 PF00450.17 ETO17407.1 - 3.6e-09 36.2 0.0 4.3e-09 36.0 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase PH_4 PF15404.1 ETO17409.1 - 1.5 8.3 5.4 3.6 7.0 3.8 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain LTD PF00932.14 ETO17410.1 - 2.8e-05 24.1 0.1 2.8e-05 24.1 0.1 2.4 2 2 1 3 3 3 1 Lamin Tail Domain DARPP-32 PF05395.7 ETO17410.1 - 1.9 8.6 7.8 2.7 8.1 5.4 1.2 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Helicase_C PF00271.26 ETO17412.1 - 1.2e-27 95.5 0.3 2.1e-27 94.8 0.2 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain tRNA-synt_1b PF00579.20 ETO17412.1 - 0.032 13.3 0.0 0.037 13.1 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) DUF3010 PF11215.3 ETO17414.1 - 0.013 15.4 0.0 0.018 14.9 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3010) DUF912 PF06024.7 ETO17415.1 - 0.0085 16.1 4.3 0.0085 16.1 3.0 2.0 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1390 PF07150.6 ETO17415.1 - 2.9 7.1 9.5 0.85 8.9 4.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1390) WD40 PF00400.27 ETO17417.1 - 1.8e-33 113.2 17.4 4.6e-10 38.9 0.5 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat zf-TRAF PF02176.13 ETO17417.1 - 2e-05 24.8 2.5 2e-05 24.8 1.7 2.5 2 0 0 2 2 2 1 TRAF-type zinc finger Nup160 PF11715.3 ETO17417.1 - 2.6e-05 22.5 11.4 0.0018 16.4 0.2 3.6 3 1 0 4 4 4 3 Nucleoporin Nup120/160 DUF3987 PF13148.1 ETO17417.1 - 0.078 11.5 1.4 0.12 10.9 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Uso1_p115_C PF04871.8 ETO17417.1 - 4.9 7.0 11.4 12 5.8 7.9 1.6 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DivIC PF04977.10 ETO17417.1 - 5.6 6.5 11.1 14 5.2 0.3 3.0 3 0 0 3 3 3 0 Septum formation initiator PUA_2 PF14306.1 ETO17418.1 - 0.0028 17.0 0.4 0.0084 15.5 0.0 1.9 1 1 0 2 2 2 1 PUA-like domain MAAL_C PF07476.6 ETO17418.1 - 0.044 12.6 2.3 0.061 12.2 1.6 1.3 1 1 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus DUF2240 PF09999.4 ETO17418.1 - 0.053 12.9 0.5 0.11 11.9 0.3 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2240) UPF0184 PF03670.8 ETO17418.1 - 0.096 12.8 1.3 0.14 12.3 0.1 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) HisK_N PF09385.5 ETO17418.1 - 0.13 11.8 2.6 0.12 11.9 0.8 1.8 1 1 0 1 1 1 0 Histidine kinase N terminal IncA PF04156.9 ETO17418.1 - 0.17 11.4 15.9 0.23 11.0 11.0 1.1 1 0 0 1 1 1 0 IncA protein AATF-Che1 PF13339.1 ETO17418.1 - 0.87 9.7 14.4 1.4 9.0 9.9 1.4 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF310 PF03750.8 ETO17418.1 - 1 9.5 6.1 1.7 8.8 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF310) DUF3573 PF12097.3 ETO17418.1 - 4 5.9 9.8 4.8 5.6 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF4083 PF13314.1 ETO17418.1 - 8.3 6.3 7.6 1.5 8.7 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4083) Zeta_toxin PF06414.7 ETO17419.1 - 1.3e-08 34.1 0.0 2.3e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 ETO17419.1 - 0.037 13.8 0.0 0.083 12.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain Phytoreo_S7 PF07236.6 ETO17419.1 - 0.1 10.8 0.1 0.14 10.4 0.0 1.1 1 0 0 1 1 1 0 Phytoreovirus S7 protein Zeta_toxin PF06414.7 ETO17420.1 - 0.00061 18.9 0.1 0.00077 18.6 0.1 1.1 1 0 0 1 1 1 1 Zeta toxin DUF3244 PF11589.3 ETO17420.1 - 0.0029 17.2 0.2 0.0044 16.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3244) Aa_trans PF01490.13 ETO17421.1 - 3.9e-31 107.9 5.7 4.9e-31 107.6 3.5 1.6 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein AIP3 PF03915.8 ETO17421.1 - 0.068 12.0 2.0 0.1 11.5 1.4 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 Clathrin PF00637.15 ETO17422.1 - 1.8e-11 43.8 1.6 5.2e-07 29.3 0.4 2.5 2 0 0 2 2 2 2 Region in Clathrin and VPS DUF2410 PF10307.4 ETO17422.1 - 0.023 14.0 0.4 0.038 13.3 0.3 1.3 1 0 0 1 1 1 0 Hypothetical protein (DUF2410) 2OG-FeII_Oxy_3 PF13640.1 ETO17423.1 - 9.3e-05 22.8 0.3 0.00096 19.6 0.1 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF2304 PF10066.4 ETO17423.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) Pkinase PF00069.20 ETO17424.1 - 3.2e-21 75.6 0.0 3.8e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO17424.1 - 1.2e-06 27.8 0.7 1.1e-05 24.7 0.5 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Sec7 PF01369.15 ETO17425.1 - 4.6e-06 26.4 1.8 9.1e-06 25.4 1.3 1.5 1 1 0 1 1 1 1 Sec7 domain AIG2 PF06094.7 ETO17425.1 - 0.12 12.8 0.2 0.63 10.5 0.1 2.0 1 1 1 2 2 2 0 AIG2-like family Cas_csx3 PF09620.5 ETO17426.1 - 0.041 13.6 0.1 0.06 13.1 0.1 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) Sec62 PF03839.11 ETO17427.1 - 0.0029 17.0 0.1 0.0046 16.3 0.1 1.3 1 0 0 1 1 1 1 Translocation protein Sec62 FYVE PF01363.16 ETO17428.1 - 5.3e-13 48.6 15.5 1.3e-12 47.4 10.7 1.7 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 ETO17428.1 - 0.038 13.9 10.2 0.12 12.2 7.1 1.9 1 1 1 2 2 2 0 FYVE-type zinc finger zf-RING_2 PF13639.1 ETO17429.1 - 1.8e-06 27.7 3.8 4.5e-06 26.3 2.6 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 ETO17429.1 - 3.2e-06 26.6 2.9 8e-06 25.4 2.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO17429.1 - 0.00058 19.4 3.5 0.0016 18.0 2.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETO17429.1 - 0.0032 17.5 6.4 0.0059 16.6 4.5 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 ETO17429.1 - 0.0059 16.3 3.2 0.011 15.3 2.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 ETO17429.1 - 0.032 14.2 4.1 0.066 13.2 2.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 ETO17429.1 - 0.055 13.0 6.5 0.12 12.0 4.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn-ribbon_8 PF09723.5 ETO17429.1 - 0.22 11.4 2.4 0.72 9.8 0.4 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-HC5HC2H PF13771.1 ETO17429.1 - 0.27 11.4 3.2 0.44 10.7 2.1 1.6 1 1 0 1 1 1 0 PHD-like zinc-binding domain Myc_N PF01056.13 ETO17429.1 - 0.36 9.9 1.8 0.39 9.8 1.3 1.1 1 0 0 1 1 1 0 Myc amino-terminal region zf-Apc11 PF12861.2 ETO17429.1 - 0.41 10.5 3.9 0.78 9.6 2.7 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.2 ETO17429.1 - 0.47 10.3 4.6 4.6 7.1 3.2 2.3 1 1 0 1 1 1 0 Double zinc ribbon MAGP PF05507.6 ETO17429.1 - 0.55 10.0 4.1 0.69 9.7 2.9 1.3 1 1 0 1 1 1 0 Microfibril-associated glycoprotein (MAGP) IBR PF01485.16 ETO17429.1 - 1.9 8.4 6.6 4.1 7.3 4.6 1.8 1 1 0 1 1 1 0 IBR domain F_bP_aldolase PF01116.15 ETO17430.1 - 0.09 11.8 0.1 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II Peptidase_S30 PF01577.11 ETO17432.1 - 1.2 8.4 7.2 1.5 8.1 5.0 1.1 1 0 0 1 1 1 0 Potyvirus P1 protease DUF4407 PF14362.1 ETO17432.1 - 6.2 5.6 10.7 7.3 5.4 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DAP PF15228.1 ETO17432.1 - 6.6 7.5 11.7 0.75 10.5 3.4 2.1 1 1 1 2 2 2 0 Death-associated protein HEAT PF02985.17 ETO17433.1 - 0.0005 19.9 1.2 0.28 11.3 0.0 3.6 3 0 0 3 3 3 2 HEAT repeat Cnd1 PF12717.2 ETO17433.1 - 0.013 15.3 3.6 0.29 10.9 2.5 2.5 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.5 ETO17433.1 - 0.038 13.5 0.2 0.038 13.5 0.2 2.5 2 1 0 2 2 2 0 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 ETO17433.1 - 0.045 14.0 0.1 0.18 12.1 0.0 2.0 1 1 0 1 1 1 0 HEAT repeats HEAT_EZ PF13513.1 ETO17433.1 - 0.081 13.4 0.4 12 6.5 0.0 2.8 2 0 0 2 2 2 0 HEAT-like repeat CsrA PF02599.11 ETO17434.1 - 0.013 15.2 5.3 4.6 7.0 0.1 4.7 4 1 0 4 4 4 0 Global regulator protein family OMP_b-brl_2 PF13568.1 ETO17434.1 - 0.055 13.2 7.0 2 8.1 0.3 5.2 1 1 2 3 3 3 0 Outer membrane protein beta-barrel domain Filament PF00038.16 ETO17435.1 - 0.0047 16.4 13.3 0.17 11.3 1.5 2.1 2 0 0 2 2 2 2 Intermediate filament protein DASH_Spc34 PF08657.5 ETO17435.1 - 0.0072 16.0 5.1 0.1 12.2 0.0 2.1 2 0 0 2 2 2 1 DASH complex subunit Spc34 ATG16 PF08614.6 ETO17435.1 - 0.035 13.9 11.2 0.087 12.6 2.0 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF488 PF04343.8 ETO17435.1 - 0.046 14.0 0.9 0.046 14.0 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF488 ADIP PF11559.3 ETO17435.1 - 0.96 9.3 15.4 0.71 9.7 2.4 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Mst1_SARAH PF11629.3 ETO17435.1 - 1.2 8.9 4.5 5.2 6.9 0.3 3.1 3 0 0 3 3 3 0 C terminal SARAH domain of Mst1 DUF848 PF05852.6 ETO17435.1 - 1.3 8.9 9.0 1.1 9.1 1.6 2.1 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Atg14 PF10186.4 ETO17435.1 - 1.4 7.7 8.9 4.2 6.2 0.4 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Fib_alpha PF08702.5 ETO17435.1 - 1.6 8.8 11.4 0.33 11.0 1.9 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Bap31 PF05529.7 ETO17435.1 - 3.3 7.1 11.6 2.4 7.5 1.6 2.1 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Tropomyosin_1 PF12718.2 ETO17435.1 - 4.1 7.2 18.6 0.61 9.9 2.7 2.2 2 0 0 2 2 2 0 Tropomyosin like IncA PF04156.9 ETO17435.1 - 7.8 6.0 8.8 11 5.4 0.3 2.1 2 0 0 2 2 2 0 IncA protein Pkinase PF00069.20 ETO17436.1 - 1.5e-79 266.7 0.0 2.6e-79 266.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO17436.1 - 3.8e-40 137.6 0.0 5.7e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETO17436.1 - 4.3e-05 23.3 0.1 0.00061 19.5 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 ETO17436.1 - 0.0019 17.2 0.0 0.0041 16.1 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETO17436.1 - 0.0034 16.4 0.1 0.008 15.2 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 ETO17436.1 - 0.027 13.8 0.1 0.072 12.4 0.0 1.8 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL AAA_21 PF13304.1 ETO17438.1 - 1.1e-25 91.1 12.1 1.8e-23 83.9 8.4 2.4 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 ETO17438.1 - 1.3e-15 57.4 17.9 2e-13 50.2 12.4 2.6 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 ETO17438.1 - 2e-13 50.1 1.2 4e-12 45.8 0.8 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_tran PF00005.22 ETO17438.1 - 1e-07 32.3 1.8 0.00039 20.7 1.3 2.5 1 1 0 1 1 1 1 ABC transporter AAA_23 PF13476.1 ETO17438.1 - 5e-07 30.2 18.9 3.2e-06 27.6 13.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_13 PF13166.1 ETO17438.1 - 2.6e-05 22.9 9.7 0.00017 20.2 0.4 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 ETO17438.1 - 0.00023 20.6 0.0 0.00046 19.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.7 ETO17438.1 - 0.0077 15.8 0.0 0.046 13.3 0.0 2.1 2 0 0 2 2 2 1 NACHT domain ATP_bind_1 PF03029.12 ETO17438.1 - 0.022 14.2 0.2 0.6 9.6 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF258 PF03193.11 ETO17438.1 - 0.025 13.7 0.0 0.052 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PhoH PF02562.11 ETO17438.1 - 0.035 13.3 0.1 0.32 10.1 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.1 ETO17438.1 - 0.05 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 ETO17438.1 - 0.057 14.2 0.1 0.3 11.8 0.0 2.2 1 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 ETO17438.1 - 0.096 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Sulfotransfer_3 PF13469.1 ETO17439.1 - 8.7 7.2 14.1 5.2 7.9 7.2 2.4 2 1 0 2 2 2 0 Sulfotransferase family Glyco_hydro_47 PF01532.15 ETO17440.1 - 1.1e-07 30.8 3.3 1.6e-07 30.3 0.0 1.8 1 1 1 2 2 2 1 Glycosyl hydrolase family 47 Dicty_REP PF05086.7 ETO17440.1 - 0.018 12.8 6.1 0.022 12.5 4.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tir_receptor_C PF07489.6 ETO17440.1 - 0.12 12.0 5.8 0.15 11.8 4.0 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Mucin PF01456.12 ETO17440.1 - 0.23 11.2 15.2 0.3 10.8 10.5 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.6 ETO17440.1 - 0.39 8.6 12.5 0.5 8.2 8.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MSA_2 PF00985.12 ETO17440.1 - 3.6 7.6 12.0 4.9 7.2 8.3 1.1 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family Glyco_hydro_47 PF01532.15 ETO17441.1 - 2.6e-34 118.6 1.1 2.6e-34 118.6 0.8 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 47 YjgP_YjgQ PF03739.9 ETO17442.1 - 2.6e-05 23.1 0.7 2.6e-05 23.1 0.5 1.7 2 0 0 2 2 2 1 Predicted permease YjgP/YjgQ family DUF2721 PF11026.3 ETO17442.1 - 0.0087 15.6 2.8 0.0087 15.6 2.0 2.8 4 0 0 4 4 4 1 Protein of unknown function (DUF2721) NOA36 PF06524.7 ETO17442.1 - 0.017 14.3 1.4 0.017 14.3 0.9 2.7 3 0 0 3 3 3 0 NOA36 protein SPX PF03105.14 ETO17442.1 - 1.1 8.9 25.5 0.08 12.7 1.0 3.1 2 1 0 3 3 3 0 SPX domain Pyr_redox_dim PF02852.17 ETO17443.1 - 5.1e-30 103.7 0.2 8.4e-30 103.0 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 ETO17443.1 - 1.5e-06 28.1 0.0 4.4e-06 26.7 0.0 1.8 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase PTS_2-RNA PF01885.11 ETO17444.1 - 1.4e-37 128.7 0.8 7.2e-36 123.2 0.5 2.2 1 1 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family NUDIX PF00293.23 ETO17444.1 - 1.3e-06 28.0 0.0 3e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain GATase PF00117.23 ETO17446.1 - 6.5e-50 169.2 0.1 2.9e-49 167.1 0.1 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I CTP_synth_N PF06418.9 ETO17446.1 - 2.7e-40 138.2 0.0 4.3e-40 137.5 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus Peptidase_C26 PF07722.8 ETO17446.1 - 7.3e-09 35.3 0.0 2e-07 30.6 0.0 2.3 1 1 0 1 1 1 1 Peptidase C26 PEGA PF08308.6 ETO17447.1 - 0.13 12.0 0.0 2.2 8.1 0.0 2.2 2 0 0 2 2 2 0 PEGA domain Podoplanin PF05808.6 ETO17450.1 - 0.042 13.4 3.5 0.059 12.9 2.4 1.1 1 0 0 1 1 1 0 Podoplanin Ank_2 PF12796.2 ETO17451.1 - 1.1e-12 48.1 0.3 1.7e-12 47.5 0.0 1.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO17451.1 - 8.3e-10 37.9 0.0 2.5e-06 27.0 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 ETO17451.1 - 4e-09 36.4 0.7 0.00015 21.9 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO17451.1 - 5.5e-08 32.3 0.0 0.00016 21.5 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 ETO17451.1 - 1.7e-06 28.3 0.0 2.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) APG6 PF04111.7 ETO17451.1 - 0.042 12.8 2.1 0.041 12.9 1.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 WHEP-TRS PF00458.15 ETO17451.1 - 0.11 12.1 0.4 0.11 12.1 0.2 2.8 3 0 0 3 3 3 0 WHEP-TRS domain DUF2423 PF10338.4 ETO17453.1 - 0.082 12.8 1.7 0.31 11.0 1.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2423) Mgr1 PF08602.5 ETO17453.1 - 7.2 5.5 10.3 0.32 9.9 2.8 1.8 2 0 0 2 2 2 0 Mgr1-like, i-AAA protease complex subunit Di19_C PF14571.1 ETO17454.1 - 0.032 14.5 0.9 0.032 14.5 0.6 3.0 2 1 1 3 3 3 0 Stress-induced protein Di19, C-terminal DUF4613 PF15390.1 ETO17454.1 - 7.9 4.5 18.5 9.8 4.2 12.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Kinesin PF00225.18 ETO17456.1 - 2.8e-07 29.5 0.0 6e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain FTR PF01913.13 ETO17459.1 - 0.0056 16.4 5.5 0.0056 16.4 3.8 1.5 2 0 0 2 2 2 1 Formylmethanofuran-tetrahydromethanopterin formyltransferase DUF2201_N PF13203.1 ETO17459.1 - 0.33 10.0 2.5 0.48 9.5 1.7 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Reprolysin_4 PF13583.1 ETO17460.1 - 0.042 13.3 0.1 0.066 12.7 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF349 PF03993.7 ETO17460.1 - 0.12 12.5 5.5 0.59 10.3 0.7 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Actin PF00022.14 ETO17461.1 - 8.4e-12 44.2 0.0 1.2e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Actin zf-RING_2 PF13639.1 ETO17462.1 - 1.5e-07 31.1 2.5 2.2e-07 30.6 1.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 ETO17462.1 - 0.00018 21.5 1.7 0.00038 20.5 1.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger RINGv PF12906.2 ETO17462.1 - 0.00063 19.7 3.5 0.0011 18.9 2.4 1.4 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4 PF00097.20 ETO17462.1 - 0.00074 19.1 3.6 0.0013 18.3 2.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO17462.1 - 0.011 15.4 2.9 0.017 14.8 2.0 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 ETO17462.1 - 0.012 15.6 4.7 0.02 14.8 3.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 ETO17462.1 - 0.021 14.5 3.5 0.043 13.5 2.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.3 ETO17462.1 - 0.047 13.6 2.1 0.11 12.5 1.4 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.1 ETO17462.1 - 0.082 12.5 2.8 0.12 12.0 2.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Baculo_RING PF05883.6 ETO17462.1 - 0.083 12.7 3.2 0.22 11.3 2.2 1.8 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-Apc11 PF12861.2 ETO17462.1 - 0.097 12.5 0.3 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Phage_Gp23 PF10669.4 ETO17462.1 - 8.6 6.4 7.2 21 5.2 5.0 1.7 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Fez1 PF06818.10 ETO17464.1 - 0.11 12.4 23.6 0.28 11.1 16.4 1.6 1 1 0 1 1 1 0 Fez1 BTK PF00779.14 ETO17464.1 - 0.38 10.3 2.6 0.73 9.5 1.8 1.5 1 0 0 1 1 1 0 BTK motif DUF3450 PF11932.3 ETO17464.1 - 0.49 9.6 14.5 0.96 8.6 4.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) DUF1664 PF07889.7 ETO17464.1 - 2.2 8.0 7.8 0.19 11.5 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Sulfotransfer_1 PF00685.22 ETO17465.1 - 1.5e-05 24.3 0.1 4.7e-05 22.7 0.1 1.7 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 ETO17465.1 - 0.019 15.9 7.4 0.071 14.0 5.1 1.9 1 1 0 1 1 1 0 Sulfotransferase family Pkinase PF00069.20 ETO17466.1 - 3e-63 213.3 0.6 4.5e-63 212.8 0.4 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO17466.1 - 7.6e-36 123.5 2.7 7.6e-34 116.9 1.9 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 ETO17466.1 - 3.3e-05 23.3 2.2 6.8e-05 22.2 1.6 1.6 1 1 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 ETO17466.1 - 0.00038 19.5 0.2 0.00086 18.3 0.1 1.7 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.15 ETO17466.1 - 0.0009 18.8 0.3 0.0016 18.0 0.2 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 ETO17466.1 - 0.0011 18.7 0.1 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 ETO17466.1 - 0.061 12.3 0.1 0.096 11.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lin-8 PF03353.10 ETO17467.1 - 0.56 9.4 20.7 0.84 8.8 14.4 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist OsmC PF02566.14 ETO17468.1 - 2.9e-06 27.3 0.0 3.8e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 OsmC-like protein ATC_hydrolase PF14196.1 ETO17468.1 - 0.026 14.9 0.0 0.031 14.6 0.0 1.1 1 0 0 1 1 1 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase IncA PF04156.9 ETO17469.1 - 0.0056 16.2 21.2 0.0096 15.5 14.7 1.4 1 0 0 1 1 1 1 IncA protein AAA_27 PF13514.1 ETO17469.1 - 0.0098 13.6 14.2 0.012 13.4 9.9 1.2 1 0 0 1 1 1 1 AAA domain DUF2353 PF09789.4 ETO17469.1 - 0.011 15.0 18.5 0.031 13.5 10.6 1.9 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) DUF342 PF03961.8 ETO17469.1 - 0.024 13.0 17.3 0.027 12.8 12.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Toxin_48 PF15528.1 ETO17469.1 - 0.026 14.4 1.6 0.032 14.1 0.9 1.3 1 1 0 1 1 1 0 Putative toxin 48 GAS PF13851.1 ETO17469.1 - 0.037 13.2 27.0 0.11 11.7 18.7 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding SAA PF00277.13 ETO17469.1 - 0.071 13.4 1.0 0.2 12.0 0.3 1.9 2 0 0 2 2 2 0 Serum amyloid A protein DUF1886 PF09171.5 ETO17469.1 - 0.077 12.0 3.9 0.076 12.0 1.8 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1886) APG6 PF04111.7 ETO17469.1 - 0.091 11.7 22.4 0.1 11.5 15.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Dabb PF07876.7 ETO17469.1 - 0.14 12.5 2.9 0.34 11.3 1.9 1.9 1 1 0 1 1 1 0 Stress responsive A/B Barrel Domain BLOC1_2 PF10046.4 ETO17469.1 - 0.23 11.6 22.7 0.17 12.0 3.8 3.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mnd1 PF03962.10 ETO17469.1 - 0.29 10.7 19.1 0.4 10.3 13.2 1.4 1 0 0 1 1 1 0 Mnd1 family TruB_N PF01509.13 ETO17469.1 - 0.34 11.0 3.8 0.42 10.7 2.6 1.2 1 0 0 1 1 1 0 TruB family pseudouridylate synthase (N terminal domain) CHASE3 PF05227.8 ETO17469.1 - 0.55 9.8 15.2 0.67 9.6 8.0 2.1 1 1 1 2 2 2 0 CHASE3 domain Prefoldin_3 PF13758.1 ETO17469.1 - 0.58 9.9 10.8 0.16 11.7 3.3 2.2 1 1 0 2 2 2 0 Prefoldin subunit Reo_sigmaC PF04582.7 ETO17469.1 - 0.6 9.2 2.8 0.71 9.0 1.9 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Mod_r PF07200.8 ETO17469.1 - 0.81 9.5 23.1 0.6 10.0 14.7 1.6 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Cupin_8 PF13621.1 ETO17469.1 - 0.83 9.0 9.1 0.99 8.8 6.3 1.1 1 0 0 1 1 1 0 Cupin-like domain DUF2205 PF10224.4 ETO17469.1 - 0.9 9.1 16.6 0.22 11.0 1.8 2.4 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) UPF0029 PF01205.14 ETO17469.1 - 1 9.0 4.0 1.4 8.6 2.6 1.4 1 1 0 1 1 1 0 Uncharacterized protein family UPF0029 MbeD_MobD PF04899.7 ETO17469.1 - 1.1 9.1 11.5 2.9 7.8 6.1 2.4 1 1 1 2 2 2 0 MbeD/MobD like CENP-F_leu_zip PF10473.4 ETO17469.1 - 1.3 8.9 25.8 5.8 6.7 3.3 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CCDC155 PF14662.1 ETO17469.1 - 1.7 8.1 25.5 3 7.3 0.6 1.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Phage_GP20 PF06810.6 ETO17469.1 - 2.2 7.7 24.1 5.5 6.4 16.2 1.9 1 1 0 1 1 1 0 Phage minor structural protein GP20 Jnk-SapK_ap_N PF09744.4 ETO17469.1 - 2.5 8.1 21.7 3.3 7.6 1.3 2.5 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 Occludin_ELL PF07303.8 ETO17469.1 - 2.5 8.8 13.7 1.5 9.5 7.8 1.8 1 1 1 2 2 2 0 Occludin homology domain ERM PF00769.14 ETO17469.1 - 2.5 7.5 28.3 3.8 6.9 19.5 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Fib_alpha PF08702.5 ETO17469.1 - 2.9 7.9 17.4 7.2 6.7 12.1 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF2229 PF09989.4 ETO17469.1 - 3.4 7.0 9.4 3.6 6.9 6.2 1.3 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) ACR_tran PF00873.14 ETO17469.1 - 3.5 4.9 12.6 3.8 4.7 8.8 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Seryl_tRNA_N PF02403.17 ETO17469.1 - 3.6 7.6 19.6 1.3 9.1 10.6 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HSP70 PF00012.15 ETO17469.1 - 3.6 5.3 18.2 4.2 5.1 12.6 1.0 1 0 0 1 1 1 0 Hsp70 protein DUF2203 PF09969.4 ETO17469.1 - 3.8 7.7 10.6 2.8 8.1 6.0 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) V_ATPase_I PF01496.14 ETO17469.1 - 3.8 5.2 15.0 4.4 5.0 10.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.6 ETO17469.1 - 4.2 5.9 22.2 0.52 8.9 7.8 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein COG2 PF06148.6 ETO17469.1 - 5.7 6.8 13.4 0.36 10.7 1.4 2.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_MLP1_2 PF07926.7 ETO17469.1 - 7.3 6.3 28.4 19 5.0 19.7 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.1 ETO17469.1 - 9.4 4.5 19.6 11 4.3 13.6 1.1 1 0 0 1 1 1 0 AAA domain CAP_GLY PF01302.20 ETO17470.1 - 7.1e-08 32.0 0.1 4.1e-07 29.5 0.1 2.1 1 1 0 1 1 1 1 CAP-Gly domain TraT PF05818.7 ETO17473.1 - 0.15 11.4 3.3 0.29 10.5 2.3 1.4 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Tropomyosin_1 PF12718.2 ETO17473.1 - 5 6.9 15.7 0.21 11.4 0.8 2.3 2 0 0 2 2 2 0 Tropomyosin like RmuC PF02646.11 ETO17474.1 - 4.4e-50 170.2 17.4 1.9e-47 161.5 0.4 3.5 1 1 2 3 3 3 2 RmuC family DUF2232 PF09991.4 ETO17474.1 - 0.46 9.4 4.0 0.44 9.5 0.7 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) DUF3139 PF11337.3 ETO17474.1 - 1 9.7 11.0 0.035 14.3 1.5 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3139) Carb_kinase PF01256.12 ETO17475.1 - 2.2e-48 164.6 0.0 2.5e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.10 ETO17475.1 - 1.8e-08 33.8 0.0 5.4e-08 32.3 0.0 1.6 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.7 ETO17475.1 - 1.1e-05 24.7 0.1 6.3e-05 22.2 0.0 2.0 1 1 0 2 2 2 1 Phosphomethylpyrimidine kinase SAM_2 PF07647.12 ETO17477.1 - 0.00083 19.1 0.3 0.0022 17.8 0.1 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO17477.1 - 0.0011 19.1 0.3 0.0025 17.9 0.1 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Lipoprotein_7 PF01540.11 ETO17477.1 - 0.044 12.8 0.3 0.05 12.6 0.2 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein DUF4515 PF14988.1 ETO17477.1 - 0.052 13.2 2.7 0.098 12.3 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) Cullin_binding PF03556.10 ETO17477.1 - 0.22 11.6 3.0 0.31 11.2 2.1 1.3 1 1 0 1 1 1 0 Cullin binding PDZ PF00595.19 ETO17478.1 - 0.00081 19.5 0.1 0.0016 18.5 0.1 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) RAI16-like PF10257.4 ETO17481.1 - 0.026 13.4 0.8 0.028 13.3 0.6 1.1 1 0 0 1 1 1 0 Retinoic acid induced 16-like protein UPF0233 PF06781.7 ETO17481.1 - 8.6 6.0 7.5 2.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) AAA PF00004.24 ETO17482.1 - 0.01 16.0 0.7 0.58 10.3 0.2 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 ETO17483.1 - 5.4e-34 117.2 0.2 1.3e-33 115.9 0.1 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 ETO17483.1 - 0.003 17.5 0.0 0.0053 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) NfeD PF01957.13 ETO17484.1 - 1.7 8.7 8.5 52 3.9 2.5 3.5 2 2 0 3 3 3 0 NfeD-like C-terminal, partner-binding DEAD_2 PF06733.10 ETO17485.1 - 0.0024 17.3 0.1 0.0039 16.5 0.1 1.3 1 0 0 1 1 1 1 DEAD_2 Folate_carrier PF01770.13 ETO17485.1 - 0.0035 15.8 3.0 0.0044 15.5 2.0 1.1 1 0 0 1 1 1 1 Reduced folate carrier DUF1212 PF06738.7 ETO17486.1 - 6.6 6.1 7.0 1.4 8.3 0.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1212) Tubulin PF00091.20 ETO17487.1 - 2.1e-61 207.5 0.1 4.2e-61 206.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO17487.1 - 5.9e-27 94.1 0.1 1.1e-26 93.3 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Gly_kinase PF02595.10 ETO17487.1 - 0.012 14.3 0.0 0.018 13.7 0.0 1.1 1 0 0 1 1 1 0 Glycerate kinase family Glutaredoxin2_C PF04399.8 ETO17487.1 - 0.049 13.2 0.1 0.85 9.2 0.0 2.4 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain Misat_Tub_SegII PF10644.4 ETO17487.1 - 0.072 13.1 0.1 0.21 11.6 0.0 1.9 2 0 0 2 2 2 0 Misato Segment II tubulin-like domain WD40 PF00400.27 ETO17488.1 - 9.2e-79 256.7 21.6 3.3e-12 45.7 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO17488.1 - 9.7e-13 48.2 2.9 0.00014 21.6 0.2 3.8 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO17488.1 - 3.8e-09 35.2 15.5 0.039 12.0 0.1 6.4 1 1 6 7 7 7 5 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO17488.1 - 7.6e-05 21.1 1.5 0.51 8.5 0.0 3.4 1 1 3 4 4 4 2 Cytochrome D1 heme domain DUF1513 PF07433.6 ETO17488.1 - 0.00011 21.2 0.3 0.9 8.3 0.0 4.0 1 1 3 5 5 5 2 Protein of unknown function (DUF1513) Nucleoporin_N PF08801.6 ETO17488.1 - 0.00074 18.3 10.9 0.085 11.5 3.9 4.6 1 1 2 3 3 3 1 Nup133 N terminal like PD40 PF07676.7 ETO17488.1 - 0.0013 18.3 2.7 2.7 7.7 0.0 5.3 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 ETO17488.1 - 0.0089 15.1 1.5 1.2 8.1 0.0 3.4 2 1 1 4 4 4 1 Protein of unknown function (DUF1258) Hira PF07569.6 ETO17488.1 - 0.009 15.2 1.5 11 5.2 0.0 4.1 2 2 3 5 5 5 1 TUP1-like enhancer of split Resistin PF06954.6 ETO17488.1 - 0.33 11.2 4.0 17 5.7 0.0 4.2 4 2 3 7 7 7 0 Resistin Tom37_C PF11801.3 ETO17490.1 - 0.24 11.2 1.6 0.37 10.6 1.1 1.4 1 0 0 1 1 1 0 Tom37 C-terminal domain RRN3 PF05327.6 ETO17490.1 - 2.4 6.1 4.5 3 5.8 3.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2956 PF11169.3 ETO17490.1 - 5 7.1 8.5 7.9 6.5 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Hexapep PF00132.19 ETO17491.1 - 2e-15 55.5 11.6 1.6e-06 27.3 2.0 3.6 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 ETO17491.1 - 5.5e-11 41.8 11.7 5.9e-10 38.5 0.3 3.5 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Sushi_2 PF09014.5 ETO17491.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain G-alpha PF00503.15 ETO17492.1 - 2e-07 30.0 1.8 4e-07 29.0 1.3 1.6 1 1 0 1 1 1 1 G-protein alpha subunit NB-ARC PF00931.17 ETO17492.1 - 0.006 15.4 0.2 0.0097 14.7 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_17 PF13207.1 ETO17492.1 - 0.0099 16.6 0.0 0.012 16.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 ETO17492.1 - 0.01 16.1 0.1 0.015 15.5 0.1 1.3 1 0 0 1 1 1 0 ABC transporter Rad17 PF03215.10 ETO17492.1 - 0.013 14.1 0.0 0.014 14.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 ETO17492.1 - 0.053 13.2 0.2 0.09 12.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 ETO17492.1 - 0.054 13.0 0.4 0.084 12.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain MCM PF00493.18 ETO17492.1 - 0.06 12.1 0.0 0.072 11.8 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family AAA_29 PF13555.1 ETO17492.1 - 0.09 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 ETO17492.1 - 0.095 12.1 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Arf PF00025.16 ETO17492.1 - 0.1 11.8 1.0 0.14 11.4 0.1 1.6 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_28 PF13521.1 ETO17492.1 - 0.11 12.4 0.4 0.21 11.5 0.1 1.5 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 ETO17492.1 - 0.12 11.3 1.0 0.36 9.8 0.3 1.9 1 1 1 2 2 2 0 Septin UPF0079 PF02367.12 ETO17492.1 - 0.15 11.7 0.3 0.32 10.6 0.2 1.6 1 1 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 WD40 PF00400.27 ETO17493.1 - 0.00013 21.6 3.7 0.00089 19.0 0.1 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO17493.1 - 0.012 13.7 0.1 0.016 13.4 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 G-alpha PF00503.15 ETO17497.1 - 4.6e-23 81.5 0.8 6e-23 81.1 0.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit ABC_tran PF00005.22 ETO17497.1 - 0.00032 21.0 0.5 0.00041 20.6 0.3 1.3 1 1 0 1 1 1 1 ABC transporter Arf PF00025.16 ETO17497.1 - 0.0011 18.2 0.1 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 ETO17497.1 - 0.0037 17.7 0.1 0.0061 17.0 0.1 1.5 1 1 0 1 1 1 1 Miro-like protein AAA_29 PF13555.1 ETO17497.1 - 0.013 14.9 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 ETO17497.1 - 0.02 14.8 0.2 0.036 14.0 0.1 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase TrwB_AAD_bind PF10412.4 ETO17497.1 - 0.032 12.8 1.3 0.25 9.9 0.1 2.2 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain SRPRB PF09439.5 ETO17497.1 - 0.034 13.3 0.1 0.071 12.3 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.1 ETO17497.1 - 0.035 14.0 0.2 0.063 13.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 ETO17497.1 - 0.073 13.3 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 ETO17497.1 - 0.073 11.9 1.0 0.15 10.8 0.7 1.7 1 1 0 1 1 1 0 NB-ARC domain FtsK_SpoIIIE PF01580.13 ETO17497.1 - 0.1 12.0 0.1 0.33 10.3 0.0 1.8 2 1 1 3 3 3 0 FtsK/SpoIIIE family AAA_33 PF13671.1 ETO17497.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 ETO17497.1 - 0.14 13.0 0.2 0.24 12.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain MotB_plug PF13677.1 ETO17498.1 - 0.084 12.1 1.5 0.41 9.9 1.0 2.2 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB Noc2 PF03715.8 ETO17499.1 - 1.4e-18 66.7 4.3 2.8e-18 65.8 2.9 1.4 1 1 0 1 1 1 1 Noc2p family Noc2 PF03715.8 ETO17500.1 - 2.5e-24 85.6 5.7 9.5e-24 83.7 4.0 1.8 1 1 0 1 1 1 1 Noc2p family Vfa1 PF08432.5 ETO17500.1 - 0.0062 16.5 1.5 0.0062 16.5 1.0 2.7 2 1 0 2 2 2 1 AAA-ATPase Vps4-associated protein 1 Zip PF02535.17 ETO17500.1 - 0.021 13.8 4.6 0.31 10.0 0.0 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter DUF913 PF06025.7 ETO17500.1 - 2.7 6.6 15.2 4.2 6.0 0.3 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Pox_Ag35 PF03286.9 ETO17500.1 - 5.6 6.4 32.9 0.33 10.4 4.9 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Nucleoplasmin PF03066.10 ETO17501.1 - 0.073 12.5 6.0 0.15 11.5 4.2 1.6 1 1 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 ETO17501.1 - 1 8.5 8.0 1.4 8.1 5.5 1.2 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.1 ETO17501.1 - 1.6 9.0 10.4 3.3 8.0 7.2 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 ETO17501.1 - 2.6 8.3 9.9 5.2 7.3 6.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.7 ETO17501.1 - 3.3 7.3 19.5 0.15 11.7 7.0 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.8 ETO17501.1 - 4.3 6.8 7.8 9.5 5.7 5.4 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.7 ETO17501.1 - 5 4.9 13.4 7.5 4.3 9.3 1.2 1 0 0 1 1 1 0 Nop14-like family WD40 PF00400.27 ETO17503.1 - 3e-07 30.0 1.3 0.0016 18.2 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat Sporozoite_P67 PF05642.6 ETO17503.1 - 0.037 11.9 9.5 0.044 11.6 1.0 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Menin PF05053.8 ETO17503.1 - 0.081 11.0 4.4 0.099 10.7 3.1 1.1 1 0 0 1 1 1 0 Menin Porin_3 PF01459.17 ETO17504.1 - 9.5e-05 21.8 0.0 0.0002 20.7 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic porin IL17 PF06083.6 ETO17504.1 - 0.18 11.8 2.7 2.1 8.4 0.5 2.6 2 0 0 2 2 2 0 Interleukin-17 Pox_Ag35 PF03286.9 ETO17505.1 - 0.0061 16.1 12.2 0.011 15.2 6.9 2.0 2 0 0 2 2 2 1 Pox virus Ag35 surface protein FAM176 PF14851.1 ETO17505.1 - 0.05 13.2 8.6 0.11 12.1 5.9 1.6 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.9 ETO17505.1 - 0.098 10.6 10.4 0.12 10.3 7.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 ETO17505.1 - 0.11 11.0 18.4 0.11 10.9 12.8 1.1 1 0 0 1 1 1 0 Daxx Family RXT2_N PF08595.6 ETO17505.1 - 0.16 11.7 7.9 0.33 10.7 5.5 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal RRN3 PF05327.6 ETO17505.1 - 0.25 9.3 8.6 0.32 9.0 6.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TRAP_alpha PF03896.11 ETO17505.1 - 0.37 9.7 5.7 0.7 8.8 3.9 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Vfa1 PF08432.5 ETO17505.1 - 0.45 10.5 10.7 0.84 9.6 7.4 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TraH_2 PF06871.6 ETO17505.1 - 0.53 9.6 3.0 0.91 8.9 2.1 1.3 1 0 0 1 1 1 0 TraH_2 NARP1 PF12569.3 ETO17505.1 - 0.65 8.6 6.2 0.89 8.2 4.3 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 BTV_NS2 PF04514.7 ETO17505.1 - 1.8 7.3 10.3 2.2 7.0 7.1 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Sporozoite_P67 PF05642.6 ETO17505.1 - 2.6 5.7 6.8 3.7 5.2 4.7 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen VID27 PF08553.5 ETO17505.1 - 3.7 5.6 11.9 5.1 5.2 8.2 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF605 PF04652.11 ETO17505.1 - 4.6 6.5 13.0 6.8 5.9 9.0 1.2 1 0 0 1 1 1 0 Vta1 like FLO_LFY PF01698.11 ETO17505.1 - 8.3 5.1 10.1 14 4.3 7.0 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF3306 PF11748.3 ETO17505.1 - 9.7 6.8 10.8 26 5.4 7.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Cytokin_check_N PF10407.4 ETO17506.1 - 0.0055 16.2 1.0 0.011 15.3 0.7 1.5 1 1 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus Multi_ubiq PF14452.1 ETO17506.1 - 0.13 12.2 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Multiubiquitin CopC PF04234.7 ETO17506.1 - 0.14 12.8 0.2 0.19 12.3 0.1 1.4 1 0 0 1 1 1 0 CopC domain SH3_1 PF00018.23 ETO17507.1 - 2.7e-25 87.5 6.0 4.3e-13 48.4 0.5 2.6 2 1 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 ETO17507.1 - 4.1e-21 74.3 4.0 8.1e-10 38.1 0.4 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 ETO17507.1 - 5.7e-20 70.5 0.2 1e-09 37.7 0.0 2.2 2 0 0 2 2 2 2 Variant SH3 domain VHP PF02209.14 ETO17507.1 - 1.1e-13 50.6 0.2 1.1e-13 50.6 0.1 1.7 2 0 0 2 2 2 1 Villin headpiece domain DUF3104 PF11302.3 ETO17507.1 - 0.0019 17.5 0.9 0.33 10.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3104) Mucin PF01456.12 ETO17507.1 - 0.074 12.8 13.0 0.11 12.3 9.0 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein FH2 PF02181.18 ETO17508.1 - 2.2e-08 33.3 4.5 2.2e-08 33.3 3.1 1.6 2 0 0 2 2 2 1 Formin Homology 2 Domain TYA PF01021.14 ETO17508.1 - 5.1 7.3 6.1 2.2 8.5 0.2 2.1 2 0 0 2 2 2 0 TYA transposon protein Pox_E2-like PF04497.7 ETO17509.1 - 0.00095 17.3 1.9 0.0011 17.0 1.4 1.1 1 0 0 1 1 1 1 Poxviridae protein DUF1632 PF07857.7 ETO17509.1 - 0.02 14.1 1.0 0.02 14.1 0.7 1.6 1 1 1 2 2 2 0 CEO family (DUF1632) DUF2090 PF09863.4 ETO17509.1 - 0.033 13.0 0.2 0.083 11.7 0.0 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2090) Ndc1_Nup PF09531.5 ETO17509.1 - 0.24 9.7 7.9 0.25 9.7 5.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Neur_chan_memb PF02932.11 ETO17509.1 - 1.4 8.7 7.9 1.9 8.3 5.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.7 ETO17509.1 - 1.8 8.3 8.1 2.5 7.9 5.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.12 ETO17509.1 - 9.7 4.9 6.0 11 4.6 4.2 1.1 1 0 0 1 1 1 0 Presenilin zf-TRAF PF02176.13 ETO17510.1 - 4.7e-06 26.8 7.6 6.5e-06 26.4 3.7 2.5 2 0 0 2 2 2 1 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 ETO17510.1 - 1.1 9.3 14.1 0.27 11.3 1.1 3.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF2413 PF10310.4 ETO17511.1 - 0.81 8.4 16.9 0.93 8.2 11.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) HAND PF09110.6 ETO17511.1 - 3.1 8.2 14.5 6.8 7.1 10.1 1.6 1 1 0 1 1 1 0 HAND WD40 PF00400.27 ETO17512.1 - 1.8e-05 24.4 0.3 0.00054 19.7 0.1 2.7 3 0 0 3 3 3 1 WD domain, G-beta repeat Ninjurin PF04923.7 ETO17512.1 - 0.054 13.2 2.7 0.2 11.3 1.8 1.9 1 1 0 1 1 1 0 Ninjurin DUF4389 PF14333.1 ETO17512.1 - 1.6 8.4 10.1 2.9 7.6 1.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4389) Neur_chan_memb PF02932.11 ETO17513.1 - 0.0035 17.2 0.2 0.005 16.7 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region TRAP_alpha PF03896.11 ETO17513.1 - 0.0044 16.0 4.8 0.0089 15.0 0.2 2.1 2 0 0 2 2 2 1 Translocon-associated protein (TRAP), alpha subunit Peptidase_S49_N PF08496.5 ETO17513.1 - 0.0095 15.7 2.7 0.0095 15.7 1.9 2.3 2 0 0 2 2 2 1 Peptidase family S49 N-terminal Pox_Ag35 PF03286.9 ETO17513.1 - 0.023 14.2 12.1 0.04 13.4 0.4 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein FAM176 PF14851.1 ETO17513.1 - 0.023 14.3 7.7 0.12 12.0 0.3 2.3 2 0 0 2 2 2 0 FAM176 family Glucos_trans_II PF14264.1 ETO17513.1 - 0.045 12.7 0.0 0.057 12.4 0.0 1.1 1 0 0 1 1 1 0 Glucosyl transferase GtrII DUF4401 PF14351.1 ETO17513.1 - 0.045 12.7 0.1 0.057 12.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) Bap31 PF05529.7 ETO17513.1 - 0.085 12.3 10.6 0.025 14.0 1.5 2.3 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like RNA_pol_3_Rpc31 PF11705.3 ETO17513.1 - 0.095 12.6 13.2 0.38 10.6 0.4 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 SID-1_RNA_chan PF13965.1 ETO17513.1 - 0.32 9.1 4.4 0.041 12.0 0.1 1.6 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 DUF1754 PF08555.5 ETO17513.1 - 1.3 9.6 23.0 1.2 9.7 4.6 2.5 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) CLPTM1 PF05602.7 ETO17513.1 - 2 7.0 6.9 0.12 11.0 0.9 1.7 2 0 0 2 2 2 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF4628 PF15429.1 ETO17513.1 - 2.9 7.2 9.1 0.13 11.6 1.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4628) DUF3276 PF11680.3 ETO17513.1 - 3.6 7.3 15.1 3.9 7.2 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3276) DUF3899 PF13038.1 ETO17513.1 - 6.5 6.9 19.8 2.1 8.5 2.6 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3899) Ribosomal_L6e PF01159.14 ETO17513.1 - 9.9 6.4 14.4 1.1 9.5 1.4 2.6 2 0 0 2 2 2 0 Ribosomal protein L6e PP2C PF00481.16 ETO17514.1 - 3.5e-17 62.6 2.6 6.6e-12 45.3 0.0 2.1 1 1 1 2 2 2 2 Protein phosphatase 2C Actino_peptide PF14408.1 ETO17514.1 - 0.055 13.4 2.6 0.095 12.6 1.8 1.4 1 0 0 1 1 1 0 Ribosomally synthesized peptide in actinomycetes Acyl-CoA_ox_N PF14749.1 ETO17515.1 - 0.52 10.6 4.0 0.16 12.2 0.5 1.8 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal DUF445 PF04286.7 ETO17518.1 - 0.1 12.1 0.4 0.1 12.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Glutaredoxin PF00462.19 ETO17519.1 - 2.6e-06 27.2 0.1 6e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 Glutaredoxin Pkinase PF00069.20 ETO17520.1 - 7.6e-24 84.2 0.0 1e-23 83.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO17520.1 - 4.2e-06 26.0 0.0 1.2e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Glyco_transf_49 PF13896.1 ETO17521.1 - 2.1e-10 40.2 0.0 2.1e-10 40.2 0.0 1.4 2 0 0 2 2 2 1 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 ETO17521.1 - 4.8e-05 22.5 0.0 7.7e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 ETO17521.1 - 0.0014 18.3 0.0 0.0038 16.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 RsmJ PF04378.8 ETO17522.1 - 0.029 13.3 0.2 0.062 12.2 0.1 1.5 1 0 0 1 1 1 0 Ribosomal RNA small subunit methyltransferase D, RsmJ Fib_alpha PF08702.5 ETO17523.1 - 0.0083 16.2 2.4 0.0083 16.2 1.6 2.6 1 1 1 2 2 2 1 Fibrinogen alpha/beta chain family WBP-1 PF11669.3 ETO17523.1 - 0.014 15.4 3.2 0.043 13.8 0.2 2.6 2 0 0 2 2 2 0 WW domain-binding protein 1 DUF1216 PF06746.6 ETO17523.1 - 0.046 13.4 6.3 0.36 10.5 1.7 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1216) Bap31 PF05529.7 ETO17523.1 - 0.081 12.3 0.0 0.081 12.3 0.0 3.0 3 1 0 3 3 3 0 B-cell receptor-associated protein 31-like YMF19 PF02326.10 ETO17523.1 - 0.12 12.9 4.1 0.37 11.4 0.1 3.3 3 2 0 3 3 3 0 Plant ATP synthase F0 Reo_sigmaC PF04582.7 ETO17523.1 - 0.13 11.4 2.8 0.22 10.6 0.1 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF2972 PF11186.3 ETO17523.1 - 0.23 11.3 7.9 0.029 14.2 2.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2972) APH PF01636.18 ETO17523.1 - 0.62 9.7 5.2 1.8 8.1 0.2 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family CENP-F_leu_zip PF10473.4 ETO17523.1 - 5 6.9 20.2 0.046 13.5 2.4 3.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UspB PF10625.4 ETO17524.1 - 0.05 13.3 0.1 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Universal stress protein B (UspB) DUF342 PF03961.8 ETO17525.1 - 0.23 9.8 2.9 0.48 8.7 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF342) RyR PF02026.11 ETO17526.1 - 5e-13 48.8 0.0 2e-09 37.3 0.0 2.4 2 0 0 2 2 2 2 RyR domain WD40 PF00400.27 ETO17527.1 - 2.1e-06 27.3 0.1 3.8e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 WD domain, G-beta repeat YmzC PF14157.1 ETO17527.1 - 0.08 12.7 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 YmzC-like protein WES_acyltransf PF03007.11 ETO17528.1 - 1e-05 25.2 0.0 0.11 12.0 0.0 2.1 2 0 0 2 2 2 2 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF3543 PF12063.3 ETO17529.1 - 0.00014 21.1 1.8 0.009 15.2 0.7 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3543) Sigma70_ner PF04546.8 ETO17529.1 - 0.00058 19.5 13.4 0.00077 19.1 6.6 2.3 2 0 0 2 2 2 1 Sigma-70, non-essential region Nop14 PF04147.7 ETO17529.1 - 0.01 13.8 17.0 0.013 13.4 11.8 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 ETO17529.1 - 0.02 12.9 14.2 0.03 12.3 9.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 ETO17529.1 - 0.15 10.4 14.3 0.21 10.0 9.9 1.2 1 0 0 1 1 1 0 Daxx Family CENP-T PF15511.1 ETO17529.1 - 0.18 10.9 12.8 0.088 12.0 7.5 1.4 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Astro_capsid PF03115.9 ETO17529.1 - 0.2 9.9 6.2 0.23 9.6 4.3 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor RRN3 PF05327.6 ETO17529.1 - 0.29 9.1 8.5 0.38 8.7 5.9 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TRAP_alpha PF03896.11 ETO17529.1 - 0.31 10.0 7.4 0.51 9.2 5.1 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2457 PF10446.4 ETO17529.1 - 0.44 9.2 28.0 0.87 8.2 19.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Skp1 PF01466.14 ETO17530.1 - 5.5e-39 132.0 0.7 1.3e-38 130.8 0.5 1.7 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 ETO17530.1 - 4.5e-05 23.4 0.1 0.00017 21.5 0.0 2.0 2 1 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 ETO17530.1 - 0.0046 16.9 0.8 0.041 13.8 0.6 2.1 1 1 0 1 1 1 1 BTB/POZ domain Vasculin PF15337.1 ETO17530.1 - 0.17 12.3 1.2 0.36 11.3 0.8 1.5 1 0 0 1 1 1 0 Vascular protein family Vasculin-like 1 FAD-oxidase_C PF02913.14 ETO17531.1 - 2.1e-53 181.1 0.0 2.5e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 ETO17531.1 - 2.1e-11 43.4 0.2 3.7e-11 42.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain DUF3861 PF12977.2 ETO17531.1 - 0.075 13.1 0.0 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3861) DUF1616 PF07760.6 ETO17532.1 - 0.00019 20.6 0.1 0.00055 19.1 0.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1616) DUF3347 PF11827.3 ETO17532.1 - 0.17 11.8 9.5 0.24 11.3 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) SAM_2 PF07647.12 ETO17533.1 - 4.2e-16 58.5 0.6 4.2e-09 36.1 0.0 2.1 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO17533.1 - 1.5e-09 37.9 0.5 0.00026 21.0 0.0 2.2 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) HAP1_N PF04849.8 ETO17533.1 - 0.045 12.6 0.0 0.057 12.3 0.0 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DIL PF01843.14 ETO17533.1 - 0.087 12.7 0.2 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 DIL domain TPR_11 PF13414.1 ETO17534.1 - 2.4e-20 71.9 16.6 5.5e-07 29.1 0.0 6.1 3 2 4 7 7 7 6 TPR repeat TPR_1 PF00515.23 ETO17534.1 - 1.8e-16 58.9 16.5 0.00088 18.7 0.3 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO17534.1 - 4.7e-16 57.3 18.8 0.0094 15.7 0.6 9.1 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.1 ETO17534.1 - 3.2e-14 52.6 7.8 5.5e-06 26.2 0.1 5.1 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO17534.1 - 6.4e-14 50.6 8.9 0.16 11.8 0.0 8.0 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO17534.1 - 2.9e-12 45.7 2.6 0.15 12.3 0.0 6.9 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO17534.1 - 5.3e-12 45.8 0.1 0.0002 21.6 0.0 4.8 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO17534.1 - 3.9e-09 36.3 1.3 0.012 16.1 0.0 5.3 5 2 1 6 6 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO17534.1 - 1.3e-08 35.2 0.0 0.012 16.2 0.0 4.4 5 0 0 5 5 3 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO17534.1 - 2.1e-08 34.1 6.8 0.0016 18.5 0.0 4.9 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETO17534.1 - 8.6e-06 25.8 2.5 7.7 7.2 0.0 5.9 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETO17534.1 - 1.1e-05 25.1 0.0 0.11 12.3 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO17534.1 - 1.6e-05 24.3 1.6 1.4 8.9 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETO17534.1 - 0.0016 18.2 0.7 2.1 8.3 0.0 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO17534.1 - 0.015 15.1 3.3 0.51 10.2 0.0 4.1 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.1 ETO17534.1 - 0.04 12.9 0.2 0.25 10.3 0.0 2.4 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF605 PF04652.11 ETO17534.1 - 0.65 9.3 41.6 0.023 14.0 2.8 2.2 2 0 0 2 2 2 0 Vta1 like TPR_3 PF07720.7 ETO17534.1 - 7.6 6.4 8.9 2.4 8.0 0.1 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat Kelch_6 PF13964.1 ETO17535.1 - 0.0021 18.1 0.4 0.036 14.2 0.0 2.7 2 1 1 3 3 3 1 Kelch motif Kelch_5 PF13854.1 ETO17535.1 - 0.66 9.9 3.1 1.7 8.6 0.0 2.5 2 1 0 2 2 2 0 Kelch motif B56 PF01603.15 ETO17536.1 - 3.7e-93 312.3 7.6 4.1e-93 312.2 5.3 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF3369 PF11849.3 ETO17537.1 - 0.16 11.9 0.7 0.24 11.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3369) Lipase_3 PF01764.20 ETO17538.1 - 3.6e-09 36.3 0.0 6.2e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Wax2_C PF12076.3 ETO17538.1 - 0.12 12.1 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 WAX2 C-terminal domain NOGCT PF08155.6 ETO17539.1 - 2.6e-19 68.6 1.4 5.9e-19 67.5 1.0 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.18 ETO17539.1 - 2.8e-14 53.0 0.0 6.9e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETO17539.1 - 2.5e-12 46.3 0.1 1e-10 41.0 0.1 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B NOG1 PF06858.9 ETO17539.1 - 1.4e-07 31.3 1.8 0.0043 16.8 0.0 2.7 1 1 1 2 2 2 2 Nucleolar GTP-binding protein 1 (NOG1) GTP_EFTU PF00009.22 ETO17539.1 - 0.00071 19.0 0.2 0.0064 15.9 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.16 ETO17539.1 - 0.018 14.2 0.0 1.6 7.9 0.0 2.6 3 0 0 3 3 3 0 ADP-ribosylation factor family AAA_18 PF13238.1 ETO17539.1 - 0.018 15.3 0.6 0.14 12.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF258 PF03193.11 ETO17539.1 - 0.056 12.6 0.0 0.19 10.8 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Asp PF00026.18 ETO17540.1 - 4.6e-19 68.8 0.1 5.6e-19 68.5 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 ETO17540.1 - 4.9e-11 42.4 0.0 1.1e-09 38.0 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Sec23_helical PF04815.10 ETO17540.1 - 0.02 14.3 0.1 6.7 6.2 0.0 2.2 2 0 0 2 2 2 0 Sec23/Sec24 helical domain Ras PF00071.17 ETO17542.1 - 3.2e-10 39.6 2.3 9.2e-05 21.8 0.5 2.9 1 1 1 2 2 2 2 Ras family Miro PF08477.8 ETO17542.1 - 0.0014 19.1 0.1 0.0076 16.7 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein DUF4211 PF13926.1 ETO17542.1 - 0.014 14.7 0.0 0.46 9.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4211) TAXi_C PF14541.1 ETO17543.1 - 0.032 13.7 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Na_Ala_symp PF01235.12 ETO17543.1 - 0.18 10.3 0.0 0.22 10.0 0.0 1.1 1 0 0 1 1 1 0 Sodium:alanine symporter family Hydrolase_3 PF08282.7 ETO17543.1 - 0.23 10.9 3.2 0.13 11.7 0.6 1.8 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF1053 PF06327.9 ETO17543.1 - 7.9 6.8 6.5 15 5.9 0.2 3.2 3 1 0 3 3 3 0 Domain of Unknown Function (DUF1053) Glyco_transf_49 PF13896.1 ETO17544.1 - 0.0015 17.6 0.0 0.0033 16.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glyco_transf_49 PF13896.1 ETO17545.1 - 1.1e-28 100.2 2.8 2.2e-28 99.2 1.9 1.5 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 ETO17545.1 - 1.6e-05 24.1 0.3 6.5e-05 22.1 0.1 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 CDC45 PF02724.9 ETO17546.1 - 0.0023 16.0 16.3 0.0023 16.0 11.3 2.8 2 1 1 3 3 3 1 CDC45-like protein Menin PF05053.8 ETO17546.1 - 3.3 5.7 8.8 0.73 7.9 3.1 1.9 2 0 0 2 2 2 0 Menin TFIIF_alpha PF05793.7 ETO17547.1 - 0.63 8.3 32.9 0.85 7.9 22.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PEX-1N PF09262.6 ETO17548.1 - 7.2e-12 45.1 1.2 3.7e-11 42.9 0.0 2.4 2 1 1 3 3 3 1 Peroxisome biogenesis factor 1, N-terminal Thiolase_N PF00108.18 ETO17548.1 - 0.01 14.8 0.1 0.014 14.4 0.0 1.2 1 0 0 1 1 1 0 Thiolase, N-terminal domain YoaP PF14268.1 ETO17548.1 - 0.021 14.0 0.1 0.042 13.0 0.0 1.4 1 0 0 1 1 1 0 YoaP-like FimP PF09766.4 ETO17550.1 - 0.39 9.7 16.0 0.019 14.0 1.2 2.3 2 0 0 2 2 2 0 Fms-interacting protein DRY_EERY PF09750.4 ETO17552.1 - 6.4 6.9 12.8 0.94 9.5 5.7 1.9 2 0 0 2 2 2 0 Alternative splicing regulator FAM150 PF15129.1 ETO17555.1 - 0.18 11.7 6.3 0.061 13.1 0.9 2.4 2 1 0 2 2 2 0 FAM150 family BCL9 PF11502.3 ETO17555.1 - 0.21 11.1 0.2 0.21 11.1 0.1 2.1 2 0 0 2 2 2 0 B-cell lymphoma 9 protein RNase_H2_suC PF08615.6 ETO17555.1 - 0.74 9.6 7.2 0.4 10.5 0.3 2.4 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF2201_N PF13203.1 ETO17555.1 - 1.7 7.7 18.0 0.087 11.9 1.4 2.1 2 0 0 2 2 2 0 Putative metallopeptidase domain Ribosomal_S25 PF03297.10 ETO17555.1 - 5.6 7.0 10.9 1.9 8.5 2.5 2.5 2 0 0 2 2 2 0 S25 ribosomal protein PDCD2_C PF04194.8 ETO17555.1 - 7.4 6.1 13.2 1.8 8.1 4.0 2.2 2 0 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain DUF605 PF04652.11 ETO17557.1 - 0.33 10.2 11.8 0.13 11.6 6.5 1.4 2 0 0 2 2 2 0 Vta1 like EF-hand_1 PF00036.27 ETO17558.1 - 2e-08 32.9 3.3 1e-05 24.4 0.3 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 ETO17558.1 - 9.3e-08 31.3 2.2 0.00058 19.5 0.1 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 ETO17558.1 - 2.3e-07 29.8 3.6 2.9e-06 26.3 0.3 2.8 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 ETO17558.1 - 1e-06 28.7 5.5 0.00023 21.2 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 ETO17558.1 - 1.6e-05 24.4 3.2 0.018 14.6 0.1 2.9 3 0 0 3 3 2 2 EF-hand domain pair LMBR1 PF04791.11 ETO17558.1 - 0.023 13.2 6.5 0.036 12.6 4.5 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Hid1 PF12722.2 ETO17558.1 - 0.039 11.6 24.0 0.052 11.2 16.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SDA1 PF05285.7 ETO17558.1 - 0.11 11.7 49.7 0.19 10.9 34.4 1.4 1 0 0 1 1 1 0 SDA1 Peptidase_S64 PF08192.6 ETO17558.1 - 0.13 10.6 14.6 0.17 10.2 10.1 1.2 1 0 0 1 1 1 0 Peptidase family S64 CENP-T PF15511.1 ETO17558.1 - 0.24 10.5 27.3 0.38 9.9 18.9 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T SprA-related PF12118.3 ETO17558.1 - 0.27 10.5 29.3 0.42 9.9 20.3 1.4 1 0 0 1 1 1 0 SprA-related family Herpes_LMP1 PF05297.6 ETO17558.1 - 1.8 7.4 11.9 2.6 6.8 8.3 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) SNF2_N PF00176.18 ETO17559.1 - 1.5e-75 253.7 1.1 1.9e-75 253.4 0.8 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 ETO17559.1 - 1.2e-08 34.6 0.0 2.7e-08 33.4 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 ETO17559.1 - 8.1e-08 31.4 0.2 1.8e-07 30.2 0.0 1.7 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.1 ETO17559.1 - 2e-06 28.0 0.0 1.7e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 ETO17559.1 - 1.1e-05 25.2 0.2 0.0001 22.1 0.0 2.5 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_14 PF13173.1 ETO17559.1 - 0.03 14.2 0.1 0.15 11.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain DEAD_2 PF06733.10 ETO17559.1 - 0.04 13.3 0.0 0.09 12.1 0.0 1.6 1 0 0 1 1 1 0 DEAD_2 MobB PF03205.9 ETO17559.1 - 0.089 12.4 0.0 0.42 10.3 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TPR_11 PF13414.1 ETO17560.1 - 1.5e-10 40.5 3.6 3e-06 26.7 0.2 2.3 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETO17560.1 - 2.2e-07 30.1 2.7 0.0011 18.5 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO17560.1 - 1e-06 28.1 3.5 0.026 14.4 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO17560.1 - 0.0015 18.3 0.3 5.4 6.9 0.0 3.3 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.1 ETO17560.1 - 0.0016 18.7 2.5 0.53 10.6 0.5 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO17560.1 - 0.0054 16.4 0.4 0.032 14.0 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO17560.1 - 0.01 16.3 0.4 0.95 10.2 0.1 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETO17560.1 - 0.041 14.5 2.3 1.3 9.8 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETO17560.1 - 0.063 13.2 3.7 1.5 8.8 0.2 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat HPIH PF13323.1 ETO17560.1 - 0.16 11.6 2.5 0.58 9.8 0.2 2.4 1 1 1 2 2 2 0 N-terminal domain with HPIH motif Neur_chan_memb PF02932.11 ETO17560.1 - 1.4 8.7 4.2 2.5 7.9 2.9 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region YMF19 PF02326.10 ETO17560.1 - 2.8 8.5 7.3 0.18 12.4 0.2 2.7 3 2 0 3 3 3 0 Plant ATP synthase F0 Rap_GAP PF02145.10 ETO17561.1 - 5.8e-54 182.3 0.0 7.8e-54 181.9 0.0 1.1 1 0 0 1 1 1 1 Rap/ran-GAP ApoB100_C PF12491.3 ETO17561.1 - 0.041 13.5 0.0 0.079 12.6 0.0 1.4 1 0 0 1 1 1 0 Apolipoprotein B100 C terminal CENP-T PF15511.1 ETO17563.1 - 0.0056 15.9 28.4 0.0071 15.6 19.7 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T BUD22 PF09073.5 ETO17563.1 - 0.87 8.5 45.4 1.2 8.1 31.4 1.2 1 0 0 1 1 1 0 BUD22 Hid1 PF12722.2 ETO17563.1 - 2.9 5.4 22.5 3.2 5.3 15.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PLRV_ORF5 PF01690.12 ETO17563.1 - 3.2 6.8 28.3 3.9 6.5 19.6 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein TPR_12 PF13424.1 ETO17564.1 - 7.9e-91 298.0 15.5 1.9e-19 69.3 0.2 5.9 3 2 3 7 7 7 6 Tetratricopeptide repeat TPR_10 PF13374.1 ETO17564.1 - 2.5e-56 186.1 0.0 2.2e-09 36.9 0.0 9.3 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_11 PF13414.1 ETO17564.1 - 7.3e-43 144.0 18.5 4.5e-10 39.0 0.0 7.1 4 2 2 7 7 7 7 TPR repeat TPR_1 PF00515.23 ETO17564.1 - 3.3e-42 140.3 31.3 4.8e-06 25.9 0.2 10.0 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.12 ETO17564.1 - 2.9e-35 117.3 23.4 0.00027 20.6 0.0 10.0 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_7 PF13176.1 ETO17564.1 - 1.3e-32 108.9 5.3 0.00046 19.7 0.0 10.0 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_8 PF13181.1 ETO17564.1 - 1.3e-24 84.0 23.8 0.00098 18.7 0.3 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_17 PF13431.1 ETO17564.1 - 2.2e-12 46.1 8.1 1.6 9.1 0.1 8.2 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO17564.1 - 4.4e-11 42.4 0.0 0.38 11.5 0.0 8.0 5 2 4 9 9 9 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO17564.1 - 2.3e-08 34.4 0.0 0.32 11.7 0.0 6.1 4 1 2 6 6 5 1 Tetratricopeptide repeat MIT PF04212.13 ETO17564.1 - 2.7e-07 30.3 18.0 0.7 9.8 0.0 8.3 8 1 1 9 9 9 3 MIT (microtubule interacting and transport) domain PPR PF01535.15 ETO17564.1 - 0.00018 21.2 8.6 4.4 7.4 0.0 6.5 8 0 0 8 8 7 1 PPR repeat DUF386 PF04074.7 ETO17564.1 - 0.00022 20.7 3.1 0.11 12.0 0.1 3.1 2 1 1 3 3 3 2 Domain of unknown function (DUF386) TPR_6 PF13174.1 ETO17564.1 - 0.00029 21.0 4.0 33 5.2 0.0 6.7 9 0 0 9 9 6 0 Tetratricopeptide repeat RPN7 PF10602.4 ETO17564.1 - 0.0011 18.4 11.0 1.6 8.1 0.2 5.2 4 2 1 5 5 5 2 26S proteasome subunit RPN7 GST_C_3 PF14497.1 ETO17564.1 - 0.0034 17.8 0.1 0.02 15.3 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain TPR_19 PF14559.1 ETO17564.1 - 0.012 15.9 0.3 0.48 10.8 0.0 3.6 3 1 1 4 4 3 0 Tetratricopeptide repeat DUF357 PF04010.8 ETO17564.1 - 0.017 14.7 3.8 2.3 7.9 0.0 4.9 5 1 0 5 5 5 0 Protein of unknown function (DUF357) PPR_1 PF12854.2 ETO17564.1 - 0.06 12.8 0.4 8.6 5.9 0.0 3.5 4 0 0 4 4 4 0 PPR repeat Cwf_Cwc_15 PF04889.7 ETO17564.1 - 0.46 10.1 13.3 0.78 9.4 9.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Exostosin PF03016.10 ETO17566.1 - 2.4e-06 26.8 0.0 3.8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Exostosin family AcylCoA_dehyd_C PF12186.3 ETO17566.1 - 0.075 12.8 0.9 0.15 11.9 0.1 1.8 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase C terminal DUF573 PF04504.9 ETO17566.1 - 0.36 11.1 0.1 0.36 11.1 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function, DUF573 BCIP PF13862.1 ETO17567.1 - 0.033 13.6 0.4 0.044 13.3 0.2 1.2 1 0 0 1 1 1 0 p21-C-terminal region-binding protein RicinB_lectin_2 PF14200.1 ETO17568.1 - 1.4e-29 102.5 1.0 5.1e-08 33.2 0.0 5.7 6 0 0 6 6 6 5 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 ETO17568.1 - 0.00053 20.0 5.3 2.3 8.2 0.5 4.5 4 1 1 5 5 5 3 Ricin-type beta-trefoil lectin domain Imm5 PF14423.1 ETO17570.1 - 0.17 11.4 16.4 0.053 13.1 1.2 3.0 4 0 0 4 4 4 0 Immunity protein Imm5 Phasin PF05597.6 ETO17570.1 - 0.25 11.1 5.4 1 9.0 0.5 2.9 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) BLOC1_2 PF10046.4 ETO17570.1 - 4.1 7.6 9.9 1.6 8.8 0.2 3.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cytochrom_B562 PF07361.6 ETO17573.1 - 1.7 9.0 6.9 14 6.1 0.0 2.9 2 1 1 3 3 3 0 Cytochrome b562 Pkinase PF00069.20 ETO17574.1 - 4.9e-27 94.7 0.0 6.8e-17 61.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO17574.1 - 1.7e-18 66.6 0.1 6.6e-18 64.7 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Lentiviral_Tat PF02998.9 ETO17574.1 - 0.068 13.0 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Lentiviral Tat protein CENP-B_dimeris PF09026.5 ETO17574.1 - 3.8 7.8 9.3 17 5.7 0.1 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CEP44 PF15007.1 ETO17575.1 - 5e-35 120.0 0.8 1.6e-34 118.4 0.6 1.9 1 1 0 1 1 1 1 Centrosomal spindle body, CEP44 WD40 PF00400.27 ETO17577.1 - 5.6e-25 86.2 11.2 1.6e-12 46.7 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO17577.1 - 1.1e-09 37.0 0.1 3.8e-05 22.0 0.1 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 WD40 PF00400.27 ETO17578.1 - 5.8e-83 270.0 23.7 4.3e-13 48.5 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO17578.1 - 3.6e-10 39.8 1.7 4.1e-05 23.3 0.1 2.8 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO17578.1 - 1.6e-09 36.4 12.2 0.0094 14.1 0.1 4.6 1 1 4 5 5 5 4 Nucleoporin Nup120/160 DUF1258 PF06869.7 ETO17578.1 - 1.4e-05 24.3 0.4 0.26 10.3 0.1 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF1258) PQQ_2 PF13360.1 ETO17578.1 - 3.1e-05 23.5 0.5 0.0023 17.4 0.1 2.9 1 1 1 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO17578.1 - 6.8e-05 21.3 2.4 0.098 10.9 0.1 2.9 1 1 1 3 3 3 3 Cytochrome D1 heme domain Resistin PF06954.6 ETO17578.1 - 0.00055 20.1 1.6 3.4 7.9 0.1 4.0 3 1 1 4 4 4 1 Resistin PD40 PF07676.7 ETO17578.1 - 0.013 15.1 4.7 2 8.1 0.0 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat SGL PF08450.7 ETO17578.1 - 0.014 14.8 0.7 0.029 13.7 0.1 1.9 2 1 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region DUF3732 PF12532.3 ETO17578.1 - 0.04 13.4 0.4 0.88 9.0 0.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3732) Hira PF07569.6 ETO17578.1 - 0.091 11.9 0.7 3.4 6.8 0.1 3.1 3 1 1 4 4 4 0 TUP1-like enhancer of split FAM219A PF15260.1 ETO17578.1 - 0.095 13.0 2.7 0.13 12.6 0.7 2.1 1 1 1 2 2 2 0 Protein family FAM219A DUF3601 PF12208.3 ETO17578.1 - 0.13 12.2 0.0 8.7 6.3 0.0 3.2 2 1 2 4 4 4 0 Domain of unknown function (DUF3601) Ricin_B_lectin PF00652.17 ETO17578.1 - 0.14 12.1 2.6 0.1 12.6 0.2 2.0 2 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain APP_N PF02177.11 ETO17578.1 - 0.17 11.8 2.7 3 7.8 0.5 3.1 1 1 3 4 4 4 0 Amyloid A4 N-terminal heparin-binding Proteasome_A_N PF10584.4 ETO17578.1 - 0.26 10.6 5.6 12 5.3 0.0 4.1 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature AAA_12 PF13087.1 ETO17579.1 - 1.3e-24 86.7 0.0 4.1e-24 85.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 ETO17579.1 - 2.5e-09 37.0 6.7 6.6e-06 25.8 0.0 2.9 3 0 0 3 3 3 2 AAA domain ETRAMP PF09716.5 ETO17579.1 - 0.32 10.9 8.9 0.34 10.8 1.2 2.4 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) BRF1 PF07741.8 ETO17580.1 - 0.048 13.8 4.1 0.074 13.2 2.8 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF3439 PF11921.3 ETO17580.1 - 0.062 13.0 9.8 0.091 12.5 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 ETO17580.1 - 0.098 12.4 21.9 0.13 12.0 15.2 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF819 PF05684.7 ETO17580.1 - 0.1 11.3 1.0 0.13 11.0 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF819) DUF3628 PF12300.3 ETO17580.1 - 0.24 11.4 4.8 0.33 10.9 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) TAF4 PF05236.9 ETO17580.1 - 0.25 10.5 7.0 0.37 10.0 4.9 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Med3 PF11593.3 ETO17580.1 - 0.85 8.7 11.0 1.2 8.2 7.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Dicty_REP PF05086.7 ETO17580.1 - 1.2 6.8 5.7 1.4 6.5 4.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pap_E4 PF02711.9 ETO17580.1 - 6.9 7.5 10.5 12 6.8 7.3 1.4 1 0 0 1 1 1 0 E4 protein Kei1 PF08552.6 ETO17580.1 - 8.4 6.0 6.6 11 5.6 4.6 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DNA_pol_A PF00476.15 ETO17581.1 - 2.2e-26 92.3 1.2 4.2e-14 51.9 0.2 2.2 2 0 0 2 2 2 2 DNA polymerase family A CDC45 PF02724.9 ETO17581.1 - 0.027 12.5 4.9 0.04 11.9 3.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 ETO17581.1 - 0.43 8.4 7.8 0.58 8.0 5.4 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 ETO17581.1 - 0.88 8.7 11.4 1.3 8.2 7.9 1.2 1 0 0 1 1 1 0 NOA36 protein Acyltransferase PF01553.16 ETO17582.1 - 4.1e-10 39.1 0.0 6.3e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase CDK2AP PF09806.4 ETO17583.1 - 3.2 7.9 18.2 0.89 9.7 3.3 2.4 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein MFS_1 PF07690.11 ETO17584.1 - 0.00013 20.8 8.8 0.0002 20.2 6.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETO17584.1 - 0.0018 16.9 6.5 0.0093 14.5 0.1 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter BLVR PF06375.6 ETO17584.1 - 0.5 10.1 4.9 0.62 9.8 3.4 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Tnp_P_element PF12017.3 ETO17585.1 - 0.028 13.6 0.0 0.074 12.2 0.0 1.6 1 1 1 2 2 2 0 Transposase protein DUF1604 PF07713.8 ETO17586.1 - 9 6.1 9.7 12 5.7 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1604) PBP1_TM PF14812.1 ETO17587.1 - 0.022 15.0 1.1 0.032 14.5 0.8 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BSP_II PF05432.6 ETO17587.1 - 0.047 12.9 8.7 0.06 12.6 6.0 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF2457 PF10446.4 ETO17587.1 - 1 8.0 7.8 1.2 7.8 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 ETO17587.1 - 7.1 5.7 8.7 8.6 5.5 6.0 1.1 1 0 0 1 1 1 0 NOA36 protein OspE PF02471.12 ETO17588.1 - 0.066 13.1 0.4 0.066 13.1 0.3 1.8 2 0 0 2 2 2 0 Borrelia outer surface protein E CIAPIN1 PF05093.8 ETO17588.1 - 2 8.5 5.0 0.71 9.9 0.6 2.1 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Prenyltrans PF00432.16 ETO17589.1 - 1.3e-16 59.7 2.9 2.1e-06 27.1 0.0 4.1 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 ETO17589.1 - 8e-14 52.0 0.1 3.9e-13 49.7 0.0 1.8 1 1 1 2 2 2 1 Prenyltransferase-like Prenyltrans_1 PF13243.1 ETO17589.1 - 0.021 14.8 0.1 0.084 12.8 0.0 1.9 1 1 1 2 2 2 0 Prenyltransferase-like EFG_II PF14492.1 ETO17589.1 - 0.06 13.2 0.0 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 Elongation Factor G, domain II Prenyltrans PF00432.16 ETO17590.1 - 8.6e-12 44.4 1.3 3.8e-05 23.1 0.2 2.2 2 0 0 2 2 2 2 Prenyltransferase and squalene oxidase repeat Myosin_HC-like PF07058.6 ETO17590.1 - 0.031 13.3 0.5 0.049 12.7 0.4 1.2 1 0 0 1 1 1 0 Myosin II heavy chain-like WTF PF03303.8 ETO17590.1 - 0.22 10.8 1.4 0.29 10.4 0.9 1.1 1 0 0 1 1 1 0 WTF protein zf-RING_2 PF13639.1 ETO17591.1 - 3.5e-06 26.7 0.7 3.5e-06 26.7 0.5 2.8 3 0 0 3 3 3 2 Ring finger domain zf-rbx1 PF12678.2 ETO17591.1 - 3.9e-06 26.8 0.2 3.9e-06 26.8 0.1 2.7 2 1 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 ETO17591.1 - 0.001 18.8 0.6 0.001 18.8 0.4 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 ETO17591.1 - 0.0033 17.4 0.7 0.0033 17.4 0.5 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO17591.1 - 0.0059 16.3 0.3 0.0059 16.3 0.2 2.9 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 ETO17591.1 - 0.013 15.1 0.5 0.013 15.1 0.3 3.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF3413 PF11893.3 ETO17593.1 - 0.081 11.7 2.2 0.17 10.7 1.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) DUF2439 PF10382.4 ETO17594.1 - 0.045 13.9 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2439) TLD PF07534.11 ETO17595.1 - 4.3e-16 59.1 0.2 6.5e-16 58.5 0.1 1.3 1 0 0 1 1 1 1 TLD YmaF PF12788.2 ETO17595.1 - 0.043 13.9 0.1 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 YmaF family Mito_carr PF00153.22 ETO17596.1 - 2.5e-15 55.9 4.4 5.7e-06 25.9 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Oxygenase-NA PF09859.4 ETO17598.1 - 0.12 11.7 0.5 0.24 10.7 0.3 1.4 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA LMBR1 PF04791.11 ETO17598.1 - 0.18 10.3 1.8 0.27 9.7 1.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Sulfatase PF00884.18 ETO17599.1 - 7.7e-13 48.2 0.0 9.6e-13 47.9 0.0 1.0 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 ETO17599.1 - 0.0011 18.3 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase FlxA PF14282.1 ETO17600.1 - 0.00043 20.1 16.5 0.00043 20.1 11.4 2.9 2 1 1 3 3 3 1 FlxA-like protein HALZ PF02183.13 ETO17600.1 - 0.00074 19.1 0.2 0.00074 19.1 0.1 3.9 3 1 1 4 4 4 1 Homeobox associated leucine zipper HOOK PF05622.7 ETO17600.1 - 0.0022 15.9 21.4 0.0022 15.9 14.9 1.6 2 0 0 2 2 2 1 HOOK protein DUF2240 PF09999.4 ETO17600.1 - 0.023 14.1 0.5 0.047 13.1 0.4 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2240) KLRAQ PF10205.4 ETO17600.1 - 0.025 14.6 7.0 0.025 14.6 4.8 3.2 2 1 1 3 3 3 0 Predicted coiled-coil domain-containing protein V_ATPase_I PF01496.14 ETO17600.1 - 0.08 10.7 11.5 0.14 9.9 7.9 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.7 ETO17600.1 - 0.16 11.7 8.2 0.18 11.6 0.5 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DivIVA PF05103.8 ETO17600.1 - 3.4 7.7 25.4 0.081 12.9 12.4 2.1 2 0 0 2 2 2 0 DivIVA protein bZIP_1 PF00170.16 ETO17600.1 - 4.2 7.4 14.3 1.3 9.0 2.0 2.9 2 0 0 2 2 2 0 bZIP transcription factor Guanylate_cyc PF00211.15 ETO17601.1 - 1.4e-12 47.3 0.0 1.9e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF565 PF04483.7 ETO17601.1 - 2.4 8.3 5.6 7 6.8 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF565) Med15 PF09606.5 ETO17602.1 - 0.0045 15.2 16.2 0.0046 15.2 11.2 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Activator_LAG-3 PF11498.3 ETO17602.1 - 0.11 11.2 17.5 0.12 11.0 12.1 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF775 PF05603.7 ETO17602.1 - 0.14 11.7 7.9 0.16 11.4 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Spt20 PF12090.3 ETO17602.1 - 0.18 11.1 7.2 0.19 11.0 5.0 1.2 1 0 0 1 1 1 0 Spt20 family PH_4 PF15404.1 ETO17602.1 - 1.1 8.7 10.8 0.81 9.1 6.7 1.4 1 1 0 1 1 1 0 Pleckstrin homology domain DUF4557 PF15101.1 ETO17602.1 - 2.1 8.1 12.4 2.4 7.9 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF4175 PF13779.1 ETO17602.1 - 3.2 5.3 17.9 3.3 5.3 12.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) BAF1_ABF1 PF04684.8 ETO17602.1 - 4.8 5.9 16.8 5.7 5.6 11.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Band_3_cyto PF07565.8 ETO17602.1 - 5.1 6.5 8.3 5.5 6.4 5.7 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain p450 PF00067.17 ETO17603.1 - 0.0026 16.3 1.4 0.0032 16.0 1.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TRP PF06011.7 ETO17603.1 - 0.025 13.1 1.2 0.04 12.5 0.8 1.4 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Neur_chan_memb PF02932.11 ETO17603.1 - 0.25 11.1 12.2 0.63 9.8 0.1 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF2457 PF10446.4 ETO17603.1 - 0.31 9.7 10.9 0.52 8.9 7.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Vfa1 PF08432.5 ETO17603.1 - 0.98 9.4 13.3 1.7 8.6 9.2 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Daxx PF03344.10 ETO17603.1 - 5.6 5.3 20.1 12 4.2 14.0 1.5 1 1 0 1 1 1 0 Daxx Family FliD_C PF07195.7 ETO17605.1 - 7.2e-27 94.2 8.4 1.2e-26 93.5 5.9 1.3 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus FliS PF02561.9 ETO17605.1 - 1.7e-22 79.5 1.6 2.2e-22 79.1 0.3 1.8 2 0 0 2 2 2 1 Flagellar protein FliS DUF3834 PF12916.2 ETO17605.1 - 0.0043 16.0 0.3 2.5 7.0 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3834) Med3 PF11593.3 ETO17607.1 - 0.0044 16.3 6.2 0.0058 15.9 4.3 1.2 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal SIT PF15330.1 ETO17607.1 - 0.11 12.6 3.2 0.3 11.2 2.2 1.8 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT BAF1_ABF1 PF04684.8 ETO17607.1 - 4.2 6.1 14.2 6.3 5.5 9.8 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Pkinase PF00069.20 ETO17610.1 - 5.3e-22 78.2 0.2 3.3e-20 72.3 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO17610.1 - 3.7e-05 22.9 0.0 6.6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 ETO17610.1 - 0.059 12.7 0.0 0.098 11.9 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kinase-like PF14531.1 ETO17610.1 - 0.064 12.2 0.5 0.98 8.3 0.1 2.1 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.9 ETO17610.1 - 0.074 12.1 0.2 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO17610.1 - 0.085 12.5 0.0 0.9 9.2 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 ETO17611.1 - 3e-72 242.9 1.3 4e-72 242.4 0.9 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO17611.1 - 7.6e-41 139.8 0.2 1.1e-40 139.3 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 ETO17611.1 - 2.7e-07 30.7 0.3 1e-06 28.9 0.0 2.1 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.1 ETO17611.1 - 1.2e-05 24.3 0.0 3.3e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETO17611.1 - 0.0001 21.4 0.1 0.00019 20.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PH_11 PF15413.1 ETO17611.1 - 0.02 15.1 0.0 0.079 13.2 0.0 2.1 1 0 0 1 1 1 0 Pleckstrin homology domain YrbL-PhoP_reg PF10707.4 ETO17611.1 - 0.021 14.1 0.3 0.047 13.0 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DUF3687 PF12459.3 ETO17612.1 - 0.0059 15.8 2.2 0.022 13.9 1.5 2.0 1 0 0 1 1 1 1 D-Ala-teichoic acid biosynthesis protein DUF515 PF04415.7 ETO17613.1 - 0.003 15.8 0.8 0.0031 15.8 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF515) DUF626 PF04776.7 ETO17613.1 - 0.14 12.4 2.3 0.7 10.2 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF626) GAF_3 PF13492.1 ETO17614.1 - 1.6e-11 44.3 0.0 2.9e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 ETO17614.1 - 6.7e-09 36.0 0.0 0.0014 18.7 0.0 2.3 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.1 ETO17614.1 - 2.5e-06 28.0 0.0 4.5e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 GAF domain Utp14 PF04615.8 ETO17615.1 - 0.0094 14.1 31.2 0.015 13.5 21.6 1.2 1 0 0 1 1 1 1 Utp14 protein TFIIF_alpha PF05793.7 ETO17615.1 - 0.026 12.9 34.8 0.046 12.0 24.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop53 PF07767.6 ETO17615.1 - 0.65 8.9 29.4 1 8.2 20.4 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Mucin PF01456.12 ETO17615.1 - 1.2 8.8 4.4 2.6 7.8 3.0 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2315 PF10231.4 ETO17616.1 - 0.016 15.0 1.2 0.026 14.3 0.8 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2315) DUF3381 PF11861.3 ETO17617.1 - 0.0063 16.0 0.5 0.011 15.2 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3381) Gal-3-0_sulfotr PF06990.6 ETO17617.1 - 0.024 13.2 0.1 0.035 12.7 0.1 1.2 1 0 0 1 1 1 0 Galactose-3-O-sulfotransferase IBN_N PF03810.14 ETO17618.1 - 1.8e-05 24.5 0.2 0.0058 16.5 0.0 2.2 2 0 0 2 2 2 2 Importin-beta N-terminal domain zf-RING_UBOX PF13445.1 ETO17618.1 - 0.043 13.5 0.4 0.49 10.1 0.0 2.5 2 1 0 2 2 2 0 RING-type zinc-finger EppA_BapA PF07268.6 ETO17618.1 - 0.044 13.4 0.2 0.079 12.6 0.1 1.4 2 0 0 2 2 2 0 Exported protein precursor (EppA/BapA) Mcp5_PH PF12814.2 ETO17619.1 - 0.0012 18.7 1.3 0.0017 18.2 0.5 1.6 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology EppA_BapA PF07268.6 ETO17619.1 - 0.018 14.7 0.2 0.035 13.7 0.1 1.5 1 0 0 1 1 1 0 Exported protein precursor (EppA/BapA) PH PF00169.24 ETO17619.1 - 0.075 13.2 1.5 0.12 12.6 0.5 1.7 2 0 0 2 2 2 0 PH domain TrbM PF07424.6 ETO17619.1 - 0.078 12.9 0.3 0.18 11.7 0.2 1.7 1 1 0 1 1 1 0 TrbM DUF4044 PF13253.1 ETO17619.1 - 5.2 6.3 5.1 10 5.3 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Asp PF00026.18 ETO17620.1 - 5.6e-39 134.2 3.3 1.4e-38 132.8 2.3 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETO17620.1 - 0.0018 18.2 0.5 0.017 15.0 0.3 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal CRM1_C PF08767.6 ETO17621.1 - 3.2e-08 32.8 0.1 4.4e-08 32.3 0.1 1.2 1 0 0 1 1 1 1 CRM1 C terminal Peptidase_M16_C PF05193.16 ETO17622.1 - 2e-10 40.6 0.1 2.6e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16 inactive domain Exonuc_VIII PF06630.6 ETO17622.1 - 0.065 12.5 0.5 0.18 11.0 0.1 1.8 2 0 0 2 2 2 0 Enterobacterial exodeoxyribonuclease VIII Aft1_OSA PF11785.3 ETO17622.1 - 0.066 13.7 2.4 0.14 12.7 1.7 1.5 1 0 0 1 1 1 0 Aft1 osmotic stress response (OSM) domain Mo25 PF08569.6 ETO17623.1 - 1.5e-56 191.8 11.4 2.2e-56 191.3 7.9 1.2 1 0 0 1 1 1 1 Mo25-like HMGL-like PF00682.14 ETO17624.1 - 3.6e-14 53.0 0.0 6.7e-14 52.1 0.0 1.4 2 0 0 2 2 2 1 HMGL-like DUF2976 PF11190.3 ETO17625.1 - 0.027 14.0 3.5 0.05 13.1 1.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2976) ORC4_C PF14629.1 ETO17626.1 - 0.042 13.2 0.1 0.057 12.7 0.1 1.3 1 1 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus MAGSP PF03082.9 ETO17626.1 - 0.045 13.1 0.0 0.051 12.9 0.0 1.1 1 0 0 1 1 1 0 Male accessory gland secretory protein TRF PF08558.5 ETO17626.1 - 0.049 12.9 0.1 0.069 12.4 0.1 1.2 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) Potyvirid-P3 PF13608.1 ETO17627.1 - 0.0011 18.1 0.2 0.0022 17.1 0.1 1.5 1 0 0 1 1 1 1 Protein P3 of Potyviral polyprotein V_ATPase_I PF01496.14 ETO17627.1 - 0.017 13.0 3.5 0.017 12.9 1.3 1.7 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family MMPL PF03176.10 ETO17627.1 - 0.048 12.3 0.4 0.072 11.7 0.3 1.1 1 0 0 1 1 1 0 MMPL family USP7_ICP0_bdg PF12436.3 ETO17628.1 - 1e-23 83.9 0.1 1.2e-23 83.6 0.1 1.2 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 FbpA PF05833.6 ETO17629.1 - 3.7e-10 38.9 0.4 5.6e-10 38.3 0.3 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) RsbRD_N PF14361.1 ETO17629.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 RsbT co-antagonist protein rsbRD N-terminal domain Vps16_C PF04840.7 ETO17630.1 - 2.5e-08 33.2 2.4 8e-07 28.3 0.3 2.0 2 0 0 2 2 2 2 Vps16, C-terminal region WD40 PF00400.27 ETO17631.1 - 4.9e-73 238.6 10.4 8.3e-12 44.5 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO17631.1 - 1.7e-15 57.2 0.0 0.00015 21.4 0.0 3.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO17631.1 - 5e-09 34.8 3.1 0.23 9.5 0.0 5.1 1 1 4 5 5 5 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO17631.1 - 8.3e-09 35.2 0.0 8.1e-07 28.7 0.0 2.7 1 1 1 2 2 2 1 PQQ-like domain PD40 PF07676.7 ETO17631.1 - 3.4e-07 29.7 7.3 2.4 7.9 0.2 6.5 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 ETO17631.1 - 5e-07 28.6 0.0 0.019 13.5 0.0 4.3 2 1 2 4 4 4 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nbas_N PF15492.1 ETO17631.1 - 7.1e-06 25.3 0.4 0.47 9.4 0.0 4.7 1 1 5 6 6 6 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 ETO17631.1 - 9.3e-06 24.1 0.3 0.15 10.3 0.0 3.1 1 1 1 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO17631.1 - 3.1e-05 22.9 3.8 1.1 7.9 0.2 5.2 2 1 3 5 5 5 1 Nup133 N terminal like Resistin PF06954.6 ETO17631.1 - 4e-05 23.7 2.6 11 6.4 0.0 5.0 3 1 2 5 5 5 0 Resistin DUF1258 PF06869.7 ETO17631.1 - 8e-05 21.8 1.8 1.6 7.7 0.0 4.1 2 1 2 4 4 4 2 Protein of unknown function (DUF1258) Hira PF07569.6 ETO17631.1 - 0.0012 18.1 1.0 4 6.5 0.0 4.5 2 2 4 6 6 6 1 TUP1-like enhancer of split Proteasome_A_N PF10584.4 ETO17631.1 - 0.0072 15.6 5.8 13 5.1 0.0 4.5 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature DUF1815 PF08844.5 ETO17631.1 - 0.057 13.0 0.0 0.64 9.6 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1815) DUF4221 PF13970.1 ETO17631.1 - 0.086 12.1 0.0 16 4.6 0.0 3.2 2 2 2 4 4 4 0 Domain of unknown function (DUF4221) Sulphotransf PF09037.5 ETO17634.1 - 0.0033 16.9 0.0 0.006 16.1 0.0 1.4 1 0 0 1 1 1 1 Stf0 sulphotransferase Ras PF00071.17 ETO17635.1 - 0.11 11.8 0.1 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Ras family DUF3136 PF11334.3 ETO17635.1 - 0.13 11.6 0.0 0.44 10.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3136) Pkinase PF00069.20 ETO17637.1 - 8e-44 149.7 6.3 6.3e-43 146.7 4.3 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO17637.1 - 1.4e-17 63.6 2.0 1.9e-13 50.0 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 ETO17637.1 - 0.0016 17.5 0.3 0.048 12.7 0.0 2.6 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family LicD PF04991.8 ETO17637.1 - 0.0026 17.8 0.4 0.0026 17.8 0.2 2.1 3 0 0 3 3 3 1 LicD family CytochromB561_N PF09786.4 ETO17638.1 - 0.17 10.3 1.7 0.15 10.4 0.7 1.3 1 1 0 1 1 1 0 Cytochrome B561, N terminal Ion_trans_N PF08412.5 ETO17638.1 - 1.5 8.1 5.7 0.26 10.6 0.2 2.3 1 1 1 2 2 2 0 Ion transport protein N-terminal DUF4282 PF14110.1 ETO17639.1 - 0.53 10.5 7.0 0.85 9.8 4.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) DUF2838 PF10998.3 ETO17639.1 - 9.5 6.1 19.6 5.6 6.9 11.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2838) Aldedh PF00171.17 ETO17640.1 - 3.6e-55 187.1 0.0 6e-55 186.4 0.0 1.3 2 0 0 2 2 2 1 Aldehyde dehydrogenase family CLASP_N PF12348.3 ETO17641.1 - 0.0014 18.0 0.0 0.0019 17.5 0.0 1.1 1 0 0 1 1 1 1 CLASP N terminal MyTH4 PF00784.12 ETO17644.1 - 4.3e-08 33.0 0.2 8.1e-08 32.2 0.0 1.5 2 0 0 2 2 2 1 MyTH4 domain RA PF00788.18 ETO17644.1 - 1.2e-05 25.6 0.0 1.8e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain FERM_N PF09379.5 ETO17644.1 - 8.1e-05 22.5 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 FERM N-terminal domain FERM_M PF00373.13 ETO17645.1 - 2.8e-13 50.1 0.4 5.3e-13 49.2 0.3 1.5 1 0 0 1 1 1 1 FERM central domain DUF2146 PF10220.4 ETO17646.1 - 0.0012 16.9 3.0 0.0016 16.5 2.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2146) MT-A70 PF05063.9 ETO17646.1 - 0.11 12.0 1.5 0.18 11.3 1.0 1.3 1 0 0 1 1 1 0 MT-A70 Pex14_N PF04695.8 ETO17646.1 - 0.87 9.6 11.9 1.6 8.7 8.2 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1635 PF07795.6 ETO17648.1 - 0.086 12.2 2.2 0.1 11.9 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) NST1 PF13945.1 ETO17649.1 - 0.15 12.1 1.3 0.14 12.2 0.9 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator BLVR PF06375.6 ETO17649.1 - 0.58 9.9 4.0 0.6 9.9 2.8 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Rsc14 PF08586.5 ETO17650.1 - 0.0037 17.7 1.3 0.023 15.1 0.3 2.1 2 0 0 2 2 2 1 RSC complex, Rsc14/Ldb7 subunit CDV3 PF15359.1 ETO17650.1 - 0.07 13.2 3.2 3.8 7.5 0.1 2.2 1 1 1 2 2 2 0 Carnitine deficiency-associated protein 3 DUF223 PF02721.9 ETO17650.1 - 0.15 12.1 1.0 0.2 11.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF223 DUF1287 PF06940.6 ETO17653.1 - 0.05 13.0 0.2 0.076 12.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1287) Corona_S2 PF01601.11 ETO17656.1 - 0.017 13.2 1.7 0.023 12.8 1.2 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Neur_chan_memb PF02932.11 ETO17656.1 - 0.06 13.2 7.6 0.35 10.7 5.2 1.9 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4448 PF14610.1 ETO17656.1 - 0.17 11.3 0.2 0.17 11.3 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4448) zf-LITAF-like PF10601.4 ETO17656.1 - 0.22 11.4 4.6 0.39 10.6 3.2 1.3 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain Shisa PF13908.1 ETO17656.1 - 0.57 10.3 23.1 0.075 13.2 10.0 2.8 1 1 0 2 2 2 0 Wnt and FGF inhibitory regulator FAM163 PF15069.1 ETO17656.1 - 2.3 8.7 12.8 34 4.9 8.9 2.7 1 1 0 1 1 1 0 FAM163 family Macoilin PF09726.4 ETO17656.1 - 3.1 5.9 15.3 3.9 5.6 10.6 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF605 PF04652.11 ETO17656.1 - 5.7 6.2 27.8 8.4 5.6 19.3 1.2 1 0 0 1 1 1 0 Vta1 like GlcNAc PF11397.3 ETO17657.1 - 1.3e-26 93.6 0.0 1.7e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) DUF912 PF06024.7 ETO17660.1 - 0.0058 16.6 1.4 1.2 9.2 0.0 3.0 3 1 0 3 3 3 2 Nucleopolyhedrovirus protein of unknown function (DUF912) Bac_export_2 PF01312.14 ETO17660.1 - 0.074 11.9 0.1 0.19 10.6 0.0 1.6 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family DUF2909 PF11137.3 ETO17660.1 - 1.3 8.7 9.2 4.3 7.1 1.5 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF2909) Tic20 PF09685.5 ETO17660.1 - 3.1 7.8 6.7 13 5.8 4.7 2.3 1 1 0 1 1 1 0 Tic20-like protein RRM_1 PF00076.17 ETO17661.1 - 7.7e-09 35.0 0.0 0.0082 15.7 0.0 3.6 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO17661.1 - 5.1e-05 23.1 1.0 0.71 9.8 0.1 3.8 3 1 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO17661.1 - 0.00089 19.0 0.0 4.3 7.2 0.0 3.6 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc PF12871.2 ETO17662.1 - 0.019 15.5 8.4 0.019 15.5 5.8 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Transformer PF06495.6 ETO17662.1 - 0.048 13.5 12.6 0.13 12.1 8.7 1.7 1 0 0 1 1 1 0 Fruit fly transformer protein Corona_nucleoca PF00937.13 ETO17662.1 - 2.7 6.8 23.0 0.024 13.6 6.7 2.2 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein PGM_PMM_IV PF00408.15 ETO17663.1 - 3.4e-09 36.5 0.0 5.5e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain FtsQ PF03799.10 ETO17663.1 - 0.04 14.1 0.0 0.057 13.6 0.0 1.2 1 0 0 1 1 1 0 Cell division protein FtsQ zf-met2 PF12907.2 ETO17663.1 - 0.18 11.7 0.4 0.4 10.6 0.1 1.7 2 0 0 2 2 2 0 Zinc-binding DUF2450 PF10475.4 ETO17664.1 - 5.9e-19 68.0 14.5 2.4e-17 62.7 10.1 2.1 1 1 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) MerB PF03243.10 ETO17664.1 - 0.017 14.9 0.2 0.03 14.1 0.2 1.4 1 0 0 1 1 1 0 Alkylmercury lyase F-box-like_2 PF13013.1 ETO17664.1 - 0.063 13.0 0.4 0.19 11.4 0.1 1.8 1 1 1 2 2 2 0 F-box-like domain Ran_BP1 PF00638.13 ETO17665.1 - 0.0041 17.1 0.7 0.0041 17.1 0.5 2.0 2 0 0 2 2 2 1 RanBP1 domain KH_5 PF13184.1 ETO17665.1 - 0.035 13.8 1.0 0.075 12.8 0.5 1.7 2 0 0 2 2 2 0 NusA-like KH domain DUF3439 PF11921.3 ETO17665.1 - 1.7 8.3 6.0 6.3 6.5 3.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF3810 PF12725.2 ETO17666.1 - 0.14 11.0 1.6 0.18 10.7 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) Spb1_C PF07780.7 ETO17667.1 - 3e-49 167.4 16.5 4e-49 167.0 11.4 1.1 1 0 0 1 1 1 1 Spb1 C-terminal domain Dicty_REP PF05086.7 ETO17668.1 - 0.19 9.4 16.3 0.014 13.2 1.4 2.1 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein TRP PF06011.7 ETO17669.1 - 0.0074 14.9 4.6 0.019 13.5 0.1 2.0 2 0 0 2 2 2 2 Transient receptor potential (TRP) ion channel Scs3p PF10261.4 ETO17669.1 - 1.1 8.2 6.2 0.2 10.6 0.9 2.0 2 0 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM CAF-1_p150 PF11600.3 ETO17671.1 - 0.23 10.8 36.4 0.29 10.4 25.2 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal HSP90 PF00183.13 ETO17671.1 - 2 6.7 16.0 2.6 6.3 11.1 1.1 1 0 0 1 1 1 0 Hsp90 protein PBP_sp32 PF07222.7 ETO17671.1 - 2.4 7.2 18.2 3.2 6.8 12.6 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Raftlin PF15250.1 ETO17671.1 - 2.9 6.3 12.6 3.4 6.0 8.7 1.1 1 0 0 1 1 1 0 Raftlin FLO_LFY PF01698.11 ETO17671.1 - 3.7 6.2 16.3 4.1 6.1 11.3 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Paf1 PF03985.8 ETO17671.1 - 5.6 5.5 22.6 7 5.2 15.7 1.1 1 0 0 1 1 1 0 Paf1 NARP1 PF12569.3 ETO17671.1 - 6 5.4 19.6 7.6 5.1 13.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 XRN_N PF03159.13 ETO17671.1 - 7.4 5.8 7.9 11 5.3 5.5 1.2 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus Pkinase PF00069.20 ETO17672.1 - 2.1e-32 112.2 1.3 2.5e-32 112.0 0.9 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO17672.1 - 2.8e-17 62.6 1.0 3e-17 62.5 0.7 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase FWWh PF14922.1 ETO17673.1 - 1.1e-11 44.4 4.0 1.4e-11 44.1 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function UPF0118 PF01594.11 ETO17674.1 - 0.17 10.8 2.4 0.62 8.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF20 Dapper PF15268.1 ETO17674.1 - 0.62 8.7 18.4 0.77 8.4 12.7 1.1 1 0 0 1 1 1 0 Dapper AAA PF00004.24 ETO17675.1 - 0.057 13.6 0.3 0.29 11.3 0.1 2.1 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF4551 PF15087.1 ETO17676.1 - 0.0093 14.3 1.1 0.011 14.1 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4551) Utp14 PF04615.8 ETO17678.1 - 0.22 9.6 49.6 0.26 9.3 34.4 1.0 1 0 0 1 1 1 0 Utp14 protein PPV_E1_N PF00524.13 ETO17679.1 - 0.38 10.9 6.1 0.19 11.9 2.3 1.8 2 0 0 2 2 2 0 E1 Protein, N terminal domain WD40 PF00400.27 ETO17681.1 - 1.6e-56 186.2 17.2 1.1e-11 44.0 0.2 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO17681.1 - 5.6e-13 47.8 5.4 0.011 13.9 0.1 6.0 2 2 3 6 6 6 6 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO17681.1 - 0.0064 15.2 8.1 0.55 8.9 0.8 4.2 2 2 1 4 4 4 3 Nup133 N terminal like DUF1340 PF07067.6 ETO17684.1 - 0.018 14.1 0.4 0.018 14.1 0.3 1.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1340) PMD PF10536.4 ETO17684.1 - 0.22 10.4 2.9 3.3 6.6 0.5 2.1 1 1 0 2 2 2 0 Plant mobile domain RsgI_N PF12791.2 ETO17685.1 - 0.011 15.3 0.4 0.021 14.4 0.3 1.5 1 0 0 1 1 1 0 Anti-sigma factor N-terminus DUF2457 PF10446.4 ETO17685.1 - 0.05 12.3 22.6 0.21 10.2 14.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Vfa1 PF08432.5 ETO17685.1 - 0.071 13.1 10.9 0.96 9.4 3.1 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 ETO17685.1 - 0.99 7.3 16.4 3.4 5.5 7.7 2.2 2 0 0 2 2 2 0 CDC45-like protein Methyltransf_12 PF08242.7 ETO17685.1 - 1.7 9.1 9.5 1.3 9.5 0.2 2.3 2 0 0 2 2 2 0 Methyltransferase domain DUF2796 PF10986.3 ETO17685.1 - 3.7 7.5 24.7 3.5 7.5 7.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) Sporozoite_P67 PF05642.6 ETO17685.1 - 5.2 4.8 9.4 7.8 4.2 6.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AAA_21 PF13304.1 ETO17686.1 - 0.27 11.1 9.5 0.37 10.7 6.6 1.1 1 0 0 1 1 1 0 AAA domain EphA2_TM PF14575.1 ETO17686.1 - 0.97 9.8 2.9 3.9 7.9 1.4 2.3 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain CSD PF00313.17 ETO17688.1 - 1.3e-08 34.5 0.1 3.3e-08 33.1 0.1 1.7 2 0 0 2 2 2 1 'Cold-shock' DNA-binding domain SOG2 PF10428.4 ETO17688.1 - 0.031 12.9 1.8 0.052 12.1 1.2 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Kei1 PF08552.6 ETO17689.1 - 0.0032 17.1 0.2 0.004 16.8 0.1 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 zf-DHHC PF01529.15 ETO17689.1 - 8.6 5.7 7.5 3.4 7.0 3.5 1.5 1 1 0 1 1 1 0 DHHC palmitoyltransferase Exo_endo_phos PF03372.18 ETO17690.1 - 2.8e-13 50.3 0.0 7.6e-13 48.9 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 ETO17690.1 - 0.016 14.7 0.0 0.076 12.6 0.0 2.2 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Misat_Tub_SegII PF10644.4 ETO17690.1 - 0.84 9.7 0.0 0.84 9.7 0.0 2.7 3 0 0 3 3 3 0 Misato Segment II tubulin-like domain CPSF73-100_C PF11718.3 ETO17690.1 - 3.4 6.9 9.9 2 7.6 4.0 2.2 1 1 1 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term CreD PF06123.7 ETO17691.1 - 0.035 12.6 0.9 0.045 12.2 0.0 1.6 2 0 0 2 2 2 0 Inner membrane protein CreD PH PF00169.24 ETO17692.1 - 0.0001 22.4 0.2 0.0001 22.4 0.1 2.6 2 1 0 2 2 2 1 PH domain Mito_fiss_reg PF05308.6 ETO17693.1 - 0.021 14.1 8.3 0.047 13.0 5.8 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator DSPc PF00782.15 ETO17694.1 - 4.7e-30 103.8 0.1 3.4e-29 101.0 0.0 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 ETO17694.1 - 2.6e-05 23.6 0.2 7.9e-05 22.0 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 ETO17694.1 - 0.00063 20.0 0.1 0.0066 16.7 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain PTPlike_phytase PF14566.1 ETO17694.1 - 0.0022 18.0 0.0 0.004 17.2 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate ADIP PF11559.3 ETO17695.1 - 7.6e-07 29.1 10.5 3.8e-05 23.6 2.6 2.2 2 0 0 2 2 2 2 Afadin- and alpha -actinin-Binding DUF3520 PF12034.3 ETO17695.1 - 0.0048 17.0 3.7 0.0067 16.5 2.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3520) DUF904 PF06005.7 ETO17695.1 - 0.0055 16.9 11.0 0.0066 16.7 5.7 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF904) HALZ PF02183.13 ETO17695.1 - 0.0082 15.8 4.5 0.051 13.2 3.1 2.3 1 1 0 1 1 1 1 Homeobox associated leucine zipper IncA PF04156.9 ETO17695.1 - 0.019 14.5 9.1 0.029 13.9 6.1 1.6 1 1 0 1 1 1 0 IncA protein DUF3606 PF12244.3 ETO17695.1 - 0.03 13.9 0.0 0.069 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) DUF2857 PF11198.3 ETO17695.1 - 0.04 13.4 1.2 3.2 7.2 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2857) DUF1664 PF07889.7 ETO17695.1 - 0.075 12.8 2.6 0.09 12.5 1.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Shugoshin_N PF07558.6 ETO17695.1 - 0.11 12.2 6.1 2 8.1 0.6 2.6 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region ApoO PF09769.4 ETO17695.1 - 0.14 11.9 4.1 0.35 10.5 2.8 1.8 1 1 0 1 1 1 0 Apolipoprotein O FlaC_arch PF05377.6 ETO17695.1 - 0.15 11.9 4.5 2.1 8.3 0.2 3.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF4201 PF13870.1 ETO17695.1 - 0.3 10.4 12.3 0.015 14.7 4.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) APG6 PF04111.7 ETO17695.1 - 0.42 9.6 11.0 0.47 9.4 7.3 1.3 1 1 0 1 1 1 0 Autophagy protein Apg6 Reo_sigmaC PF04582.7 ETO17695.1 - 0.43 9.6 5.9 0.53 9.4 4.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein RyR PF02026.11 ETO17695.1 - 0.54 10.3 3.8 0.15 12.1 0.4 2.1 2 1 0 2 2 2 0 RyR domain Mod_r PF07200.8 ETO17695.1 - 0.6 10.0 12.5 0.1 12.5 4.5 2.4 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Cortex-I_coil PF09304.5 ETO17695.1 - 0.72 9.9 11.5 0.14 12.2 4.1 2.2 1 1 2 3 3 3 0 Cortexillin I, coiled coil Corona_nucleoca PF00937.13 ETO17695.1 - 0.81 8.5 9.0 1.3 7.8 3.4 2.0 1 1 1 2 2 2 0 Coronavirus nucleocapsid protein Med9 PF07544.8 ETO17695.1 - 0.87 9.3 6.2 0.4 10.4 1.3 2.6 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Syntaxin-6_N PF09177.6 ETO17695.1 - 2.5 8.5 9.0 3.8 7.9 3.7 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal V_ATPase_I PF01496.14 ETO17695.1 - 4.2 5.0 7.9 4.4 5.0 5.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.4 ETO17695.1 - 5.8 6.7 19.2 34 4.3 13.3 2.0 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EF-hand_1 PF00036.27 ETO17697.1 - 8.1e-36 118.5 21.1 2.2e-10 39.0 1.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 ETO17697.1 - 4.6e-32 109.9 12.3 8.8e-18 64.2 1.5 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO17697.1 - 6.7e-27 90.9 14.2 1.9e-07 30.3 0.0 4.7 3 1 2 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 ETO17697.1 - 1.2e-26 90.7 16.5 2.6e-09 36.0 0.3 4.7 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 ETO17697.1 - 2.6e-25 87.7 21.0 1.5e-12 46.9 2.3 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.1 ETO17697.1 - 2.4e-13 49.7 0.7 9.8e-06 25.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 ETO17697.1 - 1.9e-10 40.7 2.0 0.00014 21.8 0.1 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 ETO17697.1 - 3.3e-08 33.1 8.2 0.00036 20.2 0.2 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand TerB PF05099.8 ETO17697.1 - 6.2e-07 29.2 0.8 0.012 15.3 0.0 3.0 2 1 1 3 3 3 2 Tellurite resistance protein TerB EF-hand_10 PF14788.1 ETO17697.1 - 0.00065 19.3 5.9 0.013 15.1 1.0 2.6 2 0 0 2 2 2 1 EF hand Caleosin PF05042.8 ETO17697.1 - 0.0022 17.5 0.1 0.11 12.0 0.0 2.4 2 1 0 2 2 2 1 Caleosin related protein SpoVIF PF14069.1 ETO17697.1 - 0.07 12.8 0.1 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Stage VI sporulation protein F UPF0154 PF03672.8 ETO17697.1 - 0.12 11.9 0.1 29 4.3 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) DUF1521 PF07481.6 ETO17697.1 - 0.17 11.5 6.3 3.3 7.3 0.1 3.3 3 1 0 3 3 3 0 Domain of Unknown Function (DUF1521) BCNT PF07572.7 ETO17697.1 - 0.36 10.7 2.4 0.94 9.4 0.1 2.5 3 0 0 3 3 3 0 Bucentaur or craniofacial development UPF0158 PF03682.8 ETO17697.1 - 0.45 10.1 4.0 0.38 10.3 0.3 2.0 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0158) Adaptin_binding PF10199.4 ETO17697.1 - 3.9 7.7 9.9 4.2 7.6 3.4 2.3 1 1 1 2 2 2 0 Alpha and gamma adaptin binding protein p34 DUF3525 PF12039.3 ETO17698.1 - 0.22 10.0 1.3 0.26 9.7 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) AAA_4 PF04326.9 ETO17699.1 - 6.3e-09 36.0 0.0 1.9e-08 34.5 0.0 1.9 1 0 0 1 1 1 1 Divergent AAA domain DHC_N2 PF08393.8 ETO17700.1 - 1.5e-106 356.3 38.4 1.4e-68 231.2 5.5 4.7 4 2 2 6 6 6 3 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 ETO17700.1 - 1.2e-24 87.1 0.1 2.5e-24 86.0 0.1 1.5 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA PF00004.24 ETO17700.1 - 0.01 16.0 0.3 0.055 13.6 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Plasmid_RAQPRD PF09686.5 ETO17700.1 - 0.011 15.8 0.4 0.2 11.7 0.0 3.4 4 0 0 4 4 4 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF4476 PF14771.1 ETO17700.1 - 0.013 15.4 0.9 0.013 15.4 0.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4476) HsbA PF12296.3 ETO17700.1 - 0.022 14.5 0.1 0.17 11.7 0.0 2.7 2 0 0 2 2 2 0 Hydrophobic surface binding protein A AAA_17 PF13207.1 ETO17700.1 - 0.1 13.4 0.1 0.94 10.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 ETO17700.1 - 0.11 12.2 0.1 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_6 PF12774.2 ETO17701.1 - 1.1e-64 218.1 0.1 2.8e-64 216.8 0.0 1.7 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 ETO17701.1 - 2.7e-05 23.9 0.0 0.05 13.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) DUF853 PF05872.7 ETO17701.1 - 0.025 12.9 0.0 0.036 12.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Use1 PF09753.4 ETO17703.1 - 0.048 13.1 0.1 0.077 12.4 0.1 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 GAS PF13851.1 ETO17703.1 - 0.057 12.6 0.3 0.39 9.8 0.0 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding WBP-1 PF11669.3 ETO17704.1 - 1.2 9.1 8.0 5.4 7.1 0.7 2.5 2 0 0 2 2 2 0 WW domain-binding protein 1 G-alpha PF00503.15 ETO17705.1 - 3.8e-12 45.6 8.5 1e-11 44.1 5.9 1.8 1 1 0 1 1 1 1 G-protein alpha subunit Ribosomal_S13 PF00416.17 ETO17706.1 - 0.19 12.2 3.3 1 9.8 2.3 2.4 1 1 0 1 1 1 0 Ribosomal protein S13/S18 DUF334 PF03904.8 ETO17706.1 - 0.24 10.6 7.2 0.032 13.5 1.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF334) Latarcin PF10279.4 ETO17706.1 - 1.2 9.3 4.3 23 5.2 0.2 3.5 3 0 0 3 3 3 0 Latarcin precursor Tropomyosin_1 PF12718.2 ETO17708.1 - 0.0031 17.3 8.0 0.011 15.5 5.5 1.8 1 1 0 1 1 1 1 Tropomyosin like TMF_TATA_bd PF12325.3 ETO17708.1 - 0.0045 16.7 12.1 0.0082 15.8 1.7 2.2 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding DUF1465 PF07323.7 ETO17708.1 - 0.0085 15.6 0.7 0.0085 15.6 0.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1465) PspB PF06667.7 ETO17708.1 - 0.018 14.9 5.2 0.31 11.0 0.2 2.5 2 1 0 2 2 2 0 Phage shock protein B Fib_alpha PF08702.5 ETO17708.1 - 0.026 14.6 12.7 0.042 13.9 8.7 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF3053 PF11254.3 ETO17708.1 - 0.12 11.6 5.6 0.041 13.1 1.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3053) HrpB7 PF09486.5 ETO17708.1 - 0.12 12.2 5.7 0.87 9.4 3.9 2.0 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) ATG16 PF08614.6 ETO17708.1 - 0.21 11.3 14.4 0.33 10.7 9.6 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.3 ETO17708.1 - 0.26 11.1 7.7 0.54 10.1 1.1 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CENP-Q PF13094.1 ETO17708.1 - 0.34 10.9 10.7 3.1 7.7 3.6 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit YjcZ PF13990.1 ETO17708.1 - 0.44 9.6 8.3 0.14 11.2 3.7 1.6 1 1 1 2 2 2 0 YjcZ-like protein Exonuc_VII_L PF02601.10 ETO17708.1 - 0.73 8.9 12.4 0.9 8.6 8.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit KLRAQ PF10205.4 ETO17708.1 - 1.1 9.3 13.8 1.1 9.3 3.7 2.5 1 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein Adeno_PIX PF03955.9 ETO17708.1 - 1.5 9.3 4.0 19 5.8 0.1 2.2 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Prefoldin_2 PF01920.15 ETO17708.1 - 2.4 7.9 13.1 4.3 7.1 0.3 3.1 2 1 1 3 3 3 0 Prefoldin subunit Microtub_assoc PF07989.6 ETO17708.1 - 2.5 7.9 8.1 1.9 8.4 0.3 2.9 2 1 1 3 3 3 0 Microtubule associated Sec8_exocyst PF04048.9 ETO17708.1 - 2.8 7.5 12.8 3.2 7.3 4.9 2.1 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain bZIP_1 PF00170.16 ETO17708.1 - 4.4 7.3 9.3 13 5.8 0.9 3.3 2 1 1 3 3 3 0 bZIP transcription factor Cep57_CLD_2 PF14197.1 ETO17708.1 - 4.6 7.2 13.5 5.9 6.9 3.2 3.0 3 1 0 3 3 2 0 Centrosome localisation domain of PPC89 EMP24_GP25L PF01105.19 ETO17708.1 - 4.6 6.9 11.5 0.73 9.5 3.7 2.0 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF724 PF05266.9 ETO17708.1 - 5.5 6.5 13.5 1.1 8.7 1.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF724) DUF641 PF04859.7 ETO17708.1 - 5.7 6.7 12.2 0.61 9.8 2.8 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF745 PF05335.8 ETO17708.1 - 6.9 6.1 9.2 10 5.5 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF342 PF03961.8 ETO17708.1 - 8.3 4.6 10.0 26 3.0 6.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Apo-CIII PF05778.7 ETO17709.1 - 0.084 12.2 0.1 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) Histone_HNS PF00816.16 ETO17711.1 - 0.048 14.1 5.1 0.048 14.1 3.5 2.8 2 1 0 2 2 2 0 H-NS histone family Mnd1 PF03962.10 ETO17711.1 - 0.13 11.9 32.2 0.46 10.1 9.8 2.1 2 0 0 2 2 2 0 Mnd1 family Allexi_40kDa PF05549.6 ETO17711.1 - 0.23 10.6 13.9 1.3 8.2 0.9 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF1192 PF06698.6 ETO17711.1 - 0.31 10.8 12.6 1.6 8.5 0.7 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Muted PF14942.1 ETO17711.1 - 0.77 9.6 31.3 0.38 10.6 6.5 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Reo_sigmaC PF04582.7 ETO17711.1 - 1.2 8.2 8.0 3.3 6.7 0.4 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein SID-1_RNA_chan PF13965.1 ETO17711.1 - 1.4 7.0 11.7 0.3 9.1 5.7 1.4 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 AAA_13 PF13166.1 ETO17711.1 - 1.8 6.9 27.2 2.8 6.2 18.8 1.4 1 1 0 1 1 1 0 AAA domain Phage_lysozyme PF00959.14 ETO17711.1 - 3.1 8.1 6.0 11 6.3 0.1 2.7 2 1 0 2 2 2 0 Phage lysozyme Baculo_p24 PF05073.7 ETO17711.1 - 3.1 7.3 23.2 0.017 14.6 4.9 2.2 1 1 1 2 2 2 0 Baculovirus P24 capsid protein DNA_ligase_A_N PF04675.9 ETO17711.1 - 3.6 7.3 10.0 0.16 11.7 2.6 1.9 2 1 0 2 2 2 0 DNA ligase N terminus FlgN PF05130.7 ETO17711.1 - 4.8 7.4 33.3 0.14 12.4 3.9 3.2 3 0 0 3 3 3 0 FlgN protein APG6 PF04111.7 ETO17711.1 - 8.2 5.3 36.8 0.67 8.9 8.1 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF3573 PF12097.3 ETO17711.1 - 8.5 4.8 17.6 0.073 11.6 5.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) Glutaminase PF04960.10 ETO17711.1 - 8.7 5.2 6.1 0.98 8.3 0.5 1.9 2 0 0 2 2 2 0 Glutaminase DSPc PF00782.15 ETO17712.1 - 6.8e-31 106.6 1.4 1.5e-30 105.4 0.0 2.2 2 1 1 3 3 3 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 ETO17712.1 - 1.1e-06 28.9 0.5 0.00026 21.2 0.1 2.7 2 1 0 2 2 2 2 Rhodanese-like domain PTPlike_phytase PF14566.1 ETO17712.1 - 1.4e-05 25.1 0.0 3.2e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Ribonuc_L-PSP PF01042.16 ETO17712.1 - 0.012 15.3 0.1 0.021 14.5 0.1 1.4 1 0 0 1 1 1 0 Endoribonuclease L-PSP DUF2630 PF10944.3 ETO17712.1 - 0.033 14.2 1.2 0.13 12.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2630) Spt20 PF12090.3 ETO17714.1 - 0.0062 15.8 7.9 0.0077 15.6 5.5 1.2 1 0 0 1 1 1 1 Spt20 family Tyrosinase PF00264.15 ETO17714.1 - 0.057 13.5 7.7 0.074 13.1 5.3 1.2 1 0 0 1 1 1 0 Common central domain of tyrosinase DUF2512 PF10710.4 ETO17714.1 - 0.089 12.2 1.3 0.17 11.3 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) Daxx PF03344.10 ETO17714.1 - 0.11 10.9 21.7 0.14 10.6 15.1 1.1 1 0 0 1 1 1 0 Daxx Family Prog_receptor PF02161.10 ETO17714.1 - 0.34 9.6 8.8 0.4 9.4 6.1 1.2 1 0 0 1 1 1 0 Progesterone receptor DUF4628 PF15429.1 ETO17714.1 - 0.37 10.1 11.1 0.48 9.8 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) DUF3573 PF12097.3 ETO17714.1 - 0.55 8.7 6.3 0.65 8.5 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Ycf1 PF05758.7 ETO17714.1 - 0.77 7.3 18.0 0.84 7.2 12.5 1.0 1 0 0 1 1 1 0 Ycf1 Neur_chan_memb PF02932.11 ETO17714.1 - 2 8.2 7.2 2.4 7.9 5.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Med19 PF10278.4 ETO17714.1 - 2.3 7.8 17.1 4.5 6.9 1.7 2.1 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 DUF3675 PF12428.3 ETO17714.1 - 2.4 8.4 5.6 0.77 10.0 1.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3675) CT47 PF15623.1 ETO17714.1 - 2.7 7.6 19.4 3.9 7.1 13.5 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 Paramyxo_ncap PF00973.14 ETO17714.1 - 2.8 6.5 13.6 3.3 6.3 9.4 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein FYDLN_acid PF09538.5 ETO17714.1 - 5.8 7.5 23.6 1.6e+02 2.8 16.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF740 PF05340.7 ETO17714.1 - 7.1 4.8 14.6 8.9 4.5 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Serinc PF03348.10 ETO17714.1 - 9.2 4.8 7.8 13 4.3 5.4 1.5 1 1 0 1 1 1 0 Serine incorporator (Serinc) DUF3439 PF11921.3 ETO17717.1 - 0.18 11.5 2.2 0.44 10.3 1.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PgaD PF13994.1 ETO17717.1 - 1.5 8.3 7.9 2.9 7.3 2.1 2.3 1 1 1 2 2 2 0 PgaD-like protein Peptidase_S64 PF08192.6 ETO17718.1 - 1.1 7.5 10.8 1.2 7.3 7.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF605 PF04652.11 ETO17718.1 - 1.3 8.3 14.6 1.4 8.2 10.1 1.1 1 0 0 1 1 1 0 Vta1 like MIP-T3 PF10243.4 ETO17718.1 - 2 6.7 15.2 2.2 6.6 10.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Macoilin PF09726.4 ETO17718.1 - 3.6 5.7 14.8 4.3 5.5 10.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Guanylate_cyc PF00211.15 ETO17719.1 - 1.2e-09 37.8 0.0 1e-08 34.7 0.0 2.0 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Asp-Al_Ex PF06826.7 ETO17719.1 - 0.024 14.1 0.3 0.037 13.5 0.2 1.2 1 0 0 1 1 1 0 Predicted Permease Membrane Region VARLMGL PF14383.1 ETO17719.1 - 0.1 11.8 0.2 0.17 11.0 0.1 1.4 1 0 0 1 1 1 0 DUF761-associated sequence motif TPR_19 PF14559.1 ETO17721.1 - 1.7e-09 37.8 15.5 0.00032 20.9 0.1 6.8 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO17721.1 - 2.1e-07 30.3 18.6 0.24 11.4 0.1 9.6 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO17721.1 - 2.9e-07 30.1 5.0 0.034 14.3 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO17721.1 - 6.6e-07 29.8 2.2 4.2 8.1 0.0 7.2 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO17721.1 - 1.5e-06 27.7 21.3 0.01 15.4 0.1 7.7 7 2 3 10 10 10 3 TPR repeat TPR_6 PF13174.1 ETO17721.1 - 5.6e-05 23.3 11.6 1.4 9.5 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO17721.1 - 0.00034 20.4 0.2 0.54 10.2 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO17721.1 - 0.00036 20.1 22.4 2.5 8.0 0.5 8.1 8 1 0 8 8 7 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO17721.1 - 0.0012 18.9 46.2 0.01 15.9 0.6 8.1 6 1 2 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 ETO17721.1 - 0.0068 16.9 0.6 88 4.1 0.0 6.0 8 1 1 9 9 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETO17721.1 - 0.029 13.9 16.3 24 4.7 0.0 8.6 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETO17721.1 - 0.33 10.9 20.8 0.71 9.8 0.2 6.3 7 2 2 9 9 9 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETO17722.1 - 4.1e-11 42.4 0.8 0.94 10.3 0.1 8.0 9 2 1 10 10 7 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO17722.1 - 1.2e-09 37.3 13.4 0.035 14.0 0.0 8.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO17722.1 - 6.4e-09 35.6 14.6 0.017 15.0 0.7 6.6 5 2 3 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO17722.1 - 2.1e-08 33.3 2.4 0.0027 17.3 0.0 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO17722.1 - 2.1e-08 34.1 31.7 0.02 15.0 0.0 6.7 3 2 3 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 ETO17722.1 - 2.4e-08 33.4 15.8 8.2e-05 22.1 0.0 6.7 5 2 1 6 6 6 2 TPR repeat TPR_19 PF14559.1 ETO17722.1 - 4.9e-08 33.2 14.8 0.47 10.8 0.3 7.4 5 3 3 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO17722.1 - 8.6e-08 32.6 6.0 0.13 12.9 0.1 6.6 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO17722.1 - 4.3e-06 26.8 7.4 1.5 9.4 0.0 7.7 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO17722.1 - 0.00014 21.3 11.5 0.52 10.0 0.0 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO17722.1 - 0.0083 16.2 0.7 8.1 6.9 0.0 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat PPR_3 PF13812.1 ETO17722.1 - 0.014 15.6 0.1 0.59 10.5 0.0 3.9 4 0 0 4 4 2 0 Pentatricopeptide repeat domain TPR_8 PF13181.1 ETO17722.1 - 0.051 13.3 13.4 2.1 8.3 0.0 7.5 9 0 0 9 9 9 0 Tetratricopeptide repeat SurA_N_2 PF13623.1 ETO17722.1 - 0.86 9.5 3.8 18 5.2 0.4 3.1 2 1 0 3 3 3 0 SurA N-terminal domain WD40 PF00400.27 ETO17723.1 - 0.0043 16.8 0.3 0.0043 16.8 0.2 3.5 4 0 0 4 4 4 1 WD domain, G-beta repeat ERG4_ERG24 PF01222.12 ETO17723.1 - 0.011 14.2 0.1 0.014 13.9 0.1 1.2 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family HNOBA PF07701.9 ETO17723.1 - 0.058 12.5 0.0 0.084 12.0 0.0 1.2 1 0 0 1 1 1 0 Heme NO binding associated RNase_PH PF01138.16 ETO17724.1 - 9.2e-26 90.7 0.4 1.4e-25 90.1 0.3 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 ETO17724.1 - 0.00059 19.7 0.6 0.0019 18.1 0.4 2.0 1 1 0 1 1 1 1 3' exoribonuclease family, domain 2 RGS PF00615.14 ETO17725.1 - 0.0022 18.0 2.0 0.011 15.8 1.4 2.2 1 1 0 1 1 1 1 Regulator of G protein signaling domain Acyl-CoA_dh_1 PF00441.19 ETO17726.1 - 3.2e-39 134.4 0.2 3.9e-39 134.1 0.2 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 ETO17726.1 - 4.9e-12 46.2 0.1 6.4e-12 45.8 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Helicase_C PF00271.26 ETO17727.1 - 9.5e-26 89.4 0.1 1.9e-25 88.5 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETO17727.1 - 4.1e-07 29.6 0.0 7.5e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4639 PF15479.1 ETO17728.1 - 0.028 13.0 0.8 0.032 12.9 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4639) Marek_SORF3 PF07153.6 ETO17728.1 - 0.068 11.8 1.8 0.079 11.6 1.2 1.2 1 0 0 1 1 1 0 Marek's disease-like virus SORF3 protein SURF6 PF04935.7 ETO17728.1 - 0.16 11.2 13.4 0.19 11.0 9.3 1.1 1 0 0 1 1 1 0 Surfeit locus protein 6 DUF2890 PF11081.3 ETO17728.1 - 0.26 11.3 16.5 0.33 10.9 11.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Daxx PF03344.10 ETO17728.1 - 0.43 8.9 21.8 0.52 8.7 15.1 1.1 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 ETO17728.1 - 0.53 9.3 21.7 0.69 8.9 15.1 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 ETO17728.1 - 1.3 6.8 23.1 1.4 6.7 16.0 1.0 1 0 0 1 1 1 0 Nop14-like family Peptidase_C37 PF05416.7 ETO17728.1 - 1.9 6.7 7.3 2.1 6.5 5.0 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase DUF605 PF04652.11 ETO17728.1 - 1.9 7.8 13.9 2.3 7.5 9.6 1.1 1 0 0 1 1 1 0 Vta1 like Lin-8 PF03353.10 ETO17728.1 - 4.9 6.3 14.6 5.5 6.1 10.1 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist G-7-MTase PF12803.2 ETO17728.1 - 6.4 5.8 6.4 7.7 5.5 4.4 1.1 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) Asp-B-Hydro_N PF05279.6 ETO17728.1 - 8.5 6.1 18.3 10 5.8 12.7 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Peptidase_S64 PF08192.6 ETO17728.1 - 8.5 4.5 11.9 9.9 4.3 8.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 Harakiri PF15196.1 ETO17729.1 - 0.092 12.9 0.3 0.2 11.8 0.2 1.6 1 0 0 1 1 1 0 Activator of apoptosis harakiri GRP PF07172.6 ETO17729.1 - 7.5 7.1 25.0 3.2 8.2 14.9 2.2 2 0 0 2 2 2 0 Glycine rich protein family DUF1312 PF07009.6 ETO17730.1 - 0.12 12.2 3.3 0.46 10.3 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1312) Ras PF00071.17 ETO17731.1 - 3.8e-31 107.6 0.8 4.5e-31 107.4 0.5 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO17731.1 - 2.2e-14 53.9 0.1 3.7e-14 53.2 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 ETO17731.1 - 0.0002 20.8 0.0 0.00024 20.5 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 ETO17731.1 - 0.00093 18.4 0.1 0.001 18.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Imm1 PF14430.1 ETO17731.1 - 0.0011 19.1 0.1 0.0018 18.4 0.0 1.3 1 1 0 1 1 1 1 Immunity protein Imm1 RE_TdeIII PF09520.5 ETO17731.1 - 0.027 13.7 0.1 0.03 13.6 0.1 1.3 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII Fimbrial_PilY2 PF14481.1 ETO17731.1 - 0.048 13.0 0.0 0.066 12.6 0.0 1.4 1 1 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 CN_hydrolase PF00795.17 ETO17734.1 - 2.2e-10 40.2 0.0 3.3e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Transposase_28 PF04195.7 ETO17734.1 - 0.023 13.9 0.1 0.034 13.4 0.1 1.2 1 0 0 1 1 1 0 Putative gypsy type transposon Bestrophin PF01062.16 ETO17735.1 - 0.16 10.8 0.4 0.23 10.3 0.2 1.1 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel Daxx PF03344.10 ETO17736.1 - 0.063 11.7 29.6 0.067 11.6 20.5 1.0 1 0 0 1 1 1 0 Daxx Family Mpp10 PF04006.7 ETO17736.1 - 0.21 9.8 31.7 0.23 9.7 22.0 1.0 1 0 0 1 1 1 0 Mpp10 protein SpoIIIAH PF12685.2 ETO17736.1 - 7.9 5.9 11.6 10 5.5 8.1 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Phage_P2_GpE PF06528.7 ETO17737.1 - 0.041 13.3 0.5 0.093 12.1 0.0 1.8 2 0 0 2 2 2 0 Phage P2 GpE Cmyb_C PF09316.5 ETO17737.1 - 0.12 11.9 1.8 0.18 11.4 1.3 1.2 1 0 0 1 1 1 0 C-myb, C-terminal DUF1875 PF08961.5 ETO17737.1 - 0.22 10.7 3.8 0.34 10.2 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) CBS PF00571.23 ETO17739.1 - 3.4e-09 36.3 0.0 5.5e-05 22.8 0.0 2.6 2 1 0 2 2 2 2 CBS domain Voltage_CLC PF00654.15 ETO17740.1 - 2.4e-21 76.1 2.0 2.9e-21 75.8 1.4 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel DUF2628 PF10947.3 ETO17740.1 - 0.18 11.5 1.1 0.41 10.4 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) DUF1700 PF08006.6 ETO17740.1 - 0.86 8.8 6.8 0.073 12.3 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Adaptin_binding PF10199.4 ETO17741.1 - 2.5e-13 50.4 2.0 2.5e-13 50.4 1.4 1.8 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 SID-1_RNA_chan PF13965.1 ETO17741.1 - 0.018 13.2 4.3 0.0092 14.1 1.0 1.8 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 TRAP_alpha PF03896.11 ETO17741.1 - 0.034 13.1 0.8 0.057 12.4 0.3 1.5 1 1 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Mem_trans PF03547.13 ETO17741.1 - 0.11 10.8 0.2 0.15 10.2 0.2 1.3 1 0 0 1 1 1 0 Membrane transport protein Z1 PF10593.4 ETO17741.1 - 0.72 9.0 6.9 0.054 12.6 0.9 1.8 2 0 0 2 2 2 0 Z1 domain C2 PF00168.25 ETO17742.1 - 2.4e-10 40.1 0.9 7.5e-10 38.5 0.6 1.8 1 0 0 1 1 1 1 C2 domain DivIC PF04977.10 ETO17742.1 - 0.00028 20.2 5.9 0.00043 19.7 3.4 1.9 1 1 0 1 1 1 1 Septum formation initiator BCAS2 PF05700.6 ETO17742.1 - 0.012 15.0 4.7 0.022 14.2 3.3 1.4 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) DUF3450 PF11932.3 ETO17742.1 - 0.016 14.4 4.9 0.024 13.9 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) IncA PF04156.9 ETO17742.1 - 0.025 14.1 6.6 0.032 13.8 4.6 1.3 1 0 0 1 1 1 0 IncA protein Myosin_tail_1 PF01576.14 ETO17742.1 - 0.041 11.6 10.4 0.045 11.4 7.2 1.1 1 0 0 1 1 1 0 Myosin tail HALZ PF02183.13 ETO17742.1 - 0.056 13.1 1.6 0.056 13.1 1.1 2.1 2 1 1 3 3 3 0 Homeobox associated leucine zipper Reo_sigmaC PF04582.7 ETO17742.1 - 0.071 12.2 0.4 0.09 11.9 0.2 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Uso1_p115_C PF04871.8 ETO17742.1 - 0.32 10.9 10.9 0.036 13.9 4.6 1.6 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region bZIP_1 PF00170.16 ETO17742.1 - 0.79 9.7 8.7 0.095 12.6 2.8 2.0 2 0 0 2 2 2 0 bZIP transcription factor KLRAQ PF10205.4 ETO17742.1 - 1.6 8.7 11.8 0.099 12.6 3.3 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein DUF972 PF06156.8 ETO17742.1 - 1.8 8.9 9.3 0.39 11.0 3.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) SlyX PF04102.7 ETO17742.1 - 3.7 7.9 9.0 12 6.3 6.1 1.9 1 1 1 2 2 2 0 SlyX C2 PF00168.25 ETO17743.1 - 0.0015 18.3 0.0 0.0056 16.4 0.0 2.0 1 1 1 2 2 2 1 C2 domain Ion_trans PF00520.26 ETO17744.1 - 6.4e-38 130.0 6.4 1.1e-37 129.2 4.4 1.4 1 0 0 1 1 1 1 Ion transport protein Apis_Csd PF11671.3 ETO17744.1 - 0.12 12.2 0.7 0.18 11.5 0.5 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein Peptidase_U4 PF03419.8 ETO17744.1 - 1.6 7.7 8.4 0.23 10.4 0.2 2.1 1 1 1 2 2 2 0 Sporulation factor SpoIIGA Exo_endo_phos PF03372.18 ETO17745.1 - 0.0038 17.1 0.0 0.0057 16.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Auxin_inducible PF02519.9 ETO17745.1 - 0.082 12.9 0.5 0.32 11.0 0.1 2.1 1 1 1 2 2 2 0 Auxin responsive protein PT-HINT PF07591.6 ETO17746.1 - 1.3e-09 38.0 0.2 2.2e-08 34.0 0.1 2.0 1 1 0 1 1 1 1 Pretoxin HINT domain AXH PF08517.7 ETO17746.1 - 2.1e-05 24.6 0.1 3.7e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) YajC PF02699.10 ETO17746.1 - 0.0081 15.8 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Preprotein translocase subunit TNF PF00229.13 ETO17746.1 - 0.06 12.9 0.2 0.11 12.0 0.0 1.5 2 0 0 2 2 2 0 TNF(Tumour Necrosis Factor) family Hint_2 PF13403.1 ETO17746.1 - 0.14 12.0 0.0 0.81 9.6 0.0 1.8 1 1 0 1 1 1 0 Hint domain Cation_ATPase_C PF00689.16 ETO17747.1 - 9.5 5.7 15.2 70 2.8 10.6 2.0 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF3228 PF11539.3 ETO17749.1 - 0.038 13.1 0.2 0.042 12.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3228) PKD_channel PF08016.7 ETO17750.1 - 0.0063 14.9 1.5 0.0074 14.7 0.0 1.7 2 0 0 2 2 2 1 Polycystin cation channel MRVI1 PF05781.7 ETO17750.1 - 0.0069 14.8 0.0 0.0088 14.4 0.0 1.1 1 0 0 1 1 1 1 MRVI1 protein Atrophin-1 PF03154.10 ETO17751.1 - 0.0026 15.9 13.0 0.0026 15.9 9.0 2.0 1 1 1 2 2 2 1 Atrophin-1 family SDA1 PF05285.7 ETO17751.1 - 0.15 11.2 36.3 0.19 10.9 25.2 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 ETO17751.1 - 1.2 7.0 34.6 1.3 6.8 24.0 1.2 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.7 ETO17751.1 - 8.3 4.6 42.6 12 4.1 29.5 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Daxx PF03344.10 ETO17751.1 - 9.5 4.5 38.7 13 4.1 26.8 1.3 1 0 0 1 1 1 0 Daxx Family UPF0172 PF03665.8 ETO17752.1 - 1.4e-05 24.6 5.4 3.7e-05 23.2 3.8 1.7 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0172) Arginase PF00491.16 ETO17753.1 - 7.5e-39 133.6 0.0 9.2e-39 133.3 0.0 1.0 1 0 0 1 1 1 1 Arginase family Aminotran_4 PF01063.14 ETO17754.1 - 1.5e-08 34.4 0.0 2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV ATP-synt_J PF04911.7 ETO17754.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 ATP synthase j chain Aminotran_4 PF01063.14 ETO17755.1 - 3.4e-10 39.8 0.0 3.9e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV ig PF00047.20 ETO17755.1 - 0.13 12.4 0.7 0.68 10.1 0.1 2.3 2 1 0 2 2 2 0 Immunoglobulin domain Pkinase PF00069.20 ETO17756.1 - 4.8e-22 78.3 0.1 1.1e-21 77.1 0.1 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO17756.1 - 2.9e-12 46.1 0.1 3.3e-12 46.0 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO17756.1 - 0.00045 19.3 0.1 0.00057 19.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 ETO17756.1 - 0.0014 18.0 0.0 0.0025 17.1 0.0 1.4 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL GalP_UDP_tr_C PF02744.12 ETO17756.1 - 0.043 13.3 0.0 0.052 13.0 0.0 1.2 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain Anoctamin PF04547.7 ETO17758.1 - 3.1e-10 39.3 2.0 3.1e-10 39.3 1.4 1.8 2 0 0 2 2 2 1 Calcium-activated chloride channel WSN PF02206.13 ETO17759.1 - 0.052 13.3 0.1 0.21 11.3 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function APP_E2 PF12925.2 ETO17759.1 - 0.14 11.6 0.2 5.6 6.4 0.1 2.2 1 1 1 2 2 2 0 E2 domain of amyloid precursor protein Nop14 PF04147.7 ETO17760.1 - 0.021 12.7 19.6 0.27 9.1 6.8 2.3 2 0 0 2 2 2 0 Nop14-like family Nucleoplasmin PF03066.10 ETO17760.1 - 0.16 11.4 25.2 0.13 11.8 5.6 2.6 2 0 0 2 2 2 0 Nucleoplasmin Myc_N PF01056.13 ETO17760.1 - 0.5 9.4 24.8 1 8.4 4.2 3.5 3 0 0 3 3 3 0 Myc amino-terminal region TRAP_alpha PF03896.11 ETO17760.1 - 1.9 7.4 13.2 2 7.3 0.4 2.3 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Pox_Ag35 PF03286.9 ETO17760.1 - 2.9 7.3 22.3 2.2 7.7 2.0 2.8 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Spore_coat_CotO PF14153.1 ETO17760.1 - 3.9 6.8 24.7 5.7 6.3 8.6 2.6 2 0 0 2 2 2 0 Spore coat protein CotO Nop25 PF09805.4 ETO17760.1 - 8.5 6.4 26.6 1.4 9.0 4.1 3.0 3 0 0 3 3 3 0 Nucleolar protein 12 (25kDa) Nucleoplasmin PF03066.10 ETO17761.1 - 0.0099 15.3 10.5 0.2 11.1 0.5 2.5 2 0 0 2 2 2 2 Nucleoplasmin DUF605 PF04652.11 ETO17761.1 - 2.5 7.4 32.1 3.3 6.9 22.2 1.1 1 0 0 1 1 1 0 Vta1 like PalH PF08733.5 ETO17762.1 - 0.00045 19.1 4.2 0.00052 18.9 2.9 1.0 1 0 0 1 1 1 1 PalH/RIM21 DUF912 PF06024.7 ETO17763.1 - 0.0012 18.8 5.8 0.0012 18.8 4.0 3.5 3 1 1 4 4 4 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Tetraspannin PF00335.15 ETO17763.1 - 0.014 14.6 9.6 0.085 12.1 6.7 2.0 1 1 0 1 1 1 0 Tetraspanin family DUF2039 PF10217.4 ETO17763.1 - 0.051 13.6 1.1 0.051 13.6 0.8 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2039) TFIIF_alpha PF05793.7 ETO17763.1 - 0.086 11.1 22.5 0.11 10.8 15.6 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Utp14 PF04615.8 ETO17763.1 - 1.1 7.3 27.4 1.5 6.8 19.0 1.1 1 0 0 1 1 1 0 Utp14 protein PBP1_TM PF14812.1 ETO17763.1 - 1.2 9.4 0.0 1.2 9.4 0.0 3.5 3 1 1 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Kinesin PF00225.18 ETO17765.1 - 7.3e-31 107.1 15.0 3.4e-17 62.1 0.0 4.7 3 2 1 4 4 4 2 Kinesin motor domain AAA PF00004.24 ETO17766.1 - 6.9e-21 74.8 0.0 1.2e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 ETO17766.1 - 0.041 13.7 0.0 0.096 12.5 0.0 1.6 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain Tricho_coat PF05892.6 ETO17768.1 - 0.14 11.4 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 Trichovirus coat protein FoP_duplication PF13865.1 ETO17769.1 - 0.0045 17.3 0.2 0.0096 16.3 0.1 1.5 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 Ribonuc_red_lgC PF02867.10 ETO17769.1 - 0.02 13.4 0.5 0.024 13.1 0.4 1.1 1 0 0 1 1 1 0 Ribonucleotide reductase, barrel domain Ndc1_Nup PF09531.5 ETO17769.1 - 0.042 12.2 0.3 0.046 12.1 0.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Methyltransf_12 PF08242.7 ETO17771.1 - 4.4e-10 39.9 0.0 8.7e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO17771.1 - 9.4e-09 35.8 0.0 2.8e-08 34.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETO17771.1 - 1.7e-08 34.8 0.0 2.8e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO17771.1 - 1.7e-07 30.9 0.0 3.3e-07 29.9 0.0 1.4 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETO17771.1 - 5.1e-06 26.7 0.0 7.9e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETO17771.1 - 6.4e-06 25.9 0.0 7.9e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 ETO17771.1 - 4.4e-05 22.6 0.0 6.1e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.12 ETO17771.1 - 5.2e-05 22.3 0.1 0.00024 20.2 0.1 1.9 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 ETO17771.1 - 5.7e-05 23.1 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 ETO17771.1 - 0.0093 15.2 0.0 0.018 14.3 0.0 1.6 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase MTS PF05175.9 ETO17771.1 - 0.011 15.1 0.0 0.039 13.3 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase small domain Methyltransf_21 PF05050.7 ETO17771.1 - 0.014 15.2 0.1 0.026 14.4 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase FkbM domain FtsJ PF01728.14 ETO17771.1 - 0.026 14.4 0.0 0.076 12.9 0.0 1.8 1 1 0 1 1 1 0 FtsJ-like methyltransferase Ion_trans PF00520.26 ETO17772.1 - 0.0043 16.3 8.7 0.0043 16.3 6.0 1.5 2 0 0 2 2 2 1 Ion transport protein TraL PF07178.6 ETO17772.1 - 0.081 12.9 1.7 4.5 7.3 0.1 2.5 2 0 0 2 2 2 0 TraL protein EI24 PF07264.6 ETO17772.1 - 2 7.8 9.6 0.12 11.7 1.7 2.2 3 0 0 3 3 3 0 Etoposide-induced protein 2.4 (EI24) Ion_trans PF00520.26 ETO17773.1 - 3.7e-14 52.4 18.6 2e-11 43.4 8.6 2.7 2 1 0 2 2 2 2 Ion transport protein PRP1_N PF06424.7 ETO17773.1 - 1.9 8.7 8.6 1.1 9.6 2.9 2.3 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Ion_trans PF00520.26 ETO17774.1 - 7.6e-14 51.4 14.6 7.6e-14 51.4 10.1 1.6 2 0 0 2 2 2 1 Ion transport protein Na_trans_assoc PF06512.8 ETO17774.1 - 0.014 15.3 0.9 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 Sodium ion transport-associated Hid1 PF12722.2 ETO17775.1 - 1.9 6.0 17.2 2.6 5.6 11.9 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Radial_spoke PF04712.7 ETO17776.1 - 0.0089 14.8 1.7 0.11 11.2 0.2 2.0 2 0 0 2 2 2 1 Radial spokehead-like protein Mic1 PF07035.7 ETO17776.1 - 0.019 14.3 0.0 0.14 11.5 0.0 2.0 2 0 0 2 2 2 0 Colon cancer-associated protein Mic1-like VIT1 PF01988.14 ETO17776.1 - 0.31 10.5 1.6 0.43 10.0 1.1 1.2 1 1 0 1 1 1 0 VIT family BSP_II PF05432.6 ETO17776.1 - 0.84 8.8 7.3 0.21 10.8 1.7 2.0 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) TPX2 PF06886.6 ETO17776.1 - 1.7 8.7 8.1 0.17 11.9 2.3 1.7 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) DnaI_N PF07319.6 ETO17777.1 - 0.18 12.1 8.1 0.24 11.6 5.6 1.2 1 0 0 1 1 1 0 Primosomal protein DnaI N-terminus Drf_GBD PF06371.8 ETO17777.1 - 0.34 10.2 5.3 0.38 10.0 3.7 1.2 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain Borrelia_P83 PF05262.6 ETO17777.1 - 3.3 5.8 12.6 3.5 5.8 8.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4193 PF13834.1 ETO17777.1 - 6.7 6.9 7.9 4.2 7.5 3.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4193) Tropomyosin PF00261.15 ETO17779.1 - 0.00045 19.3 23.1 0.00057 19.0 16.0 1.1 1 0 0 1 1 1 1 Tropomyosin PEPcase_2 PF14010.1 ETO17779.1 - 0.0013 17.1 5.2 0.0018 16.6 3.6 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase GAS PF13851.1 ETO17779.1 - 0.0023 17.1 9.7 0.0023 17.1 6.7 2.2 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding HALZ PF02183.13 ETO17779.1 - 0.0037 16.9 12.7 0.055 13.2 0.7 3.4 3 0 0 3 3 3 2 Homeobox associated leucine zipper DUF730 PF05325.6 ETO17779.1 - 0.0044 16.8 3.7 0.0075 16.0 1.3 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF730) DivIVA PF05103.8 ETO17779.1 - 0.22 11.5 22.5 0.059 13.4 7.9 2.2 1 1 1 2 2 2 0 DivIVA protein CENP-F_leu_zip PF10473.4 ETO17779.1 - 0.69 9.7 27.0 5.3 6.8 6.7 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.4 ETO17779.1 - 0.7 8.7 16.2 1 8.2 11.3 1.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HalX PF08663.5 ETO17779.1 - 1.1 9.2 8.8 0.15 12.0 1.7 2.6 2 1 0 2 2 2 0 HalX domain TipAS PF07739.8 ETO17779.1 - 1.2 9.4 7.9 1.4 9.2 0.4 2.3 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain Coiled-coil_56 PF09813.4 ETO17779.1 - 2 8.4 5.7 0.7 9.9 1.6 2.0 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 56 Herpes_BLRF2 PF05812.7 ETO17779.1 - 2.3 8.0 14.8 1.1 9.0 7.0 2.2 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein DUF2870 PF11069.3 ETO17779.1 - 3.5 7.7 10.8 7.6 6.6 1.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2870) Rab5-bind PF09311.6 ETO17779.1 - 4.4 7.1 27.4 5.8e+02 0.2 19.0 2.9 1 1 0 1 1 1 0 Rabaptin-like protein DUF3708 PF12501.3 ETO17779.1 - 5.1 6.8 6.4 3.3 7.5 3.0 1.7 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter NPV_P10 PF05531.7 ETO17779.1 - 5.9 7.2 9.4 1.1 9.5 0.5 2.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein RGS PF00615.14 ETO17781.1 - 0.002 18.1 0.5 2 8.5 0.0 2.7 2 1 0 2 2 2 2 Regulator of G protein signaling domain Lactamase_B PF00753.22 ETO17782.1 - 1.4e-11 44.4 0.0 4.1e-11 42.8 0.0 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETO17782.1 - 6.2e-10 38.9 0.0 8.9e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PDEase_II PF02112.10 ETO17782.1 - 0.014 14.2 0.1 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Lactamase_B_3 PF13483.1 ETO17782.1 - 0.06 13.0 0.0 0.15 11.7 0.0 1.8 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Beta-Casp PF10996.3 ETO17782.1 - 0.06 13.2 0.9 0.31 10.9 0.1 2.4 3 0 0 3 3 3 0 Beta-Casp domain NAD_binding_10 PF13460.1 ETO17783.1 - 2.4e-14 53.7 0.0 4.1e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 ETO17783.1 - 4.5e-05 22.6 0.0 6.1e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 ETO17783.1 - 6.2e-05 22.0 0.0 0.00014 20.8 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.8 ETO17783.1 - 0.00029 20.1 0.0 0.0005 19.3 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 ETO17783.1 - 0.00036 19.3 0.0 0.00054 18.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 ETO17783.1 - 0.0032 17.3 0.0 0.0053 16.6 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 ETO17783.1 - 0.042 14.1 0.0 0.077 13.3 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 ETO17783.1 - 0.047 13.8 0.0 0.072 13.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Caps_synth PF05704.7 ETO17783.1 - 0.052 12.7 0.1 0.076 12.1 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Epimerase PF01370.16 ETO17783.1 - 0.053 12.9 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.20 ETO17783.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase NUFIP1 PF10453.4 ETO17784.1 - 1.1e-06 28.0 3.6 1.1e-06 28.0 2.5 2.3 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Peptidase_S28 PF05577.7 ETO17784.1 - 0.022 13.3 1.6 0.04 12.5 1.1 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Utp14 PF04615.8 ETO17785.1 - 0.81 7.7 33.6 0.93 7.5 23.3 1.0 1 0 0 1 1 1 0 Utp14 protein SOBP PF15279.1 ETO17785.1 - 1.9 8.7 16.4 2.4 8.4 11.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein BTV_NS2 PF04514.7 ETO17785.1 - 3.6 6.3 15.3 4.2 6.1 10.6 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Nop53 PF07767.6 ETO17786.1 - 0.18 10.7 22.2 0.22 10.4 15.4 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Med15 PF09606.5 ETO17786.1 - 0.22 9.7 19.5 0.22 9.6 13.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Peptidase_U57 PF05582.7 ETO17786.1 - 0.36 9.7 5.5 0.38 9.6 3.8 1.3 1 0 0 1 1 1 0 YabG peptidase U57 Radical_SAM_N PF08497.5 ETO17786.1 - 0.69 8.7 4.9 0.84 8.5 3.4 1.1 1 0 0 1 1 1 0 Radical SAM N-terminal DUF2968 PF11180.3 ETO17786.1 - 0.71 9.2 19.6 1 8.6 13.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Suf PF05843.9 ETO17786.1 - 0.75 9.4 10.9 0.82 9.3 7.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FecR PF04773.8 ETO17786.1 - 0.79 9.9 4.0 1.9 8.7 2.7 1.7 1 1 1 2 2 2 0 FecR protein Raftlin PF15250.1 ETO17786.1 - 1 7.8 13.3 1.1 7.6 9.3 1.1 1 0 0 1 1 1 0 Raftlin AUX_IAA PF02309.11 ETO17786.1 - 1.4 8.6 12.7 1.9 8.2 8.8 1.2 1 0 0 1 1 1 0 AUX/IAA family SprA-related PF12118.3 ETO17786.1 - 1.5 8.0 30.3 1.8 7.8 21.0 1.1 1 0 0 1 1 1 0 SprA-related family Peptidase_S64 PF08192.6 ETO17786.1 - 1.7 6.8 14.7 1.8 6.7 10.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 Membralin PF09746.4 ETO17786.1 - 2.5 7.0 6.7 2.7 6.9 4.6 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF4407 PF14362.1 ETO17786.1 - 4.7 6.0 8.4 5.7 5.7 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6 PF04111.7 ETO17786.1 - 5 6.0 22.2 6.2 5.7 15.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Gastrin PF00918.12 ETO17786.1 - 6.1 7.6 12.5 1.7 9.4 6.7 1.5 2 0 0 2 2 1 0 Gastrin/cholecystokinin family Atg14 PF10186.4 ETO17786.1 - 7.8 5.3 18.1 8.9 5.1 12.6 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_2 PF07724.9 ETO17787.1 - 9e-29 100.5 0.3 1.1e-28 100.2 0.2 1.1 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 ETO17787.1 - 2.1e-08 34.4 0.1 2.4e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF1342 PF07072.6 ETO17788.1 - 0.013 15.2 1.8 0.024 14.3 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1342) OmpH PF03938.9 ETO17788.1 - 0.13 12.1 5.0 0.14 12.1 0.6 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF3742 PF12553.3 ETO17788.1 - 0.85 10.1 9.7 0.5 10.8 5.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3742) DUF2457 PF10446.4 ETO17788.1 - 0.98 8.0 11.2 1.6 7.3 7.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.7 ETO17788.1 - 1.3 8.2 13.8 1.7 7.8 9.1 1.5 1 1 0 1 1 1 0 SDA1 Mei5 PF10376.4 ETO17788.1 - 4.2 6.8 9.0 0.32 10.5 2.1 2.0 2 0 0 2 2 2 0 Double-strand recombination repair protein IncA PF04156.9 ETO17789.1 - 0.0087 15.6 16.5 0.0087 15.6 11.4 3.6 3 1 0 3 3 3 2 IncA protein AAA_13 PF13166.1 ETO17789.1 - 0.036 12.5 33.9 0.0026 16.2 18.9 2.0 2 0 0 2 2 2 0 AAA domain Luteo_PO PF04662.8 ETO17789.1 - 0.13 11.6 1.5 8.7 5.7 0.1 2.5 2 0 0 2 2 2 0 Luteovirus P0 protein Lipoprotein_6 PF01441.14 ETO17789.1 - 1 9.1 26.7 0.014 15.2 12.1 2.5 3 0 0 3 3 3 0 Lipoprotein AIP3 PF03915.8 ETO17789.1 - 1.3 7.8 35.3 0.3 9.9 6.8 3.2 1 1 2 3 3 3 0 Actin interacting protein 3 U5_2-snRNA_bdg PF10597.4 ETO17789.1 - 2.1 7.9 7.1 0.63 9.6 1.3 2.6 3 0 0 3 3 3 0 U5-snRNA binding site 2 of PrP8 Z1 PF10593.4 ETO17789.1 - 3.8 6.6 20.8 0.51 9.4 8.1 2.5 1 1 1 2 2 2 0 Z1 domain Reo_sigmaC PF04582.7 ETO17789.1 - 9.1 5.3 8.7 1 8.4 1.5 2.4 3 0 0 3 3 3 0 Reovirus sigma C capsid protein Hat1_N PF10394.4 ETO17789.1 - 9.9 6.1 17.0 19 5.3 0.1 3.3 1 1 1 2 2 2 0 Histone acetyl transferase HAT1 N-terminus Sad1_UNC PF07738.8 ETO17790.1 - 1.2e-05 25.0 1.6 0.00091 19.0 1.1 3.1 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF4463 PF14703.1 ETO17791.1 - 0.17 12.3 1.5 20 5.8 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) SlyX PF04102.7 ETO17791.1 - 0.36 11.2 8.3 0.15 12.4 0.9 2.7 2 1 1 3 3 3 0 SlyX GP41 PF00517.12 ETO17791.1 - 1 8.8 7.3 1.2 8.6 0.4 2.3 2 0 0 2 2 2 0 Retroviral envelope protein NPV_P10 PF05531.7 ETO17791.1 - 2.6 8.3 7.3 7.4 6.8 4.2 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Sox_N PF12444.3 ETO17791.1 - 5.2 8.2 7.2 41 5.3 5.0 2.4 1 1 0 1 1 1 0 Sox developmental protein N terminal Spectrin PF00435.16 ETO17791.1 - 5.7 7.2 9.3 27 5.1 0.3 2.3 1 1 1 2 2 2 0 Spectrin repeat DUF2654 PF10849.3 ETO17792.1 - 0.014 15.1 0.3 0.36 10.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2654) Rhamnogal_lyase PF06045.6 ETO17792.1 - 0.029 13.6 0.6 0.037 13.3 0.4 1.2 1 0 0 1 1 1 0 Rhamnogalacturonate lyase family DUF3816 PF12822.2 ETO17793.1 - 0.032 14.1 0.9 0.036 13.9 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) DUF4500 PF14937.1 ETO17793.1 - 0.15 11.9 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) WBP-1 PF11669.3 ETO17793.1 - 2.2 8.3 7.0 0.53 10.3 2.4 1.8 1 1 1 2 2 2 0 WW domain-binding protein 1 Daxx PF03344.10 ETO17794.1 - 0.5 8.7 20.9 0.67 8.3 14.5 1.0 1 0 0 1 1 1 0 Daxx Family Pkinase PF00069.20 ETO17795.1 - 7.1e-41 140.0 0.1 8e-41 139.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO17795.1 - 2.2e-19 69.5 0.0 2.4e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO17795.1 - 0.00052 19.0 0.0 0.00071 18.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETO17795.1 - 0.0014 17.7 0.1 0.0022 17.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 ETO17795.1 - 0.015 14.6 0.1 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 ETO17795.1 - 0.019 14.7 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 ETO17795.1 - 0.051 12.9 0.0 0.23 10.7 0.0 2.0 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DUF3738 PF12543.3 ETO17795.1 - 0.18 11.3 0.4 0.28 10.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3738) GP41 PF00517.12 ETO17796.1 - 1.6 8.2 5.4 0.25 10.8 0.3 2.1 1 1 1 2 2 2 0 Retroviral envelope protein Cytochrom_B561 PF03188.11 ETO17798.1 - 7.9e-08 32.2 3.4 7.9e-08 32.2 2.3 1.7 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DOMON PF03351.12 ETO17798.1 - 6.8e-06 26.0 0.1 1.2e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 DOMON domain YwiC PF14256.1 ETO17798.1 - 0.00028 20.9 0.3 0.00028 20.9 0.2 1.7 1 1 1 2 2 2 1 YwiC-like protein SdpI PF13630.1 ETO17798.1 - 0.0051 16.4 13.6 0.065 12.9 2.5 2.6 2 0 0 2 2 2 2 SdpI/YhfL protein family DUF3784 PF12650.2 ETO17798.1 - 1.1 9.1 11.1 4.5 7.2 1.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) PI3Ka PF00613.15 ETO17799.1 - 2.8e-45 153.7 2.1 5.8e-45 152.7 1.4 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 ETO17799.1 - 5.8e-36 124.1 0.1 1.5e-35 122.8 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 ETO17799.1 - 3e-16 59.4 0.0 6.5e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.13 ETO17799.1 - 6.6e-13 48.5 0.0 2.6e-12 46.5 0.0 2.0 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain GPCR_chapero_1 PF11904.3 ETO17799.1 - 0.011 14.8 5.4 0.15 11.1 0.0 2.9 3 1 0 3 3 3 0 GPCR-chaperone Glyco_hydro_31 PF01055.21 ETO17801.1 - 5.1e-18 65.1 0.0 5.6e-18 64.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4203 PF13886.1 ETO17802.1 - 2.4e-18 66.3 10.8 3.1e-18 66.0 7.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF4063 PF13272.1 ETO17802.1 - 0.086 12.6 1.1 0.19 11.5 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4063) ABC2_membrane_4 PF12730.2 ETO17802.1 - 0.63 9.1 14.5 1 8.4 10.0 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein NARP1 PF12569.3 ETO17803.1 - 0.032 13.0 4.0 0.041 12.6 2.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 U79_P34 PF03064.11 ETO17803.1 - 0.11 12.0 4.4 0.14 11.6 3.1 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 fn3 PF00041.16 ETO17804.1 - 0.0044 17.1 1.4 0.058 13.5 0.0 2.9 3 1 0 3 3 3 1 Fibronectin type III domain UCN2 PF11613.3 ETO17804.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Agonist of corticotropin releasing factor R2, Urocortin-2 WD40 PF00400.27 ETO17806.1 - 3.5e-66 216.8 20.0 2.9e-12 45.9 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO17806.1 - 7.5e-07 27.6 1.5 0.13 10.3 0.0 3.3 2 1 1 3 3 3 3 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO17806.1 - 5.5e-06 26.2 1.0 0.6 10.0 0.0 5.3 3 2 3 6 6 6 1 Domain of unknown function (DUF3601) Cytochrom_D1 PF02239.11 ETO17806.1 - 3.5e-05 22.2 0.3 0.035 12.3 0.0 2.5 2 1 0 2 2 2 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO17806.1 - 6.1e-05 22.5 0.1 0.00034 20.1 0.0 2.3 1 1 0 1 1 1 1 PQQ-like domain DPPIV_N PF00930.16 ETO17806.1 - 0.0001 21.0 0.0 0.039 12.5 0.0 3.6 2 2 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.7 ETO17806.1 - 0.0019 17.8 5.8 32 4.3 0.0 6.0 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO17806.1 - 0.0026 17.9 2.4 2.7 8.3 0.0 4.1 2 1 2 4 4 4 1 Resistin Proteasome_A_N PF10584.4 ETO17806.1 - 1.3 8.3 7.5 27 4.2 0.1 4.3 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature AGTRAP PF06396.6 ETO17807.1 - 0.19 11.4 3.0 0.25 11.0 2.1 1.1 1 0 0 1 1 1 0 Angiotensin II, type I receptor-associated protein (AGTRAP) Collagen PF01391.13 ETO17808.1 - 5.9e-06 25.7 1.7 1e-05 24.9 1.2 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Conotoxin PF02950.12 ETO17808.1 - 3.1 8.6 0.0 3.1 8.6 0.0 4.1 3 1 0 3 3 3 0 Conotoxin Trypan_PARP PF05887.6 ETO17808.1 - 8.6 6.1 47.2 2.9 7.7 7.7 2.9 2 1 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) LUC7 PF03194.10 ETO17810.1 - 2.2e-17 63.4 1.4 2.6e-17 63.2 1.0 1.0 1 0 0 1 1 1 1 LUC7 N_terminus BLOC1_2 PF10046.4 ETO17810.1 - 0.016 15.3 1.5 0.041 14.0 1.1 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Seryl_tRNA_N PF02403.17 ETO17810.1 - 0.019 14.9 1.9 0.037 14.0 1.3 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain zf-C2H2_2 PF12756.2 ETO17810.1 - 0.019 15.0 0.1 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) MORN_2 PF07661.8 ETO17810.1 - 0.063 13.3 0.7 0.17 11.9 0.5 1.8 1 0 0 1 1 1 0 MORN repeat variant Rapamycin_bind PF08771.6 ETO17810.1 - 0.092 12.8 0.2 0.13 12.3 0.1 1.4 1 1 0 1 1 1 0 Rapamycin binding domain zf-DHHC PF01529.15 ETO17812.1 - 1.1e-29 103.0 6.3 1.1e-29 103.0 4.3 2.2 1 1 1 2 2 2 1 DHHC palmitoyltransferase ADH_N PF08240.7 ETO17812.1 - 3.9 7.2 8.1 1.8 8.3 3.6 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain DUF2975 PF11188.3 ETO17812.1 - 5.2 6.7 6.9 0.84 9.3 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Aldo_ket_red PF00248.16 ETO17813.1 - 2e-08 33.3 0.1 2.8e-08 32.9 0.1 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Intron_maturas2 PF01348.16 ETO17813.1 - 0.0095 15.9 0.4 0.017 15.0 0.3 1.5 1 0 0 1 1 1 1 Type II intron maturase Wzz PF02706.10 ETO17813.1 - 0.062 13.1 0.2 0.067 13.0 0.1 1.2 1 0 0 1 1 1 0 Chain length determinant protein EST1 PF10374.4 ETO17813.1 - 1.1 9.2 5.7 0.79 9.7 0.7 2.2 2 1 0 2 2 2 0 Telomerase activating protein Est1 DUF592 PF04574.8 ETO17814.1 - 1.1 8.8 5.1 0.26 10.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF592) Pox_E10 PF04805.7 ETO17815.1 - 0.12 11.9 0.3 0.23 11.0 0.2 1.5 1 0 0 1 1 1 0 E10-like protein conserved region DUF3408 PF11888.3 ETO17819.1 - 1.5 8.7 10.0 4.9 7.0 3.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) MSA_2 PF00985.12 ETO17820.1 - 0.028 14.5 2.2 0.038 14.1 1.5 1.2 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family NLE PF08154.7 ETO17820.1 - 0.041 13.8 0.2 0.083 12.9 0.1 1.4 1 0 0 1 1 1 0 NLE (NUC135) domain eIF3_p135 PF12807.2 ETO17820.1 - 0.56 10.1 2.5 0.78 9.6 1.7 1.3 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 Rota_VP2 PF05087.7 ETO17820.1 - 2 6.2 5.7 2.4 5.9 4.0 1.0 1 0 0 1 1 1 0 Rotavirus VP2 protein DUF547 PF04784.9 ETO17822.1 - 2.7e-06 27.2 0.0 5.9e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 DUF938 PF06080.7 ETO17823.1 - 1.7e-36 125.7 0.0 6.2e-36 123.8 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_18 PF12847.2 ETO17823.1 - 0.0037 17.8 0.0 0.0073 16.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETO17823.1 - 0.042 13.5 0.0 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain AMP-binding PF00501.23 ETO17824.1 - 5.4e-16 57.9 0.6 7.9e-16 57.4 0.4 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETO17824.1 - 2.4e-07 31.5 0.0 3.3e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HSP70 PF00012.15 ETO17825.1 - 1.3e-09 36.5 10.3 5.7e-05 21.2 0.5 3.3 2 1 1 3 3 3 2 Hsp70 protein DSBA PF01323.15 ETO17826.1 - 6.5e-10 38.8 0.0 7.1e-10 38.7 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.1 ETO17826.1 - 0.00031 20.5 0.0 0.00088 19.0 0.0 1.8 1 1 1 2 2 2 1 Thioredoxin domain Thioredoxin_4 PF13462.1 ETO17826.1 - 0.00039 20.4 0.0 0.00047 20.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DisA-linker PF10635.4 ETO17826.1 - 0.045 13.2 0.1 0.057 12.9 0.1 1.1 1 0 0 1 1 1 0 DisA bacterial checkpoint controller linker region Carboxyl_trans PF01039.17 ETO17827.1 - 1.6e-69 234.6 0.0 1.1e-34 119.6 0.0 2.1 2 0 0 2 2 2 2 Carboxyl transferase domain Orthopox_F7 PF05813.7 ETO17827.1 - 0.035 13.9 0.7 3 7.8 0.2 2.9 2 0 0 2 2 2 0 Orthopoxvirus F7 protein Imm42 PF15601.1 ETO17828.1 - 0.0047 16.3 2.8 0.0047 16.3 2.0 1.6 1 1 0 1 1 1 1 Immunity protein 42 TMEM247 PF15444.1 ETO17828.1 - 0.0055 16.5 1.3 0.0063 16.3 0.9 1.1 1 0 0 1 1 1 1 Transmembrane protein 247 Mnd1 PF03962.10 ETO17828.1 - 0.0098 15.5 7.6 0.0098 15.5 5.2 1.5 1 1 0 1 1 1 1 Mnd1 family DUF87 PF01935.12 ETO17828.1 - 0.01 15.6 1.0 0.011 15.5 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF1640 PF07798.6 ETO17828.1 - 0.042 13.8 2.8 1.3 9.0 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) DUF4359 PF14271.1 ETO17828.1 - 0.12 12.7 3.5 4.1 7.8 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4359) TIR_2 PF13676.1 ETO17828.1 - 0.22 11.6 1.2 0.44 10.7 0.4 1.8 1 1 0 1 1 1 0 TIR domain Iron_permease PF04120.7 ETO17828.1 - 0.32 10.5 4.1 0.57 9.7 2.8 1.4 1 0 0 1 1 1 0 Low affinity iron permease Lig_chan PF00060.21 ETO17828.1 - 0.37 10.4 2.0 0.38 10.4 0.6 1.6 1 1 1 2 2 2 0 Ligand-gated ion channel DUF842 PF05811.8 ETO17828.1 - 0.51 9.8 6.2 1.4 8.3 4.3 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) LUC7 PF03194.10 ETO17828.1 - 1 8.8 7.4 1.2 8.5 5.1 1.3 1 0 0 1 1 1 0 LUC7 N_terminus Bap31 PF05529.7 ETO17828.1 - 2.2 7.7 8.8 2.4 7.5 4.2 2.0 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like PhoU PF01895.14 ETO17828.1 - 2.6 8.5 6.5 21 5.6 4.5 2.1 1 1 0 1 1 1 0 PhoU domain HR1 PF02185.11 ETO17828.1 - 2.6 7.8 12.4 1.6 8.5 3.1 3.3 2 2 0 2 2 2 0 Hr1 repeat TMF_DNA_bd PF12329.3 ETO17828.1 - 4.3 7.2 20.7 2.1 8.2 2.3 3.4 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF641 PF04859.7 ETO17828.1 - 5.6 6.7 7.1 1.1 8.9 1.8 1.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Abhydrolase_2 PF02230.11 ETO17830.1 - 0.11 11.8 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF723 PF05265.8 ETO17831.1 - 0.045 13.5 0.1 8.7 6.2 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF723) DUF1777 PF08648.7 ETO17831.1 - 0.075 12.7 3.0 0.1 12.3 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) BAF1_ABF1 PF04684.8 ETO17831.1 - 0.51 9.1 7.1 0.52 9.1 4.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Guanylate_kin PF00625.16 ETO17831.1 - 0.81 9.1 4.7 1.2 8.6 3.3 1.2 1 0 0 1 1 1 0 Guanylate kinase DUF4175 PF13779.1 ETO17831.1 - 1.2 6.7 9.9 1.3 6.6 6.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4045 PF13254.1 ETO17831.1 - 3.6 6.7 7.1 5.4 6.1 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4045) DUF3484 PF11983.3 ETO17832.1 - 0.0015 19.2 3.1 0.0025 18.5 2.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3484) DUF3785 PF12653.2 ETO17832.1 - 0.044 13.6 0.5 0.044 13.6 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3785) AgrB PF04647.10 ETO17832.1 - 0.065 12.2 1.9 1.6 7.7 0.1 2.2 2 0 0 2 2 2 0 Accessory gene regulator B PDR_CDR PF06422.7 ETO17832.1 - 0.33 10.6 2.6 0.28 10.8 0.3 1.8 2 0 0 2 2 2 0 CDR ABC transporter YMF19 PF02326.10 ETO17832.1 - 0.65 10.6 11.8 8.4 7.0 0.0 2.5 2 1 0 2 2 2 0 Plant ATP synthase F0 DUF87 PF01935.12 ETO17833.1 - 0.25 11.1 2.9 0.3 10.8 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF87 CCDC32 PF14989.1 ETO17833.1 - 0.35 10.6 4.9 1.1 9.0 3.4 1.8 1 1 0 1 1 1 0 Coiled-coil domain containing 32 DUF3373 PF11853.3 ETO17833.1 - 1.3 7.4 5.1 2.9 6.3 3.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3373) Glyco_transf_4 PF13439.1 ETO17834.1 - 1.1e-07 31.7 0.0 2.9e-05 23.8 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 ETO17834.1 - 6.5e-06 26.3 0.0 8.9e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 ETO17834.1 - 0.0016 18.2 0.4 0.047 13.5 0.3 2.1 1 1 0 1 1 1 1 Glycosyl transferase 4-like YjeF_N PF03853.10 ETO17835.1 - 1.1e-14 54.3 0.0 1.3e-14 54.2 0.0 1.0 1 0 0 1 1 1 1 YjeF-related protein N-terminus Yippee-Mis18 PF03226.9 ETO17836.1 - 0.0046 16.9 1.0 0.065 13.2 0.4 2.3 1 1 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF3379 PF11859.3 ETO17836.1 - 0.021 13.9 0.3 0.033 13.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) RuvA_C PF07499.8 ETO17836.1 - 0.098 12.8 1.7 0.2 11.8 1.1 1.6 1 0 0 1 1 1 0 RuvA, C-terminal domain DUF4110 PF13422.1 ETO17836.1 - 0.24 11.2 3.5 0.28 11.0 1.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4110) Ribosomal_L22 PF00237.14 ETO17836.1 - 0.74 9.7 4.3 0.41 10.6 1.3 1.8 2 0 0 2 2 2 0 Ribosomal protein L22p/L17e G-alpha PF00503.15 ETO17837.1 - 1.8e-17 63.1 2.1 2.4e-17 62.7 1.4 1.1 1 0 0 1 1 1 1 G-protein alpha subunit ubiquitin PF00240.18 ETO17838.1 - 2.3e-17 62.1 0.0 8.3e-17 60.3 0.0 2.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 ETO17838.1 - 2e-08 33.7 0.0 5.8e-08 32.3 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PT-HINT PF07591.6 ETO17838.1 - 2.5e-06 27.4 0.1 2.5e-06 27.4 0.1 2.3 3 0 0 3 3 3 1 Pretoxin HINT domain Hint PF01079.15 ETO17838.1 - 2.4e-05 23.6 0.0 4.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Hint module AXH PF08517.7 ETO17838.1 - 0.0071 16.5 0.0 0.041 14.0 0.0 2.2 2 0 0 2 2 2 1 Ataxin-1 and HBP1 module (AXH) Oxidored_q1_C PF01010.14 ETO17838.1 - 0.047 13.1 1.9 0.12 11.8 1.3 1.6 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus UN_NPL4 PF11543.3 ETO17838.1 - 0.05 13.8 0.1 0.41 10.9 0.0 2.6 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 LdpA_C PF12617.3 ETO17841.1 - 0.1 11.8 0.1 0.22 10.7 0.0 1.6 2 0 0 2 2 2 0 Iron-Sulfur binding protein C terminal IFT46_B_C PF12317.3 ETO17841.1 - 0.94 8.8 5.9 8.3 5.7 1.1 2.4 1 1 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal TFIIA PF03153.8 ETO17842.1 - 0.097 12.5 20.6 0.17 11.7 14.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FLO_LFY PF01698.11 ETO17842.1 - 0.11 11.3 8.1 0.18 10.6 5.6 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Cwf_Cwc_15 PF04889.7 ETO17842.1 - 0.13 11.9 21.6 0.017 14.8 12.1 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Prothymosin PF03247.9 ETO17842.1 - 1.1 9.4 23.1 0.13 12.4 11.9 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family Nucleo_P87 PF07267.6 ETO17842.1 - 1.2 7.6 12.2 1.8 7.1 8.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Nucleoplasmin PF03066.10 ETO17842.1 - 5.8 6.4 24.5 1.6 8.2 14.6 1.6 1 1 0 1 1 1 0 Nucleoplasmin HEAT_2 PF13646.1 ETO17843.1 - 2.4e-19 69.3 0.1 9.5e-05 22.6 0.0 6.5 2 2 3 6 6 6 3 HEAT repeats NACHT PF05729.7 ETO17843.1 - 7.2e-12 45.2 0.1 3.6e-11 43.0 0.0 2.3 2 0 0 2 2 2 1 NACHT domain HEAT PF02985.17 ETO17843.1 - 3e-11 42.3 4.5 0.017 15.1 0.0 7.5 7 0 0 7 7 7 2 HEAT repeat Ank_2 PF12796.2 ETO17843.1 - 7.8e-09 35.7 0.2 7.1e-08 32.6 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO17843.1 - 5.1e-08 32.9 0.3 3.2e-07 30.3 0.1 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) HEAT_EZ PF13513.1 ETO17843.1 - 5.8e-08 32.9 1.4 0.0019 18.6 0.0 5.9 5 2 3 8 8 8 1 HEAT-like repeat Ank_3 PF13606.1 ETO17843.1 - 1.4e-07 31.0 0.1 3.9e-05 23.4 0.0 3.3 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.25 ETO17843.1 - 2.2e-07 30.3 0.1 3.9e-06 26.3 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 ETO17843.1 - 7.7e-07 29.4 0.2 3.7e-06 27.3 0.2 2.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) SpoU_methylas_C PF12105.3 ETO17843.1 - 0.0022 17.4 0.1 0.0072 15.8 0.1 1.9 1 0 0 1 1 1 1 SpoU, rRNA methylase, C-terminal DUF1843 PF08898.5 ETO17843.1 - 0.14 12.2 0.2 0.5 10.4 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) Actin PF00022.14 ETO17844.1 - 3.6e-110 368.0 0.0 1.3e-109 366.2 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 ETO17844.1 - 0.0036 15.9 0.0 0.25 9.9 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein RE_Eco29kI PF09517.5 ETO17844.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Eco29kI restriction endonuclease WD40 PF00400.27 ETO17845.1 - 1.6e-10 40.4 1.9 1.4e-05 24.7 0.0 3.4 3 1 0 3 3 3 2 WD domain, G-beta repeat Peptidase_M16_C PF05193.16 ETO17846.1 - 0.00033 20.3 1.2 0.0025 17.5 0.0 2.3 2 1 0 2 2 2 1 Peptidase M16 inactive domain Gag_p17 PF00540.13 ETO17846.1 - 0.073 12.8 0.1 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 gag gene protein p17 (matrix protein) DUF2036 PF09724.4 ETO17847.1 - 2.3e-47 161.7 6.0 5.3e-47 160.5 4.1 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) Tau95 PF09734.4 ETO17847.1 - 0.073 12.3 0.1 0.22 10.8 0.1 1.7 1 1 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit Mito_fiss_reg PF05308.6 ETO17847.1 - 9.3 5.5 7.2 0.24 10.7 0.2 1.9 3 0 0 3 3 3 0 Mitochondrial fission regulator ABC2_membrane_3 PF12698.2 ETO17850.1 - 0.0012 17.9 0.7 0.0012 17.9 0.5 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein ERM PF00769.14 ETO17850.1 - 0.085 12.3 30.5 1.1 8.7 21.2 2.1 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Reo_sigmaC PF04582.7 ETO17850.1 - 0.17 11.0 1.6 0.29 10.2 1.1 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF3584 PF12128.3 ETO17850.1 - 0.2 8.9 20.6 0.25 8.6 14.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) KxDL PF10241.4 ETO17850.1 - 0.38 10.6 8.7 0.083 12.7 1.4 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF641 PF04859.7 ETO17850.1 - 0.42 10.3 17.6 0.55 9.9 1.5 2.5 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) NPV_P10 PF05531.7 ETO17850.1 - 0.74 10.1 6.4 0.19 12.0 0.5 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Phage_GP20 PF06810.6 ETO17850.1 - 1.4 8.3 28.4 1.2 8.5 6.8 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 CALCOCO1 PF07888.6 ETO17850.1 - 1.5 7.0 22.5 1.8 6.7 15.6 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like TPR_MLP1_2 PF07926.7 ETO17850.1 - 1.8 8.2 26.4 2.7 7.7 5.7 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein REV PF00424.13 ETO17850.1 - 1.9 8.4 5.4 1.4 8.8 1.1 2.2 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Glyco_hydro_67N PF03648.9 ETO17850.1 - 4.1 7.4 8.2 2.8 8.0 1.1 2.5 1 1 1 2 2 2 0 Glycosyl hydrolase family 67 N-terminus Phlebovirus_NSM PF07246.6 ETO17850.1 - 7.1 5.7 17.3 22 4.0 11.5 2.1 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M IncA PF04156.9 ETO17850.1 - 8.1 5.9 32.7 5.3 6.5 10.6 2.5 1 1 1 2 2 2 0 IncA protein DUF4337 PF14235.1 ETO17850.1 - 8.6 6.1 21.2 2.7 7.8 6.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Pox_A_type_inc PF04508.7 ETO17850.1 - 9.8 6.2 11.3 9 6.3 1.5 3.3 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat Pkinase PF00069.20 ETO17852.1 - 1.7e-28 99.5 0.3 6.2e-28 97.6 0.2 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO17852.1 - 4.3e-12 45.6 0.7 1.5e-09 37.2 0.5 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETO17852.1 - 0.0034 17.1 0.0 0.0051 16.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 ETO17852.1 - 0.036 13.3 0.0 0.069 12.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 ETO17852.1 - 0.051 12.6 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2457 PF10446.4 ETO17852.1 - 0.75 8.4 28.3 1.2 7.7 19.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 ETO17852.1 - 1.2 8.6 17.5 0.096 12.1 8.7 1.8 2 0 0 2 2 2 0 Nucleoplasmin Daxx PF03344.10 ETO17852.1 - 1.4 7.3 17.0 2 6.8 11.8 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 ETO17852.1 - 1.5 6.7 15.1 2.3 6.1 10.4 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 ETO17852.1 - 3 6.8 20.1 5.5 5.9 13.9 1.4 1 0 0 1 1 1 0 BUD22 CENP-B_dimeris PF09026.5 ETO17852.1 - 3.7 7.8 14.9 12 6.2 10.3 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4611 PF15387.1 ETO17852.1 - 4.7 7.4 16.9 0.19 11.8 7.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) TFIIF_alpha PF05793.7 ETO17852.1 - 7 4.8 23.7 11 4.1 16.4 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SGT1 PF07093.6 ETO17852.1 - 9 4.5 21.3 15 3.8 14.7 1.2 1 0 0 1 1 1 0 SGT1 protein Med3 PF11593.3 ETO17854.1 - 0.21 10.7 20.6 0.29 10.3 14.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TFIIA PF03153.8 ETO17854.1 - 0.48 10.2 6.1 0.61 9.9 4.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4349 PF14257.1 ETO17854.1 - 3.7 6.6 12.8 6.4 5.9 8.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) CDC45 PF02724.9 ETO17855.1 - 0.0018 16.4 6.2 0.002 16.2 4.3 1.1 1 0 0 1 1 1 1 CDC45-like protein Mem_trans PF03547.13 ETO17855.1 - 0.0099 14.2 0.2 0.012 13.9 0.1 1.2 1 0 0 1 1 1 1 Membrane transport protein BNIP2 PF12496.3 ETO17855.1 - 0.025 14.7 3.4 0.036 14.2 2.4 1.2 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DUF3246 PF11596.3 ETO17855.1 - 0.49 9.6 7.3 0.74 9.0 5.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3246) DUF1510 PF07423.6 ETO17855.1 - 1.1 8.5 14.9 2 7.7 10.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Spt5_N PF11942.3 ETO17855.1 - 1.2 9.8 13.5 2.3 8.9 9.4 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal PUF PF00806.14 ETO17856.1 - 2.3e-42 140.1 4.7 8.2e-08 31.3 0.1 6.3 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat Macoilin PF09726.4 ETO17856.1 - 0.00011 20.6 7.6 0.00015 20.2 5.3 1.3 1 0 0 1 1 1 1 Transmembrane protein DUF3549 PF12069.3 ETO17856.1 - 0.022 13.5 0.4 0.12 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3549) Activator_LAG-3 PF11498.3 ETO17856.1 - 2.1 6.9 16.0 5.4 5.6 11.1 1.7 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Pol_alpha_B_N PF08418.5 ETO17856.1 - 2.2 7.7 8.6 4.2 6.8 5.9 1.5 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal RAP1 PF07218.6 ETO17856.1 - 8.1 4.4 17.5 12 3.8 12.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pex14_N PF04695.8 ETO17856.1 - 8.7 6.3 12.4 4.2 7.4 3.1 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2101 PF09874.4 ETO17858.1 - 0.024 14.1 0.8 0.024 14.1 0.6 1.9 2 1 1 3 3 3 0 Predicted membrane protein (DUF2101) IFT46_B_C PF12317.3 ETO17859.1 - 6.3e-62 208.7 5.8 6.3e-62 208.7 4.0 1.8 2 0 0 2 2 2 1 Intraflagellar transport complex B protein 46 C terminal Ank_2 PF12796.2 ETO17860.1 - 2.1e-33 114.4 15.1 1.5e-16 60.4 1.2 2.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETO17860.1 - 8.2e-20 69.5 2.3 3.5e-07 29.6 0.1 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 ETO17860.1 - 3e-19 68.9 1.3 3.9e-06 27.2 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO17860.1 - 1e-15 56.2 4.8 0.00086 19.3 0.2 4.7 3 1 1 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 ETO17860.1 - 2.1e-13 50.0 6.2 3.3e-06 27.1 0.1 3.3 1 1 3 4 4 4 3 Ankyrin repeats (many copies) DUF1968 PF09291.5 ETO17861.1 - 0.011 15.5 3.7 0.018 14.8 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1968) THP2 PF09432.5 ETO17863.1 - 0.047 13.5 0.1 0.11 12.4 0.1 1.7 1 1 0 1 1 1 0 Tho complex subunit THP2 G-alpha PF00503.15 ETO17866.1 - 8.8e-12 44.3 0.0 1.5e-11 43.6 0.0 1.4 1 1 0 1 1 1 1 G-protein alpha subunit zf-4CXXC_R1 PF10497.4 ETO17867.1 - 0.023 14.8 21.4 0.097 12.8 5.9 2.3 1 1 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Spc7 PF08317.6 ETO17868.1 - 0.00036 19.2 2.3 0.00055 18.7 1.6 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein CCDC155 PF14662.1 ETO17868.1 - 0.00051 19.6 0.7 0.00086 18.9 0.5 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 CENP-F_leu_zip PF10473.4 ETO17868.1 - 0.001 18.9 3.8 0.001 18.9 2.6 1.5 2 0 0 2 2 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF342 PF03961.8 ETO17868.1 - 0.0054 15.2 1.7 0.008 14.6 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF342) IncA PF04156.9 ETO17868.1 - 0.0054 16.3 4.7 0.0054 16.3 3.3 1.4 2 0 0 2 2 2 1 IncA protein Macoilin PF09726.4 ETO17868.1 - 0.0088 14.3 8.7 0.01 14.1 6.0 1.1 1 0 0 1 1 1 1 Transmembrane protein TBPIP PF07106.8 ETO17868.1 - 0.014 14.9 4.3 0.029 13.9 3.0 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF812 PF05667.6 ETO17868.1 - 0.015 13.8 7.1 0.018 13.6 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF3972 PF13118.1 ETO17868.1 - 0.018 15.1 4.7 0.042 13.9 3.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3972) DUF3373 PF11853.3 ETO17868.1 - 0.03 12.8 0.7 0.044 12.3 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) PilJ PF13675.1 ETO17868.1 - 0.039 14.2 0.9 0.081 13.2 0.6 1.5 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term V_ATPase_I PF01496.14 ETO17868.1 - 0.048 11.5 2.9 0.08 10.7 2.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Imm46 PF15585.1 ETO17868.1 - 0.13 12.3 0.5 0.34 10.9 0.1 1.8 2 0 0 2 2 2 0 Immunity protein 46 DUF4164 PF13747.1 ETO17868.1 - 0.15 12.2 3.7 0.24 11.5 1.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Prefoldin PF02996.12 ETO17868.1 - 0.15 11.6 6.7 0.25 10.9 3.2 2.1 2 0 0 2 2 2 0 Prefoldin subunit SseC PF04888.7 ETO17868.1 - 0.16 11.2 0.9 0.19 11.0 0.6 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Kinesin-relat_1 PF12711.2 ETO17868.1 - 0.16 12.3 7.3 1.6 9.1 0.4 2.4 1 1 1 2 2 2 0 Kinesin motor Atg14 PF10186.4 ETO17868.1 - 0.21 10.4 18.2 0.17 10.7 11.0 1.8 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Cep57_MT_bd PF06657.8 ETO17868.1 - 0.38 10.7 4.6 0.22 11.4 0.5 2.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 APG6 PF04111.7 ETO17868.1 - 0.61 9.0 10.0 0.017 14.2 2.7 1.4 2 0 0 2 2 2 0 Autophagy protein Apg6 ATG16 PF08614.6 ETO17868.1 - 0.69 9.7 11.9 1.2 8.9 8.3 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Med9 PF07544.8 ETO17868.1 - 0.76 9.5 8.4 0.71 9.6 3.3 2.4 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DivIVA PF05103.8 ETO17868.1 - 0.89 9.6 10.9 0.082 12.9 3.4 2.1 2 0 0 2 2 2 0 DivIVA protein Fib_alpha PF08702.5 ETO17868.1 - 0.9 9.6 9.6 0.051 13.6 1.8 2.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Lzipper-MIP1 PF14389.1 ETO17868.1 - 1.1 9.3 8.4 1.7 8.8 3.4 2.3 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF4140 PF13600.1 ETO17868.1 - 4.9 7.6 7.8 0.6 10.5 1.9 2.1 2 2 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Macoilin PF09726.4 ETO17870.1 - 0.044 12.0 5.9 0.054 11.7 4.1 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF588 PF04535.7 ETO17871.1 - 0.27 10.8 0.1 0.27 10.8 0.1 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF588) DUF3329 PF11808.3 ETO17871.1 - 5.9 7.0 6.2 5.3 7.2 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) Ribosomal_L6 PF00347.18 ETO17872.1 - 0.12 12.9 0.2 1.3 9.6 0.1 2.5 1 1 2 3 3 3 0 Ribosomal protein L6 SIS PF01380.17 ETO17874.1 - 9.2e-26 89.9 1.9 3.5e-13 49.2 0.3 2.3 2 0 0 2 2 2 2 SIS domain GATase_7 PF13537.1 ETO17875.1 - 1.1e-06 28.3 0.0 4.1e-06 26.5 0.0 1.8 1 1 1 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 ETO17875.1 - 0.00015 21.7 0.0 0.00021 21.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase domain CAML PF14963.1 ETO17876.1 - 0.019 14.3 0.3 0.11 11.8 0.0 1.9 1 1 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand SICA_beta PF12878.2 ETO17876.1 - 0.28 10.9 5.0 0.61 9.8 3.5 1.5 1 1 0 1 1 1 0 SICA extracellular beta domain FF PF01846.14 ETO17878.1 - 1.3e-05 25.0 0.1 3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 FF domain GHL12 PF14882.1 ETO17878.1 - 0.047 13.7 0.3 0.087 12.9 0.2 1.5 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 12 Med21 PF11221.3 ETO17878.1 - 0.11 12.4 2.8 0.12 12.3 1.8 1.2 1 1 0 1 1 1 0 Subunit 21 of Mediator complex DUF2031 PF09592.5 ETO17878.1 - 0.34 10.0 3.7 0.43 9.6 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) WGR PF05406.10 ETO17878.1 - 1.5 8.7 5.2 1.8 8.5 0.1 2.2 2 0 0 2 2 2 0 WGR domain ATP-synt_E PF05680.7 ETO17878.1 - 4.4 7.3 9.8 1.5 8.8 4.0 1.9 2 0 0 2 2 2 0 ATP synthase E chain Neur_chan_memb PF02932.11 ETO17880.1 - 0.086 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Mucin PF01456.12 ETO17880.1 - 0.094 12.4 0.8 0.15 11.8 0.6 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein TIMELESS_C PF05029.8 ETO17880.1 - 3 6.6 15.6 1.2 7.9 3.9 3.0 2 1 1 3 3 3 0 Timeless protein C terminal region PBP1_TM PF14812.1 ETO17880.1 - 4 7.8 6.3 0.56 10.5 1.0 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Trypan_PARP PF05887.6 ETO17881.1 - 0.014 15.2 18.5 0.014 15.2 12.9 4.1 3 1 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) EF-hand_7 PF13499.1 ETO17881.1 - 0.018 15.1 0.2 0.065 13.3 0.0 2.0 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.27 ETO17881.1 - 0.045 13.0 0.0 0.086 12.1 0.0 1.4 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 ETO17881.1 - 0.063 13.1 0.1 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain DUF680 PF05079.7 ETO17882.1 - 0.036 14.5 0.3 0.036 14.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF680) TraG-D_C PF12696.2 ETO17882.1 - 0.23 11.3 5.6 0.09 12.6 1.0 2.2 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG MRP PF09387.5 ETO17883.1 - 6.5 6.4 13.6 0.64 9.7 6.1 1.8 2 0 0 2 2 2 0 Mitochondrial RNA binding protein MRP Peptidase_U57 PF05582.7 ETO17883.1 - 9.9 5.0 12.3 0.055 12.4 1.2 2.0 2 0 0 2 2 2 0 YabG peptidase U57 uDENN PF03456.13 ETO17884.1 - 6.2e-11 42.1 1.0 1.2e-10 41.1 0.7 1.5 1 0 0 1 1 1 1 uDENN domain Dicty_REP PF05086.7 ETO17884.1 - 2.1 6.0 5.3 2.3 5.8 3.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 ETO17884.1 - 3.7 7.3 17.9 4.6 7.0 12.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Ank_2 PF12796.2 ETO17885.1 - 2.1e-06 27.9 0.3 0.059 13.7 0.1 3.8 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETO17885.1 - 2.9e-05 23.6 0.0 1.6 8.6 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 ETO17885.1 - 7.2e-05 23.1 0.2 1.1 9.9 0.0 4.5 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO17885.1 - 9.5e-05 22.5 0.0 0.26 11.5 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeats (many copies) DUF2254 PF10011.4 ETO17886.1 - 0.068 11.6 0.2 0.068 11.6 0.1 1.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2254) LMBR1 PF04791.11 ETO17886.1 - 0.14 10.6 5.1 0.23 9.9 3.6 1.3 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF4659 PF15558.1 ETO17886.1 - 0.32 9.6 14.4 0.49 9.0 10.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4659) RRN3 PF05327.6 ETO17886.1 - 2 6.4 9.7 3 5.8 6.7 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Rootletin PF15035.1 ETO17887.1 - 3.5e-05 23.8 18.0 3.5e-05 23.8 12.5 2.6 1 1 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion Cast PF10174.4 ETO17887.1 - 0.002 16.2 34.1 0.0025 15.9 23.6 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone DUF972 PF06156.8 ETO17887.1 - 0.0057 16.9 36.4 0.026 14.8 11.8 3.2 1 1 1 2 2 2 1 Protein of unknown function (DUF972) MAD PF05557.8 ETO17887.1 - 0.017 13.2 33.5 0.024 12.7 23.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein TMF_TATA_bd PF12325.3 ETO17887.1 - 0.035 13.8 38.8 0.15 11.8 4.7 3.3 1 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding GAS PF13851.1 ETO17887.1 - 0.11 11.6 42.0 0.065 12.4 12.1 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.6 ETO17887.1 - 0.24 11.2 38.9 0.51 10.1 5.8 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) APG6 PF04111.7 ETO17887.1 - 0.33 9.9 43.6 0.41 9.6 13.3 2.7 1 1 2 3 3 3 0 Autophagy protein Apg6 TBPIP PF07106.8 ETO17887.1 - 0.58 9.6 39.1 1.3 8.5 10.5 3.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) YlqD PF11068.3 ETO17887.1 - 0.88 9.6 38.7 2.3 8.2 9.8 2.8 2 1 0 2 2 2 0 YlqD protein Golgin_A5 PF09787.4 ETO17887.1 - 1.4 7.3 37.2 2.7 6.4 8.5 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF4200 PF13863.1 ETO17887.1 - 2.2 8.2 44.0 1.2 9.1 11.8 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) IncA PF04156.9 ETO17887.1 - 2.3 7.7 47.7 1.7 8.1 13.0 3.2 1 1 1 2 2 2 0 IncA protein TPR_MLP1_2 PF07926.7 ETO17887.1 - 2.6 7.7 43.1 1.1 9.0 12.2 2.8 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 ETO17887.1 - 3.5 7.5 39.7 0.33 10.7 9.9 3.4 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF1675 PF07897.6 ETO17887.1 - 4.4 7.0 10.0 5.9 6.6 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Tropomyosin_1 PF12718.2 ETO17887.1 - 4.8 7.0 45.7 2.2 8.1 14.4 2.5 1 1 0 2 2 2 0 Tropomyosin like Mnd1 PF03962.10 ETO17887.1 - 5.2 6.7 34.9 1.8 8.1 10.5 2.7 1 1 1 2 2 2 0 Mnd1 family Cluap1 PF10234.4 ETO17887.1 - 8.4 5.5 30.6 3.2 6.8 9.9 2.5 1 1 1 2 2 2 0 Clusterin-associated protein-1 bZIP_1 PF00170.16 ETO17887.1 - 9.4 6.2 38.5 0.11 12.4 4.4 5.2 3 2 3 6 6 6 0 bZIP transcription factor Colicin-DNase PF12639.2 ETO17890.1 - 0.011 16.0 1.5 0.018 15.2 1.1 1.4 1 0 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin FUSC_2 PF13515.1 ETO17891.1 - 0.0041 17.0 1.9 0.0059 16.5 1.3 1.2 1 0 0 1 1 1 1 Fusaric acid resistance protein-like B-block_TFIIIC PF04182.7 ETO17891.1 - 0.11 12.3 0.5 0.34 10.7 0.2 1.9 1 1 1 2 2 2 0 B-block binding subunit of TFIIIC CSD PF00313.17 ETO17891.1 - 0.16 11.7 1.4 0.2 11.4 0.3 1.7 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain FKBP_C PF00254.23 ETO17893.1 - 7.1e-12 45.1 0.0 1.6e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EphA2_TM PF14575.1 ETO17894.1 - 0.0045 17.3 0.6 1.4 9.3 0.2 2.8 2 1 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain DUF4330 PF14221.1 ETO17894.1 - 0.007 16.2 0.4 0.01 15.6 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4330) Orthoreo_P10 PF07204.6 ETO17894.1 - 0.0075 15.9 1.7 0.0085 15.8 0.6 1.6 1 1 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 TMEM51 PF15345.1 ETO17894.1 - 0.0079 15.9 1.7 0.013 15.1 0.1 1.7 1 1 0 2 2 2 1 Transmembrane protein 51 DUF1191 PF06697.7 ETO17894.1 - 0.03 13.1 3.0 0.35 9.6 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1191) UPF0104 PF03706.8 ETO17894.1 - 0.033 13.4 0.2 0.051 12.8 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) Herpes_gE PF02480.11 ETO17894.1 - 0.044 12.0 0.0 0.053 11.7 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E MLANA PF14991.1 ETO17894.1 - 0.086 12.8 0.1 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein melan-A DUF1469 PF07332.6 ETO17894.1 - 0.14 11.9 0.6 0.29 10.8 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) PIRT PF15099.1 ETO17894.1 - 2.9 7.1 6.8 3.3 6.9 0.7 2.7 2 1 0 2 2 2 0 Phosphoinositide-interacting protein family V-ATPase_H_N PF03224.9 ETO17895.1 - 5.6e-11 42.1 0.0 8e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H OppC_N PF12911.2 ETO17896.1 - 0.36 10.2 0.1 0.36 10.2 0.1 2.1 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C zf-C2H2 PF00096.21 ETO17897.1 - 4.9e-06 26.5 23.2 0.011 16.0 1.4 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETO17897.1 - 2.9e-05 24.1 19.2 0.064 13.6 0.8 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETO17897.1 - 0.00078 19.6 0.1 0.00078 19.6 0.1 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 ETO17897.1 - 0.0044 17.1 0.1 0.0044 17.1 0.1 3.9 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 ETO17897.1 - 0.033 14.4 0.6 0.033 14.4 0.4 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type FYVE PF01363.16 ETO17897.1 - 1.1 9.1 9.6 2.6 8.0 6.7 1.8 1 1 0 1 1 1 0 FYVE zinc finger zf-C2H2_6 PF13912.1 ETO17897.1 - 1.6 8.7 18.7 1.4 8.9 1.8 4.0 3 1 0 3 3 3 0 C2H2-type zinc finger DUF1677 PF07911.8 ETO17897.1 - 2.6 8.2 5.1 6.3 7.0 1.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1677) zf-C2H2_2 PF12756.2 ETO17897.1 - 3.8 7.6 14.2 21 5.3 9.5 2.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) F-box-like PF12937.2 ETO17899.1 - 7.5e-07 28.7 0.8 7.5e-07 28.7 0.5 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 ETO17899.1 - 9.4e-05 21.9 1.9 0.00034 20.1 1.3 1.9 1 1 0 1 1 1 1 F-box domain EndIII_4Fe-2S PF10576.4 ETO17899.1 - 0.1 12.8 1.4 0.21 11.8 1.0 1.6 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III AIF_C PF14721.1 ETO17899.1 - 0.71 10.1 3.2 0.55 10.4 0.1 2.0 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Autophagy_N PF03986.8 ETO17899.1 - 1.6 8.5 8.1 0.36 10.6 2.8 1.8 2 0 0 2 2 2 0 Autophagocytosis associated protein (Atg3), N-terminal domain NPR3 PF03666.8 ETO17899.1 - 6 5.2 8.1 7.6 4.9 5.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Ank_2 PF12796.2 ETO17900.1 - 0.00039 20.7 0.0 0.0019 18.4 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) GGDEF PF00990.16 ETO17900.1 - 0.018 14.6 0.0 0.16 11.5 0.0 2.2 1 1 0 1 1 1 0 GGDEF domain Ank_4 PF13637.1 ETO17900.1 - 0.028 14.9 0.3 0.48 11.0 0.0 2.8 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Phage_min_tail PF05939.8 ETO17900.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Phage minor tail protein LRRNT_2 PF08263.7 ETO17901.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Exo_endo_phos_2 PF14529.1 ETO17901.1 - 0.13 11.8 0.1 0.22 11.1 0.1 1.4 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase XAP5 PF04921.9 ETO17903.1 - 0.096 12.2 21.3 0.74 9.3 7.7 2.1 2 0 0 2 2 2 0 XAP5, circadian clock regulator Apc15p PF05841.6 ETO17903.1 - 1.1 9.9 15.7 8.3 7.1 7.7 2.1 2 0 0 2 2 2 0 Apc15p protein Nucleoside_tran PF01733.13 ETO17903.1 - 1.6 7.8 5.5 0.84 8.7 0.1 2.0 2 0 0 2 2 2 0 Nucleoside transporter CDC45 PF02724.9 ETO17903.1 - 1.7 6.5 18.2 0.03 12.3 7.0 1.8 2 0 0 2 2 2 0 CDC45-like protein DUF2201_N PF13203.1 ETO17903.1 - 3.3 6.8 17.7 0.059 12.5 6.6 1.8 1 1 1 2 2 2 0 Putative metallopeptidase domain Vfa1 PF08432.5 ETO17903.1 - 9 6.2 19.7 3.7 7.5 6.1 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 RR_TM4-6 PF06459.7 ETO17903.1 - 9.4 6.0 14.3 0.9 9.3 3.6 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Chromo PF00385.19 ETO17905.1 - 3.7e-07 29.7 1.3 1.1e-06 28.1 0.9 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain TFIIF_alpha PF05793.7 ETO17905.1 - 0.001 17.5 8.8 0.0012 17.2 6.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Rubredoxin PF00301.15 ETO17905.1 - 0.0077 16.0 1.7 0.76 9.7 0.1 2.9 2 1 0 2 2 2 1 Rubredoxin Daxx PF03344.10 ETO17905.1 - 0.03 12.8 6.9 0.036 12.5 4.8 1.3 1 0 0 1 1 1 0 Daxx Family Git3_C PF11970.3 ETO17905.1 - 0.084 12.6 1.1 0.18 11.6 0.2 2.0 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term Enterotoxin_ST PF02048.11 ETO17905.1 - 0.12 12.6 1.5 0.4 10.9 1.0 1.9 1 0 0 1 1 1 0 Heat-stable enterotoxin ST PHD PF00628.24 ETO17905.1 - 0.26 11.0 7.0 4.3 7.0 0.2 2.7 2 0 0 2 2 2 0 PHD-finger CENP-T PF15511.1 ETO17905.1 - 0.96 8.6 5.3 1.2 8.2 3.7 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CDC45 PF02724.9 ETO17905.1 - 1.1 7.2 8.8 1.6 6.6 6.1 1.2 1 0 0 1 1 1 0 CDC45-like protein SET PF00856.23 ETO17906.1 - 9.2e-06 26.0 0.0 4.2e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 SET domain DUF479 PF04336.7 ETO17908.1 - 0.2 11.7 1.9 1.8 8.7 0.0 2.9 2 1 0 3 3 3 0 Protein of unknown function, DUF479 CLASP_N PF12348.3 ETO17909.1 - 2.9e-11 43.1 3.1 4.1e-11 42.6 2.2 1.1 1 0 0 1 1 1 1 CLASP N terminal Vac14_Fab1_bd PF12755.2 ETO17909.1 - 0.023 15.0 1.2 1.1 9.6 0.1 3.0 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region DUF1981 PF09324.5 ETO17909.1 - 0.19 11.3 0.1 0.19 11.3 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) DUF3453 PF11935.3 ETO17909.1 - 0.29 10.5 5.3 0.25 10.7 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3453) RasGAP PF00616.14 ETO17909.1 - 7.9 6.0 11.2 7.4 6.1 6.5 1.9 1 1 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase FISNA PF14484.1 ETO17910.1 - 0.11 12.5 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 Fish-specific NACHT associated domain CBP4 PF07960.6 ETO17910.1 - 0.26 10.9 7.6 0.057 13.0 2.1 1.8 1 1 1 2 2 2 0 CBP4 IMD PF08397.6 ETO17910.1 - 1.3 8.2 5.0 23 4.2 3.4 2.1 1 1 0 1 1 1 0 IRSp53/MIM homology domain DNA_binding_1 PF01035.15 ETO17912.1 - 2.4e-20 72.0 0.0 7.9e-19 67.1 0.0 2.3 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Sel1 PF08238.7 ETO17913.1 - 4.9e-06 26.9 11.8 0.037 14.6 0.1 4.8 5 0 0 5 5 5 3 Sel1 repeat Sulfatase PF00884.18 ETO17914.1 - 0.00091 18.4 0.1 0.018 14.2 0.0 2.1 2 0 0 2 2 2 1 Sulfatase Sulfatase_C PF14707.1 ETO17914.1 - 0.01 16.0 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase Kelch_2 PF07646.10 ETO17916.1 - 0.11 12.2 0.8 0.9 9.4 0.2 2.8 3 0 0 3 3 3 0 Kelch motif Prion PF00377.13 ETO17917.1 - 0.03 14.0 0.6 0.03 14.0 0.4 2.7 2 1 0 2 2 2 0 Prion/Doppel alpha-helical domain Gly-zipper_Omp PF13488.1 ETO17918.1 - 2.7e-07 30.0 28.0 0.00083 18.9 4.1 3.7 2 1 1 3 3 3 2 Glycine zipper Gly-zipper_YMGG PF13441.1 ETO17918.1 - 4.4e-06 26.0 20.6 0.012 15.0 1.0 3.9 3 2 0 3 3 3 2 YMGG-like Gly-zipper Bacteriocin_IIc PF10439.4 ETO17918.1 - 0.0036 17.3 32.6 1.5e+04 -5.2 22.6 3.7 1 1 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Rick_17kDa_Anti PF05433.10 ETO17918.1 - 0.021 14.4 37.8 0.063 12.9 10.7 4.4 2 1 1 3 3 3 0 Glycine zipper 2TM domain TraT PF05818.7 ETO17918.1 - 0.037 13.4 12.9 0.6 9.5 0.7 2.6 1 1 2 3 3 3 0 Enterobacterial TraT complement resistance protein Gly-zipper_OmpA PF13436.1 ETO17918.1 - 0.062 12.9 18.7 0.22 11.1 2.2 2.8 1 1 1 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain DUF456 PF04306.8 ETO17918.1 - 0.14 12.1 39.1 1.5e+04 -14.4 27.1 3.8 1 1 0 1 1 1 0 Protein of unknown function (DUF456) MscL PF01741.13 ETO17918.1 - 0.17 12.0 14.5 0.66 10.1 2.6 2.6 1 1 3 4 4 4 0 Large-conductance mechanosensitive channel, MscL DUF1269 PF06897.7 ETO17918.1 - 9.9 6.2 29.5 0.8 9.7 5.1 3.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1269) DEAD PF00270.24 ETO17919.1 - 8.5e-08 31.8 0.0 1e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.1 ETO17919.1 - 2.4e-05 23.9 0.0 3.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Part of AAA domain AAA_29 PF13555.1 ETO17919.1 - 0.00052 19.4 0.0 0.00077 18.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain UvrD-helicase PF00580.16 ETO17919.1 - 0.00096 18.5 0.0 0.0011 18.3 0.0 1.1 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain PhoH PF02562.11 ETO17919.1 - 0.0071 15.5 0.0 0.0097 15.1 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein AAA_16 PF13191.1 ETO17919.1 - 0.0072 16.3 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.1 ETO17919.1 - 0.012 15.1 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 ETO17919.1 - 0.02 15.1 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter ResIII PF04851.10 ETO17919.1 - 0.036 13.9 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ATP-synt_ab PF00006.20 ETO17919.1 - 0.052 13.0 0.0 0.069 12.6 0.0 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Terminase_GpA PF05876.7 ETO17919.1 - 0.06 11.7 0.0 0.076 11.3 0.0 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Terminase_6 PF03237.10 ETO17919.1 - 0.092 11.4 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Terminase-like family TPR_11 PF13414.1 ETO17921.1 - 8.6e-11 41.3 2.3 6.2e-06 25.7 0.3 2.5 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETO17921.1 - 2.6e-09 36.3 10.1 2.2e-05 23.8 0.5 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat DnaJ PF00226.26 ETO17921.1 - 6.6e-09 35.3 1.6 6.6e-09 35.3 1.1 2.7 1 1 1 2 2 2 1 DnaJ domain TPR_2 PF07719.12 ETO17921.1 - 1.3e-08 34.0 7.1 7.2e-06 25.5 0.9 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO17921.1 - 1.5e-07 31.8 1.1 0.00019 22.0 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO17921.1 - 3.9e-05 23.5 1.1 0.0002 21.2 0.0 2.7 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO17921.1 - 0.00016 21.5 2.0 0.05 13.5 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO17921.1 - 0.0012 19.3 3.1 0.089 13.4 0.2 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat PPP5 PF08321.7 ETO17921.1 - 0.0093 15.9 0.8 0.043 13.8 0.1 2.2 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_19 PF14559.1 ETO17921.1 - 0.016 15.5 1.6 0.25 11.6 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETO17921.1 - 0.028 14.1 5.6 0.44 10.4 0.1 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO17921.1 - 0.041 14.3 0.4 0.3 11.6 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETO17921.1 - 0.072 12.9 1.4 1 9.3 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 ETO17921.1 - 0.087 12.7 1.9 4.8 7.1 0.0 2.9 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain ST7 PF04184.7 ETO17921.1 - 0.2 9.8 3.2 0.23 9.6 2.2 1.1 1 0 0 1 1 1 0 ST7 protein Rho_Binding PF08912.6 ETO17921.1 - 1.9 8.8 7.8 0.39 11.0 1.3 2.8 1 1 1 2 2 2 0 Rho Binding HECT PF00632.20 ETO17922.1 - 1.5e-86 290.4 0.0 1.5e-86 290.4 0.0 1.8 2 1 0 2 2 2 1 HECT-domain (ubiquitin-transferase) CobT PF06213.7 ETO17924.1 - 0.18 10.9 6.4 0.24 10.5 4.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2076 PF09849.4 ETO17924.1 - 0.91 9.5 12.8 1.3 9.0 8.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF2457 PF10446.4 ETO17924.1 - 1.3 7.6 9.5 1.7 7.2 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.7 ETO17924.1 - 1.4 8.1 8.4 1.8 7.7 5.8 1.1 1 0 0 1 1 1 0 SDA1 FimP PF09766.4 ETO17924.1 - 5.1 6.0 10.5 3.1 6.7 6.5 1.3 1 1 0 1 1 1 0 Fms-interacting protein CENP-B_dimeris PF09026.5 ETO17924.1 - 6.4 7.0 7.9 11 6.3 5.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PI3_PI4_kinase PF00454.22 ETO17925.1 - 0.043 13.2 0.0 0.057 12.8 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase ERF PF04404.7 ETO17925.1 - 0.18 11.3 2.2 0.2 11.1 0.8 1.7 2 0 0 2 2 2 0 ERF superfamily Pox_G5 PF04599.7 ETO17926.1 - 0.0038 15.9 1.7 0.0042 15.8 1.2 1.2 1 0 0 1 1 1 1 Poxvirus G5 protein SMN PF06003.7 ETO17926.1 - 5 6.1 6.9 4.3 6.3 4.1 1.4 1 1 0 1 1 1 0 Survival motor neuron protein (SMN) VWA_2 PF13519.1 ETO17928.1 - 3.5e-05 23.9 0.1 0.00012 22.2 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain UCH PF00443.24 ETO17929.1 - 1.5e-18 66.9 0.7 6.9e-18 64.7 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase NTP_transf_5 PF14907.1 ETO17930.1 - 0.091 12.0 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised nucleotidyltransferase DNA_pol_A_exo1 PF01612.15 ETO17931.1 - 0.00049 19.6 4.1 0.0088 15.5 0.2 3.2 3 1 0 3 3 3 2 3'-5' exonuclease HTH_40 PF14493.1 ETO17931.1 - 0.05 13.8 0.4 3.6 7.8 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain fn3 PF00041.16 ETO17932.1 - 9.3e-05 22.4 1.7 0.042 13.9 1.2 2.4 1 1 0 1 1 1 1 Fibronectin type III domain CDC45 PF02724.9 ETO17932.1 - 0.038 12.0 15.6 0.04 11.9 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein CENP-T PF15511.1 ETO17932.1 - 0.12 11.5 6.6 0.12 11.5 4.5 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 ETO17932.1 - 0.17 9.7 21.5 0.18 9.7 14.9 1.2 1 0 0 1 1 1 0 Nop14-like family Spore_coat_CotO PF14153.1 ETO17932.1 - 0.22 10.9 15.4 0.14 11.5 9.6 1.4 1 1 0 1 1 1 0 Spore coat protein CotO DUF2457 PF10446.4 ETO17932.1 - 0.55 8.8 22.7 0.68 8.5 15.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RRN3 PF05327.6 ETO17932.1 - 3.4 5.6 11.1 3.7 5.5 7.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Astro_capsid PF03115.9 ETO17932.1 - 3.8 5.6 11.6 4.2 5.4 8.0 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Daxx PF03344.10 ETO17932.1 - 5.9 5.2 21.7 6.2 5.1 15.1 1.0 1 0 0 1 1 1 0 Daxx Family eIF-3_zeta PF05091.7 ETO17933.1 - 5.2e-09 35.2 0.4 6e-09 35.0 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Daxx PF03344.10 ETO17934.1 - 0.13 10.7 17.0 0.14 10.6 11.8 1.1 1 0 0 1 1 1 0 Daxx Family HECT_2 PF09814.4 ETO17935.1 - 0.00049 18.9 0.5 0.00062 18.5 0.4 1.1 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Baculo_11_kDa PF06143.6 ETO17935.1 - 0.02 14.2 5.9 0.056 12.8 4.1 1.8 1 0 0 1 1 1 0 Baculovirus 11 kDa family Tetraspannin PF00335.15 ETO17935.1 - 0.039 13.2 0.9 0.045 13.0 0.6 1.3 1 1 0 1 1 1 0 Tetraspanin family DUF4446 PF14584.1 ETO17935.1 - 0.041 13.7 2.2 0.079 12.7 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) 7tm_2 PF00002.19 ETO17935.1 - 0.097 11.7 5.8 1.9 7.4 0.0 2.2 2 0 0 2 2 2 0 7 transmembrane receptor (Secretin family) TMEM154 PF15102.1 ETO17935.1 - 0.24 11.1 6.9 0.58 9.8 4.8 1.7 1 0 0 1 1 1 0 TMEM154 protein family HemY_N PF07219.8 ETO17935.1 - 0.46 10.0 3.0 0.87 9.1 2.0 1.4 1 0 0 1 1 1 0 HemY protein N-terminus HN PF00423.14 ETO17935.1 - 0.55 8.4 7.7 0.59 8.3 4.6 1.5 2 0 0 2 2 2 0 Haemagglutinin-neuraminidase EphA2_TM PF14575.1 ETO17935.1 - 0.75 10.2 5.2 0.16 12.4 0.8 2.1 3 0 0 3 3 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1312 PF07009.6 ETO17935.1 - 1.5 8.6 10.6 30 4.4 5.8 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1312) DUF3139 PF11337.3 ETO17935.1 - 2.8 8.2 8.9 3.6 7.9 4.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Tmemb_9 PF05434.6 ETO17935.1 - 3.2 7.4 9.8 0.44 10.2 3.6 1.9 2 0 0 2 2 2 0 TMEM9 DUF2615 PF11027.3 ETO17935.1 - 3.4 7.6 5.2 0.95 9.4 0.6 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2615) AJAP1_PANP_C PF15298.1 ETO17935.1 - 3.6 7.4 5.4 6.9 6.5 3.7 1.4 1 0 0 1 1 1 0 AJAP1/PANP C-terminus ABC2_membrane_3 PF12698.2 ETO17937.1 - 2.2e-27 95.9 27.6 2.2e-27 95.9 19.1 2.0 2 0 0 2 2 2 1 ABC-2 family transporter protein Epsilon_antitox PF08998.6 ETO17940.1 - 0.3 11.0 2.9 3.7 7.5 0.0 3.0 2 1 1 3 3 3 0 Bacterial epsilon antitoxin WD40 PF00400.27 ETO17941.1 - 8.3e-46 152.3 10.1 1.2e-12 47.1 0.3 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO17941.1 - 4.1e-08 33.1 0.0 6.4e-07 29.2 0.0 2.5 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 ETO17941.1 - 0.00037 19.3 0.2 0.00068 18.4 0.1 1.4 1 1 0 1 1 1 1 Nup133 N terminal like Nup160 PF11715.3 ETO17941.1 - 0.00048 18.3 0.6 0.24 9.5 0.0 3.2 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Hira PF07569.6 ETO17941.1 - 0.023 13.8 0.1 1.2 8.3 0.0 2.4 2 0 0 2 2 2 0 TUP1-like enhancer of split PQQ_2 PF13360.1 ETO17941.1 - 0.061 12.7 0.1 10 5.4 0.0 2.2 1 1 1 2 2 2 0 PQQ-like domain B3_4 PF03483.12 ETO17941.1 - 0.12 11.8 0.0 0.65 9.4 0.0 2.2 2 1 1 3 3 3 0 B3/4 domain PD40 PF07676.7 ETO17941.1 - 0.14 11.8 0.2 8.9 6.0 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF2140 PF09911.4 ETO17942.1 - 0.011 14.9 0.1 0.012 14.7 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF2393 PF09624.5 ETO17942.1 - 0.025 14.1 0.3 0.03 13.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) DUF4199 PF13858.1 ETO17942.1 - 0.029 14.2 0.1 0.029 14.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Tetraspannin PF00335.15 ETO17942.1 - 0.048 12.9 0.8 0.052 12.8 0.5 1.1 1 0 0 1 1 1 0 Tetraspanin family Fijivirus_P9-2 PF06837.6 ETO17942.1 - 0.051 12.6 6.3 0.052 12.6 4.4 1.0 1 0 0 1 1 1 0 Fijivirus P9-2 protein DUF3357 PF11837.3 ETO17942.1 - 0.1 12.4 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) UcrQ PF02939.11 ETO17942.1 - 0.12 12.1 1.6 0.15 11.9 1.1 1.1 1 0 0 1 1 1 0 UcrQ family Ion_trans PF00520.26 ETO17942.1 - 0.47 9.6 5.5 0.59 9.3 3.8 1.1 1 0 0 1 1 1 0 Ion transport protein zf-DHHC PF01529.15 ETO17942.1 - 0.61 9.4 4.9 0.71 9.2 3.4 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase ETRAMP PF09716.5 ETO17942.1 - 1.1 9.2 3.4 1.4 8.8 2.3 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) EF-hand_1 PF00036.27 ETO17943.1 - 2e-24 82.9 4.6 5e-08 31.6 0.1 5.1 4 1 1 5 5 5 3 EF hand EF-hand_7 PF13499.1 ETO17943.1 - 3.8e-24 84.5 4.5 1.9e-15 56.7 0.2 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 ETO17943.1 - 1.3e-19 69.4 6.5 9.7e-08 31.5 0.1 4.2 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 ETO17943.1 - 1.6e-17 61.9 10.1 9.6e-06 24.7 0.1 5.1 5 1 1 6 6 6 3 EF hand EF-hand_6 PF13405.1 ETO17943.1 - 5.5e-17 60.0 6.1 1.9e-05 24.1 0.0 5.6 4 1 1 5 5 5 3 EF-hand domain SPARC_Ca_bdg PF10591.4 ETO17943.1 - 9.8e-08 32.0 0.0 0.00016 21.6 0.0 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 ETO17943.1 - 3.6e-05 23.5 0.1 0.01 15.7 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.2 ETO17943.1 - 0.0034 17.0 0.1 0.1 12.3 0.0 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_like PF09279.6 ETO17943.1 - 0.005 16.8 0.5 3.4 7.7 0.0 3.2 3 0 0 3 3 3 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_10 PF14788.1 ETO17943.1 - 0.039 13.6 0.2 9.4 5.9 0.0 3.3 3 1 0 3 3 3 0 EF hand DUF3349 PF11829.3 ETO17943.1 - 0.11 12.9 0.0 25 5.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) Leucyl-specific PF14795.1 ETO17943.1 - 0.11 12.3 1.2 5.4 6.9 0.0 3.2 4 0 0 4 4 4 0 Leucine-tRNA synthetase-specific domain VKG_Carbox PF05090.9 ETO17944.1 - 0.65 8.7 2.9 0.88 8.3 2.0 1.1 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase Mg_chelatase PF01078.16 ETO17945.1 - 4.7e-80 267.6 0.0 5.9e-80 267.2 0.0 1.1 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 ETO17945.1 - 1.8e-10 40.6 0.0 2.4e-09 37.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.18 ETO17945.1 - 7.3e-09 34.8 0.0 1.5e-08 33.8 0.0 1.7 1 1 0 1 1 1 1 MCM2/3/5 family Mg_chelatase_2 PF13335.1 ETO17945.1 - 4.1e-07 30.2 0.0 7.1e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 ETO17945.1 - 4.7e-07 29.4 0.0 1.1e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA PF00004.24 ETO17945.1 - 0.00069 19.8 0.0 0.008 16.3 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETO17945.1 - 0.00079 19.5 0.0 0.11 12.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 ETO17945.1 - 0.0017 18.2 0.0 0.0032 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 ETO17945.1 - 0.0041 17.0 0.0 0.021 14.7 0.0 2.1 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 ETO17945.1 - 0.017 15.9 0.0 0.042 14.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 ETO17945.1 - 0.047 14.0 0.0 0.15 12.3 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 ETO17945.1 - 0.096 12.1 0.2 0.4 10.0 0.1 1.9 2 0 0 2 2 2 0 AAA-like domain RuvB_N PF05496.7 ETO17945.1 - 0.11 11.5 0.0 9 5.2 0.0 2.9 3 0 0 3 3 3 0 Holliday junction DNA helicase ruvB N-terminus ABC_tran PF00005.22 ETO17945.1 - 0.12 12.6 0.0 0.43 10.8 0.0 2.1 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.7 ETO17945.1 - 0.14 11.8 0.1 0.38 10.3 0.0 1.7 2 0 0 2 2 2 0 NACHT domain DUF721 PF05258.7 ETO17946.1 - 1.4e-12 47.6 0.0 4.1e-12 46.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF721) Dynein_light PF01221.13 ETO17946.1 - 0.18 11.8 0.7 2.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Dynein light chain type 1 Apis_Csd PF11671.3 ETO17947.1 - 0.11 12.3 6.4 0.19 11.5 4.4 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein Macoilin PF09726.4 ETO17947.1 - 0.3 9.3 7.7 0.37 9.0 5.4 1.1 1 0 0 1 1 1 0 Transmembrane protein TFIIA PF03153.8 ETO17947.1 - 0.34 10.7 9.9 0.44 10.3 6.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3367 PF11847.3 ETO17947.1 - 3.5 5.4 4.7 4.8 5.0 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) Secretin_N_2 PF07655.8 ETO17947.1 - 7.2 7.0 20.5 18 5.8 14.1 1.8 1 1 0 1 1 1 0 Secretin N-terminal domain Mit_proteolip PF08039.6 ETO17948.1 - 0.052 13.5 1.1 0.09 12.7 0.8 1.3 1 0 0 1 1 1 0 Mitochondrial proteolipid TFIIA PF03153.8 ETO17949.1 - 0.35 10.7 19.7 0.4 10.5 13.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dicty_REP PF05086.7 ETO17949.1 - 0.39 8.4 19.3 0.44 8.2 13.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 ETO17949.1 - 2.2 8.0 5.9 4 7.2 4.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF605 PF04652.11 ETO17949.1 - 3.1 7.0 17.6 4.1 6.7 12.2 1.2 1 0 0 1 1 1 0 Vta1 like DUF4551 PF15087.1 ETO17949.1 - 4.7 5.4 15.7 5.6 5.2 10.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF566 PF04484.7 ETO17949.1 - 7.1 6.0 18.3 9 5.7 12.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Transketolase_N PF00456.16 ETO17950.1 - 1.7e-107 359.1 0.0 1.9e-107 358.9 0.0 1.0 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.1 ETO17950.1 - 1.5e-08 33.9 0.2 4.8e-08 32.2 0.1 1.9 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 ETO17950.1 - 2.1e-05 24.1 0.0 3.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 ETO17950.1 - 0.0038 15.9 0.0 0.0048 15.6 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Terpene_synth PF01397.16 ETO17950.1 - 0.0062 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase, N-terminal domain eIF_4EBP PF05456.6 ETO17951.1 - 1.1 9.0 12.0 0.033 13.8 2.4 2.0 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) NOT2_3_5 PF04153.13 ETO17952.1 - 3.7e-22 78.6 5.9 3.7e-22 78.6 4.1 2.0 2 1 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Apis_Csd PF11671.3 ETO17952.1 - 4.6 7.0 19.1 2 8.2 10.8 2.0 2 0 0 2 2 2 0 Complementary sex determiner protein JSRP PF15312.1 ETO17953.1 - 5.8 6.9 6.7 0.67 9.9 0.1 2.8 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein LolB PF03550.9 ETO17954.1 - 0.067 12.7 0.1 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Outer membrane lipoprotein LolB DUF4203 PF13886.1 ETO17955.1 - 1.4e-09 37.7 16.6 2.2e-08 33.7 4.7 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4203) DUF3392 PF11872.3 ETO17955.1 - 0.012 15.5 0.6 0.012 15.5 0.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3392) DUF2668 PF10873.3 ETO17955.1 - 0.11 12.7 2.0 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2668) SNARE_assoc PF09335.6 ETO17955.1 - 0.11 12.6 0.5 0.11 12.6 0.3 3.4 3 1 1 4 4 4 0 SNARE associated Golgi protein FtsX PF02687.16 ETO17955.1 - 0.29 10.9 11.4 7.3 6.3 0.1 2.9 2 1 0 2 2 2 0 FtsX-like permease family C1_2 PF03107.11 ETO17956.1 - 0.00029 20.8 3.8 0.00081 19.4 2.6 1.8 1 0 0 1 1 1 1 C1 domain SAM_1 PF00536.25 ETO17956.1 - 0.0035 17.4 0.4 0.011 15.9 0.3 1.8 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 ETO17956.1 - 0.046 13.4 0.1 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain SAM_2 PF07647.12 ETO17956.1 - 0.05 13.4 0.3 0.21 11.4 0.2 2.0 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) Kelch_6 PF13964.1 ETO17957.1 - 1.5e-13 50.2 5.5 1.9e-05 24.6 0.5 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO17957.1 - 2.8e-07 29.9 4.0 0.0044 16.5 0.2 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO17957.1 - 0.00034 20.6 0.9 0.041 14.0 0.0 3.9 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO17957.1 - 0.0009 18.9 3.0 2 8.3 0.0 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETO17957.1 - 0.0043 16.7 3.4 0.58 9.9 0.0 4.3 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO17957.1 - 0.01 15.8 2.2 0.07 13.1 0.3 3.0 4 0 0 4 4 4 1 Kelch motif REJ PF02010.10 ETO17958.1 - 5.6e-15 54.5 5.3 2.1e-13 49.3 3.6 2.5 1 1 0 1 1 1 1 REJ domain His_kinase PF06580.8 ETO17959.1 - 0.09 12.7 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase Terminase_5 PF06056.7 ETO17959.1 - 0.11 12.1 0.3 6.7 6.3 0.1 2.3 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) Trypan_PARP PF05887.6 ETO17960.1 - 2.7 7.7 6.5 1.4 8.7 2.7 1.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Actin PF00022.14 ETO17961.1 - 2.4e-48 164.5 0.0 2.6e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 Actin DUF2114 PF09887.4 ETO17961.1 - 0.059 11.6 0.0 0.063 11.6 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) TPR_12 PF13424.1 ETO17962.1 - 8.8e-39 131.3 5.3 4.5e-15 55.3 0.1 4.3 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO17962.1 - 1.8e-24 85.1 18.8 1.6e-10 40.4 0.2 5.0 3 1 2 5 5 5 4 TPR repeat TPR_1 PF00515.23 ETO17962.1 - 1.2e-21 75.3 26.8 2e-07 30.2 0.6 7.4 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETO17962.1 - 1.3e-20 72.6 0.2 1.3e-08 34.4 0.0 5.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO17962.1 - 2.4e-19 67.6 24.3 5.5e-06 25.7 1.6 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.1 ETO17962.1 - 1.3e-17 62.1 5.5 3.7e-05 23.1 0.0 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO17962.1 - 1.1e-15 56.2 25.2 3.1e-06 26.6 0.1 7.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO17962.1 - 9.1e-11 41.0 5.4 0.016 15.3 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO17962.1 - 7.1e-10 39.2 0.1 0.0023 18.5 0.0 3.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO17962.1 - 9.1e-07 28.9 0.0 0.72 10.6 0.0 5.5 5 1 1 6 6 6 1 Tetratricopeptide repeat MIT PF04212.13 ETO17962.1 - 2.1e-06 27.4 10.7 0.011 15.6 0.1 4.7 3 2 1 4 4 4 2 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 ETO17962.1 - 2.9e-06 27.3 7.2 1 9.9 0.0 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO17962.1 - 4.6e-05 23.4 6.2 0.033 14.3 0.1 3.6 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 ETO17962.1 - 0.005 16.0 0.0 12 5.2 0.0 3.7 3 0 0 3 3 3 0 SHNi-TPR TPR_19 PF14559.1 ETO17962.1 - 0.0062 16.8 0.0 1.8 8.9 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_3 PF07720.7 ETO17962.1 - 0.089 12.6 9.5 0.14 12.0 0.3 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.15 ETO17962.1 - 0.097 12.6 2.8 1.4 9.0 0.0 3.6 4 0 0 4 4 3 0 PPR repeat Thioredoxin_8 PF13905.1 ETO17962.1 - 0.3 11.2 4.4 0.22 11.6 0.8 2.3 2 0 0 2 2 2 0 Thioredoxin-like Sel1 PF08238.7 ETO17962.1 - 7.8 7.2 8.4 15 6.3 0.1 3.9 4 0 0 4 4 3 0 Sel1 repeat NAAA-beta PF15508.1 ETO17964.1 - 0.012 15.9 3.3 13 6.1 0.0 3.7 2 2 1 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Baculo_PEP_C PF04513.7 ETO17964.1 - 0.3 10.8 3.3 10 5.9 0.0 3.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ArsC PF03960.10 ETO17964.1 - 0.93 9.5 6.9 1.9 8.5 0.1 3.1 3 0 0 3 3 3 0 ArsC family NAP PF00956.13 ETO17965.1 - 0.019 14.0 1.2 0.03 13.4 0.7 1.5 1 1 0 1 1 1 0 Nucleosome assembly protein (NAP) MutS_III PF05192.13 ETO17965.1 - 0.072 12.8 0.9 0.09 12.5 0.6 1.1 1 0 0 1 1 1 0 MutS domain III NodZ PF05830.6 ETO17966.1 - 1.5e-08 33.5 0.6 1.3e-06 27.2 0.0 2.8 3 0 0 3 3 3 2 Nodulation protein Z (NodZ) LIM_bind PF01803.11 ETO17967.1 - 4.6 6.2 12.6 0.16 11.0 2.9 2.5 2 0 0 2 2 2 0 LIM-domain binding protein RNase_H2-Ydr279 PF09468.5 ETO17967.1 - 5 6.2 22.7 0.018 14.2 4.9 3.1 3 0 0 3 3 3 0 Ydr279p protein family (RNase H2 complex component) Pro_isomerase PF00160.16 ETO17968.1 - 9.2e-45 152.6 0.2 1e-44 152.4 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SBDS_C PF09377.5 ETO17968.1 - 0.033 13.9 0.1 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 SBDS protein C-terminal domain DUF563 PF04577.9 ETO17969.1 - 0.00022 21.1 0.0 0.0005 20.0 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF563) DUF2967 PF11179.3 ETO17972.1 - 0.5 9.8 4.1 0.81 9.1 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) NUDIX_2 PF13869.1 ETO17972.1 - 0.63 9.3 7.4 0.76 9.0 4.2 1.8 1 1 0 1 1 1 0 Nucleotide hydrolase KIAA1430 PF13879.1 ETO17972.1 - 6.7 7.2 32.1 0.19 12.1 6.2 3.6 1 1 2 3 3 3 0 KIAA1430 homologue Metallophos PF00149.23 ETO17973.1 - 0.015 14.6 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Ycf1 PF05758.7 ETO17974.1 - 0.12 10.0 11.9 0.13 10.0 8.2 1.0 1 0 0 1 1 1 0 Ycf1 DUF4407 PF14362.1 ETO17974.1 - 0.47 9.3 14.0 0.59 9.0 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mem_trans PF03547.13 ETO17974.1 - 1.1 7.5 4.3 1.5 7.0 3.1 1.3 1 1 0 1 1 1 0 Membrane transport protein Presenilin PF01080.12 ETO17974.1 - 1.6 7.5 5.8 2 7.1 4.0 1.1 1 0 0 1 1 1 0 Presenilin RNA_pol_Rpb2_4 PF04566.8 ETO17975.1 - 1.7e-16 59.7 0.0 4.3e-16 58.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_2 PF04561.9 ETO17975.1 - 1.4e-09 37.6 0.1 0.0007 19.0 0.0 2.5 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_5 PF04567.12 ETO17975.1 - 1.9e-06 27.6 0.2 5.6e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 ETO17975.1 - 0.00011 21.8 0.0 0.00042 20.0 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_1 PF04563.10 ETO17975.1 - 0.0091 14.9 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit CDK2AP PF09806.4 ETO17975.1 - 0.01 16.0 2.9 0.016 15.4 2.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein SR-25 PF10500.4 ETO17975.1 - 0.032 13.7 17.3 0.072 12.5 12.0 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_capsid PF06112.6 ETO17975.1 - 0.13 12.3 10.0 0.22 11.5 6.9 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Macoilin PF09726.4 ETO17975.1 - 1.5 7.0 7.3 2.1 6.5 5.0 1.1 1 0 0 1 1 1 0 Transmembrane protein CAF-1_p150 PF11600.3 ETO17975.1 - 6.8 5.9 7.4 11 5.3 5.1 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF515 PF04415.7 ETO17975.1 - 7.3 4.7 13.1 11 4.0 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Copine PF07002.11 ETO17976.1 - 4.5e-35 120.5 2.4 1.1e-34 119.3 0.2 2.1 2 0 0 2 2 2 1 Copine vWA-TerF-like PF10138.4 ETO17976.1 - 1.3e-10 41.4 0.1 2e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.23 ETO17976.1 - 0.0021 17.7 0.1 0.0034 17.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF162 PF02589.10 ETO17976.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised ACR, YkgG family COG1556 Synapsin_C PF02750.9 ETO17977.1 - 4.1e-40 137.0 0.0 4.9e-40 136.8 0.0 1.1 1 0 0 1 1 1 1 Synapsin, ATP binding domain UPF0172 PF03665.8 ETO17978.1 - 0.0044 16.5 0.7 0.0054 16.2 0.5 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) DNA_pol_B_2 PF03175.8 ETO17978.1 - 0.0056 15.4 4.9 0.0064 15.2 3.4 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral NUFIP1 PF10453.4 ETO17978.1 - 8.6 5.9 9.0 1.4 8.4 1.9 2.4 2 0 0 2 2 2 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) GPS PF01825.16 ETO17979.1 - 0.00021 21.3 1.1 0.00021 21.3 0.7 2.4 2 0 0 2 2 2 1 Latrophilin/CL-1-like GPS domain Pkinase_Tyr PF07714.12 ETO17980.1 - 3.4e-46 157.4 0.0 7.4e-42 143.1 0.0 2.5 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 ETO17980.1 - 5.6e-40 137.1 2.6 1.1e-39 136.2 0.0 2.6 2 2 1 3 3 3 1 Protein kinase domain UN_NPL4 PF11543.3 ETO17980.1 - 0.02 15.1 2.3 0.15 12.3 1.6 2.3 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 Zip PF02535.17 ETO17980.1 - 0.055 12.4 4.1 0.093 11.7 2.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SR-25 PF10500.4 ETO17982.1 - 0.00027 20.4 8.4 0.00027 20.4 5.8 3.3 3 1 1 4 4 4 2 Nuclear RNA-splicing-associated protein DUF1615 PF07759.7 ETO17983.1 - 0.022 13.5 0.4 0.028 13.1 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1615) Daxx PF03344.10 ETO17983.1 - 0.035 12.6 0.1 0.045 12.2 0.1 1.1 1 0 0 1 1 1 0 Daxx Family TFIIA PF03153.8 ETO17984.1 - 2.3e-15 57.4 12.4 4.1e-15 56.5 8.6 1.4 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Ribosomal_L6e PF01159.14 ETO17984.1 - 0.85 9.8 6.6 1.6 8.9 4.5 1.6 1 0 0 1 1 1 0 Ribosomal protein L6e BTV_NS2 PF04514.7 ETO17984.1 - 1.5 7.6 13.1 1.8 7.3 9.1 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Trypan_PARP PF05887.6 ETO17985.1 - 0.018 14.8 9.7 0.036 13.8 6.7 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Abhydrolase_5 PF12695.2 ETO17986.1 - 3e-05 23.8 0.0 3.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETO17986.1 - 0.00064 19.6 0.0 0.00069 19.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 ETO17986.1 - 0.00072 19.4 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 ETO17986.1 - 0.014 14.9 0.0 0.017 14.6 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETO17986.1 - 0.12 11.5 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 ETO17986.1 - 0.14 11.5 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) ADK_lid PF05191.9 ETO17987.1 - 0.03 13.9 0.1 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 Adenylate kinase, active site lid OST-HTH PF12872.2 ETO17988.1 - 0.042 13.7 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 OST-HTH/LOTUS domain Pkinase PF00069.20 ETO17989.1 - 7.1e-09 35.1 0.3 1.6e-07 30.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO17989.1 - 0.0023 17.0 0.0 0.005 15.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase DDE_3 PF13358.1 ETO17990.1 - 8.3e-06 25.6 0.9 2.2e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF1971 PF09313.6 ETO17990.1 - 0.017 14.8 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) HHH_3 PF12836.2 ETO17990.1 - 0.12 12.3 0.2 0.12 12.3 0.1 1.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF1054 PF06335.7 ETO17991.1 - 0.0083 15.8 0.9 0.013 15.1 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1054) DUF3206 PF11472.3 ETO17991.1 - 0.17 11.6 3.3 0.27 11.0 1.8 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3206) 4HB_MCP_1 PF12729.2 ETO17991.1 - 0.21 10.9 10.9 1 8.6 7.5 2.0 1 1 0 1 1 1 0 Four helix bundle sensory module for signal transduction Syntaxin PF00804.20 ETO17991.1 - 0.42 10.7 8.1 0.8 9.9 1.8 2.2 1 1 1 2 2 2 0 Syntaxin FbpA PF05833.6 ETO17991.1 - 1.7 7.1 10.8 1.6 7.2 3.5 2.0 1 1 1 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) DHFR_1 PF00186.14 ETO17992.1 - 8.2e-33 113.2 0.0 1.1e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 Dihydrofolate reductase DUF1749 PF08538.5 ETO17992.1 - 0.073 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Thymidylat_synt PF00303.14 ETO17993.1 - 2.5e-80 269.3 1.5 9.7e-75 251.0 0.3 2.4 1 1 1 2 2 2 2 Thymidylate synthase PDZ_2 PF13180.1 ETO17994.1 - 0.001 18.9 0.6 0.34 10.8 0.0 2.7 3 0 0 3 3 3 2 PDZ domain HutD PF05962.6 ETO17994.1 - 0.056 13.1 0.0 0.15 11.7 0.0 1.6 1 1 0 1 1 1 0 HutD PDZ_2 PF13180.1 ETO17995.1 - 0.0028 17.4 0.0 0.0064 16.3 0.0 1.6 2 0 0 2 2 2 1 PDZ domain Trypsin_2 PF13365.1 ETO17996.1 - 0.0011 18.9 0.0 0.0013 18.7 0.0 1.1 1 0 0 1 1 1 1 Trypsin-like peptidase domain RepA_C PF04796.7 ETO17997.1 - 0.7 9.4 0.1 0.7 9.4 0.0 2.0 2 0 0 2 2 2 0 Plasmid encoded RepA protein Bap31 PF05529.7 ETO17997.1 - 4.8 6.5 7.1 7.7 5.9 4.9 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like TT_ORF1 PF02956.9 ETO17997.1 - 6.4 5.0 13.2 6.7 5.0 9.2 1.0 1 0 0 1 1 1 0 TT viral orf 1 Cys_knot PF00007.17 ETO18000.1 - 0.013 15.6 1.2 0.015 15.3 0.8 1.1 1 0 0 1 1 1 0 Cystine-knot domain DUF1644 PF07800.7 ETO18000.1 - 0.036 13.9 1.4 0.06 13.2 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) NAD_binding_7 PF13241.1 ETO18000.1 - 0.12 12.6 0.3 0.13 12.4 0.2 1.2 1 0 0 1 1 1 0 Putative NAD(P)-binding RNA_pol_Rpc4 PF05132.9 ETO18001.1 - 7.6e-08 32.4 19.9 1.5e-07 31.4 0.1 4.2 2 1 2 4 4 4 3 RNA polymerase III RPC4 MIP-T3 PF10243.4 ETO18002.1 - 0.0011 17.5 1.8 0.0011 17.5 1.2 3.2 3 0 0 3 3 3 1 Microtubule-binding protein MIP-T3 UCH PF00443.24 ETO18003.1 - 4.5e-31 107.9 5.3 5.2e-30 104.4 3.7 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO18003.1 - 1.9e-11 43.9 0.5 2.2e-09 37.1 0.0 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RXT2_N PF08595.6 ETO18003.1 - 1.2 8.9 14.4 0.46 10.2 7.0 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal Tom22 PF04281.8 ETO18003.1 - 2.2 7.8 5.9 4.9 6.6 3.3 2.1 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Sigma70_ner PF04546.8 ETO18003.1 - 5.1 6.6 12.8 1.4 8.4 6.3 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region Pox_Ag35 PF03286.9 ETO18003.1 - 5.4 6.4 15.2 0.11 12.0 4.5 2.2 2 1 0 2 2 2 0 Pox virus Ag35 surface protein UCH PF00443.24 ETO18004.1 - 1e-15 57.5 0.0 1.1e-15 57.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO18004.1 - 0.0049 16.3 0.0 0.0057 16.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_S27e PF01667.12 ETO18004.1 - 0.14 11.6 0.1 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S27 UCH PF00443.24 ETO18005.1 - 7.6e-20 71.1 0.0 1.2e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 ETO18006.1 - 1.1e-19 70.6 0.7 1.8e-19 69.8 0.4 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO18006.1 - 1.1e-09 38.2 1.4 1.1e-09 38.2 1.0 1.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Spc97_Spc98 PF04130.8 ETO18007.1 - 2.4e-21 75.6 6.1 3.1e-21 75.3 4.2 1.0 1 0 0 1 1 1 1 Spc97 / Spc98 family MIF4G_like PF09088.6 ETO18009.1 - 5.4e-26 91.1 2.2 1.1e-25 90.1 1.5 1.5 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 ETO18009.1 - 7.6e-11 41.8 7.3 1.7e-08 34.1 0.6 3.3 3 0 0 3 3 3 3 MIF4G domain PBP_sp32 PF07222.7 ETO18011.1 - 0.0064 15.7 3.1 0.011 14.9 2.1 1.3 1 0 0 1 1 1 1 Proacrosin binding protein sp32 DUF3774 PF12609.3 ETO18011.1 - 9.3 7.1 7.3 1.8 9.4 0.2 2.4 2 0 0 2 2 2 0 Wound-induced protein Ras PF00071.17 ETO18012.1 - 7.6e-37 126.1 0.2 7.1e-22 77.5 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 ETO18012.1 - 1.7e-13 51.0 0.2 4.6e-12 46.4 0.0 2.4 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO18012.1 - 2.7e-11 43.0 0.1 4.9e-07 29.1 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family PduV-EutP PF10662.4 ETO18012.1 - 0.00024 20.5 0.1 0.049 13.1 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 ETO18012.1 - 0.0026 16.9 0.5 0.0099 15.0 0.3 1.9 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 ETO18012.1 - 0.014 14.1 0.4 0.071 11.7 0.0 2.1 1 1 0 2 2 2 0 G-protein alpha subunit AAA_14 PF13173.1 ETO18012.1 - 0.035 14.0 0.2 0.11 12.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain CTNNB1_binding PF08347.6 ETO18013.1 - 0.26 11.5 2.1 0.39 10.9 1.4 1.5 1 1 0 1 1 1 0 N-terminal CTNNB1 binding Tctex-1 PF03645.8 ETO18014.1 - 3e-06 27.0 0.2 3e-06 27.0 0.1 1.9 2 1 1 3 3 3 1 Tctex-1 family Mem_trans PF03547.13 ETO18014.1 - 0.25 9.5 1.1 0.29 9.3 0.7 1.2 1 0 0 1 1 1 0 Membrane transport protein DUF4119 PF13494.1 ETO18015.1 - 1.2 9.1 7.0 1.9 8.5 2.5 2.7 3 0 0 3 3 3 0 Domain of unknown function, B. Theta Gene description (DUF4119) DUF3963 PF13124.1 ETO18016.1 - 2.9 7.7 4.6 24 4.8 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3963) RCC1 PF00415.13 ETO18017.1 - 0.00042 20.4 0.0 0.00081 19.5 0.0 1.5 1 0 0 1 1 1 1 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO18017.1 - 0.026 14.1 2.7 0.65 9.6 0.0 3.1 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO18018.1 - 8.1e-17 60.3 3.0 1.1e-06 28.0 0.1 3.3 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 ETO18018.1 - 3.3e-14 52.8 0.2 0.0047 17.0 0.1 5.2 4 1 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat Renin_r PF07850.9 ETO18020.1 - 0.046 14.0 0.7 0.14 12.5 0.0 2.1 2 1 0 2 2 2 0 Renin receptor-like protein LKAAEAR PF15478.1 ETO18020.1 - 0.21 11.8 5.8 0.43 10.8 3.6 1.8 1 1 0 1 1 1 0 Family of unknown function with LKAAEAR motif RNR_N PF08343.5 ETO18020.1 - 0.64 9.8 4.4 11 5.8 0.9 2.4 2 0 0 2 2 2 0 Ribonucleotide reductase N-terminal zf-UBP PF02148.14 ETO18021.1 - 4.5e-14 52.2 7.5 4.5e-14 52.2 5.2 1.8 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein BRAP2 PF07576.7 ETO18022.1 - 8.2e-05 22.1 0.1 8.2e-05 22.1 0.1 2.2 2 0 0 2 2 2 1 BRCA1-associated protein 2 Adaptin_binding PF10199.4 ETO18022.1 - 0.098 12.9 11.6 0.74 10.0 4.1 2.4 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Methyltransf_12 PF08242.7 ETO18022.1 - 0.17 12.3 7.1 0.82 10.1 1.5 2.5 2 0 0 2 2 2 0 Methyltransferase domain Secretin_N_2 PF07655.8 ETO18022.1 - 1.2 9.5 32.0 0.66 10.3 8.9 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain Neur_chan_memb PF02932.11 ETO18022.1 - 1.3 8.9 15.1 0.19 11.5 1.1 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Tom22 PF04281.8 ETO18022.1 - 3.3 7.2 7.6 0.37 10.3 1.8 1.9 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 TetR_N PF00440.18 ETO18023.1 - 4.1e-16 58.3 0.1 9.2e-16 57.2 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family GSP_synth PF03738.9 ETO18023.1 - 0.014 15.6 0.0 0.053 13.7 0.0 2.0 2 0 0 2 2 2 0 Glutathionylspermidine synthase preATP-grasp HTH_7 PF02796.10 ETO18023.1 - 0.024 14.5 0.0 4 7.3 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_24 PF13412.1 ETO18023.1 - 0.038 13.3 0.0 2.2 7.7 0.0 2.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF3930 PF13067.1 ETO18024.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3930) STAT_alpha PF01017.15 ETO18024.1 - 0.019 14.6 7.3 0.053 13.2 5.1 1.7 1 1 0 1 1 1 0 STAT protein, all-alpha domain XhlA PF10779.4 ETO18024.1 - 0.025 14.4 16.6 1.3 8.9 9.0 2.2 2 0 0 2 2 2 0 Haemolysin XhlA NAS PF03059.11 ETO18024.1 - 0.045 12.9 0.9 0.053 12.6 0.6 1.1 1 0 0 1 1 1 0 Nicotianamine synthase protein CorA PF01544.13 ETO18024.1 - 0.055 12.4 2.2 0.077 12.0 1.5 1.3 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Reo_sigmaC PF04582.7 ETO18024.1 - 0.086 12.0 1.9 0.12 11.5 1.3 1.3 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF4201 PF13870.1 ETO18024.1 - 0.094 12.1 12.8 2.3 7.5 6.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) TPR_MLP1_2 PF07926.7 ETO18024.1 - 0.096 12.4 16.3 0.19 11.5 7.5 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Mga PF05043.8 ETO18024.1 - 0.19 11.9 3.1 0.35 11.1 0.9 2.2 1 1 1 2 2 2 0 Mga helix-turn-helix domain Spc7 PF08317.6 ETO18024.1 - 0.21 10.1 13.9 0.25 9.9 9.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4404 PF14357.1 ETO18024.1 - 0.22 11.9 11.6 0.77 10.2 5.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) WXG100 PF06013.7 ETO18024.1 - 0.28 11.1 2.0 1 9.4 0.1 2.3 1 1 0 2 2 2 0 Proteins of 100 residues with WXG Sec8_exocyst PF04048.9 ETO18024.1 - 0.36 10.4 9.8 0.87 9.2 2.6 2.4 1 1 0 2 2 2 0 Sec8 exocyst complex component specific domain Cep57_CLD_2 PF14197.1 ETO18024.1 - 0.43 10.5 9.9 0.22 11.5 4.1 2.1 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 AAA_13 PF13166.1 ETO18024.1 - 0.44 8.9 11.6 0.48 8.8 8.0 1.1 1 0 0 1 1 1 0 AAA domain Prefoldin PF02996.12 ETO18024.1 - 0.61 9.7 14.5 2e+02 1.5 9.1 2.6 1 1 1 2 2 2 0 Prefoldin subunit DUF745 PF05335.8 ETO18024.1 - 0.9 9.0 8.3 3.6 7.0 2.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Baculo_PEP_C PF04513.7 ETO18024.1 - 0.98 9.2 5.0 9.1 6.1 0.1 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Striatin PF08232.7 ETO18024.1 - 1.2 9.4 11.9 4.8 7.5 8.3 1.8 1 1 0 1 1 1 0 Striatin family L31 PF09784.4 ETO18024.1 - 1.3 9.1 7.7 9.8 6.3 2.2 2.2 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L31 Fib_alpha PF08702.5 ETO18024.1 - 1.3 9.1 12.1 42 4.2 8.4 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4200 PF13863.1 ETO18024.1 - 1.3 8.9 16.9 2.9 7.8 9.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF848 PF05852.6 ETO18024.1 - 1.4 8.7 14.2 1 9.2 7.0 2.0 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Syntaxin_2 PF14523.1 ETO18024.1 - 1.7 8.7 10.0 6.8 6.7 6.8 1.9 1 1 0 1 1 1 0 Syntaxin-like protein ATP-synt_E PF05680.7 ETO18024.1 - 1.8 8.5 8.4 0.18 11.7 2.6 1.8 2 0 0 2 2 2 0 ATP synthase E chain Phage_GP20 PF06810.6 ETO18024.1 - 2 7.8 15.6 0.81 9.1 7.4 2.0 2 0 0 2 2 2 0 Phage minor structural protein GP20 DUF2681 PF10883.3 ETO18024.1 - 2.8 8.2 9.0 0.36 11.0 3.6 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF2681) Cauli_AT PF03233.8 ETO18024.1 - 3 7.5 9.9 2.8 7.6 5.3 1.7 1 1 1 2 2 2 0 Aphid transmission protein DUF3552 PF12072.3 ETO18024.1 - 3.1 6.9 16.9 2 7.5 8.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Nop25 PF09805.4 ETO18024.1 - 3.8 7.5 15.4 2.3 8.2 6.8 2.0 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) HemX PF04375.9 ETO18024.1 - 4 5.9 8.2 2 6.9 4.2 1.5 1 1 0 1 1 1 0 HemX DivIC PF04977.10 ETO18024.1 - 4 6.9 17.7 6.7 6.2 4.8 3.1 2 1 1 3 3 3 0 Septum formation initiator AAA_23 PF13476.1 ETO18024.1 - 4.6 7.5 13.3 5.1 7.3 9.2 1.1 1 0 0 1 1 1 0 AAA domain DUF2951 PF11166.3 ETO18024.1 - 5.4 6.9 14.0 3 7.7 2.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) TMF_DNA_bd PF12329.3 ETO18024.1 - 5.7 6.8 22.5 12 5.8 0.3 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Seryl_tRNA_N PF02403.17 ETO18024.1 - 6.7 6.7 18.5 15 5.6 9.5 2.1 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.7 ETO18024.1 - 7 6.4 13.0 2 8.2 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4463 PF14703.1 ETO18024.1 - 8.3 7.0 8.2 4 8.0 3.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) V_ATPase_I PF01496.14 ETO18024.1 - 8.6 4.0 9.7 10 3.8 6.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TPR_16 PF13432.1 ETO18025.1 - 1.4e-13 51.1 0.0 0.0018 18.9 0.0 4.2 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO18025.1 - 2.9e-13 49.2 3.3 0.0017 17.9 0.0 3.6 3 1 0 3 3 3 3 TPR repeat TPR_2 PF07719.12 ETO18025.1 - 1.8e-12 46.1 9.7 0.028 14.3 0.1 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 ETO18025.1 - 3.4e-10 39.6 2.7 1.7e-07 31.0 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO18025.1 - 6.8e-08 32.3 9.2 0.002 18.0 0.0 4.2 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO18025.1 - 2.6e-07 29.9 15.5 0.2 11.3 0.1 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO18025.1 - 3.6e-07 30.4 4.4 0.0041 17.4 0.0 3.9 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO18025.1 - 5.3e-07 28.9 7.6 2.1 8.3 0.0 6.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO18025.1 - 6.8e-07 29.0 2.1 0.35 11.1 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO18025.1 - 3.9e-06 26.9 0.3 0.47 11.2 0.3 5.3 3 2 3 6 6 6 1 Tetratricopeptide repeat Paf67 PF10255.4 ETO18025.1 - 0.0018 17.2 0.5 0.0075 15.1 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase I-associated factor PAF67 Apc3 PF12895.2 ETO18025.1 - 0.0019 18.2 8.5 0.14 12.3 0.0 3.7 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 ETO18025.1 - 0.015 15.0 3.0 13 5.8 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat YfiO PF13525.1 ETO18025.1 - 0.08 12.3 0.1 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 Outer membrane lipoprotein Fis1_TPR_C PF14853.1 ETO18025.1 - 0.096 12.5 7.1 3.7 7.5 0.2 5.1 5 2 2 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat Lzipper-MIP1 PF14389.1 ETO18029.1 - 0.013 15.5 8.9 0.013 15.5 6.1 1.8 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Phage_gp53 PF11246.3 ETO18029.1 - 0.037 13.4 0.2 0.052 12.9 0.1 1.2 1 0 0 1 1 1 0 Base plate wedge protein 53 Imm48 PF15587.1 ETO18029.1 - 0.07 12.5 1.2 0.12 11.6 0.8 1.7 1 1 0 1 1 1 0 Immunity protein 48 XRCC4 PF06632.7 ETO18029.1 - 0.072 11.9 7.2 0.083 11.7 5.0 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF4207 PF13904.1 ETO18029.1 - 0.12 11.7 10.4 0.16 11.3 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Baculo_PEP_C PF04513.7 ETO18029.1 - 0.19 11.5 4.5 0.33 10.7 3.1 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_C11 PF03415.9 ETO18029.1 - 0.27 10.1 2.0 0.53 9.2 1.4 1.5 1 1 1 2 2 2 0 Clostripain family DUF3086 PF11285.3 ETO18029.1 - 0.28 9.9 8.3 0.12 11.1 3.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3086) Ubiquitin_2 PF14560.1 ETO18029.1 - 0.42 10.8 2.2 0.67 10.2 1.2 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain Occludin_ELL PF07303.8 ETO18029.1 - 0.59 10.8 9.3 2.2 9.0 2.5 2.1 1 1 1 2 2 2 0 Occludin homology domain YPEB PF14620.1 ETO18029.1 - 1 8.3 13.5 1.3 7.9 7.4 1.8 1 1 1 2 2 2 0 YpeB sporulation DUF342 PF03961.8 ETO18029.1 - 1.1 7.6 10.0 1.2 7.4 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) WHEP-TRS PF00458.15 ETO18029.1 - 1.1 8.9 7.5 0.46 10.1 2.5 2.1 2 0 0 2 2 2 0 WHEP-TRS domain COG2 PF06148.6 ETO18029.1 - 1.1 9.0 6.6 5.5 6.8 3.2 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3347 PF11827.3 ETO18029.1 - 2.1 8.2 7.8 2.5 8.0 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Allexi_40kDa PF05549.6 ETO18029.1 - 2.5 7.2 6.5 7.4 5.7 4.5 1.7 1 1 0 1 1 1 0 Allexivirus 40kDa protein Complex1_LYR_2 PF13233.1 ETO18029.1 - 2.6 8.5 8.1 1.7 9.1 3.3 2.0 1 1 1 2 2 2 0 Complex1_LYR-like 5_nucleotid PF05761.9 ETO18029.1 - 2.9 6.3 7.6 1 7.8 3.5 1.5 1 1 1 2 2 2 0 5' nucleotidase family Activator_LAG-3 PF11498.3 ETO18029.1 - 3.9 6.1 13.4 4.3 5.9 9.3 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 APG6 PF04111.7 ETO18029.1 - 6.4 5.7 13.4 8.2 5.3 9.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 ETO18029.1 - 9.6 5.0 13.5 12 4.7 9.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Abhydrolase_5 PF12695.2 ETO18030.1 - 3.6e-16 59.2 0.0 5.8e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETO18030.1 - 1.3e-15 57.9 0.0 1.9e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETO18030.1 - 3.2e-05 23.7 0.2 6.5e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 ETO18030.1 - 0.00013 21.4 0.3 0.0088 15.4 0.1 2.9 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase PF00756.15 ETO18030.1 - 0.00056 19.4 0.0 0.00099 18.5 0.0 1.4 2 0 0 2 2 2 1 Putative esterase Abhydrolase_3 PF07859.8 ETO18030.1 - 0.015 14.8 0.0 0.048 13.2 0.0 1.9 3 0 0 3 3 3 0 alpha/beta hydrolase fold TLD PF07534.11 ETO18031.1 - 1.4e-17 64.0 1.9 2.1e-17 63.4 1.3 1.3 1 0 0 1 1 1 1 TLD CENP-P PF13096.1 ETO18031.1 - 0.033 13.4 0.0 0.061 12.6 0.0 1.4 1 0 0 1 1 1 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P fn3 PF00041.16 ETO18031.1 - 0.1 12.7 0.0 0.53 10.4 0.0 2.2 2 0 0 2 2 2 0 Fibronectin type III domain NARP1 PF12569.3 ETO18031.1 - 0.57 8.8 9.7 0.93 8.1 6.8 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Vfa1 PF08432.5 ETO18031.1 - 1.8 8.5 18.2 3.8 7.5 12.6 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1510 PF07423.6 ETO18031.1 - 3 7.1 15.7 5.1 6.4 10.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RP-C_C PF11800.3 ETO18031.1 - 3.8 7.1 5.7 6.3 6.4 4.0 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region PsbR PF04725.7 ETO18032.1 - 0.12 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Photosystem II 10 kDa polypeptide PsbR DUF4475 PF14753.1 ETO18033.1 - 0.0014 18.1 1.1 0.0017 17.8 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4475) Pex14_N PF04695.8 ETO18034.1 - 0.09 12.8 0.8 0.13 12.3 0.6 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF912 PF06024.7 ETO18034.1 - 3 7.9 14.4 5.3 7.1 10.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Secretin_N_2 PF07655.8 ETO18034.1 - 5.9 7.3 23.1 11 6.4 16.0 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain FAM176 PF14851.1 ETO18035.1 - 2.7 7.6 7.4 4.4 6.9 0.8 2.6 2 0 0 2 2 2 0 FAM176 family Thioredoxin_4 PF13462.1 ETO18037.1 - 0.066 13.2 2.4 0.47 10.4 0.5 2.2 1 1 1 2 2 2 0 Thioredoxin DUF2890 PF11081.3 ETO18038.1 - 0.011 15.8 3.1 0.011 15.8 2.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2890) Dsh_C PF12316.3 ETO18038.1 - 0.013 15.6 7.1 0.013 15.6 4.9 2.2 1 1 1 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal DAGK_cat PF00781.19 ETO18039.1 - 6.4e-05 22.4 0.0 0.00022 20.6 0.0 1.9 1 1 1 2 2 2 1 Diacylglycerol kinase catalytic domain dDENN PF03455.14 ETO18040.1 - 0.0073 16.3 5.5 0.53 10.3 0.2 3.3 4 0 0 4 4 4 2 dDENN domain Dicty_REP PF05086.7 ETO18040.1 - 3.6 5.2 7.9 4.9 4.7 5.5 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RRM_1 PF00076.17 ETO18041.1 - 0.0023 17.5 0.0 0.042 13.4 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETO18041.1 - 0.03 14.0 0.1 0.065 13.0 0.0 1.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_6 PF14259.1 ETO18041.1 - 0.033 14.1 0.0 0.068 13.1 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 ETO18043.1 - 1.7e-31 106.9 10.5 7.9e-07 28.7 0.0 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO18043.1 - 6 5.4 11.5 12 4.4 6.2 2.6 2 1 0 2 2 2 0 Nup133 N terminal like FAD_binding_4 PF01565.18 ETO18044.1 - 4e-06 26.3 0.0 8.2e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Copine PF07002.11 ETO18044.1 - 5.7e-05 22.8 1.9 0.0003 20.5 1.3 2.1 1 1 0 1 1 1 1 Copine RimM PF01782.13 ETO18044.1 - 0.11 12.3 0.1 0.4 10.6 0.0 1.9 2 0 0 2 2 2 0 RimM N-terminal domain Methyltrans_RNA PF04452.9 ETO18048.1 - 0.09 11.8 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 RNA methyltransferase Thioredoxin_6 PF13848.1 ETO18048.1 - 0.1 12.4 0.1 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain WD40 PF00400.27 ETO18049.1 - 8.6e-68 221.9 13.5 4.7e-13 48.4 0.0 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO18049.1 - 2.8e-18 65.3 11.2 1.5e-05 23.3 0.2 6.1 3 2 1 6 6 6 6 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO18049.1 - 0.0051 15.6 7.7 0.51 9.0 0.3 4.2 2 1 2 5 5 5 2 Nup133 N terminal like IncA PF04156.9 ETO18049.1 - 0.23 11.0 15.3 0.4 10.2 10.6 1.4 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 ETO18049.1 - 1.2 6.8 17.1 0.43 8.3 8.5 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF1975 PF09318.5 ETO18049.1 - 3.3 7.2 14.7 0.53 9.8 3.9 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF1975) TPR_MLP1_2 PF07926.7 ETO18049.1 - 4.4 7.0 19.9 8.2 6.1 13.8 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.16 ETO18049.1 - 9.1 6.3 11.3 0.45 10.5 2.3 2.5 2 1 0 2 2 2 0 bZIP transcription factor Ras PF00071.17 ETO18051.1 - 3.5e-54 182.5 0.8 4.3e-54 182.2 0.6 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.16 ETO18051.1 - 8e-20 70.7 0.1 9.8e-20 70.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 ETO18051.1 - 2.1e-18 66.9 0.0 5.3e-18 65.6 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 ETO18051.1 - 3.7e-10 39.3 0.1 4.9e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 ETO18051.1 - 1.8e-05 24.2 0.0 0.00015 21.2 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 ETO18051.1 - 0.00039 20.3 0.0 0.00057 19.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 ETO18051.1 - 0.0036 16.5 0.0 0.0053 16.0 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 ETO18051.1 - 0.0052 16.9 0.0 0.013 15.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 ETO18051.1 - 0.022 14.4 0.1 0.041 13.5 0.0 1.3 1 1 0 1 1 1 0 Archaeal ATPase AAA_16 PF13191.1 ETO18051.1 - 0.022 14.7 0.0 0.085 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_2 PF07724.9 ETO18051.1 - 0.024 14.5 0.1 3.7 7.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) DAP3 PF10236.4 ETO18051.1 - 0.071 12.0 0.0 0.96 8.3 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF258 PF03193.11 ETO18051.1 - 0.082 12.0 0.1 0.15 11.2 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 ETO18051.1 - 0.085 12.4 0.6 0.12 11.9 0.4 1.5 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 ETO18051.1 - 0.094 11.7 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Septin Kelch_1 PF01344.20 ETO18052.1 - 2.6e-06 26.8 2.2 0.076 12.5 0.1 4.1 4 1 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 ETO18052.1 - 1e-05 25.4 6.2 0.024 14.8 0.0 3.8 3 1 1 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO18052.1 - 0.0052 16.9 0.0 2.5 8.3 0.0 3.2 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO18052.1 - 0.013 15.2 0.6 2.4 8.0 0.0 2.9 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO18052.1 - 0.015 15.2 0.0 0.041 13.8 0.0 1.7 1 0 0 1 1 1 0 Kelch motif Kelch_2 PF07646.10 ETO18052.1 - 3.2 7.6 5.4 9.7 6.1 0.2 3.4 4 1 0 4 4 4 0 Kelch motif Pkinase PF00069.20 ETO18053.1 - 1.2e-10 40.9 0.2 1.2e-10 40.9 0.1 2.3 3 1 0 3 3 3 1 Protein kinase domain EF-hand_7 PF13499.1 ETO18053.1 - 0.004 17.2 0.9 0.024 14.7 0.2 2.4 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO18053.1 - 0.008 15.9 0.1 0.025 14.4 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.27 ETO18053.1 - 0.027 13.7 0.3 0.074 12.3 0.2 1.8 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.1 ETO18054.1 - 3.2e-11 43.2 4.0 4.1e-11 42.8 2.8 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO18054.1 - 4e-10 38.2 9.2 1.7e-07 30.0 1.3 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 ETO18054.1 - 1.1e-07 31.1 3.9 0.00092 18.9 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 ETO18054.1 - 6.8e-07 28.8 5.8 1.3e-06 27.9 3.4 1.8 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 ETO18054.1 - 2.2e-06 26.7 6.2 0.0028 16.9 0.4 2.3 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.2 ETO18054.1 - 3.9e-05 23.3 0.8 4.7e-05 23.0 0.5 1.2 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 ETO18054.1 - 0.0068 16.4 2.4 0.0083 16.1 1.7 1.2 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.13 ETO18054.1 - 0.0083 15.7 2.7 0.094 12.4 0.1 2.3 2 0 0 2 2 2 1 Dockerin type I repeat MgtE_N PF03448.12 ETO18054.1 - 0.058 13.7 0.2 0.077 13.3 0.1 1.3 1 0 0 1 1 1 0 MgtE intracellular N domain DUF3805 PF12712.2 ETO18055.1 - 0.043 13.6 0.2 0.073 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3805) EF-hand_1 PF00036.27 ETO18056.1 - 5.9e-29 97.1 20.5 5.7e-09 34.6 0.1 5.3 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 ETO18056.1 - 1.2e-25 89.4 13.1 1.1e-14 54.3 1.1 2.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 ETO18056.1 - 3.7e-25 87.2 13.8 2.9e-13 49.2 0.7 3.8 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 ETO18056.1 - 1.1e-24 84.0 17.2 6.5e-08 31.8 0.4 5.1 5 1 1 6 6 6 4 EF-hand domain EF-hand_5 PF13202.1 ETO18056.1 - 2.2e-21 74.1 25.3 1.7e-06 27.1 1.0 5.7 5 1 1 6 6 6 4 EF hand EF-hand_9 PF14658.1 ETO18056.1 - 4e-09 36.2 0.1 0.0013 18.6 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 ETO18056.1 - 1.3e-06 28.0 7.0 0.00076 19.1 0.2 3.2 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 ETO18056.1 - 0.00011 22.2 6.0 0.099 12.6 1.7 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF3349 PF11829.3 ETO18056.1 - 0.0037 17.6 0.0 2.9 8.3 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF3349) DUF1456 PF07308.8 ETO18056.1 - 0.094 12.7 1.7 3.8 7.6 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) Asp-B-Hydro_N PF05279.6 ETO18056.1 - 0.54 10.0 12.2 1.3 8.8 0.1 3.0 1 1 2 3 3 3 0 Aspartyl beta-hydroxylase N-terminal region NdhL PF10716.4 ETO18057.1 - 0.0085 15.8 1.8 0.016 14.9 1.3 1.4 1 0 0 1 1 1 1 NADH dehydrogenase transmembrane subunit DUF368 PF04018.8 ETO18057.1 - 0.11 11.6 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF368) NARP1 PF12569.3 ETO18057.1 - 1.7 7.3 21.3 0.11 11.1 4.2 2.4 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Vfa1 PF08432.5 ETO18057.1 - 6.3 6.7 33.4 1 9.3 6.7 2.7 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 ABC2_membrane_3 PF12698.2 ETO18057.1 - 8.8 5.2 12.9 0.25 10.3 1.3 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF4614 PF15391.1 ETO18057.1 - 9.3 5.9 17.3 0.33 10.7 3.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) SNF2_N PF00176.18 ETO18059.1 - 5.8e-26 90.9 0.0 1.2e-25 89.9 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 ETO18059.1 - 5.1e-06 26.4 0.0 2.2e-05 24.3 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 ETO18059.1 - 0.049 12.6 0.0 0.13 11.2 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Herpes_UL49_1 PF03117.9 ETO18060.1 - 0.014 14.4 0.3 0.023 13.8 0.2 1.3 1 1 0 1 1 1 0 UL49 family PQQ_3 PF13570.1 ETO18060.1 - 0.016 15.4 0.8 0.9 9.9 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain Nucleoporin_N PF08801.6 ETO18060.1 - 0.018 13.7 0.3 0.14 10.8 0.0 1.9 1 1 1 2 2 2 0 Nup133 N terminal like G-alpha PF00503.15 ETO18061.1 - 2.7e-30 105.3 6.1 3.3e-30 105.0 4.2 1.1 1 0 0 1 1 1 1 G-protein alpha subunit DUF3801 PF12687.2 ETO18061.1 - 0.021 14.4 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) Occludin_ELL PF07303.8 ETO18062.1 - 0.0039 17.9 4.8 0.0039 17.9 3.4 3.1 1 1 1 2 2 2 1 Occludin homology domain IBP39 PF11422.3 ETO18062.1 - 0.026 14.0 3.3 1.6 8.2 0.6 2.2 1 1 1 2 2 2 0 Initiator binding protein 39 kDa Med21 PF11221.3 ETO18062.1 - 0.051 13.5 1.2 0.051 13.5 0.8 3.1 2 1 1 3 3 3 0 Subunit 21 of Mediator complex Senescence PF06911.7 ETO18062.1 - 0.057 13.1 4.4 3.5 7.2 1.0 2.3 1 1 0 2 2 2 0 Senescence-associated protein DUF4201 PF13870.1 ETO18062.1 - 0.07 12.5 0.4 0.07 12.5 0.3 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) MAD PF05557.8 ETO18062.1 - 0.077 11.0 38.7 0.098 10.7 26.8 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein Cep57_CLD_2 PF14197.1 ETO18062.1 - 0.19 11.7 0.2 0.19 11.7 0.1 3.9 2 1 1 4 4 4 0 Centrosome localisation domain of PPC89 TPR_MLP1_2 PF07926.7 ETO18062.1 - 0.44 10.2 43.1 1.2 8.8 6.5 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 ETO18062.1 - 0.47 10.0 37.8 0.28 10.7 10.6 2.7 1 1 1 2 2 2 0 IncA protein Metal_resist PF13801.1 ETO18062.1 - 0.74 9.8 5.1 0.17 11.8 0.7 2.1 3 0 0 3 3 3 0 Heavy-metal resistance CENP-Q PF13094.1 ETO18062.1 - 0.76 9.7 38.7 0.84 9.6 9.5 2.7 1 1 2 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit AAA_13 PF13166.1 ETO18062.1 - 1.7 7.0 31.6 0.1 11.0 17.2 1.8 1 1 0 1 1 1 0 AAA domain AA_kinase PF00696.23 ETO18062.1 - 2 7.8 4.7 16 4.9 0.0 2.2 2 0 0 2 2 2 0 Amino acid kinase family DUF2937 PF11157.3 ETO18062.1 - 2.6 7.3 7.9 3.8 6.7 0.9 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF2937) Filament PF00038.16 ETO18062.1 - 3.7 6.9 36.0 3 7.2 10.8 2.5 1 1 1 2 2 2 0 Intermediate filament protein DivIVA PF05103.8 ETO18062.1 - 4 7.4 35.4 0.081 12.9 0.7 3.6 1 1 2 3 3 3 0 DivIVA protein CCDC155 PF14662.1 ETO18062.1 - 5.7 6.4 40.6 0.21 11.1 12.5 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Tropomyosin_1 PF12718.2 ETO18062.1 - 6.5 6.6 47.0 3 7.6 2.2 3.1 1 1 1 3 3 3 0 Tropomyosin like TMF_DNA_bd PF12329.3 ETO18062.1 - 7.6 6.4 52.3 0.12 12.2 2.5 4.7 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF148 PF02520.12 ETO18062.1 - 7.6 6.3 32.4 2 8.2 12.1 3.2 2 1 1 3 3 3 0 Domain of unknown function DUF148 Herpes_BLRF2 PF05812.7 ETO18063.1 - 0.00026 20.7 3.0 0.00026 20.7 2.1 3.1 1 1 1 2 2 2 1 Herpesvirus BLRF2 protein BLOC1_2 PF10046.4 ETO18063.1 - 0.00033 20.7 15.4 0.00053 20.0 6.0 2.6 2 1 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 ETO18063.1 - 0.0015 18.1 20.5 0.0057 16.2 8.0 2.0 1 1 1 2 2 2 1 IncA protein TSC22 PF01166.13 ETO18063.1 - 0.0024 17.7 0.5 0.0024 17.7 0.3 3.2 2 1 0 2 2 2 1 TSC-22/dip/bun family SlyX PF04102.7 ETO18063.1 - 0.0033 17.7 16.4 0.033 14.5 2.5 2.5 1 1 1 2 2 2 1 SlyX TPR_MLP1_2 PF07926.7 ETO18063.1 - 0.0035 17.0 18.9 0.0052 16.5 13.1 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.6 ETO18063.1 - 0.0038 17.0 15.7 0.16 11.9 1.0 3.2 3 0 0 3 3 3 1 Flagella accessory protein C (FlaC) CENP-Q PF13094.1 ETO18063.1 - 0.0076 16.2 18.6 0.029 14.3 4.0 2.2 1 1 1 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Reo_sigmaC PF04582.7 ETO18063.1 - 0.0096 15.1 5.7 0.012 14.8 4.0 1.0 1 0 0 1 1 1 1 Reovirus sigma C capsid protein HOOK PF05622.7 ETO18063.1 - 0.015 13.1 17.0 0.021 12.6 11.8 1.2 1 0 0 1 1 1 0 HOOK protein Myosin_tail_1 PF01576.14 ETO18063.1 - 0.016 12.9 16.1 0.024 12.4 11.2 1.2 1 0 0 1 1 1 0 Myosin tail TACC PF05010.9 ETO18063.1 - 0.02 14.6 17.7 0.028 14.2 12.3 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) DivIC PF04977.10 ETO18063.1 - 0.021 14.3 24.5 0.11 11.9 2.7 3.1 1 1 2 3 3 3 0 Septum formation initiator DUF3450 PF11932.3 ETO18063.1 - 0.03 13.6 17.4 0.066 12.4 4.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) CCDC155 PF14662.1 ETO18063.1 - 0.033 13.7 18.5 0.039 13.5 12.8 1.0 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 Cortex-I_coil PF09304.5 ETO18063.1 - 0.043 13.8 18.9 0.19 11.7 6.2 2.2 1 1 1 2 2 2 0 Cortexillin I, coiled coil Filament PF00038.16 ETO18063.1 - 0.049 13.1 16.8 1.5 8.2 11.7 2.0 1 1 0 1 1 1 0 Intermediate filament protein DUF3557 PF12078.3 ETO18063.1 - 0.055 13.1 2.1 0.073 12.7 1.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3557) DUF3584 PF12128.3 ETO18063.1 - 0.058 10.7 13.5 0.071 10.4 9.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1664 PF07889.7 ETO18063.1 - 0.059 13.1 10.7 0.75 9.6 5.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF869 PF05911.6 ETO18063.1 - 0.062 11.5 15.3 0.085 11.0 10.6 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) AAA_13 PF13166.1 ETO18063.1 - 0.064 11.7 15.5 0.045 12.2 1.8 2.0 1 1 1 2 2 2 0 AAA domain bZIP_1 PF00170.16 ETO18063.1 - 0.076 12.9 21.0 0.14 12.0 1.5 3.2 2 1 1 3 3 3 0 bZIP transcription factor Mnd1 PF03962.10 ETO18063.1 - 0.082 12.5 16.6 0.25 10.9 11.5 1.7 1 1 0 1 1 1 0 Mnd1 family Vps5 PF09325.5 ETO18063.1 - 0.087 12.0 14.0 0.12 11.6 3.5 2.1 1 1 1 2 2 2 0 Vps5 C terminal like WEMBL PF05701.6 ETO18063.1 - 0.087 11.2 15.5 0.11 10.9 10.7 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Colicin PF01024.14 ETO18063.1 - 0.1 12.1 2.4 0.12 11.9 1.7 1.2 1 0 0 1 1 1 0 Colicin pore forming domain CENP-F_leu_zip PF10473.4 ETO18063.1 - 0.11 12.3 23.0 1.7 8.4 1.9 2.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 THP2 PF09432.5 ETO18063.1 - 0.11 12.3 7.5 0.17 11.7 5.2 1.3 1 0 0 1 1 1 0 Tho complex subunit THP2 GAS PF13851.1 ETO18063.1 - 0.13 11.4 20.5 0.033 13.3 10.1 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Bap31 PF05529.7 ETO18063.1 - 0.14 11.6 18.2 1.1e+02 2.2 12.6 2.1 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF904 PF06005.7 ETO18063.1 - 0.17 12.2 25.1 1.5e+04 -5.0 17.4 2.8 1 1 0 1 1 0 0 Protein of unknown function (DUF904) DUF4164 PF13747.1 ETO18063.1 - 0.17 12.0 15.0 0.26 11.4 5.8 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) Tektin PF03148.9 ETO18063.1 - 0.17 10.4 16.4 0.19 10.2 5.3 2.0 1 1 1 2 2 2 0 Tektin family DUF724 PF05266.9 ETO18063.1 - 0.19 11.3 15.4 0.4 10.2 2.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Cast PF10174.4 ETO18063.1 - 0.19 9.7 20.9 4 5.3 14.5 1.9 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Alb1 PF09135.6 ETO18063.1 - 0.2 12.2 7.6 0.71 10.5 0.2 2.1 2 0 0 2 2 2 0 Alb1 WXG100 PF06013.7 ETO18063.1 - 0.26 11.3 6.4 0.14 12.2 1.2 2.2 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DUF641 PF04859.7 ETO18063.1 - 0.29 10.9 13.4 0.67 9.7 2.7 2.1 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) Ax_dynein_light PF10211.4 ETO18063.1 - 0.29 10.9 18.8 1.2 8.9 6.3 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain Streptin-Immun PF11083.3 ETO18063.1 - 0.3 11.0 9.5 0.23 11.4 2.5 2.7 1 1 0 2 2 2 0 Lantibiotic streptin immunity protein Atg14 PF10186.4 ETO18063.1 - 0.3 9.9 15.7 0.58 9.0 5.2 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Prefoldin_2 PF01920.15 ETO18063.1 - 0.34 10.6 22.4 1.1 9.1 3.1 3.1 2 1 1 3 3 3 0 Prefoldin subunit Baculo_PEP_C PF04513.7 ETO18063.1 - 0.35 10.6 11.7 0.7 9.7 2.8 2.1 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lebercilin PF15619.1 ETO18063.1 - 0.36 10.2 20.3 1.1 8.6 7.7 2.0 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Prefoldin PF02996.12 ETO18063.1 - 0.4 10.3 19.2 0.53 9.9 1.5 3.1 1 1 2 3 3 3 0 Prefoldin subunit GrpE PF01025.14 ETO18063.1 - 0.41 10.1 13.6 0.3 10.6 3.8 2.1 1 1 1 2 2 2 0 GrpE DUF848 PF05852.6 ETO18063.1 - 0.45 10.3 15.6 1.8 8.4 10.8 1.8 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) EzrA PF06160.7 ETO18063.1 - 0.46 8.5 14.1 0.65 8.1 9.8 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA YlqD PF11068.3 ETO18063.1 - 0.48 10.4 16.7 0.41 10.6 6.2 2.1 1 1 1 2 2 2 0 YlqD protein TMF_DNA_bd PF12329.3 ETO18063.1 - 0.51 10.1 25.3 0.46 10.3 4.9 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding HAP1_N PF04849.8 ETO18063.1 - 0.54 9.1 18.8 3.6 6.4 13.0 1.8 1 1 0 1 1 1 0 HAP1 N-terminal conserved region DUF4337 PF14235.1 ETO18063.1 - 0.56 10.0 9.1 0.48 10.2 2.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Exonuc_VII_S PF02609.11 ETO18063.1 - 0.57 9.9 11.9 1 9.2 0.5 3.3 3 1 0 3 3 3 0 Exonuclease VII small subunit DUF2443 PF10398.4 ETO18063.1 - 0.57 10.0 7.6 0.75 9.6 0.1 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2443) APG6 PF04111.7 ETO18063.1 - 0.58 9.1 16.2 0.88 8.5 11.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Fib_alpha PF08702.5 ETO18063.1 - 0.68 10.0 15.7 1.2 9.2 4.0 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Pox_A_type_inc PF04508.7 ETO18063.1 - 0.72 9.7 3.8 23 5.1 0.0 3.7 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat ADIP PF11559.3 ETO18063.1 - 0.86 9.4 20.1 5.7 6.8 13.2 2.0 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.1 ETO18063.1 - 0.87 9.5 19.7 0.82 9.6 9.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Kinetocho_Slk19 PF12709.2 ETO18063.1 - 0.87 9.7 20.5 14 5.8 1.5 3.2 1 1 1 2 2 2 0 Central kinetochore-associated PspA_IM30 PF04012.7 ETO18063.1 - 0.99 8.7 16.8 28 3.9 11.5 2.3 1 1 0 1 1 1 0 PspA/IM30 family CALCOCO1 PF07888.6 ETO18063.1 - 1 7.5 13.6 1.3 7.2 9.4 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like AcylCoA_dehyd_C PF12186.3 ETO18063.1 - 1.1 9.1 5.7 0.31 10.9 0.7 2.3 1 1 2 3 3 3 0 Acyl-CoA dehydrogenase C terminal ATG16 PF08614.6 ETO18063.1 - 1.2 8.9 20.4 24 4.6 14.1 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) CHD5 PF04420.9 ETO18063.1 - 1.2 8.7 12.7 3.8 7.1 0.4 2.3 1 1 1 2 2 2 0 CHD5-like protein bZIP_2 PF07716.10 ETO18063.1 - 1.2 9.0 18.3 1.3 8.8 1.0 3.5 3 1 0 3 3 3 0 Basic region leucine zipper XhlA PF10779.4 ETO18063.1 - 1.3 9.0 14.8 1.8 8.5 0.6 2.6 2 1 0 2 2 2 0 Haemolysin XhlA DUF4407 PF14362.1 ETO18063.1 - 1.3 7.8 8.7 1.8 7.4 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Erp_C PF06780.6 ETO18063.1 - 1.4 8.7 14.3 0.98 9.2 6.0 2.2 1 1 1 2 2 2 0 Erp protein C-terminus DUF972 PF06156.8 ETO18063.1 - 1.4 9.3 16.2 3.5 8.0 5.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) SLIDE PF09111.5 ETO18063.1 - 1.4 8.6 8.7 1.9 8.2 0.8 2.1 1 1 1 2 2 2 0 SLIDE DUF310 PF03750.8 ETO18063.1 - 1.5 9.0 5.3 0.78 9.9 1.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF310) TBPIP PF07106.8 ETO18063.1 - 1.5 8.3 20.0 2.7 7.5 7.9 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Allexi_40kDa PF05549.6 ETO18063.1 - 1.6 7.9 9.6 2.7 7.1 6.5 1.5 1 1 0 1 1 1 0 Allexivirus 40kDa protein Nnf1 PF03980.9 ETO18063.1 - 2 8.4 17.6 0.14 12.1 0.9 3.1 2 1 0 2 2 1 0 Nnf1 BRE1 PF08647.6 ETO18063.1 - 2 8.4 18.1 0.42 10.6 5.5 2.1 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase AbiH PF14253.1 ETO18063.1 - 2.1 7.8 9.5 5.6 6.4 6.6 1.7 1 1 0 1 1 1 0 Bacteriophage abortive infection AbiH THOC7 PF05615.8 ETO18063.1 - 2.2 8.5 19.9 15 5.8 7.3 2.6 1 1 1 2 2 2 0 Tho complex subunit 7 IFT57 PF10498.4 ETO18063.1 - 2.3 6.8 17.3 8.4 5.0 11.7 1.9 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Cob_adeno_trans PF01923.13 ETO18063.1 - 2.5 7.8 5.8 4.4 7.0 4.0 1.5 1 1 0 1 1 1 0 Cobalamin adenosyltransferase LXG PF04740.7 ETO18063.1 - 2.6 7.7 14.6 6.5 6.4 0.6 2.0 1 1 1 2 2 2 0 LXG domain of WXG superfamily DUF2316 PF10078.4 ETO18063.1 - 2.8 8.0 6.9 3.5 7.6 0.4 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) DUF2130 PF09903.4 ETO18063.1 - 2.9 6.5 15.4 3.6 6.2 5.7 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) Tropomyosin_1 PF12718.2 ETO18063.1 - 3 7.6 22.3 10 5.9 15.5 1.7 1 1 0 1 1 1 0 Tropomyosin like DUF489 PF04356.7 ETO18063.1 - 3 7.3 8.5 4.2 6.9 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF489) Imm3 PF14425.1 ETO18063.1 - 3.1 7.8 7.5 6.8 6.6 1.6 2.2 2 0 0 2 2 2 0 Immunity protein Imm3 Seryl_tRNA_N PF02403.17 ETO18063.1 - 3.1 7.8 18.0 3.1 7.8 6.4 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4404 PF14357.1 ETO18063.1 - 3.4 8.1 18.1 4.3 7.8 3.5 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4404) RasGAP_C PF03836.10 ETO18063.1 - 4.1 7.0 17.0 2.2 7.9 4.9 2.1 1 1 1 2 2 2 0 RasGAP C-terminus DUF607 PF04678.8 ETO18063.1 - 4.3 7.2 9.9 2 8.3 2.4 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF607 PNPase PF03726.9 ETO18063.1 - 5 7.4 8.3 3.5 7.9 3.4 2.3 1 1 1 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain DUF948 PF06103.6 ETO18063.1 - 5.3 6.9 11.0 2.3 8.1 2.4 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Bacillus_HBL PF05791.6 ETO18063.1 - 5.3 6.3 15.6 1.5e+02 1.6 10.8 2.1 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) bZIP_Maf PF03131.12 ETO18063.1 - 5.5 7.3 16.3 7.6 6.9 1.5 2.4 1 1 1 2 2 2 0 bZIP Maf transcription factor TMCO5 PF14992.1 ETO18063.1 - 5.5 6.0 18.8 23 4.0 12.7 1.6 1 1 0 1 1 1 0 TMCO5 family DDHD PF02862.12 ETO18063.1 - 5.6 6.6 7.9 7.6 6.2 5.5 1.1 1 0 0 1 1 1 0 DDHD domain Syntaxin-6_N PF09177.6 ETO18063.1 - 7.5 7.0 10.7 1.9e+02 2.5 7.4 2.5 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF4446 PF14584.1 ETO18063.1 - 7.6 6.3 11.8 6.4 6.5 2.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF465 PF04325.8 ETO18063.1 - 8.9 6.1 12.4 0.57 9.9 0.1 3.3 2 1 0 2 2 1 0 Protein of unknown function (DUF465) ACCA PF03255.9 ETO18063.1 - 9.4 5.7 10.8 80 2.7 6.1 2.5 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit CENP-F_leu_zip PF10473.4 ETO18064.1 - 0.0015 18.4 7.7 0.0015 18.4 5.4 3.3 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lebercilin PF15619.1 ETO18064.1 - 0.004 16.5 26.8 0.008 15.6 18.5 1.5 1 1 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease ADIP PF11559.3 ETO18064.1 - 0.01 15.7 27.5 0.092 12.6 5.3 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Fez1 PF06818.10 ETO18064.1 - 0.02 14.9 20.4 0.025 14.5 14.1 1.1 1 0 0 1 1 1 0 Fez1 DUF4140 PF13600.1 ETO18064.1 - 0.032 14.6 3.6 0.032 14.6 2.5 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Transcrip_act PF04949.8 ETO18064.1 - 0.035 13.7 14.3 0.19 11.3 6.0 2.2 1 1 1 2 2 2 0 Transcriptional activator Vac_Fusion PF02346.11 ETO18064.1 - 0.038 13.4 0.8 0.038 13.4 0.5 2.9 2 1 0 3 3 3 0 Chordopoxvirus fusion protein DMPK_coil PF08826.5 ETO18064.1 - 0.053 13.4 17.8 0.043 13.7 2.5 3.2 2 2 0 2 2 2 0 DMPK coiled coil domain like Laminin_II PF06009.7 ETO18064.1 - 0.054 13.2 17.7 0.35 10.6 5.7 2.1 1 1 1 2 2 2 0 Laminin Domain II Senescence PF06911.7 ETO18064.1 - 0.083 12.5 0.2 0.14 11.8 0.2 1.3 1 1 0 1 1 1 0 Senescence-associated protein HgmA PF04209.8 ETO18064.1 - 0.1 10.9 0.2 0.11 10.8 0.1 1.2 1 0 0 1 1 1 0 homogentisate 1,2-dioxygenase Filament PF00038.16 ETO18064.1 - 0.12 11.8 22.4 1 8.7 6.5 2.1 1 1 1 2 2 2 0 Intermediate filament protein Tropomyosin PF00261.15 ETO18064.1 - 0.15 11.1 21.7 0.27 10.3 14.6 1.7 1 1 0 1 1 1 0 Tropomyosin Mnd1 PF03962.10 ETO18064.1 - 0.19 11.3 19.4 0.36 10.4 13.5 1.5 1 1 0 1 1 1 0 Mnd1 family Zein-binding PF04576.10 ETO18064.1 - 0.2 11.7 15.7 0.064 13.3 2.1 3.1 1 1 2 3 3 3 0 Zein-binding TMF_DNA_bd PF12329.3 ETO18064.1 - 0.24 11.2 31.7 0.15 11.9 3.8 3.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.7 ETO18064.1 - 0.28 10.9 13.8 0.14 11.9 7.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) MscS_porin PF12795.2 ETO18064.1 - 0.28 10.4 23.4 1.2 8.4 14.9 2.1 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain GAS PF13851.1 ETO18064.1 - 0.29 10.2 27.1 0.42 9.7 8.9 2.1 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding BicD PF09730.4 ETO18064.1 - 0.32 9.3 24.5 0.38 9.0 17.0 1.0 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Spc7 PF08317.6 ETO18064.1 - 0.33 9.5 24.9 0.14 10.8 14.1 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein TBPIP PF07106.8 ETO18064.1 - 0.34 10.4 25.8 0.97 8.9 3.7 2.7 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF812 PF05667.6 ETO18064.1 - 0.38 9.1 23.2 0.53 8.7 16.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Reo_sigmaC PF04582.7 ETO18064.1 - 0.47 9.5 5.4 0.6 9.2 3.2 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 ETO18064.1 - 0.5 8.7 21.0 0.64 8.4 14.6 1.1 1 0 0 1 1 1 0 AAA domain DUF4164 PF13747.1 ETO18064.1 - 0.61 10.2 15.0 0.26 11.4 4.1 3.0 1 1 1 3 3 3 0 Domain of unknown function (DUF4164) Exonuc_VII_L PF02601.10 ETO18064.1 - 0.89 8.6 14.3 1 8.4 9.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF948 PF06103.6 ETO18064.1 - 0.94 9.3 13.8 0.78 9.6 4.6 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) bZIP_1 PF00170.16 ETO18064.1 - 0.94 9.4 19.6 0.45 10.5 2.3 3.5 2 1 0 3 3 3 0 bZIP transcription factor NPV_P10 PF05531.7 ETO18064.1 - 1.3 9.3 13.1 0.33 11.2 3.3 2.9 1 1 3 4 4 4 0 Nucleopolyhedrovirus P10 protein MAD PF05557.8 ETO18064.1 - 2 6.3 28.2 9.5 4.1 19.5 1.8 1 1 0 1 1 1 0 Mitotic checkpoint protein SlyX PF04102.7 ETO18064.1 - 2.1 8.7 20.4 0.58 10.5 2.5 3.6 1 1 2 3 3 3 0 SlyX IncA PF04156.9 ETO18064.1 - 2.2 7.8 27.5 13 5.2 19.1 2.0 1 1 0 1 1 1 0 IncA protein DUF3584 PF12128.3 ETO18064.1 - 2.2 5.5 22.6 3 5.0 15.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CALCOCO1 PF07888.6 ETO18064.1 - 2.5 6.2 23.5 4.9 5.3 16.3 1.5 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF869 PF05911.6 ETO18064.1 - 3.1 5.9 25.6 4.4 5.4 17.7 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) ATG16 PF08614.6 ETO18064.1 - 3.2 7.5 25.2 1.5 8.6 12.0 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) IFT57 PF10498.4 ETO18064.1 - 3.5 6.2 24.2 5.7 5.5 16.7 1.4 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 ERM PF00769.14 ETO18064.1 - 5.5 6.4 24.6 1.1e+02 2.1 8.9 2.0 1 1 0 1 1 1 0 Ezrin/radixin/moesin family USP8_interact PF08941.5 ETO18064.1 - 6.2 6.1 10.2 0.84 8.9 0.9 2.2 2 0 0 2 2 2 0 USP8 interacting DUF730 PF05325.6 ETO18064.1 - 6.8 6.5 10.3 9.8 6.0 0.3 2.9 1 1 3 4 4 4 0 Protein of unknown function (DUF730) MbeD_MobD PF04899.7 ETO18064.1 - 6.9 6.6 13.4 2.3 8.1 3.6 3.3 1 1 2 3 3 3 0 MbeD/MobD like DUF724 PF05266.9 ETO18064.1 - 8.2 5.9 23.9 0.98 9.0 5.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Enkurin PF13864.1 ETO18064.1 - 8.4 6.6 18.7 3 8.1 6.3 2.5 1 1 1 2 2 2 0 Calmodulin-binding Sec3_C_2 PF15278.1 ETO18064.1 - 9 6.5 11.7 0.91 9.6 1.4 2.9 1 1 2 3 3 3 0 Sec3 exocyst complex subunit Fib_alpha PF08702.5 ETO18064.1 - 9.1 6.3 19.9 26 4.9 13.4 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Mu-like_Pro PF10123.4 ETO18064.1 - 9.3 5.6 12.6 2.7 7.3 6.5 1.5 1 1 1 2 2 2 0 Mu-like prophage I protein AAA_17 PF13207.1 ETO18066.1 - 0.00077 20.2 4.5 0.0033 18.2 0.0 3.7 3 1 0 3 3 3 1 AAA domain ADK PF00406.17 ETO18066.1 - 0.23 11.3 0.0 0.23 11.3 0.0 3.2 3 0 0 3 3 3 0 Adenylate kinase AAA_18 PF13238.1 ETO18066.1 - 0.4 10.9 0.0 0.4 10.9 0.0 5.3 4 1 0 4 4 4 0 AAA domain HEAT PF02985.17 ETO18067.1 - 0.05 13.7 0.3 1.1 9.5 0.3 2.9 3 0 0 3 3 3 0 HEAT repeat Snapin_Pallidin PF14712.1 ETO18070.1 - 0.006 16.8 5.1 0.006 16.8 3.5 2.4 1 1 2 3 3 3 1 Snapin/Pallidin Vps51 PF08700.6 ETO18070.1 - 0.006 16.3 10.5 0.02 14.7 0.7 3.0 1 1 1 2 2 2 2 Vps51/Vps67 Adenylsucc_synt PF00709.16 ETO18070.1 - 0.018 13.6 1.7 0.026 13.1 1.2 1.2 1 0 0 1 1 1 0 Adenylosuccinate synthetase HAP1_N PF04849.8 ETO18070.1 - 0.089 11.7 10.2 0.12 11.3 7.1 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region chaperone_DMP PF10448.4 ETO18071.1 - 0.046 13.6 1.7 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 20S proteasome chaperone DUF3439 PF11921.3 ETO18071.1 - 0.055 13.2 4.0 0.093 12.4 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Methyltransf_11 PF08241.7 ETO18072.1 - 8.3e-07 29.4 0.0 2.3e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETO18072.1 - 2.6e-05 23.9 0.0 3.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO18072.1 - 0.00083 19.7 0.0 0.002 18.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETO18072.1 - 0.00083 18.5 0.0 0.0031 16.6 0.0 1.7 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 ETO18072.1 - 0.00088 18.8 0.1 0.003 17.1 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain His_Phos_1 PF00300.17 ETO18073.1 - 0.006 16.6 0.1 0.032 14.3 0.0 2.0 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 1) SSP160 PF06933.6 ETO18073.1 - 0.025 12.5 7.5 0.03 12.3 5.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Macoilin PF09726.4 ETO18073.1 - 0.13 10.5 11.6 0.13 10.4 8.0 1.1 1 0 0 1 1 1 0 Transmembrane protein POX PF07526.6 ETO18073.1 - 0.29 11.3 5.3 0.48 10.6 3.7 1.3 1 0 0 1 1 1 0 Associated with HOX Presenilin PF01080.12 ETO18073.1 - 0.95 8.2 3.1 1 8.1 2.2 1.2 1 0 0 1 1 1 0 Presenilin DUF4614 PF15391.1 ETO18073.1 - 3.1 7.5 11.8 4.5 6.9 8.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) FH2 PF02181.18 ETO18075.1 - 2.1e-26 92.6 2.2 3e-26 92.1 1.5 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain IBR PF01485.16 ETO18077.1 - 1.2e-19 69.9 28.9 3e-11 43.0 6.3 4.2 4 1 0 4 4 4 3 IBR domain zf-C3HC4_3 PF13920.1 ETO18077.1 - 0.031 13.9 0.5 0.031 13.9 0.4 5.7 4 2 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Cortex-I_coil PF09304.5 ETO18078.1 - 0.13 12.2 0.1 0.19 11.8 0.1 1.2 1 0 0 1 1 1 0 Cortexillin I, coiled coil zf-C2H2_2 PF12756.2 ETO18079.1 - 0.061 13.4 0.3 0.17 12.0 0.2 1.7 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) CDC37_C PF08564.5 ETO18079.1 - 0.11 12.3 0.1 0.11 12.3 0.0 2.4 3 1 0 3 3 3 0 Cdc37 C terminal domain V_ATPase_I PF01496.14 ETO18080.1 - 0.061 11.1 16.1 0.083 10.7 11.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prismane PF03063.15 ETO18080.1 - 1.4 7.1 8.1 2.1 6.6 5.6 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family IncA PF04156.9 ETO18080.1 - 1.4 8.4 20.7 2.9 7.4 14.4 1.5 1 0 0 1 1 1 0 IncA protein Exo_endo_phos_2 PF14529.1 ETO18081.1 - 8.6e-11 41.4 1.1 8.6e-11 41.4 0.8 1.7 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 ETO18081.1 - 0.085 12.7 0.0 0.32 10.9 0.0 1.9 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF3584 PF12128.3 ETO18082.1 - 0.34 8.1 50.3 0.47 7.7 34.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF912 PF06024.7 ETO18083.1 - 0.069 13.2 0.5 0.76 9.8 0.1 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ApoL PF05461.6 ETO18084.1 - 0.01 15.0 2.9 0.025 13.8 1.2 2.1 1 1 1 2 2 2 0 Apolipoprotein L Baculo_PEP_C PF04513.7 ETO18084.1 - 0.048 13.4 5.4 1.5 8.6 0.4 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2203 PF09969.4 ETO18084.1 - 0.37 11.0 9.7 4.2 7.6 0.2 3.3 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF3713 PF12506.3 ETO18084.1 - 0.45 10.5 3.3 3.8 7.6 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3713) THOC7 PF05615.8 ETO18084.1 - 0.46 10.7 14.3 0.4 10.9 4.1 3.3 2 1 1 3 3 3 0 Tho complex subunit 7 HisKA_3 PF07730.8 ETO18084.1 - 0.92 9.8 8.9 17 5.8 0.2 4.0 3 1 1 4 4 4 0 Histidine kinase Snapin_Pallidin PF14712.1 ETO18084.1 - 1.2 9.4 11.6 0.54 10.5 1.6 2.8 3 0 0 3 3 3 0 Snapin/Pallidin Tox-REase-5 PF15648.1 ETO18084.1 - 1.3 9.3 4.1 0.36 11.1 0.1 2.1 3 0 0 3 3 1 0 Restriction endonuclease fold toxin 5 DUF1664 PF07889.7 ETO18084.1 - 2 8.1 8.2 0.83 9.4 1.1 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) DUF342 PF03961.8 ETO18084.1 - 2.5 6.3 14.2 5.6 5.2 3.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF342) Cauli_AT PF03233.8 ETO18084.1 - 3.5 7.3 6.4 0.58 9.8 0.2 2.6 3 1 1 4 4 4 0 Aphid transmission protein Tweety PF04906.8 ETO18084.1 - 3.7 5.8 8.4 0.77 8.1 0.5 2.3 2 1 1 3 3 3 0 Tweety Phage_GPO PF05929.6 ETO18084.1 - 3.7 6.7 7.1 1.4 8.1 1.9 2.1 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase TBCA PF02970.11 ETO18084.1 - 6.1 6.9 12.3 12 6.0 0.8 2.9 1 1 1 3 3 3 0 Tubulin binding cofactor A Sipho_Gp157 PF05565.6 ETO18084.1 - 8 6.0 9.7 2.3 7.7 1.3 2.8 4 0 0 4 4 4 0 Siphovirus Gp157 IncA PF04156.9 ETO18084.1 - 8.6 5.9 26.6 6.3 6.3 14.0 2.9 2 1 0 2 2 2 0 IncA protein TPR_11 PF13414.1 ETO18085.1 - 0.068 12.8 0.6 0.39 10.3 0.3 2.0 2 0 0 2 2 2 0 TPR repeat RNA_pol_Rpb2_4 PF04566.8 ETO18086.1 - 0.12 12.1 0.1 4 7.3 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 4 DUF3944 PF13099.1 ETO18087.1 - 0.072 12.6 0.0 0.18 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3944) Pkinase PF00069.20 ETO18088.1 - 1.5e-51 175.0 0.0 5.1e-51 173.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO18088.1 - 4e-49 167.0 0.0 8.5e-31 106.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 ETO18088.1 - 0.067 12.5 0.4 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL VQ PF05678.9 ETO18088.1 - 0.55 9.3 2.2 1.1 8.3 1.6 1.4 1 0 0 1 1 1 0 VQ motif Tropomyosin_1 PF12718.2 ETO18089.1 - 5 6.9 32.3 0.56 10.0 6.4 4.1 2 1 0 3 3 3 0 Tropomyosin like AHS1 PF02682.11 ETO18089.1 - 8.2 5.8 8.7 1.7 8.0 0.9 2.5 2 1 1 3 3 3 0 Allophanate hydrolase subunit 1 SH3BGR PF04908.10 ETO18090.1 - 0.047 13.6 0.2 0.11 12.4 0.1 1.6 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein CDKN3 PF05706.7 ETO18092.1 - 7.3e-09 35.2 0.1 1.3e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.22 ETO18092.1 - 3.2e-07 29.9 2.6 3e-05 23.4 0.7 2.9 1 1 1 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.15 ETO18092.1 - 1.1e-05 24.9 0.7 2.9e-05 23.6 0.1 1.9 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 ETO18092.1 - 0.00026 21.2 0.3 0.00076 19.7 0.2 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 ETO18092.1 - 0.0048 16.9 0.1 0.011 15.7 0.1 1.6 1 1 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.8 ETO18092.1 - 0.029 13.7 0.1 0.042 13.2 0.1 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family G-alpha PF00503.15 ETO18094.1 - 3.5e-16 58.8 0.0 4.7e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Rad17 PF03215.10 ETO18094.1 - 0.0022 16.7 0.0 0.0037 16.0 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein ABC_tran PF00005.22 ETO18094.1 - 0.006 16.8 0.1 0.0081 16.4 0.1 1.3 1 1 0 1 1 1 1 ABC transporter Mg_chelatase PF01078.16 ETO18094.1 - 0.012 14.7 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 ETO18094.1 - 0.019 15.1 0.0 0.05 13.7 0.0 1.7 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.17 ETO18094.1 - 0.021 13.7 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.1 ETO18094.1 - 0.026 14.0 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 ETO18094.1 - 0.03 14.3 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 ETO18094.1 - 0.03 14.5 0.0 0.044 13.9 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 ETO18094.1 - 0.032 15.0 0.0 0.047 14.4 0.0 1.3 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 ETO18094.1 - 0.038 13.4 0.2 0.094 12.2 0.1 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 ETO18094.1 - 0.049 13.3 0.0 0.071 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 ETO18094.1 - 0.05 12.7 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 ETO18094.1 - 0.051 13.8 0.0 0.056 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 ETO18094.1 - 0.055 13.3 0.1 0.077 12.8 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 ETO18094.1 - 0.079 12.8 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 ETO18094.1 - 0.11 12.0 0.0 0.43 10.1 0.0 1.7 1 1 1 2 2 2 0 AAA domain PRK PF00485.13 ETO18094.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family CAP_GLY PF01302.20 ETO18095.1 - 2.3e-16 59.2 0.6 4.3e-16 58.3 0.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain ETRAMP PF09716.5 ETO18097.1 - 0.0051 16.7 4.7 0.0051 16.7 3.3 2.1 2 1 0 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) ArdA PF07275.6 ETO18097.1 - 0.006 16.8 0.1 0.0077 16.4 0.1 1.1 1 0 0 1 1 1 1 Antirestriction protein (ArdA) OAD_gamma PF04277.8 ETO18097.1 - 0.015 15.6 0.9 0.036 14.4 0.1 2.0 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Ion_trans PF00520.26 ETO18097.1 - 0.036 13.3 0.6 0.04 13.1 0.4 1.1 1 0 0 1 1 1 0 Ion transport protein DUF4446 PF14584.1 ETO18097.1 - 0.072 12.9 1.6 0.083 12.7 0.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) EphA2_TM PF14575.1 ETO18097.1 - 0.079 13.3 1.5 0.43 10.9 0.1 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4293 PF14126.1 ETO18097.1 - 0.09 12.6 0.4 0.24 11.2 0.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) Mad3_BUB1_II PF08171.6 ETO18097.1 - 0.15 11.9 0.1 0.15 11.9 0.1 2.2 2 1 0 2 2 2 0 Mad3/BUB1 homology region 2 ATP-synt_8 PF00895.15 ETO18097.1 - 0.16 12.2 6.9 1.7 8.9 0.5 2.6 2 0 0 2 2 2 0 ATP synthase protein 8 DUF843 PF05814.6 ETO18097.1 - 0.49 10.2 10.0 0.099 12.4 3.0 2.4 2 1 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) PDR_CDR PF06422.7 ETO18097.1 - 0.96 9.1 6.3 0.52 10.0 1.2 2.1 2 0 0 2 2 2 0 CDR ABC transporter DUF2252 PF10009.4 ETO18097.1 - 1 8.2 0.0 1 8.2 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2252) DUF2183 PF09949.4 ETO18097.1 - 4.6 7.2 7.9 2.5 8.0 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) UPF0542 PF15086.1 ETO18097.1 - 5.5 6.7 11.4 0.58 9.9 2.7 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 DUF4163 PF13739.1 ETO18097.1 - 5.8 7.7 11.6 3.6 8.4 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4163) RGS PF00615.14 ETO18098.1 - 0.0014 18.6 0.6 0.02 14.9 0.0 2.2 1 1 1 2 2 2 1 Regulator of G protein signaling domain KfrA_N PF11740.3 ETO18098.1 - 0.085 13.3 0.4 0.63 10.4 0.4 1.9 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term RGS-like PF09128.6 ETO18098.1 - 0.28 10.6 3.2 0.2 11.1 0.1 2.0 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain Dynamin_N PF00350.18 ETO18099.1 - 2.1e-16 60.1 0.1 3e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 ETO18099.1 - 3.8e-06 26.8 0.0 2e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 ETO18099.1 - 0.001 19.5 0.3 0.0018 18.7 0.2 1.6 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 ETO18099.1 - 0.0066 15.9 0.1 0.03 13.7 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 ETO18099.1 - 0.081 13.2 0.2 0.13 12.5 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_21 PF13304.1 ETO18099.1 - 0.1 12.5 4.0 0.031 14.2 0.9 1.6 2 0 0 2 2 2 0 AAA domain Dynamin_M PF01031.15 ETO18100.1 - 3.7e-22 78.4 11.7 2.5e-13 49.4 3.7 2.4 2 1 0 2 2 2 2 Dynamin central region GED PF02212.13 ETO18100.1 - 2.8e-07 30.3 1.1 2.8e-07 30.3 0.7 2.6 2 0 0 2 2 2 1 Dynamin GTPase effector domain CobU PF02283.11 ETO18100.1 - 0.053 12.9 0.4 0.14 11.5 0.3 1.7 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase DUF4261 PF14080.1 ETO18100.1 - 0.074 12.8 0.1 13 5.6 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4261) DUF3619 PF12279.3 ETO18100.1 - 0.089 12.8 0.9 0.21 11.6 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) Peptidase_M75 PF09375.5 ETO18100.1 - 0.12 11.6 1.1 0.21 10.8 0.7 1.3 1 0 0 1 1 1 0 Imelysin GAGA_bind PF06217.7 ETO18100.1 - 0.13 12.2 2.3 0.25 11.2 1.6 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Ank_2 PF12796.2 ETO18101.1 - 1.7e-34 118.0 0.1 4.7e-17 62.0 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETO18101.1 - 1.8e-28 96.8 0.9 1.7e-09 37.0 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 ETO18101.1 - 4.2e-26 90.3 1.2 1.4e-10 41.0 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO18101.1 - 3.2e-24 82.5 1.0 4.1e-05 23.4 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 ETO18101.1 - 4.9e-22 77.8 4.9 4.1e-10 39.9 0.1 3.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) DUF249 PF03158.8 ETO18101.1 - 0.00084 18.9 1.6 0.42 10.1 0.2 2.7 2 1 1 3 3 3 2 Multigene family 530 protein XRCC4 PF06632.7 ETO18102.1 - 0.00089 18.2 2.1 0.0013 17.6 1.4 1.3 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 WD40 PF00400.27 ETO18103.1 - 8.3e-14 50.8 0.8 1.8e-11 43.4 0.1 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Spo7 PF03907.8 ETO18103.1 - 0.03 13.9 0.5 0.037 13.6 0.3 1.1 1 0 0 1 1 1 0 Spo7-like protein ODV-E18 PF10717.4 ETO18103.1 - 0.08 12.3 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 LRR_4 PF12799.2 ETO18104.1 - 9.5e-28 95.3 28.8 6e-10 38.5 0.1 8.4 6 2 2 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO18104.1 - 6.9e-15 54.5 25.3 4.1e-06 26.4 0.6 6.3 3 2 5 8 8 8 7 Leucine rich repeat LRR_1 PF00560.28 ETO18104.1 - 4.2e-13 47.3 27.4 0.082 12.9 0.0 10.4 10 0 0 10 10 10 5 Leucine Rich Repeat LRR_6 PF13516.1 ETO18104.1 - 1.5e-06 27.6 18.1 2.9 8.2 0.1 9.1 8 3 1 10 10 10 3 Leucine Rich repeat LRR_7 PF13504.1 ETO18104.1 - 1.1e-05 24.8 25.6 1.8 9.1 0.0 10.1 12 1 0 12 12 12 3 Leucine rich repeat LRR_9 PF14580.1 ETO18104.1 - 3.5e-05 23.4 9.5 0.0031 17.0 0.6 3.1 1 1 2 3 3 3 2 Leucine-rich repeat Ribosomal_L18e PF00828.14 ETO18105.1 - 7.5e-28 97.4 0.1 1.4e-27 96.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Ank_5 PF13857.1 ETO18106.1 - 0.00064 19.8 0.0 0.0016 18.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO18106.1 - 0.0016 18.9 0.0 0.76 10.3 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO18106.1 - 0.0082 16.4 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO18106.1 - 0.12 12.6 0.0 35 5.0 0.0 3.0 2 0 0 2 2 2 0 Ankyrin repeat FTCD_C PF04961.7 ETO18106.1 - 2.6 7.4 5.3 8.3 5.7 0.1 2.5 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase DUF1626 PF07788.6 ETO18107.1 - 0.0017 18.1 0.1 0.003 17.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1626) BSD PF03909.12 ETO18108.1 - 2.2e-06 27.2 0.5 5.3e-06 26.0 0.3 1.6 1 0 0 1 1 1 1 BSD domain TFIIA PF03153.8 ETO18108.1 - 0.011 15.6 31.3 0.02 14.8 21.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UBA_4 PF14555.1 ETO18109.1 - 1.3e-07 30.9 0.9 2e-07 30.3 0.6 1.4 1 0 0 1 1 1 1 UBA-like domain DNA_gyraseB PF00204.20 ETO18110.1 - 0.018 14.2 0.1 0.027 13.6 0.1 1.2 1 0 0 1 1 1 0 DNA gyrase B TRAP_alpha PF03896.11 ETO18111.1 - 1.7 7.5 12.6 2.2 7.2 7.5 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit U1snRNP70_N PF12220.3 ETO18111.1 - 5.4 7.4 14.6 9.5 6.6 2.9 3.1 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Ank_2 PF12796.2 ETO18112.1 - 0.0037 17.5 0.0 0.0092 16.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO18112.1 - 0.0038 17.3 0.3 0.034 14.3 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.25 ETO18112.1 - 0.004 16.8 1.4 0.0053 16.5 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 ETO18112.1 - 0.0096 16.4 0.0 0.046 14.2 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) LUC7 PF03194.10 ETO18112.1 - 1.9 7.9 10.7 0.069 12.6 3.5 1.4 2 0 0 2 2 2 0 LUC7 N_terminus CHDNT PF08073.7 ETO18113.1 - 0.011 15.3 0.2 0.023 14.3 0.1 1.6 1 0 0 1 1 1 0 CHDNT (NUC034) domain SPX PF03105.14 ETO18113.1 - 1.9 8.1 40.1 0.0069 16.2 19.9 2.5 1 1 1 2 2 2 0 SPX domain CDC45 PF02724.9 ETO18113.1 - 5.1 5.0 23.8 0.86 7.5 14.0 1.4 2 0 0 2 2 2 0 CDC45-like protein Menin PF05053.8 ETO18113.1 - 9.8 4.2 22.3 4.6 5.2 14.1 1.4 1 1 0 1 1 1 0 Menin Bromodomain PF00439.20 ETO18115.1 - 2.2e-25 88.3 0.4 3.5e-25 87.7 0.3 1.3 1 0 0 1 1 1 1 Bromodomain AMP-binding_C_2 PF14535.1 ETO18115.1 - 0.093 12.7 0.3 1.3 9.0 0.0 2.2 1 1 0 2 2 2 0 AMP-binding enzyme C-terminal domain CAP_N PF01213.14 ETO18116.1 - 0.13 11.4 1.6 0.18 11.0 1.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DHquinase_II PF01220.14 ETO18118.1 - 0.0096 15.2 1.3 0.013 14.8 0.9 1.1 1 0 0 1 1 1 1 Dehydroquinase class II FAM91_C PF14648.1 ETO18118.1 - 0.06 12.1 0.9 0.064 12.0 0.6 1.0 1 0 0 1 1 1 0 FAM91 C-terminus P5-ATPase PF12409.3 ETO18118.1 - 0.92 9.3 4.5 1.2 8.9 3.1 1.2 1 0 0 1 1 1 0 P5-type ATPase cation transporter NPCC PF08058.6 ETO18118.1 - 0.94 9.3 5.0 0.25 11.2 0.5 1.9 1 1 1 2 2 2 0 Nuclear pore complex component YjgP_YjgQ PF03739.9 ETO18118.1 - 1 8.0 4.2 1.1 7.8 2.9 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Protocadherin PF08374.6 ETO18118.1 - 1.1 8.7 6.5 1.4 8.4 4.5 1.1 1 0 0 1 1 1 0 Protocadherin FimP PF09766.4 ETO18119.1 - 0.001 18.2 6.1 0.0014 17.7 4.2 1.1 1 0 0 1 1 1 1 Fms-interacting protein 5TM-5TMR_LYT PF07694.7 ETO18119.1 - 0.0043 16.4 0.9 0.011 15.0 0.6 1.6 1 0 0 1 1 1 1 5TMR of 5TMR-LYT DUF2910 PF11139.3 ETO18119.1 - 0.1 11.7 4.7 1.4 8.0 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2910) Pex14_N PF04695.8 ETO18119.1 - 0.73 9.8 10.0 1.5 8.8 7.0 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region bZIP_C PF12498.3 ETO18119.1 - 1.2 10.4 13.8 2.4 9.3 9.5 1.4 1 0 0 1 1 1 0 Basic leucine-zipper C terminal Secretin_N_2 PF07655.8 ETO18119.1 - 4.2 7.8 31.5 8.1 6.9 21.8 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain G-alpha PF00503.15 ETO18120.1 - 1.4e-26 93.1 0.3 1.6e-26 92.8 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO18120.1 - 3.3e-08 32.9 0.3 6.3e-08 32.0 0.2 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family DUF3048 PF11258.3 ETO18120.1 - 0.11 11.5 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3048) SAM_2 PF07647.12 ETO18121.1 - 0.00011 21.9 0.0 0.0002 21.1 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO18121.1 - 0.028 14.6 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Nop14 PF04147.7 ETO18121.1 - 1.3 6.8 60.7 0.031 12.2 11.9 2.1 2 0 0 2 2 2 0 Nop14-like family MIB_HERC2 PF06701.8 ETO18122.1 - 7.9e-19 67.3 6.5 7.9e-19 67.3 4.5 2.1 3 0 0 3 3 3 1 Mib_herc2 Ank_2 PF12796.2 ETO18123.1 - 0.011 15.9 0.0 0.19 12.0 0.1 2.5 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO18124.1 - 3.6e-05 24.1 0.0 0.00098 19.5 0.0 2.9 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.25 ETO18124.1 - 0.00018 21.1 0.0 12 5.9 0.0 4.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 ETO18124.1 - 0.0015 18.6 0.1 2.6 8.4 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO18124.1 - 0.017 15.3 0.2 52 4.5 0.0 4.3 5 1 0 5 5 5 0 Ankyrin repeat TPR_11 PF13414.1 ETO18125.1 - 1.3e-19 69.5 8.3 2.3e-09 36.7 0.9 3.1 2 1 0 3 3 3 3 TPR repeat TPR_2 PF07719.12 ETO18125.1 - 7.1e-15 53.6 12.0 1.2e-06 27.9 0.0 5.0 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO18125.1 - 7.6e-15 53.7 9.5 2.4e-07 30.0 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO18125.1 - 1.7e-12 47.4 0.1 1.9e-07 31.2 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETO18125.1 - 2.4e-11 43.3 0.1 5.1e-08 32.6 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO18125.1 - 2.6e-11 43.8 0.3 2.7e-05 24.6 0.1 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO18125.1 - 5.2e-11 41.4 6.3 7e-06 25.4 0.0 4.5 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO18125.1 - 1.8e-09 37.0 0.9 0.0051 16.9 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO18125.1 - 2.9e-08 33.7 7.3 2.1e-06 27.7 0.3 2.6 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 ETO18125.1 - 9.7e-08 31.2 1.0 0.00015 21.3 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO18125.1 - 1.3e-07 31.5 0.1 0.00071 19.9 0.0 4.0 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO18125.1 - 4.8e-06 26.4 8.7 0.083 12.8 0.4 3.5 1 1 3 4 4 4 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO18125.1 - 1.1e-05 25.2 6.1 0.0022 17.8 0.2 3.4 3 1 1 4 4 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 ETO18125.1 - 2.4e-05 24.4 1.9 0.012 15.9 0.0 4.0 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.1 ETO18125.1 - 0.0027 17.7 0.2 0.34 11.0 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat YfiO PF13525.1 ETO18125.1 - 0.008 15.6 2.1 0.37 10.2 0.2 3.0 2 1 0 2 2 2 1 Outer membrane lipoprotein TPR_15 PF13429.1 ETO18125.1 - 0.028 13.4 0.5 4.8 6.1 0.0 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO18125.1 - 0.06 12.6 0.1 0.6 9.3 0.0 2.5 3 0 0 3 3 3 0 SHNi-TPR MIT PF04212.13 ETO18125.1 - 0.11 12.4 0.3 27 4.7 0.0 3.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain HSP90 PF00183.13 ETO18126.1 - 0.085 11.2 0.2 0.097 11.0 0.1 1.0 1 0 0 1 1 1 0 Hsp90 protein ClpB_D2-small PF10431.4 ETO18127.1 - 7e-09 35.4 0.3 1e-08 34.9 0.2 1.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Decorin_bind PF02352.10 ETO18127.1 - 0.012 15.5 0.7 0.013 15.4 0.5 1.2 1 0 0 1 1 1 0 Decorin binding protein EF-hand_7 PF13499.1 ETO18128.1 - 5.6e-12 45.6 3.5 1.4e-08 34.7 0.5 3.6 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 ETO18128.1 - 1.7e-10 39.3 5.6 1.3e-05 24.0 0.2 5.2 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.1 ETO18128.1 - 5.3e-09 35.2 3.1 0.0032 17.2 0.1 5.2 5 0 0 5 5 5 2 EF-hand domain EF-hand_5 PF13202.1 ETO18128.1 - 5.4e-06 25.5 6.6 5.8e-06 25.4 0.3 3.4 3 1 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 ETO18128.1 - 1.7e-05 24.3 3.5 0.00066 19.2 0.1 4.1 4 1 0 4 4 4 1 EF-hand domain pair Pkinase PF00069.20 ETO18129.1 - 4.1e-10 39.2 0.0 7.1e-10 38.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO18129.1 - 7e-06 25.3 0.0 1.1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1910 PF08928.5 ETO18129.1 - 0.1 12.5 0.6 0.19 11.7 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) AIF_C PF14721.1 ETO18129.1 - 0.29 11.3 2.5 0.42 10.8 0.9 1.8 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Sigma70_ner PF04546.8 ETO18132.1 - 0.0032 17.1 9.1 0.0035 16.9 6.3 1.1 1 0 0 1 1 1 1 Sigma-70, non-essential region Atrophin-1 PF03154.10 ETO18132.1 - 0.0054 14.9 6.3 0.0057 14.8 4.4 1.1 1 0 0 1 1 1 1 Atrophin-1 family TPR_19 PF14559.1 ETO18132.1 - 0.006 16.8 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF1510 PF07423.6 ETO18132.1 - 0.011 15.1 9.9 0.011 15.0 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Apc3 PF12895.2 ETO18132.1 - 0.021 14.9 0.1 0.042 13.9 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 HABP4_PAI-RBP1 PF04774.10 ETO18132.1 - 0.052 14.0 12.5 0.064 13.7 8.6 1.2 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family Trypan_PARP PF05887.6 ETO18132.1 - 0.067 13.0 0.3 0.075 12.8 0.2 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Rtf2 PF04641.7 ETO18132.1 - 0.071 12.2 8.6 0.092 11.9 6.0 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Zip PF02535.17 ETO18132.1 - 0.077 11.9 4.2 0.076 12.0 2.9 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2146 PF10220.4 ETO18132.1 - 0.08 10.9 5.6 0.092 10.7 3.9 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Peptidase_C37 PF05416.7 ETO18132.1 - 0.096 10.9 1.6 0.1 10.8 1.1 1.0 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Ycf1 PF05758.7 ETO18132.1 - 0.14 9.8 5.4 0.14 9.8 3.7 1.0 1 0 0 1 1 1 0 Ycf1 Prog_receptor PF02161.10 ETO18132.1 - 0.18 10.5 3.4 0.18 10.5 2.3 1.0 1 0 0 1 1 1 0 Progesterone receptor SID-1_RNA_chan PF13965.1 ETO18132.1 - 0.22 9.6 2.5 0.21 9.6 1.7 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Vfa1 PF08432.5 ETO18132.1 - 0.33 10.9 14.9 0.4 10.6 10.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Presenilin PF01080.12 ETO18132.1 - 0.36 9.6 2.2 0.36 9.5 1.6 1.1 1 0 0 1 1 1 0 Presenilin SelP_N PF04592.9 ETO18132.1 - 0.43 9.9 8.4 0.49 9.7 5.8 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RNA_polI_A34 PF08208.6 ETO18132.1 - 0.49 10.0 20.6 0.57 9.8 14.3 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Metaviral_G PF09595.5 ETO18132.1 - 0.5 9.9 9.2 0.58 9.7 6.4 1.0 1 0 0 1 1 1 0 Metaviral_G glycoprotein Paramyxo_ncap PF00973.14 ETO18132.1 - 0.65 8.6 5.1 0.72 8.4 3.5 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein RP-C_C PF11800.3 ETO18132.1 - 0.88 9.2 8.2 0.97 9.0 5.7 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region RR_TM4-6 PF06459.7 ETO18132.1 - 1.2 8.9 12.3 1.4 8.7 8.5 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.3 ETO18132.1 - 1.4 7.3 10.1 1.7 7.1 7.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.9 ETO18132.1 - 1.8 6.4 10.3 1.9 6.3 7.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Med19 PF10278.4 ETO18132.1 - 2.7 7.6 14.8 3.1 7.4 10.3 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 SspB PF04386.8 ETO18132.1 - 3.2 7.3 7.8 4.6 6.8 5.4 1.2 1 0 0 1 1 1 0 Stringent starvation protein B Sec62 PF03839.11 ETO18132.1 - 4.5 6.6 13.5 5.3 6.3 9.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 RNA_pol_Rpc4 PF05132.9 ETO18132.1 - 7.8 6.4 11.8 10 6.1 8.2 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF3537 PF12056.3 ETO18132.1 - 8.7 4.9 6.0 11 4.5 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) Glyco_transf_34 PF05637.7 ETO18133.1 - 0.016 14.7 6.1 0.75 9.2 0.8 2.6 2 0 0 2 2 2 0 galactosyl transferase GMA12/MNN10 family Menin PF05053.8 ETO18134.1 - 0.00049 18.4 8.8 0.00051 18.3 6.1 1.0 1 0 0 1 1 1 1 Menin Apis_Csd PF11671.3 ETO18134.1 - 0.033 14.0 22.1 0.044 13.5 15.3 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein Neur_chan_memb PF02932.11 ETO18134.1 - 0.077 12.8 6.0 0.11 12.3 4.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM60A PF15396.1 ETO18134.1 - 0.13 11.9 9.4 0.15 11.7 6.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF1675 PF07897.6 ETO18134.1 - 0.17 11.7 12.5 0.21 11.4 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Sec62 PF03839.11 ETO18134.1 - 0.8 9.0 9.1 1 8.7 6.3 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Tim54 PF11711.3 ETO18134.1 - 0.83 8.1 8.3 1.1 7.7 5.8 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.9 ETO18134.1 - 0.88 7.5 13.8 0.86 7.5 9.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Secretin_N_2 PF07655.8 ETO18134.1 - 0.94 9.9 19.1 1.3 9.4 13.3 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain DUF3807 PF12720.2 ETO18134.1 - 1.2 9.3 20.0 1.5 9.0 13.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF1390 PF07150.6 ETO18134.1 - 1.5 8.1 13.1 1.8 7.8 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) Nop14 PF04147.7 ETO18134.1 - 1.6 6.5 21.7 1.9 6.3 15.0 1.0 1 0 0 1 1 1 0 Nop14-like family Nop25 PF09805.4 ETO18134.1 - 4.6 7.3 22.8 5.8 6.9 15.8 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) LMBR1 PF04791.11 ETO18134.1 - 5.6 5.4 7.3 6.2 5.2 5.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Presenilin PF01080.12 ETO18134.1 - 9.1 4.9 10.1 9.7 4.8 7.0 1.1 1 0 0 1 1 1 0 Presenilin SAPS PF04499.10 ETO18134.1 - 10 4.6 17.3 10 4.5 12.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mucin PF01456.12 ETO18135.1 - 0.0021 17.8 2.5 0.0022 17.7 1.0 1.6 2 0 0 2 2 2 1 Mucin-like glycoprotein PH PF00169.24 ETO18135.1 - 0.0034 17.5 0.3 0.0067 16.6 0.2 1.6 1 1 0 1 1 1 1 PH domain BSP_II PF05432.6 ETO18135.1 - 0.075 12.3 10.0 0.094 11.9 6.9 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Strumpellin PF10266.4 ETO18136.1 - 2.5e-111 372.9 7.4 3e-111 372.6 5.1 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin Kelch_1 PF01344.20 ETO18137.1 - 0.019 14.5 0.2 0.042 13.3 0.1 1.7 1 0 0 1 1 1 0 Kelch motif Kelch_6 PF13964.1 ETO18137.1 - 0.031 14.4 0.6 0.061 13.5 0.3 1.6 1 1 0 1 1 1 0 Kelch motif CAP_GLY PF01302.20 ETO18138.1 - 1.4e-12 47.1 0.2 2.4e-12 46.3 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain SEEEED PF14797.1 ETO18138.1 - 3.6 7.7 26.4 1.9 8.6 16.5 1.7 1 1 1 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex Daxx PF03344.10 ETO18139.1 - 1.2e-08 34.0 12.7 1.5e-08 33.6 8.8 1.1 1 0 0 1 1 1 1 Daxx Family Astro_capsid PF03115.9 ETO18139.1 - 0.04 12.1 3.3 0.057 11.6 2.3 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor RRN3 PF05327.6 ETO18139.1 - 0.08 11.0 4.8 0.11 10.5 3.3 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PPP4R2 PF09184.6 ETO18139.1 - 0.088 12.3 19.2 0.23 10.9 13.3 1.7 1 0 0 1 1 1 0 PPP4R2 DUF2722 PF10846.3 ETO18139.1 - 0.14 11.1 14.8 0.06 12.3 6.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) NOA36 PF06524.7 ETO18139.1 - 0.28 10.4 14.6 0.45 9.7 10.1 1.3 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.6 ETO18139.1 - 0.37 10.5 12.6 0.79 9.5 8.7 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC45 PF02724.9 ETO18139.1 - 0.7 7.8 15.8 1.3 6.9 10.9 1.4 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.8 ETO18139.1 - 1.1 9.0 22.3 0.23 11.3 11.5 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Herpes_LMP1 PF05297.6 ETO18139.1 - 1.5 7.6 9.4 2.3 7.0 6.5 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) SDA1 PF05285.7 ETO18139.1 - 1.8 7.7 20.8 3.2 6.9 14.4 1.4 1 0 0 1 1 1 0 SDA1 Nucleo_P87 PF07267.6 ETO18139.1 - 1.8 7.1 10.4 3 6.4 7.2 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TFIIF_alpha PF05793.7 ETO18139.1 - 2.4 6.4 21.3 3.4 5.9 14.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pox_Ag35 PF03286.9 ETO18139.1 - 2.4 7.6 13.8 4.5 6.7 9.6 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FLO_LFY PF01698.11 ETO18139.1 - 2.7 6.7 6.7 5.5 5.7 4.6 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein WD40 PF00400.27 ETO18140.1 - 2.9e-30 103.0 23.8 3.8e-07 29.7 0.4 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO18140.1 - 0.00011 20.4 0.2 0.0061 14.7 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 B_lectin PF01453.19 ETO18140.1 - 0.055 13.3 0.7 0.98 9.3 0.1 2.5 2 1 0 2 2 2 0 D-mannose binding lectin DUF4394 PF14339.1 ETO18140.1 - 0.073 12.3 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4394) Nucleoporin_N PF08801.6 ETO18140.1 - 0.093 11.4 2.5 0.25 10.0 0.6 2.3 1 1 0 1 1 1 0 Nup133 N terminal like Cucumo_coat PF00760.13 ETO18141.1 - 0.23 10.4 1.2 0.37 9.7 0.1 1.8 2 0 0 2 2 2 0 Cucumovirus coat protein UB2H PF14814.1 ETO18143.1 - 0.01 15.5 0.0 0.026 14.2 0.0 1.7 1 0 0 1 1 1 0 Bifunctional transglycosylase second domain RD3 PF14473.1 ETO18143.1 - 0.069 12.6 4.2 0.099 12.1 2.6 1.5 1 1 0 1 1 1 0 RD3 protein SNARE_assoc PF09335.6 ETO18144.1 - 3.8e-07 30.3 1.3 0.003 17.7 0.1 2.5 2 1 0 2 2 2 2 SNARE associated Golgi protein MRL1 PF13003.2 ETO18144.1 - 4.2 7.1 12.0 0.07 12.9 2.3 2.3 3 0 0 3 3 3 0 Ribosomal protein L1 DUF4392 PF14336.1 ETO18145.1 - 4.7e-15 55.1 0.1 5.6e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) DUF3287 PF11690.3 ETO18146.1 - 0.0041 17.1 0.2 0.007 16.4 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3287) VIT1 PF01988.14 ETO18146.1 - 0.074 12.5 0.2 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 VIT family G-alpha PF00503.15 ETO18147.1 - 1.8e-20 72.9 15.7 2e-19 69.5 10.8 2.5 1 1 0 1 1 1 1 G-protein alpha subunit DUF755 PF05501.6 ETO18147.1 - 0.02 14.9 6.1 0.02 14.9 4.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Ribosomal_60s PF00428.14 ETO18148.1 - 9.2 6.7 19.5 11 6.5 2.8 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein IL12 PF03039.9 ETO18149.1 - 0.0057 15.7 0.3 0.0064 15.6 0.2 1.0 1 0 0 1 1 1 1 Interleukin-12 alpha subunit Integrin_B_tail PF07965.7 ETO18149.1 - 0.28 11.6 2.3 2.5 8.6 0.7 2.1 1 1 1 2 2 2 0 Integrin beta tail domain Baculo_PP31 PF05311.6 ETO18150.1 - 0.0024 17.2 0.8 0.0024 17.2 0.6 1.7 2 0 0 2 2 2 1 Baculovirus 33KDa late protein (PP31) RRP14 PF15459.1 ETO18150.1 - 3.1 7.9 7.5 11 6.1 0.2 2.3 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 Arm PF00514.18 ETO18151.1 - 0.00021 20.9 0.2 1.7 8.6 0.0 5.1 5 1 0 5 5 5 2 Armadillo/beta-catenin-like repeat DUF3361 PF11841.3 ETO18151.1 - 0.033 13.9 0.1 2.1 8.0 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) GAS PF13851.1 ETO18152.1 - 2.4e-32 111.7 36.6 2.4e-32 111.7 25.4 2.9 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding DUF2433 PF10360.4 ETO18152.1 - 0.089 13.1 0.4 0.089 13.1 0.2 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2433) TAP_C PF03943.8 ETO18152.1 - 0.093 12.1 0.8 4.9 6.6 0.1 2.6 2 0 0 2 2 2 0 TAP C-terminal domain Sigma54_activ_2 PF14532.1 ETO18152.1 - 4.4 7.3 11.2 1.6 8.7 0.7 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain HR1 PF02185.11 ETO18153.1 - 0.066 12.9 5.7 0.14 11.9 3.7 1.8 1 1 0 1 1 1 0 Hr1 repeat TPR_MLP1_2 PF07926.7 ETO18153.1 - 0.21 11.3 10.6 0.33 10.6 7.3 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.5 ETO18153.1 - 0.23 11.5 6.6 0.087 12.9 2.4 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family LsmAD PF06741.8 ETO18153.1 - 0.46 10.6 4.2 0.38 10.8 1.4 2.0 1 1 1 2 2 2 0 LsmAD domain DUF342 PF03961.8 ETO18154.1 - 1.3 7.3 16.4 0.082 11.3 4.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) MIF4G_like_2 PF09090.6 ETO18154.1 - 1.3 8.1 14.4 0.026 13.7 3.8 2.0 1 1 0 2 2 2 0 MIF4G like Lectin_N PF03954.9 ETO18154.1 - 2.5 7.4 14.4 67 2.8 0.4 3.3 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF972 PF06156.8 ETO18154.1 - 2.9 8.2 19.8 7.8 6.8 4.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Imm23 PF15593.1 ETO18154.1 - 3.2 7.9 9.6 0.75 10.0 0.8 2.2 2 0 0 2 2 2 0 Immunity protein 23 ACCA PF03255.9 ETO18154.1 - 7.2 6.1 12.6 0.48 9.9 2.6 2.7 2 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Atg14 PF10186.4 ETO18154.1 - 8.3 5.2 26.6 0.35 9.7 10.0 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1759 PF03564.10 ETO18154.1 - 9.3 6.0 17.3 4.1 7.2 1.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1759) Bromodomain PF00439.20 ETO18155.1 - 3.1e-20 71.8 0.0 5.2e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Bromodomain LMBR1 PF04791.11 ETO18155.1 - 0.0053 15.3 0.2 0.0061 15.1 0.2 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein Zip PF02535.17 ETO18155.1 - 0.0062 15.5 0.1 0.0082 15.1 0.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Pex14_N PF04695.8 ETO18155.1 - 0.018 15.0 3.4 0.026 14.5 2.4 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CDC45 PF02724.9 ETO18155.1 - 0.067 11.2 7.6 0.086 10.8 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Suf PF05843.9 ETO18155.1 - 0.11 12.1 7.5 0.15 11.7 5.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4638 PF15472.1 ETO18155.1 - 0.21 11.1 12.2 0.31 10.6 8.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) RP-C_C PF11800.3 ETO18155.1 - 0.25 10.9 9.6 0.36 10.5 6.7 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Borrelia_P83 PF05262.6 ETO18155.1 - 0.57 8.3 12.7 0.71 8.0 8.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2215 PF10225.4 ETO18155.1 - 0.89 8.9 5.9 1.2 8.4 4.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) AIF_C PF14721.1 ETO18155.1 - 1.2 9.3 6.0 2.7 8.2 4.2 1.7 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Paramyxo_ncap PF00973.14 ETO18155.1 - 7 5.2 9.1 9 4.8 6.3 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DDHD PF02862.12 ETO18155.1 - 9.7 5.9 9.8 13 5.4 6.8 1.2 1 0 0 1 1 1 0 DDHD domain Raftlin PF15250.1 ETO18157.1 - 0.25 9.7 10.2 0.31 9.5 7.1 1.1 1 0 0 1 1 1 0 Raftlin MIP-T3 PF10243.4 ETO18157.1 - 0.66 8.3 27.3 0.75 8.1 18.9 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DDHD PF02862.12 ETO18157.1 - 0.68 9.6 14.5 0.99 9.1 10.0 1.3 1 0 0 1 1 1 0 DDHD domain GAGA_bind PF06217.7 ETO18157.1 - 0.71 9.7 12.6 0.87 9.4 8.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RRN3 PF05327.6 ETO18157.1 - 0.78 7.7 10.2 0.88 7.5 7.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Zip PF02535.17 ETO18157.1 - 0.94 8.4 7.5 1.1 8.1 5.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter FLO_LFY PF01698.11 ETO18157.1 - 1 8.1 14.8 1.3 7.8 10.3 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein TRAP_alpha PF03896.11 ETO18157.1 - 1.2 8.1 8.5 1.2 8.0 5.9 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2413 PF10310.4 ETO18157.1 - 1.3 7.7 25.4 1.6 7.4 17.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) CDC45 PF02724.9 ETO18157.1 - 1.7 6.6 20.3 2 6.3 14.1 1.1 1 0 0 1 1 1 0 CDC45-like protein CBP4 PF07960.6 ETO18157.1 - 1.9 8.1 15.4 8.3 6.0 0.0 2.3 2 0 0 2 2 2 0 CBP4 Atrophin-1 PF03154.10 ETO18157.1 - 2 6.4 13.2 2 6.4 9.2 1.2 1 0 0 1 1 1 0 Atrophin-1 family Transformer PF06495.6 ETO18157.1 - 2.2 8.1 6.6 12 5.7 3.0 2.0 1 1 1 2 2 2 0 Fruit fly transformer protein SprA-related PF12118.3 ETO18157.1 - 2.2 7.5 19.6 2.6 7.2 13.6 1.1 1 0 0 1 1 1 0 SprA-related family DUF4512 PF14975.1 ETO18157.1 - 3 8.7 9.4 13 6.7 6.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4512) PPP4R2 PF09184.6 ETO18157.1 - 5.5 6.4 24.0 7.2 6.0 16.6 1.1 1 0 0 1 1 1 0 PPP4R2 Cytomega_UL84 PF06284.6 ETO18157.1 - 7.2 4.8 8.3 7.3 4.8 5.8 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein TFIIA PF03153.8 ETO18158.1 - 0.23 11.2 11.4 0.26 11.1 7.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF912 PF06024.7 ETO18158.1 - 2.8 8.0 10.1 0.64 10.0 4.3 1.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) MFMR PF07777.6 ETO18158.1 - 4.1 7.2 12.8 5.6 6.8 8.9 1.2 1 0 0 1 1 1 0 G-box binding protein MFMR FGF PF00167.13 ETO18159.1 - 1.4e-05 24.8 2.0 0.092 12.5 0.1 2.9 2 1 1 3 3 3 3 Fibroblast growth factor Lipoprotein_18 PF06804.6 ETO18159.1 - 0.00031 19.5 0.9 0.0005 18.9 0.6 1.3 1 0 0 1 1 1 1 NlpB/DapX lipoprotein AbfB PF05270.8 ETO18159.1 - 0.0023 17.6 0.1 0.14 11.9 0.0 2.7 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase B (ABFB) RicinB_lectin_2 PF14200.1 ETO18159.1 - 0.0086 16.4 4.5 0.031 14.6 0.1 3.3 2 1 1 3 3 3 1 Ricin-type beta-trefoil lectin domain-like Fascin PF06268.8 ETO18159.1 - 0.036 14.1 0.2 3.9 7.6 0.0 3.0 2 1 1 3 3 3 0 Fascin domain TerD PF02342.13 ETO18159.1 - 0.038 13.3 0.4 0.056 12.7 0.3 1.3 1 0 0 1 1 1 0 TerD domain PCI PF01399.22 ETO18160.1 - 1.1e-06 28.9 0.3 2.2e-06 27.9 0.2 1.6 1 0 0 1 1 1 1 PCI domain ATP-synt_G PF04718.10 ETO18160.1 - 0.039 14.5 0.4 0.14 12.8 0.1 2.0 2 0 0 2 2 2 0 Mitochondrial ATP synthase g subunit TPR_19 PF14559.1 ETO18160.1 - 0.13 12.5 0.2 0.13 12.5 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Pex14_N PF04695.8 ETO18161.1 - 5.1e-05 23.3 0.6 9.5e-05 22.4 0.4 1.4 1 1 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Methyltransf_31 PF13847.1 ETO18161.1 - 0.27 10.8 1.8 0.48 9.9 0.1 2.0 1 1 1 2 2 2 0 Methyltransferase domain DcpS_C PF11969.3 ETO18161.1 - 0.6 10.3 3.6 0.26 11.5 0.7 1.8 2 0 0 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding EF-hand_8 PF13833.1 ETO18162.1 - 5.2e-08 32.3 0.1 1.9e-05 24.1 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.1 ETO18162.1 - 1.2e-07 31.6 0.0 3.2e-07 30.3 0.0 1.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO18162.1 - 2.1e-07 29.7 0.1 0.02 14.1 0.0 2.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 ETO18162.1 - 1.5e-05 24.4 0.2 0.088 12.7 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 ETO18162.1 - 0.02 14.2 0.2 2 7.9 0.0 2.4 2 0 0 2 2 2 0 EF hand EF-hand_4 PF12763.2 ETO18162.1 - 0.059 13.1 0.1 3.2 7.5 0.0 2.1 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand UPF0158 PF03682.8 ETO18162.1 - 0.068 12.7 0.0 0.081 12.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) Kelch_6 PF13964.1 ETO18163.1 - 3.1e-10 39.7 0.5 4.1e-05 23.5 0.0 3.9 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 ETO18163.1 - 1.6e-08 33.9 0.8 0.0028 17.1 0.1 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 ETO18163.1 - 0.03 14.4 0.5 0.9 9.7 0.0 3.1 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO18163.1 - 0.083 12.6 1.7 7.6 6.4 0.6 3.3 3 1 0 3 3 3 0 Kelch motif RelA_SpoT PF04607.12 ETO18164.1 - 0.0018 18.2 0.2 0.007 16.3 0.2 2.0 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins MRP-S32 PF10210.4 ETO18164.1 - 0.078 13.2 1.1 0.48 10.7 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S32 Syntaxin_2 PF14523.1 ETO18164.1 - 0.36 10.8 7.5 3.3 7.7 0.1 3.9 3 1 0 3 3 3 0 Syntaxin-like protein Na_Ca_ex PF01699.19 ETO18165.1 - 0.095 12.2 9.6 0.91 9.1 3.1 2.2 1 1 1 2 2 2 0 Sodium/calcium exchanger protein GspL_C PF12693.2 ETO18165.1 - 0.58 9.9 2.3 4 7.1 0.1 2.8 3 0 0 3 3 3 0 GspL periplasmic domain TctB PF07331.6 ETO18165.1 - 1 9.0 10.7 2.3 7.8 3.9 2.7 1 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family PrgI PF12666.2 ETO18165.1 - 1.3 9.2 9.1 11 6.3 0.2 2.8 2 1 0 2 2 2 0 PrgI family protein COX4_pro PF03626.9 ETO18165.1 - 2.9 8.0 15.2 0.074 13.1 1.0 3.4 3 1 0 3 3 3 0 Prokaryotic Cytochrome C oxidase subunit IV DUF4181 PF13789.1 ETO18165.1 - 5.9 6.8 9.0 0.55 10.1 2.6 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4181) Glycos_transf_4 PF00953.16 ETO18165.1 - 6.4 6.5 9.1 0.52 10.0 1.8 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 4 CTP_transf_1 PF01148.15 ETO18165.1 - 10 5.7 14.0 1.6 8.3 4.5 2.1 1 1 1 2 2 2 0 Cytidylyltransferase family CTDII PF01556.13 ETO18167.1 - 1.1e-09 38.0 0.2 9.9e-09 34.9 0.1 2.3 2 0 0 2 2 2 1 DnaJ C terminal domain PTRF_SDPR PF15237.1 ETO18167.1 - 0.0031 16.9 6.7 0.0039 16.6 4.7 1.1 1 0 0 1 1 1 1 PTRF/SDPR family ArfGap PF01412.13 ETO18167.1 - 0.089 12.5 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf BLVR PF06375.6 ETO18167.1 - 0.099 12.4 9.0 0.13 12.0 6.2 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) BAF1_ABF1 PF04684.8 ETO18168.1 - 0.043 12.6 8.9 0.053 12.3 6.2 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CagX PF03524.10 ETO18168.1 - 0.11 11.7 0.8 0.15 11.3 0.6 1.3 1 0 0 1 1 1 0 Conjugal transfer protein Maf1 PF09174.5 ETO18168.1 - 0.16 11.8 3.4 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 Maf1 regulator TMEM51 PF15345.1 ETO18168.1 - 1.5 8.4 8.3 2 8.0 5.7 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 PAT1 PF09770.4 ETO18168.1 - 2 6.5 26.0 2.4 6.3 18.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RseA_N PF03872.8 ETO18168.1 - 4.4 7.6 9.2 7.1 7.0 6.4 1.3 1 0 0 1 1 1 0 Anti sigma-E protein RseA, N-terminal domain Ras PF00071.17 ETO18169.1 - 5.1e-07 29.2 0.0 8.8e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 ETO18169.1 - 0.02 14.1 0.0 0.046 12.9 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Miro PF08477.8 ETO18169.1 - 0.023 15.2 0.1 0.056 13.9 0.0 1.7 2 0 0 2 2 2 0 Miro-like protein NPR3 PF03666.8 ETO18169.1 - 0.22 10.0 10.7 1.2 7.5 4.8 2.2 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Secretin_N_2 PF07655.8 ETO18171.1 - 4 7.8 7.0 0.45 10.9 0.6 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain Cullin PF00888.17 ETO18172.1 - 1.1e-63 215.6 2.9 1.5e-63 215.3 2.0 1.0 1 0 0 1 1 1 1 Cullin family SF3a60_bindingd PF12108.3 ETO18172.1 - 0.043 13.3 0.2 1.8 8.1 0.1 2.6 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain DUF3398 PF11878.3 ETO18173.1 - 0.0062 16.3 0.1 0.019 14.8 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3398) NYD-SP28 PF14772.1 ETO18173.1 - 0.015 15.3 2.9 0.03 14.4 2.0 1.5 1 0 0 1 1 1 0 Sperm tail ACR_tran PF00873.14 ETO18173.1 - 0.017 12.5 0.4 0.026 11.9 0.3 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family DUF2693 PF10902.3 ETO18173.1 - 0.1 12.4 0.4 0.35 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2693) BMP2K_C PF15282.1 ETO18173.1 - 0.86 9.7 9.6 2.4 8.2 6.3 1.9 1 1 1 2 2 2 0 BMP-2-inducible protein kinase C-terminus SSFA2_C PF14723.1 ETO18174.1 - 0.0025 17.5 6.2 0.0034 17.1 4.3 1.2 1 0 0 1 1 1 1 Sperm-specific antigen 2 C-terminus SufE PF02657.10 ETO18174.1 - 0.016 14.8 0.3 0.029 14.0 0.2 1.6 1 1 0 1 1 1 0 Fe-S metabolism associated domain DNA_pol3_beta PF00712.14 ETO18174.1 - 0.075 12.9 2.0 0.097 12.5 0.5 1.8 1 1 1 2 2 2 0 DNA polymerase III beta subunit, N-terminal domain ABC2_membrane_3 PF12698.2 ETO18174.1 - 0.098 11.6 2.0 0.12 11.3 1.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4469 PF14734.1 ETO18174.1 - 0.11 12.4 0.1 0.29 11.0 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4469) with IG-like fold DUF2344 PF10105.4 ETO18174.1 - 0.36 10.3 6.2 0.6 9.5 4.3 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) DUF3482 PF11981.3 ETO18174.1 - 0.41 9.8 4.6 0.45 9.7 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Lectin_N PF03954.9 ETO18174.1 - 0.46 9.8 3.5 0.24 10.7 0.8 1.7 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain IFT20 PF14931.1 ETO18174.1 - 2.1 8.2 15.2 0.21 11.5 7.1 1.8 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Atg14 PF10186.4 ETO18174.1 - 5.2 5.9 12.8 6 5.7 8.8 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 ETO18174.1 - 5.6 5.9 13.6 7.7 5.4 9.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 VIT1 PF01988.14 ETO18174.1 - 8 5.8 6.5 13 5.2 4.5 1.4 1 1 0 1 1 1 0 VIT family PUF PF00806.14 ETO18177.1 - 4.4e-06 25.8 0.2 0.05 13.0 0.1 2.7 2 0 0 2 2 2 2 Pumilio-family RNA binding repeat DUF4391 PF14335.1 ETO18177.1 - 0.0062 15.9 5.3 0.0094 15.3 3.4 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4391) DUF2430 PF10353.4 ETO18177.1 - 0.078 13.1 0.2 0.22 11.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2430) AAA PF00004.24 ETO18178.1 - 0.017 15.3 0.2 0.035 14.3 0.1 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 ETO18178.1 - 0.044 13.6 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNB PF00773.14 ETO18181.1 - 6e-18 65.1 0.1 1.9e-17 63.5 0.0 1.8 2 1 1 3 3 3 1 RNB domain WD40 PF00400.27 ETO18183.1 - 1.2e-36 123.2 10.1 9.6e-08 31.6 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 ETO18183.1 - 7.5e-29 99.4 0.5 1.6e-28 98.4 0.4 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex 2-oxoacid_dh PF00198.18 ETO18186.1 - 9.1e-47 159.2 0.0 1.1e-46 158.9 0.0 1.0 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Rod_cone_degen PF15201.1 ETO18188.1 - 5.3 6.9 5.5 0.76 9.6 0.1 2.3 2 0 0 2 2 2 0 Progressive rod-cone degeneration DUF3897 PF13036.1 ETO18189.1 - 0.007 15.9 0.1 0.015 14.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3897) OATP PF03137.15 ETO18190.1 - 0.12 10.4 4.8 1.4 6.8 0.2 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF912 PF06024.7 ETO18190.1 - 3.3 7.8 8.8 0.33 11.0 1.2 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) GHMP_kinases_N PF00288.21 ETO18192.1 - 5.4e-05 23.1 0.0 0.00015 21.7 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain Cortex-I_coil PF09304.5 ETO18192.1 - 0.00098 19.1 0.1 0.00098 19.1 0.1 2.0 2 0 0 2 2 2 1 Cortexillin I, coiled coil Pox_E8 PF03394.8 ETO18192.1 - 0.0047 16.3 2.2 0.01 15.2 1.5 1.6 1 0 0 1 1 1 1 Poxvirus E8 protein GalKase_gal_bdg PF10509.4 ETO18192.1 - 0.058 12.6 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 ETO18192.1 - 0.17 12.1 0.2 0.5 10.5 0.2 1.8 1 0 0 1 1 1 0 GHMP kinases C terminal Sulfotransfer_3 PF13469.1 ETO18194.1 - 0.011 16.7 0.1 0.099 13.5 0.0 2.4 2 1 0 2 2 2 0 Sulfotransferase family zf-DNA_Pol PF08996.5 ETO18194.1 - 2.7 7.2 7.6 3.5 6.9 0.1 3.1 3 0 0 3 3 3 0 DNA Polymerase alpha zinc finger ANAPC15 PF15243.1 ETO18195.1 - 0.013 15.5 2.8 0.013 15.5 1.9 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 15 Pkinase PF00069.20 ETO18198.1 - 4.1e-19 68.7 5.5 3.3e-18 65.7 3.8 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO18198.1 - 1e-08 34.5 4.1 6.9e-08 31.8 2.8 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETO18198.1 - 3.8e-05 23.5 0.0 0.00064 19.5 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 ETO18198.1 - 0.052 12.5 0.0 0.099 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LeuA_dimer PF08502.5 ETO18198.1 - 0.076 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 LeuA allosteric (dimerisation) domain CPG4 PF15481.1 ETO18200.1 - 1.3 9.4 9.2 0.71 10.2 4.1 2.2 2 0 0 2 2 2 0 Chondroitin proteoglycan 4 Ribosomal_60s PF00428.14 ETO18201.1 - 0.045 14.1 0.9 0.087 13.2 0.6 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein zf-BED PF02892.10 ETO18202.1 - 0.18 11.5 0.2 0.18 11.5 0.1 3.4 3 0 0 3 3 3 0 BED zinc finger zf-HC5HC2H_2 PF13832.1 ETO18202.1 - 1.9 8.5 10.9 0.29 11.1 3.2 2.6 2 2 0 2 2 2 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 ETO18202.1 - 8.3 6.6 11.0 0.47 10.6 2.3 2.7 2 2 0 2 2 2 0 PHD-like zinc-binding domain G-alpha PF00503.15 ETO18203.1 - 1.9e-24 86.0 3.2 2.4e-24 85.7 2.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit PRK PF00485.13 ETO18203.1 - 1.6e-05 24.5 0.2 2.6e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.10 ETO18203.1 - 0.00028 19.6 0.1 0.00042 19.1 0.0 1.4 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 ETO18203.1 - 0.00075 20.3 0.1 0.005 17.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.1 ETO18203.1 - 0.0011 19.0 1.0 0.0018 18.3 0.6 1.3 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 ETO18203.1 - 0.0029 17.8 1.3 0.0056 16.9 0.9 1.6 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 ETO18203.1 - 0.006 16.0 0.1 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Imm-NTF2 PF15655.1 ETO18203.1 - 0.027 14.9 0.7 0.027 14.9 0.5 2.7 2 1 1 3 3 3 0 NTF2 fold immunity protein T2SE PF00437.15 ETO18203.1 - 0.035 13.0 0.1 0.057 12.3 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.9 ETO18203.1 - 0.037 13.7 0.1 0.12 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.8 ETO18203.1 - 0.042 12.7 0.1 0.071 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) VirE PF05272.6 ETO18203.1 - 0.05 13.0 1.2 0.096 12.1 0.9 1.5 1 0 0 1 1 1 0 Virulence-associated protein E AAA PF00004.24 ETO18203.1 - 0.061 13.5 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 ETO18203.1 - 0.065 12.7 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Peptidase_S48 PF03574.10 ETO18203.1 - 0.079 12.9 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Peptidase family S48 Zeta_toxin PF06414.7 ETO18203.1 - 0.086 11.9 2.2 0.18 10.9 0.2 2.2 2 1 0 2 2 2 0 Zeta toxin AAA_16 PF13191.1 ETO18203.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 ETO18203.1 - 0.12 12.5 0.2 0.29 11.2 0.1 1.8 1 1 1 2 2 2 0 AAA domain MCM PF00493.18 ETO18203.1 - 0.54 8.9 4.7 0.74 8.5 0.1 2.2 1 1 1 2 2 2 0 MCM2/3/5 family AAA_23 PF13476.1 ETO18203.1 - 1.7 8.8 10.1 1.7 8.9 6.3 1.7 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.15 ETO18204.1 - 1e-29 103.4 8.8 1.7e-29 102.7 6.1 1.3 1 1 0 1 1 1 1 G-protein alpha subunit PYST-C1 PF09690.5 ETO18204.1 - 0.08 12.5 0.3 0.15 11.6 0.2 1.5 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) FH2 PF02181.18 ETO18205.1 - 5.2e-08 32.1 2.6 1.5e-07 30.6 1.8 1.8 1 1 0 1 1 1 1 Formin Homology 2 Domain RRM_1 PF00076.17 ETO18206.1 - 5.5e-36 122.0 0.1 8.4e-16 57.3 0.0 4.4 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO18206.1 - 1.2e-22 79.6 0.0 3.2e-09 36.6 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO18206.1 - 1.8e-21 75.7 0.1 4.5e-07 29.6 0.0 4.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NST1 PF13945.1 ETO18206.1 - 0.28 11.2 6.0 8.7 6.3 1.6 2.6 2 0 0 2 2 2 0 Salt tolerance down-regulator Transformer PF06495.6 ETO18206.1 - 0.39 10.5 9.6 0.95 9.3 6.7 1.6 1 0 0 1 1 1 0 Fruit fly transformer protein Pex14_N PF04695.8 ETO18206.1 - 4.4 7.3 14.9 16 5.5 0.4 3.9 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TUG-UBL1 PF11470.3 ETO18207.1 - 0.083 12.8 0.3 0.18 11.7 0.2 1.6 1 0 0 1 1 1 0 GLUT4 regulating protein TUG DUF2924 PF11149.3 ETO18207.1 - 0.18 11.8 1.1 0.41 10.6 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) FlxA PF14282.1 ETO18207.1 - 1.6 8.7 13.7 0.1 12.5 0.9 2.8 3 0 0 3 3 3 0 FlxA-like protein DUF106 PF01956.11 ETO18207.1 - 2.3 7.7 6.0 11 5.5 0.1 2.1 2 0 0 2 2 2 0 Integral membrane protein DUF106 RGS PF00615.14 ETO18210.1 - 0.015 15.3 0.6 0.019 15.0 0.4 1.4 1 1 0 1 1 1 0 Regulator of G protein signaling domain G-alpha PF00503.15 ETO18211.1 - 0.016 13.9 1.3 0.02 13.6 0.9 1.1 1 0 0 1 1 1 0 G-protein alpha subunit EpsG PF14897.1 ETO18212.1 - 0.018 14.0 1.6 0.023 13.6 1.1 1.1 1 0 0 1 1 1 0 EpsG family Potyvirid-P3 PF13608.1 ETO18212.1 - 0.034 13.2 2.1 0.04 13.0 1.4 1.2 1 1 0 1 1 1 0 Protein P3 of Potyviral polyprotein Phage_Gp23 PF10669.4 ETO18212.1 - 0.096 12.8 6.6 0.089 12.9 3.9 1.4 1 1 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DHC_N2 PF08393.8 ETO18214.1 - 9.5e-22 77.0 0.3 1.1e-21 76.8 0.2 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 WD40 PF00400.27 ETO18215.1 - 3.5e-71 232.7 23.0 5.3e-12 45.1 0.0 7.5 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO18215.1 - 5.7e-08 31.3 9.0 0.057 11.5 0.1 4.8 1 1 5 6 6 6 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO18215.1 - 7.8e-08 30.9 0.3 0.088 11.0 0.0 3.1 1 1 1 3 3 3 3 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO18215.1 - 8.6e-06 25.3 1.8 0.00018 21.0 1.4 2.3 1 1 0 1 1 1 1 PQQ-like domain PD40 PF07676.7 ETO18215.1 - 1.9e-05 24.2 13.6 4.7 6.9 0.0 6.6 7 0 0 7 7 7 3 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO18215.1 - 4.3e-05 23.6 0.0 0.86 9.9 0.0 4.8 2 1 2 5 5 5 1 Resistin DUF1258 PF06869.7 ETO18215.1 - 0.00096 18.3 4.7 0.37 9.8 0.0 3.8 2 2 2 4 4 4 2 Protein of unknown function (DUF1258) Gmad1 PF10647.4 ETO18215.1 - 0.0013 18.2 0.1 0.096 12.0 0.0 2.6 2 1 1 3 3 3 1 Lipoprotein LpqB beta-propeller domain DUF1652 PF07865.6 ETO18215.1 - 0.02 14.4 0.0 6.8 6.3 0.0 3.8 5 0 0 5 5 5 0 Protein of unknown function (DUF1652) DUF2850 PF11012.3 ETO18215.1 - 0.06 13.5 0.0 0.34 11.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2850) NACHT PF05729.7 ETO18216.1 - 1.3e-16 60.7 0.0 5.9e-16 58.5 0.0 2.1 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 ETO18216.1 - 1.1e-07 31.0 2.8 1.1e-07 31.0 2.0 1.9 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.1 ETO18216.1 - 0.00023 21.2 0.0 0.00069 19.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 ETO18216.1 - 0.001 19.2 0.2 0.0051 16.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain DUF87 PF01935.12 ETO18216.1 - 0.018 14.9 0.2 0.14 11.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 Nup35_RRM_2 PF14605.1 ETO18216.1 - 0.03 14.0 0.0 0.079 12.7 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif AFG1_ATPase PF03969.11 ETO18216.1 - 0.035 12.9 0.0 0.066 12.0 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase MEF2_binding PF09047.5 ETO18216.1 - 0.18 11.4 0.9 0.5 10.0 0.6 1.7 1 0 0 1 1 1 0 MEF2 binding GTP_EFTU PF00009.22 ETO18216.1 - 0.34 10.3 0.0 0.34 10.3 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 ETO18216.1 - 0.39 11.0 2.8 0.48 10.7 0.1 2.4 2 1 0 2 2 2 0 ABC transporter RNA_helicase PF00910.17 ETO18216.1 - 0.8 9.9 0.0 0.8 9.9 0.0 3.0 4 0 0 4 4 4 0 RNA helicase UPRTase PF14681.1 ETO18218.1 - 6.4e-07 28.7 0.0 9.6e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase U79_P34 PF03064.11 ETO18218.1 - 9.5e-05 22.0 18.6 0.00012 21.7 12.9 1.1 1 0 0 1 1 1 1 HSV U79 / HCMV P34 Hid1 PF12722.2 ETO18218.1 - 0.63 7.6 16.0 0.62 7.6 11.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ycf1 PF05758.7 ETO18218.1 - 2.4 5.7 17.9 2.5 5.7 12.4 1.1 1 0 0 1 1 1 0 Ycf1 SID-1_RNA_chan PF13965.1 ETO18218.1 - 3.2 5.7 4.5 3.6 5.6 3.1 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Cellulose_synt PF03552.9 ETO18218.1 - 4.9 5.3 5.1 5.6 5.1 3.5 1.2 1 0 0 1 1 1 0 Cellulose synthase Ank PF00023.25 ETO18219.1 - 0.011 15.4 0.0 0.03 14.1 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat Ank_3 PF13606.1 ETO18219.1 - 0.015 15.4 0.0 0.059 13.6 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeat Ank_2 PF12796.2 ETO18219.1 - 0.043 14.1 0.1 0.088 13.1 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) RbcS PF12338.3 ETO18220.1 - 0.011 15.5 5.4 0.011 15.5 3.8 2.5 1 1 1 2 2 2 0 Ribulose-1,5-bisphosphate carboxylase small subunit Glyco_tran_WbsX PF14307.1 ETO18221.1 - 0.031 13.4 0.5 0.057 12.5 0.1 1.6 1 1 0 1 1 1 0 Glycosyltransferase WbsX DUF87 PF01935.12 ETO18221.1 - 0.099 12.4 0.7 0.21 11.3 0.1 1.8 2 1 0 2 2 2 0 Domain of unknown function DUF87 Kei1 PF08552.6 ETO18221.1 - 4.4 6.9 6.7 1.6 8.3 0.6 2.1 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 TRAM_LAG1_CLN8 PF03798.11 ETO18222.1 - 1.1e-08 34.8 28.8 1.1e-08 34.8 20.0 1.5 2 0 0 2 2 2 1 TLC domain CHCH PF06747.8 ETO18222.1 - 0.23 11.4 8.2 0.099 12.5 3.5 2.2 2 0 0 2 2 2 0 CHCH domain AOX PF01786.12 ETO18223.1 - 2.2e-68 229.7 0.6 2.8e-68 229.4 0.4 1.1 1 0 0 1 1 1 1 Alternative oxidase DUF2628 PF10947.3 ETO18224.1 - 0.0061 16.3 0.1 0.014 15.2 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2628) RNHCP PF12647.2 ETO18224.1 - 0.066 13.0 3.3 0.066 13.0 1.0 2.0 2 0 0 2 2 2 0 RNHCP domain SDA1 PF05285.7 ETO18224.1 - 0.2 10.9 13.5 0.29 10.3 9.4 1.2 1 0 0 1 1 1 0 SDA1 CPG4 PF15481.1 ETO18225.1 - 0.0049 17.1 0.2 0.0092 16.3 0.1 1.5 1 0 0 1 1 1 1 Chondroitin proteoglycan 4 Lipoprotein_1 PF00820.14 ETO18225.1 - 0.017 14.2 0.6 0.026 13.6 0.4 1.3 1 0 0 1 1 1 0 Borrelia lipoprotein TFIIS_C PF01096.13 ETO18226.1 - 6e-09 35.3 3.8 5.6e-07 29.0 0.0 3.0 3 0 0 3 3 3 2 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 ETO18226.1 - 2.3e-06 27.1 6.9 2.3e-06 27.1 4.8 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1 PF03811.8 ETO18226.1 - 0.0028 17.0 2.0 0.018 14.5 0.1 2.3 2 0 0 2 2 2 1 InsA N-terminal domain DZR PF12773.2 ETO18226.1 - 0.0046 16.7 4.9 0.056 13.2 1.4 2.3 2 0 0 2 2 2 1 Double zinc ribbon Ribosomal_S27e PF01667.12 ETO18226.1 - 0.016 14.7 0.4 0.016 14.7 0.3 2.7 2 1 0 2 2 2 0 Ribosomal protein S27 Zn_Tnp_IS1595 PF12760.2 ETO18226.1 - 0.02 14.6 2.3 1.8 8.4 0.0 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_5 PF13719.1 ETO18226.1 - 0.062 12.8 7.3 0.6 9.7 0.1 2.8 2 1 0 2 2 2 0 zinc-ribbon domain Lar_restr_allev PF14354.1 ETO18226.1 - 0.075 13.3 2.6 6 7.2 0.0 2.3 2 0 0 2 2 2 0 Restriction alleviation protein Lar Mcm10 PF09332.6 ETO18226.1 - 0.092 12.0 2.0 0.15 11.3 1.4 1.3 1 0 0 1 1 1 0 Mcm10 replication factor C1_1 PF00130.17 ETO18226.1 - 0.14 11.9 4.6 0.058 13.1 1.0 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Yippee-Mis18 PF03226.9 ETO18226.1 - 0.23 11.5 3.1 0.46 10.5 1.2 2.3 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_4 PF13717.1 ETO18226.1 - 0.32 10.7 9.1 0.57 9.9 0.2 3.0 2 1 0 2 2 2 0 zinc-ribbon domain C1_4 PF07975.7 ETO18226.1 - 0.49 10.4 5.9 1.7 8.7 2.0 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain zf-C4_Topoisom PF01396.14 ETO18226.1 - 0.65 9.5 10.7 5.4 6.6 0.3 3.4 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger zf-B_box PF00643.19 ETO18226.1 - 0.69 9.8 9.6 9.8 6.1 3.4 2.6 2 1 0 2 2 2 0 B-box zinc finger DUF3797 PF12677.2 ETO18226.1 - 1.7 8.3 7.4 3.4 7.3 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3797) HypA PF01155.14 ETO18226.1 - 5.2 6.7 7.4 56 3.4 5.0 2.2 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Wzy_C PF04932.10 ETO18227.1 - 0.2 11.4 12.6 0.21 11.3 8.7 1.2 1 0 0 1 1 1 0 O-Antigen ligase 7tm_7 PF08395.7 ETO18227.1 - 0.56 9.1 10.3 0.62 9.0 7.1 1.0 1 0 0 1 1 1 0 7tm Chemosensory receptor CbiQ PF02361.11 ETO18227.1 - 3.9 6.9 15.7 4.6 6.7 10.9 1.1 1 0 0 1 1 1 0 Cobalt transport protein DUF3043 PF11241.3 ETO18227.1 - 5.2 6.6 10.1 6.5 6.3 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) CobT PF06213.7 ETO18228.1 - 0.0059 15.7 10.1 0.0094 15.1 7.0 1.3 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT UPF0118 PF01594.11 ETO18228.1 - 0.053 12.4 0.2 0.072 12.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF20 RRN3 PF05327.6 ETO18228.1 - 0.28 9.2 4.9 0.37 8.8 3.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Neur_chan_memb PF02932.11 ETO18228.1 - 1.6 8.5 6.1 2.1 8.1 4.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2201_N PF13203.1 ETO18228.1 - 7.8 5.5 8.1 10 5.2 5.6 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain K1377 PF15352.1 ETO18229.1 - 0.0098 13.8 3.1 0.011 13.7 2.1 1.0 1 0 0 1 1 1 1 Susceptibility to monomelic amyotrophy Tubulin_2 PF13809.1 ETO18229.1 - 0.031 13.2 0.9 0.037 12.9 0.7 1.0 1 0 0 1 1 1 0 Tubulin like DUF4642 PF15484.1 ETO18229.1 - 0.096 12.6 2.7 0.11 12.4 1.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) YPEB PF14620.1 ETO18229.1 - 0.85 8.5 4.3 0.98 8.3 3.0 1.0 1 0 0 1 1 1 0 YpeB sporulation DUF3546 PF12066.3 ETO18230.1 - 0.0013 18.6 1.3 0.0021 18.0 0.9 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3546) Viral_cys_rich PF08008.7 ETO18231.1 - 0.073 12.6 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Viral cysteine rich DUF4199 PF13858.1 ETO18231.1 - 9.1 6.1 16.1 1.3 8.8 6.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) TPT PF03151.11 ETO18233.1 - 1.5e-08 34.4 28.0 1.8e-05 24.4 1.2 2.8 3 0 0 3 3 3 2 Triose-phosphate Transporter family EmrE PF13536.1 ETO18233.1 - 2.2e-08 34.2 0.1 2.2e-08 34.2 0.1 4.0 4 1 1 5 5 5 1 Multidrug resistance efflux transporter EamA PF00892.15 ETO18233.1 - 5.8e-08 32.8 41.1 7.1e-08 32.5 3.3 4.5 3 2 2 5 5 5 2 EamA-like transporter family Nuc_sug_transp PF04142.10 ETO18233.1 - 2.3e-07 30.1 7.5 1.2e-06 27.8 5.2 2.2 1 1 0 1 1 1 1 Nucleotide-sugar transporter DUF2956 PF11169.3 ETO18233.1 - 0.034 14.1 1.0 0.12 12.3 0.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) DUF914 PF06027.7 ETO18233.1 - 0.37 9.5 20.0 2 7.1 13.9 2.1 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) Cortexin PF11057.3 ETO18233.1 - 1.3 8.6 4.9 0.67 9.6 0.8 2.5 2 0 0 2 2 2 0 Cortexin of kidney Sec20 PF03908.8 ETO18234.1 - 0.00063 19.3 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 Sec20 WD40 PF00400.27 ETO18235.1 - 2e-54 179.6 29.6 1.6e-09 37.2 1.9 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO18235.1 - 1.1e-07 30.4 8.9 0.068 11.2 0.0 5.6 1 1 3 5 5 5 4 Nucleoporin Nup120/160 DUF1900 PF08954.6 ETO18235.1 - 0.0022 17.5 0.0 2 7.9 0.0 3.0 2 0 0 2 2 2 2 Domain of unknown function (DUF1900) WD40 PF00400.27 ETO18236.1 - 6.9e-65 212.7 30.0 5e-11 42.0 0.5 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO18236.1 - 3.8e-07 28.6 14.2 0.0025 16.0 0.6 5.5 1 1 3 6 6 6 6 Nucleoporin Nup120/160 DUF953 PF06110.6 ETO18237.1 - 1.9e-37 127.3 0.9 2.3e-37 127.0 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.1 ETO18237.1 - 0.16 11.5 1.0 0.25 10.9 0.7 1.5 1 1 0 1 1 1 0 Thioredoxin Zip PF02535.17 ETO18238.1 - 1.6 7.7 12.0 0.17 10.8 1.7 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter IFT43 PF15305.1 ETO18239.1 - 0.11 12.5 7.8 1.5 8.8 3.7 2.2 2 0 0 2 2 2 0 Intraflagellar transport protein 43 DUF2215 PF10225.4 ETO18239.1 - 0.6 9.5 4.1 1.3 8.4 2.7 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Kinesin PF00225.18 ETO18240.1 - 9.4e-30 103.4 0.7 9.4e-30 103.4 0.5 2.0 2 0 0 2 2 2 1 Kinesin motor domain Asp_protease PF09668.5 ETO18240.1 - 0.017 14.6 0.0 0.25 10.9 0.0 2.4 2 0 0 2 2 2 0 Aspartyl protease AAA_24 PF13479.1 ETO18240.1 - 0.024 14.2 0.0 0.024 14.2 0.0 2.3 3 1 1 4 4 4 0 AAA domain Kinesin PF00225.18 ETO18241.1 - 7.3e-48 162.9 1.0 7.3e-48 162.9 0.7 1.8 2 1 0 2 2 2 1 Kinesin motor domain bZIP_2 PF07716.10 ETO18241.1 - 0.2 11.4 18.2 0.037 13.8 3.2 3.0 2 1 0 2 2 2 0 Basic region leucine zipper PspB PF06667.7 ETO18241.1 - 1.3 9.0 4.0 21 5.1 1.0 3.5 3 1 0 3 3 3 0 Phage shock protein B NYD-SP28_assoc PF14775.1 ETO18241.1 - 4.4 7.0 8.1 0.46 10.2 1.0 2.5 2 0 0 2 2 2 0 Sperm tail C-terminal domain TPR_12 PF13424.1 ETO18242.1 - 2.1e-26 91.6 7.7 4.4e-09 36.1 0.3 3.7 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO18242.1 - 4.8e-10 38.9 7.5 4e-07 29.5 1.2 3.5 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 ETO18242.1 - 2.9e-08 32.9 17.4 0.0006 19.3 0.4 6.0 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO18242.1 - 7.8e-08 31.5 1.8 0.081 12.7 0.0 4.3 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO18242.1 - 1.3e-06 27.8 8.6 0.0013 18.4 0.3 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETO18242.1 - 1.3e-05 24.9 0.1 0.17 11.8 0.0 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO18242.1 - 3.2e-05 23.3 12.7 0.0086 15.7 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO18242.1 - 0.00035 20.5 2.5 2.7 8.4 0.0 4.0 2 1 1 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 ETO18242.1 - 0.004 17.0 2.0 0.1 12.5 0.1 3.5 2 1 1 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_14 PF13428.1 ETO18242.1 - 0.033 14.8 0.0 0.27 11.9 0.0 2.6 2 1 1 3 3 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETO18242.1 - 0.043 14.4 0.0 0.73 10.5 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO18242.1 - 0.12 12.8 1.4 2.1 9.0 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.7 ETO18242.1 - 0.17 12.5 1.8 13 6.5 0.1 3.1 3 0 0 3 3 2 0 Sel1 repeat Apc3 PF12895.2 ETO18242.1 - 0.28 11.3 3.7 0.94 9.6 1.2 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 CENP-T PF15511.1 ETO18243.1 - 0.00019 20.8 12.1 0.0002 20.7 8.4 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CDC45 PF02724.9 ETO18243.1 - 0.021 12.8 19.5 0.026 12.6 13.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 ETO18243.1 - 2.1 7.6 28.8 0.45 9.8 17.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Hid1 PF12722.2 ETO18243.1 - 4.2 4.9 16.8 5 4.6 11.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Menin PF05053.8 ETO18243.1 - 4.7 5.2 10.5 5.7 4.9 7.3 1.2 1 0 0 1 1 1 0 Menin BUD22 PF09073.5 ETO18243.1 - 9.4 5.1 34.4 12 4.8 23.5 1.3 1 1 0 1 1 1 0 BUD22 Fez1 PF06818.10 ETO18244.1 - 0.043 13.8 10.6 0.075 13.0 7.3 1.4 1 0 0 1 1 1 0 Fez1 OmpH PF03938.9 ETO18244.1 - 0.31 10.9 7.5 0.52 10.2 5.2 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Mnd1 PF03962.10 ETO18244.1 - 0.37 10.4 13.1 0.57 9.8 9.1 1.3 1 0 0 1 1 1 0 Mnd1 family APG6 PF04111.7 ETO18244.1 - 0.65 8.9 8.9 1 8.3 6.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1675 PF07897.6 ETO18244.1 - 0.9 9.3 13.5 1.2 8.9 9.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) LCD1 PF09798.4 ETO18244.1 - 1 7.2 12.3 5.6 4.8 6.2 2.0 2 0 0 2 2 2 0 DNA damage checkpoint protein BTV_NS2 PF04514.7 ETO18244.1 - 1.7 7.4 7.8 2.8 6.7 5.4 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 IncA PF04156.9 ETO18244.1 - 2.1 7.8 10.9 4.9 6.6 7.5 1.6 1 0 0 1 1 1 0 IncA protein FadA PF09403.5 ETO18244.1 - 2.3 8.2 10.0 5.9 6.9 7.0 1.7 1 0 0 1 1 1 0 Adhesion protein FadA V_ATPase_I PF01496.14 ETO18244.1 - 2.7 5.7 5.4 3.1 5.5 3.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4613 PF15390.1 ETO18244.1 - 3.5 5.6 8.1 4.3 5.3 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) PGA2 PF07543.7 ETO18246.1 - 0.34 10.7 1.8 16 5.2 0.2 2.1 2 0 0 2 2 2 0 Protein trafficking PGA2 UPF0370 PF13980.1 ETO18247.1 - 0.23 11.2 1.4 0.44 10.3 1.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) YMF19 PF02326.10 ETO18247.1 - 0.48 11.0 5.1 0.15 12.6 0.7 2.1 2 0 0 2 2 2 0 Plant ATP synthase F0 WBP-1 PF11669.3 ETO18247.1 - 2.8 8.0 5.4 0.9 9.6 0.7 2.2 2 1 0 2 2 2 0 WW domain-binding protein 1 SH3_1 PF00018.23 ETO18247.1 - 4.3 6.8 5.4 2 7.8 0.1 2.6 3 0 0 3 3 3 0 SH3 domain Alpha_kinase PF02816.13 ETO18248.1 - 1.4e-34 119.3 0.5 1.4e-34 119.3 0.3 2.3 3 1 0 3 3 3 1 Alpha-kinase family DUF913 PF06025.7 ETO18248.1 - 1 8.0 7.0 1.4 7.5 4.9 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RRN3 PF05327.6 ETO18248.1 - 1.9 6.5 11.2 2.7 5.9 7.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Daxx PF03344.10 ETO18248.1 - 1.9 6.8 23.3 2.4 6.5 16.2 1.2 1 0 0 1 1 1 0 Daxx Family TRAP_alpha PF03896.11 ETO18248.1 - 2.1 7.2 10.2 3.3 6.6 7.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SID-1_RNA_chan PF13965.1 ETO18248.1 - 2.3 6.2 5.4 2.9 5.9 3.7 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF3530 PF12048.3 ETO18248.1 - 6.4 5.6 7.7 13 4.5 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Serinc PF03348.10 ETO18249.1 - 2.2e-28 99.1 2.9 2.9e-28 98.7 2.0 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF1510 PF07423.6 ETO18249.1 - 0.0024 17.2 5.2 0.003 16.9 2.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) O-ag_pol_Wzy PF14296.1 ETO18249.1 - 0.035 12.6 12.5 0.53 8.8 8.7 2.1 1 1 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy Spo7 PF03907.8 ETO18249.1 - 0.036 13.6 0.1 0.056 13.0 0.1 1.3 1 0 0 1 1 1 0 Spo7-like protein Tmemb_14 PF03647.8 ETO18249.1 - 0.071 13.5 4.3 0.28 11.6 0.2 2.9 2 1 1 3 3 3 0 Transmembrane proteins 14C DAD PF02109.11 ETO18249.1 - 0.073 13.1 7.2 1.3 9.0 1.6 2.5 2 0 0 2 2 2 0 DAD family Ninjurin PF04923.7 ETO18249.1 - 0.43 10.3 2.7 17 5.1 1.9 2.7 1 1 0 1 1 1 0 Ninjurin NPR3 PF03666.8 ETO18249.1 - 0.56 8.6 3.5 0.85 8.0 2.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4131 PF13567.1 ETO18249.1 - 2.4 7.5 12.3 8 5.8 1.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Glycolipid_bind PF06475.6 ETO18250.1 - 0.011 14.8 0.3 0.026 13.6 0.2 1.6 1 1 0 1 1 1 0 Putative glycolipid-binding ABA_GPCR PF12430.3 ETO18250.1 - 0.051 12.7 0.6 0.085 11.9 0.4 1.4 1 0 0 1 1 1 0 Abscisic acid G-protein coupled receptor Bac_surface_Ag PF01103.18 ETO18250.1 - 0.44 9.9 4.1 0.65 9.4 2.9 1.2 1 0 0 1 1 1 0 Surface antigen Toxin_55 PF15606.1 ETO18252.1 - 1.3 9.0 4.3 1.3 9.0 1.2 2.4 2 1 0 2 2 2 0 Putative toxin 55 APG17 PF04108.7 ETO18253.1 - 4.5e-11 42.1 0.8 4.5e-11 42.1 0.5 3.1 2 1 0 2 2 2 1 Autophagy protein Apg17 PRT_C PF08372.5 ETO18254.1 - 7.7e-05 22.2 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 Plant phosphoribosyltransferase C-terminal HSDR_N PF04313.9 ETO18254.1 - 0.023 14.4 1.6 0.032 13.9 1.1 1.2 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Pex24p PF06398.6 ETO18254.1 - 0.055 12.2 0.2 0.077 11.7 0.1 1.4 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Rabaptin PF03528.10 ETO18254.1 - 0.065 13.1 2.3 0.13 12.1 1.6 1.5 1 0 0 1 1 1 0 Rabaptin Macoilin PF09726.4 ETO18254.1 - 2.6 6.1 15.6 0.068 11.4 5.0 2.1 1 1 1 2 2 2 0 Transmembrane protein bPH_3 PF14470.1 ETO18256.1 - 0.029 14.6 1.0 6.5 7.0 0.9 2.3 1 1 1 2 2 2 0 Bacterial PH domain Lipoprotein_9 PF03180.9 ETO18256.1 - 0.063 12.1 0.1 0.086 11.7 0.1 1.1 1 0 0 1 1 1 0 NLPA lipoprotein DUF2457 PF10446.4 ETO18258.1 - 0.0048 15.6 11.8 0.007 15.1 8.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Utp14 PF04615.8 ETO18258.1 - 0.0089 14.2 7.9 0.012 13.8 5.5 1.1 1 0 0 1 1 1 1 Utp14 protein Spot_14 PF07084.7 ETO18258.1 - 0.27 11.0 1.8 0.67 9.8 0.6 1.9 2 0 0 2 2 2 0 Thyroid hormone-inducible hepatic protein Spot 14 Ribosomal_60s PF00428.14 ETO18258.1 - 0.81 10.1 9.0 12 6.3 3.2 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Utp14 PF04615.8 ETO18259.1 - 0.12 10.4 11.6 0.15 10.2 8.1 1.1 1 0 0 1 1 1 0 Utp14 protein OPT PF03169.10 ETO18259.1 - 0.38 9.1 2.8 0.53 8.6 2.0 1.2 1 0 0 1 1 1 0 OPT oligopeptide transporter protein DUF966 PF06136.8 ETO18259.1 - 3.3 7.0 12.1 4 6.7 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) FH2 PF02181.18 ETO18261.1 - 6.8e-71 239.0 15.1 6.8e-71 239.0 10.4 3.0 3 0 0 3 3 3 1 Formin Homology 2 Domain OPT PF03169.10 ETO18261.1 - 0.15 10.4 0.0 0.23 9.8 0.0 1.1 1 0 0 1 1 1 0 OPT oligopeptide transporter protein Mpp10 PF04006.7 ETO18262.1 - 2.2e-36 125.4 47.7 2e-29 102.4 13.1 2.4 2 1 0 2 2 2 2 Mpp10 protein NSP2-B_epitope PF14757.1 ETO18262.1 - 0.067 12.6 0.1 0.32 10.4 0.0 1.9 2 0 0 2 2 2 0 Immunogenic region of nsp2 protein of arterivirus polyprotein HATPase_c PF02518.21 ETO18263.1 - 3.7e-21 74.9 0.3 1.8e-20 72.7 0.0 2.1 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 ETO18263.1 - 2e-05 24.2 0.6 6.8e-05 22.5 0.4 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase OspD PF03207.8 ETO18263.1 - 0.014 14.5 1.1 0.02 14.0 0.8 1.2 1 0 0 1 1 1 0 Borrelia outer surface protein D (OspD) DUF3160 PF11369.3 ETO18263.1 - 0.021 13.1 0.3 0.029 12.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3160) HATPase_c_2 PF13581.1 ETO18263.1 - 0.095 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HisKA PF00512.20 ETO18263.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain ParB PF08775.5 ETO18263.1 - 0.16 12.2 1.8 0.21 11.9 0.6 1.7 1 1 0 1 1 1 0 ParB family SSF PF00474.12 ETO18264.1 - 3.8e-18 65.3 31.7 7.1e-18 64.4 21.9 1.5 1 1 0 1 1 1 1 Sodium:solute symporter family DDE_Tnp_IS1595 PF12762.2 ETO18265.1 - 1.5e-38 132.0 0.4 2e-38 131.5 0.3 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain Zn_Tnp_IS1595 PF12760.2 ETO18265.1 - 3e-11 42.9 4.7 5.1e-11 42.2 3.3 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain CpXC PF14353.1 ETO18265.1 - 0.04 13.8 0.3 0.11 12.4 0.2 1.8 1 1 0 1 1 1 0 CpXC protein rve_2 PF13333.1 ETO18265.1 - 0.058 13.4 0.3 0.15 12.1 0.2 1.7 1 0 0 1 1 1 0 Integrase core domain Sigma70_r4_2 PF08281.7 ETO18265.1 - 0.099 12.1 0.0 0.65 9.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 PA28_beta PF02252.13 ETO18266.1 - 3.6e-41 140.1 3.0 3.6e-41 140.1 2.1 1.7 2 0 0 2 2 2 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.13 ETO18266.1 - 0.028 14.5 0.9 0.061 13.5 0.1 2.0 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit DUF3994 PF13159.1 ETO18266.1 - 0.87 9.8 11.5 3.6 7.8 1.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3994) DXP_synthase_N PF13292.1 ETO18266.1 - 1.3 7.9 5.3 1.2 7.9 2.4 1.8 1 1 1 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Tox-SHH PF15652.1 ETO18266.1 - 1.5 9.4 5.7 3.1 8.4 2.9 2.4 2 1 1 3 3 3 0 HNH/Endo VII superfamily toxin with a SHH signature Aldo_ket_red PF00248.16 ETO18267.1 - 9e-10 37.8 0.1 1.1e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 ETO18268.1 - 5.7e-19 68.0 0.0 7e-19 67.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PBP1_TM PF14812.1 ETO18269.1 - 0.095 13.0 4.2 0.2 11.9 2.9 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sulfotransfer_2 PF03567.9 ETO18270.1 - 9.1e-08 32.0 1.4 3.7e-06 26.8 1.0 2.7 1 1 0 1 1 1 1 Sulfotransferase family EcsB PF05975.7 ETO18270.1 - 0.25 9.7 4.6 0.042 12.3 0.4 1.6 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB Herpes_LMP1 PF05297.6 ETO18271.1 - 0.073 11.9 5.6 0.23 10.3 3.3 1.9 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) WD40 PF00400.27 ETO18272.1 - 2.4e-56 185.6 19.7 4.3e-12 45.4 0.1 7.2 6 1 1 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO18272.1 - 3.7e-10 38.5 1.2 0.032 12.3 0.0 4.9 1 1 4 5 5 5 5 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO18272.1 - 0.0022 17.7 3.0 0.96 9.1 0.1 3.7 1 1 3 5 5 5 2 Eukaryotic translation initiation factor eIF2A rRNA_methylase PF06962.7 ETO18272.1 - 0.073 12.7 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 Putative rRNA methylase PEP_mutase PF13714.1 ETO18273.1 - 9.1e-43 146.1 0.1 1.1e-42 145.9 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 ETO18273.1 - 8.9e-17 60.4 0.1 1e-16 60.2 0.1 1.3 1 0 0 1 1 1 1 Isocitrate lyase family WD40 PF00400.27 ETO18275.1 - 8.6e-42 139.5 11.1 3.6e-11 42.5 0.0 5.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO18275.1 - 0.00037 19.3 1.5 0.58 8.8 0.1 2.8 1 1 1 2 2 2 2 Nup133 N terminal like BBS2_Mid PF14783.1 ETO18275.1 - 0.0069 16.1 0.1 5 6.9 0.0 3.5 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.1 ETO18275.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.3 1 1 0 1 1 1 0 PQQ-like domain Nbas_N PF15492.1 ETO18275.1 - 0.023 13.8 0.6 0.42 9.6 0.1 2.7 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 ETO18275.1 - 0.089 10.9 4.1 2.8 5.9 0.4 3.5 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO18275.1 - 0.11 10.7 0.0 0.38 8.9 0.0 1.7 1 1 1 2 2 2 0 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 ETO18275.1 - 0.15 10.8 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region HEAT_2 PF13646.1 ETO18277.1 - 9.4e-15 54.6 0.0 0.00098 19.3 0.0 4.8 3 2 1 4 4 4 3 HEAT repeats HEAT PF02985.17 ETO18277.1 - 3e-07 29.9 0.5 0.17 12.0 0.0 7.4 10 0 0 10 10 10 1 HEAT repeat HEAT_EZ PF13513.1 ETO18277.1 - 2.4e-06 27.8 0.0 0.032 14.7 0.0 5.6 5 1 1 6 6 6 1 HEAT-like repeat Cnd1 PF12717.2 ETO18277.1 - 3.3e-06 27.0 27.6 4.6e-05 23.3 0.1 5.3 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 DUF3907 PF13047.1 ETO18277.1 - 0.0071 15.9 1.2 0.55 9.8 0.0 3.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3907) DUF3535 PF12054.3 ETO18277.1 - 0.016 13.8 0.0 2.2 6.7 0.0 3.6 1 1 2 4 4 4 0 Domain of unknown function (DUF3535) DNA_pol_B_palm PF14792.1 ETO18278.1 - 7.3e-30 103.3 0.0 8.3e-29 99.9 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 ETO18278.1 - 2.7e-22 78.2 0.0 1.1e-21 76.3 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 ETO18278.1 - 1.8e-15 56.1 0.1 4.4e-15 54.9 0.1 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 ETO18278.1 - 1.3e-12 47.6 0.3 1.3e-11 44.4 0.0 2.7 3 0 0 3 3 3 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 ETO18278.1 - 7.3e-05 23.0 0.0 0.00018 21.7 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain HHH_3 PF12836.2 ETO18278.1 - 0.074 12.9 1.2 0.21 11.5 0.2 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif Sigma_reg_C PF13791.1 ETO18278.1 - 0.098 12.6 0.8 0.88 9.5 0.2 2.4 2 0 0 2 2 2 0 Sigma factor regulator C-terminal Cpn60_TCP1 PF00118.19 ETO18279.1 - 1.3e-65 221.9 1.5 7.1e-35 120.5 0.2 2.0 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.19 ETO18280.1 - 5e-13 48.4 0.0 5.6e-13 48.3 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ADIP PF11559.3 ETO18281.1 - 0.0062 16.4 10.9 0.0062 16.4 7.6 3.8 2 1 2 4 4 4 1 Afadin- and alpha -actinin-Binding Tissue_fac PF01108.12 ETO18281.1 - 0.013 15.1 1.6 0.045 13.5 1.1 1.9 1 1 0 1 1 1 0 Tissue factor Tropomyosin_1 PF12718.2 ETO18281.1 - 0.016 15.0 11.2 0.016 15.0 7.8 4.1 2 2 1 3 3 3 0 Tropomyosin like HGTP_anticodon PF03129.15 ETO18281.1 - 0.64 10.0 5.6 0.64 9.9 0.6 2.7 2 1 0 3 3 3 0 Anticodon binding domain ArgK PF03308.11 ETO18281.1 - 0.68 8.6 3.9 0.27 9.9 0.8 1.7 1 1 0 1 1 1 0 ArgK protein bZIP_1 PF00170.16 ETO18281.1 - 0.96 9.4 32.8 0.14 12.1 1.2 5.4 4 2 1 5 5 5 0 bZIP transcription factor PP2 PF14299.1 ETO18281.1 - 3.1 7.1 8.4 2.1 7.7 4.2 2.1 1 1 0 1 1 1 0 Phloem protein 2 RCC1 PF00415.13 ETO18282.1 - 6.6e-25 87.0 9.3 8.5e-08 32.2 0.5 5.3 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO18282.1 - 2.4e-20 71.5 15.2 1.6e-09 37.0 0.4 3.4 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat WD40 PF00400.27 ETO18284.1 - 8e-32 107.9 12.0 2.9e-11 42.8 0.2 4.5 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO18284.1 - 6.5e-07 27.8 1.0 0.013 13.7 0.1 2.8 1 1 2 3 3 3 3 Nucleoporin Nup120/160 MFS_1 PF07690.11 ETO18285.1 - 0.00012 20.9 0.0 0.00015 20.6 0.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sigma70_ner PF04546.8 ETO18285.1 - 0.0021 17.7 3.3 0.0028 17.3 2.3 1.1 1 0 0 1 1 1 1 Sigma-70, non-essential region Ebola_NP PF05505.7 ETO18285.1 - 0.67 7.9 5.3 0.82 7.6 3.6 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein PGK PF00162.14 ETO18286.1 - 4.7e-108 361.1 0.2 8.1e-108 360.3 0.1 1.4 1 0 0 1 1 1 1 Phosphoglycerate kinase Gp_dh_C PF02800.15 ETO18286.1 - 4.3e-58 195.2 0.3 9.4e-58 194.1 0.2 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 ETO18286.1 - 5.6e-47 159.4 2.5 1e-46 158.6 1.0 2.1 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain HTH_25 PF13413.1 ETO18286.1 - 5.6e-17 61.1 0.0 1.5e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain Polyketide_cyc PF03364.15 ETO18286.1 - 1.6e-06 28.1 0.0 3.4e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport HTH_19 PF12844.2 ETO18286.1 - 5.7e-06 26.2 0.0 2.1e-05 24.4 0.0 2.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.17 ETO18286.1 - 3.3e-05 23.6 0.2 0.00011 22.0 0.1 2.0 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 ETO18286.1 - 0.0031 17.6 0.0 0.0072 16.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Yqai PF09466.5 ETO18286.1 - 0.0055 16.6 0.2 2 8.4 0.0 3.4 3 0 0 3 3 3 1 Hypothetical protein Yqai F420_oxidored PF03807.12 ETO18286.1 - 0.096 13.1 2.9 0.23 11.9 0.2 2.8 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Rxt3 PF08642.5 ETO18288.1 - 0.098 12.8 7.7 0.03 14.5 2.2 2.2 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Sigma70_ner PF04546.8 ETO18289.1 - 0.15 11.6 0.9 2 7.9 0.1 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region WD40 PF00400.27 ETO18290.1 - 3.2e-15 55.3 9.2 1.4e-05 24.7 0.2 4.9 4 1 0 4 4 4 3 WD domain, G-beta repeat PQQ_2 PF13360.1 ETO18290.1 - 0.01 15.3 0.0 0.25 10.7 0.1 2.5 1 1 0 2 2 2 0 PQQ-like domain Kelch_6 PF13964.1 ETO18291.1 - 1.3e-08 34.6 2.6 0.052 13.7 0.3 4.5 4 1 1 5 5 5 3 Kelch motif Kelch_1 PF01344.20 ETO18291.1 - 7.4e-08 31.8 1.2 0.0078 15.7 0.2 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETO18291.1 - 3.3e-07 29.9 0.1 0.0025 17.5 0.0 3.3 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO18291.1 - 6.6e-07 28.8 0.7 0.016 14.9 0.1 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO18291.1 - 0.00018 21.4 1.1 2.8 8.0 0.0 4.3 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 ETO18291.1 - 0.0003 20.8 0.0 0.094 12.9 0.0 3.5 4 0 0 4 4 4 1 Galactose oxidase, central domain Zip PF02535.17 ETO18292.1 - 0.054 12.4 0.3 0.098 11.6 0.2 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Menin PF05053.8 ETO18292.1 - 1.3 7.0 11.9 1.8 6.6 8.2 1.1 1 0 0 1 1 1 0 Menin Tetraspannin PF00335.15 ETO18292.1 - 1.4 8.1 10.1 0.4 9.9 3.7 2.1 2 0 0 2 2 2 0 Tetraspanin family GET2 PF08690.5 ETO18292.1 - 3.8 6.6 12.9 6.7 5.8 8.9 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 DUF4551 PF15087.1 ETO18292.1 - 6.1 5.0 8.2 8.3 4.6 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) RabGAP-TBC PF00566.13 ETO18292.1 - 7.3 5.9 13.2 1.5 8.2 6.0 2.2 2 1 0 2 2 2 0 Rab-GTPase-TBC domain Med18 PF09637.5 ETO18294.1 - 1.3e-06 28.1 2.3 0.00025 20.6 0.5 2.2 1 1 1 2 2 2 2 Med18 protein Vps51 PF08700.6 ETO18294.1 - 0.022 14.5 0.1 0.23 11.3 0.0 2.3 2 0 0 2 2 2 0 Vps51/Vps67 SapB_1 PF05184.10 ETO18294.1 - 0.039 13.7 0.8 0.11 12.3 0.1 2.1 2 0 0 2 2 2 0 Saposin-like type B, region 1 Borrelia_orfX PF04160.7 ETO18294.1 - 0.32 10.8 5.4 3.8 7.3 1.8 2.2 1 1 1 2 2 2 0 Orf-X protein NDUFA12 PF05071.11 ETO18295.1 - 7.8e-18 64.8 6.6 2.8e-16 59.8 4.6 2.2 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 SusD-like_3 PF14322.1 ETO18297.1 - 0.04 13.9 1.9 0.091 12.8 0.1 2.0 1 1 1 2 2 2 0 Starch-binding associating with outer membrane PRP1_N PF06424.7 ETO18297.1 - 0.083 13.2 5.9 1.7 8.9 0.3 2.5 3 0 0 3 3 3 0 PRP1 splicing factor, N-terminal DUF2746 PF10874.3 ETO18297.1 - 0.17 12.0 0.4 0.17 12.0 0.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2746) DUF1296 PF06972.6 ETO18298.1 - 0.77 9.7 3.9 10 6.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) RSN1_TM PF13967.1 ETO18299.1 - 0.0041 16.6 0.0 0.0041 16.6 0.0 2.1 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PH_4 PF15404.1 ETO18299.1 - 0.071 12.6 1.2 0.1 12.1 0.8 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain Secretin_N_2 PF07655.8 ETO18299.1 - 2.7 8.4 16.8 4.3 7.8 11.7 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain Sulfate_transp PF00916.15 ETO18300.1 - 2.2e-29 102.3 0.7 2.8e-29 102.0 0.5 1.1 1 0 0 1 1 1 1 Sulfate transporter family DUF4181 PF13789.1 ETO18300.1 - 3.6 7.5 6.6 0.24 11.3 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) DPM3 PF08285.6 ETO18300.1 - 6 6.7 6.2 0.43 10.4 0.1 2.2 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) STAS PF01740.16 ETO18301.1 - 3.1e-18 65.2 0.0 5e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 STAS domain Sulfate_transp PF00916.15 ETO18301.1 - 1.1e-05 24.5 0.2 2.2e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Sulfate transporter family Pkinase_Tyr PF07714.12 ETO18303.1 - 2.1e-43 148.2 0.9 3.3e-29 101.7 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 ETO18303.1 - 2.2e-42 145.0 0.4 1.9e-29 102.5 0.2 2.3 2 0 0 2 2 2 2 Protein kinase domain AroM PF07302.6 ETO18303.1 - 0.021 14.1 0.1 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 AroM protein V_ATPase_I PF01496.14 ETO18305.1 - 0.0021 16.0 15.3 0.0021 16.0 10.6 5.0 2 2 2 4 4 4 1 V-type ATPase 116kDa subunit family DUF972 PF06156.8 ETO18305.1 - 0.012 15.9 7.2 0.012 15.9 5.0 7.4 3 1 2 6 6 6 0 Protein of unknown function (DUF972) DUF4094 PF13334.1 ETO18305.1 - 0.019 15.3 6.0 0.019 15.3 4.2 6.2 3 2 3 6 6 6 0 Domain of unknown function (DUF4094) EF-hand_7 PF13499.1 ETO18306.1 - 4.4e-09 36.3 13.7 1.2e-06 28.5 0.1 4.3 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_8 PF13833.1 ETO18306.1 - 8e-06 25.3 0.8 0.077 12.6 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 ETO18306.1 - 0.0032 16.6 17.1 0.02 14.1 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 ETO18306.1 - 0.0034 17.1 11.9 0.2 11.6 0.0 4.7 5 0 0 5 5 5 3 EF-hand domain Toprim_2 PF13155.1 ETO18306.1 - 0.012 15.9 0.9 0.073 13.4 0.1 2.8 2 0 0 2 2 2 0 Toprim-like Mucin PF01456.12 ETO18308.1 - 0.049 13.3 15.1 0.09 12.5 10.5 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein ABC_tran PF00005.22 ETO18309.1 - 6.5e-28 97.7 0.0 4.1e-27 95.1 0.0 2.4 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.14 ETO18309.1 - 2.6e-07 30.0 0.9 7.7e-06 25.2 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETO18309.1 - 0.0027 17.7 0.3 2 8.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 ETO18309.1 - 0.006 16.5 0.2 0.055 13.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 ETO18309.1 - 0.0094 15.4 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 ETO18309.1 - 0.028 13.8 0.1 1.1 8.5 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain AAA_5 PF07728.9 ETO18309.1 - 0.053 13.2 0.1 1.1 8.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 ETO18309.1 - 0.14 11.9 0.2 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 ETO18309.1 - 0.21 11.7 1.7 1.5 8.9 0.0 2.8 2 2 1 3 3 3 0 AAA domain ETRAMP PF09716.5 ETO18309.1 - 0.4 10.6 3.7 1.5 8.8 0.3 2.7 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) SbcCD_C PF13558.1 ETO18309.1 - 0.47 10.4 3.3 0.66 9.9 0.2 2.8 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit ABC_membrane PF00664.18 ETO18310.1 - 7.9e-12 45.1 0.1 9.2e-12 44.9 0.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region Pkinase PF00069.20 ETO18311.1 - 3.6e-31 108.2 0.0 5.3e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO18311.1 - 3.3e-09 36.2 0.0 4.5e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ubiq_cyt_C_chap PF03981.7 ETO18311.1 - 0.1 12.4 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone Serglycin PF04360.7 ETO18312.1 - 0.0017 18.0 0.4 0.005 16.5 0.3 1.8 1 0 0 1 1 1 1 Serglycin Fibrinogen_aC PF12160.3 ETO18313.1 - 0.091 12.2 0.4 0.18 11.3 0.3 1.4 1 0 0 1 1 1 0 Fibrinogen alpha C domain Ank_4 PF13637.1 ETO18315.1 - 0.044 14.2 0.0 2.5 8.7 0.0 2.7 1 1 1 2 2 2 0 Ankyrin repeats (many copies) GATase_7 PF13537.1 ETO18315.1 - 0.08 12.6 0.1 0.17 11.5 0.0 1.6 2 0 0 2 2 2 0 Glutamine amidotransferase domain ATP-synt_E PF05680.7 ETO18317.1 - 0.11 12.4 0.2 0.26 11.2 0.1 1.9 1 1 1 2 2 2 0 ATP synthase E chain Spore_III_AB PF09548.5 ETO18317.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Clathrin PF00637.15 ETO18318.1 - 0.031 13.8 1.0 0.049 13.2 0.7 1.4 1 0 0 1 1 1 0 Region in Clathrin and VPS UvrD-helicase PF00580.16 ETO18318.1 - 0.069 12.4 5.7 0.082 12.1 4.0 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF3439 PF11921.3 ETO18319.1 - 0.12 12.1 17.8 0.37 10.5 12.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) GIDA PF01134.17 ETO18319.1 - 0.31 9.8 10.2 0.0098 14.7 2.4 2.0 1 1 0 1 1 1 0 Glucose inhibited division protein A RasGEF PF00617.14 ETO18320.1 - 4.1e-26 91.8 1.1 1.1e-25 90.4 0.8 1.8 1 0 0 1 1 1 1 RasGEF domain PUB PF09409.5 ETO18320.1 - 2.7e-11 43.0 0.6 7.9e-11 41.5 0.0 2.1 2 0 0 2 2 2 1 PUB domain RasGEF_N PF00618.15 ETO18320.1 - 7.2e-05 22.8 7.5 0.0014 18.6 5.2 2.8 1 1 0 1 1 1 1 RasGEF N-terminal motif 7TM_GPCR_Srsx PF10320.4 ETO18320.1 - 0.0055 15.8 0.3 0.01 15.0 0.2 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF302 PF03625.9 ETO18320.1 - 0.11 12.0 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF302 SDA1 PF05285.7 ETO18321.1 - 0.086 12.1 6.8 0.11 11.7 4.7 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 ETO18321.1 - 0.32 8.9 5.2 0.37 8.7 3.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Di19_C PF14571.1 ETO18321.1 - 0.99 9.7 4.4 2.4 8.5 1.8 2.2 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal DUF3439 PF11921.3 ETO18322.1 - 2.6 7.8 9.5 0.97 9.1 3.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Menin PF05053.8 ETO18323.1 - 0.033 12.3 10.4 0.044 11.9 7.2 1.2 1 0 0 1 1 1 0 Menin Striatin PF08232.7 ETO18323.1 - 0.64 10.3 35.9 0.57 10.5 15.1 2.3 1 1 1 2 2 2 0 Striatin family RRN3 PF05327.6 ETO18325.1 - 0.026 12.6 3.8 0.039 12.0 2.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Trypan_glycop_C PF10659.4 ETO18325.1 - 0.028 14.7 0.4 0.028 14.7 0.3 1.8 2 0 0 2 2 2 0 Trypanosome variant surface glycoprotein C-terminal domain DUF3393 PF11873.3 ETO18325.1 - 0.057 12.9 0.6 0.077 12.4 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3393) Med3 PF11593.3 ETO18326.1 - 2.2 7.4 20.1 2.8 7.1 14.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DDE_Tnp_1 PF01609.16 ETO18327.1 - 1.3e-14 54.2 0.3 3.2e-14 53.0 0.1 1.7 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_2 PF04693.7 ETO18327.1 - 0.00073 18.6 0.2 0.0014 17.7 0.1 1.4 1 0 0 1 1 1 1 Archaeal putative transposase ISC1217 DUF4372 PF14294.1 ETO18327.1 - 0.0071 16.1 0.1 0.021 14.6 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4372) Aldo_ket_red PF00248.16 ETO18328.1 - 7.2e-42 143.1 0.0 1.1e-41 142.5 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.27 ETO18329.1 - 1.7e-46 154.4 19.7 5.9e-12 44.9 0.0 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO18329.1 - 2.3e-06 26.0 0.9 0.063 11.4 0.0 4.0 1 1 3 4 4 4 3 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO18329.1 - 0.037 13.9 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3601) DAO PF01266.19 ETO18330.1 - 0.0028 16.6 0.0 0.0059 15.5 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.14 ETO18330.1 - 0.052 12.6 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 GMC oxidoreductase MyTH4 PF00784.12 ETO18331.1 - 0.023 14.6 0.1 0.12 12.2 0.0 2.3 2 0 0 2 2 2 0 MyTH4 domain Tautomerase_2 PF14552.1 ETO18331.1 - 0.061 13.3 0.0 0.43 10.6 0.0 2.3 2 0 0 2 2 2 0 Tautomerase enzyme MutS_III PF05192.13 ETO18331.1 - 0.54 10.0 3.1 0.72 9.6 0.7 2.3 2 2 0 2 2 2 0 MutS domain III Scaffolding_pro PF11418.3 ETO18332.1 - 0.29 11.4 2.4 0.33 11.2 0.0 2.2 2 1 1 3 3 3 0 Phi29 scaffolding protein Syntaxin_2 PF14523.1 ETO18333.1 - 0.015 15.3 2.8 0.015 15.3 1.9 1.8 1 1 0 1 1 1 0 Syntaxin-like protein NLBH PF05211.7 ETO18333.1 - 0.015 14.5 0.2 0.02 14.1 0.2 1.2 1 0 0 1 1 1 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) DUF4250 PF14056.1 ETO18333.1 - 0.056 13.1 0.9 0.32 10.7 0.0 2.6 2 1 2 4 4 4 0 Domain of unknown function (DUF4250) Vwaint PF14624.1 ETO18333.1 - 0.15 12.1 1.4 0.44 10.6 0.9 1.9 1 1 0 1 1 1 0 VWA / Hh protein intein-like DUF342 PF03961.8 ETO18333.1 - 0.21 9.9 4.6 0.23 9.8 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4144 PF13642.1 ETO18333.1 - 0.21 11.9 2.9 0.27 11.5 1.6 1.5 1 1 0 1 1 1 0 protein structure with unknown function DASH_Dad2 PF08654.5 ETO18333.1 - 0.45 10.5 4.7 7 6.7 3.2 2.5 1 1 0 1 1 1 0 DASH complex subunit Dad2 DUF2968 PF11180.3 ETO18333.1 - 1 8.7 9.0 0.26 10.6 2.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DUF536 PF04394.9 ETO18333.1 - 1.7 8.4 9.6 0.095 12.4 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF536 LptE PF04390.7 ETO18334.1 - 1.1 8.9 7.0 1.5 8.5 4.9 1.2 1 0 0 1 1 1 0 Lipopolysaccharide-assembly TIP41 PF04176.8 ETO18334.1 - 3.1 6.9 10.3 3.6 6.7 7.1 1.3 1 0 0 1 1 1 0 TIP41-like family Apc15p PF05841.6 ETO18334.1 - 5.9 7.6 19.9 7 7.3 13.2 1.5 1 1 0 1 1 1 0 Apc15p protein TT_ORF1 PF02956.9 ETO18334.1 - 8.1 4.7 23.0 9.5 4.5 15.9 1.1 1 0 0 1 1 1 0 TT viral orf 1 MoCF_biosynth PF00994.19 ETO18335.1 - 2.5e-20 72.3 0.0 2.7e-20 72.2 0.0 1.0 1 0 0 1 1 1 1 Probable molybdopterin binding domain Abhydrolase_5 PF12695.2 ETO18336.1 - 6.5e-05 22.7 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family tRNA-synt_2b PF00587.20 ETO18337.1 - 0.0014 18.2 0.0 0.0029 17.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) BUD22 PF09073.5 ETO18339.1 - 0.02 14.0 9.2 0.023 13.7 6.4 1.1 1 0 0 1 1 1 0 BUD22 Ycf1 PF05758.7 ETO18339.1 - 0.08 10.6 0.6 0.07 10.8 0.4 1.1 1 0 0 1 1 1 0 Ycf1 HSP90 PF00183.13 ETO18339.1 - 0.098 11.0 5.8 0.13 10.6 4.0 1.1 1 0 0 1 1 1 0 Hsp90 protein CobT PF06213.7 ETO18339.1 - 0.11 11.6 8.7 0.17 11.0 6.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT ATP-synt_E PF05680.7 ETO18339.1 - 0.35 10.8 2.0 0.6 10.0 1.4 1.4 1 0 0 1 1 1 0 ATP synthase E chain VID27 PF08553.5 ETO18339.1 - 2.5 6.2 7.3 3.1 5.8 5.1 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein NOA36 PF06524.7 ETO18339.1 - 3.2 6.9 7.2 4.6 6.4 5.0 1.2 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 ETO18339.1 - 3.3 7.2 10.1 5.2 6.5 7.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin TPR_12 PF13424.1 ETO18340.1 - 1.4e-15 56.9 5.5 2.8e-12 46.3 1.5 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO18340.1 - 7.8e-10 37.8 2.6 0.062 13.1 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO18340.1 - 1.4e-09 37.0 3.4 0.0081 16.0 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO18340.1 - 2.2e-08 33.3 1.5 0.29 10.7 0.0 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO18340.1 - 4e-08 32.7 3.9 1e-05 25.0 1.1 2.6 1 1 2 3 3 3 3 TPR repeat TPR_7 PF13176.1 ETO18340.1 - 3.7e-05 23.1 1.9 0.47 10.3 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO18340.1 - 4.1e-05 23.8 3.3 0.38 11.5 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO18340.1 - 8.9e-05 22.5 1.3 0.091 12.9 0.2 2.4 1 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 ETO18340.1 - 0.00051 20.6 2.6 0.03 14.9 0.3 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETO18340.1 - 0.0065 16.3 2.1 0.23 11.4 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO18340.1 - 0.013 15.9 2.4 11 6.7 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETO18340.1 - 0.045 14.0 4.7 2.3 8.6 0.2 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF1837 PF08878.6 ETO18341.1 - 0.037 13.6 1.2 0.056 13.0 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1837) RhoGEF PF00621.15 ETO18342.1 - 7.6e-22 78.0 0.5 7.6e-22 78.0 0.3 1.6 2 0 0 2 2 2 1 RhoGEF domain DDRGK PF09756.4 ETO18342.1 - 0.068 12.5 21.6 0.092 12.1 15.0 1.1 1 0 0 1 1 1 0 DDRGK domain CDC45 PF02724.9 ETO18342.1 - 0.26 9.2 11.0 0.35 8.8 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Spore_coat_CotO PF14153.1 ETO18342.1 - 0.3 10.4 11.9 0.39 10.1 8.2 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF3513 PF12026.3 ETO18342.1 - 0.48 9.9 6.0 0.29 10.6 3.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3513) DUF2058 PF09831.4 ETO18342.1 - 1.2 8.9 14.6 1.8 8.3 10.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) HSP70 PF00012.15 ETO18342.1 - 1.9 6.3 6.7 2.1 6.1 4.7 1.1 1 0 0 1 1 1 0 Hsp70 protein DDHD PF02862.12 ETO18342.1 - 2.7 7.7 10.9 3.9 7.2 7.6 1.2 1 0 0 1 1 1 0 DDHD domain Sec62 PF03839.11 ETO18342.1 - 2.8 7.2 9.2 3.7 6.8 6.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 RR_TM4-6 PF06459.7 ETO18342.1 - 6 6.6 13.4 8.1 6.2 9.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GBP_C PF02841.9 ETO18342.1 - 9.7 5.2 22.7 14 4.7 15.7 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain ADP_ribosyl_GH PF03747.9 ETO18343.1 - 4.5e-16 59.4 0.0 4.6e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase HR1 PF02185.11 ETO18343.1 - 0.19 11.4 0.3 0.19 11.4 0.2 1.7 2 0 0 2 2 2 0 Hr1 repeat WD40 PF00400.27 ETO18344.1 - 6.5e-17 60.7 10.5 6.2e-07 29.0 0.2 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO18344.1 - 0.00076 17.7 0.3 0.3 9.1 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO18344.1 - 0.04 14.1 4.7 1.2 9.4 0.1 3.1 3 1 1 4 4 4 0 Kelch motif CobT PF06213.7 ETO18345.1 - 0.14 11.2 18.4 0.16 11.1 12.7 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.7 ETO18345.1 - 0.27 10.4 16.5 0.27 10.4 11.4 1.1 1 0 0 1 1 1 0 NOA36 protein DUF4101 PF13355.1 ETO18345.1 - 0.3 11.5 5.0 0.27 11.6 2.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4101) Spore_III_AF PF09581.5 ETO18345.1 - 0.36 10.6 9.9 0.41 10.4 6.9 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) DUF2457 PF10446.4 ETO18345.1 - 0.56 8.8 20.4 0.55 8.9 14.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) UNC-79 PF14776.1 ETO18345.1 - 2 6.6 6.6 2.1 6.6 4.6 1.0 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 Pox_Ag35 PF03286.9 ETO18345.1 - 2.5 7.6 15.9 3.1 7.2 11.0 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF1510 PF07423.6 ETO18345.1 - 2.5 7.4 20.3 2.7 7.3 14.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nop14 PF04147.7 ETO18345.1 - 3.3 5.5 23.4 3.4 5.4 16.2 1.0 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 ETO18345.1 - 3.5 5.9 19.5 3.9 5.8 13.5 1.0 1 0 0 1 1 1 0 Daxx Family Vfa1 PF08432.5 ETO18345.1 - 4.4 7.2 17.1 5.4 6.9 11.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Band_3_cyto PF07565.8 ETO18345.1 - 5.9 6.3 6.8 6.7 6.1 4.7 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Packaging_FI PF14000.1 ETO18345.1 - 9.5 6.4 10.9 13 5.9 7.6 1.3 1 0 0 1 1 1 0 DNA packaging protein FI SMAP PF15477.1 ETO18347.1 - 0.59 10.4 3.8 2.9 8.2 0.3 2.4 2 0 0 2 2 2 0 Small acidic protein family Multi-haem_cyto PF13447.1 ETO18348.1 - 0.049 12.6 0.4 0.088 11.8 0.3 1.4 1 0 0 1 1 1 0 Seven times multi-haem cytochrome CxxCH HTH_Tnp_IS630 PF01710.11 ETO18348.1 - 9.3 5.9 13.9 1.4 8.5 1.5 3.1 2 1 1 3 3 3 0 Transposase Peptidase_C54 PF03416.14 ETO18349.1 - 5.7e-38 130.6 0.1 6.6e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 2HCT PF03390.10 ETO18350.1 - 0.044 12.1 0.2 0.048 12.0 0.1 1.1 1 0 0 1 1 1 0 2-hydroxycarboxylate transporter family Ras PF00071.17 ETO18351.1 - 2.9e-07 30.0 0.0 3.8e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO18351.1 - 0.0035 17.8 0.0 0.0053 17.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 ETO18351.1 - 0.037 12.7 4.2 0.058 12.0 2.7 1.5 1 1 0 1 1 1 0 G-protein alpha subunit DUF4414 PF14377.1 ETO18352.1 - 0.001 18.9 3.7 0.001 18.9 2.5 3.4 1 1 1 3 3 3 2 Domain of unknown function (DUF4414) HECT PF00632.20 ETO18353.1 - 4.9e-88 295.3 0.6 4.9e-88 295.3 0.4 2.2 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) TPR_2 PF07719.12 ETO18354.1 - 0.0034 17.1 3.3 0.046 13.6 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO18354.1 - 0.093 12.6 1.1 6.5 6.7 0.2 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO18354.1 - 0.1 13.1 0.0 2.8 8.5 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF848 PF05852.6 ETO18354.1 - 2.4 8.0 7.0 0.39 10.5 0.9 2.5 3 0 0 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) TPR_2 PF07719.12 ETO18355.1 - 2e-09 36.6 4.4 1.3 9.1 0.3 6.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 ETO18355.1 - 0.00015 21.5 9.2 5.5 7.0 0.5 6.2 4 2 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO18355.1 - 0.00043 19.7 11.5 4.6 7.0 0.1 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO18355.1 - 0.0006 19.4 4.3 2.5 8.0 0.0 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO18355.1 - 0.003 17.2 13.3 3 7.8 0.4 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO18355.1 - 0.0097 15.5 7.6 0.48 10.1 0.2 4.7 3 1 1 4 4 4 1 TPR repeat TPR_9 PF13371.1 ETO18355.1 - 0.024 14.4 1.8 11 5.9 0.1 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETO18355.1 - 0.027 15.0 1.7 18 6.3 0.1 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO18355.1 - 0.044 14.2 4.1 1.1e+02 3.5 0.3 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETO18355.1 - 0.078 13.6 1.7 6.4 7.5 0.1 3.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 ETO18355.1 - 0.087 12.7 1.9 13 5.8 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Myc_N PF01056.13 ETO18355.1 - 7.4 5.6 19.5 0.3 10.2 6.9 2.4 2 0 0 2 2 2 0 Myc amino-terminal region zf-UBR PF02207.15 ETO18356.1 - 3.6e-11 42.6 11.2 3.6e-11 42.6 7.8 4.3 4 1 1 5 5 5 1 Putative zinc finger in N-recognin (UBR box) GlcNAc PF11397.3 ETO18357.1 - 7.7e-51 173.2 1.1 1.2e-49 169.3 0.8 2.1 1 1 0 1 1 1 1 Glycosyltransferase (GlcNAc) Glyco_trans_2_3 PF13632.1 ETO18357.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Stk19 PF10494.4 ETO18358.1 - 3e-22 79.2 3.5 7.7e-18 64.7 0.1 2.7 2 1 1 3 3 3 2 Serine-threonine protein kinase 19 DUF4304 PF14137.1 ETO18358.1 - 0.062 13.4 0.7 1.2 9.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4304) PWWP PF00855.12 ETO18359.1 - 5.8e-06 26.4 0.0 1.2e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 PWWP domain CDC45 PF02724.9 ETO18359.1 - 0.67 7.9 2.4 0.84 7.5 1.7 1.1 1 0 0 1 1 1 0 CDC45-like protein TTL PF03133.10 ETO18361.1 - 2.6e-62 210.4 7.8 6e-44 150.1 2.6 2.4 2 1 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 ETO18361.1 - 2.4e-05 23.2 0.4 0.0098 14.7 0.0 2.8 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 ETO18361.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain S1FA PF04689.8 ETO18361.1 - 0.11 12.4 0.5 0.24 11.2 0.4 1.5 1 0 0 1 1 1 0 DNA binding protein S1FA CSD PF00313.17 ETO18362.1 - 8.3e-09 35.1 0.4 6e-06 25.9 0.0 4.0 4 0 0 4 4 4 2 'Cold-shock' DNA-binding domain tRNA-synt_1g PF09334.6 ETO18364.1 - 1.4e-44 152.3 0.6 7.7e-43 146.6 0.4 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 ETO18364.1 - 0.014 13.4 0.1 0.73 7.7 0.0 2.3 1 1 1 2 2 2 0 tRNA synthetases class I (I, L, M and V) YL1_C PF08265.6 ETO18364.1 - 0.037 13.5 0.1 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain Arm PF00514.18 ETO18365.1 - 3e-09 36.3 0.3 0.024 14.4 0.0 3.3 3 0 0 3 3 3 3 Armadillo/beta-catenin-like repeat PI3_PI4_kinase PF00454.22 ETO18366.1 - 5.5e-05 22.7 1.5 0.00012 21.6 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase Rabaptin PF03528.10 ETO18366.1 - 0.015 15.2 0.2 0.2 11.5 0.3 2.0 1 1 1 2 2 2 0 Rabaptin Gb3_synth PF04572.7 ETO18366.1 - 0.065 12.9 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Alpha 1,4-glycosyltransferase conserved region HMG_box_5 PF14887.1 ETO18366.1 - 0.12 12.1 2.7 0.62 9.8 1.8 2.3 1 1 0 1 1 1 0 HMG (high mobility group) box 5 Osteoregulin PF07175.6 ETO18366.1 - 0.17 11.6 2.6 0.29 10.9 1.8 1.4 1 0 0 1 1 1 0 Osteoregulin Atg14 PF10186.4 ETO18366.1 - 0.38 9.6 4.3 0.42 9.5 3.0 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ENT PF03735.9 ETO18366.1 - 0.54 10.0 2.7 0.95 9.2 0.5 2.4 3 0 0 3 3 3 0 ENT domain zf-RING_2 PF13639.1 ETO18368.1 - 0.0044 16.8 20.5 0.0071 16.1 14.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.1 ETO18368.1 - 0.0085 15.8 7.0 0.015 15.0 4.9 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.1 ETO18368.1 - 0.01 15.4 15.2 0.019 14.6 10.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO18368.1 - 0.025 14.5 21.6 0.048 13.6 15.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 ETO18368.1 - 0.48 10.3 14.5 7.6 6.5 10.8 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 ETO18368.1 - 1.3 8.8 15.5 2.7 7.7 10.8 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Vps39_2 PF10367.4 ETO18368.1 - 2 8.6 13.0 4.2 7.5 5.9 2.4 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 DUF4205 PF13898.1 ETO18369.1 - 7.7e-23 80.7 0.2 6e-22 77.8 0.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4205) Peptidase_S64 PF08192.6 ETO18370.1 - 0.022 13.1 1.6 0.026 12.8 1.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF4012 PF13196.1 ETO18370.1 - 0.025 14.7 0.0 0.042 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4012) SID-1_RNA_chan PF13965.1 ETO18370.1 - 0.082 11.0 0.2 0.13 10.3 0.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MHCassoc_trimer PF08831.5 ETO18370.1 - 0.37 10.6 2.5 0.57 10.0 0.1 2.2 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain CDC45 PF02724.9 ETO18370.1 - 0.46 8.4 8.1 0.69 7.8 5.6 1.3 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 ETO18370.1 - 0.76 7.3 5.0 0.88 7.1 3.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.11 ETO18370.1 - 6.5 6.5 6.3 9 6.1 4.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Macoilin PF09726.4 ETO18370.1 - 9 4.4 13.3 11 4.1 9.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Lum_binding PF00677.12 ETO18371.1 - 0.024 14.5 1.2 0.18 11.7 0.0 2.4 1 1 1 2 2 2 0 Lumazine binding domain Spc7 PF08317.6 ETO18371.1 - 0.032 12.8 0.1 0.04 12.5 0.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Mitofilin PF09731.4 ETO18371.1 - 0.043 12.4 0.6 0.054 12.1 0.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF342 PF03961.8 ETO18371.1 - 0.058 11.8 0.0 0.07 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1409 PF07197.7 ETO18371.1 - 0.086 12.9 0.2 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) AA_permease PF00324.16 ETO18372.1 - 1.6e-24 86.1 23.3 2e-24 85.8 16.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETO18372.1 - 2.2e-05 23.1 23.1 2.2e-05 23.1 16.0 1.7 1 1 1 2 2 2 1 Amino acid permease DUF2207 PF09972.4 ETO18372.1 - 0.61 8.6 10.5 88 1.4 7.3 2.2 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) WBP-1 PF11669.3 ETO18372.1 - 2.4 8.2 4.1 14 5.8 0.0 2.7 3 0 0 3 3 3 0 WW domain-binding protein 1 MCLC PF05934.6 ETO18372.1 - 8.5 4.5 9.0 15 3.6 6.2 1.3 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) ThylakoidFormat PF11264.3 ETO18373.1 - 0.06 12.9 0.1 0.085 12.4 0.1 1.1 1 0 0 1 1 1 0 Thylakoid formation protein AAA_11 PF13086.1 ETO18375.1 - 0.18 11.3 9.2 0.25 10.9 6.4 1.3 1 1 0 1 1 1 0 AAA domain Daxx PF03344.10 ETO18375.1 - 0.21 10.0 26.7 0.31 9.4 18.5 1.3 1 0 0 1 1 1 0 Daxx Family TRAP_alpha PF03896.11 ETO18375.1 - 1.1 8.2 7.4 2.1 7.2 5.1 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4407 PF14362.1 ETO18375.1 - 2.8 6.8 6.3 3.9 6.3 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Trypan_PARP PF05887.6 ETO18375.1 - 6.1 6.6 27.0 2.8 7.7 2.6 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) NUDIX PF00293.23 ETO18376.1 - 1.1e-17 63.9 0.0 3.9e-17 62.1 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain UCH PF00443.24 ETO18377.1 - 5.4e-41 140.4 0.2 1.6e-25 89.7 0.1 2.8 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO18377.1 - 3.8e-20 72.5 0.0 1.4e-11 44.3 0.0 2.9 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UN_NPL4 PF11543.3 ETO18377.1 - 5.1e-05 23.4 0.3 0.0083 16.3 0.0 3.3 3 0 0 3 3 3 1 Nuclear pore localisation protein NPL4 Ubiquitin_2 PF14560.1 ETO18377.1 - 0.00063 19.9 0.1 0.01 16.0 0.0 2.8 2 0 0 2 2 2 1 Ubiquitin-like domain ubiquitin PF00240.18 ETO18377.1 - 0.0042 16.4 0.0 0.018 14.4 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family MIP-T3 PF10243.4 ETO18378.1 - 0.00054 18.5 20.8 0.00068 18.2 14.4 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CDC45 PF02724.9 ETO18378.1 - 0.021 12.9 15.6 0.03 12.3 10.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Apis_Csd PF11671.3 ETO18378.1 - 6.7 6.4 22.4 4.2 7.1 13.4 2.3 2 0 0 2 2 2 0 Complementary sex determiner protein Archease PF01951.11 ETO18379.1 - 0.018 14.9 0.4 0.047 13.6 0.3 1.8 1 0 0 1 1 1 0 Archease protein family (MTH1598/TM1083) SPC25 PF06703.6 ETO18380.1 - 4 6.9 6.1 5.6 6.5 3.7 1.6 1 1 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Ank_5 PF13857.1 ETO18381.1 - 0.00029 20.9 0.2 0.00085 19.4 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO18381.1 - 0.034 14.4 0.0 0.096 13.0 0.0 1.8 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) BTB_2 PF02214.17 ETO18382.1 - 2.7e-06 27.5 0.3 0.00011 22.3 0.0 3.0 2 0 0 2 2 2 1 BTB/POZ domain FF PF01846.14 ETO18382.1 - 0.017 15.0 0.0 0.074 13.0 0.0 2.1 1 0 0 1 1 1 0 FF domain PBP1_TM PF14812.1 ETO18382.1 - 5.1 7.4 10.6 18 5.7 7.3 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_M10 PF00413.19 ETO18383.1 - 1.8e-19 70.0 0.1 7.1e-19 68.0 0.1 2.0 1 1 0 1 1 1 1 Matrixin PG_binding_1 PF01471.13 ETO18383.1 - 6.2e-18 64.5 0.2 1.2e-17 63.5 0.1 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain PG_binding_2 PF08823.6 ETO18383.1 - 0.0064 16.5 0.1 0.0064 16.5 0.0 1.9 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Reprolysin_3 PF13582.1 ETO18383.1 - 0.017 15.6 0.1 0.046 14.2 0.1 1.8 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 ETO18383.1 - 0.055 13.5 0.1 0.15 12.0 0.1 1.8 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 ETO18383.1 - 0.068 12.6 0.7 0.75 9.2 0.0 2.3 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like DUF3796 PF12676.2 ETO18383.1 - 0.68 10.1 7.4 0.08 13.1 1.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) Tyrosinase PF00264.15 ETO18384.1 - 2.1e-11 44.4 0.1 2.1e-11 44.4 0.1 3.2 2 2 0 2 2 2 1 Common central domain of tyrosinase Mitofilin PF09731.4 ETO18384.1 - 3.1 6.3 26.9 4.8 5.7 18.7 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CAF-1_p150 PF11600.3 ETO18386.1 - 4.5 6.5 32.5 12 5.1 22.5 1.7 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal NicO PF03824.11 ETO18388.1 - 0.00011 21.6 0.0 0.00012 21.5 0.0 1.1 1 0 0 1 1 1 1 High-affinity nickel-transport protein TraQ PF09679.5 ETO18388.1 - 0.014 15.2 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) Helicase_C PF00271.26 ETO18389.1 - 8e-23 80.1 0.1 1.4e-22 79.3 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF830 PF05708.7 ETO18389.1 - 0.027 14.4 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Orthopoxvirus protein of unknown function (DUF830) CAF-1_p150 PF11600.3 ETO18390.1 - 0.025 13.9 30.6 0.04 13.3 21.2 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal IncA PF04156.9 ETO18390.1 - 0.11 12.0 6.3 0.14 11.7 4.3 1.2 1 0 0 1 1 1 0 IncA protein Utp14 PF04615.8 ETO18390.1 - 0.39 8.8 36.7 0.48 8.5 25.4 1.0 1 0 0 1 1 1 0 Utp14 protein PA26 PF04636.8 ETO18390.1 - 0.49 9.0 14.5 0.62 8.6 10.1 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4407 PF14362.1 ETO18390.1 - 5.1 5.9 14.5 6.3 5.6 10.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Macoilin PF09726.4 ETO18390.1 - 8.3 4.5 36.8 10 4.2 25.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Kelch_6 PF13964.1 ETO18391.1 - 1.3e-07 31.4 1.6 0.0019 18.3 0.0 4.5 3 1 1 4 4 4 1 Kelch motif Kelch_3 PF13415.1 ETO18391.1 - 3.3e-06 27.1 0.1 0.0018 18.3 0.0 3.4 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO18391.1 - 1.2e-05 24.7 5.0 0.0013 18.2 0.0 3.8 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO18391.1 - 0.00012 21.7 0.0 0.92 9.3 0.0 3.8 3 0 0 3 3 3 2 Galactose oxidase, central domain DUF3439 PF11921.3 ETO18392.1 - 0.044 13.5 6.4 0.12 12.0 4.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) zf-C2H2_4 PF13894.1 ETO18393.1 - 0.13 12.6 6.8 1.9 8.9 0.5 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 ETO18393.1 - 2.9 8.4 14.8 0.58 10.6 1.8 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF1088 PF06469.6 ETO18395.1 - 0.0025 17.2 0.2 0.0025 17.2 0.1 1.7 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1088) Herpes_BLRF2 PF05812.7 ETO18396.1 - 0.0024 17.6 7.0 0.0024 17.6 4.9 2.2 2 1 0 2 2 2 1 Herpesvirus BLRF2 protein Cauli_AT PF03233.8 ETO18396.1 - 0.006 16.3 7.2 0.009 15.7 5.0 1.4 1 0 0 1 1 1 1 Aphid transmission protein Nup54 PF13874.1 ETO18396.1 - 0.013 15.2 9.3 0.015 14.9 6.3 1.3 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 CENP-R PF06729.7 ETO18396.1 - 0.015 14.9 5.5 0.025 14.2 3.8 1.4 1 0 0 1 1 1 0 Kinetochore component, CENP-R DivIC PF04977.10 ETO18396.1 - 0.022 14.2 10.4 0.022 14.2 7.2 2.6 1 1 2 3 3 3 0 Septum formation initiator DUF1465 PF07323.7 ETO18396.1 - 0.025 14.1 2.8 0.034 13.7 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) LCD1 PF09798.4 ETO18396.1 - 0.046 11.7 14.6 0.056 11.4 10.1 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein HAUS5 PF14817.1 ETO18396.1 - 0.048 12.2 10.5 0.062 11.8 7.2 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 DUF3405 PF11885.3 ETO18396.1 - 0.051 11.8 4.4 0.06 11.5 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) DUF2730 PF10805.3 ETO18396.1 - 0.055 13.2 2.9 0.078 12.7 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) APG6 PF04111.7 ETO18396.1 - 0.072 12.1 17.9 0.082 11.9 12.4 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Prominin PF05478.6 ETO18396.1 - 0.095 10.2 6.2 0.1 10.0 4.3 1.1 1 0 0 1 1 1 0 Prominin CR6_interact PF10147.4 ETO18396.1 - 0.12 11.6 12.6 0.14 11.4 8.7 1.2 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 IncA PF04156.9 ETO18396.1 - 0.13 11.8 13.9 0.18 11.3 9.6 1.3 1 0 0 1 1 1 0 IncA protein DUF2205 PF10224.4 ETO18396.1 - 0.16 11.5 10.8 0.54 9.8 7.2 2.1 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) Fzo_mitofusin PF04799.8 ETO18396.1 - 0.26 10.6 6.3 0.39 10.0 4.4 1.4 1 0 0 1 1 1 0 fzo-like conserved region CENP-Q PF13094.1 ETO18396.1 - 0.31 11.0 17.9 0.57 10.1 12.4 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit ADIP PF11559.3 ETO18396.1 - 0.34 10.8 19.0 0.38 10.6 12.8 1.3 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding TMCO5 PF14992.1 ETO18396.1 - 0.35 9.9 15.6 0.41 9.7 10.8 1.1 1 0 0 1 1 1 0 TMCO5 family DUF489 PF04356.7 ETO18396.1 - 0.35 10.4 5.0 0.45 10.0 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF489) UPF0449 PF15136.1 ETO18396.1 - 0.48 10.6 7.0 0.93 9.7 4.9 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 DUF342 PF03961.8 ETO18396.1 - 0.62 8.4 11.9 0.67 8.2 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) UPF0184 PF03670.8 ETO18396.1 - 0.82 9.8 6.3 0.21 11.8 1.7 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) AAA_11 PF13086.1 ETO18396.1 - 0.86 9.1 9.6 0.98 8.9 6.7 1.2 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 ETO18396.1 - 0.87 7.3 9.6 0.85 7.3 6.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ASD2 PF08687.6 ETO18396.1 - 1 8.6 14.3 0.91 8.7 9.5 1.3 1 1 0 1 1 1 0 Apx/Shroom domain ASD2 DUF1192 PF06698.6 ETO18396.1 - 1.1 9.1 4.5 3 7.7 3.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) DUF3373 PF11853.3 ETO18396.1 - 1.2 7.6 10.5 0.69 8.3 6.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) Allexi_40kDa PF05549.6 ETO18396.1 - 1.2 8.3 6.3 1.3 8.2 4.4 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein Atg14 PF10186.4 ETO18396.1 - 1.2 7.9 13.4 1.4 7.7 9.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SseC PF04888.7 ETO18396.1 - 1.3 8.2 8.6 2.1 7.6 6.0 1.4 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family SlyX PF04102.7 ETO18396.1 - 1.4 9.3 10.7 0.17 12.2 3.6 2.3 2 1 1 3 3 2 0 SlyX Snf7 PF03357.16 ETO18396.1 - 1.4 8.2 17.0 0.044 13.1 7.1 1.8 1 1 1 2 2 2 0 Snf7 ATG16 PF08614.6 ETO18396.1 - 1.5 8.5 21.1 0.49 10.1 12.2 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Med19 PF10278.4 ETO18396.1 - 1.5 8.4 12.5 0.23 11.1 5.8 1.6 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 PA26 PF04636.8 ETO18396.1 - 1.8 7.1 11.4 2 7.0 7.9 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) HDV_ag PF01517.13 ETO18396.1 - 2.1 7.9 9.3 2.8 7.5 6.4 1.4 1 1 0 1 1 1 0 Hepatitis delta virus delta antigen Uds1 PF15456.1 ETO18396.1 - 2.8 7.9 15.7 0.66 9.9 7.4 2.1 1 1 1 2 2 2 0 Up-regulated During Septation TMEM192 PF14802.1 ETO18396.1 - 3 6.6 6.2 4.3 6.1 4.3 1.3 1 0 0 1 1 1 0 TMEM192 family Sigma70_ner PF04546.8 ETO18396.1 - 3.3 7.2 14.8 0.2 11.2 7.0 1.4 2 0 0 2 2 1 0 Sigma-70, non-essential region ALMT PF11744.3 ETO18396.1 - 3.9 6.0 6.6 5.1 5.6 4.6 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter CCDC66 PF15236.1 ETO18396.1 - 4.9 6.7 23.5 0.65 9.6 13.3 1.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 66 SID-1_RNA_chan PF13965.1 ETO18396.1 - 5.6 5.0 7.2 6.1 4.8 5.0 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF3573 PF12097.3 ETO18396.1 - 6.1 5.3 7.3 6.8 5.2 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF4140 PF13600.1 ETO18396.1 - 6.6 7.2 8.0 15 6.1 5.6 1.7 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF4446 PF14584.1 ETO18396.1 - 7.7 6.3 11.0 5.1 6.9 6.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Exonuc_VII_L PF02601.10 ETO18396.1 - 7.9 5.5 14.5 9.1 5.3 10.0 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1049 PF06305.6 ETO18396.1 - 9.1 5.8 6.1 6 6.4 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1049) Glyco_tran_28_C PF04101.11 ETO18396.1 - 9.3 5.8 11.7 7 6.2 7.2 1.5 1 1 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain TMPIT PF07851.8 ETO18396.1 - 9.5 5.1 10.9 11 4.9 7.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein OmpH PF03938.9 ETO18396.1 - 9.8 6.0 16.6 14 5.6 11.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) zf-RING_2 PF13639.1 ETO18397.1 - 0.0036 17.0 5.0 0.01 15.6 3.5 1.9 1 0 0 1 1 1 1 Ring finger domain PP2 PF14299.1 ETO18397.1 - 0.035 13.4 2.1 2.7 7.3 0.1 2.6 2 0 0 2 2 2 0 Phloem protein 2 zf-RING_5 PF14634.1 ETO18397.1 - 0.62 9.8 5.2 1.6 8.5 3.3 2.0 1 1 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.2 ETO18397.1 - 2.3 8.3 7.9 15 5.7 5.5 2.4 1 1 0 1 1 1 0 RING-H2 zinc finger PWI PF01480.12 ETO18398.1 - 6.8e-18 64.5 0.7 3.9e-17 62.1 0.0 2.2 1 1 1 2 2 2 1 PWI domain Phage_AlpA PF05930.7 ETO18398.1 - 0.021 14.5 0.0 0.059 13.0 0.0 1.7 2 0 0 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) SLX9 PF15341.1 ETO18400.1 - 0.0071 16.7 7.7 0.0071 16.7 5.4 2.2 1 1 0 2 2 2 1 Ribosome biogenesis protein SLX9 BLVR PF06375.6 ETO18400.1 - 1.3 8.8 33.2 2.6 7.8 11.9 2.4 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Borrelia_P83 PF05262.6 ETO18400.1 - 2.5 6.2 24.7 2.6 6.2 17.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein MDFI PF15316.1 ETO18400.1 - 3 7.8 9.2 2.9 7.8 5.6 1.6 1 1 0 1 1 1 0 MyoD family inhibitor Amino_oxidase PF01593.19 ETO18401.1 - 9.3e-32 110.6 0.0 7.7e-29 101.0 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase SPX PF03105.14 ETO18401.1 - 0.0054 16.5 13.7 0.009 15.8 0.3 2.1 2 0 0 2 2 2 2 SPX domain DUF2201_N PF13203.1 ETO18401.1 - 0.16 11.1 13.7 0.02 14.0 2.4 2.1 2 0 0 2 2 2 0 Putative metallopeptidase domain Pex14_N PF04695.8 ETO18401.1 - 0.18 11.8 7.6 0.21 11.6 0.8 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CDC45 PF02724.9 ETO18401.1 - 6 4.7 12.6 1.3 6.9 0.3 2.0 2 0 0 2 2 2 0 CDC45-like protein DUF3037 PF11236.3 ETO18403.1 - 0.34 10.9 2.1 0.72 9.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) Arc_trans_TRASH PF08394.5 ETO18403.1 - 3 8.0 10.7 0.55 10.4 0.6 3.1 2 0 0 2 2 2 0 Archaeal TRASH domain EphA2_TM PF14575.1 ETO18404.1 - 0.3 11.5 1.5 0.82 10.1 0.1 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DSHCT PF08148.7 ETO18404.1 - 0.42 9.8 4.5 0.14 11.4 0.7 1.8 1 1 0 2 2 2 0 DSHCT (NUC185) domain Cauli_AT PF03233.8 ETO18404.1 - 1.1 8.9 14.3 0.13 11.9 6.4 1.9 2 0 0 2 2 2 0 Aphid transmission protein DUF4220 PF13968.1 ETO18404.1 - 2.8 6.9 8.2 3.9 6.4 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) LRR_6 PF13516.1 ETO18405.1 - 3.7e-08 32.6 11.8 0.11 12.6 0.0 5.9 5 0 0 5 5 5 4 Leucine Rich repeat LRR_4 PF12799.2 ETO18405.1 - 8.4e-07 28.4 5.5 0.0021 17.6 0.1 3.7 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETO18405.1 - 0.00052 19.6 5.1 55 4.3 0.0 5.9 5 0 0 5 5 5 0 Leucine Rich Repeat CENP-T PF15511.1 ETO18405.1 - 1.5 7.9 41.5 0.036 13.3 17.0 2.3 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T UPF1_Zn_bind PF09416.5 ETO18406.1 - 2.2e-08 33.8 0.0 5.1e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) PUF PF00806.14 ETO18407.1 - 3.9e-26 89.0 8.2 4.3e-06 25.8 0.0 6.4 6 0 0 6 6 6 6 Pumilio-family RNA binding repeat Fels1 PF05666.6 ETO18407.1 - 0.89 8.9 3.8 4.6 6.6 0.3 3.0 3 0 0 3 3 3 0 Fels-1 Prophage Protein-like NIPSNAP PF07978.8 ETO18408.1 - 0.00098 19.0 0.0 0.0025 17.7 0.0 1.7 1 0 0 1 1 1 1 NIPSNAP DUF1157 PF06636.6 ETO18410.1 - 0.017 13.7 0.7 0.017 13.7 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1157) ABC_membrane PF00664.18 ETO18411.1 - 2.4e-37 128.8 14.1 1.3e-35 123.1 9.8 2.5 1 1 0 1 1 1 1 ABC transporter transmembrane region DUF2207 PF09972.4 ETO18411.1 - 0.036 12.6 0.1 0.036 12.6 0.1 1.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) SAM_2 PF07647.12 ETO18412.1 - 2e-12 46.7 0.1 3.9e-12 45.8 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO18412.1 - 6.7e-11 42.2 0.1 1.5e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 ETO18412.1 - 1.9e-06 28.0 1.1 1.9e-06 28.0 0.8 3.0 2 1 0 2 2 2 1 PH domain SAM_PNT PF02198.11 ETO18412.1 - 0.014 15.1 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain PH_8 PF15409.1 ETO18412.1 - 0.024 14.6 0.1 0.024 14.6 0.0 2.8 3 0 0 3 3 3 0 Pleckstrin homology domain RNase_PH_C PF03725.10 ETO18413.1 - 4e-13 49.0 0.0 6.8e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 RNase_PH PF01138.16 ETO18413.1 - 0.00079 19.7 0.2 0.0047 17.2 0.0 2.2 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 Maf1 PF09174.5 ETO18413.1 - 0.045 13.6 1.0 0.061 13.1 0.7 1.2 1 0 0 1 1 1 0 Maf1 regulator PNPase PF03726.9 ETO18413.1 - 0.045 14.0 0.1 0.14 12.4 0.0 1.9 1 1 1 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain SR-25 PF10500.4 ETO18416.1 - 0.012 15.0 7.3 0.012 15.0 5.1 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein YqfQ PF14181.1 ETO18416.1 - 0.023 14.7 0.8 0.023 14.7 0.6 2.8 3 0 0 3 3 3 0 YqfQ-like protein Tom37_C PF11801.3 ETO18416.1 - 4 7.2 5.7 6.6 6.5 0.2 2.2 2 0 0 2 2 2 0 Tom37 C-terminal domain PBP1_TM PF14812.1 ETO18416.1 - 4.2 7.7 11.5 4.6 7.6 2.2 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Zip PF02535.17 ETO18417.1 - 4.3 6.2 7.7 0.08 11.9 0.6 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter Mem_trans PF03547.13 ETO18418.1 - 0.015 13.5 3.8 0.019 13.2 2.6 1.1 1 0 0 1 1 1 0 Membrane transport protein CDC45 PF02724.9 ETO18418.1 - 0.034 12.1 6.8 0.039 12.0 4.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.11 ETO18418.1 - 0.15 11.9 2.8 0.18 11.6 2.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region eIF-3c_N PF05470.7 ETO18418.1 - 0.61 8.0 12.8 0.7 7.9 8.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Myc_N PF01056.13 ETO18418.1 - 0.63 9.1 6.4 0.79 8.8 4.5 1.2 1 0 0 1 1 1 0 Myc amino-terminal region BSP_II PF05432.6 ETO18418.1 - 1.4 8.1 11.8 4.2 6.5 8.2 1.6 1 1 0 1 1 1 0 Bone sialoprotein II (BSP-II) RNA_pol_Rpb1_5 PF04998.12 ETO18418.1 - 2.7 7.1 7.4 3.6 6.7 5.1 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 AAA_18 PF13238.1 ETO18419.1 - 2e-07 31.3 1.6 3.7e-07 30.4 1.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO18419.1 - 3e-06 28.0 0.0 2.5e-05 25.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETO18419.1 - 2.3e-05 24.3 0.1 4.8e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 ETO18419.1 - 2.5e-05 24.5 0.3 3.6e-05 24.0 0.2 1.2 1 0 0 1 1 1 1 ABC transporter RNA_helicase PF00910.17 ETO18419.1 - 6.9e-05 22.9 2.0 0.006 16.7 1.0 2.9 2 1 0 2 2 2 1 RNA helicase NACHT PF05729.7 ETO18419.1 - 0.00041 20.0 0.0 0.00099 18.7 0.0 1.7 2 0 0 2 2 2 1 NACHT domain ATP_bind_1 PF03029.12 ETO18419.1 - 0.0006 19.4 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Viral_helicase1 PF01443.13 ETO18419.1 - 0.00085 18.9 0.0 0.0016 17.9 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase FtsK_SpoIIIE PF01580.13 ETO18419.1 - 0.0014 18.0 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family NB-ARC PF00931.17 ETO18419.1 - 0.002 17.0 0.0 0.0043 15.9 0.0 1.5 2 0 0 2 2 2 1 NB-ARC domain cobW PF02492.14 ETO18419.1 - 0.002 17.5 0.0 0.0032 16.9 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 ETO18419.1 - 0.0026 17.1 0.0 0.0049 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 ETO18419.1 - 0.0027 17.2 0.0 0.0076 15.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 ETO18419.1 - 0.003 17.6 0.0 0.0051 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 ETO18419.1 - 0.0032 17.3 0.1 0.0082 16.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETO18419.1 - 0.0033 17.4 0.0 0.0047 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 ETO18419.1 - 0.0034 16.5 0.0 0.042 12.9 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_10 PF12846.2 ETO18419.1 - 0.0043 16.5 0.0 0.0069 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain MobB PF03205.9 ETO18419.1 - 0.0049 16.5 0.0 0.012 15.2 0.0 1.7 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 ETO18419.1 - 0.0092 15.7 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 NTPase ADK PF00406.17 ETO18419.1 - 0.0098 15.7 0.0 0.21 11.4 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase AAA PF00004.24 ETO18419.1 - 0.012 15.7 0.0 0.03 14.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 ETO18419.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Dynamin_N PF00350.18 ETO18419.1 - 0.018 14.8 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Dynamin family AAA_19 PF13245.1 ETO18419.1 - 0.02 14.6 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain ArgK PF03308.11 ETO18419.1 - 0.024 13.4 0.0 0.035 12.8 0.0 1.2 1 0 0 1 1 1 0 ArgK protein DUF258 PF03193.11 ETO18419.1 - 0.031 13.4 0.0 0.048 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Miro PF08477.8 ETO18419.1 - 0.042 14.3 0.0 0.08 13.4 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein TT_ORF1 PF02956.9 ETO18419.1 - 0.051 12.0 2.1 0.059 11.8 1.4 1.0 1 0 0 1 1 1 0 TT viral orf 1 Menin PF05053.8 ETO18419.1 - 0.052 11.7 0.4 0.053 11.6 0.3 1.1 1 0 0 1 1 1 0 Menin KTI12 PF08433.5 ETO18419.1 - 0.058 12.6 0.0 0.058 12.6 0.0 1.5 2 0 0 2 2 1 0 Chromatin associated protein KTI12 AAA_5 PF07728.9 ETO18419.1 - 0.085 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Daxx PF03344.10 ETO18419.1 - 0.1 11.0 10.0 0.13 10.6 6.9 1.2 1 0 0 1 1 1 0 Daxx Family AAA_28 PF13521.1 ETO18419.1 - 0.13 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain CPT PF07931.7 ETO18419.1 - 0.16 11.6 0.9 0.64 9.6 0.1 2.2 2 1 1 3 3 3 0 Chloramphenicol phosphotransferase-like protein RRN3 PF05327.6 ETO18419.1 - 0.2 9.7 2.3 0.24 9.4 1.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.9 ETO18419.1 - 0.35 8.8 6.7 0.42 8.6 4.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 ETO18419.1 - 1.4 7.5 21.8 1.8 7.1 15.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Macoilin PF09726.4 ETO18419.1 - 5.1 5.2 7.9 6.1 4.9 5.5 1.0 1 0 0 1 1 1 0 Transmembrane protein Nop25 PF09805.4 ETO18419.1 - 5.5 7.0 8.2 8.1 6.5 5.7 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) CobT PF06213.7 ETO18419.1 - 7.3 5.6 13.8 9.8 5.2 9.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sigma70_ner PF04546.8 ETO18420.1 - 0.00025 20.7 3.9 0.00057 19.5 2.7 1.6 1 0 0 1 1 1 1 Sigma-70, non-essential region Lipase_3 PF01764.20 ETO18420.1 - 0.002 17.7 0.1 0.0068 16.0 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) DUF2457 PF10446.4 ETO18420.1 - 0.0088 14.8 13.6 0.012 14.3 9.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Vfa1 PF08432.5 ETO18420.1 - 0.031 14.3 1.2 0.031 14.3 0.9 1.5 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 RXT2_N PF08595.6 ETO18420.1 - 0.16 11.7 5.9 0.38 10.5 4.1 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF3245 PF11595.3 ETO18420.1 - 0.36 11.0 8.4 0.74 10.0 5.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) LAT PF15234.1 ETO18420.1 - 0.36 10.2 2.7 0.54 9.6 1.9 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells RNA_pol_3_Rpc31 PF11705.3 ETO18420.1 - 0.48 10.3 13.8 0.85 9.5 9.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.5 ETO18420.1 - 0.55 10.4 13.0 1.3 9.2 9.0 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RRN3 PF05327.6 ETO18420.1 - 0.61 8.1 3.0 0.88 7.6 2.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FAM176 PF14851.1 ETO18420.1 - 0.7 9.5 2.9 1.5 8.4 2.0 1.6 1 0 0 1 1 1 0 FAM176 family Daxx PF03344.10 ETO18420.1 - 0.7 8.3 8.2 0.9 7.9 5.7 1.1 1 0 0 1 1 1 0 Daxx Family PBP1_TM PF14812.1 ETO18420.1 - 0.77 10.0 14.5 0.25 11.6 7.9 1.8 2 0 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.7 ETO18420.1 - 0.88 7.4 10.5 1.2 7.0 7.2 1.1 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.7 ETO18420.1 - 1 8.4 10.7 1.5 7.8 7.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.7 ETO18420.1 - 1.1 8.5 10.2 1.6 7.8 7.1 1.2 1 0 0 1 1 1 0 NOA36 protein Tom22 PF04281.8 ETO18420.1 - 1.3 8.5 8.5 2.7 7.5 5.9 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Nucleoplasmin PF03066.10 ETO18420.1 - 1.5 8.2 13.6 3 7.3 9.4 1.4 1 0 0 1 1 1 0 Nucleoplasmin Bd3614_N PF14442.1 ETO18420.1 - 4.5 7.2 7.6 7.6 6.5 5.2 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal CDC45 PF02724.9 ETO18420.1 - 9.3 4.1 9.6 3.1 5.7 5.0 1.3 2 0 0 2 2 2 0 CDC45-like protein DUF1624 PF07786.7 ETO18421.1 - 0.057 12.7 0.1 0.071 12.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1624) Med14 PF08638.6 ETO18422.1 - 0.0025 17.0 2.5 0.0037 16.5 1.7 1.2 1 0 0 1 1 1 1 Mediator complex subunit MED14 FNIP_M PF14637.1 ETO18422.1 - 0.0063 16.1 1.7 0.01 15.4 1.2 1.3 1 0 0 1 1 1 1 Folliculin-interacting protein middle domain RVT_3 PF13456.1 ETO18422.1 - 0.054 13.2 0.2 2.6 7.8 0.0 2.5 2 0 0 2 2 2 0 Reverse transcriptase-like Pup PF05639.6 ETO18422.1 - 0.097 13.1 0.8 0.097 13.1 0.6 2.5 2 1 0 2 2 2 0 Pup-like protein CLTH PF10607.4 ETO18422.1 - 0.35 10.5 2.9 0.39 10.4 1.2 1.8 1 1 1 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain WD40 PF00400.27 ETO18423.1 - 1.4e-09 37.4 2.2 7.4e-09 35.1 0.8 2.6 3 0 0 3 3 3 1 WD domain, G-beta repeat zf-RING_2 PF13639.1 ETO18423.1 - 0.0012 18.5 1.1 0.0051 16.6 0.8 2.1 1 0 0 1 1 1 1 Ring finger domain ADIP PF11559.3 ETO18423.1 - 0.0014 18.5 17.2 0.0014 18.5 11.9 3.3 3 1 0 3 3 3 1 Afadin- and alpha -actinin-Binding DUF1743 PF08489.6 ETO18423.1 - 0.0086 15.8 1.1 0.02 14.6 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1743) DUF4164 PF13747.1 ETO18423.1 - 0.017 15.2 1.0 0.017 15.2 0.7 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) zf-BED PF02892.10 ETO18423.1 - 0.29 10.9 5.2 0.68 9.7 0.1 3.2 3 0 0 3 3 3 0 BED zinc finger ERM PF00769.14 ETO18423.1 - 1 8.8 26.1 1.7 8.1 18.1 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Rootletin PF15035.1 ETO18423.1 - 2.3 8.1 30.0 0.13 12.1 10.9 2.4 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Med4 PF10018.4 ETO18423.1 - 5.9 6.2 18.2 0.13 11.6 7.0 2.2 1 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Reo_sigmaC PF04582.7 ETO18423.1 - 9.4 5.3 8.7 12 4.9 4.4 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein WD40 PF00400.27 ETO18424.1 - 8.7e-39 130.0 12.2 1.1e-11 44.0 1.3 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO18424.1 - 1.2e-08 33.5 1.2 0.00057 18.1 0.3 2.4 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO18424.1 - 0.00081 18.2 5.2 0.076 11.7 1.4 2.2 1 1 1 2 2 2 2 Nup133 N terminal like zf-TRAF PF02176.13 ETO18425.1 - 2.6e-05 24.4 3.7 2.6e-05 24.4 2.6 2.2 2 0 0 2 2 2 1 TRAF-type zinc finger RNB PF00773.14 ETO18425.1 - 0.021 14.1 0.3 0.026 13.7 0.2 1.1 1 0 0 1 1 1 0 RNB domain WD40 PF00400.27 ETO18426.1 - 4.9e-32 108.6 11.9 2e-10 40.1 0.0 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO18426.1 - 1.4e-09 36.6 5.9 0.00069 17.8 0.6 3.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Cu-oxidase_2 PF07731.9 ETO18426.1 - 0.01 15.3 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Multicopper oxidase DUF1914 PF08932.5 ETO18426.1 - 0.082 12.9 0.5 17 5.4 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1914) Ig_2 PF13895.1 ETO18426.1 - 1.4 9.1 4.3 1.5 9.0 0.9 2.4 2 1 0 2 2 2 0 Immunoglobulin domain Ras PF00071.17 ETO18427.1 - 1.8e-05 24.2 0.0 0.00021 20.7 0.1 2.1 2 0 0 2 2 2 1 Ras family Miro PF08477.8 ETO18427.1 - 0.073 13.5 0.0 0.42 11.1 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein Rad4 PF03835.10 ETO18429.1 - 0.039 13.3 8.7 0.17 11.3 6.0 1.8 1 1 0 1 1 1 0 Rad4 transglutaminase-like domain ECSIT PF06239.6 ETO18429.1 - 0.59 8.9 8.0 0.66 8.8 5.5 1.0 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway AIF_C PF14721.1 ETO18429.1 - 1.1 9.5 6.4 1.3 9.2 4.4 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term YfhO PF09586.5 ETO18429.1 - 1.2 7.0 8.3 1.3 6.9 5.7 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DDHD PF02862.12 ETO18429.1 - 1.3 8.7 5.3 1.4 8.6 3.7 1.0 1 0 0 1 1 1 0 DDHD domain PDCD2_C PF04194.8 ETO18429.1 - 1.6 8.2 6.6 1.8 8.1 4.6 1.0 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain RE_AlwI PF09491.5 ETO18429.1 - 1.7 7.0 10.8 2 6.7 7.5 1.0 1 0 0 1 1 1 0 AlwI restriction endonuclease GAGA_bind PF06217.7 ETO18429.1 - 1.8 8.4 9.5 1.9 8.3 6.6 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.7 ETO18429.1 - 2.6 7.8 7.8 3.1 7.6 5.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3464 PF11947.3 ETO18429.1 - 3.2 7.2 7.9 3.7 7.0 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF4407 PF14362.1 ETO18429.1 - 3.6 6.4 7.2 4.3 6.2 5.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2500 PF10694.4 ETO18429.1 - 4.6 7.2 8.1 5.6 7.0 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) Sec62 PF03839.11 ETO18429.1 - 5.6 6.2 11.9 6.1 6.1 8.2 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4604 PF15377.1 ETO18429.1 - 7.4 6.7 19.1 8.6 6.5 13.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Pkinase PF00069.20 ETO18430.1 - 2e-53 181.2 0.0 1.2e-52 178.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO18430.1 - 3.7e-23 81.9 0.2 7.9e-23 80.8 0.2 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Myosin_TH1 PF06017.8 ETO18430.1 - 9.5e-08 31.5 1.2 1.6e-07 30.8 0.2 1.9 2 0 0 2 2 2 1 Myosin tail Kdo PF06293.9 ETO18430.1 - 0.0016 17.5 0.1 0.0042 16.1 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETO18430.1 - 0.0052 15.7 0.1 0.09 11.7 0.0 2.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 ETO18430.1 - 0.017 14.9 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF943 PF06092.7 ETO18430.1 - 0.024 13.9 1.3 0.053 12.8 0.9 1.5 1 0 0 1 1 1 0 Enterobacterial putative membrane protein (DUF943) Pkinase_C PF00433.19 ETO18430.1 - 0.03 14.8 3.5 0.077 13.5 2.5 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain GDPD PF03009.12 ETO18431.1 - 4.4e-29 101.7 0.0 6.2e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD PF03009.12 ETO18432.1 - 5e-12 45.8 0.1 1e-10 41.5 0.0 2.2 2 1 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family Inhibitor_I71 PF12628.2 ETO18433.1 - 0.084 12.5 0.3 0.14 11.7 0.2 1.3 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor Ank_2 PF12796.2 ETO18434.1 - 1.3e-30 105.5 2.2 1.3e-09 38.2 0.2 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETO18434.1 - 1.2e-28 97.4 0.8 7.5e-07 28.6 0.0 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 ETO18434.1 - 5e-25 86.9 3.5 5e-10 39.2 0.0 4.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO18434.1 - 1.3e-24 83.7 2.0 0.0001 22.1 0.0 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 ETO18434.1 - 3.5e-24 84.7 1.8 6.2e-11 42.5 0.0 4.2 3 1 1 4 4 4 4 Ankyrin repeats (many copies) CBM_20 PF00686.14 ETO18434.1 - 6.3e-11 41.7 0.0 1.7e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Starch binding domain DUF3447 PF11929.3 ETO18434.1 - 0.0046 16.7 1.4 0.013 15.2 0.3 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF3447) IncA PF04156.9 ETO18438.1 - 0.0047 16.5 1.3 0.0047 16.5 0.9 2.0 3 0 0 3 3 3 1 IncA protein CDC27 PF09507.5 ETO18438.1 - 1.3 8.1 37.6 1.9 7.5 26.0 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2951 PF11166.3 ETO18439.1 - 0.19 11.5 0.1 0.19 11.5 0.1 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2951) TPR_12 PF13424.1 ETO18440.1 - 9.3e-37 124.8 8.2 6.1e-15 54.9 0.0 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO18440.1 - 1.1e-21 76.2 12.5 4.2e-13 48.7 0.7 3.1 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETO18440.1 - 2.2e-21 74.5 17.0 3.5e-09 35.8 0.3 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO18440.1 - 6.2e-19 66.2 0.3 3.2e-05 23.4 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO18440.1 - 1.6e-17 61.9 11.6 8.9e-05 22.1 0.1 5.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO18440.1 - 6.6e-16 57.6 0.0 2.3e-05 24.1 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO18440.1 - 1.2e-13 49.8 15.6 9.9e-06 24.9 0.2 4.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO18440.1 - 7.4e-07 29.2 0.0 0.041 14.5 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO18440.1 - 5.8e-06 26.1 1.5 0.66 10.3 0.0 4.5 4 1 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO18440.1 - 9.1e-06 25.7 6.4 5.1e-05 23.3 1.1 3.0 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO18440.1 - 6.8e-05 23.1 0.0 0.0047 17.2 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO18440.1 - 0.00011 22.7 0.0 0.022 15.4 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF2225 PF09986.4 ETO18440.1 - 0.00046 19.6 3.3 0.012 15.0 0.1 2.7 1 1 2 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_6 PF13174.1 ETO18440.1 - 0.00066 19.9 1.7 16 6.2 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat PPR PF01535.15 ETO18440.1 - 0.018 14.9 0.5 2.4 8.3 0.0 3.8 3 0 0 3 3 3 0 PPR repeat WD40 PF00400.27 ETO18441.1 - 8.8e-69 225.1 21.4 5.4e-14 51.4 0.1 7.4 7 1 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO18441.1 - 4e-16 59.3 0.1 3.9e-08 33.2 0.0 3.3 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO18441.1 - 1.9e-05 23.1 2.5 0.1 10.8 0.0 3.5 1 1 2 4 4 4 3 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO18441.1 - 0.00021 20.1 12.8 0.8 8.3 0.9 5.5 1 1 3 5 5 5 3 Nup133 N terminal like Hira PF07569.6 ETO18441.1 - 0.0023 17.1 0.6 7.3 5.7 0.0 4.2 3 1 1 5 5 5 2 TUP1-like enhancer of split BBS2_Mid PF14783.1 ETO18441.1 - 0.0031 17.2 1.4 9.2 6.0 0.0 4.5 3 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region DUF1258 PF06869.7 ETO18441.1 - 0.009 15.1 0.2 0.83 8.6 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1258) DPPIV_N PF00930.16 ETO18441.1 - 0.017 13.7 0.6 1.1 7.8 0.2 3.8 2 2 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Germane PF10646.4 ETO18441.1 - 0.022 14.9 0.0 2.1 8.5 0.0 2.7 2 0 0 2 2 2 0 Sporulation and spore germination DUF1064 PF06356.6 ETO18441.1 - 0.041 13.8 0.2 0.5 10.3 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1064) PD40 PF07676.7 ETO18441.1 - 0.042 13.5 8.4 2.4 7.9 0.1 5.2 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat DUF3732 PF12532.3 ETO18441.1 - 0.12 11.8 0.2 50 3.3 0.0 3.9 2 2 2 4 4 4 0 Protein of unknown function (DUF3732) Asparaginase PF00710.15 ETO18442.1 - 3.7e-41 140.9 0.0 1.5e-40 139.0 0.0 1.9 2 1 0 2 2 2 1 Asparaginase CDC45 PF02724.9 ETO18442.1 - 3.4e-05 22.1 16.6 3.4e-05 22.1 11.5 2.3 2 0 0 2 2 2 1 CDC45-like protein DUF1510 PF07423.6 ETO18442.1 - 0.00015 21.1 17.7 0.00015 21.1 12.3 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1510) Ycf1 PF05758.7 ETO18442.1 - 0.17 9.5 9.8 0.027 12.2 0.5 2.2 2 0 0 2 2 2 0 Ycf1 Nop14 PF04147.7 ETO18442.1 - 0.31 8.9 44.4 0.02 12.8 26.4 1.9 2 0 0 2 2 2 0 Nop14-like family Kelch_6 PF13964.1 ETO18446.1 - 2.6e-07 30.5 1.2 0.0066 16.5 0.0 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 ETO18446.1 - 0.005 16.3 1.6 13 5.4 0.0 3.5 3 0 0 3 3 3 2 Kelch motif HPS3_Mid PF14762.1 ETO18446.1 - 0.02 13.5 0.5 0.029 12.9 0.3 1.2 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3, middle region Kelch_5 PF13854.1 ETO18446.1 - 0.021 14.7 1.0 3.3 7.7 0.1 3.5 4 0 0 4 4 4 0 Kelch motif Arf PF00025.16 ETO18447.1 - 1.1e-61 207.0 0.2 7.2e-37 126.3 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.5 ETO18447.1 - 1.9e-07 30.4 0.0 0.0098 15.1 0.0 2.3 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit Ras PF00071.17 ETO18447.1 - 1.7e-05 24.2 0.0 0.14 11.5 0.1 2.2 2 0 0 2 2 2 2 Ras family Miro PF08477.8 ETO18447.1 - 2.3e-05 24.8 0.1 0.003 18.0 0.0 2.4 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 ETO18447.1 - 5.3e-05 23.1 0.0 8.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 ETO18447.1 - 0.0004 19.5 0.3 0.01 14.9 0.0 2.1 1 1 0 2 2 2 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 ETO18447.1 - 0.0011 17.7 0.7 6.1 5.4 0.1 3.2 2 1 1 3 3 3 3 G-protein alpha subunit AAA_33 PF13671.1 ETO18447.1 - 0.063 13.1 0.1 0.38 10.6 0.1 2.2 1 1 0 1 1 1 0 AAA domain EHN PF06441.7 ETO18448.1 - 2.6e-19 69.1 0.9 4.1e-19 68.5 0.6 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 ETO18448.1 - 0.0032 17.3 0.0 0.0081 16.0 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Herpes_UL92 PF03048.9 ETO18448.1 - 0.099 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 UL92 family PTEN_C2 PF10409.4 ETO18451.1 - 1.9e-05 24.3 1.1 6.2e-05 22.7 0.7 2.1 1 1 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein CDC45 PF02724.9 ETO18452.1 - 0.17 9.9 12.8 0.27 9.2 8.9 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 ETO18452.1 - 1.3 7.6 25.9 2.9 6.5 18.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TRAP_alpha PF03896.11 ETO18452.1 - 6.2 5.7 12.3 1.6 7.6 5.9 1.8 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Sporozoite_P67 PF05642.6 ETO18452.1 - 9.6 3.9 8.6 14 3.4 5.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ELMO_CED12 PF04727.8 ETO18453.1 - 4.2e-19 68.7 1.0 2.1e-18 66.4 0.7 2.1 1 1 0 1 1 1 1 ELMO/CED-12 family Ribosomal_60s PF00428.14 ETO18454.1 - 1.2e-13 51.2 1.8 1.4e-13 50.9 1.3 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ion_trans PF00520.26 ETO18456.1 - 5.1e-24 84.6 34.2 6.3e-21 74.5 19.9 3.6 3 1 0 3 3 3 2 Ion transport protein DUF3452 PF11934.3 ETO18457.1 - 0.0042 16.3 0.0 0.0073 15.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3452) DUF4611 PF15387.1 ETO18458.1 - 0.029 14.4 0.1 0.05 13.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF4046 PF13255.1 ETO18459.1 - 0.004 15.9 1.1 0.75 8.4 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF4046) Retrotrans_gag PF03732.12 ETO18459.1 - 0.016 15.2 0.5 1.4 9.0 0.0 2.8 2 1 1 3 3 3 0 Retrotransposon gag protein Herpes_UL6 PF01763.11 ETO18459.1 - 0.037 12.2 0.2 0.048 11.8 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF1410 PF07198.6 ETO18459.1 - 0.067 13.5 2.9 0.13 12.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1410) SPRY PF00622.23 ETO18460.1 - 1.2e-07 31.8 0.0 1.5e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 SPRY domain G-alpha PF00503.15 ETO18461.1 - 4.5e-34 117.7 13.5 2.5e-31 108.7 3.1 2.1 2 0 0 2 2 2 2 G-protein alpha subunit Arf PF00025.16 ETO18461.1 - 3e-08 33.1 1.4 4.2e-06 26.1 0.3 2.3 1 1 1 2 2 2 2 ADP-ribosylation factor family Daxx PF03344.10 ETO18462.1 - 0.0088 14.5 24.0 0.012 14.1 16.6 1.2 1 0 0 1 1 1 1 Daxx Family TPR_2 PF07719.12 ETO18462.1 - 0.0089 15.8 0.0 0.027 14.3 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO18462.1 - 0.022 15.3 0.9 0.15 12.7 0.0 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat Nucleoplasmin PF03066.10 ETO18462.1 - 0.24 10.9 17.0 0.51 9.8 11.8 1.7 1 0 0 1 1 1 0 Nucleoplasmin PI3K_1B_p101 PF10486.4 ETO18462.1 - 0.26 8.7 8.7 0.33 8.4 6.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Sporozoite_P67 PF05642.6 ETO18462.1 - 0.49 8.1 14.0 0.64 7.8 9.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ycf1 PF05758.7 ETO18462.1 - 2.5 5.7 14.3 3 5.4 9.9 1.2 1 0 0 1 1 1 0 Ycf1 Neur_chan_memb PF02932.11 ETO18462.1 - 2.6 7.8 4.7 4 7.2 3.3 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MIP-T3 PF10243.4 ETO18462.1 - 2.7 6.3 31.7 3.8 5.8 22.0 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 GAGA_bind PF06217.7 ETO18462.1 - 2.8 7.8 8.0 3.5 7.5 5.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DARPP-32 PF05395.7 ETO18462.1 - 3 7.9 19.3 4.9 7.2 13.4 1.3 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Spt5_N PF11942.3 ETO18462.1 - 3.7 8.2 28.4 1.9 9.1 17.6 2.2 2 0 0 2 2 1 0 Spt5 transcription elongation factor, acidic N-terminal Herpes_DNAp_acc PF04929.7 ETO18462.1 - 3.9 6.3 10.6 5 5.9 7.3 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF4175 PF13779.1 ETO18462.1 - 4.2 4.9 17.3 0.15 9.7 8.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) CDC45 PF02724.9 ETO18462.1 - 5.7 4.8 26.0 7.8 4.3 17.7 1.3 1 1 0 1 1 1 0 CDC45-like protein DUF2890 PF11081.3 ETO18462.1 - 5.8 6.9 21.2 9.9 6.1 14.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Prog_receptor PF02161.10 ETO18462.1 - 6.2 5.5 9.2 8.4 5.0 6.4 1.2 1 0 0 1 1 1 0 Progesterone receptor TRAP_alpha PF03896.11 ETO18462.1 - 7.6 5.4 14.1 12 4.8 9.8 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PLRV_ORF5 PF01690.12 ETO18462.1 - 8.2 5.4 16.2 11 4.9 11.2 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Sox_N PF12444.3 ETO18462.1 - 8.2 7.6 0.0 8.2 7.6 0.0 3.4 2 1 0 2 2 1 0 Sox developmental protein N terminal PRTP PF01366.13 ETO18462.1 - 9.5 4.0 13.5 16 3.3 9.4 1.4 1 1 0 1 1 1 0 Herpesvirus processing and transport protein DUF1900 PF08954.6 ETO18464.1 - 1.4e-47 160.5 0.0 2.2e-47 159.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) Ctf8 PF09696.5 ETO18464.1 - 8.9e-05 22.2 3.1 0.00016 21.4 2.1 1.4 1 0 0 1 1 1 1 Ctf8 HALZ PF02183.13 ETO18464.1 - 0.0047 16.6 0.2 0.0087 15.7 0.1 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper DUF972 PF06156.8 ETO18464.1 - 0.43 10.9 7.9 0.79 10.0 5.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) PA26 PF04636.8 ETO18464.1 - 0.53 8.9 6.3 0.77 8.3 4.4 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) WD40 PF00400.27 ETO18466.1 - 2e-75 246.1 29.4 1.6e-12 46.7 0.1 10.3 10 1 0 10 10 10 8 WD domain, G-beta repeat Nup160 PF11715.3 ETO18466.1 - 8.2e-11 40.7 6.0 0.042 11.9 0.1 5.9 4 1 0 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO18466.1 - 0.0051 15.6 18.8 0.16 10.6 2.8 4.6 2 2 2 4 4 4 2 Nup133 N terminal like DUF1664 PF07889.7 ETO18467.1 - 0.012 15.4 0.3 0.027 14.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SDA1 PF05285.7 ETO18467.1 - 0.16 11.2 22.9 0.21 10.8 15.9 1.1 1 0 0 1 1 1 0 SDA1 Cep57_MT_bd PF06657.8 ETO18467.1 - 0.3 11.0 3.5 5.3 7.0 0.5 3.0 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Tim54 PF11711.3 ETO18467.1 - 0.36 9.3 7.6 0.62 8.6 5.2 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Zip PF02535.17 ETO18467.1 - 0.36 9.7 3.7 0.45 9.4 2.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Raftlin PF15250.1 ETO18467.1 - 0.46 8.9 9.5 0.69 8.3 6.6 1.3 1 0 0 1 1 1 0 Raftlin Menin PF05053.8 ETO18467.1 - 0.49 8.5 10.4 0.61 8.1 7.2 1.1 1 0 0 1 1 1 0 Menin CENP-T PF15511.1 ETO18467.1 - 0.51 9.5 11.0 0.68 9.1 7.6 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T SID-1_RNA_chan PF13965.1 ETO18467.1 - 0.66 8.0 6.0 0.84 7.7 4.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Nop14 PF04147.7 ETO18467.1 - 0.78 7.5 25.1 0.11 10.3 14.0 1.8 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.9 ETO18467.1 - 1.4 6.8 19.3 2 6.3 13.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 ETO18467.1 - 1.5 7.1 24.4 2 6.7 16.9 1.1 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 ETO18467.1 - 2.7 6.6 24.7 3.8 6.1 17.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RP-C_C PF11800.3 ETO18467.1 - 3.3 7.3 10.8 3.7 7.1 6.8 1.7 2 0 0 2 2 2 0 Replication protein C C-terminal region DUF1510 PF07423.6 ETO18467.1 - 4 6.7 30.2 5.8 6.2 20.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) AAA_5 PF07728.9 ETO18468.1 - 0.003 17.3 0.0 0.005 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_8 PF12780.2 ETO18469.1 - 2.8e-57 193.7 1.2 5.3e-57 192.8 0.3 1.8 1 1 1 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 ETO18469.1 - 7.4e-47 159.7 0.4 3.8e-45 154.0 0.1 2.6 2 1 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_16 PF13191.1 ETO18469.1 - 6.9e-07 29.4 0.0 0.028 14.3 0.0 4.2 3 1 1 4 4 4 1 AAA ATPase domain AAA_5 PF07728.9 ETO18469.1 - 1.9e-06 27.6 0.0 0.00046 19.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETO18469.1 - 0.00025 21.2 0.0 0.0082 16.2 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA PF00004.24 ETO18469.1 - 0.00028 21.0 0.1 1 9.5 0.0 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 ETO18469.1 - 0.015 16.1 0.1 19 6.0 0.0 3.3 4 1 0 4 4 3 0 AAA domain AAA_19 PF13245.1 ETO18469.1 - 0.02 14.6 0.0 0.097 12.4 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain T2SE PF00437.15 ETO18469.1 - 0.022 13.6 0.0 0.097 11.5 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF815 PF05673.8 ETO18469.1 - 0.03 13.2 0.0 7.6 5.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 ETO18469.1 - 0.04 13.4 0.0 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain IL6Ra-bind PF09240.5 ETO18469.1 - 0.051 13.7 2.1 1.1 9.4 0.0 3.3 3 1 1 4 4 3 0 Interleukin-6 receptor alpha chain, binding PRK PF00485.13 ETO18469.1 - 0.064 12.8 0.1 3.2 7.2 0.0 2.9 2 1 1 3 3 3 0 Phosphoribulokinase / Uridine kinase family MobB PF03205.9 ETO18469.1 - 0.13 11.9 0.0 0.4 10.3 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MT PF12777.2 ETO18470.1 - 1.8e-20 73.0 8.5 2.1e-20 72.7 5.9 1.1 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor DUF948 PF06103.6 ETO18470.1 - 0.00014 21.6 2.9 0.00042 20.1 2.0 1.9 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) Staphylokinase PF02821.11 ETO18470.1 - 0.014 15.1 0.5 0.014 15.1 0.4 2.0 2 0 0 2 2 2 0 Staphylokinase/Streptokinase family AAA_8 PF12780.2 ETO18470.1 - 0.082 11.8 0.5 0.2 10.5 0.3 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 Flagellin_C PF00700.16 ETO18470.1 - 0.19 11.9 5.3 2.1 8.5 3.0 2.5 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region Laminin_II PF06009.7 ETO18470.1 - 0.25 11.1 7.6 0.79 9.4 5.2 1.9 1 1 0 1 1 1 0 Laminin Domain II COG2 PF06148.6 ETO18470.1 - 0.59 10.0 8.1 1.1 9.0 4.5 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2052 PF09747.4 ETO18470.1 - 0.97 9.3 8.3 1.7 8.5 5.8 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Mu-like_Pro PF10123.4 ETO18470.1 - 1.4 8.2 11.6 2.1 7.6 8.0 1.2 1 0 0 1 1 1 0 Mu-like prophage I protein IncA PF04156.9 ETO18470.1 - 1.7 8.1 11.8 2.9 7.4 8.2 1.4 1 0 0 1 1 1 0 IncA protein DUF4226 PF10774.4 ETO18470.1 - 2.3 8.3 7.4 14 5.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) Seryl_tRNA_N PF02403.17 ETO18470.1 - 2.7 8.0 14.7 49 3.9 10.3 2.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF972 PF06156.8 ETO18470.1 - 8.6 6.7 10.7 19 5.6 7.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Dynein_heavy PF03028.10 ETO18471.1 - 1.1e-188 628.5 0.2 1.1e-127 426.9 0.5 2.8 2 1 0 2 2 2 2 Dynein heavy chain and region D6 of dynein motor AAA_9 PF12781.2 ETO18471.1 - 1.2e-37 128.9 3.7 2.5e-37 127.9 2.0 2.0 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 MT PF12777.2 ETO18471.1 - 1.9e-12 46.6 0.2 3.3e-12 45.8 0.1 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Daxx PF03344.10 ETO18472.1 - 0.032 12.7 15.6 0.042 12.3 10.8 1.1 1 0 0 1 1 1 0 Daxx Family SAPS PF04499.10 ETO18472.1 - 0.13 10.8 9.6 0.17 10.4 6.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Macoilin PF09726.4 ETO18472.1 - 0.33 9.2 12.6 0.35 9.1 8.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Nop25 PF09805.4 ETO18472.1 - 0.62 10.1 19.9 1.1 9.3 13.8 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) CDC45 PF02724.9 ETO18472.1 - 0.85 7.5 11.5 1 7.3 8.0 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.7 ETO18472.1 - 5.9 5.5 9.8 8.1 5.0 6.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TraV PF09676.5 ETO18472.1 - 9.7 6.9 16.7 2.5e+03 -0.9 11.6 2.2 1 1 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) Sybindin PF04099.7 ETO18473.1 - 2.9e-21 75.6 1.6 4.3e-21 75.1 1.1 1.3 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 ETO18473.1 - 3.3e-05 23.7 0.8 9.1e-05 22.3 0.5 1.8 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region DUF2937 PF11157.3 ETO18473.1 - 0.062 12.6 0.0 0.098 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) WD40 PF00400.27 ETO18474.1 - 4.1e-23 80.3 7.4 1.7e-07 30.8 0.1 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat Ribosomal_S3Ae PF01015.13 ETO18475.1 - 1.3e-31 109.4 2.6 2.4e-30 105.3 1.8 2.0 1 1 0 1 1 1 1 Ribosomal S3Ae family GCM PF03615.10 ETO18475.1 - 0.27 10.8 3.4 0.13 11.8 0.4 1.9 2 0 0 2 2 2 0 GCM motif protein FUSC_2 PF13515.1 ETO18477.1 - 0.046 13.6 1.1 0.66 9.8 0.0 2.3 2 0 0 2 2 2 0 Fusaric acid resistance protein-like Mito_fiss_reg PF05308.6 ETO18478.1 - 0.068 12.5 6.6 0.12 11.6 4.6 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF4179 PF13786.1 ETO18478.1 - 0.41 10.9 2.6 0.61 10.3 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) CAP_N PF01213.14 ETO18478.1 - 1.1 8.4 11.2 1.8 7.7 7.7 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF4282 PF14110.1 ETO18478.1 - 4.9 7.4 11.4 0.54 10.4 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4282) OB_NTP_bind PF07717.11 ETO18479.1 - 2.3e-20 72.5 0.0 3.8e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold GlnE PF03710.10 ETO18479.1 - 0.095 11.9 0.3 0.12 11.5 0.2 1.1 1 0 0 1 1 1 0 Glutamate-ammonia ligase adenylyltransferase GST_N_3 PF13417.1 ETO18480.1 - 4.3e-14 52.4 0.1 7.4e-10 38.9 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETO18480.1 - 7.2e-08 32.3 0.0 0.00014 21.8 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 ETO18480.1 - 0.011 15.7 0.0 0.073 13.0 0.0 2.2 2 0 0 2 2 2 0 Glutaredoxin GST_N PF02798.15 ETO18480.1 - 0.019 15.1 0.0 0.044 13.9 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain TilS_C PF11734.3 ETO18480.1 - 0.13 11.4 0.2 3.2 7.0 0.0 2.7 2 1 1 3 3 3 0 TilS substrate C-terminal domain DNA_pol3_delta2 PF13177.1 ETO18481.1 - 0.013 15.1 1.1 0.56 9.8 0.2 2.2 1 1 1 2 2 2 0 DNA polymerase III, delta subunit DUF4002 PF13164.1 ETO18482.1 - 5.9e-05 22.9 17.5 5.9e-05 22.9 12.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4002) Guanylate_cyc PF00211.15 ETO18483.1 - 3.5e-09 36.2 0.1 4.6e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain RIH_assoc PF08454.6 ETO18483.1 - 0.056 13.0 3.2 0.074 12.6 2.2 1.3 1 1 0 1 1 1 0 RyR and IP3R Homology associated CDC45 PF02724.9 ETO18484.1 - 0.71 7.8 8.4 0.9 7.4 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DARPP-32 PF05395.7 ETO18484.1 - 1.7 8.7 7.3 0.65 10.1 3.3 1.6 2 0 0 2 2 2 0 Protein phosphatase inhibitor 1/DARPP-32 PrsW-protease PF13367.1 ETO18485.1 - 4.5e-09 35.7 11.6 9.4e-09 34.7 8.0 1.7 1 1 0 1 1 1 1 Protease prsW family Mucin PF01456.12 ETO18485.1 - 0.075 12.8 11.6 0.15 11.8 8.1 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein PDZ PF00595.19 ETO18486.1 - 0.0027 17.8 0.2 0.0079 16.3 0.2 1.8 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) WD40 PF00400.27 ETO18488.1 - 2.8e-35 118.9 4.8 1.3e-10 40.7 0.0 4.0 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO18488.1 - 4.2e-05 21.8 0.3 0.077 11.1 0.0 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO18488.1 - 0.00083 18.2 2.3 0.51 9.0 0.2 2.8 1 1 1 3 3 3 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO18488.1 - 0.0018 16.6 0.6 0.12 10.6 0.1 2.0 1 1 1 2 2 2 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO18488.1 - 0.021 14.2 0.3 0.21 10.9 0.1 1.9 1 1 1 2 2 2 0 PQQ-like domain DUF1258 PF06869.7 ETO18488.1 - 0.044 12.8 0.3 2.6 7.0 0.0 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1258) Hira PF07569.6 ETO18488.1 - 0.084 12.0 1.7 0.27 10.4 0.0 2.6 3 2 1 4 4 4 0 TUP1-like enhancer of split WD40 PF00400.27 ETO18489.1 - 3.2e-58 191.6 27.8 4e-11 42.3 0.3 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO18489.1 - 1.7e-08 33.0 9.4 0.00011 20.4 0.5 4.7 2 1 2 5 5 5 4 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO18489.1 - 0.0011 19.2 3.3 0.0011 19.2 2.3 3.0 2 0 0 2 2 2 1 TRAF-type zinc finger TPR_12 PF13424.1 ETO18490.1 - 9.7e-192 621.4 34.6 3e-28 97.5 0.1 7.6 1 1 8 10 10 10 10 Tetratricopeptide repeat TPR_10 PF13374.1 ETO18490.1 - 3.1e-89 290.6 0.0 8.7e-10 38.2 0.0 10.1 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_11 PF13414.1 ETO18490.1 - 5.1e-74 243.8 48.1 1.6e-16 59.7 1.7 6.6 4 2 3 7 7 7 7 TPR repeat TPR_7 PF13176.1 ETO18490.1 - 1.3e-73 237.0 15.5 6e-08 31.9 0.0 10.3 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_1 PF00515.23 ETO18490.1 - 3.6e-70 228.9 64.2 2e-10 39.8 0.8 11.2 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 ETO18490.1 - 4.1e-59 191.7 39.4 1.2e-07 31.1 0.2 10.9 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_8 PF13181.1 ETO18490.1 - 3.8e-50 163.9 72.6 2.7e-08 33.0 1.3 10.4 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_17 PF13431.1 ETO18490.1 - 3.5e-47 154.7 17.2 0.00034 20.5 0.0 10.9 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_16 PF13432.1 ETO18490.1 - 8.1e-30 102.8 0.1 1.5e-05 25.4 0.0 8.1 1 1 8 10 10 10 8 Tetratricopeptide repeat TPR_14 PF13428.1 ETO18490.1 - 8e-21 72.6 0.0 0.19 12.4 0.0 9.5 6 2 3 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO18490.1 - 2.4e-19 68.3 16.7 0.4 11.2 0.0 10.4 10 0 0 10 10 10 5 Tetratricopeptide repeat Apc3 PF12895.2 ETO18490.1 - 8.5e-16 57.8 28.6 0.00022 21.3 1.0 6.4 1 1 6 8 8 8 8 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 ETO18490.1 - 1.2e-13 50.7 46.1 0.024 14.5 0.5 9.3 8 1 1 9 9 9 6 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 ETO18490.1 - 3.5e-13 49.0 51.6 0.0001 22.0 1.7 10.5 10 0 0 10 10 10 5 Tetratricopeptide repeat SNAP PF14938.1 ETO18490.1 - 3.4e-12 46.1 19.0 0.00097 18.3 2.9 6.0 2 1 4 6 6 6 4 Soluble NSF attachment protein, SNAP TPR_19 PF14559.1 ETO18490.1 - 3.8e-11 43.1 10.8 0.021 15.1 0.1 7.0 2 1 8 10 10 10 4 Tetratricopeptide repeat PPR PF01535.15 ETO18490.1 - 8.9e-09 34.7 27.7 0.16 12.0 0.1 9.4 11 0 0 11 11 10 4 PPR repeat Musclin PF11037.3 ETO18490.1 - 1.7e-06 27.7 0.1 29 4.2 0.0 6.8 7 0 0 7 7 7 0 Insulin-resistance promoting peptide in skeletal muscle DUF627 PF04781.7 ETO18490.1 - 6.8e-06 25.6 11.4 0.24 11.0 0.1 7.0 3 2 4 7 7 7 1 Protein of unknown function (DUF627) Rab5-bind PF09311.6 ETO18490.1 - 0.0033 17.3 0.0 23 4.8 0.0 4.1 3 2 2 5 5 5 0 Rabaptin-like protein Syntaxin_2 PF14523.1 ETO18490.1 - 0.0066 16.4 0.0 35 4.4 0.0 4.8 4 2 0 4 4 4 0 Syntaxin-like protein RPN7 PF10602.4 ETO18490.1 - 0.0096 15.3 25.5 0.94 8.8 0.3 7.4 1 1 4 6 6 6 2 26S proteasome subunit RPN7 SHNi-TPR PF10516.4 ETO18490.1 - 0.0098 15.1 0.1 42 3.5 0.0 5.6 7 0 0 7 7 7 0 SHNi-TPR Sel1 PF08238.7 ETO18490.1 - 0.037 14.6 33.8 7.2 7.4 0.1 10.2 11 0 0 11 11 10 0 Sel1 repeat FATC PF02260.15 ETO18490.1 - 0.063 12.7 14.8 55 3.3 0.3 7.0 7 0 0 7 7 7 0 FATC domain Flu_NS2 PF00601.14 ETO18490.1 - 0.1 12.8 1.1 34 4.7 0.0 4.0 5 0 0 5 5 3 0 Influenza non-structural protein (NS2) PPR_2 PF13041.1 ETO18490.1 - 0.11 12.5 18.7 4.7 7.2 0.0 7.0 9 0 0 9 9 6 0 PPR repeat family TPR_21 PF09976.4 ETO18490.1 - 0.13 12.1 7.6 21 5.0 0.0 4.9 3 2 1 4 4 4 0 Tetratricopeptide repeat DLD PF14878.1 ETO18490.1 - 2.7 8.1 9.6 32 4.6 0.1 5.1 5 0 0 5 5 5 0 Death-like domain of SPT6 cNMP_binding PF00027.24 ETO18492.1 - 8.9e-15 54.2 0.0 9.5e-13 47.7 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain PLD_C PF12357.3 ETO18492.1 - 0.0018 17.7 0.0 0.0034 16.8 0.0 1.4 1 0 0 1 1 1 1 Phospholipase D C terminal DUF919 PF06034.6 ETO18492.1 - 0.14 11.7 0.5 0.96 9.1 0.0 2.5 3 1 1 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DUF4011 PF13195.1 ETO18494.1 - 1.6e-39 135.7 0.3 1.6e-39 135.7 0.2 2.3 3 0 0 3 3 2 1 Protein of unknown function (DUF4011) AAA_19 PF13245.1 ETO18494.1 - 1.1e-12 47.4 0.1 2.6e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 ETO18494.1 - 3.6e-08 33.2 0.1 9.5e-08 31.8 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 ETO18494.1 - 1.5e-06 27.9 0.0 2.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.16 ETO18494.1 - 2.6e-06 26.9 1.3 2.6e-06 26.9 0.9 2.6 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_10 PF12846.2 ETO18494.1 - 0.00033 20.1 0.0 0.0008 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA-like domain DUF2075 PF09848.4 ETO18494.1 - 0.00047 19.2 0.1 0.0011 18.0 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 ETO18494.1 - 0.0024 17.3 0.0 0.0055 16.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein ResIII PF04851.10 ETO18494.1 - 0.004 17.0 0.2 0.014 15.2 0.2 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 ETO18494.1 - 0.0052 16.2 0.0 0.018 14.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETO18494.1 - 0.0064 16.7 1.7 0.028 14.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain Adeno_IVa2 PF02456.10 ETO18494.1 - 0.018 13.7 0.2 0.068 11.8 0.0 1.8 2 1 0 2 2 2 0 Adenovirus IVa2 protein FtsK_SpoIIIE PF01580.13 ETO18494.1 - 0.018 14.5 0.1 0.06 12.8 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family DEAD PF00270.24 ETO18494.1 - 0.023 14.1 0.0 0.05 13.1 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase Helicase_RecD PF05127.9 ETO18494.1 - 0.032 13.8 0.0 0.079 12.5 0.0 1.7 1 0 0 1 1 1 0 Helicase TrwB_AAD_bind PF10412.4 ETO18494.1 - 0.035 12.7 0.0 0.09 11.3 0.0 1.6 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.1 ETO18494.1 - 0.045 13.8 0.0 0.26 11.4 0.0 2.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 ETO18494.1 - 0.045 13.9 0.0 0.21 11.7 0.0 2.2 1 1 0 1 1 1 0 RNA helicase KaiC PF06745.8 ETO18494.1 - 0.057 12.5 0.0 0.2 10.7 0.0 1.9 1 0 0 1 1 1 0 KaiC AAA_17 PF13207.1 ETO18494.1 - 0.13 13.0 2.8 0.98 10.2 0.2 3.6 3 1 0 3 3 2 0 AAA domain ArgK PF03308.11 ETO18494.1 - 0.16 10.7 0.1 0.3 9.8 0.0 1.4 1 0 0 1 1 1 0 ArgK protein TraT PF05818.7 ETO18495.1 - 3.8e-56 189.9 2.5 4.5e-56 189.6 1.8 1.1 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein PAT1 PF09770.4 ETO18496.1 - 3.1e-07 29.0 39.9 2.1e-05 23.0 26.5 2.3 1 1 1 2 2 2 2 Topoisomerase II-associated protein PAT1 CagX PF03524.10 ETO18496.1 - 0.0073 15.5 1.3 0.013 14.7 0.9 1.4 1 0 0 1 1 1 1 Conjugal transfer protein Neur_chan_memb PF02932.11 ETO18496.1 - 0.091 12.6 9.5 0.11 12.4 6.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2946 PF11162.3 ETO18496.1 - 0.11 12.7 6.5 0.19 11.9 4.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) PXA PF02194.10 ETO18496.1 - 0.41 10.1 4.1 0.67 9.4 2.8 1.3 1 0 0 1 1 1 0 PXA domain DUF605 PF04652.11 ETO18496.1 - 0.99 8.7 14.5 1.2 8.4 10.1 1.1 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 ETO18496.1 - 1.2 9.0 22.8 1.3 8.7 15.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.1 ETO18496.1 - 2 7.3 4.8 2.3 7.0 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NicO PF03824.11 ETO18496.1 - 4.1 6.6 7.6 5.3 6.2 5.3 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein DUF3602 PF12223.3 ETO18496.1 - 5.6 7.4 13.4 17 5.9 9.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3602) Hid1 PF12722.2 ETO18496.1 - 6.5 4.2 14.5 8.5 3.9 10.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAM_1 PF00536.25 ETO18497.1 - 2.7e-07 30.6 0.1 4.5e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO18497.1 - 6.3e-07 29.1 0.0 1.7e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) B56 PF01603.15 ETO18498.1 - 4.8e-44 150.6 2.2 1.2e-42 145.9 1.6 2.0 1 1 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Syntaphilin PF15290.1 ETO18499.1 - 0.081 12.4 1.7 0.14 11.5 1.2 1.3 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp SR-25 PF10500.4 ETO18499.1 - 0.37 10.2 5.4 0.7 9.3 3.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2743 PF10899.3 ETO18500.1 - 0.29 10.4 8.3 0.5 9.7 5.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2743) Gag_spuma PF03276.9 ETO18501.1 - 2.1 6.5 11.8 3 6.0 8.2 1.1 1 0 0 1 1 1 0 Spumavirus gag protein MIP-T3 PF10243.4 ETO18502.1 - 0.00078 18.0 10.1 0.00078 18.0 7.0 1.9 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 DUF106 PF01956.11 ETO18502.1 - 0.029 13.9 1.1 0.059 12.9 0.7 1.5 1 0 0 1 1 1 0 Integral membrane protein DUF106 CobT PF06213.7 ETO18502.1 - 0.031 13.4 12.5 0.024 13.7 0.5 2.3 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Nucleoplasmin PF03066.10 ETO18502.1 - 1.1 8.7 17.3 0.024 14.1 0.8 2.5 2 0 0 2 2 2 0 Nucleoplasmin Peroxin-13_N PF04088.8 ETO18502.1 - 5.1 7.0 7.0 1.8 8.4 1.3 2.7 2 1 1 3 3 3 0 Peroxin 13, N-terminal region Rota_NS35 PF02509.9 ETO18503.1 - 0.082 11.6 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 Rotavirus non-structural protein 35 Mating_N PF12731.2 ETO18504.1 - 0.085 12.7 4.6 0.16 11.8 0.2 3.1 1 1 1 3 3 3 0 Mating-type protein beta 1 V-SNARE PF05008.10 ETO18504.1 - 1.1 9.4 21.2 0.69 10.1 6.1 3.1 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Baculo_PEP_C PF04513.7 ETO18504.1 - 1.6 8.5 13.1 2 8.2 2.8 2.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF342 PF03961.8 ETO18504.1 - 1.8 6.9 22.3 0.35 9.2 3.9 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF342) SRP72 PF08492.7 ETO18505.1 - 0.074 13.4 3.3 0.25 11.7 1.2 2.4 2 0 0 2 2 2 0 SRP72 RNA-binding domain DEP PF00610.16 ETO18506.1 - 1.5e-12 47.0 0.1 3.7e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) EF-hand_6 PF13405.1 ETO18506.1 - 7.2e-06 25.4 0.1 0.11 12.3 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 ETO18506.1 - 3.5e-05 23.8 0.3 7.9e-05 22.7 0.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO18506.1 - 4.2e-05 22.5 0.9 0.11 11.8 0.1 2.5 2 0 0 2 2 2 2 EF hand W2 PF02020.13 ETO18506.1 - 0.27 11.1 2.2 11 6.0 0.0 2.6 2 1 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon OppC_N PF12911.2 ETO18507.1 - 0.21 10.9 0.0 0.21 10.9 0.0 3.5 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C WD40 PF00400.27 ETO18508.1 - 6.1e-07 29.0 0.2 4.1e-05 23.3 0.2 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat Laminin_G_3 PF13385.1 ETO18509.1 - 5.9e-05 23.3 0.0 0.00011 22.5 0.0 1.4 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily BCIP PF13862.1 ETO18510.1 - 2.3e-19 69.6 6.7 5e-19 68.5 4.7 1.6 1 1 0 1 1 1 1 p21-C-terminal region-binding protein O-antigen_lig PF13425.1 ETO18510.1 - 0.019 14.9 0.2 0.019 14.9 0.1 1.8 2 0 0 2 2 2 0 O-antigen ligase like membrane protein Cytochrom_C_asm PF01578.15 ETO18510.1 - 0.026 14.0 0.1 0.026 14.0 0.1 1.5 2 0 0 2 2 2 0 Cytochrome C assembly protein CCSMST1 PF15013.1 ETO18510.1 - 0.044 13.7 0.1 0.14 12.0 0.1 1.9 1 0 0 1 1 1 0 CCSMST1 family 7TMR-DISM_7TM PF07695.6 ETO18510.1 - 5.5 6.6 22.8 0.42 10.2 5.8 2.2 2 0 0 2 2 2 0 7TM diverse intracellular signalling DEAD PF00270.24 ETO18511.1 - 5.6e-22 78.0 0.0 1.2e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 ETO18511.1 - 0.0015 17.4 0.0 0.0025 16.7 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 ETO18511.1 - 0.077 12.7 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain GTP_EFTU PF00009.22 ETO18511.1 - 0.084 12.2 0.2 0.25 10.7 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MobB PF03205.9 ETO18511.1 - 0.098 12.3 0.0 0.28 10.8 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NOT2_3_5 PF04153.13 ETO18512.1 - 3.4e-24 85.2 21.3 3.5e-20 72.2 3.0 3.9 4 0 0 4 4 4 2 NOT2 / NOT3 / NOT5 family SWIRM PF04433.12 ETO18512.1 - 0.072 13.2 0.8 5.8 7.1 0.1 2.7 2 0 0 2 2 2 0 SWIRM domain DUF2417 PF10329.4 ETO18513.1 - 0.00047 19.6 0.3 0.00065 19.1 0.2 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Pkinase PF00069.20 ETO18516.1 - 1.2e-24 86.8 0.0 1.3e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO18516.1 - 2.8e-06 26.5 0.0 3.5e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETO18516.1 - 0.00024 20.9 0.0 0.00032 20.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 ETO18516.1 - 0.033 13.7 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.20 ETO18517.1 - 8.7e-15 54.5 0.0 1.5e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO18517.1 - 3.9e-06 26.1 0.0 5.9e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LMBR1 PF04791.11 ETO18519.1 - 0.026 13.1 1.6 0.034 12.7 1.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein MIP-T3 PF10243.4 ETO18519.1 - 0.033 12.6 54.5 0.037 12.5 37.8 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DEAD PF00270.24 ETO18520.1 - 3.8e-07 29.7 0.0 8.3e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 ETO18520.1 - 0.036 13.9 0.0 0.036 13.9 0.0 2.6 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF1034 PF06280.7 ETO18520.1 - 2.5 8.5 6.2 0.42 11.0 1.1 2.0 2 0 0 2 2 2 0 Fn3-like domain (DUF1034) HATPase_c_2 PF13581.1 ETO18521.1 - 7.9e-08 32.1 0.0 1.5e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.21 ETO18521.1 - 2.3e-06 27.3 0.0 4.6e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HTH_IclR PF09339.5 ETO18521.1 - 6.9e-05 22.3 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain GntR PF00392.16 ETO18521.1 - 0.00016 21.0 0.0 0.00031 20.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family TrmB PF01978.14 ETO18521.1 - 0.00022 20.8 0.0 0.00056 19.5 0.0 1.7 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.1 ETO18521.1 - 0.002 17.9 0.0 0.0045 16.7 0.0 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR PF01047.17 ETO18521.1 - 0.0029 17.2 0.0 0.0065 16.1 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.1 ETO18521.1 - 0.0046 16.3 0.0 0.093 12.1 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_DeoR PF08220.7 ETO18521.1 - 0.0087 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HATPase_c_3 PF13589.1 ETO18521.1 - 0.015 14.9 0.1 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MarR_2 PF12802.2 ETO18521.1 - 0.016 14.8 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.15 ETO18521.1 - 0.035 14.2 0.0 0.071 13.2 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator Ank_2 PF12796.2 ETO18522.1 - 5.3e-14 52.3 0.2 7.4e-07 29.4 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETO18522.1 - 1.9e-10 39.9 0.0 0.0043 16.7 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 ETO18522.1 - 1.9e-06 27.5 0.0 0.49 10.7 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 ETO18522.1 - 4.8e-06 26.9 0.1 0.51 10.9 0.0 4.3 2 2 2 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO18522.1 - 0.0061 16.7 0.2 11 6.3 0.0 3.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Med6 PF04934.9 ETO18523.1 - 1.9e-21 76.0 0.5 4.6e-21 74.8 0.3 1.7 1 0 0 1 1 1 1 MED6 mediator sub complex component PBP1_TM PF14812.1 ETO18525.1 - 6.2 7.1 10.0 12 6.3 6.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Carboxyl_trans PF01039.17 ETO18526.1 - 0.71 8.1 2.5 1.1 7.5 1.7 1.2 1 0 0 1 1 1 0 Carboxyl transferase domain DUF4207 PF13904.1 ETO18526.1 - 1.4 8.2 17.2 2.8 7.2 11.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Ion_trans PF00520.26 ETO18528.1 - 7.1e-12 45.0 15.5 1.1e-06 28.0 5.1 2.2 2 0 0 2 2 2 2 Ion transport protein Baculo_11_kDa PF06143.6 ETO18528.1 - 1.9 7.8 6.7 3.5 7.0 0.5 2.8 2 0 0 2 2 2 0 Baculovirus 11 kDa family Tetraspannin PF00335.15 ETO18529.1 - 0.33 10.2 10.1 0.27 10.4 5.6 1.8 2 0 0 2 2 2 0 Tetraspanin family Ion_trans PF00520.26 ETO18529.1 - 2.1 7.5 9.8 0.48 9.6 3.3 2.4 3 1 0 3 3 3 0 Ion transport protein YhdB PF14148.1 ETO18530.1 - 0.29 10.9 3.2 1.2 8.9 1.4 2.7 1 1 2 3 3 3 0 YhdB-like protein DUF904 PF06005.7 ETO18531.1 - 0.018 15.3 13.0 0.018 15.3 9.0 5.3 2 2 3 5 5 5 0 Protein of unknown function (DUF904) HALZ PF02183.13 ETO18531.1 - 0.062 13.0 0.0 0.062 13.0 0.0 6.1 5 2 0 6 6 6 0 Homeobox associated leucine zipper DUF948 PF06103.6 ETO18531.1 - 0.4 10.5 27.1 0.067 13.0 3.5 4.3 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF869 PF05911.6 ETO18531.1 - 0.65 8.1 46.6 0.24 9.6 25.3 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) DUF972 PF06156.8 ETO18531.1 - 2.7 8.4 49.7 0.16 12.2 2.2 4.7 1 1 2 4 4 4 0 Protein of unknown function (DUF972) DivIVA PF05103.8 ETO18531.1 - 4.8 7.2 49.3 2.7 8.0 11.4 4.2 1 1 3 4 4 4 0 DivIVA protein Kinesin-related PF06548.6 ETO18531.1 - 9.3 4.6 43.4 1.8 6.9 26.8 1.8 1 1 1 2 2 2 0 Kinesin-related Striatin PF08232.7 ETO18532.1 - 0.16 12.3 7.0 0.1 12.9 3.6 1.6 1 1 1 2 2 2 0 Striatin family DUF2146 PF10220.4 ETO18532.1 - 1 7.2 9.7 1.2 7.0 6.7 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) RNase_H2-Ydr279 PF09468.5 ETO18532.1 - 1.2 8.2 11.6 0.67 9.0 6.7 1.5 1 1 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) AAA PF00004.24 ETO18534.1 - 2.7e-05 24.3 0.0 0.00012 22.2 0.0 2.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETO18534.1 - 0.00041 20.4 0.8 0.0072 16.4 0.0 3.5 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.9 ETO18534.1 - 0.00042 20.0 0.0 0.0057 16.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 ETO18534.1 - 0.0065 16.7 3.1 0.012 15.9 0.0 3.0 2 1 0 2 2 2 1 ABC transporter Sigma54_activ_2 PF14532.1 ETO18534.1 - 0.0069 16.4 0.1 0.1 12.6 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain Miro PF08477.8 ETO18534.1 - 0.019 15.4 2.4 0.17 12.4 0.0 3.7 4 0 0 4 4 4 0 Miro-like protein AAA_16 PF13191.1 ETO18534.1 - 0.12 12.3 0.0 1.1 9.2 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain Rsbr_N PF08678.5 ETO18536.1 - 0.027 14.3 2.9 0.055 13.3 0.5 2.6 3 1 0 3 3 3 0 Rsbr N terminal DUF2339 PF10101.4 ETO18537.1 - 0.0016 16.8 0.4 0.0021 16.4 0.3 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) SR-25 PF10500.4 ETO18537.1 - 0.41 10.0 16.5 0.94 8.8 11.4 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3633 PF12315.3 ETO18537.1 - 3.5 6.8 5.0 7.3 5.8 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3633) LIM PF00412.17 ETO18538.1 - 0.5 10.4 5.3 1.4 9.0 3.7 1.7 1 1 0 1 1 1 0 LIM domain DZR PF12773.2 ETO18539.1 - 0.0042 16.8 3.6 0.0096 15.7 2.5 1.6 1 0 0 1 1 1 1 Double zinc ribbon DUF4205 PF13898.1 ETO18539.1 - 0.0067 15.2 0.1 0.017 13.8 0.0 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4205) AAA_23 PF13476.1 ETO18539.1 - 0.0073 16.6 2.3 0.0091 16.3 1.6 1.2 1 0 0 1 1 1 1 AAA domain zf-UBR PF02207.15 ETO18539.1 - 0.029 14.0 0.6 0.063 12.9 0.4 1.6 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) zf-ribbon_3 PF13248.1 ETO18539.1 - 0.033 13.3 4.4 0.065 12.4 3.0 1.5 1 0 0 1 1 1 0 zinc-ribbon domain DUF2616 PF11077.3 ETO18539.1 - 0.054 12.9 5.7 0.12 11.8 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2616) zinc_ribbon_2 PF13240.1 ETO18539.1 - 0.075 12.5 7.6 0.15 11.5 5.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Mut7-C PF01927.11 ETO18539.1 - 0.1 12.5 0.7 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 Mut7-C RNAse domain Sulfatase PF00884.18 ETO18540.1 - 2.2e-29 102.6 0.0 2.6e-29 102.4 0.0 1.0 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 ETO18540.1 - 0.12 11.6 0.1 0.21 10.9 0.0 1.3 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase RhoGAP PF00620.22 ETO18541.1 - 0.00015 21.4 0.0 0.00029 20.4 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain AF1Q PF15017.1 ETO18541.1 - 1.6 8.7 7.1 3.1 7.7 4.9 1.4 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator BRI3BP PF14965.1 ETO18542.1 - 0.038 13.3 0.0 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 Negative regulator of p53/TP53 DUF342 PF03961.8 ETO18542.1 - 0.043 12.2 3.2 0.053 11.9 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 ETO18542.1 - 0.14 10.0 1.3 0.13 10.0 0.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATP-synt_B PF00430.13 ETO18542.1 - 0.25 11.1 11.2 0.5 10.1 7.8 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) WXG100 PF06013.7 ETO18542.1 - 0.49 10.4 5.3 0.86 9.6 3.7 1.4 1 0 0 1 1 1 0 Proteins of 100 residues with WXG DUF2408 PF10303.4 ETO18542.1 - 0.75 9.9 5.8 2.7 8.0 4.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Spc24 PF08286.6 ETO18542.1 - 2.6 7.7 8.2 3.1 7.5 4.7 1.8 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF4140 PF13600.1 ETO18542.1 - 3.6 8.0 8.7 0.44 11.0 0.9 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) GSHPx PF00255.14 ETO18543.1 - 4.7e-36 122.4 0.1 1e-35 121.3 0.0 1.6 2 0 0 2 2 2 1 Glutathione peroxidase Redoxin PF08534.5 ETO18543.1 - 0.00054 19.5 0.0 0.00084 18.8 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 ETO18543.1 - 0.0026 17.4 0.1 0.0058 16.3 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family NKWYS PF10364.4 ETO18543.1 - 0.11 12.2 0.6 0.2 11.3 0.4 1.5 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein Cyclin_C PF02984.14 ETO18544.1 - 0.0013 18.6 0.1 0.0044 16.9 0.0 1.9 1 0 0 1 1 1 1 Cyclin, C-terminal domain Daxx PF03344.10 ETO18545.1 - 0.00017 20.2 15.4 0.00025 19.6 10.7 1.4 1 0 0 1 1 1 1 Daxx Family RasGEF_N PF00618.15 ETO18545.1 - 0.0096 16.0 2.8 0.95 9.5 0.0 3.7 4 0 0 4 4 4 1 RasGEF N-terminal motif DUF1510 PF07423.6 ETO18545.1 - 0.79 9.0 27.5 0.048 13.0 15.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Vfa1 PF08432.5 ETO18545.1 - 2.8 7.9 23.4 0.091 12.7 11.2 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Pox_Ag35 PF03286.9 ETO18545.1 - 4.8 6.6 27.1 2.3 7.6 17.0 1.8 1 1 0 1 1 1 0 Pox virus Ag35 surface protein UQ_con PF00179.21 ETO18546.1 - 2.6e-10 39.8 0.6 3.2e-10 39.5 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 ETO18546.1 - 8.8e-05 22.3 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 RWD domain ClpB_D2-small PF10431.4 ETO18548.1 - 2.8e-07 30.3 0.4 5.4e-07 29.4 0.3 1.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Asp_protease PF09668.5 ETO18549.1 - 1.3e-18 66.7 1.4 5e-14 51.9 0.1 2.3 1 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.1 ETO18549.1 - 9.7e-06 25.3 0.0 2.3e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 ETO18549.1 - 0.0058 17.0 0.0 0.024 15.1 0.0 2.0 1 1 1 2 2 2 1 Aspartyl protease RicinB_lectin_2 PF14200.1 ETO18550.1 - 1.9e-21 76.4 6.8 2e-13 50.6 0.6 2.6 1 1 2 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 ETO18550.1 - 4.4e-06 26.7 10.7 0.00044 20.2 1.8 1.8 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain FGF PF00167.13 ETO18550.1 - 0.0057 16.4 0.1 0.058 13.1 0.0 2.2 1 1 1 2 2 2 1 Fibroblast growth factor Agglutinin PF07468.6 ETO18550.1 - 0.093 12.7 2.5 0.081 12.9 0.8 1.6 2 0 0 2 2 2 0 Agglutinin Exo_endo_phos PF03372.18 ETO18551.1 - 5e-06 26.6 1.9 1.8e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family FSIP1 PF15554.1 ETO18551.1 - 0.099 11.4 27.7 0.13 11.0 19.2 1.1 1 0 0 1 1 1 0 FSIP1 family Ndc1_Nup PF09531.5 ETO18551.1 - 0.69 8.2 8.9 0.85 7.9 6.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MDM1 PF15501.1 ETO18551.1 - 7 5.4 30.8 9.5 5.0 21.4 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 ATP-synt_E_2 PF08112.6 ETO18552.1 - 0.21 11.6 1.7 1.6 8.8 0.2 2.4 3 0 0 3 3 3 0 ATP synthase epsilon subunit DUF3974 PF13120.1 ETO18554.1 - 0.068 12.9 0.8 0.15 11.8 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) Striatin PF08232.7 ETO18554.1 - 0.38 11.0 7.9 0.091 13.0 1.4 2.1 2 0 0 2 2 2 0 Striatin family Phosphoesterase PF04185.9 ETO18555.1 - 4.2e-25 88.7 1.8 4.9e-25 88.5 1.2 1.0 1 0 0 1 1 1 1 Phosphoesterase family TFCD_C PF12612.3 ETO18556.1 - 0.0056 16.1 0.0 0.02 14.3 0.0 1.9 1 1 0 1 1 1 1 Tubulin folding cofactor D C terminal Birna_VP4 PF01768.11 ETO18556.1 - 0.034 13.1 0.0 0.046 12.7 0.0 1.1 1 0 0 1 1 1 0 Birnavirus VP4 protein Arm PF00514.18 ETO18556.1 - 1.4 8.8 4.4 1.9 8.4 0.0 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Flexi_CP PF00286.15 ETO18557.1 - 0.017 14.8 0.3 0.033 13.8 0.2 1.5 1 0 0 1 1 1 0 Viral coat protein HLH PF00010.21 ETO18558.1 - 0.0013 18.3 1.1 0.0035 16.9 0.8 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain VWA_2 PF13519.1 ETO18559.1 - 2.8e-05 24.2 0.0 3.4e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 ETO18559.1 - 0.02 14.0 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein DUF832 PF05734.6 ETO18559.1 - 0.035 13.3 0.3 0.053 12.7 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) IQ PF00612.22 ETO18560.1 - 0.62 9.8 5.4 43 4.1 0.0 4.5 4 0 0 4 4 4 0 IQ calmodulin-binding motif DENN PF02141.16 ETO18561.1 - 2.2e-32 112.2 2.2 2.2e-32 112.2 1.5 1.5 2 0 0 2 2 2 1 DENN (AEX-3) domain dDENN PF03455.14 ETO18561.1 - 4.3e-14 52.3 7.9 7.7e-14 51.5 5.5 1.4 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.13 ETO18562.1 - 4.6e-10 39.3 0.0 9.4e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 uDENN domain SRP54 PF00448.17 ETO18562.1 - 0.017 14.6 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ArfGap PF01412.13 ETO18563.1 - 2.5e-23 82.0 1.4 3.5e-23 81.6 1.0 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-B_box PF00643.19 ETO18563.1 - 2.6 8.0 9.3 7.8 6.4 6.4 1.8 1 1 0 1 1 1 0 B-box zinc finger HEAT PF02985.17 ETO18564.1 - 1.8e-08 33.7 1.7 0.59 10.3 0.0 4.7 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.1 ETO18564.1 - 2.5e-08 34.1 1.6 0.0031 17.9 0.2 3.7 3 1 1 4 4 4 3 HEAT-like repeat HEAT_2 PF13646.1 ETO18564.1 - 1.6e-06 28.3 4.9 0.022 15.0 0.2 3.6 3 1 1 4 4 4 3 HEAT repeats Cnd1 PF12717.2 ETO18564.1 - 5.1e-06 26.4 5.2 0.042 13.6 0.0 3.8 2 2 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 ETO18564.1 - 0.00081 19.7 0.2 0.091 13.1 0.0 2.9 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region UME PF08064.8 ETO18564.1 - 0.015 15.2 0.1 0.084 12.8 0.0 2.3 2 0 0 2 2 2 0 UME (NUC010) domain Xpo1 PF08389.7 ETO18564.1 - 0.06 13.2 0.8 0.19 11.6 0.0 2.3 3 2 0 3 3 3 0 Exportin 1-like protein DUF2435 PF10363.4 ETO18564.1 - 0.06 13.2 0.3 0.38 10.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) TMF_DNA_bd PF12329.3 ETO18565.1 - 0.0046 16.7 7.3 0.0046 16.7 5.1 1.6 1 1 0 1 1 1 1 TATA element modulatory factor 1 DNA binding Transposase_22 PF02994.9 ETO18565.1 - 0.021 13.3 2.9 0.023 13.1 2.0 1.0 1 0 0 1 1 1 0 L1 transposable element K-box PF01486.12 ETO18565.1 - 0.028 14.1 11.4 0.063 13.0 7.9 1.6 1 1 0 1 1 1 0 K-box region TBPIP PF07106.8 ETO18565.1 - 0.033 13.7 7.2 0.043 13.3 5.0 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) AAA_27 PF13514.1 ETO18565.1 - 0.036 11.7 4.7 0.044 11.4 3.3 1.0 1 0 0 1 1 1 0 AAA domain DUF342 PF03961.8 ETO18565.1 - 0.055 11.8 3.3 0.062 11.7 2.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Cut12 PF11500.3 ETO18565.1 - 0.42 10.3 5.0 0.59 9.8 3.4 1.2 1 0 0 1 1 1 0 Spindle pole body formation-associated protein DUF874 PF05917.6 ETO18565.1 - 0.43 9.3 5.7 0.37 9.6 2.3 1.6 1 1 1 2 2 2 0 Helicobacter pylori protein of unknown function (DUF874) YlqD PF11068.3 ETO18565.1 - 1.4 8.9 11.4 0.24 11.4 3.8 1.9 1 1 0 1 1 1 0 YlqD protein Muted PF14942.1 ETO18565.1 - 1.4 8.7 8.0 1.8 8.4 5.1 1.5 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein IncA PF04156.9 ETO18565.1 - 1.5 8.3 10.9 6.5 6.3 7.6 1.8 1 1 1 2 2 2 0 IncA protein ACCA PF03255.9 ETO18565.1 - 1.7 8.1 4.1 3 7.3 2.7 1.5 1 1 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Adeno_E3 PF06040.6 ETO18566.1 - 0.029 14.3 2.2 0.085 12.8 0.0 2.6 2 1 2 4 4 4 0 Adenovirus E3 protein DUF4200 PF13863.1 ETO18566.1 - 5.4 6.9 37.8 3.1 7.7 13.4 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DASH_Dam1 PF08653.5 ETO18566.1 - 5.4 6.8 11.9 7.9 6.3 1.4 3.9 3 1 0 3 3 3 0 DASH complex subunit Dam1 ADIP PF11559.3 ETO18566.1 - 5.9 6.7 35.9 0.042 13.7 7.4 2.8 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding PH_11 PF15413.1 ETO18567.1 - 0.0043 17.2 0.5 0.072 13.3 0.1 2.8 2 1 1 3 3 3 1 Pleckstrin homology domain PH PF00169.24 ETO18567.1 - 0.0046 17.1 2.0 0.21 11.7 0.3 3.2 3 1 0 3 3 3 1 PH domain PH_6 PF15406.1 ETO18567.1 - 0.018 15.1 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain PH_3 PF14593.1 ETO18567.1 - 0.023 14.5 0.0 0.061 13.2 0.0 1.7 1 0 0 1 1 1 0 PH domain KBP_C PF12309.3 ETO18568.1 - 1.7e-53 181.9 9.3 1.2e-39 136.3 3.0 2.2 2 0 0 2 2 2 2 KIF-1 binding protein C terminal DUF3387 PF11867.3 ETO18568.1 - 0.0032 16.4 1.6 0.0057 15.6 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3387) Ada3 PF10198.4 ETO18568.1 - 0.0033 17.1 2.1 0.008 15.9 1.5 1.7 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 Chitin_bind_4 PF00379.18 ETO18569.1 - 0.026 14.8 0.1 0.66 10.2 0.1 2.6 2 0 0 2 2 2 0 Insect cuticle protein SRP14 PF02290.10 ETO18569.1 - 0.046 13.6 0.2 0.046 13.6 0.1 2.5 3 0 0 3 3 3 0 Signal recognition particle 14kD protein Sigma70_ner PF04546.8 ETO18569.1 - 1.7 8.1 8.3 1 8.9 0.2 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region YejG PF13989.1 ETO18570.1 - 0.036 14.1 0.7 0.13 12.2 0.1 2.0 2 0 0 2 2 2 0 YejG-like protein Fib_alpha PF08702.5 ETO18571.1 - 0.00096 19.2 5.7 0.00096 19.2 3.9 4.4 2 1 2 5 5 5 1 Fibrinogen alpha/beta chain family eRF1_1 PF03463.10 ETO18571.1 - 0.011 15.3 0.6 0.028 13.9 0.2 1.7 1 1 0 1 1 1 0 eRF1 domain 1 Phi-29_GP16_7 PF06720.6 ETO18571.1 - 0.039 13.6 3.7 0.068 12.8 0.7 2.8 2 0 0 2 2 2 0 Bacteriophage phi-29 early protein GP16.7 ECM11 PF15463.1 ETO18571.1 - 2.5 8.3 12.8 0.14 12.4 3.5 3.1 2 1 0 2 2 2 0 Extracellular mutant protein 11 DUF4164 PF13747.1 ETO18571.1 - 4.4 7.5 15.2 2 8.6 1.2 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4164) NPV_P10 PF05531.7 ETO18571.1 - 9.3 6.5 13.2 5.9 7.2 0.3 4.7 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein RGS PF00615.14 ETO18572.1 - 0.0053 16.8 0.1 0.0082 16.2 0.1 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain MFS_1 PF07690.11 ETO18573.1 - 3.8e-10 39.0 0.0 5.8e-10 38.4 0.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 ETO18574.1 - 3.9e-07 29.1 7.0 5.6e-07 28.5 4.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETO18574.1 - 0.00064 18.4 8.2 0.077 11.5 1.2 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 ETO18574.1 - 0.0013 18.5 0.1 0.0013 18.5 0.1 2.5 3 1 1 4 4 4 1 MFS_1 like family Cation_efflux PF01545.16 ETO18575.1 - 1e-19 70.7 0.1 1.3e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Cation efflux family Arm PF00514.18 ETO18576.1 - 2.1e-05 24.1 0.0 1.8 8.5 0.0 3.5 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat CHU_C PF13585.1 ETO18576.1 - 0.056 13.3 0.1 2.2 8.2 0.0 2.4 2 0 0 2 2 2 0 C-terminal domain of CHU protein family FhuF_C PF11575.3 ETO18577.1 - 0.093 12.3 1.2 0.13 11.8 0.9 1.2 1 0 0 1 1 1 0 FhuF 2Fe-2S C-terminal domain DUF3402 PF11882.3 ETO18579.1 - 0.0034 16.5 0.2 0.0037 16.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) FPL PF09758.4 ETO18579.1 - 0.062 13.0 0.4 0.069 12.9 0.3 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein Hydantoinase_B PF02538.9 ETO18579.1 - 0.065 11.4 0.0 0.069 11.3 0.0 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase GP41 PF00517.12 ETO18579.1 - 0.08 12.4 1.9 0.098 12.2 1.3 1.2 1 0 0 1 1 1 0 Retroviral envelope protein Spore_GerAC PF05504.6 ETO18579.1 - 0.083 12.6 0.1 0.15 11.8 0.0 1.4 1 1 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Aha1_N PF09229.6 ETO18579.1 - 0.13 12.0 0.2 0.18 11.6 0.1 1.3 1 1 0 1 1 1 0 Activator of Hsp90 ATPase, N-terminal 7tm_1 PF00001.16 ETO18580.1 - 0.029 13.5 1.5 0.048 12.7 1.0 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF457 PF04307.9 ETO18580.1 - 0.082 12.2 0.0 0.095 12.0 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) DUF106 PF01956.11 ETO18580.1 - 9.5 5.7 9.3 1.4 8.4 3.4 1.8 1 1 1 2 2 2 0 Integral membrane protein DUF106 RabGAP-TBC PF00566.13 ETO18581.1 - 2.2e-16 60.0 8.0 2.2e-16 60.0 5.5 1.5 1 1 1 2 2 2 1 Rab-GTPase-TBC domain Ribosomal_S15 PF00312.17 ETO18581.1 - 0.59 9.9 4.8 5.7 6.7 3.3 2.0 2 0 0 2 2 2 0 Ribosomal protein S15 YjgP_YjgQ PF03739.9 ETO18582.1 - 0.0059 15.3 1.1 0.0077 15.0 0.8 1.1 1 0 0 1 1 1 1 Predicted permease YjgP/YjgQ family Ndc1_Nup PF09531.5 ETO18582.1 - 1.5 7.1 4.6 1.7 6.9 3.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Afaf PF15339.1 ETO18582.1 - 1.6 8.2 14.3 0.16 11.5 5.3 2.0 1 1 1 2 2 2 0 Acrosome formation-associated factor TMEM51 PF15345.1 ETO18582.1 - 6.3 6.4 11.1 8.3 6.0 7.5 1.4 1 1 0 1 1 1 0 Transmembrane protein 51 DUF2368 PF10166.4 ETO18583.1 - 0.18 11.4 2.1 0.4 10.3 1.4 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) Rep_Org_C PF06926.6 ETO18584.1 - 0.32 11.1 3.7 0.42 10.7 2.3 1.4 1 1 0 1 1 1 0 Putative replisome organiser protein C-terminus WD40 PF00400.27 ETO18585.1 - 1.4e-62 205.4 23.0 1.2e-11 44.0 0.2 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO18585.1 - 2.4e-16 59.0 2.2 0.0011 17.1 0.1 6.3 2 1 3 5 5 5 4 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO18585.1 - 2.1e-06 28.0 3.5 6.3e-06 26.4 2.4 1.9 1 0 0 1 1 1 1 TRAF-type zinc finger PQQ_2 PF13360.1 ETO18585.1 - 0.0018 17.7 0.6 0.12 11.7 0.0 2.7 3 0 0 3 3 3 1 PQQ-like domain DUF3601 PF12208.3 ETO18585.1 - 0.021 14.7 0.2 5.6 6.9 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF3601) zf-C3HC4_2 PF13923.1 ETO18585.1 - 0.92 9.5 6.3 0.18 11.8 0.7 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.13 ETO18586.1 - 2.8e-06 27.5 1.0 2.8e-06 27.5 0.7 2.6 2 0 0 2 2 2 1 TRAF-type zinc finger GTP_EFTU PF00009.22 ETO18586.1 - 0.052 12.9 0.8 0.093 12.1 0.5 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain zf-C3HC4_2 PF13923.1 ETO18586.1 - 0.2 11.7 1.8 2.2 8.3 1.3 2.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ODR4-like PF14778.1 ETO18586.1 - 0.32 9.6 5.8 0.1 11.2 1.7 1.7 1 1 1 2 2 2 0 Olfactory receptor 4-like Mito_fiss_reg PF05308.6 ETO18587.1 - 0.0082 15.5 1.8 0.0094 15.3 1.2 1.1 1 0 0 1 1 1 1 Mitochondrial fission regulator CAP_N PF01213.14 ETO18587.1 - 0.19 10.9 2.3 0.24 10.6 1.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SMC_N PF02463.14 ETO18588.1 - 2.1e-07 30.3 0.1 0.00087 18.5 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 ETO18588.1 - 1.3e-06 28.5 0.0 7.3e-05 22.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 ETO18588.1 - 0.00015 22.1 5.2 0.88 9.8 0.0 4.8 4 1 1 5 5 5 2 ABC transporter AAA PF00004.24 ETO18588.1 - 0.0002 21.5 0.0 0.64 10.2 0.1 3.1 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETO18588.1 - 0.0002 21.3 0.3 0.027 14.4 0.3 3.2 2 1 0 2 2 2 1 AAA ATPase domain Chromo PF00385.19 ETO18588.1 - 0.0016 18.0 0.3 0.0035 16.9 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SR-25 PF10500.4 ETO18588.1 - 0.0068 15.8 2.6 0.0068 15.8 1.8 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein AAA_14 PF13173.1 ETO18588.1 - 0.0092 15.8 0.1 14 5.5 0.0 3.7 3 1 0 3 3 3 0 AAA domain AAA_24 PF13479.1 ETO18588.1 - 0.014 14.9 5.5 0.78 9.2 0.5 2.9 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 ETO18588.1 - 0.033 14.9 3.3 0.8 10.5 0.4 3.6 3 1 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 ETO18588.1 - 0.04 13.5 1.1 0.15 11.7 0.0 2.4 3 0 0 3 3 2 0 Archaeal ATPase T2SE PF00437.15 ETO18588.1 - 0.041 12.7 0.0 0.1 11.4 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein Acetyltransf_1 PF00583.19 ETO18588.1 - 0.043 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family AAA_29 PF13555.1 ETO18588.1 - 0.061 12.8 0.0 0.18 11.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 ETO18588.1 - 0.11 12.4 0.1 0.11 12.4 0.1 3.2 4 0 0 4 4 3 0 AAA domain PduV-EutP PF10662.4 ETO18588.1 - 0.15 11.5 0.3 3.1 7.2 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 ETO18588.1 - 0.22 11.2 1.1 0.34 10.6 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 ETO18588.1 - 0.24 11.6 2.3 6.1 7.1 0.0 3.2 3 0 0 3 3 2 0 AAA domain Ras PF00071.17 ETO18590.1 - 4e-13 49.0 6.4 4.4e-05 22.9 0.0 4.7 3 1 0 4 4 4 3 Ras family Miro PF08477.8 ETO18590.1 - 2.1e-05 25.0 0.0 0.00048 20.6 0.0 2.9 2 1 0 2 2 2 1 Miro-like protein AAA_14 PF13173.1 ETO18590.1 - 0.056 13.3 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Methyltransf_12 PF08242.7 ETO18590.1 - 0.3 11.5 4.2 0.89 10.0 2.9 1.9 1 0 0 1 1 1 0 Methyltransferase domain Hydrolase PF00702.21 ETO18591.1 - 2.7e-35 122.7 0.0 2.2e-34 119.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 ETO18591.1 - 6.8e-23 81.1 0.3 1.1e-22 80.4 0.2 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 ETO18591.1 - 1e-17 63.8 0.0 2.2e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 ETO18591.1 - 6.3e-15 55.8 0.0 2.4e-14 53.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 ETO18591.1 - 9.8e-07 28.5 0.3 0.002 17.7 0.4 3.1 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 ETO18591.1 - 0.0007 18.6 0.2 0.0013 17.7 0.2 1.5 1 0 0 1 1 1 1 E1-E2 ATPase DEP PF00610.16 ETO18593.1 - 9.9e-12 44.4 0.0 2.7e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) EF-hand_7 PF13499.1 ETO18593.1 - 1.6e-06 28.1 4.6 0.0037 17.3 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO18593.1 - 4.3e-05 23.0 0.3 0.12 12.3 0.0 3.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 ETO18593.1 - 0.0011 18.1 1.8 0.028 13.7 0.0 3.2 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 ETO18593.1 - 0.0027 17.2 2.1 0.037 13.6 0.1 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 ETO18593.1 - 0.0079 15.4 0.1 0.032 13.5 0.1 2.1 1 0 0 1 1 1 1 EF hand Clat_adaptor_s PF01217.15 ETO18594.1 - 1.2e-37 128.8 11.6 1.6e-36 125.1 8.1 2.0 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Ribosomal_S30AE PF02482.14 ETO18594.1 - 0.16 12.4 0.8 0.33 11.4 0.1 1.8 2 0 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein Pkinase PF00069.20 ETO18595.1 - 0.0075 15.4 0.0 2.2 7.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain RRM_5 PF13893.1 ETO18596.1 - 6.7e-05 22.6 0.1 0.00016 21.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO18596.1 - 0.0003 20.3 0.1 0.00067 19.2 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PH PF00169.24 ETO18597.1 - 9e-08 32.2 17.6 4.1e-06 26.9 4.1 3.2 3 1 0 3 3 3 2 PH domain PH_11 PF15413.1 ETO18597.1 - 7.8e-06 26.1 0.4 7.8e-06 26.1 0.3 3.4 3 2 0 3 3 3 1 Pleckstrin homology domain Menin PF05053.8 ETO18597.1 - 0.45 8.6 6.1 0.63 8.1 4.2 1.2 1 0 0 1 1 1 0 Menin SUFU_C PF12470.3 ETO18597.1 - 0.79 9.2 3.6 2.7 7.5 1.7 2.0 2 0 0 2 2 2 0 Suppressor of Fused Gli/Ci N terminal binding domain Pex14_N PF04695.8 ETO18597.1 - 1 9.4 8.1 2.1 8.3 4.2 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PH PF00169.24 ETO18598.1 - 5e-19 68.4 10.0 1.4e-09 38.1 4.4 3.0 2 1 0 2 2 2 2 PH domain PH_11 PF15413.1 ETO18598.1 - 7.4e-13 48.7 6.7 1.1e-05 25.6 0.1 3.2 3 0 0 3 3 3 3 Pleckstrin homology domain PH_8 PF15409.1 ETO18598.1 - 8.4e-11 41.8 0.5 0.0057 16.7 0.0 3.5 3 0 0 3 3 3 3 Pleckstrin homology domain PH_3 PF14593.1 ETO18598.1 - 8.4e-09 35.2 1.8 0.059 13.2 0.0 3.2 3 0 0 3 3 3 3 PH domain E1-E2_ATPase PF00122.15 ETO18599.1 - 2e-34 118.6 1.0 3.8e-34 117.7 0.3 1.6 1 1 1 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.21 ETO18599.1 - 2.2e-14 52.6 0.0 3.5e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF2678 PF10856.3 ETO18599.1 - 0.023 14.4 0.4 0.04 13.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) Rad9 PF04139.8 ETO18600.1 - 1.9e-12 46.8 0.5 5.3e-12 45.4 0.3 1.7 1 0 0 1 1 1 1 Rad9 TMEM190 PF15431.1 ETO18600.1 - 0.0012 18.7 1.0 0.0025 17.7 0.2 1.8 2 0 0 2 2 2 1 Transmembrane protein 190 N_NLPC_P60 PF12912.2 ETO18600.1 - 0.0028 17.7 1.7 0.003 17.6 0.1 1.8 2 0 0 2 2 2 1 NLPC_P60 stabilising domain, N term Rad1 PF02144.11 ETO18600.1 - 0.0042 15.8 0.2 0.0058 15.4 0.2 1.2 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Cytokin-bind PF09265.5 ETO18600.1 - 0.0062 15.7 0.0 0.0075 15.4 0.0 1.1 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding DUF912 PF06024.7 ETO18600.1 - 0.14 12.2 0.3 1 9.4 0.1 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) YajC PF02699.10 ETO18600.1 - 0.25 11.0 0.1 0.25 11.0 0.1 1.7 2 0 0 2 2 2 0 Preprotein translocase subunit LRR_6 PF13516.1 ETO18601.1 - 0.00076 19.3 2.4 0.22 11.6 0.0 2.9 3 0 0 3 3 3 2 Leucine Rich repeat LRR_7 PF13504.1 ETO18601.1 - 0.031 14.4 1.2 22 5.8 0.0 3.5 3 0 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.28 ETO18601.1 - 0.17 11.9 2.8 3 8.2 0.0 3.1 3 1 0 3 3 3 0 Leucine Rich Repeat DUF2116 PF09889.4 ETO18602.1 - 0.1 12.4 0.0 1.6 8.5 0.0 2.6 2 1 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DNA_ligase_A_N PF04675.9 ETO18603.1 - 2.8e-43 147.7 0.3 5e-43 146.9 0.2 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.16 ETO18603.1 - 3.7e-16 59.1 0.5 8.8e-16 57.8 0.0 1.8 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_M PF01068.16 ETO18604.1 - 2.7e-34 118.2 0.0 4.3e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.10 ETO18604.1 - 1.1e-20 73.8 0.0 1.8e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region CIAPIN1 PF05093.8 ETO18605.1 - 3.3e-19 68.8 21.6 1.1e-18 67.2 12.2 2.9 2 1 0 2 2 2 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Methyltransf_23 PF13489.1 ETO18605.1 - 0.0011 18.7 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO18605.1 - 0.01 15.4 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 ETO18605.1 - 0.022 15.2 0.0 0.057 13.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 ETO18605.1 - 0.059 12.4 0.0 0.091 11.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family CD36 PF01130.16 ETO18606.1 - 2.7e-21 75.4 0.0 3.4e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 CD36 family MAT1 PF06391.8 ETO18607.1 - 0.0017 17.9 4.1 0.003 17.1 2.8 1.6 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 Macoilin PF09726.4 ETO18607.1 - 0.0098 14.2 8.8 0.003 15.9 4.2 1.4 2 0 0 2 2 2 1 Transmembrane protein DUF16 PF01519.11 ETO18607.1 - 0.013 15.6 0.9 0.022 14.9 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF342 PF03961.8 ETO18607.1 - 0.014 13.8 1.0 0.017 13.5 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) ACCA PF03255.9 ETO18607.1 - 0.017 14.6 0.6 0.031 13.8 0.4 1.4 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Streptin-Immun PF11083.3 ETO18607.1 - 0.029 14.3 1.9 0.056 13.4 1.3 1.4 1 0 0 1 1 1 0 Lantibiotic streptin immunity protein DivIC PF04977.10 ETO18607.1 - 0.04 13.3 5.9 0.095 12.2 4.1 1.6 1 0 0 1 1 1 0 Septum formation initiator V_ATPase_I PF01496.14 ETO18607.1 - 0.12 10.1 2.5 0.17 9.7 1.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3373 PF11853.3 ETO18607.1 - 0.13 10.7 6.3 0.06 11.8 2.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3373) V-ATPase_C PF03223.10 ETO18607.1 - 0.19 10.6 5.1 0.31 9.9 3.5 1.3 1 0 0 1 1 1 0 V-ATPase subunit C DUF4446 PF14584.1 ETO18607.1 - 0.19 11.5 3.4 0.47 10.2 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Spc24 PF08286.6 ETO18607.1 - 0.39 10.4 6.5 0.13 11.9 2.1 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 XhlA PF10779.4 ETO18607.1 - 0.57 10.1 6.1 0.41 10.5 2.7 2.0 2 0 0 2 2 2 0 Haemolysin XhlA YlqD PF11068.3 ETO18607.1 - 0.64 10.0 7.7 0.1 12.6 2.8 1.6 2 0 0 2 2 1 0 YlqD protein SlyX PF04102.7 ETO18607.1 - 0.67 10.3 7.5 0.29 11.5 3.0 2.0 2 0 0 2 2 2 0 SlyX Fib_alpha PF08702.5 ETO18607.1 - 1.7 8.7 9.9 0.33 11.0 4.1 2.0 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Filo_glycop PF01611.11 ETO18607.1 - 2.4 6.8 10.3 3.2 6.4 7.1 1.2 1 0 0 1 1 1 0 Filovirus glycoprotein IFP_35_N PF07334.8 ETO18607.1 - 3.5 7.6 6.7 1.5 8.8 2.5 2.1 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus ERGIC_N PF13850.1 ETO18609.1 - 3.5e-19 68.5 0.4 7.9e-19 67.4 0.3 1.5 1 1 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) RNA_pol_Rpc34 PF05158.7 ETO18609.1 - 0.015 14.5 0.0 0.021 14.0 0.0 1.3 1 1 0 1 1 1 0 RNA polymerase Rpc34 subunit FDF PF09532.5 ETO18610.1 - 2 9.0 7.4 3.7 8.1 5.1 1.7 1 1 0 1 1 1 0 FDF domain YqzE PF14038.1 ETO18611.1 - 0.37 10.5 2.2 0.72 9.6 1.5 1.4 1 0 0 1 1 1 0 YqzE-like protein ER_lumen_recept PF00810.13 ETO18613.1 - 0.027 14.9 1.8 0.06 13.8 1.3 1.6 1 0 0 1 1 1 0 ER lumen protein retaining receptor Myosin_head PF00063.16 ETO18614.1 - 1.4e-24 86.1 0.0 1.9e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) WW PF00397.21 ETO18614.1 - 2e-08 33.9 2.6 5e-08 32.6 1.1 2.1 2 0 0 2 2 2 1 WW domain CTD_bind PF04818.8 ETO18615.1 - 0.00023 21.3 2.4 0.00025 21.2 0.7 1.8 1 1 0 1 1 1 1 RNA polymerase II-binding domain. PAZ_siRNAbind PF12212.3 ETO18615.1 - 0.067 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Piwi/Argonaute/Zwille siRNA-binding domain Zip PF02535.17 ETO18615.1 - 0.083 11.8 0.3 0.072 12.0 0.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3395 PF11875.3 ETO18616.1 - 1.1e-11 44.5 0.0 1.1e-11 44.5 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3395) Utp14 PF04615.8 ETO18616.1 - 0.085 11.0 25.7 0.12 10.5 17.8 1.1 1 0 0 1 1 1 0 Utp14 protein DUF4118 PF13493.1 ETO18617.1 - 0.024 14.8 0.8 0.053 13.7 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) DUF1987 PF09345.5 ETO18618.1 - 0.2 11.4 1.7 0.43 10.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1987) ubiquitin PF00240.18 ETO18620.1 - 3.9e-40 135.0 0.8 1.3e-29 101.3 0.2 2.6 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 ETO18620.1 - 1.7e-23 82.1 0.5 1.9e-17 62.6 0.2 2.7 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Hint PF01079.15 ETO18620.1 - 1.6e-07 30.7 0.2 4.2e-07 29.3 0.1 1.7 1 1 0 1 1 1 1 Hint module AXH PF08517.7 ETO18620.1 - 4.3e-07 30.0 0.1 1.5e-06 28.3 0.0 2.0 1 0 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) Ubiquitin_2 PF14560.1 ETO18620.1 - 4.8e-07 29.9 0.5 1.6e-05 25.0 0.0 2.9 2 0 0 2 2 2 1 Ubiquitin-like domain PT-HINT PF07591.6 ETO18620.1 - 4.4e-06 26.6 6.3 7.1e-06 25.9 2.3 2.7 2 1 0 2 2 2 1 Pretoxin HINT domain Hint_2 PF13403.1 ETO18620.1 - 0.00075 19.4 0.1 0.002 18.0 0.0 1.8 1 0 0 1 1 1 1 Hint domain Hom_end_hint PF05203.11 ETO18620.1 - 0.0009 19.0 0.1 0.0009 19.0 0.0 2.6 2 0 0 2 2 2 1 Hom_end-associated Hint DUF2407 PF10302.4 ETO18620.1 - 0.0044 17.1 4.5 1.8 8.7 0.0 3.4 3 1 0 3 3 3 2 DUF2407 ubiquitin-like domain FAM176 PF14851.1 ETO18620.1 - 0.014 15.0 3.0 0.033 13.8 2.0 1.7 1 0 0 1 1 1 0 FAM176 family Rad60-SLD_2 PF13881.1 ETO18620.1 - 0.057 13.3 0.0 0.057 13.3 0.0 2.8 2 1 1 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like Spot_14 PF07084.7 ETO18620.1 - 0.11 12.3 3.1 0.78 9.5 0.7 2.7 3 0 0 3 3 3 0 Thyroid hormone-inducible hepatic protein Spot 14 Sporozoite_P67 PF05642.6 ETO18620.1 - 0.13 10.1 5.1 0.19 9.5 3.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CENP-B_dimeris PF09026.5 ETO18620.1 - 0.41 10.8 7.8 1.4 9.2 5.4 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 ETO18620.1 - 0.45 10.0 12.8 0.85 9.1 8.9 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region BSP_II PF05432.6 ETO18620.1 - 0.63 9.2 12.0 1 8.5 8.3 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) RNA_pol_3_Rpc31 PF11705.3 ETO18620.1 - 0.92 9.3 13.8 2.6 7.9 9.6 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Daxx PF03344.10 ETO18620.1 - 2.1 6.7 11.8 3.1 6.1 8.2 1.1 1 0 0 1 1 1 0 Daxx Family DUF4191 PF13829.1 ETO18622.1 - 0.17 10.9 0.1 0.39 9.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Methyltransf_11 PF08241.7 ETO18623.1 - 3.4e-17 62.7 0.0 4.4e-16 59.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO18623.1 - 3e-14 53.2 0.1 1.3e-13 51.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO18623.1 - 2.5e-12 46.6 0.1 1.3e-11 44.2 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETO18623.1 - 2e-11 43.8 0.0 2.8e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETO18623.1 - 8.6e-11 41.8 0.0 1.7e-10 40.9 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETO18623.1 - 1.1e-10 41.7 0.3 1.3e-09 38.3 0.0 2.5 2 2 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO18623.1 - 4e-10 40.2 0.0 1.1e-09 38.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 ETO18623.1 - 7.2e-05 22.8 1.4 0.0014 18.6 0.0 2.8 2 1 0 2 2 2 1 FtsJ-like methyltransferase MetW PF07021.7 ETO18623.1 - 0.00057 19.3 0.1 0.00084 18.7 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 ETO18623.1 - 0.00078 18.8 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 ETO18623.1 - 0.0022 17.1 0.7 0.015 14.4 0.0 1.9 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.6 ETO18623.1 - 0.0042 15.8 0.1 0.0067 15.1 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) RrnaAD PF00398.15 ETO18623.1 - 0.015 14.3 0.0 0.018 14.0 0.0 1.4 1 1 0 1 1 1 0 Ribosomal RNA adenine dimethylase AdoMet_MTase PF07757.8 ETO18623.1 - 0.069 13.2 0.4 0.13 12.3 0.3 1.5 1 1 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase DUF4576 PF15144.1 ETO18623.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) FimP PF09766.4 ETO18624.1 - 0.00067 18.8 19.6 0.00067 18.8 13.6 2.1 2 0 0 2 2 2 1 Fms-interacting protein Suf PF05843.9 ETO18624.1 - 0.0022 17.7 14.0 0.0022 17.7 9.7 2.2 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) VIT1 PF01988.14 ETO18624.1 - 0.4 10.1 2.0 1.5 8.2 0.5 2.1 2 0 0 2 2 2 0 VIT family Tim54 PF11711.3 ETO18624.1 - 0.44 9.0 7.9 0.16 10.4 0.5 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF3439 PF11921.3 ETO18624.1 - 0.45 10.2 6.5 0.48 10.1 2.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) CagX PF03524.10 ETO18624.1 - 0.7 9.1 15.0 0.16 11.2 3.2 2.5 2 0 0 2 2 2 0 Conjugal transfer protein BRF1 PF07741.8 ETO18624.1 - 0.78 10.0 14.5 0.26 11.5 4.1 2.4 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Bud13 PF09736.4 ETO18624.1 - 0.93 9.7 21.6 0.7 10.1 8.0 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex DUF4557 PF15101.1 ETO18624.1 - 1.8 8.3 31.8 0.076 12.8 10.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) FAM176 PF14851.1 ETO18624.1 - 2.2 7.9 7.2 1.1 8.9 1.4 2.3 2 0 0 2 2 2 0 FAM176 family Peptidase_S15 PF02129.13 ETO18624.1 - 4 6.7 17.8 0.039 13.3 4.1 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF1764 PF08576.5 ETO18624.1 - 4.4 8.1 18.8 0.86 10.4 5.7 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) RR_TM4-6 PF06459.7 ETO18624.1 - 4.5 7.0 15.3 0.08 12.8 3.0 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 RED_N PF07808.8 ETO18624.1 - 5.1 6.2 34.4 0.068 12.3 12.6 2.2 2 0 0 2 2 2 0 RED-like protein N-terminal region EPL1 PF10513.4 ETO18624.1 - 6.2 7.0 21.6 0.76 10.0 6.2 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like MIF4G PF02854.14 ETO18625.1 - 1e-12 47.8 0.3 1e-12 47.8 0.2 2.1 2 0 0 2 2 2 1 MIF4G domain PAM2 PF07145.10 ETO18625.1 - 6.7e-05 22.1 0.1 6.7e-05 22.1 0.0 2.6 3 0 0 3 3 3 1 Ataxin-2 C-terminal region MIF4G PF02854.14 ETO18626.1 - 7.5e-09 35.2 2.5 1.9e-08 33.9 1.7 1.7 1 0 0 1 1 1 1 MIF4G domain rve PF00665.21 ETO18626.1 - 0.09 12.8 0.1 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain YgaB PF14182.1 ETO18626.1 - 2.2 8.6 6.7 0.72 10.1 0.8 2.6 2 1 1 3 3 3 0 YgaB-like protein TPT PF03151.11 ETO18627.1 - 5.8e-21 74.7 7.1 9.1e-21 74.1 4.9 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.6 ETO18627.1 - 6e-06 25.3 2.0 8e-06 24.9 1.4 1.2 1 0 0 1 1 1 1 UAA transporter family RunxI PF08504.6 ETO18627.1 - 0.088 13.2 0.0 11 6.5 0.0 2.3 2 0 0 2 2 2 0 Runx inhibition domain EamA PF00892.15 ETO18627.1 - 0.18 11.8 10.4 1.4 8.9 7.2 2.2 1 1 0 1 1 1 0 EamA-like transporter family Sterile PF03015.14 ETO18628.1 - 0.14 12.3 3.1 16 5.8 0.1 3.0 2 0 0 2 2 2 0 Male sterility protein PRO8NT PF08082.6 ETO18630.1 - 6.3e-29 100.5 0.4 6.3e-29 100.5 0.3 1.4 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain PRO8NT PF08082.6 ETO18631.1 - 1.2e-26 93.1 1.1 2.2e-26 92.3 0.7 1.4 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain ABC_membrane PF00664.18 ETO18632.1 - 0.0059 16.0 2.2 0.009 15.4 1.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF2207 PF09972.4 ETO18632.1 - 0.038 12.5 0.0 0.038 12.5 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) vMSA PF00695.14 ETO18632.1 - 0.066 12.3 4.0 0.075 12.2 2.8 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus P12 PF12669.2 ETO18632.1 - 0.071 13.3 0.8 0.071 13.3 0.5 2.2 2 0 0 2 2 2 0 Virus attachment protein p12 family DUF4131 PF13567.1 ETO18632.1 - 0.21 10.9 3.6 0.29 10.5 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) WBP-1 PF11669.3 ETO18632.1 - 0.25 11.4 6.4 0.47 10.5 4.4 1.4 1 0 0 1 1 1 0 WW domain-binding protein 1 YajC PF02699.10 ETO18632.1 - 0.33 10.6 1.9 0.5 10.0 1.3 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit SIT PF15330.1 ETO18632.1 - 0.81 9.8 5.9 1.7 8.7 4.1 1.5 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Rifin_STEVOR PF02009.11 ETO18632.1 - 2.3 7.7 8.3 7 6.1 5.7 1.7 1 1 0 1 1 1 0 Rifin/stevor family DUF912 PF06024.7 ETO18632.1 - 6.3 6.9 7.4 10 6.2 5.1 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) RabGAP-TBC PF00566.13 ETO18633.1 - 9.9e-20 70.9 2.5 9.9e-20 70.9 1.7 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain PBP_sp32 PF07222.7 ETO18633.1 - 2.1 7.4 10.2 3.2 6.8 7.1 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 IncA PF04156.9 ETO18633.1 - 7.5 6.0 8.2 6.2 6.3 4.8 1.4 2 0 0 2 2 2 0 IncA protein zf-SAP30 PF13866.1 ETO18635.1 - 1 9.0 4.1 5.4 6.7 2.1 2.1 2 0 0 2 2 2 0 SAP30 zinc-finger PAP_central PF04928.12 ETO18636.1 - 4.3e-33 114.1 0.7 4.9e-33 113.9 0.5 1.0 1 0 0 1 1 1 1 Poly(A) polymerase central domain Ank_2 PF12796.2 ETO18637.1 - 8.4e-07 29.2 0.0 2.4e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO18637.1 - 1.7e-06 27.6 0.0 0.12 12.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 ETO18637.1 - 7.3e-06 26.3 0.0 0.0009 19.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 ETO18637.1 - 0.001 18.7 0.0 0.032 14.0 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 ETO18637.1 - 0.017 15.3 0.0 0.08 13.2 0.0 2.1 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Fer4_9 PF13187.1 ETO18637.1 - 0.056 13.7 0.8 0.12 12.6 0.5 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain cNMP_binding PF00027.24 ETO18639.1 - 3.5e-19 68.3 0.0 5.7e-18 64.5 0.0 2.2 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Pkinase PF00069.20 ETO18639.1 - 1.1e-12 47.6 0.0 2e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO18639.1 - 1e-05 24.7 0.0 1.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Casc1 PF12366.3 ETO18639.1 - 0.42 10.0 3.7 4.5 6.6 0.0 2.1 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 Pkinase PF00069.20 ETO18640.1 - 5e-17 61.9 0.1 6.2e-16 58.3 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO18640.1 - 0.0003 19.9 0.0 0.033 13.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Ferrochelatase PF00762.14 ETO18641.1 - 0.0017 17.3 1.0 0.0022 17.0 0.7 1.2 1 0 0 1 1 1 1 Ferrochelatase Selenoprotein_S PF06936.6 ETO18641.1 - 3.9 6.9 6.2 3.7 7.0 3.3 1.7 1 1 1 2 2 2 0 Selenoprotein S (SelS) OPA3 PF07047.7 ETO18641.1 - 5.2 6.8 7.8 3.9 7.2 0.1 2.4 2 0 0 2 2 2 0 Optic atrophy 3 protein (OPA3) Menin PF05053.8 ETO18642.1 - 6.9 4.7 12.4 7.5 4.5 8.6 1.2 1 0 0 1 1 1 0 Menin Abhydrolase_6 PF12697.2 ETO18644.1 - 0.03 14.1 0.0 0.04 13.7 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Zip PF02535.17 ETO18645.1 - 0.23 10.4 0.9 0.25 10.2 0.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PBP_sp32 PF07222.7 ETO18645.1 - 1.2 8.2 6.4 2 7.5 4.4 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Med10 PF09748.4 ETO18646.1 - 0.076 12.8 0.1 0.076 12.8 0.0 1.2 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex TauE PF01925.14 ETO18649.1 - 2.3e-13 50.1 0.5 2.7e-13 49.9 0.4 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE YbhQ PF11076.3 ETO18649.1 - 0.0031 17.1 0.2 0.0055 16.3 0.1 1.4 1 0 0 1 1 1 1 Putative inner membrane protein YbhQ DUF3278 PF11683.3 ETO18649.1 - 0.012 15.6 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) SpoIIIAH PF12685.2 ETO18649.1 - 0.025 14.0 0.1 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF2955 PF11168.3 ETO18649.1 - 0.1 12.2 4.0 1.3 8.6 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2955) Bax1-I PF01027.15 ETO18649.1 - 0.12 11.9 4.9 0.17 11.4 3.4 1.2 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF3154 PF11351.3 ETO18649.1 - 0.14 11.9 0.1 0.14 11.9 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) NADH-G_4Fe-4S_3 PF10588.4 ETO18649.1 - 1.8 7.8 10.0 0.55 9.5 0.1 2.5 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Hexokinase_1 PF00349.16 ETO18650.1 - 7.3e-24 84.2 0.3 1e-23 83.7 0.2 1.1 1 0 0 1 1 1 1 Hexokinase Pkinase PF00069.20 ETO18651.1 - 6.9e-59 199.1 0.0 6.8e-58 195.8 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO18651.1 - 6.2e-26 91.0 0.5 2.4e-24 85.7 0.3 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 ETO18651.1 - 0.00053 19.1 0.0 0.0013 17.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETO18651.1 - 0.0061 15.5 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETO18651.1 - 0.019 14.7 0.4 0.037 13.7 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Acyl-ACP_TE PF01643.12 ETO18653.1 - 0.003 16.5 0.2 0.006 15.5 0.1 1.6 1 1 0 1 1 1 1 Acyl-ACP thioesterase BpuSI_N PF15516.1 ETO18653.1 - 0.069 12.8 0.1 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 BpuSI N-terminal domain DUF3391 PF11871.3 ETO18653.1 - 0.69 10.1 3.2 18 5.5 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) Kelch_6 PF13964.1 ETO18654.1 - 8.4e-06 25.7 1.2 0.13 12.5 0.0 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO18654.1 - 0.032 14.1 0.1 6.7 6.7 0.0 4.0 5 0 0 5 5 5 0 Kelch motif Kelch_3 PF13415.1 ETO18654.1 - 0.099 12.8 0.1 0.68 10.1 0.0 2.5 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO18654.1 - 0.16 11.5 2.4 4 7.0 0.2 3.4 3 0 0 3 3 3 0 Kelch motif DUF1151 PF06625.6 ETO18656.1 - 0.14 11.9 9.2 0.15 11.7 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) MRP PF09387.5 ETO18656.1 - 0.2 11.3 3.7 0.21 11.2 2.6 1.3 1 0 0 1 1 1 0 Mitochondrial RNA binding protein MRP HEAT_2 PF13646.1 ETO18657.1 - 1.4e-12 47.7 0.0 6.5e-06 26.3 0.0 2.0 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 ETO18657.1 - 5.4e-11 41.6 0.0 0.00022 21.0 0.0 3.5 3 0 0 3 3 3 2 HEAT repeat Cnd1 PF12717.2 ETO18657.1 - 2.2e-06 27.6 0.5 2e-05 24.4 0.2 2.5 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 ETO18657.1 - 0.00045 20.6 0.0 1.2 9.6 0.0 2.7 2 1 0 2 2 2 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 ETO18657.1 - 0.002 18.4 0.1 2.2 8.7 0.0 2.6 1 1 2 3 3 3 2 Vacuolar 14 Fab1-binding region MOR2-PAG1_C PF14225.1 ETO18657.1 - 0.0069 16.1 0.6 0.59 9.8 0.1 2.3 1 1 2 3 3 3 2 Cell morphogenesis C-terminal HrcA PF01628.16 ETO18657.1 - 0.0072 15.9 0.8 0.65 9.5 0.1 2.3 1 1 0 2 2 2 1 HrcA protein C terminal domain Gp-FAR-1 PF05823.7 ETO18657.1 - 0.0077 16.2 1.3 0.023 14.6 0.4 2.1 1 1 1 2 2 2 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF2435 PF10363.4 ETO18657.1 - 0.0078 16.0 0.0 0.053 13.4 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF2435) TIP120 PF08623.5 ETO18657.1 - 0.0096 15.5 1.7 0.28 10.7 0.2 2.8 1 1 2 3 3 3 1 TATA-binding protein interacting (TIP20) TAN PF11640.3 ETO18657.1 - 0.018 14.7 1.3 0.44 10.2 0.2 2.8 1 1 1 2 2 2 0 Telomere-length maintenance and DNA damage repair Fe-S_assembly PF04384.8 ETO18657.1 - 0.052 13.9 3.4 0.81 10.0 0.1 3.1 2 1 1 3 3 3 0 Iron-sulphur cluster assembly MSP7_C PF12948.2 ETO18657.1 - 1 9.6 9.1 6.9 6.9 0.4 3.3 2 2 1 3 3 3 0 MSP7-like protein C-terminal domain Baculo_LEF5 PF04838.7 ETO18657.1 - 2.1 8.1 6.1 1.5 8.5 0.2 2.1 1 1 1 2 2 2 0 Baculoviridae late expression factor 5 SAM_2 PF07647.12 ETO18658.1 - 1.5e-07 31.1 0.2 2e-07 30.7 0.2 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO18658.1 - 1.1e-05 25.4 0.4 1.6e-05 25.0 0.3 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Cyclin PF08613.6 ETO18658.1 - 0.017 15.5 0.2 0.024 15.0 0.1 1.3 1 0 0 1 1 1 0 Cyclin BAF PF02961.9 ETO18658.1 - 0.022 15.0 0.1 0.037 14.3 0.1 1.4 1 0 0 1 1 1 0 Barrier to autointegration factor WD40 PF00400.27 ETO18659.1 - 3.3e-81 264.5 17.8 1.6e-12 46.8 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO18659.1 - 9.9e-08 30.5 7.0 0.12 10.4 0.0 4.8 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO18659.1 - 6e-06 25.2 5.8 0.094 11.4 0.7 4.2 1 1 2 3 3 3 3 Nup133 N terminal like Nbas_N PF15492.1 ETO18659.1 - 0.00019 20.6 2.4 1.2 8.1 0.0 4.0 1 1 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal DUF3312 PF11768.3 ETO18659.1 - 0.0034 15.7 0.0 0.2 9.8 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3312) PD40 PF07676.7 ETO18659.1 - 0.01 15.5 7.9 21 4.9 0.0 5.1 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO18659.1 - 0.015 14.7 0.7 1.2 8.5 0.1 2.2 1 1 1 2 2 2 0 PQQ-like domain Pectate_lyase22 PF14583.1 ETO18659.1 - 0.035 12.5 0.0 0.67 8.3 0.0 2.1 2 0 0 2 2 2 0 Oligogalacturonate lyase TolB_N PF04052.8 ETO18659.1 - 0.042 13.9 0.0 33 4.6 0.0 4.6 5 0 0 5 5 5 0 TolB amino-terminal domain PS_Dcarbxylase PF02666.10 ETO18659.1 - 0.058 12.6 0.0 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 Phosphatidylserine decarboxylase PUF PF00806.14 ETO18660.1 - 3.7e-38 126.8 16.9 1.5e-06 27.3 0.2 8.7 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Nop14 PF04147.7 ETO18660.1 - 0.0021 16.0 1.5 0.0034 15.4 1.0 1.2 1 0 0 1 1 1 1 Nop14-like family Cpn60_TCP1 PF00118.19 ETO18661.1 - 9.4e-39 133.3 1.7 1e-38 133.1 1.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SOG2 PF10428.4 ETO18662.1 - 0.053 12.1 7.8 0.054 12.1 5.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.4 ETO18662.1 - 7.5 4.7 6.6 11 4.1 4.5 1.2 1 0 0 1 1 1 0 Transmembrane protein VSP PF03302.8 ETO18663.1 - 0.054 12.1 1.1 0.077 11.6 0.8 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Shisa PF13908.1 ETO18663.1 - 0.08 13.1 1.0 0.14 12.3 0.7 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator WD40 PF00400.27 ETO18664.1 - 5.4e-58 190.9 27.2 9.4e-11 41.1 1.3 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO18664.1 - 1.5e-13 49.8 4.9 4.5e-05 21.7 0.1 5.5 3 1 2 5 5 5 5 Nucleoporin Nup120/160 Ricin_B_lectin PF00652.17 ETO18664.1 - 1.3 9.0 14.7 1.7 8.7 1.3 4.0 4 1 0 4 4 4 0 Ricin-type beta-trefoil lectin domain Auxin_repressed PF05564.7 ETO18665.1 - 0.013 16.0 1.4 0.017 15.6 1.0 1.3 1 0 0 1 1 1 0 Dormancy/auxin associated protein Rtf2 PF04641.7 ETO18665.1 - 2.7 7.1 10.6 3.3 6.8 7.3 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF2291 PF10054.4 ETO18666.1 - 0.086 12.1 0.6 0.13 11.5 0.4 1.2 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2291) Cupin_8 PF13621.1 ETO18668.1 - 4.3e-23 82.1 0.3 6.8e-23 81.4 0.2 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 ETO18668.1 - 3.3e-08 33.1 0.7 0.00042 19.6 0.1 2.4 2 1 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 ETO18668.1 - 0.0025 18.0 1.0 0.015 15.5 0.5 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase GPI PF06560.6 ETO18668.1 - 0.12 11.3 0.0 0.26 10.2 0.0 1.5 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) MoaF PF10703.4 ETO18669.1 - 0.023 13.7 0.1 0.028 13.4 0.1 1.1 1 0 0 1 1 1 0 Molybdenum cofactor biosynthesis protein F Rep_fac-A_C PF08646.5 ETO18670.1 - 7.6e-13 48.4 1.6 3e-12 46.4 0.0 2.4 1 1 1 2 2 2 1 Replication factor-A C terminal domain BAF1_ABF1 PF04684.8 ETO18670.1 - 3.2 6.4 10.7 0.049 12.4 2.3 1.6 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF1211 PF06736.6 ETO18671.1 - 0.022 14.8 2.3 0.054 13.6 1.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1211) DUF2721 PF11026.3 ETO18671.1 - 0.21 11.2 3.2 0.68 9.5 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) TLD PF07534.11 ETO18672.1 - 1e-27 96.8 0.2 1e-27 96.8 0.2 1.9 2 0 0 2 2 2 1 TLD DUF3446 PF11928.3 ETO18672.1 - 0.067 13.3 32.2 0.15 12.2 5.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) Chorion_2 PF03964.10 ETO18672.1 - 0.97 10.0 8.6 4.5 7.8 2.8 2.3 2 0 0 2 2 2 0 Chorion family 2 WD40 PF00400.27 ETO18673.1 - 9e-21 72.9 13.5 3.3e-07 29.9 0.1 5.3 5 1 0 5 5 5 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO18673.1 - 0.0083 14.9 8.3 0.44 9.2 0.1 2.2 1 1 1 2 2 2 2 Nup133 N terminal like CblD PF07434.6 ETO18673.1 - 0.023 13.3 2.9 0.12 10.9 0.1 2.2 2 0 0 2 2 2 0 CblD like pilus biogenesis initiator Spore_YhcN_YlaJ PF09580.5 ETO18674.1 - 0.012 15.7 0.9 0.012 15.7 0.6 3.3 3 0 0 3 3 3 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF1981 PF09324.5 ETO18674.1 - 0.02 14.3 0.5 3.9 7.0 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) DUF2732 PF10809.3 ETO18675.1 - 0.15 11.6 3.0 0.12 11.9 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2732) DUF4615 PF15393.1 ETO18675.1 - 3.9 7.7 13.0 2.8 8.1 2.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4615) GCD14 PF08704.5 ETO18675.1 - 8.9 5.7 7.7 3.8 6.9 3.6 1.6 1 1 1 2 2 2 0 tRNA methyltransferase complex GCD14 subunit DFP PF04127.10 ETO18676.1 - 1 8.9 6.2 1.1 8.8 4.3 1.0 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Sec39 PF08314.6 ETO18678.1 - 0.00035 18.6 0.4 0.00055 18.0 0.3 1.2 1 0 0 1 1 1 1 Secretory pathway protein Sec39 DUF3211 PF11485.3 ETO18680.1 - 0.16 11.9 2.7 0.13 12.3 0.9 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3211) DUF2508 PF10704.4 ETO18680.1 - 1.7 8.8 8.5 1.7 8.8 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) Pkinase PF00069.20 ETO18681.1 - 1.4e-06 27.6 0.0 1.5e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF4201 PF13870.1 ETO18681.1 - 0.025 14.0 0.8 0.043 13.2 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) ECH PF00378.15 ETO18681.1 - 0.11 11.5 0.3 1.3 8.0 0.1 1.9 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase family DUF4023 PF13215.1 ETO18681.1 - 0.77 9.5 3.2 0.33 10.7 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4023) Pkinase PF00069.20 ETO18682.1 - 1.4e-41 142.3 0.1 1.8e-41 141.9 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO18682.1 - 8.2e-18 64.4 0.0 1e-17 64.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETO18682.1 - 1.8e-05 24.6 0.0 3.2e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 ETO18682.1 - 0.00093 18.2 0.0 0.0012 17.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 ETO18682.1 - 0.0012 18.4 0.1 0.0016 18.0 0.1 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 ETO18682.1 - 0.048 12.4 0.0 0.085 11.6 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 ETO18682.1 - 0.05 12.6 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kelch_1 PF01344.20 ETO18683.1 - 0.068 12.7 0.8 0.48 10.0 0.0 2.8 2 1 0 2 2 2 0 Kelch motif NnrU PF07298.6 ETO18684.1 - 0.076 12.3 0.5 0.14 11.5 0.2 1.4 1 1 0 1 1 1 0 NnrU protein Peptidase_M13_N PF05649.8 ETO18685.1 - 0.0073 15.3 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 Daxx PF03344.10 ETO18686.1 - 0.095 11.1 16.2 0.14 10.6 11.2 1.2 1 0 0 1 1 1 0 Daxx Family TRAP_alpha PF03896.11 ETO18686.1 - 0.28 10.1 5.7 2.2 7.2 3.9 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.8 ETO18686.1 - 4.1 5.0 13.6 6.1 4.4 9.4 1.3 1 0 0 1 1 1 0 DNA polymerase phi Ycf1 PF05758.7 ETO18687.1 - 0.062 11.0 15.5 0.072 10.7 10.8 1.1 1 0 0 1 1 1 0 Ycf1 Pox_Ag35 PF03286.9 ETO18687.1 - 0.072 12.6 26.6 0.1 12.1 18.4 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Daxx PF03344.10 ETO18687.1 - 0.17 10.3 16.8 0.2 10.1 11.6 1.0 1 0 0 1 1 1 0 Daxx Family SAPS PF04499.10 ETO18687.1 - 0.94 8.0 14.9 1.2 7.6 10.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NPR3 PF03666.8 ETO18687.1 - 1.7 7.0 19.3 2.2 6.7 13.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Neur_chan_memb PF02932.11 ETO18687.1 - 2.9 7.7 9.4 4.5 7.0 6.5 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PLRV_ORF5 PF01690.12 ETO18687.1 - 6.5 5.7 17.8 8.2 5.4 12.4 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein CDC45 PF02724.9 ETO18687.1 - 7 4.5 18.6 8.4 4.2 12.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Dsh_C PF12316.3 ETO18687.1 - 8.6 6.4 10.2 11 6.0 7.1 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal SMN PF06003.7 ETO18688.1 - 0.57 9.2 10.5 0.09 11.8 2.7 2.0 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) Sec63 PF02889.11 ETO18689.1 - 2.6e-144 480.2 10.5 1e-97 327.1 0.8 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 ETO18689.1 - 7.1e-45 152.5 0.0 1.9e-27 95.8 0.1 2.9 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 ETO18689.1 - 2.2e-09 37.4 1.6 1e-07 31.9 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 ETO18689.1 - 1.5e-06 27.9 0.0 5.4e-06 26.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pkinase PF00069.20 ETO18690.1 - 6.7e-06 25.4 0.2 6.7e-06 25.4 0.1 1.5 2 0 0 2 2 2 1 Protein kinase domain BSP_II PF05432.6 ETO18690.1 - 0.07 12.4 5.9 0.1 11.8 4.1 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Pkinase PF00069.20 ETO18691.1 - 8.3e-43 146.4 0.7 5.7e-42 143.6 0.5 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO18691.1 - 4.4e-19 68.5 0.5 9.7e-19 67.4 0.4 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.14 ETO18691.1 - 6e-13 48.9 1.4 1.4e-10 41.3 1.0 2.8 1 1 0 1 1 1 1 Regulator of G protein signaling domain SAC3 PF12209.3 ETO18691.1 - 0.96 9.6 5.3 0.84 9.8 0.2 3.2 2 0 0 2 2 2 0 Leucine permease transcriptional regulator helical domain Abhydrolase_6 PF12697.2 ETO18693.1 - 9.7e-10 38.7 0.0 1e-09 38.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETO18693.1 - 0.00089 19.0 0.0 0.001 18.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 ETO18693.1 - 0.0048 16.2 0.0 0.0066 15.7 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF2305 PF10230.4 ETO18693.1 - 0.017 14.5 0.0 0.022 14.1 0.0 1.3 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) FtsX PF02687.16 ETO18693.1 - 0.06 13.1 0.7 0.097 12.4 0.2 1.6 2 0 0 2 2 2 0 FtsX-like permease family Pyr_redox_3 PF13738.1 ETO18695.1 - 8.4e-06 25.9 0.0 1.1e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETO18695.1 - 1.8e-05 24.6 0.1 3.4e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Mqo PF06039.10 ETO18695.1 - 0.003 15.8 0.2 0.0037 15.5 0.1 1.1 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) Amino_oxidase PF01593.19 ETO18695.1 - 0.0052 15.9 0.0 0.024 13.7 0.0 1.8 1 1 0 2 2 2 1 Flavin containing amine oxidoreductase tRNA_SAD PF07973.9 ETO18696.1 - 3.4e-15 55.6 0.1 5.2e-15 55.0 0.1 1.3 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.14 ETO18697.1 - 5.3e-201 668.6 0.8 8.2e-201 668.0 0.6 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) Rad10 PF03834.9 ETO18698.1 - 5.5e-22 77.2 0.3 8.1e-22 76.6 0.2 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 ETO18699.1 - 9.3e-09 35.3 0.1 1.3e-08 34.9 0.1 1.2 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.2 ETO18699.1 - 2.2e-08 33.8 0.0 3.9e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.18 ETO18699.1 - 0.00061 19.3 0.1 0.001 18.6 0.1 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_3 PF12836.2 ETO18699.1 - 0.0056 16.5 0.1 0.01 15.7 0.0 1.5 1 1 0 1 1 1 1 Helix-hairpin-helix motif Ufd2P_core PF10408.4 ETO18700.1 - 0.0026 16.0 1.7 0.0029 15.9 1.2 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core DUF4414 PF14377.1 ETO18700.1 - 0.015 15.1 0.1 0.03 14.2 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4414) Sas10_Utp3 PF04000.10 ETO18700.1 - 0.026 14.7 1.5 0.039 14.1 0.2 1.8 2 0 0 2 2 2 0 Sas10/Utp3/C1D family zf-3CxxC PF13695.1 ETO18700.1 - 0.16 12.2 2.2 0.21 11.8 0.1 2.0 2 1 0 2 2 2 0 Zinc-binding domain DUF4200 PF13863.1 ETO18700.1 - 0.62 10.0 9.8 0.043 13.7 2.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF666 PF05006.7 ETO18701.1 - 0.087 12.8 0.4 0.19 11.7 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF666) IBN_N PF03810.14 ETO18701.1 - 0.37 10.7 3.1 0.27 11.1 0.2 2.2 3 0 0 3 3 3 0 Importin-beta N-terminal domain AAA_5 PF07728.9 ETO18702.1 - 5.2e-05 23.0 0.0 8.4e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) WD40 PF00400.27 ETO18703.1 - 2.8e-20 71.3 5.8 7e-08 32.0 0.5 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO18703.1 - 0.011 13.9 0.9 0.32 9.0 0.6 2.5 1 1 1 2 2 2 0 Nucleoporin Nup120/160 DUF2559 PF10832.3 ETO18703.1 - 0.28 11.0 1.1 2.6 7.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2559) Adaptin_binding PF10199.4 ETO18704.1 - 0.0031 17.8 6.3 0.0035 17.6 4.3 1.1 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 RRN3 PF05327.6 ETO18704.1 - 0.027 12.5 2.3 0.031 12.4 1.6 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Vfa1 PF08432.5 ETO18704.1 - 0.049 13.6 8.6 0.052 13.5 6.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FAM60A PF15396.1 ETO18704.1 - 0.066 12.9 9.7 0.079 12.6 6.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A FimP PF09766.4 ETO18704.1 - 0.16 10.9 8.2 0.19 10.7 5.7 1.1 1 0 0 1 1 1 0 Fms-interacting protein FixO PF02433.10 ETO18704.1 - 0.27 10.5 2.5 0.29 10.4 1.7 1.1 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO DUF4619 PF15398.1 ETO18704.1 - 0.3 10.4 7.9 0.32 10.3 5.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4619) NARP1 PF12569.3 ETO18704.1 - 0.31 9.7 8.2 0.33 9.6 5.7 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SUFU_C PF12470.3 ETO18704.1 - 0.33 10.5 4.4 0.38 10.3 3.1 1.1 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain DUF3807 PF12720.2 ETO18704.1 - 0.45 10.6 8.7 0.5 10.4 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF2413 PF10310.4 ETO18704.1 - 0.55 8.9 11.2 0.62 8.8 7.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) RP-C_C PF11800.3 ETO18704.1 - 0.79 9.3 5.0 0.91 9.1 3.5 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Rtf2 PF04641.7 ETO18704.1 - 0.83 8.7 15.2 0.93 8.6 10.6 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Striatin PF08232.7 ETO18704.1 - 0.86 9.9 9.4 1.1 9.5 6.5 1.2 1 0 0 1 1 1 0 Striatin family DUF4551 PF15087.1 ETO18704.1 - 1 7.6 6.5 1.1 7.5 4.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Neur_chan_memb PF02932.11 ETO18704.1 - 1.4 8.7 6.7 1.6 8.5 4.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1754 PF08555.5 ETO18704.1 - 1.5 9.4 19.4 1.9 9.1 13.4 1.2 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Mem_trans PF03547.13 ETO18704.1 - 1.6 6.9 5.4 1.8 6.7 3.8 1.0 1 0 0 1 1 1 0 Membrane transport protein FLO_LFY PF01698.11 ETO18704.1 - 1.8 7.3 8.7 2 7.1 6.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein NST1 PF13945.1 ETO18704.1 - 3.2 7.7 14.4 4.1 7.4 10.0 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Presenilin PF01080.12 ETO18704.1 - 5 5.8 5.3 5.4 5.7 3.7 1.0 1 0 0 1 1 1 0 Presenilin DUF3464 PF11947.3 ETO18704.1 - 5.3 6.4 8.6 6.7 6.1 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Folate_carrier PF01770.13 ETO18704.1 - 9.7 4.5 6.3 12 4.2 4.3 1.1 1 0 0 1 1 1 0 Reduced folate carrier NPR3 PF03666.8 ETO18704.1 - 10 4.5 11.8 11 4.3 8.2 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Baculo_PEP_C PF04513.7 ETO18706.1 - 1 9.2 7.3 0.087 12.6 1.0 2.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ribosomal_L36 PF00444.13 ETO18706.1 - 2.1 8.4 8.3 2.5 8.1 4.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L36 DUF2924 PF11149.3 ETO18708.1 - 0.074 13.0 0.4 7.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2924) SPT16 PF08644.6 ETO18708.1 - 0.24 11.2 4.9 0.064 13.0 0.5 1.8 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) SpecificRecomb PF10136.4 ETO18709.1 - 0.049 11.6 0.4 0.065 11.2 0.3 1.1 1 0 0 1 1 1 0 Site-specific recombinase DUF2681 PF10883.3 ETO18709.1 - 6.1 7.1 10.2 0.45 10.7 1.1 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF2681) Kinesin PF00225.18 ETO18710.1 - 1.9e-39 135.3 0.0 3e-39 134.6 0.0 1.3 1 1 0 1 1 1 1 Kinesin motor domain PI3_PI4_kinase PF00454.22 ETO18711.1 - 1.3e-25 90.2 1.2 5.9e-14 52.1 0.1 3.2 2 1 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase DUF3474 PF11960.3 ETO18713.1 - 0.01 15.8 0.6 0.01 15.8 0.4 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3474) LUC7 PF03194.10 ETO18713.1 - 0.031 13.8 4.6 0.055 13.0 3.2 1.3 1 0 0 1 1 1 0 LUC7 N_terminus Apc15p PF05841.6 ETO18713.1 - 6.9 7.4 13.2 0.18 12.5 1.2 3.1 2 1 1 3 3 3 0 Apc15p protein RasGEF PF00617.14 ETO18714.1 - 1.5e-40 138.9 0.1 1.5e-40 138.9 0.1 2.0 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.15 ETO18714.1 - 4.7e-11 42.7 0.1 4.7e-11 42.7 0.1 2.6 3 0 0 3 3 3 1 RasGEF N-terminal motif Siah-Interact_N PF09032.6 ETO18714.1 - 0.52 10.3 12.3 2.8 8.0 0.8 3.0 2 0 0 2 2 2 0 Siah interacting protein, N terminal Esterase_phd PF10503.4 ETO18715.1 - 0.00052 19.3 0.7 0.0012 18.0 0.3 1.8 2 1 0 2 2 2 1 Esterase PHB depolymerase Lipocalin_7 PF14651.1 ETO18716.1 - 0.0064 16.2 0.7 0.018 14.7 0.5 1.9 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Thaumatin PF00314.12 ETO18717.1 - 2.6e-20 72.7 9.4 5.7e-12 45.5 0.8 5.3 3 2 1 5 5 5 2 Thaumatin family SAP PF02037.22 ETO18718.1 - 2.1e-09 36.6 0.1 7.3e-09 34.9 0.0 2.0 2 0 0 2 2 2 1 SAP domain WGR PF05406.10 ETO18718.1 - 1.9e-06 27.6 0.0 1.9e-06 27.6 0.0 3.0 3 0 0 3 3 3 1 WGR domain Mak16 PF04874.9 ETO18718.1 - 0.0011 19.0 7.7 0.0011 19.0 5.3 3.3 3 0 0 3 3 3 1 Mak16 protein C-terminal region WD40 PF00400.27 ETO18720.1 - 7.5e-29 98.5 5.5 8.3e-14 50.8 0.2 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO18720.1 - 0.00017 20.4 0.0 0.0041 15.9 0.0 2.0 1 1 0 2 2 2 2 Nup133 N terminal like eIF2A PF08662.6 ETO18720.1 - 0.016 14.9 0.0 0.21 11.2 0.0 2.0 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A V-ATPase_G PF03179.10 ETO18721.1 - 1.8e-13 50.6 13.4 2.3e-13 50.3 9.3 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3584 PF12128.3 ETO18721.1 - 0.02 12.2 10.9 0.023 12.0 7.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FRD2 PF03197.8 ETO18721.1 - 0.023 15.2 2.8 0.03 14.8 2.0 1.2 1 0 0 1 1 1 0 Bacteriophage FRD2 protein Filament PF00038.16 ETO18721.1 - 0.029 13.8 10.8 0.034 13.6 7.5 1.1 1 0 0 1 1 1 0 Intermediate filament protein Uds1 PF15456.1 ETO18721.1 - 0.041 13.8 4.9 0.057 13.4 3.4 1.4 1 0 0 1 1 1 0 Up-regulated During Septation DUF781 PF05612.7 ETO18721.1 - 0.069 11.8 0.5 0.08 11.6 0.3 1.1 1 0 0 1 1 1 0 Mouse protein of unknown function (DUF781) DUF3337 PF11816.3 ETO18721.1 - 0.083 12.2 6.5 0.097 12.0 4.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) CmcH_NodU PF02543.10 ETO18721.1 - 0.089 11.9 4.1 0.11 11.6 2.9 1.0 1 0 0 1 1 1 0 Carbamoyltransferase DUF262 PF03235.9 ETO18721.1 - 0.1 12.5 6.3 0.12 12.2 4.3 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF262 EURL PF06937.6 ETO18721.1 - 0.11 11.8 7.5 0.14 11.5 5.2 1.1 1 0 0 1 1 1 0 EURL protein Tropomyosin_1 PF12718.2 ETO18721.1 - 0.15 11.9 19.9 0.22 11.3 13.8 1.3 1 1 0 1 1 1 0 Tropomyosin like GBP_C PF02841.9 ETO18721.1 - 0.18 10.9 10.0 0.19 10.8 6.9 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain LXG PF04740.7 ETO18721.1 - 0.18 11.5 10.3 0.21 11.3 7.1 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily ATP-synt_B PF00430.13 ETO18721.1 - 0.23 11.2 11.9 1.1 9.1 4.1 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Striatin PF08232.7 ETO18721.1 - 0.32 11.3 13.3 0.39 11.0 9.2 1.1 1 0 0 1 1 1 0 Striatin family DUF3552 PF12072.3 ETO18721.1 - 0.35 10.0 19.0 1.7 7.8 13.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) DUF4407 PF14362.1 ETO18721.1 - 0.62 8.9 6.1 0.69 8.8 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6 PF04111.7 ETO18721.1 - 0.64 9.0 10.4 0.74 8.8 7.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4200 PF13863.1 ETO18721.1 - 0.84 9.5 16.3 0.7 9.8 10.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Mnd1 PF03962.10 ETO18721.1 - 0.88 9.2 12.4 1.1 8.8 8.6 1.1 1 0 0 1 1 1 0 Mnd1 family DUF4559 PF15112.1 ETO18721.1 - 0.92 8.6 10.9 1.1 8.3 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Presenilin PF01080.12 ETO18721.1 - 1 8.1 4.9 1.1 7.9 3.4 1.0 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.14 ETO18721.1 - 1 7.1 7.4 1.1 7.0 5.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3373 PF11853.3 ETO18721.1 - 1 7.7 5.5 1.1 7.7 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Bap31 PF05529.7 ETO18721.1 - 1.3 8.4 13.2 1.4 8.3 9.0 1.3 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like OmpH PF03938.9 ETO18721.1 - 1.6 8.6 11.6 2.1 8.2 8.1 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Seryl_tRNA_N PF02403.17 ETO18721.1 - 2.3 8.2 16.5 0.97 9.4 0.7 2.7 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TMPIT PF07851.8 ETO18721.1 - 2.4 7.1 8.9 2.7 6.9 6.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein FAM75 PF14650.1 ETO18721.1 - 2.6 7.3 8.9 3.1 7.1 6.2 1.1 1 0 0 1 1 1 0 FAM75 family Phage_GP20 PF06810.6 ETO18721.1 - 2.6 7.4 20.4 4.2 6.7 3.5 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF4446 PF14584.1 ETO18721.1 - 3.3 7.5 7.3 3.7 7.3 4.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) HSP70 PF00012.15 ETO18721.1 - 3.5 5.4 11.0 3.7 5.3 7.6 1.1 1 0 0 1 1 1 0 Hsp70 protein Laminin_II PF06009.7 ETO18721.1 - 4 7.2 11.5 6.2 6.5 8.0 1.4 1 1 0 1 1 1 0 Laminin Domain II RRF PF01765.14 ETO18721.1 - 4.6 6.6 16.8 2.8 7.3 5.7 2.0 1 1 1 2 2 2 0 Ribosome recycling factor Histone_HNS PF00816.16 ETO18721.1 - 4.9 7.7 9.0 6.6 7.3 5.2 2.0 1 1 2 3 3 3 0 H-NS histone family IncA PF04156.9 ETO18721.1 - 5.1 6.6 10.6 6.2 6.3 7.4 1.2 1 0 0 1 1 1 0 IncA protein Fib_alpha PF08702.5 ETO18721.1 - 9 6.4 12.1 18 5.4 8.4 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family HutD PF05962.6 ETO18722.1 - 8.4e-37 126.6 0.0 9.4e-37 126.5 0.0 1.0 1 0 0 1 1 1 1 HutD Methyltransf_12 PF08242.7 ETO18724.1 - 1.6 9.2 4.1 1.4 9.4 1.7 1.8 1 1 1 2 2 2 0 Methyltransferase domain Exo_endo_phos PF03372.18 ETO18725.1 - 2.7e-06 27.5 0.3 4e-06 26.9 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ycf1 PF05758.7 ETO18726.1 - 0.3 8.7 10.8 0.37 8.4 7.5 1.1 1 0 0 1 1 1 0 Ycf1 Adaptin_binding PF10199.4 ETO18726.1 - 0.62 10.3 23.4 1.4 9.2 16.2 1.6 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Presenilin PF01080.12 ETO18726.1 - 0.63 8.8 8.6 0.85 8.3 6.0 1.3 1 0 0 1 1 1 0 Presenilin Daxx PF03344.10 ETO18726.1 - 2.3 6.5 21.9 3.1 6.1 15.2 1.2 1 0 0 1 1 1 0 Daxx Family Menin PF05053.8 ETO18726.1 - 2.5 6.1 10.4 3 5.9 7.2 1.1 1 0 0 1 1 1 0 Menin DUF1510 PF07423.6 ETO18726.1 - 3.9 6.7 25.4 7.5 5.8 17.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) VPS9 PF02204.13 ETO18729.1 - 1.3e-13 50.8 0.2 1.7e-13 50.4 0.1 1.2 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain TraO PF10626.4 ETO18729.1 - 0.078 12.3 0.1 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Conjugative transposon protein TraO HEAT_EZ PF13513.1 ETO18730.1 - 1.2e-09 38.3 0.0 0.0021 18.4 0.0 3.3 4 0 0 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.1 ETO18730.1 - 7.1e-09 35.8 0.0 0.00025 21.2 0.0 2.7 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.17 ETO18730.1 - 1.5e-08 34.0 0.0 0.001 18.9 0.0 4.4 4 1 0 4 4 4 2 HEAT repeat Cnd1 PF12717.2 ETO18730.1 - 3.5e-06 26.9 3.8 0.00066 19.5 0.3 2.5 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 ETO18730.1 - 0.00022 21.5 0.8 1.6 9.1 0.0 3.9 2 2 2 4 4 4 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 ETO18730.1 - 0.00023 19.6 1.7 0.088 11.1 0.0 2.2 1 1 1 2 2 2 2 Adaptin N terminal region TIP120 PF08623.5 ETO18730.1 - 0.0033 17.0 2.4 5.2 6.6 0.0 3.4 2 1 1 3 3 3 2 TATA-binding protein interacting (TIP20) DUF3554 PF12074.3 ETO18730.1 - 0.051 13.0 0.2 0.81 9.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3554) Condensin2nSMC PF12422.3 ETO18730.1 - 0.12 12.1 0.2 1 9.0 0.0 2.1 2 1 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit RPT PF13446.1 ETO18730.1 - 0.15 11.5 0.2 0.44 9.9 0.0 1.9 2 0 0 2 2 2 0 A repeated domain in UCH-protein DUF3944 PF13099.1 ETO18730.1 - 1.9 8.0 7.6 7 6.2 0.1 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF3944) KGK PF08872.5 ETO18731.1 - 0.026 14.6 0.6 0.086 12.9 0.1 2.0 2 0 0 2 2 2 0 KGK domain Herpes_UL24 PF01646.11 ETO18734.1 - 0.027 13.9 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 Herpes virus protein UL24 Noelin-1 PF12308.3 ETO18735.1 - 0.06 13.1 0.3 0.097 12.4 0.2 1.4 1 0 0 1 1 1 0 Neurogenesis glycoprotein IF2_assoc PF08364.6 ETO18735.1 - 0.45 10.5 0.1 0.45 10.5 0.0 3.0 4 0 0 4 4 4 0 Bacterial translation initiation factor IF-2 associated region YqfQ PF14181.1 ETO18736.1 - 0.13 12.3 13.7 0.16 12.0 9.5 1.2 1 0 0 1 1 1 0 YqfQ-like protein RR_TM4-6 PF06459.7 ETO18736.1 - 0.13 12.0 10.7 0.14 11.9 7.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Phage_Gp23 PF10669.4 ETO18736.1 - 0.18 11.9 8.8 0.26 11.4 6.1 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Peptidase_U57 PF05582.7 ETO18736.1 - 0.2 10.6 6.9 0.23 10.3 4.8 1.0 1 0 0 1 1 1 0 YabG peptidase U57 AIF_C PF14721.1 ETO18736.1 - 0.28 11.4 5.0 0.33 11.1 3.4 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF1510 PF07423.6 ETO18736.1 - 0.3 10.4 16.2 0.33 10.2 11.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Tom37_C PF11801.3 ETO18736.1 - 0.75 9.6 10.1 0.88 9.4 7.0 1.0 1 0 0 1 1 1 0 Tom37 C-terminal domain GAGA_bind PF06217.7 ETO18736.1 - 0.82 9.5 15.2 0.92 9.4 10.6 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Afi1 PF07792.7 ETO18736.1 - 1.1 9.2 7.1 1.1 9.2 4.9 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Zip PF02535.17 ETO18736.1 - 1.1 8.1 4.0 1.3 7.9 2.8 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter U79_P34 PF03064.11 ETO18736.1 - 1.6 8.2 13.2 1.7 8.1 9.2 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DDHD PF02862.12 ETO18736.1 - 1.6 8.4 9.0 1.8 8.2 6.2 1.0 1 0 0 1 1 1 0 DDHD domain Vfa1 PF08432.5 ETO18736.1 - 1.7 8.6 22.3 2 8.3 15.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Neur_chan_memb PF02932.11 ETO18736.1 - 1.7 8.4 5.6 1.9 8.3 3.9 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Folate_carrier PF01770.13 ETO18736.1 - 2.3 6.6 4.9 2.3 6.6 3.4 1.1 1 0 0 1 1 1 0 Reduced folate carrier Agouti PF05039.7 ETO18736.1 - 2.4 8.5 7.9 3.6 8.0 5.5 1.3 1 0 0 1 1 1 0 Agouti protein EIIBC-GUT_N PF03612.9 ETO18736.1 - 2.4 7.7 7.8 2.7 7.5 5.4 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Tim54 PF11711.3 ETO18736.1 - 3.1 6.3 10.9 3.4 6.1 7.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Ycf1 PF05758.7 ETO18736.1 - 3.2 5.3 12.2 3.4 5.2 8.5 1.0 1 0 0 1 1 1 0 Ycf1 DUF3408 PF11888.3 ETO18736.1 - 3.6 7.5 10.9 4.1 7.3 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) DUF2413 PF10310.4 ETO18736.1 - 3.6 6.2 14.8 4.1 6.1 10.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Glyco_transf_15 PF01793.11 ETO18736.1 - 3.7 6.3 9.4 4 6.2 6.5 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase RNA_pol_Rpb1_5 PF04998.12 ETO18736.1 - 3.8 6.6 7.8 4.1 6.5 5.4 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 RNase_H2-Ydr279 PF09468.5 ETO18736.1 - 3.9 6.5 17.9 4.4 6.4 12.4 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) CDC45 PF02724.9 ETO18736.1 - 4.4 5.2 9.9 4.9 5.0 6.9 1.0 1 0 0 1 1 1 0 CDC45-like protein MIP-T3 PF10243.4 ETO18736.1 - 4.7 5.5 24.4 5.2 5.4 16.9 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Atrophin-1 PF03154.10 ETO18736.1 - 4.7 5.2 8.7 4.9 5.1 6.0 1.0 1 0 0 1 1 1 0 Atrophin-1 family Sec62 PF03839.11 ETO18736.1 - 4.8 6.5 16.3 5 6.4 11.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF3807 PF12720.2 ETO18736.1 - 5 7.2 15.3 5.9 7.0 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Conotoxin PF02950.12 ETO18736.1 - 5.1 7.9 6.5 7.2 7.4 4.5 1.4 1 0 0 1 1 1 0 Conotoxin Borrelia_P83 PF05262.6 ETO18736.1 - 5.2 5.2 18.2 6.3 4.9 12.6 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein GCD14 PF08704.5 ETO18736.1 - 5.6 6.3 6.4 5.9 6.3 4.5 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Paramyxo_ncap PF00973.14 ETO18736.1 - 7.6 5.1 7.1 8.1 5.0 4.9 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Eapp_C PF10238.4 ETO18736.1 - 7.9 6.3 12.2 11 5.9 8.4 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF4337 PF14235.1 ETO18736.1 - 8.2 6.2 7.2 10 5.9 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF3451 PF11933.3 ETO18736.1 - 8.3 6.1 13.8 9.1 5.9 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3451) DUF4604 PF15377.1 ETO18736.1 - 8.4 6.5 24.2 10 6.3 16.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Pox_P35 PF03213.9 ETO18736.1 - 9 5.1 9.2 10 5.0 6.3 1.0 1 0 0 1 1 1 0 Poxvirus P35 protein RNA_pol_Rpc4 PF05132.9 ETO18736.1 - 10 6.1 12.1 14 5.7 8.4 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 MTHFR PF02219.12 ETO18737.1 - 2.4e-62 210.6 0.0 4.6e-57 193.3 0.0 2.2 2 0 0 2 2 2 2 Methylenetetrahydrofolate reductase DUF4512 PF14975.1 ETO18738.1 - 0.016 16.0 0.9 0.06 14.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) WD40 PF00400.27 ETO18739.1 - 1.2e-53 177.1 27.1 5.5e-12 45.0 0.3 6.7 7 2 1 8 8 8 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO18739.1 - 5.8e-10 37.9 6.1 0.078 11.0 0.0 4.9 1 1 4 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO18739.1 - 0.0033 16.2 7.0 1 7.9 0.7 4.0 1 1 2 3 3 3 2 Nup133 N terminal like DUF413 PF04219.7 ETO18740.1 - 0.037 13.7 0.1 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF Dicty_REP PF05086.7 ETO18740.1 - 0.094 10.4 3.6 0.11 10.2 2.5 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein NAD_binding_1 PF00175.16 ETO18740.1 - 0.15 12.6 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain Mucin PF01456.12 ETO18740.1 - 0.17 11.6 19.8 0.3 10.8 13.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Menin PF05053.8 ETO18740.1 - 1.8 6.6 5.0 2.2 6.3 3.5 1.1 1 0 0 1 1 1 0 Menin SSP160 PF06933.6 ETO18740.1 - 2.2 6.1 13.7 2.7 5.8 9.5 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 adh_short_C2 PF13561.1 ETO18741.1 - 0.0067 16.2 0.1 0.013 15.2 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETO18741.1 - 0.012 15.4 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase DUF3439 PF11921.3 ETO18741.1 - 0.015 15.0 7.3 0.026 14.2 5.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 ETO18741.1 - 0.018 14.8 11.4 0.024 14.4 7.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Glyco_tran_WecB PF03808.8 ETO18741.1 - 0.095 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family BSP_II PF05432.6 ETO18741.1 - 0.88 8.7 16.8 1.1 8.4 11.6 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) PGA2 PF07543.7 ETO18742.1 - 0.0027 17.4 1.5 0.0027 17.4 1.1 5.6 4 1 1 5 5 5 1 Protein trafficking PGA2 AAA_18 PF13238.1 ETO18743.1 - 4.4e-07 30.2 0.0 8.7e-07 29.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO18743.1 - 0.00023 21.9 0.0 0.00031 21.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain ADK PF00406.17 ETO18743.1 - 0.001 18.9 0.0 0.028 14.3 0.0 2.1 1 1 0 1 1 1 1 Adenylate kinase AAA_22 PF13401.1 ETO18743.1 - 0.019 15.1 0.0 0.051 13.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 ETO18743.1 - 0.019 14.4 0.0 0.16 11.4 0.0 2.4 2 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 ETO18743.1 - 0.031 14.5 0.0 0.042 14.1 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 ETO18743.1 - 0.039 13.8 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 ETO18743.1 - 0.066 13.3 0.0 0.12 12.5 0.0 1.5 1 1 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.18 ETO18743.1 - 0.13 12.1 0.0 0.21 11.5 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Plasmodium_Vir PF05795.6 ETO18744.1 - 0.035 13.3 0.3 0.038 13.1 0.2 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein LETM1 PF07766.8 ETO18744.1 - 0.073 12.0 0.1 0.085 11.8 0.0 1.1 1 0 0 1 1 1 0 LETM1-like protein DUF506 PF04720.7 ETO18745.1 - 0.68 9.5 5.2 0.66 9.5 3.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Na_H_Exchanger PF00999.16 ETO18746.1 - 1.6e-29 102.6 10.6 1.9e-29 102.4 7.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Claudin_2 PF13903.1 ETO18746.1 - 0.01 15.5 5.1 0.014 15.1 3.5 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction FecCD PF01032.13 ETO18746.1 - 0.34 9.7 8.3 0.028 13.2 2.2 1.8 2 0 0 2 2 2 0 FecCD transport family DUF3021 PF11457.3 ETO18746.1 - 0.88 9.4 7.1 11 5.9 4.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3021) FeoB_C PF07664.7 ETO18746.1 - 5.6 6.4 6.3 0.51 9.8 0.1 2.6 3 1 0 3 3 3 0 Ferrous iron transport protein B C terminus TPR_11 PF13414.1 ETO18747.1 - 9.5e-17 60.4 1.3 2e-13 49.7 0.2 2.5 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETO18747.1 - 3e-13 48.7 8.2 0.0015 18.0 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO18747.1 - 6.2e-12 44.4 4.2 0.0014 18.3 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 ETO18747.1 - 9e-07 28.7 2.1 0.022 14.7 0.0 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat PPP5 PF08321.7 ETO18747.1 - 5.7e-06 26.2 0.6 0.00029 20.7 0.0 3.0 2 1 0 3 3 3 1 PPP5 TPR repeat region TPR_8 PF13181.1 ETO18747.1 - 0.00042 19.9 13.7 0.28 11.0 0.1 5.0 4 1 0 4 4 4 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO18747.1 - 0.12 11.6 0.1 9.6 5.5 0.0 2.6 3 0 0 3 3 3 0 SHNi-TPR TPR_7 PF13176.1 ETO18747.1 - 0.25 11.2 1.1 7.4 6.6 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO18747.1 - 0.28 11.7 5.5 9.2 6.9 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF964 PF06133.6 ETO18747.1 - 2.7 8.0 9.1 5.9 6.9 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF964) CcmD PF04995.9 ETO18749.1 - 0.12 12.0 3.7 12 5.7 0.5 3.2 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) DUF2899 PF11449.3 ETO18749.1 - 1.3 8.1 11.0 0.19 10.9 4.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2899) RGS PF00615.14 ETO18750.1 - 0.0059 16.6 2.0 0.016 15.2 1.4 1.8 1 1 0 1 1 1 1 Regulator of G protein signaling domain GDC-P PF02347.11 ETO18751.1 - 1e-88 297.9 0.3 3.2e-88 296.2 0.0 1.8 2 0 0 2 2 2 1 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 ETO18751.1 - 0.019 14.1 0.1 0.055 12.6 0.0 1.8 2 1 0 2 2 2 0 Beta-eliminating lyase Sigma_reg_C PF13791.1 ETO18751.1 - 0.16 11.9 2.0 0.24 11.4 0.9 1.7 1 1 1 2 2 2 0 Sigma factor regulator C-terminal GDC-P PF02347.11 ETO18752.1 - 5.6e-08 31.8 0.3 1.7e-06 27.0 0.2 2.0 2 0 0 2 2 2 2 Glycine cleavage system P-protein AphA_like PF14557.1 ETO18753.1 - 0.04 13.4 0.8 0.085 12.4 0.6 1.5 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator TMEM223 PF14640.1 ETO18753.1 - 0.071 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 223 Pkinase PF00069.20 ETO18755.1 - 5.1e-58 196.2 0.0 5.9e-58 196.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO18755.1 - 2.4e-37 128.4 0.0 2.8e-37 128.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO18755.1 - 1.4e-08 34.0 0.0 1.7e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETO18755.1 - 0.00012 21.9 0.0 0.00019 21.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 ETO18755.1 - 0.0044 16.0 0.1 0.0078 15.2 0.0 1.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 ETO18755.1 - 0.062 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.6 ETO18755.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 TPR_8 PF13181.1 ETO18756.1 - 0.002 17.8 4.4 0.0021 17.7 0.2 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO18756.1 - 0.063 13.2 3.1 0.58 10.1 0.1 2.2 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETO18756.1 - 0.25 11.3 2.6 10 6.3 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Alpha-amylase PF00128.19 ETO18757.1 - 1.1e-06 28.3 0.0 1.5e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain PK PF00224.16 ETO18758.1 - 2e-133 444.3 11.8 6e-91 304.6 3.0 2.1 1 1 1 2 2 2 2 Pyruvate kinase, barrel domain PK_C PF02887.11 ETO18758.1 - 1.6e-22 79.2 2.4 4.4e-22 77.8 0.0 2.7 3 1 0 3 3 3 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 ETO18758.1 - 8.9e-05 21.4 0.8 0.00025 20.0 0.5 1.8 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family ENTH PF01417.15 ETO18759.1 - 1.4e-11 44.3 0.1 2.1e-11 43.7 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ER PF01133.12 ETO18759.1 - 0.048 13.3 0.5 0.087 12.5 0.3 1.4 1 0 0 1 1 1 0 Enhancer of rudimentary Glyco_tran_WbsX PF14307.1 ETO18759.1 - 0.29 10.2 4.0 0.92 8.6 0.8 2.0 1 1 1 2 2 2 0 Glycosyltransferase WbsX PDEase_I PF00233.14 ETO18760.1 - 2.1e-25 89.8 1.6 3.2e-25 89.2 1.1 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 ETO18760.1 - 0.0039 17.1 0.1 0.0074 16.2 0.0 1.6 2 0 0 2 2 2 1 HD domain DUF2314 PF10077.4 ETO18760.1 - 0.039 14.0 0.0 1.6 8.8 0.0 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2314) PDEase_I PF00233.14 ETO18761.1 - 6.7e-23 81.6 0.0 2.2e-22 79.9 0.0 1.9 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I PF00233.14 ETO18762.1 - 1.5e-61 208.1 0.0 4.8e-61 206.5 0.0 1.7 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 ETO18762.1 - 0.07 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 HD domain Sortase PF04203.8 ETO18764.1 - 0.0052 16.3 0.1 0.009 15.5 0.1 1.4 1 0 0 1 1 1 1 Sortase family Baculo_LEF5_C PF11792.3 ETO18764.1 - 0.073 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain Cadherin PF00028.12 ETO18764.1 - 0.26 11.5 1.4 1.9 8.7 0.1 2.7 1 1 1 2 2 2 0 Cadherin domain ETRAMP PF09716.5 ETO18765.1 - 0.0019 18.1 0.1 0.0082 16.0 0.0 2.0 2 1 0 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) Tubulin PF00091.20 ETO18766.1 - 1.8e-70 237.1 0.0 2.5e-70 236.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO18766.1 - 3.3e-33 114.4 0.1 1.3e-26 93.0 0.1 2.3 1 1 1 2 2 2 2 Tubulin C-terminal domain Tubulin_3 PF14881.1 ETO18766.1 - 0.002 17.5 0.0 0.0033 16.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Cwf_Cwc_15 PF04889.7 ETO18767.1 - 0.0047 16.6 14.5 0.0065 16.2 10.0 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Glyco_transf_15 PF01793.11 ETO18767.1 - 0.057 12.3 3.9 0.064 12.2 2.7 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase PVL_ORF50 PF07768.6 ETO18767.1 - 0.58 10.1 10.1 1.2 9.1 7.0 1.4 1 0 0 1 1 1 0 PVL ORF-50-like family Nucleoplasmin PF03066.10 ETO18767.1 - 1.3 8.4 11.7 4.6 6.7 0.3 2.3 2 0 0 2 2 2 0 Nucleoplasmin FHIPEP PF00771.15 ETO18767.1 - 3.9 5.6 5.6 3 6.0 3.1 1.3 1 1 0 1 1 1 0 FHIPEP family Phage_Gp23 PF10669.4 ETO18767.1 - 6.1 6.9 12.5 1.3 9.1 0.9 2.5 2 1 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DUF912 PF06024.7 ETO18767.1 - 7 6.7 6.2 9.2 6.3 0.4 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PMSI1 PF15322.1 ETO18768.1 - 0.052 12.6 3.2 0.06 12.4 2.2 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Pneumo_phosprot PF02478.11 ETO18768.1 - 0.063 12.8 6.4 0.074 12.5 4.4 1.1 1 0 0 1 1 1 0 Pneumovirus phosphoprotein Secretin_N_2 PF07655.8 ETO18768.1 - 0.067 13.5 20.6 0.13 12.6 14.3 1.6 1 1 0 1 1 1 0 Secretin N-terminal domain CDC14 PF08045.6 ETO18768.1 - 0.14 11.2 6.4 1.7 7.7 2.5 2.5 1 1 1 2 2 2 0 Cell division control protein 14, SIN component RabGAP-TBC PF00566.13 ETO18768.1 - 0.15 11.5 0.1 0.15 11.5 0.0 2.3 2 0 0 2 2 2 0 Rab-GTPase-TBC domain Menin PF05053.8 ETO18768.1 - 1.1 7.4 8.7 1.3 7.0 6.0 1.1 1 0 0 1 1 1 0 Menin AIF_C PF14721.1 ETO18768.1 - 2.5 8.3 6.3 3.7 7.7 4.1 1.5 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FMO-like PF00743.14 ETO18769.1 - 3.7e-19 68.3 0.0 1.6e-17 62.9 0.0 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 ETO18769.1 - 3.4e-16 59.9 0.0 5.6e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETO18769.1 - 7.6e-09 35.7 0.0 1.5e-08 34.7 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETO18769.1 - 3.7e-07 30.0 0.0 7.5e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 ETO18769.1 - 0.00017 20.6 0.0 0.06 12.2 0.0 2.4 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 ETO18769.1 - 0.00018 20.5 0.1 0.0011 17.9 0.0 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETO18769.1 - 0.00018 21.8 0.0 0.022 15.1 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETO18769.1 - 0.018 14.8 0.2 0.24 11.1 0.0 2.1 1 1 1 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 ETO18769.1 - 0.022 13.8 0.1 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.19 ETO18769.1 - 0.05 12.4 0.0 0.088 11.6 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FtsJ PF01728.14 ETO18772.1 - 3.9e-07 30.2 0.4 1.1e-06 28.7 0.0 1.8 1 1 1 2 2 2 1 FtsJ-like methyltransferase Cript PF10235.4 ETO18773.1 - 0.59 10.5 5.9 0.078 13.3 1.1 1.7 2 1 0 2 2 2 0 Microtubule-associated protein CRIPT KIAA1328 PF15369.1 ETO18773.1 - 2.5 7.8 5.6 3.4 7.3 0.5 2.0 1 1 1 2 2 2 0 Uncharacterised protein KIAA1328 Pkinase PF00069.20 ETO18774.1 - 0.00013 21.2 0.0 0.00016 20.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SR-25 PF10500.4 ETO18776.1 - 0.011 15.1 4.0 0.012 15.1 2.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Poty_PP PF08440.5 ETO18776.1 - 0.03 13.3 0.6 0.038 13.0 0.4 1.2 1 0 0 1 1 1 0 Potyviridae polyprotein MSC PF09402.5 ETO18776.1 - 0.03 13.0 1.8 0.037 12.7 1.2 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain R3H-assoc PF13902.1 ETO18776.1 - 0.067 13.1 0.8 0.086 12.7 0.6 1.3 1 0 0 1 1 1 0 R3H-associated N-terminal domain Folliculin PF11704.3 ETO18776.1 - 0.082 12.4 1.9 0.14 11.7 1.3 1.3 1 1 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Pkinase PF00069.20 ETO18777.1 - 1.3e-41 142.5 0.1 1.9e-41 141.9 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO18777.1 - 3e-28 98.5 0.0 3.9e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO18777.1 - 3.9e-06 26.0 0.0 4.8e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kelch_6 PF13964.1 ETO18778.1 - 3.8e-05 23.6 3.5 0.022 14.8 0.1 4.6 5 0 0 5 5 5 1 Kelch motif Anillin PF08174.6 ETO18778.1 - 0.073 13.1 0.2 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 Cell division protein anillin Kelch_1 PF01344.20 ETO18778.1 - 0.094 12.2 7.5 10 5.7 0.0 3.9 4 1 0 4 4 4 0 Kelch motif CDC45 PF02724.9 ETO18780.1 - 0.0025 15.9 2.4 0.0023 16.0 1.7 1.1 1 0 0 1 1 1 1 CDC45-like protein Atrophin-1 PF03154.10 ETO18780.1 - 0.0043 15.2 1.1 0.0052 15.0 0.8 1.1 1 0 0 1 1 1 1 Atrophin-1 family SDA1 PF05285.7 ETO18780.1 - 0.0081 15.4 7.5 0.0081 15.4 5.2 1.4 2 0 0 2 2 2 1 SDA1 Prog_receptor PF02161.10 ETO18780.1 - 0.015 14.1 5.5 0.021 13.6 3.8 1.1 1 0 0 1 1 1 0 Progesterone receptor Usp PF00582.21 ETO18780.1 - 0.017 15.2 2.1 0.031 14.4 1.4 1.4 1 0 0 1 1 1 0 Universal stress protein family RRN3 PF05327.6 ETO18780.1 - 0.019 13.1 2.6 0.022 12.9 1.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ycf1 PF05758.7 ETO18780.1 - 0.024 12.3 0.8 0.022 12.5 0.6 1.0 1 0 0 1 1 1 0 Ycf1 Radial_spoke PF04712.7 ETO18780.1 - 0.041 12.6 6.6 0.052 12.2 4.6 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein XAP5 PF04921.9 ETO18780.1 - 0.069 12.7 6.7 0.099 12.1 4.7 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator YqfQ PF14181.1 ETO18780.1 - 0.13 12.2 7.0 0.21 11.6 4.8 1.3 1 0 0 1 1 1 0 YqfQ-like protein Sec62 PF03839.11 ETO18780.1 - 0.21 11.0 2.2 0.27 10.6 1.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Tim54 PF11711.3 ETO18780.1 - 0.34 9.4 4.8 0.43 9.1 3.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 ERF PF04404.7 ETO18780.1 - 0.53 9.8 8.9 0.52 9.8 4.5 1.9 2 0 0 2 2 2 0 ERF superfamily S_layer_C PF05124.7 ETO18780.1 - 0.71 9.4 4.8 1.3 8.5 3.3 1.4 1 0 0 1 1 1 0 S-layer like family, C-terminal region GOLD_2 PF13897.1 ETO18780.1 - 0.91 9.7 5.9 0.55 10.4 2.4 1.7 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking TRAP_alpha PF03896.11 ETO18780.1 - 1.1 8.2 9.7 1.8 7.5 6.7 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FAM176 PF14851.1 ETO18780.1 - 1.4 8.6 9.6 0.36 10.5 4.1 1.8 2 0 0 2 2 2 0 FAM176 family VID27 PF08553.5 ETO18780.1 - 2.8 6.0 9.9 4.3 5.4 6.8 1.3 1 0 0 1 1 1 0 VID27 cytoplasmic protein Daxx PF03344.10 ETO18780.1 - 3 6.2 17.6 4.5 5.6 12.2 1.2 1 0 0 1 1 1 0 Daxx Family HSP90 PF00183.13 ETO18780.1 - 3.2 6.0 13.3 4.9 5.4 9.2 1.2 1 0 0 1 1 1 0 Hsp90 protein Dynamin_N PF00350.18 ETO18780.1 - 7.4 6.3 6.8 9.5 6.0 4.3 1.4 1 1 0 1 1 1 0 Dynamin family PBP_sp32 PF07222.7 ETO18780.1 - 7.5 5.6 12.6 14 4.7 8.8 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CobT PF06213.7 ETO18780.1 - 7.8 5.5 14.8 14 4.7 10.3 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF3537 PF12056.3 ETO18780.1 - 8.5 4.9 5.5 7.6 5.1 3.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3537) ANAPC15 PF15243.1 ETO18781.1 - 0.11 12.5 11.3 0.12 12.4 7.9 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 DUF2457 PF10446.4 ETO18781.1 - 0.74 8.4 10.5 0.75 8.4 7.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF4637 PF15470.1 ETO18781.1 - 1.5 8.4 8.9 1.5 8.4 6.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) NOA36 PF06524.7 ETO18781.1 - 1.7 7.8 6.7 1.7 7.8 4.6 1.1 1 0 0 1 1 1 0 NOA36 protein Mis14 PF08641.7 ETO18781.1 - 2.1 8.3 6.2 2.1 8.4 4.3 1.0 1 0 0 1 1 1 0 Kinetochore protein Mis14 like Vfa1 PF08432.5 ETO18781.1 - 2.7 7.9 9.6 2.6 8.0 6.7 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FAM176 PF14851.1 ETO18781.1 - 3.3 7.3 7.0 3.6 7.2 4.8 1.1 1 0 0 1 1 1 0 FAM176 family Pox_Ag35 PF03286.9 ETO18781.1 - 4.1 6.8 10.3 4.4 6.7 7.1 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Paf1 PF03985.8 ETO18781.1 - 4.8 5.8 10.6 4.7 5.8 7.4 1.0 1 0 0 1 1 1 0 Paf1 RXT2_N PF08595.6 ETO18781.1 - 4.9 6.9 6.4 5 6.9 4.4 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 ETO18781.1 - 4.9 6.6 11.1 5.2 6.5 7.7 1.1 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 ETO18781.1 - 5.3 7.3 9.5 6 7.1 6.6 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CobT PF06213.7 ETO18781.1 - 5.4 6.0 11.3 6 5.9 7.9 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Rhabdo_ncap PF00945.13 ETO18781.1 - 5.8 5.3 6.0 5.7 5.4 4.2 1.0 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein HSP90 PF00183.13 ETO18781.1 - 7.8 4.7 11.5 7.8 4.7 8.0 1.0 1 0 0 1 1 1 0 Hsp90 protein eIF-3c_N PF05470.7 ETO18781.1 - 8.7 4.2 7.3 8 4.4 5.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus TRAP_alpha PF03896.11 ETO18781.1 - 9 5.1 7.9 8.9 5.2 5.5 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Shisa PF13908.1 ETO18782.1 - 0.001 19.3 0.8 0.0024 18.0 0.1 1.8 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator HMA PF00403.21 ETO18782.1 - 0.0044 17.1 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 Heavy-metal-associated domain TraT PF05818.7 ETO18782.1 - 0.052 12.9 0.0 0.052 12.9 0.0 1.8 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein Mu-like_Pro PF10123.4 ETO18782.1 - 0.071 12.5 1.5 0.097 12.1 1.0 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein Kin17_mid PF10357.4 ETO18782.1 - 0.77 9.4 6.5 7.9 6.1 0.1 2.3 2 0 0 2 2 2 0 Domain of Kin17 curved DNA-binding protein DUF4228 PF14009.1 ETO18782.1 - 1.2 9.1 8.2 2.4 8.2 5.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) ABC_tran PF00005.22 ETO18783.1 - 4.1e-23 82.1 0.0 8.1e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 ETO18783.1 - 2.8e-07 30.2 1.6 6.2e-07 29.1 0.1 1.9 2 0 0 2 2 2 1 ABC transporter transmembrane region AAA_29 PF13555.1 ETO18783.1 - 0.087 12.3 0.0 0.27 10.7 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_21 PF13304.1 ETO18783.1 - 7.1 6.5 19.2 0.031 14.2 4.2 3.1 3 1 0 3 3 3 0 AAA domain MFS_1 PF07690.11 ETO18784.1 - 5e-05 22.1 17.9 5e-05 22.1 12.4 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Cation_efflux PF01545.16 ETO18784.1 - 0.92 8.5 8.2 0.57 9.1 4.4 1.6 2 0 0 2 2 2 0 Cation efflux family Hexapep PF00132.19 ETO18785.1 - 1.5e-06 27.4 9.3 1.2e-05 24.6 1.5 2.5 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) RRM_1 PF00076.17 ETO18785.1 - 6.5e-05 22.4 0.0 0.00013 21.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO18785.1 - 0.0022 17.9 0.1 0.0039 17.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO18785.1 - 0.0056 16.5 0.0 0.0098 15.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MspA PF09203.6 ETO18785.1 - 0.0077 15.6 0.1 0.0077 15.6 0.1 2.1 3 0 0 3 3 3 1 MspA Hexapep_2 PF14602.1 ETO18785.1 - 0.6 9.7 12.8 0.85 9.2 2.4 2.4 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase TilS_C PF11734.3 ETO18787.1 - 0.024 13.8 0.0 0.05 12.8 0.0 1.5 1 0 0 1 1 1 0 TilS substrate C-terminal domain SPX PF03105.14 ETO18787.1 - 0.96 9.1 9.1 3.5 7.3 3.8 2.0 2 0 0 2 2 2 0 SPX domain ATG27 PF09451.5 ETO18787.1 - 1.8 7.7 8.7 2.6 7.1 5.9 1.4 1 1 0 1 1 1 0 Autophagy-related protein 27 HIT PF01230.18 ETO18789.1 - 4.4e-09 36.7 0.0 7.8e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 ETO18789.1 - 0.00011 22.3 0.0 0.00024 21.3 0.0 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Cu_bind_like PF02298.12 ETO18789.1 - 0.025 14.3 0.8 0.1 12.3 0.7 1.9 2 0 0 2 2 2 0 Plastocyanin-like domain WD40 PF00400.27 ETO18790.1 - 7.9e-53 174.5 33.1 6.1e-10 38.6 0.1 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO18790.1 - 5.4e-06 24.8 6.2 0.052 11.6 0.1 4.3 2 2 2 5 5 5 3 Nucleoporin Nup120/160 ADP_ribosyl_GH PF03747.9 ETO18791.1 - 7.1e-32 111.3 0.0 1.3e-31 110.4 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase MUG2_C PF08593.5 ETO18791.1 - 0.27 11.4 2.0 27 5.0 0.2 3.1 3 0 0 3 3 3 0 Meiotically up-regulated glycoproteins C-terminal DUF4407 PF14362.1 ETO18791.1 - 5.7 5.8 17.0 12 4.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Peptidase_S10 PF00450.17 ETO18792.1 - 4.7e-36 124.8 0.5 2.5e-26 92.7 0.0 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase ETRAMP PF09716.5 ETO18795.1 - 9.1 6.3 9.8 66 3.5 4.2 3.8 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Pkinase PF00069.20 ETO18796.1 - 1.9e-25 89.5 0.1 3.6e-25 88.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO18796.1 - 8e-11 41.4 0.0 2.2e-10 40.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase DUF1759 PF03564.10 ETO18796.1 - 0.086 12.6 0.5 0.36 10.6 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1759) ResIII PF04851.10 ETO18797.1 - 0.069 12.9 3.6 0.082 12.7 2.5 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Cas_Cmr5 PF09701.5 ETO18797.1 - 0.5 10.5 6.5 0.65 10.1 4.5 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr5) Nipped-B_C PF12830.2 ETO18797.1 - 1.4 8.5 4.9 1.6 8.3 3.4 1.1 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus Rogdi_lz PF10259.4 ETO18798.1 - 0.004 16.3 0.5 0.0044 16.1 0.3 1.1 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein PRELI PF04707.9 ETO18798.1 - 0.021 14.3 3.2 0.079 12.5 0.7 2.1 1 1 1 2 2 2 0 PRELI-like family DUF2996 PF11210.3 ETO18798.1 - 0.048 13.9 1.6 0.28 11.4 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2996) CCDC84 PF14968.1 ETO18798.1 - 0.069 12.6 0.8 0.078 12.4 0.6 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 RPEL PF02755.10 ETO18798.1 - 0.23 10.8 6.3 4.4 6.7 1.2 2.8 2 0 0 2 2 2 0 RPEL repeat ABC_tran PF00005.22 ETO18800.1 - 2.4e-12 47.3 0.0 5.9e-12 46.0 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 ETO18800.1 - 0.00037 20.5 0.0 0.00069 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 ETO18800.1 - 0.00085 19.1 0.2 0.012 15.4 0.1 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 ETO18800.1 - 0.029 13.6 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain gpUL132 PF11359.3 ETO18801.1 - 0.056 12.7 1.1 1.1 8.5 0.1 2.1 1 1 1 2 2 2 0 Glycoprotein UL132 RIC1 PF07064.8 ETO18802.1 - 2.2e-15 56.8 2.5 2.5e-14 53.3 0.1 3.0 3 0 0 3 3 3 1 RIC1 PP2C PF00481.16 ETO18803.1 - 2.4e-23 82.8 0.0 5.1e-23 81.7 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 ETO18803.1 - 0.0042 16.7 0.0 0.77 9.4 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 ETO18803.1 - 0.1 11.9 0.1 0.57 9.5 0.0 1.9 1 1 0 1 1 1 0 Protein phosphatase 2C CD52 PF15116.1 ETO18803.1 - 1.7 8.5 5.8 5.7 6.8 4.0 2.0 1 0 0 1 1 1 0 CAMPATH-1 antigen Pkinase PF00069.20 ETO18804.1 - 3e-58 196.9 0.2 2.7e-57 193.8 0.2 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO18804.1 - 2.8e-32 111.8 0.1 2.6e-25 88.9 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 ETO18804.1 - 0.003 17.3 0.5 0.014 15.1 0.3 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 ETO18804.1 - 0.0064 15.5 0.0 0.014 14.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 ETO18804.1 - 0.011 15.0 0.0 0.031 13.6 0.0 1.7 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.1 ETO18804.1 - 0.057 12.3 0.1 0.3 9.9 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Daxx PF03344.10 ETO18805.1 - 0.012 14.1 30.4 0.015 13.8 21.1 1.0 1 0 0 1 1 1 0 Daxx Family XPG_N PF00752.12 ETO18806.1 - 0.12 12.6 0.2 0.29 11.4 0.1 1.6 1 0 0 1 1 1 0 XPG N-terminal domain MIP-T3 PF10243.4 ETO18807.1 - 1.7 7.0 51.2 2.3 6.5 35.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 FAD_binding_3 PF01494.14 ETO18808.1 - 9.2e-12 44.6 0.0 2.5e-07 30.0 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.19 ETO18808.1 - 2.4e-06 26.6 0.1 3.3e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETO18808.1 - 2.4e-06 26.7 0.0 3.3e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 ETO18808.1 - 1.8e-05 23.4 0.2 3.6e-05 22.4 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 ETO18808.1 - 2.3e-05 24.3 0.0 4.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETO18808.1 - 0.00088 19.2 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETO18808.1 - 0.0067 16.8 0.0 0.017 15.5 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase C5-epim_C PF06662.8 ETO18808.1 - 0.008 15.4 0.2 0.069 12.4 0.1 2.2 2 0 0 2 2 2 1 D-glucuronyl C5-epimerase C-terminus Pyr_redox_3 PF13738.1 ETO18808.1 - 0.013 15.5 0.0 0.037 14.0 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AMOP PF03782.12 ETO18808.1 - 0.044 13.7 0.7 0.082 12.8 0.5 1.6 1 0 0 1 1 1 0 AMOP domain Lycopene_cycl PF05834.7 ETO18808.1 - 0.051 12.4 0.0 0.088 11.7 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.2 ETO18808.1 - 0.088 11.8 0.0 0.18 10.8 0.0 1.5 1 1 1 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 ETO18808.1 - 0.12 11.1 0.2 0.22 10.3 0.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A SR-25 PF10500.4 ETO18808.1 - 0.17 11.3 5.8 0.33 10.3 4.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2796 PF10986.3 ETO18809.1 - 0.0041 17.1 0.0 0.017 15.1 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2796) DUF1699 PF08004.6 ETO18809.1 - 0.019 14.5 0.6 1.7 8.1 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1699) PA28_beta PF02252.13 ETO18811.1 - 2.5e-34 117.9 1.0 3.7e-34 117.3 0.3 1.6 2 0 0 2 2 2 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.13 ETO18811.1 - 0.0024 18.0 1.2 0.012 15.7 0.1 2.6 3 0 0 3 3 3 1 Proteasome activator pa28 alpha subunit RE_Alw26IDE PF09665.5 ETO18811.1 - 0.18 10.4 7.7 0.3 9.7 5.4 1.3 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) DUF1759 PF03564.10 ETO18811.1 - 1.5 8.6 10.3 0.2 11.4 0.9 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1759) Phytoreo_S7 PF07236.6 ETO18812.1 - 0.048 11.9 0.2 0.072 11.4 0.1 1.2 1 0 0 1 1 1 0 Phytoreovirus S7 protein PQQ_3 PF13570.1 ETO18813.1 - 0.00054 20.1 0.9 0.28 11.5 0.0 3.8 4 0 0 4 4 4 2 PQQ-like domain Vps8 PF12816.2 ETO18817.1 - 1.4e-15 57.0 5.1 2.2e-14 53.1 1.5 3.3 2 1 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 PBP_sp32 PF07222.7 ETO18817.1 - 3.3 6.8 6.6 5.1 6.1 4.6 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Annexin PF00191.15 ETO18818.1 - 9.6e-10 38.2 0.6 3.6e-09 36.3 0.0 2.2 2 0 0 2 2 2 1 Annexin NESP55 PF06390.7 ETO18818.1 - 0.02 14.2 7.9 0.033 13.5 5.5 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Jacalin PF01419.12 ETO18818.1 - 0.03 14.2 1.7 0.17 11.7 1.5 1.9 2 0 0 2 2 2 0 Jacalin-like lectin domain BPL_N PF09825.4 ETO18818.1 - 0.17 10.6 2.9 0.25 10.1 2.0 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal KIAA1328 PF15369.1 ETO18818.1 - 0.67 9.7 4.4 0.92 9.2 3.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 zf-AN1 PF01428.11 ETO18819.1 - 2.4e-06 27.2 0.3 2.4e-06 27.2 0.2 2.8 3 0 0 3 3 3 1 AN1-like Zinc finger Pox_A28 PF04584.9 ETO18819.1 - 6.3 6.6 12.7 1.2 8.9 3.8 2.6 1 1 2 3 3 3 0 Poxvirus A28 family Plasmodium_HRP PF05403.6 ETO18821.1 - 0.0011 18.6 0.0 0.077 12.5 0.0 2.6 1 1 1 2 2 2 2 Plasmodium histidine-rich protein (HRPII/III) MMS1_N PF10433.4 ETO18822.1 - 2.1e-09 36.0 0.9 2.5e-09 35.8 0.6 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CobT PF06213.7 ETO18823.1 - 0.036 13.2 4.3 0.04 13.0 3.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Gcd10p PF04189.8 ETO18823.1 - 0.061 12.4 2.8 0.064 12.3 2.0 1.2 1 0 0 1 1 1 0 Gcd10p family NOA36 PF06524.7 ETO18823.1 - 0.063 12.5 4.7 0.083 12.1 3.2 1.3 1 0 0 1 1 1 0 NOA36 protein Med4 PF10018.4 ETO18823.1 - 0.065 12.6 2.8 0.96 8.8 0.6 2.0 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 ERF PF04404.7 ETO18823.1 - 0.12 11.9 5.5 0.2 11.1 3.8 1.5 1 0 0 1 1 1 0 ERF superfamily Spt5_N PF11942.3 ETO18823.1 - 0.25 11.9 5.1 0.43 11.2 3.5 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF2457 PF10446.4 ETO18823.1 - 0.31 9.7 7.7 0.38 9.4 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) GOLD_2 PF13897.1 ETO18823.1 - 0.64 10.2 2.7 1.3 9.2 1.8 1.4 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking CENP-B_dimeris PF09026.5 ETO18823.1 - 5.2 7.3 8.2 11 6.3 5.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4611 PF15387.1 ETO18823.1 - 8.7 6.5 10.3 30 4.8 7.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) Ank_2 PF12796.2 ETO18824.1 - 6.8e-19 67.9 0.0 1.2e-12 48.0 0.0 3.5 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO18824.1 - 9.7e-16 57.8 0.3 0.00012 22.5 0.0 4.1 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 ETO18824.1 - 1.2e-15 56.3 0.3 2.7e-05 23.7 0.0 5.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.1 ETO18824.1 - 5.9e-15 53.8 0.0 0.0086 16.2 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 ETO18824.1 - 6.3e-14 51.6 1.9 1e-06 28.8 0.1 4.9 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Pkinase PF00069.20 ETO18825.1 - 4.7e-13 48.8 1.2 7.8e-13 48.1 0.8 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO18825.1 - 3.4e-08 32.8 2.0 6.5e-07 28.6 1.4 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.27 ETO18826.1 - 1.3e-34 116.8 10.7 7.1e-12 44.7 0.4 4.5 4 1 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO18826.1 - 9.7e-06 23.9 0.9 0.029 12.5 0.1 2.8 1 1 1 2 2 2 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO18826.1 - 0.018 14.8 3.0 3.9 7.2 0.2 3.9 1 1 2 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 ETO18826.1 - 0.021 13.5 3.7 0.32 9.6 2.6 2.7 1 1 0 1 1 1 0 Nup133 N terminal like D-ser_dehydrat PF14031.1 ETO18827.1 - 0.029 14.5 0.1 0.17 12.0 0.0 2.3 1 1 0 1 1 1 0 Putative serine dehydratase domain Serinc PF03348.10 ETO18827.1 - 0.17 10.5 0.6 0.21 10.2 0.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) BUD22 PF09073.5 ETO18828.1 - 0.24 10.3 18.0 0.28 10.2 12.5 1.1 1 0 0 1 1 1 0 BUD22 DUF2956 PF11169.3 ETO18828.1 - 1.6 8.7 4.7 1.4 8.9 2.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) DUF1777 PF08648.7 ETO18828.1 - 2.4 7.8 13.3 7.5 6.2 9.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) DBR1 PF05011.8 ETO18829.1 - 9.6e-13 48.2 0.0 3.4e-11 43.2 0.0 2.6 1 1 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain YrhC PF14143.1 ETO18830.1 - 0.1 12.5 0.2 0.35 10.8 0.1 1.9 1 0 0 1 1 1 0 YrhC-like protein Nop14 PF04147.7 ETO18832.1 - 3.7e-05 21.8 5.2 4.5e-05 21.5 3.6 1.2 1 0 0 1 1 1 1 Nop14-like family Claudin_3 PF06653.6 ETO18832.1 - 0.0094 15.6 0.1 0.017 14.8 0.1 1.4 1 0 0 1 1 1 1 Tight junction protein, Claudin-like Voldacs PF03517.8 ETO18832.1 - 0.07 12.9 6.4 0.054 13.3 2.8 2.1 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling Pox_Ag35 PF03286.9 ETO18832.1 - 0.072 12.6 10.8 0.17 11.3 7.5 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Sigma70_ner PF04546.8 ETO18832.1 - 0.13 11.8 12.5 0.27 10.8 8.7 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 ETO18832.1 - 0.21 9.5 9.7 0.34 8.9 6.7 1.2 1 0 0 1 1 1 0 CDC45-like protein eIF-3c_N PF05470.7 ETO18832.1 - 0.33 8.9 10.7 0.55 8.2 7.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Tom37_C PF11801.3 ETO18832.1 - 0.37 10.6 6.3 7.9 6.3 3.5 2.3 2 0 0 2 2 2 0 Tom37 C-terminal domain CobT PF06213.7 ETO18832.1 - 0.88 8.6 13.9 1.5 7.9 9.7 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TRAP_alpha PF03896.11 ETO18832.1 - 1.8 7.4 9.0 2.9 6.7 6.2 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit HSP90 PF00183.13 ETO18832.1 - 2.4 6.4 16.8 4 5.7 11.6 1.3 1 0 0 1 1 1 0 Hsp90 protein NOA36 PF06524.7 ETO18832.1 - 3.2 6.9 11.0 5.7 6.0 7.6 1.3 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.6 ETO18832.1 - 4.9 4.8 10.1 6.8 4.4 7.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PBP1_TM PF14812.1 ETO18832.1 - 5.2 7.4 22.2 1.1 9.6 11.6 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal YqfQ PF14181.1 ETO18832.1 - 5.4 7.0 14.8 11 5.9 10.2 1.5 1 0 0 1 1 1 0 YqfQ-like protein DUF1510 PF07423.6 ETO18832.1 - 5.5 6.2 19.2 11 5.2 13.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Dicty_REP PF05086.7 ETO18832.1 - 5.9 4.5 13.9 0.79 7.3 6.4 1.8 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Daxx PF03344.10 ETO18832.1 - 9.6 4.5 19.3 14 3.9 13.4 1.1 1 0 0 1 1 1 0 Daxx Family FAM176 PF14851.1 ETO18832.1 - 9.6 5.8 12.8 2.6 7.7 6.6 1.7 2 0 0 2 2 2 0 FAM176 family DUF2325 PF10087.4 ETO18833.1 - 0.056 13.2 0.1 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) Med3 PF11593.3 ETO18833.1 - 0.16 11.1 7.8 0.22 10.7 5.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SSP160 PF06933.6 ETO18833.1 - 5.2 4.9 15.2 6.7 4.5 10.6 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf-DHHC PF01529.15 ETO18834.1 - 4e-37 127.2 6.9 7.9e-37 126.3 4.8 1.5 1 1 0 1 1 1 1 DHHC palmitoyltransferase DUF508 PF04370.7 ETO18834.1 - 1.1 8.9 6.6 2 8.0 4.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF508) DUF1272 PF06906.6 ETO18834.1 - 1.8 8.4 7.6 5.1 7.0 5.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) SR-25 PF10500.4 ETO18834.1 - 9 5.6 17.0 13 5.2 11.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Kelch_6 PF13964.1 ETO18835.1 - 3.3e-09 36.5 4.4 0.0012 18.8 0.2 4.4 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 ETO18835.1 - 1.7e-07 31.0 1.8 0.001 18.9 0.2 4.3 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO18835.1 - 1.9e-05 24.3 0.6 0.01 15.5 0.0 3.2 3 1 0 3 3 3 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO18835.1 - 5.1e-05 23.3 0.1 0.0063 16.6 0.0 3.0 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO18835.1 - 0.0002 20.8 5.6 0.16 11.5 0.2 3.1 4 0 0 4 4 4 2 Kelch motif TPR_MLP1_2 PF07926.7 ETO18835.1 - 0.00095 18.9 0.3 0.0017 18.1 0.2 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Kelch_2 PF07646.10 ETO18835.1 - 0.0061 16.2 3.0 8.9 6.2 0.1 4.4 5 0 0 5 5 5 2 Kelch motif GF_recep_IV PF14843.1 ETO18835.1 - 0.061 12.9 0.6 0.15 11.6 0.2 1.7 2 0 0 2 2 2 0 Growth factor receptor domain IV AHSP PF09236.5 ETO18835.1 - 0.08 13.1 0.5 0.19 11.9 0.3 1.6 1 0 0 1 1 1 0 Alpha-haemoglobin stabilising protein WD40 PF00400.27 ETO18836.1 - 4.1e-63 207.1 5.6 3e-12 45.9 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO18836.1 - 2.8e-10 40.2 0.3 0.00063 19.5 0.0 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO18836.1 - 5.6e-08 31.3 1.3 0.039 12.1 0.0 3.7 2 2 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO18836.1 - 8e-06 24.8 9.5 0.62 8.7 0.2 4.7 1 1 2 3 3 3 3 Nup133 N terminal like Proteasome_A_N PF10584.4 ETO18836.1 - 2.4e-05 23.5 0.5 0.51 9.7 0.0 3.5 3 0 0 3 3 3 2 Proteasome subunit A N-terminal signature PD40 PF07676.7 ETO18836.1 - 0.00016 21.2 1.9 3.9 7.2 0.0 3.7 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO18836.1 - 0.0017 16.7 1.4 2.8 6.1 0.1 2.8 1 1 1 3 3 3 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO18836.1 - 0.0027 17.2 0.8 0.068 12.6 0.2 2.9 1 1 0 2 2 2 1 PQQ-like domain DUF2867 PF11066.3 ETO18836.1 - 0.081 12.6 0.1 0.18 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2867) Tox-PL PF15644.1 ETO18836.1 - 0.092 13.4 0.0 78 4.0 0.0 3.6 4 0 0 4 4 4 0 Papain fold toxin 1 Kelch_6 PF13964.1 ETO18837.1 - 1.8e-08 34.2 3.9 0.01 15.9 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO18837.1 - 0.0024 17.5 1.5 1.4 8.7 0.0 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO18837.1 - 0.53 9.8 5.0 0.47 10.0 0.2 3.0 4 0 0 4 4 4 0 Kelch motif YjcZ PF13990.1 ETO18838.1 - 0.031 13.4 1.0 0.034 13.2 0.7 1.0 1 0 0 1 1 1 0 YjcZ-like protein Dynein_heavy PF03028.10 ETO18838.1 - 0.064 11.2 3.1 0.076 11.0 2.2 1.0 1 0 0 1 1 1 0 Dynein heavy chain and region D6 of dynein motor IL3 PF02059.10 ETO18838.1 - 0.082 12.9 2.6 0.13 12.3 1.8 1.3 1 0 0 1 1 1 0 Interleukin-3 Uds1 PF15456.1 ETO18838.1 - 0.14 12.1 3.1 0.2 11.6 2.2 1.2 1 0 0 1 1 1 0 Up-regulated During Septation Ras PF00071.17 ETO18840.1 - 2.6e-07 30.1 1.5 0.0037 16.6 0.0 3.3 2 1 1 3 3 3 3 Ras family Miro PF08477.8 ETO18840.1 - 0.0023 18.4 2.5 0.018 15.5 0.1 2.8 3 0 0 3 3 3 1 Miro-like protein GTP_EFTU PF00009.22 ETO18840.1 - 0.008 15.6 0.0 0.051 13.0 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SNARE PF05739.14 ETO18843.1 - 1.7e-13 50.0 2.9 1.7e-13 50.0 2.0 3.0 3 0 0 3 3 3 1 SNARE domain MCPsignal PF00015.16 ETO18843.1 - 0.00091 18.8 1.2 0.00091 18.8 0.8 2.2 1 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin PF00804.20 ETO18843.1 - 0.0037 17.3 20.6 0.0083 16.2 3.2 3.1 2 1 0 2 2 2 1 Syntaxin Laminin_II PF06009.7 ETO18843.1 - 0.017 14.8 0.3 0.017 14.8 0.2 3.2 1 1 1 3 3 3 0 Laminin Domain II PMC2NT PF08066.7 ETO18843.1 - 0.054 13.8 0.5 0.054 13.8 0.3 2.6 2 1 0 3 3 3 0 PMC2NT (NUC016) domain FliJ PF02050.11 ETO18843.1 - 0.35 10.9 20.5 0.043 13.8 1.6 3.0 2 1 0 2 2 2 0 Flagellar FliJ protein COG2 PF06148.6 ETO18843.1 - 0.45 10.3 11.6 0.16 11.8 0.3 3.3 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 ETRAMP PF09716.5 ETO18843.1 - 0.48 10.4 0.1 0.48 10.4 0.0 2.6 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Syntaxin_2 PF14523.1 ETO18843.1 - 1.2 9.2 18.3 0.34 10.9 0.3 3.1 2 1 0 2 2 2 0 Syntaxin-like protein DUF912 PF06024.7 ETO18843.1 - 1.4 9.0 4.5 1.4 9.0 0.1 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) WXG100 PF06013.7 ETO18843.1 - 2.4 8.2 12.5 3.7 7.6 1.8 3.6 2 2 1 3 3 3 0 Proteins of 100 residues with WXG Mitofilin PF09731.4 ETO18843.1 - 2.9 6.4 15.1 4.9 5.6 10.5 1.4 1 1 0 1 1 1 0 Mitochondrial inner membrane protein DUF445 PF04286.7 ETO18843.1 - 3.2 7.1 14.2 0.62 9.5 4.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF445) DUF3154 PF11351.3 ETO18843.1 - 4.5 7.0 8.1 0.19 11.5 0.4 2.6 2 1 2 4 4 3 0 Protein of unknown function (DUF3154) DASH_Duo1 PF08651.5 ETO18843.1 - 5.2 6.7 9.1 6.8 6.3 0.4 3.2 2 1 0 3 3 3 0 DASH complex subunit Duo1 Phage_Gp23 PF10669.4 ETO18843.1 - 5.5 7.1 7.8 2.1 8.4 0.1 3.0 1 1 2 3 3 3 0 Protein gp23 (Bacteriophage A118) Mod_r PF07200.8 ETO18843.1 - 8.8 6.2 18.3 0.063 13.1 2.4 2.5 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Ras PF00071.17 ETO18844.1 - 9.4e-10 38.1 0.3 1.3e-09 37.6 0.2 1.2 1 0 0 1 1 1 1 Ras family Arf PF00025.16 ETO18844.1 - 0.0015 17.8 0.2 0.0021 17.3 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO18844.1 - 0.0035 16.7 0.2 0.0051 16.2 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 ETO18844.1 - 0.033 12.9 0.0 0.039 12.7 0.0 1.1 1 0 0 1 1 1 0 ArgK protein DUF3377 PF11857.3 ETO18845.1 - 0.03 13.9 0.6 0.37 10.4 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3377) RGS PF00615.14 ETO18845.1 - 0.072 13.2 3.1 1.1 9.3 0.2 2.7 2 0 0 2 2 2 0 Regulator of G protein signaling domain Senescence_reg PF04520.8 ETO18846.1 - 0.012 16.0 1.5 0.012 16.0 1.0 1.8 2 0 0 2 2 2 0 Senescence regulator MSP1_C PF07462.6 ETO18846.1 - 0.02 13.3 6.5 0.029 12.7 4.5 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus SR-25 PF10500.4 ETO18846.1 - 0.038 13.4 13.5 0.06 12.8 9.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Dicty_REP PF05086.7 ETO18846.1 - 0.64 7.7 10.3 0.84 7.3 7.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ATP-synt_D PF01813.12 ETO18847.1 - 0.0091 15.5 8.4 0.0091 15.5 5.8 2.2 1 1 0 2 2 2 1 ATP synthase subunit D DUF664 PF04978.7 ETO18847.1 - 0.011 16.0 1.2 0.011 16.0 0.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF664) APG6 PF04111.7 ETO18847.1 - 0.36 9.8 26.8 0.33 9.9 17.7 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF4248 PF14053.1 ETO18847.1 - 0.55 9.8 4.2 3 7.4 1.4 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4248) Med15 PF09606.5 ETO18847.1 - 1.1 7.4 26.3 1.3 7.1 18.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal V_ATPase_I PF01496.14 ETO18847.1 - 5.9 4.6 17.2 7.1 4.3 11.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PI3K_1B_p101 PF10486.4 ETO18848.1 - 0.12 9.9 3.3 0.14 9.7 2.3 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DDHD PF02862.12 ETO18848.1 - 0.77 9.5 9.5 1.1 8.9 6.6 1.3 1 0 0 1 1 1 0 DDHD domain alpha-hel2 PF14456.1 ETO18848.1 - 0.96 8.1 5.5 1.5 7.5 3.8 1.3 1 0 0 1 1 1 0 Alpha-helical domain 2 Nop14 PF04147.7 ETO18848.1 - 4.6 5.0 22.5 5.3 4.8 15.6 1.2 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.20 ETO18849.1 - 0.0024 17.0 0.0 0.0037 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 ETO18850.1 - 8e-09 35.0 0.2 2.6e-08 33.4 0.1 2.0 1 0 0 1 1 1 1 WD domain, G-beta repeat DHC_N1 PF08385.7 ETO18852.1 - 6.9e-83 278.9 20.2 1e-67 228.8 9.7 3.2 3 0 0 3 3 3 2 Dynein heavy chain, N-terminal region 1 WD40 PF00400.27 ETO18853.1 - 3e-53 175.8 10.9 3.5e-13 48.8 0.1 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO18853.1 - 8.6e-07 27.4 1.0 0.0061 14.7 0.3 2.8 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO18853.1 - 4.6e-06 26.2 0.0 0.03 13.7 0.0 2.3 1 1 1 2 2 2 2 PQQ-like domain eIF2A PF08662.6 ETO18853.1 - 5.4e-06 26.2 0.1 0.013 15.1 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO18853.1 - 0.003 15.9 0.8 0.98 7.6 0.0 2.5 1 1 2 3 3 3 3 Cytochrome D1 heme domain DUF3137 PF11335.3 ETO18853.1 - 0.025 14.2 0.9 0.044 13.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3137) DUF912 PF06024.7 ETO18854.1 - 0.051 13.6 0.1 0.051 13.6 0.1 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1943 PF09172.6 ETO18856.1 - 0.0041 16.0 0.7 0.008 15.0 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) PCNA_C PF02747.10 ETO18856.1 - 0.05 13.5 0.3 0.081 12.8 0.2 1.4 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, C-terminal domain DUF3595 PF12166.3 ETO18856.1 - 0.21 10.3 8.1 0.31 9.8 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) Ion_trans PF00520.26 ETO18858.1 - 8.4e-36 123.1 33.4 6.1e-28 97.4 5.5 2.5 3 0 0 3 3 3 2 Ion transport protein PKD_channel PF08016.7 ETO18858.1 - 3.8e-05 22.2 11.5 9.8e-05 20.9 2.3 3.8 2 2 2 4 4 4 2 Polycystin cation channel DUF983 PF06170.7 ETO18858.1 - 0.033 14.2 1.2 0.17 12.0 0.8 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF983) Ion_trans PF00520.26 ETO18859.1 - 2.6e-13 49.6 0.4 3.6e-13 49.2 0.3 1.2 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.7 ETO18859.1 - 0.0085 14.5 0.1 0.011 14.1 0.1 1.2 1 0 0 1 1 1 1 Polycystin cation channel WD40 PF00400.27 ETO18860.1 - 9.9e-70 228.1 9.9 5.2e-13 48.3 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO18860.1 - 9e-15 54.8 0.6 2.3e-06 27.4 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO18860.1 - 1e-07 30.4 5.4 0.095 10.8 0.0 4.7 2 2 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO18860.1 - 0.00043 19.1 3.4 9.2 4.8 0.1 5.0 1 1 4 5 5 5 2 Nup133 N terminal like PD40 PF07676.7 ETO18860.1 - 0.0011 18.5 6.1 4.1 7.1 0.0 5.7 6 1 1 7 7 7 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 ETO18860.1 - 0.0018 17.4 0.2 0.24 10.4 0.0 3.2 2 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 ETO18860.1 - 0.002 17.4 6.8 9.4 5.6 0.0 5.9 7 0 0 7 7 7 1 Proteasome subunit A N-terminal signature Cytochrom_D1 PF02239.11 ETO18860.1 - 0.067 11.4 0.1 1.4 7.1 0.0 2.7 1 1 2 3 3 3 0 Cytochrome D1 heme domain Kelch_6 PF13964.1 ETO18861.1 - 8e-11 41.6 1.8 3.5e-05 23.7 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO18861.1 - 1.9e-06 27.5 0.6 0.00051 19.7 0.0 3.4 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO18861.1 - 0.0042 17.0 4.9 0.22 11.5 0.2 3.6 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 ETO18861.1 - 0.0092 16.1 0.1 0.13 12.5 0.0 3.0 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO18861.1 - 0.17 11.7 3.6 63 3.5 0.1 4.0 4 0 0 4 4 4 0 Kelch motif Kelch_1 PF01344.20 ETO18861.1 - 0.69 9.5 10.3 8.4 6.0 0.2 4.4 4 1 0 4 4 4 0 Kelch motif WD40 PF00400.27 ETO18862.1 - 8.6e-45 149.0 11.4 2.7e-11 42.8 0.0 8.0 7 1 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO18862.1 - 0.00011 20.5 3.8 1 7.3 0.0 4.0 2 1 2 4 4 4 4 Nucleoporin Nup120/160 CPSF_A PF03178.10 ETO18862.1 - 0.00094 18.3 0.3 0.0015 17.7 0.2 1.3 1 0 0 1 1 1 1 CPSF A subunit region Nucleoporin_N PF08801.6 ETO18862.1 - 0.0087 14.8 10.5 0.72 8.5 2.7 3.6 1 1 1 2 2 2 2 Nup133 N terminal like TPR_12 PF13424.1 ETO18863.1 - 1.1e-69 230.3 8.2 1.1e-20 73.3 0.5 4.8 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.23 ETO18863.1 - 1.7e-36 122.3 30.6 1.9e-08 33.5 1.0 7.5 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETO18863.1 - 2.2e-32 110.5 14.7 4e-14 52.0 0.1 4.5 3 1 0 4 4 4 4 TPR repeat TPR_7 PF13176.1 ETO18863.1 - 2.2e-31 105.1 0.5 7.7e-06 25.3 0.0 5.8 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.1 ETO18863.1 - 7.7e-30 100.4 28.3 2.9e-08 32.9 1.0 7.1 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETO18863.1 - 7.7e-29 97.2 15.5 8.7e-07 28.3 0.3 7.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETO18863.1 - 3.1e-23 80.9 0.0 1.7e-05 24.5 0.0 5.6 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_17 PF13431.1 ETO18863.1 - 2.5e-13 49.0 11.2 0.13 12.5 0.4 6.2 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_6 PF13174.1 ETO18863.1 - 5.8e-12 45.2 4.1 0.22 12.0 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO18863.1 - 9.9e-11 41.2 0.0 0.51 11.1 0.0 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO18863.1 - 2.1e-08 34.6 0.0 0.059 14.0 0.0 3.9 3 1 2 5 5 5 3 Tetratricopeptide repeat MIT PF04212.13 ETO18863.1 - 1.6e-07 31.1 10.4 0.014 15.3 0.5 5.0 5 0 0 5 5 5 2 MIT (microtubule interacting and transport) domain TPR_19 PF14559.1 ETO18863.1 - 9.7e-07 29.0 0.5 0.018 15.3 0.1 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO18863.1 - 2.8e-06 26.4 1.0 0.017 14.3 0.0 4.6 6 0 0 6 6 6 2 SHNi-TPR Apc3 PF12895.2 ETO18863.1 - 1.1e-05 25.4 14.1 0.14 12.3 1.8 4.1 1 1 3 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 PSII_BNR PF14870.1 ETO18863.1 - 0.017 14.1 0.1 0.036 13.0 0.0 1.5 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 Glyco_hyd_65N_2 PF14498.1 ETO18863.1 - 0.018 14.7 0.2 2.3 7.8 0.1 3.0 2 1 1 3 3 3 0 Glycosyl hydrolase family 65, N-terminal domain TPR_5 PF12688.2 ETO18863.1 - 0.049 13.6 0.0 0.72 9.9 0.0 2.7 3 0 0 3 3 3 0 Tetratrico peptide repeat Sel1 PF08238.7 ETO18863.1 - 0.083 13.5 8.5 6.8 7.4 0.3 4.4 5 0 0 5 5 4 0 Sel1 repeat TPR_3 PF07720.7 ETO18863.1 - 0.24 11.2 14.6 0.39 10.5 0.5 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1680 PF07944.7 ETO18864.1 - 0.074 11.3 0.0 0.12 10.6 0.0 1.2 1 0 0 1 1 1 0 Putative glycosyl hydrolase of unknown function (DUF1680) SR-25 PF10500.4 ETO18864.1 - 3.4 7.0 10.9 6.5 6.1 7.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4365 PF14280.1 ETO18865.1 - 0.1 12.3 0.1 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4365) MIP-T3 PF10243.4 ETO18866.1 - 0.00099 17.6 11.5 0.001 17.6 7.9 1.0 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CDC45 PF02724.9 ETO18866.1 - 0.0047 15.0 11.1 0.0047 15.0 7.7 1.0 1 0 0 1 1 1 1 CDC45-like protein TFIIF_alpha PF05793.7 ETO18866.1 - 0.005 15.2 18.5 0.0051 15.2 12.8 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Merozoite_SPAM PF07133.6 ETO18866.1 - 0.011 15.6 23.4 0.016 15.0 16.3 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SDA1 PF05285.7 ETO18866.1 - 0.018 14.3 14.7 0.019 14.2 10.2 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 ETO18866.1 - 0.037 11.9 15.0 0.036 11.9 10.4 1.0 1 0 0 1 1 1 0 Nop14-like family Trypan_glycop_C PF10659.4 ETO18866.1 - 0.056 13.7 8.7 0.075 13.3 6.0 1.2 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain RR_TM4-6 PF06459.7 ETO18866.1 - 0.066 13.1 9.2 0.066 13.1 6.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Daxx PF03344.10 ETO18866.1 - 0.076 11.4 16.5 0.084 11.3 11.4 1.0 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 ETO18866.1 - 0.08 12.3 15.1 0.094 12.0 10.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RNase_H2-Ydr279 PF09468.5 ETO18866.1 - 0.088 11.9 5.2 0.1 11.7 3.6 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) CPSF100_C PF13299.1 ETO18866.1 - 0.088 12.9 4.4 0.11 12.7 3.0 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TLP-20 PF06088.6 ETO18866.1 - 0.1 12.2 6.2 0.14 11.8 4.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) RNA_polI_A34 PF08208.6 ETO18866.1 - 0.16 11.6 18.1 0.2 11.2 12.6 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Myc_N PF01056.13 ETO18866.1 - 0.22 10.6 9.6 0.25 10.4 6.6 1.1 1 0 0 1 1 1 0 Myc amino-terminal region NARP1 PF12569.3 ETO18866.1 - 0.28 9.9 10.0 0.31 9.7 6.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 APG6 PF04111.7 ETO18866.1 - 0.59 9.1 10.2 0.6 9.0 7.1 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Sporozoite_P67 PF05642.6 ETO18866.1 - 1.3 6.7 6.4 1.3 6.8 4.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF809 PF05663.6 ETO18866.1 - 1.5 8.6 7.7 2.2 8.1 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF809) HSP90 PF00183.13 ETO18866.1 - 2.1 6.6 17.5 2.5 6.4 12.1 1.0 1 0 0 1 1 1 0 Hsp90 protein Pox_Ag35 PF03286.9 ETO18866.1 - 2.6 7.5 15.5 3.3 7.1 10.8 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Ycf1 PF05758.7 ETO18866.1 - 2.6 5.6 12.4 2.8 5.5 8.6 1.0 1 0 0 1 1 1 0 Ycf1 DUF3682 PF12446.3 ETO18866.1 - 2.9 8.2 19.4 4.3 7.6 13.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) RRN3 PF05327.6 ETO18866.1 - 3.3 5.7 9.0 3.8 5.5 6.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Vfa1 PF08432.5 ETO18866.1 - 4 7.4 16.8 4.8 7.1 11.6 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TRAP_alpha PF03896.11 ETO18866.1 - 4.5 6.1 10.5 5.4 5.9 7.3 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Zip PF02535.17 ETO18866.1 - 5 6.0 11.1 5.6 5.8 7.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Trypan_PARP PF05887.6 ETO18866.1 - 5.9 6.7 14.9 7.5 6.3 10.3 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Peptidase_S49_N PF08496.5 ETO18866.1 - 6.7 6.4 9.8 7.6 6.3 6.2 1.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal VID27 PF08553.5 ETO18866.1 - 8.2 4.5 16.3 9.6 4.2 11.3 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Abhydrolase_6 PF12697.2 ETO18867.1 - 0.0013 18.6 0.2 0.002 18.0 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pterin_4a PF01329.14 ETO18867.1 - 0.0084 15.8 2.7 0.73 9.6 0.2 2.4 2 0 0 2 2 2 2 Pterin 4 alpha carbinolamine dehydratase Hydrolase_4 PF12146.3 ETO18867.1 - 0.016 15.0 0.1 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase SPX PF03105.14 ETO18867.1 - 0.037 13.8 19.8 0.043 13.5 13.8 1.1 1 0 0 1 1 1 0 SPX domain PPDFL PF15060.1 ETO18867.1 - 3.8 7.5 7.5 1.3 9.0 0.1 2.7 3 0 0 3 3 3 0 Differentiation and proliferation regulator VHS PF00790.14 ETO18868.1 - 3.1e-11 43.0 5.0 1.3e-07 31.3 0.2 2.5 1 1 1 2 2 2 2 VHS domain DUF3461 PF11944.3 ETO18868.1 - 0.043 13.6 2.1 0.07 12.9 0.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3461) GAT PF03127.9 ETO18869.1 - 0.011 15.7 0.2 0.03 14.2 0.0 1.7 1 1 1 2 2 2 0 GAT domain Lyase_1 PF00206.15 ETO18869.1 - 0.054 12.6 0.1 0.067 12.3 0.1 1.1 1 0 0 1 1 1 0 Lyase S6PP PF05116.8 ETO18871.1 - 2.5e-35 121.9 0.6 3e-20 72.5 0.0 3.0 1 1 2 3 3 3 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.7 ETO18871.1 - 4.7e-10 39.4 0.0 2.5e-08 33.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETO18871.1 - 0.046 13.8 0.0 0.066 13.3 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Peptidase_A17 PF05380.8 ETO18871.1 - 3.1 7.6 5.1 3.8 7.3 1.3 2.5 2 1 1 3 3 3 0 Pao retrotransposon peptidase RRM_6 PF14259.1 ETO18872.1 - 3.9e-16 58.7 0.0 5.5e-09 35.8 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO18872.1 - 8.4e-14 51.1 0.0 3.4e-12 46.0 0.0 2.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO18872.1 - 7.1e-13 47.9 0.0 1.2e-07 31.1 0.0 3.0 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) H_PPase PF03030.11 ETO18873.1 - 3.7e-56 190.7 33.1 2.4e-23 82.3 3.4 4.1 3 1 1 4 4 4 4 Inorganic H+ pyrophosphatase DUF2207 PF09972.4 ETO18873.1 - 3.2 6.2 15.5 2.6 6.5 5.7 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Vfa1 PF08432.5 ETO18874.1 - 0.0073 16.3 1.9 0.01 15.8 1.3 1.1 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Kei1 PF08552.6 ETO18874.1 - 0.048 13.3 0.1 0.067 12.8 0.1 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 dDENN PF03455.14 ETO18875.1 - 2.4e-10 40.3 1.9 8.6e-10 38.5 0.2 2.4 1 1 1 2 2 2 1 dDENN domain PPR_2 PF13041.1 ETO18876.1 - 0.00059 19.7 0.0 0.00097 19.0 0.0 1.3 1 0 0 1 1 1 1 PPR repeat family Med1 PF10744.4 ETO18878.1 - 0.0033 16.2 0.5 0.0033 16.2 0.3 1.0 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 FHIPEP PF00771.15 ETO18878.1 - 0.01 14.2 0.0 0.012 13.9 0.0 1.1 1 0 0 1 1 1 0 FHIPEP family YajC PF02699.10 ETO18878.1 - 0.042 13.5 2.3 0.042 13.5 1.6 2.1 2 0 0 2 2 2 0 Preprotein translocase subunit EphA2_TM PF14575.1 ETO18878.1 - 0.082 13.3 0.3 0.21 12.0 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Conotoxin PF02950.12 ETO18878.1 - 0.12 13.1 2.0 1.1 10.1 0.1 2.4 2 0 0 2 2 2 0 Conotoxin K_trans PF02705.11 ETO18878.1 - 0.14 10.4 0.2 0.14 10.5 0.1 1.2 1 0 0 1 1 1 0 K+ potassium transporter Chordopox_G3 PF06129.7 ETO18878.1 - 0.23 11.6 6.5 0.43 10.7 4.5 1.4 1 0 0 1 1 1 0 Chordopoxvirus G3 protein OATP PF03137.15 ETO18878.1 - 0.27 9.2 3.3 0.39 8.6 2.3 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Ctr PF04145.10 ETO18878.1 - 2 8.4 6.8 6.5 6.7 4.7 1.9 1 1 0 1 1 1 0 Ctr copper transporter family RIC3 PF15361.1 ETO18878.1 - 4.4 7.5 8.0 0.19 11.9 1.7 1.6 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Synaphin PF05835.7 ETO18879.1 - 0.0018 18.4 1.6 0.0026 17.9 1.1 1.4 1 0 0 1 1 1 1 Synaphin protein EpsG PF14897.1 ETO18880.1 - 0.013 14.4 1.2 0.024 13.5 0.9 1.4 1 0 0 1 1 1 0 EpsG family Pacs-1 PF10254.4 ETO18880.1 - 0.019 13.6 0.0 0.033 12.8 0.0 1.4 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein PI3K_1B_p101 PF10486.4 ETO18880.1 - 0.033 11.7 1.1 0.21 9.1 0.2 2.3 2 1 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Apis_Csd PF11671.3 ETO18880.1 - 0.73 9.6 8.1 0.14 11.9 3.1 1.6 2 0 0 2 2 2 0 Complementary sex determiner protein Solute_trans_a PF03619.11 ETO18881.1 - 3e-23 82.5 6.9 4.3e-23 82.0 4.8 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Cullin PF00888.17 ETO18883.1 - 2.2e-13 49.6 6.4 2.6e-13 49.4 4.4 1.0 1 0 0 1 1 1 1 Cullin family DUF21 PF01595.15 ETO18887.1 - 4.8e-26 91.1 2.5 3.7e-20 71.9 3.1 2.3 2 0 0 2 2 2 2 Domain of unknown function DUF21 CBS PF00571.23 ETO18887.1 - 2e-06 27.4 0.2 0.0017 18.1 0.0 3.7 3 1 0 3 3 3 2 CBS domain DUF939 PF06081.6 ETO18887.1 - 0.0051 16.6 0.5 0.014 15.2 0.3 1.7 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF939) DUF21 PF01595.15 ETO18888.1 - 1.9e-12 46.8 4.2 3e-10 39.6 2.9 2.9 1 1 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 ETO18888.1 - 1.2e-08 34.5 0.6 0.00027 20.6 0.0 3.4 3 1 0 3 3 3 2 CBS domain ENTH PF01417.15 ETO18889.1 - 1.9e-17 63.2 0.0 4e-11 42.8 0.0 2.3 2 0 0 2 2 2 2 ENTH domain ANTH PF07651.11 ETO18889.1 - 0.00034 19.3 0.0 0.75 8.4 0.0 2.4 2 0 0 2 2 2 2 ANTH domain Gly-zipper_Omp PF13488.1 ETO18891.1 - 1.5e-08 34.1 99.4 0.074 12.6 11.7 6.6 1 1 3 4 4 4 1 Glycine zipper Rick_17kDa_Anti PF05433.10 ETO18891.1 - 4.1e-06 26.3 103.3 0.0046 16.5 17.6 6.9 2 1 3 5 5 5 3 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.1 ETO18891.1 - 6e-06 25.6 81.3 0.047 13.2 6.8 5.7 1 1 3 4 4 4 2 YMGG-like Gly-zipper TraT PF05818.7 ETO18891.1 - 0.00076 18.9 39.9 0.0069 15.8 1.8 4.0 1 1 3 4 4 4 3 Enterobacterial TraT complement resistance protein Transgly_assoc PF04226.8 ETO18891.1 - 0.37 10.9 115.3 3.9 7.6 15.4 8.1 2 1 4 6 6 6 0 Transglycosylase associated protein DUF2798 PF11391.3 ETO18891.1 - 1.3 8.8 5.9 5.8 6.7 2.7 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2798) Bacteriocin_IIc PF10439.4 ETO18891.1 - 2.4 8.3 93.5 1.5e+04 -63.0 64.8 6.5 1 1 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF3439 PF11921.3 ETO18893.1 - 5.4e-05 22.9 1.9 0.00013 21.6 1.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) DUF2683 PF10884.3 ETO18894.1 - 0.058 13.3 3.1 0.1 12.5 0.0 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF2683) WD40 PF00400.27 ETO18895.1 - 5.4e-16 57.7 6.0 9.7e-09 34.7 0.8 2.7 3 0 0 3 3 3 2 WD domain, G-beta repeat zf-TRAF PF02176.13 ETO18895.1 - 2.7e-05 24.4 2.7 2.7e-05 24.4 1.9 3.4 3 1 1 5 5 5 1 TRAF-type zinc finger Nup160 PF11715.3 ETO18895.1 - 0.00075 17.7 1.8 0.0031 15.7 1.2 1.8 1 1 0 1 1 1 1 Nucleoporin Nup120/160 DUF4592 PF15262.1 ETO18895.1 - 0.034 14.6 2.1 0.066 13.7 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4592) Kelch_6 PF13964.1 ETO18895.1 - 0.12 12.5 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 Kelch motif CENP-B_dimeris PF09026.5 ETO18896.1 - 0.1 12.8 10.3 1.9 8.7 4.6 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF966 PF06136.8 ETO18896.1 - 8.4 5.7 22.1 11 5.3 15.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF966) HrcA PF01628.16 ETO18897.1 - 0.17 11.4 1.8 0.22 11.0 1.3 1.1 1 0 0 1 1 1 0 HrcA protein C terminal domain SelB-wing_3 PF09107.6 ETO18897.1 - 0.19 11.1 3.4 0.54 9.6 0.4 2.3 2 0 0 2 2 2 0 Elongation factor SelB, winged helix RelA_SpoT PF04607.12 ETO18897.1 - 0.23 11.4 5.2 0.053 13.5 1.3 1.7 2 0 0 2 2 2 0 Region found in RelA / SpoT proteins FtsL PF04999.8 ETO18897.1 - 0.41 10.4 2.1 0.73 9.5 1.5 1.5 1 0 0 1 1 1 0 Cell division protein FtsL Secretin_N_2 PF07655.8 ETO18897.1 - 1.1 9.6 11.4 4 7.8 7.9 1.9 1 0 0 1 1 1 0 Secretin N-terminal domain Rab5-bind PF09311.6 ETO18897.1 - 8 6.3 17.0 97 2.7 11.8 2.2 1 1 0 1 1 1 0 Rabaptin-like protein zf-C2H2 PF00096.21 ETO18899.1 - 0.00067 19.8 4.8 0.00067 19.8 3.3 2.8 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-Di19 PF05605.7 ETO18899.1 - 0.002 18.1 5.3 0.0046 17.0 3.6 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 ETO18899.1 - 0.034 14.4 4.3 0.034 14.4 2.9 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_7 PF15269.1 ETO18899.1 - 0.068 13.0 1.2 0.14 12.0 0.9 1.5 1 0 0 1 1 1 0 Zinc-finger zf-C2H2_2 PF12756.2 ETO18899.1 - 0.27 11.3 9.6 0.085 12.9 3.7 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 ETO18899.1 - 3.7 8.0 8.7 17 5.9 2.3 2.6 2 0 0 2 2 2 0 Zinc-finger double domain Peptidase_S9_N PF02897.10 ETO18900.1 - 4.9e-38 130.7 0.0 5.8e-38 130.5 0.0 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain SET PF00856.23 ETO18901.1 - 3.5e-16 59.9 0.0 2.1e-15 57.4 0.0 2.0 1 1 0 1 1 1 1 SET domain SET PF00856.23 ETO18902.1 - 0.00056 20.2 0.3 0.0021 18.3 0.0 1.9 2 1 0 2 2 2 1 SET domain zf-C2H2_4 PF13894.1 ETO18903.1 - 0.072 13.4 13.2 1.2 9.6 2.4 3.4 2 0 0 2 2 2 0 C2H2-type zinc finger RRM_6 PF14259.1 ETO18904.1 - 0.008 16.1 0.0 0.023 14.6 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO18904.1 - 0.012 15.2 0.0 0.035 13.7 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 ETO18905.1 - 7.7e-113 364.8 40.4 3.9e-13 48.7 0.1 12.6 12 0 0 12 12 12 12 WD domain, G-beta repeat PD40 PF07676.7 ETO18905.1 - 3.8e-09 36.0 6.9 4.8 6.9 0.0 9.1 9 0 0 9 9 9 1 WD40-like Beta Propeller Repeat NACHT PF05729.7 ETO18905.1 - 3.5e-08 33.2 0.0 7.4e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PQQ_2 PF13360.1 ETO18905.1 - 1.2e-07 31.4 1.3 0.003 17.0 0.9 4.0 2 1 1 3 3 3 2 PQQ-like domain AAA_18 PF13238.1 ETO18905.1 - 2e-06 28.1 0.2 2e-06 28.1 0.1 5.4 5 1 1 6 6 6 1 AAA domain Gmad1 PF10647.4 ETO18905.1 - 8.2e-05 22.1 0.0 0.6 9.4 0.0 4.3 2 1 2 4 4 4 1 Lipoprotein LpqB beta-propeller domain AAA_22 PF13401.1 ETO18905.1 - 0.00099 19.2 0.0 0.0031 17.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO18905.1 - 0.0043 17.8 0.0 0.0043 17.8 0.0 4.0 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.1 ETO18905.1 - 0.13 12.2 0.0 0.37 10.7 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Resistin PF06954.6 ETO18905.1 - 2 8.7 4.9 71 3.7 0.0 4.3 5 0 0 5 5 4 0 Resistin Proteasome_A_N PF10584.4 ETO18905.1 - 3.2 7.1 12.8 58 3.1 0.1 6.6 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature DUF4339 PF14237.1 ETO18908.1 - 7.8e-05 22.1 0.1 0.37 10.4 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4339) TATR PF03430.8 ETO18908.1 - 0.073 11.7 4.3 0.12 11.0 3.0 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Peroxin-3 PF04882.7 ETO18908.1 - 9.5 4.8 11.0 14 4.2 7.6 1.5 1 1 0 1 1 1 0 Peroxin-3 RGS PF00615.14 ETO18909.1 - 0.015 15.3 0.1 0.015 15.3 0.1 2.1 3 0 0 3 3 3 0 Regulator of G protein signaling domain PAT1 PF09770.4 ETO18909.1 - 0.37 8.9 28.8 0.49 8.5 20.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Muted PF14942.1 ETO18909.1 - 4.2 7.2 12.4 2.2 8.1 0.6 2.4 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein CodY PF06018.9 ETO18910.1 - 0.0011 18.3 1.1 0.0019 17.5 0.8 1.4 1 0 0 1 1 1 1 CodY GAF-like domain DDRGK PF09756.4 ETO18910.1 - 0.0041 16.5 7.3 0.006 16.0 5.0 1.2 1 0 0 1 1 1 1 DDRGK domain Gti1_Pac2 PF09729.4 ETO18910.1 - 0.0052 16.6 1.5 0.0079 16.0 1.0 1.3 1 0 0 1 1 1 1 Gti1/Pac2 family GEMIN8 PF15348.1 ETO18910.1 - 0.0099 15.9 10.1 0.016 15.2 7.0 1.2 1 0 0 1 1 1 1 Gemini of Cajal bodies-associated protein 8 p450 PF00067.17 ETO18910.1 - 0.019 13.4 1.0 0.024 13.1 0.7 1.1 1 0 0 1 1 1 0 Cytochrome P450 Daxx PF03344.10 ETO18910.1 - 0.044 12.2 8.6 0.054 11.9 6.0 1.1 1 0 0 1 1 1 0 Daxx Family Polyoma_coat2 PF00761.15 ETO18910.1 - 0.049 13.1 3.3 0.067 12.6 2.3 1.1 1 0 0 1 1 1 0 Polyomavirus coat protein Myc_N PF01056.13 ETO18910.1 - 0.096 11.8 3.9 0.13 11.4 2.7 1.1 1 0 0 1 1 1 0 Myc amino-terminal region NPR3 PF03666.8 ETO18910.1 - 0.13 10.7 4.7 0.17 10.4 3.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Spore_coat_CotO PF14153.1 ETO18910.1 - 0.14 11.5 9.6 0.23 10.8 6.7 1.3 1 0 0 1 1 1 0 Spore coat protein CotO DUF1168 PF06658.7 ETO18910.1 - 0.23 10.9 14.2 0.4 10.1 9.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Prothymosin PF03247.9 ETO18910.1 - 0.36 10.9 25.2 0.6 10.2 17.5 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family PBP1_TM PF14812.1 ETO18910.1 - 0.62 10.3 11.5 1.4 9.2 8.0 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Methyltransf_12 PF08242.7 ETO18910.1 - 0.8 10.2 4.1 1.9 9.0 2.9 1.7 1 0 0 1 1 1 0 Methyltransferase domain Eapp_C PF10238.4 ETO18910.1 - 1.7 8.5 12.7 3.3 7.5 8.8 1.5 1 0 0 1 1 1 0 E2F-associated phosphoprotein Potyvirid-P3 PF13608.1 ETO18910.1 - 2.7 6.9 8.9 5.3 6.0 5.6 1.6 1 1 1 2 2 2 0 Protein P3 of Potyviral polyprotein Pox_Ag35 PF03286.9 ETO18910.1 - 2.8 7.4 11.1 4.1 6.8 7.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Mem_trans PF03547.13 ETO18910.1 - 3.1 5.9 4.4 4.1 5.6 3.0 1.1 1 0 0 1 1 1 0 Membrane transport protein zf-C2H2 PF00096.21 ETO18911.1 - 0.00017 21.7 6.8 0.19 12.1 0.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETO18911.1 - 0.0012 19.0 9.9 0.029 14.6 0.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger PyrI_C PF02748.10 ETO18911.1 - 0.0049 16.2 2.4 0.011 15.1 1.6 1.6 1 0 0 1 1 1 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF4592 PF15262.1 ETO18911.1 - 0.013 16.0 2.0 0.099 13.1 1.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4592) zf-Di19 PF05605.7 ETO18911.1 - 0.041 14.0 11.3 0.26 11.4 2.5 2.6 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 ETO18911.1 - 0.4 10.3 4.1 2.2 8.0 0.0 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.1 ETO18911.1 - 3 8.2 11.8 0.88 9.9 3.5 2.9 3 0 0 3 3 3 0 Zinc-finger double domain TFIIA PF03153.8 ETO18913.1 - 0.23 11.3 2.3 0.28 11.0 1.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.4 ETO18913.1 - 0.54 9.6 15.1 0.76 9.2 10.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF966 PF06136.8 ETO18913.1 - 0.69 9.2 8.6 0.89 8.9 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Macoilin PF09726.4 ETO18913.1 - 0.93 7.6 9.5 1.2 7.3 6.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Dicty_REP PF05086.7 ETO18913.1 - 1.3 6.6 14.8 1.9 6.1 10.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MSP1_C PF07462.6 ETO18913.1 - 1.5 7.1 11.0 2 6.7 7.6 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus PAP1 PF08601.5 ETO18913.1 - 2.2 7.8 12.8 2.8 7.5 8.9 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 RAP1 PF07218.6 ETO18913.1 - 7 4.6 11.2 9.3 4.1 7.8 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Sec63 PF02889.11 ETO18916.1 - 1.7e-17 63.6 0.0 2.1e-17 63.3 0.0 1.0 1 0 0 1 1 1 1 Sec63 Brl domain VHS PF00790.14 ETO18918.1 - 3.2e-12 46.2 0.1 1.7e-11 43.9 0.0 2.3 1 0 0 1 1 1 1 VHS domain DUF2457 PF10446.4 ETO18918.1 - 0.65 8.6 19.2 1.3 7.6 13.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Zip PF02535.17 ETO18918.1 - 5 6.0 4.3 11 4.8 2.9 1.7 1 1 0 1 1 1 0 ZIP Zinc transporter DUF1317 PF07026.6 ETO18919.1 - 0.077 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1317) SIN1 PF05422.7 ETO18920.1 - 0.0001 21.0 0.1 0.00011 20.9 0.0 1.2 1 0 0 1 1 1 1 Stress-activated map kinase interacting protein 1 (SIN1) DDRGK PF09756.4 ETO18920.1 - 0.1 11.9 1.8 0.53 9.6 0.1 2.0 2 0 0 2 2 2 0 DDRGK domain Type_III_YscX PF09474.5 ETO18921.1 - 0.0052 16.7 1.0 0.0099 15.8 0.7 1.5 1 0 0 1 1 1 1 Type III secretion system YscX (type_III_YscX) ALS2CR8 PF15299.1 ETO18921.1 - 0.079 12.5 1.4 0.13 11.8 1.0 1.3 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Spectrin PF00435.16 ETO18921.1 - 0.082 13.1 10.5 0.82 9.9 1.0 2.5 2 1 1 3 3 3 0 Spectrin repeat Phage_GP20 PF06810.6 ETO18921.1 - 0.32 10.4 8.6 0.52 9.7 5.9 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 Ax_dynein_light PF10211.4 ETO18921.1 - 1.2 8.9 11.9 1.8 8.3 8.2 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain MerR-DNA-bind PF09278.6 ETO18921.1 - 2 8.8 8.6 12 6.3 1.7 2.4 2 0 0 2 2 2 0 MerR, DNA binding RhoGAP PF00620.22 ETO18922.1 - 2.3e-10 40.2 0.5 1.2e-09 37.9 0.4 2.2 1 1 0 1 1 1 1 RhoGAP domain CAML PF14963.1 ETO18924.1 - 0.016 14.6 0.2 0.016 14.6 0.2 2.0 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand Hum_adeno_E3A PF05393.6 ETO18924.1 - 0.071 12.7 0.0 0.31 10.7 0.0 2.1 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein zf-4CXXC_R1 PF10497.4 ETO18925.1 - 1.2e-06 28.5 19.1 1.3e-06 28.4 12.2 1.8 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Abhydrolase_1 PF00561.15 ETO18926.1 - 7.4e-08 32.2 0.0 5.1e-07 29.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETO18926.1 - 5.3e-07 29.7 0.0 3e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETO18926.1 - 0.04 13.6 0.0 0.81 9.4 0.0 2.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family VirJ PF06057.6 ETO18926.1 - 0.12 12.1 0.1 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) YqcI_YcgG PF08892.6 ETO18927.1 - 0.043 13.3 1.1 0.071 12.6 0.8 1.2 1 0 0 1 1 1 0 YqcI/YcgG family RVT_1 PF00078.22 ETO18928.1 - 2.5e-09 36.8 0.9 2.2e-08 33.7 0.2 2.8 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4010 PF13194.1 ETO18929.1 - 0.25 10.6 0.0 0.44 9.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) Erf4 PF10256.4 ETO18930.1 - 0.093 12.5 0.2 0.26 11.1 0.1 1.8 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family PX PF00787.19 ETO18934.1 - 5.1e-20 71.3 0.7 1.4e-19 69.9 0.0 2.1 3 0 0 3 3 3 1 PX domain Vps5 PF09325.5 ETO18934.1 - 0.006 15.8 9.2 0.049 12.8 2.3 2.5 1 1 1 2 2 2 2 Vps5 C terminal like DegS PF05384.6 ETO18934.1 - 0.018 14.2 3.7 3.9 6.6 0.0 3.2 3 0 0 3 3 3 0 Sensor protein DegS Occludin_ELL PF07303.8 ETO18935.1 - 0.0053 17.4 3.4 0.0053 17.4 2.3 3.0 1 1 1 2 2 2 1 Occludin homology domain ATG16 PF08614.6 ETO18935.1 - 0.021 14.6 28.3 0.29 10.9 6.9 3.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.5 ETO18935.1 - 0.15 12.2 19.5 4.3 7.4 3.2 3.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family NpwBP PF12622.2 ETO18935.1 - 0.15 12.5 3.0 0.36 11.3 0.8 2.7 2 0 0 2 2 2 0 mRNA biogenesis factor DUF4140 PF13600.1 ETO18935.1 - 0.19 12.1 8.6 5.2 7.5 1.4 2.8 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) CCDC-167 PF15188.1 ETO18935.1 - 0.75 9.7 13.9 0.54 10.2 1.5 3.4 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 SlyX PF04102.7 ETO18935.1 - 0.89 9.9 11.9 3.7 7.9 0.6 3.6 3 0 0 3 3 3 0 SlyX IncA PF04156.9 ETO18935.1 - 2.3 7.7 29.3 0.29 10.6 7.9 2.5 2 1 1 3 3 3 0 IncA protein Cep57_CLD_2 PF14197.1 ETO18935.1 - 2.5 8.0 12.2 0.9 9.5 0.6 3.1 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Spc7 PF08317.6 ETO18935.1 - 2.9 6.4 26.7 4.1 5.9 5.2 3.5 2 1 0 3 3 3 0 Spc7 kinetochore protein HALZ PF02183.13 ETO18935.1 - 3.2 7.5 10.3 5.1 6.9 0.3 3.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper ADIP PF11559.3 ETO18935.1 - 5 7.0 23.3 4.5 7.1 6.0 2.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding COG2 PF06148.6 ETO18935.1 - 7.5 6.4 11.2 0.99 9.2 0.9 3.3 2 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 TLD PF07534.11 ETO18936.1 - 1.7e-14 54.0 0.4 3.1e-14 53.1 0.3 1.4 1 0 0 1 1 1 1 TLD fn3 PF00041.16 ETO18936.1 - 0.02 15.0 0.1 0.044 13.9 0.0 1.6 2 0 0 2 2 2 0 Fibronectin type III domain Condensin2nSMC PF12422.3 ETO18936.1 - 0.076 12.7 0.1 0.25 11.0 0.0 1.7 2 0 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit Ribosomal_L22e PF01776.12 ETO18936.1 - 1.2 9.1 5.2 0.63 10.0 0.7 2.1 1 1 1 2 2 2 0 Ribosomal L22e protein family zf-CCHC_2 PF13696.1 ETO18937.1 - 7.7e-15 54.0 29.8 2e-05 23.9 2.3 3.4 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC PF00098.18 ETO18937.1 - 3.5e-08 33.0 28.3 0.0035 17.1 2.7 3.5 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.1 ETO18937.1 - 9.9e-06 25.2 22.7 0.014 15.1 1.0 3.6 1 1 2 3 3 3 3 Zinc knuckle zf-CCHC_4 PF14392.1 ETO18937.1 - 0.0019 17.8 20.5 0.33 10.6 0.1 3.5 3 0 0 3 3 3 3 Zinc knuckle RhoGEF PF00621.15 ETO18938.1 - 1.6e-17 63.9 1.8 2.6e-17 63.2 1.3 1.3 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.16 ETO18938.1 - 6e-07 29.2 0.8 1.3e-06 28.1 0.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 ETO18938.1 - 0.078 13.1 0.1 0.39 10.9 0.0 2.0 2 0 0 2 2 2 0 PH domain La PF05383.12 ETO18939.1 - 5.3e-08 32.5 0.0 1.2e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 ETO18939.1 - 0.00029 20.7 0.0 0.025 14.5 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO18939.1 - 0.00029 20.4 0.0 1.1 8.9 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Secretin_N_2 PF07655.8 ETO18939.1 - 4.7 7.6 51.8 1.1 9.7 1.1 3.4 3 0 0 3 3 3 0 Secretin N-terminal domain STAS PF01740.16 ETO18940.1 - 1.2e-19 69.8 0.1 2.1e-19 69.0 0.1 1.4 1 0 0 1 1 1 1 STAS domain Sulfate_transp PF00916.15 ETO18940.1 - 2.8e-18 65.9 0.1 5.1e-18 65.0 0.1 1.4 1 0 0 1 1 1 1 Sulfate transporter family Atrophin-1 PF03154.10 ETO18941.1 - 0.0021 16.3 0.9 0.0021 16.3 0.7 2.3 1 1 1 2 2 2 1 Atrophin-1 family MIP-T3 PF10243.4 ETO18941.1 - 0.011 14.2 21.6 0.013 14.0 15.0 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1777 PF08648.7 ETO18941.1 - 0.021 14.5 55.2 0.17 11.5 22.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1777) DUF3827 PF12877.2 ETO18941.1 - 4.7 5.1 8.1 5.5 4.9 5.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF4120 PF13496.1 ETO18942.1 - 0.085 12.8 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4120) Peptidase_C14 PF00656.17 ETO18943.1 - 8.7e-05 22.3 0.4 0.00031 20.5 0.3 1.9 1 1 0 1 1 1 1 Caspase domain TPR_12 PF13424.1 ETO18944.1 - 2.2e-55 184.5 12.4 8.6e-18 64.0 1.3 3.1 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO18944.1 - 1.2e-20 72.9 10.5 5e-11 42.0 0.2 2.9 1 1 2 3 3 3 3 TPR repeat TPR_7 PF13176.1 ETO18944.1 - 1.3e-20 71.5 0.4 6.9e-07 28.6 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO18944.1 - 2.3e-17 61.4 15.8 7.6e-05 22.2 0.1 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO18944.1 - 1.6e-16 59.5 0.0 0.0014 18.5 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO18944.1 - 1.8e-16 58.6 9.4 0.00016 21.3 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO18944.1 - 6e-16 57.3 15.0 3.3e-06 26.4 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO18944.1 - 3e-09 36.3 5.2 0.01 15.9 0.1 3.9 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO18944.1 - 7.6e-06 26.4 0.0 0.0065 17.1 0.0 2.5 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO18944.1 - 7.3e-05 22.9 0.6 11 6.7 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO18944.1 - 0.00071 19.9 0.0 7.6 7.4 0.0 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat DUF2225 PF09986.4 ETO18944.1 - 0.006 16.0 2.6 0.1 12.0 0.3 2.3 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) Lyase_1 PF00206.15 ETO18945.1 - 2.3e-07 30.2 0.0 2.9e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Lyase DUF1072 PF06380.6 ETO18946.1 - 0.05 13.2 0.1 0.05 13.2 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1072) PHO4 PF01384.15 ETO18946.1 - 0.51 8.9 4.9 0.77 8.3 3.4 1.3 1 0 0 1 1 1 0 Phosphate transporter family Herpes_LMP1 PF05297.6 ETO18946.1 - 4.5 6.0 14.2 6 5.6 9.8 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Trypan_PARP PF05887.6 ETO18947.1 - 0.0017 18.1 2.6 0.0028 17.4 1.8 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DUF2634 PF10934.3 ETO18947.1 - 0.0068 16.1 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2634) Prd1-P2 PF09214.6 ETO18947.1 - 0.0082 14.7 0.9 0.0082 14.7 0.6 1.5 2 0 0 2 2 2 1 Bacteriophage Prd1, adsorption protein P2 MIP-T3 PF10243.4 ETO18948.1 - 0.0035 15.9 31.7 0.0039 15.7 22.0 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Drf_GBD PF06371.8 ETO18948.1 - 0.022 14.0 0.4 0.022 14.0 0.3 2.1 1 1 1 2 2 2 0 Diaphanous GTPase-binding Domain SRPRB PF09439.5 ETO18950.1 - 1.9e-15 56.5 0.2 4.6e-13 48.7 0.0 2.4 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 ETO18950.1 - 0.00012 21.9 0.0 0.00022 21.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 ETO18950.1 - 0.0076 15.5 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 ETO18950.1 - 0.016 15.6 0.0 0.035 14.6 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein Septin PF00735.13 ETO18950.1 - 0.032 13.2 0.0 0.049 12.6 0.0 1.3 1 0 0 1 1 1 0 Septin Dynamin_N PF00350.18 ETO18950.1 - 0.033 14.0 0.0 0.072 12.9 0.0 1.6 1 0 0 1 1 1 0 Dynamin family GTP_EFTU PF00009.22 ETO18950.1 - 0.041 13.3 0.4 0.16 11.3 0.0 2.1 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF939 PF06081.6 ETO18950.1 - 6.1 6.7 12.4 0.085 12.7 1.7 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF939) DUF829 PF05705.9 ETO18951.1 - 2.2e-32 112.7 0.2 3.3e-32 112.0 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 ETO18951.1 - 0.00018 21.4 0.0 0.00026 20.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETO18951.1 - 0.097 12.4 0.0 0.18 11.5 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family F-box-like PF12937.2 ETO18952.1 - 0.0022 17.6 0.5 0.0033 17.1 0.3 1.2 1 0 0 1 1 1 1 F-box-like zf-C2H2 PF00096.21 ETO18953.1 - 9.1e-07 28.8 10.7 0.0093 16.2 0.3 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETO18953.1 - 3.1e-05 24.0 2.8 3.1e-05 24.0 1.9 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 ETO18953.1 - 0.00048 20.2 12.0 0.012 15.8 0.2 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger Spore_YhcN_YlaJ PF09580.5 ETO18953.1 - 2.1 8.4 29.8 3.9 7.5 12.8 2.6 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) zf-C2H2_jaz PF12171.3 ETO18953.1 - 4.1 7.6 13.3 1.4 9.1 0.4 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding HrcA PF01628.16 ETO18954.1 - 0.017 14.7 0.2 0.026 14.0 0.1 1.2 1 0 0 1 1 1 0 HrcA protein C terminal domain RPEL PF02755.10 ETO18954.1 - 0.029 13.6 0.4 0.079 12.3 0.3 1.7 1 0 0 1 1 1 0 RPEL repeat NUDIX_4 PF14815.1 ETO18954.1 - 0.085 12.2 0.2 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 NUDIX domain Lipase_bact_N PF12262.3 ETO18956.1 - 0.014 14.6 0.2 0.023 13.8 0.1 1.3 1 0 0 1 1 1 0 Bacterial virulence factor lipase N-terminal CBM27 PF09212.5 ETO18956.1 - 0.052 13.5 0.1 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding module 27 Tom37_C PF11801.3 ETO18956.1 - 0.06 13.2 3.7 0.066 13.0 2.0 1.4 1 1 0 1 1 1 0 Tom37 C-terminal domain DUF2956 PF11169.3 ETO18956.1 - 3.2 7.7 9.9 0.6 10.0 2.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) TIP_N PF12457.3 ETO18957.1 - 0.0071 16.4 3.2 0.43 10.6 0.1 2.6 2 0 0 2 2 2 2 Tuftelin interacting protein N terminal WD40 PF00400.27 ETO18958.1 - 1.1e-49 164.5 18.8 8.8e-12 44.4 0.4 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO18958.1 - 3.9e-09 35.1 3.1 0.034 12.2 0.0 5.2 1 1 4 6 6 6 5 Nucleoporin Nup120/160 DUF832 PF05734.6 ETO18959.1 - 0.0066 15.6 0.7 0.024 13.8 0.5 1.8 1 1 0 1 1 1 1 Herpesvirus protein of unknown function (DUF832) Chordopox_A33R PF05966.7 ETO18959.1 - 0.059 12.1 1.2 0.091 11.5 0.9 1.3 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Acetyltransf_7 PF13508.1 ETO18959.1 - 0.12 12.5 0.2 1.6 8.9 0.0 2.1 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Arm PF00514.18 ETO18960.1 - 2.2e-15 55.8 1.8 0.0011 18.7 0.0 8.1 10 1 0 10 10 10 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 ETO18960.1 - 5.6e-06 26.5 0.0 0.018 15.2 0.0 4.2 3 2 1 4 4 4 1 HEAT repeats HEAT_EZ PF13513.1 ETO18960.1 - 5.8e-06 26.6 0.0 0.002 18.5 0.0 4.3 4 0 0 4 4 4 1 HEAT-like repeat Arm_2 PF04826.8 ETO18960.1 - 0.00021 20.5 1.7 0.14 11.2 0.0 3.7 2 2 2 4 4 4 2 Armadillo-like HEAT PF02985.17 ETO18960.1 - 0.009 16.0 0.2 0.97 9.6 0.0 4.1 5 0 0 5 5 5 1 HEAT repeat Atx10homo_assoc PF09759.4 ETO18960.1 - 0.015 15.0 0.1 0.59 9.8 0.0 2.6 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain DUF1537 PF07005.6 ETO18960.1 - 0.17 11.5 0.0 0.75 9.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF1537 WD40 PF00400.27 ETO18961.1 - 1.1e-48 161.4 27.7 2.9e-12 45.9 0.0 6.2 5 1 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO18961.1 - 4.4e-09 35.0 2.3 0.039 12.1 0.0 4.6 1 1 2 3 3 3 3 Nucleoporin Nup120/160 DUF851 PF05867.6 ETO18961.1 - 0.032 13.4 0.1 1.2 8.3 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF851) Baculo_VP39 PF04501.7 ETO18961.1 - 0.13 11.2 1.8 2.6 6.9 0.0 3.1 2 1 2 5 5 5 0 Baculovirus major capsid protein VP39 AAA PF00004.24 ETO18962.1 - 9e-41 139.1 0.0 1.5e-40 138.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 ETO18962.1 - 3.7e-06 26.1 0.1 4.3e-05 22.6 0.0 2.0 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 ETO18962.1 - 3.9e-06 26.9 0.1 0.0002 21.4 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 ETO18962.1 - 1.5e-05 25.1 0.4 0.0015 18.6 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 ETO18962.1 - 3.2e-05 23.9 0.0 7.6e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 ETO18962.1 - 7.3e-05 22.5 0.1 0.00036 20.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 ETO18962.1 - 0.00069 18.6 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 ETO18962.1 - 0.0027 17.4 0.1 0.0069 16.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 ETO18962.1 - 0.0031 16.9 0.0 0.0058 16.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 ETO18962.1 - 0.0054 16.6 0.1 0.015 15.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 ETO18962.1 - 0.0062 15.7 0.0 0.016 14.3 0.0 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 ETO18962.1 - 0.0076 15.7 0.0 0.06 12.8 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 ETO18962.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 ETO18962.1 - 0.011 15.1 1.0 0.31 10.4 0.1 2.3 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.7 ETO18962.1 - 0.014 14.5 0.0 0.073 12.1 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin PhoH PF02562.11 ETO18962.1 - 0.015 14.5 0.0 0.065 12.4 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_17 PF13207.1 ETO18962.1 - 0.016 15.9 0.1 0.046 14.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 ETO18962.1 - 0.017 15.3 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 ETO18962.1 - 0.02 14.4 0.1 0.036 13.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 ETO18962.1 - 0.024 14.2 0.1 0.95 9.0 0.0 2.5 1 1 1 2 2 2 0 NACHT domain KaiC PF06745.8 ETO18962.1 - 0.048 12.7 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.1 ETO18962.1 - 0.059 13.6 0.0 0.19 12.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.8 ETO18962.1 - 0.059 12.0 0.0 0.088 11.5 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Arch_ATPase PF01637.13 ETO18962.1 - 0.062 12.9 0.1 0.69 9.5 0.1 2.2 1 1 0 1 1 1 0 Archaeal ATPase Sigma54_activ_2 PF14532.1 ETO18962.1 - 0.081 12.9 0.0 0.19 11.8 0.0 1.6 2 0 0 2 2 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 ETO18962.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain CPT PF07931.7 ETO18962.1 - 0.16 11.6 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Spc7 PF08317.6 ETO18963.1 - 0.00015 20.5 1.1 0.0002 20.1 0.8 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein TPD52 PF04201.10 ETO18963.1 - 0.0059 16.3 2.1 0.0089 15.7 1.4 1.2 1 0 0 1 1 1 1 Tumour protein D52 family AbiH PF14253.1 ETO18963.1 - 0.02 14.4 0.4 0.03 13.9 0.3 1.2 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH DUF4446 PF14584.1 ETO18963.1 - 0.026 14.3 2.9 0.044 13.6 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF3512 PF12024.3 ETO18963.1 - 0.057 12.7 0.7 0.082 12.1 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3512) IBN_N PF03810.14 ETO18963.1 - 0.058 13.3 2.9 1.2 9.0 0.0 2.7 3 0 0 3 3 3 0 Importin-beta N-terminal domain BTAD PF03704.12 ETO18963.1 - 0.096 12.9 0.3 0.18 12.1 0.2 1.4 1 0 0 1 1 1 0 Bacterial transcriptional activator domain ABC_tran_2 PF12848.2 ETO18963.1 - 5.7 6.8 11.0 3.7 7.4 5.4 2.3 3 1 0 3 3 3 0 ABC transporter Fib_alpha PF08702.5 ETO18963.1 - 5.9 7.0 8.5 1.2 9.2 2.9 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Ubiq_cyt_C_chap PF03981.7 ETO18964.1 - 6.9e-05 22.7 0.1 0.00011 22.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone ubiquitin PF00240.18 ETO18966.1 - 0.036 13.4 0.4 0.082 12.3 0.3 1.6 1 0 0 1 1 1 0 Ubiquitin family VWD PF00094.20 ETO18967.1 - 7.2e-11 42.5 0.2 2.8e-10 40.6 0.1 2.0 1 1 0 1 1 1 1 von Willebrand factor type D domain AMOP PF03782.12 ETO18967.1 - 1.3e-06 28.4 3.1 2.8e-06 27.4 2.2 1.5 1 0 0 1 1 1 1 AMOP domain Choline_kinase PF01633.15 ETO18968.1 - 1.3e-25 90.2 4.0 1.6e-25 89.9 2.8 1.0 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 ETO18968.1 - 1.6e-09 37.8 0.1 7.9e-07 29.0 0.0 2.0 2 0 0 2 2 2 2 Phosphotransferase enzyme family Sec5 PF15469.1 ETO18968.1 - 0.1 12.3 1.5 0.18 11.5 0.5 1.7 2 0 0 2 2 2 0 Exocyst complex component Sec5 DUF3384 PF11864.3 ETO18969.1 - 0.0051 15.3 0.1 0.0094 14.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) DUF3337 PF11816.3 ETO18970.1 - 0.01 15.2 20.0 0.013 14.9 13.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) Peptidase_S64 PF08192.6 ETO18970.1 - 5.2 5.2 14.9 5.7 5.1 10.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF874 PF05917.6 ETO18971.1 - 0.023 13.5 0.2 0.027 13.3 0.2 1.0 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) Herpes_US9 PF06072.6 ETO18971.1 - 0.08 12.7 1.1 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Adaptin_N PF01602.15 ETO18973.1 - 1.6e-23 82.8 0.0 1.9e-23 82.5 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 ETO18973.1 - 2.1e-07 30.9 0.0 3e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 ETO18973.1 - 5.4e-05 22.9 1.4 0.11 12.6 0.0 3.6 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 ETO18973.1 - 0.00015 21.9 0.0 0.01 16.0 0.0 2.1 1 1 1 2 2 2 2 HEAT repeats Arm PF00514.18 ETO18973.1 - 0.011 15.5 1.2 0.71 9.7 0.0 2.8 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Auxin_canalis PF05703.6 ETO18974.1 - 0.053 13.3 0.8 0.064 13.0 0.5 1.1 1 0 0 1 1 1 0 Auxin canalisation DUF3587 PF12132.3 ETO18974.1 - 0.078 12.2 1.9 0.096 11.9 1.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3587) DUF4631 PF15450.1 ETO18974.1 - 0.13 10.5 4.3 0.15 10.3 3.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4631) EST1_DNA_bind PF10373.4 ETO18974.1 - 0.14 11.3 0.9 0.18 10.9 0.7 1.2 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain SAP PF02037.22 ETO18975.1 - 1.1e-09 37.5 0.8 2.6e-09 36.3 0.6 1.7 1 0 0 1 1 1 1 SAP domain Pex14_N PF04695.8 ETO18975.1 - 0.051 13.6 1.1 0.23 11.5 0.0 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAP_PilO PF06864.7 ETO18975.1 - 0.063 11.6 0.1 0.081 11.2 0.1 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) Phage_30_3 PF08010.6 ETO18975.1 - 0.071 12.5 0.2 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 GidB PF02527.10 ETO18976.1 - 0.13 11.3 3.9 0.23 10.5 2.7 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G PBP1_TM PF14812.1 ETO18976.1 - 6.4 7.1 6.6 1.7 9.0 1.0 2.3 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ly49 PF08391.5 ETO18976.1 - 7.1 6.7 9.2 26 4.9 6.4 2.1 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region CENP-F_leu_zip PF10473.4 ETO18977.1 - 0.00013 21.7 39.1 0.00052 19.8 3.5 3.6 2 1 2 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2353 PF09789.4 ETO18977.1 - 0.0011 18.3 28.9 0.03 13.5 13.1 2.4 2 0 0 2 2 2 2 Uncharacterized coiled-coil protein (DUF2353) ERM PF00769.14 ETO18977.1 - 0.0013 18.3 35.4 0.11 12.0 13.9 2.2 1 1 1 2 2 2 2 Ezrin/radixin/moesin family Filament PF00038.16 ETO18977.1 - 0.0062 16.0 21.3 0.0062 16.0 14.8 2.4 2 1 1 3 3 3 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 ETO18977.1 - 0.01 15.5 21.6 0.01 15.5 15.0 3.6 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.3 ETO18977.1 - 0.013 15.2 33.8 0.65 9.7 14.0 3.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Reo_sigmaC PF04582.7 ETO18977.1 - 0.02 14.0 6.6 0.51 9.4 0.8 2.3 1 1 0 2 2 2 0 Reovirus sigma C capsid protein DUF3584 PF12128.3 ETO18977.1 - 0.023 12.0 29.7 0.03 11.6 20.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Tropomyosin_1 PF12718.2 ETO18977.1 - 0.026 14.3 36.4 0.57 10.0 16.8 2.3 1 1 1 2 2 2 0 Tropomyosin like NPV_P10 PF05531.7 ETO18977.1 - 0.069 13.4 18.0 0.052 13.8 2.7 3.7 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein bZIP_1 PF00170.16 ETO18977.1 - 0.077 12.9 0.1 0.077 12.9 0.1 5.2 1 1 3 5 5 5 0 bZIP transcription factor APG6 PF04111.7 ETO18977.1 - 0.12 11.3 36.8 1 8.3 14.1 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 BicD PF09730.4 ETO18977.1 - 0.97 7.7 34.8 0.066 11.5 20.5 1.5 2 0 0 2 2 2 0 Microtubule-associated protein Bicaudal-D HAUS6_N PF14661.1 ETO18977.1 - 1.5 8.1 26.4 0.52 9.6 4.4 2.6 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus WXG100 PF06013.7 ETO18977.1 - 2.1 8.4 10.7 0.86 9.6 0.2 3.7 2 2 2 4 4 4 0 Proteins of 100 residues with WXG Baculo_PEP_C PF04513.7 ETO18977.1 - 3.9 7.3 14.9 1.4 8.7 3.9 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3450 PF11932.3 ETO18977.1 - 4 6.6 31.5 0.13 11.4 4.6 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Atg14 PF10186.4 ETO18977.1 - 5.5 5.8 36.4 2 7.3 11.2 2.5 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 ETO18977.1 - 5.6 5.5 35.1 7.6 5.0 13.0 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein FlaC_arch PF05377.6 ETO18977.1 - 6.6 6.7 13.1 7.3 6.5 3.5 3.8 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) ADIP PF11559.3 ETO18977.1 - 8.3 6.2 43.3 0.82 9.5 8.0 3.2 2 1 3 5 5 4 0 Afadin- and alpha -actinin-Binding DUF948 PF06103.6 ETO18977.1 - 9.9 6.1 16.2 0.39 10.6 1.2 3.4 2 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Kinesin PF00225.18 ETO18978.1 - 2.1e-22 79.2 1.4 2.9e-22 78.8 1.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Metallophos PF00149.23 ETO18979.1 - 1.8e-25 89.4 0.0 2.2e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 ETO18979.1 - 0.0024 17.7 0.0 0.003 17.4 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PDEase_I PF00233.14 ETO18980.1 - 4.8e-38 131.2 1.3 2.9e-27 95.9 0.0 2.4 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase SCF PF02404.10 ETO18981.1 - 0.076 12.1 0.3 0.28 10.3 0.0 2.0 1 1 0 1 1 1 0 Stem cell factor PhoU_div PF01865.11 ETO18981.1 - 0.22 10.6 3.1 0.13 11.4 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF47 DUF872 PF05915.7 ETO18981.1 - 0.23 11.3 8.2 0.24 11.2 0.2 2.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) TFIIS_M PF07500.9 ETO18981.1 - 0.32 11.0 3.2 5 7.2 0.1 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS), central domain SecA_DEAD PF07517.9 ETO18981.1 - 0.59 9.3 4.2 1.3 8.3 0.1 2.0 2 0 0 2 2 2 0 SecA DEAD-like domain DUF1469 PF07332.6 ETO18981.1 - 0.8 9.4 8.6 0.71 9.6 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF973 PF06157.6 ETO18981.1 - 1.2 7.9 13.7 0.41 9.5 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF973) DUF308 PF03729.8 ETO18981.1 - 2.1 8.4 16.5 0.3 11.1 2.5 2.4 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) Neurensin PF14927.1 ETO18981.1 - 2.1 7.7 9.0 24 4.2 0.0 3.3 3 0 0 3 3 3 0 Neurensin DUF605 PF04652.11 ETO18982.1 - 3e-29 102.6 4.6 3.3e-29 102.4 3.2 1.0 1 0 0 1 1 1 1 Vta1 like USP8_dimer PF08969.6 ETO18982.1 - 0.089 12.7 0.6 0.43 10.5 0.0 2.0 1 1 0 2 2 2 0 USP8 dimerisation domain ResIII PF04851.10 ETO18983.1 - 2.4e-11 43.8 1.5 4e-11 43.0 0.9 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 ETO18983.1 - 7e-09 35.3 1.3 1e-08 34.8 0.1 1.8 2 1 0 2 2 2 1 DEAD/DEAH box helicase Ni_hydr_CYTB PF01292.15 ETO18984.1 - 0.018 14.4 2.1 0.16 11.3 1.5 2.3 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 zf-DHHC PF01529.15 ETO18984.1 - 0.41 10.0 4.3 0.081 12.3 0.2 1.8 2 0 0 2 2 2 0 DHHC palmitoyltransferase Acyl_transf_3 PF01757.17 ETO18984.1 - 0.45 9.3 9.9 2.5 6.8 6.9 1.9 1 1 0 1 1 1 0 Acyltransferase family Oxidored_q3 PF00499.15 ETO18984.1 - 3.3 7.4 12.5 18 5.1 8.4 2.2 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Ank PF00023.25 ETO18985.1 - 3.5e-08 32.8 0.1 0.0023 17.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 ETO18985.1 - 2e-07 31.0 0.4 1.3e-06 28.4 0.1 1.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO18985.1 - 1.2e-06 28.7 0.0 2.4e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO18985.1 - 2.7e-06 27.7 0.2 6.8e-06 26.4 0.2 1.7 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO18985.1 - 7.4e-06 25.7 0.1 0.021 15.0 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat TPR_11 PF13414.1 ETO18986.1 - 1.2e-05 24.8 1.4 1.2e-05 24.8 1.0 2.0 1 1 1 2 2 2 1 TPR repeat TPR_17 PF13431.1 ETO18986.1 - 3e-05 23.8 2.3 0.028 14.6 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO18986.1 - 0.0004 20.7 0.1 0.00098 19.5 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO18986.1 - 0.0019 17.9 2.0 0.0023 17.6 0.2 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO18986.1 - 0.0099 16.1 1.2 0.026 14.8 0.9 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO18986.1 - 0.019 15.5 0.5 0.036 14.7 0.3 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETO18986.1 - 0.028 14.1 0.7 0.14 12.0 0.2 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat AgrB PF04647.10 ETO18986.1 - 0.041 12.9 0.1 0.06 12.3 0.0 1.2 1 0 0 1 1 1 0 Accessory gene regulator B Fis1_TPR_C PF14853.1 ETO18986.1 - 0.043 13.6 0.2 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.1 ETO18986.1 - 0.053 13.4 1.6 0.1 12.5 0.4 1.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETO18986.1 - 0.13 11.8 0.3 0.13 11.8 0.2 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 ETO18986.1 - 0.4 10.8 7.0 0.34 11.0 2.3 2.4 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Glucosamine_iso PF01182.15 ETO18987.1 - 8e-46 156.2 0.0 9.9e-46 155.9 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Pex14_N PF04695.8 ETO18989.1 - 0.0082 16.1 1.2 0.014 15.3 0.8 1.5 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region CobT PF06213.7 ETO18989.1 - 0.097 11.7 3.5 0.16 11.1 2.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2457 PF10446.4 ETO18989.1 - 0.11 11.1 7.4 0.19 10.4 2.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Raftlin PF15250.1 ETO18989.1 - 3 6.2 9.7 3.2 6.1 6.1 1.3 1 1 0 1 1 1 0 Raftlin Tetraspannin PF00335.15 ETO18989.1 - 4.7 6.4 6.1 8.7 5.5 4.2 1.4 1 0 0 1 1 1 0 Tetraspanin family Secretin_N_2 PF07655.8 ETO18989.1 - 6.8 7.1 25.2 27 5.2 17.5 2.0 1 0 0 1 1 1 0 Secretin N-terminal domain DUF695 PF05117.7 ETO18990.1 - 0.074 12.9 0.5 0.45 10.4 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF695) PAZ_siRNAbind PF12212.3 ETO18991.1 - 0.019 14.6 0.9 0.15 11.7 0.6 2.5 1 1 0 1 1 1 0 Piwi/Argonaute/Zwille siRNA-binding domain DUF1310 PF07006.6 ETO18992.1 - 0.086 12.3 0.3 0.1 12.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1310) APG5 PF04106.7 ETO18993.1 - 6.3e-42 143.2 0.4 6.3e-42 143.2 0.3 1.6 2 0 0 2 2 2 1 Autophagy protein Apg5 WBS_methylT PF12589.3 ETO18993.1 - 0.0053 17.2 6.4 0.01 16.3 4.4 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Acyl-CoA_dh_1 PF00441.19 ETO18994.1 - 5.3e-31 107.7 0.2 8.8e-31 107.0 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 ETO18994.1 - 1.4e-12 48.0 0.0 2.2e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 ETO18994.1 - 5e-10 38.7 0.0 1.1e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DUF1973 PF09315.6 ETO18994.1 - 0.11 11.9 0.1 0.25 10.7 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1973) DUF4359 PF14271.1 ETO18995.1 - 0.008 16.5 0.1 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4359) DUF1313 PF07011.6 ETO18997.1 - 0.056 13.1 0.6 0.12 12.0 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1313) DUF2481 PF10654.4 ETO18997.1 - 0.08 12.6 2.0 0.13 11.9 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2481) DUF310 PF03750.8 ETO18997.1 - 0.14 12.3 0.4 0.32 11.2 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF310) FA_hydroxylase PF04116.8 ETO18998.1 - 5.6e-12 46.0 25.9 9.1e-12 45.3 18.0 1.3 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily BLYB PF05289.6 ETO18998.1 - 0.19 11.5 0.8 0.35 10.6 0.1 1.8 1 1 1 2 2 2 0 Borrelia hemolysin accessory protein HAD_2 PF13419.1 ETO18999.1 - 6.7e-09 36.2 0.0 1.3e-06 28.7 0.0 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ETO18999.1 - 9.2e-06 25.2 0.0 1.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.13 ETO18999.1 - 0.027 14.1 0.1 0.077 12.6 0.0 1.7 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase Apis_Csd PF11671.3 ETO19000.1 - 0.35 10.6 7.1 0.34 10.7 0.4 2.4 2 0 0 2 2 2 0 Complementary sex determiner protein DUF1049 PF06305.6 ETO19001.1 - 0.2 11.1 1.7 0.6 9.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) CCDC66 PF15236.1 ETO19001.1 - 0.52 9.9 33.6 2.2 7.8 23.3 2.0 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 66 BCCT PF02028.12 ETO19004.1 - 0.16 10.1 1.5 0.21 9.7 1.1 1.1 1 0 0 1 1 1 0 BCCT family transporter SDA1 PF05285.7 ETO19004.1 - 2 7.6 8.2 2.8 7.1 5.7 1.1 1 0 0 1 1 1 0 SDA1 NESP55 PF06390.7 ETO19004.1 - 6.3 6.0 10.4 3 7.1 5.6 1.5 1 1 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) SHMT PF00464.14 ETO19006.1 - 1.4e-137 458.3 0.1 3.7e-112 374.6 0.0 3.1 1 1 1 3 3 3 3 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 ETO19006.1 - 0.099 11.7 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase tRNA_m1G_MT PF01746.16 ETO19007.1 - 3.7e-13 49.4 0.1 1.1e-12 47.9 0.0 1.8 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Adeno_terminal PF02459.10 ETO19007.1 - 2.8e-05 22.5 3.3 2.8e-05 22.5 2.3 1.6 1 1 1 2 2 2 1 Adenoviral DNA terminal protein DUF1754 PF08555.5 ETO19008.1 - 0.0091 16.5 9.8 0.0091 16.5 6.8 2.5 3 0 0 3 3 3 1 Eukaryotic family of unknown function (DUF1754) Glutaredoxin2_C PF04399.8 ETO19008.1 - 0.043 13.4 1.5 2 7.9 0.5 2.4 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain DUF1043 PF06295.7 ETO19008.1 - 0.87 9.2 8.0 0.13 11.9 0.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) DUF1604 PF07713.8 ETO19009.1 - 3.1e-17 62.1 0.1 3.1e-17 62.1 0.1 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.18 ETO19009.1 - 0.012 15.3 0.5 0.026 14.3 0.4 1.5 1 0 0 1 1 1 0 G-patch domain Myosin_head PF00063.16 ETO19010.1 - 1.6e-45 155.4 0.8 1.9e-45 155.1 0.6 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) RNA_helicase PF00910.17 ETO19010.1 - 0.018 15.2 0.3 0.074 13.2 0.2 1.9 1 1 0 1 1 1 0 RNA helicase DUF1950 PF09187.5 ETO19011.1 - 0.15 12.1 1.0 0.57 10.3 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function(DUF1950) Ras PF00071.17 ETO19012.1 - 4.9e-51 172.3 0.0 6.3e-51 171.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO19012.1 - 1.9e-18 67.0 0.0 3.3e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO19012.1 - 1.2e-13 50.6 0.0 1.5e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO19012.1 - 0.0001 21.8 0.1 0.0052 16.2 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 ETO19012.1 - 0.00029 20.7 0.0 0.00056 19.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 ETO19012.1 - 0.0012 18.9 0.0 0.0024 18.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 ETO19012.1 - 0.0033 16.5 0.1 0.0068 15.5 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 ETO19012.1 - 0.011 15.6 0.1 0.015 15.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 ETO19012.1 - 0.016 14.8 0.1 0.053 13.1 0.0 1.9 2 0 0 2 2 2 0 NACHT domain SRPRB PF09439.5 ETO19012.1 - 0.018 14.2 0.0 0.03 13.5 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 ETO19012.1 - 0.046 13.1 0.1 0.17 11.3 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 ETO19012.1 - 0.053 12.7 0.0 0.086 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 ETO19012.1 - 0.089 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 ETO19012.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Septin BSP_II PF05432.6 ETO19014.1 - 0.0099 15.1 21.4 0.0092 15.2 14.0 1.5 1 1 1 2 2 2 1 Bone sialoprotein II (BSP-II) EFF-AFF PF14884.1 ETO19014.1 - 0.04 11.9 1.3 0.05 11.6 0.9 1.3 1 1 0 1 1 1 0 Type I membrane glycoproteins cell-cell fusogen Hid1 PF12722.2 ETO19014.1 - 0.044 11.4 4.1 0.038 11.6 2.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Myc_N PF01056.13 ETO19014.1 - 0.1 11.7 6.8 0.17 11.0 4.7 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Pox_Ag35 PF03286.9 ETO19014.1 - 0.11 12.0 11.6 0.21 11.0 8.0 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CRT10 PF08728.5 ETO19014.1 - 0.15 10.0 4.9 0.16 9.9 3.4 1.1 1 0 0 1 1 1 0 CRT10 Ycf1 PF05758.7 ETO19014.1 - 0.39 8.3 6.0 0.38 8.4 4.2 1.0 1 0 0 1 1 1 0 Ycf1 DDRGK PF09756.4 ETO19014.1 - 0.62 9.4 15.7 0.88 8.9 10.9 1.1 1 0 0 1 1 1 0 DDRGK domain CDC45 PF02724.9 ETO19014.1 - 0.91 7.4 11.4 1 7.3 7.9 1.2 1 0 0 1 1 1 0 CDC45-like protein FYDLN_acid PF09538.5 ETO19014.1 - 2.3 8.8 14.2 0.22 12.1 5.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) PGA2 PF07543.7 ETO19014.1 - 3.9 7.2 16.5 2 8.1 8.2 2.5 3 0 0 3 3 3 0 Protein trafficking PGA2 VID27 PF08553.5 ETO19014.1 - 5.2 5.1 18.4 0.84 7.7 10.1 1.5 2 0 0 2 2 2 0 VID27 cytoplasmic protein HSP90 PF00183.13 ETO19014.1 - 5.7 5.2 16.5 8.8 4.5 11.5 1.2 1 0 0 1 1 1 0 Hsp90 protein Menin PF05053.8 ETO19014.1 - 7.5 4.5 9.6 10 4.1 6.7 1.1 1 0 0 1 1 1 0 Menin MMPL PF03176.10 ETO19015.1 - 3e-28 98.5 3.0 2.8e-25 88.7 2.0 2.2 1 1 0 1 1 1 1 MMPL family DUF1625 PF07787.7 ETO19015.1 - 5.1 6.2 7.2 0.27 10.4 1.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1625) SNF2_N PF00176.18 ETO19016.1 - 4.4e-31 107.7 0.0 6.8e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETO19016.1 - 2e-11 43.6 0.2 1.2e-10 41.0 0.0 2.5 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETO19016.1 - 7.9e-10 38.8 1.3 1.1e-07 31.9 0.0 3.4 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit AAA_11 PF13086.1 ETO19016.1 - 0.0078 15.8 0.9 0.059 12.9 0.1 2.4 3 0 0 3 3 3 1 AAA domain YgbB PF02542.11 ETO19016.1 - 0.059 13.1 0.1 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 YgbB family AAA_22 PF13401.1 ETO19016.1 - 0.092 12.8 0.0 2.4 8.2 0.0 2.9 2 1 0 2 2 2 0 AAA domain FCH PF00611.18 ETO19017.1 - 0.81 9.9 6.1 4.2 7.6 4.2 2.0 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain UT PF03253.9 ETO19019.1 - 7.8e-29 100.5 9.0 9e-29 100.3 6.2 1.0 1 0 0 1 1 1 1 Urea transporter EmrE PF13536.1 ETO19019.1 - 1.8 8.7 15.6 0.08 13.1 3.5 2.2 1 1 1 2 2 2 0 Multidrug resistance efflux transporter DNA_pol_viral_N PF00242.12 ETO19020.1 - 4.8 6.1 9.0 5.7 5.8 6.2 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF908 PF06012.7 ETO19021.1 - 4.4 6.5 9.8 3.8 6.7 6.0 1.5 1 1 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF4654 PF15547.1 ETO19021.1 - 7 6.9 6.2 0.92 9.8 0.7 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4654) ThiS PF02597.15 ETO19024.1 - 0.017 15.4 0.7 0.04 14.3 0.5 1.7 1 0 0 1 1 1 0 ThiS family TRAP-gamma PF07074.7 ETO19024.1 - 0.027 14.0 2.1 0.09 12.2 1.5 1.9 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) PH PF00169.24 ETO19024.1 - 0.036 14.2 0.4 0.036 14.2 0.3 2.7 2 0 0 2 2 2 0 PH domain COMP PF11598.3 ETO19024.1 - 0.051 13.6 3.6 1.7 8.7 0.0 2.6 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein Lectin_N PF03954.9 ETO19024.1 - 0.11 11.9 1.6 0.25 10.7 0.5 2.2 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain UCH PF00443.24 ETO19025.1 - 2.3e-31 108.8 0.9 4.1e-31 108.0 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO19025.1 - 5.5e-21 75.2 0.4 9.6e-20 71.1 0.1 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 ETO19025.1 - 7.1e-10 39.1 0.4 7.1e-10 39.1 0.2 2.6 3 1 0 3 3 3 1 DUSP domain Pox_A6 PF04924.7 ETO19025.1 - 0.055 12.2 0.8 0.09 11.5 0.1 1.6 2 0 0 2 2 2 0 Poxvirus A6 protein WD40 PF00400.27 ETO19028.1 - 3.9e-18 64.5 2.7 1.1e-06 28.2 0.0 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Synaptonemal_3 PF15191.1 ETO19029.1 - 0.0029 17.2 2.5 0.019 14.6 0.0 2.7 3 0 0 3 3 3 1 Synaptonemal complex central element protein 3 DUF4200 PF13863.1 ETO19029.1 - 0.0035 17.2 10.4 0.26 11.2 0.9 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4200) MbeD_MobD PF04899.7 ETO19029.1 - 0.0058 16.4 1.5 1.5 8.7 0.0 2.5 1 1 1 2 2 2 1 MbeD/MobD like DUF342 PF03961.8 ETO19029.1 - 0.0069 14.8 3.7 0.008 14.6 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) FlxA PF14282.1 ETO19029.1 - 0.0077 16.1 15.7 0.12 12.2 3.0 2.2 1 1 1 2 2 2 2 FlxA-like protein IncA PF04156.9 ETO19029.1 - 0.012 15.1 2.0 0.015 14.8 1.4 1.2 1 0 0 1 1 1 0 IncA protein Fib_alpha PF08702.5 ETO19029.1 - 0.018 15.1 8.1 0.018 15.1 5.6 1.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family HR1 PF02185.11 ETO19029.1 - 0.021 14.5 5.0 0.22 11.2 0.6 2.4 2 0 0 2 2 2 0 Hr1 repeat BLOC1_2 PF10046.4 ETO19029.1 - 0.021 14.9 8.5 0.12 12.5 1.8 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_2 PF07716.10 ETO19029.1 - 0.04 13.7 4.3 1.1 9.0 0.5 2.6 2 0 0 2 2 2 0 Basic region leucine zipper DUF1593 PF07632.6 ETO19029.1 - 0.041 13.1 0.6 0.057 12.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) DivIC PF04977.10 ETO19029.1 - 0.069 12.6 7.5 0.19 11.2 1.7 2.4 2 0 0 2 2 2 0 Septum formation initiator DUF4279 PF14106.1 ETO19029.1 - 0.078 12.8 1.9 0.25 11.2 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4279) Pollen_Ole_e_I PF01190.12 ETO19029.1 - 0.12 12.1 0.3 2.8 7.8 0.0 2.3 1 1 0 2 2 2 0 Pollen proteins Ole e I like Laminin_II PF06009.7 ETO19029.1 - 0.5 10.1 5.0 1.3 8.7 3.4 1.7 1 1 1 2 2 2 0 Laminin Domain II DUF4407 PF14362.1 ETO19029.1 - 0.63 8.9 4.4 1 8.2 3.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2205 PF10224.4 ETO19029.1 - 1.1 8.8 7.5 1.2 8.7 0.9 2.3 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) PspA_IM30 PF04012.7 ETO19029.1 - 1.2 8.4 6.4 0.85 8.9 0.3 2.3 1 1 0 2 2 2 0 PspA/IM30 family DUF3573 PF12097.3 ETO19029.1 - 1.4 7.4 11.0 2.5 6.5 2.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) FliD_N PF02465.13 ETO19029.1 - 2.8 8.3 5.2 4.4 7.7 0.5 2.2 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Tropomyosin_1 PF12718.2 ETO19029.1 - 4.5 7.1 9.8 8.4 6.2 2.4 2.2 1 1 1 2 2 2 0 Tropomyosin like SAM_1 PF00536.25 ETO19030.1 - 3.3e-07 30.3 0.7 5.4e-07 29.6 0.5 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO19030.1 - 1.9e-06 27.5 1.1 3.1e-06 26.9 0.7 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 ETO19030.1 - 2.5e-05 23.9 0.3 5.3e-05 22.9 0.2 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain RhoGAP PF00620.22 ETO19031.1 - 4e-09 36.2 0.0 5.1e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain EF-hand_7 PF13499.1 ETO19032.1 - 2.1e-07 30.9 0.7 3.6e-07 30.2 0.5 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO19032.1 - 2.7e-05 23.6 0.9 0.14 12.1 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 ETO19032.1 - 4.9e-05 22.3 1.3 0.082 12.2 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_10 PF14788.1 ETO19032.1 - 0.033 13.8 0.1 0.071 12.7 0.1 1.5 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.1 ETO19032.1 - 0.04 13.5 0.5 0.22 11.1 0.2 2.1 1 1 1 2 2 2 0 EF-hand domain pair p25-alpha PF05517.7 ETO19032.1 - 0.16 12.2 4.3 0.2 11.8 0.1 2.1 2 0 0 2 2 2 0 p25-alpha Mucin PF01456.12 ETO19032.1 - 0.28 10.9 34.3 0.4 10.4 23.8 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Tir_receptor_C PF07489.6 ETO19032.1 - 0.7 9.6 13.3 0.98 9.1 9.2 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus TPR_12 PF13424.1 ETO19033.1 - 1.3e-06 28.2 2.1 0.0046 16.8 0.1 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO19033.1 - 0.0001 21.9 7.1 0.012 15.5 0.4 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO19033.1 - 0.019 15.5 0.6 2.5 8.9 0.0 3.0 2 1 0 3 3 3 0 Tetratricopeptide repeat UVR PF02151.14 ETO19033.1 - 0.051 13.1 3.5 0.16 11.5 0.2 2.5 2 0 0 2 2 2 0 UvrB/uvrC motif TPR_8 PF13181.1 ETO19033.1 - 0.076 12.8 7.8 0.27 11.1 0.4 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat BsuBI_PstI_RE PF06616.6 ETO19033.1 - 0.086 11.6 0.2 0.098 11.4 0.1 1.1 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease C-terminus Secretin_N_2 PF07655.8 ETO19034.1 - 6.6 7.1 23.4 11 6.4 16.2 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Macoilin PF09726.4 ETO19035.1 - 5.2 5.2 16.6 6.7 4.8 11.5 1.1 1 0 0 1 1 1 0 Transmembrane protein TRAP_alpha PF03896.11 ETO19035.1 - 6.7 5.6 10.8 0.67 8.8 1.7 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.7 ETO19035.1 - 7.9 4.2 32.1 1.1 7.1 3.5 2.0 1 1 1 2 2 2 0 Nop14-like family BRCT PF00533.21 ETO19036.1 - 0.00016 21.7 2.2 0.0042 17.2 0.1 2.9 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Daxx PF03344.10 ETO19036.1 - 0.0044 15.5 13.9 0.0055 15.2 9.7 1.2 1 0 0 1 1 1 1 Daxx Family Mem_trans PF03547.13 ETO19036.1 - 0.26 9.5 0.9 0.3 9.3 0.6 1.2 1 0 0 1 1 1 0 Membrane transport protein SAPS PF04499.10 ETO19036.1 - 0.31 9.6 8.0 0.45 9.1 5.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TFIIF_alpha PF05793.7 ETO19036.1 - 0.41 8.9 25.0 0.62 8.3 17.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Peptidase_S64 PF08192.6 ETO19036.1 - 1.6 6.9 7.7 2 6.6 5.3 1.2 1 0 0 1 1 1 0 Peptidase family S64 FRG2 PF15315.1 ETO19036.1 - 1.8 8.4 17.2 3.6 7.5 11.9 1.4 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 TAF4 PF05236.9 ETO19036.1 - 3.1 7.0 16.3 5 6.3 11.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF2890 PF11081.3 ETO19036.1 - 4.4 7.3 16.9 8.5 6.3 11.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) RUN PF02759.14 ETO19038.1 - 4.6e-07 29.6 0.0 1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 RUN domain Nop14 PF04147.7 ETO19038.1 - 0.011 13.7 24.1 0.015 13.3 16.7 1.2 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 ETO19038.1 - 0.011 14.2 34.7 0.018 13.5 24.0 1.2 1 0 0 1 1 1 0 Daxx Family Hid1 PF12722.2 ETO19038.1 - 0.28 8.8 21.1 0.35 8.5 14.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Utp14 PF04615.8 ETO19038.1 - 0.34 9.0 30.3 0.43 8.6 21.0 1.2 1 0 0 1 1 1 0 Utp14 protein BUD22 PF09073.5 ETO19038.1 - 5.1 6.0 33.5 8.2 5.3 23.2 1.2 1 0 0 1 1 1 0 BUD22 DUF605 PF04652.11 ETO19038.1 - 8.4 5.6 29.7 11 5.2 20.6 1.1 1 0 0 1 1 1 0 Vta1 like DUF262 PF03235.9 ETO19040.1 - 4.8 7.0 13.5 24 4.7 9.4 1.9 1 1 0 1 1 1 0 Protein of unknown function DUF262 Sec3_C_2 PF15278.1 ETO19041.1 - 0.003 17.6 2.6 0.059 13.5 1.0 2.2 1 1 2 3 3 3 1 Sec3 exocyst complex subunit Spore_III_AF PF09581.5 ETO19041.1 - 0.0088 15.9 2.0 0.011 15.6 1.4 1.1 1 0 0 1 1 1 1 Stage III sporulation protein AF (Spore_III_AF) Cas_CT1975 PF09344.5 ETO19041.1 - 0.028 13.8 0.2 0.033 13.5 0.1 1.0 1 0 0 1 1 1 0 CT1975-like protein LMBR1 PF04791.11 ETO19041.1 - 0.061 11.8 0.3 0.074 11.6 0.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein HHH_8 PF14716.1 ETO19041.1 - 0.09 12.9 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF2407_C PF13373.1 ETO19041.1 - 0.1 12.5 0.4 0.14 12.0 0.3 1.1 1 0 0 1 1 1 0 DUF2407 C-terminal domain ATG16 PF08614.6 ETO19041.1 - 0.12 12.1 6.1 0.18 11.5 4.3 1.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.7 ETO19041.1 - 0.13 12.0 10.2 0.19 11.4 7.1 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PSP1 PF04468.7 ETO19041.1 - 0.15 12.0 0.8 0.29 11.1 0.6 1.5 1 0 0 1 1 1 0 PSP1 C-terminal conserved region WD40 PF00400.27 ETO19043.1 - 2.5e-26 90.5 10.3 3e-10 39.5 0.1 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 ETO19043.1 - 0.0047 16.6 0.1 2.3 8.0 0.0 3.6 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.6 ETO19043.1 - 0.029 14.0 1.1 0.23 11.1 0.1 2.7 2 2 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO19043.1 - 0.062 11.5 0.1 2.3 6.4 0.0 2.6 3 0 0 3 3 3 0 Cytochrome D1 heme domain B_lectin PF01453.19 ETO19044.1 - 2.8e-08 33.6 0.5 0.0002 21.1 0.0 2.5 2 0 0 2 2 2 2 D-mannose binding lectin TLV_coat PF00429.14 ETO19044.1 - 0.055 11.9 1.0 0.12 10.7 0.6 1.5 2 0 0 2 2 2 0 ENV polyprotein (coat polyprotein) ubiquitin PF00240.18 ETO19045.1 - 0.018 14.3 0.1 4.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin family Ubiquitin_2 PF14560.1 ETO19045.1 - 0.028 14.6 0.0 9.2 6.6 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain TATR PF03430.8 ETO19048.1 - 0.32 9.5 27.3 0.5 8.9 19.0 1.3 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Dapper PF15268.1 ETO19048.1 - 9.3 4.9 50.8 12 4.4 35.2 1.0 1 0 0 1 1 1 0 Dapper Nucleoporin_N PF08801.6 ETO19049.1 - 0.016 14.0 0.1 0.024 13.3 0.1 1.2 1 0 0 1 1 1 0 Nup133 N terminal like WD40 PF00400.27 ETO19049.1 - 0.018 14.9 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 WD domain, G-beta repeat 7TM_transglut PF14402.1 ETO19049.1 - 0.1 11.5 0.8 0.16 10.9 0.3 1.4 2 0 0 2 2 2 0 7 transmembrane helices usually fused to an inactive transglutaminase Sporozoite_P67 PF05642.6 ETO19050.1 - 0.0043 14.9 5.6 0.0053 14.7 3.9 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Cauli_DNA-bind PF03310.8 ETO19050.1 - 0.038 13.8 0.1 0.08 12.7 0.1 1.6 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein Baculo_PEP_C PF04513.7 ETO19050.1 - 0.12 12.2 0.1 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF632 PF04782.7 ETO19050.1 - 0.39 9.7 2.9 0.81 8.7 2.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF632) NPR3 PF03666.8 ETO19050.1 - 1.2 7.5 8.0 0.31 9.5 0.0 2.0 1 1 1 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Macoilin PF09726.4 ETO19050.1 - 6.9 4.8 10.5 8.6 4.4 7.3 1.2 1 0 0 1 1 1 0 Transmembrane protein CorA PF01544.13 ETO19051.1 - 0.037 13.0 5.1 0.049 12.6 3.5 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein MbeD_MobD PF04899.7 ETO19051.1 - 0.11 12.3 9.9 0.042 13.7 3.0 2.3 1 1 1 2 2 2 0 MbeD/MobD like tRNA_NucTransf2 PF09249.6 ETO19051.1 - 0.45 10.4 2.5 2.6 7.9 0.1 2.3 2 1 0 2 2 2 0 tRNA nucleotidyltransferase, second domain BLVR PF06375.6 ETO19052.1 - 0.6 9.9 13.2 0.98 9.2 9.2 1.5 1 1 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Uds1 PF15456.1 ETO19052.1 - 1.7 8.6 7.2 2.8 7.9 4.9 1.4 1 1 0 1 1 1 0 Up-regulated During Septation Nop14 PF04147.7 ETO19053.1 - 3.7e-05 21.8 23.0 4.1e-05 21.7 15.9 1.3 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 ETO19053.1 - 0.00028 19.5 25.7 0.00042 18.9 17.8 1.4 1 0 0 1 1 1 1 Daxx Family CDC45 PF02724.9 ETO19053.1 - 0.0099 13.9 22.7 0.016 13.3 15.7 1.4 1 0 0 1 1 1 1 CDC45-like protein CENP-T PF15511.1 ETO19053.1 - 0.031 13.5 15.1 0.038 13.2 10.5 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T BUD22 PF09073.5 ETO19053.1 - 0.055 12.5 27.4 0.083 11.9 19.0 1.4 1 0 0 1 1 1 0 BUD22 DUF1510 PF07423.6 ETO19053.1 - 0.39 10.0 29.4 0.16 11.3 17.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Astro_capsid PF03115.9 ETO19053.1 - 3 5.9 16.8 3.9 5.6 11.7 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor SDA1 PF05285.7 ETO19053.1 - 9.8 5.3 39.6 1.3 8.2 23.9 1.9 2 0 0 2 2 2 0 SDA1 HUN PF08729.5 ETO19054.1 - 1.5e-08 34.3 0.2 1.5e-08 34.3 0.2 2.8 2 0 0 2 2 2 1 HPC2 and ubinuclein domain Pex14_N PF04695.8 ETO19054.1 - 3.9 7.5 13.5 0.21 11.6 5.2 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Tetraspannin PF00335.15 ETO19054.1 - 9.7 5.3 7.8 20 4.3 5.4 1.5 1 0 0 1 1 1 0 Tetraspanin family LGFP PF08310.6 ETO19055.1 - 0.03 13.9 0.0 0.058 13.0 0.0 1.5 1 0 0 1 1 1 0 LGFP repeat Vfa1 PF08432.5 ETO19055.1 - 8.3 6.3 20.5 0.67 9.9 10.1 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Kelch_6 PF13964.1 ETO19056.1 - 6.7e-10 38.7 2.4 0.016 15.3 0.0 5.0 4 1 1 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO19056.1 - 6e-07 28.9 1.2 0.054 13.0 0.0 4.1 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO19056.1 - 0.00062 19.4 1.5 0.019 14.7 0.0 3.8 4 1 1 5 5 5 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO19056.1 - 0.0012 18.5 1.8 0.75 9.6 0.0 4.5 5 0 0 5 5 5 1 Kelch motif Kelch_5 PF13854.1 ETO19056.1 - 0.0014 18.5 1.5 8 6.5 0.0 4.5 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.1 ETO19056.1 - 0.008 16.3 0.2 0.12 12.5 0.0 3.0 3 0 0 3 3 3 1 Galactose oxidase, central domain Peptidase_C14 PF00656.17 ETO19057.1 - 4e-07 29.9 0.7 9.2e-07 28.8 0.5 1.6 1 1 0 1 1 1 1 Caspase domain UCH PF00443.24 ETO19059.1 - 2.2e-07 30.2 6.4 6.6e-07 28.7 4.4 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Caldesmon PF02029.10 ETO19059.1 - 0.003 16.0 7.8 0.0039 15.6 5.4 1.1 1 0 0 1 1 1 1 Caldesmon UCH_1 PF13423.1 ETO19059.1 - 0.016 14.6 2.7 0.018 14.5 1.9 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Circo_capsid PF02443.10 ETO19059.1 - 0.017 14.4 1.9 0.02 14.2 1.3 1.1 1 0 0 1 1 1 0 Circovirus capsid protein Peptidase_C98 PF15499.1 ETO19059.1 - 0.095 11.9 1.1 0.11 11.7 0.8 1.1 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase ScpA_ScpB PF02616.9 ETO19059.1 - 0.14 11.6 2.9 0.15 11.6 2.0 1.3 1 0 0 1 1 1 0 ScpA/B protein Ipi1_N PF12333.3 ETO19059.1 - 0.18 11.8 0.4 0.49 10.3 0.3 1.8 1 1 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation Spt5_N PF11942.3 ETO19059.1 - 0.18 12.4 7.2 0.25 12.0 5.0 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Adeno_E4 PF05385.6 ETO19059.1 - 0.28 11.1 2.7 0.41 10.6 1.9 1.3 1 0 0 1 1 1 0 Mastadenovirus early E4 13 kDa protein TT_ORF1 PF02956.9 ETO19059.1 - 0.46 8.8 6.9 0.53 8.6 4.8 1.1 1 0 0 1 1 1 0 TT viral orf 1 DUF3987 PF13148.1 ETO19059.1 - 1.1 7.7 4.9 1.3 7.4 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) PAPA-1 PF04795.7 ETO19059.1 - 1.3 9.7 13.4 1.9 9.2 9.3 1.2 1 0 0 1 1 1 0 PAPA-1-like conserved region Rota_VP2 PF05087.7 ETO19059.1 - 2.8 5.7 5.1 3.1 5.6 3.5 1.0 1 0 0 1 1 1 0 Rotavirus VP2 protein Cag12 PF13117.1 ETO19060.1 - 0.24 11.3 0.1 0.24 11.3 0.1 2.1 2 1 0 2 2 2 0 Cag pathogenicity island protein Cag12 Mnd1 PF03962.10 ETO19060.1 - 4.7 6.8 13.3 6.6 6.3 9.2 1.2 1 0 0 1 1 1 0 Mnd1 family RGS PF00615.14 ETO19061.1 - 0.0023 18.0 4.3 0.014 15.5 3.1 1.8 1 1 0 1 1 1 1 Regulator of G protein signaling domain DNA_pol3_a_NII PF11490.3 ETO19061.1 - 0.13 11.8 4.7 0.19 11.3 3.3 1.2 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II TSA PF03249.8 ETO19061.1 - 9.3 4.6 7.4 11 4.3 5.1 1.1 1 0 0 1 1 1 0 Type specific antigen Neur_chan_LBD PF02931.18 ETO19062.1 - 0.0001 21.5 0.4 0.0001 21.5 0.3 1.4 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain STAT_int PF02865.12 ETO19064.1 - 0.48 10.3 5.3 0.13 12.2 0.4 2.4 2 1 1 3 3 3 0 STAT protein, protein interaction domain DUF4484 PF14831.1 ETO19064.1 - 2.3 8.3 19.0 0.85 9.6 10.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) DUF2345 PF10106.4 ETO19065.1 - 0.06 12.9 0.5 0.65 9.5 0.0 2.5 2 2 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2345) Raptor_N PF14538.1 ETO19068.1 - 2.3e-28 98.9 0.6 3.3e-28 98.4 0.0 1.5 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain Peptidase_C14 PF00656.17 ETO19068.1 - 0.023 14.4 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Caspase domain DUF3546 PF12066.3 ETO19068.1 - 0.03 14.3 0.3 0.048 13.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3546) fn3 PF00041.16 ETO19069.1 - 0.0012 18.9 0.8 0.0078 16.3 0.0 2.4 2 0 0 2 2 2 1 Fibronectin type III domain CP2 PF04516.10 ETO19069.1 - 0.0053 15.8 1.0 0.0085 15.1 0.7 1.2 1 0 0 1 1 1 1 CP2 transcription factor Glycohydro_20b2 PF14845.1 ETO19069.1 - 0.16 12.6 1.8 0.27 11.8 1.2 1.4 1 0 0 1 1 1 0 beta-acetyl hexosaminidase like NAD_binding_6 PF08030.7 ETO19071.1 - 0.00075 19.4 0.1 0.052 13.4 0.0 2.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain AAA_22 PF13401.1 ETO19072.1 - 7.4e-05 22.8 0.0 0.00034 20.7 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 ETO19072.1 - 0.00011 22.1 0.0 0.00054 19.8 0.0 2.3 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 ETO19072.1 - 0.0014 18.3 0.0 0.03 14.0 0.0 2.7 1 1 0 2 2 2 1 Archaeal ATPase IstB_IS21 PF01695.12 ETO19072.1 - 0.019 14.3 0.0 0.063 12.6 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_16 PF13191.1 ETO19072.1 - 0.034 14.1 0.1 0.63 9.9 0.0 2.3 1 1 1 2 2 2 0 AAA ATPase domain CPT PF07931.7 ETO19072.1 - 0.058 13.0 0.2 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein KdpD PF02702.12 ETO19072.1 - 0.1 11.7 0.6 4.3 6.4 0.0 3.1 3 0 0 3 3 3 0 Osmosensitive K+ channel His kinase sensor domain Enkurin PF13864.1 ETO19072.1 - 0.65 10.2 5.1 21 5.3 0.8 3.3 3 0 0 3 3 3 0 Calmodulin-binding Integrase_DNA PF02920.10 ETO19073.1 - 0.024 14.0 0.2 0.077 12.4 0.0 1.9 2 0 0 2 2 2 0 DNA binding domain of tn916 integrase FANCI_S3 PF14677.1 ETO19073.1 - 0.066 12.5 1.9 4 6.7 0.1 2.8 3 0 0 3 3 3 0 FANCI solenoid 3 Apc13p PF05839.6 ETO19073.1 - 0.11 12.4 0.1 0.56 10.2 0.0 2.0 2 0 0 2 2 2 0 Apc13p protein Glyco_hydro_2 PF00703.16 ETO19073.1 - 0.3 11.5 5.1 0.083 13.3 0.9 1.9 2 0 0 2 2 2 0 Glycosyl hydrolases family 2 CBM_3 PF00942.13 ETO19073.1 - 2.4 8.2 0.0 2.4 8.2 0.0 2.9 3 0 0 3 3 3 0 Cellulose binding domain WD40 PF00400.27 ETO19075.1 - 0.00018 21.2 0.3 0.00058 19.6 0.1 2.1 2 0 0 2 2 2 1 WD domain, G-beta repeat GP46 PF07409.7 ETO19075.1 - 0.034 13.4 0.0 0.08 12.2 0.0 1.5 1 0 0 1 1 1 0 Phage protein GP46 O-antigen_lig PF13425.1 ETO19076.1 - 0.00062 19.7 0.6 0.0013 18.7 0.4 1.5 1 0 0 1 1 1 1 O-antigen ligase like membrane protein RCC1_2 PF13540.1 ETO19076.1 - 0.0058 16.2 0.7 0.0058 16.2 0.5 3.1 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat PH PF00169.24 ETO19076.1 - 0.022 14.9 1.7 0.06 13.5 0.2 2.5 2 0 0 2 2 2 0 PH domain 7TM-7TMR_HD PF07698.6 ETO19076.1 - 0.11 11.9 2.3 0.19 11.1 1.6 1.3 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase RCC1 PF00415.13 ETO19076.1 - 0.41 10.8 7.3 15 5.9 0.0 5.0 5 1 0 5 5 5 0 Regulator of chromosome condensation (RCC1) repeat DUF2079 PF09852.4 ETO19076.1 - 1.5 7.4 4.7 4.5 5.8 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2079) DUF3753 PF12575.3 ETO19076.1 - 5 7.0 10.5 28 4.5 7.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3753) Trp_dioxygenase PF03301.8 ETO19078.1 - 5.9e-37 127.5 1.9 5.5e-22 78.3 0.1 2.1 2 0 0 2 2 2 2 Tryptophan 2,3-dioxygenase TRP PF06011.7 ETO19079.1 - 0.044 12.3 0.1 0.044 12.3 0.1 1.4 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel Zn_clus PF00172.13 ETO19080.1 - 5.3 7.0 9.9 6.6 6.7 4.5 2.6 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain UCH PF00443.24 ETO19081.1 - 0.24 10.4 4.5 0.25 10.4 3.1 1.0 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF3496 PF12001.3 ETO19081.1 - 0.37 11.0 2.5 0.49 10.6 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) IU_nuc_hydro PF01156.14 ETO19084.1 - 7.5e-16 58.2 0.0 8.8e-16 58.0 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase PH PF00169.24 ETO19085.1 - 0.0001 22.4 0.0 0.0018 18.4 0.0 2.3 2 0 0 2 2 2 1 PH domain RhoGEF PF00621.15 ETO19085.1 - 0.025 14.4 0.1 0.051 13.4 0.1 1.5 1 0 0 1 1 1 0 RhoGEF domain TPR_12 PF13424.1 ETO19086.1 - 0.0001 22.1 1.3 0.0024 17.7 0.2 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat GDE_C PF06202.9 ETO19086.1 - 0.077 11.6 0.1 0.094 11.4 0.0 1.2 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Nha1_C PF08619.5 ETO19087.1 - 1.2e-06 28.1 8.2 1.7e-06 27.6 5.7 1.3 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus DUF3733 PF12534.3 ETO19087.1 - 0.085 12.1 1.4 0.18 11.1 1.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat containing protein 8 Herpes_LMP1 PF05297.6 ETO19087.1 - 0.27 10.1 11.8 0.43 9.4 8.2 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DAGK_acc PF00609.14 ETO19088.1 - 6.8e-34 117.3 0.1 1.4e-33 116.3 0.0 1.5 2 1 0 2 2 2 1 Diacylglycerol kinase accessory domain Pkinase PF00069.20 ETO19089.1 - 1.3e-05 24.5 0.0 2.8e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Mucin PF01456.12 ETO19089.1 - 2.6 7.8 30.4 0.22 11.2 11.4 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein WD40 PF00400.27 ETO19090.1 - 9e-14 50.7 10.2 9.3e-06 25.3 0.1 4.5 3 1 0 3 3 3 3 WD domain, G-beta repeat Prion PF00377.13 ETO19090.1 - 0.061 13.0 0.4 0.49 10.1 0.0 2.1 2 0 0 2 2 2 0 Prion/Doppel alpha-helical domain GSDH PF07995.6 ETO19090.1 - 0.069 12.2 0.3 0.73 8.8 0.0 2.2 2 0 0 2 2 2 0 Glucose / Sorbosone dehydrogenase WD40 PF00400.27 ETO19092.1 - 1.8e-53 176.6 3.7 9.6e-11 41.1 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO19092.1 - 4.9e-14 52.4 0.1 3.6e-07 30.0 0.0 3.2 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO19092.1 - 4.4e-07 28.4 0.2 0.21 9.6 0.0 3.4 1 1 0 3 3 3 3 Nucleoporin Nup120/160 PD40 PF07676.7 ETO19092.1 - 1.2e-06 28.0 7.9 0.73 9.5 0.0 6.8 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 ETO19092.1 - 3.9e-06 25.7 0.0 1.3 7.5 0.0 4.9 1 1 4 6 6 6 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region PQQ_2 PF13360.1 ETO19092.1 - 1.6e-05 24.5 0.4 0.0013 18.2 0.3 2.9 1 1 0 1 1 1 1 PQQ-like domain Coatomer_WDAD PF04053.9 ETO19092.1 - 0.00011 21.1 0.1 0.0056 15.5 0.0 2.5 1 1 2 3 3 3 1 Coatomer WD associated region Cytochrom_D1 PF02239.11 ETO19092.1 - 0.00035 18.9 0.1 0.19 9.9 0.0 2.8 1 1 3 4 4 4 4 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO19092.1 - 0.00038 19.6 3.4 1.6 7.7 0.2 4.5 2 1 3 5 5 5 2 Neuroblastoma-amplified sequence, N terminal B_lectin PF01453.19 ETO19092.1 - 0.003 17.4 0.4 0.34 10.7 0.0 3.3 2 1 2 4 4 4 1 D-mannose binding lectin Resistin PF06954.6 ETO19092.1 - 0.0083 16.3 0.1 0.16 12.2 0.1 2.7 3 0 0 3 3 3 1 Resistin GSDH PF07995.6 ETO19092.1 - 0.029 13.4 0.0 12 4.9 0.0 3.5 3 1 0 4 4 4 0 Glucose / Sorbosone dehydrogenase Gmad1 PF10647.4 ETO19092.1 - 0.061 12.7 0.0 0.93 8.8 0.0 2.2 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain DUF1652 PF07865.6 ETO19092.1 - 0.065 12.8 0.0 22 4.7 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1652) AdoHcyase_NAD PF00670.16 ETO19093.1 - 0.17 11.7 0.8 0.69 9.7 0.1 2.0 1 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ubiquitin PF00240.18 ETO19095.1 - 1.5e-06 27.4 0.1 3.1e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 ETO19095.1 - 0.0025 17.4 0.4 0.015 14.9 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like WD40 PF00400.27 ETO19097.1 - 7.7e-34 114.3 12.4 6.4e-12 44.8 0.2 4.0 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO19097.1 - 7.2e-05 21.1 2.3 0.02 13.0 0.3 2.9 1 1 2 3 3 3 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO19097.1 - 0.0048 16.6 0.5 0.044 13.5 0.1 2.3 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Peptidase_C14 PF00656.17 ETO19098.1 - 2.7e-05 23.9 0.4 4.8e-05 23.1 0.3 1.3 1 0 0 1 1 1 1 Caspase domain DUF1643 PF07799.7 ETO19098.1 - 0.017 14.8 0.1 0.18 11.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1643) fn3 PF00041.16 ETO19099.1 - 4.1e-07 30.0 0.0 2e-05 24.6 0.0 2.4 2 0 0 2 2 2 1 Fibronectin type III domain DUF1510 PF07423.6 ETO19099.1 - 0.00087 18.7 12.5 0.002 17.5 6.5 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1510) TLP-20 PF06088.6 ETO19099.1 - 0.023 14.3 2.6 0.033 13.8 1.8 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) AF-4 PF05110.8 ETO19099.1 - 0.025 12.4 14.2 0.03 12.2 9.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Zip PF02535.17 ETO19099.1 - 0.042 12.8 0.0 0.057 12.4 0.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SID-1_RNA_chan PF13965.1 ETO19099.1 - 0.065 11.3 0.3 0.078 11.1 0.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CDC45 PF02724.9 ETO19099.1 - 0.28 9.1 12.8 0.34 8.9 8.9 1.1 1 0 0 1 1 1 0 CDC45-like protein GEMIN8 PF15348.1 ETO19099.1 - 0.38 10.7 6.5 0.61 10.1 4.5 1.3 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 FAM176 PF14851.1 ETO19099.1 - 0.66 9.6 8.2 1.3 8.7 5.7 1.4 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.7 ETO19099.1 - 0.69 7.7 14.2 0.84 7.4 9.8 1.0 1 0 0 1 1 1 0 Nop14-like family FLO_LFY PF01698.11 ETO19099.1 - 0.73 8.6 6.0 0.94 8.2 4.2 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Sigma70_ner PF04546.8 ETO19099.1 - 0.79 9.3 9.6 1.2 8.7 6.6 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Vfa1 PF08432.5 ETO19099.1 - 1.3 9.0 16.5 1.7 8.5 11.4 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RXT2_N PF08595.6 ETO19099.1 - 1.5 8.6 7.0 2.5 7.8 4.9 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF4614 PF15391.1 ETO19099.1 - 2.7 7.7 8.5 3.7 7.2 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) NPR3 PF03666.8 ETO19099.1 - 8.3 4.8 10.1 11 4.4 7.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 AAA PF00004.24 ETO19100.1 - 2.7e-53 179.6 0.1 1.2e-40 138.7 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 ETO19100.1 - 6.4e-08 31.7 0.0 0.0091 14.7 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_22 PF13401.1 ETO19100.1 - 2.9e-07 30.6 2.0 0.0022 18.1 0.7 4.3 2 2 0 2 2 2 1 AAA domain AAA_2 PF07724.9 ETO19100.1 - 1e-06 28.7 0.1 4.5e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 ETO19100.1 - 1.2e-06 28.6 0.2 0.00046 20.2 0.0 3.4 3 1 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.12 ETO19100.1 - 6.7e-06 25.6 0.0 0.0081 15.5 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_17 PF13207.1 ETO19100.1 - 2.2e-05 25.2 0.2 0.11 13.2 0.1 3.3 2 2 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 ETO19100.1 - 8.9e-05 22.6 0.0 0.11 12.7 0.0 3.0 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.9 ETO19100.1 - 0.00012 21.8 0.0 0.0014 18.3 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 ETO19100.1 - 0.00013 21.6 1.5 0.0048 16.6 0.0 3.6 5 0 0 5 5 5 1 Part of AAA domain AAA_18 PF13238.1 ETO19100.1 - 0.00017 21.8 0.0 0.023 15.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 ETO19100.1 - 0.00033 19.8 0.7 0.19 10.8 0.1 3.1 3 0 0 3 3 3 1 KaiC AAA_25 PF13481.1 ETO19100.1 - 0.00052 19.4 1.0 0.26 10.6 0.0 3.7 2 2 1 3 3 3 1 AAA domain Mg_chelatase PF01078.16 ETO19100.1 - 0.00055 19.1 0.0 0.0024 17.0 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 ETO19100.1 - 0.0018 18.6 0.2 0.057 13.7 0.1 3.2 3 1 0 3 3 3 1 ABC transporter AAA_33 PF13671.1 ETO19100.1 - 0.0064 16.3 0.0 0.15 11.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain Molydop_binding PF01568.16 ETO19100.1 - 0.0081 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain UPF0079 PF02367.12 ETO19100.1 - 0.0082 15.7 0.4 1.8 8.1 0.0 2.8 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 IPT PF01745.11 ETO19100.1 - 0.011 14.9 0.8 1.1 8.3 0.1 3.0 3 0 0 3 3 3 0 Isopentenyl transferase RuvB_N PF05496.7 ETO19100.1 - 0.011 14.7 0.0 0.11 11.5 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 ETO19100.1 - 0.013 15.1 0.0 1.3 8.6 0.0 3.2 2 1 0 2 2 2 0 NACHT domain AAA_24 PF13479.1 ETO19100.1 - 0.013 15.0 0.8 0.037 13.6 0.2 1.9 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 ETO19100.1 - 0.026 13.9 0.0 0.7 9.3 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Beta_helix PF13229.1 ETO19101.1 - 0.013 15.2 8.3 0.018 14.7 5.7 1.2 1 0 0 1 1 1 0 Right handed beta helix region DUF2688 PF10892.3 ETO19101.1 - 0.16 11.6 0.5 2.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) NosD PF05048.8 ETO19102.1 - 2e-30 105.7 50.0 1.6e-26 92.8 29.5 3.1 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.1 ETO19102.1 - 1.2e-09 38.1 63.0 8.6e-05 22.3 34.8 3.6 1 1 2 3 3 3 2 Right handed beta helix region TPR_12 PF13424.1 ETO19103.1 - 7.1e-118 384.7 37.1 2.7e-21 75.2 0.1 6.3 3 2 4 7 7 7 7 Tetratricopeptide repeat TPR_11 PF13414.1 ETO19103.1 - 4.6e-75 247.2 72.1 3.6e-14 52.1 1.8 6.9 1 1 8 9 9 9 9 TPR repeat TPR_10 PF13374.1 ETO19103.1 - 1.4e-58 193.2 0.0 3e-06 26.9 0.0 10.0 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_1 PF00515.23 ETO19103.1 - 2e-55 182.2 53.3 3.9e-08 32.5 3.6 10.6 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 ETO19103.1 - 1.5e-48 158.8 40.5 5.7e-06 25.8 1.9 10.4 10 1 0 10 10 10 10 Tetratricopeptide repeat TPR_7 PF13176.1 ETO19103.1 - 6e-48 156.8 18.3 6.2e-06 25.6 0.0 9.6 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.1 ETO19103.1 - 5.7e-34 113.3 54.0 0.00033 20.2 3.6 10.3 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_14 PF13428.1 ETO19103.1 - 3.4e-17 61.3 0.0 4 8.3 0.0 9.7 7 3 3 10 10 10 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO19103.1 - 1e-16 60.1 17.4 0.64 10.5 0.2 9.6 10 0 0 10 10 10 4 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO19103.1 - 1.1e-16 59.7 8.2 0.0061 15.7 0.0 8.6 8 1 0 8 8 8 4 SHNi-TPR TPR_16 PF13432.1 ETO19103.1 - 4.4e-16 59.0 0.4 0.072 13.7 0.0 6.7 3 2 3 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETO19103.1 - 9.3e-13 47.2 19.8 1.2 9.5 0.1 10.7 10 1 1 11 11 10 2 Tetratricopeptide repeat MIT PF04212.13 ETO19103.1 - 1.3e-08 34.6 30.4 0.42 10.5 0.0 9.2 8 2 1 9 9 9 4 MIT (microtubule interacting and transport) domain TPR_19 PF14559.1 ETO19103.1 - 6.5e-08 32.8 5.9 0.095 13.0 0.0 5.5 4 2 1 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO19103.1 - 1.6e-05 24.9 30.2 0.0017 18.4 2.4 5.3 2 2 5 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 ETO19103.1 - 0.0068 16.1 1.4 0.0068 16.1 1.0 6.8 9 0 0 9 9 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETO19103.1 - 0.022 14.6 0.4 1.3 8.9 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat SPO22 PF08631.5 ETO19103.1 - 0.12 11.3 6.8 0.22 10.5 0.0 3.4 2 1 1 3 3 3 0 Meiosis protein SPO22/ZIP4 like TPR_5 PF12688.2 ETO19103.1 - 0.15 12.1 3.8 24 4.9 0.0 4.7 3 2 3 6 6 6 0 Tetratrico peptide repeat mit_SMPDase PF14724.1 ETO19103.1 - 0.27 8.9 3.6 3 5.5 0.1 2.8 2 1 1 3 3 3 0 Mitochondrial-associated sphingomyelin phosphodiesterase RPN7 PF10602.4 ETO19103.1 - 0.4 10.0 22.5 9.6 5.5 0.3 6.2 3 3 2 6 6 6 0 26S proteasome subunit RPN7 Ubiq-assoc PF09145.5 ETO19103.1 - 0.43 10.4 16.8 4.7 7.1 0.0 7.1 6 2 3 9 9 9 0 Ubiquitin-associated ATP-synt_E_2 PF08112.6 ETO19103.1 - 4.2 7.5 5.9 18 5.5 0.0 4.6 7 0 0 7 7 5 0 ATP synthase epsilon subunit DUF962 PF06127.6 ETO19107.1 - 0.085 12.7 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF962) Colicin-DNase PF12639.2 ETO19107.1 - 0.43 10.8 3.2 0.46 10.7 0.1 2.4 2 2 0 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin Pneumovirus_M2 PF06436.6 ETO19107.1 - 1.5 8.0 6.6 0.12 11.5 1.2 1.7 2 0 0 2 2 2 0 Pneumovirus matrix protein 2 (M2) zf-SAP30 PF13866.1 ETO19107.1 - 5.1 6.8 9.2 1.6 8.4 0.6 2.8 3 0 0 3 3 3 0 SAP30 zinc-finger WD40 PF00400.27 ETO19108.1 - 4.6e-62 203.8 20.6 8.6e-12 44.4 0.2 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO19108.1 - 5.1e-13 48.0 6.0 0.00033 18.9 0.2 5.5 3 1 2 5 5 5 5 Nucleoporin Nup120/160 Herpes_UL52 PF03121.10 ETO19109.1 - 0.063 13.0 0.7 1.3 8.8 0.1 2.6 2 0 0 2 2 2 0 Herpesviridae UL52/UL70 DNA primase Acyl-CoA_dh_N PF02771.11 ETO19110.1 - 2.1e-24 86.2 0.0 4.5e-24 85.2 0.0 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain DUF997 PF06196.7 ETO19110.1 - 0.11 12.0 0.9 0.23 10.9 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF997) CAP_GLY PF01302.20 ETO19111.1 - 2e-07 30.6 0.0 3.3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain AATF-Che1 PF13339.1 ETO19111.1 - 0.001 19.2 4.6 0.0017 18.4 3.2 1.3 1 0 0 1 1 1 1 Apoptosis antagonizing transcription factor AAA_23 PF13476.1 ETO19111.1 - 0.0087 16.4 3.2 0.011 16.1 2.2 1.3 1 0 0 1 1 1 1 AAA domain EAP30 PF04157.11 ETO19111.1 - 0.0099 15.0 2.7 0.0099 15.0 1.8 1.9 3 0 0 3 3 3 1 EAP30/Vps36 family Phage_GPO PF05929.6 ETO19111.1 - 0.031 13.5 3.9 0.049 12.8 2.7 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF607 PF04678.8 ETO19111.1 - 0.37 10.7 2.5 0.56 10.1 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF607 DUF4315 PF14193.1 ETO19111.1 - 0.42 10.5 10.7 2.8 7.9 1.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4315) Kelch_5 PF13854.1 ETO19113.1 - 0.0024 17.7 0.2 1.4 8.9 0.1 2.2 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.1 ETO19113.1 - 0.016 15.3 0.5 1.1 9.5 0.1 2.2 1 1 1 2 2 2 0 Kelch motif Kelch_4 PF13418.1 ETO19113.1 - 0.039 13.7 0.1 0.47 10.2 0.0 2.0 1 1 1 2 2 2 0 Galactose oxidase, central domain Asp23 PF03780.8 ETO19113.1 - 0.056 13.7 0.3 0.077 13.2 0.2 1.2 1 0 0 1 1 1 0 Asp23 family Kelch_1 PF01344.20 ETO19113.1 - 0.13 11.8 1.2 1.1 8.8 0.0 2.4 2 1 0 2 2 2 0 Kelch motif Elf-1_N PF12310.3 ETO19113.1 - 0.35 10.8 2.2 0.6 10.0 1.4 1.4 1 1 0 1 1 1 0 Transcription factor protein N terminal WD40 PF00400.27 ETO19114.1 - 1.4e-24 85.0 4.0 2.1e-11 43.2 0.2 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO19114.1 - 0.0029 15.8 0.4 0.75 7.8 0.0 2.8 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Ank_2 PF12796.2 ETO19115.1 - 0.00072 19.8 0.1 0.0021 18.3 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Methyltransf_11 PF08241.7 ETO19117.1 - 5.6e-06 26.7 0.0 1.4e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETO19117.1 - 2.1e-05 24.7 0.1 7.3e-05 23.0 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETO19117.1 - 0.0033 17.1 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO19117.1 - 0.0087 16.6 0.0 0.018 15.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO19117.1 - 0.029 13.9 2.6 0.35 10.4 1.8 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 ETO19117.1 - 0.087 13.3 0.0 0.39 11.2 0.0 2.2 1 0 0 1 1 1 0 Methyltransferase domain DUF2817 PF10994.3 ETO19118.1 - 2.1e-44 152.0 0.0 6.4e-30 104.4 0.0 3.3 2 1 0 2 2 2 2 Protein of unknown function (DUF2817) DUF957 PF06117.6 ETO19118.1 - 0.2 11.2 1.7 1.5 8.4 0.2 2.2 2 0 0 2 2 2 0 Enterobacterial protein of unknown function (DUF957) EF-hand_1 PF00036.27 ETO19119.1 - 3.6e-08 32.1 0.4 2.3e-05 23.3 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 ETO19119.1 - 5.8e-08 32.7 0.3 1.5e-07 31.4 0.2 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO19119.1 - 1.1e-05 24.8 0.0 0.0048 16.6 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 ETO19119.1 - 4.8e-05 22.5 0.1 0.017 14.4 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 ETO19119.1 - 0.00076 19.0 0.8 0.0034 16.9 0.5 2.0 1 1 0 1 1 1 1 EF-hand domain pair DUF2652 PF10851.3 ETO19120.1 - 0.014 15.4 0.8 0.02 14.8 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2652) WD40 PF00400.27 ETO19121.1 - 9.5e-54 177.4 12.1 7.4e-14 51.0 0.2 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO19121.1 - 1.2e-10 40.1 2.9 0.034 12.3 0.1 4.1 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO19121.1 - 0.00084 17.7 0.1 0.14 10.3 0.0 2.6 1 1 2 3 3 3 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO19121.1 - 0.002 17.6 0.0 0.028 13.8 0.0 2.2 1 1 0 1 1 1 1 PQQ-like domain Mid2 PF04478.7 ETO19121.1 - 0.02 14.3 0.5 7 6.0 0.0 3.4 3 1 0 3 3 3 0 Mid2 like cell wall stress sensor BBS2_Mid PF14783.1 ETO19121.1 - 0.026 14.2 1.5 2.7 7.7 0.1 3.6 1 1 2 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Hira PF07569.6 ETO19121.1 - 0.074 12.2 1.1 1.6 7.9 0.1 3.2 2 1 1 4 4 4 0 TUP1-like enhancer of split PD40 PF07676.7 ETO19121.1 - 2.2 8.0 6.8 8 6.2 0.0 4.3 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 ETO19122.1 - 9.4e-09 34.8 0.2 2e-06 27.4 0.0 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF4131 PF13567.1 ETO19123.1 - 0.0082 15.5 0.1 0.015 14.6 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4131) EamA PF00892.15 ETO19123.1 - 0.017 15.1 1.1 0.034 14.2 0.1 1.9 2 0 0 2 2 2 0 EamA-like transporter family DUF998 PF06197.8 ETO19123.1 - 0.019 14.3 0.3 2.7 7.2 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF998) Ferric_reduct PF01794.14 ETO19123.1 - 0.023 14.7 0.1 0.043 13.8 0.1 1.5 1 1 0 1 1 1 0 Ferric reductase like transmembrane component Pox_P21 PF05313.7 ETO19123.1 - 0.13 11.5 1.1 0.22 10.7 0.0 1.9 3 0 0 3 3 3 0 Poxvirus P21 membrane protein DUF2644 PF10841.3 ETO19123.1 - 0.66 10.0 2.9 4.1 7.5 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2644) Mnd1 PF03962.10 ETO19124.1 - 2.1 7.9 14.6 0.49 10.0 3.3 2.7 2 0 0 2 2 2 0 Mnd1 family CRAL_TRIO PF00650.15 ETO19125.1 - 1.9e-10 40.4 0.0 2.5e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain UAA PF08449.6 ETO19128.1 - 0.059 12.2 0.8 0.083 11.7 0.6 1.2 1 0 0 1 1 1 0 UAA transporter family DUF2413 PF10310.4 ETO19128.1 - 1.2 7.8 15.7 0.27 10.0 4.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) zf-C2H2 PF00096.21 ETO19128.1 - 2 8.9 17.7 0.56 10.6 0.8 3.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type FYDLN_acid PF09538.5 ETO19128.1 - 2.4 8.7 8.5 2 9.0 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) DUF3449 PF11931.3 ETO19129.1 - 0.78 9.2 9.5 0.84 9.1 6.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) YqfQ PF14181.1 ETO19129.1 - 0.79 9.7 12.7 0.76 9.7 8.8 1.1 1 0 0 1 1 1 0 YqfQ-like protein HNOBA PF07701.9 ETO19129.1 - 1 8.5 5.4 1 8.5 3.7 1.1 1 0 0 1 1 1 0 Heme NO binding associated Zip PF02535.17 ETO19129.1 - 1.1 8.1 5.3 1.1 8.1 3.7 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Spb1_C PF07780.7 ETO19129.1 - 1.3 8.4 11.2 1.1 8.6 7.8 1.0 1 0 0 1 1 1 0 Spb1 C-terminal domain TraH_2 PF06871.6 ETO19129.1 - 1.4 8.3 7.4 1.5 8.2 5.1 1.0 1 0 0 1 1 1 0 TraH_2 RNA_pol_Rpc4 PF05132.9 ETO19129.1 - 2.1 8.3 10.8 2.1 8.3 7.5 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 XAP5 PF04921.9 ETO19129.1 - 2.3 7.7 12.3 2.2 7.8 8.5 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator NPR3 PF03666.8 ETO19129.1 - 2.3 6.6 5.0 2.2 6.7 3.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4589 PF15252.1 ETO19129.1 - 3.6 7.3 7.0 3.7 7.3 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) RRN3 PF05327.6 ETO19129.1 - 3.7 5.5 14.2 3.5 5.6 9.9 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sigma70_ner PF04546.8 ETO19129.1 - 3.8 7.0 23.0 4.3 6.9 15.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region SAPS PF04499.10 ETO19129.1 - 3.9 6.0 7.7 3.4 6.2 5.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Spore_coat_CotO PF14153.1 ETO19129.1 - 4.4 6.7 19.8 4.4 6.7 13.7 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF2052 PF09747.4 ETO19129.1 - 6 6.7 20.9 6.2 6.6 14.5 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF4628 PF15429.1 ETO19129.1 - 6.6 6.0 7.2 6.2 6.1 5.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) MYCBPAP PF14646.1 ETO19129.1 - 7 5.2 12.2 6.6 5.3 8.4 1.0 1 0 0 1 1 1 0 MYCBP-associated protein family DUF3306 PF11748.3 ETO19129.1 - 7.1 7.3 14.1 7.3 7.2 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Vfa1 PF08432.5 ETO19129.1 - 8.2 6.4 14.8 8.5 6.3 10.3 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Tim54 PF11711.3 ETO19129.1 - 8.4 4.8 14.0 8.6 4.8 9.7 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 AIF_C PF14721.1 ETO19129.1 - 9 6.5 7.1 9.4 6.4 4.9 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SpoIIP PF07454.6 ETO19129.1 - 9.1 5.3 9.6 8.9 5.3 6.7 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) PRP21_like_P PF12230.3 ETO19129.1 - 9.2 5.6 16.4 9.4 5.6 11.3 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein DEAD PF00270.24 ETO19130.1 - 6.1e-20 71.3 0.2 9.1e-20 70.8 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase eIF-4B PF06273.6 ETO19130.1 - 4.1 6.0 9.3 18 3.9 6.5 1.7 1 1 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B LRR_9 PF14580.1 ETO19131.1 - 0.013 15.0 0.5 0.019 14.5 0.4 1.3 1 0 0 1 1 1 0 Leucine-rich repeat Vmethyltransf_C PF08456.5 ETO19131.1 - 0.078 12.3 4.3 0.09 12.1 3.0 1.2 1 0 0 1 1 1 0 Viral methyltransferase C-terminal Dicty_REP PF05086.7 ETO19131.1 - 1.3 6.6 11.8 1.5 6.5 8.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 ETO19131.1 - 1.4 8.6 6.9 2 8.2 4.8 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2011 PF09428.5 ETO19131.1 - 1.7 8.4 16.8 3.6 7.4 11.6 1.6 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF2011) DUF2098 PF09871.4 ETO19131.1 - 2.2 8.2 16.0 0.51 10.3 0.4 2.5 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2098) Neur_chan_memb PF02932.11 ETO19131.1 - 2.7 7.7 4.8 3.4 7.4 3.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region APC_CDC26 PF10471.4 ETO19131.1 - 3.8 8.3 12.3 0.071 13.8 1.4 2.4 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 Cnd1_N PF12922.2 ETO19131.1 - 6.6 6.3 9.8 0.51 9.9 3.3 1.7 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term POX PF07526.6 ETO19131.1 - 8.1 6.6 9.3 1.1 9.4 2.6 2.0 2 0 0 2 2 2 0 Associated with HOX Myc_N PF01056.13 ETO19133.1 - 0.062 12.4 5.2 0.082 12.0 3.6 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF2507 PF10702.4 ETO19133.1 - 0.13 11.9 3.6 0.21 11.2 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2507) DDHD PF02862.12 ETO19133.1 - 0.43 10.3 10.0 0.49 10.1 7.0 1.2 1 0 0 1 1 1 0 DDHD domain p450 PF00067.17 ETO19133.1 - 0.59 8.5 6.9 0.7 8.3 4.6 1.3 1 1 0 1 1 1 0 Cytochrome P450 Ndc1_Nup PF09531.5 ETO19133.1 - 0.67 8.2 6.6 0.77 8.1 4.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2058 PF09831.4 ETO19133.1 - 1.1 9.1 14.8 1.7 8.5 10.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Spore_coat_CotO PF14153.1 ETO19133.1 - 1.4 8.3 17.1 1.6 8.1 11.9 1.2 1 0 0 1 1 1 0 Spore coat protein CotO NPR3 PF03666.8 ETO19133.1 - 1.4 7.3 10.0 1.7 7.0 7.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Phage_pRha PF09669.5 ETO19133.1 - 1.5 9.2 8.1 2.3 8.6 5.0 1.7 1 1 1 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) Band_3_cyto PF07565.8 ETO19133.1 - 2.5 7.5 6.7 2.8 7.3 4.7 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Hom_end_hint PF05203.11 ETO19133.1 - 3 7.4 7.8 3.4 7.3 5.4 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint Gag_spuma PF03276.9 ETO19133.1 - 3.1 6.0 5.4 3.6 5.7 3.7 1.0 1 0 0 1 1 1 0 Spumavirus gag protein IncA PF04156.9 ETO19133.1 - 4.6 6.7 7.6 5.3 6.5 5.3 1.2 1 0 0 1 1 1 0 IncA protein Neur_chan_memb PF02932.11 ETO19133.1 - 4.9 6.9 5.5 5.4 6.8 3.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TP53IP5 PF15331.1 ETO19133.1 - 6 6.7 15.2 7.4 6.4 10.5 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Cellulose_synt PF03552.9 ETO19133.1 - 8.7 4.4 8.1 9.4 4.3 5.6 1.1 1 0 0 1 1 1 0 Cellulose synthase PA26 PF04636.8 ETO19133.1 - 9.4 4.8 10.9 11 4.5 7.5 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CDC45 PF02724.9 ETO19134.1 - 0.013 13.6 16.5 0.013 13.5 11.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 ETO19134.1 - 0.035 12.0 23.3 0.034 12.0 16.2 1.0 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 ETO19134.1 - 0.056 12.6 12.3 0.06 12.5 8.5 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF2796 PF10986.3 ETO19134.1 - 0.13 12.2 7.0 0.16 11.9 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Nop25 PF09805.4 ETO19134.1 - 0.48 10.4 10.8 0.55 10.3 7.5 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF1510 PF07423.6 ETO19134.1 - 0.6 9.4 13.7 0.71 9.2 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FYDLN_acid PF09538.5 ETO19134.1 - 0.98 10.0 31.5 1.3 9.6 21.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) TRAP_alpha PF03896.11 ETO19134.1 - 2.2 7.2 15.9 2.3 7.1 11.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Packaging_FI PF14000.1 ETO19134.1 - 2.7 8.2 8.1 3.4 7.8 5.6 1.2 1 0 0 1 1 1 0 DNA packaging protein FI CDC27 PF09507.5 ETO19134.1 - 2.7 7.1 7.8 3.1 6.9 5.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Daxx PF03344.10 ETO19134.1 - 4.6 5.6 23.0 5.4 5.3 16.0 1.0 1 0 0 1 1 1 0 Daxx Family SAPS PF04499.10 ETO19134.1 - 5.4 5.5 5.9 5.3 5.5 4.1 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Osteopontin PF00865.13 ETO19134.1 - 6 6.0 31.6 7.1 5.7 21.9 1.3 1 0 0 1 1 1 0 Osteopontin IFT57 PF10498.4 ETO19134.1 - 7.8 5.1 10.2 8.2 5.0 7.1 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Rhabdo_ncap PF00945.13 ETO19134.1 - 9.1 4.7 6.8 11 4.4 4.7 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein TIMELESS_C PF05029.8 ETO19135.1 - 0.18 10.7 17.9 0.18 10.6 12.4 1.1 1 0 0 1 1 1 0 Timeless protein C terminal region C2 PF00168.25 ETO19138.1 - 2e-20 72.4 1.6 3e-20 71.8 0.8 1.6 2 0 0 2 2 2 1 C2 domain Ras PF00071.17 ETO19139.1 - 0.0002 20.7 1.1 0.00037 19.9 0.1 1.8 2 0 0 2 2 2 1 Ras family MAAL_C PF07476.6 ETO19139.1 - 0.045 12.6 0.1 0.061 12.2 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus GTP_EFTU PF00009.22 ETO19139.1 - 0.053 12.9 0.5 0.091 12.1 0.1 1.6 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF3099 PF11298.3 ETO19139.1 - 0.068 12.9 0.1 0.56 10.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) Molybdopterin PF00384.17 ETO19141.1 - 0.015 14.0 0.1 0.015 14.0 0.1 1.0 1 0 0 1 1 1 0 Molybdopterin oxidoreductase GAGA_bind PF06217.7 ETO19141.1 - 0.035 14.0 4.2 0.036 14.0 2.9 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Hid1 PF12722.2 ETO19141.1 - 0.055 11.1 5.6 0.055 11.1 3.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Merozoite_SPAM PF07133.6 ETO19141.1 - 0.064 13.1 17.3 0.088 12.7 12.0 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Prog_receptor PF02161.10 ETO19141.1 - 0.15 10.8 3.2 0.15 10.9 2.2 1.1 1 0 0 1 1 1 0 Progesterone receptor Bud13 PF09736.4 ETO19141.1 - 0.15 12.2 11.1 0.2 11.9 7.7 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex HSP90 PF00183.13 ETO19141.1 - 0.17 10.2 9.9 0.2 10.0 6.8 1.1 1 0 0 1 1 1 0 Hsp90 protein LAT PF15234.1 ETO19141.1 - 0.17 11.3 4.0 0.3 10.5 2.8 1.5 1 1 0 1 1 1 0 Linker for activation of T-cells Sporozoite_P67 PF05642.6 ETO19141.1 - 0.19 9.5 2.6 0.22 9.3 1.8 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BSP_II PF05432.6 ETO19141.1 - 0.23 10.7 13.1 0.28 10.4 9.1 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) SAPS PF04499.10 ETO19141.1 - 0.25 9.9 8.4 0.3 9.6 5.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF3807 PF12720.2 ETO19141.1 - 0.26 11.4 13.4 0.4 10.8 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF1510 PF07423.6 ETO19141.1 - 0.27 10.5 15.4 0.34 10.2 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Tom37_C PF11801.3 ETO19141.1 - 0.5 10.2 5.0 0.69 9.7 3.5 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain DHHW PF14286.1 ETO19141.1 - 0.52 9.5 4.9 0.59 9.3 3.4 1.1 1 0 0 1 1 1 0 DHHW protein Daxx PF03344.10 ETO19141.1 - 0.58 8.5 15.2 0.69 8.3 10.5 1.0 1 0 0 1 1 1 0 Daxx Family Neur_chan_memb PF02932.11 ETO19141.1 - 1.4 8.7 5.9 1.6 8.5 4.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ycf1 PF05758.7 ETO19141.1 - 1.5 6.4 10.5 1.6 6.3 7.3 1.0 1 0 0 1 1 1 0 Ycf1 Gti1_Pac2 PF09729.4 ETO19141.1 - 1.6 8.6 6.6 2.1 8.1 4.5 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family CDC45 PF02724.9 ETO19141.1 - 2 6.3 11.9 2.4 6.0 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4637 PF15470.1 ETO19141.1 - 3 7.4 14.3 4.3 6.9 9.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Peptidase_S64 PF08192.6 ETO19141.1 - 3.4 5.8 7.9 4.2 5.5 5.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 Presenilin PF01080.12 ETO19141.1 - 4.6 5.9 5.7 5.6 5.6 4.0 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.17 ETO19141.1 - 4.9 6.0 6.3 5.5 5.9 4.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DDHD PF02862.12 ETO19141.1 - 6.3 6.5 8.8 8.3 6.1 6.1 1.2 1 0 0 1 1 1 0 DDHD domain DUF4337 PF14235.1 ETO19141.1 - 6.8 6.5 7.2 12 5.7 5.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) VIT1 PF01988.14 ETO19141.1 - 8.3 5.8 5.6 10 5.5 3.9 1.1 1 0 0 1 1 1 0 VIT family Kelch_5 PF13854.1 ETO19144.1 - 4.6e-05 23.2 0.1 33 4.5 0.0 5.2 5 0 0 5 5 5 1 Kelch motif Kelch_6 PF13964.1 ETO19144.1 - 6.4e-05 22.9 2.2 0.46 10.7 0.1 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETO19144.1 - 0.002 17.8 0.7 0.1 12.4 0.0 3.7 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO19144.1 - 0.061 12.8 3.2 11 5.7 0.2 3.5 3 0 0 3 3 3 0 Kelch motif MORN PF02493.15 ETO19146.1 - 5.1e-23 79.3 43.7 6.4e-08 31.8 0.2 7.9 8 0 0 8 8 8 7 MORN repeat DUF1419 PF07215.6 ETO19146.1 - 0.13 12.1 1.0 2.7 7.9 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1419) Alpha_kinase PF02816.13 ETO19147.1 - 1.1e-35 122.9 0.1 2.3e-35 121.9 0.1 1.5 1 1 0 1 1 1 1 Alpha-kinase family Pkinase PF00069.20 ETO19148.1 - 0.041 13.0 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Eapp_C PF10238.4 ETO19150.1 - 0.49 10.2 25.9 0.19 11.5 9.2 3.1 2 0 0 2 2 2 0 E2F-associated phosphoprotein Ion_trans PF00520.26 ETO19151.1 - 7.9e-24 84.0 0.1 2.2e-22 79.2 0.1 2.1 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.7 ETO19151.1 - 0.57 8.5 4.4 4.3 5.6 1.3 2.2 1 1 1 2 2 2 0 Polycystin cation channel ATG27 PF09451.5 ETO19152.1 - 0.0016 17.7 2.6 0.033 13.4 1.7 2.1 1 1 0 1 1 1 1 Autophagy-related protein 27 DUF3816 PF12822.2 ETO19152.1 - 0.0017 18.2 0.5 0.0026 17.6 0.4 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3816) OAD_gamma PF04277.8 ETO19152.1 - 0.0032 17.8 1.4 1 9.7 0.0 2.3 2 0 0 2 2 2 1 Oxaloacetate decarboxylase, gamma chain BLVR PF06375.6 ETO19152.1 - 0.0043 16.8 3.3 0.0043 16.8 2.3 1.7 2 0 0 2 2 2 1 Bovine leukaemia virus receptor (BLVR) RIC3 PF15361.1 ETO19152.1 - 0.0069 16.6 5.9 1 9.5 0.0 2.1 2 0 0 2 2 2 1 Resistance to inhibitors of cholinesterase homologue 3 EphA2_TM PF14575.1 ETO19152.1 - 0.011 16.0 0.4 2.6 8.5 0.0 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF92 PF01940.11 ETO19152.1 - 0.029 13.5 0.0 2.3 7.3 0.0 2.0 2 0 0 2 2 2 0 Integral membrane protein DUF92 DUF2207 PF09972.4 ETO19152.1 - 0.038 12.5 1.2 0.056 12.0 0.8 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4366 PF14283.1 ETO19152.1 - 0.044 13.1 8.4 0.14 11.5 5.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) SpoIIIAH PF12685.2 ETO19152.1 - 0.05 13.0 3.5 0.055 12.9 0.0 2.0 1 1 1 2 2 2 0 SpoIIIAH-like protein FAM176 PF14851.1 ETO19152.1 - 0.055 13.1 0.0 0.055 13.1 0.0 2.2 1 1 1 2 2 2 0 FAM176 family Peptidase_M56 PF05569.6 ETO19152.1 - 0.08 11.9 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF202 PF02656.10 ETO19152.1 - 0.12 12.5 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF202) PH_10 PF15411.1 ETO19152.1 - 0.2 11.8 3.8 0.41 10.8 2.6 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Peptidase_S49_N PF08496.5 ETO19152.1 - 0.23 11.2 7.5 0.73 9.6 3.8 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal NfeD PF01957.13 ETO19152.1 - 0.42 10.7 4.5 1.7 8.7 0.4 2.7 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding CPSF73-100_C PF11718.3 ETO19152.1 - 0.99 8.7 3.9 1.4 8.2 2.7 1.3 1 1 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term DUF3377 PF11857.3 ETO19152.1 - 1.1 8.8 5.1 0.13 11.9 0.3 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3377) Vpu PF00558.14 ETO19152.1 - 2 7.9 0.0 2 7.9 0.0 2.6 2 1 0 2 2 1 0 Vpu protein DUF3899 PF13038.1 ETO19152.1 - 3.4 7.8 9.1 7 6.8 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3899) TMEM154 PF15102.1 ETO19152.1 - 6.3 6.5 10.8 0.86 9.3 0.2 2.2 1 1 1 2 2 2 0 TMEM154 protein family TSGP1 PF07771.6 ETO19152.1 - 9.8 6.0 10.3 23 4.8 7.1 1.6 1 1 0 1 1 1 0 Tick salivary peptide group 1 RNA_pol_Rpb1_5 PF04998.12 ETO19153.1 - 0.2 10.8 4.3 0.23 10.7 3.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Ubiquitin_3 PF14836.1 ETO19153.1 - 0.45 10.2 4.1 0.47 10.1 0.1 2.3 1 1 1 2 2 2 0 Ubiquitin-like domain HEAT PF02985.17 ETO19154.1 - 5.2e-17 60.3 4.2 0.00042 20.1 0.1 9.7 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.1 ETO19154.1 - 9.3e-16 57.8 2.2 0.0023 18.1 0.0 6.6 5 1 2 7 7 7 4 HEAT repeats HEAT_EZ PF13513.1 ETO19154.1 - 3.9e-13 49.4 2.7 0.15 12.5 0.4 8.5 7 2 2 9 9 8 3 HEAT-like repeat SF3b1 PF08920.5 ETO19154.1 - 4.9e-11 42.8 0.1 9.2e-11 41.9 0.1 1.5 1 0 0 1 1 1 1 Splicing factor 3B subunit 1 CLASP_N PF12348.3 ETO19154.1 - 2.2e-05 23.9 0.0 0.24 10.7 0.0 4.6 5 1 1 6 6 6 1 CLASP N terminal Arm PF00514.18 ETO19154.1 - 5.4e-05 22.8 0.5 1.9 8.4 0.0 6.0 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat NUC173 PF08161.7 ETO19154.1 - 0.00082 18.7 0.1 4.9 6.4 0.0 4.6 5 0 0 5 5 5 1 NUC173 domain TIP120 PF08623.5 ETO19154.1 - 0.0022 17.5 0.7 0.035 13.7 0.0 3.1 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) MMS19_C PF12460.3 ETO19154.1 - 0.0071 15.1 0.0 1.3 7.6 0.0 3.5 4 0 0 4 4 4 1 RNAPII transcription regulator C-terminal Adaptin_N PF01602.15 ETO19154.1 - 0.0092 14.3 3.9 1.2 7.3 0.0 3.9 3 2 1 5 5 5 2 Adaptin N terminal region MMS19_N PF14500.1 ETO19154.1 - 0.01 15.1 0.1 0.67 9.1 0.0 3.4 4 0 0 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II Proteasom_PSMB PF10508.4 ETO19154.1 - 0.064 11.5 1.2 34 2.5 0.0 3.7 2 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit RIX1 PF08167.7 ETO19154.1 - 0.27 10.9 3.2 12 5.5 0.0 4.2 4 1 0 4 4 4 0 rRNA processing/ribosome biogenesis DUF3802 PF12290.3 ETO19154.1 - 0.37 11.1 3.8 7.9 6.8 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3802) Myb_DNA-bind_6 PF13921.1 ETO19156.1 - 0.079 13.0 1.9 0.93 9.6 0.1 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF645 PF04875.7 ETO19157.1 - 0.044 13.4 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF645 RNase_HII PF01351.13 ETO19158.1 - 0.1 12.2 0.7 0.13 11.8 0.5 1.1 1 0 0 1 1 1 0 Ribonuclease HII ACT_7 PF13840.1 ETO19159.1 - 0.055 13.0 0.1 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 ACT domain DUF3979 PF13141.1 ETO19159.1 - 0.56 10.1 3.0 4.6 7.1 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3979) Pkinase PF00069.20 ETO19161.1 - 4.6e-60 202.9 0.3 4.6e-60 202.9 0.2 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO19161.1 - 2.9e-32 111.7 0.1 2.9e-32 111.7 0.1 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO19161.1 - 4.3e-06 25.8 0.0 9e-06 24.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Vma12 PF11712.3 ETO19161.1 - 0.11 12.1 5.6 0.42 10.3 3.9 2.0 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3682 PF12446.3 ETO19162.1 - 0.54 10.5 5.5 1.3 9.3 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) ACCA PF03255.9 ETO19162.1 - 2.3 7.7 7.6 0.18 11.3 0.4 2.1 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF3824 PF12868.2 ETO19162.1 - 7.9 7.4 9.3 0.14 13.0 1.4 1.8 2 1 0 2 2 2 0 Domain of unknwon function (DUF3824) MCPsignal PF00015.16 ETO19165.1 - 0.0051 16.3 20.3 0.13 11.8 3.0 2.4 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1241 PF06840.6 ETO19165.1 - 0.016 14.4 4.0 1.6 7.9 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1241) CK2S PF15011.1 ETO19165.1 - 0.48 10.2 3.7 1.9 8.2 0.6 2.2 1 1 1 2 2 2 0 Casein Kinase 2 substrate DASH_Duo1 PF08651.5 ETO19165.1 - 1.8 8.1 4.7 3.6 7.2 0.4 2.6 2 0 0 2 2 2 0 DASH complex subunit Duo1 DUF3708 PF12501.3 ETO19165.1 - 2.5 7.9 10.4 0.86 9.4 4.5 2.1 2 1 0 2 2 2 0 Phosphate ATP-binding cassette transporter DUF948 PF06103.6 ETO19165.1 - 8.2 6.3 20.4 2.5 8.0 2.6 3.9 3 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) ECH PF00378.15 ETO19166.1 - 1.1e-36 126.1 0.0 4.1e-23 81.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family Metallophos PF00149.23 ETO19166.1 - 0.085 12.2 0.0 3.5 6.9 0.0 2.3 1 1 1 2 2 2 0 Calcineurin-like phosphoesterase TPP_enzyme_C PF02775.16 ETO19166.1 - 0.11 12.0 0.0 2.3 7.7 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain GatB_Yqey PF02637.13 ETO19167.1 - 0.023 14.4 0.9 0.026 14.2 0.6 1.4 1 1 0 1 1 1 0 GatB domain DUF4064 PF13273.1 ETO19168.1 - 0.0061 16.6 0.5 0.0061 16.6 0.4 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF4064) FAM176 PF14851.1 ETO19168.1 - 0.011 15.3 0.8 0.011 15.3 0.6 3.5 1 1 2 3 3 3 0 FAM176 family PEHE PF15275.1 ETO19168.1 - 0.019 15.3 0.5 0.019 15.3 0.3 3.7 3 2 0 3 3 3 0 PEHE domain 7TM_GPCR_Srw PF10324.4 ETO19168.1 - 0.072 12.2 7.6 0.21 10.6 5.3 1.9 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw MFS_2 PF13347.1 ETO19168.1 - 0.078 11.3 3.3 0.3 9.4 0.0 2.0 2 0 0 2 2 2 0 MFS/sugar transport protein IncA PF04156.9 ETO19168.1 - 0.12 11.9 1.5 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 IncA protein DUF3357 PF11837.3 ETO19168.1 - 0.13 12.0 0.1 0.13 12.0 0.1 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) TMEM154 PF15102.1 ETO19168.1 - 0.32 10.7 13.8 0.042 13.5 5.6 2.4 1 1 1 2 2 2 0 TMEM154 protein family Podoplanin PF05808.6 ETO19168.1 - 2.5 7.6 8.1 0.073 12.6 0.6 2.0 2 0 0 2 2 2 0 Podoplanin DUF3377 PF11857.3 ETO19168.1 - 2.5 7.8 9.1 0.13 11.9 1.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3377) TPR_2 PF07719.12 ETO19169.1 - 0.0043 16.8 0.3 0.014 15.2 0.2 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO19169.1 - 0.0097 15.4 1.2 0.023 14.2 0.8 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO19169.1 - 0.013 15.2 1.0 0.048 13.4 0.7 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Sel1 PF08238.7 ETO19169.1 - 0.61 10.8 4.0 0.23 12.1 0.3 2.0 2 0 0 2 2 2 0 Sel1 repeat LRR_6 PF13516.1 ETO19170.1 - 0.0039 17.0 0.6 0.0039 17.0 0.4 3.8 3 0 0 3 3 3 1 Leucine Rich repeat DUF3924 PF13062.1 ETO19170.1 - 0.0051 16.6 0.1 0.023 14.5 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3924) AIPR PF10592.4 ETO19171.1 - 0.0013 18.0 5.8 0.002 17.5 4.0 1.2 1 0 0 1 1 1 1 AIPR protein zf-CCCH_2 PF14608.1 ETO19172.1 - 0.13 12.2 0.8 0.13 12.2 0.6 2.2 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type PRK PF00485.13 ETO19174.1 - 1.8e-33 115.7 2.9 1.7e-29 102.8 0.1 2.8 1 1 2 3 3 3 2 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 ETO19174.1 - 6.7e-06 26.9 0.0 1.3e-05 26.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETO19174.1 - 2.8e-05 24.4 1.3 3.9e-05 23.9 0.0 1.9 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 ETO19174.1 - 0.00063 19.4 0.5 0.0067 16.1 0.3 2.5 2 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B CoaE PF01121.15 ETO19174.1 - 0.0036 16.7 0.5 0.13 11.6 0.0 2.3 2 0 0 2 2 2 1 Dephospho-CoA kinase CPT PF07931.7 ETO19174.1 - 0.052 13.1 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.7 ETO19174.1 - 0.066 12.3 0.1 0.31 10.0 0.0 2.1 3 0 0 3 3 3 0 Zeta toxin Thymidylate_kin PF02223.12 ETO19174.1 - 0.078 12.3 0.1 9 5.6 0.1 2.2 2 0 0 2 2 2 0 Thymidylate kinase DUF1777 PF08648.7 ETO19175.1 - 1.3 8.7 68.5 0.74 9.5 19.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) SprA-related PF12118.3 ETO19175.1 - 2.5 7.3 42.7 0.43 9.8 7.7 2.1 2 0 0 2 2 2 0 SprA-related family Neur_chan_memb PF02932.11 ETO19176.1 - 0.58 10.0 6.4 0.81 9.5 4.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3807 PF12720.2 ETO19176.1 - 4.8 7.3 16.3 6.7 6.8 11.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Pkinase PF00069.20 ETO19177.1 - 2.4e-54 184.1 0.0 3.4e-54 183.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO19177.1 - 7.5e-23 80.9 0.0 1.2e-22 80.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO19177.1 - 4.7e-05 22.5 0.0 7.7e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETO19177.1 - 6.8e-05 21.9 0.0 0.00012 21.1 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 ETO19177.1 - 0.0022 17.7 0.5 0.007 16.1 0.1 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 ETO19177.1 - 0.075 11.8 0.3 0.3 9.8 0.0 2.0 2 1 0 2 2 2 0 Poxvirus serine/threonine protein kinase rRNA_processing PF08524.6 ETO19178.1 - 0.00012 21.8 18.4 0.00012 21.8 12.7 3.4 1 1 1 2 2 2 1 rRNA processing MRP-L28 PF09812.4 ETO19178.1 - 0.0027 17.5 8.8 0.0027 17.5 6.1 2.8 2 1 0 2 2 2 1 Mitochondrial ribosomal protein L28 Pkinase PF00069.20 ETO19179.1 - 2.4e-18 66.2 5.9 5.7e-15 55.1 4.1 3.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO19179.1 - 3e-08 33.0 0.5 0.00073 18.6 0.1 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase HSP70 PF00012.15 ETO19180.1 - 3.7e-166 553.5 0.4 1.4e-165 551.6 0.3 1.7 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 ETO19180.1 - 5.8e-06 25.1 0.1 4e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 ETO19180.1 - 0.0088 15.8 1.4 0.91 9.3 0.0 3.5 3 1 0 3 3 3 1 Cell division protein FtsA DDR PF08841.5 ETO19180.1 - 0.042 12.6 0.4 2.8 6.6 0.0 2.5 3 0 0 3 3 3 0 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 ETO19180.1 - 0.054 13.1 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Ras PF00071.17 ETO19181.1 - 7.4e-48 161.9 0.2 1.3e-47 161.1 0.1 1.4 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO19181.1 - 5.4e-20 72.0 0.3 2.5e-19 69.9 0.0 2.4 3 0 0 3 3 3 1 Miro-like protein Arf PF00025.16 ETO19181.1 - 3.1e-11 42.8 0.0 4.9e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.12 ETO19181.1 - 0.00077 19.0 0.6 0.007 15.9 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 ETO19181.1 - 0.006 16.0 0.0 0.025 14.0 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 ETO19181.1 - 0.021 14.0 0.0 0.044 12.9 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 ETO19181.1 - 0.056 13.4 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Phage_holin_1 PF04531.8 ETO19181.1 - 0.42 10.6 2.3 1.1 9.3 0.1 2.6 2 0 0 2 2 2 0 Bacteriophage holin Reo_sigmaC PF04582.7 ETO19182.1 - 0.31 10.1 11.4 0.077 12.1 4.4 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Dpy19 PF10034.4 ETO19184.1 - 0.025 12.7 0.4 0.025 12.7 0.3 1.6 2 0 0 2 2 2 0 Q-cell neuroblast polarisation Nucleoside_tran PF01733.13 ETO19185.1 - 0.081 12.0 0.2 0.081 12.0 0.1 1.9 1 1 1 2 2 2 0 Nucleoside transporter DUF1183 PF06682.7 ETO19185.1 - 0.12 11.9 0.1 0.12 11.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) DUF2208 PF09973.4 ETO19185.1 - 0.28 10.3 5.1 0.27 10.4 2.8 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2208) ERM PF00769.14 ETO19185.1 - 0.7 9.3 43.0 0.12 11.9 12.1 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Spc7 PF08317.6 ETO19185.1 - 1 7.9 29.4 1.7 7.2 9.0 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein FliD_N PF02465.13 ETO19185.1 - 1.5 9.1 10.9 2.8 8.3 0.5 2.7 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus TMPIT PF07851.8 ETO19185.1 - 3 6.8 17.1 0.68 8.9 1.3 2.3 2 0 0 2 2 2 0 TMPIT-like protein Fez1 PF06818.10 ETO19185.1 - 4.9 7.1 29.8 1.2 9.1 10.0 2.4 2 0 0 2 2 2 0 Fez1 DUF87 PF01935.12 ETO19185.1 - 5.1 6.8 18.9 0.26 11.0 4.7 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF1024 PF06260.7 ETO19185.1 - 5.1 7.3 11.7 0.43 10.7 2.8 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF1024) DUF3810 PF12725.2 ETO19185.1 - 6.6 5.5 7.3 1.5 7.6 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) Serinc PF03348.10 ETO19185.1 - 7.5 5.1 7.0 0.41 9.2 0.6 1.8 1 1 1 2 2 2 0 Serine incorporator (Serinc) APG6 PF04111.7 ETO19185.1 - 8.4 5.3 35.8 7.7 5.4 9.6 2.5 2 0 0 2 2 2 0 Autophagy protein Apg6 Tetraspannin PF00335.15 ETO19186.1 - 0.00068 18.9 0.0 0.0043 16.3 0.0 2.0 1 1 1 2 2 2 1 Tetraspanin family Rax2 PF12768.2 ETO19186.1 - 0.013 14.7 0.1 0.026 13.7 0.1 1.6 1 0 0 1 1 1 0 Cortical protein marker for cell polarity EphA2_TM PF14575.1 ETO19186.1 - 0.03 14.7 0.2 0.097 13.0 0.1 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MFS_2 PF13347.1 ETO19186.1 - 0.038 12.3 0.7 0.056 11.8 0.5 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein MFS_1 PF07690.11 ETO19186.1 - 0.047 12.4 0.3 0.073 11.7 0.2 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily Syndecan PF01034.15 ETO19186.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain Shisa PF13908.1 ETO19186.1 - 1.1 9.3 4.3 17 5.5 2.9 2.7 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator YrvL PF14184.1 ETO19187.1 - 4.1 7.2 12.8 8.2 6.2 8.9 1.6 1 1 0 1 1 1 0 Regulatory protein YrvL DUF4582 PF15189.1 ETO19188.1 - 0.073 12.2 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4582) DUF4342 PF14242.1 ETO19188.1 - 0.31 10.8 2.5 0.53 10.0 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) WD40 PF00400.27 ETO19189.1 - 2.1e-45 151.0 20.4 1e-13 50.5 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO19189.1 - 4.4e-06 25.2 0.9 0.002 16.5 0.0 2.3 1 1 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.3 ETO19189.1 - 1.3e-05 23.5 8.8 0.084 10.9 0.0 4.6 2 2 1 4 4 4 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO19189.1 - 0.00018 21.0 0.1 0.00045 19.7 0.0 1.6 1 1 0 1 1 1 1 PQQ-like domain Mid2 PF04478.7 ETO19189.1 - 0.00035 20.0 1.6 0.03 13.7 0.0 3.1 2 1 1 3 3 3 1 Mid2 like cell wall stress sensor PD40 PF07676.7 ETO19189.1 - 0.0016 18.0 2.8 0.49 10.1 0.0 5.0 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 ETO19189.1 - 0.0018 17.4 1.4 0.4 9.7 0.0 3.8 2 2 3 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Str_synth PF03088.11 ETO19189.1 - 0.003 17.5 0.0 0.068 13.2 0.0 3.1 4 0 0 4 4 4 1 Strictosidine synthase Nucleoporin_N PF08801.6 ETO19189.1 - 0.011 14.4 8.3 5.6 5.5 0.0 3.8 1 1 1 3 3 3 0 Nup133 N terminal like Kinesin PF00225.18 ETO19190.1 - 2.6e-114 381.4 1.0 2.6e-114 381.4 0.7 2.7 2 1 0 2 2 2 1 Kinesin motor domain Mac PF12464.3 ETO19190.1 - 0.09 12.8 6.4 0.028 14.4 1.3 2.7 3 0 0 3 3 3 0 Maltose acetyltransferase DUF4605 PF15378.1 ETO19191.1 - 0.01 15.4 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4605) Ctr PF04145.10 ETO19191.1 - 0.016 15.2 0.1 0.027 14.5 0.1 1.3 1 0 0 1 1 1 0 Ctr copper transporter family SHR3_chaperone PF08229.6 ETO19191.1 - 0.091 11.7 0.2 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 Secretin_N_2 PF07655.8 ETO19191.1 - 0.13 12.7 12.7 0.27 11.6 8.8 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain TM2 PF05154.11 ETO19191.1 - 0.15 12.3 1.8 0.27 11.4 1.2 1.4 1 0 0 1 1 1 0 TM2 domain Pkinase PF00069.20 ETO19192.1 - 3.9e-25 88.4 1.8 1.3e-20 73.6 0.6 3.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO19192.1 - 6e-09 35.3 0.0 7.6e-06 25.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Spore_coat_CotO PF14153.1 ETO19192.1 - 0.00015 21.3 10.3 0.00017 21.1 7.1 1.1 1 0 0 1 1 1 1 Spore coat protein CotO Ycf1 PF05758.7 ETO19192.1 - 0.004 14.9 6.6 0.004 14.9 4.5 1.1 1 0 0 1 1 1 1 Ycf1 SAPS PF04499.10 ETO19192.1 - 0.017 13.7 3.9 0.017 13.7 2.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pox_ser-thr_kin PF05445.6 ETO19192.1 - 0.042 12.6 0.0 0.067 11.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase BUD22 PF09073.5 ETO19192.1 - 0.15 11.0 20.1 0.18 10.8 14.0 1.1 1 0 0 1 1 1 0 BUD22 DUF2201_N PF13203.1 ETO19192.1 - 0.16 11.1 4.2 0.2 10.7 2.9 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF1510 PF07423.6 ETO19192.1 - 0.17 11.2 22.1 0.22 10.8 15.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NARP1 PF12569.3 ETO19192.1 - 0.17 10.5 9.2 0.19 10.4 6.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Vfa1 PF08432.5 ETO19192.1 - 0.22 11.5 15.5 0.34 10.9 10.8 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Pox_Ag35 PF03286.9 ETO19192.1 - 0.31 10.5 16.5 0.46 9.9 11.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PTRF_SDPR PF15237.1 ETO19192.1 - 0.34 10.2 13.4 0.45 9.8 9.3 1.2 1 0 0 1 1 1 0 PTRF/SDPR family CDC45 PF02724.9 ETO19192.1 - 0.35 8.8 15.7 0.42 8.5 10.9 1.1 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.8 ETO19192.1 - 0.44 9.0 8.5 0.59 8.6 5.9 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Nop14 PF04147.7 ETO19192.1 - 0.46 8.3 23.2 0.56 8.0 16.1 1.1 1 0 0 1 1 1 0 Nop14-like family DUF913 PF06025.7 ETO19192.1 - 0.55 8.9 4.9 0.69 8.5 3.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Daxx PF03344.10 ETO19192.1 - 0.61 8.5 23.0 0.75 8.2 15.9 1.1 1 0 0 1 1 1 0 Daxx Family Pilt PF15453.1 ETO19192.1 - 0.69 9.5 10.7 0.86 9.2 7.4 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Merozoite_SPAM PF07133.6 ETO19192.1 - 0.7 9.7 30.5 0.92 9.3 21.2 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Raftlin PF15250.1 ETO19192.1 - 0.7 8.3 8.2 0.9 7.9 5.7 1.1 1 0 0 1 1 1 0 Raftlin Hid1 PF12722.2 ETO19192.1 - 0.77 7.3 7.5 0.86 7.2 5.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DDHD PF02862.12 ETO19192.1 - 0.82 9.4 8.6 1.1 9.0 6.0 1.2 1 0 0 1 1 1 0 DDHD domain DUF1764 PF08576.5 ETO19192.1 - 0.99 10.2 13.1 1.6 9.5 9.1 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Tim54 PF11711.3 ETO19192.1 - 1.1 7.7 9.6 1.3 7.5 6.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Serinc PF03348.10 ETO19192.1 - 1.4 7.5 4.3 1.8 7.2 3.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2151 PF10221.4 ETO19192.1 - 1.5 6.9 11.8 1.7 6.7 8.2 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator RNA_pol_3_Rpc31 PF11705.3 ETO19192.1 - 1.5 8.6 19.6 2.1 8.2 13.6 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DHHW PF14286.1 ETO19192.1 - 1.8 7.8 10.3 2.3 7.4 7.1 1.1 1 0 0 1 1 1 0 DHHW protein Paf1 PF03985.8 ETO19192.1 - 2.7 6.6 21.8 3.3 6.3 15.1 1.1 1 0 0 1 1 1 0 Paf1 RR_TM4-6 PF06459.7 ETO19192.1 - 2.7 7.8 18.9 3.6 7.4 13.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 V_ATPase_I PF01496.14 ETO19192.1 - 2.7 5.7 5.9 3 5.5 4.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IPK PF03770.11 ETO19192.1 - 2.8 7.5 10.5 11 5.6 7.3 2.0 1 1 0 1 1 1 0 Inositol polyphosphate kinase RP-C_C PF11800.3 ETO19192.1 - 2.9 7.5 9.1 4.2 7.0 6.3 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region Trypan_PARP PF05887.6 ETO19192.1 - 2.9 7.7 21.4 4.1 7.2 14.8 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MIP-T3 PF10243.4 ETO19192.1 - 3.3 6.0 24.2 4.2 5.7 16.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RRN3 PF05327.6 ETO19192.1 - 3.8 5.5 11.1 5.6 4.9 7.7 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2146 PF10220.4 ETO19192.1 - 4 5.3 10.5 5 4.9 7.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Zip PF02535.17 ETO19192.1 - 4.6 6.1 9.4 6.1 5.7 6.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter TRAP_alpha PF03896.11 ETO19192.1 - 4.6 6.1 15.8 7.3 5.4 11.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sec62 PF03839.11 ETO19192.1 - 5.4 6.3 10.9 7.4 5.9 7.6 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 PTPLA PF04387.9 ETO19193.1 - 3.2e-24 85.2 10.3 4.3e-24 84.7 7.1 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA FtsX PF02687.16 ETO19193.1 - 1.7 8.4 5.7 7.6 6.3 4.0 2.0 1 1 0 1 1 1 0 FtsX-like permease family Patatin PF01734.17 ETO19195.1 - 0.03 14.2 0.3 0.032 14.1 0.2 1.1 1 0 0 1 1 1 0 Patatin-like phospholipase Aldedh PF00171.17 ETO19196.1 - 3.6e-29 101.4 0.0 4.2e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Trypan_PARP PF05887.6 ETO19197.1 - 0.0069 16.2 26.4 0.0069 16.2 18.3 1.6 1 1 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Muted PF14942.1 ETO19197.1 - 1.9 8.3 10.3 5.1 6.9 0.3 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein CDC27 PF09507.5 ETO19197.1 - 3.9 6.5 7.4 5.4 6.1 5.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TT_ORF1 PF02956.9 ETO19197.1 - 4.4 5.6 5.6 5.9 5.2 3.9 1.1 1 0 0 1 1 1 0 TT viral orf 1 Neisseria_TspB PF05616.8 ETO19197.1 - 8.1 4.6 7.6 11 4.2 5.3 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein CENP-B_dimeris PF09026.5 ETO19199.1 - 0.0021 18.2 11.7 0.0027 17.8 8.1 1.3 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Ead_Ea22 PF13935.1 ETO19199.1 - 0.012 15.9 1.3 0.035 14.4 0.9 1.6 1 1 0 1 1 1 0 Ead/Ea22-like protein SDA1 PF05285.7 ETO19199.1 - 0.13 11.5 17.5 0.16 11.2 12.1 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 ETO19199.1 - 0.59 8.1 9.4 0.59 8.1 6.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 ETO19199.1 - 3 7.4 15.2 5.6 6.5 10.5 1.5 1 1 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.7 ETO19199.1 - 3.6 5.4 16.8 3.6 5.3 11.7 1.1 1 0 0 1 1 1 0 Nop14-like family DUF3053 PF11254.3 ETO19200.1 - 0.0048 16.1 0.1 0.0068 15.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3053) Fer4_20 PF14691.1 ETO19200.1 - 0.023 14.2 0.5 0.043 13.4 0.3 1.4 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster YgaB PF14182.1 ETO19200.1 - 0.12 12.6 4.9 0.072 13.3 1.7 1.9 2 0 0 2 2 2 0 YgaB-like protein WD40 PF00400.27 ETO19201.1 - 3.7e-42 140.7 5.4 1.6e-10 40.4 0.1 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat Ricin_B_lectin PF00652.17 ETO19201.1 - 0.0048 16.9 0.2 0.012 15.5 0.1 1.5 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Nucleoporin_N PF08801.6 ETO19201.1 - 0.019 13.7 1.5 0.84 8.3 0.0 2.7 1 1 2 3 3 3 0 Nup133 N terminal like PD40 PF07676.7 ETO19201.1 - 0.28 10.9 1.8 8.4 6.1 0.0 2.9 3 1 1 4 4 4 0 WD40-like Beta Propeller Repeat Clusterin PF01093.12 ETO19203.1 - 0.034 12.9 0.2 0.034 12.9 0.1 1.1 1 0 0 1 1 1 0 Clusterin GMC_oxred_C PF05199.8 ETO19204.1 - 0.017 15.3 0.3 0.12 12.7 0.1 2.1 2 0 0 2 2 2 0 GMC oxidoreductase DER1 PF04511.10 ETO19205.1 - 5e-33 114.2 4.4 6.2e-33 113.9 3.1 1.1 1 0 0 1 1 1 1 Der1-like family OST3_OST6 PF04756.8 ETO19205.1 - 0.062 12.8 2.5 0.06 12.9 0.4 1.8 1 1 0 1 1 1 0 OST3 / OST6 family FA_desaturase PF00487.19 ETO19205.1 - 7.7 5.8 13.7 1.4e+02 1.7 9.5 2.5 1 1 0 1 1 1 0 Fatty acid desaturase zf-DNA_Pol PF08996.5 ETO19206.1 - 9.1e-32 109.9 5.7 1.1e-31 109.6 4.0 1.1 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger zinc_ribbon_5 PF13719.1 ETO19206.1 - 0.0062 16.0 0.1 0.018 14.6 0.1 1.8 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_4 PF13717.1 ETO19206.1 - 0.015 14.9 0.2 0.05 13.3 0.2 1.9 1 0 0 1 1 1 0 zinc-ribbon domain IBR PF01485.16 ETO19206.1 - 0.13 12.1 7.0 1.6 8.6 0.1 3.5 2 1 0 2 2 2 0 IBR domain Rib_5-P_isom_A PF06026.9 ETO19207.1 - 0.097 11.9 0.3 1.5 8.1 0.0 2.2 1 1 1 2 2 2 0 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DUF3377 PF11857.3 ETO19207.1 - 0.19 11.3 4.9 2.3 7.8 0.5 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3377) WhiA_N PF10298.4 ETO19208.1 - 0.13 12.0 3.5 0.95 9.3 0.4 2.3 2 0 0 2 2 2 0 WhiA N-terminal LAGLIDADG-like domain Polyoma_agno PF01736.11 ETO19208.1 - 0.52 9.9 2.6 8.8 6.0 0.4 2.5 2 0 0 2 2 2 0 Polyomavirus agnoprotein RVT_connect PF06815.8 ETO19209.1 - 0.12 12.2 2.1 0.1 12.4 0.5 1.5 2 0 0 2 2 2 0 Reverse transcriptase connection domain DcpS_C PF11969.3 ETO19210.1 - 0.017 15.3 0.9 0.017 15.3 0.6 2.1 1 1 1 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding ATP-synt_ab PF00006.20 ETO19210.1 - 0.071 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Thiolase_N PF00108.18 ETO19211.1 - 1e-25 90.2 0.0 1.2e-25 90.0 0.0 1.0 1 0 0 1 1 1 1 Thiolase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 ETO19212.1 - 2.9e-06 27.4 0.1 0.00044 20.3 0.0 2.2 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 ETO19212.1 - 0.015 14.8 0.0 0.035 13.6 0.0 1.6 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, middle domain WD40 PF00400.27 ETO19214.1 - 1.7e-05 24.4 0.1 0.0019 18.0 0.0 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat PD40 PF07676.7 ETO19214.1 - 0.00079 19.0 0.5 0.018 14.7 0.2 2.4 1 1 1 2 2 2 1 WD40-like Beta Propeller Repeat Peptidase_S9_N PF02897.10 ETO19214.1 - 0.065 11.8 0.0 0.13 10.8 0.0 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain zf-RING_5 PF14634.1 ETO19215.1 - 0.061 13.0 0.4 0.061 13.0 0.3 1.9 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.20 ETO19215.1 - 0.13 11.9 2.5 0.44 10.2 0.3 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO19215.1 - 0.16 11.8 4.0 0.23 11.3 0.6 2.4 2 0 0 2 2 2 0 Ring finger domain Pox_Ag35 PF03286.9 ETO19215.1 - 0.16 11.4 10.3 0.064 12.7 3.3 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein zf-DHHC PF01529.15 ETO19216.1 - 7.4e-20 71.0 7.1 1e-19 70.6 4.9 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase TCR_zetazeta PF11628.3 ETO19216.1 - 0.078 12.4 5.1 0.15 11.5 3.5 1.4 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 zeta chain XAP5 PF04921.9 ETO19217.1 - 8.5e-69 231.7 5.1 8.5e-69 231.7 3.5 2.9 1 1 2 3 3 3 1 XAP5, circadian clock regulator DRIM PF07539.7 ETO19217.1 - 0.4 10.0 3.8 0.17 11.2 0.8 1.6 2 0 0 2 2 2 0 Down-regulated in metastasis Histone PF00125.19 ETO19218.1 - 1.7e-23 82.5 0.7 8.4e-23 80.2 0.2 2.1 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 ETO19218.1 - 0.05 13.7 0.1 0.09 12.9 0.1 1.3 1 0 0 1 1 1 0 Kinetochore component CENP-S 5TM-5TMR_LYT PF07694.7 ETO19218.1 - 0.13 11.5 1.8 0.2 10.9 1.2 1.2 1 0 0 1 1 1 0 5TMR of 5TMR-LYT Aminotran_5 PF00266.14 ETO19219.1 - 3.8e-26 91.6 0.0 9.4e-16 57.5 0.0 3.1 2 1 0 2 2 2 2 Aminotransferase class-V DB PF01682.14 ETO19219.1 - 0.033 14.2 0.3 0.08 12.9 0.2 1.6 1 0 0 1 1 1 0 DB module CDC45 PF02724.9 ETO19220.1 - 0.096 10.7 6.6 0.098 10.6 4.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 ETO19220.1 - 2.4 7.4 10.9 3.1 7.1 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pox_Ag35 PF03286.9 ETO19220.1 - 3.2 7.2 8.2 5 6.6 5.7 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CobT PF06213.7 ETO19220.1 - 3.7 6.5 14.0 4.9 6.1 9.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Peptidase_M56 PF05569.6 ETO19221.1 - 0.0034 16.3 0.1 0.008 15.1 0.1 1.5 1 0 0 1 1 1 1 BlaR1 peptidase M56 Renin_r PF07850.9 ETO19221.1 - 0.12 12.7 3.6 0.13 12.6 0.8 2.3 2 0 0 2 2 2 0 Renin receptor-like protein Mucin PF01456.12 ETO19221.1 - 4.8 6.9 23.1 0.19 11.5 10.2 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein ABC_tran PF00005.22 ETO19222.1 - 1.2e-06 28.9 0.5 1.2e-06 28.9 0.4 2.4 2 1 0 2 2 2 1 ABC transporter AAA_25 PF13481.1 ETO19222.1 - 0.0073 15.7 0.1 0.016 14.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 ETO19222.1 - 0.011 14.8 0.2 0.019 14.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 ETO19222.1 - 0.017 15.9 0.2 0.017 15.9 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.1 ETO19222.1 - 0.021 14.7 3.8 0.033 14.1 0.5 2.5 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 ETO19222.1 - 0.042 14.1 0.2 0.042 14.1 0.1 2.4 2 1 0 2 2 2 0 AAA domain NACHT PF05729.7 ETO19222.1 - 0.09 12.4 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 ETO19222.1 - 0.21 11.5 0.6 0.38 10.6 0.5 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.1 ETO19222.1 - 0.44 10.4 9.5 0.28 11.1 0.2 2.2 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 ETO19222.1 - 1.3 8.7 9.5 0.61 9.8 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 ABC2_membrane PF01061.19 ETO19224.1 - 1.5e-14 53.6 20.8 1.5e-14 53.6 14.4 2.0 2 1 0 2 2 2 1 ABC-2 type transporter DEP PF00610.16 ETO19225.1 - 1e-07 31.6 0.2 3e-07 30.0 0.1 1.8 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CDC45 PF02724.9 ETO19225.1 - 3.9 5.3 11.5 6.1 4.7 8.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_85 PF03644.8 ETO19226.1 - 6.2e-49 166.8 9.1 1.7e-48 165.3 6.3 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 85 Glyco_hydro_18 PF00704.23 ETO19226.1 - 0.038 13.4 0.0 0.071 12.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 UCH PF00443.24 ETO19227.1 - 1.5e-12 47.1 0.7 3.2e-12 46.1 0.5 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 ETO19228.1 - 1.5e-63 208.5 15.5 2e-12 46.4 0.0 7.4 7 0 0 7 7 6 6 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO19228.1 - 7.8e-07 29.0 11.4 0.088 13.0 0.1 6.8 7 0 0 7 7 7 3 Kelch motif Nup160 PF11715.3 ETO19228.1 - 6.6e-06 24.5 5.9 0.041 12.0 0.1 5.0 1 1 5 6 6 6 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO19228.1 - 1.3e-05 24.8 0.2 0.00034 20.1 0.1 2.7 1 1 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO19228.1 - 3.1e-05 22.4 1.1 0.015 13.6 0.1 3.3 1 1 3 4 4 4 4 Cytochrome D1 heme domain Kelch_2 PF07646.10 ETO19228.1 - 0.00098 18.7 2.3 15 5.5 0.0 4.9 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.1 ETO19228.1 - 0.001 18.7 2.2 0.17 11.6 0.1 4.1 3 1 1 4 4 3 1 Galactose oxidase, central domain Nbas_N PF15492.1 ETO19228.1 - 0.0044 16.1 0.3 2.8 6.9 0.0 3.7 1 1 3 4 4 4 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 ETO19228.1 - 0.035 13.7 9.3 77 3.1 0.1 6.1 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat GF_recep_IV PF14843.1 ETO19228.1 - 0.041 13.4 2.0 1.6 8.3 0.2 2.8 2 0 0 2 2 2 0 Growth factor receptor domain IV Kelch_5 PF13854.1 ETO19228.1 - 0.36 10.8 4.9 5.1 7.1 0.3 3.7 4 0 0 4 4 4 0 Kelch motif Proteasome_A_N PF10584.4 ETO19228.1 - 1.2 8.5 14.9 8.4 5.8 0.0 5.7 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 ETO19229.1 - 9.5e-60 196.4 32.4 6.2e-11 41.7 0.0 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO19229.1 - 1.7e-15 56.1 4.3 1.6e-06 26.5 0.1 5.2 3 3 2 5 5 5 5 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO19229.1 - 0.046 13.6 0.0 0.13 12.1 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3601) HAD PF12710.2 ETO19229.1 - 0.38 10.8 4.6 10 6.2 0.0 3.7 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase WD40 PF00400.27 ETO19230.1 - 2.7e-22 77.7 12.2 8.1e-11 41.3 0.1 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO19230.1 - 0.0023 16.1 0.7 0.074 11.1 0.2 2.7 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO19230.1 - 0.0051 15.6 1.6 0.59 8.8 0.1 2.7 1 1 2 3 3 3 2 Nup133 N terminal like WD40 PF00400.27 ETO19231.1 - 1.2e-55 183.5 23.5 7.4e-11 41.4 0.4 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO19231.1 - 9.7e-09 33.8 6.1 0.038 12.1 0.1 5.0 1 1 2 4 4 4 4 Nucleoporin Nup120/160 WD40 PF00400.27 ETO19232.1 - 2.3e-57 188.9 25.2 3.7e-11 42.4 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO19232.1 - 2e-09 36.1 11.0 0.0012 17.0 0.2 5.8 2 1 4 6 6 6 6 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO19232.1 - 0.029 14.1 1.5 11 5.8 0.1 4.0 2 2 2 4 4 4 0 Ciliary BBSome complex subunit 2, middle region BetaGal_dom3 PF13363.1 ETO19232.1 - 0.13 11.6 0.1 1.7 8.0 0.0 2.7 3 0 0 3 3 3 0 Beta-galactosidase, domain 3 WD40 PF00400.27 ETO19233.1 - 5.1e-65 213.2 26.7 2e-12 46.4 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO19233.1 - 5.9e-06 24.7 7.9 0.027 12.6 0.3 4.5 1 1 3 5 5 5 3 Nucleoporin Nup120/160 SWIRM PF04433.12 ETO19235.1 - 0.15 12.2 4.4 0.38 10.8 3.1 1.9 1 1 0 1 1 1 0 SWIRM domain KIP1 PF07765.7 ETO19235.1 - 0.37 10.6 3.2 0.33 10.8 1.1 1.9 2 0 0 2 2 2 0 KIP1-like protein HSP70 PF00012.15 ETO19235.1 - 1 7.1 8.2 1.4 6.7 5.7 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF4137 PF13593.1 ETO19237.1 - 1.2e-17 63.9 11.5 1.5e-17 63.7 7.9 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) CoA_binding_3 PF13727.1 ETO19237.1 - 0.97 9.2 3.9 3.7 7.3 2.7 1.9 1 1 0 1 1 1 0 CoA-binding domain Pkinase PF00069.20 ETO19238.1 - 1.3e-28 99.8 0.2 4.4e-14 52.2 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO19238.1 - 1e-16 60.8 0.1 5.8e-07 28.8 0.0 3.1 2 1 1 3 3 3 3 Protein tyrosine kinase CDC45 PF02724.9 ETO19238.1 - 0.00012 20.3 16.1 0.00014 20.0 11.2 1.3 1 0 0 1 1 1 1 CDC45-like protein TFIIA PF03153.8 ETO19238.1 - 0.00029 20.8 14.4 0.00029 20.8 10.0 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CENP-T PF15511.1 ETO19238.1 - 0.00078 18.7 9.4 0.00093 18.5 6.5 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Daxx PF03344.10 ETO19238.1 - 0.0018 16.9 25.1 0.0024 16.4 17.4 1.1 1 0 0 1 1 1 1 Daxx Family Nop14 PF04147.7 ETO19238.1 - 0.002 16.1 28.2 0.0026 15.7 19.5 1.1 1 0 0 1 1 1 1 Nop14-like family DUF1510 PF07423.6 ETO19238.1 - 0.011 15.0 19.8 0.018 14.3 13.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2457 PF10446.4 ETO19238.1 - 0.02 13.6 41.5 0.028 13.1 28.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FYDLN_acid PF09538.5 ETO19238.1 - 0.17 12.4 31.3 0.38 11.3 21.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) SAPS PF04499.10 ETO19238.1 - 1.1 7.8 10.1 1.3 7.5 7.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PPP4R2 PF09184.6 ETO19238.1 - 1.1 8.7 24.5 1.8 8.0 17.0 1.4 1 0 0 1 1 1 0 PPP4R2 Dicty_REP PF05086.7 ETO19238.1 - 2.7 5.6 12.4 4.6 4.8 8.6 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Nop25 PF09805.4 ETO19238.1 - 3.6 7.6 26.5 0.47 10.5 15.6 1.5 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) BUD22 PF09073.5 ETO19238.1 - 4.1 6.3 30.4 0.83 8.6 18.9 1.3 2 0 0 2 2 2 0 BUD22 NPR3 PF03666.8 ETO19238.1 - 7.5 4.9 10.2 10 4.4 7.1 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RRN3 PF05327.6 ETO19238.1 - 8.4 4.3 20.2 11 3.9 14.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ras PF00071.17 ETO19239.1 - 2.1e-08 33.7 2.0 2.5e-08 33.4 1.4 1.2 1 0 0 1 1 1 1 Ras family Ribosomal_L30_N PF08079.7 ETO19239.1 - 0.00065 19.6 0.6 0.00065 19.6 0.4 2.6 2 1 0 2 2 2 1 Ribosomal L30 N-terminal domain MRP-L51 PF10244.4 ETO19239.1 - 0.29 11.1 6.1 1.2 9.1 4.2 1.8 1 1 0 1 1 1 0 Mitochondrial ribosomal subunit LMBR1 PF04791.11 ETO19241.1 - 0.084 11.4 2.9 0.11 11.0 2.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Raftlin PF15250.1 ETO19241.1 - 0.09 11.2 7.8 0.11 11.0 5.4 1.1 1 0 0 1 1 1 0 Raftlin Neur_chan_memb PF02932.11 ETO19241.1 - 0.092 12.6 3.0 0.13 12.1 2.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Paramyxo_ncap PF00973.14 ETO19241.1 - 0.1 11.2 2.1 0.13 10.9 1.5 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Menin PF05053.8 ETO19241.1 - 0.56 8.2 10.9 0.66 8.0 7.5 1.1 1 0 0 1 1 1 0 Menin CobT PF06213.7 ETO19241.1 - 2.4 7.2 12.4 3.1 6.8 8.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2207 PF09972.4 ETO19242.1 - 0.00034 19.3 5.0 0.00042 19.0 3.5 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF912 PF06024.7 ETO19242.1 - 0.0036 17.3 1.6 0.0049 16.8 0.4 1.7 1 1 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2956 PF11169.3 ETO19242.1 - 0.0043 16.9 1.4 0.0089 15.9 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2956) DUF4448 PF14610.1 ETO19242.1 - 0.02 14.3 0.1 0.03 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Peroxin-13_N PF04088.8 ETO19242.1 - 0.042 13.7 3.1 0.082 12.8 2.1 1.4 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DUF2540 PF10802.3 ETO19242.1 - 0.046 13.3 0.1 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2540) 7tm_1 PF00001.16 ETO19242.1 - 0.079 12.0 6.2 0.097 11.7 4.0 1.3 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF3753 PF12575.3 ETO19242.1 - 0.11 12.2 0.2 0.11 12.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) m04gp34like PF12216.3 ETO19242.1 - 0.27 10.5 4.1 0.66 9.2 0.1 2.3 1 1 1 2 2 2 0 Immune evasion protein Vma12 PF11712.3 ETO19242.1 - 0.41 10.3 3.5 0.59 9.8 2.2 1.4 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase zf-AN1 PF01428.11 ETO19243.1 - 7e-07 29.0 0.5 1.4e-06 28.0 0.3 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger G-patch PF01585.18 ETO19244.1 - 6e-08 32.3 0.5 1.2e-07 31.3 0.3 1.5 1 0 0 1 1 1 1 G-patch domain DUF4187 PF13821.1 ETO19244.1 - 0.002 17.6 1.5 0.67 9.5 1.0 2.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch_2 PF12656.2 ETO19244.1 - 0.013 15.3 0.5 0.04 13.7 0.0 2.1 2 0 0 2 2 2 0 DExH-box splicing factor binding site TPR_12 PF13424.1 ETO19245.1 - 3e-25 87.9 0.0 3.3e-13 49.3 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO19245.1 - 3.5e-14 52.1 0.5 1.2e-09 37.6 0.1 2.4 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 ETO19245.1 - 3.5e-10 39.0 1.9 5.2e-05 22.6 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO19245.1 - 2.2e-09 36.5 1.1 0.007 16.2 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO19245.1 - 8.6e-09 34.5 2.1 0.002 17.7 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO19245.1 - 1.2e-08 34.5 0.0 0.00062 19.6 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO19245.1 - 8.4e-06 25.2 0.1 0.21 11.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO19245.1 - 0.012 16.2 0.0 15 6.5 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 ETO19245.1 - 0.039 14.0 0.0 0.17 12.0 0.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 ATP-synt_F PF01990.12 ETO19245.1 - 0.24 11.8 3.5 0.1 12.9 0.5 1.9 2 0 0 2 2 2 0 ATP synthase (F/14-kDa) subunit BLVR PF06375.6 ETO19247.1 - 0.0047 16.7 15.2 0.0058 16.4 10.5 1.2 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) Pox_Ag35 PF03286.9 ETO19247.1 - 0.12 11.8 18.1 0.14 11.6 12.6 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Drc1-Sld2 PF11719.3 ETO19247.1 - 0.31 10.0 13.1 0.34 9.9 9.1 1.0 1 0 0 1 1 1 0 DNA replication and checkpoint protein Glycoprotein_G PF00802.14 ETO19247.1 - 0.31 10.1 5.3 0.34 10.0 3.7 1.2 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G SLY PF12485.3 ETO19247.1 - 0.5 10.6 9.1 0.56 10.4 6.3 1.2 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein CDC27 PF09507.5 ETO19247.1 - 2.6 7.1 18.8 3 6.9 13.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Eapp_C PF10238.4 ETO19247.1 - 3 7.7 10.7 5 7.0 7.4 1.6 1 1 0 1 1 1 0 E2F-associated phosphoprotein DUF1168 PF06658.7 ETO19247.1 - 5.6 6.4 20.7 8.7 5.8 14.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1168) TFIIE-A_C-term PF11521.3 ETO19247.1 - 6.7 6.7 10.7 0.67 9.9 3.2 2.1 1 1 1 2 2 2 0 C-terminal general transcription factor TFIIE alpha MRI PF15325.1 ETO19247.1 - 7.2 7.6 12.1 11 7.1 8.3 1.3 1 1 0 1 1 1 0 Modulator of retrovirus infection SR-25 PF10500.4 ETO19247.1 - 7.3 5.9 16.0 8.8 5.7 11.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Daxx PF03344.10 ETO19247.1 - 8.2 4.7 14.8 9.6 4.5 10.2 1.0 1 0 0 1 1 1 0 Daxx Family DUF2151 PF10221.4 ETO19247.1 - 8.3 4.4 10.3 8.7 4.3 7.1 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Ion_trans PF00520.26 ETO19248.1 - 5.1e-32 110.7 8.0 7.9e-32 110.1 5.6 1.2 1 0 0 1 1 1 1 Ion transport protein Na_trans_assoc PF06512.8 ETO19248.1 - 0.0013 18.8 0.1 0.0021 18.1 0.0 1.3 1 0 0 1 1 1 1 Sodium ion transport-associated PKD_channel PF08016.7 ETO19248.1 - 0.017 13.5 10.6 0.034 12.5 0.3 3.0 2 1 1 3 3 3 0 Polycystin cation channel DUF2973 PF11189.3 ETO19248.1 - 0.029 14.1 1.1 1.1 9.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2973) ABC2_membrane_2 PF12679.2 ETO19248.1 - 0.11 11.3 3.3 6.1 5.6 0.0 2.5 2 0 0 2 2 2 0 ABC-2 family transporter protein Lig_chan PF00060.21 ETO19248.1 - 0.39 10.4 2.0 0.39 10.4 0.0 2.0 2 0 0 2 2 2 0 Ligand-gated ion channel Lectin_C PF00059.16 ETO19249.1 - 8.4e-18 64.9 7.7 1.8e-17 63.8 2.4 4.6 4 1 0 4 4 4 2 Lectin C-type domain Fibrinogen_C PF00147.13 ETO19249.1 - 1.7e-05 24.5 0.1 4.4e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain PAN_2 PF08276.6 ETO19249.1 - 0.5 10.2 7.1 1.8 8.4 1.5 2.6 2 0 0 2 2 2 0 PAN-like domain tRNA-synt_1d PF00750.14 ETO19250.1 - 6.4e-24 84.4 0.5 5.3e-19 68.2 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (R) Rad4 PF03835.10 ETO19250.1 - 0.019 14.4 2.5 0.025 13.9 1.7 1.2 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain Rpn3_C PF08375.6 ETO19250.1 - 0.022 15.1 1.7 0.16 12.3 2.0 1.9 2 0 0 2 2 2 0 Proteasome regulatory subunit C-terminal Chisel PF15355.1 ETO19250.1 - 0.42 10.6 2.3 0.74 9.8 1.6 1.3 1 0 0 1 1 1 0 Stretch-responsive small skeletal muscle X protein, Chisel YmaF PF12788.2 ETO19252.1 - 0.0062 16.6 0.8 0.0062 16.6 0.5 2.2 3 0 0 3 3 3 1 YmaF family P3A PF08727.6 ETO19252.1 - 0.064 12.6 0.2 0.17 11.2 0.0 1.7 2 0 0 2 2 2 0 Poliovirus 3A protein like Ras PF00071.17 ETO19253.1 - 1.8e-56 189.9 0.3 2.2e-56 189.7 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO19253.1 - 1.6e-19 70.5 0.1 3.4e-19 69.5 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO19253.1 - 4.9e-14 51.9 0.0 6.3e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETO19253.1 - 1.5e-07 30.7 0.2 9.1e-07 28.2 0.1 1.9 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 ETO19253.1 - 0.0028 17.1 0.0 0.0052 16.2 0.0 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Phage_integrase PF00589.17 ETO19253.1 - 0.046 13.3 0.2 0.063 12.9 0.1 1.1 1 0 0 1 1 1 0 Phage integrase family MMR_HSR1 PF01926.18 ETO19253.1 - 0.047 13.6 0.0 0.1 12.5 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase PTEN_C2 PF10409.4 ETO19254.1 - 0.0025 17.5 0.1 0.0076 15.9 0.1 1.9 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein EXS PF03124.9 ETO19255.1 - 3.8e-27 95.2 2.3 4.5e-27 94.9 1.6 1.0 1 0 0 1 1 1 1 EXS family Pkinase PF00069.20 ETO19256.1 - 3e-43 147.8 0.0 3.8e-43 147.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO19256.1 - 3.7e-17 62.2 0.0 4.7e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO19256.1 - 4e-06 25.9 0.0 5.3e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETO19256.1 - 4.1e-06 25.9 0.3 6.2e-06 25.4 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 ETO19256.1 - 0.0042 16.4 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Mucin PF01456.12 ETO19258.1 - 0.074 12.8 27.1 0.15 11.8 18.8 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein FctA PF12892.2 ETO19258.1 - 4 8.3 14.1 0.82 10.5 1.5 2.5 2 0 0 2 2 2 0 T surface-antigen of pili DUF3627 PF12299.3 ETO19260.1 - 0.0057 16.6 0.7 0.012 15.5 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3627) Glyco_hydro_47 PF01532.15 ETO19262.1 - 2.6e-28 98.9 0.1 3.2e-28 98.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 HEAT PF02985.17 ETO19263.1 - 1.8e-09 36.8 6.4 0.0017 18.2 0.2 4.6 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 ETO19263.1 - 1.7e-06 28.1 0.4 0.0008 19.6 0.1 2.5 2 0 0 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 ETO19263.1 - 6.4e-06 26.5 3.6 0.53 10.8 0.0 4.3 4 1 1 5 5 5 2 HEAT-like repeat CLASP_N PF12348.3 ETO19263.1 - 2.1e-05 23.9 0.4 0.12 11.6 0.0 2.3 2 0 0 2 2 2 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 ETO19263.1 - 0.00015 22.0 0.5 0.036 14.4 0.2 2.7 2 2 0 2 2 2 1 Vacuolar 14 Fab1-binding region MOR2-PAG1_N PF14222.1 ETO19263.1 - 0.064 11.9 0.4 2.3 6.7 0.0 2.1 2 0 0 2 2 2 0 Cell morphogenesis N-terminal Cnd1 PF12717.2 ETO19263.1 - 0.11 12.3 0.3 2.4 7.9 0.1 2.5 2 2 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.5 ETO19263.1 - 0.11 12.0 0.1 1.4 8.4 0.0 2.3 2 1 0 2 2 2 0 TATA-binding protein interacting (TIP20) Adaptin_N PF01602.15 ETO19263.1 - 0.12 10.6 0.3 1.2 7.3 0.1 2.0 2 0 0 2 2 2 0 Adaptin N terminal region Wbp11 PF09429.5 ETO19264.1 - 0.0065 16.4 6.5 0.01 15.8 4.5 1.3 1 0 0 1 1 1 1 WW domain binding protein 11 TFIIF_alpha PF05793.7 ETO19264.1 - 0.14 10.4 9.5 0.15 10.3 6.6 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SSP160 PF06933.6 ETO19264.1 - 1 7.2 19.5 1.1 7.1 13.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Draxin PF15550.1 ETO19264.1 - 1.4 8.5 9.1 1.5 8.3 6.3 1.0 1 0 0 1 1 1 0 Draxin DUF3824 PF12868.2 ETO19264.1 - 1.7 9.5 5.2 1.8 9.4 3.5 1.3 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) Rtf2 PF04641.7 ETO19264.1 - 2.4 7.3 11.9 3 6.9 8.2 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Peptidase_S64 PF08192.6 ETO19264.1 - 4.5 5.4 9.8 4.6 5.4 6.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 NST1 PF13945.1 ETO19264.1 - 7.6 6.5 13.0 8.7 6.3 8.5 1.5 1 1 0 1 1 1 0 Salt tolerance down-regulator Asp PF00026.18 ETO19265.1 - 2.8e-07 30.1 0.0 3.8e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 ETO19265.1 - 0.0002 20.9 0.0 0.052 13.0 0.0 2.3 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal F5_F8_type_C PF00754.20 ETO19266.1 - 0.00032 20.5 2.0 0.023 14.5 0.0 2.9 3 0 0 3 3 3 2 F5/8 type C domain Sad1_UNC PF07738.8 ETO19266.1 - 0.0091 15.7 9.2 2.8 7.7 1.0 4.0 4 0 0 4 4 4 2 Sad1 / UNC-like C-terminal CAP_N PF01213.14 ETO19266.1 - 0.13 11.5 2.2 0.2 10.9 1.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Plasmodium_Vir PF05795.6 ETO19267.1 - 0.04 13.1 11.0 0.19 10.8 1.8 2.0 1 1 1 2 2 2 0 Plasmodium vivax Vir protein T2SF PF00482.18 ETO19267.1 - 0.068 13.0 2.9 0.15 11.9 2.0 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Neur_chan_memb PF02932.11 ETO19267.1 - 0.073 12.9 4.3 0.11 12.3 3.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4544 PF15077.1 ETO19267.1 - 0.2 11.1 5.5 0.29 10.5 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) CD34_antigen PF06365.7 ETO19267.1 - 0.3 10.7 5.9 4 7.0 4.2 2.4 2 1 0 2 2 2 0 CD34/Podocalyxin family Rifin_STEVOR PF02009.11 ETO19267.1 - 0.35 10.4 22.1 0.7 9.4 15.3 1.5 1 1 0 1 1 1 0 Rifin/stevor family ABC2_membrane_3 PF12698.2 ETO19267.1 - 0.69 8.8 11.2 0.74 8.7 5.2 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein TMEM154 PF15102.1 ETO19267.1 - 3.4 7.3 16.9 7.9 6.1 10.1 2.5 2 1 0 2 2 2 0 TMEM154 protein family DUF4448 PF14610.1 ETO19267.1 - 5.4 6.4 8.9 2.6 7.4 2.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF4448) DUF912 PF06024.7 ETO19267.1 - 5.8 7.0 22.4 1.7e+02 2.3 0.0 3.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pkinase PF00069.20 ETO19268.1 - 5.1e-18 65.1 4.3 8.3e-18 64.4 3.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO19268.1 - 2.9e-14 52.7 1.3 8.5e-14 51.2 0.9 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 ETO19268.1 - 0.0077 15.5 0.3 0.022 14.1 0.0 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 ETO19268.1 - 0.019 14.6 0.2 0.029 14.1 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sushi_2 PF09014.5 ETO19268.1 - 0.07 12.9 0.7 0.18 11.6 0.5 1.7 1 1 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain DUF2930 PF11152.3 ETO19268.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2930) UPF0449 PF15136.1 ETO19269.1 - 1.8 8.8 13.4 0.76 10.0 2.2 3.0 2 1 1 3 3 3 0 Uncharacterised protein family UPF0449 GLTSCR1 PF15249.1 ETO19269.1 - 2.5 8.2 8.0 5.4 7.1 2.7 2.6 2 1 0 2 2 2 0 Glioma tumor suppressor candidate region Med9 PF07544.8 ETO19269.1 - 8 6.2 18.3 0.54 10.0 2.0 3.1 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 PQQ_3 PF13570.1 ETO19270.1 - 3.2e-05 24.0 0.1 0.28 11.4 0.0 3.4 3 0 0 3 3 3 2 PQQ-like domain WD40 PF00400.27 ETO19270.1 - 0.00054 19.7 0.0 0.015 15.2 0.0 3.4 4 0 0 4 4 4 1 WD domain, G-beta repeat PQQ_2 PF13360.1 ETO19270.1 - 0.0038 16.7 0.0 0.2 11.0 0.0 3.2 3 1 1 4 4 4 1 PQQ-like domain AvrE PF11725.3 ETO19270.1 - 0.014 12.4 17.1 0.62 7.0 12.5 2.1 2 0 0 2 2 2 0 Pathogenicity factor Corona_nucleoca PF00937.13 ETO19270.1 - 2.9 6.7 25.6 6 5.7 17.7 1.4 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein BUD22 PF09073.5 ETO19270.1 - 6.2 5.7 46.1 0.066 12.2 23.7 2.3 2 0 0 2 2 2 0 BUD22 CDC27 PF09507.5 ETO19270.1 - 8.2 5.5 44.4 16 4.5 30.8 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MIP-T3 PF10243.4 ETO19271.1 - 0.00026 19.6 36.1 0.0004 19.0 25.0 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Ycf1 PF05758.7 ETO19271.1 - 0.00066 17.5 8.6 0.00082 17.2 6.0 1.2 1 0 0 1 1 1 1 Ycf1 RR_TM4-6 PF06459.7 ETO19271.1 - 0.029 14.2 16.7 0.064 13.1 11.6 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NADH_dehy_S2_C PF06444.6 ETO19271.1 - 0.05 13.9 0.1 0.14 12.5 0.1 1.7 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 C-terminus Hid1 PF12722.2 ETO19271.1 - 0.11 10.1 11.3 0.16 9.6 7.8 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Daxx PF03344.10 ETO19271.1 - 0.16 10.4 21.7 0.2 10.1 15.0 1.1 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 ETO19271.1 - 1.4 8.2 26.4 3.2 7.0 18.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Trypan_PARP PF05887.6 ETO19271.1 - 2.5 7.9 13.8 0.55 10.0 7.1 1.7 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) WBP-1 PF11669.3 ETO19272.1 - 0.0016 18.5 0.4 0.0042 17.1 0.1 1.8 2 0 0 2 2 2 1 WW domain-binding protein 1 NCA2 PF08637.5 ETO19272.1 - 0.084 11.7 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 ATP synthase regulation protein NCA2 RPEL PF02755.10 ETO19273.1 - 2e-08 33.3 33.0 0.08 12.3 0.6 10.8 13 0 0 13 13 13 6 RPEL repeat RRM_5 PF13893.1 ETO19274.1 - 0.091 12.6 0.0 0.29 11.0 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Exo_endo_phos PF03372.18 ETO19275.1 - 2e-14 54.1 0.0 2.9e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Nefa_Nip30_N PF10187.4 ETO19275.1 - 0.026 14.6 5.9 3.9 7.7 0.0 2.6 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 GBP_repeat PF02526.9 ETO19275.1 - 0.041 13.2 0.0 0.11 11.8 0.0 1.7 1 0 0 1 1 1 0 Glycophorin-binding protein Abhydrolase_5 PF12695.2 ETO19276.1 - 7.3e-06 25.8 0.0 1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETO19276.1 - 0.0099 15.1 0.0 2.1 7.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.8 ETO19276.1 - 0.015 14.7 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.15 ETO19276.1 - 0.12 11.9 0.2 0.24 10.9 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold RRM_6 PF14259.1 ETO19277.1 - 1.8e-19 69.4 0.0 2e-06 27.7 0.0 6.0 6 0 0 6 6 6 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO19277.1 - 1.4e-14 53.4 0.0 0.0017 17.9 0.0 6.0 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO19277.1 - 2.1e-05 24.2 0.0 2.9 7.8 0.0 4.1 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KOW PF00467.24 ETO19278.1 - 0.023 14.4 0.1 0.69 9.7 0.0 2.3 2 0 0 2 2 2 0 KOW motif MIB_HERC2 PF06701.8 ETO19278.1 - 0.056 13.4 0.2 3.7 7.5 0.1 2.4 2 0 0 2 2 2 0 Mib_herc2 PPR_3 PF13812.1 ETO19279.1 - 0.0003 20.8 0.0 0.053 13.8 0.0 2.6 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 ETO19279.1 - 0.0011 18.9 0.0 0.029 14.3 0.0 2.6 2 0 0 2 2 2 1 PPR repeat family PPR PF01535.15 ETO19279.1 - 0.0076 16.1 0.1 0.024 14.5 0.0 2.0 1 0 0 1 1 1 1 PPR repeat PPR_1 PF12854.2 ETO19279.1 - 0.11 12.0 0.0 0.37 10.3 0.0 1.9 2 0 0 2 2 2 0 PPR repeat Glyco_transf_34 PF05637.7 ETO19283.1 - 5.4e-23 81.7 5.4 5.4e-23 81.7 3.7 1.9 2 1 0 2 2 2 1 galactosyl transferase GMA12/MNN10 family NST1 PF13945.1 ETO19284.1 - 2.5 8.1 10.3 3.5 7.6 7.1 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator NPR3 PF03666.8 ETO19284.1 - 2.9 6.3 7.5 3.2 6.1 5.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3566 PF12089.3 ETO19285.1 - 0.014 15.4 0.2 0.021 14.8 0.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of unknown function (DUF3566) DUF3433 PF11915.3 ETO19285.1 - 0.017 15.3 0.2 0.028 14.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3433) Hid1 PF12722.2 ETO19285.1 - 0.87 7.1 12.6 1.1 6.9 8.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MIP-T3 PF10243.4 ETO19285.1 - 8 4.7 27.7 9.8 4.5 19.2 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 EF-hand_7 PF13499.1 ETO19286.1 - 0.014 15.4 0.9 0.043 13.9 0.6 1.8 1 0 0 1 1 1 0 EF-hand domain pair Baculo_p24 PF05073.7 ETO19286.1 - 0.093 12.2 1.9 2 7.9 0.0 2.6 1 1 1 2 2 2 0 Baculovirus P24 capsid protein DUF551 PF04448.7 ETO19288.1 - 0.0043 17.7 1.6 0.024 15.3 1.1 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF551) DnaJ PF00226.26 ETO19290.1 - 2.8e-18 65.4 0.7 4.9e-18 64.6 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain FDF PF09532.5 ETO19290.1 - 1.7 9.1 13.0 3 8.4 9.0 1.4 1 0 0 1 1 1 0 FDF domain TrbI PF03743.9 ETO19290.1 - 2.8 7.3 7.1 4.7 6.6 0.1 2.1 2 0 0 2 2 2 0 Bacterial conjugation TrbI-like protein HELP PF03451.9 ETO19292.1 - 4e-05 23.0 0.0 0.00028 20.3 0.0 2.2 2 0 0 2 2 2 1 HELP motif WD40 PF00400.27 ETO19292.1 - 0.0005 19.8 0.6 0.18 11.7 0.0 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat WD40 PF00400.27 ETO19293.1 - 0.0085 15.9 10.4 8.1 6.5 0.2 5.6 5 1 0 5 5 5 2 WD domain, G-beta repeat Pox_P35 PF03213.9 ETO19293.1 - 0.056 12.4 0.3 0.089 11.7 0.2 1.3 1 0 0 1 1 1 0 Poxvirus P35 protein IKI3 PF04762.7 ETO19293.1 - 0.14 9.9 0.0 0.2 9.4 0.0 1.2 1 0 0 1 1 1 0 IKI3 family Afi1 PF07792.7 ETO19294.1 - 1.4e-07 31.5 0.7 6.1e-06 26.3 0.5 2.1 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SprA-related PF12118.3 ETO19294.1 - 0.085 12.1 5.9 0.11 11.7 4.1 1.1 1 0 0 1 1 1 0 SprA-related family Glypican PF01153.14 ETO19294.1 - 0.091 11.3 0.9 0.11 11.1 0.6 1.1 1 0 0 1 1 1 0 Glypican Vfa1 PF08432.5 ETO19294.1 - 0.12 12.3 7.5 0.17 11.8 5.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SURF2 PF05477.6 ETO19294.1 - 0.14 11.2 6.5 0.21 10.6 4.5 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) HSP90 PF00183.13 ETO19294.1 - 2.9 6.1 11.9 3.9 5.7 8.2 1.1 1 0 0 1 1 1 0 Hsp90 protein CDC45 PF02724.9 ETO19294.1 - 4.8 5.0 7.7 6.2 4.7 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Spore_YhcN_YlaJ PF09580.5 ETO19295.1 - 0.059 13.4 14.7 0.088 12.9 10.2 1.3 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Menin PF05053.8 ETO19295.1 - 0.29 9.2 9.3 0.45 8.6 6.4 1.4 1 0 0 1 1 1 0 Menin POX PF07526.6 ETO19295.1 - 2.4 8.3 4.3 1.5 9.0 1.9 1.6 2 0 0 2 2 2 0 Associated with HOX Macoilin PF09726.4 ETO19295.1 - 4.7 5.3 12.3 5.4 5.1 8.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Zip PF02535.17 ETO19295.1 - 5.5 5.8 5.2 6.8 5.5 3.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter IF3_C PF00707.17 ETO19297.1 - 0.063 13.0 6.5 0.27 10.9 0.6 3.9 3 1 1 4 4 4 0 Translation initiation factor IF-3, C-terminal domain DUF485 PF04341.7 ETO19297.1 - 0.067 12.9 0.4 0.6 9.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Atg14 PF10186.4 ETO19297.1 - 0.16 10.8 23.0 2 7.2 0.1 2.9 2 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 L71 PF02448.10 ETO19297.1 - 0.32 10.8 5.2 0.45 10.3 0.1 3.1 3 0 0 3 3 3 0 L71 family DUF3278 PF11683.3 ETO19297.1 - 0.87 9.5 4.8 0.48 10.4 0.1 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3278) APG6 PF04111.7 ETO19297.1 - 0.94 8.4 37.6 0.012 14.6 3.9 3.0 2 1 1 3 3 3 0 Autophagy protein Apg6 IncA PF04156.9 ETO19297.1 - 2.5 7.6 35.3 1.3 8.6 9.2 3.6 2 1 2 4 4 4 0 IncA protein DUF869 PF05911.6 ETO19297.1 - 2.9 5.9 30.2 4.6 5.3 20.7 1.5 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) Nup54 PF13874.1 ETO19297.1 - 5.5 6.6 25.8 7.8 6.1 7.6 4.0 2 2 1 3 3 3 0 Nucleoporin complex subunit 54 Tachylectin PF14517.1 ETO19299.1 - 0.037 13.3 0.9 1 8.6 0.0 2.4 2 0 0 2 2 2 0 Tachylectin Hyd_WA PF06462.7 ETO19299.1 - 0.048 13.3 0.0 6.4 6.5 0.0 3.3 3 0 0 3 3 3 0 Propeller DUF3609 PF12259.3 ETO19299.1 - 0.063 11.9 0.5 0.11 11.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) Ubiquitin_2 PF14560.1 ETO19301.1 - 4.7e-08 33.1 0.1 1.2e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 ETO19301.1 - 0.022 14.1 0.0 0.25 10.7 0.0 2.3 1 1 0 1 1 1 0 Ubiquitin family Apq12 PF12716.2 ETO19301.1 - 2 8.1 9.8 3.3 7.4 6.8 1.3 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis Metallophos PF00149.23 ETO19302.1 - 5.7e-10 38.9 3.3 9e-10 38.2 2.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 ETO19302.1 - 5.9e-10 39.1 0.3 8.7e-10 38.6 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Marek_A PF02124.10 ETO19304.1 - 0.18 11.2 4.1 0.1 12.0 0.4 2.0 2 0 0 2 2 2 0 Marek's disease glycoprotein A Tmemb_9 PF05434.6 ETO19304.1 - 0.63 9.7 6.0 1.3 8.7 4.2 1.5 1 0 0 1 1 1 0 TMEM9 TMEM154 PF15102.1 ETO19304.1 - 1.4 8.6 7.2 0.12 12.1 0.5 2.2 2 0 0 2 2 2 0 TMEM154 protein family Shisa PF13908.1 ETO19304.1 - 7.3 6.7 9.8 36 4.4 6.8 2.2 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator UDPG_MGDP_dh_N PF03721.9 ETO19306.1 - 2.2e-49 167.3 0.1 2.5e-49 167.1 0.1 1.0 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.10 ETO19306.1 - 1.1e-07 31.7 0.1 8.7e-07 28.9 0.1 1.9 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 ETO19306.1 - 8.6e-06 25.5 0.2 1.3e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 ETO19306.1 - 0.0014 18.1 0.2 0.0038 16.6 0.1 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 ETO19306.1 - 0.0033 17.1 0.1 0.0051 16.5 0.1 1.3 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 ETO19306.1 - 0.0035 16.5 0.1 0.0052 15.9 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 ETO19306.1 - 0.0088 16.0 0.4 0.012 15.5 0.2 1.4 1 1 0 1 1 1 1 TrkA-N domain Pyr_redox PF00070.22 ETO19306.1 - 0.023 15.1 0.5 0.043 14.2 0.4 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 ETO19306.1 - 0.075 12.5 0.3 0.13 11.7 0.2 1.6 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UPF0146 PF03686.8 ETO19306.1 - 0.086 12.6 0.3 0.14 12.0 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) SBP_bac_11 PF13531.1 ETO19306.1 - 0.095 12.3 0.1 0.23 11.0 0.0 1.6 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein DAO PF01266.19 ETO19306.1 - 0.15 10.9 0.9 0.29 10.0 0.6 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase K_channel_TID PF07941.6 ETO19307.1 - 0.67 10.2 14.4 0.11 12.6 2.1 2.9 2 1 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain S-antigen PF05756.6 ETO19308.1 - 0.0016 18.3 6.6 0.0016 18.3 4.6 2.2 2 0 0 2 2 2 1 S-antigen protein DUF2457 PF10446.4 ETO19308.1 - 0.0048 15.6 22.8 0.0062 15.3 15.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Daxx PF03344.10 ETO19308.1 - 0.96 7.8 12.9 1.1 7.6 8.9 1.1 1 0 0 1 1 1 0 Daxx Family Nop25 PF09805.4 ETO19308.1 - 1.9 8.5 12.0 3.5 7.7 8.3 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) RXT2_N PF08595.6 ETO19308.1 - 3.8 7.3 15.8 8.6 6.1 0.0 2.2 1 1 1 2 2 2 0 RXT2-like, N-terminal RCC1 PF00415.13 ETO19311.1 - 3.2e-28 97.6 16.2 8.8e-08 32.2 0.1 7.9 6 2 1 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO19311.1 - 1e-21 75.9 5.5 1e-08 34.5 1.6 5.8 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat TMEM125 PF15109.1 ETO19312.1 - 0.047 13.8 0.1 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 TMEM125 protein family RGS PF00615.14 ETO19312.1 - 0.049 13.7 3.5 0.38 10.8 0.8 3.0 2 1 0 2 2 2 0 Regulator of G protein signaling domain Aminotran_5 PF00266.14 ETO19314.1 - 0.0006 18.6 0.1 1 8.0 0.0 2.5 2 1 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 ETO19314.1 - 0.001 17.4 0.0 0.0017 16.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.14 ETO19314.1 - 0.0093 14.4 0.0 0.22 9.9 0.0 2.2 2 1 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain DUF4148 PF13663.1 ETO19315.1 - 0.12 12.2 0.0 0.36 10.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) RAB3GAP2_N PF14655.1 ETO19316.1 - 6e-20 71.6 0.1 1.9e-09 37.0 0.0 2.4 2 0 0 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus Nucleotid_trans PF03407.11 ETO19317.1 - 1.3e-19 70.8 0.6 1.8e-19 70.3 0.4 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Aminotran_1_2 PF00155.16 ETO19319.1 - 1.7e-24 86.4 0.0 1.9e-24 86.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 ETO19319.1 - 0.017 14.2 0.0 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 ETO19319.1 - 0.11 10.7 0.0 0.11 10.7 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Ank_2 PF12796.2 ETO19320.1 - 8.9e-27 93.2 5.3 6.8e-16 58.3 0.1 3.9 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO19320.1 - 1.1e-22 79.9 3.6 2.3e-06 27.9 0.0 6.2 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 ETO19320.1 - 1.1e-22 78.6 5.3 4.4e-05 23.0 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 ETO19320.1 - 9e-20 68.7 3.1 0.0039 17.2 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 ETO19320.1 - 8.8e-17 60.7 4.6 7.6e-05 22.8 0.1 5.5 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.12 ETO19321.1 - 1.3e-38 132.5 0.0 2.3e-29 102.2 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 ETO19321.1 - 1.7e-24 86.4 2.3 1.1e-17 64.1 0.0 2.5 2 1 1 3 3 3 2 Protein kinase domain Ashwin PF15323.1 ETO19321.1 - 0.13 12.2 11.6 0.21 11.5 8.1 1.2 1 0 0 1 1 1 0 Developmental protein Apc15p PF05841.6 ETO19321.1 - 0.14 12.9 10.6 0.26 12.0 7.4 1.4 1 0 0 1 1 1 0 Apc15p protein Secretin_N_2 PF07655.8 ETO19321.1 - 0.49 10.8 17.3 1 9.8 12.0 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain Menin PF05053.8 ETO19321.1 - 0.64 8.1 8.1 0.86 7.6 5.6 1.1 1 0 0 1 1 1 0 Menin Rad4 PF03835.10 ETO19322.1 - 0.13 11.6 0.0 0.13 11.6 0.0 2.8 4 0 0 4 4 4 0 Rad4 transglutaminase-like domain UCH PF00443.24 ETO19323.1 - 2.7e-09 36.5 2.4 3e-08 33.0 1.6 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Frag1 PF10277.4 ETO19323.1 - 0.016 14.6 0.2 0.026 14.0 0.2 1.3 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family DUF4366 PF14283.1 ETO19323.1 - 0.55 9.6 3.8 36 3.6 1.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) Fzo_mitofusin PF04799.8 ETO19326.1 - 0.022 14.1 0.2 0.029 13.7 0.2 1.3 1 0 0 1 1 1 0 fzo-like conserved region SlyX PF04102.7 ETO19326.1 - 0.043 14.1 0.4 0.071 13.4 0.3 1.4 1 0 0 1 1 1 0 SlyX DASH_Hsk3 PF08227.6 ETO19326.1 - 0.078 13.1 3.5 0.14 12.3 2.4 1.4 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like DUF1151 PF06625.6 ETO19326.1 - 0.079 12.6 0.6 0.079 12.6 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) NapB PF03892.9 ETO19326.1 - 0.11 12.1 2.7 0.15 11.7 1.8 1.3 1 0 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) Sugarporin_N PF11471.3 ETO19326.1 - 0.12 12.0 0.5 0.12 12.0 0.4 1.8 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension DASH_Spc19 PF08287.6 ETO19326.1 - 0.14 11.7 4.3 0.17 11.4 3.0 1.3 1 1 0 1 1 1 0 Spc19 Spc24 PF08286.6 ETO19326.1 - 0.51 10.0 3.2 0.19 11.4 0.5 1.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 KLRAQ PF10205.4 ETO19326.1 - 0.89 9.6 4.7 0.25 11.3 0.3 1.9 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein BLVR PF06375.6 ETO19326.1 - 1 9.1 6.6 1.5 8.6 4.6 1.3 1 1 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) TBPIP PF07106.8 ETO19326.1 - 1.1 8.7 7.0 0.18 11.3 0.5 1.9 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DASH_Spc34 PF08657.5 ETO19326.1 - 1.7 8.2 6.8 0.32 10.6 1.5 1.8 1 1 1 2 2 2 0 DASH complex subunit Spc34 DUF3847 PF12958.2 ETO19326.1 - 3.1 7.6 8.3 0.13 11.9 1.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) CR6_interact PF10147.4 ETO19326.1 - 7.8 5.7 8.9 20 4.3 6.2 1.6 1 1 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 SAM_2 PF07647.12 ETO19327.1 - 0.0086 15.9 0.1 4.6 7.1 0.0 2.7 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) DUF244 PF03112.9 ETO19327.1 - 0.014 14.9 2.9 0.014 14.9 2.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein family (ORF7) DUF Abhydrolase_6 PF12697.2 ETO19328.1 - 2.5e-13 50.4 0.0 4.1e-13 49.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETO19328.1 - 2.2e-11 43.6 0.0 1.9e-10 40.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETO19328.1 - 2.8e-09 36.8 0.0 4.7e-09 36.1 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 ETO19328.1 - 7.5e-08 32.1 0.6 1.3e-07 31.3 0.4 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 ETO19328.1 - 0.00011 21.6 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 ETO19328.1 - 0.00026 20.2 0.0 0.00051 19.3 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Thioesterase PF00975.15 ETO19328.1 - 0.00039 20.7 0.1 0.0019 18.4 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain Lipase_3 PF01764.20 ETO19328.1 - 0.004 16.7 0.0 0.0089 15.6 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 ETO19328.1 - 0.022 14.3 0.0 0.065 12.8 0.0 1.8 2 1 1 3 3 3 0 PGAP1-like protein Ubie_methyltran PF01209.13 ETO19328.1 - 0.12 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family UCH PF00443.24 ETO19331.1 - 4.7e-07 29.1 0.6 8.4e-07 28.3 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Helicase_C PF00271.26 ETO19332.1 - 0.00067 19.4 0.5 0.0015 18.3 0.4 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain FixQ PF05545.6 ETO19332.1 - 0.018 14.6 4.6 0.11 12.1 0.0 2.4 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF418 PF04235.7 ETO19332.1 - 0.031 13.9 0.5 0.34 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF418) Claudin_3 PF06653.6 ETO19332.1 - 0.14 11.8 8.1 0.15 11.7 4.9 1.6 2 0 0 2 2 2 0 Tight junction protein, Claudin-like Corona_nucleoca PF00937.13 ETO19333.1 - 0.44 9.4 10.6 0.47 9.3 7.4 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF2072 PF09845.4 ETO19333.1 - 1.1 9.1 4.0 0.58 10.0 1.5 1.5 1 1 1 2 2 2 0 Zn-ribbon containing protein (DUF2072) F-box-like_2 PF13013.1 ETO19334.1 - 0.016 14.9 1.1 0.028 14.1 0.7 1.5 1 1 0 1 1 1 0 F-box-like domain zf-C2H2_2 PF12756.2 ETO19335.1 - 0.0028 17.7 2.3 0.0028 17.7 1.6 2.1 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.5 ETO19335.1 - 0.017 15.0 0.3 0.047 13.6 0.2 1.8 1 0 0 1 1 1 0 Zinc ribbon domain 2OG-FeII_Oxy PF03171.15 ETO19336.1 - 3.1e-15 56.2 0.0 4.8e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily YqcI_YcgG PF08892.6 ETO19336.1 - 0.0017 17.9 0.1 0.0024 17.4 0.1 1.2 1 0 0 1 1 1 1 YqcI/YcgG family LmjF365940-deam PF14421.1 ETO19337.1 - 2.3e-19 69.5 0.2 3.9e-19 68.7 0.1 1.3 1 0 0 1 1 1 1 A distinct subfamily of CDD/CDA-like deaminases BBS1 PF14779.1 ETO19337.1 - 0.0043 16.0 1.5 0.0053 15.7 1.1 1.1 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 1 Vezatin PF12632.2 ETO19337.1 - 0.0045 16.0 0.7 0.0068 15.5 0.5 1.4 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes DUF2547 PF10818.3 ETO19337.1 - 0.072 13.7 2.4 0.3 11.7 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2547) PMT_C PF11647.3 ETO19337.1 - 0.1 12.2 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 YqzL PF14006.1 ETO19337.1 - 0.13 12.4 0.3 0.43 10.8 0.2 1.8 1 0 0 1 1 1 0 YqzL-like protein Neur_chan_memb PF02932.11 ETO19337.1 - 0.93 9.3 5.5 0.23 11.2 1.1 1.7 1 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region AAA_12 PF13087.1 ETO19337.1 - 1.9 7.7 8.2 0.15 11.4 1.0 1.9 1 1 1 2 2 2 0 AAA domain Trs65 PF12735.2 ETO19337.1 - 3.4 6.9 10.7 1.7 7.9 2.6 2.0 2 0 0 2 2 2 0 TRAPP trafficking subunit Trs65 GMC_oxred_N PF00732.14 ETO19338.1 - 3.4e-19 69.1 0.0 4.1e-10 39.3 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase DUF2967 PF11179.3 ETO19339.1 - 0.0084 15.6 4.7 0.18 11.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2967) GRIN_C PF15235.1 ETO19342.1 - 0.26 11.3 2.3 0.62 10.1 1.6 1.8 1 1 0 1 1 1 0 G protein-regulated inducer of neurite outgrowth C-terminus MMPL PF03176.10 ETO19344.1 - 8.6e-15 54.2 0.8 2e-08 33.3 0.1 2.1 2 0 0 2 2 2 2 MMPL family G-alpha PF00503.15 ETO19345.1 - 6.9e-10 38.1 0.5 9.4e-10 37.7 0.3 1.2 1 0 0 1 1 1 1 G-protein alpha subunit AAA_17 PF13207.1 ETO19345.1 - 0.0066 17.2 0.0 0.011 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF1389 PF07146.6 ETO19345.1 - 0.027 13.5 0.3 0.027 13.5 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1389) SRPRB PF09439.5 ETO19345.1 - 0.045 12.9 0.3 0.12 11.6 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Arf PF00025.16 ETO19345.1 - 0.073 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Secretin_N_2 PF07655.8 ETO19345.1 - 0.5 10.7 11.7 0.84 10.0 8.1 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain FimP PF09766.4 ETO19345.1 - 0.5 9.3 6.9 0.67 8.9 4.8 1.1 1 0 0 1 1 1 0 Fms-interacting protein VPS9 PF02204.13 ETO19346.1 - 7.9e-13 48.3 0.3 2.1e-12 46.9 0.0 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Peptidase_S49_N PF08496.5 ETO19346.1 - 0.011 15.5 1.1 0.019 14.7 0.8 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RCR PF12273.3 ETO19346.1 - 0.012 16.1 0.1 0.021 15.4 0.1 1.4 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Shisa PF13908.1 ETO19346.1 - 0.035 14.2 0.1 0.059 13.5 0.1 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator MLANA PF14991.1 ETO19346.1 - 0.12 12.4 0.2 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein melan-A DUF2500 PF10694.4 ETO19346.1 - 4.1 7.4 6.7 10 6.1 4.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2500) PaaA_PaaC PF05138.7 ETO19347.1 - 0.0047 15.9 1.0 0.0055 15.7 0.7 1.2 1 0 0 1 1 1 1 Phenylacetic acid catabolic protein Peptidase_S49_N PF08496.5 ETO19347.1 - 0.33 10.7 2.9 0.57 9.9 0.5 1.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal IncA PF04156.9 ETO19348.1 - 0.0072 15.9 14.2 0.092 12.3 0.1 2.1 2 0 0 2 2 2 1 IncA protein CENP-F_leu_zip PF10473.4 ETO19348.1 - 0.014 15.2 2.7 0.014 15.2 1.9 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 ETO19348.1 - 0.034 13.9 24.6 0.045 13.5 10.1 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein HAUS-augmin3 PF14932.1 ETO19348.1 - 0.29 10.3 17.2 0.31 10.2 7.2 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF4618 PF15397.1 ETO19348.1 - 0.35 10.1 20.3 0.91 8.7 7.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) DUF724 PF05266.9 ETO19348.1 - 0.49 9.9 21.0 0.27 10.8 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Pox_A_type_inc PF04508.7 ETO19348.1 - 0.51 10.2 27.8 1.2 9.1 3.2 4.7 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DUF2968 PF11180.3 ETO19348.1 - 1.2 8.4 19.6 0.5 9.7 8.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Mnd1 PF03962.10 ETO19348.1 - 1.8 8.2 21.3 2.7 7.6 1.0 2.2 2 0 0 2 2 2 0 Mnd1 family APG6 PF04111.7 ETO19348.1 - 1.9 7.4 22.1 0.76 8.7 9.7 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 Fzo_mitofusin PF04799.8 ETO19348.1 - 2.9 7.2 11.6 4.6 6.5 0.1 2.3 2 0 0 2 2 2 0 fzo-like conserved region OmpH PF03938.9 ETO19348.1 - 2.9 7.8 22.2 3.9 7.3 9.3 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) GAS PF13851.1 ETO19348.1 - 4.8 6.3 31.1 4.1 6.5 12.4 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding HrpB7 PF09486.5 ETO19348.1 - 5.2 6.9 14.1 1.1 9.1 5.5 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF4407 PF14362.1 ETO19348.1 - 5.2 5.9 15.4 1.7 7.4 5.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF2051 PF09738.4 ETO19348.1 - 6.9 5.8 20.7 3 7.0 6.2 2.1 2 0 0 2 2 2 0 Double stranded RNA binding protein (DUF2051) Striatin PF08232.7 ETO19348.1 - 8 6.7 25.3 1.4 9.2 8.2 2.9 2 1 1 3 3 3 0 Striatin family ADIP PF11559.3 ETO19348.1 - 9 6.1 31.1 2.7 7.8 1.7 2.6 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding TMPIT PF07851.8 ETO19348.1 - 9.7 5.1 14.6 6.2 5.7 0.5 2.1 2 0 0 2 2 2 0 TMPIT-like protein FH2 PF02181.18 ETO19350.1 - 3.4e-06 26.1 6.9 5.6e-06 25.4 4.5 1.5 1 1 1 2 2 2 1 Formin Homology 2 Domain DUF2360 PF10152.4 ETO19350.1 - 6.4e-06 26.5 1.3 0.0058 16.9 0.0 2.3 2 0 0 2 2 2 2 Predicted coiled-coil domain-containing protein (DUF2360) WD40 PF00400.27 ETO19351.1 - 1e-08 34.6 0.8 0.0013 18.5 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat Filament PF00038.16 ETO19351.1 - 2.5 7.4 134.3 0.073 12.5 56.9 6.4 2 1 3 5 5 5 0 Intermediate filament protein Methyltransf_PK PF05891.7 ETO19352.1 - 9.8e-33 113.2 0.3 1.1e-32 113.0 0.2 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 ETO19352.1 - 0.0011 18.6 0.1 0.0037 16.9 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETO19352.1 - 0.0051 17.1 0.1 0.0084 16.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO19352.1 - 0.0081 16.6 0.0 0.014 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain mRNA_stabil PF13929.1 ETO19352.1 - 0.011 14.7 1.0 0.013 14.4 0.7 1.1 1 0 0 1 1 1 0 mRNA stabilisation Methyltransf_11 PF08241.7 ETO19352.1 - 0.046 14.2 0.0 0.076 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Sec1 PF00995.18 ETO19353.1 - 1.8e-37 129.2 1.5 2.3e-37 128.9 1.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF3699 PF12480.3 ETO19353.1 - 0.064 12.9 0.1 0.7 9.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3699) Peptidase_C1 PF00112.18 ETO19354.1 - 2.8e-65 220.2 16.5 3.4e-65 220.0 11.5 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 ETO19354.1 - 2.8e-07 29.4 1.0 0.00042 18.9 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Cofilin_ADF PF00241.15 ETO19355.1 - 1.5e-18 66.9 2.4 5.1e-09 36.0 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein WRKY PF03106.10 ETO19355.1 - 0.011 15.5 0.2 0.15 11.9 0.0 2.5 2 0 0 2 2 2 0 WRKY DNA -binding domain TLD PF07534.11 ETO19356.1 - 5.6e-28 97.6 0.0 1.3e-27 96.4 0.0 1.7 1 0 0 1 1 1 1 TLD CALCOCO1 PF07888.6 ETO19356.1 - 0.0028 16.0 20.1 0.0028 16.0 13.9 3.1 2 1 1 3 3 3 2 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2688 PF10892.3 ETO19356.1 - 0.057 13.0 0.2 13 5.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) Reo_sigmaC PF04582.7 ETO19356.1 - 0.78 8.8 22.7 0.38 9.8 0.9 3.6 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Inhibitor_I29 PF08246.7 ETO19357.1 - 4.9e-12 45.9 2.8 8.5e-12 45.1 2.0 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) ABC_membrane PF00664.18 ETO19357.1 - 0.00055 19.4 0.2 0.00078 18.9 0.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region Peptidase_M75 PF09375.5 ETO19358.1 - 0.0023 17.2 0.5 0.003 16.8 0.3 1.2 1 0 0 1 1 1 1 Imelysin Hid1 PF12722.2 ETO19358.1 - 0.0083 13.8 4.1 0.0094 13.6 2.8 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.11 ETO19358.1 - 0.016 15.0 2.7 0.024 14.5 1.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PA-IIL PF07472.6 ETO19358.1 - 0.033 14.3 0.6 0.084 13.0 0.4 1.6 1 0 0 1 1 1 0 Fucose-binding lectin II (PA-IIL) DUF2064 PF09837.4 ETO19358.1 - 0.073 12.6 0.2 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2064) Secretin_N_2 PF07655.8 ETO19358.1 - 0.078 13.3 2.9 0.18 12.1 2.0 1.8 1 1 0 1 1 1 0 Secretin N-terminal domain DUF2868 PF11067.3 ETO19358.1 - 0.093 11.8 0.1 0.16 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Pkinase PF00069.20 ETO19359.1 - 3e-05 23.2 0.1 5.4e-05 22.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO19359.1 - 0.00073 18.6 0.0 0.00082 18.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PDDEXK_1 PF12705.2 ETO19360.1 - 0.0022 17.4 0.1 0.0027 17.1 0.1 1.1 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily NACHT PF05729.7 ETO19360.1 - 0.0025 17.5 0.0 0.0045 16.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETO19360.1 - 0.0037 17.3 0.0 0.0071 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO19360.1 - 0.0047 17.7 0.1 0.027 15.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETO19360.1 - 0.0055 17.0 0.3 0.048 13.9 0.0 2.3 1 1 1 2 2 2 1 AAA domain UPF0079 PF02367.12 ETO19360.1 - 0.037 13.6 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 ETO19360.1 - 0.049 12.7 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF258 PF03193.11 ETO19360.1 - 0.071 12.3 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PPV_E1_C PF00519.12 ETO19360.1 - 0.086 11.4 0.0 0.097 11.2 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase MobB PF03205.9 ETO19360.1 - 0.1 12.3 0.2 4.5 6.9 0.0 2.3 1 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 ETO19360.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 ETO19360.1 - 0.12 12.6 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 ETO19360.1 - 1 8.7 5.9 4.9 6.4 1.0 2.4 1 1 1 2 2 2 0 AAA-like domain Helicase_C PF00271.26 ETO19362.1 - 7.2e-24 83.4 0.0 3.9e-23 81.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETO19362.1 - 1.5e-08 34.3 0.0 6.7e-08 32.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Macoilin PF09726.4 ETO19363.1 - 0.023 12.9 27.9 0.027 12.7 19.3 1.0 1 0 0 1 1 1 0 Transmembrane protein LLC1 PF14945.1 ETO19363.1 - 0.13 12.5 7.4 0.22 11.8 5.2 1.4 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Spt5_N PF11942.3 ETO19363.1 - 0.28 11.8 4.7 0.54 10.9 3.2 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Borrelia_P83 PF05262.6 ETO19363.1 - 0.86 7.7 9.3 0.97 7.6 6.5 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF3439 PF11921.3 ETO19363.1 - 0.89 9.3 5.3 0.18 11.5 1.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) PAT1 PF09770.4 ETO19363.1 - 1.1 7.4 20.7 1.3 7.2 14.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4613 PF15390.1 ETO19363.1 - 1.8 6.6 10.6 2.1 6.3 7.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Dicty_REP PF05086.7 ETO19363.1 - 3.5 5.2 12.7 4.3 4.9 8.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Peptidase_S49_N PF08496.5 ETO19363.1 - 7.8 6.2 8.9 0.78 9.5 2.8 1.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal RCC1 PF00415.13 ETO19364.1 - 9.8e-24 83.3 0.4 2.5e-13 50.0 0.0 3.7 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO19364.1 - 6.3e-15 54.3 2.0 8.4e-05 22.0 0.1 4.0 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat CENP-B_dimeris PF09026.5 ETO19364.1 - 0.25 11.6 8.3 0.8 9.9 0.0 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain FNIP_N PF14636.1 ETO19364.1 - 4 7.9 9.1 0.57 10.6 3.1 2.1 2 1 0 2 2 2 0 Folliculin-interacting protein N-terminus Myc_N PF01056.13 ETO19364.1 - 8.3 5.4 14.5 0.022 13.9 3.3 1.6 2 0 0 2 2 2 0 Myc amino-terminal region Cullin PF00888.17 ETO19365.1 - 3.9e-16 58.7 2.4 4.1e-16 58.6 1.7 1.0 1 0 0 1 1 1 1 Cullin family GPI-anchored PF10342.4 ETO19366.1 - 0.022 15.2 1.0 0.052 14.0 0.0 2.0 2 0 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SRP54 PF00448.17 ETO19367.1 - 2.4e-54 183.7 1.4 4.9e-54 182.7 0.9 1.5 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_22 PF13401.1 ETO19367.1 - 4.9e-08 33.1 0.0 8.7e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 ETO19367.1 - 3.2e-07 30.2 0.2 0.00019 21.1 0.1 2.4 1 1 0 1 1 1 1 NTPase AAA_16 PF13191.1 ETO19367.1 - 1.8e-06 28.0 0.2 3.9e-06 26.9 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.1 ETO19367.1 - 2e-06 27.5 0.2 4.6e-06 26.3 0.2 1.5 1 1 1 2 2 2 1 AAA domain CbiA PF01656.18 ETO19367.1 - 6.3e-06 25.7 0.5 1.9e-05 24.1 0.3 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 ETO19367.1 - 3.8e-05 23.4 0.1 0.0014 18.3 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 ETO19367.1 - 0.00011 21.1 0.2 0.00033 19.5 0.1 1.9 2 1 0 2 2 2 1 ArgK protein AAA PF00004.24 ETO19367.1 - 0.00028 21.0 0.0 0.00054 20.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.12 ETO19367.1 - 0.00047 19.7 0.2 0.012 15.2 0.1 2.1 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 ETO19367.1 - 0.00062 19.7 0.1 0.0011 18.9 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DAP3 PF10236.4 ETO19367.1 - 0.003 16.5 0.0 0.005 15.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_14 PF13173.1 ETO19367.1 - 0.0055 16.6 0.0 0.012 15.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETO19367.1 - 0.0077 16.1 0.1 0.013 15.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain DUF77 PF01910.12 ETO19367.1 - 0.0078 15.8 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF77 AAA_28 PF13521.1 ETO19367.1 - 0.0091 15.9 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 ETO19367.1 - 0.011 14.7 0.1 0.014 14.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.14 ETO19367.1 - 0.015 14.7 0.7 0.038 13.4 0.5 1.7 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Glyco_trans_4_2 PF13477.1 ETO19367.1 - 0.027 14.3 0.0 0.79 9.5 0.0 2.3 1 1 0 1 1 1 0 Glycosyl transferase 4-like AAA_10 PF12846.2 ETO19367.1 - 0.033 13.6 0.1 0.05 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain NACHT PF05729.7 ETO19367.1 - 0.036 13.7 0.0 0.1 12.2 0.0 1.8 1 1 0 1 1 1 0 NACHT domain DUF258 PF03193.11 ETO19367.1 - 0.041 13.0 0.0 0.11 11.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 PIG-L PF02585.12 ETO19367.1 - 0.062 13.8 0.1 0.12 12.9 0.1 1.4 1 0 0 1 1 1 0 GlcNAc-PI de-N-acetylase 6PF2K PF01591.13 ETO19367.1 - 0.07 12.1 0.1 0.1 11.6 0.1 1.4 1 1 0 1 1 1 0 6-phosphofructo-2-kinase KAP_NTPase PF07693.9 ETO19367.1 - 0.083 11.8 0.0 0.28 10.1 0.0 1.6 1 1 1 2 2 2 0 KAP family P-loop domain Zeta_toxin PF06414.7 ETO19367.1 - 0.093 11.8 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin YqgF PF14639.1 ETO19367.1 - 0.1 12.1 0.1 0.39 10.2 0.0 1.9 2 0 0 2 2 2 0 Holliday-junction resolvase-like of SPT6 ABC_tran PF00005.22 ETO19367.1 - 0.12 12.7 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 ETO19367.1 - 0.12 11.9 0.0 0.31 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain HSDR_N PF04313.9 ETO19367.1 - 0.12 12.0 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) EF-hand_6 PF13405.1 ETO19368.1 - 0.00022 20.8 0.2 0.006 16.3 0.0 3.2 4 0 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.1 ETO19368.1 - 0.013 15.6 0.2 0.013 15.6 0.1 2.7 3 1 0 3 3 3 0 EF-hand domain pair EF-hand_8 PF13833.1 ETO19368.1 - 0.06 12.9 1.3 0.084 12.5 0.1 1.9 2 0 0 2 2 2 0 EF-hand domain pair DUF3439 PF11921.3 ETO19368.1 - 0.091 12.5 0.5 0.15 11.7 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Gluconate_2-dh3 PF13618.1 ETO19368.1 - 0.12 12.5 4.5 0.072 13.2 1.0 2.0 1 1 1 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 DUF3482 PF11981.3 ETO19368.1 - 2.5 7.2 6.9 0.52 9.4 1.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3482) OmpH PF03938.9 ETO19368.1 - 2.6 7.9 8.6 32 4.4 6.0 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Cauli_AT PF03233.8 ETO19368.1 - 2.9 7.5 6.6 0.78 9.4 2.0 1.9 1 1 0 2 2 2 0 Aphid transmission protein Ank_2 PF12796.2 ETO19369.1 - 4.3e-24 84.6 1.7 2.4e-12 46.9 0.0 2.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO19369.1 - 9.8e-10 38.6 0.3 0.0013 19.2 0.0 2.9 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 ETO19369.1 - 2.3e-07 30.2 0.2 2.1e-05 24.1 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 ETO19369.1 - 2e-05 24.6 0.4 0.00091 19.4 0.0 3.1 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO19369.1 - 3.7e-05 23.5 0.9 0.073 13.3 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat FAM163 PF15069.1 ETO19370.1 - 3.3e-05 24.4 2.5 3.8e-05 24.2 1.8 1.1 1 0 0 1 1 1 1 FAM163 family Shisa PF13908.1 ETO19370.1 - 0.0041 17.3 1.1 0.0045 17.1 0.8 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator TMEM52 PF14979.1 ETO19370.1 - 0.072 12.9 1.0 0.08 12.8 0.7 1.2 1 0 0 1 1 1 0 Transmembrane 52 gpUL132 PF11359.3 ETO19370.1 - 0.28 10.4 4.0 0.32 10.2 2.8 1.4 1 1 0 1 1 1 0 Glycoprotein UL132 ETRAMP PF09716.5 ETO19370.1 - 2.7 8.0 5.3 7.5 6.5 3.7 1.8 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) EphA2_TM PF14575.1 ETO19370.1 - 4.3 7.8 4.8 1.6 9.1 1.7 1.6 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain V-SNARE PF05008.10 ETO19371.1 - 3.8e-08 33.3 2.2 3.8e-08 33.3 1.5 2.4 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 ETO19371.1 - 3.5e-07 30.1 1.6 9.1e-07 28.8 0.1 2.2 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus WEMBL PF05701.6 ETO19371.1 - 0.00011 20.8 15.9 0.00024 19.7 11.0 1.5 1 1 0 1 1 1 1 Weak chloroplast movement under blue light Sec20 PF03908.8 ETO19371.1 - 0.0009 18.8 2.0 0.27 10.9 0.0 2.6 2 1 0 2 2 2 2 Sec20 DUF1664 PF07889.7 ETO19371.1 - 0.018 14.8 6.2 0.79 9.5 0.3 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) Bcr-Abl_Oligo PF09036.5 ETO19371.1 - 0.086 12.8 1.6 1.3 9.0 0.2 2.6 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain T4SS PF07996.6 ETO19371.1 - 0.14 11.9 14.6 0.24 11.2 9.3 1.8 1 1 1 2 2 2 0 Type IV secretion system proteins DUF2730 PF10805.3 ETO19371.1 - 0.3 10.8 3.7 0.52 10.0 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) PilJ PF13675.1 ETO19371.1 - 0.38 11.0 6.8 14 6.0 4.7 2.8 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term YgaB PF14182.1 ETO19371.1 - 2.7 8.2 11.8 0.059 13.6 2.3 2.4 2 2 1 3 3 3 0 YgaB-like protein DUF2408 PF10303.4 ETO19371.1 - 3 7.9 12.2 0.047 13.7 1.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) Fib_alpha PF08702.5 ETO19371.1 - 4.1 7.5 15.2 0.069 13.2 2.5 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family CorA PF01544.13 ETO19371.1 - 6.5 5.7 8.8 55 2.6 6.1 2.1 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein PH PF00169.24 ETO19372.1 - 3.8e-11 43.1 0.3 3.8e-11 43.1 0.2 1.7 2 0 0 2 2 2 1 PH domain PH_3 PF14593.1 ETO19372.1 - 0.00011 21.9 1.6 0.0022 17.8 0.8 2.2 1 1 0 1 1 1 1 PH domain PH_8 PF15409.1 ETO19372.1 - 0.00015 21.7 1.4 0.00062 19.7 1.0 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain Mcp5_PH PF12814.2 ETO19372.1 - 0.08 12.8 1.3 0.11 12.3 0.7 1.6 1 1 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology PH_11 PF15413.1 ETO19372.1 - 0.76 10.0 9.1 0.55 10.4 2.1 2.8 1 1 1 2 2 2 0 Pleckstrin homology domain Spt5_N PF11942.3 ETO19373.1 - 0.0057 17.2 11.4 0.0078 16.8 7.9 1.3 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal Sigma70_ner PF04546.8 ETO19373.1 - 0.019 14.5 10.4 0.021 14.4 7.2 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop53 PF07767.6 ETO19373.1 - 0.031 13.2 8.2 0.037 13.0 5.7 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) alpha-hel2 PF14456.1 ETO19373.1 - 0.047 12.4 2.3 0.044 12.5 1.6 1.1 1 0 0 1 1 1 0 Alpha-helical domain 2 BSP_II PF05432.6 ETO19373.1 - 0.05 12.8 14.7 0.055 12.7 10.2 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CENP-B_dimeris PF09026.5 ETO19373.1 - 0.091 13.0 10.8 0.12 12.6 7.5 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nro1 PF12753.2 ETO19373.1 - 0.13 11.1 9.2 0.13 11.1 6.4 1.0 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 Radial_spoke PF04712.7 ETO19373.1 - 0.14 10.8 8.3 0.15 10.8 5.8 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein BMF PF15185.1 ETO19373.1 - 0.19 11.0 4.1 0.21 10.8 2.8 1.2 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis Nop14 PF04147.7 ETO19373.1 - 0.22 9.4 11.7 0.23 9.3 8.1 1.0 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.13 ETO19373.1 - 0.23 10.5 10.1 0.26 10.4 7.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Nucleoplasmin PF03066.10 ETO19373.1 - 0.34 10.4 14.8 0.52 9.8 10.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin Prp19_bind PF06991.6 ETO19373.1 - 0.44 9.7 13.8 0.53 9.5 9.6 1.1 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain Salp15 PF12115.3 ETO19373.1 - 0.68 10.1 3.0 0.76 10.0 2.1 1.1 1 0 0 1 1 1 0 Salivary protein of 15kDa inhibits CD4+ T cell activation Sporozoite_P67 PF05642.6 ETO19373.1 - 0.83 7.4 6.2 0.83 7.4 4.3 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2890 PF11081.3 ETO19373.1 - 0.98 9.4 10.7 1.2 9.2 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Daxx PF03344.10 ETO19373.1 - 1.1 7.6 13.8 1.3 7.4 9.6 1.1 1 0 0 1 1 1 0 Daxx Family TRAP_alpha PF03896.11 ETO19373.1 - 1.1 8.1 7.2 1.1 8.1 5.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit XAP5 PF04921.9 ETO19373.1 - 1.1 8.7 8.6 1.4 8.4 5.9 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator DUF3381 PF11861.3 ETO19373.1 - 1.2 8.6 12.2 1.5 8.2 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Adeno_terminal PF02459.10 ETO19373.1 - 1.2 7.2 7.5 1.3 7.0 5.2 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein VID27 PF08553.5 ETO19373.1 - 1.3 7.1 11.3 1.4 7.0 7.9 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein PI3K_1B_p101 PF10486.4 ETO19373.1 - 1.5 6.2 6.4 1.5 6.2 4.4 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pox_RNA_Pol_19 PF05320.7 ETO19373.1 - 2 8.1 15.3 3.5 7.3 10.6 1.4 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF4407 PF14362.1 ETO19373.1 - 2.4 7.0 5.0 2.6 6.8 3.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF506 PF04720.7 ETO19373.1 - 2.5 7.7 5.9 2.6 7.5 4.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Paf1 PF03985.8 ETO19373.1 - 3.1 6.4 13.5 3.5 6.2 9.3 1.0 1 0 0 1 1 1 0 Paf1 Pox_Ag35 PF03286.9 ETO19373.1 - 4.8 6.6 10.6 5.4 6.4 7.3 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.9 ETO19373.1 - 5 5.0 9.2 5.4 4.9 6.4 1.0 1 0 0 1 1 1 0 CDC45-like protein TEX19 PF15553.1 ETO19373.1 - 6.2 6.6 6.6 7.1 6.4 4.6 1.1 1 0 0 1 1 1 0 Testis-expressed protein 19 DUF4061 PF13270.1 ETO19373.1 - 6.4 6.9 10.6 0.76 9.9 3.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4061) Mito_fiss_reg PF05308.6 ETO19374.1 - 0.0015 17.9 2.5 0.0015 17.9 1.7 1.8 2 1 0 2 2 2 1 Mitochondrial fission regulator uDENN PF03456.13 ETO19377.1 - 0.00096 19.0 1.9 0.0072 16.2 0.4 2.7 2 1 0 2 2 2 1 uDENN domain ALIX_LYPXL_bnd PF13949.1 ETO19377.1 - 0.01 14.8 0.4 0.015 14.3 0.2 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Herpes_UL20 PF04544.7 ETO19377.1 - 0.017 14.9 5.9 0.025 14.4 4.1 1.3 1 0 0 1 1 1 0 Herpesvirus egress protein UL20 Spc7 PF08317.6 ETO19378.1 - 0.00079 18.1 11.3 0.001 17.8 7.8 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF3782 PF12644.2 ETO19378.1 - 0.0037 17.0 2.4 0.53 10.1 0.2 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3782) Syntaphilin PF15290.1 ETO19378.1 - 0.037 13.5 14.5 0.078 12.4 5.6 2.1 1 1 1 2 2 2 0 Golgi-localised syntaxin-1-binding clamp Filament PF00038.16 ETO19378.1 - 0.05 13.0 11.3 0.12 11.8 4.4 2.0 1 1 1 2 2 2 0 Intermediate filament protein RNase_T PF00929.19 ETO19378.1 - 0.066 13.4 0.1 0.099 12.9 0.1 1.3 1 0 0 1 1 1 0 Exonuclease DUF948 PF06103.6 ETO19378.1 - 0.12 12.2 3.6 0.22 11.4 2.5 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Lzipper-MIP1 PF14389.1 ETO19378.1 - 0.15 12.1 7.4 0.24 11.5 1.3 2.7 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 UBN2_3 PF14244.1 ETO19378.1 - 0.24 10.9 4.4 0.13 11.8 0.7 2.2 2 1 1 3 3 3 0 gag-polypeptide of LTR copia-type Pox_A_type_inc PF04508.7 ETO19378.1 - 0.25 11.2 2.6 14 5.8 0.0 3.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat ALMT PF11744.3 ETO19378.1 - 0.26 9.9 5.6 0.25 9.9 3.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF641 PF04859.7 ETO19378.1 - 0.29 10.8 7.1 0.57 9.9 4.9 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Tup_N PF08581.5 ETO19378.1 - 0.31 11.2 12.7 1 9.5 1.3 2.7 1 1 1 2 2 2 0 Tup N-terminal DUF3552 PF12072.3 ETO19378.1 - 0.6 9.2 12.8 0.18 11.0 7.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) SseC PF04888.7 ETO19378.1 - 1.1 8.4 5.3 1.7 7.9 3.6 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family ATG16 PF08614.6 ETO19378.1 - 1.3 8.8 14.6 0.051 13.3 5.0 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) MutS_IV PF05190.13 ETO19378.1 - 1.5 9.0 7.6 3.6 7.8 0.7 2.5 1 1 1 2 2 2 0 MutS family domain IV Seryl_tRNA_N PF02403.17 ETO19378.1 - 1.6 8.7 10.4 3.4 7.7 7.2 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 ETO19378.1 - 2.1 7.8 7.5 1.5 8.3 2.2 2.3 1 1 0 2 2 2 0 Septum formation initiator DUF4407 PF14362.1 ETO19378.1 - 2.9 6.7 6.2 7.4 5.4 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Med4 PF10018.4 ETO19378.1 - 3 7.1 13.0 0.1 12.0 4.0 2.3 2 1 1 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 V_ATPase_I PF01496.14 ETO19378.1 - 3.7 5.2 8.0 4 5.1 5.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4315 PF14193.1 ETO19378.1 - 4.9 7.1 10.5 0.4 10.6 1.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) CCDC92 PF14916.1 ETO19378.1 - 5.4 6.6 10.0 3 7.5 2.8 2.8 1 1 1 2 2 2 0 Coiled-coil domain of unknown function IncA PF04156.9 ETO19378.1 - 5.5 6.5 10.6 7.2 6.1 6.8 1.6 1 1 0 1 1 1 0 IncA protein ACCA PF03255.9 ETO19378.1 - 6.3 6.3 7.9 9.1 5.8 1.6 2.3 1 1 2 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF342 PF03961.8 ETO19378.1 - 6.6 5.0 8.4 8.5 4.6 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) WD40 PF00400.27 ETO19380.1 - 1e-58 193.2 15.6 2.7e-12 46.0 0.2 6.3 5 1 1 6 6 6 5 WD domain, G-beta repeat Nbas_N PF15492.1 ETO19380.1 - 2.8e-05 23.3 2.2 0.061 12.4 0.0 3.9 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 ETO19380.1 - 9.4e-05 21.9 10.7 10 5.8 0.0 5.7 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO19380.1 - 0.00012 20.3 2.5 0.32 9.0 0.0 3.6 2 2 1 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO19380.1 - 0.0009 18.0 4.3 0.27 9.9 0.2 2.8 1 1 1 2 2 2 2 Nup133 N terminal like DPPIV_N PF00930.16 ETO19380.1 - 0.0092 14.5 0.1 11 4.4 0.0 3.8 2 1 2 4 4 4 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region BBS2_Mid PF14783.1 ETO19380.1 - 0.044 13.5 0.7 36 4.1 0.0 4.2 2 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region TolB_N PF04052.8 ETO19380.1 - 0.081 13.0 0.0 53 3.9 0.0 3.9 4 0 0 4 4 4 0 TolB amino-terminal domain Proteasome_A_N PF10584.4 ETO19380.1 - 2.7 7.3 11.7 8.8 5.7 0.0 5.1 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Rtf2 PF04641.7 ETO19381.1 - 2.1 7.4 11.8 2.5 7.2 8.2 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger RR_TM4-6 PF06459.7 ETO19381.1 - 2.8 7.7 14.3 3.9 7.2 9.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Senescence_reg PF04520.8 ETO19381.1 - 3.1 8.2 11.1 4.7 7.7 7.7 1.2 1 0 0 1 1 1 0 Senescence regulator DUF3807 PF12720.2 ETO19381.1 - 6.8 6.8 15.5 8.9 6.4 10.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Adaptin_binding PF10199.4 ETO19381.1 - 8.2 6.7 22.9 1.5 9.1 13.4 1.5 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Secretin_N_2 PF07655.8 ETO19382.1 - 8.4 6.8 25.8 13 6.2 1.7 2.8 2 0 0 2 2 2 0 Secretin N-terminal domain PK_C PF02887.11 ETO19383.1 - 3.9e-13 48.9 0.0 7.6e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain DUF4154 PF13689.1 ETO19383.1 - 0.11 12.0 0.1 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4154) Ribosomal_60s PF00428.14 ETO19383.1 - 8 6.9 7.3 1e+02 3.3 5.5 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF2201_N PF13203.1 ETO19384.1 - 2.4 7.2 15.9 2.8 7.0 11.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Pilt PF15453.1 ETO19384.1 - 8.2 6.0 20.9 8.6 5.9 14.2 1.2 1 1 0 1 1 1 0 Protein incorporated later into Tight Junctions GatB_Yqey PF02637.13 ETO19385.1 - 0.022 14.4 8.6 0.075 12.7 2.3 2.2 2 0 0 2 2 2 0 GatB domain SOBP PF15279.1 ETO19385.1 - 0.069 13.5 2.6 0.087 13.1 1.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein MSC PF09402.5 ETO19385.1 - 0.41 9.2 7.1 0.59 8.7 4.9 1.3 1 1 0 1 1 1 0 Man1-Src1p-C-terminal domain DUF3439 PF11921.3 ETO19387.1 - 0.087 12.5 7.3 1.9 8.2 5.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF1880 PF08976.6 ETO19387.1 - 0.5 10.5 4.4 0.44 10.6 1.2 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1880) MIP-T3 PF10243.4 ETO19387.1 - 1.1 7.6 38.9 1.2 7.5 27.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 LMBR1 PF04791.11 ETO19387.1 - 5.2 5.5 14.3 2.1e+02 0.2 9.9 2.2 1 1 0 1 1 1 0 LMBR1-like membrane protein SR-25 PF10500.4 ETO19388.1 - 0.19 11.1 16.5 0.2 11.0 11.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BRF1 PF07741.8 ETO19388.1 - 2.8 8.2 12.3 3.5 7.9 8.5 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain YL1 PF05764.8 ETO19388.1 - 3.2 7.2 14.3 3.5 7.1 9.9 1.1 1 0 0 1 1 1 0 YL1 nuclear protein XK-related PF09815.4 ETO19389.1 - 3.2e-07 29.6 8.2 5.2e-07 28.9 5.7 1.3 1 0 0 1 1 1 1 XK-related protein Ank_2 PF12796.2 ETO19391.1 - 4.2e-20 71.8 2.3 1.6e-07 31.5 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO19391.1 - 8.7e-20 70.7 0.7 2.1e-05 24.8 0.0 3.9 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 ETO19391.1 - 1.6e-17 62.3 0.3 0.031 14.1 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 ETO19391.1 - 7.7e-12 44.2 0.8 0.56 10.6 0.0 5.8 6 1 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 ETO19391.1 - 1.7e-11 43.9 2.6 0.0045 17.2 0.1 4.5 2 1 3 5 5 5 4 Ankyrin repeats (many copies) AA_permease PF00324.16 ETO19392.1 - 8.7e-23 80.3 6.8 9.5e-19 67.0 5.7 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 ETO19392.1 - 1.6e-12 46.7 8.4 2.1e-12 46.3 5.9 1.1 1 0 0 1 1 1 1 Amino acid permease Parvo_NS1 PF01057.12 ETO19392.1 - 0.094 11.5 0.1 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PNRC PF15365.1 ETO19394.1 - 0.014 15.3 0.0 0.1 12.6 0.1 2.2 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator Phage_int_SAM_5 PF13102.1 ETO19394.1 - 0.65 10.0 4.8 0.75 9.7 2.6 1.4 1 1 0 1 1 1 0 Phage integrase SAM-like domain Codanin-1_C PF15296.1 ETO19395.1 - 0.0077 16.0 0.0 0.032 14.1 0.0 2.1 1 0 0 1 1 1 1 Codanin-1 C-terminus CAS_CSE1 PF03378.10 ETO19395.1 - 0.016 13.5 2.1 0.64 8.2 0.6 2.3 2 0 0 2 2 2 0 CAS/CSE protein, C-terminus AMP-binding PF00501.23 ETO19396.1 - 5.1e-14 51.5 4.7 9.1e-11 40.7 0.6 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 ETO19396.1 - 2.4e-08 34.7 0.5 5.8e-08 33.5 0.3 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Mem_trans PF03547.13 ETO19397.1 - 0.011 14.0 0.0 0.016 13.5 0.0 1.2 1 0 0 1 1 1 0 Membrane transport protein FAM176 PF14851.1 ETO19397.1 - 0.1 12.3 0.4 0.2 11.3 0.3 1.4 1 0 0 1 1 1 0 FAM176 family DUF2972 PF11186.3 ETO19398.1 - 0.049 13.5 0.2 0.072 12.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) TFCD_C PF12612.3 ETO19399.1 - 0.036 13.4 2.5 0.08 12.3 0.7 2.3 2 1 1 3 3 3 0 Tubulin folding cofactor D C terminal DUF334 PF03904.8 ETO19399.1 - 0.098 11.9 0.7 0.8 8.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF334) MMS19_C PF12460.3 ETO19400.1 - 0.038 12.7 0.3 0.06 12.0 0.2 1.3 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal Cytadhesin_P30 PF07271.6 ETO19404.1 - 0.081 12.1 0.2 0.083 12.1 0.1 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 Peroxin-13_N PF04088.8 ETO19404.1 - 0.085 12.8 0.6 0.17 11.7 0.4 1.7 1 1 0 1 1 1 0 Peroxin 13, N-terminal region EF-hand_6 PF13405.1 ETO19406.1 - 0.032 14.0 0.2 6 7.0 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain EF-hand_8 PF13833.1 ETO19406.1 - 0.048 13.2 0.5 30 4.3 0.0 3.5 3 1 0 3 3 3 0 EF-hand domain pair UPF0278 PF08745.6 ETO19406.1 - 0.057 12.6 0.5 0.065 12.4 0.4 1.1 1 0 0 1 1 1 0 UPF0278 family EF-hand_1 PF00036.27 ETO19406.1 - 0.072 12.4 0.1 17 4.9 0.0 2.9 2 0 0 2 2 2 0 EF hand Sensor PF13796.1 ETO19407.1 - 0.00048 19.7 0.4 0.013 15.1 0.0 2.2 2 0 0 2 2 2 1 Putative sensor PP_kinase_C PF13090.1 ETO19407.1 - 0.062 11.8 0.1 0.091 11.3 0.0 1.1 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain DUF4533 PF15047.1 ETO19408.1 - 0.0025 17.2 0.2 0.0026 17.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4533) DBR1 PF05011.8 ETO19408.1 - 0.025 14.4 1.0 0.029 14.2 0.7 1.1 1 0 0 1 1 1 0 Lariat debranching enzyme, C-terminal domain MmgE_PrpD PF03972.9 ETO19408.1 - 0.076 11.1 0.3 0.094 10.8 0.2 1.1 1 0 0 1 1 1 0 MmgE/PrpD family G-patch PF01585.18 ETO19409.1 - 3.1e-10 39.6 0.4 5e-10 39.0 0.3 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 ETO19409.1 - 0.0074 16.1 0.1 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 DExH-box splicing factor binding site DUF4258 PF14076.1 ETO19409.1 - 0.073 13.0 0.5 3.2 7.8 0.3 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4258) Acyl_transf_3 PF01757.17 ETO19410.1 - 3e-05 23.0 6.6 3e-05 23.0 4.6 2.1 2 0 0 2 2 2 1 Acyltransferase family JmjC PF02373.17 ETO19413.1 - 4.5e-30 104.2 0.2 8.1e-30 103.3 0.1 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase DUF912 PF06024.7 ETO19414.1 - 0.081 12.9 0.0 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4505 PF14956.1 ETO19415.1 - 3.4e-30 105.0 2.5 7.5e-16 58.3 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4505) WD40 PF00400.27 ETO19416.1 - 6.6e-63 206.5 19.4 1.5e-11 43.6 1.2 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO19416.1 - 2.3e-09 35.9 5.9 0.0006 18.0 0.1 5.4 2 1 3 5 5 5 4 Nucleoporin Nup120/160 Methyltransf_25 PF13649.1 ETO19416.1 - 0.013 15.8 0.0 3.8 7.9 0.0 3.6 4 0 0 4 4 4 0 Methyltransferase domain DUF1900 PF08954.6 ETO19416.1 - 0.052 13.0 0.3 6.8 6.2 0.0 3.6 4 1 1 5 5 5 0 Domain of unknown function (DUF1900) Gal_Lectin PF02140.13 ETO19417.1 - 0.00032 20.9 0.6 0.00032 20.9 0.4 1.8 2 0 0 2 2 2 1 Galactose binding lectin domain Ion_trans_2 PF07885.11 ETO19418.1 - 2e-06 27.3 7.6 2e-06 27.3 5.3 2.9 2 1 0 2 2 2 1 Ion channel Ion_trans_N PF08412.5 ETO19418.1 - 0.00011 21.4 0.9 0.00011 21.4 0.6 2.3 2 1 1 3 3 3 1 Ion transport protein N-terminal TMEM154 PF15102.1 ETO19422.1 - 0.064 12.9 0.2 0.087 12.5 0.2 1.3 1 0 0 1 1 1 0 TMEM154 protein family Dicty_REP PF05086.7 ETO19422.1 - 0.12 10.1 7.6 0.11 10.1 5.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 ETO19422.1 - 0.32 10.7 10.3 0.39 10.4 7.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein MSC PF09402.5 ETO19426.1 - 0.96 8.0 13.7 1.5 7.4 9.5 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain LMBR1 PF04791.11 ETO19426.1 - 2.1 6.8 9.9 2.3 6.6 6.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Ndc1_Nup PF09531.5 ETO19426.1 - 8.5 4.6 8.9 11 4.2 6.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4476 PF14771.1 ETO19427.1 - 0.31 11.1 0.2 0.31 11.1 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4476) DUF2645 PF10840.3 ETO19427.1 - 0.5 10.5 4.3 0.49 10.5 1.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2645) CENP-F_leu_zip PF10473.4 ETO19428.1 - 9.5e-06 25.5 33.7 0.00035 20.4 3.1 3.8 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 ETO19428.1 - 1.9e-05 24.3 8.6 1.9e-05 24.3 5.9 2.5 1 1 1 2 2 2 1 IncA protein Filament PF00038.16 ETO19428.1 - 8e-05 22.2 35.0 0.0039 16.7 3.8 3.5 1 1 2 3 3 3 2 Intermediate filament protein ADIP PF11559.3 ETO19428.1 - 0.00022 21.1 7.6 0.00022 21.1 5.3 3.8 2 1 2 4 4 4 1 Afadin- and alpha -actinin-Binding CENP-Q PF13094.1 ETO19428.1 - 0.0013 18.7 11.5 0.0013 18.7 8.0 3.3 2 2 1 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit EzrA PF06160.7 ETO19428.1 - 0.0019 16.5 5.7 0.0019 16.5 3.9 2.8 2 1 1 3 3 3 1 Septation ring formation regulator, EzrA BicD PF09730.4 ETO19428.1 - 0.0021 16.4 2.6 0.0021 16.4 1.8 2.7 2 1 1 3 3 3 1 Microtubule-associated protein Bicaudal-D TPR_MLP1_2 PF07926.7 ETO19428.1 - 0.0025 17.5 11.9 0.0025 17.5 8.3 3.1 1 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein DUF1664 PF07889.7 ETO19428.1 - 0.0029 17.4 4.2 0.0029 17.4 2.9 3.4 1 1 0 2 2 2 1 Protein of unknown function (DUF1664) Pox_A_type_inc PF04508.7 ETO19428.1 - 0.0031 17.1 6.3 1.3 9.0 0.2 5.0 4 0 0 4 4 4 1 Viral A-type inclusion protein repeat Tup_N PF08581.5 ETO19428.1 - 0.0043 17.2 29.8 0.14 12.3 1.6 4.0 4 0 0 4 4 3 2 Tup N-terminal THOC7 PF05615.8 ETO19428.1 - 0.0052 17.0 32.9 0.025 14.8 1.0 3.6 1 1 2 3 3 3 1 Tho complex subunit 7 Myosin_tail_1 PF01576.14 ETO19428.1 - 0.0057 14.4 34.4 0.0089 13.8 23.8 1.2 1 0 0 1 1 1 1 Myosin tail Spc7 PF08317.6 ETO19428.1 - 0.0062 15.2 2.7 0.0062 15.2 1.9 3.0 1 1 2 3 3 2 1 Spc7 kinetochore protein PspA_IM30 PF04012.7 ETO19428.1 - 0.0092 15.3 27.5 0.086 12.1 6.7 2.8 1 1 1 2 2 2 1 PspA/IM30 family DUF3584 PF12128.3 ETO19428.1 - 0.015 12.6 31.7 0.032 11.5 22.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PMEI PF04043.10 ETO19428.1 - 0.017 14.9 4.2 1 9.2 0.1 2.4 1 1 1 2 2 2 0 Plant invertase/pectin methylesterase inhibitor Cast PF10174.4 ETO19428.1 - 0.019 13.0 32.4 0.94 7.4 22.7 2.9 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Fork_head_N PF08430.7 ETO19428.1 - 0.028 14.8 22.7 0.068 13.5 15.7 1.7 1 0 0 1 1 1 0 Forkhead N-terminal region Reo_sigmaC PF04582.7 ETO19428.1 - 0.037 13.2 4.4 0.093 11.8 1.3 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 ETO19428.1 - 0.038 13.8 13.7 1.5 8.6 1.5 3.5 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin PF00261.15 ETO19428.1 - 0.054 12.5 29.2 0.1 11.6 20.2 1.5 1 0 0 1 1 1 0 Tropomyosin DinB_2 PF12867.2 ETO19428.1 - 0.063 13.6 1.2 0.43 10.9 0.7 2.3 1 1 0 1 1 1 0 DinB superfamily CAP PF00188.21 ETO19428.1 - 0.11 12.9 6.0 0.055 13.9 1.4 2.2 2 0 0 2 2 2 0 Cysteine-rich secretory protein family FlaC_arch PF05377.6 ETO19428.1 - 0.81 9.6 17.5 2.4 8.0 0.0 5.0 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) Herpes_U30 PF04523.8 ETO19428.1 - 1.1 6.6 11.8 0.62 7.4 6.6 1.7 1 1 0 1 1 1 0 Herpes virus tegument protein U30 Acyl-CoA_dh_C PF12806.2 ETO19428.1 - 1.2 9.0 8.2 3.7 7.4 0.7 3.3 2 1 1 3 3 3 0 Acetyl-CoA dehydrogenase C-terminal like NPV_P10 PF05531.7 ETO19428.1 - 1.3 9.3 16.7 30 4.9 1.5 4.7 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Rab5-bind PF09311.6 ETO19428.1 - 1.6 8.5 34.7 1.7 8.4 9.6 2.7 2 1 0 2 2 2 0 Rabaptin-like protein FUSC PF04632.7 ETO19428.1 - 1.9 6.8 9.1 1.1 7.6 4.7 1.5 1 1 1 2 2 2 0 Fusaric acid resistance protein family Seryl_tRNA_N PF02403.17 ETO19428.1 - 2 8.4 36.6 0.44 10.5 3.3 4.6 2 1 3 5 5 5 0 Seryl-tRNA synthetase N-terminal domain V_ATPase_I PF01496.14 ETO19428.1 - 2.1 6.1 21.3 0.71 7.6 3.0 2.4 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Kinesin-relat_1 PF12711.2 ETO19428.1 - 2.2 8.7 22.0 3.1 8.2 6.0 4.0 2 1 0 3 3 3 0 Kinesin motor HALZ PF02183.13 ETO19428.1 - 2.6 7.8 17.6 0.6 9.8 0.5 4.1 3 2 2 5 5 4 0 Homeobox associated leucine zipper TraC PF07820.7 ETO19428.1 - 2.9 8.1 10.3 0.61 10.3 0.1 4.2 3 2 1 4 4 4 0 TraC-like protein DUF465 PF04325.8 ETO19428.1 - 3.1 7.5 12.9 1.3 8.8 0.6 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF465) DUF3450 PF11932.3 ETO19428.1 - 3.3 6.9 31.5 0.33 10.1 8.0 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) MAD PF05557.8 ETO19428.1 - 4.9 5.1 34.8 86 1.0 24.4 2.1 1 1 0 1 1 1 0 Mitotic checkpoint protein FHIPEP PF00771.15 ETO19428.1 - 5.1 5.2 16.8 0.0068 14.7 3.0 2.0 1 1 1 2 2 1 0 FHIPEP family TMF_TATA_bd PF12325.3 ETO19428.1 - 5.4 6.7 31.8 8.3 6.1 7.3 4.1 1 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF632 PF04782.7 ETO19429.1 - 0.014 14.5 0.2 0.014 14.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF632) Phage_GP20 PF06810.6 ETO19429.1 - 0.02 14.3 1.5 0.02 14.3 1.0 2.4 2 1 0 2 2 2 0 Phage minor structural protein GP20 zf-C2H2 PF00096.21 ETO19432.1 - 2.3e-14 52.7 71.0 0.00037 20.6 2.5 7.3 8 0 0 8 8 7 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETO19432.1 - 2.6e-13 49.5 59.7 0.00023 21.2 3.4 8.0 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2_4 PF13894.1 ETO19432.1 - 1e-09 38.0 52.3 0.0032 17.6 1.1 7.8 8 0 0 8 8 8 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 ETO19432.1 - 0.0001 22.3 48.2 0.028 14.5 0.7 7.5 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 ETO19432.1 - 0.00035 20.3 35.5 0.017 15.0 0.6 7.1 7 0 0 7 7 7 3 C2H2-type zinc finger zf-met PF12874.2 ETO19432.1 - 0.0063 16.6 42.1 0.04 14.1 0.1 7.3 6 1 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 ETO19432.1 - 0.028 14.5 1.1 0.028 14.5 0.8 6.0 2 2 4 6 6 6 0 C2H2 type zinc-finger (2 copies) IncA PF04156.9 ETO19432.1 - 0.061 12.9 3.2 0.11 12.0 2.2 1.4 1 0 0 1 1 1 0 IncA protein Tup_N PF08581.5 ETO19432.1 - 0.23 11.6 7.0 0.063 13.4 1.2 2.4 1 1 1 2 2 2 0 Tup N-terminal Rotamase PF00639.16 ETO19432.1 - 0.43 11.3 2.6 0.43 11.3 0.7 1.8 2 0 0 2 2 1 0 PPIC-type PPIASE domain Bap31 PF05529.7 ETO19432.1 - 0.47 9.8 5.3 1.2 8.6 3.7 1.7 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like zinc_ribbon_4 PF13717.1 ETO19432.1 - 4.7 6.9 28.3 7.5 6.3 4.4 5.4 4 1 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 ETO19432.1 - 7.2 6.2 28.4 10 5.8 4.4 5.4 4 1 0 4 4 4 0 zinc-ribbon domain Secretin_N_2 PF07655.8 ETO19434.1 - 0.25 11.7 20.3 0.52 10.7 14.0 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain Pex14_N PF04695.8 ETO19434.1 - 0.31 11.0 2.3 0.47 10.4 1.6 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RPOL_N PF14700.1 ETO19435.1 - 0.00054 19.3 0.2 0.00054 19.3 0.1 3.8 2 1 1 3 3 3 2 DNA-directed RNA polymerase N-terminal TFIIA PF03153.8 ETO19436.1 - 4.3e-16 59.7 7.5 4.9e-16 59.6 5.2 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2358 PF10184.4 ETO19436.1 - 0.03 14.2 0.1 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) CWC25 PF12542.3 ETO19437.1 - 0.059 13.8 1.8 0.1 13.0 1.2 1.4 1 0 0 1 1 1 0 Pre-mRNA splicing factor Cytochrom_C1 PF02167.10 ETO19438.1 - 2.8 7.5 8.1 0.067 12.8 0.5 1.9 2 1 0 2 2 2 0 Cytochrome C1 family ALMS_motif PF15309.1 ETO19439.1 - 0.047 13.5 0.6 0.047 13.5 0.4 3.3 3 1 1 4 4 4 0 ALMS motif Amino_oxidase PF01593.19 ETO19440.1 - 1.7e-17 63.6 3.4 4.9e-17 62.1 0.0 2.3 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 ETO19440.1 - 1.7e-12 47.1 0.1 3.4e-12 46.2 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SWIRM PF04433.12 ETO19440.1 - 2.9e-10 40.1 0.4 6.2e-10 39.0 0.3 1.6 1 0 0 1 1 1 1 SWIRM domain FAD_binding_2 PF00890.19 ETO19440.1 - 1.1e-06 27.8 0.6 1.9e-06 27.0 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETO19440.1 - 5.6e-06 25.5 0.0 1.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 ETO19440.1 - 4.8e-05 22.0 0.4 4.8e-05 22.0 0.2 1.7 2 0 0 2 2 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 ETO19440.1 - 7.8e-05 22.6 0.1 7.8e-05 22.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETO19440.1 - 9.5e-05 21.5 0.0 9.5e-05 21.5 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 ETO19440.1 - 0.00082 19.4 0.1 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 ETO19440.1 - 0.0018 17.4 0.2 0.0018 17.4 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 ETO19440.1 - 0.0026 18.1 0.3 0.0055 17.0 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 ETO19440.1 - 0.0074 15.8 0.3 0.0074 15.8 0.2 2.3 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 ETO19440.1 - 0.01 14.7 0.3 0.01 14.7 0.2 2.1 2 1 1 3 3 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 ETO19440.1 - 0.016 14.2 0.1 0.016 14.2 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase TrkA_N PF02254.13 ETO19440.1 - 0.017 15.0 0.1 0.032 14.2 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.14 ETO19440.1 - 0.073 12.2 0.1 0.17 10.9 0.1 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 ETO19440.1 - 0.14 11.0 0.1 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_10 PF13460.1 ETO19440.1 - 0.17 11.8 0.4 2.1 8.2 0.2 2.2 2 0 0 2 2 2 0 NADH(P)-binding NAD_binding_7 PF13241.1 ETO19440.1 - 0.17 12.1 1.0 0.31 11.3 0.0 1.9 2 0 0 2 2 1 0 Putative NAD(P)-binding CDC27 PF09507.5 ETO19440.1 - 0.85 8.7 37.3 1 8.4 25.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Paramyxo_ncap PF00973.14 ETO19441.1 - 0.034 12.8 0.6 0.043 12.5 0.4 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein MMPL PF03176.10 ETO19442.1 - 1.5e-22 79.7 1.4 2.5e-22 79.0 1.0 1.2 1 0 0 1 1 1 1 MMPL family Glyco_transf_49 PF13896.1 ETO19444.1 - 1.8e-15 56.8 0.7 2.8e-15 56.2 0.5 1.2 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 ETO19444.1 - 3.1e-06 26.4 0.1 4.1e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Tmemb_cc2 PF10267.4 ETO19446.1 - 1.3 7.4 41.4 1.2e+02 1.0 28.7 2.5 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein muHD PF10291.4 ETO19448.1 - 6.2e-07 28.8 0.0 7.5e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Adap_comp_sub PF00928.16 ETO19448.1 - 0.0073 15.4 0.4 0.011 14.7 0.3 1.3 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Snapin_Pallidin PF14712.1 ETO19449.1 - 0.12 12.6 1.3 0.18 12.0 0.9 1.3 1 0 0 1 1 1 0 Snapin/Pallidin IncA PF04156.9 ETO19449.1 - 0.14 11.6 3.1 0.17 11.4 2.2 1.2 1 0 0 1 1 1 0 IncA protein DIOX_N PF14226.1 ETO19450.1 - 2.4e-07 31.2 1.1 1.1e-06 29.1 0.8 1.9 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal EF-hand_1 PF00036.27 ETO19451.1 - 6.3e-05 21.9 0.5 0.00012 21.1 0.3 1.4 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 ETO19451.1 - 0.00026 20.5 0.4 0.00048 19.6 0.2 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 ETO19451.1 - 0.0042 17.2 0.1 0.0077 16.3 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_10 PF14788.1 ETO19451.1 - 0.018 14.6 0.7 0.047 13.3 0.5 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 ETO19451.1 - 0.032 14.1 0.2 0.086 12.7 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain Lectin_N PF03954.9 ETO19453.1 - 0.027 13.8 0.7 0.07 12.5 0.5 1.7 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF3287 PF11690.3 ETO19453.1 - 0.33 11.0 4.5 0.35 10.9 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) CCER1 PF15482.1 ETO19454.1 - 0.2 11.2 2.0 0.32 10.5 1.4 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 CAP_GLY PF01302.20 ETO19455.1 - 1.1e-26 92.2 6.0 1.8e-13 49.9 0.1 2.5 2 0 0 2 2 2 2 CAP-Gly domain dCMP_cyt_deam_1 PF00383.17 ETO19456.1 - 0.015 14.9 0.1 0.04 13.5 0.0 1.8 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region DNA_pol_B_thumb PF14791.1 ETO19457.1 - 9e-21 73.3 0.0 3e-20 71.6 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 ETO19457.1 - 1.5e-08 34.6 0.0 5.2e-08 32.9 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase beta palm Bro-N PF02498.12 ETO19457.1 - 0.1 12.9 0.1 0.51 10.6 0.0 2.1 2 0 0 2 2 2 0 BRO family, N-terminal domain DUF957 PF06117.6 ETO19458.1 - 0.025 14.1 0.9 0.35 10.4 0.0 2.8 3 0 0 3 3 3 0 Enterobacterial protein of unknown function (DUF957) FlgN PF05130.7 ETO19458.1 - 0.49 10.6 11.6 0.12 12.6 4.2 2.2 1 1 1 2 2 2 0 FlgN protein Peptidase_A21 PF03566.8 ETO19458.1 - 0.66 7.9 4.7 0.83 7.6 3.3 1.2 1 0 0 1 1 1 0 Peptidase family A21 DUF745 PF05335.8 ETO19458.1 - 0.74 9.2 5.2 0.25 10.8 0.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF745) UME PF08064.8 ETO19458.1 - 1.7 8.6 5.2 0.54 10.2 0.6 2.2 2 0 0 2 2 2 0 UME (NUC010) domain DUF2217 PF10265.4 ETO19458.1 - 3 6.4 10.4 4.4 5.9 7.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF445 PF04286.7 ETO19458.1 - 9.3 5.6 17.8 17 4.7 12.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) RGS PF00615.14 ETO19459.1 - 0.00013 21.9 1.0 0.00029 20.9 0.7 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain Apocytochr_F_C PF01333.14 ETO19459.1 - 0.094 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Apocytochrome F, C-terminal Snf7 PF03357.16 ETO19460.1 - 3.2e-06 26.6 22.1 6.1e-05 22.4 6.2 2.1 2 0 0 2 2 2 2 Snf7 DUF4437 PF14499.1 ETO19460.1 - 0.0017 17.3 0.3 0.0032 16.4 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4437) DUF29 PF01724.11 ETO19460.1 - 0.023 14.5 2.3 0.044 13.6 1.3 1.8 1 1 0 1 1 1 0 Domain of unknown function DUF29 Prefoldin_2 PF01920.15 ETO19460.1 - 0.025 14.3 3.3 0.025 14.3 2.3 3.1 3 1 0 3 3 3 0 Prefoldin subunit Phage_cap_E PF03864.10 ETO19460.1 - 0.039 12.8 0.1 0.066 12.1 0.0 1.3 1 0 0 1 1 1 0 Phage major capsid protein E SID-1_RNA_chan PF13965.1 ETO19460.1 - 0.084 11.0 9.2 0.0071 14.5 2.3 1.6 1 1 0 2 2 2 0 dsRNA-gated channel SID-1 ORF6C PF10552.4 ETO19460.1 - 0.98 9.1 7.6 0.11 12.1 1.5 2.1 2 0 0 2 2 2 0 ORF6C domain Mgr1 PF08602.5 ETO19460.1 - 3.5 6.5 8.5 0.21 10.5 2.3 1.5 2 0 0 2 2 2 0 Mgr1-like, i-AAA protease complex subunit SPOUT_MTase PF02590.12 ETO19460.1 - 4.2 7.0 7.8 0.34 10.6 1.8 1.8 2 0 0 2 2 2 0 Predicted SPOUT methyltransferase DUF2408 PF10303.4 ETO19460.1 - 7.7 6.6 11.7 1.2 9.1 3.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Glyco_transf_10 PF00852.14 ETO19462.1 - 7.8e-40 136.5 0.2 1.6e-39 135.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) IBR PF01485.16 ETO19463.1 - 6e-06 26.0 9.0 6e-06 26.0 6.2 5.4 4 2 1 5 5 5 3 IBR domain zf-C3HC4 PF00097.20 ETO19463.1 - 6.9e-05 22.4 6.0 6.9e-05 22.4 4.2 4.7 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) Afi1 PF07792.7 ETO19464.1 - 0.23 11.4 7.8 4.8 7.1 0.1 2.8 2 1 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Claudin_2 PF13903.1 ETO19464.1 - 0.28 10.8 1.5 0.62 9.7 1.0 1.5 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Iso_dh PF00180.15 ETO19465.1 - 1.4e-36 126.1 0.0 1.7e-36 125.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Iso_dh PF00180.15 ETO19466.1 - 5.1e-11 42.1 0.0 2.8e-10 39.6 0.0 1.8 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase WD40 PF00400.27 ETO19468.1 - 6.1e-09 35.4 0.3 1.4e-08 34.2 0.2 1.6 1 0 0 1 1 1 1 WD domain, G-beta repeat DUF1754 PF08555.5 ETO19468.1 - 0.011 16.2 11.8 0.13 12.8 1.1 2.9 3 0 0 3 3 3 0 Eukaryotic family of unknown function (DUF1754) DUF912 PF06024.7 ETO19468.1 - 0.035 14.1 5.8 2 8.4 0.0 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) MDFI PF15316.1 ETO19468.1 - 0.64 9.9 0.0 0.64 9.9 0.0 2.2 3 0 0 3 3 3 0 MyoD family inhibitor Mcp5_PH PF12814.2 ETO19469.1 - 0.0039 17.0 0.0 0.0076 16.1 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology CCP_MauG PF03150.9 ETO19469.1 - 0.059 13.6 0.0 0.096 12.9 0.0 1.5 1 1 0 1 1 1 0 Di-haem cytochrome c peroxidase TFIIH_BTF_p62_N PF08567.6 ETO19469.1 - 0.068 12.8 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain Viral_DNA_Zn_bi PF03728.8 ETO19470.1 - 0.041 13.9 0.3 0.072 13.1 0.1 1.5 1 1 0 1 1 1 0 Viral DNA-binding protein, zinc binding domain SSP160 PF06933.6 ETO19470.1 - 0.05 11.5 8.4 0.049 11.6 5.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 ETO19470.1 - 0.09 12.5 5.9 0.17 11.6 4.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF4634 PF15465.1 ETO19470.1 - 0.094 12.9 1.4 0.17 12.1 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4634) DUF966 PF06136.8 ETO19470.1 - 2 7.7 10.2 2.6 7.3 7.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Hamartin PF04388.7 ETO19470.1 - 3.4 6.2 9.5 3.9 6.0 6.6 1.0 1 0 0 1 1 1 0 Hamartin protein DUF4337 PF14235.1 ETO19472.1 - 3.2e-05 23.8 0.7 4.8e-05 23.2 0.2 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4337) YxiJ PF14176.1 ETO19472.1 - 0.0063 16.6 1.6 0.014 15.4 0.8 1.9 1 1 0 1 1 1 1 YxiJ-like protein DUF4239 PF14023.1 ETO19472.1 - 0.028 13.7 2.2 0.11 11.8 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF4239) DUF1411 PF07199.6 ETO19472.1 - 0.041 13.3 0.1 0.068 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) Peptidase_M3_N PF08439.5 ETO19472.1 - 0.062 13.3 0.4 0.19 11.8 0.3 1.8 1 0 0 1 1 1 0 Oligopeptidase F DUF4188 PF13826.1 ETO19472.1 - 0.091 12.8 0.7 0.21 11.7 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4188) ATG16 PF08614.6 ETO19472.1 - 0.2 11.4 9.5 1.5 8.5 0.8 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) CENP-Q PF13094.1 ETO19472.1 - 0.42 10.6 7.2 0.047 13.7 0.6 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Val_tRNA-synt_C PF10458.4 ETO19472.1 - 2 8.5 5.9 16 5.6 0.5 3.1 3 1 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm Sds3 PF08598.6 ETO19472.1 - 6.6 6.2 10.4 1 8.8 1.0 2.3 2 0 0 2 2 2 0 Sds3-like Utp14 PF04615.8 ETO19473.1 - 0.62 8.1 23.3 0.74 7.9 16.1 1.0 1 0 0 1 1 1 0 Utp14 protein DUF4228 PF14009.1 ETO19473.1 - 5.8 7.0 7.9 6.3 6.8 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) CENP-T PF15511.1 ETO19473.1 - 9.3 5.3 25.9 1.2 8.3 9.0 2.0 1 1 1 2 2 2 0 Centromere kinetochore component CENP-T RasGAP PF00616.14 ETO19474.1 - 3.2e-24 85.6 5.3 4.5e-24 85.1 3.7 1.1 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase eIF3_p135 PF12807.2 ETO19474.1 - 0.095 12.6 1.8 0.19 11.6 1.2 1.6 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 DUF1951 PF09188.5 ETO19474.1 - 0.59 10.0 4.7 0.38 10.6 1.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1951) Pkinase PF00069.20 ETO19475.1 - 5e-59 199.5 1.5 2.3e-34 118.7 0.5 2.1 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO19475.1 - 4.1e-25 88.3 0.8 1.6e-20 73.2 0.2 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 ETO19475.1 - 5.4e-05 22.3 0.4 0.00011 21.3 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETO19475.1 - 6.4e-05 22.0 0.2 0.05 12.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like 5_nucleotid PF05761.9 ETO19475.1 - 0.024 13.1 0.1 0.035 12.6 0.1 1.1 1 0 0 1 1 1 0 5' nucleotidase family APH PF01636.18 ETO19475.1 - 0.032 13.9 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family 6PGD PF00393.14 ETO19475.1 - 0.045 12.9 0.0 0.073 12.2 0.0 1.3 1 0 0 1 1 1 0 6-phosphogluconate dehydrogenase, C-terminal domain Corona_M PF01635.13 ETO19476.1 - 0.073 12.0 3.3 0.11 11.3 2.3 1.3 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein DHquinase_I PF01487.10 ETO19476.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Type I 3-dehydroquinase Alkyl_sulf_dimr PF14863.1 ETO19477.1 - 1.7e-25 89.9 0.2 2.5e-15 56.9 0.0 2.4 2 0 0 2 2 2 2 Alkyl sulfatase dimerisation Lactamase_B PF00753.22 ETO19477.1 - 5.9e-17 61.9 0.1 7.7e-12 45.2 0.1 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETO19477.1 - 6.3e-06 25.8 0.2 1.7e-05 24.4 0.1 1.8 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Alkyl_sulf_C PF14864.1 ETO19477.1 - 3.1e-05 23.9 0.2 0.00081 19.3 0.0 2.3 2 0 0 2 2 2 1 Alkyl sulfatase C-terminal Sulfate_transp PF00916.15 ETO19478.1 - 0.03 13.3 0.0 0.053 12.5 0.0 1.3 1 0 0 1 1 1 0 Sulfate transporter family Phage_GP20 PF06810.6 ETO19481.1 - 0.043 13.2 2.0 0.077 12.4 1.4 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 dCMP_cyt_deam_1 PF00383.17 ETO19483.1 - 6.1e-08 32.2 8.0 1.5e-07 31.0 5.6 1.7 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Med3 PF11593.3 ETO19483.1 - 2.3 7.3 11.9 3.7 6.6 8.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RasGEF PF00617.14 ETO19484.1 - 1.4e-21 77.1 1.2 1.4e-21 77.1 0.8 1.9 2 0 0 2 2 2 1 RasGEF domain DUF164 PF02591.10 ETO19484.1 - 0.057 13.2 0.3 0.057 13.2 0.2 2.1 3 0 0 3 3 3 0 Putative zinc ribbon domain Dicty_REP PF05086.7 ETO19485.1 - 6.2e-05 20.9 1.9 7.4e-05 20.7 1.3 1.0 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein PfkB PF00294.19 ETO19486.1 - 6.1e-08 32.1 0.0 8e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Nop14 PF04147.7 ETO19489.1 - 0.49 8.2 40.0 0.68 7.7 27.7 1.3 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 ETO19489.1 - 1.7 7.0 38.4 2 6.7 26.6 1.1 1 0 0 1 1 1 0 Daxx Family Hid1 PF12722.2 ETO19489.1 - 2.2 5.8 28.9 2.7 5.5 20.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CENP-T PF15511.1 ETO19489.1 - 4.4 6.4 21.2 6.6 5.8 14.7 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Pkinase PF00069.20 ETO19490.1 - 1.4e-21 76.7 0.0 2.4e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO19490.1 - 6.7e-10 38.4 0.0 1e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO19490.1 - 0.019 13.9 0.0 0.029 13.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like SMN PF06003.7 ETO19491.1 - 0.7 8.9 5.2 0.52 9.3 2.1 1.8 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) FMO-like PF00743.14 ETO19492.1 - 4.3e-14 51.6 0.1 5.3e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 ETO19492.1 - 1.7e-10 41.2 0.0 2.5e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETO19492.1 - 5.4e-08 32.7 0.0 7.9e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 ETO19492.1 - 0.0003 20.6 0.0 0.00049 19.9 0.0 1.5 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 ETO19492.1 - 0.001 19.4 0.0 0.0072 16.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETO19492.1 - 0.0029 16.5 0.0 0.0033 16.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 ETO19492.1 - 0.0033 16.5 0.0 0.0097 15.0 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 ETO19492.1 - 0.03 14.1 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 ETO19492.1 - 0.048 13.4 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 ThiF family HI0933_like PF03486.9 ETO19492.1 - 0.093 11.1 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein AcetylCoA_hyd_C PF13336.1 ETO19494.1 - 4.7e-62 208.2 0.0 1.6e-61 206.4 0.0 1.8 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.10 ETO19494.1 - 0.0002 21.1 0.1 0.21 11.3 0.0 2.3 2 0 0 2 2 2 2 Acetyl-CoA hydrolase/transferase N-terminal domain Metallophos PF00149.23 ETO19495.1 - 4.5e-05 22.9 0.2 5.5e-05 22.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 ETO19495.1 - 0.013 15.2 0.0 0.015 15.1 0.0 1.1 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain FTH PF01827.22 ETO19496.1 - 0.052 13.1 0.4 0.073 12.6 0.3 1.3 1 0 0 1 1 1 0 FTH domain Plasmod_MYXSPDY PF07981.6 ETO19497.1 - 1.1 9.0 4.1 2.4 7.9 2.8 1.5 1 0 0 1 1 1 0 Plasmodium repeat_MYXSPDY Claudin_2 PF13903.1 ETO19498.1 - 0.78 9.4 8.4 48 3.5 5.8 2.2 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Ank_2 PF12796.2 ETO19499.1 - 1.2e-23 83.1 0.5 6.9e-13 48.7 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETO19499.1 - 6e-23 79.4 1.3 4.8e-07 29.2 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 ETO19499.1 - 1.2e-20 73.4 0.6 4.2e-09 36.6 0.0 2.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO19499.1 - 3.5e-17 60.8 0.7 0.00044 20.2 0.0 4.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 ETO19499.1 - 4.3e-15 55.3 0.3 2.5e-07 30.7 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) COMPASS-Shg1 PF05205.7 ETO19499.1 - 0.0011 19.2 0.5 0.0011 19.2 0.3 1.6 2 1 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 Glyco_hydro_38 PF01074.17 ETO19503.1 - 3.8e-34 118.1 0.3 5.9e-34 117.5 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 ETO19503.1 - 1.7e-17 63.3 0.0 3.5e-17 62.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 ETO19503.1 - 9.1e-15 54.6 0.3 2.5e-14 53.2 0.2 1.8 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Asp_protease PF09668.5 ETO19505.1 - 3e-21 75.2 0.1 4.8e-21 74.5 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 ETO19505.1 - 1.3e-08 34.1 1.7 2.9e-08 32.9 0.1 2.3 3 0 0 3 3 3 1 Ubiquitin family gag-asp_proteas PF13975.1 ETO19505.1 - 0.00013 21.6 0.0 0.00029 20.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 ETO19505.1 - 0.00056 20.3 0.0 0.0016 18.8 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease Rad60-SLD PF11976.3 ETO19505.1 - 0.00059 19.4 0.8 0.002 17.7 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like FAM176 PF14851.1 ETO19506.1 - 0.11 12.1 1.8 0.2 11.3 1.2 1.4 1 0 0 1 1 1 0 FAM176 family Nucleoplasmin PF03066.10 ETO19506.1 - 0.19 11.2 5.2 0.31 10.5 3.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin RNase_H2_suC PF08615.6 ETO19506.1 - 1.1 9.1 4.6 2.8 7.7 3.2 1.5 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) PBP1_TM PF14812.1 ETO19506.1 - 1.4 9.3 13.2 0.41 10.9 5.4 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal KRAP_IP3R_bind PF14722.1 ETO19507.1 - 0.032 13.8 0.6 2.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain ALO PF04030.9 ETO19508.1 - 7.4e-16 58.5 0.2 2e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 ETO19508.1 - 5.2e-11 42.1 0.2 1.1e-10 41.1 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain ADH_zinc_N PF00107.21 ETO19509.1 - 6.1e-20 71.0 0.3 1.1e-19 70.2 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETO19509.1 - 7.8e-09 35.2 2.5 1.2e-08 34.7 1.4 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.14 ETO19509.1 - 0.049 12.7 0.0 0.061 12.4 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF521 PF04412.8 ETO19509.1 - 0.057 11.9 0.1 0.077 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF521) MIP-T3 PF10243.4 ETO19510.1 - 0.094 11.1 27.9 0.12 10.8 19.4 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Sin3_corepress PF08295.7 ETO19511.1 - 2.9e-18 65.4 0.4 8.4e-18 63.9 0.0 2.0 2 0 0 2 2 2 1 Sin3 family co-repressor S1 PF00575.18 ETO19512.1 - 3.5e-05 23.7 0.0 6.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Bromodomain PF00439.20 ETO19513.1 - 7.3e-08 32.2 0.0 1.7e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Bromodomain Daxx PF03344.10 ETO19513.1 - 0.0002 20.0 22.8 0.00026 19.6 15.8 1.1 1 0 0 1 1 1 1 Daxx Family VID27 PF08553.5 ETO19513.1 - 0.048 11.8 12.4 0.074 11.2 8.6 1.3 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF740 PF05340.7 ETO19513.1 - 0.25 9.6 10.1 0.35 9.1 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Trypan_PARP PF05887.6 ETO19513.1 - 0.28 10.9 17.1 0.52 10.1 11.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RNA_pol_Rpc4 PF05132.9 ETO19513.1 - 0.38 10.7 5.6 1 9.3 3.9 1.8 1 0 0 1 1 1 0 RNA polymerase III RPC4 Tom37_C PF11801.3 ETO19513.1 - 0.6 9.9 6.0 1.1 9.0 4.2 1.5 1 0 0 1 1 1 0 Tom37 C-terminal domain BSP_II PF05432.6 ETO19513.1 - 0.64 9.2 26.0 0.027 13.7 13.0 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) TRAP_alpha PF03896.11 ETO19513.1 - 0.77 8.6 11.6 1.5 7.7 8.0 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Prog_receptor PF02161.10 ETO19513.1 - 1.8 7.3 5.7 2.9 6.6 3.6 1.7 2 0 0 2 2 2 0 Progesterone receptor CobT PF06213.7 ETO19513.1 - 7 5.6 25.4 0.21 10.6 12.7 1.9 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT FAM176 PF14851.1 ETO19513.1 - 7.8 6.1 13.4 0.99 9.0 6.0 1.9 2 0 0 2 2 2 0 FAM176 family Pkinase_Tyr PF07714.12 ETO19514.1 - 1.8e-45 155.0 0.0 2.2e-45 154.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 ETO19514.1 - 3.2e-42 144.5 0.0 4.1e-42 144.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 ETO19514.1 - 0.076 11.9 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Kinase-like BSP_II PF05432.6 ETO19516.1 - 0.0041 16.4 3.1 0.0045 16.3 2.1 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Nucleoplasmin PF03066.10 ETO19516.1 - 0.027 13.9 2.4 0.028 13.9 1.6 1.2 1 0 0 1 1 1 0 Nucleoplasmin Myc_N PF01056.13 ETO19516.1 - 0.046 12.8 1.4 0.047 12.8 1.0 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Ribosomal_60s PF00428.14 ETO19516.1 - 4.7 7.6 9.5 6.9 7.1 6.6 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein 3Beta_HSD PF01073.14 ETO19517.1 - 1e-13 50.6 0.0 1.1e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 ETO19517.1 - 2.4e-13 50.4 0.0 3e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETO19517.1 - 9.9e-11 41.5 0.0 1.3e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 ETO19517.1 - 6.5e-10 38.6 0.0 8.3e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 ETO19517.1 - 1.5e-06 28.2 0.0 2.1e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETO19517.1 - 1.9e-05 24.4 0.0 2.5e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 ETO19517.1 - 0.0005 19.0 0.0 0.001 18.0 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 ETO19517.1 - 0.039 12.8 0.0 0.05 12.4 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 ETO19517.1 - 0.04 12.8 0.0 0.051 12.5 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase RmlD_sub_bind PF04321.12 ETO19517.1 - 0.062 12.1 0.0 0.083 11.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short_C2 PF13561.1 ETO19517.1 - 0.065 12.9 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DUF2193 PF09959.4 ETO19517.1 - 0.12 10.5 0.0 0.21 9.8 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2193) CAP_GLY PF01302.20 ETO19518.1 - 1.7e-10 40.4 0.3 3.5e-10 39.4 0.2 1.5 1 0 0 1 1 1 1 CAP-Gly domain Vhr1 PF04001.8 ETO19519.1 - 0.21 11.5 2.6 0.92 9.4 0.3 2.2 2 0 0 2 2 2 0 Transcription factor Vhr1 RGS PF00615.14 ETO19520.1 - 1.9e-06 27.9 0.2 4.4e-06 26.7 0.2 1.6 1 1 0 1 1 1 1 Regulator of G protein signaling domain NMD3 PF04981.8 ETO19521.1 - 2.7e-30 105.2 1.2 2.7e-30 105.2 0.8 1.6 2 0 0 2 2 2 1 NMD3 family Sec3-PIP2_bind PF15277.1 ETO19521.1 - 0.069 13.0 1.5 0.4 10.5 0.8 2.4 2 0 0 2 2 2 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH CENP-F_leu_zip PF10473.4 ETO19522.1 - 1.3e-06 28.2 49.2 0.00023 21.0 12.2 3.4 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rootletin PF15035.1 ETO19522.1 - 1.1e-05 25.5 17.4 1.1e-05 25.5 12.0 2.4 1 1 1 2 2 2 1 Ciliary rootlet component, centrosome cohesion GAS PF13851.1 ETO19522.1 - 4.3e-05 22.8 44.0 0.00069 18.8 11.7 3.3 1 1 3 4 4 4 3 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 ETO19522.1 - 6.8e-05 22.1 17.9 0.0013 17.9 5.1 2.1 1 1 1 2 2 2 2 Reovirus sigma C capsid protein IncA PF04156.9 ETO19522.1 - 7.4e-05 22.4 49.0 0.00011 21.8 18.6 3.2 1 1 1 2 2 2 2 IncA protein MAD PF05557.8 ETO19522.1 - 0.0001 20.6 50.0 0.00021 19.5 34.6 1.5 1 1 0 1 1 1 1 Mitotic checkpoint protein SlyX PF04102.7 ETO19522.1 - 0.00014 22.1 35.5 0.0046 17.3 3.2 4.7 1 1 4 5 5 5 2 SlyX DUF869 PF05911.6 ETO19522.1 - 0.00018 19.8 40.8 0.00037 18.9 13.1 2.6 1 1 2 3 3 3 2 Plant protein of unknown function (DUF869) Cast PF10174.4 ETO19522.1 - 0.00046 18.3 43.1 0.00063 17.9 29.9 1.2 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone DUF1192 PF06698.6 ETO19522.1 - 0.00061 19.5 7.5 0.0017 18.1 0.9 3.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) CENP-Q PF13094.1 ETO19522.1 - 0.00091 19.2 50.2 0.0027 17.7 13.5 3.6 1 1 3 4 4 4 1 CENP-Q, a CENPA-CAD centromere complex subunit Spc24 PF08286.6 ETO19522.1 - 0.0011 18.7 38.2 0.056 13.1 1.6 4.4 1 1 3 4 4 4 2 Spc24 subunit of Ndc80 DUF2968 PF11180.3 ETO19522.1 - 0.0012 18.2 37.4 0.033 13.5 8.2 3.2 1 1 2 3 3 3 2 Protein of unknown function (DUF2968) DUF3450 PF11932.3 ETO19522.1 - 0.0015 17.8 34.7 0.0096 15.2 6.2 3.6 1 1 2 3 3 3 1 Protein of unknown function (DUF3450) Atg14 PF10186.4 ETO19522.1 - 0.0017 17.3 42.8 0.0095 14.9 9.8 2.9 1 1 1 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 Lebercilin PF15619.1 ETO19522.1 - 0.0018 17.7 38.1 0.0018 17.7 26.4 2.5 1 1 2 3 3 3 1 Ciliary protein causing Leber congenital amaurosis disease Baculo_PEP_C PF04513.7 ETO19522.1 - 0.0019 18.0 15.8 0.11 12.3 2.2 2.5 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4200 PF13863.1 ETO19522.1 - 0.0022 17.9 42.8 0.044 13.7 9.8 3.2 1 1 2 3 3 3 2 Domain of unknown function (DUF4200) Filament PF00038.16 ETO19522.1 - 0.0023 17.4 37.4 0.18 11.2 9.4 2.5 1 1 0 1 1 1 1 Intermediate filament protein HrpB7 PF09486.5 ETO19522.1 - 0.0035 17.2 23.8 0.023 14.6 7.0 3.2 1 1 2 3 3 3 2 Bacterial type III secretion protein (HrpB7) PspA_IM30 PF04012.7 ETO19522.1 - 0.0036 16.6 43.0 0.062 12.6 12.8 3.7 1 1 3 4 4 4 2 PspA/IM30 family Myosin_tail_1 PF01576.14 ETO19522.1 - 0.0039 15.0 44.0 0.13 10.0 15.9 1.7 1 1 0 1 1 1 1 Myosin tail DUF4201 PF13870.1 ETO19522.1 - 0.004 16.6 39.4 0.0059 16.0 10.0 3.0 1 1 0 2 2 2 1 Domain of unknown function (DUF4201) Nup54 PF13874.1 ETO19522.1 - 0.0049 16.5 12.0 0.0049 16.5 8.3 3.4 1 1 2 4 4 3 2 Nucleoporin complex subunit 54 DUF641 PF04859.7 ETO19522.1 - 0.0052 16.5 30.8 0.52 10.0 2.3 3.8 1 1 4 5 5 5 3 Plant protein of unknown function (DUF641) FlaC_arch PF05377.6 ETO19522.1 - 0.0056 16.5 26.1 0.095 12.6 1.4 5.3 3 2 2 5 5 5 2 Flagella accessory protein C (FlaC) Bacillus_HBL PF05791.6 ETO19522.1 - 0.0057 16.0 4.5 0.0057 16.0 3.1 3.9 1 1 3 4 4 4 1 Bacillus haemolytic enterotoxin (HBL) Mod_r PF07200.8 ETO19522.1 - 0.0095 15.8 16.3 0.0095 15.8 11.3 3.5 1 1 2 3 3 3 1 Modifier of rudimentary (Mod(r)) protein Syntaxin PF00804.20 ETO19522.1 - 0.0097 16.0 6.5 0.0097 16.0 4.5 3.6 1 1 2 3 3 3 2 Syntaxin ADIP PF11559.3 ETO19522.1 - 0.014 15.3 47.4 0.4 10.5 12.1 3.7 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.6 ETO19522.1 - 0.016 13.9 38.9 0.095 11.3 9.8 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein Prefoldin_2 PF01920.15 ETO19522.1 - 0.017 14.8 42.8 1.1 9.0 3.0 5.5 1 1 3 5 5 5 0 Prefoldin subunit WEMBL PF05701.6 ETO19522.1 - 0.018 13.5 42.8 0.025 13.0 29.7 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Mnd1 PF03962.10 ETO19522.1 - 0.019 14.6 40.9 0.38 10.3 12.8 3.5 1 1 3 4 4 4 0 Mnd1 family Tropomyosin_1 PF12718.2 ETO19522.1 - 0.022 14.6 49.2 0.17 11.7 17.7 4.1 1 1 3 4 4 4 0 Tropomyosin like NPV_P10 PF05531.7 ETO19522.1 - 0.031 14.5 18.0 0.25 11.6 1.4 4.0 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DivIVA PF05103.8 ETO19522.1 - 0.05 13.6 38.9 0.085 12.9 9.9 4.0 1 1 2 4 4 3 0 DivIVA protein FliJ PF02050.11 ETO19522.1 - 0.056 13.4 38.2 0.49 10.4 7.4 3.0 1 1 1 3 3 3 0 Flagellar FliJ protein Fib_alpha PF08702.5 ETO19522.1 - 0.063 13.3 29.8 0.71 9.9 8.1 3.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family APG6 PF04111.7 ETO19522.1 - 0.075 12.0 45.9 0.81 8.6 12.4 2.9 1 1 2 3 3 3 0 Autophagy protein Apg6 ATG16 PF08614.6 ETO19522.1 - 0.081 12.7 48.3 0.54 10.0 21.2 3.8 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Med9 PF07544.8 ETO19522.1 - 0.093 12.4 30.8 0.95 9.2 7.2 4.8 1 1 3 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Prefoldin PF02996.12 ETO19522.1 - 0.13 11.8 33.3 0.29 10.8 1.1 5.2 2 1 3 5 5 5 0 Prefoldin subunit DUF4164 PF13747.1 ETO19522.1 - 0.14 12.2 31.5 0.37 10.9 5.6 3.9 2 2 1 3 3 3 0 Domain of unknown function (DUF4164) Tropomyosin PF00261.15 ETO19522.1 - 0.15 11.1 39.2 0.39 9.7 10.9 2.4 1 1 0 1 1 1 0 Tropomyosin DUF972 PF06156.8 ETO19522.1 - 0.16 12.3 37.7 1.3 9.3 1.7 4.7 1 1 4 5 5 5 0 Protein of unknown function (DUF972) AAA_13 PF13166.1 ETO19522.1 - 0.17 10.3 32.5 0.094 11.1 20.6 1.7 1 1 1 2 2 2 0 AAA domain DUF342 PF03961.8 ETO19522.1 - 0.2 10.0 34.6 0.37 9.1 9.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF342) MscS_porin PF12795.2 ETO19522.1 - 0.21 10.8 41.6 3.1 7.0 3.6 3.1 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Borrelia_REV PF03978.8 ETO19522.1 - 0.21 11.3 14.4 0.014 15.1 4.7 2.3 1 1 1 2 2 2 0 Borrelia burgdorferi REV protein DUF4140 PF13600.1 ETO19522.1 - 0.22 11.9 28.1 0.055 13.9 1.7 4.2 1 1 3 4 4 4 0 N-terminal domain of unknown function (DUF4140) BLOC1_2 PF10046.4 ETO19522.1 - 0.27 11.3 29.7 1.8 8.7 4.5 4.2 1 1 4 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Dam1 PF08653.5 ETO19522.1 - 0.28 10.9 10.3 0.28 10.9 0.1 4.4 2 2 4 6 6 6 0 DASH complex subunit Dam1 DUF3584 PF12128.3 ETO19522.1 - 0.32 8.2 38.3 0.83 6.8 26.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) CCDC155 PF14662.1 ETO19522.1 - 0.32 10.5 48.2 0.12 11.9 21.4 3.0 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 Laminin_II PF06009.7 ETO19522.1 - 0.37 10.5 30.2 0.22 11.2 6.3 3.2 1 1 2 3 3 3 0 Laminin Domain II DUF848 PF05852.6 ETO19522.1 - 0.37 10.6 35.4 1.7 8.4 8.8 3.9 1 1 3 4 4 4 0 Gammaherpesvirus protein of unknown function (DUF848) TBPIP PF07106.8 ETO19522.1 - 0.51 9.8 40.9 1 8.8 10.8 4.1 1 1 3 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) MbeD_MobD PF04899.7 ETO19522.1 - 0.53 10.2 27.8 0.11 12.4 2.8 4.3 2 1 2 4 4 4 0 MbeD/MobD like DUF1664 PF07889.7 ETO19522.1 - 0.67 9.7 23.3 2.1 8.1 2.3 3.9 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) CALCOCO1 PF07888.6 ETO19522.1 - 0.68 8.1 41.4 1.2 7.2 10.1 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like THOC7 PF05615.8 ETO19522.1 - 0.86 9.8 37.1 25 5.1 12.2 3.6 1 1 1 2 2 2 0 Tho complex subunit 7 CASP_C PF08172.7 ETO19522.1 - 1 8.3 27.4 0.37 9.7 15.6 2.6 1 1 0 1 1 1 0 CASP C terminal LIF_OSM PF01291.12 ETO19522.1 - 1.3 8.9 14.0 1.5 8.7 2.4 3.2 1 1 1 2 2 2 0 LIF / OSM family DUF812 PF05667.6 ETO19522.1 - 1.3 7.4 38.0 1.4 7.3 4.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF812) TMCO5 PF14992.1 ETO19522.1 - 1.3 8.0 39.7 0.21 10.7 12.0 2.3 1 1 1 2 2 2 0 TMCO5 family HOOK PF05622.7 ETO19522.1 - 1.6 6.4 41.4 21 2.7 28.6 2.2 1 1 0 1 1 1 0 HOOK protein Syntaxin-6_N PF09177.6 ETO19522.1 - 1.9 8.9 29.0 0.09 13.1 5.7 3.9 1 1 2 3 3 3 0 Syntaxin 6, N-terminal EzrA PF06160.7 ETO19522.1 - 1.9 6.5 32.8 1.8 6.6 8.7 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Tup_N PF08581.5 ETO19522.1 - 2 8.6 30.4 0.29 11.3 2.6 3.8 1 1 2 3 3 3 0 Tup N-terminal HlyD PF00529.15 ETO19522.1 - 2.2 7.4 29.8 1.6 7.9 4.6 2.6 1 1 2 3 3 3 0 HlyD family secretion protein GldM_C PF12080.3 ETO19522.1 - 2.7 7.8 4.8 1.2 9.0 1.5 1.8 2 0 0 2 2 1 0 GldM C-terminal domain FliD_N PF02465.13 ETO19522.1 - 2.8 8.3 28.4 1.8 8.9 3.9 4.0 1 1 3 4 4 4 0 Flagellar hook-associated protein 2 N-terminus Fez1 PF06818.10 ETO19522.1 - 3.1 7.7 38.6 0.064 13.2 17.1 2.3 1 1 1 2 2 2 0 Fez1 bZIP_1 PF00170.16 ETO19522.1 - 3.4 7.6 46.4 0.83 9.6 5.1 6.7 2 1 5 7 7 7 0 bZIP transcription factor PEARLI-4 PF05278.7 ETO19522.1 - 3.5 6.9 31.7 0.24 10.7 4.1 3.3 1 1 2 3 3 3 0 Arabidopsis phospholipase-like protein (PEARLI 4) TMF_TATA_bd PF12325.3 ETO19522.1 - 3.6 7.3 43.5 2.1 8.1 9.8 4.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.7 ETO19522.1 - 3.9 7.2 49.3 3.1 7.5 9.1 3.2 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein ABC_tran_2 PF12848.2 ETO19522.1 - 4 7.3 30.7 0.079 12.8 3.1 4.1 1 1 2 4 4 4 0 ABC transporter DUF2353 PF09789.4 ETO19522.1 - 4.7 6.3 38.8 18 4.4 11.5 3.0 1 1 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) DivIC PF04977.10 ETO19522.1 - 4.8 6.7 37.2 0.12 11.8 1.9 5.7 1 1 4 6 6 6 0 Septum formation initiator DUF745 PF05335.8 ETO19522.1 - 5 6.6 30.8 12 5.3 9.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Ax_dynein_light PF10211.4 ETO19522.1 - 5 6.9 39.8 0.84 9.4 4.6 4.2 1 1 4 5 5 5 0 Axonemal dynein light chain ERM PF00769.14 ETO19522.1 - 5.3 6.5 48.4 3.7 7.0 15.3 3.1 1 1 2 3 3 3 0 Ezrin/radixin/moesin family Phage_lysis PF03245.8 ETO19522.1 - 6.6 6.7 22.4 2.5 8.0 6.7 3.0 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein Spc42p PF11544.3 ETO19522.1 - 8.2 6.4 28.9 0.24 11.3 1.6 5.2 1 1 4 5 5 4 0 Spindle pole body component Spc42p COG2 PF06148.6 ETO19522.1 - 8.3 6.2 26.2 5 7.0 3.2 3.8 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 bZIP_Maf PF03131.12 ETO19522.1 - 9.9 6.5 33.9 6.8 7.0 1.6 4.7 1 1 3 4 4 4 0 bZIP Maf transcription factor UPF0061 PF02696.9 ETO19523.1 - 3.9e-46 157.3 0.0 5.1e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Adaptin_N PF01602.15 ETO19525.1 - 1.5e-59 201.6 3.6 1.9e-59 201.3 2.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COG7 PF10191.4 ETO19525.1 - 0.0051 14.7 0.2 0.0082 14.1 0.1 1.3 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) Toxin_63 PF15541.1 ETO19525.1 - 0.036 14.0 0.0 15 5.6 0.0 2.7 2 0 0 2 2 2 0 Putative toxin 63 Zip PF02535.17 ETO19525.1 - 0.06 12.3 0.5 0.094 11.6 0.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CobT PF06213.7 ETO19525.1 - 0.087 11.9 13.2 0.16 11.1 9.1 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BSMAP PF12280.3 ETO19525.1 - 0.098 12.5 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Brain specific membrane anchored protein BUD22 PF09073.5 ETO19525.1 - 0.11 11.5 24.6 0.15 11.0 17.1 1.1 1 0 0 1 1 1 0 BUD22 Nucleo_P87 PF07267.6 ETO19525.1 - 0.14 10.7 8.8 0.21 10.2 6.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.9 ETO19525.1 - 0.38 8.7 16.1 0.5 8.3 11.2 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.7 ETO19525.1 - 0.95 9.3 12.8 1.4 8.7 8.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ycf1 PF05758.7 ETO19525.1 - 1.1 6.8 6.3 1.6 6.3 4.4 1.2 1 0 0 1 1 1 0 Ycf1 Tim54 PF11711.3 ETO19525.1 - 1.3 7.5 9.3 2 6.9 6.4 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Nop14 PF04147.7 ETO19525.1 - 1.6 6.5 24.2 2.5 5.9 16.8 1.2 1 0 0 1 1 1 0 Nop14-like family DUF2201_N PF13203.1 ETO19525.1 - 1.9 7.5 8.3 2.8 7.0 5.8 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain NPR3 PF03666.8 ETO19525.1 - 3.3 6.1 12.6 5.3 5.4 8.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 GAGA_bind PF06217.7 ETO19525.1 - 5.4 6.8 11.8 8.5 6.2 8.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF912 PF06024.7 ETO19525.1 - 8 6.5 12.1 7.1 6.7 5.9 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Hid1 PF12722.2 ETO19525.1 - 9.4 3.7 10.6 13 3.2 7.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PA28_beta PF02252.13 ETO19527.1 - 0.28 10.6 7.8 0.18 11.2 1.1 2.7 1 1 1 2 2 2 0 Proteasome activator pa28 beta subunit Mto2_bdg PF12808.2 ETO19527.1 - 1.2 9.2 7.7 2.5 8.2 1.4 2.6 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Rep_fac_C PF08542.6 ETO19527.1 - 3.7 7.5 9.2 4.4 7.3 4.1 2.4 1 1 1 2 2 2 0 Replication factor C C-terminal domain EF-hand_like PF09279.6 ETO19527.1 - 4.4 7.3 10.4 1.2 9.1 3.5 2.4 1 1 1 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like DUF2731 PF10806.3 ETO19528.1 - 1.1 9.5 6.1 1.4 9.2 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2731) RP-C_C PF11800.3 ETO19528.1 - 9.4 5.8 9.8 51 3.4 5.8 2.1 1 1 1 2 2 2 0 Replication protein C C-terminal region Imm22 PF15592.1 ETO19529.1 - 0.0038 17.5 0.4 0.0092 16.2 0.1 1.8 2 0 0 2 2 2 1 Immunity protein 22 RIC1 PF07064.8 ETO19529.1 - 0.011 15.1 0.6 0.019 14.4 0.4 1.3 1 0 0 1 1 1 0 RIC1 FtsH_ext PF06480.10 ETO19529.1 - 0.013 15.6 0.4 0.013 15.6 0.3 1.7 2 0 0 2 2 2 0 FtsH Extracellular Methyltransf_5 PF01795.14 ETO19529.1 - 0.041 13.1 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family DUF1426 PF07234.6 ETO19529.1 - 0.28 10.9 2.0 0.65 9.7 1.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1426) Aldo_ket_red PF00248.16 ETO19530.1 - 1.7e-54 184.5 0.3 2e-54 184.3 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3791 PF12668.2 ETO19530.1 - 0.0088 15.6 1.6 5.9 6.5 0.1 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3791) RGS PF00615.14 ETO19531.1 - 4.4e-06 26.7 1.8 2.4e-05 24.4 0.1 2.3 2 0 0 2 2 2 1 Regulator of G protein signaling domain DUF3849 PF12960.2 ETO19531.1 - 0.043 13.7 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3849) PhaG_MnhG_YufB PF03334.9 ETO19532.1 - 4.4 7.4 7.4 2 8.5 2.5 2.3 2 1 0 2 2 2 0 Na+/H+ antiporter subunit DUF4184 PF13803.1 ETO19533.1 - 0.014 14.7 0.1 0.021 14.1 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4184) CitMHS PF03600.11 ETO19534.1 - 0.033 12.7 8.1 0.037 12.6 5.6 1.1 1 0 0 1 1 1 0 Citrate transporter YMF19 PF02326.10 ETO19534.1 - 3.1 8.4 13.5 0.14 12.7 2.3 2.9 3 0 0 3 3 3 0 Plant ATP synthase F0 Frataxin_Cyay PF01491.11 ETO19535.1 - 0.043 13.6 0.6 0.11 12.3 0.2 1.8 2 0 0 2 2 2 0 Frataxin-like domain UQ_con PF00179.21 ETO19536.1 - 1.9e-07 30.5 0.0 3.9e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme NYN PF01936.13 ETO19537.1 - 2.3e-06 27.9 0.0 3e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 NYN domain U-box PF04564.10 ETO19539.1 - 0.00031 20.6 0.0 0.00076 19.3 0.0 1.7 1 0 0 1 1 1 1 U-box domain Rtf2 PF04641.7 ETO19539.1 - 0.015 14.4 0.5 0.015 14.4 0.3 3.4 3 1 0 3 3 3 0 Rtf2 RING-finger BLVR PF06375.6 ETO19539.1 - 0.53 10.0 29.0 0.022 14.5 4.5 3.5 3 1 0 3 3 3 0 Bovine leukaemia virus receptor (BLVR) Pkinase PF00069.20 ETO19542.1 - 7.3e-17 61.3 0.0 8.9e-17 61.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO19542.1 - 0.0026 16.8 0.2 0.0057 15.7 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 ETO19542.1 - 0.0032 16.3 0.5 0.0043 15.9 0.1 1.3 1 1 0 1 1 1 1 Poxvirus serine/threonine protein kinase HDNR PF15115.1 ETO19542.1 - 0.066 13.1 0.1 0.074 12.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function with conserved HDNR motif PQ-loop PF04193.9 ETO19543.1 - 3.5e-17 61.6 3.9 7.4e-17 60.6 2.7 1.6 1 0 0 1 1 1 1 PQ loop repeat DUF3278 PF11683.3 ETO19543.1 - 0.76 9.7 4.2 2 8.4 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) SelP_N PF04592.9 ETO19544.1 - 9.8e-05 21.8 4.2 0.00017 21.0 2.9 1.3 1 0 0 1 1 1 1 Selenoprotein P, N terminal region Pex14_N PF04695.8 ETO19544.1 - 0.00018 21.5 4.8 0.00082 19.4 2.0 2.3 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Spore_coat_CotO PF14153.1 ETO19544.1 - 0.00023 20.6 2.0 0.00029 20.3 1.4 1.1 1 0 0 1 1 1 1 Spore coat protein CotO Neur_chan_memb PF02932.11 ETO19544.1 - 0.0023 17.8 0.2 0.0033 17.3 0.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2370 PF10176.4 ETO19544.1 - 0.0092 15.3 0.4 0.015 14.6 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) FimP PF09766.4 ETO19544.1 - 0.012 14.7 6.5 0.016 14.3 4.5 1.1 1 0 0 1 1 1 0 Fms-interacting protein DUF2946 PF11162.3 ETO19544.1 - 0.017 15.3 0.0 0.055 13.6 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) Zip PF02535.17 ETO19544.1 - 0.049 12.6 13.5 0.05 12.5 5.6 2.2 1 1 1 2 2 2 0 ZIP Zinc transporter Suf PF05843.9 ETO19544.1 - 0.16 11.6 5.0 0.22 11.2 3.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF1183 PF06682.7 ETO19544.1 - 0.17 11.4 3.7 0.25 10.9 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) CDC45 PF02724.9 ETO19544.1 - 0.35 8.8 7.0 0.47 8.4 4.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SprA-related PF12118.3 ETO19544.1 - 0.59 9.4 19.1 0.78 9.0 13.2 1.1 1 0 0 1 1 1 0 SprA-related family RP-C_C PF11800.3 ETO19544.1 - 0.76 9.4 7.4 1.1 8.9 5.1 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF4207 PF13904.1 ETO19544.1 - 0.8 9.0 14.9 1.1 8.5 10.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) DUF1754 PF08555.5 ETO19544.1 - 1.3 9.7 8.5 1.9 9.1 5.9 1.2 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Senescence_reg PF04520.8 ETO19544.1 - 2.1 8.8 7.6 3.2 8.2 5.3 1.2 1 0 0 1 1 1 0 Senescence regulator BAF1_ABF1 PF04684.8 ETO19544.1 - 4.7 5.9 23.3 6.3 5.5 16.2 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Macoilin PF09726.4 ETO19544.1 - 5.4 5.1 12.5 7.8 4.6 8.7 1.2 1 0 0 1 1 1 0 Transmembrane protein HA2 PF04408.18 ETO19544.1 - 6 6.9 6.0 6 6.9 2.6 2.2 2 1 0 2 2 2 0 Helicase associated domain (HA2) RIC3 PF15361.1 ETO19544.1 - 6.4 6.9 8.2 10 6.3 5.7 1.3 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Med3 PF11593.3 ETO19544.1 - 9.4 5.3 19.1 13 4.8 13.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Zip PF02535.17 ETO19546.1 - 0.033 13.1 0.0 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_U40 PF10464.4 ETO19546.1 - 0.088 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase U40 OAD_gamma PF04277.8 ETO19546.1 - 0.16 12.3 0.3 1.1 9.7 0.0 2.1 1 1 1 2 2 2 0 Oxaloacetate decarboxylase, gamma chain PIG-P PF08510.7 ETO19546.1 - 0.18 11.4 1.2 0.46 10.1 0.0 2.0 1 1 1 2 2 2 0 PIG-P Arf PF00025.16 ETO19547.1 - 8.1e-30 103.3 0.0 8.7e-30 103.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 ETO19547.1 - 7.2e-08 31.5 0.4 1.2e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 G-protein alpha subunit Ras PF00071.17 ETO19547.1 - 3.3e-07 29.8 0.0 3.6e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO19547.1 - 5.2e-05 23.7 0.0 7.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 ETO19547.1 - 5.6e-05 22.6 0.0 6.1e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 ETO19547.1 - 0.006 15.7 0.0 0.0072 15.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region F-box-like PF12937.2 ETO19548.1 - 0.013 15.1 1.3 0.028 14.1 0.4 1.9 2 1 0 2 2 2 0 F-box-like ACDC PF14733.1 ETO19548.1 - 0.09 12.9 1.7 0.17 12.0 1.2 1.5 1 0 0 1 1 1 0 AP2-coincident C-terminal Glutaredoxin2_C PF04399.8 ETO19548.1 - 0.14 11.7 2.7 0.33 10.5 1.8 1.7 1 1 0 1 1 1 0 Glutaredoxin 2, C terminal domain CD36 PF01130.16 ETO19551.1 - 1.3e-07 30.3 0.1 7.8e-06 24.4 0.1 2.0 2 0 0 2 2 2 2 CD36 family SecY PF00344.15 ETO19552.1 - 0.0036 16.2 0.1 0.0045 15.9 0.1 1.2 1 0 0 1 1 1 1 SecY translocase DUF3810 PF12725.2 ETO19552.1 - 0.0056 15.6 1.8 0.007 15.3 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3810) Adeno_E3_14_5 PF04834.7 ETO19552.1 - 0.055 13.8 0.1 0.084 13.3 0.1 1.4 1 0 0 1 1 1 0 Early E3 14.5 kDa protein DUF4604 PF15377.1 ETO19552.1 - 0.57 10.3 10.8 0.9 9.7 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) OmpH PF03938.9 ETO19553.1 - 0.018 14.9 1.8 0.018 14.9 1.2 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Imm42 PF15601.1 ETO19553.1 - 0.37 10.2 3.5 0.57 9.5 0.4 2.4 1 1 2 3 3 3 0 Immunity protein 42 CaATP_NAI PF12515.3 ETO19553.1 - 0.46 10.0 2.0 0.49 9.9 0.1 1.9 2 0 0 2 2 2 0 Ca2+-ATPase N terminal autoinhibitory domain Tnp_P_element PF12017.3 ETO19553.1 - 1.9 7.6 8.5 0.28 10.3 3.1 1.6 2 0 0 2 2 2 0 Transposase protein NYD-SP28 PF14772.1 ETO19553.1 - 2.4 8.3 15.5 0.28 11.2 1.2 2.6 2 0 0 2 2 2 0 Sperm tail CopC PF04234.7 ETO19554.1 - 0.01 16.4 3.6 0.032 14.8 0.0 2.4 2 0 0 2 2 2 0 CopC domain SpoIIP PF07454.6 ETO19554.1 - 0.092 11.9 10.8 0.13 11.3 7.5 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Dynamin_N PF00350.18 ETO19554.1 - 0.23 11.2 5.8 0.27 11.0 2.9 1.8 2 0 0 2 2 2 0 Dynamin family DUF4557 PF15101.1 ETO19554.1 - 0.28 11.0 24.4 0.43 10.3 16.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) SpoIIIAH PF12685.2 ETO19554.1 - 0.35 10.3 17.8 5.5 6.4 0.0 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein Jiraiya PF15038.1 ETO19554.1 - 0.38 10.1 0.0 0.38 10.1 0.0 2.1 2 0 0 2 2 2 0 Jiraiya Pex14_N PF04695.8 ETO19554.1 - 0.44 10.5 18.8 0.76 9.8 13.1 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Dehalogenase PF13486.1 ETO19554.1 - 4.1 6.7 12.7 7 6.0 8.8 1.4 1 0 0 1 1 1 0 Reductive dehalogenase subunit DDRGK PF09756.4 ETO19554.1 - 4.4 6.6 25.1 6.9 6.0 17.4 1.3 1 0 0 1 1 1 0 DDRGK domain RNA_pol_Rpb1_5 PF04998.12 ETO19554.1 - 7.5 5.7 10.4 13 4.9 7.2 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 PTR2 PF00854.16 ETO19555.1 - 4.3e-18 65.2 0.4 4.3e-18 65.2 0.2 1.4 2 0 0 2 2 2 1 POT family UNC-50 PF05216.8 ETO19555.1 - 0.0068 15.6 3.9 0.0098 15.1 2.7 1.1 1 0 0 1 1 1 1 UNC-50 family DUF1440 PF07274.7 ETO19555.1 - 0.066 13.2 0.6 2.5 8.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1440) Cation_ATPase_C PF00689.16 ETO19555.1 - 0.067 12.7 0.2 0.094 12.2 0.2 1.2 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF373 PF04123.8 ETO19555.1 - 0.074 12.0 0.8 0.091 11.7 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) UPF0014 PF03649.8 ETO19555.1 - 0.091 11.9 0.4 0.15 11.1 0.3 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0014) Cytochrom_C_asm PF01578.15 ETO19555.1 - 0.52 9.8 4.1 0.6 9.6 1.2 1.9 1 1 1 2 2 2 0 Cytochrome C assembly protein His_Phos_1 PF00300.17 ETO19556.1 - 0.0099 15.9 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Suc_Fer-like PF06999.7 ETO19556.1 - 0.076 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Sucrase/ferredoxin-like DUF1749 PF08538.5 ETO19556.1 - 0.14 11.0 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Glyco_hyd_65N_2 PF14498.1 ETO19558.1 - 0.059 13.0 0.1 0.069 12.8 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DUF2615 PF11027.3 ETO19560.1 - 0.058 13.3 0.3 1 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) DUF912 PF06024.7 ETO19560.1 - 0.71 9.9 5.2 8.1 6.5 1.7 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) COX16 PF14138.1 ETO19560.1 - 2.9 8.1 7.9 0.55 10.4 3.1 1.6 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 TPR_11 PF13414.1 ETO19561.1 - 0.082 12.5 0.8 0.24 11.0 0.5 1.8 1 1 0 1 1 1 0 TPR repeat CDV3 PF15359.1 ETO19561.1 - 0.13 12.3 0.2 0.13 12.3 0.1 1.7 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 TPR_11 PF13414.1 ETO19562.1 - 4.3e-14 51.9 8.9 6.4e-11 41.7 0.8 3.3 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 ETO19562.1 - 3.8e-12 45.2 8.5 3.1e-05 23.3 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO19562.1 - 7e-12 44.5 0.6 4.8e-05 23.2 0.2 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO19562.1 - 1.6e-11 43.1 11.8 0.00082 19.1 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 ETO19562.1 - 3.5e-10 39.6 11.5 1.4e-06 28.1 0.4 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO19562.1 - 1.2e-07 31.9 4.4 3.5e-05 24.0 0.4 3.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO19562.1 - 3e-07 29.7 11.2 0.0017 17.9 0.0 4.3 4 1 1 5 5 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO19562.1 - 8.7e-07 29.4 3.8 0.00011 22.7 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO19562.1 - 2.4e-05 24.5 3.3 0.6 10.9 0.1 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 ETO19562.1 - 0.0015 18.6 0.1 0.96 9.6 0.0 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO19562.1 - 0.0027 17.8 4.1 0.0027 17.8 2.8 3.7 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 ETO19562.1 - 0.28 11.0 2.5 0.22 11.4 0.3 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO19562.1 - 4.1 8.0 6.0 3 8.5 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.27 ETO19563.1 - 9.9e-58 190.0 26.7 8.3e-12 44.5 0.1 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO19563.1 - 1.1e-09 37.0 2.6 0.13 10.3 0.1 4.9 2 1 2 5 5 5 4 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO19563.1 - 4.2e-07 30.2 1.7 2.1e-06 28.0 1.2 2.3 1 0 0 1 1 1 1 TRAF-type zinc finger IncA PF04156.9 ETO19563.1 - 0.011 15.3 17.3 0.023 14.2 12.0 1.5 1 0 0 1 1 1 0 IncA protein WD40 PF00400.27 ETO19564.1 - 2.2e-71 233.3 7.3 4.2e-13 48.6 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO19564.1 - 2.8e-11 43.4 0.3 0.00032 20.4 0.1 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO19564.1 - 8.2e-08 30.8 1.4 0.028 12.5 0.0 4.2 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO19564.1 - 8e-06 24.3 0.1 0.036 12.3 0.0 2.8 1 1 3 4 4 4 3 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO19564.1 - 2.7e-05 23.1 5.9 0.18 10.5 0.7 4.6 1 1 2 3 3 3 2 Nup133 N terminal like PQQ_2 PF13360.1 ETO19564.1 - 0.00055 19.4 0.2 0.057 12.8 0.1 3.0 1 1 1 2 2 2 2 PQQ-like domain Hira PF07569.6 ETO19564.1 - 0.00089 18.5 1.4 1.7 7.8 0.0 4.8 1 1 5 6 6 6 1 TUP1-like enhancer of split PQQ PF01011.16 ETO19564.1 - 0.0019 17.6 0.0 13 5.4 0.0 4.5 5 0 0 5 5 5 0 PQQ enzyme repeat DUF4221 PF13970.1 ETO19564.1 - 0.0042 16.4 0.0 4.4 6.5 0.0 2.9 1 1 2 3 3 3 2 Domain of unknown function (DUF4221) DUF1258 PF06869.7 ETO19564.1 - 0.011 14.8 0.4 1.4 7.9 0.0 2.8 1 1 3 4 4 4 0 Protein of unknown function (DUF1258) PLD_C PF12357.3 ETO19564.1 - 0.015 14.7 0.1 30 4.2 0.0 4.3 5 0 0 5 5 5 0 Phospholipase D C terminal Me-amine-dh_H PF06433.6 ETO19564.1 - 0.048 12.2 0.0 0.73 8.4 0.0 2.4 3 0 0 3 3 3 0 Methylamine dehydrogenase heavy chain (MADH) Draxin PF15550.1 ETO19565.1 - 1.2 8.7 10.8 1.5 8.4 7.5 1.1 1 0 0 1 1 1 0 Draxin Peptidase_S64 PF08192.6 ETO19565.1 - 1.8 6.7 25.5 2.1 6.5 17.7 1.0 1 0 0 1 1 1 0 Peptidase family S64 CENP-Q PF13094.1 ETO19565.1 - 1.9 8.4 12.5 0.42 10.6 6.3 1.6 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Med5 PF08689.5 ETO19565.1 - 2.2 5.8 9.2 2.6 5.5 6.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit Med5 Hamartin PF04388.7 ETO19565.1 - 3.1 6.3 12.5 3.2 6.3 8.6 1.0 1 0 0 1 1 1 0 Hamartin protein DUF4603 PF15376.1 ETO19565.1 - 5.2 4.1 22.5 6.2 3.8 15.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Ras PF00071.17 ETO19566.1 - 4.1e-38 130.3 0.4 2.1e-35 121.5 0.3 2.1 1 1 0 1 1 1 1 Ras family Miro PF08477.8 ETO19566.1 - 6.9e-16 58.8 0.2 2.4e-15 57.0 0.1 1.8 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO19566.1 - 1.8e-08 33.8 1.1 1.9e-06 27.2 0.8 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETO19566.1 - 9.7e-07 28.7 0.1 1.4e-06 28.2 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 ETO19566.1 - 0.0001 21.5 0.2 0.0002 20.6 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Arch_ATPase PF01637.13 ETO19566.1 - 0.0014 18.3 0.3 0.002 17.8 0.2 1.3 1 1 0 1 1 1 1 Archaeal ATPase SRPRB PF09439.5 ETO19566.1 - 0.01 15.0 0.3 0.028 13.6 0.2 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit RST PF12174.3 ETO19566.1 - 0.011 15.5 0.4 0.052 13.3 0.0 2.1 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain AAA_14 PF13173.1 ETO19566.1 - 0.02 14.7 0.5 0.22 11.4 0.4 2.1 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 ETO19566.1 - 0.062 12.7 0.2 0.16 11.3 0.1 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF258 PF03193.11 ETO19566.1 - 0.069 12.3 0.1 0.17 11.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 CDV3 PF15359.1 ETO19567.1 - 0.088 12.8 4.2 0.11 12.6 2.9 1.3 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 Zip PF02535.17 ETO19567.1 - 0.39 9.6 8.5 0.43 9.5 5.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF506 PF04720.7 ETO19567.1 - 2.7 7.5 6.5 3.3 7.3 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Lactamase_B PF00753.22 ETO19568.1 - 0.015 14.9 15.3 0.031 13.9 10.6 1.6 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETO19568.1 - 0.15 11.5 12.8 1 8.8 9.6 1.6 1 1 1 2 2 2 0 Beta-lactamase superfamily domain Zip PF02535.17 ETO19568.1 - 0.52 9.2 2.6 0.52 9.2 1.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1796 PF08795.5 ETO19568.1 - 8.9 5.9 7.8 19 4.8 5.4 1.9 1 1 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) Pkinase PF00069.20 ETO19570.1 - 3e-54 183.9 0.1 5e-54 183.1 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO19570.1 - 1.7e-24 86.3 0.2 4.8e-24 84.8 0.1 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 ETO19570.1 - 1.2e-23 80.5 9.9 1.5e-06 27.0 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 ETO19570.1 - 1.7e-18 66.5 7.8 1.1e-09 38.3 0.0 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 ETO19570.1 - 2.1e-18 64.7 8.3 4.2e-07 28.9 0.1 4.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 ETO19570.1 - 6.5e-17 59.8 11.8 1.9e-06 27.2 0.3 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 ETO19570.1 - 9.1e-15 54.0 7.6 0.0013 18.2 0.0 4.5 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 ETO19570.1 - 1.9e-08 34.2 1.9 0.0006 19.8 0.0 4.0 2 2 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Kdo PF06293.9 ETO19570.1 - 8.4e-05 21.7 0.0 0.00016 20.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 ETO19570.1 - 0.00013 21.3 0.2 0.0004 19.7 0.1 1.9 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 ETO19570.1 - 0.0031 17.2 0.0 0.011 15.5 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 ETO19570.1 - 0.033 13.1 0.0 0.1 11.5 0.0 1.7 1 1 0 1 1 1 0 Kinase-like EF-hand_4 PF12763.2 ETO19570.1 - 0.14 11.8 8.4 3.3 7.4 0.1 4.3 2 1 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand PT PF04886.7 ETO19571.1 - 0.00013 21.2 21.2 0.0075 15.5 14.7 2.3 1 1 0 1 1 1 1 PT repeat Beta_helix PF13229.1 ETO19571.1 - 0.0015 18.2 7.7 0.0015 18.2 5.3 1.8 2 1 0 2 2 2 1 Right handed beta helix region NosD PF05048.8 ETO19571.1 - 1.9 7.5 18.8 0.013 14.6 5.6 2.1 2 0 0 2 2 2 0 Periplasmic copper-binding protein (NosD) G-alpha PF00503.15 ETO19572.1 - 1.5e-33 116.0 0.1 1.9e-33 115.7 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO19572.1 - 1.5e-05 24.3 0.0 2.3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family CRT-like PF08627.5 ETO19572.1 - 0.03 14.2 0.1 0.043 13.7 0.1 1.2 1 0 0 1 1 1 0 CRT-like G-alpha PF00503.15 ETO19573.1 - 5.3e-34 117.5 4.2 5.9e-34 117.4 2.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit UPF0113 PF03657.8 ETO19573.1 - 0.01 15.4 0.2 0.022 14.4 0.1 1.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0113) Thioredoxin PF00085.15 ETO19574.1 - 2.4e-22 78.6 0.0 5.6e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin PUL PF08324.6 ETO19574.1 - 5.7e-16 58.1 5.2 9.3e-16 57.4 3.6 1.3 1 0 0 1 1 1 1 PUL domain Thioredoxin_2 PF13098.1 ETO19574.1 - 0.00055 20.1 0.1 0.0027 17.9 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 ETO19574.1 - 0.00058 19.8 0.0 0.0016 18.3 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.1 ETO19574.1 - 0.0067 16.5 0.1 0.025 14.6 0.0 2.0 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 ETO19574.1 - 0.0068 16.0 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family PrpR_N PF06506.6 ETO19574.1 - 0.1 11.9 0.1 0.5 9.7 0.0 2.0 2 1 0 2 2 2 0 Propionate catabolism activator RRM_5 PF13893.1 ETO19575.1 - 8.3e-09 35.1 2.1 6.4e-08 32.3 1.5 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 ETO19575.1 - 5e-07 29.2 7.5 0.00055 19.5 0.2 2.9 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.17 ETO19575.1 - 2.2e-05 23.9 1.5 0.00031 20.3 1.1 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO19575.1 - 0.0067 16.3 0.6 0.017 15.0 0.4 1.7 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETO19575.1 - 0.06 13.1 0.4 0.88 9.3 0.1 3.0 3 1 0 3 3 3 0 Nup53/35/40-type RNA recognition motif DUF1987 PF09345.5 ETO19575.1 - 0.64 9.8 2.4 21 5.0 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1987) CBM_19 PF03427.8 ETO19575.1 - 0.94 9.2 3.9 0.85 9.4 0.5 2.2 2 0 0 2 2 2 0 Carbohydrate binding domain (family 19) MMPL PF03176.10 ETO19576.1 - 6e-29 100.7 5.2 6e-29 100.7 3.6 1.7 2 0 0 2 2 2 1 MMPL family XK-related PF09815.4 ETO19577.1 - 5.6e-09 35.4 2.0 5.6e-09 35.4 1.4 1.7 2 1 0 2 2 2 1 XK-related protein Exonuc_VII_L PF02601.10 ETO19578.1 - 1 8.4 11.7 1.7 7.7 8.1 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Glyco_hydro_3_C PF01915.17 ETO19579.1 - 5.7e-09 35.8 0.1 8.9e-09 35.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETO19579.1 - 0.00041 20.2 0.0 0.00066 19.5 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain CDP-OH_P_transf PF01066.16 ETO19580.1 - 3.2e-13 49.8 11.1 1e-12 48.2 7.7 2.2 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase OTOS PF15182.1 ETO19580.1 - 0.0014 18.2 0.3 0.0033 17.0 0.2 1.6 1 0 0 1 1 1 1 Otospiralin RRM_1 PF00076.17 ETO19581.1 - 1.2e-05 24.8 0.0 2.4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO19581.1 - 0.0078 16.1 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Syntaxin-6_N PF09177.6 ETO19581.1 - 4 7.9 7.2 3.4 8.1 0.4 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF3439 PF11921.3 ETO19582.1 - 0.14 11.8 4.1 0.24 11.1 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 ETO19582.1 - 1.2 7.0 7.7 1.3 6.8 5.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MATH PF00917.21 ETO19582.1 - 6.5 7.0 6.9 12 6.2 4.8 1.6 1 1 0 1 1 1 0 MATH domain VWA_2 PF13519.1 ETO19583.1 - 1.3e-23 84.0 0.2 1.6e-23 83.6 0.2 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 ETO19583.1 - 4.8e-13 49.2 0.1 7.1e-13 48.6 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 ETO19583.1 - 3.4e-06 27.0 0.1 5.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_3 PF13768.1 ETO19583.1 - 1.1e-05 25.1 0.1 2.6e-05 23.9 0.1 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain Flavodoxin_NdrI PF07972.6 ETO19583.1 - 0.048 13.5 0.0 6.6 6.6 0.0 2.4 2 0 0 2 2 2 0 NrdI Flavodoxin like VWA_CoxE PF05762.9 ETO19583.1 - 0.35 9.9 1.9 6.3 5.8 1.3 2.1 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein CTP_transf_2 PF01467.21 ETO19585.1 - 1.1e-15 58.0 1.1 2.1e-09 37.6 0.2 4.5 2 2 0 2 2 2 2 Cytidylyltransferase FERM_M PF00373.13 ETO19585.1 - 0.093 12.9 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 FERM central domain PIH1 PF08190.7 ETO19587.1 - 7e-14 51.9 16.2 3e-11 43.3 2.1 3.8 4 1 0 4 4 4 2 pre-RNA processing PIH1/Nop17 CS PF04969.11 ETO19587.1 - 0.00054 20.4 0.9 0.00054 20.4 0.6 2.9 3 0 0 3 3 3 1 CS domain Peptidase_S49_N PF08496.5 ETO19587.1 - 9.2 6.0 8.7 42 3.8 4.0 2.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Vps39_1 PF10366.4 ETO19589.1 - 0.00032 20.6 17.3 0.00044 20.2 0.5 5.6 4 1 1 5 5 5 3 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 ETO19589.1 - 0.011 15.8 0.4 0.011 15.8 0.3 3.1 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 Phostensin_N PF13916.1 ETO19589.1 - 0.99 9.4 5.9 0.72 9.8 0.3 2.7 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal zf-RING_2 PF13639.1 ETO19590.1 - 3.1e-14 52.4 5.9 5.6e-14 51.6 4.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 ETO19590.1 - 1.3e-08 34.8 4.3 2.9e-08 33.6 3.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 ETO19590.1 - 8.5e-07 28.5 3.2 1.3e-06 27.9 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO19590.1 - 1.3e-06 28.3 5.9 2.1e-06 27.6 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO19590.1 - 7e-06 25.6 6.7 1.3e-05 24.7 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO19590.1 - 0.0007 19.2 5.1 0.0014 18.3 3.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.3 ETO19590.1 - 0.0018 18.1 5.9 0.0081 16.0 4.1 2.1 1 1 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 ETO19590.1 - 0.0027 17.5 1.9 0.0059 16.4 1.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 ETO19590.1 - 0.012 15.1 4.0 0.022 14.3 2.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF899 PF05988.7 ETO19590.1 - 0.037 13.4 0.2 0.082 12.3 0.2 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) Endonuclease_7 PF02945.10 ETO19590.1 - 0.038 13.6 1.0 0.085 12.5 0.7 1.6 1 0 0 1 1 1 0 Recombination endonuclease VII Dicty_REP PF05086.7 ETO19590.1 - 0.053 11.2 18.5 0.079 10.7 12.8 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RINGv PF12906.2 ETO19590.1 - 0.1 12.6 3.7 0.26 11.3 2.6 1.7 1 1 0 1 1 1 0 RING-variant domain zf-Nse PF11789.3 ETO19590.1 - 0.13 11.8 2.3 0.24 10.9 1.6 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 ETO19590.1 - 0.16 11.6 4.8 0.42 10.3 3.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_1 PF14446.1 ETO19590.1 - 0.3 10.8 3.7 0.19 11.4 0.6 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF1272 PF06906.6 ETO19590.1 - 0.42 10.5 2.8 0.79 9.6 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING-like PF08746.6 ETO19590.1 - 0.53 10.3 4.5 0.97 9.4 3.1 1.5 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 ETO19590.1 - 0.64 9.7 5.3 1.4 8.6 3.7 1.6 1 0 0 1 1 1 0 PHD-finger Glycos_transf_1 PF00534.15 ETO19593.1 - 1.7e-25 89.4 0.0 3.7e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 ABC_tran PF00005.22 ETO19593.1 - 5e-20 72.2 0.1 1.6e-19 70.5 0.0 1.9 1 1 0 1 1 1 1 ABC transporter Glyco_trans_1_4 PF13692.1 ETO19593.1 - 3.1e-09 37.1 0.0 6.5e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 ETO19593.1 - 0.00081 19.6 0.0 0.0018 18.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 AAA_21 PF13304.1 ETO19593.1 - 0.0014 18.7 0.1 0.0014 18.7 0.0 4.2 2 2 2 4 4 4 1 AAA domain Miro PF08477.8 ETO19593.1 - 0.011 16.2 0.0 0.028 14.8 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein DUF3584 PF12128.3 ETO19593.1 - 0.022 12.1 0.3 0.032 11.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_17 PF13207.1 ETO19593.1 - 0.062 14.1 0.0 0.21 12.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 ETO19593.1 - 0.074 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.1 ETO19593.1 - 0.22 11.0 0.0 0.47 10.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 ETO19593.1 - 0.56 10.4 5.6 3.2 8.0 3.9 2.4 1 1 0 1 1 1 0 AAA domain MannoseP_isomer PF01050.13 ETO19594.1 - 5.2e-56 188.4 3.6 5.2e-56 188.4 2.5 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase NTP_transferase PF00483.18 ETO19594.1 - 8.3e-44 149.7 0.6 2.4e-43 148.2 0.1 2.0 2 1 0 2 2 2 1 Nucleotidyl transferase Cupin_2 PF07883.6 ETO19594.1 - 6.9e-09 35.0 1.1 9.9e-09 34.5 0.2 1.7 2 0 0 2 2 2 1 Cupin domain CENP-C_C PF11699.3 ETO19594.1 - 0.025 14.5 0.2 0.06 13.3 0.1 1.8 2 0 0 2 2 2 0 Mif2/CENP-C like DUF3910 PF13049.1 ETO19594.1 - 0.085 12.9 0.7 0.56 10.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3910) Pkinase PF00069.20 ETO19595.1 - 2.7e-25 89.0 0.5 1.9e-24 86.2 0.3 2.0 1 1 0 1 1 1 1 Protein kinase domain PCNP PF15473.1 ETO19595.1 - 5.1 7.3 7.9 28 4.9 5.5 2.1 1 1 0 1 1 1 0 PEST, proteolytic signal-containing nuclear protein family Ank_2 PF12796.2 ETO19596.1 - 2.2e-21 76.0 5.3 4.7e-16 58.9 0.1 3.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO19596.1 - 2.4e-17 62.5 1.2 5.2e-08 32.8 0.1 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO19596.1 - 4.3e-17 62.1 0.6 2e-10 40.9 0.0 3.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 ETO19596.1 - 6.1e-15 54.1 0.9 0.00015 21.4 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 ETO19596.1 - 1e-10 40.7 1.5 0.13 12.6 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat CTP_transf_3 PF02348.14 ETO19596.1 - 0.0089 15.6 0.4 0.013 15.1 0.3 1.3 1 0 0 1 1 1 1 Cytidylyltransferase 2OG-FeII_Oxy_3 PF13640.1 ETO19597.1 - 0.00029 21.2 0.0 0.00044 20.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 ETO19597.1 - 0.027 14.7 0.0 0.044 14.0 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Kelch_4 PF13418.1 ETO19599.1 - 2.4e-08 33.6 1.9 0.00028 20.5 0.1 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO19599.1 - 1.1e-07 31.7 1.5 0.012 15.7 0.1 4.1 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO19599.1 - 7.4e-06 25.4 5.0 0.016 14.7 0.0 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO19599.1 - 7.2e-05 22.8 0.0 0.0082 16.2 0.0 2.9 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO19599.1 - 0.0035 17.2 0.2 7.1 6.7 0.0 4.0 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 ETO19599.1 - 0.049 13.4 2.8 5.3 6.9 0.0 4.1 5 0 0 5 5 5 0 Kelch motif FH2 PF02181.18 ETO19601.1 - 7.6e-43 146.8 7.1 7.6e-43 146.8 4.9 4.1 3 2 0 3 3 3 1 Formin Homology 2 Domain SEP PF08059.8 ETO19602.1 - 2.8e-12 46.7 0.7 5.5e-10 39.4 0.5 2.9 1 1 0 1 1 1 1 SEP domain UBX PF00789.15 ETO19602.1 - 0.0011 18.9 0.0 0.011 15.8 0.0 2.3 1 1 0 1 1 1 1 UBX domain COG2 PF06148.6 ETO19603.1 - 0.0035 17.2 24.4 0.11 12.3 2.0 3.3 1 1 2 3 3 3 2 COG (conserved oligomeric Golgi) complex component, COG2 APG6 PF04111.7 ETO19603.1 - 0.0037 16.3 44.9 0.017 14.1 11.1 2.0 1 1 1 2 2 2 2 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 ETO19603.1 - 0.0055 16.5 47.5 0.013 15.3 18.5 2.4 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 ETO19603.1 - 0.0068 15.6 10.9 0.12 11.5 2.7 2.2 1 1 1 2 2 2 2 Reovirus sigma C capsid protein AAA_13 PF13166.1 ETO19603.1 - 0.0097 14.4 34.9 0.014 13.9 24.2 1.2 1 0 0 1 1 1 1 AAA domain Myosin_tail_1 PF01576.14 ETO19603.1 - 0.096 10.3 44.4 2.3 5.8 17.4 2.2 1 1 0 1 1 1 0 Myosin tail IncA PF04156.9 ETO19603.1 - 0.13 11.8 47.8 0.92 9.0 13.8 2.1 1 1 1 2 2 2 0 IncA protein Filament PF00038.16 ETO19603.1 - 0.29 10.5 39.1 0.16 11.4 7.6 2.6 1 1 1 2 2 2 0 Intermediate filament protein MscS_porin PF12795.2 ETO19603.1 - 0.38 10.0 42.6 1.4 8.1 2.7 3.0 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain ERM PF00769.14 ETO19603.1 - 0.66 9.4 46.8 1.2 8.6 17.9 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family EzrA PF06160.7 ETO19603.1 - 0.89 7.6 34.7 1.5 6.9 24.0 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA WEMBL PF05701.6 ETO19603.1 - 0.9 7.9 38.7 1.6 7.0 26.8 1.4 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Fez1 PF06818.10 ETO19603.1 - 0.91 9.5 35.8 1.5 8.7 4.9 3.0 1 1 2 3 3 3 0 Fez1 TPR_MLP1_2 PF07926.7 ETO19603.1 - 0.95 9.2 46.1 0.22 11.2 12.7 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Laminin_II PF06009.7 ETO19603.1 - 1.1 8.9 27.7 1.1 9.0 5.6 3.0 1 1 2 3 3 3 0 Laminin Domain II DUF3584 PF12128.3 ETO19603.1 - 1.5 6.0 39.0 2.1 5.5 27.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MAD PF05557.8 ETO19603.1 - 2.9 5.8 47.3 0.24 9.4 10.5 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein GAS PF13851.1 ETO19603.1 - 3 6.9 47.3 1.5 7.9 9.0 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FlaC_arch PF05377.6 ETO19603.1 - 3 7.7 28.5 1.8 8.5 0.8 4.8 2 2 2 5 5 5 0 Flagella accessory protein C (FlaC) DUF4618 PF15397.1 ETO19603.1 - 4.5 6.5 41.7 0.63 9.3 6.8 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) Bacillus_HBL PF05791.6 ETO19603.1 - 6.1 6.1 30.2 0.07 12.4 1.2 3.3 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Cortex-I_coil PF09304.5 ETO19603.1 - 6.9 6.7 40.8 0.13 12.2 8.2 3.1 1 1 2 3 3 3 0 Cortexillin I, coiled coil DUF4200 PF13863.1 ETO19603.1 - 7.3 6.5 49.3 2.6 8.0 10.4 3.2 2 1 0 3 3 3 0 Domain of unknown function (DUF4200) DUF812 PF05667.6 ETO19603.1 - 8.5 4.7 37.7 11 4.3 26.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) CENP-Q PF13094.1 ETO19603.1 - 9.3 6.2 43.5 6.6 6.7 9.1 2.4 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Myosin_tail_1 PF01576.14 ETO19604.1 - 2.1e-06 25.8 17.6 2.1e-06 25.8 12.2 1.9 2 0 0 2 2 2 1 Myosin tail ADIP PF11559.3 ETO19604.1 - 7.9e-05 22.5 32.6 0.055 13.3 6.3 4.1 2 1 2 4 4 4 3 Afadin- and alpha -actinin-Binding IncA PF04156.9 ETO19604.1 - 0.00028 20.5 35.1 0.069 12.7 4.1 3.3 2 1 1 3 3 3 3 IncA protein DUF869 PF05911.6 ETO19604.1 - 0.0011 17.2 25.2 0.0013 17.0 8.1 3.0 2 1 1 3 3 3 2 Plant protein of unknown function (DUF869) DUF4201 PF13870.1 ETO19604.1 - 0.0064 15.9 25.6 0.027 13.8 12.9 3.2 2 1 1 3 3 3 1 Domain of unknown function (DUF4201) ATG16 PF08614.6 ETO19604.1 - 0.0093 15.8 24.7 0.08 12.7 12.0 2.4 2 1 0 2 2 2 2 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 ETO19604.1 - 0.012 14.8 1.9 0.047 12.8 0.2 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF3573 PF12097.3 ETO19604.1 - 0.071 11.7 8.5 0.96 7.9 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) GAS PF13851.1 ETO19604.1 - 0.081 12.1 27.9 1.7 7.7 0.1 3.2 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding THP2 PF09432.5 ETO19604.1 - 0.15 11.8 6.7 0.62 9.9 0.8 2.7 1 1 1 2 2 2 0 Tho complex subunit THP2 bZIP_1 PF00170.16 ETO19604.1 - 0.19 11.6 0.3 0.19 11.6 0.2 4.8 2 1 1 4 4 3 0 bZIP transcription factor DUF972 PF06156.8 ETO19604.1 - 0.41 11.0 0.1 0.41 11.0 0.1 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF972) CENP-F_leu_zip PF10473.4 ETO19604.1 - 0.44 10.4 32.4 0.24 11.2 5.4 3.8 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF342 PF03961.8 ETO19604.1 - 0.84 7.9 19.1 13 4.0 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF342) FUSC PF04632.7 ETO19604.1 - 1.3 7.3 3.1 2 6.7 2.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family APG6 PF04111.7 ETO19604.1 - 1.8 7.5 32.1 1.4 7.8 0.2 3.0 2 1 0 2 2 2 0 Autophagy protein Apg6 Exonuc_VII_L PF02601.10 ETO19604.1 - 1.9 7.6 15.9 9.7 5.2 0.0 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit Tropomyosin PF00261.15 ETO19604.1 - 2.1 7.4 25.4 0.75 8.8 9.5 2.9 2 1 0 3 3 3 0 Tropomyosin Baculo_PEP_C PF04513.7 ETO19604.1 - 2.2 8.0 12.1 0.77 9.5 1.4 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 ETO19604.1 - 2.6 7.8 9.1 30 4.4 2.2 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Bap31 PF05529.7 ETO19604.1 - 2.7 7.3 20.5 3.9 6.8 1.7 3.4 3 0 0 3 3 3 0 B-cell receptor-associated protein 31-like Spc24 PF08286.6 ETO19604.1 - 2.7 7.6 0.0 2.7 7.6 0.0 4.1 2 1 1 3 3 2 0 Spc24 subunit of Ndc80 Syntaxin-6_N PF09177.6 ETO19604.1 - 2.8 8.4 15.2 5.8 7.3 4.0 3.6 2 1 1 3 3 3 0 Syntaxin 6, N-terminal PEARLI-4 PF05278.7 ETO19604.1 - 3.1 7.1 16.3 0.22 10.8 3.1 3.0 2 1 1 3 3 3 0 Arabidopsis phospholipase-like protein (PEARLI 4) Acetyltransf_11 PF13720.1 ETO19604.1 - 3.1 8.0 8.7 1.2 9.3 0.2 3.3 3 1 1 4 4 4 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Macoilin PF09726.4 ETO19604.1 - 3.6 5.7 18.2 1.1 7.4 8.4 2.2 2 0 0 2 2 2 0 Transmembrane protein Laminin_I PF06008.9 ETO19604.1 - 4.2 6.6 20.8 0.87 8.8 3.1 3.1 2 1 1 3 3 3 0 Laminin Domain I EMP24_GP25L PF01105.19 ETO19604.1 - 6.8 6.3 11.7 0.21 11.3 2.1 2.5 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD Seryl_tRNA_N PF02403.17 ETO19604.1 - 8.8 6.3 19.1 0.24 11.4 3.6 3.1 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DivIVA PF05103.8 ETO19604.1 - 8.9 6.3 21.8 1.4 8.9 2.9 4.1 2 1 2 4 4 4 0 DivIVA protein BLOC1_2 PF10046.4 ETO19604.1 - 10 6.3 14.5 0.76 9.9 1.0 3.3 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fez1 PF06818.10 ETO19605.1 - 0.023 14.6 1.8 0.048 13.6 1.3 1.5 1 1 0 1 1 1 0 Fez1 FAM24 PF15193.1 ETO19605.1 - 0.084 13.0 0.4 1.3 9.2 0.2 2.5 2 0 0 2 2 2 0 FAM24 family DUF1043 PF06295.7 ETO19605.1 - 0.36 10.4 4.2 0.24 11.0 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) BLOC1_2 PF10046.4 ETO19605.1 - 8.4 6.6 9.3 0.83 9.8 2.8 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PAT1 PF09770.4 ETO19607.1 - 0.0064 14.8 29.3 0.0086 14.3 20.3 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF4366 PF14283.1 ETO19607.1 - 0.012 15.0 1.3 0.012 15.0 0.9 4.5 3 2 2 5 5 5 0 Domain of unknown function (DUF4366) AvrL567-A PF11529.3 ETO19607.1 - 0.095 12.6 0.3 0.18 11.8 0.2 1.4 1 0 0 1 1 1 0 Melampsora lini avirulence protein AvrL567-A zf-RING_6 PF14835.1 ETO19607.1 - 0.99 9.2 3.7 1.8 8.3 2.6 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein OAD_gamma PF04277.8 ETO19607.1 - 9.8 6.6 9.3 6.7 7.1 0.0 3.6 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain OSCP PF00213.13 ETO19608.1 - 4.7e-18 65.6 0.1 4.7e-18 65.6 0.1 3.7 6 0 0 6 6 6 2 ATP synthase delta (OSCP) subunit FYVE PF01363.16 ETO19610.1 - 9.3e-07 28.6 2.1 1.5e-06 27.9 0.9 1.8 2 0 0 2 2 2 1 FYVE zinc finger PH PF00169.24 ETO19610.1 - 2.7e-06 27.5 0.1 5e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 PH domain MucB_RseB PF03888.9 ETO19610.1 - 0.053 12.5 0.1 0.082 11.9 0.1 1.5 1 1 0 1 1 1 0 MucB/RseB family SID-1_RNA_chan PF13965.1 ETO19611.1 - 4 5.4 6.3 1.4 6.9 0.4 2.0 1 1 0 2 2 2 0 dsRNA-gated channel SID-1 Gp_dh_C PF02800.15 ETO19612.1 - 4.6e-69 230.8 0.0 6.3e-69 230.4 0.0 1.1 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Semialdhyde_dhC PF02774.13 ETO19612.1 - 0.058 13.2 0.0 0.13 12.0 0.0 1.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain DUF2207 PF09972.4 ETO19613.1 - 0.12 10.9 4.0 0.18 10.3 2.8 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Orbi_NS3 PF01616.11 ETO19613.1 - 0.36 9.7 3.3 0.18 10.7 0.4 1.8 2 0 0 2 2 2 0 Orbivirus NS3 DUF4131 PF13567.1 ETO19613.1 - 7.8 5.8 10.3 14 5.0 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) PBP1_TM PF14812.1 ETO19614.1 - 5.9 7.2 8.0 9.1 6.6 0.4 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PIG-L PF02585.12 ETO19615.1 - 6.8e-16 58.9 0.0 9.9e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase ThiI PF02568.9 ETO19615.1 - 0.099 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Pkinase PF00069.20 ETO19616.1 - 0.0004 19.6 0.4 0.0018 17.5 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Daxx PF03344.10 ETO19616.1 - 0.031 12.7 7.7 0.039 12.4 5.3 1.0 1 0 0 1 1 1 0 Daxx Family NST1 PF13945.1 ETO19616.1 - 1 9.4 9.9 0.079 13.0 3.0 1.8 2 0 0 2 2 2 0 Salt tolerance down-regulator Ion_trans_N PF08412.5 ETO19617.1 - 0.037 13.3 4.4 0.081 12.2 3.1 1.5 1 0 0 1 1 1 0 Ion transport protein N-terminal V_ATPase_I PF01496.14 ETO19618.1 - 4e-46 157.2 10.4 4.4e-25 87.6 1.2 2.2 2 0 0 2 2 2 2 V-type ATPase 116kDa subunit family PBP1_TM PF14812.1 ETO19618.1 - 6.6 7.1 9.3 1.5 9.1 3.0 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Papo_T_antigen PF02380.10 ETO19619.1 - 0.00022 21.0 1.0 0.00022 21.0 0.7 1.8 2 0 0 2 2 2 1 T-antigen specific domain Ydc2-catalyt PF09159.5 ETO19619.1 - 0.0096 15.4 0.1 0.013 15.0 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SSP160 PF06933.6 ETO19620.1 - 0.079 10.9 12.1 0.089 10.7 8.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TMEM154 PF15102.1 ETO19620.1 - 0.15 11.7 1.6 0.25 11.0 1.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family Dicty_REP PF05086.7 ETO19620.1 - 0.23 9.1 7.1 0.3 8.7 4.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 ETO19620.1 - 0.55 9.9 18.8 0.96 9.2 13.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Tir_receptor_C PF07489.6 ETO19620.1 - 2.1 8.0 7.0 3.4 7.3 4.9 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus gpUL132 PF11359.3 ETO19620.1 - 5.4 6.2 10.7 8.1 5.6 7.4 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 CobT PF06213.7 ETO19621.1 - 0.0017 17.5 3.0 0.0017 17.5 2.1 3.6 2 1 0 3 3 3 1 Cobalamin biosynthesis protein CobT Nucleoporin2 PF04096.9 ETO19622.1 - 1.4e-21 76.7 0.0 5.5e-15 55.4 0.0 2.4 2 0 0 2 2 2 2 Nucleoporin autopeptidase TRAPPC-Trs85 PF12739.2 ETO19626.1 - 0.045 12.4 0.2 0.069 11.7 0.1 1.2 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit ApbA_C PF08546.6 ETO19627.1 - 1.4e-30 105.8 0.0 2.2e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 ETO19627.1 - 6.5e-16 58.1 0.4 1.3e-15 57.1 0.1 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA TPR_11 PF13414.1 ETO19628.1 - 1.8e-14 53.1 4.9 7.2e-13 47.9 0.3 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETO19628.1 - 1.3e-11 43.5 7.4 1.9e-07 30.4 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO19628.1 - 2.6e-10 39.4 4.9 0.00015 21.4 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 ETO19628.1 - 3e-07 30.2 1.6 5.5e-05 23.0 0.4 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO19628.1 - 0.0018 17.9 11.6 0.0048 16.5 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3808 PF10300.4 ETO19628.1 - 0.0024 16.5 1.9 0.0024 16.5 1.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) Fis1_TPR_C PF14853.1 ETO19628.1 - 0.053 13.4 1.4 24 4.9 0.1 3.7 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.4 ETO19628.1 - 0.081 12.1 0.0 8.4 5.7 0.0 2.7 2 0 0 2 2 2 0 SHNi-TPR TPR_7 PF13176.1 ETO19628.1 - 0.11 12.3 0.2 4.2 7.3 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat Tom22 PF04281.8 ETO19629.1 - 0.0016 18.0 5.3 0.05 13.1 3.7 2.2 1 1 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Mhr1 PF12829.2 ETO19629.1 - 0.0068 16.2 1.7 0.014 15.2 1.2 1.4 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination Vpu PF00558.14 ETO19629.1 - 0.06 12.9 0.2 0.06 12.9 0.2 2.7 2 1 0 2 2 2 0 Vpu protein NdhL PF10716.4 ETO19629.1 - 0.13 12.0 0.4 0.21 11.3 0.3 1.3 1 0 0 1 1 1 0 NADH dehydrogenase transmembrane subunit DUF2854 PF11016.3 ETO19629.1 - 0.72 9.3 3.7 1.7 8.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2854) DUF2762 PF10960.3 ETO19629.1 - 4.2 7.1 9.0 13 5.5 0.6 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2762) Polysacc_synt_4 PF04669.8 ETO19630.1 - 1.5e-05 24.4 0.0 2.5e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis PUF PF00806.14 ETO19631.1 - 5.2e-17 60.2 9.7 0.00033 19.9 0.1 4.6 4 0 0 4 4 4 4 Pumilio-family RNA binding repeat CPL PF08144.6 ETO19631.1 - 0.072 12.9 0.2 1.5 8.6 0.1 2.6 1 1 1 2 2 2 0 CPL (NUC119) domain PUF PF00806.14 ETO19632.1 - 6.7e-18 63.0 1.7 7.3e-06 25.1 0.1 3.3 3 0 0 3 3 3 3 Pumilio-family RNA binding repeat BRCT PF00533.21 ETO19632.1 - 0.012 15.7 0.3 0.021 14.9 0.2 1.7 1 1 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain GED PF02212.13 ETO19632.1 - 0.03 14.2 1.9 0.85 9.5 0.2 2.3 1 1 1 2 2 2 0 Dynamin GTPase effector domain Ank_2 PF12796.2 ETO19632.1 - 0.04 14.2 0.0 0.14 12.5 0.0 1.9 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) DUF1831 PF08866.5 ETO19632.1 - 0.079 13.2 0.3 7.9 6.7 0.0 2.2 1 1 1 2 2 2 0 Putative amino acid metabolism YqzH PF14164.1 ETO19632.1 - 0.12 12.3 1.2 0.48 10.3 0.1 2.2 2 1 0 2 2 2 0 YqzH-like protein DUF3133 PF11331.3 ETO19633.1 - 0.32 10.6 0.0 0.32 10.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3133) AIF_C PF14721.1 ETO19634.1 - 0.9 9.7 3.5 0.52 10.5 0.5 1.8 1 1 1 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Synaptobrevin PF00957.16 ETO19635.1 - 5.1 6.7 9.1 0.18 11.4 1.1 2.3 3 0 0 3 3 3 0 Synaptobrevin CAP_GLY PF01302.20 ETO19636.1 - 8.8e-08 31.7 0.1 1.8e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain Enkurin PF13864.1 ETO19636.1 - 0.19 11.9 3.2 0.63 10.2 0.2 2.3 2 0 0 2 2 2 0 Calmodulin-binding Ni_hydr_CYTB PF01292.15 ETO19638.1 - 0.0076 15.6 0.0 0.0094 15.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 DUF679 PF05078.7 ETO19638.1 - 0.03 13.9 0.0 0.047 13.3 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF679) Srg PF02118.16 ETO19638.1 - 0.032 13.6 0.0 0.16 11.3 0.0 1.8 1 1 1 2 2 2 0 Srg family chemoreceptor DUF2973 PF11189.3 ETO19638.1 - 0.063 13.0 1.8 1.9 8.2 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2973) Ctr PF04145.10 ETO19639.1 - 0.85 9.6 3.8 18 5.3 0.9 2.6 2 0 0 2 2 2 0 Ctr copper transporter family DUF3807 PF12720.2 ETO19639.1 - 7.2 6.7 20.3 10 6.2 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Metallophos PF00149.23 ETO19640.1 - 4.2e-08 32.8 0.1 8.8e-08 31.7 0.1 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Cyt-b5 PF00173.23 ETO19641.1 - 2.7e-12 46.3 0.0 4.6e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Tmemb_170 PF10190.4 ETO19641.1 - 5.2 7.1 6.8 15 5.6 0.3 2.3 1 1 1 2 2 2 0 Putative transmembrane protein 170 FA_desaturase PF00487.19 ETO19642.1 - 3.7e-29 101.9 17.1 2.7e-28 99.1 11.8 1.9 1 1 0 1 1 1 1 Fatty acid desaturase Vma12 PF11712.3 ETO19642.1 - 1.4 8.6 3.6 4.9 6.8 0.2 2.3 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Ldl_recept_a PF00057.13 ETO19643.1 - 0.032 14.1 3.9 0.072 13.0 0.8 2.5 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A DUF1237 PF06824.6 ETO19644.1 - 0.00086 18.0 0.2 0.0012 17.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) RXT2_N PF08595.6 ETO19644.1 - 1.9 8.2 9.6 0.8 9.4 2.4 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal SPRY PF00622.23 ETO19646.1 - 3.3e-09 36.8 0.2 4.1e-09 36.5 0.1 1.1 1 0 0 1 1 1 1 SPRY domain DUF668 PF05003.7 ETO19647.1 - 0.036 14.2 0.8 0.059 13.5 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF668) Helicase_IV_N PF12462.3 ETO19647.1 - 0.068 12.8 0.9 0.099 12.2 0.6 1.3 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal Paramyxo_C PF01692.13 ETO19647.1 - 0.19 11.3 5.5 0.27 10.8 3.8 1.3 1 1 0 1 1 1 0 Paramyxovirus non-structural protein c SPX PF03105.14 ETO19647.1 - 7.8 6.1 11.9 51 3.5 8.2 1.9 1 1 0 1 1 1 0 SPX domain Acyl_transf_3 PF01757.17 ETO19649.1 - 0.05 12.4 0.8 0.068 12.0 0.6 1.1 1 0 0 1 1 1 0 Acyltransferase family TPR_12 PF13424.1 ETO19650.1 - 2.8e-41 139.3 8.3 1.6e-18 66.3 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO19650.1 - 7.5e-27 92.7 24.0 1.8e-10 40.3 0.3 3.9 2 1 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 ETO19650.1 - 2.6e-25 86.9 25.0 2.7e-07 29.9 0.2 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO19650.1 - 4.6e-22 76.1 15.7 9.8e-06 25.1 0.2 6.2 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 ETO19650.1 - 9.9e-19 65.6 21.3 2.1e-05 23.9 0.6 5.8 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.1 ETO19650.1 - 1.3e-17 62.1 2.7 3.3e-05 23.3 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO19650.1 - 2.2e-15 56.0 0.0 1.8e-05 24.5 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETO19650.1 - 2.4e-10 39.7 1.8 0.011 15.8 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO19650.1 - 5.9e-08 32.6 6.9 0.37 11.3 0.0 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO19650.1 - 1.8e-06 28.4 0.5 0.82 10.4 0.0 4.2 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO19650.1 - 7.5e-06 26.1 0.1 5.1 8.0 0.0 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat MIT PF04212.13 ETO19650.1 - 5.9e-05 22.8 9.7 0.17 11.7 0.1 5.4 5 0 0 5 5 5 2 MIT (microtubule interacting and transport) domain TPR_19 PF14559.1 ETO19650.1 - 0.00086 19.5 0.1 1.5 9.2 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO19650.1 - 0.0035 17.4 12.9 0.43 10.7 1.8 4.0 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 Peptidase_C14 PF00656.17 ETO19650.1 - 0.0081 15.8 0.5 0.46 10.1 0.0 2.4 1 1 0 2 2 2 1 Caspase domain DUF3856 PF12968.2 ETO19650.1 - 0.17 11.6 3.0 5.8 6.7 0.0 3.2 3 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_3 PF07720.7 ETO19650.1 - 0.71 9.7 13.1 1.7 8.4 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4199 PF13858.1 ETO19652.1 - 6.6 6.6 16.3 2 8.3 0.1 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF4199) DUF1011 PF06237.7 ETO19653.1 - 8.3e-14 51.3 5.7 8.3e-14 51.3 4.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1011) Nucleoside_tran PF01733.13 ETO19653.1 - 7.2e-05 22.1 9.1 0.0036 16.5 0.0 2.9 3 0 0 3 3 3 2 Nucleoside transporter DUF1469 PF07332.6 ETO19653.1 - 0.14 11.9 0.1 0.14 11.9 0.1 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1469) SBBP PF06739.6 ETO19653.1 - 0.92 9.3 4.9 3.8 7.3 0.5 2.4 2 0 0 2 2 2 0 Beta-propeller repeat zf-RING_2 PF13639.1 ETO19654.1 - 1e-06 28.4 4.6 1.7e-06 27.7 3.2 1.4 1 0 0 1 1 1 1 Ring finger domain RINGv PF12906.2 ETO19654.1 - 0.00044 20.2 4.2 0.001 19.0 2.9 1.7 1 0 0 1 1 1 1 RING-variant domain zf-rbx1 PF12678.2 ETO19654.1 - 0.0006 19.8 2.6 0.0014 18.7 1.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 ETO19654.1 - 0.0043 16.6 5.3 0.0084 15.7 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 ETO19654.1 - 0.022 14.5 0.4 0.042 13.6 0.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 ETO19654.1 - 0.029 14.0 3.7 0.11 12.2 2.5 2.1 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 ETO19654.1 - 0.031 14.2 5.3 0.061 13.3 3.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MIP-T3 PF10243.4 ETO19654.1 - 0.048 12.1 67.5 0.061 11.7 46.8 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 zf-C3HC4_4 PF15227.1 ETO19654.1 - 0.15 11.9 4.8 0.34 10.8 3.4 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING SAPS PF04499.10 ETO19655.1 - 0.012 14.2 5.5 0.016 13.8 3.8 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PPP4R2 PF09184.6 ETO19655.1 - 0.017 14.6 30.7 0.033 13.7 21.2 1.5 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.7 ETO19655.1 - 0.067 11.1 47.6 0.1 10.4 33.0 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 ETO19655.1 - 0.091 11.8 34.0 0.14 11.2 23.6 1.3 1 0 0 1 1 1 0 BUD22 CENP-T PF15511.1 ETO19655.1 - 0.71 9.0 27.0 1.2 8.3 18.7 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Hid1 PF12722.2 ETO19655.1 - 1.5 6.4 11.3 2.1 5.9 7.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Spore_coat_CotO PF14153.1 ETO19655.1 - 1.6 8.1 10.0 0.71 9.2 5.4 1.6 2 0 0 2 2 2 0 Spore coat protein CotO Astro_capsid PF03115.9 ETO19655.1 - 1.8 6.6 11.8 2.6 6.2 8.2 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF1510 PF07423.6 ETO19655.1 - 4.1 6.7 30.7 8.8 5.6 21.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CENP-B_dimeris PF09026.5 ETO19656.1 - 0.029 14.6 1.4 0.041 14.1 1.0 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 ETO19656.1 - 0.14 11.7 6.6 0.098 12.1 3.5 1.6 2 0 0 2 2 2 0 Nucleoplasmin Sporozoite_P67 PF05642.6 ETO19656.1 - 0.14 9.9 2.4 0.2 9.5 1.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-MYND PF01753.13 ETO19656.1 - 0.24 11.2 6.5 0.42 10.5 4.5 1.3 1 0 0 1 1 1 0 MYND finger Ctr PF04145.10 ETO19657.1 - 0.026 14.5 1.8 0.037 14.0 0.0 2.1 3 0 0 3 3 3 0 Ctr copper transporter family ABC2_membrane_3 PF12698.2 ETO19657.1 - 0.11 11.4 0.3 0.13 11.2 0.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein AMP-binding PF00501.23 ETO19658.1 - 2.8e-17 62.2 0.0 3.2e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ABC2_membrane_5 PF13346.1 ETO19660.1 - 0.0095 15.2 3.7 0.011 15.0 2.6 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein PDR_CDR PF06422.7 ETO19660.1 - 0.76 9.4 4.4 1.6 8.4 3.0 1.6 1 1 0 1 1 1 0 CDR ABC transporter Tmemb_161AB PF10268.4 ETO19660.1 - 1.1 7.6 5.1 0.9 7.9 2.3 1.6 1 1 1 2 2 2 0 Predicted transmembrane protein 161AB PHD PF00628.24 ETO19661.1 - 1.7e-10 40.3 2.7 3.8e-10 39.2 1.8 1.6 1 0 0 1 1 1 1 PHD-finger DUF3270 PF11674.3 ETO19661.1 - 0.39 10.7 2.2 1 9.4 1.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3270) FCP1_C PF09309.5 ETO19662.1 - 0.17 11.1 15.1 0.19 11.0 10.4 1.1 1 0 0 1 1 1 0 FCP1, C-terminal eIF3_subunit PF08597.5 ETO19662.1 - 2.5 7.6 21.8 2.7 7.4 15.1 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit SR-25 PF10500.4 ETO19662.1 - 3.3 7.1 23.1 3.6 6.9 16.0 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SRP-alpha_N PF04086.8 ETO19662.1 - 3.9 6.7 18.5 4.1 6.6 12.8 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal YqfQ PF14181.1 ETO19662.1 - 5.2 7.0 20.9 5.6 6.9 14.5 1.0 1 0 0 1 1 1 0 YqfQ-like protein DUF3807 PF12720.2 ETO19662.1 - 5.6 7.0 17.0 5.9 7.0 11.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Peptidase_M16_C PF05193.16 ETO19663.1 - 1.8e-13 50.5 0.0 3.5e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 ETO19663.1 - 2.6e-10 40.2 0.0 4.1e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Cation_ATPase_C PF00689.16 ETO19664.1 - 0.047 13.2 4.1 0.081 12.4 2.8 1.3 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus RRM_1 PF00076.17 ETO19666.1 - 7.3e-14 51.1 0.0 1.4e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO19666.1 - 5.2e-09 35.9 0.0 1.4e-08 34.5 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO19666.1 - 1.5e-08 34.3 0.0 3.1e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 ETO19666.1 - 0.0015 18.4 0.0 0.0022 17.9 0.0 1.2 1 0 0 1 1 1 1 RNA binding domain F-box-like_2 PF13013.1 ETO19667.1 - 0.064 12.9 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 F-box-like domain DUF4653 PF15546.1 ETO19667.1 - 0.52 9.5 6.7 1.2 8.4 4.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4653) SR-25 PF10500.4 ETO19667.1 - 3.6 6.9 7.5 0.97 8.8 2.8 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Mannosyl_trans3 PF11051.3 ETO19668.1 - 0.045 13.1 0.5 0.074 12.3 0.4 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative RhoGAP PF00620.22 ETO19671.1 - 1.3e-07 31.3 0.0 2.8e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Vmethyltransf_C PF08456.5 ETO19672.1 - 0.025 14.0 1.6 0.03 13.7 1.1 1.1 1 0 0 1 1 1 0 Viral methyltransferase C-terminal DUF605 PF04652.11 ETO19672.1 - 0.11 11.9 17.5 0.12 11.7 12.1 1.0 1 0 0 1 1 1 0 Vta1 like Hid1 PF12722.2 ETO19672.1 - 0.28 8.8 12.7 0.29 8.7 8.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF572 PF04502.8 ETO19672.1 - 0.6 9.2 15.3 0.7 9.0 10.6 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) FAM220 PF15487.1 ETO19672.1 - 2.9 7.1 12.9 3.7 6.8 8.9 1.1 1 0 0 1 1 1 0 FAM220 family Pol_alpha_B_N PF08418.5 ETO19672.1 - 3 7.2 16.2 3.4 7.1 11.2 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Apt1 PF10351.4 ETO19672.1 - 4.3 6.0 9.6 5 5.8 6.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Lin-8 PF03353.10 ETO19672.1 - 4.8 6.3 9.6 5.2 6.2 6.7 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Neur_chan_memb PF02932.11 ETO19672.1 - 6.4 6.5 6.8 7.7 6.3 4.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FYVE PF01363.16 ETO19675.1 - 1.6e-14 53.5 6.9 1.6e-14 53.5 4.8 2.7 3 1 0 3 3 3 1 FYVE zinc finger Sre PF03125.13 ETO19675.1 - 0.21 10.4 1.6 0.34 9.7 1.1 1.3 1 0 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor Hep_core_N PF08290.6 ETO19675.1 - 0.31 10.5 2.9 0.78 9.2 2.0 1.7 1 0 0 1 1 1 0 Hepatitis core protein, putative zinc finger Corona_nucleoca PF00937.13 ETO19675.1 - 0.36 9.7 20.7 0.015 14.2 6.0 2.5 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein Apis_Csd PF11671.3 ETO19676.1 - 0.46 10.2 5.1 0.61 9.8 3.5 1.2 1 0 0 1 1 1 0 Complementary sex determiner protein Secretin_N_2 PF07655.8 ETO19676.1 - 0.74 10.2 12.5 1.1 9.6 8.6 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain Nop14 PF04147.7 ETO19677.1 - 0.017 13.1 10.9 0.02 12.8 7.6 1.1 1 0 0 1 1 1 0 Nop14-like family SGT1 PF07093.6 ETO19677.1 - 0.038 12.3 10.3 0.049 12.0 7.1 1.1 1 0 0 1 1 1 0 SGT1 protein DUF2457 PF10446.4 ETO19677.1 - 0.14 10.8 20.9 0.21 10.2 14.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RXT2_N PF08595.6 ETO19677.1 - 0.23 11.2 8.0 0.41 10.4 5.6 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Pox_RNA_Pol_19 PF05320.7 ETO19677.1 - 0.32 10.7 8.6 0.56 9.9 5.9 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Sigma70_ner PF04546.8 ETO19677.1 - 0.42 10.2 8.5 0.56 9.7 5.9 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region YL1 PF05764.8 ETO19677.1 - 0.53 9.8 10.1 0.74 9.3 7.0 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Ebola_NP PF05505.7 ETO19677.1 - 1.2 7.1 10.7 1.4 6.8 7.4 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein DUF4502 PF14950.1 ETO19677.1 - 1.3 8.1 9.6 1.7 7.7 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4502) CDC45 PF02724.9 ETO19677.1 - 1.6 6.6 11.7 2.2 6.2 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.1 ETO19677.1 - 1.7 8.2 4.9 3.4 7.3 3.4 1.5 1 0 0 1 1 1 0 FAM176 family Sporozoite_P67 PF05642.6 ETO19677.1 - 2.6 5.7 7.9 3.2 5.5 5.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SDA1 PF05285.7 ETO19677.1 - 7.5 5.7 14.0 9.9 5.3 9.7 1.1 1 0 0 1 1 1 0 SDA1 Rhomboid PF01694.17 ETO19678.1 - 7.5e-13 48.7 15.7 7.5e-13 48.7 10.9 2.1 1 1 1 2 2 2 1 Rhomboid family DUF843 PF05814.6 ETO19678.1 - 0.041 13.6 0.7 0.041 13.6 0.5 2.6 3 0 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) DUF1751 PF08551.5 ETO19678.1 - 2.3 8.6 10.4 0.15 12.4 1.6 2.5 3 0 0 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) Reo_sigmaC PF04582.7 ETO19680.1 - 0.0072 15.5 16.6 0.013 14.6 3.6 2.9 1 1 3 4 4 4 3 Reovirus sigma C capsid protein HisKA_3 PF07730.8 ETO19680.1 - 0.56 10.5 4.3 3.6 7.9 0.1 3.6 3 0 0 3 3 3 0 Histidine kinase Metal_resist PF13801.1 ETO19680.1 - 2.4 8.1 6.6 1.2 9.1 0.0 2.9 2 1 1 3 3 3 0 Heavy-metal resistance Spc7 PF08317.6 ETO19680.1 - 7.9 5.0 68.0 0.042 12.5 16.6 3.7 1 1 4 5 5 5 0 Spc7 kinetochore protein TPR_12 PF13424.1 ETO19681.1 - 6.6e-06 25.9 0.0 1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO19681.1 - 0.011 15.4 1.1 0.025 14.3 0.7 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat DUF1307 PF06998.6 ETO19681.1 - 0.045 13.8 0.1 0.052 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1307) GCIP PF13324.1 ETO19683.1 - 0.018 14.2 1.2 0.037 13.2 0.9 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF2927 PF11150.3 ETO19683.1 - 0.88 9.2 6.5 0.69 9.5 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2927) BUD22 PF09073.5 ETO19685.1 - 0.13 11.2 15.3 0.15 11.1 10.6 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 ETO19685.1 - 0.16 9.8 13.0 0.18 9.7 9.0 1.0 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 ETO19685.1 - 0.76 9.0 17.6 0.95 8.7 12.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Utp14 PF04615.8 ETO19685.1 - 1.6 6.7 18.3 1.9 6.5 12.7 1.0 1 0 0 1 1 1 0 Utp14 protein Neur_chan_memb PF02932.11 ETO19685.1 - 3 7.6 5.1 3.8 7.3 3.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Lin-8 PF03353.10 ETO19685.1 - 4.8 6.3 12.6 6 6.0 8.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist MDFI PF15316.1 ETO19685.1 - 5.2 7.0 9.9 7.3 6.5 6.9 1.3 1 0 0 1 1 1 0 MyoD family inhibitor Macoilin PF09726.4 ETO19685.1 - 5.7 5.0 20.2 6.5 4.9 14.0 1.0 1 0 0 1 1 1 0 Transmembrane protein TEX19 PF15553.1 ETO19685.1 - 6 6.7 6.5 6.8 6.5 4.1 1.4 1 1 0 1 1 1 0 Testis-expressed protein 19 Hid1 PF12722.2 ETO19685.1 - 7.1 4.1 14.4 7.9 4.0 10.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CLASP_N PF12348.3 ETO19687.1 - 0.0041 16.4 0.4 0.013 14.9 0.0 1.8 2 0 0 2 2 2 1 CLASP N terminal Cnd1 PF12717.2 ETO19687.1 - 0.033 14.0 0.2 0.086 12.6 0.0 1.7 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 RPN7 PF10602.4 ETO19688.1 - 0.08 12.3 0.1 0.12 11.6 0.0 1.4 1 1 0 1 1 1 0 26S proteasome subunit RPN7 Piwi PF02171.12 ETO19689.1 - 6.2e-17 61.5 0.0 1.7e-16 60.1 0.0 1.7 1 1 1 2 2 2 1 Piwi domain MIP-T3 PF10243.4 ETO19689.1 - 0.048 12.1 80.5 0.077 11.4 55.8 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Mem_trans PF03547.13 ETO19689.1 - 0.23 9.7 1.5 0.34 9.1 1.0 1.4 1 0 0 1 1 1 0 Membrane transport protein Vps52 PF04129.7 ETO19690.1 - 4.6e-22 78.2 1.7 4.7e-22 78.1 0.3 1.7 2 0 0 2 2 2 1 Vps52 / Sac2 family Hormone_1 PF00103.15 ETO19690.1 - 0.013 14.8 2.6 0.014 14.7 0.8 1.6 1 1 0 1 1 1 0 Somatotropin hormone family Vps52 PF04129.7 ETO19691.1 - 7.4e-23 80.8 9.9 8.7e-23 80.6 6.8 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family DUF2648 PF10855.3 ETO19691.1 - 0.016 14.6 0.1 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) zf-TRAF PF02176.13 ETO19692.1 - 0.00016 22.0 3.0 0.00016 22.0 2.1 2.4 2 0 0 2 2 2 1 TRAF-type zinc finger zf-H2C2_5 PF13909.1 ETO19692.1 - 0.094 12.9 3.0 7.1 7.0 0.0 3.2 2 1 0 2 2 2 0 C2H2-type zinc-finger domain WD40 PF00400.27 ETO19693.1 - 6.4e-26 89.2 12.3 4e-10 39.1 1.4 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO19693.1 - 0.00052 18.2 0.3 0.00092 17.4 0.2 1.5 1 1 0 1 1 1 1 Nucleoporin Nup120/160 DUF3595 PF12166.3 ETO19694.1 - 9.1e-65 219.1 5.9 7.1e-39 133.8 0.1 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3595) SR-25 PF10500.4 ETO19695.1 - 0.96 8.8 14.3 0.22 10.9 3.9 2.6 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Ret_tiss PF10044.4 ETO19696.1 - 2 9.0 6.3 14 6.2 0.0 3.9 4 1 0 4 4 4 0 Retinal tissue protein PH_3 PF14593.1 ETO19697.1 - 6.7e-09 35.5 0.1 1e-08 34.9 0.1 1.2 1 0 0 1 1 1 1 PH domain PH PF00169.24 ETO19697.1 - 3.4e-07 30.4 0.3 5e-07 29.8 0.2 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 ETO19697.1 - 7.2e-07 29.4 2.1 3.1e-06 27.4 1.4 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 ETO19697.1 - 2.3e-06 27.5 0.2 3.3e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain Myosin_TH1 PF06017.8 ETO19697.1 - 0.0031 16.8 0.0 0.004 16.4 0.0 1.1 1 0 0 1 1 1 1 Myosin tail Vps53_N PF04100.7 ETO19698.1 - 3e-05 22.9 0.0 6.3e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Vps53-like, N-terminal RAI1 PF08652.6 ETO19699.1 - 0.011 15.4 0.0 0.04 13.7 0.0 1.9 1 0 0 1 1 1 0 RAI1 like PD-(D/E)XK nuclease EBV-NA3 PF05009.7 ETO19700.1 - 0.14 11.3 1.7 0.2 10.8 1.2 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Dynamin_N PF00350.18 ETO19701.1 - 4.9e-17 62.2 1.0 6.7e-08 32.5 0.3 2.9 1 1 1 2 2 2 2 Dynamin family MMR_HSR1 PF01926.18 ETO19701.1 - 9.2e-15 54.6 0.2 3e-14 52.9 0.2 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 ETO19701.1 - 2.9e-06 26.8 1.3 1.5e-05 24.4 0.9 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 ETO19701.1 - 3.6e-05 23.0 0.9 6e-05 22.2 0.1 1.7 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 ETO19701.1 - 3.9e-05 22.9 1.6 0.15 11.3 0.1 2.5 1 1 1 2 2 2 2 Ferrous iron transport protein B IIGP PF05049.8 ETO19701.1 - 5.8e-05 22.0 1.4 0.0028 16.5 0.7 2.5 2 1 0 2 2 2 1 Interferon-inducible GTPase (IIGP) Miro PF08477.8 ETO19701.1 - 0.0001 22.7 0.6 0.0013 19.1 0.4 2.4 1 1 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 ETO19701.1 - 0.0031 16.7 0.0 0.019 14.1 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 cobW PF02492.14 ETO19701.1 - 0.011 15.1 1.3 0.011 15.1 0.9 2.1 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MCM_N PF14551.1 ETO19702.1 - 0.00041 20.8 0.0 0.00094 19.6 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain MCM_N PF14551.1 ETO19703.1 - 0.0002 21.8 1.4 0.0002 21.8 0.9 1.6 2 0 0 2 2 2 1 MCM N-terminal domain Neisseria_TspB PF05616.8 ETO19704.1 - 0.69 8.2 6.7 0.89 7.8 4.6 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Hid1 PF12722.2 ETO19704.1 - 0.71 7.4 8.5 0.86 7.1 5.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Hex_IIIa PF02455.11 ETO19704.1 - 1.1 7.9 8.6 0.73 8.4 5.0 1.3 1 1 0 1 1 1 0 Hexon-associated protein (IIIa) Cyclin_N PF00134.18 ETO19707.1 - 3.8e-34 116.9 1.5 2.4e-33 114.3 1.0 2.0 1 1 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 ETO19707.1 - 2.9e-11 43.3 1.4 8.6e-11 41.8 0.1 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain BRCT_assoc PF12820.2 ETO19707.1 - 0.025 14.3 0.8 0.025 14.3 0.5 1.4 2 0 0 2 2 2 0 Serine-rich domain associated with BRCT DUF1408 PF07193.6 ETO19707.1 - 0.3 10.6 1.6 4.2 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1408) DUF4339 PF14237.1 ETO19708.1 - 0.00019 20.9 0.1 0.00039 19.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4339) SOBP PF15279.1 ETO19708.1 - 3.8 7.8 10.0 4.7 7.5 6.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Mem_trans PF03547.13 ETO19708.1 - 9.8 4.3 6.4 12 4.1 4.4 1.1 1 0 0 1 1 1 0 Membrane transport protein Exo_endo_phos PF03372.18 ETO19709.1 - 3.9e-06 27.0 0.0 5.2e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RNase_H2_suC PF08615.6 ETO19709.1 - 0.11 12.2 0.1 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) RNA_polI_A34 PF08208.6 ETO19709.1 - 7.3 6.1 10.7 25 4.4 0.0 2.7 2 1 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Exo_endo_phos PF03372.18 ETO19710.1 - 6.8e-08 32.7 0.1 1.1e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family C2 PF00168.25 ETO19710.1 - 1.3e-06 28.1 0.0 3.2e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 C2 domain Endonuclease_5 PF04493.9 ETO19711.1 - 1.4e-13 50.7 0.0 2.6e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Endonuclease V DUF674 PF05056.7 ETO19712.1 - 0.048 12.2 0.8 0.062 11.9 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF674) Trypan_PARP PF05887.6 ETO19712.1 - 0.28 10.9 5.5 0.53 10.0 3.8 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RasGAP PF00616.14 ETO19713.1 - 0.00026 20.7 0.3 0.00037 20.2 0.2 1.4 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase Picorna_P3A PF06363.6 ETO19714.1 - 1.3 9.1 5.1 0.58 10.1 1.0 2.3 3 0 0 3 3 3 0 Picornaviridae P3A protein RasGEF PF00617.14 ETO19716.1 - 3.6e-30 105.0 3.4 4.9e-24 85.0 0.2 2.8 3 0 0 3 3 3 2 RasGEF domain RasGEF_N PF00618.15 ETO19716.1 - 4.7e-06 26.6 2.9 4.7e-06 26.6 2.0 2.1 2 0 0 2 2 2 1 RasGEF N-terminal motif Inhibitor_I71 PF12628.2 ETO19716.1 - 0.026 14.1 0.8 0.026 14.1 0.6 2.0 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor Packaging_FI PF14000.1 ETO19716.1 - 5.9 7.1 6.8 13 6.0 0.9 2.5 2 1 0 2 2 2 0 DNA packaging protein FI USP8_dimer PF08969.6 ETO19716.1 - 9.3 6.2 10.9 2.5 8.0 1.6 3.0 3 0 0 3 3 3 0 USP8 dimerisation domain Prolamin_like PF05617.6 ETO19718.1 - 0.073 13.2 1.4 0.14 12.3 1.0 1.5 1 0 0 1 1 1 0 Prolamin-like DUF3540 PF12059.3 ETO19718.1 - 0.12 11.9 4.3 0.17 11.5 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3540) Lebercilin PF15619.1 ETO19720.1 - 0.00029 20.3 9.8 0.00037 19.9 6.8 1.2 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease GET2 PF08690.5 ETO19720.1 - 0.0018 17.5 2.8 0.0022 17.3 1.9 1.1 1 0 0 1 1 1 1 GET complex subunit GET2 DivIC PF04977.10 ETO19720.1 - 0.0058 16.0 5.8 0.012 15.0 4.0 1.6 1 0 0 1 1 1 1 Septum formation initiator EMP24_GP25L PF01105.19 ETO19720.1 - 0.0059 16.3 0.4 0.0067 16.1 0.3 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Synaptobrevin PF00957.16 ETO19720.1 - 0.0073 15.8 3.2 0.011 15.2 2.2 1.2 1 0 0 1 1 1 1 Synaptobrevin Atg14 PF10186.4 ETO19720.1 - 0.011 14.7 8.8 0.012 14.5 6.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DivIVA PF05103.8 ETO19720.1 - 0.025 14.6 8.8 0.045 13.8 6.1 1.4 1 0 0 1 1 1 0 DivIVA protein Fmp27_WPPW PF10359.4 ETO19720.1 - 0.03 12.7 5.8 0.032 12.6 4.0 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain HXXSHH PF07586.6 ETO19720.1 - 0.04 12.8 0.6 0.049 12.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Vmethyltransf_C PF08456.5 ETO19720.1 - 0.055 12.8 1.3 0.081 12.3 0.9 1.2 1 0 0 1 1 1 0 Viral methyltransferase C-terminal DUF4407 PF14362.1 ETO19720.1 - 0.058 12.3 4.4 0.071 12.0 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fungal_trans_2 PF11951.3 ETO19720.1 - 0.061 11.9 0.7 0.079 11.5 0.5 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF607 PF04678.8 ETO19720.1 - 0.086 12.7 0.4 0.099 12.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF607 DUF342 PF03961.8 ETO19720.1 - 0.088 11.2 4.9 0.094 11.1 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) UPF0118 PF01594.11 ETO19720.1 - 0.1 11.5 0.2 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF20 Med9 PF07544.8 ETO19720.1 - 0.1 12.3 5.1 0.2 11.3 3.6 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF1664 PF07889.7 ETO19720.1 - 0.11 12.3 1.4 0.16 11.8 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4337 PF14235.1 ETO19720.1 - 0.11 12.3 1.5 0.17 11.6 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Bap31 PF05529.7 ETO19720.1 - 0.17 11.3 12.1 0.031 13.7 3.9 2.2 1 1 0 2 2 2 0 B-cell receptor-associated protein 31-like V_ATPase_I PF01496.14 ETO19720.1 - 0.21 9.4 6.8 0.23 9.2 4.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TSC22 PF01166.13 ETO19720.1 - 0.36 10.8 5.1 0.23 11.4 1.9 2.0 1 1 1 2 2 2 0 TSC-22/dip/bun family AATF-Che1 PF13339.1 ETO19720.1 - 0.67 10.1 10.8 0.33 11.0 5.9 1.6 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Voldacs PF03517.8 ETO19720.1 - 2 8.2 6.8 1.4 8.7 3.4 1.7 1 1 0 1 1 1 0 Regulator of volume decrease after cellular swelling DUF912 PF06024.7 ETO19720.1 - 4.4 7.4 6.2 15 5.7 4.3 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Daxx PF03344.10 ETO19721.1 - 0.00013 20.6 13.8 0.00013 20.6 9.6 1.0 1 0 0 1 1 1 1 Daxx Family Utp14 PF04615.8 ETO19721.1 - 0.00042 18.6 2.4 0.00042 18.6 1.7 2.0 1 1 1 2 2 1 1 Utp14 protein Tim54 PF11711.3 ETO19721.1 - 0.048 12.2 1.1 0.055 12.0 0.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SAPS PF04499.10 ETO19721.1 - 0.17 10.4 5.6 0.16 10.6 3.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Spore_coat_CotO PF14153.1 ETO19721.1 - 0.33 10.3 5.5 0.43 10.0 3.8 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Afi1 PF07792.7 ETO19721.1 - 0.44 10.5 9.8 0.64 10.0 6.8 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CDC45 PF02724.9 ETO19721.1 - 0.9 7.4 20.6 1 7.3 14.3 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 ETO19721.1 - 1.2 8.6 20.9 1.8 8.1 14.5 1.3 1 0 0 1 1 1 0 YL1 nuclear protein SPX PF03105.14 ETO19721.1 - 1.6 8.4 13.8 1.9 8.2 9.6 1.1 1 0 0 1 1 1 0 SPX domain Nop14 PF04147.7 ETO19721.1 - 2.4 5.9 31.6 2.7 5.7 21.9 1.0 1 0 0 1 1 1 0 Nop14-like family Spb1_C PF07780.7 ETO19721.1 - 4.3 6.7 12.6 6.6 6.1 8.7 1.3 1 0 0 1 1 1 0 Spb1 C-terminal domain Raftlin PF15250.1 ETO19721.1 - 9.1 4.6 6.8 11 4.3 4.7 1.0 1 0 0 1 1 1 0 Raftlin DUF1777 PF08648.7 ETO19722.1 - 0.042 13.5 16.0 0.045 13.4 11.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Trypan_PARP PF05887.6 ETO19722.1 - 0.24 11.2 6.6 0.27 11.0 4.5 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Atrophin-1 PF03154.10 ETO19722.1 - 0.44 8.6 15.7 0.45 8.6 10.9 1.1 1 0 0 1 1 1 0 Atrophin-1 family MIP-T3 PF10243.4 ETO19722.1 - 0.65 8.3 27.8 0.69 8.3 19.3 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1509 PF07420.6 ETO19722.1 - 0.83 8.8 8.4 1 8.5 5.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Myc_N PF01056.13 ETO19722.1 - 0.83 8.7 11.4 0.89 8.6 7.9 1.0 1 0 0 1 1 1 0 Myc amino-terminal region DUF4612 PF15389.1 ETO19722.1 - 1.5 9.4 16.0 1.6 9.3 11.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4612) U79_P34 PF03064.11 ETO19722.1 - 3 7.2 17.4 3.1 7.2 12.0 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF1510 PF07423.6 ETO19722.1 - 6.3 6.1 22.5 6.6 6.0 15.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FAM60A PF15396.1 ETO19722.1 - 7 6.3 15.8 7.7 6.1 10.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A RabGAP-TBC PF00566.13 ETO19722.1 - 9.5 5.6 8.8 11 5.4 6.1 1.1 1 0 0 1 1 1 0 Rab-GTPase-TBC domain Glyco_hydro_3 PF00933.16 ETO19723.1 - 1.3e-27 96.5 0.0 2.1e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETO19723.1 - 1.9e-15 56.9 0.0 2.9e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Beta_helix PF13229.1 ETO19724.1 - 0.00025 20.8 8.9 0.14 11.8 2.9 2.4 1 1 1 2 2 2 2 Right handed beta helix region Mucin PF01456.12 ETO19724.1 - 0.00062 19.5 10.0 0.00075 19.2 6.9 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein MGC-24 PF05283.6 ETO19724.1 - 0.0031 17.3 8.1 0.0046 16.7 5.6 1.4 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24) Chlam_PMP PF02415.12 ETO19724.1 - 0.015 15.4 20.8 0.79 10.1 0.8 6.1 6 1 0 6 6 6 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Pec_lyase_C PF00544.14 ETO19724.1 - 0.048 13.1 1.5 0.12 11.8 0.3 1.9 2 0 0 2 2 2 0 Pectate lyase Dicty_REP PF05086.7 ETO19724.1 - 0.34 8.6 2.8 0.39 8.4 1.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Gly-zipper_OmpA PF13436.1 ETO19726.1 - 0.0026 17.4 6.5 0.0026 17.4 4.5 2.1 2 1 0 2 2 2 1 Glycine-zipper containing OmpA-like membrane domain Hid1 PF12722.2 ETO19726.1 - 0.21 9.2 22.8 0.29 8.7 15.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Laminin_II PF06009.7 ETO19727.1 - 0.0064 16.2 3.9 0.0097 15.6 2.7 1.2 1 0 0 1 1 1 1 Laminin Domain II FbpA PF05833.6 ETO19727.1 - 0.017 13.6 4.7 0.03 12.8 3.3 1.4 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) PIP49_C PF12260.3 ETO19727.1 - 0.059 12.7 1.2 0.14 11.5 0.0 1.9 1 1 0 2 2 2 0 Protein-kinase domain of FAM69 Uds1 PF15456.1 ETO19727.1 - 0.23 11.4 3.4 0.37 10.7 2.3 1.3 1 0 0 1 1 1 0 Up-regulated During Septation IncA PF04156.9 ETO19727.1 - 0.33 10.5 4.9 0.45 10.0 3.4 1.3 1 0 0 1 1 1 0 IncA protein Snapin_Pallidin PF14712.1 ETO19727.1 - 5.1 7.4 8.6 1.4 9.2 3.8 1.7 2 0 0 2 2 2 0 Snapin/Pallidin CreD PF06123.7 ETO19728.1 - 0.071 11.6 1.6 0.11 10.9 1.1 1.3 1 0 0 1 1 1 0 Inner membrane protein CreD GLYCAM-1 PF05242.6 ETO19728.1 - 0.093 12.6 7.1 0.17 11.7 4.9 1.4 1 0 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) DIRP PF06584.8 ETO19728.1 - 0.16 11.8 0.8 0.66 9.8 0.1 2.2 1 1 2 3 3 3 0 DIRP DUF4414 PF14377.1 ETO19728.1 - 9.2 6.2 9.2 2.9 7.8 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4414) Ly49 PF08391.5 ETO19729.1 - 0.02 15.0 1.0 0.025 14.6 0.7 1.1 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region AIG1 PF04548.11 ETO19729.1 - 0.043 12.9 1.4 0.053 12.6 1.0 1.1 1 0 0 1 1 1 0 AIG1 family Glyco_transf_92 PF01697.22 ETO19730.1 - 2e-05 24.0 7.2 2e-05 24.0 5.0 2.9 2 1 0 2 2 2 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.1 ETO19730.1 - 0.0061 16.8 2.4 0.0061 16.8 1.7 2.2 3 1 0 3 3 3 1 Glycosyl transferase family 2 PDZ PF00595.19 ETO19731.1 - 0.0029 17.7 0.0 0.0071 16.5 0.0 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) DUF2796 PF10986.3 ETO19731.1 - 0.0096 15.9 3.0 0.0096 15.9 2.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2796) PDZ_2 PF13180.1 ETO19731.1 - 0.018 14.9 0.0 0.057 13.3 0.0 1.8 1 0 0 1 1 1 0 PDZ domain DUF3394 PF11874.3 ETO19731.1 - 0.047 13.2 0.0 0.094 12.2 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3394) Cellulose_synt PF03552.9 ETO19731.1 - 4.1 5.5 8.2 0.38 9.0 2.0 1.8 1 1 0 2 2 2 0 Cellulose synthase RNase_T PF00929.19 ETO19733.1 - 1.8e-09 38.1 1.8 1.3e-08 35.3 0.1 2.4 2 1 1 3 3 3 1 Exonuclease DNA_pol_A_exo1 PF01612.15 ETO19733.1 - 0.036 13.5 1.0 0.1 12.0 0.1 2.0 2 0 0 2 2 2 0 3'-5' exonuclease TPP_enzyme_C PF02775.16 ETO19734.1 - 5.5e-23 81.2 0.0 1.3e-22 80.0 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.13 ETO19734.1 - 1.7e-15 56.9 0.1 7.2e-15 54.8 0.1 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 ETO19734.1 - 1.8e-13 50.4 0.0 4.2e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain AAR2 PF05282.6 ETO19734.1 - 0.0021 17.0 3.0 0.0041 16.1 2.1 1.4 1 0 0 1 1 1 1 AAR2 protein CO_dh PF02552.11 ETO19734.1 - 0.027 14.0 2.0 0.033 13.7 0.1 2.1 2 1 0 2 2 2 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit zf-TRAF PF02176.13 ETO19735.1 - 0.0001 22.5 1.6 0.0001 22.5 1.1 2.4 2 0 0 2 2 2 1 TRAF-type zinc finger RNB PF00773.14 ETO19735.1 - 0.011 15.0 0.1 0.011 15.0 0.0 2.1 1 1 1 2 2 2 0 RNB domain Ovate PF04844.8 ETO19735.1 - 0.016 14.9 0.8 0.078 12.7 0.0 2.6 3 0 0 3 3 3 0 Transcriptional repressor, ovate DUF342 PF03961.8 ETO19735.1 - 0.73 8.1 18.5 1 7.6 12.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF972 PF06156.8 ETO19735.1 - 2.6 8.4 26.8 2.8 8.3 3.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) zf-C3HC4_2 PF13923.1 ETO19735.1 - 5.3 7.1 11.6 0.87 9.6 1.5 3.5 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RCR PF12273.3 ETO19737.1 - 0.0046 17.5 0.2 0.0046 17.5 0.1 1.8 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red Vac7 PF12751.2 ETO19739.1 - 0.11 11.3 0.6 0.11 11.3 0.4 1.0 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 YcxB PF14317.1 ETO19739.1 - 0.22 10.8 2.3 1.8 7.8 1.2 2.1 1 1 0 1 1 1 0 YcxB-like protein Spore_coat_CotO PF14153.1 ETO19740.1 - 1 8.7 9.3 1.8 7.9 6.5 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Prothymosin PF03247.9 ETO19740.1 - 4.6 7.4 20.9 1.2 9.3 10.2 2.1 2 0 0 2 2 2 0 Prothymosin/parathymosin family FYDLN_acid PF09538.5 ETO19740.1 - 6.3 7.4 12.8 6 7.4 6.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) ANAPC15 PF15243.1 ETO19740.1 - 8.9 6.4 14.8 1.6 8.8 7.3 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 zf-HC5HC2H_2 PF13832.1 ETO19741.1 - 2.9e-14 53.0 27.2 1.1e-07 31.8 2.4 4.4 4 0 0 4 4 4 3 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 ETO19741.1 - 2.4e-08 34.0 4.8 2.4e-08 34.0 3.3 4.7 4 1 1 5 5 5 2 PHD-like zinc-binding domain PHD_2 PF13831.1 ETO19741.1 - 0.00015 21.0 12.0 0.00015 21.0 8.3 3.3 4 0 0 4 4 4 1 PHD-finger PHD PF00628.24 ETO19741.1 - 0.00063 19.3 14.2 0.00063 19.3 9.8 4.3 5 0 0 5 5 5 2 PHD-finger Voldacs PF03517.8 ETO19741.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling Cytochrome_CBB3 PF13442.1 ETO19742.1 - 0.021 14.9 0.1 0.035 14.2 0.1 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III RCC1 PF00415.13 ETO19743.1 - 8.6e-24 83.5 2.7 1.3e-09 38.0 0.7 3.6 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO19743.1 - 7e-14 51.0 9.6 5.6e-07 29.0 0.7 2.5 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat Nucleotid_trans PF03407.11 ETO19745.1 - 2.7e-16 59.9 0.1 6.5e-16 58.7 0.0 1.6 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase Shisa PF13908.1 ETO19746.1 - 0.011 15.9 0.7 0.013 15.6 0.5 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF1049 PF06305.6 ETO19746.1 - 0.014 14.9 0.1 0.036 13.5 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1049) DUF2681 PF10883.3 ETO19746.1 - 0.017 15.3 0.8 0.017 15.3 0.6 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) Sulfate_transp PF00916.15 ETO19746.1 - 0.037 13.0 0.6 0.043 12.8 0.4 1.1 1 0 0 1 1 1 0 Sulfate transporter family DUF2208 PF09973.4 ETO19746.1 - 0.041 13.1 5.5 0.07 12.3 3.8 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2208) Sas10_Utp3 PF04000.10 ETO19746.1 - 6.5 7.0 7.0 19 5.5 2.8 2.6 2 1 0 2 2 2 0 Sas10/Utp3/C1D family CDC45 PF02724.9 ETO19747.1 - 2.1 6.2 5.6 2.3 6.1 3.9 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.7 ETO19747.1 - 4.7 6.2 12.1 5.7 5.9 8.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 ETO19747.1 - 4.9 4.9 12.8 6.9 4.4 8.9 1.2 1 0 0 1 1 1 0 Nop14-like family MCM_N PF14551.1 ETO19748.1 - 0.0073 16.7 1.7 0.0091 16.4 0.3 1.7 2 0 0 2 2 2 1 MCM N-terminal domain VPS9 PF02204.13 ETO19750.1 - 3.9e-13 49.3 0.6 2.5e-11 43.5 0.0 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain CAP_GLY PF01302.20 ETO19750.1 - 3.8e-12 45.7 0.4 6.7e-12 44.9 0.3 1.3 1 0 0 1 1 1 1 CAP-Gly domain DUF3145 PF11343.3 ETO19750.1 - 0.068 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3145) DUF4168 PF13767.1 ETO19750.1 - 0.13 12.9 4.4 0.17 12.5 0.2 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4168) EF-hand_8 PF13833.1 ETO19751.1 - 0.0014 18.2 2.5 0.35 10.5 0.7 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO19751.1 - 0.0019 17.9 1.1 0.61 10.1 0.5 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 ETO19751.1 - 0.0032 16.6 1.8 0.12 11.6 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 ETO19751.1 - 0.008 16.2 4.7 0.25 11.5 2.8 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 ETO19751.1 - 0.018 14.3 0.1 0.23 10.8 0.0 2.4 2 0 0 2 2 2 0 EF hand RB_B PF01857.15 ETO19751.1 - 0.036 13.5 0.3 0.059 12.8 0.2 1.3 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain EF-hand_4 PF12763.2 ETO19751.1 - 0.28 10.9 3.4 0.29 10.8 1.1 1.9 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand MT PF12777.2 ETO19752.1 - 2.3e-23 82.4 11.1 3.4e-23 81.9 7.7 1.2 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 ETO19752.1 - 6.2e-14 51.3 0.4 2.9e-13 49.1 0.0 2.2 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 Apc5 PF12862.2 ETO19752.1 - 0.092 12.5 1.9 0.36 10.6 0.1 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 WEMBL PF05701.6 ETO19752.1 - 0.34 9.3 31.5 0.16 10.3 5.3 2.2 2 0 0 2 2 2 0 Weak chloroplast movement under blue light DUF2203 PF09969.4 ETO19752.1 - 0.62 10.3 15.2 4.5 7.5 1.0 3.6 2 2 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) ERM PF00769.14 ETO19752.1 - 1.1 8.7 23.5 0.81 9.1 1.3 2.3 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Reo_sigmaC PF04582.7 ETO19752.1 - 1.1 8.3 9.5 0.31 10.1 0.8 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Spc7 PF08317.6 ETO19752.1 - 1.2 7.7 28.6 0.053 12.1 4.8 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF2968 PF11180.3 ETO19752.1 - 1.2 8.4 21.9 3.1 7.1 1.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Filament PF00038.16 ETO19752.1 - 1.4 8.3 24.8 1.2 8.5 2.7 2.4 2 0 0 2 2 2 0 Intermediate filament protein L31 PF09784.4 ETO19752.1 - 2 8.5 10.5 0.3 11.1 1.9 3.0 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L31 DUF745 PF05335.8 ETO19752.1 - 4.1 6.8 20.9 1.7 8.0 2.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Laminin_II PF06009.7 ETO19752.1 - 4.2 7.1 27.5 0.054 13.2 2.9 3.0 3 0 0 3 3 3 0 Laminin Domain II IncA PF04156.9 ETO19752.1 - 5.4 6.5 32.7 0.055 13.0 6.9 2.5 2 0 0 2 2 2 0 IncA protein AAA_13 PF13166.1 ETO19752.1 - 8.2 4.7 29.8 0.16 10.3 6.3 2.3 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.2 ETO19754.1 - 7.1e-14 51.5 2.5 7.7e-14 51.4 1.8 1.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 ETO19754.1 - 0.0048 17.0 0.1 0.017 15.2 0.0 1.9 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 ETO19754.1 - 0.0065 15.9 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.1 ETO19754.1 - 0.014 15.4 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 ETO19754.1 - 0.043 13.5 0.0 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) T2SE PF00437.15 ETO19754.1 - 0.14 11.0 0.1 1.7 7.4 0.0 2.4 2 2 0 2 2 2 0 Type II/IV secretion system protein G-alpha PF00503.15 ETO19757.1 - 1.8e-55 188.2 5.3 2.1e-55 188.0 3.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO19757.1 - 1e-09 37.9 0.2 2e-09 36.9 0.1 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family EMP24_GP25L PF01105.19 ETO19759.1 - 0.013 15.2 6.6 0.056 13.1 0.1 2.6 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF3782 PF12644.2 ETO19759.1 - 0.089 12.5 1.9 1.5 8.7 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3782) UPF0184 PF03670.8 ETO19759.1 - 0.23 11.6 2.4 13 5.9 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Tantalus PF15386.1 ETO19759.1 - 1.7 8.4 5.2 2.8 7.7 0.1 3.2 3 0 0 3 3 3 0 Drosophila Tantalus-like Adeno_PIX PF03955.9 ETO19759.1 - 3.9 8.0 5.9 59 4.2 1.6 2.9 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) DUF1285 PF06938.6 ETO19760.1 - 0.13 12.2 1.5 1.6 8.7 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1285) CLPTM1 PF05602.7 ETO19760.1 - 0.18 10.4 8.1 0.21 10.2 5.6 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) SID-1_RNA_chan PF13965.1 ETO19760.1 - 3.2 5.8 6.8 2.8 6.0 4.2 1.3 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 NAC PF01849.13 ETO19762.1 - 2.7e-17 62.0 0.2 2.7e-17 62.0 0.2 2.6 3 0 0 3 3 3 1 NAC domain HI0933_like PF03486.9 ETO19762.1 - 0.087 11.2 2.9 0.072 11.5 0.7 1.7 1 1 1 2 2 2 0 HI0933-like protein zf-RanBP PF00641.13 ETO19764.1 - 3.3e-06 26.0 11.2 0.0047 15.9 1.1 3.2 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others CAP_GLY PF01302.20 ETO19765.1 - 1.2e-25 89.0 5.8 5e-13 48.5 0.1 2.7 2 0 0 2 2 2 2 CAP-Gly domain DUF3850 PF12961.2 ETO19765.1 - 0.067 13.1 0.5 0.96 9.4 0.1 2.5 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3850) DUF2577 PF10844.3 ETO19765.1 - 0.99 9.4 5.1 0.56 10.2 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2577) Bac_small_YrzI PF09501.5 ETO19766.1 - 0.65 9.9 3.2 0.91 9.4 0.5 2.2 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) ubiquitin PF00240.18 ETO19767.1 - 9.6e-07 28.1 0.0 9.6e-07 28.1 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 ETO19767.1 - 0.001 18.7 3.4 0.0019 17.8 0.0 2.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Suf PF05843.9 ETO19767.1 - 0.0023 17.6 0.3 0.0027 17.4 0.2 1.2 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) DUF912 PF06024.7 ETO19767.1 - 0.026 14.5 0.2 0.026 14.5 0.1 3.3 3 1 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) NUC194 PF08163.7 ETO19767.1 - 0.035 12.9 1.4 0.047 12.5 1.0 1.1 1 0 0 1 1 1 0 NUC194 domain BAF1_ABF1 PF04684.8 ETO19767.1 - 0.13 11.0 15.2 0.16 10.8 10.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor FKBP_N PF01346.13 ETO19767.1 - 0.29 11.1 13.4 0.47 10.5 9.3 1.2 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Rtf2 PF04641.7 ETO19767.1 - 0.52 9.4 7.9 0.67 9.0 5.5 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger NPR3 PF03666.8 ETO19767.1 - 0.61 8.5 6.1 0.8 8.1 4.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 BLVR PF06375.6 ETO19767.1 - 1.5 8.6 11.5 0.28 11.0 1.5 2.1 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) UFD1 PF03152.9 ETO19768.1 - 1.1e-17 63.7 0.0 6.1e-08 31.9 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 ATP-synt_8 PF00895.15 ETO19770.1 - 0.1 12.8 1.0 0.27 11.4 0.7 1.7 1 0 0 1 1 1 0 ATP synthase protein 8 DUF2356 PF10189.4 ETO19772.1 - 0.0011 18.1 0.5 0.0012 17.9 0.3 1.1 1 0 0 1 1 1 1 Conserved protein (DUF2356) Pkinase PF00069.20 ETO19772.1 - 0.0019 17.3 0.0 0.0023 17.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 ETO19773.1 - 7.9e-32 110.4 0.1 1.1e-31 109.9 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO19773.1 - 5.1e-08 32.3 0.1 7.4e-08 31.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETO19773.1 - 0.00024 20.9 0.0 0.00039 20.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 ETO19773.1 - 0.0063 15.5 0.1 0.011 14.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 ETO19773.1 - 0.049 12.9 0.1 0.083 12.2 0.1 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL zf-C3HC4_2 PF13923.1 ETO19776.1 - 0.012 15.6 14.7 0.03 14.3 10.2 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO19776.1 - 0.17 11.5 11.8 0.41 10.3 8.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO19776.1 - 0.87 9.4 14.7 2.1 8.2 10.2 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 ETO19776.1 - 1.1 9.0 12.8 2.7 7.8 8.8 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Nop14 PF04147.7 ETO19776.1 - 1.6 6.5 11.9 3.3 5.5 8.2 1.5 1 0 0 1 1 1 0 Nop14-like family DUF3439 PF11921.3 ETO19778.1 - 0.077 12.7 4.1 0.14 11.9 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SRP19 PF01922.12 ETO19779.1 - 4.7e-05 23.8 1.2 0.00029 21.3 0.0 2.1 2 0 0 2 2 2 1 SRP19 protein RNA_pol_Rpc4 PF05132.9 ETO19779.1 - 0.11 12.4 4.0 0.15 12.0 2.8 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.7 ETO19779.1 - 0.12 12.2 4.8 0.13 12.1 3.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Asp-B-Hydro_N PF05279.6 ETO19779.1 - 0.22 11.3 6.5 0.27 11.0 4.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region RNase_H2-Ydr279 PF09468.5 ETO19779.1 - 0.34 10.0 7.6 0.38 9.8 5.2 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF2149 PF09919.4 ETO19779.1 - 0.63 10.1 3.5 0.93 9.6 2.4 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) YqfQ PF14181.1 ETO19779.1 - 0.98 9.4 9.5 1.3 9.0 6.6 1.1 1 0 0 1 1 1 0 YqfQ-like protein DUF2570 PF10828.3 ETO19779.1 - 1.1 8.9 9.0 1.4 8.5 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Ax_dynein_light PF10211.4 ETO19779.1 - 1.3 8.8 12.1 1.6 8.5 8.4 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain Sec62 PF03839.11 ETO19779.1 - 9.4 5.5 10.8 11 5.3 7.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Peptidase_S49_N PF08496.5 ETO19779.1 - 9.7 5.9 9.8 12 5.6 6.8 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DEP PF00610.16 ETO19780.1 - 1.6e-38 130.3 0.3 1.5e-18 66.3 0.0 2.3 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) GSHPx PF00255.14 ETO19781.1 - 1.9e-36 123.6 0.1 4.1e-36 122.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.5 ETO19781.1 - 0.0021 17.5 0.1 0.0035 16.8 0.0 1.4 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.9 ETO19781.1 - 0.011 15.3 0.1 0.042 13.4 0.1 1.9 2 0 0 2 2 2 0 SCO1/SenC DUF1088 PF06469.6 ETO19781.1 - 0.048 13.0 0.7 0.095 12.1 0.5 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1088) FliJ PF02050.11 ETO19783.1 - 0.21 11.6 9.9 0.57 10.2 6.9 1.7 1 0 0 1 1 1 0 Flagellar FliJ protein IncA PF04156.9 ETO19783.1 - 0.75 9.3 9.7 1.6 8.2 6.7 1.5 1 0 0 1 1 1 0 IncA protein Vert_HS_TF PF06546.6 ETO19786.1 - 0.0018 17.7 0.5 0.0032 16.8 0.4 1.3 1 0 0 1 1 1 1 Vertebrate heat shock transcription factor Gcd10p PF04189.8 ETO19786.1 - 0.011 14.8 6.3 0.023 13.8 4.3 1.5 1 0 0 1 1 1 0 Gcd10p family DUF2722 PF10846.3 ETO19786.1 - 0.93 8.4 6.7 1.5 7.7 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TLP-20 PF06088.6 ETO19786.1 - 3.9 7.1 13.1 1.2 8.8 7.0 1.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PUB PF09409.5 ETO19788.1 - 0.00017 21.3 0.3 0.00049 19.8 0.2 2.0 1 1 0 1 1 1 1 PUB domain DHQ_synthase PF01761.15 ETO19788.1 - 0.04 12.8 0.0 0.061 12.2 0.0 1.3 1 0 0 1 1 1 0 3-dehydroquinate synthase CW_binding_1 PF01473.15 ETO19788.1 - 0.57 10.4 9.0 7.2 6.9 1.6 2.7 2 0 0 2 2 2 0 Putative cell wall binding repeat PXA PF02194.10 ETO19789.1 - 2.4e-05 23.9 0.7 7.6e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 PXA domain MoaE PF02391.12 ETO19790.1 - 0.14 11.9 1.0 0.26 11.1 0.4 1.7 2 0 0 2 2 2 0 MoaE protein LAG1-DNAbind PF09271.6 ETO19790.1 - 0.21 12.0 4.4 0.54 10.7 3.1 1.8 1 1 0 1 1 1 0 LAG1, DNA binding Ofd1_CTDD PF10637.4 ETO19791.1 - 3e-13 49.5 0.8 4.6e-13 48.9 0.5 1.3 1 0 0 1 1 1 1 Oxoglutarate and iron-dependent oxygenase degradation C-term CompInhib_SCIN PF11546.3 ETO19791.1 - 0.0076 16.0 0.2 0.012 15.4 0.1 1.3 1 0 0 1 1 1 1 Staphylococcal complement inhibitor SCIN Asp PF00026.18 ETO19792.1 - 7.1e-20 71.4 0.1 8e-20 71.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp PF00026.18 ETO19793.1 - 6.6e-58 196.4 1.4 7.9e-58 196.1 1.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETO19793.1 - 8.2e-10 38.8 0.0 5.3e-09 36.2 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal 2OG-FeII_Oxy_3 PF13640.1 ETO19794.1 - 6.2e-18 65.1 0.0 7.6e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ofd1_CTDD PF10637.4 ETO19794.1 - 3.4e-07 29.6 0.0 3.9e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Oxoglutarate and iron-dependent oxygenase degradation C-term WD40 PF00400.27 ETO19795.1 - 2.4e-25 87.4 9.2 6.7e-09 35.3 0.1 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat DUF3977 PF13122.1 ETO19795.1 - 0.0016 18.2 0.7 0.16 11.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3977) eIF2A PF08662.6 ETO19795.1 - 0.023 14.4 0.2 1.1 8.9 0.0 3.0 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Me-amine-dh_H PF06433.6 ETO19795.1 - 0.041 12.5 0.0 0.23 10.0 0.0 2.0 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) Rav1p_C PF12234.3 ETO19795.1 - 0.11 10.6 0.0 0.17 9.9 0.0 1.2 1 0 0 1 1 1 0 RAVE protein 1 C terminal NHL PF01436.16 ETO19795.1 - 1.3 9.1 9.3 0.098 12.6 0.6 3.2 4 0 0 4 4 4 0 NHL repeat U-box PF04564.10 ETO19796.1 - 8.3e-09 35.2 0.2 5e-08 32.8 0.1 1.9 1 1 0 1 1 1 1 U-box domain DUF912 PF06024.7 ETO19797.1 - 0.074 13.1 9.5 0.026 14.5 3.5 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Secretin_N_2 PF07655.8 ETO19797.1 - 4.1 7.8 24.1 4.7 7.6 10.4 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain Menin PF05053.8 ETO19797.1 - 5.4 5.0 7.5 8.8 4.3 5.2 1.2 1 0 0 1 1 1 0 Menin Ion_trans PF00520.26 ETO19799.1 - 1.9e-08 33.8 42.8 4.7e-06 25.9 4.3 4.7 5 1 0 5 5 5 2 Ion transport protein EF-hand_1 PF00036.27 ETO19799.1 - 0.00083 18.4 0.2 0.19 11.1 0.0 3.0 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 ETO19799.1 - 0.0014 17.9 0.3 0.0095 15.2 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 ETO19799.1 - 0.012 15.4 0.3 2.9 8.0 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.1 ETO19799.1 - 0.098 12.8 2.7 0.39 10.8 0.5 2.7 2 1 1 3 3 3 0 EF-hand domain pair Peptidase_S49_N PF08496.5 ETO19799.1 - 1.6 8.5 11.8 0.12 12.1 0.9 2.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Occludin_ELL PF07303.8 ETO19800.1 - 0.27 11.9 6.7 0.64 10.7 4.7 1.6 1 0 0 1 1 1 0 Occludin homology domain Mnd1 PF03962.10 ETO19800.1 - 0.4 10.3 11.0 0.8 9.3 7.6 1.4 1 0 0 1 1 1 0 Mnd1 family Apc15p PF05841.6 ETO19801.1 - 0.69 10.6 21.2 2 9.1 0.7 2.3 2 0 0 2 2 2 0 Apc15p protein RCR PF12273.3 ETO19801.1 - 1.7 9.2 11.9 3.5 8.2 8.2 1.5 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red SR-25 PF10500.4 ETO19801.1 - 2.3 7.6 25.2 0.22 10.9 6.6 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Prenylcys_lyase PF07156.9 ETO19802.1 - 6.7e-40 137.1 2.2 1.1e-38 133.1 1.5 2.0 1 1 0 1 1 1 1 Prenylcysteine lyase Pyr_redox_2 PF07992.9 ETO19802.1 - 0.01 15.7 0.1 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETO19802.1 - 0.016 15.2 0.0 0.073 13.0 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 ETO19802.1 - 0.068 12.9 0.7 1.7 8.4 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding RCC1 PF00415.13 ETO19803.1 - 1.2e-05 25.4 7.0 8.8e-05 22.6 0.0 3.8 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO19803.1 - 9.2e-05 21.9 3.8 0.056 13.0 0.1 2.8 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat SecY PF00344.15 ETO19803.1 - 0.02 13.8 0.1 0.02 13.8 0.1 1.9 2 0 0 2 2 2 0 SecY translocase Mob1_phocein PF03637.12 ETO19805.1 - 0.00046 19.8 0.0 0.00063 19.4 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family Kelch_6 PF13964.1 ETO19806.1 - 0.00012 22.1 0.6 0.037 14.2 0.1 3.8 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO19806.1 - 0.0045 16.7 0.4 0.023 14.4 0.0 2.4 3 1 1 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO19806.1 - 0.087 12.3 2.9 0.17 11.4 0.2 2.7 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.1 ETO19806.1 - 0.096 12.6 1.8 5.4 7.0 0.1 3.2 3 0 0 3 3 3 0 Kelch motif Phytase-like PF13449.1 ETO19806.1 - 0.11 11.6 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Esterase-like activity of phytase Kelch_2 PF07646.10 ETO19806.1 - 0.13 12.0 0.3 0.93 9.3 0.0 2.6 1 1 1 2 2 2 0 Kelch motif Ead_Ea22 PF13935.1 ETO19807.1 - 0.0018 18.6 1.3 0.0033 17.7 0.9 1.6 1 1 0 1 1 1 1 Ead/Ea22-like protein DUF3829 PF12889.2 ETO19807.1 - 0.019 14.1 0.3 0.019 14.1 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) VPS9 PF02204.13 ETO19808.1 - 1.1e-08 35.0 0.1 6.4e-06 26.1 0.0 2.3 2 0 0 2 2 2 2 Vacuolar sorting protein 9 (VPS9) domain Methylase_S PF01420.14 ETO19808.1 - 0.036 14.0 0.1 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 Type I restriction modification DNA specificity domain DNA_gyraseB PF00204.20 ETO19808.1 - 0.098 11.8 0.1 0.18 11.0 0.1 1.4 1 0 0 1 1 1 0 DNA gyrase B IQ PF00612.22 ETO19808.1 - 0.14 11.9 0.2 0.24 11.1 0.2 1.4 1 0 0 1 1 1 0 IQ calmodulin-binding motif RGS PF00615.14 ETO19810.1 - 2e-05 24.6 0.0 4.4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain FLO_LFY PF01698.11 ETO19810.1 - 0.074 11.8 12.5 0.15 10.8 8.7 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein U79_P34 PF03064.11 ETO19810.1 - 0.42 10.0 13.7 0.65 9.4 9.5 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 eIF3_subunit PF08597.5 ETO19810.1 - 3.4 7.1 34.7 6.6 6.2 24.1 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Vfa1 PF08432.5 ETO19810.1 - 4 7.4 31.4 2.3 8.2 20.3 1.6 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1168 PF06658.7 ETO19810.1 - 7.3 6.1 31.0 0.23 10.9 16.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) DUF2956 PF11169.3 ETO19810.1 - 9.6 6.2 19.4 2.9 7.9 10.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) AF-4 PF05110.8 ETO19812.1 - 0.036 11.9 11.3 0.064 11.1 7.8 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Spt5_N PF11942.3 ETO19812.1 - 2.6 8.7 16.0 3.3 8.3 1.7 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal RXT2_N PF08595.6 ETO19812.1 - 4.5 7.0 9.8 1.1 9.0 1.9 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal PBP1_TM PF14812.1 ETO19812.1 - 5.5 7.3 19.2 1.2 9.4 3.3 2.8 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3245 PF11595.3 ETO19812.1 - 9.1 6.5 20.2 4.7 7.4 5.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Pkinase_Tyr PF07714.12 ETO19813.1 - 8.8e-13 47.9 0.3 8.8e-13 47.9 0.2 2.7 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 ETO19813.1 - 5e-08 32.4 0.0 5e-08 32.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain OKR_DC_1_C PF03711.10 ETO19813.1 - 0.99 9.4 4.2 5.5 7.0 0.9 2.5 2 1 0 2 2 2 0 Orn/Lys/Arg decarboxylase, C-terminal domain FCP1_C PF09309.5 ETO19813.1 - 2.6 7.2 6.3 4.1 6.6 4.4 1.4 1 0 0 1 1 1 0 FCP1, C-terminal MIP-T3 PF10243.4 ETO19814.1 - 2.6 6.3 51.4 3.4 6.0 35.6 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Tim54 PF11711.3 ETO19815.1 - 0.4 9.2 3.6 0.53 8.8 2.5 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 ZZ PF00569.12 ETO19818.1 - 2.9e-05 23.5 5.7 9.6e-05 21.8 3.9 1.9 1 0 0 1 1 1 1 Zinc finger, ZZ type CDC45 PF02724.9 ETO19819.1 - 0.02 12.9 15.2 0.03 12.3 10.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Cytomega_UL20A PF05984.7 ETO19819.1 - 0.098 12.8 2.7 0.23 11.6 1.9 1.6 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein Daxx PF03344.10 ETO19819.1 - 0.37 9.2 17.0 0.58 8.5 11.8 1.3 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 ETO19819.1 - 1.2 8.4 14.7 1.9 7.7 10.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RRN3 PF05327.6 ETO19819.1 - 2.2 6.2 8.9 2.9 5.9 6.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Tetraspannin PF00335.15 ETO19821.1 - 0.0016 17.7 0.0 0.046 12.9 0.0 2.2 2 0 0 2 2 2 1 Tetraspanin family DUF202 PF02656.10 ETO19821.1 - 0.049 13.8 1.0 1.7 8.9 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF202) LMBR1 PF04791.11 ETO19821.1 - 0.056 12.0 0.0 0.18 10.3 0.0 1.7 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF4381 PF14316.1 ETO19821.1 - 0.14 12.2 0.1 0.58 10.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) PspB PF06667.7 ETO19821.1 - 0.17 11.8 0.0 0.71 9.8 0.0 1.9 2 0 0 2 2 2 0 Phage shock protein B ETRAMP PF09716.5 ETO19821.1 - 8.5 6.4 7.7 10 6.1 0.1 3.2 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) GPCR_chapero_1 PF11904.3 ETO19823.1 - 1.8e-05 24.0 0.7 1.8e-05 24.0 0.5 2.3 2 1 1 3 3 3 1 GPCR-chaperone Ank_2 PF12796.2 ETO19823.1 - 3.4e-05 24.1 0.0 3.4e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO19823.1 - 0.00016 21.3 0.0 0.017 14.9 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Sigma70_ner PF04546.8 ETO19823.1 - 3.5 7.1 10.9 3.3 7.2 1.2 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region WASH-7_N PF14745.1 ETO19824.1 - 9e-18 63.7 0.2 1.2e-17 63.3 0.1 1.1 1 0 0 1 1 1 1 WASH complex subunit 7, N-terminal AATF-Che1 PF13339.1 ETO19824.1 - 0.033 14.3 2.2 1.4 9.1 0.5 2.2 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Serglycin PF04360.7 ETO19826.1 - 0.77 9.4 3.8 1.4 8.6 0.2 2.3 1 1 1 2 2 2 0 Serglycin W2 PF02020.13 ETO19827.1 - 0.013 15.3 0.5 0.031 14.2 0.3 1.6 1 0 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon Halogen_Hydrol PF10112.4 ETO19827.1 - 0.03 13.7 0.3 0.066 12.6 0.1 1.6 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein TerB PF05099.8 ETO19827.1 - 0.37 10.5 3.0 3.5 7.3 0.1 2.4 1 1 1 2 2 2 0 Tellurite resistance protein TerB DUF2067 PF09840.4 ETO19828.1 - 0.012 15.1 1.0 0.026 14.0 0.5 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2067) WEMBL PF05701.6 ETO19828.1 - 0.049 12.0 8.9 0.055 11.9 6.2 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light MAD PF05557.8 ETO19828.1 - 0.078 11.0 12.2 0.094 10.7 8.4 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF2353 PF09789.4 ETO19828.1 - 0.1 11.8 9.6 0.12 11.6 6.7 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) FixG_C PF11614.3 ETO19828.1 - 0.16 12.0 2.4 0.26 11.3 0.7 1.9 1 1 1 2 2 2 0 IG-like fold at C-terminal of FixG, putative oxidoreductase IncA PF04156.9 ETO19828.1 - 0.39 10.2 18.5 0.82 9.2 12.8 1.5 1 1 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 ETO19828.1 - 0.44 8.3 7.5 0.51 8.1 5.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1359 PF07097.6 ETO19828.1 - 0.64 10.0 6.0 2.4 8.2 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1359) APG6 PF04111.7 ETO19828.1 - 0.79 8.7 12.0 0.9 8.5 8.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Prefoldin_3 PF13758.1 ETO19828.1 - 0.99 9.2 6.5 9.3 6.0 0.3 2.2 1 1 1 2 2 2 0 Prefoldin subunit Mod_r PF07200.8 ETO19828.1 - 1.8 8.4 15.9 0.15 11.9 3.9 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF972 PF06156.8 ETO19828.1 - 2.6 8.4 15.5 0.34 11.2 6.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Pinin_SDK_memA PF04696.8 ETO19828.1 - 3.1 7.4 10.4 4.8 6.8 7.2 1.4 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region DUF2968 PF11180.3 ETO19828.1 - 4.8 6.5 12.7 1.1 8.6 6.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Nup54 PF13874.1 ETO19828.1 - 5 6.7 11.5 6.5 6.4 8.0 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Sec20 PF03908.8 ETO19828.1 - 5.7 6.7 8.9 1.2 8.8 2.0 2.4 1 1 2 3 3 3 0 Sec20 BTB PF00651.26 ETO19829.1 - 3.1e-08 33.5 0.1 0.0019 18.1 0.0 2.6 3 0 0 3 3 3 2 BTB/POZ domain IBP39 PF11422.3 ETO19829.1 - 0.004 16.6 0.0 0.01 15.3 0.0 1.6 1 0 0 1 1 1 1 Initiator binding protein 39 kDa CgtA PF06306.6 ETO19829.1 - 0.017 14.3 0.2 0.028 13.6 0.1 1.3 1 0 0 1 1 1 0 Beta-1,4-N-acetylgalactosaminyltransferase (CgtA) CENP-B_dimeris PF09026.5 ETO19829.1 - 4 7.7 8.1 23 5.2 2.8 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Kinesin PF00225.18 ETO19830.1 - 2.2e-14 52.8 0.0 2.6e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Kinesin PF00225.18 ETO19831.1 - 1.2e-51 175.4 1.1 4.9e-30 104.3 0.0 4.3 5 0 0 5 5 5 2 Kinesin motor domain Peptidase_C3 PF00548.15 ETO19831.1 - 1.6 8.5 7.1 0.34 10.7 0.2 3.0 3 0 0 3 3 3 0 3C cysteine protease (picornain 3C) Ras PF00071.17 ETO19833.1 - 3.5e-32 111.0 0.1 3.9e-32 110.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO19833.1 - 2.2e-16 60.4 0.1 2.6e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 ETO19833.1 - 3.9e-07 30.0 0.0 4.7e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 ETO19833.1 - 2.2e-05 23.7 0.0 2.6e-05 23.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO19833.1 - 0.008 15.6 0.1 0.28 10.5 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Glyco_tran_WbsX PF14307.1 ETO19833.1 - 0.14 11.2 0.0 0.21 10.7 0.0 1.2 1 1 0 1 1 1 0 Glycosyltransferase WbsX Kelch_1 PF01344.20 ETO19834.1 - 9e-21 73.1 7.2 6.2e-07 28.8 0.1 4.2 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.1 ETO19834.1 - 1.1e-14 53.8 0.2 0.024 14.4 0.0 4.7 3 1 1 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO19834.1 - 1.1e-14 54.0 0.3 0.00045 20.3 0.0 4.9 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO19834.1 - 1.8e-14 53.1 0.1 0.0006 19.8 0.0 4.5 2 2 2 4 4 4 3 Kelch motif Kelch_2 PF07646.10 ETO19834.1 - 3.2e-08 33.0 1.1 0.0018 18.0 0.0 4.4 3 1 0 3 3 3 3 Kelch motif Aldedh PF00171.17 ETO19836.1 - 7.3e-14 50.9 0.4 8.8e-14 50.6 0.3 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3046 PF11248.3 ETO19836.1 - 0.033 14.1 1.2 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3046) OmdA PF13376.1 ETO19836.1 - 0.085 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated DUF3040 PF11239.3 ETO19837.1 - 0.37 10.8 2.0 0.78 9.8 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Kelch_6 PF13964.1 ETO19838.1 - 9.8e-06 25.5 1.3 0.29 11.3 0.0 4.3 4 1 1 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO19838.1 - 0.07 12.6 0.5 1.3 8.5 0.0 3.2 4 0 0 4 4 4 0 Kelch motif Folate_carrier PF01770.13 ETO19840.1 - 5.6e-21 74.5 0.1 8.5e-21 73.9 0.1 1.3 1 0 0 1 1 1 1 Reduced folate carrier CAP_GLY PF01302.20 ETO19841.1 - 6.6e-13 48.1 0.0 1.3e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain TAT_ubiq PF07706.7 ETO19842.1 - 0.12 12.3 3.5 4 7.4 0.1 2.6 2 1 0 2 2 2 0 Aminotransferase ubiquitination site SipA PF09052.5 ETO19842.1 - 5.1 5.3 8.2 5.9 5.1 5.7 1.1 1 0 0 1 1 1 0 Salmonella invasion protein A Pkinase PF00069.20 ETO19843.1 - 0.0012 18.0 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Tetrabrachion PF11401.3 ETO19843.1 - 0.047 13.4 0.0 0.093 12.5 0.0 1.4 1 0 0 1 1 1 0 Tetrabrachion Pkinase PF00069.20 ETO19844.1 - 1e-31 110.0 3.5 1.2e-18 67.1 1.7 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO19844.1 - 2.2e-10 40.0 5.2 0.00019 20.5 0.0 2.7 1 1 0 2 2 2 2 Protein tyrosine kinase RNA_pol_Rpb1_1 PF04997.7 ETO19844.1 - 0.0012 18.1 2.0 0.24 10.6 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase Rpb1, domain 1 MspA PF09203.6 ETO19844.1 - 0.048 13.1 1.0 0.077 12.4 0.7 1.3 1 0 0 1 1 1 0 MspA Methyltransf_23 PF13489.1 ETO19845.1 - 9.5e-13 48.1 0.0 1.6e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO19845.1 - 2.9e-12 46.4 0.0 7.6e-12 45.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO19845.1 - 5.3e-09 36.4 0.1 1.3e-08 35.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETO19845.1 - 3e-07 30.8 0.0 1.7e-06 28.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETO19845.1 - 1.5e-06 28.5 0.0 3.2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO19845.1 - 9.7e-06 26.1 0.0 1.8e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 ETO19845.1 - 0.00078 19.4 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 ETO19845.1 - 0.024 14.6 0.0 0.1 12.6 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 ETO19845.1 - 0.036 13.1 0.0 0.15 11.1 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 ETO19845.1 - 0.057 13.0 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain zf-RING_2 PF13639.1 ETO19847.1 - 6.2e-15 54.7 3.7 1e-14 54.0 2.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO19847.1 - 7.6e-08 32.2 4.7 1.2e-07 31.6 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO19847.1 - 4.8e-07 29.3 3.1 7.7e-07 28.6 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO19847.1 - 5.1e-07 29.2 2.9 7.4e-07 28.7 2.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETO19847.1 - 1.2e-06 28.4 3.3 2.6e-06 27.4 2.3 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 ETO19847.1 - 0.00012 21.7 2.2 0.00019 21.0 1.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 ETO19847.1 - 0.0042 16.8 1.2 0.0082 15.9 0.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.1 ETO19847.1 - 0.0074 15.9 3.6 0.055 13.2 2.5 2.0 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 FANCL_C PF11793.3 ETO19847.1 - 0.015 15.2 5.4 0.17 11.8 3.8 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 ETO19847.1 - 0.016 15.0 1.1 0.048 13.5 0.8 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 ETO19847.1 - 0.019 14.6 0.9 0.072 12.8 0.7 2.1 1 1 0 1 1 1 0 RING-type zinc-finger PHD PF00628.24 ETO19847.1 - 0.097 12.3 2.9 0.2 11.3 2.0 1.6 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.2 ETO19847.1 - 0.17 11.9 2.6 0.4 10.7 1.8 1.6 1 1 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.6 ETO19847.1 - 0.19 11.7 1.1 0.32 11.0 0.7 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 ETO19847.1 - 0.6 9.7 2.7 1 8.9 1.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.16 ETO19848.1 - 6e-06 26.0 5.0 6e-06 26.0 3.5 1.9 2 0 0 2 2 2 1 IBR domain STE2 PF02116.10 ETO19849.1 - 0.027 13.5 0.0 0.042 12.8 0.0 1.3 1 0 0 1 1 1 0 Fungal pheromone mating factor STE2 GPCR LssY_C PF14067.1 ETO19849.1 - 0.11 11.4 0.1 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 LssY C-terminus PUB PF09409.5 ETO19849.1 - 0.37 10.5 3.2 0.57 9.9 0.3 2.6 1 1 1 2 2 2 0 PUB domain zf-TRAF PF02176.13 ETO19850.1 - 3.9e-06 27.1 1.8 3.9e-06 27.1 1.3 2.3 2 1 0 2 2 2 1 TRAF-type zinc finger DUF723 PF05265.8 ETO19850.1 - 0.16 11.7 0.1 0.16 11.7 0.1 2.4 3 1 1 4 4 4 0 Protein of unknown function (DUF723) NAD_binding_11 PF14833.1 ETO19851.1 - 6e-09 36.0 0.0 7.8e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 ETO19852.1 - 1.1e-16 61.0 0.0 1.5e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 ETO19852.1 - 2.2e-07 30.1 0.0 3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 ETO19852.1 - 0.0041 17.6 0.0 0.0062 17.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 ETO19852.1 - 0.0051 17.2 0.0 0.0094 16.3 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 ETO19852.1 - 0.011 15.0 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain UDPG_MGDP_dh_N PF03721.9 ETO19852.1 - 0.019 14.3 0.6 1.5 8.1 0.2 2.2 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Peptidase_S10 PF00450.17 ETO19853.1 - 3.4e-25 89.0 0.3 3.9e-25 88.8 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase IPP-2 PF04979.9 ETO19854.1 - 0.099 12.8 7.9 0.22 11.7 5.5 1.5 1 0 0 1 1 1 0 Protein phosphatase inhibitor 2 (IPP-2) DUF4446 PF14584.1 ETO19854.1 - 0.14 11.9 6.4 2.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Med15 PF09606.5 ETO19854.1 - 0.21 9.7 48.3 0.31 9.2 33.5 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SprA-related PF12118.3 ETO19854.1 - 0.33 10.2 20.9 0.63 9.3 14.5 1.4 1 0 0 1 1 1 0 SprA-related family LCD1 PF09798.4 ETO19854.1 - 1 7.2 10.3 1.6 6.6 7.1 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein PAT1 PF09770.4 ETO19854.1 - 1.4 7.0 31.2 1.7 6.7 21.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Kei1 PF08552.6 ETO19854.1 - 1.5 8.4 7.0 12 5.4 0.0 2.2 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 DUF1764 PF08576.5 ETO19854.1 - 2.7 8.8 9.5 2.2 9.1 4.2 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Pkinase PF00069.20 ETO19855.1 - 4.2e-06 26.1 0.1 7.3e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Sybindin PF04099.7 ETO19855.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Sybindin-like family 60KD_IMP PF02096.15 ETO19857.1 - 1.8 8.1 4.3 0.51 9.9 0.2 2.0 2 0 0 2 2 2 0 60Kd inner membrane protein Pox_VLTF3 PF04947.9 ETO19858.1 - 5e-05 22.8 0.2 9e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 Poxvirus Late Transcription Factor VLTF3 like zf-met PF12874.2 ETO19862.1 - 0.00087 19.4 0.1 0.0017 18.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 ETO19862.1 - 0.0014 18.6 0.3 0.0029 17.6 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF830 PF05708.7 ETO19863.1 - 0.087 12.8 0.2 0.1 12.5 0.2 1.2 1 0 0 1 1 1 0 Orthopoxvirus protein of unknown function (DUF830) RRM_1 PF00076.17 ETO19864.1 - 8e-17 60.6 0.0 1.5e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO19864.1 - 6.7e-10 38.8 0.0 1.1e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO19864.1 - 3.4e-07 30.0 0.1 9.1e-07 28.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 ETO19864.1 - 0.01 15.7 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 0 RNA binding domain Pkinase PF00069.20 ETO19865.1 - 0.0064 15.6 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain CHASE4 PF05228.8 ETO19866.1 - 0.071 12.6 0.8 0.13 11.8 0.6 1.4 1 0 0 1 1 1 0 CHASE4 domain DUF3450 PF11932.3 ETO19867.1 - 0.017 14.3 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) YwiC PF14256.1 ETO19867.1 - 0.39 10.7 0.1 0.39 10.7 0.0 2.3 3 1 0 3 3 3 0 YwiC-like protein Mucin PF01456.12 ETO19867.1 - 3.8 7.2 6.9 0.35 10.6 0.3 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF1516 PF07457.6 ETO19868.1 - 0.0068 16.4 2.9 0.011 15.8 2.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1516) DUF3816 PF12822.2 ETO19868.1 - 0.16 11.8 4.7 0.22 11.3 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) YwiC PF14256.1 ETO19868.1 - 0.17 11.9 1.6 0.33 11.0 1.1 1.5 1 1 0 1 1 1 0 YwiC-like protein UBA_3 PF09288.5 ETO19868.1 - 0.4 10.3 1.5 6 6.5 0.4 2.2 1 1 1 2 2 2 0 Fungal ubiquitin-associated domain RGS PF00615.14 ETO19869.1 - 4.6e-08 33.1 0.0 1.2e-07 31.8 0.0 1.7 1 1 0 1 1 1 1 Regulator of G protein signaling domain AT_hook PF02178.14 ETO19872.1 - 0.051 13.2 1.8 0.17 11.6 1.2 2.0 1 0 0 1 1 1 0 AT hook motif Reo_sigmaC PF04582.7 ETO19872.1 - 0.61 9.2 14.8 6.9 5.7 0.1 3.3 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DUF948 PF06103.6 ETO19872.1 - 6.5 6.6 29.8 0.58 10.0 6.8 4.2 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Ribosomal_S14 PF00253.16 ETO19873.1 - 0.048 13.0 3.2 0.27 10.6 1.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e HlyIII PF03006.15 ETO19874.1 - 0.018 14.4 0.2 0.023 14.1 0.1 1.1 1 0 0 1 1 1 0 Haemolysin-III related TPR_14 PF13428.1 ETO19875.1 - 0.0016 18.9 0.1 16 6.4 0.1 4.3 2 2 2 4 4 4 1 Tetratricopeptide repeat HAT PF02184.11 ETO19875.1 - 0.0089 15.7 2.6 0.31 10.8 0.1 3.4 3 0 0 3 3 3 1 HAT (Half-A-TPR) repeat NRDE-2 PF08424.5 ETO19875.1 - 0.034 13.0 0.1 0.034 13.0 0.0 2.8 3 1 0 3 3 3 0 NRDE-2, necessary for RNA interference Pkinase_Tyr PF07714.12 ETO19876.1 - 0.00013 21.1 0.0 0.00026 20.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 ETO19876.1 - 0.00096 18.3 0.0 0.00096 18.3 0.0 2.1 3 0 0 3 3 3 1 Protein kinase domain RolB_RolC PF02027.12 ETO19876.1 - 0.015 14.4 0.0 0.028 13.5 0.0 1.5 1 0 0 1 1 1 0 RolB/RolC glucosidase family IncA PF04156.9 ETO19876.1 - 0.084 12.4 0.1 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 IncA protein Zip PF02535.17 ETO19876.1 - 0.14 11.1 1.7 0.18 10.7 0.0 2.0 3 0 0 3 3 3 0 ZIP Zinc transporter Pkinase PF00069.20 ETO19877.1 - 1.1e-56 191.8 0.0 1.6e-56 191.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO19877.1 - 4.6e-31 107.8 0.0 1.3e-30 106.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETO19877.1 - 4.7e-05 23.2 0.1 0.0004 20.2 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 ETO19877.1 - 9e-05 21.6 0.0 0.00016 20.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETO19877.1 - 0.00013 21.0 0.0 0.00037 19.5 0.0 1.7 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 ETO19877.1 - 0.00054 19.3 0.0 0.00088 18.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.4 ETO19877.1 - 0.0015 17.9 0.0 0.0031 16.8 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 ETO19877.1 - 0.024 14.2 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase EF-hand_7 PF13499.1 ETO19878.1 - 3.9e-06 26.8 14.7 0.00013 22.0 3.3 4.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO19878.1 - 0.00021 20.8 0.9 0.34 10.9 0.4 3.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 ETO19878.1 - 0.0055 15.9 7.1 0.086 12.1 0.5 3.8 4 0 0 4 4 4 2 EF hand Prp18 PF02840.10 ETO19878.1 - 0.018 14.8 1.7 0.018 14.8 1.2 3.0 3 1 0 3 3 3 0 Prp18 domain Rsm1 PF08600.5 ETO19879.1 - 0.026 14.3 0.1 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 Rsm1-like DUF718 PF05336.8 ETO19880.1 - 0.093 12.5 0.6 0.21 11.4 0.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF718) DUF912 PF06024.7 ETO19881.1 - 4.7 7.3 9.6 9.8 6.2 6.6 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUSP PF06337.7 ETO19882.1 - 7.9e-17 61.4 8.4 2e-16 60.1 5.8 1.7 1 1 0 1 1 1 1 DUSP domain Lectin_N PF03954.9 ETO19882.1 - 0.0027 17.1 1.1 0.0073 15.7 0.1 2.0 2 0 0 2 2 2 1 Hepatic lectin, N-terminal domain AAA_22 PF13401.1 ETO19882.1 - 0.15 12.1 0.4 0.29 11.2 0.2 1.5 1 1 0 1 1 1 0 AAA domain FmdE PF02663.9 ETO19883.1 - 0.021 14.7 0.0 0.073 12.9 0.0 1.9 2 0 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon His_Phos_2 PF00328.17 ETO19885.1 - 0.00017 21.0 0.0 0.00019 20.8 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF3270 PF11674.3 ETO19886.1 - 1 9.4 4.0 0.28 11.2 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) YfhO PF09586.5 ETO19886.1 - 9 4.1 15.0 0.028 12.4 0.3 2.1 1 1 1 2 2 2 0 Bacterial membrane protein YfhO Ferrochelatase PF00762.14 ETO19888.1 - 3.6e-79 265.9 0.2 4.6e-79 265.6 0.1 1.1 1 0 0 1 1 1 1 Ferrochelatase MIP-T3 PF10243.4 ETO19890.1 - 0.0016 17.0 14.8 0.0019 16.7 10.3 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF3584 PF12128.3 ETO19890.1 - 0.013 12.8 15.8 0.02 12.2 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fmp27_WPPW PF10359.4 ETO19890.1 - 0.025 13.0 11.0 0.034 12.5 7.7 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DivIVA PF05103.8 ETO19890.1 - 0.13 12.3 15.6 0.028 14.4 8.5 1.6 2 0 0 2 2 2 0 DivIVA protein Muted PF14942.1 ETO19890.1 - 0.3 10.9 15.3 0.11 12.4 8.8 1.6 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein DUF641 PF04859.7 ETO19890.1 - 0.35 10.6 9.9 0.094 12.4 4.0 2.1 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) FlxA PF14282.1 ETO19890.1 - 0.36 10.8 25.4 0.16 11.8 11.9 2.4 2 0 0 2 2 2 0 FlxA-like protein OmpH PF03938.9 ETO19890.1 - 0.55 10.1 16.1 0.22 11.4 8.3 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) AATF-Che1 PF13339.1 ETO19890.1 - 0.95 9.6 14.8 0.18 11.9 7.7 1.7 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor TBPIP PF07106.8 ETO19890.1 - 1.7 8.1 16.7 5 6.6 9.1 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tho2 PF11262.3 ETO19890.1 - 2.1 7.3 9.3 3.6 6.5 6.5 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF342 PF03961.8 ETO19890.1 - 2.6 6.3 9.3 3.8 5.8 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 ETO19890.1 - 3 5.5 10.9 4.3 5.0 7.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF948 PF06103.6 ETO19890.1 - 5.9 6.8 5.4 16 5.4 3.8 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) B56 PF01603.15 ETO19891.1 - 1.2e-59 201.9 13.5 1.5e-46 158.8 4.2 2.1 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) AKAP7_RIRII_bdg PF10470.4 ETO19891.1 - 0.054 13.3 1.5 1.5 8.6 0.3 2.6 2 0 0 2 2 2 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein Lectin_C PF00059.16 ETO19892.1 - 8.1e-37 126.0 19.2 2.3e-16 60.3 0.4 4.9 4 0 0 4 4 4 3 Lectin C-type domain Fibrinogen_C PF00147.13 ETO19892.1 - 3.2e-06 26.9 0.0 7.6e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain CAP_GLY PF01302.20 ETO19894.1 - 6.5e-13 48.1 2.3 3.4e-12 45.8 1.6 2.0 1 1 0 1 1 1 1 CAP-Gly domain DUF1436 PF07262.6 ETO19895.1 - 0.0088 15.5 0.0 0.023 14.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1436) CcmH PF03918.9 ETO19895.1 - 0.052 12.5 0.0 0.12 11.3 0.0 1.6 1 0 0 1 1 1 0 Cytochrome C biogenesis protein SKG6 PF08693.5 ETO19895.1 - 0.12 11.6 3.1 0.31 10.4 2.1 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain BetaGal_dom4_5 PF13364.1 ETO19896.1 - 0.003 17.7 0.1 0.0055 16.9 0.1 1.4 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Avidin PF01382.12 ETO19896.1 - 0.065 13.5 0.3 0.15 12.3 0.1 1.6 2 0 0 2 2 2 0 Avidin family Laminin_G_3 PF13385.1 ETO19897.1 - 4.8e-15 56.1 0.5 1.1e-14 55.0 0.3 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WSC PF01822.14 ETO19897.1 - 3.1e-10 39.8 13.5 5.5e-10 39.0 9.3 1.4 1 0 0 1 1 1 1 WSC domain Pentaxin PF00354.12 ETO19897.1 - 6.6e-07 28.9 0.1 1.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Pentaxin family Sialidase PF02973.11 ETO19897.1 - 0.00037 19.5 0.2 0.00074 18.5 0.0 1.6 2 0 0 2 2 2 1 Sialidase, N-terminal domain Laminin_G_2 PF02210.19 ETO19897.1 - 0.00085 19.3 0.1 0.0013 18.7 0.1 1.2 1 0 0 1 1 1 1 Laminin G domain Ig_J_chain PF15097.1 ETO19897.1 - 0.093 12.3 0.7 2.6 7.6 0.1 2.3 2 0 0 2 2 2 0 Immunoglobulin J chain nec1 PF10379.4 ETO19897.1 - 1.7 7.8 5.1 2.4 7.3 2.0 2.0 2 0 0 2 2 2 0 Virulence protein nec1 Lectin_C PF00059.16 ETO19898.1 - 0.0072 16.9 1.7 0.015 15.9 0.7 1.9 2 0 0 2 2 2 1 Lectin C-type domain Leader_Trp PF08255.6 ETO19898.1 - 0.33 10.7 3.0 1 9.2 2.1 1.9 1 0 0 1 1 1 0 Trp-operon Leader Peptide Sulfotransfer_3 PF13469.1 ETO19899.1 - 0.0013 19.6 0.0 0.0019 19.1 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family G-alpha PF00503.15 ETO19900.1 - 1.1e-16 60.5 2.3 1.2e-16 60.3 1.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arch_ATPase PF01637.13 ETO19900.1 - 0.0036 17.0 1.1 0.0045 16.7 0.8 1.1 1 0 0 1 1 1 1 Archaeal ATPase AAA_29 PF13555.1 ETO19900.1 - 0.009 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 ETO19900.1 - 0.031 14.2 0.0 0.052 13.5 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 ETO19900.1 - 0.06 13.6 0.7 0.098 12.9 0.4 1.4 1 1 0 1 1 1 0 ABC transporter Cauli_DNA-bind PF03310.8 ETO19900.1 - 1 9.2 3.8 8.6 6.2 2.6 2.1 1 1 0 1 1 1 0 Caulimovirus DNA-binding protein CAP_GLY PF01302.20 ETO19901.1 - 5.4e-14 51.6 2.3 5.8e-14 51.5 0.0 2.1 2 0 0 2 2 2 1 CAP-Gly domain SAM_1 PF00536.25 ETO19902.1 - 0.00097 19.2 0.1 0.0024 18.0 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO19902.1 - 0.0015 18.3 0.1 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF3245 PF11595.3 ETO19903.1 - 0.054 13.7 2.6 0.073 13.3 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) DUF3812 PF12757.2 ETO19903.1 - 0.13 12.2 1.6 0.22 11.5 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3812) SAGA-Tad1 PF12767.2 ETO19904.1 - 1e-10 41.7 0.5 1e-10 41.7 0.3 3.0 2 1 1 3 3 3 1 Transcriptional regulator of RNA polII, SAGA, subunit Hid1 PF12722.2 ETO19904.1 - 0.055 11.1 14.9 0.073 10.7 10.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Daxx PF03344.10 ETO19904.1 - 0.52 8.7 19.0 0.71 8.2 13.2 1.3 1 0 0 1 1 1 0 Daxx Family Pox_Ag35 PF03286.9 ETO19904.1 - 0.83 9.1 19.6 1.8 8.0 13.6 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein BUD22 PF09073.5 ETO19904.1 - 1.6 7.6 25.1 2.9 6.8 17.4 1.4 1 0 0 1 1 1 0 BUD22 G-alpha PF00503.15 ETO19906.1 - 2.3e-15 56.2 0.1 2.3e-15 56.1 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit alpha-hel2 PF14456.1 ETO19906.1 - 0.12 11.1 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Alpha-helical domain 2 SirB PF04247.7 ETO19908.1 - 0.21 11.2 12.2 0.19 11.4 6.7 1.9 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB DUF1510 PF07423.6 ETO19909.1 - 0.018 14.4 2.7 0.024 14.0 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF3357 PF11837.3 ETO19909.1 - 0.028 14.2 3.6 0.049 13.4 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) Sigma_reg_N PF13800.1 ETO19909.1 - 0.038 14.0 0.1 0.038 14.0 0.1 2.2 2 1 1 3 3 3 0 Sigma factor regulator N-terminal DUF1183 PF06682.7 ETO19909.1 - 0.25 10.9 1.5 0.35 10.4 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) MAT1 PF06391.8 ETO19909.1 - 0.26 10.8 7.9 0.37 10.3 5.5 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 SOBP PF15279.1 ETO19909.1 - 0.34 11.2 8.7 0.4 11.0 6.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4551 PF15087.1 ETO19909.1 - 1.3 7.2 7.9 1.5 7.0 5.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PDR_CDR PF06422.7 ETO19909.1 - 4.7 6.9 13.7 0.033 13.8 1.2 2.5 2 1 1 3 3 3 0 CDR ABC transporter Ctr PF04145.10 ETO19909.1 - 4.9 7.2 9.1 2.6 8.1 3.6 2.3 1 1 1 2 2 2 0 Ctr copper transporter family Serinc PF03348.10 ETO19909.1 - 6 5.4 8.1 0.42 9.2 2.4 1.4 2 0 0 2 2 2 0 Serine incorporator (Serinc) Actin PF00022.14 ETO19910.1 - 0.0097 14.3 0.1 0.012 14.0 0.1 1.1 1 0 0 1 1 1 1 Actin CTP_synth_N PF06418.9 ETO19911.1 - 3.3e-53 180.5 1.5 1.5e-37 129.2 0.5 2.2 2 0 0 2 2 2 2 CTP synthase N-terminus XK-related PF09815.4 ETO19913.1 - 1.7e-07 30.6 6.4 3.5e-07 29.5 4.5 1.5 1 1 0 1 1 1 1 XK-related protein YhhN PF07947.9 ETO19913.1 - 0.0097 15.2 3.1 0.014 14.8 2.2 1.2 1 0 0 1 1 1 1 YhhN-like protein Acetyltransf_1 PF00583.19 ETO19914.1 - 0.00055 19.9 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETO19914.1 - 0.016 15.3 0.0 0.042 14.0 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETO19914.1 - 0.072 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1754 PF08555.5 ETO19914.1 - 0.93 10.1 26.1 0.34 11.5 4.3 2.6 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) DUF4199 PF13858.1 ETO19914.1 - 2.1 8.2 6.5 4.1 7.2 1.5 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF4199) BLVR PF06375.6 ETO19914.1 - 5.1 6.9 18.1 3.6 7.3 1.2 2.4 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Rifin_STEVOR PF02009.11 ETO19915.1 - 0.0047 16.6 0.0 0.006 16.2 0.0 1.2 1 0 0 1 1 1 1 Rifin/stevor family TMEM154 PF15102.1 ETO19915.1 - 0.017 14.8 0.2 0.025 14.2 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family Fig1 PF12351.3 ETO19915.1 - 0.21 11.4 1.5 0.3 10.9 0.4 1.7 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF912 PF06024.7 ETO19915.1 - 0.8 9.7 21.1 1.3e+03 -0.6 14.6 2.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ETRAMP PF09716.5 ETO19915.1 - 2.4 8.1 9.1 1.4e+02 2.5 5.4 3.2 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Nucleoplasmin PF03066.10 ETO19916.1 - 0.2 11.1 19.9 0.25 10.8 13.8 1.2 1 0 0 1 1 1 0 Nucleoplasmin DUF1510 PF07423.6 ETO19916.1 - 0.25 10.6 3.9 0.29 10.4 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Daxx PF03344.10 ETO19916.1 - 0.31 9.4 14.3 0.32 9.4 9.9 1.0 1 0 0 1 1 1 0 Daxx Family DUF3449 PF11931.3 ETO19916.1 - 0.35 10.3 2.5 0.37 10.2 1.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) NOA36 PF06524.7 ETO19916.1 - 0.59 9.3 14.6 0.61 9.2 10.1 1.1 1 0 0 1 1 1 0 NOA36 protein BTV_NS2 PF04514.7 ETO19916.1 - 1.1 8.0 4.5 1.3 7.7 3.1 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FAM176 PF14851.1 ETO19916.1 - 1.5 8.5 5.7 1.9 8.1 4.0 1.3 1 0 0 1 1 1 0 FAM176 family Prothymosin PF03247.9 ETO19916.1 - 2.8 8.1 22.8 3.4 7.8 15.8 1.1 1 0 0 1 1 1 0 Prothymosin/parathymosin family Sigma70_ner PF04546.8 ETO19916.1 - 2.9 7.4 15.9 3.2 7.3 11.0 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region SGT1 PF07093.6 ETO19916.1 - 2.9 6.1 9.4 3.2 6.0 6.5 1.0 1 0 0 1 1 1 0 SGT1 protein TRAP_alpha PF03896.11 ETO19916.1 - 3.2 6.6 9.1 3.3 6.6 6.3 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Upf2 PF04050.9 ETO19916.1 - 3.6 7.3 14.0 4 7.1 9.7 1.0 1 0 0 1 1 1 0 Up-frameshift suppressor 2 Trypan_PARP PF05887.6 ETO19916.1 - 3.9 7.2 6.3 4.3 7.1 4.4 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CobT PF06213.7 ETO19916.1 - 4 6.4 18.3 4.4 6.3 12.7 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT ANAPC15 PF15243.1 ETO19916.1 - 4.2 7.4 18.3 5 7.2 12.7 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 RRN3 PF05327.6 ETO19916.1 - 5.7 4.9 7.6 5.5 4.9 5.3 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 EBV-NA3 PF05009.7 ETO19916.1 - 6.6 5.8 7.4 7.1 5.7 5.1 1.1 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) VID27 PF08553.5 ETO19916.1 - 9.3 4.3 8.0 9.8 4.2 5.5 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Pox_RNA_Pol_19 PF05320.7 ETO19916.1 - 9.8 5.9 11.3 11 5.7 7.9 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF2457 PF10446.4 ETO19916.1 - 9.9 4.7 28.2 10 4.6 19.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleoporin2 PF04096.9 ETO19917.1 - 3.2e-32 111.2 0.0 3.9e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin autopeptidase Na_H_Exchanger PF00999.16 ETO19918.1 - 4.4e-06 25.4 2.1 5.9e-06 25.0 1.5 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Zip PF02535.17 ETO19918.1 - 0.0029 16.6 0.5 0.004 16.2 0.3 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter Peptidase_C78 PF07910.8 ETO19919.1 - 1e-10 41.1 0.0 1.5e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C78 PF07910.8 ETO19920.1 - 9.7e-15 54.2 0.2 3.3e-14 52.5 0.0 1.7 1 1 0 2 2 2 1 Peptidase family C78 YL1 PF05764.8 ETO19920.1 - 0.00044 19.9 3.5 0.00058 19.5 2.5 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Nop14 PF04147.7 ETO19920.1 - 0.0011 16.9 5.3 0.0013 16.8 3.6 1.0 1 0 0 1 1 1 1 Nop14-like family DUF2142 PF09913.4 ETO19920.1 - 0.057 12.0 0.1 0.08 11.5 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) SPX PF03105.14 ETO19920.1 - 0.17 11.6 21.8 0.12 12.1 6.6 2.0 2 0 0 2 2 2 0 SPX domain OATP PF03137.15 ETO19920.1 - 0.21 9.5 2.4 0.17 9.9 0.2 1.7 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family AUX_IAA PF02309.11 ETO19920.1 - 4.5 6.9 10.9 2.1 8.0 4.7 1.9 2 0 0 2 2 2 0 AUX/IAA family SAM_2 PF07647.12 ETO19924.1 - 0.00013 21.7 0.1 0.00025 20.8 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO19924.1 - 0.00013 22.0 0.1 0.00034 20.7 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) ABC2_membrane_3 PF12698.2 ETO19925.1 - 9.7e-27 93.8 19.7 1.1e-26 93.6 13.7 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF1109 PF06532.6 ETO19925.1 - 0.53 9.6 5.4 0.12 11.7 1.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1109) DUF3397 PF11877.3 ETO19925.1 - 1 9.3 11.9 0.5 10.3 5.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3397) ABC2_membrane_2 PF12679.2 ETO19925.1 - 2.9 6.6 19.2 4.6 6.0 13.3 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein PgaD PF13994.1 ETO19925.1 - 5.4 6.5 8.8 0.55 9.7 0.4 2.7 1 1 3 4 4 4 0 PgaD-like protein ABC_tran PF00005.22 ETO19926.1 - 1.1e-19 71.1 0.0 1.7e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SRP54 PF00448.17 ETO19926.1 - 0.17 11.2 0.5 0.28 10.5 0.3 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Pex24p PF06398.6 ETO19926.1 - 1.1 7.9 5.3 1.2 7.8 0.0 2.1 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin AAA_23 PF13476.1 ETO19926.1 - 1.7 8.8 4.8 0.59 10.4 1.1 1.8 2 1 0 2 2 2 0 AAA domain DUF4131 PF13567.1 ETO19926.1 - 2.6 7.4 6.8 16 4.8 4.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) MatE PF01554.13 ETO19927.1 - 4.3e-23 81.7 12.4 4.3e-23 81.7 4.2 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 ETO19927.1 - 0.015 15.0 2.0 0.015 15.0 1.4 3.4 2 1 1 3 3 3 0 Polysaccharide biosynthesis C-terminal domain DUF912 PF06024.7 ETO19927.1 - 1.4 8.9 3.7 65 3.6 0.0 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PBP1_TM PF14812.1 ETO19928.1 - 0.097 12.9 3.9 0.23 11.8 2.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WD40 PF00400.27 ETO19929.1 - 3.3e-70 229.6 22.4 8e-13 47.7 0.1 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO19929.1 - 5.9e-06 24.7 9.3 0.14 10.3 0.0 4.7 1 1 3 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO19929.1 - 0.00021 20.1 9.2 0.47 9.1 0.4 5.1 1 1 3 4 4 4 3 Nup133 N terminal like PD40 PF07676.7 ETO19929.1 - 0.13 11.9 6.1 4.6 7.0 0.0 4.7 5 1 1 6 6 6 0 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO19929.1 - 0.17 12.1 2.0 59 4.0 0.0 4.4 2 1 4 6 6 6 0 Resistin GPCR_chapero_1 PF11904.3 ETO19930.1 - 1.2e-11 44.3 7.9 1.2e-11 44.3 5.5 2.0 2 0 0 2 2 2 1 GPCR-chaperone Spt5_N PF11942.3 ETO19930.1 - 0.025 15.1 2.7 0.025 15.1 1.9 2.9 3 1 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal GPCR_chapero_1 PF11904.3 ETO19931.1 - 1.9e-24 86.3 1.2 2.3e-24 86.0 0.8 1.1 1 0 0 1 1 1 1 GPCR-chaperone COesterase PF00135.23 ETO19932.1 - 3.1e-10 39.3 0.0 6.6e-10 38.3 0.0 1.5 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.16 ETO19932.1 - 6.2e-09 35.3 0.0 2.7e-06 26.7 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 ETO19932.1 - 6.8e-09 35.6 0.0 9e-08 31.9 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETO19932.1 - 8.6e-07 28.8 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 ETO19932.1 - 2.7e-06 26.9 0.0 0.0056 16.1 0.0 2.4 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 ETO19932.1 - 0.00026 20.9 0.0 0.0006 19.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 ETO19932.1 - 0.024 13.9 0.0 0.047 12.9 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Sec3_C PF09763.4 ETO19933.1 - 0.00066 17.9 1.6 0.00094 17.4 1.1 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 RNA_pol_Rpb4 PF03874.11 ETO19933.1 - 0.37 10.8 2.9 0.34 10.9 0.8 1.7 2 0 0 2 2 2 0 RNA polymerase Rpb4 ABC_tran PF00005.22 ETO19934.1 - 4.4e-26 91.8 0.0 1.8e-15 57.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 ETO19934.1 - 4.1e-09 36.8 7.7 0.023 14.6 0.0 4.1 3 1 1 4 4 4 3 AAA domain Miro PF08477.8 ETO19934.1 - 0.0012 19.2 0.0 0.0047 17.4 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein CDC45 PF02724.9 ETO19934.1 - 0.0016 16.6 15.3 0.0025 15.9 10.6 1.2 1 0 0 1 1 1 1 CDC45-like protein AAA_22 PF13401.1 ETO19934.1 - 0.013 15.6 0.0 0.036 14.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 ETO19934.1 - 0.013 15.1 0.1 0.07 12.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 ETO19934.1 - 0.016 15.0 0.0 0.14 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 ETO19934.1 - 0.023 13.8 0.1 0.038 13.0 0.1 1.3 1 0 0 1 1 1 0 KaiC SbcCD_C PF13558.1 ETO19934.1 - 0.031 14.1 0.1 7.3 6.5 0.0 3.4 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 ETO19934.1 - 0.051 13.2 0.2 0.095 12.3 0.1 1.4 1 0 0 1 1 1 0 NACHT domain DUF4269 PF14091.1 ETO19935.1 - 0.00046 20.1 0.0 0.00078 19.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4269) NTP_transf_2 PF01909.18 ETO19935.1 - 0.00055 20.2 0.0 0.0012 19.1 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nuc-transf PF10127.4 ETO19935.1 - 0.049 12.9 0.0 0.11 11.8 0.0 1.5 2 0 0 2 2 2 0 Predicted nucleotidyltransferase Mon1 PF03164.9 ETO19936.1 - 0.00076 18.1 0.0 0.0012 17.5 0.0 1.3 1 0 0 1 1 1 1 Trafficking protein Mon1 LicD PF04991.8 ETO19936.1 - 2.7 8.0 17.0 3.3 7.7 11.1 1.7 1 1 1 2 2 2 0 LicD family PT PF04886.7 ETO19937.1 - 2.4e-46 154.7 197.3 5.1e-08 32.0 4.0 11.0 2 1 5 7 7 7 6 PT repeat Pkinase PF00069.20 ETO19938.1 - 2.5e-40 138.2 1.2 3e-40 138.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO19938.1 - 2.5e-28 98.8 0.0 4.5e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO19938.1 - 7.8e-06 25.0 0.0 1.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like DUF2660 PF10859.3 ETO19938.1 - 0.043 14.0 3.0 0.074 13.2 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2660) DUF3071 PF11268.3 ETO19938.1 - 0.08 12.6 1.1 0.15 11.8 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) DUF869 PF05911.6 ETO19938.1 - 0.089 11.0 7.9 0.12 10.5 5.5 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Spore_III_AF PF09581.5 ETO19938.1 - 0.18 11.6 5.7 0.3 10.9 3.9 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) zf-CCCH PF00642.19 ETO19940.1 - 7e-08 31.9 17.4 8.3e-07 28.5 3.8 2.7 2 1 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 ETO19940.1 - 0.23 11.5 11.7 0.29 11.1 2.9 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Methyltransf_11 PF08241.7 ETO19941.1 - 1.5e-22 79.8 0.0 3.4e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO19941.1 - 2.2e-20 72.7 0.0 3.8e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETO19941.1 - 1.4e-16 60.3 0.0 2e-16 59.7 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 ETO19941.1 - 1.6e-12 47.4 0.0 3.2e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETO19941.1 - 1.7e-12 47.5 0.0 5.3e-12 45.9 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO19941.1 - 8.5e-12 45.6 0.0 2e-11 44.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO19941.1 - 1.4e-09 38.2 0.0 3.5e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETO19941.1 - 1.3e-06 28.3 0.0 2.4e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETO19941.1 - 3.9e-06 26.3 0.0 7.3e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 ETO19941.1 - 7.2e-05 22.0 0.0 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 ETO19941.1 - 0.00064 19.3 0.0 0.00095 18.7 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.1 ETO19941.1 - 0.0032 17.1 0.0 0.013 15.2 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 ETO19941.1 - 0.014 14.4 0.4 0.089 11.8 0.0 2.2 2 2 0 2 2 2 0 Putative methyltransferase PCMT PF01135.14 ETO19941.1 - 0.12 11.9 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.5 ETO19941.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Mucin PF01456.12 ETO19942.1 - 0.0076 16.0 6.1 0.0094 15.7 4.2 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein TAF4 PF05236.9 ETO19942.1 - 0.02 14.1 6.3 0.027 13.7 4.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family GCV_T_C PF08669.6 ETO19942.1 - 0.071 13.1 0.7 0.12 12.3 0.4 1.4 1 1 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain DUF1120 PF06551.7 ETO19942.1 - 0.37 11.1 6.0 0.33 11.2 3.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1120) Ribosomal_60s PF00428.14 ETO19942.1 - 5.7 7.4 9.7 2.4 8.6 1.2 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Striatin PF08232.7 ETO19943.1 - 0.5 10.6 13.1 2.8 8.2 3.4 2.1 2 0 0 2 2 2 0 Striatin family Eapp_C PF10238.4 ETO19943.1 - 1.6 8.6 20.1 2 8.3 0.4 2.4 2 0 0 2 2 2 0 E2F-associated phosphoprotein U-box PF04564.10 ETO19944.1 - 6.6e-05 22.7 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 U-box domain Myb_DNA-binding PF00249.26 ETO19944.1 - 0.0023 17.9 0.0 0.0077 16.2 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain ODV-E18 PF10717.4 ETO19944.1 - 0.023 14.1 0.1 0.061 12.7 0.0 1.7 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 BUD22 PF09073.5 ETO19945.1 - 0.047 12.7 38.3 0.069 12.2 26.5 1.3 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 ETO19945.1 - 0.082 11.3 39.7 0.1 11.0 27.5 1.3 1 0 0 1 1 1 0 Daxx Family CENP-T PF15511.1 ETO19945.1 - 0.092 11.9 26.0 0.11 11.7 18.1 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Mitofilin PF09731.4 ETO19945.1 - 0.23 10.0 25.3 0.27 9.8 17.5 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF3299 PF11736.3 ETO19945.1 - 0.4 10.5 9.7 0.83 9.5 6.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3299) DUF1777 PF08648.7 ETO19945.1 - 3.2 7.4 35.3 4.9 6.8 24.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 ETO19945.1 - 7.2 4.9 44.9 9 4.6 31.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 LSM PF01423.17 ETO19947.1 - 9.2e-09 34.7 1.3 1.8e-08 33.8 0.1 2.1 2 0 0 2 2 2 1 LSM domain Fil_haemagg_2 PF13332.1 ETO19947.1 - 0.24 11.1 4.7 0.57 9.9 3.3 1.6 1 0 0 1 1 1 0 Haemagluttinin repeat SSP160 PF06933.6 ETO19948.1 - 0.0028 15.7 6.9 0.0028 15.7 4.7 2.8 3 0 0 3 3 3 1 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 ETO19948.1 - 0.011 15.4 7.1 0.011 15.4 4.9 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) RhoGEF PF00621.15 ETO19949.1 - 0.045 13.6 0.2 0.045 13.6 0.1 2.1 1 1 1 2 2 2 0 RhoGEF domain DUF2956 PF11169.3 ETO19949.1 - 0.13 12.2 7.9 0.21 11.5 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) L6_membrane PF05805.7 ETO19949.1 - 0.15 11.6 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 L6 membrane protein Serinc PF03348.10 ETO19949.1 - 0.2 10.3 1.0 0.22 10.1 0.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) COX16 PF14138.1 ETO19949.1 - 0.84 9.8 5.0 1.4 9.1 3.5 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 COX6B PF02297.12 ETO19950.1 - 0.17 11.9 0.3 0.17 11.9 0.2 2.1 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIb Rad4 PF03835.10 ETO19950.1 - 0.19 11.0 2.3 0.23 10.8 1.6 1.1 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain Mg_chelatase PF01078.16 ETO19951.1 - 0.0032 16.6 0.5 0.0063 15.6 0.3 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA PF00004.24 ETO19951.1 - 0.0042 17.2 3.3 0.019 15.1 0.3 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF1675 PF07897.6 ETO19951.1 - 0.1 12.4 11.1 0.14 12.0 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) AAA_17 PF13207.1 ETO19951.1 - 1.4 9.7 4.6 17 6.2 0.0 3.2 2 1 1 3 3 3 0 AAA domain TEX13 PF15186.1 ETO19952.1 - 0.25 10.9 8.3 0.54 9.8 5.7 1.5 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family DUF853 PF05872.7 ETO19952.1 - 1.1 7.4 18.8 0.016 13.5 5.5 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) TEX19 PF15553.1 ETO19952.1 - 2.4 7.9 13.8 0.57 10.0 1.1 2.5 2 1 0 2 2 2 0 Testis-expressed protein 19 Acetyltransf_1 PF00583.19 ETO19953.1 - 5.6e-10 39.1 0.0 9.3e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 ETO19953.1 - 0.072 13.2 0.0 0.15 12.2 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain NPR3 PF03666.8 ETO19955.1 - 0.16 10.4 2.7 0.16 10.4 1.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Methyltransf_12 PF08242.7 ETO19955.1 - 0.19 12.2 4.0 0.19 12.2 2.8 1.1 1 0 0 1 1 1 0 Methyltransferase domain DUF912 PF06024.7 ETO19955.1 - 1.2 9.1 6.9 1.3 9.0 4.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Eapp_C PF10238.4 ETO19955.1 - 2 8.3 9.7 2 8.3 6.7 1.0 1 0 0 1 1 1 0 E2F-associated phosphoprotein Inhibitor_I71 PF12628.2 ETO19955.1 - 2.1 7.9 10.5 2.1 7.9 7.3 1.0 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor Secretin_N_2 PF07655.8 ETO19955.1 - 8.6 6.8 12.9 9 6.7 8.9 1.1 1 0 0 1 1 1 0 Secretin N-terminal domain Aminotran_1_2 PF00155.16 ETO19956.1 - 4.7e-33 114.6 0.1 4e-19 68.7 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class I and II Beta_elim_lyase PF01212.16 ETO19956.1 - 0.00061 19.0 0.1 0.098 11.7 0.0 2.1 2 0 0 2 2 2 2 Beta-eliminating lyase GFO_IDH_MocA_C PF02894.12 ETO19957.1 - 0.014 15.1 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain HECT PF00632.20 ETO19958.1 - 1.2e-15 57.5 0.2 9.8e-15 54.4 0.0 2.1 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF1510 PF07423.6 ETO19959.1 - 0.021 14.1 0.5 0.021 14.1 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1510) Protocadherin PF08374.6 ETO19959.1 - 0.025 14.1 2.0 0.3 10.6 0.0 2.0 1 1 1 2 2 2 0 Protocadherin FAM177 PF14774.1 ETO19959.1 - 0.04 13.8 0.3 0.052 13.4 0.2 1.2 1 0 0 1 1 1 0 FAM177 family Tetraspannin PF00335.15 ETO19959.1 - 0.14 11.4 3.1 0.77 8.9 2.2 2.0 1 1 0 1 1 1 0 Tetraspanin family PH PF00169.24 ETO19960.1 - 4.1e-05 23.7 0.9 0.00019 21.5 0.6 2.2 1 1 0 1 1 1 1 PH domain Seryl_tRNA_N PF02403.17 ETO19960.1 - 0.69 9.9 5.5 8.1 6.5 0.1 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain LRR_6 PF13516.1 ETO19961.1 - 1e-24 83.7 9.1 0.0097 15.8 0.0 8.5 8 0 0 8 8 8 6 Leucine Rich repeat LRR_1 PF00560.28 ETO19961.1 - 3.3e-07 29.4 6.1 4.5 7.6 0.0 7.2 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_4 PF12799.2 ETO19961.1 - 6.1e-05 22.5 13.2 0.031 13.9 0.1 5.1 5 1 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO19961.1 - 0.00035 20.2 10.0 0.14 11.9 0.2 4.9 5 0 0 5 5 5 2 Leucine rich repeat LRR_7 PF13504.1 ETO19961.1 - 0.0011 18.8 14.7 8.1 7.1 0.0 7.8 9 0 0 9 9 9 1 Leucine rich repeat Daxx PF03344.10 ETO19961.1 - 4.2 5.7 18.0 5.7 5.3 12.4 1.1 1 0 0 1 1 1 0 Daxx Family DDHD PF02862.12 ETO19961.1 - 4.9 6.8 11.7 19 4.9 8.1 1.8 1 1 0 1 1 1 0 DDHD domain CDC45 PF02724.9 ETO19961.1 - 8.9 4.2 12.5 14 3.5 8.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Pex14_N PF04695.8 ETO19962.1 - 0.39 10.7 6.2 0.3 11.1 2.9 1.8 1 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TMEM51 PF15345.1 ETO19963.1 - 0.014 15.1 0.5 0.018 14.7 0.3 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Hid1 PF12722.2 ETO19963.1 - 0.044 11.4 11.8 0.052 11.2 8.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1510 PF07423.6 ETO19963.1 - 0.06 12.7 11.6 0.075 12.3 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Mem_trans PF03547.13 ETO19963.1 - 0.075 11.3 4.4 0.086 11.1 3.0 1.1 1 0 0 1 1 1 0 Membrane transport protein Zip PF02535.17 ETO19963.1 - 0.13 11.2 1.3 0.17 10.8 0.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter MIP-T3 PF10243.4 ETO19963.1 - 0.17 10.2 14.9 0.19 10.1 10.3 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Mucin PF01456.12 ETO19963.1 - 0.33 10.7 4.6 0.45 10.2 3.2 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein LMBR1 PF04791.11 ETO19963.1 - 0.35 9.3 3.9 0.4 9.2 2.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Ndc1_Nup PF09531.5 ETO19963.1 - 0.5 8.7 10.8 0.59 8.4 7.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Macoilin PF09726.4 ETO19963.1 - 0.69 8.1 11.6 0.76 7.9 8.0 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF2413 PF10310.4 ETO19963.1 - 0.79 8.4 14.5 0.98 8.1 10.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) CDC45 PF02724.9 ETO19963.1 - 1.3 6.9 12.4 1.5 6.7 8.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2201_N PF13203.1 ETO19963.1 - 2.2 7.3 8.2 2.8 7.0 5.7 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Neur_chan_memb PF02932.11 ETO19963.1 - 2.6 7.8 6.5 3.3 7.5 4.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Sec62 PF03839.11 ETO19963.1 - 2.8 7.2 9.4 4 6.7 6.5 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 FAM176 PF14851.1 ETO19963.1 - 4.2 7.0 5.7 6.4 6.4 4.0 1.4 1 0 0 1 1 1 0 FAM176 family CobT PF06213.7 ETO19963.1 - 5.8 5.9 12.7 7.9 5.5 8.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sec1 PF00995.18 ETO19964.1 - 1.4e-27 96.6 5.6 2e-27 96.1 3.9 1.2 1 0 0 1 1 1 1 Sec1 family F-box-like_2 PF13013.1 ETO19964.1 - 0.082 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 F-box-like domain TINF2_N PF14973.1 ETO19964.1 - 0.15 12.1 1.6 0.25 11.4 0.1 2.1 2 0 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus Podoplanin PF05808.6 ETO19965.1 - 0.39 10.2 6.7 0.82 9.2 4.7 1.6 1 0 0 1 1 1 0 Podoplanin Alpha_GJ PF03229.8 ETO19965.1 - 3.9 7.8 8.9 0.77 10.1 3.7 1.7 2 0 0 2 2 2 0 Alphavirus glycoprotein J WD40 PF00400.27 ETO19967.1 - 1.8e-65 214.6 11.4 1.6e-12 46.7 0.3 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Resistin PF06954.6 ETO19967.1 - 4.8e-05 23.5 0.5 7.5 6.9 0.0 4.6 4 1 1 5 5 5 1 Resistin PQQ_2 PF13360.1 ETO19967.1 - 0.00042 19.8 1.1 0.0013 18.2 0.8 1.8 1 1 0 1 1 1 1 PQQ-like domain Nbas_N PF15492.1 ETO19967.1 - 0.0011 18.0 1.7 4.8 6.1 0.0 4.3 1 1 3 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Tox-PL PF15644.1 ETO19967.1 - 0.0013 19.4 3.0 0.13 13.0 0.1 3.9 2 2 0 2 2 2 1 Papain fold toxin 1 DPPIV_N PF00930.16 ETO19967.1 - 0.0024 16.5 0.3 0.17 10.4 0.1 3.0 1 1 2 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Proteasome_A_N PF10584.4 ETO19967.1 - 0.0027 16.9 0.4 54 3.2 0.0 4.7 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature PD40 PF07676.7 ETO19967.1 - 0.026 14.1 7.3 18 5.0 0.0 4.7 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF1652 PF07865.6 ETO19967.1 - 0.049 13.2 0.0 3.5 7.2 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1652) DUF1442 PF07279.6 ETO19968.1 - 0.0064 15.6 0.1 0.01 14.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1442) Vfa1 PF08432.5 ETO19968.1 - 0.075 13.0 10.3 0.099 12.6 7.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4200 PF13863.1 ETO19968.1 - 0.084 12.8 22.7 0.14 12.0 15.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) HAP1_N PF04849.8 ETO19968.1 - 0.14 11.1 16.4 0.19 10.6 11.3 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Phage_GP20 PF06810.6 ETO19968.1 - 0.3 10.5 15.0 0.55 9.6 10.4 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF972 PF06156.8 ETO19968.1 - 0.36 11.1 11.5 0.62 10.4 8.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF305 PF03713.8 ETO19968.1 - 0.39 10.5 4.8 0.61 9.9 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF305) Brevenin PF03032.10 ETO19968.1 - 1 9.2 10.2 2.9 7.8 7.0 1.7 1 0 0 1 1 1 0 Brevenin/esculentin/gaegurin/rugosin family DUF4611 PF15387.1 ETO19968.1 - 1 9.5 13.7 2.1 8.5 9.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) Cytomega_UL84 PF06284.6 ETO19968.1 - 1.7 6.9 4.5 2.4 6.4 3.1 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF3740 PF12548.3 ETO19968.1 - 2.7 8.2 8.9 3.9 7.7 6.2 1.4 1 1 0 1 1 1 0 Sulfatase protein APG6 PF04111.7 ETO19968.1 - 4.3 6.2 19.2 5.4 5.9 13.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 ETO19968.1 - 5.5 6.5 19.4 8.6 5.8 13.4 1.2 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 ETO19968.1 - 6.2 5.6 13.7 3.7 6.3 7.8 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 ETO19968.1 - 8.4 4.1 12.1 12 3.6 8.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-TRAF PF02176.13 ETO19969.1 - 7.5e-06 26.2 1.3 7.5e-06 26.2 0.9 2.4 2 0 0 2 2 2 1 TRAF-type zinc finger Pkinase PF00069.20 ETO19970.1 - 2.9e-44 151.1 0.1 3.2e-43 147.7 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO19970.1 - 6.8e-22 77.7 0.1 1.1e-13 50.8 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 ETO19970.1 - 0.00039 19.5 0.1 0.00061 18.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO19970.1 - 0.0037 17.0 0.1 0.0058 16.4 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 ETO19970.1 - 0.023 14.0 0.0 0.049 12.9 0.0 1.5 1 1 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.6 ETO19970.1 - 0.029 13.1 0.0 0.035 12.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 ETO19970.1 - 0.07 12.0 0.0 0.24 10.3 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Choline_kinase PF01633.15 ETO19970.1 - 0.11 11.9 0.1 0.29 10.6 0.1 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase HLH PF00010.21 ETO19971.1 - 0.077 12.6 0.1 0.13 11.9 0.0 1.7 1 1 0 1 1 1 0 Helix-loop-helix DNA-binding domain Kelch_5 PF13854.1 ETO19971.1 - 0.083 12.8 0.0 2.9 7.9 0.0 2.2 2 0 0 2 2 2 0 Kelch motif LsmAD PF06741.8 ETO19972.1 - 0.029 14.4 2.6 0.22 11.6 1.8 2.6 1 0 0 1 1 1 0 LsmAD domain FlaA PF04620.7 ETO19972.1 - 5.7 6.2 7.9 0.21 10.9 0.1 2.2 2 1 0 2 2 2 0 Flagellar filament outer layer protein Flaa Nop14 PF04147.7 ETO19973.1 - 3.1e-05 22.1 5.7 4.3e-05 21.6 4.0 1.2 1 0 0 1 1 1 1 Nop14-like family Sporozoite_P67 PF05642.6 ETO19973.1 - 0.00067 17.6 4.4 0.00067 17.6 3.1 1.5 2 0 0 2 2 2 1 Sporozoite P67 surface antigen CDC45 PF02724.9 ETO19973.1 - 0.0026 15.8 5.0 0.0034 15.5 3.5 1.3 1 0 0 1 1 1 1 CDC45-like protein DUF1510 PF07423.6 ETO19973.1 - 0.031 13.6 9.9 0.066 12.5 6.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Tim54 PF11711.3 ETO19973.1 - 1 7.8 7.3 0.075 11.6 1.8 1.4 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 TRAP_alpha PF03896.11 ETO19973.1 - 1.4 7.8 9.6 2.5 7.0 6.6 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.7 ETO19973.1 - 5.2 6.2 15.4 9.3 5.4 10.7 1.3 1 0 0 1 1 1 0 NOA36 protein Mem_trans PF03547.13 ETO19974.1 - 3.6e-06 25.5 0.0 6.2e-05 21.4 0.0 2.8 2 1 0 2 2 2 1 Membrane transport protein Saccharop_dh PF03435.13 ETO19975.1 - 1.1e-53 182.5 0.0 1.4e-53 182.3 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase GFO_IDH_MocA PF01408.17 ETO19975.1 - 0.048 14.1 0.0 0.079 13.4 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold AstA PF04958.7 ETO19975.1 - 0.13 10.6 0.0 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit GAS PF13851.1 ETO19976.1 - 5.5e-05 22.4 9.5 5.5e-05 22.4 6.6 1.7 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding DUF2353 PF09789.4 ETO19976.1 - 0.0007 18.9 11.2 0.057 12.6 7.1 2.1 1 1 1 2 2 2 2 Uncharacterized coiled-coil protein (DUF2353) EzrA PF06160.7 ETO19976.1 - 0.0014 16.8 10.1 0.002 16.3 7.0 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Spc7 PF08317.6 ETO19976.1 - 0.002 16.8 10.8 0.002 16.8 7.5 1.5 1 1 0 1 1 1 1 Spc7 kinetochore protein ATP-synt_D PF01813.12 ETO19976.1 - 0.017 14.6 5.3 0.024 14.2 3.7 1.2 1 0 0 1 1 1 0 ATP synthase subunit D DUF972 PF06156.8 ETO19976.1 - 0.023 15.0 11.4 1.1 9.6 0.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Spc24 PF08286.6 ETO19976.1 - 0.027 14.1 12.1 0.13 12.0 0.0 3.1 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 Tropomyosin_1 PF12718.2 ETO19976.1 - 0.047 13.5 13.0 0.087 12.6 9.0 1.5 1 1 0 1 1 1 0 Tropomyosin like ATG16 PF08614.6 ETO19976.1 - 0.053 13.3 14.0 0.18 11.5 3.7 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 ETO19976.1 - 0.065 13.0 14.6 1.4 8.7 4.5 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 ETO19976.1 - 0.12 11.4 14.9 0.16 11.0 10.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Cast PF10174.4 ETO19976.1 - 0.16 10.0 15.4 8 4.3 10.9 2.1 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DASH_Hsk3 PF08227.6 ETO19976.1 - 0.18 12.0 1.6 2.4 8.4 0.2 3.2 4 0 0 4 4 4 0 DASH complex subunit Hsk3 like FH2 PF02181.18 ETO19976.1 - 0.19 10.5 6.5 0.38 9.5 4.5 1.5 1 1 0 1 1 1 0 Formin Homology 2 Domain Cep57_MT_bd PF06657.8 ETO19976.1 - 0.21 11.5 7.6 1.2 9.1 0.9 3.1 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Drf_FH3 PF06367.11 ETO19976.1 - 0.32 10.3 8.3 0.06 12.7 2.6 1.8 1 1 1 2 2 2 0 Diaphanous FH3 Domain Nup54 PF13874.1 ETO19976.1 - 0.45 10.1 8.8 1.2 8.7 6.1 1.8 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 DUF3166 PF11365.3 ETO19976.1 - 0.45 11.0 4.6 1.5 9.3 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3166) Mod_r PF07200.8 ETO19976.1 - 0.46 10.4 14.0 3.9 7.3 4.0 2.9 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Reo_sigmaC PF04582.7 ETO19976.1 - 0.46 9.6 2.5 2.4 7.2 1.7 1.9 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Seryl_tRNA_N PF02403.17 ETO19976.1 - 0.49 10.4 10.2 0.21 11.5 2.5 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain AAA_13 PF13166.1 ETO19976.1 - 0.51 8.7 9.0 0.63 8.4 6.2 1.2 1 0 0 1 1 1 0 AAA domain DUF1664 PF07889.7 ETO19976.1 - 0.56 10.0 7.4 0.18 11.5 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF720 PF05302.6 ETO19976.1 - 0.83 9.4 10.4 1.3 8.8 7.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF720) Rab5-bind PF09311.6 ETO19976.1 - 0.87 9.4 14.3 2 8.2 9.6 2.0 1 1 0 1 1 1 0 Rabaptin-like protein CHD5 PF04420.9 ETO19976.1 - 1.1 8.9 5.1 1.7 8.3 2.3 2.0 1 1 1 2 2 2 0 CHD5-like protein Cortex-I_coil PF09304.5 ETO19976.1 - 1.2 9.1 13.3 0.81 9.7 3.3 2.3 1 1 1 2 2 2 0 Cortexillin I, coiled coil KLRAQ PF10205.4 ETO19976.1 - 1.4 8.9 9.6 0.4 10.7 1.3 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein DUF489 PF04356.7 ETO19976.1 - 1.5 8.3 6.2 2.9 7.4 3.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF489) Fzo_mitofusin PF04799.8 ETO19976.1 - 1.6 8.1 10.7 0.49 9.7 1.5 2.2 1 1 1 2 2 2 0 fzo-like conserved region DUF745 PF05335.8 ETO19976.1 - 1.7 8.1 6.5 2.2 7.7 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) IncA PF04156.9 ETO19976.1 - 1.9 8.0 16.7 47 3.5 11.6 2.2 1 1 0 1 1 1 0 IncA protein NPV_P10 PF05531.7 ETO19976.1 - 2 8.7 12.1 2.7e+03 -1.4 8.4 2.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Ribosomal_L29 PF00831.18 ETO19976.1 - 2.5 7.8 8.6 3.3 7.4 0.4 3.8 2 2 0 3 3 3 0 Ribosomal L29 protein DUF904 PF06005.7 ETO19976.1 - 2.6 8.3 15.9 0.26 11.5 5.1 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF904) DUF342 PF03961.8 ETO19976.1 - 3.3 6.0 9.5 3.7 5.8 4.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Snapin_Pallidin PF14712.1 ETO19976.1 - 3.9 7.8 11.6 2.4 8.5 3.4 2.5 1 1 1 2 2 2 0 Snapin/Pallidin TSC22 PF01166.13 ETO19976.1 - 4.8 7.2 10.4 1.3 9.0 0.3 3.2 1 1 1 3 3 3 0 TSC-22/dip/bun family FlxA PF14282.1 ETO19976.1 - 6.2 6.8 15.9 1.7 8.6 2.3 2.8 1 1 2 3 3 3 0 FlxA-like protein FlaC_arch PF05377.6 ETO19976.1 - 6.4 6.7 10.5 0.28 11.1 0.4 3.0 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Atg14 PF10186.4 ETO19976.1 - 7.4 5.4 11.7 1.4 7.8 2.9 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Syntaxin-6_N PF09177.6 ETO19976.1 - 8.9 6.7 9.2 3.5 8.0 1.6 2.7 1 1 2 3 3 3 0 Syntaxin 6, N-terminal RNA_pol_Rpc4 PF05132.9 ETO19977.1 - 0.28 11.1 6.1 0.1 12.6 2.0 1.8 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF4167 PF13763.1 ETO19977.1 - 0.72 9.9 17.3 3.1 7.9 12.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4167) Menin PF05053.8 ETO19977.1 - 5.4 5.0 8.5 7.3 4.6 5.9 1.1 1 0 0 1 1 1 0 Menin Presenilin PF01080.12 ETO19978.1 - 0.49 9.1 8.3 0.59 8.8 5.7 1.1 1 0 0 1 1 1 0 Presenilin HSP70 PF00012.15 ETO19978.1 - 0.61 7.9 12.3 0.69 7.7 8.5 1.0 1 0 0 1 1 1 0 Hsp70 protein Tho2 PF11262.3 ETO19978.1 - 8.5 5.3 10.1 11 4.9 7.0 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Chal_sti_synt_N PF00195.14 ETO19979.1 - 0.091 11.9 2.4 0.1 11.8 1.7 1.2 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF3381 PF11861.3 ETO19980.1 - 8.1e-27 93.6 25.4 1.1e-25 90.0 17.6 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3381) MDH PF02315.11 ETO19980.1 - 2.2 8.2 5.2 0.51 10.3 0.1 2.3 2 0 0 2 2 2 0 Methanol dehydrogenase beta subunit Cupin_1 PF00190.17 ETO19981.1 - 0.022 14.1 1.9 0.028 13.8 0.0 1.9 2 0 0 2 2 2 0 Cupin IlvN PF07991.7 ETO19981.1 - 0.043 13.1 0.0 0.1 11.9 0.0 1.6 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain WD40 PF00400.27 ETO19983.1 - 1e-66 218.5 13.1 2.2e-13 49.5 0.1 6.5 6 1 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO19983.1 - 1.3e-07 31.4 0.6 0.018 14.7 0.0 3.5 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO19983.1 - 8e-06 24.2 6.7 0.33 9.0 0.0 4.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 PD40 PF07676.7 ETO19983.1 - 9.4e-05 21.9 7.6 2.1 8.0 0.0 5.8 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat SGL PF08450.7 ETO19983.1 - 0.00026 20.4 0.3 0.013 14.9 0.0 2.6 1 1 1 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Cytochrom_D1 PF02239.11 ETO19983.1 - 0.00029 19.2 0.0 0.59 8.3 0.0 3.0 1 1 0 2 2 2 2 Cytochrome D1 heme domain Str_synth PF03088.11 ETO19983.1 - 0.0084 16.1 0.0 0.37 10.8 0.0 3.4 3 2 3 6 6 6 1 Strictosidine synthase DUF3601 PF12208.3 ETO19983.1 - 0.0092 15.8 0.0 15 5.6 0.0 3.7 4 1 0 4 4 4 1 Domain of unknown function (DUF3601) Gmad1 PF10647.4 ETO19983.1 - 0.053 12.9 0.2 0.44 9.8 0.0 2.5 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain Mid2 PF04478.7 ETO19983.1 - 2.4 7.5 5.1 70 2.8 0.0 3.9 1 1 3 5 5 5 0 Mid2 like cell wall stress sensor WD40 PF00400.27 ETO19984.1 - 2.5e-57 188.8 12.9 1.2e-12 47.2 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO19984.1 - 3.2e-09 36.0 11.2 2.1e-05 23.4 0.2 3.7 1 1 3 4 4 4 3 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO19984.1 - 4.2e-07 28.6 0.7 0.0099 14.2 0.3 2.9 2 1 0 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.3 ETO19984.1 - 0.00063 18.0 9.6 0.14 10.2 0.5 4.6 1 1 2 4 4 4 2 Nucleoporin Nup120/160 DUF1258 PF06869.7 ETO19984.1 - 0.0044 16.1 1.5 2.4 7.1 0.1 3.6 2 2 2 4 4 4 1 Protein of unknown function (DUF1258) DUF4275 PF14101.1 ETO19984.1 - 0.012 15.6 0.0 1.1 9.3 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4275) DUF1513 PF07433.6 ETO19984.1 - 0.039 12.8 0.2 4.4 6.1 0.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1513) RabGAP-TBC PF00566.13 ETO19985.1 - 0.00032 20.2 0.7 0.00032 20.2 0.5 2.6 1 1 1 2 2 2 1 Rab-GTPase-TBC domain Umbravirus_LDM PF04817.7 ETO19985.1 - 0.0031 16.6 3.1 0.0045 16.1 2.1 1.2 1 0 0 1 1 1 1 Umbravirus long distance movement (LDM) family RabGAP-TBC PF00566.13 ETO19986.1 - 1.4e-23 83.5 2.0 2e-23 82.9 1.4 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain L27_1 PF09058.5 ETO19986.1 - 0.15 11.9 0.5 1.4 8.8 0.3 2.4 1 1 0 1 1 1 0 L27_1 Ank_2 PF12796.2 ETO19987.1 - 0.016 15.5 0.2 0.11 12.8 0.1 2.3 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) Ank PF00023.25 ETO19987.1 - 0.024 14.4 0.2 7.6 6.5 0.1 2.7 3 0 0 3 3 3 0 Ankyrin repeat FTO_CTD PF12934.2 ETO19987.1 - 0.084 12.4 0.3 0.19 11.2 0.2 1.5 1 0 0 1 1 1 0 FTO C-terminal domain Ank_4 PF13637.1 ETO19987.1 - 0.097 13.2 0.6 1.9 9.1 0.1 2.4 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO19987.1 - 0.2 11.9 0.9 0.97 9.7 0.4 2.3 2 1 1 3 3 3 0 Ankyrin repeats (many copies) V_ATPase_I PF01496.14 ETO19988.1 - 1.2e-168 562.4 10.4 1.4e-168 562.1 7.2 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family RWD PF05773.17 ETO19989.1 - 3.6e-15 55.8 0.5 6.4e-15 55.0 0.4 1.4 1 0 0 1 1 1 1 RWD domain PAPS_reduct PF01507.14 ETO19992.1 - 0.0088 15.8 0.2 1.9 8.2 0.0 2.3 2 0 0 2 2 2 2 Phosphoadenosine phosphosulfate reductase family Tape_meas_lam_C PF09718.5 ETO19992.1 - 0.044 13.6 0.3 0.078 12.8 0.2 1.3 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) zf-UBR PF02207.15 ETO19993.1 - 0.66 9.7 10.1 0.11 12.2 2.7 2.2 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) NACHT PF05729.7 ETO19994.1 - 7.1e-18 64.8 0.0 1.7e-17 63.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain BSP_II PF05432.6 ETO19994.1 - 0.00073 18.8 18.9 0.0012 18.1 13.1 1.3 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) RNA_pol_3_Rpc31 PF11705.3 ETO19994.1 - 0.0084 16.0 15.4 0.021 14.7 10.7 1.7 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 AAA_22 PF13401.1 ETO19994.1 - 0.012 15.7 0.2 0.11 12.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 ETO19994.1 - 0.015 14.7 0.0 0.033 13.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 ETO19994.1 - 0.022 14.9 2.2 4.6 7.4 0.0 3.8 3 1 1 4 4 4 0 RNA helicase AAA_16 PF13191.1 ETO19994.1 - 0.046 13.7 0.0 1.7 8.6 0.0 2.4 1 1 1 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 ETO19994.1 - 0.066 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family TraH_2 PF06871.6 ETO19994.1 - 0.18 11.2 4.0 0.34 10.3 2.8 1.4 1 0 0 1 1 1 0 TraH_2 NOA36 PF06524.7 ETO19994.1 - 0.37 10.0 7.1 0.59 9.3 5.0 1.4 1 0 0 1 1 1 0 NOA36 protein Daxx PF03344.10 ETO19994.1 - 0.76 8.1 20.2 1.1 7.6 14.0 1.1 1 0 0 1 1 1 0 Daxx Family Myc_N PF01056.13 ETO19994.1 - 0.98 8.5 10.4 1.9 7.5 7.2 1.5 1 0 0 1 1 1 0 Myc amino-terminal region FAM176 PF14851.1 ETO19994.1 - 1.1 8.9 11.1 3.3 7.3 7.7 1.8 1 0 0 1 1 1 0 FAM176 family TRAP_alpha PF03896.11 ETO19994.1 - 1.2 8.1 11.7 1.9 7.3 8.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PBP_sp32 PF07222.7 ETO19994.1 - 1.7 7.7 15.7 2.8 7.0 10.9 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CENP-B_dimeris PF09026.5 ETO19994.1 - 1.8 8.8 17.9 0.38 11.0 9.5 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DDHD PF02862.12 ETO19994.1 - 4.8 6.9 9.3 3.8 7.2 4.5 2.0 2 0 0 2 2 2 0 DDHD domain DUF2407_C PF13373.1 ETO19994.1 - 5.1 7.0 10.1 0.23 11.3 2.0 2.4 3 0 0 3 3 3 0 DUF2407 C-terminal domain Pox_Ag35 PF03286.9 ETO19994.1 - 5.9 6.3 17.7 0.78 9.2 8.8 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Vfa1 PF08432.5 ETO19994.1 - 6.4 6.7 21.5 5.4 6.9 13.6 1.7 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nucleoplasmin PF03066.10 ETO19994.1 - 8 5.9 21.7 8.4 5.8 13.8 2.0 2 0 0 2 2 2 0 Nucleoplasmin SPRY PF00622.23 ETO19995.1 - 0.0023 17.9 0.1 0.0033 17.4 0.1 1.5 1 1 0 1 1 1 1 SPRY domain G-alpha PF00503.15 ETO19996.1 - 3.4e-05 22.7 0.2 0.0001 21.1 0.2 1.8 1 1 0 1 1 1 1 G-protein alpha subunit SMI1_KNR4 PF09346.5 ETO19996.1 - 0.095 12.7 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) AKNA PF12443.3 ETO19997.1 - 0.042 13.8 3.0 1 9.3 0.5 2.4 2 0 0 2 2 2 0 AT-hook-containing transcription factor Rsbr_N PF08678.5 ETO19997.1 - 0.06 13.2 3.4 0.12 12.2 2.4 1.5 1 0 0 1 1 1 0 Rsbr N terminal FliJ PF02050.11 ETO19997.1 - 0.063 13.3 6.7 1.2 9.1 3.1 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein MbeD_MobD PF04899.7 ETO19997.1 - 0.087 12.7 4.7 2.9 7.8 0.6 2.6 2 1 0 2 2 2 0 MbeD/MobD like ACCA PF03255.9 ETO19997.1 - 0.21 11.1 3.2 0.3 10.6 0.7 2.1 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit HALZ PF02183.13 ETO19997.1 - 0.28 10.9 9.3 0.54 10.0 0.8 2.9 2 1 1 3 3 3 0 Homeobox associated leucine zipper DivIC PF04977.10 ETO19997.1 - 0.54 9.7 11.6 4.4 6.8 2.8 3.1 3 0 0 3 3 3 0 Septum formation initiator IncA PF04156.9 ETO19997.1 - 0.62 9.6 6.4 13 5.2 0.0 2.1 2 0 0 2 2 2 0 IncA protein Tropomyosin_1 PF12718.2 ETO19997.1 - 0.74 9.6 16.8 0.12 12.2 2.3 3.0 2 1 1 3 3 3 0 Tropomyosin like DUF2051 PF09738.4 ETO19997.1 - 0.91 8.7 12.4 0.17 11.1 4.8 2.0 2 0 0 2 2 2 0 Double stranded RNA binding protein (DUF2051) bZIP_2 PF07716.10 ETO19997.1 - 3.8 7.3 13.1 4.7 7.1 3.0 2.7 2 0 0 2 2 2 0 Basic region leucine zipper PARP PF00644.15 ETO19998.1 - 1.8e-06 27.5 0.1 1.8e-06 27.5 0.0 2.1 2 1 1 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain IBR PF01485.16 ETO19998.1 - 0.0016 18.2 6.2 0.0016 18.2 4.3 4.0 1 1 1 2 2 2 1 IBR domain UFC1 PF08694.6 ETO19998.1 - 0.075 12.5 2.6 0.11 11.9 1.3 1.6 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 cwf18 PF08315.7 ETO19998.1 - 3.2 8.2 9.4 2.2 8.7 0.3 2.4 2 0 0 2 2 2 0 cwf18 pre-mRNA splicing factor EFP_N PF08207.7 ETO19999.1 - 0.02 14.7 0.4 0.14 12.0 0.1 2.3 2 1 0 2 2 2 0 Elongation factor P (EF-P) KOW-like domain DUF2693 PF10902.3 ETO19999.1 - 3.5 7.6 8.5 0.49 10.3 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2693) His_kinase PF06580.8 ETO20000.1 - 0.0099 15.7 0.1 0.037 13.9 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase SAM_1 PF00536.25 ETO20001.1 - 0.0039 17.3 0.0 0.0065 16.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO20001.1 - 0.017 14.9 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF948 PF06103.6 ETO20001.1 - 0.21 11.4 2.3 5.2 7.0 0.9 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) PepSY_2 PF13670.1 ETO20002.1 - 1.2 9.0 5.1 2.6 8.0 1.8 2.2 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Apis_Csd PF11671.3 ETO20003.1 - 1.9 8.2 11.7 2.1 8.1 8.1 1.1 1 0 0 1 1 1 0 Complementary sex determiner protein DUF912 PF06024.7 ETO20003.1 - 4.2 7.4 7.6 4.2 7.4 5.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Secretin_N_2 PF07655.8 ETO20003.1 - 7.9 6.9 12.9 9 6.7 8.9 1.1 1 0 0 1 1 1 0 Secretin N-terminal domain B56 PF01603.15 ETO20004.1 - 1.1e-44 152.6 4.7 1.7e-44 152.1 3.2 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Beach PF02138.13 ETO20005.1 - 1.2e-100 336.3 0.1 5.7e-100 334.2 0.1 2.3 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 ETO20005.1 - 6.8e-09 35.5 0.7 4.4e-08 32.9 0.2 2.8 3 1 0 3 3 3 1 PH domain associated with Beige/BEACH WD40 PF00400.27 ETO20005.1 - 5.5e-08 32.3 0.5 5.3e-05 22.9 0.0 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat Metallophos PF00149.23 ETO20006.1 - 6.7e-09 35.4 1.7 1.7e-08 34.1 1.2 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.6 ETO20006.1 - 2.4e-05 22.6 0.2 0.0068 14.5 0.0 2.4 2 1 0 2 2 2 2 Firmicute fructose-1,6-bisphosphatase Metallophos_2 PF12850.2 ETO20006.1 - 0.026 14.3 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Plus-3 PF03126.13 ETO20007.1 - 3.2e-14 52.8 0.0 1.4e-12 47.5 0.0 3.0 1 1 0 1 1 1 1 Plus-3 domain DUF4456 PF14644.1 ETO20008.1 - 0.021 14.0 0.1 0.038 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) Laminin_G_3 PF13385.1 ETO20009.1 - 0.0016 18.7 0.1 0.0046 17.1 0.0 1.7 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Ribosomal_S27e PF01667.12 ETO20009.1 - 0.011 15.2 0.1 0.031 13.8 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein S27 DUF1027 PF06265.6 ETO20009.1 - 0.1 12.5 0.1 0.8 9.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1027) zf-HC5HC2H_2 PF13832.1 ETO20010.1 - 8.6e-21 74.0 5.8 8.6e-21 74.0 4.1 2.9 3 1 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 ETO20010.1 - 1.7e-16 60.1 2.0 1.7e-16 60.1 1.4 3.3 2 1 1 3 3 3 1 PHD-like zinc-binding domain PHD PF00628.24 ETO20010.1 - 5.9e-09 35.4 34.3 3.1e-05 23.5 3.7 4.4 4 1 0 4 4 4 3 PHD-finger PHD_2 PF13831.1 ETO20010.1 - 5.6e-08 31.9 4.5 5.6e-08 31.9 3.1 5.6 6 0 0 6 6 6 3 PHD-finger C1_1 PF00130.17 ETO20010.1 - 6.4e-06 25.7 21.2 0.011 15.4 1.4 3.6 3 0 0 3 3 3 3 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 ETO20010.1 - 0.0037 16.9 29.4 0.013 15.1 2.6 3.3 3 0 0 3 3 3 2 Prokaryotic RING finger family 1 Vps39_2 PF10367.4 ETO20010.1 - 0.23 11.6 0.3 0.23 11.6 0.2 3.1 3 1 1 4 4 4 0 Vacuolar sorting protein 39 domain 2 zf-PHD-like PF15446.1 ETO20010.1 - 1.8 7.8 22.4 0.16 11.2 2.6 3.3 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain COG2 PF06148.6 ETO20011.1 - 0.0062 16.4 3.9 0.0062 16.4 2.7 4.5 4 2 1 5 5 5 1 COG (conserved oligomeric Golgi) complex component, COG2 IncA PF04156.9 ETO20011.1 - 0.0093 15.5 59.4 0.32 10.5 9.8 4.2 2 1 2 4 4 4 4 IncA protein GAS PF13851.1 ETO20011.1 - 0.23 10.6 65.5 0.49 9.5 1.1 4.2 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding LPP PF04728.8 ETO20011.1 - 0.44 10.3 4.3 2 8.2 0.0 3.7 4 1 0 4 4 4 0 Lipoprotein leucine-zipper T2SF PF00482.18 ETO20011.1 - 1.9 8.3 4.1 7.5 6.4 0.2 3.0 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F CR6_interact PF10147.4 ETO20012.1 - 0.028 13.7 0.8 0.042 13.1 0.6 1.4 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Mito_fiss_reg PF05308.6 ETO20012.1 - 0.27 10.5 7.7 0.45 9.8 5.3 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator zf-H2C2_2 PF13465.1 ETO20013.1 - 1.5e-05 24.9 0.9 1.5e-05 24.9 0.6 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 ETO20013.1 - 4.8e-05 23.4 13.7 0.027 14.7 2.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETO20013.1 - 9.6e-05 22.4 10.2 0.032 14.5 1.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 ETO20013.1 - 0.00082 19.4 6.3 0.097 12.8 0.6 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 ETO20013.1 - 0.01 15.9 8.5 0.44 10.8 1.7 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-Di19 PF05605.7 ETO20013.1 - 0.022 14.8 7.7 0.15 12.2 5.3 2.1 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-FCS PF06467.9 ETO20013.1 - 0.038 13.6 3.2 4.1 7.1 0.2 2.7 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DUF4613 PF15390.1 ETO20013.1 - 0.16 10.1 10.0 0.21 9.7 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) zf-H2C2_5 PF13909.1 ETO20013.1 - 0.37 11.1 6.3 0.66 10.3 2.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 ETO20013.1 - 2.6 8.0 7.6 13 5.8 1.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger SUZ PF12752.2 ETO20013.1 - 6.9 7.2 9.3 9.4 6.8 0.0 3.1 2 2 0 2 2 2 0 SUZ domain WD40 PF00400.27 ETO20014.1 - 1.9e-50 167.0 22.5 2.6e-10 39.7 0.3 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO20014.1 - 9.1e-09 33.9 3.0 0.38 8.8 0.0 5.7 3 2 2 5 5 5 5 Nucleoporin Nup120/160 Transketolase_N PF00456.16 ETO20015.1 - 3.5e-129 430.3 0.0 4.3e-129 430.1 0.0 1.0 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.1 ETO20015.1 - 2.5e-07 29.8 0.2 0.0013 17.7 0.1 2.3 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 ETO20015.1 - 5.4e-05 22.7 0.1 0.00027 20.5 0.0 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Terpene_synth PF01397.16 ETO20015.1 - 0.024 14.0 0.1 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain RCC1 PF00415.13 ETO20017.1 - 3.5e-14 52.7 1.3 2.2e-12 46.9 0.1 2.9 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO20017.1 - 0.0035 16.9 7.6 0.1 12.2 0.5 2.6 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat TRM13 PF05206.9 ETO20017.1 - 0.06 12.5 0.0 0.06 12.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase TRM13 Cas1_AcylT PF07779.7 ETO20018.1 - 1.6e-57 195.0 41.7 6e-57 193.2 28.9 1.8 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p HSP70 PF00012.15 ETO20019.1 - 0.0017 16.3 0.1 0.0048 14.8 0.0 1.6 2 0 0 2 2 2 1 Hsp70 protein DUF1820 PF08850.6 ETO20019.1 - 0.13 12.4 0.3 0.24 11.5 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1820) WD40 PF00400.27 ETO20020.1 - 1.6e-16 59.4 9.2 2.2e-09 36.8 0.3 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat eIF2A PF08662.6 ETO20020.1 - 0.0057 16.3 0.1 0.093 12.4 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO20020.1 - 0.017 13.2 0.2 0.027 12.5 0.0 1.5 2 0 0 2 2 2 0 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO20020.1 - 0.024 14.5 0.0 6 6.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3601) Pkinase PF00069.20 ETO20021.1 - 7.2e-63 212.1 0.1 1.9e-62 210.7 0.1 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO20021.1 - 4.9e-30 104.4 0.5 2.2e-28 99.0 0.1 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 ETO20021.1 - 0.026 13.5 0.0 0.54 9.1 0.0 2.2 2 0 0 2 2 2 0 Kinase-like PB1 PF00564.19 ETO20022.1 - 3.9e-12 45.6 0.0 7.7e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 PB1 domain UBA PF00627.26 ETO20023.1 - 8e-06 25.5 0.0 1.7e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain ZZ PF00569.12 ETO20023.1 - 0.0019 17.6 1.4 0.0052 16.2 1.0 1.7 1 1 0 1 1 1 1 Zinc finger, ZZ type CARDB PF07705.6 ETO20023.1 - 0.021 14.8 0.0 0.062 13.3 0.0 1.8 1 0 0 1 1 1 0 CARDB Herpes_US12 PF05363.7 ETO20024.1 - 0.016 15.6 0.1 0.016 15.6 0.1 2.3 3 0 0 3 3 3 0 Herpesvirus US12 family WW PF00397.21 ETO20025.1 - 1e-07 31.6 0.6 2.6e-07 30.3 0.4 1.7 1 0 0 1 1 1 1 WW domain DUF1515 PF07439.6 ETO20025.1 - 1.7 8.5 5.0 0.55 10.0 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Bravo_FIGEY PF13882.1 ETO20026.1 - 0.64 10.9 3.6 14 6.6 0.1 2.2 2 0 0 2 2 2 0 Bravo-like intracellular region MIP-T3 PF10243.4 ETO20027.1 - 1.1 7.7 55.5 1.4 7.3 38.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Utp14 PF04615.8 ETO20027.1 - 3.1 5.8 52.5 4.2 5.4 36.4 1.1 1 0 0 1 1 1 0 Utp14 protein Hid1 PF12722.2 ETO20027.1 - 4.3 4.9 23.5 6.1 4.3 16.3 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SOBP PF15279.1 ETO20027.1 - 4.8 7.4 8.3 6.1 7.1 5.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein GEMIN8 PF15348.1 ETO20027.1 - 5.3 7.0 27.1 4.3 7.3 10.8 2.2 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 HCO3_cotransp PF00955.16 ETO20027.1 - 7.4 5.0 7.1 1.2 7.7 0.0 2.0 2 0 0 2 2 2 0 HCO3- transporter family DUF2435 PF10363.4 ETO20028.1 - 0.0058 16.5 0.1 0.014 15.2 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2435) UCH PF00443.24 ETO20028.1 - 0.15 11.1 0.3 0.2 10.7 0.2 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase HEAT_2 PF13646.1 ETO20029.1 - 9.9e-14 51.3 0.0 9.6e-07 29.0 0.0 4.8 3 2 4 7 7 7 5 HEAT repeats HEAT PF02985.17 ETO20029.1 - 3.7e-12 45.2 0.0 0.18 11.9 0.0 7.1 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.1 ETO20029.1 - 1.6e-06 28.4 0.0 0.18 12.3 0.0 5.8 3 1 3 6 6 6 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 ETO20029.1 - 0.0014 18.9 9.3 0.035 14.4 0.4 5.3 3 3 3 6 6 6 1 Vacuolar 14 Fab1-binding region N_Asn_amidohyd PF14736.1 ETO20029.1 - 0.037 12.8 2.3 2.3 7.0 0.1 2.9 2 1 1 3 3 3 0 Protein N-terminal asparagine amidohydrolase SRA1 PF07304.6 ETO20029.1 - 0.1 12.3 2.1 6.2 6.5 0.0 3.1 3 1 0 3 3 3 0 Steroid receptor RNA activator (SRA1) DUF2435 PF10363.4 ETO20029.1 - 1.9 8.4 10.7 1.5 8.7 0.4 4.3 3 1 1 4 4 4 0 Protein of unknown function (DUF2435) WD40 PF00400.27 ETO20032.1 - 5.1e-55 181.5 17.9 1.4e-12 46.9 0.0 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat PD40 PF07676.7 ETO20032.1 - 3e-05 23.5 1.5 0.25 11.0 0.0 3.7 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO20032.1 - 0.00021 20.1 5.3 2.9 6.5 3.4 4.4 1 1 1 2 2 2 1 Nup133 N terminal like DUF1258 PF06869.7 ETO20032.1 - 0.00054 19.1 0.2 1.7 7.6 0.0 3.4 1 1 2 3 3 3 2 Protein of unknown function (DUF1258) Nbas_N PF15492.1 ETO20032.1 - 0.00085 18.4 0.6 1.5 7.8 0.0 3.0 1 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 ETO20032.1 - 0.0015 16.7 9.8 0.76 7.8 0.0 4.3 1 1 2 4 4 4 3 Nucleoporin Nup120/160 DUF3732 PF12532.3 ETO20032.1 - 0.0047 16.4 0.0 0.22 11.0 0.0 3.1 1 1 2 3 3 3 1 Protein of unknown function (DUF3732) Cytochrom_D1 PF02239.11 ETO20032.1 - 0.0066 14.7 0.8 0.37 9.0 0.1 2.4 2 1 0 2 2 2 2 Cytochrome D1 heme domain PA28_beta PF02252.13 ETO20033.1 - 2.6e-36 124.3 1.0 1e-35 122.4 0.1 2.0 2 0 0 2 2 2 1 Proteasome activator pa28 beta subunit Phospholip_A2_2 PF05826.7 ETO20033.1 - 0.22 11.5 3.0 0.21 11.5 0.6 2.0 2 0 0 2 2 2 0 Phospholipase A2 LCM PF04072.9 ETO20034.1 - 1.5e-10 40.9 0.0 3.1e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 Leucine carboxyl methyltransferase DUF965 PF06135.7 ETO20034.1 - 0.093 12.7 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF965) Trypan_PARP PF05887.6 ETO20035.1 - 0.074 12.8 19.7 0.094 12.5 13.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Arch_flagellin PF01917.11 ETO20035.1 - 0.08 12.5 0.7 0.085 12.4 0.5 1.2 1 0 0 1 1 1 0 Archaebacterial flagellin CobT PF06213.7 ETO20035.1 - 0.51 9.4 18.5 0.58 9.2 12.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT MIP-T3 PF10243.4 ETO20035.1 - 0.57 8.5 41.6 0.59 8.5 28.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2201_N PF13203.1 ETO20035.1 - 1.1 8.3 17.5 1.2 8.2 12.2 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain U79_P34 PF03064.11 ETO20035.1 - 2.6 7.4 23.0 3 7.2 15.9 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DDHD PF02862.12 ETO20035.1 - 2.9 7.6 16.3 3.7 7.2 11.3 1.2 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 ETO20035.1 - 3.3 7.5 30.0 4.5 7.0 20.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Raftlin PF15250.1 ETO20035.1 - 3.8 5.9 13.8 4.2 5.8 9.5 1.1 1 0 0 1 1 1 0 Raftlin Zip PF02535.17 ETO20035.1 - 4.5 6.1 10.0 4.6 6.1 6.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.11 ETO20035.1 - 5.1 6.9 11.7 5.4 6.8 8.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MM_CoA_mutase PF01642.17 ETO20036.1 - 9e-17 60.3 1.6 9.6e-17 60.3 1.1 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase MM_CoA_mutase PF01642.17 ETO20037.1 - 2e-97 326.5 1.8 2.7e-95 319.4 1.2 2.0 1 1 0 1 1 1 1 Methylmalonyl-CoA mutase Peptidase_C14 PF00656.17 ETO20038.1 - 4.2e-10 39.7 0.2 6.5e-10 39.1 0.1 1.4 1 0 0 1 1 1 1 Caspase domain DivIC PF04977.10 ETO20039.1 - 0.094 12.2 3.0 0.24 10.9 2.1 1.7 1 0 0 1 1 1 0 Septum formation initiator IBB PF01749.15 ETO20040.1 - 5.2e-07 29.7 3.0 5.2e-07 29.7 2.1 2.5 2 1 1 3 3 3 1 Importin beta binding domain Arm PF00514.18 ETO20040.1 - 1.2e-06 28.1 0.1 0.0052 16.5 0.0 3.1 2 1 1 3 3 3 2 Armadillo/beta-catenin-like repeat CEP170_C PF15308.1 ETO20040.1 - 0.058 11.6 5.2 0.076 11.2 3.6 1.0 1 0 0 1 1 1 0 CEP170 C-terminus Hex_IIIa PF02455.11 ETO20041.1 - 0.34 9.5 6.9 0.4 9.3 4.8 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Presenilin PF01080.12 ETO20041.1 - 5 5.8 6.3 6 5.5 4.4 1.1 1 0 0 1 1 1 0 Presenilin F-box-like PF12937.2 ETO20042.1 - 2e-05 24.2 0.2 3.3e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETO20042.1 - 0.00084 18.9 0.3 0.0018 17.8 0.2 1.4 1 0 0 1 1 1 1 F-box domain PAS_3 PF08447.6 ETO20042.1 - 0.018 15.0 0.1 0.04 14.0 0.1 1.5 1 0 0 1 1 1 0 PAS fold CwfJ_C_1 PF04677.10 ETO20043.1 - 3.4e-11 42.8 8.7 1.1e-10 41.1 6.1 1.8 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 ETO20044.1 - 2.1e-14 53.8 1.6 2.7e-14 53.4 0.0 1.9 2 1 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 Ndufs5 PF10200.4 ETO20044.1 - 0.066 13.1 1.5 0.13 12.3 1.1 1.5 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa HALZ PF02183.13 ETO20044.1 - 0.071 12.8 1.2 0.13 11.9 0.8 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF2681 PF10883.3 ETO20044.1 - 0.19 11.9 3.6 0.29 11.3 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Ndc80_HEC PF03801.8 ETO20045.1 - 3.7e-35 120.7 0.0 8.7e-35 119.5 0.0 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family GP41 PF00517.12 ETO20045.1 - 0.29 10.6 8.2 3.5 7.1 0.5 3.5 3 1 0 3 3 3 0 Retroviral envelope protein GST_C_3 PF14497.1 ETO20045.1 - 0.5 10.8 0.0 0.5 10.8 0.0 3.5 3 1 1 4 4 4 0 Glutathione S-transferase, C-terminal domain Folate_rec PF03024.9 ETO20046.1 - 1.4e-05 24.7 5.6 1.5e-05 24.6 2.8 1.7 1 1 1 2 2 2 1 Folate receptor family DUF4131 PF13567.1 ETO20046.1 - 0.024 14.0 0.6 0.15 11.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Tox-HDC PF15656.1 ETO20046.1 - 0.091 12.9 1.5 0.2 11.8 1.1 1.5 1 0 0 1 1 1 0 Toxin with a H, D/N and C signature TFIIA PF03153.8 ETO20046.1 - 1.6 8.5 32.8 2.3 8.0 22.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sec7 PF01369.15 ETO20047.1 - 1.8e-31 109.3 0.2 2.1e-29 102.5 0.0 2.8 2 0 0 2 2 2 2 Sec7 domain DUF2464 PF10240.4 ETO20047.1 - 7.5e-07 28.7 1.5 1.2e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2464) Sec7_N PF12783.2 ETO20047.1 - 0.47 9.8 14.6 0.039 13.3 1.7 4.2 4 1 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal CBS PF00571.23 ETO20048.1 - 2.4e-17 62.4 0.0 4.7e-09 35.8 0.0 3.2 3 0 0 3 3 3 2 CBS domain DASH_Dad1 PF08649.5 ETO20048.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Dad1 SHP PF03579.8 ETO20048.1 - 3.1 7.2 4.9 20 4.6 0.8 2.7 3 0 0 3 3 3 0 Small hydrophobic protein MSC PF09402.5 ETO20050.1 - 0.023 13.4 1.8 0.026 13.2 0.1 1.8 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain Myc_N PF01056.13 ETO20052.1 - 0.00092 18.4 14.5 0.00092 18.4 10.1 3.8 2 1 0 3 3 3 1 Myc amino-terminal region Mem_trans PF03547.13 ETO20052.1 - 0.0023 16.2 2.5 0.0023 16.2 1.7 2.4 2 0 0 2 2 2 1 Membrane transport protein Nucleoside_tran PF01733.13 ETO20052.1 - 0.071 12.2 3.3 0.2 10.8 2.3 1.8 1 0 0 1 1 1 0 Nucleoside transporter SecY PF00344.15 ETO20052.1 - 0.14 11.0 0.1 0.22 10.4 0.1 1.2 1 0 0 1 1 1 0 SecY translocase Otopetrin PF03189.8 ETO20052.1 - 4.4 6.2 13.4 0.091 11.7 3.4 2.1 2 0 0 2 2 2 0 Otopetrin DUF3793 PF12672.2 ETO20053.1 - 0.033 13.7 0.4 1 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3793) RPEL PF02755.10 ETO20055.1 - 8.9e-06 24.8 2.6 2.5e-05 23.4 1.0 2.2 2 0 0 2 2 2 1 RPEL repeat GAGA_bind PF06217.7 ETO20055.1 - 2.3 8.1 14.9 3.3 7.6 10.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family MSC PF09402.5 ETO20056.1 - 2.3e-07 29.8 0.2 7.2e-07 28.2 0.1 1.7 1 1 0 1 1 1 1 Man1-Src1p-C-terminal domain BAF1_ABF1 PF04684.8 ETO20058.1 - 0.021 13.6 1.8 0.024 13.4 1.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SR-25 PF10500.4 ETO20058.1 - 3 7.2 20.8 2.5 7.5 13.4 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein RNA_pol_Rpc4 PF05132.9 ETO20059.1 - 0.11 12.4 4.8 5.5 6.9 1.4 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 Peptidase_S49_N PF08496.5 ETO20059.1 - 0.12 12.1 2.9 0.18 11.6 2.0 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3682 PF12446.3 ETO20059.1 - 1.3 9.3 12.5 1.9 8.8 6.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) DEP PF00610.16 ETO20061.1 - 1.4e-09 37.5 0.1 2.6e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Daxx PF03344.10 ETO20061.1 - 7.1 4.9 44.3 15 3.9 30.4 1.7 1 1 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 ETO20061.1 - 9.8 4.7 39.5 0.16 10.6 21.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Pkinase PF00069.20 ETO20062.1 - 1.7e-61 207.6 0.5 3.7e-59 199.9 0.3 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO20062.1 - 3e-30 105.1 0.1 6.3e-28 97.5 0.1 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 ETO20062.1 - 7.4e-05 21.9 0.2 0.00013 21.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETO20062.1 - 0.033 13.1 0.0 1.3 7.8 0.0 2.2 1 1 0 2 2 2 0 Kinase-like Patched PF02460.13 ETO20063.1 - 9.4 4.0 12.3 10 3.8 8.6 1.1 1 0 0 1 1 1 0 Patched family IncA PF04156.9 ETO20064.1 - 0.0006 19.4 7.9 0.0006 19.4 5.5 2.1 1 1 1 2 2 2 1 IncA protein CENP-F_leu_zip PF10473.4 ETO20064.1 - 0.0012 18.7 17.7 0.016 15.0 1.6 2.8 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.6 ETO20064.1 - 0.0012 18.6 5.0 4 7.4 0.0 4.3 2 1 2 4 4 4 1 Flagella accessory protein C (FlaC) Seryl_tRNA_N PF02403.17 ETO20064.1 - 0.0034 17.3 12.6 0.08 12.9 0.1 2.1 1 1 1 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Reo_sigmaC PF04582.7 ETO20064.1 - 0.019 14.1 3.6 0.026 13.7 2.4 1.3 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Filament PF00038.16 ETO20064.1 - 0.027 13.9 18.9 0.67 9.3 0.4 2.5 1 1 1 2 2 2 0 Intermediate filament protein Atg14 PF10186.4 ETO20064.1 - 0.032 13.1 16.5 0.1 11.5 11.4 1.7 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Herpes_U30 PF04523.8 ETO20064.1 - 0.046 11.1 5.3 0.054 10.9 3.7 1.1 1 0 0 1 1 1 0 Herpes virus tegument protein U30 AAA_13 PF13166.1 ETO20064.1 - 0.082 11.3 11.4 0.1 11.0 7.9 1.1 1 0 0 1 1 1 0 AAA domain TMF_TATA_bd PF12325.3 ETO20064.1 - 0.097 12.4 17.4 0.96 9.1 2.2 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.7 ETO20064.1 - 0.097 12.4 9.2 0.078 12.7 2.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.1 ETO20064.1 - 0.11 12.8 13.0 0.87 9.9 3.3 2.7 1 1 0 2 2 2 0 Snapin/Pallidin FUSC PF04632.7 ETO20064.1 - 0.19 10.1 2.6 0.21 9.9 1.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2400 PF09674.5 ETO20064.1 - 0.2 11.3 6.0 0.29 10.8 2.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) CENP-K PF11802.3 ETO20064.1 - 0.45 9.6 11.5 0.54 9.4 8.0 1.1 1 0 0 1 1 1 0 Centromere-associated protein K DUF4164 PF13747.1 ETO20064.1 - 0.48 10.6 11.7 0.19 11.9 2.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Cortex-I_coil PF09304.5 ETO20064.1 - 0.57 10.2 16.9 2.5 8.1 3.9 2.6 1 1 1 2 2 2 0 Cortexillin I, coiled coil ADIP PF11559.3 ETO20064.1 - 0.58 10.0 16.2 0.073 12.9 2.7 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 ETO20064.1 - 0.74 8.8 21.4 0.067 12.2 12.0 1.3 2 0 0 2 2 2 0 Autophagy protein Apg6 Rab5-bind PF09311.6 ETO20064.1 - 0.8 9.5 20.9 4.7 7.0 14.7 1.9 1 1 0 1 1 1 0 Rabaptin-like protein TPR_MLP1_2 PF07926.7 ETO20064.1 - 0.82 9.4 20.9 4 7.1 0.3 3.1 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Syntaxin-6_N PF09177.6 ETO20064.1 - 0.84 10.0 11.1 24 5.4 6.4 2.8 1 1 0 2 2 2 0 Syntaxin 6, N-terminal Kinesin-relat_1 PF12711.2 ETO20064.1 - 0.89 10.0 11.1 2.2 8.7 6.0 2.6 1 1 1 2 2 2 0 Kinesin motor DUF1515 PF07439.6 ETO20064.1 - 0.93 9.3 9.0 0.23 11.2 1.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DUF4140 PF13600.1 ETO20064.1 - 0.95 9.9 11.6 21 5.6 3.1 3.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) COG2 PF06148.6 ETO20064.1 - 1.1 9.0 11.2 4.1 7.2 0.8 2.9 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2762 PF10960.3 ETO20064.1 - 1.3 8.8 7.5 4.7 6.9 5.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2762) WXG100 PF06013.7 ETO20064.1 - 1.3 9.0 14.5 4.1 7.4 0.8 3.6 2 2 1 3 3 3 0 Proteins of 100 residues with WXG DUF342 PF03961.8 ETO20064.1 - 1.4 7.2 12.7 0.91 7.8 6.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF972 PF06156.8 ETO20064.1 - 2.2 8.6 13.2 5.6 7.3 0.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) NPV_P10 PF05531.7 ETO20064.1 - 2.2 8.5 10.1 11 6.3 1.1 3.3 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein OmpH PF03938.9 ETO20064.1 - 2.5 7.9 20.0 6.6 6.6 13.9 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) V_ATPase_I PF01496.14 ETO20064.1 - 3.1 5.5 9.1 3.7 5.2 6.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family VGCC_beta4Aa_N PF12052.3 ETO20064.1 - 9.7 6.1 8.8 4.3 7.2 0.3 3.2 2 1 1 3 3 3 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal ALAD PF00490.16 ETO20065.1 - 1.8e-49 168.3 0.4 2e-49 168.2 0.3 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Patatin PF01734.17 ETO20066.1 - 1.2e-24 87.3 0.0 1.9e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase DEAD PF00270.24 ETO20067.1 - 3.6e-46 156.7 0.0 1.1e-45 155.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETO20067.1 - 1.4e-22 79.3 0.0 5.1e-22 77.5 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 ETO20067.1 - 4.7e-05 22.3 1.1 8.6e-05 21.4 0.0 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain SecA_DEAD PF07517.9 ETO20067.1 - 0.01 15.1 4.2 0.018 14.3 0.0 2.8 3 1 0 3 3 3 0 SecA DEAD-like domain LMBR1 PF04791.11 ETO20069.1 - 1.2e-05 24.1 0.0 0.0003 19.4 0.0 2.4 2 1 0 2 2 2 1 LMBR1-like membrane protein Gemini_mov PF01708.11 ETO20069.1 - 0.021 14.3 0.1 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 Geminivirus putative movement protein WD40 PF00400.27 ETO20070.1 - 0.00033 20.4 2.1 0.0008 19.2 0.3 2.1 2 1 0 2 2 2 1 WD domain, G-beta repeat DUF1299 PF06975.6 ETO20070.1 - 0.037 13.8 0.1 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1299) Nup160 PF11715.3 ETO20070.1 - 0.09 10.8 0.0 0.09 10.8 0.0 1.0 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DUF3637 PF12337.3 ETO20070.1 - 0.11 12.5 0.3 0.15 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3637) RVT_1 PF00078.22 ETO20071.1 - 1.9e-30 105.8 0.0 3.8e-30 104.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 ETO20071.1 - 1.4e-13 50.4 0.1 5e-13 48.6 0.0 2.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 ETO20071.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Serinc PF03348.10 ETO20072.1 - 0.088 11.5 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Nodulin PF02451.10 ETO20075.1 - 0.1 12.0 0.7 0.12 11.8 0.5 1.3 1 1 0 1 1 1 0 Nodulin Cnd1_N PF12922.2 ETO20075.1 - 4.3 6.9 17.0 10 5.6 11.8 1.7 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term Cuticle_3 PF11018.3 ETO20075.1 - 8.1 6.5 6.7 1.7 8.7 0.7 1.9 2 0 0 2 2 2 0 Pupal cuticle protein C1 cNMP_binding PF00027.24 ETO20076.1 - 4.4e-08 32.8 0.0 1.9e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Popeye PF04831.8 ETO20076.1 - 5.9e-07 29.3 0.4 1.4e-06 28.1 0.3 1.6 1 0 0 1 1 1 1 Popeye protein conserved region Alba PF01918.16 ETO20077.1 - 5e-14 51.6 0.1 8.4e-14 50.9 0.1 1.4 1 0 0 1 1 1 1 Alba Rpp20 PF12328.3 ETO20077.1 - 0.00034 20.2 2.4 0.00034 20.2 1.7 1.6 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Hat1_N PF10394.4 ETO20078.1 - 1.3e-24 87.1 2.7 1.7e-24 86.7 1.8 1.1 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Hat1_N PF10394.4 ETO20079.1 - 1.7e-05 24.9 2.1 2.2e-05 24.5 0.3 2.0 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_7 PF13508.1 ETO20079.1 - 0.0097 16.0 1.1 0.023 14.8 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain tRNA-synt_1e PF01406.14 ETO20080.1 - 1.9e-56 191.4 9.1 1.9e-56 191.4 6.3 2.4 2 1 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain DALR_2 PF09190.6 ETO20080.1 - 0.031 14.5 1.0 1.7 8.9 0.0 3.9 4 0 0 4 4 4 0 DALR domain Ribonuclease_3 PF00636.21 ETO20080.1 - 1.7 9.0 4.8 2.1 8.8 1.5 2.5 2 1 0 2 2 2 0 Ribonuclease III domain FragX_IP PF05994.6 ETO20081.1 - 8.3e-13 47.0 0.2 8.3e-13 47.0 0.1 2.1 2 0 0 2 2 1 1 Cytoplasmic Fragile-X interacting family Ycf1 PF05758.7 ETO20081.1 - 6.8e-05 20.8 9.2 6.8e-05 20.8 6.4 1.1 1 0 0 1 1 1 1 Ycf1 Borrelia_P83 PF05262.6 ETO20081.1 - 0.014 13.6 17.0 0.017 13.3 11.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Mem_trans PF03547.13 ETO20081.1 - 0.026 12.8 0.9 0.031 12.5 0.7 1.1 1 0 0 1 1 1 0 Membrane transport protein GAGA_bind PF06217.7 ETO20081.1 - 0.03 14.3 10.2 0.046 13.6 7.1 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family DDHD PF02862.12 ETO20081.1 - 0.063 13.0 8.5 0.1 12.3 5.9 1.4 1 0 0 1 1 1 0 DDHD domain Ndc1_Nup PF09531.5 ETO20081.1 - 0.13 10.6 8.1 0.18 10.1 5.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Daxx PF03344.10 ETO20081.1 - 0.15 10.5 19.0 0.18 10.2 13.2 1.1 1 0 0 1 1 1 0 Daxx Family SOBP PF15279.1 ETO20081.1 - 0.19 12.0 8.7 0.26 11.6 6.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Rtf2 PF04641.7 ETO20081.1 - 0.21 10.7 22.8 0.073 12.2 13.9 1.6 2 0 0 2 2 2 0 Rtf2 RING-finger Otopetrin PF03189.8 ETO20081.1 - 0.21 10.5 3.1 0.24 10.3 2.2 1.1 1 0 0 1 1 1 0 Otopetrin Hom_end_hint PF05203.11 ETO20081.1 - 0.22 11.2 6.7 0.28 10.8 4.6 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint TP53IP5 PF15331.1 ETO20081.1 - 0.31 10.9 11.8 0.53 10.1 8.2 1.4 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 LMBR1 PF04791.11 ETO20081.1 - 0.35 9.4 4.3 0.4 9.2 3.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein LicD PF04991.8 ETO20081.1 - 0.4 10.7 6.4 0.13 12.3 2.4 1.7 2 0 0 2 2 2 0 LicD family Hid1 PF12722.2 ETO20081.1 - 0.53 7.8 12.1 0.63 7.6 8.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RP-C_C PF11800.3 ETO20081.1 - 0.54 9.9 10.6 1.1 8.8 7.4 1.6 1 0 0 1 1 1 0 Replication protein C C-terminal region SID-1_RNA_chan PF13965.1 ETO20081.1 - 0.7 7.9 5.8 0.91 7.6 4.0 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4661 PF15576.1 ETO20081.1 - 1 8.9 6.1 1.6 8.3 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) DUF2201_N PF13203.1 ETO20081.1 - 1.8 7.6 13.5 1.4 7.9 8.5 1.5 2 0 0 2 2 2 0 Putative metallopeptidase domain DUF4045 PF13254.1 ETO20081.1 - 2.2 7.4 16.9 3.1 6.9 11.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) NARP1 PF12569.3 ETO20081.1 - 2.3 6.8 25.8 1.1 7.9 16.0 1.7 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 TEX19 PF15553.1 ETO20081.1 - 5.2 6.9 13.1 8.8 6.1 9.1 1.3 1 0 0 1 1 1 0 Testis-expressed protein 19 Pex24p PF06398.6 ETO20081.1 - 5.2 5.7 7.4 8 5.1 5.1 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin FHIPEP PF00771.15 ETO20081.1 - 5.5 5.1 8.9 8.2 4.6 6.2 1.3 1 0 0 1 1 1 0 FHIPEP family SR-25 PF10500.4 ETO20081.1 - 5.6 6.3 24.6 9.1 5.6 17.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CDC45 PF02724.9 ETO20081.1 - 6.3 4.6 22.4 8.9 4.2 15.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Cellulose_synt PF03552.9 ETO20081.1 - 6.4 4.9 8.3 8.5 4.5 5.8 1.1 1 0 0 1 1 1 0 Cellulose synthase APG6 PF04111.7 ETO20081.1 - 7.7 5.4 23.6 15 4.5 16.3 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 ETO20081.1 - 8.2 4.1 12.7 9.8 3.8 8.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1510 PF07423.6 ETO20081.1 - 9.6 5.5 30.2 15 4.8 20.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) HlyD_2 PF12700.2 ETO20083.1 - 0.071 12.2 0.3 0.093 11.8 0.2 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Atg14 PF10186.4 ETO20083.1 - 1.1 8.0 5.7 1.5 7.6 4.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-F_leu_zip PF10473.4 ETO20083.1 - 1.6 8.5 6.9 27 4.6 4.8 2.1 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ESSS PF10183.4 ETO20084.1 - 0.0015 18.9 0.1 0.0021 18.4 0.1 1.2 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF2956 PF11169.3 ETO20084.1 - 0.016 15.1 2.1 0.27 11.2 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) BatD PF13584.1 ETO20084.1 - 0.025 13.1 0.2 0.031 12.8 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance Sugar_tr PF00083.19 ETO20084.1 - 0.067 11.7 0.0 0.086 11.4 0.0 1.3 1 0 0 1 1 1 0 Sugar (and other) transporter MscS_TM PF12794.2 ETO20084.1 - 0.17 10.4 1.2 0.19 10.3 0.0 1.6 1 1 1 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 MIT PF04212.13 ETO20085.1 - 1.7e-06 27.8 7.4 1.7e-06 27.8 5.1 1.8 2 1 0 2 2 2 1 MIT (microtubule interacting and transport) domain DUF4551 PF15087.1 ETO20085.1 - 0.033 12.5 2.7 0.038 12.3 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF966 PF06136.8 ETO20085.1 - 0.052 12.9 4.2 0.062 12.7 2.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) HEPN PF05168.9 ETO20085.1 - 0.1 12.4 2.0 0.14 12.0 1.4 1.4 1 1 0 1 1 1 0 HEPN domain APG6 PF04111.7 ETO20085.1 - 0.29 10.1 9.4 0.34 9.8 6.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 4HB_MCP_1 PF12729.2 ETO20085.1 - 0.39 10.0 9.4 0.16 11.2 0.3 2.1 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction DUF4398 PF14346.1 ETO20085.1 - 0.46 10.5 12.6 3.5 7.7 8.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4398) DUF4404 PF14357.1 ETO20085.1 - 2.2 8.7 9.0 5.8 7.3 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF4407 PF14362.1 ETO20085.1 - 2.2 7.1 5.4 3.3 6.5 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HSP70 PF00012.15 ETO20085.1 - 2.3 6.0 9.7 2.9 5.6 6.7 1.0 1 0 0 1 1 1 0 Hsp70 protein DUF4175 PF13779.1 ETO20085.1 - 3.2 5.3 9.1 4.1 4.9 6.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TPR_MLP1_2 PF07926.7 ETO20085.1 - 7.7 6.2 15.8 0.15 11.7 1.5 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein FlxA PF14282.1 ETO20085.1 - 7.8 6.5 10.3 0.68 9.9 0.7 2.2 2 0 0 2 2 2 0 FlxA-like protein FH2 PF02181.18 ETO20086.1 - 7.7e-46 156.6 6.0 8.8e-46 156.4 4.2 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain Cytadhesin_P30 PF07271.6 ETO20086.1 - 0.059 12.6 16.0 0.099 11.9 11.1 1.3 1 0 0 1 1 1 0 Cytadhesin P30/P32 TAF PF02969.12 ETO20087.1 - 1.5e-06 28.0 0.4 1.5e-06 28.0 0.2 2.0 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) DUF3279 PF11682.3 ETO20087.1 - 0.035 13.6 1.7 0.046 13.2 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3279) Pox_A12 PF04651.8 ETO20087.1 - 0.037 14.1 5.9 0.051 13.7 4.1 1.1 1 0 0 1 1 1 0 Poxvirus A12 protein PGA2 PF07543.7 ETO20087.1 - 0.045 13.5 2.2 0.06 13.1 1.5 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 Baculo_PP31 PF05311.6 ETO20087.1 - 0.056 12.7 6.6 0.069 12.4 4.6 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) UCH_1 PF13423.1 ETO20087.1 - 0.069 12.5 6.5 0.094 12.1 4.5 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase ATP-synt_E PF05680.7 ETO20087.1 - 0.7 9.8 7.2 0.37 10.7 2.8 1.9 2 0 0 2 2 2 0 ATP synthase E chain DDHD PF02862.12 ETO20087.1 - 2.5 7.8 7.4 3 7.5 5.1 1.1 1 0 0 1 1 1 0 DDHD domain Tom37_C PF11801.3 ETO20087.1 - 3 7.6 11.0 1.9 8.3 6.0 1.7 1 1 1 2 2 2 0 Tom37 C-terminal domain PARG_cat PF05028.9 ETO20088.1 - 0.018 14.3 2.5 0.032 13.4 1.7 1.4 1 0 0 1 1 1 0 Poly (ADP-ribose) glycohydrolase (PARG) DUF751 PF05421.6 ETO20090.1 - 0.21 11.8 3.0 11 6.3 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF751) WD40 PF00400.27 ETO20091.1 - 5.9e-42 140.0 10.9 4e-12 45.5 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 ETO20091.1 - 1.3e-08 34.7 0.1 4.7e-05 23.1 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO20091.1 - 2.3e-05 22.8 0.1 0.043 12.0 0.0 2.9 1 1 2 3 3 3 3 Cytochrome D1 heme domain Nup160 PF11715.3 ETO20091.1 - 0.00044 18.5 5.5 0.24 9.4 0.3 3.6 1 1 0 2 2 2 2 Nucleoporin Nup120/160 DPPIV_N PF00930.16 ETO20091.1 - 0.0016 17.1 0.1 0.24 9.9 0.0 3.2 2 1 2 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PQQ_2 PF13360.1 ETO20091.1 - 0.0043 16.5 0.2 2.4 7.5 0.1 2.2 2 0 0 2 2 2 2 PQQ-like domain SGL PF08450.7 ETO20091.1 - 0.0059 16.0 0.1 0.26 10.6 0.1 2.3 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Nucleoporin_N PF08801.6 ETO20091.1 - 0.0079 14.9 2.7 0.67 8.6 0.2 3.3 1 1 3 4 4 4 2 Nup133 N terminal like PD40 PF07676.7 ETO20091.1 - 0.019 14.6 4.2 3.1 7.5 0.0 3.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Str_synth PF03088.11 ETO20091.1 - 0.058 13.4 0.0 0.62 10.1 0.0 2.5 2 0 0 2 2 2 0 Strictosidine synthase Proteasome_A_N PF10584.4 ETO20091.1 - 0.37 10.1 3.4 5.6 6.3 0.0 3.4 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Myosin_head PF00063.16 ETO20092.1 - 1.1e-52 179.0 2.9 1.4e-52 178.7 2.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) DUF148 PF02520.12 ETO20093.1 - 0.014 15.1 4.8 0.079 12.7 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF148 DUF1741 PF08427.5 ETO20093.1 - 0.016 14.6 0.9 0.021 14.2 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) DUF1409 PF07197.7 ETO20093.1 - 0.025 14.6 3.5 0.21 11.6 2.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1409) Osmo_CC PF08946.5 ETO20093.1 - 0.15 12.1 1.1 0.56 10.2 0.1 2.2 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Exonuc_VII_L PF02601.10 ETO20093.1 - 0.15 11.2 4.0 0.2 10.8 2.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit COG2 PF06148.6 ETO20093.1 - 0.19 11.5 2.5 0.39 10.5 1.7 1.6 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 MRP-S31 PF15433.1 ETO20094.1 - 0.026 13.9 2.4 0.029 13.8 1.7 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 SLX9 PF15341.1 ETO20094.1 - 1 9.8 15.7 1.7 9.1 10.9 1.3 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 Golgin_A5 PF09787.4 ETO20094.1 - 4.2 5.7 9.5 5.4 5.4 6.6 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 RRM_1 PF00076.17 ETO20095.1 - 1e-11 44.2 0.2 1.6e-11 43.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO20095.1 - 4.5e-05 23.3 0.0 6.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 ETO20095.1 - 0.0017 18.1 0.2 0.0027 17.5 0.2 1.4 1 0 0 1 1 1 1 RNA binding motif RRM_5 PF13893.1 ETO20095.1 - 0.0018 18.1 0.1 0.0036 17.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Gp37_Gp68 PF07505.6 ETO20095.1 - 0.077 12.1 0.0 0.077 12.1 0.0 1.1 1 0 0 1 1 1 0 Phage protein Gp37/Gp68 Telomere_reg-2 PF10193.4 ETO20096.1 - 0.086 13.1 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Telomere length regulation protein GRIP PF01465.15 ETO20097.1 - 0.0022 17.4 5.2 0.005 16.3 0.0 3.5 3 0 0 3 3 3 1 GRIP domain Fez1 PF06818.10 ETO20097.1 - 0.0024 17.9 2.2 0.0024 17.9 1.5 3.6 2 1 1 3 3 3 1 Fez1 PA26 PF04636.8 ETO20097.1 - 0.06 12.0 17.6 0.33 9.5 9.3 2.2 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) DUF3145 PF11343.3 ETO20097.1 - 0.11 11.8 0.2 0.54 9.6 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3145) Bacillus_HBL PF05791.6 ETO20097.1 - 0.67 9.3 26.5 0.13 11.5 5.3 4.0 2 1 2 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) Atg14 PF10186.4 ETO20097.1 - 0.71 8.7 35.4 0.09 11.7 0.6 2.9 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Peptidase_S10 PF00450.17 ETO20098.1 - 9.1e-33 114.0 1.4 1.1e-32 113.8 1.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase SET_assoc PF11767.3 ETO20098.1 - 0.014 14.6 0.1 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Abhydrolase_6 PF12697.2 ETO20098.1 - 0.022 14.6 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Cellulase PF00150.13 ETO20099.1 - 3.4e-16 59.2 0.0 4.5e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AAA_7 PF12775.2 ETO20100.1 - 3e-39 134.7 0.1 5.3e-39 133.9 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_8 PF12780.2 ETO20100.1 - 1e-28 100.1 0.0 1.6e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_5 PF07728.9 ETO20100.1 - 1.2e-09 38.0 0.0 3.1e-05 23.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 ETO20100.1 - 1.7e-06 28.1 0.2 0.0072 16.3 0.0 3.3 2 2 2 4 4 4 2 AAA ATPase domain DUF815 PF05673.8 ETO20100.1 - 0.00017 20.6 0.0 0.05 12.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_22 PF13401.1 ETO20100.1 - 0.00097 19.2 0.3 0.1 12.7 0.0 3.1 2 1 2 4 4 4 1 AAA domain KaiC PF06745.8 ETO20100.1 - 0.0037 16.4 0.0 0.085 11.9 0.0 2.4 2 0 0 2 2 2 1 KaiC T2SE PF00437.15 ETO20100.1 - 0.012 14.5 0.0 1.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF1528 PF07515.6 ETO20100.1 - 0.062 13.3 0.2 14 5.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1528) Sigma54_activat PF00158.21 ETO20100.1 - 0.08 12.4 0.0 0.86 9.0 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.1 ETO20100.1 - 0.15 11.4 0.0 0.81 9.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain MT PF12777.2 ETO20101.1 - 2.5e-17 62.6 8.6 3.9e-17 62.0 6.0 1.2 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.2 ETO20101.1 - 5.6e-06 25.5 1.1 1.3e-05 24.3 0.8 1.7 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 KNOX2 PF03791.8 ETO20101.1 - 0.029 13.6 0.1 0.078 12.2 0.1 1.7 1 0 0 1 1 1 0 KNOX2 domain DUF1128 PF06569.6 ETO20101.1 - 0.034 13.8 1.7 0.16 11.7 1.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) SlyX PF04102.7 ETO20101.1 - 0.071 13.4 1.7 0.21 11.9 1.1 1.8 1 0 0 1 1 1 0 SlyX Dynein_heavy PF03028.10 ETO20102.1 - 7.2e-220 731.7 1.6 1.1e-219 731.0 1.1 1.2 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_9 PF12781.2 ETO20102.1 - 3e-42 144.0 5.5 2.9e-41 140.7 2.4 2.8 2 1 0 2 2 2 1 ATP-binding dynein motor region D5 MT PF12777.2 ETO20102.1 - 5.3e-07 28.7 0.0 5.3e-07 28.7 0.0 1.6 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor KaiC PF06745.8 ETO20102.1 - 0.7 8.9 3.6 1.4 7.9 0.5 2.2 2 0 0 2 2 2 0 KaiC Merozoite_SPAM PF07133.6 ETO20105.1 - 0.00065 19.6 31.5 0.0015 18.4 21.8 1.6 1 0 0 1 1 1 1 Merozoite surface protein (SPAM) SDA1 PF05285.7 ETO20105.1 - 0.0013 18.0 22.3 0.0013 18.0 15.5 1.4 2 0 0 2 2 2 1 SDA1 Vfa1 PF08432.5 ETO20105.1 - 0.02 14.9 15.8 0.047 13.7 10.9 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 ETO20105.1 - 0.033 12.2 15.6 0.053 11.5 10.8 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF2201_N PF13203.1 ETO20105.1 - 0.048 12.8 2.9 0.083 12.0 2.0 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain ANTAR PF03861.9 ETO20105.1 - 0.082 12.5 0.4 0.33 10.5 0.0 2.1 2 0 0 2 2 2 0 ANTAR domain Zip PF02535.17 ETO20105.1 - 0.19 10.6 3.4 0.31 10.0 2.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Mem_trans PF03547.13 ETO20105.1 - 0.2 9.8 1.0 0.26 9.5 0.7 1.3 1 0 0 1 1 1 0 Membrane transport protein SAPS PF04499.10 ETO20105.1 - 0.31 9.6 17.1 2.7 6.5 8.6 2.4 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein HSP90 PF00183.13 ETO20105.1 - 0.35 9.2 23.7 0.72 8.1 16.4 1.4 1 0 0 1 1 1 0 Hsp90 protein DUF1510 PF07423.6 ETO20105.1 - 0.49 9.7 25.4 0.88 8.8 17.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Autophagy_N PF03986.8 ETO20105.1 - 0.88 9.3 16.0 2.1 8.1 11.1 1.6 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain CobT PF06213.7 ETO20105.1 - 1 8.4 23.8 1.5 7.8 16.5 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TFIIF_alpha PF05793.7 ETO20105.1 - 1.4 7.2 30.7 2 6.7 21.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Daxx PF03344.10 ETO20105.1 - 4.4 5.6 29.9 6.4 5.1 20.7 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 ETO20105.1 - 5.4 4.8 34.6 8 4.2 24.0 1.1 1 0 0 1 1 1 0 Nop14-like family Sec62 PF03839.11 ETO20105.1 - 9.4 5.5 12.2 20 4.4 8.4 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 VESA1_N PF12785.2 ETO20107.1 - 0.016 14.1 0.9 0.022 13.7 0.6 1.1 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 DUF1371 PF07115.6 ETO20108.1 - 0.015 15.4 0.3 0.044 13.9 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1371) Colicin_D PF11429.3 ETO20108.1 - 0.083 13.0 1.7 0.38 10.9 0.6 2.5 2 1 1 3 3 3 0 Colicin D FKBP_C PF00254.23 ETO20110.1 - 4.2e-06 26.6 0.0 9.7e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Lyase_8 PF02278.13 ETO20110.1 - 0.027 13.8 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide lyase family 8, super-sandwich domain DUF294_C PF10335.4 ETO20111.1 - 0.00018 21.1 0.0 0.00049 19.7 0.0 1.7 1 0 0 1 1 1 1 Putative nucleotidyltransferase substrate binding domain DUF678 PF05077.7 ETO20112.1 - 0.085 12.8 0.3 0.43 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF678) C_GCAxxG_C_C PF09719.5 ETO20112.1 - 0.11 12.3 0.6 0.2 11.4 0.4 1.4 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) ETRAMP PF09716.5 ETO20112.1 - 0.18 11.7 0.2 0.18 11.7 0.1 2.5 3 2 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) RP-C_C PF11800.3 ETO20113.1 - 0.095 12.3 1.2 0.11 12.2 0.8 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF745 PF05335.8 ETO20114.1 - 0.032 13.7 1.0 0.032 13.7 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Orbi_VP5 PF00901.12 ETO20114.1 - 0.065 11.4 5.0 0.083 11.0 3.5 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 FKBP_C PF00254.23 ETO20115.1 - 5e-12 45.6 0.1 1.2e-11 44.4 0.0 1.7 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Daxx PF03344.10 ETO20115.1 - 0.016 13.7 4.4 0.022 13.2 3.0 1.1 1 0 0 1 1 1 0 Daxx Family Ribosomal_60s PF00428.14 ETO20115.1 - 0.067 13.5 1.1 0.14 12.5 0.8 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DDHD PF02862.12 ETO20115.1 - 0.068 12.9 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 DDHD domain DivIC PF04977.10 ETO20116.1 - 0.0014 18.1 3.5 0.0014 18.1 2.4 2.8 1 1 1 2 2 2 1 Septum formation initiator bZIP_1 PF00170.16 ETO20116.1 - 0.0028 17.5 9.6 0.031 14.2 2.7 2.6 1 1 1 2 2 2 1 bZIP transcription factor Rootletin PF15035.1 ETO20116.1 - 0.0041 17.1 3.6 0.0067 16.4 2.5 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion TMF_TATA_bd PF12325.3 ETO20116.1 - 0.0086 15.7 6.3 0.021 14.5 4.4 1.6 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding bZIP_2 PF07716.10 ETO20116.1 - 0.028 14.2 12.3 0.49 10.2 2.9 2.6 2 0 0 2 2 2 0 Basic region leucine zipper HALZ PF02183.13 ETO20116.1 - 0.029 14.0 5.3 0.55 9.9 0.6 3.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF972 PF06156.8 ETO20116.1 - 0.034 14.4 4.5 0.12 12.6 3.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Nnf1 PF03980.9 ETO20116.1 - 0.071 13.1 6.5 0.61 10.1 0.3 2.7 2 0 0 2 2 2 0 Nnf1 IncA PF04156.9 ETO20116.1 - 0.16 11.5 4.8 0.27 10.8 3.3 1.3 1 0 0 1 1 1 0 IncA protein Fib_alpha PF08702.5 ETO20116.1 - 0.23 11.5 4.0 0.52 10.4 2.8 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Atg14 PF10186.4 ETO20116.1 - 0.33 9.8 4.9 0.56 9.1 3.4 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Kinetocho_Slk19 PF12709.2 ETO20116.1 - 0.41 10.7 6.3 0.45 10.6 3.2 1.9 1 1 1 2 2 2 0 Central kinetochore-associated TSC22 PF01166.13 ETO20116.1 - 0.94 9.4 12.7 0.6 10.1 2.4 2.9 2 1 1 3 3 3 0 TSC-22/dip/bun family DUF2570 PF10828.3 ETO20116.1 - 1.5 8.4 7.6 3.5 7.2 5.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DUF904 PF06005.7 ETO20116.1 - 2 8.7 13.7 35 4.7 9.5 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF904) FlaC_arch PF05377.6 ETO20116.1 - 2.1 8.3 7.3 3.2 7.7 0.7 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Herpes_BLRF2 PF05812.7 ETO20116.1 - 2.6 7.9 9.8 2.2 8.1 0.8 2.5 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein FlxA PF14282.1 ETO20116.1 - 5.8 6.9 11.3 0.19 11.6 3.3 1.9 2 0 0 2 2 1 0 FlxA-like protein UPF0449 PF15136.1 ETO20116.1 - 6.2 7.0 7.5 57 4.0 2.8 3.0 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF1129 PF06570.6 ETO20117.1 - 0.0059 15.9 0.1 0.011 15.1 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1129) PT PF04886.7 ETO20118.1 - 2.4e-104 340.2 528.8 2.5e-07 29.8 12.0 24.8 2 2 13 15 15 15 10 PT repeat CAP_GLY PF01302.20 ETO20120.1 - 1.5e-23 82.2 5.2 1.3e-15 56.8 0.6 2.6 2 0 0 2 2 2 2 CAP-Gly domain Ribosomal_L14 PF00238.14 ETO20120.1 - 0.012 15.3 4.0 0.16 11.7 2.3 2.4 2 0 0 2 2 2 0 Ribosomal protein L14p/L23e DUF1295 PF06966.7 ETO20122.1 - 1.4e-14 54.0 0.1 3.3e-14 52.7 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 ETO20122.1 - 1.7e-05 24.6 0.2 4e-05 23.4 0.1 1.6 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 ETO20122.1 - 0.0056 16.7 1.5 0.01 15.9 0.2 2.1 2 1 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 ETO20122.1 - 0.033 14.3 0.0 0.074 13.2 0.0 1.6 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family NDK PF00334.14 ETO20123.1 - 1.6e-23 82.9 0.0 3.8e-11 42.9 0.0 2.7 2 1 0 2 2 2 2 Nucleoside diphosphate kinase Fork_head PF00250.13 ETO20124.1 - 0.086 12.8 4.7 0.3 11.1 0.5 2.7 1 1 2 3 3 3 0 Fork head domain DUF489 PF04356.7 ETO20124.1 - 0.17 11.4 9.5 0.32 10.5 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF489) IFT57 PF10498.4 ETO20124.1 - 0.18 10.5 23.6 0.37 9.4 7.2 2.4 2 1 0 2 2 2 0 Intra-flagellar transport protein 57 DUF1664 PF07889.7 ETO20124.1 - 0.32 10.7 13.9 0.14 11.9 2.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Sec3_C_2 PF15278.1 ETO20124.1 - 1.3 9.2 7.8 0.22 11.6 0.3 3.1 3 2 1 4 4 4 0 Sec3 exocyst complex subunit NPV_P10 PF05531.7 ETO20124.1 - 4.2 7.7 12.2 10 6.4 2.6 3.4 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF972 PF06156.8 ETO20124.1 - 4.3 7.7 21.5 7 7.0 2.1 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Laminin_II PF06009.7 ETO20124.1 - 5.2 6.8 18.2 0.054 13.2 3.3 2.8 3 1 1 4 4 4 0 Laminin Domain II His_kinase PF06580.8 ETO20124.1 - 6.4 6.7 7.8 2.7 7.9 0.8 3.2 2 1 2 4 4 4 0 Histidine kinase PolyA_pol PF01743.15 ETO20125.1 - 1.1e-06 28.8 0.1 5.4e-05 23.3 0.0 2.6 1 1 1 2 2 2 2 Poly A polymerase head domain Ribosomal_L1 PF00687.16 ETO20126.1 - 1.8e-21 76.5 0.1 3.2e-21 75.6 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family Amidase_6 PF12671.2 ETO20127.1 - 0.00036 20.6 0.1 0.00063 19.8 0.0 1.4 1 0 0 1 1 1 1 Putative amidase domain DAGK_acc PF00609.14 ETO20128.1 - 2.9e-30 105.5 0.0 6.1e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 ETO20128.1 - 2.8e-17 62.3 0.0 6e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Senescence_reg PF04520.8 ETO20128.1 - 2.2 8.7 10.8 0.33 11.4 1.7 3.1 3 0 0 3 3 3 0 Senescence regulator Yippee-Mis18 PF03226.9 ETO20129.1 - 9e-16 57.7 5.3 9e-16 57.7 3.7 2.6 2 1 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TFIIA PF03153.8 ETO20129.1 - 0.00014 21.8 22.9 0.00021 21.3 15.9 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Chorion_2 PF03964.10 ETO20129.1 - 0.002 18.6 0.2 0.0042 17.5 0.2 1.5 1 0 0 1 1 1 1 Chorion family 2 Daxx PF03344.10 ETO20129.1 - 1.7 7.0 54.8 0.19 10.1 19.2 2.0 2 0 0 2 2 2 0 Daxx Family PP2C PF00481.16 ETO20130.1 - 0.0029 17.0 5.1 0.076 12.3 0.1 2.5 2 1 1 3 3 3 2 Protein phosphatase 2C TFIIF_alpha PF05793.7 ETO20131.1 - 0.073 11.4 33.0 0.089 11.1 22.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF605 PF04652.11 ETO20131.1 - 0.09 12.1 27.4 0.12 11.7 19.0 1.3 1 0 0 1 1 1 0 Vta1 like Macoilin PF09726.4 ETO20131.1 - 1.2 7.2 17.3 1.2 7.3 12.0 1.1 1 0 0 1 1 1 0 Transmembrane protein KIAA1328 PF15369.1 ETO20131.1 - 1.2 8.8 11.5 1.8 8.3 8.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 DUF566 PF04484.7 ETO20131.1 - 2.1 7.7 16.6 3.1 7.2 11.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF4551 PF15087.1 ETO20131.1 - 7.5 4.7 15.0 11 4.2 10.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF1387 PF07139.6 ETO20134.1 - 0.091 12.3 5.1 0.063 12.8 0.9 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1387) Apolipoprotein PF01442.13 ETO20134.1 - 0.12 11.8 7.4 0.18 11.3 5.1 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 ETO20134.1 - 0.77 9.5 4.3 2 8.2 2.1 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SSFA2_C PF14723.1 ETO20134.1 - 1.3 8.6 4.5 32 4.2 2.7 2.6 2 1 0 2 2 2 0 Sperm-specific antigen 2 C-terminus PARG_cat PF05028.9 ETO20135.1 - 6.3e-13 48.6 0.1 7.7e-13 48.3 0.1 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) Cir_N PF10197.4 ETO20136.1 - 5.6e-05 23.0 12.0 5.6e-05 23.0 8.3 5.4 5 1 0 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR zf-CCHC PF00098.18 ETO20136.1 - 0.025 14.4 1.6 0.055 13.4 1.1 1.6 1 0 0 1 1 1 0 Zinc knuckle Kelch_6 PF13964.1 ETO20137.1 - 8e-07 28.9 10.3 0.0048 17.0 0.2 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 ETO20137.1 - 9.3e-07 28.3 5.4 0.00041 20.0 0.1 4.6 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.1 ETO20137.1 - 1.3e-06 28.0 1.4 0.0092 15.7 0.1 3.9 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO20137.1 - 0.0029 17.1 12.5 0.17 11.4 0.3 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 ETO20137.1 - 0.017 15.0 1.0 0.017 15.0 0.7 4.6 6 0 0 6 6 6 0 Kelch motif Peptidase_M23 PF01551.17 ETO20139.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M23 Paf1 PF03985.8 ETO20140.1 - 0.046 12.4 0.0 0.046 12.4 0.0 1.2 1 0 0 1 1 1 0 Paf1 DUF4149 PF13664.1 ETO20141.1 - 0.62 10.1 17.1 1.8 8.6 3.4 3.8 2 2 1 3 3 3 0 Domain of unknown function (DUF4149) Kelch_4 PF13418.1 ETO20142.1 - 2.9e-07 30.1 0.0 0.0063 16.2 0.0 3.1 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO20142.1 - 6.8e-06 26.0 0.8 0.00068 19.7 0.1 3.7 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.10 ETO20142.1 - 2.1e-05 24.1 0.6 0.0037 16.9 0.1 4.1 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.20 ETO20142.1 - 0.00037 19.9 6.1 0.0018 17.7 0.1 3.9 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.1 ETO20142.1 - 0.0025 17.9 0.0 0.02 15.0 0.0 2.6 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO20142.1 - 0.0087 16.0 2.5 8 6.5 0.1 5.0 6 0 0 6 6 6 1 Kelch motif Peptidase_C14 PF00656.17 ETO20143.1 - 5.4e-10 39.3 0.8 8.5e-10 38.7 0.6 1.4 1 0 0 1 1 1 1 Caspase domain Clr2 PF10383.4 ETO20143.1 - 0.85 9.6 3.7 3.9 7.4 0.1 3.2 3 0 0 3 3 3 0 Transcription-silencing protein Clr2 HEAT_2 PF13646.1 ETO20144.1 - 3.9e-18 65.5 0.0 0.00016 21.8 0.0 6.8 1 1 9 10 10 10 6 HEAT repeats NACHT PF05729.7 ETO20144.1 - 1.5e-14 54.0 0.0 1.9e-13 50.3 0.0 3.0 2 1 0 2 2 2 1 NACHT domain HEAT PF02985.17 ETO20144.1 - 3.1e-13 48.6 0.8 0.16 12.1 0.0 9.2 10 0 0 10 10 9 2 HEAT repeat HEAT_EZ PF13513.1 ETO20144.1 - 1.6e-07 31.5 1.7 0.48 10.9 0.0 7.6 5 3 3 8 8 8 2 HEAT-like repeat Ank_4 PF13637.1 ETO20144.1 - 1.3e-06 28.7 0.6 4.2e-06 27.1 0.1 2.2 2 0 0 2 2 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO20144.1 - 6.4e-05 23.2 2.3 0.0003 21.0 0.0 3.4 4 1 0 4 4 4 1 Ankyrin repeats (3 copies) AAA_22 PF13401.1 ETO20144.1 - 0.0004 20.5 0.5 0.11 12.5 0.0 4.4 3 0 0 3 3 3 1 AAA domain Ank_5 PF13857.1 ETO20144.1 - 0.00091 19.4 0.1 0.0093 16.1 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 ETO20144.1 - 0.00095 18.8 0.0 0.0039 16.9 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.1 ETO20144.1 - 0.0011 18.9 0.1 0.036 14.3 0.0 3.5 2 0 0 2 2 2 1 Ankyrin repeat AAA_16 PF13191.1 ETO20144.1 - 0.0012 18.8 0.0 0.42 10.5 0.0 3.9 3 1 1 4 4 4 1 AAA ATPase domain PBP1_TM PF14812.1 ETO20147.1 - 0.00019 21.6 13.9 0.00037 20.7 9.6 1.5 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.9 ETO20147.1 - 0.013 13.6 7.5 0.014 13.4 5.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.8 ETO20147.1 - 0.27 8.9 11.8 0.35 8.5 8.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi FLO_LFY PF01698.11 ETO20147.1 - 0.67 8.7 9.4 0.86 8.3 6.5 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein RNA_pol_Rpc4 PF05132.9 ETO20147.1 - 1.4 8.8 9.5 1.4 8.9 2.5 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 TRAP_alpha PF03896.11 ETO20147.1 - 4.7 6.1 9.1 1.3 7.9 4.0 1.6 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Sigma70_ner PF04546.8 ETO20147.1 - 6.7 6.2 15.7 0.9 9.1 8.2 1.5 2 0 0 2 2 2 0 Sigma-70, non-essential region Circo_capsid PF02443.10 ETO20148.1 - 0.36 10.1 6.1 0.16 11.2 2.2 1.8 2 0 0 2 2 2 0 Circovirus capsid protein Guanylate_cyc PF00211.15 ETO20149.1 - 4e-05 23.0 0.0 0.076 12.3 0.0 2.2 1 1 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain CTP_transf_1 PF01148.15 ETO20150.1 - 3.7e-08 33.3 5.4 6e-08 32.6 3.7 1.3 1 0 0 1 1 1 1 Cytidylyltransferase family Aminotran_3 PF00202.16 ETO20152.1 - 6.7e-19 67.9 0.0 9.7e-19 67.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III ALS_ss_C PF10369.4 ETO20152.1 - 0.077 12.7 0.0 15 5.4 0.0 2.5 2 0 0 2 2 2 0 Small subunit of acetolactate synthase DUF4467 PF14729.1 ETO20152.1 - 0.085 13.1 0.4 0.21 11.9 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function with cystatin-like fold (DUF4467) KAP_NTPase PF07693.9 ETO20153.1 - 3.7e-38 131.3 0.2 5.3e-37 127.5 0.1 2.1 1 1 0 1 1 1 1 KAP family P-loop domain AAA_22 PF13401.1 ETO20153.1 - 0.00019 21.5 0.1 0.017 15.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain Elong_Iki1 PF10483.4 ETO20153.1 - 0.017 14.4 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 IIGP PF05049.8 ETO20153.1 - 0.025 13.4 0.0 0.058 12.1 0.0 1.5 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) COG2 PF06148.6 ETO20154.1 - 0.09 12.6 0.0 0.09 12.6 0.0 1.7 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 SH PF01445.12 ETO20155.1 - 0.0061 16.1 3.4 0.0061 16.1 1.2 1.8 1 1 1 2 2 2 1 Viral small hydrophobic protein AgrB PF04647.10 ETO20155.1 - 0.2 10.7 4.6 0.32 10.0 3.2 1.3 1 0 0 1 1 1 0 Accessory gene regulator B TatC PF00902.13 ETO20155.1 - 0.2 11.0 3.8 0.48 9.7 2.6 1.6 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) RhoGEF PF00621.15 ETO20156.1 - 2.1e-29 102.6 7.8 6.8e-27 94.5 4.1 3.6 2 1 0 2 2 2 1 RhoGEF domain WD40 PF00400.27 ETO20157.1 - 1e-05 25.1 1.9 12 5.9 0.0 6.3 6 1 0 6 6 6 3 WD domain, G-beta repeat Glyco_transf_10 PF00852.14 ETO20158.1 - 2.5e-19 69.0 0.0 3.9e-19 68.4 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) Glyco_transf_10 PF00852.14 ETO20159.1 - 2e-32 112.1 3.5 2.2e-32 112.0 2.4 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) CSD PF00313.17 ETO20160.1 - 0.001 18.7 0.0 0.068 12.9 0.0 3.2 3 0 0 3 3 3 1 'Cold-shock' DNA-binding domain DUF2775 PF10950.3 ETO20160.1 - 0.075 13.2 0.2 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2775) ENTH PF01417.15 ETO20162.1 - 0.00022 21.0 1.1 0.0013 18.5 0.1 2.1 2 0 0 2 2 2 1 ENTH domain DUF3021 PF11457.3 ETO20162.1 - 0.023 14.5 2.1 0.023 14.5 1.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) EphA2_TM PF14575.1 ETO20162.1 - 0.046 14.1 0.2 0.16 12.4 0.2 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Sarcoglycan_2 PF05510.8 ETO20162.1 - 0.091 11.0 0.4 0.13 10.5 0.3 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Herpes_UL92 PF03048.9 ETO20162.1 - 0.1 12.1 5.4 0.14 11.7 3.7 1.2 1 0 0 1 1 1 0 UL92 family YajC PF02699.10 ETO20162.1 - 0.34 10.6 14.5 0.88 9.2 0.7 2.7 2 1 1 3 3 3 0 Preprotein translocase subunit DUF2393 PF09624.5 ETO20162.1 - 2.5 7.6 9.2 0.34 10.4 3.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) AAA_16 PF13191.1 ETO20163.1 - 1.9e-06 27.9 0.0 3.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 ETO20163.1 - 2.5e-06 27.3 0.4 1.3e-05 24.9 0.3 2.2 1 1 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 ETO20163.1 - 4.1e-06 26.5 0.0 9.7e-06 25.3 0.0 1.7 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 ETO20163.1 - 0.00014 20.8 1.1 0.00023 20.1 0.8 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 ETO20163.1 - 0.00029 21.0 0.2 0.00084 19.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain P22_AR_C PF10548.4 ETO20163.1 - 0.029 14.2 0.3 0.1 12.4 0.2 1.9 1 0 0 1 1 1 0 P22AR C-terminal domain DUF258 PF03193.11 ETO20163.1 - 0.04 13.1 0.0 0.085 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Phospholip_A2_2 PF05826.7 ETO20163.1 - 0.051 13.5 0.9 0.11 12.4 0.6 1.5 1 0 0 1 1 1 0 Phospholipase A2 Miro PF08477.8 ETO20163.1 - 0.06 13.8 0.3 0.27 11.7 0.0 2.3 2 1 0 2 2 2 0 Miro-like protein HapK PF11639.3 ETO20163.1 - 0.12 12.9 0.5 0.4 11.3 0.1 2.0 2 0 0 2 2 2 0 REDY-like protein HapK AAA_14 PF13173.1 ETO20163.1 - 0.21 11.5 2.3 0.28 11.0 0.3 2.2 2 1 0 2 2 2 0 AAA domain MAPEG PF01124.13 ETO20164.1 - 3e-08 33.3 0.4 4e-08 32.9 0.3 1.1 1 0 0 1 1 1 1 MAPEG family COX15-CtaA PF02628.10 ETO20164.1 - 0.025 13.4 0.6 0.036 12.9 0.3 1.4 1 1 0 1 1 1 0 Cytochrome oxidase assembly protein PAP2_3 PF14378.1 ETO20164.1 - 0.03 13.8 0.1 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 PAP2 superfamily DUF3040 PF11239.3 ETO20164.1 - 0.64 10.1 3.4 1.6 8.8 0.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3040) PUB PF09409.5 ETO20165.1 - 0.017 14.8 0.3 0.017 14.8 0.2 2.9 2 0 0 2 2 2 0 PUB domain MFS_1 PF07690.11 ETO20167.1 - 6.4e-11 41.5 5.9 5.8e-08 31.8 5.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 ETO20167.1 - 5e-06 26.2 0.8 5e-06 26.2 0.6 2.7 2 0 0 2 2 2 1 MFS_1 like family ATG22 PF11700.3 ETO20167.1 - 2.2e-05 23.1 0.1 0.00013 20.6 0.1 2.1 1 1 1 2 2 2 1 Vacuole effluxer Atg22 like EphA2_TM PF14575.1 ETO20167.1 - 0.00051 20.3 1.4 8.2 6.8 0.2 4.1 3 1 0 3 3 3 2 Ephrin type-A receptor 2 transmembrane domain LacY_symp PF01306.14 ETO20167.1 - 0.0024 16.4 0.0 0.0024 16.4 0.0 2.1 2 0 0 2 2 2 1 LacY proton/sugar symporter SF-assemblin PF06705.6 ETO20168.1 - 6.6e-24 84.4 31.1 8.5e-24 84.0 21.6 1.1 1 0 0 1 1 1 1 SF-assemblin/beta giardin Filament PF00038.16 ETO20168.1 - 0.0022 17.5 32.7 0.41 10.0 10.7 3.4 1 1 2 3 3 3 3 Intermediate filament protein Allexi_40kDa PF05549.6 ETO20168.1 - 0.0088 15.3 3.6 0.0088 15.3 2.5 2.8 1 1 2 3 3 3 1 Allexivirus 40kDa protein RRF_GI PF12614.3 ETO20168.1 - 0.023 14.5 15.2 0.16 11.7 3.7 2.7 1 1 2 3 3 3 0 Ribosome recycling factor AAA_13 PF13166.1 ETO20168.1 - 0.033 12.6 32.7 0.015 13.8 15.6 2.0 1 1 1 2 2 2 0 AAA domain Baculo_PEP_C PF04513.7 ETO20168.1 - 0.088 12.6 10.7 0.49 10.2 0.2 3.2 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus MbeD_MobD PF04899.7 ETO20168.1 - 0.092 12.6 7.2 2.8 7.8 1.5 4.0 2 1 1 3 3 3 0 MbeD/MobD like LPP PF04728.8 ETO20168.1 - 0.093 12.5 0.5 0.95 9.3 0.0 2.8 3 0 0 3 3 3 0 Lipoprotein leucine-zipper DUF3584 PF12128.3 ETO20168.1 - 0.1 9.9 30.5 0.24 8.6 20.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) NFRKB_winged PF14465.1 ETO20168.1 - 0.16 11.8 2.2 0.43 10.4 0.1 2.5 2 1 0 2 2 2 0 NFRKB Winged Helix-like DUF1664 PF07889.7 ETO20168.1 - 0.26 11.0 23.1 0.42 10.4 1.7 4.1 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) Mt_ATP-synt_D PF05873.7 ETO20168.1 - 0.81 9.3 13.0 0.26 10.9 5.6 2.4 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) NPV_P10 PF05531.7 ETO20168.1 - 0.98 9.7 9.0 0.42 10.9 0.3 3.7 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein IMS_C PF11799.3 ETO20168.1 - 1.1 9.1 5.1 15 5.5 3.5 2.6 1 1 0 1 1 1 0 impB/mucB/samB family C-terminal domain DASH_Dam1 PF08653.5 ETO20168.1 - 3.7 7.3 5.5 6.1 6.6 0.2 3.2 3 0 0 3 3 3 0 DASH complex subunit Dam1 DUF4239 PF14023.1 ETO20168.1 - 7.3 5.8 9.8 0.89 8.8 1.9 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF4239) GEMIN8 PF15348.1 ETO20169.1 - 0.034 14.1 1.1 0.046 13.7 0.8 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DUF4512 PF14975.1 ETO20169.1 - 0.4 11.5 2.8 1.3 9.9 1.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4512) RPEL PF02755.10 ETO20171.1 - 0.00063 18.9 2.0 0.0012 18.0 1.4 1.5 1 0 0 1 1 1 1 RPEL repeat KOG2701 PF09762.4 ETO20172.1 - 0.052 13.6 3.7 0.066 13.2 0.2 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein (DUF2037) MBT PF02820.13 ETO20172.1 - 0.092 12.6 0.1 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 mbt repeat SPC25 PF06703.6 ETO20173.1 - 0.3 10.6 1.8 9.9 5.7 0.1 2.4 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) RRM_1 PF00076.17 ETO20174.1 - 6e-15 54.6 0.1 1e-14 53.8 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO20174.1 - 8.2e-10 38.5 0.0 1.7e-09 37.5 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO20174.1 - 7.4e-08 32.1 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Gly-zipper_OmpA PF13436.1 ETO20175.1 - 0.00034 20.2 10.9 0.00034 20.2 7.6 3.2 3 0 0 3 3 3 1 Glycine-zipper containing OmpA-like membrane domain Sporozoite_P67 PF05642.6 ETO20175.1 - 0.0012 16.8 21.1 0.0012 16.8 14.6 4.5 1 1 4 5 5 5 1 Sporozoite P67 surface antigen Ras PF00071.17 ETO20176.1 - 4.2e-07 29.4 0.1 7.7e-07 28.6 0.1 1.5 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.22 ETO20176.1 - 0.0017 17.8 0.4 0.0028 17.0 0.3 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF3593 PF12159.3 ETO20177.1 - 0.34 10.7 0.1 0.34 10.7 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3593) Ndc1_Nup PF09531.5 ETO20178.1 - 0.0091 14.4 0.2 0.011 14.2 0.1 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Pkinase PF00069.20 ETO20179.1 - 7.5e-43 146.5 3.2 2.5e-40 138.2 0.0 3.5 2 2 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO20179.1 - 1.6e-17 63.4 6.2 2e-12 46.7 0.0 2.8 3 1 1 4 4 4 2 Protein tyrosine kinase APH PF01636.18 ETO20179.1 - 0.00092 19.0 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 ETO20179.1 - 0.003 16.9 0.0 0.0067 15.7 0.0 1.6 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 ETO20179.1 - 0.0046 16.0 0.0 0.0082 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETO20179.1 - 0.029 13.3 0.0 0.042 12.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.6 ETO20179.1 - 0.046 12.5 0.0 0.085 11.6 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 SurA_N PF09312.6 ETO20180.1 - 0.0053 16.5 0.2 0.014 15.2 0.1 1.7 1 0 0 1 1 1 1 SurA N-terminal domain DUF4164 PF13747.1 ETO20180.1 - 1.7 8.8 6.0 17 5.5 0.5 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) Pam16 PF03656.8 ETO20181.1 - 2.6e-17 62.8 3.2 3.5e-17 62.3 2.2 1.2 1 0 0 1 1 1 1 Pam16 DehI PF10778.4 ETO20181.1 - 0.027 13.9 0.1 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 Halocarboxylic acid dehydrogenase DehI DUF1423 PF07227.6 ETO20181.1 - 0.096 11.3 2.5 0.12 11.0 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) DUF3007 PF11460.3 ETO20181.1 - 0.28 11.2 1.5 0.38 10.8 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3007) Pex14_N PF04695.8 ETO20181.1 - 3.9 7.5 8.8 3.6 7.6 5.5 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-C3HC4_3 PF13920.1 ETO20182.1 - 5.3e-06 25.9 8.0 5.3e-06 25.9 5.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.11 ETO20182.1 - 5.5e-06 26.1 0.2 5.5e-06 26.1 0.1 2.2 2 0 0 2 2 2 1 Seven in absentia protein family zf-TRAF PF02176.13 ETO20182.1 - 6.9e-06 26.3 2.9 6.9e-06 26.3 2.0 2.5 1 1 1 2 2 1 1 TRAF-type zinc finger DUF1644 PF07800.7 ETO20182.1 - 6.1e-05 22.9 11.7 0.0088 15.9 6.5 3.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1644) zf-C3HC4 PF00097.20 ETO20182.1 - 7.8e-05 22.2 12.8 7.8e-05 22.2 8.9 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO20182.1 - 9.6e-05 22.1 9.8 9.6e-05 22.1 6.8 2.5 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO20182.1 - 0.00027 20.9 11.6 0.00027 20.9 8.0 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-H2C2_5 PF13909.1 ETO20182.1 - 0.0021 18.2 0.3 0.0021 18.2 0.2 3.3 3 0 0 3 3 3 1 C2H2-type zinc-finger domain DUF4494 PF14902.1 ETO20182.1 - 0.018 14.6 0.1 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4494) zf-RING_5 PF14634.1 ETO20182.1 - 0.019 14.7 9.9 0.019 14.7 6.9 2.6 2 1 0 2 2 2 0 zinc-RING finger domain zf-RING_6 PF14835.1 ETO20182.1 - 0.11 12.2 5.0 0.28 11.0 3.5 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein GAGA PF09237.6 ETO20182.1 - 0.14 11.7 8.6 0.28 10.8 0.7 3.2 2 1 1 3 3 3 0 GAGA factor zf-C3HC4_4 PF15227.1 ETO20182.1 - 2.6 8.0 16.4 1.4 8.8 9.4 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING EF-hand_8 PF13833.1 ETO20183.1 - 0.026 14.1 2.6 0.19 11.3 0.1 3.2 3 1 1 4 4 4 0 EF-hand domain pair EF-hand_1 PF00036.27 ETO20183.1 - 0.17 11.2 0.6 1.8 8.0 0.0 2.5 3 0 0 3 3 3 0 EF hand DUF1779 PF08680.5 ETO20184.1 - 0.035 13.9 1.5 0.036 13.9 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1779) m04gp34like PF12216.3 ETO20184.1 - 0.078 12.3 3.5 0.08 12.2 2.4 1.1 1 0 0 1 1 1 0 Immune evasion protein DUF3287 PF11690.3 ETO20184.1 - 2.7 8.1 5.5 3.6 7.6 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) DUF3959 PF13105.1 ETO20184.1 - 5.7 6.1 8.8 6.8 5.9 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Exo_endo_phos PF03372.18 ETO20185.1 - 3.2e-07 30.5 0.0 4.1e-07 30.2 0.0 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Glycos_transf_1 PF00534.15 ETO20185.1 - 0.052 12.9 0.5 0.075 12.4 0.3 1.2 1 0 0 1 1 1 0 Glycosyl transferases group 1 Pribosyltran_N PF13793.1 ETO20186.1 - 3e-35 120.4 0.0 2e-34 117.7 0.0 2.0 1 1 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Glutaredoxin PF00462.19 ETO20189.1 - 1.1e-16 60.5 0.2 2.1e-16 59.6 0.0 1.6 2 0 0 2 2 2 1 Glutaredoxin ETRAMP PF09716.5 ETO20191.1 - 0.069 13.1 5.0 0.17 11.8 3.5 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF1049 PF06305.6 ETO20192.1 - 6 6.4 6.2 4.2 6.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) G-alpha PF00503.15 ETO20193.1 - 0.0071 15.0 0.4 0.0071 15.0 0.3 2.2 2 0 0 2 2 2 1 G-protein alpha subunit SnAPC_2_like PF11035.3 ETO20195.1 - 0.14 11.5 0.3 0.25 10.7 0.2 1.3 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2-like Pkinase_Tyr PF07714.12 ETO20196.1 - 5.2e-44 150.2 0.6 2.7e-30 105.3 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 ETO20196.1 - 2.9e-38 131.5 0.5 5.1e-29 101.2 0.1 2.5 2 0 0 2 2 2 2 Protein kinase domain Mem_trans PF03547.13 ETO20196.1 - 0.079 11.2 0.0 0.12 10.6 0.0 1.3 1 0 0 1 1 1 0 Membrane transport protein 14-3-3 PF00244.15 ETO20197.1 - 2e-06 27.0 0.7 5.6e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 14-3-3 protein Spore_GerAC PF05504.6 ETO20197.1 - 0.17 11.6 4.5 0.28 10.9 3.1 1.2 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal TT_ORF2 PF02957.10 ETO20198.1 - 0.072 13.8 1.2 0.19 12.4 0.8 1.7 1 0 0 1 1 1 0 TT viral ORF2 Kinesin PF00225.18 ETO20199.1 - 1.8e-61 207.6 1.1 3.2e-60 203.5 0.8 2.3 1 1 0 1 1 1 1 Kinesin motor domain Far-17a_AIG1 PF04750.9 ETO20199.1 - 0.057 12.5 0.0 0.58 9.2 0.0 2.3 2 0 0 2 2 2 0 FAR-17a/AIG1-like protein Cortex-I_coil PF09304.5 ETO20200.1 - 0.0096 15.9 9.6 0.0096 15.9 6.6 4.8 2 1 4 6 6 6 1 Cortexillin I, coiled coil ADIP PF11559.3 ETO20200.1 - 0.014 15.3 18.2 0.014 15.3 12.6 4.5 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding DUF771 PF05595.6 ETO20200.1 - 5.9 6.8 9.4 1.4 8.9 0.9 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF771) E1-E2_ATPase PF00122.15 ETO20202.1 - 5.2e-54 182.7 0.0 8.9e-54 181.9 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 ETO20202.1 - 5.2e-28 97.7 1.5 5.7e-17 61.8 0.1 3.1 4 0 0 4 4 4 2 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 ETO20202.1 - 2.5e-16 59.3 0.3 5.3e-16 58.3 0.2 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 ETO20202.1 - 5.1e-16 59.7 0.1 4.2e-10 40.3 0.0 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETO20202.1 - 1.2e-05 25.5 0.0 0.1 12.7 0.0 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 ETO20202.1 - 5.9e-05 22.4 0.0 0.00016 21.0 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus ubiquitin PF00240.18 ETO20202.1 - 0.00015 21.1 0.0 0.00032 20.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Hydrolase_3 PF08282.7 ETO20202.1 - 0.001 18.7 1.4 0.001 18.7 1.0 2.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase PABP PF00658.13 ETO20203.1 - 4.5e-08 32.6 0.0 7.1e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain SRC-1 PF08832.5 ETO20203.1 - 0.0083 16.8 0.5 0.0083 16.8 0.3 2.3 2 0 0 2 2 2 1 Steroid receptor coactivator TSP9 PF11493.3 ETO20203.1 - 0.16 12.5 0.3 0.35 11.4 0.2 1.6 1 1 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 DUF3446 PF11928.3 ETO20203.1 - 4.6 7.5 15.2 8.1 6.7 2.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) InvH PF04741.7 ETO20203.1 - 9.7 6.0 11.1 38 4.0 6.3 2.0 1 1 1 2 2 2 0 InvH outer membrane lipoprotein RRM_1 PF00076.17 ETO20204.1 - 2e-14 52.9 0.4 4.1e-06 26.3 0.1 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO20204.1 - 7.3e-12 45.0 1.0 4e-05 23.5 0.1 3.3 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO20204.1 - 5.7e-07 29.2 1.8 0.25 11.2 0.0 3.8 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETO20204.1 - 0.075 12.8 0.0 0.78 9.5 0.0 2.4 2 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Cep57_CLD_2 PF14197.1 ETO20205.1 - 0.0039 17.1 1.8 0.009 15.9 1.2 1.6 1 1 0 1 1 1 1 Centrosome localisation domain of PPC89 Erp_C PF06780.6 ETO20205.1 - 0.0093 15.8 0.9 0.012 15.4 0.6 1.1 1 0 0 1 1 1 1 Erp protein C-terminus HR1 PF02185.11 ETO20205.1 - 0.029 14.1 2.1 0.33 10.7 1.5 2.3 1 1 1 2 2 2 0 Hr1 repeat DUF4201 PF13870.1 ETO20205.1 - 0.032 13.6 2.9 0.043 13.2 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Tropomyosin_1 PF12718.2 ETO20205.1 - 0.045 13.5 2.9 0.059 13.2 2.0 1.1 1 0 0 1 1 1 0 Tropomyosin like Spc7 PF08317.6 ETO20205.1 - 0.054 12.1 2.4 0.062 11.9 1.7 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Med4 PF10018.4 ETO20205.1 - 0.069 12.5 3.1 0.086 12.2 2.0 1.3 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Allexi_40kDa PF05549.6 ETO20205.1 - 0.075 12.3 0.6 0.094 11.9 0.4 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF607 PF04678.8 ETO20205.1 - 0.1 12.5 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF607 CENP-Q PF13094.1 ETO20205.1 - 0.11 12.4 2.7 0.14 12.1 1.9 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit FlxA PF14282.1 ETO20205.1 - 0.13 12.1 1.5 0.18 11.7 1.0 1.3 1 0 0 1 1 1 0 FlxA-like protein Methyltransf_14 PF08484.6 ETO20205.1 - 0.14 11.7 0.8 0.17 11.4 0.6 1.1 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain Mnd1 PF03962.10 ETO20205.1 - 0.2 11.3 3.5 0.24 11.0 2.4 1.1 1 0 0 1 1 1 0 Mnd1 family Kelch_4 PF13418.1 ETO20206.1 - 3.4e-08 33.1 0.1 0.0042 16.8 0.0 3.5 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO20206.1 - 3e-05 24.0 0.0 0.004 17.2 0.0 2.5 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO20206.1 - 0.00017 21.0 0.1 0.003 17.0 0.0 2.8 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 ETO20206.1 - 0.00032 20.7 0.1 0.026 14.7 0.0 2.8 1 1 1 2 2 2 1 Kelch motif ThiS-like PF14453.1 ETO20211.1 - 0.098 12.5 0.9 0.21 11.4 0.1 1.9 2 0 0 2 2 2 0 ThiS-like ubiquitin NACHT PF05729.7 ETO20213.1 - 5.8e-08 32.5 0.0 1.4e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETO20213.1 - 2.7e-05 24.3 0.0 0.00027 21.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.15 ETO20213.1 - 3e-05 22.8 3.0 3e-05 22.8 2.1 2.7 3 0 0 3 3 3 2 G-protein alpha subunit AAA_18 PF13238.1 ETO20213.1 - 7.9e-05 22.9 1.7 0.0018 18.6 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ETO20213.1 - 0.00035 21.3 2.3 0.0051 17.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 ETO20213.1 - 0.0013 18.8 0.1 0.0077 16.3 0.0 2.5 1 1 0 1 1 1 1 RNA helicase UPF0079 PF02367.12 ETO20213.1 - 0.0061 16.1 0.0 0.019 14.5 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 ATP_bind_2 PF03668.10 ETO20213.1 - 0.0076 15.3 0.0 0.017 14.2 0.0 1.6 1 0 0 1 1 1 1 P-loop ATPase protein family Sigma54_activat PF00158.21 ETO20213.1 - 0.025 14.0 0.0 0.062 12.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain T2SE PF00437.15 ETO20213.1 - 0.029 13.2 0.0 0.079 11.8 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.24 ETO20213.1 - 0.032 14.4 0.0 0.087 13.0 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETO20213.1 - 0.037 13.9 0.2 0.95 9.4 0.0 2.6 1 1 0 2 2 2 0 AAA ATPase domain KaiC PF06745.8 ETO20213.1 - 0.042 12.9 0.9 1.9 7.5 0.0 3.1 3 0 0 3 3 3 0 KaiC FCP1_C PF09309.5 ETO20213.1 - 0.3 10.3 8.7 0.1 11.8 3.7 1.9 2 0 0 2 2 2 0 FCP1, C-terminal OmpH PF03938.9 ETO20213.1 - 2 8.3 17.1 0.21 11.5 4.6 3.4 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Glu-tRNAGln PF02686.10 ETO20214.1 - 0.056 13.2 2.8 0.06 13.1 0.1 2.4 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit UPF0565 PF10561.4 ETO20214.1 - 7.4 5.3 14.1 0.23 10.3 4.2 2.1 1 1 1 2 2 2 0 Uncharacterised protein family UPF0565 Cpn60_TCP1 PF00118.19 ETO20215.1 - 1e-20 73.8 0.0 1.1e-20 73.7 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MobB PF03205.9 ETO20217.1 - 0.012 15.2 0.1 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 ETO20217.1 - 0.034 13.8 6.1 0.04 13.5 0.0 3.1 3 1 0 3 3 3 0 Archaeal ATPase DUSP PF06337.7 ETO20217.1 - 0.21 12.0 5.7 0.56 10.6 1.0 2.8 2 0 0 2 2 2 0 DUSP domain EF-hand_1 PF00036.27 ETO20218.1 - 1.5e-17 61.5 7.4 0.00099 18.2 0.0 4.7 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 ETO20218.1 - 1.2e-16 60.5 6.8 3.7e-08 33.3 0.5 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 ETO20218.1 - 1.8e-13 49.1 7.8 0.00028 20.0 0.0 4.6 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 ETO20218.1 - 2.1e-13 48.8 7.0 0.0039 16.9 0.0 4.9 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 ETO20218.1 - 2.2e-07 30.3 10.2 0.85 9.2 0.0 4.9 4 1 1 5 5 5 4 EF-hand domain pair Zip PF02535.17 ETO20220.1 - 2.8 6.8 3.6 6.4 5.6 2.5 1.5 1 1 0 1 1 1 0 ZIP Zinc transporter Pex14_N PF04695.8 ETO20220.1 - 4.1 7.4 11.1 14 5.7 7.0 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RabGAP-TBC PF00566.13 ETO20221.1 - 3.8e-36 124.5 13.9 1e-29 103.5 5.7 2.8 2 1 0 2 2 2 2 Rab-GTPase-TBC domain Chromo PF00385.19 ETO20222.1 - 3e-13 49.2 5.1 1.2e-06 28.0 0.5 2.9 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain SDA1 PF05285.7 ETO20222.1 - 5.9e-05 22.5 23.6 7.9e-05 22.0 16.4 1.2 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.9 ETO20222.1 - 0.0041 15.2 18.5 0.0052 14.8 12.8 1.3 1 0 0 1 1 1 1 CDC45-like protein Mus7 PF09462.5 ETO20222.1 - 0.032 13.0 3.9 0.048 12.5 2.7 1.3 1 0 0 1 1 1 0 Mus7/MMS22 family AAA_21 PF13304.1 ETO20222.1 - 2.5 8.0 12.5 4.3 7.2 8.4 1.6 1 1 0 1 1 1 0 AAA domain Viral_Beta_CD PF04530.7 ETO20224.1 - 0.035 14.2 0.4 0.076 13.1 0.3 1.5 1 0 0 1 1 1 0 Viral Beta C/D like family Fumerase_C PF05683.7 ETO20224.1 - 0.089 11.9 0.8 0.14 11.3 0.1 1.6 2 0 0 2 2 2 0 Fumarase C-terminus MaoC_dehydratas PF01575.14 ETO20225.1 - 7.2e-14 51.2 0.0 1e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain Peptidase_C48 PF02902.14 ETO20226.1 - 1.2e-28 100.1 4.8 1.7e-28 99.7 3.3 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MetW PF07021.7 ETO20227.1 - 0.048 13.0 0.3 0.35 10.2 0.2 2.1 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW SR-25 PF10500.4 ETO20229.1 - 0.0053 16.2 12.4 0.0078 15.7 8.6 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SprA-related PF12118.3 ETO20229.1 - 0.025 13.9 8.1 0.033 13.5 5.6 1.1 1 0 0 1 1 1 0 SprA-related family RR_TM4-6 PF06459.7 ETO20229.1 - 0.053 13.4 13.1 0.079 12.8 9.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.3 ETO20229.1 - 0.12 11.1 14.9 0.15 10.7 10.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DDHD PF02862.12 ETO20229.1 - 0.16 11.7 4.7 0.24 11.1 3.2 1.3 1 0 0 1 1 1 0 DDHD domain HsdM_N PF12161.3 ETO20229.1 - 0.32 11.4 7.7 0.74 10.2 5.0 1.8 1 1 0 1 1 1 0 HsdM N-terminal domain MIP-T3 PF10243.4 ETO20229.1 - 0.4 9.0 22.5 0.55 8.6 15.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Sec62 PF03839.11 ETO20229.1 - 2.1 7.6 16.2 3.3 7.0 11.2 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DUF1510 PF07423.6 ETO20229.1 - 5.5 6.3 19.0 9.3 5.5 13.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) ATP-synt_E PF05680.7 ETO20229.1 - 8.6 6.3 14.6 1.6 8.7 7.4 1.8 2 0 0 2 2 2 0 ATP synthase E chain CDC45 PF02724.9 ETO20229.1 - 9.7 4.0 10.2 13 3.7 7.1 1.1 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.27 ETO20230.1 - 1.5e-73 240.2 22.4 2.6e-11 42.9 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Proteasome_A_N PF10584.4 ETO20230.1 - 3.6e-07 29.3 4.4 0.63 9.4 0.1 6.0 6 0 0 6 6 6 3 Proteasome subunit A N-terminal signature PQQ_2 PF13360.1 ETO20230.1 - 9.2e-07 28.5 0.6 0.00018 21.0 0.2 2.7 1 1 1 2 2 2 2 PQQ-like domain Cytochrom_D1 PF02239.11 ETO20230.1 - 3.3e-06 25.6 0.5 0.1 10.8 0.0 3.9 1 1 2 4 4 4 2 Cytochrome D1 heme domain Nup160 PF11715.3 ETO20230.1 - 4.9e-05 21.6 8.1 0.036 12.2 0.2 3.9 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 ETO20230.1 - 8.3e-05 21.5 2.0 0.12 11.1 0.2 3.7 1 1 3 4 4 4 2 Coatomer WD associated region DPPIV_N PF00930.16 ETO20230.1 - 0.0018 16.9 0.0 1.8 7.0 0.0 3.4 2 1 0 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.7 ETO20230.1 - 0.0035 16.9 9.8 5.3 6.8 0.0 5.4 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO20230.1 - 0.026 13.2 9.1 1.3 7.6 1.7 3.7 1 1 1 3 3 3 0 Nup133 N terminal like RGS PF00615.14 ETO20231.1 - 1e-07 32.0 7.6 2.7e-06 27.4 5.3 2.4 1 1 0 1 1 1 1 Regulator of G protein signaling domain Pkinase PF00069.20 ETO20233.1 - 2.5e-56 190.7 0.0 3.1e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO20233.1 - 6e-28 97.6 0.1 3.4e-27 95.1 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kelch_4 PF13418.1 ETO20233.1 - 1.9e-05 24.3 0.1 3.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Galactose oxidase, central domain Kinase-like PF14531.1 ETO20233.1 - 0.00096 18.1 0.0 0.0017 17.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kelch_3 PF13415.1 ETO20233.1 - 0.004 17.2 0.0 0.12 12.5 0.0 2.6 2 0 0 2 2 2 1 Galactose oxidase, central domain YrbL-PhoP_reg PF10707.4 ETO20233.1 - 0.0068 15.7 0.5 0.53 9.6 0.0 2.6 3 0 0 3 3 3 1 PhoP regulatory network protein YrbL Kelch_1 PF01344.20 ETO20233.1 - 0.075 12.5 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Kelch motif TT_ORF1 PF02956.9 ETO20234.1 - 8.7 4.6 15.6 11 4.3 10.8 1.3 1 0 0 1 1 1 0 TT viral orf 1 PX PF00787.19 ETO20235.1 - 1e-16 60.7 4.7 4.1e-14 52.3 1.7 2.5 2 0 0 2 2 2 2 PX domain Daxx PF03344.10 ETO20235.1 - 0.093 11.2 12.1 0.15 10.5 8.4 1.2 1 0 0 1 1 1 0 Daxx Family Methyltransf_12 PF08242.7 ETO20235.1 - 7 7.1 6.5 1.3 9.5 1.1 2.3 2 0 0 2 2 2 0 Methyltransferase domain ABC_tran PF00005.22 ETO20236.1 - 1.3e-34 119.4 0.1 9.3e-22 77.8 0.0 2.7 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 ETO20236.1 - 5.3e-14 51.8 3.8 5.3e-14 51.8 2.6 1.8 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 ETO20236.1 - 5.7e-13 49.4 0.8 0.0017 18.4 0.1 3.3 3 0 0 3 3 3 3 AAA domain SMC_N PF02463.14 ETO20236.1 - 5.7e-09 35.5 0.1 0.0038 16.4 0.0 3.2 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 ETO20236.1 - 0.00018 21.3 2.4 0.046 13.6 0.2 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 ETO20236.1 - 0.0013 17.9 3.5 4.6 6.1 0.0 3.7 4 0 0 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 ETO20236.1 - 0.0015 19.3 0.4 0.0086 16.8 0.0 2.5 3 1 0 3 3 3 1 AAA domain NACHT PF05729.7 ETO20236.1 - 0.0037 16.9 0.0 0.0094 15.6 0.0 1.7 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.1 ETO20236.1 - 0.0042 16.5 0.1 0.024 14.1 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain Miro PF08477.8 ETO20236.1 - 0.0049 17.3 0.1 0.061 13.8 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 ETO20236.1 - 0.01 15.0 0.0 0.03 13.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 ETO20236.1 - 0.011 15.5 0.0 0.028 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 ETO20236.1 - 0.014 15.7 2.8 7.3 6.8 0.2 3.1 3 0 0 3 3 3 0 AAA domain ArgK PF03308.11 ETO20236.1 - 0.017 13.9 0.2 0.048 12.4 0.0 1.7 2 0 0 2 2 2 0 ArgK protein Fez1 PF06818.10 ETO20236.1 - 0.022 14.8 3.8 0.063 13.3 2.6 1.9 1 1 0 1 1 1 0 Fez1 DUF1426 PF07234.6 ETO20236.1 - 0.046 13.4 0.9 0.11 12.2 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1426) AAA_16 PF13191.1 ETO20236.1 - 0.053 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 ETO20236.1 - 0.087 13.0 0.2 0.7 10.1 0.0 2.7 3 0 0 3 3 3 0 RNA helicase Rax2 PF12768.2 ETO20236.1 - 0.087 12.0 0.7 0.17 11.0 0.5 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity IncA PF04156.9 ETO20236.1 - 0.14 11.7 7.5 0.16 11.5 0.9 2.4 2 0 0 2 2 2 0 IncA protein DUF4446 PF14584.1 ETO20236.1 - 0.69 9.7 7.0 4.8 6.9 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF948 PF06103.6 ETO20236.1 - 5.4 6.9 9.8 1.3 8.9 0.7 3.0 4 0 0 4 4 3 0 Bacterial protein of unknown function (DUF948) Arm PF00514.18 ETO20237.1 - 5.7e-18 64.0 7.6 1.3e-05 24.7 0.0 7.5 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 ETO20237.1 - 1e-07 32.2 0.0 0.0086 16.5 0.0 4.7 4 1 1 5 5 5 3 HEAT-like repeat HEAT_2 PF13646.1 ETO20237.1 - 2.1e-06 27.9 0.0 0.2 11.9 0.0 3.3 2 2 1 3 3 3 3 HEAT repeats RICTOR_V PF14668.1 ETO20237.1 - 0.0068 16.3 5.3 0.053 13.4 0.2 4.0 3 2 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.3 ETO20237.1 - 0.02 14.8 0.9 9 6.2 0.0 3.5 3 0 0 3 3 3 0 V-ATPase subunit H DUF4474 PF14751.1 ETO20239.1 - 0.033 13.3 0.3 0.08 12.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4474) Ank_2 PF12796.2 ETO20239.1 - 0.11 12.7 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_2 PF12796.2 ETO20240.1 - 0.04 14.2 0.2 0.16 12.3 0.1 1.8 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Mga PF05043.8 ETO20240.1 - 0.086 13.1 0.7 0.19 12.0 0.5 1.6 1 0 0 1 1 1 0 Mga helix-turn-helix domain SCRL PF06876.7 ETO20240.1 - 0.6 10.1 0.1 0.6 10.1 0.1 2.4 3 0 0 3 3 3 0 Plant self-incompatibility response (SCRL) protein BUD22 PF09073.5 ETO20241.1 - 0.14 11.1 44.1 0.17 10.9 30.6 1.0 1 0 0 1 1 1 0 BUD22 MIP-T3 PF10243.4 ETO20241.1 - 3.3 6.0 52.1 3.9 5.8 36.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1777 PF08648.7 ETO20241.1 - 5.1 6.7 37.2 6.4 6.4 25.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Vfa1 PF08432.5 ETO20242.1 - 0.52 10.3 18.3 0.69 9.9 12.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Daxx PF03344.10 ETO20242.1 - 0.97 7.8 11.8 1.1 7.6 8.2 1.1 1 0 0 1 1 1 0 Daxx Family NPR3 PF03666.8 ETO20242.1 - 2.7 6.4 11.1 3.4 6.1 7.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MIP-T3 PF10243.4 ETO20242.1 - 3.2 6.1 19.2 3.6 5.9 13.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 UPF0233 PF06781.7 ETO20242.1 - 9 5.9 8.6 0.66 9.6 0.4 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) Sec62 PF03839.11 ETO20242.1 - 9.3 5.5 13.3 14 5.0 9.2 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 SICA_C PF12879.2 ETO20243.1 - 0.043 13.6 0.1 0.094 12.5 0.1 1.5 1 1 0 1 1 1 0 SICA C-terminal inner membrane domain MutS_I PF01624.15 ETO20244.1 - 0.089 12.8 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 MutS domain I DUF948 PF06103.6 ETO20244.1 - 1.3 8.9 7.0 2.7 7.8 3.2 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) MSC PF09402.5 ETO20245.1 - 0.018 13.7 2.7 0.023 13.3 1.9 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain FAM176 PF14851.1 ETO20245.1 - 0.14 11.8 1.4 0.19 11.4 1.0 1.3 1 0 0 1 1 1 0 FAM176 family Terpene_synth PF01397.16 ETO20245.1 - 0.19 11.1 3.0 0.22 10.8 2.1 1.1 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain SopA_C PF13979.1 ETO20246.1 - 3.7 7.1 9.1 0.094 12.3 0.3 2.3 1 1 2 3 3 3 0 SopA-like catalytic domain SNARE PF05739.14 ETO20248.1 - 1.1e-14 53.8 0.8 1.1e-14 53.8 0.5 2.2 2 1 0 2 2 2 1 SNARE domain Halogen_Hydrol PF10112.4 ETO20248.1 - 0.02 14.3 0.6 0.051 12.9 0.1 1.9 1 1 1 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein MCPsignal PF00015.16 ETO20248.1 - 0.021 14.4 1.4 0.038 13.5 1.0 1.4 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Sec34 PF04136.10 ETO20248.1 - 0.025 14.3 1.1 0.049 13.3 0.8 1.5 1 0 0 1 1 1 0 Sec34-like family CHASE3 PF05227.8 ETO20248.1 - 0.047 13.3 2.1 0.051 13.2 0.5 1.7 2 0 0 2 2 2 0 CHASE3 domain COPI_C PF06957.6 ETO20248.1 - 0.05 12.1 0.4 0.066 11.7 0.3 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus ABC2_membrane_3 PF12698.2 ETO20248.1 - 0.054 12.5 0.2 0.054 12.5 0.1 1.6 2 0 0 2 2 2 0 ABC-2 family transporter protein Med2 PF11214.3 ETO20248.1 - 0.073 13.1 5.5 0.037 14.0 1.5 2.0 2 0 0 2 2 2 0 Mediator complex subunit 2 DUF4363 PF14276.1 ETO20248.1 - 0.18 11.4 7.9 0.96 9.1 3.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4363) Laminin_I PF06008.9 ETO20248.1 - 0.22 10.7 8.5 0.041 13.1 3.2 1.6 2 0 0 2 2 2 0 Laminin Domain I Glutaredoxin2_C PF04399.8 ETO20248.1 - 0.36 10.4 3.0 0.5 9.9 0.9 2.0 2 1 0 2 2 2 0 Glutaredoxin 2, C terminal domain DivIC PF04977.10 ETO20248.1 - 0.4 10.2 3.5 13 5.3 0.0 3.3 1 1 2 3 3 3 0 Septum formation initiator RasGAP_C PF03836.10 ETO20248.1 - 0.78 9.4 12.6 0.68 9.6 5.1 2.6 2 1 0 2 2 2 0 RasGAP C-terminus Spectrin PF00435.16 ETO20248.1 - 1.6 9.0 8.6 1.1 9.6 0.2 2.9 2 1 1 3 3 3 0 Spectrin repeat PMC2NT PF08066.7 ETO20248.1 - 3.4 8.0 6.0 1.7 8.9 0.3 2.5 2 1 1 3 3 3 0 PMC2NT (NUC016) domain YMF19 PF02326.10 ETO20248.1 - 5.4 7.6 8.1 3.1 8.4 2.6 2.5 2 1 0 2 2 2 0 Plant ATP synthase F0 Suf PF05843.9 ETO20249.1 - 3.4e-22 79.4 0.3 3.4e-22 79.4 0.2 2.5 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) NRDE-2 PF08424.5 ETO20250.1 - 0.0059 15.5 0.1 0.0086 14.9 0.1 1.3 1 1 0 1 1 1 1 NRDE-2, necessary for RNA interference BAR PF03114.13 ETO20250.1 - 0.011 15.3 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 0 BAR domain ATP-synt_E_2 PF08112.6 ETO20250.1 - 0.097 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 ATP synthase epsilon subunit DUF3052 PF11253.3 ETO20250.1 - 0.12 12.0 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) LMBR1 PF04791.11 ETO20252.1 - 9.9 4.6 8.1 10 4.5 5.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein PI3K_C2 PF00792.19 ETO20254.1 - 2.1e-16 59.9 0.0 2.1e-16 59.9 0.0 2.3 2 1 1 3 3 3 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.13 ETO20254.1 - 1.5e-10 40.9 0.0 4e-10 39.5 0.0 1.7 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain Pex14_N PF04695.8 ETO20254.1 - 6.6e-05 22.9 2.0 0.0001 22.3 1.4 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Zip PF02535.17 ETO20254.1 - 0.049 12.6 0.6 0.074 12.0 0.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter UPF0560 PF10577.4 ETO20254.1 - 0.084 11.1 5.9 0.11 10.7 4.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Nop25 PF09805.4 ETO20254.1 - 0.3 11.1 11.8 0.55 10.2 8.2 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Secretin_N_2 PF07655.8 ETO20254.1 - 0.71 10.3 14.1 1.2 9.5 9.8 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain CDC27 PF09507.5 ETO20255.1 - 0.05 12.8 27.1 0.071 12.3 18.8 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF4279 PF14106.1 ETO20256.1 - 0.06 13.2 0.1 2.2 8.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) PIRT PF15099.1 ETO20256.1 - 0.22 10.7 0.8 0.65 9.2 0.0 2.1 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family PPTA PF01239.17 ETO20257.1 - 4.9e-20 69.9 11.8 2e-07 30.0 0.0 5.5 5 0 0 5 5 5 4 Protein prenyltransferase alpha subunit repeat Calcyon PF06387.6 ETO20258.1 - 0.058 12.7 0.1 0.086 12.2 0.1 1.3 1 0 0 1 1 1 0 D1 dopamine receptor-interacting protein (calcyon) Ion_trans PF00520.26 ETO20259.1 - 0.078 12.2 2.2 0.12 11.5 1.5 1.2 1 0 0 1 1 1 0 Ion transport protein SPOB_ab PF14682.1 ETO20259.1 - 0.22 11.3 10.6 0.045 13.5 4.3 1.9 1 1 1 2 2 2 0 Sporulation initiation phospho-transferase B, C-terminal VIT PF08487.5 ETO20259.1 - 0.27 10.9 3.4 0.79 9.4 0.3 2.4 1 1 0 2 2 2 0 Vault protein inter-alpha-trypsin domain Caldesmon PF02029.10 ETO20260.1 - 0.063 11.6 25.8 0.57 8.5 0.0 2.1 2 0 0 2 2 2 0 Caldesmon FtsK_SpoIIIE PF01580.13 ETO20260.1 - 0.12 11.8 0.0 0.12 11.8 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family KKLCAg1 PF15204.1 ETO20260.1 - 0.31 11.1 7.1 3 7.9 0.0 3.3 4 0 0 4 4 4 0 Kita-kyushu lung cancer antigen 1 Spore_coat_CotO PF14153.1 ETO20260.1 - 0.42 10.0 20.3 0.84 9.0 1.3 2.5 2 0 0 2 2 2 0 Spore coat protein CotO PPP4R2 PF09184.6 ETO20260.1 - 6.9 6.1 38.2 0.38 10.2 13.1 2.4 2 0 0 2 2 2 0 PPP4R2 TroA PF01297.12 ETO20261.1 - 0.041 13.1 0.7 0.053 12.7 0.5 1.1 1 0 0 1 1 1 0 Periplasmic solute binding protein family LXG PF04740.7 ETO20262.1 - 0.0011 18.8 3.4 0.0013 18.6 2.3 1.0 1 0 0 1 1 1 1 LXG domain of WXG superfamily ICA69 PF04629.9 ETO20262.1 - 0.0034 17.3 1.9 0.0044 17.0 1.3 1.1 1 0 0 1 1 1 1 Islet cell autoantigen ICA69, C-terminal domain OmpH PF03938.9 ETO20262.1 - 0.016 15.1 6.8 0.02 14.8 4.7 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2203 PF09969.4 ETO20262.1 - 0.021 15.0 1.6 0.028 14.6 1.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) tRNA-synt_1e PF01406.14 ETO20262.1 - 0.04 13.0 0.4 0.046 12.8 0.3 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain SEA PF01390.15 ETO20262.1 - 0.047 13.3 2.5 0.052 13.2 0.6 1.8 1 1 1 2 2 2 0 SEA domain DUF4298 PF14131.1 ETO20262.1 - 0.047 13.5 2.6 0.073 12.9 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) ADIP PF11559.3 ETO20262.1 - 0.053 13.4 10.7 0.07 13.0 7.4 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Seryl_tRNA_N PF02403.17 ETO20262.1 - 0.065 13.2 5.4 0.091 12.7 3.7 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF365 PF04033.7 ETO20262.1 - 0.085 12.8 0.3 0.13 12.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF365) Dna2 PF08696.6 ETO20262.1 - 0.1 11.9 1.7 0.13 11.5 1.2 1.1 1 0 0 1 1 1 0 DNA replication factor Dna2 RVT_connect PF06815.8 ETO20262.1 - 0.11 12.3 1.2 0.18 11.7 0.8 1.3 1 0 0 1 1 1 0 Reverse transcriptase connection domain IncA PF04156.9 ETO20262.1 - 0.12 11.9 9.1 0.19 11.3 6.3 1.3 1 0 0 1 1 1 0 IncA protein TALPID3 PF15324.1 ETO20262.1 - 0.4 7.9 7.1 0.47 7.7 4.9 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Fzo_mitofusin PF04799.8 ETO20262.1 - 2.2 7.6 9.1 3.9 6.8 0.4 2.3 1 1 2 3 3 3 0 fzo-like conserved region Integrase_AP2 PF14657.1 ETO20264.1 - 0.14 11.9 7.1 0.32 10.8 4.9 1.5 1 0 0 1 1 1 0 AP2-like DNA-binding integrase domain zf-C2H2_jaz PF12171.3 ETO20264.1 - 0.46 10.6 0.1 0.46 10.6 0.1 2.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding DUF2756 PF10956.3 ETO20265.1 - 0.2 11.8 11.6 0.45 10.7 8.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) NST1 PF13945.1 ETO20265.1 - 6.6 6.7 23.2 0.41 10.6 2.5 2.9 2 1 1 3 3 3 0 Salt tolerance down-regulator Pico_P2A PF00947.14 ETO20266.1 - 0.23 11.2 1.4 0.76 9.5 0.3 2.2 2 0 0 2 2 2 0 Picornavirus core protein 2A WD40 PF00400.27 ETO20267.1 - 1.1e-25 88.4 8.7 1.8e-11 43.4 0.1 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO20267.1 - 0.0026 15.9 0.0 1.2 7.1 0.0 2.6 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO20267.1 - 0.017 13.9 0.7 2.9 6.5 0.0 2.6 2 1 1 3 3 3 0 Nup133 N terminal like BBS2_Mid PF14783.1 ETO20267.1 - 0.41 10.4 2.2 8 6.2 0.3 3.0 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region MIP-T3 PF10243.4 ETO20268.1 - 0.2 10.0 28.3 0.23 9.8 19.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Utp14 PF04615.8 ETO20268.1 - 0.47 8.5 26.2 0.55 8.3 18.2 1.0 1 0 0 1 1 1 0 Utp14 protein DUF4045 PF13254.1 ETO20269.1 - 0.0013 18.1 0.9 0.0015 17.8 0.1 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4045) AMP-binding PF00501.23 ETO20270.1 - 1.6e-24 86.1 0.1 2.1e-24 85.6 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETO20270.1 - 4.5e-15 56.3 0.0 6.7e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF4480 PF13715.1 ETO20270.1 - 0.05 13.6 0.1 0.16 12.0 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4480) PDEase_I PF00233.14 ETO20271.1 - 1.2e-64 218.3 0.9 1.8e-64 217.7 0.1 1.8 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Ycf1 PF05758.7 ETO20271.1 - 1.7 6.2 53.0 1.6 6.3 1.1 3.1 3 0 0 3 3 3 0 Ycf1 DUF4227 PF14004.1 ETO20271.1 - 6.5 6.6 8.9 19 5.2 1.7 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4227) uDENN PF03456.13 ETO20272.1 - 6.4e-10 38.8 1.6 1.6e-09 37.6 1.1 1.8 1 1 0 1 1 1 1 uDENN domain SR-25 PF10500.4 ETO20272.1 - 0.19 11.2 9.1 0.28 10.6 6.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Paramyxo_C PF01692.13 ETO20272.1 - 3.5 7.1 6.7 5.2 6.6 4.6 1.2 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c UCH PF00443.24 ETO20273.1 - 7.8e-24 84.2 0.0 7.8e-24 84.2 0.0 3.2 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_S24 PF00717.18 ETO20273.1 - 0.0023 17.5 0.1 8.8 6.0 0.0 3.8 3 0 0 3 3 3 2 Peptidase S24-like Skp1 PF01466.14 ETO20274.1 - 2.6e-18 65.7 0.0 5.2e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 ETO20274.1 - 0.00034 20.6 1.7 0.0008 19.4 0.1 2.3 3 0 0 3 3 3 1 Skp1 family, tetramerisation domain RasGEF PF00617.14 ETO20275.1 - 5.8e-35 120.7 0.2 9.8e-35 119.9 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain GSHPx PF00255.14 ETO20275.1 - 0.056 12.8 0.1 4.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Glutathione peroxidase AAA_5 PF07728.9 ETO20276.1 - 0.12 12.1 0.6 3.7 7.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF573 PF04504.9 ETO20276.1 - 9.7 6.5 10.2 0.31 11.3 0.9 2.8 2 2 1 3 3 3 0 Protein of unknown function, DUF573 Prok-E2_D PF14460.1 ETO20277.1 - 0.019 14.4 0.1 0.058 12.8 0.0 1.7 2 0 0 2 2 2 0 Prokaryotic E2 family D Nop14 PF04147.7 ETO20278.1 - 0.75 7.6 32.6 1.1 7.1 22.6 1.1 1 0 0 1 1 1 0 Nop14-like family KA1 PF02149.14 ETO20279.1 - 0.0038 16.6 0.0 0.0097 15.3 0.0 1.7 1 0 0 1 1 1 1 Kinase associated domain 1 DUF2680 PF10925.3 ETO20279.1 - 0.07 13.0 1.4 0.15 11.9 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) SRP-alpha_N PF04086.8 ETO20280.1 - 0.0037 16.7 4.0 0.0043 16.4 2.8 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal POX PF07526.6 ETO20281.1 - 0.21 11.7 2.0 0.36 11.0 1.4 1.3 1 0 0 1 1 1 0 Associated with HOX Peptidase_S28 PF05577.7 ETO20282.1 - 2.4e-49 168.0 6.6 5.2e-44 150.5 5.2 3.1 2 1 0 2 2 2 2 Serine carboxypeptidase S28 Peptidase_S9 PF00326.16 ETO20282.1 - 0.00077 18.7 0.0 0.0018 17.5 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 ETO20282.1 - 0.042 13.7 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 ETO20282.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_3 PF07859.8 ETO20282.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ribosomal_S11 PF00411.14 ETO20283.1 - 1.3e-21 76.8 0.1 6.4e-19 68.1 0.0 3.0 2 1 0 2 2 2 2 Ribosomal protein S11 zf-4CXXC_R1 PF10497.4 ETO20283.1 - 6.9e-06 26.1 10.2 2.6e-05 24.2 7.1 1.9 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Daxx PF03344.10 ETO20283.1 - 8.9e-05 21.1 18.9 8.9e-05 21.1 13.1 2.6 2 1 0 2 2 2 1 Daxx Family Nop14 PF04147.7 ETO20283.1 - 0.0018 16.3 26.4 0.0018 16.3 18.3 2.2 2 0 0 2 2 2 1 Nop14-like family CENP-T PF15511.1 ETO20283.1 - 2.7 7.1 25.4 0.0083 15.4 6.9 2.3 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T zf-MYND PF01753.13 ETO20284.1 - 0.00015 21.5 12.3 0.00029 20.6 8.5 1.5 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 ETO20284.1 - 5.9 6.6 10.1 16 5.2 7.0 1.8 1 1 0 1 1 1 0 HIT zinc finger CmcI PF04989.7 ETO20285.1 - 0.33 10.2 2.2 0.4 9.9 1.5 1.1 1 0 0 1 1 1 0 Cephalosporin hydroxylase DUF506 PF04720.7 ETO20285.1 - 0.78 9.3 8.7 0.93 9.0 6.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Vfa1 PF08432.5 ETO20285.1 - 0.91 9.5 20.3 1.1 9.2 14.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1510 PF07423.6 ETO20285.1 - 1.1 8.5 20.0 1.3 8.3 13.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Rtf2 PF04641.7 ETO20285.1 - 2.1 7.4 16.0 2.3 7.3 11.1 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger TRAP_alpha PF03896.11 ETO20285.1 - 2.5 7.0 7.2 2.6 6.9 5.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Ycf1 PF05758.7 ETO20285.1 - 3.2 5.3 14.7 3.5 5.2 10.2 1.0 1 0 0 1 1 1 0 Ycf1 SAPS PF04499.10 ETO20285.1 - 3.4 6.1 10.0 3.7 6.0 6.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Sporozoite_P67 PF05642.6 ETO20285.1 - 3.7 5.2 8.6 4.1 5.1 6.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Borrelia_P83 PF05262.6 ETO20285.1 - 3.9 5.6 20.1 4.4 5.4 13.9 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein MIP-T3 PF10243.4 ETO20285.1 - 4.8 5.5 24.4 5.5 5.3 16.9 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SID-1_RNA_chan PF13965.1 ETO20285.1 - 6.8 4.7 5.5 6.7 4.7 3.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RNA_pol_Rpb1_5 PF04998.12 ETO20285.1 - 6.9 5.8 8.3 7.5 5.7 5.7 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 U79_P34 PF03064.11 ETO20285.1 - 7.1 6.0 14.2 7.9 5.9 9.8 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 YqfQ PF14181.1 ETO20285.1 - 7.5 6.5 15.8 12 5.9 10.9 1.3 1 0 0 1 1 1 0 YqfQ-like protein DDHD PF02862.12 ETO20285.1 - 8.4 6.1 9.0 10 5.8 6.2 1.1 1 0 0 1 1 1 0 DDHD domain LPP PF04728.8 ETO20286.1 - 0.081 12.7 4.7 0.7 9.7 0.0 3.8 4 0 0 4 4 4 0 Lipoprotein leucine-zipper Ion_trans_2 PF07885.11 ETO20287.1 - 2e-10 40.2 11.4 1.6e-09 37.3 7.8 2.3 1 1 1 2 2 2 1 Ion channel Ion_trans PF00520.26 ETO20287.1 - 5e-07 29.1 4.3 5e-07 29.1 3.0 1.7 2 0 0 2 2 2 1 Ion transport protein DUF165 PF02592.10 ETO20287.1 - 0.021 14.9 1.9 0.59 10.2 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized ACR, YhhQ family COG1738 DUF606 PF04657.8 ETO20287.1 - 0.04 14.0 0.8 1.9 8.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF606 SecE PF00584.15 ETO20287.1 - 0.048 13.2 0.1 0.048 13.2 0.1 2.5 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex DUF2938 PF11158.3 ETO20287.1 - 0.061 12.6 3.8 0.22 10.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2938) DctQ PF04290.7 ETO20287.1 - 0.26 11.0 4.8 0.39 10.4 0.3 2.2 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component MacB_PCD PF12704.2 ETO20287.1 - 0.27 10.7 1.1 15 5.0 0.1 2.1 2 0 0 2 2 2 0 MacB-like periplasmic core domain Abi PF02517.11 ETO20287.1 - 0.63 10.2 3.0 1.7 8.8 2.0 1.8 1 1 0 1 1 1 0 CAAX protease self-immunity Ins134_P3_kin PF05770.6 ETO20288.1 - 1.7e-09 37.1 0.1 1.7e-09 37.1 0.0 1.2 1 1 0 1 1 1 1 Inositol 1, 3, 4-trisphosphate 5/6-kinase TTL PF03133.10 ETO20288.1 - 0.0031 16.4 0.0 0.0033 16.3 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family DUF575 PF04746.7 ETO20289.1 - 0.028 14.4 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF575) SbcD_C PF12320.3 ETO20289.1 - 0.19 11.7 0.9 0.42 10.6 0.6 1.5 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain DUF3439 PF11921.3 ETO20290.1 - 3.4 7.4 17.0 2.3 8.0 1.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) YjgP_YjgQ PF03739.9 ETO20291.1 - 0.02 13.6 0.3 0.02 13.6 0.2 1.5 1 1 0 2 2 2 0 Predicted permease YjgP/YjgQ family AIPR PF10592.4 ETO20291.1 - 0.33 10.2 13.6 0.43 9.8 9.5 1.1 1 0 0 1 1 1 0 AIPR protein RP-C_C PF11800.3 ETO20291.1 - 0.79 9.3 4.5 1 9.0 3.1 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Herpes_MCP PF03122.9 ETO20291.1 - 0.84 6.8 5.6 0.97 6.6 3.9 1.1 1 0 0 1 1 1 0 Herpes virus major capsid protein Atg14 PF10186.4 ETO20291.1 - 1.4 7.7 22.6 1.9 7.3 15.6 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 LicD PF04991.8 ETO20291.1 - 1.5 8.9 13.7 1.6 8.7 9.5 1.1 1 0 0 1 1 1 0 LicD family U79_P34 PF03064.11 ETO20291.1 - 3 7.3 17.3 3.6 7.0 12.0 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF123 PF01986.11 ETO20291.1 - 3.5 7.8 6.4 0.3 11.2 1.0 1.7 1 1 1 2 2 2 0 Domain of unknown function DUF123 DDHD PF02862.12 ETO20291.1 - 5.3 6.7 9.4 6.5 6.4 6.5 1.1 1 0 0 1 1 1 0 DDHD domain Band_3_cyto PF07565.8 ETO20291.1 - 5.8 6.3 8.7 7.2 6.0 6.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain YMF19 PF02326.10 ETO20291.1 - 8.3 7.0 22.7 3.9 8.0 5.4 2.4 1 1 1 2 2 2 0 Plant ATP synthase F0 DUF3639 PF12341.3 ETO20293.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3639) Methyltransf_11 PF08241.7 ETO20297.1 - 5.1e-09 36.5 0.0 7.5e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO20297.1 - 7.1e-07 28.9 0.0 1.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO20297.1 - 0.00083 19.9 0.0 0.0012 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 ETO20297.1 - 0.0016 18.0 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase N2227 PF07942.7 ETO20297.1 - 0.0039 16.1 0.1 0.006 15.5 0.1 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 ETO20297.1 - 0.0048 16.6 0.0 0.0065 16.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 ETO20297.1 - 0.0062 15.9 0.1 0.0088 15.4 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.13 ETO20297.1 - 0.013 14.6 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 ETO20297.1 - 0.014 15.8 0.0 0.024 15.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 ETO20297.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Mvb12 PF09452.5 ETO20298.1 - 0.59 10.3 4.6 0.73 10.0 0.4 2.0 1 1 1 2 2 2 0 ESCRT-I subunit Mvb12 G-alpha PF00503.15 ETO20299.1 - 3.2e-75 253.2 11.8 4.2e-75 252.8 8.2 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO20299.1 - 9.4e-10 37.9 0.1 1.9e-09 36.9 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 ETO20299.1 - 0.0093 16.4 0.5 0.018 15.5 0.1 1.7 2 0 0 2 2 2 1 Miro-like protein Nucleo_P87 PF07267.6 ETO20299.1 - 0.044 12.4 0.3 0.044 12.4 0.2 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 DUF4131 PF13567.1 ETO20300.1 - 0.043 13.2 0.1 0.069 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF2304 PF10066.4 ETO20300.1 - 0.22 11.3 4.3 0.059 13.2 0.5 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Halogen_Hydrol PF10112.4 ETO20300.1 - 0.43 9.9 3.5 0.28 10.5 0.3 1.9 1 1 1 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein SSP160 PF06933.6 ETO20302.1 - 0.45 8.4 4.4 0.69 7.8 3.0 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF912 PF06024.7 ETO20302.1 - 5.8 7.0 7.7 2.4 8.2 3.4 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) WD40 PF00400.27 ETO20303.1 - 5.2e-77 251.2 14.7 2.2e-12 46.3 0.1 7.0 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO20303.1 - 3.5e-11 43.1 0.1 0.0028 17.3 0.0 3.8 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO20303.1 - 1.8e-08 33.0 0.4 0.037 12.3 0.0 3.4 1 1 4 5 5 5 5 Cytochrome D1 heme domain Nup160 PF11715.3 ETO20303.1 - 1.6e-06 26.5 7.4 0.012 13.8 0.6 4.3 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 ETO20303.1 - 6.2e-05 21.9 0.2 0.072 11.8 0.0 2.4 1 1 0 2 2 2 2 Coatomer WD associated region DUF1258 PF06869.7 ETO20303.1 - 8.4e-05 21.7 0.6 0.37 9.8 0.0 3.7 1 1 3 4 4 4 1 Protein of unknown function (DUF1258) PD40 PF07676.7 ETO20303.1 - 0.00021 20.8 9.4 9.4 6.0 0.0 5.5 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 ETO20303.1 - 0.0003 20.0 1.3 0.13 11.3 0.0 4.0 1 1 2 5 5 5 1 Neuroblastoma-amplified sequence, N terminal DUF1513 PF07433.6 ETO20303.1 - 0.00047 19.1 0.2 0.45 9.3 0.0 3.6 1 1 2 4 4 4 1 Protein of unknown function (DUF1513) PQQ_2 PF13360.1 ETO20303.1 - 0.00049 19.6 0.5 0.0024 17.3 0.3 2.4 1 1 0 1 1 1 1 PQQ-like domain Resistin PF06954.6 ETO20303.1 - 0.0013 18.9 4.3 19 5.6 0.0 5.2 3 1 3 6 6 6 0 Resistin SusE PF14292.1 ETO20303.1 - 0.0065 16.2 0.2 2.6 7.8 0.0 3.7 4 0 0 4 4 4 1 SusE outer membrane protein Proteasome_A_N PF10584.4 ETO20303.1 - 0.06 12.6 7.2 6.8 6.1 0.0 4.4 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature IKI3 PF04762.7 ETO20303.1 - 0.065 11.0 0.1 0.83 7.3 0.0 2.0 1 1 0 2 2 2 0 IKI3 family EamA PF00892.15 ETO20304.1 - 2.2e-06 27.7 5.6 2.2e-06 27.7 3.9 2.6 3 0 0 3 3 3 1 EamA-like transporter family TPT PF03151.11 ETO20304.1 - 2.7e-05 23.8 0.1 2.7e-05 23.8 0.1 2.2 3 1 0 3 3 3 1 Triose-phosphate Transporter family EmrE PF13536.1 ETO20304.1 - 0.0028 17.8 3.7 0.0028 17.8 2.6 2.1 3 0 0 3 3 3 1 Multidrug resistance efflux transporter UAA PF08449.6 ETO20304.1 - 0.007 15.3 0.7 0.007 15.3 0.5 2.5 3 0 0 3 3 3 1 UAA transporter family DUF912 PF06024.7 ETO20304.1 - 0.27 11.3 3.0 0.98 9.5 2.1 2.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Secretin_N_2 PF07655.8 ETO20304.1 - 0.28 11.6 6.1 0.54 10.6 4.2 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Apis_Csd PF11671.3 ETO20304.1 - 3 7.6 9.0 4.6 7.0 6.3 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein Sporozoite_P67 PF05642.6 ETO20304.1 - 4.8 4.9 5.8 6.5 4.4 4.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Eapp_C PF10238.4 ETO20304.1 - 5.3 6.9 14.3 10 5.9 9.9 1.6 1 1 0 1 1 1 0 E2F-associated phosphoprotein L_HGMIC_fpl PF10242.4 ETO20305.1 - 0.24 11.4 5.0 0.069 13.1 1.2 1.8 2 0 0 2 2 2 0 Lipoma HMGIC fusion partner-like protein Polysacc_synt_3 PF13440.1 ETO20306.1 - 0.0043 16.5 1.2 0.0043 16.5 0.8 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein DUF4131 PF13567.1 ETO20306.1 - 0.46 9.8 4.6 0.3 10.4 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF2975 PF11188.3 ETO20306.1 - 1.4 8.5 6.0 0.86 9.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) DUF1469 PF07332.6 ETO20306.1 - 6.1 6.5 10.8 5 6.8 5.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Pkinase PF00069.20 ETO20307.1 - 1e-17 64.1 0.0 1.5e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO20307.1 - 3.5e-07 29.5 0.0 4.6e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 ETO20308.1 - 3e-34 118.3 2.2 3e-34 118.3 1.6 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO20308.1 - 4e-25 88.3 2.2 5e-25 88.0 1.5 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Mab-21 PF03281.9 ETO20308.1 - 0.022 13.9 0.5 0.027 13.6 0.3 1.1 1 0 0 1 1 1 0 Mab-21 protein ABC1 PF03109.11 ETO20308.1 - 0.034 14.1 0.0 0.63 10.0 0.0 2.2 1 1 1 2 2 2 0 ABC1 family Synapsin PF02078.11 ETO20308.1 - 0.094 12.8 0.1 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Synapsin, N-terminal domain Pkinase PF00069.20 ETO20309.1 - 0.01 15.0 0.3 0.028 13.5 0.0 1.8 2 0 0 2 2 2 0 Protein kinase domain YebO PF13974.1 ETO20309.1 - 5.8 6.7 6.0 2.7 7.8 2.2 1.8 2 0 0 2 2 2 0 YebO-like protein DUF4504 PF14953.1 ETO20310.1 - 0.012 14.9 0.1 0.025 13.8 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4504) HD_3 PF13023.1 ETO20311.1 - 4e-23 81.9 2.2 4.4e-23 81.8 1.6 1.0 1 0 0 1 1 1 1 HD domain HD PF01966.17 ETO20311.1 - 4e-06 26.8 0.2 4.5e-06 26.6 0.1 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.2 ETO20311.1 - 0.017 14.8 0.6 0.019 14.7 0.4 1.0 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme P22_AR_C PF10548.4 ETO20311.1 - 0.027 14.3 0.4 0.25 11.2 0.1 2.5 2 1 0 2 2 2 0 P22AR C-terminal domain AAA PF00004.24 ETO20312.1 - 2.4e-42 144.2 0.0 4.1e-42 143.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 ETO20312.1 - 1.5e-07 31.5 0.2 9.3e-07 29.0 0.0 2.4 2 0 0 2 2 2 1 FtsH Extracellular AAA_22 PF13401.1 ETO20312.1 - 7e-05 22.9 0.0 0.0036 17.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO20312.1 - 8.7e-05 23.3 0.0 0.0002 22.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 ETO20312.1 - 0.00026 20.7 0.0 0.001 18.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 ETO20312.1 - 0.001 18.8 0.4 0.009 15.7 0.3 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 ETO20312.1 - 0.0013 18.7 0.1 0.011 15.7 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 ETO20312.1 - 0.0043 16.9 0.0 0.0089 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETO20312.1 - 0.0061 16.4 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 ETO20312.1 - 0.0084 15.5 0.1 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 ETO20312.1 - 0.015 14.3 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 ETO20312.1 - 0.016 14.5 0.3 0.054 12.8 0.1 1.8 1 1 1 2 2 2 0 AAA domain TIP49 PF06068.8 ETO20312.1 - 0.017 13.8 0.0 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Zeta_toxin PF06414.7 ETO20312.1 - 0.023 13.8 0.0 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.16 ETO20312.1 - 0.03 13.4 0.2 0.073 12.2 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 ETO20312.1 - 0.044 14.0 0.0 0.097 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 ETO20312.1 - 0.075 12.9 0.0 0.62 9.9 0.0 2.3 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF22 PF01629.11 ETO20312.1 - 0.087 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF22 SR-25 PF10500.4 ETO20312.1 - 3.7 6.9 23.1 0.68 9.3 1.0 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Herpes_DNAp_acc PF04929.7 ETO20312.1 - 8.5 5.2 8.7 13 4.6 6.0 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Cation_ATPase_N PF00690.21 ETO20313.1 - 9.1e-06 25.0 0.3 3.7e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cupin_8 PF13621.1 ETO20314.1 - 3.6e-10 39.7 0.7 3.6e-10 39.7 0.5 1.5 2 0 0 2 2 2 1 Cupin-like domain Cupin_4 PF08007.7 ETO20314.1 - 0.00012 21.4 0.2 0.00019 20.7 0.1 1.4 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.1 ETO20315.1 - 2.1e-07 30.6 0.1 2.6e-07 30.4 0.1 1.1 1 0 0 1 1 1 1 Cupin-like domain Tfb4 PF03850.9 ETO20315.1 - 0.086 12.0 1.2 0.1 11.8 0.8 1.1 1 0 0 1 1 1 0 Transcription factor Tfb4 Lsm_interact PF05391.6 ETO20315.1 - 1.9 8.0 5.1 1.5 8.3 1.4 2.6 2 0 0 2 2 2 0 Lsm interaction motif Pkinase PF00069.20 ETO20317.1 - 1.3e-34 119.5 0.0 1.9e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO20317.1 - 1.2e-11 44.1 0.0 2.3e-11 43.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO20317.1 - 0.04 12.8 0.0 0.066 12.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Radial_spoke_3 PF06098.6 ETO20319.1 - 0.024 13.6 1.8 0.024 13.6 1.3 1.0 1 0 0 1 1 1 0 Radial spoke protein 3 Tho2 PF11262.3 ETO20319.1 - 0.76 8.7 3.7 0.81 8.6 2.6 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Glycos_transf_1 PF00534.15 ETO20320.1 - 8.6e-08 31.7 0.0 1.4e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF4446 PF14584.1 ETO20320.1 - 0.077 12.8 0.3 0.095 12.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) FGGY_C PF02782.11 ETO20320.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Mito_carr PF00153.22 ETO20322.1 - 9.7e-28 95.7 2.1 8.2e-13 47.8 0.1 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein Myosin_head PF00063.16 ETO20323.1 - 3e-15 55.3 0.0 3e-15 55.3 0.0 2.7 2 1 0 2 2 2 1 Myosin head (motor domain) Aldedh PF00171.17 ETO20324.1 - 1.2e-34 119.5 0.0 1.3e-34 119.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 ETO20324.1 - 7.2e-05 21.6 0.1 9.7e-05 21.2 0.1 1.2 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) ATP-synt_B PF00430.13 ETO20324.1 - 0.0067 16.2 0.8 0.012 15.4 0.6 1.3 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) FCH PF00611.18 ETO20324.1 - 0.047 13.8 1.5 0.075 13.2 1.0 1.2 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain Calreticulin PF00262.13 ETO20325.1 - 1.3e-38 132.6 12.9 1.3e-38 132.6 9.0 1.5 2 0 0 2 2 2 1 Calreticulin family D5_N PF08706.6 ETO20325.1 - 0.0072 16.4 0.1 0.013 15.6 0.1 1.4 1 0 0 1 1 1 1 D5 N terminal like DUF2201_N PF13203.1 ETO20325.1 - 0.22 10.6 1.4 0.31 10.1 1.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Tetraspannin PF00335.15 ETO20326.1 - 1.8 7.7 4.4 2.6 7.2 3.0 1.3 1 0 0 1 1 1 0 Tetraspanin family Plasmodium_Vir PF05795.6 ETO20326.1 - 9.7 5.2 20.2 65 2.5 14.0 2.0 1 1 0 1 1 1 0 Plasmodium vivax Vir protein PH PF00169.24 ETO20327.1 - 5.4e-16 58.6 1.8 1.1e-15 57.7 0.9 1.8 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 ETO20327.1 - 2e-09 37.6 5.1 2e-09 37.6 3.6 2.7 2 2 0 2 2 2 1 Pleckstrin homology domain WD40 PF00400.27 ETO20327.1 - 5e-08 32.5 0.1 1e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 WD domain, G-beta repeat PH_8 PF15409.1 ETO20327.1 - 8.7e-08 32.1 1.4 1.4e-07 31.4 1.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain Vps16_C PF04840.7 ETO20327.1 - 0.12 11.2 0.1 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Vps16, C-terminal region Mucin PF01456.12 ETO20327.1 - 0.81 9.4 21.2 1.3 8.8 14.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.6 ETO20327.1 - 8.8 4.1 16.0 12 3.7 11.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Rep_fac-A_C PF08646.5 ETO20329.1 - 9.4e-05 22.1 0.1 0.0002 21.0 0.0 1.5 1 1 0 1 1 1 1 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 ETO20329.1 - 0.16 11.8 0.8 0.48 10.3 0.5 1.9 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain RPEL PF02755.10 ETO20331.1 - 2.4e-09 36.2 0.8 0.004 16.4 0.0 3.7 3 0 0 3 3 3 2 RPEL repeat CENP-B_dimeris PF09026.5 ETO20331.1 - 0.24 11.6 16.8 0.65 10.2 11.5 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Sporozoite_P67 PF05642.6 ETO20331.1 - 0.62 7.8 8.0 0.89 7.3 5.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nucleoplasmin PF03066.10 ETO20331.1 - 0.71 9.3 20.6 0.46 9.9 12.4 2.0 2 0 0 2 2 2 0 Nucleoplasmin DUF3682 PF12446.3 ETO20331.1 - 2 8.6 10.9 4.7 7.5 7.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) MIP-T3 PF10243.4 ETO20332.1 - 0.14 10.5 34.5 0.17 10.2 23.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Aldedh PF00171.17 ETO20333.1 - 2.7e-72 243.5 0.1 2.7e-35 121.6 0.0 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family TMEM125 PF15109.1 ETO20333.1 - 0.082 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 TMEM125 protein family Peptidase_C10 PF01640.12 ETO20335.1 - 0.032 13.9 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase C10 family HPS3_N PF14761.1 ETO20335.1 - 0.049 13.0 1.0 35 3.6 0.0 3.3 2 1 1 3 3 3 0 Hermansky-Pudlak syndrome 3 TPR_12 PF13424.1 ETO20337.1 - 1.2e-25 89.2 0.9 1e-14 54.2 0.1 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO20337.1 - 1.7e-17 61.7 3.1 5.9e-06 25.6 0.0 4.6 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO20337.1 - 8.4e-17 60.5 12.4 1.5e-07 30.9 0.4 2.9 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETO20337.1 - 4.3e-16 57.7 13.1 1.5e-05 24.3 0.3 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO20337.1 - 1.8e-15 55.5 10.5 0.0026 17.5 0.1 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO20337.1 - 7.5e-15 53.5 10.0 0.00024 20.6 0.4 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat SNAP PF14938.1 ETO20337.1 - 2.9e-07 29.9 0.1 0.00045 19.4 0.0 2.2 2 0 0 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_14 PF13428.1 ETO20337.1 - 3.7e-07 30.1 0.0 5.5 7.9 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO20337.1 - 5.6e-07 29.6 2.0 0.7 10.4 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO20337.1 - 2.8e-05 23.8 0.0 1.6 8.7 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO20337.1 - 6.2e-05 23.5 1.9 29 5.5 0.0 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 ETO20337.1 - 0.00013 22.0 5.0 0.1 12.7 2.3 3.2 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 ETO20337.1 - 0.00035 20.3 0.8 0.00035 20.3 0.6 4.3 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO20337.1 - 0.0026 17.8 0.6 6.8 7.1 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat DUF3868 PF12984.2 ETO20337.1 - 0.0079 15.7 0.9 0.01 15.3 0.1 1.6 2 0 0 2 2 1 1 Domain of unknown function, B. Theta Gene description (DUF3868) DUF2225 PF09986.4 ETO20337.1 - 0.016 14.7 2.3 0.031 13.7 0.7 1.9 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.13 ETO20337.1 - 0.1 12.4 8.0 17 5.3 0.1 4.2 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Mob_Pre PF01076.14 ETO20337.1 - 0.18 11.4 1.9 17 5.0 0.0 3.0 3 0 0 3 3 3 0 Plasmid recombination enzyme SHNi-TPR PF10516.4 ETO20337.1 - 1.6 8.0 4.8 26 4.1 0.0 3.2 3 0 0 3 3 3 0 SHNi-TPR WD40 PF00400.27 ETO20338.1 - 1.8e-25 87.8 9.4 8.2e-12 44.5 0.3 3.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO20338.1 - 0.0033 15.6 3.1 0.4 8.7 0.2 2.8 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Ricin_B_lectin PF00652.17 ETO20338.1 - 0.12 12.3 3.6 7.9 6.5 0.2 2.7 1 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain Aldose_epim PF01263.15 ETO20339.1 - 1.4e-18 67.0 1.2 5.9e-13 48.5 0.2 2.1 2 0 0 2 2 2 2 Aldose 1-epimerase MATH PF00917.21 ETO20339.1 - 0.0028 17.8 0.2 0.0044 17.2 0.2 1.4 1 0 0 1 1 1 1 MATH domain DUF237 PF03072.9 ETO20339.1 - 0.064 13.1 0.4 0.064 13.1 0.3 2.1 2 0 0 2 2 2 0 MG032/MG096/MG288 family 1 DUF4163 PF13739.1 ETO20339.1 - 6.4 7.6 6.6 0.38 11.5 0.8 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4163) Sod_Fe_C PF02777.13 ETO20340.1 - 4.1e-43 145.5 1.1 5.6e-43 145.1 0.8 1.1 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Kelch_6 PF13964.1 ETO20341.1 - 3.8e-08 33.1 0.9 1.7e-05 24.7 0.1 3.0 1 1 1 2 2 2 2 Kelch motif Kelch_1 PF01344.20 ETO20341.1 - 4.7e-07 29.2 3.2 8.5e-05 22.0 0.2 3.9 4 1 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO20341.1 - 0.0007 19.3 0.2 0.097 12.4 0.0 2.8 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO20341.1 - 0.0029 17.5 3.1 0.057 13.3 0.1 3.0 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 ETO20341.1 - 0.0048 17.0 0.1 0.06 13.5 0.0 2.6 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO20341.1 - 0.0048 16.6 0.1 0.85 9.4 0.1 3.2 2 0 0 2 2 2 1 Kelch motif WD40 PF00400.27 ETO20342.1 - 6.9e-55 181.0 15.2 5.4e-14 51.4 0.2 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat PD40 PF07676.7 ETO20342.1 - 3.1e-07 29.9 2.0 0.65 9.7 0.1 5.4 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat eIF2A PF08662.6 ETO20342.1 - 4.3e-05 23.3 0.0 0.0059 16.3 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO20342.1 - 9.6e-05 20.8 0.2 0.11 10.8 0.0 2.3 2 0 0 2 2 2 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO20342.1 - 0.00024 20.6 0.0 0.00045 19.7 0.0 1.4 1 0 0 1 1 1 1 PQQ-like domain Proteasome_A_N PF10584.4 ETO20342.1 - 0.0005 19.3 0.3 1.2 8.4 0.0 3.6 4 0 0 4 4 4 2 Proteasome subunit A N-terminal signature SGL PF08450.7 ETO20342.1 - 0.032 13.6 0.1 0.24 10.7 0.1 2.3 1 1 1 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region PP2C PF00481.16 ETO20343.1 - 8.5e-33 113.8 0.0 1.9e-28 99.5 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 ETO20343.1 - 0.02 14.3 0.0 7 5.9 0.0 3.0 2 1 0 2 2 2 0 Protein phosphatase 2C PP28 PF10252.4 ETO20343.1 - 0.3 11.1 3.8 0.74 9.8 2.6 1.6 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 PBP1_TM PF14812.1 ETO20344.1 - 0.13 12.5 20.0 0.027 14.7 3.3 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF912 PF06024.7 ETO20344.1 - 5.8 7.0 8.8 7.7 6.6 0.0 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) NESP55 PF06390.7 ETO20344.1 - 7.4 5.8 8.0 2.8 7.2 0.0 2.5 3 0 0 3 3 3 0 Neuroendocrine-specific golgi protein P55 (NESP55) Nucleoplasmin PF03066.10 ETO20346.1 - 0.74 9.3 9.0 1.3 8.5 6.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 ETO20346.1 - 0.96 9.7 7.0 2.2 8.5 4.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Metallophos PF00149.23 ETO20348.1 - 2.3e-42 144.7 0.7 2.8e-42 144.4 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ESSS PF10183.4 ETO20349.1 - 0.02 15.2 0.0 0.036 14.4 0.0 1.4 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) FSA_C PF10479.4 ETO20349.1 - 0.021 12.9 0.8 0.027 12.5 0.6 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Fmp27_WPPW PF10359.4 ETO20349.1 - 0.024 13.0 1.6 0.029 12.8 1.1 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain MARCKS PF02063.12 ETO20349.1 - 0.052 13.4 0.4 0.052 13.4 0.3 1.3 2 0 0 2 2 2 0 MARCKS family MSC PF09402.5 ETO20349.1 - 0.095 11.3 1.1 0.14 10.8 0.7 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain PTPS PF01242.14 ETO20349.1 - 0.11 12.1 0.7 0.21 11.2 0.4 1.5 1 1 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase Cnd1_N PF12922.2 ETO20349.1 - 0.15 11.6 2.2 0.21 11.1 1.2 1.6 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term BatA PF07584.6 ETO20349.1 - 0.17 12.0 0.5 0.17 12.0 0.3 1.8 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal DUF793 PF05633.6 ETO20349.1 - 0.71 8.5 3.0 0.96 8.1 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF793) POP1 PF06978.6 ETO20349.1 - 1.9 8.1 5.8 4.3 6.9 4.0 1.5 1 1 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 SSP160 PF06933.6 ETO20350.1 - 0.0013 16.8 11.5 0.0013 16.7 8.0 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 Mucin PF01456.12 ETO20350.1 - 0.0014 18.4 16.3 0.0017 18.1 11.3 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein GNVR PF13807.1 ETO20350.1 - 0.055 13.2 0.5 0.094 12.4 0.3 1.4 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase DUF3439 PF11921.3 ETO20350.1 - 0.088 12.5 13.4 0.14 11.9 9.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 ETO20350.1 - 0.11 10.2 9.4 0.11 10.1 6.5 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TMEM154 PF15102.1 ETO20350.1 - 2.7 7.6 11.7 5.8 6.6 8.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family PulG PF11773.3 ETO20351.1 - 0.31 10.7 3.3 0.19 11.4 0.4 2.0 2 0 0 2 2 2 0 Type II secretory pathway pseudopilin DUF3432 PF11914.3 ETO20351.1 - 1.6 8.8 6.3 0.43 10.6 1.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3432) RdRP PF05183.7 ETO20353.1 - 2.4e-16 59.5 0.0 4.7e-16 58.6 0.0 1.3 1 1 0 1 1 1 1 RNA dependent RNA polymerase STAT_int PF02865.12 ETO20353.1 - 0.057 13.3 1.2 0.088 12.7 0.3 1.7 2 0 0 2 2 2 0 STAT protein, protein interaction domain zf-TRAF PF02176.13 ETO20354.1 - 3e-12 46.7 44.4 3.5e-07 30.4 5.0 5.5 2 1 3 6 6 5 3 TRAF-type zinc finger zf-C3HC4 PF00097.20 ETO20354.1 - 3.4e-09 36.1 11.6 3.4e-09 36.1 8.0 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO20354.1 - 4.3e-09 36.2 10.5 4.3e-09 36.2 7.3 3.5 3 1 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO20354.1 - 5.4e-07 29.1 11.3 5.4e-07 29.1 7.9 3.3 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO20354.1 - 3.8e-06 26.6 12.7 3.8e-06 26.6 8.8 3.4 2 1 0 2 2 1 1 Ring finger domain zf-RING_6 PF14835.1 ETO20354.1 - 0.00082 19.1 4.2 0.00082 19.1 2.9 2.1 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 ETO20354.1 - 0.0026 17.5 10.5 0.0026 17.5 7.3 3.2 2 1 1 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 ETO20354.1 - 0.0031 17.2 14.3 0.0031 17.2 9.9 3.7 2 2 1 3 3 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 ETO20354.1 - 0.0041 16.8 6.6 0.016 14.9 4.6 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 ETO20354.1 - 0.0059 16.0 6.8 0.0059 16.0 4.7 2.3 3 0 0 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit Sina PF03145.11 ETO20354.1 - 0.018 14.7 2.7 0.018 14.7 1.9 3.3 1 1 1 3 3 3 0 Seven in absentia protein family HhH-GPD PF00730.20 ETO20355.1 - 0.019 15.2 0.0 6.4 7.1 0.0 2.3 1 1 1 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein FAM60A PF15396.1 ETO20356.1 - 7.5 6.2 10.5 2.9 7.5 2.8 2.1 2 0 0 2 2 2 0 Protein Family FAM60A Mucin PF01456.12 ETO20357.1 - 6.1 6.6 19.7 11 5.7 13.6 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Peptidase_C14 PF00656.17 ETO20358.1 - 3.1e-11 43.4 0.6 4.9e-11 42.8 0.4 1.3 1 0 0 1 1 1 1 Caspase domain Tospo_nucleocap PF01533.11 ETO20358.1 - 0.062 12.5 1.1 1.7 7.7 0.1 2.3 2 0 0 2 2 2 0 Tospovirus nucleocapsid protein UCH PF00443.24 ETO20358.1 - 0.071 12.2 0.6 0.13 11.3 0.4 1.5 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF2783 PF10932.3 ETO20358.1 - 0.081 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2783) NPV_P10 PF05531.7 ETO20359.1 - 0.00032 20.8 9.3 0.058 13.6 2.0 2.5 3 0 0 3 3 2 2 Nucleopolyhedrovirus P10 protein NDUF_B5 PF09781.4 ETO20359.1 - 0.011 14.9 0.4 0.018 14.3 0.3 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit FlaC_arch PF05377.6 ETO20359.1 - 0.031 14.1 8.4 2.9 7.8 0.0 3.1 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) SpoIIIAH PF12685.2 ETO20359.1 - 0.05 13.0 10.3 0.08 12.4 6.8 1.4 1 1 0 1 1 1 0 SpoIIIAH-like protein DUF883 PF05957.8 ETO20359.1 - 0.07 13.5 4.4 1.8 9.0 0.5 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Baculo_PEP_C PF04513.7 ETO20359.1 - 0.098 12.4 3.9 5.1 6.9 0.4 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Effector_1 PF04518.7 ETO20359.1 - 0.16 10.8 14.6 0.2 10.5 9.1 1.7 1 1 1 2 2 2 0 Effector from type III secretion system ACCA PF03255.9 ETO20359.1 - 0.19 11.2 13.7 0.04 13.4 5.0 2.2 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Cep57_CLD PF14073.1 ETO20359.1 - 0.2 11.4 23.5 0.93 9.2 16.0 1.9 1 1 0 1 1 1 0 Centrosome localisation domain of Cep57 Fzo_mitofusin PF04799.8 ETO20359.1 - 0.22 10.8 11.7 0.043 13.2 1.5 2.3 2 0 0 2 2 2 0 fzo-like conserved region Tet_JBP PF12851.2 ETO20359.1 - 0.3 10.3 4.3 0.43 9.8 3.0 1.4 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily DUF4175 PF13779.1 ETO20359.1 - 0.3 8.7 10.5 0.43 8.2 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Peroxin-22 PF12827.2 ETO20359.1 - 0.59 9.8 7.8 1 9.0 5.4 1.4 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family DUF1664 PF07889.7 ETO20359.1 - 0.67 9.7 12.2 0.73 9.6 3.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) IncA PF04156.9 ETO20359.1 - 1.1 8.8 19.4 8.2e+02 -0.6 13.5 2.2 1 1 0 1 1 1 0 IncA protein LOH1CR12 PF10158.4 ETO20359.1 - 1.4 8.6 14.0 0.66 9.7 4.3 2.3 1 1 1 2 2 2 0 Tumour suppressor protein CorA PF01544.13 ETO20359.1 - 1.7 7.6 8.0 3.3 6.6 5.5 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4200 PF13863.1 ETO20359.1 - 3.3 7.6 25.6 63 3.5 15.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF4404 PF14357.1 ETO20359.1 - 4.8 7.6 11.8 1.2 9.6 0.4 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4404) DUF2664 PF10867.3 ETO20359.1 - 5.4 7.7 11.5 0.24 12.0 2.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2664) DASH_Spc34 PF08657.5 ETO20359.1 - 6 6.4 16.6 8 6.0 10.6 1.7 1 1 0 1 1 1 0 DASH complex subunit Spc34 Tup_N PF08581.5 ETO20359.1 - 7.8 6.7 17.8 0.24 11.6 4.8 2.6 2 1 1 3 3 3 0 Tup N-terminal SPX PF03105.14 ETO20359.1 - 8.6 6.0 14.8 33 4.1 10.2 1.7 1 1 0 1 1 1 0 SPX domain MecA_N PF05223.6 ETO20361.1 - 0.1 12.6 1.7 0.13 12.3 1.2 1.0 1 0 0 1 1 1 0 NTF2-like N-terminal transpeptidase domain DUF2870 PF11069.3 ETO20361.1 - 0.3 11.1 2.9 0.38 10.8 2.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) Sec8_exocyst PF04048.9 ETO20362.1 - 0.0004 20.0 1.4 0.0004 20.0 1.0 1.8 1 1 1 2 2 2 1 Sec8 exocyst complex component specific domain DUF3584 PF12128.3 ETO20362.1 - 0.0088 13.4 7.3 0.011 13.1 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Med9 PF07544.8 ETO20362.1 - 0.011 15.4 7.0 0.055 13.2 2.3 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 T2SF PF00482.18 ETO20362.1 - 0.012 15.5 0.3 0.021 14.7 0.2 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Hemerythrin PF01814.18 ETO20362.1 - 0.025 14.7 3.1 0.05 13.7 2.1 1.5 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain TPR_MLP1_2 PF07926.7 ETO20362.1 - 0.036 13.8 12.1 0.78 9.4 6.6 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Spectrin PF00435.16 ETO20362.1 - 0.17 12.2 9.6 0.89 9.8 4.8 2.1 2 0 0 2 2 2 0 Spectrin repeat DUF4200 PF13863.1 ETO20362.1 - 0.22 11.4 15.4 0.89 9.5 8.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) STAT_alpha PF01017.15 ETO20362.1 - 0.26 10.9 5.8 0.52 9.9 4.0 1.5 1 1 0 1 1 1 0 STAT protein, all-alpha domain Spc7 PF08317.6 ETO20362.1 - 0.3 9.7 8.2 0.41 9.2 5.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4618 PF15397.1 ETO20362.1 - 0.34 10.1 9.9 6.2 6.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Syntaxin-6_N PF09177.6 ETO20362.1 - 0.43 11.0 5.9 7.8 6.9 0.0 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Nsp1_C PF05064.8 ETO20362.1 - 0.44 10.2 6.5 11 5.7 2.9 2.5 1 1 1 2 2 2 0 Nsp1-like C-terminal region BLOC1_2 PF10046.4 ETO20362.1 - 0.5 10.5 7.4 3.9 7.6 4.9 2.4 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4140 PF13600.1 ETO20362.1 - 0.71 10.3 6.6 23 5.5 0.0 2.8 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) TBPIP PF07106.8 ETO20362.1 - 0.72 9.3 8.7 2.5 7.6 6.0 1.8 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) APG6 PF04111.7 ETO20362.1 - 1.4 7.8 10.3 1.9 7.4 7.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF919 PF06034.6 ETO20362.1 - 1.6 8.4 10.0 1.2 8.7 3.6 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) bZIP_1 PF00170.16 ETO20362.1 - 1.6 8.7 13.0 2.4 8.1 2.7 3.1 2 1 1 3 3 3 0 bZIP transcription factor DUF3552 PF12072.3 ETO20362.1 - 1.6 7.9 14.3 0.54 9.4 7.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Fib_alpha PF08702.5 ETO20362.1 - 1.6 8.8 5.9 4.4 7.4 3.9 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Prefoldin PF02996.12 ETO20362.1 - 2.1 8.0 9.6 6.6 6.4 5.2 2.2 2 0 0 2 2 2 0 Prefoldin subunit Sec2p PF06428.6 ETO20362.1 - 2.3 8.1 12.4 6.1 6.7 1.0 2.4 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p Mnd1 PF03962.10 ETO20362.1 - 4 7.0 13.0 12 5.4 8.8 1.7 1 1 0 1 1 1 0 Mnd1 family MerR-DNA-bind PF09278.6 ETO20362.1 - 5.3 7.5 6.9 21 5.6 3.4 2.4 2 0 0 2 2 2 0 MerR, DNA binding GAS PF13851.1 ETO20362.1 - 6.5 5.8 15.1 45 3.1 10.5 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding FliJ PF02050.11 ETO20362.1 - 7.1 6.7 13.7 13 5.8 9.5 1.5 1 1 0 1 1 1 0 Flagellar FliJ protein V_ATPase_I PF01496.14 ETO20362.1 - 8 4.1 9.1 16 3.1 6.3 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 ETO20362.1 - 9.3 5.7 11.6 81 2.7 8.0 2.0 1 1 0 1 1 1 0 IncA protein Med13_C PF06333.7 ETO20363.1 - 0.16 10.4 2.6 0.092 11.2 0.2 1.6 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal Sporozoite_P67 PF05642.6 ETO20364.1 - 3.8 5.2 6.4 0.8 7.4 2.0 1.5 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Radical_SAM PF04055.16 ETO20365.1 - 7e-25 88.1 0.0 1.6e-24 86.9 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 ETO20365.1 - 1.4e-24 85.9 0.1 3.5e-24 84.6 0.1 1.7 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 ETO20365.1 - 2.3e-18 66.5 0.9 7.5e-18 64.9 0.0 2.2 2 0 0 2 2 2 1 Flavodoxin CMD PF02627.15 ETO20365.1 - 0.18 11.6 1.0 1.6 8.6 0.2 2.5 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family Mcp5_PH PF12814.2 ETO20366.1 - 1.4e-05 25.0 0.2 1.4e-05 25.0 0.1 2.7 3 0 0 3 3 3 1 Meiotic cell cortex C-terminal pleckstrin homology Ank_2 PF12796.2 ETO20367.1 - 4.5e-15 55.7 2.3 2.8e-05 24.3 0.1 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO20367.1 - 5.8e-09 36.2 0.4 0.0015 19.0 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO20367.1 - 4.5e-08 32.5 2.1 0.14 12.4 0.0 5.7 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.1 ETO20367.1 - 2.7e-05 24.2 0.3 0.33 11.2 0.0 3.3 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 ETO20367.1 - 0.0032 17.2 0.9 0.62 9.9 0.1 3.2 4 0 0 4 4 4 1 Ankyrin repeat GBP_C PF02841.9 ETO20368.1 - 0.00058 19.1 2.6 0.0007 18.8 1.8 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain L27_2 PF09045.5 ETO20368.1 - 0.015 14.8 0.2 0.35 10.4 0.0 2.7 2 0 0 2 2 2 0 L27_2 DUF3376 PF11856.3 ETO20368.1 - 0.017 14.5 0.2 0.02 14.2 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3376) DUF607 PF04678.8 ETO20368.1 - 0.1 12.5 0.4 0.12 12.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF607 DUF3829 PF12889.2 ETO20368.1 - 0.1 11.7 6.1 0.05 12.7 1.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3829) CbiC PF02570.10 ETO20368.1 - 0.15 11.4 0.1 0.22 10.9 0.1 1.2 1 0 0 1 1 1 0 Precorrin-8X methylmutase DUF3552 PF12072.3 ETO20368.1 - 0.29 10.3 8.9 0.38 9.9 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Dpoe2NT PF12213.3 ETO20368.1 - 0.34 10.8 3.5 7.9 6.4 0.1 3.2 3 1 0 3 3 3 0 DNA polymerases epsilon N terminal DUF3571 PF12095.3 ETO20368.1 - 1.5 9.0 4.2 2.2 8.5 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3571) THDPS_N PF14790.1 ETO20369.1 - 0.05 13.2 0.1 0.072 12.7 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Sec7 PF01369.15 ETO20370.1 - 1.1e-36 126.2 0.4 2.6e-36 125.0 0.3 1.6 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 ETO20370.1 - 0.0013 18.9 0.1 0.0053 16.9 0.0 2.2 2 0 0 2 2 2 1 PH domain Toxin-deaminase PF14424.1 ETO20370.1 - 0.017 15.1 0.1 6.9 6.6 0.0 2.6 2 0 0 2 2 2 0 The BURPS668_1122 family of deaminases PH_11 PF15413.1 ETO20370.1 - 0.039 14.2 0.0 0.18 12.0 0.0 2.2 1 0 0 1 1 1 0 Pleckstrin homology domain Peptidase_M48 PF01435.13 ETO20370.1 - 0.071 12.6 0.0 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Peptidase family M48 TFIIA PF03153.8 ETO20371.1 - 0.019 14.8 17.3 0.046 13.6 12.0 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tom22 PF04281.8 ETO20371.1 - 1.7 8.1 15.6 1.8 8.0 0.1 2.6 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 MFS_1 PF07690.11 ETO20372.1 - 2.5e-06 26.4 12.0 2.5e-06 26.4 8.3 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily YlaC PF10777.4 ETO20372.1 - 0.026 14.1 2.3 0.026 14.1 1.6 2.3 2 0 0 2 2 2 0 Inner membrane protein YlaC Claudin_2 PF13903.1 ETO20372.1 - 1.5 8.4 11.7 8.9 5.9 6.7 2.5 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Aminotran_1_2 PF00155.16 ETO20373.1 - 8.5e-21 74.2 0.0 1e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II LacI PF00356.16 ETO20373.1 - 0.033 13.7 0.2 0.074 12.6 0.2 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family OKR_DC_1 PF01276.15 ETO20373.1 - 0.05 12.1 0.0 0.15 10.5 0.0 1.7 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Myotub-related PF06602.9 ETO20374.1 - 4e-24 85.0 0.0 9.1e-24 83.8 0.0 1.5 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain C2 PF00168.25 ETO20374.1 - 3.9e-11 42.6 0.3 1.2e-10 41.0 0.2 1.9 1 0 0 1 1 1 1 C2 domain C9orf72-like PF15019.1 ETO20375.1 - 9.5e-23 80.6 1.6 1.9e-19 69.8 0.1 2.4 2 0 0 2 2 2 2 C9orf72-like protein family Neur_chan_memb PF02932.11 ETO20375.1 - 5.1 6.9 15.1 1.5 8.6 0.9 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region zf-RanBP PF00641.13 ETO20377.1 - 0.0025 16.9 0.6 0.0025 16.9 0.4 1.9 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others DUF3279 PF11682.3 ETO20377.1 - 0.0085 15.6 0.5 0.021 14.3 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3279) Cript PF10235.4 ETO20377.1 - 0.019 15.2 0.2 0.019 15.2 0.2 2.4 2 1 0 2 2 2 0 Microtubule-associated protein CRIPT XAP5 PF04921.9 ETO20377.1 - 0.026 14.0 13.6 0.034 13.7 9.4 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator DZR PF12773.2 ETO20377.1 - 0.078 12.8 0.5 0.17 11.6 0.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon GCC2_GCC3 PF07699.8 ETO20377.1 - 0.084 12.4 0.7 0.084 12.4 0.5 1.9 2 0 0 2 2 2 0 GCC2 and GCC3 Secretin_N_2 PF07655.8 ETO20377.1 - 0.19 12.1 12.1 0.39 11.1 8.4 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain CDC45 PF02724.9 ETO20377.1 - 1.2 7.1 12.4 1.4 6.8 8.6 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-C2H2 PF00096.21 ETO20378.1 - 0.0032 17.7 1.0 0.0032 17.7 0.7 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 ETO20378.1 - 0.0045 16.8 0.8 0.0045 16.8 0.6 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-BED PF02892.10 ETO20378.1 - 0.061 13.0 11.7 0.051 13.3 2.9 2.5 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_4 PF13894.1 ETO20378.1 - 0.13 12.6 0.3 0.13 12.6 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETO20378.1 - 0.5 10.7 15.4 0.098 12.9 1.9 3.0 3 0 0 3 3 3 0 Zinc-finger double domain RSN1_TM PF13967.1 ETO20379.1 - 0.0012 18.4 1.7 0.0025 17.3 0.6 1.8 1 1 1 2 2 2 1 Late exocytosis, associated with Golgi transport Sarcoglycan_2 PF05510.8 ETO20379.1 - 0.018 13.3 0.2 0.021 13.1 0.1 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon BatD PF13584.1 ETO20379.1 - 0.019 13.6 4.4 0.013 14.1 2.1 1.3 1 1 0 1 1 1 0 Oxygen tolerance DUF2500 PF10694.4 ETO20379.1 - 0.036 14.0 1.9 0.094 12.7 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) OATP PF03137.15 ETO20379.1 - 0.037 12.0 3.2 0.051 11.6 2.2 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_S49_N PF08496.5 ETO20379.1 - 3.5 7.3 10.5 0.45 10.2 4.1 1.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF3139 PF11337.3 ETO20379.1 - 9.5 6.5 10.4 7.4 6.9 4.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3139) GATase PF00117.23 ETO20380.1 - 1.7e-11 43.8 0.0 2.6e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 ETO20380.1 - 0.00021 20.8 0.0 0.00031 20.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.9 ETO20380.1 - 0.11 12.0 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Mg296 PF09644.5 ETO20381.1 - 0.0021 17.8 2.7 0.0037 17.1 1.8 1.6 1 1 0 1 1 1 1 Mg296 protein GCHY-1 PF02649.9 ETO20381.1 - 0.0045 16.2 1.1 0.0055 15.9 0.8 1.0 1 0 0 1 1 1 1 Type I GTP cyclohydrolase folE2 SPOB_ab PF14682.1 ETO20381.1 - 0.026 14.2 1.0 0.047 13.4 0.7 1.3 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal DUF1091 PF06477.8 ETO20381.1 - 0.053 13.9 0.4 0.093 13.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1091) Pkinase PF00069.20 ETO20381.1 - 0.096 11.8 5.4 0.08 12.0 2.9 1.5 2 0 0 2 2 2 0 Protein kinase domain CENP-Q PF13094.1 ETO20381.1 - 0.98 9.4 7.1 1.1 9.2 0.2 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit HDAC4_Gln PF12203.3 ETO20381.1 - 2.1 8.3 8.4 0.095 12.6 0.6 2.2 1 1 1 2 2 2 0 Glutamine rich N terminal domain of histone deacetylase 4 SR-25 PF10500.4 ETO20381.1 - 2.9 7.3 16.1 1.6 8.1 0.8 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Ydc2-catalyt PF09159.5 ETO20381.1 - 4.9 6.5 9.8 6.3 6.1 6.8 1.2 1 0 0 1 1 1 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Protocadherin PF08374.6 ETO20381.1 - 6.4 6.3 14.9 5.4 6.5 0.5 2.1 1 1 1 2 2 2 0 Protocadherin VPS9 PF02204.13 ETO20382.1 - 4.9e-09 36.1 0.0 7.2e-07 29.1 0.0 2.6 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain YMF19 PF02326.10 ETO20382.1 - 0.071 13.6 12.9 0.69 10.5 1.2 2.9 3 0 0 3 3 3 0 Plant ATP synthase F0 Glyco_hydro_35 PF01301.14 ETO20383.1 - 8.4e-28 97.6 0.0 1.1e-27 97.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Ras PF00071.17 ETO20385.1 - 8.9e-17 60.9 0.1 2.3e-08 33.5 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 ETO20385.1 - 0.0035 17.8 0.1 0.0091 16.4 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein CENP-S PF15630.1 ETO20386.1 - 5.9e-13 48.8 0.9 1.7e-12 47.3 0.1 2.0 2 0 0 2 2 2 1 Kinetochore component CENP-S TFIID_20kDa PF03847.8 ETO20386.1 - 0.1 12.9 1.9 1.4 9.2 1.3 2.4 1 1 0 1 1 1 0 Transcription initiation factor TFIID subunit A CENP-B_dimeris PF09026.5 ETO20386.1 - 3.1 8.1 6.5 3.8 7.7 2.2 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Solute_trans_a PF03619.11 ETO20387.1 - 1.3e-35 123.0 14.1 1.5e-35 122.8 9.8 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Solute_trans_a PF03619.11 ETO20388.1 - 2.7e-22 79.3 9.5 6.8e-22 78.0 6.6 1.7 1 1 0 1 1 1 1 Organic solute transporter Ostalpha IMD PF08397.6 ETO20388.1 - 0.035 13.4 0.6 0.064 12.5 0.4 1.3 1 0 0 1 1 1 0 IRSp53/MIM homology domain Pepsin-I3 PF06394.8 ETO20389.1 - 0.0015 18.1 1.1 0.0095 15.5 0.7 2.4 1 0 0 1 1 1 1 Pepsin inhibitor-3-like repeated domain Band_7_1 PF13421.1 ETO20390.1 - 0.0059 16.1 0.7 0.0079 15.7 0.5 1.1 1 0 0 1 1 1 1 SPFH domain-Band 7 family mit_SMPDase PF14724.1 ETO20390.1 - 0.29 8.8 2.0 0.38 8.4 1.4 1.1 1 0 0 1 1 1 0 Mitochondrial-associated sphingomyelin phosphodiesterase CytadhesinP1 PF12378.3 ETO20390.1 - 3.4 7.6 8.6 0.98 9.4 0.3 2.5 2 0 0 2 2 2 0 Trypsin-sensitive surface-exposed protein Clathrin-link PF09268.5 ETO20392.1 - 0.026 13.5 0.1 0.063 12.3 0.1 1.6 1 0 0 1 1 1 0 Clathrin, heavy-chain linker DUF2357 PF09823.4 ETO20394.1 - 0.07 12.2 2.5 0.19 10.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2357) AMP-binding PF00501.23 ETO20395.1 - 1.5e-40 138.9 0.0 1.9e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETO20395.1 - 0.0061 17.4 0.0 0.012 16.5 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 ETO20396.1 - 2e-07 29.7 0.0 3.2e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme VWA_3 PF13768.1 ETO20397.1 - 0.0008 19.1 0.2 0.34 10.5 0.0 2.6 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_CoxE PF05762.9 ETO20397.1 - 0.0023 17.0 0.0 0.81 8.7 0.0 2.4 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein Sigma_reg_N PF13800.1 ETO20399.1 - 0.0019 18.2 0.2 0.0019 18.2 0.1 2.2 2 1 0 2 2 2 1 Sigma factor regulator N-terminal Crystall_2 PF09076.5 ETO20399.1 - 0.029 14.1 2.2 0.029 14.1 1.5 1.8 2 0 0 2 2 2 0 Beta/Gamma crystallin Zip PF02535.17 ETO20399.1 - 0.094 11.7 0.5 6.1 5.7 0.1 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter DUF2899 PF11449.3 ETO20399.1 - 0.41 9.7 2.2 0.31 10.1 0.5 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2899) Methyltransf_12 PF08242.7 ETO20399.1 - 0.8 10.2 3.0 2.4 8.6 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain YajC PF02699.10 ETO20399.1 - 1 9.1 0.0 1 9.1 0.0 2.4 2 1 0 2 2 2 0 Preprotein translocase subunit DUF443 PF04276.7 ETO20399.1 - 1.6 8.0 10.1 1.5 8.2 1.4 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF443) PBP1_TM PF14812.1 ETO20399.1 - 3.3 8.0 7.4 0.19 12.0 0.7 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PUF PF00806.14 ETO20400.1 - 2.2e-19 67.7 3.6 0.00014 21.1 0.0 6.1 6 0 0 6 6 6 4 Pumilio-family RNA binding repeat DUF1387 PF07139.6 ETO20400.1 - 0.025 14.2 8.2 0.044 13.3 5.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Spore_YtfJ PF09579.5 ETO20400.1 - 0.078 12.8 4.5 0.23 11.3 3.1 1.7 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) Baculo_11_kDa PF06143.6 ETO20400.1 - 0.3 10.4 3.1 4 6.8 0.1 2.8 2 0 0 2 2 2 0 Baculovirus 11 kDa family SART-1 PF03343.8 ETO20400.1 - 0.37 9.0 8.2 0.49 8.6 5.7 1.1 1 0 0 1 1 1 0 SART-1 family DUF1754 PF08555.5 ETO20400.1 - 0.6 10.7 12.1 1.4 9.5 8.4 1.6 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) NST1 PF13945.1 ETO20400.1 - 1.7 8.6 9.8 4 7.4 6.8 1.7 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF547 PF04784.9 ETO20400.1 - 2.3 8.1 6.8 4.3 7.2 3.1 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF547 PCNA_N PF00705.13 ETO20401.1 - 6.5e-39 132.3 1.0 1.4e-38 131.2 0.7 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 ETO20401.1 - 5e-35 120.2 1.6 9.2e-19 67.6 0.0 2.9 2 1 1 3 3 3 2 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.11 ETO20401.1 - 2.3e-08 33.1 4.8 2.4e-06 26.5 3.3 2.3 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 ETO20401.1 - 4.3e-07 29.3 2.3 5.7e-07 28.9 0.4 1.8 1 1 0 2 2 2 1 Rad9 PH PF00169.24 ETO20402.1 - 0.00017 21.7 0.4 0.00033 20.8 0.3 1.6 1 0 0 1 1 1 1 PH domain DUF3439 PF11921.3 ETO20402.1 - 0.33 10.7 3.0 0.61 9.8 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) RabGAP-TBC PF00566.13 ETO20403.1 - 2.3e-13 50.1 0.1 2.7e-13 49.8 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF1744 PF08490.7 ETO20403.1 - 0.072 11.6 0.3 0.084 11.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) Glucos_trans_II PF14264.1 ETO20403.1 - 1.1 8.1 10.2 1.4 7.8 5.2 1.8 1 1 0 1 1 1 0 Glucosyl transferase GtrII RXT2_N PF08595.6 ETO20404.1 - 0.0091 15.8 3.5 0.014 15.1 2.4 1.3 1 0 0 1 1 1 1 RXT2-like, N-terminal DUF4611 PF15387.1 ETO20404.1 - 0.077 13.1 5.3 0.13 12.3 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Nop14 PF04147.7 ETO20404.1 - 0.08 10.8 3.1 0.1 10.5 2.1 1.1 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.6 ETO20404.1 - 0.14 9.9 5.5 0.21 9.4 3.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PBP1_TM PF14812.1 ETO20404.1 - 0.54 10.5 10.0 0.99 9.7 6.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 ETO20404.1 - 0.95 8.9 8.6 1.8 8.0 6.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 ETO20404.1 - 2.3 7.8 4.9 3.3 7.2 3.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.7 ETO20404.1 - 4.9 6.3 10.0 7.3 5.7 7.0 1.2 1 0 0 1 1 1 0 NOA36 protein SNARE PF05739.14 ETO20406.1 - 2e-15 56.1 3.6 4.1e-15 55.2 1.1 2.6 2 0 0 2 2 2 1 SNARE domain Ribosomal_L3 PF00297.17 ETO20406.1 - 0.047 13.0 0.2 0.081 12.3 0.1 1.4 1 1 0 1 1 1 0 Ribosomal protein L3 Syntaxin PF00804.20 ETO20406.1 - 2.7 8.1 15.9 0.077 13.1 1.5 3.6 1 1 2 3 3 3 0 Syntaxin BLOC1_2 PF10046.4 ETO20406.1 - 6.3 6.9 9.8 0.77 9.9 0.8 3.2 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-RanBP PF00641.13 ETO20409.1 - 1.7e-07 30.1 3.1 3.5e-07 29.2 2.1 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DZR PF12773.2 ETO20409.1 - 0.0074 16.0 0.3 0.017 14.9 0.2 1.5 1 0 0 1 1 1 1 Double zinc ribbon zf-Sec23_Sec24 PF04810.10 ETO20409.1 - 0.038 13.5 0.6 0.038 13.5 0.4 2.2 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger Tim54 PF11711.3 ETO20409.1 - 0.098 11.2 0.6 0.12 10.9 0.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 WD40 PF00400.27 ETO20411.1 - 1.9e-40 135.3 8.9 1.7e-12 46.7 0.1 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO20411.1 - 0.00019 19.8 0.6 1.9 6.7 0.0 3.0 2 1 1 3 3 3 3 Cytochrome D1 heme domain PD40 PF07676.7 ETO20411.1 - 0.00069 19.2 6.2 1.9 8.2 0.1 4.1 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO20411.1 - 0.0036 15.5 6.8 1.1 7.3 0.2 3.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO20411.1 - 0.057 13.1 0.1 0.63 9.7 0.0 2.2 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 ETO20411.1 - 0.07 11.8 2.6 1.1 7.9 1.8 2.8 1 1 0 1 1 1 0 Nup133 N terminal like Kelch_1 PF01344.20 ETO20412.1 - 5.3e-05 22.6 9.7 0.0078 15.7 0.1 4.4 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 ETO20412.1 - 0.00072 19.6 4.1 0.051 13.7 0.1 4.2 5 0 0 5 5 5 1 Kelch motif Peptidase_M3 PF01432.15 ETO20413.1 - 2.4e-36 125.7 0.7 1.7e-20 73.5 1.8 2.3 2 0 0 2 2 2 2 Peptidase family M3 DUF2458 PF10454.4 ETO20413.1 - 0.037 13.9 1.1 0.095 12.5 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) VWA PF00092.23 ETO20414.1 - 5.6e-05 22.9 0.1 0.00017 21.3 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain WD40 PF00400.27 ETO20418.1 - 2.6e-69 226.8 18.1 2e-13 49.6 0.3 7.0 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO20418.1 - 1.4e-06 26.7 5.5 0.072 11.2 0.3 4.4 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO20418.1 - 0.00012 21.0 6.4 0.31 9.7 0.5 3.9 1 1 4 5 5 5 3 Nup133 N terminal like PD40 PF07676.7 ETO20418.1 - 0.00043 19.8 2.8 2.5 7.8 0.0 4.0 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO20418.1 - 0.0012 18.3 0.1 0.017 14.5 0.1 2.3 1 1 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO20418.1 - 0.0017 16.7 0.3 0.85 7.8 0.0 3.4 1 1 1 4 4 4 1 Cytochrome D1 heme domain DUF1258 PF06869.7 ETO20418.1 - 0.0034 16.4 3.5 0.53 9.3 0.0 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF1258) DUF285 PF03382.9 ETO20418.1 - 0.014 14.9 0.4 0.49 9.9 0.0 3.0 2 1 0 2 2 2 0 Mycoplasma protein of unknown function, DUF285 DPPIV_N PF00930.16 ETO20418.1 - 0.018 13.6 0.1 8.1 4.9 0.0 3.4 1 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region IKI3 PF04762.7 ETO20418.1 - 0.018 12.9 0.0 0.53 8.0 0.0 2.1 2 0 0 2 2 2 0 IKI3 family Resistin PF06954.6 ETO20418.1 - 0.038 14.2 0.3 30 4.9 0.0 4.1 3 1 0 4 4 4 0 Resistin Coatomer_WDAD PF04053.9 ETO20418.1 - 0.053 12.3 1.6 3.5 6.3 0.0 2.3 1 1 2 3 3 3 0 Coatomer WD associated region Proteasome_A_N PF10584.4 ETO20418.1 - 0.24 10.7 1.2 24 4.3 0.0 3.3 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Kelch_6 PF13964.1 ETO20419.1 - 2.6e-10 40.0 6.7 0.00086 19.3 0.1 4.5 4 1 1 5 5 5 3 Kelch motif Kelch_1 PF01344.20 ETO20419.1 - 1.4e-09 37.3 9.7 0.0013 18.2 0.2 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.1 ETO20419.1 - 5.6e-08 32.5 2.6 0.23 11.4 0.1 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 ETO20419.1 - 8.1e-07 28.5 4.3 0.2 11.4 0.1 5.4 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 ETO20419.1 - 3.7e-06 26.9 2.5 0.003 17.6 0.0 4.7 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO20419.1 - 0.0001 22.0 4.9 5.8 6.7 0.1 5.1 4 1 1 5 5 5 2 Galactose oxidase, central domain N_Asn_amidohyd PF14736.1 ETO20419.1 - 0.066 12.0 0.0 9.3 5.0 0.0 2.2 2 0 0 2 2 2 0 Protein N-terminal asparagine amidohydrolase WD40 PF00400.27 ETO20420.1 - 6.3e-73 238.2 11.6 2e-13 49.6 0.2 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO20420.1 - 1.7e-10 39.7 7.0 0.032 12.3 0.0 5.7 1 1 5 6 6 6 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO20420.1 - 2.5e-05 23.2 9.6 0.83 8.3 0.4 4.7 1 1 4 5 5 5 3 Nup133 N terminal like PD40 PF07676.7 ETO20420.1 - 0.00014 21.4 0.4 3 7.5 0.0 3.9 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO20420.1 - 0.00015 20.2 1.6 0.55 8.4 0.1 3.1 1 1 2 3 3 3 3 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO20420.1 - 0.00048 19.3 1.3 5.3 6.0 0.0 3.8 1 1 3 4 4 4 3 Neuroblastoma-amplified sequence, N terminal Gmad1 PF10647.4 ETO20420.1 - 0.002 17.5 0.0 0.049 13.0 0.0 2.2 1 1 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain DPPIV_N PF00930.16 ETO20420.1 - 0.0058 15.2 0.2 0.6 8.6 0.0 3.0 1 1 3 4 4 4 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region PQQ_2 PF13360.1 ETO20420.1 - 0.028 13.8 0.6 0.24 10.8 0.3 2.1 1 1 1 2 2 2 0 PQQ-like domain Proteasome_A_N PF10584.4 ETO20420.1 - 0.23 10.8 4.6 12 5.3 0.1 3.8 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 ETO20421.1 - 4.1e-59 194.4 13.4 2.3e-11 43.1 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO20421.1 - 1.1e-06 28.5 0.0 2.2e-05 24.4 0.0 3.0 2 0 0 2 2 2 1 Kelch motif PQQ_2 PF13360.1 ETO20421.1 - 3.4e-05 23.4 0.1 0.58 9.5 0.0 2.5 2 1 0 2 2 2 1 PQQ-like domain Nup160 PF11715.3 ETO20421.1 - 0.00023 19.4 5.6 0.032 12.3 0.2 3.9 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Kelch_4 PF13418.1 ETO20421.1 - 0.00059 19.5 0.0 0.014 15.1 0.0 3.1 3 0 0 3 3 3 1 Galactose oxidase, central domain B_lectin PF01453.19 ETO20421.1 - 0.0023 17.8 0.7 0.022 14.6 0.2 2.5 2 0 0 2 2 2 1 D-mannose binding lectin Kelch_2 PF07646.10 ETO20421.1 - 0.029 14.1 0.0 0.17 11.6 0.0 2.4 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.1 ETO20421.1 - 0.047 13.8 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO20421.1 - 0.1 12.5 0.1 0.26 11.2 0.1 1.7 1 0 0 1 1 1 0 Kelch motif DUF1652 PF07865.6 ETO20421.1 - 0.13 11.8 0.1 5.6 6.6 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1652) Utp14 PF04615.8 ETO20422.1 - 10 4.1 28.5 13 3.8 19.8 1.1 1 0 0 1 1 1 0 Utp14 protein DUF4254 PF14063.1 ETO20425.1 - 0.0067 16.0 2.9 0.0094 15.5 1.1 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF4254) RGS PF00615.14 ETO20426.1 - 0.0011 19.0 0.3 0.0015 18.6 0.2 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF4638 PF15472.1 ETO20428.1 - 0.4 10.2 9.6 0.44 10.1 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) FAM60A PF15396.1 ETO20428.1 - 0.58 9.8 10.2 0.72 9.5 7.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Plasmodium_Vir PF05795.6 ETO20428.1 - 0.71 9.0 12.9 0.71 9.0 8.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DDRGK PF09756.4 ETO20428.1 - 0.81 9.0 15.5 1.1 8.6 10.7 1.2 1 0 0 1 1 1 0 DDRGK domain DHHW PF14286.1 ETO20428.1 - 2 7.6 10.0 2.3 7.4 6.9 1.1 1 0 0 1 1 1 0 DHHW protein Mem_trans PF03547.13 ETO20428.1 - 4.2 5.5 6.9 4.3 5.5 4.8 1.1 1 0 0 1 1 1 0 Membrane transport protein DNA_pol_viral_N PF00242.12 ETO20428.1 - 8.9 5.2 12.0 9.5 5.1 8.3 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain BTB PF00651.26 ETO20429.1 - 5e-12 45.7 0.5 4.7e-11 42.6 0.1 2.0 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.10 ETO20429.1 - 0.0078 16.0 0.2 0.028 14.2 0.0 2.0 2 1 1 3 3 3 1 BTB And C-terminal Kelch AAA PF00004.24 ETO20430.1 - 5.7e-09 36.2 3.3 0.00049 20.2 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 ETO20430.1 - 0.0011 18.8 0.1 0.0042 16.9 0.0 2.0 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Mg_chelatase PF01078.16 ETO20430.1 - 0.017 14.3 0.0 0.033 13.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 ETO20430.1 - 0.025 14.2 0.0 1.6 8.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF1765 PF08578.5 ETO20431.1 - 8.2e-10 38.8 2.2 8.2e-10 38.8 1.6 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) C8 PF08742.6 ETO20434.1 - 0.12 12.6 9.4 0.78 10.0 3.6 2.4 2 0 0 2 2 2 0 C8 domain Cut12 PF11500.3 ETO20435.1 - 0.014 15.1 2.7 0.022 14.4 1.9 1.3 1 0 0 1 1 1 0 Spindle pole body formation-associated protein DUF3899 PF13038.1 ETO20435.1 - 0.018 15.1 0.1 0.03 14.4 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3899) CENP-B_dimeris PF09026.5 ETO20435.1 - 0.02 15.1 1.3 0.022 15.0 0.1 1.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Myc_N PF01056.13 ETO20435.1 - 0.026 13.7 3.3 0.029 13.5 2.3 1.1 1 0 0 1 1 1 0 Myc amino-terminal region PBP1_TM PF14812.1 ETO20435.1 - 0.037 14.3 0.2 0.037 14.3 0.1 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BSP_II PF05432.6 ETO20435.1 - 0.06 12.6 11.5 0.079 12.2 8.0 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Ctr PF04145.10 ETO20435.1 - 0.061 13.3 0.0 0.076 13.0 0.0 1.2 1 0 0 1 1 1 0 Ctr copper transporter family EBV-NA3 PF05009.7 ETO20435.1 - 0.34 10.1 1.7 0.45 9.7 1.2 1.1 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Ribosomal_60s PF00428.14 ETO20435.1 - 1.8 8.9 5.8 2.7 8.4 4.0 1.4 1 1 0 1 1 1 0 60s Acidic ribosomal protein IncA PF04156.9 ETO20436.1 - 0.0034 16.9 5.1 0.0034 16.9 3.5 3.0 1 1 1 2 2 2 1 IncA protein DivIVA PF05103.8 ETO20436.1 - 0.011 15.8 2.4 0.011 15.8 1.7 3.9 3 1 1 4 4 4 0 DivIVA protein CENP-F_leu_zip PF10473.4 ETO20436.1 - 0.027 14.3 4.3 0.027 14.3 3.0 4.1 2 1 0 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_2 PF07716.10 ETO20436.1 - 0.042 13.6 1.6 0.042 13.6 1.1 5.0 4 1 1 5 5 4 0 Basic region leucine zipper Atg14 PF10186.4 ETO20436.1 - 0.33 9.8 23.8 0.56 9.1 6.9 2.4 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF972 PF06156.8 ETO20436.1 - 0.75 10.1 31.8 0.32 11.3 2.7 3.9 1 1 2 4 4 4 0 Protein of unknown function (DUF972) HALZ PF02183.13 ETO20436.1 - 1.5 8.6 20.6 0.54 10.0 1.0 4.8 4 2 0 4 4 4 0 Homeobox associated leucine zipper Baculo_PEP_C PF04513.7 ETO20436.1 - 1.5 8.6 9.8 0.41 10.4 1.2 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cep57_CLD_2 PF14197.1 ETO20436.1 - 1.8 8.5 34.7 0.14 12.1 1.6 5.2 4 2 0 4 4 4 0 Centrosome localisation domain of PPC89 DivIC PF04977.10 ETO20436.1 - 1.9 7.9 21.0 0.44 10.0 0.1 4.2 4 1 0 4 4 4 0 Septum formation initiator Pox_A_type_inc PF04508.7 ETO20436.1 - 3.4 7.7 10.9 2.2 8.2 1.1 4.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat NPV_P10 PF05531.7 ETO20436.1 - 5.3 7.3 12.8 9 6.6 2.9 4.2 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF2570 PF10828.3 ETO20436.1 - 8.1 6.0 18.2 5.3 6.6 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2570) Xpo1 PF08389.7 ETO20437.1 - 0.0027 17.6 0.0 0.0051 16.7 0.0 1.5 1 0 0 1 1 1 1 Exportin 1-like protein TetR_C_8 PF14278.1 ETO20437.1 - 0.18 12.2 2.8 5.4 7.4 0.1 2.4 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region FANCI_S4 PF14678.1 ETO20438.1 - 0.076 12.1 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 FANCI solenoid 4 PUA PF01472.15 ETO20441.1 - 9.2e-13 47.7 0.0 1.5e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 PUA domain LRR_8 PF13855.1 ETO20442.1 - 7e-12 44.9 20.4 3.4e-08 33.1 5.9 4.4 4 1 2 6 6 6 3 Leucine rich repeat LRR_4 PF12799.2 ETO20442.1 - 4.8e-10 38.8 22.6 1.5e-06 27.6 2.0 4.7 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETO20442.1 - 2.4e-06 26.7 18.7 0.18 11.9 0.2 7.5 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_7 PF13504.1 ETO20442.1 - 0.19 12.0 12.7 24 5.7 0.2 6.1 6 0 0 6 6 6 0 Leucine rich repeat LRR_6 PF13516.1 ETO20442.1 - 0.39 10.9 12.8 3.2 8.1 0.1 5.0 5 0 0 5 5 5 0 Leucine Rich repeat ASFV_J13L PF05568.6 ETO20442.1 - 4.2 6.8 4.6 7.1 6.1 2.0 2.3 1 1 0 1 1 1 0 African swine fever virus J13L protein PBP1_TM PF14812.1 ETO20444.1 - 9.6 6.5 21.7 3 8.2 0.8 3.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pkinase PF00069.20 ETO20445.1 - 2.1e-35 122.1 0.0 2.1e-35 122.1 0.0 1.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO20445.1 - 4.3e-15 55.4 0.0 4.3e-15 55.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase DUF3195 PF11424.3 ETO20445.1 - 0.015 15.4 0.2 0.037 14.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3195) Myc_N PF01056.13 ETO20445.1 - 0.018 14.1 5.8 0.025 13.7 4.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Seadorna_VP7 PF07387.6 ETO20445.1 - 0.041 12.7 0.0 0.073 11.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 TCO89 PF10452.4 ETO20445.1 - 0.051 12.4 4.4 0.063 12.1 3.1 1.1 1 0 0 1 1 1 0 TORC1 subunit TCO89 CDC45 PF02724.9 ETO20445.1 - 0.12 10.4 5.0 0.14 10.1 3.5 1.1 1 0 0 1 1 1 0 CDC45-like protein RNase_H2-Ydr279 PF09468.5 ETO20445.1 - 0.13 11.4 8.1 0.22 10.6 5.6 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) SID-1_RNA_chan PF13965.1 ETO20445.1 - 0.29 9.2 4.3 0.4 8.7 3.0 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Tim54 PF11711.3 ETO20445.1 - 0.44 9.0 5.4 0.63 8.5 3.7 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Ycf1 PF05758.7 ETO20445.1 - 0.65 7.6 5.6 0.75 7.4 3.9 1.1 1 0 0 1 1 1 0 Ycf1 DDHD PF02862.12 ETO20445.1 - 2.8 7.6 5.1 4.1 7.1 3.6 1.3 1 0 0 1 1 1 0 DDHD domain 2-oxoacid_dh PF00198.18 ETO20446.1 - 0.0023 17.2 0.9 0.0038 16.5 0.6 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) DUF4199 PF13858.1 ETO20446.1 - 0.058 13.3 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Glucos_trans_II PF14264.1 ETO20446.1 - 0.069 12.1 0.4 0.095 11.6 0.3 1.1 1 0 0 1 1 1 0 Glucosyl transferase GtrII DUF2626 PF11117.3 ETO20446.1 - 0.087 13.2 0.6 0.18 12.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2626) Rsd_AlgQ PF04353.8 ETO20446.1 - 0.095 12.4 4.1 0.18 11.4 0.8 2.1 2 0 0 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ DUF3464 PF11947.3 ETO20446.1 - 0.52 9.7 0.0 0.52 9.7 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3464) TPP_enzyme_N PF02776.13 ETO20447.1 - 4.8e-16 58.7 0.0 6.9e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DUF1754 PF08555.5 ETO20447.1 - 0.011 16.3 8.5 0.016 15.7 5.9 1.3 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Kelch_5 PF13854.1 ETO20448.1 - 0.00019 21.2 8.7 0.38 10.7 0.1 5.2 5 1 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO20448.1 - 0.0031 17.0 8.5 1.7 8.2 0.3 4.7 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO20448.1 - 0.0063 16.6 9.5 5.7 7.2 0.1 4.9 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO20448.1 - 0.016 14.9 2.8 2 8.3 0.0 4.3 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.1 ETO20448.1 - 0.85 9.4 3.7 5.5 6.8 0.1 3.6 4 0 0 4 4 4 0 Galactose oxidase, central domain Myticin-prepro PF10690.4 ETO20448.1 - 0.9 9.6 4.3 2.3 8.3 0.3 2.4 1 1 1 2 2 2 0 Myticin pre-proprotein from the mussel ADIP PF11559.3 ETO20449.1 - 0.00027 20.8 8.3 0.00043 20.2 2.8 2.7 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding CENP-Q PF13094.1 ETO20449.1 - 0.17 11.9 4.3 0.072 13.1 1.1 1.6 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Cep57_MT_bd PF06657.8 ETO20449.1 - 0.25 11.2 2.8 0.68 9.9 2.0 1.7 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Seryl_tRNA_N PF02403.17 ETO20449.1 - 0.57 10.2 4.3 3.3 7.7 0.7 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain V-set_CD47 PF08204.6 ETO20449.1 - 1.9 8.2 7.2 1.4 8.6 0.1 2.6 1 1 2 3 3 3 0 CD47 immunoglobulin-like domain SAM_1 PF00536.25 ETO20450.1 - 9.7e-15 54.5 0.1 1.7e-14 53.7 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO20450.1 - 3.4e-14 52.4 0.1 6.1e-14 51.6 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 ETO20450.1 - 0.024 14.3 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain DUF1777 PF08648.7 ETO20450.1 - 2.9 7.5 8.2 8.9 6.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) DUF3385 PF11865.3 ETO20451.1 - 0.0067 16.3 0.9 0.017 15.0 0.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3385) Sec20 PF03908.8 ETO20453.1 - 0.1 12.3 1.5 0.22 11.2 1.1 1.6 1 0 0 1 1 1 0 Sec20 Lipase_chap PF03280.9 ETO20455.1 - 0.0039 16.7 1.3 0.0054 16.2 0.9 1.3 1 0 0 1 1 1 1 Proteobacterial lipase chaperone protein AAA_13 PF13166.1 ETO20455.1 - 0.0083 14.6 10.0 0.01 14.3 6.9 1.0 1 0 0 1 1 1 1 AAA domain FliD_N PF02465.13 ETO20455.1 - 0.02 15.2 9.2 1.2 9.5 0.2 2.5 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 N-terminus CTI PF06934.6 ETO20455.1 - 0.033 12.4 3.4 0.039 12.2 2.3 1.0 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) CENP-F_leu_zip PF10473.4 ETO20455.1 - 0.041 13.7 14.7 0.26 11.1 10.5 1.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 K-box PF01486.12 ETO20455.1 - 0.055 13.2 10.5 0.77 9.5 7.2 2.2 1 1 0 1 1 1 0 K-box region Apolipoprotein PF01442.13 ETO20455.1 - 0.057 12.9 3.9 0.085 12.3 2.7 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Prominin PF05478.6 ETO20455.1 - 0.057 10.9 6.6 0.069 10.6 4.6 1.1 1 0 0 1 1 1 0 Prominin Phlebovirus_NSM PF07246.6 ETO20455.1 - 0.075 12.1 7.2 0.1 11.7 5.0 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M TPR_MLP1_2 PF07926.7 ETO20455.1 - 0.078 12.7 11.7 0.68 9.6 7.7 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF241 PF03087.9 ETO20455.1 - 0.083 12.3 7.3 0.069 12.6 4.3 1.4 1 1 0 1 1 1 0 Arabidopsis protein of unknown function DUF2528 PF10800.3 ETO20455.1 - 0.092 13.1 0.4 0.24 11.8 0.1 1.9 1 1 1 2 2 1 0 Protein of unknown function (DUF2528) Mnd1 PF03962.10 ETO20455.1 - 0.097 12.3 11.5 0.14 11.7 3.4 2.1 1 1 1 2 2 2 0 Mnd1 family DUF87 PF01935.12 ETO20455.1 - 0.14 11.9 3.8 0.19 11.5 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF342 PF03961.8 ETO20455.1 - 0.15 10.4 8.1 0.21 9.9 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2203 PF09969.4 ETO20455.1 - 0.15 12.2 1.7 0.26 11.5 1.2 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Alpha-2-MRAP_C PF06401.6 ETO20455.1 - 0.15 11.8 9.6 0.51 10.1 6.6 1.9 1 1 1 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain Syntaxin PF00804.20 ETO20455.1 - 0.2 11.8 11.6 0.14 12.3 6.4 1.8 1 1 1 2 2 2 0 Syntaxin Fib_alpha PF08702.5 ETO20455.1 - 0.23 11.5 10.6 0.41 10.7 7.3 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF148 PF02520.12 ETO20455.1 - 0.23 11.2 9.0 1.5 8.5 4.8 2.2 1 1 1 2 2 2 0 Domain of unknown function DUF148 PspA_IM30 PF04012.7 ETO20455.1 - 0.26 10.5 9.0 0.8 9.0 1.8 2.1 1 1 1 2 2 2 0 PspA/IM30 family Sec5 PF15469.1 ETO20455.1 - 0.32 10.7 9.5 1.1 8.9 6.6 1.9 1 1 0 1 1 1 0 Exocyst complex component Sec5 Med10 PF09748.4 ETO20455.1 - 0.36 10.6 5.8 4.3 7.1 4.0 2.2 1 1 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex Baculo_PEP_C PF04513.7 ETO20455.1 - 0.38 10.5 8.0 0.97 9.2 4.7 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cytochrom_B562 PF07361.6 ETO20455.1 - 0.39 11.1 6.4 0.78 10.1 4.4 1.5 1 0 0 1 1 1 0 Cytochrome b562 V-ATPase_G PF03179.10 ETO20455.1 - 0.46 10.8 9.0 0.54 10.5 4.5 2.0 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit Ribosomal_L50 PF10501.4 ETO20455.1 - 0.47 10.4 5.5 0.34 10.8 2.5 1.8 1 1 0 1 1 1 0 Ribosomal subunit 39S AF0941-like PF14591.1 ETO20455.1 - 0.49 10.4 8.6 1.4 8.9 5.9 1.7 1 1 0 1 1 1 0 AF0941-like DUF3552 PF12072.3 ETO20455.1 - 0.55 9.4 11.1 0.89 8.7 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF2228 PF10228.4 ETO20455.1 - 0.71 9.3 7.5 0.7 9.3 3.5 2.1 1 1 2 3 3 3 0 Uncharacterised conserved protein (DUF2228) V_ATPase_I PF01496.14 ETO20455.1 - 0.78 7.5 5.1 1 7.1 3.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.1 ETO20455.1 - 0.83 8.5 3.8 1 8.2 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.7 ETO20455.1 - 1.1 9.5 12.7 4.4 7.6 5.0 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein MerR-DNA-bind PF09278.6 ETO20455.1 - 1.4 9.3 7.2 0.95 9.9 0.7 2.8 2 1 1 3 3 2 0 MerR, DNA binding GLE1 PF07817.8 ETO20455.1 - 1.6 7.6 8.4 2.5 6.9 2.9 2.0 1 1 1 2 2 2 0 GLE1-like protein EAP30 PF04157.11 ETO20455.1 - 1.6 7.8 7.8 2.4 7.2 1.9 2.2 1 1 1 2 2 2 0 EAP30/Vps36 family DUF3450 PF11932.3 ETO20455.1 - 1.9 7.6 9.2 0.67 9.1 3.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DivIC PF04977.10 ETO20455.1 - 2.3 7.7 12.2 2.2 7.8 0.3 2.7 1 1 2 3 3 3 0 Septum formation initiator DUF972 PF06156.8 ETO20455.1 - 2.3 8.5 10.1 2 8.8 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Tmemb_cc2 PF10267.4 ETO20455.1 - 2.4 6.6 12.9 0.72 8.3 0.4 2.0 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein TMPIT PF07851.8 ETO20455.1 - 3 6.8 9.9 1.4 7.9 2.2 1.9 1 1 1 2 2 2 0 TMPIT-like protein Vps51 PF08700.6 ETO20455.1 - 3.7 7.4 8.9 3 7.7 2.9 2.3 1 1 1 2 2 2 0 Vps51/Vps67 IncA PF04156.9 ETO20455.1 - 7 6.1 14.4 4.8 6.7 0.8 2.1 1 1 1 2 2 2 0 IncA protein UPF0449 PF15136.1 ETO20455.1 - 9 6.5 8.2 4.4 7.5 1.9 2.2 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 Cu-oxidase_3 PF07732.10 ETO20456.1 - 4.3e-07 29.6 0.2 7.9e-07 28.8 0.1 1.5 1 0 0 1 1 1 1 Multicopper oxidase DUF3070 PF11270.3 ETO20456.1 - 0.36 10.6 1.6 1.1 9.0 1.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3070) WD40 PF00400.27 ETO20457.1 - 0.00045 19.9 0.1 0.059 13.2 0.1 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat Extensin-like_C PF06904.7 ETO20460.1 - 0.14 11.9 0.6 0.19 11.5 0.2 1.4 1 1 0 1 1 1 0 Extensin-like protein C-terminus ICMT PF04140.9 ETO20461.1 - 1.7e-28 98.6 1.6 4.3e-28 97.3 1.1 1.7 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 ETO20461.1 - 4.2e-11 42.8 2.1 4.2e-11 42.8 1.4 2.5 2 1 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 ETO20461.1 - 0.0075 15.5 0.7 0.013 14.8 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PIRT PF15099.1 ETO20461.1 - 0.051 12.7 0.3 25 4.1 0.0 3.6 3 1 0 4 4 4 0 Phosphoinositide-interacting protein family Pkinase PF00069.20 ETO20462.1 - 2.2e-19 69.6 0.1 9.8e-19 67.5 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO20462.1 - 2.4e-05 23.5 0.0 0.001 18.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase PH_8 PF15409.1 ETO20462.1 - 0.12 12.5 3.2 0.22 11.6 2.2 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Pkinase PF00069.20 ETO20463.1 - 2.4e-06 26.8 0.0 3.1e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.24 ETO20464.1 - 1.6e-19 69.4 0.0 2.9e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain zf-TRAF PF02176.13 ETO20465.1 - 5e-07 30.0 9.4 7e-06 26.3 2.9 3.2 2 0 0 2 2 2 2 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 ETO20465.1 - 0.32 11.0 12.6 0.085 12.9 0.7 4.0 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Trypan_PARP PF05887.6 ETO20466.1 - 0.041 13.6 2.6 0.055 13.2 1.8 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NOA36 PF06524.7 ETO20466.1 - 1.4 8.0 4.6 1.6 7.9 3.2 1.0 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 ETO20467.1 - 0.014 13.3 0.9 0.016 13.1 0.6 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 ETO20467.1 - 0.017 13.2 0.8 0.019 13.0 0.5 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF912 PF06024.7 ETO20467.1 - 1.6 8.8 8.3 0.45 10.5 0.2 2.2 1 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) LMBR1 PF04791.11 ETO20468.1 - 0.079 11.5 3.3 0.091 11.3 2.3 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein CDC27 PF09507.5 ETO20468.1 - 0.48 9.6 39.9 0.59 9.3 27.7 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PLRV_ORF5 PF01690.12 ETO20468.1 - 3.2 6.7 30.5 4 6.4 21.2 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Herpes_LMP2 PF07415.6 ETO20468.1 - 4.7 5.6 9.9 0.26 9.8 3.1 1.5 1 1 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Macoilin PF09726.4 ETO20468.1 - 8.3 4.5 43.1 10 4.2 29.9 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF1777 PF08648.7 ETO20469.1 - 0.0065 16.2 54.4 0.013 15.2 37.8 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1777) DUF1510 PF07423.6 ETO20469.1 - 0.09 12.1 17.3 0.12 11.7 12.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Daxx PF03344.10 ETO20469.1 - 0.14 10.6 17.8 0.15 10.5 12.4 1.0 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 ETO20469.1 - 0.31 8.8 24.7 0.36 8.6 17.1 1.0 1 0 0 1 1 1 0 Nop14-like family MIP-T3 PF10243.4 ETO20469.1 - 0.42 9.0 31.6 0.47 8.8 21.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Corona_nucleoca PF00937.13 ETO20469.1 - 4.8 6.0 16.8 6 5.7 11.6 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein SAPS PF04499.10 ETO20469.1 - 4.8 5.7 13.7 5.5 5.4 9.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Gag_spuma PF03276.9 ETO20469.1 - 5.4 5.2 8.1 6.1 5.0 5.6 1.2 1 0 0 1 1 1 0 Spumavirus gag protein CAP_C PF08603.6 ETO20470.1 - 7.8e-10 38.3 5.3 1.4e-09 37.5 3.7 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 ETO20470.1 - 7.9e-07 28.5 12.8 3.1e-06 26.5 8.9 1.9 1 1 1 2 2 2 2 Tubulin binding cofactor C YEATS PF03366.11 ETO20470.1 - 0.0002 21.0 0.1 0.0013 18.4 0.1 2.4 2 1 0 2 2 2 1 YEATS family Kelch_5 PF13854.1 ETO20471.1 - 0.27 11.2 2.3 13 5.8 0.1 3.3 3 0 0 3 3 3 0 Kelch motif IQ PF00612.22 ETO20472.1 - 0.00028 20.2 5.1 0.0035 16.8 0.0 4.1 4 0 0 4 4 4 1 IQ calmodulin-binding motif DUF106 PF01956.11 ETO20472.1 - 0.061 12.8 5.3 0.043 13.3 1.6 2.0 2 0 0 2 2 2 0 Integral membrane protein DUF106 G-alpha PF00503.15 ETO20473.1 - 5.1e-11 41.8 11.5 7.3e-11 41.3 7.6 1.3 1 1 0 1 1 1 1 G-protein alpha subunit AAA_29 PF13555.1 ETO20473.1 - 0.0042 16.5 0.8 0.02 14.4 0.0 2.4 3 0 0 3 3 3 1 P-loop containing region of AAA domain DUF4302 PF14135.1 ETO20473.1 - 0.012 14.9 0.6 0.024 13.9 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4302) MMR_HSR1 PF01926.18 ETO20473.1 - 0.016 15.1 0.5 0.029 14.3 0.0 1.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase Phytoreo_S7 PF07236.6 ETO20473.1 - 0.036 12.3 3.0 0.041 12.1 2.1 1.1 1 0 0 1 1 1 0 Phytoreovirus S7 protein Tox-PLDMTX PF15645.1 ETO20473.1 - 0.12 12.4 2.9 0.22 11.5 0.7 2.0 2 0 0 2 2 2 0 Dermonecrotoxin of the Papain-like fold Arf PF00025.16 ETO20473.1 - 0.24 10.5 0.1 0.24 10.5 0.1 2.3 3 1 0 3 3 3 0 ADP-ribosylation factor family Miro PF08477.8 ETO20473.1 - 0.5 10.8 0.0 0.5 10.8 0.0 2.6 2 1 0 3 3 3 0 Miro-like protein YqzH PF14164.1 ETO20474.1 - 0.021 14.7 0.9 0.093 12.6 0.6 2.2 1 0 0 1 1 1 0 YqzH-like protein IL2 PF00715.12 ETO20474.1 - 0.03 14.0 0.0 0.1 12.3 0.0 1.9 1 0 0 1 1 1 0 Interleukin 2 B56 PF01603.15 ETO20475.1 - 2.6e-54 184.3 2.4 3.3e-54 184.0 1.7 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Arm PF00514.18 ETO20475.1 - 0.11 12.3 0.0 0.46 10.3 0.0 2.1 1 1 1 2 2 2 0 Armadillo/beta-catenin-like repeat MIP-T3 PF10243.4 ETO20476.1 - 0.0001 20.9 33.6 0.00012 20.7 23.3 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 ABC2_membrane_3 PF12698.2 ETO20476.1 - 0.028 13.4 7.0 0.045 12.7 4.8 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Nop14 PF04147.7 ETO20476.1 - 0.16 9.8 37.3 0.25 9.2 25.8 1.3 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 ETO20476.1 - 0.18 10.8 38.4 0.32 10.0 26.6 1.4 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 ETO20476.1 - 0.35 9.2 42.8 0.49 8.8 29.6 1.2 1 0 0 1 1 1 0 Daxx Family TFIIF_alpha PF05793.7 ETO20476.1 - 5.9 5.1 44.1 7.8 4.7 30.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) WD40 PF00400.27 ETO20477.1 - 4.6e-13 48.4 1.0 7.7e-08 31.9 0.0 4.0 3 1 0 3 3 3 2 WD domain, G-beta repeat CDC45 PF02724.9 ETO20477.1 - 0.22 9.4 13.4 0.3 9.0 9.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Mem_trans PF03547.13 ETO20477.1 - 0.41 8.8 4.0 0.53 8.5 2.8 1.2 1 0 0 1 1 1 0 Membrane transport protein DUF2457 PF10446.4 ETO20477.1 - 1.1 7.9 18.3 1.6 7.3 12.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Menin PF05053.8 ETO20477.1 - 4.3 5.3 15.1 7.6 4.5 10.5 1.3 1 0 0 1 1 1 0 Menin Zip PF02535.17 ETO20477.1 - 4.7 6.1 5.1 7.7 5.4 3.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Utp14 PF04615.8 ETO20477.1 - 6.2 4.8 28.0 9.1 4.3 19.4 1.1 1 0 0 1 1 1 0 Utp14 protein DEAD PF00270.24 ETO20481.1 - 2.7e-22 79.0 0.0 2.1e-21 76.1 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETO20481.1 - 8.4e-07 28.7 0.4 4.7e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Zip PF02535.17 ETO20481.1 - 1.7 7.5 10.2 3 6.7 7.1 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.11 ETO20482.1 - 5 6.9 8.1 8.5 6.1 5.6 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1980 PF09323.5 ETO20482.1 - 5.8 6.6 8.8 0.52 10.0 2.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Yippee-Mis18 PF03226.9 ETO20484.1 - 3.2e-07 30.2 0.9 3.2e-07 30.2 0.6 2.1 1 1 1 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Reo_sigmaC PF04582.7 ETO20484.1 - 0.00074 18.7 0.7 0.0011 18.2 0.5 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Prominin PF05478.6 ETO20484.1 - 0.003 15.1 7.2 0.0037 14.8 5.0 1.1 1 0 0 1 1 1 1 Prominin bZIP_1 PF00170.16 ETO20484.1 - 0.0033 17.3 23.1 0.0051 16.7 4.4 3.1 1 1 0 2 2 2 1 bZIP transcription factor V_ATPase_I PF01496.14 ETO20484.1 - 0.0056 14.6 8.8 0.0068 14.3 6.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family APG6 PF04111.7 ETO20484.1 - 0.007 15.4 19.4 0.0097 14.9 13.4 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 Filament PF00038.16 ETO20484.1 - 0.0096 15.4 15.1 0.012 15.0 10.5 1.1 1 0 0 1 1 1 1 Intermediate filament protein IncA PF04156.9 ETO20484.1 - 0.023 14.3 22.2 0.037 13.6 9.9 2.1 1 1 1 2 2 2 0 IncA protein DUF812 PF05667.6 ETO20484.1 - 0.037 12.5 14.8 0.054 12.0 10.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Sec5 PF15469.1 ETO20484.1 - 0.043 13.5 7.1 0.059 13.0 4.9 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec5 Exonuc_VII_L PF02601.10 ETO20484.1 - 0.054 12.6 6.5 0.057 12.6 4.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Flagellin_N PF00669.15 ETO20484.1 - 0.055 13.2 5.3 0.077 12.7 2.8 1.8 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region DUF1395 PF07160.7 ETO20484.1 - 0.063 12.7 12.8 0.089 12.2 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) ERM PF00769.14 ETO20484.1 - 0.063 12.8 22.9 0.11 12.0 15.9 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF3584 PF12128.3 ETO20484.1 - 0.096 10.0 15.7 0.11 9.7 10.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_27 PF13514.1 ETO20484.1 - 0.15 9.7 12.1 0.2 9.3 8.4 1.1 1 0 0 1 1 1 0 AAA domain DUF2400 PF09674.5 ETO20484.1 - 0.15 11.7 5.1 0.23 11.1 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) PEARLI-4 PF05278.7 ETO20484.1 - 0.16 11.3 15.5 0.099 12.0 9.5 1.5 1 1 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Syntaxin_2 PF14523.1 ETO20484.1 - 0.18 11.8 14.2 4.6 7.3 3.0 2.4 1 1 1 2 2 2 0 Syntaxin-like protein LXG PF04740.7 ETO20484.1 - 0.19 11.5 10.8 1.4 8.6 8.0 1.9 1 1 0 1 1 1 0 LXG domain of WXG superfamily zf-C4H2 PF10146.4 ETO20484.1 - 0.2 11.6 17.6 0.27 11.2 12.2 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein Cluap1 PF10234.4 ETO20484.1 - 0.24 10.5 15.2 0.34 10.0 10.5 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF4407 PF14362.1 ETO20484.1 - 0.34 9.8 8.4 0.6 9.0 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF972 PF06156.8 ETO20484.1 - 0.47 10.8 20.0 28 5.1 13.8 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF1664 PF07889.7 ETO20484.1 - 0.59 9.9 10.3 0.27 11.0 3.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) AAA_11 PF13086.1 ETO20484.1 - 0.64 9.5 6.1 0.93 9.0 4.2 1.3 1 0 0 1 1 1 0 AAA domain PilJ PF13675.1 ETO20484.1 - 0.76 10.1 3.8 5.3 7.4 2.6 2.0 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF2205 PF10224.4 ETO20484.1 - 0.82 9.2 15.5 1.3 8.6 1.6 3.2 1 1 2 3 3 3 0 Predicted coiled-coil protein (DUF2205) GAS PF13851.1 ETO20484.1 - 0.84 8.7 24.3 0.13 11.4 12.6 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3571 PF12095.3 ETO20484.1 - 0.89 9.8 8.9 0.4 10.9 1.6 3.1 2 1 2 4 4 3 0 Protein of unknown function (DUF3571) Spc7 PF08317.6 ETO20484.1 - 1.1 7.8 19.9 0.14 10.7 6.0 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein CorA PF01544.13 ETO20484.1 - 1.4 7.8 7.3 6.4 5.7 5.1 1.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2730 PF10805.3 ETO20484.1 - 2 8.1 11.3 4.3 7.1 7.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) Nup54 PF13874.1 ETO20484.1 - 2.1 7.9 16.8 14 5.2 11.6 2.1 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 DivIC PF04977.10 ETO20484.1 - 2.1 7.8 21.7 13 5.3 4.3 3.3 1 1 2 3 3 3 0 Septum formation initiator CCDC155 PF14662.1 ETO20484.1 - 2.2 7.8 24.9 4.8 6.7 17.3 1.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 Mnd1 PF03962.10 ETO20484.1 - 2.3 7.8 22.4 2.2 7.9 12.1 2.0 1 1 0 1 1 1 0 Mnd1 family CtIP_N PF10482.4 ETO20484.1 - 2.3 8.0 20.9 0.2 11.4 7.8 3.2 1 1 3 4 4 4 0 Tumour-suppressor protein CtIP N-terminal domain Sas10_Utp3 PF04000.10 ETO20484.1 - 2.6 8.3 16.3 15 5.8 2.0 3.7 2 1 1 3 3 3 0 Sas10/Utp3/C1D family DUF342 PF03961.8 ETO20484.1 - 3 6.1 18.6 5.7 5.2 12.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) TMPIT PF07851.8 ETO20484.1 - 3.2 6.7 16.2 5.6 5.9 11.2 1.5 1 1 0 1 1 1 0 TMPIT-like protein Med4 PF10018.4 ETO20484.1 - 3.5 6.9 20.9 0.37 10.1 6.8 2.2 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 TMF_TATA_bd PF12325.3 ETO20484.1 - 3.7 7.3 20.8 6.2 6.5 10.1 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Kinesin-relat_1 PF12711.2 ETO20484.1 - 4.4 7.7 20.3 31 5.0 9.4 3.2 1 1 1 2 2 2 0 Kinesin motor Prefoldin_2 PF01920.15 ETO20484.1 - 4.5 7.0 25.2 0.76 9.5 5.0 3.3 1 1 2 3 3 3 0 Prefoldin subunit DUF3391 PF11871.3 ETO20484.1 - 4.9 7.3 10.0 0.41 10.8 2.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) ADIP PF11559.3 ETO20484.1 - 5.1 6.9 22.5 2.9 7.7 9.2 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2481 PF10654.4 ETO20484.1 - 5.2 6.7 15.7 4.3 7.0 3.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2481) TMF_DNA_bd PF12329.3 ETO20484.1 - 5.5 6.8 29.4 3.2 7.6 9.6 3.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Seryl_tRNA_N PF02403.17 ETO20484.1 - 6 6.9 22.4 6.8 6.7 8.7 2.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF948 PF06103.6 ETO20484.1 - 6.3 6.7 7.8 22 5.0 4.5 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2968 PF11180.3 ETO20484.1 - 6.7 6.0 15.5 6.1 6.1 9.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2968) bZIP_Maf PF03131.12 ETO20484.1 - 7.7 6.8 17.0 1.1 9.6 5.5 2.6 1 1 1 2 2 2 0 bZIP Maf transcription factor DUF2680 PF10925.3 ETO20484.1 - 8.9 6.2 8.7 2.1 8.2 0.5 3.1 3 1 0 3 3 2 0 Protein of unknown function (DUF2680) Snf7 PF03357.16 ETO20485.1 - 4e-14 52.3 20.3 4e-14 52.3 14.1 1.5 1 1 1 2 2 2 1 Snf7 DUF1108 PF06531.6 ETO20485.1 - 0.0036 17.4 1.5 0.0036 17.4 1.1 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1108) MOR2-PAG1_C PF14225.1 ETO20485.1 - 0.047 13.4 0.9 0.057 13.1 0.7 1.2 1 0 0 1 1 1 0 Cell morphogenesis C-terminal DUF615 PF04751.9 ETO20485.1 - 0.06 12.9 11.2 0.08 12.5 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF615) Flavi_DEAD PF07652.9 ETO20485.1 - 0.081 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Flavivirus DEAD domain DASH_Dad3 PF08656.5 ETO20485.1 - 0.2 11.3 2.2 0.46 10.2 0.1 2.3 1 1 1 2 2 2 0 DASH complex subunit Dad3 TBPIP PF07106.8 ETO20485.1 - 0.37 10.3 11.1 0.075 12.5 5.3 1.6 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FliL PF03748.9 ETO20485.1 - 2.1 8.4 6.4 0.79 9.7 2.3 1.9 1 1 1 2 2 2 0 Flagellar basal body-associated protein FliL D5_N PF08706.6 ETO20485.1 - 3.4 7.7 6.0 3.4 7.7 3.3 1.7 1 1 0 1 1 1 0 D5 N terminal like RNA_polI_A14 PF08203.6 ETO20485.1 - 4.5 7.5 5.5 57 4.0 0.1 3.0 2 1 1 3 3 3 0 Yeast RNA polymerase I subunit RPA14 PKD_channel PF08016.7 ETO20486.1 - 4.7e-10 38.4 12.7 4.7e-10 38.4 8.8 1.7 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.26 ETO20486.1 - 0.00011 21.5 19.3 0.00011 21.5 13.4 2.1 1 1 0 2 2 2 1 Ion transport protein UPF0182 PF03699.8 ETO20486.1 - 0.91 7.3 10.7 1.2 6.9 7.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DXP_synthase_N PF13292.1 ETO20487.1 - 0.042 12.7 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase MIT PF04212.13 ETO20488.1 - 7.3e-07 28.9 0.3 2e-06 27.5 0.2 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DUF4530 PF15039.1 ETO20488.1 - 0.0009 19.1 8.4 0.0009 19.1 5.8 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4530) Exo_endo_phos PF03372.18 ETO20489.1 - 4.8e-08 33.2 0.0 7e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3048 PF11258.3 ETO20489.1 - 0.093 11.8 0.6 0.12 11.4 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3048) PI3K_p85B PF02192.11 ETO20490.1 - 0.079 12.3 0.1 0.18 11.2 0.1 1.5 1 0 0 1 1 1 0 PI3-kinase family, p85-binding domain zf-H2C2_2 PF13465.1 ETO20491.1 - 1.3e-10 41.0 20.3 1.3e-07 31.5 0.2 4.1 3 0 0 3 3 3 3 Zinc-finger double domain LMBR1 PF04791.11 ETO20491.1 - 0.0056 15.3 0.1 0.0094 14.5 0.1 1.5 1 1 0 1 1 1 1 LMBR1-like membrane protein zf-C2H2_4 PF13894.1 ETO20491.1 - 0.031 14.6 3.0 0.031 14.6 2.1 4.7 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2 PF00096.21 ETO20491.1 - 0.1 12.9 29.2 0.065 13.5 1.5 5.4 5 1 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 ETO20491.1 - 3.5 7.8 19.5 15 5.8 0.5 4.5 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Uricase PF01014.13 ETO20492.1 - 0.0089 16.1 0.4 0.011 15.8 0.3 1.1 1 0 0 1 1 1 1 Uricase Cobl PF09469.5 ETO20492.1 - 0.26 11.2 1.8 0.39 10.7 0.6 1.7 2 0 0 2 2 2 0 Cordon-bleu ubiquitin-like domain DUF4598 PF15370.1 ETO20494.1 - 0.063 13.5 0.1 0.063 13.5 0.1 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4598) DUF1352 PF07086.7 ETO20495.1 - 0.094 12.3 6.1 0.18 11.3 4.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1352) RTC PF01137.16 ETO20495.1 - 0.1 11.3 0.1 2 7.1 0.0 2.3 2 0 0 2 2 2 0 RNA 3'-terminal phosphate cyclase Ribosomal_L20 PF00453.13 ETO20496.1 - 3.7e-11 42.9 1.8 8e-11 41.8 1.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L20 Lung_7-TM_R PF06814.8 ETO20497.1 - 7.8e-28 97.2 12.2 9.9e-28 96.9 8.4 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF3789 PF12664.2 ETO20497.1 - 0.042 13.1 0.1 0.095 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) Beach PF02138.13 ETO20498.1 - 3.9e-66 223.2 0.0 5.9e-66 222.6 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 ETO20498.1 - 2e-13 50.1 1.5 4e-13 49.1 1.0 1.4 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH MIP-T3 PF10243.4 ETO20499.1 - 0.017 13.6 23.7 0.019 13.4 16.4 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SOBP PF15279.1 ETO20499.1 - 0.74 10.1 6.1 0.78 10.0 4.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Kelch_3 PF13415.1 ETO20500.1 - 7.5e-09 35.5 0.8 1.7e-05 24.8 0.0 3.8 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO20500.1 - 2.7e-08 33.2 6.4 0.00048 19.6 0.3 3.6 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.1 ETO20500.1 - 5.8e-08 32.5 4.8 0.0005 20.1 0.1 4.6 4 1 1 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO20500.1 - 1.4e-06 27.9 0.4 0.62 9.8 0.0 4.6 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO20500.1 - 0.0017 18.2 0.4 3.6 7.6 0.1 3.9 4 0 0 4 4 4 1 Kelch motif NFRKB_winged PF14465.1 ETO20500.1 - 0.33 10.7 2.9 1.2 9.0 0.7 2.6 1 1 1 2 2 2 0 NFRKB Winged Helix-like WD40 PF00400.27 ETO20501.1 - 2.8e-80 261.5 16.6 3.7e-13 48.7 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO20501.1 - 2.2e-15 56.8 0.0 3.6e-05 23.5 0.0 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO20501.1 - 2.8e-08 32.3 1.6 0.032 12.3 0.0 4.7 1 1 4 5 5 5 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO20501.1 - 4.5e-07 28.5 0.5 0.00059 18.2 0.1 3.3 1 1 1 3 3 3 3 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO20501.1 - 2.2e-05 23.7 1.9 1.2 8.2 0.0 4.7 1 1 5 6 6 6 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 ETO20501.1 - 7.6e-05 22.2 12.7 8.4 6.1 0.0 6.8 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO20501.1 - 0.00028 19.7 10.9 0.86 8.2 3.7 4.9 1 1 3 4 4 4 3 Nup133 N terminal like DUF1652 PF07865.6 ETO20501.1 - 0.00094 18.7 0.0 1.3 8.7 0.0 3.7 4 0 0 4 4 4 1 Protein of unknown function (DUF1652) DUF3312 PF11768.3 ETO20501.1 - 0.0035 15.6 0.1 0.22 9.6 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3312) DPPIV_N PF00930.16 ETO20501.1 - 0.029 12.9 0.1 3.1 6.2 0.0 3.9 2 1 2 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF1258 PF06869.7 ETO20501.1 - 0.032 13.3 0.2 3.4 6.6 0.0 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF1258) KH_3 PF13014.1 ETO20501.1 - 0.23 11.1 3.4 4 7.1 0.0 4.0 4 0 0 4 4 4 0 KH domain KH_1 PF00013.24 ETO20501.1 - 0.24 11.0 4.7 0.28 10.8 0.0 3.3 4 0 0 4 4 4 0 KH domain FlaG PF03646.10 ETO20501.1 - 0.28 11.3 1.5 1 9.5 0.1 2.2 1 1 0 2 2 2 0 FlaG protein Epimerase PF01370.16 ETO20502.1 - 2e-24 86.3 0.0 2.6e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETO20502.1 - 8.9e-09 34.4 0.0 1.4e-08 33.8 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 ETO20502.1 - 8.9e-08 31.3 0.0 1.4e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 ETO20502.1 - 1.4e-07 31.6 0.1 2.7e-07 30.6 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETO20502.1 - 1.9e-06 27.6 0.1 4e-06 26.6 0.0 1.5 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.7 ETO20502.1 - 3.2e-06 26.2 0.0 0.0068 15.3 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 ETO20502.1 - 5.7e-06 25.4 0.2 8e-06 24.9 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 ETO20502.1 - 0.00042 20.3 0.0 0.00068 19.6 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 ETO20502.1 - 0.00059 18.9 0.1 0.00077 18.5 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NmrA PF05368.8 ETO20502.1 - 0.01 15.0 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family ThiF PF00899.16 ETO20502.1 - 0.026 14.3 2.5 0.13 12.0 0.4 2.1 1 1 1 2 2 2 0 ThiF family UDPG_MGDP_dh_N PF03721.9 ETO20502.1 - 0.035 13.4 0.1 0.057 12.7 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_31 PF13847.1 ETO20502.1 - 0.042 13.4 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.13 ETO20502.1 - 0.095 12.3 0.0 0.18 11.4 0.0 1.4 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 ETO20502.1 - 0.11 12.5 0.1 0.27 11.3 0.1 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 ETO20502.1 - 0.11 12.4 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Epimerase_Csub PF13950.1 ETO20503.1 - 1.7e-12 47.1 0.1 1.1e-10 41.2 0.0 2.2 2 0 0 2 2 2 2 UDP-glucose 4-epimerase C-term subunit Epimerase PF01370.16 ETO20503.1 - 5.9e-06 25.8 0.0 8.8e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Skp1_POZ PF03931.10 ETO20504.1 - 0.012 15.6 0.7 5.6 7.1 0.0 2.5 1 1 1 2 2 2 0 Skp1 family, tetramerisation domain MIT PF04212.13 ETO20505.1 - 0.0031 17.3 1.4 0.011 15.6 1.0 1.9 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DUF572 PF04502.8 ETO20505.1 - 0.038 13.2 12.9 0.053 12.7 8.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) RXT2_N PF08595.6 ETO20505.1 - 1.2 8.9 17.9 0.073 12.8 5.5 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF4611 PF15387.1 ETO20505.1 - 3.2 7.9 11.1 2.3 8.4 3.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 ETO20505.1 - 3.3 7.1 13.1 0.2 11.1 4.0 2.1 2 0 0 2 2 2 0 Nucleoplasmin Sin_N PF04801.8 ETO20506.1 - 0.012 14.5 6.3 0.014 14.3 4.4 1.0 1 0 0 1 1 1 0 Sin-like protein conserved region DUF908 PF06012.7 ETO20506.1 - 0.019 14.3 0.7 0.022 14.0 0.5 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Cellulose_synt PF03552.9 ETO20506.1 - 0.047 11.9 1.0 0.058 11.6 0.7 1.0 1 0 0 1 1 1 0 Cellulose synthase Sec62 PF03839.11 ETO20506.1 - 0.052 12.9 2.1 0.058 12.7 1.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 PXA PF02194.10 ETO20506.1 - 0.12 11.9 0.5 0.16 11.5 0.3 1.2 1 0 0 1 1 1 0 PXA domain DUF2547 PF10818.3 ETO20506.1 - 0.13 12.9 0.7 0.16 12.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2547) Tom37_C PF11801.3 ETO20506.1 - 0.3 10.9 3.5 0.33 10.7 2.4 1.1 1 0 0 1 1 1 0 Tom37 C-terminal domain RRN3 PF05327.6 ETO20506.1 - 0.41 8.6 3.3 0.49 8.4 2.3 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CMS1 PF14617.1 ETO20506.1 - 5.1 6.0 8.2 6.1 5.8 5.7 1.1 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit MRP-S26 PF14943.1 ETO20506.1 - 8.5 5.8 17.3 12 5.4 12.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 TetR_C_8 PF14278.1 ETO20507.1 - 0.45 10.9 3.2 24 5.3 0.2 3.3 3 1 0 3 3 3 0 Transcriptional regulator C-terminal region CDC45 PF02724.9 ETO20507.1 - 0.72 7.8 32.1 0.057 11.4 0.2 2.4 3 0 0 3 3 3 0 CDC45-like protein AIF_C PF14721.1 ETO20507.1 - 0.73 10.0 0.0 0.73 10.0 0.0 3.9 3 1 0 3 3 3 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Nop14 PF04147.7 ETO20507.1 - 3.9 5.2 39.1 0.19 9.6 17.4 2.7 3 0 0 3 3 3 0 Nop14-like family Daxx PF03344.10 ETO20507.1 - 4.6 5.6 50.7 0.12 10.8 19.4 3.1 3 0 0 3 3 3 0 Daxx Family Kelch_6 PF13964.1 ETO20508.1 - 0.00046 20.2 0.0 0.0016 18.4 0.0 2.0 1 0 0 1 1 1 1 Kelch motif Nuc_sug_transp PF04142.10 ETO20509.1 - 4.8e-28 97.8 4.8 5.6e-28 97.6 3.4 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 ETO20509.1 - 4.2e-09 35.7 6.1 1.7e-08 33.7 4.2 1.8 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 ETO20509.1 - 0.0041 17.1 1.5 0.0041 17.1 1.1 2.6 2 1 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 ETO20509.1 - 0.013 15.6 0.4 0.013 15.6 0.3 2.3 2 0 0 2 2 2 0 Multidrug resistance efflux transporter MFS_1 PF07690.11 ETO20509.1 - 0.21 10.2 12.5 0.68 8.5 8.6 1.9 1 1 0 1 1 1 0 Major Facilitator Superfamily DUF4131 PF13567.1 ETO20509.1 - 0.79 9.1 11.9 0.71 9.2 0.8 3.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4131) Bax1-I PF01027.15 ETO20509.1 - 2.1 7.8 13.8 27 4.2 9.6 2.2 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Wzy_C PF04932.10 ETO20509.1 - 6.8 6.4 8.6 2.2 8.0 0.5 2.4 1 1 1 2 2 2 0 O-Antigen ligase TPT PF03151.11 ETO20509.1 - 8.5 6.0 14.4 4 7.0 0.4 3.2 2 1 1 3 3 3 0 Triose-phosphate Transporter family UCH PF00443.24 ETO20510.1 - 3e-46 157.7 6.2 3e-46 157.7 4.3 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO20510.1 - 1.1e-16 61.0 22.3 3.5e-16 59.5 12.0 3.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-H2C2_2 PF13465.1 ETO20513.1 - 9.7e-10 38.2 28.7 0.0039 17.3 0.2 5.1 5 1 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 ETO20513.1 - 0.00014 21.9 0.5 0.00014 21.9 0.4 6.0 5 2 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETO20513.1 - 0.00015 21.8 36.9 0.00016 21.7 0.4 5.5 5 1 0 5 5 5 2 C2H2-type zinc finger zf-Di19 PF05605.7 ETO20513.1 - 0.001 19.1 22.6 0.053 13.6 4.0 3.7 3 1 1 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 ETO20513.1 - 0.0029 17.7 21.4 0.2 11.8 0.2 5.3 5 0 0 5 5 5 2 Zinc-finger of C2H2 type RRN7 PF11781.3 ETO20513.1 - 0.013 14.9 0.2 0.013 14.9 0.1 3.7 5 0 0 5 5 5 0 RNA polymerase I-specific transcription initiation factor Rrn7 C1_4 PF07975.7 ETO20513.1 - 0.059 13.3 18.8 3.3 7.7 0.3 4.5 2 1 2 4 4 4 0 TFIIH C1-like domain TF_Zn_Ribbon PF08271.7 ETO20513.1 - 0.42 9.9 4.6 0.29 10.4 0.4 2.7 3 0 0 3 3 3 0 TFIIB zinc-binding Fer2 PF00111.22 ETO20513.1 - 3.1 7.6 6.6 94 2.8 4.5 2.6 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain GAGA PF09237.6 ETO20513.1 - 4.7 6.8 26.1 1.1 8.9 0.1 5.1 3 1 3 6 6 6 0 GAGA factor IBR PF01485.16 ETO20513.1 - 5.4 6.9 20.2 0.089 12.6 1.4 3.6 2 1 0 2 2 2 0 IBR domain Ribosomal_L37ae PF01780.14 ETO20513.1 - 7.8 6.4 13.5 7.7 6.4 2.6 3.8 1 1 2 3 3 3 0 Ribosomal L37ae protein family Cytochrom_c3_2 PF14537.1 ETO20513.1 - 8.4 6.8 21.4 30 5.0 4.5 3.2 1 1 2 3 3 3 0 Cytochrome c3 Gemini_mov PF01708.11 ETO20514.1 - 0.00096 18.6 0.6 0.044 13.3 0.0 2.3 2 0 0 2 2 2 2 Geminivirus putative movement protein DUF4608 PF15381.1 ETO20517.1 - 0.04 14.0 0.1 0.085 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4608) Peptidase_U32 PF01136.14 ETO20517.1 - 0.044 12.6 0.3 0.25 10.2 0.1 2.0 2 0 0 2 2 2 0 Peptidase family U32 EVI2A PF05399.6 ETO20517.1 - 0.16 11.2 2.7 0.13 11.5 1.1 1.4 1 1 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Viral_coat PF00729.13 ETO20519.1 - 0.047 12.9 0.4 0.17 11.1 0.1 1.9 1 1 1 2 2 2 0 Viral coat protein (S domain) FdsD PF11390.3 ETO20519.1 - 0.13 12.3 0.7 16 5.7 0.1 2.6 2 0 0 2 2 2 0 NADH-dependant formate dehydrogenase delta subunit FdsD Latarcin PF10279.4 ETO20519.1 - 0.32 11.2 7.2 0.11 12.6 0.6 2.4 2 0 0 2 2 2 0 Latarcin precursor DUF1018 PF06252.7 ETO20519.1 - 0.43 11.1 5.4 12 6.4 0.0 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF1018) V_ATPase_I PF01496.14 ETO20520.1 - 8.1e-69 232.3 7.4 1.1e-68 231.9 5.1 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family WD40 PF00400.27 ETO20521.1 - 9.1e-58 190.2 13.7 2.5e-11 43.0 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO20521.1 - 6.3e-13 47.7 5.0 0.0027 15.8 0.1 5.7 2 2 3 6 6 6 5 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO20521.1 - 0.0019 18.5 7.8 0.0072 16.6 5.4 2.1 1 0 0 1 1 1 1 TRAF-type zinc finger Methyltransf_25 PF13649.1 ETO20521.1 - 0.076 13.3 0.0 25 5.3 0.0 2.9 3 0 0 3 3 3 0 Methyltransferase domain Plasmodium_Vir PF05795.6 ETO20524.1 - 0.021 14.0 0.9 0.031 13.4 0.6 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Vfa1 PF08432.5 ETO20524.1 - 0.043 13.8 6.7 0.06 13.3 4.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SURF6 PF04935.7 ETO20524.1 - 0.29 10.3 5.6 0.39 9.9 3.9 1.2 1 0 0 1 1 1 0 Surfeit locus protein 6 Daxx PF03344.10 ETO20524.1 - 2.1 6.7 22.2 2.6 6.4 15.4 1.2 1 0 0 1 1 1 0 Daxx Family Paf1 PF03985.8 ETO20524.1 - 4.1 6.0 17.3 6 5.4 12.0 1.3 1 0 0 1 1 1 0 Paf1 HEAT PF02985.17 ETO20525.1 - 0.00013 21.7 3.2 7.4 6.9 0.0 4.4 4 0 0 4 4 4 3 HEAT repeat DHC_N2 PF08393.8 ETO20527.1 - 1.2e-114 383.0 30.0 2.9e-61 207.1 0.3 3.0 2 1 1 3 3 3 2 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 ETO20527.1 - 5.9e-44 150.3 0.1 1.4e-43 149.1 0.1 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA PF00004.24 ETO20527.1 - 0.0009 19.4 0.7 0.026 14.7 0.1 3.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF651 PF04895.7 ETO20527.1 - 0.018 14.6 3.1 0.059 13.0 0.0 3.1 3 0 0 3 3 3 0 Archaeal protein of unknown function (DUF651) AAA_5 PF07728.9 ETO20527.1 - 0.021 14.5 0.0 0.4 10.4 0.0 2.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 ETO20527.1 - 0.023 15.4 1.2 0.12 13.1 0.1 2.8 2 1 0 2 2 2 0 AAA domain Baculo_PEP_N PF04512.7 ETO20527.1 - 0.027 14.4 0.5 0.52 10.3 0.0 3.3 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, N terminus RF-1 PF00472.15 ETO20527.1 - 0.031 14.0 2.9 0.079 12.7 0.2 2.5 2 0 0 2 2 2 0 RF-1 domain AAA_19 PF13245.1 ETO20527.1 - 0.042 13.6 0.2 0.12 12.1 0.2 1.7 1 0 0 1 1 1 0 Part of AAA domain HTH_1 PF00126.22 ETO20527.1 - 0.14 11.9 0.0 0.41 10.4 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family RNA_pol_Rpb2_2 PF04561.9 ETO20528.1 - 0.046 13.1 0.1 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 Zip PF02535.17 ETO20529.1 - 0.00094 18.2 6.4 0.0053 15.8 3.3 2.2 2 0 0 2 2 2 1 ZIP Zinc transporter Chordopox_G3 PF06129.7 ETO20529.1 - 0.023 14.8 0.1 0.12 12.5 0.1 2.3 1 0 0 1 1 1 0 Chordopoxvirus G3 protein HATPase_c_3 PF13589.1 ETO20530.1 - 0.01 15.4 0.6 0.023 14.3 0.1 1.7 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Taeniidae_ag PF05596.6 ETO20531.1 - 0.0083 15.9 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Taeniidae antigen CPSase_L_D2 PF02786.12 ETO20532.1 - 0.1 11.8 0.2 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain DHC_N1 PF08385.7 ETO20533.1 - 1.1e-72 245.3 28.3 6e-54 183.4 11.0 3.6 3 1 0 3 3 3 2 Dynein heavy chain, N-terminal region 1 DUF919 PF06034.6 ETO20533.1 - 0.0093 15.5 0.1 0.038 13.6 0.1 2.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF919) Sas10 PF09368.5 ETO20534.1 - 0.0097 16.0 6.4 0.0097 16.0 4.5 2.4 2 0 0 2 2 2 1 Sas10 C-terminal domain DUF3141 PF11339.3 ETO20534.1 - 0.042 12.1 0.6 0.051 11.9 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) Spc24 PF08286.6 ETO20534.1 - 0.14 11.8 8.5 0.2 11.3 5.9 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Astro_capsid PF03115.9 ETO20534.1 - 0.27 9.4 3.2 0.3 9.2 2.2 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Atg14 PF10186.4 ETO20534.1 - 3.4 6.5 8.9 3.7 6.4 6.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PEARLI-4 PF05278.7 ETO20534.1 - 3.7 6.8 13.7 4.7 6.5 9.5 1.3 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) APG17 PF04108.7 ETO20535.1 - 0.00017 20.5 0.2 0.00017 20.5 0.1 3.1 2 1 1 3 3 3 3 Autophagy protein Apg17 ABC2_membrane_5 PF13346.1 ETO20537.1 - 0.0065 15.7 4.8 0.013 14.8 3.3 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein DUF383 PF04063.9 ETO20539.1 - 0.017 14.6 2.9 0.055 12.9 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF383) FCD PF07729.7 ETO20539.1 - 0.046 14.0 1.6 0.084 13.2 0.1 2.1 2 0 0 2 2 2 0 FCD domain CENP-Q PF13094.1 ETO20539.1 - 7 6.6 14.6 1.2 9.1 6.6 2.3 3 1 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit ubiquitin PF00240.18 ETO20541.1 - 1.6e-09 36.9 0.1 2.8e-09 36.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 ETO20541.1 - 3.1e-06 26.7 0.1 5.8e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 ETO20541.1 - 0.00018 21.3 0.1 0.00041 20.1 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2847 PF11009.3 ETO20541.1 - 0.024 14.2 0.0 0.05 13.1 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2847) ADP_ribosyl_GH PF03747.9 ETO20543.1 - 2.4e-29 103.0 0.1 3.6e-28 99.1 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylglycohydrolase DUF914 PF06027.7 ETO20544.1 - 2.4e-33 115.4 2.9 5.4e-33 114.2 2.0 1.5 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 ETO20544.1 - 4.3e-07 29.1 0.6 9.1e-07 28.0 0.4 1.5 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 ETO20544.1 - 1.7e-05 24.8 2.3 1.7e-05 24.8 1.6 2.4 2 0 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 ETO20544.1 - 0.00021 21.4 0.8 0.00021 21.4 0.5 2.2 3 0 0 3 3 3 1 Multidrug resistance efflux transporter Beach PF02138.13 ETO20545.1 - 1.2e-91 306.8 0.0 2.4e-91 305.9 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 ETO20545.1 - 1.5e-09 37.6 2.0 1.8e-08 34.1 0.5 2.8 2 1 0 2 2 2 1 PH domain associated with Beige/BEACH WD40 PF00400.27 ETO20546.1 - 9.4e-25 85.5 19.0 3.3e-06 26.7 1.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 ETO20546.1 - 0.038 13.7 0.1 3.4 7.4 0.0 3.4 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Senescence_reg PF04520.8 ETO20546.1 - 0.068 13.6 3.5 0.14 12.6 2.4 1.6 1 0 0 1 1 1 0 Senescence regulator ACBP PF00887.14 ETO20547.1 - 5.9e-13 48.3 0.1 1.4e-12 47.0 0.1 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein Acetyltransf_1 PF00583.19 ETO20547.1 - 4.2e-06 26.6 0.0 9.6e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 ETO20547.1 - 2.1e-05 24.1 0.0 4.8e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 ETO20547.1 - 0.021 14.9 0.0 0.072 13.2 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 ETO20547.1 - 0.056 13.6 0.4 0.16 12.1 0.3 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETO20547.1 - 0.1 12.4 0.0 7.5 6.4 0.0 3.0 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Tn7_Tnp_TnsA_N PF08722.6 ETO20548.1 - 0.14 12.2 1.9 0.16 11.9 0.9 1.4 1 1 0 1 1 1 0 TnsA endonuclease N terminal V-SNARE PF05008.10 ETO20548.1 - 0.17 12.0 10.1 0.064 13.4 4.8 1.9 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF1395 PF07160.7 ETO20548.1 - 0.61 9.5 10.4 0.63 9.5 7.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1395) MIP PF00230.15 ETO20549.1 - 0.00012 21.5 5.6 0.00064 19.2 4.0 1.7 1 1 0 1 1 1 1 Major intrinsic protein DUF4203 PF13886.1 ETO20549.1 - 0.031 13.7 4.0 0.037 13.4 2.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) Pneumo_att_G PF05539.6 ETO20550.1 - 0.015 14.6 2.5 0.019 14.3 1.7 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G RGS PF00615.14 ETO20550.1 - 0.032 14.3 0.4 0.074 13.1 0.2 1.6 1 0 0 1 1 1 0 Regulator of G protein signaling domain Peptidase_G2 PF11962.3 ETO20552.1 - 0.037 13.1 0.1 0.23 10.5 0.3 1.8 2 0 0 2 2 2 0 Peptidase_G2, IMC autoproteolytic cleavage domain TEP1_N PF05386.6 ETO20553.1 - 0.076 12.4 0.3 0.17 11.3 0.2 1.6 1 0 0 1 1 1 0 TEP1 N-terminal domain MAGP PF05507.6 ETO20553.1 - 0.53 10.1 3.6 0.29 10.9 0.1 2.1 2 0 0 2 2 2 0 Microfibril-associated glycoprotein (MAGP) 7tm_1 PF00001.16 ETO20554.1 - 0.0069 15.5 1.2 0.0097 15.0 0.6 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3899 PF13038.1 ETO20555.1 - 0.49 10.5 14.7 1.7 8.8 6.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3899) SecY PF00344.15 ETO20555.1 - 1.1 8.1 6.1 3.3 6.5 3.4 1.9 1 1 1 2 2 2 0 SecY translocase TPR_11 PF13414.1 ETO20556.1 - 1.6e-16 59.7 6.1 2.4e-08 33.4 0.1 4.4 2 2 1 4 4 4 3 TPR repeat TPR_1 PF00515.23 ETO20556.1 - 5.3e-12 44.8 7.1 0.0018 17.7 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO20556.1 - 9.7e-12 44.1 5.4 0.23 11.7 0.0 5.8 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO20556.1 - 1.3e-10 40.2 18.4 0.0019 17.9 0.0 7.3 6 1 1 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO20556.1 - 6.4e-08 32.4 5.1 2.7e-05 24.0 0.2 4.4 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO20556.1 - 1e-07 31.9 1.6 0.52 11.1 0.0 5.3 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO20556.1 - 1.6e-07 30.6 4.7 0.093 12.5 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO20556.1 - 9.6e-07 29.3 0.0 0.00058 20.4 0.0 4.6 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO20556.1 - 1.9e-06 27.9 1.9 0.15 12.5 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO20556.1 - 5e-06 26.7 3.1 0.13 12.5 0.0 4.2 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETO20556.1 - 0.00027 20.7 0.2 0.061 13.1 0.0 3.4 2 1 2 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO20556.1 - 0.00028 20.9 1.1 0.00028 20.9 0.8 2.9 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 ETO20556.1 - 0.013 14.5 1.9 0.78 8.7 0.1 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF3340 PF11818.3 ETO20557.1 - 1.9 8.4 12.5 2.4 8.1 8.7 1.2 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) DUF3987 PF13148.1 ETO20557.1 - 2.1 6.8 9.9 2 6.8 6.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) U79_P34 PF03064.11 ETO20557.1 - 2.1 7.7 14.2 2.4 7.5 9.8 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RPOL_N PF14700.1 ETO20557.1 - 2.3 7.3 11.2 2.2 7.4 7.8 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal Serinc PF03348.10 ETO20557.1 - 4.1 6.0 5.5 4 6.0 3.8 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) YqfQ PF14181.1 ETO20557.1 - 4.2 7.3 15.1 5.1 7.1 10.5 1.2 1 0 0 1 1 1 0 YqfQ-like protein DUF4337 PF14235.1 ETO20557.1 - 4.7 7.0 10.4 5.7 6.7 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Peptidase_U57 PF05582.7 ETO20557.1 - 8.1 5.3 8.9 7.9 5.3 6.2 1.2 1 0 0 1 1 1 0 YabG peptidase U57 DUF2413 PF10310.4 ETO20557.1 - 8.4 5.0 13.5 8.2 5.1 9.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) TPR_12 PF13424.1 ETO20558.1 - 7.2e-20 70.7 0.7 1.3e-14 53.8 0.0 2.4 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO20558.1 - 8.7e-08 31.6 4.4 2.7e-05 23.7 0.4 2.4 2 0 0 2 2 2 2 TPR repeat TPR_7 PF13176.1 ETO20558.1 - 0.00029 20.4 0.6 9 6.3 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO20558.1 - 0.00069 19.4 0.0 0.02 14.8 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO20558.1 - 0.035 14.2 8.7 5.1 7.5 0.1 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETO20558.1 - 0.055 13.0 15.9 0.64 9.7 0.3 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETO20558.1 - 0.26 11.2 9.5 1.7 8.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETO20558.1 - 1.4 8.8 7.6 7.8 6.5 0.4 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat PBP1_TM PF14812.1 ETO20560.1 - 0.0008 19.6 4.7 0.0008 19.6 3.3 3.5 3 0 0 3 3 3 2 Transmembrane domain of transglycosylase PBP1 at N-terminal Zip PF02535.17 ETO20560.1 - 0.44 9.5 8.0 0.58 9.1 0.5 2.7 3 0 0 3 3 3 0 ZIP Zinc transporter DUF912 PF06024.7 ETO20560.1 - 4.4 7.4 0.0 4.4 7.4 0.0 3.9 4 0 0 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CobT PF06213.7 ETO20562.1 - 0.44 9.6 3.4 0.5 9.4 2.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT HAMP PF00672.20 ETO20563.1 - 0.068 13.3 0.5 0.26 11.4 0.0 1.9 2 0 0 2 2 2 0 HAMP domain YqaJ PF09588.5 ETO20564.1 - 7.8e-08 32.4 0.0 1.7e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain zf-AN1 PF01428.11 ETO20566.1 - 0.0048 16.7 0.9 0.011 15.6 0.7 1.6 1 0 0 1 1 1 1 AN1-like Zinc finger zf-TRAF PF02176.13 ETO20568.1 - 2.9e-06 27.5 6.5 9.8e-06 25.8 4.5 2.0 1 0 0 1 1 1 1 TRAF-type zinc finger DUF3021 PF11457.3 ETO20568.1 - 0.013 15.3 8.4 0.026 14.3 5.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) Herpes_BLRF2 PF05812.7 ETO20568.1 - 0.28 10.9 1.8 0.58 9.9 1.3 1.4 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Mo25 PF08569.6 ETO20569.1 - 0.0033 16.4 0.2 0.006 15.6 0.1 1.3 1 0 0 1 1 1 1 Mo25-like HEAT_2 PF13646.1 ETO20569.1 - 0.0051 17.0 0.1 0.085 13.1 0.0 2.3 2 0 0 2 2 2 1 HEAT repeats ENTH PF01417.15 ETO20569.1 - 0.029 14.2 0.7 0.62 9.9 0.0 2.6 3 0 0 3 3 3 0 ENTH domain Cas_NE0113 PF09623.5 ETO20573.1 - 0.0076 15.7 0.0 0.009 15.4 0.0 1.1 1 0 0 1 1 1 1 CRISPR-associated protein NE0113 (Cas_NE0113) ALIX_LYPXL_bnd PF13949.1 ETO20574.1 - 0.00098 18.1 2.2 0.1 11.5 0.0 2.2 1 1 1 2 2 2 2 ALIX V-shaped domain binding to HIV PXA PF02194.10 ETO20574.1 - 1.3 8.5 5.7 2.4 7.7 3.9 1.6 1 1 0 1 1 1 0 PXA domain Nup54 PF13874.1 ETO20575.1 - 0.0034 17.0 3.6 0.006 16.2 2.5 1.3 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 bZIP_2 PF07716.10 ETO20575.1 - 0.0061 16.3 0.5 0.0061 16.3 0.4 3.2 2 1 1 3 3 3 1 Basic region leucine zipper Tropomyosin PF00261.15 ETO20575.1 - 0.0063 15.6 8.0 0.01 14.9 5.5 1.3 1 0 0 1 1 1 1 Tropomyosin APG6 PF04111.7 ETO20575.1 - 0.0096 14.9 4.4 0.014 14.4 3.1 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 IncA PF04156.9 ETO20575.1 - 0.048 13.2 5.5 0.064 12.8 3.8 1.2 1 0 0 1 1 1 0 IncA protein Tropomyosin_1 PF12718.2 ETO20575.1 - 0.093 12.5 7.6 0.12 12.2 4.4 1.7 1 1 0 1 1 1 0 Tropomyosin like DUF904 PF06005.7 ETO20575.1 - 0.85 9.9 6.6 3 8.2 4.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF972 PF06156.8 ETO20575.1 - 1.5 9.2 7.1 7.3 6.9 3.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) PspA_IM30 PF04012.7 ETO20575.1 - 1.9 7.7 10.3 1.9 7.8 2.0 2.1 1 1 0 2 2 2 0 PspA/IM30 family CENP-H PF05837.7 ETO20575.1 - 2.6 8.2 8.9 4.2 7.5 2.1 2.7 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DivIC PF04977.10 ETO20575.1 - 5 6.6 7.3 1.5 8.3 0.7 2.5 1 1 1 2 2 2 0 Septum formation initiator ADIP PF11559.3 ETO20575.1 - 7.5 6.4 13.3 1.6 8.5 5.8 2.2 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding D123 PF07065.9 ETO20576.1 - 0.0013 17.8 1.3 0.0019 17.3 0.5 1.6 1 1 0 1 1 1 1 D123 DUF1779 PF08680.5 ETO20576.1 - 0.17 11.7 5.9 0.33 10.7 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1779) Spore_coat_CotO PF14153.1 ETO20577.1 - 0.046 13.1 6.0 0.05 13.0 4.2 1.1 1 0 0 1 1 1 0 Spore coat protein CotO PAXIP1_C PF15364.1 ETO20577.1 - 0.12 12.2 8.5 0.13 12.1 5.9 1.1 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein THRAP3_BCLAF1 PF15440.1 ETO20577.1 - 0.13 10.9 9.1 0.13 10.9 6.3 1.0 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Rhabdo_ncap PF00945.13 ETO20577.1 - 0.18 10.3 3.9 0.2 10.2 2.7 1.0 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein FAM176 PF14851.1 ETO20577.1 - 0.39 10.3 4.9 0.43 10.2 3.4 1.1 1 0 0 1 1 1 0 FAM176 family Tim54 PF11711.3 ETO20577.1 - 0.42 9.1 4.4 0.43 9.1 3.1 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 HSP90 PF00183.13 ETO20577.1 - 0.94 7.7 9.8 1.1 7.6 6.8 1.0 1 0 0 1 1 1 0 Hsp90 protein FLO_LFY PF01698.11 ETO20577.1 - 1.1 8.0 5.2 1.1 8.0 3.6 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Sec62 PF03839.11 ETO20577.1 - 2.9 7.2 5.9 3.2 7.0 4.1 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4611 PF15387.1 ETO20577.1 - 3.1 7.9 10.1 2.5 8.3 6.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) CDC45 PF02724.9 ETO20577.1 - 4.6 5.1 8.4 4.9 5.0 5.9 1.0 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.27 ETO20579.1 - 1.3e-39 132.6 3.1 4.2e-14 51.7 0.2 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat eIF2A PF08662.6 ETO20579.1 - 6.2e-08 32.5 0.1 3.1e-05 23.7 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO20579.1 - 5.5e-07 29.1 2.6 0.87 9.3 0.2 4.2 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO20579.1 - 2.5e-05 22.6 2.3 0.04 12.0 0.1 2.9 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Proteasome_A_N PF10584.4 ETO20579.1 - 0.00027 20.1 3.9 4.4 6.7 0.0 4.8 5 0 0 5 5 5 1 Proteasome subunit A N-terminal signature DUF1258 PF06869.7 ETO20579.1 - 0.0059 15.7 0.1 0.032 13.3 0.1 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1258) DPPIV_N PF00930.16 ETO20579.1 - 0.0096 14.5 0.0 0.35 9.4 0.0 2.7 2 2 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nbas_N PF15492.1 ETO20579.1 - 0.02 13.9 0.3 4.1 6.4 0.0 2.9 1 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Coatomer_WDAD PF04053.9 ETO20579.1 - 0.027 13.2 0.0 0.099 11.4 0.0 1.7 1 1 0 1 1 1 0 Coatomer WD associated region Str_synth PF03088.11 ETO20579.1 - 0.094 12.7 0.0 0.77 9.8 0.0 2.4 2 2 1 3 3 3 0 Strictosidine synthase Nucleoporin_N PF08801.6 ETO20579.1 - 0.12 11.0 0.4 0.23 10.1 0.2 1.7 1 1 0 1 1 1 0 Nup133 N terminal like Spore_III_AF PF09581.5 ETO20580.1 - 0.031 14.1 1.3 0.034 13.9 0.9 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) MMtag PF10159.4 ETO20580.1 - 0.11 12.4 2.6 3.3 7.7 0.1 2.1 2 0 0 2 2 2 0 Kinase phosphorylation protein KRAB PF01352.22 ETO20580.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 KRAB box DCAF15_WD40 PF14939.1 ETO20581.1 - 0.052 12.9 0.9 0.075 12.3 0.6 1.2 1 0 0 1 1 1 0 DDB1-and CUL4-substrate receptor 15, WD repeat ANTH PF07651.11 ETO20582.1 - 7.9e-13 47.7 0.2 1.2e-12 47.1 0.1 1.2 1 1 0 1 1 1 1 ANTH domain ENTH PF01417.15 ETO20582.1 - 8.5e-06 25.6 0.0 1.5e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 ENTH domain REJ PF02010.10 ETO20583.1 - 1.8e-09 36.4 0.1 2.9e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 REJ domain PhnA_Zn_Ribbon PF08274.7 ETO20583.1 - 0.022 14.5 1.6 0.18 11.5 0.1 2.4 2 0 0 2 2 2 0 PhnA Zinc-Ribbon WD40 PF00400.27 ETO20584.1 - 1.9e-86 281.1 24.5 5.6e-14 51.3 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO20584.1 - 1.5e-11 44.3 0.4 3.2e-05 23.7 0.1 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO20584.1 - 2.9e-07 28.9 3.4 0.85 7.6 0.0 5.0 1 1 3 5 5 5 4 Nucleoporin Nup120/160 PD40 PF07676.7 ETO20584.1 - 7.8e-07 28.6 7.3 20 4.9 0.0 6.9 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO20584.1 - 2.2e-06 26.6 9.2 0.17 10.6 0.1 5.1 1 1 4 5 5 5 3 Nup133 N terminal like Coatomer_WDAD PF04053.9 ETO20584.1 - 0.0003 19.6 0.3 0.35 9.6 0.1 2.2 1 1 1 2 2 2 2 Coatomer WD associated region DUF1258 PF06869.7 ETO20584.1 - 0.0004 19.5 2.8 2.3 7.2 0.0 3.6 1 1 1 3 3 3 2 Protein of unknown function (DUF1258) Cytochrom_D1 PF02239.11 ETO20584.1 - 0.0011 17.2 0.1 0.077 11.2 0.0 2.7 1 1 2 3 3 3 1 Cytochrome D1 heme domain Resistin PF06954.6 ETO20584.1 - 0.038 14.2 9.2 2.2 8.5 0.2 5.3 1 1 4 6 6 6 0 Resistin AcetylCoA_hyd_C PF13336.1 ETO20584.1 - 0.076 12.6 0.0 2.8 7.6 0.0 2.7 3 0 0 3 3 3 0 Acetyl-CoA hydrolase/transferase C-terminal domain SGL PF08450.7 ETO20584.1 - 0.099 12.0 0.3 5.7 6.2 0.0 2.8 1 1 2 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region WD40 PF00400.27 ETO20585.1 - 1.4e-25 88.2 18.5 0.00022 21.0 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat PD40 PF07676.7 ETO20585.1 - 8.6e-05 22.1 1.3 0.059 13.0 0.0 4.8 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO20585.1 - 0.00016 20.1 0.9 0.037 12.3 0.0 2.9 1 1 2 3 3 3 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO20585.1 - 0.00041 19.8 1.1 0.002 17.6 0.3 2.1 1 1 1 2 2 2 1 PQQ-like domain Me-amine-dh_H PF06433.6 ETO20585.1 - 0.0018 16.9 0.0 0.036 12.7 0.0 2.4 2 0 0 2 2 2 1 Methylamine dehydrogenase heavy chain (MADH) DPPIV_N PF00930.16 ETO20585.1 - 0.0081 14.7 0.1 1.5 7.3 0.0 3.4 1 1 3 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Surfac_D-trimer PF09006.6 ETO20585.1 - 0.01 15.5 0.0 0.83 9.4 0.0 2.4 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Str_synth PF03088.11 ETO20585.1 - 0.15 12.1 1.2 16 5.5 0.0 3.8 2 1 2 4 4 4 0 Strictosidine synthase Kelch_1 PF01344.20 ETO20586.1 - 5.3e-08 32.2 7.0 6.5e-06 25.6 0.3 3.5 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO20586.1 - 6.2e-07 29.3 3.5 0.00096 19.2 0.2 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO20586.1 - 2e-06 27.6 1.7 0.001 18.9 0.7 3.6 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 ETO20586.1 - 0.0015 18.2 8.8 0.01 15.5 0.4 4.3 5 1 0 5 5 5 1 Kelch motif Kelch_3 PF13415.1 ETO20586.1 - 0.0019 18.2 0.0 0.13 12.4 0.0 3.5 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO20586.1 - 0.0031 17.2 0.1 0.051 13.3 0.0 2.8 2 0 0 2 2 2 1 Galactose oxidase, central domain WD40 PF00400.27 ETO20587.1 - 1.9e-56 186.0 15.1 4.2e-11 42.2 0.1 7.7 7 1 1 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO20587.1 - 4.9e-06 24.9 4.5 0.019 13.1 1.7 3.6 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO20587.1 - 0.019 14.8 0.3 3.8 7.5 0.0 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF3601) DUF2415 PF10313.4 ETO20587.1 - 0.074 12.7 0.0 0.58 9.8 0.0 2.4 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) NPV_P10 PF05531.7 ETO20588.1 - 0.0062 16.7 6.4 0.094 12.9 1.5 3.3 2 1 1 3 3 3 1 Nucleopolyhedrovirus P10 protein SPX PF03105.14 ETO20588.1 - 0.18 11.5 13.4 0.28 10.9 7.0 2.0 1 1 1 2 2 2 0 SPX domain DUF892 PF05974.7 ETO20588.1 - 0.37 10.5 5.1 0.11 12.2 1.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF892) DUF948 PF06103.6 ETO20588.1 - 0.57 10.0 3.5 1.1 9.2 0.9 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) MbeD_MobD PF04899.7 ETO20588.1 - 0.59 10.0 2.9 1.1 9.2 0.6 2.3 2 0 0 2 2 2 0 MbeD/MobD like DUF2203 PF09969.4 ETO20588.1 - 5.2 7.3 6.3 1.6 8.9 0.5 2.5 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) V_ATPase_I PF01496.14 ETO20588.1 - 9.6 3.9 14.7 0.47 8.2 3.6 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Daxx PF03344.10 ETO20589.1 - 0.011 14.2 12.2 0.014 13.8 8.4 1.1 1 0 0 1 1 1 0 Daxx Family Interfer-bind PF09294.5 ETO20589.1 - 0.02 14.8 0.7 0.15 12.1 0.0 2.4 2 1 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.16 ETO20589.1 - 0.064 13.3 0.0 0.15 12.1 0.0 1.8 2 0 0 2 2 2 0 Fibronectin type III domain CDC45 PF02724.9 ETO20589.1 - 1.8 6.4 10.9 2.5 6.0 7.6 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 ETO20589.1 - 7.4 5.1 20.0 11 4.6 13.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) ETRAMP PF09716.5 ETO20590.1 - 0.002 18.0 0.2 1.1 9.2 0.0 4.3 1 1 1 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) AATF-Che1 PF13339.1 ETO20591.1 - 8.1e-14 51.8 3.0 8.1e-14 51.8 2.1 4.1 3 3 1 4 4 4 1 Apoptosis antagonizing transcription factor TRAUB PF08164.7 ETO20591.1 - 3.4e-07 30.2 0.4 3.4e-07 30.2 0.3 3.6 3 1 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AAA_8 PF12780.2 ETO20593.1 - 3.2e-47 160.7 0.2 1e-46 159.0 0.2 1.7 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 Kelch_6 PF13964.1 ETO20594.1 - 0.00028 20.9 0.0 0.0014 18.7 0.0 2.1 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.1 ETO20594.1 - 0.00079 19.1 1.9 0.045 13.5 0.0 3.4 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO20594.1 - 0.0022 18.1 0.0 0.0055 16.8 0.0 1.7 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO20594.1 - 0.0022 17.4 0.1 0.019 14.4 0.0 2.4 2 0 0 2 2 2 1 Kelch motif DUF4011 PF13195.1 ETO20596.1 - 0.022 14.7 6.5 0.034 14.1 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) DUF1682 PF07946.9 ETO20596.1 - 0.03 13.1 8.6 0.052 12.3 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PVL_ORF50 PF07768.6 ETO20596.1 - 0.079 12.9 5.4 0.14 12.1 3.8 1.4 1 0 0 1 1 1 0 PVL ORF-50-like family TRAP_alpha PF03896.11 ETO20596.1 - 0.11 11.5 7.1 0.12 11.3 4.1 1.7 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Serinc PF03348.10 ETO20596.1 - 0.15 10.7 3.7 0.21 10.2 2.6 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Spore_coat_CotO PF14153.1 ETO20596.1 - 0.46 9.8 16.4 0.79 9.1 11.3 1.3 1 0 0 1 1 1 0 Spore coat protein CotO CAF-1_p150 PF11600.3 ETO20596.1 - 0.52 9.6 27.8 0.014 14.7 14.5 1.7 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2201_N PF13203.1 ETO20596.1 - 0.73 8.9 7.2 1.3 8.0 5.0 1.5 1 0 0 1 1 1 0 Putative metallopeptidase domain UPF0118 PF01594.11 ETO20596.1 - 0.98 8.3 3.5 1.4 7.8 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF20 Tim54 PF11711.3 ETO20596.1 - 1.1 7.7 11.0 1.7 7.1 7.6 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RR_TM4-6 PF06459.7 ETO20596.1 - 1.4 8.7 15.9 2.3 8.0 11.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TT_ORF1 PF02956.9 ETO20596.1 - 2.3 6.5 11.6 3 6.2 8.0 1.1 1 0 0 1 1 1 0 TT viral orf 1 PBP_sp32 PF07222.7 ETO20596.1 - 4.1 6.5 16.9 7 5.7 11.7 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Presenilin PF01080.12 ETO20596.1 - 5.5 5.7 14.3 8.8 5.0 9.9 1.3 1 0 0 1 1 1 0 Presenilin Sec62 PF03839.11 ETO20596.1 - 5.6 6.3 7.3 8.7 5.6 5.1 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 TEX19 PF15553.1 ETO20596.1 - 6.9 6.5 9.8 16 5.3 6.8 1.6 1 0 0 1 1 1 0 Testis-expressed protein 19 E1_dh PF00676.15 ETO20597.1 - 9.5e-12 44.2 0.0 1.2e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component AAA_25 PF13481.1 ETO20597.1 - 0.013 14.9 0.0 0.028 13.8 0.0 1.5 2 0 0 2 2 2 0 AAA domain Abhydrolase_6 PF12697.2 ETO20598.1 - 0.0005 20.0 0.0 0.0005 20.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3911 PF13050.1 ETO20598.1 - 0.098 12.7 0.5 4.9 7.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3911) TPPK_C PF12555.3 ETO20599.1 - 0.35 10.6 4.3 0.95 9.2 3.0 1.7 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Ribosomal_60s PF00428.14 ETO20599.1 - 0.95 9.9 10.5 2 8.8 7.3 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3157 PF11355.3 ETO20599.1 - 1.8 7.7 5.4 0.18 11.0 0.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3157) cNMP_binding PF00027.24 ETO20602.1 - 7.1e-35 118.7 0.0 1e-17 63.7 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain HAUS5 PF14817.1 ETO20603.1 - 0.013 14.1 4.3 0.015 13.8 3.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Tet_JBP PF12851.2 ETO20603.1 - 0.015 14.6 1.7 0.029 13.6 1.2 1.5 1 1 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily EssA PF10661.4 ETO20603.1 - 0.027 14.1 4.4 0.042 13.5 3.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA RPA_interact_M PF14767.1 ETO20603.1 - 0.042 14.5 1.2 11 6.8 0.1 2.3 2 0 0 2 2 2 0 Replication protein A interacting middle Apolipoprotein PF01442.13 ETO20603.1 - 0.046 13.2 3.2 0.069 12.6 2.2 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain LUC7 PF03194.10 ETO20603.1 - 0.049 13.1 5.4 0.062 12.8 3.7 1.1 1 0 0 1 1 1 0 LUC7 N_terminus eIF-4B PF06273.6 ETO20603.1 - 0.073 11.8 2.2 0.095 11.4 1.5 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B SHS2_FTSA PF02491.15 ETO20603.1 - 0.11 12.4 0.3 0.24 11.3 0.1 1.7 1 1 0 1 1 1 0 SHS2 domain inserted in FTSA Med9 PF07544.8 ETO20603.1 - 0.26 11.0 8.8 0.8 9.4 3.6 2.9 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Exonuc_VII_L PF02601.10 ETO20603.1 - 0.4 9.8 6.2 0.47 9.5 4.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Med4 PF10018.4 ETO20603.1 - 1 8.7 6.6 1.6 8.1 4.6 1.3 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Sds3 PF08598.6 ETO20603.1 - 3.8 6.9 10.4 9.3 5.7 7.2 1.8 1 1 0 1 1 1 0 Sds3-like Fib_alpha PF08702.5 ETO20603.1 - 7.6 6.6 11.5 21 5.2 7.9 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family GTP_EFTU PF00009.22 ETO20604.1 - 4.9e-32 110.8 0.5 3.1e-31 108.2 0.3 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 ETO20604.1 - 8.9e-07 28.7 0.2 3.5e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.18 ETO20604.1 - 2.6e-06 27.3 0.0 9.5e-06 25.5 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 ETO20604.1 - 0.00095 19.6 0.6 0.0032 17.9 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Ras PF00071.17 ETO20604.1 - 0.0012 18.2 0.1 0.0036 16.6 0.1 1.8 1 0 0 1 1 1 1 Ras family FeoB_N PF02421.13 ETO20604.1 - 0.0036 16.6 0.0 0.0085 15.3 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 ETO20604.1 - 0.0068 15.6 1.8 0.013 14.7 0.0 2.3 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit FAM176 PF14851.1 ETO20604.1 - 4.4 6.9 11.4 2.2 7.9 0.3 3.8 4 0 0 4 4 4 0 FAM176 family Dynamin_N PF00350.18 ETO20604.1 - 4.6 7.0 8.9 0.3 10.8 0.2 3.5 2 2 0 2 2 2 0 Dynamin family WD40 PF00400.27 ETO20605.1 - 2.2e-12 46.3 6.1 3.3e-05 23.5 0.1 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat Pkinase PF00069.20 ETO20606.1 - 6.4e-69 231.9 0.6 8.7e-69 231.5 0.4 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO20606.1 - 2.6e-35 121.7 0.2 3.6e-35 121.2 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 ETO20606.1 - 3.1e-05 24.0 0.3 9.5e-05 22.5 0.2 1.9 1 0 0 1 1 1 1 PH domain APH PF01636.18 ETO20606.1 - 0.0001 22.1 0.0 0.00059 19.6 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 ETO20606.1 - 0.00028 20.2 0.1 0.0018 17.6 0.0 2.2 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kdo PF06293.9 ETO20606.1 - 0.015 14.3 0.0 0.03 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TBPIP PF07106.8 ETO20607.1 - 0.025 14.1 11.1 0.031 13.8 7.7 1.0 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TAN PF11640.3 ETO20607.1 - 0.03 14.0 2.9 0.034 13.8 2.0 1.2 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair DUF4050 PF13259.1 ETO20607.1 - 0.074 12.9 0.6 0.082 12.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) CENP-F_leu_zip PF10473.4 ETO20607.1 - 0.09 12.6 10.9 0.13 12.1 7.6 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.7 ETO20607.1 - 0.11 12.2 2.3 0.16 11.7 1.6 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mnd1 PF03962.10 ETO20607.1 - 0.14 11.8 6.2 0.16 11.6 4.3 1.1 1 0 0 1 1 1 0 Mnd1 family DUF342 PF03961.8 ETO20607.1 - 0.15 10.4 8.1 0.17 10.2 5.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PEP-utilisers_N PF05524.8 ETO20607.1 - 0.17 11.7 1.3 0.2 11.4 0.9 1.1 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Baculo_p24 PF05073.7 ETO20607.1 - 0.22 11.0 4.7 0.26 10.8 3.2 1.1 1 0 0 1 1 1 0 Baculovirus P24 capsid protein Spc24 PF08286.6 ETO20607.1 - 0.24 11.0 7.9 0.068 12.8 2.7 1.8 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 CALCOCO1 PF07888.6 ETO20607.1 - 0.27 9.4 8.6 0.32 9.2 5.9 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Phage_GPO PF05929.6 ETO20607.1 - 0.27 10.4 2.3 0.31 10.2 1.6 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Hrs_helical PF12210.3 ETO20607.1 - 0.29 11.4 3.8 0.38 11.0 2.6 1.2 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Img2 PF05046.9 ETO20607.1 - 0.47 10.7 2.7 0.6 10.3 1.8 1.4 1 1 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) COG2 PF06148.6 ETO20607.1 - 0.57 10.0 6.6 5.4 6.8 0.2 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Cortex-I_coil PF09304.5 ETO20607.1 - 0.7 9.9 9.8 0.82 9.7 6.6 1.3 1 1 0 1 1 1 0 Cortexillin I, coiled coil IncA PF04156.9 ETO20607.1 - 1.6 8.3 11.9 1.7 8.1 8.2 1.1 1 0 0 1 1 1 0 IncA protein FlaC_arch PF05377.6 ETO20607.1 - 1.6 8.6 6.4 3.6 7.5 1.9 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) COX16 PF14138.1 ETO20607.1 - 1.8 8.8 5.0 1.4 9.1 2.2 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 TPD52 PF04201.10 ETO20607.1 - 7 6.3 9.2 9.5 5.9 1.4 2.1 1 1 1 2 2 2 0 Tumour protein D52 family Sds3 PF08598.6 ETO20607.1 - 9.3 5.7 11.8 15 5.0 8.3 1.3 1 1 0 1 1 1 0 Sds3-like DUF4518 PF15008.1 ETO20608.1 - 0.073 12.0 0.5 0.085 11.8 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) TM231 PF10149.4 ETO20608.1 - 0.48 9.3 2.5 0.47 9.4 1.5 1.3 1 1 0 1 1 1 0 Transmembrane protein 231 DUF3915 PF13054.1 ETO20609.1 - 0.074 12.9 0.7 0.49 10.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) DUF4136 PF13590.1 ETO20609.1 - 0.22 11.5 2.4 1.8 8.5 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4136) LuxC PF05893.9 ETO20609.1 - 0.71 8.5 5.5 3.7 6.1 0.5 2.8 2 1 1 3 3 3 0 Acyl-CoA reductase (LuxC) CENP-K PF11802.3 ETO20609.1 - 2.4 7.3 12.7 1.1 8.3 1.4 2.0 2 0 0 2 2 2 0 Centromere-associated protein K WD40 PF00400.27 ETO20610.1 - 7.7e-62 203.1 31.8 1.1e-11 44.0 0.0 7.3 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO20610.1 - 4.7e-10 38.2 7.6 0.00045 18.4 0.1 5.1 1 1 3 5 5 5 4 Nucleoporin Nup120/160 UPF0118 PF01594.11 ETO20610.1 - 0.15 11.0 1.6 0.24 10.3 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF20 Kelch_6 PF13964.1 ETO20611.1 - 0.0046 17.0 0.1 0.63 10.3 0.0 3.6 3 0 0 3 3 3 1 Kelch motif TetR PF13972.1 ETO20612.1 - 0.0019 17.6 5.9 0.0023 17.3 1.0 2.5 2 0 0 2 2 2 1 Bacterial transcriptional repressor MbeD_MobD PF04899.7 ETO20612.1 - 0.12 12.3 6.1 0.33 10.8 4.2 1.8 1 0 0 1 1 1 0 MbeD/MobD like SseC PF04888.7 ETO20612.1 - 0.22 10.8 0.0 0.22 10.8 0.0 3.4 4 0 0 4 4 4 0 Secretion system effector C (SseC) like family DUF3618 PF12277.3 ETO20612.1 - 0.84 9.7 5.0 8 6.5 1.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) Kei1 PF08552.6 ETO20612.1 - 2.8 7.5 0.0 2.8 7.5 0.0 3.4 3 1 1 4 4 4 0 Inositolphosphorylceramide synthase subunit Kei1 60KD_IMP PF02096.15 ETO20612.1 - 5.8 6.5 8.9 13 5.3 4.9 2.4 2 1 0 2 2 2 0 60Kd inner membrane protein Ferric_reduct PF01794.14 ETO20614.1 - 0.00017 21.6 8.9 0.00017 21.6 6.2 2.5 2 1 0 2 2 2 1 Ferric reductase like transmembrane component Apis_Csd PF11671.3 ETO20614.1 - 0.015 15.0 7.0 0.025 14.3 4.9 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein DUF2976 PF11190.3 ETO20614.1 - 1.3 8.6 5.9 0.15 11.6 0.5 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) DUF4064 PF13273.1 ETO20614.1 - 2.4 8.3 5.0 11 6.1 0.0 3.3 2 2 0 3 3 3 0 Protein of unknown function (DUF4064) DUF4598 PF15370.1 ETO20615.1 - 0.12 12.6 4.6 0.15 12.3 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4598) BSP_II PF05432.6 ETO20615.1 - 0.46 9.7 10.0 0.48 9.6 6.9 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) SDA1 PF05285.7 ETO20615.1 - 1.8 7.7 11.3 1.8 7.7 7.8 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 ETO20615.1 - 2.2 6.1 4.9 2 6.2 3.4 1.0 1 0 0 1 1 1 0 Nop14-like family Zip PF02535.17 ETO20616.1 - 2.1 7.2 5.4 3.1 6.7 3.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF605 PF04652.11 ETO20617.1 - 0.033 13.5 19.5 0.052 12.9 13.5 1.2 1 0 0 1 1 1 0 Vta1 like RabGAP-TBC PF00566.13 ETO20618.1 - 3e-11 43.2 2.7 3e-11 43.2 1.9 3.8 3 1 1 4 4 4 1 Rab-GTPase-TBC domain PH PF00169.24 ETO20618.1 - 0.0037 17.4 0.4 0.0037 17.4 0.2 3.2 3 2 0 3 3 3 1 PH domain tRNA-synt_2 PF00152.15 ETO20619.1 - 2.2e-39 135.1 0.1 2.2e-39 135.1 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 ETO20619.1 - 4.6e-11 42.4 0.1 1e-10 41.2 0.0 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 ETO20619.1 - 0.00054 19.5 0.1 0.038 13.5 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.15 ETO20619.1 - 0.0011 18.2 0.0 0.0045 16.2 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 ETO20620.1 - 1.3e-23 83.3 0.0 1.4e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) RasGEF_N PF00618.15 ETO20620.1 - 0.068 13.2 0.3 0.14 12.2 0.2 1.5 1 1 0 1 1 1 0 RasGEF N-terminal motif Abhydrolase_3 PF07859.8 ETO20621.1 - 5.8e-13 48.9 0.0 7e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 ETO20621.1 - 2.8e-05 22.9 0.1 3.5e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 ETO20621.1 - 0.077 12.2 0.0 0.59 9.3 0.0 1.9 1 1 0 2 2 2 0 Prolyl oligopeptidase family Yip1 PF04893.12 ETO20622.1 - 2.4 7.6 14.7 0.16 11.4 1.4 3.0 2 1 1 3 3 3 0 Yip1 domain IF2_assoc PF08364.6 ETO20623.1 - 0.14 12.1 7.0 0.15 12.1 3.7 2.0 2 1 0 2 2 2 0 Bacterial translation initiation factor IF-2 associated region DUF2992 PF11208.3 ETO20623.1 - 5 7.0 16.6 8.2 6.3 11.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Sec3-PIP2_bind PF15277.1 ETO20624.1 - 0.0033 17.2 0.9 6.3 6.7 0.1 3.4 3 0 0 3 3 3 2 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps39_2 PF10367.4 ETO20625.1 - 4.5e-15 55.7 0.8 1.1e-11 44.8 0.0 3.6 3 0 0 3 3 3 2 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.15 ETO20625.1 - 1.9e-05 24.3 9.9 0.0001 21.9 1.5 4.2 2 2 0 2 2 2 1 Region in Clathrin and VPS Vps39_1 PF10366.4 ETO20625.1 - 5.3e-05 23.1 5.8 0.0073 16.3 0.1 4.0 2 1 0 3 3 3 2 Vacuolar sorting protein 39 domain 1 CAP_C PF08603.6 ETO20626.1 - 9.4e-18 64.0 11.8 1.9e-15 56.5 5.3 2.5 2 1 0 2 2 2 2 Adenylate cyclase associated (CAP) C terminal Wzy_C PF04932.10 ETO20626.1 - 0.00026 20.8 0.7 0.00036 20.3 0.5 1.1 1 0 0 1 1 1 1 O-Antigen ligase DUF3855 PF12967.2 ETO20626.1 - 0.014 14.9 0.4 0.026 14.0 0.2 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3855) WBP-1 PF11669.3 ETO20626.1 - 0.037 14.1 0.5 0.051 13.6 0.3 1.3 1 0 0 1 1 1 0 WW domain-binding protein 1 DUF3923 PF13061.1 ETO20626.1 - 1.8 8.4 6.5 5.1 7.0 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3923) PT PF04886.7 ETO20627.1 - 0.00047 19.4 24.9 0.00047 19.4 17.2 6.8 3 3 2 5 5 5 1 PT repeat DUF445 PF04286.7 ETO20627.1 - 4.6 6.6 20.3 6.7 6.1 14.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) GP40 PF11025.3 ETO20628.1 - 0.057 12.9 0.1 0.093 12.3 0.1 1.3 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium CobT PF06213.7 ETO20629.1 - 0.018 14.1 23.9 0.024 13.7 16.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SGT1 PF07093.6 ETO20629.1 - 0.84 7.9 17.6 0.97 7.7 12.2 1.3 1 0 0 1 1 1 0 SGT1 protein Glypican PF01153.14 ETO20629.1 - 8.7 4.8 8.6 9.8 4.6 6.0 1.2 1 0 0 1 1 1 0 Glypican BDHCT PF08072.6 ETO20630.1 - 0.026 14.6 0.3 0.061 13.4 0.0 1.7 2 0 0 2 2 2 0 BDHCT (NUC031) domain Eco57I PF07669.6 ETO20630.1 - 0.065 13.5 0.1 0.083 13.2 0.1 1.3 1 0 0 1 1 1 0 Eco57I restriction-modification methylase TetR_C_8 PF14278.1 ETO20630.1 - 0.076 13.3 2.9 0.88 9.9 0.1 2.2 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region Reo_sigmaC PF04582.7 ETO20632.1 - 0.041 13.0 1.1 0.069 12.3 0.8 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Phage_GP20 PF06810.6 ETO20632.1 - 0.22 10.9 36.0 0.044 13.2 20.6 2.9 1 1 1 2 2 2 0 Phage minor structural protein GP20 OsmC PF02566.14 ETO20632.1 - 0.64 10.2 3.3 2.6 8.2 0.6 2.7 2 0 0 2 2 2 0 OsmC-like protein YjgP_YjgQ PF03739.9 ETO20632.1 - 1.6 7.3 8.7 2.3 6.8 6.0 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family IncA PF04156.9 ETO20632.1 - 5.3 6.5 30.6 14 5.2 21.0 1.9 1 1 0 1 1 1 0 IncA protein USP8_interact PF08941.5 ETO20632.1 - 9.3 5.5 13.9 0.17 11.1 3.4 2.1 1 1 1 2 2 2 0 USP8 interacting Reo_sigmaC PF04582.7 ETO20633.1 - 0.04 13.0 3.2 0.038 13.1 0.9 1.5 1 1 0 1 1 1 0 Reovirus sigma C capsid protein zf-C3HC4_2 PF13923.1 ETO20633.1 - 0.11 12.5 4.8 0.73 9.9 3.3 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Vma12 PF11712.3 ETO20633.1 - 1.3 8.7 9.1 4.2 7.0 6.3 1.8 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Mitofilin PF09731.4 ETO20633.1 - 2.2 6.8 28.1 2.5 6.6 19.5 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein GvpK PF05121.7 ETO20633.1 - 6.2 6.7 12.2 4.8 7.0 2.4 3.6 1 1 2 3 3 3 0 Gas vesicle protein K Ras PF00071.17 ETO20634.1 - 6.2e-22 77.7 0.1 9.7e-22 77.0 0.1 1.2 1 0 0 1 1 1 1 Ras family Arf PF00025.16 ETO20634.1 - 1.4e-06 27.7 0.1 2.1e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 ETO20634.1 - 3.4e-05 24.3 0.0 8.1e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 ETO20634.1 - 0.00025 20.5 0.3 0.00048 19.6 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 ETO20634.1 - 0.012 14.7 0.1 0.02 14.0 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF367 PF04034.8 ETO20635.1 - 3.5e-34 117.1 0.0 5.7e-34 116.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 ETO20635.1 - 2.4e-12 46.2 0.1 4.5e-12 45.3 0.1 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Ras PF00071.17 ETO20636.1 - 2e-06 27.2 0.0 4.2e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 Ras family DUF4583 PF15190.1 ETO20637.1 - 0.11 12.1 0.8 0.22 11.1 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4583) DUF1183 PF06682.7 ETO20637.1 - 4.4 6.8 7.4 11 5.4 4.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1183) Tropomyosin_1 PF12718.2 ETO20638.1 - 0.0034 17.2 6.0 0.0034 17.2 4.2 2.9 2 1 0 2 2 2 1 Tropomyosin like Lzipper-MIP1 PF14389.1 ETO20638.1 - 0.021 14.9 1.9 0.021 14.9 1.3 2.6 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Rabaptin PF03528.10 ETO20638.1 - 0.044 13.7 18.1 0.15 12.0 4.0 3.1 2 1 1 3 3 3 0 Rabaptin DUF4613 PF15390.1 ETO20638.1 - 2.1 6.4 7.5 2.6 6.1 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) APG6 PF04111.7 ETO20638.1 - 4 6.4 14.1 2.3 7.2 7.6 1.8 2 0 0 2 2 2 0 Autophagy protein Apg6 Fib_alpha PF08702.5 ETO20638.1 - 5.1 7.2 11.7 0.65 10.1 4.6 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.4 ETO20638.1 - 7.9 6.3 19.2 0.61 9.9 8.5 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sec2p PF06428.6 ETO20638.1 - 8.9 6.2 15.8 0.074 12.9 1.6 3.0 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p V_ATPase_I PF01496.14 ETO20640.1 - 0.032 12.0 0.6 0.04 11.7 0.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.3 ETO20640.1 - 0.039 13.7 1.3 0.039 13.7 0.9 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 ETO20640.1 - 0.091 12.3 5.3 0.071 12.6 2.8 1.5 1 1 1 2 2 2 0 IncA protein Dynein_light PF01221.13 ETO20642.1 - 2.8e-20 72.1 1.2 2.8e-20 72.1 0.8 2.0 1 1 1 2 2 2 1 Dynein light chain type 1 RRP7 PF12923.2 ETO20642.1 - 0.0056 16.7 3.2 0.0076 16.2 2.2 1.1 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) BicD PF09730.4 ETO20642.1 - 0.043 12.1 0.1 0.048 12.0 0.0 1.0 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Cytochrom_B561 PF03188.11 ETO20642.1 - 0.12 12.1 2.2 0.23 11.2 0.3 2.0 1 1 0 2 2 2 0 Eukaryotic cytochrome b561 DUF740 PF05340.7 ETO20642.1 - 1.5 7.0 4.4 1.6 6.9 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) DUF1510 PF07423.6 ETO20643.1 - 0.00017 21.0 14.2 0.00043 19.7 9.9 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1510) CDC45 PF02724.9 ETO20643.1 - 0.00035 18.7 12.2 0.00044 18.4 8.5 1.1 1 0 0 1 1 1 1 CDC45-like protein Neur_chan_memb PF02932.11 ETO20643.1 - 0.0009 19.1 3.6 0.0011 18.8 2.5 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2457 PF10446.4 ETO20643.1 - 0.0017 17.2 26.1 0.0017 17.2 18.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2457) SpoIIIAH PF12685.2 ETO20643.1 - 0.007 15.8 4.1 0.011 15.2 2.8 1.3 1 1 0 1 1 1 1 SpoIIIAH-like protein AAA-ATPase_like PF09820.4 ETO20643.1 - 0.01 15.0 1.0 0.014 14.5 0.7 1.2 1 0 0 1 1 1 0 Predicted AAA-ATPase Ycf1 PF05758.7 ETO20643.1 - 0.013 13.3 5.6 0.014 13.1 3.9 1.1 1 0 0 1 1 1 0 Ycf1 SID-1_RNA_chan PF13965.1 ETO20643.1 - 0.013 13.6 5.4 0.0064 14.7 2.3 1.5 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 Mem_trans PF03547.13 ETO20643.1 - 0.025 12.8 1.4 0.031 12.6 0.9 1.2 1 0 0 1 1 1 0 Membrane transport protein Nop14 PF04147.7 ETO20643.1 - 0.026 12.4 15.6 0.033 12.1 10.8 1.1 1 0 0 1 1 1 0 Nop14-like family Herpes_gE PF02480.11 ETO20643.1 - 0.028 12.6 0.6 0.036 12.3 0.3 1.3 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E BUD22 PF09073.5 ETO20643.1 - 0.03 13.3 15.2 0.037 13.0 10.5 1.1 1 0 0 1 1 1 0 BUD22 DUF1183 PF06682.7 ETO20643.1 - 0.031 13.8 0.0 0.039 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) TRAP_alpha PF03896.11 ETO20643.1 - 0.032 13.2 9.2 0.032 13.2 5.8 1.3 1 1 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Daxx PF03344.10 ETO20643.1 - 0.059 11.8 13.2 0.07 11.6 9.2 1.1 1 0 0 1 1 1 0 Daxx Family DUF929 PF06053.6 ETO20643.1 - 0.099 11.7 0.2 0.16 10.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF929) Cytochrome-c551 PF10643.4 ETO20643.1 - 0.1 11.8 2.0 0.24 10.6 1.4 1.6 1 1 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 MAPEG PF01124.13 ETO20643.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 MAPEG family Tetraspannin PF00335.15 ETO20643.1 - 0.16 11.1 0.9 0.24 10.6 0.6 1.5 1 1 0 1 1 1 0 Tetraspanin family GP41 PF00517.12 ETO20643.1 - 0.34 10.4 3.3 0.76 9.3 2.3 1.5 1 0 0 1 1 1 0 Retroviral envelope protein Tmemb_9 PF05434.6 ETO20643.1 - 0.42 10.3 15.2 0.052 13.3 3.8 2.4 1 1 1 2 2 2 0 TMEM9 FAM176 PF14851.1 ETO20643.1 - 0.43 10.2 11.6 3.4 7.3 7.3 2.5 1 1 1 2 2 2 0 FAM176 family YL1 PF05764.8 ETO20643.1 - 0.58 9.7 16.7 0.86 9.1 11.6 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Astro_capsid PF03115.9 ETO20643.1 - 0.6 8.2 8.0 0.7 8.0 5.6 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor RRN3 PF05327.6 ETO20643.1 - 0.69 7.9 12.8 0.86 7.6 8.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4446 PF14584.1 ETO20643.1 - 1 9.2 11.2 0.57 9.9 2.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Zip PF02535.17 ETO20643.1 - 1.3 7.9 8.9 3.5 6.5 6.2 1.7 1 1 0 1 1 1 0 ZIP Zinc transporter Hid1 PF12722.2 ETO20643.1 - 1.6 6.2 7.1 1.9 6.0 4.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sigma_reg_N PF13800.1 ETO20643.1 - 1.8 8.6 11.7 1.3 9.0 6.8 1.7 2 0 0 2 2 1 0 Sigma factor regulator N-terminal Folate_carrier PF01770.13 ETO20643.1 - 2.5 6.5 5.4 0.59 8.5 0.1 1.9 1 1 1 2 2 2 0 Reduced folate carrier Sporozoite_P67 PF05642.6 ETO20643.1 - 2.5 5.8 6.3 3.2 5.5 4.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DAG1 PF05454.6 ETO20643.1 - 2.7 7.0 5.1 5 6.2 3.6 1.4 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Vpu PF00558.14 ETO20643.1 - 4 7.0 6.8 0.44 10.1 1.6 1.8 2 1 0 2 2 1 0 Vpu protein SGT1 PF07093.6 ETO20643.1 - 7.8 4.7 19.2 10 4.3 13.3 1.2 1 0 0 1 1 1 0 SGT1 protein FAM163 PF15069.1 ETO20643.1 - 8.7 6.9 7.2 24 5.5 0.5 2.2 2 0 0 2 2 2 0 FAM163 family RNase_PH PF01138.16 ETO20644.1 - 2.8e-08 34.1 0.1 9.1e-07 29.2 0.0 2.7 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 ETO20644.1 - 0.039 13.8 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 RTC PF01137.16 ETO20645.1 - 6.7e-36 123.1 0.0 2.2e-17 62.6 0.0 2.1 2 0 0 2 2 2 2 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 ETO20645.1 - 4.4e-14 52.3 0.0 1.6e-11 44.0 0.1 2.3 2 0 0 2 2 2 2 RNA 3'-terminal phosphate cyclase (RTC), insert domain DUF3753 PF12575.3 ETO20645.1 - 0.25 11.1 4.0 3.1 7.6 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) WD40 PF00400.27 ETO20646.1 - 2e-90 293.7 13.4 5.5e-13 48.2 0.1 7.0 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO20646.1 - 5.3e-11 42.5 0.2 9e-06 25.5 0.0 3.3 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO20646.1 - 7.1e-11 40.9 8.6 0.16 10.0 0.1 6.5 1 1 5 7 7 7 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO20646.1 - 4.4e-08 31.8 2.0 0.002 16.4 0.1 3.0 1 1 2 3 3 3 2 Cytochrome D1 heme domain BBS2_Mid PF14783.1 ETO20646.1 - 3.2e-07 30.1 2.6 0.7 9.6 0.1 5.3 2 1 2 4 4 4 2 Ciliary BBSome complex subunit 2, middle region PD40 PF07676.7 ETO20646.1 - 1.4e-06 27.8 6.5 5.9 6.6 0.0 6.1 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.9 ETO20646.1 - 1.5e-05 24.0 1.0 0.097 11.4 0.4 3.0 1 1 2 3 3 3 2 Coatomer WD associated region Nbas_N PF15492.1 ETO20646.1 - 1.7e-05 24.0 1.3 0.56 9.2 0.0 4.7 2 1 3 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 ETO20646.1 - 3.2e-05 22.8 12.2 0.0046 15.7 1.5 4.9 1 1 3 4 4 4 1 Nup133 N terminal like DPPIV_N PF00930.16 ETO20646.1 - 0.003 16.2 0.8 0.68 8.4 0.1 3.5 2 2 2 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region SGL PF08450.7 ETO20646.1 - 0.0031 16.9 0.9 2.6 7.3 0.0 2.9 1 1 2 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region DUF4072 PF13284.1 ETO20646.1 - 0.0038 17.3 0.0 17 5.6 0.0 4.7 6 0 0 6 6 6 0 Domain of unknown function (DUF4072) DUF1652 PF07865.6 ETO20646.1 - 0.011 15.3 0.0 14 5.3 0.0 3.7 5 0 0 5 5 5 0 Protein of unknown function (DUF1652) Gmad1 PF10647.4 ETO20646.1 - 0.019 14.3 0.0 0.57 9.5 0.0 2.7 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain HARP PF07443.8 ETO20646.1 - 0.15 11.4 0.5 1.5 8.2 0.0 2.9 4 0 0 4 4 4 0 HepA-related protein (HARP) UN_NPL4 PF11543.3 ETO20646.1 - 0.15 12.3 0.6 50 4.2 0.0 4.2 4 1 0 4 4 3 0 Nuclear pore localisation protein NPL4 Proteasome_A_N PF10584.4 ETO20646.1 - 8.3 5.8 11.6 18 4.7 0.0 5.1 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature Kelch_1 PF01344.20 ETO20647.1 - 8.6e-08 31.6 6.4 0.013 15.0 0.3 4.8 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO20647.1 - 1.2e-06 28.3 4.2 0.03 14.5 0.1 3.9 3 1 1 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO20647.1 - 0.0045 16.7 2.3 4.1 7.2 0.0 4.2 3 1 1 4 4 4 2 Galactose oxidase, central domain NAD_binding_1 PF00175.16 ETO20647.1 - 0.0098 16.4 0.2 0.11 13.0 0.0 2.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DNA_pol3_beta_2 PF02767.11 ETO20647.1 - 0.095 12.7 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 DNA polymerase III beta subunit, central domain Kelch_5 PF13854.1 ETO20647.1 - 0.1 12.5 6.6 7.8 6.5 0.0 3.8 3 0 0 3 3 3 0 Kelch motif WD40 PF00400.27 ETO20648.1 - 6.2e-68 222.4 25.1 1.4e-13 50.1 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO20648.1 - 4.3e-08 31.7 5.1 0.012 13.7 0.0 4.1 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 ETO20648.1 - 1.7e-07 30.4 1.6 0.00015 20.6 0.1 2.4 1 1 1 2 2 2 2 Coatomer WD associated region PD40 PF07676.7 ETO20648.1 - 3.2e-07 29.8 10.8 3.9 7.2 0.1 6.2 6 0 0 6 6 6 4 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO20648.1 - 5.5e-06 26.0 0.7 0.034 13.6 0.1 2.9 1 1 2 3 3 3 2 PQQ-like domain DPPIV_N PF00930.16 ETO20648.1 - 1.8e-05 23.4 0.1 0.037 12.6 0.0 3.7 1 1 3 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Cytochrom_D1 PF02239.11 ETO20648.1 - 2.6e-05 22.7 0.5 0.076 11.3 0.0 2.8 1 1 2 3 3 3 2 Cytochrome D1 heme domain Resistin PF06954.6 ETO20648.1 - 0.00044 20.4 3.5 26 5.1 0.0 5.5 1 1 4 6 6 6 0 Resistin Nbas_N PF15492.1 ETO20648.1 - 0.00046 19.3 5.1 0.16 11.0 0.0 4.3 1 1 3 5 5 5 1 Neuroblastoma-amplified sequence, N terminal VID27 PF08553.5 ETO20648.1 - 0.0012 17.1 0.0 0.0035 15.6 0.0 1.6 1 1 1 2 2 2 1 VID27 cytoplasmic protein Lactonase PF10282.4 ETO20648.1 - 0.0021 17.1 0.1 0.01 14.9 0.0 2.1 2 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller NTNH_C PF08470.5 ETO20648.1 - 0.011 15.4 1.2 3.1 7.4 0.0 2.7 1 1 2 3 3 3 0 Nontoxic nonhaemagglutinin C-terminal DUF2415 PF10313.4 ETO20648.1 - 0.013 15.1 0.1 8.9 6.0 0.0 4.2 4 0 0 4 4 4 0 Uncharacterised protein domain (DUF2415) NHL PF01436.16 ETO20648.1 - 0.077 12.9 0.0 3.5 7.7 0.0 3.3 3 0 0 3 3 3 0 NHL repeat Ricin_B_lectin PF00652.17 ETO20648.1 - 0.16 11.9 1.7 17 5.4 0.1 3.3 1 1 1 3 3 3 0 Ricin-type beta-trefoil lectin domain Proteasome_A_N PF10584.4 ETO20648.1 - 3 7.2 12.0 16 4.9 0.0 5.1 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature Exostosin PF03016.10 ETO20650.1 - 9.7e-23 80.6 0.0 1.2e-21 77.0 0.0 2.4 1 1 0 1 1 1 1 Exostosin family tRNA-synt_His PF13393.1 ETO20651.1 - 2.5e-23 82.6 0.1 4.9e-23 81.6 0.1 1.4 1 1 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.15 ETO20651.1 - 0.00032 20.5 0.0 0.00071 19.4 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.20 ETO20651.1 - 0.019 14.5 0.1 0.041 13.4 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) DUF4291 PF14124.1 ETO20652.1 - 2.7e-05 23.8 1.3 3.3e-05 23.5 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) SCO1-SenC PF02630.9 ETO20652.1 - 0.0085 15.7 0.1 0.013 15.1 0.1 1.3 1 0 0 1 1 1 1 SCO1/SenC V-ATPase_H_C PF11698.3 ETO20652.1 - 0.0091 15.9 1.1 0.013 15.3 0.8 1.5 1 1 0 1 1 1 1 V-ATPase subunit H gp45-slide_C PF09116.5 ETO20652.1 - 0.077 12.9 0.2 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 gp45 sliding clamp, C terminal DUF162 PF02589.10 ETO20652.1 - 0.12 11.8 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised ACR, YkgG family COG1556 Troponin PF00992.15 ETO20652.1 - 0.17 11.9 3.5 2.6 8.1 2.4 2.1 1 1 0 1 1 1 0 Troponin DUF2951 PF11166.3 ETO20653.1 - 7.1 6.5 10.5 1.3 8.8 0.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2951) DUF553 PF04473.7 ETO20654.1 - 0.0012 18.1 0.6 0.0019 17.5 0.4 1.2 1 0 0 1 1 1 1 Transglutaminase-like domain DUF2513 PF10711.4 ETO20654.1 - 0.019 15.0 0.0 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) TaqI_C PF12950.2 ETO20654.1 - 0.046 13.4 0.6 0.099 12.3 0.4 1.5 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain Trns_repr_metal PF02583.12 ETO20654.1 - 0.062 13.4 0.1 0.14 12.3 0.1 1.6 1 0 0 1 1 1 0 Metal-sensitive transcriptional repressor Ribosomal_S13_N PF08069.7 ETO20654.1 - 0.42 10.4 2.7 0.94 9.3 1.9 1.6 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain DUF2164 PF09932.4 ETO20654.1 - 0.72 9.7 4.1 23 4.8 1.0 3.3 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2164) DUF3135 PF11333.3 ETO20655.1 - 6.1e-05 23.1 11.0 0.077 13.1 1.4 4.2 3 1 1 4 4 4 3 Protein of unknown function (DUF3135) DUF740 PF05340.7 ETO20656.1 - 0.68 8.2 14.7 0.8 7.9 10.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF740) VIT1 PF01988.14 ETO20656.1 - 2.8 7.3 5.0 3.1 7.2 3.5 1.0 1 0 0 1 1 1 0 VIT family TRAP_alpha PF03896.11 ETO20656.1 - 5 6.0 10.2 5.3 5.9 7.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.7 ETO20656.1 - 5.1 4.8 16.7 5.3 4.8 11.6 1.0 1 0 0 1 1 1 0 Nop14-like family OMP_b-brl_2 PF13568.1 ETO20657.1 - 1.8 8.3 4.8 28 4.4 3.3 2.6 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain RFC1 PF08519.7 ETO20659.1 - 0.012 15.3 0.4 0.015 15.0 0.3 1.1 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain Ank_2 PF12796.2 ETO20660.1 - 2.5e-06 27.7 0.2 0.007 16.6 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO20660.1 - 0.0014 19.1 0.6 1.2 9.7 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) CobT PF06213.7 ETO20660.1 - 0.013 14.6 4.1 0.022 13.8 2.9 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ank PF00023.25 ETO20660.1 - 0.042 13.6 2.0 42 4.2 0.0 4.2 4 0 0 4 4 4 0 Ankyrin repeat Ank_5 PF13857.1 ETO20660.1 - 0.049 13.9 0.2 1.6 9.0 0.0 3.1 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Rib_recp_KP_reg PF05104.7 ETO20660.1 - 2.2 8.7 10.5 4 7.9 7.3 1.4 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region DUF4079 PF13301.1 ETO20661.1 - 0.13 12.2 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) SNase PF00565.12 ETO20662.1 - 9.8e-10 38.6 6.3 6e-08 32.9 0.1 2.7 3 0 0 3 3 3 2 Staphylococcal nuclease homologue Herpes_LMP1 PF05297.6 ETO20662.1 - 0.74 8.6 8.9 1.1 8.1 6.2 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF936 PF06075.7 ETO20663.1 - 8.9 5.1 30.1 12 4.6 20.8 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) PP2C PF00481.16 ETO20664.1 - 1.1e-35 123.2 2.7 3.1e-35 121.7 1.9 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C Macoilin PF09726.4 ETO20664.1 - 0.0023 16.3 4.4 0.002 16.4 3.1 1.1 1 0 0 1 1 1 1 Transmembrane protein SpoIIE PF07228.7 ETO20664.1 - 0.0044 16.7 0.0 0.0094 15.6 0.0 1.5 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) CAP_GLY PF01302.20 ETO20668.1 - 7.1e-15 54.4 0.0 1.2e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain DUF4512 PF14975.1 ETO20668.1 - 1.8 9.4 9.8 0.2 12.4 0.6 3.3 2 2 0 2 2 2 0 Domain of unknown function (DUF4512) DUF912 PF06024.7 ETO20668.1 - 1.8 8.6 10.3 42 4.2 0.0 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Serinc PF03348.10 ETO20668.1 - 2.6 6.6 5.3 3.9 6.0 3.7 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Adeno_52K PF03052.10 ETO20669.1 - 0.02 14.1 0.7 0.02 14.1 0.5 2.0 1 1 1 2 2 2 0 Adenoviral protein L1 52/55-kDa FAM178 PF14816.1 ETO20669.1 - 1.1 7.9 6.4 0.71 8.5 3.5 1.4 1 1 0 1 1 1 0 Family of unknown function, FAM178 Hypoth_Ymh PF09509.5 ETO20669.1 - 2.6 7.7 7.2 3.6 7.2 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (Hypoth_ymh) Macoilin PF09726.4 ETO20669.1 - 4.3 5.5 20.6 4.6 5.4 14.3 1.0 1 0 0 1 1 1 0 Transmembrane protein Sec7_N PF12783.2 ETO20671.1 - 3.9e-11 42.6 0.5 7e-11 41.8 0.1 1.5 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal SAM_2 PF07647.12 ETO20673.1 - 1.7e-11 43.7 0.5 3e-11 42.9 0.4 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO20673.1 - 2.5e-11 43.5 0.6 4.4e-11 42.7 0.4 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) KSR1-SAM PF13543.1 ETO20673.1 - 0.58 9.9 5.2 0.098 12.4 0.9 1.7 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 Zip PF02535.17 ETO20673.1 - 0.63 9.0 3.1 0.73 8.7 2.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 ETO20673.1 - 0.81 9.0 13.5 2.1 7.6 9.4 1.6 1 1 0 1 1 1 0 Selenoprotein P, N terminal region WD40 PF00400.27 ETO20674.1 - 0.057 13.3 0.8 0.17 11.8 0.6 1.9 1 0 0 1 1 1 0 WD domain, G-beta repeat DUF2207 PF09972.4 ETO20675.1 - 0.29 9.6 6.4 0.33 9.5 4.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RabGAP-TBC PF00566.13 ETO20678.1 - 2.8e-21 76.0 6.5 2.8e-18 66.1 1.6 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain G-alpha PF00503.15 ETO20679.1 - 4.5e-19 68.4 2.8 5e-19 68.2 1.9 1.1 1 0 0 1 1 1 1 G-protein alpha subunit DUF815 PF05673.8 ETO20679.1 - 0.0013 17.6 0.0 0.0017 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Miro PF08477.8 ETO20679.1 - 0.0036 17.7 0.1 0.0084 16.6 0.0 1.6 1 1 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 ETO20679.1 - 0.005 17.1 1.1 0.0079 16.4 0.2 1.7 1 1 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.13 ETO20679.1 - 0.005 16.3 0.0 0.0093 15.4 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_29 PF13555.1 ETO20679.1 - 0.0078 15.7 0.0 0.017 14.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.1 ETO20679.1 - 0.0091 15.8 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 ETO20679.1 - 0.0097 15.8 0.1 0.018 15.0 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 ETO20679.1 - 0.013 15.4 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.17 ETO20679.1 - 0.015 14.1 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.1 ETO20679.1 - 0.018 14.9 0.4 0.024 14.5 0.0 1.5 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 ETO20679.1 - 0.021 14.5 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 ETO20679.1 - 0.041 13.3 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Lipoprotein_Ltp PF07553.6 ETO20679.1 - 0.041 13.7 0.1 0.11 12.4 0.1 1.8 1 0 0 1 1 1 0 Host cell surface-exposed lipoprotein AAA_5 PF07728.9 ETO20679.1 - 0.054 13.2 0.2 0.13 11.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 ETO20679.1 - 0.067 14.0 0.1 0.11 13.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 ETO20679.1 - 0.094 12.8 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 ETO20679.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.7 ETO20679.1 - 0.3 10.3 1.4 0.51 9.5 0.2 1.9 1 1 0 1 1 1 0 Poxvirus A32 protein Guanylate_kin PF00625.16 ETO20679.1 - 0.37 10.2 2.9 0.9 8.9 0.3 2.5 1 1 1 2 2 2 0 Guanylate kinase Xpo1 PF08389.7 ETO20680.1 - 1.9e-08 34.3 0.4 6.5e-08 32.6 0.2 1.8 2 0 0 2 2 2 1 Exportin 1-like protein YWFCY PF14293.1 ETO20681.1 - 0.067 13.0 0.8 20 5.1 0.0 3.2 3 0 0 3 3 3 0 YWFCY protein PRP1_N PF06424.7 ETO20681.1 - 0.15 12.3 0.6 0.34 11.2 0.4 1.5 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Ras PF00071.17 ETO20682.1 - 4e-38 130.3 0.0 1.1e-36 125.6 0.0 2.4 1 1 0 1 1 1 1 Ras family Miro PF08477.8 ETO20682.1 - 3.2e-14 53.4 0.1 1.1e-13 51.7 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO20682.1 - 0.00038 19.7 0.3 0.0013 18.0 0.0 2.0 2 1 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETO20682.1 - 0.0039 17.1 0.0 0.0084 16.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 ETO20682.1 - 0.051 13.0 1.4 1.7 8.0 0.0 3.0 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF3184 PF11380.3 ETO20683.1 - 0.033 12.1 0.0 0.038 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3184) PH PF00169.24 ETO20684.1 - 0.0086 16.2 0.8 0.34 11.1 0.0 2.7 2 0 0 2 2 2 2 PH domain Myb_DNA-bind_5 PF13873.1 ETO20685.1 - 0.016 15.1 5.4 3.4 7.6 0.1 3.6 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain DUF3199 PF11436.3 ETO20685.1 - 0.055 13.3 0.2 13 5.6 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3199) Ku PF02735.11 ETO20687.1 - 4.9e-34 117.5 0.7 1.5e-33 115.9 0.0 1.9 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_C PF03730.9 ETO20687.1 - 1.4e-10 41.5 3.8 3.7e-10 40.2 0.6 2.6 1 1 0 2 2 2 1 Ku70/Ku80 C-terminal arm Ku_PK_bind PF08785.6 ETO20688.1 - 3.7e-13 49.4 1.3 4.9e-13 49.0 0.9 1.1 1 0 0 1 1 1 1 Ku C terminal domain like Clat_adaptor_s PF01217.15 ETO20693.1 - 1.7e-46 157.4 11.1 9.3e-34 116.1 3.6 2.1 1 1 1 2 2 2 2 Clathrin adaptor complex small chain DUF3611 PF12263.3 ETO20693.1 - 0.081 12.3 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) zf-NPL4 PF05020.10 ETO20693.1 - 0.11 12.2 0.1 0.27 10.8 0.1 1.6 1 1 0 1 1 1 0 NPL4 family, putative zinc binding region Picorna_P3A PF06363.6 ETO20693.1 - 0.49 10.4 3.5 0.24 11.4 0.3 2.0 2 1 1 3 3 3 0 Picornaviridae P3A protein Ndc1_Nup PF09531.5 ETO20694.1 - 1.7 6.9 11.0 2.9 6.2 7.6 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TrbL PF04610.9 ETO20695.1 - 0.37 10.4 1.9 0.33 10.6 0.2 1.8 1 1 1 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein PspB PF06667.7 ETO20696.1 - 0.0059 16.5 1.3 0.0059 16.5 0.9 2.3 2 0 0 2 2 2 1 Phage shock protein B GAS PF13851.1 ETO20696.1 - 0.89 8.7 14.2 0.059 12.5 5.6 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 ETO20696.1 - 3.3 7.2 22.3 0.17 11.4 7.5 2.4 3 0 0 3 3 3 0 IncA protein DASH_Dad2 PF08654.5 ETO20696.1 - 5 7.1 6.8 0.96 9.4 0.9 2.5 3 0 0 3 3 3 0 DASH complex subunit Dad2 Phasin PF05597.6 ETO20696.1 - 6.5 6.5 7.8 4 7.1 0.7 2.7 3 1 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) SAM_2 PF07647.12 ETO20697.1 - 3.4e-13 49.2 4.2 1e-06 28.4 0.1 2.8 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO20697.1 - 5.6e-08 32.8 5.9 0.0058 16.7 0.1 3.3 3 0 0 3 3 3 2 SAM domain (Sterile alpha motif) DUF2683 PF10884.3 ETO20697.1 - 0.052 13.4 2.7 0.15 11.9 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF2683) SRP14 PF02290.10 ETO20697.1 - 0.33 10.8 4.9 0.15 11.9 1.2 2.2 2 0 0 2 2 2 0 Signal recognition particle 14kD protein CPSF100_C PF13299.1 ETO20697.1 - 0.51 10.5 3.9 1.2 9.3 2.7 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Spc7 PF08317.6 ETO20698.1 - 0.0009 17.9 3.0 0.0009 17.9 2.1 2.1 1 1 1 2 2 2 1 Spc7 kinetochore protein BLOC1_2 PF10046.4 ETO20698.1 - 0.0014 18.7 4.0 0.79 9.9 0.1 2.8 2 0 0 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prefoldin_2 PF01920.15 ETO20698.1 - 0.018 14.7 13.5 0.23 11.2 2.4 2.8 2 1 0 2 2 2 0 Prefoldin subunit SIC PF03482.8 ETO20698.1 - 0.032 13.8 0.0 0.046 13.3 0.0 1.1 1 0 0 1 1 1 0 sic protein Baculo_PEP_C PF04513.7 ETO20698.1 - 0.054 13.3 2.9 3 7.6 0.2 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phytoreo_Pns PF05451.6 ETO20698.1 - 0.076 11.6 0.2 0.17 10.5 0.1 1.5 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns10/11 NPV_P10 PF05531.7 ETO20698.1 - 0.091 13.0 4.9 0.65 10.2 0.1 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein HR1 PF02185.11 ETO20698.1 - 0.12 12.1 6.9 0.15 11.7 1.3 3.1 3 0 0 3 3 3 0 Hr1 repeat Osmo_CC PF08946.5 ETO20698.1 - 0.14 12.1 0.4 0.14 12.1 0.3 2.4 2 0 0 2 2 2 0 Osmosensory transporter coiled coil COG2 PF06148.6 ETO20698.1 - 0.28 11.0 8.3 2.8 7.8 0.5 2.9 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CENP-F_leu_zip PF10473.4 ETO20698.1 - 0.44 10.4 11.2 2.2 8.1 0.3 2.6 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 V_ATPase_I PF01496.14 ETO20698.1 - 0.65 7.7 11.2 5.3 4.7 7.8 1.9 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 ETO20698.1 - 0.88 9.1 19.5 0.43 10.1 2.7 2.2 1 1 1 2 2 2 0 IncA protein Filament PF00038.16 ETO20698.1 - 1.1 8.6 19.8 5.1 6.4 4.9 2.5 1 1 1 2 2 2 0 Intermediate filament protein DUF848 PF05852.6 ETO20698.1 - 1.7 8.5 12.7 0.4 10.5 3.0 2.6 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF310 PF03750.8 ETO20698.1 - 1.7 8.8 5.0 0.97 9.6 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF310) DUF948 PF06103.6 ETO20698.1 - 2.9 7.7 5.5 1.5 8.7 0.3 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DivIC PF04977.10 ETO20698.1 - 4.9 6.7 7.2 5.8 6.4 1.7 2.6 2 0 0 2 2 2 0 Septum formation initiator DUF4200 PF13863.1 ETO20698.1 - 5 7.0 16.1 2.6 7.9 1.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) IFT57 PF10498.4 ETO20698.1 - 5.1 5.7 16.7 1.7 7.2 6.1 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Occludin_ELL PF07303.8 ETO20698.1 - 6.7 7.5 11.9 0.73 10.5 1.7 3.1 1 1 2 3 3 3 0 Occludin homology domain Cortex-I_coil PF09304.5 ETO20698.1 - 9.1 6.3 12.7 10 6.2 2.3 3.2 2 1 1 3 3 3 0 Cortexillin I, coiled coil Myc_N PF01056.13 ETO20699.1 - 0.2 10.8 2.0 0.14 11.3 0.2 1.6 2 0 0 2 2 2 0 Myc amino-terminal region SprT-like PF10263.4 ETO20700.1 - 0.007 16.0 5.5 0.0075 15.9 2.5 2.1 2 0 0 2 2 2 1 SprT-like family zf-TRAF PF02176.13 ETO20701.1 - 2.8e-07 30.7 2.0 2.8e-07 30.7 1.4 3.6 3 1 0 3 3 3 1 TRAF-type zinc finger DUF4618 PF15397.1 ETO20701.1 - 0.62 9.3 11.5 0.029 13.7 2.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DivIC PF04977.10 ETO20701.1 - 0.88 9.0 7.9 0.99 8.9 0.7 2.4 2 0 0 2 2 2 0 Septum formation initiator zf-C3HC4_2 PF13923.1 ETO20701.1 - 1.9 8.6 9.1 3.6 7.6 0.0 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Kelch_4 PF13418.1 ETO20702.1 - 2e-39 133.0 11.9 9.4e-10 38.1 0.0 6.6 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO20702.1 - 4.3e-32 109.5 1.8 1.1e-07 31.5 0.0 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_3 PF13415.1 ETO20702.1 - 8e-32 108.6 21.5 2.1e-10 40.4 0.0 7.7 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO20702.1 - 4.9e-29 98.9 6.1 1.1e-09 37.6 0.0 5.9 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.1 ETO20702.1 - 9.2e-26 88.9 4.8 7e-07 29.1 0.0 5.8 3 1 2 5 5 5 5 Kelch motif Kelch_1 PF01344.20 ETO20702.1 - 4.1e-25 87.0 6.8 1.4e-06 27.7 0.0 6.3 5 1 1 6 6 6 4 Kelch motif Apolipoprotein PF01442.13 ETO20702.1 - 0.0017 17.9 2.6 0.0027 17.2 1.8 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain RAG2 PF03089.9 ETO20702.1 - 0.011 14.4 0.9 1.1 7.8 0.0 3.3 4 0 0 4 4 4 0 Recombination activating protein 2 Macoilin PF09726.4 ETO20702.1 - 6.4 4.9 27.0 0.73 8.0 11.1 2.2 2 0 0 2 2 2 0 Transmembrane protein zf-C4H2 PF10146.4 ETO20702.1 - 6.7 6.6 11.7 0.13 12.2 1.4 2.2 1 1 1 2 2 2 0 Zinc finger-containing protein Ctr PF04145.10 ETO20703.1 - 0.055 13.5 0.3 0.06 13.4 0.2 1.0 1 0 0 1 1 1 0 Ctr copper transporter family OAD_gamma PF04277.8 ETO20703.1 - 0.073 13.4 0.5 0.092 13.1 0.3 1.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Peroxin-13_N PF04088.8 ETO20703.1 - 0.11 12.4 3.2 0.11 12.4 2.2 1.0 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Cnd1_N PF12922.2 ETO20703.1 - 0.13 11.8 2.9 0.15 11.7 2.0 1.0 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term BLVR PF06375.6 ETO20703.1 - 0.13 12.0 12.8 0.15 11.8 8.9 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Peptidase_S49_N PF08496.5 ETO20703.1 - 0.14 11.9 8.5 0.15 11.8 5.9 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Bap31 PF05529.7 ETO20703.1 - 0.38 10.1 3.1 0.43 10.0 2.2 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF3987 PF13148.1 ETO20703.1 - 0.66 8.4 3.7 0.69 8.4 2.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) ETRAMP PF09716.5 ETO20703.1 - 2.4 8.1 8.9 2.9 7.9 6.2 1.1 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Transglut_C PF00927.17 ETO20704.1 - 0.074 13.1 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain Vac14_Fab1_bd PF12755.2 ETO20705.1 - 0.013 15.8 0.1 1.3 9.5 0.0 3.9 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Clathrin PF00637.15 ETO20706.1 - 0.0045 16.6 1.6 0.067 12.7 0.6 2.4 2 0 0 2 2 2 1 Region in Clathrin and VPS PPR_2 PF13041.1 ETO20706.1 - 0.018 15.0 0.1 0.16 11.9 0.0 2.5 2 0 0 2 2 2 0 PPR repeat family Surface_antigen PF11054.3 ETO20706.1 - 0.021 14.1 1.0 0.036 13.4 0.7 1.4 1 0 0 1 1 1 0 Sporozoite TA4 surface antigen Methyltransf_27 PF13708.1 ETO20706.1 - 0.043 13.3 1.2 0.091 12.2 0.3 1.8 1 1 0 2 2 2 0 Methyltransferase domain Imm35 PF15581.1 ETO20706.1 - 0.056 13.4 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 Immunity protein 35 SopA PF13981.1 ETO20706.1 - 0.059 13.3 2.4 0.068 13.1 0.4 2.0 1 1 1 2 2 2 0 SopA-like central domain DUF327 PF03885.8 ETO20706.1 - 0.072 12.9 4.3 0.11 12.2 1.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF327) Mad3_BUB1_I PF08311.7 ETO20706.1 - 0.1 12.3 2.4 0.22 11.3 1.7 1.6 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 RE_Alw26IDE PF09665.5 ETO20706.1 - 0.21 10.2 6.7 0.27 9.9 4.7 1.3 1 1 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) Phage_int_SAM_5 PF13102.1 ETO20706.1 - 0.57 10.1 7.9 0.57 10.1 3.0 2.3 1 1 1 2 2 2 0 Phage integrase SAM-like domain WD40 PF00400.27 ETO20708.1 - 4e-59 194.5 11.1 2.5e-11 42.9 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat PD40 PF07676.7 ETO20708.1 - 6.2e-08 32.1 8.8 1.9 8.2 0.0 6.4 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Kelch_1 PF01344.20 ETO20708.1 - 1.4e-06 27.7 8.9 0.00012 21.5 0.1 4.2 5 0 0 5 5 5 2 Kelch motif Nup160 PF11715.3 ETO20708.1 - 2.7e-06 25.8 0.6 0.26 9.3 0.1 3.7 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO20708.1 - 0.00021 21.2 9.4 0.042 14.0 0.1 5.5 7 0 0 7 7 7 2 Kelch motif Kelch_4 PF13418.1 ETO20708.1 - 0.00035 20.2 2.1 0.023 14.4 0.0 3.8 4 0 0 4 4 4 1 Galactose oxidase, central domain Cytochrom_D1 PF02239.11 ETO20708.1 - 0.00094 17.5 0.1 0.0032 15.8 0.0 1.9 1 1 0 1 1 1 1 Cytochrome D1 heme domain Resistin PF06954.6 ETO20708.1 - 0.002 18.3 0.0 18 5.6 0.0 3.6 2 1 0 3 3 3 0 Resistin PQQ_2 PF13360.1 ETO20708.1 - 0.0024 17.3 0.1 0.011 15.2 0.1 2.1 1 1 0 1 1 1 1 PQQ-like domain Proteasome_A_N PF10584.4 ETO20708.1 - 0.015 14.6 11.2 7.3 6.0 0.0 5.5 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature Kelch_5 PF13854.1 ETO20708.1 - 0.017 15.0 0.5 8.7 6.4 0.0 3.3 3 0 0 3 3 3 0 Kelch motif WD40 PF00400.27 ETO20709.1 - 1.8e-32 110.0 28.7 7.4e-08 31.9 2.3 7.3 6 2 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO20709.1 - 3e-07 28.9 0.8 0.00095 17.4 0.0 3.5 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO20709.1 - 0.00043 19.1 1.6 0.008 14.9 0.1 2.8 1 1 2 3 3 3 1 Nup133 N terminal like eIF2A PF08662.6 ETO20709.1 - 0.097 12.3 2.4 14 5.3 0.1 3.3 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A Sporozoite_P67 PF05642.6 ETO20710.1 - 0.016 13.0 5.8 0.024 12.5 4.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen LZ_Tnp_IS66 PF13007.2 ETO20711.1 - 0.016 15.8 2.8 0.016 15.8 2.0 2.9 3 1 0 3 3 3 0 Transposase C of IS166 homeodomain GlutR_dimer PF00745.15 ETO20711.1 - 0.025 14.4 0.1 0.065 13.1 0.1 1.7 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain WD40 PF00400.27 ETO20712.1 - 1.6e-14 53.1 5.5 3.5e-11 42.5 0.2 3.5 4 0 0 4 4 4 2 WD domain, G-beta repeat BMF PF15185.1 ETO20712.1 - 0.0037 16.6 1.3 0.0093 15.2 0.9 1.6 1 0 0 1 1 1 1 Bcl-2-modifying factor, apoptosis Claudin_2 PF13903.1 ETO20712.1 - 0.045 13.4 6.9 0.34 10.5 0.2 3.3 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Spc7_N PF15402.1 ETO20712.1 - 6.1 4.7 20.1 1 7.3 10.9 1.7 2 0 0 2 2 2 0 N-terminus of kinetochore NMS complex subunit Spc7 Lipase_GDSL_2 PF13472.1 ETO20713.1 - 0.0039 17.3 0.0 0.0069 16.5 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF2514 PF10721.4 ETO20713.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) RRM_1 PF00076.17 ETO20714.1 - 0.024 14.2 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Macoilin PF09726.4 ETO20714.1 - 0.036 12.3 7.8 0.041 12.1 5.4 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF1517 PF07466.6 ETO20714.1 - 1.6 7.6 10.3 6.1 5.7 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) Corona_nucleoca PF00937.13 ETO20714.1 - 9.2 5.1 11.9 7.8 5.3 3.4 2.3 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein ubiquitin PF00240.18 ETO20715.1 - 0.00024 20.4 0.0 0.00065 19.0 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Peptidase_C70 PF12385.3 ETO20715.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Papain-like cysteine protease AvrRpt2 Rootletin PF15035.1 ETO20716.1 - 0.0012 18.8 1.9 0.0012 18.8 1.3 1.4 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion IncA PF04156.9 ETO20716.1 - 0.027 14.0 2.0 0.031 13.8 1.4 1.2 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 ETO20716.1 - 2 8.7 6.5 0.69 10.2 2.5 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Striatin PF08232.7 ETO20716.1 - 2.1 8.6 6.6 0.92 9.8 2.4 1.9 2 1 0 2 2 2 0 Striatin family AAA_22 PF13401.1 ETO20718.1 - 0.001 19.1 0.7 0.0092 16.1 0.1 2.8 3 1 0 3 3 3 1 AAA domain NTPase_1 PF03266.10 ETO20718.1 - 0.11 12.2 3.1 0.15 11.7 0.7 2.1 2 0 0 2 2 2 0 NTPase SSPI PF14098.1 ETO20718.1 - 0.14 12.1 2.0 0.75 9.7 0.1 2.7 3 0 0 3 3 3 0 Small, acid-soluble spore protein I FAD_binding_3 PF01494.14 ETO20719.1 - 0.00046 19.3 0.0 0.00081 18.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Ribosomal_L7Ae PF01248.21 ETO20719.1 - 0.019 14.4 0.6 0.037 13.5 0.4 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family FAD_binding_3 PF01494.14 ETO20720.1 - 1.1e-06 28.0 0.0 1.2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 ETO20720.1 - 0.00034 19.5 0.0 0.00045 19.1 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase UPRTase PF14681.1 ETO20721.1 - 5e-39 133.6 0.0 7.5e-39 133.0 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 ETO20721.1 - 1.8e-07 30.9 0.1 3.3e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Thoc2 PF11732.3 ETO20723.1 - 0.0046 16.7 0.2 0.0098 15.6 0.1 1.6 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Borrelia_orfA PF02414.10 ETO20724.1 - 0.16 11.0 13.5 0.21 10.6 9.4 1.1 1 0 0 1 1 1 0 Borrelia ORF-A DUF1644 PF07800.7 ETO20725.1 - 0.072 12.9 0.4 0.1 12.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) DUF1077 PF06417.7 ETO20725.1 - 0.22 10.8 1.2 0.34 10.2 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1077) PIP5K PF01504.13 ETO20726.1 - 2.4e-08 33.4 0.1 3.3e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase AA_permease_2 PF13520.1 ETO20726.1 - 0.19 10.1 9.3 0.24 9.9 6.4 1.1 1 0 0 1 1 1 0 Amino acid permease EVC2_like PF12297.3 ETO20726.1 - 4 5.9 5.1 5.2 5.6 3.5 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein cNMP_binding PF00027.24 ETO20727.1 - 3.4e-37 126.1 0.2 4.3e-17 61.7 0.0 3.3 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Pkinase PF00069.20 ETO20727.1 - 1.1e-13 50.9 0.0 2.5e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO20727.1 - 1.1e-05 24.6 0.1 1.8e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 ETO20728.1 - 7.5e-40 136.7 0.0 1.1e-39 136.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO20728.1 - 2e-15 56.5 0.0 3.3e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO20728.1 - 2.9e-06 26.4 0.0 3.9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PEPcase PF00311.12 ETO20728.1 - 0.031 12.1 0.3 0.042 11.6 0.2 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Seadorna_VP7 PF07387.6 ETO20728.1 - 0.073 11.8 0.0 0.098 11.4 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 ETO20728.1 - 0.11 12.2 0.0 1.9 8.1 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family ATP-gua_Ptrans PF00217.14 ETO20730.1 - 1.6e-18 66.9 0.0 2.4e-17 63.0 0.0 2.0 1 1 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain DUF2207 PF09972.4 ETO20731.1 - 0.008 14.8 0.3 0.011 14.3 0.2 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) gag_pre-integrs PF13976.1 ETO20731.1 - 3.5 7.3 5.0 0.4 10.3 0.1 2.1 2 1 0 2 2 2 0 GAG-pre-integrase domain DUF3139 PF11337.3 ETO20731.1 - 3.8 7.8 8.9 4.9 7.5 5.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3139) DUF3302 PF11742.3 ETO20731.1 - 7.3 6.5 9.0 60 3.6 5.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3302) DNA_pol3_gamma3 PF12169.3 ETO20732.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III uDENN PF03456.13 ETO20733.1 - 6.7e-10 38.7 2.7 1.3e-09 37.8 0.6 2.4 2 0 0 2 2 2 1 uDENN domain Peptidase_C37 PF05416.7 ETO20734.1 - 0.0022 16.3 2.6 0.0029 16.0 1.8 1.1 1 0 0 1 1 1 1 Southampton virus-type processing peptidase DUF4611 PF15387.1 ETO20734.1 - 6.8 6.9 16.8 1.1 9.4 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) tRNA-synt_1c PF00749.16 ETO20735.1 - 9.2e-59 198.6 0.0 1.2e-58 198.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 ETO20735.1 - 2.9e-30 105.2 0.0 5.2e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Bgal_small_N PF02929.12 ETO20736.1 - 0.0034 16.4 0.0 0.0042 16.1 0.0 1.2 1 0 0 1 1 1 1 Beta galactosidase small chain Noelin-1 PF12308.3 ETO20736.1 - 0.0064 16.2 1.3 0.01 15.6 0.9 1.4 1 0 0 1 1 1 1 Neurogenesis glycoprotein HTH_30 PF13556.1 ETO20736.1 - 0.0074 15.8 0.1 0.012 15.1 0.1 1.3 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain TBPIP PF07106.8 ETO20736.1 - 0.012 15.2 1.3 0.019 14.5 0.9 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Matrilin_ccoil PF10393.4 ETO20736.1 - 0.016 14.5 3.4 1.2 8.5 0.8 2.3 1 1 1 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin mRNA_cap_enzyme PF01331.14 ETO20736.1 - 0.054 13.1 0.2 0.087 12.5 0.1 1.3 1 0 0 1 1 1 0 mRNA capping enzyme, catalytic domain Fzo_mitofusin PF04799.8 ETO20736.1 - 0.059 12.7 2.3 0.091 12.1 1.6 1.3 1 0 0 1 1 1 0 fzo-like conserved region BLOC1_2 PF10046.4 ETO20736.1 - 0.068 13.3 0.9 0.13 12.4 0.6 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_2 PF07716.10 ETO20736.1 - 0.079 12.8 1.6 2.5 7.9 0.1 2.4 2 0 0 2 2 2 0 Basic region leucine zipper DUF1664 PF07889.7 ETO20736.1 - 0.088 12.6 1.2 0.13 12.0 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) HAUS4 PF14735.1 ETO20736.1 - 0.088 12.0 2.5 0.13 11.5 1.7 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 DUF4404 PF14357.1 ETO20736.1 - 0.11 12.9 2.4 0.15 12.4 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Phasin PF05597.6 ETO20736.1 - 0.16 11.7 1.3 0.24 11.1 0.9 1.3 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) MitMem_reg PF13012.1 ETO20736.1 - 0.19 11.8 1.3 0.35 10.9 0.9 1.5 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Adaptin_N PF01602.15 ETO20737.1 - 2.2e-38 131.9 0.1 2.6e-38 131.6 0.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 ETO20737.1 - 2.6e-08 33.8 0.1 3.4e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 ETO20737.1 - 9.9e-08 32.1 0.0 0.00036 20.7 0.0 2.1 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 ETO20737.1 - 2.4e-05 24.0 2.0 0.42 10.8 0.0 4.0 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 ETO20737.1 - 0.1 13.1 0.1 13 6.4 0.1 3.1 2 2 1 3 3 3 0 HEAT-like repeat RasGEF_N_2 PF14663.1 ETO20737.1 - 0.14 12.0 0.1 0.35 10.8 0.0 1.8 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Arm PF00514.18 ETO20737.1 - 1 9.2 6.7 2.6 8.0 0.0 3.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Myosin_TH1 PF06017.8 ETO20739.1 - 1.3e-16 60.4 1.2 1.9e-16 59.9 0.8 1.2 1 0 0 1 1 1 1 Myosin tail hSac2 PF12456.3 ETO20739.1 - 0.016 14.6 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 Inositol phosphatase bPH_3 PF14470.1 ETO20739.1 - 0.041 14.1 0.9 0.071 13.3 0.6 1.4 1 0 0 1 1 1 0 Bacterial PH domain DUF4247 PF14042.1 ETO20739.1 - 0.046 13.6 0.1 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4247) CTP_transf_2 PF01467.21 ETO20740.1 - 1.2e-08 35.1 0.3 5.6e-08 32.9 0.2 2.0 1 1 0 1 1 1 1 Cytidylyltransferase HemN_C PF06969.11 ETO20741.1 - 0.042 13.9 0.0 0.069 13.2 0.0 1.4 1 0 0 1 1 1 0 HemN C-terminal domain Sec3_C PF09763.4 ETO20741.1 - 0.53 8.3 9.4 0.034 12.2 3.0 1.5 2 0 0 2 2 2 0 Exocyst complex component Sec3 PI3K_C2 PF00792.19 ETO20742.1 - 4.1e-05 23.3 0.0 7.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PolyA_pol_arg_C PF12626.2 ETO20743.1 - 0.29 10.7 0.1 0.29 10.7 0.1 2.4 3 0 0 3 3 3 0 Polymerase A arginine-rich C-terminus Pex14_N PF04695.8 ETO20743.1 - 0.46 10.5 6.6 0.062 13.3 1.5 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NPR3 PF03666.8 ETO20743.1 - 2.7 6.4 10.6 0.06 11.8 2.8 1.4 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Nucleoplasmin PF03066.10 ETO20744.1 - 0.0026 17.3 4.7 0.003 17.0 3.2 1.2 1 0 0 1 1 1 1 Nucleoplasmin Nop14 PF04147.7 ETO20744.1 - 0.0042 15.1 2.2 0.0033 15.4 1.5 1.1 1 0 0 1 1 1 1 Nop14-like family PDCD2_C PF04194.8 ETO20744.1 - 0.012 15.2 4.1 0.29 10.6 0.0 2.2 2 0 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain LRS4 PF10422.4 ETO20744.1 - 0.012 14.9 0.0 0.017 14.5 0.0 1.3 1 1 0 1 1 1 0 Monopolin complex subunit LRS4 Polyoma_coat PF00718.15 ETO20744.1 - 0.05 12.5 0.0 0.062 12.2 0.0 1.2 1 0 0 1 1 1 0 Polyomavirus coat protein Dicty_REP PF05086.7 ETO20744.1 - 0.086 10.5 2.5 0.12 10.1 1.7 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sigma70_ner PF04546.8 ETO20744.1 - 0.093 12.3 7.3 0.15 11.6 5.1 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region HSP90 PF00183.13 ETO20744.1 - 0.1 11.0 5.1 0.15 10.3 3.5 1.2 1 0 0 1 1 1 0 Hsp90 protein Myc_N PF01056.13 ETO20744.1 - 0.28 10.2 5.7 0.39 9.8 3.9 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Sporozoite_P67 PF05642.6 ETO20744.1 - 0.3 8.8 3.5 0.36 8.6 2.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Daxx PF03344.10 ETO20744.1 - 0.36 9.2 7.5 0.43 8.9 5.2 1.1 1 0 0 1 1 1 0 Daxx Family CENP-B_dimeris PF09026.5 ETO20744.1 - 0.69 10.1 10.9 1.2 9.4 7.6 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.1 ETO20744.1 - 0.72 9.5 3.4 1.1 8.9 2.3 1.2 1 0 0 1 1 1 0 FAM176 family Paf1 PF03985.8 ETO20744.1 - 1.5 7.4 9.2 2.1 7.0 6.4 1.1 1 0 0 1 1 1 0 Paf1 Med2 PF11214.3 ETO20744.1 - 1.5 8.8 6.8 0.94 9.5 1.8 2.1 2 0 0 2 2 2 0 Mediator complex subunit 2 CDC45 PF02724.9 ETO20744.1 - 2.8 5.8 7.9 3.9 5.3 5.5 1.1 1 0 0 1 1 1 0 CDC45-like protein AF1Q PF15017.1 ETO20744.1 - 3.5 7.5 10.3 7.1 6.6 7.1 1.4 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator Prothymosin PF03247.9 ETO20744.1 - 4.3 7.5 22.9 0.48 10.5 11.8 2.0 2 0 0 2 2 2 0 Prothymosin/parathymosin family VID27 PF08553.5 ETO20744.1 - 4.7 5.3 8.0 6.3 4.8 5.6 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein BSP_II PF05432.6 ETO20744.1 - 5 6.3 14.7 7.1 5.8 10.2 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) NOA36 PF06524.7 ETO20744.1 - 5.6 6.1 8.2 7.9 5.6 5.7 1.2 1 0 0 1 1 1 0 NOA36 protein CDV3 PF15359.1 ETO20744.1 - 6.5 6.8 8.3 11 6.0 5.8 1.3 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 CobT PF06213.7 ETO20744.1 - 9.5 5.2 14.2 14 4.7 9.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2457 PF10446.4 ETO20744.1 - 9.8 4.7 11.1 13 4.3 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF2457 PF10446.4 ETO20745.1 - 8.8 4.9 28.6 0.68 8.5 13.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Glyco_transf_49 PF13896.1 ETO20747.1 - 4.1e-26 91.8 0.4 2.9e-23 82.4 0.3 2.1 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 ETO20747.1 - 1e-05 24.7 0.0 1.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 ETO20747.1 - 0.00086 19.0 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 CLPTM1 PF05602.7 ETO20748.1 - 2e-115 386.0 7.2 2e-114 382.6 5.0 1.9 1 1 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) MtN3_slv PF03083.11 ETO20748.1 - 0.0023 17.7 2.5 0.0023 17.7 1.7 1.9 2 0 0 2 2 2 1 Sugar efflux transporter for intercellular exchange DUF788 PF05620.6 ETO20748.1 - 1.7 8.4 5.2 1.4 8.7 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF788) G-alpha PF00503.15 ETO20749.1 - 4.3e-28 98.0 0.4 5.1e-28 97.8 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit DUF1281 PF06924.6 ETO20749.1 - 0.059 12.7 0.0 0.3 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1281) G-alpha PF00503.15 ETO20750.1 - 3.2e-50 170.9 0.7 3.8e-50 170.7 0.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO20750.1 - 0.0004 19.6 0.0 0.00064 19.0 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family zf-HC5HC2H_2 PF13832.1 ETO20750.1 - 0.051 13.5 3.3 1.8 8.6 1.0 2.2 2 0 0 2 2 2 0 PHD-zinc-finger like domain WD40 PF00400.27 ETO20751.1 - 7.2e-55 181.0 29.4 3.6e-12 45.6 0.3 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO20751.1 - 4.5e-08 31.6 8.4 0.035 12.2 0.0 4.8 2 1 2 4 4 4 4 Nucleoporin Nup120/160 CPG4 PF15481.1 ETO20751.1 - 0.068 13.5 0.8 0.15 12.3 0.5 1.6 1 0 0 1 1 1 0 Chondroitin proteoglycan 4 DUF3925 PF13063.1 ETO20752.1 - 0.18 11.8 0.7 0.6 10.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3925) GHMP_kinases_C PF08544.8 ETO20753.1 - 3.7e-10 39.8 0.0 4.8e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 GHMP kinases C terminal Phage_gp49_66 PF13876.1 ETO20753.1 - 0.12 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Phage protein (N4 Gp49/phage Sf6 gene 66) family Pkinase_C PF00433.19 ETO20754.1 - 0.0044 17.4 3.4 0.035 14.6 2.3 2.4 1 1 0 1 1 1 1 Protein kinase C terminal domain XK-related PF09815.4 ETO20755.1 - 1.4e-08 34.1 21.2 7.1e-08 31.8 14.7 2.1 1 1 0 1 1 1 1 XK-related protein DUF3751 PF12571.3 ETO20755.1 - 0.23 11.2 0.3 4.3 7.1 0.0 2.6 2 1 1 3 3 3 0 Phage tail-collar fibre protein Kelch_6 PF13964.1 ETO20756.1 - 0.0012 18.8 0.4 1.4 9.2 0.0 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO20756.1 - 0.016 14.6 2.9 2.7 7.6 0.0 3.4 3 0 0 3 3 3 0 Kelch motif zf-RING_2 PF13639.1 ETO20757.1 - 1.2e-10 41.0 7.3 2.6e-10 39.9 5.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 ETO20757.1 - 6.8e-08 32.5 5.4 1.5e-07 31.4 3.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 ETO20757.1 - 0.00052 19.6 8.1 0.0015 18.1 5.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO20757.1 - 0.0011 18.9 9.5 0.0011 18.9 6.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 ETO20757.1 - 0.0031 17.4 9.1 0.0031 17.4 6.3 1.8 2 0 0 2 2 2 1 RING-variant domain zf-Apc11 PF12861.2 ETO20757.1 - 0.0078 16.0 2.1 0.018 14.9 1.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 ETO20757.1 - 0.01 15.5 9.2 0.027 14.1 6.4 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-LITAF-like PF10601.4 ETO20757.1 - 0.047 13.5 0.4 0.047 13.5 0.3 2.2 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain zf-C3HC4 PF00097.20 ETO20757.1 - 0.42 10.2 15.0 0.063 12.9 6.9 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 ETO20757.1 - 0.45 10.3 4.4 2.1 8.2 1.5 2.5 2 1 0 2 2 2 0 Double zinc ribbon FANCL_C PF11793.3 ETO20757.1 - 0.66 9.9 9.1 49 3.9 6.3 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain Rad50_zn_hook PF04423.9 ETO20757.1 - 6.8 6.2 11.1 0.74 9.3 1.9 2.8 3 0 0 3 3 3 0 Rad50 zinc hook motif Dus PF01207.12 ETO20758.1 - 1e-27 96.7 0.0 1.1e-27 96.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Oxidored_FMN PF00724.15 ETO20758.1 - 0.028 13.4 0.0 0.037 13.0 0.0 1.1 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.16 ETO20758.1 - 0.15 11.3 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein DUF912 PF06024.7 ETO20759.1 - 1.5 8.8 4.3 0.25 11.4 0.4 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Staphostatin_A PF09022.5 ETO20760.1 - 0.21 11.4 3.0 0.36 10.6 0.6 2.5 1 1 2 3 3 3 0 Staphostatin A LRR_4 PF12799.2 ETO20761.1 - 6e-07 28.9 21.1 3.7e-06 26.4 4.7 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO20761.1 - 9.2e-05 22.1 13.1 0.00021 20.9 2.2 2.9 1 1 2 3 3 3 3 Leucine rich repeat ACT_4 PF13291.1 ETO20761.1 - 0.11 12.9 1.4 9.1 6.6 0.1 2.3 2 0 0 2 2 2 0 ACT domain LRR_6 PF13516.1 ETO20761.1 - 0.24 11.6 8.7 3.9 7.8 0.7 3.8 3 0 0 3 3 3 0 Leucine Rich repeat LRR_7 PF13504.1 ETO20761.1 - 0.42 10.9 9.7 43 4.9 0.7 4.5 3 1 0 3 3 3 0 Leucine rich repeat Recep_L_domain PF01030.19 ETO20761.1 - 1 9.3 8.6 0.35 10.8 1.3 2.3 1 1 1 2 2 2 0 Receptor L domain LRR_1 PF00560.28 ETO20761.1 - 1.6 9.0 22.1 2.6 8.4 0.6 4.7 4 2 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.2 ETO20762.1 - 4.7e-08 32.4 14.8 1.8e-06 27.3 4.7 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO20762.1 - 7.9e-05 22.3 11.7 9.3e-05 22.1 2.2 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 ETO20762.1 - 0.0033 17.2 15.1 1.6 9.0 0.6 4.1 3 1 0 3 3 3 3 Leucine Rich Repeat LRR_6 PF13516.1 ETO20762.1 - 0.063 13.3 8.1 2.4 8.5 0.7 3.5 3 0 0 3 3 3 0 Leucine Rich repeat LRR_7 PF13504.1 ETO20762.1 - 0.24 11.7 10.3 21 5.9 0.4 4.1 3 1 1 4 4 4 0 Leucine rich repeat U-box PF04564.10 ETO20763.1 - 1.2e-10 41.1 0.0 4.2e-10 39.4 0.0 2.0 1 0 0 1 1 1 1 U-box domain Kelch_1 PF01344.20 ETO20763.1 - 1.3e-06 27.7 4.3 0.0026 17.2 0.1 2.7 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.1 ETO20763.1 - 4.5e-06 26.5 4.0 0.011 15.8 0.1 3.2 2 1 1 3 3 3 2 Kelch motif Kelch_3 PF13415.1 ETO20763.1 - 0.0016 18.5 0.2 0.52 10.5 0.0 3.3 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO20763.1 - 0.21 11.4 3.5 22 5.0 0.5 3.4 3 0 0 3 3 3 0 Kelch motif CAP_GLY PF01302.20 ETO20764.1 - 6e-17 61.1 0.7 1.2e-16 60.1 0.5 1.5 1 0 0 1 1 1 1 CAP-Gly domain SH3_9 PF14604.1 ETO20764.1 - 0.094 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Pkinase PF00069.20 ETO20769.1 - 1.9e-66 223.8 0.0 3.8e-66 222.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO20769.1 - 2.3e-31 108.7 0.0 4.5e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO20769.1 - 0.00038 19.5 0.0 0.00098 18.1 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 ETO20769.1 - 0.026 13.3 0.5 0.055 12.2 0.3 1.5 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 ETO20769.1 - 0.039 13.0 0.0 0.12 11.3 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO20769.1 - 0.17 11.5 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Rubrerythrin PF02915.12 ETO20772.1 - 0.0069 16.7 2.4 0.012 15.9 1.6 1.2 1 0 0 1 1 1 1 Rubrerythrin MutS_III PF05192.13 ETO20772.1 - 0.033 13.9 0.3 0.042 13.6 0.2 1.2 1 0 0 1 1 1 0 MutS domain III GTPase_Cys_C PF12631.2 ETO20772.1 - 0.11 12.9 0.6 3.6 8.0 0.0 2.7 1 1 1 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE DUF912 PF06024.7 ETO20772.1 - 0.34 10.9 4.2 13 5.8 0.0 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3053 PF11254.3 ETO20773.1 - 0.045 12.9 6.9 0.083 12.1 4.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3053) ATG16 PF08614.6 ETO20773.1 - 0.72 9.6 16.2 0.31 10.8 6.5 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF972 PF06156.8 ETO20773.1 - 5.2 7.4 15.8 1.2 9.4 6.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF641 PF04859.7 ETO20773.1 - 5.7 6.7 15.6 0.066 12.9 4.2 2.3 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) Tom37_C PF11801.3 ETO20774.1 - 3.1 7.6 6.4 1.3 8.8 2.2 2.0 2 0 0 2 2 2 0 Tom37 C-terminal domain Coprogen_oxidas PF01218.13 ETO20776.1 - 9.7e-101 336.2 0.1 1.3e-100 335.8 0.0 1.2 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase SNARE PF05739.14 ETO20777.1 - 3.8e-06 26.5 5.6 1.5e-05 24.5 3.9 2.1 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.1 ETO20777.1 - 0.008 16.1 7.3 0.008 16.1 5.1 2.3 3 0 0 3 3 2 1 Syntaxin-like protein Laminin_II PF06009.7 ETO20777.1 - 0.0085 15.8 7.0 0.081 12.6 0.7 2.5 2 0 0 2 2 2 2 Laminin Domain II DUF241 PF03087.9 ETO20777.1 - 0.018 14.5 8.4 0.05 13.0 5.8 1.7 1 1 0 1 1 1 0 Arabidopsis protein of unknown function Baculo_LEF-2 PF03041.9 ETO20777.1 - 0.071 12.7 1.2 0.25 10.9 0.1 2.1 2 0 0 2 2 2 0 lef-2 AAA_5 PF07728.9 ETO20777.1 - 0.079 12.6 0.4 0.16 11.7 0.3 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MCPsignal PF00015.16 ETO20777.1 - 0.083 12.4 6.1 1.8 8.0 0.1 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Hormone_3 PF00159.13 ETO20777.1 - 0.11 12.5 0.1 2.1 8.3 0.0 2.6 2 0 0 2 2 2 0 Pancreatic hormone peptide DUF3829 PF12889.2 ETO20777.1 - 0.32 10.1 9.5 0.092 11.9 3.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3829) Filo_VP35 PF02097.10 ETO20777.1 - 0.45 9.6 4.2 1.7 7.8 0.1 2.1 2 0 0 2 2 2 0 Filoviridae VP35 CCDC-167 PF15188.1 ETO20777.1 - 2.3 8.2 7.4 0.86 9.5 0.1 3.2 2 2 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF2762 PF10960.3 ETO20777.1 - 3.1 7.5 11.0 0.79 9.4 1.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2762) BLOC1_2 PF10046.4 ETO20777.1 - 3.5 7.8 13.5 0.5 10.5 2.0 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4591 PF15261.1 ETO20777.1 - 4.5 7.5 12.6 9.4 6.5 7.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4591) DUF948 PF06103.6 ETO20777.1 - 6.1 6.7 8.6 15 5.4 0.8 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF607 PF04678.8 ETO20777.1 - 8.6 6.2 7.9 3 7.7 1.4 2.5 1 1 0 2 2 2 0 Protein of unknown function, DUF607 TPR_12 PF13424.1 ETO20778.1 - 5.3e-93 305.0 29.8 8.5e-22 76.8 0.6 7.2 4 3 3 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.1 ETO20778.1 - 7.1e-54 178.3 0.0 4.2e-09 36.0 0.0 9.6 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.1 ETO20778.1 - 8e-48 159.9 45.6 1.3e-11 43.9 1.8 5.9 3 1 4 7 7 7 7 TPR repeat TPR_7 PF13176.1 ETO20778.1 - 4.3e-46 151.0 13.1 1e-05 24.9 0.1 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_1 PF00515.23 ETO20778.1 - 1.2e-44 148.0 41.6 3.1e-08 32.8 0.1 9.0 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.12 ETO20778.1 - 8.4e-39 128.3 39.1 8.2e-06 25.3 0.5 10.3 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_8 PF13181.1 ETO20778.1 - 7.7e-29 97.2 45.3 0.00017 21.1 0.1 9.7 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_17 PF13431.1 ETO20778.1 - 3.1e-16 58.1 15.8 0.11 12.7 0.1 8.2 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 ETO20778.1 - 7.1e-14 52.0 2.9 0.13 13.0 0.0 6.0 3 1 3 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 ETO20778.1 - 1.7e-12 46.7 0.3 0.96 10.2 0.0 7.9 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO20778.1 - 8.6e-09 35.2 22.5 0.61 10.6 0.1 9.1 9 0 0 9 9 9 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO20778.1 - 7.2e-06 26.0 30.7 0.031 14.4 1.9 5.9 2 2 3 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO20778.1 - 0.0017 18.6 8.7 0.66 10.3 0.9 5.5 5 1 0 5 5 4 1 Tetratricopeptide repeat PPR PF01535.15 ETO20778.1 - 0.0052 16.6 14.0 0.69 10.0 0.0 6.4 8 0 0 8 8 8 2 PPR repeat Fis1_TPR_C PF14853.1 ETO20778.1 - 0.0063 16.3 19.1 1.7 8.6 0.9 6.0 5 0 0 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.4 ETO20778.1 - 0.008 15.3 2.0 18 4.6 0.0 5.4 6 0 0 6 6 6 0 SHNi-TPR TPR_9 PF13371.1 ETO20778.1 - 0.12 12.2 0.0 11 5.9 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 ETO20778.1 - 0.23 11.3 28.1 0.62 9.9 0.1 8.4 10 0 0 10 10 9 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 ETO20778.1 - 5 7.0 30.7 1.7 8.5 0.7 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat WD40 PF00400.27 ETO20779.1 - 3.1e-46 153.6 8.0 1.5e-11 43.6 0.4 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO20779.1 - 3.4e-07 28.8 2.7 0.022 12.9 0.1 3.9 1 1 3 4 4 4 3 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO20779.1 - 2.5e-06 27.7 2.0 8.7e-06 26.0 1.0 2.4 1 1 0 1 1 1 1 TRAF-type zinc finger DUF812 PF05667.6 ETO20779.1 - 0.39 9.1 16.7 0.6 8.5 11.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TPR_MLP1_2 PF07926.7 ETO20779.1 - 0.71 9.6 17.3 0.75 9.5 4.4 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Adeno_E3_CR1 PF02440.10 ETO20780.1 - 0.42 10.1 3.0 0.51 9.8 0.0 2.6 3 0 0 3 3 3 0 Adenovirus E3 region protein CR1 Prothymosin PF03247.9 ETO20781.1 - 1.7 8.8 17.0 2.8 8.1 11.8 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family Menin PF05053.8 ETO20781.1 - 2.5 6.1 9.5 2.4 6.2 6.6 1.0 1 0 0 1 1 1 0 Menin Apis_Csd PF11671.3 ETO20781.1 - 2.8 7.7 15.6 3.4 7.4 10.8 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein DUF2407_C PF13373.1 ETO20781.1 - 4.8 7.1 6.8 5.1 7.0 4.7 1.1 1 0 0 1 1 1 0 DUF2407 C-terminal domain Rtf2 PF04641.7 ETO20782.1 - 0.00052 19.3 13.7 0.00058 19.1 9.5 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger EF-hand_1 PF00036.27 ETO20782.1 - 0.0016 17.6 0.9 0.0029 16.7 0.2 1.8 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 ETO20782.1 - 0.0016 18.5 1.1 0.0029 17.7 0.7 1.6 1 1 0 1 1 1 1 EF-hand domain pair RNase_H2-Ydr279 PF09468.5 ETO20782.1 - 0.0052 16.0 12.8 0.0058 15.8 8.9 1.2 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) GAGA_bind PF06217.7 ETO20782.1 - 0.0066 16.4 9.1 0.0066 16.4 6.3 1.1 1 0 0 1 1 1 1 GAGA binding protein-like family SspB PF04386.8 ETO20782.1 - 0.0086 15.6 5.5 0.011 15.3 3.8 1.2 1 0 0 1 1 1 1 Stringent starvation protein B EF-hand_6 PF13405.1 ETO20782.1 - 0.012 15.3 1.4 0.025 14.4 0.6 1.8 2 0 0 2 2 2 0 EF-hand domain DUF2828 PF11443.3 ETO20782.1 - 0.018 13.2 6.8 0.018 13.2 4.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) EF-hand_5 PF13202.1 ETO20782.1 - 0.035 13.4 0.3 0.061 12.6 0.2 1.4 1 0 0 1 1 1 0 EF hand U79_P34 PF03064.11 ETO20782.1 - 0.13 11.7 13.1 0.14 11.6 9.1 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CDC45 PF02724.9 ETO20782.1 - 0.18 9.8 11.3 0.18 9.8 7.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.17 ETO20782.1 - 0.19 10.6 1.1 0.22 10.4 0.8 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter DDHD PF02862.12 ETO20782.1 - 0.38 10.5 10.7 0.43 10.3 7.4 1.1 1 0 0 1 1 1 0 DDHD domain Serinc PF03348.10 ETO20782.1 - 0.38 9.4 3.7 0.43 9.2 2.6 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) AAA_11 PF13086.1 ETO20782.1 - 0.44 10.0 8.6 0.5 9.9 5.9 1.1 1 0 0 1 1 1 0 AAA domain PRP21_like_P PF12230.3 ETO20782.1 - 0.53 9.7 20.9 0.68 9.4 14.5 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein DUF1510 PF07423.6 ETO20782.1 - 0.62 9.3 18.7 0.73 9.1 13.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF1943 PF09172.6 ETO20782.1 - 0.62 8.8 6.6 0.62 8.8 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Ycf1 PF05758.7 ETO20782.1 - 0.66 7.6 12.8 0.66 7.6 8.9 1.1 1 0 0 1 1 1 0 Ycf1 DUF3381 PF11861.3 ETO20782.1 - 0.89 9.0 25.0 1.5 8.3 17.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Tom37_C PF11801.3 ETO20782.1 - 0.96 9.2 8.2 1.2 8.9 5.7 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain Mem_trans PF03547.13 ETO20782.1 - 1.4 7.1 3.6 1.4 7.0 2.5 1.0 1 0 0 1 1 1 0 Membrane transport protein Folate_carrier PF01770.13 ETO20782.1 - 1.9 6.9 4.7 2.3 6.6 3.3 1.2 1 0 0 1 1 1 0 Reduced folate carrier DUF2201_N PF13203.1 ETO20782.1 - 2.6 7.1 9.4 2.8 7.0 6.5 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Herpes_DNAp_acc PF04929.7 ETO20782.1 - 3.3 6.5 11.8 4 6.2 8.2 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Neur_chan_memb PF02932.11 ETO20782.1 - 4 7.2 6.3 4.1 7.2 4.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.7 ETO20782.1 - 4.8 6.9 18.8 5.4 6.8 13.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 YqfQ PF14181.1 ETO20782.1 - 4.9 7.1 22.5 7.3 6.6 15.6 1.3 1 0 0 1 1 1 0 YqfQ-like protein GCD14 PF08704.5 ETO20782.1 - 5.2 6.4 7.2 6.3 6.2 5.0 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Oxidored_q1_C PF01010.14 ETO20782.1 - 5.7 6.3 6.5 7.6 5.9 4.5 1.2 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus PIP5K PF01504.13 ETO20783.1 - 5.6e-48 163.2 0.2 7.5e-48 162.8 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase PIP5K PF01504.13 ETO20784.1 - 4e-09 35.9 0.1 4.7e-09 35.7 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Dicty_REP PF05086.7 ETO20784.1 - 5.8 4.5 11.1 7.3 4.2 7.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Drf_GBD PF06371.8 ETO20785.1 - 3.5e-20 72.1 1.3 7.7e-20 71.0 0.9 1.6 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain PH PF00169.24 ETO20785.1 - 6e-06 26.3 4.8 1.2e-05 25.4 0.1 2.8 3 0 0 3 3 3 1 PH domain CobT PF06213.7 ETO20785.1 - 0.00039 19.6 3.9 0.00039 19.6 2.7 1.5 2 0 0 2 2 2 1 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 ETO20785.1 - 0.002 16.1 7.7 0.0032 15.5 5.3 1.2 1 0 0 1 1 1 1 Nop14-like family CENP-B_dimeris PF09026.5 ETO20785.1 - 0.024 14.8 0.0 0.024 14.8 0.0 2.4 1 1 1 2 2 1 0 Centromere protein B dimerisation domain Sporozoite_P67 PF05642.6 ETO20785.1 - 0.033 12.0 7.6 0.052 11.4 5.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DAHP_synth_1 PF00793.15 ETO20785.1 - 0.087 11.5 0.7 0.73 8.4 0.0 2.1 2 0 0 2 2 2 0 DAHP synthetase I family Sigma70_ner PF04546.8 ETO20785.1 - 0.47 10.0 9.5 0.32 10.5 5.0 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region SDA1 PF05285.7 ETO20785.1 - 0.64 9.2 12.5 1.1 8.5 8.7 1.2 1 0 0 1 1 1 0 SDA1 Utp14 PF04615.8 ETO20785.1 - 2.7 6.0 12.7 4.3 5.3 8.8 1.2 1 0 0 1 1 1 0 Utp14 protein SGT1 PF07093.6 ETO20785.1 - 4.4 5.5 17.4 5.7 5.1 8.6 2.2 2 0 0 2 2 2 0 SGT1 protein FPL PF09758.4 ETO20786.1 - 1.8e-51 173.8 16.2 2.9e-50 169.9 10.3 2.6 2 1 0 2 2 2 1 Uncharacterised conserved protein RAI16-like PF10257.4 ETO20786.1 - 0.069 12.0 0.6 0.21 10.4 0.4 1.9 1 1 0 1 1 1 0 Retinoic acid induced 16-like protein Menin PF05053.8 ETO20787.1 - 0.074 11.2 4.5 0.072 11.2 3.1 1.1 1 0 0 1 1 1 0 Menin UPF0565 PF10561.4 ETO20787.1 - 0.34 9.7 9.9 9.5 5.0 6.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 Ctr PF04145.10 ETO20787.1 - 0.41 10.6 4.1 1.1 9.2 1.4 2.1 2 0 0 2 2 2 0 Ctr copper transporter family Di19_C PF14571.1 ETO20787.1 - 0.74 10.1 18.9 3.2 8.0 7.5 2.2 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal Serinc PF03348.10 ETO20787.1 - 0.94 8.1 4.5 0.23 10.1 0.5 1.7 2 0 0 2 2 2 0 Serine incorporator (Serinc) POX PF07526.6 ETO20787.1 - 1.7 8.8 9.8 6.3 7.0 5.0 2.1 2 0 0 2 2 2 0 Associated with HOX NOA36 PF06524.7 ETO20787.1 - 2.3 7.4 8.3 0.17 11.1 2.5 1.4 2 0 0 2 2 2 0 NOA36 protein Peroxin-13_N PF04088.8 ETO20787.1 - 3.6 7.5 9.7 3.7 7.4 0.1 2.4 2 1 0 2 2 2 0 Peroxin 13, N-terminal region NRDE-2 PF08424.5 ETO20787.1 - 3.9 6.2 9.9 6.3 5.5 6.9 1.3 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Striatin PF08232.7 ETO20787.1 - 4.6 7.5 10.5 1.5 9.1 3.7 2.1 2 0 0 2 2 2 0 Striatin family RP-C_C PF11800.3 ETO20787.1 - 5.4 6.6 10.5 1.9 8.1 4.1 2.0 2 0 0 2 2 2 0 Replication protein C C-terminal region Gti1_Pac2 PF09729.4 ETO20787.1 - 6.3 6.6 10.2 10 5.9 5.4 2.0 2 0 0 2 2 2 0 Gti1/Pac2 family DUF1510 PF07423.6 ETO20787.1 - 6.5 6.0 16.0 0.28 10.4 5.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) FAM60A PF15396.1 ETO20787.1 - 7.1 6.3 10.7 5.8 6.6 3.8 2.0 2 0 0 2 2 2 0 Protein Family FAM60A Zip PF02535.17 ETO20787.1 - 8.8 5.2 6.8 16 4.3 4.7 1.6 1 1 0 1 1 1 0 ZIP Zinc transporter FAM176 PF14851.1 ETO20787.1 - 9.7 5.8 10.6 22 4.7 5.6 2.3 2 1 0 2 2 2 0 FAM176 family WD40 PF00400.27 ETO20788.1 - 1.5e-25 88.0 13.7 7.9e-08 31.9 0.4 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO20788.1 - 1.8e-05 23.0 3.9 0.11 10.5 0.0 2.9 2 1 1 3 3 3 3 Nucleoporin Nup120/160 C1_2 PF03107.11 ETO20789.1 - 0.0058 16.7 0.2 0.0058 16.7 0.1 3.4 3 0 0 3 3 3 1 C1 domain DUF241 PF03087.9 ETO20791.1 - 0.0056 16.1 4.0 0.032 13.7 0.1 2.0 1 1 1 2 2 2 2 Arabidopsis protein of unknown function Pox_H7 PF04787.7 ETO20791.1 - 0.024 14.4 0.6 0.024 14.4 0.4 1.5 1 1 1 2 2 2 0 Late protein H7 EST1 PF10374.4 ETO20791.1 - 1.9 8.4 6.2 8.5 6.3 3.6 2.2 1 1 0 1 1 1 0 Telomerase activating protein Est1 Elongin_A PF06881.6 ETO20791.1 - 5.8 7.3 6.5 29 5.1 4.5 2.0 1 1 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Peptidase_C14 PF00656.17 ETO20793.1 - 2.9e-15 56.6 1.0 4.5e-15 56.0 0.7 1.3 1 0 0 1 1 1 1 Caspase domain Apc3 PF12895.2 ETO20794.1 - 0.0013 18.8 1.5 0.002 18.2 0.8 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 Fer2_3 PF13085.1 ETO20794.1 - 0.062 13.1 0.1 0.79 9.5 0.0 2.0 1 1 1 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Pam16 PF03656.8 ETO20794.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Pam16 Choline_transpo PF04515.7 ETO20795.1 - 1.7e-76 257.1 20.1 2.2e-76 256.7 14.0 1.0 1 0 0 1 1 1 1 Plasma-membrane choline transporter Transport_MerF PF11431.3 ETO20795.1 - 0.11 12.2 4.0 8.1 6.1 0.7 2.8 2 0 0 2 2 2 0 Membrane transport protein MerF ScpA_ScpB PF02616.9 ETO20796.1 - 0.033 13.7 1.3 0.066 12.7 0.9 1.6 1 0 0 1 1 1 0 ScpA/B protein DUF4270 PF14092.1 ETO20796.1 - 0.17 10.4 8.0 0.25 9.9 5.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4270) Ras PF00071.17 ETO20797.1 - 9e-31 106.4 2.2 1e-30 106.2 1.6 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO20797.1 - 3.9e-11 43.4 0.1 6.2e-11 42.8 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO20797.1 - 1.3e-10 40.8 0.1 1.8e-10 40.3 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.4 ETO20797.1 - 0.00054 19.4 0.4 0.03 13.8 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 ETO20797.1 - 0.0065 15.5 0.0 2.4 7.0 0.0 2.1 2 0 0 2 2 2 2 Septin MMR_HSR1 PF01926.18 ETO20797.1 - 0.018 15.0 0.0 0.033 14.1 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.13 ETO20797.1 - 0.026 13.7 0.2 1.4 8.1 0.0 2.2 3 0 0 3 3 3 0 Ferrous iron transport protein B GTP_EFTU PF00009.22 ETO20797.1 - 0.034 13.5 0.6 0.35 10.2 0.4 2.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF1371 PF07115.6 ETO20797.1 - 0.094 12.8 3.4 0.067 13.3 0.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1371) Ish1 PF10281.4 ETO20797.1 - 1.5 8.9 6.1 4.8 7.3 0.3 2.7 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein B56 PF01603.15 ETO20798.1 - 2.1e-139 464.6 13.2 2.7e-139 464.3 9.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Claudin_2 PF13903.1 ETO20800.1 - 0.037 13.7 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Annexin PF00191.15 ETO20801.1 - 1.3e-24 85.9 0.3 1.8e-05 24.5 0.1 4.2 4 0 0 4 4 4 4 Annexin GNAT_acetyltran PF12746.2 ETO20801.1 - 0.061 12.1 0.1 0.09 11.5 0.1 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase DUF2202 PF09968.4 ETO20801.1 - 0.077 12.6 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein domain (DUF2202) DUF872 PF05915.7 ETO20803.1 - 0.19 11.5 6.3 0.81 9.5 0.8 2.5 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Claudin_2 PF13903.1 ETO20803.1 - 3.1 7.4 13.8 67 3.1 9.4 2.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction IBR PF01485.16 ETO20804.1 - 0.00023 20.9 10.4 0.00023 20.9 7.2 3.2 2 1 1 3 3 3 1 IBR domain zf-C2H2_jaz PF12171.3 ETO20804.1 - 0.0031 17.6 0.5 0.31 11.2 0.0 3.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-RING_5 PF14634.1 ETO20804.1 - 0.0031 17.1 8.7 0.0031 17.1 6.0 3.2 2 1 0 2 2 2 1 zinc-RING finger domain Luciferase_cat PF10285.4 ETO20805.1 - 0.083 12.0 0.0 0.27 10.3 0.0 1.7 1 1 1 2 2 2 0 Luciferase catalytic domain Tetraspannin PF00335.15 ETO20806.1 - 3.6e-24 85.2 19.8 4.5e-24 84.9 13.7 1.0 1 0 0 1 1 1 1 Tetraspanin family SLAC1 PF03595.12 ETO20806.1 - 0.012 14.3 9.1 0.014 14.0 3.5 2.0 2 0 0 2 2 2 0 Voltage-dependent anion channel DUF3087 PF11286.3 ETO20806.1 - 0.23 10.7 1.8 0.36 10.0 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) DUF805 PF05656.9 ETO20806.1 - 5.7 6.8 10.0 47 3.8 6.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF805) DUF1625 PF07787.7 ETO20806.1 - 5.9 6.0 7.1 9.4 5.4 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) DUF912 PF06024.7 ETO20806.1 - 6.2 6.9 0.0 6.2 6.9 0.0 3.4 2 1 2 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) HEAT_EZ PF13513.1 ETO20807.1 - 2.9e-08 33.9 0.0 0.00011 22.5 0.0 2.8 2 0 0 2 2 2 2 HEAT-like repeat Adeno_E3B PF03376.9 ETO20807.1 - 0.014 15.2 0.1 3.9 7.4 0.0 2.5 2 0 0 2 2 2 0 Adenovirus E3B protein Phospholip_A2_3 PF09056.6 ETO20807.1 - 0.041 14.1 0.1 0.081 13.1 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic phospholipase A2 HEAT_2 PF13646.1 ETO20807.1 - 0.071 13.3 0.0 7.7 6.8 0.0 3.0 3 1 0 3 3 3 0 HEAT repeats HEAT PF02985.17 ETO20807.1 - 1.6 9.0 0.0 1.6 9.0 0.0 4.0 5 0 0 5 5 5 0 HEAT repeat TFIIE_alpha PF02002.12 ETO20808.1 - 0.0034 16.8 4.5 0.27 10.7 0.5 2.6 2 1 1 3 3 3 3 TFIIE alpha subunit DUF2497 PF10691.4 ETO20808.1 - 0.014 15.3 0.0 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) DUF507 PF04368.8 ETO20808.1 - 0.026 14.1 2.6 0.026 14.1 1.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF507) DUF1786 PF08735.5 ETO20808.1 - 0.16 11.0 3.1 1.1 8.4 0.1 2.1 2 0 0 2 2 2 0 Putative pyruvate format-lyase activating enzyme (DUF1786) GLTSCR1 PF15249.1 ETO20808.1 - 2.2 8.4 5.8 2 8.5 1.7 2.4 1 1 1 2 2 2 0 Glioma tumor suppressor candidate region Ank_2 PF12796.2 ETO20810.1 - 0.0063 16.8 0.3 7.1 7.0 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Zip PF02535.17 ETO20811.1 - 0.0032 16.5 12.0 0.0039 16.2 8.3 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter CDC45 PF02724.9 ETO20811.1 - 2.4 6.0 15.7 3.5 5.5 10.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Menin PF05053.8 ETO20811.1 - 8 4.4 14.1 11 4.0 9.8 1.1 1 0 0 1 1 1 0 Menin SelP_N PF04592.9 ETO20811.1 - 8.3 5.7 35.8 10 5.4 22.6 2.4 2 1 0 2 2 2 0 Selenoprotein P, N terminal region YL1 PF05764.8 ETO20813.1 - 0.005 16.4 20.4 0.005 16.4 14.1 5.7 4 1 1 5 5 5 2 YL1 nuclear protein Kei1 PF08552.6 ETO20813.1 - 3.9 7.0 0.0 3.9 7.0 0.0 6.3 5 2 0 6 6 6 0 Inositolphosphorylceramide synthase subunit Kei1 Med26 PF08711.6 ETO20814.1 - 7.4e-05 22.1 3.2 0.0002 20.7 2.2 1.8 1 1 0 1 1 1 1 TFIIS helical bundle-like domain A_deaminase PF00962.17 ETO20815.1 - 1.3e-31 109.7 2.8 1.9e-31 109.2 1.9 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase zf-RanBP PF00641.13 ETO20817.1 - 7.7e-15 53.6 14.5 7.9e-08 31.2 2.1 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.2 ETO20817.1 - 0.0029 17.3 6.7 0.54 10.1 0.2 2.3 2 0 0 2 2 2 2 Double zinc ribbon DUF4650 PF15509.1 ETO20817.1 - 0.011 14.7 13.0 0.015 14.2 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4650) zf-Sec23_Sec24 PF04810.10 ETO20817.1 - 0.047 13.2 0.8 0.047 13.2 0.5 3.4 2 2 2 4 4 4 0 Sec23/Sec24 zinc finger CAF-1_p150 PF11600.3 ETO20817.1 - 0.093 12.0 24.1 0.14 11.4 16.7 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal zf-MIZ PF02891.15 ETO20817.1 - 0.13 11.7 8.2 0.95 9.0 0.3 2.8 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger AAA_23 PF13476.1 ETO20817.1 - 0.14 12.4 8.1 0.17 12.1 5.6 1.1 1 0 0 1 1 1 0 AAA domain GCC2_GCC3 PF07699.8 ETO20817.1 - 0.92 9.1 9.9 0.072 12.6 1.9 2.3 2 0 0 2 2 2 0 GCC2 and GCC3 Rubredoxin PF00301.15 ETO20817.1 - 1.1 9.2 8.9 7.6 6.4 0.1 3.2 2 1 0 2 2 2 0 Rubredoxin SprA-related PF12118.3 ETO20817.1 - 1.6 7.9 19.3 2.1 7.5 13.4 1.1 1 0 0 1 1 1 0 SprA-related family APG6 PF04111.7 ETO20817.1 - 6.7 5.6 14.5 9.1 5.2 10.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 RAP1 PF07218.6 ETO20817.1 - 8.5 4.3 11.4 10 4.0 7.9 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ras PF00071.17 ETO20818.1 - 2.5e-49 166.7 0.2 3.4e-49 166.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO20818.1 - 4.3e-13 49.8 0.0 6.9e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO20818.1 - 6.2e-12 45.0 0.0 8.1e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETO20818.1 - 0.00019 20.6 0.1 0.00028 20.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 ETO20818.1 - 0.0031 17.4 0.0 0.0042 17.0 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 ETO20818.1 - 0.006 16.0 0.0 0.012 15.0 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 ETO20818.1 - 0.11 11.6 0.1 0.36 10.0 0.0 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Vfa1 PF08432.5 ETO20819.1 - 5 7.1 15.6 6.8 6.6 2.9 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Tom37_C PF11801.3 ETO20819.1 - 6.9 6.5 9.3 3.1 7.6 1.5 2.5 2 0 0 2 2 2 0 Tom37 C-terminal domain PRP38 PF03371.10 ETO20820.1 - 7.6e-36 123.3 0.0 4.2e-30 104.6 0.1 2.2 2 0 0 2 2 2 2 PRP38 family NKWYS PF10364.4 ETO20820.1 - 0.034 13.8 2.8 2.5 7.8 0.1 2.4 2 0 0 2 2 2 0 Putative capsular polysaccharide synthesis protein PEPCK_ATP PF01293.15 ETO20822.1 - 1.8e-159 531.1 0.0 2e-159 531.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.1 ETO20822.1 - 0.0069 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 ETO20822.1 - 0.12 11.9 0.4 0.25 10.9 0.3 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain BatD PF13584.1 ETO20823.1 - 0.032 12.8 6.4 0.065 11.8 1.8 2.4 2 1 0 2 2 2 0 Oxygen tolerance DUF912 PF06024.7 ETO20823.1 - 0.2 11.7 7.6 0.16 12.0 1.5 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) EphA2_TM PF14575.1 ETO20823.1 - 3.6 8.0 0.0 3.6 8.0 0.0 3.2 3 1 1 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain GGDEF PF00990.16 ETO20824.1 - 0.0016 18.0 0.0 0.0053 16.3 0.0 1.8 1 1 1 2 2 2 1 GGDEF domain DUF4386 PF14329.1 ETO20826.1 - 0.074 12.5 0.1 0.095 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) AMP-binding PF00501.23 ETO20828.1 - 2.8e-41 141.2 0.0 4.1e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETO20828.1 - 0.0062 17.4 0.3 2.8 8.9 0.0 2.6 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Proteasome PF00227.21 ETO20829.1 - 4.7e-13 48.8 0.1 6.2e-13 48.4 0.1 1.3 1 1 0 1 1 1 1 Proteasome subunit Prp19 PF08606.6 ETO20830.1 - 1.3 8.7 8.8 4.8 6.9 0.2 2.9 2 1 0 2 2 2 0 Prp19/Pso4-like EF-hand_1 PF00036.27 ETO20831.1 - 1.3e-11 42.8 2.6 7.7e-06 24.8 0.8 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 ETO20831.1 - 7.8e-11 41.4 2.1 0.00026 20.5 0.8 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.1 ETO20831.1 - 2.3e-09 37.2 3.4 0.00051 20.1 0.3 2.1 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO20831.1 - 1.2e-08 34.0 1.4 0.0035 17.0 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 ETO20831.1 - 3e-06 26.3 2.2 0.05 12.9 0.5 2.4 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.4 ETO20831.1 - 6.4e-05 22.9 0.2 9.8e-05 22.3 0.2 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 ETO20831.1 - 0.00025 20.8 0.7 0.4 10.6 0.1 2.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_4 PF12763.2 ETO20831.1 - 0.0068 16.1 1.1 0.18 11.5 0.2 2.3 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand Pollen_allerg_2 PF01620.11 ETO20831.1 - 0.034 14.4 0.1 0.05 13.9 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) DUF4167 PF13763.1 ETO20831.1 - 0.14 12.1 1.2 18 5.4 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4167) DUF1282 PF06930.7 ETO20834.1 - 0.61 9.7 11.9 3.9 7.1 5.9 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1282) DUF3671 PF12420.3 ETO20834.1 - 0.79 9.7 17.6 0.24 11.3 6.7 2.8 1 1 2 3 3 3 0 Protein of unknown function FtsX PF02687.16 ETO20834.1 - 8.6 6.1 15.9 28 4.5 8.1 3.1 2 1 0 2 2 2 0 FtsX-like permease family Abhydrolase_5 PF12695.2 ETO20835.1 - 1.1e-24 86.9 0.0 1.4e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETO20835.1 - 4e-13 49.7 0.0 1.1e-05 25.4 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETO20835.1 - 1.1e-08 34.5 0.0 6.3e-08 32.1 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 ETO20835.1 - 1.5e-07 31.0 0.2 2.4e-05 23.9 0.1 3.0 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 ETO20835.1 - 5.8e-07 29.3 0.0 9.6e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF818 PF05677.7 ETO20835.1 - 1e-05 24.4 0.0 1.7e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Hydrolase_4 PF12146.3 ETO20835.1 - 5.2e-05 23.0 0.0 0.00013 21.7 0.0 1.7 2 0 0 2 2 2 1 Putative lysophospholipase DUF1749 PF08538.5 ETO20835.1 - 0.00014 20.8 0.0 0.0002 20.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) FSH1 PF03959.8 ETO20835.1 - 0.00023 20.6 0.1 0.0026 17.2 0.0 2.5 1 1 2 3 3 3 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.15 ETO20835.1 - 0.00036 20.1 0.0 0.31 10.5 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold LIP PF03583.9 ETO20835.1 - 0.002 17.3 0.0 0.013 14.6 0.0 2.0 2 0 0 2 2 2 1 Secretory lipase DLH PF01738.13 ETO20835.1 - 0.01 15.1 0.1 0.041 13.1 0.0 2.0 2 1 0 2 2 2 0 Dienelactone hydrolase family BAAT_C PF08840.6 ETO20835.1 - 0.018 14.7 0.0 7 6.2 0.0 2.3 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal KH_dom-like PF14714.1 ETO20835.1 - 0.09 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal PMC2NT PF08066.7 ETO20835.1 - 0.11 12.7 1.1 0.23 11.7 0.8 1.5 1 0 0 1 1 1 0 PMC2NT (NUC016) domain Qn_am_d_aII PF14930.1 ETO20835.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II Daxx PF03344.10 ETO20836.1 - 0.49 8.8 33.2 0.86 8.0 23.0 1.4 1 1 0 1 1 1 0 Daxx Family MIP-T3 PF10243.4 ETO20837.1 - 5.9 5.2 28.0 7.7 4.8 19.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1675 PF07897.6 ETO20837.1 - 6.7 6.4 23.4 9.6 5.9 16.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) ADK PF00406.17 ETO20838.1 - 3.4e-29 101.6 0.3 9.4e-29 100.2 0.2 1.6 1 1 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 ETO20838.1 - 7.3e-14 51.1 0.3 2.3e-13 49.5 0.0 1.9 2 0 0 2 2 2 1 Adenylate kinase, active site lid DUF1423 PF07227.6 ETO20839.1 - 0.37 9.3 4.2 0.62 8.6 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) SURF2 PF05477.6 ETO20840.1 - 0.02 14.0 5.0 0.034 13.2 3.5 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Acyl-ACP_TE PF01643.12 ETO20841.1 - 0.036 13.0 0.1 0.057 12.3 0.0 1.3 1 0 0 1 1 1 0 Acyl-ACP thioesterase Helicase_C PF00271.26 ETO20842.1 - 0.052 13.4 0.1 0.13 12.0 0.1 1.7 1 0 0 1 1 1 0 Helicase conserved C-terminal domain DEAD PF00270.24 ETO20843.1 - 6.2e-11 42.0 0.2 8.9e-09 35.0 0.1 3.8 2 1 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 ETO20843.1 - 0.0032 17.3 1.7 0.019 14.7 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 ETO20843.1 - 0.0042 17.2 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Helicase_C PF00271.26 ETO20843.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain AAA PF00004.24 ETO20843.1 - 0.026 14.7 0.2 0.14 12.3 0.2 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) YopH_N PF09013.5 ETO20843.1 - 0.056 13.1 0.0 0.19 11.3 0.0 1.9 1 0 0 1 1 1 0 YopH, N-terminal BTB PF00651.26 ETO20844.1 - 4.7e-14 52.3 0.3 1.2e-13 51.0 0.2 1.7 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 ETO20844.1 - 0.003 17.3 0.7 0.0096 15.7 0.1 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch Neil1-DNA_bind PF09292.5 ETO20844.1 - 0.047 13.4 0.4 0.097 12.4 0.3 1.5 1 0 0 1 1 1 0 Endonuclease VIII-like 1, DNA bind PIG-P PF08510.7 ETO20845.1 - 0.006 16.2 0.0 0.0096 15.5 0.0 1.3 1 0 0 1 1 1 1 PIG-P DUF810 PF05664.6 ETO20845.1 - 0.084 11.1 0.0 0.088 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF810) UcrQ PF02939.11 ETO20845.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 UcrQ family APC8 PF04049.8 ETO20846.1 - 1.1e-13 51.1 0.3 1.5e-13 50.7 0.2 1.2 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 7tm_1 PF00001.16 ETO20846.1 - 0.0017 17.5 8.5 0.0025 16.9 5.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3816 PF12822.2 ETO20846.1 - 0.016 15.1 6.6 0.021 14.6 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) TraL PF07178.6 ETO20846.1 - 0.49 10.4 4.8 0.24 11.4 0.3 2.1 2 0 0 2 2 2 0 TraL protein PRA1 PF03208.14 ETO20846.1 - 1.2 8.4 9.9 1.8 7.8 6.9 1.2 1 0 0 1 1 1 0 PRA1 family protein Peptidase_M42 PF05343.9 ETO20847.1 - 0.018 13.8 0.0 0.019 13.7 0.0 1.1 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase Actin PF00022.14 ETO20847.1 - 0.037 12.4 0.0 0.042 12.2 0.0 1.1 1 0 0 1 1 1 0 Actin Tcf25 PF04910.9 ETO20848.1 - 1e-76 258.2 3.9 1.6e-76 257.6 2.7 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 GF_recep_IV PF14843.1 ETO20848.1 - 0.057 13.0 2.8 0.11 12.1 1.9 1.4 1 0 0 1 1 1 0 Growth factor receptor domain IV Laminin_II PF06009.7 ETO20849.1 - 0.0016 18.2 3.2 0.0025 17.5 2.2 1.3 1 0 0 1 1 1 1 Laminin Domain II IncA PF04156.9 ETO20849.1 - 0.01 15.4 2.2 0.014 14.9 1.6 1.2 1 0 0 1 1 1 0 IncA protein DUF1202 PF06717.6 ETO20849.1 - 0.081 12.1 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) Atg14 PF10186.4 ETO20849.1 - 0.38 9.6 7.1 0.6 9.0 4.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Med4 PF10018.4 ETO20849.1 - 1.1 8.6 9.3 0.075 12.4 3.1 1.5 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Utp14 PF04615.8 ETO20850.1 - 0.33 9.0 85.0 0.41 8.7 58.9 1.1 1 0 0 1 1 1 0 Utp14 protein Pkinase PF00069.20 ETO20851.1 - 3.7e-55 186.8 0.4 5.9e-54 182.9 0.0 2.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO20851.1 - 3e-27 95.3 0.0 9e-27 93.7 0.0 1.9 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.24 ETO20851.1 - 6.3e-18 64.3 0.0 1.3e-11 44.1 0.0 3.6 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Ion_trans PF00520.26 ETO20852.1 - 1.3e-15 57.2 5.0 1.9e-15 56.6 3.5 1.3 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.7 ETO20852.1 - 0.00036 19.0 0.2 0.00048 18.6 0.2 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 ETO20853.1 - 1e-39 135.8 17.7 2.3e-29 102.0 6.5 3.4 3 2 1 4 4 4 2 Ion transport protein PKD_channel PF08016.7 ETO20853.1 - 3.7e-05 22.3 2.2 3.7e-05 22.3 1.5 3.9 3 2 1 4 4 4 3 Polycystin cation channel Ion_trans PF00520.26 ETO20854.1 - 0.11 11.7 0.3 0.11 11.7 0.2 1.6 2 0 0 2 2 2 0 Ion transport protein ATP-synt_8 PF00895.15 ETO20854.1 - 0.16 12.1 0.4 0.27 11.4 0.3 1.4 1 0 0 1 1 1 0 ATP synthase protein 8 ETRAMP PF09716.5 ETO20854.1 - 0.46 10.4 2.1 11 6.0 0.1 2.3 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Ion_trans PF00520.26 ETO20855.1 - 1.3e-25 89.8 25.3 4.3e-25 88.1 17.5 1.8 1 1 0 1 1 1 1 Ion transport protein Rb_C PF08934.5 ETO20855.1 - 1.1 8.8 3.7 1.9 8.0 2.6 1.3 1 0 0 1 1 1 0 Rb C-terminal domain Senescence_reg PF04520.8 ETO20857.1 - 0.086 13.3 0.4 0.086 13.3 0.2 2.9 1 1 2 3 3 3 0 Senescence regulator Guanylate_cyc PF00211.15 ETO20859.1 - 1.3e-16 60.4 0.0 1.1e-11 44.3 0.0 3.2 2 1 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Kinesin PF00225.18 ETO20860.1 - 9.2e-13 47.5 4.0 1.6e-11 43.5 2.8 2.1 1 1 0 1 1 1 1 Kinesin motor domain IL6 PF00489.12 ETO20860.1 - 0.093 12.3 3.1 0.063 12.8 0.6 1.9 2 1 0 2 2 2 0 Interleukin-6/G-CSF/MGF family BAF1_ABF1 PF04684.8 ETO20861.1 - 0.031 13.1 16.3 0.071 11.9 11.3 1.6 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor ORF6C PF10552.4 ETO20862.1 - 0.013 15.2 0.1 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 ORF6C domain zf-C3HC4_3 PF13920.1 ETO20862.1 - 0.062 12.9 0.5 0.1 12.3 0.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO20862.1 - 0.084 12.5 1.3 0.16 11.6 0.5 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Terminase_2 PF03592.11 ETO20862.1 - 0.084 13.1 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 Terminase small subunit zf-RING_5 PF14634.1 ETO20862.1 - 0.11 12.2 0.4 0.2 11.4 0.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Paramyxo_PNT PF13825.1 ETO20862.1 - 0.13 11.4 2.5 0.17 11.0 1.8 1.2 1 0 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus zf-C3HC4_2 PF13923.1 ETO20862.1 - 0.16 11.9 0.8 0.36 10.9 0.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF846 PF05832.7 ETO20863.1 - 1.4e-42 144.7 15.0 1.4e-42 144.7 10.4 2.1 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF846) PROCN PF08083.6 ETO20865.1 - 1.7e-220 731.6 7.0 2.9e-220 730.8 4.8 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 ETO20865.1 - 8.6e-125 414.6 0.5 1.5e-124 413.8 0.4 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 ETO20865.1 - 6.7e-94 311.5 1.5 1.6e-93 310.3 1.1 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 U5_2-snRNA_bdg PF10597.4 ETO20865.1 - 3.4e-67 224.2 0.1 6.7e-67 223.2 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 ETO20865.1 - 1.6e-41 140.9 0.2 4.1e-41 139.5 0.1 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.4 ETO20865.1 - 5.8e-41 138.2 0.1 1.7e-40 136.7 0.1 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.16 ETO20865.1 - 0.00012 21.7 0.0 0.00051 19.7 0.0 2.1 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Ni_hydr_CYTB PF01292.15 ETO20867.1 - 0.044 13.1 0.1 0.053 12.9 0.1 1.3 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 LSM PF01423.17 ETO20868.1 - 2.8e-11 42.7 1.0 4.7e-11 42.0 0.1 1.8 2 0 0 2 2 2 1 LSM domain Uteroglobin PF01099.12 ETO20869.1 - 0.73 9.6 6.1 0.21 11.4 1.6 2.1 2 0 0 2 2 2 0 Uteroglobin family RNA_pol_Rpb1_5 PF04998.12 ETO20869.1 - 4.8 6.3 5.7 7 5.8 4.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 TPR_11 PF13414.1 ETO20870.1 - 7e-08 31.9 26.2 0.23 11.1 0.2 8.8 6 2 1 7 7 7 4 TPR repeat TPR_14 PF13428.1 ETO20870.1 - 2.9e-06 27.4 8.3 11 6.9 0.1 9.6 11 1 0 11 11 9 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO20870.1 - 3.9e-06 26.6 27.2 0.088 12.7 0.2 8.6 7 1 1 8 8 8 1 Tetratricopeptide repeat PPR PF01535.15 ETO20870.1 - 0.00019 21.1 5.1 3.1 7.9 0.0 6.0 6 0 0 6 6 6 2 PPR repeat Clathrin PF00637.15 ETO20870.1 - 0.00076 19.1 31.2 0.42 10.2 0.3 8.0 4 2 2 7 7 7 3 Region in Clathrin and VPS PPR_2 PF13041.1 ETO20870.1 - 0.00091 19.1 0.1 0.52 10.3 0.0 3.9 4 0 0 4 4 4 1 PPR repeat family TPR_2 PF07719.12 ETO20870.1 - 0.0046 16.7 39.5 1.4 9.0 0.3 11.3 10 2 2 12 12 12 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO20870.1 - 0.0074 16.6 20.4 4.5 7.6 0.1 9.0 8 1 1 9 9 9 1 Tetratricopeptide repeat PPR_3 PF13812.1 ETO20870.1 - 0.049 13.9 0.3 17 6.0 0.0 4.2 4 0 0 4 4 3 0 Pentatricopeptide repeat domain TPR_7 PF13176.1 ETO20870.1 - 0.056 13.2 22.1 24 5.0 0.1 9.7 8 3 0 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETO20870.1 - 0.13 12.0 38.0 0.62 9.9 0.1 10.1 10 1 0 10 10 9 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETO20870.1 - 3 7.5 41.9 11 5.8 0.0 11.2 11 1 1 12 12 12 0 Tetratricopeptide repeat Selenoprotein_S PF06936.6 ETO20870.1 - 5 6.6 7.2 0.21 11.1 0.1 2.2 3 0 0 3 3 3 0 Selenoprotein S (SelS) Heme_oxygenase PF01126.15 ETO20871.1 - 0.041 13.4 0.1 0.052 13.1 0.1 1.2 1 0 0 1 1 1 0 Heme oxygenase FH2 PF02181.18 ETO20872.1 - 8.4e-09 34.7 3.6 8.4e-09 34.7 2.5 2.6 2 0 0 2 2 2 1 Formin Homology 2 Domain PH PF00169.24 ETO20872.1 - 0.00066 19.8 0.1 0.0034 17.5 0.0 2.3 1 0 0 1 1 1 1 PH domain FlaC_arch PF05377.6 ETO20872.1 - 0.013 15.3 2.0 0.084 12.7 1.4 2.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) CAP_GLY PF01302.20 ETO20873.1 - 3.5e-06 26.6 1.1 6.5e-06 25.7 0.8 1.5 1 0 0 1 1 1 1 CAP-Gly domain NARP1 PF12569.3 ETO20873.1 - 0.27 9.9 4.7 0.4 9.3 3.3 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Spt5_N PF11942.3 ETO20875.1 - 4.8 7.8 20.1 4.5 7.9 9.9 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Macoilin PF09726.4 ETO20875.1 - 5.4 5.1 14.1 8.4 4.5 9.8 1.3 1 0 0 1 1 1 0 Transmembrane protein MCM PF00493.18 ETO20877.1 - 5.4e-116 387.0 0.1 1.6e-105 352.5 0.0 2.3 2 0 0 2 2 2 2 MCM2/3/5 family Mg_chelatase PF01078.16 ETO20877.1 - 9.7e-10 37.9 0.3 9.9e-07 28.1 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 ETO20877.1 - 1.9e-09 37.3 0.0 4.2e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 ETO20877.1 - 1.7e-06 27.6 0.0 4.9e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MCM_N PF14551.1 ETO20877.1 - 3.5e-06 27.5 2.1 3.5e-06 27.5 1.5 2.6 2 1 0 2 2 2 1 MCM N-terminal domain AAA PF00004.24 ETO20877.1 - 0.00045 20.4 0.2 0.0021 18.2 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 ETO20877.1 - 0.00058 19.3 0.0 0.18 11.2 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain RuvB_N PF05496.7 ETO20877.1 - 0.0077 15.3 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activ_2 PF14532.1 ETO20877.1 - 0.024 14.6 0.1 0.13 12.2 0.0 2.3 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_22 PF13401.1 ETO20877.1 - 0.049 13.7 0.4 0.28 11.3 0.1 2.4 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 ETO20877.1 - 0.058 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.1 ETO20877.1 - 0.1 12.5 0.1 2.6 8.0 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Ras PF00071.17 ETO20878.1 - 1.2e-24 86.5 0.2 1.6e-24 86.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO20878.1 - 0.014 15.8 0.1 0.022 15.2 0.0 1.3 1 0 0 1 1 1 0 Miro-like protein Arf PF00025.16 ETO20878.1 - 0.016 14.4 0.0 0.021 14.0 0.0 1.1 1 0 0 1 1 1 0 ADP-ribosylation factor family DUF3527 PF12043.3 ETO20879.1 - 0.048 13.1 0.9 0.051 13.1 0.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) RhoGAP PF00620.22 ETO20880.1 - 9.1e-19 67.5 0.0 4.2e-15 55.6 0.0 2.3 2 0 0 2 2 2 2 RhoGAP domain PBD PF00786.23 ETO20880.1 - 0.017 15.5 0.1 0.079 13.3 0.0 2.2 1 1 1 2 2 2 0 P21-Rho-binding domain DBINO PF13892.1 ETO20882.1 - 0.019 15.0 2.6 0.025 14.6 1.8 1.1 1 0 0 1 1 1 0 DNA-binding domain DUF3106 PF11304.3 ETO20882.1 - 0.083 13.3 2.6 0.11 12.8 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) DUF4570 PF15134.1 ETO20882.1 - 0.09 12.6 3.0 0.12 12.1 1.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4570) DUF972 PF06156.8 ETO20882.1 - 0.12 12.7 2.8 0.15 12.4 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF3439 PF11921.3 ETO20883.1 - 0.015 15.0 2.3 0.03 14.0 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) FtsX PF02687.16 ETO20883.1 - 0.16 11.7 7.4 0.12 12.1 1.4 2.2 2 0 0 2 2 2 0 FtsX-like permease family TRAP_alpha PF03896.11 ETO20883.1 - 0.97 8.3 6.7 0.48 9.3 2.2 1.9 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit FAM176 PF14851.1 ETO20883.1 - 3.6 7.2 6.2 6.2 6.4 2.1 2.2 2 0 0 2 2 2 0 FAM176 family P5-ATPase PF12409.3 ETO20883.1 - 8.6 6.2 8.3 1 9.2 0.9 2.5 2 0 0 2 2 2 0 P5-type ATPase cation transporter DUF1049 PF06305.6 ETO20883.1 - 9 5.8 6.7 6.1 6.4 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) SDA1 PF05285.7 ETO20884.1 - 0.5 9.6 28.9 0.71 9.0 20.0 1.2 1 0 0 1 1 1 0 SDA1 DUF1180 PF06679.7 ETO20885.1 - 2.7 7.8 7.8 0.61 9.9 1.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1180) MOR2-PAG1_C PF14225.1 ETO20886.1 - 2.8e-12 46.9 0.5 4.8e-10 39.6 0.0 2.9 3 0 0 3 3 3 2 Cell morphogenesis C-terminal CENP-B_dimeris PF09026.5 ETO20887.1 - 0.011 15.9 1.2 0.022 14.9 0.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TRAP_alpha PF03896.11 ETO20887.1 - 0.076 12.0 0.4 0.094 11.6 0.3 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NlpE PF04170.7 ETO20890.1 - 0.058 13.7 0.7 0.11 12.9 0.1 1.7 1 1 1 2 2 2 0 NlpE N-terminal domain AAA_34 PF13872.1 ETO20890.1 - 0.092 11.4 0.6 0.11 11.1 0.4 1.1 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 Thioredoxin_4 PF13462.1 ETO20890.1 - 0.33 10.9 2.8 0.51 10.3 1.9 1.3 1 0 0 1 1 1 0 Thioredoxin ERp29 PF07749.7 ETO20890.1 - 0.36 11.5 5.5 0.63 10.7 3.8 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain Duffy_binding PF05424.6 ETO20892.1 - 0.092 12.5 3.4 0.11 12.2 2.4 1.2 1 0 0 1 1 1 0 Duffy binding domain FlgN PF05130.7 ETO20892.1 - 0.4 10.9 3.3 0.69 10.1 2.0 1.6 1 1 0 1 1 1 0 FlgN protein NYD-SP28 PF14772.1 ETO20892.1 - 3.2 7.9 8.8 12 6.0 6.1 2.0 1 1 0 1 1 1 0 Sperm tail FAM196 PF15265.1 ETO20893.1 - 0.62 9.2 5.2 1.8 7.6 0.4 2.0 2 0 0 2 2 2 0 FAM196 family zf-CCHC PF00098.18 ETO20895.1 - 1.9e-07 30.6 24.1 0.0035 17.2 3.5 3.5 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.1 ETO20895.1 - 0.00041 20.0 31.7 0.018 14.7 3.4 3.3 2 1 1 3 3 3 2 Zinc knuckle ARS2 PF04959.8 ETO20895.1 - 0.15 12.1 1.7 0.2 11.8 0.7 1.6 1 1 1 2 2 2 0 Arsenite-resistance protein 2 zf-CCHC_4 PF14392.1 ETO20895.1 - 2.3 7.9 20.3 0.47 10.1 0.8 3.3 2 1 1 3 3 3 0 Zinc knuckle DcpS_C PF11969.3 ETO20896.1 - 2e-06 28.0 0.9 5e-06 26.7 0.6 1.7 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding FANCI_HD1 PF14679.1 ETO20896.1 - 0.09 12.5 0.3 5.4 6.8 0.1 2.7 2 1 0 2 2 2 0 FANCI helical domain 1 TPR_12 PF13424.1 ETO20897.1 - 3.7e-104 340.7 36.8 4.9e-21 74.4 1.2 6.4 2 2 5 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.1 ETO20897.1 - 3.6e-54 179.2 0.0 3.5e-07 29.9 0.0 9.3 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_11 PF13414.1 ETO20897.1 - 1.8e-51 171.6 53.7 6e-16 57.8 2.1 6.6 4 1 3 7 7 7 7 TPR repeat TPR_1 PF00515.23 ETO20897.1 - 6e-51 168.0 48.6 4e-09 35.7 0.1 8.8 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_7 PF13176.1 ETO20897.1 - 5.2e-42 138.3 16.2 4e-05 23.1 0.1 9.3 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.12 ETO20897.1 - 3.1e-41 135.9 39.1 4.8e-06 26.0 0.4 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_8 PF13181.1 ETO20897.1 - 1e-32 109.4 52.4 0.00016 21.2 0.4 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_17 PF13431.1 ETO20897.1 - 1.3e-19 68.6 21.6 0.004 17.2 0.0 9.1 8 1 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 ETO20897.1 - 2.4e-15 56.7 0.1 0.00065 20.3 0.0 6.2 2 1 5 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO20897.1 - 3.3e-14 52.2 8.7 1.3 9.6 0.0 8.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO20897.1 - 2.9e-13 49.1 0.0 0.28 11.9 0.0 8.0 8 0 0 8 8 8 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO20897.1 - 7.1e-11 42.0 22.9 0.00048 20.2 1.9 5.5 2 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 ETO20897.1 - 1.2e-10 40.5 13.7 0.1 12.6 0.2 6.4 6 0 0 6 6 5 4 PPR repeat MIT PF04212.13 ETO20897.1 - 7.2e-08 32.2 21.6 0.57 10.1 0.1 8.0 8 0 0 8 8 8 3 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 ETO20897.1 - 6.3e-07 29.0 26.9 0.0078 15.9 0.1 7.1 8 0 0 8 8 8 3 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO20897.1 - 9.1e-07 28.0 0.3 0.88 8.8 0.0 6.1 6 0 0 6 6 6 1 SHNi-TPR TPR_19 PF14559.1 ETO20897.1 - 9.3e-07 29.0 2.5 0.0084 16.4 0.1 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat DUF2225 PF09986.4 ETO20897.1 - 3.3e-05 23.4 25.0 0.12 11.7 1.4 5.4 1 1 3 5 5 5 4 Uncharacterized protein conserved in bacteria (DUF2225) DUF627 PF04781.7 ETO20897.1 - 0.0046 16.5 4.7 0.98 9.0 0.0 5.0 4 2 1 5 5 5 1 Protein of unknown function (DUF627) TPR_5 PF12688.2 ETO20897.1 - 0.011 15.7 1.0 7.4 6.6 0.0 4.4 4 1 2 6 6 4 0 Tetratrico peptide repeat DUF3856 PF12968.2 ETO20897.1 - 0.03 14.1 1.8 19 5.0 0.1 3.8 2 1 3 5 5 5 0 Domain of Unknown Function (DUF3856) PPR_2 PF13041.1 ETO20897.1 - 0.13 12.2 13.4 15 5.6 0.0 5.8 6 0 0 6 6 5 0 PPR repeat family Sel1 PF08238.7 ETO20897.1 - 2.1 9.0 27.9 16 6.2 0.2 7.7 8 0 0 8 8 8 0 Sel1 repeat Pkinase PF00069.20 ETO20898.1 - 3.8e-20 72.1 0.6 7.6e-20 71.1 0.4 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO20898.1 - 4.8e-16 58.5 0.1 4.8e-16 58.5 0.1 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Usp PF00582.21 ETO20899.1 - 1.3e-21 77.2 0.4 1.2e-15 57.8 0.0 2.3 2 0 0 2 2 2 2 Universal stress protein family PUF PF00806.14 ETO20900.1 - 0.02 14.3 2.1 0.59 9.7 0.9 2.7 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat Albumin_I PF08027.6 ETO20900.1 - 0.71 9.6 7.8 11 5.7 0.0 2.6 2 0 0 2 2 2 0 Albumin I NUC202 PF08166.7 ETO20901.1 - 0.24 11.2 1.3 2.3 8.1 0.1 2.5 2 1 1 3 3 3 0 NUC202 domain ATP_bind_1 PF03029.12 ETO20903.1 - 9.7e-44 149.6 8.9 3.4e-38 131.5 0.4 3.5 3 1 0 3 3 2 2 Conserved hypothetical ATP binding protein TPR_11 PF13414.1 ETO20903.1 - 5.8e-21 73.9 6.5 9.3e-12 44.4 1.6 3.1 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 ETO20903.1 - 3.9e-11 42.0 10.1 0.0033 16.9 0.4 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO20903.1 - 2e-08 33.5 9.3 0.0081 16.0 0.2 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO20903.1 - 1.6e-06 28.6 0.1 0.00015 22.3 0.0 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO20903.1 - 1.2e-05 25.1 6.9 0.063 13.4 0.1 4.4 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO20903.1 - 7.2e-05 22.6 3.6 0.051 13.5 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO20903.1 - 0.00029 20.9 6.4 0.044 13.9 4.4 2.7 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO20903.1 - 0.00067 19.9 2.3 0.0017 18.6 0.1 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO20903.1 - 0.00085 19.7 0.3 0.22 12.2 0.0 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat AAA_17 PF13207.1 ETO20903.1 - 0.0019 19.0 0.0 0.0067 17.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain SHNi-TPR PF10516.4 ETO20903.1 - 0.0024 17.0 0.3 0.91 8.8 0.0 2.9 3 0 0 3 3 3 1 SHNi-TPR AAA_10 PF12846.2 ETO20903.1 - 0.0038 16.7 0.0 0.0071 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_11 PF13086.1 ETO20903.1 - 0.02 14.4 4.3 0.21 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 ETO20903.1 - 0.03 14.0 0.0 0.089 12.5 0.0 1.7 2 0 0 2 2 1 0 Part of AAA domain RNA_helicase PF00910.17 ETO20903.1 - 0.031 14.4 0.1 0.13 12.4 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 ETO20903.1 - 0.034 14.3 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 ETO20903.1 - 0.035 14.0 0.2 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 ETO20903.1 - 0.058 13.0 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 ETO20903.1 - 0.093 12.8 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 ETO20903.1 - 0.11 12.8 1.4 0.61 10.3 0.0 2.8 3 0 0 3 3 2 0 AAA domain TPR_8 PF13181.1 ETO20903.1 - 0.14 11.9 10.2 4.1 7.4 0.1 5.3 5 1 0 5 5 3 0 Tetratricopeptide repeat DUF87 PF01935.12 ETO20903.1 - 0.15 11.8 2.9 0.81 9.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 TPR_7 PF13176.1 ETO20903.1 - 0.18 11.6 1.7 1.4 8.9 0.2 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 ETO20903.1 - 3.4 7.9 8.3 13 6.0 0.3 2.3 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation TA0956 PF11513.3 ETO20904.1 - 0.11 12.5 0.2 14 5.7 0.1 2.2 2 0 0 2 2 2 0 Thermoplasma acidophilum protein TA0956 Med12-LCEWAV PF12145.3 ETO20904.1 - 0.28 9.5 3.9 0.32 9.4 2.7 1.0 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain Ank PF00023.25 ETO20905.1 - 3e-18 64.6 3.3 1.7e-08 33.8 0.3 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 ETO20905.1 - 3.2e-18 65.8 0.3 5.3e-18 65.1 0.2 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO20905.1 - 6e-18 64.8 1.1 5.3e-12 45.8 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO20905.1 - 9.4e-15 53.2 1.0 5.3e-07 29.2 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 ETO20905.1 - 1.4e-12 47.3 0.9 3.1e-06 27.2 0.2 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Guanylate_kin PF00625.16 ETO20906.1 - 1.4e-10 40.9 0.7 3.3e-07 29.9 0.1 2.1 2 0 0 2 2 2 2 Guanylate kinase DUF258 PF03193.11 ETO20906.1 - 5.5e-06 25.6 0.1 0.00044 19.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 ETO20906.1 - 0.00019 21.7 0.1 0.00051 20.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ETO20906.1 - 0.0035 17.4 0.1 0.18 11.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 ETO20906.1 - 0.0071 16.5 0.4 0.016 15.3 0.2 1.7 1 1 0 1 1 1 1 RNA helicase Septin PF00735.13 ETO20906.1 - 0.0072 15.3 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Septin AAA_17 PF13207.1 ETO20906.1 - 0.0081 16.9 0.4 0.02 15.7 0.3 1.8 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 ETO20906.1 - 0.048 13.2 0.6 0.091 12.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 ETO20906.1 - 0.052 13.4 0.5 0.11 12.4 0.3 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 ETO20906.1 - 0.052 13.8 0.9 0.25 11.6 0.6 2.1 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 ETO20906.1 - 0.12 12.2 0.5 0.87 9.4 0.3 2.1 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 ETO20906.1 - 1.9 8.7 6.3 3 8.1 4.3 1.4 1 1 0 1 1 1 0 AAA domain SOG2 PF10428.4 ETO20908.1 - 0.17 10.5 13.0 0.22 10.1 9.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Neur_chan_memb PF02932.11 ETO20908.1 - 2.9 7.7 7.7 3.7 7.3 1.3 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region AAA PF00004.24 ETO20910.1 - 2e-18 66.8 0.0 2.9e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 ETO20910.1 - 5e-07 29.5 1.1 1.5e-06 28.0 0.2 2.1 2 1 0 2 2 2 1 Vps4 C terminal oligomerisation domain DUF1313 PF07011.6 ETO20913.1 - 0.053 13.2 0.6 2.2 7.9 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1313) Baculo_PEP_C PF04513.7 ETO20913.1 - 0.081 12.7 2.0 0.15 11.8 1.4 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF202 PF02656.10 ETO20914.1 - 7.3e-08 32.5 2.0 1.8e-07 31.2 1.4 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF202) VTC PF09359.5 ETO20914.1 - 0.00056 19.0 0.0 0.00094 18.2 0.0 1.4 1 0 0 1 1 1 1 VTC domain Zip PF02535.17 ETO20915.1 - 0.029 13.3 0.2 0.029 13.3 0.1 2.2 1 1 0 2 2 2 0 ZIP Zinc transporter Tetraspannin PF00335.15 ETO20915.1 - 0.69 9.1 14.1 0.14 11.4 0.1 2.3 2 0 0 2 2 2 0 Tetraspanin family LMBR1 PF04791.11 ETO20915.1 - 5 5.5 9.5 0.044 12.3 0.6 1.8 2 0 0 2 2 2 0 LMBR1-like membrane protein Daxx PF03344.10 ETO20915.1 - 9.5 4.5 35.5 4.5 5.6 12.4 2.0 2 0 0 2 2 2 0 Daxx Family Utp12 PF04003.7 ETO20916.1 - 1.5e-08 34.4 0.7 2.5e-08 33.8 0.5 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family CDC45 PF02724.9 ETO20916.1 - 0.0024 15.9 8.0 0.0025 15.9 5.6 1.2 1 0 0 1 1 1 1 CDC45-like protein Trypan_PARP PF05887.6 ETO20916.1 - 0.015 15.1 16.7 0.02 14.6 11.5 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Vfa1 PF08432.5 ETO20916.1 - 0.17 11.8 26.2 0.018 15.1 14.6 1.9 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 ThiS PF02597.15 ETO20916.1 - 0.39 11.1 4.8 1.7 9.1 0.5 2.8 1 1 2 3 3 3 0 ThiS family DHHW PF14286.1 ETO20916.1 - 1.3 8.3 11.1 2 7.6 7.7 1.5 1 0 0 1 1 1 0 DHHW protein DDRGK PF09756.4 ETO20916.1 - 1.5 8.1 35.1 0.077 12.3 19.9 1.9 2 0 0 2 2 2 0 DDRGK domain HNOBA PF07701.9 ETO20916.1 - 1.6 7.8 11.2 3.7 6.7 7.5 1.8 1 1 0 1 1 1 0 Heme NO binding associated GET2 PF08690.5 ETO20916.1 - 2.5 7.2 8.3 1.5 7.9 4.6 1.5 2 0 0 2 2 2 0 GET complex subunit GET2 Pox_RNA_Pol_19 PF05320.7 ETO20916.1 - 3.4 7.3 16.1 0.64 9.7 8.8 1.6 2 0 0 2 2 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF4637 PF15470.1 ETO20916.1 - 4.8 6.7 16.8 1.9 8.0 9.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) Nucleoside_tran PF01733.13 ETO20916.1 - 7.6 5.5 5.9 13 4.8 4.1 1.4 1 0 0 1 1 1 0 Nucleoside transporter FAM60A PF15396.1 ETO20916.1 - 8.5 6.0 13.5 1.2 8.7 6.6 1.7 2 0 0 2 2 2 0 Protein Family FAM60A FAM178 PF14816.1 ETO20916.1 - 8.6 4.9 13.5 15 4.1 9.4 1.4 1 1 0 1 1 1 0 Family of unknown function, FAM178 RNA_pol_Rpb1_5 PF04998.12 ETO20916.1 - 9.2 5.4 12.7 3.9 6.6 7.1 1.7 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 5 Zip PF02535.17 ETO20916.1 - 9.8 5.0 8.9 14 4.5 6.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Guanylate_cyc PF00211.15 ETO20917.1 - 3e-15 56.0 0.1 2.6e-09 36.6 0.0 3.4 2 1 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain TPR_11 PF13414.1 ETO20918.1 - 0.019 14.5 0.0 0.048 13.3 0.0 1.7 1 0 0 1 1 1 0 TPR repeat Sigma70_ner PF04546.8 ETO20918.1 - 0.028 14.0 8.8 0.048 13.2 6.1 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region alpha-hel2 PF14456.1 ETO20918.1 - 0.13 11.0 0.5 0.18 10.5 0.3 1.3 1 0 0 1 1 1 0 Alpha-helical domain 2 TMEM237 PF15383.1 ETO20918.1 - 0.58 9.2 2.4 5 6.1 0.0 2.3 2 0 0 2 2 2 0 Transmembrane protein 237 CENP-B_dimeris PF09026.5 ETO20918.1 - 0.87 9.8 10.3 1.7 8.9 7.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 ETO20918.1 - 1.9 7.9 11.2 3.1 7.3 7.8 1.3 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 ETO20918.1 - 3.3 5.6 10.4 18 3.1 7.0 1.9 2 0 0 2 2 2 0 CDC45-like protein Jacalin PF01419.12 ETO20920.1 - 4.6e-10 39.4 0.1 1.5e-07 31.3 0.0 2.4 1 1 0 1 1 1 1 Jacalin-like lectin domain MMgT PF10270.4 ETO20921.1 - 0.018 15.4 1.4 0.03 14.7 1.0 1.5 1 0 0 1 1 1 0 Membrane magnesium transporter SKN1 PF03935.10 ETO20921.1 - 0.042 11.9 2.9 0.059 11.5 2.0 1.1 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) RSN1_TM PF13967.1 ETO20921.1 - 0.29 10.6 2.2 0.49 9.9 1.5 1.4 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport DUF912 PF06024.7 ETO20921.1 - 0.69 9.9 8.6 4.2 7.4 0.3 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2638 PF10937.3 ETO20921.1 - 2 9.4 6.1 4.2 8.4 4.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2638) G-alpha PF00503.15 ETO20922.1 - 3.2e-33 114.9 7.1 5.1e-33 114.3 4.9 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO20922.1 - 0.00026 20.2 0.4 0.00055 19.2 0.3 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family BCS1_N PF08740.6 ETO20922.1 - 0.034 13.7 0.2 0.08 12.5 0.1 1.6 1 1 1 2 2 2 0 BCS1 N terminal DUF1866 PF08952.6 ETO20922.1 - 0.18 11.3 1.1 6.1 6.3 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1866) RabGAP-TBC PF00566.13 ETO20923.1 - 5.6e-27 94.6 11.0 1.1e-13 51.1 3.1 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain SR-25 PF10500.4 ETO20923.1 - 0.056 12.9 9.4 0.075 12.4 6.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF508 PF04370.7 ETO20923.1 - 0.11 12.1 0.2 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) DUF755 PF05501.6 ETO20923.1 - 0.37 10.8 17.3 9 6.3 11.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF755) BLVR PF06375.6 ETO20923.1 - 1.1 9.0 3.7 1.7 8.4 2.6 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) DAGAT PF03982.8 ETO20924.1 - 5.9e-56 189.3 0.2 1.4e-55 188.0 0.0 1.6 1 1 1 2 2 2 1 Diacylglycerol acyltransferase PGAP1 PF07819.8 ETO20926.1 - 4.7e-35 121.1 0.8 1.3e-34 119.7 0.6 1.8 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 ETO20926.1 - 2.4e-06 27.0 0.6 5e-06 25.9 0.4 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF900 PF05990.7 ETO20926.1 - 1.3e-05 24.6 0.0 2.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 ETO20926.1 - 4.2e-05 23.3 0.0 8.1e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETO20926.1 - 0.0004 20.3 0.0 0.00062 19.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 ETO20926.1 - 0.057 13.0 0.0 0.15 11.6 0.0 1.8 1 0 0 1 1 1 0 Lipase (class 3) DUF3089 PF11288.3 ETO20926.1 - 0.071 12.2 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) RIO1 PF01163.17 ETO20927.1 - 0.011 15.1 0.2 0.028 13.7 0.1 1.7 1 0 0 1 1 1 0 RIO1 family ADP_ribosyl_GH PF03747.9 ETO20928.1 - 2e-12 47.4 0.2 5.9e-12 45.9 0.1 1.7 2 0 0 2 2 2 1 ADP-ribosylglycohydrolase Acyl-ACP_TE PF01643.12 ETO20928.1 - 0.036 13.0 0.1 0.051 12.5 0.1 1.2 1 0 0 1 1 1 0 Acyl-ACP thioesterase WD40 PF00400.27 ETO20929.1 - 6.7e-64 209.6 10.3 9.9e-14 50.6 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO20929.1 - 2.2e-11 43.8 0.4 0.0013 18.4 0.0 3.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO20929.1 - 1.3e-05 23.6 1.2 0.35 8.9 0.0 3.9 2 2 2 4 4 4 3 Nucleoporin Nup120/160 PD40 PF07676.7 ETO20929.1 - 7.1e-05 22.3 7.7 5.3 6.8 0.0 5.8 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 ETO20929.1 - 0.00015 20.9 0.5 0.9 8.5 0.0 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF1258) Cytochrom_D1 PF02239.11 ETO20929.1 - 0.02 13.1 0.0 0.18 10.0 0.0 2.2 1 1 0 2 2 2 0 Cytochrome D1 heme domain Resistin PF06954.6 ETO20929.1 - 0.028 14.7 0.5 4.6 7.5 0.0 3.6 4 0 0 4 4 4 0 Resistin Proteasome_A_N PF10584.4 ETO20929.1 - 0.073 12.4 0.2 85 2.6 0.0 4.0 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature DNA_pol3_delta PF06144.8 ETO20929.1 - 7.5 6.0 9.3 2.3 7.6 0.9 2.4 2 0 0 2 2 2 0 DNA polymerase III, delta subunit WD40 PF00400.27 ETO20930.1 - 1.4e-34 116.6 13.7 4.2e-13 48.6 0.0 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO20930.1 - 4.6e-07 28.3 1.1 0.025 12.7 0.2 3.0 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO20931.1 - 3.3e-07 30.1 1.2 0.049 13.8 0.0 3.9 4 1 1 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO20931.1 - 4.5e-05 22.9 0.7 0.52 9.9 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 ETO20931.1 - 0.00033 20.7 0.2 3 8.1 0.0 4.3 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO20931.1 - 0.004 16.8 0.3 7.3 6.5 0.0 3.9 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 ETO20931.1 - 0.062 13.2 1.9 0.92 9.5 0.3 3.3 4 0 0 4 4 4 0 Kelch motif DUF2684 PF10885.3 ETO20931.1 - 0.16 11.8 1.2 0.54 10.1 0.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2684) ARS2 PF04959.8 ETO20932.1 - 0.093 12.9 2.1 0.13 12.4 1.4 1.3 1 1 0 1 1 1 0 Arsenite-resistance protein 2 DUF948 PF06103.6 ETO20933.1 - 0.02 14.7 5.2 0.048 13.5 2.5 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.7 ETO20933.1 - 0.064 13.0 10.0 0.17 11.6 2.6 2.6 1 1 1 2 2 2 0 Laminin Domain II PEX-2N PF09263.5 ETO20933.1 - 0.082 13.2 0.2 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal V_ATPase_I PF01496.14 ETO20933.1 - 0.24 9.2 8.8 0.4 8.4 6.0 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF310 PF03750.8 ETO20933.1 - 0.29 11.3 8.3 0.94 9.6 0.9 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF310) zf-Sec23_Sec24 PF04810.10 ETO20935.1 - 1.1e-05 24.8 0.5 8.6e-05 22.0 0.0 2.2 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Menin PF05053.8 ETO20935.1 - 0.22 9.6 6.5 0.27 9.3 4.5 1.1 1 0 0 1 1 1 0 Menin DUF1117 PF06547.7 ETO20935.1 - 0.68 10.0 4.8 0.22 11.5 0.5 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1117) SprA-related PF12118.3 ETO20935.1 - 4.1 6.6 13.9 5.9 6.1 9.7 1.2 1 0 0 1 1 1 0 SprA-related family Peptidase_S80 PF07230.6 ETO20936.1 - 0.043 12.1 0.5 0.27 9.4 0.2 1.9 1 1 1 2 2 2 0 Bacteriophage T4-like capsid assembly protein (Gp20) Ras PF00071.17 ETO20937.1 - 2.4e-15 56.3 0.0 4.3e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO20937.1 - 4.2e-09 36.9 0.1 9.2e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 Miro-like protein Arch_ATPase PF01637.13 ETO20937.1 - 0.0056 16.4 0.3 0.011 15.3 0.0 1.6 2 0 0 2 2 2 1 Archaeal ATPase cobW PF02492.14 ETO20937.1 - 0.0084 15.5 0.2 0.025 14.0 0.0 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 ETO20937.1 - 0.064 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 ETO20937.1 - 0.12 12.0 0.1 0.38 10.4 0.0 2.0 2 2 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DNA_primase_lrg PF04104.9 ETO20938.1 - 8.4e-44 149.7 2.8 8.4e-44 149.7 1.9 1.6 2 1 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit TLP-20 PF06088.6 ETO20939.1 - 0.98 9.0 5.5 0.3 10.7 1.7 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Vps39_1 PF10366.4 ETO20940.1 - 8.2e-09 35.4 5.3 1.2e-07 31.6 3.7 2.2 1 1 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.15 ETO20940.1 - 0.001 18.7 1.3 0.0067 16.0 1.0 1.9 1 1 1 2 2 2 1 Region in Clathrin and VPS SPT6_acidic PF14632.1 ETO20940.1 - 0.047 13.8 2.2 0.05 13.7 0.3 1.8 2 0 0 2 2 2 0 Acidic N-terminal SPT6 CNH PF00780.17 ETO20941.1 - 1.8e-08 34.1 0.0 3.2e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 CNH domain Gb3_synth PF04572.7 ETO20941.1 - 0.038 13.6 0.3 0.076 12.7 0.2 1.5 1 0 0 1 1 1 0 Alpha 1,4-glycosyltransferase conserved region Viral_Beta_CD PF04530.7 ETO20942.1 - 0.017 15.2 0.1 0.017 15.2 0.0 3.0 3 0 0 3 3 3 0 Viral Beta C/D like family DUF912 PF06024.7 ETO20942.1 - 0.081 12.9 0.0 0.081 12.9 0.0 4.5 4 1 0 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Claudin_2 PF13903.1 ETO20942.1 - 4.2 7.0 10.1 3.6 7.2 2.3 3.0 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Peptidase_S10 PF00450.17 ETO20943.1 - 1.2e-41 143.2 1.6 1.4e-41 143.0 1.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase RRM_1 PF00076.17 ETO20944.1 - 1e-05 25.0 0.0 0.14 11.8 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO20944.1 - 2.6e-05 23.9 0.0 0.22 11.3 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO20944.1 - 0.0029 17.5 0.0 3.5 7.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF605 PF04652.11 ETO20944.1 - 8.3 5.6 26.5 13 5.0 18.4 1.3 1 0 0 1 1 1 0 Vta1 like Beta-Casp PF10996.3 ETO20945.1 - 1.9e-29 102.1 0.0 4.5e-29 100.9 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 ETO20945.1 - 9.7e-13 48.2 0.0 9.2e-12 45.0 0.0 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily CPSF73-100_C PF11718.3 ETO20945.1 - 1.2e-08 34.6 0.0 2.5e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Lactamase_B_2 PF12706.2 ETO20945.1 - 8.9e-06 25.3 0.6 1.7e-05 24.4 0.1 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 ETO20945.1 - 0.00026 20.7 0.1 0.00055 19.6 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 ETO20945.1 - 0.00058 19.6 0.1 0.0022 17.6 0.0 1.9 2 1 0 2 2 2 1 Beta-lactamase superfamily domain FAD_binding_1 PF00667.15 ETO20946.1 - 8.6e-25 87.4 0.0 8e-21 74.4 0.0 2.5 3 0 0 3 3 3 2 FAD binding domain NAD_binding_1 PF00175.16 ETO20946.1 - 4.1e-13 49.8 0.0 6.8e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain SARG PF15385.1 ETO20948.1 - 0.39 10.0 5.8 0.48 9.7 4.0 1.2 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein WD40 PF00400.27 ETO20949.1 - 5e-55 181.5 19.0 1e-10 41.0 0.5 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO20949.1 - 1.3e-11 43.4 8.3 0.02 13.0 0.2 6.0 1 1 5 6 6 6 6 Nucleoporin Nup120/160 His_Phos_1 PF00300.17 ETO20950.1 - 5.3e-09 36.3 0.0 2.3e-08 34.2 0.0 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) FYVE PF01363.16 ETO20950.1 - 0.00074 19.3 0.2 0.00074 19.3 0.1 2.7 2 1 1 3 3 3 1 FYVE zinc finger zf-C3HC4_2 PF13923.1 ETO20950.1 - 0.0068 16.4 5.7 0.0068 16.4 4.0 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO20950.1 - 0.78 9.4 15.4 0.028 14.0 3.4 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO20950.1 - 1.2 8.9 11.8 0.23 11.3 3.6 2.5 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.1 ETO20950.1 - 2.4 7.8 12.7 0.8 9.4 3.1 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO20950.1 - 5.9 6.7 16.2 0.025 14.3 3.6 2.7 3 0 0 3 3 3 0 zinc-RING finger domain NIF PF03031.13 ETO20951.1 - 1.7e-13 50.5 0.7 3.5e-13 49.5 0.5 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 ETO20951.1 - 0.0012 19.0 0.4 0.0052 17.0 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 ETO20951.1 - 0.0014 18.2 0.3 0.0028 17.3 0.2 1.5 1 0 0 1 1 1 1 Acid Phosphatase Pam16 PF03656.8 ETO20952.1 - 0.052 13.3 0.5 0.052 13.3 0.3 1.9 2 0 0 2 2 2 0 Pam16 Ycf54 PF10674.4 ETO20952.1 - 0.27 11.4 5.6 14 5.8 1.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2488) Slu7 PF11708.3 ETO20952.1 - 0.38 10.4 9.1 0.6 9.8 6.3 1.3 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor DAGK_acc PF00609.14 ETO20953.1 - 1e-17 64.7 0.0 4e-17 62.8 0.0 2.0 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 ETO20953.1 - 0.0036 16.7 0.2 0.013 14.9 0.0 2.0 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain She9_MDM33 PF05546.6 ETO20953.1 - 0.02 14.4 2.1 0.02 14.4 1.5 2.6 3 0 0 3 3 3 0 She9 / Mdm33 family Vps16_N PF04841.8 ETO20954.1 - 6.9e-18 64.3 0.0 3.7e-16 58.6 0.0 2.0 1 1 0 1 1 1 1 Vps16, N-terminal region Peptidase_S10 PF00450.17 ETO20955.1 - 7.1e-39 134.1 1.2 3.2e-24 85.8 0.1 2.2 2 0 0 2 2 2 2 Serine carboxypeptidase SHR3_chaperone PF08229.6 ETO20955.1 - 0.091 11.6 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 ER membrane protein SH3 WD40 PF00400.27 ETO20957.1 - 5e-29 99.0 8.8 2.5e-06 27.1 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Nop14 PF04147.7 ETO20957.1 - 0.00071 17.6 22.6 0.001 17.0 15.6 1.2 1 0 0 1 1 1 1 Nop14-like family Nucleoporin_N PF08801.6 ETO20957.1 - 0.0026 16.5 0.1 1.6 7.3 0.0 2.5 2 0 0 2 2 2 2 Nup133 N terminal like CENP-T PF15511.1 ETO20957.1 - 4.4 6.4 17.0 6 6.0 11.8 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T BTV_NS2 PF04514.7 ETO20957.1 - 5.3 5.8 18.7 8.7 5.1 13.0 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 IncA PF04156.9 ETO20958.1 - 1.4 8.4 42.2 5.4 6.5 12.1 2.2 1 1 1 2 2 2 0 IncA protein Baculo_PEP_C PF04513.7 ETO20958.1 - 1.6 8.5 19.8 2.9 7.7 6.7 3.4 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoO PF09769.4 ETO20958.1 - 3.1 7.4 11.0 4.2 7.0 2.0 2.4 2 0 0 2 2 2 0 Apolipoprotein O TBPIP PF07106.8 ETO20958.1 - 9.2 5.7 45.0 0.08 12.4 2.6 3.7 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) C2 PF00168.25 ETO20959.1 - 7.8e-13 48.0 0.1 2e-12 46.7 0.1 1.8 1 0 0 1 1 1 1 C2 domain TBPIP PF07106.8 ETO20960.1 - 2.6e-21 75.9 8.0 2.4e-20 72.7 5.5 2.0 1 1 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Toxin_17 PF08086.6 ETO20960.1 - 0.021 14.8 0.8 0.043 13.8 0.6 1.5 1 0 0 1 1 1 0 Ergtoxin family PilJ PF13675.1 ETO20960.1 - 0.042 14.1 1.9 0.082 13.2 1.3 1.5 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term IncA PF04156.9 ETO20960.1 - 0.78 9.3 7.0 1.2 8.7 4.8 1.5 1 1 0 1 1 1 0 IncA protein ERp29 PF07749.7 ETO20961.1 - 1.7e-17 63.8 0.0 2.5e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Sulfotransfer_3 PF13469.1 ETO20962.1 - 0.077 13.9 0.0 0.089 13.7 0.0 1.1 1 0 0 1 1 1 0 Sulfotransferase family Pex14_N PF04695.8 ETO20964.1 - 0.0009 19.2 3.1 0.0011 18.9 2.1 1.1 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Sec62 PF03839.11 ETO20964.1 - 0.0013 18.1 0.6 0.0014 18.0 0.4 1.1 1 0 0 1 1 1 1 Translocation protein Sec62 UPF0560 PF10577.4 ETO20964.1 - 0.031 12.5 5.5 0.034 12.4 3.8 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Striatin PF08232.7 ETO20964.1 - 0.035 14.4 5.5 0.045 14.0 3.8 1.1 1 0 0 1 1 1 0 Striatin family Inhibitor_I71 PF12628.2 ETO20964.1 - 0.16 11.5 5.4 0.19 11.3 3.8 1.1 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor DUF4526 PF15029.1 ETO20964.1 - 0.25 10.8 1.3 0.31 10.5 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4526) DUF2126 PF09899.4 ETO20964.1 - 0.3 9.0 2.0 0.31 9.0 1.4 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Neur_chan_memb PF02932.11 ETO20964.1 - 0.42 10.4 2.4 0.48 10.2 1.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3682 PF12446.3 ETO20964.1 - 1.3 9.2 9.0 1.7 8.9 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Macoilin PF09726.4 ETO20964.1 - 1.4 7.1 6.5 1.4 7.0 4.5 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF3792 PF12670.2 ETO20965.1 - 4.4 7.2 13.6 0.67 9.8 6.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3792) zf-TRAF PF02176.13 ETO20966.1 - 1.9e-05 24.9 0.9 1.9e-05 24.9 0.6 3.4 3 1 1 4 4 4 1 TRAF-type zinc finger DUF4458 PF14660.1 ETO20966.1 - 0.12 12.4 2.4 0.13 12.2 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4458) NnrU PF07298.6 ETO20967.1 - 1.6e-14 53.7 0.2 2.1e-14 53.3 0.2 1.1 1 0 0 1 1 1 1 NnrU protein TMEM192 PF14802.1 ETO20969.1 - 5.5e-05 22.1 1.6 6.3e-05 21.9 1.1 1.0 1 0 0 1 1 1 1 TMEM192 family PDR_CDR PF06422.7 ETO20969.1 - 0.017 14.7 1.1 0.017 14.7 0.7 1.9 2 0 0 2 2 2 0 CDR ABC transporter PqiA PF04403.8 ETO20969.1 - 0.044 13.3 0.6 0.2 11.2 0.1 2.1 2 1 0 2 2 2 0 Paraquat-inducible protein A DUF4013 PF13197.1 ETO20969.1 - 0.093 12.0 3.8 0.13 11.6 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) DUF1240 PF06836.7 ETO20969.1 - 0.22 11.7 3.2 0.77 10.0 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1240) Melibiase PF02065.13 ETO20970.1 - 1.2e-09 37.3 0.0 1.4e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Melibiase Afi1 PF07792.7 ETO20970.1 - 0.061 13.3 0.1 0.072 13.1 0.1 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking 2TM PF13239.1 ETO20971.1 - 0.0015 18.5 5.8 0.0051 16.8 1.4 2.5 2 1 0 2 2 2 1 2TM domain Tetraspannin PF00335.15 ETO20971.1 - 0.0019 17.5 0.0 0.0019 17.5 0.0 2.7 1 1 1 2 2 2 1 Tetraspanin family MIG-14_Wnt-bd PF06664.7 ETO20971.1 - 0.0044 15.8 11.3 0.0088 14.9 7.8 1.5 1 1 0 1 1 1 1 Wnt-binding factor required for Wnt secretion DUF4184 PF13803.1 ETO20971.1 - 0.018 14.3 5.9 0.057 12.7 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4184) DUF202 PF02656.10 ETO20971.1 - 0.019 15.1 0.7 1.6 8.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF202) PQ-loop PF04193.9 ETO20971.1 - 0.049 13.1 2.4 0.11 12.1 0.1 2.4 2 0 0 2 2 2 0 PQ loop repeat DUF4064 PF13273.1 ETO20971.1 - 0.058 13.5 6.5 0.67 10.0 0.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Sigma_reg_N PF13800.1 ETO20971.1 - 0.063 13.3 11.6 0.99 9.4 0.2 3.6 3 1 0 3 3 3 0 Sigma factor regulator N-terminal LtrA PF06772.6 ETO20971.1 - 0.07 12.0 7.5 0.51 9.2 0.2 2.1 2 0 0 2 2 2 0 Bacterial low temperature requirement A protein (LtrA) DUF1230 PF06799.6 ETO20971.1 - 0.085 12.7 9.0 6.8 6.5 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1230) DUF4401 PF14351.1 ETO20971.1 - 0.28 10.1 6.4 0.91 8.4 0.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4401) DUF3429 PF11911.3 ETO20971.1 - 0.34 10.8 5.8 2.2 8.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3429) EphA2_TM PF14575.1 ETO20971.1 - 0.57 10.6 5.9 2.9 8.3 0.0 3.5 2 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain BCHF PF07284.6 ETO20971.1 - 0.85 9.4 8.8 0.5 10.2 2.0 2.2 2 0 0 2 2 2 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) DUF373 PF04123.8 ETO20971.1 - 0.9 8.4 4.8 1.6 7.6 3.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF373) DUF1129 PF06570.6 ETO20971.1 - 2.3 7.4 10.0 0.79 8.9 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) Shisa PF13908.1 ETO20971.1 - 3.4 7.8 4.9 4 7.5 0.0 2.7 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator SCO1-SenC PF02630.9 ETO20972.1 - 2.7e-36 124.7 0.1 3e-36 124.6 0.1 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 ETO20972.1 - 8.5e-05 22.2 0.0 0.00011 21.8 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 ETO20972.1 - 0.00096 19.2 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like WD40 PF00400.27 ETO20973.1 - 2.4e-83 271.3 10.1 1.4e-13 50.1 0.0 7.0 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO20973.1 - 2.5e-12 46.9 0.0 0.00035 20.3 0.0 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO20973.1 - 7.7e-11 40.8 2.4 3.6e-06 25.5 0.0 3.0 1 1 2 3 3 3 3 Cytochrome D1 heme domain Nup160 PF11715.3 ETO20973.1 - 1.4e-09 36.6 0.2 0.0093 14.1 0.0 4.8 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO20973.1 - 2.4e-05 23.2 4.2 0.067 11.9 0.3 5.2 1 1 2 4 4 4 1 Nup133 N terminal like Nbas_N PF15492.1 ETO20973.1 - 2.7e-05 23.4 1.8 1.6 7.7 0.0 5.2 1 1 4 6 6 6 2 Neuroblastoma-amplified sequence, N terminal Resistin PF06954.6 ETO20973.1 - 0.0027 17.9 0.0 25 5.2 0.0 3.4 1 1 1 3 3 3 0 Resistin IKI3 PF04762.7 ETO20973.1 - 0.0063 14.4 0.1 0.49 8.1 0.1 2.1 1 1 1 2 2 2 2 IKI3 family Proteasome_A_N PF10584.4 ETO20973.1 - 0.0097 15.2 7.7 6.1 6.2 0.0 5.3 6 0 0 6 6 6 1 Proteasome subunit A N-terminal signature PQQ_2 PF13360.1 ETO20973.1 - 0.011 15.2 0.1 0.82 9.0 0.0 2.6 1 1 2 3 3 3 0 PQQ-like domain DUF1258 PF06869.7 ETO20973.1 - 0.055 12.5 0.1 30 3.6 0.0 3.2 1 1 0 3 3 3 0 Protein of unknown function (DUF1258) PD40 PF07676.7 ETO20973.1 - 3.9 7.2 16.1 12 5.6 0.0 5.5 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Kelch_6 PF13964.1 ETO20974.1 - 3.9e-09 36.2 3.9 0.00012 22.1 0.2 3.5 2 1 1 3 3 3 2 Kelch motif Kelch_1 PF01344.20 ETO20974.1 - 1.9e-06 27.2 6.2 0.0074 15.8 0.8 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 ETO20974.1 - 7.4e-06 25.9 0.1 0.00055 20.0 0.0 3.6 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO20974.1 - 0.00014 21.5 4.4 0.031 14.0 0.1 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO20974.1 - 0.031 14.2 7.6 0.16 11.9 0.5 3.4 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.1 ETO20974.1 - 0.14 11.9 3.0 0.2 11.4 0.1 2.8 4 0 0 4 4 4 0 Galactose oxidase, central domain Ras PF00071.17 ETO20975.1 - 1.9e-31 108.6 0.0 3e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO20975.1 - 3e-12 47.0 0.0 5.9e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO20975.1 - 2.8e-08 33.2 0.0 4.3e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO20975.1 - 1.2e-07 31.3 0.1 3e-06 26.8 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 ETO20975.1 - 0.00036 20.4 0.0 0.00094 19.1 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 ETO20975.1 - 0.031 14.4 0.0 0.093 12.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 ETO20975.1 - 0.051 13.1 0.1 0.14 11.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 ETO20975.1 - 0.097 11.8 0.0 0.28 10.3 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_19 PF13245.1 ETO20975.1 - 0.099 12.4 0.0 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 ETO20975.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain zf-CCCH_2 PF14608.1 ETO20976.1 - 1.4 9.0 18.4 1.6 8.8 0.2 3.3 3 1 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type SH3_1 PF00018.23 ETO20977.1 - 5.1e-10 38.5 0.3 8.5e-10 37.8 0.2 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 ETO20977.1 - 1.5e-05 24.4 0.5 3.4e-05 23.3 0.3 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 ETO20977.1 - 3.3e-05 23.3 0.1 7.5e-05 22.1 0.1 1.6 1 1 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 ETO20977.1 - 0.039 14.1 0.4 0.079 13.1 0.3 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain DNA_pol_viral_N PF00242.12 ETO20977.1 - 0.1 11.6 7.3 0.13 11.2 5.0 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain HATPase_c PF02518.21 ETO20977.1 - 0.13 11.9 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SARG PF15385.1 ETO20977.1 - 0.28 10.5 23.4 0.33 10.2 16.2 1.1 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein Spc7_N PF15402.1 ETO20977.1 - 0.78 7.6 23.2 0.93 7.4 16.1 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF3827 PF12877.2 ETO20977.1 - 1.2 7.1 12.4 1.4 6.9 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) SPATIAL PF15256.1 ETO20977.1 - 1.5 8.8 14.4 1.9 8.4 10.0 1.1 1 0 0 1 1 1 0 SPATIAL GKAP PF03359.8 ETO20977.1 - 5.3 6.5 20.3 7.1 6.1 14.1 1.2 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein PAT1 PF09770.4 ETO20977.1 - 6.4 4.8 27.9 8 4.5 19.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PsbW PF07123.7 ETO20977.1 - 9.2 6.3 7.6 13 5.8 5.3 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) Transposase_mut PF00872.13 ETO20978.1 - 0.038 12.5 1.5 0.056 11.9 1.1 1.2 1 0 0 1 1 1 0 Transposase, Mutator family G-alpha PF00503.15 ETO20979.1 - 4.6e-27 94.6 0.2 5.8e-27 94.3 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Rad17 PF03215.10 ETO20979.1 - 0.0068 15.1 0.1 0.009 14.7 0.1 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein MMR_HSR1 PF01926.18 ETO20979.1 - 0.017 15.0 0.2 0.026 14.4 0.1 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 ETO20979.1 - 0.021 14.3 0.0 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DAP3 PF10236.4 ETO20979.1 - 0.046 12.6 0.1 0.074 11.9 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.1 ETO20979.1 - 0.062 12.8 0.1 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 ETO20979.1 - 0.063 13.1 0.0 0.11 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain MutS_V PF00488.16 ETO20979.1 - 0.082 12.2 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 MutS domain V G-alpha PF00503.15 ETO20980.1 - 3.3e-29 101.7 2.5 3.6e-29 101.6 1.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit ATP_bind_1 PF03029.12 ETO20980.1 - 0.038 13.5 0.2 0.041 13.4 0.1 1.0 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein PMEI PF04043.10 ETO20980.1 - 0.045 13.6 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Sec5 PF15469.1 ETO20980.1 - 0.064 12.9 0.1 0.074 12.7 0.1 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec5 A_deaminase PF00962.17 ETO20981.1 - 7.2e-90 301.2 0.0 3.2e-89 299.1 0.0 2.1 1 1 0 1 1 1 1 Adenosine/AMP deaminase Ras PF00071.17 ETO20982.1 - 3.1e-05 23.4 0.1 4.2e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Ras family Caveolin PF01146.12 ETO20982.1 - 0.031 13.8 2.9 0.028 14.0 1.5 1.3 1 1 0 1 1 1 0 Caveolin Nodulin_late PF07127.6 ETO20983.1 - 0.18 11.9 6.6 3.2 7.9 0.2 3.0 2 2 0 2 2 2 0 Late nodulin protein peroxidase PF00141.18 ETO20984.1 - 0.057 12.9 0.1 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 Peroxidase Xpo1 PF08389.7 ETO20987.1 - 0.17 11.8 2.5 0.15 12.0 0.3 1.9 2 0 0 2 2 2 0 Exportin 1-like protein Spore_coat_CotO PF14153.1 ETO20988.1 - 0.15 11.4 8.8 0.17 11.3 6.1 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Presenilin PF01080.12 ETO20988.1 - 0.18 10.6 1.2 0.19 10.5 0.9 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.7 ETO20988.1 - 0.25 11.2 13.2 0.3 10.9 9.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.7 ETO20988.1 - 0.43 9.2 3.4 0.54 8.9 2.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF1675 PF07897.6 ETO20988.1 - 4.8 6.9 11.3 6.2 6.6 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Sec62 PF03839.11 ETO20988.1 - 9.7 5.5 7.2 13 5.0 5.0 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 ABC_membrane_3 PF13748.1 ETO20989.1 - 5.7 5.8 6.9 2.2 7.2 2.8 1.8 2 0 0 2 2 2 0 ABC transporter transmembrane region Peptidase_C97 PF05903.9 ETO20990.1 - 0.053 13.2 2.9 0.12 12.1 2.0 1.6 1 1 0 1 1 1 0 PPPDE putative peptidase domain DUF4502 PF14950.1 ETO20991.1 - 0.031 13.4 0.9 0.038 13.1 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4502) HSBP1 PF06825.7 ETO20991.1 - 0.079 12.5 0.1 0.2 11.2 0.1 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 AAA_18 PF13238.1 ETO20991.1 - 0.25 11.6 2.5 0.52 10.6 1.7 1.6 1 0 0 1 1 1 0 AAA domain DUF2418 PF10332.4 ETO20991.1 - 3.9 7.8 8.3 3 8.1 0.2 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2418) Daxx PF03344.10 ETO20992.1 - 0.0012 17.4 8.8 0.0012 17.4 6.1 1.2 1 0 0 1 1 1 1 Daxx Family Spore_coat_CotO PF14153.1 ETO20992.1 - 0.0037 16.7 9.2 0.0062 16.0 6.4 1.4 1 0 0 1 1 1 1 Spore coat protein CotO CDC45 PF02724.9 ETO20992.1 - 0.0097 13.9 4.1 0.012 13.6 2.8 1.1 1 0 0 1 1 1 1 CDC45-like protein Yip1 PF04893.12 ETO20992.1 - 0.03 13.8 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 Yip1 domain LMBR1 PF04791.11 ETO20992.1 - 0.29 9.6 7.8 0.038 12.5 2.6 1.5 2 0 0 2 2 2 0 LMBR1-like membrane protein DUF2457 PF10446.4 ETO20992.1 - 1.2 7.7 18.3 1.9 7.1 12.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF605 PF04652.11 ETO20992.1 - 1.3 8.3 23.1 1.9 7.8 16.0 1.4 1 1 0 1 1 1 0 Vta1 like Nop14 PF04147.7 ETO20992.1 - 3.5 5.4 18.7 5.8 4.6 13.0 1.2 1 0 0 1 1 1 0 Nop14-like family Neur_chan_memb PF02932.11 ETO20992.1 - 8.9 6.1 21.8 0.46 10.3 0.7 2.1 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region RE_TaqI PF09573.5 ETO20993.1 - 0.019 14.0 0.3 52 2.8 0.0 4.7 2 2 3 6 6 6 0 TaqI restriction endonuclease DUF4160 PF13711.1 ETO20993.1 - 2.1 8.2 6.8 77 3.2 0.0 5.2 5 1 0 5 5 5 0 Domain of unknown function (DUF4160) Chitin_synth_2 PF03142.10 ETO20995.1 - 0.011 14.1 0.0 0.016 13.6 0.0 1.3 1 0 0 1 1 1 0 Chitin synthase ubiquitin PF00240.18 ETO20996.1 - 1.2e-17 63.1 0.5 1.6e-17 62.6 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 ETO20996.1 - 6.2e-09 35.4 0.8 8.8e-09 34.9 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 ETO20996.1 - 4.3e-06 26.8 0.8 4.8e-06 26.6 0.6 1.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 ETO20996.1 - 0.0002 21.1 0.2 0.00031 20.5 0.2 1.4 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.5 ETO20996.1 - 0.00059 20.3 0.1 0.00088 19.7 0.0 1.4 1 1 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_2 PF14560.1 ETO20996.1 - 0.005 17.0 1.2 0.017 15.3 0.8 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain SecA_PP_bind PF01043.15 ETO20998.1 - 1.3e-07 31.9 0.0 5.8e-07 29.8 0.0 2.2 1 0 0 1 1 1 1 SecA preprotein cross-linking domain Helicase_C PF00271.26 ETO20998.1 - 0.00042 20.1 0.2 0.0015 18.3 0.2 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF308 PF03729.8 ETO20998.1 - 1.7 8.7 10.4 1.6 8.7 3.0 3.0 2 1 1 3 3 3 0 Short repeat of unknown function (DUF308) SecA_DEAD PF07517.9 ETO20999.1 - 0.0014 17.9 0.0 0.71 9.1 0.0 2.5 1 1 1 2 2 2 2 SecA DEAD-like domain Proteasome PF00227.21 ETO21000.1 - 3.4e-46 156.9 0.1 4.8e-46 156.4 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 ETO21000.1 - 0.11 11.7 1.9 0.16 11.2 0.0 2.2 2 0 0 2 2 2 0 Proteasome beta subunits C terminal V_ATPase_I PF01496.14 ETO21001.1 - 0.25 9.1 7.8 0.32 8.7 5.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NHase_alpha PF02979.11 ETO21002.1 - 4.3e-41 140.2 0.0 7.7e-40 136.1 0.0 2.5 2 1 0 2 2 2 1 Nitrile hydratase, alpha chain NHase_beta PF02211.10 ETO21002.1 - 1.2e-22 80.7 10.2 1e-18 67.9 2.5 3.7 1 1 1 3 3 3 2 Nitrile hydratase beta subunit DUF1392 PF07154.6 ETO21002.1 - 0.0016 18.2 0.7 1.2 8.9 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1392) Sigma_reg_C PF13791.1 ETO21004.1 - 0.046 13.7 0.2 0.28 11.2 0.0 2.1 2 1 0 2 2 2 0 Sigma factor regulator C-terminal YesK PF14150.1 ETO21004.1 - 1.7 8.7 8.0 0.73 9.9 3.5 1.9 2 0 0 2 2 2 0 YesK-like protein ADP_ribosyl_GH PF03747.9 ETO21005.1 - 9.6e-33 114.1 0.0 3.4e-32 112.3 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylglycohydrolase Mitofilin PF09731.4 ETO21006.1 - 0.004 15.8 18.0 0.004 15.8 12.5 2.1 2 0 0 2 2 2 1 Mitochondrial inner membrane protein DUF3810 PF12725.2 ETO21006.1 - 1.3 7.8 6.3 0.06 12.2 0.2 1.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3810) Flagellin_N PF00669.15 ETO21006.1 - 1.6 8.5 7.8 0.52 10.1 3.0 2.0 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region zf-RING_2 PF13639.1 ETO21007.1 - 7.8e-07 28.8 7.8 1.5e-06 27.9 5.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO21007.1 - 1.3e-05 25.0 8.4 3.6e-05 23.7 5.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO21007.1 - 2e-05 24.1 6.7 5.1e-05 22.8 4.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO21007.1 - 2.6e-05 23.8 6.0 6.7e-05 22.5 4.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 ETO21007.1 - 0.0001 21.9 6.6 0.0001 21.9 4.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 ETO21007.1 - 0.00022 21.0 7.9 0.00058 19.6 5.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 ETO21007.1 - 0.0048 16.5 2.6 0.0048 16.5 1.8 3.1 2 1 1 3 3 3 1 RING-type zinc-finger APC_CDC26 PF10471.4 ETO21007.1 - 0.021 15.5 2.6 0.021 15.5 1.8 3.4 3 1 0 3 3 2 0 Anaphase-promoting complex APC subunit 1 Baculo_IE-1 PF05290.6 ETO21007.1 - 0.034 13.8 7.8 0.099 12.3 5.4 1.8 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Tmemb_14 PF03647.8 ETO21007.1 - 0.15 12.4 0.1 0.59 10.5 0.0 1.9 2 0 0 2 2 2 0 Transmembrane proteins 14C zf-rbx1 PF12678.2 ETO21007.1 - 0.28 11.3 7.2 0.23 11.6 3.0 2.3 2 1 0 2 2 2 0 RING-H2 zinc finger DM PF00751.13 ETO21007.1 - 1 8.9 9.4 2.8 7.5 6.5 1.7 1 0 0 1 1 1 0 DM DNA binding domain PB1 PF00564.19 ETO21008.1 - 0.0014 18.2 0.3 0.82 9.3 0.1 2.9 3 0 0 3 3 3 2 PB1 domain DUF2347 PF09804.4 ETO21008.1 - 0.14 11.4 0.7 0.23 10.7 0.5 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) DUF4604 PF15377.1 ETO21009.1 - 0.0074 16.5 12.9 0.0074 16.5 9.0 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4604) DUF4109 PF13397.1 ETO21009.1 - 0.01 16.2 1.2 0.01 16.2 0.8 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4109) ERp29 PF07749.7 ETO21009.1 - 1.3 9.6 9.1 2.5 8.7 4.2 2.5 1 1 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain G-alpha PF00503.15 ETO21010.1 - 4.9e-89 298.7 2.4 6.2e-89 298.3 1.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO21010.1 - 1.4e-11 43.9 2.0 5e-08 32.3 0.3 3.1 2 1 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 ETO21010.1 - 7e-05 23.3 1.7 0.097 13.1 0.0 2.9 3 0 0 3 3 3 2 Miro-like protein Gtr1_RagA PF04670.7 ETO21010.1 - 0.0056 15.8 3.9 0.11 11.6 0.1 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 ETO21010.1 - 0.0089 15.5 0.1 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 ETO21010.1 - 0.025 14.5 0.1 5.3 7.0 0.0 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 ETO21010.1 - 0.039 13.4 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Mg_chelatase PF01078.16 ETO21010.1 - 0.041 13.0 0.0 0.069 12.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 ETO21010.1 - 0.073 12.9 0.1 0.34 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 ETO21010.1 - 0.081 11.8 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 ETO21010.1 - 0.11 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Daxx PF03344.10 ETO21011.1 - 0.003 16.1 13.6 0.003 16.1 9.5 2.6 3 0 0 3 3 3 2 Daxx Family Cnd2 PF05786.9 ETO21011.1 - 0.074 11.5 34.5 0.033 12.7 8.2 3.2 3 0 0 3 3 3 0 Condensin complex subunit 2 CENP-T PF15511.1 ETO21011.1 - 0.57 9.3 39.7 0.14 11.3 7.6 2.8 3 0 0 3 3 3 0 Centromere kinetochore component CENP-T SprA-related PF12118.3 ETO21011.1 - 0.59 9.4 39.5 0.06 12.6 9.6 3.1 3 0 0 3 3 3 0 SprA-related family Mpp10 PF04006.7 ETO21011.1 - 1.2 7.4 46.2 0.032 12.6 6.0 2.2 2 0 0 2 2 2 0 Mpp10 protein SDA1 PF05285.7 ETO21011.1 - 4.5 6.4 58.5 3.5 6.8 23.5 2.4 2 0 0 2 2 2 0 SDA1 Nop14 PF04147.7 ETO21011.1 - 4.7 5.0 62.0 0.069 11.0 20.0 2.9 3 0 0 3 3 3 0 Nop14-like family Acyl-CoA_dh_1 PF00441.19 ETO21013.1 - 2.2e-14 53.8 0.1 1.6e-07 31.5 0.0 2.2 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 ETO21013.1 - 0.09 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain AP4E_app_platf PF14807.1 ETO21014.1 - 2e-08 34.3 0.0 5.3e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform Adaptin_N PF01602.15 ETO21015.1 - 5.9e-41 140.3 0.7 3e-35 121.5 0.0 2.0 2 0 0 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.1 ETO21015.1 - 0.021 15.3 0.0 0.072 13.6 0.0 2.0 1 0 0 1 1 1 0 HEAT-like repeat NUDIX_2 PF13869.1 ETO21016.1 - 3.2e-42 144.0 0.2 3.8e-42 143.7 0.1 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase Nop14 PF04147.7 ETO21017.1 - 0.044 11.7 22.7 0.058 11.3 15.7 1.1 1 0 0 1 1 1 0 Nop14-like family Zip PF02535.17 ETO21017.1 - 0.075 12.0 1.7 0.12 11.3 1.2 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Daxx PF03344.10 ETO21017.1 - 0.32 9.4 27.1 0.45 8.9 18.8 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 ETO21017.1 - 0.37 8.7 17.9 0.54 8.2 12.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 ETO21017.1 - 0.7 9.2 21.4 1.1 8.6 14.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Tim54 PF11711.3 ETO21017.1 - 2.6 6.5 9.4 3.9 5.9 6.5 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Sec62 PF03839.11 ETO21017.1 - 2.9 7.2 9.2 29 3.9 4.7 2.2 2 0 0 2 2 2 0 Translocation protein Sec62 TFIIF_alpha PF05793.7 ETO21017.1 - 3.1 6.0 24.5 3.9 5.7 17.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GOLD_2 PF13897.1 ETO21017.1 - 4.8 7.4 8.8 13 5.9 6.1 1.8 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking SDA1 PF05285.7 ETO21017.1 - 9.4 5.4 26.7 14 4.8 18.5 1.1 1 0 0 1 1 1 0 SDA1 PA26 PF04636.8 ETO21020.1 - 9.6e-17 60.8 6.0 1.2e-16 60.5 4.2 1.1 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) DUF4056 PF13265.1 ETO21020.1 - 0.041 12.8 0.1 0.054 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4056) TPX2 PF06886.6 ETO21021.1 - 8.4 6.5 23.6 0.59 10.2 7.1 4.2 3 0 0 3 3 3 0 Targeting protein for Xklp2 (TPX2) Glyco_tranf_2_4 PF13704.1 ETO21022.1 - 2.4e-05 24.5 0.1 0.00036 20.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.22 ETO21022.1 - 0.00025 20.4 0.3 0.00098 18.5 0.1 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 92 Aph-1 PF06105.7 ETO21023.1 - 4.5e-22 78.4 15.0 5.4e-22 78.2 10.4 1.0 1 0 0 1 1 1 1 Aph-1 protein Ax_dynein_light PF10211.4 ETO21026.1 - 6.3e-81 270.7 15.7 7.5e-81 270.5 10.9 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain ERM PF00769.14 ETO21026.1 - 0.00041 19.9 18.4 0.00075 19.1 12.7 1.4 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Tropomyosin_1 PF12718.2 ETO21026.1 - 0.0011 18.8 20.4 0.0023 17.8 14.1 1.5 1 0 0 1 1 1 1 Tropomyosin like APG6 PF04111.7 ETO21026.1 - 0.0059 15.6 12.1 0.0086 15.1 8.4 1.3 1 0 0 1 1 1 1 Autophagy protein Apg6 Jnk-SapK_ap_N PF09744.4 ETO21026.1 - 0.012 15.6 13.3 0.026 14.5 9.2 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Syntaxin-6_N PF09177.6 ETO21026.1 - 0.012 15.9 8.8 0.036 14.4 6.1 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF342 PF03961.8 ETO21026.1 - 0.029 12.8 11.2 0.038 12.4 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Mnd1 PF03962.10 ETO21026.1 - 0.054 13.1 17.1 0.13 11.9 11.9 1.6 1 0 0 1 1 1 0 Mnd1 family Sin3_corepress PF08295.7 ETO21026.1 - 0.077 12.7 5.5 0.13 12.0 3.2 1.9 1 1 0 1 1 1 0 Sin3 family co-repressor DUF724 PF05266.9 ETO21026.1 - 0.079 12.5 13.0 0.039 13.5 7.6 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF724) Prominin PF05478.6 ETO21026.1 - 0.092 10.2 3.8 0.097 10.1 2.7 1.1 1 0 0 1 1 1 0 Prominin bZIP_1 PF00170.16 ETO21026.1 - 0.12 12.3 18.1 0.19 11.7 2.3 2.6 1 1 1 2 2 2 0 bZIP transcription factor HAUS6_N PF14661.1 ETO21026.1 - 0.25 10.6 8.7 1.1 8.5 6.5 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus FlaC_arch PF05377.6 ETO21026.1 - 0.3 10.9 10.2 3.5 7.5 1.3 2.7 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Atg14 PF10186.4 ETO21026.1 - 0.41 9.5 15.7 0.53 9.1 10.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HSP70 PF00012.15 ETO21026.1 - 0.51 8.1 7.4 0.66 7.8 5.2 1.1 1 0 0 1 1 1 0 Hsp70 protein ADIP PF11559.3 ETO21026.1 - 0.7 9.7 19.7 1.5 8.7 13.7 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3573 PF12097.3 ETO21026.1 - 0.86 8.1 2.8 1.3 7.5 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Ndufs5 PF10200.4 ETO21026.1 - 0.87 9.6 4.9 1.9 8.5 3.4 1.6 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Syntaxin PF00804.20 ETO21026.1 - 0.96 9.6 12.1 2.1 8.5 8.4 1.6 1 0 0 1 1 1 0 Syntaxin EMP24_GP25L PF01105.19 ETO21026.1 - 1.2 8.8 8.5 0.43 10.2 3.5 2.0 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD V_ATPase_I PF01496.14 ETO21026.1 - 1.4 6.7 9.5 1.7 6.3 6.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc24 PF08286.6 ETO21026.1 - 1.6 8.4 16.1 2.4 7.8 8.3 2.8 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 HALZ PF02183.13 ETO21026.1 - 2.4 7.9 15.7 0.61 9.8 1.2 3.6 3 1 0 3 3 3 0 Homeobox associated leucine zipper OmpH PF03938.9 ETO21026.1 - 3.2 7.6 16.3 3 7.7 10.5 1.6 2 0 0 2 2 1 0 Outer membrane protein (OmpH-like) DUF972 PF06156.8 ETO21026.1 - 3.8 7.9 13.7 16 5.8 9.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF2681 PF10883.3 ETO21026.1 - 7.3 6.8 15.2 0.78 9.9 3.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) OPA3 PF07047.7 ETO21026.1 - 8.1 6.2 19.7 2.1 8.1 3.5 3.5 2 1 0 2 2 2 0 Optic atrophy 3 protein (OPA3) GvpL_GvpF PF06386.6 ETO21026.1 - 8.1 5.9 11.6 4.7 6.7 6.7 1.6 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Ribonuc_red_sm PF00268.16 ETO21027.1 - 1.1e-86 290.3 0.6 1.4e-86 290.0 0.4 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Ribonuc_red_sm PF00268.16 ETO21028.1 - 5.3e-19 68.2 1.4 7.4e-19 67.8 1.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain TF_AP-2 PF03299.9 ETO21028.1 - 0.25 10.8 2.4 0.91 9.0 0.3 2.0 1 1 1 2 2 2 0 Transcription factor AP-2 ABC2_membrane_3 PF12698.2 ETO21029.1 - 0.0017 17.4 0.0 0.0019 17.2 0.0 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF1108 PF06531.6 ETO21029.1 - 0.043 13.9 0.3 0.078 13.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1108) Daxx PF03344.10 ETO21029.1 - 0.059 11.8 8.4 0.064 11.7 5.8 1.0 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 ETO21029.1 - 0.12 10.3 2.7 0.16 9.9 1.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Isy1 PF06246.7 ETO21029.1 - 0.61 9.4 6.0 0.76 9.1 4.2 1.1 1 0 0 1 1 1 0 Isy1-like splicing family Nop14 PF04147.7 ETO21029.1 - 1.5 6.6 13.6 1.7 6.4 9.4 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 ETO21029.1 - 1.6 7.6 12.1 1.8 7.5 8.4 1.0 1 0 0 1 1 1 0 BUD22 DAP PF15228.1 ETO21029.1 - 2.3 9.0 10.1 0.18 12.5 1.0 2.1 1 1 1 2 2 2 0 Death-associated protein SDA1 PF05285.7 ETO21029.1 - 3.2 6.9 13.9 3.9 6.6 9.6 1.1 1 0 0 1 1 1 0 SDA1 SAPS PF04499.10 ETO21029.1 - 6.5 5.2 7.7 7.8 5.0 5.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2457 PF10446.4 ETO21030.1 - 4.9 5.7 16.3 6 5.4 11.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Chorein_N PF12624.2 ETO21032.1 - 5.1e-05 22.7 3.1 0.00027 20.4 0.2 2.3 1 1 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF4393 PF14337.1 ETO21032.1 - 0.076 12.4 0.1 0.17 11.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4393) WD40 PF00400.27 ETO21033.1 - 1.4e-32 110.3 12.7 5.7e-10 38.6 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat DEAD PF00270.24 ETO21036.1 - 7.6e-49 165.4 0.0 1.6e-47 161.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETO21036.1 - 2.5e-28 97.7 0.0 1.3e-27 95.4 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETO21036.1 - 0.0031 17.3 0.0 0.0076 16.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Fumble PF03630.9 ETO21037.1 - 6.5e-15 54.8 0.0 9e-15 54.3 0.0 1.1 1 0 0 1 1 1 1 Fumble Fumble PF03630.9 ETO21038.1 - 5.9e-77 258.8 0.0 7.3e-77 258.5 0.0 1.0 1 0 0 1 1 1 1 Fumble zf-C2H2 PF00096.21 ETO21039.1 - 0.00078 19.6 30.9 0.033 14.5 0.5 4.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETO21039.1 - 0.018 15.3 0.4 0.018 15.3 0.2 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETO21039.1 - 0.46 10.8 24.1 0.17 12.2 2.6 4.4 4 0 0 4 4 4 0 Zinc-finger double domain DNA_pol_phi PF04931.8 ETO21039.1 - 0.79 7.4 19.0 1.5 6.5 13.2 1.4 1 0 0 1 1 1 0 DNA polymerase phi CobT PF06213.7 ETO21039.1 - 2.3 7.2 21.3 3.8 6.5 14.7 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.9 ETO21039.1 - 2.9 5.8 12.7 4.4 5.2 8.8 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4064 PF13273.1 ETO21040.1 - 0.22 11.6 1.0 0.8 9.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Pex14_N PF04695.8 ETO21040.1 - 5.7 6.9 16.0 7.6 6.5 0.1 3.8 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Methyltransf_2 PF00891.13 ETO21041.1 - 3.7e-34 117.9 0.0 5.2e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 ETO21041.1 - 0.056 14.0 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_S8 PF00082.17 ETO21043.1 - 1.5e-09 37.4 0.0 2e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Subtilase family zf-TRAF PF02176.13 ETO21044.1 - 1.2e-05 25.5 2.1 1.2e-05 25.5 1.5 2.7 4 0 0 4 4 4 1 TRAF-type zinc finger zf-BED PF02892.10 ETO21044.1 - 0.15 11.8 1.7 4.4 7.1 0.0 3.2 3 0 0 3 3 3 0 BED zinc finger Toxin_1 PF00087.16 ETO21044.1 - 1.7 9.0 10.2 10 6.5 0.1 3.7 3 1 0 3 3 3 0 Snake toxin zf-C3HC4_2 PF13923.1 ETO21044.1 - 1.9 8.6 8.7 0.56 10.2 1.4 3.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CtaG_Cox11 PF04442.9 ETO21045.1 - 5.7e-41 139.8 0.3 2.4e-36 124.8 0.3 2.2 2 0 0 2 2 2 2 Cytochrome c oxidase assembly protein CtaG/Cox11 zf-H2C2_2 PF13465.1 ETO21046.1 - 2.3e-12 46.5 24.4 4.7e-05 23.4 1.1 4.4 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 ETO21046.1 - 9.9e-09 34.9 26.1 0.00015 21.8 0.4 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 ETO21046.1 - 2.5e-08 33.7 28.4 0.0044 17.2 0.5 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 ETO21046.1 - 0.00022 21.0 0.2 0.00022 21.0 0.1 4.4 3 1 1 4 4 4 2 C2H2-type zinc finger MIS13 PF08202.6 ETO21046.1 - 0.025 13.6 0.2 0.029 13.4 0.1 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Zn-ribbon_8 PF09723.5 ETO21046.1 - 0.44 10.5 0.1 0.44 10.5 0.1 3.8 4 0 0 4 4 4 0 Zinc ribbon domain zf-met PF12874.2 ETO21046.1 - 2.1 8.6 15.7 6.7 7.0 1.0 3.8 4 0 0 4 4 4 0 Zinc-finger of C2H2 type DUF2197 PF09963.4 ETO21046.1 - 2.4 8.1 9.8 0.44 10.5 0.3 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-CHY PF05495.7 ETO21046.1 - 2.8 8.1 17.4 0.98 9.6 6.2 2.7 1 1 1 2 2 2 0 CHY zinc finger PDZ PF00595.19 ETO21049.1 - 0.021 14.9 0.0 0.027 14.6 0.0 1.2 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) Taxilin PF09728.4 ETO21051.1 - 0.0084 15.2 0.2 0.011 14.9 0.1 1.2 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF912 PF06024.7 ETO21051.1 - 0.4 10.7 3.9 0.12 12.4 0.3 1.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4234 PF14018.1 ETO21052.1 - 0.065 12.9 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) Ferritin PF00210.19 ETO21053.1 - 0.015 15.0 0.8 0.032 13.9 0.4 1.7 2 0 0 2 2 2 0 Ferritin-like domain zf-RAG1 PF10426.4 ETO21053.1 - 0.056 13.4 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Recombination-activating protein 1 zinc-finger domain CD52 PF15116.1 ETO21053.1 - 0.14 11.9 0.9 0.28 11.0 0.7 1.4 1 0 0 1 1 1 0 CAMPATH-1 antigen LON PF02190.11 ETO21055.1 - 1.4e-11 44.4 1.9 3.6e-11 43.1 0.0 2.2 2 1 0 2 2 2 1 ATP-dependent protease La (LON) domain zf-C3HC4_4 PF15227.1 ETO21055.1 - 0.056 13.3 1.8 0.2 11.5 1.3 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 ETO21055.1 - 0.081 12.9 1.4 0.33 11.0 1.0 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) OTU PF02338.14 ETO21055.1 - 0.081 13.5 1.6 5.1 7.7 0.0 2.5 2 0 0 2 2 2 0 OTU-like cysteine protease Brr6_like_C_C PF10104.4 ETO21055.1 - 0.54 9.7 8.5 0.065 12.7 1.1 2.8 3 0 0 3 3 3 0 Di-sulfide bridge nucleocytoplasmic transport domain Peptidase_S10 PF00450.17 ETO21056.1 - 2.6e-31 109.2 1.6 4.1e-31 108.5 1.1 1.2 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_4 PF08386.5 ETO21056.1 - 0.03 14.2 0.1 0.96 9.3 0.0 2.4 2 0 0 2 2 2 0 TAP-like protein M16C_assoc PF08367.6 ETO21057.1 - 9e-16 57.4 3.6 2.2e-15 56.2 2.5 1.6 1 1 0 1 1 1 1 Peptidase M16C associated Chrome_Resist PF09828.4 ETO21057.1 - 0.12 12.5 0.2 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Chromate resistance exported protein Glyco_transf_92 PF01697.22 ETO21058.1 - 9e-09 35.0 0.7 1.2e-08 34.6 0.5 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.1 ETO21058.1 - 0.0033 17.7 0.0 0.005 17.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 BicD PF09730.4 ETO21060.1 - 0.023 13.0 1.3 0.023 13.0 0.9 1.5 2 0 0 2 2 2 0 Microtubule-associated protein Bicaudal-D DUF4630 PF15443.1 ETO21060.1 - 0.095 12.5 0.6 0.2 11.4 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4630) IBV_3C PF03620.8 ETO21062.1 - 0.044 13.6 0.4 0.044 13.6 0.3 1.9 2 0 0 2 2 2 0 IBV 3C protein DUF3959 PF13105.1 ETO21063.1 - 0.13 11.5 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) DUF1325 PF07039.6 ETO21064.1 - 4.4e-05 23.1 0.0 0.00018 21.0 0.0 2.0 1 0 0 1 1 1 1 SGF29 tudor-like domain Kelch_1 PF01344.20 ETO21065.1 - 0.012 15.1 4.2 4.5 6.9 0.0 4.0 4 0 0 4 4 4 0 Kelch motif Katanin_con80 PF13925.1 ETO21065.1 - 0.044 13.5 0.2 0.081 12.6 0.2 1.3 1 0 0 1 1 1 0 con80 domain of Katanin Kelch_6 PF13964.1 ETO21065.1 - 0.049 13.8 5.5 2.4 8.4 0.0 4.4 4 1 1 5 5 5 0 Kelch motif Kelch_2 PF07646.10 ETO21065.1 - 0.087 12.6 0.1 2.7 7.9 0.0 3.4 4 0 0 4 4 4 0 Kelch motif DUF4355 PF14265.1 ETO21065.1 - 2.1 8.2 13.3 4.1 7.3 9.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) IFRD PF05004.8 ETO21066.1 - 1.4e-10 40.7 0.1 1.4e-10 40.7 0.1 2.5 1 1 1 2 2 1 1 Interferon-related developmental regulator (IFRD) Selenoprotein_S PF06936.6 ETO21066.1 - 0.00018 21.1 0.4 0.00018 21.1 0.3 2.7 3 0 0 3 3 2 1 Selenoprotein S (SelS) Nop14 PF04147.7 ETO21066.1 - 0.0004 18.4 37.0 0.0004 18.4 25.6 2.8 3 0 0 3 3 3 1 Nop14-like family Ycf1 PF05758.7 ETO21066.1 - 0.0099 13.6 22.1 0.028 12.1 8.0 2.3 2 0 0 2 2 2 2 Ycf1 DDHD PF02862.12 ETO21066.1 - 0.022 14.5 24.0 1.1 9.0 0.1 2.3 2 0 0 2 2 2 0 DDHD domain 7tm_1 PF00001.16 ETO21066.1 - 0.058 12.5 1.0 0.13 11.4 0.7 1.5 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Zip PF02535.17 ETO21066.1 - 0.23 10.4 12.0 1.6 7.7 5.7 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter SpoIIIAH PF12685.2 ETO21066.1 - 1 8.8 24.0 22 4.4 0.0 2.6 2 0 0 2 2 2 0 SpoIIIAH-like protein DUF1510 PF07423.6 ETO21066.1 - 1.2 8.4 51.8 0.65 9.3 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) DUF4637 PF15470.1 ETO21066.1 - 2.1 7.9 19.3 0.33 10.5 9.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) SAPS PF04499.10 ETO21066.1 - 8.1 4.9 25.4 6.2e+02 -1.3 17.6 2.1 1 1 0 1 1 1 0 SIT4 phosphatase-associated protein Trypan_PARP PF05887.6 ETO21066.1 - 8.6 6.1 30.3 18 5.1 21.0 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) YMF19 PF02326.10 ETO21066.1 - 9.3 6.9 14.0 0.084 13.4 2.2 3.1 3 1 0 3 3 3 0 Plant ATP synthase F0 Rhabdo_M2 PF04785.7 ETO21067.1 - 0.023 13.7 0.3 0.035 13.1 0.2 1.2 1 0 0 1 1 1 0 Rhabdovirus matrix protein M2 vMSA PF00695.14 ETO21067.1 - 1.3 8.1 4.1 1.6 7.8 2.8 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus FlaG PF03646.10 ETO21067.1 - 2.2 8.4 10.5 4.8 7.3 4.4 2.4 2 1 0 2 2 2 0 FlaG protein Neur_chan_memb PF02932.11 ETO21067.1 - 5.3 6.8 5.4 5.6 6.7 3.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Kinesin PF00225.18 ETO21068.1 - 1.1e-23 83.5 0.1 4.8e-17 61.6 0.0 2.0 1 1 1 2 2 2 2 Kinesin motor domain Myb_Cef PF11831.3 ETO21069.1 - 0.013 14.7 5.1 0.015 14.5 3.5 1.2 1 0 0 1 1 1 0 pre-mRNA splicing factor component RR_TM4-6 PF06459.7 ETO21069.1 - 0.26 11.1 6.8 0.31 10.8 4.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 IncA PF04156.9 ETO21069.1 - 0.89 9.1 3.7 1.1 8.7 2.6 1.1 1 0 0 1 1 1 0 IncA protein CDC45 PF02724.9 ETO21069.1 - 0.98 7.3 5.2 1.2 7.0 3.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Sec62 PF03839.11 ETO21069.1 - 2.7 7.3 5.4 3.8 6.8 3.7 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 PITH PF06201.8 ETO21071.1 - 7.3e-18 64.7 3.0 1.1e-17 64.2 2.1 1.3 1 0 0 1 1 1 1 PITH domain DUF2553 PF10830.3 ETO21072.1 - 0.13 12.7 0.2 2.1 8.9 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2553) PI3_PI4_kinase PF00454.22 ETO21073.1 - 8.1e-09 35.2 1.2 3.5e-08 33.2 0.0 2.3 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase TAF1D PF15333.1 ETO21073.1 - 3.2 7.4 9.3 1.7 8.3 0.2 2.2 2 0 0 2 2 2 0 TATA box-binding protein-associated factor 1D HRDC PF00570.18 ETO21074.1 - 0.0095 15.6 0.1 0.022 14.4 0.1 1.6 1 0 0 1 1 1 1 HRDC domain Orthopox_B11R PF07033.6 ETO21074.1 - 0.2 11.1 4.4 0.37 10.2 1.8 2.3 2 1 0 2 2 2 0 Orthopoxvirus B11R protein NARP1 PF12569.3 ETO21074.1 - 0.89 8.2 7.0 1.1 7.9 4.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Arif-1 PF06770.6 ETO21075.1 - 0.0099 15.2 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 1 Actin-rearrangement-inducing factor (Arif-1) IncA PF04156.9 ETO21076.1 - 0.098 12.2 0.6 15 5.0 0.0 2.5 2 0 0 2 2 2 0 IncA protein PIG-P PF08510.7 ETO21076.1 - 0.38 10.3 0.0 0.38 10.3 0.0 3.3 3 0 0 3 3 3 0 PIG-P DUF4131 PF13567.1 ETO21076.1 - 3.3 7.0 12.8 1.8 7.9 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DUF3278 PF11683.3 ETO21077.1 - 0.0018 18.2 0.8 0.0018 18.2 0.6 1.8 2 1 1 3 3 3 1 Protein of unknown function (DUF3278) Neur_chan_memb PF02932.11 ETO21077.1 - 0.027 14.3 2.7 0.15 11.8 1.9 2.0 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CoA_binding_3 PF13727.1 ETO21077.1 - 0.07 12.9 0.2 0.07 12.9 0.2 1.6 2 0 0 2 2 2 0 CoA-binding domain EF-hand_8 PF13833.1 ETO21078.1 - 7e-06 25.5 4.6 1.4e-05 24.5 3.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 ETO21078.1 - 4.3e-05 23.5 6.8 0.00013 22.0 4.7 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO21078.1 - 0.00025 20.6 5.9 0.39 10.7 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 ETO21078.1 - 0.00033 19.7 8.2 0.12 11.7 2.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_10 PF14788.1 ETO21078.1 - 0.0094 15.5 3.9 0.018 14.7 1.4 2.2 1 1 1 2 2 2 1 EF hand EF-hand_5 PF13202.1 ETO21078.1 - 0.031 13.6 1.1 0.11 11.8 0.1 2.3 2 0 0 2 2 2 0 EF hand Semialdhyde_dh PF01118.19 ETO21078.1 - 0.057 13.7 0.1 0.099 12.9 0.1 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain SPARC_Ca_bdg PF10591.4 ETO21078.1 - 0.14 12.2 6.4 0.027 14.4 1.1 2.2 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region RhoGEF PF00621.15 ETO21078.1 - 2.1 8.2 8.6 20 5.0 5.6 2.4 1 1 0 1 1 1 0 RhoGEF domain PARG_cat PF05028.9 ETO21079.1 - 4.8e-75 252.9 0.9 1.7e-74 251.1 0.6 1.7 1 1 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) Neisseria_TspB PF05616.8 ETO21080.1 - 0.19 10.0 11.9 0.055 11.8 6.4 1.5 2 0 0 2 2 2 0 Neisseria meningitidis TspB protein Herpes_LMP2 PF07415.6 ETO21080.1 - 0.43 9.1 1.7 0.65 8.5 1.2 1.3 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Pex14_N PF04695.8 ETO21080.1 - 0.8 9.7 18.2 0.09 12.8 5.9 2.4 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MDFI PF15316.1 ETO21080.1 - 8.4 6.3 10.7 0.98 9.3 2.6 2.3 2 0 0 2 2 2 0 MyoD family inhibitor CENP-B_dimeris PF09026.5 ETO21081.1 - 0.0036 17.4 4.2 0.012 15.7 1.2 2.5 3 0 0 3 3 3 1 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 ETO21081.1 - 0.11 12.0 3.9 0.19 11.2 2.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 ETO21081.1 - 0.28 11.5 5.0 0.52 10.6 3.5 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UBA PF00627.26 ETO21083.1 - 4.7e-09 35.8 1.5 0.00031 20.4 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.6 ETO21083.1 - 6.8e-07 28.6 4.7 1.6e-06 27.4 3.3 1.7 1 0 0 1 1 1 1 XPC-binding domain Ycf1 PF05758.7 ETO21083.1 - 0.3 8.7 5.5 0.43 8.2 3.8 1.2 1 0 0 1 1 1 0 Ycf1 DUF1754 PF08555.5 ETO21083.1 - 4.6 7.8 22.0 1.6 9.3 10.3 2.5 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) DUF2464 PF10240.4 ETO21083.1 - 4.9 6.4 0.0 4.9 6.4 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2464) CCDC92 PF14916.1 ETO21084.1 - 0.0078 15.7 0.2 0.0078 15.7 0.1 4.3 5 1 0 5 5 5 1 Coiled-coil domain of unknown function MAAL_C PF07476.6 ETO21084.1 - 0.031 13.2 2.2 0.054 12.4 1.4 1.5 1 1 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Reo_sigmaC PF04582.7 ETO21084.1 - 0.061 12.4 13.7 0.023 13.9 5.2 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Mto2_bdg PF12808.2 ETO21084.1 - 0.5 10.5 11.9 9.5 6.4 0.5 4.5 3 1 1 4 4 4 0 Micro-tubular organiser Mto1 C-term Mto2-binding region ABC1 PF03109.11 ETO21084.1 - 0.67 9.9 6.0 1.8 8.5 0.1 2.6 1 1 0 2 2 2 0 ABC1 family DUF3540 PF12059.3 ETO21084.1 - 0.7 9.4 8.2 0.19 11.3 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3540) DHquinase_II PF01220.14 ETO21084.1 - 1 8.6 5.2 0.61 9.3 1.4 2.1 1 1 1 2 2 2 0 Dehydroquinase class II Taxilin PF09728.4 ETO21084.1 - 1.1 8.3 38.0 0.012 14.7 11.2 2.1 1 1 1 2 2 2 0 Myosin-like coiled-coil protein ERM PF00769.14 ETO21084.1 - 1.2 8.6 34.8 0.52 9.7 11.0 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family GAS PF13851.1 ETO21084.1 - 1.5 7.9 34.8 0.027 13.6 17.1 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 ETO21084.1 - 1.9 8.8 30.0 0.66 10.3 2.0 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF972) Tweety PF04906.8 ETO21084.1 - 1.9 6.8 13.3 0.26 9.6 5.9 1.8 1 1 0 2 2 2 0 Tweety Myosin_tail_1 PF01576.14 ETO21084.1 - 2.1 5.9 36.3 6.8 4.2 25.1 1.7 1 1 0 1 1 1 0 Myosin tail DUF3166 PF11365.3 ETO21084.1 - 2.9 8.4 15.4 1.2 9.6 2.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3166) DUF3708 PF12501.3 ETO21084.1 - 3.6 7.4 8.7 0.29 10.9 0.9 2.1 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter CENP-F_leu_zip PF10473.4 ETO21085.1 - 2.1e-07 30.8 63.2 0.0026 17.6 11.1 4.3 1 1 3 4 4 4 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 ETO21085.1 - 0.00022 20.8 62.6 0.0042 16.7 8.7 4.1 1 1 3 4 4 4 2 IncA protein IFT57 PF10498.4 ETO21085.1 - 0.00029 19.6 51.4 0.015 14.0 6.3 3.1 1 1 2 3 3 3 2 Intra-flagellar transport protein 57 Reo_sigmaC PF04582.7 ETO21085.1 - 0.0011 18.2 15.6 0.016 14.4 1.8 3.0 1 1 2 3 3 3 2 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 ETO21085.1 - 0.0013 16.6 62.0 0.013 13.2 26.9 2.8 1 1 2 3 3 3 3 Myosin tail Filament PF00038.16 ETO21085.1 - 0.0019 17.7 57.2 0.0023 17.4 30.7 2.8 1 1 0 2 2 2 1 Intermediate filament protein ADIP PF11559.3 ETO21085.1 - 0.0023 17.8 61.7 0.051 13.4 8.1 4.2 1 1 2 4 4 4 2 Afadin- and alpha -actinin-Binding GAS PF13851.1 ETO21085.1 - 0.0041 16.3 63.0 0.027 13.6 15.9 3.2 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding DUF2968 PF11180.3 ETO21085.1 - 0.0074 15.6 47.9 0.05 12.9 5.1 4.3 1 1 3 4 4 4 2 Protein of unknown function (DUF2968) Ax_dynein_light PF10211.4 ETO21085.1 - 0.0078 16.0 7.7 0.0078 16.0 5.4 4.6 1 1 4 5 5 5 1 Axonemal dynein light chain Baculo_PEP_C PF04513.7 ETO21085.1 - 0.01 15.6 31.0 2 8.2 1.1 4.9 2 2 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.7 ETO21085.1 - 0.011 15.4 43.2 0.75 9.5 6.2 4.5 1 1 4 5 5 5 0 Laminin Domain II Rab5-bind PF09311.6 ETO21085.1 - 0.021 14.7 4.3 0.021 14.7 3.0 3.6 1 1 1 3 3 3 0 Rabaptin-like protein AAA_13 PF13166.1 ETO21085.1 - 0.026 12.9 49.6 0.49 8.8 22.3 2.7 1 1 2 3 3 3 0 AAA domain HrpB7 PF09486.5 ETO21085.1 - 0.028 14.3 0.4 0.028 14.3 0.3 4.0 1 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB7) Seryl_tRNA_N PF02403.17 ETO21085.1 - 0.031 14.2 55.4 0.12 12.4 4.6 4.4 2 2 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DUF972 PF06156.8 ETO21085.1 - 0.033 14.5 51.6 0.36 11.2 5.2 5.1 1 1 4 5 5 5 0 Protein of unknown function (DUF972) APG6 PF04111.7 ETO21085.1 - 0.056 12.4 62.3 0.2 10.6 6.7 3.0 1 1 2 3 3 3 0 Autophagy protein Apg6 ATG16 PF08614.6 ETO21085.1 - 0.059 13.1 62.7 0.21 11.4 8.1 4.1 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) WEMBL PF05701.6 ETO21085.1 - 0.071 11.5 52.1 0.039 12.4 22.0 2.3 1 1 1 2 2 2 0 Weak chloroplast movement under blue light DUF3584 PF12128.3 ETO21085.1 - 0.082 10.2 53.9 0.035 11.4 26.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.7 ETO21085.1 - 0.094 12.4 58.4 0.11 12.1 13.5 3.8 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.6 ETO21085.1 - 0.13 10.9 57.6 0.78 8.3 17.3 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein EzrA PF06160.7 ETO21085.1 - 0.21 9.7 50.1 0.63 8.1 22.3 2.6 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF869 PF05911.6 ETO21085.1 - 0.23 9.6 51.1 0.037 12.2 15.5 2.6 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) ERM PF00769.14 ETO21085.1 - 0.33 10.4 56.2 1.1 8.7 13.7 3.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Mnd1 PF03962.10 ETO21085.1 - 0.33 10.5 58.0 0.27 10.9 7.9 3.8 1 1 4 5 5 5 0 Mnd1 family DUF342 PF03961.8 ETO21085.1 - 0.38 9.1 51.1 0.046 12.1 7.6 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF342) DUF4201 PF13870.1 ETO21085.1 - 0.47 9.8 60.8 0.31 10.4 13.9 4.1 1 1 1 3 3 3 0 Domain of unknown function (DUF4201) Laminin_I PF06008.9 ETO21085.1 - 0.52 9.5 46.8 0.051 12.8 9.1 3.3 1 1 2 3 3 3 0 Laminin Domain I TMF_DNA_bd PF12329.3 ETO21085.1 - 0.69 9.7 67.9 0.46 10.3 11.2 5.9 2 2 3 5 5 5 0 TATA element modulatory factor 1 DNA binding MscS_porin PF12795.2 ETO21085.1 - 0.91 8.7 48.3 1.9 7.7 10.9 3.4 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain Tropomyosin_1 PF12718.2 ETO21085.1 - 1.2 9.0 69.5 0.14 11.9 14.0 4.1 1 1 2 4 4 4 0 Tropomyosin like DUF1664 PF07889.7 ETO21085.1 - 1.2 8.8 39.0 0.6 9.9 5.2 4.8 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.1 ETO21085.1 - 1.3 9.3 46.4 0.52 10.6 9.1 4.9 2 1 3 5 5 5 0 Snapin/Pallidin TBPIP PF07106.8 ETO21085.1 - 1.4 8.4 59.8 0.98 8.9 3.2 4.6 1 1 3 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF948 PF06103.6 ETO21085.1 - 1.8 8.4 36.5 0.038 13.8 2.0 5.0 2 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DivIC PF04977.10 ETO21085.1 - 1.8 8.0 61.0 1.1 8.7 2.8 6.9 2 2 5 7 7 7 0 Septum formation initiator CALCOCO1 PF07888.6 ETO21085.1 - 2.4 6.3 52.3 0.17 10.1 17.9 2.2 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Atg14 PF10186.4 ETO21085.1 - 2.4 7.0 56.9 2.5 6.9 9.5 3.1 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Taxilin PF09728.4 ETO21085.1 - 2.9 6.9 58.1 0.77 8.7 13.0 3.2 1 1 2 3 3 3 0 Myosin-like coiled-coil protein RuvC PF02075.12 ETO21085.1 - 3.7 7.3 5.1 4.7 7.0 0.2 3.2 2 1 0 4 4 3 0 Crossover junction endodeoxyribonuclease RuvC TMF_TATA_bd PF12325.3 ETO21085.1 - 4.5 7.0 60.1 2 8.1 6.0 4.5 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding Fib_alpha PF08702.5 ETO21085.1 - 4.8 7.3 47.6 2.1 8.4 5.9 4.7 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family DUF4618 PF15397.1 ETO21085.1 - 5.4 6.2 54.1 0.2 10.9 10.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) CCDC155 PF14662.1 ETO21085.1 - 6.7 6.2 56.5 7.9 6.0 5.6 3.0 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 Cluap1 PF10234.4 ETO21085.1 - 7.3 5.6 49.2 0.69 9.0 11.7 3.1 1 1 2 3 3 3 0 Clusterin-associated protein-1 Cast PF10174.4 ETO21085.1 - 7.6 4.4 61.3 82 1.0 42.6 2.2 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DUF3037 PF11236.3 ETO21085.1 - 9.6 6.2 9.2 4.2 7.4 0.4 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF3037) Kelch_1 PF01344.20 ETO21086.1 - 1.9e-05 24.1 0.4 0.041 13.4 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO21086.1 - 0.0035 17.4 0.0 1.9 8.7 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 ETO21086.1 - 0.019 15.1 1.0 3 8.1 0.0 3.6 4 0 0 4 4 4 0 Galactose oxidase, central domain DUF3172 PF11371.3 ETO21086.1 - 0.024 14.1 0.8 0.064 12.7 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3172) KduI PF04962.7 ETO21086.1 - 0.037 13.0 0.5 0.067 12.2 0.4 1.3 1 0 0 1 1 1 0 KduI/IolB family Kelch_4 PF13418.1 ETO21086.1 - 0.097 12.4 0.1 14 5.5 0.0 3.0 3 0 0 3 3 3 0 Galactose oxidase, central domain DUF2122 PF09895.4 ETO21086.1 - 0.14 12.3 0.2 0.35 11.0 0.1 1.6 1 0 0 1 1 1 0 RecB-family nuclease (DUF2122) TFIIE-A_C-term PF11521.3 ETO21086.1 - 0.77 9.7 6.0 1.6 8.7 0.2 2.9 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha Med8 PF10232.4 ETO21088.1 - 1.4 8.3 15.1 0.79 9.1 8.3 1.9 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 OTU PF02338.14 ETO21090.1 - 2.7e-05 24.7 0.6 6.8e-05 23.4 0.1 2.0 2 0 0 2 2 2 1 OTU-like cysteine protease MBT PF02820.13 ETO21090.1 - 0.0013 18.6 0.7 0.34 10.8 0.0 2.8 3 0 0 3 3 3 2 mbt repeat Agenet PF05641.7 ETO21090.1 - 0.03 14.4 1.4 0.35 11.0 0.1 2.5 2 0 0 2 2 2 0 Agenet domain Tudor-knot PF11717.3 ETO21090.1 - 6.5 6.5 7.4 4.9 6.9 0.3 3.4 3 1 0 3 3 3 0 RNA binding activity-knot of a chromodomain VID27 PF08553.5 ETO21092.1 - 0.0017 16.7 6.3 0.0022 16.3 4.4 1.1 1 0 0 1 1 1 1 VID27 cytoplasmic protein Nop14 PF04147.7 ETO21092.1 - 0.0096 13.9 6.8 0.012 13.5 4.7 1.2 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 ETO21092.1 - 0.012 14.0 5.7 0.017 13.6 3.9 1.2 1 0 0 1 1 1 0 Daxx Family Sigma70_ner PF04546.8 ETO21092.1 - 0.13 11.9 7.2 0.26 10.8 5.0 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.4 ETO21092.1 - 0.43 9.2 22.3 0.7 8.5 15.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sporozoite_P67 PF05642.6 ETO21092.1 - 1.5 6.6 4.8 2.1 6.1 3.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MIT PF04212.13 ETO21093.1 - 0.21 11.4 5.2 1.8 8.4 1.0 2.6 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Zip PF02535.17 ETO21093.1 - 0.38 9.7 0.8 1 8.2 0.1 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter FlgN PF05130.7 ETO21093.1 - 0.78 9.9 13.9 0.11 12.6 6.7 1.8 2 0 0 2 2 2 0 FlgN protein WD40 PF00400.27 ETO21094.1 - 2.1e-22 78.0 2.2 2.8e-07 30.1 0.0 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO21094.1 - 4.6e-06 25.6 3.0 2e-05 23.5 2.0 1.9 1 1 0 1 1 1 1 Nup133 N terminal like BBS2_Mid PF14783.1 ETO21094.1 - 0.0016 18.1 0.0 5.3 6.8 0.0 3.4 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.1 ETO21094.1 - 0.04 13.3 0.0 4.1 6.8 0.0 2.8 3 0 0 3 3 3 0 PQQ-like domain WD40 PF00400.27 ETO21095.1 - 1.3e-28 97.7 3.3 8e-13 47.7 0.2 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat DPPIV_N PF00930.16 ETO21095.1 - 0.024 13.2 0.0 6.4 5.2 0.0 2.6 3 0 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Speriolin_C PF15059.1 ETO21095.1 - 0.083 12.9 0.0 85 3.1 0.1 3.2 3 0 0 3 3 3 0 Speriolin C-terminus Pkinase PF00069.20 ETO21097.1 - 1.6e-18 66.8 0.0 2.2e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO21097.1 - 4.4e-13 48.9 0.0 9.4e-13 47.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO21097.1 - 0.00086 18.3 0.1 0.0016 17.4 0.0 1.4 2 0 0 2 2 2 1 Kinase-like Init_tRNA_PT PF04179.7 ETO21098.1 - 7.4e-86 288.7 5.2 9.1e-86 288.4 3.6 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase YflT PF11181.3 ETO21099.1 - 0.2 11.7 0.0 0.2 11.7 0.0 2.6 3 1 0 3 3 3 0 Heat induced stress protein YflT ANAPC15 PF15243.1 ETO21099.1 - 2.3 8.3 8.4 3.3 7.8 4.4 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 15 YfhO PF09586.5 ETO21101.1 - 0.23 9.4 2.5 0.3 9.0 1.7 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Spore_YhcN_YlaJ PF09580.5 ETO21102.1 - 0.64 10.1 16.3 0.77 9.8 11.3 1.2 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF3984 PF13136.1 ETO21102.1 - 1.3 8.1 8.5 1.5 7.9 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) NOA36 PF06524.7 ETO21102.1 - 1.4 8.1 8.1 1.3 8.1 5.6 1.1 1 0 0 1 1 1 0 NOA36 protein CWC25 PF12542.3 ETO21102.1 - 1.5 9.3 12.2 0.85 10.1 7.2 1.6 2 0 0 2 2 2 0 Pre-mRNA splicing factor FLO_LFY PF01698.11 ETO21102.1 - 3.2 6.4 8.2 3.6 6.3 5.7 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Menin PF05053.8 ETO21102.1 - 3.4 5.7 11.2 3.4 5.7 7.8 1.2 1 0 0 1 1 1 0 Menin Pox_Ag35 PF03286.9 ETO21102.1 - 4.7 6.6 10.1 5.9 6.3 7.0 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein EF-hand_7 PF13499.1 ETO21104.1 - 0.013 15.6 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.1 ETO21104.1 - 0.03 13.9 0.0 0.098 12.2 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.27 ETO21104.1 - 0.11 11.8 0.1 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 EF hand PA PF02225.17 ETO21105.1 - 9.3e-06 25.2 0.2 2.2e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 PA domain DUF3357 PF11837.3 ETO21105.1 - 0.017 15.0 0.0 0.052 13.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) ERG4_ERG24 PF01222.12 ETO21105.1 - 0.024 13.1 0.6 0.037 12.5 0.4 1.2 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family Tetraspannin PF00335.15 ETO21105.1 - 0.026 13.8 0.2 0.79 8.9 0.0 2.1 2 0 0 2 2 2 0 Tetraspanin family Sigma_reg_N PF13800.1 ETO21105.1 - 0.032 14.2 1.0 1 9.4 0.0 2.3 2 0 0 2 2 2 0 Sigma factor regulator N-terminal ETRAMP PF09716.5 ETO21105.1 - 0.12 12.3 3.1 3.1 7.8 0.6 2.4 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF2633 PF11119.3 ETO21105.1 - 0.2 11.3 3.0 0.53 10.0 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) ATP-synt_8 PF00895.15 ETO21105.1 - 1.3 9.3 3.9 1.6 8.9 1.5 2.0 2 0 0 2 2 2 0 ATP synthase protein 8 zf-TRAF PF02176.13 ETO21108.1 - 0.0012 19.1 2.8 0.0012 19.1 1.9 3.4 3 0 0 3 3 3 1 TRAF-type zinc finger CENP-F_leu_zip PF10473.4 ETO21108.1 - 0.0056 16.5 15.3 0.011 15.5 10.6 1.5 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-C3HC4_2 PF13923.1 ETO21108.1 - 0.011 15.7 3.4 0.031 14.3 2.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DivIVA PF05103.8 ETO21108.1 - 0.017 15.1 8.7 0.037 14.0 6.1 1.5 1 0 0 1 1 1 0 DivIVA protein S4 PF01479.20 ETO21108.1 - 0.036 13.5 0.0 0.078 12.4 0.0 1.5 1 0 0 1 1 1 0 S4 domain TMF_TATA_bd PF12325.3 ETO21108.1 - 0.09 12.5 16.1 0.17 11.6 11.2 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 ETO21108.1 - 0.15 11.6 15.6 0.25 10.8 10.8 1.3 1 0 0 1 1 1 0 IncA protein Herpes_BLRF2 PF05812.7 ETO21108.1 - 0.17 11.6 8.7 0.34 10.7 6.0 1.5 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein DUF2968 PF11180.3 ETO21108.1 - 0.36 10.1 7.9 0.64 9.3 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF948 PF06103.6 ETO21108.1 - 0.38 10.6 4.0 1 9.2 2.7 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Reo_sigmaC PF04582.7 ETO21108.1 - 0.41 9.7 1.1 0.63 9.1 0.8 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein FlxA PF14282.1 ETO21108.1 - 2.1 8.3 15.6 4.5 7.2 10.8 1.6 1 0 0 1 1 1 0 FlxA-like protein DivIC PF04977.10 ETO21108.1 - 8.4 5.9 10.7 2.1 7.9 1.0 2.5 1 1 1 2 2 2 0 Septum formation initiator PDEase_I PF00233.14 ETO21109.1 - 1.1e-64 218.4 0.1 1.5e-64 217.9 0.1 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase CDC45 PF02724.9 ETO21109.1 - 0.093 10.7 30.7 0.31 9.0 12.6 2.4 2 0 0 2 2 2 0 CDC45-like protein MIP-T3 PF10243.4 ETO21109.1 - 0.49 8.8 26.3 0.75 8.1 18.2 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Vfa1 PF08432.5 ETO21109.1 - 1.5 8.8 32.8 0.42 10.6 2.4 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Pox_RNA_Pol_19 PF05320.7 ETO21109.1 - 4.9 6.8 25.8 0.93 9.2 9.3 2.4 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Vps51 PF08700.6 ETO21110.1 - 7.9e-08 32.0 3.0 2.2e-07 30.6 2.1 1.8 1 0 0 1 1 1 1 Vps51/Vps67 SSP160 PF06933.6 ETO21110.1 - 8.7e-05 20.7 16.9 8.7e-05 20.7 11.7 1.7 2 0 0 2 2 2 1 Special lobe-specific silk protein SSP160 COG2 PF06148.6 ETO21110.1 - 0.00039 20.2 1.3 0.001 18.9 0.5 2.1 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Enkurin PF13864.1 ETO21110.1 - 0.0098 16.0 4.3 0.49 10.6 0.5 2.5 2 0 0 2 2 2 2 Calmodulin-binding DUF3439 PF11921.3 ETO21110.1 - 0.034 13.9 13.9 0.077 12.7 9.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) FlaC_arch PF05377.6 ETO21110.1 - 0.045 13.6 1.7 0.17 11.8 1.2 2.0 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) PPR PF01535.15 ETO21110.1 - 0.073 13.0 0.1 12 6.1 0.2 3.3 3 0 0 3 3 3 0 PPR repeat Mucin PF01456.12 ETO21110.1 - 0.5 10.1 29.4 0.097 12.4 15.3 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein PAH PF02671.16 ETO21111.1 - 0.055 13.0 0.1 0.22 11.1 0.0 2.2 2 0 0 2 2 2 0 Paired amphipathic helix repeat Peptidase_M50B PF13398.1 ETO21111.1 - 0.12 11.7 0.1 0.2 11.0 0.1 1.2 1 0 0 1 1 1 0 Peptidase M50B-like DUF2714 PF10896.3 ETO21111.1 - 2.7 7.8 10.1 0.19 11.5 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2714) Isochorismatase PF00857.15 ETO21112.1 - 2.8e-18 66.4 0.1 1.7e-17 63.8 0.0 1.9 1 1 0 1 1 1 1 Isochorismatase family NYD-SP28_assoc PF14775.1 ETO21113.1 - 0.027 14.1 6.1 0.043 13.5 4.2 1.4 1 0 0 1 1 1 0 Sperm tail C-terminal domain DUF641 PF04859.7 ETO21113.1 - 0.035 13.8 6.2 0.042 13.6 4.3 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) HrpB7 PF09486.5 ETO21113.1 - 0.092 12.6 2.3 0.1 12.5 1.6 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) APG6 PF04111.7 ETO21113.1 - 0.12 11.4 8.8 0.13 11.3 6.1 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DapH_N PF08503.5 ETO21113.1 - 0.12 12.4 1.0 0.26 11.4 0.7 1.6 1 1 0 1 1 1 0 Tetrahydrodipicolinate succinyltransferase N-terminal CortBP2 PF09727.4 ETO21113.1 - 0.13 11.7 11.1 0.27 10.7 7.7 1.5 1 1 0 1 1 1 0 Cortactin-binding protein-2 DUF2400 PF09674.5 ETO21113.1 - 0.14 11.8 3.1 0.14 11.8 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) ASD2 PF08687.6 ETO21113.1 - 0.18 11.1 6.2 0.27 10.4 4.2 1.5 1 1 0 1 1 1 0 Apx/Shroom domain ASD2 CENP-Q PF13094.1 ETO21113.1 - 0.19 11.7 9.7 0.22 11.5 6.8 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Dfp1_Him1_M PF08630.5 ETO21113.1 - 0.22 11.2 3.1 0.25 11.1 2.1 1.1 1 0 0 1 1 1 0 Dfp1/Him1, central region IncA PF04156.9 ETO21113.1 - 0.23 11.0 13.8 0.27 10.7 9.6 1.0 1 0 0 1 1 1 0 IncA protein Spc24 PF08286.6 ETO21113.1 - 0.45 10.2 9.2 0.57 9.8 6.4 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 FlgN PF05130.7 ETO21113.1 - 0.46 10.7 11.5 0.62 10.3 8.0 1.2 1 0 0 1 1 1 0 FlgN protein DUF3450 PF11932.3 ETO21113.1 - 0.47 9.6 11.9 1.2 8.3 8.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF342 PF03961.8 ETO21113.1 - 0.57 8.5 9.9 0.6 8.4 6.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) ADIP PF11559.3 ETO21113.1 - 0.57 10.0 13.1 0.7 9.7 9.1 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding M_domain PF12938.2 ETO21113.1 - 1.8 8.3 11.5 2.1 8.0 8.0 1.2 1 0 0 1 1 1 0 M domain of GW182 PHTB1_C PF14728.1 ETO21113.1 - 3 6.5 9.0 3.4 6.3 6.2 1.0 1 0 0 1 1 1 0 PTHB1 C-terminus Phage_GP20 PF06810.6 ETO21113.1 - 4.1 6.8 15.4 4 6.8 3.7 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 Calici_MSP PF05752.6 ETO21113.1 - 4.8 6.7 8.0 5.2 6.6 5.5 1.2 1 0 0 1 1 1 0 Calicivirus minor structural protein DUF3373 PF11853.3 ETO21113.1 - 5.9 5.3 7.0 6 5.2 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF2968 PF11180.3 ETO21113.1 - 9.6 5.5 12.9 12 5.2 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DEK_C PF08766.6 ETO21114.1 - 0.00039 20.1 0.0 0.00085 19.0 0.0 1.5 1 0 0 1 1 1 1 DEK C terminal domain DUF1189 PF06691.6 ETO21114.1 - 0.073 12.3 0.1 0.073 12.3 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1189) DUF966 PF06136.8 ETO21114.1 - 2.1 7.6 14.8 3 7.1 10.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) FAM219A PF15260.1 ETO21114.1 - 2.6 8.4 7.6 0.59 10.4 2.4 2.0 2 0 0 2 2 2 0 Protein family FAM219A DUF2431 PF10354.4 ETO21115.1 - 1.4e-09 38.1 1.0 5.1e-09 36.2 0.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF2431) DUF912 PF06024.7 ETO21115.1 - 0.059 13.4 2.6 0.13 12.3 1.8 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Eapp_C PF10238.4 ETO21115.1 - 0.45 10.4 12.2 0.1 12.5 5.7 1.8 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF2956 PF11169.3 ETO21115.1 - 0.66 9.9 8.2 0.17 11.8 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Secretin_N_2 PF07655.8 ETO21115.1 - 1.2 9.5 15.0 3.3 8.1 10.4 1.7 1 0 0 1 1 1 0 Secretin N-terminal domain DUF2183 PF09949.4 ETO21116.1 - 0.11 12.3 1.0 0.33 10.8 0.6 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) VPS11_C PF12451.3 ETO21116.1 - 2.1 8.2 5.9 7 6.5 0.0 3.6 3 0 0 3 3 3 0 Vacuolar protein sorting protein 11 C terminal NicO PF03824.11 ETO21117.1 - 3.4 6.9 6.1 5.2 6.3 4.2 1.4 1 0 0 1 1 1 0 High-affinity nickel-transport protein Zip PF02535.17 ETO21117.1 - 8 5.3 19.0 17 4.2 13.1 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Endonuc_subdom PF09062.5 ETO21118.1 - 3.9 8.2 7.0 43 4.9 0.1 3.5 3 0 0 3 3 3 0 PI-PfuI Endonuclease subdomain PWWP PF00855.12 ETO21120.1 - 0.13 12.4 2.0 0.2 11.8 0.4 1.8 1 1 1 2 2 2 0 PWWP domain DUF4131 PF13567.1 ETO21120.1 - 0.94 8.8 4.4 1.1 8.6 3.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) EF-hand_1 PF00036.27 ETO21121.1 - 1.3e-07 30.3 0.1 4e-07 28.8 0.1 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 ETO21121.1 - 4.8e-06 26.0 0.2 2.1e-05 23.9 0.1 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 ETO21121.1 - 3.5e-05 22.9 0.1 0.0001 21.4 0.1 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 ETO21121.1 - 0.00015 21.8 0.4 0.00015 21.8 0.3 2.3 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 ETO21121.1 - 0.0029 17.1 0.1 0.013 15.0 0.1 2.1 1 1 1 2 2 2 1 EF-hand domain pair Tropomyosin_1 PF12718.2 ETO21121.1 - 2.3 8.0 36.8 1.7 8.4 19.3 2.3 1 1 1 2 2 2 0 Tropomyosin like Rootletin PF15035.1 ETO21121.1 - 2.6 7.9 30.6 4.9e+02 0.5 21.0 2.4 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF3450 PF11932.3 ETO21121.1 - 4 6.6 22.8 0.29 10.3 5.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) DUF912 PF06024.7 ETO21122.1 - 0.0039 17.2 1.9 0.008 16.2 1.3 1.5 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Vezatin PF12632.2 ETO21122.1 - 0.0052 15.9 0.2 0.0091 15.1 0.1 1.3 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes Apc15p PF05841.6 ETO21122.1 - 0.12 13.1 5.4 0.24 12.1 3.8 1.5 1 0 0 1 1 1 0 Apc15p protein DUF2457 PF10446.4 ETO21122.1 - 6 5.4 7.2 8.7 4.9 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Claudin_2 PF13903.1 ETO21123.1 - 0.0018 18.0 3.9 0.0018 18.0 2.7 3.4 2 2 1 3 3 3 1 PMP-22/EMP/MP20/Claudin tight junction FPN1 PF06963.7 ETO21123.1 - 0.88 7.8 11.6 0.16 10.3 1.3 2.9 2 1 0 2 2 2 0 Ferroportin1 (FPN1) Otopetrin PF03189.8 ETO21123.1 - 1.2 8.0 7.8 11 4.9 3.6 2.3 2 1 0 2 2 2 0 Otopetrin Sec62 PF03839.11 ETO21123.1 - 7.4 5.9 13.7 1 8.7 0.5 2.4 2 0 0 2 2 2 0 Translocation protein Sec62 CH PF00307.26 ETO21124.1 - 1.8e-10 40.8 0.0 1.8e-08 34.4 0.0 2.1 2 0 0 2 2 2 2 Calponin homology (CH) domain CH PF00307.26 ETO21125.1 - 4.8e-15 55.5 4.0 1.9e-09 37.5 0.2 3.5 4 0 0 4 4 4 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 ETO21125.1 - 1e-06 28.2 1.4 4.2e-05 23.1 0.1 3.2 3 0 0 3 3 3 1 CAMSAP CH domain VIT1 PF01988.14 ETO21127.1 - 2e-27 96.0 0.4 2e-27 96.0 0.3 1.4 1 1 0 1 1 1 1 VIT family DUF2951 PF11166.3 ETO21128.1 - 9.1 6.2 9.4 5.6 6.8 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) DUF912 PF06024.7 ETO21129.1 - 0.009 16.0 0.5 0.018 15.0 0.3 1.5 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3753 PF12575.3 ETO21129.1 - 0.0094 15.7 5.7 0.024 14.4 3.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3753) SecE PF00584.15 ETO21129.1 - 0.027 14.0 7.8 0.05 13.1 5.4 1.4 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex DUF788 PF05620.6 ETO21129.1 - 0.033 14.0 3.1 0.057 13.2 1.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF788) DUF2116 PF09889.4 ETO21129.1 - 0.051 13.3 0.7 0.16 11.8 0.5 1.8 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) ODV-E18 PF10717.4 ETO21129.1 - 0.068 12.6 0.2 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 zf-C2H2 PF00096.21 ETO21129.1 - 0.19 12.1 0.1 0.19 12.1 0.1 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-AN1 PF01428.11 ETO21129.1 - 0.32 10.8 3.8 2.7 7.9 0.3 2.4 2 0 0 2 2 2 0 AN1-like Zinc finger Synaptobrevin PF00957.16 ETO21129.1 - 1.1 8.9 3.5 0.45 10.1 0.6 1.7 2 0 0 2 2 2 0 Synaptobrevin WH1 PF00568.18 ETO21130.1 - 1.1e-11 44.4 1.1 1.5e-11 43.9 0.4 1.5 1 1 0 1 1 1 1 WH1 domain NMT1 PF09084.6 ETO21130.1 - 0.018 14.6 0.2 0.02 14.5 0.1 1.1 1 0 0 1 1 1 0 NMT1/THI5 like DUF1987 PF09345.5 ETO21130.1 - 0.025 14.3 0.8 0.071 12.9 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) SeqA PF03925.8 ETO21130.1 - 0.11 12.1 8.4 0.14 11.8 5.8 1.2 1 0 0 1 1 1 0 SeqA protein DUF1985 PF09331.6 ETO21130.1 - 0.52 10.1 8.0 0.11 12.3 3.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1985) Tox-REase-5 PF15648.1 ETO21130.1 - 0.65 10.3 4.6 0.28 11.4 1.0 1.9 1 1 1 2 2 2 0 Restriction endonuclease fold toxin 5 DSPn PF14671.1 ETO21130.1 - 0.88 9.5 6.2 0.14 12.1 1.0 1.9 1 1 1 2 2 2 0 Dual specificity protein phosphatase, N-terminal half CWC25 PF12542.3 ETO21130.1 - 2.6 8.5 12.6 1.1 9.8 5.6 2.2 2 1 0 2 2 2 0 Pre-mRNA splicing factor MACPF PF01823.14 ETO21131.1 - 0.41 10.2 8.3 0.03 14.0 1.7 2.0 2 0 0 2 2 2 0 MAC/Perforin domain Apis_Csd PF11671.3 ETO21131.1 - 4.9 6.9 10.7 0.82 9.4 2.4 2.5 2 0 0 2 2 2 0 Complementary sex determiner protein Exonuc_VII_L PF02601.10 ETO21133.1 - 0.047 12.8 8.9 0.058 12.5 6.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.14 ETO21133.1 - 0.52 8.0 8.4 0.6 7.8 5.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Asp-B-Hydro_N PF05279.6 ETO21133.1 - 2.4 7.9 14.0 3.2 7.5 9.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Mitofilin PF09731.4 ETO21133.1 - 3.8 6.0 27.5 5.7 5.4 19.1 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein GpcrRhopsn4 PF10192.4 ETO21133.1 - 3.9 6.6 8.1 5.4 6.1 5.6 1.3 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain APG6 PF04111.7 ETO21133.1 - 6.9 5.6 21.6 11 4.9 15.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 ETO21133.1 - 8.3 5.2 19.3 11 4.7 13.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 UBA PF00627.26 ETO21134.1 - 0.0051 16.6 0.3 0.012 15.4 0.2 1.6 1 0 0 1 1 1 1 UBA/TS-N domain LcrG PF07216.7 ETO21134.1 - 0.047 13.7 0.0 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 LcrG protein HTH_8 PF02954.14 ETO21134.1 - 0.097 12.2 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family 2OG-FeII_Oxy_2 PF13532.1 ETO21136.1 - 2.7e-17 63.2 0.1 3.5e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily tRNA_deacylase PF04414.7 ETO21136.1 - 0.09 11.8 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 D-aminoacyl-tRNA deacylase VPS9 PF02204.13 ETO21137.1 - 4.8e-14 52.2 0.1 7.1e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF1360 PF07098.6 ETO21138.1 - 0.045 13.4 0.3 3.6 7.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1360) FAD_binding_5 PF00941.16 ETO21138.1 - 0.051 13.0 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain in molybdopterin dehydrogenase DNA_pol_phi PF04931.8 ETO21138.1 - 0.22 9.2 10.5 0.39 8.4 6.9 1.8 1 1 0 1 1 1 0 DNA polymerase phi WD40 PF00400.27 ETO21139.1 - 3.8e-55 181.9 5.0 1.4e-12 46.9 0.0 5.0 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 ETO21139.1 - 4.9e-11 42.6 0.7 2.6e-06 27.2 0.0 2.2 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO21139.1 - 2.5e-07 29.2 0.8 0.01 14.0 0.0 3.2 1 1 3 4 4 4 2 Nucleoporin Nup120/160 PD40 PF07676.7 ETO21139.1 - 1.4e-05 24.6 1.9 1.4 8.6 0.1 3.8 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO21139.1 - 0.00075 18.3 1.2 1.7 7.3 0.0 3.3 1 1 2 3 3 3 2 Nup133 N terminal like Ricin_B_lectin PF00652.17 ETO21139.1 - 0.0012 18.8 1.1 0.026 14.5 0.3 2.3 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain DUF1258 PF06869.7 ETO21139.1 - 0.0042 16.2 0.9 1.1 8.2 0.2 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF1258) DPPIV_N PF00930.16 ETO21139.1 - 0.0048 15.5 0.0 2.1 6.8 0.0 3.3 2 1 2 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nbas_N PF15492.1 ETO21139.1 - 0.039 13.0 0.1 0.084 11.9 0.1 1.7 1 1 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal B_lectin PF01453.19 ETO21139.1 - 0.075 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 D-mannose binding lectin Proteasome_A_N PF10584.4 ETO21139.1 - 0.099 11.9 7.0 1.3 8.4 0.1 3.4 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature AgrB PF04647.10 ETO21141.1 - 0.022 13.8 0.1 0.093 11.7 0.0 1.9 2 0 0 2 2 2 0 Accessory gene regulator B Salp15 PF12115.3 ETO21141.1 - 0.18 12.0 0.8 0.3 11.3 0.1 1.6 2 0 0 2 2 2 0 Salivary protein of 15kDa inhibits CD4+ T cell activation DUF843 PF05814.6 ETO21141.1 - 0.49 10.2 7.5 0.94 9.3 3.2 2.4 1 1 1 2 2 2 0 Baculovirus protein of unknown function (DUF843) CPSF100_C PF13299.1 ETO21142.1 - 0.0043 17.2 3.0 0.0043 17.2 2.1 2.3 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal CobT PF06213.7 ETO21142.1 - 0.18 10.8 8.5 0.049 12.7 0.8 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Zip PF02535.17 ETO21142.1 - 0.19 10.7 1.4 0.25 10.2 0.3 1.6 2 0 0 2 2 2 0 ZIP Zinc transporter FAM176 PF14851.1 ETO21142.1 - 1.6 8.4 8.3 1.8 8.2 1.2 2.5 2 0 0 2 2 2 0 FAM176 family Gag_spuma PF03276.9 ETO21142.1 - 7.7 4.7 16.9 16 3.6 11.7 1.4 1 0 0 1 1 1 0 Spumavirus gag protein IL22 PF14565.1 ETO21143.1 - 0.028 14.5 0.5 0.06 13.4 0.0 1.7 2 0 0 2 2 2 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor Utp12 PF04003.7 ETO21143.1 - 0.043 13.7 3.7 0.099 12.5 2.6 1.6 1 1 0 1 1 1 0 Dip2/Utp12 Family DUF1764 PF08576.5 ETO21144.1 - 3.9e-13 50.0 0.5 3.9e-13 50.0 0.3 3.7 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) Spore_coat_CotO PF14153.1 ETO21144.1 - 1.6e-05 24.4 3.0 1.6e-05 24.4 2.1 1.9 2 0 0 2 2 2 1 Spore coat protein CotO Miro PF08477.8 ETO21144.1 - 0.028 14.9 3.4 0.058 13.8 2.4 1.6 1 0 0 1 1 1 0 Miro-like protein Myosin_head PF00063.16 ETO21144.1 - 0.033 12.2 4.5 0.045 11.8 3.1 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) Med15 PF09606.5 ETO21144.1 - 0.073 11.2 7.5 0.087 11.0 5.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Arch_ATPase PF01637.13 ETO21144.1 - 0.4 10.3 9.4 0.76 9.4 6.5 1.4 1 0 0 1 1 1 0 Archaeal ATPase SOBP PF15279.1 ETO21144.1 - 2.8 8.2 8.5 3.7 7.8 5.9 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Pkinase PF00069.20 ETO21145.1 - 2.8e-07 29.9 0.0 3.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Herpes_UL3 PF03369.8 ETO21147.1 - 0.076 12.9 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Herpesvirus UL3 protein Daxx PF03344.10 ETO21148.1 - 0.038 12.4 22.8 0.048 12.1 15.8 1.1 1 0 0 1 1 1 0 Daxx Family RGS PF00615.14 ETO21148.1 - 0.23 11.5 0.1 0.23 11.5 0.0 2.2 2 1 0 2 2 2 0 Regulator of G protein signaling domain DUF4045 PF13254.1 ETO21148.1 - 0.64 9.2 9.2 0.95 8.6 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CENP-T PF15511.1 ETO21148.1 - 1.6 7.8 17.3 2 7.5 12.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T EspA PF03433.8 ETO21149.1 - 0.011 15.1 3.3 1.2 8.4 0.6 2.9 1 1 2 3 3 3 0 EspA-like secreted protein Methylase_S PF01420.14 ETO21149.1 - 0.07 13.1 0.2 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Type I restriction modification DNA specificity domain Rep_2 PF01719.12 ETO21149.1 - 0.41 10.1 5.1 0.18 11.2 1.6 1.7 1 1 1 2 2 2 0 Plasmid replication protein Y_phosphatase PF00102.22 ETO21150.1 - 6e-08 32.3 0.0 7.7e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 ETO21150.1 - 1.2e-07 31.3 0.0 1.4e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.7 ETO21150.1 - 0.053 12.9 0.0 0.11 11.9 0.0 1.6 1 1 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Thymopoietin PF08198.6 ETO21150.1 - 0.13 11.8 0.0 0.68 9.5 0.0 2.0 2 0 0 2 2 2 0 Thymopoietin protein CAP_GLY PF01302.20 ETO21152.1 - 3.4e-10 39.4 0.2 7.1e-10 38.4 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain S1FA PF04689.8 ETO21152.1 - 1.5 8.7 5.6 3.5 7.5 3.9 1.6 1 0 0 1 1 1 0 DNA binding protein S1FA WD40 PF00400.27 ETO21153.1 - 4.2e-31 105.6 18.5 1.7e-07 30.8 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat DUF972 PF06156.8 ETO21153.1 - 0.068 13.5 0.2 0.13 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Connexin_CCC PF10582.4 ETO21153.1 - 0.18 11.6 4.1 1.3 8.8 0.2 2.5 2 0 0 2 2 2 0 Gap junction channel protein cysteine-rich domain Snf7 PF03357.16 ETO21153.1 - 4 6.8 6.1 0.22 10.8 0.7 1.5 2 0 0 2 2 2 0 Snf7 DUF4391 PF14335.1 ETO21153.1 - 5.7 6.2 6.8 0.47 9.8 1.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4391) BSP_II PF05432.6 ETO21154.1 - 0.55 9.4 12.5 0.72 9.0 8.6 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) BUD22 PF09073.5 ETO21154.1 - 4 6.3 10.0 0.85 8.6 0.1 2.1 2 0 0 2 2 2 0 BUD22 PX PF00787.19 ETO21155.1 - 2.5e-07 30.4 0.3 1.1e-06 28.4 0.0 2.1 2 1 0 2 2 2 1 PX domain AgrB PF04647.10 ETO21155.1 - 0.04 12.9 3.6 0.069 12.2 2.5 1.3 1 0 0 1 1 1 0 Accessory gene regulator B Ras PF00071.17 ETO21157.1 - 3.2e-19 68.9 0.1 3.7e-19 68.6 0.1 1.0 1 0 0 1 1 1 1 Ras family FeoB_N PF02421.13 ETO21157.1 - 0.052 12.8 0.4 3.8 6.7 0.1 2.3 1 1 1 2 2 2 0 Ferrous iron transport protein B STAS PF01740.16 ETO21157.1 - 0.055 12.8 0.1 0.099 12.0 0.1 1.4 1 0 0 1 1 1 0 STAS domain polyprenyl_synt PF00348.12 ETO21158.1 - 1.3e-33 115.9 0.4 7.7e-18 64.2 0.1 2.9 1 1 1 2 2 2 2 Polyprenyl synthetase Orn_Arg_deC_N PF02784.11 ETO21159.1 - 6.6e-54 182.7 0.0 8.9e-54 182.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 ETO21159.1 - 5.3e-21 74.5 0.0 7.7e-21 73.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain UPF0104 PF03706.8 ETO21160.1 - 3.7e-13 49.3 25.2 2.8e-12 46.5 17.5 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0104) Ank_3 PF13606.1 ETO21162.1 - 8.4e-06 25.5 0.0 0.031 14.4 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 ETO21162.1 - 1.5e-05 25.2 0.1 0.00017 21.8 0.1 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO21162.1 - 7.1e-05 22.4 0.1 0.048 13.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 ETO21162.1 - 9e-05 22.5 0.0 0.041 14.1 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO21162.1 - 0.00094 19.6 0.0 2.3 8.8 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) KaiB PF07689.7 ETO21163.1 - 0.057 12.8 1.2 0.13 11.7 0.0 2.3 2 0 0 2 2 2 0 KaiB domain RasGEF PF00617.14 ETO21164.1 - 2.4e-09 37.1 5.9 0.00047 19.9 0.0 3.4 3 1 0 3 3 3 2 RasGEF domain RasGEF_N PF00618.15 ETO21164.1 - 0.024 14.7 0.1 0.024 14.7 0.1 2.9 2 1 0 2 2 2 0 RasGEF N-terminal motif Apis_Csd PF11671.3 ETO21164.1 - 0.042 13.6 4.8 0.36 10.6 0.9 2.6 3 0 0 3 3 3 0 Complementary sex determiner protein Kelch_1 PF01344.20 ETO21165.1 - 0.024 14.1 3.7 0.36 10.4 0.7 3.7 4 0 0 4 4 4 0 Kelch motif Kelch_6 PF13964.1 ETO21165.1 - 0.026 14.7 6.9 0.58 10.4 0.1 4.4 4 0 0 4 4 4 0 Kelch motif AD PF09793.4 ETO21166.1 - 0.0003 20.5 0.1 0.0003 20.5 0.1 2.3 3 0 0 3 3 3 1 Anticodon-binding domain PaaB PF06243.6 ETO21167.1 - 0.048 13.7 0.1 0.071 13.2 0.0 1.6 1 1 0 1 1 1 0 Phenylacetic acid degradation B TcpF PF06340.6 ETO21167.1 - 0.063 12.3 0.0 0.068 12.2 0.0 1.2 1 0 0 1 1 1 0 Vibrio cholerae toxin co-regulated pilus biosynthesis protein F Rad50_zn_hook PF04423.9 ETO21168.1 - 0.28 10.6 3.0 0.44 10.0 1.0 2.1 2 0 0 2 2 2 0 Rad50 zinc hook motif Laminin_G_3 PF13385.1 ETO21169.1 - 9.5e-07 29.1 0.3 1.5e-06 28.4 0.2 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Ribosomal_S27e PF01667.12 ETO21169.1 - 0.022 14.2 0.0 0.052 13.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S27 RXT2_N PF08595.6 ETO21170.1 - 0.19 11.5 27.2 0.12 12.2 5.3 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal NOA36 PF06524.7 ETO21170.1 - 3.4 6.8 27.1 0.14 11.3 5.4 2.2 2 0 0 2 2 2 0 NOA36 protein Utp14 PF04615.8 ETO21170.1 - 5.2 5.0 46.2 6.1 4.8 32.0 1.1 1 0 0 1 1 1 0 Utp14 protein DUF4366 PF14283.1 ETO21170.1 - 7.5 5.9 24.7 0.45 9.9 5.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) ABC_tran PF00005.22 ETO21171.1 - 3.4e-08 33.8 0.0 3.4e-08 33.8 0.0 2.2 2 1 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 ETO21171.1 - 3.1e-05 23.5 0.3 4.9e-05 22.8 0.2 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SbcCD_C PF13558.1 ETO21171.1 - 0.0044 16.9 0.4 0.26 11.2 0.0 3.2 3 0 0 3 3 3 1 Putative exonuclease SbcCD, C subunit Lipoprotein_2 PF00921.12 ETO21171.1 - 0.037 14.0 8.5 0.058 13.4 5.9 1.2 1 0 0 1 1 1 0 Borrelia lipoprotein DUF3439 PF11921.3 ETO21171.1 - 0.31 10.8 14.2 0.72 9.6 9.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Band_3_cyto PF07565.8 ETO21171.1 - 3.5 7.0 7.3 5.4 6.4 5.1 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain cNMP_binding PF00027.24 ETO21172.1 - 5.4e-26 90.2 0.1 2.8e-16 59.1 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DUF1161 PF06649.7 ETO21172.1 - 0.049 13.5 0.2 0.33 10.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1161) U1snRNP70_N PF12220.3 ETO21172.1 - 3.8 7.9 6.1 28 5.1 0.1 2.3 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal MHC2-interact PF09307.5 ETO21173.1 - 0.53 10.0 8.2 1.1 9.0 5.7 1.5 1 0 0 1 1 1 0 CLIP, MHC2 interacting Ldh_1_N PF00056.18 ETO21175.1 - 5.5e-34 117.0 0.0 7e-34 116.6 0.0 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 ETO21175.1 - 0.16 11.6 0.1 0.28 10.8 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain zf-C3HC4_2 PF13923.1 ETO21177.1 - 0.004 17.1 3.4 0.034 14.1 2.3 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO21177.1 - 0.014 15.2 6.6 0.059 13.2 4.6 2.2 1 1 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.2 ETO21177.1 - 0.027 14.5 2.6 0.027 14.5 1.8 2.3 2 2 0 2 2 2 0 RING-H2 zinc finger Cortex-I_coil PF09304.5 ETO21177.1 - 0.17 11.9 7.6 0.068 13.2 3.2 1.8 2 0 0 2 2 2 0 Cortexillin I, coiled coil NBP1 PF08537.5 ETO21177.1 - 1.1 8.4 10.3 4.1 6.5 4.4 2.1 1 1 1 2 2 2 0 Fungal Nap binding protein NBP1 B56 PF01603.15 ETO21178.1 - 2.4e-98 329.4 7.2 2.8e-98 329.2 5.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) G-alpha PF00503.15 ETO21179.1 - 9.8e-64 215.4 19.1 4.5e-34 117.7 2.5 2.1 2 0 0 2 2 2 2 G-protein alpha subunit DUF815 PF05673.8 ETO21179.1 - 0.0064 15.4 0.2 0.0098 14.8 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 ETO21179.1 - 0.011 15.2 0.2 0.024 14.1 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 ETO21179.1 - 0.023 14.2 0.2 0.046 13.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 ETO21179.1 - 0.05 13.8 3.1 0.13 12.5 2.0 1.8 1 1 0 1 1 1 0 ABC transporter AAA_17 PF13207.1 ETO21179.1 - 0.09 13.6 0.2 0.3 11.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain Herpes_gE PF02480.11 ETO21181.1 - 0.00012 20.4 0.5 0.0039 15.5 0.0 2.0 1 1 1 2 2 2 2 Alphaherpesvirus glycoprotein E Metal_resist PF13801.1 ETO21181.1 - 0.21 11.5 1.5 0.62 10.0 0.1 2.0 1 1 1 2 2 2 0 Heavy-metal resistance Trypan_PARP PF05887.6 ETO21181.1 - 1.2 8.9 9.9 8.9 6.1 6.4 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF4206 PF13901.1 ETO21182.1 - 8.8e-12 45.0 5.0 1.3e-10 41.2 0.8 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF4206) WD40 PF00400.27 ETO21183.1 - 9.8e-62 202.7 23.4 1.8e-12 46.5 0.1 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO21183.1 - 1.3e-10 40.0 1.4 0.00057 18.1 0.0 4.8 2 1 3 5 5 5 4 Nucleoporin Nup120/160 DUF3794 PF12673.2 ETO21183.1 - 0.087 12.9 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3794) TetM_leader PF08076.6 ETO21183.1 - 0.25 10.9 12.5 0.37 10.3 0.0 3.7 4 0 0 4 4 4 0 Tetracycline resistance determinant leader peptide ATG16 PF08614.6 ETO21183.1 - 4 7.1 8.1 7.2 6.3 5.6 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) zf-TRAF PF02176.13 ETO21184.1 - 2.3e-06 27.8 1.5 2.3e-06 27.8 1.0 3.0 2 1 0 2 2 2 1 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 ETO21184.1 - 2.5 8.1 8.4 0.69 9.9 0.5 3.5 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) NRDE-2 PF08424.5 ETO21185.1 - 0.043 12.6 0.4 0.066 12.0 0.3 1.2 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference zf-C2H2 PF00096.21 ETO21186.1 - 2.7e-17 61.9 33.0 2.5e-05 24.3 0.3 6.3 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETO21186.1 - 2.2e-16 58.8 35.0 0.00029 20.9 0.8 6.3 6 0 0 6 6 6 5 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETO21186.1 - 6.7e-10 38.7 29.5 0.001 19.2 0.3 6.5 6 0 0 6 6 6 4 Zinc-finger double domain zf-Di19 PF05605.7 ETO21186.1 - 1.7e-05 24.8 3.7 1.7e-05 24.8 2.6 4.2 1 1 2 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 ETO21186.1 - 0.00027 20.9 0.7 0.00027 20.9 0.5 6.0 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 ETO21186.1 - 0.0028 17.8 0.3 0.0028 17.8 0.2 6.0 6 1 1 7 7 7 2 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 ETO21186.1 - 0.049 13.5 11.1 0.55 10.2 0.1 4.4 4 0 0 4 4 4 0 Zinc ribbon domain zf-RING_3 PF14369.1 ETO21186.1 - 0.18 11.8 8.1 3.3 7.7 0.1 3.9 4 0 0 4 4 4 0 zinc-finger zf-C2H2_2 PF12756.2 ETO21186.1 - 0.47 10.5 24.5 1.8 8.7 0.9 3.7 1 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) GAGA PF09237.6 ETO21186.1 - 0.51 9.9 19.3 4.2 7.0 0.1 5.1 3 2 2 5 5 5 0 GAGA factor COX5B PF01215.14 ETO21186.1 - 1.1 8.9 5.9 0.81 9.3 0.9 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Vb zf-BED PF02892.10 ETO21186.1 - 1.3 8.8 26.3 0.6 9.9 2.8 4.6 4 2 1 5 5 5 0 BED zinc finger A2L_zn_ribbon PF08792.5 ETO21186.1 - 5.4 6.6 17.4 4.6 6.8 0.3 4.4 4 0 0 4 4 4 0 A2L zinc ribbon domain VPS9 PF02204.13 ETO21187.1 - 2.4e-14 53.2 1.7 4e-14 52.4 0.0 2.2 3 0 0 3 3 3 1 Vacuolar sorting protein 9 (VPS9) domain RAP1 PF07218.6 ETO21188.1 - 0.0082 14.3 3.3 0.011 13.8 2.3 1.1 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) Elf1 PF05129.8 ETO21188.1 - 1.3 8.7 8.2 6.8 6.4 1.7 2.5 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like MBT PF02820.13 ETO21189.1 - 4.4e-05 23.3 0.1 0.00015 21.6 0.0 1.9 2 0 0 2 2 2 1 mbt repeat Coiled-coil_56 PF09813.4 ETO21189.1 - 0.014 15.3 0.1 4 7.4 0.1 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 Tudor-knot PF11717.3 ETO21189.1 - 0.041 13.6 0.2 0.16 11.7 0.1 2.1 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Hydrolase_3 PF08282.7 ETO21191.1 - 1.9 8.0 5.5 3.8 7.0 1.7 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Snf7 PF03357.16 ETO21192.1 - 1.1e-05 24.8 10.9 1.5e-05 24.4 7.6 1.0 1 0 0 1 1 1 1 Snf7 CCDC155 PF14662.1 ETO21192.1 - 0.0035 16.9 4.3 0.0036 16.9 3.0 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 ATP-synt_D PF01813.12 ETO21192.1 - 0.0066 16.0 5.0 0.0076 15.8 3.5 1.0 1 0 0 1 1 1 1 ATP synthase subunit D DUF972 PF06156.8 ETO21192.1 - 0.013 15.8 3.2 0.016 15.5 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF29 PF01724.11 ETO21192.1 - 0.014 15.2 1.8 0.016 15.0 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF29 Nnf1 PF03980.9 ETO21192.1 - 0.028 14.4 2.9 0.047 13.6 2.0 1.4 1 0 0 1 1 1 0 Nnf1 COQ7 PF03232.8 ETO21192.1 - 0.081 12.3 1.1 0.093 12.1 0.8 1.1 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 DUF3086 PF11285.3 ETO21192.1 - 0.092 11.5 2.4 0.094 11.5 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) MRP-S27 PF10037.4 ETO21192.1 - 0.098 11.5 3.5 0.11 11.3 2.5 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Hist_deacetyl PF00850.14 ETO21192.1 - 0.1 11.8 0.2 0.12 11.6 0.1 1.0 1 0 0 1 1 1 0 Histone deacetylase domain IncA PF04156.9 ETO21192.1 - 0.11 12.0 3.1 0.12 11.9 2.2 1.1 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 ETO21192.1 - 0.12 11.9 8.8 0.14 11.6 4.1 2.1 2 0 0 2 2 2 0 Septum formation initiator DUF2229 PF09989.4 ETO21192.1 - 0.16 11.3 1.5 0.18 11.2 1.0 1.1 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF4140 PF13600.1 ETO21192.1 - 0.22 11.9 5.1 0.33 11.4 3.5 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) TMPIT PF07851.8 ETO21192.1 - 0.27 10.2 4.1 0.29 10.1 2.8 1.0 1 0 0 1 1 1 0 TMPIT-like protein Sec20 PF03908.8 ETO21192.1 - 0.34 10.6 4.3 2 8.1 0.1 2.1 1 1 1 2 2 2 0 Sec20 TSC22 PF01166.13 ETO21192.1 - 0.46 10.4 2.8 0.97 9.4 1.9 1.7 1 1 0 1 1 1 0 TSC-22/dip/bun family DUF3573 PF12097.3 ETO21192.1 - 0.63 8.5 3.2 0.76 8.3 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) OmpH PF03938.9 ETO21192.1 - 0.7 9.8 11.8 0.82 9.5 8.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF342 PF03961.8 ETO21192.1 - 0.72 8.2 7.0 0.8 8.0 4.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Atg14 PF10186.4 ETO21192.1 - 0.74 8.7 7.6 0.8 8.5 5.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Casc1 PF12366.3 ETO21192.1 - 0.93 8.9 5.8 1 8.7 4.0 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 Peptidase_S49_N PF08496.5 ETO21192.1 - 0.99 9.1 5.0 1.1 9.0 3.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal HK97-gp10_like PF04883.7 ETO21192.1 - 1.7 9.6 4.6 2.6 9.0 3.2 1.3 1 0 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component DUF106 PF01956.11 ETO21192.1 - 2 7.9 6.0 2.2 7.7 4.1 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 Bac_export_2 PF01312.14 ETO21192.1 - 2.1 7.1 6.4 1.4 7.6 0.4 2.2 1 1 1 2 2 2 0 FlhB HrpN YscU SpaS Family DUF3987 PF13148.1 ETO21192.1 - 3.2 6.2 7.5 3.5 6.0 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Vps51 PF08700.6 ETO21192.1 - 3.3 7.5 6.5 2 8.2 2.6 2.0 2 1 1 3 3 3 0 Vps51/Vps67 LMBR1 PF04791.11 ETO21192.1 - 4 5.9 4.9 4.7 5.6 3.4 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1843 PF08898.5 ETO21192.1 - 6.5 6.8 8.0 4.4 7.4 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1843) zinc_ribbon_2 PF13240.1 ETO21193.1 - 0.49 9.9 3.9 11 5.7 1.1 3.0 2 0 0 2 2 2 0 zinc-ribbon domain zf-CCHC_4 PF14392.1 ETO21193.1 - 0.71 9.5 8.1 0.082 12.5 0.7 2.8 3 0 0 3 3 3 0 Zinc knuckle WD40 PF00400.27 ETO21194.1 - 1.7e-08 34.0 0.1 2.9e-07 30.1 0.0 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat PAP_RNA-bind PF04926.10 ETO21196.1 - 0.0014 18.1 0.2 0.0028 17.2 0.2 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain P_gingi_FimA PF06321.6 ETO21196.1 - 0.087 12.0 1.2 3 6.9 0.0 2.8 2 1 1 3 3 3 0 Major fimbrial subunit protein (FimA) Acyl-ACP_TE PF01643.12 ETO21197.1 - 0.0028 16.6 0.1 0.0051 15.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-ACP thioesterase DUF4427 PF14468.1 ETO21197.1 - 0.05 13.3 0.1 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4427) Med19 PF10278.4 ETO21198.1 - 0.0058 16.3 5.0 0.0058 16.3 3.4 2.0 2 0 0 2 2 2 1 Mediator of RNA pol II transcription subunit 19 CDC45 PF02724.9 ETO21198.1 - 0.16 9.9 12.9 0.22 9.5 9.0 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 ETO21198.1 - 0.94 8.6 13.1 1.4 8.0 9.1 1.3 1 0 0 1 1 1 0 NOA36 protein SRP-alpha_N PF04086.8 ETO21198.1 - 1.9 7.8 22.1 2.4 7.4 15.3 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Dicty_REP PF05086.7 ETO21198.1 - 8.7 3.9 24.8 0.93 7.1 14.4 1.4 1 1 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF1183 PF06682.7 ETO21199.1 - 0.0071 15.9 11.9 0.0094 15.5 8.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) Corona_nucleoca PF00937.13 ETO21199.1 - 0.4 9.5 3.4 0.56 9.0 2.4 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Alpha_kinase PF02816.13 ETO21200.1 - 6.9e-42 143.2 0.4 1.4e-41 142.2 0.3 1.5 1 0 0 1 1 1 1 Alpha-kinase family Sugarporin_N PF11471.3 ETO21201.1 - 0.23 11.1 4.4 0.19 11.4 0.7 2.6 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension DUF2065 PF09838.4 ETO21202.1 - 0.081 12.6 0.1 1.2 8.8 0.1 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2065) DUF2232 PF09991.4 ETO21202.1 - 0.1 11.5 0.5 3.1 6.6 0.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) Gal4_dimer PF03902.8 ETO21202.1 - 0.11 12.4 0.6 0.24 11.3 0.4 1.5 1 0 0 1 1 1 0 Gal4-like dimerisation domain OTCace_N PF02729.16 ETO21203.1 - 1.7e-37 128.2 0.0 2.4e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Kelch_3 PF13415.1 ETO21204.1 - 5.9e-07 29.4 0.2 0.018 15.2 0.0 3.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO21204.1 - 8.9e-06 25.1 7.1 0.0032 16.9 0.5 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO21204.1 - 2e-05 24.5 6.8 0.0087 16.2 0.1 4.3 4 1 1 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO21204.1 - 4.4e-05 23.1 5.0 0.15 11.8 0.0 5.5 7 0 0 7 7 7 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO21204.1 - 0.00014 21.5 4.4 0.0067 16.1 0.1 4.0 4 0 0 4 4 4 1 Kelch motif FH2 PF02181.18 ETO21205.1 - 1.6e-15 56.9 2.4 1.6e-15 56.9 1.7 2.0 1 1 1 2 2 2 1 Formin Homology 2 Domain Linker_histone PF00538.14 ETO21205.1 - 0.2 11.7 3.7 0.56 10.3 0.0 2.5 2 0 0 2 2 2 0 linker histone H1 and H5 family ORC5_C PF14630.1 ETO21205.1 - 5.1 6.4 7.9 1.2 8.4 2.8 1.8 2 1 0 2 2 2 0 Origin recognition complex (ORC) subunit 5 C-terminus Tropomodulin PF03250.9 ETO21205.1 - 5.7 6.4 10.4 9.7 5.7 3.9 2.5 1 1 1 2 2 2 0 Tropomodulin FH2 PF02181.18 ETO21206.1 - 6.5e-60 202.9 0.5 3.3e-59 200.6 0.3 2.1 1 1 0 1 1 1 1 Formin Homology 2 Domain DUF2360 PF10152.4 ETO21206.1 - 1.7e-08 34.8 4.4 1.5e-05 25.3 0.2 5.3 5 1 0 5 5 5 2 Predicted coiled-coil domain-containing protein (DUF2360) Drf_GBD PF06371.8 ETO21206.1 - 3e-07 29.9 0.3 1.1e-06 28.1 0.0 2.2 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain RskA PF10099.4 ETO21206.1 - 0.54 9.9 10.7 1.1 8.9 7.4 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF4512 PF14975.1 ETO21206.1 - 0.85 10.4 0.0 0.85 10.4 0.0 4.7 4 1 0 4 4 4 0 Domain of unknown function (DUF4512) CAP_GLY PF01302.20 ETO21207.1 - 8.5e-13 47.8 0.7 2.1e-12 46.5 0.5 1.6 1 0 0 1 1 1 1 CAP-Gly domain Corona_nucleoca PF00937.13 ETO21209.1 - 3.2e-05 23.0 14.9 3.2e-05 23.0 10.4 2.1 2 0 0 2 2 2 1 Coronavirus nucleocapsid protein Daxx PF03344.10 ETO21209.1 - 0.00011 20.8 28.1 0.00011 20.8 19.5 1.6 2 0 0 2 2 2 1 Daxx Family DUF1777 PF08648.7 ETO21209.1 - 0.0051 16.5 30.2 0.0051 16.5 20.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) Nucleo_P87 PF07267.6 ETO21209.1 - 0.0057 15.4 12.4 0.012 14.3 8.6 1.5 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 Abhydrolase_1 PF00561.15 ETO21209.1 - 0.053 13.0 0.1 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Transformer PF06495.6 ETO21209.1 - 3.9 7.2 29.1 0.097 12.5 14.6 2.4 3 0 0 3 3 3 0 Fruit fly transformer protein DUF1509 PF07420.6 ETO21209.1 - 4.4 6.4 32.2 0.67 9.1 19.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1509) Nop14 PF04147.7 ETO21209.1 - 6.7 4.4 28.3 11 3.7 19.6 1.3 1 0 0 1 1 1 0 Nop14-like family PDZ_2 PF13180.1 ETO21210.1 - 2.3e-10 40.1 0.0 1.1e-09 38.0 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.19 ETO21210.1 - 0.007 16.5 0.0 0.019 15.1 0.0 1.7 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) RasGEF PF00617.14 ETO21211.1 - 3.8e-05 23.4 0.1 0.00016 21.4 0.1 2.0 1 1 0 1 1 1 1 RasGEF domain GBV-C_env PF12786.2 ETO21211.1 - 0.067 11.6 0.0 0.089 11.2 0.0 1.2 1 0 0 1 1 1 0 GB virus C genotype envelope Ribul_P_3_epim PF00834.14 ETO21212.1 - 6.1e-64 214.8 0.6 5.1e-63 211.8 0.4 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family Drf_GBD PF06371.8 ETO21212.1 - 0.041 13.2 0.1 0.08 12.2 0.0 1.4 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain QRPTase_C PF01729.14 ETO21212.1 - 0.072 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain WD40 PF00400.27 ETO21213.1 - 4.6e-52 172.1 9.6 1.9e-12 46.5 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat PD40 PF07676.7 ETO21213.1 - 0.0016 18.0 0.4 30 4.4 0.0 4.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO21213.1 - 0.0022 16.3 0.1 0.14 10.4 0.0 2.4 2 0 0 2 2 2 1 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO21213.1 - 0.0035 16.4 1.3 0.48 9.4 0.0 3.3 2 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal DdrB PF12747.2 ETO21213.1 - 0.0051 16.5 0.3 0.19 11.4 0.1 2.5 2 1 0 2 2 2 1 DdrB-like protein SGL PF08450.7 ETO21213.1 - 0.012 15.0 0.2 0.54 9.5 0.0 2.5 1 1 1 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 ETO21213.1 - 0.014 15.4 0.0 13 5.9 0.0 3.9 1 1 3 4 4 4 0 Strictosidine synthase PLD_C PF12357.3 ETO21213.1 - 0.036 13.5 0.1 51 3.5 0.0 3.6 4 0 0 4 4 4 0 Phospholipase D C terminal PQQ PF01011.16 ETO21213.1 - 0.077 12.5 0.0 8.7 6.0 0.0 3.7 3 0 0 3 3 3 0 PQQ enzyme repeat Proteasome_A_N PF10584.4 ETO21213.1 - 0.35 10.2 4.8 31 4.0 0.0 4.5 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature ParB PF08775.5 ETO21214.1 - 0.43 10.9 11.1 3.4 8.0 2.7 3.0 1 1 1 3 3 3 0 ParB family HlyD PF00529.15 ETO21214.1 - 0.46 9.7 8.5 0.016 14.5 1.9 1.5 2 0 0 2 2 2 0 HlyD family secretion protein Syntaxin-6_N PF09177.6 ETO21214.1 - 1.1 9.6 14.2 12 6.4 2.4 3.5 3 0 0 3 3 3 0 Syntaxin 6, N-terminal TPR_MLP1_2 PF07926.7 ETO21214.1 - 1.6 8.5 26.4 0.047 13.4 8.3 3.1 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4164 PF13747.1 ETO21214.1 - 1.8 8.7 11.7 1.9 8.6 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) NYD-SP28 PF14772.1 ETO21214.1 - 5.9 7.0 17.5 4.1 7.5 2.7 2.6 2 0 0 2 2 2 0 Sperm tail Clat_adaptor_s PF01217.15 ETO21215.1 - 1.3e-06 28.1 0.1 2e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Phage_GP20 PF06810.6 ETO21215.1 - 0.95 8.8 8.0 1.1 8.7 2.4 2.5 2 1 0 2 2 2 0 Phage minor structural protein GP20 Mito_fiss_reg PF05308.6 ETO21216.1 - 0.017 14.4 1.4 0.027 13.8 1.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator HEAT PF02985.17 ETO21217.1 - 0.011 15.7 0.1 1.4 9.1 0.0 2.9 2 0 0 2 2 2 0 HEAT repeat DUF2431 PF10354.4 ETO21218.1 - 4.1e-10 39.8 0.1 4.8e-10 39.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Actin PF00022.14 ETO21219.1 - 4.5e-74 249.2 0.0 5e-74 249.0 0.0 1.0 1 0 0 1 1 1 1 Actin Amdo_NSP PF12475.3 ETO21220.1 - 0.0089 15.9 1.9 0.025 14.4 0.1 2.4 2 1 0 2 2 2 1 Amdovirus non-structural protein Lsm_C PF14894.1 ETO21220.1 - 0.17 11.4 0.3 4.4 6.8 0.0 2.2 2 0 0 2 2 2 0 Lsm C-terminal zf-TRAF PF02176.13 ETO21221.1 - 9.9e-05 22.6 9.9 9.9e-05 22.6 6.9 4.0 3 1 1 4 4 4 1 TRAF-type zinc finger TMCO5 PF14992.1 ETO21221.1 - 0.0041 16.3 0.9 0.0041 16.3 0.6 2.1 2 0 0 2 2 2 1 TMCO5 family zf-CCHC PF00098.18 ETO21221.1 - 0.035 14.0 0.3 0.035 14.0 0.2 3.8 4 0 0 4 4 4 0 Zinc knuckle zf-C2H2 PF00096.21 ETO21221.1 - 4.5 7.8 10.5 1.4 9.3 0.3 4.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type Afi1 PF07792.7 ETO21222.1 - 0.1 12.5 3.5 0.19 11.7 2.4 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SUZ PF12752.2 ETO21223.1 - 5.3 7.6 7.4 2.3 8.7 3.3 1.8 1 1 1 2 2 2 0 SUZ domain Nop14 PF04147.7 ETO21225.1 - 0.0066 14.4 8.1 0.0067 14.4 5.6 1.1 1 0 0 1 1 1 1 Nop14-like family FAM222A PF15258.1 ETO21225.1 - 0.0098 15.1 2.4 0.012 14.9 1.7 1.0 1 0 0 1 1 1 1 Protein family of FAM222A Sporozoite_P67 PF05642.6 ETO21225.1 - 0.013 13.4 4.9 0.015 13.2 3.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen OHCU_decarbox PF09349.5 ETO21225.1 - 0.015 15.6 2.4 0.017 15.4 1.6 1.2 1 0 0 1 1 1 0 OHCU decarboxylase BTV_NS2 PF04514.7 ETO21225.1 - 0.034 13.0 7.3 0.038 12.8 5.0 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Peptidase_S49_N PF08496.5 ETO21225.1 - 0.069 12.9 4.6 0.098 12.4 3.2 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal HCV_NS5a_C PF12941.2 ETO21225.1 - 0.079 12.5 1.8 0.1 12.1 1.3 1.2 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region RAI16-like PF10257.4 ETO21225.1 - 0.095 11.6 1.1 0.19 10.6 0.8 1.6 1 1 0 1 1 1 0 Retinoic acid induced 16-like protein Cytomega_UL84 PF06284.6 ETO21225.1 - 0.096 11.0 2.8 0.11 10.9 1.9 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein FLO_LFY PF01698.11 ETO21225.1 - 0.15 10.8 4.0 0.18 10.6 2.8 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Ycf1 PF05758.7 ETO21225.1 - 0.19 9.4 6.0 0.19 9.3 4.2 1.2 1 0 0 1 1 1 0 Ycf1 Nucleo_P87 PF07267.6 ETO21225.1 - 0.21 10.2 6.2 0.26 9.9 4.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FAM176 PF14851.1 ETO21225.1 - 0.21 11.2 6.2 0.36 10.4 4.3 1.4 1 0 0 1 1 1 0 FAM176 family FUSC-like PF12805.2 ETO21225.1 - 0.33 9.8 4.9 0.24 10.2 2.3 1.5 1 1 0 1 1 1 0 FUSC-like inner membrane protein yccS CENP-B_dimeris PF09026.5 ETO21225.1 - 0.38 11.0 12.9 0.88 9.8 9.0 1.7 1 1 0 1 1 1 0 Centromere protein B dimerisation domain PBP_sp32 PF07222.7 ETO21225.1 - 0.91 8.6 9.4 1.3 8.1 6.5 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 GAGA_bind PF06217.7 ETO21225.1 - 1 9.2 5.7 1.2 9.0 4.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family CDC45 PF02724.9 ETO21225.1 - 1.8 6.5 10.0 2 6.3 7.0 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_3_Rpc31 PF11705.3 ETO21225.1 - 1.8 8.4 17.3 2.8 7.8 12.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PBP1_TM PF14812.1 ETO21225.1 - 2 8.7 10.4 3.8 7.8 7.2 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TMEM51 PF15345.1 ETO21225.1 - 2.9 7.5 7.3 1.3 8.6 3.5 1.5 2 0 0 2 2 2 0 Transmembrane protein 51 S-antigen PF05756.6 ETO21225.1 - 5.2 7.1 8.9 8.2 6.4 6.2 1.4 1 0 0 1 1 1 0 S-antigen protein DUF4611 PF15387.1 ETO21225.1 - 6.4 6.9 13.3 5.5 7.2 8.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) GAPT PF11770.3 ETO21226.1 - 0.021 14.4 0.2 0.051 13.2 0.1 1.6 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) PH_6 PF15406.1 ETO21226.1 - 0.029 14.4 1.2 0.093 12.7 0.1 2.3 2 1 0 2 2 2 0 Pleckstrin homology domain Mcp5_PH PF12814.2 ETO21226.1 - 0.1 12.5 2.6 2.1 8.2 0.0 3.0 3 1 0 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology DUF1136 PF06582.7 ETO21226.1 - 0.48 10.1 2.2 10 5.9 0.1 2.6 2 1 0 2 2 2 0 Repeat of unknown function (DUF1136) PH PF00169.24 ETO21226.1 - 0.63 10.2 5.0 0.28 11.3 0.9 2.1 2 1 0 2 2 2 0 PH domain DUF303 PF03629.13 ETO21227.1 - 3.5e-32 111.6 0.0 2.6e-31 108.7 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF303) PX PF00787.19 ETO21229.1 - 7.6e-12 45.0 0.1 1.2e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 PX domain PLU-1 PF08429.6 ETO21230.1 - 9.4e-16 57.6 13.7 1.8e-09 36.9 3.1 4.6 2 2 1 3 3 3 3 PLU-1-like protein PHD PF00628.24 ETO21230.1 - 7.2e-05 22.4 3.4 0.00028 20.5 2.3 2.0 1 0 0 1 1 1 1 PHD-finger Peptidase_S49_N PF08496.5 ETO21230.1 - 3.1 7.5 14.6 0.035 13.9 1.4 3.5 3 0 0 3 3 3 0 Peptidase family S49 N-terminal FYVE PF01363.16 ETO21231.1 - 1.6e-07 31.0 7.8 1.6e-07 31.0 5.4 1.9 1 1 0 1 1 1 1 FYVE zinc finger DUF3165 PF11364.3 ETO21232.1 - 0.03 14.4 0.2 6 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3165) DnaI_N PF07319.6 ETO21232.1 - 3.1 8.0 6.2 0.85 9.9 0.3 2.8 2 2 1 3 3 3 0 Primosomal protein DnaI N-terminus Beta_helix PF13229.1 ETO21235.1 - 1.4e-05 24.9 15.3 1.6e-05 24.6 9.8 1.7 1 1 0 1 1 1 1 Right handed beta helix region Chlam_PMP PF02415.12 ETO21235.1 - 0.013 15.6 22.5 0.038 14.2 0.2 5.7 6 0 0 6 6 6 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Beta_helix PF13229.1 ETO21236.1 - 0.0012 18.6 0.7 0.002 17.9 0.5 1.3 1 0 0 1 1 1 1 Right handed beta helix region RDD PF06271.7 ETO21236.1 - 0.01 15.7 2.2 0.01 15.7 1.6 1.7 2 0 0 2 2 2 0 RDD family Chlam_PMP PF02415.12 ETO21236.1 - 0.018 15.2 11.3 0.023 14.9 0.2 4.2 5 0 0 5 5 5 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat NosD PF05048.8 ETO21236.1 - 0.034 13.3 0.6 0.045 12.9 0.4 1.1 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) zf-LITAF-like PF10601.4 ETO21236.1 - 0.097 12.5 0.1 0.097 12.5 0.0 2.6 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain DUF912 PF06024.7 ETO21236.1 - 0.48 10.5 1.9 3.2 7.8 0.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PAT1 PF09770.4 ETO21238.1 - 0.14 10.3 43.6 0.18 10.0 30.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Guanylate_cyc PF00211.15 ETO21240.1 - 1.1e-17 64.0 0.0 1.6e-09 37.3 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.1 ETO21240.1 - 3.2e-10 40.3 0.9 5.3e-10 39.5 0.1 1.7 2 0 0 2 2 2 1 AAA ATPase domain PH PF00169.24 ETO21240.1 - 3e-07 30.5 0.6 1.1e-06 28.7 0.4 2.1 1 0 0 1 1 1 1 PH domain AAA_22 PF13401.1 ETO21240.1 - 5.8e-05 23.2 0.1 0.0017 18.4 0.1 2.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 ETO21240.1 - 0.00016 21.6 0.1 4.4 7.2 0.0 3.7 3 0 0 3 3 3 2 AAA domain Arch_ATPase PF01637.13 ETO21240.1 - 0.00034 20.4 0.1 0.0015 18.2 0.1 2.1 1 1 0 1 1 1 1 Archaeal ATPase NB-ARC PF00931.17 ETO21240.1 - 0.0086 14.9 1.8 0.01 14.6 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain PH_11 PF15413.1 ETO21240.1 - 0.019 15.2 4.2 0.031 14.5 0.0 3.4 3 0 0 3 3 3 0 Pleckstrin homology domain GvpL_GvpF PF06386.6 ETO21241.1 - 0.87 9.1 6.3 0.27 10.7 2.2 1.6 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF RhoGEF PF00621.15 ETO21242.1 - 3.1e-17 63.0 5.6 7.7e-17 61.7 1.9 2.1 2 0 0 2 2 2 1 RhoGEF domain FYVE PF01363.16 ETO21242.1 - 1.8e-06 27.7 1.7 4.2e-06 26.5 1.2 1.6 1 0 0 1 1 1 1 FYVE zinc finger POX PF07526.6 ETO21242.1 - 0.99 9.6 5.3 1.6 8.9 0.8 2.3 2 0 0 2 2 2 0 Associated with HOX Reo_sigmaC PF04582.7 ETO21243.1 - 0.21 10.7 17.3 0.53 9.4 0.8 3.5 2 1 2 4 4 4 0 Reovirus sigma C capsid protein ART PF01129.13 ETO21244.1 - 0.01 14.9 0.1 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase PUB PF09409.5 ETO21244.1 - 0.024 14.3 0.7 0.024 14.3 0.5 2.9 2 1 0 2 2 2 0 PUB domain CW_binding_1 PF01473.15 ETO21244.1 - 0.038 14.0 1.2 0.16 12.1 0.8 2.2 1 0 0 1 1 1 0 Putative cell wall binding repeat Eapp_C PF10238.4 ETO21245.1 - 0.056 13.3 29.7 0.019 14.8 2.5 3.5 3 0 0 3 3 3 0 E2F-associated phosphoprotein DUF3300 PF11737.3 ETO21245.1 - 7.6 5.7 11.8 8.6 5.5 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3300) RPAP2_Rtr1 PF04181.8 ETO21246.1 - 8.2e-12 45.0 0.2 8.2e-12 45.0 0.2 2.7 2 1 0 2 2 2 1 Rtr1/RPAP2 family CDC45 PF02724.9 ETO21246.1 - 0.23 9.4 12.1 0.4 8.6 8.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Mem_trans PF03547.13 ETO21246.1 - 5.6 5.1 9.5 0.9 7.7 0.7 2.1 2 0 0 2 2 2 0 Membrane transport protein RRM_1 PF00076.17 ETO21247.1 - 1.2e-17 63.2 0.0 1.8e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO21247.1 - 4.1e-11 42.6 0.0 6.9e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO21247.1 - 1.1e-06 28.3 0.0 1.8e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETO21247.1 - 0.00051 19.7 0.2 0.0011 18.6 0.0 1.7 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.6 ETO21247.1 - 2.4 7.7 4.8 9 5.8 1.7 2.8 1 1 1 2 2 2 0 Ribonuclease B OB domain Menin PF05053.8 ETO21249.1 - 0.044 11.9 6.3 0.064 11.4 4.3 1.3 1 0 0 1 1 1 0 Menin EF-hand_8 PF13833.1 ETO21250.1 - 0.39 10.3 3.3 7.7 6.2 0.5 2.5 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_7 PF13499.1 ETO21250.1 - 0.4 10.8 4.6 0.38 10.9 1.0 2.4 2 1 1 3 3 3 0 EF-hand domain pair CytochromB561_N PF09786.4 ETO21250.1 - 2.3 6.5 14.3 3 6.2 9.9 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Macoilin PF09726.4 ETO21250.1 - 2.6 6.2 17.5 2.8 6.1 12.1 1.1 1 0 0 1 1 1 0 Transmembrane protein RVT_1 PF00078.22 ETO21251.1 - 0.027 13.8 3.2 0.042 13.1 0.8 2.2 1 1 1 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) USP7_C2 PF14533.1 ETO21251.1 - 0.037 13.4 2.7 0.047 13.1 0.2 1.9 1 1 1 2 2 2 0 Ubiquitin-specific protease C-terminal DUF687 PF05095.7 ETO21251.1 - 0.063 11.6 0.5 0.067 11.5 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF687) HTH_43 PF09904.4 ETO21251.1 - 0.11 12.3 0.3 0.16 11.7 0.2 1.3 1 0 0 1 1 1 0 Winged helix-turn helix CPSase_L_D3 PF02787.14 ETO21251.1 - 0.28 10.9 3.7 4.1 7.1 0.6 2.1 1 1 1 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Exo_endo_phos PF03372.18 ETO21252.1 - 1.7e-20 74.0 0.1 3.3e-20 73.0 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HD-ZIP_N PF04618.7 ETO21253.1 - 0.67 10.5 6.9 0.36 11.3 3.1 1.8 1 1 1 2 2 2 0 HD-ZIP protein N terminus WD40 PF00400.27 ETO21254.1 - 4e-12 45.5 4.7 0.00052 19.8 0.0 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat PD40 PF07676.7 ETO21254.1 - 0.0024 17.4 0.0 2.3 7.9 0.0 2.5 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Apc4_WD40 PF12894.2 ETO21254.1 - 0.0047 16.3 0.0 13 5.4 0.0 3.8 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.2 ETO21254.1 - 0.013 15.2 0.2 0.043 13.5 0.0 2.0 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term SOBP PF15279.1 ETO21254.1 - 0.26 11.6 5.2 0.42 10.9 3.6 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2149 PF09919.4 ETO21255.1 - 1.6 8.8 0.0 1.6 8.8 0.0 3.2 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2149) GAGA_bind PF06217.7 ETO21256.1 - 3.1 7.6 10.7 4 7.3 7.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family MRP-S26 PF14943.1 ETO21256.1 - 7.8 6.0 21.3 15 5.0 14.8 1.4 1 1 0 1 1 1 0 Mitochondrial ribosome subunit S26 Ank_2 PF12796.2 ETO21257.1 - 5.9e-40 135.4 9.7 2.2e-11 43.9 0.0 5.2 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO21257.1 - 4.3e-38 129.0 9.2 9.3e-10 38.7 0.0 6.3 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 ETO21257.1 - 3.7e-32 108.5 5.2 5.9e-06 25.8 0.5 8.5 8 1 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.1 ETO21257.1 - 2e-29 100.9 7.3 2.7e-06 27.4 0.1 6.4 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO21257.1 - 1.6e-23 80.4 8.6 0.026 14.7 0.0 8.7 10 1 0 10 10 10 5 Ankyrin repeat PIG-U PF06728.8 ETO21259.1 - 6.1e-11 41.7 0.0 6.6e-11 41.6 0.0 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U S-methyl_trans PF02574.11 ETO21260.1 - 1.6e-20 73.6 0.0 2e-20 73.3 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase ENTH PF01417.15 ETO21261.1 - 0.00059 19.6 0.4 0.0012 18.6 0.3 1.6 1 0 0 1 1 1 1 ENTH domain PIP5K PF01504.13 ETO21262.1 - 2.2e-65 220.2 1.6 3.1e-65 219.7 1.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase NLBH PF05211.7 ETO21262.1 - 0.074 12.2 0.1 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) Kelch_4 PF13418.1 ETO21263.1 - 3.9e-07 29.7 0.5 0.0081 15.9 0.0 4.1 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO21263.1 - 1.5e-06 28.1 3.4 0.024 14.7 0.1 4.0 3 1 1 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO21263.1 - 1.6e-05 24.7 4.4 0.061 13.3 0.6 4.6 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.20 ETO21263.1 - 0.00016 21.1 5.3 0.016 14.7 0.2 4.0 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 ETO21263.1 - 0.00023 20.7 3.2 0.09 12.5 0.1 4.5 5 1 0 5 5 5 1 Kelch motif Kelch_3 PF13415.1 ETO21263.1 - 0.019 15.1 0.1 0.28 11.4 0.0 2.9 3 0 0 3 3 3 0 Galactose oxidase, central domain Viral_DNA_Zn_bi PF03728.8 ETO21264.1 - 0.039 14.0 0.1 0.061 13.4 0.1 1.3 1 0 0 1 1 1 0 Viral DNA-binding protein, zinc binding domain HDNR PF15115.1 ETO21264.1 - 0.59 10.0 5.4 3.1 7.7 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function with conserved HDNR motif Pkinase PF00069.20 ETO21266.1 - 3.8e-31 108.1 0.1 5.4e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO21266.1 - 3.2e-08 32.9 0.2 6.7e-08 31.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 ETO21266.1 - 0.00085 19.1 0.1 0.0038 16.9 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family V-ATPase_H_N PF03224.9 ETO21266.1 - 0.0048 16.0 0.1 0.0068 15.5 0.1 1.1 1 0 0 1 1 1 1 V-ATPase subunit H Choline_kinase PF01633.15 ETO21266.1 - 0.0069 15.9 0.2 0.02 14.4 0.0 1.8 2 1 0 2 2 2 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.12 ETO21267.1 - 5.4e-58 196.0 0.0 4e-51 173.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 ETO21267.1 - 7.3e-41 140.0 0.0 2.2e-40 138.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain IncA PF04156.9 ETO21267.1 - 8.1e-05 22.3 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 IncA protein V_ATPase_I PF01496.14 ETO21268.1 - 1.3e-169 565.6 12.1 1.6e-169 565.3 8.4 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF1363 PF07101.6 ETO21268.1 - 0.027 14.5 0.1 0.46 10.5 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1363) Pkinase PF00069.20 ETO21271.1 - 0.00077 18.6 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF2360 PF10152.4 ETO21273.1 - 0.028 14.6 0.2 0.049 13.9 0.1 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Acyl-thio_N PF12590.3 ETO21273.1 - 0.44 11.0 3.5 0.93 9.9 2.1 1.7 1 1 0 1 1 1 0 Acyl-ATP thioesterase Macoilin PF09726.4 ETO21273.1 - 0.51 8.5 4.1 0.52 8.5 2.8 1.1 1 0 0 1 1 1 0 Transmembrane protein CENP-B_dimeris PF09026.5 ETO21273.1 - 0.72 10.1 21.6 4.3 7.6 2.6 3.2 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Hid1 PF12722.2 ETO21273.1 - 2 6.0 9.6 2.6 5.6 6.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein HAP1_N PF04849.8 ETO21274.1 - 0.00014 20.8 8.0 0.00014 20.8 5.6 1.4 2 0 0 2 2 2 1 HAP1 N-terminal conserved region DUF812 PF05667.6 ETO21274.1 - 0.00038 19.1 5.2 0.00038 19.1 3.6 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF812) HALZ PF02183.13 ETO21274.1 - 0.0011 18.6 3.5 0.0011 18.6 2.4 2.6 1 1 1 2 2 2 1 Homeobox associated leucine zipper bZIP_1 PF00170.16 ETO21274.1 - 0.018 14.9 4.7 0.018 14.9 3.2 3.1 3 1 1 4 4 3 0 bZIP transcription factor DivIC PF04977.10 ETO21274.1 - 0.023 14.1 2.1 0.023 14.1 1.4 2.9 2 1 1 3 3 2 0 Septum formation initiator RTBV_P46 PF06216.6 ETO21274.1 - 0.046 12.5 1.1 0.068 12.0 0.8 1.3 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein RmuC PF02646.11 ETO21274.1 - 0.055 12.3 8.2 0.097 11.4 5.7 1.4 1 0 0 1 1 1 0 RmuC family Reo_sigmaC PF04582.7 ETO21274.1 - 0.23 10.5 1.5 0.38 9.8 1.1 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF948 PF06103.6 ETO21274.1 - 0.37 10.6 5.8 0.44 10.4 2.8 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) TBPIP PF07106.8 ETO21274.1 - 0.98 8.9 19.0 0.054 13.0 9.1 1.8 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Striatin PF08232.7 ETO21274.1 - 1.3 9.3 17.4 0.1 12.9 7.1 2.2 2 0 0 2 2 2 0 Striatin family Herpes_BLRF2 PF05812.7 ETO21274.1 - 1.6 8.5 13.9 0.57 9.9 6.2 2.3 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein Spc24 PF08286.6 ETO21274.1 - 1.8 8.2 21.0 0.22 11.2 2.6 2.7 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 AAA_23 PF13476.1 ETO21274.1 - 3.2 8.0 19.3 10 6.3 13.4 1.7 1 1 0 1 1 1 0 AAA domain ATG16 PF08614.6 ETO21274.1 - 4.3 7.1 19.0 0.42 10.3 8.6 2.2 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF4140 PF13600.1 ETO21274.1 - 4.4 7.8 9.3 6.8 7.2 0.7 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Macoilin PF09726.4 ETO21274.1 - 4.6 5.3 13.9 6.5 4.9 9.6 1.3 1 1 0 1 1 1 0 Transmembrane protein ADIP PF11559.3 ETO21274.1 - 5.5 6.8 23.5 0.38 10.6 4.7 2.9 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 ETO21274.1 - 5.6 5.9 15.0 0.46 9.4 7.0 1.7 2 0 0 2 2 2 0 Autophagy protein Apg6 Prefoldin PF02996.12 ETO21274.1 - 5.6 6.6 14.7 2.6 7.7 2.2 2.4 1 1 1 2 2 2 0 Prefoldin subunit HABP4_PAI-RBP1 PF04774.10 ETO21274.1 - 6.3 7.3 16.2 0.31 11.5 6.0 2.3 2 1 0 2 2 2 0 Hyaluronan / mRNA binding family TSC22 PF01166.13 ETO21274.1 - 8 6.5 11.2 0.3 11.0 2.5 2.5 2 1 1 3 3 3 0 TSC-22/dip/bun family VWA_2 PF13519.1 ETO21275.1 - 7.3e-09 35.9 0.0 9.6e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain SecA_DEAD PF07517.9 ETO21276.1 - 2.1e-08 33.7 0.0 2.1e-08 33.7 0.0 5.0 3 1 1 4 4 4 1 SecA DEAD-like domain ABC_tran PF00005.22 ETO21276.1 - 0.0015 18.8 0.0 0.0015 18.8 0.0 5.3 6 0 0 6 6 6 1 ABC transporter AAA_29 PF13555.1 ETO21276.1 - 0.0071 15.8 0.1 0.024 14.1 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 ETO21276.1 - 0.013 15.4 2.8 2.6 8.0 0.0 3.5 3 0 0 3 3 3 0 AAA ATPase domain AAA_19 PF13245.1 ETO21276.1 - 0.047 13.4 1.2 0.25 11.1 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain Usp PF00582.21 ETO21276.1 - 6.9 6.8 7.0 0.28 11.3 0.2 2.1 2 0 0 2 2 2 0 Universal stress protein family Pkinase PF00069.20 ETO21277.1 - 5.2e-09 35.6 14.4 5e-07 29.1 0.0 4.6 5 0 0 5 5 5 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO21277.1 - 4.3e-07 29.2 0.0 0.00087 18.4 0.0 3.1 3 1 0 3 3 3 2 Protein tyrosine kinase SR-25 PF10500.4 ETO21277.1 - 0.26 10.7 24.2 0.77 9.1 10.0 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein PGA2 PF07543.7 ETO21277.1 - 0.61 9.8 17.0 0.33 10.7 9.1 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 DUF1510 PF07423.6 ETO21277.1 - 3.6 6.9 34.9 2.7 7.3 16.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Menin PF05053.8 ETO21277.1 - 5.6 5.0 26.1 3.8 5.5 1.8 2.5 2 0 0 2 2 2 0 Menin DUF4131 PF13567.1 ETO21278.1 - 0.12 11.7 0.4 0.19 11.0 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Peptidase_M41 PF01434.13 ETO21279.1 - 3.4e-38 131.2 0.1 3.4e-38 131.2 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M41 polyprenyl_synt PF00348.12 ETO21279.1 - 0.066 12.0 7.2 0.081 11.7 5.0 1.3 1 0 0 1 1 1 0 Polyprenyl synthetase CobT PF06213.7 ETO21279.1 - 0.1 11.7 10.2 0.12 11.5 7.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DDHD PF02862.12 ETO21279.1 - 0.96 9.1 8.7 1.1 8.9 6.0 1.2 1 0 0 1 1 1 0 DDHD domain SAPS PF04499.10 ETO21279.1 - 3.4 6.2 12.4 4.1 5.9 8.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein LacI PF00356.16 ETO21280.1 - 0.04 13.5 0.1 0.098 12.2 0.1 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family B2-adapt-app_C PF09066.5 ETO21281.1 - 5.7e-09 35.8 0.0 1.1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain Pkinase PF00069.20 ETO21282.1 - 1.2e-11 44.3 0.2 1.6e-05 24.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO21282.1 - 0.00015 20.9 0.6 0.15 11.1 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Hus1 PF04005.7 ETO21283.1 - 9.8e-27 93.6 5.2 9.8e-27 93.6 3.6 3.5 2 1 0 2 2 2 1 Hus1-like protein DUF2682 PF10909.3 ETO21283.1 - 0.041 14.1 1.7 0.23 11.7 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2682) Rad9 PF04139.8 ETO21283.1 - 0.097 11.7 4.9 1.2 8.2 3.4 2.2 1 1 0 1 1 1 0 Rad9 DUF809 PF05663.6 ETO21283.1 - 0.1 12.5 1.4 0.51 10.2 0.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF809) adh_short PF00106.20 ETO21285.1 - 1.4e-16 60.8 0.0 1.9e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETO21285.1 - 2.9e-08 33.6 0.1 4.1e-08 33.0 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF981 PF06168.6 ETO21285.1 - 0.032 14.0 0.9 0.062 13.0 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF981) CENP-M PF11111.3 ETO21285.1 - 0.038 13.2 0.2 0.34 10.1 0.1 2.3 1 1 2 3 3 3 0 Centromere protein M (CENP-M) RGS PF00615.14 ETO21286.1 - 0.0021 18.1 0.4 0.0044 17.1 0.3 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF4042 PF13251.1 ETO21287.1 - 8e-08 31.9 4.7 1.5e-06 27.8 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF4042) RIX1 PF08167.7 ETO21287.1 - 0.0081 15.8 3.5 0.049 13.3 0.0 2.8 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis HEAT PF02985.17 ETO21287.1 - 0.055 13.5 0.4 1.1 9.5 0.0 3.3 4 0 0 4 4 4 0 HEAT repeat RCC1 PF00415.13 ETO21288.1 - 6.5e-06 26.2 0.0 0.13 12.5 0.0 2.3 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO21288.1 - 3.2 7.5 4.4 50 3.6 0.1 3.2 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 ETO21289.1 - 4.7e-23 81.1 0.3 2.3e-12 46.8 0.1 3.3 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO21289.1 - 6.8e-19 66.9 7.0 1.5e-09 37.2 0.5 2.4 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 ETO21289.1 - 0.13 11.7 1.3 8.4 5.9 0.1 2.4 2 1 0 2 2 2 0 Putative carbohydrate binding domain Ras PF00071.17 ETO21290.1 - 2.1e-19 69.4 1.1 3.3e-19 68.8 0.8 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO21290.1 - 1.4e-09 38.4 0.6 2.6e-09 37.6 0.2 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO21290.1 - 0.0045 16.2 1.0 0.0068 15.6 0.4 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family RRM_1 PF00076.17 ETO21291.1 - 5.3e-05 22.7 0.0 0.00012 21.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO21291.1 - 0.00017 21.4 0.0 0.00034 20.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Herpes_UL4 PF03277.8 ETO21291.1 - 0.06 12.5 3.1 0.12 11.6 2.2 1.6 1 0 0 1 1 1 0 Herpesvirus UL4 family Pneumo_NS1 PF03438.8 ETO21292.1 - 0.025 14.3 2.8 3.6 7.4 0.1 2.8 3 0 0 3 3 3 0 Pneumovirus NS1 protein DnaJ PF00226.26 ETO21293.1 - 4.1e-20 71.2 1.3 6e-20 70.7 0.9 1.3 1 0 0 1 1 1 1 DnaJ domain Rotamase_2 PF13145.1 ETO21293.1 - 0.0055 17.3 2.3 0.0061 17.1 1.6 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain RPT PF13446.1 ETO21293.1 - 0.025 14.0 0.0 0.13 11.6 0.0 1.9 1 1 1 2 2 2 0 A repeated domain in UCH-protein Fe-ADH PF00465.14 ETO21294.1 - 0.0033 16.1 0.0 0.004 15.8 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 ETO21294.1 - 0.075 12.3 0.0 0.093 12.0 0.0 1.1 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.14 ETO21295.1 - 3.3e-22 78.6 0.0 3.5e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 ETO21295.1 - 2.7e-09 36.6 0.0 3.2e-09 36.4 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DUF2661 PF10860.3 ETO21296.1 - 0.17 12.0 3.4 0.2 11.8 1.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2661) G-alpha PF00503.15 ETO21297.1 - 1.9e-19 69.6 2.0 2.1e-19 69.4 1.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit YqzE PF14038.1 ETO21298.1 - 0.26 11.0 6.2 0.4 10.4 4.3 1.2 1 0 0 1 1 1 0 YqzE-like protein Protocadherin PF08374.6 ETO21298.1 - 2.2 7.8 7.9 8.4 5.9 0.1 2.0 2 0 0 2 2 2 0 Protocadherin BLVR PF06375.6 ETO21298.1 - 2.8 7.7 7.0 3.6 7.4 4.9 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) RNase_H2-Ydr279 PF09468.5 ETO21298.1 - 8.3 5.5 7.8 12 4.9 5.4 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) CENP-B_dimeris PF09026.5 ETO21299.1 - 0.04 14.1 7.3 0.061 13.5 5.1 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TRAP_alpha PF03896.11 ETO21299.1 - 0.066 12.2 0.2 0.11 11.4 0.2 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit VID27 PF08553.5 ETO21299.1 - 0.65 8.1 6.2 0.83 7.7 4.3 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF912 PF06024.7 ETO21299.1 - 1.1 9.3 5.5 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Dishevelled PF02377.10 ETO21300.1 - 0.01 16.0 2.5 0.056 13.6 1.7 2.3 1 0 0 1 1 1 0 Dishevelled specific domain Mucin PF01456.12 ETO21300.1 - 0.025 14.3 19.9 0.13 12.0 1.7 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein Prog_receptor PF02161.10 ETO21300.1 - 0.1 11.3 3.9 0.2 10.4 2.7 1.8 1 0 0 1 1 1 0 Progesterone receptor Coat_X PF07552.6 ETO21300.1 - 5.5 6.8 14.1 0.14 11.9 2.6 2.6 2 0 0 2 2 2 0 Spore Coat Protein X and V domain PPR_2 PF13041.1 ETO21301.1 - 1.6e-08 34.4 8.5 2e-07 30.8 1.2 3.1 3 1 0 3 3 3 2 PPR repeat family PPR PF01535.15 ETO21301.1 - 0.0082 16.0 0.7 0.0082 16.0 0.5 3.9 5 0 0 5 5 5 1 PPR repeat PPR_1 PF12854.2 ETO21301.1 - 0.09 12.2 0.5 3.3 7.2 0.0 3.0 2 0 0 2 2 2 0 PPR repeat Ribonuc_red_lgN PF00317.16 ETO21301.1 - 0.18 11.6 2.9 7 6.5 2.1 3.0 1 1 1 2 2 2 0 Ribonucleotide reductase, all-alpha domain Apc3 PF12895.2 ETO21301.1 - 0.31 11.2 8.1 0.096 12.8 1.3 2.9 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF1675 PF07897.6 ETO21302.1 - 9 6.0 13.2 11 5.7 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) TPR_11 PF13414.1 ETO21303.1 - 9.8e-16 57.1 5.0 5.1e-14 51.6 0.8 2.3 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETO21303.1 - 2.9e-14 51.9 8.4 5.1e-08 32.1 0.7 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO21303.1 - 7.4e-12 44.2 4.0 1.3e-05 24.7 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 ETO21303.1 - 7e-07 29.1 3.1 0.00019 21.2 0.2 2.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO21303.1 - 5.8e-05 22.5 3.3 0.011 15.5 0.1 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO21303.1 - 0.0025 18.1 0.6 0.022 15.0 0.1 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO21303.1 - 0.0029 17.6 6.7 0.0029 17.6 0.3 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO21303.1 - 0.0042 17.7 0.2 0.081 13.6 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO21303.1 - 0.0059 16.7 5.7 0.026 14.6 3.2 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 ETO21303.1 - 0.023 15.2 0.0 0.74 10.6 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat SNAP PF14938.1 ETO21303.1 - 0.045 12.8 3.1 0.52 9.4 2.2 2.2 1 1 0 1 1 1 0 Soluble NSF attachment protein, SNAP DUF3079 PF11278.3 ETO21305.1 - 0.27 10.7 3.6 0.46 10.0 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3079) DUF2457 PF10446.4 ETO21306.1 - 0.0094 14.7 16.8 0.0097 14.6 11.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Pox_Ag35 PF03286.9 ETO21306.1 - 0.015 14.8 9.8 0.014 14.9 6.8 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Adaptin_binding PF10199.4 ETO21306.1 - 0.02 15.1 9.0 0.021 15.1 6.2 1.1 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Methyltransf_12 PF08242.7 ETO21306.1 - 0.17 12.3 0.6 0.19 12.1 0.4 1.3 1 0 0 1 1 1 0 Methyltransferase domain RAB3GAP2_C PF14656.1 ETO21306.1 - 0.18 9.9 2.3 0.21 9.6 1.6 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Tim54 PF11711.3 ETO21306.1 - 0.26 9.8 7.0 0.29 9.6 4.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF3449 PF11931.3 ETO21306.1 - 0.27 10.7 9.1 0.33 10.4 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Daxx PF03344.10 ETO21306.1 - 0.32 9.4 17.0 0.32 9.4 11.8 1.0 1 0 0 1 1 1 0 Daxx Family RR_TM4-6 PF06459.7 ETO21306.1 - 0.49 10.2 6.5 0.66 9.8 4.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BUD22 PF09073.5 ETO21306.1 - 0.62 9.0 14.3 0.65 8.9 9.9 1.0 1 0 0 1 1 1 0 BUD22 CDC27 PF09507.5 ETO21306.1 - 0.93 8.6 11.2 0.92 8.6 7.8 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Vfa1 PF08432.5 ETO21306.1 - 1.2 9.1 11.0 1.3 9.0 7.6 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TRAP_alpha PF03896.11 ETO21306.1 - 1.4 7.8 9.3 1.4 7.8 6.4 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FYDLN_acid PF09538.5 ETO21306.1 - 1.6 9.3 16.8 1.9 9.0 11.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Astro_capsid PF03115.9 ETO21306.1 - 1.8 6.6 10.3 2.1 6.5 7.1 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor CDC45 PF02724.9 ETO21306.1 - 2 6.3 15.6 2.5 6.0 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.7 ETO21306.1 - 2.1 7.9 17.9 2.5 7.7 12.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 ETO21306.1 - 2.1 6.1 18.7 2.2 6.0 13.0 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_pol_3_Rpc31 PF11705.3 ETO21306.1 - 2.9 7.7 21.0 3.6 7.4 14.6 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TLP-20 PF06088.6 ETO21306.1 - 3.3 7.3 11.1 4.2 7.0 7.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Rhabdo_ncap PF00945.13 ETO21306.1 - 4.2 5.8 6.4 4.6 5.7 4.4 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein RRN3 PF05327.6 ETO21306.1 - 4.3 5.3 7.5 4.3 5.3 5.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ycf1 PF05758.7 ETO21306.1 - 4.8 4.7 6.6 5 4.7 4.6 1.0 1 0 0 1 1 1 0 Ycf1 SDA1 PF05285.7 ETO21306.1 - 8.1 5.6 18.5 8.8 5.5 12.8 1.1 1 0 0 1 1 1 0 SDA1 DUF1510 PF07423.6 ETO21306.1 - 9.4 5.5 18.9 11 5.2 13.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF1230 PF06799.6 ETO21307.1 - 0.061 13.1 0.4 9.5 6.0 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1230) GNAT_acetyltr_2 PF13718.1 ETO21307.1 - 0.12 11.7 0.3 0.2 10.9 0.2 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 RGS PF00615.14 ETO21309.1 - 1.6e-10 41.0 0.1 2.2e-10 40.6 0.1 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain eRF1_2 PF03464.10 ETO21313.1 - 3.4e-26 92.1 1.5 9.4e-25 87.4 1.0 2.4 1 1 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 ETO21313.1 - 4.7e-18 65.5 0.1 1.3e-17 64.0 0.0 1.8 1 0 0 1 1 1 1 eRF1 domain 3 Pkinase PF00069.20 ETO21314.1 - 1.1e-60 204.9 0.2 1.4e-60 204.6 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO21314.1 - 6.6e-42 143.3 0.1 8.1e-42 143.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO21314.1 - 2.5e-07 29.9 0.0 3.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETO21314.1 - 0.0001 21.4 0.2 0.00018 20.6 0.2 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO21314.1 - 0.00048 19.9 0.1 0.00088 19.0 0.0 1.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 ETO21314.1 - 0.0064 16.0 0.0 0.0082 15.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 ETO21314.1 - 0.0066 15.8 0.0 0.028 13.7 0.0 1.9 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 ETO21314.1 - 0.013 14.9 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 RIO1 family ATS PF15445.1 ETO21314.1 - 0.034 13.2 0.0 0.047 12.8 0.0 1.1 1 0 0 1 1 1 0 acidic terminal segments, variant surface antigen of PfEMP1 YukC PF10140.4 ETO21314.1 - 0.06 11.9 0.0 0.086 11.3 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Seadorna_VP7 PF07387.6 ETO21314.1 - 0.093 11.5 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 UPF0118 PF01594.11 ETO21315.1 - 2.5e-33 115.4 14.8 2.5e-33 115.4 10.2 1.4 2 0 0 2 2 2 1 Domain of unknown function DUF20 DUF2312 PF10073.4 ETO21315.1 - 6.7e-30 102.2 5.4 1.3e-29 101.3 3.7 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2312) RPAP3_C PF13877.1 ETO21315.1 - 0.016 15.1 1.1 3.8 7.5 0.3 2.7 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 CPSase_L_D3 PF02787.14 ETO21315.1 - 0.11 12.2 1.0 0.23 11.2 0.7 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain RCC1 PF00415.13 ETO21316.1 - 2.3e-09 37.3 0.0 0.0018 18.4 0.0 3.5 3 1 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO21316.1 - 2.2e-08 33.4 0.2 7.6e-07 28.5 0.1 2.9 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat Chordopox_G3 PF06129.7 ETO21318.1 - 0.22 11.6 2.0 0.24 11.5 0.5 1.6 2 0 0 2 2 2 0 Chordopoxvirus G3 protein Ank_2 PF12796.2 ETO21319.1 - 2.1e-22 79.2 2.0 1.4e-12 47.7 0.0 4.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETO21319.1 - 4.6e-14 51.4 8.0 1.9e-06 27.3 0.0 5.4 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.1 ETO21319.1 - 2e-12 46.0 8.4 7.4e-05 22.6 0.0 5.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 ETO21319.1 - 6.4e-12 45.6 4.9 2.7e-05 24.5 0.1 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO21319.1 - 4.5e-06 26.7 0.3 4.5e-06 26.7 0.2 4.9 4 2 2 6 6 6 2 Ankyrin repeats (many copies) DUF4611 PF15387.1 ETO21319.1 - 0.00092 19.3 2.0 0.00092 19.3 1.4 3.2 2 1 1 3 3 3 1 Domain of unknown function (DUF4611) EVI2A PF05399.6 ETO21319.1 - 0.22 10.7 7.5 0.48 9.6 5.2 1.5 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) TRAP_alpha PF03896.11 ETO21319.1 - 0.23 10.4 12.4 0.15 11.0 3.3 2.5 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Nucleoplasmin PF03066.10 ETO21319.1 - 6.9 6.1 21.4 0.65 9.5 3.2 2.6 2 0 0 2 2 2 0 Nucleoplasmin DSHCT PF08148.7 ETO21320.1 - 1.4e-46 157.9 1.3 1.6e-45 154.6 0.1 2.6 2 1 0 2 2 2 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.1 ETO21320.1 - 3.9e-33 114.7 0.4 1.3e-32 113.0 0.3 1.9 1 1 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.26 ETO21320.1 - 9.8e-08 31.7 0.0 3.5e-07 29.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain NPV_P10 PF05531.7 ETO21320.1 - 0.29 11.4 3.8 8.1 6.7 0.4 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1336 PF07059.7 ETO21321.1 - 4.6e-17 62.2 3.4 4.7e-14 52.3 0.0 3.7 2 2 1 3 3 3 3 Protein of unknown function (DUF1336) TRAM_LAG1_CLN8 PF03798.11 ETO21322.1 - 2.3e-23 82.8 32.7 3.1e-23 82.3 22.7 1.2 1 0 0 1 1 1 1 TLC domain NACHT PF05729.7 ETO21323.1 - 1.4e-14 54.1 0.0 4.8e-14 52.3 0.0 2.1 1 0 0 1 1 1 1 NACHT domain HEAT_2 PF13646.1 ETO21323.1 - 1.3e-07 31.8 0.0 0.47 10.7 0.0 5.8 2 2 5 7 7 7 3 HEAT repeats HEAT PF02985.17 ETO21323.1 - 6.7e-07 28.8 1.3 33 4.9 0.0 8.7 9 0 0 9 9 9 0 HEAT repeat Ank_5 PF13857.1 ETO21323.1 - 5.8e-06 26.3 0.0 2.1e-05 24.5 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 ETO21323.1 - 8.4e-06 25.3 0.1 4.5e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 ETO21323.1 - 0.00021 21.2 0.0 0.0022 18.0 0.0 2.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 ETO21323.1 - 0.0017 18.6 1.5 0.0053 17.0 0.0 2.8 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) AAA_16 PF13191.1 ETO21323.1 - 0.0053 16.7 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.16 ETO21323.1 - 0.031 13.4 0.0 0.09 11.9 0.0 1.7 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 ETO21323.1 - 0.033 13.5 0.0 0.077 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 ETO21323.1 - 0.17 12.0 0.1 0.17 12.0 0.0 3.6 4 1 0 4 4 4 0 AAA domain HEAT_EZ PF13513.1 ETO21323.1 - 0.18 12.3 0.0 38 4.9 0.0 4.5 4 0 0 4 4 4 0 HEAT-like repeat FYVE PF01363.16 ETO21324.1 - 1.9e-09 37.2 8.1 3.9e-09 36.2 5.6 1.5 1 0 0 1 1 1 1 FYVE zinc finger A2L_zn_ribbon PF08792.5 ETO21324.1 - 0.015 14.7 4.6 0.21 11.0 0.5 2.6 2 0 0 2 2 2 0 A2L zinc ribbon domain CDC45 PF02724.9 ETO21324.1 - 0.12 10.4 2.1 0.11 10.5 1.5 1.1 1 0 0 1 1 1 0 CDC45-like protein IBR PF01485.16 ETO21324.1 - 0.55 10.1 12.4 0.11 12.3 4.7 2.3 1 1 1 2 2 2 0 IBR domain zf-B_box PF00643.19 ETO21324.1 - 0.57 10.1 9.6 0.31 10.9 3.5 2.4 2 0 0 2 2 2 0 B-box zinc finger zf-RING_4 PF14570.1 ETO21324.1 - 0.63 9.6 9.9 0.74 9.4 6.1 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 ETO21324.1 - 0.86 9.3 9.9 1.7 8.4 6.9 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DUF2201_N PF13203.1 ETO21324.1 - 1.1 8.3 4.8 1.3 8.0 3.3 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain B5 PF03484.10 ETO21325.1 - 0.031 14.1 0.4 1 9.2 0.2 2.4 1 1 0 1 1 1 0 tRNA synthetase B5 domain UPF0180 PF03698.8 ETO21325.1 - 0.059 13.2 0.1 0.098 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) Spc7 PF08317.6 ETO21326.1 - 0.0045 15.6 6.2 0.0045 15.6 4.3 2.1 1 1 1 2 2 2 1 Spc7 kinetochore protein Crp PF00325.15 ETO21326.1 - 0.11 12.0 0.1 0.22 11.0 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family DUF2358 PF10184.4 ETO21326.1 - 1.8 8.5 7.8 0.51 10.2 0.2 3.1 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2358) Guanylate_cyc PF00211.15 ETO21327.1 - 5.2e-26 91.1 3.5 1e-25 90.1 2.4 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain MutS_III PF05192.13 ETO21328.1 - 7.9e-13 48.6 0.4 2.2e-12 47.1 0.1 1.8 1 1 0 1 1 1 1 MutS domain III MutS_II PF05188.12 ETO21328.1 - 0.0001 22.4 0.1 0.00092 19.2 0.0 2.5 1 1 0 1 1 1 1 MutS domain II DUF2451 PF10474.4 ETO21329.1 - 3.5e-29 102.2 0.1 1.2e-28 100.4 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) DUF3510 PF12022.3 ETO21329.1 - 0.036 14.1 0.2 0.082 13.0 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) DUF3080 PF11279.3 ETO21329.1 - 0.042 12.9 0.5 0.1 11.7 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3080) BRK PF07533.11 ETO21329.1 - 0.095 12.1 1.0 0.2 11.1 0.2 1.8 2 0 0 2 2 2 0 BRK domain Sulfate_transp PF00916.15 ETO21330.1 - 9.4e-36 123.2 11.0 1.2e-34 119.6 7.0 2.4 1 1 0 1 1 1 1 Sulfate transporter family STAS PF01740.16 ETO21330.1 - 7.5e-10 38.2 0.0 1.3e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain DUF3577 PF12101.3 ETO21331.1 - 0.092 12.6 0.2 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3577) TRH PF05438.7 ETO21332.1 - 0.014 14.8 0.6 0.019 14.3 0.4 1.2 1 0 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) MxiM PF11441.3 ETO21334.1 - 0.019 15.0 0.2 0.043 13.8 0.1 1.5 1 0 0 1 1 1 0 Pilot protein MxiM Cation_ATPase_C PF00689.16 ETO21334.1 - 0.022 14.3 16.4 0.017 14.6 3.3 2.2 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus DUF3619 PF12279.3 ETO21334.1 - 1.3 9.1 3.8 0.74 9.8 0.1 2.4 2 2 0 2 2 2 0 Protein of unknown function (DUF3619) DUF4247 PF14042.1 ETO21335.1 - 0.0062 16.5 1.6 0.0097 15.8 1.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4247) Med15 PF09606.5 ETO21335.1 - 0.025 12.7 15.0 0.021 13.0 10.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MotA_ExbB PF01618.11 ETO21335.1 - 0.71 9.4 2.4 1.5 8.4 1.6 1.5 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family RNase_T PF00929.19 ETO21336.1 - 1.6e-09 38.3 0.4 1.6e-09 38.3 0.3 1.8 2 0 0 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.15 ETO21336.1 - 0.00052 19.5 0.4 0.0013 18.2 0.1 1.8 2 0 0 2 2 2 1 3'-5' exonuclease LexA_DNA_bind PF01726.11 ETO21336.1 - 0.03 13.8 0.0 1.3 8.5 0.0 2.5 2 0 0 2 2 2 0 LexA DNA binding domain DEP PF00610.16 ETO21337.1 - 4.4e-10 39.1 0.1 9.1e-10 38.1 0.1 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF2457 PF10446.4 ETO21337.1 - 0.0093 14.7 30.1 0.014 14.1 20.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Daxx PF03344.10 ETO21337.1 - 0.026 13.0 19.8 0.03 12.8 13.8 1.1 1 0 0 1 1 1 0 Daxx Family Hid1 PF12722.2 ETO21337.1 - 0.11 10.1 13.6 0.15 9.7 9.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein IncA PF04156.9 ETO21337.1 - 0.2 11.2 0.9 0.33 10.5 0.6 1.3 1 0 0 1 1 1 0 IncA protein DUF605 PF04652.11 ETO21337.1 - 3.6 6.8 16.1 4.8 6.4 11.2 1.2 1 0 0 1 1 1 0 Vta1 like Plasmodium_Vir PF05795.6 ETO21338.1 - 0.0064 15.7 0.1 0.011 14.9 0.0 1.5 2 0 0 2 2 2 1 Plasmodium vivax Vir protein Acyl-CoA_dh_1 PF00441.19 ETO21339.1 - 4.8e-41 140.3 0.7 6.3e-41 139.9 0.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 ETO21339.1 - 4.4e-17 62.6 0.0 1.1e-16 61.4 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 ETO21339.1 - 6.2e-17 60.8 0.0 1.1e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 ETO21339.1 - 2.3e-07 31.1 0.0 3.6e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SIT PF15330.1 ETO21340.1 - 0.014 15.5 0.8 0.068 13.3 0.6 2.1 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Gemini_AC4_5_2 PF08464.5 ETO21340.1 - 0.092 12.4 0.1 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region DUF2457 PF10446.4 ETO21340.1 - 0.29 9.8 9.4 0.48 9.0 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 ETO21340.1 - 1.5 6.6 5.0 1.6 6.5 3.5 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.5 ETO21340.1 - 2.2 8.5 9.2 5.2 7.3 6.4 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TIM21 PF08294.6 ETO21343.1 - 5.2e-05 22.9 12.1 5.5e-05 22.8 0.1 2.9 4 0 0 4 4 4 2 TIM21 Coa1 PF08695.5 ETO21343.1 - 0.022 14.2 0.6 0.056 12.9 0.0 2.0 2 1 1 3 3 3 0 Cytochrome oxidase complex assembly protein 1 SpoIISB_antitox PF14185.1 ETO21343.1 - 0.032 13.9 0.2 0.11 12.2 0.1 1.9 1 0 0 1 1 1 0 Antitoxin SpoIISB, type II toxin-antitoxin system DUF4481 PF14800.1 ETO21343.1 - 0.071 12.0 3.4 4.3 6.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4481) DDHD PF02862.12 ETO21343.1 - 0.48 10.1 8.2 0.74 9.5 5.7 1.2 1 0 0 1 1 1 0 DDHD domain DUF3816 PF12822.2 ETO21344.1 - 0.0036 17.2 6.2 0.033 14.1 0.2 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3816) ENTH PF01417.15 ETO21344.1 - 0.022 14.6 0.2 0.033 14.0 0.1 1.3 1 0 0 1 1 1 0 ENTH domain FAM176 PF14851.1 ETO21344.1 - 0.068 12.8 0.0 0.068 12.8 0.0 1.7 2 0 0 2 2 2 0 FAM176 family DUF543 PF04418.7 ETO21344.1 - 0.13 12.2 0.6 1.8 8.5 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF543) PRA1 PF03208.14 ETO21344.1 - 0.73 9.1 7.7 5.8 6.2 4.0 2.3 2 0 0 2 2 2 0 PRA1 family protein Abhydrolase_9_N PF15420.1 ETO21344.1 - 0.83 9.3 4.1 3.6 7.2 0.4 2.0 1 1 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus DUF3439 PF11921.3 ETO21345.1 - 0.16 11.7 10.9 0.33 10.7 7.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 ETO21345.1 - 0.52 8.0 12.5 0.71 7.5 8.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.6 ETO21345.1 - 1.8 6.4 19.9 2.6 5.9 13.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 IBN_N PF03810.14 ETO21346.1 - 0.00013 21.8 6.4 0.00043 20.1 0.1 2.8 2 1 1 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 ETO21346.1 - 0.00037 20.7 0.2 0.00094 19.4 0.0 1.6 2 0 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.1 ETO21346.1 - 0.052 14.0 0.1 0.2 12.1 0.0 1.9 2 0 0 2 2 2 0 HEAT-like repeat Mito_carr PF00153.22 ETO21347.1 - 8.6e-11 41.3 4.6 0.00013 21.6 0.5 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein ArfGap PF01412.13 ETO21348.1 - 1.7e-30 105.1 0.4 5.2e-30 103.6 0.3 1.8 1 1 0 1 1 1 1 Putative GTPase activating protein for Arf Ank_2 PF12796.2 ETO21348.1 - 3.3e-08 33.7 0.0 7.1e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO21348.1 - 1.8e-07 30.6 0.4 2.7e-05 23.7 0.0 3.4 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.1 ETO21348.1 - 0.00038 20.5 0.0 0.001 19.2 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO21348.1 - 0.023 15.2 0.1 0.12 12.9 0.0 2.2 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO21348.1 - 0.13 12.5 0.3 0.95 9.9 0.0 2.6 3 0 0 3 3 3 0 Ankyrin repeat zf-RanBP PF00641.13 ETO21349.1 - 5.9e-06 25.2 27.3 0.00048 19.1 1.4 3.4 2 1 1 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.2 ETO21349.1 - 6e-05 22.7 20.8 0.0022 17.7 8.5 2.4 1 1 1 2 2 2 2 Double zinc ribbon BSP_II PF05432.6 ETO21349.1 - 0.028 13.6 13.6 0.06 12.6 9.4 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CDC27 PF09507.5 ETO21349.1 - 0.048 12.8 29.1 0.065 12.4 20.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RXT2_N PF08595.6 ETO21349.1 - 0.34 10.6 9.5 0.74 9.6 6.6 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 ETO21349.1 - 0.66 9.4 15.3 2.6 7.5 10.6 2.0 1 0 0 1 1 1 0 Nucleoplasmin DUF2413 PF10310.4 ETO21349.1 - 1.2 7.8 18.8 1.6 7.4 13.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) YlzJ PF14035.1 ETO21349.1 - 1.6 8.8 4.3 47 4.1 2.1 2.5 2 0 0 2 2 2 0 YlzJ-like protein PBP1_TM PF14812.1 ETO21349.1 - 1.7 8.9 16.7 0.24 11.7 8.1 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.1 ETO21349.1 - 4.5 6.9 14.3 0.47 10.1 6.7 1.8 2 0 0 2 2 2 0 FAM176 family RhoGAP PF00620.22 ETO21352.1 - 1.6e-09 37.5 0.0 2.1e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain RPEL PF02755.10 ETO21353.1 - 2.8e-10 39.1 59.5 5.7e-05 22.3 0.2 13.2 15 0 0 15 15 15 9 RPEL repeat DUF480 PF04337.7 ETO21354.1 - 0.052 13.3 0.4 0.1 12.4 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF480 AAA_25 PF13481.1 ETO21354.1 - 0.21 10.9 0.9 0.89 8.9 0.1 2.2 2 1 1 3 3 3 0 AAA domain DIL PF01843.14 ETO21355.1 - 0.12 12.2 1.0 0.19 11.6 0.1 1.8 2 0 0 2 2 2 0 DIL domain RNase_Zc3h12a PF11977.3 ETO21355.1 - 0.16 11.7 0.7 1.1 9.1 0.1 2.3 3 0 0 3 3 3 0 Zc3h12a-like Ribonuclease NYN domain Sterol_MT_C PF08498.5 ETO21356.1 - 1.7e-20 72.7 0.0 3e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 ETO21356.1 - 9.6e-15 54.8 0.0 2.2e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 ETO21356.1 - 2.9e-12 46.2 0.2 1.1e-11 44.3 0.1 1.9 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 ETO21356.1 - 6.9e-11 41.9 1.2 6.9e-10 38.7 0.9 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETO21356.1 - 5.7e-10 39.1 0.0 9.5e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO21356.1 - 4e-06 27.2 0.0 1.4e-05 25.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETO21356.1 - 0.00027 20.1 0.0 0.00043 19.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 ETO21356.1 - 0.00028 21.4 0.0 0.00081 19.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETO21356.1 - 0.00098 19.4 0.1 0.0028 17.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETO21356.1 - 0.053 13.5 0.0 0.14 12.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Hydrolase PF00702.21 ETO21357.1 - 8.2e-35 121.1 0.0 2.7e-29 103.1 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 ETO21357.1 - 3e-18 65.7 1.3 4.9e-18 65.0 0.9 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 ETO21357.1 - 9.7e-18 64.3 1.8 9.7e-18 64.3 1.3 2.2 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus HAD PF12710.2 ETO21357.1 - 7.1e-15 55.6 1.3 1.3e-13 51.5 0.9 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETO21357.1 - 4.7e-14 52.1 0.1 1e-13 51.0 0.1 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 ETO21357.1 - 4.9e-06 26.3 9.3 0.0015 18.1 1.3 3.3 4 0 0 4 4 4 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 ETO21357.1 - 0.003 17.8 0.0 0.0075 16.5 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 ETO21357.1 - 0.014 15.2 0.0 0.039 13.8 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Filament PF00038.16 ETO21358.1 - 0.00011 21.8 43.7 0.00011 21.8 30.3 4.4 1 1 2 4 4 4 3 Intermediate filament protein Reo_sigmaC PF04582.7 ETO21358.1 - 0.0033 16.6 3.6 0.0033 16.6 2.5 4.2 1 1 2 4 4 4 2 Reovirus sigma C capsid protein IncA PF04156.9 ETO21358.1 - 0.9 9.1 101.7 0.11 12.0 18.1 6.1 1 1 4 6 6 6 0 IncA protein PEP-utilisers_N PF05524.8 ETO21358.1 - 1 9.2 28.4 36 4.1 2.2 5.1 2 2 0 2 2 2 0 PEP-utilising enzyme, N-terminal WEMBL PF05701.6 ETO21358.1 - 4.9 5.5 102.2 0.12 10.7 25.0 3.6 2 1 1 3 3 3 0 Weak chloroplast movement under blue light LRR_6 PF13516.1 ETO21359.1 - 3.7e-05 23.3 4.8 0.002 17.9 0.0 4.5 5 0 0 5 5 5 1 Leucine Rich repeat LRR_4 PF12799.2 ETO21359.1 - 0.0014 18.2 4.0 0.011 15.4 0.1 3.5 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETO21359.1 - 0.016 15.1 3.6 69 4.0 0.0 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat DUF3764 PF12594.3 ETO21359.1 - 0.043 13.5 0.4 0.15 11.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3764) DUF3849 PF12960.2 ETO21360.1 - 0.074 13.0 2.7 0.13 12.2 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3849) DUF1476 PF07345.6 ETO21360.1 - 0.4 10.9 2.1 0.83 9.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1476) RXT2_N PF08595.6 ETO21360.1 - 2.7 7.7 8.5 0.57 9.9 0.3 2.6 3 0 0 3 3 3 0 RXT2-like, N-terminal EF-hand_8 PF13833.1 ETO21361.1 - 1.5e-05 24.4 15.4 0.022 14.3 1.1 4.4 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.27 ETO21361.1 - 3.1e-05 22.9 18.0 0.0065 15.6 0.6 4.6 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 ETO21361.1 - 0.00031 20.3 12.1 0.11 12.4 0.1 5.0 5 0 0 5 5 4 2 EF-hand domain EF-hand_7 PF13499.1 ETO21361.1 - 0.0014 18.6 18.1 0.073 13.2 0.0 5.3 4 1 1 5 5 5 2 EF-hand domain pair CENP-B_dimeris PF09026.5 ETO21361.1 - 0.027 14.6 22.7 0.33 11.2 14.5 3.2 3 0 0 3 3 3 0 Centromere protein B dimerisation domain CDC45 PF02724.9 ETO21361.1 - 0.029 12.4 10.2 0.062 11.3 7.0 1.6 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.5 ETO21361.1 - 0.39 10.7 10.9 0.14 12.1 5.0 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Neur_chan_memb PF02932.11 ETO21361.1 - 0.65 9.8 8.8 5.2 6.8 6.1 2.2 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2457 PF10446.4 ETO21361.1 - 1.4 7.5 33.8 0.038 12.7 18.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) ANAPC15 PF15243.1 ETO21361.1 - 1.6 8.8 23.6 0.2 11.7 12.1 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Vma12 PF11712.3 ETO21361.1 - 3 7.5 5.7 5.8 6.6 0.2 2.4 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase PBP1_TM PF14812.1 ETO21361.1 - 3.5 8.0 27.5 6.3 7.1 13.5 3.4 4 0 0 4 4 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4366 PF14283.1 ETO21361.1 - 4.5 6.6 16.3 12 5.2 10.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) DUF912 PF06024.7 ETO21361.1 - 5.4 7.1 11.7 0.2 11.7 1.4 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2201_N PF13203.1 ETO21361.1 - 6.1 5.9 7.2 0.7 9.0 1.6 1.8 2 0 0 2 2 2 0 Putative metallopeptidase domain DUF4448 PF14610.1 ETO21361.1 - 9.2 5.7 7.2 0.74 9.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) RasGEF_N PF00618.15 ETO21362.1 - 5.8e-07 29.5 0.0 1.7e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif ELFV_dehydrog PF00208.16 ETO21363.1 - 3.4e-22 79.2 0.4 4.1e-22 78.9 0.3 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 ETO21363.1 - 8.2e-20 70.7 0.0 1.2e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain CDC45 PF02724.9 ETO21364.1 - 0.002 16.2 5.6 0.0021 16.1 3.9 1.0 1 0 0 1 1 1 1 CDC45-like protein TRAM_LAG1_CLN8 PF03798.11 ETO21364.1 - 0.027 14.0 1.1 0.041 13.4 0.8 1.3 1 0 0 1 1 1 0 TLC domain DUF3989 PF13150.1 ETO21364.1 - 0.052 12.9 0.8 0.16 11.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) DUF1510 PF07423.6 ETO21364.1 - 0.16 11.3 12.0 0.23 10.8 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) YqfQ PF14181.1 ETO21364.1 - 0.42 10.6 5.4 0.56 10.2 3.7 1.2 1 0 0 1 1 1 0 YqfQ-like protein Tim54 PF11711.3 ETO21364.1 - 1 7.8 5.3 1.3 7.5 3.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Nop14 PF04147.7 ETO21364.1 - 2.2 6.1 16.7 2.5 5.9 11.6 1.0 1 0 0 1 1 1 0 Nop14-like family TEX19 PF15553.1 ETO21364.1 - 5.2 6.9 6.2 7.9 6.3 4.0 1.5 2 0 0 2 2 2 0 Testis-expressed protein 19 DUF2457 PF10446.4 ETO21364.1 - 5.7 5.5 20.2 7.5 5.1 14.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FAM178 PF14816.1 ETO21365.1 - 0.15 10.6 2.9 0.088 11.5 0.9 1.4 1 1 0 1 1 1 0 Family of unknown function, FAM178 WD40 PF00400.27 ETO21366.1 - 5.2e-06 26.1 0.1 0.082 12.8 0.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat PAT1 PF09770.4 ETO21368.1 - 1 7.5 20.9 1 7.4 14.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Beach PF02138.13 ETO21370.1 - 7.3e-27 94.4 0.1 1e-26 93.9 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 ETO21370.1 - 1.1e-07 31.4 0.3 1e-05 25.1 0.0 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat Nop14 PF04147.7 ETO21371.1 - 0.26 9.1 11.9 0.34 8.7 8.3 1.1 1 0 0 1 1 1 0 Nop14-like family Astro_capsid PF03115.9 ETO21371.1 - 0.36 9.0 3.7 0.48 8.6 2.6 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor CDC45 PF02724.9 ETO21371.1 - 0.77 7.7 7.9 0.98 7.3 5.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2076 PF09849.4 ETO21371.1 - 0.89 9.5 14.9 1.5 8.8 10.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) CDC27 PF09507.5 ETO21371.1 - 1.2 8.2 12.1 1.7 7.7 8.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PBP1_TM PF14812.1 ETO21371.1 - 1.5 9.1 15.8 3.4 8.0 10.9 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RRN3 PF05327.6 ETO21371.1 - 9.3 4.2 7.7 13 3.7 5.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Chal_sti_synt_N PF00195.14 ETO21372.1 - 4.5e-22 78.4 0.0 6.6e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain FAE1_CUT1_RppA PF08392.7 ETO21372.1 - 1.3e-05 24.3 0.0 2.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein Chal_sti_synt_C PF02797.10 ETO21372.1 - 0.0045 16.9 0.0 0.0099 15.8 0.0 1.5 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III PF08545.5 ETO21372.1 - 0.032 13.9 0.0 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III fn3 PF00041.16 ETO21374.1 - 0.0018 18.3 0.0 0.0068 16.5 0.0 2.0 3 0 0 3 3 3 1 Fibronectin type III domain Sld5 PF05916.6 ETO21375.1 - 0.039 14.2 2.6 0.068 13.4 1.4 2.0 1 1 0 1 1 1 0 GINS complex protein DUF745 PF05335.8 ETO21375.1 - 2.1 7.8 6.9 0.13 11.7 0.2 2.3 4 0 0 4 4 4 0 Protein of unknown function (DUF745) DUF1351 PF07083.6 ETO21376.1 - 0.0022 17.6 4.0 0.0036 16.9 2.8 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1351) bZIP_1 PF00170.16 ETO21376.1 - 0.0048 16.8 4.0 0.0048 16.8 2.8 2.6 2 1 1 3 3 3 1 bZIP transcription factor DUF1833 PF08875.6 ETO21376.1 - 0.013 14.6 0.6 0.023 13.8 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1833) CENP-F_leu_zip PF10473.4 ETO21376.1 - 0.047 13.5 14.8 0.028 14.2 5.8 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4085 PF13315.1 ETO21376.1 - 0.13 11.5 6.1 0.16 11.3 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) zf-HC5HC2H PF13771.1 ETO21376.1 - 0.87 9.7 4.7 11 6.1 0.5 3.0 2 1 1 3 3 3 0 PHD-like zinc-binding domain GLTP PF08718.6 ETO21376.1 - 0.93 9.5 5.3 0.48 10.4 1.8 1.8 1 1 1 2 2 2 0 Glycolipid transfer protein (GLTP) Ly49 PF08391.5 ETO21376.1 - 6.3 6.9 8.6 2.2 8.4 2.0 2.1 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region DUF2383 PF09537.5 ETO21377.1 - 0.011 15.9 0.1 0.037 14.2 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) WD40 PF00400.27 ETO21378.1 - 3.4e-158 508.5 48.8 2.1e-11 43.2 0.1 16.2 16 0 0 16 16 16 16 WD domain, G-beta repeat Nup160 PF11715.3 ETO21378.1 - 2.1e-16 59.1 22.6 0.031 12.4 0.1 12.3 1 1 7 9 9 9 8 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO21378.1 - 3.2e-12 46.4 4.7 1.3e-05 24.7 0.1 5.4 1 1 3 4 4 4 4 PQQ-like domain Cytochrom_D1 PF02239.11 ETO21378.1 - 1.7e-08 33.1 9.0 0.14 10.3 0.0 6.1 5 1 1 6 6 6 3 Cytochrome D1 heme domain DUF1652 PF07865.6 ETO21378.1 - 2.2e-06 27.1 0.1 9.7 5.8 0.0 7.9 7 2 2 9 9 9 1 Protein of unknown function (DUF1652) DUF1258 PF06869.7 ETO21378.1 - 8e-06 25.1 0.9 0.15 11.1 0.0 5.3 5 1 0 6 6 6 1 Protein of unknown function (DUF1258) Pentapeptide PF00805.17 ETO21378.1 - 1.4e-05 24.2 1.4 2.9e-05 23.1 1.0 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO21378.1 - 3.4e-05 23.5 0.1 0.00011 21.9 0.1 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 ETO21378.1 - 0.0013 18.5 1.0 0.0074 16.1 0.0 2.9 3 0 0 3 3 3 1 Pentapeptide repeats (9 copies) Mid2 PF04478.7 ETO21378.1 - 0.0063 15.9 7.0 9.1 5.6 0.0 6.7 6 2 3 9 9 9 1 Mid2 like cell wall stress sensor PD40 PF07676.7 ETO21378.1 - 0.016 14.8 22.3 4.2 7.1 0.2 8.6 10 0 0 10 10 10 0 WD40-like Beta Propeller Repeat NACHT PF05729.7 ETO21379.1 - 1.8e-10 40.7 0.0 5.7e-10 39.0 0.0 2.0 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO21379.1 - 1.2e-05 25.5 0.1 1.2e-05 25.5 0.1 3.4 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 ETO21379.1 - 0.00019 22.2 1.4 0.00069 20.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 ETO21379.1 - 0.00026 20.9 0.4 0.00088 19.1 0.3 2.0 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ETO21379.1 - 0.0015 18.6 0.0 0.0065 16.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain ATP_bind_2 PF03668.10 ETO21379.1 - 0.019 14.0 0.0 0.04 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop ATPase protein family AAA_33 PF13671.1 ETO21379.1 - 0.02 14.7 0.0 0.79 9.5 0.0 2.7 1 1 0 1 1 1 0 AAA domain PS_Dcarbxylase PF02666.10 ETO21380.1 - 3.8e-16 58.9 0.0 4.6e-16 58.7 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.1 ETO21380.1 - 0.016 14.8 0.0 2.1 8.0 0.0 2.9 3 0 0 3 3 3 0 Biotin-lipoyl like MRP-L51 PF10244.4 ETO21381.1 - 1.6 8.8 5.6 4.6 7.3 0.7 2.2 1 1 1 2 2 2 0 Mitochondrial ribosomal subunit Daxx PF03344.10 ETO21382.1 - 0.001 17.6 23.4 0.0013 17.3 16.2 1.2 1 0 0 1 1 1 1 Daxx Family DUF2457 PF10446.4 ETO21382.1 - 0.0041 15.9 25.7 0.0065 15.2 17.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Nop14 PF04147.7 ETO21382.1 - 0.067 11.1 30.4 0.081 10.8 21.1 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 ETO21382.1 - 0.1 11.8 25.4 0.15 11.3 17.6 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.5 ETO21382.1 - 0.49 9.4 21.5 0.63 9.0 14.9 1.2 1 0 0 1 1 1 0 BUD22 Vfa1 PF08432.5 ETO21382.1 - 1.2 9.1 18.3 2.3 8.1 12.7 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CKAP2_C PF15297.1 ETO21382.1 - 1.6 7.4 13.5 2.2 7.0 9.3 1.2 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus CDC45 PF02724.9 ETO21382.1 - 2.2 6.2 25.0 2.8 5.8 17.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.10 ETO21382.1 - 3.5 6.1 12.2 3.9 5.9 8.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Toxin_60 PF15607.1 ETO21383.1 - 0.037 14.0 0.1 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 Putative toxin 60 MxiH PF09392.5 ETO21383.1 - 0.063 13.8 0.1 0.09 13.3 0.0 1.2 1 0 0 1 1 1 0 Type III secretion needle MxiH like NYD-SP28_assoc PF14775.1 ETO21384.1 - 0.0044 16.6 0.7 0.0097 15.5 0.5 1.6 1 0 0 1 1 1 1 Sperm tail C-terminal domain RGS PF00615.14 ETO21384.1 - 0.035 14.2 0.5 0.064 13.3 0.4 1.5 1 0 0 1 1 1 0 Regulator of G protein signaling domain PIG-P PF08510.7 ETO21384.1 - 0.22 11.1 5.3 0.5 10.0 3.0 2.1 2 0 0 2 2 2 0 PIG-P DUF2457 PF10446.4 ETO21385.1 - 0.00021 20.1 21.4 0.00021 20.1 14.8 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) Daxx PF03344.10 ETO21385.1 - 0.00064 18.3 20.3 0.00064 18.3 14.1 1.6 2 0 0 2 2 2 1 Daxx Family UN_NPL4 PF11543.3 ETO21385.1 - 0.0018 18.5 5.1 0.0084 16.3 1.1 3.4 2 1 0 2 2 2 1 Nuclear pore localisation protein NPL4 CDC45 PF02724.9 ETO21385.1 - 0.034 12.1 16.3 0.01 13.9 9.2 1.6 2 0 0 2 2 2 0 CDC45-like protein G-alpha PF00503.15 ETO21386.1 - 6.1e-45 153.5 23.4 5.2e-22 78.0 0.6 3.0 2 1 0 2 2 2 2 G-protein alpha subunit Arf PF00025.16 ETO21386.1 - 7.3e-06 25.3 0.3 0.017 14.3 0.0 3.3 3 0 0 3 3 3 2 ADP-ribosylation factor family AAA_29 PF13555.1 ETO21386.1 - 0.0027 17.1 0.0 0.0067 15.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 ETO21386.1 - 0.0037 17.5 0.8 0.4 10.9 0.0 2.7 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.1 ETO21386.1 - 0.0091 15.9 0.0 0.035 14.1 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Menin PF05053.8 ETO21386.1 - 0.66 8.0 10.6 1.1 7.3 7.4 1.3 1 0 0 1 1 1 0 Menin NST1 PF13945.1 ETO21386.1 - 2.7 8.0 17.6 1.2e+02 2.6 12.2 2.5 2 0 0 2 2 2 0 Salt tolerance down-regulator AAA_18 PF13238.1 ETO21386.1 - 4.4 7.6 6.7 2.8 8.2 0.3 3.1 2 1 0 2 2 2 0 AAA domain MFS_1 PF07690.11 ETO21387.1 - 4.7e-07 28.8 14.8 1.2e-06 27.5 9.7 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETO21387.1 - 1.7e-05 23.5 1.2 1.7e-05 23.5 0.8 1.9 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 ETO21387.1 - 0.0057 15.0 8.7 0.0075 14.7 4.7 1.8 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_3 PF05977.8 ETO21387.1 - 0.01 14.0 0.0 0.015 13.4 0.0 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector ELO PF01151.13 ETO21388.1 - 6.8e-19 68.1 4.3 8.6e-19 67.8 3.0 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Aldolase_II PF00596.16 ETO21389.1 - 3.4e-19 69.1 0.1 5e-19 68.6 0.1 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Alpha_TIF PF02232.10 ETO21390.1 - 0.059 12.1 0.0 0.1 11.3 0.0 1.4 1 0 0 1 1 1 0 Alpha trans-inducing protein (Alpha-TIF) MFS_1 PF07690.11 ETO21391.1 - 5.7e-16 58.1 19.0 1.1e-15 57.2 5.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETO21391.1 - 8e-05 21.2 19.4 0.0025 16.3 8.1 3.0 1 1 2 3 3 3 2 MFS/sugar transport protein ATG22 PF11700.3 ETO21391.1 - 8.2e-05 21.2 3.5 8.2e-05 21.2 2.4 3.0 2 1 1 3 3 3 2 Vacuole effluxer Atg22 like Hum_adeno_E3A PF05393.6 ETO21391.1 - 0.36 10.5 2.2 0.52 10.0 0.0 2.2 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein DUF3278 PF11683.3 ETO21391.1 - 6.9 6.6 8.2 3.1 7.8 0.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3278) Zip PF02535.17 ETO21392.1 - 0.0093 15.0 0.0 0.012 14.6 0.0 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter UPF0233 PF06781.7 ETO21392.1 - 1.7 8.2 3.4 0.78 9.4 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) DUF4519 PF15012.1 ETO21392.1 - 2.3 8.1 8.1 6.6 6.7 5.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4519) DUF912 PF06024.7 ETO21392.1 - 5.1 7.1 18.2 1.2 9.2 0.2 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4448 PF14610.1 ETO21392.1 - 5.2 6.5 7.9 3.6 7.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) CobT PF06213.7 ETO21392.1 - 5.7 5.9 16.8 7.1 5.6 11.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TRAP_alpha PF03896.11 ETO21392.1 - 8.9 5.2 10.3 16 4.4 7.1 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Kinesin PF00225.18 ETO21393.1 - 3.6e-105 351.3 8.5 3.6e-105 351.3 5.9 4.2 4 2 0 4 4 4 1 Kinesin motor domain RNA_helicase PF00910.17 ETO21393.1 - 0.024 14.7 0.7 0.27 11.4 0.0 3.2 4 0 0 4 4 4 0 RNA helicase AAA_22 PF13401.1 ETO21393.1 - 1.1 9.4 5.7 1.9 8.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain Rad1 PF02144.11 ETO21394.1 - 1.7e-10 40.1 6.7 9.8e-08 31.0 1.0 2.9 2 1 0 2 2 2 2 Repair protein Rad1/Rec1/Rad17 PMSR PF01625.16 ETO21395.1 - 1e-17 64.4 2.7 1.2e-17 64.2 1.8 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DUF3909 PF13077.1 ETO21395.1 - 0.0037 17.1 1.9 0.0048 16.7 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3909) RCR PF12273.3 ETO21395.1 - 0.053 14.0 1.1 0.056 14.0 0.7 1.1 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Mvb12 PF09452.5 ETO21395.1 - 0.069 13.3 0.2 0.095 12.8 0.1 1.3 1 0 0 1 1 1 0 ESCRT-I subunit Mvb12 Arf PF00025.16 ETO21398.1 - 1.1e-10 41.0 0.0 2.2e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETO21398.1 - 0.02 14.0 0.2 0.052 12.6 0.1 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Ras PF00071.17 ETO21398.1 - 0.034 13.5 0.0 0.071 12.4 0.0 1.5 1 0 0 1 1 1 0 Ras family Miro PF08477.8 ETO21398.1 - 0.041 14.3 0.0 0.1 13.1 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Exo_endo_phos PF03372.18 ETO21399.1 - 1.1e-07 32.1 0.0 1.3e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RimK PF08443.6 ETO21400.1 - 3.4e-22 78.8 0.0 9.7e-15 54.5 0.0 2.2 2 0 0 2 2 2 2 RimK-like ATP-grasp domain GSH-S_ATP PF02955.11 ETO21400.1 - 5.1e-07 28.9 0.1 8.5e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain PBP1_TM PF14812.1 ETO21400.1 - 0.00026 21.2 2.8 0.0021 18.3 0.0 2.5 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF912 PF06024.7 ETO21400.1 - 0.00096 19.1 0.1 0.003 17.5 0.1 1.8 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) RIC3 PF15361.1 ETO21400.1 - 0.018 15.2 0.8 0.05 13.8 0.0 1.9 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 TRAM_LAG1_CLN8 PF03798.11 ETO21401.1 - 3.7e-10 39.6 22.5 4.4e-10 39.4 15.6 1.1 1 0 0 1 1 1 1 TLC domain HAP PF03866.8 ETO21401.1 - 0.012 15.4 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Hydrophobic abundant protein (HAP) DUSP PF06337.7 ETO21403.1 - 3.5e-09 36.9 0.0 3.5e-09 36.9 0.0 2.6 2 1 0 2 2 1 1 DUSP domain CDC45 PF02724.9 ETO21403.1 - 0.0019 16.3 9.6 0.0022 16.0 6.7 1.1 1 0 0 1 1 1 1 CDC45-like protein SprA-related PF12118.3 ETO21403.1 - 0.0036 16.6 10.8 0.0049 16.2 7.5 1.1 1 0 0 1 1 1 1 SprA-related family DUF3595 PF12166.3 ETO21403.1 - 0.03 13.1 0.7 0.036 12.8 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) DUF1510 PF07423.6 ETO21403.1 - 0.04 13.2 18.7 0.052 12.9 12.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Daxx PF03344.10 ETO21403.1 - 0.13 10.6 16.4 0.17 10.3 11.4 1.1 1 0 0 1 1 1 0 Daxx Family RNase_H2-Ydr279 PF09468.5 ETO21403.1 - 0.28 10.3 9.7 0.38 9.9 6.8 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) SID-1_RNA_chan PF13965.1 ETO21403.1 - 0.31 9.1 4.3 0.41 8.7 3.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4637 PF15470.1 ETO21403.1 - 1.3 8.6 7.7 1.9 8.1 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) RRN3 PF05327.6 ETO21403.1 - 1.3 7.0 11.2 1.6 6.7 7.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sec62 PF03839.11 ETO21403.1 - 1.9 7.8 11.5 2.8 7.3 7.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 HSP70 PF00012.15 ETO21403.1 - 2.2 6.0 14.4 2.8 5.7 10.0 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF2890 PF11081.3 ETO21403.1 - 4.7 7.2 17.5 7.3 6.6 12.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DDHD PF02862.12 ETO21403.1 - 4.9 6.8 9.6 6.9 6.3 6.7 1.2 1 0 0 1 1 1 0 DDHD domain Vfa1 PF08432.5 ETO21403.1 - 5.2 7.0 19.6 7.6 6.5 13.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Ycf1 PF05758.7 ETO21403.1 - 5.4 4.6 16.5 7 4.2 11.4 1.0 1 0 0 1 1 1 0 Ycf1 Neur_chan_memb PF02932.11 ETO21403.1 - 8.6 6.1 6.0 11 5.7 4.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Macoilin PF09726.4 ETO21404.1 - 0.13 10.5 6.5 0.14 10.3 4.5 1.0 1 0 0 1 1 1 0 Transmembrane protein Peptidase_S64 PF08192.6 ETO21404.1 - 0.48 8.6 7.5 0.58 8.4 5.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 Tim54 PF11711.3 ETO21404.1 - 8.2 4.8 9.0 10 4.5 6.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 MFS_2 PF13347.1 ETO21405.1 - 2.1e-05 23.1 6.3 2.1e-05 23.1 4.4 2.1 2 1 1 3 3 3 1 MFS/sugar transport protein MFS_1 PF07690.11 ETO21405.1 - 8.7e-05 21.3 18.1 0.00016 20.4 12.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DAO PF01266.19 ETO21406.1 - 0.00021 20.2 0.0 0.00039 19.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase AAA_23 PF13476.1 ETO21407.1 - 0.014 15.7 2.4 0.02 15.2 1.7 1.3 1 0 0 1 1 1 0 AAA domain HAUS-augmin3 PF14932.1 ETO21407.1 - 0.028 13.6 16.5 0.044 12.9 11.4 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 LMBR1 PF04791.11 ETO21407.1 - 0.039 12.5 2.4 0.053 12.1 1.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein ATG16 PF08614.6 ETO21407.1 - 0.043 13.6 16.7 0.072 12.9 11.6 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Phage_GP20 PF06810.6 ETO21407.1 - 0.062 12.7 10.6 0.097 12.1 7.4 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF4093 PF13331.1 ETO21407.1 - 0.064 13.4 3.8 0.13 12.4 2.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4093) CENP-Q PF13094.1 ETO21407.1 - 0.081 12.9 15.5 0.13 12.2 10.8 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 ETO21407.1 - 0.083 12.4 9.9 0.13 11.8 6.9 1.2 1 0 0 1 1 1 0 IncA protein Macoilin PF09726.4 ETO21407.1 - 0.15 10.3 11.3 0.23 9.6 7.8 1.3 1 0 0 1 1 1 0 Transmembrane protein Uso1_p115_C PF04871.8 ETO21407.1 - 0.56 10.1 12.6 0.9 9.4 8.7 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Mnd1 PF03962.10 ETO21407.1 - 1.5 8.4 18.5 4.4 6.9 12.8 1.8 1 1 0 1 1 1 0 Mnd1 family DUF2968 PF11180.3 ETO21407.1 - 1.9 7.8 21.0 3.8 6.8 14.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Atg14 PF10186.4 ETO21407.1 - 2.2 7.1 16.6 2.9 6.7 11.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF342 PF03961.8 ETO21407.1 - 2.6 6.3 15.9 4.2 5.6 11.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF342) FUSC PF04632.7 ETO21407.1 - 3.9 5.7 5.8 4.8 5.4 4.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family OmpH PF03938.9 ETO21407.1 - 4 7.3 19.0 6.2 6.7 13.2 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2681 PF10883.3 ETO21407.1 - 7.4 6.8 18.1 0.82 9.9 6.6 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2681) ADIP PF11559.3 ETO21407.1 - 9.6 6.0 24.6 5 7.0 14.7 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Peptidase_A22B PF04258.8 ETO21409.1 - 1.6e-38 132.8 9.6 1.6e-38 132.8 6.6 1.6 1 1 1 2 2 2 1 Signal peptide peptidase SirB PF04247.7 ETO21409.1 - 0.051 13.3 0.5 0.051 13.3 0.3 2.6 4 0 0 4 4 4 0 Invasion gene expression up-regulator, SirB DUF1119 PF06550.6 ETO21409.1 - 0.75 8.8 25.0 0.1 11.7 7.2 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1119) Prothymosin PF03247.9 ETO21411.1 - 0.001 19.1 18.1 0.0014 18.7 12.6 1.2 1 0 0 1 1 1 1 Prothymosin/parathymosin family Translin PF01997.11 ETO21411.1 - 0.047 13.2 1.7 0.053 13.1 1.2 1.1 1 0 0 1 1 1 0 Translin family DUF4551 PF15087.1 ETO21411.1 - 0.93 7.7 11.2 0.97 7.7 7.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) FLO_LFY PF01698.11 ETO21411.1 - 1.4 7.6 12.7 1.5 7.5 8.8 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Dsh_C PF12316.3 ETO21411.1 - 1.5 8.8 5.4 1.8 8.6 3.7 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Vfa1 PF08432.5 ETO21411.1 - 2.8 7.9 17.9 3.4 7.6 12.4 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 ETO21411.1 - 4.4 5.2 14.9 4.4 5.2 10.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Nucleo_P87 PF07267.6 ETO21411.1 - 5.7 5.4 14.9 6 5.4 10.3 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 UPF0560 PF10577.4 ETO21411.1 - 6.2 4.9 10.6 6.8 4.8 7.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Vfa1 PF08432.5 ETO21412.1 - 0.0021 18.1 6.9 0.0021 18.1 4.8 1.6 2 0 0 2 2 2 1 AAA-ATPase Vps4-associated protein 1 FLO_LFY PF01698.11 ETO21412.1 - 0.093 11.5 8.2 0.14 11.0 5.7 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein CobT PF06213.7 ETO21412.1 - 0.31 10.1 12.4 0.38 9.8 8.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Utp14 PF04615.8 ETO21412.1 - 0.71 7.9 20.0 0.84 7.7 13.8 1.1 1 0 0 1 1 1 0 Utp14 protein SprA-related PF12118.3 ETO21412.1 - 0.77 9.0 16.4 1.1 8.5 11.4 1.2 1 0 0 1 1 1 0 SprA-related family Hid1 PF12722.2 ETO21412.1 - 1.2 6.7 23.6 1.5 6.4 16.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2201_N PF13203.1 ETO21412.1 - 1.3 8.1 6.9 1.9 7.6 4.8 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Pox_Ag35 PF03286.9 ETO21412.1 - 2.8 7.4 17.2 0.32 10.4 7.6 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein HCO3_cotransp PF00955.16 ETO21412.1 - 3.3 6.2 4.4 4.1 5.9 3.1 1.1 1 0 0 1 1 1 0 HCO3- transporter family DUF4551 PF15087.1 ETO21412.1 - 3.9 5.7 8.3 4.6 5.4 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Pkinase PF00069.20 ETO21413.1 - 1.3e-42 145.7 0.1 2.3e-42 144.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO21413.1 - 1.1e-19 70.5 0.0 1.9e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO21413.1 - 0.01 14.9 0.1 0.028 13.4 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4530 PF15039.1 ETO21414.1 - 6.7 6.6 6.5 2 8.3 1.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) BCD PF15461.1 ETO21415.1 - 0.0016 17.9 11.4 0.0016 17.9 7.9 2.0 1 1 1 2 2 2 1 Beta-carotene 15,15'-dioxygenase ATP-synt_E PF05680.7 ETO21415.1 - 0.057 13.3 0.0 0.087 12.7 0.0 1.2 1 0 0 1 1 1 0 ATP synthase E chain CENP-F_leu_zip PF10473.4 ETO21416.1 - 1.4e-05 24.9 7.8 1.4e-05 24.9 5.4 2.1 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.1 ETO21416.1 - 0.0062 15.5 0.6 0.0091 14.9 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Spc7 PF08317.6 ETO21416.1 - 0.014 14.0 9.1 0.024 13.2 6.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein AOX PF01786.12 ETO21416.1 - 0.016 14.5 0.2 0.03 13.7 0.1 1.5 1 0 0 1 1 1 0 Alternative oxidase THOC7 PF05615.8 ETO21416.1 - 0.019 15.2 13.4 2.2 8.5 8.2 3.0 1 1 1 2 2 2 0 Tho complex subunit 7 DNA_Packaging PF11053.3 ETO21416.1 - 0.02 14.5 2.9 0.18 11.3 0.4 2.2 1 1 1 2 2 2 0 Terminase DNA packaging enzyme DUF3186 PF11382.3 ETO21416.1 - 0.032 13.3 2.9 0.09 11.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3186) Reo_sigmaC PF04582.7 ETO21416.1 - 0.043 13.0 3.8 0.063 12.4 2.6 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Atg14 PF10186.4 ETO21416.1 - 0.061 12.2 12.3 0.093 11.6 8.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1136 PF06582.7 ETO21416.1 - 0.11 12.1 0.2 0.25 11.0 0.1 1.6 1 0 0 1 1 1 0 Repeat of unknown function (DUF1136) FliJ PF02050.11 ETO21416.1 - 0.17 11.9 7.7 0.48 10.4 3.1 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein DUF2746 PF10874.3 ETO21416.1 - 0.35 11.0 3.7 0.74 10.0 1.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2746) TPR_MLP1_2 PF07926.7 ETO21416.1 - 0.38 10.5 13.5 4.4 7.0 6.7 3.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.7 ETO21416.1 - 0.38 11.0 9.0 12 6.2 3.8 3.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4140 PF13600.1 ETO21416.1 - 0.64 10.5 7.7 0.89 10.0 0.8 3.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) APG6 PF04111.7 ETO21416.1 - 0.7 8.8 10.7 1.2 8.1 7.4 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Tnp_P_element PF12017.3 ETO21416.1 - 0.79 8.9 5.0 0.43 9.7 1.5 2.0 1 1 1 2 2 2 0 Transposase protein Filament PF00038.16 ETO21416.1 - 0.88 8.9 13.2 4 6.7 8.1 2.0 1 1 0 1 1 1 0 Intermediate filament protein Jnk-SapK_ap_N PF09744.4 ETO21416.1 - 0.93 9.4 7.8 3 7.8 5.2 2.1 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Snapin_Pallidin PF14712.1 ETO21416.1 - 1.2 9.4 10.8 6.2 7.2 1.9 2.4 2 0 0 2 2 2 0 Snapin/Pallidin HrpB7 PF09486.5 ETO21416.1 - 1.4 8.8 7.2 1 9.3 0.8 2.8 1 1 3 4 4 4 0 Bacterial type III secretion protein (HrpB7) Fib_alpha PF08702.5 ETO21416.1 - 2 8.5 11.9 3.6 7.7 7.2 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF2664 PF10867.3 ETO21416.1 - 2.9 8.5 8.2 4.8 7.8 1.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2664) Herpes_LAMP2 PF06126.6 ETO21416.1 - 3.7 5.8 8.6 2 6.7 0.3 2.6 2 1 0 2 2 2 0 Herpesvirus Latent membrane protein 2 TMF_DNA_bd PF12329.3 ETO21416.1 - 5 7.0 12.9 0.54 10.0 1.7 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF2968 PF11180.3 ETO21416.1 - 6.8 6.0 12.6 1 8.6 0.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2968) Ribosomal_60s PF00428.14 ETO21417.1 - 0.25 11.7 6.2 0.38 11.1 3.5 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Sporozoite_P67 PF05642.6 ETO21417.1 - 3.5 5.3 5.3 3.4 5.4 0.0 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Nuc_sug_transp PF04142.10 ETO21418.1 - 6.9e-30 103.9 8.4 2.6e-26 92.2 2.9 2.2 1 1 0 2 2 2 2 Nucleotide-sugar transporter UAA PF08449.6 ETO21418.1 - 5.3e-05 22.2 16.3 0.00021 20.3 6.7 3.3 1 1 1 2 2 2 1 UAA transporter family EamA PF00892.15 ETO21418.1 - 0.0084 16.1 0.6 0.0084 16.1 0.4 3.3 4 0 0 4 4 4 2 EamA-like transporter family EmrE PF13536.1 ETO21418.1 - 0.02 15.0 0.1 0.02 15.0 0.1 4.0 4 1 0 4 4 4 0 Multidrug resistance efflux transporter DUF4131 PF13567.1 ETO21418.1 - 0.031 13.7 0.3 0.031 13.7 0.2 3.4 2 2 0 3 3 3 0 Domain of unknown function (DUF4131) IncA PF04156.9 ETO21418.1 - 1.1 8.7 4.1 2.9 7.4 2.8 1.7 1 0 0 1 1 1 0 IncA protein TPT PF03151.11 ETO21418.1 - 1.7 8.2 24.0 0.21 11.2 1.7 4.0 3 1 1 4 4 4 0 Triose-phosphate Transporter family MFS_1 PF07690.11 ETO21418.1 - 2.3 6.8 19.1 18 3.9 13.3 2.3 1 1 0 1 1 1 0 Major Facilitator Superfamily DUF2457 PF10446.4 ETO21419.1 - 1.1e-06 27.7 8.9 1.3e-06 27.4 6.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) DUF1510 PF07423.6 ETO21419.1 - 0.00029 20.3 18.2 0.00034 20.0 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Neur_chan_memb PF02932.11 ETO21419.1 - 0.0016 18.4 14.2 0.002 18.0 9.9 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF1183 PF06682.7 ETO21419.1 - 0.0092 15.6 1.8 0.012 15.2 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) Daxx PF03344.10 ETO21419.1 - 0.01 14.3 12.9 0.012 14.1 8.9 1.1 1 0 0 1 1 1 0 Daxx Family Nop25 PF09805.4 ETO21419.1 - 0.011 15.7 24.2 0.016 15.2 16.8 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Tetraspannin PF00335.15 ETO21419.1 - 0.037 13.2 2.0 0.052 12.8 1.4 1.3 1 0 0 1 1 1 0 Tetraspanin family PEPcase PF00311.12 ETO21419.1 - 0.039 11.8 7.1 0.048 11.5 4.9 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase CDC45 PF02724.9 ETO21419.1 - 0.12 10.3 15.8 0.14 10.1 11.0 1.1 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.10 ETO21419.1 - 0.12 10.9 12.6 0.14 10.7 8.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Menin PF05053.8 ETO21419.1 - 0.14 10.2 15.9 0.16 10.1 11.0 1.0 1 0 0 1 1 1 0 Menin Anoctamin PF04547.7 ETO21419.1 - 0.15 10.6 6.0 0.21 10.2 4.1 1.3 1 0 0 1 1 1 0 Calcium-activated chloride channel Urb2 PF10441.4 ETO21419.1 - 0.19 11.2 3.9 0.29 10.7 2.7 1.3 1 0 0 1 1 1 0 Urb2/Npa2 family DUF2217 PF10265.4 ETO21419.1 - 0.34 9.6 10.8 0.4 9.4 7.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) SID-1_RNA_chan PF13965.1 ETO21419.1 - 0.4 8.7 10.7 0.48 8.5 7.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 LMBR1 PF04791.11 ETO21419.1 - 0.4 9.1 6.8 0.42 9.1 4.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DIE2_ALG10 PF04922.7 ETO21419.1 - 0.5 9.3 5.0 0.69 8.8 3.5 1.2 1 0 0 1 1 1 0 DIE2/ALG10 family DUF2413 PF10310.4 ETO21419.1 - 0.55 8.9 24.3 0.65 8.7 16.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) STT3 PF02516.9 ETO21419.1 - 0.62 8.9 5.9 0.83 8.5 4.1 1.1 1 0 0 1 1 1 0 Oligosaccharyl transferase STT3 subunit EphA2_TM PF14575.1 ETO21419.1 - 0.75 10.2 14.3 24 5.3 9.9 2.8 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4446 PF14584.1 ETO21419.1 - 0.77 9.5 7.7 1.2 8.9 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF3260 PF11658.3 ETO21419.1 - 0.93 7.5 5.0 1.3 7.1 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Hid1 PF12722.2 ETO21419.1 - 1.1 6.8 21.2 1.2 6.6 14.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NPR3 PF03666.8 ETO21419.1 - 1.1 7.6 21.9 1.4 7.3 15.2 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 7TM_GPCR_Srv PF10323.4 ETO21419.1 - 1.2 8.1 7.2 1.2 8.2 4.3 1.5 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv DUF2076 PF09849.4 ETO21419.1 - 1.7 8.6 16.5 2.2 8.2 11.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) BTV_NS2 PF04514.7 ETO21419.1 - 2.4 6.9 17.9 3 6.6 12.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Otopetrin PF03189.8 ETO21419.1 - 2.4 7.0 7.4 2.9 6.7 5.1 1.2 1 0 0 1 1 1 0 Otopetrin DUF3684 PF12449.3 ETO21419.1 - 2.6 5.5 10.6 2.9 5.3 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3684) DUF4175 PF13779.1 ETO21419.1 - 2.9 5.4 12.3 3.5 5.2 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) 7TM_GPCR_Sru PF10322.4 ETO21419.1 - 3.1 6.8 8.1 4.2 6.3 5.6 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru DUF4407 PF14362.1 ETO21419.1 - 3.3 6.5 5.8 3.9 6.3 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MIP-T3 PF10243.4 ETO21419.1 - 3.5 5.9 31.6 4.4 5.6 21.9 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SGT1 PF07093.6 ETO21419.1 - 3.8 5.7 19.1 4.8 5.4 13.3 1.1 1 0 0 1 1 1 0 SGT1 protein UPF0560 PF10577.4 ETO21419.1 - 5.2 5.2 16.4 5.8 5.0 11.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TLC PF03219.9 ETO21419.1 - 5.7 5.2 10.1 8.1 4.7 7.0 1.2 1 0 0 1 1 1 0 TLC ATP/ADP transporter DUF2611 PF11022.3 ETO21419.1 - 5.9 7.0 8.3 15 5.7 5.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2611) CPSF73-100_C PF11718.3 ETO21419.1 - 6.2 6.1 16.2 9.9 5.4 11.3 1.3 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term SOBP PF15279.1 ETO21419.1 - 9.6 6.4 17.2 12 6.1 11.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Peroxin-3 PF04882.7 ETO21420.1 - 0.0065 15.2 2.1 0.0078 14.9 1.4 1.1 1 0 0 1 1 1 1 Peroxin-3 Rad4 PF03835.10 ETO21421.1 - 0.078 12.3 0.9 0.083 12.2 0.1 1.5 2 0 0 2 2 2 0 Rad4 transglutaminase-like domain WBP-1 PF11669.3 ETO21421.1 - 5.3 7.1 5.7 13 5.9 3.9 1.7 1 0 0 1 1 1 0 WW domain-binding protein 1 WD40 PF00400.27 ETO21422.1 - 2.1e-87 284.1 17.9 3.3e-13 48.9 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO21422.1 - 3.6e-14 52.9 3.6 2.9e-08 33.6 0.1 3.9 1 1 4 5 5 5 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO21422.1 - 1.7e-10 39.6 7.9 0.00094 17.4 1.0 4.9 1 1 2 4 4 4 3 Nucleoporin Nup120/160 PD40 PF07676.7 ETO21422.1 - 1.4e-07 30.9 12.1 0.3 10.7 0.0 7.0 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO21422.1 - 6e-07 28.5 7.2 0.53 8.9 0.2 5.5 1 1 3 4 4 4 3 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO21422.1 - 4.6e-06 25.1 0.3 0.001 17.4 0.0 2.9 1 1 3 4 4 4 1 Cytochrome D1 heme domain DUF1258 PF06869.7 ETO21422.1 - 4.7e-05 22.6 7.1 0.00041 19.5 0.2 4.0 2 1 2 5 5 5 1 Protein of unknown function (DUF1258) Resistin PF06954.6 ETO21422.1 - 0.00017 21.7 0.6 18 5.6 0.0 4.9 1 1 4 5 5 5 0 Resistin Nbas_N PF15492.1 ETO21422.1 - 0.0022 17.1 2.5 5.2 6.0 0.1 4.3 1 1 4 6 6 6 1 Neuroblastoma-amplified sequence, N terminal DPPIV_N PF00930.16 ETO21422.1 - 0.0074 14.9 0.4 1.3 7.4 0.1 3.5 1 1 1 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Utp8 PF10395.4 ETO21422.1 - 0.0077 14.5 0.6 0.22 9.7 0.1 2.2 1 1 0 2 2 2 1 Utp8 family NodS PF05401.6 ETO21422.1 - 0.013 14.9 0.6 20 4.5 0.0 4.5 4 2 2 6 6 6 0 Nodulation protein S (NodS) Colicin_Ia PF11504.3 ETO21422.1 - 0.028 14.3 0.4 42 4.1 0.0 4.6 5 0 0 5 5 5 0 Colicin Ia TFIIIC_delta PF12657.2 ETO21422.1 - 0.05 13.2 2.6 0.43 10.2 0.2 2.9 1 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term Proteasome_A_N PF10584.4 ETO21422.1 - 0.21 10.9 10.8 21 4.5 0.0 5.3 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature DUF4554 PF15091.1 ETO21423.1 - 0.097 11.3 5.5 0.11 11.2 3.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) SPX PF03105.14 ETO21423.1 - 0.5 10.0 8.8 0.61 9.8 6.1 1.1 1 0 0 1 1 1 0 SPX domain Band_3_cyto PF07565.8 ETO21423.1 - 1.5 8.2 6.2 1.8 7.9 4.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain TMEM247 PF15444.1 ETO21423.1 - 9.5 5.9 11.7 6 6.6 0.5 2.0 1 1 1 2 2 2 0 Transmembrane protein 247 Acylphosphatase PF00708.13 ETO21424.1 - 1.1e-14 54.2 0.5 2.1e-14 53.3 0.3 1.5 1 1 0 1 1 1 1 Acylphosphatase DUF4377 PF14302.1 ETO21424.1 - 0.074 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4377) CDC45 PF02724.9 ETO21425.1 - 1.5e-05 23.3 1.2 1.6e-05 23.1 0.8 1.1 1 0 0 1 1 1 1 CDC45-like protein Tim54 PF11711.3 ETO21425.1 - 0.017 13.7 2.5 0.024 13.2 1.7 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Daxx PF03344.10 ETO21425.1 - 0.044 12.2 12.8 0.059 11.8 8.9 1.1 1 0 0 1 1 1 0 Daxx Family DUF4500 PF14937.1 ETO21425.1 - 0.11 12.2 0.0 0.35 10.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) DUF1673 PF07895.6 ETO21425.1 - 0.12 11.9 3.0 0.13 11.7 1.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) DUF1510 PF07423.6 ETO21425.1 - 0.15 11.3 17.4 0.29 10.4 11.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) RNA_pol_3_Rpc31 PF11705.3 ETO21425.1 - 0.46 10.3 16.8 0.075 12.9 9.0 1.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 AIF_C PF14721.1 ETO21425.1 - 0.49 10.6 8.8 0.95 9.7 6.1 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term RR_TM4-6 PF06459.7 ETO21425.1 - 0.52 10.1 11.9 1 9.1 6.1 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Sec62 PF03839.11 ETO21425.1 - 1 8.7 9.7 0.25 10.7 4.3 1.7 2 0 0 2 2 2 0 Translocation protein Sec62 DDHD PF02862.12 ETO21425.1 - 3.2 7.4 10.3 5.2 6.7 7.1 1.2 1 0 0 1 1 1 0 DDHD domain Rota_VP2 PF05087.7 ETO21425.1 - 8.5 4.1 9.7 11 3.8 6.7 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein RskA PF10099.4 ETO21428.1 - 0.15 11.7 5.5 0.03 14.0 0.9 1.8 2 0 0 2 2 2 0 Anti-sigma-K factor rskA SET PF00856.23 ETO21431.1 - 2.3e-13 50.7 0.1 4.5e-12 46.5 0.0 2.6 2 1 0 2 2 2 1 SET domain DUF4090 PF13319.1 ETO21431.1 - 0.081 12.8 0.1 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4090) IPK PF03770.11 ETO21432.1 - 7.3e-37 126.9 2.2 2e-36 125.5 1.5 1.7 1 1 0 1 1 1 1 Inositol polyphosphate kinase CDC45 PF02724.9 ETO21432.1 - 3 5.7 18.0 4.5 5.1 12.5 1.3 1 0 0 1 1 1 0 CDC45-like protein GGDEF PF00990.16 ETO21433.1 - 0.013 15.0 0.1 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 GGDEF domain NRDE-2 PF08424.5 ETO21439.1 - 1.8 7.3 12.8 4.1 6.1 8.9 1.5 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Strabismus PF06638.6 ETO21439.1 - 4.7 5.4 7.8 1.1 7.4 3.2 1.5 2 0 0 2 2 2 0 Strabismus protein Herpes_LMP1 PF05297.6 ETO21439.1 - 5.4 5.8 17.3 11 4.8 12.0 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Chromo PF00385.19 ETO21440.1 - 1.8 8.2 6.3 14 5.4 4.4 2.3 1 1 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain USP7_ICP0_bdg PF12436.3 ETO21441.1 - 7.7e-24 84.2 0.5 9.7e-24 83.9 0.3 1.1 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 Ion_trans PF00520.26 ETO21443.1 - 3.4e-08 32.9 4.5 3.4e-08 32.9 3.1 1.6 2 0 0 2 2 2 1 Ion transport protein Ion_trans_N PF08412.5 ETO21443.1 - 7e-08 31.6 0.8 7e-08 31.6 0.5 1.8 1 1 1 2 2 2 1 Ion transport protein N-terminal DUF2730 PF10805.3 ETO21443.1 - 0.018 14.7 1.1 0.041 13.6 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Ribonuc_L-PSP PF01042.16 ETO21446.1 - 1.1e-05 25.1 0.2 6.3e-05 22.7 0.0 2.2 3 0 0 3 3 2 1 Endoribonuclease L-PSP DUF2457 PF10446.4 ETO21446.1 - 0.00094 18.0 9.3 0.0013 17.5 6.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) ARD PF03079.9 ETO21446.1 - 0.0024 17.8 1.5 0.0074 16.2 0.0 2.2 2 0 0 2 2 2 1 ARD/ARD' family Cwf_Cwc_15 PF04889.7 ETO21446.1 - 0.0097 15.6 7.3 0.013 15.2 5.1 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.8 ETO21446.1 - 0.015 14.8 3.1 0.021 14.4 2.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 ETO21446.1 - 0.017 14.6 3.7 0.027 13.9 2.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin Vfa1 PF08432.5 ETO21446.1 - 0.026 14.5 2.8 0.04 13.9 2.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NOA36 PF06524.7 ETO21446.1 - 0.046 12.9 4.7 0.067 12.4 3.3 1.3 1 0 0 1 1 1 0 NOA36 protein Bd3614_N PF14442.1 ETO21446.1 - 0.15 12.0 3.3 0.28 11.1 2.3 1.5 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal RXT2_N PF08595.6 ETO21446.1 - 0.32 10.7 6.1 0.5 10.1 4.2 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.1 ETO21446.1 - 0.34 10.5 6.6 0.58 9.8 4.6 1.4 1 0 0 1 1 1 0 FAM176 family Pox_Ag35 PF03286.9 ETO21446.1 - 0.34 10.3 10.3 0.51 9.8 7.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF908 PF06012.7 ETO21446.1 - 0.35 10.1 3.5 0.44 9.7 2.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Sporozoite_P67 PF05642.6 ETO21446.1 - 0.64 7.8 6.5 0.86 7.3 4.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CENP-B_dimeris PF09026.5 ETO21446.1 - 1.6 9.0 9.1 2.7 8.2 6.3 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC45 PF02724.9 ETO21446.1 - 3.8 5.4 8.6 5.2 4.9 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3245 PF11595.3 ETO21446.1 - 5.2 7.3 14.9 9.7 6.4 10.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3245) DUF3779 PF12621.3 ETO21448.1 - 0.011 15.6 5.6 0.083 12.7 3.9 2.4 1 1 0 1 1 1 0 Phosphate metabolism protein zf-CHCC PF10276.4 ETO21448.1 - 0.11 12.4 1.8 8.3 6.3 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger domain zf-RING_3 PF14369.1 ETO21448.1 - 0.54 10.3 3.4 0.59 10.1 0.1 2.5 2 1 0 2 2 2 0 zinc-finger Zip PF02535.17 ETO21448.1 - 4.1 6.3 12.3 7.6 5.4 8.5 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Pkinase PF00069.20 ETO21449.1 - 3.2e-27 95.3 0.1 4.9e-27 94.7 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO21449.1 - 1.7e-14 53.5 0.0 3.6e-14 52.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO21449.1 - 3.5e-05 22.9 0.1 0.0011 17.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like BTB PF00651.26 ETO21453.1 - 6.6e-10 38.9 0.9 0.00015 21.7 0.1 2.6 2 0 0 2 2 2 2 BTB/POZ domain NAD_binding_8 PF13450.1 ETO21454.1 - 4.4e-08 33.0 0.0 1.4e-07 31.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETO21454.1 - 5e-06 26.5 0.9 1.4e-05 25.0 0.6 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETO21454.1 - 5.7e-06 25.4 0.1 8.6e-06 24.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 ETO21454.1 - 5.6e-05 21.7 0.2 8.7e-05 21.1 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 ETO21454.1 - 0.00029 20.0 0.1 0.00042 19.5 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETO21454.1 - 0.00037 20.8 0.0 0.0034 17.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 ETO21454.1 - 0.00067 18.8 0.1 0.00095 18.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 ETO21454.1 - 0.001 18.0 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 ETO21454.1 - 0.0024 17.0 0.0 0.005 15.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 ETO21454.1 - 0.0055 15.6 0.3 0.027 13.3 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 ETO21454.1 - 0.014 14.3 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 ETO21454.1 - 0.039 14.0 0.0 0.087 12.8 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 ETO21455.1 - 3.4e-05 23.1 0.1 5e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 ETO21455.1 - 5e-05 22.3 0.0 0.004 16.0 0.0 2.7 2 1 1 3 3 3 1 FAD binding domain DAO PF01266.19 ETO21455.1 - 0.00023 20.2 0.0 0.00036 19.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 ETO21455.1 - 0.00068 18.8 0.0 0.13 11.3 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase TGT PF01702.13 ETO21456.1 - 4.7e-35 120.9 2.6 4.8e-27 94.7 0.0 2.7 2 1 0 2 2 2 2 Queuine tRNA-ribosyltransferase PolyA_pol_arg_C PF12626.2 ETO21456.1 - 0.039 13.5 0.3 0.076 12.6 0.2 1.4 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus NIF PF03031.13 ETO21460.1 - 5.7e-54 182.0 0.3 5.7e-54 182.0 0.2 1.6 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase TM1586_NiRdase PF14512.1 ETO21460.1 - 0.041 13.0 0.0 0.072 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative TM nitroreductase FERM_C PF09380.5 ETO21460.1 - 0.08 13.1 0.3 0.25 11.5 0.0 1.9 2 0 0 2 2 2 0 FERM C-terminal PH-like domain DUF3439 PF11921.3 ETO21461.1 - 0.66 9.7 8.3 1.4 8.7 5.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 ETO21461.1 - 5.2 6.8 15.4 11 5.7 10.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Macoilin PF09726.4 ETO21461.1 - 5.3 5.1 16.8 7.7 4.6 11.6 1.2 1 0 0 1 1 1 0 Transmembrane protein 7tm_1 PF00001.16 ETO21462.1 - 0.031 13.4 2.0 0.029 13.4 0.5 1.6 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) ODV-E18 PF10717.4 ETO21462.1 - 0.041 13.3 0.5 0.065 12.6 0.3 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 RSN1_TM PF13967.1 ETO21462.1 - 0.06 12.8 0.3 0.1 12.1 0.2 1.3 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport DUF3357 PF11837.3 ETO21462.1 - 0.072 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) EphA2_TM PF14575.1 ETO21462.1 - 0.084 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ATP-synt_8 PF00895.15 ETO21462.1 - 0.17 12.0 4.4 0.47 10.6 3.0 1.8 1 0 0 1 1 1 0 ATP synthase protein 8 Ndc1_Nup PF09531.5 ETO21463.1 - 0.0046 15.4 5.7 0.0051 15.3 3.9 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Neur_chan_memb PF02932.11 ETO21463.1 - 0.32 10.8 6.8 0.37 10.6 4.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Aldedh PF00171.17 ETO21464.1 - 2e-34 118.7 0.1 2.5e-34 118.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 ETO21464.1 - 0.012 14.3 0.0 0.015 14.0 0.0 1.1 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) RRM_5 PF13893.1 ETO21465.1 - 4e-05 23.3 0.0 9.6e-05 22.1 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO21465.1 - 0.0015 18.1 0.0 0.0041 16.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 ETO21466.1 - 4.5e-30 102.4 28.6 8.1e-12 44.5 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Coatamer_beta_C PF07718.7 ETO21466.1 - 0.063 12.9 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 Coatomer beta C-terminal region Spc24 PF08286.6 ETO21469.1 - 0.0076 15.9 7.5 0.0076 15.9 5.2 8.4 3 3 4 7 7 7 2 Spc24 subunit of Ndc80 TPR_20 PF14561.1 ETO21470.1 - 0.06 13.4 2.7 0.37 10.9 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_hydro_20b PF02838.10 ETO21470.1 - 0.092 13.2 1.7 0.1 13.1 0.2 1.7 1 1 1 2 2 2 0 Glycosyl hydrolase family 20, domain 2 Cupredoxin_1 PF13473.1 ETO21470.1 - 0.63 9.9 6.4 1.4 8.8 4.4 1.8 1 1 0 1 1 1 0 Cupredoxin-like domain Peptidase_M10 PF00413.19 ETO21470.1 - 0.69 9.6 7.2 1.7 8.3 5.0 1.7 1 1 0 1 1 1 0 Matrixin HlyD PF00529.15 ETO21470.1 - 2.4 7.3 10.9 3 7.0 7.6 1.1 1 0 0 1 1 1 0 HlyD family secretion protein DUF4407 PF14362.1 ETO21470.1 - 3 6.7 14.4 3.7 6.4 10.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.3 ETO21470.1 - 4 7.3 30.5 1.1 9.1 7.0 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1795 PF08786.6 ETO21470.1 - 4.5 7.1 15.5 0.59 9.9 1.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1795) APG6 PF04111.7 ETO21470.1 - 6.3 5.7 34.4 1.9 7.4 10.5 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF4140 PF13600.1 ETO21470.1 - 8.6 6.8 12.3 3.7 8.0 2.0 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Pkinase PF00069.20 ETO21471.1 - 2.5e-18 66.1 5.2 2.5e-13 49.7 3.5 3.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO21471.1 - 1e-10 41.1 1.4 1.3e-09 37.5 0.6 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 ETO21471.1 - 3.5e-05 22.9 0.7 5.8e-05 22.2 0.1 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 ETO21471.1 - 0.00021 20.6 0.2 0.00094 18.5 0.0 2.0 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Pro-kuma_activ PF09286.6 ETO21471.1 - 0.012 15.6 0.1 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 Pro-kumamolisin, activation domain APH PF01636.18 ETO21471.1 - 0.02 14.6 0.3 0.039 13.6 0.2 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 ETO21471.1 - 0.029 13.3 0.0 0.049 12.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like EF-hand_1 PF00036.27 ETO21472.1 - 6.5e-06 25.0 0.3 0.0013 17.9 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 ETO21472.1 - 1.5e-05 25.0 0.1 5.9e-05 23.1 0.1 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 ETO21472.1 - 8.2e-05 22.1 0.4 0.00068 19.2 0.3 2.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO21472.1 - 0.0041 16.8 0.1 0.19 11.7 0.1 3.1 2 0 0 2 2 2 1 EF-hand domain Myosin_tail_1 PF01576.14 ETO21472.1 - 0.021 12.6 31.9 0.049 11.3 21.0 1.9 1 1 1 2 2 2 0 Myosin tail EF-hand_5 PF13202.1 ETO21472.1 - 0.023 14.0 0.8 0.051 12.9 0.0 2.0 2 0 0 2 2 1 0 EF hand Filament PF00038.16 ETO21472.1 - 0.16 11.3 30.8 0.2 11.1 12.4 2.5 1 1 1 2 2 2 0 Intermediate filament protein ADIP PF11559.3 ETO21472.1 - 0.18 11.6 38.5 0.059 13.2 10.5 2.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding T2SF PF00482.18 ETO21472.1 - 0.2 11.5 1.7 0.45 10.4 0.1 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F ATP-synt_8 PF00895.15 ETO21472.1 - 0.27 11.4 1.3 1.1 9.5 0.9 2.0 1 0 0 1 1 1 0 ATP synthase protein 8 GAS PF13851.1 ETO21472.1 - 0.29 10.3 34.1 0.39 9.8 12.0 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF724 PF05266.9 ETO21472.1 - 0.4 10.2 24.8 2.7 7.5 8.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) CENP-F_leu_zip PF10473.4 ETO21472.1 - 0.41 10.5 36.8 3.1 7.6 8.0 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NEP PF10167.4 ETO21472.1 - 0.5 10.0 11.8 1.1 8.9 3.7 3.3 2 1 0 3 3 3 0 Uncharacterised conserved protein CCDC155 PF14662.1 ETO21472.1 - 0.91 9.0 39.1 0.14 11.7 12.5 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Golgin_A5 PF09787.4 ETO21472.1 - 0.96 7.8 31.0 1.8 7.0 21.5 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF2968 PF11180.3 ETO21472.1 - 1.2 8.4 33.8 1.2 8.4 8.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) APG6 PF04111.7 ETO21472.1 - 2.6 7.0 36.0 2.4 7.1 11.6 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 BLOC1_2 PF10046.4 ETO21472.1 - 3.1 7.9 21.4 20 5.4 0.6 3.6 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Transposase_22 PF02994.9 ETO21472.1 - 5.8 5.2 25.3 17 3.7 16.7 2.0 1 1 1 2 2 2 0 L1 transposable element DUF972 PF06156.8 ETO21472.1 - 7.8 6.8 30.6 3.9 7.8 7.2 3.8 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Atg14 PF10186.4 ETO21472.1 - 8.1 5.2 36.1 2.3 7.0 15.3 2.3 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4201 PF13870.1 ETO21472.1 - 8.3 5.8 42.8 0.15 11.5 4.3 4.1 2 1 0 3 3 3 0 Domain of unknown function (DUF4201) DMAP_binding PF06464.6 ETO21473.1 - 2.3 8.8 11.2 13 6.4 7.8 2.2 1 1 0 1 1 1 0 DMAP1-binding Domain PNPase PF03726.9 ETO21473.1 - 5 7.4 7.6 1.1 9.6 0.2 2.6 2 1 1 3 3 3 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain WD40 PF00400.27 ETO21474.1 - 6e-08 32.2 0.0 2.9e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 WD domain, G-beta repeat Synaptobrevin PF00957.16 ETO21475.1 - 0.17 11.5 0.1 0.17 11.5 0.0 2.2 2 0 0 2 2 2 0 Synaptobrevin TerB-N PF13208.1 ETO21475.1 - 1.1 8.6 3.1 3.5 7.0 1.7 2.0 2 0 0 2 2 2 0 TerB-N Zip PF02535.17 ETO21477.1 - 0.0052 15.8 4.4 0.24 10.3 0.1 2.5 2 0 0 2 2 2 2 ZIP Zinc transporter DUF1270 PF06900.6 ETO21477.1 - 0.081 13.0 1.1 0.24 11.5 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1270) DUF3671 PF12420.3 ETO21477.1 - 2 8.4 6.7 0.29 11.1 1.1 2.1 2 1 0 2 2 2 0 Protein of unknown function CobT PF06213.7 ETO21477.1 - 6.5 5.7 19.1 9.6 5.2 13.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT G5 PF07501.7 ETO21478.1 - 0.075 12.9 1.5 0.16 11.9 1.0 1.5 1 0 0 1 1 1 0 G5 domain Apolipoprotein PF01442.13 ETO21479.1 - 0.0076 15.7 17.4 0.024 14.1 9.3 2.2 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain bZIP_1 PF00170.16 ETO21479.1 - 0.025 14.5 3.5 0.025 14.5 2.4 4.7 3 2 1 5 5 5 0 bZIP transcription factor WD40_alt PF14077.1 ETO21479.1 - 0.026 14.1 5.6 0.99 9.0 0.3 3.0 2 1 1 3 3 3 0 Alternative WD40 repeat motif DUF883 PF05957.8 ETO21479.1 - 0.069 13.5 6.6 0.11 12.9 2.5 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) PilX PF13681.1 ETO21479.1 - 0.072 13.5 4.2 0.18 12.3 2.9 1.7 1 0 0 1 1 1 0 Type IV pilus assembly protein PilX C-term DUF4279 PF14106.1 ETO21479.1 - 0.13 12.1 1.7 0.37 10.6 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) DUF1515 PF07439.6 ETO21479.1 - 0.27 11.0 8.7 0.51 10.1 1.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) Hemerythrin PF01814.18 ETO21479.1 - 0.31 11.1 5.7 0.33 11.1 0.7 2.5 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain Reo_sigmaC PF04582.7 ETO21479.1 - 0.33 10.0 3.9 0.44 9.6 1.5 1.9 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF4248 PF14053.1 ETO21479.1 - 0.34 10.5 2.3 0.69 9.5 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) PKK PF12474.3 ETO21479.1 - 0.39 10.4 28.8 0.18 11.5 16.8 2.4 2 0 0 2 2 2 0 Polo kinase kinase DivIC PF04977.10 ETO21479.1 - 1 8.8 19.5 0.69 9.4 4.0 3.5 2 1 0 3 3 3 0 Septum formation initiator Syntaxin-6_N PF09177.6 ETO21479.1 - 3.3 8.1 17.5 11 6.4 4.4 3.4 2 1 1 3 3 3 0 Syntaxin 6, N-terminal FolB PF02152.13 ETO21480.1 - 1.4e-22 79.9 0.2 2.1e-22 79.3 0.1 1.2 1 0 0 1 1 1 1 Dihydroneopterin aldolase Uricase PF01014.13 ETO21480.1 - 0.018 15.1 0.1 0.028 14.5 0.1 1.2 1 0 0 1 1 1 0 Uricase LysM PF01476.15 ETO21481.1 - 0.004 17.0 0.0 0.0077 16.1 0.0 1.4 1 0 0 1 1 1 1 LysM domain HTH_Tnp_1 PF01527.15 ETO21481.1 - 0.092 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Transposase ENTH PF01417.15 ETO21482.1 - 1.5e-24 86.2 0.1 3.4e-24 85.0 0.1 1.6 1 0 0 1 1 1 1 ENTH domain FLO_LFY PF01698.11 ETO21482.1 - 0.0011 17.8 7.4 0.0021 16.9 5.2 1.4 1 0 0 1 1 1 1 Floricaula / Leafy protein DUF1077 PF06417.7 ETO21482.1 - 0.024 13.9 0.9 0.14 11.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1077) ANTH PF07651.11 ETO21482.1 - 0.028 13.1 0.0 0.028 13.1 0.0 2.0 2 0 0 2 2 2 0 ANTH domain Sec62 PF03839.11 ETO21482.1 - 1.4 8.2 11.7 3.9 6.8 8.1 1.8 1 0 0 1 1 1 0 Translocation protein Sec62 MIP-T3 PF10243.4 ETO21483.1 - 0.00013 20.6 25.4 0.00021 19.9 17.6 1.4 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF2457 PF10446.4 ETO21483.1 - 0.0012 17.6 30.7 0.0024 16.6 21.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) CDC45 PF02724.9 ETO21483.1 - 0.0094 14.0 24.2 0.015 13.3 16.8 1.4 1 0 0 1 1 1 1 CDC45-like protein CENP-T PF15511.1 ETO21483.1 - 0.045 12.9 14.6 0.07 12.3 10.1 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Daxx PF03344.10 ETO21483.1 - 0.31 9.4 28.0 0.45 8.9 19.4 1.2 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 ETO21483.1 - 0.34 10.2 35.5 0.95 8.7 24.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Mem_trans PF03547.13 ETO21483.1 - 0.67 8.1 3.8 0.85 7.8 2.6 1.2 1 0 0 1 1 1 0 Membrane transport protein Zip PF02535.17 ETO21483.1 - 1.3 7.9 7.7 2.4 7.0 5.3 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.11 ETO21483.1 - 2.1 8.1 9.6 1.8 8.4 5.2 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CobT PF06213.7 ETO21483.1 - 4.3 6.3 27.7 8.4 5.4 19.2 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT LMBR1 PF04791.11 ETO21483.1 - 6.1 5.3 8.5 8.4 4.8 5.9 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF684 PF05075.9 ETO21484.1 - 0.015 13.9 0.2 0.021 13.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF684) Ras PF00071.17 ETO21485.1 - 1.7e-27 95.7 0.2 2e-27 95.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO21485.1 - 7.4e-06 26.4 0.1 1.9e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein SMC_N PF02463.14 ETO21486.1 - 4.9e-29 101.1 12.4 4.3e-23 81.7 7.1 3.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 ETO21486.1 - 5.1e-08 33.4 22.5 1.8e-06 28.4 15.6 2.3 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.1 ETO21486.1 - 1.4e-07 31.7 4.9 7.9e-07 29.3 3.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 ETO21486.1 - 1.5e-05 24.4 0.0 4.1e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 ETO21486.1 - 0.00043 20.6 0.0 0.00043 20.6 0.0 2.2 2 1 0 2 2 2 1 ABC transporter AAA_16 PF13191.1 ETO21486.1 - 0.029 14.3 0.3 0.28 11.1 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 ETO21486.1 - 0.098 11.8 1.6 0.47 9.6 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function, DUF258 Syntaxin PF00804.20 ETO21486.1 - 0.67 10.1 10.3 3.2 7.9 6.3 2.4 2 0 0 2 2 2 0 Syntaxin SMC_N PF02463.14 ETO21487.1 - 4.7e-23 81.5 47.2 1.3e-22 80.1 32.6 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 ETO21487.1 - 3.5e-19 68.9 0.6 2.4e-17 63.0 0.0 3.0 2 1 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 ETO21487.1 - 2.6e-05 24.3 0.2 2.6e-05 24.3 0.1 3.3 3 1 0 3 3 3 1 AAA domain DASH_Dam1 PF08653.5 ETO21487.1 - 0.71 9.6 4.5 2.9 7.7 0.0 4.1 4 0 0 4 4 4 0 DASH complex subunit Dam1 Reo_sigmaC PF04582.7 ETO21487.1 - 1.3 8.1 15.7 0.2 10.8 4.6 3.4 3 1 0 4 4 4 0 Reovirus sigma C capsid protein DUF4225 PF13988.1 ETO21488.1 - 0.1 12.0 1.7 0.23 10.9 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) ABC_transp_aux PF09822.4 ETO21488.1 - 0.16 11.3 5.3 0.069 12.6 1.4 1.8 2 0 0 2 2 2 0 ABC-type uncharacterized transport system Citrate_synt PF00285.16 ETO21488.1 - 0.62 8.7 6.4 0.089 11.5 1.6 1.6 2 0 0 2 2 2 0 Citrate synthase TMEM192 PF14802.1 ETO21488.1 - 1 8.1 8.6 1.5 7.6 2.1 2.2 2 0 0 2 2 2 0 TMEM192 family DltD_M PF04918.7 ETO21488.1 - 2.9 8.0 15.2 0.36 10.9 6.3 2.3 2 1 0 2 2 2 0 DltD central region DUF2730 PF10805.3 ETO21488.1 - 3 7.6 12.4 0.12 12.0 1.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) ADIP PF11559.3 ETO21488.1 - 3.4 7.5 30.3 0.21 11.4 12.1 3.0 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 ETO21488.1 - 3.7 7.0 37.5 0.012 15.2 13.3 2.8 1 1 0 2 2 2 0 IncA protein bZIP_1 PF00170.16 ETO21488.1 - 5 7.1 20.6 0.2 11.6 5.5 3.9 2 1 2 4 4 4 0 bZIP transcription factor DUF4295 PF14128.1 ETO21489.1 - 0.036 13.6 0.4 0.1 12.2 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4295) DUF3373 PF11853.3 ETO21489.1 - 0.1 11.1 4.3 0.031 12.7 1.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3373) DUF1514 PF07438.6 ETO21489.1 - 0.2 11.5 1.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1514) DUF3140 PF11338.3 ETO21489.1 - 0.21 11.6 2.6 9.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3140) DJ-1_PfpI PF01965.19 ETO21490.1 - 1.8e-12 46.9 0.1 2.9e-12 46.2 0.1 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family Ank_2 PF12796.2 ETO21493.1 - 0.00061 20.0 0.0 0.61 10.4 0.0 2.8 2 2 0 2 2 2 2 Ankyrin repeats (3 copies) DED PF01335.16 ETO21493.1 - 0.032 14.3 0.1 14 5.8 0.0 2.8 2 0 0 2 2 2 0 Death effector domain Chrome_Resist PF09828.4 ETO21493.1 - 0.041 14.0 0.0 0.099 12.8 0.0 1.7 2 0 0 2 2 2 0 Chromate resistance exported protein Actin PF00022.14 ETO21494.1 - 1e-153 511.4 0.0 1.2e-153 511.2 0.0 1.0 1 0 0 1 1 1 1 Actin Cache_1 PF02743.13 ETO21494.1 - 0.013 15.0 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 Cache domain ESSS PF10183.4 ETO21494.1 - 0.075 13.4 0.0 0.33 11.3 0.0 2.0 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) EXS PF03124.9 ETO21495.1 - 7.3e-08 31.8 0.3 9e-08 31.5 0.2 1.1 1 0 0 1 1 1 1 EXS family Archaeal_AmoA PF12942.2 ETO21495.1 - 0.09 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Archaeal ammonia monooxygenase subunit A (AmoA) EFG_IV PF03764.13 ETO21496.1 - 4.3e-26 90.8 0.0 7.7e-26 90.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 ETO21496.1 - 8.5e-21 73.6 0.0 1.7e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 ETO21496.1 - 6.4e-13 48.6 0.1 2.8e-12 46.5 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 ETO21496.1 - 6.6e-13 48.3 0.0 1.3e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU PF00009.22 ETO21497.1 - 2.8e-59 199.7 0.0 3.1e-59 199.5 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 ETO21497.1 - 0.00031 20.6 0.0 0.00056 19.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.13 ETO21497.1 - 0.021 13.8 0.1 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Septin MMPL PF03176.10 ETO21499.1 - 1.3e-21 76.6 0.3 1.9e-21 76.1 0.2 1.2 1 0 0 1 1 1 1 MMPL family Tmemb_9 PF05434.6 ETO21499.1 - 0.15 11.7 0.1 0.71 9.6 0.2 1.9 2 0 0 2 2 2 0 TMEM9 MMPL PF03176.10 ETO21500.1 - 4.5e-10 38.7 0.0 6.7e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 MMPL family Zn_Tnp_IS91 PF14319.1 ETO21500.1 - 5.3 6.5 8.5 0.93 9.0 2.7 2.0 2 1 1 3 3 3 0 Transposase zinc-binding domain Kelch_1 PF01344.20 ETO21501.1 - 6.1e-15 54.4 15.1 4.6e-06 26.0 0.1 7.2 6 2 0 6 6 6 4 Kelch motif Kelch_4 PF13418.1 ETO21501.1 - 1.6e-09 37.3 2.6 0.00032 20.4 0.0 5.3 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO21501.1 - 8.5e-05 22.6 6.1 0.001 19.1 0.1 4.4 4 2 1 5 5 5 1 Galactose oxidase, central domain zf-RanBP PF00641.13 ETO21501.1 - 8.7e-05 21.5 2.2 0.00035 19.6 1.5 2.1 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Kelch_6 PF13964.1 ETO21501.1 - 0.00091 19.3 8.7 0.19 11.9 0.1 5.4 5 1 1 6 6 6 1 Kelch motif Kelch_2 PF07646.10 ETO21501.1 - 0.039 13.7 1.2 0.43 10.4 0.0 3.3 4 0 0 4 4 4 0 Kelch motif DUSP PF06337.7 ETO21502.1 - 2.3e-08 34.3 4.8 0.00057 20.2 0.0 2.9 2 1 1 3 3 3 2 DUSP domain DUF605 PF04652.11 ETO21502.1 - 0.002 17.6 6.7 0.002 17.6 4.6 1.1 1 0 0 1 1 1 1 Vta1 like Arteri_env PF01606.11 ETO21502.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Arterivirus envelope protein DUF515 PF04415.7 ETO21502.1 - 0.33 9.1 2.2 0.5 8.5 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF1765 PF08578.5 ETO21503.1 - 0.0067 16.4 0.9 0.011 15.7 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Acetyltransf_1 PF00583.19 ETO21504.1 - 3.2e-10 39.9 0.0 6.5e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETO21504.1 - 0.00014 21.9 0.3 0.00047 20.2 0.1 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 ETO21504.1 - 0.00078 19.3 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETO21504.1 - 0.0018 17.9 0.0 0.004 16.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 ETO21504.1 - 0.0026 17.5 0.0 0.0043 16.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETO21504.1 - 0.0028 17.7 0.0 0.005 16.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 ETO21504.1 - 0.0092 16.1 0.0 0.025 14.7 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain eIF3_p135 PF12807.2 ETO21505.1 - 0.012 15.5 0.6 0.026 14.4 0.3 1.5 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 PT-HINT PF07591.6 ETO21506.1 - 1.3e-09 38.0 0.2 2.2e-08 34.0 0.1 2.0 1 1 0 1 1 1 1 Pretoxin HINT domain AXH PF08517.7 ETO21506.1 - 2.1e-05 24.6 0.1 3.7e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) YajC PF02699.10 ETO21506.1 - 0.0081 15.8 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Preprotein translocase subunit TNF PF00229.13 ETO21506.1 - 0.06 12.9 0.2 0.11 12.0 0.0 1.5 2 0 0 2 2 2 0 TNF(Tumour Necrosis Factor) family Hint_2 PF13403.1 ETO21506.1 - 0.14 12.0 0.0 0.81 9.6 0.0 1.8 1 1 0 1 1 1 0 Hint domain TPR_12 PF13424.1 ETO21507.1 - 6e-47 157.4 12.8 1.6e-19 69.6 0.1 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO21507.1 - 1.9e-21 74.0 6.9 1.6e-06 27.4 0.0 5.6 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETO21507.1 - 8.1e-21 73.4 11.9 3.4e-09 36.1 0.4 3.8 1 1 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 ETO21507.1 - 1.8e-19 68.4 24.0 2.1e-05 23.9 0.8 5.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETO21507.1 - 2.1e-19 68.7 0.0 4.5e-07 29.5 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO21507.1 - 2.7e-16 58.1 19.9 0.00044 19.9 0.2 5.6 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.1 ETO21507.1 - 4.7e-12 44.7 19.4 0.0013 18.3 0.8 5.8 5 0 0 5 5 5 5 Tetratricopeptide repeat MIT PF04212.13 ETO21507.1 - 1.2e-06 28.3 7.1 0.17 11.8 0.0 5.3 5 0 0 5 5 5 2 MIT (microtubule interacting and transport) domain TPR_14 PF13428.1 ETO21507.1 - 0.00064 20.1 0.0 9.6 7.1 0.0 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO21507.1 - 0.0016 17.6 0.0 0.62 9.3 0.0 2.7 2 0 0 2 2 2 2 SHNi-TPR TPR_6 PF13174.1 ETO21507.1 - 0.0023 18.2 3.3 8.8 7.0 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO21507.1 - 0.0086 16.7 0.0 11 6.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 ETO21507.1 - 0.0094 16.0 8.0 0.27 11.5 0.0 5.5 6 2 1 7 7 6 1 Tetratricopeptide repeat PPR PF01535.15 ETO21507.1 - 0.36 10.8 3.8 20 5.4 0.0 4.0 4 0 0 4 4 4 0 PPR repeat Enkurin PF13864.1 ETO21508.1 - 7.8e-22 77.3 13.1 1.6e-21 76.3 9.1 1.5 1 0 0 1 1 1 1 Calmodulin-binding Arylsulfotrans PF05935.6 ETO21508.1 - 0.089 11.2 3.9 1.9 6.8 0.1 2.1 1 1 1 2 2 2 0 Arylsulfotransferase (ASST) AAA_23 PF13476.1 ETO21508.1 - 0.17 12.2 14.9 0.23 11.7 10.3 1.3 1 0 0 1 1 1 0 AAA domain OSCP PF00213.13 ETO21508.1 - 0.18 11.6 6.0 0.29 11.0 4.1 1.3 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit Synaptonemal_3 PF15191.1 ETO21508.1 - 0.41 10.4 4.1 0.53 10.0 0.1 2.6 1 1 1 2 2 2 0 Synaptonemal complex central element protein 3 IncA PF04156.9 ETO21510.1 - 1.1e-05 25.0 4.6 2.1e-05 24.1 3.2 1.4 1 1 0 1 1 1 1 IncA protein NPV_P10 PF05531.7 ETO21510.1 - 6.1e-05 23.1 2.2 0.00015 21.9 1.4 1.7 1 1 0 1 1 1 1 Nucleopolyhedrovirus P10 protein TBPIP PF07106.8 ETO21510.1 - 0.00025 20.6 0.6 0.00038 20.0 0.4 1.3 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3450 PF11932.3 ETO21510.1 - 0.00066 19.0 3.0 0.0011 18.2 2.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Baculo_PEP_C PF04513.7 ETO21510.1 - 0.00072 19.3 1.1 0.0012 18.6 0.8 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus TMPIT PF07851.8 ETO21510.1 - 0.00098 18.2 1.1 0.0015 17.6 0.8 1.2 1 0 0 1 1 1 1 TMPIT-like protein TMF_TATA_bd PF12325.3 ETO21510.1 - 0.00099 18.8 3.8 0.0019 17.8 2.6 1.5 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding HAP1_N PF04849.8 ETO21510.1 - 0.0024 16.8 2.2 0.0044 16.0 1.5 1.4 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Tropomyosin_1 PF12718.2 ETO21510.1 - 0.0036 17.1 4.4 0.0073 16.1 3.1 1.5 1 0 0 1 1 1 1 Tropomyosin like PspA_IM30 PF04012.7 ETO21510.1 - 0.0062 15.9 0.7 0.01 15.2 0.5 1.3 1 0 0 1 1 1 1 PspA/IM30 family Filament PF00038.16 ETO21510.1 - 0.0064 15.9 3.1 0.01 15.3 2.2 1.3 1 0 0 1 1 1 1 Intermediate filament protein HALZ PF02183.13 ETO21510.1 - 0.0071 16.0 1.0 0.55 10.0 0.0 2.6 2 1 0 2 2 2 1 Homeobox associated leucine zipper CENP-F_leu_zip PF10473.4 ETO21510.1 - 0.0072 16.1 9.7 0.023 14.5 6.8 1.7 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.17 ETO21510.1 - 0.0094 15.9 1.2 0.0094 15.9 0.8 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain AAA_13 PF13166.1 ETO21510.1 - 0.0099 14.4 1.2 0.013 13.9 0.8 1.2 1 0 0 1 1 1 1 AAA domain ADIP PF11559.3 ETO21510.1 - 0.01 15.7 5.6 0.017 14.9 3.9 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Lipoprotein_7 PF01540.11 ETO21510.1 - 0.013 14.6 0.2 0.013 14.5 0.1 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein Reo_sigmaC PF04582.7 ETO21510.1 - 0.015 14.5 0.4 0.022 13.9 0.3 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein CCDC155 PF14662.1 ETO21510.1 - 0.024 14.2 5.5 0.038 13.5 3.8 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 APG6 PF04111.7 ETO21510.1 - 0.024 13.7 3.6 0.039 12.9 2.5 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF812 PF05667.6 ETO21510.1 - 0.027 12.9 3.7 0.039 12.4 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) WXG100 PF06013.7 ETO21510.1 - 0.033 14.1 1.3 0.64 10.0 0.9 2.2 1 1 0 1 1 1 0 Proteins of 100 residues with WXG DUF2205 PF10224.4 ETO21510.1 - 0.04 13.4 5.6 0.61 9.6 0.6 2.3 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) TPR_MLP1_2 PF07926.7 ETO21510.1 - 0.046 13.4 8.0 0.26 11.0 5.6 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein AAA_27 PF13514.1 ETO21510.1 - 0.068 10.8 1.0 0.091 10.4 0.7 1.1 1 0 0 1 1 1 0 AAA domain LUC7 PF03194.10 ETO21510.1 - 0.076 12.5 1.2 0.12 11.8 0.9 1.3 1 0 0 1 1 1 0 LUC7 N_terminus DUF2968 PF11180.3 ETO21510.1 - 0.078 12.3 0.7 0.15 11.4 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Spc7 PF08317.6 ETO21510.1 - 0.079 11.6 3.5 0.13 10.9 2.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Phage_GP20 PF06810.6 ETO21510.1 - 0.081 12.3 3.9 0.17 11.3 2.7 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF3377 PF11857.3 ETO21510.1 - 0.084 12.5 0.3 0.23 11.1 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Snapin_Pallidin PF14712.1 ETO21510.1 - 0.086 13.1 2.6 0.2 11.9 1.8 1.7 1 0 0 1 1 1 0 Snapin/Pallidin Fzo_mitofusin PF04799.8 ETO21510.1 - 0.15 11.4 3.7 0.28 10.5 2.6 1.5 1 1 0 1 1 1 0 fzo-like conserved region DUF342 PF03961.8 ETO21510.1 - 0.16 10.3 2.4 0.24 9.7 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) YscO PF07321.7 ETO21510.1 - 0.17 11.6 3.6 0.31 10.8 2.5 1.4 1 0 0 1 1 1 0 Type III secretion protein YscO Med4 PF10018.4 ETO21510.1 - 0.18 11.1 4.9 0.23 10.8 0.4 2.1 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 FlaC_arch PF05377.6 ETO21510.1 - 0.19 11.6 4.5 1.3 8.9 0.8 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.10 ETO21510.1 - 0.19 11.2 6.5 1.6 8.3 1.5 2.8 1 1 2 3 3 3 0 Septum formation initiator Laminin_II PF06009.7 ETO21510.1 - 0.21 11.3 3.9 0.94 9.2 2.3 1.6 1 1 0 1 1 1 0 Laminin Domain II ATG16 PF08614.6 ETO21510.1 - 0.25 11.1 7.2 0.089 12.6 2.9 1.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.7 ETO21510.1 - 0.28 10.9 5.0 0.57 9.9 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) OPA3 PF07047.7 ETO21510.1 - 0.31 10.7 1.8 0.61 9.8 0.3 2.1 2 1 0 2 2 2 0 Optic atrophy 3 protein (OPA3) SlyX PF04102.7 ETO21510.1 - 0.34 11.3 2.9 1.2 9.6 2.1 1.9 1 1 1 2 2 2 0 SlyX YlbD_coat PF14071.1 ETO21510.1 - 0.51 10.4 4.5 0.086 12.9 0.5 1.6 2 0 0 2 2 1 0 Putative coat protein Med28 PF11594.3 ETO21510.1 - 0.54 10.5 4.2 3.6 7.8 2.9 2.1 1 1 0 1 1 1 0 Mediator complex subunit 28 Fib_alpha PF08702.5 ETO21510.1 - 0.55 10.3 4.8 7 6.7 1.3 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF724 PF05266.9 ETO21510.1 - 0.97 9.0 7.2 0.14 11.7 2.2 1.6 2 1 0 2 2 1 0 Protein of unknown function (DUF724) DivIVA PF05103.8 ETO21510.1 - 1 9.4 7.2 1.5 8.8 0.6 2.2 1 1 1 2 2 2 0 DivIVA protein DUF641 PF04859.7 ETO21510.1 - 1.1 9.0 5.7 0.36 10.6 2.0 1.6 2 0 0 2 2 1 0 Plant protein of unknown function (DUF641) BLOC1_2 PF10046.4 ETO21510.1 - 1.3 9.1 7.9 0.12 12.5 2.3 1.7 2 0 0 2 2 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prefoldin_2 PF01920.15 ETO21510.1 - 1.3 8.7 8.8 0.38 10.5 1.6 2.4 1 1 1 2 2 2 0 Prefoldin subunit V_ATPase_I PF01496.14 ETO21510.1 - 1.4 6.6 8.5 0.059 11.2 1.4 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family zf-C4H2 PF10146.4 ETO21510.1 - 1.5 8.7 4.2 2.5 8.0 2.9 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein bZIP_1 PF00170.16 ETO21510.1 - 1.6 8.7 4.6 1.5 8.8 0.9 2.3 1 1 1 2 2 2 0 bZIP transcription factor DASH_Dam1 PF08653.5 ETO21510.1 - 3.4 7.4 5.1 23 4.8 0.5 2.8 1 1 2 3 3 3 0 DASH complex subunit Dam1 Spc24 PF08286.6 ETO21510.1 - 4.4 7.0 9.7 2.1 8.0 4.7 2.1 2 1 0 2 2 1 0 Spc24 subunit of Ndc80 DUF972 PF06156.8 ETO21510.1 - 5.2 7.4 11.0 1.1 9.6 1.0 2.6 2 1 1 3 3 2 0 Protein of unknown function (DUF972) TMF_DNA_bd PF12329.3 ETO21510.1 - 6.5 6.6 9.4 1.9 8.3 3.0 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Claudin_2 PF13903.1 ETO21511.1 - 0.0068 16.1 1.4 0.011 15.4 1.0 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction RskA PF10099.4 ETO21512.1 - 0.026 14.2 0.0 0.028 14.1 0.0 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF458 PF04308.7 ETO21512.1 - 0.046 13.4 0.7 0.16 11.6 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF458) MotA_ExbB PF01618.11 ETO21512.1 - 0.048 13.2 5.0 0.05 13.2 2.7 1.6 1 1 1 2 2 2 0 MotA/TolQ/ExbB proton channel family Glyco_transf_41 PF13844.1 ETO21512.1 - 0.076 10.9 0.2 0.074 11.0 0.2 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 41 ADH_zinc_N_2 PF13602.1 ETO21512.1 - 0.12 13.2 0.0 0.14 13.0 0.0 1.2 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF533 PF04391.7 ETO21512.1 - 0.69 9.2 3.9 1.3 8.4 2.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF533) DUF3649 PF12365.3 ETO21512.1 - 3.3 7.3 7.0 4.9 6.7 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3649) Peptidase_M48 PF01435.13 ETO21513.1 - 4.4e-05 23.1 0.9 6.6e-05 22.5 0.6 1.3 1 1 0 1 1 1 1 Peptidase family M48 ASFV_J13L PF05568.6 ETO21513.1 - 0.02 14.4 9.0 0.031 13.8 6.3 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF2207 PF09972.4 ETO21513.1 - 0.34 9.4 6.5 0.36 9.3 4.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SUR7 PF06687.7 ETO21513.1 - 0.4 10.2 12.2 0.51 9.8 8.4 1.2 1 0 0 1 1 1 0 SUR7/PalI family EzrA PF06160.7 ETO21513.1 - 4.4 5.3 10.0 5.9 4.9 7.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA SDF PF00375.13 ETO21513.1 - 6.9 5.3 14.2 8.9 4.9 9.9 1.1 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family TPR_11 PF13414.1 ETO21515.1 - 0.00043 19.8 6.3 0.0021 17.6 0.6 2.5 1 1 1 2 2 2 2 TPR repeat TPR_17 PF13431.1 ETO21515.1 - 0.0014 18.6 0.1 0.01 15.9 0.0 2.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO21515.1 - 0.0014 19.2 0.7 0.0076 16.8 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO21515.1 - 0.84 10.2 0.1 0.84 10.2 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1443 PF07280.6 ETO21516.1 - 0.38 10.3 5.5 1.1 8.9 3.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1443) EF-hand_8 PF13833.1 ETO21517.1 - 7.3e-09 35.1 0.4 1.6e-08 34.0 0.3 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO21517.1 - 3.5e-06 25.9 0.1 0.014 14.6 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 ETO21517.1 - 0.00013 22.0 0.5 0.00067 19.7 0.2 2.1 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO21517.1 - 0.00033 20.2 0.1 0.015 15.1 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain SAM_2 PF07647.12 ETO21518.1 - 1.7e-26 91.8 8.1 6.3e-09 35.5 0.1 4.1 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO21518.1 - 8.2e-21 73.9 14.2 2.9e-09 36.9 0.1 4.0 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) Reo_sigmaC PF04582.7 ETO21518.1 - 1.1e-05 24.7 4.9 0.00021 20.5 2.5 2.5 2 1 0 2 2 2 1 Reovirus sigma C capsid protein FliJ PF02050.11 ETO21518.1 - 7.8e-05 22.7 7.4 7.8e-05 22.7 5.2 5.5 6 1 0 6 6 6 2 Flagellar FliJ protein Rootletin PF15035.1 ETO21518.1 - 0.003 17.5 29.3 0.01 15.8 6.9 4.5 4 0 0 4 4 4 2 Ciliary rootlet component, centrosome cohesion SAM_PNT PF02198.11 ETO21518.1 - 0.0092 15.7 2.6 1.9 8.2 0.1 3.5 3 0 0 3 3 3 1 Sterile alpha motif (SAM)/Pointed domain AAA_13 PF13166.1 ETO21518.1 - 1.5 7.2 38.8 0.047 12.1 16.6 3.1 3 0 0 3 3 3 0 AAA domain Filament PF00038.16 ETO21518.1 - 7.2 5.9 36.5 3.1 7.1 7.9 4.4 3 1 1 4 4 4 0 Intermediate filament protein PrmA PF06325.8 ETO21519.1 - 4e-11 42.5 0.0 6.1e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) SH3_2 PF07653.12 ETO21519.1 - 1.9e-09 36.8 0.0 5.4e-09 35.4 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 ETO21519.1 - 1.4e-08 34.1 0.2 3e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain Methyltransf_26 PF13659.1 ETO21519.1 - 3.4e-08 33.5 0.0 6.9e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETO21519.1 - 5.9e-08 32.2 0.0 8.1e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 ETO21519.1 - 2.9e-07 31.0 0.0 1.5e-06 28.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETO21519.1 - 1e-06 29.0 0.0 2.9e-06 27.6 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain SH3_1 PF00018.23 ETO21519.1 - 1.1e-06 27.9 0.1 2.1e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain Methyltransf_31 PF13847.1 ETO21519.1 - 1.3e-06 28.0 0.1 2.2e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETO21519.1 - 3.3e-05 23.6 0.0 4.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 ETO21519.1 - 0.00048 19.7 0.1 0.00074 19.1 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.10 ETO21519.1 - 0.00068 19.0 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.1 ETO21519.1 - 0.0007 19.9 0.1 0.0015 18.8 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain CMAS PF02353.15 ETO21519.1 - 0.0085 15.1 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 ETO21519.1 - 0.016 15.6 0.0 0.039 14.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.6 ETO21519.1 - 0.028 13.1 0.0 0.036 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.1 ETO21519.1 - 0.035 13.7 0.1 0.064 12.9 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 ETO21519.1 - 0.037 13.9 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase UPF0020 PF01170.13 ETO21519.1 - 0.041 13.4 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 TehB PF03848.9 ETO21519.1 - 0.043 12.9 0.0 0.065 12.3 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_24 PF13578.1 ETO21519.1 - 0.044 14.6 0.0 0.11 13.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 ETO21519.1 - 0.049 13.1 0.1 0.068 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) zf-RanBP PF00641.13 ETO21522.1 - 0.00057 18.9 5.7 0.0014 17.6 4.0 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DZR PF12773.2 ETO21522.1 - 0.023 14.5 1.6 0.056 13.2 1.1 1.6 1 0 0 1 1 1 0 Double zinc ribbon LNS2 PF08235.8 ETO21523.1 - 2e-45 154.2 0.0 3.3e-45 153.4 0.0 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 ETO21523.1 - 6.3e-11 41.9 0.0 4.2e-10 39.2 0.0 2.3 1 1 0 1 1 1 1 lipin, N-terminal conserved region PNK3P PF08645.6 ETO21523.1 - 0.0034 16.8 0.0 0.0099 15.3 0.0 1.8 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase F-box-like PF12937.2 ETO21525.1 - 1.4e-06 27.8 0.8 2.9e-06 26.9 0.6 1.5 1 0 0 1 1 1 1 F-box-like CCP_MauG PF03150.9 ETO21525.1 - 0.13 12.5 0.2 0.66 10.2 0.0 1.9 1 1 0 2 2 2 0 Di-haem cytochrome c peroxidase DHO_dh PF01180.16 ETO21526.1 - 0.048 12.6 2.4 0.057 12.3 1.6 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase RGS PF00615.14 ETO21527.1 - 0.0024 17.9 0.6 0.0081 16.2 0.0 2.1 2 1 1 3 3 3 1 Regulator of G protein signaling domain CN_hydrolase PF00795.17 ETO21528.1 - 2.7e-21 75.7 0.0 4.6e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase UCH PF00443.24 ETO21529.1 - 1e-09 37.9 2.5 1e-09 37.9 1.7 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Bac_small_YrzI PF09501.5 ETO21529.1 - 1.2 9.1 5.9 3.5 7.6 0.1 2.8 1 1 1 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) Nop25 PF09805.4 ETO21529.1 - 1.9 8.5 12.0 0.044 13.8 2.7 2.0 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Glyco_transf_10 PF00852.14 ETO21530.1 - 7.3e-38 130.0 0.1 1.1e-37 129.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) RRM_1 PF00076.17 ETO21532.1 - 1.2e-05 24.8 0.0 2.7e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO21532.1 - 0.0018 18.0 0.0 0.0067 16.2 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPX PF03105.14 ETO21532.1 - 0.004 16.9 18.3 0.059 13.1 3.8 2.2 2 0 0 2 2 2 2 SPX domain RRM_6 PF14259.1 ETO21532.1 - 0.0047 16.8 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Zip PF02535.17 ETO21532.1 - 0.027 13.4 8.3 0.09 11.7 0.0 2.3 1 1 0 2 2 2 0 ZIP Zinc transporter DUF1482 PF07358.6 ETO21532.1 - 0.16 11.5 1.1 0.33 10.5 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1482) CDC45 PF02724.9 ETO21532.1 - 0.59 8.0 13.1 0.79 7.6 3.0 2.1 2 0 0 2 2 2 0 CDC45-like protein Pox_Ag35 PF03286.9 ETO21532.1 - 0.98 8.9 22.4 1.8 8.0 3.9 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein MFMR PF07777.6 ETO21532.1 - 3.1 7.6 13.3 0.79 9.6 1.1 2.4 2 0 0 2 2 2 0 G-box binding protein MFMR Apis_Csd PF11671.3 ETO21532.1 - 3.9 7.2 34.0 6.2 6.6 11.0 2.4 2 0 0 2 2 2 0 Complementary sex determiner protein Menin PF05053.8 ETO21532.1 - 7.6 4.5 19.8 0.71 7.9 1.8 2.1 2 0 0 2 2 2 0 Menin MIF PF01187.13 ETO21533.1 - 0.084 12.9 0.1 0.23 11.5 0.0 1.7 2 0 0 2 2 2 0 Macrophage migration inhibitory factor (MIF) CTP_transf_3 PF02348.14 ETO21534.1 - 0.076 12.6 1.4 0.12 11.9 0.6 1.6 1 1 0 1 1 1 0 Cytidylyltransferase DUF2841 PF11001.3 ETO21534.1 - 0.24 11.2 3.2 7.4 6.4 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2841) 2OG-FeII_Oxy PF03171.15 ETO21536.1 - 0.0019 18.4 1.2 0.02 15.1 0.4 2.5 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Glyco_trans_1_4 PF13692.1 ETO21537.1 - 8.9e-11 42.0 0.0 4.1e-10 39.9 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 ETO21537.1 - 0.0003 20.9 0.0 0.00064 19.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 ETO21537.1 - 0.081 12.6 0.5 0.55 9.9 0.0 2.4 3 0 0 3 3 3 0 Glycosyltransferase Family 4 Ribosomal_S2 PF00318.15 ETO21538.1 - 0.46 9.6 2.6 0.2 10.8 0.1 1.6 2 0 0 2 2 2 0 Ribosomal protein S2 Cwf_Cwc_15 PF04889.7 ETO21538.1 - 1 9.0 20.4 1.6 8.3 14.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Neur_chan_memb PF02932.11 ETO21539.1 - 0.03 14.2 12.1 0.19 11.5 8.4 2.0 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF912 PF06024.7 ETO21539.1 - 0.53 10.3 0.0 0.53 10.3 0.0 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CDC45 PF02724.9 ETO21541.1 - 6e-05 21.2 9.8 7.2e-05 21.0 6.8 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.7 ETO21541.1 - 0.0062 14.5 12.0 0.0066 14.4 8.3 1.0 1 0 0 1 1 1 1 Nop14-like family DUF1510 PF07423.6 ETO21541.1 - 0.028 13.7 4.6 0.039 13.3 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SGT1 PF07093.6 ETO21541.1 - 0.036 12.4 11.5 0.042 12.2 7.9 1.1 1 0 0 1 1 1 0 SGT1 protein DUF2457 PF10446.4 ETO21541.1 - 0.11 11.1 27.9 0.14 10.8 19.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BTV_NS2 PF04514.7 ETO21541.1 - 0.18 10.6 5.5 0.24 10.2 3.8 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 RRN3 PF05327.6 ETO21541.1 - 0.25 9.4 11.3 0.32 9.0 7.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CENP-B_dimeris PF09026.5 ETO21541.1 - 0.29 11.3 16.7 0.6 10.3 11.6 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain BUD22 PF09073.5 ETO21541.1 - 0.32 10.0 10.8 0.38 9.7 7.5 1.1 1 0 0 1 1 1 0 BUD22 Nop25 PF09805.4 ETO21541.1 - 0.56 10.2 8.5 0.78 9.8 5.9 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Sigma70_ner PF04546.8 ETO21541.1 - 0.66 9.5 11.2 1.1 8.8 7.8 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF3295 PF11702.3 ETO21541.1 - 5 5.9 11.9 5.8 5.7 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) TPR_12 PF13424.1 ETO21542.1 - 2.5e-139 453.5 18.0 9.7e-29 99.1 0.1 5.9 1 1 6 7 7 7 7 Tetratricopeptide repeat TPR_11 PF13414.1 ETO21542.1 - 5e-72 237.5 41.5 1e-16 60.3 0.8 4.8 1 1 6 7 7 7 6 TPR repeat TPR_10 PF13374.1 ETO21542.1 - 8.8e-57 187.5 0.0 1.2e-09 37.7 0.0 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.1 ETO21542.1 - 7.9e-55 178.3 8.1 3.2e-08 32.7 0.0 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETO21542.1 - 7.6e-51 167.7 33.5 7.9e-11 41.0 0.8 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 ETO21542.1 - 2.4e-41 136.3 18.8 4.7e-08 32.3 0.2 7.1 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETO21542.1 - 8.5e-37 122.1 42.3 1.1e-08 34.2 1.3 6.8 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.1 ETO21542.1 - 2.7e-29 98.8 10.5 0.00014 21.7 0.0 6.9 6 2 0 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 ETO21542.1 - 6.3e-19 68.1 0.0 7.4e-06 26.4 0.0 4.9 2 1 4 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO21542.1 - 2.1e-16 58.9 0.0 0.076 13.6 0.0 6.2 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.1 ETO21542.1 - 9.6e-14 50.8 2.2 0.17 12.4 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO21542.1 - 9.4e-13 48.3 0.6 0.014 15.6 0.1 4.6 1 1 4 5 5 5 5 Tetratricopeptide repeat PPR PF01535.15 ETO21542.1 - 5.6e-12 44.7 12.1 0.062 13.3 0.1 6.1 6 0 0 6 6 6 4 PPR repeat Apc3 PF12895.2 ETO21542.1 - 1.1e-11 44.6 8.1 8.6e-06 25.7 1.6 3.1 1 1 2 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.1 ETO21542.1 - 1.2e-11 44.3 7.7 9.6e-06 24.9 2.1 3.9 1 1 0 2 2 2 2 Soluble NSF attachment protein, SNAP MIT PF04212.13 ETO21542.1 - 6.4e-10 38.7 26.0 0.0096 15.7 0.5 6.5 6 1 1 7 7 7 4 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 ETO21542.1 - 1.8e-08 34.0 25.7 0.063 13.0 0.4 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat DUF627 PF04781.7 ETO21542.1 - 1e-07 31.5 9.1 0.062 12.9 0.3 5.8 2 2 4 6 6 6 2 Protein of unknown function (DUF627) RPN7 PF10602.4 ETO21542.1 - 2.8e-06 26.8 9.8 0.47 9.8 0.4 5.0 2 1 3 5 5 5 2 26S proteasome subunit RPN7 Musclin PF11037.3 ETO21542.1 - 1.1e-05 25.0 0.0 20 4.8 0.0 5.5 6 0 0 6 6 6 0 Insulin-resistance promoting peptide in skeletal muscle Pep3_Vps18 PF05131.9 ETO21542.1 - 4e-05 23.0 0.6 9.9 5.5 0.0 5.0 5 0 0 5 5 5 0 Pep3/Vps18/deep orange family Mad3_BUB1_I PF08311.7 ETO21542.1 - 5.3e-05 22.9 2.1 5.5 6.7 0.0 4.5 5 0 0 5 5 5 0 Mad3/BUB1 homology region 1 PPR_2 PF13041.1 ETO21542.1 - 7.2e-05 22.6 5.5 2 8.4 0.0 4.8 5 0 0 5 5 5 1 PPR repeat family Ten1_2 PF15490.1 ETO21542.1 - 9.8e-05 21.9 0.0 8.9 5.9 0.0 4.8 1 1 5 6 6 6 0 Telomere-capping, CST complex subunit Sel1 PF08238.7 ETO21542.1 - 0.0003 21.3 15.4 3 8.6 0.1 6.3 7 0 0 7 7 6 1 Sel1 repeat SHNi-TPR PF10516.4 ETO21542.1 - 0.0052 15.9 0.0 17 4.7 0.0 4.9 5 0 0 5 5 5 0 SHNi-TPR DLD PF14878.1 ETO21542.1 - 0.0073 16.3 0.8 13 5.8 0.0 4.4 2 2 3 5 5 5 0 Death-like domain of SPT6 Syntaxin_2 PF14523.1 ETO21542.1 - 0.04 13.9 0.0 13 5.8 0.0 4.1 3 1 3 6 6 5 0 Syntaxin-like protein SERTA PF06031.8 ETO21542.1 - 0.048 12.9 0.5 62 3.0 0.0 4.2 5 0 0 5 5 5 0 SERTA motif Clathrin PF00637.15 ETO21542.1 - 0.08 12.5 6.7 3.1 7.3 0.3 4.2 2 2 1 3 3 3 0 Region in Clathrin and VPS DUF2225 PF09986.4 ETO21542.1 - 0.081 12.3 7.3 7.7 5.9 0.2 3.8 1 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_21 PF09976.4 ETO21542.1 - 0.11 12.4 3.1 40 4.1 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat Rab5-bind PF09311.6 ETO21542.1 - 0.13 12.1 0.0 83 3.0 0.0 3.4 1 1 2 4 4 4 0 Rabaptin-like protein FATC PF02260.15 ETO21542.1 - 2.2 7.7 5.7 57 3.2 0.0 3.6 4 0 0 4 4 3 0 FATC domain PG_binding_2 PF08823.6 ETO21542.1 - 5.3 7.2 7.3 74 3.5 0.0 4.6 3 2 3 6 6 6 0 Putative peptidoglycan binding domain CHAT PF12770.2 ETO21543.1 - 2e-13 50.1 0.6 3.9e-13 49.1 0.2 1.6 2 0 0 2 2 2 1 CHAT domain Secretin_N_2 PF07655.8 ETO21543.1 - 0.0065 16.8 10.5 0.0065 16.8 7.3 2.1 2 0 0 2 2 2 1 Secretin N-terminal domain AAA_16 PF13191.1 ETO21543.1 - 0.058 13.3 0.1 0.88 9.5 0.0 2.4 1 1 0 1 1 1 0 AAA ATPase domain MAGE PF01454.14 ETO21544.1 - 0.026 13.8 1.0 0.029 13.6 0.7 1.1 1 0 0 1 1 1 0 MAGE family SR-25 PF10500.4 ETO21544.1 - 2.8 7.3 11.1 0.22 10.9 2.6 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Fmp27 PF10344.4 ETO21544.1 - 6.5 4.3 10.3 0.042 11.5 0.8 1.7 1 1 1 2 2 2 0 Mitochondrial protein from FMP27 Cas_DxTHG PF09455.5 ETO21544.1 - 7 5.6 8.4 8 5.4 5.8 1.0 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family PH_8 PF15409.1 ETO21544.1 - 9.3 6.3 8.8 0.9 9.6 1.3 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain DUF3128 PF11326.3 ETO21544.1 - 9.7 6.3 9.0 7.3 6.7 4.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) TPR_19 PF14559.1 ETO21545.1 - 0.031 14.6 6.1 2.1 8.7 0.1 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 ETO21545.1 - 6 7.0 8.6 2.8 8.1 0.1 3.6 3 2 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 DAO PF01266.19 ETO21546.1 - 3.1e-24 85.5 0.0 5.5e-21 74.8 0.0 2.0 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETO21546.1 - 0.00048 19.0 0.0 0.00074 18.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 ETO21546.1 - 0.006 15.7 0.0 0.0092 15.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 ETO21546.1 - 0.035 13.1 0.0 0.049 12.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain TctB PF07331.6 ETO21547.1 - 0.28 10.8 12.4 3 7.5 3.9 2.9 2 1 1 3 3 3 0 Tripartite tricarboxylate transporter TctB family DUF4131 PF13567.1 ETO21547.1 - 5.7 6.3 11.5 0.33 10.3 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Thioredoxin PF00085.15 ETO21548.1 - 1e-20 73.3 0.1 2.5e-20 72.1 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin Globin PF00042.17 ETO21548.1 - 2.7e-12 46.9 2.3 1.8e-08 34.6 0.2 2.9 2 0 0 2 2 2 2 Globin COPIIcoated_ERV PF07970.7 ETO21548.1 - 3.8e-08 33.2 0.2 9e-05 22.1 0.0 2.6 1 1 1 2 2 2 2 Endoplasmic reticulum vesicle transporter Thioredoxin_8 PF13905.1 ETO21548.1 - 7.4e-05 22.7 0.1 0.00044 20.3 0.1 2.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 ETO21548.1 - 0.017 15.3 0.2 0.18 11.9 0.1 2.6 1 1 0 1 1 1 0 Thioredoxin-like domain zf-Apc11 PF12861.2 ETO21549.1 - 0.032 14.0 0.8 0.032 14.0 0.6 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.2 ETO21549.1 - 0.29 10.9 5.8 1.5 8.6 0.3 2.3 2 0 0 2 2 2 0 Double zinc ribbon IBR PF01485.16 ETO21549.1 - 1.8 8.4 10.2 7.4 6.5 7.1 1.9 1 1 0 1 1 1 0 IBR domain Methyltransf_16 PF10294.4 ETO21550.1 - 1.4e-15 57.1 2.6 8.6e-11 41.5 0.2 2.4 1 1 1 2 2 2 2 Putative methyltransferase MTS PF05175.9 ETO21550.1 - 6.1e-06 25.7 0.0 1.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 ETO21550.1 - 3.7e-05 23.3 5.6 0.0011 18.5 0.2 2.5 1 1 1 2 2 2 2 Methyltransferase domain PrmA PF06325.8 ETO21550.1 - 0.00064 18.9 0.2 0.0014 17.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 ETO21550.1 - 0.00083 19.7 1.4 0.0094 16.4 0.4 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETO21550.1 - 0.001 19.4 0.4 0.0044 17.3 0.1 2.4 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETO21550.1 - 0.0016 18.1 0.1 0.0052 16.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETO21550.1 - 0.0019 18.6 0.3 0.032 14.7 0.0 2.9 3 1 0 3 3 2 1 Methyltransferase domain PCMT PF01135.14 ETO21550.1 - 0.0034 16.9 0.0 0.0053 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 ETO21550.1 - 0.0048 17.4 0.0 0.0092 16.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 ETO21550.1 - 0.007 15.9 0.1 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 ETO21550.1 - 0.051 13.6 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF4464 PF14713.1 ETO21551.1 - 8.1e-78 261.0 8.7 1.7e-59 201.0 2.6 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4464) Rho_GDI PF02115.12 ETO21551.1 - 0.024 14.0 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 RHO protein GDP dissociation inhibitor Hydrolase_6 PF13344.1 ETO21553.1 - 7.1e-14 51.5 0.0 1.9e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase OCIA PF07051.6 ETO21553.1 - 0.0019 17.6 0.1 0.0043 16.4 0.1 1.6 1 0 0 1 1 1 1 Ovarian carcinoma immunoreactive antigen (OCIA) RP-C_C PF11800.3 ETO21557.1 - 0.16 11.6 1.2 0.22 11.1 0.8 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region CBFD_NFYB_HMF PF00808.18 ETO21559.1 - 0.12 12.4 1.1 0.26 11.3 0.0 2.1 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TRM13 PF05206.9 ETO21560.1 - 0.056 12.6 0.0 0.097 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase TRM13 DUF755 PF05501.6 ETO21560.1 - 2.4 8.2 6.0 2.9 7.9 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF755) AAA_13 PF13166.1 ETO21562.1 - 0.0042 15.6 0.9 0.0044 15.5 0.6 1.0 1 0 0 1 1 1 1 AAA domain CCDC155 PF14662.1 ETO21562.1 - 0.0053 16.3 1.7 0.0064 16.1 1.2 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 bZIP_1 PF00170.16 ETO21562.1 - 0.0081 16.1 1.4 0.015 15.2 0.3 1.8 1 1 1 2 2 2 1 bZIP transcription factor TMF_TATA_bd PF12325.3 ETO21562.1 - 0.011 15.4 1.6 0.015 15.0 1.1 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.4 ETO21562.1 - 0.014 15.2 0.8 0.018 14.9 0.6 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 ETO21562.1 - 0.015 13.0 1.9 0.017 12.8 1.3 1.0 1 0 0 1 1 1 0 Myosin tail DUF3450 PF11932.3 ETO21562.1 - 0.015 14.5 0.0 0.019 14.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Atg14 PF10186.4 ETO21562.1 - 0.02 13.8 0.1 0.025 13.5 0.1 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Prefoldin_2 PF01920.15 ETO21562.1 - 0.02 14.6 3.3 0.046 13.4 0.6 2.0 1 1 1 2 2 2 0 Prefoldin subunit Tektin PF03148.9 ETO21562.1 - 0.03 12.8 0.7 0.033 12.7 0.5 1.2 1 0 0 1 1 1 0 Tektin family Seryl_tRNA_N PF02403.17 ETO21562.1 - 0.034 14.1 0.5 0.044 13.7 0.3 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF869 PF05911.6 ETO21562.1 - 0.035 12.3 0.6 0.037 12.2 0.4 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) DUF2413 PF10310.4 ETO21562.1 - 0.038 12.8 0.3 0.044 12.5 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Tropomyosin_1 PF12718.2 ETO21562.1 - 0.041 13.7 0.3 0.052 13.3 0.2 1.1 1 0 0 1 1 1 0 Tropomyosin like Nsp1_C PF05064.8 ETO21562.1 - 0.046 13.3 0.7 0.059 13.0 0.5 1.2 1 0 0 1 1 1 0 Nsp1-like C-terminal region DUF4201 PF13870.1 ETO21562.1 - 0.064 12.6 1.1 0.091 12.1 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) NPV_P10 PF05531.7 ETO21562.1 - 0.067 13.4 0.3 0.088 13.0 0.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 ETO21562.1 - 0.072 12.6 0.5 0.087 12.4 0.4 1.2 1 0 0 1 1 1 0 IncA protein TBPIP PF07106.8 ETO21562.1 - 0.095 12.2 1.5 0.12 11.9 0.8 1.3 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) YscO PF07321.7 ETO21562.1 - 0.099 12.4 1.0 0.12 12.1 0.7 1.1 1 0 0 1 1 1 0 Type III secretion protein YscO BLOC1_2 PF10046.4 ETO21562.1 - 0.11 12.6 0.5 0.15 12.1 0.3 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Dad2 PF08654.5 ETO21562.1 - 0.13 12.2 0.9 0.25 11.3 0.5 1.4 1 1 1 2 2 2 0 DASH complex subunit Dad2 DivIC PF04977.10 ETO21562.1 - 0.15 11.5 2.0 1.2 8.6 1.3 2.0 1 1 0 1 1 1 0 Septum formation initiator bZIP_Maf PF03131.12 ETO21562.1 - 0.15 12.3 0.8 0.33 11.2 0.2 1.7 1 1 1 2 2 2 0 bZIP Maf transcription factor H-kinase_dim PF02895.9 ETO21562.1 - 0.16 12.3 1.2 0.26 11.6 0.8 1.4 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain TMF_DNA_bd PF12329.3 ETO21562.1 - 0.63 9.8 4.6 1.2 8.9 3.2 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding FA_hydroxylase PF04116.8 ETO21563.1 - 1.3e-11 44.9 4.4 1.3e-11 44.9 3.1 3.0 2 2 0 2 2 2 1 Fatty acid hydroxylase superfamily NIF PF03031.13 ETO21566.1 - 9.4e-09 35.1 0.0 2.1e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF2457 PF10446.4 ETO21566.1 - 2.8e-06 26.3 25.8 3.8e-06 25.9 17.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Cwf_Cwc_15 PF04889.7 ETO21566.1 - 0.0015 18.3 19.1 0.002 17.8 13.2 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Drc1-Sld2 PF11719.3 ETO21566.1 - 0.027 13.5 9.4 0.033 13.3 6.5 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein FLO_LFY PF01698.11 ETO21566.1 - 0.042 12.6 9.3 0.055 12.3 6.5 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Spc7_N PF15402.1 ETO21566.1 - 0.049 11.6 13.5 0.066 11.2 9.4 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Daxx PF03344.10 ETO21566.1 - 0.33 9.3 13.9 0.49 8.8 9.6 1.3 1 0 0 1 1 1 0 Daxx Family CENP-B_dimeris PF09026.5 ETO21566.1 - 1.3 9.3 20.8 0.13 12.5 10.9 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF1682 PF07946.9 ETO21566.1 - 1.7 7.4 9.5 2.1 7.1 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) ATG27 PF09451.5 ETO21566.1 - 1.9 7.6 7.4 2.8 7.1 5.1 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 BUD22 PF09073.5 ETO21566.1 - 2.7 6.9 18.0 3.7 6.5 12.4 1.1 1 0 0 1 1 1 0 BUD22 Astro_capsid PF03115.9 ETO21566.1 - 5.9 5.0 9.6 6.7 4.8 6.6 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Osteopontin PF00865.13 ETO21566.1 - 7.7 5.6 23.7 11 5.1 16.4 1.3 1 0 0 1 1 1 0 Osteopontin Kinesin PF00225.18 ETO21569.1 - 7.6e-67 225.3 4.3 2.2e-41 141.6 0.0 3.2 2 1 1 3 3 3 3 Kinesin motor domain HHA PF05321.6 ETO21569.1 - 0.18 11.9 0.7 20 5.4 0.0 3.0 3 0 0 3 3 3 0 Haemolysin expression modulating protein TMF_DNA_bd PF12329.3 ETO21569.1 - 0.23 11.3 7.9 0.59 9.9 1.9 2.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.7 ETO21569.1 - 0.84 10.0 7.1 1.2 9.5 1.8 2.7 2 0 0 2 2 2 0 SlyX Pkinase PF00069.20 ETO21570.1 - 1e-64 218.2 0.1 2.5e-64 216.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO21570.1 - 2.3e-28 98.9 0.0 5.3e-28 97.7 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.24 ETO21570.1 - 3e-11 42.9 0.0 5.8e-06 26.0 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Kinase-like PF14531.1 ETO21570.1 - 0.0017 17.3 0.0 0.0049 15.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like fn1 PF00039.13 ETO21570.1 - 0.096 12.5 0.5 0.34 10.7 0.4 1.9 1 0 0 1 1 1 0 Fibronectin type I domain APH PF01636.18 ETO21570.1 - 0.098 12.3 0.0 0.59 9.8 0.0 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family Baculo_11_kDa PF06143.6 ETO21571.1 - 0.0023 17.2 0.3 0.0046 16.2 0.2 1.5 1 0 0 1 1 1 1 Baculovirus 11 kDa family 7tm_1 PF00001.16 ETO21571.1 - 0.077 12.1 0.0 0.079 12.0 0.0 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF4446 PF14584.1 ETO21571.1 - 0.14 12.0 4.9 0.13 12.0 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF4407 PF14362.1 ETO21571.1 - 0.21 10.5 1.5 0.27 10.1 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Vma12 PF11712.3 ETO21571.1 - 0.35 10.5 2.4 0.33 10.6 0.5 1.6 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase APC_CDC26 PF10471.4 ETO21571.1 - 0.71 10.6 10.9 4 8.2 2.2 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 RFXA_RFXANK_bdg PF15289.1 ETO21571.1 - 0.75 10.0 6.5 2.9 8.1 0.7 2.1 2 0 0 2 2 2 0 Regulatory factor X-associated C-terminal binding domain Neur_chan_memb PF02932.11 ETO21571.1 - 4.9 6.9 6.5 0.64 9.8 1.0 1.8 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Ly49 PF08391.5 ETO21571.1 - 6.6 6.9 11.0 1.2 9.2 1.9 2.1 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region CRF1 PF10380.4 ETO21572.1 - 0.0076 16.5 0.7 0.017 15.4 0.4 1.7 1 1 0 1 1 1 1 Transcription factor CRF1 SprA-related PF12118.3 ETO21572.1 - 0.016 14.5 26.9 0.02 14.2 18.6 1.0 1 0 0 1 1 1 0 SprA-related family UPF0560 PF10577.4 ETO21572.1 - 0.022 13.0 12.5 0.025 12.8 8.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF2981 PF11200.3 ETO21572.1 - 0.22 10.5 6.5 0.28 10.2 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Suf PF05843.9 ETO21572.1 - 0.71 9.5 12.9 0.93 9.1 9.0 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DivIC PF04977.10 ETO21572.1 - 0.76 9.3 10.4 1.4 8.4 7.2 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF4220 PF13968.1 ETO21572.1 - 0.86 8.6 7.5 1 8.3 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Med15 PF09606.5 ETO21572.1 - 0.91 7.6 30.0 1.1 7.3 20.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2215 PF10225.4 ETO21572.1 - 1.5 8.1 6.0 1.6 8.1 4.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) FAM60A PF15396.1 ETO21572.1 - 3.1 7.4 12.5 3.9 7.1 8.7 1.3 1 0 0 1 1 1 0 Protein Family FAM60A DUF4175 PF13779.1 ETO21572.1 - 3.4 5.2 22.9 3.9 5.0 15.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Paramyxo_ncap PF00973.14 ETO21572.1 - 9.3 4.8 12.6 10 4.6 8.8 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Pkinase PF00069.20 ETO21575.1 - 2.8e-17 62.7 0.3 5.9e-17 61.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO21575.1 - 3.8e-09 36.0 0.0 6.5e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Cnd2 PF05786.9 ETO21575.1 - 0.0017 17.0 2.5 0.0023 16.5 1.7 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 Nucleoplasmin PF03066.10 ETO21575.1 - 0.0027 17.2 4.6 0.0044 16.5 3.2 1.3 1 0 0 1 1 1 1 Nucleoplasmin HSP90 PF00183.13 ETO21575.1 - 0.0085 14.5 8.0 0.013 13.9 5.5 1.2 1 0 0 1 1 1 1 Hsp90 protein Myc_N PF01056.13 ETO21575.1 - 0.0099 15.0 3.3 0.014 14.5 2.3 1.2 1 0 0 1 1 1 1 Myc amino-terminal region TFIIF_alpha PF05793.7 ETO21575.1 - 0.012 13.9 9.8 0.018 13.4 6.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2890 PF11081.3 ETO21575.1 - 0.016 15.2 4.9 0.029 14.4 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) YqfQ PF14181.1 ETO21575.1 - 0.15 12.0 4.6 0.25 11.3 3.2 1.3 1 0 0 1 1 1 0 YqfQ-like protein Cytomega_UL84 PF06284.6 ETO21575.1 - 0.2 10.0 1.4 0.35 9.2 1.0 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein RNase_H2-Ydr279 PF09468.5 ETO21575.1 - 0.24 10.5 4.0 0.39 9.8 2.8 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Tom37_C PF11801.3 ETO21575.1 - 0.28 11.0 4.1 1.7 8.4 0.8 2.8 3 0 0 3 3 3 0 Tom37 C-terminal domain FAM176 PF14851.1 ETO21575.1 - 0.51 10.0 4.6 0.99 9.0 3.2 1.5 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.9 ETO21575.1 - 0.71 7.8 7.6 0.23 9.4 2.9 1.8 2 0 0 2 2 2 0 CDC45-like protein RNA_pol_Rpc4 PF05132.9 ETO21575.1 - 1.5 8.8 5.9 2.6 8.0 4.1 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 PBP1_TM PF14812.1 ETO21575.1 - 2 8.7 8.9 5.5 7.3 6.2 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_60s PF00428.14 ETO21575.1 - 5.3 7.5 13.5 14 6.1 9.4 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF2975 PF11188.3 ETO21577.1 - 4.4 7.0 8.6 5.4 6.7 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) DUF3021 PF11457.3 ETO21577.1 - 6.2 6.6 10.7 3.7 7.4 3.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3021) PH PF00169.24 ETO21578.1 - 2.2e-07 31.0 4.6 4.4e-07 30.0 0.1 3.7 3 0 0 3 3 3 1 PH domain PH_11 PF15413.1 ETO21578.1 - 6.4e-05 23.1 0.2 6.4e-05 23.1 0.1 4.7 3 1 1 4 4 4 1 Pleckstrin homology domain DUF2362 PF10154.4 ETO21579.1 - 0.01 14.5 9.1 0.013 14.2 6.3 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) IncA PF04156.9 ETO21580.1 - 0.043 13.4 2.7 0.093 12.3 1.9 1.7 1 1 0 1 1 1 0 IncA protein DUF1158 PF06643.6 ETO21580.1 - 0.25 11.6 2.0 0.43 10.9 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1158) UPF0560 PF10577.4 ETO21580.1 - 0.92 7.6 9.3 1.2 7.2 6.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 CDC45 PF02724.9 ETO21580.1 - 0.99 7.3 19.2 1.5 6.7 13.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.11 ETO21580.1 - 1.2 9.0 9.3 2.2 8.1 6.4 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.2 ETO21580.1 - 9.6 3.7 13.4 13 3.3 9.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Mtc PF03820.12 ETO21581.1 - 2.3e-37 128.3 0.4 8.8e-37 126.3 0.3 1.7 1 1 0 1 1 1 1 Tricarboxylate carrier Orbi_NS3 PF01616.11 ETO21582.1 - 0.36 9.7 1.8 0.57 9.1 1.2 1.3 1 0 0 1 1 1 0 Orbivirus NS3 DUF2116 PF09889.4 ETO21582.1 - 0.43 10.4 4.8 0.24 11.2 0.3 2.5 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) TMEM237 PF15383.1 ETO21582.1 - 0.59 9.2 8.5 0.11 11.5 1.1 2.2 1 1 1 2 2 2 0 Transmembrane protein 237 CHD5 PF04420.9 ETO21582.1 - 3.3 7.3 8.8 0.83 9.2 1.3 2.5 1 1 1 3 3 3 0 CHD5-like protein EpsG PF14897.1 ETO21582.1 - 4.1 6.2 38.2 0.035 13.0 14.1 2.1 1 1 1 2 2 2 0 EpsG family AA_permease_2 PF13520.1 ETO21582.1 - 4.6 5.6 22.1 0.11 10.9 6.1 2.4 1 1 2 3 3 3 0 Amino acid permease 7tm_3 PF00003.17 ETO21585.1 - 2.1e-06 27.2 10.8 2.1e-06 27.2 7.5 1.8 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR DASH_Ask1 PF08655.5 ETO21585.1 - 0.045 13.5 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 DASH complex subunit Ask1 Pkinase PF00069.20 ETO21586.1 - 1e-22 80.5 0.3 1.1e-10 41.1 0.1 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO21586.1 - 1.2e-06 27.7 0.2 0.008 15.2 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase DUF2645 PF10840.3 ETO21586.1 - 0.06 13.5 0.6 0.1 12.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2645) tRNA-synt_2b PF00587.20 ETO21588.1 - 3.6e-19 68.9 0.1 6.3e-19 68.2 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.10 ETO21588.1 - 5.5e-08 32.7 0.0 9.3e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain DUF1116 PF06545.6 ETO21588.1 - 0.12 11.4 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1116) Cellulase PF00150.13 ETO21589.1 - 8.6e-07 28.4 0.4 1.3e-06 27.7 0.3 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DSPc PF00782.15 ETO21590.1 - 7.9e-14 51.3 0.2 7.9e-14 51.3 0.1 2.8 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain RabGAP-TBC PF00566.13 ETO21591.1 - 5.7e-06 25.9 0.0 9.2e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain AAA_12 PF13087.1 ETO21592.1 - 1.7e-46 158.1 2.2 1.6e-45 154.9 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.1 ETO21592.1 - 3.6e-39 134.7 0.1 3.6e-39 134.7 0.1 2.4 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 ETO21592.1 - 1.2e-07 31.4 0.1 0.0056 16.2 0.0 3.7 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 ETO21592.1 - 2.2e-07 30.6 0.0 0.051 13.1 0.0 3.1 2 1 1 3 3 3 2 AAA domain AAA_19 PF13245.1 ETO21592.1 - 2.7e-06 27.0 0.0 7.3e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 ETO21592.1 - 0.00021 21.4 0.1 0.17 12.0 0.0 3.8 3 2 0 3 3 3 1 AAA domain DUF2075 PF09848.4 ETO21592.1 - 0.00065 18.7 0.0 0.18 10.7 0.0 3.5 4 0 0 4 4 4 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 ETO21592.1 - 0.0057 16.8 0.4 0.061 13.5 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 ETO21592.1 - 0.0067 16.7 0.2 0.21 11.9 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 ETO21592.1 - 0.017 14.8 0.0 0.089 12.5 0.0 2.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 ETO21592.1 - 0.018 14.6 0.0 0.057 13.0 0.0 1.9 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 ETO21592.1 - 0.019 14.9 0.0 0.07 13.1 0.0 2.0 2 0 0 2 2 1 0 AAA ATPase domain UvrD_C_2 PF13538.1 ETO21592.1 - 0.023 14.8 0.1 0.14 12.3 0.0 2.4 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain ResIII PF04851.10 ETO21592.1 - 0.33 10.7 5.2 0.61 9.8 1.4 3.1 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DOMON PF03351.12 ETO21593.1 - 8.8e-08 32.1 1.4 1.4e-07 31.4 1.0 1.3 1 0 0 1 1 1 1 DOMON domain AAA PF00004.24 ETO21594.1 - 1.8e-37 128.4 0.0 4.6e-37 127.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 ETO21594.1 - 1.1e-05 25.2 0.0 3.4e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.7 ETO21594.1 - 1.5e-05 24.1 0.0 3.4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 ETO21594.1 - 3.6e-05 23.8 0.1 0.0028 17.8 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 ETO21594.1 - 0.0012 18.5 0.0 0.007 16.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 ETO21594.1 - 0.0052 15.9 0.6 0.013 14.7 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 ETO21594.1 - 0.0096 14.6 0.0 0.023 13.4 0.0 1.6 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 ETO21594.1 - 0.032 14.2 0.5 0.47 10.4 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 ETO21594.1 - 0.042 13.7 0.0 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 ETO21594.1 - 0.079 12.7 0.4 0.24 11.1 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain IstB_IS21 PF01695.12 ETO21594.1 - 0.08 12.3 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein FdhE PF04216.7 ETO21595.1 - 0.003 17.3 1.8 0.0031 17.2 0.6 1.5 1 1 0 1 1 1 1 Protein involved in formate dehydrogenase formation DUF2628 PF10947.3 ETO21595.1 - 0.044 13.5 0.2 0.09 12.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) Sigma70_ner PF04546.8 ETO21595.1 - 0.66 9.5 21.8 0.039 13.5 8.7 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region YqeY PF09424.5 ETO21595.1 - 2.6 7.8 14.7 2.6 7.8 2.4 3.4 3 1 0 3 3 3 0 Yqey-like protein Vfa1 PF08432.5 ETO21595.1 - 8.5 6.3 20.1 0.77 9.7 8.3 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Sporozoite_P67 PF05642.6 ETO21595.1 - 8.9 4.0 8.6 15 3.3 6.0 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PAT1 PF09770.4 ETO21596.1 - 6e-06 24.8 3.3 6e-06 24.8 2.3 3.2 3 0 0 3 3 3 2 Topoisomerase II-associated protein PAT1 RolB_RolC PF02027.12 ETO21596.1 - 0.0015 17.7 0.2 0.069 12.3 0.0 2.6 2 0 0 2 2 2 2 RolB/RolC glucosidase family FAM176 PF14851.1 ETO21597.1 - 0.072 12.7 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 FAM176 family PRP1_N PF06424.7 ETO21597.1 - 0.14 12.5 2.3 0.24 11.7 1.6 1.4 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DltD_M PF04918.7 ETO21597.1 - 1.1 9.4 6.4 1.7 8.8 3.9 1.7 1 1 0 1 1 1 0 DltD central region FA_desaturase PF00487.19 ETO21599.1 - 5.4e-14 52.2 7.3 7.2e-14 51.8 5.1 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Asparaginase_2 PF01112.13 ETO21600.1 - 3.7e-71 239.4 0.5 5.2e-63 212.6 0.3 2.1 2 0 0 2 2 2 2 Asparaginase Peptidase_M16_C PF05193.16 ETO21601.1 - 1.5e-07 31.2 0.0 2.3e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Kelch_4 PF13418.1 ETO21604.1 - 0.0023 17.6 4.9 0.014 15.1 0.1 4.0 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO21604.1 - 0.022 14.2 6.0 4.8 6.8 0.0 4.6 5 0 0 5 5 5 0 Kelch motif Kelch_2 PF07646.10 ETO21604.1 - 0.03 14.1 2.2 1.4 8.8 0.0 3.8 4 0 0 4 4 4 0 Kelch motif Kelch_6 PF13964.1 ETO21604.1 - 0.058 13.5 1.9 1.9 8.8 0.0 3.9 3 0 0 3 3 3 0 Kelch motif zf-MYND PF01753.13 ETO21605.1 - 4.8e-09 35.9 13.8 9.7e-09 34.9 9.6 1.6 1 0 0 1 1 1 1 MYND finger MtaB PF12176.3 ETO21606.1 - 0.023 13.1 1.2 0.03 12.7 0.7 1.3 1 1 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit PcF PF09461.5 ETO21606.1 - 0.033 14.0 1.0 0.073 12.9 0.7 1.5 1 0 0 1 1 1 0 Phytotoxin PcF protein Phage_sheath_1 PF04984.9 ETO21606.1 - 0.1 11.0 0.5 0.11 10.9 0.4 1.1 1 0 0 1 1 1 0 Phage tail sheath protein Syntaxin-18_N PF10496.4 ETO21606.1 - 0.12 12.2 0.1 0.12 12.2 0.1 1.9 2 1 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus Ly49 PF08391.5 ETO21606.1 - 1.2 9.2 5.7 2.2 8.4 3.8 1.7 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region Macoilin PF09726.4 ETO21606.1 - 1.4 7.0 11.2 1.6 6.9 7.8 1.0 1 0 0 1 1 1 0 Transmembrane protein Uds1 PF15456.1 ETO21606.1 - 3.9 7.4 6.7 3.5 7.6 2.7 1.9 1 1 1 2 2 2 0 Up-regulated During Septation B56 PF01603.15 ETO21607.1 - 9.1e-48 162.8 6.4 1.1e-37 129.6 0.4 2.1 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) Tox-SGS PF15651.1 ETO21608.1 - 0.072 12.8 0.9 0.15 11.8 0.1 1.9 2 0 0 2 2 2 0 Salivary glad secreted protein domain toxin DUF904 PF06005.7 ETO21608.1 - 2.8 8.3 7.5 1.4 9.2 3.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF904) TPD PF14811.1 ETO21609.1 - 0.024 14.1 0.1 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function TPD sequence-motif SR-25 PF10500.4 ETO21609.1 - 0.16 11.3 3.9 0.26 10.7 2.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4642 PF15484.1 ETO21610.1 - 0.0048 16.8 2.4 0.0064 16.4 1.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4642) PBP1_TM PF14812.1 ETO21610.1 - 0.21 11.8 2.9 0.4 11.0 2.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2098 PF09871.4 ETO21610.1 - 1.3 9.0 7.5 2.7 8.0 5.1 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) NMD3 PF04981.8 ETO21611.1 - 0.07 12.2 0.8 3.2 6.7 0.0 2.1 2 0 0 2 2 2 0 NMD3 family Atg14 PF10186.4 ETO21614.1 - 0.011 14.6 10.0 0.015 14.2 6.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 ETO21614.1 - 0.041 13.4 10.9 0.051 13.1 6.4 1.8 1 1 1 2 2 2 0 IncA protein DMPK_coil PF08826.5 ETO21614.1 - 0.22 11.4 6.3 1.2 9.0 0.0 2.9 3 0 0 3 3 3 0 DMPK coiled coil domain like DUF972 PF06156.8 ETO21614.1 - 0.38 11.1 10.3 0.04 14.2 1.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Snapin_Pallidin PF14712.1 ETO21614.1 - 2.3 8.5 8.3 0.37 11.1 2.6 2.0 1 1 1 2 2 2 0 Snapin/Pallidin TMF_DNA_bd PF12329.3 ETO21614.1 - 7.6 6.4 12.1 0.45 10.3 2.2 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Vitellogenin_N PF01347.17 ETO21615.1 - 0.013 13.7 1.2 0.014 13.6 0.8 1.0 1 0 0 1 1 1 0 Lipoprotein amino terminal region Patched PF02460.13 ETO21615.1 - 0.073 10.9 0.8 0.082 10.8 0.6 1.0 1 0 0 1 1 1 0 Patched family RXT2_N PF08595.6 ETO21615.1 - 0.11 12.2 3.3 0.21 11.4 2.3 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2183 PF09949.4 ETO21615.1 - 0.23 11.3 0.1 0.23 11.3 0.1 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) BEX PF04538.7 ETO21615.1 - 3.4 7.9 8.8 9.1 6.5 2.4 2.1 2 0 0 2 2 2 0 Brain expressed X-linked like family BSP_II PF05432.6 ETO21615.1 - 4.7 6.3 8.1 6 6.0 5.6 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) SecY PF00344.15 ETO21616.1 - 4.1e-37 127.9 2.4 5e-37 127.6 1.7 1.0 1 0 0 1 1 1 1 SecY translocase Cytochrom_B_N PF00033.14 ETO21616.1 - 0.11 11.8 0.3 6.9 5.9 0.1 2.2 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Cupin_8 PF13621.1 ETO21617.1 - 1.9e-11 43.9 0.2 3e-11 43.3 0.1 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 ETO21617.1 - 3.1e-10 39.7 0.1 3.8e-10 39.5 0.1 1.1 1 0 0 1 1 1 1 Cupin superfamily protein Peroxin-22 PF12827.2 ETO21617.1 - 0.0068 16.1 0.2 0.011 15.4 0.1 1.3 1 0 0 1 1 1 1 Peroxisomal biogenesis protein family JmjC PF02373.17 ETO21617.1 - 0.062 13.5 0.9 0.22 11.7 0.1 2.3 2 1 0 2 2 2 0 JmjC domain, hydroxylase Cupin_2 PF07883.6 ETO21617.1 - 0.072 12.6 0.1 0.26 10.8 0.0 2.0 3 0 0 3 3 3 0 Cupin domain Parvo_coat PF00740.13 ETO21618.1 - 0.042 12.8 14.6 0.073 12.0 10.1 1.3 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Ndc1_Nup PF09531.5 ETO21618.1 - 0.13 10.6 9.3 0.16 10.3 6.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CDC27 PF09507.5 ETO21618.1 - 0.15 11.2 30.5 0.24 10.5 21.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PAT1 PF09770.4 ETO21618.1 - 0.19 9.9 19.0 0.27 9.4 13.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Senescence_reg PF04520.8 ETO21618.1 - 0.23 11.9 17.7 0.43 11.0 12.2 1.4 1 0 0 1 1 1 0 Senescence regulator NOA36 PF06524.7 ETO21618.1 - 0.92 8.7 7.8 1.8 7.7 5.4 1.4 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.7 ETO21618.1 - 1.2 8.7 22.8 2 8.0 15.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SOBP PF15279.1 ETO21618.1 - 1.8 8.8 16.9 3.3 8.0 11.7 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Dicty_REP PF05086.7 ETO21618.1 - 1.8 6.1 18.8 2.7 5.6 13.1 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF1675 PF07897.6 ETO21618.1 - 5.6 6.7 18.3 8.8 6.0 12.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) GAGA_bind PF06217.7 ETO21618.1 - 8.7 6.2 17.7 15 5.4 12.3 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2207 PF09972.4 ETO21620.1 - 0.13 10.8 10.3 0.0073 14.9 3.4 1.5 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Lin-8 PF03353.10 ETO21620.1 - 0.23 10.7 11.6 0.28 10.4 8.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Hid1 PF12722.2 ETO21620.1 - 0.23 9.0 6.3 0.27 8.8 4.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GEMIN8 PF15348.1 ETO21620.1 - 3.9 7.4 16.9 0.78 9.7 8.9 1.7 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 CDC45 PF02724.9 ETO21620.1 - 7.4 4.4 12.9 8.3 4.3 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.27 ETO21622.1 - 1.6e-11 43.5 0.1 4e-11 42.3 0.0 1.7 2 0 0 2 2 2 1 WD domain, G-beta repeat WD40 PF00400.27 ETO21623.1 - 3e-12 45.9 3.9 5.3e-05 22.9 0.0 3.6 3 1 1 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO21623.1 - 0.019 13.1 0.1 0.025 12.7 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 NACHT PF05729.7 ETO21624.1 - 7.7e-18 64.6 0.0 1.9e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETO21624.1 - 0.091 12.7 0.2 2.2 8.2 0.2 2.5 1 1 0 1 1 1 0 AAA ATPase domain PH_11 PF15413.1 ETO21625.1 - 0.0013 18.9 0.0 0.0013 18.9 0.0 2.8 4 1 0 4 4 4 1 Pleckstrin homology domain PH PF00169.24 ETO21625.1 - 0.0023 18.1 1.4 0.0063 16.7 0.1 2.4 2 2 0 2 2 2 1 PH domain PID_2 PF14719.1 ETO21625.1 - 0.0082 15.7 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Lactamase_B_2 PF12706.2 ETO21626.1 - 1.5e-05 24.6 0.0 2.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Mito_fiss_reg PF05308.6 ETO21626.1 - 0.81 9.0 6.7 1.3 8.3 4.6 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF3439 PF11921.3 ETO21626.1 - 1.1 8.9 13.6 2.9 7.6 9.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Med3 PF11593.3 ETO21626.1 - 1.6 7.8 15.1 2.2 7.4 10.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ribosomal_S30 PF04758.9 ETO21627.1 - 0.36 10.6 2.9 0.8 9.5 2.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S30 Apc15p PF05841.6 ETO21628.1 - 0.3 11.8 9.8 0.41 11.3 6.8 1.2 1 0 0 1 1 1 0 Apc15p protein DUF2242 PF10001.4 ETO21628.1 - 0.39 10.5 2.2 0.55 10.1 1.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2242) HDA2-3 PF11496.3 ETO21628.1 - 0.55 9.0 7.0 0.6 8.8 4.9 1.2 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 DUF4557 PF15101.1 ETO21628.1 - 0.85 9.4 8.0 1 9.1 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) FAM60A PF15396.1 ETO21628.1 - 5 6.8 15.0 5.5 6.6 10.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF4551 PF15087.1 ETO21628.1 - 5.6 5.1 13.8 6.2 5.0 9.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF3332 PF11810.3 ETO21628.1 - 7 6.2 7.3 8.9 5.9 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) LMBR1 PF04791.11 ETO21628.1 - 7.3 5.0 11.1 8 4.9 7.7 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein CUE PF02845.11 ETO21629.1 - 6.3e-12 44.7 0.4 5.7e-07 28.9 0.1 2.4 2 0 0 2 2 2 2 CUE domain PUB PF09409.5 ETO21629.1 - 4.3e-06 26.3 0.3 4.3e-05 23.1 0.2 2.3 1 1 0 1 1 1 1 PUB domain Adenine_glyco PF03352.8 ETO21629.1 - 0.0017 17.8 0.0 0.0039 16.7 0.0 1.8 1 1 0 1 1 1 1 Methyladenine glycosylase HTH_8 PF02954.14 ETO21629.1 - 0.0074 15.8 0.0 0.089 12.3 0.0 2.5 3 0 0 3 3 3 1 Bacterial regulatory protein, Fis family DMA PF03474.9 ETO21629.1 - 0.01 15.6 0.7 0.72 9.7 0.0 2.9 3 0 0 3 3 3 0 DMRTA motif DUF950 PF06106.6 ETO21629.1 - 0.098 12.7 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 Staphylococcus protein of unknown function (DUF950) zf-RING_2 PF13639.1 ETO21630.1 - 1.8e-14 53.2 11.8 1.8e-14 53.2 8.2 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 ETO21630.1 - 4.3e-08 33.1 8.3 4.3e-08 33.1 5.7 1.7 2 0 0 2 2 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 ETO21630.1 - 6e-07 29.0 10.8 6e-07 29.0 7.5 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO21630.1 - 1.5e-06 28.1 10.9 1.5e-06 28.1 7.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO21630.1 - 5.3e-06 26.0 7.0 5.3e-06 26.0 4.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 ETO21630.1 - 4.6e-05 23.1 4.8 0.0001 22.0 3.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 ETO21630.1 - 9.9e-05 21.9 9.2 9.9e-05 21.9 6.4 2.5 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_3 PF14369.1 ETO21630.1 - 0.00013 21.9 0.4 0.00013 21.9 0.3 3.3 3 0 0 3 3 3 2 zinc-finger Rad50_zn_hook PF04423.9 ETO21630.1 - 0.0037 16.6 1.9 0.31 10.5 0.0 3.1 3 0 0 3 3 3 1 Rad50 zinc hook motif zf-RING_UBOX PF13445.1 ETO21630.1 - 0.056 13.1 4.9 0.21 11.3 2.2 2.7 1 1 1 2 2 2 0 RING-type zinc-finger zf-C4 PF00105.13 ETO21630.1 - 0.082 13.1 6.5 0.58 10.4 1.0 2.5 2 0 0 2 2 2 0 Zinc finger, C4 type (two domains) zf-Nse PF11789.3 ETO21630.1 - 0.48 9.9 5.7 1.1 8.8 3.9 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C2H2_4 PF13894.1 ETO21630.1 - 2.3 8.7 9.2 22 5.6 0.1 4.0 4 1 0 4 4 4 0 C2H2-type zinc finger Prok-RING_4 PF14447.1 ETO21630.1 - 4 7.0 13.5 0.91 9.1 0.1 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 ETO21630.1 - 4.8 6.8 16.2 0.22 11.1 6.4 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain VIT1 PF01988.14 ETO21631.1 - 0.2 11.1 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 VIT family SE PF08491.5 ETO21631.1 - 0.21 10.3 1.0 0.39 9.5 0.7 1.3 1 0 0 1 1 1 0 Squalene epoxidase Bromodomain PF00439.20 ETO21632.1 - 3.5e-06 26.8 0.6 3.6e-05 23.5 0.2 2.4 2 0 0 2 2 2 1 Bromodomain Mucin PF01456.12 ETO21632.1 - 0.00038 20.2 0.2 0.00038 20.2 0.1 2.9 3 0 0 3 3 3 1 Mucin-like glycoprotein Serglycin PF04360.7 ETO21632.1 - 0.037 13.7 3.1 0.048 13.4 0.4 2.1 2 0 0 2 2 2 0 Serglycin DUF2192 PF09958.4 ETO21632.1 - 0.066 12.4 0.2 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2192) DUF3439 PF11921.3 ETO21632.1 - 0.79 9.4 12.7 0.032 13.9 4.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 ETO21632.1 - 3.3 5.3 15.1 0.047 11.4 3.5 2.1 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Nop25 PF09805.4 ETO21633.1 - 0.93 9.5 23.4 1.2 9.2 16.2 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF1675 PF07897.6 ETO21633.1 - 1.3 8.8 13.5 1.5 8.6 9.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DDRGK PF09756.4 ETO21633.1 - 2.4 7.5 20.5 2.9 7.2 14.2 1.1 1 0 0 1 1 1 0 DDRGK domain Selenoprotein_S PF06936.6 ETO21633.1 - 2.5 7.5 13.3 3.7 7.0 9.2 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) TP53IP5 PF15331.1 ETO21633.1 - 2.6 7.9 11.4 3.2 7.6 7.9 1.0 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Otopetrin PF03189.8 ETO21633.1 - 3.4 6.5 6.4 3.7 6.4 4.4 1.0 1 0 0 1 1 1 0 Otopetrin Cytadhesin_P30 PF07271.6 ETO21633.1 - 3.6 6.7 6.8 4.3 6.5 4.7 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 Bud13 PF09736.4 ETO21633.1 - 3.8 7.7 17.6 4.7 7.4 12.2 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DHHW PF14286.1 ETO21633.1 - 3.9 6.6 10.8 4.5 6.4 7.5 1.0 1 0 0 1 1 1 0 DHHW protein Peptidase_S64 PF08192.6 ETO21633.1 - 7.5 4.7 10.1 8.6 4.5 7.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 MIP-T3 PF10243.4 ETO21634.1 - 0.25 9.7 26.6 0.33 9.3 18.4 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CENP-B_dimeris PF09026.5 ETO21634.1 - 0.83 9.9 12.9 0.94 9.7 2.5 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Tom22 PF04281.8 ETO21634.1 - 0.96 8.9 13.4 0.49 9.9 1.4 2.4 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Pox_Ag35 PF03286.9 ETO21634.1 - 5 6.5 26.4 0.46 9.9 7.0 2.6 3 0 0 3 3 3 0 Pox virus Ag35 surface protein FAM176 PF14851.1 ETO21634.1 - 7.9 6.1 13.4 6.5 6.4 1.8 2.6 2 0 0 2 2 2 0 FAM176 family SRP54 PF00448.17 ETO21636.1 - 0.018 14.5 0.8 0.031 13.7 0.6 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Phage_lysis PF03245.8 ETO21636.1 - 0.061 13.3 0.1 0.061 13.3 0.0 2.8 2 1 1 3 3 3 0 Bacteriophage Rz lysis protein Menin PF05053.8 ETO21636.1 - 0.078 11.1 10.6 0.098 10.8 7.3 1.4 1 0 0 1 1 1 0 Menin Hid1 PF12722.2 ETO21636.1 - 0.8 7.3 24.3 0.96 7.0 16.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Podoplanin PF05808.6 ETO21636.1 - 1.9 8.0 6.9 3.7 7.1 4.8 1.4 1 0 0 1 1 1 0 Podoplanin PspB PF06667.7 ETO21636.1 - 5.1 7.0 8.1 13 5.7 0.2 2.6 2 0 0 2 2 2 0 Phage shock protein B IncA PF04156.9 ETO21636.1 - 7.6 6.0 16.2 13 5.3 11.3 1.4 1 0 0 1 1 1 0 IncA protein Exostosin PF03016.10 ETO21637.1 - 7.2e-06 25.2 0.0 1.3e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 Exostosin family Enkurin PF13864.1 ETO21637.1 - 0.0074 16.4 1.7 0.015 15.5 0.5 1.9 2 0 0 2 2 2 1 Calmodulin-binding XAP5 PF04921.9 ETO21638.1 - 0.026 14.1 13.7 0.027 14.0 9.5 1.0 1 0 0 1 1 1 0 XAP5, circadian clock regulator DUF908 PF06012.7 ETO21638.1 - 0.61 9.3 7.0 0.64 9.2 4.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) SRP_SPB PF02978.14 ETO21638.1 - 1.6 8.9 8.0 0.16 12.2 2.0 1.8 1 1 1 2 2 2 0 Signal peptide binding domain RNase_H2_suC PF08615.6 ETO21638.1 - 2.6 7.9 10.8 12 5.7 7.5 2.0 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Med15 PF09606.5 ETO21638.1 - 2.7 6.0 19.1 3 5.9 13.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Folate_carrier PF01770.13 ETO21638.1 - 3.7 5.9 6.5 1.7 7.1 3.2 1.3 1 1 0 1 1 1 0 Reduced folate carrier DUF3492 PF11997.3 ETO21638.1 - 4.7 6.6 6.0 5.5 6.4 4.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) BAF1_ABF1 PF04684.8 ETO21638.1 - 5.5 5.7 15.3 5.7 5.6 10.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4484 PF14831.1 ETO21638.1 - 5.6 7.0 10.1 7.5 6.6 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) DUF4456 PF14644.1 ETO21639.1 - 0.0027 16.9 3.8 0.0051 16.0 2.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4456) DUF4612 PF15389.1 ETO21639.1 - 0.35 11.4 5.0 0.66 10.5 3.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4612) DUF1826 PF08856.6 ETO21640.1 - 0.013 15.2 0.4 0.02 14.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1826) 2OG-FeII_Oxy PF03171.15 ETO21640.1 - 0.024 14.9 0.3 0.049 13.9 0.2 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Cullin_binding PF03556.10 ETO21640.1 - 0.035 14.2 0.4 0.066 13.3 0.3 1.5 1 0 0 1 1 1 0 Cullin binding DUF3816 PF12822.2 ETO21641.1 - 0.0018 18.1 0.8 0.0018 18.1 0.5 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3816) PVL_ORF50 PF07768.6 ETO21641.1 - 0.039 13.9 1.8 0.048 13.6 1.3 1.1 1 0 0 1 1 1 0 PVL ORF-50-like family ATG27 PF09451.5 ETO21641.1 - 0.12 11.5 0.3 0.12 11.5 0.2 1.7 2 0 0 2 2 2 0 Autophagy-related protein 27 RGS PF00615.14 ETO21642.1 - 2.7e-11 43.6 1.5 4.6e-11 42.8 1.1 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain DENN PF02141.16 ETO21643.1 - 1.3e-10 41.3 0.8 1.3e-10 41.3 0.6 1.7 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.13 ETO21643.1 - 9.3e-05 22.3 0.3 0.00054 19.8 0.2 2.3 1 1 0 1 1 1 1 uDENN domain NB-ARC PF00931.17 ETO21643.1 - 0.045 12.5 0.0 0.086 11.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ATP-synt_E_2 PF08112.6 ETO21644.1 - 0.66 10.0 4.2 0.82 9.7 0.2 3.0 3 0 0 3 3 3 0 ATP synthase epsilon subunit WGG PF10273.4 ETO21644.1 - 0.68 10.0 2.5 5.6 7.1 0.1 2.6 3 0 0 3 3 3 0 Pre-rRNA-processing protein TSR2 DUF569 PF04601.8 ETO21645.1 - 0.0016 17.9 0.4 0.0034 16.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF569) DUF2914 PF11141.3 ETO21645.1 - 0.054 13.0 0.4 0.16 11.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2914) DUF2335 PF10097.4 ETO21645.1 - 1.4 8.5 0.0 1.4 8.5 0.0 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2335) Paramyxo_ncap PF00973.14 ETO21646.1 - 0.86 8.2 8.3 0.21 10.2 0.4 2.2 2 0 0 2 2 2 0 Paramyxovirus nucleocapsid protein DUF912 PF06024.7 ETO21646.1 - 2.4 8.2 11.0 49 4.0 0.0 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Usp PF00582.21 ETO21647.1 - 0.092 12.9 0.6 13 5.9 0.1 2.3 2 0 0 2 2 2 0 Universal stress protein family Ank_4 PF13637.1 ETO21649.1 - 1.2e-09 38.4 1.3 5.9e-06 26.6 0.3 4.8 6 0 0 6 6 6 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO21649.1 - 1.3e-06 28.6 0.5 0.075 13.3 0.1 3.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO21649.1 - 3.2e-06 26.8 2.7 3.9 8.0 0.1 5.9 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.25 ETO21649.1 - 9e-06 25.2 3.9 0.13 12.1 0.1 5.0 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 ETO21649.1 - 0.0022 18.1 1.1 2 8.8 0.1 4.4 4 0 0 4 4 4 1 Ankyrin repeats (many copies) DUF3324 PF11797.3 ETO21649.1 - 0.13 11.9 0.0 20 4.8 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function C-terminal (DUF3324) DUF3464 PF11947.3 ETO21650.1 - 0.014 14.8 2.4 0.051 13.0 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3464) Eapp_C PF10238.4 ETO21650.1 - 0.09 12.6 2.9 9.3 6.1 0.4 2.5 2 0 0 2 2 2 0 E2F-associated phosphoprotein Peptidase_S49_N PF08496.5 ETO21650.1 - 0.77 9.5 3.1 3.6 7.3 0.2 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal 7TM_GPCR_Str PF10326.4 ETO21651.1 - 0.17 11.0 0.9 0.22 10.6 0.6 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str Secretin_N_2 PF07655.8 ETO21651.1 - 0.96 9.8 9.0 1.7 9.0 6.2 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain WD40 PF00400.27 ETO21653.1 - 1.9e-05 24.3 5.2 0.00019 21.1 0.2 2.9 2 1 0 2 2 2 1 WD domain, G-beta repeat CRT10 PF08728.5 ETO21653.1 - 0.0038 15.3 0.2 0.0045 15.0 0.1 1.0 1 0 0 1 1 1 1 CRT10 HAD PF12710.2 ETO21653.1 - 0.031 14.4 0.1 0.034 14.3 0.1 1.0 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Nup160 PF11715.3 ETO21653.1 - 0.12 10.4 0.1 0.12 10.4 0.0 1.0 1 0 0 1 1 1 0 Nucleoporin Nup120/160 CDT1 PF08839.6 ETO21655.1 - 4.6e-07 29.9 2.6 1.3e-06 28.4 0.2 2.2 2 0 0 2 2 2 1 DNA replication factor CDT1 like DUF3942 PF13078.1 ETO21656.1 - 0.075 13.1 0.4 0.1 12.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3942) Filament PF00038.16 ETO21657.1 - 0.44 9.9 56.6 3.6 6.9 21.5 2.4 1 1 1 2 2 2 0 Intermediate filament protein Pkinase PF00069.20 ETO21658.1 - 3e-15 56.0 0.0 3.5e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO21658.1 - 4.8e-08 32.3 0.0 6e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO21658.1 - 0.041 12.8 0.0 0.042 12.7 0.0 1.2 1 1 0 1 1 1 0 Kinase-like Pkinase PF00069.20 ETO21659.1 - 2e-47 161.5 0.5 2.5e-47 161.2 0.4 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO21659.1 - 8.4e-33 113.5 0.1 1e-32 113.2 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO21659.1 - 0.0011 18.0 0.7 0.0021 17.1 0.5 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO21659.1 - 0.0013 18.4 2.4 0.026 14.2 0.3 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 ETO21659.1 - 0.0046 16.3 0.1 0.0067 15.8 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 ETO21659.1 - 0.011 14.6 0.0 0.19 10.6 0.0 2.1 2 0 0 2 2 2 0 Kinase-like YrbL-PhoP_reg PF10707.4 ETO21659.1 - 0.026 13.8 0.1 0.043 13.1 0.0 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.6 ETO21659.1 - 0.039 12.7 0.0 0.06 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Lipid_DES PF08557.5 ETO21659.1 - 0.066 12.4 1.7 6.9 6.0 0.2 2.6 2 1 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) DNA_pol_A_exo1 PF01612.15 ETO21660.1 - 1.3e-12 47.5 0.1 2.2e-12 46.8 0.0 1.3 1 1 0 1 1 1 1 3'-5' exonuclease Oxidored_q3 PF00499.15 ETO21662.1 - 0.061 13.1 0.1 0.091 12.5 0.1 1.5 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF3278 PF11683.3 ETO21662.1 - 0.26 11.2 3.7 0.26 11.2 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3278) DUF912 PF06024.7 ETO21662.1 - 3.5 7.7 8.0 1.1 9.2 0.9 2.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) EF_assoc_1 PF08355.7 ETO21663.1 - 1.9 7.8 5.8 19 4.6 1.5 2.7 2 1 0 2 2 2 0 EF hand associated BID PF06393.6 ETO21664.1 - 0.06 12.7 0.2 0.071 12.4 0.1 1.2 1 0 0 1 1 1 0 BH3 interacting domain (BID) Myco_arth_vir_N PF09610.5 ETO21665.1 - 0.62 10.0 4.8 1.4 8.9 3.3 1.6 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) DUF4131 PF13567.1 ETO21665.1 - 2.9 7.2 5.0 4.1 6.7 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Fijivirus_P9-2 PF06837.6 ETO21668.1 - 0.029 13.5 7.7 0.041 13.0 5.3 1.2 1 0 0 1 1 1 0 Fijivirus P9-2 protein DUF2207 PF09972.4 ETO21668.1 - 2.9 6.3 5.2 3.3 6.1 3.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TPR_12 PF13424.1 ETO21669.1 - 3.4e-72 238.3 19.0 2.2e-23 81.9 0.6 5.7 2 2 4 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.1 ETO21669.1 - 1.1e-35 120.4 0.0 3.7e-08 33.0 0.0 7.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETO21669.1 - 2.6e-34 116.6 18.6 1.1e-14 53.8 1.9 5.3 4 2 1 5 5 5 4 TPR repeat TPR_2 PF07719.12 ETO21669.1 - 2.5e-26 89.4 27.3 1.2e-05 24.8 0.6 7.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.23 ETO21669.1 - 1e-25 88.2 37.5 8.4e-07 28.3 1.5 7.3 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.1 ETO21669.1 - 5.5e-24 82.0 8.2 2.4e-06 26.9 0.1 7.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO21669.1 - 2.6e-22 76.8 33.7 2.3e-05 23.8 0.3 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 ETO21669.1 - 3.4e-12 46.6 0.8 0.0033 18.0 0.9 4.4 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO21669.1 - 3.5e-10 39.6 7.1 0.29 11.6 0.0 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO21669.1 - 1.1e-09 38.4 0.0 0.0048 17.2 0.0 4.0 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO21669.1 - 1.6e-08 34.0 10.2 2 8.8 0.0 6.7 6 1 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO21669.1 - 4.9e-08 32.9 0.3 1 10.1 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO21669.1 - 2.9e-05 23.2 2.2 0.86 8.9 0.0 5.1 6 0 0 6 6 6 1 SHNi-TPR Apc3 PF12895.2 ETO21669.1 - 7.8e-05 22.7 15.3 0.042 13.9 2.4 4.2 2 2 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 ETO21669.1 - 0.0017 18.1 22.0 0.19 11.5 0.3 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETO21669.1 - 0.0095 15.7 0.1 2.1 8.2 0.1 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat Na_H_antiport_2 PF13726.1 ETO21669.1 - 0.15 11.9 0.0 1.2e+02 2.7 0.0 3.9 4 0 0 4 4 4 0 Na+-H+ antiporter family BSP_II PF05432.6 ETO21669.1 - 0.22 10.7 5.4 0.36 10.0 3.7 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Fis1_TPR_C PF14853.1 ETO21669.1 - 9.1 6.2 16.2 1.7 8.5 0.6 4.9 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat ETF_alpha PF00766.14 ETO21670.1 - 3.9e-35 119.3 0.8 3.9e-35 119.3 0.6 1.9 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 ETO21670.1 - 4e-34 117.6 0.1 6.3e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain NTPase_I-T PF01931.13 ETO21670.1 - 0.029 14.1 0.0 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF84 DUF2877 PF11392.3 ETO21671.1 - 0.012 15.8 0.0 0.03 14.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2877) Baculo_LEF-10 PF07206.6 ETO21671.1 - 0.019 14.5 0.3 0.053 13.1 0.0 2.0 2 0 0 2 2 2 0 Baculovirus late expression factor 10 (LEF-10) Phage_int_SAM_2 PF12834.2 ETO21671.1 - 0.15 12.4 2.1 0.79 10.1 0.0 2.7 2 1 1 3 3 3 0 Phage integrase, N-terminal ABC_tran PF00005.22 ETO21672.1 - 4.1e-25 88.6 0.0 7.6e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 ETO21672.1 - 1.1e-05 24.8 0.1 0.072 12.3 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETO21672.1 - 0.00029 20.8 2.4 0.0079 16.1 0.0 3.1 3 1 0 4 4 3 2 AAA domain NACHT PF05729.7 ETO21672.1 - 0.0014 18.3 0.6 0.14 11.8 0.0 3.4 3 1 1 4 4 4 1 NACHT domain DUF87 PF01935.12 ETO21672.1 - 0.002 18.0 0.1 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_29 PF13555.1 ETO21672.1 - 0.008 15.6 1.3 0.017 14.6 0.8 1.7 1 1 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 ETO21672.1 - 0.011 16.5 0.1 0.035 14.9 0.1 2.2 2 1 0 2 2 1 0 AAA domain AAA_16 PF13191.1 ETO21672.1 - 0.012 15.5 0.1 0.091 12.7 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain Miro PF08477.8 ETO21672.1 - 0.015 15.7 0.0 0.14 12.6 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein AAA_22 PF13401.1 ETO21672.1 - 0.015 15.4 0.0 0.11 12.6 0.0 2.3 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.17 ETO21672.1 - 0.016 15.3 0.2 1.1 9.4 0.0 3.2 3 1 0 3 3 3 0 RNA helicase SbcCD_C PF13558.1 ETO21672.1 - 0.021 14.7 0.0 0.14 12.1 0.0 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 ETO21672.1 - 0.029 14.6 0.1 0.055 13.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 ETO21672.1 - 0.071 12.8 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 ETO21672.1 - 0.073 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 ETO21672.1 - 0.075 12.4 0.2 0.28 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain DUF815 PF05673.8 ETO21672.1 - 0.088 11.7 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ArgK PF03308.11 ETO21672.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 ArgK protein DUF258 PF03193.11 ETO21672.1 - 0.11 11.6 1.4 0.15 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 PIN PF01850.16 ETO21672.1 - 0.14 12.5 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 PIN domain Paf1 PF03985.8 ETO21673.1 - 0.0065 15.2 23.9 0.0094 14.7 16.6 1.1 1 0 0 1 1 1 1 Paf1 CENP-T PF15511.1 ETO21673.1 - 0.21 10.8 12.2 0.25 10.5 8.4 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF3450 PF11932.3 ETO21673.1 - 0.31 10.2 11.1 0.19 10.9 6.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2457 PF10446.4 ETO21673.1 - 0.98 8.0 28.5 1.4 7.5 19.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 ETO21673.1 - 1.6 6.7 20.5 2.1 6.2 14.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2422 PF10337.4 ETO21673.1 - 3.4 6.3 5.1 5.1 5.7 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) RP-C_C PF11800.3 ETO21673.1 - 6.7 6.3 12.2 10 5.7 8.5 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Pkinase PF00069.20 ETO21674.1 - 2.2e-07 30.2 0.0 5.1e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO21674.1 - 0.0057 15.7 0.0 0.0097 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase TFIIF_alpha PF05793.7 ETO21676.1 - 3.3 5.9 23.4 3.5 5.8 16.2 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2967 PF11179.3 ETO21677.1 - 0.024 14.1 0.2 0.024 14.1 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2967) Secretin_N_2 PF07655.8 ETO21678.1 - 0.53 10.7 20.6 0.2 12.0 10.1 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain DAN PF03045.10 ETO21679.1 - 0.011 15.1 0.1 0.011 15.1 0.0 1.8 2 1 0 2 2 2 0 DAN domain PMSR PF01625.16 ETO21680.1 - 1.2e-42 145.4 6.3 3.8e-33 114.5 0.1 2.2 1 1 1 2 2 2 2 Peptide methionine sulfoxide reductase UCH PF00443.24 ETO21681.1 - 1.1e-34 119.8 5.1 2.8e-34 118.4 3.6 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO21681.1 - 2.7e-22 79.5 0.1 2.7e-22 79.5 0.0 1.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 ETO21681.1 - 9.9e-11 41.9 0.2 9.9e-11 41.9 0.1 3.8 3 1 0 3 3 3 1 DUSP domain SprA-related PF12118.3 ETO21681.1 - 3 7.0 24.5 1.2 8.4 12.5 2.4 2 0 0 2 2 2 0 SprA-related family DUF3289 PF11692.3 ETO21682.1 - 0.032 13.4 0.3 0.047 12.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3289) tRNA_anti-like PF12869.2 ETO21682.1 - 0.071 12.5 0.7 0.13 11.7 0.5 1.3 1 0 0 1 1 1 0 tRNA_anti-like DUF3843 PF12954.2 ETO21683.1 - 0.056 12.4 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3843) Nicastrin PF05450.10 ETO21683.1 - 0.11 11.7 0.1 0.21 10.8 0.1 1.5 1 0 0 1 1 1 0 Nicastrin Spt5_N PF11942.3 ETO21683.1 - 0.2 12.2 4.6 0.31 11.6 3.2 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal TPR_12 PF13424.1 ETO21684.1 - 6.5e-35 118.9 12.2 2e-14 53.2 1.6 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO21684.1 - 1.9e-21 75.4 9.6 2.4e-10 39.8 0.1 3.5 3 1 1 4 4 4 2 TPR repeat TPR_1 PF00515.23 ETO21684.1 - 2.2e-17 61.8 20.9 1.2e-05 24.6 0.1 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO21684.1 - 6e-17 60.9 0.2 9.1e-05 22.2 0.0 4.5 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO21684.1 - 1.9e-16 58.5 13.9 0.00031 20.4 0.0 4.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO21684.1 - 7.1e-16 56.6 3.7 4.2e-05 23.0 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO21684.1 - 2.4e-10 39.4 17.9 0.00036 20.0 0.2 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO21684.1 - 1.9e-08 33.8 6.5 0.023 14.8 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO21684.1 - 5.2e-06 26.5 3.3 0.38 11.3 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO21684.1 - 0.00017 21.9 0.0 5.9 7.8 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO21684.1 - 0.00031 21.3 0.9 0.19 12.4 0.0 3.0 2 2 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO21684.1 - 0.00032 20.7 9.3 0.0079 16.3 2.3 3.9 1 1 4 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 ETO21684.1 - 0.72 9.7 4.9 12 5.8 0.1 2.7 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Peptidase_C14 PF00656.17 ETO21685.1 - 8.3e-07 28.9 2.2 0.00046 19.9 0.5 2.4 2 1 0 2 2 2 2 Caspase domain SIS PF01380.17 ETO21686.1 - 2.4e-33 114.5 0.7 2.2e-18 66.1 0.0 3.5 3 0 0 3 3 3 3 SIS domain GATase_6 PF13522.1 ETO21686.1 - 6.3e-22 77.9 0.0 1.3e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 ETO21686.1 - 1.4e-16 60.1 0.3 2.2e-11 43.1 0.1 2.4 2 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_7 PF13537.1 ETO21686.1 - 2.1e-16 59.7 0.0 4e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 ETO21686.1 - 5.3e-05 22.0 0.1 9.7e-05 21.1 0.1 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glyco_tran_28_C PF04101.11 ETO21686.1 - 0.03 13.9 0.0 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain RGS PF00615.14 ETO21687.1 - 7e-05 22.9 6.5 0.0003 20.8 0.4 3.3 3 1 0 3 3 3 2 Regulator of G protein signaling domain DUF2396 PF09654.5 ETO21688.1 - 0.04 13.8 0.2 0.047 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2396) GntR PF00392.16 ETO21688.1 - 0.076 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family DUF919 PF06034.6 ETO21688.1 - 4.6 6.9 7.6 5 6.8 3.6 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) YMF19 PF02326.10 ETO21689.1 - 0.0026 18.2 0.4 0.017 15.6 0.3 2.5 1 0 0 1 1 1 1 Plant ATP synthase F0 zf-MYND PF01753.13 ETO21690.1 - 0.044 13.6 0.9 0.044 13.6 0.6 4.2 4 0 0 4 4 4 0 MYND finger Kelch_1 PF01344.20 ETO21691.1 - 3.4e-05 23.3 0.8 0.00017 21.0 0.0 2.6 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 ETO21691.1 - 6.4e-05 23.0 0.1 0.00039 20.4 0.0 2.4 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO21691.1 - 0.00059 19.9 0.2 0.028 14.5 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETO21691.1 - 0.0049 16.6 0.2 0.078 12.7 0.0 2.7 1 1 1 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO21691.1 - 0.019 14.9 0.5 10 6.1 0.1 2.9 3 0 0 3 3 3 0 Kelch motif Ank_2 PF12796.2 ETO21692.1 - 3e-21 75.5 2.8 6e-11 42.5 0.2 2.1 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO21692.1 - 3.7e-11 43.2 1.3 4.3e-07 30.2 0.1 3.4 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 ETO21692.1 - 6.4e-09 35.1 0.1 0.00085 19.0 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 ETO21692.1 - 1.1e-08 34.9 2.1 7.7e-05 22.8 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO21692.1 - 1.7e-06 27.6 0.4 0.0041 17.2 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Band_7 PF01145.20 ETO21693.1 - 6.5e-08 32.6 1.6 6.2e-07 29.4 0.3 2.3 2 0 0 2 2 2 1 SPFH domain / Band 7 family La PF05383.12 ETO21694.1 - 3.6e-11 42.6 0.0 9.8e-11 41.2 0.0 1.8 1 0 0 1 1 1 1 La domain DUF3439 PF11921.3 ETO21694.1 - 0.015 15.0 1.9 0.031 14.0 1.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) RRM_6 PF14259.1 ETO21694.1 - 0.034 14.1 0.0 0.077 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Tir_receptor_C PF07489.6 ETO21694.1 - 0.46 10.1 5.3 1.3 8.6 3.7 1.7 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus FAM176 PF14851.1 ETO21695.1 - 5.6 6.6 9.4 0.21 11.2 0.8 2.5 3 0 0 3 3 3 0 FAM176 family fn3 PF00041.16 ETO21700.1 - 0.037 14.1 0.2 1.2 9.2 0.0 2.7 3 0 0 3 3 3 0 Fibronectin type III domain GlcNAc PF11397.3 ETO21704.1 - 2e-37 129.1 0.0 1.9e-36 125.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase (GlcNAc) Chromo PF00385.19 ETO21707.1 - 4e-13 48.8 1.3 2e-12 46.5 0.9 2.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DinB PF05163.7 ETO21710.1 - 0.075 12.7 0.0 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 DinB family CRC_subunit PF08624.5 ETO21711.1 - 0.2 11.5 4.6 0.75 9.7 0.0 2.7 3 0 0 3 3 3 0 Chromatin remodelling complex Rsc7/Swp82 subunit Vps35 PF03635.12 ETO21712.1 - 1.2e-68 232.0 4.4 2.4e-68 231.0 3.1 1.4 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DUF2201_N PF13203.1 ETO21712.1 - 0.77 8.8 12.0 0.12 11.5 5.5 1.7 2 0 0 2 2 2 0 Putative metallopeptidase domain CDC45 PF02724.9 ETO21712.1 - 0.99 7.3 10.5 0.35 8.8 5.3 1.7 2 0 0 2 2 2 0 CDC45-like protein TFIIF_alpha PF05793.7 ETO21712.1 - 1.1 7.5 22.3 2 6.6 15.4 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 ETO21712.1 - 1.2 6.9 18.1 1.8 6.3 12.5 1.2 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 ETO21712.1 - 2 7.7 18.1 4.5 6.5 12.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FAD_binding_1 PF00667.15 ETO21714.1 - 5.2e-39 133.9 0.1 5.2e-39 133.9 0.0 2.1 3 0 0 3 3 3 1 FAD binding domain Flavodoxin_1 PF00258.20 ETO21714.1 - 1.3e-14 54.4 0.0 2.6e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin DUF3439 PF11921.3 ETO21714.1 - 0.11 12.3 7.8 0.25 11.1 5.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 ETO21714.1 - 0.13 10.0 4.4 0.18 9.5 3.0 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.6 ETO21714.1 - 0.43 8.5 6.6 0.62 7.9 4.5 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Podoplanin PF05808.6 ETO21714.1 - 1.3 8.5 8.4 3.6 7.1 5.8 1.7 1 0 0 1 1 1 0 Podoplanin NAD_binding_1 PF00175.16 ETO21715.1 - 1.9e-10 41.2 0.1 2.6e-05 24.7 0.0 2.4 1 1 1 2 2 2 2 Oxidoreductase NAD-binding domain Gal-3-0_sulfotr PF06990.6 ETO21715.1 - 0.012 14.2 0.2 0.017 13.8 0.1 1.1 1 0 0 1 1 1 0 Galactose-3-O-sulfotransferase Ank_2 PF12796.2 ETO21716.1 - 1.8e-08 34.5 0.0 6.7e-05 23.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO21716.1 - 5.3e-08 32.8 0.3 0.0012 19.0 0.0 3.7 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO21716.1 - 1.5e-06 28.5 0.0 0.049 14.1 0.1 3.1 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO21716.1 - 5e-06 26.2 1.6 0.84 10.0 0.0 4.1 3 3 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 ETO21716.1 - 1e-05 25.0 0.2 0.24 11.3 0.0 3.9 3 2 0 3 3 3 1 Ankyrin repeat E2_bind PF08825.5 ETO21716.1 - 0.04 13.6 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 E2 binding domain PI3K_rbd PF00794.13 ETO21717.1 - 5.1e-11 42.4 0.0 5.1e-11 42.4 0.0 2.2 3 0 0 3 3 3 1 PI3-kinase family, ras-binding domain TFIIA PF03153.8 ETO21717.1 - 0.019 14.8 1.5 0.023 14.5 1.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3753 PF12575.3 ETO21717.1 - 0.048 13.4 3.6 0.17 11.7 2.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) DUF4634 PF15465.1 ETO21717.1 - 0.074 13.2 0.2 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4634) Rifin_STEVOR PF02009.11 ETO21717.1 - 0.25 10.9 7.1 0.35 10.4 4.6 1.6 1 1 0 1 1 1 0 Rifin/stevor family PI3Ka PF00613.15 ETO21718.1 - 4.9e-44 149.7 0.6 8.2e-44 148.9 0.4 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 ETO21718.1 - 2.5e-36 125.3 0.1 2.5e-36 125.3 0.1 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 ETO21718.1 - 5.9e-17 61.7 0.1 1.6e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 NOA36 PF06524.7 ETO21718.1 - 0.13 11.5 12.6 0.27 10.4 8.7 1.7 1 0 0 1 1 1 0 NOA36 protein FAM196 PF15265.1 ETO21718.1 - 0.59 9.2 11.5 0.85 8.7 7.9 1.1 1 0 0 1 1 1 0 FAM196 family Menin PF05053.8 ETO21718.1 - 1.4 7.0 14.6 2.2 6.3 10.1 1.2 1 0 0 1 1 1 0 Menin Utp14 PF04615.8 ETO21718.1 - 5.1 5.1 16.3 7.4 4.5 11.3 1.1 1 0 0 1 1 1 0 Utp14 protein TPR_12 PF13424.1 ETO21719.1 - 1.2e-69 230.2 44.3 4.4e-22 77.7 3.6 4.6 3 1 3 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETO21719.1 - 7.5e-37 124.2 1.1 1.2e-06 28.2 0.0 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETO21719.1 - 1.2e-34 117.7 50.5 4.3e-12 45.5 7.1 5.1 4 1 2 6 6 6 5 TPR repeat TPR_1 PF00515.23 ETO21719.1 - 8.8e-33 110.5 53.3 8.8e-09 34.6 1.5 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETO21719.1 - 4.4e-31 104.2 43.9 2.4e-07 30.1 1.1 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.1 ETO21719.1 - 2.7e-25 86.1 21.8 6.8e-05 22.3 0.4 6.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 ETO21719.1 - 1.6e-21 74.3 45.8 1.6e-06 27.4 1.1 7.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO21719.1 - 7.8e-17 60.2 6.3 0.0054 17.2 0.0 7.1 7 1 1 8 8 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO21719.1 - 4.3e-15 55.9 9.5 0.00027 21.5 0.3 4.2 4 1 0 4 4 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO21719.1 - 8.4e-11 41.1 19.0 0.0043 17.1 0.2 6.6 5 1 0 5 5 5 3 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO21719.1 - 4e-09 35.5 4.8 0.31 10.3 0.0 6.1 6 0 0 6 6 6 2 SHNi-TPR TPR_6 PF13174.1 ETO21719.1 - 8.4e-08 32.1 25.3 0.003 17.9 0.4 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 ETO21719.1 - 1.3e-07 31.6 30.6 0.00017 21.6 5.4 4.9 1 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO21719.1 - 6.1e-07 29.6 16.3 0.0063 16.8 0.1 4.2 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_3 PF07720.7 ETO21719.1 - 1.6e-05 24.6 2.6 1.6e-05 24.6 1.8 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat DUF2225 PF09986.4 ETO21719.1 - 0.00053 19.5 20.6 0.021 14.2 0.9 3.4 1 1 1 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.13 ETO21719.1 - 0.043 13.6 30.0 1.3 8.9 0.3 7.5 8 0 0 8 8 8 0 MIT (microtubule interacting and transport) domain E6 PF00518.12 ETO21719.1 - 0.097 13.0 1.2 0.19 12.0 0.1 2.1 2 0 0 2 2 1 0 Early Protein (E6) TPR_20 PF14561.1 ETO21719.1 - 0.55 10.3 6.3 26 5.0 0.0 4.4 4 1 1 5 5 4 0 Tetratricopeptide repeat Choline_kinase PF01633.15 ETO21721.1 - 8.8e-40 136.5 13.7 2.6e-39 135.0 9.5 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 ETO21721.1 - 7.6e-05 22.5 0.1 0.00027 20.7 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Leukemia_assc_2 PF15197.1 ETO21722.1 - 0.19 11.4 3.4 0.34 10.6 0.1 2.2 2 0 0 2 2 2 0 Leukemia-associated protein 2 zf-C2H2 PF00096.21 ETO21723.1 - 9.8e-18 63.3 46.4 5.5e-05 23.2 1.9 5.6 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETO21723.1 - 1.7e-14 53.2 36.4 1.2e-05 25.3 1.1 5.8 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 ETO21723.1 - 1.6e-09 37.4 35.7 0.0024 18.0 0.7 5.3 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 ETO21723.1 - 7.6e-09 35.4 36.6 0.00084 19.4 0.2 5.7 5 1 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 ETO21723.1 - 6.2e-06 25.9 34.6 0.00051 19.8 0.9 5.6 6 0 0 6 6 6 3 C2H2-type zinc finger zf-met PF12874.2 ETO21723.1 - 0.001 19.1 29.8 0.2 11.9 0.2 5.5 5 0 0 5 5 5 3 Zinc-finger of C2H2 type C1_4 PF07975.7 ETO21723.1 - 0.032 14.2 33.2 0.71 9.9 2.3 4.5 2 1 2 4 4 4 0 TFIIH C1-like domain Zn-ribbon_8 PF09723.5 ETO21723.1 - 0.047 13.6 19.6 5.7 6.9 0.9 4.8 4 0 0 4 4 4 0 Zinc ribbon domain zf-BED PF02892.10 ETO21723.1 - 0.6 9.9 29.7 0.37 10.5 0.2 4.8 3 1 2 5 5 5 0 BED zinc finger zf-LYAR PF08790.6 ETO21723.1 - 0.99 9.1 26.0 0.12 12.1 1.2 5.4 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger PyrI_C PF02748.10 ETO21723.1 - 2.7 7.5 17.9 0.21 11.0 0.4 4.1 3 1 1 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-Di19 PF05605.7 ETO21723.1 - 4.2 7.5 29.0 0.68 10.1 3.8 3.9 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 ETO21723.1 - 7.2 6.7 36.3 19 5.4 10.4 4.7 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) RRM_1 PF00076.17 ETO21724.1 - 3.7e-13 48.9 0.1 1.4e-12 47.0 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO21724.1 - 4e-09 36.3 0.0 7.5e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO21724.1 - 0.00055 19.7 0.3 0.28 11.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO21725.1 - 3.7e-05 23.2 0.0 0.00013 21.5 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO21725.1 - 0.00089 19.1 0.0 0.0023 17.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) EI24 PF07264.6 ETO21725.1 - 1.8 7.9 13.4 1.8 7.9 8.3 1.7 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF4131 PF13567.1 ETO21725.1 - 2.3 7.6 7.1 9.4 5.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Mito_carr PF00153.22 ETO21726.1 - 0.001 18.7 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial carrier protein RHD PF00554.17 ETO21726.1 - 0.096 12.4 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Rel homology domain (RHD) Laps PF10169.4 ETO21727.1 - 0.11 12.7 9.1 0.62 10.2 6.4 2.0 1 1 1 2 2 2 0 Learning-associated protein ARPC4 PF05856.7 ETO21729.1 - 2.6e-69 231.9 3.9 2.9e-69 231.7 2.7 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) P34-Arc PF04045.9 ETO21729.1 - 0.024 13.9 0.4 0.23 10.7 0.1 2.1 1 1 1 2 2 2 0 Arp2/3 complex, 34 kD subunit p34-Arc Anticodon_1 PF08264.8 ETO21730.1 - 0.0076 16.0 0.4 0.021 14.5 0.1 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA DUF365 PF04033.7 ETO21730.1 - 0.087 12.8 0.1 0.66 9.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF365) Bromodomain PF00439.20 ETO21732.1 - 4.9e-19 68.0 0.7 2.1e-18 65.9 0.3 2.1 2 0 0 2 2 2 1 Bromodomain DUF2457 PF10446.4 ETO21732.1 - 0.0033 16.2 29.5 0.0033 16.2 20.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) Nop14 PF04147.7 ETO21732.1 - 0.16 9.8 34.4 0.0027 15.7 15.1 2.2 2 0 0 2 2 2 0 Nop14-like family DUF605 PF04652.11 ETO21732.1 - 4.4 6.5 36.0 0.66 9.3 11.7 2.1 2 0 0 2 2 2 0 Vta1 like Nucleo_P87 PF07267.6 ETO21733.1 - 0.12 11.0 5.1 0.14 10.8 3.6 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Spore_coat_CotO PF14153.1 ETO21733.1 - 0.88 8.9 13.1 0.96 8.8 9.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Vfa1 PF08432.5 ETO21733.1 - 1.3 9.0 12.8 1.9 8.4 8.9 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RR_TM4-6 PF06459.7 ETO21733.1 - 1.6 8.5 13.3 1.9 8.3 9.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TMEM51 PF15345.1 ETO21733.1 - 2.1 7.9 6.5 2.8 7.5 4.5 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Peptidase_S64 PF08192.6 ETO21733.1 - 2.8 6.1 7.5 3.2 5.9 5.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF1510 PF07423.6 ETO21733.1 - 3.2 7.0 14.5 3.9 6.7 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF3381 PF11861.3 ETO21733.1 - 4.5 6.7 13.1 7.1 6.1 9.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) CDC45 PF02724.9 ETO21733.1 - 6.2 4.7 10.8 6.8 4.5 7.5 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.7 ETO21733.1 - 6.4 5.4 6.3 7.3 5.2 4.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SpoIIIAH PF12685.2 ETO21733.1 - 6.6 6.1 10.3 8.7 5.7 7.2 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein DDHD PF02862.12 ETO21733.1 - 8.3 6.1 10.0 10 5.8 6.9 1.2 1 0 0 1 1 1 0 DDHD domain Zip PF02535.17 ETO21733.1 - 9.8 5.0 7.7 11 4.9 5.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Pkinase PF00069.20 ETO21734.1 - 5.7e-21 74.8 4.8 6.2e-17 61.6 0.0 2.9 2 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO21734.1 - 2.5e-06 26.7 1.0 0.042 12.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase DUF2370 PF10176.4 ETO21734.1 - 0.011 15.1 2.7 0.016 14.5 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) SR-25 PF10500.4 ETO21734.1 - 0.019 14.4 1.2 0.019 14.4 0.9 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein IPK PF03770.11 ETO21734.1 - 0.023 14.3 0.0 0.023 14.3 0.0 1.9 2 0 0 2 2 2 0 Inositol polyphosphate kinase DDHD PF02862.12 ETO21734.1 - 0.13 12.0 3.3 3.3 7.4 0.2 2.0 2 0 0 2 2 2 0 DDHD domain RP-C_C PF11800.3 ETO21734.1 - 0.62 9.7 6.0 5.8 6.5 0.1 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region DUF912 PF06024.7 ETO21734.1 - 1.4 9.0 5.0 4.3 7.4 0.9 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) POX PF07526.6 ETO21734.1 - 4.5 7.4 10.3 2.8 8.1 0.5 2.2 2 0 0 2 2 2 0 Associated with HOX DUF663 PF04950.7 ETO21735.1 - 0.0016 17.4 0.2 0.0023 16.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF663) YqzM PF14141.1 ETO21736.1 - 0.0048 16.6 1.3 0.0048 16.6 0.9 2.2 3 0 0 3 3 3 1 YqzM-like protein DUF819 PF05684.7 ETO21736.1 - 0.09 11.5 0.2 0.1 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF819) Blt1 PF12754.2 ETO21736.1 - 0.1 12.1 0.7 0.14 11.6 0.5 1.2 1 0 0 1 1 1 0 Cell-cycle control medial ring component DUF260 PF03195.9 ETO21736.1 - 0.11 12.7 1.1 0.18 12.0 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF260 eIF3_p135 PF12807.2 ETO21738.1 - 0.023 14.6 0.2 0.034 14.1 0.2 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 UMPH-1 PF05822.7 ETO21739.1 - 2.9e-16 59.5 1.1 5.2e-16 58.6 0.7 1.4 1 1 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.2 ETO21739.1 - 0.00042 20.5 0.0 0.00067 19.8 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 ETO21739.1 - 0.017 15.3 0.0 0.023 14.8 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Nop52 PF05997.7 ETO21739.1 - 0.13 11.7 4.2 0.12 11.7 0.8 2.2 1 1 1 2 2 2 0 Nucleolar protein,Nop52 UMPH-1 PF05822.7 ETO21740.1 - 3.3e-14 52.8 0.1 3.8e-14 52.6 0.1 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) DUF460 PF04312.8 ETO21741.1 - 0.0065 15.9 0.4 2.5 7.5 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF460) Usp PF00582.21 ETO21741.1 - 0.1 12.7 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Universal stress protein family Aldedh PF00171.17 ETO21742.1 - 2.1e-05 23.0 0.1 2.5e-05 22.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3583 PF12126.3 ETO21742.1 - 0.014 14.5 0.2 0.014 14.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) DUF4160 PF13711.1 ETO21742.1 - 0.026 14.3 0.3 0.066 13.0 0.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4160) HSD3 PF15244.1 ETO21742.1 - 0.088 12.0 3.9 0.099 11.8 2.7 1.0 1 0 0 1 1 1 0 Hydroxy-steroid dehydrogenase ATP-cone PF03477.11 ETO21742.1 - 0.095 13.1 0.7 0.16 12.4 0.5 1.4 1 1 0 1 1 1 0 ATP cone domain PapB PF03333.8 ETO21742.1 - 0.19 11.5 0.9 1.6 8.5 0.6 2.1 1 1 0 1 1 1 0 Adhesin biosynthesis transcription regulatory protein FlaG PF03646.10 ETO21742.1 - 0.33 11.1 3.0 0.41 10.8 2.1 1.3 1 0 0 1 1 1 0 FlaG protein DUF334 PF03904.8 ETO21742.1 - 0.38 10.0 4.2 0.43 9.8 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) FKBP_N PF01346.13 ETO21742.1 - 0.57 10.2 3.7 3 7.9 2.6 1.9 1 1 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase ABC_tran_2 PF12848.2 ETO21742.1 - 1 9.2 6.0 2.3 8.1 3.7 1.8 1 1 1 2 2 2 0 ABC transporter DUF2361 PF10153.4 ETO21742.1 - 5 7.3 8.6 0.88 9.7 2.5 1.8 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2361) WD40 PF00400.27 ETO21743.1 - 0.00041 20.1 4.7 3.6 7.6 0.1 5.1 5 2 0 5 5 5 2 WD domain, G-beta repeat DUF912 PF06024.7 ETO21743.1 - 5.5 7.1 7.3 0.49 10.4 1.5 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FliD_N PF02465.13 ETO21744.1 - 0.0097 16.2 9.5 0.017 15.4 6.6 1.3 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 N-terminus MSP1_C PF07462.6 ETO21744.1 - 0.05 11.9 1.7 0.065 11.6 1.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus HNF_C PF09354.5 ETO21744.1 - 0.15 13.1 4.7 0.15 13.2 1.8 2.1 2 0 0 2 2 2 0 HNF3 C-terminal domain YebO PF13974.1 ETO21745.1 - 0.1 12.3 0.4 0.1 12.3 0.3 2.2 2 1 0 2 2 2 0 YebO-like protein Apc15p PF05841.6 ETO21745.1 - 1.5 9.5 14.0 2 9.1 9.7 1.2 1 0 0 1 1 1 0 Apc15p protein DUF3537 PF12056.3 ETO21745.1 - 2.8 6.5 5.3 3.5 6.2 3.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) DUF1754 PF08555.5 ETO21745.1 - 2.8 8.5 11.3 0.26 11.9 4.3 1.8 1 1 1 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Menin PF05053.8 ETO21745.1 - 8.8 4.3 8.3 8.4 4.4 5.7 1.1 1 0 0 1 1 1 0 Menin PQQ_2 PF13360.1 ETO21749.1 - 0.00018 21.0 0.0 0.0027 17.2 0.0 2.0 1 1 1 2 2 2 2 PQQ-like domain Coatomer_WDAD PF04053.9 ETO21749.1 - 0.0055 15.5 0.3 1.1 7.9 0.0 3.0 1 1 2 3 3 3 2 Coatomer WD associated region Clathrin_propel PF01394.15 ETO21749.1 - 0.062 13.6 0.0 0.19 12.0 0.0 1.9 1 0 0 1 1 1 0 Clathrin propeller repeat CUE PF02845.11 ETO21750.1 - 0.00081 18.8 0.3 0.0019 17.6 0.2 1.7 1 0 0 1 1 1 1 CUE domain UBA_4 PF14555.1 ETO21750.1 - 0.021 14.3 0.1 0.038 13.5 0.1 1.4 1 0 0 1 1 1 0 UBA-like domain UBA PF00627.26 ETO21750.1 - 0.059 13.2 0.6 0.13 12.1 0.4 1.6 1 0 0 1 1 1 0 UBA/TS-N domain IPP-2 PF04979.9 ETO21750.1 - 0.15 12.2 5.7 0.31 11.2 3.9 1.5 1 0 0 1 1 1 0 Protein phosphatase inhibitor 2 (IPP-2) DUF3533 PF12051.3 ETO21751.1 - 0.025 13.3 0.2 0.036 12.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Cation_efflux PF01545.16 ETO21751.1 - 0.041 12.9 0.1 0.046 12.7 0.1 1.1 1 0 0 1 1 1 0 Cation efflux family DUF716 PF04819.7 ETO21751.1 - 0.043 13.2 0.2 0.043 13.2 0.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF716) Zip PF02535.17 ETO21751.1 - 0.15 11.0 1.4 0.21 10.5 1.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CBS PF00571.23 ETO21752.1 - 3.2e-07 30.0 0.0 7e-07 28.9 0.0 1.6 1 1 0 1 1 1 1 CBS domain WD40 PF00400.27 ETO21753.1 - 1.9e-67 220.9 27.1 1.7e-13 49.8 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO21753.1 - 3.7e-08 33.3 0.2 0.014 15.0 0.0 3.4 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO21753.1 - 5e-05 21.6 10.7 0.46 8.5 0.0 5.1 1 1 4 5 5 5 5 Nucleoporin Nup120/160 PD40 PF07676.7 ETO21753.1 - 0.0026 17.3 1.9 2.8 7.7 0.1 3.8 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO21753.1 - 0.024 14.9 2.5 15 5.9 0.2 4.1 2 2 3 5 5 5 0 Resistin Me-amine-dh_H PF06433.6 ETO21753.1 - 0.037 12.6 0.0 0.1 11.2 0.0 1.9 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) Ricin_B_lectin PF00652.17 ETO21753.1 - 0.11 12.4 2.8 0.67 9.9 0.1 2.8 1 1 2 3 3 3 0 Ricin-type beta-trefoil lectin domain Syntaxin_2 PF14523.1 ETO21754.1 - 2.5e-05 24.2 9.3 3.5e-05 23.7 6.5 1.2 1 0 0 1 1 1 1 Syntaxin-like protein zf-C4H2 PF10146.4 ETO21754.1 - 0.0049 16.9 1.8 0.0074 16.3 1.3 1.3 1 1 0 1 1 1 1 Zinc finger-containing protein XH PF03469.9 ETO21754.1 - 0.05 13.2 2.0 0.09 12.4 0.8 1.8 1 1 1 2 2 2 0 XH domain V_ATPase_I PF01496.14 ETO21754.1 - 0.061 11.1 3.8 0.071 10.9 2.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CDC37_N PF03234.9 ETO21754.1 - 1.3 9.2 7.5 1 9.6 4.0 1.7 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding TcdB_N PF12918.2 ETO21754.1 - 8.6 6.5 10.0 1.1 9.4 0.1 3.1 2 2 1 3 3 3 0 TcdB toxin N-terminal helical domain WD40 PF00400.27 ETO21756.1 - 2.4e-72 236.4 23.3 3.4e-13 48.8 0.2 7.8 8 0 0 8 8 8 7 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO21756.1 - 1.7e-05 24.8 13.5 0.11 12.6 0.3 5.8 4 2 2 6 6 6 2 Kelch motif Kelch_1 PF01344.20 ETO21756.1 - 2.3e-05 23.8 7.4 0.77 9.3 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 ETO21756.1 - 0.00016 21.3 0.2 0.0079 15.9 0.1 3.8 4 0 0 4 4 4 1 Galactose oxidase, central domain PQQ_2 PF13360.1 ETO21756.1 - 0.007 15.8 0.2 0.13 11.7 0.7 2.6 2 1 0 2 2 2 1 PQQ-like domain Kelch_3 PF13415.1 ETO21756.1 - 0.012 15.8 0.3 0.5 10.5 0.0 3.5 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO21756.1 - 0.022 14.7 2.1 33 4.5 1.2 4.2 4 0 0 4 4 4 0 Kelch motif PLD_C PF12357.3 ETO21756.1 - 0.029 13.9 0.0 6.9 6.2 0.0 3.6 3 0 0 3 3 3 0 Phospholipase D C terminal Multi_Drug_Res PF00893.14 ETO21757.1 - 0.066 13.6 0.2 0.18 12.2 0.1 1.7 2 0 0 2 2 2 0 Small Multidrug Resistance protein SelB-wing_3 PF09107.6 ETO21757.1 - 0.08 12.3 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 Elongation factor SelB, winged helix CDC45 PF02724.9 ETO21759.1 - 0.56 8.1 6.6 0.81 7.6 4.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Tom22 PF04281.8 ETO21759.1 - 0.7 9.4 6.6 2.7 7.5 3.2 2.4 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 DUF373 PF04123.8 ETO21759.1 - 3.6 6.5 7.6 4.8 6.1 2.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF373) SBP_bac_11 PF13531.1 ETO21761.1 - 1.8e-06 27.7 0.0 3.1e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.1 ETO21761.1 - 0.093 12.4 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein WD40 PF00400.27 ETO21762.1 - 2.3e-11 43.0 0.9 6e-11 41.7 0.1 2.1 3 0 0 3 3 3 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO21762.1 - 0.13 10.4 0.0 0.13 10.3 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DUF3899 PF13038.1 ETO21763.1 - 4.4 7.5 4.5 47 4.2 2.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) RRM_5 PF13893.1 ETO21764.1 - 8.7e-08 31.8 0.1 1.6e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO21764.1 - 5.2e-07 29.1 0.0 1e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO21764.1 - 0.0024 17.8 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 ETO21765.1 - 0.0057 15.1 26.6 0.011 14.2 18.5 1.3 1 1 0 1 1 1 1 Microtubule-binding protein MIP-T3 MRAP PF15183.1 ETO21765.1 - 0.037 13.6 0.2 0.12 11.9 0.1 1.9 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family Vfa1 PF08432.5 ETO21765.1 - 0.31 11.0 26.6 1.7 8.6 2.5 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF966 PF06136.8 ETO21765.1 - 1.7 8.0 23.1 0.5 9.7 3.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF966) Ycf1 PF05758.7 ETO21765.1 - 3.1 5.4 25.6 0.22 9.2 1.4 2.0 1 1 1 2 2 2 0 Ycf1 Nop25 PF09805.4 ETO21765.1 - 4.1 7.4 26.7 0.71 9.9 2.1 2.1 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) RIP PF00161.14 ETO21767.1 - 0.014 14.5 0.2 0.31 10.1 0.0 2.4 2 0 0 2 2 2 0 Ribosome inactivating protein MIP-T3 PF10243.4 ETO21768.1 - 0.54 8.6 69.7 0.66 8.3 48.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PHD PF00628.24 ETO21770.1 - 1.7e-08 34.0 5.6 1.7e-08 34.0 3.9 4.1 4 0 0 4 4 4 1 PHD-finger zf-RING_2 PF13639.1 ETO21770.1 - 7.8e-06 25.6 0.4 7.8e-06 25.6 0.3 3.5 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 ETO21770.1 - 0.0004 19.9 1.2 0.0004 19.9 0.9 3.4 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO21770.1 - 0.00064 19.7 1.4 0.00064 19.7 1.0 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETO21770.1 - 0.0089 16.1 0.5 0.0089 16.1 0.4 3.6 3 0 0 3 3 3 1 RING-H2 zinc finger PHD_2 PF13831.1 ETO21770.1 - 0.012 14.8 1.8 0.012 14.8 1.3 3.2 3 0 0 3 3 3 0 PHD-finger DUF2244 PF10003.4 ETO21770.1 - 0.026 13.9 0.1 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) zf-C3HC4_4 PF15227.1 ETO21770.1 - 0.028 14.2 8.6 0.039 13.8 0.3 3.2 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 ETO21770.1 - 0.043 13.6 0.2 0.043 13.6 0.1 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger BAF1_ABF1 PF04684.8 ETO21771.1 - 1.5 7.6 17.8 2.6 6.7 12.3 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Myosin_TH1 PF06017.8 ETO21772.1 - 0.00065 19.0 10.8 0.0026 17.1 7.5 2.0 1 1 0 1 1 1 1 Myosin tail C2 PF00168.25 ETO21773.1 - 1.3e-07 31.3 0.1 2.6e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain Nop14 PF04147.7 ETO21773.1 - 0.00044 18.3 6.8 0.00053 18.0 4.7 1.1 1 0 0 1 1 1 1 Nop14-like family TRAP_alpha PF03896.11 ETO21773.1 - 0.0015 17.6 4.6 0.0022 17.0 3.2 1.2 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit SID-1_RNA_chan PF13965.1 ETO21773.1 - 0.012 13.8 1.5 0.017 13.3 1.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Daxx PF03344.10 ETO21773.1 - 0.012 14.1 11.4 0.016 13.7 7.9 1.2 1 0 0 1 1 1 0 Daxx Family DUF2151 PF10221.4 ETO21773.1 - 0.057 11.5 4.6 0.068 11.3 3.2 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator CDC45 PF02724.9 ETO21773.1 - 0.17 9.8 7.8 0.22 9.5 5.4 1.2 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.7 ETO21773.1 - 0.33 10.0 12.8 0.47 9.5 8.9 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Prothymosin PF03247.9 ETO21773.1 - 0.75 9.9 24.6 2.3 8.4 17.1 1.7 1 0 0 1 1 1 0 Prothymosin/parathymosin family DUF2890 PF11081.3 ETO21773.1 - 1.5 8.8 17.1 3.6 7.6 11.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Stn1 PF10451.4 ETO21773.1 - 2.1 7.1 6.7 1.7 7.3 2.4 2.0 2 0 0 2 2 2 0 Telomere regulation protein Stn1 DUF1980 PF09323.5 ETO21773.1 - 4.1 7.0 6.6 0.39 10.4 0.8 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) Nucleoplasmin PF03066.10 ETO21773.1 - 4.5 6.7 15.7 8.2 5.9 10.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin DUF3439 PF11921.3 ETO21774.1 - 0.12 12.1 6.5 0.21 11.3 4.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 ETO21774.1 - 0.87 7.4 9.4 1.3 6.9 6.5 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF843 PF05814.6 ETO21774.1 - 4.9 7.0 5.9 3 7.6 0.1 2.6 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) CDC45 PF02724.9 ETO21774.1 - 5.9 4.8 14.6 7.9 4.3 10.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4047 PF13256.1 ETO21775.1 - 0.17 11.8 4.5 0.68 9.9 3.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) DUF4201 PF13870.1 ETO21777.1 - 2.2e-33 115.1 32.2 2.2e-33 115.1 22.3 3.8 3 1 2 5 5 5 1 Domain of unknown function (DUF4201) Adhesin_P1 PF03257.8 ETO21777.1 - 0.13 12.6 4.2 0.095 13.0 1.1 2.0 1 1 1 2 2 2 0 Mycoplasma adhesin P1 RabGAP-TBC PF00566.13 ETO21778.1 - 2.4e-13 50.0 6.4 4.8e-13 49.0 4.0 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Menin PF05053.8 ETO21778.1 - 0.046 11.8 0.9 0.058 11.5 0.6 1.1 1 0 0 1 1 1 0 Menin DUF1151 PF06625.6 ETO21778.1 - 1.2 8.8 7.3 0.55 9.9 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) RabGAP-TBC PF00566.13 ETO21779.1 - 1.1e-11 44.5 2.1 1.1e-11 44.5 1.5 2.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Tetraspannin PF00335.15 ETO21779.1 - 0.0035 16.6 3.3 0.0084 15.4 2.3 1.6 1 0 0 1 1 1 1 Tetraspanin family RP-C_C PF11800.3 ETO21779.1 - 2.3 7.8 4.4 3.8 7.1 3.0 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Transposase_mut PF00872.13 ETO21780.1 - 0.15 10.6 0.2 0.19 10.2 0.1 1.1 1 0 0 1 1 1 0 Transposase, Mutator family Kelch_1 PF01344.20 ETO21781.1 - 0.00014 21.2 0.5 0.00042 19.7 0.3 1.8 1 0 0 1 1 1 1 Kelch motif Kelch_6 PF13964.1 ETO21781.1 - 0.00047 20.2 1.2 0.0097 16.0 0.1 2.7 1 1 1 2 2 2 1 Kelch motif Kelch_4 PF13418.1 ETO21781.1 - 0.017 14.9 0.0 0.017 14.9 0.0 2.5 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO21781.1 - 0.099 12.4 1.2 0.96 9.3 0.1 2.6 2 0 0 2 2 2 0 Kelch motif DUF2457 PF10446.4 ETO21782.1 - 0.015 14.0 16.9 0.02 13.6 11.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Trypan_PARP PF05887.6 ETO21782.1 - 2.2 8.1 6.4 3.2 7.5 4.4 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DARPP-32 PF05395.7 ETO21782.1 - 2.8 8.0 14.5 1.8 8.7 8.8 1.6 1 1 1 2 2 2 0 Protein phosphatase inhibitor 1/DARPP-32 CDC45 PF02724.9 ETO21782.1 - 7.6 4.4 9.1 6.6 4.6 6.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF148 PF02520.12 ETO21783.1 - 0.043 13.6 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF148 DUF3760 PF12586.3 ETO21784.1 - 0.13 12.0 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) FtsX PF02687.16 ETO21785.1 - 3.1e-11 43.1 1.6 6.7e-11 42.0 1.1 1.6 1 0 0 1 1 1 1 FtsX-like permease family Kringle PF00051.13 ETO21785.1 - 9.6e-05 22.4 0.6 0.00026 21.0 0.4 1.8 1 0 0 1 1 1 1 Kringle domain Gal_Lectin PF02140.13 ETO21785.1 - 0.00022 21.4 1.6 0.00048 20.3 1.1 1.6 1 0 0 1 1 1 1 Galactose binding lectin domain DUF3464 PF11947.3 ETO21785.1 - 0.096 12.1 0.3 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) Nop14 PF04147.7 ETO21786.1 - 0.00074 17.5 15.7 0.00074 17.5 10.9 2.1 2 0 0 2 2 2 1 Nop14-like family Spore_coat_CotO PF14153.1 ETO21786.1 - 0.14 11.6 24.9 0.34 10.3 8.3 2.3 2 0 0 2 2 2 0 Spore coat protein CotO DUF4045 PF13254.1 ETO21786.1 - 0.58 9.3 25.7 1.4 8.1 3.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) Zip PF02535.17 ETO21786.1 - 1.1 8.2 17.6 2.2 7.1 5.5 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter Daxx PF03344.10 ETO21786.1 - 1.7 7.0 37.0 0.026 13.0 10.2 2.1 2 0 0 2 2 2 0 Daxx Family FLO_LFY PF01698.11 ETO21786.1 - 3.1 6.5 27.2 0.43 9.3 5.8 2.4 2 0 0 2 2 2 0 Floricaula / Leafy protein CDC45 PF02724.9 ETO21786.1 - 3.7 5.4 29.1 0.027 12.5 7.7 2.1 2 0 0 2 2 2 0 CDC45-like protein SprA-related PF12118.3 ETO21786.1 - 4.6 6.4 37.3 4.1 6.6 10.1 2.2 2 0 0 2 2 2 0 SprA-related family DUF1510 PF07423.6 ETO21786.1 - 5.8 6.2 51.0 2 7.7 17.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) MIP-T3 PF10243.4 ETO21786.1 - 6.8 5.0 40.4 0.073 11.5 15.4 2.2 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Utp14 PF04615.8 ETO21786.1 - 7 4.6 42.3 1.2 7.1 11.6 2.1 2 0 0 2 2 2 0 Utp14 protein Alpha_kinase PF02816.13 ETO21787.1 - 3.1e-50 170.4 0.7 1.7e-48 164.8 0.5 2.1 1 1 0 1 1 1 1 Alpha-kinase family RRM_6 PF14259.1 ETO21788.1 - 0.0012 18.7 0.0 0.0055 16.6 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 ETO21788.1 - 0.024 13.1 23.7 0.031 12.7 16.4 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RRM_1 PF00076.17 ETO21788.1 - 0.031 13.9 0.0 0.82 9.3 0.0 2.4 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Macoilin PF09726.4 ETO21788.1 - 0.088 11.0 14.9 0.11 10.6 10.3 1.2 1 0 0 1 1 1 0 Transmembrane protein Rib_recp_KP_reg PF05104.7 ETO21788.1 - 9.8 6.6 20.1 23 5.4 13.9 1.6 1 1 0 1 1 1 0 Ribosome receptor lysine/proline rich region RRM_5 PF13893.1 ETO21789.1 - 7.9e-07 28.8 0.1 1.7e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO21789.1 - 6.2e-06 25.7 0.1 3.3e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO21789.1 - 0.041 13.8 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 ETO21790.1 - 1.4e-60 204.6 0.0 2.3e-60 203.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO21790.1 - 8.1e-28 97.1 0.0 1.3e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO21790.1 - 9.5e-05 21.4 0.0 0.00017 20.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETO21790.1 - 0.029 13.4 0.0 0.073 12.1 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1900 PF08954.6 ETO21791.1 - 4.2e-50 168.8 0.0 3.8e-49 165.6 0.0 2.2 2 1 1 3 3 3 1 Domain of unknown function (DUF1900) WD40 PF00400.27 ETO21791.1 - 7e-17 60.6 0.9 4.8e-09 35.7 0.0 2.8 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO21791.1 - 0.00057 18.1 0.0 0.00096 17.4 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 DivIC PF04977.10 ETO21791.1 - 0.0011 18.3 0.2 0.0021 17.5 0.2 1.4 1 0 0 1 1 1 1 Septum formation initiator bZIP_2 PF07716.10 ETO21791.1 - 0.044 13.6 2.3 0.086 12.6 1.6 1.4 1 0 0 1 1 1 0 Basic region leucine zipper DUF1192 PF06698.6 ETO21791.1 - 0.05 13.4 0.3 0.097 12.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) IFP_35_N PF07334.8 ETO21791.1 - 0.052 13.5 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF1283 PF06932.6 ETO21792.1 - 0.045 13.7 4.0 3.3 7.8 0.5 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1283) DUF883 PF05957.8 ETO21792.1 - 6.8 7.1 8.8 29 5.1 0.3 3.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) RhoGEF PF00621.15 ETO21795.1 - 6.1e-20 71.8 0.0 1e-19 71.1 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain DUF4131 PF13567.1 ETO21796.1 - 0.18 11.1 1.5 0.37 10.1 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) FA_desaturase PF00487.19 ETO21797.1 - 0.0053 16.2 1.3 0.0098 15.3 0.9 1.4 1 0 0 1 1 1 1 Fatty acid desaturase URO-D PF01208.12 ETO21799.1 - 8.6e-104 347.1 0.0 9.9e-104 346.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) VPS9 PF02204.13 ETO21800.1 - 1.3e-08 34.7 0.7 3e-08 33.5 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain DUF869 PF05911.6 ETO21800.1 - 0.0038 15.5 12.2 0.0065 14.7 8.4 1.3 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) CAP_N PF01213.14 ETO21801.1 - 0.018 14.3 2.2 0.022 14.0 1.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF4136 PF13590.1 ETO21801.1 - 0.031 14.3 0.3 0.032 14.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4136) TEX19 PF15553.1 ETO21801.1 - 0.069 13.0 1.4 0.078 12.8 0.9 1.2 1 0 0 1 1 1 0 Testis-expressed protein 19 DUF572 PF04502.8 ETO21801.1 - 0.12 11.5 7.9 0.14 11.3 5.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Mito_fiss_reg PF05308.6 ETO21801.1 - 0.54 9.5 11.4 0.24 10.7 6.5 1.4 1 1 0 1 1 1 0 Mitochondrial fission regulator TFIIF_alpha PF05793.7 ETO21801.1 - 1.5 7.1 17.0 1.7 6.8 11.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Orbi_VP6 PF01516.11 ETO21801.1 - 1.6 7.7 11.1 2 7.4 7.7 1.1 1 0 0 1 1 1 0 Orbivirus helicase VP6 Topoisom_I_N PF02919.10 ETO21801.1 - 1.7 7.8 6.3 2.2 7.5 4.4 1.2 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Mif2_N PF15624.1 ETO21801.1 - 3.4 8.2 10.8 5.6 7.5 7.5 1.5 1 1 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal DUF605 PF04652.11 ETO21801.1 - 3.8 6.8 13.5 4.6 6.5 9.3 1.0 1 0 0 1 1 1 0 Vta1 like Lin-8 PF03353.10 ETO21801.1 - 4.6 6.4 9.9 5.7 6.1 6.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Daxx PF03344.10 ETO21801.1 - 6.4 5.1 13.6 7.2 4.9 9.4 1.0 1 0 0 1 1 1 0 Daxx Family Pkinase PF00069.20 ETO21804.1 - 3e-16 59.3 0.0 3.8e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO21804.1 - 0.0023 17.0 0.0 0.003 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ACP53EA PF06313.6 ETO21804.1 - 0.13 12.2 0.1 4.7 7.2 0.0 2.4 1 1 0 2 2 2 0 Drosophila ACP53EA protein PH PF00169.24 ETO21805.1 - 2.2e-08 34.2 5.2 2.9e-06 27.4 0.2 2.5 2 1 0 2 2 2 2 PH domain PH_11 PF15413.1 ETO21805.1 - 2.6e-05 24.4 1.1 0.0018 18.4 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain CDC45 PF02724.9 ETO21805.1 - 0.0056 14.7 5.4 0.0064 14.5 3.7 1.2 1 0 0 1 1 1 1 CDC45-like protein Ycf1 PF05758.7 ETO21805.1 - 0.019 12.7 1.3 0.016 12.9 0.9 1.1 1 0 0 1 1 1 0 Ycf1 TFIIF_alpha PF05793.7 ETO21805.1 - 0.94 7.7 20.6 1.2 7.3 14.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ELL PF10390.4 ETO21807.1 - 0.016 14.4 0.8 0.016 14.4 0.6 2.2 2 2 0 2 2 2 0 RNA polymerase II elongation factor ELL MucB_RseB PF03888.9 ETO21807.1 - 0.026 13.5 0.8 0.051 12.6 0.6 1.4 1 0 0 1 1 1 0 MucB/RseB family DUF4484 PF14831.1 ETO21807.1 - 0.14 12.2 6.3 2.6 8.1 1.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) CENP-B_dimeris PF09026.5 ETO21807.1 - 0.48 10.6 5.0 1.2 9.4 3.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Merozoite_SPAM PF07133.6 ETO21808.1 - 0.00091 19.1 14.8 0.00091 19.1 10.2 3.2 2 1 0 2 2 2 1 Merozoite surface protein (SPAM) tRNA-synt_1 PF00133.17 ETO21809.1 - 1.5e-18 66.2 1.9 8.1e-16 57.1 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 ETO21809.1 - 0.0016 17.1 0.1 0.0016 17.1 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (M) Cpn60_TCP1 PF00118.19 ETO21811.1 - 2.1e-149 498.2 6.0 2.4e-149 498.0 4.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HEAT PF02985.17 ETO21813.1 - 0.00016 21.4 0.4 0.015 15.3 0.0 3.5 3 0 0 3 3 3 1 HEAT repeat FCP1_C PF09309.5 ETO21816.1 - 0.13 11.5 5.5 0.16 11.2 3.8 1.1 1 0 0 1 1 1 0 FCP1, C-terminal Daxx PF03344.10 ETO21817.1 - 0.00043 18.9 30.4 0.00043 18.9 21.0 2.0 2 0 0 2 2 2 1 Daxx Family CENP-T PF15511.1 ETO21817.1 - 0.0014 17.9 15.4 0.0014 17.9 10.7 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T SprA-related PF12118.3 ETO21817.1 - 0.11 11.7 26.0 0.011 15.1 11.0 2.2 2 0 0 2 2 2 0 SprA-related family SAPS PF04499.10 ETO21817.1 - 0.42 9.2 17.0 0.16 10.6 8.9 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Astro_capsid PF03115.9 ETO21817.1 - 2.3 6.3 14.7 5.1 5.2 10.2 1.6 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Nop14 PF04147.7 ETO21817.1 - 2.4 5.9 47.2 0.0056 14.6 24.0 2.1 2 0 0 2 2 2 0 Nop14-like family Sporozoite_P67 PF05642.6 ETO21817.1 - 8.2 4.1 15.3 16 3.1 10.6 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SpecificRecomb PF10136.4 ETO21819.1 - 0.0036 15.4 0.0 0.0044 15.1 0.0 1.1 1 0 0 1 1 1 1 Site-specific recombinase Protocadherin PF08374.6 ETO21820.1 - 0.8 9.2 7.3 0.23 11.0 0.6 2.1 2 0 0 2 2 2 0 Protocadherin Utp14 PF04615.8 ETO21821.1 - 8.8 4.3 44.0 12 3.8 30.5 1.1 1 0 0 1 1 1 0 Utp14 protein Peptidase_M15_3 PF08291.6 ETO21822.1 - 5.6e-27 93.7 0.0 6.9e-16 58.0 0.0 2.6 2 0 0 2 2 2 2 Peptidase M15 Peptidase_M15_2 PF05951.8 ETO21822.1 - 0.00051 19.5 0.1 0.56 9.6 0.0 2.5 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF882) DUF1180 PF06679.7 ETO21822.1 - 0.0072 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) DUF912 PF06024.7 ETO21822.1 - 0.011 15.8 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) KilA-N PF04383.8 ETO21822.1 - 0.011 15.3 1.4 0.19 11.3 0.1 2.9 2 1 0 2 2 2 0 KilA-N domain DUF4448 PF14610.1 ETO21822.1 - 0.015 14.7 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) CD34_antigen PF06365.7 ETO21822.1 - 0.046 13.3 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family TMEM154 PF15102.1 ETO21822.1 - 0.06 13.0 0.2 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 TMEM154 protein family DAG1 PF05454.6 ETO21822.1 - 0.086 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Peptidase_C62 PF12380.3 ETO21823.1 - 0.0055 15.5 0.0 0.0078 15.0 0.0 1.2 1 0 0 1 1 1 1 Gill-associated viral 3C-like peptidase Tubulin PF00091.20 ETO21824.1 - 4.3e-56 190.1 0.0 2.9e-55 187.4 0.0 1.9 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO21824.1 - 4.2e-11 42.9 0.0 7e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Lipase_3 PF01764.20 ETO21824.1 - 0.0026 17.3 0.0 0.0052 16.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Actin PF00022.14 ETO21826.1 - 2.1e-123 411.6 0.0 2.4e-123 411.4 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 ETO21826.1 - 0.029 12.9 0.2 0.09 11.3 0.2 1.7 1 1 0 1 1 1 0 MreB/Mbl protein DUF1942 PF09167.6 ETO21827.1 - 0.1 12.3 0.8 0.18 11.5 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1942) DUF3840 PF12944.2 ETO21827.1 - 0.16 11.7 2.2 1.4 8.8 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3840) cNMP_binding PF00027.24 ETO21829.1 - 1.3e-06 28.1 0.0 2.8e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Orbi_VP5 PF00901.12 ETO21829.1 - 0.0065 14.7 0.2 0.024 12.8 0.0 1.8 2 0 0 2 2 2 1 Orbivirus outer capsid protein VP5 HPD PF05044.7 ETO21830.1 - 0.023 14.3 0.3 0.027 14.1 0.2 1.4 1 1 0 1 1 1 0 Homeo-prospero domain PqiA PF04403.8 ETO21831.1 - 9.9e-06 25.2 9.3 1.1e-05 25.1 5.6 1.7 2 1 0 2 2 2 1 Paraquat-inducible protein A DUF4233 PF14017.1 ETO21831.1 - 0.64 9.9 7.9 0.4 10.6 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4233) Ish1 PF10281.4 ETO21833.1 - 0.085 12.9 1.3 0.6 10.2 0.1 2.6 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein D123 PF07065.9 ETO21834.1 - 2.7e-11 43.0 0.8 3.1e-11 42.9 0.5 1.2 1 0 0 1 1 1 1 D123 DUF4343 PF14243.1 ETO21834.1 - 0.026 14.3 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4343) Glyco_hydro_47 PF01532.15 ETO21835.1 - 2.8e-26 92.1 0.2 3.6e-26 91.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 zf-CCCH PF00642.19 ETO21837.1 - 6.5e-09 35.2 17.1 1.2e-07 31.2 2.7 3.1 2 1 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 ETO21837.1 - 0.0012 18.8 7.3 0.0076 16.2 0.6 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type CLASP_N PF12348.3 ETO21838.1 - 1.7e-08 34.0 0.1 2.9e-08 33.3 0.1 1.3 1 0 0 1 1 1 1 CLASP N terminal Vac14_Fab1_bd PF12755.2 ETO21838.1 - 0.032 14.6 0.1 0.37 11.2 0.0 2.5 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Snf7 PF03357.16 ETO21839.1 - 1.3e-14 54.0 9.8 3e-14 52.7 6.8 1.6 1 0 0 1 1 1 1 Snf7 DUF3567 PF12091.3 ETO21839.1 - 0.0029 17.5 0.9 0.06 13.3 0.1 3.0 1 1 2 3 3 3 1 Protein of unknown function (DUF3567) DUF1957 PF09210.6 ETO21839.1 - 0.057 13.4 0.8 0.21 11.6 0.6 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1957) Nop25 PF09805.4 ETO21840.1 - 2.6 8.1 16.5 0.89 9.6 5.7 2.6 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) PID PF00640.18 ETO21841.1 - 0.066 13.1 1.5 0.096 12.6 1.1 1.3 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) DUF1939 PF09154.5 ETO21841.1 - 0.17 11.8 4.1 0.71 9.8 2.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1939) Pkinase PF00069.20 ETO21842.1 - 3.8e-62 209.8 0.0 4.4e-62 209.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO21842.1 - 8.4e-35 120.0 0.0 1.1e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO21842.1 - 9.5e-05 21.4 0.0 0.00027 20.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 ETO21842.1 - 0.0034 16.4 0.0 0.0057 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 ETO21842.1 - 0.0067 15.2 2.5 0.011 14.5 1.8 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.4 ETO21842.1 - 0.0069 15.7 0.1 0.01 15.1 0.1 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL TMEM173 PF15009.1 ETO21845.1 - 0.045 12.5 2.7 0.044 12.5 1.9 1.1 1 0 0 1 1 1 0 Transmembrane protein 173 MarC PF01914.12 ETO21845.1 - 0.37 9.8 5.9 0.41 9.7 4.1 1.2 1 1 0 1 1 1 0 MarC family integral membrane protein TMEMspv1-c74-12 PF11044.3 ETO21845.1 - 4.9 6.7 5.0 0.7 9.4 0.6 1.7 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF924 PF06041.6 ETO21846.1 - 4.2e-45 153.8 0.1 5.3e-45 153.4 0.1 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) TB2_DP1_HVA22 PF03134.14 ETO21847.1 - 5.7e-21 74.0 15.6 2.7e-12 46.2 0.3 2.8 3 0 0 3 3 3 2 TB2/DP1, HVA22 family PSII_BNR PF14870.1 ETO21849.1 - 0.00043 19.3 2.6 0.24 10.3 0.2 2.4 1 1 1 2 2 2 2 Photosynthesis system II assembly factor YCF48 BNR PF02012.15 ETO21849.1 - 0.0053 16.3 13.7 0.87 9.6 0.4 3.9 3 0 0 3 3 3 3 BNR/Asp-box repeat PITH PF06201.8 ETO21850.1 - 5e-26 91.2 3.0 1.3e-25 89.9 2.1 1.8 1 1 0 1 1 1 1 PITH domain Na_trans_assoc PF06512.8 ETO21851.1 - 0.02 14.8 9.2 0.025 14.5 6.4 1.0 1 0 0 1 1 1 0 Sodium ion transport-associated Peptidase_S64 PF08192.6 ETO21851.1 - 0.032 12.6 8.7 0.039 12.2 6.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 TATR PF03430.8 ETO21851.1 - 0.092 11.3 6.7 0.11 11.1 4.6 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Pox_P4B PF03292.9 ETO21851.1 - 0.23 9.3 4.8 0.27 9.1 3.3 1.0 1 0 0 1 1 1 0 Poxvirus P4B major core protein Presenilin PF01080.12 ETO21851.1 - 0.33 9.7 7.8 0.41 9.4 5.4 1.1 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.1 ETO21851.1 - 0.47 10.1 8.5 0.63 9.7 5.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Eapp_C PF10238.4 ETO21851.1 - 0.47 10.3 6.8 0.69 9.8 4.7 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein F-protein PF00469.15 ETO21851.1 - 0.77 9.0 8.0 1.3 8.3 5.5 1.3 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef RRF PF01765.14 ETO21851.1 - 0.9 8.9 8.3 1.1 8.6 5.3 1.5 1 1 0 1 1 1 0 Ribosome recycling factor DDHD PF02862.12 ETO21851.1 - 2 8.1 10.9 2.5 7.8 7.5 1.2 1 0 0 1 1 1 0 DDHD domain ROK PF00480.15 ETO21852.1 - 0.11 12.2 6.2 0.12 12.1 3.5 1.5 2 0 0 2 2 2 0 ROK family QueC PF06508.8 ETO21852.1 - 0.69 9.1 6.8 0.2 10.9 0.1 2.3 1 1 1 2 2 2 0 Queuosine biosynthesis protein QueC Med15 PF09606.5 ETO21852.1 - 1.6 6.7 65.5 2.6 6.1 45.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 ETO21852.1 - 4.6 5.3 48.6 5.7 5.0 33.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Arc_PepC_II PF06847.6 ETO21855.1 - 2.5 8.5 7.4 3.9 7.9 0.4 2.5 1 1 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II La PF05383.12 ETO21857.1 - 1e-19 70.0 0.2 1.8e-19 69.3 0.1 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 ETO21857.1 - 0.00078 19.0 0.0 0.0088 15.6 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 ETO21857.1 - 0.0041 15.6 32.3 0.0062 15.0 22.4 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF605 PF04652.11 ETO21857.1 - 0.0054 16.1 26.0 0.0069 15.8 18.0 1.1 1 0 0 1 1 1 1 Vta1 like BUD22 PF09073.5 ETO21857.1 - 0.073 12.1 34.8 0.14 11.1 24.1 1.4 1 0 0 1 1 1 0 BUD22 DMAP1 PF05499.7 ETO21857.1 - 2.5 7.6 13.6 0.55 9.7 0.1 2.4 2 0 0 2 2 2 0 DNA methyltransferase 1-associated protein 1 (DMAP1) SAM_2 PF07647.12 ETO21858.1 - 6.9e-08 32.2 0.1 1.3e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO21858.1 - 2.9e-06 27.3 0.0 6.2e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) WD40 PF00400.27 ETO21859.1 - 5.7e-54 178.1 20.4 6.8e-12 44.7 0.4 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO21859.1 - 9.9e-12 43.7 11.4 0.00023 19.4 0.2 4.9 2 2 2 5 5 5 5 Nucleoporin Nup120/160 ParBc_2 PF08857.6 ETO21859.1 - 0.067 13.0 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Putative ParB-like nuclease Kelch_6 PF13964.1 ETO21859.1 - 0.077 13.2 5.1 6.6 7.0 0.1 3.9 4 0 0 4 4 4 0 Kelch motif PH PF00169.24 ETO21860.1 - 1.2e-11 44.7 0.9 3.4e-11 43.2 0.6 1.9 1 0 0 1 1 1 1 PH domain PH_3 PF14593.1 ETO21860.1 - 7.3e-10 38.6 0.5 1.8e-09 37.3 0.4 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 ETO21860.1 - 0.00076 19.7 3.9 0.041 14.1 2.7 2.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 ETO21860.1 - 0.006 16.6 0.6 0.014 15.4 0.4 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain FAM176 PF14851.1 ETO21860.1 - 4.4 6.9 8.8 0.41 10.3 0.0 2.9 3 0 0 3 3 3 0 FAM176 family Tetraspannin PF00335.15 ETO21861.1 - 0.006 15.8 1.2 0.0071 15.6 0.9 1.1 1 0 0 1 1 1 1 Tetraspanin family PIH1 PF08190.7 ETO21861.1 - 0.04 13.3 0.1 0.049 13.0 0.0 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 zf-DHHC PF01529.15 ETO21861.1 - 0.12 11.7 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Sigma_reg_N PF13800.1 ETO21861.1 - 0.19 11.7 4.4 0.3 11.1 3.1 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DSPc PF00782.15 ETO21862.1 - 6.4e-25 87.2 0.1 9.4e-25 86.7 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain zf-RanBP PF00641.13 ETO21862.1 - 4.4e-06 25.7 5.0 9.5e-06 24.6 3.4 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Init_tRNA_PT PF04179.7 ETO21862.1 - 6.5e-06 25.2 0.1 8.1e-06 24.9 0.1 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase PF00102.22 ETO21862.1 - 2.8e-05 23.5 0.0 4.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 ETO21862.1 - 0.0027 17.1 0.1 0.0042 16.4 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DZR PF12773.2 ETO21862.1 - 0.47 10.3 4.3 0.34 10.7 1.4 1.9 2 0 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.1 ETO21862.1 - 1 8.6 4.1 0.36 10.1 0.8 1.9 2 0 0 2 2 2 0 zinc-ribbon domain Ribonuclease_3 PF00636.21 ETO21864.1 - 3.6e-12 46.7 0.0 9.3e-12 45.4 0.0 1.7 2 0 0 2 2 2 1 Ribonuclease III domain WD40 PF00400.27 ETO21865.1 - 4.2e-61 200.8 34.5 2.4e-13 49.3 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO21865.1 - 1.3e-09 36.8 13.3 0.0024 16.1 1.1 5.5 1 1 5 6 6 6 4 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO21865.1 - 1e-05 25.3 1.2 0.18 11.4 0.0 4.0 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Neuregulin PF02158.10 ETO21865.1 - 0.0011 17.8 0.1 0.0019 17.0 0.1 1.3 1 0 0 1 1 1 1 Neuregulin family 2OG-FeII_Oxy_4 PF13661.1 ETO21867.1 - 0.022 14.3 0.8 0.072 12.7 0.5 1.8 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 ETO21867.1 - 0.061 13.8 0.1 0.1 13.0 0.0 1.4 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily zf-met PF12874.2 ETO21868.1 - 0.022 14.9 0.5 0.068 13.4 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Rep_fac-A_C PF08646.5 ETO21868.1 - 0.035 13.8 2.6 1.4 8.5 0.2 2.2 2 0 0 2 2 2 0 Replication factor-A C terminal domain zf-C2H2 PF00096.21 ETO21868.1 - 0.056 13.8 0.8 0.056 13.8 0.5 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 ETO21868.1 - 0.059 13.5 0.2 0.19 11.8 0.1 2.0 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 ETO21868.1 - 0.1 12.9 0.3 0.1 12.9 0.2 2.4 3 0 0 3 3 3 0 C2H2-type zinc finger Polyketide_cyc2 PF10604.4 ETO21870.1 - 7.4e-05 22.9 0.0 0.00013 22.1 0.0 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport PipA PF07108.6 ETO21871.1 - 0.017 14.5 0.3 0.029 13.7 0.2 1.4 1 0 0 1 1 1 0 PipA protein DUF3973 PF13119.1 ETO21871.1 - 0.02 14.8 0.1 0.066 13.1 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3973) Cu-oxidase_2 PF07731.9 ETO21872.1 - 3.6e-08 33.0 2.1 4.8e-07 29.3 1.3 2.6 2 1 0 2 2 2 1 Multicopper oxidase ATP_Ca_trans_C PF12424.3 ETO21873.1 - 0.011 16.0 0.3 0.041 14.2 0.2 2.0 1 0 0 1 1 1 0 Plasma membrane calcium transporter ATPase C terminal Gemini_AL3 PF01407.12 ETO21874.1 - 0.081 12.3 1.1 0.11 12.0 0.5 1.4 1 1 0 1 1 1 0 Geminivirus AL3 protein DUF764 PF05561.6 ETO21874.1 - 0.29 10.5 4.1 0.28 10.6 0.7 1.9 1 1 2 3 3 3 0 Borrelia burgdorferi protein of unknown function (DUF764) DUF1426 PF07234.6 ETO21874.1 - 1.2 8.8 3.5 1.8 8.3 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1426) Ras PF00071.17 ETO21875.1 - 1.3e-16 60.4 0.2 1.9e-16 59.8 0.1 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO21875.1 - 2.6e-09 37.5 0.1 3.5e-09 37.1 0.1 1.4 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 ETO21875.1 - 9.5e-06 25.5 0.0 1.1e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 ETO21875.1 - 7.4e-05 21.9 0.0 8.7e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arf PF00025.16 ETO21875.1 - 0.001 18.3 0.1 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Septin PF00735.13 ETO21875.1 - 0.0015 17.6 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 Septin AAA_22 PF13401.1 ETO21875.1 - 0.0024 18.0 0.0 0.0029 17.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 ETO21875.1 - 0.0024 18.1 0.1 0.0028 17.9 0.0 1.4 1 1 0 1 1 1 1 ABC transporter NACHT PF05729.7 ETO21875.1 - 0.0034 17.0 0.1 0.0076 15.9 0.0 1.6 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 ETO21875.1 - 0.0036 17.3 0.0 0.0048 16.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain MCM PF00493.18 ETO21875.1 - 0.013 14.3 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family DUF815 PF05673.8 ETO21875.1 - 0.015 14.2 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.9 ETO21875.1 - 0.017 14.8 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 ETO21875.1 - 0.019 14.5 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain IIGP PF05049.8 ETO21875.1 - 0.03 13.1 0.0 0.041 12.6 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Gtr1_RagA PF04670.7 ETO21875.1 - 0.034 13.2 0.1 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RNA_helicase PF00910.17 ETO21875.1 - 0.039 14.1 0.0 0.054 13.6 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.1 ETO21875.1 - 0.059 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 ETO21875.1 - 0.067 13.1 0.0 0.099 12.5 0.0 1.3 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 ETO21875.1 - 0.072 12.3 0.0 0.09 12.0 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B MobB PF03205.9 ETO21875.1 - 0.072 12.7 0.2 0.19 11.4 0.1 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 ETO21875.1 - 0.11 11.9 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 ETO21875.1 - 0.15 11.9 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF3270 PF11674.3 ETO21876.1 - 0.0091 15.9 0.4 0.016 15.2 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3270) Eapp_C PF10238.4 ETO21876.1 - 0.0096 15.8 6.6 0.073 12.9 1.6 2.2 2 0 0 2 2 2 2 E2F-associated phosphoprotein Secretin_N_2 PF07655.8 ETO21876.1 - 0.027 14.8 7.1 0.043 14.2 4.9 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain DUF912 PF06024.7 ETO21876.1 - 2 8.4 11.1 23 5.1 6.6 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF809 PF05663.6 ETO21877.1 - 0.52 10.2 2.5 0.91 9.4 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF809) tRNA-Thr_ED PF08915.6 ETO21877.1 - 0.58 10.1 3.2 0.89 9.5 2.2 1.2 1 0 0 1 1 1 0 Archaea-specific editing domain of threonyl-tRNA synthetase Paramyxo_ncap PF00973.14 ETO21877.1 - 1.2 7.7 7.8 1.7 7.2 5.4 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein PH PF00169.24 ETO21878.1 - 1.2e-10 41.5 2.8 2.5e-10 40.5 2.0 1.5 1 0 0 1 1 1 1 PH domain PH_3 PF14593.1 ETO21878.1 - 2.4e-07 30.5 0.5 4.3e-07 29.7 0.3 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 ETO21878.1 - 7.4e-05 22.9 8.1 0.00045 20.4 2.1 2.5 2 1 1 3 3 3 2 Pleckstrin homology domain PH_6 PF15406.1 ETO21878.1 - 0.002 18.1 0.0 0.0039 17.2 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 ETO21878.1 - 0.0089 16.0 0.3 0.015 15.3 0.2 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain HTH_Tnp_Tc3_2 PF01498.13 ETO21879.1 - 0.22 11.5 1.1 1.5 8.9 0.4 2.3 2 0 0 2 2 2 0 Transposase Ashwin PF15323.1 ETO21879.1 - 2.4 8.1 15.3 3.7 7.4 10.6 1.2 1 0 0 1 1 1 0 Developmental protein Ndc1_Nup PF09531.5 ETO21879.1 - 2.8 6.2 7.5 3.3 6.0 5.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2217 PF10265.4 ETO21879.1 - 4.4 5.9 7.8 5.5 5.6 5.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Peptidase_S55 PF05580.7 ETO21879.1 - 6.9 6.0 8.0 8 5.8 5.1 1.4 1 1 0 1 1 1 0 SpoIVB peptidase S55 Speriolin_C PF15059.1 ETO21880.1 - 0.058 13.4 0.6 0.44 10.5 0.0 2.5 3 0 0 3 3 3 0 Speriolin C-terminus zf-DHHC PF01529.15 ETO21881.1 - 0.00021 20.7 8.2 0.00036 19.9 5.7 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase Glyco_hydro_44 PF12891.2 ETO21881.1 - 0.073 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycoside hydrolase family 44 Methyltransf_26 PF13659.1 ETO21882.1 - 4.9e-07 29.7 0.0 9.6e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO21882.1 - 4.1e-05 24.1 0.0 0.00011 22.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETO21882.1 - 0.1 12.9 0.0 0.34 11.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Secretin_N_2 PF07655.8 ETO21882.1 - 0.27 11.6 28.2 0.15 12.4 17.7 1.9 2 0 0 2 2 2 0 Secretin N-terminal domain Pex14_N PF04695.8 ETO21882.1 - 1.3 9.0 6.6 2.8 7.9 4.5 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF912 PF06024.7 ETO21882.1 - 3 7.9 14.6 7.6 6.6 10.1 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Anoctamin PF04547.7 ETO21883.1 - 1e-30 106.8 10.8 1.3e-30 106.5 7.5 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel NfeD PF01957.13 ETO21883.1 - 0.1 12.7 1.7 0.2 11.7 0.7 1.9 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding ARL6IP6 PF15062.1 ETO21883.1 - 0.68 9.8 2.4 3.2 7.7 0.1 2.6 1 1 1 2 2 2 0 Haemopoietic lineage transmembrane helix Anoctamin PF04547.7 ETO21884.1 - 3.9e-35 121.3 1.7 6.1e-35 120.7 1.2 1.3 1 0 0 1 1 1 1 Calcium-activated chloride channel SPRY PF00622.23 ETO21885.1 - 0.0058 16.7 0.1 0.0097 15.9 0.1 1.3 1 0 0 1 1 1 1 SPRY domain LigB PF02900.13 ETO21886.1 - 7.1e-19 67.8 0.0 6.2e-18 64.7 0.0 2.0 1 1 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Memo PF01875.12 ETO21886.1 - 0.0083 15.0 0.1 0.021 13.7 0.0 1.6 1 1 0 1 1 1 1 Memo-like protein Glycolytic PF00274.14 ETO21887.1 - 5.1e-57 192.8 0.1 6.3e-57 192.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Menin PF05053.8 ETO21889.1 - 6.4 4.8 6.7 8.8 4.3 4.7 1.1 1 0 0 1 1 1 0 Menin EXS PF03124.9 ETO21890.1 - 2e-11 43.5 15.1 2e-11 43.5 10.5 2.1 2 0 0 2 2 2 2 EXS family Virul_fac_BrkB PF03631.10 ETO21891.1 - 0.029 13.7 6.9 0.077 12.3 0.9 2.1 2 0 0 2 2 2 0 Virulence factor BrkB RepA1_leader PF08048.7 ETO21892.1 - 1.3 9.1 5.1 4.6 7.3 3.5 2.0 1 0 0 1 1 1 0 Tap RepA1 leader peptide RRM_1 PF00076.17 ETO21893.1 - 7.6e-14 51.1 0.3 2e-13 49.7 0.2 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO21893.1 - 8.2e-10 38.5 0.0 1.5e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO21893.1 - 0.00015 21.5 0.0 0.0003 20.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spore_coat_CotO PF14153.1 ETO21893.1 - 0.0097 15.3 18.3 0.011 15.1 12.7 1.2 1 0 0 1 1 1 1 Spore coat protein CotO Daxx PF03344.10 ETO21893.1 - 0.038 12.5 21.2 0.039 12.4 14.7 1.0 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 ETO21893.1 - 0.071 11.0 19.0 0.074 10.9 13.2 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 ETO21893.1 - 0.13 11.5 16.9 0.14 11.4 11.7 1.1 1 0 0 1 1 1 0 SDA1 HSP90 PF00183.13 ETO21893.1 - 0.35 9.2 15.8 0.39 9.0 11.0 1.3 1 0 0 1 1 1 0 Hsp90 protein Plasmodium_Vir PF05795.6 ETO21893.1 - 0.43 9.7 5.4 0.51 9.4 3.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4407 PF14362.1 ETO21893.1 - 0.45 9.4 7.6 0.56 9.1 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2457 PF10446.4 ETO21893.1 - 0.64 8.6 13.0 0.69 8.5 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DDHD PF02862.12 ETO21893.1 - 0.88 9.3 7.8 1.4 8.6 5.4 1.4 1 0 0 1 1 1 0 DDHD domain Lin-8 PF03353.10 ETO21893.1 - 1.5 8.0 13.7 1.7 7.8 9.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Pox_RNA_Pol_19 PF05320.7 ETO21893.1 - 1.8 8.2 11.6 2.9 7.6 8.0 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF740 PF05340.7 ETO21893.1 - 2 6.7 15.3 2.2 6.5 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) RRN3 PF05327.6 ETO21893.1 - 2.2 6.3 8.3 2.5 6.0 5.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Neur_chan_memb PF02932.11 ETO21893.1 - 2.2 8.0 5.4 2.8 7.7 3.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.10 ETO21893.1 - 2.3 6.7 10.4 2.6 6.5 7.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DDRGK PF09756.4 ETO21893.1 - 2.5 7.4 26.1 1.4 8.3 16.6 1.6 2 0 0 2 2 2 0 DDRGK domain Tim54 PF11711.3 ETO21893.1 - 2.6 6.5 14.9 3.5 6.1 10.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.9 ETO21893.1 - 3 5.7 17.3 3.6 5.5 12.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.12 ETO21893.1 - 3.4 6.4 8.4 4.3 6.0 5.8 1.1 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.14 ETO21893.1 - 4.7 4.9 10.9 4.8 4.9 7.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ycf1 PF05758.7 ETO21893.1 - 4.9 4.7 16.7 5.2 4.6 11.6 1.0 1 0 0 1 1 1 0 Ycf1 TP53IP5 PF15331.1 ETO21893.1 - 4.9 7.0 10.9 6.7 6.5 7.6 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DUF4045 PF13254.1 ETO21893.1 - 5 6.2 13.0 6.3 5.9 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF966 PF06136.8 ETO21893.1 - 5.1 6.4 8.4 5.2 6.3 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Merozoite_SPAM PF07133.6 ETO21893.1 - 5.4 6.8 33.0 9.5 6.0 22.9 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) GAGA_bind PF06217.7 ETO21893.1 - 7.5 6.4 10.1 9.2 6.1 7.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Sec62 PF03839.11 ETO21893.1 - 8.4 5.7 9.6 12 5.1 6.7 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 TRAP_alpha PF03896.11 ETO21893.1 - 8.9 5.2 17.3 12 4.7 12.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit EIIBC-GUT_N PF03612.9 ETO21893.1 - 9.4 5.8 7.4 26 4.3 5.1 1.8 1 1 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus WD40 PF00400.27 ETO21894.1 - 7.5e-62 203.1 19.3 2.4e-11 43.0 0.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO21894.1 - 5.6e-10 39.2 0.0 0.00015 21.5 0.0 2.7 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO21894.1 - 0.026 12.8 0.2 0.78 7.9 0.0 2.5 1 1 2 3 3 3 0 Cytochrome D1 heme domain Arena_nucleocap PF00843.12 ETO21894.1 - 0.046 11.6 0.1 4.1 5.1 0.0 2.2 2 0 0 2 2 2 0 Arenavirus nucleocapsid protein PD40 PF07676.7 ETO21894.1 - 0.28 10.8 13.6 5.3 6.8 0.1 5.0 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat DUF1406 PF07190.6 ETO21894.1 - 0.34 10.6 2.6 0.71 9.5 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1406) Pkinase PF00069.20 ETO21895.1 - 1.6e-22 79.9 0.2 5.3e-22 78.2 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO21895.1 - 4.1e-06 26.0 0.0 4.8e-05 22.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 ETO21895.1 - 0.059 12.7 0.0 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 RIO1 family TMEM154 PF15102.1 ETO21896.1 - 4.8e-05 23.0 6.2 4.8e-05 23.0 4.3 1.8 1 1 1 2 2 2 1 TMEM154 protein family Rifin_STEVOR PF02009.11 ETO21896.1 - 0.00034 20.3 0.1 0.00034 20.3 0.1 1.5 2 0 0 2 2 2 1 Rifin/stevor family DUF912 PF06024.7 ETO21896.1 - 0.002 18.1 0.7 0.002 18.1 0.5 1.9 1 1 1 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) TRP PF06011.7 ETO21896.1 - 0.0031 16.1 0.5 0.0035 15.9 0.3 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel Amnionless PF14828.1 ETO21896.1 - 0.0045 15.5 0.2 0.0055 15.2 0.1 1.1 1 0 0 1 1 1 1 Amnionless DUF1510 PF07423.6 ETO21896.1 - 0.0063 15.9 0.0 0.009 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Claudin_2 PF13903.1 ETO21896.1 - 0.0079 15.9 0.9 0.01 15.5 0.6 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Nucleoside_tran PF01733.13 ETO21896.1 - 0.0082 15.3 1.0 0.0082 15.3 0.7 1.6 1 1 1 2 2 2 1 Nucleoside transporter Tetraspannin PF00335.15 ETO21896.1 - 0.011 15.0 0.1 0.014 14.7 0.0 1.1 1 0 0 1 1 1 0 Tetraspanin family Peptidase_M56 PF05569.6 ETO21896.1 - 0.012 14.6 0.2 0.016 14.2 0.1 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF1426 PF07234.6 ETO21896.1 - 0.012 15.3 0.1 0.02 14.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1426) Sigma_reg_N PF13800.1 ETO21896.1 - 0.013 15.4 0.1 0.027 14.4 0.1 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal OATP PF03137.15 ETO21896.1 - 0.017 13.2 0.1 0.02 12.9 0.1 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SID-1_RNA_chan PF13965.1 ETO21896.1 - 0.025 12.7 1.0 0.03 12.5 0.7 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 LRR19-TM PF15176.1 ETO21896.1 - 0.037 13.7 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain EVC2_like PF12297.3 ETO21896.1 - 0.04 12.5 0.3 0.053 12.1 0.2 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Pkinase PF00069.20 ETO21896.1 - 0.054 12.6 0.1 0.11 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein kinase domain DUF3377 PF11857.3 ETO21896.1 - 0.1 12.2 0.2 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Shisa PF13908.1 ETO21896.1 - 0.11 12.6 1.9 0.21 11.7 1.3 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator zf-DHHC PF01529.15 ETO21896.1 - 0.11 11.8 0.7 0.15 11.4 0.5 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase Vpu PF00558.14 ETO21896.1 - 0.12 11.9 0.5 0.2 11.2 0.3 1.3 1 0 0 1 1 1 0 Vpu protein DUF3753 PF12575.3 ETO21896.1 - 0.22 11.3 4.9 0.47 10.2 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Mid2 PF04478.7 ETO21896.1 - 0.5 9.7 7.3 0.91 8.9 5.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Atrophin-1 PF03154.10 ETO21896.1 - 0.74 7.8 4.3 0.99 7.4 3.0 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF2393 PF09624.5 ETO21896.1 - 0.87 9.1 8.0 0.85 9.1 5.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2393) Baculo_11_kDa PF06143.6 ETO21896.1 - 4.9 6.5 8.2 9.8 5.6 5.7 1.6 1 1 0 1 1 1 0 Baculovirus 11 kDa family Calpain_III PF01067.17 ETO21897.1 - 0.059 13.0 0.0 0.58 9.7 0.0 2.0 2 0 0 2 2 2 0 Calpain large subunit, domain III UPF0184 PF03670.8 ETO21897.1 - 0.27 11.4 3.0 0.46 10.6 2.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) SH3_1 PF00018.23 ETO21898.1 - 4.1e-32 109.3 4.5 1.2e-15 56.5 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 ETO21898.1 - 2e-26 91.2 0.2 9.9e-16 56.9 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.1 ETO21898.1 - 6.1e-24 83.3 4.7 3.1e-11 42.6 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain VHP PF02209.14 ETO21898.1 - 4.2e-14 51.9 0.6 4.2e-14 51.9 0.4 2.0 2 0 0 2 2 2 1 Villin headpiece domain DUF2659 PF10858.3 ETO21898.1 - 0.009 15.4 1.5 0.019 14.3 1.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2659) DUF2201_N PF13203.1 ETO21898.1 - 0.24 10.5 5.1 0.34 10.0 3.5 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Shisa PF13908.1 ETO21898.1 - 2.9 8.0 8.4 13 5.9 0.5 2.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DAG1 PF05454.6 ETO21898.1 - 5.3 6.1 9.3 0.14 11.3 0.3 2.4 2 1 1 3 3 3 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Vps51 PF08700.6 ETO21899.1 - 1.5e-06 27.9 0.9 1.5e-06 27.9 0.6 2.0 2 0 0 2 2 2 1 Vps51/Vps67 Sec5 PF15469.1 ETO21899.1 - 0.0015 18.3 4.8 0.0028 17.4 3.3 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 Dor1 PF04124.7 ETO21899.1 - 0.0073 14.8 5.9 0.011 14.2 4.1 1.2 1 0 0 1 1 1 1 Dor1-like family COG2 PF06148.6 ETO21899.1 - 0.0079 16.0 4.1 0.018 14.9 2.9 1.6 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.4 ETO21899.1 - 0.0094 15.9 3.6 0.016 15.1 2.5 1.4 1 0 0 1 1 1 1 Golgi transport complex subunit 5 DUF2450 PF10475.4 ETO21899.1 - 0.018 13.9 9.2 0.024 13.5 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Sec8_exocyst PF04048.9 ETO21899.1 - 0.074 12.6 6.4 0.13 11.8 4.4 1.5 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain ORF6N PF10543.4 ETO21899.1 - 0.084 12.9 2.9 0.24 11.4 1.5 2.1 1 1 1 2 2 2 0 ORF6N domain RecX PF02631.11 ETO21899.1 - 0.09 12.9 0.5 0.17 12.1 0.3 1.4 1 0 0 1 1 1 0 RecX family IncA PF04156.9 ETO21899.1 - 0.099 12.2 3.7 0.16 11.5 2.6 1.4 1 0 0 1 1 1 0 IncA protein Ank_2 PF12796.2 ETO21900.1 - 9.4e-66 218.1 17.5 9.7e-19 67.5 0.7 4.8 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 ETO21900.1 - 5.2e-33 111.1 4.4 5.3e-07 29.1 0.1 7.6 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 ETO21900.1 - 1.4e-32 111.4 3.6 1.5e-10 41.2 0.1 7.4 3 1 5 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO21900.1 - 2.9e-30 103.5 9.2 1.3e-09 38.0 0.1 5.8 2 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO21900.1 - 1.5e-26 89.8 0.9 2.2e-05 24.2 0.1 7.9 9 0 0 9 9 9 5 Ankyrin repeat IMP_cyclohyd PF07826.6 ETO21900.1 - 0.078 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 IMP cyclohydrolase-like protein CUE PF02845.11 ETO21901.1 - 0.00063 19.1 0.1 0.0011 18.4 0.1 1.4 1 0 0 1 1 1 1 CUE domain RPA PF10134.4 ETO21901.1 - 0.04 13.1 0.6 0.054 12.7 0.4 1.2 1 0 0 1 1 1 0 Replication initiator protein A Snf7 PF03357.16 ETO21902.1 - 1.8e-10 40.4 20.0 2.3e-10 40.1 13.9 1.1 1 0 0 1 1 1 1 Snf7 ThiC PF01964.13 ETO21902.1 - 0.008 14.7 3.4 0.0092 14.5 2.3 1.1 1 0 0 1 1 1 1 ThiC family Flavi_NS4B PF01349.12 ETO21902.1 - 0.0082 15.1 0.2 0.013 14.4 0.1 1.3 1 0 0 1 1 1 1 Flavivirus non-structural protein NS4B DDE_Tnp_ISL3 PF01610.12 ETO21902.1 - 0.033 13.7 7.7 0.039 13.5 5.2 1.3 1 1 0 1 1 1 0 Transposase DUF840 PF05801.6 ETO21902.1 - 0.14 12.3 1.4 0.15 12.1 0.1 1.7 1 1 1 2 2 2 0 Lagovirus protein of unknown function (DUF840) Luteo_P1-P2 PF08467.5 ETO21902.1 - 0.5 9.1 5.2 0.7 8.6 3.6 1.4 1 1 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase DUF342 PF03961.8 ETO21902.1 - 2.4 6.4 12.1 3.3 6.0 8.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) LOH1CR12 PF10158.4 ETO21902.1 - 9.5 6.0 10.0 2.9 7.6 2.4 2.1 1 1 1 2 2 2 0 Tumour suppressor protein HSD3 PF15244.1 ETO21906.1 - 0.12 11.6 7.1 0.14 11.4 4.9 1.0 1 0 0 1 1 1 0 Hydroxy-steroid dehydrogenase RRM_1 PF00076.17 ETO21907.1 - 1.1e-25 89.0 0.1 2.4e-12 46.2 0.0 2.0 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO21907.1 - 4.5e-18 65.0 0.1 7.3e-08 32.2 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO21907.1 - 1.3e-12 47.4 0.1 1.5e-06 27.9 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETO21907.1 - 3.1e-05 23.6 0.0 0.019 14.7 0.0 2.2 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DUF4283 PF14111.1 ETO21907.1 - 0.0001 21.4 0.2 0.00012 21.2 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4283) RRM_3 PF08777.6 ETO21907.1 - 0.00028 20.6 0.0 0.0029 17.4 0.0 2.0 1 1 1 2 2 2 1 RNA binding motif RNA_bind PF08675.6 ETO21907.1 - 0.0019 18.1 0.0 0.02 14.8 0.0 2.2 2 1 0 2 2 2 1 RNA binding domain NIT PF08376.5 ETO21908.1 - 0.015 14.8 0.4 0.53 9.7 0.0 2.1 1 1 1 2 2 2 0 Nitrate and nitrite sensing Amidohydro_2 PF04909.9 ETO21909.1 - 1.8e-07 30.9 0.0 2.5e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Peptidase_S49_N PF08496.5 ETO21909.1 - 0.12 12.1 1.8 0.17 11.6 1.3 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SPOUT_MTase PF02590.12 ETO21909.1 - 0.16 11.6 1.2 0.28 10.8 0.8 1.3 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase Ribosomal_60s PF00428.14 ETO21909.1 - 5.3 7.5 8.5 38 4.7 5.8 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein Amidohydro_2 PF04909.9 ETO21910.1 - 0.11 12.0 0.0 0.42 10.1 0.0 1.8 1 1 0 1 1 1 0 Amidohydrolase Tubulin PF00091.20 ETO21912.1 - 2.3e-22 79.9 0.0 2.5e-22 79.7 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain SAP PF02037.22 ETO21913.1 - 1.8e-12 46.4 0.6 4.2e-12 45.2 0.0 2.0 2 0 0 2 2 2 1 SAP domain TPT PF03151.11 ETO21914.1 - 1.6e-18 66.8 8.9 1.6e-18 66.8 6.1 2.3 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 ETO21914.1 - 0.34 10.9 35.9 1.7 8.7 10.2 3.1 2 2 1 3 3 3 0 EamA-like transporter family M_domain PF12938.2 ETO21915.1 - 0.33 10.7 6.1 0.49 10.1 4.2 1.2 1 0 0 1 1 1 0 M domain of GW182 HA2 PF04408.18 ETO21916.1 - 1.5e-21 76.2 0.0 3.1e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 ETO21916.1 - 1.2e-13 50.8 0.0 3.1e-13 49.5 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 ETO21916.1 - 1.9e-11 43.6 0.0 4.5e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETO21916.1 - 2.7e-11 43.2 0.4 4.9e-11 42.4 0.3 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.13 ETO21916.1 - 2.8e-05 23.6 0.3 0.00011 21.7 0.0 2.1 3 0 0 3 3 3 1 FtsK/SpoIIIE family ResIII PF04851.10 ETO21916.1 - 3.5e-05 23.7 0.5 0.0012 18.7 0.3 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 ETO21916.1 - 0.00017 21.7 0.0 0.00044 20.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 ETO21916.1 - 0.00034 20.2 1.5 0.02 14.4 0.1 2.6 3 0 0 3 3 2 1 AAA domain DUF2075 PF09848.4 ETO21916.1 - 0.00043 19.3 0.1 0.0007 18.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 ETO21916.1 - 0.00048 19.8 0.2 0.0011 18.6 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain SRP54 PF00448.17 ETO21916.1 - 0.00054 19.4 0.9 0.0015 17.9 0.6 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain T2SE PF00437.15 ETO21916.1 - 0.00096 18.1 0.2 0.0018 17.2 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 ETO21916.1 - 0.0027 17.7 0.0 0.0072 16.3 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 ETO21916.1 - 0.0029 17.2 0.1 0.0088 15.7 0.0 1.8 2 0 0 2 2 2 1 NACHT domain UvrD-helicase PF00580.16 ETO21916.1 - 0.0033 16.7 0.1 0.0059 15.9 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_30 PF13604.1 ETO21916.1 - 0.0041 16.7 0.1 0.0076 15.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 ETO21916.1 - 0.0096 15.8 0.1 0.34 10.8 0.0 3.3 3 2 0 3 3 2 1 AAA domain PhoH PF02562.11 ETO21916.1 - 0.012 14.8 0.5 0.044 13.0 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_29 PF13555.1 ETO21916.1 - 0.02 14.3 0.0 0.054 13.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 ETO21916.1 - 0.022 13.8 0.6 0.13 11.3 0.1 2.1 1 1 1 2 2 2 0 Zeta toxin ABC_tran PF00005.22 ETO21916.1 - 0.035 14.3 0.0 0.086 13.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter KaiC PF06745.8 ETO21916.1 - 0.04 13.0 0.0 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 KaiC CHCH PF06747.8 ETO21916.1 - 0.046 13.6 1.7 0.12 12.3 0.3 2.3 2 0 0 2 2 2 0 CHCH domain TrwB_AAD_bind PF10412.4 ETO21916.1 - 0.046 12.3 0.1 0.078 11.5 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Flavoprotein PF02441.14 ETO21916.1 - 0.052 13.2 0.1 0.42 10.2 0.0 2.4 2 0 0 2 2 2 0 Flavoprotein AAA_33 PF13671.1 ETO21916.1 - 0.068 13.0 0.1 0.48 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 ETO21916.1 - 0.071 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF4611 PF15387.1 ETO21916.1 - 0.072 13.2 0.9 0.15 12.2 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) AAA_17 PF13207.1 ETO21916.1 - 0.58 10.9 3.1 2.4 8.9 0.7 3.2 4 0 0 4 4 2 0 AAA domain Myotub-related PF06602.9 ETO21917.1 - 1.5e-68 231.2 0.8 2e-68 230.7 0.5 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.15 ETO21917.1 - 0.0022 17.5 0.3 0.0088 15.6 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 ETO21917.1 - 0.0025 17.1 0.0 0.0043 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 ETO21917.1 - 0.0054 17.0 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family CBP PF12192.3 ETO21917.1 - 0.61 10.0 0.1 0.61 10.0 0.0 1.9 2 0 0 2 2 2 0 Fungal calcium binding protein GDI PF00996.13 ETO21918.1 - 6.8e-29 100.4 0.6 7.6e-29 100.2 0.4 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor RRM_1 PF00076.17 ETO21919.1 - 2e-17 62.5 0.0 4.4e-17 61.4 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO21919.1 - 3.3e-11 43.0 0.0 6.2e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO21919.1 - 1.6e-07 31.0 0.0 3.1e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETO21919.1 - 5.6e-05 22.8 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif SVWC PF15430.1 ETO21920.1 - 0.078 13.4 2.6 0.19 12.1 1.8 1.6 1 0 0 1 1 1 0 Single domain von Willebrand factor type C CytochromB561_N PF09786.4 ETO21920.1 - 0.45 8.9 10.2 0.92 7.8 7.1 1.4 1 0 0 1 1 1 0 Cytochrome B561, N terminal Opiods_neuropep PF01160.13 ETO21921.1 - 0.016 14.9 1.0 0.037 13.7 0.7 1.5 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide Coat_X PF07552.6 ETO21921.1 - 0.027 14.2 2.1 0.15 11.8 0.1 2.6 3 0 0 3 3 3 0 Spore Coat Protein X and V domain DUF1735 PF08522.5 ETO21921.1 - 0.043 14.2 0.8 0.15 12.5 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1735) GDA1_CD39 PF01150.12 ETO21922.1 - 2.4e-30 105.4 6.3 8.6e-29 100.2 0.3 3.0 2 1 1 3 3 3 2 GDA1/CD39 (nucleoside phosphatase) family DUF3128 PF11326.3 ETO21922.1 - 0.13 12.3 0.3 0.34 11.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) ADSL_C PF10397.4 ETO21923.1 - 0.036 14.0 0.0 0.08 12.9 0.0 1.5 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminus TF_Zn_Ribbon PF08271.7 ETO21923.1 - 0.06 12.6 0.2 0.13 11.5 0.1 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding His_Phos_1 PF00300.17 ETO21923.1 - 0.086 12.9 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) I_LWEQ PF01608.12 ETO21923.1 - 0.21 11.5 1.4 1.4 8.8 0.8 2.0 1 1 0 1 1 1 0 I/LWEQ domain GTP_EFTU PF00009.22 ETO21924.1 - 0.00095 18.6 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 ETO21925.1 - 1.4e-05 25.1 0.2 2.6e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain Ribosomal_L13 PF00572.13 ETO21925.1 - 0.0077 16.2 2.0 0.37 10.8 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein L13 DUF2457 PF10446.4 ETO21925.1 - 0.048 12.3 14.4 0.12 11.1 10.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sigma70_ner PF04546.8 ETO21925.1 - 0.13 11.8 2.7 0.29 10.7 1.9 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Upf2 PF04050.9 ETO21925.1 - 0.44 10.3 7.6 0.89 9.2 5.3 1.5 1 0 0 1 1 1 0 Up-frameshift suppressor 2 CDC45 PF02724.9 ETO21925.1 - 7.2 4.5 8.3 12 3.8 5.8 1.2 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.27 ETO21926.1 - 1.2e-159 513.1 39.6 3.6e-12 45.6 0.1 14.4 14 0 0 14 14 14 14 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO21926.1 - 3e-12 45.5 10.7 0.008 14.5 0.1 6.5 1 1 7 8 8 8 5 Cytochrome D1 heme domain NACHT PF05729.7 ETO21926.1 - 9e-09 35.2 0.0 2.2e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Nucleoporin_N PF08801.6 ETO21926.1 - 2.5e-08 33.1 22.4 0.04 12.6 0.5 8.0 1 1 3 5 5 5 5 Nup133 N terminal like Proteasome_A_N PF10584.4 ETO21926.1 - 7e-06 25.2 7.3 5.1 6.5 0.0 7.5 8 0 0 8 8 8 1 Proteasome subunit A N-terminal signature Pentapeptide PF00805.17 ETO21926.1 - 7.7e-06 25.0 2.3 1.5e-05 24.0 1.6 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO21926.1 - 0.00013 21.6 0.2 0.00031 20.4 0.2 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA_18 PF13238.1 ETO21926.1 - 0.00049 20.4 0.7 0.0021 18.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETO21926.1 - 0.00055 20.0 0.0 0.0016 18.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain Pentapeptide_3 PF13576.1 ETO21926.1 - 0.0011 18.7 0.4 0.0063 16.3 0.4 2.1 1 1 1 2 2 2 1 Pentapeptide repeats (9 copies) Torsin PF06309.6 ETO21926.1 - 0.0018 18.1 1.4 0.013 15.3 0.1 2.5 2 0 0 2 2 2 1 Torsin UPF0079 PF02367.12 ETO21926.1 - 0.0036 16.9 0.1 0.051 13.1 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 PD40 PF07676.7 ETO21926.1 - 0.015 14.9 12.9 26 4.5 0.1 7.6 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat AAA_17 PF13207.1 ETO21926.1 - 0.044 14.5 0.0 0.24 12.2 0.0 2.4 1 0 0 1 1 1 0 AAA domain DUF2527 PF10736.4 ETO21926.1 - 0.049 13.2 0.0 2.2 7.9 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2627) AAA_16 PF13191.1 ETO21926.1 - 0.11 12.4 0.5 2.1 8.2 0.0 3.1 2 2 2 4 4 4 0 AAA ATPase domain DUF1211 PF06736.6 ETO21929.1 - 0.048 13.8 0.8 0.1 12.7 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1211) DUF4094 PF13334.1 ETO21930.1 - 1.1 9.6 4.2 1.6 9.1 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Secretin_N_2 PF07655.8 ETO21930.1 - 1.2 9.5 11.2 3.4 8.1 7.8 1.8 1 0 0 1 1 1 0 Secretin N-terminal domain SCO1-SenC PF02630.9 ETO21931.1 - 0.0059 16.2 1.2 0.0074 15.9 0.9 1.2 1 0 0 1 1 1 1 SCO1/SenC WXG100 PF06013.7 ETO21931.1 - 0.066 13.2 0.8 0.066 13.2 0.6 1.7 2 0 0 2 2 2 0 Proteins of 100 residues with WXG CPSF_A PF03178.10 ETO21932.1 - 1.1e-36 126.5 1.7 1.6e-36 126.0 1.2 1.2 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.4 ETO21933.1 - 1.6e-31 109.0 0.3 2.4e-31 108.4 0.2 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term 7TM_GPCR_Srx PF10328.4 ETO21934.1 - 0.2 10.7 3.8 0.19 10.8 0.7 1.9 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx DnaJ PF00226.26 ETO21936.1 - 0.024 14.3 0.0 0.066 12.9 0.0 1.8 1 1 0 1 1 1 0 DnaJ domain Nexin_C PF08628.7 ETO21936.1 - 0.036 14.1 0.2 0.3 11.1 0.1 2.2 2 0 0 2 2 2 0 Sorting nexin C terminal Rick_17kDa_Anti PF05433.10 ETO21936.1 - 0.054 13.1 9.6 0.53 9.9 2.7 2.4 2 0 0 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 ETO21936.1 - 0.18 11.4 11.0 0.28 10.8 2.8 2.4 2 0 0 2 2 2 0 Glycine zipper DUF843 PF05814.6 ETO21936.1 - 0.52 10.1 5.2 2.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) Iron_permease PF04120.7 ETO21937.1 - 0.12 11.9 0.6 0.2 11.2 0.1 1.5 1 1 1 2 2 2 0 Low affinity iron permease Nup88 PF10168.4 ETO21937.1 - 0.54 8.0 2.7 0.62 7.8 1.9 1.0 1 0 0 1 1 1 0 Nuclear pore component TMEM154 PF15102.1 ETO21937.1 - 4.9 6.8 7.1 8.4 6.0 3.9 1.9 1 1 1 2 2 2 0 TMEM154 protein family YajC PF02699.10 ETO21937.1 - 8.7 6.0 7.5 1.7 8.3 2.7 1.8 2 1 0 2 2 2 0 Preprotein translocase subunit Ctr PF04145.10 ETO21938.1 - 0.17 11.9 8.7 4.6 7.2 0.1 4.3 3 1 1 4 4 4 0 Ctr copper transporter family DUF912 PF06024.7 ETO21938.1 - 0.41 10.7 17.6 3.7 7.6 2.2 4.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pex14_N PF04695.8 ETO21938.1 - 0.56 10.2 16.2 1.3 9.0 1.6 3.5 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Zip PF02535.17 ETO21938.1 - 0.97 8.3 8.7 3.7 6.4 0.8 2.7 3 0 0 3 3 3 0 ZIP Zinc transporter RP-C_C PF11800.3 ETO21938.1 - 3.4 7.2 9.5 9.9 5.8 0.3 3.1 3 0 0 3 3 3 0 Replication protein C C-terminal region DUF3408 PF11888.3 ETO21938.1 - 8.4 6.3 14.3 0.17 11.7 3.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) DUF2431 PF10354.4 ETO21939.1 - 0.046 13.6 0.2 0.1 12.5 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2431) HlyIII PF03006.15 ETO21940.1 - 3.3e-21 75.7 22.7 3.3e-21 75.7 15.7 2.1 1 1 1 2 2 2 2 Haemolysin-III related KSR1-SAM PF13543.1 ETO21942.1 - 0.0066 16.2 0.2 0.0066 16.2 0.1 2.0 2 0 0 2 2 2 1 SAM like domain present in kinase suppressor RAS 1 B56 PF01603.15 ETO21943.1 - 8.2e-05 21.3 0.1 0.00013 20.7 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) BLVR PF06375.6 ETO21943.1 - 0.28 10.9 5.9 0.38 10.5 4.1 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) CPSF100_C PF13299.1 ETO21944.1 - 1e-06 29.0 5.0 1.7e-06 28.2 3.5 1.4 1 1 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Menin PF05053.8 ETO21944.1 - 0.029 12.5 4.5 0.034 12.3 3.1 1.1 1 0 0 1 1 1 0 Menin Secretin_N_2 PF07655.8 ETO21944.1 - 3.4 8.1 27.6 12 6.3 16.4 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain Apc15p PF05841.6 ETO21944.1 - 4.7 7.9 14.5 1.4 9.6 8.1 1.6 2 0 0 2 2 2 0 Apc15p protein DUF912 PF06024.7 ETO21944.1 - 9.3 6.3 12.0 19 5.3 8.3 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) WD40 PF00400.27 ETO21946.1 - 3.6e-54 178.8 31.7 3.8e-11 42.4 0.9 7.3 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO21946.1 - 4.4e-13 48.2 7.2 0.00012 20.4 0.1 4.9 1 1 4 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO21946.1 - 0.095 11.4 10.8 1.8 7.2 0.6 4.1 1 1 2 4 4 4 0 Nup133 N terminal like TPR_11 PF13414.1 ETO21947.1 - 7e-23 80.0 5.4 2.2e-12 46.4 0.2 2.3 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETO21947.1 - 3.8e-15 54.7 0.9 9.4e-07 28.1 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO21947.1 - 2.2e-13 49.0 0.9 3.5e-05 23.3 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO21947.1 - 1.5e-09 36.9 3.2 0.0031 17.1 0.0 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO21947.1 - 1.7e-07 31.0 5.0 1.7e-07 31.0 0.3 2.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO21947.1 - 1.8e-07 31.6 0.2 0.011 16.4 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat Prefoldin_2 PF01920.15 ETO21947.1 - 1.4e-06 28.0 0.4 1.4e-06 28.0 0.3 3.0 2 1 1 3 3 3 1 Prefoldin subunit TPR_7 PF13176.1 ETO21947.1 - 2e-06 27.1 3.4 0.21 11.4 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO21947.1 - 4.2e-06 26.9 0.6 0.026 15.1 0.1 3.7 2 1 2 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETO21947.1 - 6.3e-06 25.9 0.5 2.8e-05 23.8 0.2 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO21947.1 - 1.1e-05 25.5 5.1 0.044 14.2 0.3 4.3 4 1 1 5 5 4 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO21947.1 - 1.7e-05 24.8 4.1 3.5e-05 23.8 2.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO21947.1 - 2e-05 24.8 6.6 0.074 13.4 1.3 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO21947.1 - 9.8e-05 22.2 1.2 0.061 13.5 0.1 3.4 4 0 0 4 4 2 1 Tetratricopeptide repeat TPR_20 PF14561.1 ETO21947.1 - 0.00062 19.8 4.0 0.0052 16.8 1.3 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.1 ETO21947.1 - 0.0024 17.0 4.7 0.13 11.3 1.6 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat EcoEI_R_C PF08463.5 ETO21947.1 - 0.025 14.4 2.2 0.025 14.4 1.5 1.9 2 0 0 2 2 2 0 EcoEI R protein C-terminal Fis1_TPR_C PF14853.1 ETO21947.1 - 0.045 13.6 3.4 0.18 11.7 0.7 2.6 1 1 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat HlyD PF00529.15 ETO21947.1 - 0.49 9.6 11.4 1.2 8.4 7.9 1.7 1 1 0 1 1 1 0 HlyD family secretion protein DUF3782 PF12644.2 ETO21947.1 - 6.2 6.6 7.5 49 3.8 3.9 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3782) UbiA PF01040.13 ETO21948.1 - 1.5e-11 43.9 15.1 3.9e-11 42.6 10.3 1.8 1 1 0 1 1 1 1 UbiA prenyltransferase family Vps35 PF03635.12 ETO21949.1 - 6e-15 54.4 2.4 8.4e-15 54.0 1.6 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 WD40 PF00400.27 ETO21952.1 - 5.2e-73 238.5 10.8 9e-13 47.5 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO21952.1 - 8.5e-15 54.9 0.2 3.3e-08 33.4 0.0 3.4 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO21952.1 - 7e-09 34.4 0.2 0.00092 17.5 0.0 2.8 2 1 1 3 3 3 3 Cytochrome D1 heme domain Nup160 PF11715.3 ETO21952.1 - 8.6e-08 30.7 2.4 2.2 6.2 0.0 5.5 1 1 3 5 5 5 4 Nucleoporin Nup120/160 PD40 PF07676.7 ETO21952.1 - 1.7e-06 27.5 6.4 3.8 7.2 0.0 6.5 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO21952.1 - 4.3e-06 25.7 7.6 0.25 10.0 0.0 4.6 1 1 3 4 4 4 3 Nup133 N terminal like PQQ_2 PF13360.1 ETO21952.1 - 1.7e-05 24.3 1.9 0.0071 15.8 1.3 2.7 1 1 0 1 1 1 1 PQQ-like domain IKI3 PF04762.7 ETO21952.1 - 0.00049 18.0 1.0 0.68 7.6 0.1 2.9 1 1 2 3 3 3 2 IKI3 family Str_synth PF03088.11 ETO21952.1 - 0.0026 17.7 0.0 8.4 6.5 0.0 3.8 3 1 1 4 4 4 1 Strictosidine synthase DUF4221 PF13970.1 ETO21952.1 - 0.0082 15.5 0.0 4.9 6.3 0.0 3.3 1 1 2 4 4 4 1 Domain of unknown function (DUF4221) Me-amine-dh_H PF06433.6 ETO21952.1 - 0.014 14.0 0.0 2.3 6.7 0.0 2.4 1 1 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) DUF1652 PF07865.6 ETO21952.1 - 0.016 14.7 0.1 2.3 7.8 0.0 3.8 4 2 2 6 6 6 0 Protein of unknown function (DUF1652) DUF1914 PF08932.5 ETO21952.1 - 0.026 14.5 1.8 0.22 11.5 0.0 3.0 3 2 0 3 3 3 0 Domain of unknown function (DUF1914) Resistin PF06954.6 ETO21952.1 - 0.049 13.8 0.1 22 5.4 0.0 3.4 3 1 1 4 4 4 0 Resistin TFIIIC_delta PF12657.2 ETO21952.1 - 0.066 12.9 1.2 32 4.1 0.0 3.3 2 1 1 3 3 3 0 Transcription factor IIIC subunit delta N-term Mid2 PF04478.7 ETO21952.1 - 0.42 10.0 2.7 7.9 5.8 0.0 3.8 3 2 2 5 5 5 0 Mid2 like cell wall stress sensor Proteasome_A_N PF10584.4 ETO21952.1 - 3.3 7.1 7.9 48 3.4 0.0 4.5 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature DUF412 PF04217.8 ETO21953.1 - 0.046 13.5 1.2 0.053 13.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF412 DUF2115 PF09888.4 ETO21953.1 - 2 8.4 8.6 1.4 9.0 4.2 2.0 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) Synapsin_C PF02750.9 ETO21954.1 - 1.2e-16 60.4 0.3 1.7e-16 59.9 0.2 1.2 1 0 0 1 1 1 1 Synapsin, ATP binding domain RhoGEF PF00621.15 ETO21955.1 - 1.2e-39 136.0 5.8 1.2e-39 136.0 4.0 2.4 2 1 0 2 2 2 1 RhoGEF domain FYVE PF01363.16 ETO21955.1 - 7.6e-14 51.3 8.8 1.7e-13 50.2 6.1 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 ETO21955.1 - 0.0037 17.1 4.0 0.0037 17.1 2.7 2.6 2 0 0 2 2 2 1 FYVE-type zinc finger Menin PF05053.8 ETO21955.1 - 0.015 13.5 1.8 0.027 12.6 1.3 1.4 1 0 0 1 1 1 0 Menin DUF2721 PF11026.3 ETO21955.1 - 1.7 8.2 3.3 7.9 6.1 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Peptidase_M1 PF01433.15 ETO21957.1 - 4.7e-96 322.2 0.4 5.9e-96 321.9 0.3 1.0 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 ETO21957.1 - 1e-11 44.9 0.2 1.6e-11 44.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase MA superfamily WLM PF08325.5 ETO21957.1 - 0.04 13.8 0.0 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 WLM domain Peptidase_M1 PF01433.15 ETO21958.1 - 7.5e-07 28.5 0.0 2e-06 27.1 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 ETO21958.1 - 0.0091 16.0 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily NatB_MDM20 PF09797.4 ETO21958.1 - 0.089 11.4 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit DivIC PF04977.10 ETO21959.1 - 0.021 14.3 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 Septum formation initiator EzrA PF06160.7 ETO21959.1 - 0.024 12.8 0.0 0.033 12.3 0.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TSC22 PF01166.13 ETO21959.1 - 0.029 14.3 3.0 0.13 12.2 0.8 2.6 2 1 1 3 3 3 0 TSC-22/dip/bun family SseC PF04888.7 ETO21959.1 - 0.038 13.3 0.1 0.043 13.1 0.0 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DNA_pol_B_2 PF03175.8 ETO21959.1 - 0.055 12.1 0.2 0.061 11.9 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral Nsp1_C PF05064.8 ETO21959.1 - 0.08 12.5 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Nsp1-like C-terminal region GAS PF13851.1 ETO21959.1 - 0.31 10.1 4.9 0.1 11.8 1.2 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Tudor-knot PF11717.3 ETO21960.1 - 0.0047 16.5 0.1 0.02 14.5 0.1 2.1 1 1 0 1 1 1 1 RNA binding activity-knot of a chromodomain Nucleoplasmin PF03066.10 ETO21960.1 - 1.4 8.4 11.2 3.5 7.1 7.8 1.7 1 0 0 1 1 1 0 Nucleoplasmin DUF3340 PF11818.3 ETO21961.1 - 0.041 13.8 0.4 0.055 13.4 0.3 1.2 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) Menin PF05053.8 ETO21962.1 - 0.11 10.6 5.2 0.1 10.7 3.6 1.1 1 0 0 1 1 1 0 Menin Apis_Csd PF11671.3 ETO21962.1 - 0.19 11.5 3.6 0.31 10.8 2.5 1.5 1 0 0 1 1 1 0 Complementary sex determiner protein RRM_1 PF00076.17 ETO21963.1 - 7.8e-43 143.9 7.9 2.3e-14 52.7 0.2 7.3 7 0 0 7 7 7 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO21963.1 - 3.5e-35 119.8 3.8 1.1e-10 41.2 0.1 8.2 7 1 0 7 7 7 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO21963.1 - 9.2e-16 57.4 6.1 1.9e-05 24.3 0.2 5.8 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_1 PF00013.24 ETO21963.1 - 0.00047 19.7 0.2 0.021 14.4 0.0 3.5 3 0 0 3 3 3 1 KH domain KH_3 PF13014.1 ETO21963.1 - 0.0005 19.6 0.0 0.086 12.5 0.0 3.0 2 0 0 2 2 2 1 KH domain TLD PF07534.11 ETO21964.1 - 8.5e-33 113.2 0.5 1.7e-32 112.3 0.3 1.5 1 0 0 1 1 1 1 TLD BLVR PF06375.6 ETO21964.1 - 0.05 13.4 4.0 0.1 12.4 2.8 1.4 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) DUF2162 PF09930.4 ETO21964.1 - 0.21 10.6 0.7 0.34 10.0 0.0 1.6 2 0 0 2 2 2 0 Predicted transporter (DUF2162) FH2 PF02181.18 ETO21965.1 - 0.067 12.0 0.0 0.083 11.7 0.0 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain Solute_trans_a PF03619.11 ETO21966.1 - 4.1e-63 213.2 17.3 2.6e-54 184.3 6.4 2.2 1 1 1 2 2 2 2 Organic solute transporter Ostalpha PAN_3 PF08277.7 ETO21966.1 - 0.19 11.3 3.0 5.6 6.6 1.0 2.4 2 0 0 2 2 2 0 PAN-like domain RGS PF00615.14 ETO21967.1 - 0.02 14.9 0.4 0.037 14.1 0.3 1.4 1 0 0 1 1 1 0 Regulator of G protein signaling domain CAT PF00302.13 ETO21967.1 - 0.034 13.7 0.4 0.22 11.1 0.1 2.1 2 0 0 2 2 2 0 Chloramphenicol acetyltransferase MtN3_slv PF03083.11 ETO21967.1 - 0.13 12.1 6.4 5.5 6.9 1.5 2.5 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange PCI PF01399.22 ETO21968.1 - 0.087 13.1 0.8 0.21 11.9 0.2 2.0 2 1 0 2 2 2 0 PCI domain Pkinase PF00069.20 ETO21969.1 - 2.1e-60 204.0 0.9 2.1e-60 204.0 0.6 2.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO21969.1 - 2.3e-28 98.9 1.8 8e-22 77.5 0.6 2.8 1 1 2 3 3 3 2 Protein tyrosine kinase APH PF01636.18 ETO21969.1 - 0.0023 17.7 0.1 0.011 15.4 0.1 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 ETO21969.1 - 0.0067 15.5 0.0 0.016 14.2 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETO21969.1 - 0.014 14.3 3.0 0.016 14.1 0.0 2.5 3 1 1 4 4 4 0 Kinase-like LETM1 PF07766.8 ETO21970.1 - 9.8e-43 146.1 2.7 1.1e-42 145.8 1.9 1.0 1 0 0 1 1 1 1 LETM1-like protein Acetyltransf_6 PF13480.1 ETO21970.1 - 0.13 12.1 0.3 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain MmgE_PrpD PF03972.9 ETO21972.1 - 9.3e-31 106.4 0.2 4.8e-28 97.5 0.1 2.3 1 1 0 2 2 2 2 MmgE/PrpD family DUF2154 PF09922.4 ETO21973.1 - 0.0023 17.6 0.4 0.0065 16.1 0.1 1.8 2 0 0 2 2 2 1 Cell wall-active antibiotics response protein (DUF2154) DUF1919 PF08942.5 ETO21973.1 - 0.02 14.2 0.3 0.042 13.2 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1919) HAMP PF00672.20 ETO21973.1 - 0.081 13.1 0.1 0.081 13.1 0.0 1.6 2 0 0 2 2 2 0 HAMP domain Pkinase PF00069.20 ETO21974.1 - 9.1e-10 38.1 0.2 1.2e-09 37.7 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO21974.1 - 1.3e-05 24.4 0.2 1.7e-05 23.9 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Utp14 PF04615.8 ETO21974.1 - 0.2 9.7 9.7 0.21 9.7 6.7 1.0 1 0 0 1 1 1 0 Utp14 protein YL1 PF05764.8 ETO21974.1 - 0.36 10.4 9.5 0.43 10.1 6.6 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DUF2262 PF10020.4 ETO21974.1 - 0.67 10.1 5.8 0.79 9.9 4.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2262) TRAUB PF08164.7 ETO21974.1 - 6.4 6.9 7.3 6.2 7.0 3.9 1.9 1 1 1 2 2 2 0 Apoptosis-antagonizing transcription factor, C-terminal Tubulin PF00091.20 ETO21975.1 - 4.7e-33 114.8 0.0 6.1e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO21976.1 - 4.9e-05 23.3 0.0 9.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain AT_hook PF02178.14 ETO21977.1 - 2.1 8.2 21.6 5.7 6.9 3.8 2.7 2 0 0 2 2 2 0 AT hook motif CAP_N PF01213.14 ETO21978.1 - 0.097 11.9 8.4 0.21 10.8 5.8 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SpaB_C PF14028.1 ETO21978.1 - 0.12 11.9 1.7 3.3 7.1 0.0 2.1 1 1 0 2 2 2 0 SpaB C-terminal domain Rota_VP2 PF05087.7 ETO21979.1 - 0.63 7.8 8.7 2.5 5.8 6.7 1.5 2 0 0 2 2 2 0 Rotavirus VP2 protein SPX PF03105.14 ETO21980.1 - 0.0093 15.7 1.6 0.012 15.4 1.1 1.0 1 0 0 1 1 1 1 SPX domain Adenine_deam_C PF13382.1 ETO21980.1 - 0.041 13.0 0.0 0.059 12.5 0.0 1.3 1 0 0 1 1 1 0 Adenine deaminase C-terminal domain DUF4251 PF14059.1 ETO21980.1 - 0.066 13.0 0.4 0.098 12.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4251) DUF1694 PF07997.6 ETO21980.1 - 0.081 12.8 0.7 0.097 12.6 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1694) Rod_cone_degen PF15201.1 ETO21980.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Progressive rod-cone degeneration APG6 PF04111.7 ETO21980.1 - 0.2 10.6 3.5 0.25 10.3 2.4 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 TFIIF_alpha PF05793.7 ETO21981.1 - 2.7 6.2 22.9 4.1 5.6 15.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RRN3 PF05327.6 ETO21981.1 - 9.8 4.1 11.5 2.6 6.0 5.7 1.8 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 NOSIC PF08060.8 ETO21982.1 - 4.3e-25 87.2 0.2 8.2e-25 86.3 0.1 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 ETO21982.1 - 4.3e-16 58.8 0.5 7.7e-16 58.0 0.3 1.4 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Tis11B_N PF04553.7 ETO21985.1 - 1.1 9.4 4.2 1.4 9.0 0.0 2.5 2 1 0 2 2 2 0 Tis11B like protein, N terminus DUF3446 PF11928.3 ETO21985.1 - 4.8 7.4 7.1 0.61 10.3 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3446) Med19 PF10278.4 ETO21986.1 - 0.45 10.1 11.6 0.72 9.5 8.0 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Kinesin PF00225.18 ETO21987.1 - 2.9e-38 131.4 1.8 6.9e-37 126.8 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain DUF1192 PF06698.6 ETO21987.1 - 0.0016 18.2 4.2 0.13 12.0 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1192) DUF4407 PF14362.1 ETO21987.1 - 0.0062 15.5 3.9 0.0094 14.9 2.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) PBP_dimer PF03717.10 ETO21987.1 - 0.036 14.1 5.6 0.047 13.7 3.7 1.3 1 1 0 1 1 1 0 Penicillin-binding Protein dimerisation domain Rpn3_C PF08375.6 ETO21987.1 - 0.062 13.7 1.4 0.12 12.8 0.0 2.0 2 0 0 2 2 2 0 Proteasome regulatory subunit C-terminal DUF3206 PF11472.3 ETO21987.1 - 0.086 12.6 0.2 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3206) HrpB7 PF09486.5 ETO21987.1 - 0.15 11.9 3.4 7.9 6.3 0.3 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Nit_Regul_Hom PF10126.4 ETO21987.1 - 0.16 11.7 1.5 0.27 11.0 0.7 1.6 1 1 0 1 1 1 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII IncA PF04156.9 ETO21987.1 - 0.16 11.5 10.2 1.5 8.3 7.2 2.0 1 1 1 2 2 2 0 IncA protein Ycf4 PF02392.11 ETO21987.1 - 0.17 11.2 1.3 0.22 10.8 0.9 1.2 1 0 0 1 1 1 0 Ycf4 MerR-DNA-bind PF09278.6 ETO21987.1 - 0.2 12.0 4.0 6.9 7.1 0.1 2.5 2 0 0 2 2 2 0 MerR, DNA binding Atg14 PF10186.4 ETO21987.1 - 0.25 10.2 12.8 0.42 9.4 8.9 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1759 PF03564.10 ETO21987.1 - 0.27 11.0 5.4 3 7.6 3.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) Mnd1 PF03962.10 ETO21987.1 - 0.36 10.4 9.1 0.54 9.9 6.3 1.2 1 0 0 1 1 1 0 Mnd1 family Prefoldin_2 PF01920.15 ETO21987.1 - 0.47 10.2 15.7 1.4 8.7 1.7 2.3 2 0 0 2 2 2 0 Prefoldin subunit DUF4200 PF13863.1 ETO21987.1 - 0.56 10.1 14.0 4.7 7.1 9.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Med9 PF07544.8 ETO21987.1 - 0.99 9.1 12.3 1.3 8.7 2.6 2.3 1 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Tropomyosin_1 PF12718.2 ETO21987.1 - 1.2 9.0 15.8 2.4 8.0 11.0 1.5 1 1 0 1 1 1 0 Tropomyosin like PspB PF06667.7 ETO21987.1 - 1.3 8.9 6.3 6.3 6.8 0.2 2.9 3 0 0 3 3 3 0 Phage shock protein B FliT PF05400.8 ETO21987.1 - 1.8 9.0 8.5 3.9 7.9 0.5 3.0 3 0 0 3 3 3 0 Flagellar protein FliT SlyX PF04102.7 ETO21987.1 - 3 8.2 7.4 12 6.3 0.5 2.4 2 0 0 2 2 2 0 SlyX Sec2p PF06428.6 ETO21987.1 - 3.7 7.4 13.4 33 4.3 1.7 2.2 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Val_tRNA-synt_C PF10458.4 ETO21987.1 - 4.6 7.4 10.3 25 5.0 7.1 2.1 1 1 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm H-kinase_dim PF02895.9 ETO21987.1 - 7.9 6.9 7.4 6.5 7.1 0.3 2.8 3 0 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain Drf_FH3 PF06367.11 ETO21988.1 - 2.8e-06 26.8 1.5 6.9e-06 25.6 0.2 2.2 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 ETO21988.1 - 0.34 10.2 3.1 0.25 10.6 0.3 2.1 2 1 0 2 2 2 0 Diaphanous GTPase-binding Domain PCI PF01399.22 ETO21990.1 - 3e-07 30.7 0.7 6.4e-07 29.6 0.1 2.0 2 1 0 2 2 2 1 PCI domain HTH_17 PF12728.2 ETO21990.1 - 0.013 15.7 0.1 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_Cox PF10743.4 ETO21990.1 - 0.017 15.0 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 Regulatory phage protein cox DUF1347 PF07079.6 ETO21991.1 - 0.00012 20.5 1.6 0.00013 20.2 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1347) 2OG-FeII_Oxy PF03171.15 ETO21992.1 - 4.1e-10 39.8 0.0 1e-09 38.5 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 ETO21992.1 - 4.9e-10 39.8 0.0 1.5e-09 38.3 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 ETO21992.1 - 0.00062 19.3 0.0 0.0019 17.7 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AAA_23 PF13476.1 ETO21993.1 - 0.11 12.8 16.9 0.13 12.5 11.7 1.2 1 0 0 1 1 1 0 AAA domain DDHD PF02862.12 ETO21993.1 - 0.28 10.9 11.5 0.42 10.3 8.0 1.2 1 0 0 1 1 1 0 DDHD domain BSMAP PF12280.3 ETO21993.1 - 0.33 10.7 6.8 0.42 10.4 4.7 1.2 1 0 0 1 1 1 0 Brain specific membrane anchored protein RNA_pol_3_Rpc31 PF11705.3 ETO21993.1 - 0.36 10.7 20.2 0.52 10.2 14.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Zip PF02535.17 ETO21993.1 - 0.45 9.4 1.7 0.47 9.4 1.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter GAGA_bind PF06217.7 ETO21993.1 - 1 9.2 12.0 1.3 8.8 8.3 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF1510 PF07423.6 ETO21993.1 - 1.7 7.9 21.7 2.1 7.6 15.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2413 PF10310.4 ETO21993.1 - 2 7.1 19.2 2.4 6.9 13.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Pox_Ag35 PF03286.9 ETO21993.1 - 4.5 6.7 19.6 6.7 6.1 13.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RR_TM4-6 PF06459.7 ETO21993.1 - 4.5 7.0 18.6 5.9 6.7 12.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.1 ETO21993.1 - 4.9 6.8 13.5 7.1 6.3 9.4 1.2 1 0 0 1 1 1 0 Protein Family FAM60A CT47 PF15623.1 ETO21993.1 - 6.4 6.4 18.8 7.8 6.1 13.0 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 Neur_chan_memb PF02932.11 ETO21993.1 - 7.6 6.3 11.9 11 5.8 8.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ycf1 PF05758.7 ETO21993.1 - 9.5 3.7 20.6 12 3.4 14.3 1.1 1 0 0 1 1 1 0 Ycf1 Arm PF00514.18 ETO21994.1 - 6.1e-05 22.6 0.2 0.018 14.8 0.0 3.7 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat DUF970 PF06153.6 ETO21994.1 - 0.088 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF970) HEAT_EZ PF13513.1 ETO21994.1 - 0.14 12.7 1.1 5.9 7.5 0.0 3.0 2 1 1 3 3 3 0 HEAT-like repeat Na_Ca_ex PF01699.19 ETO21996.1 - 1.8e-20 72.9 6.5 2.7e-20 72.3 4.1 1.6 1 1 1 2 2 2 1 Sodium/calcium exchanger protein Ssu72 PF04722.8 ETO21996.1 - 0.057 12.7 0.1 0.087 12.1 0.1 1.2 1 0 0 1 1 1 0 Ssu72-like protein DUF2951 PF11166.3 ETO21997.1 - 0.039 13.7 6.1 0.075 12.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) MIP-T3 PF10243.4 ETO21998.1 - 0.34 9.3 27.9 0.1 11.0 17.5 1.4 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 fn3 PF00041.16 ETO22000.1 - 0.00026 21.0 0.0 0.00088 19.3 0.0 2.0 1 1 0 1 1 1 1 Fibronectin type III domain Interfer-bind PF09294.5 ETO22000.1 - 0.00099 19.1 1.0 0.0023 17.9 0.1 2.1 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III ADIP PF11559.3 ETO22000.1 - 0.048 13.5 3.3 0.089 12.6 2.3 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.3 ETO22000.1 - 4.6 6.4 9.6 0.37 10.0 2.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) ATG13 PF10033.4 ETO22001.1 - 4.5e-06 26.2 1.0 0.001 18.5 0.1 2.6 2 1 0 2 2 2 2 Autophagy-related protein 13 DUF2890 PF11081.3 ETO22001.1 - 0.011 15.7 10.3 0.093 12.7 7.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Nop53 PF07767.6 ETO22001.1 - 0.019 13.9 12.2 0.032 13.2 8.5 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.7 ETO22001.1 - 0.029 12.3 10.9 0.038 11.9 7.5 1.2 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 ETO22001.1 - 0.042 12.3 14.3 0.057 11.9 9.9 1.1 1 0 0 1 1 1 0 Daxx Family Lin-8 PF03353.10 ETO22001.1 - 0.045 13.0 6.3 0.06 12.6 4.4 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF572 PF04502.8 ETO22001.1 - 0.096 11.8 13.6 0.16 11.2 9.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Spore_coat_CotO PF14153.1 ETO22001.1 - 0.56 9.6 14.9 1.3 8.4 10.3 1.6 1 0 0 1 1 1 0 Spore coat protein CotO CDC45 PF02724.9 ETO22001.1 - 0.57 8.1 10.9 0.76 7.7 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.7 ETO22001.1 - 0.73 9.6 12.1 1.3 8.8 8.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIF_alpha PF05793.7 ETO22001.1 - 1.4 7.2 16.8 2 6.6 11.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GAGA_bind PF06217.7 ETO22001.1 - 3.3 7.6 7.4 5 7.0 5.1 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Paf1 PF03985.8 ETO22001.1 - 4.2 5.9 16.4 6.3 5.4 11.3 1.2 1 0 0 1 1 1 0 Paf1 TRAP_alpha PF03896.11 ETO22001.1 - 4.4 6.2 11.5 8.3 5.3 7.9 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit TFIIA PF03153.8 ETO22002.1 - 0.34 10.7 19.9 0.58 10.0 13.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NB-ARC PF00931.17 ETO22003.1 - 0.0064 15.3 1.2 0.011 14.6 0.8 1.4 1 0 0 1 1 1 1 NB-ARC domain G-alpha PF00503.15 ETO22004.1 - 2e-12 46.5 3.4 2.1e-12 46.4 2.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit ABC_tran PF00005.22 ETO22004.1 - 0.0068 16.7 1.1 0.012 15.8 0.0 1.8 1 1 1 2 2 2 1 ABC transporter AAA_29 PF13555.1 ETO22004.1 - 0.014 14.8 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arf PF00025.16 ETO22004.1 - 0.037 13.2 0.2 0.065 12.4 0.1 1.5 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA_28 PF13521.1 ETO22004.1 - 0.056 13.4 0.4 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 ETO22004.1 - 0.072 13.0 0.1 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase SRPRB PF09439.5 ETO22004.1 - 0.18 10.9 0.1 0.18 10.9 0.1 2.0 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit DUF792 PF05632.6 ETO22004.1 - 0.98 8.7 5.2 0.28 10.4 1.7 1.4 2 0 0 2 2 2 0 Borrelia burgdorferi protein of unknown function (DUF792) Hydant_A_N PF05378.8 ETO22005.1 - 1.8e-27 95.9 0.0 3e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region zf-UBP PF02148.14 ETO22007.1 - 1.1e-10 41.4 2.5 2.4e-10 40.3 1.7 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH PF00443.24 ETO22007.1 - 3.6e-08 32.8 1.8 7.3e-08 31.8 0.2 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Draxin PF15550.1 ETO22007.1 - 0.0024 17.5 0.4 0.0032 17.1 0.3 1.1 1 0 0 1 1 1 1 Draxin zf-RING_3 PF14369.1 ETO22007.1 - 0.012 15.6 1.2 0.032 14.2 0.2 2.1 2 0 0 2 2 2 0 zinc-finger Vfa1 PF08432.5 ETO22007.1 - 0.097 12.6 6.7 0.13 12.3 4.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 eIF-3c_N PF05470.7 ETO22007.1 - 0.098 10.7 6.6 0.13 10.3 4.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DDHD PF02862.12 ETO22007.1 - 0.13 12.0 1.9 0.17 11.6 1.3 1.1 1 0 0 1 1 1 0 DDHD domain DUF2201_N PF13203.1 ETO22007.1 - 0.21 10.7 3.1 0.28 10.2 2.1 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain UPF1_Zn_bind PF09416.5 ETO22007.1 - 0.44 10.1 2.8 1.6 8.2 1.8 2.0 1 1 1 2 2 2 0 RNA helicase (UPF2 interacting domain) VitD-bind_III PF09164.5 ETO22007.1 - 0.5 10.0 3.0 0.3 10.7 0.2 2.1 2 0 0 2 2 2 0 Vitamin D binding protein, domain III zf-LYAR PF08790.6 ETO22007.1 - 1.7 8.3 5.1 0.47 10.2 0.9 2.1 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Lar_restr_allev PF14354.1 ETO22007.1 - 4.2 7.7 6.8 20 5.5 1.4 3.1 2 1 1 3 3 3 0 Restriction alleviation protein Lar FH2 PF02181.18 ETO22008.1 - 5.4e-28 97.9 5.5 7e-28 97.5 3.7 1.2 1 1 0 1 1 1 1 Formin Homology 2 Domain DUF992 PF06186.6 ETO22009.1 - 6.2 6.1 9.4 9.1 5.6 4.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF992) DDHD PF02862.12 ETO22010.1 - 2.4 7.9 9.3 2.4 7.8 2.3 2.2 2 0 0 2 2 2 0 DDHD domain CDC45 PF02724.9 ETO22010.1 - 2.6 5.9 20.5 0.047 11.7 8.5 1.9 2 0 0 2 2 2 0 CDC45-like protein EpuA PF11772.3 ETO22012.1 - 0.037 13.4 1.5 0.076 12.4 1.1 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta DUF4307 PF14155.1 ETO22012.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) Lipase_GDSL_2 PF13472.1 ETO22013.1 - 3.7e-07 30.4 0.0 6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CUB PF00431.15 ETO22013.1 - 0.062 13.3 0.2 0.17 11.9 0.2 1.8 1 0 0 1 1 1 0 CUB domain IBR PF01485.16 ETO22014.1 - 1.6e-06 27.8 3.9 1.6e-06 27.8 2.7 6.9 4 3 2 6 6 6 1 IBR domain zf-RING_2 PF13639.1 ETO22014.1 - 2.7e-05 23.8 7.0 2.7e-05 23.8 4.8 5.5 4 2 1 5 5 5 1 Ring finger domain zf-C3HC4 PF00097.20 ETO22014.1 - 2.8e-05 23.6 5.2 2.8e-05 23.6 3.6 4.9 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO22014.1 - 0.00092 19.1 7.7 0.00092 19.1 5.3 5.3 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO22014.1 - 0.0037 16.9 7.7 0.0037 16.9 5.3 5.3 5 2 0 5 5 5 2 zinc-RING finger domain Spy1 PF11357.3 ETO22015.1 - 0.42 10.7 4.2 0.15 12.1 0.3 2.0 2 0 0 2 2 2 0 Cell cycle regulatory protein Casc1 PF12366.3 ETO22015.1 - 2 7.8 19.5 1.9 7.9 3.6 2.4 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 Hydrolase PF00702.21 ETO22016.1 - 2.2e-09 38.0 0.1 2.9e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETO22016.1 - 5.9e-06 26.5 0.0 6.8e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1216 PF06746.6 ETO22016.1 - 0.0092 15.7 1.3 0.018 14.7 0.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1216) AhpC-TSA PF00578.16 ETO22016.1 - 0.044 13.4 0.0 0.18 11.4 0.0 1.9 2 1 0 2 2 2 0 AhpC/TSA family N6-adenineMlase PF10237.4 ETO22016.1 - 0.054 13.1 0.7 0.18 11.4 0.1 2.0 1 1 0 2 2 2 0 Probable N6-adenine methyltransferase Menin PF05053.8 ETO22016.1 - 0.061 11.4 3.0 0.06 11.5 2.0 1.1 1 0 0 1 1 1 0 Menin NUDIX_2 PF13869.1 ETO22016.1 - 0.12 11.7 0.9 0.24 10.7 0.6 1.5 1 0 0 1 1 1 0 Nucleotide hydrolase Pex16 PF08610.5 ETO22016.1 - 0.28 10.1 3.9 0.35 9.8 2.7 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF1510 PF07423.6 ETO22016.1 - 0.3 10.4 9.7 0.41 9.9 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SPX PF03105.14 ETO22016.1 - 0.34 10.6 13.5 2 8.1 9.4 1.9 1 1 0 1 1 1 0 SPX domain RP-C_C PF11800.3 ETO22016.1 - 0.51 10.0 5.1 0.7 9.5 3.5 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region XAP5 PF04921.9 ETO22016.1 - 0.78 9.2 7.3 0.92 9.0 5.1 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator PH_10 PF15411.1 ETO22016.1 - 3.5 7.8 7.1 3.2 7.9 4.1 1.5 1 1 0 1 1 1 0 Pleckstrin homology domain Hydrolase_3 PF08282.7 ETO22016.1 - 4 6.9 13.0 2.8 7.4 0.1 2.4 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF3884 PF13024.1 ETO22017.1 - 0.18 11.2 0.9 14 5.1 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3884) AAA_23 PF13476.1 ETO22017.1 - 9.7 6.4 10.7 13 5.9 7.4 1.5 1 1 0 1 1 1 0 AAA domain Mucin PF01456.12 ETO22018.1 - 0.27 10.9 13.7 5.9 6.6 0.0 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein U79_P34 PF03064.11 ETO22018.1 - 1.2 8.6 9.1 8.6 5.7 0.1 2.2 2 0 0 2 2 2 0 HSV U79 / HCMV P34 TraH_2 PF06871.6 ETO22018.1 - 4 6.8 6.2 0.39 10.1 0.6 1.9 2 0 0 2 2 2 0 TraH_2 FAM60A PF15396.1 ETO22018.1 - 4.4 7.0 8.1 1.3 8.6 1.1 2.2 2 0 0 2 2 2 0 Protein Family FAM60A UCH PF00443.24 ETO22019.1 - 4.6e-41 140.7 0.1 6.8e-41 140.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO22019.1 - 3.9e-20 72.4 0.0 1.2e-18 67.6 0.0 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2072 PF09845.4 ETO22019.1 - 0.07 13.0 0.1 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) AAA_23 PF13476.1 ETO22020.1 - 1e-16 61.8 14.1 1e-16 61.8 9.8 4.6 2 1 2 4 4 4 1 AAA domain SMC_N PF02463.14 ETO22020.1 - 1.6e-10 40.5 7.6 2.9e-10 39.7 4.3 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 ETO22020.1 - 0.0024 17.3 0.0 0.0047 16.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 ETO22020.1 - 0.24 9.7 0.0 0.24 9.7 0.0 4.2 1 1 2 4 4 4 0 AAA domain Cullin PF00888.17 ETO22021.1 - 7.5e-17 61.0 5.4 8.9e-17 60.8 3.7 1.1 1 0 0 1 1 1 1 Cullin family Zn_Tnp_IS1595 PF12760.2 ETO22022.1 - 1.1e-07 31.5 8.2 1.6e-07 30.9 5.7 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DDE_Tnp_IS1595 PF12762.2 ETO22022.1 - 2.9e-06 27.2 0.1 4.5e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 ISXO2-like transposase domain Sigma70_r4_2 PF08281.7 ETO22022.1 - 0.0014 18.0 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.1 ETO22022.1 - 0.061 12.5 0.1 0.095 11.8 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 zf-H2C2_2 PF13465.1 ETO22022.1 - 0.14 12.5 4.0 0.14 12.5 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double domain FeoC PF09012.5 ETO22022.1 - 0.75 9.5 0.1 0.75 9.5 0.1 2.9 2 1 0 2 2 2 0 FeoC like transcriptional regulator BMFP PF04380.8 ETO22023.1 - 2.3e-15 56.4 0.2 5.4e-15 55.3 0.2 1.6 1 0 0 1 1 1 1 Membrane fusogenic activity DDHD PF02862.12 ETO22023.1 - 0.013 15.3 1.1 0.015 15.0 0.8 1.2 1 0 0 1 1 1 0 DDHD domain HC2 PF07382.6 ETO22023.1 - 0.12 12.1 31.1 0.15 11.9 21.3 1.4 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Peptidase_S49_N PF08496.5 ETO22023.1 - 0.52 10.0 6.3 0.75 9.5 4.4 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal N6_Mtase PF02384.11 ETO22024.1 - 2.3e-30 105.7 0.1 2.3e-30 105.7 0.1 3.4 3 1 1 4 4 4 1 N-6 DNA Methylase Methylase_S PF01420.14 ETO22024.1 - 1.4e-11 44.6 34.1 3.4e-09 36.9 8.4 4.5 3 2 0 3 3 3 2 Type I restriction modification DNA specificity domain UPF0020 PF01170.13 ETO22024.1 - 1.6e-11 44.1 0.1 5.8e-11 42.2 0.0 1.9 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 HSDR_N_2 PF13588.1 ETO22024.1 - 6.1e-09 35.6 0.4 6.1e-09 35.6 0.3 3.2 4 0 0 4 4 4 1 Type I restriction enzyme R protein N terminus (HSDR_N) Methyltransf_26 PF13659.1 ETO22024.1 - 3.8e-05 23.7 0.0 7.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETO22024.1 - 0.021 14.1 0.6 0.086 12.2 0.0 2.3 3 0 0 3 3 3 0 Methyltransferase small domain VRR_NUC PF08774.6 ETO22024.1 - 0.025 14.5 0.0 0.077 13.0 0.0 1.8 1 0 0 1 1 1 0 VRR-NUC domain Gp58 PF07902.6 ETO22025.1 - 0.047 11.9 8.5 0.05 11.8 5.9 1.0 1 0 0 1 1 1 0 gp58-like protein DUF3256 PF11644.3 ETO22025.1 - 0.069 12.6 1.6 0.096 12.1 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3256) Atg14 PF10186.4 ETO22025.1 - 0.28 10.0 26.0 0.36 9.7 18.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PhoQ_Sensor PF08918.5 ETO22025.1 - 1.7 8.1 8.4 2.7 7.4 5.6 1.5 1 1 0 1 1 1 0 PhoQ Sensor DASH_Dad3 PF08656.5 ETO22025.1 - 2.1 8.1 7.7 0.6 9.8 2.9 2.0 2 1 0 2 2 2 0 DASH complex subunit Dad3 DUF2317 PF10079.4 ETO22025.1 - 4.8 5.6 17.4 1.3 7.5 10.1 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) IncA PF04156.9 ETO22025.1 - 8.3 5.9 20.6 9.8 5.7 14.3 1.1 1 0 0 1 1 1 0 IncA protein UAA PF08449.6 ETO22026.1 - 3.3e-36 124.7 13.5 4.2e-36 124.4 9.4 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 ETO22026.1 - 2.2e-11 43.6 13.2 2.1e-10 40.4 2.9 2.8 3 0 0 3 3 3 2 Triose-phosphate Transporter family EamA PF00892.15 ETO22026.1 - 3.6e-05 23.8 7.4 0.014 15.4 0.2 2.4 2 0 0 2 2 2 2 EamA-like transporter family DUF606 PF04657.8 ETO22026.1 - 0.052 13.6 6.1 0.032 14.3 2.7 1.8 1 1 1 2 2 2 0 Protein of unknown function, DUF606 Sigma70_ner PF04546.8 ETO22027.1 - 0.02 14.5 4.8 0.023 14.3 3.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2777 PF10949.3 ETO22027.1 - 0.066 12.8 0.2 0.08 12.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2777) DUF506 PF04720.7 ETO22027.1 - 0.069 12.7 1.6 0.079 12.5 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Nop14 PF04147.7 ETO22027.1 - 0.46 8.3 7.0 0.39 8.5 4.9 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 ETO22027.1 - 0.51 8.7 7.1 0.52 8.7 4.9 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 ETO22027.1 - 0.82 7.6 6.2 0.88 7.5 4.3 1.0 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.6 ETO22027.1 - 0.96 9.2 8.4 1.4 8.7 5.9 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal SGT1 PF07093.6 ETO22027.1 - 1.4 7.1 8.7 1.4 7.2 6.0 1.0 1 0 0 1 1 1 0 SGT1 protein CENP-B_dimeris PF09026.5 ETO22027.1 - 3.9 7.7 12.0 6 7.1 8.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SPX PF03105.14 ETO22030.1 - 0.88 9.2 40.9 1.2 8.9 28.4 1.1 1 0 0 1 1 1 0 SPX domain Peptidase_S64 PF08192.6 ETO22030.1 - 3.6 5.8 34.4 4.1 5.6 23.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 FUN14 PF04930.10 ETO22031.1 - 1.2e-11 44.7 1.9 2.6e-11 43.6 1.3 1.6 1 0 0 1 1 1 1 FUN14 family SPC12 PF06645.8 ETO22031.1 - 0.13 12.1 0.1 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF1626 PF07788.6 ETO22032.1 - 0.0048 16.6 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1626) TPT PF03151.11 ETO22032.1 - 0.033 13.8 0.0 0.065 12.8 0.0 1.5 1 0 0 1 1 1 0 Triose-phosphate Transporter family Ank_2 PF12796.2 ETO22032.1 - 0.043 14.1 0.0 0.81 10.0 0.0 2.6 1 1 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO22032.1 - 0.076 13.2 0.0 1.2 9.5 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeat cNMP_binding PF00027.24 ETO22033.1 - 2.6e-38 129.7 0.0 2.6e-19 68.8 0.0 3.6 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain Trypan_PARP PF05887.6 ETO22034.1 - 1.1 9.0 13.0 3 7.6 9.0 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Transket_pyr PF02779.19 ETO22037.1 - 4.4e-59 198.9 0.0 1.1e-58 197.6 0.0 1.7 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 ETO22037.1 - 2.4e-53 180.8 0.2 2.3e-48 164.4 0.1 2.2 2 0 0 2 2 2 2 Dehydrogenase E1 component UCH PF00443.24 ETO22039.1 - 2.2e-20 72.9 0.7 2.6e-20 72.6 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO22039.1 - 1.7e-11 44.1 1.2 2.1e-11 43.8 0.8 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase NapB PF03892.9 ETO22039.1 - 0.15 11.7 2.5 0.29 10.8 1.7 1.6 1 1 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) UCH PF00443.24 ETO22040.1 - 2.3e-05 23.6 7.3 0.0021 17.2 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Phage_P2_GpU PF06995.6 ETO22040.1 - 0.047 13.0 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 Phage P2 GpU ANAPC15 PF15243.1 ETO22040.1 - 0.1 12.7 1.6 11 6.1 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Rhodanese PF00581.15 ETO22041.1 - 5.6e-07 29.9 0.1 2.6e-06 27.7 0.0 2.1 2 1 0 2 2 2 1 Rhodanese-like domain SART-1 PF03343.8 ETO22041.1 - 0.0003 19.3 7.3 0.00031 19.2 5.1 1.2 1 0 0 1 1 1 1 SART-1 family XAP5 PF04921.9 ETO22041.1 - 0.068 12.7 7.1 0.1 12.1 4.9 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator Raftlin PF15250.1 ETO22041.1 - 0.088 11.3 5.7 0.12 10.9 3.9 1.1 1 0 0 1 1 1 0 Raftlin CobT PF06213.7 ETO22041.1 - 0.26 10.3 7.9 0.39 9.8 5.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT AF-4 PF05110.8 ETO22041.1 - 0.54 8.0 13.7 0.67 7.7 9.5 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Tetraspannin PF00335.15 ETO22041.1 - 1.4 8.1 3.4 1.7 7.8 2.3 1.2 1 0 0 1 1 1 0 Tetraspanin family NRDE-2 PF08424.5 ETO22041.1 - 1.4 7.6 8.5 2.4 6.9 5.9 1.3 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Macoilin PF09726.4 ETO22041.1 - 5.1 5.2 10.1 5.7 5.0 7.0 1.2 1 0 0 1 1 1 0 Transmembrane protein RabGAP-TBC PF00566.13 ETO22042.1 - 1.1e-32 113.3 8.8 9.9e-31 106.8 4.1 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain rpo132 PF12415.3 ETO22042.1 - 0.00046 19.0 0.1 0.032 13.1 0.1 2.5 2 0 0 2 2 2 2 Poxvirus DNA dependent RNA polymerase BTB PF00651.26 ETO22044.1 - 0.014 15.4 0.3 0.024 14.6 0.0 1.6 2 0 0 2 2 2 0 BTB/POZ domain Plasmodium_Vir PF05795.6 ETO22044.1 - 0.014 14.6 0.1 0.014 14.6 0.1 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein BCLP PF12304.3 ETO22044.1 - 0.015 14.7 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Beta-casein like protein UPF0542 PF15086.1 ETO22044.1 - 0.058 13.1 0.7 0.086 12.5 0.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 DUF92 PF01940.11 ETO22044.1 - 0.073 12.2 0.2 0.099 11.7 0.1 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF92 gpUL132 PF11359.3 ETO22044.1 - 0.085 12.1 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 USP7_ICP0_bdg PF12436.3 ETO22045.1 - 2.6e-20 72.7 0.2 5.9e-20 71.5 0.1 1.6 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 Cation_efflux PF01545.16 ETO22046.1 - 0.0081 15.2 5.1 0.18 10.8 0.0 3.1 3 1 0 3 3 3 2 Cation efflux family FtsX PF02687.16 ETO22046.1 - 1.1 9.0 11.7 0.41 10.4 0.2 4.3 5 0 0 5 5 5 0 FtsX-like permease family DUF912 PF06024.7 ETO22046.1 - 3.7 7.6 7.7 4.8 7.2 0.4 3.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Mucin PF01456.12 ETO22047.1 - 0.19 11.4 15.9 0.36 10.6 11.0 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein FlaC_arch PF05377.6 ETO22048.1 - 0.04 13.8 0.3 0.55 10.1 0.0 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FlxA PF14282.1 ETO22048.1 - 0.95 9.4 9.9 0.029 14.2 1.8 2.1 2 0 0 2 2 2 0 FlxA-like protein HR1 PF02185.11 ETO22048.1 - 1.9 8.2 8.5 0.17 11.6 1.0 2.5 2 1 0 2 2 2 0 Hr1 repeat Pirin PF02678.11 ETO22049.1 - 1.9e-16 59.8 0.2 5.8e-10 38.9 0.1 2.7 2 0 0 2 2 2 2 Pirin Pirin_C PF05726.8 ETO22049.1 - 3.9e-08 33.3 0.0 9e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Pirin C-terminal cupin domain Abhydrolase_3 PF07859.8 ETO22050.1 - 5.1e-33 114.4 0.3 1.3e-31 109.8 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 ETO22050.1 - 8.6e-09 34.5 0.0 2.1e-06 26.6 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 ETO22050.1 - 0.0076 16.0 0.0 0.017 14.8 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.13 ETO22050.1 - 0.026 13.8 0.5 0.15 11.2 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Thioesterase PF00975.15 ETO22050.1 - 0.097 12.8 0.2 0.25 11.5 0.0 1.7 2 0 0 2 2 2 0 Thioesterase domain DUF506 PF04720.7 ETO22050.1 - 5.2 6.6 12.2 0.96 9.0 3.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF506) ABC2_membrane_3 PF12698.2 ETO22051.1 - 0.027 13.5 0.6 0.037 13.0 0.4 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4423 PF14394.1 ETO22051.1 - 0.087 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) tRNA-synt_1 PF00133.17 ETO22052.1 - 1.3e-91 307.4 0.1 2.3e-80 270.3 0.1 2.0 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 ETO22052.1 - 1.1e-08 34.1 0.1 0.00021 20.0 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 ETO22053.1 - 5.9e-51 173.1 1.7 6.4e-51 173.0 1.2 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) DUF1945 PF09178.5 ETO22053.1 - 0.0067 16.2 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1945) DUF2839 PF10999.3 ETO22054.1 - 0.011 15.7 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2839) DUF4661 PF15576.1 ETO22054.1 - 0.083 12.5 0.4 0.13 11.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Laminin_G_3 PF13385.1 ETO22054.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily ART PF01129.13 ETO22055.1 - 8.1e-05 21.8 0.3 0.00016 20.9 0.2 1.5 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase TPR_12 PF13424.1 ETO22057.1 - 7.2e-50 166.8 10.3 7.1e-17 61.1 0.3 4.6 3 2 2 5 5 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO22057.1 - 4.4e-34 113.5 9.1 1.3e-07 30.8 0.0 6.5 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETO22057.1 - 2.3e-30 102.9 31.9 1.1e-07 31.1 0.1 6.9 6 1 1 7 7 6 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETO22057.1 - 1.7e-28 97.6 0.0 3.3e-08 33.2 0.0 6.2 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO22057.1 - 1.6e-26 91.7 21.0 6.8e-09 35.2 0.2 4.6 2 2 2 4 4 4 4 TPR repeat TPR_2 PF07719.12 ETO22057.1 - 1.2e-24 84.2 22.4 1.2e-05 24.8 1.5 6.7 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 ETO22057.1 - 2e-20 70.9 36.6 1.1e-05 24.8 0.2 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 ETO22057.1 - 1.9e-14 52.5 7.4 0.0053 16.8 0.3 6.4 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO22057.1 - 7.8e-09 35.4 4.1 0.042 14.3 0.4 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO22057.1 - 9.6e-07 29.3 0.7 0.063 13.9 0.0 4.5 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO22057.1 - 3.8e-06 27.0 0.0 7.5 7.4 0.0 5.5 5 1 1 6 6 5 1 Tetratricopeptide repeat DUF896 PF05979.7 ETO22057.1 - 0.0055 16.2 0.1 0.025 14.1 0.1 2.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF896) MIT PF04212.13 ETO22057.1 - 0.0087 15.9 20.2 0.78 9.6 0.1 5.3 4 1 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 ETO22057.1 - 0.048 13.4 22.7 0.55 10.0 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat Apc3 PF12895.2 ETO22057.1 - 0.066 13.3 16.1 0.81 9.8 3.2 4.7 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO22057.1 - 0.068 13.5 4.0 27 5.2 0.0 4.4 1 1 4 5 5 5 0 Tetratricopeptide repeat PPR PF01535.15 ETO22057.1 - 0.16 12.0 13.5 7.1 6.8 0.1 6.8 7 1 1 8 8 7 0 PPR repeat FATC PF02260.15 ETO22057.1 - 5.7 6.4 6.2 19 4.7 0.0 3.5 4 0 0 4 4 3 0 FATC domain EamA PF00892.15 ETO22058.1 - 2.6e-21 75.9 29.9 4e-12 46.2 9.6 3.2 2 1 1 3 3 3 3 EamA-like transporter family SpoIIIAC PF06686.6 ETO22058.1 - 0.11 12.2 4.7 0.14 11.9 0.4 3.1 2 0 0 2 2 2 0 Stage III sporulation protein AC/AD protein family TraQ PF09679.5 ETO22058.1 - 1 9.3 4.5 7.9 6.4 0.2 3.0 3 0 0 3 3 3 0 Type-F conjugative transfer system pilin chaperone (TraQ) EmrE PF13536.1 ETO22058.1 - 4.6 7.4 22.2 0.68 10.1 5.2 3.7 2 2 0 3 3 3 0 Multidrug resistance efflux transporter CENP-B_dimeris PF09026.5 ETO22060.1 - 0.0058 16.8 6.7 0.0058 16.8 4.7 3.7 2 1 1 3 3 3 1 Centromere protein B dimerisation domain YqhR PF11085.3 ETO22060.1 - 0.14 11.7 0.1 0.14 11.7 0.1 2.4 3 0 0 3 3 3 0 Conserved membrane protein YqhR Plasmodium_Vir PF05795.6 ETO22060.1 - 0.8 8.8 26.7 0.084 12.0 14.3 2.2 2 0 0 2 2 2 0 Plasmodium vivax Vir protein eIF-3c_N PF05470.7 ETO22060.1 - 0.96 7.4 30.8 0.12 10.4 2.5 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CobT PF06213.7 ETO22060.1 - 4.2 6.4 40.8 0.76 8.8 12.5 2.4 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Glyco_hydro_47 PF01532.15 ETO22061.1 - 2.1e-13 49.7 0.8 5.5e-09 35.2 0.1 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 47 DUF4283 PF14111.1 ETO22061.1 - 0.1 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4283) DUF2457 PF10446.4 ETO22061.1 - 0.34 9.6 12.0 0.52 8.9 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) ERF PF04404.7 ETO22061.1 - 0.88 9.0 6.3 32 4.0 4.8 2.4 2 0 0 2 2 2 0 ERF superfamily DUF605 PF04652.11 ETO22062.1 - 0.12 11.7 31.6 0.17 11.2 21.9 1.2 1 0 0 1 1 1 0 Vta1 like TPR_12 PF13424.1 ETO22064.1 - 7.7e-120 391.0 49.3 5.4e-24 83.9 0.1 5.9 1 1 6 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.1 ETO22064.1 - 9.9e-61 200.0 2.6 1.1e-08 34.7 0.0 8.4 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_11 PF13414.1 ETO22064.1 - 8e-57 188.7 58.6 1.9e-16 59.4 0.5 6.4 3 2 5 8 8 8 7 TPR repeat TPR_1 PF00515.23 ETO22064.1 - 6.9e-56 183.7 44.1 4e-09 35.6 1.2 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_7 PF13176.1 ETO22064.1 - 1e-52 171.8 14.3 8.6e-07 28.3 0.1 8.6 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_8 PF13181.1 ETO22064.1 - 4.1e-43 141.9 38.4 1.4e-06 27.6 0.9 9.6 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 ETO22064.1 - 7.1e-40 131.7 36.5 2.2e-06 27.1 0.5 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_17 PF13431.1 ETO22064.1 - 2.8e-27 92.5 9.4 0.0045 17.0 0.0 9.1 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_14 PF13428.1 ETO22064.1 - 4.6e-23 79.5 0.3 0.19 12.4 0.0 9.0 7 2 2 9 9 9 5 Tetratricopeptide repeat TPR_6 PF13174.1 ETO22064.1 - 2.7e-15 55.6 6.8 0.26 11.8 0.0 8.4 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO22064.1 - 2e-13 50.6 9.4 0.015 15.9 0.0 6.3 3 2 4 7 7 6 6 Tetratricopeptide repeat TPR_19 PF14559.1 ETO22064.1 - 3e-11 43.4 4.2 0.007 16.6 0.0 5.3 4 1 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO22064.1 - 1.2e-07 31.7 21.0 0.00057 19.9 0.6 5.3 1 1 6 7 7 7 6 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 ETO22064.1 - 1.5e-07 31.2 24.8 0.014 15.2 0.0 8.0 7 1 1 8 8 8 3 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 ETO22064.1 - 6.5e-07 29.0 17.1 0.0091 15.7 0.4 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO22064.1 - 1.3e-05 24.3 4.8 6.5 6.0 0.0 6.9 8 0 0 8 8 8 1 SHNi-TPR TPR_4 PF07721.9 ETO22064.1 - 0.0033 17.7 0.0 51 4.7 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat PPR PF01535.15 ETO22064.1 - 0.011 15.6 10.2 6.3 7.0 0.0 6.5 7 0 0 7 7 7 0 PPR repeat TPR_5 PF12688.2 ETO22064.1 - 0.018 15.0 1.6 4.8 7.2 0.0 4.2 3 1 1 5 5 4 0 Tetratrico peptide repeat ING PF12998.2 ETO22065.1 - 0.0016 18.6 2.3 0.0032 17.6 1.6 1.6 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding CoaE PF01121.15 ETO22065.1 - 0.018 14.4 0.9 0.022 14.1 0.6 1.2 1 0 0 1 1 1 0 Dephospho-CoA kinase Hat1_N PF10394.4 ETO22065.1 - 0.026 14.6 0.3 0.03 14.3 0.2 1.2 1 0 0 1 1 1 0 Histone acetyl transferase HAT1 N-terminus DUF2895 PF11444.3 ETO22065.1 - 0.11 11.6 0.6 0.24 10.5 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2895) Acetate_kinase PF00871.12 ETO22065.1 - 0.16 10.4 1.8 0.2 10.1 1.3 1.1 1 0 0 1 1 1 0 Acetokinase family Fucose_iso_N2 PF07882.7 ETO22065.1 - 0.18 11.4 0.9 0.24 11.0 0.6 1.2 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain OmpH PF03938.9 ETO22065.1 - 0.28 11.1 3.7 0.35 10.7 2.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) NUMOD3 PF07460.6 ETO22065.1 - 0.35 10.8 0.2 0.35 10.8 0.1 2.2 3 0 0 3 3 3 0 NUMOD3 motif (2 copies) YlqD PF11068.3 ETO22065.1 - 1 9.4 8.4 0.73 9.8 4.5 1.9 1 1 1 2 2 2 0 YlqD protein DUF1664 PF07889.7 ETO22065.1 - 1.3 8.8 6.1 1.2 8.9 3.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) IncA PF04156.9 ETO22065.1 - 1.8 8.1 10.3 4.3 6.8 7.1 1.6 1 1 0 1 1 1 0 IncA protein Fzo_mitofusin PF04799.8 ETO22065.1 - 3.9 6.8 8.1 4.4 6.6 4.0 1.9 1 1 1 2 2 2 0 fzo-like conserved region CDC45 PF02724.9 ETO22066.1 - 0.0022 16.0 18.5 0.003 15.6 12.8 1.2 1 0 0 1 1 1 1 CDC45-like protein Daxx PF03344.10 ETO22066.1 - 0.0032 16.0 17.5 0.0037 15.8 12.1 1.1 1 0 0 1 1 1 1 Daxx Family U79_P34 PF03064.11 ETO22066.1 - 0.014 14.8 25.6 0.026 14.0 17.8 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 NOA36 PF06524.7 ETO22066.1 - 0.28 10.3 18.5 0.56 9.4 12.8 1.4 1 0 0 1 1 1 0 NOA36 protein VGLL4 PF15245.1 ETO22066.1 - 0.59 9.9 18.0 1.1 9.1 12.2 1.7 1 1 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 Astro_capsid PF03115.9 ETO22066.1 - 1.1 7.4 10.5 1.5 7.0 7.3 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF1510 PF07423.6 ETO22066.1 - 2.7 7.3 26.3 5.3 6.3 18.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Arm PF00514.18 ETO22067.1 - 0.056 13.2 0.3 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Methyltransf_31 PF13847.1 ETO22068.1 - 0.088 12.3 0.0 12 5.4 0.0 2.7 1 1 1 2 2 2 0 Methyltransferase domain Ank PF00023.25 ETO22069.1 - 1.9e-19 68.4 0.1 3.2e-10 39.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 ETO22069.1 - 2.2e-17 63.1 0.0 4.4e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO22069.1 - 5.2e-15 55.4 0.2 9.5e-12 45.1 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO22069.1 - 8.6e-15 54.4 0.2 1.1e-10 41.3 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO22069.1 - 1.8e-14 52.3 0.0 1.8e-07 30.6 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat RNA_pol_Rpb1_1 PF04997.7 ETO22072.1 - 2.6 7.2 9.3 1.4 8.1 5.2 1.5 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 1 FH2 PF02181.18 ETO22073.1 - 2.5e-27 95.7 0.2 2.8e-27 95.5 0.1 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain DUF3989 PF13150.1 ETO22073.1 - 0.031 13.7 0.0 0.059 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) DUF1371 PF07115.6 ETO22073.1 - 0.074 13.2 0.3 0.096 12.8 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1371) DUF843 PF05814.6 ETO22074.1 - 0.12 12.1 1.5 0.69 9.7 0.2 2.1 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) zf-RanBP PF00641.13 ETO22075.1 - 0.0008 18.4 6.7 0.0018 17.3 4.6 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-ribbon_3 PF13248.1 ETO22075.1 - 0.018 14.2 0.9 0.051 12.7 0.6 1.8 1 0 0 1 1 1 0 zinc-ribbon domain Enterotoxin_b PF01376.13 ETO22075.1 - 0.29 11.0 3.7 0.25 11.2 0.4 2.3 1 1 1 2 2 2 0 Heat-labile enterotoxin beta chain RNA_pol_Rpb1_7 PF04990.7 ETO22075.1 - 0.82 9.3 8.4 1.1 9.0 5.2 1.6 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 7 Spt5_N PF11942.3 ETO22075.1 - 4.2 8.0 12.8 0.31 11.6 4.6 2.3 2 1 1 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal V_ATPase_I PF01496.14 ETO22075.1 - 7.9 4.1 11.5 10 3.8 8.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ERM PF00769.14 ETO22076.1 - 0.00028 20.5 9.6 0.00032 20.3 6.6 1.0 1 0 0 1 1 1 1 Ezrin/radixin/moesin family APG6 PF04111.7 ETO22076.1 - 0.00072 18.7 11.0 0.00087 18.4 7.6 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 HOOK PF05622.7 ETO22076.1 - 0.0012 16.7 4.8 0.0013 16.6 3.3 1.1 1 0 0 1 1 1 1 HOOK protein Filament PF00038.16 ETO22076.1 - 0.0019 17.7 12.3 0.0026 17.2 8.5 1.2 1 0 0 1 1 1 1 Intermediate filament protein HAUS-augmin3 PF14932.1 ETO22076.1 - 0.0023 17.1 8.8 0.0029 16.8 6.1 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 V_ATPase_I PF01496.14 ETO22076.1 - 0.0024 15.7 7.8 0.0031 15.4 5.4 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Spc7 PF08317.6 ETO22076.1 - 0.0047 15.6 11.9 0.0064 15.1 8.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Dor1 PF04124.7 ETO22076.1 - 0.011 14.2 10.1 0.014 13.9 7.0 1.1 1 0 0 1 1 1 0 Dor1-like family Rop-like PF05082.8 ETO22076.1 - 0.014 14.8 2.7 0.38 10.2 0.2 2.4 2 0 0 2 2 2 0 Rop-like DNA_pol_viral_N PF00242.12 ETO22076.1 - 0.021 13.8 1.0 0.027 13.5 0.7 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF342 PF03961.8 ETO22076.1 - 0.028 12.8 10.5 0.032 12.6 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TraC_F_IV PF11130.3 ETO22076.1 - 0.048 13.0 0.5 2.9 7.2 0.1 2.3 2 1 0 2 2 2 0 F pilus assembly Type-IV secretion system for plasmid transfer Reo_sigmaC PF04582.7 ETO22076.1 - 0.05 12.7 0.4 0.072 12.2 0.3 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF4472 PF14739.1 ETO22076.1 - 0.086 13.2 10.2 0.13 12.6 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) ADIP PF11559.3 ETO22076.1 - 0.12 12.3 16.8 0.19 11.6 11.7 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Prefoldin_2 PF01920.15 ETO22076.1 - 0.16 11.7 16.9 0.09 12.5 2.5 2.6 1 1 2 3 3 3 0 Prefoldin subunit EHN PF06441.7 ETO22076.1 - 0.17 11.7 4.1 0.39 10.6 2.8 1.7 1 1 0 1 1 1 0 Epoxide hydrolase N terminus DUF3584 PF12128.3 ETO22076.1 - 0.18 9.0 11.7 0.25 8.6 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) YlqD PF11068.3 ETO22076.1 - 0.18 11.8 12.2 0.43 10.6 8.5 1.6 1 1 0 1 1 1 0 YlqD protein HCMV_UL139 PF12507.3 ETO22076.1 - 0.2 11.8 6.7 0.48 10.6 3.2 2.0 1 1 1 2 2 2 0 Human Cytomegalovirus UL139 protein FlxA PF14282.1 ETO22076.1 - 0.21 11.5 14.0 0.31 11.0 9.7 1.3 1 0 0 1 1 1 0 FlxA-like protein Prefoldin PF02996.12 ETO22076.1 - 0.21 11.2 12.1 0.6 9.7 2.7 2.4 1 1 1 2 2 2 0 Prefoldin subunit Tup_N PF08581.5 ETO22076.1 - 0.33 11.1 9.8 0.34 11.1 1.2 2.6 2 1 0 2 2 2 0 Tup N-terminal Tropomyosin_1 PF12718.2 ETO22076.1 - 0.41 10.4 17.5 0.82 9.5 12.1 1.4 1 1 0 1 1 1 0 Tropomyosin like GAS PF13851.1 ETO22076.1 - 0.5 9.5 19.0 0.4 9.8 4.2 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Mnd1 PF03962.10 ETO22076.1 - 0.61 9.7 16.1 0.78 9.3 10.9 1.4 1 1 0 1 1 1 0 Mnd1 family TMF_DNA_bd PF12329.3 ETO22076.1 - 0.71 9.7 20.1 0.61 9.9 7.4 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 ETO22076.1 - 0.77 9.3 13.7 1.2 8.7 2.5 2.0 1 1 1 2 2 2 0 IncA protein DUF641 PF04859.7 ETO22076.1 - 0.91 9.2 12.5 2.9 7.6 7.7 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF4164 PF13747.1 ETO22076.1 - 1.2 9.3 8.2 0.91 9.6 4.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) GBP_C PF02841.9 ETO22076.1 - 1.2 8.2 15.0 1.6 7.8 10.4 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Ax_dynein_light PF10211.4 ETO22076.1 - 1.4 8.7 18.8 0.18 11.6 8.5 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain DUF4140 PF13600.1 ETO22076.1 - 1.6 9.2 5.5 0.37 11.2 0.5 2.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4337 PF14235.1 ETO22076.1 - 1.6 8.5 13.0 1.6 8.5 3.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) DivIC PF04977.10 ETO22076.1 - 1.7 8.1 13.4 0.4 10.2 2.4 2.6 1 1 0 2 2 2 0 Septum formation initiator bZIP_1 PF00170.16 ETO22076.1 - 2 8.4 15.2 0.16 11.9 2.5 2.7 2 1 0 2 2 2 0 bZIP transcription factor Fib_alpha PF08702.5 ETO22076.1 - 2.1 8.4 12.4 3.6 7.6 8.6 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.4 ETO22076.1 - 4.1 7.6 14.5 6.4 6.9 1.7 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF904 PF06005.7 ETO22076.1 - 4.3 7.7 19.1 1.2 9.4 7.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DivIVA PF05103.8 ETO22076.1 - 5.1 7.1 15.7 11 6.0 10.9 1.6 1 0 0 1 1 1 0 DivIVA protein CCDC-167 PF15188.1 ETO22076.1 - 6.6 6.7 10.7 0.48 10.4 1.5 2.3 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 SSXT PF05030.7 ETO22077.1 - 0.005 16.3 2.7 0.023 14.2 1.9 2.2 1 0 0 1 1 1 1 SSXT protein (N-terminal region) Kelch_6 PF13964.1 ETO22078.1 - 1.1e-09 38.0 4.5 4.9e-05 23.3 0.1 4.2 3 1 1 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO22078.1 - 8.3e-07 28.6 0.3 0.03 14.0 0.0 3.6 2 2 1 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO22078.1 - 3.1e-06 26.7 1.1 0.016 14.9 0.0 4.2 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 ETO22078.1 - 3.5e-05 23.8 0.1 0.0005 20.1 0.0 2.9 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO22078.1 - 7.4e-05 22.2 3.4 0.013 15.0 0.0 4.1 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 ETO22078.1 - 0.023 14.6 9.3 0.62 10.0 0.1 5.2 5 1 0 5 5 5 0 Kelch motif WD40 PF00400.27 ETO22080.1 - 2.7e-57 188.6 27.8 1.4e-10 40.6 1.9 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO22080.1 - 2.6e-10 39.0 7.7 0.0014 16.8 0.1 5.0 1 1 4 5 5 5 4 Nucleoporin Nup120/160 WD40 PF00400.27 ETO22081.1 - 2.8e-187 600.8 40.7 3.6e-14 52.0 0.1 14.7 14 0 0 14 14 14 14 WD domain, G-beta repeat NACHT PF05729.7 ETO22081.1 - 4.2e-10 39.5 0.0 7.7e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Gmad1 PF10647.4 ETO22081.1 - 9.2e-06 25.2 11.9 0.053 12.9 0.4 5.5 1 1 4 6 6 6 4 Lipoprotein LpqB beta-propeller domain AAA_18 PF13238.1 ETO22081.1 - 1.9e-05 24.9 0.1 1.9e-05 24.9 0.1 3.7 3 1 0 3 3 3 1 AAA domain Pentapeptide_4 PF13599.1 ETO22081.1 - 0.00014 21.5 0.2 0.00038 20.2 0.2 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA_22 PF13401.1 ETO22081.1 - 0.00018 21.6 0.0 0.00049 20.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Pentapeptide_3 PF13576.1 ETO22081.1 - 0.00072 19.3 0.4 0.0019 18.0 0.3 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETO22081.1 - 0.0022 17.2 0.1 0.0044 16.2 0.0 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) AAA_17 PF13207.1 ETO22081.1 - 0.0041 17.9 0.0 0.029 15.1 0.0 2.5 1 0 0 1 1 1 1 AAA domain Germane PF10646.4 ETO22081.1 - 0.0059 16.7 0.3 17 5.6 0.0 5.0 4 1 0 4 4 4 0 Sporulation and spore germination AAA PF00004.24 ETO22081.1 - 0.028 14.6 0.1 0.1 12.8 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) PD40 PF07676.7 ETO22081.1 - 0.34 10.6 34.7 61 3.4 0.1 12.0 13 0 0 13 13 13 0 WD40-like Beta Propeller Repeat Pkinase PF00069.20 ETO22082.1 - 2.8e-10 39.7 0.1 1.1e-09 37.7 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain DUF3049 PF11250.3 ETO22082.1 - 0.094 12.4 0.0 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3049) RRM_6 PF14259.1 ETO22083.1 - 6.1e-06 26.1 0.1 1e-05 25.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO22083.1 - 0.002 17.7 0.3 0.0036 16.9 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_C93 PF06035.6 ETO22083.1 - 0.045 13.1 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial transglutaminase-like cysteine proteinase BTLCP Sed5p PF11416.3 ETO22083.1 - 0.073 12.5 0.4 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 Integral membrane protein Sed5p Mmp37 PF09139.6 ETO22084.1 - 1.7e-23 83.1 0.0 2.5e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 Mmp37 PF09139.6 ETO22085.1 - 6.1e-12 45.2 0.8 6.8e-12 45.0 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 Metallophos PF00149.23 ETO22086.1 - 9.8e-32 109.9 2.9 9.8e-32 109.9 2.0 3.7 3 1 0 3 3 3 1 Calcineurin-like phosphoesterase MadL PF03817.8 ETO22087.1 - 0.045 13.6 0.1 0.075 12.8 0.1 1.3 1 0 0 1 1 1 0 Malonate transporter MadL subunit TPR_12 PF13424.1 ETO22090.1 - 2.4e-86 283.6 35.1 8.3e-14 51.2 0.9 11.8 6 3 3 12 12 12 12 Tetratricopeptide repeat TPR_10 PF13374.1 ETO22090.1 - 8.4e-51 168.5 8.4 5.4e-05 22.9 0.0 15.4 17 0 0 17 17 17 10 Tetratricopeptide repeat TPR_11 PF13414.1 ETO22090.1 - 2.9e-42 142.1 40.5 2.4e-06 27.1 1.0 11.9 6 4 6 13 13 13 12 TPR repeat TPR_1 PF00515.23 ETO22090.1 - 5.5e-41 136.5 50.9 0.00015 21.1 0.0 17.2 17 1 0 17 17 17 12 Tetratricopeptide repeat TPR_2 PF07719.12 ETO22090.1 - 4.9e-38 125.9 49.7 0.0019 17.9 0.0 17.1 17 1 0 17 17 17 10 Tetratricopeptide repeat TPR_7 PF13176.1 ETO22090.1 - 3.7e-36 120.0 29.7 0.0016 18.1 0.1 16.3 16 1 0 16 16 16 7 Tetratricopeptide repeat TPR_14 PF13428.1 ETO22090.1 - 6.5e-22 76.0 0.6 0.42 11.3 0.0 14.2 14 2 2 16 16 15 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO22090.1 - 1.3e-19 68.4 32.7 0.14 12.0 0.0 15.3 15 0 0 15 15 15 5 Tetratricopeptide repeat TPR_6 PF13174.1 ETO22090.1 - 1.6e-11 43.8 14.2 1.4 9.5 0.0 11.2 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO22090.1 - 2.2e-09 37.7 0.9 0.32 11.7 0.0 7.7 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO22090.1 - 4.3e-06 26.5 16.6 5 7.5 0.0 9.9 12 0 0 12 12 10 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO22090.1 - 9.5e-05 21.5 0.1 0.62 9.3 0.0 5.8 5 0 0 5 5 5 1 SHNi-TPR DUF386 PF04074.7 ETO22090.1 - 0.00067 19.2 0.4 0.1 12.0 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF386) Apc3 PF12895.2 ETO22090.1 - 0.0062 16.6 41.5 0.16 12.1 0.1 9.3 7 2 3 10 10 10 3 Anaphase-promoting complex, cyclosome, subunit 3 SAND PF01342.16 ETO22090.1 - 0.0097 15.5 5.6 6.1 6.6 0.0 5.6 7 0 0 7 7 6 1 SAND domain HemS PF05171.7 ETO22090.1 - 0.048 13.4 0.0 0.15 11.8 0.0 1.9 1 0 0 1 1 1 0 Haemin-degrading HemS.ChuX domain PAP2 PF01569.16 ETO22091.1 - 1.5e-13 50.5 14.5 1.5e-12 47.2 10.1 2.4 1 1 0 1 1 1 1 PAP2 superfamily DUF4064 PF13273.1 ETO22091.1 - 0.019 15.0 0.9 0.019 15.0 0.6 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF4064) Cortexin PF11057.3 ETO22091.1 - 0.1 12.1 0.3 0.9 9.1 0.4 2.4 2 0 0 2 2 2 0 Cortexin of kidney CTP_transf_2 PF01467.21 ETO22093.1 - 6.1e-09 36.1 0.2 2e-07 31.1 0.0 2.4 2 0 0 2 2 2 1 Cytidylyltransferase DUF4216 PF13952.1 ETO22093.1 - 0.17 11.4 2.1 0.66 9.4 0.0 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4216) PSII_Pbs27 PF13326.1 ETO22094.1 - 0.056 13.4 0.9 0.94 9.4 0.0 2.3 2 0 0 2 2 2 0 Photosystem II Pbs27 Metallophos PF00149.23 ETO22095.1 - 6e-06 25.7 0.7 7.5e-06 25.4 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EphA2_TM PF14575.1 ETO22095.1 - 0.0089 16.3 0.2 0.015 15.7 0.1 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF2815 PF10991.3 ETO22095.1 - 0.18 11.3 1.7 0.29 10.6 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2815) DUF1776 PF08643.5 ETO22098.1 - 0.014 14.5 0.6 0.017 14.3 0.5 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) YopD PF05844.7 ETO22098.1 - 0.019 14.0 3.1 0.022 13.8 2.2 1.1 1 0 0 1 1 1 0 YopD protein Exonuc_VII_L PF02601.10 ETO22098.1 - 0.02 14.0 5.8 0.023 13.9 4.0 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Apolipoprotein PF01442.13 ETO22098.1 - 0.063 12.7 4.7 0.081 12.4 3.0 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DNA_primase_lrg PF04104.9 ETO22098.1 - 0.099 11.8 3.5 0.12 11.6 2.4 1.1 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit Vps39_2 PF10367.4 ETO22098.1 - 0.1 12.7 4.4 0.1 12.7 2.3 1.5 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 PglZ PF08665.7 ETO22098.1 - 0.15 11.7 2.0 0.17 11.5 1.4 1.0 1 0 0 1 1 1 0 PglZ domain DUF3260 PF11658.3 ETO22098.1 - 0.23 9.5 1.7 0.26 9.3 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) CK_II_beta PF01214.13 ETO22098.1 - 0.23 10.9 1.7 0.26 10.7 0.7 1.4 1 1 0 1 1 1 0 Casein kinase II regulatory subunit DUF972 PF06156.8 ETO22098.1 - 0.25 11.7 5.3 0.37 11.1 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Rad60-SLD_2 PF13881.1 ETO22098.1 - 0.25 11.2 2.6 0.29 11.0 1.8 1.1 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like GLE1 PF07817.8 ETO22098.1 - 0.26 10.1 6.2 0.29 10.0 4.3 1.1 1 0 0 1 1 1 0 GLE1-like protein DUF3574 PF12098.3 ETO22098.1 - 0.27 10.8 2.2 0.34 10.5 1.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3574) DUF3340 PF11818.3 ETO22098.1 - 0.31 11.0 6.5 0.051 13.5 1.0 2.1 1 1 1 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) DUF883 PF05957.8 ETO22098.1 - 0.43 11.0 2.6 0.49 10.8 0.4 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) SLIDE PF09111.5 ETO22098.1 - 0.9 9.2 6.2 1.2 8.8 4.3 1.4 1 1 0 1 1 1 0 SLIDE Ground-like PF04155.13 ETO22098.1 - 3.7 7.9 5.7 15 5.9 3.4 2.2 1 1 0 1 1 1 0 Ground-like domain HAND PF09110.6 ETO22098.1 - 5.3 7.4 9.5 21 5.5 6.6 1.8 1 1 0 1 1 1 0 HAND Macoilin PF09726.4 ETO22099.1 - 0.27 9.4 4.0 0.33 9.1 2.8 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF3763 PF12592.3 ETO22100.1 - 0.036 13.6 0.9 0.086 12.4 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3763) DUF605 PF04652.11 ETO22100.1 - 0.088 12.1 20.4 0.097 12.0 14.1 1.1 1 0 0 1 1 1 0 Vta1 like Neur_chan_memb PF02932.11 ETO22100.1 - 3.4 7.4 6.0 5.3 6.8 4.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region XRN_N PF03159.13 ETO22101.1 - 0.0047 16.3 0.2 0.0066 15.8 0.1 1.2 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus 60KD_IMP PF02096.15 ETO22101.1 - 0.11 12.1 0.2 0.16 11.6 0.2 1.2 1 0 0 1 1 1 0 60Kd inner membrane protein VIT1 PF01988.14 ETO22101.1 - 0.14 11.5 0.7 0.17 11.3 0.5 1.1 1 0 0 1 1 1 0 VIT family SP_C-Propep PF08999.5 ETO22101.1 - 0.78 9.2 5.0 1.2 8.6 3.5 1.3 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide EcKinase PF02958.15 ETO22103.1 - 0.003 16.7 0.8 0.0031 16.7 0.5 1.0 1 0 0 1 1 1 1 Ecdysteroid kinase Peptidase_S49_N PF08496.5 ETO22103.1 - 0.0049 16.6 1.3 0.0054 16.5 0.9 1.1 1 0 0 1 1 1 1 Peptidase family S49 N-terminal DUF2229 PF09989.4 ETO22103.1 - 0.14 11.5 1.4 0.15 11.5 1.0 1.0 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF3492 PF11997.3 ETO22103.1 - 0.16 11.4 0.6 0.15 11.5 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) DUF2317 PF10079.4 ETO22103.1 - 0.19 10.2 4.0 0.2 10.1 2.8 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Sds3 PF08598.6 ETO22103.1 - 0.4 10.1 6.9 0.47 9.9 4.8 1.1 1 0 0 1 1 1 0 Sds3-like RRF PF01765.14 ETO22103.1 - 1.5 8.2 10.7 0.47 9.8 3.3 1.9 1 1 1 2 2 2 0 Ribosome recycling factor DUF3899 PF13038.1 ETO22103.1 - 5.9 7.1 6.6 3.2 7.9 3.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3899) Syja_N PF02383.13 ETO22104.1 - 1.4e-74 250.7 0.1 1.4e-74 250.7 0.0 1.9 2 0 0 2 2 2 1 SacI homology domain RNA_polI_A34 PF08208.6 ETO22104.1 - 0.0022 17.6 14.7 0.0037 16.9 10.2 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 NARP1 PF12569.3 ETO22104.1 - 0.0068 15.2 8.3 0.0096 14.7 5.8 1.2 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 CDC45 PF02724.9 ETO22104.1 - 0.0086 14.1 12.7 0.013 13.5 8.8 1.2 1 0 0 1 1 1 1 CDC45-like protein Daxx PF03344.10 ETO22104.1 - 0.11 10.9 25.0 0.21 10.0 17.3 1.3 1 0 0 1 1 1 0 Daxx Family GAGA_bind PF06217.7 ETO22104.1 - 0.12 12.2 9.5 0.2 11.5 6.6 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Ycf1 PF05758.7 ETO22104.1 - 0.45 8.1 15.5 0.62 7.7 10.7 1.1 1 0 0 1 1 1 0 Ycf1 Cytomega_UL84 PF06284.6 ETO22104.1 - 0.62 8.4 2.7 1 7.6 1.9 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Zip PF02535.17 ETO22104.1 - 0.63 8.9 1.6 0.83 8.5 1.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.11 ETO22104.1 - 1.2 8.9 4.0 1.8 8.3 2.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DDHD PF02862.12 ETO22104.1 - 1.6 8.4 7.1 3.1 7.5 4.9 1.4 1 0 0 1 1 1 0 DDHD domain Nop14 PF04147.7 ETO22104.1 - 1.8 6.3 23.8 2.5 5.9 16.5 1.1 1 0 0 1 1 1 0 Nop14-like family FAM60A PF15396.1 ETO22104.1 - 2.5 7.7 9.9 28 4.3 7.4 1.9 2 0 0 2 2 2 0 Protein Family FAM60A Astro_capsid PF03115.9 ETO22104.1 - 3.8 5.6 7.0 4.8 5.2 4.8 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Pox_Ag35 PF03286.9 ETO22104.1 - 4.7 6.6 22.0 8.7 5.8 15.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Atrophin-1 PF03154.10 ETO22104.1 - 5.5 5.0 10.1 8 4.4 7.0 1.2 1 0 0 1 1 1 0 Atrophin-1 family Tom37_C PF11801.3 ETO22104.1 - 5.6 6.7 9.9 18 5.1 6.8 1.9 1 1 0 1 1 1 0 Tom37 C-terminal domain DUF2722 PF10846.3 ETO22104.1 - 6.5 5.6 13.4 11 4.9 9.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) NIF PF03031.13 ETO22105.1 - 3.4e-10 39.8 1.1 1.7e-09 37.5 0.7 2.1 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Imm-NTF2 PF15655.1 ETO22106.1 - 0.017 15.5 0.6 0.12 12.8 0.0 2.2 2 0 0 2 2 2 0 NTF2 fold immunity protein Rbsn PF11464.3 ETO22108.1 - 0.019 14.5 0.1 0.21 11.1 0.0 2.3 2 0 0 2 2 2 0 Rabenosyn Rab binding domain DUF2205 PF10224.4 ETO22109.1 - 0.024 14.2 2.0 0.024 14.2 1.4 3.9 4 1 1 5 5 5 0 Predicted coiled-coil protein (DUF2205) Adaptin_binding PF10199.4 ETO22109.1 - 2.8 8.2 11.0 0.29 11.4 2.2 2.2 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 UPF0449 PF15136.1 ETO22109.1 - 4.1 7.6 10.3 0.21 11.7 1.3 2.8 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 Ank PF00023.25 ETO22112.1 - 1.8e-05 24.3 0.1 0.29 11.0 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 ETO22112.1 - 4.5e-05 23.7 0.1 0.00061 20.0 0.0 2.5 1 1 2 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO22112.1 - 0.00019 21.5 0.0 1.4 9.3 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) LktC PF06261.6 ETO22112.1 - 0.013 15.2 0.2 0.017 14.8 0.1 1.3 1 0 0 1 1 1 0 Actinobacillus actinomycetemcomitans leukotoxin activator LktC Ank_4 PF13637.1 ETO22112.1 - 0.021 15.3 0.1 0.14 12.7 0.1 2.2 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO22112.1 - 0.038 14.2 0.1 16 6.0 0.0 2.9 2 1 0 2 2 2 0 Ankyrin repeat His_binding PF02098.11 ETO22112.1 - 0.05 13.4 0.3 0.094 12.5 0.1 1.5 1 1 0 1 1 1 0 Tick histamine binding protein Lentivirus_VIF PF05851.6 ETO22112.1 - 0.11 11.1 0.2 0.11 11.1 0.1 2.2 1 1 0 2 2 2 0 Lentivirus virion infectivity factor (VIF) WD40 PF00400.27 ETO22115.1 - 3.3e-35 118.7 3.5 1.2e-13 50.3 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 ETO22115.1 - 8.1e-11 41.9 0.6 0.00011 22.0 0.1 3.0 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO22115.1 - 4.4e-07 28.4 2.9 0.083 11.0 0.0 3.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO22115.1 - 6e-05 21.5 0.1 0.00029 19.2 0.0 2.0 1 1 0 2 2 2 1 Cytochrome D1 heme domain Str_synth PF03088.11 ETO22115.1 - 0.00064 19.7 0.1 1.8 8.6 0.0 3.5 3 1 0 3 3 3 2 Strictosidine synthase RicinB_lectin_2 PF14200.1 ETO22115.1 - 0.0034 17.7 0.0 0.012 15.9 0.0 1.9 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like TFIIIC_delta PF12657.2 ETO22115.1 - 0.045 13.4 1.3 0.21 11.2 0.9 2.2 1 1 0 1 1 1 0 Transcription factor IIIC subunit delta N-term Ku_N PF03731.10 ETO22116.1 - 5.6e-11 42.2 0.8 7.4e-11 41.9 0.6 1.1 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.11 ETO22116.1 - 1.1e-06 28.2 0.0 1.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Fringe PF02434.11 ETO22116.1 - 0.12 11.5 2.3 0.24 10.5 0.9 1.7 1 1 0 2 2 2 0 Fringe-like TPR_12 PF13424.1 ETO22117.1 - 8.5e-65 214.6 21.8 3.4e-22 78.1 0.7 5.3 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETO22117.1 - 2.2e-42 142.5 19.5 1.4e-15 56.7 0.4 5.4 4 1 1 5 5 5 4 TPR repeat TPR_10 PF13374.1 ETO22117.1 - 2.5e-41 138.4 0.0 9.3e-09 34.9 0.0 6.9 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETO22117.1 - 3.1e-38 127.8 42.4 2.1e-09 36.6 0.5 7.9 8 0 0 8 8 7 7 Tetratricopeptide repeat TPR_7 PF13176.1 ETO22117.1 - 1.9e-34 114.7 8.9 1.2e-08 34.1 0.0 8.6 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETO22117.1 - 3.3e-30 101.5 35.9 1.5e-06 27.6 0.2 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETO22117.1 - 2.5e-29 98.8 47.4 1.4e-09 37.0 0.6 8.8 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 ETO22117.1 - 2.1e-17 63.2 1.5 0.00014 22.4 0.0 5.6 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 ETO22117.1 - 3.2e-16 58.1 6.0 0.0069 16.4 0.0 7.1 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO22117.1 - 1.2e-13 50.3 0.1 0.49 11.1 0.0 7.0 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO22117.1 - 3.5e-10 39.6 20.1 0.3 11.6 0.0 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 ETO22117.1 - 5.1e-08 32.9 15.9 0.00046 20.2 2.2 4.3 2 2 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 ETO22117.1 - 2e-07 30.6 39.9 0.034 13.9 0.4 7.3 8 0 0 8 8 8 5 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO22117.1 - 2.4e-07 29.9 5.4 3.8 6.8 0.0 6.0 6 0 0 6 6 6 3 SHNi-TPR TPR_19 PF14559.1 ETO22117.1 - 6.7e-07 29.5 4.3 0.013 15.8 0.1 4.7 5 1 1 6 6 4 3 Tetratricopeptide repeat MIT PF04212.13 ETO22117.1 - 0.00069 19.4 17.2 3.7 7.5 0.0 7.2 8 0 0 8 8 8 1 MIT (microtubule interacting and transport) domain NIF3 PF01784.13 ETO22117.1 - 0.00089 18.9 0.2 0.81 9.2 0.0 2.5 2 0 0 2 2 2 2 NIF3 (NGG1p interacting factor 3) PPR PF01535.15 ETO22117.1 - 0.0016 18.2 6.9 0.029 14.3 0.1 5.0 7 0 0 7 7 5 1 PPR repeat Sel1 PF08238.7 ETO22117.1 - 0.67 10.6 24.2 4 8.2 0.1 6.1 6 0 0 6 6 6 0 Sel1 repeat PPR_2 PF13041.1 ETO22117.1 - 2.9 7.9 8.4 6.5 6.8 0.0 4.8 6 0 0 6 6 5 0 PPR repeat family Nucleoplasmin PF03066.10 ETO22118.1 - 0.21 11.1 3.4 0.53 9.7 2.3 1.6 1 0 0 1 1 1 0 Nucleoplasmin DUF3488 PF11992.3 ETO22121.1 - 0.13 10.8 8.4 0.016 13.8 2.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) AzlD PF05437.7 ETO22121.1 - 8.3 6.4 10.3 0.61 10.0 2.2 2.5 3 0 0 3 3 3 0 Branched-chain amino acid transport protein (AzlD) DUF2890 PF11081.3 ETO22123.1 - 0.00068 19.7 6.3 0.00094 19.2 4.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2890) Pox_RNA_Pol_19 PF05320.7 ETO22123.1 - 0.001 18.8 6.5 0.0014 18.3 4.5 1.1 1 0 0 1 1 1 1 Poxvirus DNA-directed RNA polymerase 19 kDa subunit RRN3 PF05327.6 ETO22123.1 - 0.0099 14.0 2.8 0.013 13.6 1.9 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 YL1 PF05764.8 ETO22123.1 - 0.015 14.9 13.5 0.021 14.4 9.4 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.7 ETO22123.1 - 0.02 12.8 13.2 0.025 12.5 9.2 1.1 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.6 ETO22123.1 - 0.029 12.2 6.9 0.034 12.0 4.8 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4628 PF15429.1 ETO22123.1 - 0.037 13.4 4.6 0.05 13.0 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) Sigma70_ner PF04546.8 ETO22123.1 - 0.044 13.3 11.0 0.057 13.0 7.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Med8 PF10232.4 ETO22123.1 - 0.045 13.2 0.2 0.045 13.2 0.2 2.1 1 1 1 2 2 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Daxx PF03344.10 ETO22123.1 - 0.062 11.7 11.9 0.079 11.4 8.3 1.2 1 0 0 1 1 1 0 Daxx Family Tim54 PF11711.3 ETO22123.1 - 0.16 10.5 3.8 0.2 10.2 2.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Radial_spoke PF04712.7 ETO22123.1 - 0.25 10.0 9.9 0.3 9.7 6.8 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein CENP-B_dimeris PF09026.5 ETO22123.1 - 0.25 11.6 15.0 0.16 12.2 9.2 1.6 2 0 0 2 2 1 0 Centromere protein B dimerisation domain CDC45 PF02724.9 ETO22123.1 - 0.93 7.4 8.1 1.2 7.0 5.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Prp19_bind PF06991.6 ETO22123.1 - 1.3 8.2 13.9 1.7 7.8 9.6 1.1 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain DNA_pol_phi PF04931.8 ETO22123.1 - 1.4 6.6 14.8 1.7 6.3 10.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi TFIIF_alpha PF05793.7 ETO22123.1 - 1.5 7.1 16.0 2.1 6.6 11.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nucleoplasmin PF03066.10 ETO22123.1 - 1.6 8.2 19.8 3.4 7.1 13.5 1.6 2 0 0 2 2 2 0 Nucleoplasmin TRAP_alpha PF03896.11 ETO22123.1 - 1.7 7.5 9.5 2.4 7.1 6.6 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF506 PF04720.7 ETO22123.1 - 2 8.0 5.1 2.7 7.5 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF506) NOA36 PF06524.7 ETO22123.1 - 2.3 7.3 8.9 3.5 6.7 6.1 1.2 1 0 0 1 1 1 0 NOA36 protein HSP90 PF00183.13 ETO22123.1 - 2.9 6.1 13.4 4 5.7 9.3 1.2 1 0 0 1 1 1 0 Hsp90 protein CobT PF06213.7 ETO22123.1 - 3.6 6.6 13.7 4.7 6.2 9.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SGT1 PF07093.6 ETO22123.1 - 8.4 4.6 13.7 11 4.3 9.5 1.1 1 0 0 1 1 1 0 SGT1 protein IFT57 PF10498.4 ETO22123.1 - 9.7 4.8 11.6 13 4.3 8.1 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Hydrolase PF00702.21 ETO22126.1 - 4.5e-06 27.2 0.2 5.9e-06 26.8 0.1 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETO22126.1 - 3.6e-05 23.9 0.0 4.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 ETO22126.1 - 0.0037 16.8 0.3 0.0088 15.6 0.1 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Anti-adapt_IraP PF10796.4 ETO22126.1 - 0.13 12.6 1.2 0.47 10.8 0.1 2.1 1 1 1 2 2 2 0 Sigma-S stabilisation anti-adaptor protein NTPase_I-T PF01931.13 ETO22128.1 - 3.4e-12 46.4 0.0 4.4e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF84 Hydrolase_like2 PF13246.1 ETO22129.1 - 2.3e-11 43.4 0.1 6.2e-11 42.0 0.1 1.8 1 1 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 ETO22129.1 - 9.1e-09 35.7 0.1 2.4e-08 34.3 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 ETO22129.1 - 3e-08 34.3 0.0 9.6e-07 29.4 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3016 PF11454.3 ETO22129.1 - 0.023 14.3 0.0 0.051 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) Tox-HNH-HHH PF15637.1 ETO22131.1 - 0.016 14.9 0.1 0.025 14.3 0.1 1.3 1 0 0 1 1 1 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif Secretin PF00263.16 ETO22131.1 - 0.041 13.2 0.1 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial type II and III secretion system protein Consortin_C PF15281.1 ETO22132.1 - 0.024 14.1 0.0 0.087 12.3 0.0 2.0 1 0 0 1 1 1 0 Consortin C-terminus IncA PF04156.9 ETO22132.1 - 0.044 13.3 0.3 0.044 13.3 0.2 1.6 2 0 0 2 2 2 0 IncA protein CcmH PF03918.9 ETO22132.1 - 0.2 10.6 2.3 0.81 8.6 0.1 2.8 2 1 1 3 3 3 0 Cytochrome C biogenesis protein PrgI PF12666.2 ETO22132.1 - 4.4 7.5 13.3 3.7 7.7 0.1 3.9 4 0 0 4 4 4 0 PrgI family protein Protocadherin PF08374.6 ETO22132.1 - 7.1 6.1 9.0 17 4.9 2.8 2.3 2 0 0 2 2 2 0 Protocadherin BpuJI_N PF11564.3 ETO22134.1 - 0.044 12.7 0.7 0.063 12.2 0.5 1.2 1 0 0 1 1 1 0 Restriction endonuclease BpuJI - N terminal FLYWCH PF04500.11 ETO22136.1 - 0.48 10.3 6.6 0.87 9.5 3.3 2.6 2 1 0 2 2 2 0 FLYWCH zinc finger domain Lectin_N PF03954.9 ETO22137.1 - 9.8 5.5 7.2 2.4 7.5 2.4 1.9 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Kinesin PF00225.18 ETO22139.1 - 2.9e-08 32.8 0.6 2.7e-07 29.6 0.1 2.3 2 0 0 2 2 2 1 Kinesin motor domain FliJ PF02050.11 ETO22139.1 - 0.00019 21.4 2.2 0.00019 21.4 1.6 2.1 2 0 0 2 2 2 1 Flagellar FliJ protein SlyX PF04102.7 ETO22139.1 - 0.0016 18.7 2.5 0.007 16.7 1.7 2.2 1 0 0 1 1 1 1 SlyX FolB PF02152.13 ETO22139.1 - 0.034 14.2 1.7 0.21 11.7 0.1 2.5 2 0 0 2 2 2 0 Dihydroneopterin aldolase EMP24_GP25L PF01105.19 ETO22139.1 - 0.043 13.5 0.8 0.14 11.8 0.5 1.9 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD NEMO PF11577.3 ETO22139.1 - 0.19 11.5 9.2 1.2 8.9 2.6 2.6 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO HSP20 PF00011.16 ETO22139.1 - 0.25 11.1 0.1 0.25 11.1 0.1 2.9 3 0 0 3 3 3 0 Hsp20/alpha crystallin family DUF3213 PF11491.3 ETO22139.1 - 0.33 10.8 4.4 0.58 10.0 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3213) DUF2508 PF10704.4 ETO22139.1 - 0.6 10.3 6.7 0.29 11.3 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) DUF745 PF05335.8 ETO22139.1 - 0.8 9.2 9.8 0.018 14.5 1.4 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF745) Atg14 PF10186.4 ETO22139.1 - 1.6 7.6 7.3 0.049 12.5 0.7 1.8 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF87 PF01935.12 ETO22139.1 - 1.9 8.2 8.0 0.43 10.3 1.9 2.4 1 1 2 3 3 3 0 Domain of unknown function DUF87 Kinetocho_Slk19 PF12709.2 ETO22139.1 - 2.6 8.2 9.7 0.52 10.4 3.6 2.2 2 0 0 2 2 2 0 Central kinetochore-associated Syntaxin_2 PF14523.1 ETO22139.1 - 2.6 8.1 7.8 1.2 9.1 2.4 2.5 2 1 0 2 2 2 0 Syntaxin-like protein IncA PF04156.9 ETO22139.1 - 6.8 6.2 9.3 0.46 10.0 1.9 2.2 2 0 0 2 2 2 0 IncA protein WD40 PF00400.27 ETO22140.1 - 3.1e-22 77.5 15.4 2.9e-06 26.9 0.1 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat Ribosomal_S14 PF00253.16 ETO22140.1 - 0.044 13.1 0.0 0.18 11.2 0.0 2.0 1 1 0 1 1 1 0 Ribosomal protein S14p/S29e SIT PF15330.1 ETO22142.1 - 0.036 14.1 0.1 0.036 14.1 0.1 2.6 2 1 1 3 3 3 0 SHP2-interacting transmembrane adaptor protein, SIT TMCO5 PF14992.1 ETO22142.1 - 0.22 10.6 0.1 0.37 9.8 0.1 1.3 1 0 0 1 1 1 0 TMCO5 family EphA2_TM PF14575.1 ETO22142.1 - 2 8.8 0.0 2 8.8 0.0 3.4 2 2 2 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain OppC_N PF12911.2 ETO22142.1 - 3.4 7.1 13.8 4.8 6.6 0.5 4.1 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C Nop14 PF04147.7 ETO22145.1 - 0.0083 14.1 24.0 0.012 13.5 16.7 1.3 1 0 0 1 1 1 1 Nop14-like family EST1_DNA_bind PF10373.4 ETO22147.1 - 0.015 14.5 0.9 0.018 14.2 0.1 1.6 1 1 1 2 2 2 0 Est1 DNA/RNA binding domain Voltage_CLC PF00654.15 ETO22149.1 - 1.5e-25 90.0 2.2 1.7e-25 89.8 1.5 1.0 1 0 0 1 1 1 1 Voltage gated chloride channel TauE PF01925.14 ETO22149.1 - 0.0021 17.5 1.4 0.62 9.4 0.0 2.3 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE 5TM-5TMR_LYT PF07694.7 ETO22149.1 - 0.22 10.8 5.2 0.38 10.0 1.5 2.2 2 0 0 2 2 2 0 5TMR of 5TMR-LYT PDZ PF00595.19 ETO22150.1 - 5.6e-07 29.6 0.0 7.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 ETO22150.1 - 0.00078 19.2 0.0 0.0023 17.8 0.0 1.7 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.1 ETO22150.1 - 0.11 12.3 0.0 0.29 10.9 0.0 1.7 2 0 0 2 2 2 0 Tricorn protease PDZ domain PH PF00169.24 ETO22151.1 - 4e-09 36.6 0.1 1.3e-08 34.9 0.0 1.8 1 1 1 2 2 2 1 PH domain PH_11 PF15413.1 ETO22151.1 - 0.0022 18.1 0.0 0.0042 17.3 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Lipase_GDSL_3 PF14606.1 ETO22151.1 - 0.018 14.7 0.1 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Toxin-deaminase PF14424.1 ETO22151.1 - 0.094 12.6 0.1 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases DUF3292 PF11696.3 ETO22152.1 - 0.37 8.6 3.0 0.37 8.5 1.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3292) Menin PF05053.8 ETO22153.1 - 0.05 11.7 2.8 0.055 11.6 1.9 1.1 1 0 0 1 1 1 0 Menin PEARLI-4 PF05278.7 ETO22153.1 - 0.083 12.2 1.0 0.11 11.8 0.7 1.3 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Pex14_N PF04695.8 ETO22153.1 - 0.15 12.0 4.7 0.2 11.6 3.3 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2457 PF10446.4 ETO22153.1 - 0.16 10.6 4.7 0.19 10.4 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FlaG PF03646.10 ETO22153.1 - 1.2 9.3 8.0 1.9 8.6 5.5 1.3 1 0 0 1 1 1 0 FlaG protein RP-C_C PF11800.3 ETO22153.1 - 1.2 8.7 4.4 1.5 8.4 3.0 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF912 PF06024.7 ETO22153.1 - 1.5 8.8 7.2 2.6 8.1 5.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Secretin_N_2 PF07655.8 ETO22153.1 - 1.6 9.1 11.9 2.3 8.6 8.2 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain PT PF04886.7 ETO22154.1 - 1.5e-27 94.5 152.7 2.3e-09 36.3 15.1 10.8 4 3 6 10 10 10 8 PT repeat PDGLE PF13190.1 ETO22154.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 PDGLE domain DUF3309 PF11752.3 ETO22154.1 - 0.24 11.2 2.8 0.42 10.4 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3309) DUF373 PF04123.8 ETO22155.1 - 0.63 8.9 5.7 0.66 8.9 3.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Macoilin PF09726.4 ETO22155.1 - 1.1 7.4 4.2 1.7 6.8 2.9 1.4 1 0 0 1 1 1 0 Transmembrane protein zf-CCHC_3 PF13917.1 ETO22156.1 - 0.014 15.1 0.8 0.032 13.9 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle Myosin_tail_1 PF01576.14 ETO22156.1 - 0.023 12.4 11.3 0.031 12.0 7.9 1.1 1 0 0 1 1 1 0 Myosin tail IncA PF04156.9 ETO22156.1 - 0.047 13.2 6.7 0.073 12.6 4.7 1.2 1 0 0 1 1 1 0 IncA protein TMF_TATA_bd PF12325.3 ETO22156.1 - 0.11 12.2 9.4 0.24 11.1 3.7 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding bZIP_1 PF00170.16 ETO22156.1 - 6.6 6.7 14.5 0.081 12.8 3.2 2.7 3 0 0 3 3 3 0 bZIP transcription factor DivIC PF04977.10 ETO22156.1 - 9 5.8 7.0 24 4.4 0.1 2.5 1 1 1 2 2 2 0 Septum formation initiator Pkinase PF00069.20 ETO22157.1 - 2.7e-19 69.3 0.0 3.6e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO22157.1 - 0.0046 16.0 0.0 0.0055 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETO22157.1 - 0.014 15.1 1.2 0.032 13.9 0.1 2.1 3 0 0 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.1 ETO22157.1 - 0.019 13.9 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.6 ETO22157.1 - 0.089 11.5 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF3677 PF12432.3 ETO22159.1 - 0.11 12.9 0.9 1.5 9.2 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3677) WD40 PF00400.27 ETO22160.1 - 3.4e-19 67.9 3.9 6.4e-08 32.1 0.0 4.2 3 1 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO22160.1 - 0.005 15.0 0.1 0.042 11.9 0.0 1.9 1 1 0 1 1 1 1 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO22160.1 - 0.081 12.7 0.6 0.58 9.9 0.3 2.2 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Kelch_1 PF01344.20 ETO22161.1 - 4.9e-07 29.1 3.7 0.021 14.3 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETO22161.1 - 2.5e-05 23.9 2.0 0.042 13.6 0.0 2.8 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO22161.1 - 5.1e-05 23.1 0.2 0.52 10.3 0.0 4.0 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 ETO22161.1 - 0.0032 17.1 4.0 1.9 8.3 0.6 3.4 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO22161.1 - 0.02 15.0 7.3 1.8 8.8 0.1 3.9 3 1 1 4 4 4 0 Kelch motif 5_nucleotid PF05761.9 ETO22162.1 - 1.9e-53 181.5 0.2 2.5e-53 181.2 0.1 1.0 1 0 0 1 1 1 1 5' nucleotidase family HAD_2 PF13419.1 ETO22162.1 - 0.0097 16.1 0.0 2.4 8.3 0.0 2.4 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase C2 PF00168.25 ETO22163.1 - 0.036 13.8 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 C2 domain Inhibitor_I71 PF12628.2 ETO22163.1 - 0.14 11.8 0.9 0.17 11.5 0.6 1.1 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor Rtf2 PF04641.7 ETO22163.1 - 0.25 10.5 5.9 0.24 10.5 4.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger CDC45 PF02724.9 ETO22163.1 - 0.25 9.3 4.6 0.21 9.5 3.2 1.1 1 0 0 1 1 1 0 CDC45-like protein HSP90 PF00183.13 ETO22163.1 - 0.29 9.5 9.1 0.26 9.6 6.3 1.1 1 0 0 1 1 1 0 Hsp90 protein FAM176 PF14851.1 ETO22163.1 - 1.6 8.3 4.4 1.8 8.2 3.0 1.2 1 0 0 1 1 1 0 FAM176 family DUF1510 PF07423.6 ETO22163.1 - 2.8 7.2 11.7 3.5 6.9 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pacs-1 PF10254.4 ETO22165.1 - 0.011 14.3 0.0 0.02 13.5 0.0 1.4 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein THAP PF05485.7 ETO22165.1 - 0.05 13.7 0.1 0.14 12.3 0.1 1.8 1 0 0 1 1 1 0 THAP domain Shisa PF13908.1 ETO22165.1 - 0.11 12.6 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator PI3K_1B_p101 PF10486.4 ETO22165.1 - 0.12 9.9 0.2 0.51 7.8 0.0 1.9 1 1 1 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit zf-LITAF-like PF10601.4 ETO22165.1 - 0.14 11.9 4.8 0.34 10.7 3.3 1.6 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain Tenui_PVC2 PF06656.6 ETO22165.1 - 0.76 7.4 4.9 1.1 6.9 3.4 1.2 1 0 0 1 1 1 0 Tenuivirus PVC2 protein RELT PF12606.3 ETO22165.1 - 1.3 8.1 7.5 3.1 7.0 5.2 1.5 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 WD40 PF00400.27 ETO22166.1 - 1.1e-16 59.9 9.7 3.7e-11 42.4 2.8 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat zf-TRAF PF02176.13 ETO22166.1 - 1.7e-05 25.1 5.9 1.7e-05 25.1 4.1 2.6 4 0 0 4 4 4 1 TRAF-type zinc finger Nup160 PF11715.3 ETO22166.1 - 7.1e-05 21.1 1.3 0.0001 20.6 0.4 1.4 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Vfa1 PF08432.5 ETO22166.1 - 0.0041 17.1 7.3 0.008 16.2 5.1 1.4 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 GCD14 PF08704.5 ETO22166.1 - 0.13 11.7 5.6 0.22 11.0 3.9 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit TMEM237 PF15383.1 ETO22166.1 - 0.48 9.5 4.9 0.79 8.8 3.4 1.4 1 0 0 1 1 1 0 Transmembrane protein 237 60KD_IMP PF02096.15 ETO22166.1 - 9.3 5.8 8.9 18 4.8 6.2 1.5 1 0 0 1 1 1 0 60Kd inner membrane protein UCH PF00443.24 ETO22167.1 - 2.3e-31 108.9 2.3 3e-31 108.5 1.6 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO22167.1 - 5.3e-13 49.0 1.3 7.6e-13 48.5 0.9 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TPR_11 PF13414.1 ETO22168.1 - 3.7e-09 36.1 9.7 1.8e-07 30.7 3.0 1.8 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 ETO22168.1 - 1.2e-06 27.9 6.5 0.0016 18.1 2.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO22168.1 - 1.5e-05 25.2 7.1 2.6e-05 24.4 4.9 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO22168.1 - 3.2e-05 23.3 7.1 0.04 13.5 2.4 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO22168.1 - 0.00029 20.6 5.3 0.0011 18.8 3.4 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TENA_THI-4 PF03070.11 ETO22168.1 - 0.00086 19.1 0.2 0.001 18.9 0.2 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Coatomer_E PF04733.9 ETO22168.1 - 0.0032 16.7 0.5 0.0032 16.7 0.3 1.6 2 0 0 2 2 2 1 Coatomer epsilon subunit TPR_16 PF13432.1 ETO22168.1 - 0.0067 17.0 4.3 0.011 16.4 3.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO22168.1 - 0.007 16.4 7.7 0.022 14.8 5.0 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 ETO22168.1 - 0.013 15.2 5.9 0.38 10.6 2.5 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETO22168.1 - 0.023 14.4 2.8 2.4 8.1 0.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETO22168.1 - 0.05 14.2 2.8 0.27 11.9 0.4 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 ETO22168.1 - 0.057 13.2 1.1 0.11 12.4 0.8 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat MIT PF04212.13 ETO22168.1 - 0.38 10.6 5.9 2.3 8.1 0.7 3.2 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 ETO22168.1 - 0.4 10.5 6.8 2.2 8.1 1.6 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 ETO22168.1 - 0.65 10.3 3.6 4.1 7.8 0.9 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO22168.1 - 1.1 9.8 6.5 17 6.1 0.4 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat Prefoldin PF02996.12 ETO22168.1 - 3.6 7.2 11.1 0.28 10.8 0.7 2.7 3 0 0 3 3 3 0 Prefoldin subunit Sec15 PF04091.7 ETO22169.1 - 1.3e-31 110.0 3.4 5.1e-12 45.7 0.0 3.6 2 1 0 3 3 3 3 Exocyst complex subunit Sec15-like SRP14 PF02290.10 ETO22170.1 - 0.54 10.2 4.6 0.41 10.6 0.8 2.3 2 0 0 2 2 2 0 Signal recognition particle 14kD protein Vps8 PF12816.2 ETO22171.1 - 3.5e-27 94.9 2.9 7.6e-27 93.8 2.0 1.5 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 DUF2435 PF10363.4 ETO22172.1 - 0.057 13.3 3.1 0.8 9.6 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2435) DUF1319 PF07028.6 ETO22172.1 - 0.54 10.4 8.6 0.4 10.8 2.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) EVI2A PF05399.6 ETO22172.1 - 3.6 6.7 5.5 9.9 5.3 2.3 2.1 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) Clathrin PF00637.15 ETO22173.1 - 1.8e-06 27.6 2.3 3.3e-06 26.7 1.2 1.6 2 0 0 2 2 2 1 Region in Clathrin and VPS Nab1 PF04902.7 ETO22173.1 - 0.063 12.7 0.3 0.098 12.1 0.2 1.2 1 0 0 1 1 1 0 Conserved region in Nab1 DUF2408 PF10303.4 ETO22174.1 - 0.066 13.3 0.6 0.16 12.0 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Barstar PF01337.13 ETO22174.1 - 0.076 12.8 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Barstar (barnase inhibitor) RuBisCO_large PF00016.15 ETO22174.1 - 0.078 11.8 0.0 0.27 10.0 0.0 1.7 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase large chain, catalytic domain zf-rbx1 PF12678.2 ETO22174.1 - 0.6 10.2 9.3 0.05 13.7 1.3 2.6 2 1 1 3 3 3 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 ETO22174.1 - 0.82 9.3 6.7 1 9.0 2.2 2.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO22174.1 - 3.9 7.3 6.9 9.6 6.1 2.6 3.0 2 1 0 2 2 2 0 Ring finger domain NST1 PF13945.1 ETO22175.1 - 0.29 11.1 22.7 0.083 12.9 5.0 2.4 2 0 0 2 2 2 0 Salt tolerance down-regulator Rtf2 PF04641.7 ETO22175.1 - 3.2 6.8 21.0 1.7 7.7 5.2 2.2 2 0 0 2 2 2 0 Rtf2 RING-finger EcoEI_R_C PF08463.5 ETO22176.1 - 0.038 13.8 0.2 0.056 13.3 0.1 1.3 1 0 0 1 1 1 0 EcoEI R protein C-terminal DUF3306 PF11748.3 ETO22176.1 - 0.049 14.2 0.2 0.078 13.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) MFS_2 PF13347.1 ETO22177.1 - 0.014 13.8 5.2 0.28 9.5 0.2 2.3 2 0 0 2 2 2 0 MFS/sugar transport protein Mem_trans PF03547.13 ETO22177.1 - 0.016 13.4 0.7 0.037 12.3 0.5 1.5 1 0 0 1 1 1 0 Membrane transport protein PUCC PF03209.10 ETO22177.1 - 0.023 13.4 0.3 0.023 13.4 0.2 2.4 2 1 1 3 3 3 0 PUCC protein DUF3487 PF11990.3 ETO22177.1 - 0.83 9.0 2.8 0.48 9.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) NfeD PF01957.13 ETO22177.1 - 1.1 9.3 4.8 0.86 9.7 0.3 2.6 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding AA_permease_2 PF13520.1 ETO22177.1 - 3.3 6.1 14.8 0.28 9.6 6.1 1.8 1 1 1 2 2 2 0 Amino acid permease Kelch_1 PF01344.20 ETO22179.1 - 1.1e-09 37.6 6.8 0.00011 21.6 0.2 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO22179.1 - 1.8e-09 37.3 6.9 0.00024 21.1 0.1 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO22179.1 - 3.5e-09 36.2 0.4 0.001 18.7 0.0 4.2 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO22179.1 - 4.2e-07 29.4 3.2 0.032 14.0 0.0 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO22179.1 - 0.025 14.7 0.1 2.2 8.5 0.0 3.0 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO22179.1 - 0.16 11.9 3.0 0.88 9.6 0.2 2.8 2 0 0 2 2 2 0 Kelch motif Pkinase PF00069.20 ETO22180.1 - 9.4e-13 47.9 0.0 1.1e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO22180.1 - 8.1e-05 21.8 0.0 0.00011 21.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase TACC PF05010.9 ETO22182.1 - 0.0019 18.0 27.7 0.0019 18.0 19.2 3.1 1 1 2 3 3 3 1 Transforming acidic coiled-coil-containing protein (TACC) ORF11CD3 PF10549.4 ETO22182.1 - 0.009 15.7 4.7 0.33 10.7 0.0 4.0 3 0 0 3 3 3 1 ORF11CD3 domain DUF1133 PF06576.6 ETO22182.1 - 0.64 9.1 7.5 0.31 10.1 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1133) DUF2937 PF11157.3 ETO22182.1 - 1.5 8.1 12.4 0.1 11.9 3.7 2.6 2 2 2 4 4 4 0 Protein of unknown function (DUF2937) Anoctamin PF04547.7 ETO22183.1 - 1.2e-65 221.9 11.3 1.4e-65 221.7 7.8 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel CRT-like PF08627.5 ETO22183.1 - 0.67 9.8 4.1 0.6 10.0 0.2 2.5 1 1 2 3 3 3 0 CRT-like Chorion_3 PF05387.6 ETO22184.1 - 1.7 7.9 4.4 3.2 7.1 3.1 1.4 1 0 0 1 1 1 0 Chorion family 3 P34-Arc PF04045.9 ETO22185.1 - 6.3e-22 78.0 0.2 8.6e-22 77.5 0.1 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc P34-Arc PF04045.9 ETO22186.1 - 3.8e-15 55.8 0.0 6.8e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc FH2 PF02181.18 ETO22187.1 - 1.7e-07 30.4 2.7 1.7e-07 30.4 1.9 2.3 1 1 0 2 2 2 1 Formin Homology 2 Domain Unstab_antitox PF09720.5 ETO22187.1 - 0.0049 16.5 1.9 0.011 15.4 0.4 2.2 2 0 0 2 2 2 1 Putative addiction module component DUF883 PF05957.8 ETO22187.1 - 0.022 15.1 1.4 0.022 15.1 1.0 2.8 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) DivIC PF04977.10 ETO22187.1 - 0.092 12.2 0.2 0.092 12.2 0.2 3.4 3 0 0 3 3 3 0 Septum formation initiator DUF4510 PF14971.1 ETO22187.1 - 0.3 11.2 4.8 0.064 13.4 0.7 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4510) Peptidase_C6 PF00851.13 ETO22187.1 - 0.38 9.3 9.5 0.47 9.0 6.3 1.3 1 1 0 1 1 1 0 Helper component proteinase DUF802 PF05650.6 ETO22187.1 - 1.4 9.1 4.1 6.4 6.9 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF802) PID_2 PF14719.1 ETO22187.1 - 3.3 7.3 8.4 0.43 10.1 0.9 2.2 1 1 1 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) SOBP PF15279.1 ETO22187.1 - 6.6 7.0 8.7 11 6.3 6.0 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein ALMT PF11744.3 ETO22189.1 - 0.065 11.8 3.4 0.094 11.3 2.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter KOG2701 PF09762.4 ETO22190.1 - 0.26 11.3 7.3 0.39 10.7 5.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein (DUF2037) Hydrolase_3 PF08282.7 ETO22191.1 - 0.49 9.9 2.6 0.52 9.8 0.1 1.9 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Ycf1 PF05758.7 ETO22192.1 - 3.2e-05 21.9 0.8 3.6e-05 21.7 0.5 1.2 1 0 0 1 1 1 1 Ycf1 FAM176 PF14851.1 ETO22192.1 - 0.0019 17.9 2.6 0.0083 15.8 1.8 2.2 1 1 0 1 1 1 1 FAM176 family OAD_gamma PF04277.8 ETO22192.1 - 0.051 13.9 0.5 0.051 13.9 0.4 2.8 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Tmemb_9 PF05434.6 ETO22192.1 - 6.6 6.4 9.1 0.062 13.0 0.8 1.7 2 0 0 2 2 2 0 TMEM9 DUF4381 PF14316.1 ETO22193.1 - 0.0091 16.1 0.2 0.015 15.4 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) WBP-1 PF11669.3 ETO22193.1 - 0.013 15.5 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 WW domain-binding protein 1 DUF2370 PF10176.4 ETO22193.1 - 0.032 13.5 0.1 0.043 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF1191 PF06697.7 ETO22193.1 - 0.055 12.2 0.0 0.084 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) MscS_TM PF12794.2 ETO22193.1 - 0.058 12.0 0.0 0.09 11.3 0.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 CCSMST1 PF15013.1 ETO22193.1 - 0.083 12.8 0.4 0.24 11.3 0.1 1.9 2 0 0 2 2 2 0 CCSMST1 family FixQ PF05545.6 ETO22193.1 - 0.68 9.6 2.6 1.7 8.3 1.8 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ RCR PF12273.3 ETO22193.1 - 1.3 9.6 3.5 2.4 8.6 2.4 1.4 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF3415 PF11895.3 ETO22194.1 - 0.0028 17.4 0.6 0.0052 16.6 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3415) EMP24_GP25L PF01105.19 ETO22195.1 - 5e-26 91.5 0.0 6e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2012 PF09430.5 ETO22195.1 - 0.13 12.0 0.1 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) DND1_DSRM PF14709.1 ETO22196.1 - 0.017 15.3 0.3 0.21 11.8 0.0 2.5 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.20 ETO22196.1 - 0.084 13.4 0.1 0.18 12.4 0.1 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif Pox_Ag35 PF03286.9 ETO22197.1 - 0.037 13.5 17.7 0.053 13.0 12.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.7 ETO22197.1 - 0.043 11.7 16.5 0.049 11.5 11.4 1.0 1 0 0 1 1 1 0 Nop14-like family LMBR1 PF04791.11 ETO22197.1 - 0.081 11.4 1.4 0.09 11.3 1.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DHHW PF14286.1 ETO22197.1 - 0.17 11.1 11.3 0.21 10.8 7.9 1.0 1 0 0 1 1 1 0 DHHW protein DUF2457 PF10446.4 ETO22197.1 - 0.28 9.8 21.1 0.32 9.6 14.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) GET2 PF08690.5 ETO22197.1 - 0.53 9.4 5.7 0.68 9.1 4.0 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 CDC45 PF02724.9 ETO22197.1 - 0.59 8.1 13.8 0.69 7.8 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.5 ETO22197.1 - 1 9.3 15.3 1.4 8.9 10.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TRAP_alpha PF03896.11 ETO22197.1 - 1.1 8.2 10.9 1.3 7.9 7.6 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF1510 PF07423.6 ETO22197.1 - 1.9 7.7 23.1 2.7 7.2 16.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RRN3 PF05327.6 ETO22197.1 - 4.7 5.2 15.6 6.2 4.8 10.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RXT2_N PF08595.6 ETO22197.1 - 6.7 6.5 17.5 15 5.4 12.1 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Hid1 PF12722.2 ETO22197.1 - 6.7 4.2 14.0 8 4.0 9.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ycf1 PF05758.7 ETO22197.1 - 9.6 3.7 15.2 11 3.5 10.5 1.0 1 0 0 1 1 1 0 Ycf1 Piwi PF02171.12 ETO22198.1 - 8e-18 64.4 0.0 3.6e-11 42.5 0.0 2.3 2 0 0 2 2 2 2 Piwi domain DUF4299 PF14132.1 ETO22199.1 - 0.0094 15.1 0.2 0.013 14.6 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4299) Ribosomal_L6e PF01159.14 ETO22199.1 - 0.087 13.0 4.6 9.7 6.4 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein L6e IL1 PF00340.14 ETO22199.1 - 0.5 9.8 4.2 0.71 9.3 2.7 1.4 2 0 0 2 2 2 0 Interleukin-1 / 18 UQ_con PF00179.21 ETO22201.1 - 3.1e-18 65.5 0.2 6.7e-18 64.4 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PDZ PF00595.19 ETO22202.1 - 0.00019 21.5 0.0 0.0003 20.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Cylicin_N PF15241.1 ETO22202.1 - 0.11 12.3 4.3 0.19 11.5 3.0 1.4 1 0 0 1 1 1 0 Cylicin N-terminus zf-AD PF07776.10 ETO22202.1 - 0.41 10.6 2.6 0.84 9.6 1.8 1.5 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) DUF2956 PF11169.3 ETO22202.1 - 1.5 8.8 6.7 0.36 10.8 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) BLVR PF06375.6 ETO22202.1 - 5.1 6.9 15.4 0.3 10.9 5.8 2.0 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) TRF PF08558.5 ETO22203.1 - 0.018 14.3 0.2 0.14 11.4 0.0 2.1 2 0 0 2 2 2 0 Telomere repeat binding factor (TRF) Sas10_Utp3 PF04000.10 ETO22206.1 - 2.6e-08 33.9 4.1 1e-07 32.0 0.1 3.1 3 0 0 3 3 3 1 Sas10/Utp3/C1D family Aa_trans PF01490.13 ETO22207.1 - 6.7e-56 189.5 34.8 1e-55 188.9 24.1 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 ETO22207.1 - 0.00031 19.6 9.9 0.00031 19.6 6.8 2.3 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family DUF1153 PF06627.6 ETO22207.1 - 0.17 11.7 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1153) Pox_A14 PF05767.7 ETO22207.1 - 0.6 10.1 7.5 31 4.5 0.1 4.5 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 SAM_1 PF00536.25 ETO22208.1 - 0.00034 20.7 0.2 0.00034 20.7 0.1 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO22208.1 - 0.0054 16.5 0.1 0.0096 15.7 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF2785 PF10978.3 ETO22208.1 - 0.044 13.2 0.3 0.056 12.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2785) DUF512 PF04459.7 ETO22210.1 - 0.086 11.9 0.2 0.17 10.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF512) Glyco_transf_25 PF01755.12 ETO22211.1 - 0.00034 20.3 3.4 0.051 13.2 0.1 2.8 3 0 0 3 3 3 2 Glycosyltransferase family 25 (LPS biosynthesis protein) RabGAP-TBC PF00566.13 ETO22213.1 - 2.9e-07 30.1 0.1 3.7e-07 29.8 0.1 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Glyco_hydro_47 PF01532.15 ETO22214.1 - 2.9e-45 154.7 0.5 3.4e-45 154.5 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 WD40 PF00400.27 ETO22216.1 - 2.4e-44 147.6 5.7 1.4e-14 53.3 0.6 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO22216.1 - 0.0001 20.6 0.3 0.015 13.4 0.0 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO22216.1 - 0.00017 21.3 0.0 0.077 12.7 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO22216.1 - 0.00019 20.9 0.0 1.9 8.2 0.0 3.3 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 ETO22216.1 - 0.0014 17.8 1.3 0.66 9.0 0.1 2.5 1 1 2 3 3 3 2 Protein of unknown function (DUF1258) Proteasome_A_N PF10584.4 ETO22216.1 - 0.03 13.6 0.1 6.6 6.1 0.0 2.6 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature DUF3354 PF11834.3 ETO22216.1 - 0.041 13.4 0.0 0.26 10.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3354) WD40 PF00400.27 ETO22217.1 - 8.9e-15 53.9 0.0 4.8e-09 35.7 0.0 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat AGT PF11440.3 ETO22217.1 - 0.03 13.1 0.2 0.037 12.9 0.1 1.1 1 0 0 1 1 1 0 DNA alpha-glucosyltransferase PD40 PF07676.7 ETO22217.1 - 0.11 12.1 0.2 1 9.1 0.0 2.3 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Afi1 PF07792.7 ETO22217.1 - 0.32 11.0 3.6 0.47 10.4 2.5 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Pyrophosphatase PF00719.14 ETO22218.1 - 1.6e-47 160.8 0.0 1.9e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase Actin PF00022.14 ETO22220.1 - 2.1e-148 493.9 0.0 2.4e-148 493.7 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 ETO22220.1 - 0.1 13.0 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Talin_middle PF09141.5 ETO22221.1 - 0.0045 16.6 3.1 0.0077 15.9 2.2 1.3 1 0 0 1 1 1 1 Talin, middle domain DUF3439 PF11921.3 ETO22221.1 - 0.2 11.4 8.5 4.1 7.1 4.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 ETO22221.1 - 1.5 6.4 9.8 2.7 5.6 6.8 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein B56 PF01603.15 ETO22222.1 - 1.6e-63 214.7 1.5 1.9e-63 214.4 1.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) FKS1_dom1 PF14288.1 ETO22222.1 - 0.12 12.2 0.1 22 5.0 0.0 2.9 2 1 1 3 3 3 0 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF3440 PF11922.3 ETO22223.1 - 0.044 13.3 0.7 0.048 13.2 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) zf-DHHC PF01529.15 ETO22223.1 - 0.18 11.2 3.7 0.19 11.0 2.6 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase GIY-YIG PF01541.19 ETO22224.1 - 2e-11 44.1 0.4 2e-11 44.1 0.2 2.8 2 1 1 3 3 3 1 GIY-YIG catalytic domain T5orf172 PF10544.4 ETO22224.1 - 0.045 14.1 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 T5orf172 domain DUF2457 PF10446.4 ETO22224.1 - 0.23 10.1 20.9 0.41 9.3 14.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Med26 PF08711.6 ETO22226.1 - 0.016 14.7 0.4 3.5 7.1 0.1 2.3 2 0 0 2 2 2 0 TFIIS helical bundle-like domain Ribosomal_S15 PF00312.17 ETO22226.1 - 0.1 12.4 3.4 0.18 11.5 2.3 1.4 1 0 0 1 1 1 0 Ribosomal protein S15 SAM_2 PF07647.12 ETO22227.1 - 0.035 13.9 0.2 1.9 8.3 0.0 2.4 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) G0-G1_switch_2 PF15103.1 ETO22228.1 - 1 9.6 8.1 0.41 10.8 0.1 2.4 2 0 0 2 2 2 0 G0/G1 switch protein 2 DUF3245 PF11595.3 ETO22228.1 - 3.8 7.7 23.7 2.8 8.1 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3245) Sulfatase PF00884.18 ETO22232.1 - 3e-09 36.5 0.3 7.4e-09 35.2 0.0 1.7 2 0 0 2 2 2 1 Sulfatase Sulfatase_C PF14707.1 ETO22232.1 - 0.00092 19.5 0.3 0.0023 18.2 0.2 1.6 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase DHC_N1 PF08385.7 ETO22233.1 - 6.3e-23 80.9 1.5 7.9e-23 80.6 1.0 1.1 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 Herpes_glycop_D PF01537.12 ETO22233.1 - 0.03 14.2 0.4 0.053 13.4 0.3 1.3 1 0 0 1 1 1 0 Herpesvirus glycoprotein D/GG/GX domain zf-C2H2_4 PF13894.1 ETO22235.1 - 0.002 18.3 7.0 0.0046 17.1 0.8 3.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 ETO22235.1 - 0.0057 16.9 8.1 0.0098 16.1 0.6 3.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-Di19 PF05605.7 ETO22235.1 - 0.024 14.7 5.0 2.2 8.4 0.8 2.7 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 ETO22235.1 - 0.9 9.6 0.0 0.9 9.6 0.0 4.8 7 0 0 7 7 7 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 ETO22235.1 - 6.4 6.8 10.3 0.45 10.4 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger SNF2_N PF00176.18 ETO22236.1 - 7.7e-29 100.4 0.1 7.7e-29 100.4 0.1 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain FAM163 PF15069.1 ETO22236.1 - 4.7 7.7 7.3 16 6.0 4.9 2.0 1 1 0 1 1 1 0 FAM163 family PH_11 PF15413.1 ETO22237.1 - 1.2e-09 38.3 0.0 3.5e-09 36.9 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 ETO22237.1 - 1.8e-08 34.5 0.1 1.8e-08 34.5 0.1 2.6 4 0 0 4 4 4 1 PH domain PH_8 PF15409.1 ETO22237.1 - 0.0031 17.5 0.0 0.29 11.2 0.0 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain PXA PF02194.10 ETO22237.1 - 0.028 13.9 1.3 0.074 12.6 0.9 1.7 1 0 0 1 1 1 0 PXA domain Med2 PF11214.3 ETO22237.1 - 1.4 9.0 9.9 5.2 7.1 0.2 3.3 2 1 1 3 3 3 0 Mediator complex subunit 2 PH_2 PF08458.5 ETO22238.1 - 0.001 18.9 0.2 0.16 11.9 0.0 2.2 2 0 0 2 2 2 2 Plant pleckstrin homology-like region Mcp5_PH PF12814.2 ETO22238.1 - 0.06 13.2 0.1 0.19 11.6 0.0 1.9 1 1 1 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology U79_P34 PF03064.11 ETO22239.1 - 6.8 6.1 22.0 7.1 6.0 15.2 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF3464 PF11947.3 ETO22240.1 - 0.77 9.2 5.2 0.92 8.9 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) PEX11 PF05648.9 ETO22240.1 - 0.93 8.7 4.8 1.2 8.3 3.2 1.3 1 1 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) HrpJ PF07201.6 ETO22240.1 - 5.3 7.0 7.7 8 6.4 5.4 1.3 1 0 0 1 1 1 0 HrpJ-like domain Atrophin-1 PF03154.10 ETO22240.1 - 6.9 4.6 9.6 7.6 4.5 6.7 1.0 1 0 0 1 1 1 0 Atrophin-1 family DUF1961 PF09224.6 ETO22241.1 - 4.7e-05 22.5 28.0 14 4.7 0.1 10.0 1 1 11 13 13 13 10 Domain of unknown function (DUF1961) DUF243 PF03103.12 ETO22241.1 - 0.15 12.1 37.3 25 5.0 0.6 8.4 1 1 7 8 8 8 0 Domain of unknown function (DUF243) DUF4470 PF14737.1 ETO22242.1 - 0.038 13.7 0.1 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4470) Macoilin PF09726.4 ETO22243.1 - 3.6 5.7 8.3 4.1 5.5 5.7 1.0 1 0 0 1 1 1 0 Transmembrane protein fn3 PF00041.16 ETO22244.1 - 0.0003 20.8 0.0 0.00071 19.6 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain UPF0184 PF03670.8 ETO22245.1 - 2.1 8.5 4.8 2.4 8.4 2.7 1.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) S10_plectin PF03501.10 ETO22247.1 - 0.11 12.3 0.0 2.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Plectin/S10 domain Acyl-CoA_dh_M PF02770.14 ETO22248.1 - 1.8e-15 56.1 0.0 3.2e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 ETO22248.1 - 1.3e-12 48.2 0.0 2e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 ETO22249.1 - 1.3e-33 116.1 1.7 1.9e-33 115.6 1.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 ETO22249.1 - 7e-14 52.2 0.2 9.2e-14 51.8 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain FbpA PF05833.6 ETO22251.1 - 3.2e-29 101.8 0.1 3.9e-29 101.4 0.1 1.0 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Beach PF02138.13 ETO22253.1 - 9.3e-37 126.9 0.9 1.6e-36 126.1 0.0 1.8 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.1 ETO22253.1 - 1.4e-12 47.3 0.5 3.7e-12 46.0 0.4 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Dabb PF07876.7 ETO22254.1 - 5e-13 49.3 0.0 6.3e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain LigT_PEase PF02834.11 ETO22254.1 - 0.12 12.3 0.1 7.6 6.5 0.0 2.3 2 1 0 2 2 2 0 LigT like Phosphoesterase Chromo PF00385.19 ETO22255.1 - 8e-09 35.0 0.9 2e-08 33.7 0.6 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Herpes_Helicase PF02689.9 ETO22255.1 - 0.01 13.6 0.1 0.013 13.2 0.0 1.1 1 0 0 1 1 1 0 Helicase Mak16 PF04874.9 ETO22255.1 - 0.036 14.1 7.0 0.062 13.3 4.9 1.4 1 0 0 1 1 1 0 Mak16 protein C-terminal region SAM_2 PF07647.12 ETO22256.1 - 1e-05 25.2 0.6 4.9e-05 23.0 0.0 2.4 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO22256.1 - 0.05 13.7 0.9 0.19 11.9 0.1 2.3 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 ETO22256.1 - 0.17 11.6 0.1 0.17 11.6 0.1 2.1 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain zf-C3HC4 PF00097.20 ETO22257.1 - 1.3e-09 37.5 9.0 4.6e-09 35.7 6.2 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 ETO22257.1 - 1.4e-09 37.6 13.1 1.4e-09 37.6 7.2 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 ETO22257.1 - 1.4e-07 31.2 7.7 3.5e-07 29.9 5.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 ETO22257.1 - 2e-07 30.5 5.1 6e-07 29.0 3.5 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO22257.1 - 2.9e-07 30.4 9.2 2.9e-07 30.4 6.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO22257.1 - 5.6e-07 29.1 7.6 5.6e-07 29.1 5.3 2.3 3 0 0 3 3 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 ETO22257.1 - 5.5e-05 22.7 6.8 0.00021 20.9 4.7 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 ETO22257.1 - 0.0012 18.4 6.5 0.19 11.3 5.9 2.6 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain U-box PF04564.10 ETO22257.1 - 0.0022 17.9 0.1 0.014 15.3 0.0 2.3 2 0 0 2 2 2 1 U-box domain Rad50_zn_hook PF04423.9 ETO22257.1 - 0.0031 16.9 1.2 0.17 11.4 0.0 3.1 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-RING_3 PF14369.1 ETO22257.1 - 0.0095 15.9 1.4 0.86 9.6 0.4 2.6 2 0 0 2 2 2 1 zinc-finger zf-Apc11 PF12861.2 ETO22257.1 - 0.038 13.8 3.0 0.16 11.8 2.1 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 ETO22257.1 - 0.084 12.6 2.9 0.19 11.5 2.0 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.3 ETO22257.1 - 0.22 11.0 4.8 0.56 9.7 2.9 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.15 ETO22257.1 - 1 8.9 9.8 3.2 7.3 6.8 1.9 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-rbx1 PF12678.2 ETO22257.1 - 4 7.6 11.7 0.5 10.4 3.2 3.0 2 2 0 2 2 2 0 RING-H2 zinc finger Zn-ribbon_8 PF09723.5 ETO22257.1 - 4.6 7.2 7.5 30 4.6 4.6 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-RING_2 PF13639.1 ETO22258.1 - 5.3e-15 54.9 3.7 8e-15 54.3 2.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 ETO22258.1 - 5e-08 32.5 2.9 7.7e-08 31.9 2.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 ETO22258.1 - 1.3e-07 31.5 2.3 2.5e-07 30.7 1.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 ETO22258.1 - 2.3e-07 30.7 3.6 3.5e-07 30.1 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO22258.1 - 9.3e-07 28.4 0.9 1.3e-06 27.9 0.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO22258.1 - 0.00044 19.8 3.1 0.00076 19.0 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 ETO22258.1 - 0.045 13.2 3.4 0.075 12.5 2.4 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 ETO22258.1 - 0.15 11.8 2.5 0.33 10.8 1.8 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 ETO22258.1 - 0.17 11.6 1.2 0.61 9.8 0.1 2.4 1 1 1 2 2 2 0 RING-type zinc-finger Tom37_C PF11801.3 ETO22258.1 - 0.21 11.4 2.0 0.26 11.1 1.4 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain XPA_N PF01286.13 ETO22258.1 - 0.32 10.6 5.2 0.19 11.4 0.5 2.2 2 0 0 2 2 2 0 XPA protein N-terminal PBP1_TM PF14812.1 ETO22258.1 - 1.4 9.2 5.0 2.9 8.2 3.5 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_RNApol_7kD PF03604.8 ETO22259.1 - 0.051 13.0 3.7 1.6 8.2 0.3 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit SAM_2 PF07647.12 ETO22259.1 - 0.078 12.8 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF812 PF05667.6 ETO22259.1 - 0.15 10.5 7.9 0.12 10.8 4.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF812) DUF972 PF06156.8 ETO22259.1 - 1.2 9.5 10.1 1.1 9.6 3.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) ABA_GPCR PF12430.3 ETO22260.1 - 7.8e-17 61.0 1.7 7.8e-17 61.0 1.2 2.2 2 1 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 ETO22260.1 - 3.5e-15 55.8 0.1 1.8e-14 53.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) CENP-B_dimeris PF09026.5 ETO22261.1 - 0.021 15.0 1.1 0.038 14.2 0.8 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RXT2_N PF08595.6 ETO22261.1 - 0.14 11.9 2.1 0.25 11.1 1.4 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.8 ETO22261.1 - 0.19 11.3 2.0 0.3 10.6 1.4 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.1 ETO22261.1 - 0.23 11.7 5.2 0.45 10.8 3.6 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.4 ETO22261.1 - 0.28 9.8 7.7 0.47 9.1 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Utp13 PF08625.6 ETO22262.1 - 0.0081 15.8 0.2 0.011 15.4 0.1 1.3 1 1 0 1 1 1 1 Utp13 specific WD40 associated domain Latrotoxin_C PF15658.1 ETO22262.1 - 0.064 13.0 0.2 5.4 6.8 0.0 2.2 2 0 0 2 2 2 0 Latrotoxin C-terminal domain USP8_dimer PF08969.6 ETO22263.1 - 3.8e-08 33.2 2.5 6.3e-08 32.5 1.7 1.3 1 0 0 1 1 1 1 USP8 dimerisation domain Prothymosin PF03247.9 ETO22263.1 - 0.081 13.0 21.2 0.12 12.5 14.7 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family DUF4175 PF13779.1 ETO22263.1 - 0.19 9.3 8.0 0.21 9.2 5.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CDC45 PF02724.9 ETO22263.1 - 0.32 8.9 6.7 0.34 8.8 4.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Spore_coat_CotO PF14153.1 ETO22263.1 - 0.37 10.1 10.7 0.51 9.7 7.4 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Trypan_PARP PF05887.6 ETO22263.1 - 1.3 8.8 12.8 1.7 8.4 8.9 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Paf1 PF03985.8 ETO22263.1 - 2.7 6.6 16.2 3.4 6.3 11.2 1.1 1 0 0 1 1 1 0 Paf1 Nop53 PF07767.6 ETO22263.1 - 4.5 6.1 20.6 5.6 5.8 14.3 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) ZZ PF00569.12 ETO22264.1 - 6.3e-11 41.6 10.5 6.3e-11 41.6 7.3 3.4 2 1 0 2 2 2 1 Zinc finger, ZZ type PB1 PF00564.19 ETO22264.1 - 2.6e-07 30.2 0.0 5.8e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 PB1 domain Borrelia_P83 PF05262.6 ETO22264.1 - 0.00062 18.1 22.2 0.00062 18.1 15.4 1.6 2 0 0 2 2 2 1 Borrelia P83/100 protein SAPS PF04499.10 ETO22264.1 - 0.0015 17.3 13.3 0.0015 17.3 9.2 2.2 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein Nop14 PF04147.7 ETO22264.1 - 0.064 11.1 39.5 0.13 10.2 27.4 1.4 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 ETO22264.1 - 0.35 10.0 26.3 0.55 9.4 18.2 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Astro_capsid PF03115.9 ETO22267.1 - 0.057 11.6 4.9 0.073 11.3 3.4 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor PP2C_C PF07830.8 ETO22267.1 - 0.17 12.0 3.1 8.9 6.5 0.6 2.5 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain RP-C_C PF11800.3 ETO22267.1 - 7.2 6.2 10.6 15 5.2 7.3 1.6 1 1 0 1 1 1 0 Replication protein C C-terminal region PHD PF00628.24 ETO22269.1 - 7.8e-05 22.2 3.3 7.8e-05 22.2 2.3 2.2 2 0 0 2 2 2 1 PHD-finger Pox_H7 PF04787.7 ETO22270.1 - 0.019 14.7 1.3 0.022 14.5 0.9 1.2 1 0 0 1 1 1 0 Late protein H7 Glyco_hydro_70 PF02324.11 ETO22270.1 - 0.032 12.0 0.4 0.035 11.8 0.3 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 XH PF03469.9 ETO22270.1 - 0.075 12.6 4.8 0.087 12.4 3.1 1.3 1 1 0 1 1 1 0 XH domain CaMBD PF02888.11 ETO22270.1 - 0.1 12.4 0.5 0.21 11.4 0.3 1.7 1 1 0 1 1 1 0 Calmodulin binding domain DUF2407_C PF13373.1 ETO22270.1 - 0.1 12.5 0.5 0.12 12.3 0.3 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain MPP6 PF10175.4 ETO22271.1 - 0.019 15.3 0.7 0.019 15.3 0.5 2.3 2 1 0 2 2 2 0 M-phase phosphoprotein 6 RNase_PH_C PF03725.10 ETO22271.1 - 0.065 13.1 0.1 15 5.5 0.1 2.5 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 Asp PF00026.18 ETO22272.1 - 5.2e-40 137.6 14.0 3.7e-39 134.8 9.7 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETO22272.1 - 4e-09 36.6 0.4 6.8e-07 29.3 0.0 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 ETO22272.1 - 0.00049 19.6 0.1 0.00099 18.6 0.1 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 ETO22272.1 - 0.015 15.8 1.2 8 7.0 0.0 3.8 2 2 1 4 4 4 0 Aspartyl protease DUF4480 PF13715.1 ETO22273.1 - 0.0089 16.0 2.4 0.012 15.6 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4480) CarboxypepD_reg PF13620.1 ETO22273.1 - 0.047 13.7 0.7 0.16 12.0 0.1 2.2 2 1 1 3 3 3 0 Carboxypeptidase regulatory-like domain DUF4634 PF15465.1 ETO22273.1 - 0.062 13.5 0.0 0.12 12.5 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4634) TPR_12 PF13424.1 ETO22274.1 - 3.2e-36 123.1 0.3 5.2e-14 51.9 0.1 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO22274.1 - 4.2e-22 77.5 3.1 9.9e-12 44.3 0.0 3.3 2 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETO22274.1 - 2e-18 65.1 9.9 3.9e-09 35.7 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO22274.1 - 3.6e-18 63.9 4.8 7.1e-07 28.6 0.0 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO22274.1 - 2.2e-17 61.3 0.8 3.5e-07 29.5 0.0 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO22274.1 - 4.1e-16 58.3 0.0 1.8e-06 27.6 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO22274.1 - 4.5e-13 47.9 9.0 2.1e-06 27.1 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO22274.1 - 6.3e-05 22.8 7.7 0.00087 19.3 0.2 5.1 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO22274.1 - 0.0002 21.6 1.0 0.12 12.8 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO22274.1 - 0.0002 21.4 2.9 0.1 12.7 0.1 3.2 1 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.1 ETO22274.1 - 0.00024 20.3 0.2 0.074 12.1 0.0 2.4 2 0 0 2 2 2 2 Soluble NSF attachment protein, SNAP PPR PF01535.15 ETO22274.1 - 0.00098 18.9 0.1 3.1 7.9 0.0 3.8 4 0 0 4 4 4 1 PPR repeat DUF2225 PF09986.4 ETO22274.1 - 0.0011 18.4 0.8 0.0061 16.0 0.1 2.5 1 1 2 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_14 PF13428.1 ETO22274.1 - 0.0035 17.8 0.0 0.39 11.4 0.0 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO22274.1 - 0.026 15.1 0.0 6.1 7.6 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETO22274.1 - 0.089 13.1 0.1 0.33 11.3 0.0 2.0 2 0 0 2 2 1 0 Tetratricopeptide repeat WD40 PF00400.27 ETO22275.1 - 4.8e-35 118.1 13.1 6.6e-13 47.9 0.0 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO22275.1 - 6.7e-12 44.3 0.8 6.5e-07 27.8 0.2 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 CENP-F_leu_zip PF10473.4 ETO22276.1 - 6e-07 29.4 21.6 6e-07 29.4 15.0 1.8 2 0 0 2 2 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MAD PF05557.8 ETO22276.1 - 0.00018 19.7 24.8 0.00025 19.3 17.2 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF4164 PF13747.1 ETO22276.1 - 0.0022 18.0 15.4 0.0053 16.8 5.2 2.8 1 1 2 3 3 3 1 Domain of unknown function (DUF4164) ABC2_membrane_3 PF12698.2 ETO22276.1 - 0.0093 15.0 2.7 0.01 14.8 1.9 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF4140 PF13600.1 ETO22276.1 - 0.011 16.1 19.6 0.13 12.7 1.0 3.4 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) Myosin_tail_1 PF01576.14 ETO22276.1 - 0.023 12.4 24.3 0.019 12.7 15.1 1.5 1 1 0 1 1 1 0 Myosin tail Reo_sigmaC PF04582.7 ETO22276.1 - 0.034 13.3 11.2 0.045 12.9 2.9 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF724 PF05266.9 ETO22276.1 - 0.14 11.7 20.0 0.2 11.2 12.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Filament PF00038.16 ETO22276.1 - 0.16 11.4 22.6 0.75 9.2 5.9 2.1 1 1 1 2 2 2 0 Intermediate filament protein Atg14 PF10186.4 ETO22276.1 - 0.16 10.8 20.6 0.28 10.1 14.3 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1664 PF07889.7 ETO22276.1 - 0.18 11.5 14.6 0.61 9.8 4.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.17 ETO22276.1 - 0.33 10.9 28.4 0.11 12.4 6.6 2.6 2 1 1 3 3 2 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.6 ETO22276.1 - 0.36 9.4 26.5 0.35 9.4 6.6 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein HrpB7 PF09486.5 ETO22276.1 - 0.37 10.6 15.2 0.26 11.2 7.7 2.6 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) IncA PF04156.9 ETO22276.1 - 0.41 10.2 30.7 5.1 6.6 21.0 2.2 1 1 0 1 1 1 0 IncA protein TMF_TATA_bd PF12325.3 ETO22276.1 - 0.45 10.2 22.1 2.2 8.0 5.5 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.3 ETO22276.1 - 0.45 10.4 33.5 1.9 8.3 8.9 2.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding AAA_13 PF13166.1 ETO22276.1 - 0.47 8.8 26.6 0.34 9.3 17.4 1.5 1 1 1 2 2 2 0 AAA domain Coat_F PF07875.7 ETO22276.1 - 0.49 10.5 6.0 0.35 11.0 1.5 2.6 3 0 0 3 3 2 0 Coat F domain COG2 PF06148.6 ETO22276.1 - 0.5 10.2 14.7 0.53 10.1 2.0 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TMCO5 PF14992.1 ETO22276.1 - 0.59 9.2 23.2 0.039 13.0 12.7 1.5 2 0 0 2 2 1 0 TMCO5 family Nup54 PF13874.1 ETO22276.1 - 0.65 9.6 23.8 0.08 12.6 9.8 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 HlyD PF00529.15 ETO22276.1 - 0.77 9.0 29.9 1.4 8.1 20.7 1.4 1 1 0 1 1 1 0 HlyD family secretion protein ATG16 PF08614.6 ETO22276.1 - 1.6 8.5 34.2 0.045 13.5 11.3 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) APG6 PF04111.7 ETO22276.1 - 1.7 7.6 31.1 0.16 10.9 18.2 1.8 2 1 0 2 2 1 0 Autophagy protein Apg6 Macoilin PF09726.4 ETO22276.1 - 1.7 6.8 26.1 2.2 6.4 18.1 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4200 PF13863.1 ETO22276.1 - 1.8 8.4 30.4 0.081 12.8 14.2 2.6 2 1 1 3 3 2 0 Domain of unknown function (DUF4200) PspA_IM30 PF04012.7 ETO22276.1 - 2.7 7.2 25.0 4.9 6.4 7.4 2.5 1 1 0 2 2 2 0 PspA/IM30 family Ax_dynein_light PF10211.4 ETO22276.1 - 3.5 7.4 30.8 0.025 14.4 11.0 3.3 2 1 2 4 4 3 0 Axonemal dynein light chain DivIC PF04977.10 ETO22276.1 - 4 7.0 34.5 1.1 8.7 2.2 4.6 1 1 3 4 4 4 0 Septum formation initiator Allexi_40kDa PF05549.6 ETO22276.1 - 4.1 6.6 15.6 0.87 8.8 6.4 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein Mnd1 PF03962.10 ETO22276.1 - 4.5 6.8 29.9 2.5 7.6 4.1 2.7 1 1 1 2 2 2 0 Mnd1 family Noelin-1 PF12308.3 ETO22276.1 - 5 6.9 13.3 0.32 10.8 2.7 2.4 1 1 1 2 2 2 0 Neurogenesis glycoprotein V_ATPase_I PF01496.14 ETO22276.1 - 5.5 4.7 23.2 7 4.3 15.7 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family GAS PF13851.1 ETO22276.1 - 5.5 6.1 30.4 0.25 10.4 10.1 2.3 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding ERM PF00769.14 ETO22276.1 - 5.8 6.3 30.9 1.7 8.1 15.3 2.6 2 1 1 3 3 3 0 Ezrin/radixin/moesin family Jnk-SapK_ap_N PF09744.4 ETO22276.1 - 6.8 6.6 16.8 15 5.5 10.7 2.0 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF4446 PF14584.1 ETO22276.1 - 8.3 6.2 14.2 8 6.2 1.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) bZIP_1 PF00170.16 ETO22276.1 - 8.4 6.4 22.8 2.3 8.2 0.4 4.1 1 1 3 4 4 4 0 bZIP transcription factor FlaC_arch PF05377.6 ETO22276.1 - 8.6 6.3 11.1 72 3.3 3.6 3.6 2 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF3450 PF11932.3 ETO22276.1 - 8.8 5.5 26.2 0.085 12.1 7.5 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Vfa1 PF08432.5 ETO22276.1 - 9.4 6.2 22.2 1.6 8.7 9.2 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 CENP-F_leu_zip PF10473.4 ETO22277.1 - 3.9e-07 30.0 44.3 2.7e-06 27.2 16.5 3.0 2 1 1 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.4 ETO22277.1 - 0.00011 21.2 20.3 0.00011 21.2 14.1 2.3 2 1 1 3 3 2 1 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 ETO22277.1 - 0.00034 20.2 36.7 0.0033 17.0 12.3 2.7 2 1 1 3 3 3 2 IncA protein Filament PF00038.16 ETO22277.1 - 0.00034 20.1 32.4 0.12 11.8 4.5 3.1 2 1 1 3 3 3 2 Intermediate filament protein Tropomyosin_1 PF12718.2 ETO22277.1 - 0.002 17.9 37.8 0.0027 17.5 8.8 3.7 2 1 1 3 3 3 2 Tropomyosin like TMCO5 PF14992.1 ETO22277.1 - 0.003 16.7 13.3 0.003 16.7 9.2 1.8 2 0 0 2 2 2 1 TMCO5 family DUF972 PF06156.8 ETO22277.1 - 0.0034 17.7 30.5 1.2 9.5 4.3 3.9 2 1 2 4 4 4 2 Protein of unknown function (DUF972) CALCOCO1 PF07888.6 ETO22277.1 - 0.0051 15.1 19.6 0.0082 14.4 13.6 1.3 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like MT PF12777.2 ETO22277.1 - 0.0059 15.4 2.0 0.0059 15.4 1.4 2.3 1 1 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_13 PF13166.1 ETO22277.1 - 0.0064 15.0 28.1 0.02 13.4 19.5 1.8 1 1 0 1 1 1 1 AAA domain WEMBL PF05701.6 ETO22277.1 - 0.008 14.6 26.7 0.1 11.0 18.7 2.1 1 1 0 1 1 1 1 Weak chloroplast movement under blue light APG6 PF04111.7 ETO22277.1 - 0.0084 15.1 17.4 0.0084 15.1 12.0 2.6 2 1 1 3 3 3 1 Autophagy protein Apg6 Myosin_tail_1 PF01576.14 ETO22277.1 - 0.015 13.0 26.7 0.042 11.5 18.5 1.7 1 1 0 1 1 1 0 Myosin tail Cortex-I_coil PF09304.5 ETO22277.1 - 0.016 15.2 10.7 0.016 15.2 7.4 3.3 2 1 2 4 4 3 0 Cortexillin I, coiled coil Striatin PF08232.7 ETO22277.1 - 0.021 15.1 26.3 0.84 9.9 9.2 3.0 1 1 1 2 2 2 0 Striatin family Reo_sigmaC PF04582.7 ETO22277.1 - 0.022 13.9 12.4 0.043 13.0 4.7 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 ETO22277.1 - 0.023 14.5 46.3 0.031 14.0 4.3 4.3 3 1 0 4 4 4 0 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.16 ETO22277.1 - 0.024 14.5 29.7 0.037 13.9 2.1 5.4 2 1 3 5 5 4 0 bZIP transcription factor EzrA PF06160.7 ETO22277.1 - 0.028 12.6 26.0 0.089 10.9 18.0 1.7 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA TMPIT PF07851.8 ETO22277.1 - 0.029 13.4 12.7 0.059 12.4 8.8 1.5 1 0 0 1 1 1 0 TMPIT-like protein CCDC155 PF14662.1 ETO22277.1 - 0.032 13.8 33.3 1.3 8.5 19.9 3.3 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 Leu_zip PF15294.1 ETO22277.1 - 0.036 13.1 31.1 0.014 14.5 12.5 2.9 2 1 1 3 3 3 0 Leucine zipper ADIP PF11559.3 ETO22277.1 - 0.037 13.9 42.5 0.039 13.8 13.6 3.2 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.3 ETO22277.1 - 0.038 13.2 29.7 0.048 12.9 12.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TSC22 PF01166.13 ETO22277.1 - 0.039 13.9 22.3 0.73 9.8 0.8 4.8 2 1 3 5 5 5 0 TSC-22/dip/bun family FUSC PF04632.7 ETO22277.1 - 0.04 12.3 0.7 0.051 12.0 0.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Spc7 PF08317.6 ETO22277.1 - 0.041 12.5 34.1 0.23 10.0 6.3 2.4 2 1 1 3 3 3 0 Spc7 kinetochore protein AAA_27 PF13514.1 ETO22277.1 - 0.053 11.2 21.2 0.073 10.7 14.7 1.2 1 0 0 1 1 1 0 AAA domain Cast PF10174.4 ETO22277.1 - 0.06 11.4 26.3 0.1 10.6 12.3 2.0 1 1 1 2 2 2 0 RIM-binding protein of the cytomatrix active zone ERM PF00769.14 ETO22277.1 - 0.062 12.8 34.3 0.0097 15.4 19.6 2.2 2 1 0 2 2 1 0 Ezrin/radixin/moesin family Nup54 PF13874.1 ETO22277.1 - 0.063 12.9 26.7 0.016 14.8 11.4 2.3 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 GAS PF13851.1 ETO22277.1 - 0.066 12.3 37.4 0.17 11.0 9.6 3.0 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding LMBR1 PF04791.11 ETO22277.1 - 0.083 11.4 7.0 0.12 10.9 4.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DivIC PF04977.10 ETO22277.1 - 0.13 11.7 36.8 0.12 11.8 4.6 4.7 2 1 2 4 4 4 0 Septum formation initiator LPP PF04728.8 ETO22277.1 - 0.14 11.9 12.5 0.82 9.5 1.2 2.9 2 1 0 2 2 2 0 Lipoprotein leucine-zipper TMF_TATA_bd PF12325.3 ETO22277.1 - 0.18 11.5 29.0 0.048 13.3 2.5 3.2 2 1 2 4 4 3 0 TATA element modulatory factor 1 TATA binding DUF869 PF05911.6 ETO22277.1 - 0.21 9.7 28.7 0.11 10.6 2.5 2.7 2 1 1 3 3 3 0 Plant protein of unknown function (DUF869) DUF904 PF06005.7 ETO22277.1 - 0.31 11.3 42.7 0.07 13.4 6.5 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF904) DUF1664 PF07889.7 ETO22277.1 - 0.33 10.7 16.6 0.55 10.0 4.6 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) HrpB7 PF09486.5 ETO22277.1 - 0.34 10.8 16.1 0.093 12.6 1.2 3.1 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) TPR_MLP1_2 PF07926.7 ETO22277.1 - 0.41 10.3 40.1 0.46 10.2 14.4 3.0 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Kinesin-relat_1 PF12711.2 ETO22277.1 - 0.42 11.0 24.8 0.2 12.0 2.5 3.1 2 1 0 3 3 2 0 Kinesin motor TBPIP PF07106.8 ETO22277.1 - 0.44 10.0 35.5 0.073 12.6 12.5 3.6 2 1 2 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Seryl_tRNA_N PF02403.17 ETO22277.1 - 0.88 9.6 32.0 1.6 8.7 1.8 3.7 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain PspA_IM30 PF04012.7 ETO22277.1 - 0.88 8.8 30.8 0.13 11.5 9.6 2.5 2 1 1 3 3 2 0 PspA/IM30 family Lebercilin PF15619.1 ETO22277.1 - 0.92 8.8 35.8 0.11 11.8 10.4 3.2 2 1 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease bZIP_2 PF07716.10 ETO22277.1 - 1.1 9.1 27.4 1.1 9.1 1.7 5.2 3 2 2 5 5 4 0 Basic region leucine zipper Mod_r PF07200.8 ETO22277.1 - 1.5 8.7 31.3 0.47 10.3 9.7 3.0 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF3584 PF12128.3 ETO22277.1 - 1.6 5.9 29.0 5 4.3 20.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4446 PF14584.1 ETO22277.1 - 1.7 8.4 21.4 1.4 8.7 1.5 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF4446) Prefoldin_2 PF01920.15 ETO22277.1 - 2.1 8.1 39.5 0.22 11.3 5.3 4.3 2 1 3 5 5 5 0 Prefoldin subunit Exonuc_VII_L PF02601.10 ETO22277.1 - 2.5 7.2 20.3 3.7 6.6 14.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DivIVA PF05103.8 ETO22277.1 - 2.7 8.0 34.1 0.33 11.0 1.8 3.4 2 1 0 3 3 3 0 DivIVA protein ATG16 PF08614.6 ETO22277.1 - 2.8 7.7 35.8 0.65 9.7 14.0 2.6 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) FliJ PF02050.11 ETO22277.1 - 2.9 7.9 33.7 0.5 10.4 7.0 3.4 2 1 2 4 4 3 0 Flagellar FliJ protein V-ATPase_C PF03223.10 ETO22277.1 - 3.1 6.6 21.6 0.14 11.0 8.1 2.5 1 1 1 2 2 2 0 V-ATPase subunit C HOOK PF05622.7 ETO22277.1 - 3.2 5.4 31.1 0.2 9.4 14.8 2.2 2 1 1 3 3 3 0 HOOK protein DUF4140 PF13600.1 ETO22277.1 - 3.3 8.1 24.9 1 9.8 2.1 3.6 2 1 1 4 4 3 0 N-terminal domain of unknown function (DUF4140) Sec20 PF03908.8 ETO22277.1 - 3.5 7.4 18.5 1.4 8.6 6.8 3.5 2 1 1 3 3 2 0 Sec20 IFT57 PF10498.4 ETO22277.1 - 3.5 6.2 33.8 2.3 6.8 20.7 2.2 2 1 0 2 2 1 0 Intra-flagellar transport protein 57 Sec8_exocyst PF04048.9 ETO22277.1 - 4.2 7.0 21.6 13 5.3 11.8 2.9 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain Golgin_A5 PF09787.4 ETO22277.1 - 4.3 5.7 29.2 2.4 6.6 18.0 2.0 2 1 0 2 2 2 0 Golgin subfamily A member 5 DUF1515 PF07439.6 ETO22277.1 - 4.5 7.1 9.1 8.9 6.1 0.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) COG5 PF10392.4 ETO22277.1 - 4.7 7.1 20.1 1.2 9.0 9.2 2.3 1 1 1 2 2 2 0 Golgi transport complex subunit 5 CP12 PF02672.10 ETO22277.1 - 4.8 7.7 10.8 8.3 6.9 2.6 2.8 1 1 0 2 2 2 0 CP12 domain HAUS-augmin3 PF14932.1 ETO22277.1 - 4.9 6.2 27.4 1.6 7.8 13.4 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Laminin_I PF06008.9 ETO22277.1 - 5.1 6.3 31.0 2.2 7.5 12.4 2.1 1 1 1 2 2 2 0 Laminin Domain I DUF3708 PF12501.3 ETO22277.1 - 5.5 6.7 5.1 12 5.7 3.1 1.9 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter BLOC1_2 PF10046.4 ETO22277.1 - 5.5 7.1 29.3 0.61 10.2 9.9 2.8 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4201 PF13870.1 ETO22277.1 - 5.7 6.3 28.9 13 5.1 6.3 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) MAD PF05557.8 ETO22277.1 - 7.2 4.5 36.3 0.29 9.1 20.9 1.6 2 0 0 2 2 2 0 Mitotic checkpoint protein Bacillus_HBL PF05791.6 ETO22277.1 - 8.4 5.7 26.3 0.048 13.0 7.6 3.1 2 1 2 4 4 3 0 Bacillus haemolytic enterotoxin (HBL) Cluap1 PF10234.4 ETO22277.1 - 8.7 5.4 28.2 5.9 6.0 4.9 2.5 1 1 1 2 2 2 0 Clusterin-associated protein-1 DUF812 PF05667.6 ETO22277.1 - 9.3 4.6 31.3 1.3 7.4 18.6 1.7 2 1 0 2 2 1 0 Protein of unknown function (DUF812) HAP1_N PF04849.8 ETO22277.1 - 9.7 5.0 33.2 4.3 6.1 17.8 2.6 2 1 1 3 3 3 0 HAP1 N-terminal conserved region 7tm_1 PF00001.16 ETO22278.1 - 0.053 12.6 2.0 0.053 12.6 1.4 1.2 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Exostosin PF03016.10 ETO22279.1 - 5.4e-14 51.9 0.0 8.7e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Exostosin family ETRAMP PF09716.5 ETO22280.1 - 0.085 12.8 1.5 0.17 11.8 1.0 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) WD40 PF00400.27 ETO22281.1 - 3.9e-17 61.4 2.0 2e-09 36.9 0.0 3.2 3 1 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO22281.1 - 6.3e-05 21.2 0.1 0.062 11.4 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 WD40 PF00400.27 ETO22282.1 - 4.2e-11 42.2 3.5 6.5e-11 41.6 2.4 1.3 1 0 0 1 1 1 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO22282.1 - 0.0075 14.4 0.2 0.0079 14.3 0.1 1.0 1 0 0 1 1 1 1 Nucleoporin Nup120/160 DUF3099 PF11298.3 ETO22282.1 - 0.6 9.8 5.7 0.62 9.8 3.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3099) Tenui_PVC2 PF06656.6 ETO22282.1 - 3.3 5.3 7.0 3.8 5.1 4.8 1.2 1 0 0 1 1 1 0 Tenuivirus PVC2 protein EXS PF03124.9 ETO22283.1 - 1e-33 116.8 35.8 6.5e-30 104.3 12.3 3.1 1 1 2 3 3 3 2 EXS family SPX PF03105.14 ETO22283.1 - 3.9e-06 26.8 36.9 0.02 14.7 25.5 3.0 2 1 0 2 2 2 1 SPX domain TPR_11 PF13414.1 ETO22284.1 - 3.7e-05 23.2 9.9 0.047 13.3 4.0 2.7 1 1 2 3 3 3 3 TPR repeat TPR_16 PF13432.1 ETO22284.1 - 0.00016 22.2 1.0 0.0043 17.6 0.2 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO22284.1 - 0.00064 20.0 3.9 0.033 14.5 0.3 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO22284.1 - 0.0063 17.0 2.3 0.22 12.2 0.0 3.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO22284.1 - 0.011 15.4 4.3 3 7.8 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETO22284.1 - 0.025 14.4 12.6 1.9 8.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETO22284.1 - 0.1 12.5 11.9 0.086 12.7 1.8 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETO22284.1 - 0.14 11.8 6.6 1.4 8.6 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETO22284.1 - 0.27 11.0 11.6 2.4 8.1 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 ETO22284.1 - 4.8 7.6 6.1 15 6.1 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Vps54 PF07928.7 ETO22285.1 - 3.3e-30 104.9 5.3 3.3e-30 104.9 3.7 2.3 2 0 0 2 2 2 1 Vps54-like protein Exonuc_VII_L PF02601.10 ETO22286.1 - 0.12 11.5 5.9 0.28 10.3 4.1 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF1302 PF06980.6 ETO22287.1 - 0.018 13.6 0.9 0.025 13.1 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1302) ubiquitin PF00240.18 ETO22288.1 - 0.054 12.8 0.2 0.1 11.9 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin family DUF307 PF03733.8 ETO22288.1 - 0.2 12.0 3.6 0.42 11.0 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF307) Macro PF01661.16 ETO22289.1 - 2.1e-13 50.1 0.3 1.6e-05 24.7 0.0 3.1 1 1 1 2 2 2 2 Macro domain MA3 PF02847.12 ETO22291.1 - 3e-11 43.0 2.4 4.4e-07 29.5 0.1 2.5 2 0 0 2 2 2 2 MA3 domain DUF1488 PF07369.6 ETO22291.1 - 0.023 14.5 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1488) PXA PF02194.10 ETO22291.1 - 0.089 12.3 2.0 0.18 11.3 0.1 2.4 1 1 2 3 3 3 0 PXA domain Podoplanin PF05808.6 ETO22291.1 - 1.1 8.7 5.3 1.8 8.1 3.7 1.3 1 0 0 1 1 1 0 Podoplanin DUF4604 PF15377.1 ETO22291.1 - 1.3 9.2 13.7 2 8.5 9.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) adh_short PF00106.20 ETO22293.1 - 0.03 14.2 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase HAD_2 PF13419.1 ETO22294.1 - 6.3e-06 26.5 0.0 1e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Peptidase_S49_N PF08496.5 ETO22294.1 - 3.1 7.5 4.8 63 3.3 0.0 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Kelch_6 PF13964.1 ETO22295.1 - 0.046 13.9 0.8 0.14 12.3 0.1 2.3 2 0 0 2 2 2 0 Kelch motif DUF1981 PF09324.5 ETO22296.1 - 2.4e-22 78.2 1.7 2.4e-22 78.2 1.2 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) DUF3484 PF11983.3 ETO22297.1 - 0.035 14.9 0.6 0.088 13.6 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3484) DUF1627 PF07789.7 ETO22297.1 - 0.066 12.7 0.0 0.16 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1627) Sec7_N PF12783.2 ETO22298.1 - 5.9e-32 110.4 0.5 5.9e-32 110.4 0.4 1.4 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Daxx PF03344.10 ETO22299.1 - 0.24 9.8 12.9 0.24 9.8 9.0 1.0 1 0 0 1 1 1 0 Daxx Family V_ATPase_I PF01496.14 ETO22299.1 - 0.92 7.2 5.3 1 7.1 3.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Senescence_reg PF04520.8 ETO22299.1 - 5.6 7.4 9.8 8.3 6.8 6.8 1.2 1 0 0 1 1 1 0 Senescence regulator AAA_18 PF13238.1 ETO22300.1 - 2.2e-05 24.7 0.6 8.8e-05 22.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETO22300.1 - 0.00022 21.3 0.1 0.0011 19.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain RelA_SpoT PF04607.12 ETO22300.1 - 0.00061 19.7 1.1 0.00061 19.7 0.8 2.4 2 1 0 2 2 2 1 Region found in RelA / SpoT proteins AAA_17 PF13207.1 ETO22300.1 - 0.00094 19.9 0.1 0.0052 17.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 ETO22300.1 - 0.0015 18.2 0.0 0.0078 15.8 0.0 2.2 2 0 0 2 2 2 1 NACHT domain KaiC PF06745.8 ETO22300.1 - 0.011 14.9 1.2 1.2 8.2 0.0 3.1 3 0 0 3 3 3 0 KaiC UPF0079 PF02367.12 ETO22300.1 - 0.026 14.1 0.0 0.063 12.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 ETO22300.1 - 0.029 14.2 0.0 0.091 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 ETO22300.1 - 0.036 14.2 0.0 0.16 12.1 0.0 2.2 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 ETO22300.1 - 0.065 13.5 0.0 0.3 11.3 0.0 2.2 1 0 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.21 ETO22300.1 - 0.075 12.5 0.0 0.29 10.5 0.0 2.0 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.1 ETO22300.1 - 0.097 12.2 0.0 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain DIE2_ALG10 PF04922.7 ETO22301.1 - 8.7e-23 80.9 9.6 8.7e-23 80.9 6.7 1.9 2 0 0 2 2 2 1 DIE2/ALG10 family DUF1748 PF08520.5 ETO22301.1 - 0.025 14.2 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1748) DAGK_acc PF00609.14 ETO22302.1 - 2.2e-19 70.1 0.1 1.1e-18 67.9 0.0 2.1 2 0 0 2 2 2 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 ETO22302.1 - 4.6e-14 51.9 0.0 8.4e-14 51.1 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain APC10 PF03256.11 ETO22303.1 - 1.5e-51 174.7 0.5 2e-51 174.3 0.3 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 ETO22303.1 - 0.0032 17.3 0.1 0.0069 16.2 0.0 1.6 1 0 0 1 1 1 1 F5/8 type C domain Arm PF00514.18 ETO22304.1 - 1.8e-17 62.4 4.2 0.0027 17.4 0.2 6.3 6 0 0 6 6 6 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 ETO22304.1 - 5.1e-05 23.4 0.0 0.091 13.0 0.0 2.5 2 0 0 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 ETO22304.1 - 7.8e-05 23.0 1.1 0.022 15.2 0.1 3.5 3 1 1 4 4 4 1 HEAT-like repeat Nop14 PF04147.7 ETO22304.1 - 8.8 4.1 7.8 13 3.5 4.4 1.8 2 0 0 2 2 2 0 Nop14-like family Ribosomal_60s PF00428.14 ETO22304.1 - 9.3 6.7 10.9 28 5.1 7.5 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3439 PF11921.3 ETO22305.1 - 0.59 9.8 8.3 1.5 8.6 5.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Zip PF02535.17 ETO22305.1 - 2.7 6.9 6.1 6.2 5.7 4.3 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Ycf1 PF05758.7 ETO22306.1 - 2.1e-05 22.4 6.2 2.6e-05 22.1 4.3 1.1 1 0 0 1 1 1 1 Ycf1 TFIIF_alpha PF05793.7 ETO22306.1 - 0.049 12.0 25.7 0.064 11.6 17.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) IncA PF04156.9 ETO22306.1 - 0.14 11.7 10.1 0.28 10.7 7.0 1.5 1 1 0 1 1 1 0 IncA protein DHC PF09626.5 ETO22306.1 - 0.15 12.7 1.1 0.53 10.9 0.2 2.1 2 1 0 2 2 2 0 Dihaem cytochrome c GPCR_chapero_1 PF11904.3 ETO22306.1 - 0.37 9.8 9.3 0.27 10.3 5.5 1.4 2 0 0 2 2 2 0 GPCR-chaperone Nop14 PF04147.7 ETO22306.1 - 0.62 7.9 25.7 0.15 9.9 15.8 1.3 2 0 0 2 2 2 0 Nop14-like family GAGA_bind PF06217.7 ETO22306.1 - 2.1 8.2 7.6 3 7.7 5.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF572 PF04502.8 ETO22306.1 - 3.2 6.8 20.2 4.6 6.3 14.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) BTV_NS2 PF04514.7 ETO22306.1 - 4.8 5.9 16.8 6.8 5.4 11.7 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Sec62 PF03839.11 ETO22306.1 - 6.1 6.1 19.0 10 5.4 13.1 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 FLO_LFY PF01698.11 ETO22306.1 - 6.9 5.4 12.2 9.5 4.9 8.5 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein CT47 PF15623.1 ETO22306.1 - 7.1 6.2 22.8 9.7 5.8 15.8 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 Ion_trans PF00520.26 ETO22307.1 - 1e-21 77.1 63.5 9.8e-20 70.6 17.4 3.9 3 1 1 4 4 4 3 Ion transport protein EF-hand_6 PF13405.1 ETO22307.1 - 0.0011 18.7 0.7 0.51 10.3 0.3 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 ETO22307.1 - 0.0082 15.3 1.7 0.73 9.2 0.5 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 ETO22307.1 - 0.019 15.0 2.0 0.48 10.6 0.3 2.7 2 1 1 3 3 3 0 EF-hand domain pair DUF1744 PF08490.7 ETO22308.1 - 2.4e-16 59.3 0.7 2.6e-16 59.2 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) UCH PF00443.24 ETO22309.1 - 5.2e-07 29.0 0.0 7.3e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 ETO22310.1 - 0.0044 16.1 0.6 0.0052 15.9 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Drf_FH3 PF06367.11 ETO22310.1 - 0.05 13.0 5.0 0.14 11.5 2.0 1.9 1 1 1 2 2 2 0 Diaphanous FH3 Domain NRN1 PF15056.1 ETO22310.1 - 0.12 12.2 0.7 0.25 11.3 0.1 1.8 2 0 0 2 2 2 0 Neuritin protein family FKBP_N PF01346.13 ETO22310.1 - 1.1 9.2 10.8 0.54 10.3 2.7 2.1 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase IncA PF04156.9 ETO22310.1 - 2.5 7.6 7.7 3.6 7.1 5.3 1.2 1 0 0 1 1 1 0 IncA protein DUF1662 PF07878.6 ETO22311.1 - 0.0027 17.3 0.1 0.04 13.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1662) CAAP1 PF15335.1 ETO22311.1 - 0.019 15.1 0.1 0.033 14.3 0.1 1.4 1 0 0 1 1 1 0 Caspase activity and apoptosis inhibitor 1 TPR_11 PF13414.1 ETO22311.1 - 0.091 12.4 4.0 0.18 11.5 1.4 2.1 1 1 1 2 2 2 0 TPR repeat PRP38_assoc PF12871.2 ETO22312.1 - 3.1e-08 34.0 26.6 5.5e-08 33.2 18.5 1.5 1 0 0 1 1 1 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Surp PF01805.15 ETO22312.1 - 7.5e-07 28.7 0.0 1.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Surp module DUF1777 PF08648.7 ETO22312.1 - 1.6e-06 27.9 19.3 2.4e-06 27.4 13.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) YL1 PF05764.8 ETO22312.1 - 0.041 13.5 12.1 0.06 12.9 8.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Renin_r PF07850.9 ETO22312.1 - 0.081 13.2 2.9 0.15 12.4 2.0 1.5 1 0 0 1 1 1 0 Renin receptor-like protein CDC45 PF02724.9 ETO22312.1 - 1.8 6.5 11.6 2.1 6.2 8.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Rifin_STEVOR PF02009.11 ETO22312.1 - 3.6 7.1 7.8 5.6 6.5 5.4 1.2 1 0 0 1 1 1 0 Rifin/stevor family U1snRNP70_N PF12220.3 ETO22313.1 - 0.7 10.2 18.2 0.57 10.5 1.2 3.2 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF2203 PF09969.4 ETO22313.1 - 2.4 8.3 7.1 1.6 8.9 2.4 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) PPP4R2 PF09184.6 ETO22314.1 - 0.0028 17.2 17.3 0.0033 17.0 12.0 1.1 1 0 0 1 1 1 1 PPP4R2 CDC27 PF09507.5 ETO22314.1 - 0.024 13.8 31.4 0.025 13.8 21.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 HhH-GPD PF00730.20 ETO22314.1 - 0.03 14.6 0.1 0.077 13.2 0.1 1.9 1 1 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein MIP-T3 PF10243.4 ETO22314.1 - 0.41 9.0 37.8 0.47 8.8 26.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Nucleo_P87 PF07267.6 ETO22314.1 - 1.4 7.5 15.1 1.6 7.3 10.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Na_trans_assoc PF06512.8 ETO22314.1 - 1.6 8.6 21.5 1.9 8.3 14.9 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Zip PF02535.17 ETO22314.1 - 2.4 7.0 6.8 3.2 6.6 4.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Mucin PF01456.12 ETO22314.1 - 3.3 7.4 10.7 4.6 6.9 7.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein HAUS6_N PF14661.1 ETO22314.1 - 4.7 6.4 17.8 6.4 6.0 12.3 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Asp-B-Hydro_N PF05279.6 ETO22314.1 - 6.7 6.4 24.4 7.1 6.4 16.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Ycf1 PF05758.7 ETO22314.1 - 9.5 3.7 19.0 12 3.4 13.2 1.2 1 0 0 1 1 1 0 Ycf1 RGS PF00615.14 ETO22315.1 - 0.0019 18.3 0.4 0.0021 18.1 0.3 1.3 1 1 0 1 1 1 1 Regulator of G protein signaling domain LAM_C PF12544.3 ETO22316.1 - 2.1 8.4 6.7 2.1 8.4 4.6 1.0 1 0 0 1 1 1 0 Lysine-2,3-aminomutase AAA_12 PF13087.1 ETO22317.1 - 3.7e-34 117.8 0.0 7.6e-34 116.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Radial_spoke_3 PF06098.6 ETO22318.1 - 9.6e-26 90.4 16.6 2.1e-25 89.3 11.5 1.5 1 0 0 1 1 1 1 Radial spoke protein 3 Orbi_NS3 PF01616.11 ETO22318.1 - 1.1 8.2 9.4 0.055 12.4 1.7 2.3 2 1 0 2 2 2 0 Orbivirus NS3 Ion_trans PF00520.26 ETO22320.1 - 6.8e-69 231.1 58.3 6.4e-33 113.6 14.7 4.2 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.7 ETO22320.1 - 1.8e-05 23.3 13.3 1.8e-05 23.3 9.2 5.9 5 2 2 7 7 7 4 Polycystin cation channel DUF1179 PF06678.6 ETO22320.1 - 0.18 12.1 0.5 1.7 8.9 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) Mucin PF01456.12 ETO22321.1 - 0.002 17.9 2.9 0.002 17.9 2.0 2.3 2 0 0 2 2 2 1 Mucin-like glycoprotein Mid2 PF04478.7 ETO22321.1 - 0.0092 15.4 9.0 0.024 14.0 0.1 2.8 3 0 0 3 3 3 1 Mid2 like cell wall stress sensor Shisa PF13908.1 ETO22321.1 - 0.029 14.5 0.8 0.066 13.3 0.5 1.7 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Adeno_E3_CR2 PF02439.10 ETO22321.1 - 0.04 13.4 0.7 0.04 13.4 0.5 1.9 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 DUF3439 PF11921.3 ETO22321.1 - 0.045 13.5 4.6 0.13 12.0 3.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TrmE_N PF10396.4 ETO22321.1 - 0.063 13.2 0.3 8.7 6.3 0.0 2.3 2 0 0 2 2 2 0 GTP-binding protein TrmE N-terminus SBF2 PF12335.3 ETO22321.1 - 0.31 10.3 2.7 8.9 5.5 0.1 2.2 2 0 0 2 2 2 0 Myotubularin protein TMEM154 PF15102.1 ETO22321.1 - 0.51 10.0 5.6 4 7.1 0.0 2.5 2 0 0 2 2 2 0 TMEM154 protein family Topo_Zn_Ribbon PF08272.6 ETO22322.1 - 0.5 9.7 3.6 0.77 9.1 0.2 2.4 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like Porin_4 PF13609.1 ETO22324.1 - 8.4e-05 22.2 1.8 0.00011 21.8 1.3 1.3 1 0 0 1 1 1 1 Gram-negative porin OMP_b-brl PF13505.1 ETO22324.1 - 0.0061 16.5 12.1 0.0082 16.1 5.5 2.4 1 1 0 2 2 2 1 Outer membrane protein beta-barrel domain OmpA_membrane PF01389.12 ETO22324.1 - 0.018 14.5 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 OmpA-like transmembrane domain vATP-synt_AC39 PF01992.11 ETO22325.1 - 2.3e-13 50.0 2.7 3.5e-08 32.9 1.2 3.0 2 1 0 2 2 2 2 ATP synthase (C/AC39) subunit DUF1548 PF07579.6 ETO22326.1 - 0.0073 16.4 0.6 0.013 15.6 0.4 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1548) EST1 PF10374.4 ETO22326.1 - 0.16 11.9 3.2 0.12 12.3 0.7 1.9 2 1 0 2 2 2 0 Telomerase activating protein Est1 ZZ PF00569.12 ETO22326.1 - 0.3 10.6 7.3 1.3 8.6 5.1 1.9 1 1 0 1 1 1 0 Zinc finger, ZZ type Vps51 PF08700.6 ETO22326.1 - 1.1 9.1 4.3 1.1 9.1 0.2 2.4 3 0 0 3 3 3 0 Vps51/Vps67 DUF4428 PF14471.1 ETO22326.1 - 1.7 8.4 10.9 4.4 7.1 4.7 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4428) LRR_8 PF13855.1 ETO22328.1 - 8.4e-25 86.3 32.6 2.6e-08 33.4 6.7 6.6 1 1 6 7 7 7 7 Leucine rich repeat LRR_4 PF12799.2 ETO22328.1 - 1.9e-23 81.5 41.2 2.1e-06 27.2 4.1 8.0 1 1 9 10 10 10 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETO22328.1 - 1.6e-19 66.9 32.4 0.011 15.6 0.3 11.7 10 1 1 11 11 11 8 Leucine Rich Repeat LRR_6 PF13516.1 ETO22328.1 - 2.4e-05 23.9 39.4 0.28 11.3 0.3 10.5 8 4 4 12 12 12 4 Leucine Rich repeat LRR_7 PF13504.1 ETO22328.1 - 0.0001 21.9 28.7 9.2 6.9 0.0 11.2 11 0 0 11 11 11 1 Leucine rich repeat LRRNT_2 PF08263.7 ETO22328.1 - 0.016 15.1 1.3 0.049 13.6 0.9 1.9 1 1 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_8 PF13855.1 ETO22329.1 - 6.9e-07 28.9 27.6 0.00014 21.5 1.8 4.6 2 1 4 6 6 6 4 Leucine rich repeat LRR_4 PF12799.2 ETO22329.1 - 5.6e-06 25.8 31.1 0.0042 16.6 6.7 5.0 3 1 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETO22329.1 - 0.013 15.4 36.2 1.6 9.0 0.2 9.3 10 0 0 10 10 10 0 Leucine Rich Repeat LRR_7 PF13504.1 ETO22329.1 - 0.12 12.6 27.7 8.4 7.0 0.1 8.1 9 0 0 9 9 9 0 Leucine rich repeat IF-2B PF01008.12 ETO22330.1 - 1.7e-16 60.0 0.4 6.6e-14 51.5 0.0 2.2 2 0 0 2 2 2 2 Initiation factor 2 subunit family Symplekin_C PF12295.3 ETO22330.1 - 0.00026 20.9 0.2 0.001 19.0 0.0 2.0 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal DUF569 PF04601.8 ETO22331.1 - 0.011 15.1 0.1 0.019 14.3 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF569) RicinB_lectin_2 PF14200.1 ETO22331.1 - 0.015 15.6 0.2 0.26 11.7 0.0 2.4 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like DUF2306 PF10067.4 ETO22332.1 - 0.036 14.1 0.2 0.036 14.1 0.2 2.7 2 1 0 3 3 3 0 Predicted membrane protein (DUF2306) BTB PF00651.26 ETO22333.1 - 3.8e-12 46.1 0.1 9.5e-12 44.8 0.1 1.7 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 ETO22333.1 - 0.086 12.6 5.1 0.92 9.3 0.6 3.3 3 0 0 3 3 3 0 BTB And C-terminal Kelch Secretin_N_2 PF07655.8 ETO22333.1 - 0.39 11.1 13.6 0.76 10.2 9.4 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Menin PF05053.8 ETO22333.1 - 4.3 5.3 8.0 6.5 4.7 5.5 1.2 1 0 0 1 1 1 0 Menin IstB_IS21 PF01695.12 ETO22336.1 - 0.061 12.7 0.0 0.16 11.3 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF445 PF04286.7 ETO22338.1 - 2.3e-07 30.7 0.4 0.0026 17.3 0.0 3.1 3 1 1 4 4 4 2 Protein of unknown function (DUF445) DUF3816 PF12822.2 ETO22338.1 - 0.019 14.8 8.7 0.21 11.4 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3816) GET2 PF08690.5 ETO22338.1 - 0.35 10.0 6.1 0.18 11.0 0.6 2.4 1 1 1 2 2 2 0 GET complex subunit GET2 WD40 PF00400.27 ETO22339.1 - 6.3e-10 38.5 6.7 0.1 12.5 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat CENP-T PF15511.1 ETO22340.1 - 0.099 11.8 19.0 0.12 11.5 13.2 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Pilt PF15453.1 ETO22340.1 - 0.33 10.5 9.5 0.39 10.3 6.6 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Hid1 PF12722.2 ETO22340.1 - 0.93 7.0 21.5 1.1 6.8 14.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Daxx PF03344.10 ETO22340.1 - 1.2 7.5 34.6 1.5 7.2 24.0 1.2 1 0 0 1 1 1 0 Daxx Family DUF605 PF04652.11 ETO22340.1 - 2 7.7 23.4 2.2 7.6 16.2 1.1 1 0 0 1 1 1 0 Vta1 like SAPS PF04499.10 ETO22340.1 - 2.8 6.4 17.0 4.2 5.8 11.8 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Utp14 PF04615.8 ETO22340.1 - 7.3 4.6 29.5 9.3 4.2 20.5 1.1 1 0 0 1 1 1 0 Utp14 protein DUF1136 PF06582.7 ETO22341.1 - 0.033 13.8 0.9 4.5 7.0 0.1 2.6 2 0 0 2 2 2 0 Repeat of unknown function (DUF1136) DUF4200 PF13863.1 ETO22341.1 - 0.14 12.1 36.7 0.037 13.9 15.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Beta_protein PF14350.1 ETO22341.1 - 0.14 11.3 5.3 0.19 10.8 3.7 1.3 1 0 0 1 1 1 0 Beta protein LMBR1 PF04791.11 ETO22341.1 - 2 6.8 6.6 2.2 6.7 4.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein YtxH PF12732.2 ETO22341.1 - 2.2 8.7 12.5 0.33 11.3 1.9 2.7 1 1 1 2 2 2 0 YtxH-like protein ApoO PF09769.4 ETO22341.1 - 5.3 6.7 7.5 7.7 6.2 0.5 2.3 1 1 1 2 2 2 0 Apolipoprotein O DUF4241 PF14025.1 ETO22341.1 - 7.9 6.2 10.8 8 6.1 4.4 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF4241) Arfaptin PF06456.8 ETO22342.1 - 0.031 13.6 0.7 0.052 12.8 0.5 1.3 1 0 0 1 1 1 0 Arfaptin-like domain Macoilin PF09726.4 ETO22342.1 - 0.12 10.6 21.2 0.14 10.4 14.7 1.0 1 0 0 1 1 1 0 Transmembrane protein CHAT PF12770.2 ETO22343.1 - 3.9e-08 32.7 0.0 1.4e-07 30.9 0.0 1.8 1 1 0 1 1 1 1 CHAT domain NACHT PF05729.7 ETO22343.1 - 7.1e-05 22.5 0.0 0.00023 20.8 0.0 1.9 1 0 0 1 1 1 1 NACHT domain Ion_trans PF00520.26 ETO22344.1 - 1e-36 126.0 16.2 1.6e-36 125.4 11.2 1.3 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.7 ETO22344.1 - 3.2e-06 25.8 10.2 5.5e-06 25.0 7.1 1.4 1 0 0 1 1 1 1 Polycystin cation channel Arm PF00514.18 ETO22347.1 - 0.0024 17.6 0.8 0.022 14.5 0.0 2.5 2 1 0 2 2 2 1 Armadillo/beta-catenin-like repeat Arm PF00514.18 ETO22348.1 - 3.8e-10 39.2 4.7 0.00045 19.9 0.2 3.9 3 0 0 3 3 3 3 Armadillo/beta-catenin-like repeat zf-TRAF PF02176.13 ETO22349.1 - 1.8e-05 25.0 0.4 7.4e-05 23.0 0.1 2.2 2 0 0 2 2 2 1 TRAF-type zinc finger APG6 PF04111.7 ETO22350.1 - 2.5e-55 187.7 1.5 3e-55 187.4 1.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg6 DUF1664 PF07889.7 ETO22350.1 - 0.00046 19.9 2.7 0.00075 19.2 1.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) DUF972 PF06156.8 ETO22350.1 - 0.0007 19.9 2.1 0.0015 18.8 1.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF972) HAP1_N PF04849.8 ETO22350.1 - 0.003 16.5 5.3 0.0046 15.9 3.7 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DUF342 PF03961.8 ETO22350.1 - 0.033 12.6 0.6 0.044 12.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CENP-F_leu_zip PF10473.4 ETO22350.1 - 0.04 13.7 10.3 0.47 10.3 6.7 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.17 ETO22350.1 - 0.066 13.2 2.5 0.12 12.3 1.7 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF3166 PF11365.3 ETO22350.1 - 0.068 13.6 6.4 0.16 12.4 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) Rootletin PF15035.1 ETO22350.1 - 0.078 12.9 4.4 0.12 12.3 3.0 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Snapin_Pallidin PF14712.1 ETO22350.1 - 0.091 13.0 4.4 0.19 12.0 3.1 1.6 1 0 0 1 1 1 0 Snapin/Pallidin Tektin PF03148.9 ETO22350.1 - 0.13 10.8 5.0 0.28 9.7 3.4 1.6 1 1 0 1 1 1 0 Tektin family Spc7 PF08317.6 ETO22350.1 - 0.22 10.1 4.0 0.31 9.6 2.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.10 ETO22350.1 - 0.33 10.4 5.4 0.42 10.1 1.6 2.2 2 0 0 2 2 2 0 Septum formation initiator Atg14 PF10186.4 ETO22350.1 - 0.78 8.6 4.3 1.3 7.8 3.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF904 PF06005.7 ETO22350.1 - 0.79 10.0 6.0 1.5 9.1 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Cep57_MT_bd PF06657.8 ETO22350.1 - 0.99 9.3 8.1 0.22 11.5 2.8 1.9 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 IncA PF04156.9 ETO22350.1 - 1.1 8.7 6.8 1.6 8.2 4.7 1.2 1 0 0 1 1 1 0 IncA protein DUF4140 PF13600.1 ETO22350.1 - 1.7 9.1 3.9 2.8 8.4 1.1 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4164 PF13747.1 ETO22350.1 - 3 8.0 8.1 4.4 7.5 3.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) bZIP_1 PF00170.16 ETO22350.1 - 3.2 7.7 7.7 1.1 9.2 3.1 1.9 2 0 0 2 2 2 0 bZIP transcription factor AMP-binding PF00501.23 ETO22351.1 - 6.5e-26 90.6 0.3 2e-12 46.2 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 ETO22351.1 - 6.8e-15 55.7 0.1 1.2e-14 54.9 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DENN PF02141.16 ETO22352.1 - 0.012 15.3 0.1 0.026 14.2 0.1 1.6 1 0 0 1 1 1 0 DENN (AEX-3) domain AAA_22 PF13401.1 ETO22355.1 - 0.00033 20.7 0.0 0.0076 16.3 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 ETO22356.1 - 6.5e-06 25.9 0.1 3.8e-05 23.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 ETO22356.1 - 7.6e-06 26.1 0.3 1.2e-05 25.4 0.2 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 ETO22356.1 - 0.00019 21.7 0.3 0.00029 21.1 0.2 1.4 1 1 0 1 1 1 1 ABC transporter AAA_14 PF13173.1 ETO22356.1 - 0.00049 19.9 0.7 0.0011 18.9 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETO22356.1 - 0.0013 19.0 1.2 0.0034 17.6 0.9 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 ETO22356.1 - 0.0024 17.0 0.0 1.3 8.1 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_23 PF13476.1 ETO22356.1 - 0.0032 17.8 2.1 0.0061 16.9 1.5 1.5 1 1 0 1 1 1 1 AAA domain MCM PF00493.18 ETO22356.1 - 0.015 14.1 0.1 0.031 13.0 0.0 1.5 2 0 0 2 2 2 0 MCM2/3/5 family DUF815 PF05673.8 ETO22356.1 - 0.024 13.5 0.1 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.1 ETO22356.1 - 0.027 14.4 0.3 0.13 12.2 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 ETO22356.1 - 0.028 14.5 0.8 0.18 11.9 0.4 2.0 1 1 1 2 2 2 0 AAA domain AAA_8 PF12780.2 ETO22356.1 - 0.034 13.1 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 Sigma54_activat PF00158.21 ETO22356.1 - 0.034 13.6 0.0 0.15 11.5 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_17 PF13207.1 ETO22356.1 - 0.037 14.8 2.1 0.73 10.6 1.5 2.2 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 ETO22356.1 - 0.082 12.5 1.1 0.23 11.0 0.7 2.1 1 1 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 ETO22356.1 - 0.093 12.3 0.3 0.28 10.8 0.2 1.8 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 ETO22356.1 - 0.11 12.1 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_2 PF07724.9 ETO22356.1 - 0.14 12.0 0.6 1.1 9.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 ETO22356.1 - 0.15 12.2 0.4 0.43 10.7 0.2 1.9 1 1 0 1 1 1 0 RNA helicase ATP-synt_ab PF00006.20 ETO22356.1 - 0.2 11.1 0.4 0.49 9.8 0.2 1.5 1 1 1 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.1 ETO22356.1 - 0.22 11.1 1.6 0.32 10.5 0.4 1.9 2 1 0 2 2 2 0 AAA domain SMC_N PF02463.14 ETO22356.1 - 0.25 10.5 1.6 1 8.5 0.0 2.4 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain DUF87 PF01935.12 ETO22356.1 - 0.68 9.7 3.2 3.7 7.3 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function DUF87 HSP70 PF00012.15 ETO22357.1 - 1.9e-49 168.1 0.4 1.9e-49 168.1 0.3 1.7 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 ETO22357.1 - 2.2e-09 36.3 0.6 3.8e-09 35.6 0.4 1.3 1 0 0 1 1 1 1 MreB/Mbl protein HK97-gp10_like PF04883.7 ETO22357.1 - 0.31 11.9 2.5 12 6.8 0.0 3.1 3 0 0 3 3 3 0 Bacteriophage HK97-gp10, putative tail-component BTV_NS2 PF04514.7 ETO22358.1 - 2.7 6.7 14.6 2.9 6.6 10.1 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 LptE PF04390.7 ETO22358.1 - 4.4 7.0 8.6 1.2 8.8 0.9 2.3 1 1 1 2 2 2 0 Lipopolysaccharide-assembly Repressor_Mnt PF11423.3 ETO22358.1 - 6.4 6.1 10.5 26 4.2 0.1 3.6 1 1 2 3 3 3 0 Regulatory protein Mnt Daxx PF03344.10 ETO22358.1 - 7.3 4.9 22.0 8.4 4.7 15.2 1.0 1 0 0 1 1 1 0 Daxx Family DUF2151 PF10221.4 ETO22358.1 - 9.1 4.3 6.8 10 4.1 4.7 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Alkyl_sulf_dimr PF14863.1 ETO22360.1 - 7e-07 29.5 0.1 1.3e-06 28.7 0.1 1.4 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Alkyl_sulf_C PF14864.1 ETO22360.1 - 5.5e-05 23.1 0.1 0.00052 19.9 0.0 2.5 2 1 0 2 2 2 1 Alkyl sulfatase C-terminal Reticulon PF02453.12 ETO22361.1 - 0.016 14.8 0.2 0.029 13.9 0.2 1.4 1 0 0 1 1 1 0 Reticulon Conotoxin PF02950.12 ETO22361.1 - 0.31 11.8 0.1 0.31 11.8 0.1 2.1 2 0 0 2 2 2 0 Conotoxin TMEM171 PF15471.1 ETO22361.1 - 0.68 8.6 4.8 1 8.0 3.3 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Mem_trans PF03547.13 ETO22361.1 - 7.9 4.6 8.7 4.2 5.5 4.4 1.7 1 1 1 2 2 2 0 Membrane transport protein FAM178 PF14816.1 ETO22362.1 - 0.051 12.2 1.1 0.063 11.9 0.6 1.3 1 1 0 1 1 1 0 Family of unknown function, FAM178 zf-UBP PF02148.14 ETO22363.1 - 4.2e-16 58.8 10.8 4.2e-16 58.8 7.5 2.8 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein BRAP2 PF07576.7 ETO22363.1 - 4.3e-16 58.4 1.3 4.3e-16 58.4 0.9 2.3 2 0 0 2 2 2 1 BRCA1-associated protein 2 zf-RING_2 PF13639.1 ETO22363.1 - 2e-06 27.5 1.5 2e-06 27.5 1.1 3.5 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO22363.1 - 0.0053 16.7 2.9 0.0053 16.7 2.0 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Ald_Xan_dh_C2 PF02738.13 ETO22363.1 - 0.012 14.0 0.1 0.018 13.3 0.1 1.2 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase RRM_1 PF00076.17 ETO22363.1 - 0.063 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PolC_DP2 PF03833.8 ETO22363.1 - 0.11 10.1 3.3 0.18 9.4 2.3 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF3610 PF12272.3 ETO22364.1 - 0.026 14.1 0.4 0.026 14.1 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3610) CENP-B_dimeris PF09026.5 ETO22365.1 - 0.092 12.9 4.4 3.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain FMO-like PF00743.14 ETO22366.1 - 3.7e-15 55.1 0.0 4.5e-15 54.8 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 ETO22366.1 - 1.8e-07 31.4 0.0 2.2e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETO22366.1 - 5e-07 29.6 0.1 8.4e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETO22366.1 - 0.00017 20.6 0.0 0.0031 16.4 0.1 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 ETO22366.1 - 0.00038 20.2 0.1 0.0012 18.6 0.0 1.8 1 1 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.12 ETO22366.1 - 0.0055 15.8 0.0 0.0081 15.2 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 ETO22366.1 - 0.0068 16.3 0.0 0.015 15.2 0.0 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETO22366.1 - 0.02 15.2 0.0 0.036 14.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETO22366.1 - 0.024 13.4 0.1 0.032 13.0 0.1 1.1 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.19 ETO22366.1 - 0.036 13.1 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase K_oxygenase PF13434.1 ETO22366.1 - 0.045 12.6 0.2 4.5 6.1 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 ETO22366.1 - 0.095 11.7 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 ETO22366.1 - 0.15 10.5 0.0 0.22 9.9 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FMO-like PF00743.14 ETO22367.1 - 2.7e-06 25.8 0.0 3.2e-06 25.6 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 ETO22368.1 - 0.0002 21.5 0.0 0.00026 21.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETO22368.1 - 0.0012 17.0 0.0 0.0012 17.0 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Shikimate_DH PF01488.15 ETO22368.1 - 0.0034 17.4 0.0 0.004 17.2 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 ETO22368.1 - 0.057 13.8 0.0 0.092 13.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Aldo_ket_red PF00248.16 ETO22369.1 - 1.1e-17 63.7 0.0 1.2e-17 63.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3912 PF13051.1 ETO22369.1 - 0.05 13.3 0.2 0.08 12.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3912) Lipoxygenase PF00305.14 ETO22369.1 - 0.058 11.3 0.2 0.064 11.2 0.1 1.0 1 0 0 1 1 1 0 Lipoxygenase Aldo_ket_red PF00248.16 ETO22370.1 - 1e-27 96.7 0.0 1.2e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family F-box PF00646.28 ETO22371.1 - 2e-07 30.4 0.8 3.7e-07 29.6 0.5 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 ETO22371.1 - 2e-05 24.2 0.9 4.1e-05 23.1 0.6 1.5 1 0 0 1 1 1 1 F-box-like Pex14_N PF04695.8 ETO22371.1 - 0.0092 16.0 13.0 0.032 14.2 6.2 2.1 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2201_N PF13203.1 ETO22371.1 - 0.023 13.9 14.4 0.49 9.5 4.9 2.1 2 0 0 2 2 2 0 Putative metallopeptidase domain SpoVR PF04293.8 ETO22371.1 - 0.031 12.6 10.4 0.053 11.8 7.2 1.3 1 0 0 1 1 1 0 SpoVR like protein Borrelia_P83 PF05262.6 ETO22371.1 - 0.042 12.1 8.9 0.064 11.5 6.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Ctr PF04145.10 ETO22371.1 - 0.049 13.6 2.7 0.27 11.2 1.0 2.2 2 0 0 2 2 2 0 Ctr copper transporter family DUF4484 PF14831.1 ETO22371.1 - 0.064 13.3 6.5 0.25 11.4 2.3 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4484) CDC45 PF02724.9 ETO22371.1 - 0.21 9.5 10.9 0.0072 14.4 3.6 1.4 2 0 0 2 2 2 0 CDC45-like protein Suf PF05843.9 ETO22371.1 - 0.43 10.2 20.5 0.14 11.8 12.3 1.5 1 1 1 2 2 2 0 Suppressor of forked protein (Suf) AAA_23 PF13476.1 ETO22371.1 - 0.85 9.9 15.2 1.3 9.3 10.5 1.3 1 0 0 1 1 1 0 AAA domain Dala_Dala_lig_N PF01820.16 ETO22371.1 - 3 8.1 6.3 1.5 9.1 2.5 1.8 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus Vfa1 PF08432.5 ETO22371.1 - 3.2 7.7 18.5 0.13 12.2 7.8 1.9 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Myb_DNA-binding PF00249.26 ETO22372.1 - 4.3e-20 71.5 4.5 2.4e-11 43.4 0.4 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 ETO22372.1 - 4.7e-17 61.8 9.2 3.9e-14 52.4 3.7 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.3 ETO22372.1 - 0.077 12.8 1.0 1.1 9.1 0.1 2.2 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain RRM_1 PF00076.17 ETO22373.1 - 2.6e-18 65.4 0.1 2.4e-11 43.0 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO22373.1 - 3e-14 52.7 0.0 1.8e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO22373.1 - 4.9e-11 42.3 0.2 0.00027 20.7 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 ETO22373.1 - 0.00053 19.7 0.2 0.0014 18.4 0.1 1.7 1 1 1 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 ETO22373.1 - 0.0031 17.2 0.1 0.038 13.7 0.0 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.6 ETO22373.1 - 0.0067 16.3 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 RNA binding domain DUF3882 PF07066.6 ETO22374.1 - 0.039 13.8 0.5 0.052 13.3 0.3 1.2 1 0 0 1 1 1 0 Lactococcus phage M3 protein IBD PF10416.4 ETO22374.1 - 0.62 9.8 5.5 1 9.1 3.8 1.4 1 0 0 1 1 1 0 Transcription-initiator DNA-binding domain IBD PRP38_assoc PF12871.2 ETO22375.1 - 0.00067 20.1 45.1 0.00067 20.1 31.3 3.3 2 2 0 2 2 2 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term GASA PF02704.9 ETO22375.1 - 0.042 13.8 2.3 0.1 12.5 1.6 1.6 1 0 0 1 1 1 0 Gibberellin regulated protein Methyltransf_12 PF08242.7 ETO22376.1 - 1.8 9.0 6.9 36 4.9 0.0 3.1 3 1 0 3 3 3 0 Methyltransferase domain CMAS PF02353.15 ETO22377.1 - 0.023 13.7 0.5 0.041 12.9 0.3 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF3439 PF11921.3 ETO22377.1 - 0.64 9.7 11.3 1.2 8.8 7.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Pkinase PF00069.20 ETO22378.1 - 3.4e-56 190.2 0.0 6.3e-56 189.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO22378.1 - 1.5e-25 89.7 0.0 3.1e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_I PF08311.7 ETO22378.1 - 3.2e-09 36.6 6.2 6.2e-09 35.7 4.3 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 APH PF01636.18 ETO22378.1 - 0.0014 18.4 0.0 0.037 13.7 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 ETO22378.1 - 0.0029 16.6 0.0 0.0052 15.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Daxx PF03344.10 ETO22378.1 - 0.0034 15.9 36.4 0.0049 15.4 25.2 1.1 1 0 0 1 1 1 1 Daxx Family RIO1 PF01163.17 ETO22378.1 - 0.0035 16.6 0.0 0.01 15.1 0.0 1.8 1 0 0 1 1 1 1 RIO1 family TPR_19 PF14559.1 ETO22378.1 - 0.018 15.3 0.1 0.23 11.8 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat Mucin PF01456.12 ETO22378.1 - 3.3 7.4 17.2 6 6.6 11.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein PYRIN PF02758.11 ETO22379.1 - 0.015 14.9 1.5 0.015 14.9 1.1 1.7 2 0 0 2 2 2 0 PAAD/DAPIN/Pyrin domain DUF2681 PF10883.3 ETO22379.1 - 5.5 7.2 11.9 0.51 10.5 2.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2681) Pkinase PF00069.20 ETO22380.1 - 3.7e-22 78.7 0.0 3.7e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO22380.1 - 5.8e-11 41.9 0.0 7.1e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 ETO22380.1 - 6.5e-05 22.6 0.2 0.00018 21.1 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kinase-like PF14531.1 ETO22380.1 - 0.00042 19.3 0.0 0.00057 18.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETO22380.1 - 0.021 13.9 0.0 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lipoprotein_19 PF13617.1 ETO22380.1 - 0.19 11.4 1.2 0.33 10.6 0.8 1.4 1 0 0 1 1 1 0 YnbE-like lipoprotein Chorion_2 PF03964.10 ETO22381.1 - 0.0063 17.0 2.2 0.012 16.1 1.5 1.4 1 0 0 1 1 1 1 Chorion family 2 SSP160 PF06933.6 ETO22381.1 - 1.6 6.6 12.9 1.9 6.3 8.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Macoilin PF09726.4 ETO22381.1 - 3.8 5.6 11.2 4.9 5.3 7.8 1.2 1 0 0 1 1 1 0 Transmembrane protein SR-25 PF10500.4 ETO22381.1 - 4 6.8 25.8 0.86 9.0 11.7 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4547 PF15080.1 ETO22382.1 - 0.00029 20.3 0.1 0.0013 18.2 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4547) DUF2457 PF10446.4 ETO22382.1 - 0.0063 15.3 18.0 0.0063 15.3 12.5 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF2457) CENP-T PF15511.1 ETO22382.1 - 0.94 8.6 24.9 2.1 7.4 7.4 2.2 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T NOA36 PF06524.7 ETO22382.1 - 4.7 6.3 34.7 4.4 6.4 9.3 2.5 2 0 0 2 2 2 0 NOA36 protein Ebola_NP PF05505.7 ETO22382.1 - 5.5 4.9 35.5 3.3 5.6 9.7 2.1 2 0 0 2 2 2 0 Ebola nucleoprotein OTU PF02338.14 ETO22383.1 - 0.0002 21.9 0.2 0.0013 19.3 0.0 2.3 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 ETO22383.1 - 0.00027 20.3 1.7 0.00044 19.6 0.3 2.0 2 0 0 2 2 2 1 Peptidase C65 Otubain TFIIF_alpha PF05793.7 ETO22383.1 - 0.0074 14.7 12.9 0.01 14.2 9.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.9 ETO22383.1 - 0.021 12.9 7.3 0.025 12.6 5.0 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF605 PF04652.11 ETO22383.1 - 6.9 5.9 17.7 29 3.8 0.0 2.1 2 0 0 2 2 2 0 Vta1 like Limkain-b1 PF11608.3 ETO22384.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 RTTN_N PF14726.1 ETO22386.1 - 0.096 13.2 3.2 10 6.8 0.7 3.5 3 1 0 3 3 3 0 Rotatin, an armadillo repeat protein, centriole functioning EF1_GNE PF00736.14 ETO22386.1 - 0.12 12.1 0.0 0.64 9.7 0.0 2.2 1 1 1 2 2 2 0 EF-1 guanine nucleotide exchange domain Baculo_11_kDa PF06143.6 ETO22387.1 - 0.06 12.7 0.1 0.06 12.7 0.1 4.6 5 0 0 5 5 5 0 Baculovirus 11 kDa family Peroxin-13_N PF04088.8 ETO22387.1 - 0.31 10.9 2.8 1.2 9.0 0.2 2.4 2 0 0 2 2 2 0 Peroxin 13, N-terminal region DUF3353 PF11833.3 ETO22387.1 - 2.9 7.2 5.5 8.4 5.8 3.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) Trp_halogenase PF04820.9 ETO22388.1 - 0.13 10.8 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase RNase_PH PF01138.16 ETO22389.1 - 6.7e-24 84.6 0.0 1.5e-23 83.5 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 ETO22389.1 - 0.01 15.7 0.1 0.027 14.3 0.0 1.7 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 CBS PF00571.23 ETO22390.1 - 3e-15 55.7 0.1 6.1e-08 32.3 0.0 2.7 3 0 0 3 3 3 2 CBS domain PspB PF06667.7 ETO22391.1 - 0.021 14.7 0.5 0.043 13.7 0.3 1.5 1 0 0 1 1 1 0 Phage shock protein B Chlam_PMP PF02415.12 ETO22391.1 - 2.1 8.8 4.4 1.4 9.3 0.4 2.7 2 1 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat CENP-T PF15511.1 ETO22391.1 - 5.7 6.0 16.4 7.3 5.7 11.4 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Daxx PF03344.10 ETO22391.1 - 7.4 4.9 19.3 9.5 4.5 13.4 1.1 1 0 0 1 1 1 0 Daxx Family Hid1 PF12722.2 ETO22391.1 - 8.8 3.8 10.9 10 3.6 7.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CCDC-167 PF15188.1 ETO22392.1 - 0.069 13.1 3.1 0.33 10.9 1.1 2.8 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 PI3_PI4_kinase PF00454.22 ETO22393.1 - 0.0014 18.1 1.7 0.0023 17.4 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase XPA_C PF05181.7 ETO22395.1 - 6.7e-08 31.9 3.2 1.3e-05 24.6 0.6 2.8 2 0 0 2 2 2 2 XPA protein C-terminus TBCC PF07986.7 ETO22395.1 - 0.029 13.7 0.2 0.029 13.7 0.1 1.6 2 0 0 2 2 2 0 Tubulin binding cofactor C BCL_N PF04714.8 ETO22395.1 - 0.033 13.7 1.8 0.033 13.7 1.3 1.9 2 0 0 2 2 2 0 BCL7, N-terminal conserver region RelA_SpoT PF04607.12 ETO22395.1 - 0.034 14.1 1.0 0.056 13.4 0.1 1.9 1 1 1 2 2 2 0 Region found in RelA / SpoT proteins 5_3_exonuc PF01367.15 ETO22395.1 - 0.082 13.1 0.5 0.18 12.0 0.1 1.8 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold XPA_N PF01286.13 ETO22395.1 - 0.097 12.3 1.3 0.22 11.2 0.1 2.1 2 0 0 2 2 2 0 XPA protein N-terminal DUF3116 PF11313.3 ETO22395.1 - 0.11 12.1 0.2 0.24 11.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3116) zf-CCCH PF00642.19 ETO22396.1 - 8.5e-08 31.6 4.3 1.3e-07 31.1 3.0 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Osmo_CC PF08946.5 ETO22396.1 - 0.0049 16.8 1.7 0.01 15.8 1.2 1.4 1 0 0 1 1 1 1 Osmosensory transporter coiled coil LCD1 PF09798.4 ETO22396.1 - 0.044 11.7 2.1 0.077 10.9 1.5 1.3 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF3391 PF11871.3 ETO22396.1 - 0.074 13.2 0.1 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) STN1_2 PF09170.5 ETO22397.1 - 0.005 16.6 1.0 0.0055 16.5 0.7 1.2 1 0 0 1 1 1 1 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Vfa1 PF08432.5 ETO22397.1 - 0.58 10.1 13.5 0.74 9.8 9.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF106 PF01956.11 ETO22397.1 - 1.1 8.7 4.4 1.9 7.9 3.1 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF2058 PF09831.4 ETO22397.1 - 3 7.6 13.2 4.4 7.1 9.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Agenet PF05641.7 ETO22399.1 - 0.00028 20.9 0.0 0.00051 20.1 0.0 1.5 1 0 0 1 1 1 1 Agenet domain Ub-RnfH PF03658.9 ETO22399.1 - 0.11 12.4 0.1 0.22 11.3 0.0 1.5 2 0 0 2 2 2 0 RnfH family Ubiquitin zf-C3HC4_3 PF13920.1 ETO22400.1 - 1.8e-08 33.9 10.4 2.8e-08 33.2 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SAM_2 PF07647.12 ETO22400.1 - 2.2e-05 24.2 0.2 4.8e-05 23.1 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-C3HC4_2 PF13923.1 ETO22400.1 - 8.2e-05 22.5 8.8 0.00019 21.3 6.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SAM_1 PF00536.25 ETO22400.1 - 0.00019 21.5 0.0 0.00054 20.0 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Big_3_3 PF13750.1 ETO22400.1 - 0.17 11.3 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) zf-RING_5 PF14634.1 ETO22400.1 - 0.47 10.2 10.3 0.93 9.2 7.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain tRNA-synt_1b PF00579.20 ETO22401.1 - 9.3e-58 195.6 0.0 1.1e-57 195.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Gag_p10 PF02337.12 ETO22401.1 - 0.17 11.6 1.7 0.7 9.6 1.2 2.0 1 1 0 1 1 1 0 Retroviral GAG p10 protein RrnaAD PF00398.15 ETO22403.1 - 2.4e-53 180.8 0.0 7.9e-52 175.8 0.0 2.1 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 ETO22403.1 - 2e-07 31.0 0.0 3.1e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO22403.1 - 2.4e-05 24.8 0.0 4.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO22403.1 - 0.0025 17.4 0.0 0.005 16.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO22403.1 - 0.0032 17.9 0.0 0.0085 16.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 ETO22403.1 - 0.0082 15.2 0.1 0.015 14.3 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 ETO22403.1 - 0.0084 15.8 0.0 0.021 14.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETO22403.1 - 0.0094 16.4 0.0 0.027 14.9 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain DREV PF05219.7 ETO22403.1 - 0.016 14.1 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase MTS PF05175.9 ETO22403.1 - 0.023 14.0 0.0 0.051 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.14 ETO22403.1 - 0.032 13.7 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.8 ETO22403.1 - 0.032 13.5 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_25 PF13649.1 ETO22403.1 - 0.046 14.0 0.0 0.084 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MSC PF09402.5 ETO22403.1 - 0.053 12.2 0.9 0.084 11.5 0.6 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain NodS PF05401.6 ETO22403.1 - 0.08 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_PK PF05891.7 ETO22403.1 - 0.12 11.6 0.2 0.27 10.5 0.1 1.5 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase NAM-associated PF14303.1 ETO22404.1 - 0.081 13.2 10.0 0.17 12.2 6.9 1.5 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Agenet PF05641.7 ETO22404.1 - 0.11 12.6 2.4 0.72 10.0 0.0 2.8 2 1 1 3 3 3 0 Agenet domain WD40 PF00400.27 ETO22405.1 - 0.0003 20.5 6.2 0.0077 16.0 0.3 2.8 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF1673 PF07895.6 ETO22405.1 - 0.013 15.0 6.7 0.019 14.4 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Polysacc_synt PF01943.12 ETO22405.1 - 0.055 12.7 6.6 0.077 12.2 4.6 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein WD40 PF00400.27 ETO22410.1 - 4.3e-46 153.2 3.8 2.6e-12 46.0 0.1 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO22410.1 - 7.9e-09 34.1 0.3 0.074 11.1 0.0 4.0 1 1 3 4 4 4 4 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO22410.1 - 0.0025 17.7 0.2 0.078 12.9 0.0 3.3 3 1 1 4 4 4 2 Domain of unknown function (DUF3601) YHYH PF14240.1 ETO22410.1 - 0.069 12.8 1.0 0.43 10.2 0.1 2.2 1 1 0 2 2 2 0 YHYH protein Bet_v_1 PF00407.14 ETO22410.1 - 0.1 12.2 2.0 0.74 9.4 0.0 2.8 3 1 0 3 3 3 0 Pathogenesis-related protein Bet v I family Methyltransf_25 PF13649.1 ETO22410.1 - 0.15 12.4 0.0 0.44 10.9 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Ctr PF04145.10 ETO22413.1 - 0.14 12.1 1.8 0.51 10.3 1.2 1.9 1 1 0 1 1 1 0 Ctr copper transporter family TcdA_TcdB PF12919.2 ETO22414.1 - 0.0092 14.5 0.9 0.028 12.9 0.2 1.7 1 1 1 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain DUF4551 PF15087.1 ETO22414.1 - 0.47 8.7 7.5 0.47 8.7 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Presenilin PF01080.12 ETO22414.1 - 1 8.0 6.0 1.1 8.0 4.1 1.1 1 0 0 1 1 1 0 Presenilin Rot1 PF10681.4 ETO22414.1 - 1.9 7.7 4.8 2 7.7 2.5 1.6 1 1 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal Nop14 PF04147.7 ETO22416.1 - 7.9 4.2 62.3 22 2.7 43.2 1.8 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 ETO22416.1 - 8.9 4.6 57.7 3 6.2 38.0 1.6 1 1 0 1 1 1 0 Daxx Family DEP PF00610.16 ETO22417.1 - 5.8e-22 77.2 0.6 3.5e-11 42.6 0.0 3.2 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) EF-hand_7 PF13499.1 ETO22417.1 - 3.4e-10 39.9 4.0 6.8e-06 26.1 0.5 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO22417.1 - 2.3e-08 33.2 8.3 0.11 12.4 0.0 5.0 5 0 0 5 5 5 3 EF-hand domain EF-hand_1 PF00036.27 ETO22417.1 - 2.5e-07 29.4 5.3 0.092 12.0 0.1 4.4 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 ETO22417.1 - 0.00025 20.6 3.3 0.00063 19.3 0.1 2.7 2 1 0 2 2 2 1 EF-hand domain pair RXT2_N PF08595.6 ETO22418.1 - 0.0078 16.0 14.0 0.0078 16.0 9.7 2.7 3 0 0 3 3 3 1 RXT2-like, N-terminal Dynein_heavy PF03028.10 ETO22419.1 - 7.2e-30 103.6 0.3 8.5e-30 103.4 0.2 1.0 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor Myotub-related PF06602.9 ETO22420.1 - 5.1e-30 104.4 0.1 6.3e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain RNase_H2-Ydr279 PF09468.5 ETO22421.1 - 0.0097 15.1 4.4 0.0097 15.1 3.1 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Cnd1_N PF12922.2 ETO22421.1 - 0.14 11.7 1.9 0.15 11.6 1.3 1.1 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term YqfQ PF14181.1 ETO22421.1 - 0.2 11.6 3.9 0.18 11.8 2.7 1.1 1 0 0 1 1 1 0 YqfQ-like protein RNA_pol_Rpc4 PF05132.9 ETO22421.1 - 0.29 11.1 3.2 0.27 11.2 2.2 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Med19 PF10278.4 ETO22421.1 - 0.34 10.5 16.2 0.31 10.7 11.2 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Protocadherin PF08374.6 ETO22421.1 - 0.42 10.2 7.4 0.38 10.3 5.2 1.1 1 0 0 1 1 1 0 Protocadherin SspB PF04386.8 ETO22421.1 - 0.42 10.2 4.9 0.44 10.1 3.4 1.1 1 0 0 1 1 1 0 Stringent starvation protein B YL1 PF05764.8 ETO22421.1 - 0.48 9.9 15.5 0.63 9.6 10.8 1.2 1 0 0 1 1 1 0 YL1 nuclear protein HSP90 PF00183.13 ETO22421.1 - 0.78 8.0 13.5 0.8 8.0 9.4 1.0 1 0 0 1 1 1 0 Hsp90 protein CDC45 PF02724.9 ETO22421.1 - 0.8 7.6 9.5 0.81 7.6 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein BCIP PF13862.1 ETO22421.1 - 1.1 8.6 5.9 1.2 8.5 4.1 1.2 1 0 0 1 1 1 0 p21-C-terminal region-binding protein AP-5_subunit_s1 PF15001.1 ETO22421.1 - 1.3 8.9 5.9 1.4 8.8 4.1 1.1 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 ERK-JNK_inhib PF15002.1 ETO22421.1 - 1.8 7.8 15.5 2.1 7.6 10.7 1.1 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor RRP14 PF15459.1 ETO22421.1 - 2 8.5 21.5 4.2 7.5 14.9 1.5 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 Nop14 PF04147.7 ETO22421.1 - 2.6 5.8 13.5 3 5.6 9.4 1.0 1 0 0 1 1 1 0 Nop14-like family Poxvirus_B22R PF04395.7 ETO22421.1 - 2.8 7.3 9.2 3.2 7.2 6.4 1.1 1 0 0 1 1 1 0 Poxvirus B22R protein SPT6_acidic PF14632.1 ETO22421.1 - 3.6 7.8 27.3 10 6.3 18.9 1.7 1 1 0 1 1 1 0 Acidic N-terminal SPT6 DUF788 PF05620.6 ETO22421.1 - 3.9 7.3 6.9 4.6 7.0 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF788) MRC1 PF09444.5 ETO22421.1 - 5 7.4 15.9 0.082 13.2 5.4 1.9 2 0 0 2 2 2 0 MRC1-like domain Sporozoite_P67 PF05642.6 ETO22421.1 - 6.1 4.5 8.7 6.8 4.4 6.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BLVR PF06375.6 ETO22421.1 - 6.8 6.5 22.5 0.16 11.7 11.1 1.5 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) SR-25 PF10500.4 ETO22421.1 - 7.3 5.9 18.0 8.7 5.7 12.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Conotoxin PF02950.12 ETO22421.1 - 8.5 7.2 6.0 12 6.7 4.2 1.3 1 0 0 1 1 1 0 Conotoxin Pkinase PF00069.20 ETO22422.1 - 6.4e-18 64.8 11.0 5.2e-09 35.6 0.5 3.5 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 ETO22422.1 - 0.00016 20.8 7.7 0.013 14.6 5.2 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Adaptin_binding PF10199.4 ETO22422.1 - 0.65 10.2 17.4 0.13 12.5 9.4 1.7 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 DHC_N2 PF08393.8 ETO22423.1 - 1.2e-117 392.8 20.1 1.2e-117 392.8 13.9 3.6 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 ETO22423.1 - 1.6e-101 338.7 0.3 2.4e-100 334.8 0.0 2.8 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 ETO22423.1 - 9.2e-69 231.3 0.0 2e-68 230.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 ETO22423.1 - 4.1e-61 205.7 1.5 4.1e-61 205.7 1.0 2.1 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 MT PF12777.2 ETO22423.1 - 8.5e-47 159.5 19.6 1.8e-46 158.4 13.6 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 ETO22423.1 - 1.3e-46 158.9 0.9 3.2e-45 154.3 0.6 2.6 1 1 0 1 1 1 1 P-loop containing dynein motor region D3 Dynein_heavy PF03028.10 ETO22423.1 - 4e-30 104.5 0.0 4e-30 104.5 0.0 3.3 4 0 0 4 4 3 1 Dynein heavy chain and region D6 of dynein motor AAA_5 PF07728.9 ETO22423.1 - 4.6e-17 62.0 0.5 0.0013 18.4 0.0 6.3 6 1 0 6 6 6 3 AAA domain (dynein-related subfamily) AAA PF00004.24 ETO22423.1 - 5.2e-12 46.1 0.1 0.001 19.2 0.0 4.6 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETO22423.1 - 1.7e-09 37.9 3.5 0.0095 15.9 0.0 6.3 6 1 1 7 7 7 2 AAA ATPase domain AAA_22 PF13401.1 ETO22423.1 - 7.9e-07 29.2 0.7 0.3 11.2 0.0 5.5 5 0 0 5 5 5 2 AAA domain RNA_helicase PF00910.17 ETO22423.1 - 7.9e-05 22.7 0.0 0.9 9.7 0.0 4.0 3 0 0 3 3 3 1 RNA helicase AAA_33 PF13671.1 ETO22423.1 - 0.00018 21.4 0.0 0.72 9.7 0.0 4.3 4 0 0 4 4 4 1 AAA domain NACHT PF05729.7 ETO22423.1 - 0.00028 20.5 0.0 0.18 11.4 0.0 3.7 3 0 0 3 3 3 1 NACHT domain Sigma54_activat PF00158.21 ETO22423.1 - 0.00047 19.6 0.1 0.26 10.7 0.0 3.2 3 0 0 3 3 3 1 Sigma-54 interaction domain UPF0079 PF02367.12 ETO22423.1 - 0.0005 19.6 0.0 8.5 6.0 0.0 3.8 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 ETO22423.1 - 0.00054 20.2 3.7 6.9 7.0 0.0 6.0 5 0 0 5 5 5 0 AAA domain AAA_17 PF13207.1 ETO22423.1 - 0.0011 19.8 8.1 0.22 12.3 0.0 6.7 8 0 0 8 8 4 1 AAA domain Peptidase_MA_2 PF13485.1 ETO22423.1 - 0.0011 19.0 0.1 0.0027 17.7 0.1 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily AAA_19 PF13245.1 ETO22423.1 - 0.031 14.0 0.0 18 5.1 0.0 3.3 3 0 0 3 3 3 0 Part of AAA domain AAA_28 PF13521.1 ETO22423.1 - 0.057 13.3 0.1 8.1 6.3 0.0 4.1 4 0 0 4 4 3 0 AAA domain AAA_29 PF13555.1 ETO22423.1 - 0.12 11.8 0.0 3.3 7.3 0.0 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Dynein_heavy PF03028.10 ETO22424.1 - 7.7e-96 321.7 0.2 9.3e-96 321.4 0.2 1.0 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor Pkinase PF00069.20 ETO22425.1 - 4.5e-07 29.2 0.9 1.5e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO22425.1 - 1.9e-05 23.8 0.0 3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SPX PF03105.14 ETO22425.1 - 0.0026 17.6 15.0 0.0042 16.9 10.4 1.2 1 1 0 1 1 1 1 SPX domain Hid1 PF12722.2 ETO22425.1 - 0.02 12.5 7.6 0.023 12.4 5.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein HAUS2 PF15003.1 ETO22425.1 - 0.74 8.8 6.1 1.1 8.2 4.2 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 RP-C_C PF11800.3 ETO22425.1 - 1.8 8.2 6.0 2.6 7.7 4.2 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region NOA36 PF06524.7 ETO22425.1 - 2 7.5 11.8 2.8 7.1 8.2 1.2 1 0 0 1 1 1 0 NOA36 protein Daxx PF03344.10 ETO22425.1 - 2.7 6.3 14.8 3.2 6.1 10.3 1.1 1 0 0 1 1 1 0 Daxx Family DUF2939 PF11159.3 ETO22426.1 - 0.059 13.5 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) SPX PF03105.14 ETO22426.1 - 0.32 10.7 27.9 2.1 8.0 19.4 2.0 1 1 0 1 1 1 0 SPX domain LMBR1 PF04791.11 ETO22426.1 - 2.3 6.7 7.0 2.7 6.4 4.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FAM60A PF15396.1 ETO22426.1 - 3.9 7.1 9.3 6.5 6.4 6.4 1.4 1 0 0 1 1 1 0 Protein Family FAM60A Neur_chan_memb PF02932.11 ETO22426.1 - 6.7 6.5 6.1 10 5.9 4.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region IFT57 PF10498.4 ETO22427.1 - 0.99 8.0 16.8 0.042 12.6 7.2 1.7 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 CASP_C PF08172.7 ETO22428.1 - 0.0007 18.7 5.8 0.00089 18.3 4.0 1.1 1 0 0 1 1 1 1 CASP C terminal AKNA PF12443.3 ETO22428.1 - 0.0014 18.5 1.8 0.0014 18.5 1.3 1.9 1 1 1 2 2 2 1 AT-hook-containing transcription factor bZIP_1 PF00170.16 ETO22428.1 - 0.005 16.7 1.6 0.005 16.7 1.1 2.0 3 0 0 3 3 2 1 bZIP transcription factor IncA PF04156.9 ETO22428.1 - 0.0052 16.4 9.4 0.0068 16.0 6.5 1.2 1 0 0 1 1 1 1 IncA protein Herpes_BLRF2 PF05812.7 ETO22428.1 - 0.0059 16.4 2.9 0.01 15.6 2.0 1.6 1 1 0 1 1 1 1 Herpesvirus BLRF2 protein DivIC PF04977.10 ETO22428.1 - 0.0059 16.0 3.7 0.0059 16.0 2.5 2.2 1 1 1 2 2 2 1 Septum formation initiator DUF972 PF06156.8 ETO22428.1 - 0.01 16.1 6.0 0.013 15.8 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) RasGAP_C PF03836.10 ETO22428.1 - 0.012 15.3 7.5 0.016 14.8 5.1 1.3 1 1 0 1 1 1 0 RasGAP C-terminus Med9 PF07544.8 ETO22428.1 - 0.015 14.9 2.7 0.015 14.9 1.9 2.6 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Ead_Ea22 PF13935.1 ETO22428.1 - 0.019 15.3 1.4 0.022 15.0 1.0 1.2 1 0 0 1 1 1 0 Ead/Ea22-like protein Nnf1 PF03980.9 ETO22428.1 - 0.019 14.9 3.9 0.037 14.0 2.7 1.6 1 1 0 1 1 1 0 Nnf1 TMF_DNA_bd PF12329.3 ETO22428.1 - 0.02 14.7 17.9 0.021 14.6 7.6 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Viral_P18 PF04521.8 ETO22428.1 - 0.023 14.1 0.5 0.032 13.6 0.4 1.4 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein DUF2216 PF10226.4 ETO22428.1 - 0.024 14.1 2.0 0.029 13.9 1.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved proteins (DUF2216) bZIP_2 PF07716.10 ETO22428.1 - 0.026 14.3 3.4 0.026 14.3 2.4 1.7 2 0 0 2 2 1 0 Basic region leucine zipper Fez1 PF06818.10 ETO22428.1 - 0.026 14.5 5.3 0.029 14.3 3.7 1.0 1 0 0 1 1 1 0 Fez1 Nsp1_C PF05064.8 ETO22428.1 - 0.03 13.9 1.1 0.041 13.5 0.8 1.3 1 0 0 1 1 1 0 Nsp1-like C-terminal region Fib_alpha PF08702.5 ETO22428.1 - 0.032 14.3 3.9 0.029 14.4 2.2 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Striatin PF08232.7 ETO22428.1 - 0.048 13.9 8.9 0.069 13.4 6.2 1.3 1 1 0 1 1 1 0 Striatin family DUF641 PF04859.7 ETO22428.1 - 0.078 12.7 7.9 0.1 12.3 3.6 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF2570 PF10828.3 ETO22428.1 - 0.097 12.2 5.3 0.16 11.6 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) ING PF12998.2 ETO22428.1 - 0.097 12.9 4.1 0.081 13.2 1.7 1.6 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding TSC22 PF01166.13 ETO22428.1 - 0.12 12.3 3.9 0.11 12.4 1.8 1.6 1 1 0 1 1 1 0 TSC-22/dip/bun family DUF1664 PF07889.7 ETO22428.1 - 0.12 12.1 2.9 0.18 11.5 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Herpes_UL6 PF01763.11 ETO22428.1 - 0.23 9.5 3.4 0.24 9.5 2.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF1090 PF06476.7 ETO22428.1 - 0.24 11.0 4.9 0.52 9.9 3.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1090) DUF2051 PF09738.4 ETO22428.1 - 0.25 10.5 10.2 0.51 9.5 7.1 1.5 1 1 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) Atg14 PF10186.4 ETO22428.1 - 0.27 10.1 6.9 0.32 9.9 4.8 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMCO5 PF14992.1 ETO22428.1 - 0.29 10.2 8.6 0.35 9.9 6.0 1.1 1 0 0 1 1 1 0 TMCO5 family SlyX PF04102.7 ETO22428.1 - 0.4 11.0 3.5 0.79 10.1 2.4 1.6 1 1 0 1 1 1 0 SlyX Fmp27_WPPW PF10359.4 ETO22428.1 - 0.43 8.9 8.9 0.47 8.8 6.2 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain CENP-Q PF13094.1 ETO22428.1 - 0.48 10.4 9.4 0.61 10.1 6.5 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DivIVA PF05103.8 ETO22428.1 - 0.57 10.2 6.6 0.64 10.0 3.9 1.6 1 1 0 1 1 1 0 DivIVA protein CENP-F_leu_zip PF10473.4 ETO22428.1 - 0.62 9.9 13.0 0.91 9.3 9.0 1.3 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 ETO22428.1 - 0.69 8.9 7.7 0.73 8.8 5.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Macoilin PF09726.4 ETO22428.1 - 0.87 7.7 8.4 1.2 7.3 5.8 1.3 1 0 0 1 1 1 0 Transmembrane protein Mnd1 PF03962.10 ETO22428.1 - 1.5 8.4 9.6 0.54 9.8 4.3 1.5 1 1 1 2 2 2 0 Mnd1 family RBD-FIP PF09457.5 ETO22428.1 - 1.6 8.5 8.4 0.18 11.5 1.8 2.3 1 1 2 3 3 3 0 FIP domain ADIP PF11559.3 ETO22428.1 - 1.9 8.3 10.7 0.43 10.4 5.0 1.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF904 PF06005.7 ETO22428.1 - 2.5 8.4 11.9 0.48 10.7 5.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF904) V_ATPase_I PF01496.14 ETO22428.1 - 2.9 5.6 6.2 3 5.5 4.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.15 ETO22428.1 - 5.2 6.8 14.1 0.46 10.2 5.7 2.1 2 1 1 3 3 3 0 Prefoldin subunit DUF724 PF05266.9 ETO22428.1 - 5.3 6.6 11.2 7.6 6.1 7.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) FlaC_arch PF05377.6 ETO22428.1 - 7 6.6 7.7 2 8.4 1.4 2.6 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.3 ETO22429.1 - 0.014 15.1 6.5 0.014 15.1 4.5 4.6 4 1 0 4 4 4 0 TATA element modulatory factor 1 DNA binding YfhO PF09586.5 ETO22429.1 - 7.1 4.5 19.4 11 3.8 13.4 1.3 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Herpes_LMP1 PF05297.6 ETO22430.1 - 2 7.2 14.2 2.1 7.2 9.8 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Got1 PF04178.7 ETO22430.1 - 4.2 7.5 16.5 0.12 12.5 4.3 2.2 1 1 1 2 2 2 0 Got1/Sft2-like family Ribosomal_S17 PF00366.15 ETO22431.1 - 0.095 12.7 1.2 0.17 11.9 0.8 1.4 1 0 0 1 1 1 0 Ribosomal protein S17 SAP PF02037.22 ETO22432.1 - 0.0031 16.9 2.5 0.0042 16.5 0.0 2.4 3 0 0 3 3 3 1 SAP domain WD40 PF00400.27 ETO22434.1 - 1.1e-30 104.3 7.5 5e-09 35.7 0.2 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO22434.1 - 9.4e-06 24.0 1.9 0.0088 14.2 0.1 2.9 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Kelch_2 PF07646.10 ETO22434.1 - 0.28 11.0 2.7 9.7 6.1 0.0 2.7 3 0 0 3 3 3 0 Kelch motif IGR PF09597.5 ETO22436.1 - 0.0031 17.3 0.0 0.045 13.6 0.0 2.4 2 0 0 2 2 2 1 IGR protein motif RhoGAP PF00620.22 ETO22437.1 - 3.3e-10 39.7 0.0 5.1e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Invasin_D3 PF09134.5 ETO22437.1 - 0.013 15.3 0.0 0.17 11.7 0.1 2.2 2 0 0 2 2 2 0 Invasin, domain 3 DUF2267 PF10025.4 ETO22437.1 - 0.032 14.3 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) MRP PF09387.5 ETO22437.1 - 0.18 11.5 0.2 0.4 10.3 0.1 1.5 1 1 0 1 1 1 0 Mitochondrial RNA binding protein MRP ELO PF01151.13 ETO22438.1 - 2.4e-28 99.1 5.0 3.2e-28 98.6 3.5 1.3 1 1 0 1 1 1 1 GNS1/SUR4 family WD40 PF00400.27 ETO22440.1 - 6.2e-10 38.5 6.4 2e-06 27.4 0.1 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF155 PF02582.9 ETO22440.1 - 0.09 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 Actin PF00022.14 ETO22441.1 - 7.6e-73 245.1 0.0 8.9e-73 244.9 0.0 1.0 1 0 0 1 1 1 1 Actin DUF1965 PF09248.5 ETO22441.1 - 0.092 12.6 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) Ribosomal_L37ae PF01780.14 ETO22442.1 - 0.01 15.6 0.5 2.6 7.9 0.0 2.9 2 0 0 2 2 2 0 Ribosomal L37ae protein family DUF2531 PF10748.4 ETO22442.1 - 0.2 10.8 4.8 0.087 12.0 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2531) CotJB PF12652.2 ETO22442.1 - 1.2 9.3 0.0 1.2 9.3 0.0 4.0 5 2 2 7 7 7 0 CotJB protein Zip PF02535.17 ETO22442.1 - 9.8 5.0 5.2 8.8 5.2 0.1 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter DUF2201_N PF13203.1 ETO22443.1 - 0.0022 17.2 3.8 0.0028 16.8 2.7 1.1 1 0 0 1 1 1 1 Putative metallopeptidase domain F-box-like PF12937.2 ETO22443.1 - 0.035 13.8 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 F-box-like DUF4463 PF14703.1 ETO22443.1 - 0.49 10.9 13.6 0.36 11.3 7.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) PBP_sp32 PF07222.7 ETO22443.1 - 1.1 8.3 9.5 1.7 7.7 6.6 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Atrophin-1 PF03154.10 ETO22443.1 - 3 5.8 13.3 4.1 5.4 9.2 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF1510 PF07423.6 ETO22443.1 - 3.7 6.8 16.5 6.2 6.1 11.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 ETO22443.1 - 6.2 4.7 15.1 8.3 4.2 10.4 1.1 1 0 0 1 1 1 0 CDC45-like protein AAA_11 PF13086.1 ETO22443.1 - 8.7 5.8 11.3 12 5.3 7.8 1.2 1 0 0 1 1 1 0 AAA domain RGS PF00615.14 ETO22444.1 - 7.1e-10 39.0 0.6 1.2e-09 38.3 0.4 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain GIT_SHD PF08518.6 ETO22445.1 - 6.2 6.2 10.6 3.7 7.0 0.3 3.5 4 0 0 4 4 4 0 Spa2 homology domain (SHD) of GIT MFS_1 PF07690.11 ETO22446.1 - 2.1e-11 43.1 10.1 1.7e-10 40.1 7.0 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily BT1 PF03092.11 ETO22446.1 - 0.0035 16.0 0.1 0.0038 15.9 0.1 1.3 1 0 0 1 1 1 1 BT1 family Calci_bind_CcbP PF11535.3 ETO22446.1 - 0.099 12.9 0.4 0.099 12.9 0.3 1.6 2 0 0 2 2 2 0 Calcium binding Shisa PF13908.1 ETO22446.1 - 0.3 11.2 7.3 0.14 12.3 0.4 2.7 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator SPC25 PF06703.6 ETO22446.1 - 0.47 10.0 2.9 0.76 9.3 0.5 2.4 2 1 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) His_Phos_1 PF00300.17 ETO22447.1 - 8.4e-08 32.4 0.0 4.7e-07 30.0 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF2817 PF10994.3 ETO22449.1 - 1.1e-49 169.4 19.4 6.7e-24 84.5 4.1 4.3 2 1 1 3 3 3 3 Protein of unknown function (DUF2817) Peptidase_M14 PF00246.19 ETO22449.1 - 1.5e-05 24.7 6.6 0.00034 20.3 2.2 2.5 2 1 0 2 2 2 1 Zinc carboxypeptidase AstE_AspA PF04952.9 ETO22449.1 - 0.0096 14.8 0.2 0.021 13.6 0.1 1.5 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family SR-25 PF10500.4 ETO22449.1 - 0.044 13.2 37.9 0.23 10.9 2.9 3.3 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.3 ETO22449.1 - 0.089 12.9 16.0 0.1 12.7 3.8 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Peptidase_S49_N PF08496.5 ETO22449.1 - 0.6 9.8 3.9 1.1 8.9 1.9 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Secretin_N_2 PF07655.8 ETO22449.1 - 2.5 8.5 35.1 0.092 13.1 5.5 3.5 3 0 0 3 3 3 0 Secretin N-terminal domain Pheromone PF08015.6 ETO22449.1 - 2.6 8.9 10.6 13 6.6 1.2 2.9 2 0 0 2 2 2 0 Fungal mating-type pheromone Myco_19_kDa PF05481.7 ETO22449.1 - 5.4 6.8 11.0 0.87 9.3 1.3 2.5 2 0 0 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen DUF912 PF06024.7 ETO22450.1 - 0.0043 17.0 1.2 0.61 10.1 0.2 2.5 2 0 0 2 2 2 2 Nucleopolyhedrovirus protein of unknown function (DUF912) CDC45 PF02724.9 ETO22450.1 - 0.17 9.9 5.9 0.23 9.4 4.1 1.2 1 0 0 1 1 1 0 CDC45-like protein zf-XS PF03470.9 ETO22450.1 - 0.48 10.5 4.5 0.98 9.5 1.8 2.7 2 0 0 2 2 2 0 XS zinc finger domain PBP1_TM PF14812.1 ETO22450.1 - 1.3 9.3 7.1 4.9 7.5 3.8 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tom37_C PF11801.3 ETO22450.1 - 1.6 8.5 8.4 0.45 10.3 3.2 1.8 1 1 1 2 2 2 0 Tom37 C-terminal domain PKI PF02827.11 ETO22450.1 - 2.1 8.5 8.1 18 5.5 3.5 2.3 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor Inhibitor_I71 PF12628.2 ETO22450.1 - 3.4 7.3 10.4 4.2 6.9 2.2 2.6 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor Vma12 PF11712.3 ETO22451.1 - 0.23 11.1 0.1 0.23 11.1 0.0 2.5 3 1 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase SH2 PF00017.19 ETO22453.1 - 1.9e-07 30.7 0.0 8.3e-07 28.7 0.0 2.1 1 1 0 1 1 1 1 SH2 domain Herpes_IE2_3 PF03361.9 ETO22453.1 - 0.0092 15.3 1.4 0.066 12.5 0.0 2.3 2 0 0 2 2 2 1 Herpes virus intermediate/early protein 2/3 T4_deiodinase PF00837.12 ETO22454.1 - 0.15 11.0 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Iodothyronine deiodinase FAM222A PF15258.1 ETO22456.1 - 0.025 13.8 6.1 0.028 13.6 4.3 1.1 1 0 0 1 1 1 0 Protein family of FAM222A SnAPC_2_like PF11035.3 ETO22456.1 - 0.048 13.1 2.6 0.063 12.7 1.8 1.2 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2-like YL1 PF05764.8 ETO22456.1 - 0.063 12.8 23.2 0.097 12.2 16.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Draxin PF15550.1 ETO22456.1 - 0.26 10.9 10.1 0.35 10.4 7.0 1.2 1 0 0 1 1 1 0 Draxin Peptidase_A21 PF03566.8 ETO22456.1 - 0.68 7.9 4.5 0.77 7.7 3.1 1.1 1 0 0 1 1 1 0 Peptidase family A21 DUF4647 PF15504.1 ETO22456.1 - 0.9 8.3 16.0 1.1 8.0 11.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Macoilin PF09726.4 ETO22456.1 - 1.5 7.0 24.7 1.8 6.7 17.1 1.0 1 0 0 1 1 1 0 Transmembrane protein EVI2A PF05399.6 ETO22456.1 - 1.7 7.8 8.7 2.3 7.4 6.0 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) DUF1675 PF07897.6 ETO22456.1 - 3.2 7.5 23.3 4.1 7.2 16.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Lin-8 PF03353.10 ETO22456.1 - 4.2 6.5 19.1 5.6 6.1 13.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF3807 PF12720.2 ETO22456.1 - 4.2 7.4 23.3 6.7 6.8 16.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Med24_N PF11277.3 ETO22456.1 - 5.5 4.3 9.4 6.2 4.1 6.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal DUF572 PF04502.8 ETO22456.1 - 5.5 6.1 25.6 7.9 5.5 17.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4401 PF14351.1 ETO22457.1 - 0.017 14.1 1.5 0.021 13.7 1.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) BUD22 PF09073.5 ETO22457.1 - 0.11 11.5 10.4 0.11 11.5 7.2 1.0 1 0 0 1 1 1 0 BUD22 eIF-3c_N PF05470.7 ETO22457.1 - 0.43 8.6 4.2 0.48 8.4 2.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RRN3 PF05327.6 ETO22457.1 - 0.43 8.6 6.6 0.43 8.6 4.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4484 PF14831.1 ETO22457.1 - 3 7.9 11.2 4.3 7.4 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Pox_Ag35 PF03286.9 ETO22457.1 - 4.2 6.8 7.7 4.9 6.6 5.4 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein UBX PF00789.15 ETO22459.1 - 7.6e-08 32.3 0.0 1.7e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 UBX domain DUF4246 PF14033.1 ETO22459.1 - 0.034 12.7 15.5 0.045 12.3 10.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) DUF572 PF04502.8 ETO22459.1 - 0.43 9.7 22.0 0.54 9.4 15.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF1675 PF07897.6 ETO22459.1 - 1.1 9.0 14.3 1.5 8.6 9.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) CDC45 PF02724.9 ETO22459.1 - 1.4 6.8 21.2 1.7 6.5 14.7 1.0 1 0 0 1 1 1 0 CDC45-like protein PLRV_ORF5 PF01690.12 ETO22459.1 - 3.1 6.8 14.1 3.6 6.6 9.8 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Membralin PF09746.4 ETO22459.1 - 3.5 6.5 6.1 4.9 6.1 4.2 1.2 1 0 0 1 1 1 0 Tumour-associated protein Neur_chan_memb PF02932.11 ETO22459.1 - 7.3 6.3 12.3 8.9 6.1 8.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LMBR1 PF04791.11 ETO22459.1 - 8.8 4.7 13.3 9.7 4.6 9.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-C2H2_6 PF13912.1 ETO22460.1 - 0.0012 18.6 3.1 0.0029 17.4 2.2 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 ETO22460.1 - 0.0028 17.9 4.1 0.012 15.9 2.9 2.2 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-met PF12874.2 ETO22460.1 - 0.022 14.9 3.5 0.1 12.8 2.4 2.2 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 ETO22460.1 - 0.079 13.1 4.3 0.19 11.8 3.0 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 ETO22460.1 - 0.11 12.8 1.8 0.43 11.0 1.3 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger Methyltransf_12 PF08242.7 ETO22460.1 - 0.58 10.6 3.5 2.2 8.8 0.2 2.7 2 0 0 2 2 2 0 Methyltransferase domain CTDII PF01556.13 ETO22461.1 - 5.9e-19 67.7 0.3 7.4e-19 67.4 0.2 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain MCP_N PF05581.7 ETO22462.1 - 0.039 14.1 0.2 0.76 9.9 0.1 2.1 1 1 0 1 1 1 0 Vibrio chemotaxis protein N terminus DUF148 PF02520.12 ETO22462.1 - 0.11 12.3 1.3 0.14 11.9 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF148 CALCOCO1 PF07888.6 ETO22462.1 - 0.11 10.7 2.7 0.13 10.5 1.9 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ArfGap PF01412.13 ETO22463.1 - 1.7e-32 111.6 1.5 4.4e-32 110.2 1.1 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF3513 PF12026.3 ETO22463.1 - 3.8 7.0 7.4 0.46 9.9 1.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3513) PH PF00169.24 ETO22464.1 - 4.6e-05 23.5 2.0 0.00018 21.6 1.0 2.2 2 1 0 2 2 2 1 PH domain PH_8 PF15409.1 ETO22464.1 - 0.00014 21.8 0.1 0.00031 20.7 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.1 ETO22464.1 - 0.0002 21.3 0.1 0.00038 20.4 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Mcp5_PH PF12814.2 ETO22464.1 - 0.055 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology PH_11 PF15413.1 ETO22464.1 - 0.11 12.7 3.3 1.9 8.7 0.2 2.9 2 2 1 3 3 3 0 Pleckstrin homology domain SAPS PF04499.10 ETO22466.1 - 0.034 12.8 8.6 0.037 12.6 6.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.7 ETO22466.1 - 0.2 9.5 37.2 0.24 9.2 25.8 1.0 1 0 0 1 1 1 0 Nop14-like family Ycf1 PF05758.7 ETO22466.1 - 0.2 9.3 5.7 0.21 9.2 3.9 1.1 1 0 0 1 1 1 0 Ycf1 Neur_chan_memb PF02932.11 ETO22466.1 - 0.24 11.2 2.3 0.31 10.8 1.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SPX PF03105.14 ETO22466.1 - 0.28 10.9 17.1 0.39 10.4 11.9 1.2 1 0 0 1 1 1 0 SPX domain Daxx PF03344.10 ETO22466.1 - 0.49 8.8 29.6 0.69 8.3 20.5 1.2 1 0 0 1 1 1 0 Daxx Family TFIIF_alpha PF05793.7 ETO22466.1 - 0.55 8.5 32.9 0.69 8.2 22.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Hid1 PF12722.2 ETO22466.1 - 2 5.9 12.7 2.4 5.7 8.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1510 PF07423.6 ETO22466.1 - 3.2 7.0 28.0 4.5 6.5 19.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) BUD22 PF09073.5 ETO22466.1 - 5.3 5.9 28.5 6.6 5.6 19.7 1.1 1 0 0 1 1 1 0 BUD22 Trypan_PARP PF05887.6 ETO22466.1 - 6.4 6.5 10.7 8.9 6.1 7.4 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Nucleotid_trans PF03407.11 ETO22467.1 - 6.3e-22 78.4 0.0 9.5e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF2178 PF09946.4 ETO22467.1 - 0.014 15.1 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DEP PF00610.16 ETO22468.1 - 5.5e-18 64.4 0.1 8.2e-18 63.9 0.1 1.3 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Steroid_dh PF02544.11 ETO22469.1 - 3.1e-50 169.8 3.2 3.1e-50 169.8 2.2 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 ETO22469.1 - 1.1e-06 28.1 0.0 2.2e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 ETO22469.1 - 3.7e-05 23.7 0.1 0.00014 21.9 0.0 2.0 1 0 0 1 1 1 1 Phospholipid methyltransferase ParA PF10609.4 ETO22470.1 - 4.8e-34 116.0 1.1 1e-33 115.0 0.8 1.6 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 ETO22470.1 - 1.3e-18 67.1 0.1 3.4e-18 65.7 0.0 1.7 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 ETO22470.1 - 2.9e-08 33.8 0.1 7.2e-07 29.2 0.0 2.6 3 0 0 3 3 3 1 AAA domain MipZ PF09140.6 ETO22470.1 - 3.8e-08 32.7 1.8 3.8e-07 29.4 0.1 2.7 2 1 0 2 2 2 1 ATPase MipZ DUF971 PF06155.7 ETO22470.1 - 3.2e-05 24.2 0.0 0.00012 22.4 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF971) ArsA_ATPase PF02374.10 ETO22470.1 - 0.00013 21.1 1.7 0.002 17.2 0.0 2.8 2 1 1 3 3 3 1 Anion-transporting ATPase YhjQ PF06564.7 ETO22470.1 - 0.0054 16.1 0.0 0.054 12.8 0.0 2.0 2 0 0 2 2 2 1 YhjQ protein VirC1 PF07015.6 ETO22470.1 - 0.012 14.6 0.0 0.025 13.6 0.0 1.5 1 0 0 1 1 1 0 VirC1 protein Fer4_NifH PF00142.13 ETO22470.1 - 0.014 14.6 0.0 0.037 13.2 0.0 1.7 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF2442 PF10387.4 ETO22470.1 - 0.061 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2442) Pkinase PF00069.20 ETO22471.1 - 1.5e-52 178.3 0.2 8.6e-52 175.8 0.2 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO22471.1 - 1.6e-22 79.8 0.1 3.1e-13 49.4 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase EF-hand_7 PF13499.1 ETO22471.1 - 3.2e-11 43.1 3.9 9.4e-06 25.6 0.3 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 ETO22471.1 - 2.7e-08 32.5 7.7 2.1e-06 26.5 0.5 2.9 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 ETO22471.1 - 2.4e-07 30.2 4.7 1.9e-06 27.4 0.3 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO22471.1 - 2.8e-05 23.6 6.3 0.075 12.9 0.2 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 ETO22471.1 - 0.00011 21.3 7.1 0.00042 19.5 0.5 2.7 2 0 0 2 2 2 1 EF hand YrbL-PhoP_reg PF10707.4 ETO22471.1 - 0.00024 20.5 0.0 0.0006 19.1 0.0 1.6 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 ETO22471.1 - 0.00062 18.8 0.2 0.0022 17.0 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_4 PF12763.2 ETO22471.1 - 0.0017 18.0 2.4 0.039 13.7 0.0 3.2 3 0 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand APH PF01636.18 ETO22471.1 - 0.002 17.8 0.9 0.0042 16.8 0.0 1.9 3 0 0 3 3 3 1 Phosphotransferase enzyme family Unstab_antitox PF09720.5 ETO22471.1 - 0.23 11.1 1.9 0.3 10.8 0.1 2.1 2 0 0 2 2 2 0 Putative addiction module component Daxx PF03344.10 ETO22472.1 - 0.014 13.9 16.8 0.017 13.6 11.6 1.2 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 ETO22472.1 - 0.87 7.5 14.4 1.4 6.8 10.0 1.4 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 ETO22472.1 - 1.4 8.1 18.5 0.076 12.2 9.1 1.6 2 0 0 2 2 2 0 NOA36 protein Nucleoplasmin PF03066.10 ETO22472.1 - 4.1 6.9 11.3 5.6 6.4 5.5 2.4 2 0 0 2 2 2 0 Nucleoplasmin Aa_trans PF01490.13 ETO22473.1 - 8.4e-18 64.0 0.0 1.1e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 ETO22473.1 - 0.013 14.0 0.3 0.048 12.1 0.1 1.9 2 0 0 2 2 2 0 Amino acid permease Aa_trans PF01490.13 ETO22474.1 - 4.6e-21 74.7 11.4 5.8e-21 74.4 7.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4576 PF15144.1 ETO22474.1 - 0.26 10.9 1.7 5.6 6.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4576) Cytochrom_B_C PF00032.12 ETO22474.1 - 1.1 9.4 4.2 1.5 9.0 0.1 2.6 3 0 0 3 3 3 0 Cytochrome b(C-terminal)/b6/petD RNase_H2-Ydr279 PF09468.5 ETO22475.1 - 0.0024 17.1 2.5 0.0038 16.4 1.7 1.3 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Sec62 PF03839.11 ETO22475.1 - 0.0032 16.9 1.7 0.0062 15.9 1.2 1.5 1 0 0 1 1 1 1 Translocation protein Sec62 Neur_chan_memb PF02932.11 ETO22475.1 - 0.1 12.5 2.3 0.089 12.6 0.2 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Tim54 PF11711.3 ETO22475.1 - 6 5.3 10.6 9.5 4.6 7.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 AAA_23 PF13476.1 ETO22476.1 - 0.0018 18.6 5.4 0.0026 18.1 3.8 1.2 1 0 0 1 1 1 1 AAA domain DUF1395 PF07160.7 ETO22476.1 - 0.0065 15.9 2.0 0.13 11.7 0.1 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1395) cNMP_binding PF00027.24 ETO22476.1 - 0.034 13.9 0.0 0.066 13.0 0.0 1.5 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain eIF3_p135 PF12807.2 ETO22476.1 - 0.034 14.0 3.1 0.61 10.0 0.1 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit 135 FtsK_SpoIIIE PF01580.13 ETO22476.1 - 0.059 12.8 0.0 0.084 12.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Phe_tRNA-synt_N PF02912.13 ETO22476.1 - 0.14 11.9 4.9 0.35 10.6 3.4 1.8 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain Syntaxin PF00804.20 ETO22476.1 - 0.6 10.2 6.9 1 9.5 4.4 1.7 1 1 0 1 1 1 0 Syntaxin Pkinase PF00069.20 ETO22478.1 - 6.7e-07 28.7 0.0 9.2e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO22478.1 - 0.055 12.5 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase FAM110_C PF14160.1 ETO22479.1 - 2 9.3 4.5 26 5.7 0.1 2.2 2 0 0 2 2 2 0 Centrosome-associated C terminus PP1c_bdg PF10488.4 ETO22479.1 - 2.4 7.2 18.3 3 6.9 12.7 1.0 1 0 0 1 1 1 0 Phosphatase-1 catalytic subunit binding region MIP-T3 PF10243.4 ETO22480.1 - 8.2 4.7 46.4 10 4.4 32.1 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 GPAT_N PF14829.1 ETO22481.1 - 0.044 13.4 0.9 0.083 12.5 0.5 1.6 1 1 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal DUF2229 PF09989.4 ETO22481.1 - 0.059 12.8 3.4 0.063 12.7 2.3 1.1 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) zf-CCHC_5 PF14787.1 ETO22481.1 - 5.4 6.5 7.8 0.47 9.9 1.8 1.9 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Vps16_N PF04841.8 ETO22482.1 - 2.9e-08 32.6 0.1 3.7e-08 32.3 0.1 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Imm46 PF15585.1 ETO22482.1 - 0.024 14.6 0.4 0.14 12.1 0.1 2.1 2 1 0 2 2 2 0 Immunity protein 46 WbqC PF08889.6 ETO22482.1 - 0.1 12.0 0.1 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 WbqC-like protein family Chlam_PMP PF02415.12 ETO22483.1 - 3.4e-05 23.8 38.8 0.093 13.0 0.4 9.6 10 0 0 10 10 10 6 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Radical_SAM PF04055.16 ETO22485.1 - 4.3e-07 30.2 0.1 3.3e-06 27.3 0.0 2.2 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 ETO22485.1 - 3.8e-05 23.6 0.7 0.00012 22.0 0.5 1.8 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 ETO22485.1 - 0.0022 18.1 0.5 0.0052 16.9 0.3 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF1357 PF07094.6 ETO22485.1 - 0.054 12.9 1.2 0.091 12.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1357) Helicase_C PF00271.26 ETO22486.1 - 5.9e-21 74.1 0.0 1.1e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETO22486.1 - 2e-14 53.4 0.0 5.2e-14 52.0 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2608 PF11019.3 ETO22486.1 - 0.0075 15.2 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2608) zf-RING_2 PF13639.1 ETO22487.1 - 4.3e-07 29.6 1.8 6.3e-07 29.1 1.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO22487.1 - 7.9e-05 22.6 1.6 0.00013 21.9 1.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO22487.1 - 8.2e-05 22.1 1.5 0.00014 21.4 1.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO22487.1 - 0.00019 21.1 1.0 0.00033 20.3 0.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 ETO22487.1 - 0.00049 19.7 1.5 0.00072 19.1 1.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETO22487.1 - 0.0083 16.2 1.9 0.041 13.9 1.3 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger G10 PF01125.12 ETO22487.1 - 0.029 13.9 0.3 0.037 13.5 0.2 1.1 1 0 0 1 1 1 0 G10 protein zf-RING_UBOX PF13445.1 ETO22487.1 - 0.045 13.4 1.9 0.18 11.5 1.3 2.1 1 0 0 1 1 1 0 RING-type zinc-finger zf-HC5HC2H_2 PF13832.1 ETO22487.1 - 0.15 12.0 1.5 0.18 11.7 0.7 1.4 1 1 0 1 1 1 0 PHD-zinc-finger like domain TPR_12 PF13424.1 ETO22488.1 - 1.1e-45 153.4 5.4 3.7e-21 74.8 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO22488.1 - 4.5e-37 125.5 28.2 5.9e-15 54.6 0.5 4.9 2 1 3 5 5 5 4 TPR repeat TPR_1 PF00515.23 ETO22488.1 - 1.7e-30 103.3 27.6 1.3e-08 34.0 0.6 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO22488.1 - 2e-23 80.3 20.7 3.7e-06 26.4 0.1 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO22488.1 - 1.4e-21 75.6 0.2 0.00013 21.8 0.0 4.9 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO22488.1 - 1.3e-20 71.4 8.6 3.8e-05 23.1 0.0 5.4 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO22488.1 - 5e-18 63.4 26.6 5.9e-05 22.5 1.5 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat SNAP PF14938.1 ETO22488.1 - 2.2e-09 36.9 4.2 3.3e-08 33.0 0.2 2.6 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_16 PF13432.1 ETO22488.1 - 3.6e-09 37.0 0.0 0.0022 18.5 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO22488.1 - 2e-08 34.1 0.0 6.1 7.7 0.0 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO22488.1 - 1.1e-06 28.3 5.2 0.11 12.7 0.0 5.3 5 1 2 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO22488.1 - 2.4e-06 27.6 1.5 2.2 8.9 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO22488.1 - 3e-06 26.3 5.2 0.25 10.6 0.0 4.7 5 0 0 5 5 5 2 SHNi-TPR Apc3 PF12895.2 ETO22488.1 - 1.6e-05 24.9 12.9 0.00075 19.5 3.2 3.8 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 ETO22488.1 - 0.00025 20.8 13.6 0.63 9.9 0.5 5.7 5 0 0 5 5 5 1 MIT (microtubule interacting and transport) domain TPR_19 PF14559.1 ETO22488.1 - 0.0039 17.5 0.0 3.1 8.2 0.0 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat POTRA_1 PF08478.5 ETO22488.1 - 0.005 16.8 0.1 0.017 15.1 0.1 1.9 1 0 0 1 1 1 1 POTRA domain, FtsQ-type TPR_3 PF07720.7 ETO22488.1 - 0.016 14.9 7.1 3.5 7.5 0.3 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.4 ETO22488.1 - 0.036 13.4 6.0 4.7 6.5 0.0 3.8 3 1 1 4 4 4 0 26S proteasome subunit RPN7 TPR_9 PF13371.1 ETO22488.1 - 0.099 12.5 0.1 1.7 8.5 0.0 2.8 2 1 0 3 3 2 0 Tetratricopeptide repeat PPR PF01535.15 ETO22488.1 - 4.3 7.5 9.3 21 5.3 0.0 5.0 6 0 0 6 6 5 0 PPR repeat WD40 PF00400.27 ETO22489.1 - 2.2e-42 141.4 10.2 4.3e-11 42.2 0.1 7.1 7 1 0 7 7 7 5 WD domain, G-beta repeat PD40 PF07676.7 ETO22489.1 - 0.00031 20.3 4.9 17 5.2 0.1 5.0 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 ETO22489.1 - 0.00043 19.4 1.9 0.012 14.7 0.1 3.4 2 2 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal DUF4221 PF13970.1 ETO22489.1 - 0.027 13.7 0.8 2.6 7.2 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4221) Str_synth PF03088.11 ETO22489.1 - 0.066 13.2 0.5 27 4.9 0.0 4.5 3 2 3 6 6 6 0 Strictosidine synthase Zip PF02535.17 ETO22490.1 - 0.43 9.5 1.5 0.45 9.4 1.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Ribosomal_60s PF00428.14 ETO22491.1 - 5.8e-05 23.4 16.5 0.0016 18.8 11.4 2.5 1 1 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_L10 PF00466.15 ETO22492.1 - 2.9e-11 43.1 0.1 5.7e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 TPR_12 PF13424.1 ETO22494.1 - 2.6e-32 110.5 5.8 4.2e-21 74.6 1.6 3.7 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO22494.1 - 6.3e-22 77.0 11.1 1.9e-13 49.8 2.6 2.9 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETO22494.1 - 1.7e-14 52.6 20.9 6.7e-09 34.9 0.3 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO22494.1 - 3.4e-14 51.5 9.8 4e-07 29.4 0.1 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO22494.1 - 2.4e-13 49.5 0.0 6.8e-06 25.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO22494.1 - 5.6e-13 47.6 3.3 7.4e-06 25.3 0.0 3.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO22494.1 - 2.3e-11 42.5 21.4 5.3e-06 25.8 0.6 4.9 4 1 0 4 4 4 2 Tetratricopeptide repeat MIT PF04212.13 ETO22494.1 - 3.2e-09 36.5 4.6 0.00091 19.0 0.1 2.8 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain TPR_17 PF13431.1 ETO22494.1 - 1.1e-05 25.1 6.3 0.019 15.1 0.1 3.3 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO22494.1 - 0.00018 21.7 1.1 0.25 11.8 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF2225 PF09986.4 ETO22494.1 - 0.0089 15.5 5.7 0.023 14.1 3.9 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_14 PF13428.1 ETO22494.1 - 0.012 16.2 0.0 9.4 7.1 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.7 ETO22494.1 - 0.022 14.5 4.4 0.83 9.5 0.7 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETO22494.1 - 0.022 15.4 0.0 0.19 12.4 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 ETO22494.1 - 0.023 14.8 5.6 0.052 13.6 2.9 2.4 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 NSF PF02071.15 ETO22494.1 - 4 8.4 10.1 12 6.9 0.4 4.5 4 0 0 4 4 3 0 Aromatic-di-Alanine (AdAR) repeat Ubiq-assoc PF09145.5 ETO22494.1 - 7.1 6.5 6.8 6.9 6.6 0.1 3.5 4 0 0 4 4 3 0 Ubiquitin-associated Peptidase_C12 PF01088.16 ETO22495.1 - 0.051 12.7 0.2 0.11 11.6 0.0 1.6 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase, family 1 Pkinase PF00069.20 ETO22496.1 - 0.00038 19.7 0.0 0.00044 19.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DEP PF00610.16 ETO22498.1 - 1.3e-10 40.8 0.9 1.4e-09 37.5 0.1 2.4 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DASH_Dad3 PF08656.5 ETO22498.1 - 0.015 14.9 1.7 0.037 13.7 0.1 2.4 3 0 0 3 3 3 0 DASH complex subunit Dad3 DUF2371 PF10177.4 ETO22499.1 - 0.072 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) TarH PF02203.10 ETO22500.1 - 0.08 12.7 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Tar ligand binding domain homologue DUF2407_C PF13373.1 ETO22501.1 - 1.7 8.5 15.0 0.23 11.3 6.1 2.4 1 1 1 2 2 2 0 DUF2407 C-terminal domain DUF2115 PF09888.4 ETO22501.1 - 7 6.7 9.6 15 5.6 6.7 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) BPL_N PF09825.4 ETO22501.1 - 8.1 5.1 10.1 12 4.5 7.0 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Pyr_redox_dim PF02852.17 ETO22502.1 - 3.6e-34 117.1 0.2 1e-33 115.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 ETO22502.1 - 1.1e-21 77.0 0.3 4.7e-21 74.9 0.2 2.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETO22502.1 - 3.1e-19 69.6 5.2 3.3e-17 63.0 2.6 3.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETO22502.1 - 3.2e-09 37.1 1.2 0.00028 21.0 0.0 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETO22502.1 - 1.8e-07 30.3 0.2 0.00074 18.5 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 ETO22502.1 - 4.3e-05 22.7 1.7 0.16 11.0 0.0 3.2 3 1 0 3 3 3 2 FAD binding domain DAO PF01266.19 ETO22502.1 - 7.4e-05 21.8 3.6 1.3 7.8 0.0 3.2 3 0 0 3 3 3 3 FAD dependent oxidoreductase Amino_oxidase PF01593.19 ETO22502.1 - 0.0012 17.9 0.6 0.34 9.9 0.1 2.5 1 1 2 3 3 3 2 Flavin containing amine oxidoreductase HI0933_like PF03486.9 ETO22502.1 - 0.0012 17.3 3.3 0.42 9.0 0.1 3.1 2 1 1 3 3 3 2 HI0933-like protein Mqo PF06039.10 ETO22502.1 - 0.0014 16.8 1.4 0.028 12.5 0.1 2.2 1 1 1 2 2 2 1 Malate:quinone oxidoreductase (Mqo) 3HCDH_N PF02737.13 ETO22502.1 - 0.0024 17.5 0.9 0.016 14.8 0.1 2.5 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 ETO22502.1 - 0.022 14.3 0.0 0.043 13.3 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 ETO22502.1 - 0.6 8.8 4.6 5.1 5.8 0.1 2.8 2 1 1 3 3 3 0 FAD binding domain PARP PF00644.15 ETO22503.1 - 4.4e-08 32.7 0.2 1.7e-07 30.8 0.0 1.7 1 1 1 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain DUF4206 PF13901.1 ETO22504.1 - 3.8e-14 52.7 2.9 1.3e-10 41.1 0.4 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4206) RecR PF02132.10 ETO22504.1 - 0.19 11.2 3.6 2.2 7.7 0.1 2.5 2 0 0 2 2 2 0 RecR protein LIM PF00412.17 ETO22504.1 - 1.1 9.4 15.5 2.5 8.2 3.5 3.7 4 0 0 4 4 4 0 LIM domain CRM1_C PF08767.6 ETO22505.1 - 0.089 11.6 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 CRM1 C terminal MRP-L28 PF09812.4 ETO22505.1 - 0.089 12.6 0.9 0.42 10.4 0.6 1.9 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L28 Mito_carr PF00153.22 ETO22507.1 - 2.4e-53 177.8 0.4 1.6e-18 66.1 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein HIGH_NTase1 PF05636.6 ETO22509.1 - 0.033 13.2 0.2 0.045 12.7 0.1 1.1 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase Flg_hook PF02120.11 ETO22510.1 - 8.9 6.0 12.7 0.6 9.8 0.0 3.2 3 1 0 3 3 3 0 Flagellar hook-length control protein FliK AHS1 PF02682.11 ETO22510.1 - 9.8 5.5 12.4 1.1 8.7 0.2 3.3 3 0 0 3 3 3 0 Allophanate hydrolase subunit 1 MFS_1_like PF12832.2 ETO22512.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 MFS_1 like family DUF3060 PF11259.3 ETO22513.1 - 0.071 12.7 1.2 0.12 11.9 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3060) LRR_4 PF12799.2 ETO22514.1 - 4.9e-19 67.5 43.6 5.4e-09 35.4 3.3 5.5 4 2 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO22514.1 - 2.2e-13 49.7 24.5 9.6e-09 34.8 5.5 2.8 1 1 1 2 2 2 2 Leucine rich repeat LRR_9 PF14580.1 ETO22514.1 - 3e-13 49.7 10.6 1.3e-12 47.5 3.8 2.7 2 1 0 3 3 3 1 Leucine-rich repeat LRR_7 PF13504.1 ETO22514.1 - 0.00015 21.4 20.3 1.4 9.4 0.2 6.8 7 0 0 7 7 7 2 Leucine rich repeat LRR_6 PF13516.1 ETO22514.1 - 0.00044 20.0 30.2 0.027 14.5 0.2 6.7 6 1 1 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.28 ETO22514.1 - 0.0041 16.9 35.4 0.21 11.7 1.6 7.0 7 0 0 7 7 7 3 Leucine Rich Repeat NPV_P10 PF05531.7 ETO22515.1 - 0.029 14.6 0.5 0.029 14.6 0.3 18.8 9 5 8 18 18 18 0 Nucleopolyhedrovirus P10 protein DUF3637 PF12337.3 ETO22515.1 - 0.056 13.4 0.5 2.7 8.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3637) MIP-T3 PF10243.4 ETO22516.1 - 0.0022 16.5 28.1 0.0026 16.3 19.5 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Pox_Ag35 PF03286.9 ETO22516.1 - 0.014 14.9 22.0 0.03 13.8 15.3 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2011 PF09428.5 ETO22516.1 - 0.12 12.2 19.1 0.23 11.3 13.2 1.4 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2011) TPR_11 PF13414.1 ETO22517.1 - 8.3e-28 95.8 18.7 1e-08 34.6 0.9 5.6 3 1 2 5 5 5 5 TPR repeat TPR_2 PF07719.12 ETO22517.1 - 2.9e-25 86.1 14.6 0.0027 17.5 0.0 7.8 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETO22517.1 - 2.7e-22 77.3 20.5 0.00035 20.0 0.0 8.1 8 1 0 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.1 ETO22517.1 - 4.9e-22 77.6 20.7 1.4e-07 31.3 0.9 6.1 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 ETO22517.1 - 1.4e-16 59.4 0.1 0.072 13.7 0.0 6.8 3 1 3 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO22517.1 - 4.4e-16 59.0 4.2 2.8e-05 24.6 0.2 5.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO22517.1 - 4.7e-14 51.0 15.9 0.016 14.9 0.0 7.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 ETO22517.1 - 1.2e-11 43.7 17.2 0.082 13.1 0.1 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 ETO22517.1 - 8e-09 35.7 1.9 0.51 10.7 0.1 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat SAM_2 PF07647.12 ETO22517.1 - 1.7e-08 34.2 0.3 5.3e-08 32.5 0.2 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) TPR_7 PF13176.1 ETO22517.1 - 3.6e-08 32.6 18.6 0.45 10.4 0.1 8.2 8 1 0 8 8 7 3 Tetratricopeptide repeat SAM_1 PF00536.25 ETO22517.1 - 5.9e-08 32.7 0.3 5.9e-08 32.7 0.2 1.8 2 0 0 2 2 1 1 SAM domain (Sterile alpha motif) TPR_6 PF13174.1 ETO22517.1 - 9.4e-05 22.6 9.0 0.016 15.6 0.1 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat MIT PF04212.13 ETO22517.1 - 0.0016 18.2 6.0 10 6.0 0.0 6.0 4 1 2 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 ETO22517.1 - 0.0026 17.6 6.1 17 5.4 0.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat SPX PF03105.14 ETO22517.1 - 0.031 14.0 25.4 0.0047 16.7 12.6 2.6 2 1 0 2 2 2 0 SPX domain IGR PF09597.5 ETO22517.1 - 0.041 13.7 0.1 0.11 12.3 0.1 1.8 1 0 0 1 1 1 0 IGR protein motif Gti1_Pac2 PF09729.4 ETO22517.1 - 0.86 9.4 9.4 2.6 7.8 0.2 3.2 3 0 0 3 3 3 0 Gti1/Pac2 family EMG1 PF03587.9 ETO22518.1 - 1.3e-36 125.8 0.1 1.4e-36 125.7 0.1 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Pkinase PF00069.20 ETO22519.1 - 6.9e-21 74.5 0.1 4.6e-20 71.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Neur_chan_memb PF02932.11 ETO22521.1 - 9.4 6.0 11.3 0.72 9.6 0.2 2.6 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PEX11 PF05648.9 ETO22522.1 - 0.12 11.6 2.8 0.3 10.3 0.1 2.2 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) DEP PF00610.16 ETO22523.1 - 2.2e-16 59.3 0.1 5.4e-16 58.1 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) EF-hand_7 PF13499.1 ETO22523.1 - 1.6e-06 28.1 0.4 9.9e-05 22.4 0.3 3.0 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO22523.1 - 6.3e-06 25.1 1.4 0.0015 17.6 0.1 3.6 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 ETO22523.1 - 0.00048 19.6 0.1 0.098 12.2 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO22523.1 - 0.0013 18.4 1.1 0.084 12.8 0.1 3.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 ETO22523.1 - 0.0034 16.6 0.9 0.022 14.0 0.2 2.4 2 0 0 2 2 2 1 EF hand 7tm_1 PF00001.16 ETO22524.1 - 0.016 14.3 4.6 0.019 14.1 0.6 2.1 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) Vma12 PF11712.3 ETO22524.1 - 0.58 9.8 7.4 0.071 12.8 0.4 2.3 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase ABC2_membrane_2 PF12679.2 ETO22524.1 - 8.6 5.1 10.9 14 4.3 5.6 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein Choline_transpo PF04515.7 ETO22525.1 - 3.7e-39 134.3 11.9 4.2e-39 134.2 8.2 1.0 1 0 0 1 1 1 1 Plasma-membrane choline transporter DUF4190 PF13828.1 ETO22525.1 - 1 8.9 11.7 1.3 8.6 1.6 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4190) Metallophos PF00149.23 ETO22526.1 - 0.0015 17.9 1.8 0.0096 15.3 1.2 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase PF00069.20 ETO22527.1 - 0.0013 17.9 0.4 0.0038 16.4 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain DUF4407 PF14362.1 ETO22527.1 - 0.015 14.3 0.5 0.021 13.7 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SprA-related PF12118.3 ETO22527.1 - 0.038 13.3 19.8 0.052 12.8 13.7 1.2 1 0 0 1 1 1 0 SprA-related family Ndc1_Nup PF09531.5 ETO22527.1 - 0.22 9.8 3.3 0.28 9.5 2.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Neur_chan_memb PF02932.11 ETO22527.1 - 0.41 10.4 9.7 0.7 9.7 6.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF605 PF04652.11 ETO22527.1 - 0.51 9.6 17.4 0.78 9.0 12.0 1.3 1 0 0 1 1 1 0 Vta1 like Hid1 PF12722.2 ETO22527.1 - 0.95 7.0 19.0 1.3 6.6 13.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RED_N PF07808.8 ETO22527.1 - 1.8 7.6 23.1 0.27 10.4 12.8 1.8 2 0 0 2 2 2 0 RED-like protein N-terminal region DUF2201_N PF13203.1 ETO22527.1 - 2.8 7.0 12.1 3.9 6.5 8.4 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Suf PF05843.9 ETO22527.1 - 3.9 7.1 12.8 1.3 8.6 7.1 1.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) BPL_N PF09825.4 ETO22527.1 - 8 5.1 9.9 65 2.1 5.5 2.0 1 1 1 2 2 2 0 Biotin-protein ligase, N terminal Pkinase PF00069.20 ETO22528.1 - 6.4e-40 136.9 0.0 1.6e-39 135.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO22528.1 - 4.2e-18 65.3 0.0 1.4e-17 63.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 ETO22528.1 - 0.0038 17.7 1.0 0.0062 17.0 0.7 1.4 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.9 ETO22528.1 - 0.0057 15.7 0.1 0.041 12.9 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETO22528.1 - 0.032 13.1 0.0 0.042 12.7 0.0 1.1 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 ETO22528.1 - 0.048 13.3 0.0 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family WD40 PF00400.27 ETO22529.1 - 2.7e-163 524.7 42.9 3.8e-14 51.9 0.2 14.3 14 0 0 14 14 14 14 WD domain, G-beta repeat DUF3312 PF11768.3 ETO22529.1 - 1.4e-05 23.5 0.5 0.22 9.6 0.0 5.3 3 2 5 8 8 8 1 Protein of unknown function (DUF3312) DUF727 PF05303.7 ETO22529.1 - 3.8e-05 23.4 5.4 6 6.6 0.0 8.2 7 1 3 10 10 10 1 Protein of unknown function (DUF727) PD40 PF07676.7 ETO22529.1 - 3.9e-05 23.2 27.4 17 5.2 0.3 10.2 10 0 0 10 10 10 1 WD40-like Beta Propeller Repeat Pentapeptide_4 PF13599.1 ETO22529.1 - 0.00028 20.6 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 ETO22529.1 - 0.0005 19.9 0.7 0.0086 15.9 0.0 3.2 2 1 1 3 3 3 2 Pentapeptide repeats (9 copies) Cytochrom_D1 PF02239.11 ETO22529.1 - 0.00055 18.3 4.3 0.35 9.1 0.0 4.5 2 2 1 4 4 4 2 Cytochrome D1 heme domain Pentapeptide PF00805.17 ETO22529.1 - 0.0051 16.0 0.1 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) DUF4367 PF14285.1 ETO22530.1 - 0.011 15.0 0.4 0.016 14.4 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4367) RelA_SpoT PF04607.12 ETO22531.1 - 0.0019 18.2 0.6 0.0066 16.4 0.4 1.9 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins TMEM154 PF15102.1 ETO22531.1 - 0.014 15.0 0.2 0.032 13.9 0.2 1.5 1 0 0 1 1 1 0 TMEM154 protein family zf-H2C2_2 PF13465.1 ETO22531.1 - 0.11 12.8 0.1 0.11 12.8 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger double domain Kelch_4 PF13418.1 ETO22533.1 - 2.9e-18 65.3 0.0 0.00022 20.8 0.0 4.3 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO22533.1 - 9e-15 54.3 5.2 4.2e-10 39.5 0.0 4.9 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO22533.1 - 8.4e-14 51.1 0.1 0.0018 18.1 0.0 4.4 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 ETO22533.1 - 3e-09 36.6 0.0 0.26 11.5 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 ETO22533.1 - 2e-05 24.0 0.0 0.031 13.8 0.0 3.6 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO22533.1 - 4.6e-05 23.0 0.1 0.035 13.8 0.1 3.5 3 0 0 3 3 3 1 Kelch motif DUF3752 PF12572.3 ETO22534.1 - 0.005 16.9 1.2 0.0086 16.2 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) LSM PF01423.17 ETO22534.1 - 0.084 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 LSM domain Peptidase_C14 PF00656.17 ETO22535.1 - 1.2e-11 44.7 1.3 2.7e-11 43.6 0.9 1.6 1 0 0 1 1 1 1 Caspase domain Kelch_1 PF01344.20 ETO22535.1 - 1.6e-06 27.5 14.9 5.8e-06 25.7 0.3 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 ETO22535.1 - 2e-06 27.5 4.6 0.11 12.5 1.1 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO22535.1 - 8.2e-06 25.4 0.4 0.0096 15.6 0.0 3.0 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO22535.1 - 4.8e-05 23.3 13.6 0.001 19.1 0.5 5.4 4 1 1 5 5 5 2 Kelch motif Kelch_3 PF13415.1 ETO22535.1 - 0.0035 17.4 2.1 0.13 12.4 0.0 3.6 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO22535.1 - 0.019 14.6 10.1 0.063 13.0 0.3 5.3 6 0 0 6 6 6 0 Kelch motif SAM_1 PF00536.25 ETO22536.1 - 1.5e-06 28.2 1.0 2.4e-06 27.6 0.7 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 ETO22536.1 - 7.1e-06 25.6 1.9 1.5e-05 24.6 1.2 1.6 1 1 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain PBP1_TM PF14812.1 ETO22536.1 - 0.0006 20.0 1.3 0.0006 20.0 0.9 3.4 3 1 0 3 3 3 1 Transmembrane domain of transglycosylase PBP1 at N-terminal RGM_N PF06535.7 ETO22536.1 - 0.82 9.6 13.2 2.4 8.1 2.1 2.5 2 1 0 2 2 2 0 Repulsive guidance molecule (RGM) N-terminus MIP-T3 PF10243.4 ETO22536.1 - 0.92 7.9 44.1 0.079 11.4 15.1 2.2 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Colicin_Pyocin PF01320.13 ETO22537.1 - 0.065 13.0 2.1 2.6 7.9 0.4 2.5 1 1 1 2 2 2 0 Colicin immunity protein / pyocin immunity protein DcpS_C PF11969.3 ETO22537.1 - 0.18 12.0 3.0 0.16 12.1 0.3 1.9 2 0 0 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding TFIIB PF00382.14 ETO22538.1 - 7.3e-17 60.9 0.4 3.5e-13 49.1 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 ETO22538.1 - 6.7e-06 26.2 15.9 1.4e-05 25.2 2.2 2.6 2 0 0 2 2 2 2 Brf1-like TBP-binding domain SR-25 PF10500.4 ETO22538.1 - 1.6e-05 24.5 10.9 4.4e-05 23.0 7.6 1.7 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Cyclin_N PF00134.18 ETO22538.1 - 0.0007 19.1 3.6 0.01 15.4 0.0 2.7 3 0 0 3 3 3 1 Cyclin, N-terminal domain DUF3874 PF12990.2 ETO22538.1 - 0.013 15.6 0.2 0.049 13.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknonw function from B. Theta Gene description (DUF3874) ETRAMP PF09716.5 ETO22538.1 - 0.3 11.0 1.4 0.91 9.5 0.9 1.8 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) ANTH PF07651.11 ETO22539.1 - 0.029 13.0 3.5 0.51 8.9 0.4 2.2 2 0 0 2 2 2 0 ANTH domain NAD_binding_5 PF07994.7 ETO22539.1 - 0.042 13.3 0.2 0.068 12.6 0.1 1.2 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase DUF809 PF05663.6 ETO22539.1 - 0.11 12.4 4.0 0.12 12.3 1.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF809) zf-DHHC PF01529.15 ETO22540.1 - 0.0011 18.3 5.7 0.0019 17.6 3.9 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF3278 PF11683.3 ETO22540.1 - 0.003 17.5 2.9 0.003 17.5 2.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF3278) DUF1510 PF07423.6 ETO22540.1 - 0.0062 15.9 0.1 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) 7TM_GPCR_Srv PF10323.4 ETO22540.1 - 0.014 14.5 11.0 0.0095 15.0 5.1 1.8 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv MLANA PF14991.1 ETO22540.1 - 0.021 14.8 0.1 0.043 13.8 0.1 1.5 1 0 0 1 1 1 0 Protein melan-A DUF4381 PF14316.1 ETO22540.1 - 0.027 14.5 0.1 0.048 13.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF2370 PF10176.4 ETO22540.1 - 0.029 13.7 2.5 0.041 13.2 1.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2370) O-antigen_lig PF13425.1 ETO22540.1 - 0.048 13.6 0.2 0.066 13.1 0.1 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein YajC PF02699.10 ETO22540.1 - 0.091 12.4 0.2 0.091 12.4 0.1 2.7 2 1 2 4 4 4 0 Preprotein translocase subunit DUF2232 PF09991.4 ETO22540.1 - 0.1 11.5 3.1 0.14 11.1 1.8 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2232) Sex_peptide PF08138.6 ETO22540.1 - 0.15 11.9 2.2 0.59 10.0 0.1 2.6 3 0 0 3 3 3 0 Sex peptide (SP) family FUN14 PF04930.10 ETO22540.1 - 0.38 11.0 2.4 0.49 10.7 0.7 2.0 2 1 0 2 2 2 0 FUN14 family DUF4609 PF15382.1 ETO22540.1 - 0.5 10.1 4.9 0.19 11.4 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4609) DUF4293 PF14126.1 ETO22540.1 - 0.54 10.1 5.0 0.68 9.8 2.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) DUF3139 PF11337.3 ETO22540.1 - 1.2 9.4 7.1 0.9 9.8 1.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3139) DUF912 PF06024.7 ETO22540.1 - 5.4 7.1 10.2 0.77 9.8 1.7 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) AMP-binding PF00501.23 ETO22541.1 - 8.4e-24 83.7 0.0 1.4e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Mss4 PF04421.8 ETO22541.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Mss4 protein RGS PF00615.14 ETO22543.1 - 2.9e-10 40.2 0.1 1.6e-09 37.8 0.0 2.0 1 1 0 1 1 1 1 Regulator of G protein signaling domain rve_3 PF13683.1 ETO22543.1 - 0.00086 18.7 0.2 0.0018 17.7 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain NAAA-beta PF15508.1 ETO22544.1 - 7.4e-06 26.2 0.7 4.9e-05 23.5 0.2 2.5 2 1 1 3 3 3 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase SAE2 PF08573.5 ETO22545.1 - 5e-07 30.3 0.2 5e-07 30.3 0.2 4.0 2 2 1 3 3 3 2 DNA repair protein endonuclease SAE2/CtIP C-terminus V_ATPase_I PF01496.14 ETO22545.1 - 0.18 9.5 9.1 0.23 9.2 6.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF763 PF05559.6 ETO22545.1 - 0.64 8.9 3.7 0.66 8.8 1.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF763) Pept_tRNA_hydro PF01195.14 ETO22547.1 - 3.1e-18 65.9 0.2 5.9e-18 65.0 0.2 1.4 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase SF3b10 PF07189.6 ETO22547.1 - 0.013 15.2 0.1 0.027 14.3 0.0 1.5 2 0 0 2 2 2 0 Splicing factor 3B subunit 10 (SF3b10) zf-CCCH PF00642.19 ETO22548.1 - 0.0069 16.0 1.3 0.0069 16.0 0.9 4.5 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ribosomal_L1 PF00687.16 ETO22549.1 - 6e-13 48.6 1.7 9.5e-13 47.9 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family RP-C_C PF11800.3 ETO22550.1 - 0.045 13.4 2.7 0.073 12.7 1.9 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region HAUS6_N PF14661.1 ETO22550.1 - 0.15 11.4 6.8 0.28 10.4 4.7 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Exonuc_VII_L PF02601.10 ETO22550.1 - 0.15 11.1 6.1 0.035 13.3 2.1 1.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit OmpH PF03938.9 ETO22550.1 - 0.24 11.3 11.4 0.48 10.3 7.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TINF2_N PF14973.1 ETO22550.1 - 0.26 11.4 9.3 0.082 13.0 4.3 1.7 2 0 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus APG6 PF04111.7 ETO22550.1 - 0.34 9.9 11.6 0.59 9.1 8.0 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 COesterase PF00135.23 ETO22550.1 - 0.4 9.3 4.0 0.56 8.8 2.8 1.1 1 0 0 1 1 1 0 Carboxylesterase family DUF4092 PF13322.1 ETO22550.1 - 0.43 10.3 2.7 0.84 9.3 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4092) UvrD-helicase PF00580.16 ETO22550.1 - 0.45 9.7 10.0 0.28 10.4 5.0 1.8 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain HSP70 PF00012.15 ETO22550.1 - 0.74 7.6 11.8 1.3 6.8 8.2 1.3 1 0 0 1 1 1 0 Hsp70 protein V_ATPase_I PF01496.14 ETO22550.1 - 0.97 7.2 6.2 1.4 6.6 4.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RRF PF01765.14 ETO22550.1 - 1 8.7 10.3 2.2 7.6 7.2 1.6 1 0 0 1 1 1 0 Ribosome recycling factor DUF342 PF03961.8 ETO22550.1 - 1.7 6.9 9.2 3.2 6.0 6.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Mst1_SARAH PF11629.3 ETO22550.1 - 2.7 7.8 9.7 5.6 6.8 0.5 2.5 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 Z1 PF10593.4 ETO22550.1 - 4.8 6.3 9.5 8.6 5.4 6.2 1.6 1 1 0 1 1 1 0 Z1 domain ATP-synt_B PF00430.13 ETO22550.1 - 5.8 6.7 13.2 12 5.6 9.1 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) TBPIP PF07106.8 ETO22550.1 - 8.1 5.9 17.8 0.15 11.6 6.8 2.0 3 0 0 3 3 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ApoL PF05461.6 ETO22550.1 - 8.8 5.4 9.5 2.7 7.1 4.5 1.7 2 0 0 2 2 2 0 Apolipoprotein L DUF972 PF06156.8 ETO22550.1 - 9.2 6.6 15.5 0.7 10.2 6.6 2.1 3 0 0 3 3 2 0 Protein of unknown function (DUF972) DUF4633 PF15464.1 ETO22552.1 - 0.29 11.0 0.4 0.51 10.1 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) M20_dimer PF07687.9 ETO22553.1 - 1.2e-09 37.8 0.0 1.6e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 ETO22553.1 - 7.7e-07 28.8 0.0 7.7e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Ribonuc_2-5A PF06479.7 ETO22553.1 - 0.09 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease 2-5A G10 PF01125.12 ETO22554.1 - 0.0028 17.2 0.0 0.006 16.1 0.0 1.5 1 0 0 1 1 1 1 G10 protein Ribosomal_L17 PF01196.14 ETO22554.1 - 0.12 12.9 0.4 0.52 10.9 0.0 2.3 3 0 0 3 3 3 0 Ribosomal protein L17 Spc42p PF11544.3 ETO22555.1 - 0.013 15.3 1.2 0.034 14.0 0.9 1.6 1 0 0 1 1 1 0 Spindle pole body component Spc42p UEV PF05743.8 ETO22555.1 - 0.035 13.7 0.0 0.089 12.4 0.0 1.6 1 0 0 1 1 1 0 UEV domain Geminin PF07412.7 ETO22555.1 - 0.077 12.6 0.4 0.096 12.3 0.3 1.1 1 0 0 1 1 1 0 Geminin CCDC-167 PF15188.1 ETO22555.1 - 0.094 12.6 0.5 0.19 11.6 0.1 1.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 PH PF00169.24 ETO22556.1 - 2.5e-12 46.9 0.6 6.1e-12 45.6 0.4 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 ETO22556.1 - 2.4e-08 33.9 0.4 7.4e-08 32.3 0.2 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.1 ETO22556.1 - 0.00012 22.2 2.3 0.00012 22.2 1.6 3.0 2 2 1 3 3 3 1 Pleckstrin homology domain PH_6 PF15406.1 ETO22556.1 - 0.00081 19.4 0.0 0.0023 17.9 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Mcp5_PH PF12814.2 ETO22556.1 - 0.013 15.4 0.3 0.045 13.6 0.2 1.9 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology DUF342 PF03961.8 ETO22556.1 - 0.059 11.7 7.1 0.11 10.9 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF482 PF04339.7 ETO22556.1 - 0.09 11.6 2.7 0.16 10.8 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF482 ATG16 PF08614.6 ETO22556.1 - 0.1 12.4 20.5 1.7 8.3 11.3 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Y_phosphatase3 PF13350.1 ETO22556.1 - 0.98 9.6 5.5 1.9 8.7 3.8 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family V_ATPase_I PF01496.14 ETO22556.1 - 1.2 6.9 10.3 1.8 6.3 7.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaG PF03646.10 ETO22556.1 - 1.4 9.1 13.6 0.31 11.1 5.4 2.7 1 1 1 2 2 2 0 FlaG protein Transglut_prok PF09017.5 ETO22556.1 - 1.6 7.8 6.8 2.9 6.9 4.7 1.4 1 0 0 1 1 1 0 Microbial transglutaminase APG6 PF04111.7 ETO22556.1 - 2 7.3 16.8 3.5 6.5 11.7 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 FAM176 PF14851.1 ETO22556.1 - 6.7 6.3 9.1 17 5.0 6.3 1.8 1 0 0 1 1 1 0 FAM176 family DUF2015 PF09435.5 ETO22558.1 - 0.08 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2015) Maf PF02545.9 ETO22559.1 - 4.7e-54 182.4 0.0 5.8e-54 182.1 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein Aldedh PF00171.17 ETO22561.1 - 1.1e-10 40.4 2.3 6.4e-05 21.4 0.0 3.1 3 0 0 3 3 3 3 Aldehyde dehydrogenase family DEAD PF00270.24 ETO22562.1 - 5.9e-47 159.3 0.0 3e-46 156.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETO22562.1 - 6.9e-29 99.5 0.0 5.5e-28 96.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 ETO22562.1 - 0.029 12.7 0.0 2.3 6.5 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1253) Vps39_2 PF10367.4 ETO22563.1 - 6.7e-18 64.8 0.8 2.4e-17 63.0 0.1 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Sulfatase PF00884.18 ETO22564.1 - 3.4e-23 82.2 0.0 5.4e-23 81.6 0.0 1.3 1 1 0 1 1 1 1 Sulfatase Stn1 PF10451.4 ETO22565.1 - 0.00045 19.1 2.3 0.00056 18.8 1.6 1.2 1 0 0 1 1 1 1 Telomere regulation protein Stn1 ATG16 PF08614.6 ETO22565.1 - 0.014 15.2 7.8 0.023 14.5 5.4 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) AAA_23 PF13476.1 ETO22565.1 - 0.023 15.0 1.7 0.028 14.7 1.2 1.1 1 0 0 1 1 1 0 AAA domain HAUS6_N PF14661.1 ETO22565.1 - 0.069 12.5 3.1 0.088 12.1 2.2 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Cluap1 PF10234.4 ETO22565.1 - 0.081 12.1 4.9 0.1 11.7 3.4 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 bZIP_2 PF07716.10 ETO22565.1 - 0.46 10.3 5.8 1 9.2 4.0 1.6 1 0 0 1 1 1 0 Basic region leucine zipper DUF972 PF06156.8 ETO22565.1 - 0.49 10.7 7.4 0.22 11.8 2.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) bZIP_1 PF00170.16 ETO22565.1 - 0.91 9.5 3.8 0.37 10.7 0.7 1.7 2 0 0 2 2 2 0 bZIP transcription factor Helitron_like_N PF14214.1 ETO22566.1 - 0.029 14.0 1.6 0.052 13.2 1.1 1.4 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus YjgP_YjgQ PF03739.9 ETO22566.1 - 2.7 6.6 4.9 3.8 6.1 3.4 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family PP2C PF00481.16 ETO22567.1 - 0.066 12.5 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 2C Gemini_mov PF01708.11 ETO22568.1 - 0.19 11.3 1.8 0.25 10.9 0.1 2.0 2 0 0 2 2 2 0 Geminivirus putative movement protein CDC45 PF02724.9 ETO22570.1 - 0.033 12.2 14.8 0.035 12.1 10.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 ETO22570.1 - 0.036 12.0 20.2 0.037 11.9 14.0 1.0 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.11 ETO22570.1 - 1.1 8.2 7.6 1.1 8.1 5.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sigma70_ner PF04546.8 ETO22570.1 - 1.2 8.7 14.1 1.5 8.3 9.8 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleo_P87 PF07267.6 ETO22570.1 - 1.2 7.7 6.9 1.6 7.3 4.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 U79_P34 PF03064.11 ETO22570.1 - 2.1 7.7 15.5 2.5 7.5 10.7 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Nucleoplasmin PF03066.10 ETO22570.1 - 4 6.9 15.2 7 6.1 10.6 1.5 1 0 0 1 1 1 0 Nucleoplasmin Pkinase PF00069.20 ETO22571.1 - 0.0093 15.1 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain 2OG-FeII_Oxy PF03171.15 ETO22571.1 - 0.03 14.6 0.0 0.062 13.6 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily tRNA-synt_1d PF00750.14 ETO22572.1 - 1e-17 63.9 0.8 1.4e-17 63.5 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (R) Arg_tRNA_synt_N PF03485.11 ETO22572.1 - 8.1e-05 23.0 0.0 0.00017 22.0 0.0 1.5 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA_bind PF01588.15 ETO22572.1 - 0.0014 18.4 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain MADF_DNA_bdg PF10545.4 ETO22574.1 - 0.015 15.5 5.7 0.26 11.5 0.2 2.6 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF2413 PF10310.4 ETO22575.1 - 0.2 10.4 10.0 0.23 10.2 6.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) RR_TM4-6 PF06459.7 ETO22575.1 - 4.3 7.1 7.5 5.1 6.9 5.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mito_carr PF00153.22 ETO22576.1 - 2.1e-27 94.6 0.1 2.3e-18 65.6 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein HAMP PF00672.20 ETO22576.1 - 0.0041 17.2 0.1 0.018 15.2 0.0 2.0 2 0 0 2 2 2 1 HAMP domain MMR1 PF08505.5 ETO22577.1 - 0.069 13.1 13.9 0.08 12.9 9.6 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein CDK2AP PF09806.4 ETO22577.1 - 0.36 11.0 8.6 0.45 10.7 6.0 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Apis_Csd PF11671.3 ETO22577.1 - 0.82 9.4 16.9 1 9.1 11.7 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein Pox_Ag35 PF03286.9 ETO22577.1 - 0.97 8.9 14.0 1.2 8.6 9.7 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Tim54 PF11711.3 ETO22577.1 - 2.9 6.3 10.2 3.4 6.1 7.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.12 ETO22577.1 - 3.5 6.3 8.1 3.6 6.3 5.6 1.0 1 0 0 1 1 1 0 Presenilin Spore_YhcN_YlaJ PF09580.5 ETO22577.1 - 7.4 6.6 18.4 9.2 6.3 12.8 1.2 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Zip PF02535.17 ETO22577.1 - 7.5 5.4 5.6 8.1 5.3 3.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Paramyxo_ncap PF00973.14 ETO22577.1 - 8.8 4.8 8.3 10 4.7 5.8 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein adh_short PF00106.20 ETO22578.1 - 1.7e-07 31.3 0.2 4e-07 30.0 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 ETO22578.1 - 0.00012 21.6 0.1 0.00044 19.7 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 ETO22578.1 - 0.051 13.2 0.0 0.095 12.3 0.0 1.5 1 0 0 1 1 1 0 KR domain zf-Tim10_DDP PF02953.10 ETO22578.1 - 0.055 12.7 6.4 0.23 10.7 0.4 3.0 3 0 0 3 3 3 0 Tim10/DDP family zinc finger Serglycin PF04360.7 ETO22579.1 - 0.0059 16.3 0.2 0.013 15.1 0.1 1.6 1 0 0 1 1 1 1 Serglycin Apis_Csd PF11671.3 ETO22579.1 - 0.15 11.8 31.1 0.068 12.9 6.8 2.5 2 0 0 2 2 2 0 Complementary sex determiner protein Eapp_C PF10238.4 ETO22579.1 - 1 9.2 26.1 2.1 8.2 4.3 2.7 3 0 0 3 3 3 0 E2F-associated phosphoprotein Menin PF05053.8 ETO22579.1 - 1.3 7.1 12.8 0.67 8.0 1.0 2.2 2 0 0 2 2 2 0 Menin Pox_Ag35 PF03286.9 ETO22579.1 - 1.4 8.4 14.6 0.065 12.7 1.1 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Methyltransf_12 PF08242.7 ETO22579.1 - 2.7 8.5 13.7 4.9 7.7 0.6 3.2 3 0 0 3 3 3 0 Methyltransferase domain Ion_trans PF00520.26 ETO22580.1 - 2.1e-13 49.9 15.2 7.3e-13 48.2 5.8 2.2 2 0 0 2 2 2 2 Ion transport protein DUF543 PF04418.7 ETO22580.1 - 0.11 12.4 0.0 0.31 11.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF543) DUF2207 PF09972.4 ETO22580.1 - 0.92 8.0 8.1 0.093 11.3 2.1 1.7 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Ion_trans PF00520.26 ETO22581.1 - 0.00071 18.8 6.9 0.00071 18.8 4.8 2.5 3 0 0 3 3 3 1 Ion transport protein YajC PF02699.10 ETO22583.1 - 0.046 13.3 4.8 1.3 8.7 0.2 2.9 3 0 0 3 3 3 0 Preprotein translocase subunit YMF19 PF02326.10 ETO22583.1 - 0.93 10.1 8.2 1.6 9.3 0.4 3.5 4 0 0 4 4 4 0 Plant ATP synthase F0 NAC PF01849.13 ETO22584.1 - 8.8e-11 41.1 0.3 4.3e-10 38.9 0.1 1.9 2 0 0 2 2 2 1 NAC domain TIP120 PF08623.5 ETO22584.1 - 0.00085 18.9 0.3 0.0009 18.8 0.2 1.1 1 0 0 1 1 1 1 TATA-binding protein interacting (TIP20) PHD PF00628.24 ETO22587.1 - 0.0043 16.6 9.0 0.0043 16.6 6.2 2.2 2 0 0 2 2 2 1 PHD-finger Rifin_STEVOR PF02009.11 ETO22587.1 - 0.011 15.4 0.4 0.048 13.2 0.1 1.9 2 0 0 2 2 2 0 Rifin/stevor family C1_2 PF03107.11 ETO22587.1 - 0.026 14.6 7.6 0.064 13.3 5.3 1.7 1 0 0 1 1 1 0 C1 domain DUF3753 PF12575.3 ETO22587.1 - 0.04 13.7 1.5 0.04 13.7 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) NinF PF05810.7 ETO22587.1 - 0.052 13.3 0.3 0.16 11.8 0.2 1.8 1 0 0 1 1 1 0 NinF protein zf-HC5HC2H PF13771.1 ETO22587.1 - 0.06 13.5 7.4 0.16 12.1 2.5 2.5 2 0 0 2 2 2 0 PHD-like zinc-binding domain Peptidase_A4 PF01828.12 ETO22589.1 - 3.2e-05 23.0 7.6 5.8e-05 22.2 5.3 1.5 1 1 0 1 1 1 1 Peptidase A4 family Neur_chan_LBD PF02931.18 ETO22591.1 - 0.0019 17.3 0.1 0.0025 17.0 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain cobW PF02492.14 ETO22592.1 - 5.3e-27 94.4 1.0 1.4e-12 47.4 0.1 2.6 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 ETO22592.1 - 2.4e-24 84.8 0.0 4e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain PUB PF09409.5 ETO22594.1 - 1.1e-06 28.3 0.3 2.4e-06 27.1 0.2 1.6 1 0 0 1 1 1 1 PUB domain ETRAMP PF09716.5 ETO22594.1 - 0.0073 16.2 0.5 5.1 7.1 0.5 2.7 2 2 0 2 2 2 2 Malarial early transcribed membrane protein (ETRAMP) FAM117 PF15388.1 ETO22595.1 - 0.1 11.8 3.2 0.16 11.1 2.2 1.3 1 0 0 1 1 1 0 Protein Family FAM117 PspB PF06667.7 ETO22595.1 - 0.49 10.3 2.4 0.66 9.9 0.0 2.4 2 0 0 2 2 2 0 Phage shock protein B BCAS2 PF05700.6 ETO22595.1 - 1.4 8.2 6.9 0.13 11.7 1.2 1.8 2 0 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) CARM1 PF11531.3 ETO22596.1 - 0.002 17.8 1.0 0.006 16.2 0.7 1.8 1 0 0 1 1 1 1 Coactivator-associated arginine methyltransferase 1 N terminal SRP54_N PF02881.14 ETO22596.1 - 0.036 14.1 1.8 0.11 12.5 0.1 2.6 3 0 0 3 3 3 0 SRP54-type protein, helical bundle domain UBA PF00627.26 ETO22596.1 - 0.071 12.9 0.1 1.3 8.9 0.0 2.5 2 0 0 2 2 2 0 UBA/TS-N domain Amidohydro_1 PF01979.15 ETO22597.1 - 9.1e-08 32.1 0.0 1.1e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.9 ETO22597.1 - 0.092 12.2 0.0 0.13 11.8 0.0 1.4 1 1 0 1 1 1 0 Amidohydrolase DUF1162 PF06650.7 ETO22598.1 - 2.8e-20 72.6 1.8 2e-11 43.6 0.0 5.0 3 2 1 4 4 4 4 Protein of unknown function (DUF1162) ATG_C PF09333.6 ETO22598.1 - 2.9e-06 27.3 0.0 6.5e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 ATG C terminal domain Aa_trans PF01490.13 ETO22599.1 - 1.7e-34 119.0 29.1 3.3e-34 118.0 20.2 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Pectate_lyase_3 PF12708.2 ETO22600.1 - 1.4e-13 51.4 8.6 1.4e-13 51.4 6.0 2.5 1 1 1 2 2 2 1 Pectate lyase superfamily protein Beta_helix PF13229.1 ETO22600.1 - 0.00025 20.8 46.9 0.2 11.4 5.0 3.5 1 1 2 3 3 3 2 Right handed beta helix region DUF948 PF06103.6 ETO22601.1 - 2.5e-05 24.0 3.8 5.5e-05 22.9 2.6 1.6 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) DUF4337 PF14235.1 ETO22601.1 - 7.6e-05 22.5 0.3 0.0001 22.1 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4337) RmuC PF02646.11 ETO22601.1 - 0.00013 20.9 1.7 0.00019 20.3 1.1 1.2 1 0 0 1 1 1 1 RmuC family DUF3829 PF12889.2 ETO22601.1 - 0.00022 20.4 3.2 0.00028 20.1 2.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3829) Laminin_II PF06009.7 ETO22601.1 - 0.00025 20.8 5.5 0.00038 20.2 3.8 1.3 1 0 0 1 1 1 1 Laminin Domain II APG17 PF04108.7 ETO22601.1 - 0.00051 18.9 1.4 0.00051 18.9 1.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF1664 PF07889.7 ETO22601.1 - 0.00095 18.9 2.0 0.0019 18.0 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) CorA PF01544.13 ETO22601.1 - 0.0018 17.3 1.3 0.23 10.4 0.1 2.2 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein MCPsignal PF00015.16 ETO22601.1 - 0.0024 17.4 8.5 0.0036 16.8 5.9 1.2 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Laminin_I PF06008.9 ETO22601.1 - 0.0044 16.3 3.2 0.0063 15.8 2.2 1.2 1 0 0 1 1 1 1 Laminin Domain I TelA PF05816.6 ETO22601.1 - 0.0049 15.6 4.8 0.0049 15.6 3.4 1.5 2 0 0 2 2 2 1 Toxic anion resistance protein (TelA) AATF-Che1 PF13339.1 ETO22601.1 - 0.0053 16.9 3.1 0.075 13.1 2.1 2.2 1 1 0 1 1 1 1 Apoptosis antagonizing transcription factor Cauli_AT PF03233.8 ETO22601.1 - 0.0065 16.1 0.4 0.0088 15.7 0.3 1.3 1 0 0 1 1 1 1 Aphid transmission protein DUF812 PF05667.6 ETO22601.1 - 0.0068 14.9 4.6 0.008 14.7 3.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF2317 PF10079.4 ETO22601.1 - 0.0093 14.6 1.7 0.011 14.4 1.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2317) DUF848 PF05852.6 ETO22601.1 - 0.0094 15.8 4.2 0.013 15.3 2.9 1.2 1 0 0 1 1 1 1 Gammaherpesvirus protein of unknown function (DUF848) Syntaxin-6_N PF09177.6 ETO22601.1 - 0.011 16.0 2.2 0.011 16.0 1.5 2.3 2 1 1 3 3 2 0 Syntaxin 6, N-terminal WXG100 PF06013.7 ETO22601.1 - 0.013 15.5 0.7 0.33 10.9 0.5 2.3 1 1 0 1 1 1 0 Proteins of 100 residues with WXG GldM_N PF12081.3 ETO22601.1 - 0.014 14.9 3.6 0.036 13.5 2.4 1.8 1 1 0 1 1 1 0 GldM N-terminal domain Med21 PF11221.3 ETO22601.1 - 0.014 15.3 0.3 0.027 14.4 0.2 1.4 1 0 0 1 1 1 0 Subunit 21 of Mediator complex COG2 PF06148.6 ETO22601.1 - 0.015 15.2 1.8 0.024 14.4 1.2 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 ApoLp-III PF07464.6 ETO22601.1 - 0.02 14.9 5.3 0.033 14.2 3.7 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) TMP_2 PF06791.8 ETO22601.1 - 0.023 14.2 2.6 0.035 13.7 1.8 1.2 1 0 0 1 1 1 0 Prophage tail length tape measure protein Acyl-CoA_dh_C PF12806.2 ETO22601.1 - 0.024 14.4 2.4 0.062 13.1 1.2 1.8 1 1 1 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like CENP-F_leu_zip PF10473.4 ETO22601.1 - 0.026 14.4 6.4 0.026 14.4 4.4 1.8 2 0 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1129 PF06570.6 ETO22601.1 - 0.054 12.8 1.0 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) NEP PF10167.4 ETO22601.1 - 0.054 13.1 0.7 0.09 12.4 0.5 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein BROMI PF14961.1 ETO22601.1 - 0.059 10.5 0.0 0.088 9.9 0.0 1.3 1 0 0 1 1 1 0 Broad-minded protein Ferritin PF00210.19 ETO22601.1 - 0.06 13.0 3.0 0.091 12.5 2.1 1.3 1 0 0 1 1 1 0 Ferritin-like domain DUF2897 PF11446.3 ETO22601.1 - 0.071 12.9 0.5 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) Hormone_1 PF00103.15 ETO22601.1 - 0.072 12.4 0.3 0.11 11.8 0.2 1.3 1 0 0 1 1 1 0 Somatotropin hormone family RE_NgoFVII PF09565.5 ETO22601.1 - 0.073 12.0 3.9 0.1 11.5 2.7 1.1 1 0 0 1 1 1 0 NgoFVII restriction endonuclease FlgN PF05130.7 ETO22601.1 - 0.084 13.1 0.9 0.13 12.4 0.6 1.2 1 0 0 1 1 1 0 FlgN protein DUF935 PF06074.7 ETO22601.1 - 0.088 11.5 5.1 0.11 11.1 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF935) FbpA PF05833.6 ETO22601.1 - 0.095 11.2 3.3 0.13 10.7 2.3 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF1628 PF07790.6 ETO22601.1 - 0.095 13.4 0.1 0.18 12.5 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1628) MscS_porin PF12795.2 ETO22601.1 - 0.1 11.9 0.6 0.15 11.3 0.4 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain YtxH PF12732.2 ETO22601.1 - 0.12 12.8 11.6 2.1 8.7 8.0 2.3 1 1 0 1 1 1 0 YtxH-like protein Sipho_Gp157 PF05565.6 ETO22601.1 - 0.12 11.9 7.8 0.2 11.2 5.4 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 Pex24p PF06398.6 ETO22601.1 - 0.14 10.9 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Filo_VP35 PF02097.10 ETO22601.1 - 0.15 11.2 2.1 0.19 10.9 1.5 1.1 1 0 0 1 1 1 0 Filoviridae VP35 Reo_sigmaC PF04582.7 ETO22601.1 - 0.17 11.0 1.3 0.21 10.7 0.9 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein APG6 PF04111.7 ETO22601.1 - 0.2 10.6 5.9 0.26 10.2 4.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DASH_Duo1 PF08651.5 ETO22601.1 - 0.22 11.0 1.7 1.7 8.2 1.1 2.2 1 1 0 1 1 1 0 DASH complex subunit Duo1 LUC7 PF03194.10 ETO22601.1 - 0.26 10.8 4.7 0.31 10.5 3.3 1.2 1 0 0 1 1 1 0 LUC7 N_terminus ATP-synt_B PF00430.13 ETO22601.1 - 0.26 11.0 5.5 0.46 10.2 3.8 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Fib_alpha PF08702.5 ETO22601.1 - 0.27 11.3 2.2 0.56 10.3 1.6 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family EspB PF05802.6 ETO22601.1 - 0.32 9.9 4.5 0.42 9.5 3.1 1.1 1 0 0 1 1 1 0 Enterobacterial EspB protein V_ATPase_I PF01496.14 ETO22601.1 - 0.34 8.7 6.0 0.3 8.8 3.7 1.2 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4330 PF14221.1 ETO22601.1 - 0.35 10.6 2.8 1.3 8.8 2.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4330) IncA PF04156.9 ETO22601.1 - 0.37 10.3 4.8 0.067 12.7 0.5 1.7 2 0 0 2 2 2 0 IncA protein Seryl_tRNA_N PF02403.17 ETO22601.1 - 0.41 10.6 6.4 0.36 10.8 2.8 1.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain FlaC_arch PF05377.6 ETO22601.1 - 0.42 10.5 8.6 1 9.3 4.6 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Prominin PF05478.6 ETO22601.1 - 0.44 8.0 5.9 0.34 8.3 2.0 1.9 1 1 1 2 2 2 0 Prominin DUF883 PF05957.8 ETO22601.1 - 0.49 10.8 6.5 3 8.3 4.5 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) TMPIT PF07851.8 ETO22601.1 - 0.5 9.3 4.5 0.41 9.6 1.8 1.7 2 0 0 2 2 2 0 TMPIT-like protein Syntaxin PF00804.20 ETO22601.1 - 0.63 10.2 3.2 1.9 8.6 2.2 1.8 1 1 0 1 1 1 0 Syntaxin NPV_P10 PF05531.7 ETO22601.1 - 0.69 10.2 3.8 1.3 9.3 2.7 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Med9 PF07544.8 ETO22601.1 - 0.76 9.5 6.0 2.9 7.6 1.9 2.3 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Chlorosome_CsmC PF11098.3 ETO22601.1 - 0.84 9.3 5.5 1.9 8.1 3.8 1.6 1 1 0 1 1 1 0 Chlorosome envelope protein C Prefoldin_2 PF01920.15 ETO22601.1 - 1.7 8.4 9.0 11 5.8 6.3 2.2 1 1 0 1 1 1 0 Prefoldin subunit ISG65-75 PF11727.3 ETO22601.1 - 2.1 7.3 9.8 4.7 6.1 6.8 1.5 1 1 0 1 1 1 0 Invariant surface glycoprotein DUF2205 PF10224.4 ETO22601.1 - 2.5 7.7 5.5 5 6.7 1.3 2.2 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) FYDLN_acid PF09538.5 ETO22601.1 - 2.9 8.5 12.1 4.1 8.0 8.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF241 PF03087.9 ETO22601.1 - 3.5 7.0 6.4 5.7 6.3 4.5 1.4 1 1 0 1 1 1 0 Arabidopsis protein of unknown function DUF3647 PF12363.3 ETO22601.1 - 5.2 7.2 8.7 5.3 7.1 4.1 2.1 1 1 1 2 2 2 0 Phage protein DUF4446 PF14584.1 ETO22601.1 - 7.2 6.4 7.2 26 4.6 4.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) BLOC1_2 PF10046.4 ETO22601.1 - 8.8 6.5 10.4 1.9 8.6 4.3 2.0 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Arf PF00025.16 ETO22604.1 - 1e-51 174.6 0.0 1.7e-49 167.4 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 ETO22604.1 - 3.4e-09 35.8 0.1 3e-06 26.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 ETO22604.1 - 5.4e-08 33.3 0.0 8.9e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 ETO22604.1 - 3.6e-07 29.5 0.0 5.2e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 ETO22604.1 - 4.4e-07 29.4 0.0 6.1e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 ETO22604.1 - 5.3e-07 29.5 0.0 9e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 ETO22604.1 - 6.3e-05 22.4 0.1 0.024 14.0 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 ETO22604.1 - 0.0015 17.7 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 ETO22604.1 - 0.021 14.1 0.0 0.036 13.3 0.0 1.5 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.4 ETO22604.1 - 0.026 14.0 0.0 0.11 12.0 0.0 1.9 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Campylo_MOMP PF05538.6 ETO22604.1 - 0.032 12.6 0.0 0.038 12.3 0.0 1.2 1 1 0 1 1 1 0 Campylobacter major outer membrane protein AAA_22 PF13401.1 ETO22604.1 - 0.086 12.9 0.0 0.84 9.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 ETO22604.1 - 0.11 12.0 0.1 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MtN3_slv PF03083.11 ETO22605.1 - 0.092 12.6 1.3 0.91 9.4 0.2 2.3 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange RabGAP-TBC PF00566.13 ETO22606.1 - 3.2e-07 30.0 0.4 3.2e-07 30.0 0.3 3.1 3 0 0 3 3 3 1 Rab-GTPase-TBC domain FimP PF09766.4 ETO22606.1 - 0.14 11.2 8.0 0.19 10.7 5.5 1.1 1 0 0 1 1 1 0 Fms-interacting protein Folate_carrier PF01770.13 ETO22606.1 - 0.15 10.5 1.7 0.24 9.8 1.2 1.2 1 0 0 1 1 1 0 Reduced folate carrier Pex14_N PF04695.8 ETO22606.1 - 0.24 11.4 5.8 0.29 11.2 3.5 1.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pox_Ag35 PF03286.9 ETO22606.1 - 1.3 8.4 9.2 2.2 7.7 6.4 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NRDE-2 PF08424.5 ETO22606.1 - 7 5.4 12.1 13 4.5 8.4 1.4 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference PPR_2 PF13041.1 ETO22607.1 - 2.4e-08 33.7 3.3 9.3e-07 28.7 0.4 2.9 1 1 2 3 3 3 2 PPR repeat family PPR PF01535.15 ETO22607.1 - 7.4e-07 28.7 3.4 0.0092 15.8 0.1 3.4 3 0 0 3 3 3 2 PPR repeat PPR_3 PF13812.1 ETO22607.1 - 7.6e-07 28.9 0.2 0.38 11.1 0.0 3.6 3 0 0 3 3 3 2 Pentatricopeptide repeat domain ATP13 PF12921.2 ETO22607.1 - 0.00016 21.0 1.1 0.039 13.3 0.2 2.8 1 1 2 3 3 3 2 Mitochondrial ATPase expression PPR_1 PF12854.2 ETO22607.1 - 0.082 12.3 0.0 3 7.3 0.0 2.6 2 0 0 2 2 2 0 PPR repeat ESSS PF10183.4 ETO22608.1 - 1.2 9.5 3.8 1.1 9.7 0.0 2.7 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) PI-PLC-X PF00388.14 ETO22609.1 - 4.1e-05 23.0 0.0 8.8e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Tetraspannin PF00335.15 ETO22610.1 - 0.0042 16.3 4.4 0.0081 15.4 3.1 1.5 1 0 0 1 1 1 1 Tetraspanin family HHV6-IE PF03753.8 ETO22610.1 - 0.017 12.6 19.8 0.018 12.5 13.7 1.0 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein Daxx PF03344.10 ETO22610.1 - 0.044 12.2 21.9 0.054 11.9 15.2 1.1 1 0 0 1 1 1 0 Daxx Family Menin PF05053.8 ETO22610.1 - 0.49 8.4 15.1 0.61 8.1 10.5 1.2 1 0 0 1 1 1 0 Menin Utp14 PF04615.8 ETO22610.1 - 0.8 7.7 32.4 0.95 7.5 22.5 1.0 1 0 0 1 1 1 0 Utp14 protein Hid1 PF12722.2 ETO22610.1 - 4.5 4.8 24.3 5.4 4.5 16.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein UreE_N PF02814.10 ETO22610.1 - 8.2 6.0 5.9 29 4.2 0.2 2.4 2 0 0 2 2 2 0 UreE urease accessory protein, N-terminal domain HEAT PF02985.17 ETO22611.1 - 8.8e-06 25.3 0.1 6.6e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 HEAT repeat HEAT_2 PF13646.1 ETO22611.1 - 0.00068 19.8 0.0 0.0079 16.4 0.0 2.0 2 0 0 2 2 2 1 HEAT repeats Arm PF00514.18 ETO22611.1 - 0.042 13.6 0.0 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 ETO22611.1 - 0.058 13.9 0.0 0.19 12.2 0.0 1.8 2 0 0 2 2 2 0 HEAT-like repeat NPIP PF06409.6 ETO22611.1 - 0.062 12.0 0.0 0.1 11.2 0.0 1.3 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) Pex14_N PF04695.8 ETO22611.1 - 0.1 12.6 0.2 0.4 10.7 0.0 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF106 PF01956.11 ETO22613.1 - 0.25 10.8 2.3 0.46 10.0 1.6 1.5 1 0 0 1 1 1 0 Integral membrane protein DUF106 HECT PF00632.20 ETO22614.1 - 1.5e-59 201.7 0.1 6.7e-58 196.3 0.1 2.2 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Laminin_G_3 PF13385.1 ETO22614.1 - 7.3e-07 29.5 0.0 1.9e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily SPRY PF00622.23 ETO22615.1 - 2.4e-14 53.4 0.2 9.8e-14 51.5 0.1 2.2 2 0 0 2 2 2 1 SPRY domain zf-RanBP PF00641.13 ETO22615.1 - 7.1e-05 21.8 3.9 0.00019 20.4 2.7 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Ribosomal_60s PF00428.14 ETO22615.1 - 0.83 10.0 8.1 5.3 7.5 5.6 2.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Tubulin_C PF03953.12 ETO22616.1 - 5.8e-28 97.4 0.0 9.5e-28 96.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 ETO22616.1 - 5.2e-25 88.5 0.0 8.7e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain tRNA-synt_1c_C PF03950.13 ETO22616.1 - 0.015 15.0 0.0 0.036 13.7 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), anti-codon binding domain Ion_trans_2 PF07885.11 ETO22617.1 - 8.3e-10 38.2 5.1 8.3e-10 38.2 3.5 2.3 2 0 0 2 2 2 1 Ion channel DUF1282 PF06930.7 ETO22617.1 - 0.037 13.6 1.6 0.078 12.6 1.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) Rax2 PF12768.2 ETO22617.1 - 0.089 11.9 0.8 3.5 6.7 0.0 2.2 2 0 0 2 2 2 0 Cortical protein marker for cell polarity Herpes_US9 PF06072.6 ETO22617.1 - 0.25 11.2 5.0 2.6 7.9 0.1 3.2 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 DUF3671 PF12420.3 ETO22617.1 - 0.44 10.5 11.8 5.8 6.9 8.2 2.2 1 1 0 1 1 1 0 Protein of unknown function DUF3290 PF11694.3 ETO22617.1 - 0.67 9.6 3.5 5.9 6.6 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3290) Sigma_reg_N PF13800.1 ETO22617.1 - 3.4 7.7 11.3 3.8 7.6 0.7 3.1 3 0 0 3 3 3 0 Sigma factor regulator N-terminal DUF1510 PF07423.6 ETO22618.1 - 0.001 18.4 3.7 0.0013 18.1 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Ycf1 PF05758.7 ETO22618.1 - 0.012 13.3 1.0 0.014 13.1 0.7 1.0 1 0 0 1 1 1 0 Ycf1 PRTP PF01366.13 ETO22618.1 - 0.017 13.1 0.5 0.022 12.7 0.3 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein DUF1980 PF09323.5 ETO22618.1 - 0.024 14.4 0.7 0.032 13.9 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Acetyltransf_1 PF00583.19 ETO22618.1 - 0.04 13.9 0.0 0.49 10.4 0.0 2.4 2 1 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETO22618.1 - 0.07 13.2 0.0 0.17 12.0 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain CLAG PF03805.8 ETO22618.1 - 0.2 8.9 1.1 0.24 8.6 0.8 1.0 1 0 0 1 1 1 0 Cytoadherence-linked asexual protein Daxx PF03344.10 ETO22618.1 - 0.2 10.0 7.7 0.26 9.7 5.3 1.0 1 0 0 1 1 1 0 Daxx Family S-antigen PF05756.6 ETO22618.1 - 0.41 10.6 4.0 0.81 9.7 2.8 1.5 1 0 0 1 1 1 0 S-antigen protein CDC45 PF02724.9 ETO22618.1 - 1 7.3 4.9 1.2 7.0 3.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.5 ETO22618.1 - 9.8 6.1 12.3 18 5.2 8.5 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Sulfatase PF00884.18 ETO22619.1 - 3.3e-13 49.5 0.1 4.3e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 ETO22619.1 - 0.001 18.4 0.1 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase ETRAMP PF09716.5 ETO22619.1 - 1.5 8.7 5.1 6.3 6.8 3.5 2.0 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Sulfatase PF00884.18 ETO22620.1 - 1.9e-14 53.5 0.3 2.2e-14 53.3 0.2 1.1 1 0 0 1 1 1 1 Sulfatase RFX1_trans_act PF04589.8 ETO22621.1 - 0.031 14.0 1.3 0.037 13.7 0.9 1.2 1 0 0 1 1 1 0 RFX1 transcription activation region ETRAMP PF09716.5 ETO22621.1 - 0.048 13.6 2.2 0.048 13.6 1.5 1.8 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) SseB PF07179.7 ETO22621.1 - 0.16 11.7 1.0 0.28 11.0 0.7 1.3 1 0 0 1 1 1 0 SseB protein N-terminal domain TAF4 PF05236.9 ETO22621.1 - 0.16 11.1 6.6 0.19 10.9 4.6 1.0 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Lin-8 PF03353.10 ETO22621.1 - 0.23 10.6 9.5 0.25 10.5 6.6 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Mem_trans PF03547.13 ETO22621.1 - 0.26 9.5 3.4 0.27 9.5 2.4 1.0 1 0 0 1 1 1 0 Membrane transport protein Peptidase_S64 PF08192.6 ETO22621.1 - 0.48 8.7 5.6 0.47 8.7 3.9 1.0 1 0 0 1 1 1 0 Peptidase family S64 Radial_spoke_3 PF06098.6 ETO22621.1 - 0.5 9.3 8.2 0.6 9.0 5.7 1.1 1 0 0 1 1 1 0 Radial spoke protein 3 Actino_peptide PF14408.1 ETO22621.1 - 1.5 8.8 10.1 5.5 6.9 4.7 2.4 2 0 0 2 2 2 0 Ribosomally synthesized peptide in actinomycetes Dicty_REP PF05086.7 ETO22621.1 - 3.3 5.3 8.7 3.5 5.2 6.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein OPT PF03169.10 ETO22622.1 - 3e-05 22.6 0.2 3.9e-05 22.2 0.2 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Ni_hydr_CYTB PF01292.15 ETO22622.1 - 0.0046 16.3 0.2 0.0082 15.5 0.1 1.4 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 DUF2149 PF09919.4 ETO22622.1 - 0.011 15.8 0.3 0.033 14.2 0.2 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) Nucleoside_tran PF01733.13 ETO22622.1 - 0.025 13.7 0.5 0.073 12.2 0.3 1.7 1 1 0 1 1 1 0 Nucleoside transporter 7tm_1 PF00001.16 ETO22622.1 - 0.037 13.1 4.3 1.3 8.0 0.4 2.3 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) Cytochrom_B_N PF00033.14 ETO22622.1 - 0.18 11.1 3.9 0.92 8.8 1.1 2.0 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB 7TM_GPCR_Srx PF10328.4 ETO22622.1 - 1.4 7.9 13.7 0.018 14.1 2.0 2.2 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF2975 PF11188.3 ETO22622.1 - 1.7 8.3 7.3 4.5 7.0 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) PDR_CDR PF06422.7 ETO22622.1 - 3.1 7.5 6.2 3.7 7.2 0.4 2.9 3 0 0 3 3 3 0 CDR ABC transporter Daxx PF03344.10 ETO22623.1 - 0.45 8.9 17.2 0.48 8.8 11.9 1.1 1 0 0 1 1 1 0 Daxx Family Zip PF02535.17 ETO22623.1 - 0.72 8.8 2.9 0.77 8.7 2.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.9 ETO22623.1 - 0.91 7.4 14.6 1 7.2 10.1 1.1 1 0 0 1 1 1 0 CDC45-like protein GAGA_bind PF06217.7 ETO22623.1 - 1.2 9.0 11.0 1.6 8.6 7.7 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Hid1 PF12722.2 ETO22623.1 - 2.9 5.4 9.4 2.9 5.4 6.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAM75 PF14650.1 ETO22623.1 - 6.3 6.0 9.2 7.8 5.7 6.4 1.0 1 0 0 1 1 1 0 FAM75 family DHHW PF14286.1 ETO22623.1 - 8.2 5.6 9.8 9.4 5.4 6.8 1.3 1 0 0 1 1 1 0 DHHW protein CT47 PF15623.1 ETO22623.1 - 9.6 5.8 23.6 11 5.6 16.4 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 DUF2146 PF10220.4 ETO22623.1 - 9.6 4.0 13.4 12 3.6 9.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) HSP70 PF00012.15 ETO22624.1 - 2.1e-28 98.6 4.7 3.8e-28 97.7 3.2 1.4 1 1 0 1 1 1 1 Hsp70 protein HSP70 PF00012.15 ETO22625.1 - 1.2e-12 46.5 0.1 1.7e-12 46.0 0.1 1.2 1 0 0 1 1 1 1 Hsp70 protein DUF2779 PF11074.3 ETO22625.1 - 0.0024 17.9 1.7 0.083 12.9 0.0 3.6 3 1 0 3 3 3 1 Domain of unknown function(DUF2779) DUF3408 PF11888.3 ETO22626.1 - 0.55 10.1 4.8 0.75 9.7 3.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3408) GCS PF03074.11 ETO22627.1 - 1.1e-103 347.2 0.2 1.2e-103 347.0 0.2 1.0 1 0 0 1 1 1 1 Glutamate-cysteine ligase Sua5_yciO_yrdC PF01300.13 ETO22628.1 - 6e-48 162.4 0.0 1.3e-47 161.3 0.0 1.5 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 ETO22628.1 - 2.3e-09 37.4 0.3 7.8e-09 35.6 0.2 1.9 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding DUF3769 PF12600.3 ETO22630.1 - 0.011 14.5 0.5 0.014 14.2 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3769) DUF3414 PF11894.3 ETO22632.1 - 0.0019 15.2 0.1 0.0021 15.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Ricin_B_lectin PF00652.17 ETO22633.1 - 6.4e-05 22.9 0.1 0.00018 21.5 0.1 1.7 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain KSR1-SAM PF13543.1 ETO22634.1 - 0.05 13.3 0.0 0.095 12.4 0.0 1.5 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 AKAP2_C PF15304.1 ETO22634.1 - 1.7 8.2 9.3 0.1 12.2 2.9 1.5 2 0 0 2 2 2 0 A-kinase anchor protein 2 C-terminus Gti1_Pac2 PF09729.4 ETO22634.1 - 1.7 8.4 7.6 0.34 10.7 1.4 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family RICTOR_V PF14668.1 ETO22635.1 - 0.032 14.1 0.2 0.41 10.6 0.3 2.4 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 Arm PF00514.18 ETO22635.1 - 0.52 10.2 5.8 7.5 6.5 0.2 4.3 3 1 0 3 3 3 0 Armadillo/beta-catenin-like repeat FCP1_C PF09309.5 ETO22635.1 - 0.57 9.4 20.1 0.058 12.7 3.2 2.4 2 0 0 2 2 2 0 FCP1, C-terminal DUF3987 PF13148.1 ETO22635.1 - 4.6 5.6 10.7 0.89 8.0 3.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) TPR_11 PF13414.1 ETO22636.1 - 1e-08 34.7 4.4 5.8e-08 32.2 1.2 2.5 1 1 1 2 2 2 1 TPR repeat TPR_19 PF14559.1 ETO22636.1 - 2.7e-07 30.8 1.7 0.0011 19.2 0.1 2.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO22636.1 - 3.2e-07 30.3 1.6 0.00025 21.3 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO22636.1 - 9.9e-07 29.2 1.0 0.001 19.6 0.2 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO22636.1 - 1.6e-06 27.6 7.7 2.9e-05 23.6 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO22636.1 - 9.3e-06 25.8 0.0 0.0033 17.9 0.0 3.3 3 1 1 4 4 3 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO22636.1 - 1.1e-05 25.5 15.7 0.00044 20.3 3.6 2.8 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 YfiO PF13525.1 ETO22636.1 - 3.4e-05 23.4 3.5 4.7e-05 22.9 2.4 1.2 1 0 0 1 1 1 1 Outer membrane lipoprotein TPR_18 PF13512.1 ETO22636.1 - 4.4e-05 23.5 3.2 6e-05 23.0 2.3 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO22636.1 - 8.8e-05 22.3 2.7 0.1 12.5 0.7 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO22636.1 - 9.3e-05 21.8 4.6 0.0013 18.2 0.5 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO22636.1 - 0.0015 18.1 6.5 0.0027 17.3 0.2 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO22636.1 - 0.016 15.0 1.9 0.48 10.3 0.1 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 ETO22636.1 - 0.016 15.3 0.5 0.38 11.0 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 ETO22636.1 - 0.066 13.0 0.4 0.21 11.4 0.2 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETO22637.1 - 4.1e-06 27.0 0.1 0.00012 22.3 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO22637.1 - 7.1e-05 22.3 0.9 0.036 13.7 0.1 3.6 2 1 1 3 3 3 2 TPR repeat TPR_7 PF13176.1 ETO22637.1 - 0.0027 17.3 0.1 0.097 12.5 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO22637.1 - 0.0076 16.1 0.2 0.091 12.7 0.1 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat EHN PF06441.7 ETO22637.1 - 0.098 12.5 2.2 0.29 11.0 1.5 1.8 1 0 0 1 1 1 0 Epoxide hydrolase N terminus TPR_1 PF00515.23 ETO22637.1 - 0.32 10.6 4.5 0.42 10.3 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat EURL PF06937.6 ETO22638.1 - 0.029 13.7 6.5 0.045 13.1 4.5 1.3 1 0 0 1 1 1 0 EURL protein RNA_pol_3_Rpc31 PF11705.3 ETO22639.1 - 0.14 12.0 4.7 0.24 11.3 3.3 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2207 PF09972.4 ETO22640.1 - 0.16 10.5 5.9 0.38 9.2 4.1 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) 2TM PF13239.1 ETO22640.1 - 3.2 7.8 11.0 5.5 7.1 5.7 2.6 2 0 0 2 2 2 0 2TM domain MitMem_reg PF13012.1 ETO22641.1 - 1.7e-22 79.6 4.1 1.1e-21 77.0 2.8 2.2 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 ETO22641.1 - 2e-05 24.2 0.0 2e-05 24.2 0.0 2.6 2 1 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF2201_N PF13203.1 ETO22641.1 - 0.0098 15.0 5.2 0.014 14.5 3.6 1.2 1 0 0 1 1 1 1 Putative metallopeptidase domain Mem_trans PF03547.13 ETO22641.1 - 0.1 10.9 0.0 0.12 10.6 0.0 1.2 1 0 0 1 1 1 0 Membrane transport protein CDC45 PF02724.9 ETO22641.1 - 0.47 8.4 13.6 0.57 8.1 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein GAGA_bind PF06217.7 ETO22641.1 - 3.7 7.4 12.1 5.1 6.9 8.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF1510 PF07423.6 ETO22641.1 - 5 6.4 28.8 9.2 5.5 20.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1510) Aminotran_1_2 PF00155.16 ETO22642.1 - 1.5e-58 198.5 0.0 1.5e-54 185.3 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Myb_DNA-binding PF00249.26 ETO22642.1 - 0.0025 17.8 0.4 3.8 7.6 0.0 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain EF-hand_4 PF12763.2 ETO22643.1 - 0.044 13.5 0.4 0.06 13.0 0.3 1.3 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand TAXi_N PF14543.1 ETO22644.1 - 0.018 14.9 0.6 0.035 14.0 0.3 1.4 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal Toxin_17 PF08086.6 ETO22644.1 - 0.1 12.6 1.4 0.2 11.7 0.2 2.0 2 0 0 2 2 2 0 Ergtoxin family Peptidase_C78 PF07910.8 ETO22645.1 - 7.9e-09 34.9 0.5 2.6e-05 23.4 0.0 2.4 2 1 0 2 2 2 2 Peptidase family C78 Peptidase_C54 PF03416.14 ETO22645.1 - 0.031 13.4 1.1 0.13 11.3 0.0 1.8 1 1 1 2 2 2 0 Peptidase family C54 Synaptobrevin PF00957.16 ETO22646.1 - 7.6e-14 51.0 2.2 7.6e-14 51.0 1.5 1.7 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.1 ETO22646.1 - 1.2e-07 31.2 0.0 2.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Rsd_AlgQ PF04353.8 ETO22646.1 - 0.014 15.0 0.2 0.027 14.2 0.1 1.4 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ COG2 PF06148.6 ETO22646.1 - 0.021 14.6 1.2 0.021 14.6 0.8 1.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DASH_Dad1 PF08649.5 ETO22646.1 - 0.04 13.6 0.6 0.085 12.5 0.4 1.6 1 0 0 1 1 1 0 DASH complex subunit Dad1 NusB PF01029.13 ETO22646.1 - 0.09 12.7 1.1 0.16 11.9 0.4 1.6 1 1 0 2 2 2 0 NusB family MtrB PF05440.7 ETO22646.1 - 0.12 12.4 0.7 0.35 10.9 0.3 1.8 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B I_LWEQ PF01608.12 ETO22646.1 - 0.31 10.9 2.3 0.44 10.4 0.2 2.0 2 0 0 2 2 2 0 I/LWEQ domain Sec20 PF03908.8 ETO22646.1 - 0.33 10.6 3.6 0.2 11.3 0.6 1.9 2 0 0 2 2 2 0 Sec20 DUF1664 PF07889.7 ETO22646.1 - 0.47 10.2 4.5 0.14 11.9 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Mt_ATP-synt_B PF05405.9 ETO22646.1 - 0.63 9.4 5.9 0.94 8.9 1.1 2.2 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF2508 PF10704.4 ETO22646.1 - 5.8 7.1 6.7 4.5 7.5 0.8 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2508) Thioredoxin PF00085.15 ETO22648.1 - 1.2e-06 28.1 1.7 1.3e-06 28.0 0.2 1.7 2 0 0 2 2 2 1 Thioredoxin TraF PF13728.1 ETO22648.1 - 1.7e-05 24.4 0.5 5e-05 22.8 0.1 1.9 1 1 0 1 1 1 1 F plasmid transfer operon protein Inhibitor_I24 PF10465.4 ETO22648.1 - 0.0015 18.2 0.1 0.018 14.7 0.0 2.1 1 1 0 2 2 2 1 PinA peptidase inhibitor Thioredoxin_2 PF13098.1 ETO22648.1 - 0.068 13.3 3.3 1.5 9.0 2.3 3.0 1 1 0 1 1 1 0 Thioredoxin-like domain YejG PF13989.1 ETO22648.1 - 0.077 13.0 2.6 0.1 12.6 0.1 2.1 2 0 0 2 2 2 0 YejG-like protein YgaB PF14182.1 ETO22648.1 - 1.4 9.2 12.0 0.72 10.1 2.0 3.3 2 1 1 3 3 3 0 YgaB-like protein Sod_Fe_C PF02777.13 ETO22649.1 - 9.3e-40 134.7 1.5 1.4e-39 134.1 1.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 ETO22649.1 - 3.5e-14 52.8 0.4 7.8e-14 51.7 0.3 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain NDUF_B6 PF09782.4 ETO22649.1 - 0.1 12.4 0.8 0.23 11.3 0.5 1.7 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit Tubulin_3 PF14881.1 ETO22650.1 - 5.6e-07 29.1 0.1 1.8e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 Tubulin domain DUF946 PF06101.6 ETO22651.1 - 1.7e-07 29.6 0.0 2.5e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) Pex24p PF06398.6 ETO22651.1 - 2.1e-07 30.0 12.4 2.7e-07 29.7 8.6 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Paramyx_P_V_C PF03210.8 ETO22651.1 - 0.013 15.3 0.0 0.029 14.2 0.0 1.5 1 1 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal DUF1798 PF08807.5 ETO22654.1 - 1.4 8.6 12.1 0.014 15.1 2.3 2.2 3 0 0 3 3 3 0 Bacterial domain of unknown function (DUF1798) RabGAP-TBC PF00566.13 ETO22655.1 - 2.4e-26 92.5 0.4 2.4e-26 92.5 0.3 2.6 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Orthoreo_P17 PF07272.6 ETO22656.1 - 0.017 14.9 0.3 4.4 7.0 0.3 2.2 2 1 0 2 2 2 0 Orthoreovirus P17 protein Fibrillarin PF01269.12 ETO22656.1 - 0.035 13.0 0.7 0.041 12.8 0.5 1.1 1 0 0 1 1 1 0 Fibrillarin Stork_head PF10264.4 ETO22656.1 - 0.047 13.8 0.1 0.1 12.7 0.1 1.6 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain BsuBI_PstI_RE PF06616.6 ETO22656.1 - 0.097 11.4 0.2 0.15 10.8 0.1 1.2 1 1 0 1 1 1 0 BsuBI/PstI restriction endonuclease C-terminus PAN_4 PF14295.1 ETO22657.1 - 0.0049 16.5 0.1 0.011 15.4 0.1 1.6 1 1 0 1 1 1 1 PAN domain PAN_1 PF00024.21 ETO22657.1 - 0.0062 16.2 1.6 0.012 15.4 1.1 1.5 1 1 0 1 1 1 1 PAN domain DUF3439 PF11921.3 ETO22657.1 - 9.6 5.9 8.9 22 4.8 6.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Ank_2 PF12796.2 ETO22658.1 - 5e-15 55.6 0.1 3.3e-08 33.7 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO22658.1 - 1.8e-07 31.1 0.0 0.0053 16.9 0.0 2.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO22658.1 - 2.6e-07 30.9 0.1 0.00048 20.5 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 ETO22658.1 - 3.8e-06 26.4 0.2 0.02 14.6 0.0 2.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 ETO22658.1 - 6.8e-06 25.8 0.7 0.071 13.3 0.0 3.6 4 1 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 ETO22659.1 - 2.7e-30 104.5 2.2 3.9e-19 68.7 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETO22659.1 - 3.7e-21 73.8 0.1 3.1e-06 26.7 0.1 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 ETO22659.1 - 4.8e-16 58.7 0.1 3e-07 30.7 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO22659.1 - 3.8e-15 54.4 0.1 0.0019 18.2 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 ETO22659.1 - 3.9e-15 55.5 0.8 4.1e-05 23.6 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Complex1_LYR_1 PF13232.1 ETO22660.1 - 0.12 12.6 0.2 1.3 9.3 0.1 2.2 2 0 0 2 2 2 0 Complex1_LYR-like Complex1_LYR PF05347.10 ETO22660.1 - 0.14 12.0 0.0 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Complex 1 protein (LYR family) WD40 PF00400.27 ETO22661.1 - 4.4e-65 213.3 13.1 9.3e-13 47.5 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO22661.1 - 9.5e-11 41.7 0.4 1.6e-06 28.0 0.1 2.7 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO22661.1 - 2.2e-07 29.4 2.9 0.015 13.4 0.1 3.3 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO22661.1 - 1.5e-05 23.9 9.3 0.36 9.5 0.3 4.7 1 1 3 4 4 4 3 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO22661.1 - 0.00037 18.9 0.6 0.024 12.9 0.1 3.0 1 1 3 4 4 4 2 Cytochrome D1 heme domain Hira PF07569.6 ETO22661.1 - 0.011 15.0 1.0 4.8 6.3 0.0 3.6 3 2 1 4 4 4 0 TUP1-like enhancer of split DUF1652 PF07865.6 ETO22661.1 - 0.024 14.2 0.0 8 6.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1652) Nbas_N PF15492.1 ETO22661.1 - 0.034 13.2 1.5 2.4 7.1 0.0 3.3 1 1 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 ETO22661.1 - 0.17 11.5 5.2 26 4.6 0.0 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat BTB_2 PF02214.17 ETO22663.1 - 0.00028 21.0 0.1 0.38 10.9 0.0 3.0 1 1 0 1 1 1 1 BTB/POZ domain Pkinase PF00069.20 ETO22664.1 - 1.3e-63 214.5 1.0 1.6e-63 214.3 0.7 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO22664.1 - 5e-37 127.3 1.0 6.2e-37 127.0 0.7 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO22664.1 - 1.6e-08 33.8 0.1 3.7e-08 32.7 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETO22664.1 - 6.9e-08 31.7 0.0 9.7e-08 31.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 ETO22664.1 - 0.00016 21.0 0.1 0.0014 18.0 0.0 2.1 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 ETO22664.1 - 0.0016 17.7 1.1 0.021 14.1 0.1 2.2 2 0 0 2 2 2 1 RIO1 family DUF3155 PF11352.3 ETO22664.1 - 0.029 14.5 0.2 0.081 13.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3155) SRP-alpha_N PF04086.8 ETO22665.1 - 0.00061 19.2 21.1 0.00069 19.0 14.6 1.0 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal DUF3439 PF11921.3 ETO22666.1 - 1.1 9.0 6.8 0.095 12.4 1.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) WD40 PF00400.27 ETO22667.1 - 8.4e-161 516.8 43.8 8e-12 44.5 0.4 16.4 16 0 0 16 16 16 16 WD domain, G-beta repeat NACHT PF05729.7 ETO22667.1 - 2.7e-09 36.8 0.0 4.9e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Pentapeptide PF00805.17 ETO22667.1 - 2.4e-06 26.6 1.0 5.3e-06 25.5 0.7 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO22667.1 - 8.1e-05 22.3 0.3 0.00023 20.9 0.2 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA_18 PF13238.1 ETO22667.1 - 0.0016 18.7 3.6 0.0025 18.1 0.0 3.2 2 0 0 2 2 2 1 AAA domain Pentapeptide_3 PF13576.1 ETO22667.1 - 0.0023 17.8 0.6 0.0023 17.8 0.4 2.2 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) AAA_22 PF13401.1 ETO22667.1 - 0.0057 16.8 0.0 0.022 14.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain UPRTase PF14681.1 ETO22668.1 - 7.6e-06 25.2 0.0 1.5e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PHTB1_N PF14727.1 ETO22669.1 - 0.067 12.1 0.0 0.079 11.9 0.0 1.1 1 0 0 1 1 1 0 PTHB1 N-terminus RabGAP-TBC PF00566.13 ETO22670.1 - 1.5e-08 34.4 2.5 6.8e-08 32.2 1.7 2.4 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF1168 PF06658.7 ETO22671.1 - 1.3e-19 70.0 20.9 2.2e-19 69.3 14.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DUF3403 PF11883.3 ETO22671.1 - 0.058 13.6 0.5 0.58 10.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3403) GAGA_bind PF06217.7 ETO22671.1 - 2.6 7.9 17.4 6.6 6.6 12.0 1.6 1 1 0 1 1 1 0 GAGA binding protein-like family U1snRNP70_N PF12220.3 ETO22672.1 - 0.07 13.4 16.9 0.14 12.4 7.2 2.1 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF3537 PF12056.3 ETO22672.1 - 0.078 11.6 1.4 0.095 11.3 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) Prothymosin PF03247.9 ETO22672.1 - 0.26 11.4 17.9 3.5 7.8 8.6 2.0 2 0 0 2 2 2 0 Prothymosin/parathymosin family DUF4551 PF15087.1 ETO22672.1 - 0.93 7.7 12.1 1.1 7.4 8.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CDC45 PF02724.9 ETO22672.1 - 2.1 6.2 10.8 2.6 5.9 7.5 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.7 ETO22672.1 - 3.1 6.4 7.0 3.7 6.2 4.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Nop14 PF04147.7 ETO22673.1 - 0.26 9.1 32.0 0.34 8.7 22.2 1.3 1 0 0 1 1 1 0 Nop14-like family Utp14 PF04615.8 ETO22673.1 - 0.39 8.8 26.9 0.45 8.6 18.7 1.0 1 0 0 1 1 1 0 Utp14 protein Atrophin-1 PF03154.10 ETO22673.1 - 5.5 4.9 11.0 6.9 4.6 7.7 1.2 1 0 0 1 1 1 0 Atrophin-1 family HEAT PF02985.17 ETO22674.1 - 0.009 16.0 1.8 2.5 8.3 0.2 2.7 2 0 0 2 2 2 2 HEAT repeat ETRAMP PF09716.5 ETO22674.1 - 0.013 15.3 0.0 3.4 7.6 0.0 3.0 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) YMF19 PF02326.10 ETO22674.1 - 3.9 8.1 11.0 0.2 12.2 1.1 3.2 3 0 0 3 3 3 0 Plant ATP synthase F0 Herpes_DNAp_acc PF04929.7 ETO22675.1 - 1.8 7.4 11.2 2.2 7.1 7.7 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Myb_DNA-binding PF00249.26 ETO22676.1 - 9.5e-07 28.7 0.0 1.8e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 ETO22676.1 - 0.0077 16.3 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain PIN_3 PF13470.1 ETO22676.1 - 0.069 13.8 0.0 0.1 13.2 0.0 1.3 1 0 0 1 1 1 0 PIN domain Voltage_CLC PF00654.15 ETO22677.1 - 0.082 11.9 4.0 0.2 10.6 0.0 2.0 1 1 1 2 2 2 0 Voltage gated chloride channel Apo-CII PF05355.6 ETO22679.1 - 0.027 14.3 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 Apolipoprotein C-II Pox_Ag35 PF03286.9 ETO22679.1 - 0.04 13.4 1.9 0.059 12.8 1.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Sdh_cyt PF01127.17 ETO22681.1 - 0.46 10.3 9.5 1.2 8.9 0.7 2.6 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Oxidored_q5_N PF01059.12 ETO22681.1 - 7.2 6.5 22.3 0.027 14.3 3.2 3.4 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus LRR_4 PF12799.2 ETO22682.1 - 9.1e-56 184.7 111.6 4.6e-10 38.8 1.2 16.2 10 6 10 20 20 20 15 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO22682.1 - 2.2e-34 116.9 90.4 1.5e-06 27.8 1.6 11.5 5 3 7 13 13 13 13 Leucine rich repeat LRR_9 PF14580.1 ETO22682.1 - 3.6e-18 65.7 32.7 8.6e-07 28.6 2.8 7.4 3 2 4 7 7 7 6 Leucine-rich repeat LRR_1 PF00560.28 ETO22682.1 - 3.2e-06 26.4 93.0 0.18 11.9 0.0 20.7 22 1 0 22 22 22 4 Leucine Rich Repeat LRR_6 PF13516.1 ETO22682.1 - 2e-05 24.1 88.5 0.27 11.4 0.1 19.1 15 4 3 18 18 18 7 Leucine Rich repeat LRR_7 PF13504.1 ETO22682.1 - 0.012 15.6 64.4 2.4 8.7 0.1 17.0 19 0 0 19 19 19 0 Leucine rich repeat HSP70 PF00012.15 ETO22684.1 - 9.4e-21 73.3 2.8 7e-13 47.3 0.0 2.9 1 1 2 3 3 3 2 Hsp70 protein WD40 PF00400.27 ETO22686.1 - 2e-79 258.8 20.7 7.8e-13 47.7 0.1 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO22686.1 - 8e-06 25.8 2.0 0.00047 20.2 0.1 4.1 3 1 0 3 3 3 1 Kelch motif PD40 PF07676.7 ETO22686.1 - 0.0001 21.8 6.2 3.1 7.5 0.1 6.4 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO22686.1 - 0.0033 17.6 0.4 1.2e+02 3.0 0.0 5.2 3 1 2 5 5 5 0 Resistin Kelch_5 PF13854.1 ETO22686.1 - 0.0063 16.4 0.2 0.029 14.3 0.1 2.2 1 0 0 1 1 1 1 Kelch motif Ribosomal_L33 PF00471.15 ETO22686.1 - 0.042 14.0 0.2 0.042 14.0 0.1 2.5 2 0 0 2 2 2 0 Ribosomal protein L33 Kelch_1 PF01344.20 ETO22686.1 - 1.4 8.5 6.2 0.82 9.2 0.4 3.0 2 1 0 2 2 2 0 Kelch motif Rootletin PF15035.1 ETO22687.1 - 0.0034 17.3 4.9 0.0034 17.3 3.4 5.4 5 1 1 6 6 6 2 Ciliary rootlet component, centrosome cohesion Med15_fungi PF05397.7 ETO22689.1 - 0.047 13.6 0.5 0.084 12.8 0.1 1.5 2 0 0 2 2 2 0 Mediator complex subunit 15 Ribosomal_S3Ae PF01015.13 ETO22689.1 - 0.088 12.1 0.5 0.13 11.5 0.4 1.2 1 0 0 1 1 1 0 Ribosomal S3Ae family Sel1 PF08238.7 ETO22690.1 - 0.00011 22.7 3.8 0.096 13.3 0.0 3.6 3 1 1 4 4 4 2 Sel1 repeat eIF-3c_N PF05470.7 ETO22691.1 - 0.0067 14.5 5.1 0.034 12.2 3.5 1.9 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PH PF00169.24 ETO22691.1 - 0.059 13.5 1.4 0.42 10.8 0.0 2.6 2 1 0 2 2 2 0 PH domain Daxx PF03344.10 ETO22691.1 - 7.1 4.9 37.9 0.87 7.9 22.8 1.7 2 0 0 2 2 2 0 Daxx Family RPEL PF02755.10 ETO22692.1 - 1.3e-09 37.0 4.7 0.02 14.2 0.1 6.9 7 0 0 7 7 7 3 RPEL repeat Thioredoxin_3 PF13192.1 ETO22692.1 - 0.02 14.6 3.4 59 3.5 0.0 5.3 4 1 2 6 6 6 0 Thioredoxin domain CENP-B_dimeris PF09026.5 ETO22693.1 - 0.19 11.9 3.4 27 5.0 0.0 3.5 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Chordopox_L2 PF05803.7 ETO22693.1 - 0.35 10.5 3.2 1.3 8.6 1.8 2.3 2 0 0 2 2 2 0 Chordopoxvirus L2 protein CortBP2 PF09727.4 ETO22694.1 - 0.17 11.3 0.1 0.17 11.3 0.1 1.9 2 0 0 2 2 2 0 Cortactin-binding protein-2 dDENN PF03455.14 ETO22696.1 - 0.34 11.0 3.5 13 5.8 0.0 2.6 3 0 0 3 3 3 0 dDENN domain RRM_6 PF14259.1 ETO22697.1 - 1.1e-16 60.5 0.2 3.3e-09 36.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO22697.1 - 1e-14 53.8 0.1 3.2e-06 26.6 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO22697.1 - 7.4e-09 35.3 0.4 1.6e-07 31.0 0.1 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Daxx PF03344.10 ETO22698.1 - 0.00091 17.8 6.4 0.00091 17.8 4.4 1.2 1 0 0 1 1 1 1 Daxx Family Nop14 PF04147.7 ETO22698.1 - 0.005 14.8 13.8 0.0069 14.3 9.6 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 ETO22698.1 - 0.032 12.2 7.4 0.047 11.7 5.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Menin PF05053.8 ETO22698.1 - 1 7.4 5.7 1.3 7.0 3.9 1.2 1 0 0 1 1 1 0 Menin Cwf_Cwc_15 PF04889.7 ETO22698.1 - 1.2 8.7 20.6 2.3 7.8 14.3 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Kei1 PF08552.6 ETO22699.1 - 7.1 6.2 5.9 0.77 9.3 0.8 1.7 1 1 1 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 MRG PF05712.8 ETO22700.1 - 9.4e-10 37.7 1.4 1e-09 37.5 0.1 1.6 2 0 0 2 2 2 1 MRG Tudor-knot PF11717.3 ETO22700.1 - 5.8e-07 29.1 3.2 2.4e-06 27.1 1.2 2.5 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain DUF760 PF05542.6 ETO22700.1 - 0.025 14.7 0.0 3.8 7.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF760) ATP11 PF06644.6 ETO22700.1 - 1.4 8.3 9.1 4.7 6.6 6.2 1.8 1 1 0 1 1 1 0 ATP11 protein 4HBT PF03061.17 ETO22701.1 - 0.00034 20.6 0.2 0.51 10.4 0.0 3.0 3 1 0 3 3 3 2 Thioesterase superfamily IcmL PF11393.3 ETO22701.1 - 0.039 13.8 0.2 0.091 12.7 0.1 1.6 1 0 0 1 1 1 0 Macrophage killing protein with similarity to conjugation protein Kinesin PF00225.18 ETO22702.1 - 9e-24 83.7 0.0 1.4e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Saccharop_dh_N PF04455.7 ETO22702.1 - 0.027 14.5 0.0 0.049 13.7 0.0 1.3 1 0 0 1 1 1 0 LOR/SDH bifunctional enzyme conserved region T2SE PF00437.15 ETO22702.1 - 0.15 10.9 0.0 0.22 10.3 0.0 1.3 1 1 0 1 1 1 0 Type II/IV secretion system protein zf-DHHC PF01529.15 ETO22703.1 - 0.037 13.4 3.1 3.2 7.1 0.2 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF4131 PF13567.1 ETO22703.1 - 0.25 10.7 1.7 18 4.6 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DUF788 PF05620.6 ETO22703.1 - 0.25 11.1 2.7 5.6 6.7 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF788) P12 PF12669.2 ETO22703.1 - 2.2 8.5 5.2 1.4 9.1 0.1 2.3 2 0 0 2 2 2 0 Virus attachment protein p12 family T4_deiodinase PF00837.12 ETO22704.1 - 3.9e-16 58.8 0.0 5.6e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Iodothyronine deiodinase DUF2457 PF10446.4 ETO22704.1 - 0.094 11.4 2.9 0.13 10.9 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Otopetrin PF03189.8 ETO22705.1 - 0.95 8.3 7.5 0.15 11.0 1.8 2.0 2 0 0 2 2 2 0 Otopetrin TraV PF09676.5 ETO22705.1 - 4.6 7.9 16.7 1.4 9.5 4.6 3.1 3 0 0 3 3 3 0 Type IV conjugative transfer system lipoprotein (TraV) Spt5_N PF11942.3 ETO22705.1 - 7.8 7.1 27.7 7.1 7.3 10.8 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Ribosomal_S26e PF01283.14 ETO22707.1 - 1.3e-35 122.0 9.9 3.4e-35 120.7 6.9 1.7 1 1 0 1 1 1 1 Ribosomal protein S26e Interfer-bind PF09294.5 ETO22707.1 - 0.22 11.5 3.4 0.22 11.5 0.1 2.2 1 1 1 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III DUF1620 PF07774.8 ETO22708.1 - 9e-41 139.5 1.0 1.6e-22 79.8 0.2 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 ETO22708.1 - 0.068 12.6 0.0 0.29 10.5 0.0 2.0 2 0 0 2 2 2 0 PQQ-like domain Kinase-like PF14531.1 ETO22709.1 - 0.0032 16.4 0.0 0.0061 15.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like DUF2413 PF10310.4 ETO22710.1 - 0.0023 16.8 0.3 0.0027 16.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) DNA_ligase_A_N PF04675.9 ETO22710.1 - 0.047 13.5 0.2 0.055 13.2 0.1 1.2 1 0 0 1 1 1 0 DNA ligase N terminus Raftlin PF15250.1 ETO22711.1 - 0.0066 15.0 0.4 0.0066 15.0 0.3 1.1 1 0 0 1 1 1 1 Raftlin Vfa1 PF08432.5 ETO22711.1 - 0.0073 16.3 4.2 0.011 15.7 2.9 1.4 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 RXT2_N PF08595.6 ETO22711.1 - 0.021 14.6 2.5 0.035 13.8 1.7 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal POX PF07526.6 ETO22711.1 - 0.054 13.7 2.6 0.12 12.5 1.8 1.6 1 0 0 1 1 1 0 Associated with HOX FAM176 PF14851.1 ETO22711.1 - 0.085 12.5 2.4 0.15 11.7 1.7 1.3 1 0 0 1 1 1 0 FAM176 family TPR_11 PF13414.1 ETO22712.1 - 8.4e-14 50.9 2.2 7e-07 28.7 0.2 3.3 2 1 2 4 4 4 3 TPR repeat TPR_1 PF00515.23 ETO22712.1 - 1.3e-12 46.7 6.0 4.4e-06 26.0 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO22712.1 - 2.5e-09 36.3 1.6 0.0028 17.4 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 ETO22712.1 - 3.2e-06 26.8 0.1 0.0081 15.9 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO22712.1 - 0.00039 20.0 2.9 0.0045 16.6 0.1 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO22712.1 - 0.0016 18.3 0.3 0.035 14.0 0.1 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO22712.1 - 0.18 12.0 1.8 32 5.0 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat AtpR PF12966.2 ETO22713.1 - 2.8 8.1 5.8 3.9 7.6 0.1 2.6 2 1 1 3 3 3 0 N-ATPase, AtpR subunit DUF1563 PF07599.6 ETO22714.1 - 0.034 14.0 0.1 0.079 12.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) TIM21 PF08294.6 ETO22714.1 - 0.046 13.3 0.2 0.22 11.1 0.0 2.1 2 0 0 2 2 2 0 TIM21 Calici_coat_C PF08435.6 ETO22717.1 - 0.25 10.6 3.0 0.21 10.8 0.5 1.9 2 0 0 2 2 2 0 Calicivirus coat protein C-terminal zf-H2C2_2 PF13465.1 ETO22718.1 - 8.9e-07 28.9 14.7 2.3e-05 24.4 0.7 3.4 3 0 0 3 3 3 2 Zinc-finger double domain SR-25 PF10500.4 ETO22718.1 - 0.0057 16.1 5.8 0.0088 15.5 4.0 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein zf-C2H2_4 PF13894.1 ETO22718.1 - 0.013 15.8 10.8 0.26 11.7 0.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4613 PF15390.1 ETO22718.1 - 0.014 13.6 0.5 0.015 13.4 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Dsh_C PF12316.3 ETO22718.1 - 0.019 15.1 5.4 0.021 14.9 3.7 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF4614 PF15391.1 ETO22718.1 - 0.019 14.7 3.2 0.025 14.3 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Tmemb_cc2 PF10267.4 ETO22718.1 - 0.03 12.9 3.7 0.036 12.6 2.5 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein zf-BED PF02892.10 ETO22718.1 - 0.032 14.0 19.8 0.043 13.5 2.7 3.0 2 2 1 3 3 3 0 BED zinc finger Secretin_N_2 PF07655.8 ETO22718.1 - 0.094 13.1 10.4 0.14 12.5 7.2 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain zf-C2H2_jaz PF12171.3 ETO22718.1 - 0.17 12.0 0.3 0.17 12.0 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 ETO22718.1 - 0.23 11.8 12.4 0.96 9.9 0.7 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type C1_1 PF00130.17 ETO22718.1 - 0.65 9.7 9.0 0.41 10.3 1.1 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CAF-1_p150 PF11600.3 ETO22718.1 - 1 8.7 7.7 1.3 8.3 5.4 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PHD PF00628.24 ETO22718.1 - 1.5 8.5 7.1 1.1 9.0 0.8 1.8 1 1 1 2 2 2 0 PHD-finger Exo_endo_phos PF03372.18 ETO22719.1 - 3.9e-05 23.6 0.0 0.00014 21.8 0.0 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DUF769 PF05590.6 ETO22719.1 - 0.056 12.6 0.0 0.079 12.1 0.0 1.3 1 0 0 1 1 1 0 Xylella fastidiosa protein of unknown function (DUF769) DNA_pack_C PF02499.10 ETO22719.1 - 0.11 11.1 0.2 0.16 10.6 0.1 1.1 1 0 0 1 1 1 0 Probable DNA packing protein, C-terminus zf-C5HC2 PF02928.11 ETO22720.1 - 4.9e-09 36.1 11.9 4.9e-09 36.1 8.3 1.8 2 0 0 2 2 2 1 C5HC2 zinc finger ARID PF01388.16 ETO22721.1 - 1.1e-08 34.8 2.4 1.2e-07 31.4 1.6 2.3 1 1 0 1 1 1 1 ARID/BRIGHT DNA binding domain C1_1 PF00130.17 ETO22721.1 - 7.1e-05 22.4 1.2 7.1e-05 22.4 0.9 3.3 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 ETO22721.1 - 0.00043 19.9 10.0 0.002 17.7 6.9 2.2 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 PHD PF00628.24 ETO22721.1 - 0.0012 18.5 8.6 0.0012 18.5 6.0 2.8 3 0 0 3 3 3 1 PHD-finger PHD_2 PF13831.1 ETO22721.1 - 0.061 12.6 8.4 1.8 7.9 2.8 3.3 2 0 0 2 2 2 0 PHD-finger RGS PF00615.14 ETO22722.1 - 0.00082 19.4 5.3 0.0023 18.0 2.4 2.3 1 1 0 1 1 1 1 Regulator of G protein signaling domain Coprogen_oxidas PF01218.13 ETO22722.1 - 0.066 11.7 0.6 0.1 11.1 0.4 1.3 1 0 0 1 1 1 0 Coproporphyrinogen III oxidase DUF2004 PF09406.5 ETO22722.1 - 0.66 10.0 4.7 0.57 10.2 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2004) MIP-T3 PF10243.4 ETO22723.1 - 0.00032 19.3 15.4 0.00038 19.0 10.7 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Daxx PF03344.10 ETO22723.1 - 0.15 10.5 19.4 0.19 10.1 13.5 1.0 1 0 0 1 1 1 0 Daxx Family DUF3886 PF13025.1 ETO22724.1 - 0.068 13.1 7.9 0.14 12.1 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) DUF2387 PF09526.5 ETO22724.1 - 0.44 10.4 2.5 0.51 10.2 0.2 2.1 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) zf-C2H2_4 PF13894.1 ETO22725.1 - 0.02 15.1 0.6 0.02 15.1 0.4 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger Metallophos PF00149.23 ETO22725.1 - 0.07 12.5 2.1 0.7 9.2 1.5 2.6 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase zf-C2H2 PF00096.21 ETO22725.1 - 0.69 10.3 7.9 0.09 13.1 0.8 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type Glycoamylase PF10091.4 ETO22726.1 - 0.0013 17.8 0.0 0.0027 16.8 0.0 1.4 1 0 0 1 1 1 1 Putative glucoamylase SprA-related PF12118.3 ETO22726.1 - 0.017 14.4 11.5 0.032 13.5 8.0 1.4 1 0 0 1 1 1 0 SprA-related family DUF4011 PF13195.1 ETO22726.1 - 1.1 9.2 10.3 2.6 8.0 7.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) Spore_coat_CotO PF14153.1 ETO22726.1 - 1.3 8.4 18.8 2.9 7.3 13.1 1.5 1 0 0 1 1 1 0 Spore coat protein CotO Nop16 PF09420.5 ETO22726.1 - 2.4 8.2 14.7 5.2 7.1 10.0 1.7 1 1 0 1 1 1 0 Ribosome biogenesis protein Nop16 CDC45 PF02724.9 ETO22726.1 - 2.9 5.8 14.1 4.3 5.2 9.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Ank PF00023.25 ETO22727.1 - 5.5e-06 25.9 0.1 9.2e-05 22.0 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 ETO22727.1 - 6.8e-06 26.3 0.0 2.4e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO22727.1 - 8.9e-05 22.3 0.0 0.0035 17.4 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 ETO22727.1 - 0.0086 16.5 0.0 0.026 15.0 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) GPCR_chapero_1 PF11904.3 ETO22728.1 - 1.6e-16 60.3 0.5 8.2e-11 41.6 0.2 2.0 1 1 1 2 2 2 2 GPCR-chaperone MRI PF15325.1 ETO22729.1 - 0.4 11.6 7.3 0.078 13.9 1.0 2.5 2 0 0 2 2 2 0 Modulator of retrovirus infection WD40 PF00400.27 ETO22730.1 - 3.9e-06 26.5 4.8 0.0013 18.5 0.2 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat YqgF PF14639.1 ETO22731.1 - 3.2e-17 62.4 0.0 9.1e-17 61.0 0.0 1.7 1 1 1 2 2 2 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.1 ETO22731.1 - 1.9e-09 37.5 0.0 3.3e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif Pep_deformylase PF01327.16 ETO22732.1 - 0.037 13.4 0.3 0.062 12.6 0.2 1.4 1 0 0 1 1 1 0 Polypeptide deformylase Dmrt1 PF12374.3 ETO22732.1 - 6.6 7.1 7.7 2.3 8.6 0.7 2.9 2 2 0 2 2 2 0 Double-sex mab3 related transcription factor 1 zf-TRAF PF02176.13 ETO22733.1 - 1.4e-06 28.5 4.3 1.4e-06 28.5 3.0 2.3 3 0 0 3 3 3 1 TRAF-type zinc finger WD40 PF00400.27 ETO22734.1 - 1.1e-64 212.1 20.0 8.6e-12 44.4 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO22734.1 - 6.9e-15 54.1 11.6 8.8e-05 20.8 0.0 6.0 3 1 3 6 6 6 4 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO22734.1 - 6.7e-05 23.1 1.5 6.7e-05 23.1 1.0 2.4 2 0 0 2 2 2 1 TRAF-type zinc finger V_ATPase_I PF01496.14 ETO22734.1 - 0.002 16.1 1.7 0.0029 15.5 1.2 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF342 PF03961.8 ETO22734.1 - 0.0025 16.3 2.8 0.0036 15.7 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF342) ADIP PF11559.3 ETO22734.1 - 0.0068 16.3 8.7 0.019 14.9 6.0 1.7 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.6 ETO22734.1 - 0.04 13.8 2.9 0.11 12.3 2.0 1.8 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) IncA PF04156.9 ETO22734.1 - 0.049 13.2 8.7 0.098 12.2 6.0 1.4 1 0 0 1 1 1 0 IncA protein DUF4446 PF14584.1 ETO22734.1 - 0.087 12.6 3.1 0.11 12.3 1.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) HAUS5 PF14817.1 ETO22734.1 - 0.097 11.2 3.2 0.13 10.7 2.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 CENP-F_leu_zip PF10473.4 ETO22734.1 - 0.78 9.5 13.0 1.6 8.6 9.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.7 ETO22734.1 - 1.1 8.9 6.9 2.3 7.9 4.8 1.5 1 0 0 1 1 1 0 Laminin Domain II COX16 PF14138.1 ETO22734.1 - 3.7 7.7 5.5 3.9 7.7 2.4 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein COX16 DivIC PF04977.10 ETO22734.1 - 4.1 6.9 8.4 0.57 9.7 0.3 2.7 1 1 1 2 2 2 0 Septum formation initiator OEP PF02321.13 ETO22734.1 - 5.8 6.4 7.8 6.7 6.2 3.5 2.0 1 1 1 2 2 2 0 Outer membrane efflux protein DUF3498 PF12004.3 ETO22734.1 - 9 5.2 10.2 14 4.7 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) WD40 PF00400.27 ETO22735.1 - 8.8e-63 206.1 15.5 1.8e-11 43.4 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO22735.1 - 7.4e-06 24.3 1.0 0.49 8.4 0.0 4.4 1 1 2 4 4 4 2 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO22735.1 - 0.00019 21.4 0.2 0.088 13.0 0.0 3.3 2 0 0 2 2 2 1 Kelch motif Nucleoporin_N PF08801.6 ETO22735.1 - 0.00084 18.1 7.0 0.045 12.4 0.1 3.7 2 2 1 3 3 3 3 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO22735.1 - 0.0041 15.4 0.7 1.8 6.8 0.0 3.3 2 1 2 4 4 4 2 Cytochrome D1 heme domain PD40 PF07676.7 ETO22735.1 - 0.03 14.0 4.8 11 5.8 0.0 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Kelch_5 PF13854.1 ETO22735.1 - 0.22 11.5 1.5 16 5.5 0.1 3.2 3 0 0 3 3 3 0 Kelch motif Resistin PF06954.6 ETO22735.1 - 0.38 11.0 3.0 17 5.7 0.0 4.3 3 2 1 4 4 4 0 Resistin KH_3 PF13014.1 ETO22737.1 - 0.02 14.5 0.3 0.34 10.6 0.1 2.6 2 0 0 2 2 2 0 KH domain Methyltransf_12 PF08242.7 ETO22738.1 - 0.021 15.3 0.0 0.033 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Sld5 PF05916.6 ETO22739.1 - 3.8e-15 56.0 0.2 5.2e-15 55.6 0.1 1.2 1 0 0 1 1 1 1 GINS complex protein Condensation PF00668.15 ETO22739.1 - 0.11 11.3 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Condensation domain Mur_ligase_M PF08245.7 ETO22740.1 - 0.0037 17.3 0.0 0.0056 16.7 0.0 1.3 1 0 0 1 1 1 1 Mur ligase middle domain Anp1 PF03452.9 ETO22741.1 - 0.033 13.3 2.5 0.037 13.1 1.7 1.0 1 0 0 1 1 1 0 Anp1 PTPS PF01242.14 ETO22742.1 - 0.049 13.3 0.3 0.21 11.2 0.2 2.1 1 1 1 2 2 2 0 6-pyruvoyl tetrahydropterin synthase zf-TRAF PF02176.13 ETO22743.1 - 4.4e-06 26.9 1.5 4.4e-06 26.9 1.0 2.9 3 0 0 3 3 3 1 TRAF-type zinc finger Mito_carr PF00153.22 ETO22745.1 - 1.1e-40 137.2 0.6 5e-16 58.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ras PF00071.17 ETO22746.1 - 4.3e-19 68.4 0.1 6.5e-19 67.8 0.1 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO22746.1 - 2.1e-05 25.0 0.0 3.9e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO22746.1 - 0.004 16.4 0.1 0.0063 15.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Pkinase PF00069.20 ETO22748.1 - 2.2e-16 59.7 0.2 2e-15 56.6 0.2 2.0 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 ETO22748.1 - 0.078 12.6 1.2 2 8.0 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF999 PF06198.6 ETO22749.1 - 2.5 7.9 5.1 4.8 6.9 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF999) Pkinase PF00069.20 ETO22751.1 - 7.9e-21 74.3 2.5 7.9e-21 74.3 1.7 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO22751.1 - 3.6e-17 62.3 0.1 6.6e-17 61.4 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO22751.1 - 0.0027 16.8 2.5 0.0044 16.1 1.5 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CENP-B_dimeris PF09026.5 ETO22751.1 - 0.006 16.7 6.3 0.006 16.7 4.4 2.7 2 1 0 2 2 1 1 Centromere protein B dimerisation domain RXT2_N PF08595.6 ETO22751.1 - 0.009 15.8 3.7 0.009 15.8 2.6 2.5 2 1 0 2 2 2 1 RXT2-like, N-terminal Spore_coat_CotO PF14153.1 ETO22751.1 - 0.055 12.8 9.3 0.26 10.6 2.0 2.3 2 0 0 2 2 2 0 Spore coat protein CotO CbtA PF09490.5 ETO22751.1 - 0.062 12.6 0.3 0.1 11.9 0.2 1.3 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) L_lactis_RepB_C PF06430.7 ETO22751.1 - 0.086 12.9 0.5 0.086 12.9 0.3 2.4 2 1 0 2 2 2 0 Lactococcus lactis RepB C-terminus Prothymosin PF03247.9 ETO22751.1 - 0.1 12.7 39.0 0.92 9.6 13.3 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family PPP4R2 PF09184.6 ETO22751.1 - 0.1 12.1 26.7 0.054 13.0 6.0 2.1 2 0 0 2 2 2 0 PPP4R2 Daxx PF03344.10 ETO22751.1 - 0.14 10.6 23.1 0.071 11.5 6.4 2.1 2 0 0 2 2 2 0 Daxx Family Nucleoplasmin PF03066.10 ETO22751.1 - 0.16 11.4 21.2 0.2 11.1 7.5 2.4 2 0 0 2 2 2 0 Nucleoplasmin Vfa1 PF08432.5 ETO22751.1 - 0.24 11.3 21.2 0.52 10.3 1.9 3.2 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 Sigma70_ner PF04546.8 ETO22751.1 - 0.26 10.8 15.8 0.083 12.4 3.2 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Afi1 PF07792.7 ETO22751.1 - 0.44 10.5 13.7 0.53 10.2 0.6 2.4 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking YL1 PF05764.8 ETO22751.1 - 0.75 9.3 21.0 0.66 9.5 3.8 2.2 2 0 0 2 2 2 0 YL1 nuclear protein GCIP PF13324.1 ETO22751.1 - 0.94 8.6 12.0 6.5 5.8 0.0 3.2 3 0 0 3 3 3 0 Grap2 and cyclin-D-interacting DUF4637 PF15470.1 ETO22751.1 - 3.4 7.2 10.6 4 7.0 1.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) DUF1510 PF07423.6 ETO22751.1 - 4.1 6.7 21.6 2.2 7.5 4.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) NOA36 PF06524.7 ETO22751.1 - 4.5 6.4 18.8 5 6.2 3.7 2.2 2 0 0 2 2 2 0 NOA36 protein FAM176 PF14851.1 ETO22751.1 - 5.2 6.7 14.4 0.65 9.6 2.6 2.4 2 0 0 2 2 2 0 FAM176 family Pox_Ag35 PF03286.9 ETO22751.1 - 5.4 6.4 18.0 0.26 10.7 1.9 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein VID27 PF08553.5 ETO22751.1 - 5.6 5.0 17.5 0.35 9.0 2.9 2.1 2 0 0 2 2 2 0 VID27 cytoplasmic protein Cwf_Cwc_15 PF04889.7 ETO22751.1 - 5.9 6.5 25.4 2.3 7.8 5.5 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.1 ETO22751.1 - 7.7 6.9 23.1 2.4 8.4 4.4 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TRAP_alpha PF03896.11 ETO22751.1 - 7.9 5.3 18.3 0.29 10.0 3.9 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Actin PF00022.14 ETO22754.1 - 3.9e-42 144.0 0.0 6.3e-23 80.8 0.0 2.9 2 1 0 2 2 2 2 Actin SLBP_RNA_bind PF15247.1 ETO22756.1 - 3.4e-15 55.5 0.8 3.4e-15 55.5 0.6 2.1 2 1 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain zf-C2H2_4 PF13894.1 ETO22756.1 - 2 8.9 7.7 8.3 7.0 5.3 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger Zn_Tnp_IS1595 PF12760.2 ETO22757.1 - 0.0031 17.2 0.4 1.6 8.5 0.1 2.9 2 0 0 2 2 2 2 Transposase zinc-ribbon domain MutS_I PF01624.15 ETO22758.1 - 0.039 13.9 0.0 0.46 10.5 0.0 2.5 1 1 0 1 1 1 0 MutS domain I MutS_V PF00488.16 ETO22759.1 - 3.8e-89 298.1 0.6 4.1e-88 294.7 0.4 2.3 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.13 ETO22759.1 - 1.5e-36 126.1 8.8 3.8e-36 124.8 1.5 3.1 2 1 0 2 2 2 2 MutS domain III MutS_IV PF05190.13 ETO22759.1 - 3.6e-07 30.2 1.2 1.4e-06 28.4 0.3 2.4 2 0 0 2 2 2 1 MutS family domain IV zf-H2C2_2 PF13465.1 ETO22760.1 - 0.0081 16.4 4.2 1.8 9.0 0.8 2.5 2 0 0 2 2 2 2 Zinc-finger double domain Tnp_zf-ribbon_2 PF13842.1 ETO22760.1 - 5 7.6 7.5 17 5.9 5.2 1.9 1 1 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon WD40 PF00400.27 ETO22761.1 - 7.5e-66 215.8 22.9 3e-12 45.9 0.2 7.0 6 1 0 6 6 6 6 WD domain, G-beta repeat DUF1258 PF06869.7 ETO22761.1 - 0.00055 19.0 3.7 0.5 9.4 0.1 3.9 2 1 2 4 4 4 2 Protein of unknown function (DUF1258) Kelch_4 PF13418.1 ETO22761.1 - 0.0076 15.9 2.1 1.7 8.4 0.0 3.6 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO22761.1 - 0.011 15.9 3.9 1.5 9.0 0.0 4.5 3 1 1 4 4 4 0 Kelch motif PQQ_2 PF13360.1 ETO22761.1 - 0.05 13.0 0.8 0.17 11.3 0.5 1.8 1 1 0 1 1 1 0 PQQ-like domain PD40 PF07676.7 ETO22761.1 - 0.16 11.7 1.1 6.9 6.4 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Kelch_1 PF01344.20 ETO22761.1 - 3.1 7.4 5.8 3.8 7.1 0.0 3.5 4 0 0 4 4 4 0 Kelch motif Neur_chan_memb PF02932.11 ETO22762.1 - 0.072 12.9 3.2 0.1 12.4 2.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Menin PF05053.8 ETO22762.1 - 0.19 9.8 7.5 0.23 9.5 5.2 1.1 1 0 0 1 1 1 0 Menin Zip PF02535.17 ETO22762.1 - 0.88 8.5 2.6 1.2 8.0 1.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter EF-hand_6 PF13405.1 ETO22764.1 - 0.066 13.1 0.0 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain NPR3 PF03666.8 ETO22765.1 - 0.0045 15.5 2.5 0.0059 15.1 1.7 1.1 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Otopetrin PF03189.8 ETO22765.1 - 0.039 12.9 0.1 0.053 12.5 0.1 1.1 1 0 0 1 1 1 0 Otopetrin DUF4168 PF13767.1 ETO22765.1 - 0.16 12.5 3.3 0.26 11.9 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4168) zf-MYND PF01753.13 ETO22765.1 - 0.41 10.5 12.4 2 8.3 2.6 2.5 2 0 0 2 2 2 0 MYND finger FAM176 PF14851.1 ETO22765.1 - 2.2 7.9 6.6 3.5 7.2 4.5 1.2 1 0 0 1 1 1 0 FAM176 family zf-DNA_Pol PF08996.5 ETO22765.1 - 7.4 5.8 11.4 0.13 11.5 1.7 2.1 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger zf-Nse PF11789.3 ETO22767.1 - 4.4e-13 48.5 0.1 8.2e-13 47.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.15 ETO22767.1 - 1.2e-05 24.6 0.4 2.7e-05 23.5 0.2 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.1 ETO22767.1 - 0.0033 17.1 0.4 0.01 15.5 0.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger S-AdoMet_synt_N PF00438.15 ETO22769.1 - 0.12 12.6 0.9 0.19 11.9 0.6 1.4 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, N-terminal domain FTCD_C PF04961.7 ETO22769.1 - 2.1 7.7 7.2 2.9 7.2 5.0 1.2 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase RNA_pol_3_Rpc31 PF11705.3 ETO22769.1 - 7.5 6.4 14.9 8.9 6.1 10.3 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PH PF00169.24 ETO22770.1 - 5.3e-09 36.2 3.1 6e-09 36.0 0.1 2.4 2 0 0 2 2 2 1 PH domain PH_8 PF15409.1 ETO22770.1 - 0.00012 22.0 0.0 0.00012 22.0 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.1 ETO22770.1 - 0.0027 17.5 1.2 0.011 15.6 0.6 2.2 1 1 0 1 1 1 1 PH domain Cauli_DNA-bind PF03310.8 ETO22770.1 - 0.023 14.5 0.1 0.057 13.2 0.0 1.7 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein Mcp5_PH PF12814.2 ETO22770.1 - 0.038 13.9 0.1 0.11 12.4 0.1 1.9 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology PH_11 PF15413.1 ETO22770.1 - 0.55 10.4 8.3 0.084 13.1 0.6 3.0 3 1 0 3 3 3 0 Pleckstrin homology domain YhhN PF07947.9 ETO22772.1 - 5.6e-17 61.7 6.1 1.1e-16 60.7 4.2 1.4 1 0 0 1 1 1 1 YhhN-like protein Glycos_transf_4 PF00953.16 ETO22772.1 - 0.16 11.7 8.4 0.4 10.4 5.8 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 4 GPS PF01825.16 ETO22773.1 - 2.7e-06 27.3 11.8 1.2e-05 25.2 8.2 2.3 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain ADH_zinc_N PF00107.21 ETO22774.1 - 2.2e-09 36.9 0.0 3e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Apis_Csd PF11671.3 ETO22775.1 - 1.4 8.7 31.5 0.032 14.0 15.4 2.3 2 0 0 2 2 2 0 Complementary sex determiner protein Thioredoxin_7 PF13899.1 ETO22776.1 - 9.1e-05 22.4 0.0 0.0003 20.7 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin-like Beta_helix PF13229.1 ETO22776.1 - 0.005 16.6 6.0 0.0076 16.0 4.1 1.2 1 0 0 1 1 1 1 Right handed beta helix region CitMHS PF03600.11 ETO22778.1 - 0.0011 17.6 0.4 0.0014 17.2 0.3 1.1 1 0 0 1 1 1 1 Citrate transporter DUF3169 PF11368.3 ETO22778.1 - 0.0066 15.6 1.9 0.074 12.2 0.9 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3169) UPF0182 PF03699.8 ETO22778.1 - 0.025 12.5 2.1 0.038 11.9 1.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF3329 PF11808.3 ETO22778.1 - 0.2 11.7 2.7 0.44 10.6 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) DUF1129 PF06570.6 ETO22778.1 - 2.9 7.1 5.6 12 5.0 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) RasGEF PF00617.14 ETO22779.1 - 4.4e-52 176.5 0.8 4.4e-52 176.5 0.6 1.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 ETO22779.1 - 0.00056 19.9 0.2 0.0016 18.4 0.2 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif DUF1944 PF09175.5 ETO22779.1 - 0.042 13.4 0.2 0.26 10.9 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1944) DUF4265 PF14085.1 ETO22779.1 - 0.049 13.3 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) WD40 PF00400.27 ETO22780.1 - 1.2e-20 72.5 9.3 1.8e-08 33.9 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO22780.1 - 0.00023 19.4 1.9 0.26 9.3 0.1 2.9 2 1 1 3 3 3 2 Nucleoporin Nup120/160 IKI3 PF04762.7 ETO22780.1 - 0.00066 17.6 0.5 0.074 10.8 0.1 2.2 1 1 1 2 2 2 2 IKI3 family Kinesin PF00225.18 ETO22781.1 - 4.8e-07 28.7 0.0 4.8e-07 28.7 0.0 2.7 2 1 0 2 2 2 1 Kinesin motor domain Peptidase_S49_N PF08496.5 ETO22781.1 - 0.052 13.3 5.4 0.31 10.8 0.2 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal p450 PF00067.17 ETO22782.1 - 0.053 12.0 2.0 0.062 11.8 1.4 1.0 1 0 0 1 1 1 0 Cytochrome P450 Amino_oxidase PF01593.19 ETO22782.1 - 0.056 12.5 0.3 0.057 12.4 0.2 1.0 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Flagellin_C PF00700.16 ETO22782.1 - 0.1 12.7 0.3 0.17 12.0 0.2 1.4 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region HALZ PF02183.13 ETO22782.1 - 0.21 11.2 8.9 0.53 10.0 6.2 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper Glyco_hydro_35 PF01301.14 ETO22783.1 - 1.1e-43 149.8 4.2 7.1e-25 88.0 0.1 3.3 3 0 0 3 3 3 2 Glycosyl hydrolases family 35 SET PF00856.23 ETO22783.1 - 1.7e-20 73.9 0.5 1.2e-19 71.1 0.1 2.4 2 1 0 2 2 2 1 SET domain Ricin_B_lectin PF00652.17 ETO22783.1 - 0.00046 20.2 0.6 0.00046 20.2 0.4 2.6 3 0 0 3 3 3 1 Ricin-type beta-trefoil lectin domain Pre-SET PF05033.11 ETO22783.1 - 0.00049 20.3 1.0 0.0017 18.5 0.7 2.0 1 0 0 1 1 1 1 Pre-SET motif Sulfate_transp PF00916.15 ETO22785.1 - 2.1e-25 89.3 0.1 4.4e-25 88.2 0.1 1.5 1 0 0 1 1 1 1 Sulfate transporter family RRN3 PF05327.6 ETO22785.1 - 0.0039 15.3 4.6 0.0051 14.9 3.2 1.3 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.9 ETO22785.1 - 0.0045 15.0 13.3 0.0056 14.7 9.2 1.2 1 0 0 1 1 1 1 CDC45-like protein Spore_coat_CotO PF14153.1 ETO22785.1 - 0.021 14.2 1.9 0.026 13.9 1.3 1.1 1 0 0 1 1 1 0 Spore coat protein CotO SAPS PF04499.10 ETO22785.1 - 0.99 7.9 3.8 1.3 7.5 2.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Tim54 PF11711.3 ETO22785.1 - 1.7 7.1 5.8 2.3 6.7 4.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Neur_chan_memb PF02932.11 ETO22786.1 - 0.53 10.1 9.0 0.071 12.9 1.8 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region zf-RING_6 PF14835.1 ETO22787.1 - 2.2e-08 33.7 5.1 2.2e-08 33.7 3.5 1.7 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.1 ETO22787.1 - 6.6e-08 32.2 12.7 9.1e-08 31.8 7.6 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 ETO22787.1 - 2.4e-07 30.2 13.7 2.4e-07 30.2 9.5 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO22787.1 - 5.2e-07 29.5 13.9 1.3e-06 28.2 9.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO22787.1 - 3.1e-06 26.7 13.0 4.9e-06 26.1 7.5 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO22787.1 - 6.4e-06 25.8 12.2 6.4e-06 25.8 8.5 2.6 4 0 0 4 4 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 ETO22787.1 - 4.3e-05 23.3 12.1 4.3e-05 23.3 8.4 2.0 3 0 0 3 3 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 ETO22787.1 - 0.00026 20.4 6.5 0.00064 19.1 4.5 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 ETO22787.1 - 0.00095 18.8 8.3 0.0017 18.0 4.3 2.5 2 1 1 3 3 3 1 RING-type zinc-finger zf-rbx1 PF12678.2 ETO22787.1 - 0.012 15.7 8.1 0.036 14.1 5.6 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger Zn_ribbon_2 PF12674.2 ETO22787.1 - 0.08 13.2 0.1 0.08 13.2 0.1 2.6 2 2 1 3 3 3 0 Putative zinc ribbon domain zf-RING_4 PF14570.1 ETO22787.1 - 0.094 12.3 12.8 0.58 9.7 9.1 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Gag_p19 PF02228.11 ETO22787.1 - 0.1 12.9 0.0 20 5.5 0.0 2.4 2 0 0 2 2 2 0 Major core protein p19 UPF0547 PF10571.4 ETO22787.1 - 0.61 9.8 0.1 0.61 9.8 0.1 3.0 4 0 0 4 4 3 0 Uncharacterised protein family UPF0547 zf-MIZ PF02891.15 ETO22787.1 - 2.4 7.7 11.1 3.7 7.1 6.5 2.2 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger DZR PF12773.2 ETO22787.1 - 5.6 6.8 10.1 34 4.3 7.0 2.4 1 1 0 1 1 1 0 Double zinc ribbon zf-H2C2_2 PF13465.1 ETO22788.1 - 5.1e-09 35.9 14.8 0.014 15.7 0.4 4.7 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 ETO22788.1 - 2.2e-07 30.7 18.3 0.015 15.5 0.5 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 ETO22788.1 - 1.1e-06 28.6 22.2 0.015 15.6 1.7 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-met PF12874.2 ETO22788.1 - 0.014 15.5 0.5 0.014 15.5 0.4 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 ETO22788.1 - 0.028 14.5 13.8 0.041 14.0 0.2 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 ETO22788.1 - 0.099 12.7 13.4 0.052 13.6 2.7 2.5 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Vps39_2 PF10367.4 ETO22788.1 - 0.12 12.5 1.5 2.4 8.3 0.3 2.4 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-C2H2_6 PF13912.1 ETO22788.1 - 2.7 8.0 10.1 1.7 8.6 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Crust_neurohorm PF01147.12 ETO22788.1 - 6.4 6.1 8.4 1.2 8.4 3.2 1.7 2 0 0 2 2 2 0 Crustacean CHH/MIH/GIH neurohormone family Hydrolase_6 PF13344.1 ETO22790.1 - 7.8e-21 73.8 0.1 5.9e-20 71.0 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ETO22790.1 - 5.5e-17 61.2 0.1 2.1e-16 59.3 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 ETO22790.1 - 1.5e-06 28.5 0.1 0.0033 17.6 0.0 2.8 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 ETO22790.1 - 0.00053 20.4 0.0 2.6 8.4 0.0 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase 7TM_GPCR_Srt PF10321.4 ETO22790.1 - 0.072 11.8 1.7 0.11 11.2 1.2 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt UDG PF03167.14 ETO22790.1 - 0.076 12.4 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 Uracil DNA glycosylase superfamily DUF342 PF03961.8 ETO22791.1 - 0.0017 16.8 6.0 0.0023 16.4 4.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF342) Mnd1 PF03962.10 ETO22791.1 - 0.018 14.6 5.6 0.33 10.5 2.1 2.3 1 1 1 2 2 2 0 Mnd1 family FlxA PF14282.1 ETO22791.1 - 0.019 14.9 8.8 0.053 13.4 1.7 2.2 2 0 0 2 2 2 0 FlxA-like protein DivIC PF04977.10 ETO22791.1 - 0.033 13.6 10.0 1.9 8.0 0.6 3.5 3 1 0 3 3 3 0 Septum formation initiator TMF_DNA_bd PF12329.3 ETO22791.1 - 0.038 13.7 0.4 0.038 13.7 0.3 4.0 3 2 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF3782 PF12644.2 ETO22791.1 - 0.11 12.2 2.0 1.1 9.0 1.4 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) Prefoldin_2 PF01920.15 ETO22791.1 - 0.21 11.3 14.0 0.63 9.8 0.1 3.4 3 1 0 3 3 3 0 Prefoldin subunit Snapin_Pallidin PF14712.1 ETO22791.1 - 0.22 11.8 6.1 0.86 9.9 0.2 2.9 2 1 1 3 3 3 0 Snapin/Pallidin Snf7 PF03357.16 ETO22791.1 - 0.41 10.0 13.4 0.18 11.1 0.2 2.6 2 1 0 2 2 2 0 Snf7 Allexi_40kDa PF05549.6 ETO22791.1 - 0.6 9.3 3.9 0.57 9.4 0.6 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein Syntaxin_2 PF14523.1 ETO22791.1 - 0.94 9.5 10.1 2.5 8.1 1.7 2.4 2 1 0 2 2 2 0 Syntaxin-like protein Seryl_tRNA_N PF02403.17 ETO22791.1 - 0.97 9.4 19.4 1.6 8.7 0.9 3.3 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF3573 PF12097.3 ETO22791.1 - 1.5 7.3 5.0 0.68 8.4 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) AAA_13 PF13166.1 ETO22791.1 - 1.5 7.1 13.5 0.24 9.8 2.2 2.3 1 1 1 2 2 2 0 AAA domain TBPIP PF07106.8 ETO22791.1 - 2.1 7.8 18.2 0.42 10.1 0.5 3.1 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Prefoldin PF02996.12 ETO22791.1 - 2.7 7.6 12.2 5.2 6.7 0.4 3.2 3 0 0 3 3 3 0 Prefoldin subunit Med9 PF07544.8 ETO22791.1 - 5.5 6.8 7.4 0.93 9.2 0.6 2.8 2 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF2203 PF09969.4 ETO22791.1 - 6.1 7.0 9.0 4.1 7.6 3.1 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Rad51 PF08423.6 ETO22792.1 - 3.9e-28 98.0 0.3 5.1e-28 97.6 0.2 1.2 1 0 0 1 1 1 1 Rad51 HHH_5 PF14520.1 ETO22792.1 - 3.5e-09 36.6 0.0 6.4e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain RecA PF00154.16 ETO22792.1 - 0.0001 21.4 0.0 0.00015 20.9 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 ETO22792.1 - 0.00053 19.1 0.3 0.00053 19.1 0.2 1.6 2 0 0 2 2 2 1 KaiC PAXNEB PF05625.6 ETO22792.1 - 0.0082 15.0 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 PAXNEB protein AAA_25 PF13481.1 ETO22792.1 - 0.014 14.8 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain HHH_3 PF12836.2 ETO22792.1 - 0.073 13.0 0.3 3.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif Orthopox_A5L PF06193.6 ETO22793.1 - 2.5e-06 27.5 0.0 7.8e-06 25.9 0.0 1.7 1 1 0 1 1 1 1 Orthopoxvirus A5L protein-like DUF3450 PF11932.3 ETO22793.1 - 0.00066 19.0 2.7 0.00066 19.0 1.9 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) IncA PF04156.9 ETO22793.1 - 0.0036 16.9 6.4 0.0036 16.9 4.4 2.7 2 1 0 2 2 2 1 IncA protein Reo_sigmaC PF04582.7 ETO22793.1 - 0.052 12.7 0.8 0.084 12.0 0.6 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Atg14 PF10186.4 ETO22793.1 - 0.078 11.9 12.8 0.23 10.3 1.5 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 CHD5 PF04420.9 ETO22793.1 - 0.12 12.0 0.1 0.12 12.0 0.1 2.2 3 0 0 3 3 3 0 CHD5-like protein Ycf1 PF05758.7 ETO22793.1 - 0.17 9.5 10.1 0.31 8.7 6.8 1.3 1 1 0 1 1 1 0 Ycf1 SOBP PF15279.1 ETO22793.1 - 0.73 10.1 10.7 0.22 11.8 5.2 1.6 2 0 0 2 2 2 0 Sine oculis-binding protein Ribosomal_S25 PF03297.10 ETO22793.1 - 0.89 9.6 5.7 2 8.5 3.9 1.5 1 0 0 1 1 1 0 S25 ribosomal protein DUF948 PF06103.6 ETO22793.1 - 3.3 7.6 5.8 0.48 10.3 0.6 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3439 PF11921.3 ETO22794.1 - 1.4 8.6 16.0 4.5 7.0 11.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3439) BTV_NS2 PF04514.7 ETO22795.1 - 0.15 10.8 14.9 0.2 10.4 10.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CAP_GLY PF01302.20 ETO22796.1 - 1.1e-09 37.8 0.2 1.9e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain SUKH_5 PF14567.1 ETO22796.1 - 0.05 13.0 0.0 0.88 9.0 0.0 2.3 2 0 0 2 2 2 0 SMI1-KNR4 cell-wall PT-HINT PF07591.6 ETO22796.1 - 0.052 13.4 0.3 0.12 12.2 0.2 1.6 1 0 0 1 1 1 0 Pretoxin HINT domain Prothymosin PF03247.9 ETO22797.1 - 7.7 6.7 44.4 0.37 10.9 14.9 3.3 3 0 0 3 3 3 0 Prothymosin/parathymosin family Kelch_4 PF13418.1 ETO22799.1 - 3.5e-08 33.0 2.3 0.01 15.5 0.0 3.9 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO22799.1 - 4.7e-06 26.0 1.0 0.0043 16.5 0.0 4.2 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.1 ETO22799.1 - 8.2e-06 25.8 1.9 0.11 12.7 0.1 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO22799.1 - 0.00015 21.7 0.0 2.7 8.2 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Xpo1 PF08389.7 ETO22800.1 - 3e-06 27.1 0.4 2.4e-05 24.2 0.0 2.3 2 1 0 2 2 2 1 Exportin 1-like protein BCL_N PF04714.8 ETO22800.1 - 0.039 13.5 0.1 6.6 6.3 0.0 2.5 2 0 0 2 2 2 0 BCL7, N-terminal conserver region Prolamin_like PF05617.6 ETO22800.1 - 0.043 13.9 0.5 0.5 10.5 0.1 2.6 2 0 0 2 2 2 0 Prolamin-like Lumazine_bd PF12870.2 ETO22800.1 - 0.19 11.7 3.3 0.37 10.8 0.0 2.6 2 1 1 3 3 3 0 Lumazine-binding domain DUF1764 PF08576.5 ETO22801.1 - 1.1 10.0 8.5 0.22 12.3 2.5 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) CAP_GLY PF01302.20 ETO22803.1 - 1e-15 57.1 0.2 1.5e-15 56.6 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain DUF2254 PF10011.4 ETO22803.1 - 0.034 12.6 0.0 0.034 12.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) DUF92 PF01940.11 ETO22803.1 - 0.12 11.5 0.1 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF92 DUF2615 PF11027.3 ETO22803.1 - 0.15 12.0 1.8 13 5.8 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) Methyltransf_12 PF08242.7 ETO22803.1 - 0.71 10.3 4.1 0.99 9.9 0.6 2.1 2 0 0 2 2 2 0 Methyltransferase domain Aldose_epim PF01263.15 ETO22804.1 - 1.1e-48 165.9 0.8 1.7e-48 165.2 0.6 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase tRNA_NucTran2_2 PF13735.1 ETO22805.1 - 0.081 12.7 1.2 0.2 11.4 0.9 1.6 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative NB PF04159.8 ETO22806.1 - 0.019 14.7 8.2 0.7 9.6 0.4 2.5 2 0 0 2 2 2 0 NB glycoprotein TFIIF_alpha PF05793.7 ETO22807.1 - 3.2e-06 25.8 38.0 3.2e-06 25.8 26.3 2.1 1 1 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2457 PF10446.4 ETO22807.1 - 0.48 9.0 30.9 0.011 14.4 15.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 ETO22807.1 - 0.59 8.1 28.9 0.014 13.4 13.1 2.0 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.7 ETO22807.1 - 6.5 4.5 36.6 0.074 10.9 18.8 2.0 2 0 0 2 2 2 0 Nop14-like family Daxx PF03344.10 ETO22807.1 - 9.6 4.5 43.7 39 2.5 29.8 1.7 1 1 1 2 2 2 0 Daxx Family Aa_trans PF01490.13 ETO22809.1 - 1.3e-06 27.2 1.3 0.00016 20.2 0.2 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein DUF1673 PF07895.6 ETO22809.1 - 4.4 6.7 7.4 10 5.6 5.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) Colicin-DNase PF12639.2 ETO22810.1 - 2.2 8.5 6.8 5.3 7.3 0.3 2.4 2 0 0 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin DUF1191 PF06697.7 ETO22811.1 - 0.0095 14.7 0.1 0.14 10.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1191) EphA2_TM PF14575.1 ETO22811.1 - 0.74 10.2 3.1 0.9 9.9 0.1 2.6 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.1 ETO22811.1 - 0.9 9.1 10.0 0.041 13.5 0.9 2.4 1 1 0 2 2 2 0 Transmembrane protein 51 Skp1 PF01466.14 ETO22812.1 - 7.3e-24 83.6 1.0 7.3e-24 83.6 0.7 1.9 2 1 0 2 2 2 1 Skp1 family, dimerisation domain DUF4469 PF14734.1 ETO22813.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4469) with IG-like fold HAD PF12710.2 ETO22814.1 - 0.03 14.4 0.3 0.038 14.1 0.2 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase YrhK PF14145.1 ETO22814.1 - 0.058 13.0 1.7 0.17 11.5 1.1 1.8 1 0 0 1 1 1 0 YrhK-like protein DUF4064 PF13273.1 ETO22814.1 - 5.9 7.0 8.1 2.5 8.2 0.4 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF4064) Scs3p PF10261.4 ETO22815.1 - 0.017 14.1 0.6 0.017 14.1 0.4 2.1 1 1 1 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM PH_10 PF15411.1 ETO22815.1 - 0.018 15.2 2.0 0.037 14.2 1.4 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Protocadherin PF08374.6 ETO22815.1 - 0.03 13.9 2.3 0.045 13.3 1.6 1.2 1 0 0 1 1 1 0 Protocadherin OAD_gamma PF04277.8 ETO22815.1 - 0.3 11.4 7.3 0.48 10.8 1.2 2.7 1 1 1 2 2 2 0 Oxaloacetate decarboxylase, gamma chain E3_UbLigase_R4 PF13764.1 ETO22815.1 - 0.37 8.6 3.1 0.55 8.0 2.1 1.1 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 BLVR PF06375.6 ETO22815.1 - 0.56 10.0 8.0 0.82 9.4 5.6 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) DUF2207 PF09972.4 ETO22815.1 - 2 6.8 19.1 0.058 11.9 3.8 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) EF-hand_8 PF13833.1 ETO22816.1 - 2.4e-06 27.0 0.1 1e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO22816.1 - 1.9e-05 23.5 0.0 6e-05 22.0 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_4 PF12763.2 ETO22816.1 - 0.00032 20.4 0.0 0.0014 18.2 0.0 2.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_6 PF13405.1 ETO22816.1 - 0.0017 18.0 0.1 0.0063 16.3 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 ETO22816.1 - 0.0057 15.9 0.0 0.0057 15.9 0.0 2.0 2 0 0 2 2 2 1 EF hand zf-C2H2 PF00096.21 ETO22817.1 - 9.2e-05 22.5 28.6 0.00086 19.5 2.2 5.0 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETO22817.1 - 0.00017 21.6 21.7 0.0097 16.1 1.9 4.4 3 1 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.7 ETO22817.1 - 0.0014 18.7 6.7 0.0014 18.7 4.7 3.6 2 1 2 4 4 4 1 Drought induced 19 protein (Di19), zinc-binding KilA-N PF04383.8 ETO22817.1 - 0.14 11.7 3.2 0.14 11.7 0.7 2.1 2 0 0 2 2 2 0 KilA-N domain zf-met2 PF12907.2 ETO22817.1 - 0.17 11.8 0.2 0.17 11.8 0.1 3.8 2 1 1 3 3 3 0 Zinc-binding ATP-synt_8 PF00895.15 ETO22817.1 - 0.6 10.3 4.3 0.29 11.3 0.3 2.5 2 0 0 2 2 2 0 ATP synthase protein 8 zf-H2C2_2 PF13465.1 ETO22817.1 - 4.4 7.7 27.0 0.22 11.8 1.2 4.7 5 0 0 5 5 5 0 Zinc-finger double domain Kelch_6 PF13964.1 ETO22818.1 - 8.7e-09 35.1 9.0 1.1e-05 25.3 0.3 4.8 4 2 2 6 6 6 3 Kelch motif Kelch_4 PF13418.1 ETO22818.1 - 0.00013 21.6 0.5 0.37 10.5 0.0 3.8 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO22818.1 - 0.058 12.9 11.3 0.66 9.5 0.7 4.2 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.10 ETO22818.1 - 0.096 12.4 8.0 13 5.7 0.0 4.6 4 1 0 4 4 4 0 Kelch motif Kelch_5 PF13854.1 ETO22818.1 - 0.12 12.3 2.8 36 4.4 0.0 3.9 4 0 0 4 4 4 0 Kelch motif zf-RING_2 PF13639.1 ETO22819.1 - 0.003 17.3 7.2 0.003 17.3 5.0 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 ETO22819.1 - 0.025 14.2 3.5 0.025 14.2 2.4 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ABC2_membrane_4 PF12730.2 ETO22819.1 - 0.062 12.4 0.3 0.093 11.8 0.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein zf-C3HC4_2 PF13923.1 ETO22819.1 - 0.37 10.8 6.5 0.1 12.6 1.5 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO22819.1 - 2 8.2 8.2 0.52 10.0 2.1 2.3 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 ETO22819.1 - 2.3 7.9 10.3 21 4.8 4.9 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Daxx PF03344.10 ETO22820.1 - 0.0013 17.3 20.3 0.0015 17.1 14.1 1.2 1 0 0 1 1 1 1 Daxx Family DUF2457 PF10446.4 ETO22820.1 - 0.03 13.0 34.9 0.054 12.2 24.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Caldesmon PF02029.10 ETO22820.1 - 0.051 11.9 16.7 0.12 10.8 11.2 1.7 2 0 0 2 2 2 0 Caldesmon SDA1 PF05285.7 ETO22820.1 - 0.26 10.5 30.6 0.35 10.1 21.2 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 ETO22820.1 - 0.73 7.6 30.8 0.92 7.3 21.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 ETO22820.1 - 1.5 6.7 23.8 1.9 6.4 16.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid PF03115.9 ETO22820.1 - 3.4 5.7 14.9 4.4 5.4 10.3 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Sulfotransfer_2 PF03567.9 ETO22822.1 - 7.3e-09 35.6 1.0 3.5e-08 33.4 0.2 2.6 2 1 0 2 2 2 1 Sulfotransferase family RRM_1 PF00076.17 ETO22824.1 - 8.1e-20 70.2 0.1 3.2e-09 36.2 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO22824.1 - 7.1e-15 54.7 0.0 1.2e-06 28.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO22824.1 - 6.6e-10 38.6 0.8 4.4e-05 23.2 0.1 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 ETO22824.1 - 0.014 15.2 0.5 0.65 9.8 0.0 2.8 2 1 1 3 3 3 0 RNA binding motif RXT2_N PF08595.6 ETO22825.1 - 0.02 14.7 2.6 0.025 14.3 1.8 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal IncA PF04156.9 ETO22825.1 - 2.2 7.8 4.4 3.4 7.2 3.0 1.3 1 0 0 1 1 1 0 IncA protein COesterase PF00135.23 ETO22826.1 - 0.008 14.9 0.8 0.0089 14.7 0.6 1.1 1 0 0 1 1 1 1 Carboxylesterase family SAM_1 PF00536.25 ETO22826.1 - 0.029 14.5 0.1 0.11 12.6 0.1 2.1 1 1 1 2 2 2 0 SAM domain (Sterile alpha motif) RGS PF00615.14 ETO22827.1 - 8.9e-07 29.0 0.5 1.7e-06 28.0 0.3 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain CDC24 PF06395.6 ETO22827.1 - 0.029 14.4 1.0 1.6 8.8 0.1 2.2 2 0 0 2 2 2 0 CDC24 Calponin DnaJ PF00226.26 ETO22828.1 - 3.1e-14 52.4 3.2 1.5e-12 47.0 0.0 2.7 2 0 0 2 2 2 2 DnaJ domain Abhydrolase_1 PF00561.15 ETO22828.1 - 0.035 13.6 0.1 0.048 13.1 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1878 PF08963.5 ETO22829.1 - 0.05 13.8 0.7 0.33 11.1 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1878) PAXIP1_C PF15364.1 ETO22829.1 - 3 7.7 9.6 0.078 12.8 1.2 2.3 2 1 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein Swi3 PF07962.7 ETO22830.1 - 6.1e-13 48.2 0.1 8.9e-13 47.6 0.1 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 EF-hand_1 PF00036.27 ETO22831.1 - 3.2e-07 29.1 1.9 0.0034 16.5 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 ETO22831.1 - 1.6e-06 28.1 1.4 7.7e-06 25.9 1.0 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO22831.1 - 3.8e-05 23.2 2.9 0.22 11.4 0.0 3.3 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 ETO22831.1 - 6.9e-05 22.0 1.8 0.0088 15.3 0.0 3.0 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 ETO22831.1 - 0.0013 18.2 0.2 0.0013 18.2 0.1 2.3 2 1 1 3 3 3 1 EF-hand domain pair SHP PF03579.8 ETO22831.1 - 0.0072 15.6 5.8 0.018 14.3 4.0 1.7 1 0 0 1 1 1 1 Small hydrophobic protein DUF912 PF06024.7 ETO22831.1 - 0.02 14.9 0.4 0.044 13.8 0.2 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3671 PF12420.3 ETO22831.1 - 0.036 14.0 4.5 0.082 12.8 3.1 1.7 1 0 0 1 1 1 0 Protein of unknown function Baculo_11_kDa PF06143.6 ETO22831.1 - 0.038 13.3 2.5 0.074 12.4 1.7 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family AsmA PF05170.9 ETO22831.1 - 0.046 12.3 0.7 0.07 11.7 0.5 1.2 1 0 0 1 1 1 0 AsmA family Shisa PF13908.1 ETO22831.1 - 0.099 12.8 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF3139 PF11337.3 ETO22831.1 - 0.24 11.7 7.2 2.8 8.2 3.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) TMEM154 PF15102.1 ETO22831.1 - 0.27 10.9 8.9 0.78 9.4 6.2 1.7 1 1 0 1 1 1 0 TMEM154 protein family Sigma_reg_N PF13800.1 ETO22831.1 - 0.55 10.3 7.6 0.52 10.3 2.3 2.5 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Herpes_LMP1 PF05297.6 ETO22831.1 - 5.5 5.8 6.4 2.8 6.7 3.0 1.4 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) tRNA_bind PF01588.15 ETO22832.1 - 1.2e-23 82.7 0.1 3.9e-22 77.8 0.1 2.2 1 1 0 1 1 1 1 Putative tRNA binding domain DSPc PF00782.15 ETO22834.1 - 1.6e-05 24.4 1.9 2.9 7.4 0.0 4.8 4 0 0 4 4 4 3 Dual specificity phosphatase, catalytic domain DUF1548 PF07579.6 ETO22834.1 - 0.021 14.9 1.1 0.021 14.9 0.8 3.3 5 0 0 5 5 5 0 Domain of Unknown Function (DUF1548) DDHD PF02862.12 ETO22834.1 - 8.8 6.0 13.3 4.8 6.9 5.4 2.7 2 1 0 2 2 2 0 DDHD domain zf-UBR PF02207.15 ETO22835.1 - 2.6e-07 30.2 9.9 4.2e-07 29.6 6.8 1.3 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) zf-B_box PF00643.19 ETO22835.1 - 0.011 15.6 2.9 0.028 14.2 2.0 1.7 1 0 0 1 1 1 0 B-box zinc finger Rhomboid PF01694.17 ETO22836.1 - 0.0038 17.2 5.4 0.01 15.8 3.8 1.6 1 0 0 1 1 1 1 Rhomboid family Popeye PF04831.8 ETO22838.1 - 6.3e-13 48.7 0.0 9.6e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.24 ETO22838.1 - 0.0086 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain MIP-T3 PF10243.4 ETO22838.1 - 0.35 9.3 50.9 0.45 8.9 35.3 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Utp14 PF04615.8 ETO22838.1 - 0.43 8.6 47.2 0.55 8.3 32.7 1.1 1 0 0 1 1 1 0 Utp14 protein TFIIA PF03153.8 ETO22838.1 - 1.3 8.8 46.1 1.9 8.3 31.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOBP PF15279.1 ETO22838.1 - 1.5 9.1 13.0 2.1 8.6 9.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein ResB PF05140.9 ETO22838.1 - 8.5 4.7 7.7 9.9 4.5 5.4 1.1 1 0 0 1 1 1 0 ResB-like family TPR_2 PF07719.12 ETO22839.1 - 3.5e-35 117.0 15.4 9.2e-07 28.3 2.6 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETO22839.1 - 4.9e-35 117.7 16.6 1.7e-08 33.6 3.5 7.3 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.1 ETO22839.1 - 7.1e-34 115.2 15.5 3e-12 46.0 2.4 5.8 4 1 2 6 6 6 6 TPR repeat TPR_16 PF13432.1 ETO22839.1 - 5.8e-21 74.6 4.8 1.5e-06 28.6 0.3 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO22839.1 - 1.5e-20 71.3 8.8 0.0024 17.5 2.7 7.1 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 ETO22839.1 - 1.4e-18 66.6 13.5 1.2e-05 25.0 1.7 6.2 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 ETO22839.1 - 2.5e-17 61.7 0.2 0.01 16.3 0.0 6.9 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO22839.1 - 3.7e-17 62.4 10.6 4.6e-05 23.6 0.2 5.9 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETO22839.1 - 5.7e-16 57.3 10.9 3.3e-05 23.7 0.3 7.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 ETO22839.1 - 9.9e-11 41.3 2.3 0.00024 20.9 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO22839.1 - 2.3e-09 37.0 9.0 0.13 12.7 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO22839.1 - 5.2e-09 35.2 5.8 4.1 7.4 0.0 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO22839.1 - 5.8e-09 35.9 28.6 4.1e-06 26.8 4.9 5.2 2 1 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 ETO22839.1 - 2.7e-07 29.9 2.4 0.049 12.6 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_20 PF14561.1 ETO22839.1 - 0.00062 19.8 2.3 0.55 10.3 0.2 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat NARP1 PF12569.3 ETO22839.1 - 0.00092 18.0 6.0 0.017 13.9 0.9 3.2 3 1 1 4 4 4 1 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.1 ETO22839.1 - 0.0098 15.7 4.0 0.055 13.3 0.1 3.7 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 ETO22839.1 - 0.016 15.1 5.0 21 5.2 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TOM20_plant PF06552.7 ETO22839.1 - 0.074 12.6 3.7 4.3 6.8 0.0 3.9 2 1 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 SHNi-TPR PF10516.4 ETO22839.1 - 0.33 10.2 5.8 0.83 8.9 0.0 3.8 5 0 0 5 5 5 0 SHNi-TPR PPTA PF01239.17 ETO22839.1 - 4.2 6.8 9.7 1.2 8.6 0.0 3.6 4 0 0 4 4 3 0 Protein prenyltransferase alpha subunit repeat TPR_11 PF13414.1 ETO22840.1 - 1.5e-09 37.3 1.6 3.1e-05 23.5 0.2 3.0 1 1 1 2 2 2 2 TPR repeat WD40 PF00400.27 ETO22840.1 - 2.6e-09 36.5 0.5 0.00057 19.6 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat TPR_1 PF00515.23 ETO22840.1 - 0.00013 21.4 12.5 0.28 10.8 0.0 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO22840.1 - 0.0025 18.1 0.6 0.84 10.0 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO22840.1 - 0.27 11.2 6.2 65 3.8 0.0 5.1 4 2 1 5 5 5 0 Tetratricopeptide repeat TIP120 PF08623.5 ETO22841.1 - 3.7e-37 127.4 4.4 2.9e-35 121.3 0.0 4.4 3 2 1 5 5 5 1 TATA-binding protein interacting (TIP20) HEAT_EZ PF13513.1 ETO22841.1 - 1.9e-15 56.8 7.3 0.53 10.8 0.0 11.9 12 3 3 15 15 15 3 HEAT-like repeat HEAT_2 PF13646.1 ETO22841.1 - 4.8e-15 55.6 10.0 6.1e-06 26.4 0.0 8.3 10 1 0 10 10 10 2 HEAT repeats HEAT PF02985.17 ETO22841.1 - 2.5e-13 48.8 19.5 0.0017 18.3 0.0 12.6 14 0 0 14 14 14 3 HEAT repeat Adaptin_N PF01602.15 ETO22841.1 - 4.8e-13 48.2 17.2 4.5e-06 25.2 0.1 5.9 3 1 1 5 5 5 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 ETO22841.1 - 8.2e-08 32.5 8.5 0.0028 18.0 0.0 8.4 8 2 4 12 12 12 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 ETO22841.1 - 1.4e-05 24.9 15.8 0.041 13.7 0.0 7.7 6 2 0 8 8 8 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 ETO22841.1 - 0.022 14.5 5.1 5.9 6.8 0.0 6.0 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat tRNA-synt_1e PF01406.14 ETO22842.1 - 3.2e-09 36.3 0.2 3.2e-09 36.3 0.1 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Bunya_RdRp PF04196.7 ETO22843.1 - 0.0078 14.2 0.4 0.0076 14.3 0.3 1.1 1 0 0 1 1 1 1 Bunyavirus RNA dependent RNA polymerase DUF1336 PF07059.7 ETO22844.1 - 4e-24 85.2 0.0 5.9e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) Apis_Csd PF11671.3 ETO22844.1 - 0.0047 16.7 5.8 0.0088 15.8 4.0 1.4 1 0 0 1 1 1 1 Complementary sex determiner protein Tim54 PF11711.3 ETO22844.1 - 0.77 8.2 4.1 0.65 8.5 0.1 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 BAF1_ABF1 PF04684.8 ETO22845.1 - 3.4 6.3 15.5 5.3 5.7 10.7 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Fez1 PF06818.10 ETO22847.1 - 0.0021 18.1 4.7 0.0021 18.1 3.3 1.7 2 0 0 2 2 2 1 Fez1 Golgin_A5 PF09787.4 ETO22847.1 - 0.0074 14.8 11.9 0.0097 14.4 8.3 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 ETRAMP PF09716.5 ETO22847.1 - 0.051 13.5 0.2 0.24 11.4 0.1 2.2 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Atg14 PF10186.4 ETO22847.1 - 0.13 11.1 7.7 0.014 14.3 2.6 1.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 GP41 PF00517.12 ETO22847.1 - 0.22 11.0 7.9 0.43 10.0 5.5 1.4 1 0 0 1 1 1 0 Retroviral envelope protein DUF4613 PF15390.1 ETO22847.1 - 0.45 8.6 7.0 0.51 8.4 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) V_ATPase_I PF01496.14 ETO22847.1 - 0.49 8.1 5.5 0.59 7.9 3.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family WXG100 PF06013.7 ETO22847.1 - 0.91 9.5 4.7 0.28 11.2 1.3 1.6 2 0 0 2 2 2 0 Proteins of 100 residues with WXG IncA PF04156.9 ETO22847.1 - 1.2 8.7 10.7 1.6 8.2 7.4 1.3 1 0 0 1 1 1 0 IncA protein Exonuc_VII_L PF02601.10 ETO22847.1 - 1.9 7.6 9.3 2.3 7.3 6.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Occludin_ELL PF07303.8 ETO22847.1 - 2.4 8.9 11.8 2.6 8.8 7.1 1.9 1 1 2 3 3 2 0 Occludin homology domain TMPIT PF07851.8 ETO22847.1 - 3.7 6.5 9.4 5.4 5.9 6.5 1.5 1 0 0 1 1 1 0 TMPIT-like protein KfrA_N PF11740.3 ETO22847.1 - 4.1 7.8 6.7 7.8 6.9 2.0 2.2 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term FlaC_arch PF05377.6 ETO22847.1 - 4.7 7.1 9.3 1.1 9.2 1.7 2.6 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF3552 PF12072.3 ETO22847.1 - 6.3 5.9 21.9 1.5 7.9 11.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Rotamase PF00639.16 ETO22847.1 - 7.6 7.3 8.6 3.5 8.4 3.0 2.3 1 1 0 2 2 2 0 PPIC-type PPIASE domain LRS4 PF10422.4 ETO22847.1 - 10 5.4 18.8 1.9 7.7 10.7 1.5 1 1 1 2 2 2 0 Monopolin complex subunit LRS4 DDHD PF02862.12 ETO22848.1 - 1.5 8.5 6.2 1.6 8.4 4.3 1.1 1 0 0 1 1 1 0 DDHD domain Vps4_C PF09336.5 ETO22849.1 - 0.059 13.2 0.2 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain Med12 PF09497.5 ETO22849.1 - 0.088 12.8 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Transcription mediator complex subunit Med12 RHH_4 PF13467.1 ETO22849.1 - 0.092 12.6 0.1 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 Ribbon-helix-helix domain SMC_hinge PF06470.8 ETO22849.1 - 0.098 12.6 0.1 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain SAM_PNT PF02198.11 ETO22850.1 - 3.7e-08 33.0 0.1 6.1e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_2 PF07647.12 ETO22850.1 - 0.00017 21.3 0.2 0.00052 19.8 0.2 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO22850.1 - 0.00049 20.2 1.4 0.0016 18.5 0.9 1.9 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) PDGF PF00341.12 ETO22850.1 - 0.22 11.6 5.1 0.71 10.0 3.2 2.1 1 1 1 2 2 2 0 PDGF/VEGF domain DUF272 PF03312.10 ETO22851.1 - 0.0083 16.3 3.0 0.016 15.4 2.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF272) DUF497 PF04365.8 ETO22852.1 - 0.14 12.0 2.0 0.35 10.8 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF497) Apis_Csd PF11671.3 ETO22852.1 - 2.7 7.7 10.1 7.8 6.2 7.0 1.9 1 0 0 1 1 1 0 Complementary sex determiner protein Tubulin PF00091.20 ETO22853.1 - 6.2e-42 143.8 0.0 9.3e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO22853.1 - 7.9e-22 77.6 0.1 4.4e-20 71.9 0.1 2.5 1 1 0 1 1 1 1 Tubulin C-terminal domain YlzJ PF14035.1 ETO22855.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 YlzJ-like protein HlyIII PF03006.15 ETO22855.1 - 0.93 8.8 12.2 1.8 7.8 8.5 1.6 1 1 0 1 1 1 0 Haemolysin-III related PMT_2 PF13231.1 ETO22855.1 - 1.7 8.4 15.9 3.7 7.4 5.6 2.3 1 1 1 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Helicase_C PF00271.26 ETO22856.1 - 0.018 14.9 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain SUV3_C PF12513.3 ETO22858.1 - 0.021 14.2 0.0 0.046 13.1 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 ETO22858.1 - 0.044 13.6 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 Helicase conserved C-terminal domain WD40 PF00400.27 ETO22859.1 - 1.9e-05 24.3 5.2 0.00019 21.1 0.2 2.9 2 1 0 2 2 2 1 WD domain, G-beta repeat CRT10 PF08728.5 ETO22859.1 - 0.0038 15.3 0.2 0.0045 15.0 0.1 1.0 1 0 0 1 1 1 1 CRT10 HAD PF12710.2 ETO22859.1 - 0.031 14.4 0.1 0.034 14.3 0.1 1.0 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Nup160 PF11715.3 ETO22859.1 - 0.12 10.4 0.1 0.12 10.4 0.0 1.0 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Tctex-1 PF03645.8 ETO22860.1 - 5.7e-13 48.5 0.9 6.8e-13 48.3 0.6 1.1 1 0 0 1 1 1 1 Tctex-1 family Nnf1 PF03980.9 ETO22860.1 - 0.024 14.6 0.0 0.026 14.5 0.0 1.1 1 0 0 1 1 1 0 Nnf1 Sec66 PF09802.4 ETO22860.1 - 0.032 13.6 0.1 0.035 13.5 0.1 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 DUF1902 PF08972.6 ETO22860.1 - 0.033 13.7 0.1 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) PI3K_rbd PF00794.13 ETO22860.1 - 0.098 12.6 0.1 0.22 11.4 0.0 1.5 2 0 0 2 2 2 0 PI3-kinase family, ras-binding domain Adaptin_N PF01602.15 ETO22860.1 - 0.11 10.8 0.0 0.13 10.5 0.0 1.0 1 0 0 1 1 1 0 Adaptin N terminal region ThiF PF00899.16 ETO22861.1 - 1.7e-31 108.8 0.6 2.4e-22 79.2 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.4 ETO22861.1 - 1e-17 63.2 1.8 1e-17 63.2 1.2 1.6 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 ETO22861.1 - 2.4e-05 24.4 0.0 4.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 ETO22861.1 - 0.00021 21.5 0.2 0.00079 19.6 0.1 1.8 1 1 0 1 1 1 1 Putative NAD(P)-binding Ldh_1_N PF00056.18 ETO22861.1 - 0.033 13.9 0.3 0.057 13.2 0.2 1.5 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain WD40 PF00400.27 ETO22862.1 - 3.5e-21 74.2 11.8 1.3e-09 37.5 1.1 4.9 6 0 0 6 6 6 3 WD domain, G-beta repeat Katanin_con80 PF13925.1 ETO22862.1 - 1.8e-14 53.7 4.1 4.5e-14 52.5 2.8 1.6 1 0 0 1 1 1 1 con80 domain of Katanin DUF4217 PF13959.1 ETO22863.1 - 1.3e-15 56.6 0.0 3.3e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 ETO22863.1 - 3.8e-13 49.0 0.2 1.1e-12 47.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Oxidored_q5_N PF01059.12 ETO22864.1 - 1.8 8.4 6.6 4.2 7.2 3.6 2.3 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus TMEM107 PF14995.1 ETO22864.1 - 7 6.7 9.7 0.58 10.2 1.5 2.5 3 1 0 3 3 3 0 Transmembrane protein HAP2-GCS1 PF10699.4 ETO22865.1 - 5.4e-19 67.8 0.1 1.2e-18 66.7 0.1 1.6 1 0 0 1 1 1 1 Male gamete fusion factor Ribosomal_S18 PF01084.15 ETO22867.1 - 8.5e-17 60.7 3.0 2.5e-15 56.0 0.0 2.7 3 0 0 3 3 3 2 Ribosomal protein S18 EF-hand_6 PF13405.1 ETO22868.1 - 7.2e-10 37.9 2.8 1.2e-05 24.7 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 ETO22868.1 - 3.9e-08 32.0 10.0 5.3e-06 25.3 0.3 2.9 3 0 0 3 3 2 2 EF hand EF-hand_7 PF13499.1 ETO22868.1 - 4.8e-06 26.6 4.8 9.8e-06 25.6 1.4 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 ETO22868.1 - 6.6e-05 22.0 4.2 0.00022 20.4 0.2 2.9 2 1 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 ETO22868.1 - 0.0001 21.8 5.8 0.018 14.6 0.6 2.9 1 1 2 3 3 3 2 EF-hand domain pair Sin3_corepress PF08295.7 ETO22868.1 - 0.0022 17.6 0.5 0.0062 16.2 0.1 1.9 1 1 1 2 2 2 1 Sin3 family co-repressor EF-hand_9 PF14658.1 ETO22868.1 - 0.038 13.9 2.4 1.8 8.5 0.2 3.2 2 1 1 3 3 3 0 EF-hand domain DUF501 PF04417.7 ETO22868.1 - 0.074 12.9 0.9 0.53 10.1 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF501) EF-hand_10 PF14788.1 ETO22868.1 - 0.11 12.1 0.1 0.11 12.1 0.1 3.0 3 1 1 4 4 4 0 EF hand SPARC_Ca_bdg PF10591.4 ETO22868.1 - 1.3 9.0 5.9 0.28 11.2 0.2 2.3 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF904 PF06005.7 ETO22868.1 - 1.8 8.9 11.4 1.3 9.3 5.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF904) DUF972 PF06156.8 ETO22868.1 - 5.2 7.4 8.1 3 8.2 3.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Pkinase PF00069.20 ETO22869.1 - 3.8e-07 29.5 0.1 5.1e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO22869.1 - 0.0011 18.1 0.2 0.0015 17.6 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UCH PF00443.24 ETO22870.1 - 1.3e-07 30.9 0.0 1.3e-07 30.9 0.0 3.4 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase TLD PF07534.11 ETO22871.1 - 7.5e-11 42.1 5.9 2.7e-10 40.3 4.1 1.9 1 1 0 1 1 1 1 TLD BSP_II PF05432.6 ETO22872.1 - 0.013 14.7 2.4 0.021 14.1 1.7 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Peptidase_M16_C PF05193.16 ETO22873.1 - 1.1e-05 25.1 0.0 2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain Tweety PF04906.8 ETO22874.1 - 0.025 13.0 0.6 0.025 13.0 0.4 1.5 2 0 0 2 2 2 0 Tweety Orthoreo_P10 PF07204.6 ETO22874.1 - 0.057 13.1 0.2 0.15 11.8 0.2 1.7 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 ETRAMP PF09716.5 ETO22874.1 - 0.58 10.1 2.6 1.3 9.0 1.8 1.6 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) TPR_11 PF13414.1 ETO22875.1 - 1.4e-05 24.6 3.2 0.00094 18.7 0.4 3.1 1 1 2 3 3 3 3 TPR repeat FAT PF02259.18 ETO22875.1 - 0.0034 16.4 0.1 0.0044 16.0 0.1 1.3 1 0 0 1 1 1 1 FAT domain TPR_19 PF14559.1 ETO22875.1 - 0.018 15.3 0.0 0.42 10.9 0.0 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat FolB PF02152.13 ETO22875.1 - 0.027 14.6 0.1 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 Dihydroneopterin aldolase TPR_17 PF13431.1 ETO22875.1 - 0.033 14.3 0.8 3.6 8.0 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF1469 PF07332.6 ETO22876.1 - 0.037 13.7 0.4 0.057 13.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DUF2077 PF09850.4 ETO22876.1 - 0.081 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) Lipoprotein_17 PF04200.7 ETO22876.1 - 0.14 12.2 8.3 0.2 11.8 5.7 1.2 1 0 0 1 1 1 0 Lipoprotein associated domain Secretin_N_2 PF07655.8 ETO22876.1 - 0.33 11.3 8.3 0.63 10.4 5.7 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Pex14_N PF04695.8 ETO22876.1 - 0.41 10.6 5.4 4.1 7.4 3.7 2.0 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2370 PF10176.4 ETO22876.1 - 1.5 8.1 6.8 3.1 7.0 4.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2370) DUF912 PF06024.7 ETO22876.1 - 4.8 7.2 10.0 1.5e+02 2.5 6.9 2.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Methyltransf_11 PF08241.7 ETO22877.1 - 1.3e-19 70.4 0.0 3.1e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETO22877.1 - 2e-19 69.9 0.0 2.8e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETO22877.1 - 1.1e-14 54.1 0.0 1.7e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 ETO22877.1 - 1.5e-14 53.8 0.0 2.1e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO22877.1 - 1.3e-11 44.7 0.0 2.3e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETO22877.1 - 2.9e-10 40.3 0.0 8.8e-10 38.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO22877.1 - 1e-07 32.4 0.0 1.7e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 ETO22877.1 - 0.00013 21.2 0.0 0.00022 20.4 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB MetW PF07021.7 ETO22877.1 - 0.0002 20.7 0.0 0.00037 19.9 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 ETO22877.1 - 0.0061 16.5 0.0 0.017 15.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Spc97_Spc98 PF04130.8 ETO22879.1 - 7.4e-19 67.4 8.8 5.8e-18 64.5 6.1 1.9 1 1 0 1 1 1 1 Spc97 / Spc98 family Spc97_Spc98 PF04130.8 ETO22880.1 - 2.9e-26 91.9 3.5 3.9e-26 91.4 2.4 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family G-gamma PF00631.17 ETO22881.1 - 0.00025 20.7 0.3 0.00044 19.9 0.2 1.4 1 0 0 1 1 1 1 GGL domain DivIC PF04977.10 ETO22881.1 - 0.0015 17.9 1.0 0.0029 17.0 0.7 1.5 1 0 0 1 1 1 1 Septum formation initiator DUF4140 PF13600.1 ETO22881.1 - 0.089 13.2 0.6 0.12 12.8 0.4 1.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF4164 PF13747.1 ETO22881.1 - 0.096 12.8 1.0 0.13 12.4 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) BID PF06393.6 ETO22884.1 - 0.032 13.5 0.1 0.037 13.3 0.1 1.2 1 0 0 1 1 1 0 BH3 interacting domain (BID) CENP-F_leu_zip PF10473.4 ETO22885.1 - 3.7e-05 23.5 23.1 0.0037 17.1 4.1 2.2 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2968 PF11180.3 ETO22885.1 - 0.00037 19.9 2.7 0.00037 19.9 1.9 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF2968) DUF1875 PF08961.5 ETO22885.1 - 0.00061 19.1 2.8 0.085 12.1 1.0 2.2 1 1 0 2 2 2 1 Domain of unknown function (DUF1875) DUF4201 PF13870.1 ETO22885.1 - 0.0011 18.4 13.1 0.0011 18.4 9.1 2.2 1 1 0 2 2 2 1 Domain of unknown function (DUF4201) bZIP_1 PF00170.16 ETO22885.1 - 0.0056 16.5 18.4 0.01 15.7 1.6 3.5 1 1 2 3 3 3 2 bZIP transcription factor Reo_sigmaC PF04582.7 ETO22885.1 - 0.0057 15.8 6.6 0.0057 15.8 4.6 2.0 1 1 1 2 2 2 1 Reovirus sigma C capsid protein Spectrin PF00435.16 ETO22885.1 - 0.0069 16.6 17.0 0.013 15.7 5.9 2.3 1 1 1 2 2 2 1 Spectrin repeat DivIC PF04977.10 ETO22885.1 - 0.008 15.6 17.5 0.084 12.3 1.5 3.0 1 1 2 3 3 3 2 Septum formation initiator BLOC1_2 PF10046.4 ETO22885.1 - 0.0097 16.0 19.0 0.041 14.0 3.0 2.3 1 1 2 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6 PF04111.7 ETO22885.1 - 0.016 14.2 23.8 0.018 14.0 6.5 1.9 1 1 1 2 2 2 0 Autophagy protein Apg6 DASH_Hsk3 PF08227.6 ETO22885.1 - 0.02 15.0 1.2 0.02 15.0 0.9 3.7 3 1 0 3 3 2 0 DASH complex subunit Hsk3 like AAA_13 PF13166.1 ETO22885.1 - 0.032 12.7 11.7 0.042 12.3 8.1 1.2 1 0 0 1 1 1 0 AAA domain TPR_MLP1_2 PF07926.7 ETO22885.1 - 0.038 13.7 25.3 0.016 14.9 12.1 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.6 ETO22885.1 - 0.039 12.6 17.3 0.054 12.1 12.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.4 ETO22885.1 - 0.05 12.5 20.0 0.36 9.7 3.2 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TBPIP PF07106.8 ETO22885.1 - 0.052 13.1 21.7 0.94 9.0 8.5 2.8 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GAS PF13851.1 ETO22885.1 - 0.069 12.3 24.1 0.35 10.0 5.1 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 ETO22885.1 - 0.073 13.4 20.2 1.2 9.4 7.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF904 PF06005.7 ETO22885.1 - 0.1 12.9 21.2 0.046 14.0 2.5 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF904) ADIP PF11559.3 ETO22885.1 - 0.11 12.4 27.3 0.55 10.1 7.6 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TMF_TATA_bd PF12325.3 ETO22885.1 - 0.15 11.7 22.0 1.4 8.6 4.1 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Fez1 PF06818.10 ETO22885.1 - 0.16 11.9 14.2 0.24 11.3 9.8 1.2 1 0 0 1 1 1 0 Fez1 Herpes_BLRF2 PF05812.7 ETO22885.1 - 0.16 11.7 12.4 0.51 10.1 1.7 2.5 1 1 0 2 2 2 0 Herpesvirus BLRF2 protein ATG16 PF08614.6 ETO22885.1 - 0.21 11.4 22.5 0.69 9.7 10.1 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) IncA PF04156.9 ETO22885.1 - 0.21 11.1 25.0 2.2 7.8 17.1 2.0 1 1 0 1 1 1 0 IncA protein HrpB7 PF09486.5 ETO22885.1 - 0.22 11.4 10.7 0.4 10.5 0.8 2.7 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) ERM PF00769.14 ETO22885.1 - 0.24 10.9 24.1 2 7.9 8.2 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Spc42p PF11544.3 ETO22885.1 - 0.26 11.2 15.1 0.48 10.3 2.4 2.7 2 1 0 2 2 2 0 Spindle pole body component Spc42p WXG100 PF06013.7 ETO22885.1 - 0.29 11.1 9.3 6.3 6.8 0.0 3.3 3 1 0 3 3 3 0 Proteins of 100 residues with WXG Tropomyosin_1 PF12718.2 ETO22885.1 - 0.5 10.1 19.5 1.1 9.1 12.5 2.0 1 1 0 1 1 1 0 Tropomyosin like Seryl_tRNA_N PF02403.17 ETO22885.1 - 0.54 10.2 17.7 4.6 7.2 0.6 2.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4200 PF13863.1 ETO22885.1 - 0.72 9.8 22.2 2.1 8.2 9.5 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) HlyD PF00529.15 ETO22885.1 - 0.82 8.9 9.2 1.3 8.2 6.4 1.3 1 0 0 1 1 1 0 HlyD family secretion protein Myosin_tail_1 PF01576.14 ETO22885.1 - 0.9 7.1 20.7 2.5 5.7 3.0 1.7 1 1 0 1 1 1 0 Myosin tail Phage_GPO PF05929.6 ETO22885.1 - 0.99 8.5 9.0 1.4 8.1 6.2 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4559 PF15112.1 ETO22885.1 - 1.1 8.3 15.3 1.6 7.8 10.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) DUF342 PF03961.8 ETO22885.1 - 1.4 7.2 15.9 0.55 8.5 1.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) SlyX PF04102.7 ETO22885.1 - 1.8 8.9 18.5 0.91 9.9 6.1 3.2 1 1 0 3 3 3 0 SlyX DUF869 PF05911.6 ETO22885.1 - 1.9 6.6 20.9 0.92 7.6 7.7 1.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) Syntaxin-6_N PF09177.6 ETO22885.1 - 2.5 8.5 13.2 7.3 7.0 0.9 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF3584 PF12128.3 ETO22885.1 - 2.7 5.2 20.7 6.1 4.0 14.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4140 PF13600.1 ETO22885.1 - 2.8 8.4 13.2 3.1 8.2 0.5 3.4 1 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF2205 PF10224.4 ETO22885.1 - 2.9 7.5 17.5 7 6.2 1.0 3.0 1 1 2 3 3 3 0 Predicted coiled-coil protein (DUF2205) DUF4337 PF14235.1 ETO22885.1 - 3.2 7.5 12.9 3 7.6 2.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Nup54 PF13874.1 ETO22885.1 - 3.6 7.2 20.4 0.27 10.8 3.1 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Macoilin PF09726.4 ETO22885.1 - 3.6 5.7 19.8 7.5 4.6 13.8 1.4 1 1 0 1 1 1 0 Transmembrane protein Cortex-I_coil PF09304.5 ETO22885.1 - 3.7 7.6 16.1 16 5.6 7.0 2.3 2 0 0 2 2 2 0 Cortexillin I, coiled coil DUF948 PF06103.6 ETO22885.1 - 4.3 7.2 15.4 4.4 7.2 0.4 3.4 2 1 2 4 4 3 0 Bacterial protein of unknown function (DUF948) DUF4404 PF14357.1 ETO22885.1 - 4.6 7.7 16.4 5.7 7.4 2.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) V_ATPase_I PF01496.14 ETO22885.1 - 4.7 4.9 17.6 1.5 6.5 5.7 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DivIVA PF05103.8 ETO22885.1 - 5.5 7.0 17.7 21 5.1 5.0 3.2 1 1 1 2 2 2 0 DivIVA protein DUF4175 PF13779.1 ETO22885.1 - 5.9 4.4 18.0 7.7 4.0 12.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Occludin_ELL PF07303.8 ETO22885.1 - 7.2 7.4 15.5 11 6.8 5.3 2.2 1 1 1 2 2 2 0 Occludin homology domain DUF3166 PF11365.3 ETO22885.1 - 7.2 7.1 10.5 1.5 9.3 2.2 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3166) CENP-Q PF13094.1 ETO22885.1 - 7.6 6.5 25.0 56 3.7 17.3 2.1 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2730 PF10805.3 ETO22885.1 - 7.9 6.2 9.8 17 5.1 0.2 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2730) DUF641 PF04859.7 ETO22885.1 - 7.9 6.2 14.5 9.9 5.9 5.3 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) FlaC_arch PF05377.6 ETO22885.1 - 8.3 6.3 7.6 19 5.2 0.8 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.7 ETO22885.1 - 8.9 6.6 12.5 14 6.0 4.5 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Sec8_exocyst PF04048.9 ETO22885.1 - 9.7 5.8 19.7 5 6.7 7.8 2.3 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain ATG11 PF10377.4 ETO22886.1 - 0.0014 18.4 0.0 0.0025 17.7 0.0 1.4 2 0 0 2 2 2 1 Autophagy-related protein 11 Las1 PF04031.8 ETO22887.1 - 2.9e-25 88.7 2.4 2.9e-25 88.7 1.7 1.8 2 0 0 2 2 2 1 Las1-like DUF2052 PF09747.4 ETO22887.1 - 0.014 15.3 0.9 0.074 12.9 0.3 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) End_N_terminal PF12218.3 ETO22887.1 - 0.11 11.9 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase Med26 PF08711.6 ETO22889.1 - 2.6e-10 39.6 1.9 8.1e-10 38.0 1.3 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Decorin_bind PF02352.10 ETO22889.1 - 0.042 13.8 6.8 0.015 15.2 3.0 1.6 1 1 1 2 2 2 0 Decorin binding protein Med3 PF11593.3 ETO22889.1 - 0.079 12.1 18.6 0.12 11.5 12.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal IF2_N PF04760.10 ETO22889.1 - 0.08 12.6 1.1 0.2 11.3 0.0 2.2 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region DUF3713 PF12506.3 ETO22889.1 - 0.19 11.7 15.7 0.03 14.4 6.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3713) DUF1180 PF06679.7 ETO22889.1 - 0.22 11.4 9.9 0.35 10.7 6.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Mlo PF03094.10 ETO22889.1 - 2.2 6.2 4.9 7 4.6 3.1 1.9 1 1 1 2 2 2 0 Mlo family Macoilin PF09726.4 ETO22889.1 - 8 4.6 12.6 9.5 4.3 8.7 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF1430 PF07242.6 ETO22890.1 - 0.36 10.9 8.4 3.2 7.8 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1430) DUF2631 PF10939.3 ETO22890.1 - 0.58 10.0 2.4 3 7.7 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2631) O-antigen_lig PF13425.1 ETO22890.1 - 0.76 9.7 11.4 0.62 10.0 1.9 2.9 1 1 2 3 3 3 0 O-antigen ligase like membrane protein YfhO PF09586.5 ETO22890.1 - 0.86 7.5 12.2 0.24 9.3 6.1 1.7 1 1 1 2 2 2 0 Bacterial membrane protein YfhO ABC2_membrane_5 PF13346.1 ETO22890.1 - 1.9 7.7 10.3 0.043 13.1 0.9 2.3 2 1 0 2 2 2 0 ABC-2 family transporter protein G-alpha PF00503.15 ETO22891.1 - 2.2e-48 164.9 11.6 4.1e-47 160.7 8.1 2.3 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO22891.1 - 0.0002 20.6 0.9 0.023 13.9 0.1 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETO22891.1 - 0.13 12.1 0.1 4.6 7.2 0.1 2.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase SprA-related PF12118.3 ETO22892.1 - 1.2 8.3 18.4 1.7 7.8 12.8 1.2 1 0 0 1 1 1 0 SprA-related family DUF1849 PF08904.6 ETO22893.1 - 0.032 13.5 2.0 0.037 13.3 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1849) DUF3313 PF11769.3 ETO22893.1 - 0.11 11.8 0.2 0.27 10.5 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3313) TPD52 PF04201.10 ETO22893.1 - 0.11 12.1 4.6 2.1 8.0 0.1 2.3 2 0 0 2 2 2 0 Tumour protein D52 family PGBA_C PF15437.1 ETO22893.1 - 3.2 7.9 14.0 0.13 12.4 4.8 2.1 2 1 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal PRP1_N PF06424.7 ETO22893.1 - 9.3 6.5 9.1 0.54 10.5 2.5 1.7 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal DUF2542 PF10808.3 ETO22894.1 - 0.12 12.6 1.4 14 6.0 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2542) PUB PF09409.5 ETO22895.1 - 0.0018 17.9 3.4 0.0089 15.7 2.3 2.2 1 1 0 1 1 1 1 PUB domain DUF3727 PF12527.3 ETO22896.1 - 0.027 14.5 0.4 5.1 7.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3727) NT-C2 PF10358.4 ETO22897.1 - 4.4e-05 23.0 0.0 0.00021 20.7 0.0 2.1 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Phage-scaffold PF09306.5 ETO22897.1 - 0.03 13.4 0.1 0.039 13.1 0.1 1.1 1 0 0 1 1 1 0 Bacteriophage, scaffolding protein DUF2443 PF10398.4 ETO22897.1 - 0.048 13.4 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) Trp_dioxygenase PF03301.8 ETO22897.1 - 0.059 12.4 0.1 0.067 12.2 0.1 1.0 1 0 0 1 1 1 0 Tryptophan 2,3-dioxygenase VPS9 PF02204.13 ETO22898.1 - 2.6e-11 43.4 1.1 5.1e-11 42.5 0.0 2.1 3 0 0 3 3 3 1 Vacuolar sorting protein 9 (VPS9) domain Synthase_beta PF11421.3 ETO22900.1 - 0.014 16.0 1.2 0.066 13.8 0.2 2.6 2 0 0 2 2 2 0 ATP synthase F1 beta subunit CENP-M PF11111.3 ETO22900.1 - 0.051 12.7 1.0 0.12 11.5 0.7 1.6 1 0 0 1 1 1 0 Centromere protein M (CENP-M) ABC-3 PF00950.12 ETO22901.1 - 0.011 15.0 0.4 0.014 14.6 0.2 1.2 1 0 0 1 1 1 0 ABC 3 transport family NPR3 PF03666.8 ETO22902.1 - 0.04 12.4 0.9 0.057 11.9 0.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RGS PF00615.14 ETO22903.1 - 5.8e-06 26.4 1.0 1.1e-05 25.5 0.7 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain Pkinase PF00069.20 ETO22904.1 - 3.9e-22 78.6 6.3 6e-22 78.0 4.4 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO22904.1 - 2.6e-16 59.5 2.1 5.6e-16 58.3 1.4 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 ETO22904.1 - 0.0032 16.8 0.3 0.0071 15.7 0.2 1.6 1 0 0 1 1 1 1 RIO1 family DFF40 PF09230.5 ETO22904.1 - 0.014 14.7 0.2 0.017 14.4 0.1 1.1 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa NDUF_C2 PF06374.6 ETO22904.1 - 0.075 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) DUF2779 PF11074.3 ETO22904.1 - 0.096 12.7 0.5 0.13 12.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function(DUF2779) Borrelia_P83 PF05262.6 ETO22906.1 - 6e-05 21.5 35.0 6e-05 21.5 24.2 2.2 1 1 1 2 2 2 1 Borrelia P83/100 protein TSC22 PF01166.13 ETO22907.1 - 0.00058 19.7 15.2 0.0041 17.0 0.3 3.3 2 1 2 4 4 4 2 TSC-22/dip/bun family CCDC84 PF14968.1 ETO22907.1 - 0.03 13.8 1.2 0.04 13.4 0.8 1.0 1 0 0 1 1 1 0 Coiled coil protein 84 DivIC PF04977.10 ETO22907.1 - 0.2 11.1 15.6 0.31 10.5 2.3 3.3 3 0 0 3 3 3 0 Septum formation initiator DUF4315 PF14193.1 ETO22907.1 - 0.21 11.5 15.8 0.24 11.3 0.2 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4315) HAUS6_N PF14661.1 ETO22907.1 - 0.48 9.7 10.2 0.57 9.4 7.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Vpu PF00558.14 ETO22907.1 - 0.5 9.9 6.3 0.35 10.4 2.2 2.2 1 1 1 2 2 2 0 Vpu protein FlxA PF14282.1 ETO22907.1 - 0.83 9.6 19.8 0.22 11.4 1.5 3.0 2 1 1 3 3 3 0 FlxA-like protein bZIP_1 PF00170.16 ETO22907.1 - 2.5 8.0 16.1 4 7.4 0.5 3.2 3 1 0 3 3 3 0 bZIP transcription factor AAA_13 PF13166.1 ETO22907.1 - 3.1 6.1 17.6 8.2 4.7 12.2 1.5 1 1 0 1 1 1 0 AAA domain Fzo_mitofusin PF04799.8 ETO22907.1 - 3.1 7.1 11.0 5.2 6.4 0.0 2.9 2 1 1 3 3 3 0 fzo-like conserved region BTV_NS2 PF04514.7 ETO22907.1 - 7.2 5.3 10.7 9.2 5.0 7.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 14-3-3 PF00244.15 ETO22908.1 - 6.1e-10 38.5 11.0 1.8e-08 33.7 7.6 2.1 1 1 0 1 1 1 1 14-3-3 protein Dna2 PF08696.6 ETO22908.1 - 0.0048 16.2 0.7 0.011 15.1 0.5 1.5 1 0 0 1 1 1 1 DNA replication factor Dna2 PH_6 PF15406.1 ETO22908.1 - 0.017 15.1 0.7 0.062 13.3 0.0 2.2 3 0 0 3 3 3 0 Pleckstrin homology domain CENP-B_dimeris PF09026.5 ETO22908.1 - 0.046 13.9 1.0 0.12 12.6 0.7 1.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF2457 PF10446.4 ETO22908.1 - 0.048 12.3 4.7 0.066 11.9 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF912 PF06024.7 ETO22908.1 - 0.053 13.5 4.7 0.12 12.4 3.3 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Vfa1 PF08432.5 ETO22908.1 - 1.3 9.0 10.4 0.61 10.0 5.5 1.7 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1774 PF08611.5 ETO22909.1 - 1.6 8.9 4.9 1.3 9.2 0.1 2.7 3 0 0 3 3 3 0 Fungal protein of unknown function (DUF1774) ETRAMP PF09716.5 ETO22910.1 - 0.0011 18.8 1.3 0.0038 17.1 0.9 2.1 1 1 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) DUF3619 PF12279.3 ETO22910.1 - 0.05 13.6 0.7 0.42 10.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) DUF2681 PF10883.3 ETO22910.1 - 0.057 13.6 1.5 0.31 11.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF4231 PF14015.1 ETO22910.1 - 0.11 12.4 0.4 0.18 11.8 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) Syndecan PF01034.15 ETO22910.1 - 0.12 11.9 0.2 0.27 10.8 0.2 1.5 1 0 0 1 1 1 0 Syndecan domain Peptidase_C50 PF03568.12 ETO22911.1 - 1.3e-47 162.3 1.7 1.3e-47 162.3 1.2 3.5 2 1 0 2 2 2 1 Peptidase family C50 TPR_12 PF13424.1 ETO22911.1 - 0.002 18.0 2.0 2.3 8.2 0.2 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO22912.1 - 0.0031 17.8 0.1 0.045 14.2 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 ETO22912.1 - 0.084 13.3 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat A_deaminase PF00962.17 ETO22913.1 - 3.3e-11 42.6 1.3 3.4e-10 39.3 0.3 2.0 2 0 0 2 2 2 2 Adenosine/AMP deaminase Kelch_6 PF13964.1 ETO22914.1 - 0.022 14.9 0.0 0.18 12.0 0.1 2.6 2 0 0 2 2 2 0 Kelch motif CENP-T PF15511.1 ETO22915.1 - 1.7 7.8 36.4 2.2 7.4 25.2 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Skp1 PF01466.14 ETO22916.1 - 1.8e-18 66.2 0.0 3.5e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 ETO22916.1 - 0.0028 17.7 0.8 0.015 15.3 0.0 2.4 3 0 0 3 3 3 1 Skp1 family, tetramerisation domain Herpes_glycop PF01528.11 ETO22917.1 - 0.0071 15.0 3.9 0.013 14.2 2.7 1.4 1 0 0 1 1 1 1 Herpesvirus glycoprotein M DUF4229 PF14012.1 ETO22917.1 - 0.021 14.6 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) DUF1394 PF07159.7 ETO22918.1 - 1.3e-09 37.5 0.7 3.3e-09 36.3 0.5 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1394) Resolvase PF00239.16 ETO22918.1 - 0.095 12.5 0.1 0.17 11.7 0.0 1.4 1 1 0 1 1 1 0 Resolvase, N terminal domain DUF2450 PF10475.4 ETO22919.1 - 4.5e-18 65.1 12.2 2.9e-17 62.5 7.1 2.2 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) DUF2457 PF10446.4 ETO22919.1 - 0.00039 19.2 5.8 0.00049 18.9 4.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) DUF2407_C PF13373.1 ETO22919.1 - 0.13 12.1 7.2 0.31 10.9 5.0 1.7 1 0 0 1 1 1 0 DUF2407 C-terminal domain Secretin_N_2 PF07655.8 ETO22919.1 - 0.3 11.4 17.2 0.23 11.8 10.5 1.8 2 0 0 2 2 2 0 Secretin N-terminal domain FA_hydroxylase PF04116.8 ETO22920.1 - 4.7e-09 36.6 21.3 5.1e-09 36.5 12.6 2.6 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily TAP_C PF03943.8 ETO22920.1 - 0.063 12.7 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 TAP C-terminal domain DUF3800 PF12686.2 ETO22921.1 - 0.0033 17.1 0.4 0.0056 16.3 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3800) Mitofilin PF09731.4 ETO22921.1 - 0.0092 14.6 10.4 0.012 14.2 7.2 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF3824 PF12868.2 ETO22921.1 - 0.6 11.0 10.7 0.14 13.0 3.4 2.2 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) SpoIIIAH PF12685.2 ETO22921.1 - 1.7 8.0 14.9 0.47 9.9 6.9 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein Mem_trans PF03547.13 ETO22921.1 - 4.5 5.4 8.8 6.3 4.9 6.1 1.3 1 1 0 1 1 1 0 Membrane transport protein DUF1510 PF07423.6 ETO22921.1 - 4.7 6.5 25.1 0.19 11.0 12.7 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1510) ATP-synt_C PF00137.16 ETO22924.1 - 1.7e-27 95.0 32.2 1.4e-17 63.3 9.5 3.0 3 0 0 3 3 3 2 ATP synthase subunit C DUF3961 PF13106.1 ETO22924.1 - 0.035 13.6 0.6 0.035 13.6 0.4 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3961) GerA PF03323.8 ETO22924.1 - 3.3 5.7 5.2 12 3.8 0.4 2.3 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein SLIDE PF09111.5 ETO22925.1 - 0.0011 18.7 1.6 0.0011 18.7 1.1 3.2 3 1 1 4 4 4 1 SLIDE NACHT PF05729.7 ETO22926.1 - 5.7e-08 32.5 0.0 8.8e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Sarcoglycan_2 PF05510.8 ETO22926.1 - 0.042 12.1 0.2 0.063 11.5 0.1 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Serglycin PF04360.7 ETO22927.1 - 0.01 15.5 2.0 0.034 13.8 0.8 1.9 2 0 0 2 2 2 0 Serglycin Zip PF02535.17 ETO22927.1 - 0.36 9.8 3.5 0.35 9.8 2.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter GlcNAc PF11397.3 ETO22928.1 - 4.4e-37 127.9 0.1 5.3e-37 127.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) Glyco_trans_2_3 PF13632.1 ETO22928.1 - 0.04 13.6 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family group 2 DUF1788 PF08747.6 ETO22929.1 - 0.00098 18.9 0.5 0.0016 18.3 0.3 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1788) YtpI PF14007.1 ETO22929.1 - 0.038 13.9 0.5 0.079 12.8 0.3 1.5 1 0 0 1 1 1 0 YtpI-like protein LIME1 PF15332.1 ETO22929.1 - 0.062 12.5 2.5 0.094 11.9 1.7 1.2 1 0 0 1 1 1 0 Lck-interacting transmembrane adapter 1 Folliculin PF11704.3 ETO22929.1 - 0.081 12.5 3.8 0.71 9.4 1.2 2.0 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport tRNA_synt_1c_R1 PF04558.10 ETO22929.1 - 0.15 11.6 4.2 0.22 11.0 2.9 1.2 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 OST3_OST6 PF04756.8 ETO22929.1 - 0.15 11.6 1.3 1.8 8.1 0.3 2.2 1 1 0 2 2 2 0 OST3 / OST6 family NOT2_3_5 PF04153.13 ETO22929.1 - 0.31 10.9 3.9 0.15 11.9 1.1 1.6 2 0 0 2 2 2 0 NOT2 / NOT3 / NOT5 family DUF1764 PF08576.5 ETO22929.1 - 4.3 8.1 9.6 2 9.2 2.8 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) SLD3 PF08639.5 ETO22929.1 - 9.5 4.7 16.5 1.4 7.5 8.1 1.7 1 1 0 2 2 2 0 DNA replication regulator SLD3 PYC_OADA PF02436.13 ETO22930.1 - 3e-20 72.4 0.2 4.2e-20 71.9 0.2 1.3 1 0 0 1 1 1 1 Conserved carboxylase domain HMGL-like PF00682.14 ETO22930.1 - 8.6e-20 71.4 0.6 2.2e-19 70.0 0.1 1.8 2 0 0 2 2 2 1 HMGL-like COX6C PF02937.10 ETO22930.1 - 0.12 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc Pkinase PF00069.20 ETO22931.1 - 3.6e-29 101.7 0.0 1.9e-28 99.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO22931.1 - 0.00021 20.4 0.3 0.097 11.7 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Menin PF05053.8 ETO22931.1 - 4.8 5.2 9.2 6.5 4.7 6.4 1.1 1 0 0 1 1 1 0 Menin Pneumo_att_G PF05539.6 ETO22932.1 - 2.1 7.6 11.6 2.5 7.3 8.0 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DDHD PF02862.12 ETO22932.1 - 3.3 7.4 7.1 3.9 7.2 4.9 1.1 1 0 0 1 1 1 0 DDHD domain Fibrillarin PF01269.12 ETO22933.1 - 1.8e-89 298.5 0.0 2e-73 246.0 0.0 2.3 2 1 0 2 2 2 2 Fibrillarin GCD14 PF08704.5 ETO22933.1 - 0.027 13.9 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Ras PF00071.17 ETO22934.1 - 8.5e-31 106.5 0.8 2.2e-30 105.1 0.6 1.7 1 1 0 1 1 1 1 Ras family Miro PF08477.8 ETO22934.1 - 5.5e-09 36.5 0.7 1.1e-08 35.5 0.2 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO22934.1 - 0.0032 16.7 0.2 0.015 14.5 0.2 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family GDI PF00996.13 ETO22935.1 - 2.6e-69 233.6 0.0 6.1e-41 140.1 0.0 2.0 1 1 1 2 2 2 2 GDP dissociation inhibitor Epimerase PF01370.16 ETO22937.1 - 6.1e-07 29.1 0.0 9.5e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETO22937.1 - 1.7e-05 24.8 0.0 3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF4215 PF13948.1 ETO22937.1 - 0.035 14.3 0.2 0.082 13.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4215) LEA_4 PF02987.11 ETO22937.1 - 0.21 11.4 10.5 0.56 10.1 7.2 1.7 1 1 0 1 1 1 0 Late embryogenesis abundant protein EMP24_GP25L PF01105.19 ETO22938.1 - 2.3e-18 66.5 0.1 2.8e-18 66.2 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4169 PF13770.1 ETO22939.1 - 0.017 15.0 0.8 0.035 14.0 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4169) WD40 PF00400.27 ETO22941.1 - 2.6e-63 207.7 17.8 7.7e-13 47.7 0.1 7.1 8 0 0 8 8 8 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO22941.1 - 3.6e-06 26.8 0.6 0.006 16.3 0.0 3.1 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO22941.1 - 6.1e-06 24.7 2.5 0.41 8.8 0.1 3.2 2 1 1 3 3 3 3 Cytochrome D1 heme domain Nup160 PF11715.3 ETO22941.1 - 1.9e-05 23.0 13.1 0.15 10.2 0.2 4.6 2 2 3 5 5 5 4 Nucleoporin Nup120/160 Nbas_N PF15492.1 ETO22941.1 - 0.00051 19.2 0.7 0.72 8.9 0.0 3.1 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Coatomer_WDAD PF04053.9 ETO22941.1 - 0.022 13.5 5.1 0.17 10.6 0.6 2.9 2 2 1 3 3 3 0 Coatomer WD associated region PD40 PF07676.7 ETO22941.1 - 0.11 12.1 2.5 3.9 7.2 0.1 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat WW PF00397.21 ETO22943.1 - 4.8e-07 29.5 0.5 4.8e-07 29.5 0.3 2.3 2 0 0 2 2 2 1 WW domain Dimeth_Pyl PF09505.5 ETO22943.1 - 0.086 11.0 0.0 0.15 10.3 0.0 1.3 1 0 0 1 1 1 0 Dimethylamine methyltransferase (Dimeth_PyL) TFIIA PF03153.8 ETO22943.1 - 1.5 8.6 17.0 2.1 8.1 11.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_LBD PF02931.18 ETO22944.1 - 0.041 13.0 1.2 0.052 12.6 0.5 1.5 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel ligand binding domain NST1 PF13945.1 ETO22944.1 - 4 7.4 8.1 0.62 10.0 0.5 2.1 2 0 0 2 2 2 0 Salt tolerance down-regulator Nckap1 PF09735.4 ETO22945.1 - 1.7e-12 45.7 4.8 7.2e-09 33.7 0.5 2.0 1 1 1 2 2 2 2 Membrane-associated apoptosis protein CH PF00307.26 ETO22946.1 - 7.2e-05 22.7 0.0 0.00022 21.2 0.0 1.8 2 0 0 2 2 2 1 Calponin homology (CH) domain CBP PF12192.3 ETO22946.1 - 0.038 13.9 0.1 0.065 13.1 0.1 1.3 1 0 0 1 1 1 0 Fungal calcium binding protein Tantalus PF15386.1 ETO22947.1 - 0.23 11.2 6.1 0.067 12.9 1.3 2.3 2 0 0 2 2 2 0 Drosophila Tantalus-like Ndc1_Nup PF09531.5 ETO22947.1 - 4.6 5.5 9.4 5.8 5.2 6.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup XAP5 PF04921.9 ETO22947.1 - 6.6 6.2 15.4 17 4.8 9.2 2.0 1 1 1 2 2 2 0 XAP5, circadian clock regulator UCH PF00443.24 ETO22948.1 - 2.6e-40 138.2 4.5 3.9e-40 137.6 3.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO22948.1 - 1.1e-20 74.3 2.6 2.2e-20 73.3 1.8 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CSTF2_hinge PF14327.1 ETO22948.1 - 0.17 11.9 0.6 0.52 10.4 0.0 2.1 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 Zip PF02535.17 ETO22949.1 - 0.076 12.0 0.5 0.15 11.0 0.3 1.5 1 1 0 1 1 1 0 ZIP Zinc transporter RCR PF12273.3 ETO22949.1 - 0.24 11.9 3.0 0.36 11.3 2.1 1.2 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Ank_4 PF13637.1 ETO22953.1 - 3.1e-16 59.4 1.8 3.6e-06 27.3 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO22953.1 - 1e-15 57.8 0.5 1.1e-08 35.3 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETO22953.1 - 8.8e-15 53.6 4.3 0.00027 20.5 0.1 3.8 3 1 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 ETO22953.1 - 4.6e-12 45.7 0.4 0.00026 21.1 0.0 4.5 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO22953.1 - 1e-11 43.8 3.4 0.00025 20.9 0.1 3.8 3 1 0 3 3 3 2 Ankyrin repeat AhpC-TSA_2 PF13911.1 ETO22953.1 - 0.0065 16.3 0.0 0.015 15.2 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme LAM_C PF12544.3 ETO22953.1 - 0.065 13.2 0.6 0.12 12.4 0.0 1.6 2 0 0 2 2 2 0 Lysine-2,3-aminomutase DUF3112 PF11309.3 ETO22955.1 - 0.041 13.6 7.5 0.21 11.3 2.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) DUF872 PF05915.7 ETO22955.1 - 0.088 12.6 0.0 0.088 12.6 0.0 3.6 3 2 1 4 4 4 0 Eukaryotic protein of unknown function (DUF872) Daxx PF03344.10 ETO22955.1 - 1.8 6.9 44.0 3.5 6.0 30.5 1.5 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 ETO22955.1 - 5.7 4.7 49.0 9.4 4.0 33.9 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 ETO22955.1 - 5.8 4.8 38.9 12 3.7 27.0 1.5 1 0 0 1 1 1 0 CDC45-like protein Kelch_6 PF13964.1 ETO22956.1 - 1.5e-06 28.0 0.7 0.00012 22.1 0.1 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 ETO22956.1 - 3.7e-06 26.9 0.0 7.9e-05 22.7 0.0 2.5 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO22956.1 - 6.4e-06 25.6 0.4 4.2e-05 23.0 0.0 2.5 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETO22956.1 - 8.7e-06 25.4 0.0 0.00013 21.6 0.0 2.3 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO22956.1 - 3.6e-05 23.3 0.6 0.0022 17.6 0.1 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 ETO22956.1 - 0.02 14.8 0.6 0.19 11.7 0.2 2.6 3 0 0 3 3 3 0 Kelch motif CYTH PF01928.16 ETO22956.1 - 0.049 13.3 0.1 0.08 12.6 0.1 1.3 1 0 0 1 1 1 0 CYTH domain WD40 PF00400.27 ETO22957.1 - 4.2e-68 222.9 20.4 3.8e-12 45.5 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO22957.1 - 1.6e-08 34.4 0.6 0.026 14.2 0.1 3.5 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ricin_B_lectin PF00652.17 ETO22957.1 - 1.5e-07 31.4 8.0 0.0029 17.6 0.9 2.7 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain Cytochrom_D1 PF02239.11 ETO22957.1 - 1.5e-07 30.0 1.6 0.0049 15.2 0.0 3.4 1 1 3 4 4 4 3 Cytochrome D1 heme domain Nup160 PF11715.3 ETO22957.1 - 3.6e-06 25.4 13.9 0.06 11.4 0.1 5.5 1 1 4 6 6 6 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO22957.1 - 0.00026 19.8 6.8 0.51 9.0 0.4 4.2 1 1 1 2 2 2 2 Nup133 N terminal like Nbas_N PF15492.1 ETO22957.1 - 0.0013 17.8 1.8 2.2 7.2 0.0 4.3 1 1 4 5 5 5 1 Neuroblastoma-amplified sequence, N terminal SusE PF14292.1 ETO22957.1 - 0.0047 16.7 0.1 21 4.9 0.0 4.0 3 1 1 4 4 4 0 SusE outer membrane protein DUF1258 PF06869.7 ETO22957.1 - 0.0058 15.7 2.3 0.13 11.2 0.2 2.7 1 1 0 2 2 2 1 Protein of unknown function (DUF1258) Resistin PF06954.6 ETO22957.1 - 0.0061 16.8 2.0 29 5.0 0.1 4.2 2 1 1 4 4 4 0 Resistin IKI3 PF04762.7 ETO22957.1 - 0.053 11.3 4.5 1 7.0 0.1 2.7 1 1 2 3 3 3 0 IKI3 family DUF3312 PF11768.3 ETO22957.1 - 0.073 11.2 3.6 2.4 6.2 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3312) NHL PF01436.16 ETO22957.1 - 0.13 12.2 0.5 3.2 7.8 0.0 3.2 3 0 0 3 3 3 0 NHL repeat PD40 PF07676.7 ETO22957.1 - 0.24 11.1 9.1 6.4 6.5 0.0 5.3 7 1 0 7 7 7 0 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.2 ETO22957.1 - 0.32 10.7 6.1 14 5.3 1.3 3.8 3 1 0 3 3 3 0 Transcription factor IIIC subunit delta N-term Clathrin_propel PF01394.15 ETO22957.1 - 0.49 10.7 2.3 1.6 9.2 0.2 2.9 3 0 0 3 3 3 0 Clathrin propeller repeat WD40 PF00400.27 ETO22958.1 - 9.1e-64 209.2 31.6 4.8e-11 42.0 0.2 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO22958.1 - 0.029 12.5 7.2 0.78 7.8 0.2 4.1 3 2 0 5 5 5 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO22958.1 - 0.082 11.6 2.1 0.73 8.5 0.6 3.0 2 1 1 3 3 3 0 Nup133 N terminal like WD40 PF00400.27 ETO22959.1 - 8.5e-60 196.6 37.2 1.5e-10 40.5 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO22959.1 - 1.3e-06 26.8 7.0 0.016 13.3 0.1 5.4 3 2 2 5 5 5 3 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO22959.1 - 3.3e-05 23.6 0.4 0.0019 17.9 0.1 3.5 1 1 3 4 4 4 1 Eukaryotic translation initiation factor eIF2A V_ATPase_I PF01496.14 ETO22959.1 - 0.9 7.3 6.4 1.2 6.8 4.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Herpes_BLRF2 PF05812.7 ETO22959.1 - 0.99 9.2 7.9 0.6 9.9 3.9 1.9 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein Gcd10p PF04189.8 ETO22961.1 - 5.1e-50 170.2 0.6 6.4e-50 169.9 0.4 1.1 1 0 0 1 1 1 1 Gcd10p family Peptidase_M24 PF00557.19 ETO22962.1 - 4.8e-34 117.7 0.0 7.1e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 ETO22962.1 - 2e-24 86.5 0.0 6.1e-18 65.5 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain HIF-1 PF11413.3 ETO22962.1 - 0.027 13.6 0.1 0.051 12.7 0.1 1.4 1 0 0 1 1 1 0 Hypoxia-inducible factor-1 GTP_cyclohydro2 PF00925.15 ETO22962.1 - 0.13 11.5 0.0 2 7.6 0.0 2.3 2 0 0 2 2 2 0 GTP cyclohydrolase II SURF1 PF02104.10 ETO22964.1 - 0.14 11.9 0.4 0.16 11.7 0.3 1.1 1 0 0 1 1 1 0 SURF1 family AAA_14 PF13173.1 ETO22965.1 - 0.0007 19.4 0.8 0.0035 17.2 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA PF00004.24 ETO22965.1 - 0.003 17.7 0.2 0.02 15.1 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETO22965.1 - 0.0054 16.4 0.1 0.12 12.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF3139 PF11337.3 ETO22965.1 - 0.048 13.9 2.4 0.097 12.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) THDPS_N_2 PF14805.1 ETO22966.1 - 0.099 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal NLE PF08154.7 ETO22967.1 - 0.004 17.1 1.2 0.073 13.0 0.1 2.9 2 0 0 2 2 2 1 NLE (NUC135) domain fn3 PF00041.16 ETO22969.1 - 0.0062 16.6 1.3 3.6 7.7 0.1 4.2 2 2 0 2 2 2 2 Fibronectin type III domain EF-hand_1 PF00036.27 ETO22970.1 - 6.3e-09 34.5 7.1 1.6e-06 26.9 0.3 2.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 ETO22970.1 - 2.9e-07 29.7 2.4 0.001 18.7 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 ETO22970.1 - 9.3e-07 28.3 3.2 1.3e-06 27.8 0.3 2.5 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 ETO22970.1 - 2e-06 27.8 2.7 4.8e-06 26.6 1.8 1.8 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 ETO22970.1 - 1.2e-05 24.4 1.5 0.00011 21.3 0.4 2.5 2 0 0 2 2 2 1 EF hand Dfp1_Him1_M PF08630.5 ETO22971.1 - 0.28 10.9 5.1 0.059 13.1 0.6 1.9 2 0 0 2 2 2 0 Dfp1/Him1, central region NUDIX PF00293.23 ETO22972.1 - 4e-07 29.7 0.0 5.8e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain eIF2A PF08662.6 ETO22973.1 - 0.062 13.0 1.8 0.37 10.4 0.4 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A CENP-B_dimeris PF09026.5 ETO22974.1 - 0.027 14.6 1.8 0.027 14.6 1.2 3.1 3 1 0 3 3 3 0 Centromere protein B dimerisation domain WD40 PF00400.27 ETO22974.1 - 0.05 13.5 0.4 13 5.8 0.1 2.8 2 0 0 2 2 2 0 WD domain, G-beta repeat Sigma70_ner PF04546.8 ETO22974.1 - 1.3 8.5 11.2 0.54 9.8 2.5 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region Sec3_C PF09763.4 ETO22975.1 - 4.7e-13 48.1 0.1 6.1e-13 47.8 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec3 Peptidase_C97 PF05903.9 ETO22976.1 - 0.0089 15.8 0.0 0.029 14.1 0.0 1.8 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 ETO22976.1 - 0.018 14.9 0.0 0.059 13.3 0.0 1.9 1 0 0 1 1 1 0 Lecithin retinol acyltransferase fn3 PF00041.16 ETO22977.1 - 3.7e-17 62.2 2.2 0.00022 21.2 0.0 5.8 5 0 0 5 5 5 5 Fibronectin type III domain PDZ PF00595.19 ETO22978.1 - 1.2e-06 28.6 0.4 1.9e-06 27.9 0.3 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 ETO22978.1 - 0.00011 22.0 0.5 0.00018 21.3 0.3 1.3 1 0 0 1 1 1 1 PDZ domain DUF3316 PF11777.3 ETO22979.1 - 0.046 13.4 0.0 0.11 12.3 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3316) DUF908 PF06012.7 ETO22979.1 - 1.3 8.2 7.5 1.6 7.9 5.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Aminotran_4 PF01063.14 ETO22980.1 - 1.1e-05 24.9 0.0 1.7e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class IV 3Beta_HSD PF01073.14 ETO22981.1 - 1.2e-14 53.6 0.1 3.1e-14 52.3 0.1 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 ETO22981.1 - 1.9e-14 54.1 0.0 4.4e-14 52.9 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 ETO22981.1 - 4.8e-13 49.0 0.0 1.9e-11 43.8 0.0 2.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 ETO22981.1 - 3.5e-10 39.5 0.0 3e-08 33.1 0.0 2.6 3 0 0 3 3 3 1 NmrA-like family adh_short PF00106.20 ETO22981.1 - 6.2e-07 29.4 0.0 1.1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETO22981.1 - 6.5e-05 22.6 0.0 0.00031 20.4 0.0 1.9 1 1 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 ETO22981.1 - 0.0078 15.2 0.0 0.014 14.3 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 ETO22981.1 - 0.13 11.1 0.0 0.36 9.7 0.0 1.7 2 0 0 2 2 2 0 Male sterility protein KAP PF05804.7 ETO22982.1 - 1.7e-73 247.7 36.9 3.3e-73 246.8 25.6 1.4 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) KAP PF05804.7 ETO22983.1 - 2.4e-09 35.7 0.1 2.7e-09 35.5 0.1 1.1 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) IF-2B PF01008.12 ETO22984.1 - 0.024 13.6 1.9 0.042 12.8 1.3 1.4 1 0 0 1 1 1 0 Initiation factor 2 subunit family IncA PF04156.9 ETO22984.1 - 0.23 11.0 12.1 0.027 14.0 4.9 2.0 2 0 0 2 2 2 0 IncA protein TPR_12 PF13424.1 ETO22987.1 - 8.8e-17 60.8 0.1 2e-16 59.6 0.0 1.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO22987.1 - 4e-08 32.7 0.5 7.1e-08 31.9 0.4 1.4 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 ETO22987.1 - 7.7e-08 31.6 0.4 7.7e-08 31.6 0.3 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO22987.1 - 2.8e-06 26.8 3.2 7.7e-06 25.4 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO22987.1 - 3e-06 26.6 0.3 1.2e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO22987.1 - 4.1e-06 26.1 8.2 5.8e-06 25.7 0.3 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETO22987.1 - 7.3e-06 25.7 0.0 1.7e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO22987.1 - 0.0048 17.0 0.5 0.02 15.0 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO22987.1 - 0.0063 16.6 2.4 0.87 9.7 0.0 2.7 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 ETO22987.1 - 0.015 15.1 0.8 0.025 14.4 0.1 1.6 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Toxin_64 PF15542.1 ETO22987.1 - 0.023 15.2 3.2 0.17 12.4 0.1 2.6 2 0 0 2 2 2 0 Putative toxin 64 Mob_Pre PF01076.14 ETO22987.1 - 0.083 12.5 0.7 0.23 11.0 0.5 1.7 1 1 0 1 1 1 0 Plasmid recombination enzyme TPR_3 PF07720.7 ETO22987.1 - 7.9 6.3 10.9 7 6.5 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Vwaint PF14624.1 ETO22988.1 - 0.19 11.8 0.3 0.19 11.8 0.2 1.7 2 0 0 2 2 2 0 VWA / Hh protein intein-like DUF3450 PF11932.3 ETO22989.1 - 1.7e-05 24.2 9.4 1.7e-05 24.2 6.5 3.2 2 1 2 4 4 4 1 Protein of unknown function (DUF3450) Baculo_PEP_C PF04513.7 ETO22989.1 - 0.0012 18.6 1.4 0.067 13.0 0.2 2.5 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.7 ETO22989.1 - 0.0041 16.8 12.2 0.0041 16.8 8.4 3.9 3 1 1 4 4 4 1 TPR/MLP1/MLP2-like protein Prefoldin_2 PF01920.15 ETO22989.1 - 0.12 12.1 0.2 0.12 12.1 0.1 5.3 3 1 2 5 5 4 0 Prefoldin subunit TMP_2 PF06791.8 ETO22989.1 - 0.15 11.6 0.1 0.15 11.6 0.0 2.2 3 0 0 3 3 3 0 Prophage tail length tape measure protein Atg14 PF10186.4 ETO22989.1 - 0.19 10.6 30.1 0.028 13.3 7.1 2.5 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2937 PF11157.3 ETO22989.1 - 0.23 10.7 1.6 2 7.7 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2937) CorA PF01544.13 ETO22989.1 - 0.99 8.3 14.0 0.35 9.8 6.9 2.0 1 1 2 3 3 3 0 CorA-like Mg2+ transporter protein FlaC_arch PF05377.6 ETO22989.1 - 1 9.3 15.9 1.3 8.9 1.1 4.3 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Fez1 PF06818.10 ETO22989.1 - 1.4 8.9 43.0 0.04 13.9 20.3 2.6 3 0 0 3 3 3 0 Fez1 DUF948 PF06103.6 ETO22989.1 - 1.6 8.6 11.4 2.6 7.9 1.8 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Phage_Gp14 PF10666.4 ETO22990.1 - 0.0019 18.0 0.2 0.0025 17.6 0.2 1.2 1 0 0 1 1 1 1 Phage protein Gp14 ORC3_N PF07034.6 ETO22990.1 - 0.0063 15.5 2.5 0.0074 15.3 1.8 1.0 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus Bac_GDH PF05088.7 ETO22990.1 - 0.0095 13.3 3.6 0.011 13.1 2.5 1.0 1 0 0 1 1 1 1 Bacterial NAD-glutamate dehydrogenase AAA_13 PF13166.1 ETO22990.1 - 0.026 13.0 8.3 0.032 12.7 5.8 1.0 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 ETO22990.1 - 0.042 12.9 5.2 0.051 12.6 3.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 MerR-DNA-bind PF09278.6 ETO22990.1 - 0.042 14.2 3.1 0.042 14.2 2.2 2.2 2 1 0 2 2 2 0 MerR, DNA binding Fungal_trans_2 PF11951.3 ETO22990.1 - 0.049 12.2 1.6 0.056 12.0 1.1 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF4407 PF14362.1 ETO22990.1 - 0.053 12.4 3.8 0.065 12.1 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LMP PF04778.7 ETO22990.1 - 0.084 12.6 5.9 0.35 10.6 4.1 1.9 1 1 0 1 1 1 0 LMP repeated region FlgN PF05130.7 ETO22990.1 - 0.11 12.7 7.7 0.15 12.2 5.3 1.4 1 1 0 1 1 1 0 FlgN protein CheY-binding PF09078.6 ETO22990.1 - 0.11 12.5 0.2 0.58 10.2 0.0 2.1 2 0 0 2 2 2 0 CheY binding Tox-ODYAM1 PF15642.1 ETO22990.1 - 0.2 10.2 3.9 0.22 10.1 2.7 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus DUF4446 PF14584.1 ETO22990.1 - 0.47 10.2 9.0 0.25 11.1 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) CorA PF01544.13 ETO22990.1 - 0.48 9.4 4.2 0.68 8.9 3.0 1.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein IncA PF04156.9 ETO22990.1 - 0.71 9.4 14.6 3 7.3 10.1 1.8 1 1 0 1 1 1 0 IncA protein ISG65-75 PF11727.3 ETO22990.1 - 0.75 8.7 5.4 0.91 8.5 3.8 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Bap31 PF05529.7 ETO22990.1 - 1.3 8.4 5.9 1.8 7.9 4.0 1.4 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF3635 PF12330.3 ETO22990.1 - 1.8 8.7 7.1 2 8.5 0.8 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF3635) DUF2203 PF09969.4 ETO22990.1 - 1.8 8.7 7.5 19 5.5 5.0 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Baculo_p24 PF05073.7 ETO22990.1 - 2.2 7.8 5.4 2.6 7.5 3.0 1.3 1 1 0 1 1 1 0 Baculovirus P24 capsid protein Metal_resist PF13801.1 ETO22990.1 - 4 7.4 8.0 2.8 7.9 2.0 2.2 2 0 0 2 2 2 0 Heavy-metal resistance CHD5 PF04420.9 ETO22990.1 - 4.5 6.9 8.4 1.7 8.2 0.6 2.3 1 1 0 2 2 2 0 CHD5-like protein DUF3829 PF12889.2 ETO22990.1 - 4.8 6.2 7.7 1 8.5 0.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3829) DUF2956 PF11169.3 ETO22990.1 - 5.3 7.0 9.3 1.5 8.7 1.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2956) DUF4409 PF14365.1 ETO22990.1 - 6.9 6.8 7.7 35 4.6 5.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4409) Iron_permease PF04120.7 ETO22990.1 - 8.1 6.0 12.5 6.6 6.3 2.1 2.7 1 1 2 3 3 3 0 Low affinity iron permease Fib_alpha PF08702.5 ETO22990.1 - 9.6 6.3 8.9 5.1 7.2 3.9 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Draxin PF15550.1 ETO22991.1 - 0.19 11.3 6.7 0.21 11.2 4.7 1.1 1 0 0 1 1 1 0 Draxin Transformer PF06495.6 ETO22991.1 - 1.2 9.0 4.9 0.26 11.1 0.8 1.7 1 1 1 2 2 2 0 Fruit fly transformer protein InvH PF04741.7 ETO22991.1 - 1.4 8.7 5.5 0.47 10.3 1.9 1.5 2 0 0 2 2 2 0 InvH outer membrane lipoprotein CD36 PF01130.16 ETO22992.1 - 1.2e-22 79.8 12.4 2.1e-22 79.0 8.6 1.3 1 1 0 1 1 1 1 CD36 family SHP PF03579.8 ETO22992.1 - 0.32 10.3 4.8 9.2 5.7 0.6 2.7 2 0 0 2 2 2 0 Small hydrophobic protein Prothymosin PF03247.9 ETO22993.1 - 0.0012 18.9 32.0 0.0029 17.7 22.2 1.7 1 0 0 1 1 1 1 Prothymosin/parathymosin family RRN3 PF05327.6 ETO22993.1 - 0.0019 16.4 6.9 0.0031 15.7 4.8 1.4 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 PBP1_TM PF14812.1 ETO22993.1 - 0.021 15.0 16.7 0.024 14.9 10.0 2.4 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Hid1 PF12722.2 ETO22993.1 - 0.03 12.0 14.4 0.052 11.2 10.0 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SprA-related PF12118.3 ETO22993.1 - 0.036 13.3 15.9 0.051 12.9 11.1 1.1 1 0 0 1 1 1 0 SprA-related family DcuC PF03606.10 ETO22993.1 - 0.045 11.9 0.4 1.4 7.0 1.6 2.0 2 0 0 2 2 2 0 C4-dicarboxylate anaerobic carrier Daxx PF03344.10 ETO22993.1 - 0.064 11.7 20.6 0.1 11.0 14.3 1.2 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 ETO22993.1 - 0.08 10.9 17.1 0.11 10.4 11.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.17 ETO22993.1 - 0.1 11.6 7.8 0.16 10.9 5.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DDHD PF02862.12 ETO22993.1 - 0.33 10.6 11.8 0.73 9.5 8.2 1.6 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 ETO22993.1 - 0.75 9.6 21.4 1.2 8.9 14.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BSMAP PF12280.3 ETO22993.1 - 1.3 8.8 5.5 2.4 7.9 3.8 1.4 1 0 0 1 1 1 0 Brain specific membrane anchored protein UPF0560 PF10577.4 ETO22993.1 - 2.4 6.3 14.5 3.4 5.8 10.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TRAP_alpha PF03896.11 ETO22993.1 - 3.3 6.6 12.8 7.1 5.5 8.8 1.6 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RNA_pol_Rpb1_5 PF04998.12 ETO22993.1 - 3.3 6.8 11.3 6.1 6.0 7.8 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF4199 PF13858.1 ETO22993.1 - 3.3 7.5 5.7 7.4 6.4 3.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) LMBR1 PF04791.11 ETO22993.1 - 4.1 5.8 8.7 5.5 5.4 6.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Pilt PF15453.1 ETO22993.1 - 4.8 6.7 13.2 6.9 6.2 9.2 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions SID-1_RNA_chan PF13965.1 ETO22993.1 - 5 5.1 7.7 8 4.4 5.3 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF3899 PF13038.1 ETO22993.1 - 7.5 6.7 8.7 1.6 8.9 2.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3899) CT47 PF15623.1 ETO22993.1 - 7.9 6.1 24.8 11 5.6 17.2 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 YjgP_YjgQ PF03739.9 ETO22994.1 - 1 8.0 3.7 1.5 7.4 2.6 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family RNA_pol_3_Rpc31 PF11705.3 ETO22995.1 - 7.6 6.3 59.1 0.78 9.6 2.6 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Sin3_corepress PF08295.7 ETO22997.1 - 1.4e-24 85.7 0.6 1.9e-24 85.3 0.4 1.1 1 0 0 1 1 1 1 Sin3 family co-repressor CDK5_activator PF03261.10 ETO22997.1 - 0.18 11.1 3.2 0.19 11.0 2.2 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF2584 PF10763.4 ETO22998.1 - 0.046 13.5 0.5 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2584) Pkinase PF00069.20 ETO22999.1 - 4.9e-05 22.6 0.3 9.4e-05 21.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain F-112 PF09645.5 ETO22999.1 - 1 9.2 4.0 1.4 8.8 2.2 1.6 2 0 0 2 2 2 0 F-112 protein G-patch_2 PF12656.2 ETO23000.1 - 0.1 12.4 3.6 0.084 12.7 0.6 2.4 1 1 1 2 2 2 0 DExH-box splicing factor binding site RasGEF PF00617.14 ETO23001.1 - 2.8e-33 115.2 1.3 2.6e-32 112.0 0.9 2.2 1 1 0 1 1 1 1 RasGEF domain WD40 PF00400.27 ETO23003.1 - 1.6e-76 249.7 15.6 3.2e-12 45.8 0.1 7.2 6 1 1 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO23003.1 - 3.8e-10 38.5 3.2 5.3e-05 21.5 0.1 3.8 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Resistin PF06954.6 ETO23003.1 - 5.6e-05 23.3 0.1 4 7.7 0.0 4.2 1 1 1 4 4 4 1 Resistin PD40 PF07676.7 ETO23003.1 - 0.00021 20.8 1.4 9.1 6.0 0.0 5.1 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO23003.1 - 0.00078 17.8 0.0 0.0059 14.9 0.0 2.1 2 0 0 2 2 2 1 Cytochrome D1 heme domain DUF1258 PF06869.7 ETO23003.1 - 0.0026 16.8 0.8 1.8 7.5 0.0 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF1258) PQQ_2 PF13360.1 ETO23003.1 - 0.0093 15.4 0.2 0.2 11.0 0.0 2.2 1 1 1 2 2 2 1 PQQ-like domain Mid2 PF04478.7 ETO23003.1 - 0.38 10.1 3.3 0.95 8.8 0.0 3.1 4 1 0 4 4 4 0 Mid2 like cell wall stress sensor UNC-93 PF05978.11 ETO23004.1 - 7.2e-08 32.0 15.4 7.2e-08 32.0 10.6 2.7 1 1 1 2 2 2 1 Ion channel regulatory protein UNC-93 DUF373 PF04123.8 ETO23004.1 - 0.21 10.6 9.3 1 8.3 6.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Transposase_22 PF02994.9 ETO23005.1 - 0.022 13.2 2.8 0.025 13.0 2.0 1.2 1 0 0 1 1 1 0 L1 transposable element Reo_sigmaC PF04582.7 ETO23005.1 - 0.024 13.8 0.1 0.057 12.6 0.0 1.6 1 1 1 2 2 2 0 Reovirus sigma C capsid protein RRF PF01765.14 ETO23005.1 - 0.03 13.7 2.1 0.044 13.2 1.4 1.1 1 0 0 1 1 1 0 Ribosome recycling factor ARD PF03079.9 ETO23005.1 - 0.041 13.8 0.9 0.051 13.5 0.6 1.2 1 0 0 1 1 1 0 ARD/ARD' family Bromodomain PF00439.20 ETO23005.1 - 0.081 12.8 2.4 0.28 11.1 0.9 2.1 1 1 1 2 2 2 0 Bromodomain DUF2361 PF10153.4 ETO23005.1 - 0.11 12.7 4.4 0.16 12.1 3.1 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) DUF1664 PF07889.7 ETO23005.1 - 0.11 12.3 1.2 0.24 11.1 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.5 ETO23005.1 - 0.15 12.1 3.7 0.25 11.4 2.6 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Snapin_Pallidin PF14712.1 ETO23005.1 - 0.44 10.8 2.9 0.7 10.2 0.3 2.1 1 1 1 2 2 2 0 Snapin/Pallidin Ras PF00071.17 ETO23006.1 - 5e-38 130.0 0.1 6.3e-38 129.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.16 ETO23006.1 - 1.7e-10 40.3 0.0 2.3e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 ETO23006.1 - 1.1e-09 38.7 0.0 2.4e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 ETO23006.1 - 5e-05 22.8 0.0 7e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Sec62 PF03839.11 ETO23006.1 - 0.044 13.1 0.6 0.069 12.5 0.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 CDC45 PF02724.9 ETO23008.1 - 0.071 11.1 15.1 0.098 10.6 10.4 1.2 1 0 0 1 1 1 0 CDC45-like protein CENP-T PF15511.1 ETO23008.1 - 0.076 12.2 10.3 0.1 11.8 7.1 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Daxx PF03344.10 ETO23008.1 - 0.093 11.1 21.0 0.12 10.8 14.6 1.1 1 0 0 1 1 1 0 Daxx Family TFIIA PF03153.8 ETO23008.1 - 0.73 9.6 24.9 1 9.2 17.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 ETO23008.1 - 0.76 7.6 29.8 0.97 7.2 20.7 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 ETO23008.1 - 1.9 7.7 27.6 2.7 7.2 19.1 1.2 1 0 0 1 1 1 0 SDA1 DUF1510 PF07423.6 ETO23008.1 - 3.7 6.8 17.9 5.3 6.3 12.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) BUD22 PF09073.5 ETO23008.1 - 5.5 5.9 24.5 7.6 5.4 17.0 1.2 1 0 0 1 1 1 0 BUD22 HSP90 PF00183.13 ETO23009.1 - 0.0037 15.7 17.1 0.0037 15.7 11.9 2.4 2 1 1 3 3 3 1 Hsp90 protein Sporozoite_P67 PF05642.6 ETO23009.1 - 5.2 4.8 15.1 0.018 12.9 4.0 1.6 2 0 0 2 2 2 0 Sporozoite P67 surface antigen PhosphMutase PF10143.4 ETO23011.1 - 0.61 9.7 6.1 0.092 12.3 0.3 2.5 2 1 0 2 2 2 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase DUF3110 PF11360.3 ETO23011.1 - 2.2 8.1 7.4 0.35 10.7 1.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3110) Reticulon PF02453.12 ETO23011.1 - 2.5 7.7 8.3 0.77 9.3 0.6 3.4 3 0 0 3 3 3 0 Reticulon WD40 PF00400.27 ETO23013.1 - 4.5e-08 32.6 4.1 0.0055 16.5 0.5 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat TPR_12 PF13424.1 ETO23014.1 - 5.5e-22 77.4 3.7 1.7e-08 34.2 0.2 3.3 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO23014.1 - 2e-15 56.1 4.3 1.2e-12 47.2 1.1 3.2 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 ETO23014.1 - 3.9e-14 51.5 12.6 1.6e-07 30.6 0.8 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO23014.1 - 2.7e-11 43.0 0.2 3.6e-05 23.5 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO23014.1 - 2.8e-11 42.3 4.1 1.8e-05 24.1 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO23014.1 - 3.8e-11 41.9 11.5 5.3e-07 28.9 0.8 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO23014.1 - 1.5e-10 40.1 11.1 1e-05 25.0 0.4 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO23014.1 - 4.6e-06 26.4 2.9 0.26 11.5 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO23014.1 - 0.00011 22.4 0.5 0.32 11.7 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO23014.1 - 0.00021 21.8 0.6 0.048 14.3 0.0 2.8 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO23014.1 - 0.0025 18.1 3.1 0.66 10.5 0.0 3.9 3 1 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 ETO23014.1 - 0.0083 15.9 0.2 0.0083 15.9 0.1 2.3 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain SNAP PF14938.1 ETO23014.1 - 0.025 13.7 2.6 0.17 11.0 0.3 2.4 2 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_19 PF14559.1 ETO23014.1 - 0.11 12.8 0.1 0.65 10.3 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 ETO23014.1 - 0.56 10.3 5.5 3.8 7.7 0.2 3.4 2 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 ETO23014.1 - 1.1 9.1 6.2 4.6 7.1 0.4 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_C14 PF00656.17 ETO23015.1 - 0.0097 15.6 0.0 0.24 11.0 0.0 2.0 2 0 0 2 2 2 2 Caspase domain SPX PF03105.14 ETO23016.1 - 6.5 6.4 36.4 11 5.7 25.2 1.3 1 0 0 1 1 1 0 SPX domain SID-1_RNA_chan PF13965.1 ETO23016.1 - 6.9 4.7 13.4 9.6 4.2 9.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF1675 PF07897.6 ETO23016.1 - 10 5.9 24.9 16 5.2 17.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) WD40 PF00400.27 ETO23017.1 - 0.00012 21.8 0.2 0.00022 20.9 0.2 1.4 1 0 0 1 1 1 1 WD domain, G-beta repeat DXP_synthase_N PF13292.1 ETO23017.1 - 0.1 11.4 0.2 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase CRAL_TRIO PF00650.15 ETO23020.1 - 1.7e-07 30.8 1.9 3.6e-07 29.7 1.3 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain DUF2465 PF10239.4 ETO23020.1 - 0.052 12.7 0.1 0.076 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2465) CRAL_TRIO PF00650.15 ETO23021.1 - 1.7e-10 40.6 0.2 2.4e-10 40.1 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain DUF2624 PF11116.3 ETO23021.1 - 0.01 16.3 0.0 1.2 9.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) RWD PF05773.17 ETO23021.1 - 0.091 12.6 0.2 0.13 12.1 0.1 1.2 1 1 0 1 1 1 0 RWD domain PilS PF08805.6 ETO23021.1 - 0.11 12.0 0.0 0.49 9.9 0.0 1.7 1 1 1 2 2 2 0 PilS N terminal GDC-P PF02347.11 ETO23021.1 - 0.15 10.7 0.0 0.22 10.1 0.0 1.3 1 1 0 1 1 1 0 Glycine cleavage system P-protein CAP_GLY PF01302.20 ETO23022.1 - 1.6e-11 43.7 0.1 3.9e-11 42.4 0.1 1.7 1 0 0 1 1 1 1 CAP-Gly domain CDC27 PF09507.5 ETO23023.1 - 0.0032 16.7 23.5 0.0037 16.5 16.3 1.2 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Herpes_DNAp_acc PF04929.7 ETO23023.1 - 0.042 12.8 6.2 0.028 13.3 2.8 1.6 1 1 0 1 1 1 0 Herpes DNA replication accessory factor Presenilin PF01080.12 ETO23023.1 - 1 8.0 13.1 1.6 7.4 9.1 1.2 1 0 0 1 1 1 0 Presenilin TFIIF_alpha PF05793.7 ETO23023.1 - 5.1 5.3 26.9 7.9 4.7 18.6 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Daxx PF03344.10 ETO23023.1 - 6.8 5.0 29.7 12 4.2 20.6 1.4 1 0 0 1 1 1 0 Daxx Family MOZ_SAS PF01853.13 ETO23024.1 - 1.5e-49 167.7 7.0 6.4e-47 159.2 5.6 3.3 1 1 1 2 2 2 2 MOZ/SAS family Tudor-knot PF11717.3 ETO23024.1 - 1.6e-08 34.1 0.1 5.3e-08 32.4 0.0 1.9 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Not1 PF04054.10 ETO23025.1 - 5.7e-91 305.2 6.7 9.2e-91 304.5 4.7 1.3 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 ETO23026.1 - 1e-25 90.1 4.2 1e-25 90.1 2.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) ASFV_J13L PF05568.6 ETO23027.1 - 0.0019 17.7 0.2 0.0019 17.7 0.1 2.3 3 0 0 3 3 3 1 African swine fever virus J13L protein DUF3278 PF11683.3 ETO23027.1 - 0.011 15.6 0.5 0.033 14.1 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) DUF929 PF06053.6 ETO23027.1 - 0.042 12.9 2.7 0.1 11.6 1.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF929) Tetraspannin PF00335.15 ETO23027.1 - 0.057 12.6 0.1 0.13 11.4 0.1 1.7 1 1 0 1 1 1 0 Tetraspanin family DUF2208 PF09973.4 ETO23027.1 - 0.86 8.7 6.9 0.56 9.4 3.0 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2208) Chordopox_G3 PF06129.7 ETO23027.1 - 7.1 6.8 8.4 1.8 8.7 2.6 2.5 2 1 0 2 2 2 0 Chordopoxvirus G3 protein PPC PF04151.10 ETO23028.1 - 0.27 12.2 7.4 0.69 10.9 5.1 1.7 1 0 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain DUF3714 PF12508.3 ETO23029.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3714) RRM_1 PF00076.17 ETO23030.1 - 5.6e-21 73.9 0.0 1.5e-13 50.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO23030.1 - 1.3e-13 50.6 0.0 2.8e-08 33.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO23030.1 - 2.1e-08 33.8 0.6 0.0012 18.6 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 ETO23030.1 - 0.0042 17.0 0.0 0.25 11.3 0.0 2.4 2 0 0 2 2 2 1 RNA binding domain SpoU_methylase PF00588.14 ETO23032.1 - 8.6e-06 25.6 0.3 7.6 6.4 0.0 4.5 4 0 0 4 4 4 4 SpoU rRNA Methylase family zf-H2C2_2 PF13465.1 ETO23036.1 - 4.9e-09 36.0 28.2 1.4e-05 25.1 0.6 5.4 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 ETO23036.1 - 8.9e-07 28.9 27.9 0.095 13.0 0.1 5.3 4 1 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETO23036.1 - 7.5e-05 22.7 26.6 0.66 10.4 2.7 5.4 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 ETO23036.1 - 0.0033 17.5 20.2 0.086 13.0 0.1 5.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 ETO23036.1 - 0.0046 16.8 29.3 0.033 14.1 2.7 4.6 5 0 0 5 5 5 3 C2H2-type zinc finger zf-met PF12874.2 ETO23036.1 - 0.15 12.3 19.8 5.3 7.4 0.5 5.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Zn_Tnp_IS1595 PF12760.2 ETO23036.1 - 8.7 6.2 17.8 1 9.1 0.3 4.0 3 1 0 3 3 3 0 Transposase zinc-ribbon domain Glycos_transf_1 PF00534.15 ETO23037.1 - 4.3e-20 71.8 0.0 8.7e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 ETO23037.1 - 0.00018 21.7 0.0 0.00033 20.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Voltage_CLC PF00654.15 ETO23037.1 - 0.015 14.3 0.0 0.029 13.4 0.0 1.5 1 0 0 1 1 1 0 Voltage gated chloride channel MMPL PF03176.10 ETO23039.1 - 3.4e-35 121.3 8.3 4.2e-34 117.7 5.7 2.0 1 1 0 1 1 1 1 MMPL family TPR_12 PF13424.1 ETO23040.1 - 3.2e-69 228.8 16.7 1.1e-18 66.9 0.1 4.8 2 1 4 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETO23040.1 - 7.6e-34 113.9 29.8 2e-08 33.4 0.1 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETO23040.1 - 1.8e-32 110.7 8.3 9e-11 41.2 0.1 4.9 4 1 0 4 4 4 4 TPR repeat TPR_7 PF13176.1 ETO23040.1 - 5.8e-29 97.5 3.2 4.4e-07 29.1 0.0 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETO23040.1 - 1.2e-28 96.6 17.5 1.6e-06 27.5 0.0 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 ETO23040.1 - 1.1e-25 87.4 29.1 5.2e-07 28.9 0.1 7.4 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETO23040.1 - 8.8e-25 85.8 0.0 9.5e-07 28.5 0.0 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETO23040.1 - 1.1e-13 50.1 11.8 0.026 14.7 0.0 8.2 8 2 0 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO23040.1 - 2.2e-09 37.1 1.9 0.089 13.2 0.0 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO23040.1 - 6.2e-09 35.7 0.0 0.036 14.6 0.0 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat SNAP PF14938.1 ETO23040.1 - 9.3e-08 31.5 4.3 4.9e-07 29.1 0.3 2.9 2 1 1 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_16 PF13432.1 ETO23040.1 - 1.4e-05 25.5 0.0 0.63 10.7 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat MIT PF04212.13 ETO23040.1 - 2.7e-05 23.9 9.5 0.038 13.8 0.0 5.1 4 1 1 5 5 5 2 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.4 ETO23040.1 - 4.6e-05 22.5 0.1 0.34 10.2 0.0 3.8 3 1 0 3 3 3 2 SHNi-TPR DUF2225 PF09986.4 ETO23040.1 - 7.9e-05 22.2 7.4 0.079 12.4 0.1 3.9 1 1 2 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) RPN7 PF10602.4 ETO23040.1 - 0.00056 19.3 3.2 0.54 9.6 0.3 3.6 1 1 1 3 3 3 2 26S proteasome subunit RPN7 TPR_19 PF14559.1 ETO23040.1 - 0.0043 17.3 0.6 0.99 9.7 0.0 3.3 3 1 1 4 4 3 1 Tetratricopeptide repeat CathepsinC_exc PF08773.6 ETO23040.1 - 0.0093 16.1 1.4 0.19 11.9 0.0 3.3 1 1 2 3 3 3 1 Cathepsin C exclusion domain Apc3 PF12895.2 ETO23040.1 - 0.023 14.8 11.7 0.034 14.2 0.2 3.8 3 2 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.2 ETO23040.1 - 0.051 13.4 0.2 1.2 8.9 0.0 3.0 4 0 0 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_5 PF12688.2 ETO23040.1 - 0.15 12.0 0.1 62 3.6 0.0 3.4 3 1 1 4 4 3 0 Tetratrico peptide repeat PPR PF01535.15 ETO23040.1 - 0.61 10.1 8.1 6.5 6.9 0.0 5.4 7 0 0 7 7 5 0 PPR repeat NSF PF02071.15 ETO23040.1 - 7.2 7.6 10.9 1.2e+02 4.0 0.0 6.7 6 1 0 7 7 6 0 Aromatic-di-Alanine (AdAR) repeat DUF4471 PF14740.1 ETO23041.1 - 0.019 14.2 4.1 0.021 14.0 2.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) Tombus_P33 PF08500.5 ETO23041.1 - 0.16 11.6 1.3 0.22 11.2 0.9 1.1 1 0 0 1 1 1 0 Tombusvirus p33 ETRAMP PF09716.5 ETO23044.1 - 0.13 12.2 3.6 0.4 10.6 0.2 2.8 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Kelch_6 PF13964.1 ETO23045.1 - 4.5e-08 32.9 6.1 0.004 17.2 0.5 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO23045.1 - 3.4e-05 23.2 9.6 0.03 13.8 0.9 4.5 4 1 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO23045.1 - 0.0002 20.9 4.6 1.7 8.5 0.0 4.1 2 1 1 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETO23045.1 - 0.00046 19.8 3.8 0.14 11.9 0.2 3.6 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO23045.1 - 0.0011 19.0 0.4 0.014 15.5 0.0 2.7 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO23045.1 - 0.018 15.0 0.5 1.8 8.6 0.1 3.2 3 0 0 3 3 3 0 Kelch motif AAA_11 PF13086.1 ETO23046.1 - 0.097 12.2 1.7 0.17 11.4 1.2 1.4 1 0 0 1 1 1 0 AAA domain FLO_LFY PF01698.11 ETO23046.1 - 0.2 10.4 5.1 0.26 10.0 3.6 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF1168 PF06658.7 ETO23046.1 - 0.59 9.6 20.6 0.78 9.2 14.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) SR-25 PF10500.4 ETO23046.1 - 0.77 9.1 19.2 0.94 8.9 13.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CMS1 PF14617.1 ETO23046.1 - 1.1 8.3 7.8 1.3 8.0 5.4 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit BLVR PF06375.6 ETO23046.1 - 1.2 8.9 16.3 1.7 8.4 11.3 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) TMEM154 PF15102.1 ETO23046.1 - 8.5 6.0 6.8 14 5.4 4.7 1.3 1 0 0 1 1 1 0 TMEM154 protein family C2 PF00168.25 ETO23048.1 - 5.4e-15 55.0 0.0 1.3e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 C2 domain zf-RING_2 PF13639.1 ETO23050.1 - 2.4e-12 46.4 3.6 7.3e-12 44.9 2.5 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 ETO23050.1 - 6.3e-07 29.4 3.8 9.9e-07 28.7 1.1 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 ETO23050.1 - 2.6e-06 26.9 1.2 5.1e-06 26.0 0.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO23050.1 - 3e-06 26.8 2.3 7.1e-06 25.6 1.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 ETO23050.1 - 6.6e-06 25.6 2.2 1.6e-05 24.4 1.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO23050.1 - 7.6e-06 25.8 3.4 1.7e-05 24.7 2.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 ETO23050.1 - 0.015 15.1 0.8 0.015 15.1 0.6 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger CENP-B_dimeris PF09026.5 ETO23050.1 - 0.1 12.8 16.6 0.1 12.8 5.0 2.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RINGv PF12906.2 ETO23050.1 - 0.27 11.3 2.3 0.82 9.7 1.6 1.8 1 0 0 1 1 1 0 RING-variant domain FAM176 PF14851.1 ETO23050.1 - 5.1 6.7 14.4 1.1 8.9 2.2 2.6 2 0 0 2 2 2 0 FAM176 family DUF4611 PF15387.1 ETO23051.1 - 6.2 7.0 14.5 14 5.9 9.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) Hyccin PF09790.4 ETO23052.1 - 3.4e-16 58.9 0.5 5.6e-07 28.7 0.0 2.5 2 0 0 2 2 2 2 Hyccin ATP-synt_8 PF00895.15 ETO23052.1 - 0.78 9.9 4.5 7.4 6.8 1.8 3.4 2 0 0 2 2 2 0 ATP synthase protein 8 WBP-1 PF11669.3 ETO23052.1 - 1.4 9.0 6.7 5.2 7.2 0.5 3.3 2 1 2 4 4 4 0 WW domain-binding protein 1 EcsB PF05975.7 ETO23052.1 - 1.4 7.2 7.7 0.36 9.2 1.9 2.0 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB Rab5ip PF07019.7 ETO23052.1 - 2.2 8.4 5.5 5.3 7.2 2.1 2.4 2 0 0 2 2 2 0 Rab5-interacting protein (Rab5ip) COX2_TM PF02790.10 ETO23052.1 - 4 7.4 5.9 0.57 10.1 0.3 2.5 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain YajC PF02699.10 ETO23052.1 - 9 6.0 6.9 11 5.7 1.4 2.5 2 0 0 2 2 2 0 Preprotein translocase subunit NUDIX_4 PF14815.1 ETO23053.1 - 0.031 13.6 0.2 0.55 9.6 0.0 2.8 2 0 0 2 2 2 0 NUDIX domain Adap_comp_sub PF00928.16 ETO23054.1 - 7.8e-58 195.6 0.1 8.7e-58 195.4 0.0 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Adap_comp_sub PF00928.16 ETO23055.1 - 2e-05 23.8 0.1 2.9e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Amnionless PF14828.1 ETO23055.1 - 0.015 13.8 0.1 0.017 13.6 0.1 1.1 1 0 0 1 1 1 0 Amnionless DUF4446 PF14584.1 ETO23055.1 - 0.017 14.9 0.7 0.03 14.1 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF2207 PF09972.4 ETO23055.1 - 0.072 11.6 1.9 0.087 11.3 1.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TMEM156 PF15106.1 ETO23055.1 - 0.21 10.7 9.1 0.3 10.2 6.3 1.2 1 0 0 1 1 1 0 TMEM156 protein family Shisa PF13908.1 ETO23055.1 - 0.23 11.6 6.1 0.35 11.0 4.2 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator HemY_N PF07219.8 ETO23055.1 - 0.25 10.8 6.3 0.21 11.1 3.4 1.6 1 1 0 1 1 1 0 HemY protein N-terminus DUF3810 PF12725.2 ETO23055.1 - 0.33 9.7 3.2 0.45 9.3 2.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) EphA2_TM PF14575.1 ETO23055.1 - 2 8.8 6.5 5.1 7.5 4.5 1.8 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SHP PF03579.8 ETO23055.1 - 3.6 7.0 15.9 1.4 8.2 9.0 1.8 1 1 1 2 2 2 0 Small hydrophobic protein Rifin_STEVOR PF02009.11 ETO23055.1 - 6.7 6.2 12.5 10 5.6 8.7 1.4 1 0 0 1 1 1 0 Rifin/stevor family MIP-T3 PF10243.4 ETO23056.1 - 0.015 13.8 19.8 0.022 13.2 13.7 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Sucrose_synth PF00862.14 ETO23056.1 - 0.073 11.0 0.0 0.096 10.6 0.0 1.1 1 0 0 1 1 1 0 Sucrose synthase Hid1 PF12722.2 ETO23056.1 - 0.085 10.5 10.7 0.09 10.4 7.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SprA-related PF12118.3 ETO23056.1 - 1 8.6 19.4 0.33 10.2 11.4 1.5 2 0 0 2 2 2 0 SprA-related family SDA1 PF05285.7 ETO23056.1 - 1.4 8.1 31.6 0.12 11.6 18.2 1.7 2 0 0 2 2 2 0 SDA1 Cwf_Cwc_15 PF04889.7 ETO23056.1 - 4.1 7.0 35.7 0.73 9.4 21.6 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Trypan_PARP PF05887.6 ETO23056.1 - 5.7 6.7 8.8 8.5 6.1 6.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Vfa1 PF08432.5 ETO23056.1 - 8.5 6.3 20.1 6.1 6.8 12.3 1.8 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 TRM13 PF05206.9 ETO23057.1 - 0.028 13.6 0.4 0.045 12.9 0.3 1.3 1 0 0 1 1 1 0 Methyltransferase TRM13 DUF2550 PF10739.4 ETO23057.1 - 0.14 12.0 1.6 1.3 9.0 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2550) NPCC PF08058.6 ETO23057.1 - 0.25 11.1 2.7 1.2 8.9 0.2 2.1 2 0 0 2 2 2 0 Nuclear pore complex component ALS2CR8 PF15299.1 ETO23057.1 - 1.8 8.1 6.8 2.7 7.5 4.7 1.4 1 1 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 SART-1 PF03343.8 ETO23058.1 - 0.0084 14.5 5.8 0.0095 14.3 4.0 1.1 1 0 0 1 1 1 1 SART-1 family PX PF00787.19 ETO23059.1 - 3.6e-15 55.7 6.4 1.7e-13 50.3 0.2 3.0 2 1 1 3 3 3 2 PX domain DUF999 PF06198.6 ETO23059.1 - 0.0071 16.1 0.6 0.016 14.9 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF999) Mito_fiss_reg PF05308.6 ETO23059.1 - 0.0077 15.6 2.9 0.011 15.0 2.0 1.2 1 0 0 1 1 1 1 Mitochondrial fission regulator WD40 PF00400.27 ETO23061.1 - 0.00038 20.2 0.0 0.13 12.1 0.0 3.0 2 1 0 2 2 2 2 WD domain, G-beta repeat RasGEF PF00617.14 ETO23062.1 - 4e-38 131.0 0.8 1e-37 129.7 0.5 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 ETO23062.1 - 1.5e-10 41.0 0.1 1.5e-10 41.0 0.1 3.2 3 0 0 3 3 3 1 RasGEF N-terminal motif ABC_tran PF00005.22 ETO23063.1 - 2.6e-35 121.7 0.0 4e-27 95.1 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 ETO23063.1 - 1.5e-29 103.1 8.9 1.5e-29 103.1 6.2 1.7 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.1 ETO23063.1 - 1.5e-16 61.2 0.0 1.4e-05 25.1 0.0 3.9 2 1 1 3 3 3 3 AAA domain SbcCD_C PF13558.1 ETO23063.1 - 0.0091 15.8 0.0 7.1 6.6 0.0 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 ETO23063.1 - 0.42 10.8 0.0 0.42 10.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain WD40 PF00400.27 ETO23064.1 - 2.1e-05 24.1 0.7 8.4e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 WD domain, G-beta repeat Metallophos_C PF14008.1 ETO23065.1 - 1.5e-17 63.4 0.0 2.4e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.23 ETO23065.1 - 8.3e-07 28.5 0.3 1.6e-06 27.6 0.1 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 ETO23065.1 - 0.11 12.3 0.0 0.29 10.9 0.0 1.8 2 1 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain fn3 PF00041.16 ETO23066.1 - 0.0016 18.5 0.1 0.44 10.7 0.0 2.6 2 0 0 2 2 2 2 Fibronectin type III domain PA14 PF07691.7 ETO23066.1 - 0.039 13.6 1.2 0.28 10.8 0.8 2.5 2 1 0 2 2 2 0 PA14 domain WD40 PF00400.27 ETO23069.1 - 2.8e-30 103.0 14.6 1.4e-11 43.7 0.1 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO23069.1 - 1.3e-09 36.8 0.7 4.2e-05 21.8 0.0 2.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Glyphos_transf PF04464.9 ETO23069.1 - 0.0029 16.4 0.3 0.0031 16.3 0.2 1.0 1 0 0 1 1 1 1 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase DUF2298 PF10060.4 ETO23070.1 - 0.0047 15.8 0.6 0.0074 15.1 0.4 1.3 1 0 0 1 1 1 1 Uncharacterized membrane protein (DUF2298) DUF4293 PF14126.1 ETO23070.1 - 0.073 12.9 1.5 0.17 11.8 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) PhoD PF09423.5 ETO23070.1 - 0.12 10.9 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 PhoD-like phosphatase Polysacc_synt PF01943.12 ETO23070.1 - 1.1 8.5 6.3 0.1 11.8 0.4 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Baculo_PEP_C PF04513.7 ETO23071.1 - 0.023 14.5 0.1 0.023 14.5 0.1 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus WXG100 PF06013.7 ETO23071.1 - 0.051 13.5 5.0 5.5 7.0 1.6 3.2 1 1 1 2 2 2 0 Proteins of 100 residues with WXG PilJ PF13675.1 ETO23071.1 - 0.14 12.4 2.9 0.32 11.3 2.0 1.5 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Raptor_N PF14538.1 ETO23071.1 - 0.44 10.3 6.6 0.12 12.2 0.5 2.1 1 1 1 2 2 2 0 Raptor N-terminal CASPase like domain GvpK PF05121.7 ETO23071.1 - 0.82 9.5 4.4 2 8.2 0.0 2.9 2 1 1 3 3 3 0 Gas vesicle protein K Allexi_40kDa PF05549.6 ETO23071.1 - 1.6 7.9 8.5 0.19 11.0 0.5 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein TrbI_Ftype PF09677.5 ETO23071.1 - 3.5 7.4 6.1 0.64 9.8 0.6 2.2 2 0 0 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) UCH PF00443.24 ETO23071.1 - 5.3 6.0 10.1 0.15 11.0 2.2 1.8 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Ferritin-like PF12902.2 ETO23071.1 - 6.1 6.3 9.8 0.45 10.0 2.2 2.3 2 1 0 2 2 2 0 Ferritin-like ubiquitin PF00240.18 ETO23072.1 - 7e-20 70.2 0.2 2.6e-19 68.3 0.1 2.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 ETO23072.1 - 2.9e-10 39.6 0.5 7.8e-10 38.3 0.3 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 ETO23072.1 - 0.032 14.4 0.5 0.12 12.6 0.1 2.3 3 0 0 3 3 3 0 Ubiquitin-like domain SR-25 PF10500.4 ETO23074.1 - 0.3 10.5 2.0 0.32 10.4 1.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RHD3 PF05879.7 ETO23075.1 - 3.4e-45 154.2 3.6 3.8e-45 154.0 2.5 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) DUF2262 PF10020.4 ETO23075.1 - 0.025 14.7 0.3 0.075 13.2 0.2 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2262) DUF3284 PF11687.3 ETO23075.1 - 0.059 13.1 0.0 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3284) PRESAN PF09687.5 ETO23075.1 - 0.29 11.2 8.1 0.5 10.4 0.6 3.3 2 1 0 2 2 2 0 Plasmodium RESA N-terminal Mucin PF01456.12 ETO23076.1 - 0.00023 20.9 31.2 0.014 15.2 15.6 2.2 2 0 0 2 2 2 2 Mucin-like glycoprotein Trp_oprn_chp PF09534.5 ETO23076.1 - 0.017 14.7 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Glyco_transf_49 PF13896.1 ETO23076.1 - 0.07 12.2 0.1 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl-transferase for dystroglycan Herpes_UL74 PF07982.7 ETO23076.1 - 7 5.2 11.9 0.073 11.7 2.6 1.7 2 0 0 2 2 2 0 Herpes UL74 glycoproteins SSP160 PF06933.6 ETO23076.1 - 9.3 4.0 28.7 0.67 7.8 1.4 2.1 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Kelch_1 PF01344.20 ETO23077.1 - 0.0029 17.1 0.0 0.0069 15.9 0.0 1.6 1 0 0 1 1 1 1 Kelch motif Kelch_4 PF13418.1 ETO23077.1 - 0.034 13.9 0.0 0.09 12.5 0.0 1.7 1 0 0 1 1 1 0 Galactose oxidase, central domain Corona_nucleoca PF00937.13 ETO23077.1 - 0.19 10.6 22.0 0.35 9.7 15.2 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein WBP-1 PF11669.3 ETO23077.1 - 0.82 9.7 2.6 1.1 9.3 0.0 2.5 2 1 1 3 3 3 0 WW domain-binding protein 1 PRP3 PF08572.5 ETO23078.1 - 7.4e-27 94.1 4.4 1.9e-26 92.8 3.1 1.7 1 1 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) Arm PF00514.18 ETO23079.1 - 2.9e-09 36.4 0.4 0.011 15.5 0.0 3.9 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 ETO23079.1 - 0.00029 21.2 0.0 0.16 12.5 0.0 2.9 3 0 0 3 3 3 2 HEAT-like repeat HEAT_2 PF13646.1 ETO23079.1 - 0.00044 20.4 0.0 0.63 10.3 0.0 2.2 2 0 0 2 2 2 2 HEAT repeats Sec23_trunk PF04811.10 ETO23082.1 - 6.8e-37 127.1 0.7 6.6e-20 71.5 0.0 4.3 3 1 1 4 4 4 4 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 ETO23082.1 - 9.3e-16 57.1 0.0 2.2e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 ETO23082.1 - 2.7e-14 52.4 7.6 6.1e-14 51.2 5.3 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 ETO23082.1 - 3.7e-11 43.3 0.0 1.1e-10 41.8 0.0 1.9 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Inhibitor_I71 PF12628.2 ETO23082.1 - 0.018 14.7 1.1 0.018 14.7 0.8 2.1 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor CAP_GLY PF01302.20 ETO23083.1 - 2.5e-05 23.9 0.1 5.4e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 CAP-Gly domain 2OG-FeII_Oxy_3 PF13640.1 ETO23084.1 - 4.1e-08 33.6 0.0 9.7e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sigma70_ner PF04546.8 ETO23085.1 - 0.071 12.7 2.5 0.1 12.1 1.7 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CK_II_beta PF01214.13 ETO23086.1 - 4.9e-52 176.1 4.4 4.5e-28 98.0 0.0 2.2 1 1 0 2 2 2 2 Casein kinase II regulatory subunit DEAD PF00270.24 ETO23087.1 - 9.3e-41 139.1 1.8 2.2e-40 137.9 0.6 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETO23087.1 - 1.9e-29 101.2 0.1 5.3e-29 99.9 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SAM_PNT PF02198.11 ETO23087.1 - 0.0002 21.0 0.1 0.00047 19.8 0.1 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain AAA_22 PF13401.1 ETO23087.1 - 0.0005 20.2 0.2 0.0039 17.3 0.1 2.5 2 1 0 2 2 2 1 AAA domain Helicase_RecD PF05127.9 ETO23087.1 - 0.012 15.2 0.0 0.032 13.8 0.0 1.7 1 0 0 1 1 1 0 Helicase AAA_30 PF13604.1 ETO23087.1 - 0.015 14.8 0.1 0.039 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 ETO23087.1 - 0.026 14.2 0.4 0.092 12.5 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain Helicase_C_2 PF13307.1 ETO23087.1 - 0.031 14.2 0.0 0.093 12.6 0.0 1.8 1 0 0 1 1 1 0 Helicase C-terminal domain SAM_1 PF00536.25 ETO23087.1 - 0.21 11.7 1.5 0.45 10.7 0.5 2.1 2 1 0 2 2 2 0 SAM domain (Sterile alpha motif) IQ PF00612.22 ETO23088.1 - 0.0016 17.9 0.9 0.0037 16.7 0.6 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF1492 PF07374.6 ETO23088.1 - 0.85 9.7 8.6 0.13 12.3 1.4 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1492) A2M_recep PF07677.9 ETO23088.1 - 0.95 9.6 4.5 0.83 9.8 1.7 1.9 1 1 0 1 1 1 0 A-macroglobulin receptor Ead_Ea22 PF13935.1 ETO23088.1 - 3.2 8.0 11.8 0.54 10.5 1.8 2.5 1 1 1 2 2 2 0 Ead/Ea22-like protein GTPase_Cys_C PF12631.2 ETO23088.1 - 4.7 7.6 7.7 36 4.8 2.1 2.7 1 1 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE DUF1823 PF08853.6 ETO23089.1 - 0.042 13.5 0.2 0.062 13.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1823) Med3 PF11593.3 ETO23090.1 - 0.019 14.2 11.4 0.019 14.2 7.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Spt20 PF12090.3 ETO23090.1 - 0.059 12.7 4.5 0.056 12.8 3.1 1.2 1 0 0 1 1 1 0 Spt20 family Med15 PF09606.5 ETO23090.1 - 0.093 10.9 21.9 0.096 10.8 15.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal ABC2_membrane_3 PF12698.2 ETO23090.1 - 0.25 10.3 1.3 0.28 10.1 0.9 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein Suf PF05843.9 ETO23090.1 - 0.26 10.9 6.3 0.26 10.9 4.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) G0-G1_switch_2 PF15103.1 ETO23090.1 - 2.2 8.5 6.7 0.3 11.3 1.3 1.8 2 0 0 2 2 2 0 G0/G1 switch protein 2 DUF4199 PF13858.1 ETO23090.1 - 3.6 7.4 6.0 5.1 7.0 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF3154 PF11351.3 ETO23090.1 - 9.6 5.9 6.9 15 5.3 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) Ras PF00071.17 ETO23091.1 - 4.4e-48 162.7 1.1 5.9e-48 162.3 0.7 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO23091.1 - 6.6e-16 58.8 0.5 1.3e-15 57.9 0.1 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO23091.1 - 3.5e-14 52.4 0.2 4.8e-14 51.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETO23091.1 - 4.7e-08 32.4 1.1 6.8e-08 31.9 0.8 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 ETO23091.1 - 0.00017 21.7 0.0 0.0003 20.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 ETO23091.1 - 0.0024 17.7 0.2 0.0047 16.8 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 ETO23091.1 - 0.0046 16.9 0.1 0.013 15.4 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 ETO23091.1 - 0.0059 16.3 0.3 0.023 14.3 0.0 1.9 2 1 0 2 2 2 1 Archaeal ATPase AAA_24 PF13479.1 ETO23091.1 - 0.017 14.6 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 ETO23091.1 - 0.018 14.0 0.0 0.039 12.9 0.0 1.6 2 0 0 2 2 2 0 Septin DUF258 PF03193.11 ETO23091.1 - 0.022 13.9 0.0 0.038 13.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 NACHT PF05729.7 ETO23091.1 - 0.042 13.5 0.1 0.081 12.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain cobW PF02492.14 ETO23091.1 - 0.048 13.0 1.0 0.22 10.9 0.2 2.1 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF1240 PF06836.7 ETO23092.1 - 0.57 10.4 9.6 2 8.6 6.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1240) Pmp3 PF01679.12 ETO23092.1 - 0.65 9.7 4.4 0.78 9.4 1.7 2.0 2 0 0 2 2 2 0 Proteolipid membrane potential modulator Sulfotransfer_2 PF03567.9 ETO23093.1 - 2.5e-06 27.3 0.9 5.9e-06 26.1 0.6 1.6 1 0 0 1 1 1 1 Sulfotransferase family Flavodoxin_5 PF12724.2 ETO23094.1 - 0.0096 15.9 0.4 0.034 14.1 0.3 1.9 1 0 0 1 1 1 1 Flavodoxin domain Reo_sigmaC PF04582.7 ETO23094.1 - 2.3 7.2 6.8 0.23 10.5 0.8 2.0 1 1 2 3 3 3 0 Reovirus sigma C capsid protein zf-RING_2 PF13639.1 ETO23095.1 - 4.6e-06 26.3 7.8 1.7e-05 24.5 5.6 1.9 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO23095.1 - 1.7e-05 24.7 8.6 7.8e-05 22.6 6.4 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 ETO23095.1 - 7.3e-05 22.4 6.8 0.00023 20.8 4.7 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 ETO23095.1 - 0.0016 18.0 7.1 0.0055 16.3 5.0 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO23095.1 - 0.0044 16.7 10.0 0.055 13.1 7.4 2.2 1 1 1 2 2 2 1 zinc-RING finger domain Strabismus PF06638.6 ETO23095.1 - 0.022 13.1 0.0 0.022 13.1 0.0 1.1 1 0 0 1 1 1 0 Strabismus protein DUF3328 PF11807.3 ETO23095.1 - 0.076 12.6 1.4 0.098 12.3 0.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) zf-C3HC4_4 PF15227.1 ETO23095.1 - 0.093 12.6 9.3 0.37 10.6 6.4 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 ETO23095.1 - 0.35 10.6 7.1 1.7 8.5 4.9 2.0 1 1 1 2 2 2 0 zf-RING of BARD1-type protein Fer2 PF00111.22 ETO23095.1 - 3 7.6 6.2 0.28 10.9 0.9 1.9 2 1 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain FAM176 PF14851.1 ETO23096.1 - 1.2e-05 25.0 2.1 0.00032 20.3 0.0 2.5 3 0 0 3 3 3 2 FAM176 family DUF4611 PF15387.1 ETO23096.1 - 0.059 13.5 0.8 0.059 13.5 0.5 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) WD40 PF00400.27 ETO23097.1 - 1.2e-05 25.0 0.8 4.6e-05 23.1 0.1 2.3 2 1 0 2 2 2 1 WD domain, G-beta repeat CRT10 PF08728.5 ETO23097.1 - 0.025 12.6 0.5 0.1 10.5 0.0 2.1 3 0 0 3 3 3 0 CRT10 RRM_1 PF00076.17 ETO23099.1 - 0.043 13.4 0.0 1.5 8.5 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phage_holin_1 PF04531.8 ETO23099.1 - 0.13 12.3 0.2 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Bacteriophage holin Tubulin PF00091.20 ETO23100.1 - 4e-37 128.1 1.0 1.5e-36 126.2 0.7 1.7 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tim54 PF11711.3 ETO23100.1 - 0.0035 15.9 0.7 0.0044 15.6 0.5 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 VRP3 PF03536.10 ETO23101.1 - 0.039 13.1 0.6 0.14 11.2 0.1 1.9 2 0 0 2 2 2 0 Salmonella virulence-associated 28kDa protein Opiods_neuropep PF01160.13 ETO23101.1 - 0.097 12.4 0.7 0.28 10.9 0.5 1.8 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide Phage_Gp23 PF10669.4 ETO23102.1 - 0.0084 16.2 3.2 0.0084 16.2 2.2 1.6 2 0 0 2 2 2 1 Protein gp23 (Bacteriophage A118) ATP-synt_S1 PF05827.7 ETO23102.1 - 0.02 14.2 0.1 0.024 13.9 0.1 1.1 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) Orthoreo_P10 PF07204.6 ETO23102.1 - 0.042 13.5 0.9 0.081 12.6 0.3 1.7 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 Shisa PF13908.1 ETO23102.1 - 0.046 13.8 1.7 0.084 13.0 1.2 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator PetG PF02529.10 ETO23103.1 - 0.15 11.6 2.3 0.2 11.2 0.1 2.2 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 ABC_membrane PF00664.18 ETO23105.1 - 7.5e-09 35.3 8.4 1.3e-08 34.6 5.4 1.7 1 1 0 1 1 1 1 ABC transporter transmembrane region zf-C2H2_4 PF13894.1 ETO23106.1 - 2.7e-06 27.3 21.4 0.0048 17.1 0.1 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 ETO23106.1 - 1.7e-05 24.8 22.5 0.35 11.2 0.1 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type Transpos_assoc PF13963.1 ETO23106.1 - 0.0054 16.7 5.6 0.072 13.0 0.0 3.4 3 0 0 3 3 3 1 Transposase-associated domain IBR PF01485.16 ETO23106.1 - 0.01 15.6 1.0 0.38 10.6 0.1 2.8 2 0 0 2 2 2 0 IBR domain DUF3449 PF11931.3 ETO23106.1 - 2 7.8 11.9 0.23 10.9 4.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) DUF3464 PF11947.3 ETO23106.1 - 4.3 6.7 6.4 39 3.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) DUF3366 PF11846.3 ETO23107.1 - 0.0033 17.3 0.5 0.0053 16.6 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3366) Dynamitin PF04912.9 ETO23108.1 - 1.1e-28 100.1 7.7 2.7e-28 98.8 5.3 1.5 1 1 0 1 1 1 1 Dynamitin DUF2357 PF09823.4 ETO23108.1 - 0.0066 15.5 3.7 0.14 11.2 0.2 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF2357) DUF2721 PF11026.3 ETO23108.1 - 0.016 14.8 2.3 3.7 7.2 0.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) Ran-binding PF05508.6 ETO23108.1 - 0.017 14.0 1.1 0.035 12.9 0.1 1.9 2 0 0 2 2 2 0 RanGTP-binding protein Occludin_ELL PF07303.8 ETO23108.1 - 0.017 15.8 4.6 0.92 10.2 0.7 2.6 2 1 0 2 2 2 0 Occludin homology domain DASH_Dad3 PF08656.5 ETO23108.1 - 0.025 14.2 0.2 0.025 14.2 0.1 2.6 3 1 0 3 3 2 0 DASH complex subunit Dad3 PilJ PF13675.1 ETO23108.1 - 0.044 14.0 4.1 2.8 8.2 0.1 3.2 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DivIC PF04977.10 ETO23108.1 - 0.17 11.4 4.0 2.3 7.7 0.2 2.7 2 0 0 2 2 2 0 Septum formation initiator Prominin PF05478.6 ETO23108.1 - 0.24 8.8 3.1 2 5.8 0.1 2.3 2 1 0 2 2 2 0 Prominin Spectrin PF00435.16 ETO23108.1 - 0.44 10.8 9.0 0.21 11.8 0.3 3.3 2 1 1 3 3 3 0 Spectrin repeat FlxA PF14282.1 ETO23108.1 - 0.5 10.3 10.1 0.36 10.7 0.6 3.2 3 0 0 3 3 3 0 FlxA-like protein AATF-Che1 PF13339.1 ETO23108.1 - 0.56 10.3 7.5 0.12 12.4 0.2 2.8 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor Allexi_40kDa PF05549.6 ETO23108.1 - 0.64 9.2 7.7 6.4 5.9 0.3 2.6 1 1 3 4 4 4 0 Allexivirus 40kDa protein Fmp27_WPPW PF10359.4 ETO23108.1 - 0.86 7.9 6.5 2.6 6.3 0.1 2.3 2 1 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF972 PF06156.8 ETO23108.1 - 0.99 9.7 9.5 5.3 7.4 0.9 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF972) YlqD PF11068.3 ETO23108.1 - 1.1 9.3 10.7 0.22 11.5 1.5 2.8 2 1 1 3 3 3 0 YlqD protein DUF904 PF06005.7 ETO23108.1 - 1.2 9.5 13.1 0.22 11.8 1.1 2.9 3 0 0 3 3 2 0 Protein of unknown function (DUF904) DUF4407 PF14362.1 ETO23108.1 - 3.9 6.3 8.8 1.3 7.9 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) TBPIP PF07106.8 ETO23108.1 - 7 6.1 11.2 3.2 7.2 0.9 2.8 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GreA_GreB_N PF03449.10 ETO23108.1 - 7.5 6.6 7.0 3.3 7.8 0.2 3.4 3 1 0 4 4 4 0 Transcription elongation factor, N-terminal TipAS PF07739.8 ETO23109.1 - 0.0054 17.0 2.9 0.024 14.9 0.3 2.2 2 0 0 2 2 2 1 TipAS antibiotic-recognition domain HSCB_C PF07743.8 ETO23109.1 - 0.07 13.5 6.1 20 5.7 0.0 3.3 2 1 0 3 3 3 0 HSCB C-terminal oligomerisation domain Xpo1 PF08389.7 ETO23109.1 - 0.074 12.9 1.4 0.24 11.2 1.0 1.8 1 1 0 1 1 1 0 Exportin 1-like protein nsp8 PF08717.5 ETO23109.1 - 0.12 11.9 2.6 0.54 9.8 0.3 2.1 2 0 0 2 2 2 0 nsp8 replicase ThylakoidFormat PF11264.3 ETO23109.1 - 0.46 10.0 4.7 0.25 10.9 1.2 2.0 1 1 0 2 2 2 0 Thylakoid formation protein SBP_bac_7 PF03480.8 ETO23109.1 - 0.96 8.4 6.3 5.9 5.9 0.3 2.4 1 1 1 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 DUF3782 PF12644.2 ETO23109.1 - 2 8.2 6.8 9.7 6.0 4.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) RPEL PF02755.10 ETO23112.1 - 9.7e-17 59.7 23.9 8.6e-08 31.2 0.5 4.7 4 0 0 4 4 4 4 RPEL repeat ARA70 PF12489.3 ETO23113.1 - 0.00086 19.2 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Nuclear coactivator RasGAP PF00616.14 ETO23113.1 - 0.0018 17.9 0.4 0.0028 17.3 0.3 1.5 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase Selenoprotein_S PF06936.6 ETO23114.1 - 0.00034 20.1 13.3 0.00043 19.8 9.2 1.1 1 0 0 1 1 1 1 Selenoprotein S (SelS) OAD_gamma PF04277.8 ETO23114.1 - 0.022 15.1 0.9 0.022 15.1 0.6 3.2 1 1 1 2 2 1 0 Oxaloacetate decarboxylase, gamma chain Ycf1 PF05758.7 ETO23114.1 - 0.033 11.9 16.1 0.048 11.3 11.1 1.3 1 0 0 1 1 1 0 Ycf1 Hid1 PF12722.2 ETO23114.1 - 0.18 9.4 13.6 0.21 9.2 9.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ETRAMP PF09716.5 ETO23114.1 - 0.7 9.8 7.0 11 6.0 4.8 2.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF4551 PF15087.1 ETO23114.1 - 1.8 6.8 17.1 2.2 6.5 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Shisa PF13908.1 ETO23114.1 - 2.1 8.5 6.3 25 4.9 4.4 2.1 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF572 PF04502.8 ETO23114.1 - 4.8 6.2 31.8 6.8 5.8 22.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) MIP-T3 PF10243.4 ETO23114.1 - 5.3 5.3 44.1 6.5 5.0 30.6 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1510 PF07423.6 ETO23114.1 - 6.6 6.0 37.5 0.14 11.5 13.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1510) Zip PF02535.17 ETO23114.1 - 7.5 5.4 10.5 17 4.3 7.3 1.6 1 1 0 1 1 1 0 ZIP Zinc transporter Calpain_III PF01067.17 ETO23115.1 - 0.059 13.0 0.2 0.07 12.7 0.2 1.2 1 0 0 1 1 1 0 Calpain large subunit, domain III ARF7EP_C PF14949.1 ETO23115.1 - 1.1 9.6 4.0 2.3 8.6 2.4 1.7 1 1 1 2 2 2 0 ARF7 effector protein C-terminus PH PF00169.24 ETO23116.1 - 0.00046 20.3 2.8 0.00051 20.1 0.8 2.0 2 0 0 2 2 2 1 PH domain PH_6 PF15406.1 ETO23116.1 - 0.0075 16.3 0.0 0.019 14.9 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Pkinase PF00069.20 ETO23116.1 - 0.012 14.7 0.1 0.025 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain PH_3 PF14593.1 ETO23116.1 - 0.029 14.2 1.3 0.11 12.4 0.9 2.1 1 1 0 1 1 1 0 PH domain PH_11 PF15413.1 ETO23116.1 - 0.075 13.2 4.3 0.15 12.3 1.0 2.7 3 0 0 3 3 3 0 Pleckstrin homology domain Mcp5_PH PF12814.2 ETO23116.1 - 0.086 12.7 1.8 0.22 11.4 1.3 1.8 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology Mucin PF01456.12 ETO23117.1 - 0.62 9.8 21.0 0.32 10.7 9.2 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Utp14 PF04615.8 ETO23117.1 - 0.71 7.9 26.5 0.88 7.6 18.4 1.1 1 0 0 1 1 1 0 Utp14 protein Nop14 PF04147.7 ETO23117.1 - 1.2 6.9 27.5 1.7 6.4 19.1 1.2 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 ETO23117.1 - 2 6.7 24.2 2.8 6.3 16.8 1.1 1 0 0 1 1 1 0 Daxx Family Mito_carr PF00153.22 ETO23118.1 - 1.7e-25 88.5 0.1 3.4e-19 68.3 0.0 2.7 2 1 0 2 2 2 2 Mitochondrial carrier protein EII-Sor PF03609.9 ETO23118.1 - 0.0061 15.8 0.7 0.08 12.2 0.0 2.1 2 0 0 2 2 2 1 PTS system sorbose-specific iic component PLRV_ORF5 PF01690.12 ETO23118.1 - 0.079 12.1 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Mito_carr PF00153.22 ETO23119.1 - 2.9e-30 103.8 1.6 1.7e-18 66.0 0.3 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF4257 PF14074.1 ETO23119.1 - 0.036 13.7 0.1 0.079 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4257) MBOAT_2 PF13813.1 ETO23120.1 - 0.0071 16.4 1.5 0.0071 16.4 1.1 1.9 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family DUF1129 PF06570.6 ETO23120.1 - 0.67 9.2 9.6 3.2 6.9 1.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) Abhydrolase_5 PF12695.2 ETO23121.1 - 1.2e-16 60.7 0.2 6.3e-09 35.7 0.0 2.8 3 0 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETO23121.1 - 1.2e-09 38.4 0.1 0.0017 18.2 0.0 2.6 3 0 0 3 3 3 2 Alpha/beta hydrolase family Caldesmon PF02029.10 ETO23121.1 - 7.9e-08 31.1 9.2 7.9e-08 31.1 6.4 1.5 2 0 0 2 2 2 1 Caldesmon Peptidase_S9 PF00326.16 ETO23121.1 - 2.6e-05 23.5 0.5 9e-05 21.7 0.1 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 ETO23121.1 - 0.00092 18.7 3.0 0.041 13.3 0.1 2.9 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 ETO23121.1 - 0.0034 16.9 0.0 0.14 11.6 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.13 ETO23121.1 - 0.0039 16.5 0.3 0.012 14.8 0.1 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family Macoilin PF09726.4 ETO23121.1 - 0.22 9.7 26.9 0.39 8.9 18.7 1.3 1 0 0 1 1 1 0 Transmembrane protein WD40 PF00400.27 ETO23122.1 - 7.9e-57 187.2 12.1 6.8e-10 38.4 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO23122.1 - 1.6e-08 33.1 5.5 0.04 12.0 0.1 5.6 1 1 5 6 6 6 4 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO23122.1 - 5.6e-05 23.4 6.7 5.6e-05 23.4 4.7 2.3 3 0 0 3 3 3 1 TRAF-type zinc finger GerA PF03323.8 ETO23122.1 - 7.2 4.6 6.8 11 4.0 4.7 1.2 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein FA_desaturase PF00487.19 ETO23123.1 - 3.8e-26 92.0 21.1 6.1e-26 91.4 14.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase RhoGEF PF00621.15 ETO23124.1 - 6.4e-16 58.7 6.1 2.7e-14 53.4 1.1 2.7 2 1 1 3 3 3 2 RhoGEF domain PH PF00169.24 ETO23124.1 - 5.4e-12 45.8 0.3 5.4e-12 45.8 0.2 2.1 2 1 0 2 2 2 1 PH domain Hamartin PF04388.7 ETO23125.1 - 2.8 6.5 12.5 6.5 5.2 8.7 1.6 1 0 0 1 1 1 0 Hamartin protein DUF1675 PF07897.6 ETO23125.1 - 3.3 7.5 22.9 4.5 7.0 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) Amidase02_C PF12123.3 ETO23126.1 - 0.012 15.2 0.1 0.034 13.7 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase Thioredoxin_9 PF14595.1 ETO23129.1 - 0.34 10.4 2.0 0.23 11.0 0.4 1.6 2 0 0 2 2 2 0 Thioredoxin Fringe PF02434.11 ETO23130.1 - 0.00011 21.4 0.0 0.00032 20.0 0.0 1.9 1 1 0 1 1 1 1 Fringe-like BRCT PF00533.21 ETO23131.1 - 6.3e-06 26.2 0.2 0.00059 19.9 0.0 2.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Mem_trans PF03547.13 ETO23131.1 - 0.073 11.3 0.2 0.062 11.5 0.2 1.2 1 0 0 1 1 1 0 Membrane transport protein Nop14 PF04147.7 ETO23131.1 - 0.25 9.2 18.2 0.33 8.8 12.6 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 ETO23131.1 - 0.38 8.7 14.2 0.5 8.3 9.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Pox_RNA_Pol_19 PF05320.7 ETO23131.1 - 1.8 8.2 10.5 4.1 7.1 7.2 1.6 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Merozoite_SPAM PF07133.6 ETO23131.1 - 2.9 7.7 24.2 6.8 6.5 16.8 1.7 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CRT-like PF08627.5 ETO23132.1 - 0.017 15.0 1.8 0.018 14.9 0.3 1.7 2 0 0 2 2 2 0 CRT-like Sporozoite_P67 PF05642.6 ETO23132.1 - 0.025 12.4 3.1 0.028 12.3 2.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4211 PF13926.1 ETO23132.1 - 0.026 13.9 0.8 0.044 13.2 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4211) RXT2_N PF08595.6 ETO23132.1 - 0.046 13.5 2.8 0.063 13.0 2.0 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.4 ETO23132.1 - 0.084 11.5 3.0 0.1 11.2 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 ETO23132.1 - 0.13 11.8 2.7 0.18 11.2 1.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin LRS4 PF10422.4 ETO23132.1 - 0.62 9.3 6.6 1.1 8.6 4.6 1.4 1 1 0 1 1 1 0 Monopolin complex subunit LRS4 AIG1 PF04548.11 ETO23133.1 - 7.9e-09 34.9 0.0 1.2e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 AIG1 family TelA PF05816.6 ETO23133.1 - 0.084 11.5 0.2 0.16 10.6 0.0 1.5 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) SPO22 PF08631.5 ETO23134.1 - 0.0036 16.4 1.0 0.0041 16.2 0.7 1.2 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like ApoLp-III PF07464.6 ETO23134.1 - 0.011 15.7 7.5 0.017 15.1 5.2 1.4 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF4254 PF14063.1 ETO23134.1 - 0.02 14.5 0.3 0.02 14.5 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4254) DUF1043 PF06295.7 ETO23134.1 - 0.023 14.3 3.1 0.032 13.8 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) APG6 PF04111.7 ETO23134.1 - 0.028 13.4 8.6 0.034 13.2 6.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 CLAG PF03805.8 ETO23134.1 - 0.035 11.4 10.2 0.04 11.2 7.1 1.0 1 0 0 1 1 1 0 Cytoadherence-linked asexual protein V_ATPase_I PF01496.14 ETO23134.1 - 0.062 11.1 8.5 0.071 10.9 5.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Apolipoprotein PF01442.13 ETO23134.1 - 0.072 12.5 5.2 0.095 12.2 3.4 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Phage_GPA PF05840.8 ETO23134.1 - 0.075 11.7 3.8 0.086 11.5 2.6 1.1 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) Borrelia_P83 PF05262.6 ETO23134.1 - 0.14 10.4 8.5 0.16 10.1 5.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF1615 PF07759.7 ETO23134.1 - 0.16 10.6 2.7 0.2 10.4 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1615) Mob_Pre PF01076.14 ETO23134.1 - 0.17 11.5 10.6 0.19 11.3 7.3 1.2 1 0 0 1 1 1 0 Plasmid recombination enzyme AAA_11 PF13086.1 ETO23134.1 - 0.18 11.3 6.4 0.21 11.1 4.5 1.1 1 0 0 1 1 1 0 AAA domain DUF2785 PF10978.3 ETO23134.1 - 0.25 10.7 3.5 0.36 10.2 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2785) MMR_HSR1 PF01926.18 ETO23134.1 - 0.46 10.4 2.7 1.3 8.9 1.9 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Fib_alpha PF08702.5 ETO23134.1 - 0.67 10.0 9.7 0.42 10.7 5.6 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family OmpH PF03938.9 ETO23134.1 - 0.84 9.5 9.4 0.93 9.4 5.8 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) 60KD_IMP PF02096.15 ETO23134.1 - 0.97 9.0 5.3 1.3 8.6 3.6 1.2 1 0 0 1 1 1 0 60Kd inner membrane protein Ax_dynein_light PF10211.4 ETO23134.1 - 1.1 9.1 13.3 1.5 8.6 9.2 1.4 1 1 0 1 1 1 0 Axonemal dynein light chain DUF4200 PF13863.1 ETO23134.1 - 1.6 8.7 18.2 1.9 8.4 11.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) IncA PF04156.9 ETO23134.1 - 1.6 8.3 7.1 1.9 8.0 4.9 1.2 1 0 0 1 1 1 0 IncA protein TMPIT PF07851.8 ETO23134.1 - 2.1 7.3 11.1 2.7 6.9 7.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein Syntaxin PF00804.20 ETO23134.1 - 2.3 8.4 13.8 18 5.5 9.6 2.3 1 1 0 1 1 1 0 Syntaxin PurS PF02700.9 ETO23134.1 - 2.8 7.9 9.1 2.8 7.9 0.3 2.3 2 0 0 2 2 2 0 Phosphoribosylformylglycinamidine (FGAM) synthase DUF1664 PF07889.7 ETO23134.1 - 3.9 7.2 8.3 6.2 6.6 5.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Enkurin PF13864.1 ETO23134.1 - 4.7 7.4 12.6 6 7.1 3.4 2.3 1 1 1 2 2 2 0 Calmodulin-binding Pyr_redox_2 PF07992.9 ETO23137.1 - 8.7e-07 29.0 0.0 1.5e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETO23137.1 - 0.054 13.2 0.0 0.48 10.1 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pab87_oct PF13969.1 ETO23137.1 - 0.089 12.8 0.0 0.4 10.8 0.0 2.1 2 0 0 2 2 2 0 Pab87 octamerisation domain TMA7 PF09072.5 ETO23138.1 - 0.031 14.7 1.2 0.064 13.7 0.9 1.5 1 0 0 1 1 1 0 Translation machinery associated TMA7 Pox_Ag35 PF03286.9 ETO23138.1 - 0.15 11.5 11.6 0.24 10.8 8.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Zip PF02535.17 ETO23138.1 - 4.4 6.2 6.1 4.7 6.1 4.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Acetyltransf_1 PF00583.19 ETO23139.1 - 1.2e-10 41.2 0.0 2.6e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETO23139.1 - 2.9e-09 36.9 0.1 5.9e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETO23139.1 - 8.2e-07 28.7 0.0 2.1e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 ETO23139.1 - 2.6e-06 27.5 0.0 3.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 ETO23139.1 - 0.00035 20.7 0.0 0.00063 19.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETO23139.1 - 0.003 17.4 0.0 0.013 15.3 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Cation_efflux PF01545.16 ETO23140.1 - 9.7e-40 136.4 12.0 1.1e-39 136.2 8.3 1.0 1 0 0 1 1 1 1 Cation efflux family zf-RanBP PF00641.13 ETO23141.1 - 0.0018 17.3 1.3 0.0018 17.3 0.9 2.6 2 1 0 2 2 2 1 Zn-finger in Ran binding protein and others PhnA_Zn_Ribbon PF08274.7 ETO23141.1 - 0.13 12.0 0.8 0.13 12.0 0.5 2.9 3 0 0 3 3 3 0 PhnA Zinc-Ribbon CAP_GLY PF01302.20 ETO23142.1 - 6.2e-16 57.8 2.1 6.8e-15 54.5 0.2 2.3 2 0 0 2 2 2 2 CAP-Gly domain B56 PF01603.15 ETO23143.1 - 4.7e-57 193.4 11.3 3.2e-52 177.5 3.9 2.3 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) DUF3439 PF11921.3 ETO23143.1 - 6.4 6.5 11.6 0.22 11.2 2.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) Voltage_CLC PF00654.15 ETO23144.1 - 7.5e-53 179.7 14.5 7.5e-53 179.7 10.1 2.2 1 1 1 2 2 2 2 Voltage gated chloride channel DUF4231 PF14015.1 ETO23144.1 - 0.98 9.4 9.1 2.8 7.9 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Laminin_G_3 PF13385.1 ETO23145.1 - 3.6e-06 27.2 0.0 8.5e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily zf-C2H2 PF00096.21 ETO23146.1 - 0.076 13.3 0.1 0.24 11.8 0.1 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type EF-hand_7 PF13499.1 ETO23147.1 - 5.1e-17 61.7 4.1 7.2e-09 35.6 0.3 2.4 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 ETO23147.1 - 2e-16 59.3 5.7 7.6e-09 35.0 0.4 2.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 ETO23147.1 - 9e-16 55.9 7.2 5e-08 31.6 0.2 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 ETO23147.1 - 5.5e-11 41.3 6.4 4.5e-06 26.0 0.1 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 ETO23147.1 - 2.9e-09 35.8 5.9 1.3e-05 24.2 0.2 3.0 3 0 0 3 3 3 2 EF hand TerB PF05099.8 ETO23147.1 - 0.00062 19.5 0.2 0.0042 16.8 0.0 2.2 1 1 2 3 3 3 1 Tellurite resistance protein TerB UPF0154 PF03672.8 ETO23147.1 - 0.0015 18.1 0.0 0.23 11.0 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) EF-hand_4 PF12763.2 ETO23147.1 - 0.016 14.9 2.3 0.61 9.8 0.1 2.5 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF1722 PF08349.6 ETO23147.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) PUB PF09409.5 ETO23148.1 - 1.8e-31 107.7 1.2 3.3e-12 45.9 0.0 3.3 3 0 0 3 3 3 3 PUB domain Sina PF03145.11 ETO23149.1 - 6.6e-07 29.1 2.4 1.9e-06 27.7 1.6 1.8 1 0 0 1 1 1 1 Seven in absentia protein family zf-C3HC4_2 PF13923.1 ETO23149.1 - 0.0026 17.7 11.9 0.0094 15.9 8.2 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO23149.1 - 0.0039 16.8 11.0 0.012 15.3 7.6 1.9 1 0 0 1 1 1 1 zinc-RING finger domain MutS_III PF05192.13 ETO23151.1 - 0.0085 15.8 0.6 0.0085 15.8 0.4 1.8 2 0 0 2 2 2 1 MutS domain III HTH_1 PF00126.22 ETO23152.1 - 0.012 15.3 0.2 0.031 13.9 0.1 1.7 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Serinc PF03348.10 ETO23152.1 - 4.3 5.9 10.1 0.56 8.8 0.5 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) Mannosyl_trans3 PF11051.3 ETO23153.1 - 1.2e-06 28.1 0.0 1.3e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative DUF1450 PF07293.6 ETO23154.1 - 0.056 13.4 1.3 11 6.0 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1450) Glyoxalase PF00903.20 ETO23155.1 - 9.6e-17 61.1 0.1 1.5e-16 60.5 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 ETO23155.1 - 6.6e-05 22.8 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 ETO23155.1 - 0.0075 16.8 0.0 0.015 15.8 0.0 1.6 1 0 0 1 1 1 1 Glyoxalase-like domain MutS_IV PF05190.13 ETO23155.1 - 0.037 14.2 0.1 0.08 13.1 0.1 1.5 1 0 0 1 1 1 0 MutS family domain IV SRI PF08236.6 ETO23156.1 - 0.031 14.2 2.3 0.031 14.2 1.6 2.0 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain ETRAMP PF09716.5 ETO23156.1 - 9 6.3 10.9 30 4.6 7.6 2.0 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) CN_hydrolase PF00795.17 ETO23157.1 - 2e-27 95.7 0.0 2.7e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TauD PF02668.11 ETO23157.1 - 0.0035 17.0 0.0 0.0055 16.4 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Mob1_phocein PF03637.12 ETO23159.1 - 5.2e-32 110.9 8.5 1.7e-19 70.1 0.0 2.1 2 0 0 2 2 2 2 Mob1/phocein family Macoilin PF09726.4 ETO23160.1 - 0.17 10.1 12.8 0.2 9.9 8.9 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF2052 PF09747.4 ETO23160.1 - 2.7 7.8 9.4 5 7.0 6.5 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF4281 PF14108.1 ETO23162.1 - 0.075 13.1 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4281) U-box PF04564.10 ETO23163.1 - 2.9e-21 75.2 0.1 5.8e-21 74.2 0.1 1.5 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.3 ETO23163.1 - 0.0001 21.7 0.0 0.00027 20.4 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Zip PF02535.17 ETO23163.1 - 0.00071 18.6 4.5 0.0013 17.8 3.1 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter zf-RING_UBOX PF13445.1 ETO23163.1 - 0.0032 17.1 0.2 0.012 15.2 0.0 2.1 2 0 0 2 2 2 1 RING-type zinc-finger Gly-zipper_OmpA PF13436.1 ETO23163.1 - 0.013 15.1 6.8 0.013 15.1 4.7 1.8 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Pex14_N PF04695.8 ETO23163.1 - 0.031 14.3 1.5 0.082 12.9 0.2 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sporozoite_P67 PF05642.6 ETO23163.1 - 0.031 12.1 0.1 0.039 11.8 0.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Gly-zipper_Omp PF13488.1 ETO23163.1 - 0.04 13.5 19.9 0.5 10.0 13.8 2.1 1 1 0 1 1 1 0 Glycine zipper Secretin_N_2 PF07655.8 ETO23163.1 - 0.046 14.1 8.4 0.1 13.0 5.8 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain MRP-L46 PF11788.3 ETO23163.1 - 0.14 12.7 6.3 3 8.5 1.1 2.5 2 0 0 2 2 2 0 39S mitochondrial ribosomal protein L46 Gly-zipper_YMGG PF13441.1 ETO23163.1 - 2.8 7.5 19.7 11 5.6 13.7 1.8 1 1 0 1 1 1 0 YMGG-like Gly-zipper Tom22 PF04281.8 ETO23163.1 - 3.2 7.2 8.6 3.7 7.0 4.5 2.1 1 1 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 DUF2457 PF10446.4 ETO23163.1 - 3.5 6.2 16.0 6 5.4 11.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) WD40 PF00400.27 ETO23164.1 - 2.6e-40 134.9 11.6 1.8e-11 43.4 0.2 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO23164.1 - 0.00044 19.1 0.9 0.21 10.2 0.0 2.9 1 1 1 2 2 2 2 Nup133 N terminal like PD40 PF07676.7 ETO23164.1 - 0.18 11.4 3.7 8.1 6.2 0.1 3.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Cyanate_lyase PF02560.9 ETO23165.1 - 9.4e-26 89.1 0.0 1.5e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_3 PF01381.17 ETO23165.1 - 0.0053 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 ETO23165.1 - 0.024 14.6 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.1 ETO23165.1 - 0.063 12.6 0.2 4.1 6.8 0.0 3.2 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding DUF2316 PF10078.4 ETO23165.1 - 0.071 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) HTH_Mga PF08280.6 ETO23165.1 - 0.079 12.7 0.3 0.3 10.8 0.0 2.0 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain FYVE PF01363.16 ETO23166.1 - 1.7e-09 37.4 12.1 1.7e-09 37.4 8.4 2.6 3 0 0 3 3 3 1 FYVE zinc finger RCC1 PF00415.13 ETO23168.1 - 5.4e-09 36.1 3.1 0.069 13.3 0.0 6.1 5 2 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO23168.1 - 9.2e-06 25.1 10.8 0.0096 15.5 0.0 5.1 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat DUF732 PF05305.9 ETO23168.1 - 0.11 12.6 0.0 2.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF732) Apo-CII PF05355.6 ETO23169.1 - 0.074 12.9 1.0 14 5.5 0.0 2.3 2 0 0 2 2 2 0 Apolipoprotein C-II DUF563 PF04577.9 ETO23171.1 - 6e-21 75.3 0.0 7.2e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) L_protein_N PF15518.1 ETO23171.1 - 0.017 14.5 0.2 0.023 14.0 0.1 1.2 1 0 0 1 1 1 0 L protein N-terminus RED_N PF07808.8 ETO23172.1 - 6.3e-16 58.3 13.1 6.3e-16 58.3 9.1 5.6 3 1 0 3 3 3 1 RED-like protein N-terminal region MSC PF09402.5 ETO23173.1 - 0.0019 16.9 8.2 0.0052 15.5 5.7 1.7 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain Prothymosin PF03247.9 ETO23173.1 - 0.003 17.6 17.5 0.003 17.6 12.1 2.8 2 1 0 2 2 2 1 Prothymosin/parathymosin family S1FA PF04689.8 ETO23173.1 - 1.6 8.6 7.4 0.21 11.4 1.6 2.2 2 0 0 2 2 2 0 DNA binding protein S1FA Med3 PF11593.3 ETO23174.1 - 0.52 9.4 10.6 1.7 7.7 7.5 1.6 1 1 1 2 2 2 0 Mediator complex subunit 3 fungal WD40 PF00400.27 ETO23176.1 - 1.1e-05 25.0 4.2 1.2 9.1 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat RICTOR_N PF14664.1 ETO23178.1 - 8.6e-07 27.8 0.0 0.01 14.4 0.0 2.1 2 0 0 2 2 2 2 Rapamycin-insensitive companion of mTOR, N-term TAP42 PF04177.7 ETO23179.1 - 4.2e-15 55.5 0.4 4.4e-15 55.4 0.3 1.0 1 0 0 1 1 1 1 TAP42-like family RNA_pol_Rpb2_3 PF04565.11 ETO23180.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 3 TAP42 PF04177.7 ETO23180.1 - 0.79 8.6 19.8 0.02 13.8 0.3 2.4 2 1 0 2 2 2 0 TAP42-like family RRM_1 PF00076.17 ETO23181.1 - 9.4e-18 63.6 0.0 1.7e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO23181.1 - 2.7e-11 43.2 0.0 5e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO23181.1 - 1.7e-08 34.1 0.0 3.8e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) STT3 PF02516.9 ETO23182.1 - 0.066 12.1 0.5 0.12 11.2 0.3 1.5 1 1 0 1 1 1 0 Oligosaccharyl transferase STT3 subunit LAG1-DNAbind PF09271.6 ETO23182.1 - 0.29 11.6 7.9 0.38 11.2 4.7 1.8 1 1 0 1 1 1 0 LAG1, DNA binding Mem_trans PF03547.13 ETO23182.1 - 1.8 6.7 7.5 0.27 9.4 0.1 2.2 1 1 1 2 2 2 0 Membrane transport protein Tom37_C PF11801.3 ETO23183.1 - 0.68 9.7 2.7 1 9.1 1.8 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain DUF1777 PF08648.7 ETO23183.1 - 2.3 7.9 27.1 2.7 7.7 18.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) PRP38_assoc PF12871.2 ETO23183.1 - 2.3 8.7 23.1 5.3 7.6 16.0 1.6 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DNA_repr_REX1B PF14966.1 ETO23184.1 - 1.9e-09 37.7 2.8 2.3e-09 37.5 1.9 1.1 1 0 0 1 1 1 1 DNA repair REX1-B Allantoicase PF03561.10 ETO23184.1 - 0.033 13.6 0.2 0.041 13.3 0.1 1.1 1 0 0 1 1 1 0 Allantoicase repeat Ppx-GppA PF02541.11 ETO23184.1 - 0.087 11.9 1.0 0.096 11.8 0.7 1.1 1 0 0 1 1 1 0 Ppx/GppA phosphatase family RNB PF00773.14 ETO23185.1 - 5.8e-38 130.9 0.1 5.8e-38 130.9 0.1 2.9 3 0 0 3 3 3 1 RNB domain RNase_H2-Ydr279 PF09468.5 ETO23186.1 - 0.07 12.3 12.5 0.13 11.3 8.7 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) HSP90 PF00183.13 ETO23186.1 - 0.31 9.3 23.8 0.58 8.4 16.5 1.3 1 0 0 1 1 1 0 Hsp90 protein DUF1510 PF07423.6 ETO23186.1 - 0.36 10.1 20.5 0.83 8.9 14.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 ETO23186.1 - 0.58 8.1 12.7 0.84 7.5 8.8 1.2 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.1 ETO23186.1 - 0.77 9.4 7.6 2 8.0 5.3 1.8 1 0 0 1 1 1 0 FAM176 family SdpI PF13630.1 ETO23186.1 - 0.83 9.4 3.8 2.5 7.8 2.6 1.8 1 0 0 1 1 1 0 SdpI/YhfL protein family SprA-related PF12118.3 ETO23186.1 - 0.95 8.7 17.0 1.7 7.9 11.8 1.3 1 0 0 1 1 1 0 SprA-related family CENP-B_dimeris PF09026.5 ETO23186.1 - 1.3 9.2 9.7 4 7.7 6.7 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sec62 PF03839.11 ETO23186.1 - 3.2 7.0 17.0 8.1 5.7 11.8 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 DDHD PF02862.12 ETO23186.1 - 5.3 6.7 13.8 12 5.6 9.5 1.6 1 0 0 1 1 1 0 DDHD domain NikR_C PF08753.6 ETO23187.1 - 0.012 15.5 0.2 0.028 14.3 0.2 1.6 1 0 0 1 1 1 0 NikR C terminal nickel binding domain Minor_capsid_2 PF11114.3 ETO23188.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Minor capsid protein PAP_assoc PF03828.14 ETO23190.1 - 5.7e-14 51.7 0.4 1.1e-13 50.8 0.3 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase DUF3643 PF12356.3 ETO23191.1 - 0.061 12.6 0.1 0.061 12.6 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3643) Neocarzinostat PF00960.13 ETO23191.1 - 0.1 12.5 0.5 0.17 11.7 0.4 1.3 1 0 0 1 1 1 0 Neocarzinostatin family Ycf1 PF05758.7 ETO23191.1 - 0.21 9.2 3.6 0.23 9.1 2.5 1.1 1 0 0 1 1 1 0 Ycf1 HCV_NS5a_C PF12941.2 ETO23191.1 - 0.46 10.0 11.8 0.021 14.3 3.4 1.9 1 1 1 2 2 2 0 HCV NS5a protein C-terminal region CLASP_N PF12348.3 ETO23193.1 - 0.016 14.6 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 CLASP N terminal Glyco_transf_18 PF15024.1 ETO23194.1 - 9.8e-13 47.2 0.2 5.6e-12 44.7 0.2 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 18 Ninjurin PF04923.7 ETO23195.1 - 0.15 11.7 0.2 0.15 11.7 0.1 2.0 2 1 0 2 2 2 0 Ninjurin TIP_N PF12457.3 ETO23195.1 - 0.25 11.4 7.6 0.45 10.5 5.3 1.4 1 0 0 1 1 1 0 Tuftelin interacting protein N terminal DUF3504 PF12012.3 ETO23195.1 - 0.3 10.8 7.5 0.18 11.5 4.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3504) DUF1492 PF07374.6 ETO23195.1 - 0.38 10.8 4.5 0.093 12.8 1.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1492) Protocadherin PF08374.6 ETO23195.1 - 1.8 8.1 10.0 2.2 7.8 6.9 1.2 1 0 0 1 1 1 0 Protocadherin LAGLIDADG_1 PF00961.14 ETO23195.1 - 4.5 7.8 10.8 6.1 7.4 7.5 1.1 1 0 0 1 1 1 0 LAGLIDADG endonuclease Kelch_1 PF01344.20 ETO23196.1 - 0.0002 20.8 0.4 0.0002 20.8 0.3 3.1 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 ETO23196.1 - 0.00036 20.1 1.0 0.047 13.4 0.0 3.8 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO23196.1 - 0.00084 19.0 4.3 0.0027 17.4 0.0 2.9 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO23196.1 - 0.0011 19.0 3.1 0.29 11.3 0.1 3.6 2 1 1 3 3 3 2 Kelch motif Kelch_3 PF13415.1 ETO23196.1 - 0.014 15.5 0.0 0.041 14.0 0.0 1.9 1 0 0 1 1 1 0 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO23196.1 - 2.9 7.9 6.4 0.3 11.0 0.2 2.6 4 0 0 4 4 4 0 Kelch motif Ndc1_Nup PF09531.5 ETO23197.1 - 8.2 4.7 7.2 9.7 4.4 5.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Annexin PF00191.15 ETO23198.1 - 1.1e-07 31.6 0.0 2.8e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 Annexin EF-hand_1 PF00036.27 ETO23198.1 - 2.9e-05 23.0 0.0 0.00015 20.8 0.0 2.3 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 ETO23198.1 - 0.0006 19.4 0.0 0.0038 16.9 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 ETO23198.1 - 0.012 14.9 0.1 0.05 12.9 0.0 2.2 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.1 ETO23198.1 - 0.044 13.9 0.0 0.11 12.5 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair Annexin PF00191.15 ETO23199.1 - 2.3e-25 88.2 13.4 7.4e-13 48.1 0.0 5.9 6 1 0 6 6 6 4 Annexin Creatinase_N PF01321.13 ETO23199.1 - 0.021 15.3 0.1 0.079 13.4 0.0 1.9 2 0 0 2 2 2 0 Creatinase/Prolidase N-terminal domain DUF1777 PF08648.7 ETO23201.1 - 0.00024 20.8 66.0 0.00024 20.8 45.8 3.7 1 1 2 3 3 3 2 Protein of unknown function (DUF1777) Glyco_hydro_32C PF08244.7 ETO23202.1 - 1.1e-10 41.7 0.0 2.4e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal UCH PF00443.24 ETO23203.1 - 1.1e-13 50.9 6.8 1.6e-12 47.1 4.7 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO23203.1 - 1.5e-06 27.9 0.9 1.5e-06 27.9 0.6 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF445 PF04286.7 ETO23203.1 - 0.04 13.4 0.7 0.048 13.1 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Band_3_cyto PF07565.8 ETO23203.1 - 0.36 10.3 3.8 0.77 9.2 0.1 2.0 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Eapp_C PF10238.4 ETO23203.1 - 0.59 10.0 12.0 0.28 11.0 0.4 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF912 PF06024.7 ETO23204.1 - 0.019 14.9 1.2 0.019 14.9 0.9 2.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DM PF00751.13 ETO23204.1 - 0.045 13.2 1.2 0.089 12.3 0.8 1.4 1 0 0 1 1 1 0 DM DNA binding domain Vma12 PF11712.3 ETO23204.1 - 0.051 13.2 1.8 0.058 13.1 0.2 1.8 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF1129 PF06570.6 ETO23204.1 - 0.27 10.5 4.7 0.76 9.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF4131 PF13567.1 ETO23204.1 - 6.7 6.0 6.1 73 2.7 4.2 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Intein_splicing PF14890.1 ETO23205.1 - 0.054 12.3 0.1 0.072 11.9 0.1 1.1 1 0 0 1 1 1 0 Intein splicing domain Coiled PF05710.7 ETO23205.1 - 5.2 7.5 11.1 1.2 9.6 0.7 2.7 2 0 0 2 2 2 0 Coiled coil Lzipper-MIP1 PF14389.1 ETO23207.1 - 0.11 12.5 4.1 1.3 9.1 2.0 2.4 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Innate_immun PF12782.2 ETO23207.1 - 2.2 7.4 16.3 0.056 12.6 7.0 1.7 2 0 0 2 2 2 0 Invertebrate innate immunity transcript family MtN3_slv PF03083.11 ETO23208.1 - 8.9e-19 67.1 0.2 8.8e-17 60.7 0.0 2.3 2 1 0 2 2 2 2 Sugar efflux transporter for intercellular exchange TAT_signal PF10518.4 ETO23208.1 - 0.0059 16.5 1.2 0.041 13.9 1.1 2.2 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence A_deaminase PF00962.17 ETO23209.1 - 3.6e-15 55.7 0.1 3.5e-07 29.4 0.0 2.2 2 0 0 2 2 2 2 Adenosine/AMP deaminase ING PF12998.2 ETO23210.1 - 0.0022 18.2 5.7 0.0022 18.2 3.9 2.9 1 1 2 3 3 3 1 Inhibitor of growth proteins N-terminal histone-binding LuxC PF05893.9 ETO23210.1 - 0.0024 16.6 0.2 0.0049 15.6 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) zf-C3HC4_3 PF13920.1 ETO23212.1 - 4.9e-10 38.9 4.6 7.9e-10 38.2 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO23212.1 - 0.0034 17.3 8.6 0.0061 16.5 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO23212.1 - 0.035 13.8 6.7 0.068 12.9 4.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain ProRS-C_1 PF09180.6 ETO23212.1 - 0.072 13.0 0.4 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 Prolyl-tRNA synthetase, C-terminal V_ATPase_I PF01496.14 ETO23212.1 - 3 5.5 9.6 5 4.8 6.7 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Competence PF03772.11 ETO23213.1 - 0.85 8.6 21.8 0.59 9.1 9.8 2.7 2 2 0 2 2 2 0 Competence protein 7tm_3 PF00003.17 ETO23214.1 - 8e-24 84.2 22.9 8e-24 84.2 15.9 1.5 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR Chlam_PMP PF02415.12 ETO23214.1 - 0.00015 21.7 57.8 0.93 9.8 0.1 11.4 12 0 0 12 12 12 6 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF2678 PF10856.3 ETO23214.1 - 1.6 8.4 8.9 4.6 7.0 1.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2678) Kelch_3 PF13415.1 ETO23215.1 - 1.9e-05 24.7 1.0 0.19 11.9 0.0 4.6 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO23215.1 - 0.00046 19.8 4.3 2.2 8.1 0.0 5.4 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO23215.1 - 0.0038 17.3 4.6 6 7.2 0.0 4.9 5 0 0 5 5 5 1 Kelch motif Kelch_5 PF13854.1 ETO23215.1 - 0.016 15.1 5.7 7.3 6.6 0.1 4.3 4 0 0 4 4 4 0 Kelch motif Kelch_1 PF01344.20 ETO23215.1 - 0.26 10.8 10.0 3 7.4 0.0 5.2 5 0 0 5 5 5 0 Kelch motif SIP1 PF04938.7 ETO23216.1 - 9e-27 93.9 0.9 1.2e-26 93.5 0.6 1.1 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) cNMP_binding PF00027.24 ETO23219.1 - 2.6e-17 62.4 0.0 2.2e-10 40.2 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DUF608 PF04685.8 ETO23219.1 - 0.0062 15.2 0.0 0.011 14.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF608 FDF PF09532.5 ETO23220.1 - 0.16 12.4 2.4 0.32 11.5 1.7 1.6 1 1 0 1 1 1 0 FDF domain ADP_ribosyl_GH PF03747.9 ETO23221.1 - 6.9e-30 104.8 0.1 9.9e-30 104.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Podoplanin PF05808.6 ETO23223.1 - 0.00027 20.5 4.5 0.0014 18.2 0.1 2.3 2 0 0 2 2 2 1 Podoplanin Kelch_3 PF13415.1 ETO23223.1 - 0.005 16.9 0.0 5.2 7.3 0.0 3.4 3 0 0 3 3 3 1 Galactose oxidase, central domain DUF2668 PF10873.3 ETO23223.1 - 0.0073 16.4 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2668) Rax2 PF12768.2 ETO23223.1 - 0.017 14.3 0.9 0.33 10.1 0.4 2.3 1 1 0 1 1 1 0 Cortical protein marker for cell polarity Syndecan PF01034.15 ETO23223.1 - 0.06 13.0 0.1 0.06 13.0 0.1 1.8 2 0 0 2 2 2 0 Syndecan domain MLANA PF14991.1 ETO23223.1 - 0.079 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A DUF4328 PF14219.1 ETO23223.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) Kelch_5 PF13854.1 ETO23223.1 - 0.14 12.1 0.4 3.3 7.7 0.1 2.9 3 0 0 3 3 3 0 Kelch motif MtrF PF09472.5 ETO23223.1 - 0.14 11.4 2.0 0.27 10.4 1.4 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) SAM_1 PF00536.25 ETO23225.1 - 0.00067 19.7 0.1 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RhoGAP PF00620.22 ETO23227.1 - 0.00012 21.7 0.0 0.00023 20.8 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain DUF2841 PF11001.3 ETO23227.1 - 0.055 13.3 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2841) DUF452 PF04301.8 ETO23228.1 - 0.0012 18.2 0.0 0.0016 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF452) DUF4272 PF14094.1 ETO23228.1 - 0.16 10.9 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4272) zf-RanBP PF00641.13 ETO23229.1 - 0.00034 19.6 0.6 0.0011 17.9 0.4 1.9 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Josephin PF02099.12 ETO23229.1 - 0.069 12.7 0.9 0.23 11.0 0.1 2.1 2 0 0 2 2 2 0 Josephin Ras PF00071.17 ETO23230.1 - 5.9e-18 64.7 0.1 2.2e-10 40.1 0.0 2.4 1 1 1 2 2 2 2 Ras family Miro PF08477.8 ETO23230.1 - 0.012 16.1 0.1 0.21 12.1 0.0 2.5 2 1 1 3 3 3 0 Miro-like protein SRP-alpha_N PF04086.8 ETO23232.1 - 0.05 12.9 2.4 0.058 12.7 1.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Atrophin-1 PF03154.10 ETO23232.1 - 0.12 10.5 5.2 0.14 10.2 3.6 1.0 1 0 0 1 1 1 0 Atrophin-1 family Apis_Csd PF11671.3 ETO23232.1 - 0.22 11.2 1.9 0.34 10.7 1.3 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein DDRGK PF09756.4 ETO23232.1 - 0.32 10.3 8.1 0.4 10.0 5.6 1.1 1 0 0 1 1 1 0 DDRGK domain MIP-T3 PF10243.4 ETO23233.1 - 0.0067 14.9 40.9 0.0097 14.4 28.4 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF936 PF06075.7 ETO23233.1 - 0.19 10.5 22.4 0.019 13.9 12.5 1.4 2 0 0 2 2 2 0 Plant protein of unknown function (DUF936) Plasmodium_Vir PF05795.6 ETO23234.1 - 0.0018 17.5 17.3 0.024 13.8 7.4 2.1 1 1 1 2 2 2 2 Plasmodium vivax Vir protein Hid1 PF12722.2 ETO23234.1 - 0.96 7.0 19.4 1.1 6.7 13.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ebola_NP PF05505.7 ETO23234.1 - 1.1 7.2 11.2 1.3 7.0 7.8 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein GAGA_bind PF06217.7 ETO23234.1 - 1.1 9.1 15.3 1.4 8.8 10.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family UPF0560 PF10577.4 ETO23234.1 - 1.1 7.3 12.0 1.3 7.1 8.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Hex_IIIa PF02455.11 ETO23234.1 - 4 6.0 12.0 4.6 5.7 8.3 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) DUF1675 PF07897.6 ETO23234.1 - 7 6.4 15.2 8.3 6.1 10.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF3728 PF12528.3 ETO23234.1 - 8.8 6.7 6.6 1.9 8.9 0.9 2.4 1 1 1 2 2 2 0 Prepilin peptidase dependent protein C (DUF3728) ATG11 PF10377.4 ETO23235.1 - 0.056 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Autophagy-related protein 11 NST1 PF13945.1 ETO23237.1 - 0.34 10.9 3.6 0.62 10.0 2.5 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator DEAD PF00270.24 ETO23240.1 - 1.4e-39 135.3 0.3 5.8e-39 133.2 0.2 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 ETO23240.1 - 1.2e-06 28.4 0.0 2.6e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 ETO23240.1 - 7.4e-06 25.6 0.1 3.3e-05 23.5 0.0 2.1 3 0 0 3 3 3 1 Part of AAA domain PhoH PF02562.11 ETO23240.1 - 8.3e-05 21.9 0.1 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA_30 PF13604.1 ETO23240.1 - 0.0001 21.9 0.0 0.00027 20.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.1 ETO23240.1 - 0.00046 19.3 0.1 0.00093 18.3 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Helicase_RecD PF05127.9 ETO23240.1 - 0.0022 17.6 0.0 0.0037 16.9 0.0 1.3 1 0 0 1 1 1 1 Helicase AAA_22 PF13401.1 ETO23240.1 - 0.0098 16.0 0.0 0.023 14.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 ETO23240.1 - 0.087 12.5 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain ARS2 PF04959.8 ETO23241.1 - 1.4e-08 35.2 1.7 1.4e-08 35.2 1.1 2.2 2 0 0 2 2 2 1 Arsenite-resistance protein 2 DUF4187 PF13821.1 ETO23241.1 - 5.2e-07 29.1 1.8 1.4e-06 27.8 1.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) RRM_1 PF00076.17 ETO23241.1 - 0.015 14.9 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YfhO PF09586.5 ETO23241.1 - 0.054 11.5 0.3 0.1 10.5 0.2 1.4 1 0 0 1 1 1 0 Bacterial membrane protein YfhO RRM_6 PF14259.1 ETO23241.1 - 0.074 13.0 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3546 PF12066.3 ETO23242.1 - 1.4e-06 28.2 3.2 1.4e-06 28.2 2.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) Exo_endo_phos PF03372.18 ETO23243.1 - 7.8e-08 32.5 0.0 8.5e-08 32.4 0.0 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 ETO23243.1 - 0.024 14.2 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase USP8_dimer PF08969.6 ETO23245.1 - 0.033 14.1 0.1 0.061 13.2 0.1 1.5 1 0 0 1 1 1 0 USP8 dimerisation domain Epimerase PF01370.16 ETO23246.1 - 6.1e-23 81.4 0.2 3.5e-22 79.0 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETO23246.1 - 6.6e-21 74.2 0.0 8.3e-21 73.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 ETO23246.1 - 7.4e-15 55.4 0.0 1.3e-14 54.5 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 ETO23246.1 - 1.3e-13 50.4 0.2 4.1e-13 48.8 0.1 1.7 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 ETO23246.1 - 1.2e-09 38.0 0.0 2.2e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 ETO23246.1 - 2.3e-09 37.3 0.1 5e-09 36.2 0.0 1.6 2 1 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 ETO23246.1 - 5.2e-09 35.7 0.0 2e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 ETO23246.1 - 0.00012 21.1 0.0 0.00019 20.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF2016 PF09436.5 ETO23246.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2016) Nt_Gln_amidase PF09764.4 ETO23247.1 - 7.3e-31 106.8 0.0 8.9e-31 106.6 0.0 1.1 1 0 0 1 1 1 1 N-terminal glutamine amidase DUF573 PF04504.9 ETO23247.1 - 0.076 13.3 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF573 G-alpha PF00503.15 ETO23248.1 - 0.00027 19.7 2.1 0.002 16.8 1.5 2.1 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO23248.1 - 0.0013 18.0 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SF-assemblin PF06705.6 ETO23249.1 - 0.00044 19.4 42.6 0.0071 15.5 15.8 2.3 1 1 1 2 2 2 2 SF-assemblin/beta giardin BBP1_C PF15272.1 ETO23249.1 - 0.00061 19.4 15.5 0.00061 19.4 10.7 4.3 1 1 3 4 4 4 1 Spindle pole body component BBP1, C-terminal Pox_A_type_inc PF04508.7 ETO23249.1 - 0.63 9.9 0.1 0.63 9.9 0.0 6.0 5 1 0 5 5 5 0 Viral A-type inclusion protein repeat GP41 PF00517.12 ETO23249.1 - 0.82 9.1 32.9 1.6 8.2 0.9 5.1 3 2 2 5 5 5 0 Retroviral envelope protein Baculo_PEP_C PF04513.7 ETO23249.1 - 1.4 8.7 10.3 2.1 8.1 0.6 3.2 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mnd1 PF03962.10 ETO23249.1 - 2.4 7.7 49.4 0.23 11.1 9.2 3.4 1 1 1 3 3 3 0 Mnd1 family AAA_13 PF13166.1 ETO23249.1 - 2.6 6.4 46.5 0.3 9.4 14.8 2.9 1 1 2 3 3 3 0 AAA domain PilJ PF13675.1 ETO23249.1 - 2.8 8.3 18.9 0.95 9.7 3.4 3.8 2 2 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Tup_N PF08581.5 ETO23249.1 - 4.3 7.5 35.8 0.23 11.6 7.3 4.3 3 2 1 4 4 4 0 Tup N-terminal DUF3584 PF12128.3 ETO23249.1 - 5.7 4.1 48.3 18 2.4 3.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) TMF_TATA_bd PF12325.3 ETO23249.1 - 7.4 6.3 46.9 0.11 12.2 10.3 4.2 2 2 1 4 4 4 0 TATA element modulatory factor 1 TATA binding ATG22 PF11700.3 ETO23250.1 - 8.4e-29 100.3 10.1 5e-22 78.0 6.4 2.1 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like Jacalin PF01419.12 ETO23250.1 - 0.00032 20.5 0.1 0.00092 19.1 0.0 1.8 2 0 0 2 2 2 1 Jacalin-like lectin domain DUF3938 PF13074.1 ETO23250.1 - 0.12 12.2 4.8 0.11 12.3 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) ATG22 PF11700.3 ETO23251.1 - 0.00075 18.0 0.0 0.00081 17.9 0.0 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like DUF912 PF06024.7 ETO23251.1 - 7.2 6.7 7.2 2.3 8.2 3.1 1.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2207 PF09972.4 ETO23252.1 - 0.071 11.6 1.2 0.087 11.4 0.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1700 PF08006.6 ETO23252.1 - 0.15 11.3 12.7 0.21 10.8 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Tic20 PF09685.5 ETO23252.1 - 0.31 11.0 12.7 0.5 10.3 8.8 1.3 1 0 0 1 1 1 0 Tic20-like protein Phlebovirus_G1 PF07243.6 ETO23252.1 - 2.8 5.9 10.3 5.2 5.0 7.2 1.3 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 DUF2628 PF10947.3 ETO23252.1 - 3.3 7.5 6.2 4.9 6.9 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) DUF2614 PF11023.3 ETO23252.1 - 4 7.2 8.7 6.6 6.5 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2614) Helicase_C PF00271.26 ETO23254.1 - 1.7e-20 72.6 0.1 3.8e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETO23254.1 - 1.3e-08 34.5 0.0 2.6e-06 27.0 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Ycf1 PF05758.7 ETO23256.1 - 0.00076 17.3 2.4 0.0012 16.7 1.6 1.2 1 0 0 1 1 1 1 Ycf1 DUF1510 PF07423.6 ETO23256.1 - 0.0022 17.3 12.9 0.0022 17.3 8.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) IncA PF04156.9 ETO23256.1 - 0.09 12.3 0.8 0.14 11.7 0.6 1.2 1 0 0 1 1 1 0 IncA protein ETRAMP PF09716.5 ETO23256.1 - 0.11 12.5 2.7 0.91 9.5 0.2 2.5 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) RNA_pol_3_Rpc31 PF11705.3 ETO23256.1 - 0.34 10.8 19.1 0.64 9.9 13.2 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Peptidase_S49_N PF08496.5 ETO23256.1 - 0.38 10.5 9.6 0.029 14.1 3.1 1.6 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF4011 PF13195.1 ETO23256.1 - 0.48 10.4 7.8 0.85 9.6 5.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) TRAP_alpha PF03896.11 ETO23256.1 - 1.8 7.4 10.6 3.6 6.4 7.4 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Vfa1 PF08432.5 ETO23256.1 - 2.4 8.1 25.3 0.047 13.7 12.1 1.8 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 RNA_polI_A34 PF08208.6 ETO23256.1 - 2.8 7.5 22.8 0.022 14.4 10.1 1.6 2 0 0 2 2 1 0 DNA-directed RNA polymerase I subunit RPA34.5 NARP1 PF12569.3 ETO23256.1 - 3.2 6.3 18.4 4.8 5.8 12.7 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RXT2_N PF08595.6 ETO23256.1 - 4.7 6.9 17.2 7.8 6.2 9.8 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal ANAPC15 PF15243.1 ETO23256.1 - 5.1 7.2 26.0 0.23 11.5 13.8 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Herpes_LMP1 PF05297.6 ETO23257.1 - 0.018 13.9 0.0 0.018 13.9 0.0 2.4 3 0 0 3 3 3 0 Herpesvirus latent membrane protein 1 (LMP1) DUF4381 PF14316.1 ETO23257.1 - 0.04 14.0 0.3 0.04 14.0 0.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4381) CoA_binding_3 PF13727.1 ETO23257.1 - 0.051 13.4 2.7 0.17 11.6 0.2 2.5 2 1 1 3 3 3 0 CoA-binding domain Potass_KdpF PF09604.5 ETO23257.1 - 0.93 9.4 4.6 2.9 7.8 3.2 1.8 1 0 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) WD40 PF00400.27 ETO23258.1 - 4.6e-10 38.9 2.8 1.5e-09 37.3 1.1 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO23258.1 - 0.0056 14.8 0.2 0.0093 14.1 0.1 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 DUF4119 PF13494.1 ETO23259.1 - 0.022 14.7 0.1 0.022 14.7 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) SecA_SW PF07516.8 ETO23259.1 - 0.045 13.5 0.1 0.045 13.5 0.1 1.8 2 0 0 2 2 2 0 SecA Wing and Scaffold domain DUF2738 PF10927.3 ETO23259.1 - 0.44 9.5 3.5 0.75 8.7 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2738) NAM-associated PF14303.1 ETO23259.1 - 5.2 7.3 17.5 7 6.9 12.1 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain zf-RanBP PF00641.13 ETO23260.1 - 0.0002 20.3 15.7 0.032 13.3 0.3 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.10 ETO23260.1 - 0.0064 16.0 0.4 0.0064 16.0 0.3 3.1 2 1 1 3 3 3 2 Sec23/Sec24 zinc finger TFIIA PF03153.8 ETO23261.1 - 0.0012 18.8 54.0 0.0012 18.8 37.4 2.0 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 ETO23261.1 - 0.29 9.3 88.9 0.43 8.7 61.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SID-1_RNA_chan PF13965.1 ETO23261.1 - 0.62 8.1 18.0 1.1 7.3 12.5 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 HCO3_cotransp PF00955.16 ETO23261.1 - 2.1 6.9 6.8 3.3 6.2 4.7 1.4 1 0 0 1 1 1 0 HCO3- transporter family VWA PF00092.23 ETO23262.1 - 2.2e-06 27.4 0.4 0.00071 19.3 0.0 2.4 2 1 0 2 2 2 2 von Willebrand factor type A domain HYR PF02494.11 ETO23262.1 - 0.11 12.4 0.0 0.4 10.7 0.0 1.9 2 0 0 2 2 2 0 HYR domain DUF2146 PF10220.4 ETO23264.1 - 9.4e-52 176.1 13.6 4.7e-30 104.3 6.3 4.2 3 1 1 4 4 4 3 Uncharacterized conserved protein (DUF2146) LRR19-TM PF15176.1 ETO23264.1 - 0.03 13.9 0.2 0.17 11.5 0.0 2.3 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain DUF2422 PF10337.4 ETO23264.1 - 0.15 10.7 0.9 0.31 9.7 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Baculo_11_kDa PF06143.6 ETO23266.1 - 0.016 14.5 4.0 1.6 8.1 0.9 2.9 2 0 0 2 2 2 0 Baculovirus 11 kDa family DUF1183 PF06682.7 ETO23266.1 - 0.026 14.1 0.8 0.045 13.3 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) Neur_chan_memb PF02932.11 ETO23266.1 - 0.18 11.6 7.2 0.42 10.4 5.0 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region IncA PF04156.9 ETO23266.1 - 0.18 11.3 1.6 0.27 10.7 0.1 2.1 2 0 0 2 2 2 0 IncA protein ATP-synt_8 PF00895.15 ETO23266.1 - 0.97 9.6 10.7 5.4 7.3 0.0 4.3 4 0 0 4 4 4 0 ATP synthase protein 8 PT PF04886.7 ETO23267.1 - 4.3 6.7 15.5 8.3 5.8 10.8 1.4 1 0 0 1 1 1 0 PT repeat Zip PF02535.17 ETO23268.1 - 3.2 6.6 9.0 22 3.9 6.3 2.0 1 1 0 1 1 1 0 ZIP Zinc transporter TRAM_LAG1_CLN8 PF03798.11 ETO23269.1 - 3.1e-11 43.1 19.2 8.3e-11 41.8 13.3 1.7 1 1 0 1 1 1 1 TLC domain FerI PF08151.7 ETO23270.1 - 0.12 12.3 0.4 3.5 7.7 0.0 2.8 3 0 0 3 3 3 0 FerI (NUC094) domain HlyIII PF03006.15 ETO23271.1 - 1.8e-25 89.6 13.7 1.8e-25 89.6 9.5 1.6 2 0 0 2 2 2 1 Haemolysin-III related Kei1 PF08552.6 ETO23271.1 - 2.8e-05 23.8 6.7 0.067 12.8 0.0 2.6 2 0 0 2 2 2 2 Inositolphosphorylceramide synthase subunit Kei1 ETRAMP PF09716.5 ETO23271.1 - 0.0074 16.2 0.9 0.028 14.3 0.6 2.0 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) E1-E2_ATPase PF00122.15 ETO23272.1 - 2e-29 102.2 1.4 1.9e-28 99.0 0.1 2.0 1 1 1 2 2 2 2 E1-E2 ATPase Cation_ATPase_N PF00690.21 ETO23272.1 - 1.1e-13 50.3 6.1 1e-07 31.2 0.4 3.0 3 0 0 3 3 3 2 Cation transporter/ATPase, N-terminus BacA PF02673.13 ETO23272.1 - 0.024 13.8 0.1 0.034 13.3 0.1 1.2 1 0 0 1 1 1 0 Bacitracin resistance protein BacA zf-RING_2 PF13639.1 ETO23273.1 - 2e-06 27.5 7.9 2e-06 27.5 5.5 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO23273.1 - 1.2e-05 25.1 9.9 2.3e-05 24.3 6.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 ETO23273.1 - 0.00031 20.4 6.1 0.0012 18.4 4.2 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 ETO23273.1 - 0.00034 20.2 10.3 0.0013 18.4 7.1 2.1 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 ETO23273.1 - 0.00058 19.4 10.7 0.00058 19.4 7.4 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 ETO23273.1 - 0.00089 19.0 10.7 0.0014 18.4 6.5 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 ETO23273.1 - 0.055 13.2 3.2 0.15 11.8 2.2 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Pigment_DH PF06324.6 ETO23273.1 - 0.16 11.2 2.0 0.29 10.4 1.4 1.4 1 0 0 1 1 1 0 Pigment-dispersing hormone (PDH) Transp_Tc5_C PF04236.10 ETO23273.1 - 0.18 12.0 7.2 0.52 10.5 5.0 1.7 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain zf-MIZ PF02891.15 ETO23273.1 - 0.33 10.5 7.2 0.86 9.1 5.0 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_4 PF14570.1 ETO23273.1 - 0.47 10.0 15.1 0.045 13.3 5.7 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Elf1 PF05129.8 ETO23273.1 - 2.5 7.8 14.3 7 6.4 9.9 1.8 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Prok-RING_4 PF14447.1 ETO23273.1 - 3.4 7.2 10.4 4.9 6.7 4.6 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 FA_desaturase PF00487.19 ETO23276.1 - 0.0012 18.3 7.1 0.0012 18.3 4.9 2.1 1 1 1 2 2 2 2 Fatty acid desaturase Anticodon_1 PF08264.8 ETO23277.1 - 1.9e-28 99.1 0.0 1.8e-27 96.0 0.0 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA CS PF04969.11 ETO23278.1 - 0.00019 21.8 3.9 0.00039 20.9 1.7 2.3 2 0 0 2 2 2 1 CS domain Rhodanese PF00581.15 ETO23279.1 - 9.2e-24 83.9 0.1 4.2e-08 33.5 0.0 3.2 3 0 0 3 3 3 3 Rhodanese-like domain TFIIA PF03153.8 ETO23281.1 - 0.65 9.8 11.9 0.82 9.4 8.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BAF1_ABF1 PF04684.8 ETO23281.1 - 2.2 7.0 6.0 3 6.5 4.2 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF973 PF06157.6 ETO23282.1 - 0.042 12.8 1.2 0.049 12.5 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF788 PF05620.6 ETO23282.1 - 0.58 10.0 2.7 0.27 11.0 0.4 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF788) WD40 PF00400.27 ETO23283.1 - 1.1e-08 34.6 1.9 0.00057 19.6 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat Imm43 PF15602.1 ETO23283.1 - 0.087 12.7 1.8 0.16 11.9 1.3 1.5 1 0 0 1 1 1 0 Immunity protein 43 Folliculin PF11704.3 ETO23283.1 - 0.09 12.3 3.5 1 8.9 0.1 2.3 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport FlxA PF14282.1 ETO23283.1 - 0.091 12.7 18.0 0.22 11.5 5.5 2.3 2 0 0 2 2 2 0 FlxA-like protein DASH_Dad3 PF08656.5 ETO23283.1 - 0.44 10.2 9.5 2.3 7.9 1.3 2.5 2 0 0 2 2 2 0 DASH complex subunit Dad3 GvpL_GvpF PF06386.6 ETO23283.1 - 0.71 9.4 6.9 1.1 8.7 4.8 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF HCMV_UL139 PF12507.3 ETO23283.1 - 1.1 9.3 4.8 12 6.0 1.3 2.7 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein DUF3886 PF13025.1 ETO23283.1 - 1.8 8.5 17.0 0.091 12.7 7.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) Occludin_ELL PF07303.8 ETO23283.1 - 2.1 9.1 7.4 6.1 7.6 1.5 2.3 2 0 0 2 2 2 0 Occludin homology domain AAA_13 PF13166.1 ETO23283.1 - 2.2 6.6 14.1 2.7 6.3 9.8 1.1 1 0 0 1 1 1 0 AAA domain 60KD_IMP PF02096.15 ETO23283.1 - 5.2 6.6 9.4 0.67 9.5 1.9 2.2 2 1 0 2 2 2 0 60Kd inner membrane protein Transposase_22 PF02994.9 ETO23283.1 - 7.7 4.8 12.0 2.1 6.7 5.1 2.0 1 1 1 2 2 2 0 L1 transposable element Sas10_Utp3 PF04000.10 ETO23283.1 - 8 6.7 10.2 0.76 10.0 1.8 2.6 2 1 0 2 2 2 0 Sas10/Utp3/C1D family SlyX PF04102.7 ETO23283.1 - 8.6 6.8 8.8 15 6.0 2.0 2.8 2 1 1 3 3 3 0 SlyX Tropomyosin_1 PF12718.2 ETO23283.1 - 9.7 6.0 27.7 0.74 9.6 2.0 2.4 3 0 0 3 3 2 0 Tropomyosin like HALZ PF02183.13 ETO23284.1 - 0.00072 19.2 107.3 0.017 14.8 1.7 15.4 10 4 6 16 16 16 8 Homeobox associated leucine zipper V-SNARE PF05008.10 ETO23284.1 - 0.001 19.1 12.1 0.001 19.1 8.4 8.9 8 4 3 11 11 11 1 Vesicle transport v-SNARE protein N-terminus TPR_12 PF13424.1 ETO23286.1 - 3.3e-19 68.6 0.2 6.9e-15 54.7 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO23286.1 - 2.5e-13 49.4 4.3 1.7e-07 30.8 0.5 2.6 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETO23286.1 - 1.4e-10 40.3 4.3 0.00068 19.1 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat Kelch_6 PF13964.1 ETO23286.1 - 1.6e-10 40.6 0.3 0.00068 19.6 0.0 3.9 3 1 1 4 4 4 2 Kelch motif TPR_2 PF07719.12 ETO23286.1 - 6.1e-10 38.2 3.7 0.0088 15.8 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO23286.1 - 3.8e-08 32.5 5.6 0.021 14.5 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO23286.1 - 5.4e-07 28.9 1.6 0.013 15.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO23286.1 - 3.1e-05 23.7 0.1 0.012 15.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Kelch_1 PF01344.20 ETO23286.1 - 0.00013 21.3 8.3 0.0017 17.8 0.0 3.4 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO23286.1 - 0.0024 17.5 0.3 2.5 8.0 0.0 3.1 2 0 0 2 2 2 1 Kelch motif TPR_16 PF13432.1 ETO23286.1 - 0.0047 17.5 0.0 0.058 14.0 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat Kelch_4 PF13418.1 ETO23286.1 - 0.032 13.9 0.0 1.1 9.0 0.0 3.1 4 0 0 4 4 3 0 Galactose oxidase, central domain Flagellin_C PF00700.16 ETO23286.1 - 0.034 14.2 0.0 0.07 13.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region TPR_17 PF13431.1 ETO23286.1 - 0.038 14.2 0.2 3.8 7.9 0.0 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO23286.1 - 0.047 14.1 0.2 77 4.0 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETO23286.1 - 0.14 12.8 0.1 1.2e+02 3.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Kelch_5 PF13854.1 ETO23286.1 - 0.56 10.2 4.8 8.2 6.5 0.0 4.2 5 0 0 5 5 3 0 Kelch motif MIT PF04212.13 ETO23286.1 - 0.77 9.6 4.5 4.1 7.3 0.0 3.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain WD40 PF00400.27 ETO23287.1 - 5.5e-76 247.9 26.2 5.7e-15 54.5 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO23287.1 - 2.2e-07 29.4 10.9 0.056 11.5 2.2 4.7 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO23287.1 - 7.4e-06 24.4 0.5 0.016 13.5 0.0 2.6 1 1 1 3 3 3 2 Cytochrome D1 heme domain Resistin PF06954.6 ETO23287.1 - 9.2e-05 22.6 8.4 3.3 8.0 0.1 5.2 2 2 2 5 5 5 1 Resistin Nucleoporin_N PF08801.6 ETO23287.1 - 0.0043 15.8 13.9 0.2 10.3 0.6 5.0 1 1 2 4 4 4 3 Nup133 N terminal like Coatomer_WDAD PF04053.9 ETO23287.1 - 0.012 14.4 2.5 6.1 5.5 0.6 2.9 1 1 2 3 3 3 0 Coatomer WD associated region PD40 PF07676.7 ETO23287.1 - 0.12 12.0 0.0 19 5.0 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 ETO23288.1 - 2.4e-81 264.9 19.4 2.5e-13 49.3 0.0 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO23288.1 - 6.7e-11 42.2 0.2 1.7e-07 31.1 0.1 3.1 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO23288.1 - 7.1e-09 34.3 1.8 0.18 9.9 0.0 4.6 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO23288.1 - 3.1e-06 26.2 6.8 0.29 9.8 0.3 4.3 1 1 3 4 4 4 3 Nup133 N terminal like PD40 PF07676.7 ETO23288.1 - 1.3e-05 24.7 9.1 4.8 6.9 0.1 6.3 7 0 0 7 7 6 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO23288.1 - 0.00037 20.0 0.0 0.016 14.6 0.0 2.6 1 1 0 1 1 1 1 PQQ-like domain DUF1258 PF06869.7 ETO23288.1 - 0.0013 17.9 0.4 3.5 6.6 0.0 3.6 2 1 2 4 4 4 2 Protein of unknown function (DUF1258) Str_synth PF03088.11 ETO23288.1 - 0.0029 17.5 0.0 2 8.5 0.0 3.8 4 1 0 4 4 4 1 Strictosidine synthase Resistin PF06954.6 ETO23288.1 - 0.0064 16.7 0.0 7.3 6.9 0.0 4.0 3 1 1 4 4 4 1 Resistin Cytochrom_D1 PF02239.11 ETO23288.1 - 0.0075 14.6 0.1 0.28 9.4 0.0 2.8 1 1 1 2 2 2 2 Cytochrome D1 heme domain DUF4221 PF13970.1 ETO23288.1 - 0.0081 15.5 1.1 8.1 5.6 0.0 3.7 1 1 1 2 2 2 2 Domain of unknown function (DUF4221) Nbas_N PF15492.1 ETO23288.1 - 0.017 14.2 0.7 6.4 5.7 0.0 3.1 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal DUF2415 PF10313.4 ETO23288.1 - 0.073 12.7 0.0 2.6 7.8 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) AcetylCoA_hyd_C PF13336.1 ETO23288.1 - 0.11 12.1 0.0 5.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Acetyl-CoA hydrolase/transferase C-terminal domain Pkinase PF00069.20 ETO23289.1 - 4.2e-24 85.0 2.5 3.2e-20 72.3 0.1 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO23289.1 - 2.9e-14 52.7 0.7 1.1e-13 50.8 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 ETO23289.1 - 2.7e-06 26.6 0.6 6.8e-06 25.2 0.4 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Daxx PF03344.10 ETO23289.1 - 0.0076 14.7 33.8 0.0097 14.4 23.4 1.0 1 0 0 1 1 1 1 Daxx Family APH PF01636.18 ETO23289.1 - 0.048 13.3 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 ETO23289.1 - 0.065 12.1 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Utp14 PF04615.8 ETO23289.1 - 5.2 5.1 42.0 6.6 4.7 29.1 1.1 1 0 0 1 1 1 0 Utp14 protein G-alpha PF00503.15 ETO23290.1 - 3.6e-49 167.4 9.9 5.2e-49 166.9 6.8 1.2 1 0 0 1 1 1 1 G-protein alpha subunit AAA_17 PF13207.1 ETO23290.1 - 8.5e-06 26.5 0.8 0.0002 22.1 0.1 2.8 2 1 0 2 2 2 1 AAA domain Arf PF00025.16 ETO23290.1 - 1.3e-05 24.5 0.6 0.015 14.5 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETO23290.1 - 0.00078 19.3 1.4 0.081 12.8 0.9 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.1 ETO23290.1 - 0.0029 17.8 0.4 0.0094 16.2 0.2 1.9 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 ETO23290.1 - 0.0031 17.0 0.0 0.0054 16.2 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.1 ETO23290.1 - 0.0047 16.4 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 ETO23290.1 - 0.0056 16.9 0.3 0.012 15.8 0.2 1.7 1 1 0 1 1 1 1 ABC transporter AAA_33 PF13671.1 ETO23290.1 - 0.008 16.0 0.5 0.2 11.5 0.1 2.7 2 1 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.12 ETO23290.1 - 0.019 14.5 0.1 0.2 11.1 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Miro PF08477.8 ETO23290.1 - 0.022 15.2 1.3 0.16 12.4 0.3 2.6 2 1 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 ETO23290.1 - 0.036 13.8 0.1 0.081 12.7 0.0 1.7 1 1 0 1 1 1 0 Dynamin family DUF87 PF01935.12 ETO23290.1 - 0.036 13.8 0.1 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF258 PF03193.11 ETO23290.1 - 0.041 13.0 0.0 0.075 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 ETO23290.1 - 0.042 13.4 0.2 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 ETO23290.1 - 0.047 13.1 0.0 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Mg_chelatase PF01078.16 ETO23290.1 - 0.049 12.7 0.1 0.18 10.9 0.0 1.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 ETO23290.1 - 0.072 13.0 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 ETO23290.1 - 0.094 12.8 0.0 0.38 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 ETO23290.1 - 4.9 7.4 7.0 4 7.6 0.0 2.9 2 1 0 2 2 2 0 AAA domain Herpes_capsid PF06112.6 ETO23291.1 - 0.0088 16.0 5.5 0.013 15.5 3.8 1.5 1 0 0 1 1 1 1 Gammaherpesvirus capsid protein Period_C PF12114.3 ETO23291.1 - 0.11 12.0 7.1 0.19 11.2 4.9 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Macoilin PF09726.4 ETO23291.1 - 1.9 6.7 9.1 2 6.6 6.3 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF77 PF01910.12 ETO23292.1 - 2.4e-29 100.8 0.0 3.3e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF77 Ykof PF07615.6 ETO23292.1 - 0.055 13.6 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 YKOF-related Family PH PF00169.24 ETO23294.1 - 3.3e-05 24.0 0.1 4.1e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 ETO23294.1 - 0.0012 18.9 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain Nodulin_late PF07127.6 ETO23294.1 - 0.12 12.5 0.4 0.12 12.5 0.3 1.6 2 0 0 2 2 2 0 Late nodulin protein DSS1_SEM1 PF05160.8 ETO23295.1 - 2.6e-05 23.8 24.7 0.00086 19.0 17.1 2.2 1 1 0 1 1 1 1 DSS1/SEM1 family Syntaxin-6_N PF09177.6 ETO23296.1 - 0.0096 16.3 2.5 0.0096 16.3 1.7 3.0 2 1 1 3 3 3 1 Syntaxin 6, N-terminal NPV_P10 PF05531.7 ETO23296.1 - 0.011 15.9 3.9 0.033 14.4 1.1 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 ETO23296.1 - 0.015 15.1 1.3 0.59 9.9 0.3 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CALCOCO1 PF07888.6 ETO23296.1 - 0.018 13.3 6.0 0.019 13.2 4.2 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like RGS-like PF09128.6 ETO23296.1 - 0.046 13.2 7.6 0.22 10.9 3.1 2.3 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain DUF3584 PF12128.3 ETO23296.1 - 0.091 10.0 14.6 0.0038 14.6 6.4 1.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_13 PF13166.1 ETO23296.1 - 0.78 8.1 16.5 0.25 9.7 8.5 2.1 1 1 0 1 1 1 0 AAA domain FlaC_arch PF05377.6 ETO23296.1 - 0.93 9.4 6.3 3.1 7.7 0.2 3.1 2 1 0 3 3 3 0 Flagella accessory protein C (FlaC) BCDHK_Adom3 PF10436.4 ETO23296.1 - 0.94 8.9 8.4 40 3.6 5.6 2.3 1 1 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DUF342 PF03961.8 ETO23296.1 - 1.6 7.0 8.7 2.8 6.2 6.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 ETO23296.1 - 1.8 8.0 16.5 0.83 9.2 9.9 1.6 2 0 0 2 2 2 0 IncA protein Atg14 PF10186.4 ETO23296.1 - 2.2 7.1 14.9 2.2 7.1 9.0 1.9 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1342 PF07072.6 ETO23296.1 - 2.5 7.7 10.0 0.31 10.6 2.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1342) DUF4047 PF13256.1 ETO23296.1 - 2.5 8.0 15.4 1.9 8.4 5.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4047) DUF948 PF06103.6 ETO23296.1 - 3.3 7.6 9.1 16 5.4 0.1 3.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) V_ATPase_I PF01496.14 ETO23296.1 - 4.3 5.0 12.3 5.8 4.6 8.2 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family LUC7 PF03194.10 ETO23296.1 - 7 6.0 11.8 11 5.5 6.9 1.8 1 1 1 2 2 2 0 LUC7 N_terminus ORC5_C PF14630.1 ETO23297.1 - 1.4e-28 100.1 8.1 2.8e-27 95.8 5.6 2.2 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 ETO23297.1 - 7.6e-07 29.2 0.0 1.8e-05 24.8 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 ETO23297.1 - 0.00046 19.9 0.0 0.00046 19.9 0.0 2.8 3 1 0 3 3 3 1 Archaeal ATPase AAA_22 PF13401.1 ETO23297.1 - 0.0016 18.5 0.0 0.017 15.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 ETO23297.1 - 0.0061 16.7 0.1 0.044 13.9 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 ETO23297.1 - 0.014 15.8 2.0 0.074 13.5 0.0 2.8 2 1 1 3 3 3 0 Miro-like protein AAA_14 PF13173.1 ETO23297.1 - 0.021 14.7 0.9 0.65 9.9 0.0 3.2 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 ETO23297.1 - 0.037 13.9 0.0 0.092 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 ETO23297.1 - 0.089 12.5 0.0 0.55 10.0 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain AAA_17 PF13207.1 ETO23297.1 - 0.11 13.2 0.2 0.75 10.6 0.0 2.4 2 2 1 3 3 2 0 AAA domain AAA_28 PF13521.1 ETO23297.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 ETO23297.1 - 0.61 9.6 6.7 5 6.6 4.7 2.2 1 1 0 1 1 1 0 AAA domain POX PF07526.6 ETO23299.1 - 0.063 13.5 2.2 0.6 10.3 0.1 2.7 3 0 0 3 3 3 0 Associated with HOX Sigma70_ner PF04546.8 ETO23299.1 - 0.51 9.9 9.4 1.1 8.8 4.3 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF506 PF04720.7 ETO23299.1 - 4.6 6.7 7.6 7.3 6.1 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF506) DUF3359 PF11839.3 ETO23300.1 - 0.065 13.5 0.9 0.065 13.5 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3359) Mucin PF01456.12 ETO23300.1 - 1.1 9.0 25.6 0.11 12.3 14.2 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein Rubella_E2 PF05749.6 ETO23300.1 - 4.2 6.5 5.9 6 6.0 4.1 1.2 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 SSP160 PF06933.6 ETO23300.1 - 5.9 4.7 20.0 9.2 4.1 13.8 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 HEAT_2 PF13646.1 ETO23301.1 - 0.044 14.0 0.4 1.4 9.2 0.0 3.2 3 0 0 3 3 3 0 HEAT repeats Laminin_G_3 PF13385.1 ETO23302.1 - 5.2e-05 23.5 0.0 0.00012 22.3 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4565 PF15127.1 ETO23303.1 - 4 7.8 5.5 9.7 6.6 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF4565) tRNA-synt_1g PF09334.6 ETO23305.1 - 7.8e-10 37.9 0.2 2e-08 33.2 0.0 2.2 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 ETO23305.1 - 5.9e-09 34.4 0.1 2.1e-08 32.6 0.1 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 ETO23305.1 - 1.3e-07 31.0 0.0 2.6e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DUF2497 PF10691.4 ETO23306.1 - 4.2e-10 39.4 1.4 4.2e-10 39.4 1.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2497) RasGAP PF00616.14 ETO23308.1 - 2.2e-11 43.8 2.5 2.2e-11 43.8 1.7 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CDC45 PF02724.9 ETO23308.1 - 0.4 8.6 26.4 0.77 7.7 18.3 1.4 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 ETO23308.1 - 1.2 6.9 39.7 0.14 10.0 22.5 2.2 2 0 0 2 2 2 0 Nop14-like family Zip PF02535.17 ETO23308.1 - 1.5 7.7 5.2 0.085 11.8 0.2 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter RNA_pol_3_Rpc31 PF11705.3 ETO23308.1 - 1.6 8.6 34.5 0.066 13.1 17.6 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2457 PF10446.4 ETO23308.1 - 4.5 5.8 33.2 8.6 4.9 23.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CobT PF06213.7 ETO23308.1 - 9.7 5.2 25.6 17 4.4 17.8 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Anoctamin PF04547.7 ETO23309.1 - 4.4e-48 164.0 10.3 5.6e-48 163.7 7.1 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF2975 PF11188.3 ETO23309.1 - 2.9 7.6 7.8 4.1 7.1 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Anoctamin PF04547.7 ETO23310.1 - 1.5e-47 162.3 0.2 1.7e-47 162.1 0.2 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Kinesin PF00225.18 ETO23312.1 - 1.3e-09 37.2 0.0 1.8e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain SAM_1 PF00536.25 ETO23312.1 - 7.5e-06 26.0 0.0 1.4e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO23312.1 - 1e-05 25.2 0.0 1.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ste50p-SAM PF09235.5 ETO23312.1 - 0.091 12.8 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Kinesin PF00225.18 ETO23313.1 - 8.6e-68 228.4 0.6 8.6e-68 228.4 0.4 2.1 2 1 1 3 3 3 1 Kinesin motor domain DUF1786 PF08735.5 ETO23313.1 - 0.00069 18.8 0.1 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 Putative pyruvate format-lyase activating enzyme (DUF1786) Maelstrom PF13017.1 ETO23313.1 - 0.025 14.0 0.9 0.069 12.6 0.0 2.0 2 0 0 2 2 2 0 piRNA pathway germ-plasm component Rad52_Rad22 PF04098.10 ETO23313.1 - 0.034 13.8 3.2 0.035 13.8 0.1 2.2 2 0 0 2 2 2 0 Rad52/22 family double-strand break repair protein FHA PF00498.21 ETO23313.1 - 0.083 13.0 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 FHA domain DUF1636 PF07845.6 ETO23313.1 - 0.14 12.3 1.4 0.34 11.1 0.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1636) Ribosomal_L29 PF00831.18 ETO23313.1 - 0.76 9.5 13.9 0.042 13.5 1.4 4.3 3 1 1 4 4 4 0 Ribosomal L29 protein LOH1CR12 PF10158.4 ETO23314.1 - 0.0025 17.6 0.3 0.0043 16.8 0.2 1.3 1 0 0 1 1 1 1 Tumour suppressor protein PH PF00169.24 ETO23314.1 - 0.045 13.9 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 PH domain RabGAP-TBC PF00566.13 ETO23315.1 - 1.5e-18 67.0 7.0 2.6e-18 66.2 4.9 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain WBS_methylT PF12589.3 ETO23316.1 - 0.025 15.0 2.7 0.025 15.0 1.9 3.1 3 0 0 3 3 3 0 Methyltransferase involved in Williams-Beuren syndrome Cathelicidins PF00666.12 ETO23316.1 - 0.082 13.0 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Cathelicidin ERp29 PF07749.7 ETO23316.1 - 0.76 10.4 9.7 0.14 12.8 4.2 1.6 2 0 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain STAT_int PF02865.12 ETO23317.1 - 0.077 12.9 0.4 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 STAT protein, protein interaction domain PROCN PF08083.6 ETO23318.1 - 0.0036 15.8 2.0 0.0036 15.8 1.4 1.0 1 0 0 1 1 1 1 PROCN (NUC071) domain SRI PF08236.6 ETO23318.1 - 1.1 9.1 10.0 1.7 8.6 6.9 1.2 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain zf-RING_2 PF13639.1 ETO23319.1 - 1.7e-05 24.5 4.0 1.7e-05 24.5 2.8 7.5 7 3 0 7 7 7 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO23319.1 - 0.00098 19.0 1.3 0.00098 19.0 0.9 8.7 8 3 1 9 9 9 2 Zinc finger, C3HC4 type (RING finger) Gelsolin PF00626.17 ETO23321.1 - 1.5e-31 107.8 0.1 7.8e-11 41.5 0.0 3.6 3 0 0 3 3 3 3 Gelsolin repeat Ras PF00071.17 ETO23324.1 - 3.3e-16 59.0 0.0 4.3e-16 58.7 0.0 1.2 1 1 0 1 1 1 1 Ras family Miro PF08477.8 ETO23324.1 - 0.0013 19.2 0.0 0.0025 18.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein HMG_box_5 PF14887.1 ETO23324.1 - 0.05 13.3 1.4 0.076 12.8 1.0 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box 5 WD40 PF00400.27 ETO23325.1 - 2.1e-16 59.0 1.8 1.7e-05 24.4 0.0 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat ZZ PF00569.12 ETO23326.1 - 8.5e-09 34.8 1.1 1.8e-08 33.7 0.8 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type TLD PF07534.11 ETO23327.1 - 0.011 15.6 0.1 0.021 14.8 0.1 1.5 1 0 0 1 1 1 0 TLD gerPA PF10676.4 ETO23327.1 - 2.9 7.8 4.8 2.7 7.8 0.6 2.4 2 0 0 2 2 2 0 Spore germination protein gerPA/gerPF Spin-Ssty PF02513.12 ETO23327.1 - 6.1 6.4 5.6 0.98 9.0 0.6 2.1 2 0 0 2 2 2 0 Spin/Ssty Family Neur_chan_memb PF02932.11 ETO23328.1 - 1.1 9.0 6.5 1.8 8.3 4.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAT1 PF09770.4 ETO23328.1 - 4.8 5.2 30.0 5.9 4.9 20.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HD-ZIP_N PF04618.7 ETO23328.1 - 6.5 7.3 10.8 1.9 9.0 4.8 1.9 1 1 1 2 2 2 0 HD-ZIP protein N terminus FLO_LFY PF01698.11 ETO23330.1 - 1.1 8.0 15.1 1.4 7.6 10.5 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Ycf1 PF05758.7 ETO23330.1 - 1.4 6.5 21.2 1.8 6.1 14.7 1.3 1 0 0 1 1 1 0 Ycf1 SDA1 PF05285.7 ETO23330.1 - 1.4 8.0 36.2 1.9 7.6 25.1 1.2 1 0 0 1 1 1 0 SDA1 MIP-T3 PF10243.4 ETO23330.1 - 3.3 6.0 37.0 4.5 5.6 25.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Asp-B-Hydro_N PF05279.6 ETO23330.1 - 5.1 6.8 33.1 6.7 6.4 23.0 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Spt5_N PF11942.3 ETO23331.1 - 0.86 10.2 28.8 0.17 12.5 9.6 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal CAP_GLY PF01302.20 ETO23332.1 - 6.2e-10 38.6 0.1 8.4e-10 38.2 0.1 1.2 1 0 0 1 1 1 1 CAP-Gly domain L_protein_N PF15518.1 ETO23332.1 - 0.029 13.7 0.2 0.035 13.4 0.1 1.1 1 0 0 1 1 1 0 L protein N-terminus Myc_target_1 PF15179.1 ETO23333.1 - 4.5e-05 23.1 1.0 7.3e-05 22.4 0.7 1.3 1 0 0 1 1 1 1 Myc target protein 1 MIP-T3 PF10243.4 ETO23333.1 - 0.00044 18.8 28.0 0.00061 18.3 19.4 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF1510 PF07423.6 ETO23333.1 - 0.0067 15.8 16.5 0.0067 15.8 11.4 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1510) BSP_II PF05432.6 ETO23333.1 - 0.021 14.1 24.5 0.03 13.6 17.0 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) 7tm_1 PF00001.16 ETO23333.1 - 0.021 13.9 0.1 0.035 13.2 0.0 1.4 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) ODV-E18 PF10717.4 ETO23333.1 - 0.027 13.8 4.9 0.093 12.1 3.4 2.0 1 1 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 PMP22_Claudin PF00822.15 ETO23333.1 - 0.035 13.7 0.1 0.066 12.8 0.1 1.4 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Brr6_like_C_C PF10104.4 ETO23333.1 - 0.056 12.9 2.0 0.076 12.5 0.7 1.7 2 0 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain CbtA PF09490.5 ETO23333.1 - 0.081 12.2 0.2 0.14 11.4 0.0 1.4 1 1 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) Utp14 PF04615.8 ETO23333.1 - 0.29 9.2 41.3 0.35 8.9 28.6 1.0 1 0 0 1 1 1 0 Utp14 protein DUF4446 PF14584.1 ETO23333.1 - 0.34 10.7 3.0 0.6 9.9 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF106 PF01956.11 ETO23333.1 - 1.2 8.6 7.4 0.057 12.9 0.9 1.9 1 1 1 2 2 2 0 Integral membrane protein DUF106 Plasmodium_Vir PF05795.6 ETO23333.1 - 2.9 6.9 29.1 0.018 14.2 10.1 2.1 1 1 1 2 2 2 0 Plasmodium vivax Vir protein DUF3246 PF11596.3 ETO23333.1 - 4 6.6 29.7 6.5 5.9 20.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) LRR_4 PF12799.2 ETO23334.1 - 5.2e-06 25.9 1.9 0.00041 19.9 0.4 2.8 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 ETO23334.1 - 1.3e-05 24.8 2.0 1.8e-05 24.4 0.8 1.6 1 1 1 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.1 ETO23334.1 - 0.2 11.4 2.6 0.58 9.9 0.6 2.4 2 0 0 2 2 2 0 Leucine rich repeat DUF4629 PF15442.1 ETO23336.1 - 8.7 6.4 12.1 1.6 8.8 3.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4629) WD40 PF00400.27 ETO23337.1 - 2.8e-20 71.3 10.8 7.3e-08 32.0 0.0 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.6 ETO23337.1 - 0.00041 20.1 0.2 0.003 17.3 0.0 2.4 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A DUF1361 PF07099.6 ETO23337.1 - 0.017 14.9 0.1 0.034 13.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1361) PABP PF00658.13 ETO23339.1 - 1.9e-05 24.2 0.0 3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain zf-C3HC4_3 PF13920.1 ETO23341.1 - 1.1e-09 37.7 8.8 1.1e-09 37.7 6.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO23341.1 - 0.0045 16.9 10.9 0.0045 16.9 7.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 ETO23341.1 - 0.011 15.3 5.4 0.028 13.9 3.8 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.1 ETO23341.1 - 0.013 15.1 10.0 0.035 13.8 7.0 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Zn_ribbon_2 PF12674.2 ETO23342.1 - 0.061 13.6 0.6 0.22 11.9 0.0 2.2 2 0 0 2 2 2 0 Putative zinc ribbon domain Nucleoplasmin PF03066.10 ETO23342.1 - 0.15 11.5 8.0 0.32 10.5 5.6 1.5 1 0 0 1 1 1 0 Nucleoplasmin DUF3807 PF12720.2 ETO23343.1 - 4.6 7.3 22.1 6.2 6.9 15.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Trypsin_2 PF13365.1 ETO23344.1 - 0.0019 18.1 0.6 0.0041 17.1 0.1 1.8 2 0 0 2 2 2 1 Trypsin-like peptidase domain PhoH PF02562.11 ETO23344.1 - 0.025 13.7 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein DUF1639 PF07797.9 ETO23344.1 - 0.11 11.9 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1639) Bac_Ubq_Cox PF01654.12 ETO23344.1 - 0.16 10.3 0.1 0.39 9.0 0.0 1.6 2 0 0 2 2 2 0 Bacterial Cytochrome Ubiquinol Oxidase Cyclin PF08613.6 ETO23345.1 - 1.1e-07 32.3 0.0 1.1e-07 32.3 0.0 2.2 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 ETO23345.1 - 0.00052 19.5 0.1 0.0017 17.8 0.1 2.0 1 1 0 1 1 1 1 Cyclin, N-terminal domain Ank_2 PF12796.2 ETO23346.1 - 1e-24 86.6 7.5 1.5e-13 50.8 0.4 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETO23346.1 - 2.9e-22 77.2 8.5 1.1e-07 31.3 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 ETO23346.1 - 1.8e-17 63.3 3.8 2.4e-09 37.4 0.1 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO23346.1 - 2.2e-16 58.2 3.6 0.00012 21.9 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 ETO23346.1 - 4.4e-16 58.5 5.2 5.8e-06 26.3 0.1 4.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) BTV_NS2 PF04514.7 ETO23347.1 - 5.8 5.6 11.0 0.59 8.9 3.1 2.0 1 1 1 2 2 2 0 Bluetongue virus non-structural protein NS2 Band_3_cyto PF07565.8 ETO23348.1 - 1.7 8.1 5.0 0.39 10.1 0.1 1.9 1 1 1 2 2 2 0 Band 3 cytoplasmic domain Secretin_N_2 PF07655.8 ETO23348.1 - 2.7 8.4 14.4 21 5.5 0.1 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain Tau95 PF09734.4 ETO23349.1 - 5.2e-13 49.0 2.5 1.3e-12 47.6 1.8 1.8 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit VWA_3 PF13768.1 ETO23351.1 - 3.4e-13 49.5 0.0 5.9e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 ETO23351.1 - 2.1e-11 43.8 0.0 3.3e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 ETO23351.1 - 5.3e-11 42.9 0.0 9.5e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Transglut_C PF00927.17 ETO23351.1 - 0.12 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain DUF2721 PF11026.3 ETO23352.1 - 0.037 13.6 0.1 0.037 13.6 0.1 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF2721) WASH-7_mid PF14744.1 ETO23353.1 - 1.1e-111 373.0 16.9 1.7e-86 290.2 2.3 4.4 3 1 0 4 4 4 3 WASH complex subunit 7 WASH-7_N PF14745.1 ETO23353.1 - 1.4e-40 139.0 31.1 1.3e-16 59.9 0.4 4.8 4 1 1 5 5 5 4 WASH complex subunit 7, N-terminal WASH-7_C PF14746.1 ETO23354.1 - 1e-34 119.5 0.1 1.4e-34 119.1 0.1 1.2 1 0 0 1 1 1 1 WASH complex subunit 7, C-terminal C2 PF00168.25 ETO23355.1 - 3.8e-23 81.1 0.3 6.4e-23 80.4 0.2 1.4 1 0 0 1 1 1 1 C2 domain CEP76-C2 PF15627.1 ETO23355.1 - 0.06 12.8 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 CEP76 C2 domain DUF4041 PF13250.1 ETO23355.1 - 0.11 12.0 1.7 0.22 11.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) WD40 PF00400.27 ETO23357.1 - 1.8e-63 208.2 27.2 1.3e-10 40.7 0.2 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO23357.1 - 1.5e-12 46.4 13.9 0.00021 19.5 0.2 6.0 2 2 3 6 6 6 6 Nucleoporin Nup120/160 DUF3915 PF13054.1 ETO23357.1 - 0.021 14.7 2.2 0.8 9.6 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) YopX PF09643.5 ETO23357.1 - 0.035 14.0 2.2 0.22 11.4 1.6 2.4 1 1 0 1 1 1 0 YopX protein DUF2559 PF10832.3 ETO23357.1 - 0.17 11.6 0.9 34 4.3 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2559) HAD PF12710.2 ETO23357.1 - 0.98 9.5 3.7 1.1e+02 2.8 2.5 3.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase WD40 PF00400.27 ETO23358.1 - 1.2e-64 212.0 31.1 1.3e-12 47.0 0.1 7.2 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO23358.1 - 7.7e-15 54.0 6.5 6.3e-06 24.5 0.1 5.2 1 1 3 5 5 5 4 Nucleoporin Nup120/160 Phage_head_fibr PF11133.3 ETO23358.1 - 0.036 13.2 0.0 6.8 5.7 0.0 3.3 3 1 1 4 4 4 0 Head fiber protein Hira PF07569.6 ETO23358.1 - 0.049 12.8 1.4 3.8 6.6 0.0 2.9 3 1 1 4 4 4 0 TUP1-like enhancer of split USP7_C2 PF14533.1 ETO23358.1 - 0.064 12.6 0.4 13 5.1 0.1 3.8 2 2 2 4 4 4 0 Ubiquitin-specific protease C-terminal zf-TRAF PF02176.13 ETO23359.1 - 0.00016 22.0 5.0 0.00016 22.0 3.5 2.2 2 1 1 3 3 3 1 TRAF-type zinc finger Spc7 PF08317.6 ETO23361.1 - 0.0014 17.3 33.9 0.0014 17.3 23.5 7.0 1 1 7 8 8 8 2 Spc7 kinetochore protein DUF2413 PF10310.4 ETO23362.1 - 0.036 12.8 9.1 0.051 12.3 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF2201_N PF13203.1 ETO23362.1 - 0.039 13.1 2.4 0.04 13.0 1.7 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Herpes_US9 PF06072.6 ETO23362.1 - 0.49 10.2 2.3 0.9 9.4 1.6 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 RR_TM4-6 PF06459.7 ETO23362.1 - 2.7 7.7 9.8 5.8 6.7 6.9 1.4 1 1 0 1 1 1 0 Ryanodine Receptor TM 4-6 ETRAMP PF09716.5 ETO23362.1 - 5.1 7.1 6.8 12 5.9 4.7 1.8 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Corona_nucleoca PF00937.13 ETO23362.1 - 5.3 5.9 11.6 6.7 5.5 8.0 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Sfi1_C PF10638.4 ETO23363.1 - 0.016 15.6 0.6 0.044 14.2 0.4 1.7 1 0 0 1 1 1 0 Spindle body associated protein C-terminus Peptidase_M17_N PF02789.12 ETO23363.1 - 0.051 13.3 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain DUF3139 PF11337.3 ETO23363.1 - 0.16 12.2 0.1 0.16 12.2 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3139) AA_permease_2 PF13520.1 ETO23364.1 - 0.0058 15.2 3.6 0.0063 15.1 2.5 1.0 1 0 0 1 1 1 1 Amino acid permease GWT1 PF06423.7 ETO23365.1 - 5.8e-23 81.4 11.7 5.8e-23 81.4 8.1 2.5 3 1 0 3 3 3 1 GWT1 Ank_2 PF12796.2 ETO23366.1 - 2.4e-39 133.5 4.9 6e-16 58.5 0.0 4.6 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 ETO23366.1 - 2.9e-29 99.3 1.7 3.4e-06 26.5 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 ETO23366.1 - 7.7e-23 80.0 1.1 2.2e-05 24.5 0.0 6.1 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO23366.1 - 1.9e-19 69.6 1.4 9.3e-06 26.0 0.1 5.3 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO23366.1 - 9.5e-19 65.6 8.0 0.019 15.1 0.0 8.7 9 0 0 9 9 9 4 Ankyrin repeat MFS_2 PF13347.1 ETO23366.1 - 0.0081 14.6 0.0 0.012 14.0 0.0 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein ETRAMP PF09716.5 ETO23366.1 - 0.41 10.6 10.9 1.9 8.4 1.2 2.6 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF4094 PF13334.1 ETO23368.1 - 0.058 13.7 0.1 0.1 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) DUF4168 PF13767.1 ETO23370.1 - 0.056 14.0 0.1 0.076 13.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4168) DUF3037 PF11236.3 ETO23372.1 - 2.4 8.2 7.5 0.96 9.5 1.0 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) PTH2 PF01981.11 ETO23373.1 - 0.097 12.3 2.6 0.29 10.8 0.3 2.9 1 1 0 2 2 2 0 Peptidyl-tRNA hydrolase PTH2 DUF2024 PF09630.5 ETO23373.1 - 0.11 12.2 1.4 0.46 10.2 1.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) PH PF00169.24 ETO23374.1 - 1.2e-06 28.6 0.3 2.3e-06 27.7 0.0 1.5 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 ETO23374.1 - 0.064 13.5 0.3 0.12 12.6 0.2 1.6 1 1 0 1 1 1 0 Pleckstrin homology domain GTP_cyclohydroI PF01227.17 ETO23375.1 - 3.9e-65 218.4 0.6 5.3e-65 218.0 0.4 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 ETO23375.1 - 0.015 15.2 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 QueF-like protein CAP_GLY PF01302.20 ETO23376.1 - 2.6e-11 43.0 0.1 4.5e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain ATP_transf PF09830.4 ETO23376.1 - 0.08 12.7 0.2 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 ATP adenylyltransferase CLASP_N PF12348.3 ETO23378.1 - 1.3e-18 67.1 7.8 3.1e-11 43.0 2.3 3.4 2 1 0 2 2 2 2 CLASP N terminal B56 PF01603.15 ETO23379.1 - 5.6e-59 199.7 11.6 2.6e-52 177.8 3.6 2.2 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) CAP_GLY PF01302.20 ETO23379.1 - 8e-23 79.9 1.2 3.9e-21 74.5 0.1 2.6 2 0 0 2 2 2 1 CAP-Gly domain SDA1 PF05285.7 ETO23379.1 - 8 5.6 38.1 0.14 11.4 20.5 2.1 2 0 0 2 2 2 0 SDA1 Glyoxalase PF00903.20 ETO23380.1 - 1.7e-15 57.0 0.5 4.4e-15 55.7 0.1 1.9 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 ETO23380.1 - 2.2e-07 30.8 0.1 0.00014 21.8 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 ETO23380.1 - 0.00041 20.9 0.1 0.23 12.0 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 ETO23380.1 - 0.00046 20.1 0.0 0.0041 17.0 0.0 2.1 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Pox_A28 PF04584.9 ETO23380.1 - 0.0099 15.7 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 1 Poxvirus A28 family Glyoxalase_3 PF13468.1 ETO23380.1 - 0.033 14.0 0.1 0.19 11.6 0.1 2.3 1 1 0 1 1 1 0 Glyoxalase-like domain SAM_1 PF00536.25 ETO23381.1 - 6.1e-09 35.9 0.2 8.6e-09 35.4 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO23381.1 - 4.8e-08 32.7 0.1 7.1e-08 32.1 0.1 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Mito_fiss_reg PF05308.6 ETO23383.1 - 0.076 12.3 9.7 0.15 11.3 6.7 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator zf-CCHC_3 PF13917.1 ETO23383.1 - 0.72 9.6 9.0 1.1 9.0 0.1 3.4 3 1 0 3 3 3 0 Zinc knuckle LMBR1 PF04791.11 ETO23384.1 - 2.4e-11 42.8 9.4 2.4e-11 42.8 6.5 1.7 1 1 1 2 2 2 1 LMBR1-like membrane protein Exo_endo_phos PF03372.18 ETO23385.1 - 1.1e-09 38.5 0.0 1.5e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 ETO23385.1 - 0.0096 15.5 0.0 0.023 14.3 0.0 1.9 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase TFR_dimer PF04253.10 ETO23386.1 - 2e-07 30.6 0.0 3e-07 30.0 0.0 1.3 1 1 0 1 1 1 1 Transferrin receptor-like dimerisation domain DUF830 PF05708.7 ETO23386.1 - 0.069 13.1 0.0 0.19 11.6 0.0 1.7 2 0 0 2 2 2 0 Orthopoxvirus protein of unknown function (DUF830) BBP1_C PF15272.1 ETO23387.1 - 0.0013 18.2 28.0 0.0094 15.5 7.5 2.9 1 1 1 2 2 2 1 Spindle pole body component BBP1, C-terminal FadA PF09403.5 ETO23387.1 - 0.0028 17.6 5.8 0.0028 17.6 4.0 2.2 1 1 1 2 2 2 1 Adhesion protein FadA DUF342 PF03961.8 ETO23387.1 - 0.0053 15.2 8.4 0.0053 15.2 5.9 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF342) Tup_N PF08581.5 ETO23387.1 - 0.0085 16.2 26.3 0.53 10.4 0.7 3.3 3 0 0 3 3 3 3 Tup N-terminal OEP PF02321.13 ETO23387.1 - 0.029 13.9 6.4 0.15 11.6 0.2 2.3 2 0 0 2 2 2 0 Outer membrane efflux protein Pox_A_type_inc PF04508.7 ETO23387.1 - 0.03 14.0 9.8 2.3 8.2 0.0 5.0 4 1 0 4 4 4 0 Viral A-type inclusion protein repeat PilJ PF13675.1 ETO23387.1 - 0.038 14.2 6.2 0.67 10.2 4.2 2.5 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term HR1 PF02185.11 ETO23387.1 - 0.063 13.0 0.7 0.063 13.0 0.5 4.0 3 2 0 3 3 3 0 Hr1 repeat DivIC PF04977.10 ETO23387.1 - 0.12 11.8 0.1 0.12 11.8 0.1 3.9 4 0 0 4 4 4 0 Septum formation initiator Suppressor_APC PF11414.3 ETO23387.1 - 0.4 10.4 20.2 0.26 11.1 0.8 4.0 3 1 1 4 4 4 0 Adenomatous polyposis coli tumour suppressor protein F_actin_bind PF08919.5 ETO23387.1 - 0.4 10.3 0.1 0.4 10.3 0.1 3.0 1 1 1 3 3 3 0 F-actin binding NAAA-beta PF15508.1 ETO23387.1 - 0.44 10.9 2.9 3.9 7.9 0.3 2.9 1 1 2 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase YlqD PF11068.3 ETO23387.1 - 0.51 10.3 28.0 0.059 13.4 9.7 2.7 1 1 2 3 3 3 0 YlqD protein CorA PF01544.13 ETO23387.1 - 0.7 8.8 9.2 0.15 11.0 2.0 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Filament PF00038.16 ETO23387.1 - 0.79 9.1 25.7 21 4.4 17.8 2.7 1 1 0 1 1 1 0 Intermediate filament protein Ead_Ea22 PF13935.1 ETO23387.1 - 1.1 9.5 12.4 17 5.7 8.6 2.2 1 1 0 1 1 1 0 Ead/Ea22-like protein ZapA PF05164.8 ETO23387.1 - 1.2 9.1 9.7 0.1 12.5 1.7 2.6 2 1 1 3 3 3 0 Cell division protein ZapA WXG100 PF06013.7 ETO23387.1 - 1.5 8.9 9.9 1.5 8.9 1.1 3.2 3 0 0 3 3 3 0 Proteins of 100 residues with WXG V-SNARE PF05008.10 ETO23387.1 - 2 8.6 17.5 0.72 10.0 0.6 4.1 3 1 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF228 PF02989.9 ETO23387.1 - 2.2 7.8 5.0 1.3 8.5 1.3 2.2 1 1 1 2 2 2 0 Lyme disease proteins of unknown function Kinetocho_Slk19 PF12709.2 ETO23387.1 - 3 7.9 20.5 1 9.4 0.7 3.9 4 0 0 4 4 4 0 Central kinetochore-associated Mnd1 PF03962.10 ETO23387.1 - 3.3 7.3 24.7 0.24 11.0 6.5 2.4 1 1 2 3 3 3 0 Mnd1 family Cob_adeno_trans PF01923.13 ETO23387.1 - 6 6.6 11.7 1.7 8.4 2.2 2.3 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Caps_synth_GfcC PF06251.6 ETO23387.1 - 6.7 5.7 12.5 1.1 8.3 0.4 3.0 2 1 1 3 3 3 0 Capsule biosynthesis GfcC Baculo_p24 PF05073.7 ETO23387.1 - 7.1 6.1 12.3 61 3.1 8.6 2.1 1 1 0 1 1 1 0 Baculovirus P24 capsid protein DUF3373 PF11853.3 ETO23387.1 - 8.3 4.8 15.4 2.3 6.6 2.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3373) Ion_trans PF00520.26 ETO23388.1 - 1.8e-26 92.6 38.5 1.1e-19 70.4 18.2 2.5 2 0 0 2 2 2 2 Ion transport protein WD40 PF00400.27 ETO23390.1 - 4e-54 178.6 19.6 2.6e-10 39.7 0.5 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO23390.1 - 9.3e-14 50.4 1.6 4.4e-06 25.1 0.0 4.6 1 1 3 5 5 5 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO23390.1 - 0.0087 15.5 0.5 0.5 9.7 0.0 2.8 2 1 0 2 2 2 1 PQQ-like domain DUF4221 PF13970.1 ETO23390.1 - 0.11 11.8 7.6 0.21 10.8 0.3 3.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4221) eIF-3c_N PF05470.7 ETO23391.1 - 0.26 9.3 14.8 0.34 8.9 10.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PITH PF06201.8 ETO23392.1 - 1.3e-18 67.1 0.1 1.9e-18 66.7 0.1 1.2 1 0 0 1 1 1 1 PITH domain Peptidase_C97 PF05903.9 ETO23392.1 - 0.0051 16.5 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 PPPDE putative peptidase domain DcuC PF03606.10 ETO23393.1 - 0.13 10.4 0.4 0.16 10.2 0.3 1.1 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier PT PF04886.7 ETO23395.1 - 8.1e-13 47.4 142.8 0.017 14.4 9.3 7.1 1 1 2 3 3 3 2 PT repeat FHIPEP PF00771.15 ETO23397.1 - 0.017 13.4 1.3 0.02 13.2 0.9 1.0 1 0 0 1 1 1 0 FHIPEP family Mem_trans PF03547.13 ETO23397.1 - 0.021 13.1 2.2 0.025 12.8 1.5 1.2 1 0 0 1 1 1 0 Membrane transport protein CDC45 PF02724.9 ETO23397.1 - 0.046 11.7 9.2 0.053 11.5 6.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.17 ETO23397.1 - 0.06 12.3 5.1 0.075 12.0 3.5 1.3 1 1 0 1 1 1 0 ZIP Zinc transporter Apt1 PF10351.4 ETO23397.1 - 0.33 9.7 16.0 0.28 10.0 10.4 1.3 1 1 0 1 1 1 0 Golgi-body localisation protein domain OATP PF03137.15 ETO23397.1 - 4.2 5.2 9.2 5 5.0 5.7 1.6 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Cnd1_N PF12922.2 ETO23397.1 - 7.7 6.1 13.6 17 5.0 9.1 1.8 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term SID-1_RNA_chan PF13965.1 ETO23397.1 - 8.6 4.3 7.6 6.1 4.8 4.5 1.4 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4611 PF15387.1 ETO23398.1 - 0.22 11.6 2.1 0.45 10.6 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) BK_channel_a PF03493.13 ETO23399.1 - 0.019 14.8 0.1 0.037 13.9 0.1 1.5 1 0 0 1 1 1 0 Calcium-activated BK potassium channel alpha subunit DEAD PF00270.24 ETO23400.1 - 5.4e-31 107.3 0.0 5.4e-29 100.8 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 ETO23400.1 - 7.9e-27 92.9 0.0 2.9e-26 91.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.1 ETO23400.1 - 0.046 12.7 0.0 0.081 11.9 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Kelch_3 PF13415.1 ETO23401.1 - 1.3e-24 85.6 4.7 1.8e-11 43.8 0.1 3.5 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO23401.1 - 2.1e-20 72.2 3.9 4.6e-11 42.3 0.4 4.0 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO23401.1 - 6.3e-15 54.6 3.4 3.5e-07 30.1 0.3 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 ETO23401.1 - 3.1e-11 42.9 8.5 3.6e-10 39.5 0.1 3.4 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 ETO23401.1 - 9.6e-11 41.0 1.4 0.0011 18.6 0.2 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO23401.1 - 1.9e-09 36.9 4.3 0.00012 21.5 0.1 3.3 3 0 0 3 3 3 2 Kelch motif TPK_catalytic PF04263.11 ETO23401.1 - 0.064 12.8 0.0 0.48 10.0 0.0 2.3 2 0 0 2 2 2 0 Thiamin pyrophosphokinase, catalytic domain DUF1980 PF09323.5 ETO23401.1 - 1 9.0 8.4 0.28 10.9 3.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) GH97_C PF14509.1 ETO23401.1 - 1.8 8.7 6.3 6 7.0 0.0 2.9 3 0 0 3 3 3 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation LST1 PF05083.8 ETO23402.1 - 0.13 12.2 0.5 4.2 7.4 0.4 2.5 2 0 0 2 2 2 0 LST-1 protein MIP-T3 PF10243.4 ETO23402.1 - 2.1 6.7 66.3 2.7 6.3 45.9 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SOBP PF15279.1 ETO23402.1 - 8.3 6.6 22.3 11 6.2 15.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein EF-hand_5 PF13202.1 ETO23403.1 - 3.6e-06 26.0 1.8 1.4e-05 24.1 1.2 2.1 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 ETO23403.1 - 4.1e-06 26.8 1.2 9.8e-05 22.4 0.0 3.0 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO23403.1 - 5e-06 25.4 0.6 5e-06 25.4 0.4 2.2 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 ETO23403.1 - 0.00035 20.1 1.0 0.0008 18.9 0.2 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO23403.1 - 0.00055 19.6 0.4 0.0021 17.7 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.2 ETO23403.1 - 0.059 13.1 0.5 0.12 12.1 0.3 1.6 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand HNF-1_N PF04814.8 ETO23404.1 - 0.064 13.3 2.7 0.065 13.3 0.1 1.9 1 1 1 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Vac_Fusion PF02346.11 ETO23404.1 - 0.85 9.0 4.4 1.5 8.2 1.8 2.3 2 0 0 2 2 2 0 Chordopoxvirus fusion protein DUF908 PF06012.7 ETO23406.1 - 0.078 12.2 2.1 0.12 11.6 1.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) PRKCSH PF07915.8 ETO23406.1 - 0.61 10.9 5.0 2 9.2 3.5 1.9 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein DUSP PF06337.7 ETO23407.1 - 1.9e-16 60.2 1.1 8.3e-15 55.0 0.7 2.4 2 0 0 2 2 2 1 DUSP domain GPCR_chapero_1 PF11904.3 ETO23408.1 - 0.011 14.8 0.1 0.011 14.8 0.1 1.1 1 0 0 1 1 1 0 GPCR-chaperone Alg14 PF08660.6 ETO23408.1 - 0.016 15.1 1.9 0.019 14.9 1.3 1.2 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like Anoctamin PF04547.7 ETO23408.1 - 0.017 13.7 3.5 0.017 13.7 2.4 1.0 1 0 0 1 1 1 0 Calcium-activated chloride channel DUF2207 PF09972.4 ETO23408.1 - 0.081 11.4 1.2 0.089 11.3 0.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3796 PF12676.2 ETO23408.1 - 0.5 10.5 5.4 0.6 10.3 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) DUF3810 PF12725.2 ETO23408.1 - 2.4 6.9 7.1 1.8 7.4 4.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) peroxidase PF00141.18 ETO23409.1 - 1.3e-40 139.3 0.0 1.6e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 Peroxidase Myosin_HC-like PF07058.6 ETO23409.1 - 0.068 12.2 0.0 0.091 11.8 0.0 1.1 1 0 0 1 1 1 0 Myosin II heavy chain-like G-alpha PF00503.15 ETO23410.1 - 1.5e-19 69.9 0.3 1.5e-19 69.9 0.2 3.0 2 1 1 3 3 3 2 G-protein alpha subunit Arf PF00025.16 ETO23410.1 - 0.00081 18.6 0.3 0.0019 17.4 0.2 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF3045 PF11243.3 ETO23410.1 - 0.037 14.2 0.1 0.086 13.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3045) Ebola_NP PF05505.7 ETO23410.1 - 0.11 10.5 7.1 0.13 10.3 4.9 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Xol-1_GHMP-like PF09109.5 ETO23410.1 - 0.13 12.3 4.1 0.17 11.9 2.3 1.5 1 1 0 1 1 1 0 Switch protein XOL-1, GHMP-like Secretin_N_2 PF07655.8 ETO23410.1 - 0.51 10.7 6.3 0.34 11.3 2.6 1.9 2 0 0 2 2 2 0 Secretin N-terminal domain PBP1_TM PF14812.1 ETO23410.1 - 4.3 7.7 9.4 5.2 7.4 3.0 2.8 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tropomyosin_1 PF12718.2 ETO23411.1 - 4.2e-06 26.6 20.6 7.6e-05 22.5 8.3 2.1 1 1 1 2 2 2 2 Tropomyosin like ADIP PF11559.3 ETO23411.1 - 0.00014 21.8 20.0 0.0029 17.5 7.6 2.1 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding HOOK PF05622.7 ETO23411.1 - 0.00016 19.6 11.1 0.00016 19.6 7.7 2.0 1 1 1 2 2 2 1 HOOK protein bZIP_1 PF00170.16 ETO23411.1 - 0.0015 18.4 22.2 0.028 14.3 2.2 3.3 3 1 1 4 4 3 2 bZIP transcription factor ATG16 PF08614.6 ETO23411.1 - 0.002 18.0 22.6 0.057 13.2 8.7 2.1 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) DUF3450 PF11932.3 ETO23411.1 - 0.006 15.8 10.9 0.051 12.8 3.4 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) IncA PF04156.9 ETO23411.1 - 0.0099 15.4 19.0 0.1 12.1 13.2 2.1 1 1 0 1 1 1 1 IncA protein Filament PF00038.16 ETO23411.1 - 0.012 15.0 19.9 0.091 12.2 2.7 2.2 1 1 1 2 2 2 0 Intermediate filament protein Myosin_tail_1 PF01576.14 ETO23411.1 - 0.018 12.7 22.8 0.093 10.4 15.8 1.8 1 1 0 1 1 1 0 Myosin tail TPR_MLP1_2 PF07926.7 ETO23411.1 - 0.023 14.4 16.1 0.052 13.2 11.2 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 ETO23411.1 - 0.027 14.2 25.7 0.027 14.2 5.4 2.8 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Microtub_assoc PF07989.6 ETO23411.1 - 0.03 14.1 1.3 0.03 14.1 0.9 3.3 2 1 1 3 3 3 0 Microtubule associated TBPIP PF07106.8 ETO23411.1 - 0.036 13.6 15.9 0.057 12.9 5.0 2.4 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tropomyosin PF00261.15 ETO23411.1 - 0.04 13.0 20.7 0.072 12.1 7.9 2.7 1 1 1 2 2 2 0 Tropomyosin TMF_TATA_bd PF12325.3 ETO23411.1 - 0.044 13.5 17.6 0.062 13.0 7.7 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.6 ETO23411.1 - 0.056 12.0 20.1 0.031 12.9 7.1 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein GAS PF13851.1 ETO23411.1 - 0.064 12.4 20.1 0.025 13.8 10.3 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Shugoshin_N PF07558.6 ETO23411.1 - 0.07 12.8 5.1 0.69 9.6 0.2 2.8 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF972 PF06156.8 ETO23411.1 - 0.083 13.2 15.5 0.47 10.8 0.6 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF972) PEARLI-4 PF05278.7 ETO23411.1 - 0.098 12.0 15.4 0.19 11.0 2.9 2.0 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) bZIP_2 PF07716.10 ETO23411.1 - 0.12 12.2 0.8 0.12 12.2 0.5 4.1 4 2 1 5 5 3 0 Basic region leucine zipper DUF2205 PF10224.4 ETO23411.1 - 0.12 11.9 13.6 2.1 7.9 4.6 2.6 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) Reo_sigmaC PF04582.7 ETO23411.1 - 0.12 11.4 3.5 0.21 10.7 2.5 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Cauli_AT PF03233.8 ETO23411.1 - 0.13 11.9 11.6 1.1 8.9 1.7 2.3 1 1 1 2 2 2 0 Aphid transmission protein Phlebovirus_NSM PF07246.6 ETO23411.1 - 0.14 11.2 16.6 0.025 13.7 6.1 2.0 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M Lebercilin PF15619.1 ETO23411.1 - 0.16 11.4 22.1 0.065 12.6 8.6 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Prefoldin PF02996.12 ETO23411.1 - 0.18 11.4 13.1 0.47 10.1 0.9 3.1 2 1 1 3 3 3 0 Prefoldin subunit SlyX PF04102.7 ETO23411.1 - 0.19 12.1 16.0 0.36 11.2 2.4 3.8 1 1 3 4 4 3 0 SlyX BLOC1_2 PF10046.4 ETO23411.1 - 0.27 11.3 11.2 0.088 12.9 4.3 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ERM PF00769.14 ETO23411.1 - 0.29 10.6 20.0 0.57 9.6 8.3 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family COG5 PF10392.4 ETO23411.1 - 0.31 11.0 11.1 2.9 7.8 4.0 2.2 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DUF904 PF06005.7 ETO23411.1 - 0.43 10.9 22.8 6.7 7.0 9.1 3.7 1 1 1 2 2 2 0 Protein of unknown function (DUF904) SPAM PF02090.10 ETO23411.1 - 0.44 10.5 10.8 1 9.3 5.6 2.2 1 1 1 2 2 2 0 Salmonella surface presentation of antigen gene type M protein DUF1515 PF07439.6 ETO23411.1 - 0.46 10.3 10.9 0.77 9.5 1.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Nup54 PF13874.1 ETO23411.1 - 0.56 9.8 14.2 0.69 9.5 6.1 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 CCDC155 PF14662.1 ETO23411.1 - 0.56 9.7 18.4 0.27 10.8 3.7 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 NPV_P10 PF05531.7 ETO23411.1 - 0.57 10.4 7.5 3.1 8.1 1.3 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.17 ETO23411.1 - 0.62 10.1 18.2 0.2 11.6 5.4 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Atg14 PF10186.4 ETO23411.1 - 0.66 8.8 22.7 0.42 9.5 6.6 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Jnk-SapK_ap_N PF09744.4 ETO23411.1 - 0.68 9.9 17.1 0.94 9.4 7.4 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF3972 PF13118.1 ETO23411.1 - 0.69 9.9 10.2 0.21 11.6 1.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3972) AAA_13 PF13166.1 ETO23411.1 - 0.79 8.1 14.8 1.4 7.2 10.3 1.5 1 1 0 1 1 1 0 AAA domain DUF4200 PF13863.1 ETO23411.1 - 0.9 9.4 20.0 0.69 9.8 6.4 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Syntaxin-6_N PF09177.6 ETO23411.1 - 0.94 9.9 12.3 0.22 11.9 3.1 2.8 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DUF2730 PF10805.3 ETO23411.1 - 0.96 9.2 9.4 0.92 9.2 2.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) KLRAQ PF10205.4 ETO23411.1 - 0.96 9.5 17.2 0.15 12.1 5.1 2.8 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein DUF2203 PF09969.4 ETO23411.1 - 0.97 9.6 6.7 0.8 9.9 2.5 2.2 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF4140 PF13600.1 ETO23411.1 - 0.99 9.8 12.0 1.9 8.9 1.4 2.9 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) Fib_alpha PF08702.5 ETO23411.1 - 1.3 9.1 14.9 0.37 10.8 5.6 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Macoilin PF09726.4 ETO23411.1 - 1.3 7.1 18.2 3.1 5.9 12.6 1.6 1 1 0 1 1 1 0 Transmembrane protein DUF444 PF04285.7 ETO23411.1 - 1.3 7.5 11.2 3.5 6.1 7.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF444) DUF948 PF06103.6 ETO23411.1 - 1.5 8.7 6.9 5.4 6.9 0.3 3.0 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF3552 PF12072.3 ETO23411.1 - 1.6 7.8 24.0 0.07 12.3 6.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) LOH1CR12 PF10158.4 ETO23411.1 - 1.7 8.4 6.0 3.4 7.4 1.2 2.4 1 1 1 2 2 2 0 Tumour suppressor protein Prefoldin_2 PF01920.15 ETO23411.1 - 2 8.2 23.7 0.58 9.9 1.0 3.5 2 1 2 4 4 3 0 Prefoldin subunit Ax_dynein_light PF10211.4 ETO23411.1 - 2.1 8.1 19.5 0.51 10.1 7.5 3.0 1 1 2 3 3 3 0 Axonemal dynein light chain TSC22 PF01166.13 ETO23411.1 - 2.3 8.2 10.2 5.7 6.9 0.6 3.5 1 1 2 3 3 3 0 TSC-22/dip/bun family FlxA PF14282.1 ETO23411.1 - 2.7 7.9 20.8 0.59 10.1 7.0 3.2 1 1 0 2 2 2 0 FlxA-like protein DivIC PF04977.10 ETO23411.1 - 2.9 7.4 22.8 0.35 10.3 0.6 3.7 2 1 2 4 4 4 0 Septum formation initiator Spc24 PF08286.6 ETO23411.1 - 3 7.5 20.1 0.51 10.0 2.3 3.6 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 DUF724 PF05266.9 ETO23411.1 - 3.1 7.3 19.9 1.9 8.0 7.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) MbeD_MobD PF04899.7 ETO23411.1 - 3.2 7.7 8.3 8.6 6.3 0.5 2.9 2 1 0 3 3 2 0 MbeD/MobD like RTBV_P46 PF06216.6 ETO23411.1 - 3.3 6.4 6.3 7.4 5.2 0.8 2.1 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein V_ATPase_I PF01496.14 ETO23411.1 - 4 5.1 15.7 0.14 9.9 3.7 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 ETO23411.1 - 4.8 6.1 18.3 6.4 5.7 3.0 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Uds1 PF15456.1 ETO23411.1 - 4.8 7.2 18.1 9.9 6.1 5.7 2.5 1 1 1 2 2 2 0 Up-regulated During Septation DivIVA PF05103.8 ETO23411.1 - 4.9 7.2 16.1 2.6 8.1 2.2 3.0 1 1 2 3 3 3 0 DivIVA protein DUF641 PF04859.7 ETO23411.1 - 7.3 6.3 13.9 1.5 8.6 1.1 2.7 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) FlaC_arch PF05377.6 ETO23411.1 - 7.4 6.5 14.1 16 5.4 0.2 3.7 1 1 3 4 4 4 0 Flagella accessory protein C (FlaC) DUF2968 PF11180.3 ETO23411.1 - 7.7 5.8 14.9 4.6 6.5 4.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) EMP24_GP25L PF01105.19 ETO23411.1 - 8.6 6.0 10.5 1.4 8.5 2.7 2.2 1 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Iron_permease PF04120.7 ETO23411.1 - 8.9 5.8 8.7 1.5 8.3 2.1 2.4 1 1 2 3 3 3 0 Low affinity iron permease DUF4446 PF14584.1 ETO23411.1 - 10 5.9 12.8 0.83 9.4 2.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) WWE PF02825.15 ETO23413.1 - 0.24 10.8 2.2 2 7.9 1.5 2.2 1 1 0 1 1 1 0 WWE domain Sec62 PF03839.11 ETO23413.1 - 0.3 10.4 5.1 0.45 9.8 3.5 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 EF-hand_7 PF13499.1 ETO23414.1 - 1.2e-16 60.6 4.4 4e-13 49.2 2.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair Pkinase PF00069.20 ETO23414.1 - 2.3e-15 56.4 0.0 4.5e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.27 ETO23414.1 - 4e-14 50.7 11.5 1.4e-08 33.4 0.5 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 ETO23414.1 - 1.8e-12 46.0 10.7 0.00018 21.0 0.3 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 ETO23414.1 - 2.6e-11 42.3 13.5 5.6e-06 25.4 0.7 3.4 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 ETO23414.1 - 3.4e-09 36.1 8.9 8.3e-08 31.7 0.9 3.7 2 2 2 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 ETO23414.1 - 1.6e-06 28.1 2.4 5.6e-05 23.1 0.1 2.2 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 ETO23414.1 - 3.6e-05 23.4 3.3 0.00021 20.9 0.3 2.4 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Pkinase_Tyr PF07714.12 ETO23414.1 - 0.00052 19.1 0.0 0.00094 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Dockerin_1 PF00404.13 ETO23414.1 - 1.1 9.1 8.0 1.6 8.5 0.0 3.1 3 0 0 3 3 3 0 Dockerin type I repeat RasGEF_N PF00618.15 ETO23415.1 - 8.5e-06 25.8 0.1 3.4e-05 23.8 0.1 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif Polysacc_deac_1 PF01522.16 ETO23416.1 - 0.0038 16.8 0.2 0.0048 16.5 0.2 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase HCR PF07111.7 ETO23416.1 - 0.029 12.3 2.4 0.031 12.3 1.6 1.2 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) SAP30_Sin3_bdg PF13867.1 ETO23416.1 - 0.033 14.0 0.3 0.097 12.5 0.2 1.9 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Kinesin-related PF06548.6 ETO23416.1 - 0.066 11.7 9.7 0.087 11.3 6.7 1.2 1 0 0 1 1 1 0 Kinesin-related Hex_IIIa PF02455.11 ETO23416.1 - 1.3 7.6 7.4 1.5 7.3 5.2 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Mt_ATP-synt_B PF05405.9 ETO23416.1 - 1.6 8.1 5.8 0.25 10.7 0.9 1.8 1 1 1 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Filo_glycop PF01611.11 ETO23416.1 - 1.7 7.3 5.5 1.9 7.2 3.8 1.0 1 0 0 1 1 1 0 Filovirus glycoprotein HSA PF07529.8 ETO23416.1 - 4.4 7.1 11.5 0.091 12.5 0.5 2.5 2 1 0 2 2 2 0 HSA IDO PF01231.13 ETO23417.1 - 0.0011 17.5 0.6 0.0014 17.1 0.4 1.3 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase GAS PF13851.1 ETO23417.1 - 0.0018 17.5 14.5 0.0029 16.8 10.0 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Cep57_CLD_2 PF14197.1 ETO23417.1 - 0.0019 18.1 11.0 0.12 12.3 0.8 2.6 2 0 0 2 2 2 2 Centrosome localisation domain of PPC89 CCDC155 PF14662.1 ETO23417.1 - 0.0051 16.4 14.1 0.0078 15.8 9.8 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 DUF972 PF06156.8 ETO23417.1 - 0.013 15.8 4.0 0.013 15.8 2.8 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF972) bZIP_1 PF00170.16 ETO23417.1 - 0.042 13.8 2.7 0.042 13.8 1.8 2.8 2 1 0 2 2 2 0 bZIP transcription factor DUF342 PF03961.8 ETO23417.1 - 0.044 12.2 5.3 0.06 11.7 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF904 PF06005.7 ETO23417.1 - 0.053 13.8 14.1 0.86 9.9 1.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Nup54 PF13874.1 ETO23417.1 - 0.064 12.9 7.8 1.4 8.5 0.6 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 NCD2 PF04905.8 ETO23417.1 - 0.065 13.0 1.5 0.11 12.2 1.1 1.4 1 0 0 1 1 1 0 NAB conserved region 2 (NCD2) Occludin_ELL PF07303.8 ETO23417.1 - 0.075 13.7 9.6 0.11 13.2 6.1 1.7 1 1 0 1 1 1 0 Occludin homology domain IncA PF04156.9 ETO23417.1 - 0.075 12.6 14.9 0.11 12.1 10.3 1.3 1 0 0 1 1 1 0 IncA protein PilJ PF13675.1 ETO23417.1 - 0.077 13.3 1.5 0.64 10.3 0.1 2.3 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Z1 PF10593.4 ETO23417.1 - 0.14 11.3 6.0 0.15 11.2 3.6 1.5 1 1 0 1 1 1 0 Z1 domain CobT PF06213.7 ETO23417.1 - 0.18 10.8 17.5 0.28 10.2 12.1 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CENP-F_leu_zip PF10473.4 ETO23417.1 - 0.18 11.6 20.4 0.3 10.9 12.7 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mito_morph_reg PF14972.1 ETO23417.1 - 0.32 10.3 1.4 3.3 7.1 0.3 2.1 2 0 0 2 2 2 0 Mitochondrial morphogenesis regulator DivIC PF04977.10 ETO23417.1 - 0.59 9.6 7.7 2.8 7.4 1.7 2.4 1 1 1 2 2 2 0 Septum formation initiator UPF0449 PF15136.1 ETO23417.1 - 0.86 9.8 9.1 0.54 10.4 0.9 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 APG6 PF04111.7 ETO23417.1 - 2.3 7.1 16.3 6.1 5.7 11.3 1.6 1 1 0 1 1 1 0 Autophagy protein Apg6 NOA36 PF06524.7 ETO23417.1 - 3.9 6.6 19.4 6.8 5.8 13.4 1.5 1 0 0 1 1 1 0 NOA36 protein BRE1 PF08647.6 ETO23417.1 - 7.3 6.6 14.1 4.6 7.2 4.7 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase HALZ PF02183.13 ETO23417.1 - 8.4 6.2 12.9 1.1 9.0 2.5 3.2 2 1 0 2 2 2 0 Homeobox associated leucine zipper CENP-T PF15511.1 ETO23418.1 - 0.052 12.7 20.2 0.065 12.4 14.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Daxx PF03344.10 ETO23418.1 - 5 5.4 47.0 8 4.8 32.5 1.3 1 0 0 1 1 1 0 Daxx Family IPT PF01745.11 ETO23419.1 - 0.058 12.5 0.1 0.081 12.0 0.0 1.2 1 0 0 1 1 1 0 Isopentenyl transferase DUF3836 PF12930.2 ETO23420.1 - 0.039 13.4 4.8 0.043 13.3 3.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF3836) 7TM_GPCR_Srz PF10325.4 ETO23420.1 - 0.057 12.5 0.1 0.057 12.5 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srz 7TM_GPCR_Srv PF10323.4 ETO23420.1 - 0.12 11.4 0.8 0.23 10.5 0.5 1.5 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv Utp14 PF04615.8 ETO23421.1 - 0.025 12.7 6.6 0.03 12.5 4.6 1.1 1 0 0 1 1 1 0 Utp14 protein HNF-1_N PF04814.8 ETO23421.1 - 0.066 13.3 4.1 0.09 12.8 2.9 1.3 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Cwf_Cwc_15 PF04889.7 ETO23421.1 - 7.2 6.2 17.6 0.33 10.6 7.7 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein zf-DNL PF05180.7 ETO23422.1 - 0.05 13.3 0.2 0.15 11.8 0.1 1.7 1 0 0 1 1 1 0 DNL zinc finger AAA_16 PF13191.1 ETO23424.1 - 0.021 14.8 3.9 0.03 14.2 1.8 1.8 1 1 1 2 2 2 0 AAA ATPase domain Pyrophosphatase PF00719.14 ETO23426.1 - 6.2e-31 106.9 0.2 2.7e-28 98.3 0.2 2.1 1 1 0 1 1 1 1 Inorganic pyrophosphatase mRNA_cap_C PF03919.10 ETO23426.1 - 0.16 12.3 1.5 3.8 7.8 0.6 2.8 3 0 0 3 3 3 0 mRNA capping enzyme, C-terminal domain Rer1 PF03248.8 ETO23428.1 - 0.048 13.2 0.5 0.091 12.3 0.0 1.8 2 0 0 2 2 2 0 Rer1 family Tom37_C PF11801.3 ETO23428.1 - 0.083 12.7 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain CCDC66 PF15236.1 ETO23429.1 - 3 7.4 22.2 0.33 10.5 9.9 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 66 Tetraspannin PF00335.15 ETO23430.1 - 0.02 14.1 0.7 0.03 13.5 0.5 1.2 1 0 0 1 1 1 0 Tetraspanin family Neur_chan_memb PF02932.11 ETO23430.1 - 0.33 10.8 2.0 1 9.2 0.1 2.0 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Pkinase PF00069.20 ETO23431.1 - 2.6e-34 118.5 0.1 4.1e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO23431.1 - 1.6e-13 50.3 0.0 2.6e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO23431.1 - 0.00057 19.0 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO23431.1 - 0.0098 15.6 0.0 0.019 14.6 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 ETO23431.1 - 0.014 15.0 0.0 0.053 13.0 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase EF-hand_1 PF00036.27 ETO23432.1 - 2e-28 95.4 10.1 1e-07 30.7 0.5 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 ETO23432.1 - 6.5e-27 93.4 6.8 5e-13 48.9 0.8 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 ETO23432.1 - 1.2e-24 85.7 10.5 1.3e-09 37.5 0.2 4.3 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 ETO23432.1 - 2.2e-24 83.6 10.1 1e-06 27.8 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 ETO23432.1 - 2.2e-23 79.9 7.3 2.1e-05 24.0 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_9 PF14658.1 ETO23432.1 - 8.1e-10 38.4 0.2 1.9e-06 27.6 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 ETO23432.1 - 1.6e-07 31.3 2.6 0.0057 16.6 0.2 3.1 1 1 2 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 ETO23432.1 - 4.1e-06 26.4 6.3 0.074 12.7 0.1 3.2 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand TerB PF05099.8 ETO23432.1 - 8.9e-06 25.4 3.5 0.00086 19.0 0.3 3.0 2 1 1 3 3 3 1 Tellurite resistance protein TerB EF-hand_10 PF14788.1 ETO23432.1 - 9.5e-06 25.1 6.8 0.0058 16.2 0.5 3.2 2 1 1 3 3 3 2 EF hand Pkinase PF00069.20 ETO23432.1 - 1.3e-05 24.4 0.1 3.7e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain MecA_N PF05223.6 ETO23432.1 - 0.0081 16.2 0.5 0.021 14.8 0.1 1.8 2 0 0 2 2 2 1 NTF2-like N-terminal transpeptidase domain DUF3647 PF12363.3 ETO23432.1 - 0.13 12.4 3.8 3.8 7.6 0.0 2.5 1 1 1 2 2 2 0 Phage protein Arm PF00514.18 ETO23433.1 - 0.00046 19.9 0.1 0.23 11.3 0.0 2.5 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 ETO23433.1 - 0.0019 16.5 0.4 0.0029 15.9 0.3 1.2 1 0 0 1 1 1 1 Adaptin N terminal region 7TM_GPCR_Sra PF02117.11 ETO23435.1 - 0.01 14.4 1.4 0.016 13.8 1.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sra AT_hook PF02178.14 ETO23435.1 - 1.6 8.6 8.2 4.9 7.1 5.7 1.9 1 0 0 1 1 1 0 AT hook motif NfeD PF01957.13 ETO23436.1 - 0.014 15.5 0.5 0.014 15.5 0.4 2.6 1 1 2 3 3 3 0 NfeD-like C-terminal, partner-binding DUF2839 PF10999.3 ETO23436.1 - 0.5 10.4 3.4 0.71 9.9 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) Ras PF00071.17 ETO23437.1 - 6.5e-08 32.1 0.1 9.4e-08 31.6 0.1 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO23437.1 - 4.1e-05 24.0 0.0 5.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arch_ATPase PF01637.13 ETO23437.1 - 0.075 12.7 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase G-alpha PF00503.15 ETO23437.1 - 0.085 11.5 0.7 0.2 10.3 0.0 1.7 1 1 1 2 2 2 0 G-protein alpha subunit AAA_28 PF13521.1 ETO23437.1 - 0.12 12.2 0.1 0.26 11.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETO23437.1 - 0.15 12.0 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain WD40 PF00400.27 ETO23438.1 - 2.4e-54 179.3 11.9 3.9e-10 39.2 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO23438.1 - 2.1e-09 36.0 1.8 0.00048 18.3 0.2 4.6 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Rep_fac-A_3 PF08661.6 ETO23438.1 - 0.042 13.7 0.1 0.25 11.2 0.0 2.3 2 0 0 2 2 2 0 Replication factor A protein 3 WD40 PF00400.27 ETO23439.1 - 1.9e-48 160.6 21.9 1.8e-12 46.6 1.8 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO23439.1 - 7.7e-06 24.3 6.5 0.078 11.0 0.0 4.9 2 1 2 5 5 5 3 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO23439.1 - 0.00088 19.0 2.1 0.038 13.6 0.1 3.1 1 1 4 5 5 5 2 Eukaryotic translation initiation factor eIF2A Mucin PF01456.12 ETO23440.1 - 0.19 11.5 2.4 0.23 11.2 1.7 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein NPR3 PF03666.8 ETO23440.1 - 3.1 6.2 6.4 4 5.8 4.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CTP_transf_2 PF01467.21 ETO23441.1 - 3.3e-14 53.2 0.0 1.7e-13 50.9 0.0 2.1 1 1 0 1 1 1 1 Cytidylyltransferase YbaJ PF10757.4 ETO23441.1 - 0.066 13.3 0.1 0.18 11.9 0.1 1.7 1 1 0 1 1 1 0 Biofilm formation regulator YbaJ WD40 PF00400.27 ETO23442.1 - 1.8e-76 249.5 24.9 7.2e-13 47.8 0.2 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO23442.1 - 1.1e-11 43.6 8.5 0.047 11.8 0.0 5.1 1 1 3 5 5 5 5 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO23442.1 - 4.5e-06 26.5 0.0 3.2 7.7 0.0 5.7 3 2 3 6 6 6 1 Domain of unknown function (DUF3601) Cytochrom_D1 PF02239.11 ETO23442.1 - 3.5e-05 22.2 0.9 1.1 7.4 0.0 3.7 1 1 4 5 5 5 4 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO23442.1 - 3.8e-05 22.9 0.8 0.25 10.4 0.0 3.7 1 1 3 4 4 4 2 Neuroblastoma-amplified sequence, N terminal DUF1258 PF06869.7 ETO23442.1 - 8.7e-05 21.7 1.6 0.29 10.1 0.0 4.2 2 2 3 5 5 5 1 Protein of unknown function (DUF1258) Coatomer_WDAD PF04053.9 ETO23442.1 - 0.00011 21.1 0.1 0.13 11.0 0.0 2.6 1 1 1 2 2 2 2 Coatomer WD associated region PD40 PF07676.7 ETO23442.1 - 0.034 13.8 11.1 1.4 8.6 0.1 5.2 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO23442.1 - 0.039 14.2 0.9 74 3.7 0.0 4.1 3 1 1 4 4 4 0 Resistin NYD-SP28_assoc PF14775.1 ETO23442.1 - 0.064 12.9 3.8 1.2e+02 2.5 0.1 5.2 6 0 0 6 6 6 0 Sperm tail C-terminal domain SoxZ PF08770.6 ETO23442.1 - 0.091 12.2 0.0 31 4.0 0.0 3.1 3 0 0 3 3 3 0 Sulphur oxidation protein SoxZ Proteasome_A_N PF10584.4 ETO23442.1 - 0.12 11.7 7.2 37 3.7 0.0 5.4 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature 7tm_3 PF00003.17 ETO23444.1 - 1.5e-21 76.8 32.8 2.6e-21 76.0 18.8 2.9 2 1 1 3 3 3 2 7 transmembrane sweet-taste receptor of 3 GCPR Beta_helix PF13229.1 ETO23444.1 - 2.2e-11 43.7 93.5 1.5e-05 24.8 17.7 6.7 1 1 6 7 7 7 6 Right handed beta helix region XK-related PF09815.4 ETO23448.1 - 0.0004 19.4 7.4 0.00061 18.8 5.1 1.4 1 1 0 1 1 1 1 XK-related protein PsbW PF07123.7 ETO23449.1 - 1.1 9.3 5.5 0.58 10.2 1.8 2.0 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) PALP PF00291.20 ETO23453.1 - 2.4e-50 171.4 0.0 3.2e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 ETO23453.1 - 1.1e-07 31.5 1.2 0.004 16.9 0.1 3.6 2 1 0 2 2 2 2 CBS domain DUF2082 PF09855.4 ETO23453.1 - 0.014 15.2 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) RabGAP-TBC PF00566.13 ETO23454.1 - 3.7e-28 98.4 23.7 1e-27 97.0 14.0 3.1 1 1 0 2 2 2 1 Rab-GTPase-TBC domain Vfa1 PF08432.5 ETO23454.1 - 0.0015 18.5 6.6 0.0034 17.4 4.6 1.6 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Pex14_N PF04695.8 ETO23454.1 - 0.033 14.2 2.6 2.4 8.2 0.2 3.0 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CAP_N PF01213.14 ETO23454.1 - 1.8 7.7 6.8 3.7 6.7 4.7 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 ETO23454.1 - 7.2 5.8 9.1 21 4.3 6.0 2.0 1 1 0 1 1 1 0 Mitochondrial fission regulator EF-hand_1 PF00036.27 ETO23455.1 - 4.6e-10 38.0 1.7 4.7e-06 25.5 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 ETO23455.1 - 5.9e-09 35.0 0.4 5e-05 22.8 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 ETO23455.1 - 1e-08 35.1 1.9 3.9e-08 33.3 1.3 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 ETO23455.1 - 1.1e-06 27.6 1.9 4.1e-06 25.8 0.2 2.5 2 1 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 ETO23455.1 - 3.6e-06 26.4 0.3 0.00053 19.5 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair Skp1 PF01466.14 ETO23456.1 - 2.9e-33 113.7 1.1 5.8e-33 112.7 0.3 1.9 1 1 1 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 ETO23456.1 - 8.7e-10 38.5 0.1 0.00013 21.9 0.0 2.4 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain BTB PF00651.26 ETO23456.1 - 0.034 14.1 0.8 0.38 10.7 0.1 2.4 1 1 0 2 2 2 0 BTB/POZ domain Cid2 PF09774.4 ETO23456.1 - 0.2 11.7 4.1 0.31 11.1 0.7 2.3 1 1 1 2 2 2 0 Caffeine-induced death protein 2 BBS1 PF14779.1 ETO23457.1 - 2.9e-16 59.2 1.9 4.3e-16 58.6 0.1 2.1 2 1 0 3 3 3 1 Ciliary BBSome complex subunit 1 DUF2874 PF11396.3 ETO23459.1 - 0.039 13.9 0.6 0.11 12.4 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2874) HEAT_2 PF13646.1 ETO23460.1 - 0.00012 22.3 0.1 0.00027 21.1 0.1 1.6 2 0 0 2 2 2 1 HEAT repeats Pes-10 PF07149.6 ETO23460.1 - 0.00087 18.1 2.2 0.36 9.5 0.1 2.1 1 1 1 2 2 2 2 Pes-10 Cohesin_HEAT PF12765.2 ETO23460.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion PXA PF02194.10 ETO23460.1 - 0.036 13.6 4.6 1.4 8.4 3.2 2.8 1 1 0 1 1 1 0 PXA domain HEAT PF02985.17 ETO23460.1 - 0.039 14.0 0.1 0.27 11.4 0.0 2.4 2 0 0 2 2 2 0 HEAT repeat UvrD_C_2 PF13538.1 ETO23460.1 - 0.11 12.6 0.2 0.56 10.3 0.0 2.1 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain RasGEF_N PF00618.15 ETO23460.1 - 0.42 10.7 3.6 14 5.8 2.5 2.9 1 1 0 1 1 1 0 RasGEF N-terminal motif BLOC1_2 PF10046.4 ETO23462.1 - 0.0011 19.1 10.6 0.0015 18.6 4.5 2.2 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 V_ATPase_I PF01496.14 ETO23462.1 - 0.034 12.0 11.4 0.039 11.8 7.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family STAT_alpha PF01017.15 ETO23462.1 - 0.039 13.6 12.1 0.55 9.9 5.4 2.1 2 0 0 2 2 2 0 STAT protein, all-alpha domain XFP PF03894.10 ETO23462.1 - 0.047 13.2 0.7 0.067 12.7 0.4 1.3 1 1 0 1 1 1 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Reo_sigmaC PF04582.7 ETO23462.1 - 0.2 10.8 0.9 0.24 10.5 0.6 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Abi_C PF14355.1 ETO23462.1 - 0.28 11.1 2.5 5.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Abortive infection C-terminus Lebercilin PF15619.1 ETO23462.1 - 0.28 10.5 24.4 0.072 12.5 12.1 2.0 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF2115 PF09888.4 ETO23462.1 - 0.61 10.1 8.9 0.78 9.8 6.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) Nup54 PF13874.1 ETO23462.1 - 0.66 9.6 15.2 0.075 12.7 1.6 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF3450 PF11932.3 ETO23462.1 - 0.83 8.8 11.5 2.4 7.3 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) GAS PF13851.1 ETO23462.1 - 0.86 8.7 23.2 0.12 11.5 12.4 1.8 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding IPK PF03770.11 ETO23462.1 - 1.2 8.7 10.7 1.6 8.3 7.4 1.1 1 0 0 1 1 1 0 Inositol polyphosphate kinase Orbi_VP5 PF00901.12 ETO23462.1 - 1.4 7.0 9.2 1.6 6.8 6.4 1.0 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 MalF_P2 PF14785.1 ETO23462.1 - 1.5 8.6 7.2 1.2 8.9 3.4 1.9 1 1 1 2 2 2 0 Maltose transport system permease protein MalF P2 domain FliD_N PF02465.13 ETO23462.1 - 2.2 8.7 15.7 4.5 7.6 5.8 2.2 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus IncA PF04156.9 ETO23462.1 - 2.3 7.7 10.9 5.9 6.4 7.6 1.6 1 1 0 1 1 1 0 IncA protein MitMem_reg PF13012.1 ETO23462.1 - 2.5 8.2 11.1 2.2 8.4 5.0 2.1 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function DUF4407 PF14362.1 ETO23462.1 - 3.9 6.3 7.7 5.1 5.9 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.6 ETO23462.1 - 4.9 5.7 18.5 3 6.4 11.0 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein CCDC-167 PF15188.1 ETO23462.1 - 4.9 7.1 10.7 7.6 6.5 4.9 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Sec20 PF03908.8 ETO23462.1 - 5.3 6.8 9.6 1.1 8.9 3.7 1.9 2 0 0 2 2 2 0 Sec20 DASH_Dad3 PF08656.5 ETO23462.1 - 7.8 6.2 12.3 3.7 7.3 2.6 2.7 1 1 2 3 3 3 0 DASH complex subunit Dad3 NPV_P10 PF05531.7 ETO23462.1 - 8.2 6.7 6.9 7.5 6.8 2.2 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF972 PF06156.8 ETO23462.1 - 8.9 6.7 14.9 4.7 7.6 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) HSP70 PF00012.15 ETO23463.1 - 0.00022 19.3 0.7 0.00028 18.9 0.5 1.3 1 0 0 1 1 1 1 Hsp70 protein CorA PF01544.13 ETO23464.1 - 8.2e-38 130.0 0.1 1.4e-37 129.3 0.1 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein eIF-3c_N PF05470.7 ETO23464.1 - 0.13 10.3 5.2 0.19 9.7 3.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Tom22 PF04281.8 ETO23464.1 - 0.51 9.8 6.1 1.3 8.5 4.2 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Vfa1 PF08432.5 ETO23464.1 - 4.7 7.1 13.5 0.28 11.2 5.4 1.8 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DNA_pol_phi PF04931.8 ETO23464.1 - 6 4.5 11.9 10 3.7 8.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi Voldacs PF03517.8 ETO23464.1 - 7.4 6.4 11.5 1.8e+02 1.9 8.0 2.3 1 1 0 1 1 1 0 Regulator of volume decrease after cellular swelling DUF1491 PF07372.7 ETO23468.1 - 0.02 14.7 0.1 0.031 14.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1491) Actin PF00022.14 ETO23469.1 - 3.4e-82 275.9 0.0 4e-82 275.7 0.0 1.0 1 0 0 1 1 1 1 Actin DUF2975 PF11188.3 ETO23470.1 - 9.8 5.9 9.6 1.8 8.2 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) G6PD_C PF02781.11 ETO23471.1 - 1.8e-93 312.5 0.0 2.7e-93 312.0 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 ETO23471.1 - 2.3e-29 102.9 0.6 3.6e-29 102.2 0.4 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain E2_bind PF08825.5 ETO23471.1 - 0.0043 16.7 0.3 0.027 14.2 0.4 2.1 2 0 0 2 2 2 1 E2 binding domain DUF4460 PF14687.1 ETO23471.1 - 0.064 13.0 1.3 2.8 7.7 0.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4460) MFS_1 PF07690.11 ETO23472.1 - 2.4e-15 56.1 39.7 1.2e-09 37.3 14.0 3.4 2 2 1 3 3 3 3 Major Facilitator Superfamily Nuc_H_symport PF03825.11 ETO23472.1 - 3.8e-07 29.2 10.4 3.8e-07 29.2 7.2 2.1 2 0 0 2 2 2 1 Nucleoside H+ symporter MFS_2 PF13347.1 ETO23472.1 - 0.00045 18.7 9.4 0.00045 18.7 6.5 3.2 2 1 1 3 3 3 2 MFS/sugar transport protein Neur_chan_memb PF02932.11 ETO23472.1 - 0.00053 19.9 0.0 0.0015 18.5 0.0 1.7 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Adeno_E3B PF03376.9 ETO23472.1 - 0.11 12.4 2.1 0.44 10.4 0.1 2.9 2 0 0 2 2 2 0 Adenovirus E3B protein WD40 PF00400.27 ETO23473.1 - 1.2e-31 107.4 10.2 2.6e-08 33.4 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO23473.1 - 4.6e-08 31.6 0.4 0.017 13.2 0.0 3.2 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Ole-e-6 PF09253.5 ETO23473.1 - 0.0056 16.3 0.5 0.0094 15.5 0.3 1.3 1 0 0 1 1 1 1 Pollen allergen ole e 6 Nucleoporin_N PF08801.6 ETO23473.1 - 0.059 12.1 3.7 5.6 5.6 0.1 3.0 2 1 0 2 2 2 0 Nup133 N terminal like His_kinase PF06580.8 ETO23475.1 - 0.058 13.3 0.3 9.2 6.2 0.2 2.7 2 1 0 2 2 2 0 Histidine kinase DUF2951 PF11166.3 ETO23475.1 - 0.31 10.8 3.0 0.69 9.7 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2951) TFIIA PF03153.8 ETO23476.1 - 0.0011 19.0 31.3 0.16 11.8 18.3 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit CRAL_TRIO PF00650.15 ETO23476.1 - 0.012 15.1 3.7 2.8 7.3 0.0 3.2 3 0 0 3 3 3 0 CRAL/TRIO domain Pex14_N PF04695.8 ETO23476.1 - 0.046 13.7 0.1 0.046 13.7 0.0 4.2 3 1 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SapB_2 PF03489.12 ETO23476.1 - 0.45 10.5 1.6 0.54 10.3 0.1 1.9 2 0 0 2 2 2 0 Saposin-like type B, region 2 HAD PF12710.2 ETO23477.1 - 2.6e-11 44.0 0.0 4.1e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETO23477.1 - 8.5e-11 41.6 4.0 3.1e-10 39.8 2.0 2.4 2 1 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 ETO23477.1 - 2.8e-10 40.9 0.0 0.00069 20.0 0.0 2.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 ETO23477.1 - 0.0009 18.8 6.6 0.0011 18.6 0.5 3.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Herpes_UL87 PF03043.9 ETO23477.1 - 0.13 10.6 1.6 0.2 10.0 1.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family BUD22 PF09073.5 ETO23477.1 - 0.13 11.3 21.5 0.26 10.3 14.9 1.5 1 0 0 1 1 1 0 BUD22 SAPS PF04499.10 ETO23477.1 - 0.85 8.1 9.4 1.3 7.5 6.5 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Trypan_PARP PF05887.6 ETO23477.1 - 1.5 8.6 4.1 3.2 7.5 2.8 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Daxx PF03344.10 ETO23477.1 - 2.5 6.4 21.1 0.29 9.5 10.9 1.8 2 0 0 2 2 2 0 Daxx Family Vfa1 PF08432.5 ETO23477.1 - 5.8 6.9 16.0 0.25 11.3 6.6 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 SDA1 PF05285.7 ETO23477.1 - 7.7 5.7 27.4 0.47 9.6 15.4 1.6 2 0 0 2 2 2 0 SDA1 PPR_3 PF13812.1 ETO23481.1 - 0.027 14.7 0.4 26 5.4 0.0 4.1 4 0 0 4 4 4 0 Pentatricopeptide repeat domain Period_C PF12114.3 ETO23482.1 - 0.077 12.5 0.6 0.12 11.9 0.4 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Aph-1 PF06105.7 ETO23485.1 - 0.078 12.2 0.1 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 Aph-1 protein Ank PF00023.25 ETO23486.1 - 2.6e-20 71.1 0.1 0.00033 20.3 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.2 ETO23486.1 - 3.9e-20 71.9 3.4 2e-14 53.6 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO23486.1 - 2.7e-19 69.1 0.2 3.7e-11 43.2 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO23486.1 - 9.4e-17 59.4 0.2 0.0044 17.1 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 ETO23486.1 - 1.6e-13 50.4 2.0 4.4e-08 33.1 0.1 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) BTV_NS2 PF04514.7 ETO23487.1 - 0.0082 15.0 6.1 0.01 14.7 4.2 1.0 1 0 0 1 1 1 1 Bluetongue virus non-structural protein NS2 Fungal_trans_2 PF11951.3 ETO23487.1 - 0.025 13.2 3.1 0.24 9.9 0.0 2.1 1 1 1 2 2 2 0 Fungal specific transcription factor domain DHHW PF14286.1 ETO23487.1 - 0.062 12.6 3.5 0.076 12.3 2.5 1.1 1 0 0 1 1 1 0 DHHW protein RSS_P20 PF11757.3 ETO23487.1 - 0.11 12.5 2.2 5.4 7.1 0.0 2.2 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like Methyltransf_11 PF08241.7 ETO23489.1 - 3.3e-08 33.9 1.4 0.0038 17.6 0.0 4.3 4 1 1 5 5 5 2 Methyltransferase domain Methyltransf_12 PF08242.7 ETO23489.1 - 4e-05 24.0 7.3 0.00074 19.9 0.0 3.9 4 0 0 4 4 4 2 Methyltransferase domain Methyltransf_31 PF13847.1 ETO23489.1 - 6.4e-05 22.5 3.4 0.0018 17.9 0.0 3.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO23489.1 - 8.5e-05 23.1 0.0 0.00031 21.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETO23489.1 - 0.00039 19.8 0.0 0.0018 17.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 ETO23489.1 - 0.00049 20.4 0.0 0.0028 17.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETO23489.1 - 0.019 14.6 0.0 0.052 13.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 ETO23489.1 - 0.097 12.3 0.0 0.097 12.3 0.0 3.2 3 1 0 3 3 3 0 Methyltransferase domain DUF2817 PF10994.3 ETO23492.1 - 5e-41 140.9 4.5 2e-28 99.4 0.0 4.1 2 1 1 3 3 3 3 Protein of unknown function (DUF2817) Ras PF00071.17 ETO23493.1 - 1.9e-12 46.8 2.6 1.5e-09 37.4 0.2 2.1 1 1 1 2 2 2 2 Ras family Capsid_NCLDV PF04451.7 ETO23493.1 - 0.11 11.4 0.1 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Large eukaryotic DNA virus major capsid protein LMBR1 PF04791.11 ETO23494.1 - 1.2 7.6 7.3 2.2 6.7 5.0 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein EIIBC-GUT_N PF03612.9 ETO23494.1 - 8.3 5.9 10.1 0.2 11.2 0.9 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Sigma70_ner PF04546.8 ETO23495.1 - 2.2 7.8 9.0 4.2 6.9 6.2 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region JAB PF01398.16 ETO23496.1 - 3.6e-26 91.1 0.2 3.6e-26 91.1 0.1 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 ETO23496.1 - 1.2e-19 70.5 3.5 2.2e-19 69.6 1.5 2.1 3 0 0 3 3 3 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 ETO23496.1 - 7.1e-05 22.3 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Secretin_N_2 PF07655.8 ETO23498.1 - 6 7.3 14.0 1.7 9.0 7.3 1.8 2 0 0 2 2 2 0 Secretin N-terminal domain ADH_N PF08240.7 ETO23500.1 - 8.8e-11 41.5 3.0 1.3e-10 40.9 2.1 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF896 PF05979.7 ETO23500.1 - 3.4 7.3 7.1 13 5.5 0.2 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) BLVR PF06375.6 ETO23500.1 - 4.1 7.2 7.6 0.22 11.3 1.6 1.6 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Vac7 PF12751.2 ETO23501.1 - 0.75 8.5 4.0 0.17 10.6 0.2 1.8 1 1 1 2 2 2 0 Vacuolar segregation subunit 7 Protocadherin PF08374.6 ETO23501.1 - 7.7 6.0 16.0 1.5 8.4 5.1 2.0 2 0 0 2 2 2 0 Protocadherin DUF3522 PF12036.3 ETO23502.1 - 3e-26 92.3 6.5 3.7e-26 92.0 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) SNARE PF05739.14 ETO23503.1 - 3.3e-07 29.8 0.9 5.2e-07 29.2 0.6 1.3 1 0 0 1 1 1 1 SNARE domain Peptidase_C97 PF05903.9 ETO23504.1 - 0.014 15.1 0.2 0.025 14.3 0.1 1.5 1 1 0 1 1 1 0 PPPDE putative peptidase domain Ribosomal_L16 PF00252.13 ETO23504.1 - 0.049 13.3 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L16p/L10e EF-hand_6 PF13405.1 ETO23505.1 - 0.014 15.2 0.1 10 6.3 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.27 ETO23505.1 - 0.031 13.5 0.0 2.1 7.8 0.0 2.5 2 0 0 2 2 2 0 EF hand Ank PF00023.25 ETO23506.1 - 3.3e-27 92.9 4.6 4.9e-08 32.4 0.0 5.1 4 1 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 ETO23506.1 - 1.9e-23 82.5 4.6 7.4e-17 61.4 0.4 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO23506.1 - 1.4e-17 63.6 5.5 0.00012 22.4 0.1 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO23506.1 - 8.9e-17 60.7 2.2 6.9e-07 29.3 0.1 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO23506.1 - 6.2e-14 50.7 3.5 0.00057 19.8 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat bZIP_1 PF00170.16 ETO23506.1 - 0.011 15.6 0.2 0.011 15.6 0.1 2.7 4 0 0 4 4 4 0 bZIP transcription factor ATG16 PF08614.6 ETO23506.1 - 0.015 15.1 4.8 0.034 13.9 3.3 1.6 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4604 PF15377.1 ETO23506.1 - 0.024 14.8 1.3 0.032 14.4 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DUF904 PF06005.7 ETO23506.1 - 0.53 10.6 11.1 0.078 13.2 4.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF972 PF06156.8 ETO23506.1 - 3.3 8.0 11.3 79 3.6 6.8 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Ank PF00023.25 ETO23507.1 - 2.8e-07 29.9 0.1 0.057 13.2 0.0 3.3 3 1 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 ETO23507.1 - 2.9e-07 30.7 0.0 3e-05 24.2 0.0 2.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO23507.1 - 4.7e-07 30.1 0.0 0.013 15.9 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO23507.1 - 2.7e-05 24.2 0.1 0.5 10.7 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO23507.1 - 0.00032 20.6 0.2 0.51 10.7 0.0 3.2 4 0 0 4 4 4 2 Ankyrin repeat Fer4_14 PF13394.1 ETO23507.1 - 0.0045 16.9 0.0 0.0067 16.4 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain RhoGEF PF00621.15 ETO23510.1 - 1.1e-43 149.2 5.5 1.5e-43 148.8 3.8 1.2 1 0 0 1 1 1 1 RhoGEF domain Ferritin PF00210.19 ETO23510.1 - 0.089 12.5 0.2 11 5.7 0.0 2.3 2 0 0 2 2 2 0 Ferritin-like domain DUF605 PF04652.11 ETO23510.1 - 2.7 7.3 13.7 4 6.7 9.5 1.2 1 0 0 1 1 1 0 Vta1 like Menin PF05053.8 ETO23510.1 - 6.4 4.8 7.1 7.9 4.5 4.9 1.1 1 0 0 1 1 1 0 Menin BTV_NS2 PF04514.7 ETO23511.1 - 0.0016 17.4 0.0 0.0016 17.4 0.0 2.1 2 1 1 3 3 3 1 Bluetongue virus non-structural protein NS2 Pex14_N PF04695.8 ETO23512.1 - 0.3 11.1 9.2 0.59 10.1 6.4 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Menin PF05053.8 ETO23512.1 - 0.76 7.8 10.9 1.1 7.3 7.6 1.2 1 0 0 1 1 1 0 Menin POX PF07526.6 ETO23512.1 - 2 8.6 11.7 0.27 11.4 5.3 1.6 2 0 0 2 2 2 0 Associated with HOX WD40 PF00400.27 ETO23513.1 - 7.9e-15 54.0 1.0 0.00016 21.3 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat FGF PF00167.13 ETO23513.1 - 0.0084 15.8 0.0 0.044 13.5 0.0 2.2 2 0 0 2 2 2 1 Fibroblast growth factor TPR_12 PF13424.1 ETO23515.1 - 4.8e-106 346.8 34.0 1.9e-14 53.3 0.2 11.0 6 3 3 11 11 11 11 Tetratricopeptide repeat TPR_10 PF13374.1 ETO23515.1 - 3.3e-75 246.0 0.0 1.3e-06 28.0 0.0 15.9 16 0 0 16 16 16 12 Tetratricopeptide repeat TPR_2 PF07719.12 ETO23515.1 - 5.9e-50 163.2 51.0 5.5e-05 22.7 0.0 16.3 16 0 0 16 16 16 12 Tetratricopeptide repeat TPR_11 PF13414.1 ETO23515.1 - 1.7e-49 165.3 41.7 6.7e-08 32.0 0.1 12.6 5 4 10 15 15 15 13 TPR repeat TPR_7 PF13176.1 ETO23515.1 - 2.2e-48 158.2 32.3 2.1e-06 27.0 0.0 15.4 15 0 0 15 15 15 11 Tetratricopeptide repeat TPR_1 PF00515.23 ETO23515.1 - 7.3e-47 155.1 54.3 6.8e-08 31.7 0.0 15.6 16 0 0 16 16 16 12 Tetratricopeptide repeat TPR_14 PF13428.1 ETO23515.1 - 3.4e-25 86.2 9.4 0.029 14.9 0.0 13.8 12 3 3 15 15 14 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO23515.1 - 4e-23 79.4 51.9 0.00091 18.8 0.0 14.8 16 0 0 16 16 15 7 Tetratricopeptide repeat TPR_17 PF13431.1 ETO23515.1 - 2.5e-12 45.9 15.1 0.12 12.5 0.0 11.1 13 0 0 13 13 12 3 Tetratricopeptide repeat PPR PF01535.15 ETO23515.1 - 3.3e-11 42.3 9.7 0.74 9.9 0.0 10.0 11 0 0 11 11 11 3 PPR repeat TPR_6 PF13174.1 ETO23515.1 - 7.1e-11 41.8 29.8 0.056 13.9 0.0 13.3 15 0 0 15 15 15 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO23515.1 - 9.1e-11 42.1 7.2 0.017 15.7 0.0 8.8 10 2 1 11 11 8 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO23515.1 - 8.7e-05 21.6 1.0 1.8 7.8 0.0 5.7 5 0 0 5 5 5 1 SHNi-TPR SAND PF01342.16 ETO23515.1 - 0.00012 21.6 7.6 13 5.5 0.0 7.6 7 1 2 9 9 8 0 SAND domain Imm42 PF15601.1 ETO23515.1 - 0.0074 15.7 0.0 0.031 13.7 0.0 2.1 1 0 0 1 1 1 1 Immunity protein 42 TPR_19 PF14559.1 ETO23515.1 - 0.0077 16.5 13.0 0.41 11.0 0.0 7.0 7 2 2 9 9 8 1 Tetratricopeptide repeat PPR_3 PF13812.1 ETO23515.1 - 0.019 15.1 1.8 61 4.2 0.0 5.1 6 0 0 6 6 4 0 Pentatricopeptide repeat domain TPR_9 PF13371.1 ETO23515.1 - 0.032 14.0 7.5 6.6 6.6 0.0 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 ETO23515.1 - 0.085 13.3 0.0 5.6 7.6 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO23515.1 - 0.36 10.7 11.2 1.5 8.7 0.0 6.1 7 0 0 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat Sel1 PF08238.7 ETO23515.1 - 2.4 8.9 7.5 6.7 7.5 0.0 5.0 6 0 0 6 6 4 0 Sel1 repeat Syntaxin_2 PF14523.1 ETO23516.1 - 0.35 10.9 4.4 1.8 8.6 3.0 2.1 1 1 0 1 1 1 0 Syntaxin-like protein Ctr PF04145.10 ETO23517.1 - 0.079 13.0 0.5 0.21 11.6 0.4 1.7 1 0 0 1 1 1 0 Ctr copper transporter family Abhydrolase_6 PF12697.2 ETO23518.1 - 1.2e-13 51.4 0.0 1.3e-13 51.3 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETO23518.1 - 3.1e-10 39.9 0.0 4.4e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETO23518.1 - 1.5e-06 28.0 0.0 1.7e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 ETO23518.1 - 0.00017 21.0 0.0 0.00023 20.6 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase PGAP1 PF07819.8 ETO23518.1 - 0.00059 19.5 0.0 0.00074 19.1 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF2305 PF10230.4 ETO23518.1 - 0.032 13.6 0.0 0.035 13.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF915 PF06028.6 ETO23518.1 - 0.034 13.2 0.0 0.062 12.3 0.0 1.4 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 ETO23518.1 - 0.04 13.3 0.0 0.043 13.2 0.0 1.1 1 0 0 1 1 1 0 Putative esterase DUF676 PF05057.9 ETO23518.1 - 0.052 12.8 0.0 0.072 12.3 0.0 1.4 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.3 ETO23518.1 - 0.078 12.8 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Thioesterase PF00975.15 ETO23518.1 - 0.1 12.7 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Methyltransf_16 PF10294.4 ETO23519.1 - 1.3e-10 40.9 0.0 1.7e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase DUF2970 PF11174.3 ETO23520.1 - 2.4 7.7 5.6 3.2 7.3 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) WD40 PF00400.27 ETO23521.1 - 1e-19 69.5 2.0 4.8e-10 38.9 0.2 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat PD40 PF07676.7 ETO23521.1 - 0.00065 19.3 0.7 0.34 10.6 0.0 3.3 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 ETO23521.1 - 0.036 13.3 0.8 39 3.6 0.0 3.9 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature BEN PF10523.4 ETO23521.1 - 0.041 13.9 0.0 0.087 12.8 0.0 1.6 1 1 0 1 1 1 0 BEN domain Nbas_N PF15492.1 ETO23521.1 - 0.081 12.0 0.0 5.1 6.1 0.0 2.2 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Kinesin PF00225.18 ETO23523.1 - 8.7e-74 248.2 7.0 4.6e-73 245.8 2.5 2.9 1 1 0 2 2 2 2 Kinesin motor domain Ni_hydr_CYTB PF01292.15 ETO23524.1 - 0.12 11.7 1.4 2.6 7.3 0.1 2.2 1 1 0 2 2 2 0 Prokaryotic cytochrome b561 RhoGAP PF00620.22 ETO23525.1 - 3.5e-05 23.4 0.2 0.00012 21.7 0.0 1.9 2 1 0 2 2 2 1 RhoGAP domain DUF4475 PF14753.1 ETO23525.1 - 0.00095 18.7 3.0 0.0014 18.1 2.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4475) Peptidase_M43 PF05572.8 ETO23525.1 - 0.026 14.1 0.6 0.038 13.5 0.4 1.2 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A DUF4288 PF14119.1 ETO23525.1 - 0.094 12.8 2.1 0.23 11.5 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4288) Phage_CI_repr PF07022.8 ETO23526.1 - 0.099 12.7 0.0 0.18 11.8 0.0 1.5 1 1 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain RhoGAP PF00620.22 ETO23527.1 - 1.4e-13 50.7 0.3 6.7e-12 45.2 0.2 2.1 1 1 0 1 1 1 1 RhoGAP domain DUF1426 PF07234.6 ETO23527.1 - 0.12 12.0 2.0 0.2 11.3 0.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1426) DENN PF02141.16 ETO23528.1 - 1.9e-25 89.6 1.1 4.4e-25 88.4 0.3 2.0 2 0 0 2 2 2 1 DENN (AEX-3) domain dDENN PF03455.14 ETO23528.1 - 2.1e-07 30.9 0.3 6.2e-07 29.3 0.2 1.8 1 0 0 1 1 1 1 dDENN domain PPR_2 PF13041.1 ETO23528.1 - 3.1e-06 27.0 0.2 5.2e-05 23.1 0.0 2.5 2 0 0 2 2 2 1 PPR repeat family PDGLE PF13190.1 ETO23528.1 - 0.11 12.2 0.3 7.4 6.3 0.2 2.5 1 1 0 1 1 1 0 PDGLE domain PPR PF01535.15 ETO23528.1 - 0.23 11.5 0.0 0.23 11.5 0.0 2.2 2 0 0 2 2 2 0 PPR repeat DUF3614 PF12267.3 ETO23529.1 - 0.0034 17.6 0.6 0.0034 17.6 0.4 2.3 1 1 0 2 2 2 1 Protein of unknown function (DUF3614) DUF4645 PF15488.1 ETO23529.1 - 0.016 14.4 5.2 0.033 13.3 3.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4645) Utp14 PF04615.8 ETO23529.1 - 1.2 7.2 43.7 1.5 6.8 30.3 1.1 1 0 0 1 1 1 0 Utp14 protein Nop14 PF04147.7 ETO23530.1 - 0.038 11.9 12.1 0.037 11.9 8.4 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 ETO23530.1 - 0.099 10.6 11.9 0.1 10.6 8.2 1.0 1 0 0 1 1 1 0 CDC45-like protein SGT1 PF07093.6 ETO23530.1 - 0.12 10.7 9.3 0.12 10.7 6.4 1.1 1 0 0 1 1 1 0 SGT1 protein BUD22 PF09073.5 ETO23530.1 - 0.52 9.3 9.3 0.6 9.1 6.4 1.2 1 0 0 1 1 1 0 BUD22 YL1 PF05764.8 ETO23530.1 - 0.54 9.8 10.6 0.62 9.6 7.4 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Daxx PF03344.10 ETO23530.1 - 0.57 8.6 14.3 0.62 8.4 9.9 1.0 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 ETO23530.1 - 1.2 8.3 12.6 1.2 8.3 8.7 1.1 1 0 0 1 1 1 0 SDA1 Sporozoite_P67 PF05642.6 ETO23530.1 - 1.7 6.4 6.0 1.6 6.4 4.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen eIF-3c_N PF05470.7 ETO23530.1 - 1.8 6.5 7.2 1.7 6.6 5.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus FAM176 PF14851.1 ETO23530.1 - 2.5 7.7 7.6 4.2 7.0 5.3 1.3 1 0 0 1 1 1 0 FAM176 family Sigma70_ner PF04546.8 ETO23530.1 - 3.3 7.2 13.2 4.3 6.8 9.2 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region RRN3 PF05327.6 ETO23530.1 - 3.8 5.5 7.2 3.9 5.4 5.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF1510 PF07423.6 ETO23530.1 - 9.6 5.5 10.6 13 5.0 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NAD_binding_5 PF07994.7 ETO23531.1 - 5.3e-53 180.4 0.0 6.4e-53 180.1 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 ETO23532.1 - 3.2e-48 162.2 0.1 6e-48 161.3 0.1 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase NAD_binding_5 PF07994.7 ETO23532.1 - 1.8e-08 34.2 0.0 2e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Claudin_2 PF13903.1 ETO23532.1 - 0.042 13.5 0.1 0.063 12.9 0.0 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF3300 PF11737.3 ETO23532.1 - 0.09 12.0 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3300) DUF912 PF06024.7 ETO23532.1 - 2.8 8.0 8.3 4 7.5 4.5 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TSP_1 PF00090.14 ETO23532.1 - 3.6 7.7 6.8 10 6.2 4.7 1.9 1 1 0 1 1 1 0 Thrombospondin type 1 domain Glyco_transf_8 PF01501.15 ETO23533.1 - 1.4e-16 60.6 0.0 3.7e-16 59.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 Pkinase PF00069.20 ETO23534.1 - 1.9e-17 63.2 4.4 1e-14 54.3 0.2 2.6 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO23534.1 - 8e-07 28.3 0.3 2.8e-06 26.6 0.1 1.8 1 1 1 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 ETO23534.1 - 0.0015 17.4 0.1 0.0025 16.6 0.1 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Apis_Csd PF11671.3 ETO23534.1 - 5.7 6.7 14.5 0.088 12.6 5.0 1.8 2 0 0 2 2 2 0 Complementary sex determiner protein DUF2956 PF11169.3 ETO23534.1 - 6.5 6.7 10.4 0.37 10.7 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) RhoGEF PF00621.15 ETO23535.1 - 2.3e-08 34.1 0.1 3.5e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain Solute_trans_a PF03619.11 ETO23536.1 - 0.0018 17.6 0.5 0.0036 16.6 0.3 1.7 1 1 0 1 1 1 1 Organic solute transporter Ostalpha PDEase_I PF00233.14 ETO23537.1 - 6e-58 196.3 0.5 7.3e-58 196.1 0.4 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Pes-10 PF07149.6 ETO23537.1 - 0.0062 15.3 0.1 0.0089 14.8 0.1 1.1 1 0 0 1 1 1 1 Pes-10 DUF1810 PF08837.6 ETO23537.1 - 0.11 12.0 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1810) SNF2_N PF00176.18 ETO23539.1 - 1e-58 198.5 4.5 1.9e-58 197.6 3.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETO23539.1 - 6.3e-16 57.9 0.1 2.7e-15 55.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.19 ETO23539.1 - 9.5e-12 44.4 5.7 2.9e-06 26.8 0.2 3.9 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.24 ETO23539.1 - 8.8e-08 31.8 0.1 4.2e-07 29.6 0.0 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase FYRN PF05964.9 ETO23540.1 - 1.5e-11 43.5 0.2 2.9e-11 42.6 0.1 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.9 ETO23540.1 - 2.5e-11 43.2 4.0 0.00015 21.5 0.0 3.3 3 0 0 3 3 3 2 F/Y rich C-terminus 2OG-FeII_Oxy PF03171.15 ETO23541.1 - 2.6e-09 37.2 0.0 6.6e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MAPEG PF01124.13 ETO23542.1 - 5e-05 22.9 0.0 0.00012 21.7 0.0 1.6 2 0 0 2 2 2 1 MAPEG family DUF4318 PF14201.1 ETO23543.1 - 0.073 12.9 0.4 0.19 11.5 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4318) DUF2684 PF10885.3 ETO23543.1 - 0.082 12.7 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2684) DUF2559 PF10832.3 ETO23543.1 - 0.36 10.6 5.2 0.2 11.4 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2559) Pkinase PF00069.20 ETO23544.1 - 7.8e-09 35.0 0.0 1.3e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO23544.1 - 1.4e-06 27.5 0.0 2.6e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase MaoC_dehydrat_N PF13452.1 ETO23544.1 - 0.065 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase Lipoprotein_6 PF01441.14 ETO23544.1 - 0.067 13.0 0.3 0.067 13.0 0.2 1.7 2 0 0 2 2 2 0 Lipoprotein Pkinase PF00069.20 ETO23545.1 - 3.3e-31 108.3 0.1 9.3e-31 106.9 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO23545.1 - 2.6e-12 46.3 0.0 3.4e-09 36.1 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.9 ETO23545.1 - 0.08 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO23545.1 - 0.086 12.5 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family VWA_2 PF13519.1 ETO23546.1 - 1.4e-06 28.4 0.0 3.4e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 ETO23546.1 - 7.6e-06 25.7 0.0 0.0062 16.2 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain DUF2201 PF09967.4 ETO23546.1 - 0.0017 18.3 0.0 0.45 10.5 0.0 2.4 2 0 0 2 2 2 2 VWA-like domain (DUF2201) vWA-TerF-like PF10138.4 ETO23546.1 - 0.0018 18.1 0.0 0.021 14.6 0.0 2.1 2 0 0 2 2 2 1 vWA found in TerF C terminus VWA_CoxE PF05762.9 ETO23546.1 - 0.018 14.2 0.0 3.5 6.7 0.0 2.2 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein RHD3 PF05879.7 ETO23547.1 - 3.2e-05 22.1 0.1 8.9e-05 20.6 0.0 1.8 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 ETO23547.1 - 5e-05 22.4 0.1 0.00015 20.9 0.0 1.8 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 ETO23547.1 - 0.0086 15.9 0.1 0.078 12.7 0.0 2.6 2 0 0 2 2 2 1 Dynamin family TPR_19 PF14559.1 ETO23548.1 - 0.00042 20.5 2.5 0.58 10.5 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO23548.1 - 0.002 17.7 0.5 12 6.0 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO23548.1 - 0.0059 16.4 4.9 0.49 10.4 0.1 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO23548.1 - 0.018 14.6 2.5 3.1 7.5 0.1 3.5 3 1 0 3 3 3 0 TPR repeat Apc3 PF12895.2 ETO23548.1 - 0.025 14.7 2.8 4.4 7.5 0.0 3.2 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 ETO23548.1 - 0.025 14.4 3.4 30 4.6 0.0 4.4 3 2 2 6 6 6 0 Tetratricopeptide repeat BDV_P24 PF06595.6 ETO23548.1 - 0.064 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Borna disease virus P24 protein TPR_14 PF13428.1 ETO23548.1 - 0.091 13.4 0.1 11 6.9 0.0 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF3753 PF12575.3 ETO23548.1 - 0.21 11.4 4.3 0.67 9.8 3.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) TPR_1 PF00515.23 ETO23548.1 - 0.73 9.5 5.3 5.9 6.6 0.1 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Endotoxin_N PF03945.9 ETO23549.1 - 0.0018 17.6 0.4 0.0043 16.4 0.2 1.7 1 1 1 2 2 2 1 delta endotoxin, N-terminal domain TPR_12 PF13424.1 ETO23549.1 - 0.05 13.5 0.2 3.9 7.4 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat OPT PF03169.10 ETO23552.1 - 0.16 10.3 5.4 0.25 9.6 3.8 1.2 1 0 0 1 1 1 0 OPT oligopeptide transporter protein RGS PF00615.14 ETO23553.1 - 0.0019 18.3 2.7 0.0037 17.3 1.8 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain WD40 PF00400.27 ETO23554.1 - 2.3e-66 217.4 20.3 2.4e-11 43.0 0.0 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO23554.1 - 1.5e-10 39.8 1.3 0.076 11.1 0.1 5.0 2 1 2 4 4 4 4 Nucleoporin Nup120/160 Kelch_5 PF13854.1 ETO23555.1 - 0.00032 20.5 0.5 1.6 8.7 0.1 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO23555.1 - 0.0017 18.4 5.0 0.37 11.0 0.0 4.1 3 1 1 4 4 4 2 Kelch motif DKNYY PF13644.1 ETO23555.1 - 0.019 15.2 1.7 0.019 15.2 1.2 2.1 1 1 1 2 2 2 0 DKNYY family GF_recep_IV PF14843.1 ETO23555.1 - 0.15 11.6 1.7 0.36 10.4 0.0 2.0 2 0 0 2 2 2 0 Growth factor receptor domain IV ADH_zinc_N PF00107.21 ETO23556.1 - 9.1e-15 54.3 0.1 1.5e-14 53.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETO23556.1 - 6e-12 45.2 0.1 9.8e-12 44.5 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain FlbD PF06289.6 ETO23556.1 - 0.12 11.7 0.1 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Flagellar protein (FlbD) IFT20 PF14931.1 ETO23557.1 - 9.6e-13 48.0 7.0 2.2e-12 46.9 4.8 1.6 1 1 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 FAM117 PF15388.1 ETO23557.1 - 0.034 13.3 0.6 0.046 12.9 0.4 1.2 1 0 0 1 1 1 0 Protein Family FAM117 DASH_Dad3 PF08656.5 ETO23557.1 - 2.1 8.0 11.6 4.5 7.0 4.1 2.4 1 1 1 2 2 2 0 DASH complex subunit Dad3 DUF848 PF05852.6 ETO23557.1 - 6.8 6.5 9.1 1.2 8.9 2.7 2.2 2 1 1 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) GAS PF13851.1 ETO23558.1 - 0.0066 15.6 16.9 0.0066 15.6 11.7 3.8 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding EF-hand_7 PF13499.1 ETO23558.1 - 0.0076 16.3 0.5 0.63 10.2 0.1 3.0 2 0 0 2 2 2 1 EF-hand domain pair ORF6C PF10552.4 ETO23558.1 - 0.01 15.5 0.7 0.01 15.5 0.5 3.2 2 1 1 3 3 3 0 ORF6C domain EF-hand_1 PF00036.27 ETO23558.1 - 0.013 14.7 5.1 1.5 8.2 0.1 3.1 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.1 ETO23558.1 - 0.017 14.7 1.7 5.5 6.6 0.3 3.1 2 1 0 2 2 2 0 EF-hand domain pair Atg14 PF10186.4 ETO23558.1 - 0.49 9.2 37.9 0.012 14.6 16.1 3.0 2 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 FUSC PF04632.7 ETO23558.1 - 2.2 6.6 5.0 3.2 6.0 3.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF904 PF06005.7 ETO23558.1 - 2.5 8.4 43.0 0.86 9.9 2.6 5.8 3 1 1 4 4 4 0 Protein of unknown function (DUF904) DUF724 PF05266.9 ETO23558.1 - 7.7 6.0 27.9 1.7 8.2 7.6 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF724) DivIC PF04977.10 ETO23558.1 - 9.8 5.7 34.8 1.5 8.3 0.8 5.8 2 1 4 6 6 6 0 Septum formation initiator EF-hand_6 PF13405.1 ETO23559.1 - 0.0013 18.4 0.1 0.0087 15.8 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 ETO23559.1 - 0.015 14.9 0.3 0.041 13.5 0.2 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_7 PF13499.1 ETO23559.1 - 0.015 15.4 0.1 0.052 13.6 0.0 1.9 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.27 ETO23559.1 - 0.08 12.2 0.3 0.43 10.0 0.0 2.2 2 0 0 2 2 2 0 EF hand Cmc1 PF08583.5 ETO23560.1 - 0.00044 19.9 6.0 0.0012 18.6 4.1 1.7 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Iso_dh PF00180.15 ETO23563.1 - 3.7e-12 45.8 0.0 4.1e-12 45.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MCR_alpha_N PF02745.10 ETO23563.1 - 0.1 11.7 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, N-terminal domain Iso_dh PF00180.15 ETO23564.1 - 6e-38 130.6 0.0 7.5e-38 130.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1107 PF06526.7 ETO23565.1 - 0.049 13.4 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1107) TPR_12 PF13424.1 ETO23566.1 - 5e-28 96.8 10.7 3.2e-18 65.4 2.5 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO23566.1 - 3.2e-17 61.3 15.4 9.4e-09 34.5 2.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO23566.1 - 1.4e-15 56.7 7.8 6.2e-08 32.1 1.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 ETO23566.1 - 8.8e-15 53.3 9.2 3.4e-07 29.6 0.8 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO23566.1 - 4.1e-14 51.1 0.8 4.6e-05 22.8 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO23566.1 - 2e-11 43.4 0.2 4.4e-05 23.2 0.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO23566.1 - 2.8e-10 39.2 14.7 4.7e-05 22.8 1.9 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat SNAP PF14938.1 ETO23566.1 - 2.4e-06 26.9 0.9 4.1e-06 26.1 0.6 1.3 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.1 ETO23566.1 - 1.4e-05 25.2 1.8 0.042 14.3 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.13 ETO23566.1 - 6.5e-05 22.7 3.0 0.064 13.1 0.2 2.5 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain TPR_16 PF13432.1 ETO23566.1 - 0.00034 21.2 0.0 0.00072 20.1 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO23566.1 - 0.00054 19.9 6.4 0.15 12.3 0.3 3.1 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO23566.1 - 0.001 19.5 0.0 0.93 10.3 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO23566.1 - 0.001 19.1 2.4 0.0033 17.5 1.4 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF627 PF04781.7 ETO23566.1 - 0.0012 18.3 1.4 0.9 9.1 0.1 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF627) SHNi-TPR PF10516.4 ETO23566.1 - 0.0064 15.7 0.2 0.082 12.1 0.0 2.6 3 0 0 3 3 3 1 SHNi-TPR TPR_19 PF14559.1 ETO23566.1 - 0.016 15.5 0.1 0.12 12.7 0.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.7 ETO23566.1 - 0.029 14.1 4.7 1.9 8.3 0.4 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Sec5 PF15469.1 ETO23566.1 - 0.32 10.7 6.8 0.13 11.9 0.2 2.9 2 1 1 3 3 3 0 Exocyst complex component Sec5 Aldedh PF00171.17 ETO23568.1 - 8.7e-56 189.1 0.2 1.7e-35 122.2 0.0 3.0 3 0 0 3 3 3 3 Aldehyde dehydrogenase family DUF1487 PF07368.6 ETO23568.1 - 0.00067 18.9 0.2 0.0017 17.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) Dala_Dala_lig_C PF07478.8 ETO23569.1 - 0.056 12.8 6.2 0.057 12.7 4.0 1.3 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus Ribosomal_L6e PF01159.14 ETO23569.1 - 1.9 8.7 7.5 2.3 8.5 5.2 1.1 1 0 0 1 1 1 0 Ribosomal protein L6e Chlam_PMP PF02415.12 ETO23572.1 - 1.2 9.4 9.6 45 4.5 0.0 4.7 4 1 0 4 4 4 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Daxx PF03344.10 ETO23572.1 - 1.4 7.3 42.5 0.17 10.3 25.6 1.8 2 0 0 2 2 2 0 Daxx Family CENP-T PF15511.1 ETO23572.1 - 2.4 7.3 29.2 0.17 11.1 15.0 2.1 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T DUF1688 PF07958.6 ETO23574.1 - 3.5e-128 427.7 0.8 4.3e-127 424.1 0.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1688) GTP_cyclohydro2 PF00925.15 ETO23574.1 - 1.4e-16 60.2 0.0 3.6e-16 58.8 0.0 1.7 2 0 0 2 2 2 1 GTP cyclohydrolase II DUF2419 PF10343.4 ETO23574.1 - 0.0013 18.0 0.0 0.0058 15.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2419) GTP_CH_N PF12471.3 ETO23574.1 - 0.005 16.4 0.0 0.0092 15.6 0.0 1.5 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal PIP5K PF01504.13 ETO23577.1 - 7.4e-22 77.6 0.2 1.4e-21 76.7 0.1 1.4 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Ras PF00071.17 ETO23578.1 - 3.1e-14 52.6 0.4 0.0001 21.7 0.0 4.1 3 1 0 3 3 3 3 Ras family Miro PF08477.8 ETO23578.1 - 4.3e-07 30.4 0.6 0.027 14.9 0.2 3.6 3 0 0 3 3 3 2 Miro-like protein Arf PF00025.16 ETO23578.1 - 2.9e-05 23.3 0.4 1.9 7.6 0.0 4.0 4 0 0 4 4 4 2 ADP-ribosylation factor family DUF3439 PF11921.3 ETO23578.1 - 0.028 14.1 11.3 0.059 13.1 7.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Zip PF02535.17 ETO23578.1 - 0.18 10.7 3.8 0.24 10.3 2.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter SSP160 PF06933.6 ETO23578.1 - 0.98 7.3 12.7 1.6 6.6 8.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.12 ETO23578.1 - 1.1 8.9 18.6 2.5 7.8 12.9 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Imm47 PF15586.1 ETO23579.1 - 0.076 12.8 1.2 0.46 10.3 0.1 2.5 2 0 0 2 2 2 0 Immunity protein 47 LKAAEAR PF15478.1 ETO23579.1 - 0.084 13.1 0.3 0.54 10.5 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function with LKAAEAR motif Voltage_CLC PF00654.15 ETO23581.1 - 3.5e-35 121.6 15.2 5.3e-30 104.6 6.4 2.1 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.23 ETO23581.1 - 3.3e-07 29.9 0.0 0.0004 20.1 0.0 2.6 2 0 0 2 2 2 2 CBS domain RRM_1 PF00076.17 ETO23582.1 - 1.5e-51 171.8 0.1 5e-21 74.1 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO23582.1 - 2.4e-37 126.7 0.0 1.2e-14 53.9 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO23582.1 - 8e-16 57.6 0.1 8e-06 25.6 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mad3_BUB1_I PF08311.7 ETO23583.1 - 0.19 11.5 2.8 0.48 10.2 1.9 1.6 1 1 0 1 1 1 0 Mad3/BUB1 homology region 1 Annexin PF00191.15 ETO23583.1 - 0.4 10.6 0.1 0.4 10.6 0.1 2.3 2 1 1 3 3 3 0 Annexin Snapin_Pallidin PF14712.1 ETO23584.1 - 0.00036 20.7 4.6 0.00055 20.1 3.2 1.3 1 0 0 1 1 1 1 Snapin/Pallidin DUF2262 PF10020.4 ETO23584.1 - 0.0055 16.9 1.6 0.0083 16.3 1.0 1.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2262) Rep_Org_C PF06926.6 ETO23584.1 - 0.021 14.8 0.5 0.034 14.2 0.3 1.3 1 0 0 1 1 1 0 Putative replisome organiser protein C-terminus CLPTM1 PF05602.7 ETO23584.1 - 0.024 13.3 0.6 0.027 13.1 0.4 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) STE PF02200.11 ETO23584.1 - 0.031 14.4 0.1 0.045 13.9 0.1 1.3 1 0 0 1 1 1 0 STE like transcription factor KLRAQ PF10205.4 ETO23584.1 - 0.032 14.2 0.7 0.041 13.9 0.5 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Pox_D2 PF04701.8 ETO23584.1 - 0.051 13.5 2.1 0.071 13.0 1.4 1.2 1 0 0 1 1 1 0 Pox virus D2 protein DUF4611 PF15387.1 ETO23584.1 - 0.094 12.8 0.2 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) KxDL PF10241.4 ETO23584.1 - 0.1 12.4 2.2 0.17 11.7 1.6 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein DUF1664 PF07889.7 ETO23584.1 - 0.18 11.6 1.5 0.25 11.1 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FliJ PF02050.11 ETO23584.1 - 0.56 10.2 5.1 1.1 9.3 3.6 1.4 1 1 0 1 1 1 0 Flagellar FliJ protein Syntaxin PF00804.20 ETO23584.1 - 0.8 9.8 6.0 0.14 12.3 1.5 1.8 2 1 0 2 2 2 0 Syntaxin HnRNPA1 PF11627.3 ETO23585.1 - 0.0058 16.7 2.0 0.0058 16.7 1.4 1.9 2 0 0 2 2 2 1 Nuclear factor hnRNPA1 DUF1669 PF07894.7 ETO23585.1 - 7.7 5.6 12.4 0.26 10.4 3.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1669) Beta-lactamase PF00144.19 ETO23586.1 - 4.5e-48 163.9 0.0 5.9e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 ETO23586.1 - 0.066 12.4 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase DUF1398 PF07166.6 ETO23589.1 - 0.11 12.3 1.8 0.23 11.3 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) MAD PF05557.8 ETO23590.1 - 0.0033 15.5 13.3 0.0033 15.5 9.2 1.9 2 0 0 2 2 2 1 Mitotic checkpoint protein Prophage_tail PF06605.6 ETO23590.1 - 0.012 14.5 0.7 0.016 14.1 0.5 1.2 1 0 0 1 1 1 0 Prophage endopeptidase tail DUF4200 PF13863.1 ETO23590.1 - 0.05 13.5 27.4 0.66 9.9 2.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF3212 PF11486.3 ETO23590.1 - 0.053 13.2 0.4 0.074 12.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3212) DivIVA PF05103.8 ETO23590.1 - 0.12 12.4 17.1 0.032 14.2 6.5 2.1 2 0 0 2 2 2 0 DivIVA protein IncA PF04156.9 ETO23590.1 - 1.2 8.7 22.0 0.16 11.5 8.3 2.1 2 0 0 2 2 2 0 IncA protein DUF3571 PF12095.3 ETO23590.1 - 1.3 9.3 5.2 7.7 6.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3571) Laminin_I PF06008.9 ETO23590.1 - 2.6 7.3 16.7 2.7 7.2 0.5 2.3 2 1 0 2 2 2 0 Laminin Domain I DUF4559 PF15112.1 ETO23590.1 - 2.9 6.9 16.0 4.5 6.3 11.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) Atg14 PF10186.4 ETO23590.1 - 8.5 5.2 19.5 26 3.6 12.5 1.9 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Rootletin PF15035.1 ETO23590.1 - 8.7 6.2 19.6 24 4.8 0.7 2.9 1 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF4263 PF14082.1 ETO23591.1 - 0.013 15.4 6.7 0.015 15.2 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4263) Filament PF00038.16 ETO23591.1 - 0.029 13.8 13.3 0.034 13.6 9.2 1.1 1 0 0 1 1 1 0 Intermediate filament protein HrpB7 PF09486.5 ETO23591.1 - 0.043 13.7 1.7 0.048 13.5 1.0 1.2 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Lipoprotein_X PF03305.8 ETO23591.1 - 0.05 12.9 3.8 0.054 12.8 2.7 1.2 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein DUF812 PF05667.6 ETO23591.1 - 0.14 10.6 12.1 0.16 10.4 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) LOH1CR12 PF10158.4 ETO23591.1 - 0.14 11.9 5.5 0.16 11.7 3.8 1.1 1 0 0 1 1 1 0 Tumour suppressor protein HAUS-augmin3 PF14932.1 ETO23591.1 - 0.37 9.9 11.5 0.4 9.8 8.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 HemX PF04375.9 ETO23591.1 - 0.39 9.2 7.8 0.39 9.2 5.4 1.1 1 0 0 1 1 1 0 HemX CENP-Q PF13094.1 ETO23591.1 - 0.42 10.6 14.5 0.59 10.1 10.1 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit LXG PF04740.7 ETO23591.1 - 0.54 10.0 11.2 1.3 8.8 7.6 1.7 1 1 0 1 1 1 0 LXG domain of WXG superfamily APG6 PF04111.7 ETO23591.1 - 0.69 8.9 16.8 0.8 8.6 11.6 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4078 PF13300.1 ETO23591.1 - 0.7 10.0 8.9 2 8.5 6.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4078) AAA_5 PF07728.9 ETO23591.1 - 0.84 9.3 3.8 3.9 7.1 0.2 2.0 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) ARD PF03079.9 ETO23591.1 - 1 9.2 9.1 1.1 9.1 6.3 1.0 1 0 0 1 1 1 0 ARD/ARD' family DUF2630 PF10944.3 ETO23591.1 - 1.2 9.3 5.0 1.2 9.3 2.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2630) TMEM192 PF14802.1 ETO23591.1 - 1.2 7.8 6.5 1.3 7.8 4.5 1.1 1 0 0 1 1 1 0 TMEM192 family KMP11 PF03037.11 ETO23591.1 - 1.3 9.7 11.5 3.2 8.4 2.8 2.1 1 1 1 2 2 2 0 Kinetoplastid membrane protein 11 Kinesin-relat_1 PF12711.2 ETO23591.1 - 1.7 9.1 15.1 0.88 10.0 2.9 2.1 1 1 1 2 2 2 0 Kinesin motor Seryl_tRNA_N PF02403.17 ETO23591.1 - 1.7 8.7 18.1 3.6 7.6 12.5 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain eIF3_N PF09440.5 ETO23591.1 - 1.9 8.6 8.3 4.5 7.4 5.8 1.7 1 1 0 1 1 1 0 eIF3 subunit 6 N terminal domain Z1 PF10593.4 ETO23591.1 - 2.1 7.5 7.6 2.2 7.4 5.3 1.0 1 0 0 1 1 1 0 Z1 domain DUF2533 PF10752.4 ETO23591.1 - 2.2 8.6 8.0 2 8.7 4.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2533) GLE1 PF07817.8 ETO23591.1 - 2.3 7.0 8.6 2.3 7.0 6.0 1.1 1 0 0 1 1 1 0 GLE1-like protein OmpH PF03938.9 ETO23591.1 - 2.3 8.1 13.5 3.3 7.6 9.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) bZIP_1 PF00170.16 ETO23591.1 - 2.5 8.1 16.3 0.95 9.4 1.8 3.0 2 1 1 3 3 3 0 bZIP transcription factor Allexi_40kDa PF05549.6 ETO23591.1 - 2.8 7.1 5.9 3 7.0 4.1 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF3450 PF11932.3 ETO23591.1 - 2.9 7.0 10.4 1.2 8.2 5.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2203 PF09969.4 ETO23591.1 - 3 8.1 6.8 4 7.6 4.7 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Nup88 PF10168.4 ETO23591.1 - 3.7 5.2 11.0 3.8 5.2 7.6 1.0 1 0 0 1 1 1 0 Nuclear pore component Macoilin PF09726.4 ETO23591.1 - 4.3 5.5 12.7 5.3 5.2 8.8 1.2 1 0 0 1 1 1 0 Transmembrane protein Mto2_bdg PF12808.2 ETO23591.1 - 4.4 7.4 15.3 0.28 11.3 2.2 3.0 2 1 1 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Fib_alpha PF08702.5 ETO23591.1 - 5.3 7.1 12.5 5.8 7.0 8.6 1.0 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family IncA PF04156.9 ETO23591.1 - 6.1 6.3 14.5 7.4 6.1 10.1 1.1 1 0 0 1 1 1 0 IncA protein Herpes_UL6 PF01763.11 ETO23591.1 - 6.2 4.8 14.4 43 2.0 10.0 1.9 1 1 0 1 1 1 0 Herpesvirus UL6 like DUF4473 PF14747.1 ETO23591.1 - 6.3 7.0 9.4 11 6.3 0.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4473) DUF948 PF06103.6 ETO23591.1 - 7.2 6.5 8.4 4.6 7.1 2.6 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4407 PF14362.1 ETO23591.1 - 7.2 5.4 8.1 10 4.9 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PhoU PF01895.14 ETO23591.1 - 7.4 7.0 10.5 2.8 8.4 3.0 2.1 1 1 1 2 2 2 0 PhoU domain RPA_interact_M PF14767.1 ETO23591.1 - 9 7.1 12.5 3.2 8.5 6.8 1.6 1 1 1 2 2 2 0 Replication protein A interacting middle TMEM220 PF15071.1 ETO23593.1 - 1.4e-05 25.4 1.2 1.4e-05 25.4 0.8 2.4 3 0 0 3 3 3 1 Transmembrane family 220, helix DUF106 PF01956.11 ETO23593.1 - 9.3 5.7 11.3 18 4.8 7.8 1.4 1 1 0 1 1 1 0 Integral membrane protein DUF106 LMF1 PF06762.9 ETO23594.1 - 0.15 10.8 2.0 0.21 10.3 1.4 1.2 1 0 0 1 1 1 0 Lipase maturation factor WWE PF02825.15 ETO23597.1 - 7.3e-07 28.5 12.7 0.00079 18.7 0.1 4.6 4 1 0 4 4 4 2 WWE domain Peptidase_S49_N PF08496.5 ETO23597.1 - 2.8 7.7 9.9 0.77 9.5 3.6 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Rpr2 PF04032.11 ETO23598.1 - 1 9.2 9.2 0.14 12.0 0.2 3.6 3 1 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain PPP4R2 PF09184.6 ETO23599.1 - 0.037 13.5 18.2 0.054 13.0 12.6 1.4 1 0 0 1 1 1 0 PPP4R2 Ycf1 PF05758.7 ETO23599.1 - 0.038 11.7 6.1 0.041 11.6 4.3 1.1 1 0 0 1 1 1 0 Ycf1 DDHD PF02862.12 ETO23599.1 - 0.14 11.8 9.3 0.2 11.4 6.4 1.3 1 0 0 1 1 1 0 DDHD domain Daxx PF03344.10 ETO23599.1 - 0.17 10.3 26.0 0.22 9.9 18.0 1.2 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 ETO23599.1 - 0.23 10.8 23.6 0.35 10.2 16.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC27 PF09507.5 ETO23599.1 - 0.29 10.2 23.3 0.35 10.0 16.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nop14 PF04147.7 ETO23599.1 - 0.52 8.1 24.9 0.61 7.9 17.3 1.1 1 0 0 1 1 1 0 Nop14-like family Astro_capsid PF03115.9 ETO23599.1 - 0.72 8.0 8.3 0.84 7.8 5.7 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Hid1 PF12722.2 ETO23599.1 - 1.4 6.4 12.4 1.4 6.5 8.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GAGA_bind PF06217.7 ETO23599.1 - 1.7 8.5 8.7 2.1 8.2 6.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family FCP1_C PF09309.5 ETO23599.1 - 2.9 7.1 22.2 4.8 6.4 15.4 1.3 1 0 0 1 1 1 0 FCP1, C-terminal NOA36 PF06524.7 ETO23599.1 - 3.5 6.7 19.6 5.5 6.1 13.6 1.3 1 0 0 1 1 1 0 NOA36 protein FLO_LFY PF01698.11 ETO23599.1 - 3.9 6.2 12.1 5.4 5.7 8.4 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Raftlin PF15250.1 ETO23599.1 - 4.3 5.7 12.5 30 2.9 7.5 2.1 2 0 0 2 2 2 0 Raftlin Presenilin PF01080.12 ETO23599.1 - 5.9 5.6 11.1 7.6 5.2 7.7 1.2 1 0 0 1 1 1 0 Presenilin Spore_coat_CotO PF14153.1 ETO23599.1 - 8.5 5.7 23.0 15 5.0 15.9 1.3 1 0 0 1 1 1 0 Spore coat protein CotO FAM60A PF15396.1 ETO23599.1 - 9.2 5.9 11.3 4 7.1 6.2 1.5 2 0 0 2 2 2 0 Protein Family FAM60A Neur_chan_memb PF02932.11 ETO23600.1 - 0.75 9.6 17.6 0.06 13.2 3.4 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CDC50 PF03381.10 ETO23602.1 - 6e-46 156.8 2.7 7.6e-46 156.5 1.9 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Gluconate_2-dh3 PF13618.1 ETO23605.1 - 0.019 15.0 0.5 0.023 14.8 0.3 1.3 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 Orbi_NS3 PF01616.11 ETO23605.1 - 0.026 13.5 1.5 0.038 12.9 1.0 1.4 1 1 0 1 1 1 0 Orbivirus NS3 CENP-F_leu_zip PF10473.4 ETO23605.1 - 0.051 13.4 21.9 0.044 13.6 9.1 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TIR-like PF10137.4 ETO23605.1 - 0.19 11.3 1.5 0.33 10.5 0.1 1.9 1 1 2 3 3 3 0 Predicted nucleotide-binding protein containing TIR-like domain PEP-utilisers_N PF05524.8 ETO23605.1 - 0.33 10.7 5.7 2 8.1 0.5 2.6 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal WXG100 PF06013.7 ETO23605.1 - 0.35 10.8 4.7 0.49 10.4 2.8 1.6 1 1 0 1 1 1 0 Proteins of 100 residues with WXG DUF1664 PF07889.7 ETO23605.1 - 0.59 9.9 8.4 0.48 10.2 4.7 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) OmpH PF03938.9 ETO23605.1 - 1.4 8.8 12.0 2.1 8.2 8.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) LPP PF04728.8 ETO23605.1 - 1.4 8.7 4.9 0.84 9.4 0.3 2.6 2 1 0 2 2 2 0 Lipoprotein leucine-zipper Reo_sigmaC PF04582.7 ETO23605.1 - 1.6 7.7 8.5 1.2 8.2 2.5 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Peptidase_S64 PF08192.6 ETO23605.1 - 3.8 5.7 11.8 4 5.6 8.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 Uds1 PF15456.1 ETO23605.1 - 4.9 7.1 14.1 1.3 8.9 6.8 1.9 1 1 1 2 2 2 0 Up-regulated During Septation Tweety PF04906.8 ETO23605.1 - 5.3 5.3 8.0 1.2 7.4 3.1 1.6 1 1 1 2 2 2 0 Tweety Tropomyosin_1 PF12718.2 ETO23605.1 - 5.5 6.8 20.6 1.8 8.4 7.3 2.6 1 1 1 2 2 2 0 Tropomyosin like DUF342 PF03961.8 ETO23605.1 - 7.5 4.8 11.4 9.1 4.5 7.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Myosin_head PF00063.16 ETO23606.1 - 6e-29 100.6 0.0 1e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) WW PF00397.21 ETO23606.1 - 5.6e-09 35.7 0.7 1.7e-08 34.1 0.5 1.8 1 0 0 1 1 1 1 WW domain Myosin_N PF02736.14 ETO23606.1 - 1.5e-05 24.5 0.3 3.3e-05 23.4 0.2 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.1 ETO23606.1 - 0.036 14.0 0.1 0.086 12.8 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 ETO23606.1 - 0.057 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 ETO23606.1 - 0.54 10.5 2.6 0.43 10.8 0.3 1.9 2 1 0 2 2 2 0 ABC transporter EF-hand_1 PF00036.27 ETO23607.1 - 2e-11 42.3 2.6 0.00016 20.7 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 ETO23607.1 - 3.3e-10 39.9 5.0 1.1e-06 28.7 2.6 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO23607.1 - 6.3e-09 34.9 0.3 0.00019 21.0 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 ETO23607.1 - 2.6e-05 23.7 5.1 0.012 15.2 1.1 2.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 ETO23607.1 - 0.0051 16.5 2.2 0.12 12.1 0.0 2.7 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.1 ETO23607.1 - 0.0056 15.9 5.1 0.09 12.1 0.1 2.9 3 0 0 3 3 3 2 EF hand tRNA_deacylase PF04414.7 ETO23607.1 - 0.05 12.7 0.0 0.067 12.3 0.0 1.3 1 0 0 1 1 1 0 D-aminoacyl-tRNA deacylase SPARC_Ca_bdg PF10591.4 ETO23607.1 - 0.051 13.6 3.4 0.14 12.1 2.4 1.9 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Guanylate_cyc PF00211.15 ETO23608.1 - 1.2e-07 31.3 0.3 1.3e-06 27.9 0.1 2.4 2 1 1 3 3 3 1 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.1 ETO23608.1 - 5.4e-06 26.5 0.0 1.2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 ETO23608.1 - 0.0074 15.1 0.1 0.013 14.3 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 ETO23608.1 - 0.01 16.0 0.0 0.16 12.0 0.0 2.5 1 1 1 2 2 2 0 AAA domain DAP3 PF10236.4 ETO23608.1 - 0.014 14.3 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 2OG-FeII_Oxy_3 PF13640.1 ETO23609.1 - 0.00054 20.4 0.0 0.00091 19.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 ETO23609.1 - 0.058 13.6 0.0 0.096 12.9 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily TPR_12 PF13424.1 ETO23610.1 - 0.00044 20.1 0.0 0.00081 19.2 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO23610.1 - 0.0025 17.4 0.0 0.0046 16.5 0.0 1.5 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 ETO23610.1 - 0.0041 16.9 0.0 0.0099 15.7 0.0 1.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO23610.1 - 0.0071 16.0 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO23610.1 - 0.0078 15.7 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF247 PF03140.10 ETO23610.1 - 0.0099 14.9 1.7 0.015 14.2 0.1 1.8 1 1 1 2 2 2 1 Plant protein of unknown function TPR_9 PF13371.1 ETO23610.1 - 0.095 12.5 0.0 0.23 11.3 0.0 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TFIIA PF03153.8 ETO23611.1 - 0.13 12.1 54.0 0.15 11.9 32.4 2.5 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MFS_1 PF07690.11 ETO23612.1 - 2.5e-12 46.2 13.0 6.7e-12 44.7 3.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MerC PF03203.9 ETO23612.1 - 1.4 9.3 6.6 3.8 7.9 4.3 1.9 1 1 1 2 2 2 0 MerC mercury resistance protein ShK PF01549.19 ETO23613.1 - 3.1e-07 30.6 5.5 9.9e-07 29.0 3.8 1.9 1 0 0 1 1 1 1 ShK domain-like Cadherin PF00028.12 ETO23614.1 - 0.0038 17.4 0.8 0.039 14.1 0.2 2.1 2 0 0 2 2 2 1 Cadherin domain Peptidase_M4_C PF02868.10 ETO23614.1 - 0.0047 16.6 0.1 0.0073 16.0 0.0 1.4 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain DUF148 PF02520.12 ETO23614.1 - 0.073 12.8 1.2 0.16 11.8 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF148 TRM PF02005.11 ETO23615.1 - 0.048 12.5 0.4 0.058 12.3 0.3 1.0 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase FAM165 PF14981.1 ETO23615.1 - 0.07 12.6 2.7 0.14 11.6 1.9 1.5 1 0 0 1 1 1 0 FAM165 family RGS PF00615.14 ETO23616.1 - 0.015 15.4 1.3 0.023 14.8 0.9 1.3 1 0 0 1 1 1 0 Regulator of G protein signaling domain WD40 PF00400.27 ETO23618.1 - 3.1e-57 188.5 21.5 1e-09 37.8 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO23618.1 - 1.6e-10 39.7 7.7 0.031 12.4 0.1 5.8 2 1 1 4 4 4 4 Nucleoporin Nup120/160 DUF851 PF05867.6 ETO23618.1 - 0.00065 19.0 0.1 0.48 9.6 0.0 2.3 1 1 0 2 2 2 2 Protein of unknown function (DUF851) Alpha-L-AF_C PF06964.7 ETO23618.1 - 0.1 12.3 0.0 0.58 9.8 0.0 2.0 2 0 0 2 2 2 0 Alpha-L-arabinofuranosidase C-terminus HAD PF12710.2 ETO23618.1 - 0.35 11.0 2.7 12 6.0 0.1 3.1 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase LRR_6 PF13516.1 ETO23619.1 - 0.047 13.7 2.0 1.4 9.2 0.1 3.7 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.2 ETO23619.1 - 0.05 13.2 0.6 0.05 13.2 0.4 2.8 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Cut8_N PF14482.1 ETO23620.1 - 0.037 14.0 0.2 0.084 12.8 0.2 1.6 1 0 0 1 1 1 0 Cut8 proteasome-binding domain WD40 PF00400.27 ETO23622.1 - 2.8e-61 201.3 21.5 1.6e-14 53.1 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO23622.1 - 1.4e-09 37.9 3.3 0.00072 19.3 0.7 3.6 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO23622.1 - 3e-05 23.5 10.7 0.13 11.9 0.1 4.6 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO23622.1 - 7.4e-05 21.0 9.6 0.22 9.5 0.1 4.1 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO23622.1 - 0.00031 19.1 0.1 0.012 13.9 0.0 2.3 1 1 0 2 2 2 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO23622.1 - 0.0015 17.3 4.5 0.13 10.9 0.4 3.5 1 1 2 3 3 3 1 Nup133 N terminal like Resistin PF06954.6 ETO23622.1 - 0.0037 17.4 0.2 6.5 7.1 0.0 2.9 2 1 1 3 3 3 2 Resistin DUF3312 PF11768.3 ETO23622.1 - 0.017 13.3 0.0 0.027 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) PQQ_2 PF13360.1 ETO23622.1 - 0.026 13.9 0.6 0.12 11.7 0.3 2.1 1 1 1 2 2 2 0 PQQ-like domain DUF1652 PF07865.6 ETO23622.1 - 0.03 13.9 0.0 0.45 10.1 0.0 2.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1652) DUF1258 PF06869.7 ETO23622.1 - 0.047 12.7 2.1 6.7 5.7 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF1258) Proteasome_A_N PF10584.4 ETO23622.1 - 0.17 11.2 16.0 14 5.1 0.1 5.9 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature RasGEF_N PF00618.15 ETO23623.1 - 0.011 15.7 0.0 0.011 15.7 0.0 2.4 2 1 0 2 2 2 0 RasGEF N-terminal motif YrbL-PhoP_reg PF10707.4 ETO23623.1 - 0.037 13.3 0.9 0.95 8.7 0.0 2.4 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL CENP-B_dimeris PF09026.5 ETO23623.1 - 0.85 9.8 15.7 0.23 11.7 8.1 2.1 1 1 1 2 2 2 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.7 ETO23623.1 - 3.5 7.2 24.2 0.046 13.4 10.4 2.4 2 1 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein AAA PF00004.24 ETO23624.1 - 3e-09 37.1 0.0 1.3e-08 35.1 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zot PF05707.7 ETO23624.1 - 0.00046 19.7 0.1 0.0014 18.1 0.0 1.8 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) Neur_chan_LBD PF02931.18 ETO23625.1 - 0.051 12.7 1.0 0.18 10.9 0.2 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel ligand binding domain zf-C2H2_7 PF15269.1 ETO23626.1 - 0.083 12.7 1.5 0.13 12.1 0.1 2.0 2 0 0 2 2 2 0 Zinc-finger Herpes_LMP1 PF05297.6 ETO23626.1 - 3.2 6.5 6.1 4.5 6.0 4.2 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Bactofilin PF04519.8 ETO23628.1 - 0.11 12.5 0.4 0.47 10.4 0.1 1.9 2 0 0 2 2 2 0 Polymer-forming cytoskeletal DUF2320 PF10082.4 ETO23628.1 - 0.13 10.9 8.1 0.21 10.2 5.6 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2320) UPF0515 PF15135.1 ETO23628.1 - 0.54 9.2 11.5 0.22 10.5 6.6 1.4 1 1 0 1 1 1 0 Uncharacterised protein UPF0515 Nop14 PF04147.7 ETO23628.1 - 2.4 5.9 22.9 2.6 5.8 15.9 1.0 1 0 0 1 1 1 0 Nop14-like family B56 PF01603.15 ETO23629.1 - 4.5e-64 216.5 17.0 8.9e-47 159.5 1.3 3.2 2 1 1 3 3 3 2 Protein phosphatase 2A regulatory B subunit (B56 family) TPR_11 PF13414.1 ETO23629.1 - 5.4e-09 35.5 11.7 2.1e-05 24.0 0.1 2.9 2 1 1 3 3 2 2 TPR repeat TPR_19 PF14559.1 ETO23629.1 - 7e-09 35.9 0.8 1.9e-08 34.5 0.5 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO23629.1 - 1.6e-07 31.8 0.4 4.8e-07 30.2 0.1 1.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO23629.1 - 1.2e-06 27.9 10.3 0.0026 17.5 0.4 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO23629.1 - 2.6e-05 24.4 0.2 0.17 12.5 0.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO23629.1 - 0.00029 20.4 0.3 1.2 9.0 0.0 3.3 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO23629.1 - 0.0011 18.4 12.2 0.015 14.8 0.9 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO23629.1 - 0.0016 18.3 5.1 0.0033 17.3 0.5 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat AHSP PF09236.5 ETO23629.1 - 0.0019 18.3 3.3 0.0049 17.0 2.3 1.7 1 0 0 1 1 1 1 Alpha-haemoglobin stabilising protein Apc3 PF12895.2 ETO23629.1 - 0.0098 16.0 7.3 0.032 14.3 5.0 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 ETO23629.1 - 0.015 15.1 0.1 0.042 13.7 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.1 ETO23629.1 - 0.14 12.4 0.1 0.14 12.4 0.1 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETO23629.1 - 0.2 11.5 10.4 1.4 8.8 0.7 4.1 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF4407 PF14362.1 ETO23629.1 - 2.7 6.8 8.2 4.3 6.1 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4628 PF15429.1 ETO23630.1 - 4.9 6.4 14.9 6.1 6.1 10.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) OmpH PF03938.9 ETO23630.1 - 5.9 6.8 19.9 9 6.2 13.8 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4569 PF15133.1 ETO23630.1 - 9.7 5.4 16.7 11 5.3 11.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) adh_short_C2 PF13561.1 ETO23632.1 - 1.8e-14 54.0 0.0 2.3e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETO23632.1 - 8.4e-09 35.2 0.0 2.7e-08 33.5 0.0 1.7 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 ETO23632.1 - 7.2e-08 32.5 0.0 1.7e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 ETO23632.1 - 8.2e-06 25.9 0.1 1.6e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 ETO23632.1 - 0.00011 22.4 0.1 0.0017 18.6 0.0 2.1 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 ETO23632.1 - 0.00087 18.0 0.0 0.0011 17.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 ETO23632.1 - 0.003 17.2 0.0 0.013 15.1 0.0 1.9 1 1 0 1 1 1 1 KR domain DapB_N PF01113.15 ETO23632.1 - 0.0049 16.7 0.2 0.013 15.4 0.0 1.8 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus DUF1776 PF08643.5 ETO23632.1 - 0.0055 15.8 0.0 0.0071 15.5 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) F420_oxidored PF03807.12 ETO23632.1 - 0.022 15.1 0.1 0.054 13.9 0.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_3 PF03447.11 ETO23632.1 - 0.024 15.0 0.0 0.094 13.1 0.0 1.9 2 1 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 ETO23632.1 - 0.029 13.2 0.0 0.047 12.5 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_4 PF07993.7 ETO23632.1 - 0.047 12.6 0.0 0.068 12.0 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein TrkA_N PF02254.13 ETO23632.1 - 0.059 13.3 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Saccharop_dh PF03435.13 ETO23632.1 - 0.082 11.8 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF3842 PF12953.2 ETO23632.1 - 0.51 10.4 2.7 0.98 9.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3842) Borrelia_REV PF03978.8 ETO23633.1 - 0.038 13.7 1.1 0.056 13.1 0.8 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein ECH PF00378.15 ETO23634.1 - 3.6e-73 245.7 0.3 5.7e-62 209.0 0.2 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 ETO23634.1 - 0.0038 17.0 0.1 0.27 11.0 0.0 2.3 2 0 0 2 2 2 1 Peptidase family S49 Post_transc_reg PF13797.1 ETO23634.1 - 0.09 12.3 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Post-transcriptional regulator MFS_1_like PF12832.2 ETO23634.1 - 0.096 12.4 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 MFS_1 like family tRNA_lig_CPD PF08302.6 ETO23636.1 - 0.0021 17.3 0.1 0.0097 15.1 0.0 1.9 2 0 0 2 2 2 1 Fungal tRNA ligase phosphodiesterase domain WD40 PF00400.27 ETO23637.1 - 1.4e-35 119.8 17.2 3.1e-07 30.0 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Menin PF05053.8 ETO23638.1 - 0.15 10.2 7.8 0.16 10.1 5.4 1.1 1 0 0 1 1 1 0 Menin DUF2457 PF10446.4 ETO23638.1 - 0.39 9.3 12.6 0.53 8.9 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Macoilin PF09726.4 ETO23638.1 - 2.3 6.4 13.4 2.6 6.2 9.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Utp14 PF04615.8 ETO23638.1 - 3.5 5.6 18.2 4.1 5.4 12.6 1.1 1 0 0 1 1 1 0 Utp14 protein Presenilin PF01080.12 ETO23638.1 - 4.7 5.9 5.5 5.2 5.7 3.8 1.1 1 0 0 1 1 1 0 Presenilin DUF2362 PF10154.4 ETO23638.1 - 8.9 4.8 19.4 12 4.4 13.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Zip PF02535.17 ETO23638.1 - 9.3 5.1 6.3 13 4.6 4.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter TPR_12 PF13424.1 ETO23639.1 - 8.1e-12 44.9 0.9 9.9e-05 22.1 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO23639.1 - 2e-07 30.2 1.7 2e-07 30.2 1.2 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO23639.1 - 2.9e-07 29.9 0.8 9.2e-07 28.3 0.2 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO23639.1 - 3.4e-06 26.5 5.9 2.5e-05 23.8 4.1 2.2 1 1 0 1 1 1 1 TPR repeat TPR_10 PF13374.1 ETO23639.1 - 0.00024 20.9 1.4 0.057 13.3 0.2 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO23639.1 - 0.00031 20.3 0.9 0.00031 20.3 0.6 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO23639.1 - 0.00094 18.8 0.5 0.0038 16.9 0.0 2.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO23639.1 - 0.0018 18.6 0.0 0.0081 16.5 0.0 2.1 2 1 0 2 2 2 1 Tetratricopeptide repeat RPN7 PF10602.4 ETO23639.1 - 0.0094 15.3 0.1 0.016 14.5 0.0 1.6 1 1 0 1 1 1 1 26S proteasome subunit RPN7 TPR_17 PF13431.1 ETO23639.1 - 0.016 15.3 2.7 0.032 14.4 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETO23639.1 - 0.027 15.1 0.0 0.054 14.1 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETO23639.1 - 0.051 14.2 0.0 0.16 12.6 0.0 1.8 2 0 0 2 2 1 0 Tetratricopeptide repeat Apc3 PF12895.2 ETO23639.1 - 0.065 13.3 0.7 0.18 11.9 0.5 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF2225 PF09986.4 ETO23639.1 - 0.086 12.2 3.4 3.5 7.0 2.3 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Amidase PF01425.16 ETO23640.1 - 2.7e-67 227.5 0.0 3.3e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 Amidase PH PF00169.24 ETO23641.1 - 3.8e-06 27.0 7.8 2.1e-05 24.6 5.4 2.4 1 1 0 1 1 1 1 PH domain PH_11 PF15413.1 ETO23641.1 - 0.0005 20.2 5.4 0.004 17.3 3.7 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 ETO23641.1 - 0.003 17.6 0.1 0.0078 16.2 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Vasohibin PF14822.1 ETO23641.1 - 0.027 13.5 0.1 0.058 12.4 0.0 1.5 1 1 0 1 1 1 0 Vasohibin MR_MLE_C PF13378.1 ETO23642.1 - 3.5e-23 81.6 0.0 7e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 ETO23642.1 - 4.4e-12 46.0 0.0 7.5e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 ETO23642.1 - 0.016 15.6 0.0 0.065 13.7 0.0 1.9 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Asp_Glu_race PF01177.17 ETO23643.1 - 5.4e-23 82.0 0.0 6.6e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase PTA_PTB PF01515.14 ETO23643.1 - 0.1 11.6 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase PYNP_C PF07831.8 ETO23647.1 - 0.046 13.1 0.2 0.11 12.0 0.1 1.7 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain CotJB PF12652.2 ETO23647.1 - 1.3 9.1 5.4 0.79 9.8 0.6 2.8 2 1 1 3 3 3 0 CotJB protein PhyH PF05721.8 ETO23648.1 - 1.3e-06 28.6 0.0 0.0049 16.9 0.0 2.9 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) RhoGEF PF00621.15 ETO23649.1 - 1.6e-15 57.4 6.3 1.7e-14 54.0 4.3 2.5 1 1 0 1 1 1 1 RhoGEF domain PH PF00169.24 ETO23649.1 - 0.002 18.2 1.6 0.002 18.2 1.1 3.2 2 1 0 2 2 2 1 PH domain DUF2197 PF09963.4 ETO23649.1 - 0.019 14.9 3.4 0.087 12.7 2.4 2.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) HYLS1_C PF15311.1 ETO23649.1 - 0.15 12.2 0.1 0.15 12.2 0.1 3.1 3 1 1 4 4 4 0 Hydrolethalus syndrome protein 1 C-terminus FYVE PF01363.16 ETO23650.1 - 0.0012 18.7 1.1 0.0024 17.7 0.8 1.5 1 0 0 1 1 1 1 FYVE zinc finger IncA PF04156.9 ETO23650.1 - 0.36 10.3 10.3 0.024 14.2 3.2 1.9 2 0 0 2 2 2 0 IncA protein bZIP_2 PF07716.10 ETO23650.1 - 3.4 7.5 10.5 0.061 13.1 2.2 1.9 2 0 0 2 2 2 0 Basic region leucine zipper DivIC PF04977.10 ETO23650.1 - 8.3 5.9 10.4 0.35 10.3 2.2 2.3 2 0 0 2 2 2 0 Septum formation initiator Dor1 PF04124.7 ETO23651.1 - 1.6e-48 164.9 11.1 2e-48 164.6 7.7 1.0 1 0 0 1 1 1 1 Dor1-like family CsiD PF08943.5 ETO23651.1 - 0.013 14.4 0.2 0.03 13.2 0.0 1.7 2 0 0 2 2 2 0 CsiD Sec5 PF15469.1 ETO23651.1 - 0.023 14.4 5.2 0.036 13.7 3.6 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec5 PaO PF08417.7 ETO23651.1 - 0.03 14.2 0.1 0.075 12.9 0.1 1.8 1 1 0 1 1 1 0 Pheophorbide a oxygenase DUF2450 PF10475.4 ETO23651.1 - 0.05 12.4 9.0 0.083 11.7 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Vps51 PF08700.6 ETO23651.1 - 0.12 12.2 2.5 0.19 11.5 0.8 2.0 1 1 1 2 2 2 0 Vps51/Vps67 Sec2p PF06428.6 ETO23651.1 - 1.2 9.0 8.5 0.23 11.2 0.8 3.0 1 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p CENP-H PF05837.7 ETO23651.1 - 4.9 7.3 8.0 29 4.9 0.7 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) zf-piccolo PF05715.8 ETO23652.1 - 0.00083 19.3 0.1 0.0016 18.3 0.1 1.4 1 0 0 1 1 1 1 Piccolo Zn-finger SAM_1 PF00536.25 ETO23654.1 - 0.0075 16.4 0.3 0.061 13.4 0.2 2.5 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO23654.1 - 0.031 14.1 0.4 0.099 12.5 0.1 2.1 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Rabaptin PF03528.10 ETO23654.1 - 0.29 11.0 11.4 0.39 10.6 0.1 3.3 3 0 0 3 3 3 0 Rabaptin Zip PF02535.17 ETO23655.1 - 0.13 11.2 0.0 0.13 11.2 0.0 1.9 2 1 0 2 2 2 0 ZIP Zinc transporter DUF2457 PF10446.4 ETO23655.1 - 0.14 10.8 8.3 0.2 10.3 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Apis_Csd PF11671.3 ETO23655.1 - 0.51 10.1 20.0 0.95 9.2 13.9 1.4 1 0 0 1 1 1 0 Complementary sex determiner protein Macoilin PF09726.4 ETO23655.1 - 7.7 4.6 12.4 10 4.2 8.6 1.1 1 0 0 1 1 1 0 Transmembrane protein IFT46_B_C PF12317.3 ETO23657.1 - 0.13 11.6 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal MAP65_ASE1 PF03999.7 ETO23657.1 - 2.6 6.5 11.3 2.7 6.4 7.8 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) APC_CDC26 PF10471.4 ETO23657.1 - 2.9 8.6 8.1 0.61 10.8 3.0 1.8 1 1 1 2 2 2 0 Anaphase-promoting complex APC subunit 1 Tmemb_cc2 PF10267.4 ETO23657.1 - 3.1 6.3 7.3 3.4 6.1 5.1 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein MobB PF03205.9 ETO23658.1 - 0.038 13.7 0.4 0.06 13.0 0.3 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 ETO23658.1 - 0.51 10.6 5.3 0.87 9.8 3.7 1.4 1 0 0 1 1 1 0 AAA domain GlutR_dimer PF00745.15 ETO23658.1 - 1.6 8.7 8.9 2.5 8.0 6.2 1.3 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain Cir_N PF10197.4 ETO23659.1 - 0.00023 21.0 7.4 0.00023 21.0 5.1 3.9 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF3484 PF11983.3 ETO23659.1 - 9.1 7.1 12.1 9.7 7.1 1.3 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3484) Hist_deacetyl PF00850.14 ETO23663.1 - 9.1e-80 268.2 0.1 2.7e-79 266.6 0.0 1.9 2 0 0 2 2 2 1 Histone deacetylase domain Neur_chan_memb PF02932.11 ETO23665.1 - 0.026 14.4 2.6 0.097 12.5 1.8 2.0 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Menin PF05053.8 ETO23665.1 - 0.14 10.2 11.9 0.26 9.4 8.3 1.3 1 0 0 1 1 1 0 Menin FLO_LFY PF01698.11 ETO23665.1 - 0.26 10.1 10.1 0.37 9.6 7.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF4175 PF13779.1 ETO23665.1 - 5.8 4.4 8.7 7.9 4.0 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RGS PF00615.14 ETO23666.1 - 6.2e-05 23.0 5.4 0.00021 21.3 0.5 2.8 3 0 0 3 3 3 2 Regulator of G protein signaling domain Histone PF00125.19 ETO23667.1 - 1.7e-28 98.5 0.6 3.8e-28 97.4 0.4 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 ETO23667.1 - 2.9e-05 24.1 0.0 5.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 ETO23667.1 - 0.015 15.3 0.2 0.033 14.2 0.1 1.6 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 ETO23667.1 - 0.068 12.9 0.1 0.15 11.7 0.1 1.6 1 1 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 ETO23667.1 - 0.071 12.3 0.1 0.097 11.8 0.1 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Arrestin_N PF00339.24 ETO23669.1 - 0.14 12.0 2.3 0.31 10.8 1.6 1.6 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain TCTP PF00838.12 ETO23669.1 - 1.2 9.1 8.2 0.89 9.5 3.8 1.9 2 0 0 2 2 2 0 Translationally controlled tumour protein RGS PF00615.14 ETO23671.1 - 6.9e-08 32.6 0.8 1.2e-07 31.7 0.6 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain ADK_lid PF05191.9 ETO23672.1 - 2.1e-11 43.2 0.1 2.2e-08 33.6 0.1 2.6 2 0 0 2 2 2 2 Adenylate kinase, active site lid ADK PF00406.17 ETO23672.1 - 2.9e-09 36.9 0.0 6.2e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase TFIIA PF03153.8 ETO23673.1 - 1.8 8.4 14.5 2.2 8.0 10.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C3HC4_3 PF13920.1 ETO23675.1 - 0.11 12.1 0.8 0.36 10.5 0.5 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ion_trans PF00520.26 ETO23676.1 - 3.4e-32 111.3 2.1 4.1e-32 111.0 1.4 1.1 1 0 0 1 1 1 1 Ion transport protein Pkinase PF00069.20 ETO23677.1 - 1.5e-45 155.4 2.3 2.6e-23 82.4 0.0 3.0 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO23677.1 - 1.2e-22 80.2 0.0 1.8e-13 50.1 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 ETO23677.1 - 2.8e-06 26.5 0.0 0.0033 16.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 ETO23677.1 - 1.2e-05 24.5 0.0 2.3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 ETO23677.1 - 0.098 11.9 0.0 0.098 11.9 0.0 2.9 2 1 1 3 3 3 0 PhoP regulatory network protein YrbL Vac14_Fab1_bd PF12755.2 ETO23680.1 - 3.1e-22 78.7 0.2 1.1e-21 76.9 0.0 2.0 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 ETO23680.1 - 0.0001 22.0 0.0 0.0014 18.5 0.0 2.4 2 0 0 2 2 2 1 HEAT repeat DUF2481 PF10654.4 ETO23680.1 - 0.031 13.9 2.2 0.065 12.9 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2481) DUF2454 PF10521.4 ETO23681.1 - 4.4e-07 29.1 0.8 0.0028 16.7 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2454) Cnd1 PF12717.2 ETO23681.1 - 0.00061 19.6 0.3 0.022 14.6 0.0 2.1 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 ETO23681.1 - 0.00077 19.7 0.0 1 9.7 0.0 2.2 2 0 0 2 2 2 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 ETO23681.1 - 0.00078 18.8 0.2 0.66 9.2 0.0 2.9 2 1 1 3 3 3 1 CLASP N terminal GCFC PF07842.7 ETO23681.1 - 0.0042 16.4 0.8 0.043 13.1 0.1 2.0 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein CDC45 PF02724.9 ETO23681.1 - 0.0092 14.0 6.5 0.011 13.7 4.5 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF4485 PF14846.1 ETO23681.1 - 0.067 12.9 0.3 3 7.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4485) Daxx PF03344.10 ETO23681.1 - 0.34 9.3 7.7 0.43 9.0 5.4 1.1 1 0 0 1 1 1 0 Daxx Family Phage_Gp15 PF06854.6 ETO23681.1 - 0.75 9.2 4.0 0.78 9.2 2.1 1.5 1 1 0 1 1 1 0 Bacteriophage Gp15 protein DUF2457 PF10446.4 ETO23681.1 - 7.8 5.0 21.9 11 4.6 15.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2457) Vac14_Fig4_bd PF11916.3 ETO23682.1 - 1e-27 96.4 1.0 1e-27 96.4 0.7 1.7 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Arm PF00514.18 ETO23682.1 - 0.0023 17.6 0.2 0.061 13.1 0.1 2.4 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat HEAT PF02985.17 ETO23682.1 - 0.0057 16.6 0.6 0.016 15.2 0.2 2.0 2 0 0 2 2 2 1 HEAT repeat Cnd1 PF12717.2 ETO23682.1 - 0.046 13.5 1.5 0.065 13.0 1.1 1.4 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fig4_bd PF11916.3 ETO23683.1 - 2.4e-21 75.7 0.9 4.2e-21 74.9 0.6 1.4 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding zf-CCCH PF00642.19 ETO23684.1 - 0.075 12.7 4.3 0.12 12.1 2.9 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1943 PF09172.6 ETO23685.1 - 0.02 13.7 2.0 0.023 13.5 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DUF3194 PF11419.3 ETO23685.1 - 0.48 10.6 12.9 0.76 10.0 9.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3194) Helicase_C PF00271.26 ETO23685.1 - 1.1 9.2 3.8 2.8 7.8 2.5 1.8 1 1 0 1 1 1 0 Helicase conserved C-terminal domain EF-hand_6 PF13405.1 ETO23686.1 - 0.0051 16.5 0.4 0.049 13.5 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain DUF2341 PF10102.4 ETO23686.1 - 0.02 15.0 0.6 0.042 14.0 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2341) YqzE PF14038.1 ETO23686.1 - 1.1 9.0 8.1 2.5 7.9 5.6 1.6 1 0 0 1 1 1 0 YqzE-like protein NST1 PF13945.1 ETO23686.1 - 2.4 8.1 10.7 5.4 7.0 1.0 2.2 2 0 0 2 2 2 0 Salt tolerance down-regulator BLVR PF06375.6 ETO23686.1 - 9.4 6.0 14.3 2 8.2 0.3 2.4 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) zf-CW PF07496.10 ETO23687.1 - 6.2e-14 51.4 5.9 1.4e-13 50.2 4.1 1.7 1 0 0 1 1 1 1 CW-type Zinc Finger ARID PF01388.16 ETO23687.1 - 3.6e-13 49.1 0.5 3.6e-13 49.1 0.4 2.2 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain Med15 PF09606.5 ETO23687.1 - 0.034 12.3 22.3 0.043 12.0 15.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 ETO23687.1 - 0.049 11.8 17.8 0.066 11.4 12.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.8 ETO23687.1 - 0.42 10.6 8.6 0.93 9.5 5.9 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3464 PF11947.3 ETO23687.1 - 3.8 6.9 5.5 12 5.3 3.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3464) DUF4175 PF13779.1 ETO23687.1 - 4.4 4.8 24.4 6 4.4 16.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) zf-C2H2_4 PF13894.1 ETO23688.1 - 1.4e-13 50.1 22.3 0.0001 22.3 0.6 5.1 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.21 ETO23688.1 - 2.7e-09 36.8 30.9 0.00071 19.7 0.8 5.0 5 1 0 5 5 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETO23688.1 - 7.3e-09 35.4 25.1 1.3e-05 25.2 1.5 4.6 4 1 0 4 4 3 3 Zinc-finger double domain zf-C2H2_jaz PF12171.3 ETO23688.1 - 4.4e-06 26.6 19.4 0.00074 19.5 0.3 4.6 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 ETO23688.1 - 7.5e-06 25.6 18.3 0.43 10.5 0.2 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-CHCC PF10276.4 ETO23688.1 - 0.00048 19.9 2.2 0.011 15.5 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger domain Mis12 PF05859.7 ETO23688.1 - 0.007 16.1 0.0 0.012 15.3 0.0 1.4 2 0 0 2 2 2 1 Mis12 protein PyrI_C PF02748.10 ETO23688.1 - 0.017 14.5 0.4 0.017 14.5 0.2 3.8 2 2 2 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-H2C2_5 PF13909.1 ETO23688.1 - 0.027 14.6 1.7 0.027 14.6 1.2 4.9 5 2 0 5 5 5 0 C2H2-type zinc-finger domain DUF164 PF02591.10 ETO23688.1 - 0.029 14.2 0.5 0.029 14.2 0.3 3.4 3 1 2 5 5 4 0 Putative zinc ribbon domain zf-BED PF02892.10 ETO23688.1 - 0.051 13.3 1.9 0.051 13.3 1.3 4.3 1 1 3 4 4 4 0 BED zinc finger zf-C2H2_2 PF12756.2 ETO23688.1 - 0.084 12.9 17.8 3.3 7.8 1.9 3.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 ETO23688.1 - 0.12 12.6 0.7 0.12 12.6 0.5 5.4 6 0 0 6 6 5 0 Zinc-finger of C2H2 type zf-FCS PF06467.9 ETO23688.1 - 0.23 11.1 15.4 3 7.5 1.8 3.8 2 2 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif zinc-ribbons_6 PF07191.7 ETO23688.1 - 0.74 9.6 14.4 2.7 7.8 3.4 3.0 2 2 0 2 2 2 0 zinc-ribbons EGF_CA PF07645.10 ETO23688.1 - 2.3 8.2 13.3 1.8 8.6 0.3 3.2 3 1 0 3 3 3 0 Calcium-binding EGF domain zf-RING_3 PF14369.1 ETO23688.1 - 5.3 7.1 9.6 19 5.3 0.2 3.7 4 0 0 4 4 4 0 zinc-finger C1q PF00386.16 ETO23689.1 - 0.00039 20.4 0.9 0.006 16.5 0.1 2.6 2 1 0 2 2 2 1 C1q domain zf-TRAF PF02176.13 ETO23689.1 - 0.00054 20.2 8.6 0.00054 20.2 6.0 2.8 2 2 1 3 3 3 1 TRAF-type zinc finger vATP-synt_E PF01991.13 ETO23689.1 - 0.033 13.4 0.7 0.033 13.4 0.5 1.8 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit MAAL_C PF07476.6 ETO23689.1 - 0.052 12.4 0.1 0.076 11.9 0.1 1.2 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus K_trans PF02705.11 ETO23690.1 - 0.13 10.6 4.0 0.18 10.1 2.7 1.2 1 0 0 1 1 1 0 K+ potassium transporter Neur_chan_memb PF02932.11 ETO23690.1 - 1.5 8.6 9.3 2.3 8.0 6.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM176 PF14851.1 ETO23690.1 - 2.8 7.6 9.8 4.3 7.0 0.6 2.1 1 1 1 2 2 2 0 FAM176 family Rifin_STEVOR PF02009.11 ETO23691.1 - 0.0068 16.0 1.1 0.0068 16.0 0.7 3.4 4 0 0 4 4 4 2 Rifin/stevor family Pkinase PF00069.20 ETO23692.1 - 7.5e-50 169.4 0.1 1.8e-49 168.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO23692.1 - 2.1e-24 85.9 0.0 4.2e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Myosin_TH1 PF06017.8 ETO23692.1 - 1.6e-16 60.2 6.5 3.8e-16 58.9 4.5 1.6 1 0 0 1 1 1 1 Myosin tail Pkinase_C PF00433.19 ETO23692.1 - 0.00019 21.8 3.2 0.00061 20.2 0.6 2.4 2 0 0 2 2 2 1 Protein kinase C terminal domain hSac2 PF12456.3 ETO23692.1 - 0.0003 20.1 0.1 0.0013 18.1 0.0 2.1 2 0 0 2 2 2 1 Inositol phosphatase Kinase-like PF14531.1 ETO23692.1 - 0.00059 18.8 0.0 0.0017 17.4 0.0 1.8 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETO23692.1 - 0.00069 18.7 0.0 0.0014 17.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4106 PF13388.1 ETO23692.1 - 0.026 13.5 0.4 0.026 13.5 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4106) APH PF01636.18 ETO23692.1 - 0.19 11.4 0.0 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family PH PF00169.24 ETO23693.1 - 3.7e-08 33.5 5.9 4.1e-08 33.3 1.2 3.3 2 0 0 2 2 2 1 PH domain PH_8 PF15409.1 ETO23693.1 - 7.4e-05 22.7 0.1 0.00027 20.9 0.1 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain WD40 PF00400.27 ETO23693.1 - 0.00019 21.2 0.1 0.13 12.1 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat PH_9 PF15410.1 ETO23693.1 - 0.00027 21.0 1.2 0.004 17.2 0.5 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.1 ETO23693.1 - 0.029 14.6 9.5 0.26 11.5 2.1 3.7 2 1 0 2 2 2 0 Pleckstrin homology domain PH_7 PF15408.1 ETO23693.1 - 0.076 12.9 0.0 0.7 9.7 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain BRCT PF00533.21 ETO23694.1 - 0.00036 20.6 0.0 0.099 12.8 0.0 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DUF1077 PF06417.7 ETO23695.1 - 0.14 11.5 0.2 0.14 11.5 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1077) DAGK_acc PF00609.14 ETO23696.1 - 9.2e-11 42.1 0.1 1.6e-10 41.3 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain ARID PF01388.16 ETO23697.1 - 0.00052 19.8 0.0 0.0013 18.5 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain CNPase PF05881.7 ETO23697.1 - 0.019 14.4 2.0 0.029 13.7 1.3 1.3 1 1 0 1 1 1 0 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) Peptidase_S46 PF10459.4 ETO23697.1 - 0.031 12.7 10.3 0.036 12.5 7.1 1.1 1 0 0 1 1 1 0 Peptidase S46 TEX13 PF15186.1 ETO23697.1 - 1.7 8.1 10.8 0.054 13.0 0.8 2.2 1 1 0 2 2 2 0 Testis-expressed sequence 13 protein family DUF2856 PF11043.3 ETO23697.1 - 2.8 8.1 5.6 1.4 9.0 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2856) Glutaredoxin2_C PF04399.8 ETO23697.1 - 3.1 7.3 7.0 0.35 10.4 1.0 2.0 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain IL2 PF00715.12 ETO23697.1 - 4.8 6.8 7.2 5.8 6.6 0.6 2.4 2 1 0 2 2 2 0 Interleukin 2 Corona_nucleoca PF00937.13 ETO23698.1 - 0.0098 14.8 5.6 0.011 14.6 3.9 1.2 1 0 0 1 1 1 1 Coronavirus nucleocapsid protein Na_trans_assoc PF06512.8 ETO23698.1 - 0.039 13.9 10.3 0.044 13.7 7.1 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Apt1 PF10351.4 ETO23698.1 - 1.1 8.0 10.4 1.1 8.0 7.2 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF966 PF06136.8 ETO23698.1 - 1.2 8.4 11.6 1.4 8.2 8.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF3337 PF11816.3 ETO23698.1 - 1.3 8.3 10.9 1.4 8.2 7.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) DUF1510 PF07423.6 ETO23698.1 - 1.4 8.2 16.8 1.7 7.9 11.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) eIF-3c_N PF05470.7 ETO23698.1 - 5.2 5.0 12.8 6.3 4.7 8.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Hid1 PF12722.2 ETO23698.1 - 5.5 4.5 9.4 5.9 4.4 6.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein BNIP3 PF06553.7 ETO23698.1 - 6.8 6.0 11.7 8.7 5.6 8.1 1.1 1 0 0 1 1 1 0 BNIP3 CDC45 PF02724.9 ETO23698.1 - 7.4 4.4 12.5 7.7 4.4 8.7 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2419 PF10343.4 ETO23699.1 - 2.1e-71 240.5 0.4 4.2e-71 239.5 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) Dynamitin PF04912.9 ETO23700.1 - 6.4e-06 25.2 1.4 7.3e-06 25.0 0.9 1.1 1 0 0 1 1 1 1 Dynamitin EMP24_GP25L PF01105.19 ETO23700.1 - 0.0091 15.7 0.6 0.016 14.9 0.4 1.4 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Herpes_U59 PF04529.7 ETO23701.1 - 0.01 14.7 0.7 0.012 14.4 0.5 1.2 1 0 0 1 1 1 0 Herpesvirus U59 protein ZapA PF05164.8 ETO23701.1 - 0.46 10.4 0.1 0.46 10.4 0.1 2.8 2 1 0 2 2 2 0 Cell division protein ZapA SMC_Nse1 PF07574.8 ETO23701.1 - 0.53 9.8 5.0 0.5 9.9 1.6 1.9 1 1 1 2 2 2 0 Nse1 non-SMC component of SMC5-6 complex Snf7 PF03357.16 ETO23701.1 - 0.56 9.5 9.9 0.14 11.4 2.8 2.2 2 0 0 2 2 2 0 Snf7 SNARE PF05739.14 ETO23701.1 - 0.92 9.2 5.6 15 5.3 0.1 2.8 2 0 0 2 2 2 0 SNARE domain DUF4279 PF14106.1 ETO23701.1 - 1.1 9.1 4.4 8.5 6.2 0.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4279) SlyX PF04102.7 ETO23701.1 - 1.3 9.4 11.8 1.4 9.3 1.4 3.0 3 0 0 3 3 3 0 SlyX GOLGA2L5 PF15070.1 ETO23701.1 - 1.7 7.0 13.6 0.036 12.5 1.6 2.2 1 1 0 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 DUF4200 PF13863.1 ETO23701.1 - 2.3 8.2 17.3 0.84 9.5 2.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Flu_NS2 PF00601.14 ETO23701.1 - 2.9 8.1 7.2 1.3 9.2 0.3 2.8 2 1 1 3 3 3 0 Influenza non-structural protein (NS2) TMF_DNA_bd PF12329.3 ETO23701.1 - 7.2 6.5 20.9 0.72 9.7 1.5 3.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding LMSTEN PF07988.7 ETO23701.1 - 7.4 5.9 7.6 0.94 8.8 1.7 2.1 2 0 0 2 2 2 0 LMSTEN motif DUF3860 PF12976.2 ETO23702.1 - 0.0086 15.8 0.1 0.027 14.2 0.1 1.9 1 0 0 1 1 1 1 Domain of Unknown Function with PDB structure (DUF3860) UPF0118 PF01594.11 ETO23703.1 - 0.0089 15.0 0.0 0.011 14.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF20 DUF4576 PF15144.1 ETO23703.1 - 0.031 13.9 0.0 2.2 7.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4576) Enolase_C PF00113.17 ETO23703.1 - 0.095 11.6 0.1 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Enolase, C-terminal TIM barrel domain Kelch_6 PF13964.1 ETO23704.1 - 3.1e-08 33.4 1.1 0.03 14.5 0.0 4.6 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO23704.1 - 4.2e-08 32.6 3.8 0.00066 19.1 0.3 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO23704.1 - 1.8e-06 27.6 0.4 0.47 10.2 0.1 4.3 3 1 1 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO23704.1 - 4.5e-06 26.4 5.0 0.0019 18.1 0.0 4.4 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.1 ETO23704.1 - 1.5e-05 24.9 0.3 0.029 14.5 0.0 4.1 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO23704.1 - 1.5e-05 24.5 3.0 0.071 12.9 0.2 4.5 5 0 0 5 5 5 2 Kelch motif HEAT PF02985.17 ETO23705.1 - 3.7e-07 29.6 0.7 0.00025 20.8 0.0 3.3 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.1 ETO23705.1 - 1.8e-05 24.8 0.0 0.23 11.7 0.0 3.3 2 1 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 ETO23705.1 - 0.00034 21.0 0.1 1.5 9.3 0.0 4.0 2 1 1 3 3 3 2 HEAT-like repeat Fe-ADH_2 PF13685.1 ETO23705.1 - 0.0098 15.2 0.0 0.033 13.4 0.0 1.8 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase TFCD_C PF12612.3 ETO23705.1 - 0.019 14.4 0.1 0.098 12.0 0.0 2.2 2 1 0 2 2 2 0 Tubulin folding cofactor D C terminal Adaptin_N PF01602.15 ETO23705.1 - 0.021 13.1 0.0 0.15 10.3 0.0 2.1 1 1 0 1 1 1 0 Adaptin N terminal region DUF445 PF04286.7 ETO23705.1 - 0.17 11.4 0.1 7.6 5.9 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF445) P16-Arc PF04699.9 ETO23706.1 - 7e-17 61.8 0.1 9e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.7 ETO23706.1 - 0.004 17.0 0.0 0.019 14.8 0.0 1.9 2 0 0 2 2 2 1 Dip2/Utp12 Family WD40 PF00400.27 ETO23709.1 - 3.4e-79 258.1 19.4 3.5e-12 45.6 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO23709.1 - 2.1e-14 53.6 0.1 7.1e-05 22.5 0.0 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO23709.1 - 1.7e-07 29.8 2.9 0.058 11.5 0.1 4.0 1 1 3 4 4 4 3 Nucleoporin Nup120/160 PD40 PF07676.7 ETO23709.1 - 1.2e-05 24.8 12.8 7 6.4 0.1 6.9 7 0 0 7 7 7 3 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO23709.1 - 4.7e-05 22.3 5.9 0.22 10.2 0.1 4.5 1 1 1 3 3 3 2 Nup133 N terminal like DPPIV_N PF00930.16 ETO23709.1 - 9.3e-05 21.1 0.0 0.038 12.5 0.0 3.6 3 1 1 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Proteasome_A_N PF10584.4 ETO23709.1 - 0.00029 20.1 4.4 17 4.8 0.0 5.7 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature Cytochrom_D1 PF02239.11 ETO23709.1 - 0.001 17.4 0.2 0.59 8.3 0.0 3.3 1 1 3 4 4 4 2 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO23709.1 - 0.0039 16.3 0.8 6.4 5.7 0.0 3.6 2 1 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PLD_C PF12357.3 ETO23709.1 - 0.016 14.6 0.1 21 4.7 0.0 3.9 2 1 2 4 4 4 0 Phospholipase D C terminal Resistin PF06954.6 ETO23709.1 - 0.031 14.5 2.2 30 4.9 0.0 4.4 4 1 2 6 6 6 0 Resistin GRIN_C PF15235.1 ETO23710.1 - 8.1 6.5 7.2 0.96 9.5 0.7 2.0 1 1 1 2 2 2 0 G protein-regulated inducer of neurite outgrowth C-terminus SAM_1 PF00536.25 ETO23711.1 - 7.8e-12 45.1 0.6 2.3e-11 43.6 0.1 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO23711.1 - 7.9e-11 41.6 0.2 2.5e-10 40.0 0.1 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IncA PF04156.9 ETO23711.1 - 0.043 13.4 47.9 0.081 12.5 13.2 4.1 3 1 1 4 4 4 0 IncA protein Prominin PF05478.6 ETO23711.1 - 0.083 10.4 21.1 0.019 12.5 10.4 2.0 2 0 0 2 2 2 0 Prominin BCDHK_Adom3 PF10436.4 ETO23711.1 - 0.1 12.0 9.2 0.068 12.6 2.8 2.8 2 1 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase LMBR1 PF04791.11 ETO23711.1 - 0.41 9.1 10.4 0.52 8.8 7.2 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein 60KD_IMP PF02096.15 ETO23711.1 - 1.9 8.1 8.2 70 2.9 5.6 2.7 1 1 0 1 1 1 0 60Kd inner membrane protein WXG100 PF06013.7 ETO23711.1 - 2.8 8.0 21.4 0.94 9.5 5.6 3.8 4 0 0 4 4 4 0 Proteins of 100 residues with WXG SAM_1 PF00536.25 ETO23712.1 - 8.3e-13 48.3 0.2 1.5e-12 47.4 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO23712.1 - 2e-09 37.1 0.1 3.4e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DivIVA PF05103.8 ETO23712.1 - 0.02 14.9 3.2 0.02 14.9 2.2 2.4 1 1 1 2 2 2 0 DivIVA protein IncA PF04156.9 ETO23712.1 - 0.046 13.3 5.4 0.059 12.9 3.7 1.2 1 0 0 1 1 1 0 IncA protein Bap31 PF05529.7 ETO23712.1 - 0.12 11.8 3.1 0.19 11.1 2.1 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF948 PF06103.6 ETO23712.1 - 0.15 11.9 1.6 0.58 10.0 0.5 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Phage_Gp23 PF10669.4 ETO23712.1 - 0.19 11.8 3.9 0.3 11.1 2.7 1.4 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DUF4363 PF14276.1 ETO23712.1 - 0.23 11.1 4.3 0.32 10.6 2.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4363) APG6 PF04111.7 ETO23712.1 - 0.23 10.4 8.3 0.29 10.1 5.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Cob_adeno_trans PF01923.13 ETO23712.1 - 0.34 10.6 2.6 0.55 9.9 1.8 1.3 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Atg14 PF10186.4 ETO23712.1 - 0.46 9.3 8.7 0.15 10.9 4.4 1.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Borrelia_P83 PF05262.6 ETO23712.1 - 0.63 8.2 9.2 0.78 7.9 6.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF342 PF03961.8 ETO23712.1 - 1.6 7.0 9.4 2.1 6.6 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Seryl_tRNA_N PF02403.17 ETO23712.1 - 9.7 6.2 13.9 7.2 6.6 8.3 1.7 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF904 PF06005.7 ETO23713.1 - 0.012 15.9 0.7 0.012 15.9 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF904) HTH_1 PF00126.22 ETO23714.1 - 0.13 12.0 0.2 0.33 10.7 0.2 1.6 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family PTR2 PF00854.16 ETO23716.1 - 2.3e-20 72.7 2.0 2.3e-20 72.7 1.4 1.3 2 0 0 2 2 2 1 POT family DUF872 PF05915.7 ETO23716.1 - 0.2 11.5 5.9 1.6 8.5 0.8 3.0 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) dNK PF01712.14 ETO23718.1 - 8.6e-24 84.1 1.4 1.4e-23 83.4 1.0 1.4 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_33 PF13671.1 ETO23718.1 - 0.00097 19.0 0.3 0.016 15.0 0.2 2.3 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 ETO23718.1 - 0.0014 18.0 0.1 0.051 12.9 0.2 2.6 2 1 0 2 2 2 1 Thymidylate kinase DUF1268 PF06896.6 ETO23718.1 - 0.01 16.1 1.5 0.02 15.2 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1268) DUF2305 PF10230.4 ETO23718.1 - 0.018 14.4 0.2 0.029 13.7 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) AAA_18 PF13238.1 ETO23718.1 - 0.02 15.2 0.5 0.5 10.6 0.2 2.5 1 1 0 1 1 1 0 AAA domain Herpes_TK PF00693.13 ETO23718.1 - 0.035 13.2 1.1 0.57 9.3 0.0 2.7 3 0 0 3 3 3 0 Thymidine kinase from herpesvirus DUF1510 PF07423.6 ETO23719.1 - 6.4e-06 25.7 4.2 6.4e-06 25.7 2.9 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1510) ETRAMP PF09716.5 ETO23719.1 - 0.012 15.5 0.0 1.8 8.6 0.0 3.5 2 2 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) LMBR1 PF04791.11 ETO23719.1 - 0.17 10.4 3.2 0.19 10.3 0.1 2.2 1 1 1 2 2 2 0 LMBR1-like membrane protein EST1 PF10374.4 ETO23719.1 - 1 9.3 12.3 0.51 10.3 1.6 3.4 2 1 1 3 3 3 0 Telomerase activating protein Est1 NPR3 PF03666.8 ETO23720.1 - 6.9 5.0 13.0 0.13 10.7 3.0 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4414 PF14377.1 ETO23721.1 - 4.3e-05 23.3 12.2 0.00014 21.7 8.5 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4414) Ndc1_Nup PF09531.5 ETO23721.1 - 0.21 9.9 1.4 0.22 9.9 1.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BAF1_ABF1 PF04684.8 ETO23721.1 - 0.42 9.4 5.9 0.48 9.2 4.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF3484 PF11983.3 ETO23721.1 - 3.5 8.5 7.8 2.9 8.8 3.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3484) GET2 PF08690.5 ETO23721.1 - 4.5 6.4 6.2 5.5 6.1 4.3 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 DUF4175 PF13779.1 ETO23721.1 - 7.7 4.0 14.0 8.9 3.8 9.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Shisa PF13908.1 ETO23721.1 - 7.7 6.6 8.0 12 6.0 5.6 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DDHD PF02862.12 ETO23722.1 - 0.69 9.6 6.0 1 9.1 4.1 1.3 1 0 0 1 1 1 0 DDHD domain SAP PF02037.22 ETO23723.1 - 1.1e-08 34.3 5.6 2.6e-08 33.1 3.9 1.7 1 0 0 1 1 1 1 SAP domain Trypan_PARP PF05887.6 ETO23724.1 - 2.1e-05 24.3 27.7 2.7e-05 23.9 19.2 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DUF4551 PF15087.1 ETO23724.1 - 1.3 7.2 6.7 1.5 7.1 4.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Neisseria_TspB PF05616.8 ETO23724.1 - 5.2 5.3 13.4 6.1 5.0 9.3 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF2890 PF11081.3 ETO23724.1 - 7.6 6.5 15.0 9.9 6.1 10.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) GBP_C PF02841.9 ETO23725.1 - 0.0095 15.1 21.0 0.014 14.6 14.6 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain ADIP PF11559.3 ETO23725.1 - 0.018 14.9 4.4 0.018 14.9 3.0 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Herpes_env PF01673.13 ETO23725.1 - 0.17 10.4 8.1 0.19 10.2 5.6 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Cytomega_UL84 PF06284.6 ETO23725.1 - 0.3 9.4 6.0 0.35 9.2 4.2 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Suc_Fer-like PF06999.7 ETO23725.1 - 1.4 8.8 8.5 2.1 8.3 5.9 1.3 1 1 0 1 1 1 0 Sucrase/ferredoxin-like Trypan_PARP PF05887.6 ETO23725.1 - 5.3 6.8 8.7 7.9 6.2 6.1 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GRP PF07172.6 ETO23725.1 - 6.6 7.2 9.7 30 5.1 4.5 2.8 2 1 0 2 2 2 0 Glycine rich protein family BSMAP PF12280.3 ETO23725.1 - 6.6 6.5 9.1 9.7 6.0 6.3 1.3 1 0 0 1 1 1 0 Brain specific membrane anchored protein DUF4472 PF14739.1 ETO23726.1 - 0.0029 18.0 3.5 0.045 14.1 0.7 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4472) DUF3645 PF12359.3 ETO23726.1 - 0.07 12.2 0.2 0.12 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3645) Cep57_CLD_2 PF14197.1 ETO23726.1 - 0.55 10.2 9.9 9.1 6.3 0.1 2.9 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 Nup54 PF13874.1 ETO23726.1 - 1.2 8.8 6.0 4 7.1 1.1 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Daxx PF03344.10 ETO23727.1 - 0.023 13.1 9.5 0.025 13.0 6.6 1.0 1 0 0 1 1 1 0 Daxx Family TRAP_alpha PF03896.11 ETO23727.1 - 0.1 11.6 5.8 0.1 11.5 4.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.7 ETO23727.1 - 0.11 10.4 7.9 0.11 10.4 5.5 1.0 1 0 0 1 1 1 0 Nop14-like family BNIP2 PF12496.3 ETO23727.1 - 0.17 12.0 2.6 0.19 11.9 1.8 1.1 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 RRN3 PF05327.6 ETO23727.1 - 0.18 9.8 2.6 0.18 9.8 1.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Tom37_C PF11801.3 ETO23727.1 - 0.21 11.4 1.2 0.23 11.3 0.8 1.1 1 0 0 1 1 1 0 Tom37 C-terminal domain YL1 PF05764.8 ETO23727.1 - 0.23 11.0 9.1 0.25 10.9 6.3 1.1 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.7 ETO23727.1 - 0.34 10.1 8.5 0.37 10.0 5.9 1.1 1 0 0 1 1 1 0 SDA1 Inhibitor_I53 PF11714.3 ETO23727.1 - 0.74 9.8 5.1 1 9.4 3.5 1.2 1 0 0 1 1 1 0 Thrombin inhibitor Madanin DUF2890 PF11081.3 ETO23727.1 - 0.96 9.4 6.9 1.1 9.3 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) zf-RanBP PF00641.13 ETO23728.1 - 0.091 11.8 2.9 0.18 10.9 2.0 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others DUF641 PF04859.7 ETO23728.1 - 3.3 7.4 14.8 2.8 7.7 0.6 3.1 3 1 1 4 4 4 0 Plant protein of unknown function (DUF641) CBM_48 PF02922.13 ETO23731.1 - 0.053 13.5 0.2 0.099 12.6 0.1 1.4 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Flt3_lig PF02947.9 ETO23731.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 flt3 ligand Mistic PF11458.3 ETO23732.1 - 0.13 12.6 2.4 0.3 11.5 0.1 2.4 2 0 0 2 2 2 0 Membrane-integrating protein Mistic MGC-24 PF05283.6 ETO23732.1 - 1.1 8.9 7.7 0.63 9.8 0.3 2.2 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) DUF4446 PF14584.1 ETO23732.1 - 6.1 6.6 7.3 12 5.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) vATP-synt_E PF01991.13 ETO23733.1 - 5.3e-16 58.4 0.4 6.2e-16 58.2 0.3 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit OSCP PF00213.13 ETO23733.1 - 0.004 17.0 0.3 0.005 16.7 0.2 1.2 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Pkinase PF00069.20 ETO23735.1 - 7.5e-41 139.9 0.5 1.2e-40 139.3 0.3 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO23735.1 - 6.2e-25 87.7 0.2 8.8e-25 87.2 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETO23735.1 - 0.00082 19.1 0.2 0.088 12.5 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family DUF848 PF05852.6 ETO23735.1 - 0.007 16.2 2.0 0.012 15.5 0.1 2.0 2 0 0 2 2 2 1 Gammaherpesvirus protein of unknown function (DUF848) Syntaxin PF00804.20 ETO23735.1 - 2.8 8.1 7.3 15 5.8 1.8 2.4 2 0 0 2 2 2 0 Syntaxin TBD PF12845.2 ETO23735.1 - 3.6 7.1 7.1 46 3.6 3.2 2.9 2 1 0 2 2 2 0 TBD domain zf-C2H2 PF00096.21 ETO23736.1 - 5.9e-12 45.1 19.7 1e-05 25.5 0.2 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETO23736.1 - 1e-10 41.3 15.9 1.5e-08 34.5 1.1 3.3 4 0 0 4 4 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 ETO23736.1 - 1e-09 38.0 17.6 0.00066 19.8 0.2 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-BED PF02892.10 ETO23736.1 - 0.0006 19.5 14.0 0.42 10.4 1.1 3.6 2 1 1 3 3 3 3 BED zinc finger zf-met PF12874.2 ETO23736.1 - 0.0017 18.4 15.3 0.21 11.8 0.1 3.9 4 0 0 4 4 4 3 Zinc-finger of C2H2 type DUF4187 PF13821.1 ETO23736.1 - 0.0042 16.6 1.8 0.01 15.4 1.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) XPA_N PF01286.13 ETO23736.1 - 0.02 14.5 1.0 4.7 6.9 0.0 2.6 2 0 0 2 2 2 0 XPA protein N-terminal zf-C2H2_6 PF13912.1 ETO23736.1 - 0.3 11.0 13.4 0.57 10.1 0.5 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 ETO23736.1 - 0.68 9.6 0.1 0.68 9.6 0.0 2.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 ETO23736.1 - 1.6 8.9 17.0 0.49 10.5 0.2 3.9 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 ETO23736.1 - 2.4 8.2 12.9 8 6.6 0.4 3.6 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) HECT PF00632.20 ETO23737.1 - 6.6e-71 239.0 0.0 1.4e-69 234.7 0.0 2.4 1 1 1 2 2 2 1 HECT-domain (ubiquitin-transferase) Neisseria_TspB PF05616.8 ETO23737.1 - 0.49 8.7 5.7 0.69 8.2 4.0 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein RIC3 PF15361.1 ETO23737.1 - 2.8 8.1 8.0 8.4 6.6 5.6 1.8 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Presenilin PF01080.12 ETO23737.1 - 9.7 4.8 7.1 27 3.4 4.9 1.7 1 1 0 1 1 1 0 Presenilin PX PF00787.19 ETO23738.1 - 6.4e-08 32.3 0.8 1e-07 31.7 0.5 1.4 1 0 0 1 1 1 1 PX domain DNA_pol_E_B PF04042.11 ETO23739.1 - 4.9e-42 143.5 1.8 8.5e-42 142.7 1.2 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Dpoe2NT PF12213.3 ETO23739.1 - 3e-05 23.8 0.0 7.3e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 DNA polymerases epsilon N terminal DUF1510 PF07423.6 ETO23740.1 - 0.0019 17.6 11.6 0.0029 17.0 8.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) START PF01852.14 ETO23741.1 - 2.7e-14 52.9 0.2 1.3e-10 40.9 0.1 2.4 2 0 0 2 2 2 2 START domain DDHD PF02862.12 ETO23741.1 - 1.7 8.4 13.7 0.85 9.3 3.6 3.0 3 0 0 3 3 3 0 DDHD domain Menin PF05053.8 ETO23741.1 - 2.2 6.3 18.5 0.014 13.6 6.9 1.5 2 0 0 2 2 2 0 Menin START PF01852.14 ETO23742.1 - 1.6e-07 30.8 0.0 2.5e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 START domain RCC1 PF00415.13 ETO23744.1 - 2.4e-10 40.4 1.0 0.00043 20.4 0.0 2.3 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO23744.1 - 4.5e-05 22.9 0.3 0.053 13.1 0.1 2.4 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat Integrin_alpha2 PF08441.7 ETO23744.1 - 0.026 13.3 0.1 0.034 12.9 0.1 1.2 1 0 0 1 1 1 0 Integrin alpha AAA_17 PF13207.1 ETO23745.1 - 0.18 12.5 1.6 0.22 12.3 1.1 1.4 1 1 0 1 1 1 0 AAA domain PTB PF08416.8 ETO23746.1 - 0.071 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotyrosine-binding domain EIIBC-GUT_N PF03612.9 ETO23747.1 - 0.37 10.3 6.2 0.45 10.1 4.3 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Pinin_SDK_memA PF04696.8 ETO23747.1 - 0.59 9.7 25.0 0.7 9.4 17.3 1.1 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region DUF2052 PF09747.4 ETO23747.1 - 0.75 9.7 10.1 0.87 9.4 7.0 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF3408 PF11888.3 ETO23747.1 - 0.82 9.5 10.9 1.2 9.0 7.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Paramyxo_ncap PF00973.14 ETO23747.1 - 6.2 5.4 10.2 6.6 5.3 7.0 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Hom_end_hint PF05203.11 ETO23747.1 - 8.9 5.9 10.1 9.9 5.8 7.0 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint Pyr_redox_3 PF13738.1 ETO23748.1 - 1.2e-16 61.3 0.0 2.2e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETO23748.1 - 2.2e-12 46.0 0.2 1.1e-11 43.6 0.1 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 ETO23748.1 - 1.1e-08 34.3 0.7 1.9e-08 33.5 0.1 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 ETO23748.1 - 1e-07 32.0 0.0 1.3e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETO23748.1 - 0.00011 21.9 2.3 0.17 11.6 2.2 3.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 ETO23748.1 - 0.0023 18.2 3.3 2 8.8 0.2 3.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETO23748.1 - 0.027 13.3 2.7 0.23 10.3 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 ETO23748.1 - 0.027 13.3 0.1 0.95 8.3 0.2 2.3 2 1 0 2 2 2 0 Lycopene cyclase protein Connexin PF00029.14 ETO23750.1 - 0.0074 16.3 0.8 0.016 15.2 0.2 1.7 1 1 1 2 2 2 1 Connexin AXE1 PF05448.7 ETO23750.1 - 0.04 12.4 1.7 0.048 12.1 1.2 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Herpes_UL49_2 PF04823.7 ETO23750.1 - 0.057 13.4 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL49 tegument protein YolD PF08863.5 ETO23750.1 - 0.09 12.6 8.2 0.065 13.0 0.9 2.5 2 0 0 2 2 2 0 YolD-like protein Hat1_N PF10394.4 ETO23751.1 - 2.7e-05 24.2 0.1 2.7e-05 24.2 0.1 1.7 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_7 PF13508.1 ETO23751.1 - 0.0013 18.8 0.0 0.0029 17.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 ETO23751.1 - 0.0057 15.9 0.8 0.0084 15.3 0.5 1.3 1 0 0 1 1 1 1 MOZ/SAS family Mec-17 PF05301.6 ETO23751.1 - 0.015 15.2 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Touch receptor neuron protein Mec-17 Acetyltransf_1 PF00583.19 ETO23751.1 - 0.017 15.1 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 ETO23751.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Herpes_UL51 PF04540.8 ETO23752.1 - 0.11 12.0 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL51 protein DUF4120 PF13496.1 ETO23752.1 - 0.29 11.1 1.6 9.4 6.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4120) Cyclin_N PF00134.18 ETO23753.1 - 2.4e-31 107.9 1.3 5.7e-31 106.7 0.9 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 ETO23753.1 - 9.8e-22 77.1 0.2 1.9e-21 76.1 0.2 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Macoilin PF09726.4 ETO23754.1 - 0.1 10.8 15.3 0.12 10.6 10.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Raftlin PF15250.1 ETO23754.1 - 0.22 9.9 15.9 0.3 9.5 11.0 1.1 1 0 0 1 1 1 0 Raftlin Ndc1_Nup PF09531.5 ETO23754.1 - 0.26 9.6 7.5 0.27 9.6 5.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAM60A PF15396.1 ETO23754.1 - 0.28 10.9 11.0 0.43 10.2 7.6 1.4 1 0 0 1 1 1 0 Protein Family FAM60A SprA-related PF12118.3 ETO23754.1 - 0.31 10.3 19.3 0.37 10.0 13.3 1.1 1 0 0 1 1 1 0 SprA-related family DUF3527 PF12043.3 ETO23754.1 - 0.93 8.9 14.1 1.2 8.6 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) Utp14 PF04615.8 ETO23754.1 - 1.6 6.7 27.9 2.1 6.4 19.3 1.1 1 0 0 1 1 1 0 Utp14 protein Hid1 PF12722.2 ETO23754.1 - 2.9 5.4 30.2 3.7 5.1 20.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Mem_trans PF03547.13 ETO23754.1 - 3.1 5.9 7.3 3.6 5.7 5.1 1.2 1 0 0 1 1 1 0 Membrane transport protein DUF605 PF04652.11 ETO23754.1 - 7.9 5.7 21.0 10 5.3 14.6 1.1 1 0 0 1 1 1 0 Vta1 like NPR3 PF03666.8 ETO23754.1 - 9.3 4.6 15.6 15 4.0 10.8 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF830 PF05708.7 ETO23755.1 - 0.075 13.0 0.4 0.11 12.4 0.2 1.4 1 1 0 1 1 1 0 Orthopoxvirus protein of unknown function (DUF830) Striatin PF08232.7 ETO23756.1 - 0.00011 22.4 5.5 0.00023 21.4 3.8 1.5 1 0 0 1 1 1 1 Striatin family bZIP_1 PF00170.16 ETO23756.1 - 0.058 13.3 2.3 0.16 11.9 1.6 1.8 1 0 0 1 1 1 0 bZIP transcription factor SNAPc19 PF15497.1 ETO23756.1 - 0.085 13.0 6.6 0.19 11.9 4.6 1.6 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 AATF-Che1 PF13339.1 ETO23756.1 - 0.14 12.3 8.4 0.048 13.8 3.9 1.6 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor DivIC PF04977.10 ETO23756.1 - 1.3 8.5 6.1 1.4 8.4 0.6 2.4 2 0 0 2 2 2 0 Septum formation initiator DUF904 PF06005.7 ETO23756.1 - 5.9 7.2 9.1 23 5.3 6.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF3086 PF11285.3 ETO23757.1 - 0.13 11.1 5.0 0.19 10.4 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) zf-TAZ PF02135.11 ETO23757.1 - 2.4 8.2 14.6 5.2 7.1 2.0 3.3 3 0 0 3 3 3 0 TAZ zinc finger Tyrosinase PF00264.15 ETO23759.1 - 1.1e-20 74.7 1.7 2.2e-20 73.7 1.2 1.5 1 0 0 1 1 1 1 Common central domain of tyrosinase Haemocyan_bet_s PF14830.1 ETO23759.1 - 7.4e-07 28.8 0.0 2.3e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Haemocyanin beta-sandwich TPR_MLP1_2 PF07926.7 ETO23760.1 - 0.033 13.9 29.8 0.069 12.9 15.2 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.2 ETO23760.1 - 0.063 13.1 26.9 0.022 14.6 13.4 2.3 2 0 0 2 2 2 0 Tropomyosin like LXG PF04740.7 ETO23760.1 - 0.091 12.5 18.1 0.095 12.4 4.7 2.2 1 1 1 2 2 2 0 LXG domain of WXG superfamily GAS PF13851.1 ETO23760.1 - 0.84 8.7 33.6 0.045 12.9 1.7 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4201 PF13870.1 ETO23760.1 - 1.6 8.1 25.1 1 8.7 8.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Pepsin-I3 PF06394.8 ETO23760.1 - 2.4 7.8 5.6 12 5.6 0.2 2.8 1 1 1 2 2 2 0 Pepsin inhibitor-3-like repeated domain Pox_A_type_inc PF04508.7 ETO23760.1 - 3.5 7.6 8.9 23 5.1 0.3 4.1 3 1 0 3 3 3 0 Viral A-type inclusion protein repeat MxiH PF09392.5 ETO23760.1 - 6 7.5 11.0 2.1e+02 2.5 7.5 2.5 1 1 0 1 1 1 0 Type III secretion needle MxiH like TPR_11 PF13414.1 ETO23761.1 - 8.1e-07 28.5 0.7 0.00014 21.4 0.1 2.6 2 0 0 2 2 2 1 TPR repeat TPR_17 PF13431.1 ETO23761.1 - 0.0024 17.9 1.0 0.0063 16.6 0.0 2.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO23761.1 - 0.0039 16.9 2.5 0.58 10.2 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO23761.1 - 0.02 15.4 0.8 0.77 10.5 0.0 3.4 4 1 1 5 5 5 0 Tetratricopeptide repeat ChAPs PF09295.5 ETO23761.1 - 0.033 12.9 0.1 0.054 12.2 0.1 1.2 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_1 PF00515.23 ETO23761.1 - 0.053 13.1 1.3 3.3 7.4 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4525 PF15027.1 ETO23761.1 - 0.096 12.2 1.2 0.34 10.4 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) TPR_8 PF13181.1 ETO23761.1 - 0.17 11.7 1.6 1.5 8.7 0.0 2.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETO23761.1 - 0.24 11.3 1.7 0.71 9.8 0.0 2.6 4 0 0 4 4 4 0 Tetratricopeptide repeat PUB PF09409.5 ETO23762.1 - 9.3e-08 31.7 0.1 2e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 PUB domain His_Phos_1 PF00300.17 ETO23762.1 - 0.0012 18.9 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Plasmodium_Vir PF05795.6 ETO23762.1 - 0.0015 17.8 1.7 0.0015 17.8 1.2 1.6 2 0 0 2 2 2 1 Plasmodium vivax Vir protein MMPL PF03176.10 ETO23763.1 - 5.6e-13 48.3 8.3 7.5e-13 47.8 5.8 1.1 1 0 0 1 1 1 1 MMPL family CopD PF05425.8 ETO23763.1 - 0.31 11.2 7.7 0.31 11.2 4.2 1.9 1 1 1 2 2 2 0 Copper resistance protein D UPF0182 PF03699.8 ETO23763.1 - 3.5 5.4 7.1 4.8 4.9 5.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF2157 PF09925.4 ETO23763.1 - 4.5 6.8 8.1 47 3.5 5.6 2.2 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) Intron_maturas2 PF01348.16 ETO23764.1 - 0.059 13.3 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Type II intron maturase SLA_LP_auto_ag PF05889.8 ETO23764.1 - 0.069 11.6 0.1 0.077 11.4 0.1 1.1 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) DUF4208 PF13907.1 ETO23764.1 - 0.12 12.5 0.1 0.24 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) CAP_GLY PF01302.20 ETO23765.1 - 1.6e-11 43.7 0.3 3.6e-11 42.5 0.2 1.5 1 0 0 1 1 1 1 CAP-Gly domain RPEL PF02755.10 ETO23765.1 - 0.0054 16.0 2.1 0.006 15.8 0.3 2.0 2 0 0 2 2 2 1 RPEL repeat ANF_receptor PF01094.23 ETO23765.1 - 0.024 13.4 0.1 0.038 12.7 0.1 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region Baculo_LEF-2 PF03041.9 ETO23765.1 - 0.026 14.2 1.6 0.052 13.2 1.1 1.4 1 0 0 1 1 1 0 lef-2 RasGEF PF00617.14 ETO23766.1 - 3.7e-47 160.4 0.5 7.4e-47 159.5 0.4 1.5 1 0 0 1 1 1 1 RasGEF domain DUF2807 PF10988.3 ETO23767.1 - 0.0087 15.6 3.3 0.0087 15.6 2.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2807) SR-25 PF10500.4 ETO23767.1 - 0.13 11.7 15.7 0.2 11.0 10.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1117 PF06547.7 ETO23767.1 - 1.8 8.7 7.7 4.9 7.2 5.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) Glutaredoxin PF00462.19 ETO23770.1 - 2e-07 30.8 0.0 4.8e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin PT-HINT PF07591.6 ETO23770.1 - 0.055 13.3 0.1 0.16 11.8 0.0 1.7 1 1 0 1 1 1 0 Pretoxin HINT domain G-patch_2 PF12656.2 ETO23770.1 - 0.064 13.1 0.1 0.7 9.7 0.0 2.7 4 0 0 4 4 4 0 DExH-box splicing factor binding site MIP-T3 PF10243.4 ETO23773.1 - 0.65 8.3 35.1 0.75 8.1 24.3 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF4023 PF13215.1 ETO23775.1 - 0.31 10.8 1.7 0.55 10.0 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4023) ARID PF01388.16 ETO23776.1 - 0.0075 16.1 0.1 0.013 15.3 0.1 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DBB PF14545.1 ETO23776.1 - 0.19 11.2 2.1 3.1 7.2 0.1 2.1 2 0 0 2 2 2 0 Dof, BCAP, and BANK (DBB) motif, Y2_Tnp PF04986.8 ETO23777.1 - 0.0022 17.7 0.3 0.0033 17.1 0.2 1.3 1 0 0 1 1 1 1 Putative transposase CBM_21 PF03370.8 ETO23778.1 - 0.0048 16.8 0.2 0.0097 15.8 0.2 1.5 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit Senescence_reg PF04520.8 ETO23779.1 - 0.093 13.2 10.7 0.11 12.9 7.4 1.1 1 0 0 1 1 1 0 Senescence regulator AUX_IAA PF02309.11 ETO23779.1 - 0.35 10.5 7.7 0.43 10.2 5.3 1.1 1 0 0 1 1 1 0 AUX/IAA family Pneumo_att_G PF05539.6 ETO23779.1 - 1.1 8.5 11.6 1.4 8.2 8.1 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Dicty_REP PF05086.7 ETO23779.1 - 2.5 5.7 7.8 2.7 5.6 5.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SOBP PF15279.1 ETO23779.1 - 3.5 7.9 7.6 4.1 7.6 5.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein SRP-alpha_N PF04086.8 ETO23779.1 - 9.4 5.5 14.1 12 5.1 9.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal UCH PF00443.24 ETO23780.1 - 2.8e-28 98.7 2.6 3.8e-28 98.3 1.8 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SAP PF02037.22 ETO23780.1 - 0.015 14.7 0.6 0.015 14.7 0.4 2.0 2 0 0 2 2 2 0 SAP domain Armet PF10208.4 ETO23780.1 - 0.064 12.9 0.1 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding Fer4_18 PF13746.1 ETO23781.1 - 7.5e-05 23.0 0.6 0.00076 19.8 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.1 ETO23781.1 - 0.00019 21.6 2.8 0.0071 16.6 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain DUF1201 PF06716.6 ETO23781.1 - 0.011 15.5 4.8 0.02 14.6 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1201) PKD_channel PF08016.7 ETO23781.1 - 0.059 11.7 0.1 0.077 11.4 0.0 1.2 1 0 0 1 1 1 0 Polycystin cation channel Fer4_8 PF13183.1 ETO23781.1 - 0.12 12.4 2.7 4.9 7.2 0.1 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain DUF1712 PF08217.6 ETO23781.1 - 0.12 10.5 0.0 0.16 10.1 0.0 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1712) MutS_V PF00488.16 ETO23782.1 - 1.5e-47 161.9 0.3 1e-20 74.1 0.0 3.4 3 0 0 3 3 3 3 MutS domain V MutS_III PF05192.13 ETO23783.1 - 8.4e-21 74.6 0.1 1.7e-20 73.6 0.0 1.6 2 0 0 2 2 2 1 MutS domain III Tubulin PF00091.20 ETO23785.1 - 9.7e-61 205.3 0.0 1.5e-60 204.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO23785.1 - 1.1e-33 115.9 0.1 1.7e-33 115.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Lipase_3 PF01764.20 ETO23785.1 - 0.0078 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) RGS PF00615.14 ETO23787.1 - 7e-05 22.9 0.6 8.4e-05 22.6 0.4 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain DAGK_cat PF00781.19 ETO23789.1 - 0.00086 18.7 0.0 0.0012 18.2 0.0 1.3 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF4131 PF13567.1 ETO23792.1 - 0.012 15.0 0.5 0.012 15.0 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) CAAD PF14159.1 ETO23792.1 - 0.057 13.0 0.1 0.057 13.0 0.1 2.4 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Vps52 PF04129.7 ETO23793.1 - 0.0085 14.6 3.9 0.013 14.0 2.7 1.2 1 0 0 1 1 1 1 Vps52 / Sac2 family TIR-like PF10137.4 ETO23793.1 - 0.054 13.1 1.1 0.13 11.8 0.8 1.6 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain Synaptonemal_3 PF15191.1 ETO23793.1 - 0.1 12.3 1.9 0.18 11.5 1.3 1.4 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 zf-CCCH PF00642.19 ETO23794.1 - 8.5e-09 34.8 13.6 0.00039 20.0 0.5 2.2 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Macoilin PF09726.4 ETO23794.1 - 0.29 9.3 4.8 0.32 9.2 3.3 1.0 1 0 0 1 1 1 0 Transmembrane protein Viral_Beta_CD PF04530.7 ETO23795.1 - 0.0042 17.2 1.5 0.26 11.4 2.2 2.4 2 0 0 2 2 2 1 Viral Beta C/D like family DCP2 PF05026.8 ETO23795.1 - 0.063 13.1 1.7 0.28 11.1 0.2 2.4 1 1 0 2 2 2 0 Dcp2, box A domain Spt5_N PF11942.3 ETO23795.1 - 5.7 7.6 16.9 1.9 9.1 9.5 1.8 1 1 1 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF912 PF06024.7 ETO23795.1 - 7.3 6.7 7.9 2.4e+02 1.8 0.0 3.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pkinase PF00069.20 ETO23796.1 - 4.3e-59 199.7 0.0 1.3e-53 181.7 0.0 2.9 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO23796.1 - 6.7e-28 97.4 0.0 3.8e-27 94.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETO23796.1 - 9.6e-06 25.4 0.1 0.0018 18.0 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 ETO23796.1 - 6.4e-05 22.0 0.0 0.0001 21.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETO23796.1 - 0.00016 20.8 0.0 0.00029 19.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kelch_1 PF01344.20 ETO23797.1 - 2.8e-08 33.1 2.4 8.4e-05 22.0 0.0 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO23797.1 - 6.5e-06 26.0 3.5 0.0045 17.1 0.0 4.1 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO23797.1 - 5.4e-05 22.8 1.1 0.019 14.7 0.0 3.7 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO23797.1 - 0.00012 21.9 2.3 3.1 7.8 0.2 5.0 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.1 ETO23797.1 - 0.014 15.5 1.1 0.089 12.9 0.0 3.0 5 0 0 5 5 5 0 Galactose oxidase, central domain PTEN_C2 PF10409.4 ETO23797.1 - 0.024 14.3 0.3 0.093 12.4 0.2 2.0 1 1 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein tRNA_Me_trans PF03054.11 ETO23797.1 - 0.028 12.9 2.2 0.072 11.6 0.3 2.0 2 0 0 2 2 2 0 tRNA methyl transferase Kelch_2 PF07646.10 ETO23797.1 - 0.32 10.8 7.8 5 7.0 0.1 4.5 4 1 1 5 5 5 0 Kelch motif WD40 PF00400.27 ETO23798.1 - 1.1e-65 215.2 24.8 5.7e-12 45.0 0.0 7.8 7 1 1 8 8 8 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO23798.1 - 5.4e-09 36.0 0.3 0.0054 16.4 0.0 3.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO23798.1 - 5.5e-07 28.2 0.3 0.034 12.4 0.0 3.1 3 0 0 3 3 3 2 Cytochrome D1 heme domain PD40 PF07676.7 ETO23798.1 - 5.7e-06 25.8 7.6 1.4 8.6 0.2 5.3 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 ETO23798.1 - 0.0017 17.0 0.0 0.77 8.2 0.0 3.5 1 1 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PQQ_2 PF13360.1 ETO23798.1 - 0.0021 17.5 0.1 0.21 10.9 0.0 2.9 1 1 2 3 3 3 1 PQQ-like domain Pectate_lyase22 PF14583.1 ETO23798.1 - 0.0026 16.2 0.0 0.4 9.0 0.0 2.2 1 1 0 2 2 2 2 Oligogalacturonate lyase Resistin PF06954.6 ETO23798.1 - 0.009 16.2 0.1 45 4.4 0.0 4.8 2 2 2 5 5 5 0 Resistin Proteasome_A_N PF10584.4 ETO23798.1 - 1.9 7.8 11.1 8.2 5.8 0.0 5.0 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature MutS_V PF00488.16 ETO23801.1 - 2.3e-60 203.9 0.1 3e-60 203.5 0.0 1.0 1 0 0 1 1 1 1 MutS domain V DUF3439 PF11921.3 ETO23803.1 - 7e-05 22.5 8.8 0.00032 20.4 0.9 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3439) CDC45 PF02724.9 ETO23803.1 - 6 4.7 8.5 7.8 4.3 1.3 2.3 2 1 0 2 2 2 0 CDC45-like protein LMBR1 PF04791.11 ETO23804.1 - 0.00045 18.9 0.4 0.0043 15.7 0.0 2.2 2 0 0 2 2 2 1 LMBR1-like membrane protein DUF2564 PF10819.3 ETO23808.1 - 0.0017 18.3 0.3 0.0063 16.6 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2564) RPAP3_C PF13877.1 ETO23808.1 - 0.17 11.8 3.7 0.19 11.7 1.3 2.0 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 EAP30 PF04157.11 ETO23808.1 - 0.59 9.2 9.3 0.43 9.6 3.5 2.1 1 1 1 2 2 2 0 EAP30/Vps36 family DUF603 PF04645.7 ETO23808.1 - 0.86 9.5 12.0 0.12 12.3 4.2 2.3 1 1 0 2 2 2 0 Protein of unknown function, DUF603 DUF607 PF04678.8 ETO23808.1 - 1.7 8.5 10.9 0.26 11.1 2.5 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF607 DUF4337 PF14235.1 ETO23808.1 - 3.4 7.4 9.0 1.2 9.0 2.8 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4337) ABC2_membrane_3 PF12698.2 ETO23810.1 - 0.0056 15.7 1.2 0.0065 15.5 0.8 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein 7tm_1 PF00001.16 ETO23810.1 - 0.036 13.2 0.6 0.044 12.9 0.4 1.3 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) TMEMspv1-c74-12 PF11044.3 ETO23810.1 - 0.048 13.2 0.7 0.048 13.2 0.5 2.4 2 1 1 3 3 3 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF912 PF06024.7 ETO23810.1 - 0.049 13.6 1.2 0.11 12.5 0.8 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) adh_short PF00106.20 ETO23811.1 - 3.4e-09 36.8 0.8 1.7e-06 28.0 0.6 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETO23811.1 - 8.4e-05 22.3 0.2 0.00028 20.5 0.1 1.7 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETO23811.1 - 0.0035 17.1 0.1 0.0054 16.5 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF2152 PF10222.4 ETO23811.1 - 0.021 13.0 0.2 0.025 12.8 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2152) Epimerase PF01370.16 ETO23811.1 - 0.074 12.4 0.8 0.89 8.9 0.6 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sel1 PF08238.7 ETO23812.1 - 1.4e-13 50.9 10.7 0.00021 21.7 0.0 7.6 8 0 0 8 8 8 3 Sel1 repeat TPR_11 PF13414.1 ETO23812.1 - 0.00031 20.3 2.0 0.013 15.1 0.0 3.4 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.1 ETO23812.1 - 0.039 14.6 1.0 3.1 8.5 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat GCS PF03074.11 ETO23812.1 - 0.11 11.5 0.8 0.63 9.0 0.0 2.0 2 0 0 2 2 2 0 Glutamate-cysteine ligase EamA PF00892.15 ETO23814.1 - 0.016 15.2 30.7 0.018 15.0 3.4 4.0 4 1 0 4 4 4 0 EamA-like transporter family Daxx PF03344.10 ETO23815.1 - 0.094 11.1 46.0 0.13 10.7 31.9 1.2 1 0 0 1 1 1 0 Daxx Family SSP160 PF06933.6 ETO23815.1 - 1.6 6.5 10.4 2.2 6.1 7.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 NIF PF03031.13 ETO23816.1 - 2.2e-16 59.9 0.0 2.4e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Proteasome PF00227.21 ETO23818.1 - 3.9e-40 137.1 0.0 6.4e-40 136.4 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 ETO23818.1 - 8.4e-16 56.9 0.1 1.5e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature AAA_2 PF07724.9 ETO23819.1 - 5.5e-44 150.0 0.1 1.5e-43 148.6 0.1 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Ank_2 PF12796.2 ETO23819.1 - 4.9e-16 58.8 0.0 2.1e-09 37.5 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETO23819.1 - 5.3e-16 57.5 0.0 9.8e-06 25.1 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 ETO23819.1 - 3.9e-14 51.3 0.0 0.00028 20.8 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat ClpB_D2-small PF10431.4 ETO23819.1 - 1.2e-11 44.3 0.7 3e-11 43.0 0.0 2.2 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein Ank_4 PF13637.1 ETO23819.1 - 3.9e-11 43.1 0.0 0.0002 21.7 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) AAA_5 PF07728.9 ETO23819.1 - 9e-11 41.6 0.0 3.9e-10 39.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Ank_5 PF13857.1 ETO23819.1 - 1e-09 38.2 0.1 0.026 14.7 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Sigma54_activat PF00158.21 ETO23819.1 - 3.1e-07 30.0 0.0 5.9e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.24 ETO23819.1 - 6.3e-07 29.6 0.0 1.8e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Torsin PF06309.6 ETO23819.1 - 5.6e-05 23.0 0.0 0.00024 20.9 0.0 2.0 2 0 0 2 2 2 1 Torsin AAA_16 PF13191.1 ETO23819.1 - 0.00035 20.6 0.0 0.0014 18.6 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 ETO23819.1 - 0.00048 19.2 0.0 0.0012 17.9 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 ETO23819.1 - 0.0009 18.4 0.0 0.025 13.7 0.0 2.3 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 ETO23819.1 - 0.0019 17.8 0.0 0.02 14.4 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETO23819.1 - 0.004 17.2 0.0 0.021 14.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETO23819.1 - 0.0055 16.5 0.1 0.72 9.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETO23819.1 - 0.017 15.4 0.2 0.14 12.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 ETO23819.1 - 0.027 15.2 1.8 0.14 13.0 0.0 3.1 4 1 0 4 4 2 0 AAA domain RNA_helicase PF00910.17 ETO23819.1 - 0.054 13.6 0.1 0.44 10.7 0.0 2.4 2 0 0 2 2 2 0 RNA helicase MobB PF03205.9 ETO23819.1 - 0.062 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RRS1 PF04939.7 ETO23819.1 - 0.069 12.6 0.1 0.069 12.6 0.1 2.5 2 0 0 2 2 2 0 Ribosome biogenesis regulatory protein (RRS1) ABC_tran PF00005.22 ETO23819.1 - 0.07 13.4 0.1 0.28 11.5 0.0 2.1 2 0 0 2 2 1 0 ABC transporter SRP54 PF00448.17 ETO23819.1 - 0.086 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF258 PF03193.11 ETO23819.1 - 0.094 11.9 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 WD40 PF00400.27 ETO23821.1 - 3.2e-48 159.9 12.5 3.8e-10 39.2 0.0 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO23821.1 - 1.2e-09 37.9 8.0 5.7e-05 23.1 0.1 5.7 6 1 0 6 6 6 2 Kelch motif Kelch_1 PF01344.20 ETO23821.1 - 5.1e-08 32.3 2.3 0.00021 20.7 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO23821.1 - 1.5e-06 27.8 3.7 0.00035 20.2 0.1 4.3 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO23821.1 - 5.9e-06 25.8 5.0 0.0089 15.7 0.1 5.4 6 0 0 6 6 6 1 Kelch motif Kelch_3 PF13415.1 ETO23821.1 - 6.5e-06 26.1 0.4 0.0013 18.8 0.0 4.0 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO23821.1 - 7e-05 22.6 0.6 0.044 13.7 0.1 3.4 2 0 0 2 2 2 1 Kelch motif PD40 PF07676.7 ETO23821.1 - 0.0049 16.4 2.0 11 5.8 0.0 4.6 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO23821.1 - 0.0059 15.4 5.6 0.0081 14.9 0.2 2.7 2 1 1 3 3 3 1 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO23821.1 - 0.018 13.3 0.1 0.91 7.7 0.0 2.9 3 0 0 3 3 3 0 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 ETO23821.1 - 3.1 7.1 10.3 16 4.9 0.0 4.8 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Kelch_5 PF13854.1 ETO23822.1 - 0.013 15.4 0.2 0.075 13.0 0.0 2.2 2 0 0 2 2 2 0 Kelch motif Kelch_6 PF13964.1 ETO23822.1 - 0.015 15.4 0.2 0.23 11.6 0.0 2.8 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.10 ETO23822.1 - 0.1 12.4 1.3 2.9 7.7 0.0 3.7 5 1 0 5 5 5 0 Kelch motif Kelch_1 PF01344.20 ETO23822.1 - 0.17 11.4 1.7 0.31 10.6 0.0 2.3 3 0 0 3 3 3 0 Kelch motif NdhM PF10664.4 ETO23823.1 - 0.0092 15.8 0.2 0.011 15.5 0.2 1.2 1 0 0 1 1 1 1 Cyanobacterial and plastid NDH-1 subunit M DUF45 PF01863.12 ETO23823.1 - 0.027 14.2 4.4 0.029 14.1 3.1 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF45 DUF4446 PF14584.1 ETO23823.1 - 0.028 14.2 1.3 0.03 14.1 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) VIT1 PF01988.14 ETO23823.1 - 0.034 13.6 2.3 0.041 13.3 1.6 1.1 1 0 0 1 1 1 0 VIT family Spore_YhaL PF14147.1 ETO23823.1 - 0.043 13.2 4.4 0.079 12.4 3.0 1.5 1 0 0 1 1 1 0 Sporulation protein YhaL Nbs1_C PF08599.5 ETO23823.1 - 0.19 11.6 1.9 0.39 10.6 0.9 2.0 1 1 1 2 2 2 0 DNA damage repair protein Nbs1 YgaB PF14182.1 ETO23823.1 - 0.46 10.7 10.8 0.6 10.3 7.5 1.1 1 0 0 1 1 1 0 YgaB-like protein Bap31 PF05529.7 ETO23823.1 - 0.82 9.0 4.6 0.96 8.8 3.2 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like zf-C4H2 PF10146.4 ETO23823.1 - 1.1 9.2 12.2 1.3 8.9 8.5 1.0 1 0 0 1 1 1 0 Zinc finger-containing protein HPPK PF01288.15 ETO23823.1 - 1.4 8.7 4.1 3.5 7.3 2.9 1.7 1 1 0 1 1 1 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) V_ATPase_I PF01496.14 ETO23823.1 - 1.8 6.3 7.6 2 6.1 5.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 ETO23823.1 - 4.2 6.9 7.2 4.9 6.7 5.0 1.1 1 0 0 1 1 1 0 IncA protein WD40 PF00400.27 ETO23824.1 - 7e-54 177.9 14.9 4.5e-11 42.1 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO23824.1 - 1.3e-11 44.5 0.3 7.6e-06 25.7 0.0 3.5 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 ETO23824.1 - 1.1e-06 27.9 0.6 0.23 10.5 0.0 4.3 1 1 2 3 3 3 3 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 ETO23824.1 - 2.2e-06 26.7 9.3 0.011 14.5 0.8 3.6 2 1 2 4 4 4 3 Nup133 N terminal like PQQ_2 PF13360.1 ETO23824.1 - 3.5e-06 26.6 0.4 9.2e-06 25.2 0.2 1.8 1 1 0 1 1 1 1 PQQ-like domain Nup160 PF11715.3 ETO23824.1 - 7.9e-06 24.2 1.5 1 7.3 0.1 4.0 2 2 2 4 4 4 3 Nucleoporin Nup120/160 Str_synth PF03088.11 ETO23824.1 - 2.8e-05 24.0 0.3 0.95 9.5 0.0 4.5 3 3 2 6 6 6 2 Strictosidine synthase PD40 PF07676.7 ETO23824.1 - 6e-05 22.6 4.0 3.7 7.3 0.0 5.5 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO23824.1 - 8.6e-05 20.9 0.6 0.25 9.5 0.1 2.8 2 1 1 3 3 3 2 Cytochrome D1 heme domain Me-amine-dh_H PF06433.6 ETO23824.1 - 0.001 17.8 0.0 0.054 12.1 0.0 2.9 2 1 1 3 3 3 1 Methylamine dehydrogenase heavy chain (MADH) SGL PF08450.7 ETO23824.1 - 0.0012 18.2 0.7 0.11 11.8 0.3 3.3 1 1 1 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region DUF3732 PF12532.3 ETO23824.1 - 0.022 14.2 0.2 0.99 8.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3732) Proteasome_A_N PF10584.4 ETO23824.1 - 0.058 12.7 11.9 2.4 7.5 0.0 5.3 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature TFIIIC_delta PF12657.2 ETO23824.1 - 0.072 12.7 1.5 1.2 8.7 0.0 3.0 3 1 0 3 3 3 0 Transcription factor IIIC subunit delta N-term DHFR_2 PF06442.6 ETO23824.1 - 0.13 11.9 0.0 2.1 8.0 0.0 2.6 3 1 0 3 3 3 0 R67 dihydrofolate reductase UPF0118 PF01594.11 ETO23825.1 - 0.021 13.8 0.2 0.021 13.8 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function DUF20 DUF912 PF06024.7 ETO23825.1 - 0.1 12.6 0.2 0.29 11.2 0.1 1.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) BTB PF00651.26 ETO23826.1 - 6.9e-21 74.3 0.6 1.1e-18 67.2 0.1 2.4 2 0 0 2 2 2 2 BTB/POZ domain BACK PF07707.10 ETO23826.1 - 0.33 10.8 5.0 0.68 9.8 0.4 2.6 3 0 0 3 3 3 0 BTB And C-terminal Kelch BRCT PF00533.21 ETO23827.1 - 1.5e-11 44.2 0.2 2.7e-06 27.4 0.0 2.3 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain zf-C3HC4_2 PF13923.1 ETO23831.1 - 9.4e-05 22.3 10.9 0.0012 18.7 8.2 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO23831.1 - 0.0001 21.9 5.1 0.00028 20.4 3.5 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO23831.1 - 0.0039 16.8 14.6 0.026 14.2 10.2 2.4 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 ETO23831.1 - 0.0047 16.6 5.7 0.0047 16.6 3.9 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.20 ETO23831.1 - 0.0074 15.9 12.4 0.0074 15.9 8.6 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO23831.1 - 0.064 13.0 15.0 0.15 11.8 9.9 2.1 1 1 0 1 1 1 0 Ring finger domain DUF3439 PF11921.3 ETO23831.1 - 0.49 10.1 23.4 2.2 8.0 5.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 ETO23831.1 - 0.64 7.6 20.9 0.96 7.1 1.6 2.2 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein zf-RING_6 PF14835.1 ETO23831.1 - 1.5 8.6 10.4 3.4 7.5 4.2 2.7 2 1 0 2 2 2 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 ETO23831.1 - 2.2 8.2 16.3 0.048 13.5 6.1 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Mucin PF01456.12 ETO23831.1 - 10 5.9 35.2 5.1 6.8 10.9 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein Borrelia_P83 PF05262.6 ETO23832.1 - 0.072 11.3 8.0 0.066 11.4 4.6 1.5 2 0 0 2 2 2 0 Borrelia P83/100 protein DOR PF14839.1 ETO23832.1 - 0.22 11.2 9.5 0.41 10.3 6.6 1.4 1 0 0 1 1 1 0 DOR family DUF501 PF04417.7 ETO23832.1 - 0.98 9.2 5.5 2.1 8.1 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF501) DUF106 PF01956.11 ETO23832.1 - 4.7 6.7 15.2 0.48 9.9 7.2 1.8 2 0 0 2 2 2 0 Integral membrane protein DUF106 DUF4606 PF15379.1 ETO23832.1 - 5.8 7.0 13.8 0.73 9.9 4.7 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4606) CAP_GLY PF01302.20 ETO23833.1 - 3.5e-35 119.5 8.3 1.1e-18 66.7 0.2 3.4 3 0 0 3 3 3 3 CAP-Gly domain DUF2296 PF10058.4 ETO23833.1 - 0.067 12.9 1.7 0.16 11.7 0.2 2.2 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) DnaJ_CXXCXGXG PF00684.14 ETO23833.1 - 0.08 13.0 5.0 0.24 11.4 2.9 2.2 1 1 1 2 2 2 0 DnaJ central domain DUF1272 PF06906.6 ETO23833.1 - 0.35 10.7 0.1 0.35 10.7 0.0 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1272) Zn_Tnp_IS1595 PF12760.2 ETO23833.1 - 1 9.2 10.6 0.25 11.1 1.7 2.8 2 1 1 3 3 3 0 Transposase zinc-ribbon domain zf-NADH-PPase PF09297.6 ETO23833.1 - 1.5 8.4 12.2 1.4 8.5 0.3 4.1 3 1 1 4 4 4 0 NADH pyrophosphatase zinc ribbon domain DUF106 PF01956.11 ETO23834.1 - 4.7e-30 104.3 0.3 4.7e-30 104.3 0.2 1.9 2 0 0 2 2 2 1 Integral membrane protein DUF106 DrsE_2 PF13686.1 ETO23834.1 - 0.031 14.0 0.0 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 DsrE/DsrF/DrsH-like family EF-hand_6 PF13405.1 ETO23835.1 - 3.6e-08 32.6 6.8 5.8e-05 22.6 0.2 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 ETO23835.1 - 2e-07 29.7 8.8 0.00016 20.7 0.3 4.1 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 ETO23835.1 - 6.6e-06 25.6 4.8 0.02 14.5 0.2 2.9 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_7 PF13499.1 ETO23835.1 - 3.3e-05 23.9 6.1 0.034 14.2 0.3 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 ETO23835.1 - 5e-05 22.4 7.2 0.0027 16.9 0.1 3.3 3 0 0 3 3 3 2 EF hand DUF600 PF04634.7 ETO23835.1 - 0.0014 18.6 2.9 0.15 12.1 0.7 2.1 1 1 1 2 2 2 2 Protein of unknown function, DUF600 DUF658 PF04936.7 ETO23835.1 - 0.0034 17.2 0.9 0.025 14.4 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF658) Toprim PF01751.17 ETO23835.1 - 0.017 15.0 0.5 0.11 12.5 0.4 2.0 1 1 0 1 1 1 0 Toprim domain Caleosin PF05042.8 ETO23835.1 - 0.062 12.8 0.1 2.2 7.8 0.0 2.2 2 0 0 2 2 2 0 Caleosin related protein SPARC_Ca_bdg PF10591.4 ETO23835.1 - 0.07 13.1 2.5 3.7 7.5 0.1 2.2 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF4255 PF14065.1 ETO23835.1 - 0.13 11.7 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4255) DUF1187 PF06688.6 ETO23835.1 - 0.13 12.4 0.5 0.77 9.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1187) DUF2341 PF10102.4 ETO23835.1 - 0.28 11.3 1.9 2.8 8.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2341) EF-hand_7 PF13499.1 ETO23836.1 - 9.8e-05 22.4 3.3 0.013 15.6 0.5 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO23836.1 - 0.0015 18.2 1.5 0.36 10.8 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 ETO23836.1 - 0.011 15.3 1.1 0.083 12.5 0.3 2.5 2 0 0 2 2 2 0 EF-hand domain pair Rapamycin_bind PF08771.6 ETO23836.1 - 0.054 13.5 0.1 0.091 12.8 0.1 1.5 1 0 0 1 1 1 0 Rapamycin binding domain DUF2088 PF09861.4 ETO23836.1 - 0.073 12.0 0.0 0.088 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2088) EF-hand_1 PF00036.27 ETO23836.1 - 0.13 11.6 2.9 0.83 9.1 0.4 2.6 2 0 0 2 2 2 0 EF hand RSS_P20 PF11757.3 ETO23837.1 - 0.75 9.9 8.8 0.06 13.4 0.4 2.9 2 2 1 3 3 3 0 Suppressor of RNA silencing P21-like 5-FTHF_cyc-lig PF01812.15 ETO23838.1 - 5.6e-34 117.5 0.0 5.8e-33 114.2 0.0 1.9 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Choline_transpo PF04515.7 ETO23840.1 - 7.9e-41 139.8 24.3 7.9e-41 139.8 16.8 3.8 2 2 0 2 2 2 1 Plasma-membrane choline transporter DUF3595 PF12166.3 ETO23842.1 - 0.01 14.7 0.6 0.011 14.6 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3595) Dicty_REP PF05086.7 ETO23842.1 - 0.062 11.0 1.5 0.073 10.8 1.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 ETO23842.1 - 0.12 12.1 4.5 0.24 11.1 3.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 ETO23842.1 - 0.32 8.9 5.9 0.51 8.2 4.1 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Gly-rich_Ago1 PF12764.2 ETO23842.1 - 2.3 8.8 5.1 1.2 9.8 1.4 1.9 2 0 0 2 2 2 0 Glycine-rich region of argonaut SP_C-Propep PF08999.5 ETO23843.1 - 0.016 14.7 3.3 0.031 13.7 2.3 1.5 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF2142 PF09913.4 ETO23843.1 - 0.063 11.9 0.8 0.15 10.6 0.6 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) Wzy_C PF04932.10 ETO23843.1 - 0.15 11.8 0.7 0.49 10.1 0.4 2.0 2 0 0 2 2 2 0 O-Antigen ligase O-antigen_lig PF13425.1 ETO23843.1 - 0.16 11.9 0.4 0.33 10.9 0.3 1.4 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Tetraspannin PF00335.15 ETO23843.1 - 0.56 9.4 9.1 3.4 6.8 0.1 2.7 2 0 0 2 2 2 0 Tetraspanin family MFS_Mycoplasma PF07672.8 ETO23843.1 - 6 5.9 12.4 0.11 11.6 0.6 2.9 3 0 0 3 3 3 0 Mycoplasma MFS transporter Pkinase PF00069.20 ETO23844.1 - 7.2e-07 28.6 0.2 1.1e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO23844.1 - 0.0058 15.7 0.2 0.0081 15.2 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DDE_Tnp_IS66_C PF13817.1 ETO23845.1 - 0.16 12.0 0.4 0.91 9.5 0.0 2.4 2 0 0 2 2 2 0 IS66 C-terminal element UPF0184 PF03670.8 ETO23846.1 - 0.88 9.7 6.5 0.16 12.1 0.4 2.8 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0184) DEAD PF00270.24 ETO23847.1 - 3.7e-08 33.0 0.1 5e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 ETO23847.1 - 1.8e-05 24.9 0.0 3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 ETO23847.1 - 0.0033 17.2 0.0 0.0047 16.6 0.0 1.3 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.10 ETO23847.1 - 0.02 14.7 0.0 5.7 6.7 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2075 PF09848.4 ETO23847.1 - 0.077 11.9 0.0 0.095 11.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Nucleoplasmin PF03066.10 ETO23848.1 - 0.0017 17.8 0.9 0.0017 17.8 0.6 2.3 2 0 0 2 2 2 1 Nucleoplasmin Daxx PF03344.10 ETO23848.1 - 4.5 5.6 32.8 0.47 8.8 10.1 2.1 2 0 0 2 2 2 0 Daxx Family DIX PF00778.12 ETO23849.1 - 0.0086 15.7 0.0 0.54 10.0 0.0 2.3 2 0 0 2 2 2 1 DIX domain DUF1264 PF06884.6 ETO23849.1 - 0.021 14.3 0.0 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1264) DUF2644 PF10841.3 ETO23849.1 - 0.12 12.4 0.0 2.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2644) HBS1_N PF08938.5 ETO23849.1 - 1.8 8.7 5.6 1.6 8.9 0.1 3.2 3 1 1 4 4 4 0 HBS1 N-terminus Med15 PF09606.5 ETO23850.1 - 0.011 14.0 86.6 0.096 10.8 2.6 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Tetraspannin PF00335.15 ETO23851.1 - 0.00083 18.6 5.1 0.0086 15.3 3.5 2.4 1 1 0 1 1 1 1 Tetraspanin family TMEM154 PF15102.1 ETO23851.1 - 0.009 15.7 9.0 0.009 15.7 6.2 3.5 3 3 1 4 4 4 1 TMEM154 protein family Podoplanin PF05808.6 ETO23851.1 - 0.013 15.0 4.5 0.013 15.0 3.1 2.9 2 1 0 2 2 2 0 Podoplanin OCD_Mu_crystall PF02423.10 ETO23853.1 - 4.7e-05 22.3 0.0 7e-05 21.7 0.0 1.3 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family RRM_1 PF00076.17 ETO23856.1 - 5.4e-16 57.9 0.1 8.9e-09 34.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO23856.1 - 2.3e-12 46.6 0.1 3.5e-07 30.0 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO23856.1 - 2.2e-11 43.4 0.0 2.8e-06 27.0 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 ETO23856.1 - 0.033 13.9 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 DUF4318 PF14201.1 ETO23856.1 - 0.11 12.3 0.2 0.26 11.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4318) EF-hand_6 PF13405.1 ETO23857.1 - 7.9e-05 22.2 0.0 0.19 11.7 0.0 2.9 2 1 1 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 ETO23857.1 - 0.00058 19.4 0.4 1.8 8.2 0.0 3.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 ETO23857.1 - 0.0077 15.4 0.0 1.6 8.2 0.0 2.6 2 1 1 3 3 3 2 EF hand EF-hand_7 PF13499.1 ETO23857.1 - 0.013 15.6 0.0 0.042 13.9 0.0 1.9 1 1 0 1 1 1 0 EF-hand domain pair NA37 PF04245.8 ETO23857.1 - 0.029 13.7 0.5 0.038 13.3 0.1 1.4 2 0 0 2 2 2 0 37-kD nucleoid-associated bacterial protein WD40 PF00400.27 ETO23858.1 - 6e-74 241.5 10.6 3.2e-14 52.1 0.1 7.0 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO23858.1 - 6.4e-07 27.8 5.9 0.0033 15.6 0.1 4.5 2 2 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO23858.1 - 7.6e-05 21.6 5.0 0.53 8.9 0.0 3.2 1 1 0 2 2 2 2 Nup133 N terminal like DUF1258 PF06869.7 ETO23858.1 - 0.0001 21.5 3.8 0.26 10.3 0.0 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF1258) PQQ_2 PF13360.1 ETO23858.1 - 0.00076 19.0 0.2 0.64 9.4 0.1 2.5 1 1 1 2 2 2 2 PQQ-like domain Cytochrom_D1 PF02239.11 ETO23858.1 - 0.0027 16.0 0.5 3.5 5.8 0.0 3.1 1 1 3 4 4 4 2 Cytochrome D1 heme domain Formyl_trans_C PF02911.13 ETO23858.1 - 0.041 13.9 0.0 5.7 7.0 0.0 3.1 1 1 1 3 3 3 0 Formyl transferase, C-terminal domain DUF3601 PF12208.3 ETO23858.1 - 0.046 13.6 0.0 8.4 6.4 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3601) Ribosomal_L21e PF01157.13 ETO23858.1 - 0.065 13.0 0.3 4.5 7.1 0.0 2.8 2 2 1 3 3 3 0 Ribosomal protein L21e Vac_Fusion PF02346.11 ETO23858.1 - 0.12 11.7 0.3 2.4 7.6 0.1 2.9 2 1 1 3 3 3 0 Chordopoxvirus fusion protein PD40 PF07676.7 ETO23858.1 - 0.69 9.6 3.2 15 5.3 0.0 4.2 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat MMR_HSR1 PF01926.18 ETO23859.1 - 8.2e-08 32.2 0.5 1.2e-07 31.7 0.3 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 ETO23859.1 - 6.2e-06 26.7 0.7 8.8e-06 26.2 0.5 1.3 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 ETO23859.1 - 5.6e-05 22.3 0.4 7e-05 22.0 0.3 1.1 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 ETO23859.1 - 0.00036 19.7 0.3 0.0006 19.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 ETO23859.1 - 0.01 16.1 0.8 0.013 15.7 0.6 1.3 1 1 0 1 1 1 1 ABC transporter DUF87 PF01935.12 ETO23859.1 - 0.011 15.6 1.5 0.26 11.0 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 MOR2-PAG1_C PF14225.1 ETO23860.1 - 6.8e-10 39.1 0.8 5.7e-09 36.0 0.2 2.4 3 0 0 3 3 3 1 Cell morphogenesis C-terminal TRAP_alpha PF03896.11 ETO23861.1 - 9.2e-07 28.1 2.0 1e-06 27.9 1.4 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF1510 PF07423.6 ETO23861.1 - 0.0002 20.8 1.7 0.00022 20.6 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) FAM176 PF14851.1 ETO23861.1 - 0.011 15.4 6.7 0.024 14.3 4.6 1.6 1 1 0 1 1 1 0 FAM176 family SpoIIIAH PF12685.2 ETO23861.1 - 0.016 14.7 0.0 0.019 14.4 0.0 1.0 1 0 0 1 1 1 0 SpoIIIAH-like protein Tetraspannin PF00335.15 ETO23861.1 - 0.027 13.7 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Tetraspanin family TRAM_LAG1_CLN8 PF03798.11 ETO23861.1 - 0.74 9.3 4.9 1.2 8.6 0.5 2.0 2 0 0 2 2 2 0 TLC domain Neur_chan_memb PF02932.11 ETO23861.1 - 4.8 7.0 5.9 0.54 10.1 0.6 1.9 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Thioredoxin_3 PF13192.1 ETO23864.1 - 0.0088 15.8 0.1 0.021 14.6 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin domain WD40 PF00400.27 ETO23864.1 - 0.026 14.3 9.4 0.12 12.2 0.3 4.3 6 0 0 6 6 6 0 WD domain, G-beta repeat Secretin_N_2 PF07655.8 ETO23864.1 - 0.041 14.2 11.2 0.16 12.3 7.8 2.0 1 0 0 1 1 1 0 Secretin N-terminal domain ZZ PF00569.12 ETO23865.1 - 6.1e-08 32.0 22.2 3.6e-05 23.2 1.7 4.9 5 0 0 5 5 5 2 Zinc finger, ZZ type zf-Di19 PF05605.7 ETO23865.1 - 9e-05 22.5 2.2 9e-05 22.5 1.5 3.2 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding Adaptin_binding PF10199.4 ETO23865.1 - 0.0034 17.6 14.9 0.11 12.7 5.0 2.5 2 0 0 2 2 2 2 Alpha and gamma adaptin binding protein p34 CDC45 PF02724.9 ETO23865.1 - 0.28 9.1 16.5 0.068 11.1 2.1 2.1 2 0 0 2 2 2 0 CDC45-like protein NARP1 PF12569.3 ETO23865.1 - 5.8 5.5 19.6 0.009 14.8 3.0 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 MMPL PF03176.10 ETO23866.1 - 4.1e-26 91.4 10.8 1.1e-24 86.8 9.2 2.0 2 1 0 2 2 2 1 MMPL family ABC2_membrane_5 PF13346.1 ETO23866.1 - 8 5.6 13.9 5.4 6.2 1.7 3.1 2 1 1 3 3 3 0 ABC-2 family transporter protein DUF2457 PF10446.4 ETO23867.1 - 0.00082 18.2 9.7 0.0011 17.8 6.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) TRP PF06011.7 ETO23867.1 - 0.0028 16.3 0.0 0.0042 15.7 0.0 1.3 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel DUF1510 PF07423.6 ETO23867.1 - 0.003 16.9 1.8 0.0038 16.6 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) FAM176 PF14851.1 ETO23867.1 - 0.0042 16.7 0.1 0.0068 16.1 0.1 1.3 1 0 0 1 1 1 1 FAM176 family TRAP_alpha PF03896.11 ETO23867.1 - 0.022 13.7 0.5 0.035 13.0 0.4 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Herpes_gE PF02480.11 ETO23867.1 - 0.029 12.6 0.1 0.042 12.1 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E S-antigen PF05756.6 ETO23867.1 - 0.95 9.4 10.3 2.3 8.2 7.2 1.7 1 0 0 1 1 1 0 S-antigen protein RXT2_N PF08595.6 ETO23867.1 - 1.4 8.7 8.9 2.4 7.9 6.1 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal TLD PF07534.11 ETO23868.1 - 2.9e-13 49.9 0.0 6.1e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 TLD DUF1664 PF07889.7 ETO23868.1 - 0.4 10.4 12.2 29 4.4 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Nup54 PF13874.1 ETO23868.1 - 3.1 7.4 10.1 7.3 6.2 6.5 2.0 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Fib_alpha PF08702.5 ETO23868.1 - 5.1 7.2 14.1 1.3 9.1 6.7 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ORF6C PF10552.4 ETO23868.1 - 6.7 6.4 12.8 3 7.5 3.6 2.9 2 1 1 3 3 3 0 ORF6C domain WWE PF02825.15 ETO23870.1 - 0.046 13.1 0.3 0.23 10.9 0.2 2.1 1 1 0 1 1 1 0 WWE domain Peptidase_C65 PF10275.4 ETO23871.1 - 6.3e-22 78.1 0.3 9.6e-22 77.5 0.2 1.2 1 0 0 1 1 1 1 Peptidase C65 Otubain Merozoite_SPAM PF07133.6 ETO23871.1 - 0.012 15.4 9.4 0.015 15.1 6.5 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) OTU PF02338.14 ETO23871.1 - 0.015 15.8 0.3 0.033 14.7 0.0 1.8 2 1 0 2 2 2 0 OTU-like cysteine protease priB_priC PF07445.7 ETO23871.1 - 0.017 14.5 0.9 0.026 13.9 0.6 1.4 1 0 0 1 1 1 0 Primosomal replication protein priB and priC Presenilin PF01080.12 ETO23872.1 - 8.1e-06 24.9 18.8 8.1e-06 24.9 13.0 2.9 3 0 0 3 3 3 2 Presenilin BUD22 PF09073.5 ETO23873.1 - 0.0022 17.1 19.6 0.0038 16.3 13.6 1.4 1 0 0 1 1 1 1 BUD22 DUF2890 PF11081.3 ETO23873.1 - 0.012 15.6 21.3 0.02 14.9 14.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF1664 PF07889.7 ETO23873.1 - 0.079 12.7 1.1 0.14 11.9 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) IncA PF04156.9 ETO23873.1 - 0.24 10.9 12.7 0.22 11.1 2.4 2.1 2 0 0 2 2 2 0 IncA protein Lin-8 PF03353.10 ETO23873.1 - 0.4 9.9 21.6 0.62 9.2 15.0 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF2457 PF10446.4 ETO23873.1 - 0.4 9.3 23.8 0.65 8.6 16.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 ETO23873.1 - 0.47 8.8 23.0 0.83 8.0 15.9 1.4 1 0 0 1 1 1 0 Daxx Family DUF3450 PF11932.3 ETO23873.1 - 3.7 6.7 11.8 0.15 11.2 4.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Pkinase PF00069.20 ETO23874.1 - 2.6e-39 134.9 0.4 2.6e-39 134.9 0.3 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO23874.1 - 6.4e-30 104.0 0.3 1.3e-29 103.0 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1589 PF07628.6 ETO23874.1 - 0.007 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1589) Kinase-like PF14531.1 ETO23874.1 - 0.0085 15.0 0.0 0.015 14.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like YqgF PF14639.1 ETO23874.1 - 0.029 13.9 0.0 0.077 12.5 0.0 1.7 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 Kdo PF06293.9 ETO23874.1 - 0.049 12.7 0.0 0.095 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO23874.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 ETO23874.1 - 0.12 11.6 0.0 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 RIO1 family FliD_N PF02465.13 ETO23875.1 - 5.2 7.4 12.1 0.94 9.8 3.1 2.4 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF4041 PF13250.1 ETO23876.1 - 0.011 15.2 0.4 0.026 14.0 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4041) DUF3391 PF11871.3 ETO23876.1 - 0.048 13.8 3.2 0.12 12.6 1.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) DUF948 PF06103.6 ETO23876.1 - 0.052 13.4 0.8 0.097 12.5 0.6 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) BofC_C PF08955.5 ETO23876.1 - 0.079 13.0 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 BofC C-terminal domain Glyco_hydro_31 PF01055.21 ETO23876.1 - 0.087 11.6 0.1 0.096 11.4 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 Peptidase_S46 PF10459.4 ETO23876.1 - 1.6 7.0 7.3 1.8 6.9 5.1 1.0 1 0 0 1 1 1 0 Peptidase S46 YqzH PF14164.1 ETO23876.1 - 1.9 8.4 8.1 2.2 8.2 1.3 2.9 2 2 0 2 2 2 0 YqzH-like protein Rad60-SLD PF11976.3 ETO23877.1 - 4.4e-09 35.9 0.0 7.2e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 ETO23877.1 - 1.1e-08 34.2 0.0 1.9e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family zinc_ribbon_5 PF13719.1 ETO23877.1 - 0.013 15.0 0.6 0.058 12.9 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 ETO23877.1 - 0.014 15.0 0.6 0.064 12.9 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain CTV_P23 PF04808.7 ETO23879.1 - 0.13 11.6 2.3 0.32 10.2 1.4 1.8 2 0 0 2 2 2 0 Citrus tristeza virus (CTV) P23 protein rve_3 PF13683.1 ETO23879.1 - 0.19 11.2 1.6 0.43 10.1 1.1 1.6 1 0 0 1 1 1 0 Integrase core domain RNA_pol PF00940.14 ETO23880.1 - 3.5e-85 285.9 0.0 4e-85 285.7 0.0 1.0 1 0 0 1 1 1 1 DNA-dependent RNA polymerase TFIIA PF03153.8 ETO23881.1 - 0.085 12.7 17.4 0.15 11.9 12.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nucleoplasmin PF03066.10 ETO23881.1 - 1.6 8.2 12.8 1.5 8.3 7.6 1.9 2 0 0 2 2 2 0 Nucleoplasmin Prog_receptor PF02161.10 ETO23881.1 - 2.4 6.8 5.7 4.5 5.9 4.0 1.3 1 0 0 1 1 1 0 Progesterone receptor Mucin PF01456.12 ETO23882.1 - 0.1 12.3 10.1 0.2 11.4 7.0 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Macoilin PF09726.4 ETO23882.1 - 0.11 10.7 28.2 0.13 10.5 19.6 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF2968 PF11180.3 ETO23882.1 - 1.9 7.8 9.1 5.1 6.4 5.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) SSP160 PF06933.6 ETO23882.1 - 9.6 4.0 17.2 13 3.5 11.9 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Aldo_ket_red PF00248.16 ETO23883.1 - 1.4e-26 92.9 0.0 2.6e-26 92.0 0.0 1.4 2 0 0 2 2 2 1 Aldo/keto reductase family Exonuc_VII_S PF02609.11 ETO23883.1 - 0.25 11.1 1.4 17 5.2 0.1 2.4 2 0 0 2 2 2 0 Exonuclease VII small subunit Methyltransf_26 PF13659.1 ETO23884.1 - 7.2e-13 48.5 0.0 1.1e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO23884.1 - 4.9e-10 39.1 0.0 9e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETO23884.1 - 3.5e-09 36.2 0.0 7.5e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 ETO23884.1 - 1.7e-08 35.0 0.0 3.7e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO23884.1 - 8.7e-05 22.9 0.0 0.00026 21.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETO23884.1 - 0.00011 22.4 0.0 0.00027 21.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 ETO23884.1 - 0.00029 19.9 0.0 0.041 12.9 0.0 2.1 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.7 ETO23884.1 - 0.00031 21.1 0.0 0.00072 20.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 ETO23884.1 - 0.00077 18.6 0.0 0.0017 17.5 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 ETO23884.1 - 0.00079 19.0 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_16 PF10294.4 ETO23884.1 - 0.0017 17.8 0.0 0.0039 16.6 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_4 PF02390.12 ETO23884.1 - 0.0041 16.1 0.0 0.0093 15.0 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Eco57I PF07669.6 ETO23884.1 - 0.0093 16.3 0.0 0.14 12.5 0.0 2.4 2 0 0 2 2 2 1 Eco57I restriction-modification methylase N6_Mtase PF02384.11 ETO23884.1 - 0.012 14.7 0.0 0.026 13.6 0.0 1.6 2 0 0 2 2 2 0 N-6 DNA Methylase Cons_hypoth95 PF03602.10 ETO23884.1 - 0.053 12.8 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 AdoMet_MTase PF07757.8 ETO23884.1 - 0.067 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase PCMT PF01135.14 ETO23884.1 - 0.071 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_3 PF01596.12 ETO23884.1 - 0.14 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase zf-RING_2 PF13639.1 ETO23885.1 - 1.1e-09 37.9 14.1 1.1e-09 37.9 9.8 3.4 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 ETO23885.1 - 4e-05 23.1 15.1 4e-05 23.1 10.4 3.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO23885.1 - 0.00085 19.2 14.4 0.00085 19.2 10.0 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO23885.1 - 0.0092 15.6 14.4 0.0092 15.6 10.0 3.3 2 1 0 2 2 2 1 zinc-RING finger domain Pap_E4 PF02711.9 ETO23885.1 - 10 7.0 6.7 3 8.7 1.7 2.5 2 0 0 2 2 2 0 E4 protein DUF2615 PF11027.3 ETO23886.1 - 0.074 12.9 0.3 0.28 11.1 0.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2615) MazG-like PF12643.2 ETO23887.1 - 0.025 14.5 4.9 0.036 14.0 0.2 2.8 2 1 0 2 2 2 0 MazG-like family RNA_polI_A14 PF08203.6 ETO23887.1 - 0.043 14.0 1.2 0.11 12.7 0.0 2.3 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 HTH_32 PF13565.1 ETO23887.1 - 0.63 10.8 5.8 0.2 12.4 0.8 2.6 3 0 0 3 3 3 0 Homeodomain-like domain Pkinase PF00069.20 ETO23888.1 - 2.4e-18 66.2 0.0 4.1e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO23888.1 - 0.00029 20.0 0.1 0.00057 19.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 ETO23888.1 - 0.011 15.4 1.0 0.014 15.1 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 ETO23888.1 - 0.056 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETO23888.1 - 0.083 11.8 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like SOXp PF12336.3 ETO23888.1 - 0.32 11.6 2.8 0.65 10.6 2.0 1.5 1 0 0 1 1 1 0 SOX transcription factor Filament PF00038.16 ETO23889.1 - 0.0011 18.5 3.2 0.0015 18.0 2.2 1.2 1 0 0 1 1 1 1 Intermediate filament protein DUF3450 PF11932.3 ETO23889.1 - 0.026 13.8 5.6 0.042 13.1 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) IncA PF04156.9 ETO23889.1 - 1.8 8.1 10.1 2.9 7.4 7.0 1.3 1 0 0 1 1 1 0 IncA protein DUF1980 PF09323.5 ETO23889.1 - 6.6 6.4 13.3 3.3 7.4 0.9 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) Pterin_bind PF00809.17 ETO23890.1 - 3.4e-42 144.2 0.0 7.1e-42 143.1 0.0 1.6 1 0 0 1 1 1 1 Pterin binding enzyme TPR_2 PF07719.12 ETO23891.1 - 6.8e-05 22.4 0.1 0.019 14.8 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO23891.1 - 0.00071 19.1 0.1 0.23 11.1 0.0 2.5 2 0 0 2 2 2 2 TPR repeat SHNi-TPR PF10516.4 ETO23891.1 - 0.0033 16.6 0.0 0.0066 15.6 0.0 1.5 1 0 0 1 1 1 1 SHNi-TPR TPR_8 PF13181.1 ETO23891.1 - 0.016 14.9 0.1 3.3 7.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETO23891.1 - 0.042 13.7 0.5 2 8.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETO23891.1 - 0.12 13.0 0.7 2.7 8.8 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.27 ETO23892.1 - 4.8e-39 130.8 23.3 6.4e-08 32.1 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Antig_Caf1 PF09255.5 ETO23892.1 - 0.00094 19.0 0.3 0.003 17.4 0.1 1.9 2 0 0 2 2 2 1 Caf1 Capsule antigen GAS PF13851.1 ETO23893.1 - 0.0031 16.7 20.5 0.0031 16.7 14.2 3.6 2 1 0 3 3 3 1 Growth-arrest specific micro-tubule binding COG2 PF06148.6 ETO23893.1 - 2 8.2 20.0 0.031 14.1 5.2 3.1 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.7 ETO23893.1 - 7.4 6.3 18.1 2.4 7.9 0.5 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF2956 PF11169.3 ETO23894.1 - 0.03 14.2 6.6 0.03 14.2 4.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2956) MIP-T3 PF10243.4 ETO23894.1 - 0.13 10.6 29.6 0.16 10.4 20.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 APC_CDC26 PF10471.4 ETO23894.1 - 1.6 9.5 26.8 0.17 12.6 10.6 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Apis_Csd PF11671.3 ETO23894.1 - 2 8.2 26.4 2.5 7.8 11.0 2.2 2 0 0 2 2 2 0 Complementary sex determiner protein DUF1675 PF07897.6 ETO23894.1 - 3.8 7.2 22.5 0.082 12.7 9.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1675) Dynamitin PF04912.9 ETO23895.1 - 1.5e-19 70.0 4.4 1.7e-19 69.9 3.1 1.0 1 0 0 1 1 1 1 Dynamitin Allexi_40kDa PF05549.6 ETO23895.1 - 0.24 10.6 4.2 0.18 11.0 0.3 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein RRM_6 PF14259.1 ETO23896.1 - 6.2e-08 32.5 0.9 2.1e-05 24.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO23896.1 - 2.4e-07 30.2 0.5 0.00019 20.9 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NS3_envE PF02723.9 ETO23896.1 - 0.014 15.2 2.2 0.035 14.0 1.5 1.6 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E DUF3753 PF12575.3 ETO23896.1 - 0.015 15.0 0.2 0.036 13.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) RRM_5 PF13893.1 ETO23896.1 - 0.033 14.0 0.2 4.4 7.2 0.0 2.6 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF912 PF06024.7 ETO23896.1 - 0.048 13.7 0.3 0.088 12.8 0.2 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SecY PF00344.15 ETO23896.1 - 0.07 12.0 0.1 0.092 11.6 0.1 1.2 1 0 0 1 1 1 0 SecY translocase DUF2431 PF10354.4 ETO23897.1 - 7.1e-20 71.6 3.1 1.2e-16 61.1 0.1 3.0 2 1 1 3 3 3 2 Domain of unknown function (DUF2431) zf-C2H2_6 PF13912.1 ETO23897.1 - 8.3e-05 22.3 23.0 0.0038 17.0 0.2 4.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 ETO23897.1 - 0.0038 17.4 2.4 0.0038 17.4 1.7 5.1 5 1 0 5 5 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 ETO23897.1 - 0.0054 17.0 27.4 0.61 10.5 0.1 5.2 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-met2 PF12907.2 ETO23897.1 - 0.0064 16.4 18.3 0.28 11.2 0.1 4.2 4 0 0 4 4 4 2 Zinc-binding zf-met PF12874.2 ETO23897.1 - 0.025 14.7 23.4 0.73 10.1 0.1 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 ETO23897.1 - 0.19 11.8 25.8 0.75 9.9 5.5 3.5 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Prok-RING_1 PF14446.1 ETO23897.1 - 0.26 11.0 11.1 6.4 6.5 0.1 4.2 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 PyrI_C PF02748.10 ETO23897.1 - 0.65 9.4 5.1 1.3 8.5 0.3 3.3 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_jaz PF12171.3 ETO23897.1 - 0.95 9.6 26.4 0.58 10.3 0.7 4.7 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding ADK_lid PF05191.9 ETO23897.1 - 2.9 7.6 6.4 3.9 7.2 0.0 3.1 3 0 0 3 3 3 0 Adenylate kinase, active site lid C1_4 PF07975.7 ETO23897.1 - 3.4 7.7 17.3 2.2 8.3 0.6 4.0 2 2 2 4 4 4 0 TFIIH C1-like domain RuBisCO_small PF00101.15 ETO23898.1 - 0.018 14.8 0.6 0.24 11.2 0.2 2.2 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase, small chain DUF2521 PF10730.4 ETO23898.1 - 0.13 12.0 1.3 0.16 11.8 0.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2521) Ribonuc_L-PSP PF01042.16 ETO23900.1 - 4.4e-39 132.9 0.1 5.7e-39 132.6 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Rab3-GTPase_cat PF13890.1 ETO23900.1 - 0.04 13.2 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit Ras PF00071.17 ETO23901.1 - 7.2e-41 139.2 1.5 9.4e-22 77.1 0.1 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 ETO23901.1 - 1.5e-10 41.6 0.9 1.4e-09 38.4 0.6 2.2 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO23901.1 - 0.00049 19.3 1.5 0.55 9.4 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family Adeno_E4 PF05385.6 ETO23901.1 - 0.0047 16.8 0.1 0.0078 16.1 0.0 1.4 1 0 0 1 1 1 1 Mastadenovirus early E4 13 kDa protein DUF258 PF03193.11 ETO23901.1 - 0.017 14.3 0.1 0.04 13.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Hpr_kinase_C PF07475.7 ETO23901.1 - 0.018 14.3 0.1 2.3 7.4 0.0 2.2 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_22 PF13401.1 ETO23901.1 - 0.027 14.6 0.1 0.075 13.1 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 ETO23901.1 - 0.035 14.0 0.0 0.083 12.8 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 ETO23901.1 - 0.054 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 ETO23901.1 - 0.056 13.0 0.0 0.77 9.4 0.0 2.6 2 1 0 2 2 2 0 NACHT domain MCM PF00493.18 ETO23901.1 - 0.06 12.1 0.2 0.75 8.5 0.0 2.1 2 0 0 2 2 2 0 MCM2/3/5 family GTP_EFTU PF00009.22 ETO23901.1 - 0.068 12.5 0.2 0.23 10.8 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF563 PF04577.9 ETO23902.1 - 4.2e-15 56.2 0.0 1.6e-11 44.5 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF563) zf-TRAF PF02176.13 ETO23903.1 - 0.00081 19.7 6.4 0.00089 19.5 2.1 2.8 1 1 1 2 2 2 1 TRAF-type zinc finger OmpH PF03938.9 ETO23903.1 - 0.0016 18.3 2.4 0.0016 18.3 1.7 1.9 1 1 1 2 2 2 1 Outer membrane protein (OmpH-like) RasGAP_C PF03836.10 ETO23903.1 - 0.03 14.0 2.4 0.03 14.0 1.7 2.6 3 0 0 3 3 3 0 RasGAP C-terminus zf-C3HC4_2 PF13923.1 ETO23903.1 - 0.034 14.1 1.1 0.4 10.7 0.3 3.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TMF_DNA_bd PF12329.3 ETO23903.1 - 0.042 13.6 2.4 0.042 13.6 1.6 2.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF641 PF04859.7 ETO23903.1 - 0.26 11.0 6.9 0.097 12.4 2.0 2.2 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) TcdB_N PF12918.2 ETO23903.1 - 0.35 10.9 5.3 0.2 11.7 1.4 2.4 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain IncA PF04156.9 ETO23903.1 - 1.8 8.1 12.8 4.4 6.8 8.9 1.6 1 1 0 1 1 1 0 IncA protein ADIP PF11559.3 ETO23903.1 - 2 8.2 19.1 0.039 13.8 3.4 3.1 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding HR1 PF02185.11 ETO23903.1 - 2.3 8.0 8.9 6.3 6.6 5.3 2.3 1 1 1 2 2 2 0 Hr1 repeat ATG16 PF08614.6 ETO23903.1 - 4.4 7.0 14.8 0.17 11.7 2.0 2.5 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF3246 PF11596.3 ETO23904.1 - 0.017 14.4 2.5 0.025 13.8 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) MMR_HSR1 PF01926.18 ETO23905.1 - 3.4e-06 26.9 1.6 4.3e-06 26.6 0.0 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 ETO23905.1 - 0.00089 19.5 0.0 0.00089 19.5 0.0 2.5 2 1 0 2 2 1 1 AAA domain Gtr1_RagA PF04670.7 ETO23905.1 - 0.0041 16.2 0.1 0.0041 16.2 0.1 2.6 2 2 0 2 2 1 1 Gtr1/RagA G protein conserved region AIG1 PF04548.11 ETO23905.1 - 0.0096 15.0 0.6 0.0096 15.0 0.4 2.9 2 1 0 2 2 1 1 AIG1 family AAA_17 PF13207.1 ETO23905.1 - 0.015 16.1 0.5 0.031 15.0 0.0 2.0 2 1 0 2 2 1 0 AAA domain AAA_29 PF13555.1 ETO23905.1 - 0.016 14.7 0.2 0.056 12.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.1 ETO23905.1 - 0.023 14.8 2.4 0.076 13.1 0.1 2.4 1 1 1 2 2 2 0 AAA domain SRP54 PF00448.17 ETO23905.1 - 0.024 14.0 0.2 0.024 14.0 0.1 2.4 2 1 0 2 2 1 0 SRP54-type protein, GTPase domain SapB_1 PF05184.10 ETO23905.1 - 0.037 13.8 0.4 0.085 12.7 0.3 1.6 1 0 0 1 1 1 0 Saposin-like type B, region 1 AAA_33 PF13671.1 ETO23905.1 - 0.047 13.5 0.0 0.16 11.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETO23905.1 - 0.14 12.0 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.1 ETO23905.1 - 0.16 11.5 0.0 0.16 11.5 0.0 2.8 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.22 ETO23905.1 - 0.34 11.2 5.1 0.23 11.7 0.1 2.3 1 1 1 2 2 2 0 ABC transporter ApoO PF09769.4 ETO23905.1 - 1.6 8.4 4.7 4.1 7.0 3.3 1.7 1 1 0 1 1 1 0 Apolipoprotein O Pox_Ag35 PF03286.9 ETO23905.1 - 2.8 7.4 25.2 18 4.8 16.5 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein tRNA_synt_1c_R2 PF04557.10 ETO23905.1 - 3.5 8.3 20.3 7.9 7.2 13.5 2.1 2 0 0 2 2 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 DUF3987 PF13148.1 ETO23905.1 - 5.1 5.5 13.2 16 3.9 8.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) G-alpha PF00503.15 ETO23905.1 - 7 5.2 19.0 4 6.0 11.6 1.8 2 1 0 2 2 2 0 G-protein alpha subunit DUF3464 PF11947.3 ETO23905.1 - 8.6 5.8 8.2 14 5.1 5.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) RAI1 PF08652.6 ETO23906.1 - 1.2 9.0 5.3 1.1 9.0 1.7 2.1 2 0 0 2 2 2 0 RAI1 like PD-(D/E)XK nuclease Pkinase PF00069.20 ETO23907.1 - 1.8e-25 89.5 0.2 3.4e-25 88.6 0.0 1.5 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO23907.1 - 6e-08 32.0 0.1 7.7e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO23907.1 - 0.0055 15.6 0.0 0.0066 15.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like IncA PF04156.9 ETO23908.1 - 0.00014 21.5 16.4 0.00071 19.2 5.0 2.9 2 0 0 2 2 2 2 IncA protein Dfp1_Him1_M PF08630.5 ETO23908.1 - 0.0012 18.6 0.5 0.0012 18.6 0.3 2.8 3 0 0 3 3 3 1 Dfp1/Him1, central region TBPIP PF07106.8 ETO23908.1 - 0.0021 17.6 7.1 0.0021 17.6 4.9 3.4 3 1 1 4 4 4 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Seryl_tRNA_N PF02403.17 ETO23908.1 - 0.0029 17.6 18.0 0.056 13.4 2.9 3.6 3 1 1 4 4 4 2 Seryl-tRNA synthetase N-terminal domain GOLGA2L5 PF15070.1 ETO23908.1 - 0.0053 15.3 5.0 0.0053 15.3 3.4 2.6 3 0 0 3 3 3 1 Putative golgin subfamily A member 2-like protein 5 Filament PF00038.16 ETO23908.1 - 0.006 16.1 2.5 0.006 16.1 1.8 2.7 2 0 0 2 2 2 1 Intermediate filament protein Lzipper-MIP1 PF14389.1 ETO23908.1 - 0.011 15.7 16.2 0.02 14.9 6.4 3.1 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DB PF01682.14 ETO23908.1 - 0.038 14.0 1.9 0.15 12.1 0.4 2.5 2 0 0 2 2 2 0 DB module APG6 PF04111.7 ETO23908.1 - 0.12 11.3 15.7 0.68 8.9 2.1 2.6 2 0 0 2 2 2 0 Autophagy protein Apg6 PspA_IM30 PF04012.7 ETO23908.1 - 0.2 10.9 16.6 0.14 11.4 4.4 2.5 2 0 0 2 2 2 0 PspA/IM30 family FlxA PF14282.1 ETO23908.1 - 0.31 11.0 25.1 0.038 13.9 2.9 4.2 3 1 1 4 4 4 0 FlxA-like protein DASH_Dad3 PF08656.5 ETO23908.1 - 0.52 10.0 12.2 0.68 9.6 0.2 4.9 5 0 0 5 5 5 0 DASH complex subunit Dad3 HR1 PF02185.11 ETO23908.1 - 0.56 9.9 22.1 1.3 8.8 2.1 5.2 4 1 1 5 5 5 0 Hr1 repeat Cep57_MT_bd PF06657.8 ETO23908.1 - 0.57 10.1 18.1 6.5 6.7 0.7 4.7 4 1 1 5 5 5 0 Centrosome microtubule-binding domain of Cep57 UBN2 PF14223.1 ETO23908.1 - 1.5 8.6 12.7 0.17 11.6 0.4 4.2 3 2 2 5 5 5 0 gag-polypeptide of LTR copia-type DUF1664 PF07889.7 ETO23908.1 - 1.6 8.5 12.4 7.7 6.3 2.6 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Mnd1 PF03962.10 ETO23908.1 - 1.9 8.1 23.8 0.021 14.5 2.0 3.3 4 0 0 4 4 3 0 Mnd1 family Vps51 PF08700.6 ETO23908.1 - 4 7.3 9.1 11 5.9 0.2 4.0 2 1 1 3 3 3 0 Vps51/Vps67 Ammonium_transp PF00909.16 ETO23911.1 - 3.3e-35 121.3 3.9 4.4e-35 120.9 2.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Ribosomal_S8e PF01201.17 ETO23912.1 - 3.6e-32 111.2 3.2 4.6e-32 110.9 2.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e 7tm_1 PF00001.16 ETO23913.1 - 0.02 14.0 1.4 0.053 12.6 1.0 1.8 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) GRP PF07172.6 ETO23913.1 - 0.038 14.4 0.6 0.038 14.4 0.4 2.3 2 1 0 2 2 2 0 Glycine rich protein family FAM209 PF15206.1 ETO23913.1 - 0.12 12.1 3.7 0.58 9.9 0.1 2.6 2 1 1 3 3 3 0 FAM209 family DUF2500 PF10694.4 ETO23913.1 - 0.27 11.2 6.9 1.7 8.6 0.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2500) EphA2_TM PF14575.1 ETO23913.1 - 0.95 9.9 6.5 18 5.7 1.5 3.4 2 1 1 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Pkinase PF00069.20 ETO23914.1 - 7.3e-53 179.3 0.0 8.5e-53 179.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO23914.1 - 3.3e-33 114.8 0.0 3.9e-33 114.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETO23914.1 - 5.1e-06 26.3 0.0 1.3e-05 25.0 0.0 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 ETO23914.1 - 6e-05 22.2 0.0 8.1e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 ETO23914.1 - 0.0055 16.2 0.0 0.0091 15.5 0.0 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 ETO23914.1 - 0.0088 15.4 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.6 ETO23914.1 - 0.017 13.9 0.0 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.4 ETO23914.1 - 0.022 14.0 0.0 0.031 13.6 0.0 1.1 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kinase-like PF14531.1 ETO23914.1 - 0.1 11.5 0.1 0.23 10.4 0.0 1.6 1 1 0 1 1 1 0 Kinase-like RabGAP-TBC PF00566.13 ETO23916.1 - 1.6e-07 31.0 0.0 3.1e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EH_Signature PF15611.1 ETO23916.1 - 0.035 13.1 0.0 0.041 12.9 0.0 1.0 1 0 0 1 1 1 0 EH_Signature domain NRDE-2 PF08424.5 ETO23916.1 - 0.051 12.4 0.4 0.064 12.1 0.3 1.1 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference NDUF_B5 PF09781.4 ETO23916.1 - 0.063 12.5 0.7 0.11 11.7 0.5 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit NICE-3 PF07406.6 ETO23916.1 - 0.11 12.0 0.1 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 NICE-3 protein RNA_pol_Rpb1_5 PF04998.12 ETO23918.1 - 0.36 10.0 3.2 0.67 9.1 2.2 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 WD40 PF00400.27 ETO23919.1 - 4.9e-85 276.6 12.8 3.2e-13 49.0 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO23919.1 - 4.2e-13 49.4 0.1 1.8e-06 27.8 0.0 3.2 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO23919.1 - 4.4e-08 31.7 6.4 0.047 11.8 0.0 5.7 1 1 4 5 5 5 4 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO23919.1 - 8.5e-08 32.0 4.5 0.0012 18.9 0.0 4.8 3 1 1 4 4 4 2 Kelch motif Cytochrom_D1 PF02239.11 ETO23919.1 - 2.2e-06 26.2 1.3 0.087 11.1 0.0 3.8 1 1 3 4 4 4 2 Cytochrome D1 heme domain Kelch_1 PF01344.20 ETO23919.1 - 5.6e-06 25.7 10.6 0.00096 18.6 0.1 5.0 5 0 0 5 5 5 2 Kelch motif PQQ_2 PF13360.1 ETO23919.1 - 4.4e-05 23.0 1.1 0.002 17.6 0.3 2.7 1 1 1 2 2 2 1 PQQ-like domain Kelch_4 PF13418.1 ETO23919.1 - 6e-05 22.7 5.5 0.065 13.0 0.0 5.4 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO23919.1 - 7.2e-05 22.6 5.3 0.11 12.4 0.1 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO23919.1 - 0.00013 22.0 0.1 0.0081 16.3 0.0 3.5 3 0 0 3 3 3 1 Galactose oxidase, central domain Nbas_N PF15492.1 ETO23919.1 - 0.00054 19.1 1.3 1.3 8.0 0.1 4.0 1 1 3 5 5 5 2 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 ETO23919.1 - 0.0015 17.8 0.2 20 4.6 0.0 4.3 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature DUF1258 PF06869.7 ETO23919.1 - 0.0053 15.8 0.9 0.72 8.8 0.0 3.2 2 1 1 3 3 3 1 Protein of unknown function (DUF1258) PD40 PF07676.7 ETO23919.1 - 0.015 14.9 4.8 7.5 6.3 0.0 4.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat CENP-B_dimeris PF09026.5 ETO23920.1 - 0.4 10.9 20.2 0.33 11.2 0.7 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain KorB PF08535.5 ETO23922.1 - 0.29 11.2 0.1 0.29 11.2 0.1 2.6 3 0 0 3 3 3 0 KorB domain DUF2422 PF10337.4 ETO23922.1 - 3.1 6.4 5.5 4.2 6.0 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) TIMP PF00965.12 ETO23923.1 - 0.0085 15.7 0.1 0.0096 15.5 0.1 1.2 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase MBOAT_2 PF13813.1 ETO23923.1 - 0.039 14.0 0.0 0.06 13.4 0.0 1.3 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family DUF1981 PF09324.5 ETO23925.1 - 3.8e-30 103.2 0.5 2e-28 97.7 0.1 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF1981) Sec7 PF01369.15 ETO23926.1 - 4.9e-56 189.4 0.2 1.2e-55 188.0 0.1 1.7 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 ETO23926.1 - 1.8e-06 27.4 0.0 4.8e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF3439 PF11921.3 ETO23926.1 - 0.35 10.6 9.8 0.8 9.4 6.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Band_7 PF01145.20 ETO23928.1 - 9.9e-12 45.1 0.9 2.6e-10 40.5 0.0 2.5 3 0 0 3 3 3 2 SPFH domain / Band 7 family Pkinase PF00069.20 ETO23930.1 - 2.8e-36 125.0 0.0 3.6e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO23930.1 - 5e-14 51.9 0.0 7.8e-14 51.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETO23930.1 - 0.0022 17.7 0.0 0.0038 17.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 ETO23930.1 - 0.011 15.3 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.1 ETO23930.1 - 0.021 13.7 0.0 0.032 13.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like XPG_N PF00752.12 ETO23931.1 - 2.9e-21 75.5 0.0 7.3e-21 74.3 0.0 1.6 2 0 0 2 2 2 1 XPG N-terminal domain MIT PF04212.13 ETO23931.1 - 0.00037 20.3 0.1 0.0008 19.2 0.1 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_8 PF13181.1 ETO23931.1 - 0.0081 15.8 0.7 0.034 13.9 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO23931.1 - 0.015 15.2 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETO23931.1 - 0.024 14.2 0.0 0.06 12.9 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Cas_Csa5 PF09702.5 ETO23931.1 - 0.066 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) zf-C3HC4_3 PF13920.1 ETO23932.1 - 7e-12 44.8 16.6 2.9e-10 39.6 5.7 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO23932.1 - 1.1e-09 37.9 16.9 2.2e-09 36.9 6.9 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO23932.1 - 1.1e-09 38.1 19.8 1.5e-09 37.7 8.0 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO23932.1 - 3.4e-09 36.2 11.3 3.4e-09 36.2 7.9 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO23932.1 - 2.8e-07 30.1 19.2 6.3e-07 29.0 7.5 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 ETO23932.1 - 2.8e-06 27.1 9.4 2.8e-06 27.1 6.5 2.9 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 ETO23932.1 - 8.4e-06 25.4 4.0 8.4e-06 25.4 2.8 3.6 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_6 PF14835.1 ETO23932.1 - 1.6e-05 24.5 6.2 1.6e-05 24.5 4.3 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein U-box PF04564.10 ETO23932.1 - 8.4e-05 22.4 1.2 0.00019 21.3 0.0 2.2 3 0 0 3 3 1 1 U-box domain zf-rbx1 PF12678.2 ETO23932.1 - 0.0002 21.4 15.1 0.00042 20.3 4.9 3.1 2 1 0 2 2 2 1 RING-H2 zinc finger zf-Di19 PF05605.7 ETO23932.1 - 0.0066 16.5 14.0 0.23 11.6 0.5 3.7 3 1 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-RING_4 PF14570.1 ETO23932.1 - 0.019 14.5 13.3 0.028 14.0 1.9 3.4 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 ETO23932.1 - 0.021 14.3 12.5 0.19 11.3 4.5 3.2 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 Paf1 PF03985.8 ETO23932.1 - 0.028 13.1 9.3 0.046 12.4 6.5 1.3 1 0 0 1 1 1 0 Paf1 Ycf1 PF05758.7 ETO23932.1 - 0.057 11.1 8.4 0.067 10.9 5.8 1.1 1 0 0 1 1 1 0 Ycf1 zf-Apc11 PF12861.2 ETO23932.1 - 0.14 12.0 9.4 0.85 9.4 3.6 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF329 PF03884.9 ETO23932.1 - 0.18 11.4 10.4 2.9 7.4 0.1 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF329) RBB1NT PF08169.6 ETO23932.1 - 0.26 11.2 6.0 5.9 6.9 0.2 2.6 2 1 0 2 2 2 0 RBB1NT (NUC162) domain Sgf11 PF08209.6 ETO23932.1 - 0.39 10.0 5.2 5.2 6.4 0.1 3.3 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zinc-ribbons_6 PF07191.7 ETO23932.1 - 2.4 8.0 17.6 4.6 7.0 0.5 3.0 2 2 1 3 3 3 0 zinc-ribbons zinc_ribbon_5 PF13719.1 ETO23932.1 - 7.4 6.2 10.0 6.4 6.4 0.0 3.6 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 ETO23932.1 - 7.5 6.3 10.0 9.1 6.0 0.0 3.7 3 0 0 3 3 3 0 zinc-ribbon domain PRP21_like_P PF12230.3 ETO23932.1 - 7.6 5.9 23.4 0.63 9.5 11.5 2.5 3 1 0 3 3 3 0 Pre-mRNA splicing factor PRP21 like protein tRNA_NucTran2_2 PF13735.1 ETO23933.1 - 0.038 13.8 4.8 0.076 12.8 0.6 2.1 1 1 1 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative DnaJ PF00226.26 ETO23934.1 - 2.3e-14 52.8 0.1 4.3e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain DUF2101 PF09874.4 ETO23934.1 - 0.003 17.0 0.0 0.0047 16.4 0.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2101) TOM20_plant PF06552.7 ETO23934.1 - 0.063 12.8 2.1 0.094 12.2 1.5 1.2 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 AUX_IAA PF02309.11 ETO23934.1 - 0.34 10.6 5.1 0.56 9.9 3.5 1.3 1 0 0 1 1 1 0 AUX/IAA family DFP PF04127.10 ETO23936.1 - 0.00099 18.7 1.0 0.0024 17.4 0.7 1.6 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Baculo_PEP_C PF04513.7 ETO23936.1 - 0.0082 15.9 9.4 0.29 10.9 1.6 2.5 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF740 PF05340.7 ETO23936.1 - 4.7 5.4 9.6 7.5 4.7 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Nucleoplasmin PF03066.10 ETO23936.1 - 5.3 6.5 20.0 12 5.3 13.8 1.6 1 0 0 1 1 1 0 Nucleoplasmin IFT57 PF10498.4 ETO23936.1 - 7.8 5.1 45.1 0.083 11.6 12.2 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Plectin PF00681.15 ETO23937.1 - 0.0044 16.5 0.0 0.014 14.8 0.0 1.9 1 0 0 1 1 1 1 Plectin repeat RPEL PF02755.10 ETO23937.1 - 0.17 11.2 10.8 5.3 6.5 0.0 6.7 7 1 0 7 7 7 0 RPEL repeat Ank_2 PF12796.2 ETO23938.1 - 3.5e-55 184.3 2.7 8.5e-23 80.5 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETO23938.1 - 1.8e-39 131.5 0.8 3.9e-10 39.0 0.1 7.1 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.1 ETO23938.1 - 5.9e-33 109.6 0.7 2e-08 33.6 0.0 7.3 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 ETO23938.1 - 1.1e-28 98.6 1.0 2e-10 40.5 0.0 5.0 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO23938.1 - 1.8e-27 95.1 0.2 3.2e-07 30.6 0.0 5.4 3 2 2 5 5 5 5 Ankyrin repeats (many copies) DUF2802 PF10975.3 ETO23938.1 - 0.036 13.8 0.0 0.077 12.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) Ribosomal_S6 PF01250.12 ETO23938.1 - 0.044 13.6 0.1 0.38 10.6 0.0 2.3 2 1 1 3 3 3 0 Ribosomal protein S6 FAM74 PF15026.1 ETO23939.1 - 0.012 15.2 0.1 0.032 13.8 0.1 1.7 1 0 0 1 1 1 0 FAM74 protein Polysacc_syn_2C PF08485.5 ETO23939.1 - 0.054 13.0 0.4 0.2 11.1 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein C-terminal Ipi1_N PF12333.3 ETO23939.1 - 0.14 12.1 1.5 0.34 10.8 0.1 2.4 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation Alpha_kinase PF02816.13 ETO23941.1 - 2.6e-07 30.4 0.4 6.1e-07 29.2 0.0 1.7 1 1 0 2 2 2 1 Alpha-kinase family SHOCT PF09851.4 ETO23941.1 - 0.024 14.0 0.2 0.024 14.0 0.1 2.0 2 0 0 2 2 2 0 Short C-terminal domain NAD_binding_6 PF08030.7 ETO23941.1 - 0.032 14.1 1.2 0.062 13.1 0.5 1.7 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Kelch_6 PF13964.1 ETO23945.1 - 3e-06 27.1 10.8 0.068 13.3 0.1 5.6 3 1 2 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO23945.1 - 7.5e-06 25.6 2.8 0.27 11.0 0.1 4.7 5 2 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO23945.1 - 1.8e-05 24.1 6.9 0.14 11.6 0.2 5.3 5 1 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 ETO23945.1 - 3.5e-05 23.6 5.6 0.65 10.0 0.1 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 ETO23945.1 - 0.00014 21.9 7.6 0.45 10.7 0.0 5.5 6 1 0 6 6 6 1 Galactose oxidase, central domain Pkinase PF00069.20 ETO23946.1 - 7.5e-15 54.7 0.1 1.4e-14 53.9 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain PH PF00169.24 ETO23946.1 - 6e-13 48.8 1.9 6e-13 48.8 1.3 1.8 2 0 0 2 2 2 1 PH domain Pkinase_Tyr PF07714.12 ETO23946.1 - 2.8e-08 33.1 0.0 5.2e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PH_11 PF15413.1 ETO23946.1 - 0.00035 20.8 4.7 0.02 15.1 2.3 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 ETO23946.1 - 0.007 16.4 0.6 0.007 16.4 0.4 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.1 ETO23946.1 - 0.017 15.1 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain TaqI_C PF12950.2 ETO23946.1 - 0.14 11.9 1.3 0.28 10.9 0.9 1.9 1 1 0 1 1 1 0 TaqI-like C-terminal specificity domain FAM176 PF14851.1 ETO23947.1 - 0.023 14.3 0.0 0.023 14.3 0.0 2.1 2 1 0 2 2 2 0 FAM176 family DUF3270 PF11674.3 ETO23947.1 - 2.2 8.3 11.5 0.8 9.7 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3270) DUF1548 PF07579.6 ETO23948.1 - 0.095 12.8 0.3 0.23 11.5 0.2 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1548) Aldo_ket_red PF00248.16 ETO23949.1 - 1.4e-29 102.8 0.0 1.5e-29 102.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Avl9 PF09794.4 ETO23949.1 - 0.092 11.2 0.0 1.4 7.3 0.0 2.0 1 1 1 2 2 2 0 Transport protein Avl9 Prenyltrans PF00432.16 ETO23950.1 - 3.3e-14 52.1 5.0 3.4e-08 32.9 0.0 4.1 4 0 0 4 4 4 2 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 ETO23950.1 - 1.3e-09 38.3 0.0 2.7e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Prenyltransferase-like Prenyltrans_1 PF13243.1 ETO23950.1 - 0.00043 20.2 0.1 0.13 12.2 0.0 2.5 2 1 0 3 3 3 2 Prenyltransferase-like BAG PF02179.11 ETO23950.1 - 0.11 12.5 0.6 9.8 6.3 0.2 2.6 2 1 0 2 2 2 0 BAG domain Pkinase PF00069.20 ETO23951.1 - 0.00038 19.7 0.1 0.00078 18.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain DUF4131 PF13567.1 ETO23952.1 - 1.4 8.2 12.4 0.72 9.2 0.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) SPC12 PF06645.8 ETO23952.1 - 1.8 8.4 6.6 0.21 11.3 1.2 2.0 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF2721 PF11026.3 ETO23952.1 - 3.1 7.4 6.3 13 5.4 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF106 PF01956.11 ETO23954.1 - 0.00055 19.4 1.5 0.001 18.6 0.1 1.8 2 0 0 2 2 2 1 Integral membrane protein DUF106 Ctr PF04145.10 ETO23954.1 - 0.009 16.0 0.5 0.016 15.2 0.0 1.5 2 0 0 2 2 2 1 Ctr copper transporter family Shisa PF13908.1 ETO23954.1 - 0.0098 16.0 1.1 0.014 15.5 0.8 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator 7tm_1 PF00001.16 ETO23954.1 - 0.02 14.0 0.1 0.02 14.0 0.1 1.5 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) DUF3377 PF11857.3 ETO23954.1 - 0.021 14.4 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) MRJP PF03022.11 ETO23954.1 - 0.021 14.0 0.4 0.021 14.0 0.3 1.5 2 0 0 2 2 2 0 Major royal jelly protein Mem_trans PF03547.13 ETO23954.1 - 0.036 12.3 0.1 0.036 12.3 0.1 1.3 2 0 0 2 2 2 0 Membrane transport protein OATP PF03137.15 ETO23954.1 - 0.041 11.9 0.1 0.056 11.4 0.0 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family 7TM_GPCR_Srv PF10323.4 ETO23954.1 - 0.049 12.7 0.1 0.092 11.8 0.1 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv DUF2946 PF11162.3 ETO23954.1 - 0.052 13.7 0.1 0.075 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) NicO PF03824.11 ETO23954.1 - 0.062 12.6 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein FAM176 PF14851.1 ETO23954.1 - 0.17 11.5 0.0 0.17 11.5 0.0 1.4 2 0 0 2 2 1 0 FAM176 family S1FA PF04689.8 ETO23954.1 - 0.75 9.7 5.9 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 DNA binding protein S1FA SHR3_chaperone PF08229.6 ETO23954.1 - 1.7 7.5 7.1 0.23 10.3 0.1 2.1 2 0 0 2 2 2 0 ER membrane protein SH3 BLVR PF06375.6 ETO23954.1 - 4.9 6.9 9.1 0.58 9.9 1.5 2.0 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Gag_spuma PF03276.9 ETO23954.1 - 9.1 4.4 10.8 13 3.9 7.5 1.1 1 0 0 1 1 1 0 Spumavirus gag protein zf-C3HC4_2 PF13923.1 ETO23955.1 - 6.8e-05 22.8 13.9 0.00016 21.6 9.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO23955.1 - 0.0089 15.6 15.7 0.0089 15.6 10.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO23955.1 - 0.04 13.5 13.8 0.079 12.6 9.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO23955.1 - 0.71 9.7 16.9 0.049 13.4 8.1 1.8 2 0 0 2 2 2 0 Ring finger domain WD40 PF00400.27 ETO23957.1 - 3.4e-55 182.0 29.3 7.3e-10 38.3 0.6 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat zf-TRAF PF02176.13 ETO23957.1 - 2.1e-05 24.8 5.8 2.3e-05 24.6 1.9 2.8 2 0 0 2 2 2 1 TRAF-type zinc finger TSC22 PF01166.13 ETO23957.1 - 0.0045 16.9 0.6 0.022 14.7 0.4 2.3 2 0 0 2 2 2 1 TSC-22/dip/bun family Herpes_BLRF2 PF05812.7 ETO23957.1 - 0.044 13.5 3.1 0.099 12.4 2.0 1.7 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein bZIP_1 PF00170.16 ETO23957.1 - 0.053 13.4 1.2 0.14 12.1 0.9 1.8 1 0 0 1 1 1 0 bZIP transcription factor zf-C3HC4_2 PF13923.1 ETO23957.1 - 4.1 7.5 8.1 1 9.4 0.6 3.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Nt_Gln_amidase PF09764.4 ETO23958.1 - 0.3 10.3 2.1 0.31 10.3 1.3 1.4 1 1 0 1 1 1 0 N-terminal glutamine amidase Pkinase PF00069.20 ETO23959.1 - 0.00063 18.9 0.2 0.0012 18.0 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain DUF1675 PF07897.6 ETO23960.1 - 0.36 10.6 22.1 0.04 13.7 12.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1675) Pkinase PF00069.20 ETO23961.1 - 9.9e-37 126.4 5.4 7e-31 107.3 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO23961.1 - 7.2e-20 71.1 4.3 3.7e-18 65.5 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.9 ETO23961.1 - 0.00028 20.0 0.5 0.0016 17.5 0.0 2.3 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETO23961.1 - 0.019 13.9 0.0 0.039 12.8 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 ETO23961.1 - 0.024 14.3 1.6 0.096 12.3 0.1 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family RB_A PF01858.12 ETO23961.1 - 4.7 6.8 12.0 3.6 7.2 0.2 3.3 3 0 0 3 3 3 0 Retinoblastoma-associated protein A domain DUF4199 PF13858.1 ETO23964.1 - 0.0027 17.6 0.5 0.0054 16.6 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) Mem_trans PF03547.13 ETO23965.1 - 0.45 8.7 1.6 0.63 8.2 1.1 1.3 1 0 0 1 1 1 0 Membrane transport protein Hid1 PF12722.2 ETO23965.1 - 2.8 5.4 15.3 3.3 5.2 10.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4175 PF13779.1 ETO23965.1 - 6.9 4.2 16.2 9.4 3.7 11.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FLO_LFY PF01698.11 ETO23965.1 - 8.1 5.1 11.7 8.5 5.1 8.1 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Kelch_3 PF13415.1 ETO23967.1 - 1.3e-25 88.9 0.0 7.8e-11 41.8 0.0 3.0 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO23967.1 - 7.7e-23 80.0 0.0 1e-11 44.4 0.0 2.2 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO23967.1 - 2.7e-19 68.4 0.2 1.3e-08 34.6 0.1 2.1 1 1 1 2 2 2 2 Kelch motif Kelch_1 PF01344.20 ETO23967.1 - 1.1e-15 56.8 0.1 9.3e-08 31.4 0.1 2.2 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.1 ETO23967.1 - 1.4e-14 53.6 0.1 3.5e-06 26.8 0.0 2.7 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 ETO23967.1 - 2.1e-10 39.9 0.3 0.00025 20.6 0.0 2.3 2 0 0 2 2 2 2 Kelch motif Rax2 PF12768.2 ETO23967.1 - 0.0061 15.8 0.0 0.0075 15.5 0.0 1.1 1 0 0 1 1 1 1 Cortical protein marker for cell polarity B12-binding PF02310.14 ETO23968.1 - 5.5e-11 42.3 0.6 2.9e-08 33.6 0.0 2.1 2 0 0 2 2 2 2 B12 binding domain WD40 PF00400.27 ETO23969.1 - 7.5e-10 38.3 0.4 0.087 12.7 0.0 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat CRT10 PF08728.5 ETO23969.1 - 0.0072 14.3 0.1 0.037 12.0 0.0 1.8 2 0 0 2 2 2 1 CRT10 CPSF_A PF03178.10 ETO23969.1 - 0.0077 15.3 0.1 0.35 9.9 0.0 2.4 1 1 1 2 2 2 1 CPSF A subunit region PQQ_3 PF13570.1 ETO23969.1 - 0.041 14.1 0.5 2.6 8.4 0.0 3.4 3 1 1 4 4 4 0 PQQ-like domain Abhydrolase_6 PF12697.2 ETO23970.1 - 5.5e-11 42.7 0.0 7e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETO23970.1 - 1.3e-09 38.0 0.1 1.7e-09 37.6 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETO23970.1 - 3.4e-05 23.6 0.0 4.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 ETO23970.1 - 0.069 13.3 0.0 0.092 12.9 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.8 ETO23970.1 - 0.091 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold PRELI PF04707.9 ETO23971.1 - 0.037 13.6 0.3 0.98 8.9 0.0 2.4 2 0 0 2 2 2 0 PRELI-like family Virulence_RhuM PF13310.1 ETO23974.1 - 0.042 12.8 0.5 0.061 12.3 0.4 1.2 1 0 0 1 1 1 0 Virulence protein RhuM family SDA1 PF05285.7 ETO23974.1 - 1.4 8.1 16.9 1.9 7.6 11.7 1.1 1 0 0 1 1 1 0 SDA1 LMBR1 PF04791.11 ETO23974.1 - 4.1 5.8 6.0 4 5.9 4.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Carboxyl_trans PF01039.17 ETO23976.1 - 1.9e-116 389.3 0.0 1.1e-110 370.2 0.0 2.7 3 0 0 3 3 3 2 Carboxyl transferase domain ACC_central PF08326.7 ETO23976.1 - 6.1e-88 295.7 0.7 1.2e-45 155.9 0.9 2.3 2 0 0 2 2 2 2 Acetyl-CoA carboxylase, central region CPSase_L_D2 PF02786.12 ETO23976.1 - 1.8e-48 164.6 0.0 3.5e-48 163.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 ETO23976.1 - 1.6e-25 89.1 0.0 5.8e-25 87.3 0.0 2.1 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 ETO23976.1 - 1.1e-16 60.9 0.0 3e-16 59.4 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 ETO23976.1 - 2.6e-11 43.6 0.0 7.3e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 ETO23976.1 - 3.6e-10 39.3 0.1 7.3e-10 38.3 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 ETO23976.1 - 6.7e-05 22.3 0.0 0.00016 21.1 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 ETO23976.1 - 0.00085 18.7 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 ETO23976.1 - 0.00096 18.7 0.4 0.0045 16.6 0.0 2.3 2 0 0 2 2 2 1 Biotin-lipoyl like Utp14 PF04615.8 ETO23977.1 - 1e-32 113.2 60.1 1.4e-20 73.0 15.3 2.2 1 1 1 2 2 2 2 Utp14 protein EFG_II PF14492.1 ETO23978.1 - 9.5e-05 22.1 0.0 0.00027 20.7 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II Nop14 PF04147.7 ETO23978.1 - 0.0065 14.4 35.5 0.0092 13.9 24.6 1.1 1 0 0 1 1 1 1 Nop14-like family MIP-T3 PF10243.4 ETO23978.1 - 0.018 13.5 22.6 0.022 13.2 15.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SDA1 PF05285.7 ETO23978.1 - 0.033 13.4 28.0 0.042 13.1 19.4 1.2 1 0 0 1 1 1 0 SDA1 Ycf1 PF05758.7 ETO23978.1 - 0.034 11.8 10.4 0.044 11.5 7.2 1.2 1 0 0 1 1 1 0 Ycf1 Paf1 PF03985.8 ETO23978.1 - 0.32 9.6 29.6 0.53 8.9 20.5 1.3 1 0 0 1 1 1 0 Paf1 DUF2457 PF10446.4 ETO23978.1 - 0.71 8.5 38.5 1.3 7.6 26.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TIMELESS_C PF05029.8 ETO23978.1 - 0.78 8.5 27.7 1.2 8.0 19.2 1.1 1 0 0 1 1 1 0 Timeless protein C terminal region DUF1510 PF07423.6 ETO23978.1 - 1.5 8.1 29.6 3.3 7.0 20.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TFIIF_alpha PF05793.7 ETO23978.1 - 2.4 6.4 34.0 0.13 10.6 20.1 1.4 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nucleo_P87 PF07267.6 ETO23978.1 - 4.9 5.7 15.0 9.5 4.7 10.4 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RR_TM4-6 PF06459.7 ETO23978.1 - 8.3 6.2 19.3 17 5.1 13.4 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EFG_C PF00679.19 ETO23979.1 - 7.8e-10 38.4 0.0 1.2e-06 28.2 0.0 2.6 3 0 0 3 3 3 2 Elongation factor G C-terminus EFG_IV PF03764.13 ETO23979.1 - 5.9e-05 22.6 0.0 0.00012 21.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV CDC45 PF02724.9 ETO23979.1 - 2.7 5.9 6.6 4.6 5.1 4.6 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 ETO23979.1 - 6 5.4 12.3 0.088 11.5 3.6 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Glypican PF01153.14 ETO23980.1 - 0.017 13.7 1.2 0.025 13.2 0.8 1.3 1 0 0 1 1 1 0 Glypican DUF1949 PF09186.6 ETO23980.1 - 0.16 11.6 0.8 6.9 6.3 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1949) YfhO PF09586.5 ETO23980.1 - 7.9 4.3 7.8 1.2 7.0 1.7 1.8 2 0 0 2 2 2 0 Bacterial membrane protein YfhO DUF4065 PF13274.1 ETO23981.1 - 0.018 15.7 12.4 0.038 14.7 4.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4065) PRP1_N PF06424.7 ETO23981.1 - 1.1 9.5 26.4 0.13 12.5 7.1 3.1 3 0 0 3 3 3 0 PRP1 splicing factor, N-terminal Methyltransf_12 PF08242.7 ETO23981.1 - 2 8.9 11.1 3.9 8.0 1.3 2.7 2 0 0 2 2 2 0 Methyltransferase domain SMC_Nse1 PF07574.8 ETO23982.1 - 0.00012 21.8 0.8 0.00014 21.5 0.0 1.4 2 0 0 2 2 2 1 Nse1 non-SMC component of SMC5-6 complex Peptidase_M15_3 PF08291.6 ETO23982.1 - 0.017 14.9 0.4 0.024 14.4 0.2 1.3 1 1 0 1 1 1 0 Peptidase M15 Sec8_exocyst PF04048.9 ETO23982.1 - 0.029 13.9 3.9 1.1 8.8 0.5 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Radical_SAM PF04055.16 ETO23982.1 - 0.034 14.2 0.1 0.04 14.0 0.1 1.3 1 0 0 1 1 1 0 Radical SAM superfamily GlcNAc PF11397.3 ETO23982.1 - 0.061 12.4 0.1 0.079 12.0 0.1 1.1 1 0 0 1 1 1 0 Glycosyltransferase (GlcNAc) Vps5 PF09325.5 ETO23982.1 - 0.064 12.5 0.2 0.064 12.5 0.1 2.0 2 0 0 2 2 2 0 Vps5 C terminal like CorA PF01544.13 ETO23982.1 - 0.067 12.2 0.6 0.99 8.3 0.0 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Spectrin PF00435.16 ETO23982.1 - 0.075 13.3 3.0 3.1 8.1 0.4 2.2 2 0 0 2 2 2 0 Spectrin repeat Fib_alpha PF08702.5 ETO23982.1 - 0.14 12.2 6.1 2 8.5 0.3 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF745 PF05335.8 ETO23982.1 - 0.14 11.6 4.2 0.3 10.5 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) TraF_2 PF13729.1 ETO23982.1 - 0.15 10.8 1.1 0.2 10.3 0.1 1.6 2 0 0 2 2 2 0 F plasmid transfer operon, TraF, protein Prefoldin_2 PF01920.15 ETO23982.1 - 0.15 11.8 10.3 1.8 8.3 0.1 2.4 2 1 0 2 2 2 0 Prefoldin subunit Glyco_hydro_4C PF11975.3 ETO23982.1 - 0.24 11.1 2.3 0.3 10.8 1.6 1.1 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain Syntaxin PF00804.20 ETO23982.1 - 0.26 11.4 6.1 0.49 10.5 0.2 2.2 1 1 1 2 2 2 0 Syntaxin Med9 PF07544.8 ETO23982.1 - 0.33 10.7 5.4 8.2 6.2 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Prefoldin PF02996.12 ETO23982.1 - 0.38 10.4 10.2 1 8.9 0.0 2.2 2 0 0 2 2 2 0 Prefoldin subunit Flu_NS2 PF00601.14 ETO23982.1 - 0.44 10.7 2.7 2.4 8.4 0.2 2.1 1 1 1 2 2 2 0 Influenza non-structural protein (NS2) RPW8 PF05659.6 ETO23982.1 - 0.48 9.9 5.7 6 6.4 1.9 2.2 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF1682 PF07946.9 ETO23982.1 - 0.71 8.6 7.3 1 8.1 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) FlaG PF03646.10 ETO23982.1 - 0.72 10.0 5.6 3.2 7.9 0.1 2.3 1 1 1 2 2 2 0 FlaG protein TPR_MLP1_2 PF07926.7 ETO23982.1 - 0.97 9.1 10.5 7.6 6.2 4.3 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Seryl_tRNA_N PF02403.17 ETO23982.1 - 2 8.4 14.0 3.7 7.5 6.5 2.3 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain ING PF12998.2 ETO23982.1 - 2.6 8.3 8.2 14 6.0 5.7 1.9 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Syntaxin_2 PF14523.1 ETO23982.1 - 2.7 8.0 6.5 24 5.0 4.5 2.1 1 1 0 1 1 1 0 Syntaxin-like protein DUF4200 PF13863.1 ETO23982.1 - 5.7 6.9 15.6 4.8 7.1 6.6 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) Spc7 PF08317.6 ETO23982.1 - 7.9 5.0 10.5 27 3.2 7.3 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein WD40 PF00400.27 ETO23983.1 - 1.7e-74 243.2 24.4 3.3e-13 48.9 0.7 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO23983.1 - 6.8e-08 32.4 0.7 3.7e-05 23.5 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO23983.1 - 6.8e-07 27.7 4.1 0.00055 18.1 0.6 3.2 1 1 2 3 3 3 2 Nucleoporin Nup120/160 DUF1258 PF06869.7 ETO23983.1 - 5.2e-06 25.7 4.1 0.015 14.3 0.1 4.5 1 1 5 6 6 6 1 Protein of unknown function (DUF1258) Cytochrom_D1 PF02239.11 ETO23983.1 - 0.0018 16.6 0.1 0.023 13.0 0.0 2.3 2 1 1 3 3 3 1 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 ETO23983.1 - 0.0025 17.0 0.6 8.1 5.8 0.0 3.5 3 0 0 3 3 3 2 Proteasome subunit A N-terminal signature SGL PF08450.7 ETO23983.1 - 0.0041 16.5 0.4 0.015 14.6 0.1 2.1 1 1 1 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Nucleoporin_N PF08801.6 ETO23983.1 - 0.0042 15.9 7.4 0.024 13.3 0.4 3.9 1 1 0 3 3 3 1 Nup133 N terminal like PD40 PF07676.7 ETO23983.1 - 0.53 10.0 6.2 7.1 6.4 0.1 4.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat RPEL PF02755.10 ETO23984.1 - 7.7e-11 40.9 5.2 0.0016 17.7 1.6 3.9 3 1 0 3 3 3 3 RPEL repeat DUF4174 PF13778.1 ETO23984.1 - 0.084 12.9 1.6 1.6 8.8 0.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4174) Exonuc_VII_L PF02601.10 ETO23984.1 - 9.9 5.2 12.3 0.95 8.5 5.5 1.6 1 1 1 2 2 2 0 Exonuclease VII, large subunit C2 PF00168.25 ETO23985.1 - 5.3e-08 32.5 0.1 2.3e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 C2 domain TFIIA PF03153.8 ETO23987.1 - 6.3 6.5 12.3 7.3 6.3 8.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CAP_GLY PF01302.20 ETO23988.1 - 1e-38 130.8 4.6 2.6e-20 71.8 0.2 2.5 2 0 0 2 2 2 2 CAP-Gly domain DUF1510 PF07423.6 ETO23988.1 - 3.8 6.8 29.6 2.4 7.4 7.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) Pkinase PF00069.20 ETO23989.1 - 1.1e-71 241.0 0.0 2.1e-71 240.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO23989.1 - 4.4e-33 114.4 0.0 7.3e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Myosin_TH1 PF06017.8 ETO23989.1 - 5.2e-12 45.4 3.5 7.4e-12 44.9 1.8 1.7 2 1 0 2 2 2 1 Myosin tail Pkinase_C PF00433.19 ETO23989.1 - 0.00029 21.2 0.1 0.00098 19.5 0.1 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 ETO23989.1 - 0.00059 18.8 0.0 0.015 14.2 0.0 2.2 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 ETO23989.1 - 0.0092 15.0 0.0 0.017 14.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TT_ORF2 PF02957.10 ETO23989.1 - 0.011 16.4 0.4 0.025 15.2 0.3 1.6 1 0 0 1 1 1 0 TT viral ORF2 hSac2 PF12456.3 ETO23989.1 - 0.018 14.4 0.0 0.043 13.2 0.0 1.6 1 0 0 1 1 1 0 Inositol phosphatase Glyco_transf_8 PF01501.15 ETO23990.1 - 7.4e-13 48.4 0.9 2e-12 46.9 0.6 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 ETO23990.1 - 0.021 14.6 0.1 0.039 13.7 0.1 1.4 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Ras PF00071.17 ETO23991.1 - 3.2e-08 33.1 0.5 0.0082 15.5 0.0 2.8 2 1 0 2 2 2 2 Ras family GTP_EFTU PF00009.22 ETO23991.1 - 0.0069 15.8 0.0 0.016 14.6 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 ETO23991.1 - 0.0096 16.4 2.6 0.14 12.6 0.3 3.0 2 2 1 3 3 3 1 Miro-like protein Arf PF00025.16 ETO23991.1 - 0.026 13.7 0.4 13 5.0 0.1 3.1 2 1 0 2 2 2 0 ADP-ribosylation factor family Baculo_Y142 PF04913.7 ETO23991.1 - 0.04 12.2 0.1 0.059 11.7 0.1 1.2 1 0 0 1 1 1 0 Baculovirus Y142 protein DUF946 PF06101.6 ETO23992.1 - 3.8e-07 28.4 1.1 2.2e-06 26.0 0.8 1.9 1 1 0 1 1 1 1 Plant protein of unknown function (DUF946) ATG16 PF08614.6 ETO23993.1 - 0.011 15.5 1.0 0.016 15.0 0.7 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Zip PF02535.17 ETO23993.1 - 0.02 13.9 1.2 0.022 13.7 0.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Beach PF02138.13 ETO23995.1 - 1.4e-101 339.5 0.3 1.9e-101 339.0 0.2 1.1 1 0 0 1 1 1 1 Beige/BEACH domain Med15 PF09606.5 ETO23997.1 - 0.00061 18.1 3.5 0.00074 17.8 2.4 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal FimP PF09766.4 ETO23997.1 - 0.023 13.7 9.7 0.092 11.8 3.0 2.2 2 0 0 2 2 2 0 Fms-interacting protein Zip PF02535.17 ETO23997.1 - 0.025 13.5 0.5 0.041 12.8 0.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3306 PF11748.3 ETO23997.1 - 0.038 14.6 2.7 0.038 14.6 1.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3306) Merozoite_SPAM PF07133.6 ETO23997.1 - 0.079 12.8 18.3 0.42 10.4 8.1 2.3 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) DUF3439 PF11921.3 ETO23997.1 - 0.16 11.6 6.4 0.29 10.8 4.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 ETO23997.1 - 0.65 7.9 10.2 0.86 7.5 7.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Nucleoplasmin PF03066.10 ETO23997.1 - 1.1 8.7 15.2 0.14 11.6 4.1 2.5 2 0 0 2 2 2 0 Nucleoplasmin Mak16 PF04874.9 ETO23997.1 - 3 8.0 20.1 1.2 9.2 8.3 2.9 3 0 0 3 3 3 0 Mak16 protein C-terminal region ubiquitin PF00240.18 ETO23998.1 - 2.5e-07 29.9 0.1 4.9e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 ETO23998.1 - 1.7e-06 28.2 0.1 3.2e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.3 ETO23998.1 - 0.0054 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Cytochrom_B_N_2 PF13631.1 ETO23998.1 - 0.0058 16.4 0.7 0.011 15.5 0.5 1.4 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB UN_NPL4 PF11543.3 ETO23998.1 - 0.056 13.7 0.2 0.099 12.9 0.2 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 zf-RING_2 PF13639.1 ETO23999.1 - 0.0044 16.8 20.5 0.0094 15.7 14.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.1 ETO23999.1 - 0.011 15.4 7.0 0.02 14.6 4.8 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.1 ETO23999.1 - 0.012 15.2 15.2 0.025 14.2 10.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO23999.1 - 0.028 14.4 21.6 0.064 13.3 15.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 ETO23999.1 - 0.75 9.7 14.9 12 5.9 11.0 2.4 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 ETO23999.1 - 3.3 7.5 16.8 9.2 6.0 11.6 1.8 1 0 0 1 1 1 0 zinc-RING finger domain Vps39_2 PF10367.4 ETO23999.1 - 4.4 7.5 11.5 8.2 6.6 4.9 2.5 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 RRP7 PF12923.2 ETO23999.1 - 4.4 7.3 12.4 0.27 11.2 3.8 2.3 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) vMSA PF00695.14 ETO24000.1 - 0.15 11.2 7.6 0.18 11.0 5.3 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus DASH_Spc34 PF08657.5 ETO24000.1 - 0.9 9.1 15.8 1.1 8.8 10.9 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 Pol_alpha_B_N PF08418.5 ETO24000.1 - 1.3 8.5 16.6 1.5 8.3 11.5 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Strabismus PF06638.6 ETO24000.1 - 2.4 6.3 8.3 3.1 5.9 5.7 1.1 1 0 0 1 1 1 0 Strabismus protein DEP PF00610.16 ETO24001.1 - 4.7e-09 35.8 0.0 1.2e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RXT2_N PF08595.6 ETO24002.1 - 0.54 10.0 5.3 0.18 11.6 1.8 1.6 2 0 0 2 2 2 0 RXT2-like, N-terminal Utp14 PF04615.8 ETO24003.1 - 0.86 7.6 25.2 1.2 7.2 17.5 1.1 1 0 0 1 1 1 0 Utp14 protein RhoGAP PF00620.22 ETO24004.1 - 1.3e-07 31.3 0.6 2.8e-07 30.2 0.4 1.5 1 1 0 1 1 1 1 RhoGAP domain Pro_CA PF00484.14 ETO24004.1 - 0.024 14.6 0.1 0.04 13.9 0.1 1.3 1 0 0 1 1 1 0 Carbonic anhydrase SPT16 PF08644.6 ETO24004.1 - 0.099 12.4 0.2 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) EMP70 PF02990.11 ETO24005.1 - 3.8e-59 200.5 23.0 4.6e-59 200.2 16.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 DUF3309 PF11752.3 ETO24005.1 - 0.35 10.6 8.2 0.082 12.6 0.9 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3309) Cortexin PF11057.3 ETO24005.1 - 4.5 6.9 5.8 1.6 8.3 0.6 2.3 2 0 0 2 2 2 0 Cortexin of kidney Pex24p PF06398.6 ETO24005.1 - 9 4.9 10.2 2 7.1 4.8 1.5 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin MFS_2 PF13347.1 ETO24006.1 - 2.2e-07 29.6 7.1 4.9e-07 28.4 4.9 1.7 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.11 ETO24006.1 - 3.2e-07 29.4 4.3 4.2e-07 28.9 1.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.10 ETO24006.1 - 0.035 12.8 0.0 0.055 12.1 0.0 1.3 1 0 0 1 1 1 0 PUCC protein DUF912 PF06024.7 ETO24007.1 - 0.045 13.7 1.0 0.31 11.1 0.0 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF566 PF04484.7 ETO24007.1 - 0.16 11.4 10.3 0.2 11.1 7.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Rifin_STEVOR PF02009.11 ETO24007.1 - 0.23 11.0 6.3 0.47 10.0 4.2 1.5 1 1 1 2 2 2 0 Rifin/stevor family COX6A PF02046.10 ETO24007.1 - 0.27 11.1 0.1 0.27 11.1 0.1 1.7 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIa Patatin PF01734.17 ETO24007.1 - 1.9 8.3 0.0 1.9 8.3 0.0 2.6 2 1 0 2 2 2 0 Patatin-like phospholipase TP53IP5 PF15331.1 ETO24007.1 - 2.3 8.0 7.1 3.2 7.6 4.9 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 zf-RING_2 PF13639.1 ETO24008.1 - 6.6e-13 48.2 9.6 2e-12 46.7 6.6 1.9 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 ETO24008.1 - 4.4e-07 29.9 11.3 4.4e-07 29.9 7.8 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 ETO24008.1 - 6.3e-06 25.7 9.5 6.3e-06 25.7 6.6 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO24008.1 - 0.00018 21.0 6.8 0.00039 20.0 4.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO24008.1 - 0.00028 20.8 10.7 0.00035 20.5 6.3 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO24008.1 - 0.00053 19.6 8.9 0.00053 19.6 6.2 2.0 2 0 0 2 2 2 1 zinc-RING finger domain UPF0093 PF03653.8 ETO24008.1 - 0.1 12.5 0.1 0.1 12.5 0.1 2.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0093) Rad50_zn_hook PF04423.9 ETO24008.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-Apc11 PF12861.2 ETO24008.1 - 0.13 12.1 13.2 0.14 12.0 7.1 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 ETO24008.1 - 0.82 9.7 10.6 2.5 8.1 7.3 1.9 1 0 0 1 1 1 0 RING-variant domain EMP70 PF02990.11 ETO24009.1 - 7.8e-16 57.6 0.0 1.2e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Endomembrane protein 70 AAA_11 PF13086.1 ETO24010.1 - 3.9e-58 196.8 0.3 6.9e-58 196.0 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 ETO24010.1 - 4.5e-28 97.9 0.3 1.3e-27 96.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 ETO24010.1 - 7.6e-14 51.2 0.1 4.6e-12 45.5 0.0 3.0 3 0 0 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 ETO24010.1 - 1.3e-10 41.2 0.0 3.8e-08 33.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.1 ETO24010.1 - 2.8e-06 27.8 1.2 2.8e-06 27.8 0.8 2.5 1 1 1 2 2 2 1 AAA domain DEAD PF00270.24 ETO24010.1 - 5.9e-05 22.6 0.3 0.0011 18.4 0.2 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.4 ETO24010.1 - 6.9e-05 21.9 0.8 0.12 11.2 0.0 3.1 2 1 1 3 3 3 2 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 ETO24010.1 - 0.0003 20.3 0.3 0.65 9.4 0.0 2.6 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 ETO24010.1 - 0.00061 19.6 0.0 0.004 17.0 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 ETO24010.1 - 0.00074 19.6 0.4 0.038 14.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETO24010.1 - 0.0013 18.7 0.7 0.0047 16.9 0.2 2.3 2 1 0 2 2 2 1 AAA ATPase domain UvrD-helicase PF00580.16 ETO24010.1 - 0.0035 16.6 2.0 0.021 14.1 0.3 2.6 1 1 2 3 3 3 1 UvrD/REP helicase N-terminal domain Atg14 PF10186.4 ETO24010.1 - 0.0064 15.4 1.4 0.012 14.5 1.0 1.4 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 ETO24010.1 - 0.011 15.3 1.8 0.021 14.4 0.4 2.0 2 0 0 2 2 2 0 IncA protein AAA PF00004.24 ETO24010.1 - 0.012 15.8 2.8 0.11 12.7 1.9 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SNF2_N PF00176.18 ETO24010.1 - 0.019 13.7 0.0 0.038 12.7 0.0 1.5 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_17 PF13207.1 ETO24010.1 - 0.026 15.3 1.0 0.13 13.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 ETO24010.1 - 0.031 13.4 0.4 0.089 11.8 0.0 1.9 2 1 1 3 3 3 0 KaiC FtsK_SpoIIIE PF01580.13 ETO24010.1 - 0.036 13.5 0.0 0.087 12.2 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_25 PF13481.1 ETO24010.1 - 0.041 13.2 0.0 0.27 10.6 0.0 2.4 3 0 0 3 3 3 0 AAA domain Zot PF05707.7 ETO24010.1 - 0.044 13.2 0.0 0.19 11.1 0.0 2.1 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_24 PF13479.1 ETO24010.1 - 0.044 13.3 0.0 0.27 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 ETO24010.1 - 0.058 13.1 2.5 3.3 7.3 0.0 3.6 2 1 2 4 4 4 0 NTPase RNA_helicase PF00910.17 ETO24010.1 - 0.076 13.1 0.1 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase T2SE PF00437.15 ETO24010.1 - 0.08 11.8 0.1 0.19 10.6 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_33 PF13671.1 ETO24010.1 - 0.084 12.7 1.1 0.2 11.5 0.2 2.3 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 ETO24010.1 - 0.094 12.1 0.3 0.63 9.4 0.0 2.3 1 1 0 2 2 2 0 AAA-like domain cobW PF02492.14 ETO24010.1 - 0.1 12.0 2.2 5.9 6.3 0.0 2.8 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 ETO24010.1 - 0.18 12.1 2.1 0.77 10.0 0.0 3.0 4 0 0 4 4 3 0 AAA domain DUF1664 PF07889.7 ETO24010.1 - 0.18 11.5 2.6 11 5.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Lipase_GDSL_2 PF13472.1 ETO24011.1 - 0.07 13.2 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family CAF-1_p150 PF11600.3 ETO24012.1 - 0.13 11.5 48.7 0.35 10.2 33.8 1.7 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CDC27 PF09507.5 ETO24012.1 - 0.16 11.1 40.0 0.2 10.8 27.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Med15 PF09606.5 ETO24012.1 - 0.81 7.8 34.7 0.97 7.5 24.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Peptidase_S64 PF08192.6 ETO24012.1 - 1.9 6.7 27.2 2.5 6.3 18.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 TFIIA PF03153.8 ETO24012.1 - 2.2 8.1 32.5 3 7.6 22.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PHO4 PF01384.15 ETO24013.1 - 0.0095 14.6 0.0 0.011 14.4 0.0 1.2 1 0 0 1 1 1 1 Phosphate transporter family Thioredoxin_2 PF13098.1 ETO24013.1 - 0.021 15.0 0.7 0.051 13.7 0.5 1.7 1 1 1 2 2 2 0 Thioredoxin-like domain Patched PF02460.13 ETO24014.1 - 2.7e-12 45.4 9.2 3.6e-12 45.0 6.4 1.1 1 0 0 1 1 1 1 Patched family PAN_1 PF00024.21 ETO24014.1 - 0.059 13.1 11.0 0.056 13.1 1.8 2.4 2 0 0 2 2 2 0 PAN domain DUF1977 PF09320.6 ETO24017.1 - 4e-06 27.0 14.4 1.6e-05 25.0 10.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1977) YfhO PF09586.5 ETO24017.1 - 0.11 10.4 3.4 0.16 9.9 2.4 1.3 1 0 0 1 1 1 0 Bacterial membrane protein YfhO MAS20 PF02064.10 ETO24017.1 - 0.12 12.2 2.9 0.28 11.1 2.0 1.5 1 0 0 1 1 1 0 MAS20 protein import receptor DUF1796 PF08795.5 ETO24017.1 - 0.33 10.5 5.1 0.66 9.5 3.5 1.4 1 1 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) Effector_1 PF04518.7 ETO24017.1 - 1.5 7.6 9.2 0.061 12.3 0.3 1.9 1 1 1 2 2 2 0 Effector from type III secretion system MspA PF09203.6 ETO24018.1 - 0.84 9.0 17.3 0.067 12.6 6.9 2.5 2 1 0 2 2 2 0 MspA Neur_chan_memb PF02932.11 ETO24018.1 - 7.1 6.4 12.5 2.2 8.1 0.4 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Ras PF00071.17 ETO24021.1 - 1.2e-24 86.5 0.3 1.6e-24 86.0 0.2 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO24021.1 - 4e-05 24.0 0.1 0.00011 22.6 0.0 1.8 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO24021.1 - 0.0037 16.5 0.1 0.0056 15.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family HA2 PF04408.18 ETO24022.1 - 4.3e-23 81.2 0.0 9e-23 80.2 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 ETO24022.1 - 1.9e-11 43.6 0.1 1.3e-10 40.9 0.1 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETO24022.1 - 0.00033 20.1 0.4 0.0017 17.8 0.2 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase UPF0184 PF03670.8 ETO24022.1 - 0.019 15.1 0.1 0.046 13.9 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Acetyltransf_1 PF00583.19 ETO24023.1 - 0.00011 22.2 0.0 0.00016 21.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETO24023.1 - 0.00037 20.6 0.0 0.00061 19.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETO24023.1 - 0.039 14.0 0.0 0.051 13.6 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1653 PF07866.6 ETO24024.1 - 0.059 13.5 0.1 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1653) SieB PF14163.1 ETO24024.1 - 0.11 12.0 0.4 0.19 11.2 0.3 1.3 1 0 0 1 1 1 0 Superinfection exclusion protein B DUF4600 PF15372.1 ETO24025.1 - 0.1 12.8 0.6 0.1 12.8 0.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) Trypsin PF00089.21 ETO24026.1 - 3.6e-09 36.5 0.1 2.2e-08 33.9 0.1 1.9 1 1 0 1 1 1 1 Trypsin Helicase_C_2 PF13307.1 ETO24027.1 - 2.1e-52 177.4 0.2 4.8e-52 176.2 0.1 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 ETO24027.1 - 4.1e-33 114.2 8.2 4.1e-33 114.2 5.7 2.1 2 0 0 2 2 2 1 DEAD_2 Prefoldin_2 PF01920.15 ETO24028.1 - 3.2e-13 49.3 12.6 4.6e-13 48.8 8.7 1.2 1 0 0 1 1 1 1 Prefoldin subunit Lectin_N PF03954.9 ETO24028.1 - 0.019 14.3 1.2 0.023 14.0 0.1 1.7 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain HTH_6 PF01418.12 ETO24028.1 - 0.097 12.4 1.4 0.25 11.0 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family DivIC PF04977.10 ETO24028.1 - 0.12 11.8 10.4 1.1 8.7 2.0 2.6 1 1 1 2 2 2 0 Septum formation initiator Atg14 PF10186.4 ETO24028.1 - 0.34 9.8 5.7 0.44 9.4 4.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3584 PF12128.3 ETO24028.1 - 0.64 7.2 7.7 0.8 6.9 5.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc24 PF08286.6 ETO24028.1 - 0.8 9.4 9.9 0.085 12.5 1.4 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Osmo_CC PF08946.5 ETO24028.1 - 1.6 8.8 5.0 0.48 10.5 0.9 2.0 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Toxin_17 PF08086.6 ETO24029.1 - 0.043 13.8 0.4 0.11 12.5 0.3 1.7 1 0 0 1 1 1 0 Ergtoxin family LMBR1 PF04791.11 ETO24029.1 - 8.5 4.8 6.8 37 2.7 4.4 2.2 1 1 0 1 1 1 0 LMBR1-like membrane protein Phyto_Pns9_10 PF05878.6 ETO24030.1 - 0.00029 19.9 4.7 0.00046 19.2 3.2 1.3 1 0 0 1 1 1 1 Phytoreovirus nonstructural protein Pns9/Pns10 CDC45 PF02724.9 ETO24030.1 - 0.0069 14.4 5.4 0.008 14.2 3.8 1.2 1 0 0 1 1 1 1 CDC45-like protein Mitofilin PF09731.4 ETO24030.1 - 0.055 12.1 10.2 0.069 11.7 7.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Neur_chan_memb PF02932.11 ETO24030.1 - 0.09 12.6 1.1 0.11 12.3 0.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Nop14 PF04147.7 ETO24030.1 - 1.1 7.0 18.0 1.6 6.5 12.5 1.2 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 ETO24030.1 - 3.7 5.9 18.6 4.8 5.5 12.9 1.1 1 0 0 1 1 1 0 Daxx Family DEAD PF00270.24 ETO24031.1 - 5.1e-19 68.3 0.4 9.9e-19 67.4 0.2 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETO24031.1 - 1.8e-13 50.1 0.0 4.4e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 ETO24031.1 - 0.001 18.1 0.1 0.0021 17.1 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.1 ETO24031.1 - 0.017 14.8 0.0 0.084 12.6 0.0 2.1 2 1 0 2 2 2 0 Part of AAA domain Borrelia_P13 PF05628.7 ETO24032.1 - 0.018 14.8 1.9 0.046 13.5 0.5 2.2 2 0 0 2 2 2 0 Borrelia membrane protein P13 DUF843 PF05814.6 ETO24033.1 - 0.3 10.8 5.4 0.21 11.3 0.3 3.0 3 0 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) PBAN PF05874.6 ETO24034.1 - 0.016 14.5 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Pheromone biosynthesis activating neuropeptide (PBAN) SIP1 PF04938.7 ETO24035.1 - 0.079 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) ABC_tran PF00005.22 ETO24036.1 - 8.4e-09 35.8 0.0 1.4e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 ETO24036.1 - 0.0011 19.0 0.4 0.0044 17.0 0.0 1.9 1 1 1 2 2 2 1 AAA domain SMC_N PF02463.14 ETO24036.1 - 0.017 14.3 0.1 0.031 13.5 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 ETO24036.1 - 0.044 13.3 0.0 0.093 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 ETO24036.1 - 0.046 14.0 0.6 0.2 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 ETO24036.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI WD40 PF00400.27 ETO24037.1 - 5.6e-33 111.6 14.4 2.5e-11 43.0 1.4 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO24037.1 - 4e-09 35.1 3.4 0.001 17.3 0.3 2.8 1 1 1 3 3 3 3 Nucleoporin Nup120/160 HrcA PF01628.16 ETO24038.1 - 0.0015 18.1 1.1 0.0015 18.1 0.8 2.0 1 1 1 2 2 2 1 HrcA protein C terminal domain Cep57_MT_bd PF06657.8 ETO24038.1 - 0.0023 17.8 1.4 0.0023 17.8 0.9 2.7 3 1 0 3 3 2 1 Centrosome microtubule-binding domain of Cep57 DASH_Dad4 PF08650.5 ETO24038.1 - 0.003 17.4 1.3 5.7 6.9 0.0 3.1 3 0 0 3 3 3 0 DASH complex subunit Dad4 Nup54 PF13874.1 ETO24038.1 - 0.0032 17.1 7.3 0.0032 17.1 5.0 2.4 2 1 0 2 2 2 1 Nucleoporin complex subunit 54 DUF2383 PF09537.5 ETO24038.1 - 0.0064 16.7 3.4 0.24 11.6 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF2383) DUF1465 PF07323.7 ETO24038.1 - 0.015 14.8 1.6 0.035 13.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) DUF3375 PF11855.3 ETO24038.1 - 0.02 13.6 7.6 0.065 11.9 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3375) LTXXQ PF07813.7 ETO24038.1 - 0.022 15.1 0.3 0.022 15.1 0.2 2.1 2 0 0 2 2 2 0 LTXXQ motif family protein AATF-Che1 PF13339.1 ETO24038.1 - 0.037 14.1 3.4 1 9.5 0.1 2.2 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF4455 PF14643.1 ETO24038.1 - 0.11 11.1 7.0 0.027 13.0 0.8 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4455) DUF972 PF06156.8 ETO24038.1 - 0.13 12.5 8.2 0.22 11.8 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF972) RHD PF00554.17 ETO24038.1 - 0.13 11.9 1.0 0.22 11.2 0.7 1.4 1 0 0 1 1 1 0 Rel homology domain (RHD) CCDC155 PF14662.1 ETO24038.1 - 0.25 10.8 12.2 1.8 8.1 1.6 2.2 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 Med11 PF10280.4 ETO24038.1 - 0.33 11.0 6.1 0.44 10.6 0.2 2.3 1 1 1 2 2 2 0 Mediator complex protein MscS_porin PF12795.2 ETO24038.1 - 0.36 10.0 10.5 1.4 8.1 3.2 2.3 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF1664 PF07889.7 ETO24038.1 - 0.52 10.1 10.5 6.2 6.6 0.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF2935 PF11155.3 ETO24038.1 - 0.71 9.9 3.8 0.43 10.6 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) DASH_Dam1 PF08653.5 ETO24038.1 - 1.2 8.9 4.2 20 5.0 0.3 3.3 3 0 0 3 3 3 0 DASH complex subunit Dam1 DMPK_coil PF08826.5 ETO24038.1 - 1.2 9.0 8.0 0.31 10.9 0.6 2.8 2 1 0 2 2 2 0 DMPK coiled coil domain like Baculo_PEP_C PF04513.7 ETO24038.1 - 1.6 8.5 5.7 10 5.9 0.1 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_DNA_bd PF12329.3 ETO24038.1 - 2.5 7.9 12.1 2 8.2 0.2 2.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding TMPIT PF07851.8 ETO24038.1 - 3.2 6.7 6.6 5.3 6.0 0.2 2.0 2 0 0 2 2 2 0 TMPIT-like protein Mnd1 PF03962.10 ETO24038.1 - 3.8 7.1 10.3 2.8 7.5 1.3 2.3 2 1 0 2 2 2 0 Mnd1 family AKNA PF12443.3 ETO24038.1 - 4.1 7.4 9.3 4 7.5 0.8 3.0 2 1 1 3 3 3 0 AT-hook-containing transcription factor Uds1 PF15456.1 ETO24038.1 - 4.2 7.3 8.9 3.6 7.5 1.1 3.0 1 1 2 3 3 3 0 Up-regulated During Septation Vps51 PF08700.6 ETO24038.1 - 5 7.0 7.7 2.3 8.1 0.1 3.0 3 0 0 3 3 3 0 Vps51/Vps67 Exonuc_VII_L PF02601.10 ETO24038.1 - 5.9 5.9 9.6 23 4.0 6.6 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit DASH_Dad2 PF08654.5 ETO24038.1 - 7.3 6.6 10.7 11 6.0 0.1 3.1 3 0 0 3 3 3 0 DASH complex subunit Dad2 CorA PF01544.13 ETO24038.1 - 8.2 5.3 7.8 2.6 7.0 1.7 2.2 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein YlqD PF11068.3 ETO24038.1 - 8.4 6.4 12.9 2 8.4 1.6 2.2 2 0 0 2 2 2 0 YlqD protein bZIP_1 PF00170.16 ETO24038.1 - 9 6.3 17.0 14 5.6 4.8 3.1 3 0 0 3 3 3 0 bZIP transcription factor Herpes_capsid PF06112.6 ETO24039.1 - 0.62 10.1 8.2 0.93 9.5 5.7 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein UCH PF00443.24 ETO24040.1 - 1.3e-06 27.7 0.1 1.3e-06 27.7 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Daxx PF03344.10 ETO24040.1 - 0.0016 17.0 12.4 0.0018 16.9 8.6 1.0 1 0 0 1 1 1 1 Daxx Family CDC45 PF02724.9 ETO24040.1 - 0.0038 15.3 7.5 0.0041 15.2 5.2 1.2 1 0 0 1 1 1 1 CDC45-like protein BUD22 PF09073.5 ETO24040.1 - 0.0048 16.0 10.9 0.0052 15.9 7.5 1.1 1 0 0 1 1 1 1 BUD22 Nucleoplasmin PF03066.10 ETO24040.1 - 0.0055 16.2 11.3 0.0064 16.0 7.9 1.3 1 0 0 1 1 1 1 Nucleoplasmin PBP1_TM PF14812.1 ETO24040.1 - 0.016 15.5 10.3 0.021 15.1 7.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.4 ETO24040.1 - 0.023 13.4 14.6 0.026 13.2 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) VID27 PF08553.5 ETO24040.1 - 0.024 12.8 8.2 0.023 12.9 5.7 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein RNA_pol_3_Rpc31 PF11705.3 ETO24040.1 - 0.033 14.1 17.5 0.042 13.7 12.1 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DNA_pol_phi PF04931.8 ETO24040.1 - 0.035 11.8 14.6 0.039 11.7 10.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sigma70_ner PF04546.8 ETO24040.1 - 0.037 13.6 10.7 0.046 13.3 7.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region AAR2 PF05282.6 ETO24040.1 - 0.041 12.8 3.7 0.041 12.8 2.6 1.1 1 0 0 1 1 1 0 AAR2 protein FAM176 PF14851.1 ETO24040.1 - 0.041 13.5 7.8 0.055 13.1 5.4 1.3 1 0 0 1 1 1 0 FAM176 family TRAP_alpha PF03896.11 ETO24040.1 - 0.047 12.6 5.4 0.057 12.4 3.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit BTV_NS2 PF04514.7 ETO24040.1 - 0.048 12.5 6.8 0.047 12.5 4.7 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Cytomega_UL84 PF06284.6 ETO24040.1 - 0.065 11.6 4.5 0.073 11.4 3.1 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Dala_Dala_lig_N PF01820.16 ETO24040.1 - 0.083 13.2 1.5 0.096 13.0 1.1 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Nucleo_P87 PF07267.6 ETO24040.1 - 0.085 11.5 7.6 0.095 11.3 5.2 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RP-C_C PF11800.3 ETO24040.1 - 0.088 12.5 3.0 0.088 12.4 2.1 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Ribosomal_60s PF00428.14 ETO24040.1 - 0.1 12.9 9.7 0.16 12.3 6.7 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Nop14 PF04147.7 ETO24040.1 - 0.1 10.4 14.4 0.12 10.2 10.0 1.1 1 0 0 1 1 1 0 Nop14-like family DHHW PF14286.1 ETO24040.1 - 0.18 11.1 6.0 0.2 10.9 4.2 1.1 1 0 0 1 1 1 0 DHHW protein RRN3 PF05327.6 ETO24040.1 - 0.18 9.8 6.2 0.19 9.8 4.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RNA_pol_Rpc4 PF05132.9 ETO24040.1 - 0.2 11.6 5.1 0.26 11.2 3.5 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Tim54 PF11711.3 ETO24040.1 - 0.2 10.2 8.8 0.23 10.0 6.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 BSP_II PF05432.6 ETO24040.1 - 0.2 10.8 14.0 0.25 10.5 9.7 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CPSF100_C PF13299.1 ETO24040.1 - 0.21 11.7 4.0 0.26 11.4 2.8 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal FLO_LFY PF01698.11 ETO24040.1 - 0.22 10.3 7.9 0.26 10.0 5.5 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF1510 PF07423.6 ETO24040.1 - 0.25 10.6 14.6 0.29 10.4 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pox_Ag35 PF03286.9 ETO24040.1 - 0.29 10.6 12.0 0.38 10.2 8.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF3537 PF12056.3 ETO24040.1 - 0.3 9.7 2.9 0.35 9.5 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) DUF966 PF06136.8 ETO24040.1 - 0.3 10.4 7.4 0.34 10.2 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Hid1 PF12722.2 ETO24040.1 - 0.35 8.4 4.6 0.36 8.4 3.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Vfa1 PF08432.5 ETO24040.1 - 0.4 10.6 13.9 0.54 10.2 9.6 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CobT PF06213.7 ETO24040.1 - 0.6 9.1 13.8 0.76 8.8 9.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CENP-B_dimeris PF09026.5 ETO24040.1 - 0.81 9.9 18.2 1.3 9.3 12.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TFIIA PF03153.8 ETO24040.1 - 1 9.1 13.3 1.2 8.9 9.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Myc_N PF01056.13 ETO24040.1 - 1.3 8.1 13.5 1.6 7.7 9.4 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Cellulose_synt PF03552.9 ETO24040.1 - 1.5 7.0 4.5 1.6 6.9 3.2 1.1 1 0 0 1 1 1 0 Cellulose synthase Ycf1 PF05758.7 ETO24040.1 - 1.5 6.4 7.0 1.5 6.4 4.9 1.0 1 0 0 1 1 1 0 Ycf1 DDHD PF02862.12 ETO24040.1 - 1.5 8.5 6.5 1.7 8.3 4.5 1.1 1 0 0 1 1 1 0 DDHD domain DUF789 PF05623.7 ETO24040.1 - 1.8 7.9 5.6 2.1 7.7 3.4 1.4 2 0 0 2 2 1 0 Protein of unknown function (DUF789) Sporozoite_P67 PF05642.6 ETO24040.1 - 2.2 6.0 8.8 2.5 5.8 6.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sec62 PF03839.11 ETO24040.1 - 2.2 7.6 7.2 2.6 7.4 5.0 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Peptidase_S49_N PF08496.5 ETO24040.1 - 2.3 7.9 6.9 3.2 7.5 4.8 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal YqfQ PF14181.1 ETO24040.1 - 3.6 7.5 10.9 4.8 7.2 7.6 1.2 1 0 0 1 1 1 0 YqfQ-like protein DUF2890 PF11081.3 ETO24040.1 - 8 6.4 15.9 9.7 6.1 11.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) IBR PF01485.16 ETO24042.1 - 0.011 15.6 0.5 0.89 9.4 0.0 2.2 2 0 0 2 2 2 0 IBR domain UCH PF00443.24 ETO24043.1 - 1.9e-10 40.3 0.7 2.2e-10 40.0 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF4231 PF14015.1 ETO24043.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Fer4_7 PF12838.2 ETO24043.1 - 0.036 14.4 0.2 0.076 13.4 0.1 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain PNPase PF03726.9 ETO24043.1 - 0.13 12.5 0.8 0.42 10.8 0.1 2.1 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain UCH PF00443.24 ETO24044.1 - 8.9e-07 28.2 2.1 1e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RNA_pol_3_Rpc31 PF11705.3 ETO24044.1 - 0.00034 20.6 20.4 0.00034 20.6 14.2 1.5 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.7 ETO24044.1 - 0.00094 17.2 15.0 0.00099 17.1 10.4 1.1 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 ETO24044.1 - 0.0015 17.1 12.8 0.0015 17.1 8.9 1.1 1 0 0 1 1 1 1 Daxx Family SDA1 PF05285.7 ETO24044.1 - 0.0025 17.1 13.0 0.0028 16.9 9.0 1.1 1 0 0 1 1 1 1 SDA1 Nucleo_P87 PF07267.6 ETO24044.1 - 0.007 15.1 6.3 0.0078 14.9 4.4 1.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.9 ETO24044.1 - 0.02 12.9 10.9 0.025 12.6 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Mus7 PF09462.5 ETO24044.1 - 0.034 13.0 0.6 0.034 13.0 0.4 1.1 1 0 0 1 1 1 0 Mus7/MMS22 family Myc_N PF01056.13 ETO24044.1 - 0.036 13.2 8.0 0.048 12.8 5.6 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF4045 PF13254.1 ETO24044.1 - 0.051 12.8 5.7 0.052 12.8 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) TRAP_alpha PF03896.11 ETO24044.1 - 0.088 11.7 7.3 0.12 11.3 5.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit BUD22 PF09073.5 ETO24044.1 - 0.11 11.5 19.5 0.0089 15.1 10.5 1.4 2 0 0 2 2 2 0 BUD22 DDHD PF02862.12 ETO24044.1 - 0.17 11.6 4.2 0.19 11.5 2.9 1.3 1 0 0 1 1 1 0 DDHD domain Sigma70_ner PF04546.8 ETO24044.1 - 0.17 11.4 13.5 0.3 10.6 9.3 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region RP-C_C PF11800.3 ETO24044.1 - 0.18 11.5 3.5 0.18 11.4 2.4 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF2457 PF10446.4 ETO24044.1 - 0.21 10.2 18.9 0.27 9.9 13.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CobT PF06213.7 ETO24044.1 - 0.24 10.5 16.9 0.31 10.1 11.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VID27 PF08553.5 ETO24044.1 - 0.26 9.4 14.6 0.33 9.1 10.1 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Ycf1 PF05758.7 ETO24044.1 - 0.31 8.6 9.1 0.31 8.7 6.3 1.1 1 0 0 1 1 1 0 Ycf1 RNA_polI_A34 PF08208.6 ETO24044.1 - 0.4 10.3 16.4 0.64 9.6 11.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Tim54 PF11711.3 ETO24044.1 - 0.49 8.9 10.0 0.71 8.4 7.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Hid1 PF12722.2 ETO24044.1 - 0.67 7.5 6.9 0.72 7.4 4.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.7 ETO24044.1 - 0.94 9.3 13.2 1.4 8.7 9.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Dala_Dala_lig_N PF01820.16 ETO24044.1 - 1 9.7 6.6 1.5 9.1 4.1 1.6 1 1 0 1 1 1 0 D-ala D-ala ligase N-terminus Sporozoite_P67 PF05642.6 ETO24044.1 - 4.8 4.9 10.5 6.1 4.5 7.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cellulose_synt PF03552.9 ETO24044.1 - 4.8 5.3 6.0 5.9 5.0 4.1 1.2 1 0 0 1 1 1 0 Cellulose synthase DUF2890 PF11081.3 ETO24044.1 - 6 6.8 18.7 8.7 6.3 12.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) PPP4R2 PF09184.6 ETO24044.1 - 7.2 6.0 22.9 9.9 5.6 15.8 1.2 1 0 0 1 1 1 0 PPP4R2 DUF1510 PF07423.6 ETO24044.1 - 8.8 5.6 22.5 0.64 9.3 12.4 1.4 2 0 0 2 2 1 0 Protein of unknown function (DUF1510) ubiquitin PF00240.18 ETO24045.1 - 0.0007 18.9 0.1 0.002 17.4 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin family Sec62 PF03839.11 ETO24045.1 - 0.025 13.9 1.5 0.045 13.1 1.0 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Atrophin-1 PF03154.10 ETO24045.1 - 0.22 9.6 1.8 0.27 9.3 1.2 1.0 1 0 0 1 1 1 0 Atrophin-1 family YqfQ PF14181.1 ETO24045.1 - 2.6 8.0 7.1 4.7 7.2 5.0 1.3 1 0 0 1 1 1 0 YqfQ-like protein Med15 PF09606.5 ETO24046.1 - 2.5 6.2 34.0 3.3 5.8 23.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal XPG_I PF00867.13 ETO24048.1 - 1.2e-25 89.3 0.1 2.8e-25 88.1 0.1 1.6 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 ETO24048.1 - 3.5e-08 33.2 0.0 6.2e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing XPG_N PF00752.12 ETO24048.1 - 0.00011 22.4 0.3 0.0003 21.0 0.2 1.7 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 ETO24048.1 - 0.0057 16.8 0.0 0.018 15.2 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold TFIIF_beta PF02270.10 ETO24048.1 - 0.023 14.5 1.6 0.029 14.1 0.3 2.0 2 1 0 2 2 2 0 Transcription initiation factor IIF, beta subunit ThiF PF00899.16 ETO24049.1 - 3.4e-07 30.1 0.2 2e-06 27.6 0.1 2.2 1 1 0 1 1 1 1 ThiF family DHHW PF14286.1 ETO24050.1 - 9.2 5.4 22.7 2 7.6 5.3 2.1 2 0 0 2 2 2 0 DHHW protein WD40 PF00400.27 ETO24053.1 - 1.2e-56 186.6 6.6 2.9e-13 49.1 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO24053.1 - 2.9e-06 25.8 0.4 0.018 13.3 0.2 2.9 2 1 1 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO24053.1 - 6.5e-05 21.8 1.8 0.019 13.7 0.3 2.7 1 1 2 3 3 3 2 Nup133 N terminal like B_lectin PF01453.19 ETO24053.1 - 8.3e-05 22.4 1.1 0.035 14.0 0.1 2.4 1 1 1 2 2 2 2 D-mannose binding lectin PD40 PF07676.7 ETO24053.1 - 0.0045 16.6 0.2 3.3 7.4 0.0 4.0 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO24053.1 - 0.017 14.5 0.3 0.039 13.4 0.2 1.6 1 1 0 1 1 1 0 PQQ-like domain Gmad1 PF10647.4 ETO24053.1 - 0.027 13.8 0.0 0.082 12.2 0.0 1.7 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain DUF1652 PF07865.6 ETO24053.1 - 0.03 13.9 0.0 5 6.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1652) Proteasome_A_N PF10584.4 ETO24053.1 - 0.07 12.4 2.1 5.4 6.4 0.0 3.7 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature DUF1126 PF06565.7 ETO24053.1 - 0.11 11.9 0.1 1.3 8.5 0.0 2.5 2 0 0 2 2 2 0 Repeat of unknown function (DUF1126) AAA_17 PF13207.1 ETO24054.1 - 4.7e-10 40.3 0.0 1.2e-09 38.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETO24054.1 - 9.2e-06 25.5 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETO24054.1 - 2.7e-05 24.4 0.0 7.7e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 ETO24054.1 - 0.00011 22.5 0.0 0.00014 22.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter tRNA_lig_kinase PF08303.6 ETO24054.1 - 0.00013 21.8 0.1 0.00019 21.3 0.1 1.2 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_24 PF13479.1 ETO24054.1 - 0.00029 20.4 0.1 0.0014 18.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 ETO24054.1 - 0.0009 18.2 0.0 0.0013 17.6 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_28 PF13521.1 ETO24054.1 - 0.0017 18.3 0.9 0.0051 16.7 0.6 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ETO24054.1 - 0.0024 18.0 0.0 0.0036 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 ETO24054.1 - 0.0025 17.7 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 ETO24054.1 - 0.0044 16.1 0.0 0.0074 15.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin PduV-EutP PF10662.4 ETO24054.1 - 0.0045 16.4 0.0 0.0067 15.9 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 ETO24054.1 - 0.0045 16.9 0.0 0.0067 16.4 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 ETO24054.1 - 0.0055 16.3 0.0 0.0086 15.7 0.0 1.3 1 0 0 1 1 1 1 NACHT domain FtsK_SpoIIIE PF01580.13 ETO24054.1 - 0.0058 16.1 0.0 0.0092 15.4 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family MobB PF03205.9 ETO24054.1 - 0.0065 16.1 0.1 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Parvo_NS1 PF01057.12 ETO24054.1 - 0.01 14.7 1.4 0.038 12.8 0.0 2.0 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 ATP_bind_1 PF03029.12 ETO24054.1 - 0.02 14.4 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Septin PF00735.13 ETO24054.1 - 0.022 13.7 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Septin NB-ARC PF00931.17 ETO24054.1 - 0.022 13.6 0.0 0.035 12.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_10 PF12846.2 ETO24054.1 - 0.026 13.9 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain SRP54 PF00448.17 ETO24054.1 - 0.034 13.5 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Miro PF08477.8 ETO24054.1 - 0.037 14.5 0.0 0.059 13.8 0.0 1.5 1 1 0 1 1 1 0 Miro-like protein AAA PF00004.24 ETO24054.1 - 0.044 13.9 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 ETO24054.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Viral_helicase1 PF01443.13 ETO24054.1 - 0.06 12.8 0.0 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TrwB_AAD_bind PF10412.4 ETO24054.1 - 0.074 11.6 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain GTP_EFTU PF00009.22 ETO24054.1 - 0.075 12.4 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF258 PF03193.11 ETO24054.1 - 0.079 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF87 PF01935.12 ETO24054.1 - 0.087 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_29 PF13555.1 ETO24054.1 - 0.092 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhoH PF02562.11 ETO24054.1 - 0.094 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.1 ETO24054.1 - 0.1 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 ETO24054.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 ETO24054.1 - 0.13 12.3 0.6 0.2 11.8 0.1 1.7 2 1 0 2 2 1 0 RNA helicase Sigma54_DBD PF04552.8 ETO24055.1 - 0.079 12.4 2.8 0.054 12.9 0.8 1.6 1 1 0 1 1 1 0 Sigma-54, DNA binding domain Peptidase_C58 PF03543.9 ETO24055.1 - 0.11 12.0 2.1 0.12 11.8 1.5 1.1 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen UCH PF00443.24 ETO24055.1 - 0.21 10.6 1.5 0.24 10.4 1.1 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase IncFII_repA PF02387.10 ETO24055.1 - 0.24 10.5 4.3 0.28 10.3 3.0 1.1 1 0 0 1 1 1 0 IncFII RepA protein family Casc1 PF12366.3 ETO24055.1 - 0.35 10.3 3.1 0.41 10.0 2.2 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 Ndc1_Nup PF09531.5 ETO24055.1 - 0.59 8.4 2.3 0.62 8.4 1.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MAS20 PF02064.10 ETO24055.1 - 0.96 9.3 4.0 1.4 8.8 2.8 1.2 1 0 0 1 1 1 0 MAS20 protein import receptor FH2 PF02181.18 ETO24056.1 - 3e-79 266.5 9.3 3.3e-79 266.4 6.5 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain Baculo_PEP_C PF04513.7 ETO24056.1 - 0.0085 15.9 1.0 0.019 14.7 0.2 1.9 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 ETO24056.1 - 0.04 13.0 0.2 0.061 12.4 0.1 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 ETO24056.1 - 0.4 10.9 4.8 4.7 7.5 0.1 3.5 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Nop14 PF04147.7 ETO24057.1 - 0.0014 16.6 10.4 0.0014 16.6 7.2 2.1 2 0 0 2 2 2 1 Nop14-like family CHAT PF12770.2 ETO24057.1 - 0.021 13.9 0.3 1.5 7.8 0.0 2.5 1 1 1 2 2 2 0 CHAT domain YL1 PF05764.8 ETO24057.1 - 6.2 6.3 17.4 0.67 9.5 5.5 2.5 2 0 0 2 2 2 0 YL1 nuclear protein NOA36 PF06524.7 ETO24057.1 - 6.4 5.9 34.8 0.037 13.2 10.0 3.2 3 0 0 3 3 3 0 NOA36 protein Sigma70_ner PF04546.8 ETO24057.1 - 9.6 5.7 21.8 0.42 10.2 6.4 2.8 3 0 0 3 3 3 0 Sigma-70, non-essential region Adaptin_N PF01602.15 ETO24058.1 - 0.00044 18.6 0.7 0.00053 18.4 0.5 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Proteasom_PSMB PF10508.4 ETO24058.1 - 0.0069 14.7 0.1 0.0088 14.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit Arm PF00514.18 ETO24058.1 - 0.12 12.2 0.2 3.5 7.5 0.0 2.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat SR-25 PF10500.4 ETO24059.1 - 0.46 9.9 12.7 0.83 9.0 8.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CD36 PF01130.16 ETO24060.1 - 1.5e-13 49.8 0.8 1e-12 47.1 0.5 2.0 1 1 0 1 1 1 1 CD36 family WD40 PF00400.27 ETO24061.1 - 1.2e-14 53.4 5.2 5.5e-06 26.0 0.1 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat Myelin_PLP PF01275.14 ETO24061.1 - 0.017 14.4 0.0 0.022 14.1 0.0 1.1 1 0 0 1 1 1 0 Myelin proteolipid protein (PLP or lipophilin) IKI3 PF04762.7 ETO24061.1 - 0.029 12.2 0.1 0.038 11.8 0.1 1.3 1 0 0 1 1 1 0 IKI3 family Proteasome_A_N PF10584.4 ETO24061.1 - 0.033 13.4 0.3 0.64 9.3 0.0 3.0 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature CDC45 PF02724.9 ETO24062.1 - 4 5.3 10.1 0.46 8.4 1.8 2.1 2 0 0 2 2 2 0 CDC45-like protein WD40 PF00400.27 ETO24063.1 - 0.00012 21.7 0.2 1 9.3 0.0 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF1237 PF06824.6 ETO24063.1 - 0.0011 17.6 0.1 0.0017 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) DivIVA PF05103.8 ETO24064.1 - 0.039 13.9 4.3 0.75 9.8 0.3 2.3 2 0 0 2 2 2 0 DivIVA protein DUF904 PF06005.7 ETO24064.1 - 0.053 13.8 2.7 0.27 11.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Pneumovirus_M2 PF06436.6 ETO24064.1 - 0.095 11.9 0.2 0.095 11.9 0.1 2.6 3 0 0 3 3 3 0 Pneumovirus matrix protein 2 (M2) Reo_sigmaC PF04582.7 ETO24064.1 - 1.5 7.9 6.5 0.26 10.4 0.6 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein HeH PF12949.2 ETO24065.1 - 0.006 16.0 0.1 0.011 15.2 0.1 1.4 1 0 0 1 1 1 1 HeH/LEM domain FANCI_HD1 PF14679.1 ETO24065.1 - 0.052 13.2 0.2 0.1 12.3 0.2 1.6 1 0 0 1 1 1 0 FANCI helical domain 1 Voltage_CLC PF00654.15 ETO24066.1 - 0.0011 18.0 4.9 0.014 14.4 4.1 1.9 1 1 1 2 2 2 1 Voltage gated chloride channel DUF3112 PF11309.3 ETO24066.1 - 0.014 15.1 6.0 0.13 12.0 1.7 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3112) DUF2975 PF11188.3 ETO24066.1 - 0.024 14.3 10.1 0.035 13.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) UPF0104 PF03706.8 ETO24066.1 - 0.032 13.5 10.1 0.015 14.6 2.6 2.2 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0104) Oxidored_q3 PF00499.15 ETO24066.1 - 0.04 13.6 7.3 0.13 12.0 0.4 2.6 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 O-antigen_lig PF13425.1 ETO24066.1 - 0.066 13.1 15.6 0.88 9.5 0.1 3.3 2 1 1 3 3 3 0 O-antigen ligase like membrane protein Sulfate_transp PF00916.15 ETO24066.1 - 0.07 12.1 3.8 0.093 11.7 0.3 2.1 2 0 0 2 2 2 0 Sulfate transporter family NfeD PF01957.13 ETO24066.1 - 0.09 12.9 1.8 0.28 11.3 0.1 2.1 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding Wzy_C PF04932.10 ETO24066.1 - 0.12 12.1 7.5 0.059 13.1 1.4 2.6 3 0 0 3 3 3 0 O-Antigen ligase OSTbeta PF15048.1 ETO24066.1 - 0.4 10.7 6.8 0.22 11.5 1.1 2.4 1 1 1 2 2 2 0 Organic solute transporter subunit beta protein FtsX PF02687.16 ETO24066.1 - 0.43 10.3 9.8 0.12 12.1 0.3 2.5 2 0 0 2 2 2 0 FtsX-like permease family DUF4131 PF13567.1 ETO24066.1 - 0.58 9.5 7.6 0.11 11.9 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF912 PF06024.7 ETO24066.1 - 0.73 9.9 9.2 1.1 9.3 0.3 3.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ABC2_membrane_3 PF12698.2 ETO24066.1 - 0.87 8.5 10.5 3.1 6.7 4.4 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein ETRAMP PF09716.5 ETO24066.1 - 0.96 9.4 10.1 0.14 12.1 0.4 2.8 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) 2TM PF13239.1 ETO24066.1 - 4.4 7.4 14.0 0.48 10.5 2.9 3.0 2 1 0 2 2 2 0 2TM domain Aldedh PF00171.17 ETO24069.1 - 1.9e-54 184.7 0.0 2.3e-54 184.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ins_allergen_rp PF06757.8 ETO24069.1 - 0.061 12.7 1.6 2.2 7.7 0.1 2.5 2 1 1 3 3 3 0 Insect allergen related repeat, nitrile-specifier detoxification Trans_reg_C PF00486.23 ETO24069.1 - 0.097 12.6 0.0 0.88 9.5 0.0 2.4 3 1 0 3 3 3 0 Transcriptional regulatory protein, C terminal CC2D2AN-C2 PF15625.1 ETO24070.1 - 0.0027 17.2 0.0 0.0063 16.0 0.0 1.6 1 0 0 1 1 1 1 CC2D2A N-terminal C2 domain DUF1764 PF08576.5 ETO24071.1 - 0.044 14.5 0.8 0.079 13.7 0.6 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) GPCR_chapero_1 PF11904.3 ETO24072.1 - 1.4e-32 113.0 13.4 1.7e-21 76.6 3.2 2.3 2 0 0 2 2 2 2 GPCR-chaperone FLO_LFY PF01698.11 ETO24072.1 - 4.8 5.9 13.1 1.2 7.8 4.2 2.1 2 0 0 2 2 2 0 Floricaula / Leafy protein LMBR1 PF04791.11 ETO24072.1 - 5.9 5.3 9.7 2e+02 0.2 6.7 2.0 1 1 0 1 1 1 0 LMBR1-like membrane protein Ank_2 PF12796.2 ETO24073.1 - 9.6e-08 32.2 0.0 2.4e-06 27.8 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO24073.1 - 2e-05 24.6 0.2 0.016 15.4 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 ETO24073.1 - 4.2e-05 23.1 0.1 0.0054 16.4 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 ETO24073.1 - 4.3e-05 23.8 0.0 0.0022 18.4 0.0 2.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Nop14 PF04147.7 ETO24073.1 - 0.0034 15.4 1.6 0.0053 14.7 1.1 1.2 1 0 0 1 1 1 1 Nop14-like family SMN PF06003.7 ETO24073.1 - 0.063 12.3 0.2 0.085 11.9 0.1 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Ank_3 PF13606.1 ETO24073.1 - 0.11 12.7 0.2 47 4.6 0.0 3.7 4 0 0 4 4 4 0 Ankyrin repeat DNA_pol_phi PF04931.8 ETO24073.1 - 0.65 7.6 5.6 0.97 7.1 3.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi RNA_polI_A34 PF08208.6 ETO24073.1 - 0.69 9.5 6.4 1 8.9 4.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Cupin_8 PF13621.1 ETO24074.1 - 1.1e-30 106.9 0.6 1.1e-30 106.9 0.4 1.6 2 0 0 2 2 2 1 Cupin-like domain RRF_GI PF12614.3 ETO24074.1 - 0.12 12.1 0.1 0.34 10.7 0.0 1.7 2 0 0 2 2 2 0 Ribosome recycling factor TLD PF07534.11 ETO24075.1 - 1.1e-29 103.1 0.4 2.3e-29 102.1 0.2 1.5 1 0 0 1 1 1 1 TLD GRAM PF02893.15 ETO24075.1 - 0.045 13.2 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 GRAM domain V-set PF07686.12 ETO24075.1 - 0.27 11.1 3.5 1.3 8.9 0.4 2.6 2 0 0 2 2 2 0 Immunoglobulin V-set domain DUF4160 PF13711.1 ETO24075.1 - 3.6 7.4 6.6 10 6.0 0.2 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4160) WD40 PF00400.27 ETO24077.1 - 3.2e-06 26.7 5.3 0.92 9.4 0.1 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat FimP PF09766.4 ETO24077.1 - 0.0036 16.4 5.4 0.0061 15.6 3.8 1.3 1 0 0 1 1 1 1 Fms-interacting protein adh_short PF00106.20 ETO24078.1 - 1.5e-23 83.5 0.0 2.2e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETO24078.1 - 7.3e-13 48.5 0.0 1.1e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETO24078.1 - 4.2e-12 46.3 0.0 5.4e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase zf-CCCH PF00642.19 ETO24079.1 - 3.4e-05 23.4 4.8 3.4e-05 23.4 3.3 2.2 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Kelch_1 PF01344.20 ETO24080.1 - 1.6e-13 49.9 2.0 1.1e-07 31.2 0.2 4.9 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 ETO24080.1 - 8.8e-09 35.1 2.8 0.0024 17.9 0.2 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO24080.1 - 6.3e-06 26.0 0.1 0.0038 17.1 0.1 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 ETO24080.1 - 9.4e-05 22.4 2.3 0.047 13.8 0.0 4.0 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO24080.1 - 0.00054 19.6 1.1 0.12 12.1 0.1 4.0 4 0 0 4 4 4 1 Kelch motif SieB PF14163.1 ETO24080.1 - 0.022 14.3 0.8 0.053 13.1 0.5 1.7 1 0 0 1 1 1 0 Superinfection exclusion protein B Kelch_4 PF13418.1 ETO24080.1 - 0.024 14.4 1.7 1 9.2 0.1 3.9 5 0 0 5 5 5 0 Galactose oxidase, central domain WD40 PF00400.27 ETO24082.1 - 4e-47 156.4 22.2 3.3e-10 39.4 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO24082.1 - 7.8e-09 35.5 0.1 0.0027 17.4 0.0 2.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO24082.1 - 3.1e-06 25.7 0.7 0.00031 19.1 0.0 2.1 1 1 1 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.7 ETO24082.1 - 0.0007 19.2 1.8 1.2 8.8 0.0 3.9 5 1 1 6 6 6 2 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.9 ETO24082.1 - 0.0078 15.0 0.3 0.025 13.4 0.2 1.7 1 1 1 2 2 2 1 Coatomer WD associated region DPPIV_N PF00930.16 ETO24082.1 - 0.012 14.1 0.2 0.46 9.0 0.0 2.9 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PQQ_2 PF13360.1 ETO24082.1 - 0.026 14.0 0.0 2.1 7.7 0.0 2.7 1 1 2 3 3 3 0 PQQ-like domain Lactonase PF10282.4 ETO24082.1 - 0.067 12.2 0.1 0.54 9.2 0.1 2.2 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller Hira PF07569.6 ETO24082.1 - 0.083 12.0 0.2 0.72 9.0 0.0 2.4 2 1 1 3 3 3 0 TUP1-like enhancer of split Proteasome_A_N PF10584.4 ETO24082.1 - 0.44 9.9 2.6 1.8 7.9 0.1 2.8 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature SAM_2 PF07647.12 ETO24083.1 - 4.1e-09 36.1 0.6 1.8e-08 34.0 0.1 2.4 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO24083.1 - 2.2e-06 27.7 0.6 1e-05 25.6 0.2 2.4 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) EF-hand_8 PF13833.1 ETO24083.1 - 6.5e-06 25.6 1.0 6.5e-06 25.6 0.7 2.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO24083.1 - 6.3e-05 21.9 0.6 6.3e-05 21.9 0.4 3.1 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 ETO24083.1 - 0.00034 20.2 0.9 0.0022 17.7 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.1 ETO24083.1 - 0.0029 17.7 5.2 0.0036 17.4 0.4 3.0 3 1 0 3 3 3 1 EF-hand domain pair PqqD PF05402.7 ETO24083.1 - 0.045 13.7 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) EutB PF06751.6 ETO24083.1 - 0.069 11.4 0.2 0.091 11.0 0.1 1.1 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) DnaG_DnaB_bind PF08278.6 ETO24083.1 - 0.26 11.4 2.5 0.54 10.4 0.1 2.4 2 1 0 2 2 2 0 DNA primase DnaG DnaB-binding EF-hand_5 PF13202.1 ETO24083.1 - 0.37 10.2 2.2 0.57 9.6 0.0 2.6 3 0 0 3 3 3 0 EF hand DUF1456 PF07308.8 ETO24083.1 - 0.44 10.6 6.1 3.4 7.7 0.0 3.7 4 1 0 4 4 4 0 Protein of unknown function (DUF1456) EF-hand_10 PF14788.1 ETO24083.1 - 0.92 9.2 4.6 0.32 10.6 0.7 2.2 2 0 0 2 2 2 0 EF hand Sec62 PF03839.11 ETO24084.1 - 2.5 7.4 9.3 3.7 6.9 6.5 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF2502 PF10697.4 ETO24084.1 - 7.6 6.7 11.4 3.8 7.6 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2502) DUF3936 PF13072.1 ETO24085.1 - 0.064 12.7 0.3 0.33 10.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3936) OATP PF03137.15 ETO24086.1 - 0.029 12.4 0.1 0.039 12.0 0.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Aspzincin_M35 PF14521.1 ETO24087.1 - 0.0048 17.4 1.0 0.0094 16.4 0.5 1.5 1 1 1 2 2 2 1 Lysine-specific metallo-endopeptidase adh_short PF00106.20 ETO24088.1 - 8.3e-29 100.6 0.0 8e-15 55.1 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 ETO24088.1 - 7e-11 42.1 0.0 3.3e-06 26.8 0.0 2.1 1 1 1 2 2 2 2 KR domain adh_short_C2 PF13561.1 ETO24088.1 - 1.7e-09 37.7 2.2 6.5e-08 32.6 1.5 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETO24088.1 - 9.1e-05 22.0 0.1 0.00096 18.6 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETO24088.1 - 0.00057 19.9 0.0 0.0015 18.5 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 ETO24088.1 - 0.0009 18.0 1.2 0.0022 16.7 0.1 1.8 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Flavodoxin_5 PF12724.2 ETO24088.1 - 0.037 14.0 2.4 0.091 12.7 1.3 1.8 1 1 1 2 2 2 0 Flavodoxin domain Eno-Rase_NADH_b PF12242.3 ETO24088.1 - 0.039 13.7 0.2 0.12 12.1 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PDGF_N PF04692.8 ETO24088.1 - 0.63 10.5 0.0 0.63 10.5 0.0 2.7 2 1 1 3 3 3 0 Platelet-derived growth factor, N terminal region Kinesin-relat_1 PF12711.2 ETO24090.1 - 0.018 15.4 16.7 0.023 15.0 3.0 3.2 3 1 0 3 3 3 0 Kinesin motor RPEL PF02755.10 ETO24090.1 - 0.052 12.9 6.4 0.46 9.8 0.1 3.1 3 0 0 3 3 3 0 RPEL repeat DUF1192 PF06698.6 ETO24090.1 - 0.089 12.6 3.7 1.6 8.6 0.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Lzipper-MIP1 PF14389.1 ETO24090.1 - 0.5 10.5 12.0 1.6 8.9 1.3 3.4 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DUF4140 PF13600.1 ETO24090.1 - 5.5 7.4 8.3 1.3 9.5 0.3 3.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) RRM_6 PF14259.1 ETO24091.1 - 7.3e-11 41.9 0.0 1.8e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO24091.1 - 5.9e-10 38.6 0.1 1.6e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO24091.1 - 4.5e-05 23.2 0.0 8.1e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.9 ETO24091.1 - 0.013 13.5 9.5 0.015 13.3 6.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Suf PF05843.9 ETO24091.1 - 0.087 12.5 13.0 0.12 12.0 9.0 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Utp14 PF04615.8 ETO24091.1 - 0.93 7.5 23.3 1.1 7.3 16.1 1.0 1 0 0 1 1 1 0 Utp14 protein Menin PF05053.8 ETO24091.1 - 2.1 6.4 12.3 2.6 6.0 8.5 1.1 1 0 0 1 1 1 0 Menin DUF605 PF04652.11 ETO24091.1 - 2.7 7.3 23.2 3.4 6.9 16.1 1.1 1 0 0 1 1 1 0 Vta1 like DUF1675 PF07897.6 ETO24091.1 - 3.2 7.5 18.6 4.3 7.1 12.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DHHW PF14286.1 ETO24091.1 - 4.5 6.4 14.1 2.6 7.2 8.3 1.6 1 1 0 1 1 1 0 DHHW protein FBPase PF00316.15 ETO24092.1 - 3e-34 118.2 0.0 7.8e-34 116.9 0.0 1.6 1 1 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 ETO24092.1 - 0.0079 15.5 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family Vfa1 PF08432.5 ETO24094.1 - 0.016 15.2 4.8 0.027 14.4 3.3 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Caldesmon PF02029.10 ETO24094.1 - 0.047 12.1 7.3 0.064 11.6 5.1 1.1 1 0 0 1 1 1 0 Caldesmon DUF2786 PF10979.3 ETO24094.1 - 0.15 11.8 0.2 0.24 11.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) Tfb4 PF03850.9 ETO24094.1 - 0.53 9.5 5.3 0.75 9.0 3.7 1.2 1 0 0 1 1 1 0 Transcription factor Tfb4 Serinc PF03348.10 ETO24094.1 - 0.76 8.4 2.4 2.3 6.8 1.6 1.7 1 1 0 1 1 1 0 Serine incorporator (Serinc) DUF4220 PF13968.1 ETO24094.1 - 5.4 6.0 5.9 7.7 5.5 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DUF1675 PF07897.6 ETO24095.1 - 1.9 8.2 11.4 2.4 7.9 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Mitofilin PF09731.4 ETO24095.1 - 6.2 5.3 18.7 8 4.9 12.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SRP-alpha_N PF04086.8 ETO24095.1 - 6.3 6.0 14.1 7.6 5.8 9.8 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF775 PF05603.7 ETO24095.1 - 7.7 5.9 15.4 0.11 11.9 3.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF775) LRR_6 PF13516.1 ETO24097.1 - 0.066 13.3 7.4 1.2 9.4 0.1 5.1 5 1 0 5 5 5 0 Leucine Rich repeat Kelch_1 PF01344.20 ETO24099.1 - 8.1e-09 34.8 5.2 0.0014 18.1 0.1 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO24099.1 - 1.1e-06 28.4 0.4 0.26 11.2 0.0 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 ETO24099.1 - 1.1e-06 28.5 8.4 0.095 12.9 0.1 4.7 4 1 1 5 5 5 3 Kelch motif Kelch_3 PF13415.1 ETO24099.1 - 3.2e-06 27.1 1.7 0.0068 16.5 0.0 4.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO24099.1 - 0.00015 21.3 6.0 0.13 12.0 0.2 4.5 4 1 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO24099.1 - 0.0032 17.1 3.9 0.54 10.0 0.0 3.7 3 0 0 3 3 3 1 Galactose oxidase, central domain WD40 PF00400.27 ETO24102.1 - 3.4e-14 52.0 10.1 1.2e-05 24.9 1.1 3.9 3 1 0 3 3 3 3 WD domain, G-beta repeat Rsm1 PF08600.5 ETO24102.1 - 0.072 12.9 0.1 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Rsm1-like MIP-T3 PF10243.4 ETO24103.1 - 1.6e-05 23.5 5.3 2.2e-05 23.1 3.6 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Ycf1 PF05758.7 ETO24103.1 - 6.2e-05 20.9 2.8 7.6e-05 20.6 1.9 1.0 1 0 0 1 1 1 1 Ycf1 Nucleoplasmin PF03066.10 ETO24103.1 - 0.019 14.4 6.5 0.2 11.1 2.9 2.2 2 0 0 2 2 2 0 Nucleoplasmin Gti1_Pac2 PF09729.4 ETO24103.1 - 0.025 14.4 10.4 0.043 13.6 1.6 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family NPR3 PF03666.8 ETO24103.1 - 0.029 12.9 7.0 0.13 10.7 0.0 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 SHR3_chaperone PF08229.6 ETO24103.1 - 0.035 13.0 0.4 0.035 13.0 0.3 2.5 2 1 1 3 3 3 0 ER membrane protein SH3 Folate_carrier PF01770.13 ETO24103.1 - 0.039 12.4 3.1 0.69 8.3 0.3 2.1 2 0 0 2 2 2 0 Reduced folate carrier Zip PF02535.17 ETO24103.1 - 0.046 12.7 1.2 0.079 11.9 0.8 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter POX PF07526.6 ETO24103.1 - 0.056 13.6 5.0 1.4 9.1 0.1 2.1 2 0 0 2 2 2 0 Associated with HOX Sigma70_ner PF04546.8 ETO24103.1 - 0.087 12.4 7.7 0.22 11.1 1.4 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region RasGEF_N PF00618.15 ETO24103.1 - 0.14 12.2 3.4 0.18 11.9 0.6 2.1 2 0 0 2 2 2 0 RasGEF N-terminal motif PXA PF02194.10 ETO24103.1 - 0.18 11.3 4.8 0.48 9.9 0.2 2.1 2 0 0 2 2 2 0 PXA domain CDC45 PF02724.9 ETO24103.1 - 0.37 8.7 9.6 0.31 9.0 1.0 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF1510 PF07423.6 ETO24103.1 - 0.47 9.7 16.9 1.3 8.2 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) RXT2_N PF08595.6 ETO24103.1 - 0.49 10.1 10.2 0.19 11.5 0.9 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal Rhabdo_ncap PF00945.13 ETO24103.1 - 0.56 8.7 7.9 0.19 10.2 0.6 2.0 2 0 0 2 2 2 0 Rhabdovirus nucleocapsid protein RNA_pol_Rpc4 PF05132.9 ETO24103.1 - 0.66 9.9 9.4 1.5 8.7 0.4 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 AIF_C PF14721.1 ETO24103.1 - 0.67 10.2 7.1 3.6 7.8 0.8 2.1 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term NinG PF05766.7 ETO24103.1 - 0.84 9.3 13.5 2.6 7.7 1.7 2.1 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein Vfa1 PF08432.5 ETO24103.1 - 1.1 9.3 23.0 0.071 13.1 3.1 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Afi1 PF07792.7 ETO24103.1 - 1.2 9.1 9.3 4.4 7.2 0.6 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Pox_RNA_Pol_19 PF05320.7 ETO24103.1 - 1.2 8.8 7.7 0.45 10.2 0.5 2.1 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit HA2 PF04408.18 ETO24103.1 - 2.1 8.4 4.8 3 7.8 0.6 2.3 2 0 0 2 2 2 0 Helicase associated domain (HA2) DUF2098 PF09871.4 ETO24103.1 - 4.2 7.3 10.2 2.3 8.2 0.9 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) DUF3464 PF11947.3 ETO24103.1 - 4.3 6.7 7.2 14 5.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) DUF3391 PF11871.3 ETO24103.1 - 4.9 7.3 8.2 3.1 8.0 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) OSTbeta PF15048.1 ETO24103.1 - 6.1 6.9 7.9 0.89 9.6 0.3 2.2 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein DUF2956 PF11169.3 ETO24103.1 - 6.2 6.8 21.0 2.4 8.1 3.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) DUF1764 PF08576.5 ETO24103.1 - 7.1 7.4 16.4 2.8 8.7 2.9 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) CENP-B_dimeris PF09026.5 ETO24103.1 - 7.6 6.8 9.0 0.66 10.2 2.0 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain REJ PF02010.10 ETO24104.1 - 0.0045 15.3 0.1 0.075 11.3 0.0 2.1 1 1 1 2 2 2 2 REJ domain fn3 PF00041.16 ETO24104.1 - 0.01 15.9 0.2 0.069 13.2 0.0 2.6 3 1 0 3 3 3 0 Fibronectin type III domain SET PF00856.23 ETO24105.1 - 0.11 12.8 0.1 1.3 9.3 0.0 2.1 2 0 0 2 2 2 0 SET domain Ground-like PF04155.13 ETO24105.1 - 0.37 11.1 6.1 0.87 9.9 2.9 2.4 1 1 2 3 3 3 0 Ground-like domain DUF1295 PF06966.7 ETO24107.1 - 5.2e-16 58.6 10.9 7.8e-16 58.0 7.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Amidohydro_1 PF01979.15 ETO24108.1 - 1.2e-15 58.0 0.2 1.6e-15 57.6 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 ETO24108.1 - 2.3e-06 27.8 0.1 3.2e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase DJ-1_PfpI PF01965.19 ETO24108.1 - 0.055 12.9 0.5 0.1 12.0 0.3 1.6 1 1 0 1 1 1 0 DJ-1/PfpI family Amidohydro_3 PF07969.6 ETO24108.1 - 0.065 12.4 0.1 0.14 11.3 0.1 1.6 1 1 0 1 1 1 0 Amidohydrolase family Nop14 PF04147.7 ETO24109.1 - 0.091 10.6 34.6 0.12 10.3 24.0 1.0 1 0 0 1 1 1 0 Nop14-like family Utp14 PF04615.8 ETO24109.1 - 0.22 9.6 41.6 0.24 9.5 28.8 1.0 1 0 0 1 1 1 0 Utp14 protein Dsh_C PF12316.3 ETO24109.1 - 0.24 11.4 9.8 0.31 11.1 6.8 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal MIP-T3 PF10243.4 ETO24109.1 - 0.26 9.7 48.0 0.3 9.5 33.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Daxx PF03344.10 ETO24109.1 - 0.32 9.4 33.4 0.36 9.2 23.1 1.0 1 0 0 1 1 1 0 Daxx Family SAPS PF04499.10 ETO24109.1 - 7.6 5.0 18.4 8.7 4.8 12.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ApoC-I PF04691.7 ETO24110.1 - 0.049 13.3 0.4 0.094 12.4 0.3 1.4 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) Ank_2 PF12796.2 ETO24111.1 - 1.1e-09 38.4 0.0 0.00042 20.5 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO24111.1 - 2.3e-09 37.1 0.0 5e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO24111.1 - 4e-09 36.7 0.2 0.0005 20.5 0.0 3.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 ETO24111.1 - 5.8e-09 35.3 0.1 0.0025 17.5 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 ETO24111.1 - 1.5e-07 30.9 0.1 0.0047 17.0 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat mTERF PF02536.9 ETO24111.1 - 0.062 11.8 0.1 0.086 11.4 0.0 1.1 1 0 0 1 1 1 0 mTERF RE_R_Pab1 PF09522.5 ETO24111.1 - 0.07 13.0 0.1 0.14 12.0 0.0 1.6 1 1 0 1 1 1 0 R.Pab1 restriction endonuclease DUF613 PF04764.7 ETO24111.1 - 0.1 12.4 0.4 0.27 11.1 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF613) Lumazine_bd PF12870.2 ETO24112.1 - 0.079 13.0 5.4 0.063 13.3 0.8 2.2 2 0 0 2 2 2 0 Lumazine-binding domain YL1 PF05764.8 ETO24113.1 - 0.0045 16.6 2.7 0.0045 16.6 1.9 2.4 2 1 0 2 2 2 1 YL1 nuclear protein DUF4611 PF15387.1 ETO24113.1 - 0.081 13.0 15.0 0.59 10.3 1.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CD99L2 PF12301.3 ETO24113.1 - 0.24 11.0 10.3 0.12 12.0 3.6 2.5 2 0 0 2 2 2 0 CD99 antigen like protein 2 Afi1 PF07792.7 ETO24115.1 - 1.8e-13 50.7 0.0 3.2e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 ETO24115.1 - 1.5e-12 47.2 0.3 2.9e-12 46.2 0.2 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 ETO24115.1 - 0.0058 15.1 0.0 0.011 14.2 0.0 1.3 1 1 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.4 ETO24115.1 - 0.036 13.3 0.0 0.07 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) DUF2046 PF09755.4 ETO24117.1 - 0.00038 19.4 1.9 0.00039 19.3 1.3 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) bZIP_1 PF00170.16 ETO24117.1 - 0.00062 19.6 5.8 0.028 14.3 0.2 2.3 2 1 0 2 2 2 2 bZIP transcription factor Atx10homo_assoc PF09759.4 ETO24117.1 - 0.00096 18.8 1.2 0.0018 17.9 0.1 1.8 1 1 1 2 2 2 1 Spinocerebellar ataxia type 10 protein domain DUF972 PF06156.8 ETO24117.1 - 0.016 15.5 7.7 0.15 12.3 4.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) CENP-F_leu_zip PF10473.4 ETO24117.1 - 0.018 14.9 9.7 0.032 14.1 6.7 1.4 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Protein_K PF12283.3 ETO24117.1 - 0.024 14.5 1.4 0.45 10.4 0.4 2.3 2 0 0 2 2 2 0 Bacteriophage protein K Mnd1 PF03962.10 ETO24117.1 - 0.031 13.9 5.4 0.13 11.9 3.8 1.8 1 1 0 1 1 1 0 Mnd1 family DUF904 PF06005.7 ETO24117.1 - 0.043 14.0 7.7 2.3 8.5 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Kinetocho_Slk19 PF12709.2 ETO24117.1 - 0.046 13.8 6.4 0.074 13.1 0.2 2.2 1 1 1 2 2 2 0 Central kinetochore-associated CHASE3 PF05227.8 ETO24117.1 - 0.057 13.1 4.4 0.16 11.6 3.0 1.6 1 1 0 1 1 1 0 CHASE3 domain Atg14 PF10186.4 ETO24117.1 - 0.077 11.9 7.9 0.085 11.7 5.5 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF641 PF04859.7 ETO24117.1 - 0.087 12.5 0.6 0.087 12.5 0.4 1.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Cadherin_2 PF08266.7 ETO24117.1 - 0.11 12.0 0.8 0.17 11.5 0.5 1.3 1 0 0 1 1 1 0 Cadherin-like GAT PF03127.9 ETO24117.1 - 0.12 12.3 3.8 0.2 11.6 2.6 1.5 1 1 0 1 1 1 0 GAT domain HAP1_N PF04849.8 ETO24117.1 - 0.13 11.1 9.3 0.25 10.2 0.6 2.0 1 1 0 2 2 2 0 HAP1 N-terminal conserved region DUF4168 PF13767.1 ETO24117.1 - 0.22 12.1 2.6 0.3 11.7 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4168) bZIP_2 PF07716.10 ETO24117.1 - 0.22 11.3 9.5 4.2 7.2 3.2 2.5 2 1 0 2 2 2 0 Basic region leucine zipper TMF_TATA_bd PF12325.3 ETO24117.1 - 0.23 11.1 8.6 0.32 10.7 5.9 1.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding PhoQ_Sensor PF08918.5 ETO24117.1 - 0.24 10.9 1.6 2.3 7.6 0.0 2.0 1 1 1 2 2 2 0 PhoQ Sensor BPL_N PF09825.4 ETO24117.1 - 0.26 10.0 2.3 0.27 9.9 1.6 1.0 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Seryl_tRNA_N PF02403.17 ETO24117.1 - 0.52 10.3 6.4 0.76 9.8 4.4 1.3 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DivIVA PF05103.8 ETO24117.1 - 0.84 9.6 7.3 5.1 7.1 0.9 2.2 1 1 1 2 2 2 0 DivIVA protein NYD-SP28_assoc PF14775.1 ETO24117.1 - 1.6 8.4 5.3 0.44 10.2 1.1 2.0 2 1 0 2 2 2 0 Sperm tail C-terminal domain Cep57_CLD_2 PF14197.1 ETO24117.1 - 1.7 8.6 8.1 7 6.6 5.6 1.9 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 THOC7 PF05615.8 ETO24117.1 - 1.8 8.8 9.0 2 8.6 0.5 2.0 1 1 1 2 2 2 0 Tho complex subunit 7 IncA PF04156.9 ETO24117.1 - 6 6.4 9.9 9.1 5.8 6.1 1.5 1 1 0 1 1 1 0 IncA protein Exo_endo_phos PF03372.18 ETO24118.1 - 1.5e-17 64.3 0.1 2.4e-17 63.6 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF504 PF04457.7 ETO24118.1 - 2.3e-05 24.4 0.5 5.4e-05 23.2 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF504) NTP_transf_2 PF01909.18 ETO24118.1 - 0.0088 16.3 0.0 0.032 14.5 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF4196 PF13846.1 ETO24119.1 - 0.003 17.8 9.7 0.0043 17.3 6.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4196) DNase_NucA_NucB PF14040.1 ETO24119.1 - 0.041 14.0 2.0 0.13 12.3 1.1 2.0 1 1 0 1 1 1 0 Deoxyribonuclease NucA/NucB PGA2 PF07543.7 ETO24119.1 - 0.2 11.4 6.0 0.28 10.9 4.2 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 TFIIF_alpha PF05793.7 ETO24119.1 - 0.43 8.8 18.1 0.55 8.5 12.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Herpes_PAP PF03325.8 ETO24119.1 - 1.4 8.4 9.7 1.5 8.3 6.7 1.1 1 0 0 1 1 1 0 Herpesvirus polymerase accessory protein NPR3 PF03666.8 ETO24119.1 - 3.6 6.0 8.3 4 5.8 5.8 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FLO_LFY PF01698.11 ETO24119.1 - 4.4 6.0 7.3 5 5.8 5.1 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein MRI PF15325.1 ETO24119.1 - 5 8.1 10.7 6.6 7.7 7.0 1.6 1 1 0 1 1 1 0 Modulator of retrovirus infection RabGAP-TBC PF00566.13 ETO24122.1 - 2.4e-35 121.9 1.7 1e-34 119.9 0.8 3.5 4 0 0 4 4 4 2 Rab-GTPase-TBC domain DsrC PF04358.8 ETO24124.1 - 0.044 14.0 0.2 0.086 13.0 0.2 1.5 1 0 0 1 1 1 0 DsrC like protein Secretin_N_2 PF07655.8 ETO24124.1 - 0.53 10.6 17.0 1.3 9.4 11.8 1.7 1 0 0 1 1 1 0 Secretin N-terminal domain zf-UBP PF02148.14 ETO24126.1 - 5.4e-14 52.0 0.0 1.2e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein T4_baseplate PF12322.3 ETO24126.1 - 0.052 12.8 0.0 0.073 12.3 0.0 1.2 1 0 0 1 1 1 0 T4 bacteriophage base plate protein UCH PF00443.24 ETO24127.1 - 4.9e-33 114.3 1.0 6.1e-33 114.0 0.7 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO24127.1 - 1.6e-14 54.0 1.8 3.3e-13 49.7 1.2 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 ETO24127.1 - 8.7e-12 44.5 0.2 1.2e-05 25.0 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain UBA_2 PF08587.6 ETO24127.1 - 0.056 13.6 0.1 0.52 10.5 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) DUF3612 PF12268.3 ETO24127.1 - 0.084 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3612) DUF2779 PF11074.3 ETO24127.1 - 0.21 11.6 2.5 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function(DUF2779) PDEase_I PF00233.14 ETO24128.1 - 4.4e-65 219.7 12.3 4.3e-38 131.4 4.5 2.5 3 0 0 3 3 3 2 3'5'-cyclic nucleotide phosphodiesterase GATase PF00117.23 ETO24129.1 - 0.00055 19.4 0.1 0.0013 18.2 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 ETO24129.1 - 0.077 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase C26 RNase_H2-Ydr279 PF09468.5 ETO24129.1 - 1.1 8.3 14.3 1.7 7.7 9.9 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) TATR PF03430.8 ETO24129.1 - 2.8 6.4 8.1 4.3 5.8 5.6 1.3 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Dsh_C PF12316.3 ETO24129.1 - 4.8 7.2 10.6 7.5 6.6 7.4 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal WD40 PF00400.27 ETO24130.1 - 1.8e-60 198.7 31.9 3.6e-10 39.3 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO24130.1 - 4.2e-10 38.3 5.8 0.00024 19.4 0.4 4.5 2 1 2 5 5 5 4 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO24131.1 - 0.00015 22.0 0.5 0.00015 22.0 0.4 2.7 3 0 0 3 3 3 1 TRAF-type zinc finger DUF2681 PF10883.3 ETO24132.1 - 0.00054 20.1 1.5 0.081 13.1 0.2 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2681) TrbL PF04610.9 ETO24132.1 - 0.037 13.7 0.2 0.044 13.4 0.1 1.1 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein YqhR PF11085.3 ETO24132.1 - 0.066 12.7 0.5 0.089 12.3 0.1 1.4 1 1 0 1 1 1 0 Conserved membrane protein YqhR FixQ PF05545.6 ETO24132.1 - 1 9.0 5.7 1.6 8.3 3.3 1.9 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF2085 PF09858.4 ETO24134.1 - 0.041 13.9 1.5 0.25 11.4 1.0 2.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2085) DUF1691 PF07950.6 ETO24134.1 - 0.48 10.3 4.7 0.15 12.0 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1691) zf-NPL4 PF05020.10 ETO24135.1 - 0.056 13.1 0.6 0.19 11.4 0.1 2.0 2 0 0 2 2 2 0 NPL4 family, putative zinc binding region Sif PF06767.6 ETO24135.1 - 0.11 11.1 0.0 0.24 10.1 0.0 1.4 1 0 0 1 1 1 0 Sif protein BACK PF07707.10 ETO24136.1 - 7e-10 38.6 1.0 1.7e-09 37.4 0.7 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.26 ETO24136.1 - 6.2e-06 26.1 0.0 1.6e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain SAM_2 PF07647.12 ETO24137.1 - 0.00015 21.5 0.0 0.00047 19.9 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 ETO24137.1 - 0.011 15.5 0.7 0.038 13.7 0.2 2.2 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain SAM_1 PF00536.25 ETO24137.1 - 0.025 14.7 0.0 0.085 13.0 0.0 2.0 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Act-Frag_cataly PF09192.5 ETO24138.1 - 0.024 13.5 0.4 0.032 13.2 0.3 1.2 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic Reovirus_M2 PF05993.7 ETO24138.1 - 0.058 11.2 0.0 0.068 10.9 0.0 1.1 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) CcmB PF03379.8 ETO24139.1 - 0.069 12.3 0.0 0.094 11.9 0.0 1.2 1 0 0 1 1 1 0 CcmB protein DUF1609 PF07753.6 ETO24140.1 - 0.11 11.8 0.3 0.2 10.9 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1609) WD40 PF00400.27 ETO24141.1 - 0.0019 18.0 0.2 0.72 9.8 0.1 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat tRNA-synt_1e PF01406.14 ETO24142.1 - 0.016 14.3 0.0 0.023 13.8 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain EF-hand_1 PF00036.27 ETO24145.1 - 0.027 13.7 0.4 1.4 8.4 0.0 2.9 3 0 0 3 3 3 0 EF hand Fanconi_A PF03511.9 ETO24145.1 - 0.033 13.9 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 Fanconi anaemia group A protein Glyco_transf_10 PF00852.14 ETO24146.1 - 3.2e-10 39.1 1.1 8.8e-05 21.2 0.0 2.9 2 1 0 2 2 2 2 Glycosyltransferase family 10 (fucosyltransferase) MRP-L46 PF11788.3 ETO24147.1 - 0.27 11.9 0.0 0.27 11.9 0.0 3.1 1 1 0 2 2 2 0 39S mitochondrial ribosomal protein L46 G0-G1_switch_2 PF15103.1 ETO24147.1 - 3.2 8.0 0.0 3.2 8.0 0.0 3.0 3 0 0 3 3 3 0 G0/G1 switch protein 2 DUF2469 PF10611.4 ETO24148.1 - 0.15 12.4 4.4 0.55 10.6 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2469) PHTB1_C PF14728.1 ETO24148.1 - 0.24 10.1 8.5 0.3 9.8 5.9 1.2 1 0 0 1 1 1 0 PTHB1 C-terminus DUF3987 PF13148.1 ETO24148.1 - 0.72 8.3 12.6 0.28 9.7 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Cupin_8 PF13621.1 ETO24148.1 - 1 8.8 6.0 1.4 8.3 4.2 1.4 1 0 0 1 1 1 0 Cupin-like domain Birna_RdRp PF04197.7 ETO24148.1 - 1.5 6.7 12.4 1.8 6.4 8.6 1.0 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) MtrB PF05440.7 ETO24148.1 - 3.2 7.8 4.4 2 8.5 0.2 2.5 1 1 2 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF3106 PF11304.3 ETO24148.1 - 3.6 8.0 15.0 0.18 12.2 4.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) DUF1539 PF07560.6 ETO24148.1 - 4.4 7.1 8.5 0.93 9.3 1.4 2.4 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1539) CpXC PF14353.1 ETO24148.1 - 8.7 6.3 11.1 0.23 11.4 1.0 2.5 1 1 1 2 2 2 0 CpXC protein Pkinase PF00069.20 ETO24149.1 - 1.6e-55 188.0 0.2 1.6e-55 188.0 0.1 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO24149.1 - 2e-38 131.9 0.0 3.9e-38 130.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO24149.1 - 3.2e-05 23.0 0.1 7e-05 21.9 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETO24149.1 - 0.00014 20.9 0.0 0.0003 19.8 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETO24149.1 - 0.00021 21.0 0.0 0.00039 20.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family BAF1_ABF1 PF04684.8 ETO24149.1 - 0.0031 16.4 14.8 0.0056 15.5 10.2 1.3 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Choline_kinase PF01633.15 ETO24149.1 - 0.0032 17.0 0.1 0.0032 17.0 0.1 2.3 2 0 0 2 2 2 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 ETO24149.1 - 0.051 12.9 1.7 0.18 11.1 0.0 2.5 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL DUF1345 PF07077.6 ETO24149.1 - 0.051 13.0 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) Macoilin PF09726.4 ETO24149.1 - 0.33 9.1 8.9 0.47 8.6 6.2 1.1 1 0 0 1 1 1 0 Transmembrane protein CPSF73-100_C PF11718.3 ETO24149.1 - 0.58 9.4 8.3 1.1 8.5 5.8 1.4 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Na_trans_assoc PF06512.8 ETO24149.1 - 5 7.0 11.1 0.94 9.4 5.1 1.6 2 0 0 2 2 2 0 Sodium ion transport-associated cNMP_binding PF00027.24 ETO24150.1 - 4.1e-23 81.0 0.0 5.4e-23 80.6 0.0 1.2 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain tRNA_int_endo_N PF02778.9 ETO24150.1 - 0.045 13.2 0.1 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain Pkinase PF00069.20 ETO24151.1 - 4.6e-07 29.2 0.0 7.4e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 ETO24152.1 - 6.6e-43 146.7 0.2 8.5e-42 143.0 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO24152.1 - 1.7e-17 63.3 0.1 1.4e-08 34.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 ETO24152.1 - 0.0022 17.0 0.1 0.38 9.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Seadorna_VP7 PF07387.6 ETO24152.1 - 0.046 12.5 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RhoGAP PF00620.22 ETO24152.1 - 0.1 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 RhoGAP domain PH PF00169.24 ETO24153.1 - 0.00034 20.7 1.8 0.00085 19.4 0.0 2.3 2 1 0 2 2 2 1 PH domain IncA PF04156.9 ETO24153.1 - 0.0013 18.3 10.7 0.0013 18.3 7.4 1.7 2 0 0 2 2 2 1 IncA protein PH_6 PF15406.1 ETO24153.1 - 0.044 13.8 0.0 0.14 12.1 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain DUF1664 PF07889.7 ETO24153.1 - 0.88 9.3 6.2 21 4.9 2.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.6 ETO24153.1 - 4.8 7.6 13.5 1 9.8 4.3 3.2 2 1 1 3 3 3 0 Syntaxin 6, N-terminal bZIP_1 PF00170.16 ETO24153.1 - 5.8 6.9 17.0 0.36 10.8 1.0 2.9 1 1 1 2 2 2 0 bZIP transcription factor RGS PF00615.14 ETO24154.1 - 1e-06 28.8 0.0 6.2e-06 26.3 0.0 2.1 1 1 0 1 1 1 1 Regulator of G protein signaling domain GTP_EFTU_D3 PF03143.12 ETO24155.1 - 3e-14 52.9 0.0 1.1e-13 51.1 0.0 2.0 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain Chrome_Resist PF09828.4 ETO24156.1 - 0.0031 17.7 0.0 0.0058 16.8 0.0 1.4 1 0 0 1 1 1 1 Chromate resistance exported protein 7tm_3 PF00003.17 ETO24157.1 - 1.5e-13 50.6 34.0 2.3e-13 50.0 18.8 2.8 2 1 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR Folate_carrier PF01770.13 ETO24160.1 - 0.074 11.5 0.1 0.1 11.0 0.1 1.1 1 0 0 1 1 1 0 Reduced folate carrier PMT_C PF11647.3 ETO24160.1 - 0.12 12.0 0.5 0.27 10.8 0.4 1.6 1 0 0 1 1 1 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 DUF4116 PF13475.1 ETO24160.1 - 1.6 8.3 5.0 2.4 7.7 1.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4116) HSP70 PF00012.15 ETO24161.1 - 3e-05 22.1 0.0 0.00011 20.2 0.1 1.9 2 0 0 2 2 2 1 Hsp70 protein CUE PF02845.11 ETO24162.1 - 0.14 11.7 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 CUE domain Host_attach PF10116.4 ETO24163.1 - 0.048 13.8 0.1 0.064 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein required for attachment to host cells DUF3835 PF12927.2 ETO24163.1 - 0.41 11.6 6.7 9.4 7.2 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3835) XAP5 PF04921.9 ETO24163.1 - 0.69 9.4 7.2 0.86 9.1 5.0 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator Rotamase_2 PF13145.1 ETO24163.1 - 0.86 10.2 5.3 3.7 8.1 0.5 2.1 2 0 0 2 2 2 0 PPIC-type PPIASE domain DUF4047 PF13256.1 ETO24163.1 - 2.1 8.3 9.0 14 5.6 6.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) G-alpha PF00503.15 ETO24164.1 - 4.7e-19 68.3 0.0 5.7e-19 68.0 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit AAA_17 PF13207.1 ETO24164.1 - 0.055 14.2 0.0 0.07 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain 2OG-FeII_Oxy PF03171.15 ETO24165.1 - 6.6e-15 55.2 0.1 1.5e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 ETO24165.1 - 1.1e-08 35.5 0.0 5.8e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal TauD PF02668.11 ETO24165.1 - 0.094 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family ThiF PF00899.16 ETO24166.1 - 3.2e-21 75.5 0.2 4.2e-21 75.1 0.1 1.1 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 ETO24166.1 - 0.0003 20.8 0.0 0.00039 20.5 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.1 ETO24166.1 - 0.012 14.5 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) RPEL PF02755.10 ETO24167.1 - 0.017 14.4 0.3 0.017 14.4 0.2 5.7 6 0 0 6 6 6 0 RPEL repeat Plectin PF00681.15 ETO24167.1 - 0.039 13.4 0.1 0.18 11.3 0.0 2.2 2 0 0 2 2 2 0 Plectin repeat DUF3385 PF11865.3 ETO24170.1 - 0.18 11.7 0.7 5.2 6.9 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) C2 PF00168.25 ETO24171.1 - 2.8e-05 23.8 0.0 5.7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain PDZ PF00595.19 ETO24171.1 - 0.0007 19.7 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) FYRC PF05965.9 ETO24172.1 - 4.3e-15 55.3 0.0 9.3e-15 54.2 0.0 1.6 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.9 ETO24172.1 - 1.3e-09 37.4 0.0 2.1e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 F/Y-rich N-terminus Laps PF10169.4 ETO24172.1 - 0.45 10.7 12.4 0.15 12.3 6.1 2.0 2 0 0 2 2 2 0 Learning-associated protein DUF2956 PF11169.3 ETO24172.1 - 5 7.1 9.4 92 3.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) EF-hand_1 PF00036.27 ETO24173.1 - 0.0031 16.7 0.7 1 8.7 0.0 3.2 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.1 ETO24173.1 - 0.004 17.2 3.1 1.4 9.0 0.3 2.7 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 ETO24173.1 - 0.0053 16.5 4.0 1.7 8.7 0.2 3.3 2 1 1 3 3 3 1 EF-hand domain TFR_dimer PF04253.10 ETO24173.1 - 0.025 14.1 0.1 0.045 13.3 0.0 1.5 1 1 0 1 1 1 0 Transferrin receptor-like dimerisation domain EF-hand_8 PF13833.1 ETO24173.1 - 0.027 14.0 0.9 2.4 7.8 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain pair SPC25 PF06703.6 ETO24173.1 - 0.029 13.9 3.4 0.068 12.7 2.4 1.5 1 1 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) PS_Dcarbxylase PF02666.10 ETO24174.1 - 0.054 12.7 0.0 0.078 12.2 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylserine decarboxylase SpoVAD PF07451.6 ETO24174.1 - 0.074 11.4 0.0 0.098 11.0 0.0 1.2 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) KIAA1328 PF15369.1 ETO24175.1 - 1.3 8.7 10.0 2 8.1 6.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 Macoilin PF09726.4 ETO24175.1 - 1.4 7.1 17.3 1.5 7.0 12.0 1.1 1 0 0 1 1 1 0 Transmembrane protein CDI PF02234.14 ETO24176.1 - 0.012 15.4 0.6 0.044 13.5 0.4 1.9 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor AIF_C PF14721.1 ETO24176.1 - 3.8 7.7 7.1 29 4.8 2.0 2.9 3 0 0 3 3 3 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Methyltransf_12 PF08242.7 ETO24176.1 - 5.8 7.4 7.1 0.62 10.5 1.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Neogenin_C PF06583.7 ETO24178.1 - 0.011 15.2 2.7 0.014 14.9 1.8 1.1 1 0 0 1 1 1 0 Neogenin C-terminus WD40 PF00400.27 ETO24180.1 - 5.6e-36 121.1 18.9 7.5e-09 35.1 0.2 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO24180.1 - 5e-06 24.9 1.3 0.13 10.3 0.0 3.5 2 1 2 4 4 4 3 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO24180.1 - 2.2e-05 24.7 2.0 2.2e-05 24.7 1.4 2.7 2 0 0 2 2 2 1 TRAF-type zinc finger DUF4482 PF14818.1 ETO24180.1 - 0.04 14.5 4.4 0.095 13.3 3.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) Ion_trans_2 PF07885.11 ETO24181.1 - 8.2e-15 54.2 5.8 1.4e-14 53.5 4.0 1.4 1 0 0 1 1 1 1 Ion channel EF-hand_7 PF13499.1 ETO24181.1 - 1e-08 35.2 9.1 1.7e-05 24.8 2.4 2.5 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 ETO24181.1 - 1.7e-08 33.1 8.1 4.7e-05 22.3 0.5 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 ETO24181.1 - 5.9e-07 28.8 3.7 0.0019 17.9 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 ETO24181.1 - 6.6e-05 22.0 7.3 0.0082 15.4 0.5 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 ETO24181.1 - 0.00055 19.5 5.5 0.15 11.7 0.3 2.6 1 1 1 2 2 2 2 EF-hand domain pair Ion_trans PF00520.26 ETO24181.1 - 0.0026 17.0 5.3 0.0038 16.4 3.7 1.2 1 0 0 1 1 1 1 Ion transport protein DUF2400 PF09674.5 ETO24182.1 - 0.29 10.7 9.3 0.29 10.7 3.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2400) Kinesin PF00225.18 ETO24183.1 - 1.2e-09 37.3 0.2 1.3e-09 37.2 0.2 1.0 1 0 0 1 1 1 1 Kinesin motor domain Kinesin PF00225.18 ETO24184.1 - 6.3e-27 94.1 0.0 8.1e-27 93.7 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain DUF3338 PF11819.3 ETO24185.1 - 0.033 13.6 11.0 0.065 12.6 2.7 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3338) FlaC_arch PF05377.6 ETO24185.1 - 0.2 11.5 8.8 1.2 9.1 2.3 3.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) OSR1_C PF12202.3 ETO24185.1 - 2.1 8.0 5.7 16 5.2 0.0 3.4 3 0 0 3 3 3 0 Oxidative-stress-responsive kinase 1 C terminal RRM_6 PF14259.1 ETO24186.1 - 0.0011 18.8 0.0 0.0035 17.2 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO24186.1 - 0.0058 16.4 0.0 0.017 14.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAD_synthase PF02540.12 ETO24187.1 - 2.5e-12 46.2 0.1 4.5e-12 45.3 0.0 1.5 2 0 0 2 2 2 1 NAD synthase SAM_1 PF00536.25 ETO24188.1 - 4.3e-06 26.8 0.1 8.1e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO24188.1 - 7.9e-06 25.6 0.1 1.5e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) LIM PF00412.17 ETO24188.1 - 0.0012 18.8 5.6 0.0021 18.0 3.9 1.4 1 0 0 1 1 1 1 LIM domain zf-AD PF07776.10 ETO24188.1 - 0.55 10.2 6.4 1.7 8.6 0.1 3.7 3 1 0 3 3 3 0 Zinc-finger associated domain (zf-AD) DUF4048 PF13257.1 ETO24188.1 - 1.1 8.8 20.1 2.3 7.8 13.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4048) BTV_NS2 PF04514.7 ETO24188.1 - 1.3 7.8 8.3 1.8 7.4 5.8 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 zf-HYPF PF07503.7 ETO24188.1 - 1.8 8.0 9.6 2.3 7.7 4.2 2.6 2 1 0 2 2 2 0 HypF finger G-alpha PF00503.15 ETO24189.1 - 1e-23 83.6 1.2 1.4e-23 83.2 0.9 1.1 1 0 0 1 1 1 1 G-protein alpha subunit AAA_29 PF13555.1 ETO24189.1 - 0.0087 15.5 0.2 0.036 13.5 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_14 PF13173.1 ETO24189.1 - 0.015 15.1 0.3 0.042 13.7 0.2 1.8 1 1 0 1 1 1 0 AAA domain Arf PF00025.16 ETO24189.1 - 0.023 13.9 0.1 0.05 12.8 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETO24189.1 - 0.028 14.3 0.1 0.27 11.2 0.0 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase Arch_ATPase PF01637.13 ETO24189.1 - 0.028 14.1 0.7 0.13 11.9 0.1 2.0 2 0 0 2 2 2 0 Archaeal ATPase SRPRB PF09439.5 ETO24189.1 - 0.067 12.4 0.1 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Miro PF08477.8 ETO24189.1 - 0.067 13.6 0.2 0.58 10.6 0.0 2.5 2 1 1 3 3 3 0 Miro-like protein AAA_33 PF13671.1 ETO24189.1 - 0.13 12.1 0.1 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 ETO24190.1 - 0.19 11.6 2.0 0.4 10.6 0.0 2.6 3 0 0 3 3 3 0 WD domain, G-beta repeat Mating_C PF12737.2 ETO24191.1 - 0.058 12.2 0.6 0.076 11.8 0.4 1.0 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 Peptidase_S10 PF00450.17 ETO24192.1 - 7.2e-16 58.3 0.0 2.5e-12 46.6 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase Ank_2 PF12796.2 ETO24193.1 - 2.1e-40 136.9 4.6 2.1e-17 63.2 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 ETO24193.1 - 1.8e-32 109.5 0.5 1.3e-06 27.9 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 ETO24193.1 - 5.3e-23 80.9 0.5 4.8e-06 26.9 0.0 4.5 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO24193.1 - 2.8e-22 76.5 0.7 0.0037 17.3 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 ETO24193.1 - 7.3e-20 70.5 1.0 1.8e-05 24.7 0.0 6.5 2 2 5 7 7 7 5 Ankyrin repeats (many copies) EBA-175_VI PF11556.3 ETO24193.1 - 2.1 8.4 11.6 8.4 6.5 0.8 2.8 2 1 0 2 2 2 0 Erythrocyte binding antigen 175 DUF4638 PF15472.1 ETO24194.1 - 0.043 13.4 0.3 0.055 13.0 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4638) BSP_II PF05432.6 ETO24195.1 - 2 7.6 10.4 3.6 6.7 7.2 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) UDPGP PF01704.13 ETO24198.1 - 2.4e-05 23.0 0.0 3.4e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase OAS1_C PF10421.4 ETO24199.1 - 5.6e-05 22.7 0.1 0.19 11.1 0.0 2.3 2 0 0 2 2 2 2 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus PAP_central PF04928.12 ETO24199.1 - 0.00075 18.3 0.1 0.028 13.2 0.0 2.1 2 0 0 2 2 2 2 Poly(A) polymerase central domain tRNA_NucTransf2 PF09249.6 ETO24199.1 - 0.0011 18.7 0.0 0.0028 17.5 0.0 1.6 1 0 0 1 1 1 1 tRNA nucleotidyltransferase, second domain PAP_assoc PF03828.14 ETO24199.1 - 0.0044 16.9 2.3 0.01 15.7 1.6 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase DUF3244 PF11589.3 ETO24200.1 - 0.13 12.0 0.1 0.31 10.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3244) DUF3627 PF12299.3 ETO24203.1 - 0.051 13.6 6.0 0.13 12.2 4.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3627) G-gamma PF00631.17 ETO24203.1 - 0.21 11.3 0.0 0.21 11.3 0.0 3.5 4 1 0 4 4 4 0 GGL domain Ank_2 PF12796.2 ETO24204.1 - 2.7e-34 117.3 2.4 6e-14 52.1 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETO24204.1 - 2.9e-24 83.5 0.2 8.8e-06 25.2 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.1 ETO24204.1 - 1.8e-14 52.3 0.4 0.0014 18.6 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 ETO24204.1 - 7e-14 51.5 0.1 6.8e-05 22.9 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO24204.1 - 2.4e-10 40.6 1.1 0.00045 20.6 0.0 4.4 1 1 3 5 5 5 5 Ankyrin repeats (many copies) HTH_45 PF14947.1 ETO24204.1 - 0.032 14.0 0.2 4.2 7.2 0.0 2.9 2 1 0 2 2 2 0 Winged helix-turn-helix OmpH PF03938.9 ETO24205.1 - 2.2 8.2 82.5 0.86 9.5 4.8 4.2 2 1 2 4 4 4 0 Outer membrane protein (OmpH-like) Reo_sigmaC PF04582.7 ETO24205.1 - 3 6.9 17.6 0.4 9.8 6.9 2.6 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Med28 PF11594.3 ETO24206.1 - 0.00022 21.4 3.5 0.00022 21.4 2.4 4.7 3 2 1 5 5 5 1 Mediator complex subunit 28 G-gamma PF00631.17 ETO24206.1 - 0.0037 16.9 0.7 0.6 9.9 0.1 3.4 2 0 0 2 2 2 1 GGL domain ATG16 PF08614.6 ETO24206.1 - 1 9.1 69.2 0.032 14.0 4.2 5.6 2 2 2 5 5 5 0 Autophagy protein 16 (ATG16) Lectin_N PF03954.9 ETO24206.1 - 1.5 8.2 13.6 4.2 6.7 0.8 4.0 3 1 0 3 3 3 0 Hepatic lectin, N-terminal domain SAM_2 PF07647.12 ETO24207.1 - 0.014 15.1 0.1 0.046 13.5 0.1 1.9 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) WD40 PF00400.27 ETO24210.1 - 4.6e-85 276.7 17.7 5.5e-13 48.2 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO24210.1 - 2.4e-10 40.4 0.2 0.00022 21.0 0.0 3.4 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO24210.1 - 6e-10 37.8 5.0 0.37 8.8 0.0 5.7 1 1 3 5 5 5 5 Nucleoporin Nup120/160 Resistin PF06954.6 ETO24210.1 - 1.2e-08 35.1 0.1 0.085 13.1 0.1 5.0 4 2 1 5 5 5 2 Resistin Cytochrom_D1 PF02239.11 ETO24210.1 - 1.5e-08 33.4 0.3 0.0016 16.8 0.0 3.3 1 1 2 3 3 3 3 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO24210.1 - 2.1e-05 23.4 9.9 0.31 9.7 0.1 5.7 2 1 3 6 6 6 2 Nup133 N terminal like Nbas_N PF15492.1 ETO24210.1 - 0.00054 19.1 0.8 0.99 8.4 0.0 3.9 1 1 3 5 5 5 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 ETO24210.1 - 0.0012 18.4 6.3 8.5 6.1 0.0 5.7 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO24210.1 - 0.0017 17.8 0.2 0.16 11.3 0.1 3.0 1 1 0 1 1 1 1 PQQ-like domain Proteasome_A_N PF10584.4 ETO24210.1 - 0.06 12.6 8.5 7.6 5.9 0.0 4.3 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature DHFR_2 PF06442.6 ETO24210.1 - 0.075 12.6 0.0 4.5 6.9 0.0 3.0 3 1 0 3 3 3 0 R67 dihydrofolate reductase Tyrosinase PF00264.15 ETO24212.1 - 3.1e-20 73.2 3.0 3.1e-20 73.2 2.1 1.9 2 0 0 2 2 2 1 Common central domain of tyrosinase WD40 PF00400.27 ETO24213.1 - 8.5e-79 256.8 20.5 6.1e-13 48.0 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO24213.1 - 4.1e-10 38.4 4.6 0.018 13.2 0.0 4.3 1 1 3 4 4 4 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO24213.1 - 1.4e-08 34.5 0.4 9e-05 22.0 0.0 3.0 1 1 1 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO24213.1 - 2.3e-05 22.9 4.5 0.019 13.2 0.5 2.9 1 1 1 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO24213.1 - 0.00022 20.1 13.7 0.031 13.0 0.5 5.0 1 1 4 6 6 6 2 Nup133 N terminal like BBS2_Mid PF14783.1 ETO24213.1 - 0.0011 18.7 1.5 13 5.6 0.0 4.7 2 1 3 5 5 5 1 Ciliary BBSome complex subunit 2, middle region DUF3601 PF12208.3 ETO24213.1 - 0.0059 16.5 0.1 0.54 10.2 0.0 3.9 3 2 2 5 5 5 1 Domain of unknown function (DUF3601) DUF1258 PF06869.7 ETO24213.1 - 0.0062 15.6 2.2 2.2 7.2 0.1 3.5 2 2 1 3 3 3 2 Protein of unknown function (DUF1258) DUF4221 PF13970.1 ETO24213.1 - 0.0074 15.6 0.2 4.7 6.4 0.0 3.0 1 1 3 4 4 4 2 Domain of unknown function (DUF4221) PD40 PF07676.7 ETO24213.1 - 0.13 11.9 16.0 3.2 7.5 0.3 5.9 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Pkinase PF00069.20 ETO24215.1 - 5.2e-23 81.5 0.0 1.5e-22 79.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain DUF1981 PF09324.5 ETO24216.1 - 3.6e-11 42.4 1.7 2.4e-09 36.5 0.1 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF1981) Spt20 PF12090.3 ETO24217.1 - 1.2e-06 28.0 3.2 1.4e-06 27.8 2.2 1.1 1 0 0 1 1 1 1 Spt20 family Ipi1_N PF12333.3 ETO24217.1 - 0.00019 21.3 5.6 0.021 14.7 0.0 2.2 2 0 0 2 2 2 2 Rix1 complex component involved in 60S ribosome maturation Mem_trans PF03547.13 ETO24217.1 - 0.0011 17.3 0.3 0.0011 17.3 0.2 1.1 1 0 0 1 1 1 1 Membrane transport protein OmpH PF03938.9 ETO24217.1 - 0.0019 18.1 10.1 0.0024 17.8 7.0 1.2 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) RED_N PF07808.8 ETO24217.1 - 0.0047 16.1 5.6 0.0054 15.9 3.9 1.1 1 0 0 1 1 1 1 RED-like protein N-terminal region Cnd1 PF12717.2 ETO24217.1 - 0.0072 16.1 0.4 0.043 13.6 0.0 1.9 1 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 PEX11 PF05648.9 ETO24217.1 - 0.0078 15.5 1.6 0.028 13.6 0.6 1.9 2 0 0 2 2 2 1 Peroxisomal biogenesis factor 11 (PEX11) RAB3GAP2_N PF14655.1 ETO24217.1 - 0.0099 14.9 1.7 0.012 14.6 1.2 1.1 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus FemAB PF02388.11 ETO24217.1 - 0.013 14.2 3.8 0.017 13.8 2.6 1.1 1 0 0 1 1 1 0 FemAB family DUF3371 PF11851.3 ETO24217.1 - 0.014 16.0 5.0 0.019 15.6 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) VIT1 PF01988.14 ETO24217.1 - 0.016 14.7 0.4 0.016 14.7 0.3 1.4 2 0 0 2 2 2 0 VIT family Afi1 PF07792.7 ETO24217.1 - 0.016 15.2 3.3 0.016 15.2 2.3 1.5 2 0 0 2 2 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Tmemb_161AB PF10268.4 ETO24217.1 - 0.021 13.3 1.9 0.036 12.6 1.3 1.3 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB Med15 PF09606.5 ETO24217.1 - 0.025 12.8 13.5 0.031 12.5 9.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal AIF_C PF14721.1 ETO24217.1 - 0.034 14.3 2.2 0.067 13.4 1.5 1.6 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Glyco_transf_6 PF03414.8 ETO24217.1 - 0.044 12.2 3.0 0.061 11.7 2.1 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 6 HEAT_2 PF13646.1 ETO24217.1 - 0.093 13.0 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 HEAT repeats HEAT PF02985.17 ETO24217.1 - 0.11 12.6 0.0 0.57 10.3 0.0 2.1 2 0 0 2 2 2 0 HEAT repeat DUF1764 PF08576.5 ETO24217.1 - 0.25 12.1 7.4 0.36 11.6 5.1 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF4557 PF15101.1 ETO24217.1 - 0.26 11.0 8.3 0.35 10.6 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) FCP1_C PF09309.5 ETO24217.1 - 0.32 10.2 7.5 0.43 9.8 5.2 1.1 1 0 0 1 1 1 0 FCP1, C-terminal Cytadhesin_P30 PF07271.6 ETO24217.1 - 0.52 9.5 7.2 0.66 9.2 5.0 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 BAF1_ABF1 PF04684.8 ETO24217.1 - 0.57 8.9 11.8 0.73 8.6 8.2 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Pex16 PF08610.5 ETO24217.1 - 0.62 9.0 7.9 0.069 12.1 2.8 1.4 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) DUF2215 PF10225.4 ETO24217.1 - 0.9 8.9 4.1 0.65 9.4 1.6 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) RbsD_FucU PF05025.8 ETO24217.1 - 0.98 9.7 5.1 4.2 7.6 1.7 2.1 2 0 0 2 2 2 0 RbsD / FucU transport protein family DUF4175 PF13779.1 ETO24217.1 - 1.8 6.1 16.9 2.2 5.9 11.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Med3 PF11593.3 ETO24217.1 - 8.7 5.4 16.2 13 4.9 11.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Gag_spuma PF03276.9 ETO24217.1 - 9.8 4.3 13.1 13 3.9 9.1 1.1 1 0 0 1 1 1 0 Spumavirus gag protein FlaC_arch PF05377.6 ETO24218.1 - 0.26 11.2 1.6 0.32 10.9 0.2 1.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) ApoB100_C PF12491.3 ETO24219.1 - 0.058 13.0 0.1 0.16 11.6 0.1 1.7 1 0 0 1 1 1 0 Apolipoprotein B100 C terminal YABBY PF04690.8 ETO24220.1 - 0.44 10.7 3.1 0.61 10.3 2.1 1.2 1 0 0 1 1 1 0 YABBY protein DUF4179 PF13786.1 ETO24220.1 - 2.5 8.3 6.0 1.1 9.4 2.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4179) PA28_beta PF02252.13 ETO24223.1 - 1.7e-31 108.7 0.6 1.7e-31 108.7 0.4 1.9 2 0 0 2 2 2 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.13 ETO24223.1 - 0.072 13.2 0.1 0.24 11.6 0.1 2.0 1 1 0 1 1 1 0 Proteasome activator pa28 alpha subunit Ring_hydroxyl_A PF00848.14 ETO24224.1 - 0.003 17.2 1.0 0.0043 16.7 0.7 1.3 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) DUF2156 PF09924.4 ETO24225.1 - 9.1 4.9 6.9 0.67 8.7 1.1 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2156) Kelch_6 PF13964.1 ETO24226.1 - 8.4e-10 38.4 2.1 0.00014 21.8 0.0 4.9 5 1 1 6 6 6 2 Kelch motif Kelch_1 PF01344.20 ETO24226.1 - 1.4e-08 34.1 7.4 6.5e-06 25.6 0.0 4.1 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO24226.1 - 1.6e-05 24.4 2.9 0.14 11.9 0.0 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 ETO24226.1 - 1.9e-05 24.4 0.8 0.0011 18.8 0.0 3.2 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 ETO24226.1 - 0.0053 16.8 0.0 0.12 12.5 0.0 2.9 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO24226.1 - 0.011 15.5 2.9 2.5 7.9 0.0 4.3 4 1 0 4 4 4 0 Galactose oxidase, central domain Nbs1_C PF08599.5 ETO24226.1 - 0.029 14.2 2.3 0.053 13.4 0.9 2.0 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 WD40 PF00400.27 ETO24227.1 - 1e-46 155.1 17.4 5.7e-12 45.0 0.2 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO24227.1 - 1.6e-05 23.3 8.5 0.18 9.9 0.2 4.7 2 2 4 6 6 6 3 Nucleoporin Nup120/160 Nbas_N PF15492.1 ETO24227.1 - 0.00011 21.4 0.8 0.22 10.6 0.1 3.1 1 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 ETO24227.1 - 0.00099 17.9 15.0 0.27 9.9 2.4 4.8 1 1 2 3 3 3 3 Nup133 N terminal like PQQ_2 PF13360.1 ETO24227.1 - 0.015 14.7 0.9 0.13 11.7 0.6 2.4 1 1 0 1 1 1 0 PQQ-like domain Coatomer_WDAD PF04053.9 ETO24227.1 - 0.016 14.0 2.9 0.17 10.6 0.7 2.4 1 1 1 2 2 2 0 Coatomer WD associated region IMPDH PF00478.20 ETO24228.1 - 6.8e-128 426.4 2.7 1.9e-51 175.0 3.8 3.0 2 1 1 3 3 3 3 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 ETO24228.1 - 2.3e-12 46.4 0.0 6.8e-07 28.9 0.0 2.5 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 ETO24228.1 - 8.2e-07 28.4 1.0 0.016 14.3 0.3 3.0 3 0 0 3 3 3 2 Nitronate monooxygenase FMN_dh PF01070.13 ETO24228.1 - 3.3e-05 22.8 0.8 6.1e-05 22.0 0.5 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 ETO24228.1 - 0.0037 16.5 0.5 2.1 7.5 0.0 3.2 2 1 1 3 3 3 1 Histidine biosynthesis protein DUF647 PF04884.9 ETO24229.1 - 2.6e-47 161.1 3.8 6.6e-34 117.2 0.1 2.3 2 0 0 2 2 2 2 Vitamin B6 photo-protection and homoeostasis Beta-Casp PF10996.3 ETO24230.1 - 1.2e-05 25.2 0.0 2.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_2 PF12706.2 ETO24230.1 - 2.9e-05 23.7 0.0 4.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 ETO24230.1 - 9.3e-05 22.1 0.0 0.00016 21.4 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily SHMT PF00464.14 ETO24232.1 - 1.1e-184 613.4 0.0 1.3e-184 613.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 ETO24232.1 - 0.077 12.1 0.0 0.14 11.2 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase DUF3605 PF12239.3 ETO24233.1 - 1.6e-12 47.5 1.3 3.4e-12 46.4 0.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) DEAD PF00270.24 ETO24234.1 - 9.5e-14 51.2 0.2 1.7e-12 47.1 0.0 2.9 3 1 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.10 ETO24234.1 - 0.0001 22.2 0.0 0.004 17.0 0.0 3.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 ETO24234.1 - 0.00067 19.8 0.1 0.01 15.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Helicase_C PF00271.26 ETO24234.1 - 0.005 16.6 0.0 0.025 14.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA PF00004.24 ETO24234.1 - 0.01 16.0 0.2 0.035 14.3 0.2 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DNA_pol_A PF00476.15 ETO24236.1 - 8.2e-05 21.3 0.0 0.38 9.3 0.0 3.4 2 1 1 3 3 3 3 DNA polymerase family A DNA_pol_A PF00476.15 ETO24237.1 - 3.8e-41 141.0 0.6 6.5e-41 140.2 0.4 1.3 1 1 0 1 1 1 1 DNA polymerase family A Erv26 PF04148.8 ETO24237.1 - 0.03 13.7 0.1 0.051 12.9 0.1 1.3 1 0 0 1 1 1 0 Transmembrane adaptor Erv26 DUF1743 PF08489.6 ETO24237.1 - 0.09 12.5 0.1 0.37 10.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1743) Citrate_synt PF00285.16 ETO24238.1 - 4.4e-28 98.0 0.0 6.4e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Citrate synthase LMBR1 PF04791.11 ETO24239.1 - 0.0025 16.4 0.8 0.0036 15.9 0.5 1.3 1 1 0 1 1 1 1 LMBR1-like membrane protein ABC2_membrane_3 PF12698.2 ETO24239.1 - 0.012 14.6 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein zf-LITAF-like PF10601.4 ETO24239.1 - 0.043 13.6 4.3 0.06 13.2 3.0 1.3 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain Dsh_C PF12316.3 ETO24239.1 - 0.1 12.6 1.8 0.13 12.3 1.3 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Ribosomal_S8e PF01201.17 ETO24239.1 - 0.14 12.2 4.6 0.19 11.9 3.2 1.4 1 0 0 1 1 1 0 Ribosomal protein S8e Borrelia_P83 PF05262.6 ETO24239.1 - 0.15 10.3 16.1 0.17 10.1 11.2 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4407 PF14362.1 ETO24239.1 - 0.4 9.6 8.5 0.68 8.8 5.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Striatin PF08232.7 ETO24239.1 - 0.64 10.3 14.1 0.95 9.7 9.8 1.2 1 0 0 1 1 1 0 Striatin family ALMT PF11744.3 ETO24239.1 - 0.83 8.2 3.3 1 7.9 2.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2514 PF10721.4 ETO24239.1 - 0.87 9.2 4.9 1.2 8.8 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) DUF4614 PF15391.1 ETO24239.1 - 1.1 8.9 6.0 1.5 8.5 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Vfa1 PF08432.5 ETO24239.1 - 2.2 8.3 19.1 3 7.8 13.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 eIF-3c_N PF05470.7 ETO24239.1 - 3.2 5.7 16.6 4.2 5.3 11.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Rota_VP2 PF05087.7 ETO24239.1 - 3.4 5.4 13.4 4.2 5.1 9.3 1.0 1 0 0 1 1 1 0 Rotavirus VP2 protein RR_TM4-6 PF06459.7 ETO24239.1 - 4.4 7.1 16.5 6.2 6.6 11.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.9 ETO24239.1 - 5.4 4.9 8.5 5.4 4.9 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Rtf2 PF04641.7 ETO24239.1 - 6.9 5.7 21.6 9.4 5.3 14.9 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger U5_2-snRNA_bdg PF10597.4 ETO24240.1 - 0.63 9.6 3.9 0.55 9.8 1.5 1.7 1 1 1 2 2 2 0 U5-snRNA binding site 2 of PrP8 Kelch_2 PF07646.10 ETO24241.1 - 0.057 13.2 1.5 17 5.3 0.1 3.5 3 0 0 3 3 3 0 Kelch motif Kelch_1 PF01344.20 ETO24241.1 - 0.081 12.4 5.7 2.3 7.8 0.0 4.6 4 0 0 4 4 4 0 Kelch motif Kelch_6 PF13964.1 ETO24241.1 - 0.43 10.8 3.7 14 6.0 0.1 3.6 4 0 0 4 4 4 0 Kelch motif Mit_KHE1 PF10173.4 ETO24241.1 - 5.1 6.8 13.9 4.3 7.1 7.6 2.0 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related zf-H2C2_2 PF13465.1 ETO24242.1 - 0.023 14.9 0.6 0.023 14.9 0.4 2.2 1 1 0 1 1 1 0 Zinc-finger double domain MAM1 PF10434.4 ETO24242.1 - 0.46 9.6 7.7 0.72 9.0 5.3 1.5 1 1 0 1 1 1 0 Monopolin complex protein MAM1 zf-C2H2 PF00096.21 ETO24242.1 - 0.76 10.2 8.3 0.47 10.9 0.5 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type FAD_binding_3 PF01494.14 ETO24243.1 - 0.00037 19.6 0.0 7.6 5.4 0.0 3.9 4 0 0 4 4 4 3 FAD binding domain CobT PF06213.7 ETO24243.1 - 0.13 11.4 1.1 0.21 10.6 0.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RQC PF09382.5 ETO24243.1 - 0.15 11.8 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 RQC domain Apis_Csd PF11671.3 ETO24243.1 - 0.34 10.6 11.2 0.73 9.6 7.8 1.5 1 0 0 1 1 1 0 Complementary sex determiner protein DUF2457 PF10446.4 ETO24243.1 - 2.8 6.5 4.6 4.4 5.9 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Laminin_G_2 PF02210.19 ETO24244.1 - 0.0024 17.8 0.0 0.0055 16.7 0.0 1.6 1 0 0 1 1 1 1 Laminin G domain SPRY PF00622.23 ETO24244.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 SPRY domain DIM1 PF02966.11 ETO24245.1 - 4.2e-46 155.7 1.1 4.7e-46 155.5 0.7 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 CAMP_factor PF07373.6 ETO24246.1 - 0.05 13.1 0.0 0.066 12.7 0.0 1.1 1 0 0 1 1 1 0 CAMP factor (Cfa) DUF2746 PF10874.3 ETO24247.1 - 0.0075 16.4 1.0 0.017 15.2 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2746) DUF2721 PF11026.3 ETO24247.1 - 0.018 14.6 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Arfaptin PF06456.8 ETO24247.1 - 0.037 13.3 0.1 0.059 12.7 0.1 1.3 1 0 0 1 1 1 0 Arfaptin-like domain FliG_M PF14841.1 ETO24247.1 - 0.059 13.3 0.5 3.4 7.7 0.4 2.7 2 1 0 2 2 2 0 FliG middle domain EURL PF06937.6 ETO24247.1 - 0.06 12.7 0.6 0.081 12.3 0.4 1.2 1 0 0 1 1 1 0 EURL protein DUF3584 PF12128.3 ETO24248.1 - 0.14 9.4 34.6 0.22 8.8 24.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Mnd1 PF03962.10 ETO24248.1 - 0.25 11.0 37.6 1.1 8.9 14.2 2.2 1 1 1 2 2 2 0 Mnd1 family IncA PF04156.9 ETO24248.1 - 0.33 10.5 48.8 5.2 6.6 9.9 2.1 1 1 1 2 2 2 0 IncA protein Spc7 PF08317.6 ETO24248.1 - 0.54 8.8 36.3 0.44 9.1 16.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Filament PF00038.16 ETO24248.1 - 1.5 8.1 38.8 0.84 9.0 18.1 2.1 1 1 1 2 2 2 0 Intermediate filament protein Tropomyosin_1 PF12718.2 ETO24248.1 - 2.6 7.8 42.4 4.1 7.2 17.4 2.1 1 1 1 2 2 2 0 Tropomyosin like Vac_Fusion PF02346.11 ETO24248.1 - 2.8 7.4 8.8 1.6 8.2 0.1 3.6 2 1 0 3 3 3 0 Chordopoxvirus fusion protein ArdA PF07275.6 ETO24248.1 - 3.5 7.8 13.3 0.9 9.7 5.9 2.2 1 1 1 2 2 2 0 Antirestriction protein (ArdA) UPF0231 PF06062.6 ETO24248.1 - 3.6 7.4 15.1 1.7 8.5 5.3 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0231) DUF3695 PF12494.3 ETO24248.1 - 5.9 6.6 13.7 1.2 8.9 0.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3695) Seryl_tRNA_N PF02403.17 ETO24248.1 - 6.2 6.8 30.7 0.49 10.4 9.8 3.0 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 PF07926.7 ETO24248.1 - 9.4 5.9 48.6 5.4 6.7 6.9 3.3 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein fn3 PF00041.16 ETO24249.1 - 4.1e-14 52.4 1.0 1.7e-09 37.7 0.2 2.6 3 0 0 3 3 3 2 Fibronectin type III domain Erf4 PF10256.4 ETO24249.1 - 0.045 13.6 0.5 0.13 12.1 0.1 1.9 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family TPR_14 PF13428.1 ETO24250.1 - 0.0071 16.8 1.0 0.12 13.0 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO24250.1 - 0.093 12.3 6.1 3.1 7.4 0.0 2.9 3 0 0 3 3 3 0 TPR repeat TPR_2 PF07719.12 ETO24250.1 - 0.21 11.5 1.5 6 7.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETO24250.1 - 0.24 11.7 2.1 2.5 8.4 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Plasmid_killer PF05015.8 ETO24251.1 - 0.026 14.6 1.1 0.061 13.4 0.3 1.8 2 0 0 2 2 2 0 Plasmid maintenance system killer protein DUF1387 PF07139.6 ETO24251.1 - 2.2 7.8 15.2 1.9 8.0 4.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1387) SAM_1 PF00536.25 ETO24252.1 - 3.4e-12 46.3 2.6 1.1e-05 25.4 0.2 2.7 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 ETO24252.1 - 1e-06 28.3 0.7 0.055 13.2 0.0 3.7 3 0 0 3 3 3 2 Sterile alpha motif (SAM)/Pointed domain zf-MYND PF01753.13 ETO24252.1 - 2.2e-05 24.2 15.1 5.6e-05 22.9 10.5 1.7 1 0 0 1 1 1 1 MYND finger DUF1421 PF07223.6 ETO24252.1 - 0.038 13.7 36.4 0.071 12.8 25.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) DUF1639 PF07797.9 ETO24252.1 - 2.6 7.4 8.6 1.9 7.9 1.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1639) G-alpha PF00503.15 ETO24254.1 - 5e-08 32.0 1.0 6.4e-08 31.6 0.7 1.1 1 0 0 1 1 1 1 G-protein alpha subunit NB-ARC PF00931.17 ETO24254.1 - 0.045 12.6 0.5 0.066 12.0 0.4 1.4 1 1 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.1 ETO24254.1 - 0.077 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 ETO24254.1 - 0.092 13.0 0.1 0.2 11.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain ubiquitin PF00240.18 ETO24256.1 - 6.3e-22 76.7 2.0 1.8e-19 68.8 0.6 3.2 3 0 0 3 3 3 2 Ubiquitin family Rad60-SLD PF11976.3 ETO24256.1 - 1.5e-10 40.5 2.9 5.7e-09 35.5 0.5 2.9 3 1 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like GABP-alpha PF11620.3 ETO24256.1 - 0.0076 16.2 0.6 0.88 9.5 0.1 2.2 1 1 1 2 2 2 2 GA-binding protein alpha chain Nup35_RRM_2 PF14605.1 ETO24258.1 - 0.03 14.0 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF1830 PF08865.6 ETO24258.1 - 0.083 12.5 0.0 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1830) ASL_C PF08328.6 ETO24258.1 - 0.1 12.4 2.0 0.14 11.9 1.4 1.2 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal Sec62 PF03839.11 ETO24258.1 - 5.5 6.3 7.5 7.4 5.9 5.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Vps39_1 PF10366.4 ETO24258.1 - 5.9 6.9 6.9 9.1 6.3 2.7 2.3 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 DUF1352 PF07086.7 ETO24260.1 - 5.9e-05 22.7 2.4 0.00013 21.6 0.1 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1352) CD36 PF01130.16 ETO24261.1 - 6.6e-44 149.9 9.5 1.4e-24 86.2 3.5 2.3 2 0 0 2 2 2 2 CD36 family TMCO5 PF14992.1 ETO24261.1 - 3.2 6.8 5.7 4.8 6.2 4.0 1.2 1 0 0 1 1 1 0 TMCO5 family RGS PF00615.14 ETO24262.1 - 3.4e-05 23.9 0.3 0.00058 19.9 0.2 2.5 1 1 0 1 1 1 1 Regulator of G protein signaling domain WD40 PF00400.27 ETO24263.1 - 1.7e-62 205.2 29.3 1.7e-10 40.3 0.5 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO24263.1 - 1.8e-09 36.3 2.5 0.0066 14.6 0.0 5.5 1 1 4 6 6 6 4 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO24263.1 - 3e-05 24.2 1.5 0.00015 22.0 1.0 2.3 1 0 0 1 1 1 1 TRAF-type zinc finger Hom_end_hint PF05203.11 ETO24263.1 - 0.13 11.9 10.4 0.26 10.9 7.2 1.4 1 0 0 1 1 1 0 Hom_end-associated Hint Phage_GPO PF05929.6 ETO24263.1 - 2.7 7.1 11.4 4.6 6.4 7.9 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Rootletin PF15035.1 ETO24263.1 - 2.8 7.8 25.0 7.2 6.5 17.3 1.6 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF1777 PF08648.7 ETO24265.1 - 0.00041 20.1 35.5 0.00041 20.1 24.6 4.9 5 0 0 5 5 5 2 Protein of unknown function (DUF1777) F5_F8_type_C PF00754.20 ETO24266.1 - 0.088 12.6 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 F5/8 type C domain DUF4598 PF15370.1 ETO24266.1 - 0.1 12.9 4.8 0.13 12.5 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4598) DUF912 PF06024.7 ETO24267.1 - 0.019 15.0 2.0 0.019 15.0 1.4 2.4 1 1 2 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Plasmodium_Vir PF05795.6 ETO24267.1 - 0.034 13.3 7.9 0.054 12.7 5.5 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TrbL PF04610.9 ETO24267.1 - 0.049 13.3 0.6 0.1 12.2 0.4 1.5 1 1 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Peptidase_M56 PF05569.6 ETO24267.1 - 0.067 12.1 1.3 0.088 11.7 0.6 1.4 1 1 0 1 1 1 0 BlaR1 peptidase M56 Claudin_2 PF13903.1 ETO24267.1 - 2.6 7.7 9.6 0.055 13.1 1.8 1.9 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF2547 PF10818.3 ETO24267.1 - 5.2 7.7 11.6 9.6 6.9 2.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2547) IF3_N PF05198.11 ETO24268.1 - 0.06 13.2 2.2 0.086 12.7 1.2 1.5 1 1 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain TMPIT PF07851.8 ETO24269.1 - 2.7e-39 135.1 18.6 3.5e-39 134.7 12.9 1.0 1 0 0 1 1 1 1 TMPIT-like protein DUF3584 PF12128.3 ETO24269.1 - 0.0015 15.9 2.6 0.0019 15.6 1.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Spc7 PF08317.6 ETO24269.1 - 0.0027 16.4 11.8 0.0046 15.6 8.2 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Phage_GP20 PF06810.6 ETO24269.1 - 0.0043 16.4 7.3 0.0046 16.4 4.3 1.5 1 1 0 1 1 1 1 Phage minor structural protein GP20 COG2 PF06148.6 ETO24269.1 - 0.0066 16.3 4.4 0.017 14.9 3.0 1.8 1 1 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Laminin_II PF06009.7 ETO24269.1 - 0.0072 16.0 5.7 0.012 15.3 4.0 1.3 1 0 0 1 1 1 1 Laminin Domain II FliD_C PF07195.7 ETO24269.1 - 0.015 14.5 4.5 0.015 14.5 3.1 1.7 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus CENP-Q PF13094.1 ETO24269.1 - 0.024 14.6 8.7 0.041 13.9 6.0 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Myb_DNA-bind_5 PF13873.1 ETO24269.1 - 0.045 13.6 4.4 0.094 12.6 1.4 2.4 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain RGCC PF15151.1 ETO24269.1 - 0.11 12.9 2.0 0.98 9.8 0.2 2.1 1 1 1 2 2 2 0 Response gene to complement 32 protein family YjcZ PF13990.1 ETO24269.1 - 0.19 10.8 5.0 1.2 8.1 1.3 2.4 2 1 0 2 2 2 0 YjcZ-like protein Prefoldin PF02996.12 ETO24269.1 - 0.2 11.3 10.0 0.16 11.6 1.2 2.8 1 1 1 2 2 2 0 Prefoldin subunit DUF2262 PF10020.4 ETO24269.1 - 0.21 11.7 6.0 0.43 10.7 4.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2262) Nup54 PF13874.1 ETO24269.1 - 0.26 10.9 7.8 0.55 9.9 5.4 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 ACCA PF03255.9 ETO24269.1 - 0.27 10.7 6.4 0.4 10.2 3.4 1.9 1 1 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF1664 PF07889.7 ETO24269.1 - 0.39 10.5 9.8 0.11 12.3 4.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.2 ETO24269.1 - 0.44 10.3 12.0 0.87 9.4 8.3 1.4 1 0 0 1 1 1 0 Tropomyosin like Uds1 PF15456.1 ETO24269.1 - 0.63 10.0 6.8 1.1 9.2 4.7 1.3 1 0 0 1 1 1 0 Up-regulated During Septation Prominin PF05478.6 ETO24269.1 - 0.67 7.4 7.7 0.98 6.8 5.4 1.2 1 0 0 1 1 1 0 Prominin Sec20 PF03908.8 ETO24269.1 - 0.83 9.3 5.7 0.82 9.4 2.3 2.4 2 1 0 2 2 1 0 Sec20 DUF342 PF03961.8 ETO24269.1 - 1 7.7 8.6 1.4 7.2 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Seryl_tRNA_N PF02403.17 ETO24269.1 - 1.3 9.0 6.8 3 7.8 4.7 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Rho_Binding PF08912.6 ETO24269.1 - 1.8 8.8 15.6 0.35 11.2 3.5 2.7 1 1 1 2 2 2 0 Rho Binding Fib_alpha PF08702.5 ETO24269.1 - 2 8.5 11.7 15 5.6 8.1 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF745 PF05335.8 ETO24269.1 - 2.4 7.6 5.5 1.6 8.1 2.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF745) Syntaxin PF00804.20 ETO24269.1 - 2.6 8.2 10.3 4.2 7.5 5.6 2.1 1 1 1 2 2 2 0 Syntaxin IncA PF04156.9 ETO24269.1 - 2.8 7.5 10.4 5.2 6.6 7.2 1.4 1 0 0 1 1 1 0 IncA protein NPV_P10 PF05531.7 ETO24269.1 - 2.8 8.2 4.9 14 6.0 3.4 2.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.6 ETO24269.1 - 3 7.7 11.3 0.31 10.9 3.1 2.7 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) Streptin-Immun PF11083.3 ETO24269.1 - 3 7.8 10.3 0.62 10.0 2.5 2.3 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein CENP-H PF05837.7 ETO24269.1 - 6.2 7.0 11.0 4.9 7.3 5.2 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) FlxA PF14282.1 ETO24269.1 - 7.3 6.5 12.3 25 4.8 8.3 2.0 1 1 1 2 2 2 0 FlxA-like protein Mucin2_WxxW PF13330.1 ETO24271.1 - 0.28 11.6 1.8 6.5 7.2 0.1 2.7 3 0 0 3 3 3 0 Mucin-2 protein WxxW repeating region ABC_tran PF00005.22 ETO24272.1 - 3.1e-06 27.5 4.3 6.4e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 ABC transporter SR-25 PF10500.4 ETO24272.1 - 0.021 14.3 11.0 0.032 13.6 7.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ABC_tran PF00005.22 ETO24273.1 - 5.9e-16 59.0 0.0 5.9e-16 59.0 0.0 3.0 2 1 1 3 3 2 1 ABC transporter SMC_N PF02463.14 ETO24273.1 - 4.6e-06 26.0 0.8 1e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 ETO24273.1 - 0.0023 18.3 0.3 0.0023 18.3 0.2 3.8 2 2 1 3 3 1 1 AAA domain MMR_HSR1 PF01926.18 ETO24273.1 - 0.0025 17.7 0.5 0.012 15.5 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 ETO24273.1 - 0.0032 17.3 0.1 0.0032 17.3 0.1 3.6 3 2 0 3 3 2 1 Dynamin family AAA_29 PF13555.1 ETO24273.1 - 0.0041 16.6 0.2 0.0094 15.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Miro PF08477.8 ETO24273.1 - 0.0044 17.5 2.1 0.0079 16.6 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 ETO24273.1 - 0.014 14.5 0.1 0.034 13.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 ETO24273.1 - 0.062 14.1 1.8 0.17 12.7 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 ETO24273.1 - 0.23 11.3 0.0 0.23 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 ETO24273.1 - 1.2 9.4 0.0 1.2 9.4 0.0 3.8 3 1 0 3 3 2 0 AAA domain Daxx PF03344.10 ETO24273.1 - 9.4 4.5 36.7 0.007 14.9 9.9 2.9 3 0 0 3 3 3 0 Daxx Family Lipase_3 PF01764.20 ETO24274.1 - 1.3e-25 89.6 0.1 2.6e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 ETO24274.1 - 0.065 12.9 0.0 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Vps26 PF03643.10 ETO24275.1 - 9.1e-18 64.0 0.2 1e-17 63.8 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 ETO24275.1 - 1.4e-08 34.6 0.3 3.8e-08 33.2 0.2 1.6 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Nucleoplasmin PF03066.10 ETO24276.1 - 0.0019 17.7 0.5 0.12 11.8 0.0 2.4 2 0 0 2 2 2 2 Nucleoplasmin MRP-S33 PF08293.6 ETO24277.1 - 0.027 14.4 0.9 3.6 7.6 0.1 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit S27 DUF563 PF04577.9 ETO24278.1 - 4.2e-15 56.2 0.8 1e-14 54.9 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF563) DUF4653 PF15546.1 ETO24279.1 - 0.00094 18.5 0.8 0.0014 17.9 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4653) Caps_synth PF05704.7 ETO24279.1 - 0.08 12.0 3.3 1.5 7.9 1.1 2.2 1 1 1 2 2 2 0 Capsular polysaccharide synthesis protein DUF2051 PF09738.4 ETO24280.1 - 0.006 15.9 3.0 0.008 15.5 2.1 1.1 1 0 0 1 1 1 1 Double stranded RNA binding protein (DUF2051) Esterase PF00756.15 ETO24280.1 - 0.087 12.2 2.2 1.6 8.1 0.1 2.0 2 0 0 2 2 2 0 Putative esterase AAA_4 PF04326.9 ETO24281.1 - 9.9e-08 32.1 0.8 3.1e-07 30.5 0.1 2.2 2 0 0 2 2 2 1 Divergent AAA domain Neur_chan_memb PF02932.11 ETO24281.1 - 0.26 11.1 7.8 0.019 14.8 1.7 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF4448 PF14610.1 ETO24281.1 - 3.6 7.0 7.5 14 5.1 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) DUF4409 PF14365.1 ETO24283.1 - 0.028 14.5 0.8 0.041 14.0 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4409) DUF719 PF05334.8 ETO24283.1 - 0.1 12.6 0.5 0.12 12.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF719) DUF912 PF06024.7 ETO24283.1 - 0.44 10.6 4.4 0.66 10.0 3.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3682 PF12446.3 ETO24284.1 - 0.31 11.3 7.3 0.75 10.0 5.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) UPF0051 PF01458.12 ETO24286.1 - 0.14 11.6 0.1 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein family (UPF0051) EF-hand_6 PF13405.1 ETO24287.1 - 0.0031 17.2 0.1 0.018 14.9 0.0 2.4 1 1 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.1 ETO24287.1 - 0.004 16.7 0.3 0.98 9.0 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair DUF1018 PF06252.7 ETO24287.1 - 0.07 13.6 3.2 2.9 8.4 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1018) OST-HTH PF12872.2 ETO24287.1 - 0.084 12.7 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 OST-HTH/LOTUS domain TRAP_alpha PF03896.11 ETO24288.1 - 0.0025 16.8 7.2 0.003 16.6 5.0 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Daxx PF03344.10 ETO24288.1 - 0.0032 16.0 11.0 0.0035 15.9 7.6 1.2 1 0 0 1 1 1 1 Daxx Family RR_TM4-6 PF06459.7 ETO24288.1 - 0.013 15.3 15.6 0.019 14.8 10.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MIP-T3 PF10243.4 ETO24288.1 - 0.042 12.3 21.7 0.047 12.1 15.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RRN3 PF05327.6 ETO24288.1 - 0.15 10.1 8.3 0.16 10.0 5.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ycf1 PF05758.7 ETO24288.1 - 0.26 8.9 16.0 0.31 8.7 11.1 1.2 1 0 0 1 1 1 0 Ycf1 CDC45 PF02724.9 ETO24288.1 - 0.36 8.8 11.0 0.42 8.5 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Atrophin-1 PF03154.10 ETO24288.1 - 0.65 8.0 26.1 0.94 7.5 18.1 1.2 1 0 0 1 1 1 0 Atrophin-1 family DUF3306 PF11748.3 ETO24288.1 - 1.2 9.8 11.5 2.2 8.9 8.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Trypan_PARP PF05887.6 ETO24288.1 - 2 8.2 23.6 2.8 7.7 16.4 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Vfa1 PF08432.5 ETO24288.1 - 3.8 7.4 27.4 1.5 8.8 16.7 1.7 1 1 1 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Adaptin_binding PF10199.4 ETO24288.1 - 4.4 7.5 17.7 6.3 7.0 12.3 1.3 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DUF3530 PF12048.3 ETO24288.1 - 4.5 6.1 9.5 6 5.7 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DUF740 PF05340.7 ETO24288.1 - 5.6 5.1 10.4 6.1 5.0 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF740) DUF3332 PF11810.3 ETO24288.1 - 5.8 6.5 7.4 1.3 8.6 1.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3332) Presenilin PF01080.12 ETO24289.1 - 1.1 7.9 8.3 2 7.1 5.7 1.4 1 0 0 1 1 1 0 Presenilin FLO_LFY PF01698.11 ETO24289.1 - 1.6 7.5 10.4 2.2 7.0 7.2 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Hid1 PF12722.2 ETO24289.1 - 5.6 4.5 13.0 7.6 4.0 9.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Prog_receptor PF02161.10 ETO24289.1 - 9 4.9 8.4 12 4.5 5.8 1.1 1 0 0 1 1 1 0 Progesterone receptor SBDS_C PF09377.5 ETO24290.1 - 8.3e-35 119.2 0.4 1.7e-34 118.1 0.3 1.5 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 ETO24290.1 - 1.3e-20 72.9 2.0 2.2e-20 72.2 0.9 1.8 1 1 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein zf-AD PF07776.10 ETO24290.1 - 0.062 13.3 0.3 0.17 11.8 0.2 1.8 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) bHLH-MYC_N PF14215.1 ETO24290.1 - 0.13 12.4 0.3 0.23 11.6 0.2 1.4 1 0 0 1 1 1 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal CesA PF11439.3 ETO24290.1 - 0.17 11.8 2.3 0.33 10.9 0.7 2.1 2 0 0 2 2 2 0 Type III secretion system filament chaperone CesA zf-C4pol PF14260.1 ETO24290.1 - 0.32 11.0 2.0 1.5 8.8 0.2 2.3 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta dsDNA_bind PF01984.15 ETO24291.1 - 8.1e-05 22.5 0.7 8.1e-05 22.5 0.5 2.2 1 1 1 2 2 2 1 Double-stranded DNA-binding domain DNA_pol_B PF00136.16 ETO24291.1 - 0.054 12.2 3.3 0.059 12.1 2.3 1.0 1 0 0 1 1 1 0 DNA polymerase family B DUF3223 PF11523.3 ETO24291.1 - 0.13 12.5 0.5 0.28 11.5 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3223) Adeno_E3_15_3 PF03307.9 ETO24291.1 - 0.25 11.0 6.7 0.7 9.6 4.5 1.9 1 1 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region Ribosomal_L9_C PF03948.9 ETO24291.1 - 1.2 9.2 6.4 0.098 12.7 0.5 1.9 2 0 0 2 2 2 0 Ribosomal protein L9, C-terminal domain Ribosomal_S13 PF00416.17 ETO24292.1 - 1.1e-14 54.7 0.0 2e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 ETO24292.1 - 0.028 12.9 0.0 0.038 12.5 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Sec5 PF15469.1 ETO24293.1 - 9.9e-33 113.3 11.6 1.6e-32 112.7 5.9 2.9 2 0 0 2 2 2 1 Exocyst complex component Sec5 MutS_III PF05192.13 ETO24293.1 - 0.0052 16.6 0.2 0.56 9.9 0.2 2.9 1 1 0 1 1 1 1 MutS domain III DUF4446 PF14584.1 ETO24293.1 - 0.076 12.8 0.1 0.076 12.8 0.0 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF4446) UPF0118 PF01594.11 ETO24293.1 - 2.1 7.2 5.4 0.4 9.6 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF20 Scs3p PF10261.4 ETO24294.1 - 0.1 11.5 0.1 0.1 11.5 0.1 2.4 3 0 0 3 3 3 0 Inositol phospholipid synthesis and fat-storage-inducing TM PPI_Ypi1 PF07491.6 ETO24294.1 - 2.4 7.8 5.9 3.4 7.3 0.0 3.4 4 0 0 4 4 4 0 Protein phosphatase inhibitor TIMP PF00965.12 ETO24295.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.4 1 1 0 1 1 1 0 Tissue inhibitor of metalloproteinase DUF2413 PF10310.4 ETO24296.1 - 0.1 11.4 20.0 0.11 11.2 13.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF648 PF04890.8 ETO24296.1 - 0.23 10.5 11.0 0.25 10.4 7.6 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF648) CDC45 PF02724.9 ETO24296.1 - 0.66 7.9 15.4 0.71 7.8 10.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1977 PF09320.6 ETO24296.1 - 2.3 8.4 12.8 13 6.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1977) DUF913 PF06025.7 ETO24296.1 - 4.2 6.0 6.8 5.3 5.6 4.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SprA-related PF12118.3 ETO24296.1 - 5.6 6.1 16.3 7.8 5.7 11.3 1.2 1 0 0 1 1 1 0 SprA-related family DUF2201_N PF13203.1 ETO24296.1 - 9.2 5.3 9.0 12 4.9 6.2 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain HMG_CoA_synt_N PF01154.12 ETO24297.1 - 1.3e-75 252.7 0.1 5.3e-51 172.6 0.1 2.3 2 0 0 2 2 2 2 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.5 ETO24297.1 - 6.9e-64 216.0 15.9 2.2e-32 112.7 1.6 3.3 2 1 0 3 3 3 3 Hydroxymethylglutaryl-coenzyme A synthase C terminal SAM_2 PF07647.12 ETO24298.1 - 1.4e-06 28.0 1.0 2.8e-05 23.8 0.1 2.5 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Rootletin PF15035.1 ETO24298.1 - 4.1e-05 23.6 11.7 4.1e-05 23.6 8.1 2.2 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion MAD PF05557.8 ETO24298.1 - 0.0034 15.5 7.5 0.0034 15.5 5.2 3.0 2 1 0 3 3 3 1 Mitotic checkpoint protein Tup_N PF08581.5 ETO24298.1 - 0.0035 17.4 2.0 0.0035 17.4 1.4 3.1 3 0 0 3 3 2 2 Tup N-terminal SAM_1 PF00536.25 ETO24298.1 - 0.0036 17.4 0.2 0.0086 16.2 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Snapin_Pallidin PF14712.1 ETO24298.1 - 0.0045 17.2 10.0 0.0045 17.2 6.9 2.8 3 1 0 3 3 2 1 Snapin/Pallidin Cep57_CLD_2 PF14197.1 ETO24298.1 - 0.0058 16.5 7.6 0.0058 16.5 5.3 4.0 4 0 0 4 4 4 1 Centrosome localisation domain of PPC89 DUF2046 PF09755.4 ETO24298.1 - 0.011 14.6 4.4 0.011 14.6 3.1 3.4 2 1 1 3 3 3 0 Uncharacterized conserved protein H4 (DUF2046) DUF4407 PF14362.1 ETO24298.1 - 0.05 12.5 17.3 0.009 14.9 5.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) EMP24_GP25L PF01105.19 ETO24298.1 - 0.13 11.9 6.5 1.4 8.6 1.9 2.5 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Tropomyosin_1 PF12718.2 ETO24298.1 - 0.13 12.0 32.3 0.023 14.5 14.6 3.0 2 1 0 2 2 2 0 Tropomyosin like Reo_sigmaC PF04582.7 ETO24298.1 - 0.14 11.3 6.7 0.025 13.7 0.5 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein CASP_C PF08172.7 ETO24298.1 - 0.25 10.3 12.6 0.096 11.6 2.1 2.5 2 0 0 2 2 2 0 CASP C terminal DUF382 PF04037.8 ETO24298.1 - 0.27 11.0 2.7 0.22 11.3 0.6 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF382) Atg14 PF10186.4 ETO24298.1 - 0.35 9.7 24.5 0.013 14.4 8.1 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Striatin PF08232.7 ETO24298.1 - 0.38 11.0 23.3 0.72 10.1 9.0 3.2 2 1 1 3 3 3 0 Striatin family DUF603 PF04645.7 ETO24298.1 - 0.39 10.6 11.4 3.6 7.4 2.1 2.6 2 2 0 2 2 2 0 Protein of unknown function, DUF603 Spc7 PF08317.6 ETO24298.1 - 0.46 9.0 26.9 0.2 10.2 9.1 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Syja_N PF02383.13 ETO24298.1 - 0.5 9.0 5.2 0.12 11.1 0.3 2.0 2 0 0 2 2 2 0 SacI homology domain RmuC PF02646.11 ETO24298.1 - 0.58 8.9 19.7 0.13 11.0 5.0 2.2 2 0 0 2 2 2 0 RmuC family V_ATPase_I PF01496.14 ETO24298.1 - 0.85 7.3 14.9 0.071 10.9 4.6 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family ABC_trans_N PF14510.1 ETO24298.1 - 0.95 9.5 5.8 0.41 10.7 1.1 2.4 1 1 0 2 2 2 0 ABC-transporter extracellular N-terminal DUF342 PF03961.8 ETO24298.1 - 0.98 7.7 21.6 0.89 7.8 2.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF342) DUF4164 PF13747.1 ETO24298.1 - 1.1 9.4 20.8 0.069 13.2 7.4 3.2 2 2 1 3 3 3 0 Domain of unknown function (DUF4164) Nup54 PF13874.1 ETO24298.1 - 1.2 8.8 20.9 0.07 12.7 7.0 2.6 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 ATG16 PF08614.6 ETO24298.1 - 1.2 8.8 27.8 0.7 9.6 9.5 2.5 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) TEX13 PF15186.1 ETO24298.1 - 1.4 8.5 12.3 3.7 7.1 3.4 2.7 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family DUF4559 PF15112.1 ETO24298.1 - 1.4 7.9 14.6 0.22 10.6 4.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) Pox_A_type_inc PF04508.7 ETO24298.1 - 1.7 8.6 13.3 2.3 8.2 0.1 5.1 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat Baculo_PEP_C PF04513.7 ETO24298.1 - 1.7 8.4 16.8 0.49 10.2 6.4 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spectrin PF00435.16 ETO24298.1 - 1.8 8.8 20.4 0.2 11.9 6.6 2.9 2 2 0 2 2 2 0 Spectrin repeat APG6 PF04111.7 ETO24298.1 - 1.9 7.4 28.0 0.16 11.0 10.1 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 Mnd1 PF03962.10 ETO24298.1 - 2 8.0 22.3 5 6.7 9.4 2.8 2 1 1 3 3 3 0 Mnd1 family DUF3584 PF12128.3 ETO24298.1 - 2 5.6 26.6 0.078 10.3 11.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Cep57_CLD PF14073.1 ETO24298.1 - 2.4 7.9 28.2 0.053 13.3 10.0 2.1 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 Filament PF00038.16 ETO24298.1 - 3 7.2 25.1 1.1 8.6 7.2 2.6 2 1 1 3 3 3 0 Intermediate filament protein ADIP PF11559.3 ETO24298.1 - 3.7 7.4 31.3 0.75 9.6 10.2 2.9 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding TSC22 PF01166.13 ETO24298.1 - 4 7.4 14.1 0.055 13.4 2.2 3.4 2 1 1 3 3 2 0 TSC-22/dip/bun family DUF489 PF04356.7 ETO24298.1 - 4.4 6.8 11.3 1.4 8.4 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF489) DUF1664 PF07889.7 ETO24298.1 - 4.6 7.0 17.2 0.14 11.9 2.2 2.9 3 1 0 3 3 2 0 Protein of unknown function (DUF1664) Kelch_6 PF13964.1 ETO24301.1 - 2.8e-09 36.7 1.1 0.0028 17.7 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 ETO24301.1 - 7.6e-05 22.1 6.0 0.042 13.4 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 ETO24301.1 - 0.0025 17.9 0.0 3.4 7.9 0.0 2.9 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO24301.1 - 0.032 14.0 6.0 2.3 8.1 0.1 3.8 3 0 0 3 3 3 0 Kelch motif Apis_Csd PF11671.3 ETO24302.1 - 0.74 9.5 9.9 1.4 8.6 6.9 1.4 1 0 0 1 1 1 0 Complementary sex determiner protein DAGAT PF03982.8 ETO24303.1 - 5.5e-22 77.8 0.0 8.7e-22 77.1 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol acyltransferase HSP70 PF00012.15 ETO24304.1 - 2.7e-33 114.7 11.6 3.2e-33 114.5 8.1 1.0 1 0 0 1 1 1 1 Hsp70 protein LMP PF04778.7 ETO24304.1 - 0.00031 20.5 9.9 0.00058 19.6 6.8 1.7 1 1 0 1 1 1 1 LMP repeated region DUF885 PF05960.6 ETO24304.1 - 0.01 15.0 5.3 0.011 14.8 3.7 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Bactofilin PF04519.8 ETO24304.1 - 0.069 13.1 0.4 0.15 12.0 0.2 1.6 1 1 0 1 1 1 0 Polymer-forming cytoskeletal Spc7 PF08317.6 ETO24304.1 - 0.25 9.9 5.3 0.3 9.6 3.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein HK97-gp10_like PF04883.7 ETO24304.1 - 1 10.3 4.8 0.57 11.1 0.6 2.4 1 1 1 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component Syja_N PF02383.13 ETO24307.1 - 1.4e-69 234.3 4.2 3.1e-67 226.6 2.9 2.7 1 1 0 1 1 1 1 SacI homology domain TP53IP5 PF15331.1 ETO24307.1 - 0.26 11.1 6.1 0.65 9.8 4.3 1.6 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 SIP1 PF04938.7 ETO24308.1 - 0.0061 15.9 0.0 0.011 15.1 0.0 1.4 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Nup35_RRM PF05172.8 ETO24309.1 - 0.081 12.6 1.0 3.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF2649 PF10854.3 ETO24310.1 - 0.25 11.4 3.8 2 8.5 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2649) DUF812 PF05667.6 ETO24313.1 - 4e-82 276.6 55.4 4e-82 276.6 38.4 2.9 1 1 1 2 2 2 1 Protein of unknown function (DUF812) EMP24_GP25L PF01105.19 ETO24313.1 - 0.015 15.0 4.8 0.015 15.0 3.3 5.1 3 2 1 4 4 3 0 emp24/gp25L/p24 family/GOLD Pox_A_type_inc PF04508.7 ETO24313.1 - 0.016 14.9 2.4 0.016 14.9 1.6 7.9 8 1 1 9 9 8 0 Viral A-type inclusion protein repeat AAA_27 PF13514.1 ETO24313.1 - 0.039 11.6 52.8 0.0058 14.4 32.9 1.8 1 1 1 2 2 2 0 AAA domain IncA PF04156.9 ETO24313.1 - 0.14 11.7 71.1 0.31 10.6 20.4 3.8 2 1 1 4 4 4 0 IncA protein Spc7 PF08317.6 ETO24313.1 - 0.32 9.6 69.0 0.026 13.1 17.0 3.8 1 1 1 3 3 3 0 Spc7 kinetochore protein NumbF PF06311.7 ETO24313.1 - 0.39 10.8 2.8 0.42 10.7 0.1 2.6 3 0 0 3 3 1 0 NUMB domain Reo_sigmaC PF04582.7 ETO24313.1 - 0.63 9.1 12.8 1.9 7.6 0.3 3.1 2 1 0 3 3 3 0 Reovirus sigma C capsid protein Allexi_40kDa PF05549.6 ETO24313.1 - 0.75 9.0 34.4 0.1 11.8 3.7 3.9 1 1 4 5 5 5 0 Allexivirus 40kDa protein T2SF PF00482.18 ETO24313.1 - 1.5 8.7 9.6 1.5 8.7 0.9 3.6 3 1 1 4 4 4 0 Type II secretion system (T2SS), protein F EzrA PF06160.7 ETO24313.1 - 3.1 5.8 57.8 2.4 6.2 26.3 2.7 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA HrpB7 PF09486.5 ETO24313.1 - 8.4 6.2 39.6 3.9 7.3 1.0 4.7 2 2 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) AAA_13 PF13166.1 ETO24313.1 - 8.8 4.6 67.3 0.91 7.9 24.1 3.3 1 1 1 2 2 2 0 AAA domain Syntaxin-6_N PF09177.6 ETO24313.1 - 8.9 6.7 52.4 0.22 11.9 2.7 6.6 1 1 6 7 7 7 0 Syntaxin 6, N-terminal FMN_dh PF01070.13 ETO24315.1 - 0.16 10.7 5.1 5 5.8 2.4 2.0 1 1 1 2 2 2 0 FMN-dependent dehydrogenase Rrn6 PF10214.4 ETO24315.1 - 0.19 9.7 10.2 0.2 9.6 7.0 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Peptidase_S64 PF08192.6 ETO24315.1 - 0.32 9.2 6.3 0.36 9.0 4.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 GAGA_bind PF06217.7 ETO24315.1 - 0.82 9.5 9.0 1 9.2 6.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Nop14 PF04147.7 ETO24315.1 - 0.88 7.4 15.3 1.1 7.1 10.6 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4551 PF15087.1 ETO24315.1 - 1.9 6.7 10.7 2.2 6.5 7.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Herpes_DNAp_acc PF04929.7 ETO24315.1 - 2.5 6.9 10.1 3.2 6.6 7.0 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Rox3 PF08633.5 ETO24315.1 - 4.9 7.4 10.6 32 4.7 6.1 2.0 1 1 1 2 2 2 0 Rox3 mediator complex subunit Suf PF05843.9 ETO24315.1 - 5.6 6.6 8.9 6.4 6.4 6.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DDHD PF02862.12 ETO24315.1 - 8 6.1 8.5 9.5 5.9 5.9 1.2 1 0 0 1 1 1 0 DDHD domain DUF1675 PF07897.6 ETO24315.1 - 8.2 6.1 11.9 10 5.8 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) VWA_3 PF13768.1 ETO24317.1 - 1.8e-13 50.4 0.0 2.9e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 ETO24317.1 - 3.1e-12 46.9 0.0 5.1e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 ETO24317.1 - 1.3e-10 41.3 0.0 2.1e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 ETO24317.1 - 2.2e-05 24.3 0.0 7.5e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 vWA found in TerF C terminus Copine PF07002.11 ETO24317.1 - 0.022 14.4 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Copine S1FA PF04689.8 ETO24317.1 - 0.11 12.4 0.9 0.31 10.9 0.3 1.9 2 0 0 2 2 2 0 DNA binding protein S1FA TPR_11 PF13414.1 ETO24318.1 - 7.3e-40 134.4 28.8 1.4e-09 37.4 0.1 8.1 6 1 3 9 9 9 9 TPR repeat TPR_1 PF00515.23 ETO24318.1 - 3.8e-37 124.3 33.2 8.7e-07 28.2 0.3 11.9 12 0 0 12 12 12 7 Tetratricopeptide repeat TPR_2 PF07719.12 ETO24318.1 - 7.2e-35 116.0 17.9 3.2e-05 23.5 0.0 10.8 12 0 0 12 12 11 7 Tetratricopeptide repeat TPR_12 PF13424.1 ETO24318.1 - 2.2e-28 98.0 16.1 8.5e-06 25.6 0.5 8.2 4 3 3 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.1 ETO24318.1 - 1.9e-23 80.3 3.2 0.0014 18.2 0.0 9.5 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 ETO24318.1 - 4.5e-23 81.3 7.8 7.7e-06 26.1 0.0 7.4 6 1 0 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.1 ETO24318.1 - 1e-22 78.9 9.3 0.026 14.9 0.0 10.6 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO24318.1 - 1.4e-19 68.3 27.5 0.03 14.1 0.0 11.8 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_16 PF13432.1 ETO24318.1 - 2.5e-19 69.4 0.0 5.7e-05 23.6 0.0 7.0 6 1 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO24318.1 - 3.6e-19 67.5 0.0 0.072 13.7 0.0 9.2 7 3 2 9 9 9 3 Tetratricopeptide repeat Apc3 PF12895.2 ETO24318.1 - 2.6e-17 62.7 35.9 9e-06 25.7 3.3 7.3 5 2 1 6 6 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 ETO24318.1 - 5.3e-07 29.3 3.2 0.095 12.6 0.0 7.1 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETO24318.1 - 2.6e-06 27.1 0.0 1.2 9.0 0.0 5.2 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO24318.1 - 4.2e-06 26.5 27.2 0.68 10.2 0.1 10.6 12 1 0 12 12 12 2 Tetratricopeptide repeat MIT PF04212.13 ETO24318.1 - 2.1e-05 24.3 14.0 0.93 9.4 0.0 6.8 8 1 0 8 8 7 2 MIT (microtubule interacting and transport) domain RPN7 PF10602.4 ETO24318.1 - 5.4e-05 22.6 2.1 0.049 13.0 0.2 3.8 2 1 0 2 2 2 1 26S proteasome subunit RPN7 Fis1_TPR_C PF14853.1 ETO24318.1 - 0.0012 18.6 3.1 15 5.5 0.1 4.8 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat NAAA-beta PF15508.1 ETO24318.1 - 0.22 11.8 3.0 2.7 8.3 0.0 3.7 4 0 0 4 4 4 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase TPR_21 PF09976.4 ETO24318.1 - 0.79 9.6 8.9 1.5 8.7 1.0 3.5 2 1 0 2 2 2 0 Tetratricopeptide repeat PPR_2 PF13041.1 ETO24318.1 - 2.9 7.9 9.7 47 4.0 0.0 5.2 5 0 0 5 5 5 0 PPR repeat family TPR_3 PF07720.7 ETO24318.1 - 5.3 6.9 27.9 0.46 10.3 0.7 6.8 7 1 0 7 7 7 0 Tetratricopeptide repeat Rhodanese PF00581.15 ETO24319.1 - 1.8e-08 34.7 0.0 2.8e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain LRR_4 PF12799.2 ETO24320.1 - 1.7e-21 75.3 49.3 2.1e-05 23.9 1.4 11.0 8 3 5 13 13 13 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETO24320.1 - 3.5e-17 59.7 42.0 0.23 11.6 0.0 17.3 18 0 0 18 18 18 3 Leucine Rich Repeat LRR_8 PF13855.1 ETO24320.1 - 1.8e-13 50.0 47.5 7.5e-05 22.4 0.1 9.6 6 2 5 11 11 11 8 Leucine rich repeat LRRNT_2 PF08263.7 ETO24320.1 - 4.2e-05 23.4 2.2 0.00015 21.6 1.5 2.1 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain DUF3338 PF11819.3 ETO24320.1 - 0.022 14.2 1.4 21 4.5 0.2 4.1 2 2 1 3 3 3 0 Domain of unknown function (DUF3338) LRR_7 PF13504.1 ETO24320.1 - 0.37 11.1 37.0 43 4.9 0.0 13.0 14 0 0 14 14 14 0 Leucine rich repeat DUF2115 PF09888.4 ETO24321.1 - 0.0034 17.5 2.2 0.0048 17.0 1.6 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2115) dNK PF01712.14 ETO24321.1 - 0.0068 16.3 0.3 0.014 15.2 0.2 1.6 1 1 0 1 1 1 1 Deoxynucleoside kinase CTD_bind PF04818.8 ETO24321.1 - 0.16 12.1 1.2 0.37 11.0 0.3 1.9 2 0 0 2 2 2 0 RNA polymerase II-binding domain. NDT80_PhoG PF05224.7 ETO24322.1 - 0.025 14.5 2.8 0.039 13.9 1.9 1.2 1 0 0 1 1 1 0 NDT80 / PhoG like DNA-binding family DUF4407 PF14362.1 ETO24322.1 - 0.067 12.1 8.9 0.095 11.6 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.4 ETO24322.1 - 0.43 9.4 13.3 0.59 9.0 9.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 RhoGAP PF00620.22 ETO24323.1 - 3.4e-16 59.2 0.0 6.3e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PBD PF00786.23 ETO24323.1 - 0.0016 18.7 0.0 0.0038 17.6 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain FA_desaturase PF00487.19 ETO24324.1 - 0.12 11.7 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 Fatty acid desaturase Borrelia_P83 PF05262.6 ETO24324.1 - 1.2 7.2 25.0 1.7 6.7 17.4 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein MIP-T3 PF10243.4 ETO24324.1 - 1.9 6.8 49.8 2.7 6.3 34.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PLRV_ORF5 PF01690.12 ETO24324.1 - 5.5 6.0 28.3 7.7 5.5 19.6 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Ctr PF04145.10 ETO24326.1 - 6.9e-21 74.8 1.1 6.9e-21 74.8 0.8 2.2 2 1 0 2 2 2 1 Ctr copper transporter family SAM_2 PF07647.12 ETO24329.1 - 3.1e-11 42.9 0.6 1.2e-09 37.8 0.1 2.7 2 1 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO24329.1 - 1e-09 38.3 0.3 2.3e-08 34.1 0.1 2.6 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DUF4551 PF15087.1 ETO24329.1 - 0.042 12.2 3.4 0.056 11.8 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Neur_chan_memb PF02932.11 ETO24329.1 - 0.35 10.7 1.3 0.5 10.2 0.9 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region WD40 PF00400.27 ETO24330.1 - 5.3e-18 64.1 8.3 3.3e-08 33.0 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat bZIP_1 PF00170.16 ETO24330.1 - 0.43 10.5 4.0 0.94 9.4 1.1 2.4 1 1 1 2 2 2 0 bZIP transcription factor SNARE PF05739.14 ETO24332.1 - 2.2e-16 59.3 3.4 2.2e-16 59.3 2.4 2.4 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 ETO24332.1 - 0.00035 20.6 11.1 0.00035 20.6 7.7 2.8 1 1 1 2 2 2 1 Syntaxin LMBR1 PF04791.11 ETO24332.1 - 0.0014 17.3 0.0 0.052 12.1 0.0 2.8 2 1 0 2 2 2 1 LMBR1-like membrane protein AATF-Che1 PF13339.1 ETO24332.1 - 0.6 10.2 16.1 0.12 12.5 5.4 2.9 3 0 0 3 3 3 0 Apoptosis antagonizing transcription factor Tfb2 PF03849.9 ETO24333.1 - 2.2e-82 276.6 5.9 1.6e-81 273.7 4.1 1.9 1 1 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 ETO24333.1 - 0.00024 20.8 0.0 0.00088 19.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Bunya_G2 PF03563.8 ETO24334.1 - 1.8 7.3 6.7 3.1 6.6 4.6 1.3 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 Gag_p17 PF00540.13 ETO24335.1 - 0.061 13.0 2.6 0.079 12.7 0.6 2.0 2 0 0 2 2 2 0 gag gene protein p17 (matrix protein) DUF2500 PF10694.4 ETO24335.1 - 0.24 11.3 2.7 1.1 9.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) LacI PF00356.16 ETO24336.1 - 0.18 11.4 0.1 0.33 10.6 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family PIP5K PF01504.13 ETO24338.1 - 5.1e-26 91.2 0.0 8.1e-26 90.6 0.0 1.3 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF4564 PF15169.1 ETO24338.1 - 0.0053 16.5 0.1 0.0095 15.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4564) RRM_1 PF00076.17 ETO24341.1 - 7.9e-05 22.2 0.0 0.00016 21.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO24341.1 - 0.0018 18.2 0.0 0.004 17.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1980 PF09323.5 ETO24342.1 - 0.36 10.5 0.0 0.36 10.5 0.0 6.2 4 1 3 7 7 7 0 Domain of unknown function (DUF1980) PIG-P PF08510.7 ETO24342.1 - 0.47 10.0 0.0 0.47 10.0 0.0 4.4 5 1 0 5 5 5 0 PIG-P DUF1948 PF09185.5 ETO24344.1 - 0.15 11.7 2.1 0.18 11.4 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1948) gp32 PF08804.5 ETO24344.1 - 0.17 12.0 2.5 0.25 11.4 1.8 1.4 1 1 0 1 1 1 0 gp32 DNA binding protein like EF-hand_7 PF13499.1 ETO24345.1 - 7.6e-06 25.9 2.1 0.00012 22.1 0.8 2.6 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO24345.1 - 0.00016 21.2 0.4 0.031 14.1 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 ETO24345.1 - 0.00029 19.9 1.2 0.0018 17.4 0.0 2.8 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.1 ETO24345.1 - 0.0021 17.3 0.1 0.0021 17.3 0.1 2.5 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 ETO24345.1 - 0.02 14.4 0.6 0.27 10.8 0.0 2.9 3 1 0 3 3 3 0 EF-hand domain pair SPARC_Ca_bdg PF10591.4 ETO24345.1 - 0.4 10.7 3.3 7.1 6.7 0.0 3.0 2 1 2 4 4 4 0 Secreted protein acidic and rich in cysteine Ca binding region Acyltransferase PF01553.16 ETO24346.1 - 3.3e-10 39.5 0.0 5.8e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Mnd1 PF03962.10 ETO24348.1 - 0.00066 19.3 35.9 0.0083 15.8 12.6 2.2 1 1 1 2 2 2 2 Mnd1 family HrpB7 PF09486.5 ETO24348.1 - 0.024 14.5 7.5 1.7 8.5 0.1 3.0 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) DUF869 PF05911.6 ETO24348.1 - 0.1 10.8 35.2 0.15 10.2 24.2 1.3 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) CENP-F_N PF10481.4 ETO24348.1 - 0.11 11.8 34.5 0.089 12.1 18.7 2.2 1 1 1 2 2 2 0 Cenp-F N-terminal domain Tropomyosin_1 PF12718.2 ETO24348.1 - 0.13 12.0 47.5 0.64 9.8 6.6 4.3 2 1 2 4 4 4 0 Tropomyosin like IncA PF04156.9 ETO24348.1 - 0.85 9.1 40.7 2.7 7.5 16.1 3.0 1 1 2 3 3 3 0 IncA protein DUF2553 PF10830.3 ETO24348.1 - 3.6 8.1 7.9 1.7 9.1 0.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2553) DUF4613 PF15390.1 ETO24348.1 - 4.3 5.3 21.7 5.2 5.1 15.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) AAA_13 PF13166.1 ETO24348.1 - 4.7 5.5 46.4 0.079 11.4 14.4 2.1 1 1 1 2 2 2 0 AAA domain CCDC155 PF14662.1 ETO24348.1 - 6.2 6.3 39.0 11 5.5 11.8 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Atg14 PF10186.4 ETO24348.1 - 6.4 5.6 37.7 0.061 12.2 9.8 2.8 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Mod_r PF07200.8 ETO24348.1 - 6.5 6.6 38.9 1.5 8.6 10.8 3.1 1 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein ADIP PF11559.3 ETO24348.1 - 7.4 6.4 46.8 0.09 12.6 11.1 3.6 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 ETO24348.1 - 8.1 6.3 39.8 2.3 8.0 12.5 3.7 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.3 ETO24348.1 - 9.2 3.4 37.2 1.4 6.1 11.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Baculo_LEF-2 PF03041.9 ETO24349.1 - 0.03 14.0 0.7 0.052 13.2 0.5 1.4 1 0 0 1 1 1 0 lef-2 rve_3 PF13683.1 ETO24349.1 - 0.038 13.5 0.2 14 5.2 0.0 3.6 3 1 1 4 4 4 0 Integrase core domain DUF3439 PF11921.3 ETO24351.1 - 5.5 6.7 9.8 19 5.0 6.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SAM_PNT PF02198.11 ETO24352.1 - 0.0012 18.5 0.2 0.0046 16.6 0.1 2.0 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain SAM_2 PF07647.12 ETO24352.1 - 0.06 13.2 1.1 0.15 11.8 0.2 2.2 2 1 0 2 2 2 0 SAM domain (Sterile alpha motif) DUF1533 PF07550.6 ETO24352.1 - 0.12 12.4 1.3 19 5.3 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1533) Laminin_G_3 PF13385.1 ETO24353.1 - 8.6e-06 26.0 0.0 2.1e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Beach PF02138.13 ETO24354.1 - 2.2e-99 332.3 4.5 2.2e-54 184.7 0.0 3.3 3 1 1 4 4 4 2 Beige/BEACH domain FYVE PF01363.16 ETO24354.1 - 4.5e-19 68.1 12.0 1.3e-18 66.6 8.3 1.8 1 0 0 1 1 1 1 FYVE zinc finger WD40 PF00400.27 ETO24354.1 - 3.3e-15 55.2 16.3 7.7e-09 35.1 0.3 5.6 4 1 0 4 4 4 3 WD domain, G-beta repeat PH_BEACH PF14844.1 ETO24354.1 - 3.3e-11 42.9 0.4 2.3e-10 40.2 0.1 2.6 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH IBR PF01485.16 ETO24354.1 - 0.047 13.5 9.4 0.14 12.0 6.5 1.8 1 0 0 1 1 1 0 IBR domain Peptidase_C98 PF15499.1 ETO24357.1 - 0.044 13.0 0.2 0.044 13.0 0.2 1.7 1 1 1 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF1510 PF07423.6 ETO24357.1 - 0.1 11.9 9.9 0.13 11.6 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) zf-C2H2_3 PF13878.1 ETO24357.1 - 0.24 11.0 3.0 0.71 9.4 2.1 1.8 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO PA26 PF04636.8 ETO24357.1 - 0.52 8.9 8.0 0.17 10.5 3.4 1.6 1 1 1 2 2 2 0 PA26 p53-induced protein (sestrin) Cut8_N PF14482.1 ETO24357.1 - 0.86 9.6 6.1 3 7.9 4.2 2.1 1 1 0 1 1 1 0 Cut8 proteasome-binding domain WD40 PF00400.27 ETO24358.1 - 2.8e-76 248.8 23.6 8.9e-12 44.4 0.5 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat DUF1258 PF06869.7 ETO24358.1 - 5.9e-06 25.5 1.8 0.28 10.2 0.1 4.6 1 1 3 5 5 5 4 Protein of unknown function (DUF1258) Cytochrom_D1 PF02239.11 ETO24358.1 - 0.0023 16.2 0.1 0.088 11.0 0.0 2.6 1 1 1 2 2 2 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO24358.1 - 0.66 8.6 11.5 0.93 8.1 0.0 4.5 2 1 1 4 4 4 0 Nup133 N terminal like WW PF00397.21 ETO24359.1 - 0.0021 17.9 0.8 0.0049 16.6 0.6 1.7 1 0 0 1 1 1 1 WW domain NTF2 PF02136.15 ETO24360.1 - 6e-06 26.6 4.5 0.0006 20.1 1.7 3.4 1 1 1 2 2 2 1 Nuclear transport factor 2 (NTF2) domain UBA_4 PF14555.1 ETO24360.1 - 0.046 13.2 0.1 0.16 11.5 0.1 1.9 1 0 0 1 1 1 0 UBA-like domain Neur_chan_memb PF02932.11 ETO24364.1 - 0.071 12.9 10.7 0.078 12.8 1.6 2.7 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CytochromB561_N PF09786.4 ETO24365.1 - 0.053 11.9 18.4 0.096 11.1 12.7 1.3 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF1631 PF07793.6 ETO24365.1 - 1.1 7.2 4.2 2 6.4 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Sec3_C PF09763.4 ETO24365.1 - 1.6 6.7 14.3 0.069 11.2 6.1 1.4 2 0 0 2 2 2 0 Exocyst complex component Sec3 SOBP PF15279.1 ETO24365.1 - 2.4 8.4 11.6 4.1 7.6 8.0 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Golgin_A5 PF09787.4 ETO24365.1 - 9.7 4.5 19.5 14 4.0 13.5 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 zf-TRAF PF02176.13 ETO24366.1 - 8e-06 26.1 1.1 8e-06 26.1 0.7 3.6 3 0 0 3 3 3 1 TRAF-type zinc finger DUF3169 PF11368.3 ETO24368.1 - 0.13 11.4 0.7 0.2 10.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF912 PF06024.7 ETO24368.1 - 0.47 10.5 7.8 0.051 13.6 2.0 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Ribonuclease_3 PF00636.21 ETO24368.1 - 0.7 10.3 3.8 0.58 10.6 0.7 2.3 3 0 0 3 3 3 0 Ribonuclease III domain Secretin_N_2 PF07655.8 ETO24368.1 - 1.2 9.5 19.0 0.81 10.1 8.2 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain Methyltransf_12 PF08242.7 ETO24368.1 - 1.2 9.6 4.2 1.1 9.7 1.4 2.1 2 0 0 2 2 2 0 Methyltransferase domain BAF1_ABF1 PF04684.8 ETO24368.1 - 5.1 5.8 13.4 0.02 13.7 2.7 1.6 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Pkinase PF00069.20 ETO24369.1 - 2.8e-55 187.2 0.0 2.1e-53 181.1 0.0 2.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO24369.1 - 1.9e-27 95.9 0.0 9.5e-26 90.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO24369.1 - 0.00057 19.0 0.1 0.0017 17.4 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETO24369.1 - 0.00094 18.2 0.0 0.0019 17.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 ETO24369.1 - 0.0049 16.6 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Clp1 PF06807.9 ETO24369.1 - 0.12 12.1 0.2 0.2 11.3 0.1 1.6 1 1 0 1 1 1 0 Pre-mRNA cleavage complex II protein Clp1 DUF87 PF01935.12 ETO24370.1 - 0.0051 16.6 0.9 0.006 16.4 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF87 NinG PF05766.7 ETO24371.1 - 0.009 15.7 1.2 0.014 15.1 0.8 1.3 1 0 0 1 1 1 1 Bacteriophage Lambda NinG protein P-mevalo_kinase PF04275.9 ETO24371.1 - 0.041 13.6 0.3 0.072 12.8 0.2 1.3 1 0 0 1 1 1 0 Phosphomevalonate kinase SSP160 PF06933.6 ETO24371.1 - 0.57 8.0 21.8 0.79 7.6 15.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.12 ETO24371.1 - 1.8 8.3 33.5 0.22 11.2 18.8 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF21 PF01595.15 ETO24372.1 - 4.2e-23 81.5 0.0 6.7e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 ETO24372.1 - 7.6e-05 22.4 0.0 0.05 13.3 0.0 3.2 3 0 0 3 3 3 2 CBS domain DUF1445 PF07286.7 ETO24374.1 - 6.1e-05 22.6 0.6 9.5e-05 22.0 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) DUF2270 PF10028.4 ETO24374.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2270) ATG_C PF09333.6 ETO24375.1 - 0.035 14.2 1.3 0.5 10.5 0.5 2.9 2 1 0 2 2 2 0 ATG C terminal domain Senescence PF06911.7 ETO24375.1 - 0.055 13.1 0.8 0.17 11.6 0.5 1.8 1 0 0 1 1 1 0 Senescence-associated protein DUF3414 PF11894.3 ETO24376.1 - 1.4e-17 62.0 2.2 1.8e-17 61.7 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Nop14 PF04147.7 ETO24377.1 - 0.14 10.0 21.6 0.17 9.8 15.0 1.0 1 0 0 1 1 1 0 Nop14-like family Menin PF05053.8 ETO24377.1 - 1.9 6.5 11.0 2.4 6.2 7.6 1.1 1 0 0 1 1 1 0 Menin Hid1 PF12722.2 ETO24377.1 - 4.3 4.8 12.9 5.4 4.5 8.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein VEGF_C PF14554.1 ETO24379.1 - 3.9 7.3 6.5 7.7 6.4 0.1 3.4 3 0 0 3 3 3 0 VEGF heparin-binding domain Kelch_6 PF13964.1 ETO24380.1 - 6.5e-08 32.4 4.0 0.037 14.2 0.1 4.0 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 ETO24380.1 - 4e-06 26.2 6.8 4.6e-05 22.8 0.0 3.5 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO24380.1 - 0.00011 22.3 0.2 0.0011 19.1 0.0 2.8 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO24380.1 - 0.00036 20.2 1.6 0.014 15.1 0.0 3.4 3 1 1 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO24380.1 - 0.038 13.9 1.5 12 5.9 0.1 3.7 4 0 0 4 4 4 0 Kelch motif Peptidase_C14 PF00656.17 ETO24381.1 - 2.5e-08 33.9 0.5 3.6e-08 33.4 0.3 1.2 1 0 0 1 1 1 1 Caspase domain UCH PF00443.24 ETO24381.1 - 0.093 11.8 0.4 0.15 11.1 0.3 1.4 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Hydant_A_N PF05378.8 ETO24382.1 - 0.18 11.3 2.2 0.25 10.8 1.5 1.4 1 1 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region RasGEF PF00617.14 ETO24383.1 - 5.9e-43 146.7 0.9 1.5e-42 145.4 0.6 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 ETO24383.1 - 3.7e-06 26.9 0.5 3.7e-06 26.9 0.4 2.8 2 1 0 2 2 2 1 RasGEF N-terminal motif Ninjurin PF04923.7 ETO24384.1 - 0.031 13.9 1.8 0.045 13.4 0.9 1.7 1 1 0 1 1 1 0 Ninjurin DUF3899 PF13038.1 ETO24384.1 - 0.036 14.2 0.4 0.036 14.2 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) DUF2839 PF10999.3 ETO24384.1 - 0.085 12.8 1.3 0.14 12.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) AhpC-TSA PF00578.16 ETO24385.1 - 0.0028 17.3 0.0 0.0049 16.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family HUN PF08729.5 ETO24385.1 - 0.055 13.3 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 HPC2 and ubinuclein domain Apt1 PF10351.4 ETO24386.1 - 0.65 8.7 24.0 0.27 10.0 6.9 2.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain GRP PF07172.6 ETO24386.1 - 1.7 9.1 0.0 1.7 9.1 0.0 3.3 4 0 0 4 4 4 0 Glycine rich protein family AIF_C PF14721.1 ETO24386.1 - 3.7 7.8 12.2 6.9 6.9 1.6 3.5 3 0 0 3 3 3 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF2140 PF09911.4 ETO24386.1 - 5.1 6.2 9.0 5 6.2 0.2 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2140) SR-25 PF10500.4 ETO24386.1 - 7.2 6.0 28.6 1.7 8.0 10.3 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Zip PF02535.17 ETO24387.1 - 4e-35 121.3 4.3 4.6e-35 121.1 3.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter TRIC PF05197.8 ETO24387.1 - 0.041 13.3 1.0 0.68 9.3 0.2 2.2 1 1 1 2 2 2 0 TRIC channel DUF2127 PF09900.4 ETO24387.1 - 0.066 13.2 4.1 0.13 12.3 2.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2127) YwiC PF14256.1 ETO24387.1 - 0.58 10.2 9.3 0.041 13.9 1.9 2.2 2 1 1 3 3 3 0 YwiC-like protein MA3 PF02847.12 ETO24389.1 - 0.032 13.9 0.3 0.23 11.1 0.1 2.4 2 0 0 2 2 2 0 MA3 domain TAFH PF07531.9 ETO24389.1 - 0.036 13.7 0.1 0.095 12.3 0.1 1.7 1 0 0 1 1 1 0 NHR1 homology to TAF Peptidase_S49_N PF08496.5 ETO24389.1 - 7.6 6.3 7.0 1.3 8.7 1.2 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal RGS PF00615.14 ETO24390.1 - 0.00072 19.6 0.7 0.0012 18.9 0.1 1.7 1 1 1 2 2 2 1 Regulator of G protein signaling domain Mem_trans PF03547.13 ETO24390.1 - 0.23 9.7 1.8 0.22 9.8 1.2 1.1 1 0 0 1 1 1 0 Membrane transport protein NAM-associated PF14303.1 ETO24390.1 - 0.47 10.7 20.1 0.82 9.9 13.9 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Daxx PF03344.10 ETO24390.1 - 1.5 7.1 26.1 1.8 6.9 18.1 1.1 1 0 0 1 1 1 0 Daxx Family SelP_N PF04592.9 ETO24390.1 - 6.2 6.1 11.8 9.2 5.5 8.2 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SAM_1 PF00536.25 ETO24392.1 - 0.0017 18.4 0.0 0.0028 17.8 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank_2 PF12796.2 ETO24393.1 - 2.4e-24 85.4 9.5 2.3e-06 27.8 0.0 4.3 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO24393.1 - 6.2e-18 64.4 6.9 0.0025 18.0 0.0 7.4 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO24393.1 - 5.2e-16 58.6 9.4 0.0001 22.6 0.0 6.2 4 2 3 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.25 ETO24393.1 - 1.3e-14 53.1 5.8 0.063 13.1 0.0 7.5 8 0 0 8 8 8 5 Ankyrin repeat Ank_3 PF13606.1 ETO24393.1 - 4.6e-07 29.4 5.8 0.23 11.8 0.0 6.6 6 0 0 6 6 6 1 Ankyrin repeat Replic_Relax PF13814.1 ETO24393.1 - 0.087 12.6 0.1 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Replication-relaxation AstE_AspA PF04952.9 ETO24394.1 - 1.5e-45 155.3 0.0 1.7e-45 155.1 0.0 1.0 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Peptidase_M14 PF00246.19 ETO24394.1 - 0.016 14.8 0.0 0.031 13.8 0.0 1.5 1 1 0 1 1 1 0 Zinc carboxypeptidase EF-hand_7 PF13499.1 ETO24396.1 - 0.00011 22.2 0.4 0.49 10.5 0.0 2.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.1 ETO24396.1 - 0.0014 18.1 0.7 1.6 8.4 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 ETO24396.1 - 0.0071 15.5 3.8 1.3 8.4 0.0 3.9 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.1 ETO24396.1 - 0.19 11.7 0.3 28 4.9 0.0 3.4 3 0 0 3 3 3 0 EF-hand domain Chordopox_A13L PF05961.6 ETO24396.1 - 1 9.3 7.9 1.6 8.7 3.9 2.3 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Kinesin PF00225.18 ETO24397.1 - 2.9e-41 141.2 0.0 3.1e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Atg31 PF09795.4 ETO24398.1 - 3.6 7.2 7.6 5.2 6.7 5.2 1.3 1 0 0 1 1 1 0 Autophagy-related protein 31 DUF3595 PF12166.3 ETO24399.1 - 9.3e-36 123.5 0.3 1.1e-35 123.2 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3595) Peptidase_S28 PF05577.7 ETO24400.1 - 6.7e-71 239.1 3.0 8.1e-71 238.8 2.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 DUF2920 PF11144.3 ETO24400.1 - 0.0029 16.6 0.0 0.0047 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Abhydrolase_6 PF12697.2 ETO24400.1 - 0.093 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Cullin_Nedd8 PF10557.4 ETO24401.1 - 2.1e-27 94.7 3.2 4.5e-27 93.6 2.2 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain Cullin PF00888.17 ETO24401.1 - 2.4e-08 32.9 1.8 3.2e-08 32.5 0.1 1.8 2 0 0 2 2 2 1 Cullin family Penicillinase_R PF03965.11 ETO24401.1 - 0.029 14.4 0.1 0.075 13.1 0.0 1.7 2 0 0 2 2 2 0 Penicillinase repressor DUF3658 PF12395.3 ETO24401.1 - 0.095 12.2 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function Cullin PF00888.17 ETO24402.1 - 2e-21 76.1 4.3 2.4e-21 75.9 2.9 1.0 1 0 0 1 1 1 1 Cullin family Telomerase_RBD PF12009.3 ETO24402.1 - 0.086 12.7 0.1 0.18 11.7 0.0 1.4 1 1 0 1 1 1 0 Telomerase ribonucleoprotein complex - RNA binding domain Methyltransf_3 PF01596.12 ETO24403.1 - 7.1e-27 93.7 0.1 1e-26 93.2 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 ETO24403.1 - 4.1e-05 24.3 0.0 8e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO24403.1 - 0.00022 21.7 0.0 0.00031 21.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETO24403.1 - 0.04 14.4 0.0 0.074 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 ETO24403.1 - 0.041 12.9 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 ETO24403.1 - 0.061 12.9 0.1 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Chordopox_G2 PF05796.7 ETO24403.1 - 0.082 12.0 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Chordopoxvirus protein G2 GCD14 PF08704.5 ETO24403.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.5 1 1 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit ELMO_CED12 PF04727.8 ETO24407.1 - 8.6e-16 57.9 2.8 2.5e-15 56.4 2.0 2.0 1 1 0 1 1 1 1 ELMO/CED-12 family P5-ATPase PF12409.3 ETO24407.1 - 0.076 12.8 3.0 0.33 10.7 0.0 2.7 2 0 0 2 2 2 0 P5-type ATPase cation transporter EF-hand_6 PF13405.1 ETO24410.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain H_PPase PF03030.11 ETO24411.1 - 2.4e-24 85.6 9.5 7.1e-23 80.7 6.6 2.1 1 1 0 1 1 1 1 Inorganic H+ pyrophosphatase DUF4282 PF14110.1 ETO24411.1 - 0.37 11.0 0.1 0.37 11.0 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4282) DUF4064 PF13273.1 ETO24411.1 - 4.3 7.5 17.0 0.35 10.9 3.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Ribosomal_60s PF00428.14 ETO24412.1 - 3.3 8.1 25.9 4.2 7.8 0.3 3.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein HSP70 PF00012.15 ETO24413.1 - 0.00018 19.5 0.0 0.00091 17.2 0.0 1.8 1 1 0 1 1 1 1 Hsp70 protein Peptidase_M22 PF00814.20 ETO24413.1 - 0.01 15.3 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 0 Glycoprotease family INCENP_ARK-bind PF03941.10 ETO24413.1 - 0.012 15.4 0.5 0.024 14.4 0.1 1.7 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region PhoD PF09423.5 ETO24414.1 - 0.0041 15.7 0.0 0.012 14.1 0.0 1.7 1 1 0 1 1 1 1 PhoD-like phosphatase TMEM154 PF15102.1 ETO24414.1 - 0.011 15.4 1.0 0.026 14.2 0.7 1.6 1 0 0 1 1 1 0 TMEM154 protein family DUF912 PF06024.7 ETO24414.1 - 0.03 14.3 4.3 0.03 14.3 3.0 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) UPF0697 PF15117.1 ETO24414.1 - 0.078 12.7 0.2 0.078 12.7 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0697 DUF3688 PF12461.3 ETO24414.1 - 0.081 13.3 7.8 0.78 10.1 4.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3688) EphA2_TM PF14575.1 ETO24414.1 - 0.12 12.7 0.5 0.5 10.7 0.4 2.0 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain 7TM-7TMR_HD PF07698.6 ETO24414.1 - 0.89 8.9 13.2 5.1 6.4 6.2 2.9 1 1 2 3 3 3 0 7TM receptor with intracellular HD hydrolase Ly49 PF08391.5 ETO24414.1 - 4.4 7.4 8.1 0.23 11.5 1.1 2.2 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region Tim17 PF02466.14 ETO24415.1 - 5.9e-05 23.1 0.1 9.9e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF2109 PF09882.4 ETO24415.1 - 0.12 12.3 0.2 0.74 9.8 0.0 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) SH2_2 PF14633.1 ETO24416.1 - 0.0089 15.1 0.1 0.013 14.5 0.1 1.3 1 0 0 1 1 1 1 SH2 domain Macoilin PF09726.4 ETO24416.1 - 4.2 5.5 14.2 5.1 5.2 9.8 1.0 1 0 0 1 1 1 0 Transmembrane protein Nop14 PF04147.7 ETO24417.1 - 0.15 9.9 10.9 0.17 9.7 7.6 1.0 1 0 0 1 1 1 0 Nop14-like family PIG-S PF10510.4 ETO24417.1 - 0.58 8.7 7.9 0.63 8.6 5.5 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein Daxx PF03344.10 ETO24417.1 - 1.4 7.3 12.8 1.7 6.9 8.9 1.2 1 0 0 1 1 1 0 Daxx Family SEEEED PF14797.1 ETO24417.1 - 2.7 8.1 15.1 3.7 7.6 10.5 1.1 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex Neur_chan_memb PF02932.11 ETO24417.1 - 3.8 7.3 8.5 4.9 6.9 5.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region eIF-3c_N PF05470.7 ETO24417.1 - 3.9 5.4 9.8 4.2 5.3 6.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCYCGC PF13798.1 ETO24417.1 - 5.9 6.5 7.2 1.7 8.3 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function with PCYCGC motif YL1 PF05764.8 ETO24417.1 - 6 6.4 16.9 7.9 6.0 11.7 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Ly49 PF08391.5 ETO24417.1 - 6.8 6.8 7.4 9.1 6.4 5.2 1.1 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF605 PF04652.11 ETO24417.1 - 9.1 5.5 14.6 10 5.3 10.2 1.0 1 0 0 1 1 1 0 Vta1 like Lipoxygenase PF00305.14 ETO24418.1 - 0.00046 18.3 0.0 0.00064 17.8 0.0 1.2 1 0 0 1 1 1 1 Lipoxygenase YGGT PF02325.12 ETO24418.1 - 0.0064 16.4 0.1 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 YGGT family GTP_EFTU PF00009.22 ETO24419.1 - 0.0029 17.0 0.0 0.0055 16.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Bac_DnaA_C PF08299.6 ETO24419.1 - 0.11 12.3 0.2 0.29 11.0 0.1 1.7 1 0 0 1 1 1 0 Bacterial dnaA protein helix-turn-helix Xpo1 PF08389.7 ETO24420.1 - 5.3e-12 45.8 1.0 5.3e-12 45.8 0.7 3.0 3 0 0 3 3 3 1 Exportin 1-like protein LrgB PF04172.11 ETO24421.1 - 0.035 13.2 1.3 0.58 9.2 0.1 2.0 1 1 1 2 2 2 0 LrgB-like family DUF1084 PF06454.6 ETO24421.1 - 0.043 12.8 0.6 0.051 12.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1084) EamA PF00892.15 ETO24421.1 - 0.13 12.2 7.8 0.22 11.5 5.4 1.3 1 0 0 1 1 1 0 EamA-like transporter family DUF4149 PF13664.1 ETO24421.1 - 0.31 11.1 4.8 0.43 10.6 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) DUF485 PF04341.7 ETO24421.1 - 0.67 9.7 3.3 0.88 9.3 1.9 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF485 ELM2 PF01448.19 ETO24423.1 - 1.3e-06 28.9 0.1 3.6e-06 27.5 0.1 1.7 1 0 0 1 1 1 1 ELM2 domain ARID PF01388.16 ETO24423.1 - 0.016 15.0 0.1 0.041 13.7 0.0 1.8 1 0 0 1 1 1 0 ARID/BRIGHT DNA binding domain Bombinin PF05298.6 ETO24424.1 - 0.036 13.5 2.5 0.047 13.1 1.8 1.1 1 0 0 1 1 1 0 Bombinin BDV_P24 PF06595.6 ETO24424.1 - 0.068 12.9 3.6 0.083 12.6 2.5 1.1 1 0 0 1 1 1 0 Borna disease virus P24 protein Baculo_PEP_C PF04513.7 ETO24424.1 - 0.4 10.5 5.3 7.8 6.3 0.1 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF919 PF06034.6 ETO24424.1 - 0.43 10.2 17.0 0.079 12.5 3.8 3.4 2 1 2 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DUF4239 PF14023.1 ETO24424.1 - 0.45 9.8 4.4 0.98 8.7 3.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) DNA_Packaging PF11053.3 ETO24424.1 - 0.49 10.0 7.6 0.66 9.5 5.3 1.2 1 0 0 1 1 1 0 Terminase DNA packaging enzyme PEP-utilisers_N PF05524.8 ETO24424.1 - 0.51 10.1 3.9 0.83 9.4 2.7 1.6 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal RtcB PF01139.12 ETO24424.1 - 0.74 8.7 4.2 0.34 9.8 1.4 1.5 1 1 1 2 2 2 0 tRNA-splicing ligase RtcB Membralin PF09746.4 ETO24424.1 - 1 8.3 7.3 1.1 8.1 5.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein RRF PF01765.14 ETO24424.1 - 1.2 8.5 12.5 1.2 8.5 7.4 2.0 1 1 1 2 2 2 0 Ribosome recycling factor DUF2229 PF09989.4 ETO24424.1 - 1.2 8.5 10.1 0.21 11.0 3.1 1.9 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF883 PF05957.8 ETO24424.1 - 1.3 9.5 5.1 9.3 6.7 0.7 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) VASP_tetra PF08776.6 ETO24424.1 - 1.6 8.0 9.2 0.35 10.2 0.3 2.8 3 0 0 3 3 3 0 VASP tetramerisation domain OmpH PF03938.9 ETO24424.1 - 3 7.7 23.2 65 3.4 16.1 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.1 ETO24424.1 - 3.2 6.6 8.6 3.8 6.3 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.10 ETO24424.1 - 6.1 5.9 13.5 7.4 5.6 9.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2203 PF09969.4 ETO24424.1 - 6.1 7.0 11.1 8.5 6.6 1.2 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF4065 PF13274.1 ETO24424.1 - 6.7 7.4 8.2 11 6.7 5.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4065) Phage_Mu_Gam PF07352.7 ETO24424.1 - 7.2 6.1 18.6 1.7e+03 -1.6 12.9 2.2 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein FliD_C PF07195.7 ETO24424.1 - 8.3 5.6 12.3 4.2 6.6 4.8 1.9 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF342 PF03961.8 ETO24424.1 - 9.2 4.5 13.3 11 4.2 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Peptidase_C65 PF10275.4 ETO24425.1 - 2.7e-48 164.4 1.1 4.5e-46 157.1 0.7 2.2 1 1 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 ETO24425.1 - 1.3e-08 35.4 1.1 0.0011 19.4 0.0 2.9 2 1 1 3 3 3 2 OTU-like cysteine protease DUF3848 PF12959.2 ETO24425.1 - 0.077 12.9 0.3 0.35 10.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3848) VWA PF00092.23 ETO24426.1 - 0.00019 21.1 0.1 0.0013 18.4 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain RRP14 PF15459.1 ETO24426.1 - 3.9 7.6 0.0 3.9 7.6 0.0 2.4 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 7TMR-DISM_7TM PF07695.6 ETO24427.1 - 0.1 12.2 15.9 0.071 12.7 5.1 2.5 2 1 0 2 2 2 0 7TM diverse intracellular signalling TPR_11 PF13414.1 ETO24428.1 - 3.7e-13 48.9 0.3 3.9e-08 32.8 0.0 3.6 2 1 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 ETO24428.1 - 5.7e-12 44.7 1.2 0.0068 15.9 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO24428.1 - 6.1e-10 38.2 0.1 0.016 15.0 0.0 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO24428.1 - 1.2e-05 24.7 0.6 0.13 12.1 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO24428.1 - 4.3e-05 23.3 0.2 0.1 12.5 0.1 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO24428.1 - 0.00037 20.4 0.1 0.037 14.2 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO24428.1 - 0.00099 19.4 1.0 0.012 15.8 0.0 3.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO24428.1 - 0.0017 18.9 0.0 2 9.1 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO24428.1 - 0.0032 17.9 0.0 3.9 8.3 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO24428.1 - 0.0033 17.1 0.0 0.58 10.0 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO24428.1 - 0.0075 16.3 0.0 0.046 13.8 0.0 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TcpE PF12648.2 ETO24432.1 - 0.00057 20.0 2.9 0.00069 19.7 2.0 1.1 1 0 0 1 1 1 1 TcpE family Nodulin-like PF06813.8 ETO24432.1 - 0.016 14.4 2.5 0.018 14.2 1.7 1.0 1 0 0 1 1 1 0 Nodulin-like COX2_TM PF02790.10 ETO24432.1 - 0.14 12.1 4.2 0.18 11.7 2.9 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain Fumarate_red_C PF02300.12 ETO24432.1 - 0.17 11.7 3.9 0.2 11.5 2.7 1.1 1 0 0 1 1 1 0 Fumarate reductase subunit C zf-DHHC PF01529.15 ETO24432.1 - 0.38 10.1 8.5 0.45 9.8 5.9 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF3377 PF11857.3 ETO24432.1 - 0.62 9.7 7.3 0.2 11.3 2.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3377) DUF3753 PF12575.3 ETO24432.1 - 0.62 9.8 13.9 0.26 11.1 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3753) DUF962 PF06127.6 ETO24432.1 - 4.5 7.2 5.4 13 5.7 3.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF962) EphA2_TM PF14575.1 ETO24432.1 - 6.1 7.3 5.8 4.4 7.7 0.6 2.1 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain BPD_transp_1 PF00528.17 ETO24432.1 - 7.7 5.9 8.3 2.8 7.4 0.5 2.0 1 1 1 2 2 2 0 Binding-protein-dependent transport system inner membrane component DUF3923 PF13061.1 ETO24432.1 - 9.8 6.1 10.2 1.3 8.8 3.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3923) Cortex-I_coil PF09304.5 ETO24433.1 - 0.00022 21.1 10.7 0.00026 20.9 7.4 1.2 1 0 0 1 1 1 1 Cortexillin I, coiled coil Filament PF00038.16 ETO24433.1 - 0.022 14.2 9.5 0.025 14.0 6.6 1.1 1 0 0 1 1 1 0 Intermediate filament protein Med22 PF06179.7 ETO24433.1 - 0.077 13.0 5.0 0.13 12.2 3.5 1.4 1 0 0 1 1 1 0 Surfeit locus protein 5 subunit 22 of Mediator complex APG6 PF04111.7 ETO24433.1 - 0.079 11.9 14.7 0.087 11.8 10.2 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 ETO24433.1 - 0.089 12.3 14.4 0.098 12.2 10.0 1.1 1 0 0 1 1 1 0 IncA protein Fmp27_WPPW PF10359.4 ETO24433.1 - 0.14 10.5 11.1 0.16 10.3 7.7 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain CENP-Q PF13094.1 ETO24433.1 - 0.2 11.7 10.4 0.24 11.4 7.2 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TMPIT PF07851.8 ETO24433.1 - 0.26 10.3 8.6 0.3 10.1 5.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein FlxA PF14282.1 ETO24433.1 - 0.31 11.0 15.6 0.74 9.7 10.0 1.9 1 1 0 1 1 1 0 FlxA-like protein Spc7 PF08317.6 ETO24433.1 - 0.32 9.5 14.2 0.37 9.4 9.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.7 ETO24433.1 - 0.42 10.3 14.8 0.75 9.5 10.3 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 ETO24433.1 - 0.44 9.4 13.3 0.59 9.0 9.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 EMP24_GP25L PF01105.19 ETO24433.1 - 0.53 9.9 3.1 0.77 9.4 2.1 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD ATG16 PF08614.6 ETO24433.1 - 0.55 10.0 13.3 3.3 7.4 9.2 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Prefoldin PF02996.12 ETO24433.1 - 0.7 9.5 11.6 0.76 9.4 1.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit TBPIP PF07106.8 ETO24433.1 - 0.74 9.3 12.3 1 8.9 8.5 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DASH_Dad3 PF08656.5 ETO24433.1 - 0.82 9.4 6.3 4.4 7.0 4.4 2.1 1 1 0 1 1 1 0 DASH complex subunit Dad3 zf-C4H2 PF10146.4 ETO24433.1 - 0.87 9.5 8.5 0.95 9.4 5.9 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein AAA_13 PF13166.1 ETO24433.1 - 1.1 7.6 10.8 1.4 7.3 7.5 1.2 1 0 0 1 1 1 0 AAA domain THOC7 PF05615.8 ETO24433.1 - 1.2 9.3 12.8 4.2 7.6 8.8 1.7 1 1 0 1 1 1 0 Tho complex subunit 7 DUF4094 PF13334.1 ETO24433.1 - 1.3 9.4 5.8 0.99 9.8 2.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) TMF_DNA_bd PF12329.3 ETO24433.1 - 1.6 8.5 19.3 11 5.8 11.6 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 ETO24433.1 - 1.6 9.0 8.0 2.3 8.6 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) AATF-Che1 PF13339.1 ETO24433.1 - 1.9 8.6 11.3 5.5 7.1 7.9 1.8 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF2018 PF09442.5 ETO24433.1 - 1.9 9.1 6.5 11 6.7 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2018) NPV_P10 PF05531.7 ETO24433.1 - 2.1 8.6 6.4 70 3.7 4.4 2.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein CENP-H PF05837.7 ETO24433.1 - 2.7 8.1 11.0 4.8 7.4 7.4 1.7 1 1 0 1 1 1 0 Centromere protein H (CENP-H) DUF4407 PF14362.1 ETO24433.1 - 3.1 6.6 9.5 4.3 6.2 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sec2p PF06428.6 ETO24433.1 - 3.2 7.6 12.0 85 3.0 8.3 2.2 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p Cep57_MT_bd PF06657.8 ETO24433.1 - 3.3 7.7 8.8 0.81 9.6 3.8 1.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Syntaxin-6_N PF09177.6 ETO24433.1 - 4 7.8 9.3 9 6.7 6.3 1.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF342 PF03961.8 ETO24433.1 - 5.1 5.3 10.8 5.9 5.1 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1664 PF07889.7 ETO24433.1 - 5.2 6.8 7.0 5.5 6.7 4.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.14 ETO24433.1 - 5.3 4.7 7.7 6 4.5 5.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ADIP PF11559.3 ETO24433.1 - 6.5 6.6 15.1 8.1 6.3 9.8 1.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Exonuc_VII_L PF02601.10 ETO24433.1 - 8.3 5.5 10.0 9.5 5.3 6.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ASFV_J13L PF05568.6 ETO24434.1 - 0.018 14.5 0.7 4.5 6.7 0.0 2.6 1 1 1 2 2 2 0 African swine fever virus J13L protein Shisa PF13908.1 ETO24434.1 - 0.052 13.7 0.1 0.052 13.7 0.1 2.2 2 2 0 2 2 2 0 Wnt and FGF inhibitory regulator CoA_binding_3 PF13727.1 ETO24434.1 - 0.091 12.5 0.3 0.35 10.6 0.0 1.9 1 1 1 2 2 2 0 CoA-binding domain EphA2_TM PF14575.1 ETO24435.1 - 2.5 8.5 0.0 2.5 8.5 0.0 3.3 3 1 1 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain Peptidase_C48 PF02902.14 ETO24435.1 - 3.6 7.1 9.2 0.11 12.0 0.3 2.2 2 0 0 2 2 2 0 Ulp1 protease family, C-terminal catalytic domain GCD14 PF08704.5 ETO24436.1 - 3.7e-79 265.7 5.4 8e-43 146.6 0.0 3.2 1 1 2 3 3 3 3 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 ETO24436.1 - 0.00017 21.2 1.4 0.0018 17.9 0.9 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO24436.1 - 0.00022 21.8 0.0 0.0009 19.8 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Suf PF05843.9 ETO24436.1 - 0.00055 19.7 10.7 0.001 18.8 7.4 1.6 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) PAT1 PF09770.4 ETO24436.1 - 0.018 13.2 41.3 0.029 12.6 28.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MTS PF05175.9 ETO24436.1 - 0.036 13.4 0.0 0.087 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain DUF605 PF04652.11 ETO24436.1 - 0.12 11.7 23.8 0.23 10.8 16.5 1.4 1 0 0 1 1 1 0 Vta1 like DUF822 PF05687.8 ETO24436.1 - 0.17 12.2 6.7 99 3.2 6.9 2.4 2 0 0 2 2 2 0 Plant protein of unknown function (DUF822) Ctr PF04145.10 ETO24436.1 - 0.33 11.0 6.1 41 4.2 0.0 2.6 2 0 0 2 2 2 0 Ctr copper transporter family TFIIA PF03153.8 ETO24436.1 - 0.8 9.5 28.3 0.027 14.4 15.6 1.5 2 0 0 2 2 1 0 Transcription factor IIA, alpha/beta subunit Spc7_N PF15402.1 ETO24436.1 - 0.86 7.5 14.2 1.5 6.7 9.9 1.3 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Tim54 PF11711.3 ETO24436.1 - 5.9 5.3 14.0 0.52 8.8 6.2 1.7 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Pap_E4 PF02711.9 ETO24436.1 - 9 7.1 22.1 17 6.3 11.5 2.5 2 0 0 2 2 2 0 E4 protein Ank_2 PF12796.2 ETO24437.1 - 0.053 13.8 0.1 0.12 12.7 0.1 1.7 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.25 ETO24437.1 - 0.1 12.4 0.1 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeat RGS PF00615.14 ETO24438.1 - 1.1e-09 38.3 1.2 1.3e-08 34.9 0.3 2.5 2 0 0 2 2 2 1 Regulator of G protein signaling domain GAGA_bind PF06217.7 ETO24440.1 - 0.25 11.2 4.5 0.31 10.9 3.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF573 PF04504.9 ETO24440.1 - 1.1 9.5 5.9 0.24 11.6 1.4 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF573 BBS2_Mid PF14783.1 ETO24441.1 - 0.041 13.6 0.0 0.18 11.5 0.0 2.2 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region XkdW PF09636.5 ETO24441.1 - 0.07 13.0 0.9 0.15 11.9 0.6 1.5 1 0 0 1 1 1 0 XkdW protein DUF3817 PF12823.2 ETO24445.1 - 3.5 8.1 13.4 0.55 10.7 3.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3817) WD40 PF00400.27 ETO24446.1 - 2.1e-79 258.8 23.6 3.8e-13 48.7 0.1 7.4 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO24446.1 - 2e-11 43.9 0.2 0.00031 20.5 0.0 3.3 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO24446.1 - 7.1e-08 31.0 8.5 0.029 12.5 0.1 4.6 1 1 1 3 3 3 2 Nucleoporin Nup120/160 PD40 PF07676.7 ETO24446.1 - 4.8e-05 22.9 10.6 6.2 6.6 0.0 6.0 6 0 0 6 6 6 3 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO24446.1 - 7.2e-05 22.3 1.1 0.00085 18.8 0.7 2.9 1 1 0 1 1 1 1 PQQ-like domain Nbas_N PF15492.1 ETO24446.1 - 0.00023 20.3 1.4 1.4 7.9 0.0 3.6 1 1 3 4 4 4 2 Neuroblastoma-amplified sequence, N terminal SGL PF08450.7 ETO24446.1 - 0.0014 18.0 0.7 0.0075 15.6 0.1 2.1 1 1 1 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Cytochrom_D1 PF02239.11 ETO24446.1 - 0.0063 14.8 0.9 0.87 7.8 0.1 2.9 1 1 3 4 4 4 3 Cytochrome D1 heme domain Resistin PF06954.6 ETO24446.1 - 0.016 15.4 3.2 11 6.3 0.0 4.1 2 2 2 4 4 4 0 Resistin DUF1797 PF08796.5 ETO24446.1 - 0.042 13.7 0.0 4.6 7.1 0.0 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1797) Proteasome_A_N PF10584.4 ETO24446.1 - 0.087 12.1 3.5 20 4.6 0.0 4.4 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature SET PF00856.23 ETO24447.1 - 2.7e-06 27.7 0.6 0.00012 22.4 0.0 2.8 2 1 0 2 2 2 1 SET domain MORN PF02493.15 ETO24447.1 - 0.22 11.3 3.2 3.5 7.5 0.7 2.9 2 0 0 2 2 2 0 MORN repeat Chordopox_A13L PF05961.6 ETO24448.1 - 0.13 12.2 1.1 0.4 10.6 0.0 2.3 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Prefoldin_2 PF01920.15 ETO24449.1 - 3.6e-10 39.5 3.6 3.6e-10 39.5 2.5 2.2 1 1 1 2 2 2 1 Prefoldin subunit ADIP PF11559.3 ETO24449.1 - 0.0025 17.7 11.5 0.064 13.1 4.9 2.1 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 ETO24449.1 - 0.017 14.9 16.0 0.28 11.0 11.1 2.1 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 ETO24449.1 - 0.023 14.3 9.4 0.091 12.3 2.1 2.1 2 0 0 2 2 2 0 IncA protein Reo_sigmaC PF04582.7 ETO24449.1 - 0.029 13.5 0.8 0.036 13.2 0.5 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF724 PF05266.9 ETO24449.1 - 0.037 13.6 11.2 0.14 11.7 4.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) TBPIP PF07106.8 ETO24449.1 - 0.038 13.5 8.7 0.19 11.2 2.1 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NPV_P10 PF05531.7 ETO24449.1 - 0.038 14.2 0.3 0.038 14.2 0.2 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2968 PF11180.3 ETO24449.1 - 0.051 12.9 2.5 0.067 12.5 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Osmo_CC PF08946.5 ETO24449.1 - 0.053 13.5 0.8 0.053 13.5 0.6 2.5 2 1 0 2 2 2 0 Osmosensory transporter coiled coil Laminin_II PF06009.7 ETO24449.1 - 0.067 12.9 9.3 0.77 9.5 0.3 2.4 2 1 0 2 2 2 0 Laminin Domain II AFT PF08731.6 ETO24449.1 - 0.075 13.2 4.4 0.11 12.6 3.0 1.6 1 1 0 1 1 1 0 Transcription factor AFT Cob_adeno_trans PF01923.13 ETO24449.1 - 0.076 12.7 3.8 0.1 12.4 1.0 1.9 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DegS PF05384.6 ETO24449.1 - 0.12 11.6 8.0 3 7.0 1.9 2.5 2 1 0 2 2 2 0 Sensor protein DegS NiFeSe_Hases PF00374.14 ETO24449.1 - 0.18 10.5 3.1 1.5 7.5 0.8 2.0 1 1 1 2 2 2 0 Nickel-dependent hydrogenase DUF3450 PF11932.3 ETO24449.1 - 0.19 10.9 5.7 0.21 10.7 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) T2SJ PF11612.3 ETO24449.1 - 0.2 11.4 1.6 1.2 8.8 0.3 2.1 1 1 0 2 2 2 0 Type II secretion system (T2SS), protein J Flagellar_rod PF05149.7 ETO24449.1 - 0.27 10.3 9.9 0.5 9.5 0.4 2.0 2 0 0 2 2 2 0 Paraflagellar rod protein Snapin_Pallidin PF14712.1 ETO24449.1 - 0.28 11.5 0.2 0.28 11.5 0.1 2.8 2 1 0 3 3 3 0 Snapin/Pallidin TPR_MLP1_2 PF07926.7 ETO24449.1 - 0.72 9.5 11.5 0.77 9.5 3.9 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.7 ETO24449.1 - 0.77 9.5 7.8 5.5 6.7 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Nsp1_C PF05064.8 ETO24449.1 - 0.95 9.1 6.6 7.1 6.3 0.2 2.1 2 0 0 2 2 2 0 Nsp1-like C-terminal region DUF4140 PF13600.1 ETO24449.1 - 0.99 9.8 4.6 20 5.6 1.7 2.5 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Streptin-Immun PF11083.3 ETO24449.1 - 1 9.3 7.8 2.8 7.9 1.3 2.4 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein CENP-Q PF13094.1 ETO24449.1 - 1.1 9.2 9.0 1.7 8.6 6.2 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF972 PF06156.8 ETO24449.1 - 1.2 9.5 11.8 6.8 7.0 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 ETO24449.1 - 1.3 6.7 11.8 0.55 8.0 0.8 2.0 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family GAS PF13851.1 ETO24449.1 - 1.3 8.1 16.5 3.1 6.9 6.1 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF310 PF03750.8 ETO24449.1 - 2.3 8.4 6.2 1.2 9.3 1.2 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF310) DivIC PF04977.10 ETO24449.1 - 2.9 7.4 9.0 12 5.4 3.3 2.3 2 0 0 2 2 2 0 Septum formation initiator Syntaxin-6_N PF09177.6 ETO24449.1 - 3.2 8.2 7.1 12 6.3 1.3 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Wbp11 PF09429.5 ETO24449.1 - 3.2 7.7 15.8 21 5.2 7.8 2.5 2 1 0 2 2 2 0 WW domain binding protein 11 DUF1090 PF06476.7 ETO24449.1 - 4 7.1 11.1 1.4 8.5 3.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) APG6 PF04111.7 ETO24449.1 - 4.9 6.1 13.8 5.4 5.9 0.4 2.0 1 1 0 2 2 2 0 Autophagy protein Apg6 DUF4200 PF13863.1 ETO24449.1 - 6.1 6.8 15.6 8.6 6.3 0.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) ING PF12998.2 ETO24449.1 - 6.4 7.1 10.3 9.5 6.5 0.2 2.9 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding WD40 PF00400.27 ETO24450.1 - 1.6e-56 186.2 25.8 4.5e-10 39.0 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO24450.1 - 1.8e-09 36.2 13.5 0.002 16.3 0.8 5.6 2 2 3 5 5 5 5 Nucleoporin Nup120/160 DUF3716 PF12511.3 ETO24451.1 - 0.21 11.2 5.1 0.046 13.3 1.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) MIP-T3 PF10243.4 ETO24451.1 - 4.3 5.6 31.9 0.043 12.3 16.7 1.5 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Frigida PF07899.6 ETO24452.1 - 0.11 11.2 4.9 0.16 10.6 3.4 1.2 1 0 0 1 1 1 0 Frigida-like protein RNA_pol_Rpb2_6 PF00562.23 ETO24453.1 - 0.094 11.4 2.0 0.14 10.8 1.4 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 DUF4286 PF14114.1 ETO24454.1 - 0.017 15.3 3.3 0.018 15.3 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4286) SPO22 PF08631.5 ETO24454.1 - 0.078 12.0 3.0 1.5 7.8 0.1 2.2 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like BcrAD_BadFG PF01869.15 ETO24455.1 - 0.073 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family ExbD PF02472.11 ETO24459.1 - 0.66 9.9 5.7 0.45 10.5 2.1 1.8 1 1 1 2 2 2 0 Biopolymer transport protein ExbD/TolR U-box PF04564.10 ETO24461.1 - 1e-12 47.8 0.3 5.6e-12 45.4 0.0 2.5 3 0 0 3 3 3 1 U-box domain VWA_2 PF13519.1 ETO24461.1 - 7.7e-08 32.6 0.0 3.9e-05 23.8 0.0 3.0 2 1 0 2 2 2 2 von Willebrand factor type A domain VWA PF00092.23 ETO24461.1 - 4e-07 29.9 0.0 4.7e-06 26.4 0.0 2.5 3 0 0 3 3 3 1 von Willebrand factor type A domain TEX19 PF15553.1 ETO24461.1 - 8.5 6.2 8.1 5.2 6.9 3.2 2.3 2 0 0 2 2 2 0 Testis-expressed protein 19 Kinesin PF00225.18 ETO24463.1 - 1.7e-59 201.2 1.6 1.7e-59 201.2 1.1 1.5 2 0 0 2 2 2 1 Kinesin motor domain Nodulin_late PF07127.6 ETO24463.1 - 1.5 9.0 8.6 2.9 8.0 0.2 3.5 3 0 0 3 3 3 0 Late nodulin protein Seryl_tRNA_N PF02403.17 ETO24463.1 - 6.5 6.8 12.0 1.4 8.9 5.5 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4131 PF13567.1 ETO24464.1 - 0.036 13.4 0.8 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF2956 PF11169.3 ETO24464.1 - 0.11 12.5 8.8 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Calcyon PF06387.6 ETO24464.1 - 0.11 11.8 2.5 0.14 11.5 1.1 1.6 2 0 0 2 2 2 0 D1 dopamine receptor-interacting protein (calcyon) VWA_2 PF13519.1 ETO24466.1 - 1.2e-23 84.1 0.0 1.8e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 ETO24466.1 - 7.6e-12 45.2 0.1 1.7e-11 44.1 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 ETO24466.1 - 1.1e-07 31.8 0.0 2.4e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_3 PF13768.1 ETO24466.1 - 4.9e-07 29.5 0.4 1.9e-06 27.6 0.3 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 ETO24466.1 - 0.0053 15.9 0.3 0.029 13.4 0.1 2.2 2 1 0 2 2 2 1 VWA domain containing CoxE-like protein DUF2201 PF09967.4 ETO24466.1 - 0.26 11.3 1.5 1.4 8.9 0.4 2.7 2 1 0 2 2 2 0 VWA-like domain (DUF2201) Kinesin PF00225.18 ETO24467.1 - 5.5e-09 35.1 0.5 6.8e-09 34.8 0.4 1.1 1 0 0 1 1 1 1 Kinesin motor domain FAM74 PF15026.1 ETO24468.1 - 0.097 12.3 2.4 0.18 11.4 1.6 1.5 1 0 0 1 1 1 0 FAM74 protein Bac_DnaA_C PF08299.6 ETO24470.1 - 0.1 12.4 0.1 7.5 6.4 0.0 2.3 1 1 1 2 2 2 0 Bacterial dnaA protein helix-turn-helix PAP2 PF01569.16 ETO24471.1 - 7.7e-16 57.9 5.1 7.7e-16 57.9 3.5 2.0 1 1 1 2 2 2 1 PAP2 superfamily Pox_Ag35 PF03286.9 ETO24471.1 - 0.0043 16.5 13.1 0.0043 16.5 9.1 2.4 2 0 0 2 2 2 1 Pox virus Ag35 surface protein DUF1184 PF06683.6 ETO24471.1 - 0.0081 15.8 1.5 0.022 14.3 1.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1184) DUF3487 PF11990.3 ETO24471.1 - 0.2 11.0 0.0 0.2 11.0 0.0 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF3487) HSP90 PF00183.13 ETO24473.1 - 0.33 9.2 8.4 0.51 8.6 5.8 1.3 1 0 0 1 1 1 0 Hsp90 protein Sin3_corepress PF08295.7 ETO24474.1 - 1.6e-11 43.8 0.2 3.2e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 Sin3 family co-repressor DUF1900 PF08954.6 ETO24477.1 - 7.7e-41 138.8 0.0 1.2e-40 138.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) IFP_35_N PF07334.8 ETO24477.1 - 0.011 15.6 3.1 0.056 13.4 0.1 2.4 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DivIC PF04977.10 ETO24477.1 - 0.022 14.2 0.9 0.046 13.2 0.6 1.5 1 0 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.10 ETO24477.1 - 0.23 11.3 2.0 0.39 10.5 1.4 1.3 1 0 0 1 1 1 0 Basic region leucine zipper RPEL PF02755.10 ETO24478.1 - 0.0007 18.8 5.9 0.22 10.9 0.0 3.7 3 0 0 3 3 3 2 RPEL repeat DnaI_N PF07319.6 ETO24478.1 - 0.04 14.1 1.2 0.04 14.1 0.8 2.4 2 1 1 3 3 3 0 Primosomal protein DnaI N-terminus ALMT PF11744.3 ETO24478.1 - 2.7 6.5 5.0 1.3 7.5 1.8 1.6 1 1 1 2 2 2 0 Aluminium activated malate transporter RPEL PF02755.10 ETO24479.1 - 9.9e-08 31.0 7.9 0.00059 19.0 0.1 3.6 3 0 0 3 3 3 2 RPEL repeat TPD52 PF04201.10 ETO24479.1 - 0.033 13.9 0.5 0.033 13.9 0.3 2.1 2 0 0 2 2 2 0 Tumour protein D52 family DUF1664 PF07889.7 ETO24479.1 - 0.69 9.7 4.5 19 5.0 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) HrpB7 PF09486.5 ETO24479.1 - 0.69 9.8 10.8 0.91 9.4 3.7 2.8 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) Peptidase_U57 PF05582.7 ETO24479.1 - 1 8.2 7.7 0.081 11.8 1.8 1.7 2 0 0 2 2 2 0 YabG peptidase U57 TMF_DNA_bd PF12329.3 ETO24479.1 - 2.5 7.9 16.4 0.036 13.8 2.5 2.8 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.6 ETO24479.1 - 2.8 7.8 6.2 28 4.7 0.0 3.8 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) zf-C4H2 PF10146.4 ETO24479.1 - 3.3 7.6 12.4 0.028 14.4 1.9 2.2 2 1 0 2 2 2 0 Zinc finger-containing protein TMF_TATA_bd PF12325.3 ETO24479.1 - 4.4 7.0 17.9 0.075 12.7 4.9 2.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF4140 PF13600.1 ETO24479.1 - 5.7 7.4 6.5 9.2 6.7 0.9 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) GAS PF13851.1 ETO24479.1 - 9.9 5.2 20.6 1.2 8.3 4.6 2.5 2 2 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF2457 PF10446.4 ETO24480.1 - 0.0058 15.4 1.4 0.0058 15.4 1.0 5.9 3 1 3 6 6 6 2 Protein of unknown function (DUF2457) AXE1 PF05448.7 ETO24481.1 - 0.083 11.3 0.1 0.16 10.4 0.0 1.5 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) SDA1 PF05285.7 ETO24481.1 - 0.17 11.1 23.9 0.23 10.7 16.6 1.3 1 0 0 1 1 1 0 SDA1 REJ PF02010.10 ETO24483.1 - 0.0059 14.9 0.1 0.0082 14.5 0.1 1.4 1 1 0 1 1 1 1 REJ domain Aminoglyc_resit PF10706.4 ETO24483.1 - 0.1 12.1 0.5 0.19 11.3 0.4 1.3 1 0 0 1 1 1 0 Aminoglycoside-2''-adenylyltransferase Cyclin_C PF02984.14 ETO24484.1 - 0.035 14.0 0.1 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Cyclin, C-terminal domain Sulfotransfer_2 PF03567.9 ETO24485.1 - 4.4e-10 39.6 4.0 4.4e-10 39.6 2.8 2.0 2 1 0 2 2 2 1 Sulfotransferase family Alpha_L_fucos PF01120.12 ETO24485.1 - 0.0066 15.3 0.9 0.0099 14.8 0.6 1.2 1 0 0 1 1 1 1 Alpha-L-fucosidase YppF PF14178.1 ETO24485.1 - 0.081 12.4 0.0 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 YppF-like protein Peptidase_M24 PF00557.19 ETO24486.1 - 2.4e-06 27.3 0.2 3e-06 26.9 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Miff PF05644.6 ETO24488.1 - 0.00056 19.6 0.8 0.00066 19.3 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial and peroxisomal fission factor Mff Nop14 PF04147.7 ETO24488.1 - 0.023 12.6 5.3 0.027 12.3 3.7 1.1 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.2 ETO24488.1 - 0.22 9.1 5.0 0.21 9.2 3.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2201_N PF13203.1 ETO24488.1 - 1 8.4 6.1 1.3 8.1 4.2 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Daxx PF03344.10 ETO24488.1 - 1 7.7 9.7 1.1 7.6 6.7 1.0 1 0 0 1 1 1 0 Daxx Family FAM176 PF14851.1 ETO24488.1 - 1.7 8.3 6.1 2.2 7.9 4.2 1.1 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.9 ETO24488.1 - 1.7 6.5 8.2 1.9 6.4 5.7 1.0 1 0 0 1 1 1 0 CDC45-like protein HNOBA PF07701.9 ETO24488.1 - 6.2 5.9 6.2 1.4 8.0 0.0 2.1 2 0 0 2 2 2 0 Heme NO binding associated MFS_1 PF07690.11 ETO24489.1 - 1.8e-09 36.7 10.5 2.9e-09 36.1 7.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily FAM176 PF14851.1 ETO24489.1 - 0.019 14.6 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 FAM176 family Bax1-I PF01027.15 ETO24489.1 - 2.8 7.5 20.4 0.14 11.6 10.2 1.7 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 Peptidase_M22 PF00814.20 ETO24491.1 - 0.032 13.7 0.0 0.39 10.1 0.0 2.1 2 0 0 2 2 2 0 Glycoprotease family Myb_Cef PF11831.3 ETO24492.1 - 6.7e-26 90.9 15.3 1.3e-25 90.0 10.6 1.4 1 0 0 1 1 1 1 pre-mRNA splicing factor component DUF4474 PF14751.1 ETO24492.1 - 0.018 14.2 0.6 0.035 13.2 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4474) RdRP PF05183.7 ETO24493.1 - 2.2e-25 89.4 0.5 8.5e-25 87.4 0.1 1.9 1 1 1 2 2 2 1 RNA dependent RNA polymerase RRM_6 PF14259.1 ETO24493.1 - 0.0018 18.2 0.1 0.01 15.8 0.0 2.4 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO24493.1 - 0.012 15.2 0.0 0.031 13.8 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MutL_C PF08676.6 ETO24493.1 - 0.091 12.3 0.0 0.24 11.0 0.0 1.6 2 0 0 2 2 2 0 MutL C terminal dimerisation domain RdRP PF05183.7 ETO24494.1 - 2.9e-62 211.2 0.1 3.4e-62 210.9 0.0 1.0 1 0 0 1 1 1 1 RNA dependent RNA polymerase RdRP PF05183.7 ETO24495.1 - 1.3e-11 43.9 0.1 3.4e-11 42.5 0.0 1.6 2 0 0 2 2 2 1 RNA dependent RNA polymerase DUF3135 PF11333.3 ETO24495.1 - 0.018 15.2 0.8 0.12 12.6 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3135) SBDS_C PF09377.5 ETO24495.1 - 0.054 13.1 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 SBDS protein C-terminal domain HPS3_Mid PF14762.1 ETO24495.1 - 0.079 11.5 0.1 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3, middle region WD40 PF00400.27 ETO24496.1 - 2.2e-80 261.9 20.0 3e-12 45.8 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO24496.1 - 7e-07 27.8 1.3 0.0073 14.6 0.1 2.8 2 1 0 3 3 3 2 Cytochrome D1 heme domain PD40 PF07676.7 ETO24496.1 - 7.3e-05 22.3 10.8 1.5 8.6 0.0 6.3 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO24496.1 - 0.0059 16.8 0.0 1.5e+02 2.7 0.0 4.9 2 1 3 5 5 5 0 Resistin Nbas_N PF15492.1 ETO24496.1 - 0.0086 15.2 1.7 0.34 9.9 0.0 3.3 1 1 3 5 5 5 1 Neuroblastoma-amplified sequence, N terminal SGL PF08450.7 ETO24496.1 - 0.016 14.5 0.1 0.52 9.6 0.0 2.6 1 1 1 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region Gmad1 PF10647.4 ETO24496.1 - 0.018 14.4 0.1 1.3 8.4 0.0 2.7 1 1 2 3 3 3 0 Lipoprotein LpqB beta-propeller domain Proteasome_A_N PF10584.4 ETO24496.1 - 4.9 6.5 0.0 4.9 6.5 0.0 5.0 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature NUC130_3NT PF08158.7 ETO24497.1 - 0.052 13.8 0.0 5.3 7.4 0.0 2.4 2 0 0 2 2 2 0 NUC130/3NT domain Pkinase PF00069.20 ETO24498.1 - 3.7e-17 62.3 0.0 1.8e-14 53.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO24498.1 - 0.002 17.2 0.1 0.86 8.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Sporozoite_P67 PF05642.6 ETO24498.1 - 0.03 12.2 9.5 0.039 11.8 6.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.9 ETO24498.1 - 0.069 11.1 16.9 0.097 10.6 11.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 ETO24498.1 - 0.25 10.7 17.0 0.34 10.2 11.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Hid1 PF12722.2 ETO24498.1 - 0.46 8.1 3.8 0.57 7.8 2.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Daxx PF03344.10 ETO24498.1 - 1.7 7.0 17.7 2 6.8 12.3 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 ETO24498.1 - 2 6.2 21.7 2.7 5.8 15.1 1.1 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.13 ETO24498.1 - 2.2 7.3 10.7 3.5 6.7 7.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region PA28_beta PF02252.13 ETO24500.1 - 2e-20 72.8 0.9 3.4e-20 72.0 0.0 1.8 2 0 0 2 2 2 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.13 ETO24500.1 - 0.0015 18.6 2.9 0.0015 18.6 2.0 2.3 2 0 0 2 2 2 1 Proteasome activator pa28 alpha subunit Ribosomal_L17 PF01196.14 ETO24500.1 - 0.032 14.7 1.1 0.38 11.3 0.6 2.5 2 0 0 2 2 2 0 Ribosomal protein L17 GlutR_dimer PF00745.15 ETO24500.1 - 0.63 10.0 4.4 1.4 8.8 0.1 2.4 1 1 1 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain PMM PF03332.8 ETO24501.1 - 5.4e-85 284.4 2.5 6.6e-85 284.1 1.8 1.1 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 ETO24501.1 - 7.7e-05 22.3 0.0 0.00046 19.8 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 ETO24501.1 - 0.055 12.7 0.0 5.7 6.1 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Vps35 PF03635.12 ETO24502.1 - 3.8e-38 131.1 0.1 4.3e-38 131.0 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 IBR PF01485.16 ETO24503.1 - 3.4e-11 42.8 39.5 2.6e-07 30.3 7.7 4.3 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 ETO24503.1 - 0.00019 21.2 9.9 0.00019 21.2 6.9 3.6 2 1 1 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.1 ETO24503.1 - 0.00033 20.6 13.3 0.00033 20.6 9.2 4.3 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO24503.1 - 0.0056 16.3 10.1 0.0056 16.3 7.0 5.0 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Peptidase_C23 PF05379.6 ETO24504.1 - 0.024 14.5 0.1 0.087 12.8 0.0 1.9 2 0 0 2 2 2 0 Carlavirus endopeptidase Ependymin PF00811.13 ETO24504.1 - 0.026 14.2 0.8 0.071 12.8 0.6 1.8 1 0 0 1 1 1 0 Ependymin zf-C3HC4_2 PF13923.1 ETO24505.1 - 0.00027 20.8 2.3 0.00099 19.0 1.6 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO24505.1 - 0.00027 20.6 4.9 0.00061 19.5 3.4 1.6 1 0 0 1 1 1 1 Ring finger domain Tet_JBP PF12851.2 ETO24505.1 - 0.029 13.6 2.1 0.033 13.5 1.5 1.2 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily OAF PF14941.1 ETO24506.1 - 0.0095 15.1 0.5 0.014 14.5 0.3 1.2 1 0 0 1 1 1 1 Transcriptional regulator, Out at first TFIIS_M PF07500.9 ETO24506.1 - 0.088 12.8 1.3 0.11 12.5 0.3 1.7 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS), central domain WBP-1 PF11669.3 ETO24507.1 - 2.6 8.1 6.3 6 6.9 4.4 1.6 1 0 0 1 1 1 0 WW domain-binding protein 1 SIR2 PF02146.12 ETO24509.1 - 0.024 14.3 0.1 0.034 13.8 0.0 1.1 1 0 0 1 1 1 0 Sir2 family FerB PF08150.7 ETO24509.1 - 0.091 12.8 0.0 0.26 11.3 0.0 1.7 2 0 0 2 2 2 0 FerB (NUC096) domain BcrAD_BadFG PF01869.15 ETO24509.1 - 0.12 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family ETRAMP PF09716.5 ETO24510.1 - 5.2 7.0 9.6 0.63 10.0 0.3 2.6 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) HSP70 PF00012.15 ETO24511.1 - 5.8e-15 54.2 1.3 5.8e-15 54.2 0.9 4.0 2 2 2 4 4 4 1 Hsp70 protein MMR_HSR1 PF01926.18 ETO24511.1 - 3.7e-06 26.8 0.0 1.8e-05 24.6 0.0 2.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 ETO24511.1 - 0.0041 17.2 0.0 0.04 14.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ETO24511.1 - 0.019 15.7 3.8 0.31 11.8 0.0 3.6 4 0 0 4 4 4 0 AAA domain AAA_16 PF13191.1 ETO24511.1 - 0.041 13.8 0.9 0.22 11.4 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 ETO24511.1 - 0.042 13.3 0.0 0.13 11.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 ETO24511.1 - 0.1 12.8 0.0 0.1 12.8 0.0 3.4 4 0 0 4 4 4 0 ABC transporter Secretin_N_2 PF07655.8 ETO24511.1 - 2.6 8.4 9.6 13 6.2 2.9 3.0 2 0 0 2 2 2 0 Secretin N-terminal domain SopA PF13981.1 ETO24513.1 - 0.051 13.5 0.2 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 SopA-like central domain Vma12 PF11712.3 ETO24514.1 - 0.01 15.5 0.1 0.01 15.5 0.1 2.3 2 0 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Mem_trans PF03547.13 ETO24514.1 - 0.24 9.6 2.1 0.37 9.0 0.2 2.0 2 0 0 2 2 2 0 Membrane transport protein DUF106 PF01956.11 ETO24514.1 - 0.44 10.0 3.6 5.6 6.4 0.6 3.0 3 0 0 3 3 3 0 Integral membrane protein DUF106 EIIBC-GUT_N PF03612.9 ETO24514.1 - 5.2 6.6 9.1 0.59 9.7 0.7 2.6 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus C2 PF00168.25 ETO24515.1 - 2e-07 30.7 0.2 1.1e-06 28.4 0.0 2.1 1 1 1 2 2 2 1 C2 domain HEAT PF02985.17 ETO24516.1 - 0.027 14.5 0.0 31 5.0 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat TMEM213 PF15192.1 ETO24516.1 - 0.039 13.9 0.1 0.093 12.7 0.1 1.6 1 0 0 1 1 1 0 TMEM213 family Arm PF00514.18 ETO24516.1 - 0.048 13.5 0.5 53 3.8 0.0 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 ETO24516.1 - 0.049 14.1 0.1 1.4e+02 3.1 0.0 4.7 4 2 1 5 5 5 0 HEAT-like repeat CDC45 PF02724.9 ETO24518.1 - 0.00056 18.0 13.4 0.00057 18.0 9.3 1.1 1 0 0 1 1 1 1 CDC45-like protein RPEL PF02755.10 ETO24518.1 - 0.0023 17.1 0.0 0.0023 17.1 0.0 2.5 2 1 0 2 2 1 1 RPEL repeat Nop53 PF07767.6 ETO24518.1 - 0.0057 15.7 20.5 0.006 15.6 14.2 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Daxx PF03344.10 ETO24518.1 - 0.0066 15.0 16.1 0.0075 14.8 11.2 1.1 1 0 0 1 1 1 1 Daxx Family Merozoite_SPAM PF07133.6 ETO24518.1 - 0.012 15.5 21.4 0.014 15.3 14.8 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Drc1-Sld2 PF11719.3 ETO24518.1 - 0.013 14.6 13.9 0.013 14.5 9.7 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein RRN3 PF05327.6 ETO24518.1 - 0.037 12.1 10.8 0.039 12.0 7.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HSP90 PF00183.13 ETO24518.1 - 0.065 11.6 23.0 0.094 11.0 15.9 1.2 1 0 0 1 1 1 0 Hsp90 protein DDHD PF02862.12 ETO24518.1 - 0.072 12.8 9.3 0.081 12.7 6.4 1.2 1 0 0 1 1 1 0 DDHD domain YqfQ PF14181.1 ETO24518.1 - 0.2 11.6 16.1 0.31 11.0 11.2 1.3 1 0 0 1 1 1 0 YqfQ-like protein DUF2722 PF10846.3 ETO24518.1 - 0.25 10.3 10.5 0.32 9.9 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Paf1 PF03985.8 ETO24518.1 - 0.28 9.8 22.2 0.36 9.5 15.4 1.1 1 0 0 1 1 1 0 Paf1 Ycf1 PF05758.7 ETO24518.1 - 0.3 8.7 15.2 0.31 8.7 10.5 1.0 1 0 0 1 1 1 0 Ycf1 TFIIF_alpha PF05793.7 ETO24518.1 - 0.34 9.2 27.3 0.43 8.8 18.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RR_TM4-6 PF06459.7 ETO24518.1 - 0.35 10.7 13.2 0.45 10.3 9.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Herpes_DNAp_acc PF04929.7 ETO24518.1 - 0.44 9.4 9.9 0.58 9.0 6.8 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor GAGA_bind PF06217.7 ETO24518.1 - 0.46 10.4 9.6 0.45 10.4 6.7 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family CobT PF06213.7 ETO24518.1 - 0.49 9.4 16.5 0.29 10.2 10.4 1.4 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Astro_capsid PF03115.9 ETO24518.1 - 0.7 8.0 5.7 0.69 8.0 4.0 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF3381 PF11861.3 ETO24518.1 - 0.75 9.2 26.1 1.5 8.3 18.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Peptidase_U57 PF05582.7 ETO24518.1 - 1.3 7.9 10.4 9.1 5.1 5.1 2.0 2 0 0 2 2 2 0 YabG peptidase U57 SID-1_RNA_chan PF13965.1 ETO24518.1 - 1.5 6.9 4.7 1.5 6.8 3.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Prog_receptor PF02161.10 ETO24518.1 - 1.5 7.5 7.2 1.7 7.3 5.0 1.1 1 0 0 1 1 1 0 Progesterone receptor PLRV_ORF5 PF01690.12 ETO24518.1 - 1.6 7.7 10.5 1.6 7.7 7.3 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein PMSI1 PF15322.1 ETO24518.1 - 1.8 7.6 6.1 2.2 7.3 4.2 1.3 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative DUF1510 PF07423.6 ETO24518.1 - 1.9 7.7 20.3 2.7 7.3 14.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RNA_pol_Rpb1_5 PF04998.12 ETO24518.1 - 3.1 6.9 6.2 3.6 6.7 4.3 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 TRAP_alpha PF03896.11 ETO24518.1 - 3.6 6.5 11.4 5.4 5.9 7.9 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Mem_trans PF03547.13 ETO24518.1 - 3.7 5.7 4.5 4.1 5.5 3.1 1.1 1 0 0 1 1 1 0 Membrane transport protein Zip PF02535.17 ETO24518.1 - 4.6 6.1 5.8 5.3 5.9 4.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter IncFII_repA PF02387.10 ETO24518.1 - 4.8 6.2 12.2 5.2 6.1 8.4 1.1 1 0 0 1 1 1 0 IncFII RepA protein family Neur_chan_memb PF02932.11 ETO24518.1 - 5.9 6.6 7.4 7.3 6.4 5.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CAF-1_p150 PF11600.3 ETO24518.1 - 7.9 5.7 35.0 11 5.3 24.3 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal MIP-T3 PF10243.4 ETO24520.1 - 0.3 9.5 25.6 0.38 9.1 17.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Zip PF02535.17 ETO24520.1 - 0.34 9.8 5.7 0.5 9.3 3.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1510 PF07423.6 ETO24520.1 - 1.5 8.1 21.6 2.4 7.4 15.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Peroxin-3 PF04882.7 ETO24520.1 - 1.6 7.3 10.4 2.8 6.5 7.2 1.2 1 0 0 1 1 1 0 Peroxin-3 CobT PF06213.7 ETO24520.1 - 2.2 7.3 16.6 2.1 7.4 9.5 2.0 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DDHD PF02862.12 ETO24520.1 - 2.2 7.9 10.2 3.7 7.2 7.0 1.3 1 0 0 1 1 1 0 DDHD domain RNase_H2-Ydr279 PF09468.5 ETO24520.1 - 4.3 6.4 15.4 6.8 5.7 10.6 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) RR_TM4-6 PF06459.7 ETO24520.1 - 6.7 6.5 14.0 11 5.8 9.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RasGEF PF00617.14 ETO24521.1 - 6.2e-11 42.3 7.2 7.2e-11 42.1 1.9 2.6 2 0 0 2 2 2 1 RasGEF domain Pantoate_transf PF02548.10 ETO24523.1 - 0.12 11.5 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase PI3_PI4_kinase PF00454.22 ETO24525.1 - 3.8e-47 160.7 0.1 7e-47 159.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 ETO24525.1 - 6e-13 47.9 0.6 2e-12 46.2 0.4 1.9 1 0 0 1 1 1 1 FATC domain FA_desaturase PF00487.19 ETO24527.1 - 1.4 8.3 12.2 0.21 11.0 5.8 1.6 1 1 1 2 2 2 0 Fatty acid desaturase TRAPPC-Trs85 PF12739.2 ETO24529.1 - 0.31 9.6 6.5 0.44 9.1 4.5 1.2 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DUF2217 PF10265.4 ETO24529.1 - 0.51 9.0 4.3 0.54 8.9 3.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Pkinase PF00069.20 ETO24530.1 - 1.1e-63 214.7 0.0 1.6e-63 214.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO24530.1 - 7.3e-27 94.0 0.0 1.2e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO24530.1 - 1.5e-06 27.4 0.1 0.00035 19.6 0.0 2.4 1 1 0 2 2 2 2 Kinase-like cNMP_binding PF00027.24 ETO24530.1 - 0.0011 18.7 1.4 0.65 9.8 0.1 3.2 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain AAA_14 PF13173.1 ETO24530.1 - 0.035 14.0 0.6 0.092 12.6 0.4 1.7 1 0 0 1 1 1 0 AAA domain FimP PF09766.4 ETO24530.1 - 1.5 7.7 10.3 0.24 10.3 4.4 1.6 2 0 0 2 2 2 0 Fms-interacting protein UNC-50 PF05216.8 ETO24531.1 - 4e-20 72.0 13.6 4e-20 72.0 9.4 1.5 1 1 1 2 2 2 1 UNC-50 family Glyco_hydro_76 PF03663.9 ETO24533.1 - 1.1e-20 74.4 6.1 1.2e-20 74.2 4.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 RasGEF_N PF00618.15 ETO24534.1 - 0.9 9.6 13.7 3.4 7.8 9.4 2.1 1 1 0 1 1 1 0 RasGEF N-terminal motif S-antigen PF05756.6 ETO24534.1 - 7 6.7 14.2 0.21 11.6 4.0 2.5 2 0 0 2 2 2 0 S-antigen protein HALZ PF02183.13 ETO24541.1 - 0.047 13.4 6.2 0.23 11.2 0.7 3.2 1 1 1 2 2 2 0 Homeobox associated leucine zipper Peptidase_S46 PF10459.4 ETO24541.1 - 0.4 9.0 13.0 0.69 8.2 9.0 1.4 1 0 0 1 1 1 0 Peptidase S46 bZIP_1 PF00170.16 ETO24541.1 - 4.8 7.2 18.8 0.4 10.6 2.2 4.2 2 2 3 5 5 5 0 bZIP transcription factor Rootletin PF15035.1 ETO24541.1 - 7.1 6.5 22.4 1.2 9.1 6.6 3.4 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Prefoldin_3 PF13758.1 ETO24541.1 - 8.8 6.1 10.8 5 6.9 1.7 2.9 1 1 1 2 2 2 0 Prefoldin subunit IncA PF04156.9 ETO24542.1 - 0.036 13.6 3.1 0.046 13.3 2.1 1.3 1 0 0 1 1 1 0 IncA protein ATP-synt_E PF05680.7 ETO24542.1 - 2.9 7.9 5.2 6.6 6.7 3.6 1.6 1 0 0 1 1 1 0 ATP synthase E chain DUF4163 PF13739.1 ETO24542.1 - 5.6 7.8 6.1 2 9.2 1.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4163) Peptidase_S10 PF00450.17 ETO24544.1 - 9.9e-18 64.4 0.0 1.4e-12 47.5 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase ubiquitin PF00240.18 ETO24545.1 - 4.4e-08 32.3 0.0 8.6e-08 31.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family 2OG-FeII_Oxy PF03171.15 ETO24545.1 - 0.038 14.2 0.0 0.087 13.1 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily YxiJ PF14176.1 ETO24546.1 - 0.0031 17.5 2.7 0.0031 17.5 1.9 1.3 1 1 0 1 1 1 1 YxiJ-like protein Filament PF00038.16 ETO24546.1 - 0.0058 16.1 6.7 0.0073 15.8 4.6 1.1 1 0 0 1 1 1 1 Intermediate filament protein BLOC1_2 PF10046.4 ETO24546.1 - 0.007 16.4 0.9 0.007 16.4 0.7 2.5 1 1 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.6 ETO24546.1 - 0.01 15.6 1.3 0.023 14.5 0.3 2.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Laminin_I PF06008.9 ETO24546.1 - 0.017 14.4 6.4 0.012 14.8 1.3 1.9 1 1 1 2 2 2 0 Laminin Domain I NYD-SP28 PF14772.1 ETO24546.1 - 0.019 15.0 2.2 0.019 15.0 1.5 2.0 1 1 1 2 2 2 0 Sperm tail PurA PF04845.8 ETO24546.1 - 0.027 13.5 0.5 0.03 13.4 0.4 1.2 1 0 0 1 1 1 0 PurA ssDNA and RNA-binding protein Interferon PF00143.14 ETO24546.1 - 0.036 13.9 1.0 0.063 13.1 0.6 1.5 1 1 0 1 1 1 0 Interferon alpha/beta domain DUF3452 PF11934.3 ETO24546.1 - 0.04 13.2 2.4 0.087 12.1 1.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) Cob_adeno_trans PF01923.13 ETO24546.1 - 0.057 13.1 1.2 0.073 12.8 0.9 1.3 1 0 0 1 1 1 0 Cobalamin adenosyltransferase LUC7 PF03194.10 ETO24546.1 - 0.063 12.8 4.6 0.15 11.6 3.0 1.6 1 1 0 1 1 1 0 LUC7 N_terminus YqaJ PF09588.5 ETO24546.1 - 0.077 12.9 0.1 0.092 12.7 0.0 1.3 1 0 0 1 1 1 0 YqaJ-like viral recombinase domain GAS PF13851.1 ETO24546.1 - 0.086 12.0 8.4 0.11 11.7 5.8 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding FCH PF00611.18 ETO24546.1 - 0.093 12.9 3.0 0.17 12.0 1.3 1.9 1 1 1 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain ApoLp-III PF07464.6 ETO24546.1 - 0.094 12.7 8.1 0.15 12.1 1.4 2.1 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) CAMSAP_CH PF11971.3 ETO24546.1 - 0.11 12.1 0.5 0.24 11.0 0.1 1.7 1 1 1 2 2 2 0 CAMSAP CH domain TIP120 PF08623.5 ETO24546.1 - 0.11 12.0 2.9 0.15 11.6 1.5 1.4 1 1 0 1 1 1 0 TATA-binding protein interacting (TIP20) MitMem_reg PF13012.1 ETO24546.1 - 0.12 12.4 6.0 0.24 11.4 0.2 2.2 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function IncA PF04156.9 ETO24546.1 - 0.13 11.8 10.8 0.095 12.2 4.8 1.9 1 1 1 2 2 2 0 IncA protein Big_5 PF13205.1 ETO24546.1 - 0.13 12.8 0.0 0.17 12.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial Ig-like domain Tweety PF04906.8 ETO24546.1 - 0.15 10.4 2.2 0.19 10.1 1.3 1.2 1 1 0 1 1 1 0 Tweety Cep57_CLD_2 PF14197.1 ETO24546.1 - 0.18 11.7 3.7 0.17 11.8 0.9 2.1 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 zf-C4H2 PF10146.4 ETO24546.1 - 0.19 11.7 3.7 0.21 11.6 2.6 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein DASH_Dad1 PF08649.5 ETO24546.1 - 0.2 11.3 2.9 0.17 11.6 0.3 2.2 2 1 0 2 2 2 0 DASH complex subunit Dad1 Prefoldin_2 PF01920.15 ETO24546.1 - 0.69 9.6 9.7 1 9.1 0.5 2.9 2 1 1 3 3 3 0 Prefoldin subunit YlqD PF11068.3 ETO24546.1 - 0.72 9.8 8.0 0.21 11.6 3.1 1.7 1 1 1 2 2 2 0 YlqD protein Baculo_PEP_C PF04513.7 ETO24546.1 - 0.85 9.4 5.3 2.1 8.1 1.4 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.5 ETO24546.1 - 0.9 9.6 8.6 0.99 9.5 3.9 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.7 ETO24546.1 - 1.9 8.2 7.3 0.87 9.3 2.8 1.9 1 1 1 2 2 2 0 Laminin Domain II Epsilon_antitox PF08998.6 ETO24546.1 - 2.4 8.2 9.5 2.6 8.0 0.2 2.5 1 1 1 2 2 2 0 Bacterial epsilon antitoxin TMPIT PF07851.8 ETO24546.1 - 2.6 7.0 6.9 3.3 6.6 4.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein DMPK_coil PF08826.5 ETO24546.1 - 2.9 7.8 6.0 0.86 9.5 1.1 2.2 2 2 0 2 2 2 0 DMPK coiled coil domain like HR1 PF02185.11 ETO24546.1 - 3.7 7.3 7.5 3.6 7.3 0.1 2.4 2 0 0 2 2 2 0 Hr1 repeat TP6A_N PF04406.9 ETO24547.1 - 0.097 12.3 0.3 0.18 11.4 0.2 1.4 1 0 0 1 1 1 0 Type IIB DNA topoisomerase Antifungal_prot PF11402.3 ETO24547.1 - 2.7 8.2 12.0 0.29 11.3 4.4 2.2 2 1 0 2 2 2 0 Antifungal protein THOC7 PF05615.8 ETO24548.1 - 0.0026 18.0 5.9 0.0026 18.0 4.1 2.0 2 1 0 2 2 2 1 Tho complex subunit 7 TPR_MLP1_2 PF07926.7 ETO24548.1 - 0.016 14.9 6.6 0.016 14.9 4.6 2.7 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Pirin_C PF05726.8 ETO24548.1 - 0.021 14.8 0.5 0.063 13.3 0.0 2.0 2 0 0 2 2 2 0 Pirin C-terminal cupin domain TPR_12 PF13424.1 ETO24549.1 - 2e-54 181.4 19.3 2e-19 69.2 1.0 4.8 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.23 ETO24549.1 - 3.5e-32 108.6 28.9 1.3e-08 34.1 0.4 7.0 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.1 ETO24549.1 - 7e-30 102.4 14.3 3.4e-11 42.6 0.2 4.7 3 1 1 4 4 4 4 TPR repeat TPR_10 PF13374.1 ETO24549.1 - 2.7e-25 87.5 0.0 2.6e-05 23.9 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO24549.1 - 6.4e-25 85.0 20.1 1.9e-06 27.3 0.2 6.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.1 ETO24549.1 - 5.4e-20 69.5 12.8 0.00023 20.7 0.1 6.8 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO24549.1 - 1.2e-14 52.9 32.5 0.00019 20.9 1.3 6.9 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 ETO24549.1 - 1.4e-11 44.7 0.0 0.029 15.0 0.1 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat MIT PF04212.13 ETO24549.1 - 4.1e-10 39.3 17.7 0.02 14.7 0.1 6.3 4 2 2 6 6 5 3 MIT (microtubule interacting and transport) domain DUF2225 PF09986.4 ETO24549.1 - 1.5e-08 34.3 14.0 4e-05 23.1 2.5 3.5 2 1 1 3 3 3 3 Uncharacterized protein conserved in bacteria (DUF2225) TPR_6 PF13174.1 ETO24549.1 - 1e-07 31.8 12.9 0.16 12.4 0.2 6.6 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO24549.1 - 3.1e-06 27.3 0.0 0.45 11.2 0.0 5.5 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO24549.1 - 1.5e-05 24.8 11.4 0.61 10.4 0.6 5.4 3 2 1 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO24549.1 - 3.7e-05 23.7 18.2 0.055 13.6 2.1 4.1 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 ETO24549.1 - 0.00038 19.6 0.3 1 8.6 0.0 3.8 3 0 0 3 3 3 1 SHNi-TPR TPR_19 PF14559.1 ETO24549.1 - 0.0016 18.7 0.1 3.5 8.0 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Prefoldin PF02996.12 ETO24549.1 - 0.019 14.6 6.5 0.064 12.9 0.5 3.8 3 1 0 3 3 3 0 Prefoldin subunit PB1 PF00564.19 ETO24549.1 - 0.028 14.0 0.0 0.37 10.4 0.0 2.8 3 0 0 3 3 3 0 PB1 domain PPR PF01535.15 ETO24549.1 - 0.045 13.7 0.5 10 6.3 0.1 4.3 4 0 0 4 4 3 0 PPR repeat TPR_3 PF07720.7 ETO24549.1 - 0.069 12.9 20.1 0.06 13.1 2.2 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF627 PF04781.7 ETO24549.1 - 0.085 12.4 9.1 1.4 8.5 0.4 4.1 4 1 0 4 4 4 0 Protein of unknown function (DUF627) Mob_Pre PF01076.14 ETO24549.1 - 0.54 9.8 7.8 0.037 13.6 0.9 2.4 3 0 0 3 3 3 0 Plasmid recombination enzyme RLAN PF14401.1 ETO24549.1 - 0.8 9.2 7.7 0.65 9.4 0.3 3.6 5 0 0 5 5 5 0 RimK-like ATPgrasp N-terminal domain Sel1 PF08238.7 ETO24549.1 - 1.3 9.8 12.9 82 4.0 0.2 5.5 5 0 0 5 5 5 0 Sel1 repeat WD40 PF00400.27 ETO24550.1 - 3.4e-162 521.2 54.0 5.7e-13 48.2 0.3 16.5 16 0 0 16 16 16 16 WD domain, G-beta repeat Nup160 PF11715.3 ETO24550.1 - 6.4e-13 47.6 24.9 0.28 9.2 0.1 11.6 2 2 10 13 13 13 8 Nucleoporin Nup120/160 NACHT PF05729.7 ETO24550.1 - 6.4e-11 42.1 0.0 1.3e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Str_synth PF03088.11 ETO24550.1 - 3e-09 36.8 3.6 1 9.4 0.0 8.7 8 3 3 11 11 10 2 Strictosidine synthase Pentapeptide PF00805.17 ETO24550.1 - 1.4e-05 24.1 0.3 3.3e-05 22.9 0.2 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) AAA_22 PF13401.1 ETO24550.1 - 0.00011 22.2 0.0 0.00036 20.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain Pentapeptide_4 PF13599.1 ETO24550.1 - 0.00039 20.1 0.1 0.0011 18.6 0.1 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA_18 PF13238.1 ETO24550.1 - 0.00051 20.3 0.1 0.00051 20.3 0.1 4.5 5 2 0 5 5 4 1 AAA domain Pentapeptide_3 PF13576.1 ETO24550.1 - 0.00087 19.1 0.2 0.0021 17.9 0.1 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) PD40 PF07676.7 ETO24550.1 - 0.0028 17.2 20.4 6.8 6.4 0.0 8.1 9 0 0 9 9 9 1 WD40-like Beta Propeller Repeat AAA PF00004.24 ETO24550.1 - 0.0066 16.6 0.1 0.069 13.3 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 ETO24550.1 - 0.013 16.2 0.1 0.12 13.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain Mst1_SARAH PF11629.3 ETO24550.1 - 0.031 14.0 1.9 0.15 11.9 0.2 3.0 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 AAA_16 PF13191.1 ETO24550.1 - 0.063 13.2 0.1 0.7 9.8 0.0 2.6 1 1 0 1 1 1 0 AAA ATPase domain Arf PF00025.16 ETO24551.1 - 1e-10 41.1 2.3 1e-07 31.3 0.1 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family TRAP_alpha PF03896.11 ETO24551.1 - 0.026 13.5 0.1 0.026 13.5 0.1 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Ribosomal_60s PF00428.14 ETO24551.1 - 4.3 7.8 9.9 0.61 10.5 2.3 2.4 2 1 0 2 2 2 0 60s Acidic ribosomal protein PseudoU_synth_1 PF01416.15 ETO24557.1 - 0.0027 18.1 0.4 0.0066 16.8 0.3 1.7 1 0 0 1 1 1 1 tRNA pseudouridine synthase Shikimate_DH PF01488.15 ETO24557.1 - 0.037 14.1 0.8 0.27 11.3 0.5 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Nup88 PF10168.4 ETO24557.1 - 0.12 10.2 10.6 0.15 9.8 7.3 1.2 1 0 0 1 1 1 0 Nuclear pore component DUF3391 PF11871.3 ETO24557.1 - 0.52 10.5 9.0 1.1 9.4 0.7 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) DUF3086 PF11285.3 ETO24557.1 - 1.1 8.0 8.2 0.89 8.3 4.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3086) DUF3186 PF11382.3 ETO24557.1 - 1.9 7.5 5.6 0.69 8.9 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3186) DEAD PF00270.24 ETO24559.1 - 1.7e-08 34.1 0.0 2.6e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_25 PF13481.1 ETO24559.1 - 0.032 13.6 0.0 0.07 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 ETO24559.1 - 0.062 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain PhoH PF02562.11 ETO24559.1 - 0.11 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein Topoisom_I_N PF02919.10 ETO24561.1 - 0.06 12.6 3.8 0.13 11.5 2.7 1.6 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment MRG PF05712.8 ETO24562.1 - 9.8e-05 21.3 1.7 0.00022 20.2 1.2 1.7 1 1 0 1 1 1 1 MRG HEAT_2 PF13646.1 ETO24563.1 - 0.043 14.1 0.1 0.2 11.9 0.1 2.1 2 0 0 2 2 2 0 HEAT repeats Speriolin_N PF15058.1 ETO24565.1 - 0.0011 18.9 2.4 0.0015 18.4 1.7 1.4 1 0 0 1 1 1 1 Speriolin N terminus HALZ PF02183.13 ETO24565.1 - 0.0076 15.9 5.0 0.0076 15.9 3.5 3.3 2 1 1 3 3 3 1 Homeobox associated leucine zipper ERM PF00769.14 ETO24565.1 - 0.021 14.3 18.7 0.029 13.9 13.0 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DivIC PF04977.10 ETO24565.1 - 0.022 14.2 8.4 0.022 14.2 5.8 2.6 3 1 0 3 3 3 0 Septum formation initiator Kinesin-relat_1 PF12711.2 ETO24565.1 - 0.18 12.1 14.0 0.35 11.3 7.1 2.4 2 0 0 2 2 2 0 Kinesin motor V_ATPase_I PF01496.14 ETO24565.1 - 0.5 8.1 10.8 0.53 8.0 7.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_1 PF00170.16 ETO24565.1 - 0.64 10.0 14.0 0.31 11.0 6.6 2.6 2 1 0 2 2 2 0 bZIP transcription factor DUF4140 PF13600.1 ETO24565.1 - 8.9 6.8 8.6 9.1 6.7 3.5 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) APG9 PF04109.11 ETO24567.1 - 8.3e-70 235.5 11.6 2.6e-27 95.7 0.2 4.1 4 0 0 4 4 4 4 Autophagy protein Apg9 DEP PF00610.16 ETO24568.1 - 0.0041 16.8 0.1 0.03 14.0 0.1 2.4 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Myosin_N PF02736.14 ETO24568.1 - 0.011 15.3 0.3 0.096 12.3 0.0 2.6 2 1 0 2 2 2 0 Myosin N-terminal SH3-like domain DUF3397 PF11877.3 ETO24569.1 - 2.9 7.9 7.8 2.9 7.9 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3397) DUF937 PF06078.6 ETO24570.1 - 0.24 11.6 2.2 0.5 10.5 1.0 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF937) ubiquitin PF00240.18 ETO24571.1 - 0.056 12.8 0.1 0.34 10.3 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin family DUF1374 PF07118.6 ETO24571.1 - 0.13 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1374) CAF-1_p150 PF11600.3 ETO24572.1 - 0.66 9.3 58.2 0.014 14.7 33.5 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal UBA_4 PF14555.1 ETO24573.1 - 4.1e-08 32.6 0.0 7.4e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain IncA PF04156.9 ETO24573.1 - 0.00021 20.9 5.7 0.00021 20.9 3.9 2.5 2 1 0 2 2 2 1 IncA protein DUF2183 PF09949.4 ETO24573.1 - 0.0097 15.8 1.5 0.03 14.2 0.0 2.6 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2183) PASTA PF03793.14 ETO24573.1 - 0.047 13.3 0.0 0.47 10.1 0.0 2.5 2 0 0 2 2 2 0 PASTA domain NOP5NT PF08156.8 ETO24573.1 - 0.39 10.8 0.0 0.39 10.8 0.0 2.5 3 0 0 3 3 3 0 NOP5NT (NUC127) domain V_ATPase_I PF01496.14 ETO24573.1 - 2.6 5.7 9.8 0.38 8.5 1.4 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family CENP-H PF05837.7 ETO24573.1 - 4.5 7.5 18.1 0.11 12.6 5.6 2.7 2 0 0 2 2 2 0 Centromere protein H (CENP-H) WW PF00397.21 ETO24574.1 - 0.00016 21.4 0.1 0.00016 21.4 0.1 1.8 2 0 0 2 2 2 1 WW domain zf-RanBP PF00641.13 ETO24574.1 - 0.00068 18.6 2.9 0.0014 17.6 2.0 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DZR PF12773.2 ETO24574.1 - 0.017 14.9 1.4 0.037 13.8 0.9 1.5 1 0 0 1 1 1 0 Double zinc ribbon Astro_capsid PF03115.9 ETO24574.1 - 0.41 8.8 8.7 0.5 8.5 6.1 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor APC8 PF04049.8 ETO24575.1 - 0.073 12.7 3.6 0.26 11.0 2.5 1.9 1 1 0 1 1 1 0 Anaphase promoting complex subunit 8 / Cdc23 Porin_1 PF00267.16 ETO24575.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Gram-negative porin Chromo PF00385.19 ETO24576.1 - 6.5e-06 25.7 1.3 6.5e-06 25.7 0.9 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Mis14 PF08641.7 ETO24576.1 - 1.2 9.1 6.3 2.3 8.2 2.9 2.4 3 0 0 3 3 3 0 Kinetochore protein Mis14 like TMF_DNA_bd PF12329.3 ETO24577.1 - 0.0033 17.1 9.7 0.0033 17.1 6.7 7.5 7 2 1 8 8 8 2 TATA element modulatory factor 1 DNA binding TSC22 PF01166.13 ETO24577.1 - 0.021 14.8 0.5 0.021 14.8 0.4 7.7 7 2 2 9 9 9 0 TSC-22/dip/bun family Reo_sigmaC PF04582.7 ETO24577.1 - 1.9 7.6 18.3 0.45 9.6 0.9 4.1 2 1 2 4 4 4 0 Reovirus sigma C capsid protein FUSC PF04632.7 ETO24577.1 - 4 5.7 18.5 0.67 8.3 0.1 2.7 1 1 1 2 2 2 0 Fusaric acid resistance protein family Pox_A_type_inc PF04508.7 ETO24577.1 - 4.8 7.2 39.1 0.19 11.5 0.4 7.2 8 0 0 8 8 8 0 Viral A-type inclusion protein repeat IncA PF04156.9 ETO24577.1 - 7.1 6.1 75.3 0.33 10.5 12.3 4.0 1 1 2 3 3 3 0 IncA protein CDC45 PF02724.9 ETO24579.1 - 0.026 12.6 3.3 0.024 12.7 2.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S66 PF02016.10 ETO24579.1 - 0.06 12.2 1.6 0.083 11.8 1.1 1.2 1 0 0 1 1 1 0 LD-carboxypeptidase SR-25 PF10500.4 ETO24579.1 - 0.069 12.6 13.8 0.11 11.9 9.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NARP1 PF12569.3 ETO24579.1 - 0.075 11.7 8.9 0.1 11.3 6.2 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FLO_LFY PF01698.11 ETO24579.1 - 0.21 10.3 9.0 0.28 9.9 6.3 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein RR_TM4-6 PF06459.7 ETO24579.1 - 0.31 10.8 10.1 0.38 10.6 7.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 ETO24579.1 - 0.36 10.5 7.8 0.43 10.3 5.4 1.2 1 0 0 1 1 1 0 DDHD domain IncA PF04156.9 ETO24579.1 - 1.8 8.1 5.9 2.7 7.5 4.1 1.1 1 0 0 1 1 1 0 IncA protein RP-C_C PF11800.3 ETO24579.1 - 2.8 7.6 8.4 3.7 7.2 5.8 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Atrophin-1 PF03154.10 ETO24579.1 - 3.3 5.7 7.8 4.1 5.4 5.4 1.2 1 0 0 1 1 1 0 Atrophin-1 family HSP90 PF00183.13 ETO24579.1 - 3.5 5.9 14.9 4.7 5.4 10.4 1.1 1 0 0 1 1 1 0 Hsp90 protein Neur_chan_memb PF02932.11 ETO24579.1 - 8.5 6.1 7.2 11 5.7 5.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2956 PF11169.3 ETO24579.1 - 8.9 6.3 14.2 0.72 9.8 6.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) SNARE PF05739.14 ETO24580.1 - 2.6e-09 36.6 7.9 0.00028 20.5 0.1 3.5 3 0 0 3 3 3 2 SNARE domain BA14K PF07886.6 ETO24580.1 - 0.14 11.8 0.1 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 BA14K-like protein RXT2_N PF08595.6 ETO24581.1 - 4.2 7.1 23.9 0.9 9.3 7.8 2.9 2 1 1 3 3 3 0 RXT2-like, N-terminal DUF2457 PF10446.4 ETO24581.1 - 8.1 5.0 38.9 0.03 13.0 15.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2457) Orbi_NS3 PF01616.11 ETO24584.1 - 0.017 14.0 5.1 0.027 13.4 0.0 2.4 2 1 0 2 2 2 0 Orbivirus NS3 DUF462 PF04315.7 ETO24584.1 - 1.2 8.5 7.7 0.088 12.1 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF462 DUF4376 PF14301.1 ETO24584.1 - 2.7 8.1 8.5 0.77 9.9 0.4 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4376) Nop25 PF09805.4 ETO24584.1 - 5.2 7.1 18.4 0.15 12.1 6.1 2.2 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) TcdA_TcdB_pore PF12920.2 ETO24584.1 - 5.6 4.7 9.6 2.6 5.8 1.8 2.0 1 1 0 2 2 2 0 TcdA/TcdB pore forming domain WD40 PF00400.27 ETO24585.1 - 2.5e-65 214.1 21.5 7.5e-11 41.4 0.1 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO24585.1 - 1.8e-13 49.4 5.8 0.00084 17.5 0.0 5.4 2 2 3 5 5 5 5 Nucleoporin Nup120/160 SRI PF08236.6 ETO24587.1 - 0.0055 16.6 1.2 0.0055 16.6 0.8 2.2 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain G-alpha PF00503.15 ETO24588.1 - 2.5e-12 46.1 1.2 2.8e-12 46.0 0.8 1.1 1 0 0 1 1 1 1 G-protein alpha subunit ABC_tran PF00005.22 ETO24588.1 - 0.00042 20.6 0.1 0.00062 20.0 0.1 1.4 1 1 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.13 ETO24588.1 - 0.046 13.1 0.0 0.62 9.4 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.1 ETO24588.1 - 0.047 13.2 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.15 ETO24589.1 - 4.1e-21 75.1 2.8 2e-13 49.7 0.1 2.0 2 0 0 2 2 2 2 G-protein alpha subunit Arf PF00025.16 ETO24589.1 - 0.011 14.9 0.1 0.073 12.3 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF3671 PF12420.3 ETO24589.1 - 0.58 10.1 6.2 0.86 9.6 3.9 1.6 1 1 0 1 1 1 0 Protein of unknown function WD40 PF00400.27 ETO24590.1 - 4.8e-63 206.9 35.9 9.4e-11 41.1 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO24590.1 - 2.6e-08 32.4 13.6 0.0011 17.2 0.6 5.0 1 1 3 5 5 5 5 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO24590.1 - 0.035 13.4 5.6 0.047 12.9 0.4 3.0 1 1 4 5 5 5 0 Domain of unknown function (DUF4221) WD40 PF00400.27 ETO24592.1 - 2.4e-12 46.1 1.3 5e-11 42.0 0.0 2.3 2 1 0 2 2 2 1 WD domain, G-beta repeat BBS2_Mid PF14783.1 ETO24592.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.7 1 1 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region CAF1 PF04857.15 ETO24593.1 - 4.7e-09 35.9 0.4 0.0016 17.7 0.0 2.3 2 0 0 2 2 2 2 CAF1 family ribonuclease FAM176 PF14851.1 ETO24594.1 - 0.015 14.9 0.0 0.042 13.5 0.0 1.7 1 0 0 1 1 1 0 FAM176 family BRE1 PF08647.6 ETO24596.1 - 0.12 12.4 0.2 0.12 12.4 0.1 4.8 2 1 2 4 4 4 0 BRE1 E3 ubiquitin ligase FERM_N PF09379.5 ETO24596.1 - 0.95 9.5 8.6 32 4.6 6.0 2.6 1 1 0 1 1 1 0 FERM N-terminal domain Lipoprotein_6 PF01441.14 ETO24596.1 - 4.4 7.1 35.9 0.069 12.9 5.8 3.5 2 1 2 4 4 4 0 Lipoprotein S_layer_N PF05123.7 ETO24596.1 - 6.6 6.2 8.5 6.9 6.2 5.1 1.6 1 1 0 1 1 1 0 S-layer like family, N-terminal region Reo_sigmaC PF04582.7 ETO24596.1 - 8.2 5.4 12.3 1.2 8.1 4.3 2.4 2 1 1 3 3 3 0 Reovirus sigma C capsid protein PX PF00787.19 ETO24597.1 - 5.3e-06 26.2 0.2 1.6e-05 24.6 0.2 1.8 1 0 0 1 1 1 1 PX domain Herpes_LAMP2 PF06126.6 ETO24597.1 - 0.062 11.7 2.1 0.093 11.1 1.4 1.2 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 Macoilin PF09726.4 ETO24597.1 - 2.9 6.0 12.8 3.8 5.6 8.9 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4325 PF14213.1 ETO24598.1 - 0.0053 16.3 0.1 1.8 8.2 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF4325) Ferritin PF00210.19 ETO24599.1 - 0.089 12.5 3.8 2.5 7.8 1.0 2.1 1 1 1 2 2 2 0 Ferritin-like domain FdhE PF04216.7 ETO24599.1 - 0.11 12.1 0.3 0.13 11.9 0.2 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation RRM_1 PF00076.17 ETO24600.1 - 8e-21 73.4 0.0 8.7e-14 50.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO24600.1 - 8.1e-15 54.5 0.0 3.9e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO24600.1 - 4e-07 29.7 0.0 0.00031 20.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 ETO24600.1 - 0.12 12.1 5.1 0.24 11.1 3.6 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Mucin PF01456.12 ETO24601.1 - 6.2 6.5 23.6 9.9 5.9 16.4 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein WD40 PF00400.27 ETO24602.1 - 0.002 17.9 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 WD domain, G-beta repeat Phycobilisome PF00502.14 ETO24602.1 - 0.24 11.1 3.3 0.4 10.4 2.3 1.3 1 0 0 1 1 1 0 Phycobilisome protein WD40 PF00400.27 ETO24603.1 - 3e-06 26.9 0.2 6.9e-06 25.7 0.2 1.7 1 0 0 1 1 1 1 WD domain, G-beta repeat SR-25 PF10500.4 ETO24603.1 - 0.004 16.6 13.2 0.004 16.6 9.2 1.6 1 1 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF3633 PF12315.3 ETO24603.1 - 0.16 11.2 2.6 0.36 10.1 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3633) DUF3446 PF11928.3 ETO24603.1 - 0.4 10.8 10.9 0.096 12.8 5.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Macoilin PF09726.4 ETO24603.1 - 2 6.6 14.5 3.2 5.9 10.1 1.3 1 0 0 1 1 1 0 Transmembrane protein WD40 PF00400.27 ETO24604.1 - 1.5e-59 195.8 22.9 4.1e-11 42.3 0.4 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO24604.1 - 1.2e-09 36.9 6.3 0.1 10.7 0.1 5.8 3 2 3 6 6 6 5 Nucleoporin Nup120/160 Rieske_2 PF13806.1 ETO24604.1 - 0.027 14.1 0.0 0.32 10.7 0.0 2.6 3 0 0 3 3 3 0 Rieske-like [2Fe-2S] domain DUF851 PF05867.6 ETO24604.1 - 0.12 11.5 0.0 0.98 8.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF851) HAD PF12710.2 ETO24604.1 - 0.99 9.5 4.2 8.3 6.5 0.0 2.8 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase WD40 PF00400.27 ETO24605.1 - 2e-58 192.3 16.3 1.4e-10 40.5 0.1 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO24605.1 - 3.9e-13 48.3 7.8 0.00053 18.2 0.1 5.7 3 3 2 5 5 5 5 Nucleoporin Nup120/160 Pkinase PF00069.20 ETO24606.1 - 3e-55 187.1 0.1 3.7e-55 186.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO24606.1 - 2.1e-37 128.6 0.0 2.5e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO24606.1 - 3.3e-06 26.2 0.0 3.8e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 ETO24606.1 - 6.2e-05 22.4 0.1 8.9e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 ETO24606.1 - 0.00036 20.3 0.0 0.00056 19.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 ETO24606.1 - 0.0024 16.9 0.1 0.0038 16.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.4 ETO24606.1 - 0.0026 16.4 0.2 0.0042 15.7 0.1 1.3 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC YrbL-PhoP_reg PF10707.4 ETO24606.1 - 0.0049 16.2 0.1 0.016 14.5 0.0 1.8 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 ETO24606.1 - 0.032 13.8 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1345 PF07077.6 ETO24606.1 - 0.085 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) DUF4448 PF14610.1 ETO24608.1 - 0.015 14.8 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Herpes_capsid PF06112.6 ETO24608.1 - 0.084 12.9 1.9 0.13 12.3 0.3 1.9 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Vpu PF00558.14 ETO24608.1 - 2.9 7.5 4.6 0.68 9.5 0.4 2.1 2 0 0 2 2 2 0 Vpu protein Afaf PF15339.1 ETO24610.1 - 0.2 11.2 2.3 10 5.6 0.2 2.8 3 0 0 3 3 3 0 Acrosome formation-associated factor DUF4400 PF14348.1 ETO24611.1 - 4.9 6.4 6.8 0.51 9.6 1.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) Pkinase PF00069.20 ETO24613.1 - 6.6e-73 245.0 0.0 2.2e-72 243.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO24613.1 - 3.8e-35 121.2 0.0 1.1e-29 103.3 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.18 ETO24613.1 - 4.8e-05 23.2 0.0 0.00084 19.1 0.0 2.5 2 1 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 ETO24613.1 - 0.00084 18.3 0.0 0.0021 17.0 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETO24613.1 - 0.0015 17.6 0.5 0.0065 15.5 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 ETO24613.1 - 0.011 15.0 0.4 0.023 14.0 0.2 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL SR-25 PF10500.4 ETO24614.1 - 2.5 7.5 22.9 0.11 11.9 9.4 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Neur_chan_memb PF02932.11 ETO24614.1 - 8.2 6.2 7.1 11 5.8 4.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region WD40 PF00400.27 ETO24615.1 - 1.7e-88 287.6 25.4 4.6e-14 51.6 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO24615.1 - 5.6e-17 62.0 3.5 2.3e-05 24.1 0.0 3.7 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO24615.1 - 4.7e-07 29.3 9.3 8.4 6.1 0.1 6.7 7 0 0 7 7 7 4 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO24615.1 - 7.6e-06 24.4 0.1 0.059 11.6 0.0 2.8 1 1 1 2 2 2 2 Cytochrome D1 heme domain Resistin PF06954.6 ETO24615.1 - 4.3e-05 23.7 7.0 1.7 8.9 0.2 5.5 1 1 5 6 6 6 1 Resistin DPPIV_N PF00930.16 ETO24615.1 - 0.00014 20.5 0.2 3.2 6.2 0.0 4.5 1 1 4 5 5 5 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nucleoporin_N PF08801.6 ETO24615.1 - 0.00016 20.5 7.7 0.34 9.6 0.2 4.8 1 1 3 4 4 4 2 Nup133 N terminal like DUF1258 PF06869.7 ETO24615.1 - 0.018 14.1 3.0 18 4.3 0.0 3.9 1 1 4 5 5 5 0 Protein of unknown function (DUF1258) Str_synth PF03088.11 ETO24615.1 - 0.027 14.4 0.0 20 5.2 0.0 3.6 2 1 2 4 4 4 0 Strictosidine synthase DnaJ PF00226.26 ETO24618.1 - 4.8e-14 51.8 0.5 1.1e-13 50.6 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain C9orf72-like PF15019.1 ETO24621.1 - 1.2e-21 77.0 0.2 4.2e-20 71.9 0.0 2.4 2 0 0 2 2 2 2 C9orf72-like protein family DUF3395 PF11875.3 ETO24622.1 - 7.5e-07 28.8 1.3 2.3e-06 27.2 0.9 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3395) RFXA_RFXANK_bdg PF15289.1 ETO24622.1 - 2.5 8.2 11.0 0.18 11.9 0.7 2.1 2 0 0 2 2 2 0 Regulatory factor X-associated C-terminal binding domain ARF7EP_C PF14949.1 ETO24622.1 - 2.6 8.5 7.7 8.6 6.8 0.2 2.2 2 0 0 2 2 2 0 ARF7 effector protein C-terminus Apis_Csd PF11671.3 ETO24622.1 - 3.1 7.5 10.7 0.17 11.6 2.7 2.0 2 0 0 2 2 2 0 Complementary sex determiner protein Methyltransf_11 PF08241.7 ETO24623.1 - 0.00014 22.2 0.0 0.00028 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF4371 PF14291.1 ETO24623.1 - 0.0031 17.1 1.1 0.0048 16.4 0.6 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4371) FGF PF00167.13 ETO24623.1 - 0.017 14.8 0.4 0.029 14.1 0.3 1.4 1 0 0 1 1 1 0 Fibroblast growth factor TnpV PF14198.1 ETO24623.1 - 0.067 13.0 0.9 0.13 12.1 0.5 1.5 1 1 0 1 1 1 0 Transposon-encoded protein TnpV Abi PF02517.11 ETO24624.1 - 0.95 9.6 9.5 0.53 10.4 4.1 2.1 2 1 0 2 2 2 0 CAAX protease self-immunity DUF592 PF04574.8 ETO24625.1 - 0.12 11.9 1.2 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF592) MAP65_ASE1 PF03999.7 ETO24626.1 - 0.00034 19.3 0.3 0.00034 19.3 0.2 2.0 2 0 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) SOBP PF15279.1 ETO24627.1 - 7.7 6.8 13.4 1.5 9.0 6.7 1.7 1 1 0 1 1 1 0 Sine oculis-binding protein Caldesmon PF02029.10 ETO24628.1 - 0.017 13.6 18.1 0.017 13.5 12.6 1.2 1 0 0 1 1 1 0 Caldesmon Borrelia_P83 PF05262.6 ETO24628.1 - 0.021 13.1 17.0 0.022 13.0 11.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein TOM_sub5 PF15178.1 ETO24628.1 - 0.05 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM5 homolog Vfa1 PF08432.5 ETO24628.1 - 0.18 11.8 23.9 0.31 11.0 16.6 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1510 PF07423.6 ETO24628.1 - 0.56 9.5 23.2 0.9 8.8 16.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF702 PF05142.7 ETO24628.1 - 0.62 10.2 6.8 0.14 12.3 2.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF702) DUF4551 PF15087.1 ETO24628.1 - 0.69 8.2 7.7 0.75 8.0 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CDC45 PF02724.9 ETO24628.1 - 0.92 7.4 14.1 0.95 7.4 9.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 ETO24628.1 - 1.1 6.8 14.6 1.2 6.7 10.1 1.1 1 0 0 1 1 1 0 Ycf1 Tom37_C PF11801.3 ETO24628.1 - 1.2 8.9 8.9 1.6 8.5 6.0 1.3 1 1 0 1 1 1 0 Tom37 C-terminal domain U79_P34 PF03064.11 ETO24628.1 - 1.3 8.4 15.6 2.2 7.7 10.8 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Trypan_PARP PF05887.6 ETO24628.1 - 2.2 8.0 11.1 3.1 7.6 7.7 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RR_TM4-6 PF06459.7 ETO24628.1 - 2.3 8.0 20.4 3.2 7.5 14.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.3 ETO24628.1 - 2.4 6.6 14.2 4 5.9 9.8 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Peptidase_U57 PF05582.7 ETO24628.1 - 3.2 6.6 8.6 4.7 6.0 6.0 1.3 1 0 0 1 1 1 0 YabG peptidase U57 Neur_chan_memb PF02932.11 ETO24628.1 - 4.3 7.1 6.3 5 6.9 4.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MIP-T3 PF10243.4 ETO24628.1 - 4.4 5.6 33.2 7 4.9 23.0 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Sec62 PF03839.11 ETO24628.1 - 4.5 6.6 19.4 6.8 6.0 13.4 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 GAGA_bind PF06217.7 ETO24628.1 - 7.8 6.3 15.4 11 5.8 10.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family PRP21_like_P PF12230.3 ETO24628.1 - 8.2 5.8 25.5 1.4 8.3 15.1 1.5 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein YqfQ PF14181.1 ETO24628.1 - 9.3 6.2 20.6 19 5.2 14.3 1.5 1 0 0 1 1 1 0 YqfQ-like protein Pox_A_type_inc PF04508.7 ETO24629.1 - 0.092 12.5 2.1 0.3 10.9 1.5 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DUF2722 PF10846.3 ETO24629.1 - 0.1 11.5 27.1 0.64 8.9 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) PUB PF09409.5 ETO24631.1 - 0.00055 19.6 3.4 0.0014 18.3 0.3 2.9 2 2 0 2 2 2 1 PUB domain CUE PF02845.11 ETO24631.1 - 0.0021 17.5 0.1 0.0021 17.5 0.1 2.2 2 0 0 2 2 2 1 CUE domain PCI PF01399.22 ETO24631.1 - 0.0078 16.5 3.4 0.0083 16.4 0.9 2.1 1 1 1 2 2 2 1 PCI domain Phosphoesterase PF04185.9 ETO24632.1 - 4.6e-30 105.0 0.1 5.9e-30 104.7 0.1 1.1 1 0 0 1 1 1 1 Phosphoesterase family LRR_7 PF13504.1 ETO24633.1 - 0.023 14.8 0.9 0.43 10.9 0.1 3.5 2 0 0 2 2 2 0 Leucine rich repeat LRR_2 PF07723.8 ETO24633.1 - 0.032 14.7 0.2 0.11 12.9 0.1 2.1 1 0 0 1 1 1 0 Leucine Rich Repeat Baseplate_J PF04865.9 ETO24633.1 - 0.18 11.0 0.1 0.25 10.6 0.0 1.1 1 0 0 1 1 1 0 Baseplate J-like protein LRR_4 PF12799.2 ETO24633.1 - 0.53 9.9 5.4 0.89 9.2 0.1 3.4 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 ETO24633.1 - 2.3 8.5 7.0 3.5 7.9 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich repeat adh_short PF00106.20 ETO24635.1 - 2.6e-17 63.2 0.0 3.5e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETO24635.1 - 4.5e-07 29.7 0.0 6.8e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETO24635.1 - 1.2e-05 25.2 0.0 1.6e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 ETO24635.1 - 0.00081 18.3 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein WD40 PF00400.27 ETO24636.1 - 4e-150 482.9 46.4 1.4e-11 43.7 0.1 14.6 14 0 0 14 14 14 14 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO24636.1 - 4.4e-10 38.4 6.4 0.054 11.7 0.1 6.1 3 2 2 6 6 6 4 Cytochrome D1 heme domain NACHT PF05729.7 ETO24636.1 - 3e-07 30.2 0.0 6.7e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Pentapeptide PF00805.17 ETO24636.1 - 5.3e-07 28.7 0.9 1e-06 27.8 0.6 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Mid2 PF04478.7 ETO24636.1 - 0.00047 19.5 1.1 0.38 10.1 0.0 4.8 3 1 1 4 4 4 1 Mid2 like cell wall stress sensor Pentapeptide_4 PF13599.1 ETO24636.1 - 0.00056 19.6 1.7 0.00085 19.0 0.2 2.0 2 0 0 2 2 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 ETO24636.1 - 0.0014 18.4 1.4 0.0065 16.3 0.1 2.8 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) AAA_22 PF13401.1 ETO24636.1 - 0.0017 18.5 0.0 0.0058 16.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain PD40 PF07676.7 ETO24636.1 - 0.0047 16.5 17.0 6.2 6.6 0.1 7.5 9 0 0 9 9 9 1 WD40-like Beta Propeller Repeat AAA_18 PF13238.1 ETO24636.1 - 0.0075 16.5 0.1 0.065 13.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 ETO24636.1 - 0.01 15.8 0.0 2.1 8.3 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain Proteasome_A_N PF10584.4 ETO24636.1 - 0.017 14.4 10.0 6.5 6.1 0.0 5.8 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature AAA PF00004.24 ETO24636.1 - 0.036 14.2 0.0 0.72 10.0 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 ETO24636.1 - 0.055 13.0 0.1 0.32 10.6 0.0 2.3 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 ETO24636.1 - 0.065 14.0 0.1 0.25 12.1 0.0 2.1 2 0 0 2 2 1 0 AAA domain ArabFuran-catal PF09206.6 ETO24636.1 - 0.14 11.0 0.4 16 4.3 0.1 2.7 2 0 0 2 2 2 0 Alpha-L-arabinofuranosidase B, catalytic MFS_1 PF07690.11 ETO24638.1 - 0.0056 15.4 0.6 0.052 12.2 0.0 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MatE PF01554.13 ETO24639.1 - 2.7e-30 105.1 21.4 9.9e-18 64.2 2.9 3.0 3 0 0 3 3 3 2 MatE AzlD PF05437.7 ETO24639.1 - 8.6 6.3 16.0 0.2 11.5 2.9 3.2 3 1 0 4 4 4 0 Branched-chain amino acid transport protein (AzlD) PBP1_TM PF14812.1 ETO24640.1 - 0.23 11.7 0.1 0.23 11.7 0.1 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CKAP2_C PF15297.1 ETO24640.1 - 0.67 8.7 5.7 0.86 8.3 4.0 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Utp14 PF04615.8 ETO24640.1 - 1.7 6.7 12.0 2.1 6.4 8.3 1.0 1 0 0 1 1 1 0 Utp14 protein ATP-synt_S1 PF05827.7 ETO24641.1 - 0.088 12.1 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) SAC3_GANP PF03399.11 ETO24642.1 - 2.9e-40 138.0 9.2 6.1e-40 136.9 6.4 1.5 1 1 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 ETO24642.1 - 1.6e-06 27.9 0.5 3.9e-06 26.6 0.3 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Mad3_BUB1_I PF08311.7 ETO24644.1 - 2.1e-11 43.7 2.2 4e-11 42.7 0.7 2.0 1 1 0 1 1 1 1 Mad3/BUB1 homology region 1 W2 PF02020.13 ETO24644.1 - 4 7.4 6.6 35 4.4 0.0 2.8 2 1 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon Abhydrolase_5 PF12695.2 ETO24645.1 - 1e-08 35.0 0.0 1.4e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETO24645.1 - 4.1e-05 23.5 0.1 5.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2457 PF10446.4 ETO24645.1 - 0.013 14.2 1.0 0.013 14.2 0.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Abhydrolase_3 PF07859.8 ETO24645.1 - 0.014 14.9 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold AIF_C PF14721.1 ETO24645.1 - 0.87 9.8 8.0 18 5.5 3.1 2.3 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SelP_N PF04592.9 ETO24645.1 - 3.3 7.0 23.4 0.47 9.8 12.7 1.9 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Zip PF02535.17 ETO24645.1 - 4.2 6.2 17.4 8.4 5.2 12.1 1.6 1 1 0 1 1 1 0 ZIP Zinc transporter Sporozoite_P67 PF05642.6 ETO24648.1 - 0.17 9.7 15.5 0.25 9.1 10.8 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RRN3 PF05327.6 ETO24648.1 - 0.82 7.7 3.9 0.9 7.5 2.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Trypan_PARP PF05887.6 ETO24648.1 - 2.2 8.0 9.9 4.1 7.2 6.9 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4637 PF15470.1 ETO24648.1 - 4 7.0 6.2 6.7 6.3 4.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Dicty_REP PF05086.7 ETO24648.1 - 6.5 4.3 20.4 8 4.0 14.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CAF-1_p150 PF11600.3 ETO24649.1 - 9.4e-06 25.1 45.1 9.4e-06 25.1 31.3 4.7 3 2 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DnaJ PF00226.26 ETO24650.1 - 5.4e-13 48.4 4.0 1e-12 47.6 2.8 1.5 1 0 0 1 1 1 1 DnaJ domain YccV-like PF08755.6 ETO24650.1 - 0.04 13.8 0.9 0.04 13.8 0.6 2.0 1 1 0 2 2 2 0 Hemimethylated DNA-binding protein YccV like Complex1_30kDa PF00329.14 ETO24652.1 - 3.9e-23 81.6 0.2 1e-22 80.3 0.0 1.7 2 0 0 2 2 2 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DUF4525 PF15027.1 ETO24653.1 - 0.039 13.4 0.4 0.73 9.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) TPR_4 PF07721.9 ETO24654.1 - 0.015 15.6 0.1 0.083 13.3 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETO24654.1 - 0.016 14.9 2.2 13 5.8 0.1 4.3 3 2 0 3 3 3 0 Tetratricopeptide repeat Clathrin PF00637.15 ETO24654.1 - 0.036 13.6 0.3 0.036 13.6 0.2 3.1 3 1 0 3 3 3 0 Region in Clathrin and VPS CPSase_L_D2 PF02786.12 ETO24655.1 - 1.9e-85 285.4 0.1 1.2e-55 188.0 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 ETO24655.1 - 2.2e-42 143.6 0.2 5.9e-42 142.3 0.1 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 ETO24655.1 - 8.2e-21 74.5 0.1 1.3e-17 64.1 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.17 ETO24655.1 - 2.7e-18 65.6 0.0 8.1e-18 64.1 0.0 1.9 1 0 0 1 1 1 1 MGS-like domain ATPgrasp_Ter PF15632.1 ETO24655.1 - 5.5e-17 61.5 0.0 3e-10 39.3 0.0 2.6 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_chain PF00289.17 ETO24655.1 - 3.6e-13 49.5 0.0 1.3e-12 47.7 0.0 2.1 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp PF02222.17 ETO24655.1 - 6.7e-10 38.5 0.0 1.4e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 ETO24655.1 - 3e-07 30.0 0.1 1.4e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus RimK PF08443.6 ETO24655.1 - 1e-06 28.4 0.1 4.8e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 ETO24655.1 - 0.00091 19.1 0.1 0.11 12.4 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain MIP-T3 PF10243.4 ETO24656.1 - 0.0006 18.4 9.4 0.00065 18.2 6.5 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 EPL1 PF10513.4 ETO24656.1 - 0.0098 16.1 4.1 0.0098 16.1 2.8 1.5 2 0 0 2 2 1 1 Enhancer of polycomb-like Protocadherin PF08374.6 ETO24656.1 - 0.035 13.7 10.3 0.07 12.7 7.1 1.5 1 0 0 1 1 1 0 Protocadherin Cnd1_N PF12922.2 ETO24656.1 - 0.04 13.5 7.8 0.21 11.2 3.8 2.1 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term 7tm_1 PF00001.16 ETO24656.1 - 0.042 12.9 2.2 0.19 10.8 0.3 2.1 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) SHR3_chaperone PF08229.6 ETO24656.1 - 0.046 12.6 1.9 0.081 11.8 1.3 1.4 1 0 0 1 1 1 0 ER membrane protein SH3 DUF2015 PF09435.5 ETO24656.1 - 0.054 13.2 0.4 0.67 9.7 0.1 2.1 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF2015) DUF788 PF05620.6 ETO24656.1 - 0.066 13.0 5.2 0.068 13.0 2.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF788) OSTbeta PF15048.1 ETO24656.1 - 0.093 12.8 2.9 0.2 11.7 2.0 1.5 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Neur_chan_memb PF02932.11 ETO24656.1 - 0.11 12.4 3.0 0.16 11.8 2.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PIG-P PF08510.7 ETO24656.1 - 0.11 12.0 0.0 15 5.2 0.0 2.2 2 0 0 2 2 2 0 PIG-P Folate_carrier PF01770.13 ETO24656.1 - 0.19 10.2 2.4 0.11 10.9 0.3 1.5 2 0 0 2 2 2 0 Reduced folate carrier Vfa1 PF08432.5 ETO24656.1 - 0.26 11.3 17.6 0.029 14.4 9.2 1.5 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 OAD_gamma PF04277.8 ETO24656.1 - 0.41 11.0 7.4 0.79 10.1 5.1 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain U79_P34 PF03064.11 ETO24656.1 - 0.53 9.7 11.5 0.94 8.9 8.0 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Bap31 PF05529.7 ETO24656.1 - 0.58 9.5 8.6 1.1 8.6 6.0 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Ctr PF04145.10 ETO24656.1 - 1.2 9.2 5.7 5.7 6.9 3.4 2.0 1 1 1 2 2 2 0 Ctr copper transporter family DUF3987 PF13148.1 ETO24656.1 - 1.3 7.5 9.0 1.7 7.1 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Conotoxin PF02950.12 ETO24656.1 - 1.6 9.6 10.2 8.3 7.2 6.2 2.7 2 1 0 2 2 2 0 Conotoxin FAM176 PF14851.1 ETO24656.1 - 1.7 8.3 4.4 0.46 10.1 0.8 1.6 2 0 0 2 2 2 0 FAM176 family YMF19 PF02326.10 ETO24656.1 - 2.2 8.8 9.2 9.8 6.8 3.5 2.5 2 0 0 2 2 2 0 Plant ATP synthase F0 Otopetrin PF03189.8 ETO24656.1 - 2.5 7.0 5.1 1.6 7.6 1.3 1.7 1 1 2 3 3 3 0 Otopetrin EphA2_TM PF14575.1 ETO24656.1 - 5.8 7.3 10.8 14 6.2 6.1 2.4 2 1 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain Rota_VP2 PF05087.7 ETO24656.1 - 7.2 4.3 9.3 45 1.7 6.5 1.8 2 0 0 2 2 2 0 Rotavirus VP2 protein ETRAMP PF09716.5 ETO24656.1 - 7.8 6.5 19.3 7.4 6.6 12.0 1.9 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) SR-25 PF10500.4 ETO24656.1 - 8 5.8 32.6 0.21 11.0 17.1 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Beta-lactamase PF00144.19 ETO24657.1 - 1.7e-43 148.9 0.0 2e-43 148.6 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase ORC6 PF05460.8 ETO24658.1 - 0.064 12.3 16.7 0.075 12.1 11.6 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Nop14 PF04147.7 ETO24658.1 - 0.12 10.3 29.3 0.12 10.3 20.3 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.10 ETO24658.1 - 0.37 9.3 19.3 0.41 9.2 13.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Daxx PF03344.10 ETO24658.1 - 0.46 8.9 29.4 0.46 8.9 20.4 1.1 1 0 0 1 1 1 0 Daxx Family Neur_chan_memb PF02932.11 ETO24658.1 - 1.2 8.9 11.9 1.5 8.6 8.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ycf1 PF05758.7 ETO24658.1 - 2.6 5.6 21.6 2.8 5.5 15.0 1.2 1 0 0 1 1 1 0 Ycf1 Ebola_NP PF05505.7 ETO24658.1 - 3.8 5.4 18.4 3.9 5.4 12.8 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Borrelia_P83 PF05262.6 ETO24658.1 - 4.7 5.3 27.0 4.7 5.3 18.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4211 PF13926.1 ETO24660.1 - 0.037 13.4 1.3 0.06 12.7 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4211) RRM_1 PF00076.17 ETO24661.1 - 9.6e-05 21.9 0.0 0.00023 20.7 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SDF PF00375.13 ETO24661.1 - 0.017 13.8 0.0 0.022 13.5 0.0 1.1 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family RRM_6 PF14259.1 ETO24661.1 - 0.018 15.0 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1161 PF06649.7 ETO24661.1 - 0.037 13.9 0.2 0.086 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1161) ubiquitin PF00240.18 ETO24662.1 - 7.8e-28 95.6 0.1 1.7e-27 94.6 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 ETO24662.1 - 2.3e-16 59.2 0.1 6.7e-16 57.7 0.1 1.9 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 ETO24662.1 - 6e-06 26.4 0.1 3.2e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-like domain Hom_end_hint PF05203.11 ETO24662.1 - 0.0001 22.1 0.0 0.0001 22.1 0.0 2.8 3 0 0 3 3 3 1 Hom_end-associated Hint Hint PF01079.15 ETO24662.1 - 0.00099 18.3 0.0 0.0021 17.2 0.0 1.4 1 0 0 1 1 1 1 Hint module DUF2870 PF11069.3 ETO24662.1 - 0.023 14.7 2.8 0.046 13.7 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2870) Hint_2 PF13403.1 ETO24662.1 - 0.04 13.8 0.0 0.084 12.8 0.0 1.5 1 0 0 1 1 1 0 Hint domain FAM176 PF14851.1 ETO24662.1 - 0.077 12.6 3.2 0.11 12.1 0.6 2.2 2 0 0 2 2 2 0 FAM176 family AXH PF08517.7 ETO24662.1 - 0.32 11.1 2.8 0.49 10.5 0.0 2.7 4 0 0 4 4 4 0 Ataxin-1 and HBP1 module (AXH) Rad60-SLD_2 PF13881.1 ETO24662.1 - 0.43 10.4 0.0 0.43 10.4 0.0 3.1 3 1 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like Sigma70_ner PF04546.8 ETO24662.1 - 0.47 10.0 10.1 0.026 14.1 3.0 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region FLO_LFY PF01698.11 ETO24662.1 - 0.57 8.9 6.0 2 7.1 4.3 1.7 2 0 0 2 2 2 0 Floricaula / Leafy protein DUF4337 PF14235.1 ETO24664.1 - 0.044 13.6 0.2 0.062 13.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) CbtA PF09490.5 ETO24664.1 - 0.1 11.9 0.7 0.12 11.7 0.5 1.1 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) DUF106 PF01956.11 ETO24664.1 - 0.17 11.3 1.0 0.23 10.9 0.6 1.3 1 1 0 1 1 1 0 Integral membrane protein DUF106 Mucin PF01456.12 ETO24664.1 - 0.24 11.1 16.6 0.28 10.9 11.5 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein CDC45 PF02724.9 ETO24664.1 - 0.38 8.7 6.6 0.41 8.6 4.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S64 PF08192.6 ETO24664.1 - 0.43 8.8 12.8 0.43 8.8 8.9 1.0 1 0 0 1 1 1 0 Peptidase family S64 Plasmodium_Vir PF05795.6 ETO24664.1 - 1 8.4 6.1 1.2 8.2 4.3 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein BSP_II PF05432.6 ETO24664.1 - 1.9 7.7 12.5 2.4 7.3 8.7 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF2500 PF10694.4 ETO24664.1 - 2.2 8.2 4.9 1.3 9.0 2.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2500) Sigma70_ner PF04546.8 ETO24664.1 - 2.5 7.6 10.9 0.15 11.6 3.6 1.7 1 1 1 2 2 2 0 Sigma-70, non-essential region Pex14_N PF04695.8 ETO24664.1 - 3.8 7.5 7.5 3.2 7.7 4.2 1.6 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2890 PF11081.3 ETO24664.1 - 3.8 7.5 12.6 4.7 7.2 8.7 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) PX PF00787.19 ETO24665.1 - 5.8e-15 55.0 0.5 1.2e-14 54.0 0.3 1.5 1 0 0 1 1 1 1 PX domain DUF4106 PF13388.1 ETO24665.1 - 0.8 8.5 6.4 1.5 7.6 4.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4106) Kelch_6 PF13964.1 ETO24666.1 - 1e-16 60.2 2.8 0.00015 21.7 0.0 6.2 5 1 1 6 6 6 3 Kelch motif Kelch_3 PF13415.1 ETO24666.1 - 4.1e-16 58.6 0.1 0.00011 22.2 0.0 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO24666.1 - 1.5e-15 56.6 0.1 0.0047 16.6 0.0 5.5 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO24666.1 - 1.5e-12 46.8 7.1 9.1e-05 21.9 0.0 6.3 6 1 0 6 6 6 2 Kelch motif Kelch_5 PF13854.1 ETO24666.1 - 6.1e-11 42.0 0.0 0.00036 20.4 0.0 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO24666.1 - 1.4e-05 24.6 0.1 0.87 9.4 0.0 4.2 4 1 0 4 4 4 2 Kelch motif DUF1392 PF07154.6 ETO24666.1 - 0.018 14.9 0.7 0.06 13.2 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1392) PfUIS3 PF11567.3 ETO24666.1 - 0.071 13.2 0.1 0.89 9.7 0.0 2.6 2 1 0 2 2 2 0 Plasmodium falciparum UIS3 membrane protein Mcm10 PF09332.6 ETO24667.1 - 0.32 10.3 11.9 0.38 10.0 8.3 1.1 1 0 0 1 1 1 0 Mcm10 replication factor OEP PF02321.13 ETO24667.1 - 0.48 10.0 7.5 1.1 8.8 5.2 1.5 1 0 0 1 1 1 0 Outer membrane efflux protein MIP-T3 PF10243.4 ETO24668.1 - 8.1 4.7 52.8 11 4.3 36.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 TPR_11 PF13414.1 ETO24670.1 - 3.7e-05 23.2 0.6 0.0001 21.8 0.4 1.7 1 0 0 1 1 1 1 TPR repeat TPR_19 PF14559.1 ETO24670.1 - 8e-05 22.9 0.2 0.00013 22.1 0.2 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO24670.1 - 0.00022 21.8 0.0 0.00037 21.0 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_20 PF14561.1 ETO24670.1 - 0.0014 18.6 0.1 0.0034 17.4 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO24670.1 - 0.0034 17.4 0.0 0.014 15.4 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO24670.1 - 0.0036 17.1 0.3 0.066 13.1 0.0 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO24670.1 - 0.0067 15.9 2.4 0.054 13.1 0.3 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO24670.1 - 0.013 15.4 0.2 0.031 14.2 0.1 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat Apc3 PF12895.2 ETO24670.1 - 0.018 15.1 1.2 0.018 15.1 0.9 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Spore_II_R PF09551.5 ETO24670.1 - 0.026 14.5 0.2 0.049 13.6 0.1 1.4 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) TPR_8 PF13181.1 ETO24670.1 - 0.091 12.5 1.3 0.37 10.6 0.3 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Sec7 PF01369.15 ETO24671.1 - 8.9e-57 191.8 6.6 1.9e-56 190.7 4.6 1.6 1 0 0 1 1 1 1 Sec7 domain Phage_GP20 PF06810.6 ETO24671.1 - 0.023 14.1 2.3 0.073 12.5 0.2 2.5 2 0 0 2 2 2 0 Phage minor structural protein GP20 Nucleoplasmin PF03066.10 ETO24672.1 - 7.2 6.1 11.3 18 4.8 7.8 1.6 1 0 0 1 1 1 0 Nucleoplasmin Homeobox_KN PF05920.6 ETO24673.1 - 4.3e-14 51.9 0.2 7.7e-14 51.1 0.1 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 ETO24673.1 - 6.2e-09 35.3 0.7 1.1e-08 34.5 0.5 1.4 1 0 0 1 1 1 1 Homeobox domain RNA_pol_Rpc4 PF05132.9 ETO24674.1 - 0.14 12.1 0.2 0.19 11.7 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Conotoxin PF02950.12 ETO24674.1 - 0.2 12.4 0.0 0.2 12.4 0.0 2.1 2 1 1 3 3 3 0 Conotoxin FliT PF05400.8 ETO24676.1 - 0.26 11.7 9.2 0.52 10.7 6.4 1.5 1 0 0 1 1 1 0 Flagellar protein FliT DUF4246 PF14033.1 ETO24677.1 - 2.5e-90 303.4 11.5 4.2e-49 167.5 0.5 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 ETO24677.1 - 3.7e-05 23.9 0.1 0.00017 21.7 0.1 2.1 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase DAP_C PF07932.7 ETO24677.1 - 0.099 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 D-aminopeptidase, domain C DUF1400 PF07176.6 ETO24677.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1400) G-alpha PF00503.15 ETO24678.1 - 2.9e-44 151.3 3.7 3.6e-44 151.0 2.6 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO24678.1 - 5.7e-07 28.9 0.2 1.5e-06 27.5 0.1 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family DUF3537 PF12056.3 ETO24678.1 - 0.054 12.2 2.2 0.078 11.6 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) Kelch_6 PF13964.1 ETO24679.1 - 1.1e-05 25.3 0.2 0.00041 20.4 0.0 2.7 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO24679.1 - 0.00032 20.7 0.0 0.022 14.9 0.0 3.1 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO24679.1 - 0.0075 16.0 0.5 0.1 12.4 0.0 2.8 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.20 ETO24679.1 - 0.018 14.5 4.7 0.019 14.5 0.6 2.5 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.1 ETO24679.1 - 0.42 10.6 2.9 1 9.3 0.0 2.8 4 0 0 4 4 4 0 Kelch motif G-alpha PF00503.15 ETO24680.1 - 6.9e-18 64.4 8.8 1.6e-16 60.0 6.1 2.0 1 1 0 1 1 1 1 G-protein alpha subunit LAGLIDADG_1 PF00961.14 ETO24680.1 - 0.64 10.6 4.7 0.18 12.3 0.3 2.2 2 1 0 2 2 2 0 LAGLIDADG endonuclease Pkinase PF00069.20 ETO24681.1 - 1.4e-53 181.6 0.0 6.3e-46 156.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO24681.1 - 1.5e-24 86.5 0.0 1.7e-21 76.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 ETO24681.1 - 0.064 12.2 0.0 0.11 11.4 0.0 1.4 1 1 0 1 1 1 0 Kinase-like APH PF01636.18 ETO24681.1 - 0.12 12.0 0.0 0.56 9.8 0.0 1.7 1 1 0 2 2 2 0 Phosphotransferase enzyme family Sulfate_transp PF00916.15 ETO24682.1 - 2e-15 56.5 0.8 2e-15 56.5 0.6 1.5 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 ETO24682.1 - 9.6e-09 34.7 0.6 9.6e-09 34.7 0.4 2.1 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif RhodobacterPufX PF11511.3 ETO24682.1 - 0.86 9.0 6.6 3.6 7.0 0.1 2.8 3 0 0 3 3 3 0 Intrinsic membrane protein PufX CcmD PF04995.9 ETO24682.1 - 1.4 8.7 5.9 0.62 9.8 1.8 2.1 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) MARVEL PF01284.18 ETO24682.1 - 4.2 7.1 14.2 3.8 7.3 8.6 1.8 1 1 1 2 2 2 0 Membrane-associating domain Transglut_i_TM PF14400.1 ETO24683.1 - 0.039 13.4 0.3 0.051 13.0 0.2 1.1 1 0 0 1 1 1 0 Inactive transglutaminase fused to 7 transmembrane helices FERM_N PF09379.5 ETO24685.1 - 0.078 13.0 1.1 0.23 11.5 0.7 1.8 1 1 0 1 1 1 0 FERM N-terminal domain DUF2207 PF09972.4 ETO24686.1 - 0.0019 16.8 1.2 0.0026 16.3 0.8 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF1649 PF07855.7 ETO24687.1 - 0.0021 17.7 0.6 0.0029 17.3 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) DUF912 PF06024.7 ETO24687.1 - 0.0057 16.6 1.8 0.0057 16.6 1.2 2.0 1 1 1 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) TMV_coat PF00721.16 ETO24687.1 - 0.097 12.6 0.1 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Virus coat protein (TMV like) Kinesin PF00225.18 ETO24689.1 - 5.2e-59 199.6 11.5 3.1e-47 160.9 2.9 2.2 2 0 0 2 2 2 2 Kinesin motor domain P53 PF00870.13 ETO24689.1 - 0.04 13.5 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 P53 DNA-binding domain CAP_GLY PF01302.20 ETO24690.1 - 1.5e-17 63.0 0.1 2.2e-17 62.5 0.1 1.2 1 0 0 1 1 1 1 CAP-Gly domain TPR_12 PF13424.1 ETO24693.1 - 1e-148 483.5 53.8 2.8e-21 75.2 0.1 8.9 8 1 0 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.1 ETO24693.1 - 3e-108 351.1 0.0 3.1e-09 36.4 0.0 16.1 15 1 1 16 16 16 15 Tetratricopeptide repeat TPR_1 PF00515.23 ETO24693.1 - 5e-106 342.4 117.0 7.3e-09 34.8 0.3 17.2 16 1 1 17 17 17 17 Tetratricopeptide repeat TPR_11 PF13414.1 ETO24693.1 - 3.6e-95 311.6 83.0 2.9e-16 58.8 2.4 11.2 5 2 4 11 11 11 10 TPR repeat TPR_2 PF07719.12 ETO24693.1 - 1.2e-90 290.3 87.6 6.9e-07 28.7 0.3 16.7 16 1 0 16 16 16 16 Tetratricopeptide repeat TPR_7 PF13176.1 ETO24693.1 - 1.3e-74 240.1 35.5 1e-05 24.9 0.0 16.0 16 0 0 16 16 16 15 Tetratricopeptide repeat TPR_8 PF13181.1 ETO24693.1 - 1.7e-66 215.0 124.7 9.2e-07 28.2 0.5 17.3 16 1 1 17 17 17 15 Tetratricopeptide repeat TPR_16 PF13432.1 ETO24693.1 - 5.6e-41 138.3 0.2 1.6e-05 25.4 0.0 10.5 8 3 3 11 11 11 7 Tetratricopeptide repeat TPR_14 PF13428.1 ETO24693.1 - 1.9e-37 124.2 0.0 0.65 10.7 0.0 15.9 16 0 0 16 16 16 6 Tetratricopeptide repeat TPR_6 PF13174.1 ETO24693.1 - 5.8e-31 104.8 35.1 0.071 13.6 0.0 15.8 16 0 0 16 16 15 7 Tetratricopeptide repeat TPR_17 PF13431.1 ETO24693.1 - 4e-24 82.7 52.8 0.048 13.8 0.6 16.1 14 3 0 14 14 14 10 Tetratricopeptide repeat Apc3 PF12895.2 ETO24693.1 - 7.5e-18 64.4 78.3 0.00019 21.5 5.2 10.0 3 2 9 12 12 12 11 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO24693.1 - 7.3e-16 58.2 21.0 0.13 12.6 0.1 9.3 6 2 5 11 11 10 6 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO24693.1 - 4.6e-14 51.3 23.2 0.071 12.3 0.0 13.2 14 0 0 14 14 14 2 SHNi-TPR MIT PF04212.13 ETO24693.1 - 1.9e-08 34.0 62.3 0.14 12.0 0.4 15.3 13 2 3 16 16 16 2 MIT (microtubule interacting and transport) domain PPR PF01535.15 ETO24693.1 - 7.4e-06 25.6 29.1 1 9.4 0.0 12.4 15 0 0 15 15 13 1 PPR repeat Sel1 PF08238.7 ETO24693.1 - 0.00022 21.7 40.4 8.8 7.1 0.3 12.5 14 0 0 14 14 13 0 Sel1 repeat DUF627 PF04781.7 ETO24693.1 - 0.0027 17.3 39.1 2.9 7.5 0.4 11.1 6 5 5 11 11 11 1 Protein of unknown function (DUF627) MMPL PF03176.10 ETO24693.1 - 1.8 7.2 3.1 2.8 6.5 2.1 1.2 1 0 0 1 1 1 0 MMPL family Kelch_1 PF01344.20 ETO24694.1 - 1.4e-07 30.9 6.8 0.005 16.3 0.9 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO24694.1 - 8.1e-07 28.9 7.1 0.041 14.0 0.4 4.9 4 1 1 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO24694.1 - 1.3e-06 28.0 0.9 0.034 13.8 0.0 4.1 4 1 1 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO24694.1 - 5.6e-05 22.7 2.7 0.0029 17.3 0.2 3.9 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 ETO24694.1 - 0.026 14.6 0.1 3.1 8.0 0.0 3.8 5 0 0 5 5 5 0 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO24694.1 - 0.13 12.2 8.0 30 4.7 1.6 5.1 6 0 0 6 6 6 0 Kelch motif Kelch_1 PF01344.20 ETO24695.1 - 5.5e-08 32.2 2.8 0.065 12.7 0.3 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO24695.1 - 1.4e-06 28.2 6.4 1 9.6 0.0 4.8 3 1 1 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO24695.1 - 1.3e-05 24.8 1.1 0.09 12.5 0.0 3.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO24695.1 - 0.096 12.6 1.7 1.7 8.6 0.0 3.6 4 0 0 4 4 4 0 Kelch motif ESR1_C PF12743.2 ETO24695.1 - 0.15 11.6 2.3 0.36 10.4 1.6 1.6 1 0 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal Kelch_2 PF07646.10 ETO24695.1 - 0.42 10.4 6.2 4.6 7.1 0.8 3.9 4 1 0 4 4 4 0 Kelch motif DUF791 PF05631.9 ETO24696.1 - 1.3e-25 89.8 0.7 2e-25 89.2 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 ETO24696.1 - 7.2e-05 21.6 0.3 7.2e-05 21.6 0.2 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_C54 PF03416.14 ETO24696.1 - 0.056 12.5 0.0 0.094 11.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C54 Kinesin-relat_1 PF12711.2 ETO24697.1 - 0.19 12.1 2.7 0.24 11.7 1.9 1.2 1 0 0 1 1 1 0 Kinesin motor WD40 PF00400.27 ETO24698.1 - 0.00028 20.6 0.7 0.00094 18.9 0.2 2.1 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF1049 PF06305.6 ETO24699.1 - 0.0041 16.5 0.2 0.012 15.0 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1049) PIG-P PF08510.7 ETO24699.1 - 0.024 14.2 0.3 0.098 12.2 0.0 2.2 3 0 0 3 3 3 0 PIG-P PNP_UDP_1 PF01048.15 ETO24700.1 - 2e-05 23.7 0.0 0.015 14.2 0.0 2.1 1 1 1 2 2 2 2 Phosphorylase superfamily AA_permease_2 PF13520.1 ETO24702.1 - 3.9e-45 154.1 40.7 4.8e-45 153.8 28.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETO24702.1 - 8.4e-35 120.0 37.1 1.1e-34 119.6 25.7 1.1 1 0 0 1 1 1 1 Amino acid permease TPR_12 PF13424.1 ETO24703.1 - 1.8e-32 111.1 12.9 5.9e-15 54.9 1.1 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO24703.1 - 4.9e-18 64.5 8.4 2.4e-10 39.9 0.5 3.4 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 ETO24703.1 - 1.2e-15 56.0 15.4 2.9e-05 23.6 0.2 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO24703.1 - 9.2e-14 50.8 0.0 0.048 13.6 0.0 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO24703.1 - 3.1e-12 45.5 24.1 2.6e-06 26.8 0.6 4.9 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO24703.1 - 2.5e-10 39.3 20.2 0.00025 20.6 0.7 5.0 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO24703.1 - 8.5e-07 29.4 0.4 0.00055 20.5 0.1 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO24703.1 - 1.4e-06 27.6 5.9 0.4 10.5 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO24703.1 - 0.00017 21.8 10.0 0.53 10.8 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO24703.1 - 0.0017 18.4 3.2 1 9.6 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_3 PF07720.7 ETO24703.1 - 0.0026 17.4 15.5 0.19 11.5 0.4 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO24703.1 - 0.0043 17.1 9.7 0.079 13.1 0.9 3.3 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 ETO24703.1 - 0.008 16.7 0.0 8.9 7.2 0.0 3.3 3 0 0 3 3 2 1 Tetratricopeptide repeat DUF2225 PF09986.4 ETO24703.1 - 0.008 15.6 5.8 0.081 12.3 3.4 2.6 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) Clathrin_H_link PF13838.1 ETO24705.1 - 0.0022 17.8 0.3 0.0048 16.7 0.0 1.7 2 0 0 2 2 2 1 Clathrin-H-link AAA_18 PF13238.1 ETO24705.1 - 0.019 15.2 0.0 0.021 15.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF4131 PF13567.1 ETO24706.1 - 0.00046 19.6 0.3 0.00053 19.4 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) Nramp PF01566.13 ETO24706.1 - 1.7 7.3 5.8 2.1 7.0 4.0 1.2 1 0 0 1 1 1 0 Natural resistance-associated macrophage protein DUF2762 PF10960.3 ETO24707.1 - 0.0016 18.0 0.8 0.018 14.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2762) DUF2681 PF10883.3 ETO24707.1 - 0.16 12.2 0.8 2.3 8.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF460 PF04312.8 ETO24708.1 - 0.017 14.6 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF460) Methyltrans_RNA PF04452.9 ETO24708.1 - 0.17 11.0 1.3 0.26 10.3 0.9 1.4 1 1 0 1 1 1 0 RNA methyltransferase MutS_V PF00488.16 ETO24709.1 - 9.8e-09 34.9 0.0 2.4e-08 33.6 0.0 1.6 1 1 0 1 1 1 1 MutS domain V MCRS_N PF13325.1 ETO24709.1 - 0.016 14.6 0.2 0.025 14.0 0.1 1.3 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein Ank PF00023.25 ETO24711.1 - 0.00013 21.6 0.0 0.0024 17.5 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 ETO24711.1 - 0.022 14.9 0.0 0.14 12.4 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO24711.1 - 0.083 13.1 0.0 0.53 10.6 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.1 ETO24711.1 - 0.1 13.1 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DUF2320 PF10082.4 ETO24711.1 - 0.11 11.1 0.4 0.15 10.7 0.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2320) SelP_N PF04592.9 ETO24711.1 - 0.86 8.9 6.8 1.6 8.0 4.7 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Peroxin-22 PF12827.2 ETO24712.1 - 0.0072 16.0 1.4 0.0072 16.0 1.0 3.8 4 1 0 4 4 4 1 Peroxisomal biogenesis protein family AAA_22 PF13401.1 ETO24712.1 - 0.05 13.7 0.2 0.53 10.4 0.0 2.8 3 1 0 3 3 3 0 AAA domain zf-TRAF PF02176.13 ETO24714.1 - 1.7e-05 25.1 2.8 1.7e-05 25.1 2.0 2.8 2 1 0 2 2 2 1 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 ETO24714.1 - 0.025 14.5 1.4 0.025 14.5 1.0 3.6 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO24714.1 - 0.051 13.4 1.3 0.051 13.4 0.9 3.3 2 2 1 3 3 3 0 Ring finger domain TPR_2 PF07719.12 ETO24715.1 - 1.5e-09 37.0 0.6 4.8e-09 35.4 0.4 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO24715.1 - 2e-09 36.6 1.7 3.3e-09 35.9 0.6 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO24715.1 - 2.3e-08 33.8 1.4 6.2e-08 32.4 0.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO24715.1 - 2.6e-07 29.9 1.3 8.4e-07 28.3 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO24715.1 - 3.2e-07 29.6 0.1 9.4e-07 28.1 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO24715.1 - 5.1e-07 29.2 0.2 1.3e-06 27.8 0.1 1.8 1 0 0 1 1 1 1 TPR repeat TPR_14 PF13428.1 ETO24715.1 - 0.0099 16.4 0.0 0.03 14.9 0.0 1.8 2 0 0 2 2 1 1 Tetratricopeptide repeat Sel1 PF08238.7 ETO24715.1 - 0.012 16.2 0.2 0.023 15.3 0.1 1.5 1 0 0 1 1 1 0 Sel1 repeat TPR_16 PF13432.1 ETO24715.1 - 0.014 16.0 0.0 0.026 15.2 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO24715.1 - 0.014 15.8 0.3 0.051 14.0 0.0 2.2 2 0 0 2 2 1 0 Tetratricopeptide repeat MIT PF04212.13 ETO24715.1 - 0.03 14.1 0.2 0.03 14.1 0.2 2.6 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 ETO24715.1 - 0.061 13.2 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat PseudoU_synth_2 PF00849.17 ETO24715.1 - 0.75 9.6 6.1 1.2 8.9 3.0 2.4 1 1 2 3 3 3 0 RNA pseudouridylate synthase GvpO PF05800.6 ETO24715.1 - 0.87 9.5 6.4 0.11 12.3 0.7 2.2 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpO Neur_chan_memb PF02932.11 ETO24715.1 - 7.6 6.3 9.5 2.1 8.1 4.3 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region TPR_12 PF13424.1 ETO24716.1 - 5.6e-44 147.9 0.6 3.4e-16 58.9 0.0 4.3 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO24716.1 - 4e-24 84.0 7.6 3e-10 39.5 0.2 4.5 2 1 4 6 6 6 6 TPR repeat TPR_8 PF13181.1 ETO24716.1 - 6e-23 78.8 20.8 0.00013 21.5 0.4 6.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETO24716.1 - 3e-22 76.7 6.5 0.00034 20.3 0.1 6.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO24716.1 - 1.2e-17 62.6 14.4 0.00042 19.8 0.2 6.6 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO24716.1 - 9e-15 53.2 0.2 0.0033 17.1 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO24716.1 - 1.9e-13 49.8 0.0 0.053 13.4 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat Peptidase_C14 PF00656.17 ETO24716.1 - 2e-10 40.8 0.3 4.9e-10 39.5 0.2 1.7 1 0 0 1 1 1 1 Caspase domain TPR_17 PF13431.1 ETO24716.1 - 1.2e-09 37.6 1.4 1.5 9.2 0.0 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO24716.1 - 1.2e-08 34.7 1.6 0.66 10.5 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO24716.1 - 5.5e-06 26.4 0.3 0.0024 17.9 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 ETO24716.1 - 2.5e-05 24.4 0.0 26 5.8 0.0 4.9 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETO24716.1 - 3e-05 24.2 0.3 0.18 12.1 0.0 4.2 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO24716.1 - 7.8e-05 23.2 0.0 0.075 13.7 0.0 3.7 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_21 PF09976.4 ETO24716.1 - 0.00014 21.8 0.2 0.14 12.0 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_3 PF07720.7 ETO24716.1 - 0.56 10.0 7.4 0.22 11.3 0.4 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat WD40 PF00400.27 ETO24717.1 - 1.1e-35 120.1 10.3 1.6e-12 46.7 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat UBA PF00627.26 ETO24719.1 - 2.5e-05 23.9 0.1 7.3e-05 22.4 0.1 1.8 2 0 0 2 2 2 1 UBA/TS-N domain Cag12 PF13117.1 ETO24720.1 - 0.27 11.1 5.0 0.096 12.6 1.0 2.1 2 0 0 2 2 2 0 Cag pathogenicity island protein Cag12 FliJ PF02050.11 ETO24721.1 - 0.0035 17.3 2.9 0.0041 17.1 1.7 1.4 1 1 0 1 1 1 1 Flagellar FliJ protein Hydrophobin PF01185.13 ETO24721.1 - 0.069 13.6 0.5 0.12 12.8 0.3 1.3 1 0 0 1 1 1 0 Fungal hydrophobin DivIC PF04977.10 ETO24721.1 - 0.1 12.1 0.5 0.2 11.1 0.3 1.5 1 0 0 1 1 1 0 Septum formation initiator ETRAMP PF09716.5 ETO24721.1 - 0.12 12.3 1.5 0.21 11.5 1.0 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) RPA_interact_M PF14767.1 ETO24721.1 - 0.22 12.3 2.8 0.35 11.6 1.9 1.4 1 0 0 1 1 1 0 Replication protein A interacting middle PAH PF02671.16 ETO24721.1 - 1.8 8.2 6.6 1.3 8.7 2.9 2.3 2 1 1 3 3 3 0 Paired amphipathic helix repeat Ribosomal_S7e PF01251.13 ETO24722.1 - 0.02 14.3 1.6 0.02 14.3 1.1 2.0 2 0 0 2 2 2 0 Ribosomal protein S7e FlxA PF14282.1 ETO24722.1 - 0.048 13.6 15.7 0.63 10.0 3.7 2.2 2 0 0 2 2 2 0 FlxA-like protein Filament PF00038.16 ETO24722.1 - 0.097 12.1 17.0 3.7 6.9 11.7 2.1 1 1 1 2 2 2 0 Intermediate filament protein TraF_2 PF13729.1 ETO24722.1 - 0.2 10.4 1.8 0.55 8.9 0.4 2.3 2 1 0 2 2 2 0 F plasmid transfer operon, TraF, protein Vir_act_alpha_C PF10400.4 ETO24722.1 - 0.23 11.8 5.8 3.9 7.9 1.3 2.6 2 1 0 2 2 2 0 Virulence activator alpha C-term Exonuc_VII_L PF02601.10 ETO24722.1 - 0.28 10.3 10.8 0.37 9.9 7.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Paramyx_P_V_C PF03210.8 ETO24722.1 - 0.39 10.5 4.7 3.2 7.6 0.4 2.1 2 0 0 2 2 2 0 Paramyxovirus P/V phosphoprotein C-terminal DUF4168 PF13767.1 ETO24722.1 - 0.64 10.6 5.8 0.57 10.8 1.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4168) HemX PF04375.9 ETO24722.1 - 0.73 8.3 10.3 0.36 9.3 2.8 2.0 2 0 0 2 2 2 0 HemX tRNA-synt_1c PF00749.16 ETO24722.1 - 0.75 8.3 5.8 0.42 9.2 2.8 1.4 1 1 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain DivIC PF04977.10 ETO24722.1 - 0.8 9.2 20.9 0.68 9.4 2.3 3.4 1 1 2 3 3 3 0 Septum formation initiator DUF3373 PF11853.3 ETO24722.1 - 0.83 8.1 7.9 0.25 9.8 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) Mod_r PF07200.8 ETO24722.1 - 0.86 9.5 21.4 0.15 11.9 7.3 2.1 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein tRNA-synt_His PF13393.1 ETO24722.1 - 0.98 8.4 9.9 0.47 9.4 3.3 2.1 1 1 1 2 2 2 0 Histidyl-tRNA synthetase DUF3166 PF11365.3 ETO24722.1 - 0.99 9.9 9.7 0.16 12.4 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) DUF948 PF06103.6 ETO24722.1 - 1.7 8.5 5.0 15 5.5 0.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.7 ETO24722.1 - 1.7 8.4 6.2 8.8 6.1 0.4 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc24 PF08286.6 ETO24722.1 - 2 8.1 15.5 5.5 6.7 4.5 2.5 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 RPN7 PF10602.4 ETO24722.1 - 2.1 7.7 7.2 1.4 8.2 0.5 2.2 2 0 0 2 2 2 0 26S proteasome subunit RPN7 Prefoldin PF02996.12 ETO24722.1 - 2.7 7.6 17.5 1.4 8.6 2.9 2.9 2 1 1 3 3 3 0 Prefoldin subunit DUF1640 PF07798.6 ETO24722.1 - 2.8 7.9 16.0 16 5.5 11.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF972 PF06156.8 ETO24722.1 - 3.4 8.0 17.9 2 8.8 6.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF3782 PF12644.2 ETO24722.1 - 4.5 7.1 6.8 1.1 9.1 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) Allexi_40kDa PF05549.6 ETO24722.1 - 5.4 6.2 10.7 3 7.0 2.0 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF1953 PF09196.5 ETO24723.1 - 0.085 12.5 0.6 15 5.3 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1953) Pkinase PF00069.20 ETO24724.1 - 3.9e-18 65.5 0.0 1.8e-17 63.3 0.0 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO24724.1 - 2.5e-06 26.7 0.0 0.052 12.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Corona_nucleoca PF00937.13 ETO24725.1 - 0.35 9.7 6.6 0.38 9.6 4.6 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein eIF_4EBP PF05456.6 ETO24725.1 - 0.38 10.4 4.1 0.44 10.2 2.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Peptidase_S49_N PF08496.5 ETO24725.1 - 9.5 5.9 8.0 9.8 5.9 5.5 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PPR_2 PF13041.1 ETO24726.1 - 4.9e-12 45.6 4.3 6.7e-07 29.1 0.1 4.5 4 1 1 5 5 5 3 PPR repeat family PPR PF01535.15 ETO24726.1 - 8.6e-12 44.2 5.1 0.0065 16.3 0.0 5.2 5 0 0 5 5 5 4 PPR repeat PPR_3 PF13812.1 ETO24726.1 - 1.1e-11 43.9 0.2 0.012 15.7 0.0 4.7 4 0 0 4 4 4 3 Pentatricopeptide repeat domain PPR_1 PF12854.2 ETO24726.1 - 0.00023 20.5 0.0 0.029 13.8 0.0 2.9 2 0 0 2 2 2 1 PPR repeat ATP13 PF12921.2 ETO24726.1 - 0.017 14.4 0.2 0.045 13.0 0.1 1.8 1 0 0 1 1 1 0 Mitochondrial ATPase expression BRF1 PF07741.8 ETO24726.1 - 1.2 9.4 6.2 3.5 7.8 4.3 1.8 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Spc97_Spc98 PF04130.8 ETO24729.1 - 5.4e-24 84.4 10.2 6.4e-24 84.1 7.1 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Spc97_Spc98 PF04130.8 ETO24730.1 - 4.5e-20 71.4 0.6 6.7e-20 70.9 0.4 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF3504 PF12012.3 ETO24730.1 - 0.036 13.8 0.7 0.074 12.8 0.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3504) WD40 PF00400.27 ETO24732.1 - 6.6e-07 28.9 6.2 0.0038 17.0 0.3 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat RabGAP-TBC PF00566.13 ETO24733.1 - 2.1e-24 86.1 2.1 2.1e-24 86.1 1.4 5.0 4 1 0 4 4 4 2 Rab-GTPase-TBC domain Ank_2 PF12796.2 ETO24735.1 - 2.8e-15 56.4 1.8 3.9e-06 27.0 0.1 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO24735.1 - 4.9e-10 39.6 1.1 0.0015 19.0 0.0 4.3 2 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 ETO24735.1 - 1.6e-07 30.7 2.6 0.00044 19.9 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 ETO24735.1 - 3.3e-07 29.9 4.4 0.0012 18.9 0.1 5.1 5 1 1 6 6 6 1 Ankyrin repeat Ank_5 PF13857.1 ETO24735.1 - 3e-06 27.2 1.2 0.56 10.5 0.2 4.2 3 2 2 5 5 5 3 Ankyrin repeats (many copies) DUF3439 PF11921.3 ETO24736.1 - 1.9 8.2 8.9 5.8 6.6 6.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Glyco_transf_18 PF15024.1 ETO24737.1 - 2e-11 42.9 0.0 3.6e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 18 TMEM138 PF14935.1 ETO24737.1 - 0.011 16.0 0.7 1 9.6 0.1 2.5 2 0 0 2 2 2 0 Transmembrane protein 138 Psu PF07455.6 ETO24737.1 - 0.023 14.2 0.1 0.11 11.9 0.0 2.0 2 0 0 2 2 2 0 Phage polarity suppression protein (Psu) GTP_EFTU PF00009.22 ETO24738.1 - 1.9e-27 95.9 0.1 3.4e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 ETO24738.1 - 0.00025 21.1 0.0 0.00072 19.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain DUF258 PF03193.11 ETO24738.1 - 0.0013 17.9 0.1 0.0029 16.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU_D2 PF03144.20 ETO24738.1 - 0.0019 18.2 0.1 0.036 14.1 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu domain 2 ATP_bind_1 PF03029.12 ETO24738.1 - 0.0045 16.5 0.2 0.22 11.0 0.0 3.0 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 ETO24738.1 - 0.0079 16.1 0.0 0.03 14.2 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 ETO24738.1 - 0.043 13.3 0.0 0.33 10.4 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Pkinase PF00069.20 ETO24739.1 - 3.1e-21 75.6 1.8 2.1e-19 69.7 1.3 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO24739.1 - 4.3e-13 48.9 0.7 9e-12 44.6 0.5 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase OST3_OST6 PF04756.8 ETO24739.1 - 0.15 11.5 0.6 1 8.8 0.1 2.0 2 0 0 2 2 2 0 OST3 / OST6 family Pkinase PF00069.20 ETO24741.1 - 1.3e-38 132.7 1.2 1.8e-38 132.1 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO24741.1 - 2.6e-10 39.8 1.7 3.8e-10 39.2 0.1 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase VID27 PF08553.5 ETO24741.1 - 0.023 12.9 12.5 0.031 12.5 8.7 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein NOA36 PF06524.7 ETO24741.1 - 0.11 11.6 7.8 0.15 11.2 5.4 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2500 PF10694.4 ETO24741.1 - 0.15 12.1 2.9 0.098 12.6 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2500) HXXSHH PF07586.6 ETO24743.1 - 0.012 14.6 0.7 0.021 13.7 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) AIF_C PF14721.1 ETO24743.1 - 5.2 7.3 8.7 0.22 11.7 1.3 2.1 2 1 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Orbi_VP5 PF00901.12 ETO24743.1 - 6.8 4.7 10.3 0.044 11.9 0.2 1.9 2 0 0 2 2 2 0 Orbivirus outer capsid protein VP5 HgmA PF04209.8 ETO24744.1 - 9.8e-69 231.7 0.0 1.2e-68 231.5 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Sulfate_tra_GLY PF13792.1 ETO24745.1 - 2.1e-12 46.4 12.2 1.9e-06 27.4 2.3 3.5 3 0 0 3 3 3 2 Sulfate transporter N-terminal domain with GLY motif Sulfate_transp PF00916.15 ETO24745.1 - 1.8e-08 33.7 3.1 1.8e-08 33.7 2.1 2.4 2 1 1 3 3 3 2 Sulfate transporter family DUF2633 PF11119.3 ETO24745.1 - 0.031 13.9 0.1 0.097 12.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) CarbpepA_inh PF02977.10 ETO24745.1 - 0.13 11.8 0.1 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase A inhibitor Adeno_E3_14_5 PF04834.7 ETO24745.1 - 3.3 8.1 6.3 12 6.4 0.1 3.5 2 1 1 3 3 3 0 Early E3 14.5 kDa protein WD40 PF00400.27 ETO24746.1 - 2.1e-10 40.0 1.0 0.0019 18.0 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat Reo_sigmaC PF04582.7 ETO24746.1 - 0.53 9.4 5.7 0.3 10.2 0.1 2.9 2 1 2 4 4 4 0 Reovirus sigma C capsid protein Menin PF05053.8 ETO24747.1 - 0.03 12.4 7.0 0.046 11.8 4.9 1.2 1 0 0 1 1 1 0 Menin GOLD_2 PF13897.1 ETO24747.1 - 2.3 8.4 6.2 2.7 8.2 0.8 2.4 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Sigma70_ner PF04546.8 ETO24747.1 - 5.4 6.5 12.1 1.6 8.3 1.6 3.1 3 0 0 3 3 3 0 Sigma-70, non-essential region SieB PF14163.1 ETO24748.1 - 0.99 8.9 3.4 0.41 10.2 0.4 1.7 2 0 0 2 2 2 0 Superinfection exclusion protein B Tom22 PF04281.8 ETO24749.1 - 1.4 8.4 6.1 0.61 9.6 2.6 1.6 1 1 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 START PF01852.14 ETO24750.1 - 0.02 14.2 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 START domain Hist_deacetyl PF00850.14 ETO24751.1 - 6.6e-62 209.5 0.2 8.2e-62 209.2 0.1 1.0 1 0 0 1 1 1 1 Histone deacetylase domain VID27 PF08553.5 ETO24752.1 - 0.011 14.0 0.0 0.013 13.7 0.0 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein TRP PF06011.7 ETO24753.1 - 1.9e-07 30.0 5.6 2e-07 29.9 3.9 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel PRA1 PF03208.14 ETO24753.1 - 0.0039 16.5 3.0 0.0057 16.0 2.1 1.3 1 0 0 1 1 1 1 PRA1 family protein Claudin_2 PF13903.1 ETO24753.1 - 0.025 14.2 3.0 0.035 13.7 2.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF3404 PF11884.3 ETO24753.1 - 0.053 12.4 1.8 0.074 11.9 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) DUF1211 PF06736.6 ETO24753.1 - 0.067 13.3 0.2 0.067 13.3 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1211) P12 PF12669.2 ETO24753.1 - 0.3 11.3 1.4 0.38 10.9 0.2 1.8 1 1 1 2 2 2 0 Virus attachment protein p12 family MDFI PF15316.1 ETO24753.1 - 0.83 9.6 3.2 7.5 6.5 0.6 2.1 2 0 0 2 2 2 0 MyoD family inhibitor Peptidase_S49_N PF08496.5 ETO24753.1 - 0.94 9.2 4.3 0.39 10.5 0.4 1.9 1 1 1 2 2 2 0 Peptidase family S49 N-terminal EphA2_TM PF14575.1 ETO24753.1 - 1.1 9.6 4.6 0.66 10.4 0.2 2.5 1 1 2 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain ATS PF15445.1 ETO24753.1 - 2.1 7.3 5.3 11 5.0 0.1 2.0 2 0 0 2 2 2 0 acidic terminal segments, variant surface antigen of PfEMP1 WBP-1 PF11669.3 ETO24753.1 - 2.6 8.1 6.9 2.7 8.1 3.8 1.9 1 1 0 1 1 1 0 WW domain-binding protein 1 FH2 PF02181.18 ETO24754.1 - 3.4e-66 223.6 18.9 3.4e-66 223.6 13.1 2.1 1 1 1 2 2 2 1 Formin Homology 2 Domain DUF2951 PF11166.3 ETO24754.1 - 2.7 7.9 17.0 2 8.3 3.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2951) DUF1510 PF07423.6 ETO24755.1 - 2.6e-05 23.7 2.4 4.4e-05 22.9 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) CIMR PF00878.13 ETO24755.1 - 0.0013 18.4 6.0 0.0085 15.8 0.3 2.4 2 0 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat Protocadherin PF08374.6 ETO24755.1 - 0.0025 17.4 0.1 0.0044 16.6 0.1 1.3 1 0 0 1 1 1 1 Protocadherin EGF_2 PF07974.8 ETO24755.1 - 0.0034 17.5 4.2 0.0034 17.5 2.9 3.8 4 1 0 4 4 4 1 EGF-like domain Endomucin PF07010.7 ETO24755.1 - 0.026 13.8 1.9 0.055 12.8 1.3 1.4 1 0 0 1 1 1 0 Endomucin Col_cuticle_N PF01484.12 ETO24755.1 - 0.1 12.3 1.6 0.23 11.1 1.1 1.6 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain Rifin_STEVOR PF02009.11 ETO24755.1 - 0.17 11.4 0.0 0.17 11.4 0.0 1.6 2 0 0 2 2 2 0 Rifin/stevor family DUF912 PF06024.7 ETO24755.1 - 0.27 11.2 5.0 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Sigma70_ner PF04546.8 ETO24757.1 - 0.0028 17.2 6.9 0.0039 16.8 4.7 1.1 1 0 0 1 1 1 1 Sigma-70, non-essential region CDC45 PF02724.9 ETO24757.1 - 0.0046 15.0 5.4 0.0055 14.7 3.8 1.2 1 0 0 1 1 1 1 CDC45-like protein FLO_LFY PF01698.11 ETO24757.1 - 0.022 13.5 0.4 0.028 13.2 0.3 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein NOA36 PF06524.7 ETO24757.1 - 2.6 7.2 15.5 4 6.6 10.7 1.3 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.7 ETO24757.1 - 4.5 6.4 17.2 5.9 6.0 12.0 1.1 1 0 0 1 1 1 0 SDA1 CobT PF06213.7 ETO24757.1 - 5.2 6.1 15.0 7.2 5.6 10.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 ETO24757.1 - 8.7 4.1 14.7 11 3.7 10.2 1.1 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.6 ETO24757.1 - 8.9 4.0 10.0 13 3.5 6.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2457 PF10446.4 ETO24757.1 - 9.7 4.7 25.2 14 4.2 17.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Dyp_perox PF04261.7 ETO24758.1 - 2.6e-06 26.3 0.2 1.7e-05 23.7 0.0 2.3 2 1 1 3 3 3 1 Dyp-type peroxidase family Peptidase_C21 PF05381.7 ETO24758.1 - 0.00085 19.3 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 Tymovirus endopeptidase Cnd1 PF12717.2 ETO24759.1 - 2.2e-54 183.9 9.5 3.6e-53 180.0 3.7 3.1 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 ETO24759.1 - 2.6e-06 26.0 0.6 4.3e-06 25.3 0.4 1.4 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 ETO24759.1 - 2.3e-05 24.5 0.2 6.8e-05 23.0 0.1 1.8 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.17 ETO24759.1 - 4.8e-05 23.0 0.0 0.73 10.0 0.0 2.9 2 0 0 2 2 2 2 HEAT repeat SNARE_assoc PF09335.6 ETO24760.1 - 6.5e-05 23.1 1.0 6.5e-05 23.1 0.7 1.9 3 0 0 3 3 3 1 SNARE associated Golgi protein CAP_N PF01213.14 ETO24761.1 - 0.00011 21.5 0.0 0.00015 21.1 0.0 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal NACHT PF05729.7 ETO24762.1 - 8e-09 35.3 0.0 1.7e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO24762.1 - 2.9e-06 27.6 2.8 4.9e-06 26.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ETO24762.1 - 0.00012 22.8 0.6 0.0014 19.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 ETO24762.1 - 0.00021 21.4 0.0 0.00066 19.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 ETO24762.1 - 0.039 13.5 0.0 0.15 11.7 0.0 2.0 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 ETO24762.1 - 0.043 14.1 0.1 0.25 11.6 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.1 ETO24762.1 - 0.066 13.0 0.0 1.3 8.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 ETO24762.1 - 0.12 11.9 0.0 0.37 10.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain WD40 PF00400.27 ETO24763.1 - 2.5e-186 597.7 41.2 2.5e-14 52.5 0.1 16.1 16 0 0 16 16 16 16 WD domain, G-beta repeat Nup160 PF11715.3 ETO24763.1 - 4.9e-19 67.8 26.5 0.08 11.0 0.0 12.7 1 1 13 14 14 14 9 Nucleoporin Nup120/160 DUF1258 PF06869.7 ETO24763.1 - 1.9e-12 46.8 4.5 0.21 10.6 0.1 7.9 4 2 2 8 8 8 4 Protein of unknown function (DUF1258) SGL PF08450.7 ETO24763.1 - 1.1e-11 44.6 3.4 0.15 11.4 0.0 6.7 2 2 3 6 6 6 3 SMP-30/Gluconolaconase/LRE-like region PD40 PF07676.7 ETO24763.1 - 2.9e-09 36.3 27.7 5.4 6.7 0.1 11.1 12 0 0 12 12 12 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO24763.1 - 2.1e-08 32.8 11.1 0.19 9.9 0.1 6.7 3 2 5 8 8 8 5 Cytochrome D1 heme domain Str_synth PF03088.11 ETO24763.1 - 3e-08 33.5 1.4 2.5 8.1 0.0 8.8 6 4 5 11 11 11 1 Strictosidine synthase Resistin PF06954.6 ETO24763.1 - 0.0011 19.1 1.0 10 6.5 0.0 6.0 6 2 1 8 8 6 1 Resistin FmdE PF02663.9 ETO24763.1 - 0.0026 17.6 0.4 4.3 7.2 0.0 3.6 3 1 0 4 4 4 1 FmdE, Molybdenum formylmethanofuran dehydrogenase operon NYD-SP28_assoc PF14775.1 ETO24763.1 - 0.0072 15.9 16.7 56 3.5 0.0 10.4 15 0 0 15 15 15 0 Sperm tail C-terminal domain F420_ligase PF01996.11 ETO24763.1 - 0.022 13.8 0.1 0.78 8.7 0.0 3.3 3 2 0 3 3 3 0 F420-0:Gamma-glutamyl ligase Corona_NS8 PF12093.3 ETO24763.1 - 0.062 13.6 0.0 1.2e+02 3.0 0.0 4.5 4 1 1 5 5 4 0 Coronavirus NS8 protein Peptidase_C69 PF03577.10 ETO24763.1 - 0.19 10.5 7.5 13 4.5 0.0 5.9 6 1 1 7 7 7 0 Peptidase family C69 WD40 PF00400.27 ETO24764.1 - 6.7e-76 247.7 11.5 3e-12 45.9 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO24764.1 - 3.1e-09 35.5 3.5 0.00028 19.1 0.1 4.1 2 1 1 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO24764.1 - 7.7e-06 24.9 13.1 1.2 7.8 1.4 5.8 1 1 4 6 6 6 2 Nup133 N terminal like PQQ_2 PF13360.1 ETO24764.1 - 0.0002 20.9 0.2 0.00058 19.3 0.2 1.9 1 1 0 1 1 1 1 PQQ-like domain DUF1258 PF06869.7 ETO24764.1 - 0.00032 19.8 0.4 0.068 12.2 0.0 3.0 1 1 1 3 3 3 2 Protein of unknown function (DUF1258) Resistin PF06954.6 ETO24764.1 - 0.0012 19.0 0.1 16 5.8 0.0 4.1 3 1 1 4 4 4 1 Resistin PD40 PF07676.7 ETO24764.1 - 0.011 15.4 1.8 13 5.6 0.0 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat G-alpha PF00503.15 ETO24765.1 - 1.4e-57 195.1 32.1 9.2e-56 189.1 17.5 2.7 2 1 0 2 2 2 2 G-protein alpha subunit Arf PF00025.16 ETO24765.1 - 3.4e-07 29.6 2.5 4.2e-07 29.3 0.2 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO24765.1 - 0.00091 18.7 1.3 0.006 16.0 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain PTS-HPr PF00381.14 ETO24765.1 - 0.042 13.7 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 PTS HPr component phosphorylation site AAA_22 PF13401.1 ETO24765.1 - 0.058 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 ETO24765.1 - 0.36 11.3 5.1 2.2 8.7 0.2 3.3 3 0 0 3 3 3 0 Miro-like protein GCFC PF07842.7 ETO24767.1 - 1e-09 38.1 1.5 0.00037 19.9 0.0 2.8 1 1 1 2 2 2 2 GC-rich sequence DNA-binding factor-like protein FlaC_arch PF05377.6 ETO24767.1 - 0.69 9.8 4.4 23 4.9 0.7 2.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Pox_Ag35 PF03286.9 ETO24768.1 - 0.31 10.5 20.6 0.12 11.8 5.6 2.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF1510 PF07423.6 ETO24768.1 - 4.2 6.6 28.0 2.9 7.2 8.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) HSP70 PF00012.15 ETO24769.1 - 0.021 12.7 0.0 1.4 6.7 0.0 2.2 2 0 0 2 2 2 0 Hsp70 protein WD40 PF00400.27 ETO24770.1 - 1.7e-40 135.4 22.7 1.3e-09 37.5 0.7 6.5 5 1 1 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO24770.1 - 4.8e-07 28.3 0.5 0.27 9.3 0.0 4.3 3 1 1 4 4 4 3 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO24770.1 - 1.4e-06 28.5 2.4 1.4e-06 28.5 1.7 2.7 2 0 0 2 2 2 1 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 ETO24770.1 - 3 7.9 11.4 0.41 10.7 2.1 3.9 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Prothymosin PF03247.9 ETO24771.1 - 0.016 15.3 24.1 0.016 15.3 16.7 3.3 2 1 0 2 2 2 0 Prothymosin/parathymosin family PWWP PF00855.12 ETO24772.1 - 6.1e-08 32.7 0.1 2.9e-06 27.3 0.0 2.9 2 1 0 2 2 2 1 PWWP domain WD40 PF00400.27 ETO24774.1 - 1.5e-78 256.1 24.9 1.8e-13 49.7 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat AA_permease PF00324.16 ETO24774.1 - 9.1e-06 24.2 0.9 1.6e-05 23.4 0.6 1.4 1 0 0 1 1 1 1 Amino acid permease Proteasome_A_N PF10584.4 ETO24774.1 - 0.00014 21.0 4.8 17 4.8 0.0 5.7 5 0 0 5 5 5 2 Proteasome subunit A N-terminal signature Cytochrom_D1 PF02239.11 ETO24774.1 - 0.00068 18.0 0.5 1.9 6.7 0.0 3.2 2 1 2 4 4 4 3 Cytochrome D1 heme domain HERV-K_env_2 PF13804.1 ETO24774.1 - 0.0051 16.3 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 Retro-transcribing viruses envelope glycoprotein PD40 PF07676.7 ETO24774.1 - 0.21 11.2 9.1 9.1 6.0 0.1 5.7 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO24774.1 - 0.22 11.8 1.1 88 3.4 0.0 4.2 2 2 3 5 5 5 0 Resistin AA_permease PF00324.16 ETO24775.1 - 1.3e-23 83.1 8.8 1.9e-23 82.6 6.1 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETO24775.1 - 1.2e-12 47.1 8.7 1.4e-12 46.8 6.1 1.1 1 0 0 1 1 1 1 Amino acid permease Ipi1_N PF12333.3 ETO24778.1 - 0.21 11.5 2.2 0.31 11.0 0.5 2.1 1 1 1 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation P16-Arc PF04699.9 ETO24778.1 - 7 6.6 7.3 4.2 7.3 0.7 2.2 2 0 0 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) PPR_2 PF13041.1 ETO24780.1 - 0.021 14.8 2.0 0.37 10.8 0.3 3.2 2 1 1 3 3 3 0 PPR repeat family PPR_3 PF13812.1 ETO24780.1 - 0.09 13.1 0.1 0.45 10.9 0.0 2.3 1 0 0 1 1 1 0 Pentatricopeptide repeat domain PPR PF01535.15 ETO24780.1 - 0.1 12.6 0.1 0.56 10.2 0.0 2.3 2 0 0 2 2 2 0 PPR repeat WD40 PF00400.27 ETO24781.1 - 8.5e-48 158.6 10.4 7.1e-14 51.0 0.1 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO24781.1 - 1.2e-08 34.9 0.0 0.0013 18.4 0.0 3.5 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO24781.1 - 5.4e-07 28.2 0.1 0.00049 18.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.7 ETO24781.1 - 1.5e-05 24.4 6.5 0.53 9.9 0.0 5.6 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO24781.1 - 0.00027 19.8 0.2 0.22 10.1 0.0 2.8 2 1 1 3 3 3 2 Nup133 N terminal like Nbas_N PF15492.1 ETO24781.1 - 0.0012 17.9 0.1 0.56 9.2 0.0 3.1 2 1 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal TFIIIC_delta PF12657.2 ETO24781.1 - 0.0039 16.9 0.2 0.13 11.9 0.1 2.6 1 1 1 2 2 2 1 Transcription factor IIIC subunit delta N-term PQQ_2 PF13360.1 ETO24781.1 - 0.011 15.2 0.0 0.3 10.5 0.0 2.4 1 1 1 2 2 2 0 PQQ-like domain Nup160 PF11715.3 ETO24781.1 - 0.014 13.5 0.0 0.053 11.6 0.0 1.9 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 ETO24781.1 - 0.018 13.8 0.0 0.31 9.7 0.0 2.0 1 1 1 2 2 2 0 Coatomer WD associated region DHFR_2 PF06442.6 ETO24781.1 - 0.11 12.1 0.0 3.6 7.2 0.0 2.7 3 0 0 3 3 3 0 R67 dihydrofolate reductase Proteasome_A_N PF10584.4 ETO24781.1 - 4.1 6.8 15.2 6.5 6.1 0.0 4.7 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature SURF1 PF02104.10 ETO24782.1 - 0.00039 20.3 0.0 0.00054 19.8 0.0 1.2 1 0 0 1 1 1 1 SURF1 family WD40 PF00400.27 ETO24783.1 - 6e-39 130.5 1.6 4.1e-11 42.3 0.0 7.5 8 0 0 8 8 8 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO24783.1 - 0.00024 19.9 5.8 0.18 10.4 0.1 3.1 1 1 1 3 3 3 2 Nup133 N terminal like Kelch_4 PF13418.1 ETO24783.1 - 0.00081 19.1 0.2 0.0081 15.9 0.0 2.8 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO24783.1 - 0.0012 18.2 5.2 0.0073 15.8 0.2 3.6 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 ETO24783.1 - 0.0032 17.5 4.4 1 9.6 0.1 3.9 3 1 1 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO24783.1 - 0.012 15.5 0.4 48 4.0 0.1 4.4 4 0 0 4 4 4 0 Kelch motif Cytochrom_D1 PF02239.11 ETO24783.1 - 0.046 12.0 0.3 0.33 9.2 0.1 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain Kelch_3 PF13415.1 ETO24783.1 - 0.058 13.5 0.0 0.25 11.5 0.0 2.1 1 0 0 1 1 1 0 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO24783.1 - 0.16 11.8 0.2 0.16 11.8 0.1 4.2 4 1 0 4 4 4 0 Kelch motif PD40 PF07676.7 ETO24783.1 - 0.24 11.1 1.0 33 4.2 0.0 3.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 ETO24784.1 - 2.3e-50 166.7 11.1 2.6e-12 46.0 0.0 7.3 7 1 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO24784.1 - 7e-11 42.1 0.1 0.01 15.5 0.0 3.7 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO24784.1 - 8.1e-06 24.2 2.3 0.023 12.8 0.1 4.0 1 1 0 2 2 2 2 Nucleoporin Nup120/160 PD40 PF07676.7 ETO24784.1 - 0.00014 21.4 1.2 7.1 6.4 0.0 4.3 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO24784.1 - 0.00014 20.3 0.8 0.58 8.3 0.1 3.3 2 1 0 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO24784.1 - 0.00098 17.9 12.2 0.39 9.4 0.1 4.7 2 2 2 4 4 4 2 Nup133 N terminal like Proteasome_A_N PF10584.4 ETO24784.1 - 0.11 11.8 5.1 18 4.7 0.0 4.9 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Hydrolase PF00702.21 ETO24785.1 - 2.1e-13 51.1 0.0 6.5e-12 46.3 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETO24785.1 - 3e-11 43.8 0.3 1.1e-10 42.0 0.2 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETO24785.1 - 8.2e-10 38.5 0.1 2.6e-09 36.8 0.1 2.0 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 ETO24785.1 - 3.2e-09 36.1 0.0 7.1e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.7 ETO24785.1 - 0.2 11.1 4.6 0.041 13.4 0.3 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Cnd1_N PF12922.2 ETO24786.1 - 0.0056 16.3 1.1 0.0075 15.9 0.8 1.2 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Endonuclease_1 PF04231.8 ETO24786.1 - 0.04 13.7 3.8 0.052 13.3 2.6 1.2 1 1 0 1 1 1 0 Endonuclease I DDHD PF02862.12 ETO24786.1 - 0.11 12.2 1.9 0.13 12.0 1.3 1.0 1 0 0 1 1 1 0 DDHD domain DUF3464 PF11947.3 ETO24786.1 - 0.45 9.9 2.9 0.53 9.7 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) TPR_11 PF13414.1 ETO24787.1 - 4.5e-15 55.0 7.1 3e-07 29.9 0.1 4.1 1 1 1 4 4 4 3 TPR repeat TPR_2 PF07719.12 ETO24787.1 - 8.1e-13 47.2 9.9 0.045 13.6 0.0 6.4 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO24787.1 - 4.3e-12 45.2 2.4 0.064 13.4 0.0 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO24787.1 - 3.5e-08 32.7 6.6 0.097 12.3 0.0 6.3 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO24787.1 - 9.5e-08 32.5 0.7 0.03 15.0 0.0 3.8 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO24787.1 - 1.8e-07 31.1 1.0 1.3 9.8 0.0 5.2 3 3 2 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO24787.1 - 2.9e-07 30.3 2.5 0.0001 22.1 0.1 4.4 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO24787.1 - 2e-06 27.1 0.4 0.93 9.4 0.0 5.1 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO24787.1 - 3.4e-06 27.2 1.9 0.11 12.8 0.0 4.1 3 3 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO24787.1 - 4.6e-05 23.5 0.1 4 8.0 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETO24787.1 - 0.0034 17.2 0.5 2.1 8.2 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETO24787.1 - 0.048 13.6 0.1 72 3.5 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat CDC45 PF02724.9 ETO24787.1 - 0.19 9.6 3.5 0.3 9.0 2.5 1.2 1 0 0 1 1 1 0 CDC45-like protein TPR_7 PF13176.1 ETO24787.1 - 0.36 10.7 3.6 53 3.9 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 ETO24787.1 - 0.36 10.9 17.4 0.036 14.1 1.4 4.1 2 2 3 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Nop14 PF04147.7 ETO24787.1 - 0.81 7.5 8.3 1.1 7.0 5.7 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 ETO24787.1 - 3.1 6.1 10.5 4.5 5.6 7.3 1.1 1 0 0 1 1 1 0 Daxx Family PBP1_TM PF14812.1 ETO24787.1 - 4.3 7.7 12.6 12 6.2 8.7 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 ETO24787.1 - 7.6 6.0 10.1 12 5.3 7.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin CobT PF06213.7 ETO24787.1 - 9.8 5.2 11.9 15 4.6 8.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TPR_11 PF13414.1 ETO24788.1 - 2.5e-16 59.0 16.0 7.3e-08 31.9 0.1 3.0 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETO24788.1 - 4.4e-09 35.5 12.1 0.0076 15.8 0.1 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 ETO24788.1 - 1.3e-08 34.6 7.9 1.9e-06 27.7 0.2 2.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO24788.1 - 2.4e-08 33.1 12.5 0.069 12.9 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO24788.1 - 5.1e-08 32.2 12.3 0.035 14.0 0.3 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO24788.1 - 1.3e-06 28.4 1.2 0.024 15.2 0.0 3.2 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO24788.1 - 2.3e-06 28.1 1.2 0.003 18.1 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO24788.1 - 0.00012 22.0 3.9 0.012 15.7 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO24788.1 - 0.00036 20.7 5.1 0.0077 16.5 0.0 2.9 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO24788.1 - 0.00039 20.0 5.8 1.1 9.1 1.5 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO24788.1 - 0.0045 17.0 7.7 0.019 15.0 1.2 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETO24788.1 - 0.1 13.0 6.3 1.3 9.6 0.9 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO24788.1 - 0.24 10.6 1.6 4.1 6.7 0.3 2.8 3 0 0 3 3 3 0 SHNi-TPR Menin PF05053.8 ETO24788.1 - 3.1 5.8 12.2 3.8 5.5 8.4 1.1 1 0 0 1 1 1 0 Menin TPR_3 PF07720.7 ETO24788.1 - 4.9 7.0 9.2 0.45 10.3 2.3 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.7 ETO24788.1 - 8.3 7.2 6.9 4.1 8.1 0.7 3.0 3 0 0 3 3 3 0 Sel1 repeat Claudin_3 PF06653.6 ETO24789.1 - 0.0093 15.7 1.4 0.015 15.0 1.0 1.4 1 0 0 1 1 1 1 Tight junction protein, Claudin-like Secretin_N_2 PF07655.8 ETO24789.1 - 1.3 9.4 32.9 1.4 9.3 14.7 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain SAP PF02037.22 ETO24792.1 - 5.1e-08 32.2 0.3 9.4e-08 31.3 0.2 1.5 1 0 0 1 1 1 1 SAP domain DUF1090 PF06476.7 ETO24792.1 - 0.16 11.6 10.2 0.29 10.7 7.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) DUF3153 PF11353.3 ETO24792.1 - 1.1 8.6 4.5 1.7 8.0 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) GspL_C PF12693.2 ETO24794.1 - 0.11 12.3 8.3 0.36 10.5 1.7 2.3 2 0 0 2 2 2 0 GspL periplasmic domain Bd3614_N PF14442.1 ETO24794.1 - 0.25 11.3 2.6 0.6 10.0 1.8 1.6 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal Tom22 PF04281.8 ETO24796.1 - 0.013 15.0 0.5 0.013 15.0 0.4 2.5 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 B2-adapt-app_C PF09066.5 ETO24797.1 - 3e-09 36.7 0.0 3e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain Secretin_N_2 PF07655.8 ETO24797.1 - 0.81 10.1 20.9 0.32 11.4 10.5 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain DUF912 PF06024.7 ETO24797.1 - 4.3 7.4 6.8 15 5.7 4.7 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PAP_central PF04928.12 ETO24798.1 - 1.1e-10 40.8 0.1 2.9e-10 39.3 0.0 1.6 2 0 0 2 2 2 1 Poly(A) polymerase central domain BAF1_ABF1 PF04684.8 ETO24799.1 - 0.061 12.1 6.0 0.07 11.9 4.1 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF2547 PF10818.3 ETO24799.1 - 0.13 12.8 10.4 0.23 12.1 7.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2547) TSA PF03249.8 ETO24799.1 - 0.13 10.7 6.6 0.15 10.5 4.6 1.2 1 0 0 1 1 1 0 Type specific antigen BaxI_1 PF12811.2 ETO24799.1 - 0.19 10.8 4.5 0.25 10.4 3.2 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like DUF4557 PF15101.1 ETO24799.1 - 0.2 11.4 7.9 0.23 11.2 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Zip PF02535.17 ETO24799.1 - 0.23 10.4 1.0 0.27 10.1 0.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Pex14_N PF04695.8 ETO24799.1 - 0.24 11.4 9.4 0.38 10.8 6.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Vfa1 PF08432.5 ETO24799.1 - 0.32 11.0 12.3 0.39 10.7 8.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Neur_chan_memb PF02932.11 ETO24799.1 - 0.32 10.8 5.8 0.39 10.5 4.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Saccharop_dh PF03435.13 ETO24799.1 - 0.55 9.1 3.6 0.78 8.6 2.5 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase Med19 PF10278.4 ETO24799.1 - 0.87 9.2 8.3 0.15 11.6 2.0 2.0 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 DUF4407 PF14362.1 ETO24799.1 - 1.2 8.0 11.8 1.5 7.6 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.12 ETO24799.1 - 1.6 7.4 4.8 1.6 7.5 3.3 1.1 1 0 0 1 1 1 0 Presenilin Exo_endo_phos PF03372.18 ETO24803.1 - 4.7e-14 52.9 0.0 1.9e-13 50.9 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ETRAMP PF09716.5 ETO24803.1 - 0.028 14.3 0.9 0.028 14.3 0.6 2.9 4 0 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) DUF843 PF05814.6 ETO24803.1 - 4.9 7.0 9.5 0.44 10.3 0.2 3.3 4 1 0 4 4 4 0 Baculovirus protein of unknown function (DUF843) NT-C2 PF10358.4 ETO24804.1 - 5.6e-09 35.6 1.1 9e-09 34.9 0.4 1.6 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF148 PF02520.12 ETO24805.1 - 0.0025 17.6 5.6 0.0025 17.6 3.9 2.1 1 1 0 2 2 2 1 Domain of unknown function DUF148 IncA PF04156.9 ETO24805.1 - 0.0038 16.8 13.0 0.066 12.7 3.5 2.1 2 0 0 2 2 2 2 IncA protein TPR_MLP1_2 PF07926.7 ETO24805.1 - 0.012 15.3 12.9 0.095 12.4 4.3 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Mitovir_RNA_pol PF05919.6 ETO24805.1 - 0.016 14.2 7.4 0.019 13.9 5.2 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase RILP PF11461.3 ETO24805.1 - 0.024 14.7 2.7 0.024 14.7 1.8 2.2 2 0 0 2 2 2 0 Rab interacting lysosomal protein DUF2899 PF11449.3 ETO24805.1 - 0.026 13.7 1.6 0.029 13.5 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2899) CCDC155 PF14662.1 ETO24805.1 - 0.044 13.3 15.7 0.69 9.4 5.3 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 CENP-Q PF13094.1 ETO24805.1 - 0.049 13.6 10.7 0.43 10.5 0.1 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4515 PF14988.1 ETO24805.1 - 0.052 13.2 15.8 0.076 12.6 4.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) Jnk-SapK_ap_N PF09744.4 ETO24805.1 - 0.063 13.2 11.8 0.77 9.7 0.3 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF2930 PF11152.3 ETO24805.1 - 0.063 12.4 0.1 0.087 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2930) ADIP PF11559.3 ETO24805.1 - 0.065 13.1 20.3 0.54 10.1 5.1 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Lipoprotein_6 PF01441.14 ETO24805.1 - 0.081 12.7 9.8 0.11 12.3 6.0 1.6 1 1 1 2 2 2 0 Lipoprotein Ax_dynein_light PF10211.4 ETO24805.1 - 0.1 12.4 13.8 0.86 9.4 1.1 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain YlqD PF11068.3 ETO24805.1 - 0.14 12.2 16.9 0.075 13.0 4.4 2.1 2 0 0 2 2 2 0 YlqD protein Tropomyosin_1 PF12718.2 ETO24805.1 - 0.18 11.6 19.3 0.8 9.5 1.8 2.2 2 0 0 2 2 2 0 Tropomyosin like DUF3584 PF12128.3 ETO24805.1 - 0.24 8.6 11.1 0.33 8.2 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DOG1 PF14144.1 ETO24805.1 - 0.27 11.3 1.6 1.5 8.8 0.1 2.3 2 0 0 2 2 2 0 Seed dormancy control Flu_NS2 PF00601.14 ETO24805.1 - 0.38 11.0 3.8 0.46 10.7 0.2 2.4 1 1 1 2 2 2 0 Influenza non-structural protein (NS2) Phage_GP20 PF06810.6 ETO24805.1 - 0.49 9.8 18.2 0.15 11.4 4.2 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 Mod_r PF07200.8 ETO24805.1 - 0.54 10.1 16.9 1.2 9.0 4.5 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein APG6 PF04111.7 ETO24805.1 - 0.59 9.1 19.8 0.59 9.1 7.9 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 TMF_DNA_bd PF12329.3 ETO24805.1 - 0.73 9.6 18.2 0.74 9.6 5.4 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Striatin PF08232.7 ETO24805.1 - 0.74 10.1 14.9 10 6.4 10.4 2.0 1 1 0 1 1 1 0 Striatin family TMF_TATA_bd PF12325.3 ETO24805.1 - 0.79 9.4 13.2 1.6 8.5 4.4 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF2403 PF10290.4 ETO24805.1 - 0.79 9.9 3.2 9.5 6.4 0.1 2.3 2 0 0 2 2 2 0 Glycine-rich protein domain (DUF2403) CENP-F_leu_zip PF10473.4 ETO24805.1 - 1 9.1 17.7 1.1 9.1 6.4 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.6 ETO24805.1 - 1.1 9.1 8.8 2 8.3 1.4 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Mnd1 PF03962.10 ETO24805.1 - 1.1 8.8 20.2 61 3.2 14.0 2.1 1 1 0 1 1 1 0 Mnd1 family ERM PF00769.14 ETO24805.1 - 2 7.9 15.5 2.6 7.5 0.6 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family NAD_binding_7 PF13241.1 ETO24805.1 - 2.5 8.4 4.6 7.2 6.9 3.2 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding DUF4446 PF14584.1 ETO24805.1 - 2.8 7.7 8.6 0.39 10.5 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) PRP1_N PF06424.7 ETO24805.1 - 3.6 7.9 8.0 33 4.8 5.5 2.4 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal M_domain PF12938.2 ETO24805.1 - 3.6 7.3 6.1 1.1 8.9 0.8 2.0 2 0 0 2 2 2 0 M domain of GW182 Phage_lysis PF03245.8 ETO24805.1 - 3.7 7.5 9.9 2.6 8.0 2.5 2.1 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein WEMBL PF05701.6 ETO24805.1 - 3.8 5.8 16.5 9.4 4.5 11.4 1.6 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Pyridox_oxase_2 PF12766.2 ETO24805.1 - 4.4 7.6 6.1 11 6.4 4.2 1.8 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase ATG16 PF08614.6 ETO24805.1 - 5.7 6.7 18.7 3.2 7.5 3.2 2.1 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF3450 PF11932.3 ETO24805.1 - 6.2 6.0 17.6 2.9 7.1 4.8 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) bZIP_1 PF00170.16 ETO24805.1 - 7.8 6.5 18.4 2.2 8.2 1.8 3.2 2 2 1 3 3 3 0 bZIP transcription factor DUF1664 PF07889.7 ETO24805.1 - 7.8 6.3 13.0 5.3 6.8 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Tup_N PF08581.5 ETO24805.1 - 9.3 6.5 13.3 17 5.6 5.2 2.4 2 1 0 2 2 2 0 Tup N-terminal DUF4342 PF14242.1 ETO24805.1 - 9.3 6.1 6.6 1.2 8.9 0.4 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4342) Kinetocho_Slk19 PF12709.2 ETO24805.1 - 9.5 6.3 12.7 4.3 7.4 0.3 3.0 2 1 0 2 2 2 0 Central kinetochore-associated DUF1771 PF08590.5 ETO24806.1 - 0.008 16.1 0.3 0.027 14.4 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Sec7 PF01369.15 ETO24807.1 - 2.2e-39 135.1 0.6 2.2e-39 135.1 0.4 1.5 2 0 0 2 2 2 1 Sec7 domain DUF3695 PF12494.3 ETO24807.1 - 0.73 9.5 3.6 2.7 7.7 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3695) Actin PF00022.14 ETO24808.1 - 5.5e-143 476.1 0.0 6.2e-143 475.9 0.0 1.0 1 0 0 1 1 1 1 Actin TPR_12 PF13424.1 ETO24809.1 - 5.4e-49 164.0 2.7 1.5e-24 85.6 0.3 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO24809.1 - 8.1e-30 102.2 2.8 1.5e-15 56.5 0.2 3.6 3 0 0 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETO24809.1 - 2.5e-29 99.6 13.9 2.6e-09 36.3 1.6 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO24809.1 - 7.8e-26 87.7 0.4 2.3e-06 26.9 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO24809.1 - 4.8e-25 85.4 11.9 5.2e-08 32.2 0.8 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO24809.1 - 2.3e-23 81.3 0.0 2.4e-07 30.4 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO24809.1 - 3.3e-21 73.4 16.5 5.4e-09 35.1 2.1 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO24809.1 - 1.2e-10 40.7 1.6 0.0061 16.6 0.0 4.4 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO24809.1 - 1.5e-09 38.2 0.0 2.9e-06 27.7 0.0 2.7 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO24809.1 - 7.9e-09 35.3 6.7 0.0003 21.0 0.3 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO24809.1 - 2.6e-07 30.6 0.0 0.089 13.4 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat PPR PF01535.15 ETO24809.1 - 3.4e-06 26.6 1.2 0.42 10.6 0.0 3.9 3 0 0 3 3 3 2 PPR repeat DUF2225 PF09986.4 ETO24809.1 - 0.00019 20.9 1.3 0.00089 18.7 0.5 2.4 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.13 ETO24809.1 - 0.00025 20.8 1.3 1.6 8.6 0.1 3.9 3 1 1 4 4 4 2 MIT (microtubule interacting and transport) domain TPR_19 PF14559.1 ETO24809.1 - 0.00035 20.8 0.0 0.028 14.7 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.4 ETO24809.1 - 0.099 12.0 8.4 2.9 7.2 0.1 3.8 3 1 1 4 4 4 0 26S proteasome subunit RPN7 Apc3 PF12895.2 ETO24809.1 - 0.14 12.2 2.4 0.77 9.9 0.5 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Sel1 PF08238.7 ETO24809.1 - 0.36 11.5 1.7 4.7 7.9 0.2 3.2 4 0 0 4 4 4 0 Sel1 repeat HSP70 PF00012.15 ETO24810.1 - 1.2e-39 135.7 8.0 2.7e-39 134.5 5.5 1.5 1 1 0 1 1 1 1 Hsp70 protein PARP PF00644.15 ETO24810.1 - 4.1e-09 36.1 0.0 1.4e-08 34.3 0.0 1.9 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain DUF2254 PF10011.4 ETO24811.1 - 0.0012 17.3 0.5 0.0017 16.8 0.3 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2254) ODV-E18 PF10717.4 ETO24811.1 - 0.0075 15.6 0.2 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 WW PF00397.21 ETO24812.1 - 0.0045 16.8 0.0 0.008 16.0 0.0 1.5 1 0 0 1 1 1 1 WW domain DUF1675 PF07897.6 ETO24812.1 - 0.74 9.6 11.6 0.95 9.2 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Bud13 PF09736.4 ETO24812.1 - 1.3 9.2 18.8 1.9 8.7 13.1 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF966 PF06136.8 ETO24812.1 - 1.6 8.0 15.3 2.1 7.7 10.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) TEX19 PF15553.1 ETO24812.1 - 3.2 7.6 5.9 4.3 7.1 4.1 1.2 1 0 0 1 1 1 0 Testis-expressed protein 19 CobT PF06213.7 ETO24812.1 - 3.7 6.6 18.0 5.2 6.1 12.5 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Hid1 PF12722.2 ETO24812.1 - 4.9 4.7 18.1 5.7 4.4 12.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sulfotransfer_2 PF03567.9 ETO24813.1 - 1.4e-10 41.3 0.3 1.9e-10 40.8 0.2 1.3 1 1 0 1 1 1 1 Sulfotransferase family CAP_GLY PF01302.20 ETO24814.1 - 2.5e-05 23.8 0.5 5.2e-05 22.8 0.4 1.5 1 0 0 1 1 1 1 CAP-Gly domain YjgP_YjgQ PF03739.9 ETO24815.1 - 0.14 10.9 8.7 0.17 10.5 6.0 1.3 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family RR_TM4-6 PF06459.7 ETO24815.1 - 0.87 9.4 16.3 1.3 8.8 11.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Utp14 PF04615.8 ETO24815.1 - 1.3 7.1 28.3 1.7 6.6 19.6 1.2 1 0 0 1 1 1 0 Utp14 protein AUX_IAA PF02309.11 ETO24815.1 - 2.1 8.0 17.8 3.9 7.1 12.3 1.6 1 0 0 1 1 1 0 AUX/IAA family BTV_NS2 PF04514.7 ETO24815.1 - 2.9 6.6 12.4 4.1 6.2 8.6 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Ndc1_Nup PF09531.5 ETO24815.1 - 3.2 6.0 28.2 4.7 5.5 19.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PPP4R2 PF09184.6 ETO24815.1 - 9.1 5.7 22.8 16 4.9 15.8 1.5 1 0 0 1 1 1 0 PPP4R2 ECH_C PF13766.1 ETO24816.1 - 2.2e-33 114.9 0.0 4.6e-33 113.8 0.0 1.6 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 ETO24816.1 - 9.4e-26 90.4 0.0 6.6e-25 87.6 0.0 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF2457 PF10446.4 ETO24817.1 - 0.0005 18.9 24.9 0.0005 18.9 17.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) Ycf1 PF05758.7 ETO24817.1 - 0.0027 15.5 6.2 0.003 15.3 4.3 1.1 1 0 0 1 1 1 1 Ycf1 BUD22 PF09073.5 ETO24817.1 - 0.038 13.0 28.1 0.058 12.4 19.5 1.2 1 0 0 1 1 1 0 BUD22 MIP-T3 PF10243.4 ETO24817.1 - 0.046 12.1 18.4 0.06 11.8 12.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 NARP1 PF12569.3 ETO24817.1 - 2.9 6.5 14.9 5.5 5.6 10.3 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Prog_receptor PF02161.10 ETO24817.1 - 4.1 6.1 7.4 5.8 5.6 5.1 1.2 1 0 0 1 1 1 0 Progesterone receptor DUF3245 PF11595.3 ETO24817.1 - 7.6 6.8 23.5 0.76 10.0 6.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Avian_gp85 PF03708.9 ETO24819.1 - 0.46 9.6 7.1 1.3 8.2 0.5 2.2 1 1 1 2 2 2 0 Avian retrovirus envelope protein, gp85 zf-C3HC4_2 PF13923.1 ETO24823.1 - 4.2e-05 23.4 18.1 0.00013 21.9 12.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO24823.1 - 0.00025 20.6 15.9 0.00072 19.1 11.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO24823.1 - 0.0066 16.2 20.8 0.0066 16.2 14.4 2.0 2 0 0 2 2 2 1 Ring finger domain Lysine_decarbox PF03641.9 ETO24823.1 - 0.043 13.6 0.0 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 Possible lysine decarboxylase CompInhib_SCIN PF11546.3 ETO24823.1 - 0.048 13.5 1.6 0.08 12.7 0.2 2.0 2 0 0 2 2 2 0 Staphylococcal complement inhibitor SCIN zf-C3HC4 PF00097.20 ETO24823.1 - 0.12 12.0 16.9 0.4 10.3 11.7 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) U-box PF04564.10 ETO24823.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 U-box domain PDEase_I PF00233.14 ETO24824.1 - 3.7e-52 177.4 8.8 3.5e-26 92.3 0.1 2.8 1 1 1 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Mito_carr PF00153.22 ETO24825.1 - 6.4e-07 28.9 0.1 1.1e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial carrier protein CM_1 PF07736.6 ETO24825.1 - 0.014 15.4 0.1 0.023 14.8 0.1 1.4 1 0 0 1 1 1 0 Chorismate mutase type I DUF4559 PF15112.1 ETO24825.1 - 0.57 9.2 11.2 0.061 12.4 4.8 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) Mito_carr PF00153.22 ETO24826.1 - 1.9e-24 85.1 0.3 1.9e-22 78.7 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein XOO_2897-deam PF14440.1 ETO24827.1 - 0.027 14.1 0.3 0.12 12.0 0.1 2.1 2 0 0 2 2 2 0 Xanthomonas XOO_2897-like deaminase V_ATPase_I PF01496.14 ETO24827.1 - 2 6.1 7.8 2.4 5.9 5.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YebO PF13974.1 ETO24827.1 - 6.9 6.5 6.4 3.3 7.5 0.5 3.2 3 0 0 3 3 3 0 YebO-like protein GCV_T PF01571.16 ETO24828.1 - 1.4e-16 60.4 0.0 1e-15 57.6 0.0 2.1 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 ETO24828.1 - 0.0055 16.7 0.0 0.018 15.0 0.0 2.0 1 1 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain TrmE_N PF10396.4 ETO24828.1 - 0.13 12.2 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 GTP-binding protein TrmE N-terminus Mito_carr PF00153.22 ETO24829.1 - 3.2e-52 174.1 7.6 2.6e-19 68.6 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein UPF0254 PF06787.6 ETO24829.1 - 0.011 15.2 0.3 0.023 14.2 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0254) G-alpha PF00503.15 ETO24831.1 - 4.2e-28 98.1 4.0 6.9e-28 97.4 2.8 1.3 1 1 0 1 1 1 1 G-protein alpha subunit DUF1866 PF08952.6 ETO24831.1 - 0.08 12.4 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) GST_C PF00043.20 ETO24832.1 - 1.8e-08 34.2 0.1 3.2e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETO24832.1 - 0.00014 21.6 0.0 0.00041 20.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 ETO24832.1 - 0.002 18.2 0.1 0.0088 16.1 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 ETO24832.1 - 0.0085 16.5 0.0 0.02 15.3 0.0 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain Mg_trans_NIPA PF05653.9 ETO24833.1 - 1.4e-08 34.0 3.0 1.8e-08 33.7 2.1 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA DUF3392 PF11872.3 ETO24833.1 - 0.088 12.7 1.7 0.14 12.1 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3392) DUF3810 PF12725.2 ETO24833.1 - 0.48 9.2 3.9 0.69 8.7 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Guanylate_cyc PF00211.15 ETO24835.1 - 1.3e-11 44.2 0.0 2.2e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain RR_TM4-6 PF06459.7 ETO24835.1 - 0.13 12.1 18.3 0.26 11.1 12.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FixQ PF05545.6 ETO24835.1 - 0.38 10.4 0.1 0.38 10.4 0.0 2.9 4 0 0 4 4 4 0 Cbb3-type cytochrome oxidase component FixQ Daxx PF03344.10 ETO24835.1 - 2.8 6.3 28.0 4.1 5.7 19.4 1.2 1 0 0 1 1 1 0 Daxx Family 7TMR-DISM_7TM PF07695.6 ETO24835.1 - 3.5 7.2 10.2 4 7.0 0.1 3.1 2 1 1 3 3 3 0 7TM diverse intracellular signalling Hid1 PF12722.2 ETO24835.1 - 4.7 4.7 17.9 6.7 4.2 12.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3953 PF13129.1 ETO24836.1 - 0.06 12.9 0.1 0.06 12.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3953) Pkinase PF00069.20 ETO24838.1 - 7.1e-54 182.6 0.0 9.2e-54 182.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO24838.1 - 1.4e-30 106.2 0.0 1.9e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO24838.1 - 4e-09 35.8 0.1 2.5e-08 33.2 0.0 1.8 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 ETO24838.1 - 4.2e-05 23.3 0.1 9.5e-05 22.2 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 ETO24838.1 - 0.0032 16.5 0.2 0.01 14.9 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 ETO24838.1 - 0.015 14.1 0.0 0.23 10.2 0.0 2.1 2 0 0 2 2 2 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 ETO24838.1 - 0.02 14.2 0.1 0.13 11.6 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL WD40 PF00400.27 ETO24839.1 - 4.4e-74 241.9 11.6 4.7e-12 45.2 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO24839.1 - 1.1e-07 30.4 3.9 0.078 11.1 0.0 5.4 1 1 3 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO24839.1 - 1.8e-07 30.2 6.8 0.0073 15.1 0.4 4.5 1 1 2 3 3 3 3 Nup133 N terminal like eIF2A PF08662.6 ETO24839.1 - 3.6e-06 26.8 0.1 0.00045 19.9 0.0 2.9 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A DUF3601 PF12208.3 ETO24839.1 - 0.0004 20.2 0.1 26 4.8 0.0 4.9 2 2 3 5 5 5 0 Domain of unknown function (DUF3601) PD40 PF07676.7 ETO24839.1 - 0.0042 16.7 2.8 10 5.9 0.0 4.6 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 ETO24839.1 - 0.0071 14.9 0.0 0.25 9.8 0.0 2.6 1 1 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Proteasome_A_N PF10584.4 ETO24839.1 - 0.13 11.5 5.1 15 5.0 0.0 4.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature FH2 PF02181.18 ETO24840.1 - 3e-33 115.2 0.5 5.3e-33 114.4 0.4 1.3 1 0 0 1 1 1 1 Formin Homology 2 Domain DUF2360 PF10152.4 ETO24840.1 - 0.0065 16.7 0.0 0.021 15.1 0.0 1.8 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) DUF2360 PF10152.4 ETO24841.1 - 0.00057 20.1 4.6 0.00076 19.7 3.2 1.2 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) ParB PF08775.5 ETO24841.1 - 0.0035 17.6 1.2 0.0035 17.6 0.8 1.5 2 0 0 2 2 2 1 ParB family IncA PF04156.9 ETO24841.1 - 0.005 16.4 1.0 0.0088 15.6 0.7 1.4 1 0 0 1 1 1 1 IncA protein Laminin_I PF06008.9 ETO24841.1 - 0.014 14.7 1.8 0.021 14.1 1.2 1.2 1 0 0 1 1 1 0 Laminin Domain I SlyX PF04102.7 ETO24841.1 - 0.018 15.4 1.4 0.038 14.3 1.0 1.6 1 1 0 1 1 1 0 SlyX ADIP PF11559.3 ETO24841.1 - 0.023 14.5 2.4 0.023 14.5 1.6 1.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DivIVA PF05103.8 ETO24841.1 - 0.025 14.6 0.8 0.025 14.6 0.5 1.7 2 0 0 2 2 2 0 DivIVA protein TMF_DNA_bd PF12329.3 ETO24841.1 - 0.025 14.3 4.1 0.025 14.3 2.8 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding PspA_IM30 PF04012.7 ETO24841.1 - 0.026 13.8 2.1 0.041 13.2 1.5 1.2 1 0 0 1 1 1 0 PspA/IM30 family DUF904 PF06005.7 ETO24841.1 - 0.029 14.6 0.9 0.029 14.6 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF904) HALZ PF02183.13 ETO24841.1 - 0.056 13.1 4.2 5.8 6.7 2.9 2.4 1 1 0 1 1 1 0 Homeobox associated leucine zipper Spc24 PF08286.6 ETO24841.1 - 0.064 12.9 1.4 0.16 11.7 1.0 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DivIC PF04977.10 ETO24841.1 - 0.13 11.7 3.2 0.29 10.6 2.2 1.7 1 1 0 1 1 1 0 Septum formation initiator Prominin PF05478.6 ETO24841.1 - 0.14 9.6 0.7 0.19 9.2 0.5 1.1 1 0 0 1 1 1 0 Prominin TMF_TATA_bd PF12325.3 ETO24841.1 - 0.22 11.2 3.6 0.086 12.5 0.4 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Fib_alpha PF08702.5 ETO24841.1 - 0.33 11.0 3.0 0.15 12.1 0.7 1.4 2 0 0 2 2 1 0 Fibrinogen alpha/beta chain family Cortex-I_coil PF09304.5 ETO24841.1 - 0.36 10.9 5.2 0.23 11.5 1.3 2.0 2 0 0 2 2 2 0 Cortexillin I, coiled coil Striatin PF08232.7 ETO24841.1 - 0.46 10.7 4.8 1.2 9.4 3.3 1.7 1 1 0 1 1 1 0 Striatin family BRE1 PF08647.6 ETO24841.1 - 0.82 9.6 7.6 0.16 11.9 1.6 1.9 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase ABC_tran_2 PF12848.2 ETO24841.1 - 3.8 7.4 7.5 9.6 6.1 0.4 2.2 2 0 0 2 2 2 0 ABC transporter HALZ PF02183.13 ETO24842.1 - 4.5 7.0 38.1 0.11 12.2 2.2 8.0 7 0 0 7 7 7 0 Homeobox associated leucine zipper UPF0122 PF04297.9 ETO24843.1 - 0.0084 16.1 1.1 0.022 14.7 0.1 2.3 2 0 0 2 2 2 1 Putative helix-turn-helix protein, YlxM / p13 like DUF1510 PF07423.6 ETO24843.1 - 0.017 14.4 16.5 0.31 10.3 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) TPR_11 PF13414.1 ETO24844.1 - 2.2e-19 68.8 28.2 2.5e-06 27.0 0.2 6.5 5 2 2 7 7 7 5 TPR repeat TPR_19 PF14559.1 ETO24844.1 - 6.2e-12 45.6 7.8 2.6e-07 30.8 2.4 6.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO24844.1 - 1.6e-11 43.9 29.4 3.8e-05 23.5 1.4 7.7 7 1 1 8 8 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO24844.1 - 6.6e-11 42.5 1.5 4.5e-07 30.3 1.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO24844.1 - 8.7e-11 40.8 33.5 0.11 12.4 0.0 9.7 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 ETO24844.1 - 3e-10 39.7 1.4 0.0024 18.3 0.0 6.2 5 1 2 7 7 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO24844.1 - 5.7e-09 35.2 24.8 0.37 10.4 0.0 9.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO24844.1 - 1.1e-08 34.5 17.9 4.9e-05 23.2 0.0 5.2 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO24844.1 - 7.8e-06 25.3 23.3 0.22 11.4 0.1 7.9 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO24844.1 - 6.9e-05 22.6 11.9 1.5 8.8 0.6 6.9 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO24844.1 - 0.00015 21.3 7.8 0.99 9.3 0.0 6.5 6 1 1 7 7 7 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO24844.1 - 0.00031 20.8 30.6 0.0086 16.1 2.7 5.4 3 2 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 ETO24844.1 - 0.00042 20.3 0.5 0.02 14.9 1.3 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat DUF4611 PF15387.1 ETO24844.1 - 0.0031 17.6 0.1 0.0091 16.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) PPR PF01535.15 ETO24844.1 - 0.11 12.5 1.5 41 4.4 0.0 4.2 4 0 0 4 4 4 0 PPR repeat DUF1374 PF07118.6 ETO24844.1 - 0.25 11.4 7.0 0.049 13.7 1.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1374) Sel1 PF08238.7 ETO24844.1 - 0.39 11.4 2.6 10 6.9 0.0 3.8 3 0 0 3 3 3 0 Sel1 repeat Kelch_3 PF13415.1 ETO24845.1 - 4.1e-06 26.7 0.0 4e-05 23.6 0.0 2.8 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO24845.1 - 7.4e-06 25.6 0.7 0.00031 20.4 0.0 3.2 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO24845.1 - 1.2e-05 24.7 1.7 1.2e-05 24.7 1.2 3.9 4 1 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 ETO24845.1 - 0.00017 21.6 6.5 0.6 10.3 0.3 4.5 3 1 1 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO24845.1 - 0.019 14.6 8.6 2.8 7.8 0.4 4.8 4 1 0 4 4 4 0 Kelch motif ECH PF00378.15 ETO24846.1 - 2.8e-28 98.6 0.0 3.4e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF1831 PF08866.5 ETO24846.1 - 0.19 11.9 3.8 0.093 13.0 0.6 2.0 2 0 0 2 2 2 0 Putative amino acid metabolism Pkinase PF00069.20 ETO24848.1 - 7.5e-14 51.4 0.6 8.1e-08 31.7 0.1 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO24848.1 - 0.0032 16.5 0.1 0.38 9.7 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase APC8 PF04049.8 ETO24848.1 - 0.072 12.8 0.8 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 Anaphase promoting complex subunit 8 / Cdc23 Ank_2 PF12796.2 ETO24849.1 - 7e-23 80.7 0.2 2.6e-16 59.7 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETO24849.1 - 6.6e-22 76.1 1.7 3.5e-07 29.6 0.0 4.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 ETO24849.1 - 3.1e-17 62.5 0.4 8.9e-09 35.6 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO24849.1 - 5.6e-17 60.1 1.3 1.9e-06 27.5 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 ETO24849.1 - 1.5e-14 53.6 0.8 2.2e-06 27.7 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Pro-rich_19 PF15455.1 ETO24849.1 - 0.0094 15.0 0.0 0.012 14.6 0.0 1.1 1 0 0 1 1 1 1 Proline-rich 19 XPG_N PF00752.12 ETO24851.1 - 0.029 14.6 0.3 0.058 13.6 0.2 1.5 1 0 0 1 1 1 0 XPG N-terminal domain DUF2270 PF10028.4 ETO24851.1 - 0.1 12.0 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2270) CheZ PF04344.8 ETO24851.1 - 0.34 10.5 5.4 0.23 11.1 0.3 2.1 1 1 1 2 2 2 0 Chemotaxis phosphatase, CheZ DUF3139 PF11337.3 ETO24851.1 - 0.35 11.1 3.5 3.9 7.8 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) DUF2203 PF09969.4 ETO24851.1 - 1.9 8.7 5.7 16 5.7 0.2 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) CD34_antigen PF06365.7 ETO24851.1 - 2.8 7.5 10.0 0.73 9.4 4.0 1.8 1 1 0 2 2 2 0 CD34/Podocalyxin family Occludin_ELL PF07303.8 ETO24852.1 - 0.0072 17.0 5.5 0.75 10.5 0.4 2.8 1 1 2 3 3 3 2 Occludin homology domain COMP PF11598.3 ETO24852.1 - 0.021 14.8 1.8 0.031 14.3 0.2 2.1 2 0 0 2 2 1 0 Cartilage oligomeric matrix protein TMF_TATA_bd PF12325.3 ETO24852.1 - 0.03 14.0 4.5 0.024 14.3 1.3 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Vinculin PF01044.14 ETO24852.1 - 0.032 12.2 2.3 0.038 12.0 1.6 1.2 1 0 0 1 1 1 0 Vinculin family Filament PF00038.16 ETO24852.1 - 0.038 13.4 9.2 0.048 13.1 6.4 1.2 1 0 0 1 1 1 0 Intermediate filament protein Phage_int_SAM_1 PF02899.12 ETO24852.1 - 0.062 13.4 0.2 0.23 11.6 0.1 2.1 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Reo_sigmaC PF04582.7 ETO24852.1 - 0.063 12.4 0.1 0.069 12.3 0.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein PSCyt3 PF07627.6 ETO24852.1 - 0.079 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) Syntaxin-6_N PF09177.6 ETO24852.1 - 0.09 13.1 6.3 2.1 8.7 0.9 3.2 1 1 2 3 3 3 0 Syntaxin 6, N-terminal MutS_III PF05192.13 ETO24852.1 - 0.13 12.0 4.9 0.16 11.6 3.4 1.1 1 0 0 1 1 1 0 MutS domain III Mod_r PF07200.8 ETO24852.1 - 0.14 12.0 8.0 0.34 10.8 4.2 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TraH PF06122.6 ETO24852.1 - 0.14 10.9 2.2 2 7.1 0.7 2.2 2 1 0 2 2 2 0 Conjugative relaxosome accessory transposon protein Laminin_II PF06009.7 ETO24852.1 - 0.14 11.8 7.9 0.26 11.0 1.8 2.1 1 1 1 2 2 2 0 Laminin Domain II DivIVA PF05103.8 ETO24852.1 - 0.2 11.6 7.5 3 7.9 0.2 2.7 1 1 1 2 2 2 0 DivIVA protein Tweety PF04906.8 ETO24852.1 - 0.25 9.7 2.3 0.33 9.3 1.6 1.1 1 0 0 1 1 1 0 Tweety Dor1 PF04124.7 ETO24852.1 - 0.26 9.7 8.0 0.17 10.2 3.2 2.1 1 1 1 2 2 2 0 Dor1-like family EcoEI_R_C PF08463.5 ETO24852.1 - 0.51 10.1 7.8 0.43 10.4 1.5 2.3 2 0 0 2 2 2 0 EcoEI R protein C-terminal DUF1664 PF07889.7 ETO24852.1 - 0.53 10.0 3.5 1.3 8.8 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.1 ETO24852.1 - 0.55 10.5 8.9 0.12 12.7 2.2 2.5 1 1 2 3 3 3 0 Snapin/Pallidin Fib_alpha PF08702.5 ETO24852.1 - 0.59 10.2 9.4 1.1 9.3 2.3 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family IncA PF04156.9 ETO24852.1 - 0.69 9.4 2.5 3.3 7.2 1.7 1.9 1 1 0 1 1 1 0 IncA protein DUF948 PF06103.6 ETO24852.1 - 1.5 8.7 6.7 18 5.2 1.2 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF342 PF03961.8 ETO24852.1 - 1.9 6.7 8.2 1.4 7.2 3.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Baculo_PEP_C PF04513.7 ETO24852.1 - 2 8.2 12.3 2.6 7.8 7.8 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 ETO24852.1 - 3.6 7.8 5.7 7.4 6.9 0.8 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Fzo_mitofusin PF04799.8 ETO24852.1 - 4.1 6.7 9.3 0.99 8.7 2.4 2.3 1 1 1 2 2 2 0 fzo-like conserved region DUF972 PF06156.8 ETO24852.1 - 4.5 7.6 9.4 2.6 8.4 2.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Pex19 PF04614.7 ETO24853.1 - 4.1e-08 33.1 2.1 4.1e-08 33.1 1.5 1.7 1 1 0 1 1 1 1 Pex19 protein family Laminin_II PF06009.7 ETO24853.1 - 0.025 14.3 1.1 0.025 14.3 0.7 1.9 2 1 0 2 2 2 0 Laminin Domain II AXE1 PF05448.7 ETO24853.1 - 0.079 11.4 0.4 0.1 11.0 0.3 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Mem_trans PF03547.13 ETO24854.1 - 5.2 5.2 10.0 34 2.5 4.4 2.8 2 1 0 2 2 2 0 Membrane transport protein WD40 PF00400.27 ETO24855.1 - 2.5e-17 62.0 2.5 1.8e-08 33.9 0.6 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat PH PF00169.24 ETO24856.1 - 2.6e-11 43.6 0.2 4.5e-11 42.8 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 ETO24856.1 - 2.6e-06 27.6 2.5 6.8e-05 23.0 1.7 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 ETO24856.1 - 0.00018 21.3 0.8 0.0003 20.6 0.1 1.8 1 1 1 2 2 2 1 PH domain PH_8 PF15409.1 ETO24856.1 - 0.0017 18.4 0.8 0.016 15.2 0.5 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_7 PF15408.1 ETO24856.1 - 0.085 12.7 0.0 0.25 11.2 0.0 1.8 1 1 0 1 1 1 0 Pleckstrin homology domain ORC6 PF05460.8 ETO24857.1 - 0.002 17.2 0.1 0.002 17.2 0.1 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) DUF2413 PF10310.4 ETO24857.1 - 0.0043 15.9 3.4 0.0053 15.6 2.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) VTC PF09359.5 ETO24857.1 - 0.013 14.5 1.8 0.017 14.1 1.2 1.2 1 0 0 1 1 1 0 VTC domain Myc_target_1 PF15179.1 ETO24857.1 - 0.013 15.0 0.0 0.029 13.9 0.0 1.5 1 1 0 1 1 1 0 Myc target protein 1 Fmp27 PF10344.4 ETO24857.1 - 0.016 12.9 0.2 0.018 12.7 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 DUF2937 PF11157.3 ETO24857.1 - 0.08 12.2 0.1 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) QLQ PF08880.6 ETO24857.1 - 0.089 12.2 0.2 0.24 10.8 0.2 1.7 1 0 0 1 1 1 0 QLQ Senescence_reg PF04520.8 ETO24857.1 - 0.18 12.2 3.0 0.29 11.6 1.9 1.4 2 0 0 2 2 2 0 Senescence regulator RNA_pol_L PF01193.19 ETO24858.1 - 8e-09 34.5 0.0 1.2e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_bac PF01000.21 ETO24858.1 - 8.4e-08 32.3 0.0 1.8e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain Pex19 PF04614.7 ETO24859.1 - 4.1e-09 36.4 12.8 8.7e-09 35.3 7.9 2.1 1 1 0 1 1 1 1 Pex19 protein family DUF87 PF01935.12 ETO24860.1 - 1.1 8.9 7.3 1.4 8.7 3.7 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF87 Peptidase_S49_N PF08496.5 ETO24860.1 - 2.9 7.6 6.5 5.3 6.8 4.5 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal GTP_EFTU_D2 PF03144.20 ETO24861.1 - 0.00083 19.4 2.1 0.00095 19.2 0.2 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Coatomer_WDAD PF04053.9 ETO24862.1 - 2.1e-105 353.1 0.2 3.1e-105 352.5 0.1 1.2 1 0 0 1 1 1 1 Coatomer WD associated region TPR_11 PF13414.1 ETO24862.1 - 0.12 12.0 0.5 0.7 9.5 0.1 2.3 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 ETO24863.1 - 4.1e-13 48.1 18.7 2.9e-05 23.6 0.6 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO24863.1 - 1.4e-11 44.6 6.7 9.6e-08 32.5 1.3 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO24863.1 - 9e-11 40.9 18.4 9.8e-06 24.9 0.7 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO24863.1 - 1.6e-10 40.4 13.0 1.5e-05 24.5 2.8 3.5 2 1 0 3 3 3 2 TPR repeat TPR_14 PF13428.1 ETO24863.1 - 4e-10 39.3 3.1 0.00098 19.5 0.1 4.3 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO24863.1 - 2.3e-08 33.6 4.9 0.021 15.0 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO24863.1 - 2.9e-08 33.9 0.6 0.31 11.4 0.0 3.5 2 1 1 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO24863.1 - 2.3e-06 26.9 9.9 0.00019 20.9 0.3 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO24863.1 - 2.5e-06 27.3 11.8 0.00014 21.7 1.4 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO24863.1 - 6.6e-05 22.4 15.5 0.0059 16.3 0.2 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO24863.1 - 9.6e-05 22.4 7.9 0.0023 18.0 1.9 3.0 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETO24863.1 - 0.0012 19.1 14.2 0.27 11.7 0.2 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat RPN7 PF10602.4 ETO24863.1 - 0.0014 18.0 2.3 0.026 13.8 0.1 2.8 1 1 2 3 3 3 1 26S proteasome subunit RPN7 TPR_15 PF13429.1 ETO24863.1 - 0.012 14.6 3.6 0.054 12.5 0.4 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.15 ETO24863.1 - 0.046 13.7 1.9 0.077 13.0 0.0 2.4 3 0 0 3 3 2 0 PPR repeat BTAD PF03704.12 ETO24863.1 - 0.68 10.2 3.1 0.42 10.8 0.6 1.7 2 0 0 2 2 2 0 Bacterial transcriptional activator domain MIT PF04212.13 ETO24863.1 - 3.2 7.6 6.1 0.4 10.5 0.3 2.4 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain DUF2076 PF09849.4 ETO24863.1 - 9 6.2 9.2 14 5.6 6.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) UPF0262 PF06793.7 ETO24864.1 - 0.066 12.9 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) Rox3 PF08633.5 ETO24867.1 - 0.035 14.4 5.7 0.07 13.4 3.9 1.5 1 0 0 1 1 1 0 Rox3 mediator complex subunit Tir_receptor_C PF07489.6 ETO24867.1 - 0.26 11.0 11.0 0.41 10.3 7.6 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus SpoIIIAH PF12685.2 ETO24868.1 - 0.026 14.0 0.7 0.037 13.5 0.5 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Shisa PF13908.1 ETO24868.1 - 0.3 11.2 8.0 0.5 10.5 5.6 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Suf PF05843.9 ETO24868.1 - 0.64 9.7 6.0 0.88 9.2 4.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Herpes_DNAp_acc PF04929.7 ETO24868.1 - 0.76 8.6 6.8 1.2 8.0 4.7 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor MCPVI PF02993.9 ETO24868.1 - 0.87 9.6 8.7 1.2 9.2 6.1 1.1 1 0 0 1 1 1 0 Minor capsid protein VI PAT1 PF09770.4 ETO24868.1 - 2.6 6.1 20.5 3.4 5.7 14.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Secretin_N_2 PF07655.8 ETO24869.1 - 7.9 6.9 16.9 7.1 7.0 3.3 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain Misat_Tub_SegII PF10644.4 ETO24872.1 - 4.8e-12 45.9 3.8 3.3e-08 33.5 0.4 2.7 1 1 0 2 2 2 2 Misato Segment II tubulin-like domain Kelch_4 PF13418.1 ETO24873.1 - 1.4e-28 98.3 0.2 3.9e-11 42.5 0.0 3.1 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO24873.1 - 4.9e-26 90.2 0.1 9.1e-10 38.4 0.0 3.2 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO24873.1 - 4.7e-21 74.0 1.8 6e-09 35.6 0.2 3.3 1 1 2 3 3 3 3 Kelch motif Kelch_5 PF13854.1 ETO24873.1 - 6.3e-19 67.5 0.0 2.2e-06 27.4 0.1 3.5 3 0 0 3 3 3 3 Kelch motif Kelch_1 PF01344.20 ETO24873.1 - 7.6e-15 54.1 0.1 2.1e-07 30.3 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 ETO24873.1 - 7.5e-11 41.3 0.6 0.0044 16.7 0.0 3.3 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.1 ETO24874.1 - 5.2e-06 26.1 0.1 1e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO24874.1 - 0.00016 21.7 0.0 0.0046 17.0 0.0 2.3 2 0 0 2 2 2 1 Galactose oxidase, central domain Pkinase PF00069.20 ETO24874.1 - 0.00087 18.5 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kelch_1 PF01344.20 ETO24874.1 - 0.042 13.3 0.0 0.091 12.3 0.0 1.5 2 0 0 2 2 2 0 Kelch motif CPSF_A PF03178.10 ETO24875.1 - 5.6e-41 140.6 0.6 3e-17 62.6 0.1 3.3 3 0 0 3 3 3 3 CPSF A subunit region Uteroglobin PF01099.12 ETO24877.1 - 0.011 15.5 0.3 0.033 13.9 0.0 1.9 2 0 0 2 2 2 0 Uteroglobin family DUF1643 PF07799.7 ETO24877.1 - 0.015 14.9 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1643) Mannosyl_trans3 PF11051.3 ETO24877.1 - 0.027 13.8 0.1 0.043 13.1 0.0 1.3 1 1 0 1 1 1 0 Mannosyltransferase putative PUB PF09409.5 ETO24878.1 - 2.2e-10 40.1 0.1 8.5e-10 38.2 0.0 2.0 2 0 0 2 2 2 1 PUB domain His_Phos_1 PF00300.17 ETO24878.1 - 0.0013 18.7 0.0 0.003 17.6 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Cas_GSU0054 PF09609.5 ETO24879.1 - 0.15 10.8 2.0 0.22 10.3 1.4 1.2 1 0 0 1 1 1 0 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) Baculo_PEP_C PF04513.7 ETO24879.1 - 2.3 8.0 15.3 0.78 9.5 0.2 3.8 1 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1198 PF06711.6 ETO24879.1 - 3.5 7.4 6.9 1.7 8.4 2.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1198) YvrJ PF12841.2 ETO24879.1 - 3.7 6.9 6.2 2.1 7.6 0.1 3.5 4 0 0 4 4 4 0 YvrJ protein family LXG PF04740.7 ETO24879.1 - 7.3 6.3 43.3 0.25 11.1 4.8 3.9 1 1 2 3 3 3 0 LXG domain of WXG superfamily GCV_T PF01571.16 ETO24881.1 - 8.8e-10 38.3 0.0 1.5e-08 34.2 0.0 2.2 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 ETO24881.1 - 1.1e-07 31.7 0.0 1.6e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Arginase PF00491.16 ETO24882.1 - 1.8e-49 168.4 0.0 2.2e-49 168.2 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 ETO24882.1 - 0.0027 17.9 0.4 0.062 13.5 0.1 2.1 1 1 0 2 2 2 1 UPF0489 domain WD40 PF00400.27 ETO24883.1 - 5.2e-155 498.4 31.8 2.1e-14 52.7 0.0 14.2 14 0 0 14 14 14 14 WD domain, G-beta repeat Nup160 PF11715.3 ETO24883.1 - 1.4e-17 63.0 16.6 0.032 12.3 0.3 9.3 2 2 5 8 8 8 7 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO24883.1 - 1.9e-14 53.7 5.9 0.00016 21.2 0.0 5.8 2 2 2 5 5 5 4 PQQ-like domain Cytochrom_D1 PF02239.11 ETO24883.1 - 1.9e-09 36.3 7.7 0.017 13.4 0.0 5.4 2 2 2 5 5 5 2 Cytochrome D1 heme domain DPPIV_N PF00930.16 ETO24883.1 - 1.9e-07 29.9 0.9 8 4.9 0.0 7.2 2 2 5 7 7 7 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nbas_N PF15492.1 ETO24883.1 - 1e-06 28.0 3.7 2.7 7.0 0.0 6.1 2 2 1 5 5 5 2 Neuroblastoma-amplified sequence, N terminal TFIIIC_delta PF12657.2 ETO24883.1 - 0.0005 19.8 6.1 0.15 11.7 0.1 4.2 3 1 1 4 4 4 1 Transcription factor IIIC subunit delta N-term PD40 PF07676.7 ETO24883.1 - 0.0012 18.4 16.7 14 5.4 0.1 9.5 12 0 0 12 12 12 0 WD40-like Beta Propeller Repeat PS_Dcarbxylase PF02666.10 ETO24883.1 - 0.0013 18.0 2.1 0.11 11.8 0.0 4.5 4 2 0 4 4 4 1 Phosphatidylserine decarboxylase Resistin PF06954.6 ETO24883.1 - 0.0018 18.4 1.0 14 6.0 0.0 5.8 6 3 3 9 9 8 0 Resistin PA14 PF07691.7 ETO24883.1 - 0.019 14.5 0.8 1.9 8.1 0.0 3.1 3 0 0 3 3 3 0 PA14 domain DUF3732 PF12532.3 ETO24883.1 - 0.043 13.3 7.6 15 5.0 0.1 5.4 4 2 2 6 6 6 0 Protein of unknown function (DUF3732) Proteasome_A_N PF10584.4 ETO24883.1 - 0.5 9.7 14.1 23 4.4 0.0 6.9 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature Fib_alpha PF08702.5 ETO24883.1 - 0.58 10.2 3.7 0.48 10.5 0.2 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TIG PF01833.19 ETO24884.1 - 0.01 15.7 4.3 0.026 14.4 0.6 2.9 2 1 0 2 2 2 0 IPT/TIG domain POT1 PF02765.12 ETO24885.1 - 1.2e-06 28.4 2.6 1.5e-06 28.2 0.1 2.3 2 1 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.20 ETO24885.1 - 0.0052 16.6 0.3 0.43 10.4 0.0 2.8 2 0 0 2 2 2 2 OB-fold nucleic acid binding domain Kinesin PF00225.18 ETO24886.1 - 3.8e-62 209.9 0.7 4.7e-62 209.6 0.5 1.0 1 0 0 1 1 1 1 Kinesin motor domain DUF778 PF05608.7 ETO24886.1 - 0.087 12.7 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF778) PEHE PF15275.1 ETO24887.1 - 0.054 13.9 2.3 0.073 13.5 1.6 1.1 1 0 0 1 1 1 0 PEHE domain DUF4496 PF14908.1 ETO24887.1 - 0.092 12.6 1.1 0.12 12.3 0.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4496) DUF4604 PF15377.1 ETO24887.1 - 0.11 12.6 10.9 0.14 12.4 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) PABP PF00658.13 ETO24888.1 - 6.7e-09 35.2 0.0 1.9e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain Macoilin PF09726.4 ETO24888.1 - 0.77 7.9 20.0 1.1 7.3 13.9 1.3 1 0 0 1 1 1 0 Transmembrane protein SR-25 PF10500.4 ETO24888.1 - 1.3 8.4 15.6 3.3 7.1 10.8 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SprA-related PF12118.3 ETO24888.1 - 2.6 7.3 18.9 0.67 9.2 2.5 2.3 2 0 0 2 2 2 0 SprA-related family DUF4031 PF13223.1 ETO24889.1 - 0.067 13.3 0.1 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4031) Secretin_N_2 PF07655.8 ETO24891.1 - 0.67 10.3 26.9 0.051 13.9 13.3 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain GCD14 PF08704.5 ETO24891.1 - 8.1 5.8 6.4 1.3 8.4 2.0 1.4 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Ribosomal_L6e PF01159.14 ETO24892.1 - 1.2 9.3 12.3 0.12 12.5 3.3 2.8 3 0 0 3 3 3 0 Ribosomal protein L6e Nucleotid_trans PF03407.11 ETO24893.1 - 6.5e-17 62.0 0.2 2.2e-16 60.2 0.1 1.9 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Peptidase_C14 PF00656.17 ETO24895.1 - 2.4e-10 40.5 0.6 5.8e-10 39.2 0.4 1.6 1 0 0 1 1 1 1 Caspase domain Kelch_5 PF13854.1 ETO24895.1 - 0.00096 19.0 1.1 0.53 10.3 0.0 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO24895.1 - 0.23 11.7 5.6 2 8.7 0.1 4.1 4 0 0 4 4 4 0 Kelch motif zf-C3HC4_2 PF13923.1 ETO24896.1 - 0.0075 16.2 6.4 0.053 13.5 4.5 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1413 PF07205.6 ETO24896.1 - 0.012 15.1 0.3 5.9 6.5 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1413) CTDII PF01556.13 ETO24897.1 - 5.4e-14 51.8 0.3 2.1e-13 49.9 0.1 2.0 2 0 0 2 2 2 1 DnaJ C terminal domain 2OG-FeII_Oxy_4 PF13661.1 ETO24897.1 - 0.0073 15.9 0.4 0.62 9.7 0.0 2.5 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily WD40 PF00400.27 ETO24900.1 - 3.1e-55 182.1 25.5 1.1e-11 44.0 1.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO24900.1 - 4e-07 28.5 5.2 1.4 6.9 0.1 5.0 1 1 4 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO24900.1 - 0.0047 15.7 11.6 1.7 7.2 0.2 3.8 1 1 2 3 3 3 2 Nup133 N terminal like Kelch_6 PF13964.1 ETO24900.1 - 0.064 13.4 14.7 5.9 7.2 0.1 5.8 5 1 1 6 6 6 0 Kelch motif HAD PF12710.2 ETO24900.1 - 0.95 9.5 4.3 16 5.6 0.1 3.0 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase p450 PF00067.17 ETO24901.1 - 4.1e-51 173.9 0.1 5.4e-51 173.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_5 PF12695.2 ETO24902.1 - 6.3e-15 55.1 0.0 2.1e-14 53.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 ETO24902.1 - 1.8e-06 27.7 0.0 3.1e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETO24902.1 - 2.1e-06 27.7 0.0 5.3e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 ETO24902.1 - 4e-06 26.4 0.6 0.051 12.9 0.0 3.1 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 ETO24902.1 - 2.1e-05 23.8 0.0 0.00072 18.8 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 ETO24902.1 - 9.9e-05 22.0 0.0 0.00021 20.9 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold UPF0227 PF05728.7 ETO24902.1 - 0.0081 15.9 0.4 0.37 10.4 0.1 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) BAAT_C PF08840.6 ETO24902.1 - 0.011 15.4 0.6 1.3 8.7 0.0 2.1 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2305 PF10230.4 ETO24902.1 - 0.024 14.0 0.7 0.19 11.1 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) PARP PF00644.15 ETO24902.1 - 0.059 12.7 0.1 4.3 6.7 0.0 2.9 3 0 0 3 3 3 0 Poly(ADP-ribose) polymerase catalytic domain HSP70 PF00012.15 ETO24903.1 - 8.6e-23 80.0 1.6 3.7e-22 78.0 1.1 1.8 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 ETO24903.1 - 0.00014 20.5 0.0 0.00062 18.4 0.0 1.8 2 0 0 2 2 2 1 MreB/Mbl protein Peptidase_S24 PF00717.18 ETO24903.1 - 0.062 12.9 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Peptidase S24-like PCP_red PF08369.5 ETO24903.1 - 0.1 12.4 0.1 0.26 11.1 0.1 1.7 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit MutS_III PF05192.13 ETO24904.1 - 6.7e-30 104.4 3.1 1e-29 103.8 2.2 1.3 1 0 0 1 1 1 1 MutS domain III MutS_V PF00488.16 ETO24904.1 - 4.1e-19 68.9 0.0 6.6e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_IV PF05190.13 ETO24904.1 - 2.4e-05 24.4 0.2 7.5e-05 22.8 0.1 2.0 1 0 0 1 1 1 1 MutS family domain IV AAA_14 PF13173.1 ETO24904.1 - 0.0026 17.6 0.5 0.2 11.5 0.0 3.1 2 0 0 2 2 2 1 AAA domain ATP-synt_8 PF00895.15 ETO24905.1 - 1.1 9.4 3.5 7.4 6.8 0.1 2.9 2 0 0 2 2 2 0 ATP synthase protein 8 Pkinase PF00069.20 ETO24906.1 - 3.5e-58 196.8 0.0 4.4e-58 196.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO24906.1 - 6.1e-29 100.8 0.0 8.4e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO24906.1 - 5e-06 25.6 0.0 7.4e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like cNMP_binding PF00027.24 ETO24907.1 - 6.6e-13 48.2 0.2 1.7e-07 30.9 0.0 3.3 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Nop14 PF04147.7 ETO24907.1 - 0.0093 13.9 14.0 0.012 13.5 9.7 1.1 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 ETO24907.1 - 0.034 12.6 19.6 0.046 12.2 13.6 1.1 1 0 0 1 1 1 0 Daxx Family DUF572 PF04502.8 ETO24907.1 - 0.052 12.7 15.0 0.077 12.1 10.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) CDC45 PF02724.9 ETO24907.1 - 0.23 9.4 9.1 0.3 9.0 6.3 1.2 1 0 0 1 1 1 0 CDC45-like protein SSP160 PF06933.6 ETO24907.1 - 1.5 6.7 19.9 2.3 6.0 13.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TFIIF_alpha PF05793.7 ETO24907.1 - 3.4 5.9 26.7 0.12 10.7 13.7 1.8 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Mucin PF01456.12 ETO24907.1 - 8.5 6.1 32.4 16 5.2 22.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein PH PF00169.24 ETO24908.1 - 0.016 15.3 2.1 0.042 14.0 1.5 1.9 1 1 0 1 1 1 0 PH domain CLU PF13236.1 ETO24908.1 - 0.034 13.5 0.0 0.067 12.6 0.0 1.5 1 0 0 1 1 1 0 Clustered mitochondria Cyt-b5 PF00173.23 ETO24909.1 - 2.4e-08 33.6 0.0 4.6e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain WD40 PF00400.27 ETO24911.1 - 3.5e-16 58.3 4.1 0.00016 21.4 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat FH2 PF02181.18 ETO24912.1 - 8.3e-66 222.3 9.3 8.3e-66 222.3 6.4 3.3 4 0 0 4 4 4 1 Formin Homology 2 Domain DUF2360 PF10152.4 ETO24912.1 - 1.1e-08 35.5 10.2 1.3e-06 28.7 0.9 6.2 4 2 1 5 5 5 3 Predicted coiled-coil domain-containing protein (DUF2360) MIP-T3 PF10243.4 ETO24912.1 - 3.8e-08 32.2 54.4 3.8e-08 32.2 37.7 3.1 3 0 0 3 3 3 1 Microtubule-binding protein MIP-T3 SSP160 PF06933.6 ETO24912.1 - 6 4.7 8.9 11 3.7 6.2 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Drf_GBD PF06371.8 ETO24913.1 - 3.9e-05 23.0 0.1 4.4e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain PHAT PF09246.5 ETO24913.1 - 0.066 12.8 0.0 0.077 12.6 0.0 1.1 1 0 0 1 1 1 0 PHAT PI3_PI4_kinase PF00454.22 ETO24915.1 - 3.7e-05 23.3 2.8 0.00024 20.6 1.8 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase ATP-synt_A PF00119.15 ETO24915.1 - 0.00028 20.4 0.7 0.00037 20.0 0.5 1.2 1 0 0 1 1 1 1 ATP synthase A chain Vps51 PF08700.6 ETO24915.1 - 0.076 12.8 0.6 4.5 7.1 0.1 2.4 2 0 0 2 2 2 0 Vps51/Vps67 Tim54 PF11711.3 ETO24917.1 - 0.14 10.6 3.0 0.2 10.1 2.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Serinc PF03348.10 ETO24917.1 - 0.23 10.1 3.0 0.26 9.9 2.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Peroxin-13_N PF04088.8 ETO24917.1 - 2 8.3 5.7 52 3.7 4.0 2.2 1 1 0 1 1 1 0 Peroxin 13, N-terminal region DUF4551 PF15087.1 ETO24917.1 - 2.5 6.3 7.8 3.2 5.9 5.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Glyco_transf_92 PF01697.22 ETO24918.1 - 2.2e-19 69.8 5.2 4.5e-19 68.8 3.6 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.1 ETO24918.1 - 1.6e-05 25.1 3.2 4.3e-05 23.7 1.3 2.4 2 1 0 2 2 2 1 Glycosyl transferase family 2 DUF3439 PF11921.3 ETO24919.1 - 0.018 14.8 0.8 0.037 13.7 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Pkinase PF00069.20 ETO24920.1 - 9.8e-11 41.2 0.0 1.6e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain MRP-63 PF14978.1 ETO24921.1 - 3.9 7.9 12.6 0.2 12.1 3.2 2.2 2 1 0 2 2 2 0 Mitochondrial ribosome protein 63 Trypan_glycop PF00913.14 ETO24921.1 - 5 5.9 9.7 7.9 5.2 6.7 1.3 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) DUF4642 PF15484.1 ETO24921.1 - 5.9 6.8 13.3 7.9 6.4 1.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4642) Tropomodulin PF03250.9 ETO24921.1 - 9.8 5.6 8.0 2.3 7.7 3.3 1.5 2 0 0 2 2 2 0 Tropomodulin CDC45 PF02724.9 ETO24922.1 - 1.9e-05 22.9 0.4 1.9e-05 22.9 0.3 1.1 1 0 0 1 1 1 1 CDC45-like protein RRN3 PF05327.6 ETO24922.1 - 0.00042 18.5 3.3 0.00053 18.2 2.3 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 SAPS PF04499.10 ETO24922.1 - 0.013 14.2 0.3 0.013 14.2 0.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Raftlin PF15250.1 ETO24922.1 - 0.11 11.0 4.7 0.13 10.7 3.3 1.1 1 0 0 1 1 1 0 Raftlin TRAP_alpha PF03896.11 ETO24922.1 - 0.14 11.1 6.5 0.3 10.0 4.5 1.6 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FancD2 PF14631.1 ETO24922.1 - 0.24 8.4 4.0 0.29 8.2 2.8 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease CobT PF06213.7 ETO24922.1 - 0.24 10.5 16.8 0.31 10.1 11.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pox_Ag35 PF03286.9 ETO24922.1 - 0.37 10.2 13.7 0.5 9.8 9.5 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Trypan_PARP PF05887.6 ETO24922.1 - 0.68 9.7 6.5 1 9.2 4.5 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Nop14 PF04147.7 ETO24922.1 - 1.7 6.4 17.9 2.1 6.1 12.4 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 ETO24922.1 - 5.9 5.2 14.8 6.8 5.0 10.3 1.1 1 0 0 1 1 1 0 Daxx Family Sporozoite_P67 PF05642.6 ETO24922.1 - 7.4 4.2 15.1 10 3.8 10.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NPR3 PF03666.8 ETO24922.1 - 8.1 4.8 12.1 11 4.4 8.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RGS PF00615.14 ETO24923.1 - 0.012 15.6 2.9 1.3 9.1 2.0 2.4 1 1 0 1 1 1 0 Regulator of G protein signaling domain Prenylcys_lyase PF07156.9 ETO24924.1 - 0.031 13.1 2.1 0.043 12.6 1.2 1.4 1 1 0 1 1 1 0 Prenylcysteine lyase Baculo_11_kDa PF06143.6 ETO24924.1 - 0.5 9.7 5.1 3.4 7.0 0.1 2.8 3 0 0 3 3 3 0 Baculovirus 11 kDa family Tropomyosin_1 PF12718.2 ETO24925.1 - 0.0024 17.7 3.8 0.0024 17.7 2.6 2.2 2 0 0 2 2 2 1 Tropomyosin like GLE1 PF07817.8 ETO24925.1 - 0.0036 16.2 0.6 0.0069 15.3 0.4 1.5 1 0 0 1 1 1 1 GLE1-like protein IncA PF04156.9 ETO24925.1 - 0.0086 15.6 4.7 0.0086 15.6 3.2 2.1 2 0 0 2 2 2 1 IncA protein HR1 PF02185.11 ETO24925.1 - 0.0089 15.7 5.5 0.012 15.2 2.2 2.5 2 0 0 2 2 2 1 Hr1 repeat NOZZLE PF08744.5 ETO24925.1 - 0.015 14.6 0.2 0.033 13.5 0.0 1.5 2 0 0 2 2 2 0 Plant transcription factor NOZZLE OmpH PF03938.9 ETO24925.1 - 0.033 14.1 2.5 0.073 12.9 1.7 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) V_ATPase_I PF01496.14 ETO24925.1 - 0.14 9.9 8.4 0.029 12.2 2.4 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF4140 PF13600.1 ETO24925.1 - 4.7 7.6 8.6 1.5 9.2 1.2 2.6 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) CCDC-167 PF15188.1 ETO24925.1 - 8.4 6.4 11.0 0.036 13.9 1.2 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 zf-RanBP PF00641.13 ETO24926.1 - 1.3e-07 30.5 27.1 0.0026 16.8 2.5 3.7 2 1 1 3 3 3 3 Zn-finger in Ran binding protein and others DZR PF12773.2 ETO24926.1 - 0.00033 20.3 22.1 0.0054 16.5 6.2 2.9 2 1 1 3 3 3 2 Double zinc ribbon DSPc PF00782.15 ETO24927.1 - 2.2e-20 72.6 0.7 4.2e-07 29.6 0.0 3.5 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain G-alpha PF00503.15 ETO24928.1 - 7.2e-16 57.8 0.2 9e-16 57.5 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Fig1 PF12351.3 ETO24929.1 - 1.1e-05 25.4 0.7 3.9e-05 23.6 0.3 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 TMF_DNA_bd PF12329.3 ETO24930.1 - 0.0054 16.5 23.7 0.0054 16.5 16.4 2.6 1 1 2 3 3 3 1 TATA element modulatory factor 1 DNA binding HD_4 PF13328.1 ETO24930.1 - 0.75 9.4 4.7 1 9.0 3.3 1.2 1 0 0 1 1 1 0 HD domain ALMT PF11744.3 ETO24930.1 - 3.3 6.2 10.2 4 5.9 7.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter ACCA PF03255.9 ETO24930.1 - 3.4 7.2 20.2 1.2 8.6 5.5 2.5 1 1 2 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit APG6 PF04111.7 ETO24930.1 - 5.5 5.9 22.7 6.8 5.6 15.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 PA26 PF04636.8 ETO24930.1 - 5.5 5.5 13.7 6.9 5.2 9.5 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Phage_GPO PF05929.6 ETO24930.1 - 7 5.8 16.2 14 4.8 10.8 1.5 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Peptidase_C6 PF00851.13 ETO24930.1 - 7.5 5.0 12.6 8 4.9 8.8 1.1 1 0 0 1 1 1 0 Helper component proteinase Vps4_C PF09336.5 ETO24931.1 - 1.5e-20 72.8 0.0 6.6e-20 70.7 0.0 1.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Chromo PF00385.19 ETO24932.1 - 9e-06 25.2 1.1 1.7e-05 24.3 0.7 1.6 1 1 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain YlbD_coat PF14071.1 ETO24932.1 - 2.2 8.3 6.4 0.56 10.2 0.1 2.0 1 1 1 2 2 2 0 Putative coat protein Zip PF02535.17 ETO24935.1 - 1.4e-05 24.3 0.0 1.7e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Ion_trans PF00520.26 ETO24935.1 - 0.00013 21.3 4.5 0.00013 21.3 3.1 1.9 2 0 0 2 2 2 1 Ion transport protein 7tm_1 PF00001.16 ETO24935.1 - 0.0041 16.2 2.2 0.0041 16.2 1.5 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) C2 PF00168.25 ETO24936.1 - 2.8e-11 43.1 0.4 2.8e-11 43.1 0.3 1.9 2 0 0 2 2 2 1 C2 domain CobT PF06213.7 ETO24937.1 - 2.6e-05 23.5 15.1 3.7e-05 23.0 10.5 1.2 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT DUF2457 PF10446.4 ETO24937.1 - 0.0046 15.7 23.9 0.0055 15.4 16.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) AATF-Che1 PF13339.1 ETO24937.1 - 0.0064 16.6 0.9 0.011 15.8 0.6 1.5 1 1 0 1 1 1 1 Apoptosis antagonizing transcription factor Nup54 PF13874.1 ETO24937.1 - 0.061 12.9 3.2 0.098 12.3 2.3 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 IncA PF04156.9 ETO24937.1 - 0.095 12.2 7.8 0.19 11.3 5.4 1.4 1 0 0 1 1 1 0 IncA protein CDC45 PF02724.9 ETO24937.1 - 0.1 10.6 15.9 0.12 10.4 11.1 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 ETO24937.1 - 0.33 10.1 20.0 0.5 9.5 13.9 1.3 1 1 0 1 1 1 0 SDA1 Zip PF02535.17 ETO24937.1 - 0.38 9.7 3.0 0.39 9.6 2.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter TRAP_alpha PF03896.11 ETO24937.1 - 3.6 6.5 12.2 5.4 5.9 8.5 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Astro_capsid PF03115.9 ETO24937.1 - 5.3 5.1 12.2 6 4.9 8.5 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor HR1 PF02185.11 ETO24937.1 - 5.9 6.7 10.0 2.8 7.7 2.9 2.3 1 1 1 2 2 2 0 Hr1 repeat SspB PF04386.8 ETO24937.1 - 8.1 6.0 10.0 17 4.9 6.9 1.6 1 0 0 1 1 1 0 Stringent starvation protein B YtzH PF14165.1 ETO24938.1 - 0.15 12.3 8.7 3.2 8.0 0.1 4.6 5 0 0 5 5 5 0 YtzH-like protein WD40 PF00400.27 ETO24939.1 - 8.3e-52 171.3 24.1 4.1e-10 39.1 0.0 6.9 8 0 0 8 8 8 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO24939.1 - 4.2e-08 31.7 0.5 0.82 7.7 0.0 4.7 1 1 3 4 4 4 4 Nucleoporin Nup120/160 DUF1900 PF08954.6 ETO24939.1 - 0.0071 15.8 0.1 1 8.9 0.0 3.1 3 1 0 3 3 3 1 Domain of unknown function (DUF1900) Peptidase_C48 PF02902.14 ETO24940.1 - 0.0075 15.9 0.0 0.0081 15.8 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Cation_efflux PF01545.16 ETO24941.1 - 1.4e-23 83.3 0.9 1.4e-23 83.3 0.7 1.6 2 0 0 2 2 2 1 Cation efflux family CDC45 PF02724.9 ETO24941.1 - 0.0011 17.1 3.6 0.0011 17.1 2.5 1.8 2 0 0 2 2 2 1 CDC45-like protein SAPS PF04499.10 ETO24941.1 - 0.018 13.7 0.0 0.018 13.7 0.0 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Mito_fiss_reg PF05308.6 ETO24941.1 - 0.02 14.2 15.7 0.035 13.4 10.9 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 ETO24941.1 - 0.91 8.7 13.2 1.6 7.9 9.2 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Pkinase PF00069.20 ETO24942.1 - 2.2e-66 223.6 0.0 2.4e-66 223.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO24942.1 - 4.7e-35 120.9 0.0 5.8e-35 120.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO24942.1 - 7.9e-05 21.7 0.0 0.00011 21.2 0.0 1.3 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 ETO24942.1 - 0.0085 15.4 0.3 0.48 9.7 0.0 2.1 2 0 0 2 2 2 2 PhoP regulatory network protein YrbL DUF778 PF05608.7 ETO24944.1 - 0.02 14.8 0.1 0.32 10.9 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF778) BTV_NS2 PF04514.7 ETO24944.1 - 1 8.1 15.9 1.4 7.7 11.0 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Pox_Ag35 PF03286.9 ETO24944.1 - 2.3 7.6 26.8 0.33 10.4 12.5 2.1 1 1 1 2 2 2 0 Pox virus Ag35 surface protein Astro_capsid PF03115.9 ETO24944.1 - 8.7 4.4 9.3 11 4.1 6.4 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor PAC2 PF09754.4 ETO24945.1 - 5.6e-07 29.6 0.1 0.017 15.0 0.0 3.2 2 2 0 2 2 2 2 PAC2 family HisKA_3 PF07730.8 ETO24945.1 - 0.089 13.1 0.2 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 Histidine kinase Tim54 PF11711.3 ETO24945.1 - 4.6 5.7 7.7 0.25 9.8 0.9 1.8 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 G-alpha PF00503.15 ETO24946.1 - 2.2e-16 59.5 0.5 2.5e-16 59.3 0.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit AAA_29 PF13555.1 ETO24946.1 - 0.0072 15.8 1.9 0.02 14.3 0.6 2.1 2 1 1 3 3 3 1 P-loop containing region of AAA domain Arf PF00025.16 ETO24946.1 - 0.0096 15.1 0.1 0.011 14.9 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family ABC_tran PF00005.22 ETO24946.1 - 0.099 12.9 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 ABC transporter G-alpha PF00503.15 ETO24947.1 - 5.2e-56 189.9 3.4 2.6e-42 144.8 0.7 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Arf PF00025.16 ETO24947.1 - 1.3e-05 24.5 0.1 3e-05 23.3 0.1 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family OST-HTH PF12872.2 ETO24948.1 - 3.9e-10 39.4 1.3 6.1e-05 22.7 0.0 4.8 4 0 0 4 4 4 3 OST-HTH/LOTUS domain RRM_1 PF00076.17 ETO24948.1 - 0.024 14.2 0.0 0.05 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DAGK_cat PF00781.19 ETO24949.1 - 2.2e-06 27.1 0.0 4.6e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.16 ETO24949.1 - 0.0074 15.0 0.0 0.01 14.6 0.0 1.4 1 1 0 1 1 1 1 ATP-NAD kinase Peptidase_C70 PF12385.3 ETO24949.1 - 0.022 14.4 0.1 0.26 10.9 0.0 2.0 1 1 1 2 2 2 0 Papain-like cysteine protease AvrRpt2 UCH PF00443.24 ETO24950.1 - 1.9e-26 92.7 14.2 1.9e-25 89.4 9.8 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SR-25 PF10500.4 ETO24950.1 - 0.0012 18.3 15.6 0.0019 17.7 10.8 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein HEPN PF05168.9 ETO24950.1 - 0.0065 16.3 0.3 0.47 10.3 0.0 2.9 2 1 1 3 3 3 1 HEPN domain Abhydrolase_9_N PF15420.1 ETO24951.1 - 0.41 10.3 9.1 1.5 8.4 6.3 2.0 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus DUF1517 PF07466.6 ETO24951.1 - 0.68 8.8 3.4 0.66 8.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) Ribosomal_L30_N PF08079.7 ETO24951.1 - 2 8.5 7.2 0.19 11.7 2.0 1.5 2 0 0 2 2 2 0 Ribosomal L30 N-terminal domain UPF0183 PF03676.9 ETO24952.1 - 3.4e-49 167.4 14.6 3.9e-24 84.9 0.0 4.6 3 1 0 3 3 3 3 Uncharacterised protein family (UPF0183) Zip PF02535.17 ETO24952.1 - 0.015 14.3 10.5 0.58 9.1 2.7 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter CobT PF06213.7 ETO24952.1 - 1.8 7.6 13.8 0.085 11.9 2.0 2.3 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DUF21 PF01595.15 ETO24953.1 - 3e-16 59.2 0.3 4e-16 58.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF21 SAM_MT PF04445.8 ETO24953.1 - 0.091 11.8 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase IncFII_repA PF02387.10 ETO24954.1 - 0.041 13.0 1.2 0.051 12.7 0.8 1.1 1 0 0 1 1 1 0 IncFII RepA protein family DUF3431 PF11913.3 ETO24954.1 - 0.058 12.8 0.3 0.091 12.2 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3431) EF-hand_6 PF13405.1 ETO24955.1 - 2.1e-09 36.4 4.1 0.048 13.5 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 ETO24955.1 - 4.4e-08 33.1 3.5 1.9e-06 27.9 0.5 2.8 2 2 1 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO24955.1 - 1.7e-06 26.9 2.3 0.08 12.2 0.1 4.0 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 ETO24955.1 - 0.0038 16.8 3.5 0.0087 15.6 0.4 2.8 2 1 0 2 2 2 1 EF-hand domain pair tRNA_lig_kinase PF08303.6 ETO24955.1 - 0.069 13.0 0.2 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 tRNA ligase kinase domain DUF2726 PF10881.3 ETO24955.1 - 0.081 12.5 0.1 0.3 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2726) Tn916-Xis PF09035.5 ETO24955.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Excisionase from transposon Tn916 DEP PF00610.16 ETO24956.1 - 9.4e-12 44.5 0.1 1.3e-11 44.0 0.1 1.2 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Pkinase PF00069.20 ETO24957.1 - 2.1e-06 27.1 6.2 5e-05 22.5 2.7 2.7 2 1 0 2 2 2 2 Protein kinase domain DUF823 PF05689.6 ETO24957.1 - 0.027 13.8 7.1 0.016 14.5 3.2 1.7 2 0 0 2 2 2 0 Salmonella repeat of unknown function (DUF823) RabGAP-TBC PF00566.13 ETO24957.1 - 7.7 5.9 7.3 15 5.0 5.1 1.5 1 1 0 1 1 1 0 Rab-GTPase-TBC domain DUF1777 PF08648.7 ETO24959.1 - 5.6e-05 22.9 37.3 0.0001 22.0 19.6 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF1777) Atrophin-1 PF03154.10 ETO24959.1 - 0.0002 19.7 11.6 0.0002 19.7 8.0 2.1 2 0 0 2 2 2 1 Atrophin-1 family TRP_2 PF08344.6 ETO24959.1 - 0.0087 15.9 0.4 1.2 9.0 0.0 2.6 2 0 0 2 2 2 2 Transient receptor ion channel II Tetraspannin PF00335.15 ETO24959.1 - 6.8 5.8 8.3 15 4.7 5.8 1.5 1 0 0 1 1 1 0 Tetraspanin family C1_1 PF00130.17 ETO24960.1 - 0.0096 15.6 0.8 0.0096 15.6 0.6 2.5 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 ETO24960.1 - 0.037 13.7 7.1 0.29 10.8 4.9 2.3 1 1 0 1 1 1 0 PHD-finger RNA_POL_M_15KD PF02150.11 ETO24960.1 - 0.078 12.6 0.1 0.078 12.6 0.1 2.9 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit Menin PF05053.8 ETO24960.1 - 5.4 5.0 12.7 7.5 4.5 8.8 1.1 1 0 0 1 1 1 0 Menin Mucin PF01456.12 ETO24962.1 - 0.0066 16.2 0.2 0.0066 16.2 0.2 2.5 3 0 0 3 3 3 1 Mucin-like glycoprotein EphA2_TM PF14575.1 ETO24962.1 - 0.23 11.8 0.9 16 5.9 0.0 3.2 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF3439 PF11921.3 ETO24962.1 - 1.3 8.8 8.4 2.5 7.8 5.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3439) Ribosomal_S4e PF00900.15 ETO24963.1 - 3.4e-13 49.0 0.0 3.4e-13 49.0 0.0 2.2 2 1 1 3 3 3 1 Ribosomal family S4e KOW PF00467.24 ETO24963.1 - 0.0018 17.8 3.3 0.0018 17.8 2.3 2.0 2 0 0 2 2 2 1 KOW motif DUF3816 PF12822.2 ETO24964.1 - 0.013 15.3 0.6 0.027 14.3 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) Adeno_E3_14_5 PF04834.7 ETO24964.1 - 0.056 13.8 0.4 0.056 13.8 0.3 2.1 2 1 0 2 2 2 0 Early E3 14.5 kDa protein S-antigen PF05756.6 ETO24964.1 - 0.057 13.3 2.9 0.81 9.7 0.1 2.4 2 0 0 2 2 2 0 S-antigen protein DUF1312 PF07009.6 ETO24964.1 - 0.21 11.4 4.6 1.2 8.9 0.4 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1312) DUF912 PF06024.7 ETO24964.1 - 1.1 9.3 6.6 1.2 9.2 3.4 2.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Med3 PF11593.3 ETO24965.1 - 0.051 12.8 49.6 0.059 12.6 34.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SOBP PF15279.1 ETO24965.1 - 7.2 6.9 18.8 8.5 6.6 13.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Tetraspannin PF00335.15 ETO24965.1 - 9.4 5.4 12.1 6.3 6.0 6.8 1.8 1 1 1 2 2 2 0 Tetraspanin family GtrA PF04138.9 ETO24967.1 - 4.1e-05 23.4 4.1 4.1e-05 23.4 2.8 2.6 2 1 0 2 2 2 1 GtrA-like protein Proteasome PF00227.21 ETO24968.1 - 2e-27 95.7 0.9 9.6e-27 93.4 0.6 1.8 1 1 0 1 1 1 1 Proteasome subunit Copper-fist PF00649.13 ETO24969.1 - 0.075 12.2 0.2 0.19 10.9 0.1 1.6 1 0 0 1 1 1 0 Copper fist DNA binding domain SAM_2 PF07647.12 ETO24970.1 - 0.0054 16.5 0.5 1.3 8.9 0.0 2.6 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO24970.1 - 0.017 15.3 0.7 0.21 11.8 0.5 2.3 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF506 PF04720.7 ETO24970.1 - 0.096 12.3 5.7 0.12 11.9 3.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF506) Suf PF05843.9 ETO24970.1 - 4.1 7.0 10.4 3.2 7.4 4.1 2.3 2 1 0 2 2 2 0 Suppressor of forked protein (Suf) CAP_GLY PF01302.20 ETO24973.1 - 0.00012 21.7 0.1 0.00025 20.6 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain MIS13 PF08202.6 ETO24973.1 - 0.0025 16.9 0.4 0.0036 16.4 0.3 1.2 1 0 0 1 1 1 1 Mis12-Mtw1 protein family GAS PF13851.1 ETO24973.1 - 0.012 14.8 1.9 0.02 14.1 1.3 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4201 PF13870.1 ETO24973.1 - 0.012 15.0 0.2 0.026 13.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF1515 PF07439.6 ETO24973.1 - 0.026 14.3 0.2 0.05 13.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF1342 PF07072.6 ETO24973.1 - 0.034 13.8 0.3 0.053 13.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1342) BTD PF09270.5 ETO24973.1 - 0.038 13.7 0.3 0.15 11.7 0.1 2.3 2 1 0 2 2 2 0 Beta-trefoil DNA-binding domain LOH1CR12 PF10158.4 ETO24973.1 - 0.045 13.5 0.3 0.081 12.7 0.2 1.5 1 0 0 1 1 1 0 Tumour suppressor protein ABC_tran_2 PF12848.2 ETO24973.1 - 0.057 13.2 1.0 0.11 12.3 0.7 1.4 1 0 0 1 1 1 0 ABC transporter CENP-F_leu_zip PF10473.4 ETO24973.1 - 0.064 13.1 0.7 0.13 12.1 0.5 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MAD PF05557.8 ETO24973.1 - 0.13 10.3 2.6 0.17 9.9 1.8 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DivIC PF04977.10 ETO24973.1 - 0.57 9.7 6.3 0.45 10.0 2.2 2.3 1 1 1 2 2 2 0 Septum formation initiator FlxA PF14282.1 ETO24973.1 - 1.5 8.8 9.0 6.7 6.7 6.2 2.1 1 1 0 1 1 1 0 FlxA-like protein ASD2 PF08687.6 ETO24974.1 - 0.62 9.3 9.2 2.4 7.3 0.3 2.2 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 DDE_Tnp_IS1595 PF12762.2 ETO24975.1 - 0.0006 19.6 0.5 0.0014 18.4 0.3 1.6 1 0 0 1 1 1 1 ISXO2-like transposase domain Lipocalin_6 PF13944.1 ETO24975.1 - 0.033 14.3 0.4 0.068 13.3 0.3 1.5 1 0 0 1 1 1 0 Lipocalin-like domain ComJ PF11033.3 ETO24975.1 - 0.062 12.9 1.4 0.87 9.2 0.0 2.6 1 1 1 2 2 2 0 Competence protein J (ComJ) Ant_C PF05586.6 ETO24975.1 - 0.065 13.6 0.1 0.63 10.5 0.0 2.4 1 1 1 2 2 2 0 Anthrax receptor C-terminus region Peptidase_C14 PF00656.17 ETO24978.1 - 7.1e-09 35.7 0.4 7.1e-09 35.7 0.3 2.0 2 0 0 2 2 2 1 Caspase domain Kelch_6 PF13964.1 ETO24978.1 - 4.8e-05 23.3 4.6 0.053 13.7 0.0 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 ETO24978.1 - 5.7e-05 23.1 0.0 0.0049 16.9 0.0 3.5 4 0 0 4 4 4 1 Galactose oxidase, central domain Caldesmon PF02029.10 ETO24978.1 - 0.00011 20.7 12.9 0.00017 20.1 8.9 1.2 1 0 0 1 1 1 1 Caldesmon Kelch_5 PF13854.1 ETO24978.1 - 0.00024 20.9 1.4 0.028 14.3 0.1 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETO24978.1 - 0.0027 17.4 1.7 0.073 12.8 0.1 3.2 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO24978.1 - 0.021 14.3 0.1 0.021 14.3 0.1 3.9 5 0 0 5 5 5 0 Kelch motif Kelch_2 PF07646.10 ETO24978.1 - 0.36 10.6 3.5 1 9.2 0.0 3.6 4 0 0 4 4 4 0 Kelch motif Peptidase_C14 PF00656.17 ETO24979.1 - 1.3e-09 38.1 0.6 3.4e-09 36.7 0.4 1.7 1 1 0 1 1 1 1 Caspase domain CAAP1 PF15335.1 ETO24979.1 - 4.3 7.6 8.5 0.5 10.5 0.2 3.1 3 1 0 3 3 3 0 Caspase activity and apoptosis inhibitor 1 Microvir_H PF04687.7 ETO24980.1 - 0.059 12.3 0.9 0.08 11.9 0.6 1.2 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) G-patch_2 PF12656.2 ETO24980.1 - 0.21 11.4 0.1 0.21 11.4 0.1 2.2 2 1 0 2 2 2 0 DExH-box splicing factor binding site Myb_DNA-bind_4 PF13837.1 ETO24980.1 - 0.61 10.2 9.1 1.9 8.6 6.2 2.0 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain PAG PF15347.1 ETO24981.1 - 0.056 12.5 0.0 0.15 11.1 0.0 1.5 2 0 0 2 2 2 0 Phosphoprotein associated with glycosphingolipid-enriched GvpL_GvpF PF06386.6 ETO24982.1 - 0.051 13.1 0.0 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF4411 PF14367.1 ETO24982.1 - 0.087 12.5 0.0 8.7 6.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4411) SIP1 PF04938.7 ETO24983.1 - 0.07 12.4 1.5 0.076 12.3 1.1 1.1 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF521 PF04412.8 ETO24983.1 - 0.079 11.5 0.1 0.091 11.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF521) G-alpha PF00503.15 ETO24984.1 - 0.063 11.9 1.5 0.071 11.7 1.0 1.0 1 0 0 1 1 1 0 G-protein alpha subunit PBP1_TM PF14812.1 ETO24985.1 - 0.0047 17.2 5.2 0.011 15.9 0.9 2.3 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 ETO24985.1 - 0.054 13.0 6.2 0.024 14.1 1.4 2.1 2 0 0 2 2 2 0 Nucleoplasmin DUF3245 PF11595.3 ETO24985.1 - 0.67 10.2 9.7 0.24 11.6 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) DUF4611 PF15387.1 ETO24985.1 - 7.6 6.7 10.8 6.1 7.0 2.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF3246 PF11596.3 ETO24985.1 - 9.6 5.4 9.1 0.54 9.5 2.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3246) peroxidase PF00141.18 ETO24986.1 - 1.6e-19 70.3 0.0 1.8e-19 70.1 0.0 1.0 1 0 0 1 1 1 1 Peroxidase peroxidase PF00141.18 ETO24987.1 - 2.6e-10 40.1 0.0 3.9e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Peroxidase GBP_repeat PF02526.9 ETO24987.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycophorin-binding protein Methyltransf_9 PF08003.6 ETO24988.1 - 0.97 8.0 8.9 0.08 11.6 2.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1698) TRAM_LAG1_CLN8 PF03798.11 ETO24989.1 - 1.2e-11 44.5 21.6 2.6e-11 43.4 14.9 1.6 1 1 0 1 1 1 1 TLC domain CAP_GLY PF01302.20 ETO24991.1 - 1.8e-31 107.6 3.9 6.6e-16 57.7 0.1 2.1 2 0 0 2 2 2 2 CAP-Gly domain Peptidase_M4_C PF02868.10 ETO24991.1 - 0.029 14.1 0.1 0.063 13.0 0.0 1.5 1 1 1 2 2 2 0 Thermolysin metallopeptidase, alpha-helical domain AAA PF00004.24 ETO24992.1 - 0.013 15.7 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 ETO24992.1 - 0.025 15.4 0.0 0.042 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain SKI PF01202.17 ETO24992.1 - 0.077 12.8 0.0 0.16 11.8 0.0 1.5 1 1 0 1 1 1 0 Shikimate kinase Cass2 PF14526.1 ETO24992.1 - 0.086 12.8 0.1 1.2 9.1 0.1 2.1 1 1 1 2 2 2 0 Integron-associated effector binding protein WEMBL PF05701.6 ETO24996.1 - 0.00076 18.0 6.6 0.00094 17.7 4.6 1.0 1 0 0 1 1 1 1 Weak chloroplast movement under blue light FTA4 PF13093.1 ETO24996.1 - 0.0025 17.2 1.8 0.0026 17.2 1.2 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 ERM PF00769.14 ETO24996.1 - 0.0027 17.3 3.9 0.0031 17.0 2.7 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Phage_GP20 PF06810.6 ETO24996.1 - 0.0045 16.4 4.6 0.0045 16.4 3.2 1.5 2 0 0 2 2 2 1 Phage minor structural protein GP20 ASD2 PF08687.6 ETO24996.1 - 0.0055 16.0 1.8 0.0067 15.7 1.2 1.1 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 Filament PF00038.16 ETO24996.1 - 0.0071 15.8 5.8 0.009 15.5 4.0 1.1 1 0 0 1 1 1 1 Intermediate filament protein Prefoldin_2 PF01920.15 ETO24996.1 - 0.008 15.9 4.6 0.013 15.2 3.2 1.4 1 0 0 1 1 1 1 Prefoldin subunit IFT57 PF10498.4 ETO24996.1 - 0.009 14.7 5.7 0.011 14.4 4.0 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 GAS PF13851.1 ETO24996.1 - 0.0092 15.1 5.3 0.012 14.7 3.6 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding FH2 PF02181.18 ETO24996.1 - 0.01 14.7 0.4 0.012 14.5 0.3 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain DUF607 PF04678.8 ETO24996.1 - 0.012 15.5 1.5 0.014 15.2 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF607 CENP-F_leu_zip PF10473.4 ETO24996.1 - 0.013 15.4 5.5 0.017 15.0 3.8 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_27 PF13514.1 ETO24996.1 - 0.013 13.2 3.9 0.016 12.9 2.7 1.0 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 ETO24996.1 - 0.016 12.5 4.2 0.019 12.3 2.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TBPIP PF07106.8 ETO24996.1 - 0.017 14.6 4.8 0.034 13.7 3.3 1.5 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Jnk-SapK_ap_N PF09744.4 ETO24996.1 - 0.018 15.0 1.8 0.023 14.7 1.3 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Mnd1 PF03962.10 ETO24996.1 - 0.028 14.0 2.8 0.036 13.7 1.9 1.2 1 0 0 1 1 1 0 Mnd1 family V_ATPase_I PF01496.14 ETO24996.1 - 0.031 12.1 0.6 0.031 12.1 0.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATG16 PF08614.6 ETO24996.1 - 0.033 13.9 6.5 0.042 13.6 4.5 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) RVT_3 PF13456.1 ETO24996.1 - 0.033 13.9 1.9 0.051 13.3 1.3 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like APG6 PF04111.7 ETO24996.1 - 0.034 13.1 4.2 0.04 12.9 2.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Spc7 PF08317.6 ETO24996.1 - 0.042 12.5 4.3 0.049 12.3 3.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ACCA PF03255.9 ETO24996.1 - 0.061 12.8 1.3 0.09 12.3 0.9 1.3 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF4407 PF14362.1 ETO24996.1 - 0.07 12.0 2.8 0.082 11.8 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Vps5 PF09325.5 ETO24996.1 - 0.076 12.2 6.1 0.1 11.8 4.2 1.1 1 0 0 1 1 1 0 Vps5 C terminal like DUF2400 PF09674.5 ETO24996.1 - 0.08 12.6 0.3 0.089 12.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF342 PF03961.8 ETO24996.1 - 0.099 11.0 2.7 0.11 10.9 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) HR1 PF02185.11 ETO24996.1 - 0.12 12.1 8.7 0.23 11.2 6.0 1.6 1 1 0 1 1 1 0 Hr1 repeat Viral_P18 PF04521.8 ETO24996.1 - 0.12 11.8 6.5 0.19 11.2 3.9 1.6 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DUF2968 PF11180.3 ETO24996.1 - 0.13 11.6 10.1 0.17 11.2 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF972 PF06156.8 ETO24996.1 - 0.14 12.4 4.2 0.22 11.8 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Nup54 PF13874.1 ETO24996.1 - 0.17 11.5 7.7 0.12 12.0 4.0 1.6 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 COG2 PF06148.6 ETO24996.1 - 0.22 11.3 3.3 0.51 10.1 2.0 1.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 EAP30 PF04157.11 ETO24996.1 - 0.31 10.1 3.6 0.42 9.7 2.5 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family IncA PF04156.9 ETO24996.1 - 0.39 10.2 7.1 0.5 9.9 4.9 1.2 1 0 0 1 1 1 0 IncA protein FemAB PF02388.11 ETO24996.1 - 0.39 9.3 5.5 0.49 9.0 3.8 1.1 1 0 0 1 1 1 0 FemAB family TMF_TATA_bd PF12325.3 ETO24996.1 - 0.76 9.5 10.1 12 5.6 7.1 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding OmpH PF03938.9 ETO24996.1 - 0.96 9.3 8.9 1.3 8.9 6.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TMPIT PF07851.8 ETO24996.1 - 1.1 8.2 5.8 1.6 7.7 4.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF2361 PF10153.4 ETO24996.1 - 1.6 8.9 7.4 2.1 8.5 5.0 1.4 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) Syntaxin PF00804.20 ETO24996.1 - 2.6 8.2 8.4 7.7 6.7 5.8 1.8 1 1 0 1 1 1 0 Syntaxin Spc24 PF08286.6 ETO24996.1 - 5.5 6.7 8.8 19 4.9 5.7 2.1 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Alba PF01918.16 ETO24997.1 - 2.1e-10 40.0 0.1 3.4e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 Alba Rpp20 PF12328.3 ETO24997.1 - 0.039 13.6 0.3 0.065 12.8 0.2 1.3 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Laminin_N PF00055.12 ETO24998.1 - 1.6 7.6 8.9 3.2 6.6 6.1 1.6 1 1 0 1 1 1 0 Laminin N-terminal (Domain VI) zf-CCHC_5 PF14787.1 ETO24998.1 - 4.3 6.9 9.9 0.3 10.5 2.4 2.2 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger BTV_NS2 PF04514.7 ETO25000.1 - 9.2 5.0 12.7 12 4.7 8.8 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Kelch_1 PF01344.20 ETO25001.1 - 3.5e-13 48.8 4.3 0.0066 15.9 0.0 5.8 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.1 ETO25001.1 - 0.0004 20.1 3.3 0.69 9.7 0.0 5.0 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO25001.1 - 0.00089 19.3 11.7 1.4 9.2 0.1 6.5 6 2 1 7 7 7 3 Kelch motif ATG27 PF09451.5 ETO25002.1 - 2.4 7.3 12.5 4.4 6.4 8.6 1.4 1 0 0 1 1 1 0 Autophagy-related protein 27 Slx4 PF09494.5 ETO25004.1 - 1.1e-06 28.3 0.1 1.8e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 Slx4 endonuclease TPR_12 PF13424.1 ETO25005.1 - 2.9e-06 27.1 1.9 0.013 15.4 0.3 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO25005.1 - 5.7e-05 22.6 2.8 0.0034 16.9 0.7 2.4 1 1 1 2 2 2 2 TPR repeat TPR_7 PF13176.1 ETO25005.1 - 0.00018 21.0 2.8 4.5 7.2 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat Prefoldin PF02996.12 ETO25005.1 - 0.0052 16.4 0.5 0.037 13.6 0.1 2.3 1 1 1 2 2 2 1 Prefoldin subunit TPR_1 PF00515.23 ETO25005.1 - 0.022 14.3 7.8 1.3 8.7 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Mcm10 PF09332.6 ETO25005.1 - 0.054 12.8 1.7 0.14 11.5 0.2 1.9 2 0 0 2 2 2 0 Mcm10 replication factor Apc3 PF12895.2 ETO25005.1 - 0.057 13.5 2.4 0.078 13.1 0.4 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Methyltransf_12 PF08242.7 ETO25006.1 - 0.0013 19.1 0.5 0.0016 18.8 0.3 1.2 1 0 0 1 1 1 1 Methyltransferase domain Menin PF05053.8 ETO25006.1 - 0.44 8.6 3.2 0.49 8.5 2.2 1.1 1 0 0 1 1 1 0 Menin DUF383 PF04063.9 ETO25007.1 - 2.6e-08 33.6 0.1 8.8e-07 28.6 0.1 3.0 1 1 0 1 1 1 1 Domain of unknown function (DUF383) HEAT PF02985.17 ETO25007.1 - 0.021 14.8 0.4 22 5.4 0.0 3.7 4 0 0 4 4 4 0 HEAT repeat Arm PF00514.18 ETO25007.1 - 0.044 13.6 0.1 0.15 11.9 0.1 2.0 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 ETO25007.1 - 0.14 12.4 0.0 0.46 10.7 0.0 1.8 1 1 0 1 1 1 0 HEAT repeats DUF4578 PF15147.1 ETO25008.1 - 0.0089 16.4 0.9 0.012 15.9 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4578) DUF916 PF06030.7 ETO25008.1 - 0.25 11.1 0.1 0.25 11.1 0.1 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF916) Mucin PF01456.12 ETO25008.1 - 1.5 8.6 16.4 4.6 6.9 10.8 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein Dicty_REP PF05086.7 ETO25008.1 - 2.7 5.6 13.5 3 5.4 9.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Neurochondrin PF05536.6 ETO25009.1 - 0.00036 19.0 0.2 0.00058 18.3 0.1 1.3 1 0 0 1 1 1 1 Neurochondrin AAA_26 PF13500.1 ETO25009.1 - 0.0063 16.1 0.1 3.3 7.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain Mcp5_PH PF12814.2 ETO25009.1 - 0.063 13.1 0.1 0.42 10.5 0.0 2.1 1 1 1 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology DNA_pol_B PF00136.16 ETO25010.1 - 1.4e-22 80.1 0.0 3.8e-22 78.7 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 ETO25010.1 - 7.2e-14 51.3 0.0 1.2e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain ABC2_membrane_3 PF12698.2 ETO25010.1 - 0.068 12.2 0.0 0.068 12.2 0.0 1.4 2 0 0 2 2 2 0 ABC-2 family transporter protein FixQ PF05545.6 ETO25010.1 - 0.12 12.0 0.1 0.12 12.0 0.1 2.3 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF3021 PF11457.3 ETO25010.1 - 0.14 12.0 3.5 0.33 10.8 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) Chlam_OMP3 PF03503.8 ETO25012.1 - 0.12 12.5 0.6 0.22 11.7 0.4 1.3 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 3 LMBR1 PF04791.11 ETO25013.1 - 4.4e-20 71.7 6.5 1.4e-09 37.0 0.1 3.7 3 1 0 3 3 3 2 LMBR1-like membrane protein Nop14 PF04147.7 ETO25013.1 - 0.0041 15.1 24.5 0.0066 14.4 17.0 1.3 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 ETO25013.1 - 0.014 13.9 23.9 0.02 13.3 16.6 1.3 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 ETO25013.1 - 0.71 7.8 32.2 1.3 6.9 22.3 1.4 1 0 0 1 1 1 0 CDC45-like protein DUF1152 PF06626.7 ETO25014.1 - 3.1e-10 39.6 0.0 8.3e-07 28.4 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1152) Rad51 PF08423.6 ETO25015.1 - 1.6e-19 69.8 0.4 2.1e-18 66.1 0.1 2.1 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.1 ETO25015.1 - 3.1e-13 49.5 0.0 2.8e-11 43.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 ETO25015.1 - 6.7e-10 38.4 0.5 2.6e-09 36.5 0.1 2.1 1 1 1 2 2 2 1 KaiC AAA_22 PF13401.1 ETO25015.1 - 1.6e-05 25.0 0.4 0.0001 22.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain RecA PF00154.16 ETO25015.1 - 0.00027 20.1 0.0 0.2 10.6 0.0 3.0 3 0 0 3 3 3 1 recA bacterial DNA recombination protein DUF2075 PF09848.4 ETO25015.1 - 0.004 16.1 1.9 0.029 13.3 0.1 2.4 1 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DUF1666 PF07891.7 ETO25015.1 - 0.0093 15.4 1.6 0.016 14.6 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1666) Polysacc_synt_2 PF02719.10 ETO25015.1 - 0.021 13.7 0.2 0.038 12.8 0.1 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein AAA_18 PF13238.1 ETO25015.1 - 0.024 14.9 3.5 0.042 14.1 0.1 2.8 2 2 0 2 2 2 0 AAA domain AAA_16 PF13191.1 ETO25015.1 - 0.029 14.3 0.0 0.075 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 ETO25015.1 - 0.061 12.9 0.1 0.2 11.3 0.1 1.8 1 1 0 1 1 1 0 NACHT domain AAA PF00004.24 ETO25015.1 - 0.083 13.0 1.4 1.1 9.4 0.3 2.5 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 ETO25015.1 - 0.14 13.0 0.5 15 6.3 0.1 2.9 2 1 0 2 2 2 0 AAA domain CbiA PF01656.18 ETO25015.1 - 0.15 11.4 1.5 3.5 6.9 0.8 2.7 1 1 1 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF4407 PF14362.1 ETO25015.1 - 0.22 10.4 1.2 0.34 9.8 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_5 PF07728.9 ETO25015.1 - 0.52 10.0 3.0 0.45 10.2 0.1 2.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF3439 PF11921.3 ETO25015.1 - 1.6 8.5 4.3 2.5 7.8 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) Mucin PF01456.12 ETO25015.1 - 5.9 6.6 10.3 9.9 5.9 7.1 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Kelch_6 PF13964.1 ETO25017.1 - 6.7e-05 22.8 1.8 0.027 14.6 0.2 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 ETO25017.1 - 0.031 13.8 7.4 1.1 8.9 0.2 4.2 4 1 0 4 4 4 0 Kelch motif Kelch_2 PF07646.10 ETO25017.1 - 0.55 10.0 6.5 4.1 7.3 0.1 4.1 4 1 0 4 4 4 0 Kelch motif SIN1 PF05422.7 ETO25018.1 - 0.00088 17.9 1.2 0.0012 17.4 0.1 1.7 1 1 1 2 2 2 1 Stress-activated map kinase interacting protein 1 (SIN1) DSPc PF00782.15 ETO25019.1 - 6.1e-23 80.8 0.1 7.1e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 ETO25019.1 - 0.019 14.3 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 ETO25019.1 - 0.052 13.8 0.0 1 9.5 0.0 2.1 1 1 0 2 2 2 0 Tyrosine phosphatase family Init_tRNA_PT PF04179.7 ETO25019.1 - 0.095 11.5 0.1 0.1 11.4 0.1 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Vpu PF00558.14 ETO25020.1 - 0.042 13.4 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 Vpu protein Alveol-reg_P311 PF11092.3 ETO25021.1 - 0.16 11.9 0.5 10 6.1 0.0 2.8 2 1 1 3 3 3 0 Neuronal protein 3.1 (p311) COG6 PF06419.6 ETO25023.1 - 9e-20 70.3 16.8 1.3e-18 66.4 11.7 2.1 1 1 0 1 1 1 1 Conserved oligomeric complex COG6 Dak2 PF02734.12 ETO25023.1 - 0.0043 16.7 0.2 0.0076 15.9 0.2 1.4 1 0 0 1 1 1 1 DAK2 domain V_ATPase_I PF01496.14 ETO25023.1 - 0.0094 13.8 6.8 0.01 13.7 4.7 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF4239 PF14023.1 ETO25023.1 - 0.088 12.1 3.8 0.11 11.8 1.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) YflT PF11181.3 ETO25023.1 - 0.28 11.3 8.4 0.085 13.0 2.4 2.4 1 1 1 2 2 2 0 Heat induced stress protein YflT DUF2533 PF10752.4 ETO25023.1 - 0.49 10.7 5.1 1.2 9.4 3.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) Peptidase_C6 PF00851.13 ETO25023.1 - 0.51 8.9 9.6 0.35 9.4 5.0 1.8 1 1 1 2 2 2 0 Helper component proteinase DUF948 PF06103.6 ETO25023.1 - 0.68 9.8 5.6 0.24 11.3 1.6 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Sec20 PF03908.8 ETO25023.1 - 3.6 7.3 7.7 3.1 7.5 2.3 2.5 2 0 0 2 2 2 0 Sec20 XRN_N PF03159.13 ETO25024.1 - 1.8e-38 132.2 0.8 4e-38 131.1 0.0 1.8 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus phiKZ_IP PF12699.2 ETO25024.1 - 0.12 11.3 1.8 0.15 10.9 1.2 1.1 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins Secretin_N_2 PF07655.8 ETO25024.1 - 1.3 9.4 13.2 4.6 7.7 8.5 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain RabGAP-TBC PF00566.13 ETO25025.1 - 1.1e-10 41.3 0.5 7.4e-08 32.1 0.4 2.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain TLD PF07534.11 ETO25025.1 - 0.00038 20.4 0.0 0.0011 19.0 0.0 1.8 1 0 0 1 1 1 1 TLD SPX PF03105.14 ETO25026.1 - 0.063 13.0 17.3 0.085 12.6 12.0 1.2 1 0 0 1 1 1 0 SPX domain DUF2413 PF10310.4 ETO25026.1 - 0.093 11.5 16.1 0.12 11.2 11.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Nop14 PF04147.7 ETO25026.1 - 0.96 7.2 22.9 1.2 6.9 15.9 1.2 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 ETO25026.1 - 1.2 8.3 14.7 1.5 7.9 10.2 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF913 PF06025.7 ETO25026.1 - 5.1 5.7 7.6 4.3 6.0 4.3 1.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2457 PF10446.4 ETO25026.1 - 6.1 5.4 27.4 1.1 7.9 16.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) DUF2868 PF11067.3 ETO25026.1 - 8.3 5.4 6.3 4.2 6.4 3.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) CRAL_TRIO PF00650.15 ETO25027.1 - 1.9e-14 53.4 0.8 1.7e-13 50.4 0.1 2.6 3 1 0 3 3 3 1 CRAL/TRIO domain DUF1675 PF07897.6 ETO25027.1 - 0.35 10.6 11.6 0.56 10.0 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Tim54 PF11711.3 ETO25028.1 - 0.53 8.8 4.5 1.1 7.8 3.1 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Polyoma_coat PF00718.15 ETO25029.1 - 0.097 11.5 0.1 0.14 11.0 0.1 1.2 1 0 0 1 1 1 0 Polyomavirus coat protein WD40 PF00400.27 ETO25030.1 - 3.3e-10 39.4 27.4 1.4e-08 34.3 0.1 5.2 4 1 0 4 4 4 3 WD domain, G-beta repeat FYDLN_acid PF09538.5 ETO25030.1 - 1.6 9.3 16.7 9.4 6.8 4.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) PH PF00169.24 ETO25031.1 - 3.1e-09 36.9 0.9 0.0016 18.5 0.1 3.3 2 1 1 3 3 3 2 PH domain Exo_endo_phos_2 PF14529.1 ETO25032.1 - 1.9e-06 27.4 1.7 9.7e-06 25.1 0.1 2.5 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase ASD2 PF08687.6 ETO25032.1 - 0.065 12.5 0.1 0.13 11.5 0.1 1.5 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 zf-C2H2_4 PF13894.1 ETO25033.1 - 5.2 7.6 10.6 4.1 7.9 5.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger CAP_GLY PF01302.20 ETO25035.1 - 0.13 11.9 0.2 3.9 7.2 0.0 2.2 2 0 0 2 2 2 0 CAP-Gly domain SpoIISA_toxin PF14171.1 ETO25036.1 - 0.028 13.6 0.3 0.034 13.4 0.2 1.1 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system DUF2873 PF11395.3 ETO25036.1 - 0.49 9.9 4.5 0.24 11.0 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2873) GST_N_3 PF13417.1 ETO25037.1 - 1.9e-18 66.4 0.0 3.7e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETO25037.1 - 4.6e-13 48.9 0.0 8.8e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 ETO25037.1 - 7.5e-10 38.8 0.0 1.5e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 ETO25037.1 - 0.00027 20.7 0.0 0.00049 19.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 ETO25037.1 - 0.099 12.6 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ANAPC15 PF15243.1 ETO25038.1 - 0.03 14.3 6.9 0.036 14.1 4.8 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 PspB PF06667.7 ETO25038.1 - 0.035 14.0 1.2 0.048 13.6 0.9 1.2 1 0 0 1 1 1 0 Phage shock protein B TMCO5 PF14992.1 ETO25038.1 - 0.14 11.2 8.5 0.15 11.1 5.9 1.0 1 0 0 1 1 1 0 TMCO5 family PBP_sp32 PF07222.7 ETO25038.1 - 3.7 6.6 9.9 3.7 6.6 6.9 1.0 1 0 0 1 1 1 0 Proacrosin binding protein sp32 TLD PF07534.11 ETO25039.1 - 3.9e-09 36.6 2.3 3.9e-07 30.1 0.0 2.8 3 0 0 3 3 3 2 TLD HD-ZIP_N PF04618.7 ETO25039.1 - 0.021 15.3 1.9 0.021 15.3 1.3 3.2 3 1 0 3 3 3 0 HD-ZIP protein N terminus Apis_Csd PF11671.3 ETO25039.1 - 0.41 10.4 15.5 0.055 13.2 2.0 2.4 2 0 0 2 2 2 0 Complementary sex determiner protein NDK PF00334.14 ETO25040.1 - 1.4e-85 283.9 0.0 4.2e-43 146.3 0.0 2.0 1 1 1 2 2 2 2 Nucleoside diphosphate kinase LMP PF04778.7 ETO25040.1 - 0.025 14.3 0.2 5.5 6.7 0.0 2.3 2 0 0 2 2 2 0 LMP repeated region Arg_repressor PF01316.16 ETO25040.1 - 0.084 12.4 0.3 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Arginine repressor, DNA binding domain Pkinase PF00069.20 ETO25041.1 - 1.8e-42 145.3 0.0 2.1e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO25041.1 - 1.1e-18 67.2 0.0 1.9e-18 66.4 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase MFS_1 PF07690.11 ETO25042.1 - 3.4e-28 98.3 31.6 5.9e-19 67.9 12.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 ETO25042.1 - 6e-06 24.6 9.4 1.4e-05 23.4 6.5 1.6 1 1 0 1 1 1 1 Transmembrane secretion effector ATG22 PF11700.3 ETO25042.1 - 8.4e-06 24.5 11.7 1.2e-05 24.0 8.1 1.2 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Sugar_tr PF00083.19 ETO25042.1 - 7.8e-05 21.4 9.4 7.8e-05 21.4 6.5 2.8 1 1 3 4 4 4 1 Sugar (and other) transporter LacY_symp PF01306.14 ETO25042.1 - 0.00068 18.3 4.1 0.0011 17.6 1.6 1.9 2 0 0 2 2 2 1 LacY proton/sugar symporter UNC-93 PF05978.11 ETO25042.1 - 0.0032 16.9 4.8 0.021 14.3 1.1 2.5 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 OATP PF03137.15 ETO25042.1 - 0.012 13.7 2.5 0.023 12.7 0.0 2.4 2 2 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Methyltransf_21 PF05050.7 ETO25043.1 - 2.5e-08 34.0 0.8 4.3e-08 33.2 0.5 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain YjgP_YjgQ PF03739.9 ETO25043.1 - 0.0069 15.1 0.5 0.0069 15.1 0.4 1.4 2 0 0 2 2 2 1 Predicted permease YjgP/YjgQ family DUF1837 PF08878.6 ETO25043.1 - 0.0096 15.5 7.9 0.0096 15.5 5.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1837) Rxt3 PF08642.5 ETO25043.1 - 0.16 12.1 2.5 1.2 9.4 0.1 2.5 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 BLVR PF06375.6 ETO25043.1 - 0.25 11.1 13.0 0.52 10.1 0.9 2.3 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Cupin_4 PF08007.7 ETO25044.1 - 9.3e-09 34.9 4.8 1.1e-05 24.8 0.0 3.9 4 0 0 4 4 4 3 Cupin superfamily protein GlcNAc PF11397.3 ETO25045.1 - 1.3e-17 63.9 0.2 2.3e-14 53.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase (GlcNAc) DUF1068 PF06364.7 ETO25046.1 - 0.033 13.7 1.5 0.059 12.9 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) Peptidase_M3_N PF08439.5 ETO25046.1 - 0.045 13.8 0.9 0.092 12.8 0.6 1.5 1 0 0 1 1 1 0 Oligopeptidase F SufE PF02657.10 ETO25046.1 - 0.35 10.4 4.9 0.67 9.5 0.6 2.4 1 1 1 2 2 2 0 Fe-S metabolism associated domain bPH_3 PF14470.1 ETO25047.1 - 0.048 13.9 1.6 0.39 10.9 0.1 2.3 1 1 1 2 2 2 0 Bacterial PH domain SICA_beta PF12878.2 ETO25047.1 - 0.083 12.6 5.3 0.88 9.3 3.7 2.1 1 1 0 1 1 1 0 SICA extracellular beta domain Med19 PF10278.4 ETO25047.1 - 0.65 9.6 9.5 0.8 9.3 5.7 1.6 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Arm PF00514.18 ETO25048.1 - 1.4e-05 24.7 0.2 0.07 12.9 0.0 3.4 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat DUF4359 PF14271.1 ETO25048.1 - 0.096 13.0 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4359) Ank_4 PF13637.1 ETO25049.1 - 3.3e-09 37.0 0.1 1.6e-06 28.4 0.0 2.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO25049.1 - 4.2e-09 36.6 0.1 9e-09 35.5 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO25049.1 - 5.4e-07 29.6 0.1 1.2e-05 25.3 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO25049.1 - 0.00028 20.8 0.1 2.5 8.6 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 ETO25049.1 - 0.00029 20.4 0.1 0.092 12.5 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat AhpC-TSA PF00578.16 ETO25049.1 - 0.011 15.4 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family EntA_Immun PF08951.5 ETO25049.1 - 0.025 14.7 1.2 5 7.3 0.2 2.5 2 0 0 2 2 2 0 Enterocin A Immunity ACDC PF14733.1 ETO25049.1 - 0.046 13.8 1.0 0.1 12.7 0.2 2.0 1 1 1 2 2 2 0 AP2-coincident C-terminal DUF3447 PF11929.3 ETO25049.1 - 0.8 9.5 8.9 0.22 11.3 1.0 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF3447) SOR_SNZ PF01680.12 ETO25050.1 - 0.00036 20.1 1.2 0.00062 19.4 0.8 1.6 1 0 0 1 1 1 1 SOR/SNZ family DUF948 PF06103.6 ETO25050.1 - 0.011 15.5 4.9 0.011 15.5 3.4 3.8 2 1 2 4 4 3 0 Bacterial protein of unknown function (DUF948) DUF1129 PF06570.6 ETO25050.1 - 0.015 14.6 0.1 0.015 14.6 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) ISG65-75 PF11727.3 ETO25050.1 - 0.023 13.7 7.9 0.3 10.1 1.1 2.2 1 1 1 2 2 2 0 Invariant surface glycoprotein PspA_IM30 PF04012.7 ETO25050.1 - 0.03 13.6 0.8 0.055 12.8 0.5 1.4 1 0 0 1 1 1 0 PspA/IM30 family DUF3829 PF12889.2 ETO25050.1 - 0.036 13.2 0.4 0.15 11.2 0.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3829) DUF812 PF05667.6 ETO25050.1 - 0.053 12.0 2.6 0.071 11.6 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF3139 PF11337.3 ETO25050.1 - 0.07 13.4 0.4 0.25 11.6 0.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3139) DUF2231 PF09990.4 ETO25050.1 - 0.072 13.4 0.1 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) PhageMin_Tail PF10145.4 ETO25050.1 - 0.09 12.4 1.8 0.53 9.9 1.2 2.1 1 1 1 2 2 2 0 Phage-related minor tail protein HN PF00423.14 ETO25050.1 - 0.092 11.0 1.3 0.15 10.3 0.9 1.3 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase MCPsignal PF00015.16 ETO25050.1 - 0.2 11.1 18.5 0.91 9.0 11.5 2.2 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain HisKA_3 PF07730.8 ETO25050.1 - 0.41 11.0 2.4 8.2 6.8 0.2 2.9 1 1 1 2 2 2 0 Histidine kinase DASH_Duo1 PF08651.5 ETO25050.1 - 0.43 10.1 2.8 2.5 7.7 0.1 3.1 3 1 1 4 4 4 0 DASH complex subunit Duo1 COG2 PF06148.6 ETO25050.1 - 0.44 10.4 4.8 2.4 8.0 0.4 2.9 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 V_ATPase_I PF01496.14 ETO25050.1 - 0.69 7.6 3.4 0.44 8.3 0.9 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF848 PF05852.6 ETO25050.1 - 1.1 9.0 5.0 0.52 10.1 0.8 2.2 1 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) APG17 PF04108.7 ETO25050.1 - 1.5 7.5 5.9 16 4.1 4.0 2.2 1 1 0 1 1 1 0 Autophagy protein Apg17 Laminin_I PF06008.9 ETO25050.1 - 1.5 8.0 4.8 1.9 7.7 1.9 1.9 1 1 1 2 2 2 0 Laminin Domain I Syntaxin-6_N PF09177.6 ETO25050.1 - 1.8 9.0 6.4 0.41 11.0 0.4 2.8 3 1 0 3 3 3 0 Syntaxin 6, N-terminal DUF745 PF05335.8 ETO25050.1 - 1.9 8.0 10.5 3.8 6.9 6.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Reo_sigmaC PF04582.7 ETO25050.1 - 2.8 7.0 7.6 0.7 9.0 0.8 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Laminin_II PF06009.7 ETO25050.1 - 3.9 7.2 11.9 1.4 8.6 1.1 3.0 2 1 1 3 3 3 0 Laminin Domain II PAXIP1_C PF15364.1 ETO25051.1 - 0.0053 16.6 1.8 0.0066 16.3 1.3 1.1 1 0 0 1 1 1 1 PAXIP1-associated-protein-1 C term PTIP binding protein EcoRI_methylase PF13651.1 ETO25051.1 - 0.01 14.9 6.2 0.01 14.9 3.7 1.4 2 0 0 2 2 2 0 Adenine-specific methyltransferase EcoRI Cytochrom_B_N PF00033.14 ETO25051.1 - 0.032 13.5 0.0 0.041 13.2 0.0 1.1 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Peptidase_S49_N PF08496.5 ETO25051.1 - 0.085 12.6 3.1 0.14 11.9 2.1 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal YlqD PF11068.3 ETO25051.1 - 2 8.4 13.0 1.6 8.8 7.8 1.6 2 0 0 2 2 2 0 YlqD protein DUF2977 PF11192.3 ETO25052.1 - 0.049 13.4 1.7 0.085 12.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2977) DUF4094 PF13334.1 ETO25052.1 - 1.4 9.3 5.7 4.3 7.8 0.0 2.7 2 2 0 2 2 2 0 Domain of unknown function (DUF4094) ATP-synt_8 PF00895.15 ETO25052.1 - 2.4 8.4 6.3 11 6.2 0.1 2.8 3 0 0 3 3 3 0 ATP synthase protein 8 MSA-2c PF12238.3 ETO25053.1 - 0.14 11.8 0.5 0.2 11.2 0.3 1.3 1 1 0 1 1 1 0 Merozoite surface antigen 2c DCP2 PF05026.8 ETO25055.1 - 0.0079 16.0 3.3 0.1 12.4 0.8 2.6 2 1 0 2 2 2 1 Dcp2, box A domain TrwB_AAD_bind PF10412.4 ETO25055.1 - 0.14 10.7 0.1 0.18 10.3 0.1 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF106 PF01956.11 ETO25056.1 - 0.045 13.2 4.8 0.069 12.6 0.0 3.5 3 1 0 3 3 3 0 Integral membrane protein DUF106 DUF3439 PF11921.3 ETO25056.1 - 9.6 5.9 13.9 3.5 7.4 7.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) KIAA1430 PF13879.1 ETO25057.1 - 1.2e-08 35.2 15.1 1.2e-08 35.2 10.5 3.0 2 1 0 2 2 2 1 KIAA1430 homologue PspB PF06667.7 ETO25057.1 - 0.052 13.4 5.2 0.34 10.8 0.1 2.7 1 1 1 2 2 2 0 Phage shock protein B Zein PF01559.11 ETO25057.1 - 0.15 11.2 2.7 0.24 10.6 1.9 1.2 1 0 0 1 1 1 0 Zein seed storage protein PTR2 PF00854.16 ETO25058.1 - 2.4e-47 161.4 16.7 8e-41 140.0 9.4 2.7 2 1 0 2 2 2 2 POT family Glyco_hydro_47 PF01532.15 ETO25059.1 - 1.8e-28 99.3 0.1 2.2e-28 99.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Ycf1 PF05758.7 ETO25061.1 - 0.049 11.3 0.9 0.063 10.9 0.6 1.2 1 0 0 1 1 1 0 Ycf1 DUF1032 PF06278.6 ETO25061.1 - 0.46 8.9 12.0 0.35 9.2 7.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1032) DUF2718 PF10918.3 ETO25062.1 - 0.48 10.4 9.9 1.8 8.6 5.8 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2718) AF-4 PF05110.8 ETO25063.1 - 4.1 5.1 29.8 4.9 4.8 20.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF4604 PF15377.1 ETO25063.1 - 4.6 7.4 35.2 0.69 10.1 15.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4604) BTB_2 PF02214.17 ETO25064.1 - 7.7e-20 70.9 0.1 1.4e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 ETO25064.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain DUF2146 PF10220.4 ETO25065.1 - 0.0011 17.1 1.3 0.0011 17.1 0.9 1.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2146) MMR_HSR1 PF01926.18 ETO25065.1 - 0.031 14.2 0.1 0.062 13.2 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF3807 PF12720.2 ETO25066.1 - 3.1 7.9 19.3 0.49 10.5 10.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Ndc1_Nup PF09531.5 ETO25066.1 - 6.7 5.0 8.5 8.5 4.6 5.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PRP38_assoc PF12871.2 ETO25067.1 - 7.9e-05 23.1 27.6 7.9e-05 23.1 19.2 2.9 2 1 0 2 2 2 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF1777 PF08648.7 ETO25067.1 - 0.0016 18.1 23.3 0.0016 18.1 16.1 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1777) DUF751 PF05421.6 ETO25067.1 - 0.044 14.0 1.9 0.05 13.8 0.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF751) eIF3_N PF09440.5 ETO25070.1 - 6.9e-13 48.9 15.8 2.4e-05 24.5 0.1 3.2 2 1 0 2 2 2 2 eIF3 subunit 6 N terminal domain DC_STAMP PF07782.8 ETO25070.1 - 0.028 14.0 0.0 0.075 12.6 0.0 1.6 1 1 0 1 1 1 0 DC-STAMP-like protein Myc_N PF01056.13 ETO25070.1 - 0.028 13.5 0.2 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region PCI PF01399.22 ETO25071.1 - 6.4e-10 39.2 0.6 1.1e-09 38.5 0.4 1.4 1 0 0 1 1 1 1 PCI domain DUF3288 PF11691.3 ETO25071.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3288) SBF2 PF12335.3 ETO25072.1 - 0.012 14.9 2.9 0.012 14.9 2.0 1.8 1 1 1 2 2 2 0 Myotubularin protein HsdM_N PF12161.3 ETO25073.1 - 6.3 7.2 14.5 12 6.3 0.2 3.1 3 0 0 3 3 3 0 HsdM N-terminal domain NOA36 PF06524.7 ETO25073.1 - 7.7 5.6 10.2 14 4.8 7.1 1.4 1 0 0 1 1 1 0 NOA36 protein Aldo_ket_red PF00248.16 ETO25074.1 - 1.6e-32 112.4 0.0 2.6e-32 111.7 0.0 1.2 1 1 1 2 2 2 1 Aldo/keto reductase family Bacillus_HBL PF05791.6 ETO25074.1 - 0.053 12.8 0.5 0.09 12.1 0.1 1.5 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) WD40 PF00400.27 ETO25076.1 - 1.8e-10 40.3 5.1 2.4e-09 36.7 0.3 2.5 2 1 0 2 2 2 2 WD domain, G-beta repeat ShK PF01549.19 ETO25077.1 - 1.1e-13 51.2 27.2 8.6e-09 35.6 7.5 3.3 4 0 0 4 4 4 2 ShK domain-like 2OG-FeII_Oxy_3 PF13640.1 ETO25077.1 - 4e-06 27.2 0.1 2.4e-05 24.7 0.1 2.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Mucin PF01456.12 ETO25077.1 - 0.0061 16.3 3.2 0.0089 15.8 2.2 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein Pox_P21 PF05313.7 ETO25077.1 - 0.21 10.8 2.2 0.99 8.6 0.1 2.5 3 0 0 3 3 3 0 Poxvirus P21 membrane protein Ctr PF04145.10 ETO25079.1 - 0.0037 17.3 0.1 0.011 15.7 0.1 1.8 1 0 0 1 1 1 1 Ctr copper transporter family F-box-like PF12937.2 ETO25079.1 - 0.11 12.1 3.0 0.082 12.6 0.4 2.1 2 0 0 2 2 2 0 F-box-like FERM_C PF09380.5 ETO25080.1 - 0.1 12.8 1.0 0.2 11.9 0.2 1.9 2 0 0 2 2 2 0 FERM C-terminal PH-like domain Sulfatase PF00884.18 ETO25081.1 - 1.3e-22 80.4 0.0 1.8e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 ETO25081.1 - 2.1e-07 31.2 0.0 3e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 ETO25081.1 - 0.039 13.2 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Kelch_6 PF13964.1 ETO25083.1 - 0.00011 22.2 0.5 0.35 11.1 0.1 4.2 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 ETO25083.1 - 0.0002 21.0 0.4 0.0073 16.0 0.1 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.20 ETO25083.1 - 0.0023 17.4 3.6 0.028 13.9 0.4 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETO25083.1 - 0.022 14.5 1.5 0.76 9.5 0.1 3.1 2 1 1 3 3 3 0 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO25083.1 - 0.065 13.4 0.2 0.46 10.7 0.0 2.4 1 1 1 2 2 2 0 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO25083.1 - 0.067 13.1 0.0 7 6.7 0.1 3.6 4 0 0 4 4 4 0 Kelch motif WD40 PF00400.27 ETO25084.1 - 5.6e-74 241.5 18.6 7.6e-13 47.8 0.1 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat Kelch_1 PF01344.20 ETO25084.1 - 1.6e-06 27.5 14.2 0.00017 21.0 0.9 4.2 5 0 0 5 5 5 2 Kelch motif Nup160 PF11715.3 ETO25084.1 - 2.4e-06 25.9 8.1 0.033 12.3 0.1 4.4 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Kelch_2 PF07646.10 ETO25084.1 - 8e-06 25.4 5.3 0.0062 16.2 0.3 4.8 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 ETO25084.1 - 0.00061 19.6 6.0 0.062 13.2 0.9 4.2 5 0 0 5 5 5 1 Kelch motif Kelch_6 PF13964.1 ETO25084.1 - 0.0011 19.1 13.4 0.36 11.0 0.6 5.8 7 0 0 7 7 6 1 Kelch motif Kelch_3 PF13415.1 ETO25084.1 - 0.0029 17.7 0.2 0.44 10.7 0.0 3.6 3 0 0 3 3 3 1 Galactose oxidase, central domain Cytochrom_D1 PF02239.11 ETO25084.1 - 0.0051 15.1 0.2 0.057 11.7 0.1 2.4 1 1 2 3 3 3 2 Cytochrome D1 heme domain PD40 PF07676.7 ETO25084.1 - 0.0099 15.5 6.6 4 7.2 0.1 4.8 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO25084.1 - 0.022 14.2 0.0 0.13 11.6 0.0 2.0 1 1 0 1 1 1 0 PQQ-like domain Kelch_4 PF13418.1 ETO25084.1 - 0.034 13.9 1.4 5.3 6.8 0.1 3.6 3 0 0 3 3 3 0 Galactose oxidase, central domain WD40 PF00400.27 ETO25085.1 - 1.8e-72 236.8 28.1 4.7e-12 45.2 0.0 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO25085.1 - 4.5e-09 36.2 0.1 0.027 14.1 0.0 3.8 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO25085.1 - 3.2e-08 32.1 11.4 0.53 8.3 0.1 6.0 1 1 4 5 5 5 5 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO25085.1 - 1.9e-05 23.1 1.3 0.74 8.0 0.0 4.0 1 1 2 4 4 4 2 Cytochrome D1 heme domain Str_synth PF03088.11 ETO25085.1 - 7.7e-05 22.6 0.2 9.8 6.2 0.0 5.4 6 1 1 7 7 6 0 Strictosidine synthase MMS1_N PF10433.4 ETO25085.1 - 0.00047 18.4 0.2 0.42 8.7 0.0 3.6 2 1 1 4 4 4 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF1652 PF07865.6 ETO25085.1 - 0.0035 16.9 0.1 11 5.6 0.0 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF1652) Nucleoporin_N PF08801.6 ETO25085.1 - 0.0058 15.4 6.5 1.5 7.5 0.7 4.5 1 1 1 2 2 2 1 Nup133 N terminal like AcetylCoA_hyd_C PF13336.1 ETO25085.1 - 0.014 15.1 0.2 0.63 9.6 0.0 3.0 2 1 1 3 3 3 0 Acetyl-CoA hydrolase/transferase C-terminal domain SoxZ PF08770.6 ETO25085.1 - 0.015 14.6 0.1 19 4.7 0.0 4.4 5 0 0 5 5 5 0 Sulphur oxidation protein SoxZ PLD_C PF12357.3 ETO25085.1 - 0.031 13.7 0.0 20 4.8 0.0 3.9 4 0 0 4 4 4 0 Phospholipase D C terminal PD40 PF07676.7 ETO25085.1 - 0.054 13.1 7.5 25 4.6 0.0 5.5 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO25085.1 - 0.079 13.2 5.7 12 6.2 0.0 4.8 4 2 2 6 6 6 0 Resistin DUF1258 PF06869.7 ETO25085.1 - 0.13 11.3 1.2 1.1 8.2 0.0 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF1258) Proteasome_A_N PF10584.4 ETO25085.1 - 0.2 11.0 9.1 8 5.8 0.0 4.7 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature IL12p40_C PF10420.4 ETO25085.1 - 0.43 10.7 7.4 18 5.5 0.1 4.1 2 2 0 2 2 2 0 Cytokine interleukin-12p40 C-terminus Alk_phosphatase PF00245.15 ETO25087.1 - 2.9e-39 134.9 0.0 3.5e-37 128.0 0.0 2.3 2 1 0 2 2 2 2 Alkaline phosphatase PAS_11 PF14598.1 ETO25087.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 PAS domain Kelch_1 PF01344.20 ETO25088.1 - 0.069 12.7 7.8 0.045 13.3 2.9 2.6 3 0 0 3 3 3 0 Kelch motif DUF4312 PF14189.1 ETO25090.1 - 0.05 13.4 1.4 0.082 12.7 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4312) DUF848 PF05852.6 ETO25090.1 - 0.12 12.2 0.4 0.18 11.6 0.3 1.2 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Prp19 PF08606.6 ETO25091.1 - 1.7e-31 107.7 1.3 2.6e-31 107.1 0.9 1.3 1 0 0 1 1 1 1 Prp19/Pso4-like zf-Nse PF11789.3 ETO25091.1 - 1.5e-07 30.8 0.7 2.8e-07 29.9 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 ETO25091.1 - 8.5e-05 22.4 0.0 0.00022 21.1 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-RING_UBOX PF13445.1 ETO25091.1 - 0.0074 15.9 0.4 0.03 14.0 0.2 2.1 1 1 1 2 2 2 1 RING-type zinc-finger DUF3552 PF12072.3 ETO25091.1 - 0.016 14.4 2.9 0.023 13.9 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Rtf2 PF04641.7 ETO25091.1 - 0.044 12.9 0.7 0.19 10.8 0.0 2.2 2 1 0 2 2 2 0 Rtf2 RING-finger Cep57_CLD_2 PF14197.1 ETO25091.1 - 0.25 11.2 3.5 0.17 11.8 0.7 1.9 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 G-alpha PF00503.15 ETO25092.1 - 2.3e-17 62.7 0.9 4.2e-17 61.9 0.6 1.4 1 1 0 1 1 1 1 G-protein alpha subunit Arch_ATPase PF01637.13 ETO25092.1 - 0.00011 21.9 0.3 0.00014 21.6 0.2 1.2 1 0 0 1 1 1 1 Archaeal ATPase DUF815 PF05673.8 ETO25092.1 - 0.00036 19.5 0.0 0.0005 19.0 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.1 ETO25092.1 - 0.00059 19.4 0.0 0.00082 19.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 ETO25092.1 - 0.00073 19.8 0.0 0.0009 19.5 0.0 1.4 1 1 0 1 1 1 1 ABC transporter SRPRB PF09439.5 ETO25092.1 - 0.00078 18.6 3.3 0.13 11.4 0.1 2.3 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit RNA_helicase PF00910.17 ETO25092.1 - 0.0029 17.7 0.0 0.0046 17.1 0.0 1.4 1 0 0 1 1 1 1 RNA helicase Rad17 PF03215.10 ETO25092.1 - 0.004 15.9 0.1 0.0053 15.4 0.0 1.2 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 ETO25092.1 - 0.0041 17.3 0.0 0.0067 16.6 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 ETO25092.1 - 0.0051 16.0 0.0 0.006 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 ETO25092.1 - 0.0068 16.4 0.0 0.0074 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 ETO25092.1 - 0.013 14.3 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_23 PF13476.1 ETO25092.1 - 0.017 15.4 0.9 0.017 15.4 0.6 1.4 1 1 0 1 1 1 0 AAA domain PRK PF00485.13 ETO25092.1 - 0.021 14.3 0.1 0.14 11.6 0.0 2.0 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.1 ETO25092.1 - 0.022 14.2 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.1 ETO25092.1 - 0.023 14.6 0.1 0.032 14.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 ETO25092.1 - 0.031 13.7 0.1 0.07 12.6 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 ETO25092.1 - 0.036 13.9 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 ETO25092.1 - 0.041 13.0 0.0 0.12 11.4 0.0 1.7 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI DAP3 PF10236.4 ETO25092.1 - 0.045 12.6 0.1 0.15 11.0 0.0 1.8 1 1 1 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_5 PF07728.9 ETO25092.1 - 0.048 13.3 0.1 0.085 12.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETO25092.1 - 0.049 13.7 0.0 0.09 12.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 ETO25092.1 - 0.058 13.3 0.1 0.1 12.5 0.1 1.5 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.9 ETO25092.1 - 0.068 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase MMR_HSR1 PF01926.18 ETO25092.1 - 0.12 12.3 0.7 0.58 10.1 0.5 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase Sigma54_activ_2 PF14532.1 ETO25092.1 - 0.14 12.1 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain Bromodomain PF00439.20 ETO25093.1 - 0.0099 15.7 0.1 0.018 14.9 0.1 1.5 1 0 0 1 1 1 1 Bromodomain DUF2251 PF10008.4 ETO25093.1 - 0.1 12.7 0.1 0.2 11.7 0.0 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2251) DUF2762 PF10960.3 ETO25093.1 - 0.19 11.4 0.8 0.24 11.1 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2762) V_ATPase_I PF01496.14 ETO25094.1 - 0.0047 14.8 2.3 0.0058 14.5 1.6 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF3972 PF13118.1 ETO25094.1 - 0.017 15.1 7.7 0.017 15.1 5.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3972) GreA_GreB_N PF03449.10 ETO25094.1 - 0.037 14.0 1.2 0.22 11.5 0.1 2.3 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal Cas_Cmr5 PF09701.5 ETO25094.1 - 0.046 13.9 3.6 0.34 11.0 0.0 2.6 1 1 2 3 3 3 0 CRISPR-associated protein (Cas_Cmr5) NAGLU_N PF12971.2 ETO25095.1 - 2.3e-05 23.9 0.2 0.00017 21.1 0.0 2.1 1 1 1 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Peptidase_M56 PF05569.6 ETO25095.1 - 0.01 14.8 0.2 0.014 14.3 0.1 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 Ion_trans PF00520.26 ETO25095.1 - 0.05 12.8 1.1 0.17 11.0 0.1 1.9 2 0 0 2 2 2 0 Ion transport protein FixQ PF05545.6 ETO25095.1 - 4.7 6.9 5.4 57 3.4 3.7 2.4 1 1 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ NAGLU PF05089.7 ETO25096.1 - 9.3e-75 251.4 2.9 2.1e-73 246.9 2.0 2.4 1 1 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.2 ETO25096.1 - 4e-33 114.9 9.5 1.1e-32 113.5 6.6 1.7 1 1 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU PF05089.7 ETO25097.1 - 1.2e-39 136.0 2.2 1.2e-39 136.0 1.5 2.5 2 1 0 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.2 ETO25097.1 - 2.6e-33 115.5 9.6 7.5e-33 114.0 6.7 1.7 1 1 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain RhoGEF PF00621.15 ETO25098.1 - 0.00011 22.1 0.6 0.0002 21.2 0.4 1.5 1 0 0 1 1 1 1 RhoGEF domain Lipase_GDSL PF00657.17 ETO25098.1 - 0.042 13.6 0.1 0.062 13.1 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase PT PF04886.7 ETO25099.1 - 4.9e-122 396.9 859.0 1.8e-05 23.9 18.7 40.6 5 2 19 24 24 24 12 PT repeat SPRY PF00622.23 ETO25100.1 - 4e-12 46.3 1.9 1.4e-10 41.3 0.5 2.5 2 1 1 3 3 3 2 SPRY domain Glyco_hydro_53 PF07745.8 ETO25101.1 - 2.8e-15 55.9 0.1 3.7e-13 48.9 0.0 2.5 1 1 2 3 3 3 2 Glycosyl hydrolase family 53 DUF775 PF05603.7 ETO25101.1 - 0.023 14.2 0.3 0.031 13.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Thiolase_N PF00108.18 ETO25103.1 - 1.1e-55 188.4 1.3 1.3e-53 181.6 0.2 2.8 2 1 0 2 2 2 2 Thiolase, N-terminal domain Thiolase_C PF02803.13 ETO25103.1 - 1.3e-26 92.3 0.0 2.9e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 ETO25103.1 - 0.038 14.0 0.0 0.31 11.0 0.0 2.5 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF2256 PF10013.4 ETO25103.1 - 0.09 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) Adaptin_N PF01602.15 ETO25104.1 - 8.9e-16 57.2 0.1 1.1e-15 56.9 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Paramyxo_C PF01692.13 ETO25104.1 - 0.04 13.5 0.0 0.048 13.2 0.0 1.1 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c Thi4 PF01946.12 ETO25104.1 - 0.042 12.9 0.0 0.048 12.7 0.0 1.1 1 0 0 1 1 1 0 Thi4 family DUF310 PF03750.8 ETO25104.1 - 0.044 13.9 0.1 0.058 13.5 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF310) Daxx PF03344.10 ETO25106.1 - 1.4e-05 23.7 35.2 0.00011 20.8 11.1 2.3 2 0 0 2 2 2 2 Daxx Family Sigma70_ner PF04546.8 ETO25106.1 - 0.0043 16.7 29.8 0.091 12.3 4.8 2.5 2 0 0 2 2 2 2 Sigma-70, non-essential region Prothymosin PF03247.9 ETO25106.1 - 0.0088 16.1 44.1 0.027 14.6 13.1 3.2 3 0 0 3 3 3 2 Prothymosin/parathymosin family Nop14 PF04147.7 ETO25106.1 - 0.15 9.9 35.8 0.46 8.3 7.9 2.3 2 0 0 2 2 2 0 Nop14-like family ANAPC15 PF15243.1 ETO25106.1 - 0.5 10.4 38.3 0.036 14.1 7.6 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 BSP_II PF05432.6 ETO25106.1 - 1 8.5 31.2 3.4 6.8 9.4 2.7 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) ERM PF00769.14 ETO25106.1 - 1.3 8.5 29.8 3.1 7.2 11.1 2.4 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Nucleoplasmin PF03066.10 ETO25106.1 - 1.3 8.5 38.5 0.1 12.1 6.1 2.5 2 0 0 2 2 2 0 Nucleoplasmin Merozoite_SPAM PF07133.6 ETO25106.1 - 3 7.7 52.6 4.6 7.1 16.2 3.3 3 0 0 3 3 3 0 Merozoite surface protein (SPAM) FAM176 PF14851.1 ETO25106.1 - 3.7 7.2 22.0 5.3 6.7 3.5 2.9 2 0 0 2 2 2 0 FAM176 family Nop25 PF09805.4 ETO25106.1 - 6.9 6.7 36.7 2.3 8.2 4.5 2.8 3 0 0 3 3 3 0 Nucleolar protein 12 (25kDa) KIP1 PF07765.7 ETO25107.1 - 0.033 14.0 0.1 0.093 12.5 0.1 1.8 1 0 0 1 1 1 0 KIP1-like protein DUF3391 PF11871.3 ETO25107.1 - 1.4 9.1 6.4 0.14 12.4 0.5 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) BCD PF15461.1 ETO25108.1 - 0.018 14.5 0.3 0.022 14.1 0.2 1.1 1 0 0 1 1 1 0 Beta-carotene 15,15'-dioxygenase Polysacc_synt PF01943.12 ETO25108.1 - 0.037 13.3 1.4 0.055 12.7 1.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Glyco_transf_9 PF01075.12 ETO25108.1 - 0.066 12.4 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) DUF4293 PF14126.1 ETO25108.1 - 0.36 10.7 4.6 1.1 9.2 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) Pkinase PF00069.20 ETO25109.1 - 1.5e-05 24.2 0.1 1.5e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Imm46 PF15585.1 ETO25109.1 - 0.014 15.4 0.3 0.02 14.9 0.2 1.3 1 0 0 1 1 1 0 Immunity protein 46 Pkinase_Tyr PF07714.12 ETO25109.1 - 0.097 11.7 0.9 0.12 11.3 0.0 1.6 2 0 0 2 2 2 0 Protein tyrosine kinase Colicin-DNase PF12639.2 ETO25109.1 - 0.14 12.4 1.9 0.2 11.9 1.3 1.3 1 0 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin APC_CDC26 PF10471.4 ETO25109.1 - 0.85 10.3 7.6 2 9.1 5.1 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 WBS_methylT PF12589.3 ETO25109.1 - 5.3 7.6 11.7 1.1 9.8 4.8 2.3 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome Arm PF00514.18 ETO25110.1 - 0.0016 18.2 4.5 0.65 9.9 0.1 3.7 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 ETO25110.1 - 0.03 14.7 0.0 0.066 13.7 0.0 1.6 1 0 0 1 1 1 0 HEAT-like repeat HEAT_2 PF13646.1 ETO25110.1 - 0.072 13.3 0.1 0.23 11.7 0.1 1.8 2 0 0 2 2 2 0 HEAT repeats P12 PF12669.2 ETO25110.1 - 4.9 7.4 8.2 5.7 7.2 1.4 2.5 2 0 0 2 2 2 0 Virus attachment protein p12 family Bac_rhamnosid_N PF08531.5 ETO25111.1 - 0.00095 18.7 0.0 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Vac14_Fab1_bd PF12755.2 ETO25112.1 - 0.00029 21.1 1.2 0.13 12.6 0.2 2.8 1 1 1 2 2 2 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 ETO25112.1 - 0.0005 18.5 0.0 0.001 17.4 0.0 1.5 1 0 0 1 1 1 1 Adaptin N terminal region Cnd3 PF12719.2 ETO25112.1 - 0.00057 18.9 0.3 0.0076 15.2 0.1 2.5 1 1 1 2 2 2 2 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 ETO25112.1 - 0.0013 18.9 0.0 0.042 14.1 0.0 2.4 1 1 0 1 1 1 1 HEAT repeats YniB PF14002.1 ETO25112.1 - 0.0017 17.8 0.0 0.0038 16.6 0.0 1.5 1 0 0 1 1 1 1 YniB-like protein HEAT PF02985.17 ETO25112.1 - 0.002 18.0 0.0 0.095 12.8 0.0 3.2 3 0 0 3 3 3 1 HEAT repeat GRAB PF10375.4 ETO25113.1 - 0.037 13.7 0.1 0.081 12.6 0.1 1.6 1 0 0 1 1 1 0 GRIP-related Arf-binding domain Neur_chan_memb PF02932.11 ETO25115.1 - 0.064 13.1 1.9 0.083 12.7 1.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CD36 PF01130.16 ETO25116.1 - 1.2e-24 86.4 4.2 1.4e-24 86.2 2.9 1.1 1 0 0 1 1 1 1 CD36 family CD36 PF01130.16 ETO25117.1 - 1.7e-18 66.1 0.4 3.2e-18 65.2 0.3 1.4 1 1 0 1 1 1 1 CD36 family DUF3341 PF11821.3 ETO25117.1 - 0.017 14.5 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) HSP90 PF00183.13 ETO25118.1 - 4.6e-76 256.3 4.8 1.2e-73 248.3 1.9 2.4 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.1 ETO25118.1 - 0.0017 17.9 0.0 0.0043 16.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase hGDE_N PF14699.1 ETO25118.1 - 0.0031 17.3 0.1 0.22 11.4 0.0 2.7 2 0 0 2 2 2 1 N-terminal domain from the human glycogen debranching enzyme ABC2_membrane_3 PF12698.2 ETO25119.1 - 0.007 15.4 0.1 0.007 15.4 0.1 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein CAP_GLY PF01302.20 ETO25120.1 - 2.7e-08 33.3 0.2 5.4e-08 32.4 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain Peptidase_M43 PF05572.8 ETO25121.1 - 7.4e-07 28.8 2.1 1.4e-05 24.7 0.2 2.6 3 0 0 3 3 3 2 Pregnancy-associated plasma protein-A Radial_spoke_3 PF06098.6 ETO25123.1 - 1.3e-60 204.8 4.5 2.2e-60 204.1 3.1 1.3 1 0 0 1 1 1 1 Radial spoke protein 3 HisK_N PF09385.5 ETO25123.1 - 0.024 14.2 1.2 0.057 13.0 0.8 1.6 1 0 0 1 1 1 0 Histidine kinase N terminal YlqD PF11068.3 ETO25123.1 - 4.5 7.3 10.1 1.3 9.1 4.4 2.0 2 0 0 2 2 2 0 YlqD protein SAM_2 PF07647.12 ETO25125.1 - 0.014 15.2 0.1 0.066 13.0 0.1 2.1 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) KH_1 PF00013.24 ETO25128.1 - 0.009 15.6 0.1 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 ETO25128.1 - 0.021 14.4 0.2 0.036 13.7 0.1 1.4 1 0 0 1 1 1 0 KH domain KH_3 PF13014.1 ETO25129.1 - 2.5e-05 23.8 0.5 0.00019 20.9 0.5 2.4 2 0 0 2 2 2 1 KH domain KH_1 PF00013.24 ETO25129.1 - 0.00016 21.2 0.1 0.00049 19.6 0.1 1.8 1 0 0 1 1 1 1 KH domain Nup35_RRM_2 PF14605.1 ETO25129.1 - 0.0018 17.9 0.1 0.024 14.3 0.0 2.9 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.17 ETO25129.1 - 0.0034 16.9 0.0 0.67 9.6 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_5 PF13184.1 ETO25129.1 - 0.085 12.6 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 NusA-like KH domain Hat1_N PF10394.4 ETO25130.1 - 8.6e-23 81.1 3.0 8.6e-23 81.1 2.1 3.3 3 1 0 3 3 3 1 Histone acetyl transferase HAT1 N-terminus MOZ_SAS PF01853.13 ETO25130.1 - 0.00061 19.0 1.3 0.0013 18.0 0.9 1.5 1 0 0 1 1 1 1 MOZ/SAS family PGC7_Stella PF15549.1 ETO25130.1 - 0.11 12.5 4.2 0.14 12.1 2.3 1.6 1 1 0 1 1 1 0 PGC7/Stella/Dppa3 domain Acetyltransf_1 PF00583.19 ETO25130.1 - 0.14 12.2 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Kringle PF00051.13 ETO25130.1 - 0.2 11.7 4.4 0.5 10.5 3.1 1.6 1 0 0 1 1 1 0 Kringle domain Vps51 PF08700.6 ETO25131.1 - 2.4e-07 30.4 0.8 2.4e-07 30.4 0.5 2.4 1 1 2 3 3 3 1 Vps51/Vps67 Sec5 PF15469.1 ETO25131.1 - 0.023 14.4 7.6 0.031 14.0 5.3 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec5 COG2 PF06148.6 ETO25131.1 - 0.027 14.3 5.2 0.061 13.1 3.6 1.7 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 MAR_sialic_bdg PF10564.4 ETO25131.1 - 0.059 13.1 0.1 0.099 12.4 0.1 1.5 1 0 0 1 1 1 0 Sialic-acid binding micronemal adhesive repeat Herpes_UL45 PF05473.7 ETO25131.1 - 0.059 12.7 0.1 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 UL45 protein Phage_Nu1 PF07471.7 ETO25131.1 - 0.073 12.5 0.6 0.12 11.8 0.4 1.5 1 1 0 1 1 1 0 Phage DNA packaging protein Nu1 DUF16 PF01519.11 ETO25131.1 - 0.15 12.2 4.1 0.32 11.2 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF16 Adaptin_N PF01602.15 ETO25133.1 - 5.3e-62 209.8 9.6 6.3e-62 209.5 6.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 ETO25133.1 - 2.8e-13 50.2 3.6 8.1e-13 48.6 2.5 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain Peptidase_M9_N PF08453.5 ETO25133.1 - 0.077 12.3 3.7 4.4 6.6 0.3 2.9 3 0 0 3 3 3 0 Peptidase family M9 N-terminal UTP15_C PF09384.5 ETO25133.1 - 0.096 12.3 1.9 1.6 8.4 0.2 2.6 2 1 0 2 2 2 0 UTP15 C terminal FANCI_S2 PF14676.1 ETO25133.1 - 0.29 11.0 2.4 8.5 6.2 0.0 2.9 2 1 0 3 3 3 0 FANCI solenoid 2 RP-C_C PF11800.3 ETO25133.1 - 0.57 9.8 5.1 1.6 8.3 3.5 1.7 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF1840 PF08895.6 ETO25133.1 - 3.4 7.7 8.2 0.93 9.5 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) Gal_mutarotas_2 PF13802.1 ETO25134.1 - 1.2e-06 28.2 0.0 2.1e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Galactose mutarotase-like Glyco_hydro_31 PF01055.21 ETO25135.1 - 1.3e-141 472.4 7.4 1.6e-141 472.1 5.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Cytotoxic PF09000.5 ETO25135.1 - 0.084 12.9 0.1 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 Cytotoxic Kelch_1 PF01344.20 ETO25136.1 - 7.3e-07 28.6 5.2 5.5e-06 25.8 0.3 2.9 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 ETO25136.1 - 0.00012 22.1 0.0 0.01 15.9 0.0 2.9 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO25136.1 - 0.0016 18.5 13.7 0.0029 17.7 0.1 4.5 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.10 ETO25136.1 - 0.0033 17.1 1.2 0.093 12.5 0.1 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETO25136.1 - 0.007 16.1 1.4 0.078 12.7 0.0 3.3 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO25136.1 - 0.034 14.1 1.3 0.21 11.5 0.3 2.7 3 0 0 3 3 3 0 Kelch motif zf-TRAF PF02176.13 ETO25137.1 - 7.2e-08 32.6 8.8 7.2e-08 32.6 6.1 2.6 2 0 0 2 2 2 1 TRAF-type zinc finger IncA PF04156.9 ETO25137.1 - 0.0097 15.5 1.2 0.019 14.5 0.9 1.4 1 0 0 1 1 1 1 IncA protein bZIP_1 PF00170.16 ETO25137.1 - 0.048 13.6 3.7 0.69 9.9 0.2 2.6 2 0 0 2 2 2 0 bZIP transcription factor CPDase PF07823.6 ETO25137.1 - 0.059 12.8 1.5 0.13 11.7 1.0 1.5 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein CorA PF01544.13 ETO25137.1 - 0.076 12.0 0.3 0.11 11.4 0.2 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4047 PF13256.1 ETO25137.1 - 0.58 10.1 6.4 1.4 8.9 4.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) DUF2570 PF10828.3 ETO25137.1 - 0.61 9.7 3.5 0.32 10.6 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) PMSR PF01625.16 ETO25138.1 - 6.8e-15 55.2 0.3 6.8e-15 55.2 0.2 2.3 2 0 0 2 2 2 1 Peptide methionine sulfoxide reductase NUDIX PF00293.23 ETO25139.1 - 2.4e-09 36.9 0.1 3.3e-09 36.4 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain DUF2407 PF10302.4 ETO25139.1 - 0.14 12.3 0.3 0.18 11.9 0.1 1.5 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain G-alpha PF00503.15 ETO25140.1 - 2.5e-09 36.3 1.6 2.5e-09 36.3 1.1 1.9 2 0 0 2 2 2 2 G-protein alpha subunit DUF4234 PF14018.1 ETO25141.1 - 0.029 14.0 0.1 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) FAM60A PF15396.1 ETO25141.1 - 0.57 9.8 12.3 0.71 9.5 8.6 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Utp14 PF04615.8 ETO25141.1 - 3 5.8 34.6 3.7 5.6 24.0 1.0 1 0 0 1 1 1 0 Utp14 protein Sensor PF13796.1 ETO25142.1 - 0.00056 19.5 4.5 0.0011 18.5 3.1 1.7 1 1 0 1 1 1 1 Putative sensor CAP_GLY PF01302.20 ETO25143.1 - 3.3e-30 103.5 5.4 3.9e-16 58.5 0.2 2.3 2 0 0 2 2 2 2 CAP-Gly domain Menin PF05053.8 ETO25143.1 - 0.22 9.6 13.5 0.31 9.1 9.3 1.1 1 0 0 1 1 1 0 Menin Slu7 PF11708.3 ETO25144.1 - 8.1e-31 107.6 0.1 8.1e-31 107.6 0.1 2.0 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor MFS_1 PF07690.11 ETO25145.1 - 0.21 10.2 13.6 0.062 12.0 6.3 1.6 1 1 0 1 1 1 0 Major Facilitator Superfamily zf-DHHC PF01529.15 ETO25145.1 - 5.3 6.3 6.5 1.7 7.9 0.1 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase Sulfotransfer_2 PF03567.9 ETO25146.1 - 2.2e-06 27.5 0.4 2.7e-06 27.2 0.3 1.1 1 0 0 1 1 1 1 Sulfotransferase family G-alpha PF00503.15 ETO25147.1 - 7.9e-17 61.0 1.4 1e-16 60.6 1.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit G-alpha PF00503.15 ETO25148.1 - 4.7e-46 157.2 4.3 5.8e-46 156.9 3.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO25148.1 - 6.6e-11 41.7 0.2 1.2e-10 40.9 0.1 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family RasGAP PF00616.14 ETO25151.1 - 9.9e-40 136.3 2.8 9.9e-40 136.3 2.0 2.1 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 ETO25151.1 - 9.8e-13 48.0 2.0 9.8e-13 48.0 1.4 2.6 3 1 1 4 4 4 1 RasGAP C-terminus DASH_Dad4 PF08650.5 ETO25151.1 - 0.047 13.6 0.0 5.5 6.9 0.1 3.3 2 0 0 2 2 2 0 DASH complex subunit Dad4 LOH1CR12 PF10158.4 ETO25151.1 - 0.051 13.3 1.4 3.5 7.4 0.0 3.0 2 0 0 2 2 2 0 Tumour suppressor protein Ank_2 PF12796.2 ETO25152.1 - 1.5e-27 95.7 1.3 9.7e-14 51.4 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETO25152.1 - 3.8e-21 73.7 0.0 2.5e-07 30.1 0.1 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 ETO25152.1 - 1.3e-19 70.1 1.1 2.2e-07 31.2 0.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO25152.1 - 7.3e-19 65.9 0.9 6.2e-05 22.8 0.0 5.0 5 1 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 ETO25152.1 - 3e-17 62.2 0.2 6.3e-08 32.6 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) DUF1450 PF07293.6 ETO25152.1 - 0.11 12.4 0.7 0.92 9.5 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1450) DUF342 PF03961.8 ETO25154.1 - 0.056 11.8 2.3 0.056 11.8 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) UCH PF00443.24 ETO25154.1 - 0.17 10.9 2.1 0.17 10.9 1.4 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase PsbI PF02532.9 ETO25154.1 - 1.4 8.6 3.8 1.9 8.1 1.6 2.0 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) HWE_HK PF07536.9 ETO25155.1 - 0.13 12.7 0.2 0.85 10.0 0.0 2.2 2 0 0 2 2 2 0 HWE histidine kinase Lactonase PF10282.4 ETO25156.1 - 0.17 10.9 0.0 3.9 6.4 0.0 2.0 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Pkinase PF00069.20 ETO25157.1 - 0.023 13.8 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Pox_RNA_Pol_19 PF05320.7 ETO25158.1 - 7.3 6.3 17.9 0.044 13.5 5.2 2.3 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Globin PF00042.17 ETO25159.1 - 9.1e-11 42.0 1.0 1.7e-08 34.7 0.1 3.0 2 1 0 2 2 2 2 Globin AAA PF00004.24 ETO25161.1 - 7e-41 139.5 0.0 1.7e-40 138.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETO25161.1 - 4.3e-06 26.8 0.0 0.00043 20.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 ETO25161.1 - 8e-06 25.6 0.1 4.9e-05 23.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 ETO25161.1 - 1e-05 25.5 0.0 1e-05 25.5 0.0 2.7 3 1 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 ETO25161.1 - 6.2e-05 23.0 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 ETO25161.1 - 0.00037 19.5 0.1 0.0012 17.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 ETO25161.1 - 0.0006 20.6 0.7 0.0019 18.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 ETO25161.1 - 0.00082 18.4 0.0 0.0016 17.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 ETO25161.1 - 0.0027 17.8 0.0 0.014 15.5 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_19 PF13245.1 ETO25161.1 - 0.0038 16.9 0.2 0.0076 15.9 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain Sigma54_activ_2 PF14532.1 ETO25161.1 - 0.0058 16.6 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.1 ETO25161.1 - 0.007 16.2 0.0 0.029 14.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 ETO25161.1 - 0.0071 15.4 0.0 0.015 14.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 ETO25161.1 - 0.0094 15.8 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 ETO25161.1 - 0.015 15.2 1.2 0.022 14.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 ETO25161.1 - 0.027 14.0 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 ETO25161.1 - 0.031 13.7 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 ETO25161.1 - 0.043 12.9 0.0 0.099 11.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 ETO25161.1 - 0.046 14.0 3.2 0.16 12.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.21 ETO25161.1 - 0.075 12.4 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 ETO25161.1 - 0.077 12.5 4.4 0.12 11.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain FAM176 PF14851.1 ETO25161.1 - 0.34 10.5 3.9 0.66 9.6 2.7 1.4 1 0 0 1 1 1 0 FAM176 family AAA_11 PF13086.1 ETO25161.1 - 1 8.9 0.0 1 8.9 0.0 2.8 2 1 0 2 2 1 0 AAA domain Arch_ATPase PF01637.13 ETO25161.1 - 4.1 7.0 7.9 1.9 8.0 0.0 3.3 3 1 0 3 3 2 0 Archaeal ATPase DUF1910 PF08928.5 ETO25161.1 - 7.5 6.6 7.5 0.48 10.4 0.7 2.2 3 0 0 3 3 2 0 Domain of unknown function (DUF1910) Pyr_redox_2 PF07992.9 ETO25162.1 - 8.5e-15 55.1 0.3 1.4e-14 54.4 0.2 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETO25162.1 - 1.3e-05 25.3 0.0 1.6e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETO25162.1 - 0.17 10.7 0.5 0.66 8.8 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETO25162.1 - 0.18 12.2 2.7 22 5.5 0.8 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HECT PF00632.20 ETO25163.1 - 1.2e-72 244.7 0.2 3.1e-72 243.4 0.1 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 ETO25163.1 - 4.5e-09 36.4 0.2 1.1e-08 35.1 0.1 1.8 1 0 0 1 1 1 1 SPRY domain Laminin_G_3 PF13385.1 ETO25164.1 - 4.1e-17 62.8 0.9 8.8e-17 61.7 0.6 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Pentaxin PF00354.12 ETO25164.1 - 0.047 13.1 0.0 0.24 10.8 0.0 1.9 1 1 0 1 1 1 0 Pentaxin family ERp29 PF07749.7 ETO25165.1 - 0.048 14.2 0.7 4.2 8.0 0.2 2.2 1 1 1 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain Circo_capsid PF02443.10 ETO25167.1 - 0.48 9.7 10.0 0.47 9.7 6.9 1.2 1 0 0 1 1 1 0 Circovirus capsid protein Nop25 PF09805.4 ETO25167.1 - 1.3 9.1 39.3 1.9 8.5 27.3 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF1777 PF08648.7 ETO25167.1 - 6.1 6.5 42.1 7.6 6.2 29.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) WD40 PF00400.27 ETO25168.1 - 0.00022 20.9 0.1 0.0075 16.1 0.0 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Synuclein PF01387.12 ETO25170.1 - 0.013 15.4 2.2 0.037 13.9 1.5 1.7 1 0 0 1 1 1 0 Synuclein HALZ PF02183.13 ETO25170.1 - 0.02 14.6 16.1 0.055 13.1 0.5 3.9 4 0 0 4 4 4 0 Homeobox associated leucine zipper APG6 PF04111.7 ETO25170.1 - 0.079 11.9 39.1 0.75 8.7 12.1 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 MS_channel PF00924.13 ETO25170.1 - 0.54 9.5 4.5 0.14 11.4 0.6 2.0 2 1 0 2 2 2 0 Mechanosensitive ion channel Mnd1 PF03962.10 ETO25170.1 - 1.5 8.4 30.2 3.8 7.1 5.5 2.7 2 1 0 2 2 2 0 Mnd1 family MMR_HSR1 PF01926.18 ETO25173.1 - 6.4e-06 26.1 0.3 2.7e-05 24.0 0.0 2.2 1 1 1 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 ETO25173.1 - 1.7e-05 24.0 2.3 2.2e-05 23.7 0.2 2.1 2 1 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 ETO25173.1 - 0.00023 21.5 0.2 0.00023 21.5 0.1 2.2 1 1 1 2 2 2 1 ABC transporter AAA_25 PF13481.1 ETO25173.1 - 0.0016 17.8 0.0 0.0035 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF2457 PF10446.4 ETO25173.1 - 0.0019 17.0 10.7 0.0019 17.0 7.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) AAA_29 PF13555.1 ETO25173.1 - 0.0038 16.7 0.1 0.0074 15.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 ETO25173.1 - 0.0051 15.7 0.0 0.0069 15.3 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Miro PF08477.8 ETO25173.1 - 0.0088 16.5 0.9 0.017 15.6 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein RNA_helicase PF00910.17 ETO25173.1 - 0.012 15.7 0.2 0.13 12.4 0.0 2.7 2 1 0 2 2 2 0 RNA helicase AAA_19 PF13245.1 ETO25173.1 - 0.015 15.0 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 ETO25173.1 - 0.02 15.0 0.1 0.058 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 ETO25173.1 - 0.025 13.7 1.3 0.036 13.2 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein DUF4611 PF15387.1 ETO25173.1 - 0.027 14.5 8.5 0.078 13.1 5.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) AAA_16 PF13191.1 ETO25173.1 - 0.028 14.3 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF2887 PF11103.3 ETO25173.1 - 0.032 13.8 0.8 0.032 13.8 0.6 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF2887) UPF0079 PF02367.12 ETO25173.1 - 0.066 12.8 0.1 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activ_2 PF14532.1 ETO25173.1 - 0.079 13.0 0.4 0.41 10.7 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.1 ETO25173.1 - 0.093 12.6 0.1 0.093 12.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain RXT2_N PF08595.6 ETO25173.1 - 0.11 12.2 9.7 0.52 10.1 6.7 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal FLO_LFY PF01698.11 ETO25173.1 - 0.36 9.6 11.8 0.22 10.3 6.3 1.8 2 0 0 2 2 2 0 Floricaula / Leafy protein DUF2076 PF09849.4 ETO25173.1 - 1.4 8.9 9.4 2.5 8.0 6.5 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) UPF0560 PF10577.4 ETO25173.1 - 1.4 7.0 10.8 2.1 6.5 7.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF1510 PF07423.6 ETO25173.1 - 1.6 8.0 18.8 3.9 6.7 10.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) FAM176 PF14851.1 ETO25173.1 - 5.2 6.7 7.7 13 5.4 5.4 1.7 1 0 0 1 1 1 0 FAM176 family FtsK_SpoIIIE PF01580.13 ETO25173.1 - 5.3 6.4 7.7 0.18 11.2 0.5 1.9 1 1 1 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 ETO25173.1 - 9.2 6.0 10.4 18 5.1 0.0 3.4 2 1 1 3 3 3 0 Dynamin family Barttin PF15462.1 ETO25174.1 - 5.2 6.6 7.3 2.4 7.7 2.0 2.1 2 0 0 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) LRR_4 PF12799.2 ETO25175.1 - 2e-07 30.4 8.0 0.00051 19.5 1.3 2.3 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.7 ETO25175.1 - 9.9e-06 25.4 1.4 2.2e-05 24.2 1.0 1.7 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_8 PF13855.1 ETO25175.1 - 3.8e-05 23.3 7.0 0.0006 19.5 0.9 2.4 2 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 ETO25175.1 - 0.0012 18.5 2.7 0.28 11.3 0.2 3.4 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_7 PF13504.1 ETO25175.1 - 0.0018 18.1 1.3 3.7 8.1 0.0 3.1 2 0 0 2 2 2 2 Leucine rich repeat TFIIS_M PF07500.9 ETO25175.1 - 0.14 12.2 0.2 3.3 7.8 0.1 2.1 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS), central domain LRR_6 PF13516.1 ETO25175.1 - 0.53 10.5 5.5 8 6.8 0.3 3.1 3 0 0 3 3 3 0 Leucine Rich repeat SSP160 PF06933.6 ETO25176.1 - 0.0049 14.9 4.4 0.0066 14.5 3.0 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 SAM_2 PF07647.12 ETO25177.1 - 0.00081 19.1 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO25177.1 - 0.0039 17.3 0.1 0.0095 16.0 0.1 1.7 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 ETO25177.1 - 0.0059 16.3 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Ste50p-SAM PF09235.5 ETO25177.1 - 0.022 14.7 0.0 0.057 13.4 0.0 1.7 1 0 0 1 1 1 0 Ste50p, sterile alpha motif ICL PF00463.16 ETO25178.1 - 3.5e-14 51.9 0.0 3.9e-14 51.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 ETO25178.1 - 1.7e-07 30.7 0.1 2.3e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Nuc_rec_co-act PF08815.5 ETO25178.1 - 0.0046 16.4 0.3 0.0084 15.6 0.2 1.4 1 0 0 1 1 1 1 Nuclear receptor coactivator DUF1249 PF06853.7 ETO25179.1 - 0.013 15.0 0.5 1.8 8.2 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1249) gp37_C PF12604.3 ETO25180.1 - 0.12 12.1 1.3 0.17 11.6 0.2 1.7 2 0 0 2 2 2 0 Tail fiber protein gp37 C terminal HYR PF02494.11 ETO25181.1 - 0.0011 18.8 0.1 0.0098 15.8 0.0 2.1 2 0 0 2 2 2 1 HYR domain Herpes_IE2_3 PF03361.9 ETO25181.1 - 0.029 13.7 0.1 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 Synaphin PF05835.7 ETO25181.1 - 0.31 11.2 10.8 0.56 10.3 7.5 1.5 1 0 0 1 1 1 0 Synaphin protein MIP-T3 PF10243.4 ETO25182.1 - 9e-06 24.4 34.2 1.1e-05 24.1 23.7 1.0 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF1510 PF07423.6 ETO25182.1 - 0.27 10.5 28.6 0.011 15.1 10.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF1777 PF08648.7 ETO25182.1 - 0.7 9.6 41.9 1.5 8.5 28.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) NAM-associated PF14303.1 ETO25182.1 - 2.1 8.6 30.5 0.36 11.1 18.4 1.8 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain TPR_12 PF13424.1 ETO25183.1 - 4.5e-47 157.8 15.8 5.4e-19 67.9 1.5 3.9 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO25183.1 - 5e-24 83.7 31.5 1.6e-12 46.8 1.2 4.4 1 1 4 5 5 5 5 TPR repeat TPR_1 PF00515.23 ETO25183.1 - 2.5e-18 64.8 24.6 8.3e-08 31.5 0.5 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO25183.1 - 1.6e-17 61.9 17.0 2.2e-06 27.1 0.2 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO25183.1 - 3.9e-17 60.6 1.4 1.1e-05 24.9 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO25183.1 - 6.7e-11 41.7 0.0 0.00018 21.2 0.0 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO25183.1 - 5.2e-10 38.3 27.1 8.8e-05 22.0 0.4 6.3 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO25183.1 - 3.8e-08 33.7 0.0 0.0058 17.2 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO25183.1 - 2.2e-06 27.4 2.6 0.063 13.5 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat Kelch_6 PF13964.1 ETO25183.1 - 1.8e-05 24.6 1.2 1.4 9.2 0.0 4.6 3 1 1 4 4 4 2 Kelch motif MIT PF04212.13 ETO25183.1 - 4.6e-05 23.2 3.3 0.099 12.5 0.0 4.1 4 0 0 4 4 3 1 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.4 ETO25183.1 - 6.6e-05 22.0 0.1 0.61 9.3 0.0 3.5 3 0 0 3 3 3 1 SHNi-TPR TPR_6 PF13174.1 ETO25183.1 - 0.00013 22.2 0.7 5.7 7.6 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat Kelch_5 PF13854.1 ETO25183.1 - 0.00076 19.3 0.1 13 5.8 0.1 4.2 4 0 0 4 4 4 0 Kelch motif TPR_19 PF14559.1 ETO25183.1 - 0.0011 19.2 0.1 0.0064 16.8 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Kelch_4 PF13418.1 ETO25183.1 - 0.0017 18.1 0.0 0.3 10.8 0.0 3.5 3 0 0 3 3 3 1 Galactose oxidase, central domain TPR_14 PF13428.1 ETO25183.1 - 0.0037 17.7 0.0 1.2 9.9 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_3 PF07720.7 ETO25183.1 - 0.0098 15.6 19.4 1 9.2 0.2 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat Kelch_1 PF01344.20 ETO25183.1 - 0.022 14.3 8.1 3.1 7.4 0.1 5.2 6 0 0 6 6 6 0 Kelch motif Kelch_2 PF07646.10 ETO25183.1 - 1.2 9.0 3.6 12 5.8 0.0 3.9 4 0 0 4 4 3 0 Kelch motif Sel1 PF08238.7 ETO25183.1 - 2.4 8.9 3.7 7.1 7.4 0.1 3.0 3 0 0 3 3 2 0 Sel1 repeat WD40 PF00400.27 ETO25184.1 - 4.3e-73 238.8 14.9 2.4e-13 49.3 0.0 7.0 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO25184.1 - 9.3e-15 54.8 1.8 1.1e-05 25.3 0.0 4.0 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO25184.1 - 4.4e-13 48.2 8.0 0.0044 15.2 0.4 4.6 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO25184.1 - 8.5e-11 40.7 1.4 0.0045 15.3 0.1 4.0 2 1 2 4 4 4 3 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO25184.1 - 3.6e-07 29.2 5.6 0.096 11.4 0.3 4.2 1 1 2 3 3 3 3 Nup133 N terminal like PQQ_2 PF13360.1 ETO25184.1 - 0.001 18.5 1.2 0.096 12.1 0.8 2.8 1 1 0 1 1 1 1 PQQ-like domain Nbas_N PF15492.1 ETO25184.1 - 0.0012 18.0 0.5 11 5.0 0.0 4.0 1 1 3 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Ribosomal_L21p PF00829.16 ETO25184.1 - 0.0012 18.9 0.0 4.1 7.5 0.1 4.1 4 0 0 4 4 4 1 Ribosomal prokaryotic L21 protein YTH PF04146.10 ETO25184.1 - 0.013 15.1 0.1 0.15 11.6 0.0 2.6 2 1 1 3 3 3 0 YT521-B-like domain DUF1258 PF06869.7 ETO25184.1 - 0.024 13.7 2.5 5.1 6.0 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1258) PLD_C PF12357.3 ETO25184.1 - 0.032 13.7 0.0 16 5.1 0.0 3.9 4 0 0 4 4 4 0 Phospholipase D C terminal Str_synth PF03088.11 ETO25184.1 - 0.058 13.4 0.4 26 4.9 0.0 3.5 3 1 2 5 5 5 0 Strictosidine synthase PD40 PF07676.7 ETO25184.1 - 0.18 11.5 2.5 49 3.7 0.0 4.3 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Kelch_6 PF13964.1 ETO25185.1 - 1.9e-11 43.6 5.1 1.2e-05 25.2 1.2 4.0 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 ETO25185.1 - 2.4e-09 36.5 2.5 0.00047 19.8 0.1 4.7 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.1 ETO25185.1 - 8.3e-09 35.0 0.7 0.00015 21.4 0.1 4.3 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO25185.1 - 1.3e-07 31.4 6.4 0.044 13.7 2.8 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 ETO25185.1 - 1.3e-06 28.4 0.2 0.0017 18.4 0.0 3.5 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO25185.1 - 1.5e-06 27.6 9.1 7.4e-05 22.2 0.8 4.4 5 0 0 5 5 5 1 Kelch motif YfkD PF14167.1 ETO25185.1 - 0.093 11.7 0.0 0.2 10.6 0.0 1.5 1 0 0 1 1 1 0 YfkD-like protein TMEM151 PF14857.1 ETO25187.1 - 1.3e-08 33.9 0.2 1.8e-08 33.4 0.1 1.1 1 0 0 1 1 1 1 TMEM151 family TMEM156 PF15106.1 ETO25188.1 - 0.025 13.8 0.1 0.032 13.4 0.1 1.2 1 0 0 1 1 1 0 TMEM156 protein family DUF1673 PF07895.6 ETO25188.1 - 0.026 14.0 0.2 0.04 13.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Acyl-CoA_dh_M PF02770.14 ETO25189.1 - 0.7 9.4 3.6 0.75 9.3 0.1 2.8 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase, middle domain RGS PF00615.14 ETO25190.1 - 2.3e-09 37.3 0.2 5.2e-09 36.2 0.1 1.6 1 1 0 1 1 1 1 Regulator of G protein signaling domain Secretin_N_2 PF07655.8 ETO25190.1 - 1.3 9.4 7.8 2.2 8.6 5.4 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain ERM PF00769.14 ETO25191.1 - 0.0007 19.1 20.6 0.0012 18.4 14.3 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Kelch_3 PF13415.1 ETO25191.1 - 0.088 12.9 0.2 0.43 10.8 0.0 2.2 2 0 0 2 2 2 0 Galactose oxidase, central domain THRAP3_BCLAF1 PF15440.1 ETO25191.1 - 0.38 9.3 26.4 0.55 8.8 18.3 1.2 1 0 0 1 1 1 0 THRAP3/BCLAF1 family CCDC155 PF14662.1 ETO25191.1 - 0.58 9.7 18.3 1 8.9 12.7 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 Gly_transf_sug PF04488.10 ETO25192.1 - 0.016 15.5 0.0 0.029 14.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase sugar-binding region containing DXD motif Kelch_1 PF01344.20 ETO25194.1 - 3.1e-07 29.8 2.1 0.11 12.0 0.6 4.0 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETO25194.1 - 7.3e-05 22.4 0.5 0.042 13.6 0.0 4.0 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO25194.1 - 9e-05 22.0 5.2 0.014 15.1 0.2 4.1 4 1 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO25194.1 - 0.00036 20.5 4.5 0.78 10.0 0.1 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO25194.1 - 0.001 19.1 0.1 0.049 13.8 0.0 2.9 3 0 0 3 3 3 1 Galactose oxidase, central domain DUF2781 PF10914.3 ETO25195.1 - 0.27 11.0 1.6 0.51 10.0 1.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2781) DUF4348 PF14254.1 ETO25196.1 - 0.02 14.0 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4348) DUF2407_C PF13373.1 ETO25196.1 - 0.093 12.6 0.3 0.18 11.7 0.0 1.7 1 1 0 1 1 1 0 DUF2407 C-terminal domain Rota_NS6 PF04866.7 ETO25196.1 - 0.72 9.8 6.3 0.25 11.3 2.1 2.0 1 1 1 2 2 2 0 Rotavirus non-structural protein 6 zf-C3HC4_3 PF13920.1 ETO25198.1 - 2.9e-09 36.4 10.2 5.4e-09 35.5 7.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO25198.1 - 2.8e-05 24.0 11.3 6e-05 22.9 7.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO25198.1 - 0.0034 17.0 10.7 0.0069 16.0 7.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain SDA1 PF05285.7 ETO25198.1 - 0.0061 15.8 18.0 0.0078 15.5 12.4 1.3 1 0 0 1 1 1 1 SDA1 zf-RING_2 PF13639.1 ETO25198.1 - 0.029 14.1 9.2 0.061 13.1 6.4 1.6 1 0 0 1 1 1 0 Ring finger domain CDC27 PF09507.5 ETO25198.1 - 0.029 13.6 24.2 0.036 13.2 16.8 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 LETM1 PF07766.8 ETO25198.1 - 0.062 12.3 0.5 0.13 11.3 0.3 1.5 1 0 0 1 1 1 0 LETM1-like protein CDC45 PF02724.9 ETO25198.1 - 0.082 10.9 18.7 0.11 10.5 13.0 1.3 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.7 ETO25198.1 - 0.097 12.5 12.0 0.14 12.0 8.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop14 PF04147.7 ETO25198.1 - 0.1 10.4 22.6 0.13 10.1 15.7 1.1 1 0 0 1 1 1 0 Nop14-like family eIF-3c_N PF05470.7 ETO25198.1 - 0.21 9.6 15.9 0.3 9.1 11.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Ycf1 PF05758.7 ETO25198.1 - 0.23 9.1 8.5 0.26 8.9 5.9 1.2 1 0 0 1 1 1 0 Ycf1 Trypan_PARP PF05887.6 ETO25198.1 - 0.27 11.0 18.8 0.54 10.0 13.1 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Prok-RING_4 PF14447.1 ETO25198.1 - 0.35 10.4 7.2 0.73 9.4 5.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.20 ETO25198.1 - 0.69 9.6 10.1 2.2 8.0 7.0 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3381 PF11861.3 ETO25198.1 - 1 8.8 20.2 1.9 7.9 14.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Tnp_zf-ribbon_2 PF13842.1 ETO25198.1 - 1.8 9.0 9.3 1.5 9.2 2.3 2.6 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Zip PF02535.17 ETO25198.1 - 2.6 6.9 4.5 3.3 6.6 3.1 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter SprA-related PF12118.3 ETO25198.1 - 2.9 7.1 23.7 0.38 10.0 13.7 1.5 2 0 0 2 2 2 0 SprA-related family Daxx PF03344.10 ETO25198.1 - 4.5 5.6 32.2 1.2 7.5 20.1 1.5 1 1 0 1 1 1 0 Daxx Family AAA_23 PF13476.1 ETO25198.1 - 8.5 6.6 18.9 2.4 8.4 8.5 2.1 2 0 0 2 2 2 0 AAA domain FeoC PF09012.5 ETO25200.1 - 0.54 10.0 2.7 0.25 11.0 0.1 1.7 2 0 0 2 2 2 0 FeoC like transcriptional regulator DUF755 PF05501.6 ETO25200.1 - 0.74 9.8 7.5 0.33 11.0 1.4 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF755) Thioredoxin_2 PF13098.1 ETO25201.1 - 0.094 12.9 0.4 0.33 11.1 0.1 2.0 1 1 1 2 2 2 0 Thioredoxin-like domain Arf PF00025.16 ETO25202.1 - 1.7e-06 27.4 0.0 4.5e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.1 ETO25202.1 - 0.0064 16.4 0.1 0.01 15.8 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain Paf1 PF03985.8 ETO25202.1 - 0.034 12.8 26.0 0.042 12.6 18.0 1.1 1 0 0 1 1 1 0 Paf1 MMR_HSR1 PF01926.18 ETO25202.1 - 0.29 11.0 2.3 0.65 9.9 1.3 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.1 ETO25202.1 - 2 8.6 30.1 6.2 7.1 20.8 1.6 1 1 0 1 1 1 0 AAA domain Med8 PF10232.4 ETO25202.1 - 2.5 7.5 16.5 3.3 7.1 11.5 1.1 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 AAA_17 PF13207.1 ETO25202.1 - 2.7 8.8 6.1 4.3 8.1 4.2 1.4 1 1 0 1 1 1 0 AAA domain Tankyrase_bdg_C PF15327.1 ETO25202.1 - 4.1 7.5 16.1 0.34 11.0 6.3 2.0 1 1 1 2 2 2 0 Tankyrase binding protein C terminal domain Miro PF08477.8 ETO25202.1 - 5.3 7.5 7.9 1.5 9.3 0.1 2.6 1 1 2 3 3 3 0 Miro-like protein BTV_NS2 PF04514.7 ETO25202.1 - 6.9 5.4 23.0 8.7 5.1 16.0 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF4551 PF15087.1 ETO25202.1 - 7 4.8 12.6 8.1 4.6 8.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Tic20 PF09685.5 ETO25203.1 - 0.49 10.3 8.0 0.94 9.4 1.5 2.3 2 0 0 2 2 2 0 Tic20-like protein WBP-1 PF11669.3 ETO25203.1 - 3.1 7.9 10.3 0.41 10.7 0.7 2.5 2 0 0 2 2 2 0 WW domain-binding protein 1 WD40 PF00400.27 ETO25205.1 - 6.4e-12 44.8 0.0 1.3e-10 40.7 0.0 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat NAD_binding_1 PF00175.16 ETO25206.1 - 2.8e-11 43.9 0.1 0.00015 22.2 0.2 2.3 1 1 1 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 ETO25206.1 - 2e-08 34.2 0.2 3.8e-08 33.3 0.2 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain IncFII_repA PF02387.10 ETO25206.1 - 0.027 13.6 0.5 0.041 13.0 0.3 1.2 1 0 0 1 1 1 0 IncFII RepA protein family 7tm_1 PF00001.16 ETO25206.1 - 0.063 12.4 0.4 0.1 11.7 0.3 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) EF-hand_9 PF14658.1 ETO25207.1 - 3.1e-05 23.8 0.0 0.059 13.3 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.1 ETO25207.1 - 0.0012 18.5 0.0 3.5 7.7 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 ETO25207.1 - 0.013 14.7 0.0 12 5.4 0.0 3.7 4 0 0 4 4 4 0 EF hand DUF1869 PF08956.5 ETO25207.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1869) Bap31 PF05529.7 ETO25208.1 - 0.00014 21.3 4.7 0.00031 20.2 3.3 1.5 1 1 0 1 1 1 1 B-cell receptor-associated protein 31-like Takusan PF04822.8 ETO25208.1 - 0.0058 16.3 0.3 0.012 15.3 0.2 1.5 1 0 0 1 1 1 1 Takusan LCAT PF02450.10 ETO25208.1 - 0.052 12.5 0.1 0.095 11.6 0.1 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF3365 PF11845.3 ETO25208.1 - 0.088 12.6 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) APG6 PF04111.7 ETO25208.1 - 0.19 10.7 7.1 0.24 10.4 4.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 V-SNARE PF05008.10 ETO25208.1 - 3.1 8.0 8.3 1.4 9.1 2.9 2.2 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DivIC PF04977.10 ETO25208.1 - 5.3 6.6 6.1 11 5.5 0.1 2.9 2 1 1 3 3 3 0 Septum formation initiator Nop14 PF04147.7 ETO25209.1 - 0.0012 16.9 24.3 0.0012 16.9 16.8 1.5 2 0 0 2 2 2 1 Nop14-like family Kelch_2 PF07646.10 ETO25211.1 - 1.7e-06 27.5 1.1 0.0013 18.4 0.2 4.2 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.20 ETO25211.1 - 3.6e-06 26.4 3.0 0.0014 18.0 0.5 4.4 5 0 0 5 5 5 1 Kelch motif Kelch_6 PF13964.1 ETO25211.1 - 0.00024 21.1 3.5 0.15 12.2 0.3 3.8 3 1 1 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO25211.1 - 0.0015 18.2 0.6 0.61 9.9 0.0 3.8 3 1 1 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO25211.1 - 0.0019 18.0 0.6 0.54 10.2 0.2 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 ETO25211.1 - 0.024 14.7 0.0 0.55 10.4 0.0 3.2 4 0 0 4 4 4 0 Galactose oxidase, central domain DUF327 PF03885.8 ETO25212.1 - 0.13 12.1 3.6 0.2 11.4 1.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF327) WD40 PF00400.27 ETO25213.1 - 1.1e-45 151.9 19.9 7e-11 41.5 0.0 5.6 5 1 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO25213.1 - 2.8e-07 29.0 3.8 0.056 11.5 0.0 4.3 2 2 2 4 4 4 4 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO25213.1 - 1.6e-06 28.3 3.2 1.6e-06 28.3 2.2 4.2 3 1 2 5 5 5 1 TRAF-type zinc finger DUF4470 PF14737.1 ETO25214.1 - 0.0024 17.5 0.4 0.009 15.7 0.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4470) DUF3548 PF12068.3 ETO25214.1 - 0.16 11.2 1.4 0.32 10.2 0.0 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3548) RRM_1 PF00076.17 ETO25215.1 - 1.1e-08 34.6 0.0 3.6e-08 32.9 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO25215.1 - 2.7e-07 30.3 0.0 4.1e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO25215.1 - 8.1e-07 28.9 0.0 1.5e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 ETO25215.1 - 0.0008 19.0 1.2 0.0014 18.2 0.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Vfa1 PF08432.5 ETO25215.1 - 0.0095 15.9 1.3 0.015 15.3 0.9 1.3 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Nup35_RRM_2 PF14605.1 ETO25215.1 - 0.099 12.4 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Cyt-b5 PF00173.23 ETO25216.1 - 4.1e-06 26.4 0.0 5.8e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ABC2_membrane_3 PF12698.2 ETO25217.1 - 5.1e-15 55.3 12.9 7.5e-15 54.7 9.0 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein Flavodoxin_1 PF00258.20 ETO25217.1 - 0.12 12.3 0.0 0.34 10.8 0.0 1.8 1 0 0 1 1 1 0 Flavodoxin Adap_comp_sub PF00928.16 ETO25219.1 - 3.8e-14 52.4 0.4 1.5e-08 34.1 0.0 2.1 2 0 0 2 2 2 2 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 ETO25219.1 - 1.6e-05 24.6 3.6 4.5e-05 23.2 1.5 2.4 2 1 0 2 2 2 1 Clathrin adaptor complex small chain Baculo_E56 PF04639.7 ETO25219.1 - 0.11 11.1 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope Adap_comp_sub PF00928.16 ETO25220.1 - 1.4e-50 171.8 0.2 1.6e-50 171.6 0.2 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Lipase_3 PF01764.20 ETO25221.1 - 4.9e-11 42.4 0.0 1.5e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 Lipase (class 3) Menin PF05053.8 ETO25221.1 - 0.11 10.5 1.7 0.19 9.8 1.2 1.2 1 0 0 1 1 1 0 Menin Kelch_6 PF13964.1 ETO25222.1 - 1.1e-08 34.8 2.6 0.0069 16.5 0.4 3.9 2 1 1 3 3 3 2 Kelch motif Kelch_5 PF13854.1 ETO25222.1 - 7.7e-07 28.9 5.0 0.092 12.7 1.6 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 ETO25222.1 - 8.7e-06 25.7 2.2 0.0019 18.3 0.0 3.7 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO25222.1 - 9.1e-06 25.1 3.8 0.026 14.0 0.3 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 ETO25222.1 - 0.00039 20.0 0.9 0.13 12.0 0.0 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETO25222.1 - 0.031 14.0 1.8 1.2 8.9 0.1 3.5 4 0 0 4 4 4 0 Galactose oxidase, central domain DUF221 PF02714.10 ETO25223.1 - 1.1e-20 73.7 12.0 3.6e-20 72.0 8.3 1.7 1 1 0 1 1 1 1 Domain of unknown function DUF221 Dscam_C PF12355.3 ETO25224.1 - 0.061 13.6 2.7 0.12 12.6 1.8 1.5 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal Cag12 PF13117.1 ETO25224.1 - 0.07 13.0 9.9 0.89 9.4 0.3 2.5 1 1 1 2 2 2 0 Cag pathogenicity island protein Cag12 FAM131 PF15010.1 ETO25224.1 - 1.6 8.4 7.1 2 8.1 4.9 1.1 1 0 0 1 1 1 0 Putative cell signalling WWE PF02825.15 ETO25225.1 - 6.4e-05 22.2 0.3 0.00022 20.5 0.2 1.9 1 0 0 1 1 1 1 WWE domain MIP-T3 PF10243.4 ETO25225.1 - 0.0016 17.0 60.3 0.0016 17.0 41.8 2.2 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 Imm19 PF15567.1 ETO25226.1 - 0.14 12.1 2.3 34 4.5 0.0 3.4 3 1 0 3 3 3 0 Immunity protein 19 Myb_DNA-binding PF00249.26 ETO25226.1 - 0.24 11.4 2.0 38 4.4 0.0 3.2 3 0 0 3 3 3 0 Myb-like DNA-binding domain DUF4285 PF14113.1 ETO25226.1 - 0.41 10.6 6.3 1.8 8.5 0.5 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4285) COPI_C PF06957.6 ETO25226.1 - 0.44 9.0 11.9 1.2 7.5 0.4 2.2 1 1 1 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus ChaB PF06150.7 ETO25226.1 - 1.9 8.3 6.8 1.4 8.7 0.1 3.6 4 0 0 4 4 4 0 ChaB Serglycin PF04360.7 ETO25227.1 - 0.33 10.6 10.3 0.77 9.4 7.2 1.7 1 1 0 1 1 1 0 Serglycin DUF2360 PF10152.4 ETO25228.1 - 2.4e-13 50.6 0.2 3.7e-13 49.9 0.2 1.3 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) TatD_DNase PF01026.16 ETO25229.1 - 3.4e-51 173.9 0.0 4.9e-51 173.3 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 ETO25229.1 - 0.002 17.7 0.0 0.018 14.6 0.0 2.3 2 1 1 3 3 3 1 Amidohydrolase TRA-1_regulated PF02343.11 ETO25229.1 - 0.01 15.3 0.2 0.019 14.4 0.1 1.4 1 0 0 1 1 1 0 TRA-1 regulated protein R03H10.4 SNARE_assoc PF09335.6 ETO25230.1 - 7e-11 42.3 4.5 7e-11 42.3 3.1 2.2 2 0 0 2 2 2 1 SNARE associated Golgi protein SP_C-Propep PF08999.5 ETO25230.1 - 0.008 15.6 2.2 0.008 15.6 1.5 2.7 3 1 0 3 3 3 1 Surfactant protein C, N terminal propeptide TatD_DNase PF01026.16 ETO25231.1 - 6.2e-52 176.3 0.0 7.5e-52 176.0 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 ETO25231.1 - 0.0021 17.6 0.0 0.012 15.2 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase Kelch_6 PF13964.1 ETO25233.1 - 1.1e-10 41.1 3.0 2.6e-05 24.2 0.4 4.3 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO25233.1 - 2.1e-07 30.3 1.6 2.2e-05 23.8 0.1 3.7 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 ETO25233.1 - 2.8e-07 30.5 0.1 3.1e-05 23.9 0.0 3.5 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO25233.1 - 6e-07 29.1 0.9 1.9e-05 24.2 0.1 3.1 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO25233.1 - 2.8e-05 23.7 0.7 0.056 13.2 0.2 4.3 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 ETO25233.1 - 0.00016 21.5 1.0 0.019 14.8 1.6 3.0 3 0 0 3 3 3 1 Kelch motif BTB PF00651.26 ETO25234.1 - 1.8e-06 27.9 1.4 4.8e-06 26.5 1.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain DUF3342 PF11822.3 ETO25234.1 - 0.036 13.2 1.3 0.052 12.6 0.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3342) Ras PF00071.17 ETO25235.1 - 1.3e-26 92.9 0.0 1.5e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO25235.1 - 4.4e-10 40.0 0.0 6.4e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 ETO25235.1 - 6.4e-09 35.5 0.0 1.1e-05 24.9 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain SRPRB PF09439.5 ETO25235.1 - 1.7e-05 24.1 0.0 3.8e-05 22.9 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Arf PF00025.16 ETO25235.1 - 5.5e-05 22.4 0.0 7.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETO25235.1 - 0.00039 19.6 0.0 0.00046 19.3 0.0 1.2 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 ETO25235.1 - 0.00081 19.3 0.0 0.0011 18.9 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF3627 PF12299.3 ETO25235.1 - 0.011 15.7 0.2 0.018 15.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3627) PduV-EutP PF10662.4 ETO25235.1 - 0.021 14.3 0.0 0.038 13.4 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 ETO25235.1 - 0.034 13.6 0.0 0.21 11.1 0.0 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein CheR PF01739.13 ETO25235.1 - 0.036 13.3 0.1 0.053 12.7 0.1 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain G-alpha PF00503.15 ETO25235.1 - 0.051 12.2 0.2 0.077 11.6 0.0 1.5 1 1 1 2 2 2 0 G-protein alpha subunit MobB PF03205.9 ETO25235.1 - 0.14 11.8 0.0 0.52 10.0 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DLIC PF05783.6 ETO25235.1 - 0.14 10.8 1.1 4.6 5.7 0.6 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) WD40 PF00400.27 ETO25236.1 - 8.8e-53 174.4 19.4 1.9e-10 40.1 0.2 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO25236.1 - 9.1e-11 40.5 8.5 0.0046 15.1 0.1 5.4 2 2 2 5 5 5 4 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO25236.1 - 0.00023 20.8 2.5 0.012 15.3 0.1 3.7 2 2 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Aegerolysin PF06355.8 ETO25236.1 - 0.0046 16.8 1.3 0.0046 16.8 0.9 2.2 2 0 0 2 2 2 1 Aegerolysin zf-C3HC4_2 PF13923.1 ETO25236.1 - 1.2 9.2 7.8 0.26 11.3 0.2 3.5 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) YpzI PF14140.1 ETO25237.1 - 0.13 11.7 0.6 0.13 11.7 0.4 2.3 2 1 0 2 2 2 0 YpzI-like protein Presenilin PF01080.12 ETO25237.1 - 4.2 6.0 8.2 4.4 6.0 5.7 1.0 1 0 0 1 1 1 0 Presenilin CaMBD PF02888.11 ETO25238.1 - 0.053 13.3 0.5 0.053 13.3 0.4 2.3 2 1 0 2 2 2 0 Calmodulin binding domain DUF1664 PF07889.7 ETO25238.1 - 0.39 10.5 5.6 0.79 9.5 3.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4436 PF14494.1 ETO25238.1 - 0.47 9.7 5.5 0.59 9.3 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) DUF1980 PF09323.5 ETO25238.1 - 1.9 8.1 8.2 2.7 7.6 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Slu7 PF11708.3 ETO25238.1 - 2.1 8.0 12.1 6.7 6.3 8.5 1.6 1 1 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor RRM_5 PF13893.1 ETO25239.1 - 0.00026 20.7 0.7 0.00071 19.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO25239.1 - 0.018 14.6 0.0 0.055 13.1 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO25239.1 - 0.049 13.6 0.0 0.25 11.3 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) APC_CDC26 PF10471.4 ETO25239.1 - 9.3 7.0 21.9 0.09 13.5 6.1 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 DUF1910 PF08928.5 ETO25240.1 - 0.02 14.8 2.0 0.061 13.3 1.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) Sigma70_ner PF04546.8 ETO25240.1 - 1.3 8.6 20.2 0.16 11.5 5.4 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region RXT2_N PF08595.6 ETO25240.1 - 1.5 8.6 13.4 4.1 7.1 3.5 2.8 2 0 0 2 2 2 0 RXT2-like, N-terminal Prothymosin PF03247.9 ETO25240.1 - 1.5 9.0 32.7 0.48 10.5 3.4 2.4 2 0 0 2 2 2 0 Prothymosin/parathymosin family CENP-B_dimeris PF09026.5 ETO25240.1 - 1.7 8.9 27.2 3.2 8.0 7.0 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PH PF00169.24 ETO25241.1 - 0.022 14.9 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 PH domain RRM_6 PF14259.1 ETO25242.1 - 0.0018 18.1 0.0 4.5 7.3 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO25242.1 - 0.0021 17.6 0.1 2.5 7.7 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OST-HTH PF12872.2 ETO25242.1 - 0.0095 15.7 0.0 4 7.3 0.0 2.8 2 0 0 2 2 2 2 OST-HTH/LOTUS domain DEK_C PF08766.6 ETO25242.1 - 0.16 11.7 0.6 23 4.8 0.0 3.2 3 0 0 3 3 3 0 DEK C terminal domain BaffR-Tall_bind PF09256.5 ETO25242.1 - 0.48 10.0 3.5 0.54 9.8 1.3 1.9 2 0 0 2 2 2 0 BAFF-R, TALL-1 binding SH3_1 PF00018.23 ETO25243.1 - 1.4e-08 33.9 0.1 4.2e-07 29.2 0.0 2.4 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 ETO25243.1 - 2.7e-05 23.6 0.1 5.7e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 ETO25243.1 - 6.2e-05 22.4 0.0 0.00014 21.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Nup35_RRM PF05172.8 ETO25243.1 - 0.017 14.8 1.2 0.34 10.6 0.0 2.9 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif SH3_3 PF08239.6 ETO25243.1 - 0.023 14.9 0.1 0.48 10.6 0.1 2.4 2 0 0 2 2 2 0 Bacterial SH3 domain RRM_1 PF00076.17 ETO25243.1 - 0.024 14.2 0.0 0.064 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO25243.1 - 0.033 14.1 0.0 0.088 12.7 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Sulfotransfer_2 PF03567.9 ETO25245.1 - 1.9e-14 53.9 1.5 1.9e-14 53.9 1.0 1.5 2 0 0 2 2 2 1 Sulfotransferase family DUF2892 PF11127.3 ETO25246.1 - 0.21 11.4 3.6 0.096 12.5 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) HMG_box PF00505.14 ETO25247.1 - 2.6e-22 78.8 7.7 2.6e-22 78.8 5.3 2.8 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 ETO25247.1 - 2e-15 56.8 6.4 2e-15 56.8 4.4 3.0 3 1 0 3 3 3 1 HMG-box domain SAPS PF04499.10 ETO25247.1 - 0.67 8.5 14.9 0.68 8.4 10.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Dus PF01207.12 ETO25247.1 - 2.3 6.9 5.3 3.2 6.4 3.7 1.2 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Nop14 PF04147.7 ETO25247.1 - 3.7 5.3 36.5 4.1 5.1 25.3 1.0 1 0 0 1 1 1 0 Nop14-like family RA PF00788.18 ETO25248.1 - 0.047 14.1 0.0 0.21 12.0 0.0 2.0 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain ORF6N PF10543.4 ETO25248.1 - 0.071 13.1 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 ORF6N domain PAS_10 PF13596.1 ETO25248.1 - 0.23 11.7 3.1 3 8.1 0.3 2.4 2 0 0 2 2 2 0 PAS domain HEAT PF02985.17 ETO25250.1 - 2.1e-08 33.5 1.1 0.61 10.3 0.2 4.6 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.1 ETO25250.1 - 0.00049 20.3 0.9 0.096 12.9 0.2 2.8 2 1 1 3 3 3 3 HEAT repeats DAGAT PF03982.8 ETO25251.1 - 3.4e-23 81.8 0.3 6.3e-18 64.4 0.0 2.1 2 0 0 2 2 2 2 Diacylglycerol acyltransferase Toxin_8 PF07365.7 ETO25251.1 - 0.31 11.0 1.6 0.54 10.2 1.1 1.4 1 0 0 1 1 1 0 Alpha conotoxin precursor WD40 PF00400.27 ETO25252.1 - 2.3e-66 217.4 28.5 2.9e-12 45.9 0.9 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO25252.1 - 9.3e-13 47.1 9.6 0.00038 18.7 0.0 5.8 2 2 2 5 5 5 5 Nucleoporin Nup120/160 PI3K_C2 PF00792.19 ETO25252.1 - 0.035 13.8 0.0 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 FMO-like PF00743.14 ETO25253.1 - 5e-14 51.4 0.0 1.1e-12 47.0 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 ETO25253.1 - 1.7e-09 38.0 0.0 4.2e-09 36.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETO25253.1 - 3.1e-06 26.3 0.0 9e-05 21.5 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 ETO25253.1 - 0.00028 20.8 0.0 0.0019 18.0 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETO25253.1 - 0.0039 17.5 0.0 0.0082 16.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 ETO25253.1 - 0.0064 15.3 0.1 0.55 9.0 0.0 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A ThiF PF00899.16 ETO25253.1 - 0.019 14.8 0.0 0.052 13.3 0.0 1.7 2 0 0 2 2 2 0 ThiF family NAD_binding_7 PF13241.1 ETO25253.1 - 0.029 14.6 0.0 0.069 13.4 0.0 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 ETO25253.1 - 0.029 14.4 0.0 0.062 13.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 ETO25253.1 - 0.065 12.6 0.0 0.16 11.4 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DAO PF01266.19 ETO25253.1 - 0.16 10.8 0.0 0.99 8.2 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase FimP PF09766.4 ETO25253.1 - 0.2 10.6 7.6 0.29 10.1 5.3 1.1 1 0 0 1 1 1 0 Fms-interacting protein Secretin_N_2 PF07655.8 ETO25253.1 - 0.35 11.2 20.2 0.62 10.4 14.0 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain DUF912 PF06024.7 ETO25253.1 - 2.7 8.0 10.3 5 7.2 7.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Daxx PF03344.10 ETO25254.1 - 0.048 12.1 20.1 0.074 11.5 13.9 1.2 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 ETO25254.1 - 0.052 12.6 20.7 0.13 11.2 14.3 1.6 1 0 0 1 1 1 0 BUD22 Deltaretro_Tax PF05599.6 ETO25254.1 - 0.12 12.7 0.0 0.64 10.3 0.0 2.2 3 0 0 3 3 3 0 Deltaretrovirus Tax protein RRM_6 PF14259.1 ETO25255.1 - 2.3e-08 33.8 0.0 4.3e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO25255.1 - 1.4e-06 27.8 0.0 1.1e-05 24.8 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 ETO25255.1 - 1.8e-05 24.4 2.9 1.8e-05 24.4 2.0 2.0 2 0 0 2 2 2 1 Zinc knuckle RRM_5 PF13893.1 ETO25255.1 - 0.00063 19.5 0.0 0.0018 18.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_6 PF15288.1 ETO25255.1 - 0.0032 17.0 1.6 0.0032 17.0 1.1 2.2 3 0 0 3 3 2 1 Zinc knuckle zf-RanBP PF00641.13 ETO25255.1 - 0.0075 15.3 14.2 0.0075 15.3 9.9 1.7 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-CCHC_4 PF14392.1 ETO25255.1 - 0.019 14.6 0.5 0.019 14.6 0.4 1.9 2 0 0 2 2 1 0 Zinc knuckle Pox_Ag35 PF03286.9 ETO25255.1 - 0.027 14.0 5.0 0.041 13.3 3.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Foamy_BEL PF03274.9 ETO25255.1 - 0.039 13.1 1.7 0.068 12.3 1.2 1.4 1 0 0 1 1 1 0 Foamy virus BEL 1/2 protein MRP-L46 PF11788.3 ETO25255.1 - 0.044 14.4 2.1 0.11 13.1 1.5 1.6 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 Auxin_inducible PF02519.9 ETO25255.1 - 0.088 12.8 0.2 0.19 11.7 0.2 1.5 1 0 0 1 1 1 0 Auxin responsive protein zf-Paramyx-P PF13008.2 ETO25255.1 - 6.4 6.0 14.8 0.26 10.4 5.4 2.1 2 0 0 2 2 2 0 Zinc-binding domain of Paramyxoviridae V protein zf-RanBP PF00641.13 ETO25256.1 - 3.5e-05 22.8 6.0 6.3e-05 21.9 4.2 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF4414 PF14377.1 ETO25256.1 - 3.1 7.7 10.3 7.9 6.4 7.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4414) CAML PF14963.1 ETO25257.1 - 0.9 8.8 3.4 0.98 8.7 2.4 1.0 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Apis_Csd PF11671.3 ETO25257.1 - 8.5 6.1 11.9 12 5.7 8.2 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein Nipped-B_C PF12830.2 ETO25258.1 - 3.8e-08 33.1 0.2 1.9e-07 30.9 0.0 2.3 2 1 0 2 2 2 1 Sister chromatid cohesion C-terminus Peptidase_C48 PF02902.14 ETO25259.1 - 3.2e-30 105.3 7.0 3.2e-30 105.3 4.8 2.5 3 0 0 3 3 3 1 Ulp1 protease family, C-terminal catalytic domain Cohesin_HEAT PF12765.2 ETO25260.1 - 9.6e-10 38.2 2.0 1.8e-07 30.9 0.3 2.3 2 0 0 2 2 2 2 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.1 ETO25260.1 - 3.7e-05 23.9 0.1 0.027 14.7 0.0 1.8 1 1 1 2 2 2 2 HEAT repeats Ipi1_N PF12333.3 ETO25260.1 - 0.0016 18.3 2.8 1.3 9.0 0.0 3.3 2 1 2 4 4 4 2 Rix1 complex component involved in 60S ribosome maturation Cnd1 PF12717.2 ETO25260.1 - 0.072 12.9 0.9 3.3 7.5 0.0 2.9 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 ETO25260.1 - 0.094 12.8 0.0 2.9 8.2 0.0 3.0 3 0 0 3 3 3 0 HEAT repeat DUF2435 PF10363.4 ETO25260.1 - 0.21 11.5 1.0 11 5.9 0.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2435) WD40 PF00400.27 ETO25262.1 - 6.4e-36 120.9 14.4 3.2e-11 42.6 0.1 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO25262.1 - 0.0046 15.1 0.2 1.1 7.2 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 AAA PF00004.24 ETO25264.1 - 6.2e-42 142.9 0.0 9e-42 142.3 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETO25264.1 - 1.2e-08 35.2 0.3 1e-07 32.1 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 ETO25264.1 - 2.6e-08 33.2 0.0 3.8e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 ETO25264.1 - 2.2e-06 27.5 0.0 4.9e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 ETO25264.1 - 2.7e-06 26.6 0.4 3.4e-05 23.0 0.0 2.7 2 1 0 2 2 2 1 Zeta toxin AAA_2 PF07724.9 ETO25264.1 - 3.3e-06 27.1 0.0 8.3e-06 25.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 ETO25264.1 - 2.3e-05 25.1 0.1 6.2e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 ETO25264.1 - 2.6e-05 23.7 0.0 4.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 ETO25264.1 - 4.7e-05 23.5 0.2 0.0017 18.4 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETO25264.1 - 6.1e-05 22.6 0.2 0.00057 19.5 0.1 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 ETO25264.1 - 7.2e-05 22.5 0.5 0.00076 19.2 0.3 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 ETO25264.1 - 7.8e-05 22.1 1.8 0.066 12.6 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_18 PF13238.1 ETO25264.1 - 0.00026 21.2 1.2 0.0015 18.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 ETO25264.1 - 0.00031 20.6 0.0 0.00062 19.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 ETO25264.1 - 0.00053 19.6 0.4 0.022 14.4 0.0 2.2 1 1 1 2 2 2 1 NACHT domain TIP49 PF06068.8 ETO25264.1 - 0.0013 17.5 0.1 0.0037 16.0 0.0 1.7 1 1 1 2 2 2 1 TIP49 C-terminus Mg_chelatase PF01078.16 ETO25264.1 - 0.0024 17.0 0.4 0.0059 15.7 0.1 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 ETO25264.1 - 0.0048 16.8 0.0 0.01 15.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain CPT PF07931.7 ETO25264.1 - 0.013 15.1 0.1 0.055 13.0 0.0 2.0 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein RNA_helicase PF00910.17 ETO25264.1 - 0.028 14.5 0.4 0.065 13.4 0.0 2.0 2 1 0 2 2 2 0 RNA helicase ABC_tran PF00005.22 ETO25264.1 - 0.032 14.5 0.2 0.11 12.7 0.0 2.0 1 1 0 2 2 2 0 ABC transporter KaiC PF06745.8 ETO25264.1 - 0.033 13.3 0.1 0.41 9.7 0.0 2.2 1 1 0 2 2 2 0 KaiC DEAD PF00270.24 ETO25264.1 - 0.034 13.6 0.0 3.2 7.2 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase Sigma54_activ_2 PF14532.1 ETO25264.1 - 0.042 13.8 0.1 0.098 12.7 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain Viral_helicase1 PF01443.13 ETO25264.1 - 0.059 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 ETO25264.1 - 0.064 12.8 0.0 0.15 11.6 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 ETO25264.1 - 0.072 12.0 0.1 0.072 12.0 0.1 1.8 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 ETO25264.1 - 0.2 11.0 3.7 1.4 8.2 0.0 2.7 2 1 1 3 3 3 0 AAA-like domain eIF2A PF08662.6 ETO25266.1 - 4.5e-48 163.5 0.0 6e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A TLP-20 PF06088.6 ETO25266.1 - 7.3 6.2 16.6 0.039 13.6 4.2 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF1664 PF07889.7 ETO25267.1 - 3.4 7.4 25.1 1.9 8.3 2.4 4.7 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) EssA PF10661.4 ETO25268.1 - 0.014 15.0 6.8 0.016 14.8 4.7 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA YkuI_C PF10388.4 ETO25268.1 - 0.093 12.4 5.3 0.11 12.1 3.7 1.1 1 0 0 1 1 1 0 EAL-domain associated signalling protein domain DUF2393 PF09624.5 ETO25268.1 - 0.83 9.1 11.0 1.5 8.2 7.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2393) Secretogranin_V PF05281.6 ETO25268.1 - 6.3 6.1 7.7 8 5.7 5.3 1.1 1 0 0 1 1 1 0 Neuroendocrine protein 7B2 precursor (Secretogranin V) UCH PF00443.24 ETO25270.1 - 3.8e-23 81.9 0.9 5.1e-23 81.5 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO25270.1 - 8.2e-12 45.1 4.2 1.1e-05 25.0 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF3037 PF11236.3 ETO25270.1 - 0.1 12.6 0.2 0.36 10.8 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3037) LUC7 PF03194.10 ETO25270.1 - 0.21 11.1 2.4 0.76 9.2 0.6 2.4 1 1 1 2 2 2 0 LUC7 N_terminus IMS PF00817.15 ETO25273.1 - 3.7e-22 78.7 0.0 7.9e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 ETO25273.1 - 1.4e-12 47.6 1.2 7.5e-12 45.2 0.9 2.1 1 1 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 ETO25273.1 - 1.4e-07 31.0 0.1 3.6e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 IMS family HHH motif Pkinase PF00069.20 ETO25274.1 - 6.4e-26 91.0 0.1 1.3e-20 73.6 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO25274.1 - 4.2e-12 45.6 0.0 3.8e-10 39.2 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 ETO25274.1 - 0.00011 21.3 0.0 0.00021 20.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SNase PF00565.12 ETO25275.1 - 5.6e-18 65.1 10.2 3.4e-13 49.7 0.3 4.2 4 1 0 4 4 4 3 Staphylococcal nuclease homologue SNase PF00565.12 ETO25276.1 - 6.1e-19 68.2 6.9 1.5e-05 25.2 0.0 4.6 3 2 1 4 4 4 3 Staphylococcal nuclease homologue TUDOR PF00567.19 ETO25276.1 - 2.5e-18 66.0 0.0 6.4e-18 64.7 0.0 1.7 1 0 0 1 1 1 1 Tudor domain Histone PF00125.19 ETO25278.1 - 1.2e-16 60.5 0.0 1.9e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 ETO25278.1 - 0.0036 17.3 3.0 0.0043 17.0 0.1 2.4 3 0 0 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 ETO25278.1 - 0.074 13.3 0.2 0.18 12.1 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Virulence_fact PF13769.1 ETO25279.1 - 0.042 13.7 0.1 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 Virulence factor DUF4618 PF15397.1 ETO25280.1 - 0.032 13.5 2.4 0.054 12.8 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) SAM_PNT PF02198.11 ETO25280.1 - 0.032 13.9 0.1 0.072 12.8 0.1 1.6 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Pkinase PF00069.20 ETO25281.1 - 3.7e-44 150.8 0.1 4.2e-43 147.3 0.1 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO25281.1 - 1.6e-26 92.9 0.2 2.2e-20 72.8 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Mannosyl_trans3 PF11051.3 ETO25282.1 - 3.1e-07 30.0 0.0 4.4e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Imm8 PF15560.1 ETO25282.1 - 0.07 12.8 0.0 0.14 11.8 0.0 1.5 2 0 0 2 2 2 0 Immunity protein 8 B56 PF01603.15 ETO25283.1 - 6.5e-35 120.5 3.2 7.2e-35 120.3 2.2 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Katanin_con80 PF13925.1 ETO25283.1 - 0.078 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 con80 domain of Katanin Endonuc-BglII PF09195.6 ETO25283.1 - 0.082 12.3 0.6 0.12 11.8 0.4 1.2 1 0 0 1 1 1 0 Restriction endonuclease BglII Mlo PF03094.10 ETO25284.1 - 0.022 12.8 0.5 0.15 10.1 0.0 2.0 2 0 0 2 2 2 0 Mlo family Kelch_6 PF13964.1 ETO25285.1 - 1.6e-08 34.3 3.6 0.00069 19.6 0.1 3.7 3 1 1 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO25285.1 - 3.2e-05 23.5 1.5 0.035 13.8 0.1 3.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO25285.1 - 0.0065 15.9 11.9 0.062 12.8 0.1 4.1 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 ETO25285.1 - 0.028 14.3 7.1 4.8 7.2 0.4 4.2 4 0 0 4 4 4 0 Kelch motif N_Asn_amidohyd PF14736.1 ETO25285.1 - 0.071 11.9 0.2 0.16 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein N-terminal asparagine amidohydrolase Kelch_2 PF07646.10 ETO25285.1 - 0.37 10.6 4.4 20 5.1 0.1 4.2 5 0 0 5 5 5 0 Kelch motif WD40 PF00400.27 ETO25286.1 - 6.4e-72 235.0 18.0 4.2e-13 48.6 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO25286.1 - 3.5e-11 43.1 1.2 0.00041 20.0 0.0 3.5 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Resistin PF06954.6 ETO25286.1 - 3.6e-05 23.9 0.2 2.2 8.6 0.0 4.3 2 2 2 4 4 4 2 Resistin Cytochrom_D1 PF02239.11 ETO25286.1 - 9.4e-05 20.8 1.7 0.052 11.8 0.0 2.9 1 1 4 5 5 5 4 Cytochrome D1 heme domain PD40 PF07676.7 ETO25286.1 - 0.0019 17.8 14.0 2.7 7.7 0.1 6.3 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO25286.1 - 0.0037 16.7 0.1 0.32 10.4 0.0 2.6 1 1 0 2 2 2 1 PQQ-like domain DUF1513 PF07433.6 ETO25286.1 - 0.0038 16.1 0.2 7 5.4 0.0 3.5 2 1 1 4 4 4 1 Protein of unknown function (DUF1513) DPPIV_N PF00930.16 ETO25286.1 - 0.0045 15.6 0.9 3.7 6.0 0.0 4.0 1 1 4 5 5 5 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nbas_N PF15492.1 ETO25286.1 - 0.0084 15.2 0.8 1 8.4 0.0 2.9 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 ETO25286.1 - 1.9 7.9 8.9 10 5.5 0.0 4.1 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 ETO25287.1 - 1.5e-68 224.4 20.9 1.2e-13 50.3 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO25287.1 - 4.3e-09 36.3 0.1 0.00012 21.8 0.0 3.6 1 1 4 5 5 5 3 Eukaryotic translation initiation factor eIF2A Str_synth PF03088.11 ETO25287.1 - 6.4e-05 22.9 0.1 4.4 7.4 0.0 4.7 3 2 2 5 5 5 1 Strictosidine synthase Nbas_N PF15492.1 ETO25287.1 - 0.00013 21.1 2.3 6.9 5.6 0.0 4.7 1 1 4 5 5 5 2 Neuroblastoma-amplified sequence, N terminal MMS1_N PF10433.4 ETO25287.1 - 0.00033 18.9 0.1 2 6.4 0.0 3.8 1 1 2 4 4 4 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term PD40 PF07676.7 ETO25287.1 - 0.0017 17.9 15.8 3.6 7.3 0.0 6.7 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO25287.1 - 0.0035 15.7 0.0 0.3 9.3 0.0 2.4 1 1 1 2 2 2 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO25287.1 - 0.0052 15.5 3.5 1.1 7.9 0.1 3.3 1 1 2 3 3 3 1 Nup133 N terminal like Hira PF07569.6 ETO25287.1 - 0.029 13.5 0.3 12 5.0 0.0 3.3 1 1 1 3 3 3 0 TUP1-like enhancer of split Proteasome_A_N PF10584.4 ETO25287.1 - 0.075 12.3 19.9 1 8.7 0.0 6.6 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature NodS PF05401.6 ETO25287.1 - 0.1 11.9 0.0 5 6.4 0.0 3.1 3 1 1 4 4 4 0 Nodulation protein S (NodS) Resistin PF06954.6 ETO25287.1 - 0.37 11.0 2.3 57 4.0 0.0 4.0 1 1 4 5 5 5 0 Resistin DUF2911 PF11138.3 ETO25288.1 - 0.4 10.3 2.4 0.39 10.3 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2911) Selenoprotein_S PF06936.6 ETO25288.1 - 6.1 6.3 9.0 0.52 9.8 2.5 1.9 1 1 0 1 1 1 0 Selenoprotein S (SelS) MIF4G PF02854.14 ETO25289.1 - 1.1e-08 34.7 3.2 2.7e-08 33.5 2.2 1.7 1 1 0 1 1 1 1 MIF4G domain Replic_Relax PF13814.1 ETO25289.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Replication-relaxation DUF3508 PF12018.3 ETO25289.1 - 0.029 13.3 1.4 0.069 12.1 0.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3508) Bclx_interact PF08945.5 ETO25289.1 - 0.49 9.9 1.7 1.2 8.7 1.2 1.6 1 0 0 1 1 1 0 Bcl-x interacting, BH3 domain Elongin_A PF06881.6 ETO25291.1 - 2.7 8.4 10.4 0.81 10.1 3.5 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Vma12 PF11712.3 ETO25291.1 - 3 7.5 5.6 0.97 9.1 0.7 2.3 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Endonuclease_5 PF04493.9 ETO25292.1 - 1.9e-47 161.3 0.1 8.1e-44 149.4 0.0 2.8 2 1 0 2 2 2 2 Endonuclease V UvrC_HhH_N PF08459.6 ETO25292.1 - 0.0018 17.8 0.0 0.013 15.0 0.0 2.4 1 1 0 1 1 1 1 UvrC Helix-hairpin-helix N-terminal Tho2 PF11262.3 ETO25293.1 - 5e-38 130.8 5.8 2.1e-33 115.6 1.4 3.9 3 1 1 4 4 4 2 Transcription factor/nuclear export subunit protein 2 Sec23_trunk PF04811.10 ETO25294.1 - 1.2e-09 37.8 0.1 6.9e-09 35.4 0.1 2.1 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain VWA_2 PF13519.1 ETO25294.1 - 1.1e-08 35.4 0.0 2.2e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-Sec23_Sec24 PF04810.10 ETO25295.1 - 0.00013 21.4 0.2 0.00042 19.8 0.2 1.9 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger PUB PF09409.5 ETO25297.1 - 0.022 14.4 0.5 0.07 12.8 0.3 1.8 1 0 0 1 1 1 0 PUB domain DUF294 PF03445.8 ETO25297.1 - 0.071 12.7 0.1 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Putative nucleotidyltransferase DUF294 AAA PF00004.24 ETO25298.1 - 5.6e-05 23.3 1.6 8.4e-05 22.7 0.1 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 ETO25298.1 - 0.0032 16.5 0.0 0.0077 15.2 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 ETO25298.1 - 0.01 15.8 0.0 0.01 15.8 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 ETO25298.1 - 0.02 14.6 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 ETO25298.1 - 0.021 14.9 0.0 0.049 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 ETO25298.1 - 0.077 13.8 0.0 0.077 13.8 0.0 3.1 3 1 0 3 3 3 0 AAA domain Med15 PF09606.5 ETO25298.1 - 3.6 5.6 41.4 4.8 5.2 28.7 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Cep57_CLD PF14073.1 ETO25299.1 - 0.058 13.2 0.1 0.058 13.2 0.1 1.9 3 0 0 3 3 3 0 Centrosome localisation domain of Cep57 CtIP_N PF10482.4 ETO25299.1 - 0.23 11.2 8.8 4.6 7.0 1.4 3.4 2 1 2 4 4 4 0 Tumour-suppressor protein CtIP N-terminal domain DUF962 PF06127.6 ETO25300.1 - 7.7e-23 80.2 3.3 2.7e-22 78.4 2.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF962) TcpE PF12648.2 ETO25300.1 - 0.6 10.2 0.1 0.6 10.2 0.0 3.5 1 1 2 3 3 3 0 TcpE family zf-DHHC PF01529.15 ETO25300.1 - 2.3 7.5 4.9 1.7 8.0 1.7 1.9 2 0 0 2 2 2 0 DHHC palmitoyltransferase SbcCD_C PF13558.1 ETO25301.1 - 2.7e-11 43.2 0.0 7.6e-11 41.7 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 ETO25301.1 - 7.1e-05 22.1 11.8 7.1e-05 22.1 8.2 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_13 PF13166.1 ETO25301.1 - 0.00014 20.5 65.3 0.00015 20.4 21.9 3.3 2 2 0 2 2 2 2 AAA domain AAA_21 PF13304.1 ETO25301.1 - 0.00024 21.1 1.6 0.001 19.1 0.7 2.3 1 1 0 1 1 1 1 AAA domain SH2 PF00017.19 ETO25301.1 - 0.061 13.1 0.5 0.44 10.3 0.3 2.5 1 0 0 1 1 1 0 SH2 domain Reo_sigmaC PF04582.7 ETO25301.1 - 1.4 8.0 21.7 0.15 11.2 3.9 3.6 3 2 1 4 4 4 0 Reovirus sigma C capsid protein PspB PF06667.7 ETO25301.1 - 2.3 8.2 8.7 0.92 9.4 0.0 4.2 3 1 1 4 4 4 0 Phage shock protein B AAA_23 PF13476.1 ETO25302.1 - 2.2e-23 83.6 0.1 2.2e-23 83.6 0.1 4.7 3 2 0 3 3 2 1 AAA domain SMC_N PF02463.14 ETO25302.1 - 8.1e-09 35.0 0.0 8.1e-09 35.0 0.0 3.0 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 ETO25302.1 - 1.6e-07 30.7 6.4 1.6e-07 30.7 4.4 3.9 1 1 1 2 2 1 1 AAA ATPase domain AAA_21 PF13304.1 ETO25302.1 - 9.5e-05 22.4 0.0 9.5e-05 22.4 0.0 4.1 2 1 1 4 4 4 1 AAA domain AAA_29 PF13555.1 ETO25302.1 - 0.00011 21.6 0.0 0.00026 20.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 ETO25302.1 - 0.0012 17.4 0.0 0.0012 17.4 0.0 4.7 2 2 1 4 4 2 1 AAA domain MobB PF03205.9 ETO25302.1 - 0.0059 16.3 0.2 0.12 12.0 0.0 3.1 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 ETO25302.1 - 0.012 15.0 2.3 0.31 10.4 0.0 3.2 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 ETO25302.1 - 0.013 15.7 0.0 0.013 15.7 0.0 4.3 2 1 0 2 2 1 0 ABC transporter DUF2674 PF10879.3 ETO25302.1 - 0.019 14.7 1.9 0.95 9.2 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2674) AAA_19 PF13245.1 ETO25302.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 ETO25302.1 - 0.21 12.3 6.3 0.55 11.0 0.0 3.9 3 1 0 3 3 3 0 AAA domain AAA_16 PF13191.1 ETO25302.1 - 0.29 11.1 0.0 0.29 11.1 0.0 3.0 3 2 1 4 4 4 0 AAA ATPase domain AAA_33 PF13671.1 ETO25302.1 - 0.32 10.8 0.0 0.32 10.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain IncA PF04156.9 ETO25302.1 - 0.9 9.0 51.4 0.36 10.3 6.1 5.7 4 2 1 5 5 5 0 IncA protein Prefoldin PF02996.12 ETO25303.1 - 8.9e-17 60.8 1.4 6.4e-16 58.0 0.1 2.2 2 0 0 2 2 2 1 Prefoldin subunit Orthopox_B11R PF07033.6 ETO25304.1 - 0.016 14.6 4.4 0.048 13.1 0.2 2.9 1 1 1 2 2 2 0 Orthopoxvirus B11R protein Tox-REase-2 PF15646.1 ETO25304.1 - 0.021 14.7 1.1 0.028 14.2 0.2 1.7 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 2 DUF445 PF04286.7 ETO25304.1 - 0.18 11.3 6.6 0.23 10.9 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) ATP-cone PF03477.11 ETO25304.1 - 0.77 10.2 4.0 8.4 6.9 0.0 2.6 3 0 0 3 3 3 0 ATP cone domain UvrD-helicase PF00580.16 ETO25304.1 - 1.4 8.1 7.6 2.2 7.5 5.3 1.3 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain Epsilon_antitox PF08998.6 ETO25304.1 - 2.8 7.9 6.5 0.9 9.5 0.8 2.6 2 2 0 2 2 2 0 Bacterial epsilon antitoxin SRP54_N PF02881.14 ETO25304.1 - 5.4 7.1 8.8 3.2 7.9 0.1 3.3 3 1 1 4 4 4 0 SRP54-type protein, helical bundle domain DUF106 PF01956.11 ETO25304.1 - 6.5 6.2 7.0 32 4.0 4.8 2.1 1 1 0 1 1 1 0 Integral membrane protein DUF106 DUF896 PF05979.7 ETO25304.1 - 7.7 6.1 8.8 1.3 8.6 0.7 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) DUF4509 PF14970.1 ETO25304.1 - 9.3 5.8 13.5 14 5.2 2.1 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4509) RGS PF00615.14 ETO25306.1 - 8.1e-07 29.1 0.5 1.5e-06 28.2 0.3 1.4 1 1 0 1 1 1 1 Regulator of G protein signaling domain PAH PF02671.16 ETO25307.1 - 0.00075 19.0 0.2 0.0019 17.8 0.2 1.7 1 0 0 1 1 1 1 Paired amphipathic helix repeat TFIIA PF03153.8 ETO25307.1 - 0.76 9.6 23.9 1.1 9.1 16.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 ETO25307.1 - 0.87 7.7 27.2 1.1 7.4 18.9 1.1 1 0 0 1 1 1 0 Transmembrane protein FSIP1 PF15554.1 ETO25307.1 - 1.2 7.8 17.8 2.3 6.9 12.3 1.4 1 0 0 1 1 1 0 FSIP1 family DUF3595 PF12166.3 ETO25308.1 - 0.3 9.8 3.5 0.6 8.8 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) Menin PF05053.8 ETO25308.1 - 3 5.9 6.8 3.9 5.5 4.7 1.2 1 0 0 1 1 1 0 Menin Tetraspannin PF00335.15 ETO25308.1 - 3.2 6.9 8.3 5.2 6.2 5.7 1.3 1 0 0 1 1 1 0 Tetraspanin family CAP PF00188.21 ETO25309.1 - 3.8e-05 24.1 0.1 3.8e-05 24.1 0.1 1.7 2 1 0 2 2 2 1 Cysteine-rich secretory protein family Phage_GPD PF05954.6 ETO25309.1 - 0.046 12.8 0.0 0.049 12.8 0.0 1.2 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) DEAD PF00270.24 ETO25309.1 - 0.11 11.9 0.1 0.38 10.2 0.0 1.7 1 1 0 2 2 2 0 DEAD/DEAH box helicase Sec3_C PF09763.4 ETO25310.1 - 5.4e-05 21.5 1.5 0.00024 19.4 0.4 1.9 2 0 0 2 2 2 1 Exocyst complex component Sec3 2-Hacid_dh_C PF02826.14 ETO25310.1 - 0.012 14.8 0.0 0.02 14.0 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3785 PF12653.2 ETO25312.1 - 0.041 13.7 0.2 0.078 12.8 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3785) V-ATPase_H_C PF11698.3 ETO25313.1 - 1.6e-36 124.8 1.0 3.9e-36 123.5 0.2 2.0 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_N PF03224.9 ETO25313.1 - 1.3e-09 37.6 0.9 1.3e-09 37.6 0.6 2.2 3 1 0 3 3 3 1 V-ATPase subunit H Arm PF00514.18 ETO25313.1 - 0.00011 21.8 0.1 0.83 9.5 0.0 3.0 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 ETO25313.1 - 0.00031 20.9 0.0 0.00076 19.7 0.0 1.7 1 0 0 1 1 1 1 HEAT repeats PhyH PF05721.8 ETO25314.1 - 1.1e-33 117.0 0.0 4.3e-33 115.1 0.0 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 ETO25314.1 - 0.032 12.7 0.0 0.92 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) Abhydrolase_5 PF12695.2 ETO25315.1 - 8.5e-05 22.3 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 ETO25315.1 - 0.024 14.5 0.0 0.056 13.3 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein Malic_M PF03949.10 ETO25315.1 - 0.052 13.0 0.1 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain EMP70 PF02990.11 ETO25316.1 - 1.2e-26 93.3 0.2 1.5e-26 92.9 0.1 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 FLYWCH PF04500.11 ETO25317.1 - 0.016 15.0 6.4 0.061 13.2 3.0 2.7 1 1 1 2 2 2 0 FLYWCH zinc finger domain FimP PF09766.4 ETO25319.1 - 0.0089 15.1 3.4 0.011 14.8 2.4 1.3 1 0 0 1 1 1 1 Fms-interacting protein DUF4548 PF15081.1 ETO25319.1 - 0.02 14.4 0.2 0.31 10.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4548) FCP1_C PF09309.5 ETO25319.1 - 0.92 8.7 7.5 0.3 10.3 3.2 1.6 2 0 0 2 2 2 0 FCP1, C-terminal Adaptin_N PF01602.15 ETO25320.1 - 1.5e-79 267.6 16.7 1.8e-79 267.4 11.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 ETO25320.1 - 3.9e-15 55.8 6.7 7.4e-07 29.3 0.0 4.7 2 1 2 4 4 4 4 HEAT repeats HEAT PF02985.17 ETO25320.1 - 1.7e-07 30.6 0.8 0.0072 16.3 0.0 4.4 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 ETO25320.1 - 1.7e-05 25.1 2.8 0.03 14.8 0.0 5.0 5 1 1 6 6 6 1 HEAT-like repeat Cnd1 PF12717.2 ETO25320.1 - 0.00083 19.2 8.3 0.021 14.6 0.1 4.3 2 2 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 DUF4456 PF14644.1 ETO25320.1 - 0.0047 16.1 0.1 0.067 12.4 0.0 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4456) Arm PF00514.18 ETO25320.1 - 2 8.3 8.5 54 3.8 0.0 5.1 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Serum_albumin PF00273.15 ETO25321.1 - 0.011 15.2 0.7 0.018 14.4 0.5 1.3 1 0 0 1 1 1 0 Serum albumin family WD40 PF00400.27 ETO25322.1 - 3e-63 207.6 9.5 8.3e-11 41.3 0.0 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO25322.1 - 1.1e-08 34.8 3.6 0.0022 18.0 0.0 5.7 6 0 0 6 6 5 2 Kelch motif Kelch_1 PF01344.20 ETO25322.1 - 9.8e-08 31.4 4.3 4.1e-05 23.0 0.0 4.3 5 0 0 5 5 5 2 Kelch motif Nup160 PF11715.3 ETO25322.1 - 2e-07 29.5 0.9 0.37 8.8 0.0 4.5 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Kelch_5 PF13854.1 ETO25322.1 - 1.7e-05 24.6 2.6 0.049 13.6 0.1 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO25322.1 - 0.0013 18.8 0.0 0.0073 16.4 0.0 2.4 2 0 0 2 2 2 1 Galactose oxidase, central domain Cytochrom_D1 PF02239.11 ETO25322.1 - 0.0017 16.7 1.4 0.4 8.9 0.1 3.2 1 1 2 3 3 3 1 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO25322.1 - 0.0021 17.2 0.2 6.1 5.8 0.0 3.5 1 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal DUF2120 PF09893.4 ETO25322.1 - 0.003 17.4 0.9 0.052 13.4 0.9 2.5 3 0 0 3 3 3 1 Uncharacterized protein conserved in archaea (DUF2120) DUF4355 PF14265.1 ETO25322.1 - 0.067 13.1 7.8 0.11 12.4 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Proteasome_A_N PF10584.4 ETO25322.1 - 0.25 10.6 1.1 26 4.2 0.0 3.8 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Aldo_ket_red PF00248.16 ETO25323.1 - 4.1e-24 84.8 0.1 3.9e-18 65.2 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family DSPc PF00782.15 ETO25324.1 - 5.8e-28 97.1 0.3 9.4e-17 60.8 0.0 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 ETO25324.1 - 2.6e-05 24.3 0.0 6.9e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 ETO25324.1 - 0.0012 18.2 0.4 0.0021 17.4 0.3 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Phenyl_P_gamma PF09662.5 ETO25325.1 - 0.082 12.6 0.9 1.1 9.0 0.0 2.4 1 1 1 2 2 2 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) DUF2365 PF10157.4 ETO25325.1 - 0.096 12.5 1.5 0.75 9.6 0.1 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2365) Snapin_Pallidin PF14712.1 ETO25325.1 - 6.8 7.0 7.2 5 7.4 0.3 2.4 2 1 1 3 3 3 0 Snapin/Pallidin DASH_Spc34 PF08657.5 ETO25326.1 - 0.019 14.6 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 DASH complex subunit Spc34 ETC_C1_NDUFA5 PF04716.9 ETO25328.1 - 1.8e-14 52.9 0.2 4.1e-14 51.8 0.2 1.6 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF663 PF04950.7 ETO25329.1 - 6.2e-73 245.3 0.0 6.2e-73 245.3 0.0 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 ETO25330.1 - 7.4e-29 99.1 0.1 3.5e-28 96.9 0.0 2.2 2 0 0 2 2 2 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 ETO25330.1 - 5.3e-06 25.9 0.0 5.7e-05 22.6 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 ETO25330.1 - 0.00046 20.1 0.0 0.0023 17.8 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 ETO25330.1 - 0.0033 17.5 0.1 0.02 15.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 ETO25330.1 - 0.0036 17.4 3.4 2.2 8.4 0.0 3.7 3 0 0 3 3 3 1 RNA helicase AAA_25 PF13481.1 ETO25330.1 - 0.015 14.7 0.0 0.05 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETO25330.1 - 0.025 14.5 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.9 ETO25330.1 - 0.032 13.9 0.1 0.086 12.5 0.0 1.8 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 ETO25330.1 - 0.052 14.0 0.0 0.22 12.0 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein AAA PF00004.24 ETO25330.1 - 0.076 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Herpes_LP PF03363.8 ETO25330.1 - 0.12 11.9 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus leader protein AAA_17 PF13207.1 ETO25330.1 - 0.5 11.1 0.0 0.5 11.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 ETO25330.1 - 1.6 8.4 7.5 53 3.5 0.0 4.5 2 2 0 4 4 4 0 Dynamin family KH_1 PF00013.24 ETO25331.1 - 3.7e-11 42.4 0.1 6.3e-06 25.7 0.1 3.4 2 1 0 2 2 2 2 KH domain KH_3 PF13014.1 ETO25331.1 - 0.0032 17.0 0.6 0.01 15.4 0.3 1.9 2 0 0 2 2 2 1 KH domain Collagen PF01391.13 ETO25331.1 - 0.0098 15.4 17.4 0.017 14.6 12.1 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF781 PF05612.7 ETO25331.1 - 0.12 11.0 0.1 0.21 10.2 0.1 1.3 1 0 0 1 1 1 0 Mouse protein of unknown function (DUF781) Adeno_E3_15_3 PF03307.9 ETO25331.1 - 0.87 9.3 4.5 16 5.2 0.1 2.8 3 0 0 3 3 3 0 Adenovirus 15.3kD protein in E3 region IF-2 PF11987.3 ETO25332.1 - 3.4e-16 59.0 0.0 5.9e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU PF00009.22 ETO25333.1 - 1e-25 90.3 6.0 1.1e-20 73.8 0.2 3.6 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 ETO25333.1 - 6.2e-05 22.9 0.0 0.00016 21.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 ETO25333.1 - 0.00053 20.4 0.0 0.0024 18.3 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 ETO25333.1 - 0.003 16.8 0.0 0.75 8.9 0.0 2.5 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 ETO25333.1 - 0.068 12.7 0.0 2.8 7.3 0.0 2.6 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein DEAD PF00270.24 ETO25334.1 - 1.1e-40 138.8 0.1 2.4e-40 137.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETO25334.1 - 3.9e-24 84.3 0.1 1.1e-23 82.8 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Zip PF02535.17 ETO25334.1 - 0.00067 18.7 1.0 0.1 11.6 0.1 2.3 2 0 0 2 2 2 2 ZIP Zinc transporter WD40 PF00400.27 ETO25336.1 - 7.8e-10 38.2 0.0 1.8e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO25336.1 - 0.017 13.2 0.0 0.021 12.9 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 PB1 PF00564.19 ETO25337.1 - 2.3e-13 49.6 0.6 2.8e-13 49.3 0.4 1.1 1 0 0 1 1 1 1 PB1 domain RNA_pol_Rpb1_7 PF04990.7 ETO25337.1 - 0.27 10.9 3.1 0.22 11.2 1.1 1.6 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 7 DUF3169 PF11368.3 ETO25338.1 - 0.12 11.5 5.2 0.045 12.9 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) BPL_N PF09825.4 ETO25339.1 - 3.4 6.3 8.2 5.1 5.7 5.7 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Ndc1_Nup PF09531.5 ETO25339.1 - 7.3 4.8 11.4 8.6 4.6 7.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3791 PF12668.2 ETO25340.1 - 0.016 14.8 0.7 1.4 8.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) BCD PF15461.1 ETO25340.1 - 0.038 13.3 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 Beta-carotene 15,15'-dioxygenase DEAD PF00270.24 ETO25341.1 - 1.8e-45 154.4 0.0 3.3e-44 150.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETO25341.1 - 4.2e-27 93.8 0.1 9.4e-27 92.6 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 ETO25341.1 - 0.0018 16.7 0.0 1.3 7.3 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF1253) ResIII PF04851.10 ETO25341.1 - 0.01 15.6 0.0 0.11 12.3 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Scs3p PF10261.4 ETO25342.1 - 3.9e-06 26.0 3.4 3.9e-06 26.0 2.4 2.0 2 0 0 2 2 2 1 Inositol phospholipid synthesis and fat-storage-inducing TM DUF1673 PF07895.6 ETO25342.1 - 0.00041 19.9 7.6 0.00055 19.5 5.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1673) fn3 PF00041.16 ETO25343.1 - 4.6e-05 23.4 0.0 0.00017 21.6 0.0 2.0 1 0 0 1 1 1 1 Fibronectin type III domain LMBR1 PF04791.11 ETO25343.1 - 0.056 12.0 0.0 0.056 12.0 0.0 2.0 2 0 0 2 2 2 0 LMBR1-like membrane protein Apis_Csd PF11671.3 ETO25344.1 - 2 8.1 8.3 0.16 11.7 2.2 1.8 2 0 0 2 2 2 0 Complementary sex determiner protein DcuC PF03606.10 ETO25345.1 - 1.7 6.7 11.1 0.015 13.6 1.0 2.1 2 1 0 2 2 2 0 C4-dicarboxylate anaerobic carrier Alg6_Alg8 PF03155.10 ETO25346.1 - 9.7e-52 176.3 3.2 1.2e-51 175.9 2.2 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Ribonuclease_T2 PF00445.13 ETO25347.1 - 1.9e-17 63.5 0.7 2.2e-17 63.2 0.5 1.0 1 0 0 1 1 1 1 Ribonuclease T2 family Glyco_hydro_63 PF03200.11 ETO25348.1 - 1.6e-40 138.7 0.1 1.7e-40 138.6 0.1 1.1 1 0 0 1 1 1 1 Mannosyl oligosaccharide glucosidase DUF3606 PF12244.3 ETO25348.1 - 0.0097 15.5 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3606) Glyco_hydro_63 PF03200.11 ETO25349.1 - 2.5e-15 55.4 0.1 2.7e-15 55.3 0.0 1.3 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase MCD PF05292.6 ETO25349.1 - 0.011 14.4 0.0 0.015 14.0 0.0 1.1 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase (MCD) Glyco_hydro_63 PF03200.11 ETO25350.1 - 1.3e-13 49.7 1.0 1.3e-13 49.7 0.7 1.1 1 0 0 1 1 1 1 Mannosyl oligosaccharide glucosidase OPA3 PF07047.7 ETO25351.1 - 0.00014 21.6 0.0 0.0002 21.1 0.0 1.3 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Hyccin PF09790.4 ETO25353.1 - 4.7e-09 35.5 7.6 3.6e-05 22.7 0.1 3.2 3 0 0 3 3 3 2 Hyccin DUF3015 PF11220.3 ETO25353.1 - 1.3 8.5 10.0 0.052 13.1 2.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3015) TMEM154 PF15102.1 ETO25353.1 - 8.4 6.0 14.8 19 4.9 3.8 3.3 3 0 0 3 3 3 0 TMEM154 protein family Myb_DNA-binding PF00249.26 ETO25354.1 - 0.00073 19.5 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2304 PF10066.4 ETO25355.1 - 8.1 6.3 8.7 7.9 6.3 1.1 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) zf-RING_2 PF13639.1 ETO25356.1 - 5.3e-08 32.5 8.5 5.3e-08 32.5 5.9 2.8 2 0 0 2 2 2 1 Ring finger domain RINGv PF12906.2 ETO25356.1 - 9.4e-05 22.3 7.2 0.00045 20.2 5.0 2.3 1 0 0 1 1 1 1 RING-variant domain GAGA PF09237.6 ETO25356.1 - 0.096 12.2 4.0 0.45 10.1 0.1 2.9 3 0 0 3 3 3 0 GAGA factor DUF4407 PF14362.1 ETO25356.1 - 0.25 10.2 1.4 0.5 9.2 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ctr PF04145.10 ETO25356.1 - 0.3 11.1 6.7 24 4.9 0.0 3.7 2 1 0 2 2 2 0 Ctr copper transporter family Mannosyl_trans3 PF11051.3 ETO25357.1 - 5.8e-05 22.5 0.0 7.7e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative Cons_hypoth95 PF03602.10 ETO25357.1 - 0.13 11.6 0.1 0.37 10.1 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical protein 95 DIT1_PvcA PF05141.7 ETO25358.1 - 0.0045 16.3 9.3 0.0061 15.9 6.5 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein DUF3552 PF12072.3 ETO25358.1 - 3.1 6.9 25.8 5.7 6.0 17.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Mo25 PF08569.6 ETO25359.1 - 4.9e-08 32.3 16.0 1.9e-07 30.4 11.1 1.8 1 1 0 1 1 1 1 Mo25-like FAM176 PF14851.1 ETO25359.1 - 2.4 7.8 9.0 6.8 6.3 6.3 1.6 1 1 0 1 1 1 0 FAM176 family RNA_pol_Rpb1_5 PF04998.12 ETO25359.1 - 4.6 6.4 9.7 5.4 6.1 6.7 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF4604 PF15377.1 ETO25359.1 - 6.9 6.8 25.2 11 6.1 17.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) CopD PF05425.8 ETO25360.1 - 0.61 10.3 5.7 0.12 12.5 1.3 1.9 2 0 0 2 2 2 0 Copper resistance protein D OAD_gamma PF04277.8 ETO25362.1 - 0.35 11.2 2.2 5.1 7.5 0.1 3.0 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain RGS PF00615.14 ETO25363.1 - 2.1e-06 27.8 0.1 2.1e-06 27.8 0.1 2.0 2 0 0 2 2 2 1 Regulator of G protein signaling domain DUF4436 PF14494.1 ETO25363.1 - 0.0072 15.6 2.6 0.0072 15.6 1.8 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4436) DUF4131 PF13567.1 ETO25363.1 - 0.055 12.8 3.5 0.066 12.6 1.3 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4557 PF15101.1 ETO25363.1 - 1.4 8.6 8.0 0.12 12.2 2.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Adaptin_N PF01602.15 ETO25364.1 - 0.027 12.8 0.0 0.029 12.6 0.0 1.1 1 0 0 1 1 1 0 Adaptin N terminal region PB1 PF00564.19 ETO25365.1 - 2.8e-14 52.5 0.1 3.5e-14 52.2 0.1 1.1 1 0 0 1 1 1 1 PB1 domain Abi_2 PF07751.6 ETO25365.1 - 0.082 13.0 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Abi-like protein GPS PF01825.16 ETO25366.1 - 8.7e-10 38.5 3.5 2.8e-09 36.9 2.4 1.9 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain REJ PF02010.10 ETO25366.1 - 3.3e-09 35.5 4.5 3.3e-09 35.5 3.1 2.2 2 0 0 2 2 2 1 REJ domain PT PF04886.7 ETO25368.1 - 0.0024 17.1 32.3 0.0039 16.4 14.0 2.6 1 1 1 2 2 2 2 PT repeat RRM_1 PF00076.17 ETO25370.1 - 2.9e-08 33.2 0.0 5.5e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO25370.1 - 7.6e-06 25.8 0.0 0.00059 19.7 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO25370.1 - 5.4e-05 22.9 0.4 0.0058 16.4 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med15 PF09606.5 ETO25370.1 - 4.4 5.3 55.0 5.1 5.1 38.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF605 PF04652.11 ETO25370.1 - 6.2 6.1 28.4 8.1 5.7 19.7 1.1 1 0 0 1 1 1 0 Vta1 like FtsH_ext PF06480.10 ETO25371.1 - 0.13 12.4 1.2 0.3 11.2 0.9 1.6 1 1 0 1 1 1 0 FtsH Extracellular Protocadherin PF08374.6 ETO25371.1 - 5.8 6.4 11.8 8 6.0 0.9 2.3 1 1 1 2 2 2 0 Protocadherin Mic1 PF07035.7 ETO25372.1 - 0.048 13.0 0.1 0.14 11.5 0.1 1.7 1 1 1 2 2 2 0 Colon cancer-associated protein Mic1-like Hydrolase_3 PF08282.7 ETO25373.1 - 3.6 7.0 8.6 1.9 7.9 4.5 1.5 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Metallophos_2 PF12850.2 ETO25374.1 - 0.00027 20.8 0.0 0.00095 19.0 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Miro PF08477.8 ETO25374.1 - 0.00038 20.9 0.4 0.00073 20.0 0.3 1.5 1 0 0 1 1 1 1 Miro-like protein Metallophos PF00149.23 ETO25374.1 - 0.0016 17.9 1.5 0.003 16.9 0.5 1.9 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase EF-hand_6 PF13405.1 ETO25376.1 - 0.00015 21.3 0.3 0.0077 16.0 0.0 3.2 2 1 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 ETO25376.1 - 0.011 15.9 2.6 1.2 9.3 0.0 2.8 2 2 0 2 2 2 0 EF-hand domain pair DUF4550 PF15084.1 ETO25376.1 - 0.073 13.1 1.1 0.16 12.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4550) HHA PF05321.6 ETO25376.1 - 0.11 12.5 0.2 0.59 10.3 0.0 2.3 3 0 0 3 3 3 0 Haemolysin expression modulating protein RRM_1 PF00076.17 ETO25378.1 - 3.1e-09 36.3 0.0 4.4e-06 26.2 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO25378.1 - 3.2e-09 36.6 0.0 3e-08 33.5 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO25378.1 - 4.9e-07 29.4 0.0 0.00011 22.0 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BAF1_ABF1 PF04684.8 ETO25378.1 - 0.0068 15.3 11.7 0.0088 14.9 8.1 1.1 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor RRM_3 PF08777.6 ETO25378.1 - 0.021 14.6 0.1 1.1 9.1 0.0 2.5 2 1 0 2 2 2 0 RNA binding motif Zip PF02535.17 ETO25378.1 - 0.05 12.6 8.1 0.057 12.4 5.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 ETO25378.1 - 0.056 12.8 19.7 0.033 13.5 12.1 1.7 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Menin PF05053.8 ETO25378.1 - 0.06 11.5 4.7 0.07 11.2 3.3 1.1 1 0 0 1 1 1 0 Menin RP-C_C PF11800.3 ETO25378.1 - 0.13 11.9 7.0 0.2 11.3 4.8 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Macoilin PF09726.4 ETO25378.1 - 0.81 7.8 16.0 1.1 7.4 11.1 1.1 1 0 0 1 1 1 0 Transmembrane protein NicO PF03824.11 ETO25378.1 - 3.2 6.9 6.2 4.7 6.4 4.3 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein Otopetrin PF03189.8 ETO25378.1 - 3.7 6.4 6.2 5.1 5.9 4.3 1.2 1 0 0 1 1 1 0 Otopetrin RIC3 PF15361.1 ETO25378.1 - 4.3 7.5 6.3 8.5 6.6 4.4 1.4 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 RRM_1 PF00076.17 ETO25379.1 - 1.5e-31 107.8 0.0 6.4e-18 64.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO25379.1 - 4.7e-20 71.1 0.1 8e-11 41.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO25379.1 - 5e-20 71.2 0.0 5.7e-11 42.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 ETO25379.1 - 1.3e-05 24.9 0.0 0.0034 17.1 0.0 2.2 1 1 1 2 2 2 2 RNA binding motif RNA_bind PF08675.6 ETO25379.1 - 0.00011 22.1 0.0 0.0011 18.9 0.0 2.3 2 0 0 2 2 2 1 RNA binding domain DUF4283 PF14111.1 ETO25379.1 - 0.015 14.4 0.1 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4283) Limkain-b1 PF11608.3 ETO25379.1 - 0.02 14.6 0.0 0.08 12.7 0.0 1.8 2 0 0 2 2 2 0 Limkain b1 Nup35_RRM_2 PF14605.1 ETO25379.1 - 0.046 13.4 0.0 6.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif ParD PF09386.5 ETO25379.1 - 0.11 12.6 0.0 0.91 9.6 0.0 2.2 1 1 1 2 2 2 0 Antitoxin ParD TPR_17 PF13431.1 ETO25380.1 - 0.0015 18.5 0.2 3.5 8.0 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO25380.1 - 0.017 14.7 0.2 0.71 9.5 0.0 2.4 2 0 0 2 2 2 0 TPR repeat RXT2_N PF08595.6 ETO25381.1 - 1.6 8.5 13.0 1.1 8.9 1.3 2.8 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF4252 PF14060.1 ETO25382.1 - 0.0037 16.8 0.0 0.007 15.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4252) PLDc PF00614.17 ETO25382.1 - 0.033 13.9 0.0 0.16 11.8 0.0 2.2 2 1 0 2 2 2 0 Phospholipase D Active site motif Acetyltransf_1 PF00583.19 ETO25383.1 - 2e-08 34.1 0.0 3.2e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETO25383.1 - 5.9e-08 32.7 0.0 1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETO25383.1 - 6.7e-05 22.9 0.0 9.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 ETO25383.1 - 0.043 13.7 0.0 0.062 13.1 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain SSP160 PF06933.6 ETO25384.1 - 0.033 12.1 18.6 0.035 12.1 6.4 2.2 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 FAD_binding_2 PF00890.19 ETO25385.1 - 3e-42 144.9 0.0 4.9e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETO25385.1 - 1.6e-06 27.3 0.0 3.6e-06 26.1 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETO25385.1 - 5.1e-05 23.2 0.6 0.00014 21.8 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETO25385.1 - 9.1e-05 22.4 0.3 0.0036 17.2 0.2 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF4287 PF14117.1 ETO25385.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4287) FAD_binding_2 PF00890.19 ETO25386.1 - 4.3e-24 85.1 0.0 5e-24 84.9 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain SAPS PF04499.10 ETO25387.1 - 4.6e-45 154.1 20.0 9.1e-25 87.2 1.9 4.1 3 1 1 4 4 4 4 SIT4 phosphatase-associated protein DUF1804 PF08822.6 ETO25387.1 - 0.11 12.2 0.1 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) SMN PF06003.7 ETO25387.1 - 1.2 8.2 4.9 1.9 7.4 3.4 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) BUD22 PF09073.5 ETO25387.1 - 6.3 5.7 10.0 10 5.0 6.9 1.2 1 0 0 1 1 1 0 BUD22 DUF572 PF04502.8 ETO25388.1 - 0.029 13.5 13.2 0.037 13.2 9.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) SRP-alpha_N PF04086.8 ETO25388.1 - 0.096 12.0 14.0 0.12 11.6 9.7 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal FEZ PF07763.8 ETO25388.1 - 0.24 11.0 16.4 0.94 9.1 11.4 1.8 1 1 0 1 1 1 0 FEZ-like protein Mit_KHE1 PF10173.4 ETO25388.1 - 0.31 10.8 4.4 0.45 10.3 3.1 1.3 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related AIF_C PF14721.1 ETO25388.1 - 2 8.6 9.4 0.11 12.7 0.7 2.2 1 1 1 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Apt1 PF10351.4 ETO25388.1 - 2.9 6.6 14.4 4.8 5.9 10.0 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.9 ETO25388.1 - 9.3 4.1 12.8 12 3.7 8.9 1.1 1 0 0 1 1 1 0 CDC45-like protein TPR_8 PF13181.1 ETO25389.1 - 7.5e-06 25.3 2.2 0.0018 17.9 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO25389.1 - 6.8e-05 23.4 0.0 0.00022 21.8 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF2264 PF10022.4 ETO25389.1 - 7.4e-05 21.5 0.2 0.00015 20.5 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) TPR_2 PF07719.12 ETO25389.1 - 0.00038 20.1 3.8 0.013 15.3 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO25389.1 - 0.00082 18.8 4.3 0.064 12.8 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO25389.1 - 0.0025 17.3 0.7 0.27 10.9 0.0 3.3 3 0 0 3 3 3 1 TPR repeat TPR_9 PF13371.1 ETO25389.1 - 0.072 12.9 0.0 0.59 10.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO25389.1 - 0.088 13.3 0.2 5.4 7.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2201_N PF13203.1 ETO25389.1 - 0.14 11.2 2.7 0.93 8.5 1.2 2.3 2 0 0 2 2 2 0 Putative metallopeptidase domain DUF3671 PF12420.3 ETO25390.1 - 0.00062 19.6 2.2 0.00062 19.6 1.5 2.1 2 0 0 2 2 2 1 Protein of unknown function DUF4199 PF13858.1 ETO25390.1 - 0.0014 18.5 3.9 0.0032 17.4 0.1 2.7 3 1 0 3 3 3 1 Protein of unknown function (DUF4199) NicO PF03824.11 ETO25390.1 - 0.008 15.5 0.4 0.008 15.5 0.3 2.0 2 0 0 2 2 2 1 High-affinity nickel-transport protein DUF2207 PF09972.4 ETO25390.1 - 0.018 13.6 3.2 0.9 8.0 0.3 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) 2HCT PF03390.10 ETO25390.1 - 0.032 12.6 1.8 0.034 12.5 0.6 1.5 2 0 0 2 2 2 0 2-hydroxycarboxylate transporter family Ni_hydr_CYTB PF01292.15 ETO25390.1 - 0.038 13.3 0.4 2.9 7.2 0.0 2.2 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 Cytochrom_B_N PF00033.14 ETO25390.1 - 0.061 12.6 3.4 0.91 8.8 2.7 2.2 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB 60KD_IMP PF02096.15 ETO25390.1 - 0.41 10.2 4.6 19 4.8 0.0 2.8 1 1 0 2 2 2 0 60Kd inner membrane protein WBP-1 PF11669.3 ETO25390.1 - 2.1 8.4 11.8 5.2 7.1 0.4 3.3 2 1 1 3 3 3 0 WW domain-binding protein 1 FtsX PF02687.16 ETO25390.1 - 6.3 6.5 14.3 1.1 9.0 0.8 2.4 1 1 2 3 3 3 0 FtsX-like permease family DUF3228 PF11539.3 ETO25391.1 - 0.03 13.4 1.8 0.056 12.5 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3228) Cupin_8 PF13621.1 ETO25392.1 - 0.059 12.8 4.0 0.12 11.8 0.3 2.8 2 1 0 2 2 2 0 Cupin-like domain Ank PF00023.25 ETO25392.1 - 0.16 11.8 0.2 0.49 10.3 0.1 1.9 1 0 0 1 1 1 0 Ankyrin repeat TRADD_N PF09034.5 ETO25393.1 - 0.068 13.1 1.2 0.16 11.9 0.1 2.1 2 0 0 2 2 2 0 TRADD, N-terminal domain RRM_6 PF14259.1 ETO25394.1 - 1.5e-08 34.4 0.0 0.00072 19.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO25394.1 - 2.5e-06 27.0 0.0 0.0065 16.0 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO25394.1 - 0.0086 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAF1C_H4-bd PF12265.3 ETO25395.1 - 1.1e-06 28.4 1.3 1.1e-06 28.4 0.9 2.3 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 ETO25396.1 - 7.3e-16 57.3 4.3 0.00028 20.6 0.0 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 ETO25396.1 - 0.0044 16.4 3.3 0.14 11.6 0.0 4.2 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain FAA_hydrolase PF01557.13 ETO25397.1 - 3.9e-64 216.0 0.0 4.5e-64 215.8 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Peptidase_M23 PF01551.17 ETO25399.1 - 1.9e-05 24.6 0.0 3.8e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M23 Prog_receptor PF02161.10 ETO25399.1 - 0.011 14.5 0.0 0.013 14.3 0.0 1.0 1 0 0 1 1 1 0 Progesterone receptor Menin PF05053.8 ETO25399.1 - 0.012 13.7 0.7 0.012 13.8 0.5 1.1 1 0 0 1 1 1 0 Menin Apis_Csd PF11671.3 ETO25399.1 - 0.042 13.6 8.5 0.06 13.1 5.9 1.4 1 0 0 1 1 1 0 Complementary sex determiner protein RnfC_N PF13375.1 ETO25399.1 - 0.08 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Tfb4 PF03850.9 ETO25399.1 - 0.88 8.7 5.8 1.3 8.1 4.0 1.2 1 0 0 1 1 1 0 Transcription factor Tfb4 APC_CDC26 PF10471.4 ETO25399.1 - 2.8 8.7 10.3 4.6 8.0 7.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Secretin_N_2 PF07655.8 ETO25399.1 - 3.7 8.0 17.9 5.8 7.3 12.4 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain Methyltransf_12 PF08242.7 ETO25399.1 - 6.1 7.3 6.2 45 4.5 4.3 2.1 1 1 0 1 1 1 0 Methyltransferase domain RRM_1 PF00076.17 ETO25400.1 - 0.012 15.2 0.0 0.049 13.2 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF936 PF06075.7 ETO25400.1 - 0.51 9.1 8.6 0.61 8.9 6.0 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) NST1 PF13945.1 ETO25400.1 - 0.53 10.3 16.2 2.1 8.3 2.6 2.3 2 0 0 2 2 2 0 Salt tolerance down-regulator SURF6 PF04935.7 ETO25400.1 - 0.75 9.0 29.2 0.038 13.2 8.4 2.5 1 1 1 2 2 2 0 Surfeit locus protein 6 FAM176 PF14851.1 ETO25400.1 - 1.8 8.2 5.6 0.15 11.7 0.2 1.9 2 0 0 2 2 2 0 FAM176 family AFT PF08731.6 ETO25400.1 - 1.9 8.7 9.8 1.2 9.3 1.5 3.0 3 0 0 3 3 3 0 Transcription factor AFT Peptidase_S49_N PF08496.5 ETO25400.1 - 3.5 7.3 12.5 6.4 6.5 0.4 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Macoilin PF09726.4 ETO25401.1 - 0.0045 15.3 15.1 0.005 15.1 10.5 1.1 1 0 0 1 1 1 1 Transmembrane protein DUF1569 PF07606.6 ETO25401.1 - 0.25 11.2 2.8 11 5.9 0.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1569) bZIP_1 PF00170.16 ETO25401.1 - 0.43 10.5 9.2 0.15 12.0 0.5 3.4 3 0 0 3 3 3 0 bZIP transcription factor MADF_DNA_bdg PF10545.4 ETO25401.1 - 0.46 10.7 5.6 0.13 12.4 0.4 2.4 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like FadA PF09403.5 ETO25401.1 - 0.66 10.0 7.0 0.48 10.4 0.2 2.5 2 1 1 3 3 3 0 Adhesion protein FadA GrpE PF01025.14 ETO25401.1 - 0.79 9.2 7.7 2.4 7.7 0.4 2.2 2 0 0 2 2 2 0 GrpE Plasmodium_Vir PF05795.6 ETO25401.1 - 1.5 7.9 13.8 3 6.9 9.6 1.3 1 1 0 1 1 1 0 Plasmodium vivax Vir protein APG6 PF04111.7 ETO25401.1 - 1.7 7.6 20.1 1.7 7.6 4.1 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Fib_alpha PF08702.5 ETO25401.1 - 2.1 8.4 18.7 2 8.5 1.2 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Pox_H7 PF04787.7 ETO25401.1 - 2.6 7.8 7.4 0.36 10.6 1.9 1.8 2 0 0 2 2 2 0 Late protein H7 Prp19 PF08606.6 ETO25401.1 - 2.7 7.8 7.1 1.7 8.4 0.1 2.7 2 1 1 3 3 3 0 Prp19/Pso4-like DUF904 PF06005.7 ETO25401.1 - 3.1 8.1 19.5 3 8.2 2.4 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF904) ATG16 PF08614.6 ETO25401.1 - 3.4 7.4 23.4 67 3.2 15.6 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF677 PF05055.7 ETO25402.1 - 0.00095 17.9 3.0 0.0079 14.9 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF677) Myosin_tail_1 PF01576.14 ETO25402.1 - 0.0014 16.4 17.3 0.0021 15.8 4.0 2.2 2 0 0 2 2 2 2 Myosin tail Laminin_I PF06008.9 ETO25402.1 - 0.0024 17.2 5.1 0.0024 17.2 3.5 2.5 3 0 0 3 3 3 1 Laminin Domain I Reo_sigmaC PF04582.7 ETO25402.1 - 0.004 16.3 3.1 0.031 13.4 0.1 2.1 2 0 0 2 2 2 1 Reovirus sigma C capsid protein ATG16 PF08614.6 ETO25402.1 - 0.058 13.2 18.3 0.046 13.5 3.5 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF4140 PF13600.1 ETO25402.1 - 0.064 13.7 18.6 0.43 11.0 2.3 2.9 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Uds1 PF15456.1 ETO25402.1 - 0.066 13.2 19.0 0.14 12.1 2.9 3.3 2 1 1 3 3 3 0 Up-regulated During Septation LXG PF04740.7 ETO25402.1 - 0.087 12.6 12.8 0.26 11.0 2.0 2.4 2 0 0 2 2 2 0 LXG domain of WXG superfamily IncA PF04156.9 ETO25402.1 - 0.11 12.0 23.2 0.67 9.5 2.5 2.3 2 1 0 2 2 2 0 IncA protein Spc7 PF08317.6 ETO25402.1 - 0.15 10.6 17.1 0.22 10.1 3.8 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.6 ETO25402.1 - 0.38 11.1 10.1 1.6 9.1 1.3 2.5 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Laminin_II PF06009.7 ETO25402.1 - 0.39 10.4 14.6 0.4 10.4 2.8 2.2 2 0 0 2 2 2 0 Laminin Domain II DUF948 PF06103.6 ETO25402.1 - 0.43 10.4 8.7 2.7 7.9 0.6 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) GAS PF13851.1 ETO25402.1 - 0.59 9.2 26.0 0.068 12.3 4.2 2.6 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 ETO25402.1 - 1 9.1 26.1 0.42 10.4 3.6 3.2 3 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.7 ETO25402.1 - 1.3 8.8 7.8 7.9 6.3 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ADIP PF11559.3 ETO25402.1 - 1.4 8.8 24.9 0.98 9.3 6.7 2.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding BLOC1_2 PF10046.4 ETO25402.1 - 1.5 8.9 13.6 4.6 7.4 2.2 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF342 PF03961.8 ETO25402.1 - 1.7 6.9 18.3 0.038 12.3 4.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF342) CBF_beta PF02312.12 ETO25402.1 - 2.1 7.9 8.2 0.15 11.6 0.5 2.3 1 1 1 2 2 2 0 Core binding factor beta subunit DUF972 PF06156.8 ETO25402.1 - 3.3 8.0 16.3 0.12 12.6 1.3 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF972) DUF607 PF04678.8 ETO25402.1 - 3.5 7.5 8.0 3 7.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF607 DUF4407 PF14362.1 ETO25402.1 - 3.9 6.3 9.8 2.3 7.0 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Spc24 PF08286.6 ETO25402.1 - 4.6 6.9 19.1 0.026 14.2 1.6 2.9 3 1 0 3 3 2 0 Spc24 subunit of Ndc80 DUF3086 PF11285.3 ETO25402.1 - 4.6 5.9 9.5 0.53 9.0 0.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3086) Bap31 PF05529.7 ETO25402.1 - 5.1 6.5 13.2 3.9 6.8 1.7 2.4 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like AAA_13 PF13166.1 ETO25402.1 - 5.2 5.4 22.2 0.43 8.9 5.4 2.4 2 1 0 2 2 2 0 AAA domain TMCO5 PF14992.1 ETO25402.1 - 5.7 5.9 18.6 0.55 9.3 1.3 2.5 3 0 0 3 3 3 0 TMCO5 family SlyX PF04102.7 ETO25402.1 - 6.1 7.2 14.8 0.65 10.4 4.7 2.6 2 1 0 2 2 2 0 SlyX V-SNARE PF05008.10 ETO25402.1 - 6.3 7.0 18.8 10 6.3 5.7 2.6 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Tropomyosin_1 PF12718.2 ETO25402.1 - 6.8 6.5 28.0 0.2 11.4 4.1 2.8 3 0 0 3 3 3 0 Tropomyosin like FemAB PF02388.11 ETO25402.1 - 8.8 4.8 15.4 0.41 9.2 2.1 2.2 2 0 0 2 2 2 0 FemAB family DUF2951 PF11166.3 ETO25402.1 - 8.9 6.2 11.8 4.4 7.2 0.1 3.1 3 1 0 3 3 2 0 Protein of unknown function (DUF2951) WD40 PF00400.27 ETO25404.1 - 1e-55 183.6 20.4 4.1e-13 48.6 0.1 7.5 7 1 1 8 8 8 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO25404.1 - 2.3e-08 34.0 0.2 0.0086 15.8 0.1 3.4 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO25404.1 - 1.1e-07 30.4 2.0 0.089 10.9 0.0 4.1 1 1 3 4 4 4 4 Nucleoporin Nup120/160 PD40 PF07676.7 ETO25404.1 - 1.8e-07 30.6 6.6 0.71 9.6 0.0 5.4 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO25404.1 - 1.8e-05 23.2 0.4 0.11 10.7 0.0 3.0 2 1 1 3 3 3 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO25404.1 - 0.00014 21.4 0.0 0.0045 16.4 0.0 2.2 2 0 0 2 2 2 1 PQQ-like domain Resistin PF06954.6 ETO25404.1 - 0.00028 21.0 0.1 3.3 8.0 0.0 3.6 2 1 1 3 3 3 2 Resistin Hira PF07569.6 ETO25404.1 - 0.00065 18.9 0.9 1.7 7.7 0.0 3.7 1 1 3 4 4 4 2 TUP1-like enhancer of split Proteasome_A_N PF10584.4 ETO25404.1 - 0.0029 16.8 6.2 2.7 7.3 0.0 4.3 4 0 0 4 4 4 1 Proteasome subunit A N-terminal signature Nucleoporin_N PF08801.6 ETO25404.1 - 0.0091 14.7 5.9 0.13 11.0 3.8 3.2 1 1 1 2 2 2 1 Nup133 N terminal like DUF2963 PF11178.3 ETO25404.1 - 0.011 15.1 0.4 8.6 5.8 0.0 3.7 4 1 0 4 4 4 0 Protein of unknown function (DUF2963) Coatomer_WDAD PF04053.9 ETO25404.1 - 0.03 13.1 0.8 0.38 9.4 0.1 2.4 1 1 3 4 4 4 0 Coatomer WD associated region DUF2415 PF10313.4 ETO25404.1 - 0.091 12.4 1.1 17 5.1 0.1 3.6 4 0 0 4 4 4 0 Uncharacterised protein domain (DUF2415) TFIIIC_delta PF12657.2 ETO25404.1 - 0.2 11.3 3.3 0.86 9.2 0.3 3.2 2 2 0 2 2 2 0 Transcription factor IIIC subunit delta N-term Kelch_6 PF13964.1 ETO25405.1 - 4e-05 23.5 0.9 0.0012 18.9 0.1 2.4 1 1 1 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO25405.1 - 0.0013 18.8 0.0 0.0029 17.7 0.0 1.6 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO25405.1 - 0.0015 18.2 2.1 0.16 11.7 0.0 2.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO25405.1 - 0.019 14.6 0.2 0.19 11.5 0.1 2.4 2 0 0 2 2 2 0 Kelch motif Kelch_1 PF01344.20 ETO25405.1 - 0.041 13.4 1.3 0.35 10.4 0.6 2.4 2 0 0 2 2 2 0 Kelch motif WD40 PF00400.27 ETO25406.1 - 1.7e-68 224.2 19.5 3.4e-13 48.9 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO25406.1 - 1.1e-12 48.1 1.0 0.0013 18.4 0.0 4.2 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO25406.1 - 1.2e-09 37.6 7.4 0.021 14.5 0.0 6.2 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO25406.1 - 3.5e-09 35.4 0.8 3.7e-05 22.1 0.0 3.3 2 1 2 4 4 4 3 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 ETO25406.1 - 2.5e-05 23.2 0.3 0.0039 16.0 0.1 2.1 1 1 1 2 2 2 2 Coatomer WD associated region Proteasome_A_N PF10584.4 ETO25406.1 - 9.4e-05 21.6 5.1 3 7.2 0.0 4.8 4 0 0 4 4 4 2 Proteasome subunit A N-terminal signature Nup160 PF11715.3 ETO25406.1 - 0.00025 19.3 7.8 0.15 10.1 0.4 3.9 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 ETO25406.1 - 0.00035 19.7 0.8 1.2 8.1 0.1 3.5 1 1 2 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 ETO25406.1 - 0.0041 15.9 7.9 1.5 7.4 1.6 4.2 1 1 1 2 2 2 2 Nup133 N terminal like Resistin PF06954.6 ETO25406.1 - 0.0048 17.1 1.6 5 7.4 0.0 3.7 2 2 0 3 3 3 1 Resistin DUF1258 PF06869.7 ETO25406.1 - 0.019 14.0 3.1 13 4.7 0.0 3.8 2 1 2 4 4 4 0 Protein of unknown function (DUF1258) Strep_his_triad PF04270.8 ETO25406.1 - 0.051 13.3 0.0 0.98 9.1 0.0 2.3 2 0 0 2 2 2 0 Streptococcal histidine triad protein GSDH PF07995.6 ETO25406.1 - 0.077 12.0 0.0 14 4.5 0.0 2.8 2 1 1 3 3 3 0 Glucose / Sorbosone dehydrogenase Jiv90 PF14901.1 ETO25406.1 - 0.079 12.9 0.2 0.43 10.5 0.1 2.1 2 0 0 2 2 2 0 Cleavage inducing molecular chaperone Colicin_C PF12106.3 ETO25406.1 - 1.9 8.1 4.7 1.9 8.1 0.6 2.8 3 0 0 3 3 3 0 Colicin C terminal ribonuclease domain SBDS PF01172.13 ETO25407.1 - 1.8e-24 85.3 0.1 4.2e-24 84.1 0.1 1.7 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.5 ETO25407.1 - 3.5e-17 62.2 0.4 4.7e-17 61.8 0.0 1.5 2 0 0 2 2 2 1 SBDS protein C-terminal domain SICA_beta PF12878.2 ETO25409.1 - 0.059 13.1 8.5 0.082 12.7 5.9 1.3 1 1 0 1 1 1 0 SICA extracellular beta domain TSC21 PF15217.1 ETO25409.1 - 0.14 11.8 0.5 0.16 11.6 0.4 1.0 1 0 0 1 1 1 0 TSC21 family PPO1_KFDV PF12143.3 ETO25409.1 - 0.2 11.5 4.7 0.25 11.2 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF_B2219) Tox-REase-2 PF15646.1 ETO25409.1 - 5.7 6.8 6.9 2.5 8.0 2.5 1.8 1 1 1 2 2 2 0 Restriction endonuclease fold toxin 2 Borrelia_P83 PF05262.6 ETO25409.1 - 7.8 4.6 19.8 9.1 4.4 13.7 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein PQQ_3 PF13570.1 ETO25410.1 - 0.043 14.1 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 PQQ-like domain MMS1_N PF10433.4 ETO25410.1 - 0.08 11.0 0.0 0.1 10.6 0.0 1.2 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term YscJ_FliF_C PF08345.6 ETO25411.1 - 0.055 13.4 7.2 0.073 13.0 5.0 1.2 1 0 0 1 1 1 0 Flagellar M-ring protein C-terminal RR_TM4-6 PF06459.7 ETO25411.1 - 1.5 8.6 9.1 1.9 8.3 6.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Myc_N PF01056.13 ETO25411.1 - 6.2 5.8 13.3 11 5.0 9.0 1.6 1 1 0 1 1 1 0 Myc amino-terminal region NAM-associated PF14303.1 ETO25412.1 - 0.15 12.4 14.3 0.35 11.1 9.9 1.6 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain WD40 PF00400.27 ETO25413.1 - 1.2e-05 24.9 0.0 0.00043 20.0 0.0 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat Kelch_4 PF13418.1 ETO25414.1 - 3.2e-06 26.8 6.2 3 7.6 0.1 5.5 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO25414.1 - 5.4e-06 25.9 6.0 0.83 9.5 0.0 5.5 5 0 0 5 5 5 1 Kelch motif Kelch_5 PF13854.1 ETO25414.1 - 1.3e-05 24.9 19.2 0.056 13.4 0.0 5.5 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.1 ETO25414.1 - 0.0044 17.1 19.1 4.4 7.6 0.1 5.9 6 0 0 6 6 6 2 Kelch motif Kelch_3 PF13415.1 ETO25414.1 - 0.012 15.8 4.4 2.6 8.3 0.1 4.4 5 0 0 5 5 5 0 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO25414.1 - 0.096 12.2 16.9 0.16 11.5 0.1 4.9 4 1 0 4 4 4 0 Kelch motif MIP-T3 PF10243.4 ETO25414.1 - 6.3 5.1 74.6 8.6 4.7 51.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Epimerase PF01370.16 ETO25415.1 - 5e-24 85.0 0.0 7.1e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETO25415.1 - 2.4e-13 49.4 0.0 4.2e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 ETO25415.1 - 4.6e-13 48.7 0.0 7.2e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 ETO25415.1 - 4.1e-07 29.1 0.0 1.7e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 ETO25415.1 - 0.00034 19.6 0.0 0.0046 15.9 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 ETO25415.1 - 0.041 13.7 0.0 0.19 11.6 0.0 1.9 1 1 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 ETO25415.1 - 0.052 13.2 0.0 0.17 11.4 0.0 1.8 1 1 0 1 1 1 0 KR domain Ubiquitin_2 PF14560.1 ETO25416.1 - 0.024 14.8 0.2 0.045 14.0 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain CASP_C PF08172.7 ETO25417.1 - 0.079 11.9 7.1 0.16 11.0 5.0 1.5 1 1 0 1 1 1 0 CASP C terminal Dor1 PF04124.7 ETO25417.1 - 0.083 11.3 7.5 0.11 10.9 5.2 1.2 1 0 0 1 1 1 0 Dor1-like family APG6 PF04111.7 ETO25417.1 - 0.16 10.9 9.9 0.24 10.3 6.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 GAGA_bind PF06217.7 ETO25417.1 - 1.1 9.2 8.0 1.4 8.8 5.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF972 PF06156.8 ETO25417.1 - 5.4 7.4 14.2 0.93 9.8 2.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF972) KapB PF08810.5 ETO25418.1 - 0.021 14.8 2.2 0.19 11.7 0.1 2.6 2 1 0 2 2 2 0 Kinase associated protein B DUF972 PF06156.8 ETO25418.1 - 1.4 9.2 7.8 1.5 9.1 3.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) CENP-K PF11802.3 ETO25419.1 - 0.002 17.3 3.9 0.0022 17.2 2.7 1.2 1 0 0 1 1 1 1 Centromere-associated protein K Striatin PF08232.7 ETO25420.1 - 0.84 9.9 19.6 43 4.4 13.6 2.9 1 1 0 1 1 1 0 Striatin family SlyX PF04102.7 ETO25420.1 - 1.3 9.4 9.9 0.9 9.9 0.7 2.3 2 0 0 2 2 2 0 SlyX Pex24p PF06398.6 ETO25421.1 - 0.0046 15.8 0.6 0.0075 15.1 0.4 1.3 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin Shisa PF13908.1 ETO25421.1 - 0.014 15.5 1.0 0.02 15.1 0.1 1.8 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF3796 PF12676.2 ETO25421.1 - 0.065 13.4 0.7 0.13 12.5 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) Menin PF05053.8 ETO25421.1 - 0.07 11.2 7.2 0.094 10.8 5.0 1.2 1 0 0 1 1 1 0 Menin Peptidase_S49_N PF08496.5 ETO25421.1 - 0.33 10.7 14.5 0.91 9.3 2.2 2.6 1 1 1 2 2 2 0 Peptidase family S49 N-terminal CAAD PF14159.1 ETO25421.1 - 0.36 10.5 5.6 0.73 9.5 3.8 1.5 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Tetraspannin PF00335.15 ETO25421.1 - 1.4 8.1 7.4 0.049 12.9 0.7 1.8 2 0 0 2 2 2 0 Tetraspanin family Daxx PF03344.10 ETO25421.1 - 2.2 6.6 28.0 3.5 6.0 19.4 1.3 1 0 0 1 1 1 0 Daxx Family DUF4446 PF14584.1 ETO25421.1 - 5 6.9 10.0 0.27 11.0 0.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) Astro_capsid PF03115.9 ETO25421.1 - 8.3 4.5 15.3 9.6 4.3 10.6 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Vpu PF00558.14 ETO25421.1 - 9.9 5.8 11.5 0.097 12.2 0.9 2.5 2 0 0 2 2 2 0 Vpu protein RRM_1 PF00076.17 ETO25422.1 - 0.00073 19.1 0.0 0.0019 17.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO25422.1 - 0.083 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) TAXi_N PF14543.1 ETO25422.1 - 0.39 10.6 5.6 0.064 13.1 0.9 1.8 2 0 0 2 2 2 0 Xylanase inhibitor N-terminal RunxI PF08504.6 ETO25423.1 - 0.79 10.2 3.3 0.57 10.6 0.6 1.8 1 1 1 2 2 2 0 Runx inhibition domain IF-2B PF01008.12 ETO25424.1 - 0.98 8.3 6.2 0.14 11.1 0.8 1.9 1 1 1 2 2 2 0 Initiation factor 2 subunit family DUF4140 PF13600.1 ETO25424.1 - 1.5 9.3 6.6 9.9 6.6 0.4 2.6 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) FRG2 PF15315.1 ETO25425.1 - 0.018 15.0 3.6 0.018 15.0 2.5 2.2 2 0 0 2 2 2 0 Facioscapulohumeral muscular dystrophy candidate 2 TMEM51 PF15345.1 ETO25425.1 - 6.1 6.4 9.8 1.5 8.4 3.4 2.0 2 0 0 2 2 2 0 Transmembrane protein 51 PSCyt3 PF07627.6 ETO25425.1 - 8.3 6.3 8.3 1.8 8.4 0.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1588) Arteri_Gl PF00951.13 ETO25426.1 - 0.19 11.3 2.9 0.4 10.2 2.0 1.5 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein Ank_2 PF12796.2 ETO25428.1 - 1.3e-05 25.4 0.0 2.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO25428.1 - 1.7e-05 25.1 0.1 0.17 12.4 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 ETO25428.1 - 2e-05 24.1 0.0 0.2 11.5 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 ETO25428.1 - 0.0036 17.3 0.1 0.38 11.1 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Daxx PF03344.10 ETO25428.1 - 0.32 9.4 10.3 0.39 9.1 7.1 1.1 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 ETO25428.1 - 0.67 8.6 11.7 0.8 8.3 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 ETO25428.1 - 2.7 5.8 10.4 3.2 5.5 7.2 1.1 1 0 0 1 1 1 0 Nop14-like family Peptidase_C14 PF00656.17 ETO25430.1 - 5.3e-10 39.4 1.3 9.8e-10 38.5 0.9 1.4 1 1 0 1 1 1 1 Caspase domain DUF1481 PF07356.7 ETO25430.1 - 0.093 12.1 0.2 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1481) Macoilin PF09726.4 ETO25431.1 - 0.028 12.7 5.5 0.028 12.7 3.8 1.1 1 0 0 1 1 1 0 Transmembrane protein CDC45 PF02724.9 ETO25431.1 - 0.045 11.7 7.3 0.045 11.7 5.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.3 ETO25431.1 - 0.41 9.1 3.1 0.5 8.9 2.1 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RR_TM4-6 PF06459.7 ETO25431.1 - 0.98 9.2 8.6 1.3 8.8 5.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 ETO25431.1 - 1.7 7.9 14.9 2.4 7.4 10.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Mucin PF01456.12 ETO25432.1 - 0.03 14.1 12.7 0.058 13.1 8.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein PBP1_TM PF14812.1 ETO25432.1 - 0.15 12.3 0.0 0.15 12.3 0.0 5.0 4 1 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal IPP-2 PF04979.9 ETO25433.1 - 0.0028 17.9 4.0 0.0028 17.9 1.8 1.6 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) GluR_Homer-bdg PF10606.4 ETO25433.1 - 0.062 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Homer-binding domain of metabotropic glutamate receptor 7tm_3 PF00003.17 ETO25434.1 - 2.9e-24 85.7 26.8 4e-24 85.2 18.6 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Chlam_PMP PF02415.12 ETO25434.1 - 0.00013 22.0 48.3 0.93 9.8 0.0 12.5 14 0 0 14 14 14 4 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Humanin PF15040.1 ETO25434.1 - 0.69 9.2 2.5 1.6 8.0 1.8 1.5 1 0 0 1 1 1 0 Humanin family Pkinase PF00069.20 ETO25435.1 - 4.8e-23 81.6 0.0 5.6e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO25435.1 - 1.5e-17 63.5 0.0 1.8e-17 63.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO25435.1 - 5.6e-05 22.2 0.1 0.00011 21.3 0.0 1.4 1 1 0 1 1 1 1 Kinase-like ABC2_membrane PF01061.19 ETO25436.1 - 2.8e-20 72.4 9.9 2.8e-20 72.4 6.8 2.0 1 1 1 2 2 2 1 ABC-2 type transporter p53-inducible11 PF14936.1 ETO25436.1 - 0.19 11.6 4.2 0.26 11.2 0.1 2.6 2 1 1 3 3 3 0 Tumour protein p53-inducible protein 11 DUF912 PF06024.7 ETO25436.1 - 0.82 9.7 6.3 0.49 10.4 0.4 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Rhomboid PF01694.17 ETO25436.1 - 3.2 7.7 12.2 2.5 8.1 5.1 2.6 2 1 0 2 2 2 0 Rhomboid family ABC2_membrane_3 PF12698.2 ETO25437.1 - 0.00012 21.3 5.3 0.00015 20.9 3.7 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ATG27 PF09451.5 ETO25437.1 - 0.00039 19.7 0.6 0.00051 19.3 0.4 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 DUF912 PF06024.7 ETO25437.1 - 0.0011 19.0 7.1 0.0011 19.0 4.9 2.2 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) T2SF PF00482.18 ETO25437.1 - 0.0081 16.0 2.9 0.017 15.0 2.0 1.5 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F Tetraspannin PF00335.15 ETO25437.1 - 0.011 15.0 6.2 0.015 14.6 4.3 1.4 1 1 0 1 1 1 0 Tetraspanin family Baculo_E56 PF04639.7 ETO25437.1 - 0.011 14.3 9.7 0.015 13.9 6.7 1.3 1 1 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope DUF4448 PF14610.1 ETO25437.1 - 0.035 13.5 3.2 0.054 12.9 2.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4448) Vma12 PF11712.3 ETO25437.1 - 0.097 12.3 4.5 0.14 11.8 3.1 1.4 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Scs3p PF10261.4 ETO25437.1 - 0.42 9.5 4.8 0.13 11.2 1.3 1.6 1 1 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Shisa PF13908.1 ETO25437.1 - 1.3 9.2 10.5 0.2 11.8 3.6 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator TMEM154 PF15102.1 ETO25437.1 - 1.3 8.7 20.4 9.5 5.9 14.1 2.0 1 1 0 1 1 1 0 TMEM154 protein family Protocadherin PF08374.6 ETO25437.1 - 1.5 8.3 12.8 1.3 8.6 3.4 2.1 2 0 0 2 2 2 0 Protocadherin DUF3796 PF12676.2 ETO25437.1 - 2.9 8.1 8.5 4.6 7.4 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) Afaf PF15339.1 ETO25437.1 - 4.2 6.9 7.9 10 5.6 5.5 1.6 1 1 0 1 1 1 0 Acrosome formation-associated factor Plant_vir_prot PF01307.12 ETO25437.1 - 7.1 6.4 8.8 46 3.8 6.1 2.2 1 1 0 1 1 1 0 Plant viral movement protein EssA PF10661.4 ETO25437.1 - 8.1 6.1 11.2 1.8 8.2 4.4 2.0 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA NT-C2 PF10358.4 ETO25439.1 - 1.2e-05 24.8 0.2 1.4e-05 24.6 0.2 1.1 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins WEMBL PF05701.6 ETO25440.1 - 0.0061 15.0 25.8 0.011 14.2 17.9 1.4 1 0 0 1 1 1 1 Weak chloroplast movement under blue light TMF_DNA_bd PF12329.3 ETO25440.1 - 0.18 11.6 32.3 0.35 10.6 0.3 4.7 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 ETO25440.1 - 0.24 10.4 37.5 0.06 12.3 12.2 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 Myosin_tail_1 PF01576.14 ETO25440.1 - 0.82 7.3 33.2 0.48 8.0 17.8 2.7 2 1 1 3 3 3 0 Myosin tail Reo_sigmaC PF04582.7 ETO25440.1 - 2.1 7.4 10.7 0.9 8.6 5.0 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 ETO25440.1 - 3.4 7.5 38.7 0.14 12.0 8.1 3.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 ETO25440.1 - 4.6 7.0 42.1 0.042 13.6 10.0 3.0 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Mto2_bdg PF12808.2 ETO25440.1 - 5.5 7.1 13.2 18 5.5 0.6 4.1 2 1 1 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Filament PF00038.16 ETO25440.1 - 7.3 5.9 32.9 42 3.4 22.8 2.3 1 1 0 1 1 1 0 Intermediate filament protein DUF1664 PF07889.7 ETO25440.1 - 8.3 6.2 16.2 0.3 10.8 4.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DivIC PF04977.10 ETO25440.1 - 9.9 5.7 27.3 7.4 6.1 2.3 5.3 2 1 3 5 5 5 0 Septum formation initiator TIM PF00121.13 ETO25441.1 - 0.022 13.8 1.2 0.027 13.5 0.8 1.1 1 0 0 1 1 1 0 Triosephosphate isomerase L1R_F9L PF02442.12 ETO25441.1 - 0.029 13.8 3.3 0.04 13.3 2.1 1.3 1 1 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses Bromodomain PF00439.20 ETO25441.1 - 0.035 14.0 0.8 0.059 13.3 0.5 1.4 1 0 0 1 1 1 0 Bromodomain COG5 PF10392.4 ETO25441.1 - 0.048 13.6 0.8 0.12 12.3 0.3 1.8 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DUF2361 PF10153.4 ETO25441.1 - 0.053 13.7 6.9 0.033 14.3 3.6 1.5 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) Phage_lysis PF03245.8 ETO25441.1 - 0.06 13.3 0.8 0.11 12.4 0.6 1.6 1 1 0 1 1 1 0 Bacteriophage Rz lysis protein Noelin-1 PF12308.3 ETO25441.1 - 0.11 12.3 1.8 0.28 11.0 0.1 2.2 1 1 2 3 3 3 0 Neurogenesis glycoprotein Reo_sigmaC PF04582.7 ETO25441.1 - 0.11 11.6 0.5 0.14 11.2 0.4 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 ETO25441.1 - 0.15 11.8 3.4 0.24 11.2 1.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Trypan_PARP PF05887.6 ETO25442.1 - 4.1 7.2 16.2 6.7 6.5 11.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GCV_T PF01571.16 ETO25443.1 - 3.4e-62 209.5 0.0 5e-62 209.0 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 ETO25443.1 - 5.2e-20 71.2 0.1 8.5e-20 70.5 0.1 1.3 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain WD40 PF00400.27 ETO25443.1 - 7e-06 25.7 3.3 0.00015 21.4 0.2 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO25443.1 - 0.015 13.4 0.1 0.021 12.9 0.1 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 B2-adapt-app_C PF09066.5 ETO25444.1 - 9.4e-08 31.9 0.1 1.3e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain Trehalose_recp PF06151.8 ETO25444.1 - 0.087 11.1 1.3 1.2 7.4 0.1 2.0 1 1 1 2 2 2 0 Trehalose receptor SOBP PF15279.1 ETO25446.1 - 7.6 6.8 26.4 9.7 6.4 18.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Peptidase_C14 PF00656.17 ETO25447.1 - 1.2e-11 44.8 0.3 1.9e-11 44.1 0.2 1.3 1 0 0 1 1 1 1 Caspase domain Kelch_6 PF13964.1 ETO25449.1 - 0.0053 16.8 3.6 0.54 10.5 0.1 3.4 4 0 0 4 4 4 2 Kelch motif XPA_C PF05181.7 ETO25449.1 - 0.035 13.6 0.0 0.088 12.4 0.0 1.6 1 0 0 1 1 1 0 XPA protein C-terminus Kelch_5 PF13854.1 ETO25449.1 - 4.4 7.3 9.9 3.3 7.7 0.2 3.7 4 0 0 4 4 4 0 Kelch motif WD40 PF00400.27 ETO25450.1 - 7.2e-95 307.8 17.6 4.9e-14 51.5 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO25450.1 - 1.6e-16 60.5 6.2 6.6e-05 22.6 0.0 3.8 1 1 4 5 5 5 5 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO25450.1 - 2.6e-10 39.0 5.4 0.025 12.7 0.0 5.5 1 1 5 6 6 6 5 Nucleoporin Nup120/160 Str_synth PF03088.11 ETO25450.1 - 2e-05 24.5 0.0 0.84 9.7 0.0 3.9 2 1 1 3 3 3 2 Strictosidine synthase Nucleoporin_N PF08801.6 ETO25450.1 - 4e-05 22.5 9.1 0.14 10.8 0.2 5.4 1 1 3 4 4 4 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO25450.1 - 5.2e-05 21.7 1.7 0.97 7.6 0.1 3.7 1 1 4 5 5 5 4 Cytochrome D1 heme domain DUF3892 PF13031.1 ETO25450.1 - 0.00011 22.5 3.0 0.18 12.2 0.0 3.7 4 2 0 4 4 3 2 Protein of unknown function (DUF3892) DUF1258 PF06869.7 ETO25450.1 - 0.00096 18.3 0.2 0.23 10.5 0.0 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF1258) Gmad1 PF10647.4 ETO25450.1 - 0.03 13.7 0.0 0.95 8.8 0.0 2.3 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain DUF1002 PF06207.6 ETO25450.1 - 0.063 12.5 1.0 0.13 11.5 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) PD40 PF07676.7 ETO25450.1 - 0.2 11.3 11.4 11 5.7 0.0 5.6 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Mid2 PF04478.7 ETO25450.1 - 0.39 10.1 3.9 9.1 5.6 0.0 3.7 5 0 0 5 5 5 0 Mid2 like cell wall stress sensor Proteasome_A_N PF10584.4 ETO25450.1 - 1.7 8.0 9.3 54 3.2 0.1 5.1 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature FmdE PF02663.9 ETO25450.1 - 5.8 6.8 7.2 1.1 9.1 0.1 2.6 2 1 0 3 3 3 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon EF-hand_1 PF00036.27 ETO25451.1 - 0.017 14.4 0.1 0.065 12.5 0.0 2.1 1 0 0 1 1 1 0 EF hand IncA PF04156.9 ETO25451.1 - 0.03 13.9 0.4 0.047 13.2 0.3 1.3 1 0 0 1 1 1 0 IncA protein IR1-M PF12185.3 ETO25451.1 - 0.053 13.2 0.1 0.19 11.4 0.1 1.9 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain P22_Tail-4 PF11650.3 ETO25451.1 - 0.064 12.8 0.1 0.27 10.7 0.0 1.9 2 0 0 2 2 2 0 P22 tail accessory factor AdoMet_dc PF02675.10 ETO25451.1 - 0.11 12.3 0.0 0.46 10.4 0.0 2.0 1 0 0 1 1 1 0 S-adenosylmethionine decarboxylase Pox_A_type_inc PF04508.7 ETO25451.1 - 1.2 9.0 3.9 0.88 9.5 0.3 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat ECH PF00378.15 ETO25452.1 - 5.2e-29 101.0 0.1 6.8e-29 100.7 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family tRNA_U5-meth_tr PF05958.6 ETO25453.1 - 7e-11 41.4 0.0 1.4e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 ETO25453.1 - 3e-10 39.8 0.1 1.9e-09 37.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETO25453.1 - 0.00026 21.0 0.0 0.0004 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETO25453.1 - 0.00033 20.0 0.0 0.00066 19.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 ETO25453.1 - 0.0035 17.6 0.0 0.059 13.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETO25453.1 - 0.023 13.8 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 ETO25453.1 - 0.031 14.8 0.0 0.065 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Mannitol_dh_C PF08125.8 ETO25453.1 - 0.1 11.7 0.0 9.1 5.3 0.0 2.3 2 0 0 2 2 2 0 Mannitol dehydrogenase C-terminal domain Med3 PF11593.3 ETO25454.1 - 0.022 14.0 35.7 0.035 13.3 24.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2937 PF11157.3 ETO25455.1 - 0.076 12.3 2.2 3.4 6.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) MHC2-interact PF09307.5 ETO25455.1 - 3.9 7.2 12.1 2 8.2 1.7 3.0 1 1 1 2 2 2 0 CLIP, MHC2 interacting G-alpha PF00503.15 ETO25456.1 - 1.6e-42 145.6 29.9 1.9e-41 142.0 20.7 2.0 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO25456.1 - 4.2e-07 29.3 1.9 2.4e-06 26.8 0.1 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family Afaf PF15339.1 ETO25456.1 - 9.7 5.7 8.4 34 3.9 3.4 2.3 2 0 0 2 2 2 0 Acrosome formation-associated factor SynMuv_product PF06047.6 ETO25457.1 - 2.5e-47 158.9 2.7 2.5e-47 158.9 1.8 3.9 4 0 0 4 4 4 1 Ras-induced vulval development antagonist Myco_19_kDa PF05481.7 ETO25457.1 - 1.6 8.5 15.0 0.058 13.2 0.6 2.5 2 0 0 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen RUN PF02759.14 ETO25458.1 - 0.00053 19.7 0.9 0.00094 18.9 0.1 1.8 2 0 0 2 2 2 1 RUN domain YL1 PF05764.8 ETO25458.1 - 0.078 12.5 26.4 0.13 11.9 18.3 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Herpes_LMP1 PF05297.6 ETO25458.1 - 0.83 8.5 13.5 1 8.1 9.3 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) GAGA_bind PF06217.7 ETO25458.1 - 1.3 8.9 19.9 2 8.3 13.8 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4206 PF13901.1 ETO25459.1 - 1.6e-37 129.0 20.9 1.6e-37 129.0 14.5 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4206) TF_Zn_Ribbon PF08271.7 ETO25459.1 - 0.003 16.8 2.7 0.003 16.8 1.9 2.5 2 0 0 2 2 2 1 TFIIB zinc-binding C1_1 PF00130.17 ETO25459.1 - 3.8 7.3 33.8 1.9 8.2 3.2 3.6 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HALZ PF02183.13 ETO25460.1 - 2.2e-05 24.0 20.5 0.059 13.0 1.7 3.5 3 0 0 3 3 3 3 Homeobox associated leucine zipper DUF2999 PF11212.3 ETO25460.1 - 0.17 11.9 3.6 0.27 11.3 1.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2999) ADIP PF11559.3 ETO25460.1 - 0.23 11.3 36.0 0.12 12.3 18.8 2.9 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF3584 PF12128.3 ETO25460.1 - 0.26 8.5 26.9 0.33 8.2 18.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.7 ETO25460.1 - 0.67 9.7 33.9 0.039 13.6 5.6 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein GAS PF13851.1 ETO25460.1 - 1.7 7.7 34.0 4.3 6.4 18.2 3.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Striatin PF08232.7 ETO25460.1 - 3.1 8.1 28.6 0.69 10.2 6.2 3.1 1 1 2 3 3 3 0 Striatin family FlaC_arch PF05377.6 ETO25460.1 - 4.1 7.3 13.7 4 7.3 1.3 4.0 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Acetyltransf_11 PF13720.1 ETO25460.1 - 5.7 7.2 6.0 4.6 7.5 0.5 2.6 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF972 PF06156.8 ETO25460.1 - 6.9 7.0 30.3 0.76 10.1 1.1 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DUF4407 PF14362.1 ETO25460.1 - 9.4 5.0 24.8 0.57 9.0 9.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF3391 PF11871.3 ETO25462.1 - 1.3 9.2 4.1 0.66 10.1 1.2 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) NAAA-beta PF15508.1 ETO25463.1 - 0.031 14.6 0.2 0.11 12.8 0.1 1.8 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Bcl-2 PF00452.14 ETO25463.1 - 0.092 12.8 0.8 1.1 9.4 0.1 2.1 1 1 1 2 2 2 0 Apoptosis regulator proteins, Bcl-2 family Peptidase_C14 PF00656.17 ETO25464.1 - 2.7e-08 33.7 0.3 3.8e-08 33.3 0.2 1.2 1 0 0 1 1 1 1 Caspase domain P22_AR_N PF10547.4 ETO25464.1 - 0.043 13.6 0.2 0.14 12.0 0.1 1.9 1 1 1 2 2 2 0 P22_AR N-terminal domain Paramyxo_PCT PF14320.1 ETO25465.1 - 0.032 13.1 0.0 0.039 12.8 0.0 1.0 1 0 0 1 1 1 0 Phosphoprotein P region PCT disordered Vma12 PF11712.3 ETO25466.1 - 0.0061 16.2 4.0 0.0088 15.7 2.8 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase TRAP_alpha PF03896.11 ETO25466.1 - 0.032 13.2 0.3 0.039 12.9 0.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sec62 PF03839.11 ETO25466.1 - 1.1 8.5 6.2 1.4 8.2 4.3 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Tmemb_9 PF05434.6 ETO25466.1 - 2 8.1 7.2 2.1 8.0 3.4 2.0 2 0 0 2 2 2 0 TMEM9 RRM_6 PF14259.1 ETO25468.1 - 3e-10 39.9 0.0 2.2e-07 30.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO25468.1 - 2.2e-09 36.8 0.2 2.5e-08 33.4 0.0 2.7 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO25468.1 - 1.2e-06 28.2 1.5 0.0015 18.3 0.0 3.4 3 1 1 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO25469.1 - 5.4e-05 23.0 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AIP3 PF03915.8 ETO25469.1 - 0.00017 20.6 2.1 0.00022 20.2 1.5 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 Pox_E10 PF04805.7 ETO25469.1 - 0.0063 16.0 0.1 0.02 14.3 0.0 1.9 1 0 0 1 1 1 1 E10-like protein conserved region RRM_1 PF00076.17 ETO25469.1 - 0.032 13.8 0.1 0.13 11.9 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UN_NPL4 PF11543.3 ETO25469.1 - 0.091 13.0 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 RRM_6 PF14259.1 ETO25470.1 - 0.0036 17.2 0.0 0.25 11.3 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO25470.1 - 0.0045 16.5 0.0 1.4 8.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kinesin PF00225.18 ETO25472.1 - 2.4e-43 148.1 0.0 4.3e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Reo_sigmaC PF04582.7 ETO25473.1 - 0.013 14.7 4.8 0.15 11.2 0.0 3.1 1 1 2 3 3 3 0 Reovirus sigma C capsid protein SSrecog PF03531.9 ETO25474.1 - 3.2e-34 118.2 8.4 2.9e-12 46.4 0.3 4.3 3 1 1 4 4 4 4 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 ETO25474.1 - 1.7e-22 79.2 1.8 2.8e-22 78.5 0.1 2.3 3 0 0 3 3 3 1 Histone chaperone Rttp106-like Sulfatase PF00884.18 ETO25475.1 - 1.8e-19 70.0 0.5 3.7e-19 69.0 0.0 1.6 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 ETO25475.1 - 0.0014 18.0 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Dsh_C PF12316.3 ETO25476.1 - 0.91 9.6 5.5 1 9.4 3.8 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Neur_chan_memb PF02932.11 ETO25476.1 - 2.2 8.0 5.9 2.3 8.0 4.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4512 PF14975.1 ETO25476.1 - 2.5 9.0 7.4 3.2 8.6 5.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) DDHD PF02862.12 ETO25476.1 - 4.7 6.9 8.6 5.3 6.7 6.0 1.1 1 0 0 1 1 1 0 DDHD domain RNA_polI_A34 PF08208.6 ETO25476.1 - 8.5 5.9 23.5 10 5.7 16.3 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RhoGAP PF00620.22 ETO25477.1 - 3.9e-17 62.2 0.0 4.9e-15 55.4 0.0 2.3 1 1 0 1 1 1 1 RhoGAP domain Peptidase_M50 PF02163.17 ETO25477.1 - 0.31 9.9 2.8 0.7 8.8 0.1 2.1 2 0 0 2 2 2 0 Peptidase family M50 Myc_N PF01056.13 ETO25478.1 - 0.037 13.1 1.3 0.049 12.7 0.9 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF1033 PF06279.6 ETO25478.1 - 0.14 11.9 3.5 0.29 10.9 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) DRY_EERY PF09750.4 ETO25478.1 - 0.59 10.2 4.8 0.98 9.5 3.4 1.3 1 0 0 1 1 1 0 Alternative splicing regulator DUF2345 PF10106.4 ETO25479.1 - 3.9e-19 68.7 2.9 0.18 11.4 0.0 8.7 1 1 8 9 9 9 9 Uncharacterized protein conserved in bacteria (DUF2345) Gp5_C PF06715.7 ETO25479.1 - 1.4e-06 27.7 95.7 0.015 15.1 0.7 14.8 13 2 3 17 17 17 11 Gp5 C-terminal repeat (3 copies) PT PF04886.7 ETO25480.1 - 5.2e-07 28.8 45.0 0.0004 19.6 5.5 5.4 3 1 1 4 4 4 2 PT repeat DUF4106 PF13388.1 ETO25480.1 - 0.75 8.6 8.8 1.2 7.9 6.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Glycoprotein_G PF00802.14 ETO25480.1 - 1.1 8.3 27.5 2.5 7.1 19.1 1.7 1 1 0 1 1 1 0 Pneumovirus attachment glycoprotein G LCM PF04072.9 ETO25482.1 - 6.5e-18 64.9 0.0 1.7e-17 63.5 0.0 1.6 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase DUF1510 PF07423.6 ETO25483.1 - 0.0002 20.8 12.1 0.00023 20.5 8.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Kei1 PF08552.6 ETO25483.1 - 0.00026 20.7 0.4 0.00041 20.0 0.2 1.2 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 CDC45 PF02724.9 ETO25483.1 - 0.0057 14.7 6.3 0.0063 14.6 4.3 1.0 1 0 0 1 1 1 1 CDC45-like protein CobT PF06213.7 ETO25483.1 - 0.0079 15.3 7.6 0.0087 15.2 5.3 1.1 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT MecA PF05389.7 ETO25483.1 - 0.012 15.1 9.2 0.015 14.8 6.4 1.1 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) DUF2201_N PF13203.1 ETO25483.1 - 0.022 13.9 2.7 0.026 13.6 1.8 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain NPR3 PF03666.8 ETO25483.1 - 0.031 12.8 7.8 0.039 12.4 5.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM176 PF14851.1 ETO25483.1 - 0.034 13.8 3.8 0.054 13.1 2.7 1.3 1 0 0 1 1 1 0 FAM176 family Hid1 PF12722.2 ETO25483.1 - 0.042 11.5 8.1 0.043 11.5 5.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Apt1 PF10351.4 ETO25483.1 - 0.068 12.0 9.9 0.087 11.6 6.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF913 PF06025.7 ETO25483.1 - 0.081 11.6 4.4 0.096 11.4 3.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SID-1_RNA_chan PF13965.1 ETO25483.1 - 0.17 10.0 2.9 0.19 9.8 2.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Peptidase_S49_N PF08496.5 ETO25483.1 - 0.21 11.3 2.7 0.31 10.8 1.8 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ndc1_Nup PF09531.5 ETO25483.1 - 0.23 9.8 1.8 0.23 9.8 1.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DDHD PF02862.12 ETO25483.1 - 0.24 11.1 8.2 0.32 10.7 5.7 1.1 1 0 0 1 1 1 0 DDHD domain Ureide_permease PF07168.6 ETO25483.1 - 0.28 9.8 1.0 0.35 9.4 0.7 1.1 1 0 0 1 1 1 0 Ureide permease Zip PF02535.17 ETO25483.1 - 0.29 10.0 3.0 0.33 9.9 2.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Sigma70_ner PF04546.8 ETO25483.1 - 0.43 10.1 10.0 0.75 9.3 6.9 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region POX PF07526.6 ETO25483.1 - 0.54 10.4 5.9 0.87 9.8 4.1 1.4 1 0 0 1 1 1 0 Associated with HOX Serinc PF03348.10 ETO25483.1 - 0.94 8.1 3.5 1.1 7.8 2.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Vfa1 PF08432.5 ETO25483.1 - 0.97 9.4 15.0 1.4 8.9 10.4 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3537 PF12056.3 ETO25483.1 - 1.4 7.5 3.9 1.7 7.2 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) Presenilin PF01080.12 ETO25483.1 - 1.4 7.6 6.0 1.6 7.4 4.1 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.11 ETO25483.1 - 2.3 8.0 4.5 2.7 7.7 3.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Tim54 PF11711.3 ETO25483.1 - 2.4 6.6 8.6 2.9 6.3 6.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RP-C_C PF11800.3 ETO25483.1 - 4.5 6.9 11.7 6.2 6.4 8.1 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF4512 PF14975.1 ETO25483.1 - 5.4 7.9 7.7 11 6.9 5.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4512) Sec62 PF03839.11 ETO25483.1 - 5.4 6.3 8.6 7 5.9 5.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Anoctamin PF04547.7 ETO25487.1 - 6.6e-96 321.7 8.8 8.6e-96 321.3 6.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF106 PF01956.11 ETO25487.1 - 0.00013 21.5 0.1 0.00052 19.6 0.1 2.1 1 1 0 1 1 1 1 Integral membrane protein DUF106 AAA PF00004.24 ETO25488.1 - 2.1e-74 247.9 0.0 8.7e-45 152.1 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 ETO25488.1 - 2.7e-09 37.1 0.3 0.0079 16.1 0.0 3.6 3 1 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 ETO25488.1 - 3.9e-07 30.2 0.0 0.024 14.7 0.0 3.3 2 1 0 3 3 3 2 AAA domain AAA_16 PF13191.1 ETO25488.1 - 8.2e-07 29.1 0.4 0.00021 21.3 0.0 3.3 3 1 1 4 4 3 1 AAA ATPase domain AAA_14 PF13173.1 ETO25488.1 - 1.2e-05 25.1 0.0 0.013 15.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 ETO25488.1 - 3e-05 23.2 0.0 0.00033 19.7 0.0 2.5 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 ETO25488.1 - 3.2e-05 23.6 0.2 0.036 13.7 0.0 3.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 ETO25488.1 - 4.6e-05 22.9 1.4 0.025 13.9 0.1 3.0 2 2 1 3 3 3 2 AAA domain AAA_19 PF13245.1 ETO25488.1 - 0.0014 18.3 0.0 0.004 16.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 ETO25488.1 - 0.0014 18.1 0.2 0.0038 16.7 0.0 1.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.1 ETO25488.1 - 0.0017 19.1 0.4 0.015 16.1 0.0 2.7 2 2 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 ETO25488.1 - 0.0023 17.3 0.0 0.0054 16.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein ResIII PF04851.10 ETO25488.1 - 0.0026 17.6 0.4 0.56 10.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NACHT PF05729.7 ETO25488.1 - 0.0028 17.3 0.0 0.057 13.0 0.0 2.7 2 1 1 3 3 3 1 NACHT domain Zeta_toxin PF06414.7 ETO25488.1 - 0.003 16.6 0.0 0.0063 15.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.17 ETO25488.1 - 0.0041 17.2 0.0 0.014 15.5 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_33 PF13671.1 ETO25488.1 - 0.013 15.4 0.0 0.03 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 ETO25488.1 - 0.013 14.3 0.0 0.025 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 ETO25488.1 - 0.014 14.5 0.0 0.043 12.9 0.0 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 ETO25488.1 - 0.017 13.8 0.0 0.039 12.6 0.0 1.6 1 0 0 1 1 1 0 TIP49 C-terminus AAA_28 PF13521.1 ETO25488.1 - 0.018 15.0 0.1 0.34 10.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 ETO25488.1 - 0.027 14.7 0.1 0.15 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 ETO25488.1 - 0.03 14.0 0.4 2 8.0 0.0 2.9 3 1 1 4 4 4 0 Archaeal ATPase NTPase_1 PF03266.10 ETO25488.1 - 0.033 13.8 0.6 1.6 8.4 0.0 3.0 3 0 0 3 3 3 0 NTPase KaiC PF06745.8 ETO25488.1 - 0.057 12.5 0.0 1.4 7.9 0.0 2.4 2 0 0 2 2 2 0 KaiC ABC_tran PF00005.22 ETO25488.1 - 0.085 13.1 0.0 0.24 11.6 0.0 1.8 1 0 0 1 1 1 0 ABC transporter CDC48_N PF02359.13 ETO25489.1 - 2.2e-16 59.5 0.0 9.3e-16 57.5 0.1 2.0 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain AAA PF00004.24 ETO25489.1 - 9.5e-10 38.7 0.2 2e-09 37.7 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.12 ETO25489.1 - 2.1e-06 27.2 0.0 5.7e-06 25.8 0.0 1.8 1 1 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_17 PF13207.1 ETO25489.1 - 0.0001 23.0 0.2 0.00072 20.3 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 ETO25489.1 - 0.00015 21.4 0.1 0.00035 20.2 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 ETO25489.1 - 0.00033 20.6 0.0 0.00052 20.0 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 ETO25489.1 - 0.00059 19.7 0.1 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 ETO25489.1 - 0.00087 18.4 0.1 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 ETO25489.1 - 0.001 19.2 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 ETO25489.1 - 0.0016 17.2 0.6 0.014 14.1 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus AAA_5 PF07728.9 ETO25489.1 - 0.0029 17.3 0.1 0.0063 16.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 ETO25489.1 - 0.0055 16.1 0.2 0.0092 15.4 0.1 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 ETO25489.1 - 0.0083 16.4 0.1 0.027 14.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 ETO25489.1 - 0.017 14.3 0.1 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI A-2_8-polyST PF07388.6 ETO25489.1 - 0.021 13.2 0.1 0.03 12.6 0.1 1.2 1 0 0 1 1 1 0 Alpha-2,8-polysialyltransferase (POLYST) Zeta_toxin PF06414.7 ETO25489.1 - 0.035 13.1 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.17 ETO25489.1 - 0.056 12.2 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ResIII PF04851.10 ETO25489.1 - 0.057 13.2 0.2 0.11 12.3 0.0 1.6 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit NACHT PF05729.7 ETO25489.1 - 0.059 13.0 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 ETO25489.1 - 0.067 13.3 0.0 0.19 11.8 0.0 1.8 2 0 0 2 2 1 0 RNA helicase PhoH PF02562.11 ETO25489.1 - 0.071 12.3 0.1 0.13 11.4 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.1 ETO25489.1 - 0.072 13.0 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain Menin PF05053.8 ETO25491.1 - 1.5 6.9 12.9 1.9 6.5 9.0 1.2 1 0 0 1 1 1 0 Menin CAP_GLY PF01302.20 ETO25492.1 - 2.6e-23 81.5 6.3 6.9e-18 64.1 0.1 3.1 3 0 0 3 3 3 2 CAP-Gly domain C1_4 PF07975.7 ETO25492.1 - 0.098 12.6 6.5 2.2 8.3 4.6 2.7 3 0 0 3 3 3 0 TFIIH C1-like domain DnaJ_CXXCXGXG PF00684.14 ETO25492.1 - 0.32 11.0 3.8 0.5 10.4 1.9 2.0 2 1 0 2 2 2 0 DnaJ central domain Zn_Tnp_IS1595 PF12760.2 ETO25492.1 - 1 9.2 9.4 0.81 9.5 2.3 2.5 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Apolipo_F PF15148.1 ETO25493.1 - 0.053 12.8 0.2 0.07 12.4 0.1 1.2 1 0 0 1 1 1 0 Apolipoprotein F Serglycin PF04360.7 ETO25495.1 - 0.0032 17.2 0.9 0.0032 17.2 0.6 1.2 1 0 0 1 1 1 1 Serglycin Nop14 PF04147.7 ETO25495.1 - 0.02 12.8 25.2 0.019 12.9 17.5 1.0 1 0 0 1 1 1 0 Nop14-like family TLP-20 PF06088.6 ETO25495.1 - 0.07 12.7 3.7 0.085 12.5 2.5 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Trypan_PARP PF05887.6 ETO25495.1 - 0.14 11.9 16.4 0.18 11.6 11.4 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CENP-T PF15511.1 ETO25495.1 - 0.15 11.3 11.1 0.14 11.3 7.7 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T VID27 PF08553.5 ETO25495.1 - 0.19 9.8 14.4 0.2 9.8 10.0 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein CobT PF06213.7 ETO25495.1 - 0.3 10.1 21.6 0.36 9.9 15.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Prothymosin PF03247.9 ETO25495.1 - 0.59 10.3 36.2 1.1 9.4 25.1 1.5 1 0 0 1 1 1 0 Prothymosin/parathymosin family Tim54 PF11711.3 ETO25495.1 - 0.73 8.3 5.5 0.8 8.2 3.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DDHD PF02862.12 ETO25495.1 - 0.76 9.5 2.6 0.87 9.3 1.8 1.1 1 0 0 1 1 1 0 DDHD domain NOA36 PF06524.7 ETO25495.1 - 0.92 8.6 20.2 1.5 7.9 14.0 1.4 1 0 0 1 1 1 0 NOA36 protein FLO_LFY PF01698.11 ETO25495.1 - 0.95 8.2 7.7 1 8.1 5.4 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Daxx PF03344.10 ETO25495.1 - 1.9 6.8 25.7 2.3 6.5 17.8 1.1 1 0 0 1 1 1 0 Daxx Family TFIIF_alpha PF05793.7 ETO25495.1 - 2.7 6.2 24.2 2.8 6.1 16.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1510 PF07423.6 ETO25495.1 - 4 6.7 19.8 5.1 6.4 13.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) BUD22 PF09073.5 ETO25495.1 - 4.8 6.1 21.6 5.9 5.8 15.0 1.1 1 0 0 1 1 1 0 BUD22 Sigma70_ner PF04546.8 ETO25495.1 - 5 6.6 23.0 8.5 5.9 15.9 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Mannosyl_trans3 PF11051.3 ETO25496.1 - 6.5e-07 28.9 0.2 7.7e-07 28.7 0.1 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative DUF4378 PF14309.1 ETO25497.1 - 0.018 15.1 1.8 0.018 15.1 1.2 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4378) S6PP PF05116.8 ETO25499.1 - 0.016 14.4 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase PSCyt2 PF07583.6 ETO25500.1 - 0.097 12.1 0.2 0.14 11.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1549) PI3Ka PF00613.15 ETO25501.1 - 9e-38 129.2 4.7 1.2e-37 128.9 2.9 1.5 1 1 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 ETO25501.1 - 5.8e-36 124.1 0.3 1.7e-35 122.5 0.2 1.8 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TORC_C PF12886.2 ETO25501.1 - 0.023 14.8 0.4 0.35 11.0 0.0 2.4 2 0 0 2 2 2 0 Transducer of regulated CREB activity, C terminus TLD PF07534.11 ETO25502.1 - 2e-24 86.1 2.7 2e-24 86.1 1.8 2.2 2 1 0 2 2 2 1 TLD ATG2_CAD PF13329.1 ETO25502.1 - 1.4 8.4 9.4 7.1 6.1 4.7 2.2 2 0 0 2 2 2 0 Autophagy-related protein 2 CAD motif NRDE-2 PF08424.5 ETO25502.1 - 2.2 7.0 11.8 1.7 7.4 5.5 2.0 2 0 0 2 2 2 0 NRDE-2, necessary for RNA interference PLRV_ORF5 PF01690.12 ETO25507.1 - 0.88 8.6 18.7 1.2 8.2 13.0 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein PDZ_2 PF13180.1 ETO25508.1 - 0.0032 17.3 0.0 0.0075 16.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 ETO25508.1 - 0.0035 17.4 0.1 0.032 14.4 0.0 2.3 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) Gp-FAR-1 PF05823.7 ETO25509.1 - 0.031 14.2 0.5 0.06 13.2 0.4 1.5 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) EIF_2_alpha PF07541.7 ETO25509.1 - 0.061 13.0 0.4 0.14 11.8 0.3 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit IL7 PF01415.11 ETO25509.1 - 0.063 12.9 5.0 1.5 8.4 0.4 2.5 2 0 0 2 2 2 0 Interleukin 7/9 family PCI_Csn8 PF10075.4 ETO25509.1 - 0.074 12.8 1.3 0.47 10.2 0.2 2.3 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 PTS_IIA PF02255.11 ETO25509.1 - 0.087 12.6 0.3 0.19 11.6 0.2 1.5 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit Exo_endo_phos_2 PF14529.1 ETO25510.1 - 0.0042 16.6 1.3 0.0087 15.6 0.1 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Nucleoplasmin PF03066.10 ETO25510.1 - 3.1 7.3 12.6 6.5 6.2 2.0 2.4 2 0 0 2 2 2 0 Nucleoplasmin DUF4530 PF15039.1 ETO25510.1 - 6.7 6.6 7.2 18 5.2 5.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) Serinc PF03348.10 ETO25514.1 - 0.7 8.5 5.6 1 8.0 3.9 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2615 PF11027.3 ETO25514.1 - 6.5 6.7 5.7 4 7.4 0.1 2.8 2 1 2 4 4 4 0 Protein of unknown function (DUF2615) APC_CDC26 PF10471.4 ETO25515.1 - 0.069 13.8 1.3 0.93 10.2 0.3 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 SR-25 PF10500.4 ETO25515.1 - 9 5.6 10.0 1.4 8.3 3.3 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF676 PF05057.9 ETO25518.1 - 8.1e-29 100.4 0.6 7.2e-27 94.1 0.4 3.0 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 ETO25518.1 - 9e-05 22.1 0.0 0.00021 20.9 0.0 1.7 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 ETO25518.1 - 0.00092 18.9 0.0 0.004 16.9 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETO25518.1 - 0.0016 18.3 0.0 0.0053 16.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family UPF0546 PF10639.4 ETO25519.1 - 0.055 13.2 0.7 0.15 11.9 0.2 1.9 1 1 0 1 1 1 0 Uncharacterised protein family UPF0546 CRCB PF02537.10 ETO25521.1 - 0.002 17.9 14.4 0.0028 17.5 4.7 2.8 3 0 0 3 3 3 2 CrcB-like protein EF-hand_8 PF13833.1 ETO25522.1 - 2.2e-08 33.5 0.1 5.5e-06 25.8 0.0 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 ETO25522.1 - 8.6e-07 27.8 0.3 0.041 13.2 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 ETO25522.1 - 1.1e-06 28.6 0.1 2.1e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO25522.1 - 4e-05 23.1 0.4 0.13 12.2 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 ETO25522.1 - 0.023 14.4 0.1 2.1 8.1 0.0 2.2 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.1 ETO25522.1 - 0.061 12.7 1.3 4.1 6.9 0.1 2.9 3 0 0 3 3 3 0 EF hand RRM_1 PF00076.17 ETO25524.1 - 7.9e-09 35.0 0.0 0.00062 19.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO25524.1 - 2.5e-07 30.5 0.0 0.0051 16.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ORC4_C PF14629.1 ETO25524.1 - 0.073 12.4 2.9 0.12 11.7 0.8 2.0 1 1 1 2 2 2 0 Origin recognition complex (ORC) subunit 4 C-terminus NUDIX PF00293.23 ETO25525.1 - 5.9e-06 25.9 0.0 2.3e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 NUDIX domain 7TM_GPCR_Sri PF10327.4 ETO25526.1 - 0.0014 17.6 0.3 0.0014 17.6 0.2 1.4 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Sri ABC2_membrane_3 PF12698.2 ETO25527.1 - 1.3e-22 80.2 27.4 1.3e-22 80.2 19.0 2.2 2 0 0 2 2 2 1 ABC-2 family transporter protein ABC_tran PF00005.22 ETO25527.1 - 1.5e-20 73.9 0.0 2.6e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_tran PF00005.22 ETO25528.1 - 5e-19 68.9 0.7 4.8e-18 65.7 0.1 2.5 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 ETO25528.1 - 5.9e-10 39.5 0.0 4e-07 30.2 0.0 2.8 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 ETO25528.1 - 0.0063 15.7 0.0 0.27 10.4 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain SRP54 PF00448.17 ETO25528.1 - 0.015 14.7 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain SbcCD_C PF13558.1 ETO25528.1 - 0.023 14.5 0.0 0.1 12.5 0.0 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 ETO25528.1 - 0.025 14.0 0.1 0.066 12.7 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 ETO25528.1 - 0.041 14.2 0.3 0.041 14.2 0.2 1.9 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.2 ETO25529.1 - 1.5e-09 37.4 0.5 2e-09 36.9 0.4 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein Yip1 PF04893.12 ETO25529.1 - 0.078 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Yip1 domain PDR_CDR PF06422.7 ETO25529.1 - 0.46 10.1 4.9 0.23 11.1 1.1 2.1 1 1 1 2 2 2 0 CDR ABC transporter BNR PF02012.15 ETO25529.1 - 1.7 8.7 5.4 0.54 10.2 0.5 2.7 2 0 0 2 2 2 0 BNR/Asp-box repeat Ax_dynein_light PF10211.4 ETO25530.1 - 3.4e-26 92.2 6.3 3.4e-26 92.2 4.3 2.4 2 1 1 3 3 3 1 Axonemal dynein light chain Ribosomal_L36e PF01158.13 ETO25530.1 - 0.11 12.4 2.6 0.19 11.7 0.1 2.6 2 0 0 2 2 2 0 Ribosomal protein L36e Med15 PF09606.5 ETO25531.1 - 0.054 11.6 85.4 0.067 11.3 59.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Arm PF00514.18 ETO25531.1 - 3.9 7.4 7.9 6.5 6.7 0.5 3.1 2 1 0 2 2 2 0 Armadillo/beta-catenin-like repeat PK PF00224.16 ETO25532.1 - 0.0023 16.5 0.4 0.0023 16.5 0.3 1.5 2 0 0 2 2 2 1 Pyruvate kinase, barrel domain YlqD PF11068.3 ETO25533.1 - 1.1 9.2 11.9 2 8.4 7.4 2.0 1 1 0 1 1 1 0 YlqD protein Exonuc_VII_L PF02601.10 ETO25533.1 - 2.7 7.1 9.1 0.43 9.7 3.5 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF2763 PF10961.3 ETO25534.1 - 3.2 8.2 10.6 1.4 9.3 5.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2763) Homeobox PF00046.24 ETO25535.1 - 0.036 13.6 0.7 0.059 13.0 0.5 1.5 1 0 0 1 1 1 0 Homeobox domain FCH PF00611.18 ETO25535.1 - 0.11 12.6 0.8 0.2 11.8 0.6 1.4 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain BRCT PF00533.21 ETO25536.1 - 0.005 16.9 0.1 0.98 9.6 0.0 3.1 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain Corona_nucleoca PF00937.13 ETO25536.1 - 0.9 8.4 18.9 8.5 5.2 14.4 1.6 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein CUB_2 PF02408.15 ETO25538.1 - 0.13 11.8 0.9 0.17 11.4 0.6 1.1 1 0 0 1 1 1 0 CUB-like domain Apc9 PF12856.2 ETO25538.1 - 0.16 12.0 1.0 0.22 11.6 0.7 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 9 HAD PF12710.2 ETO25539.1 - 2.8e-17 63.4 0.2 2.8e-16 60.2 0.2 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 ETO25539.1 - 7.4e-17 62.4 0.0 1.8e-14 54.6 0.0 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 ETO25539.1 - 3.3e-07 29.5 0.0 6.7e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Prothymosin PF03247.9 ETO25539.1 - 0.025 14.7 1.7 0.025 14.7 1.2 4.1 5 0 0 5 5 5 0 Prothymosin/parathymosin family SPARC_Ca_bdg PF10591.4 ETO25539.1 - 0.034 14.1 0.7 0.034 14.1 0.5 2.4 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Hydrolase_3 PF08282.7 ETO25539.1 - 0.042 13.4 0.0 0.042 13.4 0.0 3.9 4 0 0 4 4 4 0 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 ETO25540.1 - 6.4e-39 134.5 3.2 9.2e-39 134.0 2.2 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 ETO25540.1 - 2.6e-21 75.7 0.0 5.8e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 ETO25540.1 - 1e-09 38.8 0.6 2.6e-09 37.5 0.4 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 ETO25540.1 - 0.00057 19.5 4.0 0.00094 18.8 1.6 2.0 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 ETO25541.1 - 5e-06 25.7 2.0 5.9e-06 25.4 0.1 1.9 2 1 0 2 2 2 1 E1-E2 ATPase DUF4231 PF14015.1 ETO25541.1 - 0.068 13.1 0.3 0.68 9.9 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) Tox-GHH PF15636.1 ETO25543.1 - 0.027 14.0 2.8 0.038 13.6 0.3 2.3 2 0 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin DASH_Dad3 PF08656.5 ETO25543.1 - 0.034 13.8 2.6 0.12 12.0 0.1 2.7 3 1 1 4 4 4 0 DASH complex subunit Dad3 DUF2624 PF11116.3 ETO25543.1 - 0.3 11.6 4.2 0.65 10.5 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2624) DUF843 PF05814.6 ETO25544.1 - 0.083 12.6 1.2 0.18 11.6 0.9 1.5 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) PI3_PI4_kinase PF00454.22 ETO25545.1 - 1.6e-19 70.3 0.1 2.2e-19 69.8 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.1 ETO25545.1 - 0.078 11.9 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) GlcNAc PF11397.3 ETO25546.1 - 2.1e-13 50.1 0.6 3.5e-13 49.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase (GlcNAc) DUF3895 PF13034.1 ETO25546.1 - 0.1 12.0 2.3 0.33 10.4 0.0 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3895) GlcNAc PF11397.3 ETO25547.1 - 2.5e-65 220.8 0.5 3.1e-65 220.5 0.3 1.1 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) Pyr_redox_2 PF07992.9 ETO25550.1 - 4.4e-17 62.6 0.0 1.6e-16 60.7 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 ETO25550.1 - 8.1e-17 61.2 0.0 1.4e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 ETO25550.1 - 1.3e-14 54.3 0.0 2.5e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETO25550.1 - 0.00092 19.3 0.0 0.0025 17.8 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase RasGEF PF00617.14 ETO25551.1 - 0.00037 20.2 0.1 0.0006 19.5 0.0 1.4 2 0 0 2 2 2 1 RasGEF domain Sigma70_ECF PF07638.6 ETO25551.1 - 0.1 12.2 0.3 0.13 11.9 0.0 1.3 2 0 0 2 2 2 0 ECF sigma factor YL1 PF05764.8 ETO25553.1 - 3.1e-06 26.9 5.8 3.5e-06 26.8 4.0 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Nucleoplasmin PF03066.10 ETO25553.1 - 4.2e-06 26.3 5.0 4.2e-06 26.3 3.5 1.2 1 0 0 1 1 1 1 Nucleoplasmin Drc1-Sld2 PF11719.3 ETO25553.1 - 0.00092 18.4 4.9 0.00094 18.3 3.4 1.1 1 0 0 1 1 1 1 DNA replication and checkpoint protein Tim54 PF11711.3 ETO25553.1 - 0.0013 17.3 2.7 0.0015 17.2 1.9 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Myc_N PF01056.13 ETO25553.1 - 0.0038 16.4 6.7 0.0045 16.1 4.7 1.1 1 0 0 1 1 1 1 Myc amino-terminal region VID27 PF08553.5 ETO25553.1 - 0.0055 15.0 4.7 0.005 15.1 3.2 1.1 1 0 0 1 1 1 1 VID27 cytoplasmic protein TLP-20 PF06088.6 ETO25553.1 - 0.0078 15.9 2.1 0.011 15.4 1.5 1.3 1 0 0 1 1 1 1 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) GAGA_bind PF06217.7 ETO25553.1 - 0.0078 16.2 3.0 0.0084 16.1 2.1 1.1 1 0 0 1 1 1 1 GAGA binding protein-like family Cnd1_N PF12922.2 ETO25553.1 - 0.016 14.8 0.6 0.023 14.3 0.4 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term eIF3_subunit PF08597.5 ETO25553.1 - 0.017 14.6 14.9 0.025 14.1 10.4 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Ycf1 PF05758.7 ETO25553.1 - 0.029 12.1 4.4 0.033 11.9 3.0 1.2 1 0 0 1 1 1 0 Ycf1 Peptidase_C37 PF05416.7 ETO25553.1 - 0.043 12.1 1.1 0.045 12.0 0.8 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase TFIIF_alpha PF05793.7 ETO25553.1 - 0.047 12.0 18.7 0.071 11.4 13.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DDHD PF02862.12 ETO25553.1 - 0.073 12.8 3.6 0.076 12.7 2.5 1.2 1 0 0 1 1 1 0 DDHD domain DUF2890 PF11081.3 ETO25553.1 - 0.075 13.0 14.8 0.14 12.2 10.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF3381 PF11861.3 ETO25553.1 - 0.079 12.4 17.0 0.13 11.7 11.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Nop53 PF07767.6 ETO25553.1 - 0.085 11.8 16.5 0.13 11.2 11.4 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Cnd2 PF05786.9 ETO25553.1 - 0.13 10.6 12.9 0.21 10.0 8.9 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 Daxx PF03344.10 ETO25553.1 - 0.14 10.6 12.4 0.19 10.2 8.6 1.1 1 0 0 1 1 1 0 Daxx Family Calc_CGRP_IAPP PF00214.14 ETO25553.1 - 0.25 11.3 4.9 0.52 10.3 3.4 1.7 1 1 0 1 1 1 0 Calcitonin / CGRP / IAPP family Merozoite_SPAM PF07133.6 ETO25553.1 - 0.29 11.0 24.5 0.58 10.0 17.0 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Zip PF02535.17 ETO25553.1 - 0.35 9.8 7.7 0.41 9.6 5.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Paf1 PF03985.8 ETO25553.1 - 0.48 9.0 16.0 0.7 8.5 11.1 1.2 1 0 0 1 1 1 0 Paf1 Spore_coat_CotO PF14153.1 ETO25553.1 - 0.55 9.6 15.6 0.9 8.9 10.8 1.3 1 0 0 1 1 1 0 Spore coat protein CotO RNase_H2-Ydr279 PF09468.5 ETO25553.1 - 0.73 8.9 15.0 0.73 8.9 10.4 1.2 1 1 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) PBP1_TM PF14812.1 ETO25553.1 - 0.87 9.9 16.5 0.15 12.3 8.5 1.9 2 0 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Med19 PF10278.4 ETO25553.1 - 0.96 9.0 11.9 1.3 8.6 8.2 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Peptidase_S49_N PF08496.5 ETO25553.1 - 1.4 8.7 11.3 12 5.6 7.5 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF3987 PF13148.1 ETO25553.1 - 1.6 7.2 12.1 2.6 6.4 8.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) TRAP_alpha PF03896.11 ETO25553.1 - 1.9 7.4 10.3 2.5 7.0 7.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.9 ETO25553.1 - 3.2 5.6 14.0 2.9 5.8 8.5 1.7 2 0 0 2 2 2 0 CDC45-like protein RNA_polI_A34 PF08208.6 ETO25553.1 - 3.9 7.1 22.5 5.4 6.6 15.6 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 FAM176 PF14851.1 ETO25553.1 - 4.9 6.8 8.8 6.9 6.3 6.1 1.4 1 0 0 1 1 1 0 FAM176 family Usp PF00582.21 ETO25553.1 - 5.2 7.2 6.0 7.4 6.7 4.1 1.3 1 0 0 1 1 1 0 Universal stress protein family HSP90 PF00183.13 ETO25553.1 - 5.4 5.2 23.3 7.5 4.8 16.2 1.1 1 0 0 1 1 1 0 Hsp90 protein Pox_RNA_Pol_19 PF05320.7 ETO25553.1 - 6.6 6.4 11.7 4.4 7.0 6.9 1.5 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit RR_TM4-6 PF06459.7 ETO25553.1 - 6.7 6.5 16.1 2.1 8.1 9.4 1.4 2 0 0 2 2 1 0 Ryanodine Receptor TM 4-6 YqfQ PF14181.1 ETO25553.1 - 6.7 6.7 19.6 0.75 9.8 10.7 1.5 2 0 0 2 2 1 0 YqfQ-like protein DIM1 PF02966.11 ETO25554.1 - 0.01 15.3 0.2 0.021 14.3 0.1 1.5 1 0 0 1 1 1 0 Mitosis protein DIM1 DUF4482 PF14818.1 ETO25554.1 - 1.9 9.1 6.6 15 6.1 4.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4482) TTL PF03133.10 ETO25555.1 - 6.3e-28 97.5 0.2 3.6e-16 58.9 0.0 2.8 2 1 0 2 2 2 2 Tubulin-tyrosine ligase family SusE PF14292.1 ETO25555.1 - 0.016 15.0 0.1 0.016 15.0 0.0 1.6 2 0 0 2 2 2 0 SusE outer membrane protein Y_Y_Y PF07495.8 ETO25555.1 - 0.044 13.5 0.9 0.27 11.0 0.0 2.3 2 0 0 2 2 2 0 Y_Y_Y domain TMEM107 PF14995.1 ETO25556.1 - 0.067 13.3 1.6 0.17 11.9 1.1 1.7 1 0 0 1 1 1 0 Transmembrane protein Med19 PF10278.4 ETO25558.1 - 0.13 11.8 6.9 0.17 11.5 4.8 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF2413 PF10310.4 ETO25558.1 - 0.19 10.4 11.3 0.24 10.1 7.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) PRP1_N PF06424.7 ETO25558.1 - 0.22 11.8 6.3 0.24 11.6 4.4 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal GSG-1 PF07803.6 ETO25558.1 - 0.53 9.8 2.4 0.53 9.9 1.2 1.3 1 1 0 1 1 1 0 GSG1-like protein Pex16 PF08610.5 ETO25558.1 - 0.62 9.0 7.0 0.74 8.7 4.9 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Ashwin PF15323.1 ETO25558.1 - 0.71 9.8 14.8 0.79 9.6 10.3 1.2 1 0 0 1 1 1 0 Developmental protein Menin PF05053.8 ETO25558.1 - 0.8 7.8 11.1 0.81 7.7 7.7 1.1 1 0 0 1 1 1 0 Menin Neur_chan_memb PF02932.11 ETO25558.1 - 0.81 9.5 8.1 0.91 9.3 5.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region POX PF07526.6 ETO25558.1 - 0.93 9.7 6.3 1.1 9.4 4.4 1.3 1 0 0 1 1 1 0 Associated with HOX TraV PF09676.5 ETO25558.1 - 4.4 8.0 9.1 5.8 7.6 6.3 1.2 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) RP-C_C PF11800.3 ETO25558.1 - 4.5 6.9 7.4 5.5 6.6 5.1 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF3911 PF13050.1 ETO25559.1 - 0.016 15.2 0.6 0.043 13.9 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3911) DUF4377 PF14302.1 ETO25559.1 - 0.024 14.5 1.9 0.032 14.1 0.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4377) Cnd1 PF12717.2 ETO25559.1 - 0.036 13.8 6.1 1.7 8.4 1.2 2.2 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Methyltransf_32 PF13679.1 ETO25560.1 - 0.00033 20.3 4.4 0.00057 19.5 3.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TRM13 PF05206.9 ETO25560.1 - 0.0062 15.8 4.7 0.0091 15.2 1.5 2.1 1 1 1 2 2 2 1 Methyltransferase TRM13 Methyltransf_31 PF13847.1 ETO25560.1 - 0.029 13.9 2.9 0.16 11.5 1.9 2.0 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 ETO25560.1 - 0.065 13.7 0.3 3.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Glyco_tranf_2_4 PF13704.1 ETO25562.1 - 2.6e-09 37.2 1.3 6.2e-09 36.0 0.9 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 TP53IP5 PF15331.1 ETO25563.1 - 0.086 12.7 0.2 0.1 12.5 0.1 1.0 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 UCH PF00443.24 ETO25564.1 - 3.2e-50 170.7 8.8 5.6e-50 169.9 6.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO25564.1 - 6.4e-19 68.5 6.7 1.7e-18 67.1 4.6 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 ETO25564.1 - 0.0003 20.0 2.1 0.0011 18.2 0.0 2.4 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 NNMT_PNMT_TEMT PF01234.12 ETO25564.1 - 0.0025 16.8 0.0 0.0076 15.2 0.0 1.8 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Peptidase_S49_N PF08496.5 ETO25564.1 - 3.3 7.5 6.8 9.2 6.0 4.7 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RNA_pol_Rpc4 PF05132.9 ETO25564.1 - 7.3 6.5 7.5 0.44 10.5 1.4 1.8 2 0 0 2 2 2 0 RNA polymerase III RPC4 UPF0122 PF04297.9 ETO25565.1 - 0.0062 16.5 0.4 0.041 13.8 0.1 2.1 2 0 0 2 2 2 1 Putative helix-turn-helix protein, YlxM / p13 like RTX_C PF08339.5 ETO25565.1 - 0.062 13.0 1.0 0.21 11.2 0.4 2.0 1 1 1 2 2 2 0 RTX C-terminal domain Bap31 PF05529.7 ETO25565.1 - 0.064 12.7 0.2 0.086 12.2 0.1 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like TACC PF05010.9 ETO25565.1 - 0.12 12.1 2.4 1.1 8.9 1.6 1.9 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) Hid1 PF12722.2 ETO25566.1 - 0.0096 13.6 28.2 0.013 13.2 19.5 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein DUF1192 PF06698.6 ETO25566.1 - 0.063 13.0 1.5 0.17 11.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) SlyX PF04102.7 ETO25566.1 - 2.3 8.6 9.9 3.8 7.9 1.1 2.7 2 0 0 2 2 2 0 SlyX BRCT PF00533.21 ETO25567.1 - 0.093 12.8 0.2 0.83 9.8 0.1 2.1 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Diphtheria_T PF02764.9 ETO25567.1 - 0.25 11.1 1.5 0.33 10.7 0.9 1.3 1 1 0 1 1 1 0 Diphtheria toxin, T domain Laps PF10169.4 ETO25567.1 - 0.31 11.2 6.8 0.038 14.2 2.0 1.5 2 0 0 2 2 2 0 Learning-associated protein DUF2514 PF10721.4 ETO25567.1 - 1.1 8.9 6.8 1.5 8.5 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) DNA_pol_B_palm PF14792.1 ETO25568.1 - 0.074 13.1 0.2 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase beta palm Mpp10 PF04006.7 ETO25571.1 - 6.6e-31 107.3 42.6 1.9e-24 86.0 4.5 2.1 2 0 0 2 2 2 2 Mpp10 protein HCV_NS5a_C PF12941.2 ETO25571.1 - 3.6 7.0 7.4 0.81 9.2 0.1 2.2 2 0 0 2 2 2 0 HCV NS5a protein C-terminal region BUD22 PF09073.5 ETO25572.1 - 0.0034 16.5 34.4 0.0045 16.1 23.8 1.1 1 0 0 1 1 1 1 BUD22 Mpp10 PF04006.7 ETO25572.1 - 0.0058 15.0 1.6 0.0058 15.0 1.1 2.1 2 0 0 2 2 2 1 Mpp10 protein DDHD PF02862.12 ETO25572.1 - 1.7 8.4 12.2 0.19 11.4 5.6 1.5 2 0 0 2 2 2 0 DDHD domain TFIIF_alpha PF05793.7 ETO25572.1 - 1.7 6.9 44.4 2.5 6.3 30.7 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CENP-T PF15511.1 ETO25572.1 - 3.4 6.7 15.7 6.3 5.9 10.9 1.5 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Mob1_phocein PF03637.12 ETO25573.1 - 7.2e-58 195.1 0.2 1e-57 194.6 0.2 1.2 1 0 0 1 1 1 1 Mob1/phocein family UCH PF00443.24 ETO25574.1 - 4.2e-12 45.7 0.0 9.2e-12 44.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MRI PF15325.1 ETO25574.1 - 0.00082 20.3 0.1 0.0065 17.4 0.0 2.3 2 0 0 2 2 2 1 Modulator of retrovirus infection WD40 PF00400.27 ETO25575.1 - 3.4e-160 514.9 44.1 1.3e-11 43.9 0.2 16.4 16 0 0 16 16 16 16 WD domain, G-beta repeat NACHT PF05729.7 ETO25575.1 - 7.4e-09 35.4 0.0 1.9e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 NACHT domain DUF1258 PF06869.7 ETO25575.1 - 5.5e-08 32.2 9.1 0.87 8.6 0.0 7.6 3 2 3 9 9 9 4 Protein of unknown function (DUF1258) AAA_18 PF13238.1 ETO25575.1 - 3.1e-07 30.7 0.1 3.1e-07 30.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 ETO25575.1 - 0.0001 22.4 0.0 0.00034 20.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO25575.1 - 0.00015 22.5 0.3 0.00079 20.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Pentapeptide PF00805.17 ETO25575.1 - 0.0099 15.1 2.9 0.041 13.1 0.6 2.1 1 1 1 2 2 2 2 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 ETO25575.1 - 0.048 13.5 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) PD40 PF07676.7 ETO25575.1 - 3.2 7.5 27.6 8.8 6.1 0.0 8.9 10 0 0 10 10 10 0 WD40-like Beta Propeller Repeat DUF3682 PF12446.3 ETO25577.1 - 7.6 6.8 8.4 0.33 11.2 1.3 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3682) OSTbeta PF15048.1 ETO25578.1 - 0.013 15.6 0.9 0.013 15.6 0.6 2.5 1 1 1 2 2 2 0 Organic solute transporter subunit beta protein Selenoprotein_S PF06936.6 ETO25578.1 - 0.016 14.7 0.4 0.016 14.7 0.3 2.1 1 1 1 2 2 2 0 Selenoprotein S (SelS) PDR_CDR PF06422.7 ETO25578.1 - 0.021 14.4 1.5 0.021 14.4 1.0 3.0 1 1 1 2 2 2 0 CDR ABC transporter FixH PF05751.6 ETO25578.1 - 0.029 14.1 2.0 0.066 13.0 0.1 2.1 2 1 0 2 2 2 0 FixH TPR_20 PF14561.1 ETO25578.1 - 0.04 14.0 0.4 0.1 12.7 0.3 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4446 PF14584.1 ETO25578.1 - 0.08 12.7 0.4 0.08 12.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) RIC3 PF15361.1 ETO25578.1 - 0.26 11.5 12.4 0.097 12.9 0.4 2.3 1 1 1 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 OATP PF03137.15 ETO25578.1 - 0.73 7.8 7.8 2.6 6.0 0.2 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Gastrin PF00918.12 ETO25578.1 - 0.78 10.5 9.0 0.31 11.8 0.4 2.2 2 0 0 2 2 2 0 Gastrin/cholecystokinin family Zip PF02535.17 ETO25578.1 - 2.4 7.1 5.4 0.64 8.9 1.4 1.7 1 1 1 2 2 2 0 ZIP Zinc transporter Ctr PF04145.10 ETO25578.1 - 3.5 7.6 12.0 0.048 13.7 1.0 2.2 1 1 1 2 2 2 0 Ctr copper transporter family DUF2615 PF11027.3 ETO25578.1 - 5.3 7.0 7.7 3.1 7.7 1.2 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) Serinc PF03348.10 ETO25578.1 - 6.8 5.2 14.3 1.2 7.7 1.3 2.0 1 1 1 2 2 2 0 Serine incorporator (Serinc) CAP_GLY PF01302.20 ETO25579.1 - 1.9e-15 56.3 1.3 3.3e-15 55.5 0.9 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF3367 PF11847.3 ETO25579.1 - 0.062 11.2 3.9 0.077 10.9 2.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) DUF2012 PF09430.5 ETO25580.1 - 3.6e-06 26.8 0.2 0.00014 21.6 0.1 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF2012) DUF4149 PF13664.1 ETO25580.1 - 0.084 12.9 1.2 0.097 12.7 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) WD40 PF00400.27 ETO25582.1 - 2.9e-09 36.4 3.2 0.0022 17.8 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat CorA PF01544.13 ETO25583.1 - 8.4e-32 110.3 0.0 1.3e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein AlphaC_N PF08829.5 ETO25583.1 - 0.028 13.7 0.1 0.17 11.1 0.0 2.1 2 0 0 2 2 2 0 Alpha C protein N terminal DUF2517 PF10725.4 ETO25583.1 - 0.074 12.7 0.3 13 5.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2517) NUDIX PF00293.23 ETO25584.1 - 8.8e-16 57.7 0.0 1.4e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Nudix_N_2 PF14803.1 ETO25584.1 - 2.3e-07 30.3 0.7 8.8e-07 28.5 0.0 2.3 2 0 0 2 2 2 1 Nudix N-terminal DUF2757 PF10955.3 ETO25584.1 - 0.08 13.1 1.5 5.6 7.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2757) DUF2875 PF11394.3 ETO25586.1 - 3.6 6.0 6.9 4.2 5.8 4.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2875) Neugrin PF06413.6 ETO25588.1 - 0.15 11.9 6.5 0.38 10.5 4.5 1.6 1 0 0 1 1 1 0 Neugrin L31 PF09784.4 ETO25588.1 - 0.24 11.4 0.1 0.24 11.4 0.1 3.5 4 0 0 4 4 4 0 Mitochondrial ribosomal protein L31 SAM_2 PF07647.12 ETO25589.1 - 0.034 13.9 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Ras PF00071.17 ETO25590.1 - 1.5e-12 47.2 0.2 3.9e-06 26.3 0.0 2.3 2 1 0 2 2 2 2 Ras family GTP_EFTU PF00009.22 ETO25590.1 - 0.092 12.1 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain HEAT PF02985.17 ETO25591.1 - 0.00037 20.3 3.2 0.55 10.4 0.0 3.8 4 0 0 4 4 4 2 HEAT repeat TIP120 PF08623.5 ETO25591.1 - 0.0028 17.2 2.5 0.0042 16.6 0.7 2.0 1 1 2 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 ETO25591.1 - 0.0077 16.4 0.0 0.023 14.9 0.0 1.9 1 1 1 2 2 2 1 HEAT repeats CLASP_N PF12348.3 ETO25591.1 - 0.014 14.8 0.1 0.024 13.9 0.1 1.3 1 0 0 1 1 1 0 CLASP N terminal Atx10homo_assoc PF09759.4 ETO25591.1 - 0.034 13.8 0.1 0.071 12.8 0.1 1.6 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain EF_TS PF00889.14 ETO25593.1 - 6.7e-41 140.0 0.3 1.1e-40 139.2 0.2 1.4 1 0 0 1 1 1 1 Elongation factor TS DUF1120 PF06551.7 ETO25593.1 - 0.02 15.2 0.0 0.063 13.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1120) Ish1 PF10281.4 ETO25593.1 - 0.068 13.2 0.2 0.44 10.6 0.0 2.6 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein DUF1162 PF06650.7 ETO25595.1 - 0.004 16.4 0.1 0.011 14.9 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1162) Kelch_6 PF13964.1 ETO25597.1 - 1.9e-06 27.7 11.3 0.011 15.8 0.2 5.5 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.20 ETO25597.1 - 0.00027 20.4 16.1 0.0022 17.4 0.4 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 ETO25597.1 - 0.0034 17.3 4.8 0.0073 16.2 0.3 3.5 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.1 ETO25597.1 - 0.013 15.2 1.5 1 9.1 0.0 3.4 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO25597.1 - 0.028 14.6 0.2 0.38 10.9 0.0 3.0 5 0 0 5 5 5 0 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO25597.1 - 0.047 13.4 10.5 0.33 10.7 0.7 5.3 6 1 0 6 6 6 0 Kelch motif Neur_chan_memb PF02932.11 ETO25598.1 - 0.023 14.5 1.0 0.034 14.0 0.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Secretin_N_2 PF07655.8 ETO25598.1 - 0.24 11.7 17.0 0.59 10.5 11.8 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain Cytochrome_CBB3 PF13442.1 ETO25599.1 - 0.085 13.0 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III Glycos_transf_1 PF00534.15 ETO25600.1 - 5.8e-26 90.9 0.0 1e-25 90.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 ETO25600.1 - 2.3e-09 37.5 0.0 3.4e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Neur_chan_memb PF02932.11 ETO25601.1 - 0.0048 16.8 1.2 0.0068 16.3 0.9 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region G10 PF01125.12 ETO25601.1 - 0.56 9.7 3.6 0.32 10.5 0.4 1.9 2 0 0 2 2 2 0 G10 protein SR-25 PF10500.4 ETO25603.1 - 4.3 6.7 11.0 0.11 11.9 0.7 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SNF2_N PF00176.18 ETO25604.1 - 0.00047 19.0 0.0 0.0009 18.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SNF2_N PF00176.18 ETO25605.1 - 1.3e-21 76.7 0.2 1.6e-21 76.3 0.1 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain NinB PF05772.7 ETO25605.1 - 0.2 11.2 3.6 0.17 11.5 1.2 1.7 1 1 1 2 2 2 0 NinB protein DUF3622 PF12286.3 ETO25607.1 - 0.058 13.7 0.1 0.096 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3622) zf-U1 PF06220.7 ETO25609.1 - 0.66 9.5 3.7 1.5 8.3 0.1 2.4 2 0 0 2 2 2 0 U1 zinc finger DUF373 PF04123.8 ETO25610.1 - 0.0085 15.1 3.9 0.037 13.0 2.3 1.9 1 1 1 2 2 2 2 Domain of unknown function (DUF373) Mito_carr PF00153.22 ETO25611.1 - 6.3e-29 99.5 0.0 3.9e-15 55.3 0.1 2.3 1 1 1 2 2 2 2 Mitochondrial carrier protein PH PF00169.24 ETO25612.1 - 0.018 15.2 0.1 0.05 13.8 0.1 1.8 1 0 0 1 1 1 0 PH domain Glyco_transf_41 PF13844.1 ETO25612.1 - 0.5 8.2 3.2 0.86 7.5 2.2 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 41 Sporozoite_P67 PF05642.6 ETO25612.1 - 0.93 7.2 15.3 0.014 13.2 5.3 1.7 2 0 0 2 2 2 0 Sporozoite P67 surface antigen OppC_N PF12911.2 ETO25613.1 - 0.045 13.1 0.2 0.1 11.9 0.1 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Baculo_11_kDa PF06143.6 ETO25613.1 - 0.046 13.0 0.6 0.096 12.0 0.4 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family EphA2_TM PF14575.1 ETO25613.1 - 0.062 13.6 0.2 0.16 12.4 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain P12 PF12669.2 ETO25613.1 - 0.068 13.3 0.7 0.13 12.4 0.5 1.5 1 0 0 1 1 1 0 Virus attachment protein p12 family Secretin_N_2 PF07655.8 ETO25613.1 - 0.14 12.5 19.8 0.22 11.9 13.7 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain DUF3139 PF11337.3 ETO25613.1 - 0.17 12.2 3.0 0.3 11.3 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) DUF566 PF04484.7 ETO25613.1 - 0.42 10.0 10.4 0.62 9.5 7.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Tetraspannin PF00335.15 ETO25613.1 - 1.6 7.9 5.6 0.52 9.5 0.1 2.1 2 0 0 2 2 2 0 Tetraspanin family Macoilin PF09726.4 ETO25613.1 - 1.7 6.8 6.6 2.2 6.4 4.6 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF2500 PF10694.4 ETO25613.1 - 7.3 6.6 6.0 1 9.3 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) CH PF00307.26 ETO25614.1 - 0.004 17.1 0.2 0.004 17.1 0.2 1.7 2 0 0 2 2 2 1 Calponin homology (CH) domain SWIB PF02201.13 ETO25614.1 - 0.0068 16.0 0.0 0.017 14.8 0.0 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain YkyA PF10368.4 ETO25614.1 - 5 6.4 10.6 81 2.4 6.4 2.7 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein NST1 PF13945.1 ETO25615.1 - 0.017 15.1 4.3 0.033 14.2 3.0 1.5 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF420 PF04238.7 ETO25615.1 - 0.64 9.9 6.4 0.21 11.5 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF420) DSPc PF00782.15 ETO25617.1 - 4.6e-20 71.5 0.9 1.2e-19 70.2 0.1 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 ETO25617.1 - 2.9e-05 23.5 0.0 6.5e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF3764 PF12594.3 ETO25617.1 - 0.063 13.0 0.3 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3764) NAD_binding_1 PF00175.16 ETO25618.1 - 2.4e-24 86.0 0.0 4.9e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 ETO25618.1 - 4.9e-07 29.7 0.0 1.7e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 Ferric reductase NAD binding domain DHHA1 PF02272.14 ETO25619.1 - 0.013 15.1 0.0 0.027 14.1 0.0 1.6 1 0 0 1 1 1 0 DHHA1 domain GlgS PF08971.6 ETO25619.1 - 0.12 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Glycogen synthesis protein HTH_Crp_2 PF13545.1 ETO25620.1 - 0.0075 16.0 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain RuvB_C PF05491.8 ETO25620.1 - 0.035 13.7 0.0 0.074 12.6 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB C-terminus Glyco_hydro_31 PF01055.21 ETO25621.1 - 2.2e-12 46.5 1.2 3.5e-12 45.9 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Glyco_hydro_31 PF01055.21 ETO25622.1 - 1.8e-08 33.6 0.3 3.4e-08 32.7 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4199 PF13858.1 ETO25622.1 - 0.32 10.9 0.0 0.32 10.9 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) Glyco_hydro_31 PF01055.21 ETO25623.1 - 7.5e-14 51.4 0.2 1.3e-13 50.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF727 PF05303.7 ETO25623.1 - 0.036 13.8 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF727) WD40 PF00400.27 ETO25624.1 - 3.1e-94 305.8 35.4 1e-11 44.1 0.7 11.2 11 0 0 11 11 11 10 WD domain, G-beta repeat Nup160 PF11715.3 ETO25624.1 - 1.9e-14 52.7 10.2 0.0017 16.6 0.0 7.3 4 2 3 7 7 7 7 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO25624.1 - 6.1e-06 25.2 25.4 1.1 7.8 0.5 7.1 4 2 3 8 8 8 6 Nup133 N terminal like Treslin_N PF15292.1 ETO25626.1 - 0.00085 17.3 5.7 0.00088 17.2 4.0 1.1 1 0 0 1 1 1 1 Treslin N-terminus DUF2201_N PF13203.1 ETO25626.1 - 0.16 11.0 11.0 0.18 10.9 7.6 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain BSMAP PF12280.3 ETO25626.1 - 0.37 10.6 6.8 0.43 10.4 4.7 1.2 1 0 0 1 1 1 0 Brain specific membrane anchored protein Kei1 PF08552.6 ETO25626.1 - 1.1 8.9 8.7 1.7 8.2 6.1 1.4 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF4220 PF13968.1 ETO25626.1 - 1.6 7.7 5.3 1.9 7.5 3.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Hid1 PF12722.2 ETO25626.1 - 1.6 6.3 10.7 1.8 6.1 7.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Asp-B-Hydro_N PF05279.6 ETO25626.1 - 1.6 8.5 15.2 1.8 8.3 10.6 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CDC45 PF02724.9 ETO25626.1 - 1.6 6.6 13.9 1.9 6.4 9.6 1.0 1 0 0 1 1 1 0 CDC45-like protein MRP-S32 PF10210.4 ETO25626.1 - 2.2 8.6 10.1 2.8 8.3 6.5 1.4 1 1 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 eIF3_subunit PF08597.5 ETO25626.1 - 2.7 7.4 21.6 3.3 7.1 15.0 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF2422 PF10337.4 ETO25626.1 - 3.1 6.5 5.4 3.3 6.3 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) DDHD PF02862.12 ETO25626.1 - 3.4 7.3 9.0 4.2 7.1 6.2 1.1 1 0 0 1 1 1 0 DDHD domain HSP70 PF00012.15 ETO25626.1 - 3.7 5.3 12.3 4.2 5.1 8.5 1.0 1 0 0 1 1 1 0 Hsp70 protein Spore_coat_CotO PF14153.1 ETO25626.1 - 5.1 6.5 21.9 6.4 6.1 15.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Neur_chan_memb PF02932.11 ETO25626.1 - 5.7 6.7 7.2 6.6 6.5 5.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FHIPEP PF00771.15 ETO25626.1 - 8.5 4.5 6.2 11 4.2 4.3 1.1 1 0 0 1 1 1 0 FHIPEP family DUF853 PF05872.7 ETO25626.1 - 8.8 4.5 7.3 10 4.3 5.0 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Myotub-related PF06602.9 ETO25627.1 - 1.4e-122 408.8 0.8 2.6e-122 408.0 0.5 1.4 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain 3-PAP PF12578.3 ETO25627.1 - 0.00036 20.3 0.7 0.0011 18.8 0.2 2.1 2 0 0 2 2 2 1 Myotubularin-associated protein DSPc PF00782.15 ETO25627.1 - 0.00088 18.8 1.8 0.0011 18.5 0.1 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 ETO25627.1 - 0.00099 18.5 0.1 0.0028 17.0 0.1 1.7 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 ETO25627.1 - 0.0033 17.7 0.7 0.0087 16.3 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family GRAM PF02893.15 ETO25627.1 - 0.024 14.1 0.0 0.073 12.6 0.0 1.8 1 0 0 1 1 1 0 GRAM domain Nop PF01798.13 ETO25628.1 - 3.7e-55 185.3 0.1 3.7e-55 185.3 0.0 2.2 2 0 0 2 2 2 1 Putative snoRNA binding domain Phage_30_8 PF06019.6 ETO25628.1 - 0.79 9.4 0.0 0.79 9.4 0.0 2.3 2 0 0 2 2 2 0 Phage GP30.8 protein RINT1_TIP1 PF04437.8 ETO25629.1 - 0.00065 18.3 3.0 0.0012 17.5 2.1 1.5 1 1 0 1 1 1 1 RINT-1 / TIP-1 family SRP_SPB PF02978.14 ETO25629.1 - 0.13 12.5 0.8 1.1 9.5 0.2 2.6 3 1 0 3 3 3 0 Signal peptide binding domain Vps53_N PF04100.7 ETO25630.1 - 3.2e-34 118.3 10.7 3.4e-34 118.2 7.4 1.0 1 0 0 1 1 1 1 Vps53-like, N-terminal Baculo_PEP_C PF04513.7 ETO25630.1 - 0.025 14.4 0.4 0.054 13.3 0.1 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1759 PF03564.10 ETO25630.1 - 0.043 13.6 6.5 1.5 8.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) DUF2854 PF11016.3 ETO25630.1 - 0.16 11.5 0.1 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2854) DUF3782 PF12644.2 ETO25630.1 - 0.37 10.6 4.3 0.37 10.6 1.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3782) Peptidase_U57 PF05582.7 ETO25630.1 - 0.73 8.7 5.6 1 8.3 3.9 1.2 1 0 0 1 1 1 0 YabG peptidase U57 Cas_DxTHG PF09455.5 ETO25630.1 - 1.2 8.2 9.6 1.5 7.9 6.7 1.1 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family V_ATPase_I PF01496.14 ETO25630.1 - 3.2 5.5 7.6 2.2 6.0 4.2 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4617 PF15395.1 ETO25630.1 - 3.6 5.5 17.5 4.2 5.2 12.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4617) YlbD_coat PF14071.1 ETO25630.1 - 3.8 7.5 10.9 19 5.3 4.6 2.7 1 1 2 3 3 3 0 Putative coat protein SR-25 PF10500.4 ETO25630.1 - 7.2 6.0 18.8 10 5.5 13.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Vps53_N PF04100.7 ETO25631.1 - 1.9e-29 102.6 1.7 2.5e-29 102.2 1.2 1.1 1 0 0 1 1 1 1 Vps53-like, N-terminal Zip PF02535.17 ETO25633.1 - 0.06 12.3 0.6 0.18 10.8 0.4 1.7 1 0 0 1 1 1 0 ZIP Zinc transporter WD40 PF00400.27 ETO25634.1 - 9.3e-75 244.0 19.0 8.4e-12 44.4 0.0 7.0 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO25634.1 - 2.2e-10 40.5 1.2 0.0011 18.7 0.1 3.2 1 1 4 5 5 5 5 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO25634.1 - 1.4e-08 33.3 4.7 0.0036 15.5 0.3 4.0 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO25634.1 - 6.2e-05 21.4 0.7 0.0013 17.0 0.1 2.4 3 0 0 3 3 3 1 Cytochrome D1 heme domain PD40 PF07676.7 ETO25634.1 - 0.0003 20.3 7.2 1.2 8.8 0.1 5.0 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Phage_CI_repr PF07022.8 ETO25634.1 - 0.007 16.4 0.1 1.2 9.2 0.0 3.2 3 0 0 3 3 3 1 Bacteriophage CI repressor helix-turn-helix domain PQQ_2 PF13360.1 ETO25634.1 - 0.073 12.5 0.3 0.65 9.4 0.2 2.6 1 1 1 2 2 2 0 PQQ-like domain GATase PF00117.23 ETO25634.1 - 0.081 12.3 0.0 0.84 9.0 0.0 2.5 2 1 1 3 3 3 0 Glutamine amidotransferase class-I DUF1258 PF06869.7 ETO25634.1 - 0.085 11.9 1.9 7.4 5.5 0.0 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF1258) DUF281 PF03436.8 ETO25634.1 - 0.22 11.6 1.6 6.4 6.9 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF281) TFIIIC_delta PF12657.2 ETO25634.1 - 0.31 10.7 2.1 0.63 9.7 0.1 2.4 3 0 0 3 3 3 0 Transcription factor IIIC subunit delta N-term Kinesin PF00225.18 ETO25635.1 - 7.7e-33 113.5 0.1 1.1e-32 113.1 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain GatB_Yqey PF02637.13 ETO25635.1 - 0.0019 17.9 0.4 0.31 10.7 0.0 2.1 2 0 0 2 2 2 2 GatB domain DUF1192 PF06698.6 ETO25635.1 - 0.026 14.3 0.1 0.05 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Cep57_MT_bd PF06657.8 ETO25635.1 - 0.029 14.3 0.6 1.1 9.2 0.2 2.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF3573 PF12097.3 ETO25635.1 - 0.058 11.9 0.9 0.066 11.8 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Prefoldin PF02996.12 ETO25635.1 - 0.23 11.1 3.7 0.27 10.9 1.4 1.9 2 1 0 2 2 2 0 Prefoldin subunit DUF720 PF05302.6 ETO25636.1 - 0.011 15.5 0.2 0.011 15.5 0.2 3.1 3 1 0 4 4 4 0 Protein of unknown function (DUF720) DUF904 PF06005.7 ETO25636.1 - 0.014 15.6 8.4 0.014 15.6 5.8 4.8 4 2 2 6 6 6 0 Protein of unknown function (DUF904) Reo_sigmaC PF04582.7 ETO25636.1 - 0.069 12.3 1.1 0.12 11.5 0.7 1.6 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF2937 PF11157.3 ETO25636.1 - 1 8.7 4.6 3.2 7.0 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) NPV_P10 PF05531.7 ETO25636.1 - 1.2 9.3 14.3 0.15 12.3 1.1 3.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein WXG100 PF06013.7 ETO25636.1 - 1.9 8.5 11.9 0.84 9.6 3.1 3.7 2 1 1 3 3 3 0 Proteins of 100 residues with WXG DUF641 PF04859.7 ETO25636.1 - 7.8 6.2 36.3 0.54 10.0 5.8 4.5 2 2 2 4 4 4 0 Plant protein of unknown function (DUF641) WD40 PF00400.27 ETO25637.1 - 3.5e-07 29.8 0.2 0.017 14.9 0.0 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat TPR_11 PF13414.1 ETO25637.1 - 2.4e-06 27.1 6.9 2.6e-05 23.7 1.1 2.1 1 1 1 2 2 2 2 TPR repeat TPR_16 PF13432.1 ETO25637.1 - 9.8e-06 26.1 0.0 1.7e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO25637.1 - 3.5e-05 23.2 4.5 0.016 14.7 0.2 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO25637.1 - 0.00024 20.7 0.4 0.26 11.3 0.0 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO25637.1 - 0.016 15.5 0.0 0.069 13.4 0.0 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat Gti1_Pac2 PF09729.4 ETO25637.1 - 0.37 10.6 11.4 0.19 11.5 1.9 2.3 2 0 0 2 2 2 0 Gti1/Pac2 family RRP7 PF12923.2 ETO25637.1 - 3.9 7.4 12.1 0.079 12.9 2.0 2.2 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) Kelch_1 PF01344.20 ETO25638.1 - 7.3e-08 31.8 0.9 0.0042 16.6 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO25638.1 - 3.9e-07 29.9 9.2 0.015 15.4 0.0 5.4 5 1 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 ETO25638.1 - 7.9e-06 25.8 2.2 0.00046 20.2 0.0 3.8 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO25638.1 - 0.00074 19.1 0.0 0.53 10.1 0.0 4.3 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 ETO25638.1 - 0.15 12.0 11.1 14 5.7 0.0 4.7 4 0 0 4 4 4 0 Kelch motif Chlam_PMP PF02415.12 ETO25638.1 - 2.2 8.7 40.7 1.1 9.7 0.0 9.6 11 0 0 11 11 11 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Peptidase_C14 PF00656.17 ETO25639.1 - 1.1e-12 48.2 0.2 1.5e-12 47.7 0.2 1.2 1 0 0 1 1 1 1 Caspase domain Kelch_6 PF13964.1 ETO25640.1 - 6.1e-05 23.0 2.8 1.8 8.8 0.1 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO25640.1 - 0.0039 16.7 9.9 0.35 10.4 0.1 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 ETO25640.1 - 0.013 15.4 3.0 4 7.4 0.2 4.3 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.10 ETO25640.1 - 0.028 14.1 0.7 10 6.0 0.1 4.0 4 0 0 4 4 4 0 Kelch motif MRP-S26 PF14943.1 ETO25640.1 - 0.035 13.6 9.4 0.026 14.0 4.5 2.0 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 WD40 PF00400.27 ETO25641.1 - 1.3e-75 246.8 20.1 1.6e-13 49.9 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO25641.1 - 4.7e-11 41.5 5.7 0.026 12.6 0.0 5.3 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Kelch_4 PF13418.1 ETO25641.1 - 1.6e-05 24.5 0.4 0.0089 15.7 0.0 4.1 2 1 1 3 3 3 1 Galactose oxidase, central domain Cytochrom_D1 PF02239.11 ETO25641.1 - 0.00012 20.5 2.3 0.064 11.5 0.1 3.3 1 1 3 4 4 4 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO25641.1 - 0.00029 20.3 0.2 0.0019 17.7 0.1 2.4 1 1 0 1 1 1 1 PQQ-like domain PD40 PF07676.7 ETO25641.1 - 0.00036 20.1 1.8 8.7 6.1 0.0 5.2 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO25641.1 - 0.00042 19.1 16.9 2.3 6.8 5.9 6.1 1 1 4 5 5 5 2 Nup133 N terminal like Kelch_6 PF13964.1 ETO25641.1 - 0.0015 18.5 0.2 0.0015 18.5 0.2 4.4 5 0 0 5 5 5 1 Kelch motif Proteasome_A_N PF10584.4 ETO25641.1 - 0.0041 16.3 4.8 2 7.8 0.0 4.2 4 0 0 4 4 4 1 Proteasome subunit A N-terminal signature Kelch_2 PF07646.10 ETO25641.1 - 0.01 15.5 2.3 0.033 13.9 0.1 3.0 3 0 0 3 3 3 0 Kelch motif Nbas_N PF15492.1 ETO25641.1 - 0.012 14.7 0.9 1.7 7.7 0.1 3.3 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Kelch_5 PF13854.1 ETO25641.1 - 0.017 15.0 1.1 0.017 15.0 0.7 3.1 3 0 0 3 3 3 0 Kelch motif Kelch_1 PF01344.20 ETO25641.1 - 0.057 12.9 2.5 0.21 11.1 0.3 2.5 2 0 0 2 2 2 0 Kelch motif F420_ligase PF01996.11 ETO25641.1 - 0.079 12.0 0.0 3.5 6.6 0.0 2.4 2 0 0 2 2 2 0 F420-0:Gamma-glutamyl ligase TFIIIC_delta PF12657.2 ETO25641.1 - 2.2 7.9 6.6 0.53 9.9 0.3 2.9 4 1 0 4 4 4 0 Transcription factor IIIC subunit delta N-term PH PF00169.24 ETO25642.1 - 5.2e-07 29.8 0.3 5.2e-07 29.8 0.2 2.6 2 1 0 2 2 2 1 PH domain PH_8 PF15409.1 ETO25642.1 - 0.0002 21.3 0.4 0.00078 19.4 0.2 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.1 ETO25642.1 - 0.0028 17.6 0.1 0.0028 17.6 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Med27 PF11571.3 ETO25642.1 - 0.09 12.9 4.6 1.6 8.9 0.1 3.6 3 0 0 3 3 3 0 Mediator complex subunit 27 DUF106 PF01956.11 ETO25642.1 - 0.41 10.1 4.8 0.32 10.5 0.9 2.4 2 0 0 2 2 2 0 Integral membrane protein DUF106 Fungal_trans_2 PF11951.3 ETO25642.1 - 2.2 6.8 7.9 2.1 6.8 4.3 1.8 1 1 0 1 1 1 0 Fungal specific transcription factor domain FAD-SLDH PF12318.3 ETO25642.1 - 4 7.1 8.3 1.2 8.8 3.1 2.0 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase BBP1_C PF15272.1 ETO25642.1 - 4.2 6.8 27.1 0.29 10.6 14.2 2.4 2 1 0 2 2 2 0 Spindle pole body component BBP1, C-terminal Reticulon PF02453.12 ETO25643.1 - 3.6e-05 23.4 1.2 6.5e-05 22.5 0.8 1.4 1 0 0 1 1 1 1 Reticulon Gal-bind_lectin PF00337.17 ETO25643.1 - 0.0031 16.8 0.0 0.0041 16.4 0.0 1.3 1 1 0 1 1 1 1 Galactoside-binding lectin DUF2207 PF09972.4 ETO25643.1 - 0.0067 15.0 5.6 0.0081 14.7 3.9 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Pox_A_type_inc PF04508.7 ETO25643.1 - 0.014 15.1 0.3 0.41 10.5 0.0 3.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF948 PF06103.6 ETO25643.1 - 0.027 14.3 3.4 2.6 7.9 0.0 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) tRNA_lig_CPD PF08302.6 ETO25643.1 - 0.071 12.3 5.4 0.12 11.6 3.7 1.2 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain SBDS_C PF09377.5 ETO25643.1 - 1 9.0 7.1 0.48 10.1 1.9 2.2 2 0 0 2 2 2 0 SBDS protein C-terminal domain FlaC_arch PF05377.6 ETO25643.1 - 8.6 6.3 9.8 5.2 7.0 0.8 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF1637 PF07847.7 ETO25644.1 - 2.1e-19 69.6 4.0 8.4e-19 67.7 2.8 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1637) YHYH PF14240.1 ETO25644.1 - 0.041 13.5 1.3 0.071 12.7 0.3 1.7 1 1 0 1 1 1 0 YHYH protein DUF1767 PF08585.7 ETO25644.1 - 0.049 13.8 0.2 0.087 13.0 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1767) RabGAP-TBC PF00566.13 ETO25645.1 - 7e-11 42.0 0.3 7e-11 42.0 0.2 3.7 4 1 0 4 4 4 1 Rab-GTPase-TBC domain Striatin PF08232.7 ETO25645.1 - 1.3 9.3 25.8 0.39 11.0 6.1 3.1 2 1 0 2 2 2 0 Striatin family UPF0104 PF03706.8 ETO25645.1 - 4.2 6.5 10.6 0.36 10.0 3.3 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0104) Peptidase_M22 PF00814.20 ETO25646.1 - 8e-74 248.4 0.2 1.8e-73 247.3 0.1 1.5 1 1 0 1 1 1 1 Glycoprotease family CmcH_NodU PF02543.10 ETO25646.1 - 0.022 13.8 0.1 0.033 13.3 0.1 1.2 1 0 0 1 1 1 0 Carbamoyltransferase Galactosyl_T PF01762.16 ETO25647.1 - 2e-08 34.0 3.3 4.5e-08 32.9 2.3 1.6 1 1 0 1 1 1 1 Galactosyltransferase DUF1940 PF09155.5 ETO25647.1 - 0.046 13.5 0.2 0.078 12.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) MIF4G PF02854.14 ETO25649.1 - 1.2e-21 77.0 6.2 2.2e-19 69.6 1.9 3.3 2 1 0 2 2 2 2 MIF4G domain MA3 PF02847.12 ETO25649.1 - 0.024 14.3 0.4 0.49 10.1 0.0 3.1 3 0 0 3 3 3 0 MA3 domain Kazal_1 PF00050.16 ETO25650.1 - 0.11 12.5 0.8 0.24 11.4 0.6 1.6 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain fn3 PF00041.16 ETO25651.1 - 0.00032 20.7 0.0 0.00075 19.5 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain UPF0184 PF03670.8 ETO25652.1 - 2.1 8.5 4.8 2.4 8.4 2.7 1.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) PH PF00169.24 ETO25653.1 - 6.5e-11 42.3 2.5 1.2e-10 41.5 1.7 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 ETO25653.1 - 5.6e-07 29.7 2.6 5.6e-07 29.7 1.8 2.1 2 1 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.1 ETO25653.1 - 0.001 19.1 0.0 0.0031 17.5 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Mcp5_PH PF12814.2 ETO25653.1 - 0.0027 17.6 4.8 0.0028 17.5 2.3 1.8 1 1 1 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology PH_8 PF15409.1 ETO25653.1 - 0.0029 17.6 2.2 0.022 14.8 1.5 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain S_tail_recep_bd PF14928.1 ETO25653.1 - 0.065 13.4 0.0 0.16 12.1 0.0 1.5 1 1 0 1 1 1 0 Short tail fibre protein receptor-binding domain PMAIP1 PF15150.1 ETO25653.1 - 0.071 12.8 0.2 0.071 12.8 0.1 1.9 2 0 0 2 2 2 0 Phorbol-12-myristate-13-acetate-induced PH_4 PF15404.1 ETO25653.1 - 5.1 6.5 10.3 0.046 13.2 0.5 2.2 3 0 0 3 3 3 0 Pleckstrin homology domain Sigma70_ner PF04546.8 ETO25654.1 - 1.9 8.0 7.9 2.8 7.5 5.5 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.4 ETO25654.1 - 6.2 5.4 15.4 8.5 4.9 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF4559 PF15112.1 ETO25656.1 - 0.0073 15.5 7.7 0.0089 15.2 5.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4559) Histone PF00125.19 ETO25656.1 - 0.089 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 AAA_23 PF13476.1 ETO25656.1 - 0.13 12.6 14.8 0.14 12.4 10.2 1.0 1 0 0 1 1 1 0 AAA domain Chordopox_L2 PF05803.7 ETO25656.1 - 2.5 7.7 9.8 0.24 11.0 0.6 2.9 2 1 1 3 3 3 0 Chordopoxvirus L2 protein DUF972 PF06156.8 ETO25656.1 - 3.6 7.9 9.0 3.1 8.1 5.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF2868 PF11067.3 ETO25657.1 - 0.09 11.8 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) FAM163 PF15069.1 ETO25657.1 - 0.2 12.1 2.1 0.26 11.8 0.9 1.6 1 1 1 2 2 2 0 FAM163 family Shisa PF13908.1 ETO25657.1 - 0.31 11.1 8.4 0.017 15.3 1.6 1.8 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator RCR PF12273.3 ETO25657.1 - 0.86 10.1 13.2 1.8 9.1 9.1 1.6 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Ice_nucleation PF00818.12 ETO25657.1 - 1.1 8.7 5.1 0.74 9.2 2.0 1.9 2 0 0 2 2 2 0 Ice nucleation protein repeat Ebola_NP PF05505.7 ETO25657.1 - 7.1 4.5 9.0 9 4.2 6.3 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein rve PF00665.21 ETO25658.1 - 0.00021 21.4 0.0 0.00039 20.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 ETO25658.1 - 0.0032 16.9 0.0 0.0057 16.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RusA PF05866.6 ETO25661.1 - 0.065 13.6 0.0 0.11 12.9 0.0 1.3 1 1 0 1 1 1 0 Endodeoxyribonuclease RusA RHD PF00554.17 ETO25661.1 - 0.065 12.9 0.1 0.081 12.6 0.1 1.1 1 0 0 1 1 1 0 Rel homology domain (RHD) DUF4384 PF14326.1 ETO25661.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4384) DUF4470 PF14737.1 ETO25661.1 - 0.11 12.2 0.1 0.81 9.4 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4470) Helicase_C PF00271.26 ETO25662.1 - 2.8e-23 81.5 0.0 6.7e-23 80.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UvrD-helicase PF00580.16 ETO25662.1 - 0.025 13.9 2.2 0.03 13.6 1.5 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Ly49 PF08391.5 ETO25662.1 - 0.036 14.2 1.2 0.067 13.3 0.8 1.4 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF2730 PF10805.3 ETO25662.1 - 0.037 13.7 0.1 0.06 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) XPC-binding PF09280.6 ETO25662.1 - 0.084 12.3 0.5 0.2 11.1 0.4 1.6 1 0 0 1 1 1 0 XPC-binding domain DEAD PF00270.24 ETO25663.1 - 7.7e-26 90.5 0.1 1.1e-25 90.0 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2722 PF10846.3 ETO25664.1 - 1.9e-05 23.8 14.1 1.9e-05 23.8 9.8 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) PLRV_ORF5 PF01690.12 ETO25664.1 - 6.3e-05 22.3 12.0 6.3e-05 22.3 8.3 2.4 3 0 0 3 3 3 1 Potato leaf roll virus readthrough protein Zip PF02535.17 ETO25664.1 - 0.02 13.9 0.0 0.02 13.9 0.0 3.1 2 2 0 2 2 2 0 ZIP Zinc transporter DUF1510 PF07423.6 ETO25664.1 - 0.083 12.2 40.1 0.014 14.7 17.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Kei1 PF08552.6 ETO25664.1 - 0.18 11.4 0.1 0.18 11.4 0.0 3.9 3 1 0 3 3 3 0 Inositolphosphorylceramide synthase subunit Kei1 DUF3446 PF11928.3 ETO25664.1 - 0.35 11.1 28.1 0.29 11.3 7.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) Vps8 PF12816.2 ETO25665.1 - 5.6e-33 113.8 2.8 1.3e-32 112.6 1.9 1.5 1 1 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 YjeF_N PF03853.10 ETO25666.1 - 1.1e-18 67.4 0.0 1.3e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Globin PF00042.17 ETO25668.1 - 7.3e-12 45.6 3.2 1.3e-08 35.1 0.2 2.5 2 1 0 2 2 2 2 Globin NB-ARC PF00931.17 ETO25670.1 - 0.0015 17.4 0.7 0.0017 17.2 0.5 1.1 1 0 0 1 1 1 1 NB-ARC domain Methyltransf_25 PF13649.1 ETO25671.1 - 4.9e-08 33.2 0.1 1.7e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETO25671.1 - 4.8e-06 26.9 0.0 1.3e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO25671.1 - 0.00038 20.0 0.0 0.0016 18.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETO25671.1 - 0.0011 18.7 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO25671.1 - 0.0023 18.3 0.0 0.0053 17.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETO25671.1 - 0.0076 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 ETO25671.1 - 0.014 15.9 0.0 0.025 15.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TMA7 PF09072.5 ETO25673.1 - 0.023 15.1 0.7 0.055 13.9 0.5 1.6 1 0 0 1 1 1 0 Translation machinery associated TMA7 Sec15 PF04091.7 ETO25673.1 - 0.034 13.4 0.0 0.074 12.3 0.0 1.5 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like CtIP_N PF10482.4 ETO25674.1 - 0.17 11.7 5.3 0.3 10.9 3.6 1.6 1 1 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain Pkinase PF00069.20 ETO25675.1 - 2e-57 194.3 5.1 2.7e-35 121.7 0.5 2.9 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO25675.1 - 3.9e-25 88.4 6.5 8.4e-19 67.6 0.6 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase SIC PF03482.8 ETO25675.1 - 0.0029 17.2 0.1 0.0044 16.6 0.1 1.2 1 0 0 1 1 1 1 sic protein DSPn PF14671.1 ETO25676.1 - 0.00093 19.2 0.3 0.0019 18.2 0.2 1.6 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half DUF4138 PF13595.1 ETO25676.1 - 0.002 17.1 2.0 0.0035 16.3 1.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4138) Orbi_VP5 PF00901.12 ETO25676.1 - 0.02 13.1 1.0 0.035 12.3 0.7 1.3 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 DUF2435 PF10363.4 ETO25676.1 - 0.035 13.9 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2435) Vps51 PF08700.6 ETO25676.1 - 0.042 13.6 0.6 0.13 12.1 0.4 1.8 1 0 0 1 1 1 0 Vps51/Vps67 O-FucT PF10250.4 ETO25678.1 - 1e-11 44.6 0.1 7.8e-11 41.6 0.0 2.4 1 1 1 2 2 2 1 GDP-fucose protein O-fucosyltransferase Daxx PF03344.10 ETO25678.1 - 1.7 7.0 32.2 2.5 6.4 22.3 1.1 1 0 0 1 1 1 0 Daxx Family Utp14 PF04615.8 ETO25678.1 - 1.8 6.6 22.5 2.4 6.2 15.6 1.1 1 0 0 1 1 1 0 Utp14 protein TIM21 PF08294.6 ETO25679.1 - 9.7e-10 38.2 0.7 1.9e-08 34.0 0.5 2.2 1 1 0 1 1 1 1 TIM21 Coa1 PF08695.5 ETO25679.1 - 2.2e-06 27.1 0.0 3.7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Myosin_head PF00063.16 ETO25680.1 - 3.3e-178 593.9 0.2 1.3e-177 591.9 0.1 2.0 1 1 0 1 1 1 1 Myosin head (motor domain) Mac PF12464.3 ETO25680.1 - 0.049 13.6 0.6 0.16 11.9 0.4 2.0 1 1 0 1 1 1 0 Maltose acetyltransferase Spt5_N PF11942.3 ETO25682.1 - 0.00035 21.1 8.3 0.00035 21.1 5.8 4.3 3 1 1 4 4 4 1 Spt5 transcription elongation factor, acidic N-terminal FAM60A PF15396.1 ETO25684.1 - 0.0079 15.9 10.1 0.0079 15.9 7.0 1.7 2 0 0 2 2 2 1 Protein Family FAM60A Band_3_cyto PF07565.8 ETO25684.1 - 0.0085 15.6 6.5 0.0085 15.6 4.5 1.7 2 0 0 2 2 2 1 Band 3 cytoplasmic domain CDC45 PF02724.9 ETO25684.1 - 0.023 12.7 8.4 0.032 12.2 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3762 PF12591.3 ETO25684.1 - 0.11 12.4 1.5 0.15 12.1 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3762) AUX_IAA PF02309.11 ETO25684.1 - 0.12 12.1 9.4 0.38 10.4 6.4 1.8 2 0 0 2 2 2 0 AUX/IAA family NPR3 PF03666.8 ETO25684.1 - 0.14 10.6 13.8 0.25 9.8 9.5 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Spore_coat_CotO PF14153.1 ETO25684.1 - 0.22 10.9 14.8 0.024 14.0 6.8 1.8 2 1 0 2 2 2 0 Spore coat protein CotO CDK5_activator PF03261.10 ETO25684.1 - 0.25 10.6 9.5 0.53 9.5 6.6 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Hid1 PF12722.2 ETO25684.1 - 0.31 8.6 11.5 0.46 8.1 8.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.11 ETO25684.1 - 0.58 10.0 7.0 1.2 9.0 4.9 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SprA-related PF12118.3 ETO25684.1 - 0.91 8.7 21.4 0.019 14.3 10.1 1.6 2 0 0 2 2 2 0 SprA-related family DHHW PF14286.1 ETO25684.1 - 2.4 7.3 9.4 4.2 6.5 6.5 1.3 1 0 0 1 1 1 0 DHHW protein Paramyxo_ncap PF00973.14 ETO25684.1 - 6.1 5.4 10.5 8.8 4.8 7.3 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein RP-C_C PF11800.3 ETO25684.1 - 6.6 6.3 12.4 0.52 9.9 5.0 1.8 2 0 0 2 2 2 0 Replication protein C C-terminal region Menin PF05053.8 ETO25684.1 - 9.1 4.3 10.4 17 3.4 7.2 1.4 1 0 0 1 1 1 0 Menin EF-hand_7 PF13499.1 ETO25686.1 - 4.6e-17 61.9 5.6 2.4e-09 37.1 0.8 2.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 ETO25686.1 - 1.9e-16 58.0 8.8 3.3e-08 32.2 0.2 3.5 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 ETO25686.1 - 6.9e-16 57.6 5.2 5.8e-09 35.4 0.3 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO25686.1 - 7.2e-13 47.2 4.6 1.2e-06 27.9 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 ETO25686.1 - 2.4e-09 36.1 7.6 2.6e-05 23.3 0.2 3.0 3 0 0 3 3 3 2 EF hand UPF0154 PF03672.8 ETO25686.1 - 0.00014 21.4 0.0 0.088 12.4 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) TerB PF05099.8 ETO25686.1 - 0.00046 19.9 0.1 0.0021 17.7 0.0 2.0 1 1 1 2 2 2 1 Tellurite resistance protein TerB EF-hand_4 PF12763.2 ETO25686.1 - 0.007 16.0 1.8 0.28 10.9 0.0 2.3 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand NPR2 PF06218.6 ETO25688.1 - 3.8e-13 48.9 3.2 4.7e-13 48.6 2.2 1.1 1 0 0 1 1 1 1 Nitrogen permease regulator 2 bPH_5 PF10882.3 ETO25689.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial PH domain MotCF PF09158.5 ETO25690.1 - 8.7 6.0 9.8 2 8.1 0.0 3.3 3 1 0 3 3 3 0 Bacteriophage T4 MotA, C-terminal Enolase_C PF00113.17 ETO25691.1 - 8.2e-118 392.6 0.7 1.2e-117 392.1 0.5 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 ETO25691.1 - 3.9e-23 81.8 0.1 7e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 ETO25691.1 - 0.011 15.6 0.0 0.034 14.1 0.0 1.7 2 0 0 2 2 2 0 Enolase C-terminal domain-like MAAL_C PF07476.6 ETO25691.1 - 0.011 14.6 0.0 0.021 13.7 0.0 1.4 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus WD40 PF00400.27 ETO25692.1 - 1.3e-70 230.9 13.3 1.1e-12 47.2 0.2 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO25692.1 - 5.7e-10 37.9 2.3 0.013 13.6 0.1 4.1 1 1 2 4 4 4 4 Nucleoporin Nup120/160 PD40 PF07676.7 ETO25692.1 - 1e-05 25.0 9.5 5.2 6.8 0.1 5.4 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 ETO25692.1 - 0.00049 19.2 1.4 0.75 8.8 0.0 4.0 2 2 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 ETO25692.1 - 0.06 11.6 0.1 2.7 6.1 0.0 2.5 1 1 0 2 2 2 0 Cytochrome D1 heme domain Folate_carrier PF01770.13 ETO25693.1 - 1.8e-08 33.3 11.9 2.1e-08 33.1 8.3 1.1 1 0 0 1 1 1 1 Reduced folate carrier S6PP_C PF08472.5 ETO25695.1 - 0.082 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Sucrose-6-phosphate phosphohydrolase C-terminal Cyclin_N PF00134.18 ETO25696.1 - 2e-32 111.4 2.3 2.5e-32 111.1 1.6 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Sec8_exocyst PF04048.9 ETO25697.1 - 0.31 10.6 3.4 0.33 10.5 0.1 2.1 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain PAPS_reduct PF01507.14 ETO25699.1 - 6.1e-15 55.4 0.0 9.1e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family CFEM PF05730.6 ETO25699.1 - 2.9 7.7 6.0 0.31 10.8 0.3 2.1 2 0 0 2 2 2 0 CFEM domain PAPS_reduct PF01507.14 ETO25700.1 - 0.00027 20.8 0.0 0.00058 19.7 0.0 1.6 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF3847 PF12958.2 ETO25701.1 - 2.1 8.1 6.8 1.4 8.7 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) Aldo_ket_red PF00248.16 ETO25702.1 - 1.9e-32 112.2 0.1 2.3e-30 105.3 0.1 2.1 2 0 0 2 2 2 2 Aldo/keto reductase family DUF1218 PF06749.7 ETO25702.1 - 0.011 16.1 0.0 0.026 14.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1218) Iron_traffic PF04362.9 ETO25702.1 - 0.016 14.5 0.4 0.037 13.4 0.2 1.5 1 0 0 1 1 1 0 Bacterial Fe(2+) trafficking Amidohydro_1 PF01979.15 ETO25703.1 - 6.1e-28 98.4 0.0 7.3e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 ETO25703.1 - 0.012 15.6 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase Myb_DNA-bind_3 PF12776.2 ETO25704.1 - 0.018 15.6 0.6 0.045 14.3 0.2 1.7 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain SET PF00856.23 ETO25704.1 - 0.16 12.3 0.3 0.3 11.3 0.1 1.6 2 0 0 2 2 2 0 SET domain JmjN PF02375.12 ETO25705.1 - 0.0046 16.4 0.0 54 3.4 0.0 4.3 5 0 0 5 5 5 3 jmjN domain PIP5K PF01504.13 ETO25706.1 - 5.7e-22 78.0 14.7 5.6e-21 74.7 10.2 2.1 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase EphA2_TM PF14575.1 ETO25706.1 - 0.061 13.7 0.4 0.63 10.4 0.1 2.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain YajC PF02699.10 ETO25706.1 - 0.074 12.7 0.5 0.21 11.2 0.3 1.8 1 0 0 1 1 1 0 Preprotein translocase subunit G-patch_2 PF12656.2 ETO25706.1 - 0.55 10.1 0.1 0.55 10.1 0.0 3.7 5 0 0 5 5 5 0 DExH-box splicing factor binding site PIP5K PF01504.13 ETO25707.1 - 1.3e-07 31.0 0.2 2.2e-07 30.2 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase SMAP PF15477.1 ETO25707.1 - 0.067 13.4 0.7 0.1 12.8 0.5 1.3 1 0 0 1 1 1 0 Small acidic protein family 2OG-FeII_Oxy_5 PF13759.1 ETO25710.1 - 1.9e-17 63.3 0.0 6e-17 61.7 0.0 1.8 1 1 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase TFIIF_alpha PF05793.7 ETO25711.1 - 0.27 9.5 31.5 0.27 9.5 21.9 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) hNIFK_binding PF12196.3 ETO25711.1 - 0.44 9.9 4.5 1.5 8.2 2.8 2.1 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK Rgp1 PF08737.5 ETO25711.1 - 1.4 7.9 13.8 1.6 7.7 9.6 1.2 1 0 0 1 1 1 0 Rgp1 Pox_Ag35 PF03286.9 ETO25711.1 - 3.1 7.2 24.3 3.8 7.0 16.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FLO_LFY PF01698.11 ETO25711.1 - 4.4 6.0 14.0 4.2 6.1 9.7 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Vfa1 PF08432.5 ETO25711.1 - 4.9 7.1 30.4 5.7 6.9 21.1 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF966 PF06136.8 ETO25711.1 - 6.1 6.1 16.4 6.5 6.0 11.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) MIP-T3 PF10243.4 ETO25711.1 - 6.3 5.1 32.4 6.2 5.1 22.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CDC27 PF09507.5 ETO25711.1 - 9.2 5.3 32.8 11 5.0 22.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 ADP_ribosyl_GH PF03747.9 ETO25712.1 - 5.6e-38 131.3 0.0 7.4e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase DUF3753 PF12575.3 ETO25713.1 - 9 6.1 18.1 0.41 10.4 0.2 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF3753) Myco_19_kDa PF05481.7 ETO25715.1 - 0.00059 19.6 1.3 0.00098 18.9 0.9 1.3 1 0 0 1 1 1 1 Mycobacterium 19 kDa lipoprotein antigen DUF4017 PF13209.1 ETO25715.1 - 0.018 14.8 0.8 0.018 14.8 0.5 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4017) Trypan_PARP PF05887.6 ETO25715.1 - 0.61 9.8 27.9 0.021 14.6 12.9 2.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Vps26 PF03643.10 ETO25717.1 - 1e-37 129.4 7.0 1.1e-36 126.0 4.8 1.9 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 ETO25717.1 - 2.6e-14 53.2 0.4 2.7e-11 43.5 0.1 2.6 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain TrbC_Ftype PF09673.5 ETO25717.1 - 0.022 14.3 0.1 0.73 9.4 0.0 2.5 1 1 1 2 2 2 0 Type-F conjugative transfer system pilin assembly protein LPP PF04728.8 ETO25719.1 - 1.8e-05 24.4 0.6 4.3e-05 23.2 0.4 1.7 1 0 0 1 1 1 1 Lipoprotein leucine-zipper DUF1515 PF07439.6 ETO25719.1 - 0.0095 15.7 2.6 0.03 14.1 1.8 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1515) TPR_MLP1_2 PF07926.7 ETO25719.1 - 0.017 14.8 11.1 0.017 14.8 7.7 3.8 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.7 ETO25719.1 - 0.77 10.0 9.3 0.047 13.9 1.7 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein GvpK PF05121.7 ETO25719.1 - 2.7 7.8 7.0 6.5 6.6 2.0 2.7 2 0 0 2 2 2 0 Gas vesicle protein K ARID PF01388.16 ETO25720.1 - 2.4e-09 36.9 0.0 6e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain ETRAMP PF09716.5 ETO25720.1 - 0.25 11.2 0.0 0.25 11.2 0.0 2.7 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Miff PF05644.6 ETO25721.1 - 0.015 14.9 0.6 0.018 14.6 0.4 1.1 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff FANCI_S3 PF14677.1 ETO25721.1 - 0.032 13.6 1.8 0.041 13.2 1.2 1.2 1 0 0 1 1 1 0 FANCI solenoid 3 Myosin_HC-like PF07058.6 ETO25721.1 - 0.35 9.9 4.4 0.51 9.3 3.1 1.3 1 1 0 1 1 1 0 Myosin II heavy chain-like DUF1981 PF09324.5 ETO25722.1 - 1.9e-25 88.1 6.5 2.3e-25 87.9 1.1 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) NARP1 PF12569.3 ETO25722.1 - 0.014 14.2 4.7 0.033 12.9 3.2 1.6 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Peptidase_C37 PF05416.7 ETO25722.1 - 0.019 13.2 1.5 0.031 12.5 1.1 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase DUF4637 PF15470.1 ETO25722.1 - 0.047 13.3 4.9 0.1 12.1 3.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) RP-C_C PF11800.3 ETO25722.1 - 6.6 6.3 8.9 17 5.0 6.1 1.6 1 0 0 1 1 1 0 Replication protein C C-terminal region K_oxygenase PF13434.1 ETO25723.1 - 0.056 12.3 2.7 0.069 12.0 1.9 1.0 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF77 PF01910.12 ETO25725.1 - 0.1 12.2 1.8 1.1 8.9 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF77 SSP160 PF06933.6 ETO25725.1 - 6.7 4.5 9.6 11 3.8 6.6 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Muted PF14942.1 ETO25726.1 - 0.011 15.5 0.6 0.013 15.3 0.4 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein FSH1 PF03959.8 ETO25726.1 - 0.056 12.8 0.0 0.074 12.4 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Reo_sigmaC PF04582.7 ETO25727.1 - 0.0006 19.0 3.4 0.00068 18.9 1.4 1.8 1 1 1 2 2 2 1 Reovirus sigma C capsid protein Rab5-bind PF09311.6 ETO25727.1 - 0.0031 17.4 22.6 0.0031 17.4 15.7 2.8 3 0 0 3 3 3 1 Rabaptin-like protein Myosin_tail_1 PF01576.14 ETO25727.1 - 0.19 9.3 32.2 0.7 7.5 22.3 1.9 1 1 0 1 1 1 0 Myosin tail EzrA PF06160.7 ETO25727.1 - 0.39 8.8 26.5 0.46 8.5 16.2 2.6 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA Lip_prot_lig_C PF10437.4 ETO25727.1 - 0.5 10.0 3.4 11 5.7 0.2 2.7 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus Lipoprotein_6 PF01441.14 ETO25727.1 - 0.97 9.2 19.6 0.037 13.8 6.3 2.7 2 1 0 2 2 2 0 Lipoprotein CENP-Q PF13094.1 ETO25727.1 - 1.1 9.2 36.4 0.91 9.5 16.5 2.8 1 1 2 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3584 PF12128.3 ETO25727.1 - 1.3 6.2 30.4 0.6 7.3 12.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF3166 PF11365.3 ETO25727.1 - 2 8.9 13.0 3.5 8.1 7.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3166) DUF883 PF05957.8 ETO25727.1 - 2.3 8.6 20.8 3.8 7.9 3.0 4.5 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) DUF4463 PF14703.1 ETO25727.1 - 4.7 7.8 24.7 20 5.8 10.5 3.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4463) A_deaminase PF00962.17 ETO25728.1 - 1.4e-85 287.1 0.0 1.2e-84 284.1 0.0 2.0 1 1 0 1 1 1 1 Adenosine/AMP deaminase K_oxygenase PF13434.1 ETO25728.1 - 0.036 12.9 0.0 0.062 12.2 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF342 PF03961.8 ETO25729.1 - 0.17 10.2 12.6 0.25 9.7 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Phosducin PF02114.11 ETO25730.1 - 0.0017 17.1 1.7 0.26 9.9 0.4 2.1 2 0 0 2 2 2 2 Phosducin Minor_capsid_2 PF11114.3 ETO25731.1 - 0.053 13.3 0.4 0.069 13.0 0.3 1.2 1 0 0 1 1 1 0 Minor capsid protein DUF2457 PF10446.4 ETO25732.1 - 0.28 9.8 14.6 0.42 9.2 10.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sporozoite_P67 PF05642.6 ETO25732.1 - 2.4 5.8 9.0 3.4 5.4 6.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Menin PF05053.8 ETO25732.1 - 3.2 5.7 10.7 5.2 5.1 7.4 1.2 1 0 0 1 1 1 0 Menin CobT PF06213.7 ETO25732.1 - 3.4 6.7 11.4 5 6.1 7.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1510 PF07423.6 ETO25733.1 - 0.00085 18.7 7.2 0.0016 17.8 5.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Pet20 PF08692.5 ETO25733.1 - 0.0013 18.6 2.1 0.0027 17.6 1.4 1.5 1 0 0 1 1 1 1 Mitochondrial protein Pet20 Rhabdo_ncap PF00945.13 ETO25733.1 - 0.0083 14.7 1.4 0.014 13.9 1.0 1.3 1 0 0 1 1 1 1 Rhabdovirus nucleocapsid protein Anoctamin PF04547.7 ETO25733.1 - 0.011 14.3 1.0 0.044 12.4 0.3 1.9 2 0 0 2 2 2 0 Calcium-activated chloride channel NARP1 PF12569.3 ETO25733.1 - 0.018 13.8 7.2 0.027 13.2 5.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 HSP90 PF00183.13 ETO25733.1 - 0.053 11.9 15.3 0.088 11.1 10.6 1.2 1 0 0 1 1 1 0 Hsp90 protein CDC45 PF02724.9 ETO25733.1 - 0.062 11.3 6.4 0.087 10.8 4.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 ETO25733.1 - 0.11 10.4 12.3 0.17 9.8 8.5 1.2 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.7 ETO25733.1 - 0.14 12.0 11.0 0.24 11.2 7.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 VID27 PF08553.5 ETO25733.1 - 0.25 9.5 9.6 0.43 8.7 6.6 1.3 1 0 0 1 1 1 0 VID27 cytoplasmic protein Vfa1 PF08432.5 ETO25733.1 - 0.34 10.9 12.2 0.75 9.7 8.5 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Tim54 PF11711.3 ETO25733.1 - 0.4 9.2 6.2 0.81 8.2 4.3 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4512 PF14975.1 ETO25733.1 - 0.48 11.2 2.6 1.9 9.3 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) DNA_pol3_a_NII PF11490.3 ETO25733.1 - 0.62 9.6 20.6 0.71 9.5 12.9 2.1 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II DUF853 PF05872.7 ETO25733.1 - 0.63 8.3 2.3 3.6 5.8 1.5 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Daxx PF03344.10 ETO25733.1 - 0.86 8.0 15.9 1.3 7.4 11.0 1.1 1 0 0 1 1 1 0 Daxx Family Borrelia_P83 PF05262.6 ETO25733.1 - 0.97 7.6 10.1 1.4 7.0 7.0 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Prog_receptor PF02161.10 ETO25733.1 - 1 8.1 6.0 1.5 7.5 4.2 1.1 1 0 0 1 1 1 0 Progesterone receptor FAM176 PF14851.1 ETO25733.1 - 1.1 8.8 8.7 3.9 7.1 5.6 2.1 2 0 0 2 2 2 0 FAM176 family Paf1 PF03985.8 ETO25733.1 - 2.7 6.6 18.8 4.5 5.8 13.0 1.3 1 0 0 1 1 1 0 Paf1 RRN3 PF05327.6 ETO25733.1 - 3.5 5.6 10.8 5.7 4.9 7.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TRAP_alpha PF03896.11 ETO25733.1 - 4.8 6.0 12.8 8.5 5.2 8.9 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DDHD PF02862.12 ETO25733.1 - 5.9 6.6 7.1 5.5 6.7 3.9 1.6 2 0 0 2 2 2 0 DDHD domain Pox_Ag35 PF03286.9 ETO25733.1 - 7.8 5.9 15.8 14 5.0 11.0 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein ATP-synt_E PF05680.7 ETO25733.1 - 9.9 6.1 10.9 24 4.9 7.5 1.6 1 0 0 1 1 1 0 ATP synthase E chain WD40 PF00400.27 ETO25734.1 - 4.9e-61 200.5 26.5 8.4e-13 47.6 0.5 7.2 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO25734.1 - 1.1e-09 36.9 7.2 0.012 13.7 0.1 5.1 2 2 3 5 5 5 5 Nucleoporin Nup120/160 DUF912 PF06024.7 ETO25735.1 - 0.00068 19.6 0.5 0.00068 19.6 0.4 3.3 1 1 2 3 3 3 1 Nucleopolyhedrovirus protein of unknown function (DUF912) UPF0233 PF06781.7 ETO25735.1 - 0.013 15.0 0.0 0.013 15.0 0.0 3.3 4 1 0 4 4 4 0 Uncharacterised protein family (UPF0233) ABC2_membrane_3 PF12698.2 ETO25735.1 - 0.039 12.9 0.0 0.071 12.1 0.0 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein ATG27 PF09451.5 ETO25735.1 - 0.3 10.2 11.0 0.052 12.7 3.3 2.3 1 1 1 2 2 2 0 Autophagy-related protein 27 DUF966 PF06136.8 ETO25735.1 - 0.71 9.2 20.0 0.26 10.6 8.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF966) RIC3 PF15361.1 ETO25735.1 - 2.5 8.3 0.0 2.5 8.3 0.0 3.1 2 1 1 3 3 3 0 Resistance to inhibitors of cholinesterase homologue 3 FAM60A PF15396.1 ETO25735.1 - 4 7.1 17.2 0.3 10.7 5.9 2.2 2 0 0 2 2 2 0 Protein Family FAM60A GPCR_chapero_1 PF11904.3 ETO25735.1 - 6.4 5.8 17.6 0.78 8.8 0.6 2.1 1 1 1 2 2 2 0 GPCR-chaperone zf-TRAF PF02176.13 ETO25736.1 - 1.7e-06 28.2 3.3 1.7e-06 28.2 2.3 1.9 1 1 1 2 2 2 1 TRAF-type zinc finger Sina PF03145.11 ETO25736.1 - 0.0023 17.6 2.1 0.0048 16.5 1.5 1.6 1 0 0 1 1 1 1 Seven in absentia protein family DUF1703 PF08011.6 ETO25736.1 - 0.068 12.9 0.6 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1703) Phasin PF05597.6 ETO25737.1 - 0.0059 16.3 1.6 0.0059 16.3 1.1 1.6 2 0 0 2 2 2 1 Poly(hydroxyalcanoate) granule associated protein (phasin) Phe_tRNA-synt_N PF02912.13 ETO25737.1 - 0.039 13.6 2.3 1.4 8.6 0.0 3.2 3 1 0 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain ALMT PF11744.3 ETO25737.1 - 0.064 11.9 2.8 0.1 11.2 1.9 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2522 PF10747.4 ETO25737.1 - 0.07 13.1 0.5 0.07 13.1 0.3 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2522) GrpE PF01025.14 ETO25737.1 - 0.12 11.9 5.8 0.18 11.3 4.0 1.4 1 0 0 1 1 1 0 GrpE Enkurin PF13864.1 ETO25737.1 - 0.12 12.5 9.0 0.12 12.6 3.8 2.6 2 1 1 3 3 3 0 Calmodulin-binding YusW PF14039.1 ETO25737.1 - 0.28 11.4 3.9 1.8 8.8 0.2 2.6 1 1 1 2 2 2 0 YusW-like protein Baculo_PEP_C PF04513.7 ETO25737.1 - 0.55 10.0 3.7 0.93 9.3 1.0 2.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CCDC-167 PF15188.1 ETO25737.1 - 0.82 9.6 8.1 1.3 9.0 3.8 2.2 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DUF2762 PF10960.3 ETO25737.1 - 0.93 9.2 9.2 6.6 6.5 0.1 3.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2762) IncA PF04156.9 ETO25737.1 - 5.3 6.5 7.2 9 5.8 5.0 1.4 1 0 0 1 1 1 0 IncA protein HECT PF00632.20 ETO25738.1 - 2.3e-39 135.4 0.6 5.1e-39 134.2 0.1 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 ETO25738.1 - 1.7e-10 41.0 0.6 8.9e-09 35.4 0.0 2.6 2 0 0 2 2 2 1 SPRY domain WD40 PF00400.27 ETO25739.1 - 8e-64 209.4 26.9 4.2e-11 42.2 1.5 7.4 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO25739.1 - 5.4e-15 54.5 2.2 0.021 12.9 0.0 6.0 1 1 4 6 6 6 6 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO25739.1 - 0.0007 19.0 7.5 0.11 11.7 0.8 3.2 2 1 0 3 3 3 3 Domain of unknown function (DUF4221) Methyltransf_25 PF13649.1 ETO25739.1 - 0.12 12.7 0.0 7.2 7.0 0.0 3.4 3 2 0 3 3 3 0 Methyltransferase domain Bcl-2_3 PF15286.1 ETO25739.1 - 0.21 12.0 2.2 3.9 7.9 0.1 3.0 2 1 1 3 3 3 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like CHU_C PF13585.1 ETO25739.1 - 0.49 10.2 5.3 2.1 8.3 0.3 3.9 4 1 0 5 5 5 0 C-terminal domain of CHU protein family Mis12 PF05859.7 ETO25740.1 - 1.5e-05 24.8 4.8 1.5e-05 24.8 3.3 1.8 2 0 0 2 2 2 1 Mis12 protein DUF1814 PF08843.6 ETO25740.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF1814) EMP24_GP25L PF01105.19 ETO25740.1 - 0.27 10.9 7.0 0.082 12.6 2.2 2.0 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD APG6 PF04111.7 ETO25740.1 - 3.5 6.5 17.4 0.15 11.0 8.1 1.5 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF641 PF04859.7 ETO25740.1 - 8.2 6.1 12.4 1.3 8.7 2.0 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Microtub_bind PF13931.1 ETO25741.1 - 0.31 11.1 9.9 0.46 10.6 6.9 1.2 1 0 0 1 1 1 0 Kinesin-associated microtubule-binding Menin PF05053.8 ETO25741.1 - 0.35 8.9 6.5 0.42 8.7 4.5 1.1 1 0 0 1 1 1 0 Menin Secretin_N_2 PF07655.8 ETO25741.1 - 1.2 9.6 27.8 2.9 8.3 19.3 1.7 1 1 0 1 1 1 0 Secretin N-terminal domain DUF3245 PF11595.3 ETO25742.1 - 0.055 13.7 10.8 0.11 12.7 7.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Cwf_Cwc_15 PF04889.7 ETO25742.1 - 0.49 10.0 15.1 0.95 9.1 10.4 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 ETO25742.1 - 3 5.7 8.7 3.8 5.4 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.6 ETO25742.1 - 3 7.3 17.1 4.8 6.6 11.8 1.2 1 0 0 1 1 1 0 PPP4R2 WD40 PF00400.27 ETO25743.1 - 3.3e-15 55.2 8.9 2e-06 27.4 0.2 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat CAML PF14963.1 ETO25745.1 - 0.28 10.5 4.8 0.56 9.5 3.4 1.4 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand YMF19 PF02326.10 ETO25745.1 - 0.47 11.0 3.0 0.34 11.5 0.2 2.2 2 0 0 2 2 2 0 Plant ATP synthase F0 C2 PF00168.25 ETO25747.1 - 9.3e-05 22.1 0.2 0.00026 20.7 0.1 1.7 1 0 0 1 1 1 1 C2 domain Dynamin_N PF00350.18 ETO25748.1 - 2.7e-26 92.3 0.2 9.4e-26 90.6 0.1 2.0 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 ETO25748.1 - 8.6e-26 90.3 4.3 1.7e-25 89.4 3.0 1.5 1 0 0 1 1 1 1 Dynamin central region GED PF02212.13 ETO25748.1 - 8.7e-07 28.7 6.8 5.4e-06 26.2 1.4 3.5 2 1 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 ETO25748.1 - 0.0018 18.1 0.2 0.01 15.7 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.1 ETO25748.1 - 0.035 13.6 0.0 0.08 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF718 PF05336.8 ETO25749.1 - 2.3e-30 104.4 0.1 2.8e-30 104.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF718) Coiled-coil_56 PF09813.4 ETO25749.1 - 0.0029 17.5 0.0 0.0037 17.2 0.0 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 Phospholip_A2_2 PF05826.7 ETO25750.1 - 4.4 7.3 11.7 0.76 9.7 2.4 2.4 1 1 1 2 2 2 0 Phospholipase A2 PDR_CDR PF06422.7 ETO25751.1 - 0.014 15.0 0.7 0.031 13.9 0.5 1.5 1 0 0 1 1 1 0 CDR ABC transporter Fib_alpha PF08702.5 ETO25751.1 - 0.04 14.0 26.9 0.18 11.9 7.9 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family POTRA_2 PF08479.6 ETO25751.1 - 0.091 12.4 4.6 0.17 11.5 0.2 2.7 3 0 0 3 3 3 0 POTRA domain, ShlB-type Cas_NE0113 PF09623.5 ETO25751.1 - 0.76 9.1 4.9 0.18 11.2 0.6 1.9 2 0 0 2 2 2 0 CRISPR-associated protein NE0113 (Cas_NE0113) DUF4200 PF13863.1 ETO25751.1 - 1.1 9.1 30.6 0.46 10.4 1.4 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) SIMPL PF04402.9 ETO25751.1 - 1.4 8.6 6.0 0.85 9.4 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF541) DOG1 PF14144.1 ETO25751.1 - 3.1 7.8 8.1 6.2 6.9 0.5 3.1 3 0 0 3 3 3 0 Seed dormancy control V_ATPase_I PF01496.14 ETO25751.1 - 3.5 5.3 18.8 4.1 5.1 13.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Bap31 PF05529.7 ETO25751.1 - 3.7 6.9 28.5 0.1 12.0 4.5 3.6 2 2 1 3 3 3 0 B-cell receptor-associated protein 31-like DUF948 PF06103.6 ETO25751.1 - 5.4 6.9 16.2 2.7 7.9 0.6 3.5 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) RhoGEF PF00621.15 ETO25753.1 - 5.6e-05 23.1 5.9 5.6e-05 23.1 4.1 2.6 1 1 1 2 2 2 2 RhoGEF domain Bindin PF02084.10 ETO25755.1 - 0.039 13.9 0.9 0.039 13.9 0.6 1.5 2 0 0 2 2 2 0 Bindin Pkinase PF00069.20 ETO25756.1 - 8.5e-07 28.3 1.3 1.1e-06 27.9 0.9 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO25756.1 - 0.0013 17.8 0.3 0.0018 17.3 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 ETO25757.1 - 2.5e-56 190.7 0.0 3.6e-56 190.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO25757.1 - 6.1e-25 87.7 0.0 7.9e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO25757.1 - 4.7e-05 22.5 0.0 6.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETO25757.1 - 8.4e-05 22.4 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 ETO25757.1 - 0.00058 18.9 0.0 0.00091 18.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 ETO25757.1 - 0.0062 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Cor1 PF04803.7 ETO25757.1 - 0.6 9.8 3.9 0.44 10.2 0.6 2.2 2 1 1 3 3 3 0 Cor1/Xlr/Xmr conserved region FYVE PF01363.16 ETO25759.1 - 0.028 14.3 3.7 0.051 13.4 2.4 1.6 1 1 0 1 1 1 0 FYVE zinc finger Neisseria_TspB PF05616.8 ETO25760.1 - 0.13 10.6 0.0 0.17 10.2 0.0 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Virulence_fact PF13769.1 ETO25761.1 - 0.0073 16.1 0.7 0.13 12.1 0.0 2.6 1 1 1 2 2 2 1 Virulence factor Pyrophosphatase PF00719.14 ETO25761.1 - 0.097 12.1 2.2 0.065 12.6 0.2 1.6 2 0 0 2 2 2 0 Inorganic pyrophosphatase KxDL PF10241.4 ETO25761.1 - 0.76 9.7 5.0 1.1 9.1 1.5 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein IBB PF01749.15 ETO25761.1 - 1.6 8.9 10.3 1.1 9.4 1.3 2.7 3 0 0 3 3 3 0 Importin beta binding domain Ank_2 PF12796.2 ETO25762.1 - 0.033 14.5 0.0 0.095 13.0 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) WD40 PF00400.27 ETO25763.1 - 7.7e-66 215.8 20.1 9.9e-12 44.2 0.3 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO25763.1 - 2.1e-14 52.5 4.6 0.0018 16.5 0.0 5.5 1 1 4 5 5 5 5 Nucleoporin Nup120/160 DUF606 PF04657.8 ETO25764.1 - 5e-37 127.0 22.2 5.8e-21 75.0 5.7 3.3 3 0 0 3 3 3 3 Protein of unknown function, DUF606 Acyl-CoA_dh_1 PF00441.19 ETO25765.1 - 1.8e-39 135.2 0.0 2.2e-39 134.9 0.0 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 ETO25765.1 - 1.4e-19 70.6 0.0 1.7e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 ETO25766.1 - 1.1e-26 93.5 0.0 3.9e-26 91.8 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 ETO25766.1 - 2e-17 62.4 0.0 3.8e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HpaB_N PF11794.3 ETO25766.1 - 0.034 13.5 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Helicase_C PF00271.26 ETO25767.1 - 6.3e-08 32.3 0.0 2.1e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 ETO25767.1 - 1.5 8.9 15.5 0.018 15.0 4.4 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 ETO25767.1 - 3.7 7.4 14.0 0.22 11.3 5.0 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 ETO25767.1 - 6.8 6.4 13.0 0.12 12.1 2.7 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SNF2_N PF00176.18 ETO25768.1 - 9.6e-57 192.0 0.0 7.3e-51 172.7 0.0 3.4 2 1 0 2 2 2 2 SNF2 family N-terminal domain DivIC PF04977.10 ETO25769.1 - 0.00066 19.1 0.4 0.00066 19.1 0.3 3.9 2 1 1 3 3 3 1 Septum formation initiator Prp19 PF08606.6 ETO25769.1 - 0.0079 15.9 7.5 0.27 10.9 0.4 3.0 2 0 0 2 2 2 2 Prp19/Pso4-like Reo_sigmaC PF04582.7 ETO25769.1 - 0.12 11.5 3.9 0.43 9.6 0.9 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein GvpK PF05121.7 ETO25769.1 - 4.8 7.0 14.1 0.52 10.1 0.6 3.2 4 0 0 4 4 4 0 Gas vesicle protein K UPF0118 PF01594.11 ETO25769.1 - 5.7 5.8 9.7 2.5 6.9 0.3 2.7 2 1 1 3 3 3 0 Domain of unknown function DUF20 Rap_GAP PF02145.10 ETO25770.1 - 5.9e-51 172.5 0.4 1.2e-50 171.5 0.3 1.5 1 0 0 1 1 1 1 Rap/ran-GAP MANEC PF07502.9 ETO25771.1 - 1 9.3 3.9 1.1 9.3 1.7 1.6 1 1 0 1 1 1 0 MANEC domain Sigma_reg_N PF13800.1 ETO25772.1 - 0.06 13.3 0.1 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal PRK PF00485.13 ETO25773.1 - 0.71 9.4 7.2 0.23 10.9 0.7 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.15 ETO25775.1 - 3.1e-85 286.2 2.0 9.6e-85 284.5 1.4 1.6 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO25775.1 - 5.8e-09 35.4 0.3 0.00031 20.0 0.0 3.2 3 0 0 3 3 3 3 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETO25775.1 - 7.2e-05 22.7 0.0 0.018 15.0 0.0 3.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 ETO25775.1 - 0.044 14.2 0.0 2 8.9 0.0 2.9 3 0 0 3 3 3 0 Miro-like protein SRPRB PF09439.5 ETO25775.1 - 0.072 12.3 0.1 0.84 8.8 0.0 2.5 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit Bromodomain PF00439.20 ETO25776.1 - 5e-19 67.9 3.1 8.2e-19 67.3 2.2 1.4 1 0 0 1 1 1 1 Bromodomain EF-hand_7 PF13499.1 ETO25777.1 - 3.6e-10 39.8 6.4 1.2e-08 34.9 0.5 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 ETO25777.1 - 6.5e-08 32.0 2.6 0.00034 20.1 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 ETO25777.1 - 7.1e-08 31.2 4.2 2.9e-05 23.0 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 ETO25777.1 - 5e-07 29.0 3.9 0.018 14.8 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 ETO25777.1 - 1.5e-06 27.2 3.3 2.2e-06 26.7 0.1 2.6 2 1 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.4 ETO25777.1 - 0.057 13.4 0.5 6 6.9 0.2 2.3 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 ETO25777.1 - 0.17 11.6 1.3 2.1 8.0 0.4 2.1 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand WD40 PF00400.27 ETO25778.1 - 1.3e-65 215.0 21.5 1.6e-14 53.1 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO25778.1 - 1.3e-09 38.0 0.9 0.0036 17.0 0.0 4.0 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 ETO25778.1 - 1.7e-07 30.4 9.7 0.011 14.5 0.4 5.0 1 1 3 4 4 4 3 Nup133 N terminal like Nbas_N PF15492.1 ETO25778.1 - 2.8e-06 26.6 1.4 1.7 7.6 0.0 4.1 1 1 2 4 4 4 3 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 ETO25778.1 - 0.00011 20.6 4.3 0.0026 16.1 0.1 3.0 1 1 2 3 3 3 2 Cytochrome D1 heme domain DUF285 PF03382.9 ETO25778.1 - 0.0077 15.7 0.4 2.2 7.8 0.1 2.9 2 1 0 2 2 2 1 Mycoplasma protein of unknown function, DUF285 PD40 PF07676.7 ETO25778.1 - 0.011 15.3 6.0 0.45 10.2 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Hira PF07569.6 ETO25778.1 - 0.043 13.0 1.0 3 6.9 0.0 3.7 2 1 3 5 5 5 0 TUP1-like enhancer of split Spore_YhcN_YlaJ PF09580.5 ETO25779.1 - 0.0005 20.2 3.6 0.00064 19.8 2.5 1.3 1 0 0 1 1 1 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF2457 PF10446.4 ETO25779.1 - 0.024 13.3 6.1 0.03 13.0 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF506 PF04720.7 ETO25779.1 - 0.19 11.3 5.2 0.35 10.4 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF506) RCR PF12273.3 ETO25779.1 - 0.38 11.3 4.6 0.61 10.6 2.3 2.1 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red NOA36 PF06524.7 ETO25779.1 - 0.43 9.7 6.9 0.78 8.9 4.8 1.4 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.8 ETO25779.1 - 0.51 9.9 6.3 0.86 9.1 4.1 1.5 1 1 0 1 1 1 0 Sigma-70, non-essential region Asp PF00026.18 ETO25781.1 - 5.5e-31 107.9 3.2 5.4e-29 101.4 2.2 2.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETO25781.1 - 3.5e-05 23.8 0.0 0.00035 20.5 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Cnd1_N PF12922.2 ETO25782.1 - 0.14 11.7 5.7 8.1 6.0 0.0 3.6 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1, N-term Spore_YhcN_YlaJ PF09580.5 ETO25782.1 - 4.3 7.4 17.8 0.21 11.7 6.6 2.4 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) bZIP_C PF12498.3 ETO25782.1 - 8 7.7 13.3 3.4 8.9 0.5 2.4 2 0 0 2 2 2 0 Basic leucine-zipper C terminal Cation_efflux PF01545.16 ETO25785.1 - 1.8e-13 50.2 10.9 2.1e-13 49.9 1.2 2.2 2 1 0 2 2 2 2 Cation efflux family DcuC PF03606.10 ETO25785.1 - 0.007 14.6 1.1 0.0083 14.4 0.2 1.4 2 0 0 2 2 2 1 C4-dicarboxylate anaerobic carrier EOS1 PF12326.3 ETO25785.1 - 0.077 12.6 3.2 0.048 13.3 1.0 1.7 1 1 1 2 2 2 0 N-glycosylation protein CAAD PF14159.1 ETO25785.1 - 0.095 12.3 0.3 6.7 6.4 0.0 2.4 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase TctB PF07331.6 ETO25785.1 - 0.1 12.2 0.1 0.1 12.2 0.1 2.1 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Cnd1_N PF12922.2 ETO25785.1 - 0.11 12.1 0.0 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term DUF1282 PF06930.7 ETO25785.1 - 0.12 12.0 3.9 1.3 8.6 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) ETRAMP PF09716.5 ETO25785.1 - 0.81 9.6 11.1 0.66 9.9 2.1 3.1 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Protocadherin PF08374.6 ETO25785.1 - 0.86 9.2 4.4 0.2 11.2 0.7 1.7 2 0 0 2 2 2 0 Protocadherin OST3_OST6 PF04756.8 ETO25785.1 - 1 8.9 7.7 3.2 7.3 1.8 3.0 2 1 1 3 3 3 0 OST3 / OST6 family ATP-synt_8 PF00895.15 ETO25785.1 - 4 7.7 5.5 0.73 10.0 0.3 2.5 2 0 0 2 2 2 0 ATP synthase protein 8 Kelch_1 PF01344.20 ETO25786.1 - 7.4e-09 35.0 1.9 3.2e-05 23.3 0.1 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO25786.1 - 8.2e-09 35.2 0.8 0.00035 20.6 0.0 3.6 3 1 1 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO25786.1 - 0.00015 21.8 0.0 0.0019 18.3 0.0 2.7 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO25786.1 - 0.00017 21.2 2.9 0.0002 21.0 0.0 2.6 3 1 1 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO25786.1 - 0.00037 20.1 4.7 0.0041 16.8 0.1 3.4 4 0 0 4 4 4 1 Kelch motif F-box PF00646.28 ETO25787.1 - 0.00078 19.0 0.5 0.003 17.1 0.2 2.1 2 0 0 2 2 2 1 F-box domain Folate_carrier PF01770.13 ETO25788.1 - 0.15 10.5 2.4 0.27 9.7 1.6 1.4 1 0 0 1 1 1 0 Reduced folate carrier PH PF00169.24 ETO25789.1 - 5.9e-16 58.5 0.9 1.1e-15 57.6 0.6 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 ETO25789.1 - 5.3e-09 36.0 0.4 8.3e-09 35.3 0.3 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 ETO25789.1 - 2.9e-08 33.5 0.7 5.3e-08 32.6 0.5 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 ETO25789.1 - 4.8e-07 30.0 8.5 5.9e-07 29.7 3.1 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.1 ETO25789.1 - 0.0055 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain FAD_binding_1 PF00667.15 ETO25790.1 - 8.8e-40 136.4 0.1 2.3e-39 135.1 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.20 ETO25790.1 - 3.5e-39 134.0 0.4 6.9e-39 133.1 0.3 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 ETO25790.1 - 5.4e-13 49.4 0.0 1.7e-12 47.8 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain MarR_2 PF12802.2 ETO25790.1 - 0.091 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 MarR family ETRAMP PF09716.5 ETO25790.1 - 0.19 11.6 5.4 3.3 7.7 0.4 2.8 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) NPR3 PF03666.8 ETO25793.1 - 3.6e-19 68.6 2.0 3.6e-19 68.6 1.4 1.6 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 YqfQ PF14181.1 ETO25794.1 - 0.24 11.4 3.1 0.28 11.2 2.1 1.2 1 0 0 1 1 1 0 YqfQ-like protein Pkinase PF00069.20 ETO25795.1 - 4.2e-13 49.0 0.0 8e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO25795.1 - 6.2e-13 48.4 0.0 9.1e-13 47.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Herpes_US9 PF06072.6 ETO25795.1 - 0.49 10.2 0.1 0.49 10.2 0.1 2.3 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 RR_TM4-6 PF06459.7 ETO25795.1 - 2.8 7.7 9.4 5.3 6.8 6.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3807 PF12720.2 ETO25796.1 - 1.6 8.8 24.5 2.2 8.3 17.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) MAP7 PF05672.6 ETO25796.1 - 1.9 7.8 38.6 2.5 7.4 26.7 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Band_3_cyto PF07565.8 ETO25796.1 - 8.7 5.7 11.6 10 5.5 8.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain AAA_23 PF13476.1 ETO25796.1 - 9.3 6.5 17.9 14 5.9 12.4 1.2 1 0 0 1 1 1 0 AAA domain PspB PF06667.7 ETO25797.1 - 0.0067 16.3 1.5 0.41 10.5 0.0 3.3 3 0 0 3 3 3 2 Phage shock protein B DUF929 PF06053.6 ETO25798.1 - 0.072 12.1 0.5 0.088 11.8 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF929) CENP-B_dimeris PF09026.5 ETO25798.1 - 0.99 9.6 4.2 1.6 8.9 2.9 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SPOUT_MTase PF02590.12 ETO25800.1 - 0.26 11.0 6.4 0.44 10.2 4.4 1.4 1 1 0 1 1 1 0 Predicted SPOUT methyltransferase CAML PF14963.1 ETO25800.1 - 0.36 10.1 6.2 0.55 9.5 4.3 1.4 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand TrwC PF08751.6 ETO25800.1 - 9.5 5.5 14.4 0.46 9.8 4.1 2.0 1 1 1 2 2 2 0 TrwC relaxase Na_Ca_ex PF01699.19 ETO25801.1 - 0.0089 15.6 1.5 0.0089 15.6 1.0 2.1 2 1 0 2 2 2 1 Sodium/calcium exchanger protein Tmp39 PF10271.4 ETO25801.1 - 0.12 10.9 0.1 0.12 10.9 0.1 2.0 2 0 0 2 2 2 0 Putative transmembrane protein EF-hand_7 PF13499.1 ETO25802.1 - 1e-08 35.1 2.3 2.6e-08 33.8 1.6 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 ETO25802.1 - 1.4e-08 33.7 3.7 3.6e-08 32.4 1.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 ETO25802.1 - 1.1e-07 31.1 3.6 2.1e-07 30.2 0.3 2.6 2 1 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 ETO25802.1 - 2.7e-07 29.4 0.5 2.7e-07 29.4 0.4 2.8 3 1 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 ETO25802.1 - 0.0018 17.8 7.0 0.015 14.8 1.4 2.7 2 1 1 3 3 3 2 EF-hand domain pair MscS_TM PF12794.2 ETO25802.1 - 0.02 13.5 0.2 0.041 12.5 0.1 1.5 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF2413 PF10310.4 ETO25802.1 - 0.089 11.5 15.1 0.11 11.2 10.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Neur_chan_memb PF02932.11 ETO25802.1 - 0.51 10.1 4.6 0.7 9.7 3.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1510 PF07423.6 ETO25802.1 - 1.4 8.2 18.0 2.3 7.5 12.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Zn_ribbon_2 PF12674.2 ETO25802.1 - 8.9 6.7 12.0 0.87 9.9 4.1 2.3 2 1 1 3 3 3 0 Putative zinc ribbon domain Sec5 PF15469.1 ETO25803.1 - 0.0017 18.1 2.7 0.0021 17.7 1.9 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec5 Agro_virD5 PF04730.7 ETO25803.1 - 0.3 9.0 8.0 0.35 8.8 5.5 1.0 1 0 0 1 1 1 0 Agrobacterium VirD5 protein Sporozoite_P67 PF05642.6 ETO25803.1 - 0.51 8.1 15.2 0.16 9.8 8.0 1.7 1 1 1 2 2 2 0 Sporozoite P67 surface antigen SH3_8 PF13457.1 ETO25803.1 - 3.4 7.9 14.2 0.24 11.5 4.4 2.7 1 1 2 3 3 3 0 SH3-like domain ECH_C PF13766.1 ETO25804.1 - 1.4e-33 115.5 0.1 2.5e-33 114.7 0.0 1.4 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 ETO25804.1 - 2.1e-23 82.6 0.0 1.2e-22 80.2 0.0 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family OTU PF02338.14 ETO25805.1 - 1.5e-19 70.7 0.3 1.5e-19 70.7 0.2 3.4 3 0 0 3 3 3 1 OTU-like cysteine protease SEC-C PF02810.10 ETO25805.1 - 8e-06 25.2 13.2 1.7e-05 24.1 9.2 1.6 1 0 0 1 1 1 1 SEC-C motif Peptidase_C65 PF10275.4 ETO25805.1 - 0.0096 15.2 1.4 0.0096 15.2 1.0 2.8 2 0 0 2 2 2 1 Peptidase C65 Otubain Glutaredoxin2_C PF04399.8 ETO25806.1 - 1.9 8.0 11.8 4.3 6.9 0.1 3.3 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain Metal_resist PF13801.1 ETO25806.1 - 2.2 8.2 7.4 1.8 8.5 0.5 2.6 2 0 0 2 2 2 0 Heavy-metal resistance Nicastrin PF05450.10 ETO25807.1 - 9.3e-37 126.4 0.5 1.8e-36 125.5 0.3 1.5 1 0 0 1 1 1 1 Nicastrin Peptidase_M28 PF04389.12 ETO25807.1 - 8.8e-06 25.5 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Herpes_UL52 PF03121.10 ETO25808.1 - 3.9e-11 42.5 0.5 7.8e-11 41.5 0.3 1.5 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase TFIIS_M PF07500.9 ETO25809.1 - 2.8e-16 59.6 18.7 7.5e-16 58.2 3.6 3.4 2 1 1 3 3 3 2 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 ETO25809.1 - 9.3e-06 26.1 0.8 4.7e-05 23.8 0.1 2.6 2 1 0 2 2 2 1 SPOC domain PAC2 PF09754.4 ETO25809.1 - 0.31 10.8 0.1 0.31 10.8 0.1 1.9 2 0 0 2 2 2 0 PAC2 family Protocadherin PF08374.6 ETO25810.1 - 0.35 10.4 4.4 0.53 9.8 3.0 1.2 1 0 0 1 1 1 0 Protocadherin Katanin_con80 PF13925.1 ETO25812.1 - 0.0087 15.8 1.4 0.012 15.4 0.8 1.5 1 1 0 1 1 1 1 con80 domain of Katanin Peptidase_M75 PF09375.5 ETO25812.1 - 0.095 11.9 0.2 0.1 11.8 0.2 1.2 1 0 0 1 1 1 0 Imelysin Pkinase PF00069.20 ETO25813.1 - 4e-23 81.8 0.3 1.2e-22 80.3 0.2 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO25813.1 - 1.6e-13 50.3 0.1 2.1e-13 49.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO25813.1 - 4.4e-06 25.9 0.1 7.6e-06 25.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_C11 PF03415.9 ETO25813.1 - 0.01 14.8 0.1 0.016 14.1 0.0 1.3 1 1 0 1 1 1 0 Clostripain family zf-DHHC PF01529.15 ETO25814.1 - 2.3e-33 115.0 8.3 5.1e-33 113.8 5.8 1.6 1 1 0 1 1 1 1 DHHC palmitoyltransferase Herpes_LMP1 PF05297.6 ETO25814.1 - 0.9 8.3 5.4 20 3.9 0.0 2.2 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) Afi1 PF07792.7 ETO25814.1 - 2.1 8.3 6.4 0.23 11.4 0.7 2.1 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Rsbr_N PF08678.5 ETO25815.1 - 0.044 13.6 4.6 0.31 10.9 2.4 2.2 1 1 1 2 2 2 0 Rsbr N terminal CmcH_NodU PF02543.10 ETO25815.1 - 0.056 12.5 5.9 0.082 12.0 4.1 1.2 1 0 0 1 1 1 0 Carbamoyltransferase DUF4407 PF14362.1 ETO25815.1 - 1.1 8.1 11.3 1.5 7.7 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LMBR1 PF04791.11 ETO25815.1 - 1.4 7.3 5.6 2 6.8 3.9 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Apt1 PF10351.4 ETO25815.1 - 2.3 7.0 16.9 3.6 6.3 11.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4220 PF13968.1 ETO25815.1 - 2.8 6.9 8.7 4.9 6.1 6.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) CLPTM1 PF05602.7 ETO25815.1 - 3.5 6.2 10.3 0.63 8.6 4.2 1.7 2 0 0 2 2 2 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) Ndc1_Nup PF09531.5 ETO25815.1 - 5.9 5.1 8.4 6.6 5.0 5.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hid1 PF12722.2 ETO25815.1 - 9.7 3.7 17.4 13 3.2 12.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein B56 PF01603.15 ETO25816.1 - 2.9e-47 161.2 9.7 3.3e-38 131.3 0.7 2.0 1 1 1 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) SIR2 PF02146.12 ETO25817.1 - 3.2e-23 82.3 0.1 1.2e-17 64.2 0.0 2.4 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.17 ETO25817.1 - 0.0012 18.5 0.1 0.33 10.7 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF3592 PF12158.3 ETO25820.1 - 0.87 9.3 3.5 21 4.8 2.4 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3592) Rac1 PF09632.5 ETO25821.1 - 0.019 14.0 0.1 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Rac1-binding domain Cys_rich_KTR PF14205.1 ETO25821.1 - 0.025 14.0 0.3 0.057 12.8 0.2 1.7 1 0 0 1 1 1 0 Cysteine-rich KTR HTH_12 PF08461.5 ETO25821.1 - 0.12 12.1 0.1 0.29 10.8 0.0 1.7 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain Ctr PF04145.10 ETO25822.1 - 1 9.4 8.3 0.17 11.9 0.4 3.0 3 0 0 3 3 3 0 Ctr copper transporter family GAGA_bind PF06217.7 ETO25823.1 - 0.11 12.4 18.6 0.12 12.2 12.9 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Peptidase_U57 PF05582.7 ETO25823.1 - 1.9 7.3 11.3 2.5 6.9 7.8 1.2 1 0 0 1 1 1 0 YabG peptidase U57 DDHD PF02862.12 ETO25823.1 - 8.8 6.0 13.9 13 5.5 9.6 1.2 1 0 0 1 1 1 0 DDHD domain YtfJ_HI0045 PF09695.5 ETO25825.1 - 0.033 13.5 0.2 0.057 12.7 0.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (YtfJ_HI0045) EMP24_GP25L PF01105.19 ETO25827.1 - 0.00011 21.9 0.7 0.00015 21.5 0.5 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SAM_1 PF00536.25 ETO25829.1 - 9e-18 64.2 0.6 1.3e-08 34.8 0.1 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO25829.1 - 4.7e-14 51.9 0.3 8.5e-07 28.7 0.0 2.6 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) Ste50p-SAM PF09235.5 ETO25829.1 - 0.0017 18.3 0.0 0.03 14.3 0.0 2.7 2 0 0 2 2 2 1 Ste50p, sterile alpha motif SAM_PNT PF02198.11 ETO25829.1 - 0.0048 16.6 1.0 0.15 11.8 0.1 2.8 1 1 1 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain Agenet PF05641.7 ETO25829.1 - 0.0074 16.4 0.6 0.0074 16.4 0.4 2.4 2 1 0 2 2 2 1 Agenet domain DUF912 PF06024.7 ETO25830.1 - 0.56 10.2 8.0 1.8 8.6 5.5 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) p31comet PF06581.7 ETO25832.1 - 0.53 9.0 6.7 0.085 11.7 0.9 2.1 1 1 1 2 2 2 0 Mad1 and Cdc20-bound-Mad2 binding DUF342 PF03961.8 ETO25833.1 - 0.02 13.3 1.8 0.019 13.3 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DNA_primase_lrg PF04104.9 ETO25833.1 - 0.03 13.5 2.4 0.75 9.0 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit Mitofilin PF09731.4 ETO25833.1 - 0.032 12.9 9.3 0.031 12.9 6.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DBB PF14545.1 ETO25833.1 - 0.042 13.3 0.7 0.042 13.3 0.5 1.6 2 0 0 2 2 2 0 Dof, BCAP, and BANK (DBB) motif, DUF2408 PF10303.4 ETO25833.1 - 0.049 13.7 7.2 0.39 10.8 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Phage_GP20 PF06810.6 ETO25833.1 - 0.058 12.8 9.8 0.099 12.0 6.8 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 p450 PF00067.17 ETO25833.1 - 0.094 11.2 1.2 0.096 11.1 0.9 1.2 1 0 0 1 1 1 0 Cytochrome P450 PKK PF12474.3 ETO25833.1 - 0.16 11.6 11.8 1.9 8.2 7.2 2.0 2 0 0 2 2 2 0 Polo kinase kinase Phage_lysis PF03245.8 ETO25833.1 - 0.4 10.6 5.0 0.61 10.0 3.5 1.3 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein Exonuc_VII_L PF02601.10 ETO25833.1 - 0.47 9.6 8.2 0.61 9.2 5.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit IncA PF04156.9 ETO25833.1 - 0.82 9.2 7.0 1.1 8.7 4.8 1.3 1 0 0 1 1 1 0 IncA protein DUF1043 PF06295.7 ETO25833.1 - 1 9.0 8.0 1.1 8.8 4.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) Transglut_core PF01841.14 ETO25834.1 - 0.0005 20.2 0.0 0.0011 19.1 0.0 1.6 2 0 0 2 2 2 1 Transglutaminase-like superfamily DUF4635 PF15466.1 ETO25836.1 - 0.011 15.0 0.7 0.011 15.0 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) RB_A PF01858.12 ETO25836.1 - 0.042 13.5 2.0 0.053 13.1 1.2 1.3 1 1 0 1 1 1 0 Retinoblastoma-associated protein A domain SPARC_Ca_bdg PF10591.4 ETO25836.1 - 0.45 10.5 4.8 1.1 9.2 3.3 1.7 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region DUF883 PF05957.8 ETO25836.1 - 2.5 8.5 7.4 13 6.2 1.4 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) OmpH PF03938.9 ETO25836.1 - 4.8 7.0 9.6 6.4 6.6 6.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FAM195 PF14799.1 ETO25837.1 - 0.077 12.8 0.8 0.17 11.7 0.1 1.9 2 0 0 2 2 2 0 FAM195 family DUF1789 PF08748.6 ETO25837.1 - 0.099 12.7 1.6 0.31 11.1 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1789) BTB_2 PF02214.17 ETO25838.1 - 3.2e-05 24.0 0.4 0.00051 20.2 0.0 2.9 3 1 0 3 3 3 1 BTB/POZ domain PT PF04886.7 ETO25841.1 - 2.7e-29 100.1 142.4 7.7e-05 21.9 10.6 8.4 1 1 7 8 8 8 8 PT repeat FTA2 PF13095.1 ETO25841.1 - 0.041 13.4 0.1 0.12 11.9 0.1 1.8 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF912 PF06024.7 ETO25842.1 - 0.014 15.4 0.5 0.014 15.4 0.4 3.5 3 2 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) T2SF PF00482.18 ETO25842.1 - 4.8 7.0 12.4 11 5.9 8.6 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Pkinase PF00069.20 ETO25843.1 - 1.6e-36 125.7 8.5 4.8e-36 124.2 5.9 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO25843.1 - 5.4e-22 78.1 4.3 7.9e-20 71.0 3.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO25843.1 - 5.6e-05 22.2 1.9 0.0002 20.5 0.1 2.3 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO25843.1 - 0.00013 21.8 0.0 0.00032 20.4 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 ETO25843.1 - 0.0051 15.8 0.1 0.016 14.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like YukC PF10140.4 ETO25843.1 - 0.0088 14.6 0.2 0.073 11.6 0.0 2.1 1 1 1 2 2 2 1 WXG100 protein secretion system (Wss), protein YukC DUF4470 PF14737.1 ETO25843.1 - 0.017 14.8 0.3 0.046 13.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4470) DUF3724 PF12521.3 ETO25843.1 - 0.18 11.5 2.2 0.45 10.3 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3724) DUF3439 PF11921.3 ETO25843.1 - 2.3 7.9 6.6 0.41 10.3 1.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Fmp27_GFWDK PF10347.4 ETO25844.1 - 3.3e-12 46.6 0.0 6e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF843 PF05814.6 ETO25845.1 - 0.12 12.2 0.7 0.12 12.2 0.5 2.4 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) Trypan_PARP PF05887.6 ETO25846.1 - 2.8e-05 23.9 12.9 2.8e-05 23.9 8.9 3.0 4 0 0 4 4 4 1 Procyclic acidic repetitive protein (PARP) Enkurin PF13864.1 ETO25846.1 - 0.0057 16.8 10.8 0.0057 16.8 7.5 8.6 4 2 6 10 10 10 1 Calmodulin-binding SKIP_SNW PF02731.10 ETO25847.1 - 5.6e-35 120.1 2.6 5.6e-35 120.1 1.8 3.9 4 1 1 5 5 5 1 SKIP/SNW domain MIP-T3 PF10243.4 ETO25847.1 - 0.0017 16.9 21.6 0.0017 16.9 14.9 2.1 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 Mito_carr PF00153.22 ETO25848.1 - 1.1e-05 25.0 0.0 2.1e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial carrier protein SNF2_N PF00176.18 ETO25849.1 - 3.7e-21 75.2 0.1 7.8e-21 74.1 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Ras PF00071.17 ETO25850.1 - 1.2e-05 24.7 0.7 0.015 14.7 0.1 2.2 2 0 0 2 2 2 2 Ras family NMT_C PF02799.10 ETO25851.1 - 0.12 11.7 5.2 0.16 11.3 3.6 1.2 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain DUF2393 PF09624.5 ETO25851.1 - 0.31 10.5 8.8 0.13 11.7 4.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2393) U-box PF04564.10 ETO25851.1 - 2.2 8.3 5.5 2.3 8.2 2.1 2.1 2 1 0 2 2 2 0 U-box domain DMAP1 PF05499.7 ETO25851.1 - 4.8 6.6 20.9 0.2 11.1 5.4 2.1 1 1 1 2 2 2 0 DNA methyltransferase 1-associated protein 1 (DMAP1) DUF604 PF04646.7 ETO25851.1 - 5.1 6.2 6.8 8.9 5.4 4.7 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF604 DUF960 PF06124.6 ETO25851.1 - 8 6.7 9.9 5.5 7.3 1.8 2.1 1 1 0 2 2 2 0 Staphylococcal protein of unknown function (DUF960) WD40 PF00400.27 ETO25853.1 - 8.1e-11 41.3 1.7 0.00021 21.0 0.0 3.5 4 0 0 4 4 4 2 WD domain, G-beta repeat eIF2A PF08662.6 ETO25853.1 - 0.0015 18.2 0.1 0.013 15.2 0.0 2.4 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A CPSF_A PF03178.10 ETO25853.1 - 0.0061 15.6 0.2 0.014 14.5 0.2 1.6 1 0 0 1 1 1 1 CPSF A subunit region Eapp_C PF10238.4 ETO25853.1 - 0.023 14.6 0.6 0.059 13.2 0.1 1.9 2 0 0 2 2 2 0 E2F-associated phosphoprotein Yeast-kill-tox PF09207.6 ETO25853.1 - 0.039 14.3 0.1 12 6.3 0.0 2.6 2 0 0 2 2 2 0 Yeast killer toxin YMF19 PF02326.10 ETO25854.1 - 0.02 15.4 1.8 0.02 15.4 1.2 3.6 3 1 1 4 4 4 0 Plant ATP synthase F0 Sec63 PF02889.11 ETO25856.1 - 4.2e-79 266.0 0.3 5.7e-79 265.5 0.2 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 ETO25856.1 - 3.7e-36 124.1 0.4 8.8e-24 83.8 0.0 3.3 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 ETO25856.1 - 2.5e-09 37.2 0.2 4.3e-06 26.6 0.0 2.7 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 ETO25856.1 - 7.4e-06 25.7 0.0 2.9e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 ETO25856.1 - 0.00017 21.7 0.5 0.16 12.1 0.0 3.0 2 1 0 2 2 2 2 AAA domain T2SE PF00437.15 ETO25856.1 - 0.069 12.0 0.0 0.16 10.8 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.24 ETO25856.1 - 0.071 13.3 0.2 3 8.0 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PAS_8 PF13188.1 ETO25856.1 - 0.15 11.9 0.4 5.3 7.0 0.0 3.1 3 0 0 3 3 3 0 PAS domain HEAT PF02985.17 ETO25857.1 - 4.5e-07 29.4 4.3 0.33 11.1 0.0 5.8 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 ETO25857.1 - 1.2e-06 28.7 0.2 0.18 12.1 0.1 4.6 3 2 1 4 4 4 1 HEAT repeats HEAT_EZ PF13513.1 ETO25857.1 - 1.1e-05 25.7 1.4 0.037 14.5 0.0 5.6 5 1 1 6 6 5 2 HEAT-like repeat Nop14 PF04147.7 ETO25857.1 - 6.6e-05 21.0 8.4 6.6e-05 21.0 5.8 2.1 2 0 0 2 2 2 1 Nop14-like family Tom22 PF04281.8 ETO25857.1 - 0.0018 17.8 1.4 0.0018 17.8 0.9 2.8 2 0 0 2 2 2 1 Mitochondrial import receptor subunit Tom22 GCIP PF13324.1 ETO25857.1 - 0.0022 17.2 13.1 0.48 9.6 0.4 3.6 3 0 0 3 3 3 2 Grap2 and cyclin-D-interacting FimP PF09766.4 ETO25857.1 - 0.016 14.2 22.4 0.25 10.3 2.6 2.2 2 0 0 2 2 2 0 Fms-interacting protein RRN3 PF05327.6 ETO25857.1 - 0.019 13.1 14.3 0.021 12.9 3.3 2.6 3 0 0 3 3 3 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4484 PF14831.1 ETO25857.1 - 0.046 13.8 0.7 0.046 13.8 0.5 3.3 2 1 1 3 3 2 0 Domain of unknown function (DUF4484) CDC45 PF02724.9 ETO25857.1 - 0.087 10.8 22.3 0.0044 15.1 3.6 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF3357 PF11837.3 ETO25857.1 - 0.087 12.6 0.2 0.087 12.6 0.1 3.2 3 1 0 3 3 1 0 Domain of unknown function (DUF3357) Pox_Ag35 PF03286.9 ETO25857.1 - 0.12 11.9 19.0 0.062 12.8 5.0 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Sigma70_ner PF04546.8 ETO25857.1 - 0.12 12.0 19.7 0.14 11.7 4.8 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region POX PF07526.6 ETO25857.1 - 0.27 11.4 14.8 1.8 8.7 3.3 2.8 2 1 0 2 2 2 0 Associated with HOX Pex14_N PF04695.8 ETO25857.1 - 0.35 10.8 5.3 2.1 8.4 0.5 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region BUD22 PF09073.5 ETO25857.1 - 0.36 9.8 22.0 1.2 8.0 6.8 2.3 2 0 0 2 2 2 0 BUD22 DUF2722 PF10846.3 ETO25857.1 - 0.57 9.1 18.0 0.92 8.4 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) BTV_NS2 PF04514.7 ETO25857.1 - 0.66 8.7 16.5 1.4 7.6 3.4 2.4 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 TRAP_alpha PF03896.11 ETO25857.1 - 1.4 7.8 18.3 3.4 6.5 5.7 2.6 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Gti1_Pac2 PF09729.4 ETO25857.1 - 1.5 8.6 6.7 14 5.5 2.2 2.3 2 0 0 2 2 2 0 Gti1/Pac2 family DDHD PF02862.12 ETO25857.1 - 1.5 8.5 10.9 2.6 7.7 0.5 2.8 3 0 0 3 3 3 0 DDHD domain SDA1 PF05285.7 ETO25857.1 - 3 7.0 26.8 1.6 7.9 8.7 2.4 2 0 0 2 2 2 0 SDA1 Spore_coat_CotO PF14153.1 ETO25857.1 - 5.9 6.2 17.6 0.61 9.5 1.7 2.6 3 0 0 3 3 3 0 Spore coat protein CotO zf-C2H2 PF00096.21 ETO25858.1 - 3e-13 49.2 28.8 1.8e-06 27.9 0.3 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETO25858.1 - 9.5e-11 41.4 32.0 0.002 18.3 2.0 4.7 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 ETO25858.1 - 1e-09 38.0 26.3 6.4e-06 26.1 0.1 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 ETO25858.1 - 1.2e-05 25.2 19.8 0.00023 21.2 0.9 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 ETO25858.1 - 1.5e-05 24.9 5.5 0.0011 19.1 0.4 3.6 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-BED PF02892.10 ETO25858.1 - 0.013 15.2 3.3 0.013 15.2 2.3 3.9 2 1 2 4 4 4 0 BED zinc finger Zn-ribbon_8 PF09723.5 ETO25858.1 - 0.14 12.1 0.3 0.14 12.1 0.2 3.6 3 1 0 3 3 3 0 Zinc ribbon domain zf-C2HC_2 PF13913.1 ETO25858.1 - 0.17 11.5 0.5 0.17 11.5 0.3 4.2 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.1 ETO25858.1 - 0.21 11.5 0.3 0.21 11.5 0.2 4.3 5 0 0 5 5 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 ETO25858.1 - 0.3 11.2 18.5 0.25 11.4 1.7 3.1 1 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) ROS_MUCR PF05443.6 ETO25858.1 - 0.47 10.2 3.8 0.17 11.6 0.8 1.6 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein DUF2296 PF10058.4 ETO25858.1 - 0.48 10.2 4.0 4.9 6.9 0.1 2.9 3 0 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) HNH_5 PF14279.1 ETO25858.1 - 0.99 9.4 8.1 0.54 10.2 1.5 2.4 2 0 0 2 2 2 0 HNH endonuclease Prok-RING_1 PF14446.1 ETO25858.1 - 1.2 8.8 9.8 1.3 8.8 0.2 3.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-U11-48K PF05253.7 ETO25858.1 - 3.2 7.5 8.4 8.8 6.1 0.4 4.2 4 0 0 4 4 4 0 U11-48K-like CHHC zinc finger Ribosomal_L37ae PF01780.14 ETO25858.1 - 5.3 6.9 9.9 5.3 6.9 0.5 3.1 2 1 0 2 2 2 0 Ribosomal L37ae protein family XPA_N PF01286.13 ETO25858.1 - 6.2 6.5 20.1 1.9 8.2 0.6 3.8 3 1 1 4 4 4 0 XPA protein N-terminal zf-Di19 PF05605.7 ETO25858.1 - 9.6 6.4 23.1 0.38 10.9 4.5 3.6 1 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding TPR_11 PF13414.1 ETO25859.1 - 1e-06 28.2 0.5 5.6e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 TPR repeat Porph_ging PF09697.5 ETO25859.1 - 1 9.5 3.8 0.63 10.2 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (Porph_ging) EF-hand_1 PF00036.27 ETO25860.1 - 6e-25 84.5 11.0 3.6e-07 29.0 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 ETO25860.1 - 5.7e-23 80.8 10.5 8.8e-13 48.1 1.9 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO25860.1 - 2.3e-21 73.7 7.8 2.5e-05 23.7 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 ETO25860.1 - 1.8e-16 58.6 9.7 4e-05 22.7 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 ETO25860.1 - 4.8e-12 45.2 14.0 4.2e-06 26.2 0.5 3.5 1 1 2 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 ETO25860.1 - 0.00047 20.1 4.7 0.11 12.5 0.0 3.4 3 0 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 ETO25860.1 - 0.11 12.2 5.5 8.7 6.0 0.0 4.2 3 1 1 4 4 4 0 EF hand EF-hand_4 PF12763.2 ETO25860.1 - 0.13 11.9 6.6 6.1 6.6 0.7 3.3 1 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand RP-C_C PF11800.3 ETO25860.1 - 0.8 9.3 3.6 1.5 8.4 2.5 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region NuA4 PF09340.5 ETO25861.1 - 0.94 9.1 4.0 1.7 8.3 0.5 2.4 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 RabGAP-TBC PF00566.13 ETO25862.1 - 4.1e-48 163.6 4.9 3.9e-41 140.8 1.9 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Cullin_binding PF03556.10 ETO25862.1 - 0.071 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Cullin binding HEAT_EZ PF13513.1 ETO25863.1 - 1e-05 25.8 3.0 0.43 11.1 0.0 5.1 3 3 2 5 5 5 4 HEAT-like repeat zf-RING_2 PF13639.1 ETO25864.1 - 0.45 10.3 8.5 0.081 12.7 2.1 2.6 2 1 0 2 2 2 0 Ring finger domain Proteasom_Rpn13 PF04683.8 ETO25866.1 - 2.9e-12 46.4 0.1 8.9e-12 44.9 0.0 1.9 2 0 0 2 2 2 1 Proteasome complex subunit Rpn13 ubiquitin receptor DMA PF03474.9 ETO25866.1 - 0.015 15.1 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 DMRTA motif HTH_8 PF02954.14 ETO25866.1 - 0.13 11.8 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Acetyltransf_1 PF00583.19 ETO25867.1 - 1.2e-06 28.4 0.2 1.1e-05 25.3 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETO25867.1 - 0.0026 17.8 0.2 0.097 12.8 0.0 2.5 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETO25867.1 - 0.015 15.0 0.0 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_9 PF13527.1 ETO25867.1 - 0.028 14.2 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MRP-S26 PF14943.1 ETO25867.1 - 0.052 13.0 5.2 0.082 12.4 3.6 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Acetyltransf_10 PF13673.1 ETO25867.1 - 0.067 13.3 0.0 0.27 11.3 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF2116 PF09889.4 ETO25869.1 - 0.031 14.0 1.7 0.049 13.4 0.3 2.0 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) YfhD PF14151.1 ETO25869.1 - 0.079 13.0 1.5 0.095 12.8 0.0 1.8 2 0 0 2 2 2 0 YfhD-like protein SH3_3 PF08239.6 ETO25870.1 - 0.03 14.4 0.0 0.42 10.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial SH3 domain Neur_chan_memb PF02932.11 ETO25870.1 - 2.6 7.8 6.6 0.69 9.7 2.3 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region zf-rbx1 PF12678.2 ETO25871.1 - 0.14 12.2 14.5 0.044 13.9 6.9 2.3 2 1 1 3 3 3 0 RING-H2 zinc finger C1_1 PF00130.17 ETO25871.1 - 0.36 10.5 12.2 0.035 13.8 4.5 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) WD40 PF00400.27 ETO25872.1 - 1.5e-13 50.0 17.9 7e-08 32.0 0.0 6.0 6 2 0 6 6 6 2 WD domain, G-beta repeat Cu-oxidase_2 PF07731.9 ETO25873.1 - 0.0097 15.4 0.3 0.35 10.3 0.1 2.2 2 0 0 2 2 2 2 Multicopper oxidase AAA_33 PF13671.1 ETO25874.1 - 2.9e-09 36.9 0.2 8.1e-09 35.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ETO25874.1 - 1.8e-08 35.2 0.0 2.8e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETO25874.1 - 5.9e-07 29.8 0.9 1.2e-06 28.8 0.0 2.0 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 ETO25874.1 - 1.2e-05 24.6 0.0 2.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_22 PF13401.1 ETO25874.1 - 9e-05 22.6 0.2 0.00027 21.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETO25874.1 - 0.00023 20.8 0.0 0.00039 20.1 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 ETO25874.1 - 0.00047 20.1 0.1 0.00087 19.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETO25874.1 - 0.00068 19.6 0.0 0.001 19.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 ETO25874.1 - 0.00085 18.4 0.2 0.00085 18.4 0.2 2.1 2 1 0 2 2 2 1 Zeta toxin AAA_14 PF13173.1 ETO25874.1 - 0.0031 17.4 0.0 0.0051 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 ETO25874.1 - 0.0039 16.8 0.0 0.0065 16.1 0.0 1.3 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 ETO25874.1 - 0.0062 15.4 0.0 0.01 14.6 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Viral_helicase1 PF01443.13 ETO25874.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 ETO25874.1 - 0.012 15.2 0.3 0.039 13.5 0.1 1.9 2 1 1 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 ETO25874.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 ETO25874.1 - 0.024 14.0 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 ETO25874.1 - 0.03 13.7 0.0 0.057 12.8 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_5 PF07728.9 ETO25874.1 - 0.035 13.8 0.2 0.082 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) 6PF2K PF01591.13 ETO25874.1 - 0.046 12.7 0.0 0.097 11.7 0.0 1.5 1 0 0 1 1 1 0 6-phosphofructo-2-kinase ADK PF00406.17 ETO25874.1 - 0.054 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Adenylate kinase AAA_25 PF13481.1 ETO25874.1 - 0.092 12.1 0.2 0.67 9.3 0.1 2.1 1 1 0 2 2 2 0 AAA domain RuvB_N PF05496.7 ETO25874.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus T2SE PF00437.15 ETO25874.1 - 0.14 11.0 0.0 0.42 9.4 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein EF-hand_6 PF13405.1 ETO25875.1 - 0.0016 18.1 0.0 0.015 15.1 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain OST-HTH PF12872.2 ETO25875.1 - 0.092 12.6 0.0 0.32 10.8 0.0 1.9 1 0 0 1 1 1 0 OST-HTH/LOTUS domain Pkinase PF00069.20 ETO25876.1 - 2.1e-08 33.6 0.1 4.8e-08 32.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO25876.1 - 0.0025 16.9 0.0 0.0047 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase zf-RING_2 PF13639.1 ETO25877.1 - 1.4e-10 40.7 11.5 1.4e-10 40.7 8.0 1.7 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 ETO25877.1 - 7.7e-07 29.1 10.2 7.7e-07 29.1 7.1 2.3 3 0 0 3 3 3 1 RING-H2 zinc finger zf-Apc11 PF12861.2 ETO25877.1 - 1.3e-05 24.9 6.3 1.3e-05 24.9 4.4 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 ETO25877.1 - 0.00012 21.6 11.3 0.00012 21.6 7.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO25877.1 - 0.00037 20.1 13.0 0.00037 20.1 9.0 1.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 ETO25877.1 - 0.0011 18.5 15.1 0.0011 18.5 10.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO25877.1 - 0.0044 17.0 13.8 0.0044 17.0 9.6 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 ETO25877.1 - 0.056 13.1 10.3 0.12 12.1 7.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger RINGv PF12906.2 ETO25877.1 - 0.06 13.4 13.4 0.12 12.3 9.3 1.6 1 0 0 1 1 1 0 RING-variant domain Baculo_RING PF05883.6 ETO25877.1 - 0.5 10.2 10.2 2.9 7.7 7.0 2.3 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-C3HC4_4 PF15227.1 ETO25877.1 - 3.1 7.7 9.3 19 5.2 6.5 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 ETO25877.1 - 4.3 7.3 12.5 19 5.3 8.6 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 ETO25877.1 - 8.5 6.0 9.5 32 4.1 6.6 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Peptidase_C14 PF00656.17 ETO25878.1 - 2.6e-13 50.2 0.6 5.5e-13 49.1 0.4 1.5 1 0 0 1 1 1 1 Caspase domain DUF772 PF05598.6 ETO25878.1 - 0.04 13.8 3.0 1 9.3 0.1 2.7 3 0 0 3 3 3 0 Transposase domain (DUF772) MULE PF10551.4 ETO25878.1 - 0.27 11.4 1.5 13 6.0 0.0 3.3 3 0 0 3 3 3 0 MULE transposase domain HHV6-IE PF03753.8 ETO25879.1 - 0.032 11.7 9.1 0.041 11.3 6.3 1.0 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein Aminotran_4 PF01063.14 ETO25879.1 - 0.069 12.6 0.1 0.081 12.3 0.1 1.2 1 0 0 1 1 1 0 Aminotransferase class IV DUF2868 PF11067.3 ETO25879.1 - 4.7 6.2 6.3 6 5.9 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) DUF3597 PF12200.3 ETO25879.1 - 8.6 6.7 9.0 0.65 10.3 1.3 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF3597) PIN_4 PF13638.1 ETO25880.1 - 0.029 14.4 0.3 0.29 11.2 0.0 2.5 2 0 0 2 2 2 0 PIN domain DUF2457 PF10446.4 ETO25882.1 - 6.1 5.4 8.2 7.6 5.1 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF3487 PF11990.3 ETO25883.1 - 0.026 13.9 0.5 0.052 12.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) Flavi_M PF01004.14 ETO25883.1 - 0.93 8.9 3.8 7.6 6.0 0.1 2.5 1 1 1 2 2 2 0 Flavivirus envelope glycoprotein M Pol_alpha_B_N PF08418.5 ETO25884.1 - 6 6.3 9.3 11 5.4 6.4 1.8 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Ribosomal_S3_C PF00189.15 ETO25885.1 - 2.4e-10 40.4 0.4 6.6e-09 35.8 0.3 2.6 1 1 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 ETO25885.1 - 1.1e-09 37.7 0.2 2.2e-09 36.7 0.2 1.6 1 0 0 1 1 1 1 KH domain Phage_Mu_Gam PF07352.7 ETO25885.1 - 0.074 12.5 0.3 0.26 10.8 0.0 2.0 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein CFIA_Pcf11 PF11526.3 ETO25886.1 - 0.02 15.0 1.3 0.02 15.0 0.9 3.7 2 2 0 3 3 3 0 Subunit of cleavage factor IA Pcf11 bHLH-MYC_N PF14215.1 ETO25886.1 - 1.1 9.4 4.4 0.19 11.9 0.5 1.7 2 0 0 2 2 2 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal Ribosomal_S21 PF01165.15 ETO25887.1 - 0.018 14.4 0.1 0.079 12.4 0.1 1.9 2 0 0 2 2 2 0 Ribosomal protein S21 DUF3821 PF12863.2 ETO25890.1 - 0.051 13.2 0.7 0.06 13.0 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3821) IL8 PF00048.15 ETO25890.1 - 0.094 12.6 0.1 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Small cytokines (intecrine/chemokine), interleukin-8 like zf-RanBP PF00641.13 ETO25891.1 - 2.9e-07 29.4 3.1 1.4e-06 27.2 2.1 2.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others SprA-related PF12118.3 ETO25891.1 - 0.31 10.3 13.8 0.38 10.0 9.6 1.1 1 0 0 1 1 1 0 SprA-related family Macoilin PF09726.4 ETO25891.1 - 0.48 8.6 12.3 0.53 8.5 8.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Raftlin PF15250.1 ETO25891.1 - 3.1 6.2 12.6 4.3 5.7 8.7 1.1 1 0 0 1 1 1 0 Raftlin Ndc1_Nup PF09531.5 ETO25891.1 - 3.2 6.0 12.4 5.2 5.3 8.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup IQ PF00612.22 ETO25892.1 - 8.1e-08 31.2 16.9 0.0015 17.9 0.5 4.2 4 0 0 4 4 4 3 IQ calmodulin-binding motif Pyridox_oxidase PF01243.15 ETO25893.1 - 0.072 13.1 0.0 0.17 11.9 0.0 1.8 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase DiS_P_DiS PF06750.8 ETO25893.1 - 0.29 10.9 2.5 4.9 7.0 0.1 2.4 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain LMBR1 PF04791.11 ETO25894.1 - 0.00011 20.8 0.1 0.0012 17.4 0.0 2.1 1 1 1 2 2 2 1 LMBR1-like membrane protein DUF4599 PF15371.1 ETO25894.1 - 0.044 13.8 0.2 0.044 13.8 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4599) SH3_1 PF00018.23 ETO25895.1 - 2.9e-14 52.1 0.1 5e-14 51.4 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 ETO25895.1 - 3.3e-13 48.9 0.1 5.8e-13 48.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 ETO25895.1 - 1.2e-11 43.8 0.2 2.2e-11 43.0 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain HC2 PF07382.6 ETO25895.1 - 2.9 7.7 15.9 3.4 7.5 11.1 1.3 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Mucin PF01456.12 ETO25895.1 - 8.6 6.1 10.0 0.99 9.1 3.9 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein Ferric_reduct PF01794.14 ETO25896.1 - 1.1e-15 57.8 6.6 1.1e-15 57.8 4.6 1.7 2 0 0 2 2 2 1 Ferric reductase like transmembrane component N6_N4_Mtase PF01555.13 ETO25896.1 - 0.016 14.7 0.4 0.025 14.0 0.3 1.3 1 0 0 1 1 1 0 DNA methylase Baculo_11_kDa PF06143.6 ETO25896.1 - 0.1 11.9 0.2 2.3 7.6 0.1 2.7 2 0 0 2 2 2 0 Baculovirus 11 kDa family ATP-gua_Ptrans PF00217.14 ETO25899.1 - 1.6e-09 37.4 0.6 2.5e-07 30.2 0.0 2.1 2 0 0 2 2 2 2 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 ETO25900.1 - 4e-20 71.7 0.0 4e-20 71.7 0.0 2.2 3 0 0 3 3 3 1 ATP:guanido phosphotransferase, N-terminal domain ATP-gua_Ptrans PF00217.14 ETO25900.1 - 2.1e-12 46.8 2.4 3.8e-06 26.4 0.0 2.4 2 1 0 2 2 2 2 ATP:guanido phosphotransferase, C-terminal catalytic domain DUF4551 PF15087.1 ETO25900.1 - 1.6 6.9 14.9 2.3 6.4 10.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SPARC_Ca_bdg PF10591.4 ETO25900.1 - 4.8 7.2 7.1 0.19 11.7 0.2 2.2 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Swi3 PF07962.7 ETO25901.1 - 0.063 12.9 0.0 0.67 9.6 0.0 2.5 2 0 0 2 2 2 0 Replication Fork Protection Component Swi3 HAUS6_N PF14661.1 ETO25902.1 - 5 6.4 17.0 0.027 13.8 4.4 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus WD40 PF00400.27 ETO25903.1 - 5.6e-61 200.4 25.2 1.7e-10 40.3 1.2 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO25903.1 - 7.4e-13 47.4 1.3 0.011 13.8 0.1 5.7 3 1 2 6 6 6 4 Nucleoporin Nup120/160 Kazal_1 PF00050.16 ETO25903.1 - 0.075 13.0 0.0 0.25 11.3 0.0 1.9 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain YfhO PF09586.5 ETO25903.1 - 1.2 7.0 13.5 1.7 6.5 9.4 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO 4HBT PF03061.17 ETO25904.1 - 1.2e-09 38.1 0.1 2.3e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily DUF730 PF05325.6 ETO25905.1 - 0.042 13.6 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF730) Anoctamin PF04547.7 ETO25906.1 - 3.6e-92 309.3 11.0 1.6e-89 300.6 7.6 2.2 1 1 0 1 1 1 1 Calcium-activated chloride channel UPF0118 PF01594.11 ETO25906.1 - 0.0075 15.3 0.0 0.0075 15.3 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function DUF20 SAM_1 PF00536.25 ETO25906.1 - 0.016 15.3 0.1 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) FF PF01846.14 ETO25908.1 - 2.1e-12 46.7 13.3 2.3e-09 37.0 0.1 4.5 3 1 1 4 4 4 2 FF domain Bcl-2 PF00452.14 ETO25908.1 - 0.25 11.5 4.1 0.15 12.1 1.2 2.0 2 1 0 2 2 2 0 Apoptosis regulator proteins, Bcl-2 family CmcH_NodU PF02543.10 ETO25908.1 - 0.38 9.8 6.5 0.066 12.3 1.9 1.6 2 0 0 2 2 2 0 Carbamoyltransferase Rotamase PF00639.16 ETO25908.1 - 0.76 10.5 10.5 6.4 7.5 0.3 3.2 3 0 0 3 3 3 0 PPIC-type PPIASE domain DUF3573 PF12097.3 ETO25908.1 - 0.81 8.2 4.1 1.1 7.7 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF664 PF04978.7 ETO25908.1 - 1.6 8.9 5.5 10 6.3 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF664) DUF4326 PF14216.1 ETO25908.1 - 5.3 7.6 7.4 4.5 7.9 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4326) YMF19 PF02326.10 ETO25908.1 - 9.4 6.8 12.9 0.85 10.2 2.2 3.1 2 1 0 3 3 3 0 Plant ATP synthase F0 UBA PF00627.26 ETO25909.1 - 4.3e-08 32.7 0.2 8.4e-08 31.8 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain DUF826 PF05696.6 ETO25909.1 - 0.52 10.4 2.3 0.32 11.1 0.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF826) KLRAQ PF10205.4 ETO25909.1 - 1.9 8.5 6.9 11 6.1 2.6 2.6 1 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein XPC-binding PF09280.6 ETO25910.1 - 0.026 13.9 16.4 6 6.3 5.3 3.4 1 1 1 2 2 2 0 XPC-binding domain SpoIIE PF07228.7 ETO25911.1 - 0.014 15.0 0.0 0.31 10.7 0.0 2.1 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) AAA PF00004.24 ETO25912.1 - 8e-05 22.8 0.1 0.0003 20.9 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 ETO25912.1 - 0.00023 21.4 0.0 0.0011 19.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ETO25912.1 - 0.0013 19.5 0.0 0.003 18.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETO25912.1 - 0.0074 16.4 0.1 0.016 15.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 ETO25912.1 - 0.024 14.1 0.1 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 ETO25912.1 - 0.028 14.4 0.2 0.24 11.3 0.0 2.3 2 1 1 3 3 3 0 AAA ATPase domain AAA_11 PF13086.1 ETO25912.1 - 0.032 13.7 0.1 0.054 13.0 0.0 1.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 ETO25912.1 - 0.035 13.8 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 ETO25912.1 - 0.04 13.5 0.8 0.14 11.8 0.0 2.1 2 1 0 2 2 2 0 NACHT domain NB-ARC PF00931.17 ETO25912.1 - 0.063 12.1 0.0 0.097 11.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 ETO25912.1 - 0.063 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 ETO25912.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 ETO25912.1 - 0.12 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.7 ETO25912.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.24 ETO25913.1 - 3.1e-07 30.6 0.0 6.4e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETO25913.1 - 0.0086 16.2 0.1 0.026 14.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain MCM_N PF14551.1 ETO25913.1 - 0.0096 16.4 0.1 0.083 13.3 0.1 2.4 1 1 0 1 1 1 1 MCM N-terminal domain YcbB PF08664.5 ETO25913.1 - 0.063 13.0 0.1 0.29 10.9 0.0 2.1 1 1 1 2 2 2 0 YcbB domain DUF4014 PF13198.1 ETO25913.1 - 0.44 10.9 4.0 1.5 9.2 2.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4014) Glyco_hydro_18 PF00704.23 ETO25914.1 - 3.5e-06 26.7 0.1 5.4e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 WD40 PF00400.27 ETO25915.1 - 1.6e-73 240.2 31.8 6.6e-12 44.8 0.0 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO25915.1 - 4.9e-13 49.2 1.6 7.9e-09 35.4 0.0 3.5 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Tox-PL PF15644.1 ETO25915.1 - 1.6e-06 28.7 0.3 2.5 8.8 0.0 4.3 4 0 0 4 4 4 2 Papain fold toxin 1 Nup160 PF11715.3 ETO25915.1 - 8.2e-06 24.2 14.3 0.059 11.5 0.4 5.0 1 1 3 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO25915.1 - 8.4e-06 24.7 12.7 0.29 9.8 0.4 4.7 1 1 3 4 4 4 3 Nup133 N terminal like Coatomer_WDAD PF04053.9 ETO25915.1 - 0.00053 18.8 3.0 0.0044 15.8 1.8 2.3 1 1 1 2 2 2 1 Coatomer WD associated region Cytochrom_D1 PF02239.11 ETO25915.1 - 0.00083 17.7 1.5 0.071 11.4 0.2 3.1 1 1 4 5 5 5 2 Cytochrome D1 heme domain IKI3 PF04762.7 ETO25915.1 - 0.0031 15.4 2.1 0.08 10.7 0.1 2.1 1 1 1 2 2 2 2 IKI3 family DUF4072 PF13284.1 ETO25915.1 - 0.0053 16.9 0.0 9.5 6.4 0.0 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF4072) Nbas_N PF15492.1 ETO25915.1 - 0.0059 15.7 2.6 0.52 9.3 0.1 3.2 1 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Hira PF07569.6 ETO25915.1 - 0.0097 15.1 3.6 18 4.4 0.0 4.2 2 2 2 4 4 4 0 TUP1-like enhancer of split DUF727 PF05303.7 ETO25915.1 - 0.11 12.2 1.1 3 7.6 0.0 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF727) DUF1914 PF08932.5 ETO25915.1 - 4.1 7.4 7.9 11 6.0 0.1 3.9 2 1 3 5 5 5 0 Domain of unknown function (DUF1914) WD40 PF00400.27 ETO25916.1 - 3.4e-60 197.8 7.3 2.4e-11 43.0 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO25916.1 - 5.7e-13 49.0 0.2 1.4e-05 24.9 0.0 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO25916.1 - 2.8e-06 25.8 0.9 0.37 9.0 0.2 3.6 2 1 1 3 3 3 3 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO25916.1 - 3.8e-06 26.5 1.0 1.2e-05 24.9 0.7 1.6 1 1 0 1 1 1 1 PQQ-like domain Nup160 PF11715.3 ETO25916.1 - 7.4e-06 24.3 3.2 0.012 13.7 1.2 3.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PD40 PF07676.7 ETO25916.1 - 2.8e-05 23.6 2.1 18 5.0 0.0 6.0 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 ETO25916.1 - 0.00027 19.6 0.2 0.25 9.9 0.1 3.6 2 1 2 4 4 4 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nucleoporin_N PF08801.6 ETO25916.1 - 0.0025 16.6 7.2 0.15 10.7 0.3 3.7 1 1 3 4 4 4 2 Nup133 N terminal like Str_synth PF03088.11 ETO25916.1 - 0.009 16.0 0.1 1.7 8.7 0.0 3.0 3 0 0 3 3 3 1 Strictosidine synthase PQQ PF01011.16 ETO25916.1 - 0.011 15.1 0.0 15 5.3 0.0 3.9 4 0 0 4 4 4 0 PQQ enzyme repeat Resistin PF06954.6 ETO25916.1 - 0.034 14.4 0.2 9.1 6.6 0.0 3.0 2 1 1 3 3 3 0 Resistin OapA PF04225.7 ETO25916.1 - 0.039 13.8 0.9 3.3 7.6 0.1 3.4 2 1 3 5 5 5 0 Opacity-associated protein A LysM-like domain DUF3832 PF12909.2 ETO25916.1 - 0.043 13.8 0.2 0.18 11.8 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3832) DUF281 PF03436.8 ETO25916.1 - 2.1 8.4 4.4 28 4.8 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF281) Gelsolin PF00626.17 ETO25917.1 - 0.025 14.2 0.1 0.061 13.0 0.1 1.6 1 0 0 1 1 1 0 Gelsolin repeat NIF PF03031.13 ETO25918.1 - 3e-25 88.7 0.4 7.7e-25 87.4 0.3 1.7 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.21 ETO25918.1 - 4.3e-10 39.6 0.6 1.1e-09 38.3 0.1 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 ETO25918.1 - 1.8e-06 27.7 0.4 4.3e-06 26.5 0.2 1.7 1 0 0 1 1 1 1 twin BRCT domain Biotin_lipoyl_2 PF13533.1 ETO25918.1 - 9.8e-05 21.9 0.1 0.00023 20.7 0.0 1.5 1 0 0 1 1 1 1 Biotin-lipoyl like Biotin_lipoyl PF00364.17 ETO25918.1 - 0.005 16.4 0.1 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme TPR_11 PF13414.1 ETO25920.1 - 0.37 10.4 5.0 5.4 6.7 1.3 3.1 3 0 0 3 3 3 0 TPR repeat BUD22 PF09073.5 ETO25921.1 - 1.5 7.8 11.8 1.8 7.5 8.2 1.0 1 0 0 1 1 1 0 BUD22 HATPase_c PF02518.21 ETO25922.1 - 1.8e-14 53.4 0.0 2.9e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BCDHK_Adom3 PF10436.4 ETO25922.1 - 2.6e-14 53.0 0.0 1.7e-13 50.4 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c_3 PF13589.1 ETO25922.1 - 0.00018 21.1 0.0 0.00033 20.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WD40 PF00400.27 ETO25923.1 - 8.7e-11 41.2 0.2 8.8e-10 38.0 0.0 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat NACHT PF05729.7 ETO25923.1 - 1.6e-09 37.6 0.0 3e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO25923.1 - 8.6e-06 26.0 0.2 8.6e-06 26.0 0.1 3.4 2 2 1 3 3 3 1 AAA domain AAA_17 PF13207.1 ETO25923.1 - 0.00044 21.0 6.3 0.00063 20.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETO25923.1 - 0.0023 18.0 0.0 0.0066 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF809 PF05663.6 ETO25923.1 - 0.052 13.4 4.1 0.098 12.5 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF809) AAA PF00004.24 ETO25923.1 - 0.058 13.5 0.1 0.28 11.3 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Pentapeptide_3 PF13576.1 ETO25923.1 - 0.27 11.1 5.1 0.84 9.5 3.5 1.7 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) Arf PF00025.16 ETO25924.1 - 1.3e-20 73.3 0.0 1.4e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 ETO25924.1 - 5.6e-08 31.8 1.0 0.00022 20.0 0.1 2.0 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 ETO25924.1 - 1.1e-05 25.3 0.0 1.2e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 ETO25924.1 - 9.7e-05 21.8 0.0 0.00012 21.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 ETO25924.1 - 0.0024 17.0 0.0 0.0027 16.8 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 ETO25924.1 - 0.0061 15.8 0.0 0.0069 15.6 0.0 1.1 1 0 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 ETO25924.1 - 0.012 14.7 0.0 0.015 14.5 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.13 ETO25924.1 - 0.023 13.7 0.0 0.024 13.6 0.0 1.1 1 0 0 1 1 1 0 Septin AAA_29 PF13555.1 ETO25924.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arf PF00025.16 ETO25925.1 - 6.7e-16 58.0 0.1 1.1e-15 57.3 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SnoaL_2 PF12680.2 ETO25926.1 - 0.019 15.3 0.0 0.031 14.6 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain DUF3584 PF12128.3 ETO25927.1 - 1.5 6.0 3.6 1.9 5.6 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Mito_carr PF00153.22 ETO25929.1 - 5.2e-46 154.2 0.7 1.1e-18 66.7 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3905 PF13045.1 ETO25929.1 - 0.02 14.6 0.4 0.041 13.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3905) RhoGAP PF00620.22 ETO25930.1 - 6.9e-20 71.1 0.2 9.1e-20 70.8 0.1 1.2 1 0 0 1 1 1 1 RhoGAP domain CCDC-167 PF15188.1 ETO25930.1 - 0.0028 17.5 1.3 0.004 17.0 0.9 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 Pox_L5 PF04872.8 ETO25930.1 - 0.057 13.0 0.3 0.26 10.9 0.0 2.2 2 1 1 3 3 3 0 Poxvirus L5 protein family DUF1958 PF09211.5 ETO25930.1 - 0.073 13.1 0.8 0.21 11.7 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1958) FKBP_N PF01346.13 ETO25930.1 - 0.088 12.8 0.1 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase zf-C2H2_6 PF13912.1 ETO25931.1 - 2.4e-06 27.2 0.2 8.7e-06 25.4 0.1 2.0 1 0 0 1 1 1 1 C2H2-type zinc finger FYDLN_acid PF09538.5 ETO25931.1 - 5.1 7.7 14.7 5.6 7.6 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) Mucin PF01456.12 ETO25931.1 - 9.4 6.0 31.0 5.9 6.6 16.0 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF2594 PF10769.4 ETO25932.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2594) DUF3746 PF12562.3 ETO25933.1 - 0.33 10.8 4.9 0.95 9.3 0.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3746) AAA PF00004.24 ETO25934.1 - 1.1e-13 51.4 0.0 1.6e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETO25934.1 - 1.1e-08 35.2 0.0 0.00051 20.0 0.0 2.3 1 1 1 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 ETO25934.1 - 6.3e-06 26.3 0.0 1.6e-05 25.0 0.0 1.7 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 ETO25934.1 - 0.00022 20.6 0.0 0.00036 20.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Ribosomal_S7 PF00177.16 ETO25934.1 - 0.0028 17.2 0.0 0.0049 16.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e AAA_5 PF07728.9 ETO25934.1 - 0.0038 16.9 0.1 0.0077 15.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 ETO25934.1 - 0.01 16.1 0.0 0.01 16.1 0.0 2.5 3 1 0 3 3 2 0 AAA domain Arch_ATPase PF01637.13 ETO25934.1 - 0.011 15.4 0.0 3.8 7.1 0.0 2.3 1 1 1 2 2 2 0 Archaeal ATPase NACHT PF05729.7 ETO25934.1 - 0.019 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.1 ETO25934.1 - 0.04 13.3 0.1 0.1 11.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 ETO25934.1 - 0.04 12.8 0.1 0.16 10.8 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 ETO25934.1 - 0.046 13.4 0.0 0.091 12.5 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activat PF00158.21 ETO25934.1 - 0.085 12.3 0.0 0.14 11.6 0.0 1.5 1 1 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 ETO25934.1 - 0.09 11.9 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 ETO25934.1 - 0.12 11.4 0.3 0.4 9.6 0.2 1.8 1 1 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 ETO25934.1 - 0.15 12.2 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Homoserine_dh PF00742.14 ETO25935.1 - 2.4e-18 66.4 0.0 5.8e-18 65.1 0.0 1.6 1 1 0 1 1 1 1 Homoserine dehydrogenase TLD PF07534.11 ETO25936.1 - 4e-17 62.5 1.2 6.8e-17 61.7 0.9 1.4 1 0 0 1 1 1 1 TLD MIP-T3 PF10243.4 ETO25936.1 - 0.00027 19.5 53.5 0.0004 19.0 37.1 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Daxx PF03344.10 ETO25936.1 - 0.031 12.7 47.6 0.044 12.2 33.0 1.1 1 0 0 1 1 1 0 Daxx Family Daxx PF03344.10 ETO25937.1 - 0.0019 16.7 18.9 0.0022 16.6 13.1 1.0 1 0 0 1 1 1 1 Daxx Family DUF605 PF04652.11 ETO25937.1 - 0.058 12.7 26.9 0.071 12.5 18.7 1.0 1 0 0 1 1 1 0 Vta1 like DUF2457 PF10446.4 ETO25937.1 - 0.089 11.5 12.5 0.11 11.1 8.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TFIIF_alpha PF05793.7 ETO25937.1 - 0.14 10.5 25.0 0.16 10.3 17.3 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Lin-8 PF03353.10 ETO25937.1 - 0.25 10.5 15.1 0.31 10.3 10.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF1387 PF07139.6 ETO25937.1 - 1.3 8.5 15.2 1.4 8.4 10.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) MIP-T3 PF10243.4 ETO25937.1 - 3.6 5.9 25.4 4.1 5.7 17.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Nop14 PF04147.7 ETO25937.1 - 4.1 5.1 22.0 4.9 4.9 15.2 1.1 1 0 0 1 1 1 0 Nop14-like family APG6 PF04111.7 ETO25937.1 - 4.5 6.2 16.0 7 5.5 11.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 CDC45 PF02724.9 ETO25937.1 - 4.6 5.1 16.4 5.3 4.9 11.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF262 PF03235.9 ETO25937.1 - 4.8 7.0 10.0 7.3 6.4 6.9 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF262 GDI PF00996.13 ETO25938.1 - 5.6e-19 67.7 4.1 8.7e-17 60.5 0.2 2.3 1 1 1 2 2 2 2 GDP dissociation inhibitor DUF4087 PF13316.1 ETO25938.1 - 0.039 14.1 1.1 0.056 13.6 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4087) Prothymosin PF03247.9 ETO25938.1 - 0.12 12.5 27.0 0.08 13.1 14.6 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family Ctr PF04145.10 ETO25938.1 - 0.17 11.9 0.3 6.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Ctr copper transporter family GET2 PF08690.5 ETO25938.1 - 0.18 11.0 6.8 0.13 11.4 0.3 2.1 2 0 0 2 2 2 0 GET complex subunit GET2 Spore_coat_CotO PF14153.1 ETO25938.1 - 0.72 9.2 12.4 0.061 12.7 2.0 2.1 2 0 0 2 2 2 0 Spore coat protein CotO Trypan_PARP PF05887.6 ETO25938.1 - 1.9 8.2 6.0 3.2 7.5 4.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Spore_YhcN_YlaJ PF09580.5 ETO25938.1 - 2.8 8.0 14.1 0.74 9.8 5.2 2.1 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) FAM176 PF14851.1 ETO25938.1 - 7.6 6.1 10.2 0.65 9.6 2.3 2.1 2 0 0 2 2 2 0 FAM176 family Metallophos PF00149.23 ETO25938.1 - 9.5 5.5 6.9 17 4.7 4.3 1.6 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase Ribosomal_L28e PF01778.12 ETO25939.1 - 0.012 15.9 2.5 0.033 14.5 1.8 1.7 1 0 0 1 1 1 0 Ribosomal L28e protein family PDZ PF00595.19 ETO25941.1 - 0.017 15.2 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) Lipoprotein_20 PF13942.1 ETO25942.1 - 0.023 14.2 0.4 0.064 12.7 0.1 1.8 2 0 0 2 2 2 0 YfhG lipoprotein Sex_peptide PF08138.6 ETO25942.1 - 0.061 13.1 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Sex peptide (SP) family ArfGap PF01412.13 ETO25943.1 - 9e-34 115.7 0.1 9e-34 115.7 0.1 2.8 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf PH PF00169.24 ETO25943.1 - 2e-08 34.3 4.3 5.1e-08 33.0 0.1 3.0 3 0 0 3 3 3 1 PH domain Ank_2 PF12796.2 ETO25943.1 - 5.4e-07 29.8 0.3 1.8e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) PH_11 PF15413.1 ETO25943.1 - 1.3e-06 28.6 2.7 1.6e-06 28.3 0.1 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain Ank PF00023.25 ETO25943.1 - 6.1e-06 25.7 0.3 3.4e-05 23.4 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 ETO25943.1 - 0.00011 22.3 0.0 0.00011 22.3 0.0 2.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) PH_8 PF15409.1 ETO25943.1 - 0.0011 18.9 0.1 0.0031 17.5 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Ank_3 PF13606.1 ETO25943.1 - 0.0048 17.0 0.0 0.041 14.1 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 ETO25943.1 - 0.088 13.3 0.0 0.91 10.1 0.0 2.5 1 1 1 2 2 2 0 Ankyrin repeats (many copies) MUG113 PF13455.1 ETO25943.1 - 0.26 11.7 2.0 0.41 11.1 0.0 2.4 3 0 0 3 3 3 0 Meiotically up-regulated gene 113 Phage_Mu_Gp45 PF06890.7 ETO25944.1 - 0.003 17.0 3.1 0.0064 15.9 1.9 1.8 1 1 0 1 1 1 1 Bacteriophage Mu Gp45 protein DUF3306 PF11748.3 ETO25945.1 - 0.035 14.7 1.8 0.046 14.3 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Med10 PF09748.4 ETO25946.1 - 1.9e-11 43.8 1.6 5.8e-11 42.3 1.1 1.8 1 1 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex PIG-S PF10510.4 ETO25946.1 - 0.019 13.6 0.0 0.021 13.5 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein PP2C_C PF07830.8 ETO25946.1 - 0.13 12.4 1.3 0.53 10.4 0.7 2.0 1 1 1 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain DUF16 PF01519.11 ETO25946.1 - 0.4 10.9 4.0 0.74 10.0 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF4061 PF13270.1 ETO25946.1 - 4.9 7.3 6.3 15 5.7 0.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4061) Pro-kuma_activ PF09286.6 ETO25947.1 - 4.5e-22 78.6 0.6 1.1e-21 77.4 0.4 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain RICTOR_phospho PF14665.1 ETO25947.1 - 0.29 11.2 2.7 0.36 10.9 0.0 2.3 2 1 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site Prok-E2_E PF14462.1 ETO25948.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family E TPR_11 PF13414.1 ETO25949.1 - 1.6e-25 88.5 13.3 5.5e-10 38.7 0.1 5.3 2 2 2 5 5 5 5 TPR repeat TPR_1 PF00515.23 ETO25949.1 - 2.7e-21 74.2 15.0 0.00026 20.4 0.0 6.7 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO25949.1 - 2.1e-19 67.8 15.2 0.00037 20.1 0.0 7.1 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 ETO25949.1 - 1.3e-15 56.2 10.4 0.00089 19.2 0.1 6.1 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO25949.1 - 2.1e-14 52.7 2.6 0.01 16.3 0.2 6.1 4 3 3 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO25949.1 - 3.6e-13 49.7 4.1 0.0012 19.4 0.0 4.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO25949.1 - 1.6e-09 36.8 7.5 0.0039 16.8 0.4 5.7 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO25949.1 - 1.8e-09 37.3 8.8 0.004 17.0 0.3 4.8 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 ETO25949.1 - 2.3e-09 37.4 2.6 0.005 17.1 0.0 4.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO25949.1 - 3.3e-05 23.3 2.9 0.4 10.5 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO25949.1 - 0.0017 18.6 2.1 12 6.6 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.7 ETO25949.1 - 0.0031 17.2 0.1 2.5 8.0 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.1 ETO25949.1 - 0.01 15.9 0.8 7 6.8 0.0 3.7 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 ETO25949.1 - 0.016 15.0 0.4 6.5 6.8 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.1 ETO25949.1 - 0.017 14.2 1.4 0.23 10.5 0.0 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat Coatomer_E PF04733.9 ETO25949.1 - 0.042 13.0 0.0 0.14 11.3 0.0 1.9 1 1 1 2 2 2 0 Coatomer epsilon subunit TPR_9 PF13371.1 ETO25949.1 - 0.042 13.7 2.5 0.58 10.0 0.0 3.2 2 2 1 3 3 3 0 Tetratricopeptide repeat PAXIP1_C PF15364.1 ETO25949.1 - 0.16 11.9 2.1 0.3 11.0 1.4 1.4 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Acetyltransf_CG PF14542.1 ETO25950.1 - 4.1e-13 49.0 0.1 5.7e-13 48.5 0.1 1.2 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.1 ETO25950.1 - 2e-06 27.8 0.1 9.5e-06 25.6 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETO25950.1 - 0.0003 20.7 0.0 0.0016 18.4 0.0 1.9 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 ETO25950.1 - 0.0017 18.5 0.0 0.002 18.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETO25950.1 - 0.0021 17.7 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 ETO25950.1 - 0.0037 17.1 0.0 0.0074 16.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Baculo_E66 PF04850.7 ETO25950.1 - 0.0048 15.9 0.2 0.0052 15.8 0.1 1.0 1 0 0 1 1 1 1 Baculovirus E66 occlusion-derived virus envelope protein Acetyltransf_10 PF13673.1 ETO25950.1 - 0.031 14.3 0.0 0.042 13.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NIF PF03031.13 ETO25954.1 - 0.087 12.4 0.0 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase ABC2_membrane_3 PF12698.2 ETO25955.1 - 7.9e-12 44.8 33.3 4.7e-11 42.3 22.5 2.3 1 1 0 1 1 1 1 ABC-2 family transporter protein Myosin_head PF00063.16 ETO25957.1 - 1.5e-102 343.9 5.4 1.8e-102 343.6 3.8 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) BLVR PF06375.6 ETO25958.1 - 2.1 8.1 10.8 3.2 7.5 7.5 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) FLO_LFY PF01698.11 ETO25958.1 - 2.1 7.0 6.3 2.7 6.7 4.4 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein NARP1 PF12569.3 ETO25958.1 - 5.6 5.5 7.9 7.9 5.0 5.5 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4156 PF13698.1 ETO25959.1 - 0.077 12.8 0.7 0.21 11.5 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4156) DUF2175 PF09943.4 ETO25959.1 - 0.67 10.0 6.9 2.6 8.1 4.8 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) DUF2140 PF09911.4 ETO25959.1 - 8.3 5.5 8.0 11 5.1 4.8 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) HgmA PF04209.8 ETO25960.1 - 1.4e-59 201.6 0.0 2.2e-35 121.8 0.0 2.0 1 1 1 2 2 2 2 homogentisate 1,2-dioxygenase PUF PF00806.14 ETO25963.1 - 1.9e-18 64.8 2.0 6.7e-05 22.1 0.0 5.6 5 0 0 5 5 5 3 Pumilio-family RNA binding repeat DUF1687 PF07955.6 ETO25963.1 - 0.014 15.3 0.0 0.057 13.4 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1687) HNOB PF07700.10 ETO25963.1 - 0.022 14.2 3.0 17 4.8 0.1 4.0 3 1 1 4 4 4 0 Heme NO binding PepX_C PF08530.5 ETO25964.1 - 6.9e-34 117.6 0.0 1.1e-33 116.9 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.13 ETO25964.1 - 1.7e-11 44.0 7.7 2.8e-08 33.5 1.2 2.2 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Mob1_phocein PF03637.12 ETO25965.1 - 3.7e-24 85.3 0.5 6e-14 52.0 0.0 2.2 2 0 0 2 2 2 2 Mob1/phocein family BUD22 PF09073.5 ETO25966.1 - 0.00034 19.8 4.3 0.00038 19.6 3.0 1.0 1 0 0 1 1 1 1 BUD22 PSD2 PF07624.6 ETO25966.1 - 0.11 12.1 0.2 0.27 10.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1585) Shisa PF13908.1 ETO25967.1 - 0.043 14.0 0.5 0.043 14.0 0.3 1.7 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Herpes_gE PF02480.11 ETO25967.1 - 0.061 11.5 0.0 0.1 10.8 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Adeno_E3_CR2 PF02439.10 ETO25967.1 - 3.6 7.1 10.1 0.46 10.0 3.6 1.8 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 TPR_11 PF13414.1 ETO25968.1 - 4.1e-07 29.5 9.5 0.094 12.3 0.1 3.8 2 1 2 4 4 4 4 TPR repeat TPR_14 PF13428.1 ETO25968.1 - 2.3e-06 27.7 0.1 0.21 12.2 0.0 4.2 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO25968.1 - 4e-05 23.4 10.2 1.2 9.1 0.0 4.8 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO25968.1 - 5.7e-05 23.3 1.0 0.12 12.7 0.2 3.4 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO25968.1 - 0.00067 20.2 2.7 0.81 10.4 0.1 4.0 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO25968.1 - 0.002 17.7 15.6 0.018 14.8 0.0 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO25968.1 - 0.0075 15.9 2.0 3.3 7.7 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO25968.1 - 0.083 12.5 8.9 0.26 10.9 0.3 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETO25968.1 - 0.089 12.7 13.8 2.1 8.4 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 ETO25968.1 - 0.28 11.0 1.8 0.88 9.4 0.0 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat Metallophos PF00149.23 ETO25970.1 - 0.025 13.9 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase WD40 PF00400.27 ETO25971.1 - 6.9e-46 152.5 18.6 2.5e-10 39.8 0.2 6.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO25971.1 - 2.8e-11 42.2 2.6 0.00066 17.9 0.0 5.1 3 2 1 5 5 5 5 Nucleoporin Nup120/160 HSP20 PF00011.16 ETO25972.1 - 0.11 12.4 0.0 0.53 10.1 0.0 2.0 2 0 0 2 2 2 0 Hsp20/alpha crystallin family WD40 PF00400.27 ETO25973.1 - 1.1e-73 240.7 17.5 7.7e-12 44.6 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO25973.1 - 1.3e-08 34.7 0.1 1.5e-05 24.7 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO25973.1 - 3.4e-08 32.1 2.1 0.0013 17.0 0.1 3.7 1 1 3 4 4 4 2 Cytochrome D1 heme domain Nup160 PF11715.3 ETO25973.1 - 2.8e-07 29.0 4.4 0.046 11.8 0.2 4.8 1 1 2 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO25973.1 - 2.2e-06 27.3 0.2 0.00032 20.2 0.0 3.0 1 1 0 2 2 2 1 PQQ-like domain Kelch_6 PF13964.1 ETO25973.1 - 0.00019 21.4 9.7 0.012 15.7 0.7 4.9 4 1 1 5 5 5 1 Kelch motif Kelch_4 PF13418.1 ETO25973.1 - 0.0012 18.5 0.3 0.82 9.4 0.1 3.7 3 0 0 3 3 3 1 Galactose oxidase, central domain BBS2_Mid PF14783.1 ETO25973.1 - 0.0013 18.4 0.8 16 5.3 0.0 4.6 3 3 2 5 5 5 0 Ciliary BBSome complex subunit 2, middle region PD40 PF07676.7 ETO25973.1 - 0.0062 16.1 10.5 7 6.4 0.0 5.7 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat DUF1513 PF07433.6 ETO25973.1 - 0.014 14.2 0.1 3.2 6.5 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) Kelch_3 PF13415.1 ETO25973.1 - 0.083 13.0 0.1 0.3 11.3 0.0 2.0 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO25973.1 - 0.29 10.6 3.0 0.29 10.6 0.5 2.1 2 0 0 2 2 2 0 Kelch motif Proteasome_A_N PF10584.4 ETO25973.1 - 0.31 10.4 3.9 31 4.0 0.0 4.3 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature CH PF00307.26 ETO25974.1 - 0.016 15.2 0.1 0.096 12.7 0.0 2.2 2 1 0 2 2 2 0 Calponin homology (CH) domain Peptidase_C54 PF03416.14 ETO25974.1 - 0.097 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C54 WD40 PF00400.27 ETO25975.1 - 1.7e-08 34.0 1.2 0.0016 18.2 0.2 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat CH PF00307.26 ETO25976.1 - 1.7e-18 66.6 0.0 1.5e-11 44.2 0.0 2.4 2 1 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 ETO25976.1 - 3.4e-05 23.4 0.0 7.4e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 CAMSAP CH domain zf-C3HC4_2 PF13923.1 ETO25977.1 - 4.5e-05 23.3 4.4 4.5e-05 23.3 3.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO25977.1 - 6.4e-05 22.5 2.5 6.4e-05 22.5 1.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO25977.1 - 0.00021 20.8 5.6 0.00021 20.8 3.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO25977.1 - 0.0013 18.4 4.9 0.0023 17.7 2.0 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 ETO25977.1 - 0.0051 16.5 4.8 0.0051 16.5 3.3 2.1 2 0 0 2 2 2 1 zinc-RING finger domain Ins_P5_2-kin PF06090.7 ETO25977.1 - 0.012 14.7 2.2 0.017 14.2 1.2 1.3 1 1 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase UBA PF00627.26 ETO25977.1 - 0.017 14.9 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain zf-RING_UBOX PF13445.1 ETO25977.1 - 0.029 14.0 1.9 0.074 12.7 1.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger XOO_2897-deam PF14440.1 ETO25977.1 - 0.39 10.4 2.5 13 5.5 0.8 2.4 2 0 0 2 2 2 0 Xanthomonas XOO_2897-like deaminase PI3Ka PF00613.15 ETO25978.1 - 2e-50 170.5 1.4 8.2e-50 168.5 1.3 1.7 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 ETO25978.1 - 1.1e-10 41.4 0.0 6.8e-10 38.8 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Utp13 PF08625.6 ETO25979.1 - 2.7e-35 121.0 1.2 7.5e-35 119.6 0.9 1.8 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.27 ETO25979.1 - 3.5e-34 115.4 18.9 5.3e-08 32.4 0.9 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat His_Phos_2 PF00328.17 ETO25980.1 - 1.8e-05 24.2 0.1 2.2e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) CAP_GLY PF01302.20 ETO25981.1 - 1.2e-12 47.3 0.5 1.9e-12 46.6 0.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain CH PF00307.26 ETO25983.1 - 1e-05 25.5 1.0 0.0027 17.7 0.0 3.5 3 1 0 3 3 3 2 Calponin homology (CH) domain CH PF00307.26 ETO25984.1 - 4.2e-27 94.3 0.7 3.2e-16 59.3 0.1 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 ETO25984.1 - 3.6e-07 29.7 0.1 9.8e-07 28.3 0.0 1.8 1 0 0 1 1 1 1 CAMSAP CH domain DUF1042 PF06294.6 ETO25984.1 - 0.023 14.3 0.2 0.054 13.0 0.0 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1042) Secretin_N_2 PF07655.8 ETO25986.1 - 0.14 12.5 6.9 0.98 9.8 0.0 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain GTP_EFTU PF00009.22 ETO25987.1 - 4.8e-10 39.1 0.3 5.5e-07 29.1 0.1 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 ETO25988.1 - 1.7e-07 31.1 0.1 4.1e-05 23.5 0.1 2.4 2 0 0 2 2 2 2 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 ETO25988.1 - 5.4e-07 29.6 0.4 1.3e-06 28.4 0.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RRM_1 PF00076.17 ETO25989.1 - 5.9e-07 29.0 0.0 9.7e-07 28.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO25989.1 - 0.00064 19.6 0.0 0.00094 19.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO25989.1 - 0.0051 16.6 0.0 0.0094 15.7 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PBP_sp32 PF07222.7 ETO25989.1 - 0.089 11.9 3.2 0.085 12.0 2.2 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF3596 PF12167.3 ETO25989.1 - 0.24 10.9 1.4 0.55 9.7 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3596) CorA PF01544.13 ETO25990.1 - 2.5e-10 39.8 0.2 3.9e-10 39.2 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Leuk-A4-hydro_C PF09127.6 ETO25990.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal DUF4203 PF13886.1 ETO25990.1 - 0.067 12.6 0.4 0.1 12.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) GWT1 PF06423.7 ETO25990.1 - 0.09 12.8 0.2 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 GWT1 PrmA PF06325.8 ETO25992.1 - 0.058 12.5 0.1 0.068 12.2 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) V_ATPase_I PF01496.14 ETO25992.1 - 0.18 9.6 2.6 0.22 9.3 1.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Syntaxin_2 PF14523.1 ETO25992.1 - 1.1 9.2 4.4 14 5.7 3.1 2.2 1 1 0 1 1 1 0 Syntaxin-like protein 4HB_MCP_1 PF12729.2 ETO25992.1 - 1.4 8.2 4.9 0.74 9.1 1.9 1.5 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction NPV_P10 PF05531.7 ETO25992.1 - 1.5 9.1 7.7 1.4 9.2 1.8 2.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Phage_GP20 PF06810.6 ETO25992.1 - 2.6 7.4 11.1 0.2 11.0 3.4 2.1 2 1 1 3 3 3 0 Phage minor structural protein GP20 SAM_PNT PF02198.11 ETO25993.1 - 0.031 14.0 0.1 0.068 12.9 0.1 1.6 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Med10 PF09748.4 ETO25993.1 - 0.11 12.3 1.7 0.5 10.1 1.1 2.0 1 1 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex DUF972 PF06156.8 ETO25993.1 - 0.11 12.8 13.0 0.19 12.0 1.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) SYF2 PF08231.7 ETO25993.1 - 0.17 11.9 6.6 0.48 10.5 4.6 1.8 1 1 0 1 1 1 0 SYF2 splicing factor Prefoldin PF02996.12 ETO25993.1 - 1.1 8.9 10.9 0.11 12.1 0.7 2.7 2 1 1 3 3 3 0 Prefoldin subunit COG2 PF06148.6 ETO25993.1 - 1.2 9.0 9.0 0.13 12.1 1.3 2.2 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 LuxE PF04443.7 ETO25995.1 - 0.038 12.6 0.1 0.048 12.3 0.1 1.2 1 0 0 1 1 1 0 Acyl-protein synthetase, LuxE NAD_binding_6 PF08030.7 ETO25996.1 - 1.8 8.4 10.1 7.3 6.4 0.4 2.2 2 0 0 2 2 2 0 Ferric reductase NAD binding domain DUF936 PF06075.7 ETO25996.1 - 3 6.6 24.3 3.7 6.3 16.8 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Amnionless PF14828.1 ETO25997.1 - 7.4e-05 21.4 0.4 9.2e-05 21.1 0.3 1.1 1 0 0 1 1 1 1 Amnionless Mtp PF03821.11 ETO25997.1 - 0.0047 16.3 0.1 0.006 15.9 0.1 1.2 1 0 0 1 1 1 1 Golgi 4-transmembrane spanning transporter FtsL PF04999.8 ETO25997.1 - 0.005 16.5 0.1 0.0088 15.7 0.1 1.4 1 0 0 1 1 1 1 Cell division protein FtsL Calcyon PF06387.6 ETO25997.1 - 0.0054 16.1 0.1 0.0081 15.5 0.0 1.2 1 0 0 1 1 1 1 D1 dopamine receptor-interacting protein (calcyon) DUF1049 PF06305.6 ETO25997.1 - 0.0069 15.8 0.2 0.016 14.6 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1049) TMEM154 PF15102.1 ETO25997.1 - 0.0074 15.9 0.4 0.011 15.4 0.3 1.3 1 0 0 1 1 1 1 TMEM154 protein family OATP PF03137.15 ETO25997.1 - 0.008 14.2 0.3 0.0095 14.0 0.2 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family 7TM_GPCR_Srd PF10317.4 ETO25997.1 - 0.0096 14.9 0.6 0.013 14.4 0.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd GP41 PF00517.12 ETO25997.1 - 0.017 14.7 1.0 0.032 13.8 0.7 1.5 1 0 0 1 1 1 0 Retroviral envelope protein Scs3p PF10261.4 ETO25997.1 - 0.023 13.7 0.1 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Herpes_gE PF02480.11 ETO25997.1 - 0.037 12.3 0.0 0.046 11.9 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Herpes_UL45 PF05473.7 ETO25997.1 - 0.039 13.3 0.1 0.065 12.6 0.1 1.3 1 0 0 1 1 1 0 UL45 protein Kei1 PF08552.6 ETO25997.1 - 0.04 13.5 0.9 1.4 8.5 0.0 2.1 1 1 1 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Shisa PF13908.1 ETO25997.1 - 0.049 13.7 1.9 0.08 13.1 1.3 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Tmemb_9 PF05434.6 ETO25997.1 - 0.054 13.2 0.6 0.091 12.5 0.4 1.5 1 0 0 1 1 1 0 TMEM9 DUF4234 PF14018.1 ETO25997.1 - 0.091 12.5 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) TraL PF07178.6 ETO25997.1 - 0.096 12.7 0.8 14 5.7 0.3 2.3 2 0 0 2 2 2 0 TraL protein SR-25 PF10500.4 ETO25997.1 - 0.12 11.8 6.5 0.27 10.6 4.5 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF912 PF06024.7 ETO25997.1 - 0.14 12.1 4.4 0.11 12.6 1.1 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1510 PF07423.6 ETO25998.1 - 0.00057 19.3 11.2 0.00081 18.8 7.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Ycf1 PF05758.7 ETO25998.1 - 0.032 11.9 5.7 0.034 11.8 4.0 1.0 1 0 0 1 1 1 0 Ycf1 DUF262 PF03235.9 ETO25998.1 - 0.046 13.6 3.5 0.057 13.3 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 Zip PF02535.17 ETO25998.1 - 0.067 12.1 0.9 0.081 11.9 0.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RNase_H2-Ydr279 PF09468.5 ETO25998.1 - 0.15 11.2 11.2 0.19 10.8 7.8 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) RR_TM4-6 PF06459.7 ETO25998.1 - 0.22 11.3 9.3 0.29 10.9 6.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 U79_P34 PF03064.11 ETO25998.1 - 0.27 10.7 11.1 0.35 10.3 7.7 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF4094 PF13334.1 ETO25998.1 - 0.36 11.2 0.0 0.36 11.2 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) CT47 PF15623.1 ETO25998.1 - 0.43 10.2 10.2 0.52 10.0 7.1 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 DDHD PF02862.12 ETO25998.1 - 0.46 10.2 5.5 0.61 9.8 3.8 1.2 1 0 0 1 1 1 0 DDHD domain CDC27 PF09507.5 ETO25998.1 - 1.3 8.1 24.8 0.71 9.0 15.5 1.7 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Herpes_DNAp_acc PF04929.7 ETO25998.1 - 1.6 7.5 8.3 1.8 7.4 5.7 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Rtf2 PF04641.7 ETO25998.1 - 2.3 7.3 15.1 3.4 6.7 10.5 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger YMF19 PF02326.10 ETO25998.1 - 3.6 8.2 6.1 0.99 10.0 0.2 2.1 1 1 1 2 2 2 0 Plant ATP synthase F0 MIP-T3 PF10243.4 ETO25998.1 - 5.3 5.3 23.5 6.4 5.1 16.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF3881 PF12997.2 ETO25998.1 - 6.8 5.6 6.7 0.32 9.9 0.8 1.5 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3881) Thioredoxin PF00085.15 ETO26000.1 - 7.2e-24 83.4 0.2 9.2e-24 83.1 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 ETO26000.1 - 0.0008 19.4 0.1 0.0024 17.9 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_6 PF13848.1 ETO26000.1 - 0.01 15.6 0.1 0.013 15.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_2 PF13098.1 ETO26000.1 - 0.014 15.6 0.1 0.048 13.8 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_7 PF13899.1 ETO26000.1 - 0.017 15.1 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.1 ETO26000.1 - 0.039 13.5 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Mucin PF01456.12 ETO26001.1 - 1.8 8.3 48.1 3.4 7.4 33.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Rifin_STEVOR PF02009.11 ETO26001.1 - 4.2 6.9 10.3 9.8 5.7 0.0 2.4 1 1 0 2 2 2 0 Rifin/stevor family DnaJ PF00226.26 ETO26003.1 - 0.0022 17.6 0.0 0.0036 16.9 0.0 1.5 1 1 0 1 1 1 1 DnaJ domain Bcl-2_3 PF15286.1 ETO26003.1 - 0.037 14.4 0.0 0.044 14.2 0.0 1.2 1 0 0 1 1 1 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like N_Asn_amidohyd PF14736.1 ETO26004.1 - 5.2e-13 48.4 0.8 6.8e-13 48.1 0.6 1.0 1 0 0 1 1 1 1 Protein N-terminal asparagine amidohydrolase DUF1448 PF07289.6 ETO26004.1 - 0.046 12.6 0.1 0.051 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1448) Cag12 PF13117.1 ETO26004.1 - 0.069 13.0 0.2 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 Cag pathogenicity island protein Cag12 CCDC50_N PF15295.1 ETO26005.1 - 0.024 14.5 2.1 0.048 13.5 1.5 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus Peptidase_S49_N PF08496.5 ETO26006.1 - 0.03 14.0 2.7 0.048 13.4 1.9 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal UPF0102 PF02021.12 ETO26006.1 - 0.13 12.2 0.7 0.22 11.4 0.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0102 TMEM191C PF15194.1 ETO26007.1 - 0.071 12.9 0.0 0.18 11.7 0.0 1.6 1 1 0 1 1 1 0 TMEM191C family Vicilin_N PF04702.7 ETO26007.1 - 2.9 7.5 15.7 0.33 10.5 2.7 2.5 3 0 0 3 3 3 0 Vicilin N terminal region GWT1 PF06423.7 ETO26009.1 - 1.7 8.7 6.5 6.4 6.8 4.3 2.2 1 1 0 1 1 1 0 GWT1 Prenylcys_lyase PF07156.9 ETO26010.1 - 1.1e-16 60.6 1.3 2.7e-16 59.4 0.9 1.5 1 1 0 1 1 1 1 Prenylcysteine lyase Pkinase PF00069.20 ETO26011.1 - 8.1e-22 77.6 0.5 6e-21 74.7 0.3 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO26011.1 - 0.0074 15.3 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO26011.1 - 0.014 14.4 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 ETO26011.1 - 0.046 13.0 0.0 0.087 12.1 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 ETO26011.1 - 0.097 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family BING4CT PF08149.6 ETO26012.1 - 1.8e-33 113.8 0.2 1.7e-32 110.7 0.0 2.6 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.27 ETO26012.1 - 0.18 11.7 1.0 4.3 7.3 0.0 3.4 4 0 0 4 4 4 0 WD domain, G-beta repeat WD40 PF00400.27 ETO26014.1 - 7e-63 206.4 19.7 4.2e-10 39.1 0.1 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO26014.1 - 2.3e-11 42.5 3.9 0.00022 19.5 0.0 5.2 1 1 4 5 5 5 4 Nucleoporin Nup120/160 HAD PF12710.2 ETO26014.1 - 0.26 11.4 1.6 9.5 6.3 1.1 3.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Osteopontin PF00865.13 ETO26015.1 - 0.26 10.4 15.8 0.55 9.4 10.9 1.4 1 0 0 1 1 1 0 Osteopontin PRANC PF09372.5 ETO26016.1 - 8.6 6.4 9.8 0.54 10.2 2.1 2.6 2 1 1 3 3 3 0 PRANC domain TruB_N PF01509.13 ETO26018.1 - 7.4e-19 68.3 9.1 9.2e-13 48.6 0.0 4.6 3 1 1 4 4 4 2 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 ETO26018.1 - 2.2e-17 62.5 1.3 4.9e-17 61.4 0.9 1.6 1 0 0 1 1 1 1 PUA domain DKCLD PF08068.7 ETO26018.1 - 2.1e-08 33.9 2.2 2e-07 30.8 0.1 3.4 4 0 0 4 4 4 1 DKCLD (NUC011) domain Glyco_hydro_9 PF00759.14 ETO26018.1 - 0.022 13.6 0.0 2.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 9 Beta_helix PF13229.1 ETO26019.1 - 0.00018 21.2 7.1 0.00063 19.5 5.0 1.8 1 1 0 1 1 1 1 Right handed beta helix region PBP1_TM PF14812.1 ETO26020.1 - 0.072 13.3 6.5 0.16 12.3 1.1 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal cwf18 PF08315.7 ETO26021.1 - 1.7e-16 60.8 9.2 1.7e-16 60.8 6.4 2.1 1 1 1 2 2 2 1 cwf18 pre-mRNA splicing factor Pox_A31 PF05771.6 ETO26021.1 - 0.036 13.8 0.2 0.055 13.2 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A31 protein RLL PF10036.4 ETO26021.1 - 1.6 8.0 14.5 1 8.7 7.6 2.0 1 1 1 2 2 2 0 Putative carnitine deficiency-associated protein SMN PF06003.7 ETO26021.1 - 9.2 5.2 11.7 4.3 6.3 1.6 2.1 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) MIP-T3 PF10243.4 ETO26022.1 - 0.0025 16.3 37.4 0.0029 16.1 25.9 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 NARP1 PF12569.3 ETO26022.1 - 0.02 13.6 23.1 0.024 13.3 16.0 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SprA-related PF12118.3 ETO26022.1 - 0.025 13.9 20.2 0.026 13.8 14.0 1.1 1 0 0 1 1 1 0 SprA-related family DUF3337 PF11816.3 ETO26022.1 - 0.16 11.3 20.9 0.18 11.2 14.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) CAF-1_p150 PF11600.3 ETO26022.1 - 0.17 11.2 54.3 0.21 10.9 37.6 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CDC27 PF09507.5 ETO26022.1 - 0.23 10.6 33.3 0.24 10.5 23.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RICTOR_N PF14664.1 ETO26022.1 - 0.42 9.1 8.2 0.11 11.0 3.8 1.4 1 1 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term LMBR1 PF04791.11 ETO26022.1 - 0.68 8.4 12.2 0.72 8.3 8.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein NAM-associated PF14303.1 ETO26022.1 - 0.7 10.1 35.3 0.83 9.9 24.5 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain SAGA-Tad1 PF12767.2 ETO26022.1 - 0.78 9.3 16.4 1 8.9 11.4 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Raftlin PF15250.1 ETO26022.1 - 0.91 7.9 13.3 1.2 7.5 9.2 1.4 1 0 0 1 1 1 0 Raftlin BTV_NS2 PF04514.7 ETO26022.1 - 1.1 8.0 21.4 1.2 7.8 14.9 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF4407 PF14362.1 ETO26022.1 - 1.2 8.0 11.4 1.6 7.6 7.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.7 ETO26022.1 - 1.5 8.6 26.6 2 8.2 18.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Herpes_UL95 PF03038.9 ETO26022.1 - 1.9 7.3 7.6 2.4 6.9 5.2 1.1 1 0 0 1 1 1 0 UL95 family GAGA_bind PF06217.7 ETO26022.1 - 2.3 8.1 29.5 3.1 7.6 20.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Neur_chan_memb PF02932.11 ETO26022.1 - 3.4 7.4 10.9 4.5 7.0 7.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF262 PF03235.9 ETO26022.1 - 3.5 7.5 15.1 4.5 7.1 10.5 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF262 Ndc1_Nup PF09531.5 ETO26022.1 - 3.6 5.9 13.0 3.8 5.8 9.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOBP PF15279.1 ETO26022.1 - 3.7 7.8 13.6 4 7.7 9.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Asp-B-Hydro_N PF05279.6 ETO26022.1 - 4.4 7.0 23.7 5 6.8 16.4 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Atg14 PF10186.4 ETO26022.1 - 4.8 6.0 27.9 6.4 5.6 19.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ycf1 PF05758.7 ETO26022.1 - 5.2 4.6 23.3 5.8 4.4 16.2 1.1 1 0 0 1 1 1 0 Ycf1 DUF936 PF06075.7 ETO26022.1 - 6.2 5.6 22.5 7.1 5.4 15.6 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) PLRV_ORF5 PF01690.12 ETO26022.1 - 6.9 5.6 17.1 7.6 5.5 11.9 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein PXA PF02194.10 ETO26022.1 - 7 6.1 12.5 12 5.3 8.6 1.5 1 1 0 1 1 1 0 PXA domain Parvo_coat PF00740.13 ETO26022.1 - 7.4 5.4 7.8 8.1 5.2 5.4 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Peptidase_A21 PF03566.8 ETO26022.1 - 8.6 4.3 8.0 12 3.8 5.5 1.2 1 0 0 1 1 1 0 Peptidase family A21 Na_trans_assoc PF06512.8 ETO26023.1 - 2.2 8.1 18.6 3.3 7.6 12.9 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Macro PF01661.16 ETO26024.1 - 5.2e-27 94.0 0.1 1.2e-26 92.9 0.0 1.7 1 0 0 1 1 1 1 Macro domain DUF3991 PF13154.1 ETO26024.1 - 0.8 9.9 4.2 1.1 9.5 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3991) WD40 PF00400.27 ETO26025.1 - 2.1e-13 49.5 3.4 3.4e-07 29.8 0.1 3.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Ion_trans PF00520.26 ETO26027.1 - 2.6e-27 95.3 24.5 2.4e-25 88.9 8.2 3.2 3 1 0 3 3 3 2 Ion transport protein NicO PF03824.11 ETO26028.1 - 0.034 13.4 0.3 0.044 13.1 0.2 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein Rifin_STEVOR PF02009.11 ETO26028.1 - 0.035 13.7 2.9 0.043 13.4 2.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family YukC PF10140.4 ETO26028.1 - 0.062 11.8 1.9 0.064 11.8 1.3 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC DUF912 PF06024.7 ETO26028.1 - 0.066 13.2 1.6 0.094 12.7 1.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Herpes_LMP1 PF05297.6 ETO26028.1 - 0.068 12.0 1.0 0.072 12.0 0.7 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Nairovirus_M PF07948.6 ETO26028.1 - 0.16 10.0 4.8 0.18 9.8 3.3 1.1 1 0 0 1 1 1 0 Nairovirus M polyprotein-like Ion_trans PF00520.26 ETO26029.1 - 2.4e-14 53.0 13.5 3.4e-14 52.5 9.4 1.2 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.7 ETO26029.1 - 7.7e-06 24.5 7.1 1.1e-05 24.1 4.9 1.2 1 0 0 1 1 1 1 Polycystin cation channel DUF3715 PF12509.3 ETO26029.1 - 0.078 12.8 0.6 0.14 12.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3715) SR-25 PF10500.4 ETO26030.1 - 2.1 7.7 6.0 3.4 7.0 4.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Hum_adeno_E3A PF05393.6 ETO26031.1 - 0.068 12.8 0.0 0.47 10.1 0.0 2.5 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein DUF4492 PF14899.1 ETO26031.1 - 0.68 9.4 0.0 1.3 8.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) DUF3938 PF13074.1 ETO26032.1 - 0.00074 19.3 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3938) DUF695 PF05117.7 ETO26032.1 - 0.033 14.1 0.3 0.071 13.0 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF695) Peptidase_C80 PF11713.3 ETO26032.1 - 0.045 13.5 0.2 0.086 12.6 0.2 1.5 1 0 0 1 1 1 0 Peptidase C80 family GerA PF03323.8 ETO26032.1 - 0.11 10.6 0.9 0.16 10.0 0.6 1.2 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein MFS_1 PF07690.11 ETO26033.1 - 5.2e-06 25.4 0.0 6.5e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MASE1 PF05231.9 ETO26033.1 - 0.0062 15.5 0.6 0.008 15.2 0.4 1.2 1 0 0 1 1 1 1 MASE1 SNARE_assoc PF09335.6 ETO26033.1 - 0.0066 16.6 0.5 0.015 15.5 0.2 1.7 1 1 0 1 1 1 1 SNARE associated Golgi protein AA_permease_2 PF13520.1 ETO26033.1 - 0.0075 14.8 0.2 0.011 14.2 0.1 1.2 1 1 0 1 1 1 1 Amino acid permease 2TM PF13239.1 ETO26033.1 - 0.024 14.7 1.7 0.24 11.4 0.3 2.1 2 0 0 2 2 2 0 2TM domain IFNGR1 PF07140.6 ETO26033.1 - 0.043 13.5 0.3 0.053 13.2 0.2 1.2 1 0 0 1 1 1 0 Interferon gamma receptor (IFNGR1) DUF2207 PF09972.4 ETO26033.1 - 0.05 12.1 0.9 0.059 11.9 0.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2244 PF10003.4 ETO26033.1 - 0.069 12.5 0.1 1.9 7.8 0.0 2.0 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Hjc PF01870.13 ETO26033.1 - 0.11 12.0 1.4 0.15 11.6 1.0 1.4 1 1 0 1 1 1 0 Archaeal holliday junction resolvase (hjc) DUF1212 PF06738.7 ETO26033.1 - 0.17 11.3 1.2 0.32 10.4 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) FAM176 PF14851.1 ETO26033.1 - 0.3 10.7 0.1 0.3 10.7 0.0 1.6 2 0 0 2 2 2 0 FAM176 family UPF0104 PF03706.8 ETO26033.1 - 0.5 9.5 5.0 0.15 11.2 0.4 1.9 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0104) Vpu PF00558.14 ETO26033.1 - 0.62 9.6 4.7 2.4 7.7 3.3 1.9 1 1 0 1 1 1 0 Vpu protein BPD_transp_2 PF02653.11 ETO26033.1 - 10 5.0 12.6 6 5.7 3.7 2.0 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component Destabilase PF05497.7 ETO26034.1 - 6e-08 32.8 0.2 1e-07 32.0 0.1 1.3 1 0 0 1 1 1 1 Destabilase GKAP PF03359.8 ETO26034.1 - 0.15 11.6 9.5 0.19 11.3 6.6 1.1 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein PAT1 PF09770.4 ETO26034.1 - 8.5 4.4 21.6 9.7 4.2 15.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4557 PF15101.1 ETO26034.1 - 9.8 5.9 10.9 13 5.5 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Destabilase PF05497.7 ETO26035.1 - 1.5e-06 28.2 3.6 1.6e-06 28.2 0.1 2.5 3 0 0 3 3 3 1 Destabilase Amidohydro_2 PF04909.9 ETO26036.1 - 1.2e-38 133.2 0.0 1.4e-38 133.0 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase Orthoreo_P17 PF07272.6 ETO26037.1 - 0.037 13.8 0.0 0.093 12.5 0.0 1.6 1 0 0 1 1 1 0 Orthoreovirus P17 protein TPR_11 PF13414.1 ETO26039.1 - 4.9e-15 54.9 24.2 5.8e-06 25.8 1.4 4.2 2 1 2 4 4 4 4 TPR repeat TPR_2 PF07719.12 ETO26039.1 - 7.5e-13 47.3 18.4 0.00082 19.1 1.1 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO26039.1 - 3.8e-11 42.1 19.0 0.00029 20.3 0.4 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO26039.1 - 2.1e-09 36.8 15.3 0.0022 18.0 0.2 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO26039.1 - 1.5e-07 30.6 17.9 0.027 14.2 0.6 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO26039.1 - 2.6e-07 31.1 4.7 0.00027 21.5 0.4 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO26039.1 - 2.7e-07 30.8 11.7 0.0016 18.7 0.1 4.1 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO26039.1 - 6.3e-07 29.2 19.6 0.0044 16.9 2.5 3.8 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO26039.1 - 1.4e-06 28.4 2.0 0.033 14.8 0.1 4.5 2 1 3 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO26039.1 - 1.5e-05 25.0 17.7 0.00091 19.3 6.4 2.8 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETO26039.1 - 0.0032 17.8 15.3 0.82 10.2 0.4 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_15 PF13429.1 ETO26039.1 - 0.0086 15.1 5.8 1.9 7.4 0.0 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETO26039.1 - 0.024 14.5 8.6 1.2 9.2 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETO26039.1 - 0.089 12.6 11.6 1.9 8.4 0.2 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat Helicase_C PF00271.26 ETO26040.1 - 3.6e-14 52.3 0.0 8.5e-14 51.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETO26041.1 - 1.1e-06 28.2 3.3 2.2e-05 24.0 0.1 2.9 3 1 0 3 3 3 2 DEAD/DEAH box helicase Snf7 PF03357.16 ETO26043.1 - 1.1e-18 67.1 27.1 1.1e-18 67.1 18.8 1.8 1 1 1 2 2 2 1 Snf7 Flavi_DEAD PF07652.9 ETO26043.1 - 0.013 15.3 0.5 0.013 15.3 0.3 1.7 2 0 0 2 2 2 0 Flavivirus DEAD domain MutS_III PF05192.13 ETO26043.1 - 0.099 12.4 6.4 0.17 11.6 4.5 1.3 1 0 0 1 1 1 0 MutS domain III DUF1108 PF06531.6 ETO26043.1 - 0.18 12.0 4.2 0.085 13.0 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1108) THP2 PF09432.5 ETO26043.1 - 0.29 11.0 13.3 0.45 10.3 1.1 3.2 1 1 1 3 3 3 0 Tho complex subunit THP2 Exonuc_VII_L PF02601.10 ETO26043.1 - 0.64 9.1 10.9 0.93 8.6 7.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Prefoldin_2 PF01920.15 ETO26043.1 - 2.3 8.0 25.5 2.4 7.9 2.4 3.7 2 1 0 3 3 3 0 Prefoldin subunit DUF342 PF03961.8 ETO26043.1 - 2.5 6.4 21.0 0.15 10.4 6.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF342) RPN7 PF10602.4 ETO26043.1 - 6 6.2 11.6 5.2 6.4 0.1 2.9 3 1 0 3 3 3 0 26S proteasome subunit RPN7 Hemerythrin PF01814.18 ETO26043.1 - 9.9 6.3 9.7 29 4.8 0.3 2.8 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain GlcNAc PF11397.3 ETO26044.1 - 0.0001 21.5 0.0 0.00013 21.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) Cullin_Nedd8 PF10557.4 ETO26047.1 - 2.8e-27 94.3 1.5 4.6e-27 93.6 1.1 1.4 1 0 0 1 1 1 1 Cullin protein neddylation domain Cullin PF00888.17 ETO26047.1 - 1.6e-06 26.9 1.0 1.9e-06 26.7 0.2 1.5 2 0 0 2 2 2 1 Cullin family Penicillinase_R PF03965.11 ETO26047.1 - 0.017 15.2 0.0 0.036 14.1 0.0 1.6 1 1 0 1 1 1 0 Penicillinase repressor GatB_Yqey PF02637.13 ETO26047.1 - 0.033 13.9 1.9 0.043 13.5 1.3 1.2 1 0 0 1 1 1 0 GatB domain AAA_18 PF13238.1 ETO26049.1 - 8.9e-10 38.9 0.0 1.3e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETO26049.1 - 9.6e-06 25.5 0.0 1.8e-05 24.6 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ETO26049.1 - 1.5e-05 25.8 0.0 2.5e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 ETO26049.1 - 0.00033 20.8 0.0 0.00064 19.9 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 ETO26049.1 - 0.0011 17.8 0.0 0.0023 16.8 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 ETO26049.1 - 0.0056 16.6 0.0 0.0091 15.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 ETO26049.1 - 0.011 15.8 0.0 0.019 15.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain Torsin PF06309.6 ETO26049.1 - 0.017 14.9 0.1 0.028 14.2 0.1 1.4 1 0 0 1 1 1 0 Torsin Arch_ATPase PF01637.13 ETO26049.1 - 0.04 13.5 0.3 0.1 12.2 0.1 1.7 1 1 1 2 2 2 0 Archaeal ATPase NACHT PF05729.7 ETO26049.1 - 0.049 13.2 0.3 0.11 12.2 0.2 2.0 1 1 0 1 1 1 0 NACHT domain RPAP3_C PF13877.1 ETO26049.1 - 0.053 13.4 0.9 0.13 12.2 0.1 2.0 2 1 0 2 2 2 0 Potential Monad-binding region of RPAP3 AAA_5 PF07728.9 ETO26049.1 - 0.065 12.9 0.1 0.58 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ADK PF00406.17 ETO26049.1 - 0.076 12.8 0.0 2.1 8.2 0.0 2.3 2 1 0 2 2 2 0 Adenylate kinase RNA_helicase PF00910.17 ETO26049.1 - 0.1 12.7 0.1 0.28 11.3 0.0 2.0 2 1 0 2 2 1 0 RNA helicase Zeta_toxin PF06414.7 ETO26049.1 - 0.13 11.3 0.0 0.79 8.7 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin Es2 PF09751.4 ETO26050.1 - 1.6e-50 172.7 20.9 1.6e-50 172.7 14.5 2.1 2 1 0 2 2 2 1 Nuclear protein Es2 SAM_1 PF00536.25 ETO26051.1 - 7.3e-08 32.4 0.2 1.4e-07 31.6 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO26051.1 - 1.1e-07 31.5 0.1 1.9e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF148 PF02520.12 ETO26051.1 - 0.0039 16.9 1.5 0.0091 15.7 1.1 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF148 Ndc80_HEC PF03801.8 ETO26051.1 - 0.004 16.5 0.6 0.004 16.5 0.4 1.8 2 0 0 2 2 2 1 HEC/Ndc80p family Colicin_M PF14859.1 ETO26052.1 - 0.051 12.4 0.0 0.12 11.2 0.0 1.6 1 1 1 2 2 2 0 Colicin M PIP5K PF01504.13 ETO26053.1 - 1.4e-30 106.2 0.0 3.1e-29 101.8 0.0 2.4 2 1 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF3870 PF12986.2 ETO26056.1 - 0.028 14.6 0.1 0.094 12.9 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) Toxin_52 PF15605.1 ETO26057.1 - 0.015 15.1 0.8 0.095 12.5 0.6 2.0 1 1 0 1 1 1 0 Putative toxin 52 IBN_N PF03810.14 ETO26057.1 - 0.095 12.6 1.0 0.2 11.5 0.1 2.0 1 1 1 2 2 2 0 Importin-beta N-terminal domain WD40 PF00400.27 ETO26058.1 - 1.3e-64 211.9 21.0 3e-12 45.9 0.1 7.2 6 1 1 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO26058.1 - 6.2e-05 21.3 6.5 0.22 9.5 0.6 4.2 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Str_synth PF03088.11 ETO26058.1 - 0.00049 20.0 0.2 7.2 6.7 0.0 4.3 2 2 2 4 4 4 1 Strictosidine synthase DUF1258 PF06869.7 ETO26058.1 - 0.0035 16.4 1.7 7.8 5.5 0.0 3.4 1 1 3 4 4 4 2 Protein of unknown function (DUF1258) Cytochrom_D1 PF02239.11 ETO26058.1 - 0.0088 14.3 0.2 2.8 6.1 0.0 3.5 3 1 1 4 4 4 1 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 ETO26058.1 - 0.014 14.7 6.0 2 7.7 0.0 5.4 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Resistin PF06954.6 ETO26058.1 - 0.016 15.4 5.5 39 4.6 0.0 4.4 3 2 2 5 5 5 0 Resistin SusE PF14292.1 ETO26058.1 - 0.018 14.8 0.0 3 7.6 0.0 2.9 3 1 0 3 3 3 0 SusE outer membrane protein PD40 PF07676.7 ETO26058.1 - 0.028 14.0 5.4 22 4.8 0.0 5.1 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Ricin_B_lectin PF00652.17 ETO26058.1 - 0.097 12.7 4.3 0.21 11.6 0.2 2.7 1 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain PLD_C PF12357.3 ETO26058.1 - 0.097 12.2 0.1 48 3.5 0.0 3.8 4 0 0 4 4 4 0 Phospholipase D C terminal CDC45 PF02724.9 ETO26059.1 - 0.069 11.1 23.8 0.0058 14.7 8.4 2.6 3 0 0 3 3 3 0 CDC45-like protein DUF1510 PF07423.6 ETO26059.1 - 0.78 9.0 36.1 0.83 8.9 18.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) DUF1509 PF07420.6 ETO26059.1 - 7.4 5.7 17.9 2.3 7.4 5.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1509) EF_assoc_1 PF08355.7 ETO26060.1 - 0.0086 15.3 0.1 0.017 14.3 0.0 1.5 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 ETO26061.1 - 8.8e-13 47.9 0.3 2.8e-12 46.3 0.0 2.1 1 1 0 1 1 1 1 Ras family Miro PF08477.8 ETO26061.1 - 8.6e-12 45.6 0.8 1.7e-11 44.6 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 ETO26061.1 - 0.0013 18.6 0.2 0.0034 17.3 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.13 ETO26061.1 - 0.0017 17.4 0.1 0.0017 17.4 0.0 1.9 2 0 0 2 2 2 1 Septin AAA_22 PF13401.1 ETO26061.1 - 0.007 16.5 0.0 0.15 12.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF2730 PF10805.3 ETO26061.1 - 0.0075 15.9 0.8 0.016 14.9 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2730) MobB PF03205.9 ETO26061.1 - 0.043 13.5 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 ETO26061.1 - 0.05 13.0 1.6 0.58 9.5 1.1 2.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 ETO26061.1 - 0.077 12.8 3.4 1.9 8.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 ETO26062.1 - 3.5e-08 33.9 0.3 1.5e-07 31.9 0.0 2.2 2 1 0 2 2 2 1 Miro-like protein Ras PF00071.17 ETO26062.1 - 0.00018 20.9 0.6 0.0018 17.7 0.4 2.2 1 1 0 1 1 1 1 Ras family AAA_24 PF13479.1 ETO26062.1 - 0.047 13.2 1.1 0.085 12.4 0.1 1.9 2 0 0 2 2 2 0 AAA domain CENP-M PF11111.3 ETO26062.1 - 0.066 12.4 1.0 1.2 8.3 0.1 2.6 2 1 0 2 2 2 0 Centromere protein M (CENP-M) MEF2_binding PF09047.5 ETO26062.1 - 0.084 12.5 2.3 0.34 10.5 1.6 2.0 1 0 0 1 1 1 0 MEF2 binding RGS PF00615.14 ETO26063.1 - 0.00011 22.2 0.1 0.00011 22.2 0.1 2.1 3 0 0 3 3 3 1 Regulator of G protein signaling domain GyrI-like PF06445.10 ETO26064.1 - 1.5e-11 44.5 0.0 3.1e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 GyrI-like small molecule binding domain Cass2 PF14526.1 ETO26064.1 - 0.0019 18.2 0.1 0.0049 16.8 0.0 1.7 1 0 0 1 1 1 1 Integron-associated effector binding protein Glyoxalase PF00903.20 ETO26064.1 - 0.0088 16.0 0.8 0.024 14.6 0.5 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 ETO26064.1 - 0.01 16.4 0.1 0.022 15.3 0.1 1.6 1 0 0 1 1 1 0 Glyoxalase-like domain TPR_11 PF13414.1 ETO26065.1 - 9.5e-06 25.1 2.4 9.5e-06 25.1 1.7 2.1 2 1 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 ETO26065.1 - 0.00012 21.7 0.4 0.3 11.0 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO26065.1 - 0.00041 19.8 1.6 0.43 10.2 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO26065.1 - 0.0029 17.6 2.3 2 8.7 0.0 2.8 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO26065.1 - 0.0046 16.6 0.9 0.97 9.3 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO26065.1 - 0.024 14.5 1.1 0.11 12.5 0.8 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETO26065.1 - 0.05 13.4 0.3 1.1 9.2 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Bestrophin PF01062.16 ETO26065.1 - 0.094 11.6 0.2 0.13 11.2 0.1 1.1 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel DDHD PF02862.12 ETO26065.1 - 0.32 10.7 6.5 0.34 10.6 4.5 1.2 1 0 0 1 1 1 0 DDHD domain AKAP7_RIRII_bdg PF10470.4 ETO26065.1 - 0.51 10.2 5.8 1.7 8.5 4.0 2.1 1 1 0 1 1 1 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein RP-C_C PF11800.3 ETO26065.1 - 2.6 7.7 8.3 4.3 6.9 5.7 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF1754 PF08555.5 ETO26065.1 - 8.5 7.0 18.6 1.5 9.4 10.5 1.6 2 0 0 2 2 1 0 Eukaryotic family of unknown function (DUF1754) TPR_11 PF13414.1 ETO26066.1 - 1.6e-14 53.3 0.4 4e-14 52.0 0.3 1.7 1 0 0 1 1 1 1 TPR repeat Rubis-subs-bind PF09273.6 ETO26066.1 - 1.5e-08 34.5 0.1 5.7e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.23 ETO26066.1 - 1.5e-08 35.0 0.0 1.5e-05 25.3 0.0 2.7 2 0 0 2 2 2 2 SET domain TPR_2 PF07719.12 ETO26066.1 - 6e-08 32.0 1.7 0.011 15.5 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO26066.1 - 8.7e-08 31.4 1.5 0.0049 16.4 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO26066.1 - 0.00013 22.2 0.1 0.29 11.8 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO26066.1 - 0.00015 22.2 0.5 0.00028 21.4 0.4 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO26066.1 - 0.02 14.8 0.6 0.055 13.4 0.4 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETO26066.1 - 0.021 14.5 0.6 5.5 7.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 ETO26066.1 - 0.095 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Nop14 PF04147.7 ETO26067.1 - 0.017 13.1 9.6 0.027 12.4 6.7 1.3 1 0 0 1 1 1 0 Nop14-like family Tim54 PF11711.3 ETO26067.1 - 0.053 12.1 3.4 0.084 11.4 2.3 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PASTA PF03793.14 ETO26067.1 - 0.06 12.9 0.6 0.06 12.9 0.4 1.6 2 0 0 2 2 2 0 PASTA domain TRAP_alpha PF03896.11 ETO26067.1 - 0.7 8.8 5.0 1.1 8.2 3.4 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2890 PF11081.3 ETO26067.1 - 0.92 9.5 12.9 1.5 8.8 9.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) RRM_1 PF00076.17 ETO26068.1 - 6.5e-14 51.3 0.0 4.8e-13 48.5 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO26068.1 - 5.7e-13 48.5 0.1 3.9e-11 42.6 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO26068.1 - 1.5e-09 37.6 0.1 4.8e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2024 PF09630.5 ETO26069.1 - 0.074 12.7 0.3 0.19 11.4 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) DUF4551 PF15087.1 ETO26069.1 - 3 6.0 13.4 3.8 5.7 9.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Glyco_tran_28_C PF04101.11 ETO26069.1 - 3.2 7.3 8.2 0.1 12.2 0.4 2.3 1 1 1 2 2 2 0 Glycosyltransferase family 28 C-terminal domain SieB PF14163.1 ETO26069.1 - 9.4 5.7 10.8 2.3 7.7 0.2 2.9 2 1 1 3 3 3 0 Superinfection exclusion protein B tRNA_edit PF04073.10 ETO26070.1 - 6.6e-12 45.3 0.0 1.1e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain zf-UBR PF02207.15 ETO26070.1 - 0.25 11.0 0.1 0.25 11.0 0.1 2.8 3 1 0 3 3 3 0 Putative zinc finger in N-recognin (UBR box) DUF645 PF04875.7 ETO26070.1 - 0.44 10.2 3.2 0.19 11.4 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF645 PrsW-protease PF13367.1 ETO26071.1 - 2.2e-13 49.8 14.4 6e-13 48.4 10.2 1.6 1 1 0 1 1 1 1 Protease prsW family DUF2324 PF10086.4 ETO26071.1 - 7.7e-06 25.2 6.3 1.2e-05 24.6 0.5 3.0 1 1 2 3 3 3 1 Putative membrane peptidase family (DUF2324) DUF843 PF05814.6 ETO26071.1 - 3.5 7.4 5.4 5.5 6.8 1.1 2.5 2 1 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) GST_C PF00043.20 ETO26072.1 - 3.8e-07 29.9 0.1 6e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 ETO26072.1 - 9e-05 22.5 0.0 0.0011 19.0 0.0 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 ETO26072.1 - 0.00024 21.5 0.0 0.00064 20.1 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETO26072.1 - 0.0029 17.4 0.0 0.02 14.7 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain RhoGEF PF00621.15 ETO26072.1 - 0.013 15.4 0.7 0.018 14.9 0.5 1.2 1 0 0 1 1 1 0 RhoGEF domain Vps26 PF03643.10 ETO26073.1 - 1.9e-99 331.8 0.5 2.4e-99 331.5 0.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_C PF02752.17 ETO26073.1 - 0.05 13.7 0.8 1.6 8.8 0.1 2.5 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain BSP_II PF05432.6 ETO26074.1 - 0.047 12.9 11.7 0.046 13.0 8.1 1.0 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) FAM176 PF14851.1 ETO26074.1 - 0.047 13.3 4.9 0.043 13.4 3.4 1.0 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.1 ETO26074.1 - 0.061 13.6 5.8 0.067 13.5 4.0 1.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1754 PF08555.5 ETO26074.1 - 0.12 12.9 8.2 0.13 12.8 5.7 1.0 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Myc_N PF01056.13 ETO26074.1 - 0.16 11.1 6.1 0.15 11.1 4.2 1.0 1 0 0 1 1 1 0 Myc amino-terminal region DUF573 PF04504.9 ETO26074.1 - 0.26 11.5 3.7 0.28 11.4 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF573 RXT2_N PF08595.6 ETO26074.1 - 0.27 11.0 5.8 0.31 10.8 4.0 1.0 1 0 0 1 1 1 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 ETO26074.1 - 0.29 10.6 8.7 0.31 10.5 6.0 1.1 1 0 0 1 1 1 0 Nucleoplasmin Pox_Ag35 PF03286.9 ETO26074.1 - 0.72 9.3 9.0 0.73 9.3 6.2 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CLPTM1 PF05602.7 ETO26074.1 - 1.1 7.9 5.6 1 7.9 3.9 1.0 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) BLVR PF06375.6 ETO26074.1 - 1.1 9.1 9.0 1.2 8.9 6.2 1.0 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) RNA_pol_3_Rpc31 PF11705.3 ETO26074.1 - 1.4 8.8 10.2 1.2 8.9 7.0 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.5 ETO26074.1 - 1.4 9.2 6.5 1.4 9.1 4.5 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain BTV_NS2 PF04514.7 ETO26074.1 - 1.4 7.6 6.9 1.4 7.6 4.8 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 MscS_TM PF12794.2 ETO26074.1 - 1.9 7.0 6.8 1.9 7.0 4.7 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF2457 PF10446.4 ETO26074.1 - 2.4 6.7 13.0 2.2 6.8 9.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Adeno_terminal PF02459.10 ETO26074.1 - 5.1 5.1 6.1 4.6 5.2 4.2 1.0 1 0 0 1 1 1 0 Adenoviral DNA terminal protein PBP_sp32 PF07222.7 ETO26074.1 - 5.5 6.0 10.6 5.3 6.1 7.3 1.0 1 0 0 1 1 1 0 Proacrosin binding protein sp32 RGS PF00615.14 ETO26075.1 - 0.00024 21.1 0.2 0.00048 20.2 0.1 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain MRI PF15325.1 ETO26077.1 - 2.3 9.2 15.8 1.7 9.6 3.5 2.3 2 0 0 2 2 2 0 Modulator of retrovirus infection DUF1510 PF07423.6 ETO26077.1 - 9.6 5.5 30.8 4.3 6.6 3.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) MIP-T3 PF10243.4 ETO26078.1 - 0.76 8.1 45.5 1.1 7.6 31.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Cytochrom_C PF00034.16 ETO26080.1 - 1.2e-11 45.2 0.4 3.6e-08 34.1 0.4 2.1 2 0 0 2 2 2 2 Cytochrome c Cytochrome_CBB3 PF13442.1 ETO26080.1 - 2.5e-09 37.1 0.6 1.1e-05 25.4 0.3 2.1 2 0 0 2 2 2 2 Cytochrome C oxidase, cbb3-type, subunit III CCP_MauG PF03150.9 ETO26080.1 - 0.0032 17.7 0.0 0.0038 17.5 0.0 1.1 1 0 0 1 1 1 1 Di-haem cytochrome c peroxidase Cytochrom_C550 PF14495.1 ETO26080.1 - 0.013 14.9 0.3 0.025 14.0 0.2 1.4 1 0 0 1 1 1 0 Cytochrome c-550 domain Cytochrom_C1 PF02167.10 ETO26080.1 - 0.074 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C1 family Ras PF00071.17 ETO26081.1 - 7.4e-33 113.2 0.1 1e-32 112.7 0.1 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO26081.1 - 2.4e-11 44.1 0.0 2.8e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO26081.1 - 2.2e-08 33.5 0.1 2.5e-08 33.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Archaeal_AmoA PF12942.2 ETO26082.1 - 0.079 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Archaeal ammonia monooxygenase subunit A (AmoA) DSX_dimer PF08828.5 ETO26082.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Doublesex dimerisation domain TPX2_importin PF12214.3 ETO26084.1 - 1.6e-06 28.2 1.7 1.6e-06 28.2 1.2 2.4 2 0 0 2 2 2 1 Cell cycle regulated microtubule associated protein TPR_11 PF13414.1 ETO26085.1 - 1.7e-17 62.8 16.6 3.8e-08 32.8 0.4 5.0 3 1 2 5 5 5 4 TPR repeat TPR_12 PF13424.1 ETO26085.1 - 3.6e-14 52.4 11.4 5.5e-07 29.4 0.3 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO26085.1 - 8.2e-13 47.3 9.9 0.0086 15.6 0.0 6.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO26085.1 - 7.6e-12 44.1 16.4 0.029 14.2 0.0 6.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO26085.1 - 2e-10 40.3 0.4 0.054 14.1 0.2 5.6 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO26085.1 - 2.2e-10 40.7 0.2 9.3e-05 22.6 0.0 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO26085.1 - 3.2e-10 39.3 3.8 0.044 14.0 0.1 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO26085.1 - 5.8e-10 38.2 7.8 0.0096 15.6 0.0 5.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO26085.1 - 1.3e-09 38.4 1.9 0.00058 20.4 0.1 3.5 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETO26085.1 - 3e-07 30.1 3.1 0.014 15.2 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO26085.1 - 1.8e-05 24.7 14.4 0.01 15.9 2.8 3.6 2 2 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 ETO26085.1 - 0.00037 19.6 0.0 0.24 10.6 0.0 2.9 3 0 0 3 3 3 2 SHNi-TPR TPR_6 PF13174.1 ETO26085.1 - 0.00082 19.6 6.8 0.73 10.4 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO26085.1 - 0.014 15.1 6.5 4 7.4 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 ETO26085.1 - 0.027 14.5 0.0 0.94 9.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 ETO26085.1 - 0.12 12.3 4.8 27 4.8 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat PX PF00787.19 ETO26086.1 - 1.6e-20 72.9 0.3 3.3e-20 71.9 0.2 1.5 1 0 0 1 1 1 1 PX domain PDZ PF00595.19 ETO26086.1 - 0.00057 19.9 0.0 0.0014 18.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) WD40 PF00400.27 ETO26087.1 - 1.8e-54 179.7 24.3 1.5e-11 43.7 1.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat zf-TRAF PF02176.13 ETO26087.1 - 2.3e-05 24.6 3.3 2.3e-05 24.6 2.3 2.5 3 0 0 3 3 3 1 TRAF-type zinc finger Kinesin PF00225.18 ETO26088.1 - 1.9e-24 85.9 0.0 2e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain DUF3141 PF11339.3 ETO26088.1 - 0.0059 14.9 0.0 0.0073 14.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3141) DUF4545 PF15078.1 ETO26088.1 - 0.011 14.7 0.0 2.1 7.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4545) T2SE PF00437.15 ETO26088.1 - 0.024 13.5 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Bac_DnaA PF00308.13 ETO26088.1 - 0.064 12.8 0.4 0.13 11.8 0.1 1.6 1 1 1 2 2 2 0 Bacterial dnaA protein AAA_22 PF13401.1 ETO26088.1 - 0.15 12.2 0.3 0.57 10.3 0.2 1.9 1 1 1 2 2 2 0 AAA domain Kelch_2 PF07646.10 ETO26090.1 - 0.0033 17.1 1.5 6.9 6.6 0.1 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO26090.1 - 0.016 15.3 1.2 7 7.0 0.0 3.5 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.1 ETO26090.1 - 0.075 12.8 0.3 0.73 9.6 0.1 2.7 3 0 0 3 3 3 0 Galactose oxidase, central domain Chromo PF00385.19 ETO26091.1 - 0.0021 17.6 0.1 0.0051 16.4 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain FimP PF09766.4 ETO26091.1 - 0.027 13.5 5.4 0.035 13.1 3.7 1.1 1 0 0 1 1 1 0 Fms-interacting protein DUF912 PF06024.7 ETO26091.1 - 0.53 10.3 2.2 0.33 11.0 0.2 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Gal-3-0_sulfotr PF06990.6 ETO26092.1 - 0.00036 19.3 7.8 0.0041 15.8 5.4 2.1 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase PPR_2 PF13041.1 ETO26093.1 - 6.3e-15 54.8 3.3 1.8e-10 40.6 0.4 4.3 3 1 2 5 5 5 2 PPR repeat family PPR_3 PF13812.1 ETO26093.1 - 2.2e-11 43.1 0.1 0.0042 17.2 0.0 4.6 4 1 0 4 4 4 3 Pentatricopeptide repeat domain PPR PF01535.15 ETO26093.1 - 2.7e-09 36.3 7.6 3.5e-05 23.4 0.1 4.8 6 0 0 6 6 6 2 PPR repeat PPR_1 PF12854.2 ETO26093.1 - 2.9e-05 23.4 0.3 0.0071 15.7 0.0 3.9 5 0 0 5 5 5 1 PPR repeat TPR_19 PF14559.1 ETO26093.1 - 0.00027 21.2 0.0 0.44 10.9 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat Vps39_1 PF10366.4 ETO26093.1 - 0.0015 18.5 1.8 0.69 9.9 0.0 3.3 1 1 1 2 2 2 1 Vacuolar sorting protein 39 domain 1 TPR_11 PF13414.1 ETO26093.1 - 0.0033 17.0 0.4 1.3 8.7 0.0 2.9 2 0 0 2 2 2 2 TPR repeat ECSIT PF06239.6 ETO26093.1 - 0.0075 15.1 0.4 4.5 6.0 0.1 3.2 2 1 2 4 4 4 2 Evolutionarily conserved signalling intermediate in Toll pathway Apc3 PF12895.2 ETO26093.1 - 0.032 14.3 1.2 0.42 10.7 0.6 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Alpha-2-MRAP_C PF06401.6 ETO26093.1 - 0.12 12.2 5.6 3.5 7.4 0.6 2.8 2 1 1 3 3 3 0 Alpha-2-macroglobulin RAP, C-terminal domain DUF2361 PF10153.4 ETO26094.1 - 7.5 6.7 9.1 2.4 8.3 1.9 2.5 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2361) DENN PF02141.16 ETO26095.1 - 3.3e-15 56.2 0.0 6.8e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain SPA PF08616.5 ETO26095.1 - 0.00038 20.1 0.4 0.00087 18.9 0.3 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis Sporozoite_P67 PF05642.6 ETO26095.1 - 0.15 9.9 16.3 0.28 8.9 11.3 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SSP160 PF06933.6 ETO26095.1 - 6.4 4.6 20.0 9.3 4.0 13.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Kelch_4 PF13418.1 ETO26097.1 - 1e-07 31.6 0.1 0.0015 18.2 0.0 3.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO26097.1 - 0.0005 20.1 0.0 0.04 14.0 0.0 3.1 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO26097.1 - 0.0027 17.6 0.2 5.7 7.0 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO26097.1 - 0.011 15.8 0.9 21 5.4 0.0 3.9 3 1 1 4 4 4 0 Kelch motif Kelch_1 PF01344.20 ETO26097.1 - 0.054 13.0 0.6 0.52 9.8 0.0 2.9 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.10 ETO26097.1 - 0.065 13.0 1.1 1.7 8.5 0.0 3.4 4 0 0 4 4 4 0 Kelch motif Transketolase_C PF02780.15 ETO26098.1 - 0.00028 20.8 0.0 0.00049 20.0 0.0 1.5 1 1 0 1 1 1 1 Transketolase, C-terminal domain Nsp1_C PF05064.8 ETO26099.1 - 6.8e-18 64.4 20.2 2.7e-17 62.5 5.9 2.9 3 0 0 3 3 3 2 Nsp1-like C-terminal region Nuf2 PF03800.9 ETO26099.1 - 0.0028 17.6 0.4 0.0066 16.4 0.3 1.7 1 0 0 1 1 1 1 Nuf2 family Baculo_PEP_C PF04513.7 ETO26099.1 - 0.038 13.7 10.1 0.067 13.0 2.4 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ASL_C PF08328.6 ETO26099.1 - 0.069 13.0 4.3 2.2 8.1 0.4 2.7 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminal Reo_sigmaC PF04582.7 ETO26099.1 - 1.1 8.4 4.8 5.8 5.9 0.2 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF1777 PF08648.7 ETO26099.1 - 5.8 6.5 18.0 1.2 8.8 4.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) RGS PF00615.14 ETO26100.1 - 0.0033 17.5 0.4 0.0053 16.8 0.3 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain Methyltransf_16 PF10294.4 ETO26101.1 - 6.7e-11 41.9 0.0 1.2e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 ETO26101.1 - 0.0005 19.2 0.6 0.0014 17.7 0.4 1.8 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 ETO26101.1 - 0.0052 17.3 0.0 0.02 15.4 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.9 ETO26101.1 - 0.028 13.8 0.0 0.071 12.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain TMEM154 PF15102.1 ETO26102.1 - 0.0044 16.7 0.2 0.0067 16.1 0.1 1.3 1 0 0 1 1 1 1 TMEM154 protein family DUF4252 PF14060.1 ETO26103.1 - 0.1 12.1 0.2 0.1 12.1 0.1 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4252) Thioredoxin PF00085.15 ETO26105.1 - 7.3e-52 173.4 3.3 2.4e-25 88.2 0.0 5.8 5 1 0 5 5 5 4 Thioredoxin WD40 PF00400.27 ETO26105.1 - 5.3e-44 146.5 22.2 5.5e-10 38.7 1.0 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Thioredoxin_2 PF13098.1 ETO26105.1 - 9.2e-08 32.2 16.6 0.0015 18.7 0.3 5.1 5 1 0 5 5 5 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 ETO26105.1 - 4.9e-07 29.7 3.9 1.6 8.9 0.0 5.4 3 1 1 4 4 4 3 Thioredoxin-like Thioredoxin_3 PF13192.1 ETO26105.1 - 4.4e-05 23.1 0.7 0.22 11.3 0.0 3.6 3 0 0 3 3 3 2 Thioredoxin domain Thioredoxin_7 PF13899.1 ETO26105.1 - 0.00019 21.4 0.3 0.033 14.2 0.0 3.0 3 0 0 3 3 3 1 Thioredoxin-like Pkinase PF00069.20 ETO26108.1 - 9.6e-08 31.4 1.2 4.5e-07 29.2 0.9 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO26108.1 - 7.1e-07 28.5 1.9 0.00012 21.2 1.3 3.2 1 1 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.25 ETO26109.1 - 9.8e-11 41.3 4.6 4.4e-10 39.2 3.2 2.2 1 1 0 1 1 1 1 C2 domain FlaC_arch PF05377.6 ETO26109.1 - 0.00043 20.1 2.2 0.00043 20.1 1.5 8.3 5 4 4 9 9 9 1 Flagella accessory protein C (FlaC) CALCOCO1 PF07888.6 ETO26109.1 - 0.00063 18.1 6.6 0.00063 18.1 4.5 3.2 1 1 2 3 3 3 2 Calcium binding and coiled-coil domain (CALCOCO1) like Reo_sigmaC PF04582.7 ETO26109.1 - 0.00085 18.5 31.9 0.06 12.5 8.0 4.0 2 1 2 4 4 4 2 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 ETO26109.1 - 0.0013 16.5 85.0 0.016 13.0 3.2 3.3 3 1 0 3 3 3 2 Myosin tail GAS PF13851.1 ETO26109.1 - 0.0028 16.8 89.2 0.017 14.3 15.2 5.4 3 1 2 5 5 5 3 Growth-arrest specific micro-tubule binding DUF904 PF06005.7 ETO26109.1 - 0.0091 16.2 6.4 0.0091 16.2 4.4 8.5 3 1 2 5 5 3 2 Protein of unknown function (DUF904) Nup54 PF13874.1 ETO26109.1 - 0.01 15.5 24.4 0.01 15.5 16.9 4.8 3 1 2 5 5 5 0 Nucleoporin complex subunit 54 CENP-F_leu_zip PF10473.4 ETO26109.1 - 0.016 15.0 93.1 0.041 13.7 3.7 6.1 3 1 3 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.8 ETO26109.1 - 0.029 14.7 4.1 0.029 14.7 2.8 7.3 3 1 4 7 7 6 0 Protein of unknown function (DUF972) DUF4497 PF14924.1 ETO26109.1 - 0.052 13.8 0.1 0.052 13.8 0.1 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF4497) APG6 PF04111.7 ETO26109.1 - 3.4 6.6 94.9 0.12 11.3 19.3 5.0 3 1 2 5 5 5 0 Autophagy protein Apg6 ATG16 PF08614.6 ETO26109.1 - 4.2 7.1 92.1 0.25 11.1 11.9 4.9 2 2 2 4 4 4 0 Autophagy protein 16 (ATG16) Alpha-mann_mid PF09261.6 ETO26110.1 - 1.1e-23 83.1 0.0 2.6e-23 82.0 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Glyco_hydro_38C PF07748.8 ETO26110.1 - 2.4e-09 36.5 0.0 4.7e-09 35.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain DUF1957 PF09210.6 ETO26110.1 - 0.11 12.5 0.0 6.4 6.9 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1957) ubiquitin PF00240.18 ETO26112.1 - 6e-05 22.3 2.8 0.44 9.9 0.1 3.3 2 1 1 3 3 3 3 Ubiquitin family WD40 PF00400.27 ETO26113.1 - 5.5e-10 38.7 1.3 6.1e-06 25.9 0.1 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat YMF19 PF02326.10 ETO26114.1 - 0.16 12.5 0.3 0.16 12.5 0.2 4.5 2 2 2 5 5 5 0 Plant ATP synthase F0 Menin PF05053.8 ETO26114.1 - 1.4 7.0 9.6 2 6.4 6.7 1.2 1 0 0 1 1 1 0 Menin Ferric_reduct PF01794.14 ETO26116.1 - 7.6e-09 35.7 10.1 2.7e-08 33.9 7.0 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 ETO26116.1 - 2.3e-07 30.6 0.0 5.5e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain DUF4405 PF14358.1 ETO26116.1 - 0.0018 18.3 0.4 0.0018 18.3 0.3 3.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4405) DUF1435 PF07256.7 ETO26116.1 - 0.61 10.1 6.0 0.4 10.7 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) DUF1777 PF08648.7 ETO26118.1 - 0.0053 16.5 19.8 0.0066 16.1 13.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) Zip PF02535.17 ETO26118.1 - 0.49 9.3 1.6 3 6.7 0.5 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter Neur_chan_memb PF02932.11 ETO26118.1 - 3.6 7.4 6.0 5.3 6.8 4.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF365 PF04033.7 ETO26119.1 - 0.044 13.7 0.7 0.086 12.8 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF365) DUF1409 PF07197.7 ETO26120.1 - 0.0038 17.2 0.9 0.1 12.6 0.1 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1409) DUF3543 PF12063.3 ETO26120.1 - 0.0053 16.0 0.3 0.007 15.6 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) ALIX_LYPXL_bnd PF13949.1 ETO26120.1 - 0.0068 15.3 2.6 0.0079 15.1 1.8 1.1 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF342 PF03961.8 ETO26120.1 - 0.011 14.2 1.4 0.012 14.0 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Spc42p PF11544.3 ETO26120.1 - 0.012 15.4 0.2 0.029 14.3 0.2 1.6 1 0 0 1 1 1 0 Spindle pole body component Spc42p PRD_Mga PF08270.6 ETO26120.1 - 0.023 13.9 0.2 1.1 8.5 0.0 2.2 1 1 0 2 2 2 0 M protein trans-acting positive regulator (MGA) PRD domain Flavi_NS5 PF00972.15 ETO26120.1 - 0.029 12.2 0.4 0.034 12.0 0.3 1.0 1 0 0 1 1 1 0 Flavivirus RNA-directed RNA polymerase DUF4168 PF13767.1 ETO26120.1 - 0.032 14.8 0.3 0.066 13.8 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4168) Spore_YhaL PF14147.1 ETO26120.1 - 0.038 13.4 0.1 0.038 13.4 0.1 1.9 2 0 0 2 2 2 0 Sporulation protein YhaL Med28 PF11594.3 ETO26120.1 - 0.06 13.5 6.4 1 9.6 4.4 2.2 1 1 0 1 1 1 0 Mediator complex subunit 28 Syntaxin PF00804.20 ETO26120.1 - 0.063 13.4 2.2 0.096 12.8 1.5 1.2 1 0 0 1 1 1 0 Syntaxin DUF3829 PF12889.2 ETO26120.1 - 0.081 12.0 0.8 0.1 11.7 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) TBPIP PF07106.8 ETO26120.1 - 0.25 10.8 3.0 0.38 10.2 2.1 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 ETO26120.1 - 1.4 8.4 6.1 1.9 8.0 4.3 1.2 1 0 0 1 1 1 0 IncA protein SPX PF03105.14 ETO26121.1 - 0.017 14.9 10.0 0.025 14.3 6.9 1.2 1 0 0 1 1 1 0 SPX domain DUF3639 PF12341.3 ETO26122.1 - 0.00015 21.7 0.0 0.00049 20.0 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3639) WD40 PF00400.27 ETO26122.1 - 0.0074 16.1 1.8 33 4.5 0.0 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat RabGAP-TBC PF00566.13 ETO26123.1 - 4e-30 104.8 0.2 4e-30 104.8 0.2 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain NYD-SP28_assoc PF14775.1 ETO26123.1 - 0.017 14.8 0.2 0.048 13.3 0.1 1.8 1 0 0 1 1 1 0 Sperm tail C-terminal domain UCH PF00443.24 ETO26124.1 - 2.7e-75 252.9 0.0 5.5e-75 251.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 ETO26124.1 - 1.8e-19 69.9 0.9 1.1e-18 67.4 0.6 2.5 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.1 ETO26124.1 - 1.6e-17 63.8 0.0 7.1e-10 38.8 0.0 3.0 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Tudor-knot PF11717.3 ETO26124.1 - 0.032 13.9 2.4 0.27 10.9 1.6 2.5 1 1 0 1 1 1 0 RNA binding activity-knot of a chromodomain CENP-Q PF13094.1 ETO26125.1 - 0.02 14.9 1.0 0.035 14.1 0.7 1.3 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit YMF19 PF02326.10 ETO26125.1 - 1.8 9.2 7.0 0.37 11.3 1.2 2.2 1 1 1 2 2 2 0 Plant ATP synthase F0 zf-H2C2_2 PF13465.1 ETO26126.1 - 3.3e-15 55.5 17.8 1.3e-10 41.0 0.9 3.8 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 ETO26126.1 - 8.4e-12 44.7 20.4 0.00013 22.0 0.9 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETO26126.1 - 7.9e-08 32.1 16.2 0.011 16.0 1.3 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 ETO26126.1 - 5e-06 26.2 13.6 0.023 14.5 0.4 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 ETO26126.1 - 0.0025 17.9 1.1 0.0025 17.9 0.7 4.0 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 ETO26126.1 - 0.0029 17.5 9.9 0.5 10.3 0.2 3.4 3 0 0 3 3 3 2 Zinc ribbon domain zf-BED PF02892.10 ETO26126.1 - 0.0088 15.7 20.6 0.068 12.9 1.1 3.6 1 1 2 3 3 3 2 BED zinc finger zf-CHCC PF10276.4 ETO26126.1 - 0.046 13.5 0.4 0.046 13.5 0.3 2.8 3 0 0 3 3 3 0 Zinc-finger domain DZR PF12773.2 ETO26126.1 - 0.77 9.6 6.4 19 5.1 4.5 2.4 1 1 0 1 1 1 0 Double zinc ribbon zf-trcl PF13451.1 ETO26126.1 - 0.92 9.1 6.1 9.1 6.0 1.0 2.5 2 1 0 2 2 2 0 Probable zinc-binding domain zf-met PF12874.2 ETO26126.1 - 0.99 9.6 15.4 0.4 10.9 0.8 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Zn_Tnp_IS1595 PF12760.2 ETO26126.1 - 3.8 7.4 13.5 11 5.9 0.4 3.0 2 1 0 2 2 2 0 Transposase zinc-ribbon domain FYVE_2 PF02318.11 ETO26126.1 - 3.9 7.3 6.5 14 5.6 4.5 1.8 1 1 0 1 1 1 0 FYVE-type zinc finger DNA_RNApol_7kD PF03604.8 ETO26126.1 - 5.4 6.5 7.0 18 4.8 0.1 3.2 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Transp_Tc5_C PF04236.10 ETO26127.1 - 0.021 15.0 0.7 0.067 13.4 0.5 1.8 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain TT_ORF2 PF02957.10 ETO26128.1 - 0.0037 17.9 0.7 0.0049 17.5 0.5 1.3 1 0 0 1 1 1 1 TT viral ORF2 RNA_pol_3_Rpc31 PF11705.3 ETO26128.1 - 0.0056 16.6 7.5 0.0092 15.9 5.2 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Ribosomal_60s PF00428.14 ETO26128.1 - 0.2 12.0 5.9 0.1 13.0 2.5 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Pox_Ag35 PF03286.9 ETO26128.1 - 0.31 10.5 8.6 0.36 10.3 5.9 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2457 PF10446.4 ETO26128.1 - 1.1 7.8 13.3 1.3 7.6 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Trypan_PARP PF05887.6 ETO26128.1 - 2.4 7.9 8.2 2.6 7.8 5.7 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) IBR PF01485.16 ETO26130.1 - 4e-05 23.4 13.0 0.00033 20.4 2.5 3.4 3 2 0 3 3 3 2 IBR domain Neur_chan_memb PF02932.11 ETO26131.1 - 0.22 11.3 7.5 0.44 10.3 5.2 1.6 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Macoilin PF09726.4 ETO26132.1 - 0.11 10.8 29.0 0.14 10.4 20.1 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF605 PF04652.11 ETO26132.1 - 0.31 10.3 23.8 0.42 9.9 16.5 1.2 1 0 0 1 1 1 0 Vta1 like MIP-T3 PF10243.4 ETO26132.1 - 0.53 8.6 30.3 0.74 8.2 21.0 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 BTV_NS2 PF04514.7 ETO26132.1 - 2.1 7.1 14.4 3.6 6.3 10.0 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Peptidase_S64 PF08192.6 ETO26132.1 - 6.2 5.0 24.1 1.8 6.7 14.9 1.3 2 0 0 2 2 2 0 Peptidase family S64 DUF572 PF04502.8 ETO26132.1 - 8.7 5.4 30.8 16 4.5 21.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4337 PF14235.1 ETO26134.1 - 0.086 12.6 2.0 0.13 12.1 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF1510 PF07423.6 ETO26134.1 - 0.14 11.5 11.6 0.16 11.3 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Zip PF02535.17 ETO26134.1 - 0.14 11.1 1.9 0.18 10.7 1.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SDA1 PF05285.7 ETO26134.1 - 0.17 11.1 11.8 0.2 10.9 8.2 1.1 1 0 0 1 1 1 0 SDA1 DUF913 PF06025.7 ETO26134.1 - 0.18 10.5 1.8 0.21 10.3 1.2 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Neur_chan_memb PF02932.11 ETO26134.1 - 0.27 11.0 2.3 0.31 10.8 1.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Cwf_Cwc_15 PF04889.7 ETO26134.1 - 0.51 10.0 14.1 0.64 9.6 9.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Prog_receptor PF02161.10 ETO26134.1 - 2.7 6.7 5.7 3.4 6.3 4.0 1.1 1 0 0 1 1 1 0 Progesterone receptor IncA PF04156.9 ETO26134.1 - 3.2 7.2 5.5 4 6.9 3.8 1.2 1 0 0 1 1 1 0 IncA protein Sec62 PF03839.11 ETO26134.1 - 3.8 6.8 5.9 4.9 6.4 4.1 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Cnd1_N PF12922.2 ETO26135.1 - 2.4e-07 30.5 0.1 2.6e-06 27.1 0.0 2.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term DUF843 PF05814.6 ETO26135.1 - 0.011 15.4 0.2 0.045 13.5 0.2 2.0 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) Neurochondrin PF05536.6 ETO26135.1 - 0.014 13.7 0.0 0.019 13.3 0.0 1.3 1 1 0 1 1 1 0 Neurochondrin UPF0114 PF03350.11 ETO26135.1 - 0.027 14.3 0.5 0.073 12.9 0.3 1.6 1 0 0 1 1 1 0 Uncharacterized protein family, UPF0114 PsbH PF00737.15 ETO26135.1 - 0.22 11.1 1.2 0.46 10.1 0.8 1.5 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein GAPT PF11770.3 ETO26136.1 - 0.032 13.9 0.8 0.061 12.9 0.5 1.5 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) LRR_6 PF13516.1 ETO26136.1 - 0.36 11.0 4.6 0.46 10.7 0.1 3.3 2 1 1 3 3 3 0 Leucine Rich repeat CTD PF12815.2 ETO26137.1 - 0.0096 16.3 1.6 0.013 15.9 1.1 1.2 1 0 0 1 1 1 1 Spt5 C-terminal nonapeptide repeat binding Spt4 SEEEED PF14797.1 ETO26137.1 - 0.072 13.2 10.2 0.11 12.6 7.0 1.3 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex Pkinase PF00069.20 ETO26138.1 - 8e-49 166.1 0.1 1.1e-48 165.6 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO26138.1 - 1.4e-26 93.1 0.0 2.1e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO26138.1 - 1.4e-05 24.2 0.0 2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETO26138.1 - 4.8e-05 22.5 0.1 9e-05 21.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 ETO26138.1 - 0.032 13.5 0.0 0.06 12.6 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Cas_GSU0053 PF09617.5 ETO26138.1 - 0.16 11.7 0.2 0.27 11.0 0.2 1.3 1 0 0 1 1 1 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) Pkinase PF00069.20 ETO26139.1 - 1.9e-12 46.9 0.8 3.6e-12 45.9 0.6 1.4 1 0 0 1 1 1 1 Protein kinase domain PH PF00169.24 ETO26139.1 - 4.8e-09 36.3 0.6 4.8e-09 36.3 0.4 1.9 2 1 0 2 2 2 1 PH domain Pkinase_Tyr PF07714.12 ETO26139.1 - 5.1e-07 29.0 0.1 1e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PH_11 PF15413.1 ETO26139.1 - 1.1 9.5 9.3 1.5 9.1 0.8 3.6 2 1 1 3 3 3 0 Pleckstrin homology domain ubiquitin PF00240.18 ETO26140.1 - 1.8e-19 68.8 0.0 2.8e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 ETO26140.1 - 4e-11 42.4 0.0 6.2e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 ETO26140.1 - 0.00011 22.2 0.0 0.00018 21.6 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 ETO26140.1 - 0.00077 19.3 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Telomere_Sde2 PF13019.1 ETO26140.1 - 0.019 14.6 0.0 0.027 14.1 0.0 1.1 1 0 0 1 1 1 0 Telomere stability and silencing SNARE PF05739.14 ETO26141.1 - 1.9e-13 49.8 0.5 3.7e-13 48.9 0.3 1.5 1 0 0 1 1 1 1 SNARE domain Sec34 PF04136.10 ETO26141.1 - 0.0063 16.2 0.8 0.0095 15.6 0.5 1.3 1 0 0 1 1 1 1 Sec34-like family RasGAP_C PF03836.10 ETO26141.1 - 0.0096 15.6 1.9 0.0096 15.6 1.3 2.0 2 0 0 2 2 2 1 RasGAP C-terminus CHASE3 PF05227.8 ETO26141.1 - 0.059 13.0 0.8 1.4 8.6 0.3 2.1 1 1 1 2 2 2 0 CHASE3 domain Laminin_II PF06009.7 ETO26141.1 - 0.25 11.1 2.1 6.1 6.5 0.3 2.1 1 1 1 2 2 2 0 Laminin Domain II FliJ PF02050.11 ETO26141.1 - 4.8 7.2 7.5 0.87 9.6 2.3 1.8 2 0 0 2 2 2 0 Flagellar FliJ protein WD40 PF00400.27 ETO26142.1 - 6.1e-62 203.4 17.4 1.1e-12 47.2 0.0 7.8 8 1 0 8 8 8 7 WD domain, G-beta repeat PD40 PF07676.7 ETO26142.1 - 7.4e-09 35.0 1.5 0.68 9.6 0.0 6.4 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.9 ETO26142.1 - 1.5e-08 33.9 4.6 5.7e-07 28.6 0.6 2.0 1 1 1 2 2 2 2 Coatomer WD associated region DPPIV_N PF00930.16 ETO26142.1 - 2e-07 29.9 1.4 0.0018 16.9 0.1 4.2 1 1 3 5 5 5 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nup160 PF11715.3 ETO26142.1 - 3.2e-07 28.9 4.9 0.041 12.0 0.3 4.2 2 2 2 4 4 4 3 Nucleoporin Nup120/160 SGL PF08450.7 ETO26142.1 - 2.5e-06 27.0 0.7 0.094 12.0 0.1 3.6 1 1 3 4 4 4 3 SMP-30/Gluconolaconase/LRE-like region Cytochrom_D1 PF02239.11 ETO26142.1 - 2.8e-05 22.5 3.8 0.0074 14.6 0.3 3.6 1 1 3 4 4 4 1 Cytochrome D1 heme domain DUF3601 PF12208.3 ETO26142.1 - 8.1e-05 22.4 0.1 0.91 9.5 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF3601) TFIIH_BTF_p62_N PF08567.6 ETO26142.1 - 0.0036 16.9 0.1 3.7 7.2 0.0 2.9 1 1 2 3 3 3 2 TFIIH p62 subunit, N-terminal domain Nbas_N PF15492.1 ETO26142.1 - 0.0042 16.2 1.5 1.4 8.0 0.0 3.6 3 1 0 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 ETO26142.1 - 0.031 13.5 5.8 16 4.9 0.0 4.8 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Kelch_6 PF13964.1 ETO26143.1 - 9.8e-06 25.5 5.1 0.037 14.2 0.0 4.8 4 2 1 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO26143.1 - 0.0023 17.4 5.0 0.11 12.0 0.0 3.4 4 0 0 4 4 4 2 Kelch motif UPF0172 PF03665.8 ETO26143.1 - 0.017 14.5 0.5 0.4 10.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) Kelch_5 PF13854.1 ETO26143.1 - 0.022 14.6 12.4 10 6.2 0.0 5.6 6 0 0 6 6 6 0 Kelch motif Choline_transpo PF04515.7 ETO26144.1 - 8.3e-71 238.4 32.6 1.5e-70 237.5 14.9 2.4 1 1 1 2 2 2 2 Plasma-membrane choline transporter Transport_MerF PF11431.3 ETO26144.1 - 0.0029 17.2 6.7 0.081 12.5 0.4 3.7 3 0 0 3 3 3 2 Membrane transport protein MerF SPC12 PF06645.8 ETO26144.1 - 9.5 6.1 8.7 1.1 9.1 0.0 3.4 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Pkinase PF00069.20 ETO26146.1 - 1.7e-12 47.0 0.0 4e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Hid1 PF12722.2 ETO26146.1 - 1.3 6.6 14.1 0.36 8.4 5.6 2.0 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein CDC45 PF02724.9 ETO26146.1 - 6.5 4.6 14.2 0.098 10.6 1.1 2.1 2 0 0 2 2 2 0 CDC45-like protein Pkinase PF00069.20 ETO26147.1 - 9.7e-10 38.0 0.0 1.6e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain MetJ PF01340.15 ETO26147.1 - 0.032 13.9 0.0 0.075 12.7 0.0 1.6 1 0 0 1 1 1 0 Met Apo-repressor, MetJ DAG_kinase_N PF14513.1 ETO26147.1 - 0.11 12.6 0.3 0.11 12.6 0.2 2.1 3 0 0 3 3 3 0 Diacylglycerol kinase N-terminus PI3_PI4_kinase PF00454.22 ETO26148.1 - 5.9e-28 97.9 0.1 7e-27 94.4 0.1 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.1 ETO26148.1 - 0.14 11.1 0.1 0.21 10.5 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4135) VBS PF08913.5 ETO26150.1 - 0.00025 21.2 0.4 0.00092 19.4 0.3 1.9 2 0 0 2 2 2 1 Vinculin Binding Site GvpK PF05121.7 ETO26150.1 - 0.037 13.8 6.2 0.37 10.6 0.2 3.2 3 0 0 3 3 3 0 Gas vesicle protein K Cep57_MT_bd PF06657.8 ETO26150.1 - 0.36 10.8 14.5 2.1 8.3 0.2 3.5 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 PspB PF06667.7 ETO26150.1 - 0.65 9.9 3.2 2 8.4 0.2 2.7 1 1 1 2 2 2 0 Phage shock protein B DUF1192 PF06698.6 ETO26150.1 - 1 9.2 4.4 2.2 8.1 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) V_ATPase_I PF01496.14 ETO26150.1 - 8.2 4.1 10.6 11 3.7 7.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Synapsin PF02078.11 ETO26152.1 - 2e-08 34.2 0.0 3.5e-08 33.4 0.0 1.4 1 1 0 1 1 1 1 Synapsin, N-terminal domain Synapsin_C PF02750.9 ETO26152.1 - 3.1e-06 26.4 0.0 5.6e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Synapsin, ATP binding domain WD40 PF00400.27 ETO26153.1 - 1.5e-62 205.4 18.3 1.1e-12 47.3 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO26153.1 - 2.7e-07 29.1 4.8 0.061 11.4 0.1 4.1 1 1 1 3 3 3 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO26153.1 - 0.00028 20.4 0.1 0.11 11.9 0.1 2.8 1 1 0 1 1 1 1 PQQ-like domain Nucleoporin_N PF08801.6 ETO26153.1 - 0.0024 16.7 5.1 2 7.0 0.0 4.0 2 1 2 4 4 4 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO26153.1 - 0.0026 16.1 0.2 0.21 9.8 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 ETO26153.1 - 0.084 12.2 5.7 9.4 5.6 0.0 4.0 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature PD40 PF07676.7 ETO26153.1 - 1 9.1 10.2 11 5.8 0.0 5.1 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat CPSase_L_D2 PF02786.12 ETO26154.1 - 0.073 12.3 0.1 0.099 11.9 0.0 1.2 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Kelch_4 PF13418.1 ETO26155.1 - 1.9e-07 30.7 5.9 0.027 14.2 0.1 5.5 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO26155.1 - 6.9e-07 29.2 6.8 0.1 12.7 0.0 5.3 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO26155.1 - 4.7e-05 23.2 4.4 0.98 9.4 0.0 4.0 3 1 0 3 3 3 3 Kelch motif Kelch_6 PF13964.1 ETO26155.1 - 0.42 10.8 7.3 12 6.2 0.0 4.0 4 1 0 4 4 4 0 Kelch motif RhoGAP PF00620.22 ETO26156.1 - 2.5e-34 118.1 0.2 4.3e-34 117.3 0.1 1.3 1 0 0 1 1 1 1 RhoGAP domain YMF19 PF02326.10 ETO26156.1 - 0.05 14.1 2.3 0.05 14.1 1.6 2.2 3 0 0 3 3 3 0 Plant ATP synthase F0 zf-C2H2 PF00096.21 ETO26157.1 - 2.2e-08 33.9 31.8 0.00078 19.6 2.2 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETO26157.1 - 3.4e-05 23.8 27.4 0.0089 16.3 1.9 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-Di19 PF05605.7 ETO26157.1 - 0.00013 21.9 9.1 0.00013 21.9 6.3 3.3 2 1 1 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 ETO26157.1 - 0.0092 16.2 2.0 0.0092 16.2 1.4 4.9 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_2 PF12756.2 ETO26157.1 - 0.01 15.9 2.4 0.01 15.9 1.6 4.1 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.6 ETO26157.1 - 0.063 12.9 1.7 0.18 11.5 0.2 2.6 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-trcl PF13451.1 ETO26157.1 - 1.2 8.8 6.2 0.83 9.3 1.8 2.6 2 0 0 2 2 2 0 Probable zinc-binding domain WD40 PF00400.27 ETO26159.1 - 0.0046 16.8 0.3 0.014 15.2 0.1 1.9 2 0 0 2 2 2 1 WD domain, G-beta repeat Tau95 PF09734.4 ETO26161.1 - 0.024 13.9 0.9 0.033 13.5 0.6 1.2 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit DUF2353 PF09789.4 ETO26162.1 - 0.017 14.3 11.9 0.46 9.6 7.1 2.1 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) TPR_MLP1_2 PF07926.7 ETO26162.1 - 0.02 14.6 13.7 0.043 13.5 9.5 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF3086 PF11285.3 ETO26162.1 - 0.024 13.4 5.9 0.026 13.3 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) M PF02370.11 ETO26162.1 - 0.19 12.1 17.6 0.67 10.5 6.8 3.2 2 0 0 2 2 2 0 M protein repeat Noelin-1 PF12308.3 ETO26162.1 - 0.2 11.4 2.5 0.31 10.8 1.0 1.8 1 1 0 1 1 1 0 Neurogenesis glycoprotein Curto_V2 PF07325.6 ETO26162.1 - 0.47 10.1 2.2 1.7 8.2 0.2 2.1 1 1 1 2 2 2 0 Curtovirus V2 protein PEP-utilisers_N PF05524.8 ETO26162.1 - 0.51 10.1 3.0 0.68 9.7 0.2 2.1 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal RRF PF01765.14 ETO26162.1 - 0.54 9.6 7.0 0.35 10.3 3.4 1.7 1 1 1 2 2 2 0 Ribosome recycling factor TMF_DNA_bd PF12329.3 ETO26162.1 - 0.59 9.9 19.1 0.77 9.6 2.8 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Mnd1 PF03962.10 ETO26162.1 - 0.59 9.7 10.9 0.75 9.4 7.5 1.3 1 1 0 1 1 1 0 Mnd1 family Ax_dynein_light PF10211.4 ETO26162.1 - 0.79 9.5 10.6 1.6 8.5 0.5 2.2 1 1 0 2 2 2 0 Axonemal dynein light chain Spc7 PF08317.6 ETO26162.1 - 1.3 7.6 11.4 1.6 7.3 7.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DASH_Dam1 PF08653.5 ETO26162.1 - 2.4 8.0 5.4 7.4 6.4 0.5 2.6 2 1 1 3 3 3 0 DASH complex subunit Dam1 Ribosomal_L27e PF01777.13 ETO26162.1 - 2.5 8.2 8.3 5.5 7.1 2.0 2.8 1 1 1 2 2 2 0 Ribosomal L27e protein family IncA PF04156.9 ETO26162.1 - 3.5 7.1 13.4 4.1 6.9 8.7 1.5 1 1 1 2 2 2 0 IncA protein TMPIT PF07851.8 ETO26162.1 - 4 6.4 8.4 2.8 6.9 4.6 1.3 1 1 0 1 1 1 0 TMPIT-like protein Laminin_G_3 PF13385.1 ETO26163.1 - 2.4e-21 76.5 0.2 2.4e-21 76.5 0.1 2.4 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily DUF3439 PF11921.3 ETO26163.1 - 0.52 10.0 10.6 11 5.7 6.7 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) HECT PF00632.20 ETO26164.1 - 3.1e-74 249.9 0.1 7.1e-74 248.8 0.1 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 ETO26164.1 - 2.4e-11 43.8 0.4 5.1e-11 42.7 0.3 1.6 1 0 0 1 1 1 1 SPRY domain FAD-oxidase_C PF02913.14 ETO26165.1 - 7.7e-30 104.0 0.1 1.5e-29 103.0 0.0 1.5 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 ETO26165.1 - 2e-26 92.0 0.0 3.7e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Toprim_Crpt PF13342.1 ETO26165.1 - 0.018 14.6 1.0 0.058 13.0 0.7 1.9 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase Fer2 PF00111.22 ETO26166.1 - 5e-10 38.9 4.0 6.2e-10 38.6 2.8 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Pkinase PF00069.20 ETO26167.1 - 0.0028 16.8 0.2 0.0053 15.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain TFIIA PF03153.8 ETO26167.1 - 0.021 14.7 25.7 0.034 14.0 17.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.7 ETO26167.1 - 0.13 11.9 30.7 0.018 14.7 14.0 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SprA-related PF12118.3 ETO26167.1 - 0.56 9.4 19.8 0.95 8.7 13.7 1.3 1 0 0 1 1 1 0 SprA-related family Pox_Ag35 PF03286.9 ETO26167.1 - 0.88 9.0 22.2 2.6 7.5 0.6 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF77 PF01910.12 ETO26168.1 - 0.088 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF77 OB_NTP_bind PF07717.11 ETO26169.1 - 1.4e-24 86.0 0.0 2.8e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Orthopox_A5L PF06193.6 ETO26169.1 - 0.15 12.0 4.7 0.27 11.1 3.3 1.4 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like ATP-synt_E PF05680.7 ETO26169.1 - 0.77 9.7 7.0 1.4 8.9 4.9 1.5 1 0 0 1 1 1 0 ATP synthase E chain HA2 PF04408.18 ETO26170.1 - 2.7e-15 56.2 0.0 2.7e-15 56.2 0.0 2.2 2 1 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 ETO26170.1 - 1.4e-14 53.6 0.0 3.5e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETO26170.1 - 1.4e-06 27.9 0.0 3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 ETO26170.1 - 1.5e-05 25.1 0.1 4.5e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 ETO26170.1 - 0.00067 19.7 0.0 0.0033 17.4 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain T2SE PF00437.15 ETO26170.1 - 0.0014 17.6 0.0 0.0031 16.4 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.1 ETO26170.1 - 0.0026 17.6 0.0 0.03 14.2 0.0 2.5 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 ETO26170.1 - 0.0035 16.2 0.0 0.0065 15.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Sigma54_activat PF00158.21 ETO26170.1 - 0.0049 16.3 0.0 0.024 14.1 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain ResIII PF04851.10 ETO26170.1 - 0.0065 16.3 1.9 3.1 7.6 0.1 3.0 2 1 1 3 3 3 2 Type III restriction enzyme, res subunit AAA_5 PF07728.9 ETO26170.1 - 0.0074 16.0 0.2 3.9 7.2 0.0 2.7 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 ETO26170.1 - 0.009 15.7 0.0 0.027 14.2 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain SRP54 PF00448.17 ETO26170.1 - 0.016 14.6 0.0 0.049 13.0 0.0 1.8 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.1 ETO26170.1 - 0.016 15.0 0.0 0.043 13.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 ETO26170.1 - 0.018 15.5 1.4 0.42 11.1 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein PhoH PF02562.11 ETO26170.1 - 0.03 13.5 0.0 0.093 11.9 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein Flavi_DEAD PF07652.9 ETO26170.1 - 0.031 14.0 0.0 0.077 12.7 0.0 1.7 1 1 0 1 1 1 0 Flavivirus DEAD domain ABC_tran PF00005.22 ETO26170.1 - 0.035 14.3 0.0 0.035 14.3 0.0 2.7 2 1 0 2 2 2 0 ABC transporter UPF0079 PF02367.12 ETO26170.1 - 0.038 13.6 0.0 0.081 12.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 ETO26170.1 - 0.059 12.9 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 ETO26170.1 - 0.099 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Glug PF07581.7 ETO26170.1 - 0.15 12.3 0.1 0.38 11.0 0.0 1.7 1 0 0 1 1 1 0 The GLUG motif AAA_23 PF13476.1 ETO26170.1 - 0.18 12.1 0.1 0.18 12.1 0.1 2.6 1 1 1 2 2 1 0 AAA domain CAF1 PF04857.15 ETO26172.1 - 0.0025 17.2 0.0 0.0041 16.4 0.0 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease DUF4569 PF15133.1 ETO26173.1 - 0.018 14.4 9.1 0.06 12.7 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4569) TFIIF_alpha PF05793.7 ETO26173.1 - 0.073 11.4 23.4 0.071 11.4 9.6 2.3 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BLVR PF06375.6 ETO26173.1 - 0.93 9.3 22.5 0.023 14.5 2.5 3.3 4 0 0 4 4 4 0 Bovine leukaemia virus receptor (BLVR) FAM176 PF14851.1 ETO26173.1 - 4.1 7.0 10.4 1.6 8.4 1.4 2.9 3 0 0 3 3 3 0 FAM176 family ArfGap PF01412.13 ETO26174.1 - 1.4e-14 53.8 2.9 1.5e-11 44.1 0.5 2.7 2 1 0 2 2 2 2 Putative GTPase activating protein for Arf CG-1 PF03859.11 ETO26174.1 - 0.06 12.8 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 CG-1 domain Ribosomal_L21p PF00829.16 ETO26174.1 - 0.11 12.6 1.0 12 6.1 0.0 2.4 2 0 0 2 2 2 0 Ribosomal prokaryotic L21 protein zf-B_box PF00643.19 ETO26174.1 - 0.34 10.8 2.8 1.1 9.1 0.3 2.3 2 0 0 2 2 2 0 B-box zinc finger RNA_bind_2 PF10133.4 ETO26174.1 - 1.1 9.2 4.5 13 5.9 0.4 2.5 2 0 0 2 2 2 0 Predicted RNA-binding protein TF_Zn_Ribbon PF08271.7 ETO26174.1 - 1.4 8.2 5.8 56 3.1 1.8 3.4 3 1 0 3 3 3 0 TFIIB zinc-binding G-alpha PF00503.15 ETO26175.1 - 3e-19 68.9 1.4 3.2e-19 68.8 1.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit AAA_22 PF13401.1 ETO26175.1 - 0.00085 19.4 0.1 0.0017 18.4 0.0 1.5 1 1 1 2 2 2 1 AAA domain Arf PF00025.16 ETO26175.1 - 0.008 15.4 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_14 PF13173.1 ETO26175.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 ETO26175.1 - 0.011 14.8 0.3 0.082 12.1 0.0 2.1 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 ETO26175.1 - 0.028 14.4 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.9 ETO26175.1 - 0.041 13.5 0.0 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 ETO26175.1 - 0.053 14.0 0.1 0.1 13.0 0.0 1.7 2 0 0 2 2 2 0 Miro-like protein PduV-EutP PF10662.4 ETO26175.1 - 0.056 12.9 0.1 0.056 12.9 0.1 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 ETO26175.1 - 0.078 13.8 0.0 0.15 12.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain TraH_2 PF06871.6 ETO26175.1 - 0.13 11.6 0.2 3.9 6.8 0.2 2.0 2 0 0 2 2 2 0 TraH_2 DUF964 PF06133.6 ETO26175.1 - 0.15 12.0 4.8 1 9.3 1.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF964) DUF4355 PF14265.1 ETO26175.1 - 0.2 11.6 7.8 4 7.4 3.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4355) AAA_33 PF13671.1 ETO26175.1 - 0.23 11.3 1.2 0.49 10.2 0.0 2.1 2 1 0 2 2 2 0 AAA domain Daxx PF03344.10 ETO26176.1 - 0.0011 17.5 23.2 0.0015 17.1 16.1 1.1 1 0 0 1 1 1 1 Daxx Family Nop14 PF04147.7 ETO26176.1 - 0.36 8.6 23.7 0.44 8.4 16.4 1.3 1 0 0 1 1 1 0 Nop14-like family Macoilin PF09726.4 ETO26176.1 - 8.5 4.5 20.9 9.7 4.3 14.5 1.2 1 0 0 1 1 1 0 Transmembrane protein QLQ PF08880.6 ETO26177.1 - 1.2e-05 24.6 0.1 2.7e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 QLQ 60KD_IMP PF02096.15 ETO26177.1 - 1.7 8.2 5.4 0.12 12.0 0.3 1.7 2 0 0 2 2 2 0 60Kd inner membrane protein OST-HTH PF12872.2 ETO26180.1 - 0.039 13.7 0.2 0.091 12.6 0.0 1.6 2 0 0 2 2 2 0 OST-HTH/LOTUS domain Apc9 PF12856.2 ETO26180.1 - 0.074 13.1 0.7 0.14 12.2 0.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 9 DUF2895 PF11444.3 ETO26181.1 - 0.013 14.7 1.7 0.013 14.7 1.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2895) Chordopox_A33R PF05966.7 ETO26181.1 - 0.29 9.9 7.6 0.69 8.6 5.3 1.7 1 0 0 1 1 1 0 Chordopoxvirus A33R protein PRA1 PF03208.14 ETO26181.1 - 0.56 9.5 4.5 0.86 8.9 3.1 1.2 1 0 0 1 1 1 0 PRA1 family protein TRP PF06011.7 ETO26181.1 - 1.1 7.7 10.3 0.025 13.1 1.6 2.1 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel Ribosomal_L4 PF00573.17 ETO26183.1 - 2.2e-27 95.6 0.2 4.7e-27 94.6 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 ETO26183.1 - 8e-16 57.7 0.9 8e-16 57.7 0.6 2.1 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain DUF104 PF01954.11 ETO26183.1 - 0.072 13.1 3.6 0.1 12.6 0.1 2.9 4 0 0 4 4 4 0 Protein of unknown function DUF104 p450 PF00067.17 ETO26184.1 - 6.9e-39 133.6 0.5 1.3e-37 129.4 0.0 2.5 2 1 0 2 2 2 1 Cytochrome P450 DUF3779 PF12621.3 ETO26184.1 - 0.09 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Phosphate metabolism protein IpaB_EvcA PF03278.8 ETO26184.1 - 0.15 11.2 0.4 14 4.8 0.0 2.3 2 0 0 2 2 2 0 IpaB/EvcA family RNase_PH PF01138.16 ETO26185.1 - 5.3e-08 33.2 0.0 9.9e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 ETO26185.1 - 1.6e-05 24.7 0.2 3.1e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 KH_1 PF00013.24 ETO26185.1 - 0.01 15.4 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 0 KH domain KH_3 PF13014.1 ETO26185.1 - 0.073 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 KH domain FYVE PF01363.16 ETO26187.1 - 1.2e-09 37.9 9.1 3.1e-09 36.5 6.3 1.8 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 ETO26187.1 - 0.07 13.0 6.3 0.36 10.7 4.4 2.2 1 0 0 1 1 1 0 FYVE-type zinc finger LcrG PF07216.7 ETO26189.1 - 0.086 12.8 0.3 0.19 11.7 0.2 1.6 1 0 0 1 1 1 0 LcrG protein ILVD_EDD PF00920.16 ETO26189.1 - 0.14 10.5 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 Dehydratase family C2 PF00168.25 ETO26191.1 - 1e-17 63.7 0.5 2.2e-17 62.6 0.2 1.7 2 0 0 2 2 2 1 C2 domain HALZ PF02183.13 ETO26191.1 - 0.0035 17.0 0.1 0.007 16.0 0.1 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper SlyX PF04102.7 ETO26191.1 - 2.2 8.6 8.4 0.24 11.8 2.8 1.7 2 0 0 2 2 2 0 SlyX COG5 PF10392.4 ETO26194.1 - 2.4 8.1 11.1 0.12 12.3 1.5 2.5 2 1 0 2 2 2 0 Golgi transport complex subunit 5 TPR_11 PF13414.1 ETO26195.1 - 8.2e-06 25.3 0.2 1.9e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 TPR repeat TPR_8 PF13181.1 ETO26195.1 - 1.8e-05 24.1 1.3 3.7e-05 23.2 0.3 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO26195.1 - 0.002 18.0 0.0 0.005 16.7 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO26195.1 - 0.011 15.2 2.0 0.02 14.4 0.4 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Foie-gras_1 PF11817.3 ETO26195.1 - 0.016 14.7 0.1 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Foie gras liver health family 1 TPR_2 PF07719.12 ETO26195.1 - 0.092 12.7 2.2 0.15 12.0 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat HELP PF03451.9 ETO26196.1 - 0.1 12.1 0.1 0.2 11.1 0.1 1.5 1 1 0 1 1 1 0 HELP motif Med15_fungi PF05397.7 ETO26197.1 - 0.051 13.5 0.7 0.12 12.3 0.5 1.6 1 0 0 1 1 1 0 Mediator complex subunit 15 PT PF04886.7 ETO26198.1 - 0.0024 17.1 1.9 0.0035 16.6 1.3 1.2 1 0 0 1 1 1 1 PT repeat 2-Hacid_dh_C PF02826.14 ETO26198.1 - 0.0024 17.0 0.0 0.0036 16.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2569 PF10754.4 ETO26198.1 - 0.012 15.7 0.3 0.012 15.7 0.2 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2569) DUF1829 PF08862.5 ETO26198.1 - 1.2 9.5 4.8 0.34 11.2 0.2 2.3 3 1 0 3 3 3 0 Domain of unknown function DUF1829 CbiK PF06180.6 ETO26200.1 - 0.019 14.0 0.1 2 7.4 0.0 2.2 2 0 0 2 2 2 0 Cobalt chelatase (CbiK) DUF2555 PF10742.4 ETO26200.1 - 0.041 13.5 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2555) WD40 PF00400.27 ETO26201.1 - 1.3e-19 69.2 10.1 3e-06 26.9 0.5 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat PQQ PF01011.16 ETO26201.1 - 0.00036 19.9 0.8 0.004 16.6 0.0 3.0 3 0 0 3 3 3 1 PQQ enzyme repeat DUF706 PF05153.10 ETO26203.1 - 5e-104 347.0 9.9 5e-104 347.0 6.9 1.5 2 0 0 2 2 2 1 Family of unknown function (DUF706) Suf PF05843.9 ETO26203.1 - 0.029 14.0 0.3 0.047 13.4 0.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAP_assoc PF03828.14 ETO26204.1 - 0.0002 21.2 0.1 0.00063 19.6 0.1 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 ETO26204.1 - 0.013 15.8 0.0 0.038 14.3 0.0 1.8 1 0 0 1 1 1 0 Nucleotidyltransferase domain Sigma70_ner PF04546.8 ETO26205.1 - 0.036 13.6 2.5 0.1 12.2 0.6 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region RICTOR_phospho PF14665.1 ETO26205.1 - 0.058 13.4 1.0 0.16 12.1 0.2 2.0 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site FAM176 PF14851.1 ETO26205.1 - 0.22 11.1 2.8 9.6 5.8 1.3 2.2 2 0 0 2 2 2 0 FAM176 family Zip PF02535.17 ETO26206.1 - 1.5e-05 24.2 3.0 1.5e-05 24.2 2.1 2.3 1 1 1 2 2 2 1 ZIP Zinc transporter YajC PF02699.10 ETO26209.1 - 0.048 13.3 0.1 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit DUF2214 PF09980.4 ETO26209.1 - 0.16 11.6 0.5 0.33 10.6 0.1 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2214) Abhydrolase_5 PF12695.2 ETO26210.1 - 1.4e-14 54.1 0.0 3.6e-14 52.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETO26210.1 - 4.8e-09 36.4 0.0 1.5e-08 34.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETO26210.1 - 5.2e-06 26.1 0.0 1.9e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 ETO26210.1 - 2.5e-05 23.9 0.0 5.4e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 ETO26210.1 - 0.00051 19.5 0.5 0.0027 17.1 0.0 2.3 1 1 1 2 2 2 1 Putative esterase Peptidase_S9 PF00326.16 ETO26210.1 - 0.0034 16.6 0.0 0.26 10.4 0.0 2.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 ETO26210.1 - 0.035 13.5 0.4 7.5 5.9 0.0 2.7 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Esterase_phd PF10503.4 ETO26210.1 - 0.065 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase Zip PF02535.17 ETO26210.1 - 1.6 7.6 6.0 3.6 6.5 4.2 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4239 PF14023.1 ETO26211.1 - 0.011 15.1 0.0 0.025 13.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) EVI2A PF05399.6 ETO26212.1 - 0.0031 16.7 0.1 0.0063 15.7 0.1 1.4 1 0 0 1 1 1 1 Ectropic viral integration site 2A protein (EVI2A) Pkinase PF00069.20 ETO26213.1 - 2.7e-09 36.5 0.0 3.8e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF148 PF02520.12 ETO26214.1 - 0.012 15.4 2.0 0.056 13.2 1.3 1.9 1 1 1 2 2 2 0 Domain of unknown function DUF148 UvsW PF11637.3 ETO26214.1 - 0.013 15.1 0.8 0.038 13.6 0.6 1.7 1 0 0 1 1 1 0 ATP-dependant DNA helicase UvsW AAA_13 PF13166.1 ETO26214.1 - 0.032 12.7 2.5 0.036 12.5 1.7 1.0 1 0 0 1 1 1 0 AAA domain SPX PF03105.14 ETO26214.1 - 0.056 13.2 0.7 0.063 13.0 0.5 1.1 1 0 0 1 1 1 0 SPX domain Baculo_PEP_C PF04513.7 ETO26214.1 - 0.085 12.6 2.9 0.17 11.6 2.0 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3800 PF12686.2 ETO26214.1 - 0.1 12.2 0.4 0.12 12.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3800) Reo_sigmaC PF04582.7 ETO26217.1 - 0.025 13.7 0.5 0.025 13.7 0.4 4.2 4 1 1 5 5 5 0 Reovirus sigma C capsid protein Ada3 PF10198.4 ETO26218.1 - 4.8 6.9 10.8 11 5.7 2.2 3.3 2 1 1 3 3 3 0 Histone acetyltransferases subunit 3 NIF PF03031.13 ETO26221.1 - 8.4e-20 71.0 0.1 2.2e-19 69.6 0.1 1.7 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF908 PF06012.7 ETO26221.1 - 0.073 12.3 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Zip PF02535.17 ETO26221.1 - 0.44 9.5 3.3 0.59 9.0 2.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3439 PF11921.3 ETO26221.1 - 0.52 10.0 3.4 0.58 9.9 1.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Kinesin PF00225.18 ETO26222.1 - 1.2e-31 109.7 0.6 2e-31 108.9 0.4 1.3 1 0 0 1 1 1 1 Kinesin motor domain Kinesin PF00225.18 ETO26223.1 - 5.7e-48 163.3 1.4 5.7e-48 163.3 1.0 2.2 2 0 0 2 2 2 1 Kinesin motor domain Methyltransf_12 PF08242.7 ETO26223.1 - 0.12 12.8 1.6 0.43 11.0 1.1 1.9 1 0 0 1 1 1 0 Methyltransferase domain PI3_PI4_kinase PF00454.22 ETO26224.1 - 4.8e-23 81.8 0.6 1.8e-12 47.2 0.1 2.6 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase SOBP PF15279.1 ETO26225.1 - 0.28 11.5 4.1 0.39 11.0 2.8 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein GEMIN8 PF15348.1 ETO26225.1 - 0.28 11.2 3.9 0.3 11.1 1.9 1.5 1 1 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Nnf1 PF03980.9 ETO26226.1 - 0.038 13.9 1.6 0.07 13.1 0.3 2.0 2 0 0 2 2 2 0 Nnf1 Nup88 PF10168.4 ETO26226.1 - 0.095 10.5 2.2 0.1 10.4 1.6 1.0 1 0 0 1 1 1 0 Nuclear pore component Proteasome PF00227.21 ETO26227.1 - 4.3e-18 65.2 2.0 1.5e-17 63.5 1.4 1.7 1 1 0 1 1 1 1 Proteasome subunit PUA PF01472.15 ETO26227.1 - 0.056 13.1 0.3 0.14 11.8 0.2 1.6 1 0 0 1 1 1 0 PUA domain LRRC37AB_C PF14914.1 ETO26227.1 - 0.061 12.7 0.1 0.65 9.4 0.0 2.1 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain TMEM154 PF15102.1 ETO26229.1 - 0.044 13.4 3.3 0.12 12.0 2.3 1.7 1 0 0 1 1 1 0 TMEM154 protein family Death_2 PF14786.1 ETO26229.1 - 0.15 11.7 1.4 0.47 10.1 0.1 2.3 2 0 0 2 2 2 0 Tube Death domain SSP160 PF06933.6 ETO26229.1 - 3.5 5.4 16.1 7.5 4.4 11.1 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TPR_12 PF13424.1 ETO26230.1 - 4.8e-24 84.0 6.2 5.9e-13 48.5 0.1 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO26230.1 - 8.8e-19 66.9 15.9 2.9e-13 49.2 4.7 2.1 1 1 1 2 2 2 2 TPR repeat TPR_7 PF13176.1 ETO26230.1 - 1.8e-12 46.0 1.0 0.0003 20.3 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO26230.1 - 5.4e-12 44.5 15.3 2.6e-06 26.8 0.7 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO26230.1 - 1.6e-10 40.0 12.9 0.00013 21.5 0.4 3.6 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO26230.1 - 5e-10 38.5 18.2 2.3e-06 26.9 0.7 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO26230.1 - 5.3e-09 35.7 0.0 0.0025 17.6 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO26230.1 - 1.7e-05 24.9 0.3 2.2 8.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO26230.1 - 0.0015 18.6 4.9 0.25 11.6 0.5 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO26230.1 - 0.0018 18.9 0.1 0.093 13.4 0.1 2.5 2 1 1 3 3 3 2 Tetratricopeptide repeat SNAP PF14938.1 ETO26230.1 - 0.0024 17.0 3.0 0.048 12.8 0.7 2.2 1 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP MIT PF04212.13 ETO26230.1 - 0.0025 17.6 1.9 0.4 10.5 0.1 2.6 2 1 1 3 3 3 1 MIT (microtubule interacting and transport) domain Sec5 PF15469.1 ETO26230.1 - 0.013 15.2 0.3 0.02 14.6 0.2 1.3 1 1 0 1 1 1 0 Exocyst complex component Sec5 DUF2225 PF09986.4 ETO26230.1 - 0.031 13.7 5.1 0.44 9.9 1.5 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_19 PF14559.1 ETO26230.1 - 0.041 14.2 0.0 0.12 12.7 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.2 ETO26230.1 - 0.088 12.6 0.1 0.36 10.6 0.1 1.9 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) TPR_3 PF07720.7 ETO26230.1 - 7.6 6.4 10.1 0.74 9.6 0.7 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Rab3-GTPase_cat PF13890.1 ETO26231.1 - 0.022 14.1 0.2 0.034 13.5 0.1 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit Fer4_12 PF13353.1 ETO26231.1 - 0.023 14.7 0.8 4.4 7.4 0.0 3.0 1 1 2 3 3 3 0 4Fe-4S single cluster domain DUF4164 PF13747.1 ETO26231.1 - 0.078 13.1 0.2 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Spore_coat_CotO PF14153.1 ETO26232.1 - 2.2 7.6 8.7 3.7 6.9 6.0 1.3 1 0 0 1 1 1 0 Spore coat protein CotO CAP_GLY PF01302.20 ETO26235.1 - 3.8e-10 39.3 0.7 7e-10 38.4 0.1 1.7 2 0 0 2 2 2 1 CAP-Gly domain WGR PF05406.10 ETO26237.1 - 0.00082 19.2 0.1 0.0019 18.0 0.1 1.6 1 0 0 1 1 1 1 WGR domain DUF2201_N PF13203.1 ETO26237.1 - 0.45 9.6 12.4 0.57 9.3 8.6 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain EXS PF03124.9 ETO26238.1 - 5.4e-07 28.9 0.6 7e-07 28.5 0.4 1.2 1 0 0 1 1 1 1 EXS family EXS PF03124.9 ETO26239.1 - 3.4e-24 85.5 11.4 5.5e-24 84.8 7.9 1.3 1 0 0 1 1 1 1 EXS family SPX PF03105.14 ETO26239.1 - 5.4e-08 32.9 0.3 7.7e-08 32.4 0.2 1.2 1 0 0 1 1 1 1 SPX domain DUF2360 PF10152.4 ETO26239.1 - 0.18 12.0 3.5 0.29 11.4 2.4 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Mucin PF01456.12 ETO26239.1 - 1.1 9.0 9.5 1.8 8.3 6.6 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Chorein_N PF12624.2 ETO26241.1 - 0.00028 20.4 2.3 0.00029 20.3 0.1 2.1 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter PH PF00169.24 ETO26242.1 - 9.6e-14 51.4 1.7 9.6e-14 51.4 1.2 2.2 2 0 0 2 2 2 1 PH domain PH_3 PF14593.1 ETO26242.1 - 2e-06 27.5 4.1 6.4e-06 25.9 0.2 2.8 3 0 0 3 3 3 1 PH domain PH_11 PF15413.1 ETO26242.1 - 7.1e-06 26.2 4.6 0.0001 22.4 3.2 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 ETO26242.1 - 0.00047 20.1 0.6 0.001 19.0 0.4 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain HSP90 PF00183.13 ETO26243.1 - 9.3e-13 47.4 0.0 1.2e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Hsp90 protein WWE PF02825.15 ETO26245.1 - 3.3e-08 32.8 0.7 5.2e-08 32.2 0.5 1.3 1 0 0 1 1 1 1 WWE domain DZR PF12773.2 ETO26245.1 - 2e-05 24.3 0.5 3.1e-05 23.7 0.4 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-DHHC PF01529.15 ETO26245.1 - 0.078 12.3 0.3 0.12 11.7 0.2 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase zf-ribbon_3 PF13248.1 ETO26245.1 - 0.12 11.5 2.7 0.18 11.0 1.9 1.3 1 0 0 1 1 1 0 zinc-ribbon domain DUF2291 PF10054.4 ETO26245.1 - 0.14 11.4 0.3 7.3 5.8 0.0 2.2 1 1 1 2 2 2 0 Predicted periplasmic lipoprotein (DUF2291) zinc_ribbon_2 PF13240.1 ETO26245.1 - 7.6 6.1 8.7 14 5.2 6.0 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Succ_DH_flav_C PF02910.15 ETO26246.1 - 0.043 13.6 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 Fumarate reductase flavoprotein C-term Mog1 PF04603.7 ETO26247.1 - 4.8e-24 84.8 0.2 6e-22 78.1 0.1 2.2 2 0 0 2 2 2 2 Ran-interacting Mog1 protein F-box-like PF12937.2 ETO26248.1 - 0.011 15.3 0.7 0.028 14.1 0.5 1.7 1 0 0 1 1 1 0 F-box-like Mucin PF01456.12 ETO26248.1 - 0.05 13.3 7.2 0.091 12.5 5.0 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Mem_trans PF03547.13 ETO26249.1 - 0.017 13.4 3.9 0.027 12.7 2.7 1.4 1 1 0 1 1 1 0 Membrane transport protein Pox_Ag35 PF03286.9 ETO26249.1 - 0.045 13.2 19.6 0.1 12.1 13.6 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Sporozoite_P67 PF05642.6 ETO26249.1 - 0.46 8.2 14.3 0.69 7.7 9.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mitofilin PF09731.4 ETO26249.1 - 0.48 9.0 27.5 0.71 8.4 19.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Zip PF02535.17 ETO26249.1 - 0.89 8.4 4.6 1.6 7.6 2.1 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter AP-5_subunit_s1 PF15001.1 ETO26249.1 - 0.91 9.4 9.7 1.2 9.0 6.3 1.5 1 1 0 1 1 1 0 AP-5 complex subunit sigma-1 Ndc1_Nup PF09531.5 ETO26249.1 - 4.4 5.6 13.8 7 4.9 9.6 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2201_N PF13203.1 ETO26249.1 - 4.9 6.2 11.8 8.3 5.4 8.1 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain RNA_pol_Rpb1_5 PF04998.12 ETO26249.1 - 4.9 6.3 11.2 8.3 5.5 7.8 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Peptidase_S64 PF08192.6 ETO26249.1 - 6.2 5.0 21.3 8.9 4.5 14.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 zf-CCCH PF00642.19 ETO26250.1 - 2e-06 27.3 5.9 2e-06 27.3 4.1 3.3 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 ETO26250.1 - 0.03 14.3 11.7 0.11 12.5 3.0 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Macoilin PF09726.4 ETO26250.1 - 0.18 10.0 18.7 0.23 9.6 13.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Bap31 PF05529.7 ETO26254.1 - 0.057 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like TPR_12 PF13424.1 ETO26255.1 - 2.6e-32 110.5 3.7 1.7e-14 53.5 1.6 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO26255.1 - 1.5e-18 66.0 0.4 4.3e-06 26.4 0.5 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO26255.1 - 4.7e-17 60.3 4.3 5e-05 22.7 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO26255.1 - 9.1e-17 59.8 13.8 1e-05 24.8 0.1 4.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO26255.1 - 2.3e-16 59.1 5.5 2.3e-12 46.3 0.5 3.1 3 1 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 ETO26255.1 - 3.9e-15 54.4 8.4 0.00083 19.0 0.5 4.7 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO26255.1 - 4.7e-14 51.0 6.5 0.0019 17.8 0.1 4.9 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO26255.1 - 8.6e-09 35.2 0.1 0.41 11.4 0.2 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO26255.1 - 5.7e-07 29.5 3.8 0.036 14.5 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO26255.1 - 6.7e-06 26.6 0.2 0.012 16.3 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO26255.1 - 0.0001 22.2 2.0 0.43 10.9 0.0 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO26255.1 - 0.00015 21.8 4.7 0.00019 21.5 1.1 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 ETO26255.1 - 0.004 16.3 2.0 0.1 11.8 0.0 3.7 4 1 0 4 4 4 1 SHNi-TPR SNAP PF14938.1 ETO26255.1 - 0.0053 15.9 3.9 0.43 9.6 0.2 2.3 1 1 1 3 3 2 2 Soluble NSF attachment protein, SNAP TPR_4 PF07721.9 ETO26255.1 - 0.035 14.5 0.1 0.12 12.8 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETO26255.1 - 0.053 13.8 2.3 0.96 9.8 0.3 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat Nanovirus_coat PF04660.7 ETO26255.1 - 0.066 12.9 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Nanovirus coat protein TPR_3 PF07720.7 ETO26255.1 - 0.09 12.5 5.9 2.9 7.7 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1149 PF06619.6 ETO26255.1 - 0.099 12.5 0.7 0.25 11.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1149) MIT PF04212.13 ETO26255.1 - 0.97 9.3 0.0 0.97 9.3 0.0 3.8 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain Kelch_1 PF01344.20 ETO26256.1 - 8.6e-08 31.6 5.6 0.0013 18.2 0.1 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO26256.1 - 1e-05 25.4 2.3 0.081 13.1 0.1 3.7 3 1 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 ETO26256.1 - 0.00069 19.7 1.2 0.12 12.5 0.0 4.1 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO26256.1 - 0.0042 17.0 1.3 5.6 7.0 0.1 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 ETO26256.1 - 0.038 13.7 1.6 5.8 6.8 0.0 3.3 3 0 0 3 3 3 0 Kelch motif Rhodanese PF00581.15 ETO26257.1 - 2.6e-14 53.5 0.0 2.4e-08 34.3 0.0 3.0 2 1 0 2 2 2 2 Rhodanese-like domain BPD_transp_2 PF02653.11 ETO26257.1 - 0.1 11.5 0.0 0.43 9.4 0.0 1.8 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component SpoVAD PF07451.6 ETO26258.1 - 0.15 10.4 0.4 0.23 9.8 0.3 1.2 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) BTB PF00651.26 ETO26260.1 - 0.0027 17.6 1.1 0.0051 16.7 0.1 2.0 2 0 0 2 2 2 1 BTB/POZ domain TBPIP_N PF15517.1 ETO26260.1 - 0.59 9.8 6.7 2.1 8.0 0.1 3.1 3 0 0 3 3 3 0 TBP-interacting protein N-terminus GOLD_2 PF13897.1 ETO26260.1 - 0.85 9.8 7.4 3.9 7.6 0.3 2.5 2 1 0 2 2 2 0 Golgi-dynamics membrane-trafficking Pinin_SDK_memA PF04696.8 ETO26260.1 - 8 6.0 14.1 0.046 13.3 1.0 2.6 2 1 0 2 2 2 0 pinin/SDK/memA/ protein conserved region H_PPase PF03030.11 ETO26261.1 - 0.23 9.6 1.5 0.29 9.3 1.0 1.1 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase DUF727 PF05303.7 ETO26262.1 - 0.047 13.4 0.5 0.064 13.0 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF727) DUF2457 PF10446.4 ETO26263.1 - 0.0029 16.3 17.4 0.0029 16.3 12.0 3.5 3 2 0 3 3 3 2 Protein of unknown function (DUF2457) Macoilin PF09726.4 ETO26264.1 - 1 7.5 7.9 1.1 7.4 5.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Miff PF05644.6 ETO26264.1 - 2 7.9 6.3 2.8 7.5 4.4 1.2 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff DUF2967 PF11179.3 ETO26264.1 - 3.2 7.1 10.0 6.6 6.1 6.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2967) CobT PF06213.7 ETO26265.1 - 0.62 9.1 10.7 1.2 8.1 7.4 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PrsW-protease PF13367.1 ETO26266.1 - 1.7e-12 46.8 10.3 1.7e-12 46.8 7.1 2.3 2 1 0 2 2 2 1 Protease prsW family DUF2324 PF10086.4 ETO26266.1 - 0.00043 19.5 4.0 0.0011 18.2 1.2 2.7 3 0 0 3 3 3 1 Putative membrane peptidase family (DUF2324) UDPG_MGDP_dh_N PF03721.9 ETO26267.1 - 0.035 13.4 0.5 0.067 12.5 0.1 1.6 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CDC45 PF02724.9 ETO26268.1 - 5.5 4.8 8.5 7.3 4.4 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein CitMHS PF03600.11 ETO26270.1 - 0.0098 14.5 3.9 0.83 8.1 4.0 2.7 3 1 0 3 3 3 2 Citrate transporter Pkinase_Tyr PF07714.12 ETO26271.1 - 4.4e-42 143.9 0.0 6.3e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 ETO26271.1 - 3.4e-26 91.9 0.0 6.2e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain NOA36 PF06524.7 ETO26271.1 - 1.2 8.3 5.2 2 7.6 3.6 1.3 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.4 ETO26272.1 - 0.31 9.7 4.6 0.41 9.3 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RFX1_trans_act PF04589.8 ETO26273.1 - 0.13 12.0 3.4 0.25 11.0 2.3 1.5 1 0 0 1 1 1 0 RFX1 transcription activation region Med15 PF09606.5 ETO26273.1 - 0.26 9.4 21.8 0.33 9.0 15.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TEX19 PF15553.1 ETO26273.1 - 0.36 10.6 3.2 0.52 10.1 2.2 1.4 1 0 0 1 1 1 0 Testis-expressed protein 19 DUF2296 PF10058.4 ETO26274.1 - 0.075 12.7 1.9 0.2 11.4 1.3 1.7 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) SET PF00856.23 ETO26275.1 - 3.7e-05 24.0 5.1 0.00039 20.7 0.4 2.6 2 1 0 2 2 2 2 SET domain Sld5 PF05916.6 ETO26275.1 - 0.096 12.9 7.2 1.1 9.5 0.8 2.9 2 1 1 3 3 3 0 GINS complex protein Adaptin_binding PF10199.4 ETO26275.1 - 2.9 8.1 20.4 0.94 9.7 7.9 2.3 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Arf PF00025.16 ETO26276.1 - 3.3e-45 153.4 4.9 3.3e-29 101.3 0.3 4.1 2 1 0 3 3 3 3 ADP-ribosylation factor family SRPRB PF09439.5 ETO26276.1 - 1.3e-05 24.4 0.1 0.001 18.3 0.1 3.0 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 ETO26276.1 - 2.2e-05 23.3 0.2 0.002 16.8 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit Ras PF00071.17 ETO26276.1 - 0.00058 19.2 0.1 0.016 14.6 0.0 3.0 2 1 1 3 3 3 1 Ras family Gtr1_RagA PF04670.7 ETO26276.1 - 0.0044 16.1 0.5 1.5 7.9 0.0 2.9 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region zf-C3HC4_3 PF13920.1 ETO26277.1 - 2.7e-13 49.3 9.4 4.8e-13 48.5 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO26277.1 - 9.6e-06 25.5 12.5 1.9e-05 24.5 8.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 ETO26277.1 - 1.1e-05 24.8 4.5 3.2e-05 23.3 3.1 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.1 ETO26277.1 - 2.3e-05 24.0 10.2 4.9e-05 22.9 7.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 ETO26277.1 - 0.0011 18.5 13.5 0.0031 17.1 9.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO26277.1 - 0.0011 18.7 11.2 0.0025 17.6 7.7 1.6 1 0 0 1 1 1 1 Ring finger domain Cluap1 PF10234.4 ETO26277.1 - 0.22 10.7 7.4 1.1 8.3 0.1 2.3 2 0 0 2 2 2 0 Clusterin-associated protein-1 ACCA PF03255.9 ETO26277.1 - 0.25 10.8 4.4 0.8 9.2 0.1 2.3 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit HSCB_C PF07743.8 ETO26277.1 - 0.51 10.8 9.2 2.8 8.4 0.6 2.8 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain DUF4140 PF13600.1 ETO26277.1 - 0.58 10.6 5.8 2.9 8.3 0.1 2.7 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) ABC_tran_2 PF12848.2 ETO26277.1 - 0.58 10.0 12.4 0.24 11.2 3.2 2.5 2 0 0 2 2 2 0 ABC transporter DUF607 PF04678.8 ETO26277.1 - 1.3 8.8 6.5 0.52 10.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF607 MerR-DNA-bind PF09278.6 ETO26277.1 - 2.3 8.6 7.0 0.71 10.3 0.4 2.9 3 0 0 3 3 3 0 MerR, DNA binding Siah-Interact_N PF09032.6 ETO26277.1 - 5.7 7.0 11.6 22 5.2 0.3 2.7 2 0 0 2 2 2 0 Siah interacting protein, N terminal VIT1 PF01988.14 ETO26277.1 - 9.4 5.6 7.6 2.2 7.6 1.0 2.1 2 0 0 2 2 2 0 VIT family DUF4220 PF13968.1 ETO26279.1 - 0.016 14.3 2.3 0.035 13.1 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Mem_trans PF03547.13 ETO26279.1 - 0.039 12.2 3.7 0.043 12.1 2.6 1.3 1 0 0 1 1 1 0 Membrane transport protein Menin PF05053.8 ETO26279.1 - 0.94 7.5 16.3 1.7 6.6 11.3 1.4 1 0 0 1 1 1 0 Menin DUF1510 PF07423.6 ETO26279.1 - 8.7 5.6 35.3 1.2 8.4 20.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) WW PF00397.21 ETO26280.1 - 0.14 12.0 0.8 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 WW domain DUF2457 PF10446.4 ETO26280.1 - 0.4 9.3 8.7 0.6 8.7 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF2408 PF10303.4 ETO26280.1 - 0.44 10.6 8.8 2.5 8.2 3.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) DUF4564 PF15169.1 ETO26280.1 - 1 9.0 6.8 0.66 9.6 1.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4564) DUF2535 PF10751.4 ETO26285.1 - 0.12 12.5 0.1 0.16 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2535) dCMP_cyt_deam_1 PF00383.17 ETO26286.1 - 4.5e-21 74.3 6.3 6.9e-21 73.8 4.4 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 ETO26286.1 - 0.065 12.8 3.8 0.12 11.9 2.7 1.4 1 1 0 1 1 1 0 APOBEC-like N-terminal domain Bd3614-deam PF14439.1 ETO26286.1 - 0.12 12.2 3.4 0.26 11.1 2.3 1.6 1 1 0 1 1 1 0 Bd3614-like deaminase DUF3795 PF12675.2 ETO26286.1 - 0.73 10.0 6.4 1.4 9.1 4.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) Tektin PF03148.9 ETO26288.1 - 0.013 14.0 0.3 0.016 13.7 0.2 1.2 1 0 0 1 1 1 0 Tektin family V-SNARE PF05008.10 ETO26288.1 - 0.046 13.8 3.2 0.094 12.8 2.2 1.6 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus HR1 PF02185.11 ETO26288.1 - 0.46 10.2 5.8 0.1 12.3 1.0 2.0 2 1 1 3 3 3 0 Hr1 repeat V-SNARE_C PF12352.3 ETO26289.1 - 1.2e-11 44.4 16.1 5.1e-06 26.4 3.2 2.8 3 0 0 3 3 2 2 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 ETO26289.1 - 5e-11 42.1 9.0 2.6e-05 23.8 0.4 3.2 3 0 0 3 3 3 2 Sec20 Use1 PF09753.4 ETO26289.1 - 0.0002 20.9 15.8 0.0019 17.6 4.8 2.5 2 1 0 2 2 2 2 Membrane fusion protein Use1 SNARE PF05739.14 ETO26289.1 - 0.0012 18.4 2.2 0.0012 18.4 1.5 3.8 4 0 0 4 4 4 1 SNARE domain DUF607 PF04678.8 ETO26289.1 - 0.019 14.9 6.6 4.5 7.1 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function, DUF607 Herpes_US9 PF06072.6 ETO26289.1 - 0.027 14.2 0.8 0.027 14.2 0.6 3.3 3 1 1 4 4 3 0 Alphaherpesvirus tegument protein US9 GCOM2 PF15328.1 ETO26289.1 - 0.085 12.5 8.4 0.015 15.0 2.4 1.9 2 0 0 2 2 2 0 Putative GRINL1B complex locus protein 2 NPV_P10 PF05531.7 ETO26289.1 - 0.18 12.0 11.3 4.9 7.4 0.6 3.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.7 ETO26289.1 - 0.26 11.0 11.6 1.2 8.9 0.3 3.3 3 0 0 3 3 3 0 Laminin Domain II NnrS PF05940.7 ETO26289.1 - 0.26 10.1 8.5 0.036 12.9 2.9 1.6 2 0 0 2 2 2 0 NnrS protein Methyltransf_4 PF02390.12 ETO26289.1 - 0.37 9.8 5.6 1.2 8.1 0.1 2.7 2 1 0 2 2 2 0 Putative methyltransferase DUF883 PF05957.8 ETO26289.1 - 0.41 11.0 6.3 3.6 8.0 0.1 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Viral_Beta_CD PF04530.7 ETO26289.1 - 0.7 10.0 9.4 15 5.7 0.0 3.6 2 1 1 3 3 3 0 Viral Beta C/D like family V-SNARE PF05008.10 ETO26289.1 - 0.88 9.7 9.1 0.62 10.2 0.3 3.4 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF3394 PF11874.3 ETO26289.1 - 1.4 8.3 6.2 8.6 5.8 1.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3394) Synaptobrevin PF00957.16 ETO26289.1 - 2.5 7.7 22.0 1.9 8.1 1.8 4.0 3 1 0 3 3 3 0 Synaptobrevin Uds1 PF15456.1 ETO26289.1 - 5.3 7.0 10.6 4.7 7.2 0.4 2.7 3 0 0 3 3 3 0 Up-regulated During Septation DUF2407 PF10302.4 ETO26291.1 - 0.02 15.0 0.0 0.089 12.9 0.0 2.0 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain ATP-grasp PF02222.17 ETO26291.1 - 0.051 12.9 0.1 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain AgrB PF04647.10 ETO26291.1 - 0.14 11.1 2.4 0.33 10.0 0.1 2.0 2 0 0 2 2 2 0 Accessory gene regulator B TFIIF_beta PF02270.10 ETO26291.1 - 0.34 10.6 4.4 0.7 9.6 2.9 1.5 1 1 1 2 2 2 0 Transcription initiation factor IIF, beta subunit Bac_luciferase PF00296.15 ETO26292.1 - 0.11 11.6 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Luciferase-like monooxygenase POX PF07526.6 ETO26293.1 - 0.088 13.0 0.5 0.19 11.9 0.4 1.6 1 0 0 1 1 1 0 Associated with HOX RRM_1 PF00076.17 ETO26294.1 - 2.3e-23 81.5 0.0 2.9e-14 52.4 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO26294.1 - 8.1e-14 51.3 0.1 4.7e-09 36.0 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO26294.1 - 1.1e-13 50.8 2.4 5.8e-07 29.2 0.0 3.6 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 ETO26294.1 - 0.0015 18.3 37.5 0.0026 17.5 22.6 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) DUF3737 PF12541.3 ETO26294.1 - 0.0036 16.3 0.2 0.0051 15.8 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3737) PRP38_assoc PF12871.2 ETO26294.1 - 0.017 15.6 37.1 0.017 15.6 25.7 2.4 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF4051 PF13260.1 ETO26294.1 - 0.08 12.2 0.0 0.28 10.5 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) MIP-T3 PF10243.4 ETO26294.1 - 0.081 11.3 12.7 0.086 11.3 5.0 2.0 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 BRF1 PF07741.8 ETO26294.1 - 0.14 12.3 9.3 0.2 11.9 0.5 3.0 2 1 0 2 2 2 0 Brf1-like TBP-binding domain FAM176 PF14851.1 ETO26294.1 - 0.15 11.7 6.0 0.97 9.0 0.0 2.2 2 0 0 2 2 2 0 FAM176 family Atrophin-1 PF03154.10 ETO26294.1 - 2.1 6.3 20.0 0.044 11.9 8.9 1.6 2 0 0 2 2 2 0 Atrophin-1 family DUF1509 PF07420.6 ETO26294.1 - 6.2 5.9 13.6 9.9 5.3 9.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) tRNA-synt_1c PF00749.16 ETO26295.1 - 1.5e-65 220.9 2.1 7.9e-40 136.4 0.0 3.1 3 0 0 3 3 3 3 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 ETO26295.1 - 2e-23 82.9 0.1 3.3e-23 82.2 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain TPP1 PF10341.4 ETO26297.1 - 0.0043 17.0 1.1 0.0087 16.0 0.1 2.0 2 0 0 2 2 2 1 Shelterin complex subunit, TPP1/ACD Senescence_reg PF04520.8 ETO26297.1 - 7.2 7.0 14.8 0.56 10.6 3.9 2.4 2 0 0 2 2 2 0 Senescence regulator RPEL PF02755.10 ETO26298.1 - 4.8e-11 41.6 16.2 0.00024 20.3 0.7 5.9 5 2 0 5 5 5 4 RPEL repeat DUF4225 PF13988.1 ETO26299.1 - 0.12 11.8 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) YniB PF14002.1 ETO26300.1 - 0.016 14.7 0.1 0.051 13.0 0.0 1.8 2 0 0 2 2 2 0 YniB-like protein GNVR PF13807.1 ETO26300.1 - 0.054 13.2 1.5 0.066 12.9 0.1 1.8 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase SCAMP PF04144.8 ETO26300.1 - 0.13 12.0 2.0 0.75 9.6 0.1 2.1 2 0 0 2 2 2 0 SCAMP family PABP PF00658.13 ETO26301.1 - 0.0012 18.4 0.0 0.0027 17.3 0.0 1.6 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain WWE PF02825.15 ETO26301.1 - 0.0037 16.6 0.2 0.018 14.4 0.1 2.3 1 0 0 1 1 1 1 WWE domain zf-CCCH PF00642.19 ETO26301.1 - 0.0063 16.1 1.4 0.0063 16.1 1.0 2.8 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TFIIF_alpha PF05793.7 ETO26302.1 - 0.15 10.4 8.3 0.17 10.1 5.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2457 PF10446.4 ETO26302.1 - 0.25 10.0 9.3 0.26 9.9 6.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pox_Ag35 PF03286.9 ETO26302.1 - 0.52 9.7 6.3 0.63 9.5 4.4 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SDA1 PF05285.7 ETO26302.1 - 1.2 8.3 8.3 1.3 8.1 5.8 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 ETO26302.1 - 2.7 5.9 5.7 3 5.7 4.0 1.0 1 0 0 1 1 1 0 CDC45-like protein PPR_2 PF13041.1 ETO26303.1 - 2e-13 50.0 6.6 1.4e-09 37.8 0.1 4.2 4 1 1 5 5 5 3 PPR repeat family PPR_3 PF13812.1 ETO26303.1 - 8.8e-13 47.4 1.9 0.00032 20.7 0.0 5.3 5 0 0 5 5 5 3 Pentatricopeptide repeat domain PPR PF01535.15 ETO26303.1 - 7.7e-12 44.3 6.4 0.00021 21.0 0.1 5.0 4 0 0 4 4 4 3 PPR repeat PPR_1 PF12854.2 ETO26303.1 - 8.6e-05 21.9 0.7 0.01 15.2 0.0 3.3 3 0 0 3 3 3 1 PPR repeat TPR_14 PF13428.1 ETO26303.1 - 0.039 14.5 0.0 27 5.7 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1216 PF06746.6 ETO26304.1 - 0.013 15.2 8.2 0.89 9.3 1.5 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1216) RPEL PF02755.10 ETO26304.1 - 0.052 12.8 21.3 18 4.8 0.1 7.5 7 0 0 7 7 7 0 RPEL repeat SAP PF02037.22 ETO26305.1 - 0.022 14.2 2.7 0.039 13.4 0.3 2.3 2 0 0 2 2 2 0 SAP domain Chal_sti_synt_N PF00195.14 ETO26306.1 - 1.3 8.1 4.1 9 5.4 0.2 2.2 2 0 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain ACCA PF03255.9 ETO26307.1 - 0.017 14.6 1.4 0.017 14.6 1.0 3.7 4 1 1 5 5 5 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit bZIP_2 PF07716.10 ETO26307.1 - 0.023 14.4 2.5 0.023 14.4 1.7 6.6 4 2 0 5 5 5 0 Basic region leucine zipper PilJ PF13675.1 ETO26307.1 - 0.024 14.9 8.6 0.026 14.8 0.2 3.5 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF1515 PF07439.6 ETO26307.1 - 0.81 9.5 14.2 0.14 11.9 0.3 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) Peptidase_M15_2 PF05951.8 ETO26307.1 - 1.4 8.3 5.2 15 4.9 0.6 2.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF882) DUF948 PF06103.6 ETO26307.1 - 9.7 6.1 9.5 5.6 6.8 0.3 3.8 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) TcdA_TcdB PF12919.2 ETO26308.1 - 0.00022 19.8 1.1 0.00034 19.2 0.8 1.2 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Leu_zip PF15294.1 ETO26308.1 - 0.00066 18.8 3.1 0.0013 17.9 2.2 1.4 1 0 0 1 1 1 1 Leucine zipper ERM PF00769.14 ETO26308.1 - 0.00077 19.0 6.5 0.0014 18.2 4.5 1.4 1 0 0 1 1 1 1 Ezrin/radixin/moesin family IncA PF04156.9 ETO26308.1 - 0.0064 16.1 4.5 0.01 15.4 3.1 1.4 1 0 0 1 1 1 1 IncA protein NAD_binding_1 PF00175.16 ETO26308.1 - 0.0084 16.6 0.1 0.015 15.8 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Colipase-like PF15083.1 ETO26309.1 - 1.4 8.8 6.2 2.1 8.3 0.7 2.3 1 1 1 2 2 2 0 Colipase-like DUF3837 PF12939.2 ETO26310.1 - 0.0067 16.4 0.4 0.019 14.9 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3837) UPF0547 PF10571.4 ETO26310.1 - 0.0078 15.8 0.0 0.83 9.4 0.0 2.5 2 1 0 2 2 2 1 Uncharacterised protein family UPF0547 Borrelia_lipo_1 PF05714.6 ETO26310.1 - 0.016 14.3 0.3 0.016 14.3 0.2 1.5 2 0 0 2 2 2 0 Borrelia burgdorferi virulent strain associated lipoprotein DUF342 PF03961.8 ETO26310.1 - 0.07 11.5 0.3 0.094 11.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Vps39_2 PF10367.4 ETO26310.1 - 0.083 13.0 1.8 0.13 12.4 0.1 2.0 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.1 ETO26310.1 - 0.15 11.9 0.6 0.34 10.7 0.4 1.6 1 1 0 1 1 1 0 Ring finger domain DUF1593 PF07632.6 ETO26310.1 - 0.15 11.3 0.1 0.23 10.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) Rad50_zn_hook PF04423.9 ETO26310.1 - 3.2 7.3 6.2 0.86 9.1 0.1 2.9 3 1 0 3 3 3 0 Rad50 zinc hook motif Clathrin PF00637.15 ETO26311.1 - 1.7e-07 30.9 0.2 2.7e-05 23.7 0.0 2.6 2 1 0 2 2 2 2 Region in Clathrin and VPS MA3 PF02847.12 ETO26311.1 - 0.1 12.2 0.5 0.52 10.0 0.0 2.4 3 0 0 3 3 3 0 MA3 domain CBM_4_9 PF02018.12 ETO26311.1 - 0.12 12.4 0.6 0.65 9.9 0.0 2.1 2 0 0 2 2 2 0 Carbohydrate binding domain Pep3_Vps18 PF05131.9 ETO26312.1 - 8.7e-16 57.6 1.0 1.3e-15 57.0 0.7 1.3 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family HSCB_C PF07743.8 ETO26312.1 - 0.26 11.7 1.4 1 9.8 0.5 2.1 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain TPR_2 PF07719.12 ETO26312.1 - 0.32 11.0 2.8 2.7 8.1 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF912 PF06024.7 ETO26312.1 - 1.7 8.7 5.5 3.4 7.7 3.9 1.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TRAP-gamma PF07074.7 ETO26312.1 - 2.1 7.8 8.8 7 6.1 1.9 2.1 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) YIF1 PF03878.10 ETO26313.1 - 1.6e-40 138.7 6.2 2.3e-31 108.7 1.4 2.0 2 0 0 2 2 2 2 YIF1 Yip1 PF04893.12 ETO26313.1 - 0.057 12.9 15.1 0.031 13.7 8.3 2.0 2 1 1 3 3 3 0 Yip1 domain KcnmB2_inactiv PF09303.5 ETO26313.1 - 0.13 12.0 3.6 0.31 10.8 2.5 1.7 1 0 0 1 1 1 0 KCNMB2, ball and chain domain NDUF_C2 PF06374.6 ETO26313.1 - 0.23 11.4 1.5 0.71 9.8 0.0 2.5 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) ADP_ribosyl_GH PF03747.9 ETO26314.1 - 1.9e-19 70.5 0.0 3.3e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase WD40 PF00400.27 ETO26316.1 - 3.9e-08 32.8 5.4 0.00017 21.3 0.0 4.6 4 1 0 4 4 4 2 WD domain, G-beta repeat ATG16 PF08614.6 ETO26316.1 - 4.6e-05 23.3 35.5 4.6e-05 23.3 24.6 7.1 1 1 2 5 5 4 2 Autophagy protein 16 (ATG16) Myosin_tail_1 PF01576.14 ETO26316.1 - 6.5e-05 20.8 45.4 6.5e-05 20.8 31.5 4.0 2 1 1 3 3 3 2 Myosin tail CENP-F_leu_zip PF10473.4 ETO26316.1 - 0.00014 21.7 16.0 0.00014 21.7 11.1 6.6 2 2 3 6 6 4 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.1 ETO26316.1 - 0.00066 18.2 36.6 0.00066 18.2 25.4 4.0 1 1 2 3 3 3 2 AAA domain TMF_TATA_bd PF12325.3 ETO26316.1 - 0.00073 19.2 13.5 0.00073 19.2 9.3 7.8 1 1 6 8 8 7 3 TATA element modulatory factor 1 TATA binding DMPK_coil PF08826.5 ETO26316.1 - 0.0038 17.0 12.2 0.0038 17.0 8.4 8.4 7 2 2 9 9 7 1 DMPK coiled coil domain like SlyX PF04102.7 ETO26316.1 - 0.0051 17.1 4.5 0.0051 17.1 3.1 10.0 5 3 6 11 11 9 2 SlyX CASP_C PF08172.7 ETO26316.1 - 0.0055 15.7 12.6 0.0055 15.7 8.7 6.3 3 3 0 5 5 4 1 CASP C terminal DUF1664 PF07889.7 ETO26316.1 - 0.009 15.8 6.7 0.009 15.8 4.7 7.8 2 2 6 8 8 8 1 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 ETO26316.1 - 0.012 14.7 39.3 0.1 11.7 6.3 5.3 1 1 3 5 5 5 0 Reovirus sigma C capsid protein DUF3639 PF12341.3 ETO26316.1 - 0.32 11.0 1.5 0.5 10.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3639) DUF3675 PF12428.3 ETO26316.1 - 0.8 9.9 6.1 0.45 10.7 0.2 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3675) Baculo_PEP_C PF04513.7 ETO26316.1 - 0.96 9.2 66.7 0.011 15.5 7.7 6.0 2 2 2 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUSC PF04632.7 ETO26316.1 - 1.1 7.5 15.9 0.89 7.9 0.7 2.9 3 0 0 3 3 3 0 Fusaric acid resistance protein family MscS_porin PF12795.2 ETO26316.1 - 1.4 8.1 104.8 0.029 13.7 9.9 6.0 3 1 3 6 6 6 0 Mechanosensitive ion channel porin domain Filament PF00038.16 ETO26316.1 - 2.7 7.3 107.1 0.092 12.1 13.7 5.4 2 2 1 4 4 3 0 Intermediate filament protein TPR_MLP1_2 PF07926.7 ETO26316.1 - 2.8 7.6 124.0 0.035 13.8 14.1 6.5 2 2 3 6 6 6 0 TPR/MLP1/MLP2-like protein DUF3584 PF12128.3 ETO26316.1 - 9.9 3.3 102.5 0.0023 15.3 33.9 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) WD40 PF00400.27 ETO26317.1 - 7.4e-71 231.7 16.0 3.3e-14 52.1 0.1 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO26317.1 - 2.1e-10 40.6 0.0 0.00049 19.8 0.0 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO26317.1 - 8.7e-10 37.3 4.1 0.0044 15.2 0.0 4.3 1 1 3 4 4 4 4 Nucleoporin Nup120/160 B_lectin PF01453.19 ETO26317.1 - 2.7e-05 24.0 0.1 0.022 14.6 0.0 2.5 1 1 1 3 3 3 2 D-mannose binding lectin Cytochrom_D1 PF02239.11 ETO26317.1 - 4.4e-05 21.9 1.1 0.022 13.0 0.0 3.1 1 1 2 3 3 3 2 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO26317.1 - 4.6e-05 22.6 0.3 0.48 9.4 0.0 3.9 1 1 3 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Resistin PF06954.6 ETO26317.1 - 0.0013 18.9 0.0 30 4.9 0.0 4.0 2 1 2 4 4 4 0 Resistin PD40 PF07676.7 ETO26317.1 - 0.047 13.3 4.9 31 4.3 0.0 4.9 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat PARP PF00644.15 ETO26318.1 - 1e-05 25.0 0.7 4.2e-05 23.0 0.0 2.3 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain SUKH_6 PF14568.1 ETO26318.1 - 0.14 12.6 2.2 0.23 11.9 0.1 2.3 2 1 0 2 2 2 0 SMI1-KNR4 cell-wall TarH PF02203.10 ETO26320.1 - 1.2 8.9 5.9 4.2 7.1 4.1 1.9 1 0 0 1 1 1 0 Tar ligand binding domain homologue Desmo_N PF06771.6 ETO26321.1 - 0.015 15.1 0.1 0.051 13.4 0.1 1.9 1 0 0 1 1 1 0 Viral Desmoplakin N-terminus DUF4455 PF14643.1 ETO26321.1 - 0.025 13.2 1.7 0.038 12.6 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4455) His_Phos_1 PF00300.17 ETO26322.1 - 7.1e-22 78.1 0.6 8.6e-22 77.9 0.4 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 ETO26322.1 - 0.00011 21.6 0.1 0.00012 21.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF4346 PF14251.1 ETO26322.1 - 0.0035 17.0 0.1 0.0069 16.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4346) RraB PF06877.6 ETO26322.1 - 0.044 14.4 0.3 0.085 13.5 0.2 1.5 1 0 0 1 1 1 0 Regulator of ribonuclease activity B NAD_binding_6 PF08030.7 ETO26323.1 - 4.8e-09 36.2 0.7 0.00038 20.3 0.0 3.1 2 1 1 3 3 3 3 Ferric reductase NAD binding domain AAA PF00004.24 ETO26325.1 - 3e-31 108.3 0.4 4.6e-29 101.2 0.3 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 ETO26325.1 - 1.2e-05 25.0 0.0 4.7e-05 23.1 0.0 2.0 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.9 ETO26325.1 - 9.1e-05 22.2 0.5 0.0014 18.3 0.3 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETO26325.1 - 0.00096 19.3 0.0 0.0033 17.5 0.0 2.0 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 ETO26325.1 - 0.0032 16.6 0.0 0.0063 15.6 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 ETO26325.1 - 0.0034 16.9 0.0 0.0062 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETO26325.1 - 0.0058 16.3 0.2 0.024 14.4 0.1 2.0 2 0 0 2 2 2 1 Part of AAA domain Sigma54_activat PF00158.21 ETO26325.1 - 0.01 15.3 0.4 0.098 12.1 0.3 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 ETO26325.1 - 0.011 15.2 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETO26325.1 - 0.016 15.2 0.2 0.071 13.0 0.2 2.2 1 1 1 2 2 2 0 AAA ATPase domain AAA_2 PF07724.9 ETO26325.1 - 0.017 15.0 0.0 0.063 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 ETO26325.1 - 0.021 14.7 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 ETO26325.1 - 0.032 13.6 0.1 0.11 11.9 0.0 2.0 2 1 1 3 3 3 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 ETO26325.1 - 0.037 13.1 0.0 0.071 12.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.1 ETO26325.1 - 0.037 13.9 0.0 0.098 12.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 ETO26325.1 - 0.056 12.5 0.6 1.3 8.0 0.3 2.8 1 1 0 1 1 1 0 KaiC AAA_25 PF13481.1 ETO26325.1 - 0.11 11.9 0.2 0.32 10.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 ETO26325.1 - 0.12 12.6 0.0 0.41 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain PTPlike_phytase PF14566.1 ETO26326.1 - 7e-30 104.0 0.1 1.7e-21 76.8 0.0 2.6 2 0 0 2 2 2 2 Inositol hexakisphosphate CAP_GLY PF01302.20 ETO26327.1 - 6.5e-21 73.8 0.1 1.3e-20 72.8 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain Trypan_PARP PF05887.6 ETO26327.1 - 2e-06 27.6 24.4 2e-06 27.6 16.9 2.2 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) DUF3043 PF11241.3 ETO26327.1 - 0.7 9.4 3.5 1.5 8.4 2.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3043) Neisseria_TspB PF05616.8 ETO26327.1 - 8.9 4.5 16.4 17 3.6 11.4 1.4 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein PKI PF02827.11 ETO26328.1 - 2.1 8.5 8.3 0.99 9.5 2.6 2.3 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor 7TM-7TMR_HD PF07698.6 ETO26329.1 - 0.00013 21.4 0.4 0.00013 21.4 0.3 1.5 2 0 0 2 2 2 1 7TM receptor with intracellular HD hydrolase YfhO PF09586.5 ETO26329.1 - 0.00032 18.8 1.1 0.00045 18.3 0.8 1.1 1 0 0 1 1 1 1 Bacterial membrane protein YfhO DUF3366 PF11846.3 ETO26329.1 - 0.12 12.2 8.0 1.7 8.4 0.6 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3366) GWT1 PF06423.7 ETO26329.1 - 0.39 10.8 4.5 0.79 9.8 3.1 1.6 1 1 0 1 1 1 0 GWT1 Ctr PF04145.10 ETO26329.1 - 0.9 9.5 4.7 0.75 9.8 0.5 2.2 2 0 0 2 2 2 0 Ctr copper transporter family SHR3_chaperone PF08229.6 ETO26329.1 - 1.2 8.0 8.2 2.7 6.8 5.7 1.6 1 0 0 1 1 1 0 ER membrane protein SH3 TPR_11 PF13414.1 ETO26330.1 - 3e-21 74.8 21.2 4.7e-07 29.3 1.6 5.5 4 1 1 5 5 5 4 TPR repeat TPR_2 PF07719.12 ETO26330.1 - 1.2e-17 62.3 21.5 0.0072 16.1 0.6 8.0 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.1 ETO26330.1 - 9.7e-16 57.4 19.2 3.7e-06 26.7 0.7 5.5 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO26330.1 - 3.7e-11 42.3 21.8 0.01 15.9 0.0 6.6 6 1 0 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO26330.1 - 4e-10 40.1 4.5 3.7e-06 27.4 0.1 4.2 3 1 1 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO26330.1 - 5.5e-09 35.8 0.9 0.38 11.5 0.0 4.9 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO26330.1 - 2.8e-08 33.0 24.5 0.0036 16.8 0.1 7.7 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO26330.1 - 3.3e-06 26.4 26.1 0.035 13.8 0.1 7.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO26330.1 - 2e-05 24.0 17.6 2.2 8.2 0.0 7.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO26330.1 - 0.00015 21.9 4.3 0.77 10.3 0.0 5.3 4 0 0 4 4 4 1 Tetratricopeptide repeat Rtf2 PF04641.7 ETO26330.1 - 0.002 17.3 2.5 0.002 17.3 1.7 3.0 3 1 0 3 3 2 1 Rtf2 RING-finger TPR_5 PF12688.2 ETO26330.1 - 0.035 14.1 0.3 0.18 11.8 0.0 2.4 3 0 0 3 3 1 0 Tetratrico peptide repeat Ctr PF04145.10 ETO26330.1 - 0.15 12.1 8.3 0.13 12.2 0.8 3.1 3 0 0 3 3 3 0 Ctr copper transporter family Herpes_UL3 PF03369.8 ETO26330.1 - 0.3 11.0 3.3 0.81 9.6 2.3 1.7 1 0 0 1 1 1 0 Herpesvirus UL3 protein Serinc PF03348.10 ETO26330.1 - 1.5 7.4 12.7 0.046 12.4 2.5 2.3 2 0 0 2 2 2 0 Serine incorporator (Serinc) Nop14 PF04147.7 ETO26330.1 - 2.1 6.1 62.3 1.1 7.1 23.2 2.4 2 0 0 2 2 2 0 Nop14-like family SDA1 PF05285.7 ETO26330.1 - 2.6 7.2 65.3 0.054 12.7 7.8 2.7 2 1 0 2 2 2 0 SDA1 TFIIA PF03153.8 ETO26330.1 - 8.7 6.1 64.7 0.55 10.0 2.0 3.3 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit DUF3492 PF11997.3 ETO26330.1 - 9.8 5.6 12.5 6.3 6.2 3.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3492) DUF913 PF06025.7 ETO26331.1 - 6.2e-18 64.7 0.0 6.2e-18 64.7 0.0 1.5 2 0 0 2 2 2 1 Domain of Unknown Function (DUF913) DUF1884 PF08967.5 ETO26332.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1884) ELF PF03317.8 ETO26332.1 - 5.1 6.3 10.1 8.3 5.6 7.0 1.4 1 0 0 1 1 1 0 ELF protein SOG2 PF10428.4 ETO26333.1 - 0.0069 15.0 0.2 0.017 13.8 0.1 1.6 2 0 0 2 2 2 1 RAM signalling pathway protein SH3_9 PF14604.1 ETO26334.1 - 2.2e-15 55.9 0.1 3.6e-15 55.2 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 ETO26334.1 - 1.7e-14 53.0 0.2 3.1e-14 52.1 0.0 1.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 ETO26334.1 - 4e-14 51.7 0.1 6.7e-14 51.0 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.6 ETO26334.1 - 0.087 13.0 0.4 0.43 10.8 0.1 2.0 2 0 0 2 2 2 0 Bacterial SH3 domain DUF3278 PF11683.3 ETO26335.1 - 0.029 14.3 0.2 0.04 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) SPRY PF00622.23 ETO26336.1 - 7.6e-15 55.0 0.8 1.9e-14 53.8 0.5 1.7 1 0 0 1 1 1 1 SPRY domain Exo_endo_phos PF03372.18 ETO26338.1 - 1.6e-12 47.9 0.0 2.2e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SET PF00856.23 ETO26339.1 - 6.7e-24 85.0 0.3 2.6e-23 83.1 0.2 1.9 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 ETO26339.1 - 0.86 9.9 10.4 0.4 10.9 3.7 2.3 2 0 0 2 2 2 0 Pre-SET motif WD40 PF00400.27 ETO26340.1 - 7.8e-11 41.4 2.8 6.7e-08 32.1 0.8 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat zf-TRAF PF02176.13 ETO26341.1 - 4.2e-05 23.8 5.2 6.5e-05 23.2 2.1 2.5 2 0 0 2 2 2 1 TRAF-type zinc finger DUF3753 PF12575.3 ETO26341.1 - 0.24 11.2 0.1 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) zf-BED PF02892.10 ETO26341.1 - 0.59 9.9 4.6 1.6 8.5 0.3 3.3 3 0 0 3 3 3 0 BED zinc finger Tubulin PF00091.20 ETO26343.1 - 8.4e-68 228.4 0.0 1.3e-67 227.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO26343.1 - 1.6e-28 99.2 0.0 2.5e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 ETO26343.1 - 0.0012 18.8 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.1 ETO26343.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Tubulin like GPS PF01825.16 ETO26344.1 - 1.5e-08 34.5 2.6 6.7e-08 32.5 1.8 2.2 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain Mucin PF01456.12 ETO26344.1 - 0.015 15.0 23.5 0.05 13.3 16.3 1.9 1 0 0 1 1 1 0 Mucin-like glycoprotein Peptidase_A24 PF01478.13 ETO26345.1 - 0.054 13.6 3.6 0.028 14.5 1.0 1.8 2 1 0 2 2 2 0 Type IV leader peptidase family Bap31 PF05529.7 ETO26345.1 - 0.085 12.3 1.3 0.18 11.2 0.9 1.6 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Adeno_E3_CR2 PF02439.10 ETO26345.1 - 0.12 11.9 0.5 2.8 7.5 0.0 2.5 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 DUF457 PF04307.9 ETO26345.1 - 2.4 7.4 5.3 1.5 8.1 2.2 1.6 1 1 1 2 2 2 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) DUF1722 PF08349.6 ETO26346.1 - 0.068 13.0 1.2 0.18 11.6 0.1 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1722) Sigma70_ner PF04546.8 ETO26346.1 - 0.12 12.0 6.5 0.2 11.2 4.5 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region FAM176 PF14851.1 ETO26346.1 - 0.21 11.2 2.4 0.47 10.1 1.6 1.7 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.1 ETO26346.1 - 3.1 8.1 13.0 11 6.3 9.0 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.6 ETO26346.1 - 5.2 6.8 17.0 1.4 8.7 8.3 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal CobD_Cbib PF03186.8 ETO26347.1 - 0.084 11.9 0.1 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 CobD/Cbib protein Nse4-Nse3_bdg PF15412.1 ETO26348.1 - 0.091 12.6 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 Binding domain of Nse4/EID3 to Nse3-MAGE Ras PF00071.17 ETO26349.1 - 9.7e-15 54.3 1.2 3.5e-14 52.5 0.1 2.0 2 0 0 2 2 2 1 Ras family WD40 PF00400.27 ETO26350.1 - 4.1e-68 223.0 24.3 7.8e-13 47.7 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO26350.1 - 4.3e-13 48.2 2.8 0.0015 16.7 0.0 5.2 3 1 2 5 5 5 5 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO26350.1 - 5.2e-06 26.7 1.4 5.2e-06 26.7 1.0 2.1 2 0 0 2 2 2 1 TRAF-type zinc finger TBPIP PF07106.8 ETO26350.1 - 2.4 7.6 20.0 1.9 7.9 9.8 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4247 PF14042.1 ETO26352.1 - 0.019 14.9 0.1 0.058 13.3 0.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4247) DUF296 PF03479.10 ETO26352.1 - 0.056 13.0 0.1 0.11 12.1 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF296) DUF1067 PF06362.6 ETO26352.1 - 0.098 13.2 2.4 0.13 12.7 0.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1067) THDPS_N PF14790.1 ETO26352.1 - 0.11 12.0 1.5 0.22 11.1 1.1 1.4 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal 5_3_exonuc_N PF02739.11 ETO26352.1 - 0.18 11.1 2.1 0.25 10.7 0.6 1.8 2 0 0 2 2 2 0 5'-3' exonuclease, N-terminal resolvase-like domain Mito_carr PF00153.22 ETO26355.1 - 3.7e-31 106.6 2.9 8.4e-23 79.9 0.2 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF3704 PF12488.3 ETO26355.1 - 1.6 8.4 4.3 0.9 9.1 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3704) Sec15 PF04091.7 ETO26356.1 - 2.8e-35 122.1 4.1 2.8e-27 95.8 0.7 2.4 2 1 0 2 2 2 2 Exocyst complex subunit Sec15-like DUF3439 PF11921.3 ETO26357.1 - 0.026 14.2 6.5 0.033 13.9 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) YL1 PF05764.8 ETO26357.1 - 0.17 11.4 36.4 0.21 11.1 25.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein OAD_gamma PF04277.8 ETO26358.1 - 1.3 9.4 4.9 0.33 11.3 0.5 2.0 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF2852 PF11014.3 ETO26360.1 - 0.023 14.6 1.0 0.05 13.5 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) Fijivirus_P9-2 PF06837.6 ETO26360.1 - 0.053 12.6 2.2 3.8 6.5 1.1 2.2 2 0 0 2 2 2 0 Fijivirus P9-2 protein ETRAMP PF09716.5 ETO26360.1 - 0.12 12.3 3.9 40 4.2 0.0 3.0 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) SID-1_RNA_chan PF13965.1 ETO26360.1 - 0.19 9.8 5.8 0.12 10.4 0.4 2.0 1 1 1 2 2 2 0 dsRNA-gated channel SID-1 DUF4512 PF14975.1 ETO26360.1 - 3 8.7 5.9 0.8 10.5 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4512) SASP_gamma PF04259.9 ETO26361.1 - 0.067 13.3 4.0 0.77 9.9 2.2 2.2 1 1 1 2 2 2 0 Small, acid-soluble spore protein, gamma-type MS_channel PF00924.13 ETO26362.1 - 0.079 12.2 0.4 0.13 11.5 0.3 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel Adeno_shaft PF00608.12 ETO26362.1 - 0.12 12.0 0.5 0.26 10.9 0.3 1.6 1 0 0 1 1 1 0 Adenoviral fibre protein (repeat/shaft region) Mem_trans PF03547.13 ETO26362.1 - 7.9 4.6 7.0 11 4.1 4.9 1.4 1 1 0 1 1 1 0 Membrane transport protein GILT PF03227.11 ETO26363.1 - 3e-18 65.6 1.3 3.9e-18 65.3 0.4 1.5 1 1 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) EI24 PF07264.6 ETO26367.1 - 5.2e-05 22.7 0.3 5.2e-05 22.7 0.2 1.5 2 0 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) Methyltransf_25 PF13649.1 ETO26370.1 - 0.025 14.9 0.1 0.17 12.2 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain GST_C PF00043.20 ETO26371.1 - 3.9e-09 36.3 0.1 4.7e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETO26371.1 - 1.5e-05 24.8 0.0 1.7e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 ETO26371.1 - 4.8e-05 23.7 0.0 6.3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain rve_3 PF13683.1 ETO26371.1 - 0.13 11.8 0.2 0.28 10.7 0.1 1.6 1 0 0 1 1 1 0 Integrase core domain CytochromB561_N PF09786.4 ETO26372.1 - 0.074 11.4 14.7 0.083 11.3 10.2 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal Neur_chan_memb PF02932.11 ETO26372.1 - 0.13 12.1 12.7 0.19 11.5 8.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Anoctamin PF04547.7 ETO26372.1 - 0.19 10.3 4.0 0.24 10.0 2.8 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel SID-1_RNA_chan PF13965.1 ETO26372.1 - 0.35 8.9 7.0 0.38 8.8 4.8 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CDC45 PF02724.9 ETO26372.1 - 0.51 8.3 10.0 0.55 8.1 6.9 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 ETO26372.1 - 2 7.9 24.0 2.7 7.5 16.6 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Mem_trans PF03547.13 ETO26372.1 - 4.1 5.5 15.2 6.2 5.0 10.5 1.4 1 1 0 1 1 1 0 Membrane transport protein DUF1314 PF07013.6 ETO26372.1 - 6.8 6.0 7.5 1.3 8.3 1.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1314) Peptidase_C14 PF00656.17 ETO26373.1 - 9.7e-10 38.5 1.9 1.2e-09 38.2 1.3 1.1 1 0 0 1 1 1 1 Caspase domain Phage_int_SAM_4 PF13495.1 ETO26373.1 - 0.16 12.2 1.4 0.55 10.5 0.1 2.2 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain zf-TRAF PF02176.13 ETO26374.1 - 0.00051 20.3 1.5 0.00051 20.3 1.0 2.8 2 0 0 2 2 2 1 TRAF-type zinc finger zf-RING_2 PF13639.1 ETO26374.1 - 2 8.2 6.7 0.4 10.5 1.1 2.6 2 1 0 2 2 2 0 Ring finger domain Phosphoesterase PF04185.9 ETO26375.1 - 5e-24 85.2 0.2 2e-23 83.2 0.1 1.8 1 1 0 1 1 1 1 Phosphoesterase family Amidase PF01425.16 ETO26376.1 - 0.27 10.0 3.2 0.61 8.8 2.2 1.5 1 0 0 1 1 1 0 Amidase Neur_chan_memb PF02932.11 ETO26378.1 - 0.0021 18.0 1.6 0.0023 17.8 1.1 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.17 ETO26378.1 - 0.0063 15.5 5.5 0.0074 15.3 3.8 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter SID-1_RNA_chan PF13965.1 ETO26378.1 - 0.047 11.8 0.8 0.053 11.6 0.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 BTV_NS2 PF04514.7 ETO26378.1 - 0.17 10.7 10.5 0.19 10.5 7.3 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Ctr PF04145.10 ETO26378.1 - 0.19 11.7 1.5 0.48 10.4 1.0 1.7 1 1 0 1 1 1 0 Ctr copper transporter family GEMIN8 PF15348.1 ETO26378.1 - 0.3 11.1 11.4 0.37 10.7 7.9 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Ycf1 PF05758.7 ETO26378.1 - 0.45 8.1 3.8 0.49 8.0 2.6 1.0 1 0 0 1 1 1 0 Ycf1 Presenilin PF01080.12 ETO26378.1 - 0.64 8.7 4.8 0.76 8.5 3.3 1.1 1 0 0 1 1 1 0 Presenilin Trypan_PARP PF05887.6 ETO26378.1 - 0.65 9.8 11.2 0.78 9.5 7.7 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3796 PF12676.2 ETO26378.1 - 0.85 9.8 8.4 1.2 9.4 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) ANAPC15 PF15243.1 ETO26378.1 - 0.97 9.5 13.7 1.3 9.1 9.5 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Dynactin_p22 PF07426.6 ETO26378.1 - 1 8.5 3.9 0.75 9.0 1.6 1.4 1 1 0 1 1 1 0 Dynactin subunit p22 DUF1510 PF07423.6 ETO26378.1 - 1.5 8.1 12.9 1.8 7.8 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 ETO26378.1 - 3.1 5.7 9.3 3.6 5.4 6.5 1.0 1 0 0 1 1 1 0 CDC45-like protein GAGA_bind PF06217.7 ETO26378.1 - 3.2 7.6 7.5 3.7 7.4 5.2 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Daxx PF03344.10 ETO26378.1 - 3.4 6.0 17.5 4.2 5.7 12.1 1.0 1 0 0 1 1 1 0 Daxx Family RR_TM4-6 PF06459.7 ETO26378.1 - 3.7 7.3 12.5 4.3 7.1 8.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HSP90 PF00183.13 ETO26378.1 - 6.4 5.0 11.3 7.1 4.9 7.8 1.1 1 0 0 1 1 1 0 Hsp90 protein PPP4R2 PF09184.6 ETO26378.1 - 8.5 5.8 17.0 10 5.6 11.8 1.0 1 0 0 1 1 1 0 PPP4R2 BUD22 PF09073.5 ETO26379.1 - 6.4 5.7 19.8 7.2 5.5 13.7 1.0 1 0 0 1 1 1 0 BUD22 TT_ORF2 PF02957.10 ETO26380.1 - 0.23 12.1 0.3 0.23 12.1 0.2 1.5 2 0 0 2 2 2 0 TT viral ORF2 peroxidase PF00141.18 ETO26381.1 - 2.9e-35 121.8 0.0 4.3e-35 121.2 0.0 1.3 1 1 0 1 1 1 1 Peroxidase NAPRTase PF04095.11 ETO26382.1 - 6.7e-19 68.1 0.0 1e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family Methyltransf_1N PF02870.10 ETO26383.1 - 6.2 7.4 13.0 34 5.1 0.1 4.8 4 0 0 4 4 4 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain WD40 PF00400.27 ETO26384.1 - 8.5e-13 47.6 1.5 2.9e-06 26.9 0.0 3.9 3 1 0 3 3 3 3 WD domain, G-beta repeat DUF4556 PF15094.1 ETO26384.1 - 0.059 12.9 0.1 0.77 9.2 0.0 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4556) NAPRTase PF04095.11 ETO26385.1 - 4.4e-12 45.7 0.2 7.9e-12 44.9 0.0 1.5 2 0 0 2 2 2 1 Nicotinate phosphoribosyltransferase (NAPRTase) family QRPTase_N PF02749.11 ETO26385.1 - 0.006 16.3 0.0 0.014 15.2 0.0 1.6 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain DUF1829 PF08862.5 ETO26385.1 - 0.28 11.4 2.1 0.28 11.5 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF1829 Reo_sigmaC PF04582.7 ETO26386.1 - 2.9e-05 23.4 11.3 0.0025 17.0 0.3 3.0 1 1 2 3 3 3 3 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 ETO26386.1 - 7e-05 22.7 63.5 0.012 15.5 13.3 3.4 2 1 1 3 3 3 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 ETO26386.1 - 0.00051 17.9 55.3 0.0047 14.7 14.7 2.3 1 1 0 1 1 1 1 Myosin tail APG6 PF04111.7 ETO26386.1 - 0.0011 18.0 57.2 0.038 13.0 10.6 3.1 1 1 2 3 3 3 3 Autophagy protein Apg6 IncA PF04156.9 ETO26386.1 - 0.003 17.1 58.6 0.021 14.3 10.7 4.0 1 1 2 3 3 3 2 IncA protein Seryl_tRNA_N PF02403.17 ETO26386.1 - 0.0064 16.4 53.4 0.056 13.4 3.9 4.8 1 1 4 5 5 5 3 Seryl-tRNA synthetase N-terminal domain HAMP PF00672.20 ETO26386.1 - 0.038 14.1 0.7 0.83 9.8 0.1 2.6 2 0 0 2 2 2 0 HAMP domain NPV_P10 PF05531.7 ETO26386.1 - 0.054 13.7 0.4 0.054 13.7 0.3 5.6 3 3 2 5 5 5 0 Nucleopolyhedrovirus P10 protein ERM PF00769.14 ETO26386.1 - 0.066 12.7 57.6 1.2 8.5 10.2 3.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family AAA_13 PF13166.1 ETO26386.1 - 0.068 11.6 40.2 0.21 10.0 16.6 2.1 1 1 1 2 2 2 0 AAA domain GAS PF13851.1 ETO26386.1 - 0.071 12.2 60.8 0.066 12.3 11.8 3.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding AAA_27 PF13514.1 ETO26386.1 - 0.1 10.2 40.8 0.0089 13.7 20.2 1.9 1 1 1 2 2 2 0 AAA domain TBPIP PF07106.8 ETO26386.1 - 0.22 11.0 53.3 1.3 8.5 10.0 4.3 1 1 3 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) BRE1 PF08647.6 ETO26386.1 - 0.35 10.8 55.4 0.045 13.7 3.4 4.5 2 1 2 4 4 4 0 BRE1 E3 ubiquitin ligase HSCB_C PF07743.8 ETO26386.1 - 0.51 10.8 40.4 0.6 10.6 3.1 5.4 4 2 1 5 5 5 0 HSCB C-terminal oligomerisation domain DUF4201 PF13870.1 ETO26386.1 - 0.58 9.5 51.6 0.041 13.3 10.3 3.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) DASH_Hsk3 PF08227.6 ETO26386.1 - 0.75 10.0 14.7 0.88 9.8 0.1 4.9 5 0 0 5 5 4 0 DASH complex subunit Hsk3 like DUF2968 PF11180.3 ETO26386.1 - 0.8 9.0 36.9 0.21 10.9 1.5 4.3 1 1 3 4 4 4 0 Protein of unknown function (DUF2968) HrpB7 PF09486.5 ETO26386.1 - 0.86 9.5 23.3 4.5 7.1 5.2 4.4 1 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) Ax_dynein_light PF10211.4 ETO26386.1 - 1.5 8.6 52.3 0.35 10.6 3.1 4.5 1 1 3 4 4 4 0 Axonemal dynein light chain Lectin_N PF03954.9 ETO26386.1 - 1.5 8.2 23.5 0.1 12.0 0.5 4.3 1 1 2 4 4 3 0 Hepatic lectin, N-terminal domain CALCOCO1 PF07888.6 ETO26386.1 - 1.5 6.9 49.1 1.5 7.0 1.9 2.8 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF972 PF06156.8 ETO26386.1 - 1.9 8.8 49.6 0.55 10.6 4.5 5.1 1 1 3 4 4 4 0 Protein of unknown function (DUF972) Filament PF00038.16 ETO26386.1 - 2.5 7.4 49.5 0.18 11.2 7.6 3.3 1 1 0 2 2 2 0 Intermediate filament protein MtrG PF04210.8 ETO26386.1 - 4.2 7.1 8.8 6.7 6.4 0.2 4.0 2 1 1 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G Spc7 PF08317.6 ETO26386.1 - 4.8 5.7 51.6 4.5 5.8 15.7 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein TMCO5 PF14992.1 ETO26386.1 - 4.9 6.1 55.2 2.3 7.2 9.1 2.5 1 1 1 2 2 2 0 TMCO5 family TPR_MLP1_2 PF07926.7 ETO26386.1 - 9.6 5.9 56.1 23 4.7 12.0 4.2 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein RasGEF PF00617.14 ETO26387.1 - 9.1e-26 90.7 0.0 5e-24 85.0 0.0 2.5 1 1 0 1 1 1 1 RasGEF domain TrkA_N PF02254.13 ETO26387.1 - 0.084 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Mucin PF01456.12 ETO26387.1 - 1.1 9.0 18.2 5.3 6.8 12.6 2.0 1 1 0 1 1 1 0 Mucin-like glycoprotein SSXT PF05030.7 ETO26388.1 - 0.055 13.0 1.1 0.077 12.5 0.1 1.8 2 0 0 2 2 2 0 SSXT protein (N-terminal region) PPP1R35_C PF15503.1 ETO26388.1 - 0.062 12.8 0.3 0.18 11.3 0.1 1.8 1 1 1 2 2 2 0 Protein phosphatase 1 regulatory subunit 35 C-terminus TPR_12 PF13424.1 ETO26389.1 - 3.2e-12 46.1 15.6 0.0033 17.3 0.1 7.1 4 3 2 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO26389.1 - 4.1e-11 42.3 19.4 0.027 14.1 0.0 6.8 6 1 0 6 6 6 3 TPR repeat TPR_1 PF00515.23 ETO26389.1 - 1.8e-05 24.1 17.0 0.00016 21.0 0.8 6.1 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO26389.1 - 2.6e-05 24.3 1.4 0.09 13.2 0.0 5.0 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO26389.1 - 7.5e-05 22.3 27.8 0.00079 19.1 0.3 8.8 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO26389.1 - 0.00015 21.2 7.3 0.0098 15.6 0.1 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO26389.1 - 0.00016 21.2 16.0 0.0012 18.4 0.4 6.6 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO26389.1 - 0.00048 20.5 0.0 51 4.8 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETO26389.1 - 0.00087 19.9 0.3 6.5 7.5 0.0 5.1 5 1 1 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO26389.1 - 0.38 10.9 20.8 4.4 7.5 0.2 6.1 5 1 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Wzy_C PF04932.10 ETO26389.1 - 2.4 7.9 5.7 5.6 6.7 4.0 1.7 1 0 0 1 1 1 0 O-Antigen ligase PK PF00224.16 ETO26390.1 - 5.3e-05 22.0 0.3 0.00012 20.8 0.0 1.7 2 0 0 2 2 2 1 Pyruvate kinase, barrel domain Surface_antigen PF11054.3 ETO26390.1 - 0.092 12.1 1.1 0.84 8.9 0.0 2.4 1 1 1 2 2 2 0 Sporozoite TA4 surface antigen Ubiq-Cytc-red_N PF09165.5 ETO26391.1 - 0.052 13.8 3.8 0.2 12.0 2.6 2.1 1 1 0 1 1 1 0 Ubiquinol-cytochrome c reductase 8 kDa, N-terminal Activator_LAG-3 PF11498.3 ETO26391.1 - 2.1 6.9 38.3 2.5 6.7 26.5 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 HlyD_2 PF12700.2 ETO26391.1 - 2.3 7.3 11.0 2.6 7.0 7.6 1.2 1 0 0 1 1 1 0 HlyD family secretion protein AAA_23 PF13476.1 ETO26391.1 - 2.6 8.3 10.8 3 8.1 7.5 1.1 1 0 0 1 1 1 0 AAA domain DUF743 PF05332.6 ETO26391.1 - 4.8 7.1 13.3 0.91 9.5 6.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF743) PAT1 PF09770.4 ETO26391.1 - 5.5 5.0 35.4 5.7 5.0 24.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CAP_GLY PF01302.20 ETO26392.1 - 8.7e-06 25.3 0.2 1.4e-05 24.6 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF4367 PF14285.1 ETO26392.1 - 0.25 10.6 7.6 0.4 9.9 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4367) TFIIA PF03153.8 ETO26392.1 - 1.3 8.8 25.7 2 8.1 17.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF106 PF01956.11 ETO26392.1 - 7.6 6.0 7.4 0.63 9.5 0.3 2.2 1 1 1 2 2 2 0 Integral membrane protein DUF106 PH PF00169.24 ETO26393.1 - 1.7e-07 31.3 0.5 1.7e-07 31.3 0.4 1.9 2 0 0 2 2 2 1 PH domain Methyltransf_12 PF08242.7 ETO26393.1 - 0.0093 16.4 3.4 0.0093 16.4 2.3 3.1 3 0 0 3 3 3 1 Methyltransferase domain PH_6 PF15406.1 ETO26393.1 - 0.013 15.5 0.1 0.046 13.7 0.1 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.1 ETO26393.1 - 0.22 11.7 6.7 0.072 13.3 1.8 2.4 2 1 0 2 2 2 0 Pleckstrin homology domain WD40 PF00400.27 ETO26394.1 - 1.2e-10 40.8 0.8 3.1e-05 23.6 0.2 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat tRNA-synt_1 PF00133.17 ETO26394.1 - 0.026 12.5 0.1 0.035 12.1 0.0 1.2 1 1 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) Dfp1_Him1_M PF08630.5 ETO26394.1 - 0.073 12.8 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Dfp1/Him1, central region CAP_GLY PF01302.20 ETO26395.1 - 7.3e-13 48.0 0.1 1.2e-12 47.3 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain DUF904 PF06005.7 ETO26395.1 - 0.0044 17.2 2.3 0.01 16.1 1.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF904) HALZ PF02183.13 ETO26395.1 - 0.0098 15.5 6.0 0.11 12.1 1.0 2.5 1 1 1 2 2 2 2 Homeobox associated leucine zipper DUF1441 PF07278.6 ETO26395.1 - 0.01 15.5 0.0 0.024 14.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1441) HisG_C PF08029.6 ETO26395.1 - 0.036 14.0 0.0 0.086 12.7 0.0 1.6 1 0 0 1 1 1 0 HisG, C-terminal domain Ras PF00071.17 ETO26396.1 - 2.9e-20 72.2 0.0 5.9e-20 71.2 0.0 1.6 1 1 0 1 1 1 1 Ras family Miro PF08477.8 ETO26396.1 - 1.3e-07 32.0 0.0 3.2e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO26396.1 - 0.0043 16.3 0.0 0.0065 15.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO26396.1 - 0.07 12.5 0.0 0.12 11.8 0.0 1.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain TPR_12 PF13424.1 ETO26397.1 - 3.5e-22 78.1 2.2 7.2e-17 61.0 0.3 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO26397.1 - 1.1e-19 69.7 0.0 1.3e-07 31.3 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO26397.1 - 4.1e-15 55.1 8.6 6.1e-09 35.4 0.8 2.5 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 ETO26397.1 - 3e-13 48.5 12.4 0.00012 21.7 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO26397.1 - 2e-12 46.1 17.6 2.9e-06 26.6 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO26397.1 - 2.6e-07 29.9 2.3 0.07 12.9 0.1 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO26397.1 - 9.6e-06 26.1 0.1 0.044 14.4 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat zf-TRAF PF02176.13 ETO26397.1 - 1.7e-05 25.0 1.3 1.7e-05 25.0 0.9 2.3 2 0 0 2 2 1 1 TRAF-type zinc finger TPR_8 PF13181.1 ETO26397.1 - 4.9e-05 22.8 16.6 0.55 10.1 1.2 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO26397.1 - 0.00032 20.6 0.3 0.57 10.5 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO26397.1 - 0.0082 16.2 6.2 0.029 14.4 1.0 3.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 ETO26397.1 - 0.011 16.2 0.0 19 6.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO26397.1 - 0.019 14.2 0.0 1 8.6 0.0 2.8 2 0 0 2 2 2 0 SHNi-TPR TPR_6 PF13174.1 ETO26397.1 - 0.085 13.3 5.6 9.6 6.9 0.1 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat Atg14 PF10186.4 ETO26397.1 - 0.11 11.4 24.9 0.2 10.5 17.2 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ATG16 PF08614.6 ETO26397.1 - 0.15 11.8 26.3 0.023 14.5 11.0 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) APG6 PF04111.7 ETO26397.1 - 0.16 11.0 25.2 0.36 9.8 17.5 1.6 1 0 0 1 1 1 0 Autophagy protein Apg6 ERM PF00769.14 ETO26397.1 - 1.7 8.1 23.2 14 5.0 16.1 2.1 1 1 0 1 1 1 0 Ezrin/radixin/moesin family WD40 PF00400.27 ETO26398.1 - 5.1e-78 254.4 21.8 7.9e-14 50.9 0.1 7.0 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO26398.1 - 6.3e-13 48.8 0.1 4.1e-05 23.3 0.0 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO26398.1 - 1e-09 37.1 9.5 0.0089 14.2 0.0 5.5 1 1 5 6 6 6 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO26398.1 - 2.1e-09 36.1 0.8 6.7e-05 21.3 0.0 2.7 1 1 0 2 2 2 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO26398.1 - 2e-05 24.1 0.4 0.0021 17.5 0.2 2.9 1 1 2 3 3 3 1 PQQ-like domain PD40 PF07676.7 ETO26398.1 - 0.00015 21.3 6.0 5.7 6.7 0.0 4.9 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 ETO26398.1 - 0.0017 17.4 0.5 0.099 11.7 0.0 3.2 1 1 3 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Resistin PF06954.6 ETO26398.1 - 0.0044 17.2 0.3 14 6.0 0.1 3.5 2 1 1 3 3 3 0 Resistin Nucleoporin_N PF08801.6 ETO26398.1 - 0.0096 14.7 12.3 1.1 7.8 0.7 4.8 1 1 3 4 4 4 1 Nup133 N terminal like Coatomer_WDAD PF04053.9 ETO26398.1 - 0.017 13.9 1.7 0.44 9.2 0.1 2.6 1 1 2 3 3 3 0 Coatomer WD associated region DUF1258 PF06869.7 ETO26398.1 - 0.02 13.9 1.3 0.29 10.1 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1258) DUF4221 PF13970.1 ETO26398.1 - 0.034 13.4 0.2 3 7.0 0.0 3.0 1 1 1 3 3 3 0 Domain of unknown function (DUF4221) DUF1797 PF08796.5 ETO26398.1 - 0.076 12.8 0.0 2.4 8.0 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1797) Proteasome_A_N PF10584.4 ETO26398.1 - 0.87 8.9 6.5 7.9 5.9 0.0 4.0 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 ETO26399.1 - 6.1e-73 238.3 17.2 9.2e-12 44.3 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO26399.1 - 2.1e-09 36.0 4.2 0.15 10.1 0.0 5.4 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO26399.1 - 7.2e-09 34.4 1.3 9.7e-05 20.8 0.1 3.0 2 1 1 3 3 3 3 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO26399.1 - 2.1e-06 26.7 19.5 0.26 9.9 0.2 6.4 2 1 3 6 6 6 5 Nup133 N terminal like PQQ_2 PF13360.1 ETO26399.1 - 1e-05 25.1 0.1 0.0013 18.2 0.0 2.4 1 1 0 2 2 2 1 PQQ-like domain Resistin PF06954.6 ETO26399.1 - 1.6e-05 25.0 2.4 10 6.4 0.0 5.4 4 2 2 6 6 6 1 Resistin Str_synth PF03088.11 ETO26399.1 - 5.4e-05 23.1 1.0 0.98 9.5 0.0 3.8 2 1 2 4 4 4 2 Strictosidine synthase Coatomer_WDAD PF04053.9 ETO26399.1 - 0.0005 18.9 7.7 0.34 9.6 0.1 3.1 1 1 0 2 2 2 2 Coatomer WD associated region DUF1258 PF06869.7 ETO26399.1 - 0.0029 16.7 1.4 0.58 9.2 0.0 3.2 1 1 3 4 4 4 1 Protein of unknown function (DUF1258) YqaJ PF09588.5 ETO26399.1 - 0.059 13.3 3.4 2.9 7.8 0.0 3.7 1 1 1 2 2 2 0 YqaJ-like viral recombinase domain USP7_C2 PF14533.1 ETO26399.1 - 0.15 11.4 2.8 32 3.8 0.0 3.9 1 1 2 3 3 3 0 Ubiquitin-specific protease C-terminal PD40 PF07676.7 ETO26399.1 - 0.43 10.2 11.1 3.2 7.5 0.1 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat zf-C3H1 PF10650.4 ETO26400.1 - 0.012 15.0 0.3 0.031 13.7 0.2 1.7 1 0 0 1 1 1 0 Putative zinc-finger domain ATP-synt_8 PF00895.15 ETO26400.1 - 1.6 8.9 3.9 0.88 9.8 0.8 2.0 2 0 0 2 2 2 0 ATP synthase protein 8 Ras PF00071.17 ETO26402.1 - 1.4e-06 27.8 0.1 0.036 13.4 0.0 2.4 2 0 0 2 2 2 2 Ras family Miro PF08477.8 ETO26402.1 - 0.018 15.5 0.1 1.2 9.5 0.1 2.9 1 1 0 1 1 1 0 Miro-like protein SirB PF04247.7 ETO26405.1 - 5.4 6.7 28.2 0.028 14.1 5.9 2.8 3 1 1 4 4 4 0 Invasion gene expression up-regulator, SirB ADP_ribosyl_GH PF03747.9 ETO26406.1 - 1.3e-15 57.9 0.0 2.6e-15 56.9 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylglycohydrolase NMD3 PF04981.8 ETO26407.1 - 2e-31 108.9 0.6 2.4e-31 108.7 0.4 1.1 1 0 0 1 1 1 1 NMD3 family zf-C3HC4_4 PF15227.1 ETO26407.1 - 0.024 14.5 3.3 2.2 8.2 0.0 3.3 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING DZR PF12773.2 ETO26407.1 - 0.079 12.7 0.9 0.079 12.7 0.6 2.1 1 1 1 2 2 2 0 Double zinc ribbon HypA PF01155.14 ETO26407.1 - 0.77 9.4 3.3 3.4 7.3 0.2 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF2946 PF11162.3 ETO26408.1 - 0.025 14.7 1.4 0.056 13.6 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) IncA PF04156.9 ETO26408.1 - 0.56 9.7 5.7 1.3 8.6 3.9 1.5 1 0 0 1 1 1 0 IncA protein HECT PF00632.20 ETO26409.1 - 3.3e-74 249.8 0.1 5.5e-74 249.1 0.1 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Fapy_DNA_glyco PF01149.19 ETO26410.1 - 5.1e-25 88.1 0.1 6.8e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 ETO26410.1 - 5.2e-16 58.1 0.4 1.4e-15 56.7 0.0 1.9 3 0 0 3 3 3 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.6 ETO26410.1 - 0.068 11.6 0.0 0.097 11.1 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) IGFL PF14653.1 ETO26410.1 - 1.8 8.6 8.1 5.1 7.1 0.0 3.0 3 0 0 3 3 3 0 Insulin growth factor-like family Adaptin_N PF01602.15 ETO26411.1 - 2.4e-25 88.8 0.4 3.4e-25 88.3 0.3 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Adaptin_N PF01602.15 ETO26412.1 - 1.2e-21 76.6 0.1 1.5e-21 76.3 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region DUF2201_N PF13203.1 ETO26412.1 - 0.6 9.2 4.0 0.81 8.8 2.8 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.9 ETO26412.1 - 2.6 5.9 5.7 2.9 5.8 3.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF778 PF05608.7 ETO26413.1 - 5.6 6.9 9.0 33 4.4 6.1 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF778) TPR_12 PF13424.1 ETO26414.1 - 1e-29 102.2 0.7 2.1e-16 59.6 0.2 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO26414.1 - 4.9e-17 61.3 19.3 8.8e-09 34.9 2.6 3.3 1 1 2 3 3 3 3 TPR repeat TPR_7 PF13176.1 ETO26414.1 - 3.4e-16 57.6 0.5 0.00012 21.6 0.1 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO26414.1 - 3.6e-15 55.3 0.0 5.7e-05 22.8 0.0 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO26414.1 - 3.5e-11 42.0 10.1 5.7e-06 25.7 0.8 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO26414.1 - 4.4e-11 41.9 14.0 1.8e-06 27.2 1.4 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO26414.1 - 4.3e-10 38.7 13.6 1.2e-05 24.8 0.5 4.7 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO26414.1 - 6e-06 26.3 4.0 0.34 11.4 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO26414.1 - 6.1e-06 26.0 3.0 0.0051 16.9 0.5 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat MIT PF04212.13 ETO26414.1 - 0.00021 21.0 7.2 0.2 11.5 0.4 4.0 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_14 PF13428.1 ETO26414.1 - 0.0013 19.1 0.2 7.8 7.4 0.0 4.1 5 0 0 5 5 3 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO26414.1 - 0.0016 18.5 5.8 0.063 13.4 1.5 3.7 2 2 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 ETO26414.1 - 0.0033 18.0 0.9 3 8.6 0.2 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO26414.1 - 0.021 15.1 0.8 0.23 11.8 0.0 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat HNF-1A_C PF04813.7 ETO26414.1 - 0.15 12.3 0.1 0.39 11.0 0.0 1.7 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus SAM_1 PF00536.25 ETO26416.1 - 2.1e-08 34.2 0.3 2.2e-07 30.9 0.1 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO26416.1 - 1.9e-05 24.4 0.1 4.6e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 ETO26416.1 - 0.00038 20.1 1.2 0.00093 18.9 0.8 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain OSTbeta PF15048.1 ETO26416.1 - 0.79 9.8 5.5 0.8 9.7 1.5 2.2 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein COX14 PF14880.1 ETO26416.1 - 4.4 7.0 6.1 0.82 9.3 0.3 2.3 2 0 0 2 2 2 0 Cytochrome oxidase c assembly MRP-L46 PF11788.3 ETO26416.1 - 5.2 7.7 12.5 0.72 10.5 4.0 2.6 2 1 1 3 3 3 0 39S mitochondrial ribosomal protein L46 Neur_chan_memb PF02932.11 ETO26416.1 - 10 5.9 6.9 3 7.6 1.5 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PH PF00169.24 ETO26417.1 - 1e-06 28.8 1.1 1.8e-06 28.1 0.7 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 ETO26417.1 - 0.0049 17.0 0.2 0.0093 16.2 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain AntA PF08346.7 ETO26417.1 - 0.0064 16.6 2.1 0.013 15.6 1.4 1.6 1 1 0 1 1 1 1 AntA/AntB antirepressor Lipase_3 PF01764.20 ETO26417.1 - 0.13 11.9 0.2 3.6 7.1 0.1 2.4 3 0 0 3 3 3 0 Lipase (class 3) Kelch_1 PF01344.20 ETO26418.1 - 0.0031 17.0 1.5 0.04 13.4 0.5 2.9 2 1 0 2 2 2 1 Kelch motif DUF4118 PF13493.1 ETO26418.1 - 0.034 14.3 2.3 0.055 13.6 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) Kelch_6 PF13964.1 ETO26418.1 - 0.061 13.5 1.7 0.38 11.0 0.2 2.8 2 1 1 3 3 3 0 Kelch motif Aha1_N PF09229.6 ETO26419.1 - 1.4e-07 31.3 0.3 1.4e-07 31.3 0.2 2.7 2 2 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal Peptidase_S64 PF08192.6 ETO26419.1 - 0.019 13.3 11.3 0.019 13.2 7.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 Mem_trans PF03547.13 ETO26419.1 - 0.029 12.6 3.3 0.038 12.3 2.3 1.2 1 0 0 1 1 1 0 Membrane transport protein MDFI PF15316.1 ETO26419.1 - 5.2 7.0 12.1 0.92 9.4 5.7 1.7 2 0 0 2 2 2 0 MyoD family inhibitor FPL PF09758.4 ETO26420.1 - 1.5e-32 112.4 14.6 2.9e-29 101.7 5.4 2.7 3 0 0 3 3 3 2 Uncharacterised conserved protein YTH PF04146.10 ETO26420.1 - 0.043 13.4 1.9 0.093 12.3 1.4 1.5 1 0 0 1 1 1 0 YT521-B-like domain Fun_ATP-synt_8 PF05933.8 ETO26420.1 - 4 7.5 9.5 1.8 8.6 0.4 2.9 2 0 0 2 2 2 0 Fungal ATP synthase protein 8 (A6L) Ank_2 PF12796.2 ETO26423.1 - 6.9e-97 317.9 23.9 3.5e-17 62.5 0.1 8.0 3 2 6 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 ETO26423.1 - 8.2e-71 230.5 18.4 6.2e-08 32.0 0.0 14.1 15 0 0 15 15 15 13 Ankyrin repeat Ank_4 PF13637.1 ETO26423.1 - 1.7e-62 206.7 12.1 6.5e-10 39.2 0.0 10.5 5 2 4 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO26423.1 - 3e-51 166.2 18.0 1.3e-05 24.9 0.0 14.0 14 0 0 14 14 14 11 Ankyrin repeat Ank_5 PF13857.1 ETO26423.1 - 5.8e-50 166.2 20.7 1.8e-09 37.4 0.1 11.7 6 4 6 12 12 12 11 Ankyrin repeats (many copies) CAP_GLY PF01302.20 ETO26423.1 - 3.6e-27 93.8 1.7 2.8e-17 62.1 0.2 2.5 2 0 0 2 2 2 2 CAP-Gly domain CDC45 PF02724.9 ETO26423.1 - 1.3 6.9 9.2 2.6 5.9 6.4 1.4 1 0 0 1 1 1 0 CDC45-like protein V_ATPase_I PF01496.14 ETO26424.1 - 0.13 10.1 3.2 0.15 9.8 2.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RNA_pol_Rpc82 PF05645.8 ETO26424.1 - 0.13 11.7 8.7 0.17 11.4 6.0 1.1 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 DUF4519 PF15012.1 ETO26424.1 - 0.52 10.2 20.0 0.16 11.8 2.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Neur_chan_memb PF02932.11 ETO26424.1 - 0.74 9.6 4.9 0.78 9.5 3.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF106 PF01956.11 ETO26424.1 - 2.6 7.5 7.0 4.6 6.7 4.9 1.5 1 1 0 1 1 1 0 Integral membrane protein DUF106 PPR_2 PF13041.1 ETO26425.1 - 9.4e-14 51.1 2.8 6.5e-06 26.0 0.1 3.0 2 0 0 2 2 2 2 PPR repeat family PPR PF01535.15 ETO26425.1 - 3.1e-10 39.3 6.6 0.033 14.1 0.2 4.8 4 0 0 4 4 4 4 PPR repeat PPR_3 PF13812.1 ETO26425.1 - 1.2e-07 31.4 0.1 0.33 11.3 0.0 4.8 4 0 0 4 4 4 3 Pentatricopeptide repeat domain ATP13 PF12921.2 ETO26425.1 - 0.014 14.7 1.7 0.32 10.3 0.0 2.8 2 1 1 3 3 3 0 Mitochondrial ATPase expression Mnd1 PF03962.10 ETO26426.1 - 2.1e-06 27.5 0.7 2.6e-06 27.2 0.0 1.5 2 0 0 2 2 2 1 Mnd1 family Dev_Cell_Death PF10539.4 ETO26426.1 - 0.071 12.6 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 Development and cell death domain WD40 PF00400.27 ETO26427.1 - 4.2e-79 257.8 7.1 1e-14 53.7 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO26427.1 - 4.7e-11 41.5 5.1 0.12 10.5 0.2 5.7 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO26427.1 - 3.2e-09 36.0 10.7 0.043 12.5 1.1 5.8 1 1 4 5 5 5 5 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO26427.1 - 1.8e-08 33.1 0.8 0.00035 19.0 0.0 3.6 1 1 2 4 4 4 4 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO26427.1 - 2.3e-06 27.2 1.0 0.00012 21.6 0.5 3.2 1 1 1 2 2 2 1 PQQ-like domain DPPIV_N PF00930.16 ETO26427.1 - 0.0003 19.4 0.3 0.16 10.5 0.0 3.3 1 1 2 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.7 ETO26427.1 - 0.0022 17.6 10.0 3.5 7.4 0.0 5.9 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO26427.1 - 0.0028 17.8 0.1 21 5.4 0.0 4.3 2 2 3 5 5 5 0 Resistin Methyltransf_16 PF10294.4 ETO26429.1 - 1.5e-18 66.8 0.0 2.3e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 ETO26429.1 - 0.081 13.5 0.1 0.15 12.6 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 ETO26429.1 - 0.089 12.3 0.1 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain EpoR_lig-bind PF09067.5 ETO26430.1 - 0.031 14.2 1.3 0.13 12.2 0.2 1.9 1 1 1 2 2 2 0 Erythropoietin receptor, ligand binding ATG27 PF09451.5 ETO26430.1 - 0.049 12.8 0.3 0.058 12.6 0.2 1.0 1 0 0 1 1 1 0 Autophagy-related protein 27 WD40 PF00400.27 ETO26431.1 - 2.4e-33 112.7 11.2 5e-11 42.0 0.1 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat Cerato-platanin PF07249.7 ETO26431.1 - 0.0017 18.3 0.8 0.0029 17.5 0.1 1.7 2 0 0 2 2 2 1 Cerato-platanin Nup160 PF11715.3 ETO26431.1 - 0.0027 15.9 1.1 0.042 11.9 0.8 2.0 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Barttin PF15462.1 ETO26431.1 - 0.12 12.0 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Aa_trans PF01490.13 ETO26432.1 - 5.3e-13 48.2 3.0 7e-13 47.8 1.1 1.8 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein FA_desaturase PF00487.19 ETO26432.1 - 5.5 6.3 10.1 8.7 5.7 0.8 3.9 2 1 1 4 4 4 0 Fatty acid desaturase MSC PF09402.5 ETO26432.1 - 7.8 5.1 6.5 1.7 7.2 0.0 2.7 3 0 0 3 3 3 0 Man1-Src1p-C-terminal domain AA_permease PF00324.16 ETO26433.1 - 1.5e-19 69.7 15.3 1.9e-19 69.4 10.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETO26433.1 - 0.054 12.0 13.1 0.074 11.5 9.1 1.2 1 0 0 1 1 1 0 Amino acid permease AA_permease PF00324.16 ETO26434.1 - 1.9e-18 66.1 20.4 4.4e-17 61.5 8.7 2.0 2 0 0 2 2 2 2 Amino acid permease POX PF07526.6 ETO26437.1 - 0.016 15.4 3.7 0.018 15.2 2.6 1.0 1 0 0 1 1 1 0 Associated with HOX DUF3384 PF11864.3 ETO26437.1 - 0.056 11.9 6.3 0.057 11.8 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) Methyltransf_12 PF08242.7 ETO26437.1 - 0.093 13.2 3.7 0.13 12.7 2.6 1.3 1 1 0 1 1 1 0 Methyltransferase domain Ctr PF04145.10 ETO26437.1 - 0.15 12.1 1.9 0.16 12.0 1.3 1.0 1 0 0 1 1 1 0 Ctr copper transporter family Apis_Csd PF11671.3 ETO26437.1 - 0.16 11.7 11.1 0.16 11.7 7.7 1.1 1 0 0 1 1 1 0 Complementary sex determiner protein GSG-1 PF07803.6 ETO26437.1 - 0.17 11.4 1.2 0.18 11.4 0.8 1.0 1 0 0 1 1 1 0 GSG1-like protein PMSI1 PF15322.1 ETO26437.1 - 0.24 10.4 3.2 0.28 10.2 2.2 1.0 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative DUF4094 PF13334.1 ETO26437.1 - 0.85 10.0 5.9 1 9.7 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Folliculin PF11704.3 ETO26437.1 - 1 8.9 4.9 0.93 9.0 3.4 1.0 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport ATS PF15445.1 ETO26437.1 - 1.2 8.1 11.7 1.2 8.1 8.1 1.0 1 0 0 1 1 1 0 acidic terminal segments, variant surface antigen of PfEMP1 PH_4 PF15404.1 ETO26437.1 - 1.2 8.5 7.2 1.2 8.6 5.0 1.0 1 0 0 1 1 1 0 Pleckstrin homology domain APC_CDC26 PF10471.4 ETO26437.1 - 4.3 8.1 7.6 5.5 7.7 5.3 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Microtub_bind PF13931.1 ETO26437.1 - 5.2 7.2 9.2 5.2 7.2 6.4 1.0 1 0 0 1 1 1 0 Kinesin-associated microtubule-binding Pkinase PF00069.20 ETO26438.1 - 2.5e-55 187.4 0.8 1.5e-49 168.5 0.1 2.8 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO26438.1 - 6.8e-26 90.8 0.2 3.4e-25 88.5 0.2 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase CDC45 PF02724.9 ETO26438.1 - 5.2e-05 21.4 17.0 8.2e-05 20.8 11.8 1.3 1 0 0 1 1 1 1 CDC45-like protein APH PF01636.18 ETO26438.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family SAPS PF04499.10 ETO26438.1 - 0.048 12.2 11.9 0.081 11.5 8.3 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mem_trans PF03547.13 ETO26438.1 - 0.17 10.1 0.2 0.22 9.7 0.2 1.3 1 0 0 1 1 1 0 Membrane transport protein CENP-T PF15511.1 ETO26438.1 - 0.21 10.7 20.7 0.3 10.2 14.4 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T SprA-related PF12118.3 ETO26438.1 - 3.6 6.8 28.1 5.9 6.1 19.4 1.3 1 0 0 1 1 1 0 SprA-related family Daxx PF03344.10 ETO26438.1 - 4.1 5.7 40.0 6.5 5.0 27.7 1.2 1 0 0 1 1 1 0 Daxx Family G-alpha PF00503.15 ETO26439.1 - 3.8e-47 160.8 7.1 4.5e-47 160.5 4.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO26439.1 - 1.2e-08 34.3 0.6 2.9e-08 33.1 0.4 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETO26439.1 - 9.7e-06 24.8 2.5 1.2e-05 24.5 1.7 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region HNOB PF07700.10 ETO26439.1 - 0.043 13.3 1.1 0.052 13.0 0.6 1.3 1 1 0 1 1 1 0 Heme NO binding GTP_EFTU PF00009.22 ETO26439.1 - 0.05 13.0 0.2 0.06 12.7 0.1 1.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Sep15_SelM PF08806.6 ETO26440.1 - 2.4e-10 40.0 3.2 7.9e-10 38.3 0.3 2.6 2 1 0 2 2 2 1 Sep15/SelM redox domain Ank PF00023.25 ETO26441.1 - 0.044 13.6 0.0 0.082 12.7 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeat Hrs_helical PF12210.3 ETO26441.1 - 0.046 13.9 0.2 0.076 13.2 0.2 1.4 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Oxidored_q1_N PF00662.15 ETO26442.1 - 0.14 11.6 7.5 0.23 11.0 0.2 3.1 2 1 1 3 3 3 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Pox_A14 PF05767.7 ETO26442.1 - 0.3 11.0 0.1 0.3 11.0 0.1 2.7 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 ABG_transport PF03806.8 ETO26442.1 - 3.8 5.4 7.7 0.65 7.9 2.9 1.4 2 0 0 2 2 2 0 AbgT putative transporter family RNA_pol_Rpc4 PF05132.9 ETO26443.1 - 0.015 15.3 0.2 0.029 14.3 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 ResB PF05140.9 ETO26443.1 - 0.036 12.6 0.1 0.036 12.6 0.1 1.1 1 0 0 1 1 1 0 ResB-like family UPF0139 PF03669.8 ETO26444.1 - 0.033 13.7 0.6 0.12 11.9 0.2 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) WBS_methylT PF12589.3 ETO26445.1 - 0.54 10.7 11.8 1.3 9.5 8.1 1.6 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome Sec62 PF03839.11 ETO26445.1 - 0.99 8.7 7.5 0.51 9.7 2.1 2.3 2 0 0 2 2 2 0 Translocation protein Sec62 Nop14 PF04147.7 ETO26446.1 - 0.033 12.1 31.8 0.045 11.6 22.0 1.2 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 ETO26446.1 - 0.5 8.7 35.6 0.66 8.4 24.7 1.1 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 ETO26446.1 - 1.9 7.6 32.4 3.1 7.0 22.5 1.3 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.8 ETO26446.1 - 7.8 4.1 27.2 11 3.6 18.9 1.4 1 0 0 1 1 1 0 DNA polymerase phi PH_3 PF14593.1 ETO26447.1 - 1.1e-08 34.9 0.1 3.5e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 PH domain DUF946 PF06101.6 ETO26447.1 - 4.1e-07 28.3 0.0 6.4e-07 27.7 0.0 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) PH_11 PF15413.1 ETO26447.1 - 0.00041 20.5 0.3 0.0034 17.6 0.2 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain Myosin_TH1 PF06017.8 ETO26447.1 - 0.00062 19.1 0.0 0.0016 17.7 0.0 1.7 1 0 0 1 1 1 1 Myosin tail ODV-E18 PF10717.4 ETO26447.1 - 0.24 10.8 0.5 0.62 9.5 0.3 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 HECT PF00632.20 ETO26449.1 - 2.6e-88 296.2 0.6 2.6e-88 296.2 0.4 2.3 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) BUD22 PF09073.5 ETO26449.1 - 0.0039 16.3 17.5 0.0039 16.3 12.1 2.4 3 0 0 3 3 3 1 BUD22 RR_TM4-6 PF06459.7 ETO26449.1 - 0.42 10.4 26.4 1.2 8.9 6.2 2.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.3 ETO26449.1 - 0.56 8.7 20.1 0.11 11.0 2.8 2.5 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.9 ETO26449.1 - 4 5.3 22.8 0.73 7.8 0.7 2.3 2 0 0 2 2 2 0 CDC45-like protein Zip PF02535.17 ETO26449.1 - 9.8 5.0 7.2 4.4 6.2 0.3 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter 2OG-FeII_Oxy_3 PF13640.1 ETO26451.1 - 0.0026 18.2 0.1 0.048 14.1 0.0 2.8 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily TPK_catalytic PF04263.11 ETO26452.1 - 6.1e-18 64.5 0.0 9.8e-18 63.9 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 ETO26452.1 - 6.1e-16 57.8 0.1 1.2e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Transferase PF02458.10 ETO26454.1 - 0.0029 16.1 0.0 0.006 15.0 0.0 1.5 1 1 0 1 1 1 1 Transferase family BSP_II PF05432.6 ETO26455.1 - 0.13 11.4 19.2 0.13 11.4 13.3 1.0 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) FAM176 PF14851.1 ETO26455.1 - 2.8 7.6 8.7 3.3 7.3 6.0 1.3 1 0 0 1 1 1 0 FAM176 family DUF3381 PF11861.3 ETO26455.1 - 3.2 7.2 10.8 3 7.3 7.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Spb1_C PF07780.7 ETO26455.1 - 3.5 7.0 6.8 3.4 7.0 4.7 1.0 1 0 0 1 1 1 0 Spb1 C-terminal domain Prothymosin PF03247.9 ETO26455.1 - 3.6 7.7 28.0 3.9 7.6 19.4 1.1 1 0 0 1 1 1 0 Prothymosin/parathymosin family CobT PF06213.7 ETO26455.1 - 5.2 6.1 17.3 4.8 6.2 12.0 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sigma70_ner PF04546.8 ETO26455.1 - 5.3 6.6 15.0 5.6 6.5 10.4 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF1510 PF07423.6 ETO26455.1 - 7.4 5.8 11.2 7.4 5.8 7.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Upf2 PF04050.9 ETO26455.1 - 7.5 6.2 15.9 7.5 6.2 11.0 1.0 1 0 0 1 1 1 0 Up-frameshift suppressor 2 Daxx PF03344.10 ETO26455.1 - 8.6 4.6 20.7 8.5 4.7 14.3 1.0 1 0 0 1 1 1 0 Daxx Family Rhodanese PF00581.15 ETO26456.1 - 4.1e-05 23.8 0.0 0.0001 22.6 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain DUF4551 PF15087.1 ETO26456.1 - 0.3 9.3 7.8 0.4 8.9 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Mito_fiss_reg PF05308.6 ETO26456.1 - 0.91 8.8 7.2 1.4 8.2 5.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF3446 PF11928.3 ETO26456.1 - 9.9 6.4 10.7 3.9 7.7 4.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3446) DUF4304 PF14137.1 ETO26459.1 - 0.019 15.0 0.9 0.083 13.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4304) Patatin PF01734.17 ETO26460.1 - 2e-06 27.8 0.0 2.2e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Patatin-like phospholipase GARS_A PF01071.14 ETO26461.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain zf-CCCH_2 PF14608.1 ETO26463.1 - 0.0036 17.2 1.0 0.021 14.7 0.7 2.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type Zip PF02535.17 ETO26463.1 - 0.0045 16.0 12.9 0.0088 15.0 9.0 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter zf-CCCH PF00642.19 ETO26463.1 - 0.69 9.6 8.6 0.13 11.9 0.3 2.8 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Met_gamma_lyase PF06838.6 ETO26465.1 - 0.012 13.8 0.3 0.018 13.3 0.2 1.3 1 0 0 1 1 1 0 Methionine gamma-lyase DUF1013 PF06242.6 ETO26465.1 - 0.092 12.7 0.6 0.2 11.6 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1013) LepA_C PF06421.7 ETO26465.1 - 0.4 10.6 5.2 5.6 6.9 0.0 3.0 3 0 0 3 3 3 0 GTP-binding protein LepA C-terminus DMPK_coil PF08826.5 ETO26465.1 - 2.3 8.2 7.3 10 6.1 3.3 2.4 2 0 0 2 2 2 0 DMPK coiled coil domain like MscS_TM PF12794.2 ETO26466.1 - 0.02 13.4 1.5 0.029 12.9 1.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF975 PF06161.6 ETO26466.1 - 0.023 14.4 0.5 0.038 13.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF975) ETRAMP PF09716.5 ETO26466.1 - 0.13 12.2 13.8 0.21 11.5 1.4 3.6 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) HAUS6_N PF14661.1 ETO26467.1 - 0.011 15.0 0.3 0.014 14.7 0.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus MCR_alpha PF02249.12 ETO26468.1 - 0.027 14.4 0.2 0.13 12.2 0.0 2.2 1 1 1 2 2 2 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain WD40 PF00400.27 ETO26469.1 - 1.1e-12 47.2 8.4 0.12 12.3 0.1 7.9 9 0 0 9 9 9 4 WD domain, G-beta repeat P12 PF12669.2 ETO26469.1 - 0.22 11.7 3.1 14 5.9 0.3 3.1 2 0 0 2 2 2 0 Virus attachment protein p12 family PRT_C PF08372.5 ETO26469.1 - 2.9 7.3 4.3 0.95 8.9 0.7 1.8 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal RasGEF PF00617.14 ETO26470.1 - 0.00026 20.7 0.0 0.00048 19.8 0.0 1.4 2 0 0 2 2 2 1 RasGEF domain Sigma70_ECF PF07638.6 ETO26470.1 - 0.0071 16.0 0.0 0.0077 15.9 0.0 1.1 1 0 0 1 1 1 1 ECF sigma factor UBA_e1_C PF09358.5 ETO26470.1 - 0.17 12.0 1.8 0.27 11.4 1.2 1.4 1 0 0 1 1 1 0 Ubiquitin-activating enzyme e1 C-terminal domain RasGEF PF00617.14 ETO26471.1 - 8.5e-21 74.5 0.1 2.1e-20 73.2 0.1 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 ETO26471.1 - 3.3e-14 52.8 0.3 1e-13 51.2 0.2 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif CENP-H PF05837.7 ETO26472.1 - 0.13 12.4 5.3 0.34 11.1 3.7 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) IncA PF04156.9 ETO26472.1 - 1.1 8.8 6.8 2.1 7.9 4.7 1.4 1 0 0 1 1 1 0 IncA protein Prefoldin PF02996.12 ETO26472.1 - 7.1 6.3 9.5 4.1 7.0 1.1 2.4 2 0 0 2 2 2 0 Prefoldin subunit VWA_2 PF13519.1 ETO26473.1 - 1.1e-09 38.6 0.0 1.8e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 ETO26473.1 - 3.5e-05 23.6 0.0 6.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Helicase_C PF00271.26 ETO26473.1 - 0.065 13.0 0.1 0.27 11.1 0.1 2.0 1 1 0 1 1 1 0 Helicase conserved C-terminal domain EMP24_GP25L PF01105.19 ETO26474.1 - 0.092 12.4 9.5 0.17 11.5 2.0 2.9 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD zf-Sec23_Sec24 PF04810.10 ETO26475.1 - 1.6e-05 24.3 2.2 0.00043 19.7 0.3 2.4 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger SART-1 PF03343.8 ETO26475.1 - 0.078 11.3 2.8 0.32 9.2 1.9 1.7 1 1 0 1 1 1 0 SART-1 family Ank PF00023.25 ETO26476.1 - 2.7e-10 39.5 0.4 0.0005 19.7 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 ETO26476.1 - 3.9e-10 39.9 0.0 8.1e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO26476.1 - 3.3e-09 36.0 0.1 0.0031 17.6 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 ETO26476.1 - 3.7e-09 36.5 0.2 0.00039 20.5 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO26476.1 - 2.6e-07 30.9 0.4 0.0032 17.9 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 ETO26477.1 - 2.4e-05 23.9 0.0 8e-05 22.2 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat HEAT_2 PF13646.1 ETO26477.1 - 0.00025 21.2 0.1 0.3 11.3 0.1 3.8 2 1 0 2 2 2 1 HEAT repeats Ank_3 PF13606.1 ETO26477.1 - 0.00065 19.6 0.1 0.007 16.5 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat DUF3718 PF12514.3 ETO26477.1 - 0.0022 17.9 0.1 0.0073 16.3 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3718) Ank_5 PF13857.1 ETO26477.1 - 0.0032 17.6 0.1 0.015 15.5 0.1 2.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) SGS PF05002.10 ETO26477.1 - 0.011 15.4 1.0 4.1 7.2 0.2 2.9 2 0 0 2 2 2 0 SGS domain Ank_4 PF13637.1 ETO26477.1 - 0.026 15.0 0.4 0.13 12.7 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) RNA_binding PF01877.12 ETO26477.1 - 0.2 11.6 1.5 5.3 7.0 0.1 3.5 2 2 0 2 2 2 0 RNA binding Cas_Cmr5 PF09701.5 ETO26477.1 - 0.35 11.0 3.4 5 7.3 0.1 3.1 2 1 0 2 2 2 0 CRISPR-associated protein (Cas_Cmr5) HEAT PF02985.17 ETO26477.1 - 0.79 9.9 2.7 1.9e+02 2.5 0.0 4.8 4 0 0 4 4 4 0 HEAT repeat HEAT PF02985.17 ETO26478.1 - 1.4e-05 24.7 0.1 0.19 11.8 0.0 4.1 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 ETO26478.1 - 0.001 19.2 0.0 0.073 13.3 0.0 2.7 2 1 0 2 2 2 1 HEAT repeats Vac14_Fab1_bd PF12755.2 ETO26478.1 - 0.088 13.1 3.7 0.21 11.9 0.3 3.0 1 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 ETO26478.1 - 0.093 13.2 0.0 20 5.8 0.0 3.4 3 1 0 3 3 3 0 HEAT-like repeat PhnA_Zn_Ribbon PF08274.7 ETO26478.1 - 0.15 11.8 0.3 0.38 10.5 0.2 1.6 1 0 0 1 1 1 0 PhnA Zinc-Ribbon Xin PF08043.7 ETO26479.1 - 0.14 11.9 0.1 0.44 10.3 0.1 1.9 1 0 0 1 1 1 0 Xin repeat DUF605 PF04652.11 ETO26480.1 - 0.0063 15.9 12.5 0.0074 15.7 8.6 1.2 1 0 0 1 1 1 1 Vta1 like Arm PF00514.18 ETO26481.1 - 1.5e-05 24.6 16.5 0.0053 16.5 0.2 7.5 7 2 0 8 8 8 3 Armadillo/beta-catenin-like repeat Ric8 PF10165.4 ETO26481.1 - 0.0033 16.3 0.5 0.042 12.6 0.1 2.6 2 1 0 2 2 2 1 Guanine nucleotide exchange factor synembryn Atx10homo_assoc PF09759.4 ETO26481.1 - 0.0058 16.3 10.5 0.39 10.4 0.5 5.2 4 1 1 5 5 5 1 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.8 ETO26481.1 - 0.0068 15.5 5.1 0.63 9.1 0.1 3.9 3 1 1 4 4 4 2 Armadillo-like Mcp5_PH PF12814.2 ETO26481.1 - 0.0093 15.8 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology GntP_permease PF02447.11 ETO26481.1 - 0.042 12.3 0.0 0.081 11.3 0.0 1.4 1 0 0 1 1 1 0 GntP family permease PH PF00169.24 ETO26481.1 - 0.049 13.8 0.3 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 PH domain HEAT PF02985.17 ETO26481.1 - 0.11 12.5 3.0 1.7 8.9 0.2 4.2 4 0 0 4 4 4 0 HEAT repeat Amb_V_allergen PF03913.8 ETO26483.1 - 0.028 14.1 0.1 0.028 14.1 0.1 1.9 2 0 0 2 2 2 0 Amb V Allergen Cyclin PF08613.6 ETO26484.1 - 0.00019 21.8 2.0 0.00031 21.1 0.4 2.0 1 1 1 2 2 2 1 Cyclin DUF1027 PF06265.6 ETO26484.1 - 0.032 14.1 0.0 0.078 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) Spuma_A9PTase PF03539.9 ETO26484.1 - 0.075 12.9 0.2 0.075 12.9 0.1 1.8 2 0 0 2 2 2 0 Spumavirus aspartic protease (A9) RRM_1 PF00076.17 ETO26485.1 - 1.7e-11 43.5 0.3 1.6e-10 40.4 0.0 2.3 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO26485.1 - 0.00011 22.1 0.0 0.00074 19.4 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO26485.1 - 0.00074 19.3 0.6 0.033 14.0 0.1 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 ETO26485.1 - 0.016 15.0 0.1 0.028 14.2 0.0 1.6 1 1 0 1 1 1 0 RNA binding motif DUF4042 PF13251.1 ETO26487.1 - 3.9e-10 39.4 0.8 9.8e-08 31.6 0.1 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4042) Ipi1_N PF12333.3 ETO26487.1 - 0.00062 19.6 0.0 0.31 11.0 0.0 2.8 2 0 0 2 2 2 2 Rix1 complex component involved in 60S ribosome maturation HEAT PF02985.17 ETO26487.1 - 0.019 14.9 0.8 1.7 8.9 0.0 2.9 2 1 0 2 2 2 0 HEAT repeat DUF4470 PF14737.1 ETO26487.1 - 0.062 13.0 0.0 0.43 10.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4470) RIX1 PF08167.7 ETO26488.1 - 0.05 13.2 0.8 0.54 9.9 0.0 2.2 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis EPSP_synthase PF00275.15 ETO26489.1 - 0.0049 15.3 0.0 0.011 14.2 0.0 1.5 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) BTB PF00651.26 ETO26490.1 - 1.2e-21 76.7 4.8 1.9e-13 50.3 1.1 4.1 3 1 0 3 3 3 2 BTB/POZ domain DUF2457 PF10446.4 ETO26490.1 - 0.027 13.2 8.6 0.038 12.7 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sigma70_ner PF04546.8 ETO26490.1 - 0.033 13.8 5.6 0.059 12.9 3.9 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region CobT PF06213.7 ETO26490.1 - 0.16 11.0 8.4 0.23 10.5 5.5 1.4 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT PBP1_TM PF14812.1 ETO26490.1 - 1 9.7 11.0 2 8.8 7.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.7 ETO26490.1 - 1.7 7.8 7.3 3.2 6.9 5.1 1.3 1 0 0 1 1 1 0 NOA36 protein TMEM154 PF15102.1 ETO26491.1 - 0.005 16.5 0.5 0.016 14.9 0.4 1.9 1 0 0 1 1 1 1 TMEM154 protein family zf-LITAF-like PF10601.4 ETO26491.1 - 0.015 15.1 0.1 0.026 14.3 0.1 1.4 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain DUF4448 PF14610.1 ETO26491.1 - 0.016 14.6 0.8 0.035 13.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Herpes_gE PF02480.11 ETO26491.1 - 0.052 11.8 0.1 0.084 11.1 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Shisa PF13908.1 ETO26491.1 - 1.1 9.3 4.0 0.3 11.2 0.3 1.9 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator BRCT PF00533.21 ETO26492.1 - 6.5e-06 26.1 1.0 0.00014 21.9 0.2 2.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Spore_coat_CotO PF14153.1 ETO26492.1 - 0.0048 16.3 9.9 0.01 15.2 6.8 1.4 1 0 0 1 1 1 1 Spore coat protein CotO PTCB-BRCT PF12738.2 ETO26492.1 - 0.009 15.8 0.1 0.099 12.5 0.1 2.6 2 0 0 2 2 2 1 twin BRCT domain DUF2722 PF10846.3 ETO26492.1 - 0.087 11.8 12.5 0.15 11.0 8.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Radial_spoke PF04712.7 ETO26492.1 - 0.12 11.1 8.9 0.2 10.3 6.2 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein DUF2890 PF11081.3 ETO26492.1 - 0.18 11.8 12.6 0.31 11.0 8.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF1980 PF09323.5 ETO26492.1 - 0.76 9.4 7.9 1.7 8.3 5.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Trypan_PARP PF05887.6 ETO26492.1 - 1 9.1 7.0 1.8 8.4 4.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CDC45 PF02724.9 ETO26492.1 - 3.3 5.6 11.5 4.7 5.1 8.0 1.3 1 0 0 1 1 1 0 CDC45-like protein PT PF04886.7 ETO26493.1 - 7.5e-09 34.7 47.5 0.00015 21.0 14.2 2.9 1 1 1 2 2 2 2 PT repeat Sporozoite_P67 PF05642.6 ETO26495.1 - 0.049 11.5 1.6 0.045 11.6 1.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Synaphin PF05835.7 ETO26495.1 - 0.12 12.4 1.6 0.14 12.2 1.1 1.1 1 0 0 1 1 1 0 Synaphin protein DUF2118 PF09891.4 ETO26495.1 - 0.15 11.7 1.4 0.19 11.4 1.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) Ribosomal_S20p PF01649.13 ETO26495.1 - 0.23 11.8 3.9 0.31 11.4 2.7 1.3 1 1 0 1 1 1 0 Ribosomal protein S20 DUF3452 PF11934.3 ETO26495.1 - 0.33 10.2 3.5 0.37 10.1 2.4 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) NAC PF01849.13 ETO26497.1 - 3.5e-13 48.8 3.5 6.7e-07 28.7 0.0 2.4 2 0 0 2 2 2 2 NAC domain Avl9 PF09794.4 ETO26497.1 - 0.029 12.8 1.4 0.064 11.7 1.0 1.5 1 0 0 1 1 1 0 Transport protein Avl9 Ribosomal_L30 PF00327.15 ETO26497.1 - 0.3 10.7 2.6 3.8 7.1 1.1 2.7 2 0 0 2 2 2 0 Ribosomal protein L30p/L7e Ndc1_Nup PF09531.5 ETO26497.1 - 0.66 8.3 7.2 0.87 7.9 5.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.8 ETO26497.1 - 1.9 8.2 18.2 2.7 7.8 12.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.3 ETO26497.1 - 5 6.2 23.0 0.04 13.1 10.1 1.7 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal MCPVI PF02993.9 ETO26497.1 - 9 6.3 12.9 14 5.7 8.9 1.2 1 0 0 1 1 1 0 Minor capsid protein VI UBA PF00627.26 ETO26498.1 - 6.1e-05 22.7 0.5 0.00012 21.8 0.3 1.5 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 ETO26498.1 - 0.027 14.0 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain UvrB PF12344.3 ETO26499.1 - 0.0024 17.3 0.2 0.0054 16.2 0.1 1.5 1 0 0 1 1 1 1 Ultra-violet resistance protein B Phospho_p8 PF10195.4 ETO26500.1 - 0.016 15.0 0.1 0.034 14.0 0.1 1.6 1 0 0 1 1 1 0 DNA-binding nuclear phosphoprotein p8 Trs65 PF12735.2 ETO26501.1 - 0.29 10.3 0.0 0.29 10.3 0.0 4.0 4 0 0 4 4 4 0 TRAPP trafficking subunit Trs65 Imm35 PF15581.1 ETO26502.1 - 0.0066 16.4 0.4 1.7 8.7 0.0 2.2 1 1 1 2 2 2 2 Immunity protein 35 Kinesin PF00225.18 ETO26502.1 - 0.057 12.1 0.2 0.068 11.8 0.2 1.1 1 0 0 1 1 1 0 Kinesin motor domain Kinesin PF00225.18 ETO26503.1 - 3.8e-28 98.1 0.1 4.2e-28 98.0 0.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain BpuSI_N PF15516.1 ETO26503.1 - 0.087 12.5 0.2 0.22 11.2 0.0 1.6 2 0 0 2 2 2 0 BpuSI N-terminal domain ubiquitin PF00240.18 ETO26504.1 - 4.2e-09 35.6 0.1 4.2e-09 35.6 0.1 2.8 3 0 0 3 3 3 1 Ubiquitin family Rad60-SLD PF11976.3 ETO26504.1 - 1.1e-07 31.3 0.1 4e-07 29.6 0.1 2.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like EF-hand_5 PF13202.1 ETO26504.1 - 0.00027 20.1 0.1 0.00099 18.3 0.1 2.0 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 ETO26504.1 - 0.0012 18.5 0.0 0.0066 16.2 0.0 2.3 1 0 0 1 1 1 1 EF-hand domain DUF912 PF06024.7 ETO26504.1 - 0.0064 16.5 0.1 0.0064 16.5 0.1 2.4 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) EF-hand_1 PF00036.27 ETO26504.1 - 0.0065 15.6 0.1 0.032 13.5 0.1 2.3 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 ETO26504.1 - 0.041 14.0 0.1 0.19 11.8 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain pair SlyX PF04102.7 ETO26504.1 - 2.8 8.3 12.2 0.96 9.8 0.8 3.6 2 1 1 3 3 3 0 SlyX zf-AN1 PF01428.11 ETO26505.1 - 0.00017 21.3 6.5 0.00036 20.3 4.5 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger Ank_5 PF13857.1 ETO26506.1 - 4.4e-06 26.7 0.0 1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO26506.1 - 2e-05 24.8 0.0 9e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO26506.1 - 8e-05 22.2 0.0 0.013 15.2 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 ETO26506.1 - 0.023 14.9 0.0 4.1 7.9 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeat Ank_4 PF13637.1 ETO26506.1 - 0.042 14.3 0.0 1.5 9.3 0.0 2.9 2 1 1 3 3 3 0 Ankyrin repeats (many copies) NPV_P10 PF05531.7 ETO26507.1 - 0.11 12.7 14.6 1.2 9.4 1.0 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF2911 PF11138.3 ETO26507.1 - 1.3 8.6 9.3 0.39 10.3 3.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2911) Baculo_PEP_C PF04513.7 ETO26507.1 - 4.4 7.1 12.5 0.028 14.2 1.1 2.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus PUB PF09409.5 ETO26509.1 - 0.098 12.4 7.5 0.038 13.7 1.1 3.2 2 1 0 2 2 2 0 PUB domain PepSY_TM_2 PF13703.1 ETO26512.1 - 0.089 12.9 1.9 0.12 12.5 1.3 1.3 1 1 0 1 1 1 0 PepSY-associated TM helix CHIPS PF11434.3 ETO26512.1 - 0.11 12.1 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Chemotaxis-inhibiting protein CHIPS CAP_GLY PF01302.20 ETO26513.1 - 1.2e-13 50.5 2.6 2e-13 49.8 1.8 1.3 1 0 0 1 1 1 1 CAP-Gly domain HAS-barrel PF09378.5 ETO26513.1 - 0.029 14.2 1.0 0.048 13.5 0.7 1.5 1 1 0 1 1 1 0 HAS barrel domain MUG113 PF13455.1 ETO26513.1 - 0.098 13.1 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 Meiotically up-regulated gene 113 2OG-FeII_Oxy_3 PF13640.1 ETO26514.1 - 1.3e-07 32.0 0.2 2.8e-07 30.9 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.8 ETO26515.1 - 0.0044 17.0 2.5 0.0081 16.2 0.0 2.4 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) Herpes_UL55 PF04537.7 ETO26515.1 - 0.031 13.6 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL55 protein Rubredoxin PF00301.15 ETO26515.1 - 0.21 11.4 4.9 5.6 6.9 3.4 3.0 1 1 0 1 1 1 0 Rubredoxin SID-1_RNA_chan PF13965.1 ETO26515.1 - 0.66 8.0 4.8 0.31 9.1 0.8 1.9 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 DUF4407 PF14362.1 ETO26515.1 - 2.8 6.8 6.4 0.13 11.2 0.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4448 PF14610.1 ETO26516.1 - 0.047 13.1 0.1 0.087 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF4064 PF13273.1 ETO26516.1 - 0.055 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) S-AdoMet_synt_M PF02772.11 ETO26517.1 - 0.2 11.5 2.8 0.43 10.5 1.9 1.5 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, central domain TFIIF_alpha PF05793.7 ETO26518.1 - 0.0012 17.3 30.2 0.0012 17.3 20.9 2.1 2 0 0 2 2 2 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MIP-T3 PF10243.4 ETO26518.1 - 0.34 9.3 48.3 0.91 7.9 16.2 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 DUF1777 PF08648.7 ETO26518.1 - 0.39 10.4 62.0 0.2 11.3 5.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1777) INT_SG_DDX_CT_C PF15300.1 ETO26519.1 - 0.017 14.5 2.1 0.053 12.9 0.0 2.7 3 0 0 3 3 3 0 INTS6/SAGE1/DDX26B/CT45 C-terminus EcsB PF05975.7 ETO26523.1 - 0.25 9.7 4.3 0.049 12.0 0.2 1.7 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB Mannosyl_trans3 PF11051.3 ETO26524.1 - 1.6e-06 27.6 0.0 2.2e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Lyase_1 PF00206.15 ETO26525.1 - 8e-09 35.1 0.0 9.7e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 Lyase MaoC_dehydrat_N PF13452.1 ETO26525.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase Ras PF00071.17 ETO26526.1 - 7.1e-30 103.5 1.4 5.2e-14 51.9 0.2 2.6 2 1 0 2 2 2 2 Ras family Miro PF08477.8 ETO26526.1 - 1.1e-14 54.9 0.0 2.4e-12 47.4 0.0 2.5 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO26526.1 - 9.8e-09 34.6 0.5 0.00083 18.6 0.0 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETO26526.1 - 4.2e-07 29.3 0.3 0.0017 17.5 0.0 2.1 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 ETO26526.1 - 5e-06 26.0 0.4 0.0032 16.9 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Chordopox_E11 PF06138.7 ETO26526.1 - 0.024 14.7 0.2 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Chordopoxvirus E11 protein Myosin_tail_1 PF01576.14 ETO26527.1 - 0.0037 15.0 68.8 0.0054 14.5 47.7 1.2 1 0 0 1 1 1 1 Myosin tail bZIP_1 PF00170.16 ETO26527.1 - 0.022 14.7 1.1 0.022 14.7 0.8 7.9 5 2 2 7 7 7 0 bZIP transcription factor Reo_sigmaC PF04582.7 ETO26527.1 - 0.32 10.1 21.4 1.2 8.2 2.4 3.1 1 1 3 4 4 4 0 Reovirus sigma C capsid protein PH PF00169.24 ETO26529.1 - 4.5e-13 49.3 0.1 4.5e-13 49.3 0.1 2.3 2 1 0 2 2 2 1 PH domain PH_6 PF15406.1 ETO26529.1 - 5.6e-05 23.1 1.0 0.00012 22.1 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.1 ETO26529.1 - 0.00028 21.1 2.4 0.00037 20.7 0.2 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain Mcp5_PH PF12814.2 ETO26529.1 - 0.00045 20.1 0.8 0.00045 20.1 0.6 2.5 3 1 1 4 4 4 1 Meiotic cell cortex C-terminal pleckstrin homology PH_4 PF15404.1 ETO26529.1 - 0.035 13.6 0.1 0.035 13.6 0.1 3.1 2 1 0 2 2 2 0 Pleckstrin homology domain PH_9 PF15410.1 ETO26529.1 - 0.6 10.2 4.3 0.31 11.2 0.1 2.5 2 1 0 2 2 2 0 Pleckstrin homology domain C2 PF00168.25 ETO26530.1 - 9.4e-09 35.0 0.0 8.7e-08 31.9 0.0 2.1 1 1 0 1 1 1 1 C2 domain Cation_ATPase_C PF00689.16 ETO26530.1 - 0.051 13.1 0.3 0.13 11.7 0.1 1.6 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus WD40 PF00400.27 ETO26531.1 - 2.4e-56 185.7 18.8 1.4e-11 43.8 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO26531.1 - 1.2e-09 36.9 6.0 0.16 10.0 0.0 5.2 1 1 4 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO26531.1 - 0.013 14.2 14.7 0.023 13.4 0.5 4.4 2 2 2 4 4 4 0 Nup133 N terminal like FYVE PF01363.16 ETO26531.1 - 2.7 7.9 9.5 1.7 8.5 3.2 2.6 2 0 0 2 2 2 0 FYVE zinc finger FeThRed_B PF02943.10 ETO26533.1 - 0.0064 16.1 0.8 0.0064 16.1 0.5 1.9 2 0 0 2 2 2 1 Ferredoxin thioredoxin reductase catalytic beta chain Presenilin PF01080.12 ETO26533.1 - 0.18 10.5 1.2 0.25 10.1 0.9 1.2 1 0 0 1 1 1 0 Presenilin Mucin PF01456.12 ETO26534.1 - 9.6 5.9 32.0 0.99 9.1 19.0 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein WD40 PF00400.27 ETO26535.1 - 7.1e-19 66.9 0.1 1.6e-08 34.0 0.1 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat WD40 PF00400.27 ETO26536.1 - 6e-12 44.9 0.4 2.4e-11 43.0 0.1 1.9 2 0 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO26536.1 - 0.022 12.9 0.0 0.022 12.9 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DUF4512 PF14975.1 ETO26538.1 - 0.68 10.7 0.1 0.68 10.7 0.1 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4512) Methyltransf_23 PF13489.1 ETO26539.1 - 1.1e-11 44.7 0.0 2.1e-11 43.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO26539.1 - 2.9e-08 34.0 0.1 1.4e-07 31.9 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO26539.1 - 2.1e-07 30.6 0.1 7.5e-07 28.8 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO26539.1 - 1.4e-06 28.8 0.0 6e-06 26.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETO26539.1 - 4e-06 27.2 0.0 1.1e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 ETO26539.1 - 2e-05 23.7 0.0 5.3e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 ETO26539.1 - 0.00022 21.5 0.0 0.00071 19.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Mit_ribos_Mrp51 PF11709.3 ETO26540.1 - 0.1 11.8 2.4 0.15 11.2 1.7 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit DUF506 PF04720.7 ETO26540.1 - 0.73 9.4 3.9 1.4 8.4 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF506) SNF2_N PF00176.18 ETO26541.1 - 9e-34 116.6 0.0 1.9e-33 115.5 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETO26541.1 - 1.9e-11 43.6 0.0 4.3e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 ETO26541.1 - 0.0088 14.8 0.1 0.0088 14.8 0.1 3.0 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 ETO26541.1 - 0.055 13.2 3.9 0.33 10.7 0.0 3.0 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit PCI_Csn8 PF10075.4 ETO26544.1 - 5.9e-27 94.2 0.6 8.5e-27 93.6 0.4 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 ETO26544.1 - 0.00017 21.2 0.2 0.00023 20.7 0.1 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family UPF0154 PF03672.8 ETO26545.1 - 0.0059 16.1 0.1 0.012 15.1 0.1 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0154) NfeD PF01957.13 ETO26545.1 - 0.007 16.5 2.8 0.071 13.2 0.0 2.6 2 2 0 2 2 2 1 NfeD-like C-terminal, partner-binding DUF340 PF03956.8 ETO26545.1 - 0.062 12.5 7.1 0.064 12.5 1.5 2.7 3 0 0 3 3 3 0 Membrane protein of unknown function (DUF340) YajC PF02699.10 ETO26545.1 - 1.4 8.6 5.0 0.41 10.3 0.3 2.4 3 0 0 3 3 3 0 Preprotein translocase subunit DUF3329 PF11808.3 ETO26545.1 - 4.4 7.4 6.5 3.7 7.6 0.1 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF3329) Vpu PF00558.14 ETO26545.1 - 7.2 6.2 5.9 1.2 8.7 0.2 2.6 3 1 0 3 3 3 0 Vpu protein Tim54 PF11711.3 ETO26548.1 - 0.24 9.9 1.7 0.49 8.9 0.0 1.9 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 WD40 PF00400.27 ETO26549.1 - 1.4e-15 56.4 2.7 3e-08 33.2 0.3 4.4 3 1 1 4 4 4 3 WD domain, G-beta repeat PD40 PF07676.7 ETO26549.1 - 0.0017 17.9 0.6 1.1 9.0 0.0 4.1 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat DUF4347 PF14252.1 ETO26549.1 - 0.075 12.5 0.2 0.17 11.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4347) P4Ha_N PF08336.6 ETO26549.1 - 0.23 11.2 1.8 0.34 10.7 0.3 1.8 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region RRM_1 PF00076.17 ETO26550.1 - 9.4e-29 98.8 0.6 5.4e-21 73.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 ETO26550.1 - 2e-28 97.8 1.0 4.1e-28 96.8 0.7 1.6 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_6 PF14259.1 ETO26550.1 - 1.6e-24 85.6 0.1 4.3e-15 55.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO26550.1 - 2.5e-15 56.0 0.4 5.4e-10 38.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2414 PF10309.4 ETO26550.1 - 0.15 11.7 0.5 50 3.6 0.0 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF2414) ATP-grasp_4 PF13535.1 ETO26551.1 - 2.2e-06 27.5 0.0 3.3e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain PBP_sp32 PF07222.7 ETO26551.1 - 9.3 5.3 12.3 1.8 7.6 3.7 2.3 2 0 0 2 2 2 0 Proacrosin binding protein sp32 PUF PF00806.14 ETO26552.1 - 9.2e-16 56.3 0.4 0.0002 20.6 0.0 4.1 4 0 0 4 4 4 3 Pumilio-family RNA binding repeat RasGEF PF00617.14 ETO26553.1 - 2.7e-11 43.5 0.0 4e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 RasGEF domain RasGEF PF00617.14 ETO26554.1 - 1.7e-18 67.0 0.4 1.9e-18 66.8 0.2 1.0 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 ETO26555.1 - 0.0018 18.3 0.1 0.004 17.2 0.0 1.6 2 0 0 2 2 2 1 RasGEF N-terminal motif DUF445 PF04286.7 ETO26555.1 - 0.0035 16.9 0.5 0.0044 16.6 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF445) DUF4415 PF14384.1 ETO26555.1 - 0.42 10.8 2.0 0.62 10.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4415) TMCO5 PF14992.1 ETO26555.1 - 0.67 9.0 6.0 0.082 12.0 0.3 1.9 2 0 0 2 2 2 0 TMCO5 family Proteasome PF00227.21 ETO26556.1 - 2.7e-16 59.4 0.1 5.3e-16 58.4 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit Proteasome PF00227.21 ETO26557.1 - 6.9e-22 77.6 0.1 8.7e-22 77.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Guanylate_kin PF00625.16 ETO26558.1 - 6.6e-45 152.8 0.2 3.6e-44 150.3 0.1 1.8 1 1 0 1 1 1 1 Guanylate kinase DUF258 PF03193.11 ETO26558.1 - 0.0014 17.8 0.0 0.0028 16.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 ETO26558.1 - 0.0025 18.6 0.1 0.0058 17.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ETO26558.1 - 0.007 16.5 0.2 0.0095 16.0 0.2 1.7 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 ETO26558.1 - 0.0095 15.8 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 ETO26558.1 - 0.034 14.1 0.0 0.18 11.7 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 ETO26558.1 - 0.071 12.9 0.0 0.17 11.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain ATP-synt_B PF00430.13 ETO26558.1 - 0.075 12.8 0.4 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) RNA_helicase PF00910.17 ETO26558.1 - 0.11 12.7 0.1 0.35 11.0 0.0 1.8 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.22 ETO26558.1 - 0.11 12.8 0.1 0.26 11.5 0.0 1.8 2 1 0 2 2 2 0 ABC transporter Miro PF08477.8 ETO26558.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein Isy1 PF06246.7 ETO26559.1 - 1.5e-65 221.1 15.3 6e-65 219.1 10.6 1.8 1 1 0 1 1 1 1 Isy1-like splicing family ATG16 PF08614.6 ETO26559.1 - 0.24 11.1 9.2 0.43 10.3 1.4 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DAO PF01266.19 ETO26560.1 - 8e-36 123.6 0.0 9.3e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETO26560.1 - 2.1e-05 23.5 0.5 0.0015 17.4 0.4 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 ETO26560.1 - 0.00015 21.0 1.0 0.00035 19.7 0.5 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 ETO26560.1 - 0.0088 15.9 0.2 0.018 14.9 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETO26560.1 - 0.049 13.6 0.8 0.13 12.3 0.5 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 ETO26560.1 - 0.054 11.9 0.4 0.078 11.4 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 ETO26560.1 - 0.07 13.1 0.3 0.12 12.4 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETO26560.1 - 0.15 12.5 1.0 0.94 9.9 0.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETO26560.1 - 0.18 10.6 0.2 0.26 10.1 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 ETO26560.1 - 0.22 10.3 0.3 2 7.1 0.2 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 ETO26560.1 - 0.27 10.8 1.2 0.86 9.2 0.9 1.8 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain BUD22 PF09073.5 ETO26562.1 - 0.002 17.2 8.8 0.002 17.2 6.1 5.4 4 1 1 5 5 5 2 BUD22 Nop25 PF09805.4 ETO26562.1 - 0.0026 17.8 8.5 0.0026 17.8 5.9 6.2 7 1 0 7 7 7 1 Nucleolar protein 12 (25kDa) SSP160 PF06933.6 ETO26562.1 - 0.12 10.3 16.0 0.18 9.7 11.1 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 YhhN PF07947.9 ETO26562.1 - 0.33 10.2 0.3 0.56 9.5 0.2 1.2 1 0 0 1 1 1 0 YhhN-like protein DUF3439 PF11921.3 ETO26562.1 - 4.8 6.9 16.8 14 5.5 11.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) ATG16 PF08614.6 ETO26563.1 - 8.4e-05 22.4 0.9 8.4e-05 22.4 0.6 2.5 1 1 0 2 2 2 1 Autophagy protein 16 (ATG16) FH2 PF02181.18 ETO26563.1 - 0.0028 16.5 2.2 0.0028 16.5 1.5 2.4 2 1 1 3 3 3 1 Formin Homology 2 Domain V-SNARE_C PF12352.3 ETO26563.1 - 0.053 13.5 0.4 1 9.4 0.1 2.6 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus IpaC_SipC PF09599.5 ETO26563.1 - 0.17 10.8 3.2 0.25 10.3 0.2 2.0 2 0 0 2 2 2 0 Salmonella-Shigella invasin protein C (IpaC_SipC) SPARC_Ca_bdg PF10591.4 ETO26563.1 - 0.28 11.2 6.0 0.44 10.5 2.2 2.4 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Imm5 PF14423.1 ETO26563.1 - 0.46 10.0 3.0 1.1 8.8 1.8 1.7 1 1 1 2 2 2 0 Immunity protein Imm5 CENP-Q PF13094.1 ETO26563.1 - 0.54 10.2 11.4 0.1 12.6 3.1 2.3 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DivIC PF04977.10 ETO26563.1 - 0.63 9.5 9.4 0.32 10.5 0.1 3.3 3 1 0 3 3 3 0 Septum formation initiator COG5 PF10392.4 ETO26563.1 - 0.77 9.7 10.3 0.53 10.2 0.1 3.2 2 1 0 3 3 3 0 Golgi transport complex subunit 5 Atg14 PF10186.4 ETO26563.1 - 1.2 8.0 12.6 1.5 7.7 3.6 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 YlqD PF11068.3 ETO26563.1 - 1.2 9.1 13.2 1.6 8.7 2.2 2.9 2 1 1 3 3 3 0 YlqD protein Fib_alpha PF08702.5 ETO26563.1 - 1.4 9.0 16.9 0.44 10.6 1.6 3.2 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family BRCA-2_OB3 PF09104.5 ETO26564.1 - 0.0022 17.8 0.2 0.0026 17.6 0.2 1.2 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 Pox_VP8_L4R PF04498.7 ETO26564.1 - 0.013 14.8 0.4 0.015 14.6 0.3 1.2 1 0 0 1 1 1 0 Poxvirus nucleic acid binding protein VP8/L4R MCR_C PF04609.7 ETO26564.1 - 0.088 11.5 0.1 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C SCIMP PF15050.1 ETO26567.1 - 3.5e-05 23.7 0.5 5.3e-05 23.1 0.3 1.2 1 0 0 1 1 1 1 SCIMP protein DAG1 PF05454.6 ETO26567.1 - 0.0039 16.4 0.0 0.0066 15.6 0.0 1.3 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) ERAP1_C PF11838.3 ETO26567.1 - 0.0082 15.4 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain ATG27 PF09451.5 ETO26567.1 - 0.022 13.9 0.3 0.03 13.5 0.2 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 WBP-1 PF11669.3 ETO26567.1 - 0.026 14.6 0.0 0.045 13.8 0.0 1.3 1 0 0 1 1 1 0 WW domain-binding protein 1 DUF3619 PF12279.3 ETO26567.1 - 0.068 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) TMEM52 PF14979.1 ETO26567.1 - 0.082 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Transmembrane 52 Tetraspannin PF00335.15 ETO26567.1 - 0.097 11.9 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Tetraspanin family ATP-synt_E PF05680.7 ETO26567.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 ATP synthase E chain ResB PF05140.9 ETO26567.1 - 0.4 9.1 2.1 0.69 8.3 1.5 1.3 1 0 0 1 1 1 0 ResB-like family PhyH PF05721.8 ETO26568.1 - 6.6e-10 39.3 0.6 1.2e-06 28.7 0.1 2.9 2 1 1 3 3 3 2 Phytanoyl-CoA dioxygenase (PhyH) HD_4 PF13328.1 ETO26569.1 - 0.053 13.2 0.1 0.096 12.3 0.1 1.3 1 0 0 1 1 1 0 HD domain A_deaminase PF00962.17 ETO26571.1 - 2.7e-19 69.2 0.0 6.3e-19 68.0 0.0 1.6 1 1 0 1 1 1 1 Adenosine/AMP deaminase Hist_deacetyl PF00850.14 ETO26572.1 - 1.3e-65 221.7 1.9 7.1e-46 156.9 0.0 2.5 3 0 0 3 3 3 2 Histone deacetylase domain DUF1256 PF06866.6 ETO26572.1 - 0.062 12.4 1.1 0.13 11.4 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1256) Peptidase_M4 PF01447.13 ETO26572.1 - 0.39 10.8 2.2 0.34 11.0 0.1 1.9 2 0 0 2 2 2 0 Thermolysin metallopeptidase, catalytic domain Mg_trans_NIPA PF05653.9 ETO26574.1 - 1.2e-06 27.7 0.1 1.8e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA RRM_1 PF00076.17 ETO26575.1 - 1.8e-09 37.0 0.3 3.8e-09 36.0 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO26575.1 - 2e-09 37.2 0.1 3.9e-09 36.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO26575.1 - 0.0002 21.1 0.2 0.00052 19.8 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kinesin PF00225.18 ETO26576.1 - 9.7e-46 155.9 0.1 1.2e-45 155.6 0.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain DUF2118 PF09891.4 ETO26576.1 - 0.0096 15.6 0.0 0.063 12.9 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2118) AAA_10 PF12846.2 ETO26576.1 - 0.1 11.9 0.1 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain ABC2_membrane_3 PF12698.2 ETO26577.1 - 0.074 12.0 4.8 4.1 6.3 0.0 2.5 2 0 0 2 2 2 0 ABC-2 family transporter protein PRA1 PF03208.14 ETO26578.1 - 0.037 13.3 0.5 0.052 12.8 0.3 1.2 1 0 0 1 1 1 0 PRA1 family protein F-box-like PF12937.2 ETO26580.1 - 0.00012 21.7 0.0 0.00027 20.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like Cnd1_N PF12922.2 ETO26580.1 - 0.26 10.9 4.0 0.26 10.8 0.1 2.7 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1, N-term MIP-T3 PF10243.4 ETO26581.1 - 4.4e-07 28.7 16.6 5.4e-07 28.4 11.5 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Mitofilin PF09731.4 ETO26581.1 - 0.0001 21.1 6.6 0.00012 20.8 4.6 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein BUD22 PF09073.5 ETO26581.1 - 1 8.3 39.6 1.6 7.6 27.4 1.3 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.9 ETO26581.1 - 3 5.7 26.9 5.1 4.9 18.7 1.4 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 ETO26581.1 - 6.2 4.4 18.8 7.6 4.1 13.0 1.1 1 0 0 1 1 1 0 Ycf1 DUF3456 PF11938.3 ETO26582.1 - 0.022 14.7 5.0 0.029 14.3 3.4 1.3 1 0 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP Secretin_N_2 PF07655.8 ETO26582.1 - 0.023 15.0 13.7 0.037 14.4 9.5 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain Corona_nucleoca PF00937.13 ETO26582.1 - 0.041 12.8 4.1 0.043 12.7 2.9 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein CytochromB561_N PF09786.4 ETO26582.1 - 0.059 11.8 6.2 0.061 11.7 4.3 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF506 PF04720.7 ETO26582.1 - 0.17 11.5 9.0 0.19 11.3 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF506) POX PF07526.6 ETO26582.1 - 0.2 11.8 5.2 0.25 11.5 3.6 1.2 1 0 0 1 1 1 0 Associated with HOX FAM60A PF15396.1 ETO26582.1 - 0.26 11.0 5.5 0.28 10.9 3.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Pex16 PF08610.5 ETO26582.1 - 0.32 9.9 3.2 0.35 9.8 2.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) FAM75 PF14650.1 ETO26582.1 - 1 8.6 10.6 1.3 8.3 7.4 1.1 1 0 0 1 1 1 0 FAM75 family DUF3385 PF11865.3 ETO26582.1 - 1.3 8.9 5.3 1.5 8.7 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) Presenilin PF01080.12 ETO26582.1 - 2.4 6.8 4.9 2.4 6.8 3.4 1.1 1 0 0 1 1 1 0 Presenilin Mgr1 PF08602.5 ETO26582.1 - 7.2 5.5 8.6 8.7 5.2 5.9 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit HDA2-3 PF11496.3 ETO26583.1 - 1.1e-08 34.2 0.3 7.5e-06 24.9 0.0 2.3 2 1 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 SNF2_N PF00176.18 ETO26583.1 - 1.4e-05 24.0 0.2 2.1e-05 23.5 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Med19 PF10278.4 ETO26584.1 - 0.52 9.9 15.3 1.3 8.6 2.1 2.4 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 ERp29 PF07749.7 ETO26584.1 - 0.9 10.2 6.5 0.39 11.3 0.6 2.6 2 1 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain vMSA PF00695.14 ETO26584.1 - 1.4 8.0 5.6 0.39 9.8 1.0 1.7 1 1 1 2 2 2 0 Major surface antigen from hepadnavirus Daxx PF03344.10 ETO26584.1 - 1.4 7.3 21.0 1.7 7.0 14.5 1.1 1 0 0 1 1 1 0 Daxx Family SR-25 PF10500.4 ETO26584.1 - 4.1 6.8 41.0 1.9 7.8 18.8 2.2 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein EF-hand_7 PF13499.1 ETO26585.1 - 0.0025 17.9 0.1 0.012 15.7 0.1 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO26585.1 - 0.02 14.1 1.7 0.11 11.8 0.0 3.0 4 0 0 4 4 4 0 EF hand EF-hand_6 PF13405.1 ETO26585.1 - 0.028 14.2 0.0 0.19 11.6 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain TauE PF01925.14 ETO26586.1 - 0.016 14.7 1.5 0.02 14.3 1.0 1.3 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE DUF997 PF06196.7 ETO26586.1 - 0.018 14.5 3.1 0.025 14.1 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF997) ART PF01129.13 ETO26587.1 - 0.0007 18.7 0.3 0.0016 17.5 0.0 1.7 2 0 0 2 2 2 1 NAD:arginine ADP-ribosyltransferase HSBP1 PF06825.7 ETO26588.1 - 0.023 14.2 0.3 0.34 10.5 0.1 2.5 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Ubiq_cyt_C_chap PF03981.7 ETO26588.1 - 0.046 13.5 0.1 0.081 12.7 0.1 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone Kelch_5 PF13854.1 ETO26589.1 - 1.7e-07 31.0 2.8 0.19 11.6 0.7 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 ETO26589.1 - 3.5e-07 29.6 1.9 0.0045 16.5 0.1 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO26589.1 - 3.3e-06 26.7 0.6 0.001 18.7 0.0 3.9 3 1 1 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO26589.1 - 3.6e-05 23.7 3.4 0.042 14.0 0.2 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO26589.1 - 0.00016 21.2 7.4 0.03 14.1 0.1 4.2 5 0 0 5 5 5 2 Kelch motif Peptidase_C14 PF00656.17 ETO26590.1 - 3.1e-12 46.7 0.4 6.6e-12 45.6 0.3 1.5 1 0 0 1 1 1 1 Caspase domain UCH PF00443.24 ETO26590.1 - 9.4 5.2 8.4 16 4.5 5.8 1.6 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase ABC_tran PF00005.22 ETO26592.1 - 4.2e-21 75.6 0.0 5.4e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 ETO26592.1 - 3.2e-06 27.3 0.0 0.0037 17.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 ETO26592.1 - 0.0073 16.2 0.5 0.042 13.7 0.1 2.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit CBS PF00571.23 ETO26592.1 - 0.064 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 CBS domain SMC_N PF02463.14 ETO26592.1 - 0.084 12.0 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain EF-hand_1 PF00036.27 ETO26593.1 - 0.0014 17.7 0.1 0.0031 16.6 0.0 1.6 1 0 0 1 1 1 1 EF hand CLASP_N PF12348.3 ETO26593.1 - 0.014 14.7 0.1 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 CLASP N terminal EF-hand_7 PF13499.1 ETO26593.1 - 0.028 14.5 0.1 0.079 13.1 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain pair Cullin_Nedd8 PF10557.4 ETO26593.1 - 0.096 12.5 0.1 0.29 10.9 0.0 1.8 1 0 0 1 1 1 0 Cullin protein neddylation domain Polyoma_lg_T_C PF06431.6 ETO26593.1 - 1.8 7.1 4.5 0.57 8.7 1.2 1.6 2 0 0 2 2 2 0 Polyomavirus large T antigen C-terminus XAP5 PF04921.9 ETO26593.1 - 6.4 6.2 19.3 7.7 6.0 2.9 2.3 2 0 0 2 2 2 0 XAP5, circadian clock regulator CLASP_N PF12348.3 ETO26594.1 - 3.6e-11 42.8 0.8 4.9e-11 42.4 0.5 1.2 1 0 0 1 1 1 1 CLASP N terminal EF-hand_7 PF13499.1 ETO26594.1 - 9.4e-07 28.8 0.3 2e-06 27.8 0.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO26594.1 - 9.1e-05 22.0 2.5 0.21 11.5 0.7 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 ETO26594.1 - 0.00028 19.9 6.0 0.16 11.3 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 ETO26594.1 - 0.0039 16.7 2.0 0.005 16.4 0.3 2.1 2 0 0 2 2 2 1 EF-hand domain pair A2M PF00207.17 ETO26594.1 - 0.032 13.7 0.0 0.065 12.8 0.0 1.5 1 0 0 1 1 1 0 Alpha-2-macroglobulin family p25-alpha PF05517.7 ETO26594.1 - 0.14 12.4 0.7 13 5.9 0.0 2.4 1 1 1 2 2 2 0 p25-alpha Dapper PF15268.1 ETO26595.1 - 0.0039 16.0 0.4 0.0047 15.8 0.3 1.1 1 0 0 1 1 1 1 Dapper E1_dh PF00676.15 ETO26597.1 - 2.9e-64 216.6 0.1 3.5e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.16 ETO26597.1 - 5.4e-07 28.7 0.1 7.6e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.1 ETO26597.1 - 0.0001 21.3 0.0 0.0008 18.4 0.0 2.0 1 1 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 ETO26597.1 - 0.0016 18.0 0.1 0.0051 16.4 0.1 1.7 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF4109 PF13397.1 ETO26597.1 - 0.011 16.1 0.4 5.5 7.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4109) Ribosomal_L6e PF01159.14 ETO26598.1 - 8.9e-28 96.6 2.5 1.6e-27 95.8 1.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L6e IL33 PF15095.1 ETO26598.1 - 0.0078 15.6 1.2 0.012 15.0 0.8 1.2 1 0 0 1 1 1 1 Interleukin 33 OAD_gamma PF04277.8 ETO26598.1 - 0.48 10.8 3.9 1 9.7 2.7 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain YL1 PF05764.8 ETO26600.1 - 0.0017 17.9 26.7 0.003 17.1 18.5 1.5 1 0 0 1 1 1 1 YL1 nuclear protein Nop53 PF07767.6 ETO26600.1 - 0.0032 16.5 30.7 0.0046 15.9 21.3 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.9 ETO26600.1 - 0.031 12.3 22.9 0.042 11.9 15.9 1.1 1 0 0 1 1 1 0 CDC45-like protein CinA PF02464.12 ETO26600.1 - 0.042 13.2 2.6 0.08 12.3 1.8 1.5 1 0 0 1 1 1 0 Competence-damaged protein Mucin PF01456.12 ETO26600.1 - 0.48 10.1 29.8 0.93 9.2 20.7 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein CT47 PF15623.1 ETO26600.1 - 0.54 9.9 16.3 0.7 9.5 11.3 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 DUF1510 PF07423.6 ETO26600.1 - 0.97 8.7 25.4 0.13 11.6 14.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) CAF-1_p150 PF11600.3 ETO26600.1 - 1.2 8.4 44.8 0.012 15.0 24.3 2.0 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CENP-T PF15511.1 ETO26600.1 - 1.3 8.2 19.0 0.86 8.7 12.4 1.3 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T RNA_polI_A34 PF08208.6 ETO26600.1 - 2 8.0 43.3 0.15 11.7 25.4 2.4 2 1 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 U79_P34 PF03064.11 ETO26600.1 - 8.5 5.8 27.1 15 4.9 18.7 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 SR-25 PF10500.4 ETO26601.1 - 0.035 13.5 11.4 0.044 13.2 7.9 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BSP_II PF05432.6 ETO26601.1 - 0.087 12.0 18.1 0.12 11.6 12.5 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CytochromB561_N PF09786.4 ETO26601.1 - 0.62 8.4 9.2 0.71 8.2 6.4 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal Mucin PF01456.12 ETO26601.1 - 0.65 9.7 11.1 0.87 9.3 7.7 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Presenilin PF01080.12 ETO26601.1 - 1.6 7.4 11.9 1.8 7.2 8.3 1.0 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.4 ETO26601.1 - 8.7 4.4 13.0 9.5 4.3 9.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Vps51 PF08700.6 ETO26602.1 - 0.021 14.6 0.1 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Vps51/Vps67 TFIIA PF03153.8 ETO26603.1 - 0.0032 17.4 31.8 0.0043 16.9 22.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit MIP-T3 PF10243.4 ETO26603.1 - 0.11 10.9 55.2 0.16 10.4 38.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Myosin_head PF00063.16 ETO26604.1 - 8.2e-16 57.2 0.0 1.3e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Kei1 PF08552.6 ETO26604.1 - 0.016 14.8 0.1 0.023 14.3 0.1 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Ion_trans PF00520.26 ETO26605.1 - 3.5e-11 42.7 33.4 6.9e-10 38.5 17.8 2.6 2 1 0 2 2 2 2 Ion transport protein PKD_channel PF08016.7 ETO26605.1 - 0.002 16.6 1.9 0.002 16.6 1.3 3.3 3 1 0 3 3 3 1 Polycystin cation channel UPF0233 PF06781.7 ETO26605.1 - 0.036 13.6 2.4 0.044 13.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) Tetraspannin PF00335.15 ETO26605.1 - 0.64 9.2 19.2 1.6 7.9 0.8 3.3 3 0 0 3 3 3 0 Tetraspanin family DUF912 PF06024.7 ETO26605.1 - 1.4 8.9 0.0 1.4 8.9 0.0 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2208 PF09973.4 ETO26605.1 - 8.2 5.5 17.4 0.14 11.3 0.1 3.3 3 0 0 3 3 3 0 Predicted membrane protein (DUF2208) zf-RING_2 PF13639.1 ETO26606.1 - 1.2e-05 25.0 0.8 2.8e-05 23.8 0.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 ETO26606.1 - 0.0014 18.7 1.6 0.0029 17.6 1.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger PHD PF00628.24 ETO26606.1 - 0.0034 17.0 1.4 0.0073 15.9 1.0 1.5 1 0 0 1 1 1 1 PHD-finger zf-RING_5 PF14634.1 ETO26606.1 - 0.0038 16.9 0.5 0.0079 15.8 0.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 ETO26606.1 - 0.0058 16.6 0.7 0.017 15.1 0.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO26606.1 - 0.011 15.3 3.1 0.028 14.0 2.1 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Spore_YpjB PF09577.5 ETO26606.1 - 0.041 13.4 0.2 0.063 12.8 0.1 1.2 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) zf-C3HC4_3 PF13920.1 ETO26606.1 - 0.074 12.7 0.3 0.17 11.6 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) GrpE PF01025.14 ETO26606.1 - 0.14 11.7 0.9 0.29 10.6 0.6 1.5 1 1 0 1 1 1 0 GrpE TAXi_N PF14543.1 ETO26607.1 - 0.043 13.7 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal PQQ PF01011.16 ETO26607.1 - 0.12 11.9 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat Daxx PF03344.10 ETO26608.1 - 0.00024 19.7 15.1 0.00024 19.7 10.5 2.1 2 0 0 2 2 2 2 Daxx Family Secretin_N_2 PF07655.8 ETO26609.1 - 6.4 7.2 17.8 21 5.6 12.3 1.8 1 0 0 1 1 1 0 Secretin N-terminal domain Rft-1 PF04506.8 ETO26610.1 - 7.1e-42 143.4 7.1 8.4e-42 143.2 4.9 1.1 1 0 0 1 1 1 1 Rft protein DUF912 PF06024.7 ETO26610.1 - 0.18 11.8 1.1 1.1 9.3 0.0 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2663 PF10864.3 ETO26610.1 - 2.1 8.5 9.0 0.48 10.6 0.9 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2663) DUF4293 PF14126.1 ETO26610.1 - 4.4 7.2 7.7 4.2 7.2 0.0 3.7 3 2 2 5 5 5 0 Domain of unknown function (DUF4293) Fe-S_biosyn PF01521.15 ETO26611.1 - 9.1e-15 54.5 0.7 1.5e-14 53.8 0.1 1.7 2 0 0 2 2 2 1 Iron-sulphur cluster biosynthesis UBN2_3 PF14244.1 ETO26612.1 - 0.09 12.3 0.4 0.095 12.2 0.3 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type FA_synthesis PF02504.10 ETO26612.1 - 0.12 11.1 0.1 0.13 11.0 0.0 1.0 1 0 0 1 1 1 0 Fatty acid synthesis protein Pkinase PF00069.20 ETO26614.1 - 1.7e-05 24.1 0.0 4.1e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO26614.1 - 0.00021 20.4 0.0 0.00055 19.0 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase G-alpha PF00503.15 ETO26615.1 - 1.9e-18 66.3 1.0 2.2e-18 66.1 0.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO26615.1 - 0.031 13.5 0.2 0.048 12.9 0.1 1.3 1 1 0 1 1 1 0 ADP-ribosylation factor family SRPRB PF09439.5 ETO26615.1 - 0.045 12.9 0.0 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 ETO26615.1 - 0.14 11.6 0.4 0.2 11.1 0.3 1.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DSPc PF00782.15 ETO26616.1 - 1e-26 93.0 0.3 1.2e-26 92.8 0.2 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 ETO26616.1 - 3.4e-06 26.5 0.1 4.1e-06 26.3 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 ETO26616.1 - 0.0023 18.0 0.0 0.0041 17.1 0.0 1.4 1 1 0 1 1 1 1 Inositol hexakisphosphate Init_tRNA_PT PF04179.7 ETO26616.1 - 0.0056 15.6 0.2 0.0058 15.5 0.1 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase2 PF03162.8 ETO26616.1 - 0.037 13.3 0.5 0.058 12.7 0.3 1.6 1 1 0 1 1 1 0 Tyrosine phosphatase family GPCR_chapero_1 PF11904.3 ETO26617.1 - 0.18 10.9 8.9 0.19 10.8 6.2 1.1 1 0 0 1 1 1 0 GPCR-chaperone DUF2217 PF10265.4 ETO26617.1 - 0.27 9.9 2.3 0.33 9.6 1.6 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Macoilin PF09726.4 ETO26617.1 - 0.69 8.1 8.0 0.7 8.1 5.5 1.0 1 0 0 1 1 1 0 Transmembrane protein Pox_Ag35 PF03286.9 ETO26617.1 - 0.71 9.3 8.4 0.92 8.9 5.8 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Band_3_cyto PF07565.8 ETO26617.1 - 0.78 9.2 3.0 0.88 9.0 2.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Neur_chan_memb PF02932.11 ETO26617.1 - 1 9.1 5.9 1.2 8.9 4.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GCD14 PF08704.5 ETO26617.1 - 2.6 7.4 5.4 3.5 7.0 3.7 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit POX PF07526.6 ETO26617.1 - 3.2 7.9 5.5 5.1 7.3 3.8 1.4 1 0 0 1 1 1 0 Associated with HOX RP-C_C PF11800.3 ETO26617.1 - 4.9 6.7 6.9 5.7 6.5 4.8 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Glyco_hydro_47 PF01532.15 ETO26618.1 - 2.5e-41 141.7 0.1 3.4e-41 141.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Nic96 PF04097.9 ETO26619.1 - 0.00034 18.8 0.1 0.0004 18.6 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 BTV_NS2 PF04514.7 ETO26620.1 - 6.2 5.5 14.1 7.8 5.2 9.8 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Nic96 PF04097.9 ETO26621.1 - 3.1e-29 101.6 5.3 2.6e-14 52.3 0.1 3.0 3 0 0 3 3 3 3 Nup93/Nic96 MS_channel PF00924.13 ETO26621.1 - 0.05 12.9 0.0 0.088 12.1 0.0 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel Nic96 PF04097.9 ETO26622.1 - 2.9e-05 22.4 0.0 3.2e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Nup93/Nic96 DUF3439 PF11921.3 ETO26622.1 - 0.012 15.3 1.7 0.023 14.4 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 ETO26622.1 - 0.084 10.8 3.0 0.11 10.4 2.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3435 PF11917.3 ETO26623.1 - 0.19 10.4 2.8 0.25 10.0 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) FAM219A PF15260.1 ETO26623.1 - 0.19 12.0 7.4 0.048 14.0 2.3 1.9 1 1 1 2 2 2 0 Protein family FAM219A Mucin PF01456.12 ETO26623.1 - 0.97 9.2 12.7 1.5 8.5 8.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.7 ETO26623.1 - 1.1 6.9 11.9 1.2 6.7 8.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Podoplanin PF05808.6 ETO26623.1 - 1.2 8.7 7.4 1.5 8.3 5.1 1.3 1 0 0 1 1 1 0 Podoplanin DUF966 PF06136.8 ETO26623.1 - 6.8 6.0 11.0 8.4 5.6 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) PFK PF00365.15 ETO26624.1 - 6.4e-16 58.1 0.0 9e-16 57.6 0.0 1.1 1 0 0 1 1 1 1 Phosphofructokinase Metallophos PF00149.23 ETO26625.1 - 0.0071 15.7 0.0 0.014 14.8 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2259 PF10016.4 ETO26625.1 - 0.097 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Predicted secreted protein (DUF2259) TIP49 PF06068.8 ETO26626.1 - 2.8e-93 312.7 5.9 1.1e-69 235.1 0.4 3.0 2 1 0 2 2 2 2 TIP49 C-terminus AAA_22 PF13401.1 ETO26626.1 - 0.013 15.6 0.3 0.039 14.0 0.0 1.9 3 0 0 3 3 3 0 AAA domain RuvB_N PF05496.7 ETO26626.1 - 0.017 14.1 0.2 1.5 7.7 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 ETO26626.1 - 0.055 13.6 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF912 PF06024.7 ETO26627.1 - 0.0012 18.8 0.4 0.0012 18.8 0.2 3.7 4 1 0 4 4 4 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Ni_hydr_CYTB PF01292.15 ETO26627.1 - 0.0039 16.6 10.5 0.0039 16.6 7.3 2.2 2 0 0 2 2 2 1 Prokaryotic cytochrome b561 Nucleoplasmin PF03066.10 ETO26627.1 - 0.02 14.3 0.5 0.032 13.7 0.4 1.4 1 0 0 1 1 1 0 Nucleoplasmin RR_TM4-6 PF06459.7 ETO26627.1 - 0.24 11.2 4.5 0.16 11.8 1.3 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 BatD PF13584.1 ETO26627.1 - 0.54 8.7 2.3 0.71 8.4 0.2 2.1 1 1 1 2 2 2 0 Oxygen tolerance PBP1_TM PF14812.1 ETO26627.1 - 7.9 6.8 7.4 19 5.6 5.1 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TPR_12 PF13424.1 ETO26628.1 - 1.6e-34 117.6 3.1 1.4e-14 53.7 0.4 3.2 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO26628.1 - 1.5e-23 81.3 11.2 1.9e-06 27.2 1.1 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO26628.1 - 8.2e-21 72.1 1.6 0.00014 21.3 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO26628.1 - 4.1e-19 67.9 1.2 8.6e-11 41.3 0.5 2.7 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 ETO26628.1 - 1.4e-16 59.0 3.8 0.0011 18.6 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO26628.1 - 3.7e-16 57.6 11.4 0.00016 21.2 0.4 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO26628.1 - 5.1e-12 45.3 0.0 0.01 15.7 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO26628.1 - 3.2e-08 33.1 1.8 0.37 11.1 0.0 5.2 5 0 0 5 5 4 2 Tetratricopeptide repeat MIT PF04212.13 ETO26628.1 - 0.0014 18.4 3.9 0.3 10.9 0.0 3.8 3 1 1 4 4 4 1 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 ETO26628.1 - 0.0044 17.1 1.0 0.0044 17.1 0.7 2.5 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 ETO26628.1 - 0.13 12.9 0.0 1e+02 3.9 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETO26628.1 - 0.19 12.4 0.0 28 5.5 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat His_Phos_2 PF00328.17 ETO26630.1 - 9.3e-06 25.2 0.3 0.031 13.6 0.1 2.1 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 ETO26630.1 - 0.00021 21.4 0.0 0.0008 19.5 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF2861 PF11060.3 ETO26630.1 - 0.017 14.4 0.0 0.035 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2861) F-box PF00646.28 ETO26632.1 - 5.1e-05 22.8 0.0 0.00014 21.3 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 ETO26632.1 - 0.0011 18.5 0.0 0.0032 17.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like Monellin PF09200.5 ETO26633.1 - 0.097 12.3 0.3 0.8 9.3 0.1 2.5 2 0 0 2 2 2 0 Monellin Med3 PF11593.3 ETO26634.1 - 0.00024 20.4 17.4 0.00026 20.3 12.1 1.1 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal Hid1 PF12722.2 ETO26635.1 - 0.14 9.7 5.2 0.17 9.5 3.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CytochromB561_N PF09786.4 ETO26635.1 - 0.28 9.5 8.6 0.37 9.1 6.0 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal RR_TM4-6 PF06459.7 ETO26635.1 - 0.35 10.7 6.4 0.45 10.3 4.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.11 ETO26635.1 - 0.62 9.9 6.6 0.88 9.4 4.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Lumazine_bd PF12870.2 ETO26635.1 - 0.87 9.6 6.0 1.4 9.0 3.6 1.7 1 1 0 1 1 1 0 Lumazine-binding domain Mem_trans PF03547.13 ETO26635.1 - 2.2 6.4 4.9 2.7 6.1 3.4 1.1 1 0 0 1 1 1 0 Membrane transport protein Paramyxo_ncap PF00973.14 ETO26635.1 - 3.4 6.2 7.3 4.3 5.9 5.1 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein TRAPPC-Trs85 PF12739.2 ETO26636.1 - 1e-31 110.0 9.0 1.8e-31 109.2 6.2 1.5 1 1 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit GP40 PF11025.3 ETO26636.1 - 0.0074 15.8 4.0 0.013 15.0 2.8 1.3 1 0 0 1 1 1 1 Glycoprotein GP40 of Cryptosporidium Pox_RNA_Pol_22 PF05273.8 ETO26638.1 - 0.06 12.9 0.1 1.6 8.3 0.0 2.1 1 1 1 2 2 2 0 Poxvirus RNA polymerase 22 kDa subunit Tropomyosin PF00261.15 ETO26639.1 - 0.0026 16.9 1.9 0.0041 16.2 1.3 1.3 1 0 0 1 1 1 1 Tropomyosin ABC_tran PF00005.22 ETO26639.1 - 0.0046 17.2 0.5 0.0053 17.0 0.3 1.2 1 0 0 1 1 1 1 ABC transporter GAS PF13851.1 ETO26639.1 - 0.0087 15.2 7.3 0.014 14.6 5.1 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding AAA_32 PF13654.1 ETO26639.1 - 0.039 12.6 1.9 0.041 12.5 1.3 1.0 1 0 0 1 1 1 0 AAA domain SpecificRecomb PF10136.4 ETO26639.1 - 0.043 11.8 0.1 0.049 11.6 0.1 1.0 1 0 0 1 1 1 0 Site-specific recombinase Pneumo_M2 PF07380.6 ETO26639.1 - 0.053 13.5 1.0 0.1 12.5 0.5 1.6 1 1 0 1 1 1 0 Pneumovirus M2 protein Laminin_II PF06009.7 ETO26639.1 - 0.075 12.7 1.0 0.092 12.5 0.2 1.5 2 0 0 2 2 2 0 Laminin Domain II NinG PF05766.7 ETO26639.1 - 0.082 12.6 5.5 0.13 11.9 3.8 1.3 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein BLOC1_2 PF10046.4 ETO26639.1 - 0.11 12.6 3.4 0.15 12.2 1.7 1.7 2 0 0 2 2 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Vac_Fusion PF02346.11 ETO26639.1 - 0.11 11.9 1.6 1.3 8.5 0.2 2.6 1 1 1 2 2 2 0 Chordopoxvirus fusion protein ERp29 PF07749.7 ETO26639.1 - 0.12 13.0 2.2 0.19 12.3 1.3 1.5 2 0 0 2 2 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain DUF342 PF03961.8 ETO26639.1 - 0.16 10.3 3.2 0.17 10.2 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) GP41 PF00517.12 ETO26639.1 - 0.19 11.2 4.0 0.26 10.8 2.8 1.2 1 0 0 1 1 1 0 Retroviral envelope protein YkyA PF10368.4 ETO26639.1 - 0.26 10.5 6.3 0.17 11.2 2.9 1.8 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein DUF2654 PF10849.3 ETO26639.1 - 0.37 10.5 4.9 3.2 7.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2654) Ipi1_N PF12333.3 ETO26639.1 - 0.52 10.3 2.5 0.8 9.7 0.0 2.2 1 1 1 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation Uds1 PF15456.1 ETO26639.1 - 0.82 9.6 4.3 0.68 9.9 1.9 1.5 2 0 0 2 2 2 0 Up-regulated During Septation Myb_DNA-bind_6 PF13921.1 ETO26639.1 - 0.89 9.7 6.0 5 7.2 0.6 2.8 3 0 0 3 3 3 0 Myb-like DNA-binding domain DUF4612 PF15389.1 ETO26639.1 - 1 9.9 5.4 0.39 11.3 1.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4612) TMF_DNA_bd PF12329.3 ETO26639.1 - 2.9 7.7 10.0 0.22 11.3 3.4 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding WD40 PF00400.27 ETO26641.1 - 4.9e-72 235.4 11.0 3.1e-14 52.2 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO26641.1 - 2.1e-07 29.5 4.2 0.0095 14.1 0.4 4.2 1 1 0 2 2 2 2 Nucleoporin Nup120/160 PD40 PF07676.7 ETO26641.1 - 2.5e-06 26.9 0.4 1.8 8.3 0.0 4.7 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO26641.1 - 1.1e-05 24.3 7.8 0.29 9.8 0.2 5.1 1 1 3 4 4 4 2 Nup133 N terminal like Resistin PF06954.6 ETO26641.1 - 0.00056 20.1 0.1 0.19 12.0 0.1 3.4 3 0 0 3 3 3 1 Resistin Cytochrom_D1 PF02239.11 ETO26641.1 - 0.0028 16.0 1.3 5.3 5.2 0.0 3.0 1 1 1 3 3 3 2 Cytochrome D1 heme domain Gmad1 PF10647.4 ETO26641.1 - 0.018 14.4 0.0 0.74 9.1 0.0 2.8 3 1 0 3 3 3 0 Lipoprotein LpqB beta-propeller domain Hira PF07569.6 ETO26641.1 - 0.064 12.4 0.4 16 4.6 0.0 3.3 2 2 1 3 3 3 0 TUP1-like enhancer of split Peptidase_M48 PF01435.13 ETO26642.1 - 2.9e-10 40.0 0.7 3.4e-10 39.8 0.5 1.2 1 0 0 1 1 1 1 Peptidase family M48 VPS9 PF02204.13 ETO26643.1 - 1.4e-14 54.0 0.5 5e-14 52.1 0.0 2.1 2 1 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain CAP_GLY PF01302.20 ETO26643.1 - 1.8e-07 30.7 0.0 3.4e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain SR-25 PF10500.4 ETO26643.1 - 0.00079 18.9 9.3 0.00079 18.9 6.4 2.2 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein Nipped-B_C PF12830.2 ETO26643.1 - 0.1 12.2 3.2 9.5 5.8 2.2 2.7 1 1 0 1 1 1 0 Sister chromatid cohesion C-terminus DDHD PF02862.12 ETO26643.1 - 1.3 8.8 10.8 0.1 12.3 1.0 2.3 2 1 0 2 2 2 0 DDHD domain DUF4611 PF15387.1 ETO26643.1 - 2.6 8.2 11.6 2.9 8.1 4.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) BLVR PF06375.6 ETO26643.1 - 3.7 7.3 19.6 0.43 10.4 4.4 2.8 3 0 0 3 3 3 0 Bovine leukaemia virus receptor (BLVR) DUF3328 PF11807.3 ETO26644.1 - 0.0076 15.9 0.1 0.013 15.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF4525 PF15027.1 ETO26644.1 - 0.031 13.8 0.1 0.094 12.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) DUF310 PF03750.8 ETO26644.1 - 0.056 13.6 1.5 0.22 11.7 0.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF310) Claudin_2 PF13903.1 ETO26646.1 - 0.05 13.2 0.7 0.05 13.2 0.5 1.8 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction 2OG-FeII_Oxy_4 PF13661.1 ETO26647.1 - 1.7e-09 37.1 0.4 3.1e-09 36.3 0.3 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 ETO26647.1 - 4.9e-09 36.6 0.1 8.1e-09 35.9 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 ETO26647.1 - 0.00015 22.0 0.0 0.0003 21.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3173 PF11372.3 ETO26647.1 - 0.076 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3173) CAP18_C PF12153.3 ETO26647.1 - 0.21 11.2 2.1 3.9 7.2 0.1 2.5 2 0 0 2 2 2 0 LPS binding domain of CAP18 (C terminal) Macoilin PF09726.4 ETO26648.1 - 0.3 9.3 23.5 0.35 9.1 16.3 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF566 PF04484.7 ETO26648.1 - 0.37 10.2 18.9 0.53 9.7 13.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) MBT PF02820.13 ETO26649.1 - 0.0049 16.7 0.2 0.043 13.7 0.0 2.1 2 0 0 2 2 2 1 mbt repeat DUF3306 PF11748.3 ETO26649.1 - 0.4 11.3 3.6 0.52 10.9 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Rpp20 PF12328.3 ETO26650.1 - 0.35 10.5 2.4 0.55 9.8 1.6 1.2 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P ESCRT-II PF05871.7 ETO26651.1 - 2.2e-41 141.0 0.5 2.8e-41 140.6 0.4 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit LisH PF08513.6 ETO26651.1 - 0.081 12.7 0.6 0.27 11.0 0.0 2.0 2 0 0 2 2 2 0 LisH Dynein_heavy PF03028.10 ETO26652.1 - 8.8e-107 357.9 0.0 1e-106 357.6 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor DUF749 PF05370.6 ETO26652.1 - 0.07 13.0 0.3 0.82 9.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF749) MCPsignal PF00015.16 ETO26652.1 - 0.079 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain AAA_6 PF12774.2 ETO26653.1 - 9.3e-122 404.8 0.1 3.2e-121 403.1 0.0 2.0 2 0 0 2 2 1 1 Hydrolytic ATP binding site of dynein motor region D1 DHC_N2 PF08393.8 ETO26653.1 - 1.1e-121 406.2 8.2 1.1e-121 406.2 5.7 5.3 5 1 0 6 6 5 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.7 ETO26653.1 - 4.3e-120 401.8 20.2 4.3e-120 401.8 14.0 4.8 5 2 0 5 5 4 1 Dynein heavy chain, N-terminal region 1 AAA_8 PF12780.2 ETO26653.1 - 5.8e-99 330.3 1.0 1.3e-98 329.2 0.2 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 ETO26653.1 - 4e-80 268.7 2.4 8.5e-80 267.7 0.2 2.5 3 0 0 3 3 2 1 P-loop containing dynein motor region D3 AAA_9 PF12781.2 ETO26653.1 - 1.2e-65 220.6 0.5 2.7e-65 219.4 0.3 1.6 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 ETO26653.1 - 3.8e-60 203.4 31.5 4.7e-59 199.8 21.8 2.4 1 1 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.10 ETO26653.1 - 5.5e-54 183.3 0.1 1.6e-53 181.8 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_5 PF07728.9 ETO26653.1 - 1.8e-19 69.8 1.0 3.8e-05 23.4 0.0 8.5 6 3 1 7 7 7 4 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 ETO26653.1 - 2.4e-07 31.5 0.5 0.13 13.0 0.0 5.6 5 0 0 5 5 3 2 AAA domain AAA_22 PF13401.1 ETO26653.1 - 3.9e-07 30.2 0.6 0.39 10.8 0.0 5.4 5 0 0 5 5 5 2 AAA domain AAA_16 PF13191.1 ETO26653.1 - 9.1e-07 29.0 7.9 0.79 9.6 0.0 6.6 7 0 0 7 7 6 2 AAA ATPase domain AAA PF00004.24 ETO26653.1 - 1.5e-05 25.1 0.3 1.2 9.3 0.0 5.5 5 0 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 ETO26653.1 - 5.7e-05 22.7 0.0 0.058 12.9 0.0 3.9 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 ETO26653.1 - 0.00021 21.6 0.9 0.76 10.0 0.0 5.4 5 0 0 5 5 4 1 AAA domain AAA_33 PF13671.1 ETO26653.1 - 0.0025 17.6 0.5 6.3 6.6 0.0 5.0 5 0 0 5 5 5 1 AAA domain AAA_19 PF13245.1 ETO26653.1 - 0.0029 17.3 1.2 14 5.4 0.0 3.9 3 0 0 3 3 3 0 Part of AAA domain AP_endonuc_2 PF01261.19 ETO26653.1 - 0.036 13.3 0.0 0.15 11.3 0.0 2.1 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Mg_chelatase PF01078.16 ETO26653.1 - 0.037 13.1 0.0 1.9 7.6 0.0 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI rve_3 PF13683.1 ETO26653.1 - 0.044 13.3 1.9 6.8 6.3 0.0 4.3 4 0 0 4 4 3 0 Integrase core domain AAA_29 PF13555.1 ETO26653.1 - 0.064 12.7 0.2 22 4.6 0.0 3.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain ABC_tran PF00005.22 ETO26653.1 - 1 9.6 6.2 6.6 7.0 0.0 4.8 5 0 0 5 5 3 0 ABC transporter FUSC PF04632.7 ETO26653.1 - 4.7 5.5 2.5 12 4.2 1.7 1.6 1 0 0 1 1 1 0 Fusaric acid resistance protein family WD40 PF00400.27 ETO26655.1 - 3.6e-22 77.3 7.9 3.5e-08 33.0 0.0 5.4 4 1 1 5 5 5 4 WD domain, G-beta repeat WD40 PF00400.27 ETO26656.1 - 2.8e-57 188.6 13.2 1.3e-12 47.0 0.6 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO26656.1 - 9.5e-10 37.2 6.8 0.0032 15.6 0.2 4.9 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO26656.1 - 5.5e-05 21.6 1.6 0.0039 15.5 0.1 3.0 1 1 3 4 4 4 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO26656.1 - 0.0004 19.9 0.0 0.0034 16.8 0.0 2.0 1 1 1 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 ETO26656.1 - 0.004 15.9 15.5 0.18 10.5 1.6 2.8 1 1 1 2 2 2 2 Nup133 N terminal like PTB PF08416.8 ETO26656.1 - 0.011 15.6 0.5 0.42 10.5 0.0 2.8 1 1 1 2 2 2 0 Phosphotyrosine-binding domain SGL PF08450.7 ETO26656.1 - 0.013 14.8 0.4 0.027 13.8 0.1 1.6 2 0 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region Ricin_B_lectin PF00652.17 ETO26656.1 - 0.038 14.0 0.7 1.5 8.8 0.1 2.9 2 1 2 4 4 4 0 Ricin-type beta-trefoil lectin domain DPPIV_N PF00930.16 ETO26656.1 - 0.039 12.5 0.3 0.37 9.3 0.1 2.6 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Hjc PF01870.13 ETO26656.1 - 0.42 10.2 4.6 1.3 8.6 0.1 2.8 3 0 0 3 3 3 0 Archaeal holliday junction resolvase (hjc) Kelch_1 PF01344.20 ETO26657.1 - 3.6e-06 26.4 5.4 0.00028 20.3 0.5 4.2 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO26657.1 - 9e-06 25.3 0.3 0.063 13.0 0.0 3.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO26657.1 - 8.1e-05 22.6 5.1 0.96 9.7 0.1 4.7 4 1 1 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO26657.1 - 0.0008 19.0 3.7 0.35 10.7 0.1 4.5 4 1 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 ETO26657.1 - 0.0049 17.0 0.1 0.15 12.2 0.0 3.1 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO26657.1 - 0.31 11.0 5.6 9.5 6.2 0.0 4.3 5 0 0 5 5 5 0 Kelch motif Pentaxin PF00354.12 ETO26657.1 - 0.46 9.8 6.1 0.35 10.2 0.1 2.8 3 0 0 3 3 3 0 Pentaxin family Kelch_6 PF13964.1 ETO26658.1 - 2.2e-09 37.0 1.8 1.1e-05 25.3 0.0 4.0 4 0 0 4 4 4 2 Kelch motif U-box PF04564.10 ETO26658.1 - 2.8e-09 36.8 0.3 1.5e-08 34.4 0.0 2.4 2 0 0 2 2 2 1 U-box domain Kelch_1 PF01344.20 ETO26658.1 - 1.9e-08 33.7 3.1 8.9e-06 25.1 0.1 3.6 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 ETO26658.1 - 2.6e-05 24.2 0.1 0.00022 21.2 0.0 2.5 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO26658.1 - 4.6e-05 23.0 0.7 0.00027 20.6 0.0 2.7 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO26658.1 - 0.086 12.8 0.1 1.4 8.9 0.0 2.7 2 0 0 2 2 2 0 Kelch motif Kelch_1 PF01344.20 ETO26659.1 - 1.7e-08 33.8 5.1 0.00012 21.5 0.1 4.5 4 0 0 4 4 4 3 Kelch motif U-box PF04564.10 ETO26659.1 - 2.2e-08 33.9 0.6 9.9e-08 31.8 0.0 2.4 2 1 0 2 2 2 1 U-box domain Kelch_6 PF13964.1 ETO26659.1 - 9.9e-07 28.6 7.4 0.00042 20.3 0.0 5.2 4 2 1 5 5 5 2 Kelch motif Kelch_3 PF13415.1 ETO26659.1 - 5.3e-06 26.4 0.3 0.00032 20.7 0.0 3.3 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO26659.1 - 8.7e-05 22.2 1.5 0.002 17.8 0.0 3.5 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO26659.1 - 0.0015 18.4 1.2 0.014 15.3 0.0 3.0 4 0 0 4 4 4 1 Kelch motif PAZ PF02170.17 ETO26660.1 - 6.6e-09 35.1 0.3 1.2e-08 34.3 0.2 1.4 1 0 0 1 1 1 1 PAZ domain Piwi PF02171.12 ETO26660.1 - 7e-05 21.9 0.0 0.00012 21.2 0.0 1.3 1 0 0 1 1 1 1 Piwi domain Shisa PF13908.1 ETO26660.1 - 0.025 14.7 0.5 0.047 13.8 0.3 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Chorion_3 PF05387.6 ETO26661.1 - 0.038 13.4 2.9 0.064 12.6 2.0 1.3 1 0 0 1 1 1 0 Chorion family 3 DUF4131 PF13567.1 ETO26661.1 - 0.11 11.9 9.2 0.29 10.5 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DctQ PF04290.7 ETO26661.1 - 0.37 10.5 8.5 0.085 12.6 1.5 2.4 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF2101 PF09874.4 ETO26661.1 - 1.6 8.1 5.2 3.1 7.2 3.6 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) PRA1 PF03208.14 ETO26661.1 - 6.6 6.0 15.3 1.8 7.9 7.4 2.3 2 1 0 2 2 2 0 PRA1 family protein cobW PF02492.14 ETO26662.1 - 7.6e-42 142.7 0.2 1.4e-41 141.9 0.1 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 ETO26662.1 - 2.4e-09 36.7 0.0 6e-09 35.4 0.0 1.6 2 0 0 2 2 1 1 Cobalamin synthesis protein cobW C-terminal domain KTI12 PF08433.5 ETO26662.1 - 3.7e-05 23.0 0.0 8.3e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 Chromatin associated protein KTI12 MobB PF03205.9 ETO26662.1 - 3.7e-05 23.4 0.1 9.6e-05 22.1 0.1 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 ETO26662.1 - 8.1e-05 22.6 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 ETO26662.1 - 0.0008 19.7 3.0 0.00099 19.4 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_10 PF12846.2 ETO26662.1 - 0.00093 18.7 0.5 0.003 17.0 0.0 1.8 2 0 0 2 2 2 1 AAA-like domain ArgK PF03308.11 ETO26662.1 - 0.00095 18.0 0.2 0.0022 16.8 0.0 1.6 2 0 0 2 2 2 1 ArgK protein T2SE PF00437.15 ETO26662.1 - 0.00098 18.0 1.2 0.0018 17.1 0.3 1.7 2 1 1 3 3 2 1 Type II/IV secretion system protein Arch_ATPase PF01637.13 ETO26662.1 - 0.0012 18.5 0.7 0.018 14.7 0.0 2.2 2 0 0 2 2 2 1 Archaeal ATPase NTPase_1 PF03266.10 ETO26662.1 - 0.0013 18.4 0.6 0.0032 17.2 0.2 1.8 2 0 0 2 2 2 1 NTPase SRP54 PF00448.17 ETO26662.1 - 0.004 16.6 0.1 0.01 15.3 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.18 ETO26662.1 - 0.0069 16.3 1.6 0.015 15.2 0.3 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_19 PF13245.1 ETO26662.1 - 0.0084 15.8 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 ETO26662.1 - 0.01 15.9 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 ETO26662.1 - 0.011 14.9 0.7 0.029 13.5 0.5 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF258 TrwB_AAD_bind PF10412.4 ETO26662.1 - 0.011 14.3 0.0 0.02 13.5 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_14 PF13173.1 ETO26662.1 - 0.012 15.4 0.0 0.034 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 ETO26662.1 - 0.013 14.7 0.6 0.07 12.3 0.1 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Pox_A32 PF04665.7 ETO26662.1 - 0.014 14.6 1.2 0.21 10.8 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein ATP_bind_1 PF03029.12 ETO26662.1 - 0.016 14.7 0.1 0.067 12.7 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein KAP_NTPase PF07693.9 ETO26662.1 - 0.017 14.1 0.1 0.017 14.1 0.0 1.6 2 1 0 2 2 2 0 KAP family P-loop domain NACHT PF05729.7 ETO26662.1 - 0.028 14.0 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Viral_helicase1 PF01443.13 ETO26662.1 - 0.033 13.7 0.5 0.064 12.7 0.0 1.7 2 0 0 2 2 1 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.1 ETO26662.1 - 0.04 13.7 0.0 0.084 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 ETO26662.1 - 0.056 12.9 0.1 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain UPF0079 PF02367.12 ETO26662.1 - 0.069 12.7 0.1 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 ETO26662.1 - 0.074 13.0 0.1 0.29 11.0 0.1 2.0 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 ETO26662.1 - 0.079 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase CbiA PF01656.18 ETO26662.1 - 0.093 12.1 1.1 0.34 10.3 0.7 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain FtsK_SpoIIIE PF01580.13 ETO26662.1 - 0.095 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF87 PF01935.12 ETO26662.1 - 0.2 11.4 9.0 0.041 13.6 1.8 2.6 2 1 0 2 2 2 0 Domain of unknown function DUF87 AAA_17 PF13207.1 ETO26662.1 - 0.75 10.6 5.4 0.28 12.0 0.6 2.6 2 2 0 2 2 2 0 AAA domain AF1Q PF15017.1 ETO26662.1 - 2.4 8.1 10.1 2.2 8.2 3.5 2.6 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator Actino_peptide PF14408.1 ETO26662.1 - 9.4 6.2 9.3 15 5.6 0.8 3.5 3 0 0 3 3 3 0 Ribosomally synthesized peptide in actinomycetes Dynamin_N PF00350.18 ETO26663.1 - 1.4e-14 54.3 0.0 5.8e-14 52.2 0.0 1.9 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 ETO26663.1 - 4.6e-05 23.3 0.0 0.00063 19.6 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 ETO26663.1 - 0.0034 17.8 0.0 0.0075 16.7 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein UPF0079 PF02367.12 ETO26663.1 - 0.075 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 ETO26663.1 - 0.088 12.7 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF927 PF06048.6 ETO26663.1 - 0.096 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF927) Sdh_cyt PF01127.17 ETO26664.1 - 0.001 18.8 8.9 0.001 18.8 6.1 3.0 2 2 0 2 2 2 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF4200 PF13863.1 ETO26665.1 - 4.3e-09 36.3 31.4 4.3e-09 36.3 21.8 3.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4200) RibD_C PF01872.12 ETO26665.1 - 0.57 9.7 3.3 0.89 9.1 2.3 1.3 1 0 0 1 1 1 0 RibD C-terminal domain DUF4520 PF15016.1 ETO26667.1 - 1.1e-07 31.3 0.1 3.9e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4520) Brix PF04427.13 ETO26668.1 - 1.9e-12 47.2 2.0 5.9e-12 45.6 1.4 1.9 1 1 0 1 1 1 1 Brix domain DUF790 PF05626.6 ETO26668.1 - 0.061 11.8 0.0 0.078 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF790) Trichoplein PF13868.1 ETO26670.1 - 6e-30 103.8 121.3 7.1e-28 97.0 80.1 3.1 3 0 0 3 3 3 2 Tumour suppressor, Mitostatin ESSS PF10183.4 ETO26671.1 - 6.2 7.2 5.2 2 8.8 0.1 2.8 4 0 0 4 4 4 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Spc7 PF08317.6 ETO26672.1 - 0.00077 18.2 10.8 0.00088 18.0 7.5 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Baculo_PEP_C PF04513.7 ETO26672.1 - 0.0075 16.1 14.2 0.1 12.4 5.4 2.1 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3829 PF12889.2 ETO26672.1 - 0.011 14.8 10.2 0.016 14.3 6.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3829) Meth_synt_1 PF08267.7 ETO26672.1 - 0.029 13.6 4.3 0.033 13.4 3.0 1.2 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain DUF4349 PF14257.1 ETO26672.1 - 0.029 13.6 0.9 0.04 13.1 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF3584 PF12128.3 ETO26672.1 - 0.029 11.7 11.1 0.036 11.4 7.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NPV_P10 PF05531.7 ETO26672.1 - 0.039 14.2 13.7 5.6 7.2 8.8 3.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein 7TMR-HDED PF07697.6 ETO26672.1 - 0.04 13.6 5.2 0.051 13.2 3.6 1.3 1 0 0 1 1 1 0 7TM-HD extracellular DivIVA PF05103.8 ETO26672.1 - 0.043 13.8 13.5 0.031 14.3 8.3 1.5 1 1 0 1 1 1 0 DivIVA protein PqqD PF05402.7 ETO26672.1 - 0.046 13.7 0.2 2.2 8.3 0.1 2.4 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) Seryl_tRNA_N PF02403.17 ETO26672.1 - 0.047 13.7 13.8 0.077 13.0 5.9 2.6 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Cast PF10174.4 ETO26672.1 - 0.047 11.7 12.8 0.058 11.4 8.9 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone FUSC-like PF12805.2 ETO26672.1 - 0.064 12.1 3.1 0.11 11.3 2.1 1.5 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Reo_sigmaC PF04582.7 ETO26672.1 - 0.071 12.2 3.3 0.1 11.7 2.3 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein APG6 PF04111.7 ETO26672.1 - 0.077 12.0 11.9 0.099 11.6 8.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2132 PF09905.4 ETO26672.1 - 0.08 12.9 0.5 0.68 9.9 0.0 2.6 2 2 1 3 3 2 0 Uncharacterized conserved protein (DUF2132) HsbA PF12296.3 ETO26672.1 - 0.088 12.6 2.9 0.26 11.1 1.0 2.3 1 1 1 2 2 2 0 Hydrophobic surface binding protein A TrbI_Ftype PF09677.5 ETO26672.1 - 0.088 12.6 0.5 0.088 12.6 0.3 2.0 2 1 0 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) Syntaxin-6_N PF09177.6 ETO26672.1 - 0.12 12.8 9.5 0.12 12.8 5.2 1.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal CK2S PF15011.1 ETO26672.1 - 0.15 11.8 6.3 0.86 9.3 2.4 2.6 1 1 1 2 2 2 0 Casein Kinase 2 substrate DUF445 PF04286.7 ETO26672.1 - 0.15 11.5 9.1 0.19 11.1 6.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Imm5 PF14423.1 ETO26672.1 - 0.17 11.5 5.8 0.22 11.1 4.0 1.2 1 0 0 1 1 1 0 Immunity protein Imm5 Thoc2 PF11732.3 ETO26672.1 - 0.22 11.3 2.1 0.45 10.3 0.5 2.1 2 0 0 2 2 2 0 Transcription- and export-related complex subunit FlaC_arch PF05377.6 ETO26672.1 - 0.25 11.2 14.3 0.22 11.4 0.8 3.4 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) PglZ PF08665.7 ETO26672.1 - 0.36 10.4 6.4 0.86 9.2 4.4 1.8 1 1 0 1 1 1 0 PglZ domain Sds3 PF08598.6 ETO26672.1 - 0.45 9.9 11.7 0.57 9.6 0.3 2.6 1 1 1 2 2 2 0 Sds3-like GxGYxYP PF14323.1 ETO26672.1 - 0.46 9.1 7.4 0.72 8.4 5.1 1.4 1 1 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function Ax_dynein_light PF10211.4 ETO26672.1 - 0.5 10.1 14.2 0.83 9.4 9.3 1.7 1 1 0 1 1 1 0 Axonemal dynein light chain RapA_C PF12137.3 ETO26672.1 - 0.57 8.9 10.1 0.73 8.5 7.0 1.1 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal TPR_MLP1_2 PF07926.7 ETO26672.1 - 0.6 9.8 16.7 1.6 8.4 11.6 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein AAA_23 PF13476.1 ETO26672.1 - 0.61 10.3 10.8 0.95 9.7 7.5 1.3 1 0 0 1 1 1 0 AAA domain Fib_alpha PF08702.5 ETO26672.1 - 0.72 9.9 15.8 1.5 8.9 10.2 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family H-kinase_dim PF02895.9 ETO26672.1 - 0.75 10.1 3.6 21 5.5 2.5 2.7 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain HAUS6_N PF14661.1 ETO26672.1 - 0.8 9.0 10.4 0.97 8.7 7.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF2203 PF09969.4 ETO26672.1 - 0.83 9.8 11.0 1.6 8.9 2.6 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF342 PF03961.8 ETO26672.1 - 0.93 7.8 13.9 3 6.1 9.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF4164 PF13747.1 ETO26672.1 - 1.3 9.1 7.0 3.4 7.8 3.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Allexi_40kDa PF05549.6 ETO26672.1 - 1.5 8.0 10.2 1.1 8.5 5.8 1.6 1 1 1 2 2 2 0 Allexivirus 40kDa protein Orbi_VP5 PF00901.12 ETO26672.1 - 1.9 6.5 10.1 2.3 6.3 7.0 1.0 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 SPX PF03105.14 ETO26672.1 - 2.1 8.0 9.1 3.1 7.5 6.3 1.3 1 0 0 1 1 1 0 SPX domain Atg14 PF10186.4 ETO26672.1 - 2.1 7.2 12.1 0.24 10.3 4.5 1.8 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF948 PF06103.6 ETO26672.1 - 2.6 7.9 15.8 5.5 6.9 5.4 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 ETO26672.1 - 3.6 7.1 10.2 7.1 6.1 6.9 1.5 1 1 0 1 1 1 0 IncA protein DUF607 PF04678.8 ETO26672.1 - 4.1 7.2 9.0 4.6 7.1 5.2 1.9 1 1 1 2 2 2 0 Protein of unknown function, DUF607 DASH_Dad2 PF08654.5 ETO26672.1 - 4.2 7.4 10.2 1.1 9.2 2.0 2.8 2 1 1 3 3 3 0 DASH complex subunit Dad2 DUF1664 PF07889.7 ETO26672.1 - 4.4 7.1 11.4 6.8 6.5 7.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Adeno_PIX PF03955.9 ETO26672.1 - 4.6 7.8 8.1 13 6.3 2.0 2.3 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) Occludin_ELL PF07303.8 ETO26672.1 - 5.5 7.7 10.5 1.6 9.4 4.2 2.0 1 1 1 2 2 2 0 Occludin homology domain DUF2408 PF10303.4 ETO26672.1 - 6.2 6.9 13.8 33 4.5 9.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) HALZ PF02183.13 ETO26672.1 - 8.5 6.1 9.8 17 5.1 0.1 3.3 2 1 1 3 3 3 0 Homeobox associated leucine zipper Z1 PF10593.4 ETO26672.1 - 9.2 5.3 12.2 26 3.8 8.5 1.7 1 1 0 1 1 1 0 Z1 domain DUF3782 PF12644.2 ETO26672.1 - 9.9 6.0 7.4 14 5.5 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3782) Nucleoside_tran PF01733.13 ETO26673.1 - 4.9e-14 52.2 0.5 4.9e-14 52.2 0.3 2.3 2 1 1 3 3 3 1 Nucleoside transporter Daxx PF03344.10 ETO26673.1 - 0.078 11.4 23.9 0.1 11.1 16.6 1.1 1 0 0 1 1 1 0 Daxx Family FtsL PF04999.8 ETO26673.1 - 0.15 11.8 0.8 0.32 10.7 0.0 2.0 2 0 0 2 2 2 0 Cell division protein FtsL DUF506 PF04720.7 ETO26673.1 - 2.7 7.5 8.4 5.3 6.6 5.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Utp14 PF04615.8 ETO26673.1 - 3.1 5.8 26.3 3.7 5.5 18.2 1.1 1 0 0 1 1 1 0 Utp14 protein DUF2138 PF09909.4 ETO26673.1 - 3.4 5.7 5.1 0.33 9.0 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2138) MIP-T3 PF10243.4 ETO26673.1 - 5.2 5.4 22.4 6.7 5.0 15.5 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CAP_GLY PF01302.20 ETO26674.1 - 8.6e-12 44.5 0.1 1.7e-11 43.6 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain RhoGEF PF00621.15 ETO26675.1 - 4.5e-11 42.9 6.0 4.5e-11 42.9 4.1 2.0 2 1 0 2 2 2 1 RhoGEF domain Med27 PF11571.3 ETO26675.1 - 2.8 8.1 9.1 9.3 6.4 0.1 3.1 2 1 1 3 3 3 0 Mediator complex subunit 27 RabGAP-TBC PF00566.13 ETO26676.1 - 0.00036 20.0 0.1 0.00038 19.9 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF2818 PF10993.3 ETO26676.1 - 0.01 16.3 0.2 0.013 15.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2818) G-alpha PF00503.15 ETO26677.1 - 3.9e-07 29.0 0.1 7.1e-07 28.2 0.0 1.4 1 1 0 1 1 1 1 G-protein alpha subunit CoaE PF01121.15 ETO26678.1 - 5.6e-44 149.6 0.0 7.4e-44 149.2 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.1 ETO26678.1 - 3.9e-05 23.9 0.5 0.00011 22.4 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO26678.1 - 7e-05 23.6 0.8 0.00017 22.3 0.5 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETO26678.1 - 0.0037 17.1 0.1 0.17 11.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain DUF4207 PF13904.1 ETO26678.1 - 0.021 14.2 1.3 0.029 13.7 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) SKI PF01202.17 ETO26678.1 - 0.031 14.1 0.6 7.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase AAA_28 PF13521.1 ETO26678.1 - 0.086 12.7 0.1 0.35 10.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain rve_3 PF13683.1 ETO26678.1 - 0.12 11.9 0.1 0.29 10.7 0.1 1.6 1 0 0 1 1 1 0 Integrase core domain DUF4613 PF15390.1 ETO26679.1 - 3.3 5.7 7.5 4.2 5.4 5.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Ank_2 PF12796.2 ETO26680.1 - 8.4e-20 70.9 6.1 8.5e-12 45.2 0.6 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO26680.1 - 4.2e-17 62.1 10.2 1.1e-10 41.6 0.5 3.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 ETO26680.1 - 1.3e-15 56.3 6.6 7.5e-05 22.3 0.4 4.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 ETO26680.1 - 7.8e-14 51.3 5.0 0.00022 21.3 0.3 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO26680.1 - 4.8e-12 44.8 9.6 0.0016 18.5 0.3 5.1 5 0 0 5 5 5 3 Ankyrin repeat SpoU_sub_bind PF08032.7 ETO26680.1 - 0.062 13.4 1.6 1.2 9.3 0.0 2.8 3 0 0 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding Ank_2 PF12796.2 ETO26681.1 - 6.5e-13 48.8 0.0 1.5e-12 47.6 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO26681.1 - 7.2e-11 41.3 0.5 8.6e-09 34.7 0.2 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 ETO26681.1 - 3e-10 40.0 0.5 2.5e-08 33.8 0.2 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO26681.1 - 3.1e-10 39.2 0.5 5.4e-08 32.3 0.1 3.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 ETO26681.1 - 4.6e-09 36.5 0.0 1.8e-08 34.6 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF2207 PF09972.4 ETO26682.1 - 0.00072 18.2 6.8 0.0039 15.8 0.8 2.0 1 1 0 2 2 2 2 Predicted membrane protein (DUF2207) DUF106 PF01956.11 ETO26682.1 - 0.0042 16.6 5.4 0.0051 16.3 2.4 1.9 1 1 1 2 2 2 1 Integral membrane protein DUF106 DUF3595 PF12166.3 ETO26682.1 - 0.0093 14.8 4.3 0.0099 14.7 2.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3595) DUF3899 PF13038.1 ETO26682.1 - 0.014 15.5 3.7 0.014 15.5 2.6 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3899) DUF3328 PF11807.3 ETO26682.1 - 0.047 13.3 0.0 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) DUF1673 PF07895.6 ETO26682.1 - 0.052 13.0 2.8 0.072 12.6 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1673) DUF1183 PF06682.7 ETO26682.1 - 0.055 13.0 0.1 0.16 11.5 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1183) DUF912 PF06024.7 ETO26682.1 - 0.12 12.4 0.0 0.12 12.4 0.0 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Tom37_C PF11801.3 ETO26682.1 - 1.2 8.9 4.9 17 5.2 3.8 2.0 2 0 0 2 2 2 0 Tom37 C-terminal domain DUF3671 PF12420.3 ETO26682.1 - 2.2 8.3 10.6 8.7 6.3 3.6 2.5 2 1 0 2 2 2 0 Protein of unknown function PS_Dcarbxylase PF02666.10 ETO26683.1 - 4e-48 163.4 0.1 4.6e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase DUF45 PF01863.12 ETO26684.1 - 0.26 11.0 9.2 0.044 13.5 3.8 1.5 2 0 0 2 2 2 0 Protein of unknown function DUF45 Transformer PF06495.6 ETO26684.1 - 4 7.2 8.4 0.5 10.2 3.2 1.4 2 0 0 2 2 2 0 Fruit fly transformer protein Afi1 PF07792.7 ETO26685.1 - 1.3 9.0 9.0 1.9 8.5 6.3 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PAP_assoc PF03828.14 ETO26686.1 - 8.1e-13 48.1 3.9 2.8e-12 46.4 2.7 2.0 1 1 0 1 1 1 1 Cid1 family poly A polymerase AA_permease_2 PF13520.1 ETO26686.1 - 0.036 12.5 2.1 0.057 11.9 1.5 1.2 1 0 0 1 1 1 0 Amino acid permease CENP-F_leu_zip PF10473.4 ETO26687.1 - 0.83 9.5 7.3 0.13 12.1 2.2 1.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tubulin PF00091.20 ETO26688.1 - 6.2e-36 124.2 0.0 6.9e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.4 ETO26688.1 - 2.8e-07 30.5 0.0 3.1e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Zip PF02535.17 ETO26689.1 - 1.8 7.4 13.3 0.078 11.9 5.1 1.7 1 1 1 2 2 2 0 ZIP Zinc transporter E_Pc_C PF06752.7 ETO26689.1 - 1.9 7.9 16.4 3.3 7.1 11.4 1.4 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus Dirigent PF03018.9 ETO26691.1 - 0.068 12.6 0.1 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Dirigent-like protein TPR_11 PF13414.1 ETO26692.1 - 9e-12 44.4 7.6 7.2e-07 28.7 0.4 3.5 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 ETO26692.1 - 3.2e-08 32.8 3.7 0.0089 15.8 0.1 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO26692.1 - 1.7e-07 30.5 7.6 0.0023 17.4 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO26692.1 - 1.5e-05 24.8 7.8 0.015 15.2 0.6 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO26692.1 - 0.0017 18.7 1.4 1.1 10.1 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO26692.1 - 0.002 17.7 6.0 4.6 7.2 0.1 4.4 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO26692.1 - 0.0035 17.9 0.4 0.17 12.6 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO26692.1 - 0.0066 16.1 0.6 4.1 7.4 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETO26692.1 - 0.033 14.0 0.4 0.099 12.5 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETO26692.1 - 0.053 13.8 7.6 0.06 13.6 0.5 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat NPL4 PF05021.10 ETO26693.1 - 2.4e-38 132.0 0.0 3.5e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 NPL4 family UN_NPL4 PF11543.3 ETO26693.1 - 7.2e-11 42.2 0.0 3.3e-10 40.1 0.0 2.1 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 Ubiquitin_2 PF14560.1 ETO26693.1 - 0.0022 18.1 0.0 0.0097 16.1 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-like domain zf-NPL4 PF05020.10 ETO26693.1 - 0.015 14.9 0.4 0.049 13.2 0.3 1.9 1 1 0 1 1 1 0 NPL4 family, putative zinc binding region ubiquitin PF00240.18 ETO26693.1 - 0.033 13.5 0.1 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin family LEA_3 PF03242.8 ETO26693.1 - 0.052 13.7 1.3 11 6.3 0.1 2.5 2 0 0 2 2 2 0 Late embryogenesis abundant protein BNIP3 PF06553.7 ETO26693.1 - 0.074 12.4 2.7 0.13 11.6 1.9 1.3 1 0 0 1 1 1 0 BNIP3 AMP-binding_C_2 PF14535.1 ETO26693.1 - 0.096 12.7 0.0 2.2 8.4 0.0 2.4 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Pkinase PF00069.20 ETO26695.1 - 5.8e-12 45.3 0.3 1.1e-11 44.3 0.2 1.5 1 0 0 1 1 1 1 Protein kinase domain Ion_trans PF00520.26 ETO26696.1 - 1e-13 51.0 16.7 2e-13 50.0 11.6 1.5 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.7 ETO26696.1 - 7.2e-06 24.6 13.2 1.2e-05 23.9 9.2 1.3 1 0 0 1 1 1 1 Polycystin cation channel Pkinase PF00069.20 ETO26697.1 - 1e-40 139.5 0.0 1.2e-40 139.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO26697.1 - 7.3e-20 71.1 0.0 9.2e-20 70.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO26697.1 - 0.027 13.4 0.0 0.035 13.0 0.0 1.1 1 0 0 1 1 1 0 Kinase-like PBP1_TM PF14812.1 ETO26698.1 - 0.018 15.3 2.1 0.027 14.7 0.1 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glycos_transf_1 PF00534.15 ETO26699.1 - 3.1e-13 49.4 0.0 6.1e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 ETO26699.1 - 0.00021 21.4 0.0 0.00035 20.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 NAD_binding_10 PF13460.1 ETO26699.1 - 0.034 14.1 0.0 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 NADH(P)-binding 3HCDH_N PF02737.13 ETO26699.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Daxx PF03344.10 ETO26700.1 - 0.11 10.9 13.5 0.31 9.4 1.5 2.1 2 0 0 2 2 2 0 Daxx Family Nop14 PF04147.7 ETO26700.1 - 0.31 8.9 15.0 0.46 8.3 3.3 2.1 2 0 0 2 2 2 0 Nop14-like family Zip PF02535.17 ETO26700.1 - 1.2 8.1 9.2 5.2 5.9 2.1 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter TPR_12 PF13424.1 ETO26702.1 - 9.9e-90 294.5 32.2 1.7e-18 66.3 0.0 8.5 7 1 3 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 ETO26702.1 - 1.8e-56 187.6 32.1 2.5e-11 43.0 0.1 9.9 4 3 5 10 10 10 9 TPR repeat TPR_1 PF00515.23 ETO26702.1 - 1.3e-50 166.9 47.2 0.00014 21.3 1.3 14.7 14 2 0 14 14 14 11 Tetratricopeptide repeat TPR_2 PF07719.12 ETO26702.1 - 2.5e-42 139.4 45.4 0.0019 17.9 0.6 14.3 14 0 0 14 14 14 13 Tetratricopeptide repeat TPR_10 PF13374.1 ETO26702.1 - 4.6e-37 124.8 14.7 5.9e-06 26.0 0.0 12.6 13 0 0 13 13 13 7 Tetratricopeptide repeat TPR_7 PF13176.1 ETO26702.1 - 2.7e-33 111.0 17.5 0.00066 19.2 0.1 13.8 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETO26702.1 - 3.2e-30 101.6 29.8 0.0066 16.1 0.9 14.3 14 1 0 14 14 14 11 Tetratricopeptide repeat TPR_14 PF13428.1 ETO26702.1 - 9.4e-19 66.2 9.8 0.87 10.4 0.0 11.9 11 1 1 12 12 12 4 Tetratricopeptide repeat TPR_6 PF13174.1 ETO26702.1 - 2.4e-18 65.2 15.0 0.025 15.0 0.0 12.1 13 0 0 13 13 13 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO26702.1 - 1.4e-17 63.6 25.7 0.00061 19.8 1.7 8.1 2 2 6 8 8 8 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 ETO26702.1 - 1.7e-12 47.6 17.5 0.14 12.8 0.4 8.4 6 2 2 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO26702.1 - 2.1e-11 43.0 7.9 6.2 7.2 0.0 10.3 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO26702.1 - 1.5e-08 34.8 13.3 0.062 13.6 0.0 8.0 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETO26702.1 - 2.9e-08 33.4 14.6 0.14 12.0 0.0 6.9 5 2 2 7 7 7 4 Tetratricopeptide repeat Atrophin-1 PF03154.10 ETO26702.1 - 0.018 13.2 2.0 0.029 12.5 1.4 1.2 1 0 0 1 1 1 0 Atrophin-1 family Ank_5 PF13857.1 ETO26702.1 - 0.12 12.6 0.0 0.12 12.6 0.0 3.4 3 0 0 3 3 2 0 Ankyrin repeats (many copies) Fis1_TPR_C PF14853.1 ETO26702.1 - 4.3 7.2 11.9 2.1 8.2 0.9 3.7 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat DUF4199 PF13858.1 ETO26703.1 - 0.0061 16.4 0.1 0.0075 16.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) ETRAMP PF09716.5 ETO26703.1 - 0.038 13.9 2.3 0.07 13.0 1.6 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Endonuclease_5 PF04493.9 ETO26703.1 - 0.067 12.5 0.3 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 Endonuclease V DUF4094 PF13334.1 ETO26703.1 - 0.083 13.2 0.3 0.14 12.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Ni_hydr_CYTB PF01292.15 ETO26703.1 - 0.084 12.2 0.0 0.095 12.0 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 BLVR PF06375.6 ETO26703.1 - 0.17 11.7 4.4 0.25 11.1 3.1 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) ETRAMP PF09716.5 ETO26704.1 - 0.85 9.6 3.1 22 5.0 2.1 2.8 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Secretin_N_2 PF07655.8 ETO26705.1 - 2.1 8.8 9.5 0.12 12.7 2.9 1.6 2 0 0 2 2 2 0 Secretin N-terminal domain Pkinase PF00069.20 ETO26706.1 - 5.7e-05 22.3 0.0 0.00012 21.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain PIP5K PF01504.13 ETO26707.1 - 0.015 14.4 3.5 0.019 14.0 2.4 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase YiiD_Cterm PF09500.5 ETO26707.1 - 0.15 11.6 1.8 0.81 9.2 0.1 2.0 2 0 0 2 2 2 0 Putative thioesterase (yiiD_Cterm) DUF912 PF06024.7 ETO26707.1 - 4.3 7.4 8.5 0.87 9.6 0.6 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) 7tm_1 PF00001.16 ETO26707.1 - 4.8 6.2 5.6 0.37 9.8 0.3 1.6 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) Sec62 PF03839.11 ETO26707.1 - 7.4 5.9 12.1 1.2 8.5 1.2 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 G-alpha PF00503.15 ETO26708.1 - 1.5e-27 96.3 0.4 1.5e-27 96.3 0.3 4.0 4 1 0 4 4 4 2 G-protein alpha subunit Arf PF00025.16 ETO26708.1 - 0.001 18.3 0.3 0.0029 16.8 0.2 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family TFIIA PF03153.8 ETO26708.1 - 1.5 8.6 44.5 0.05 13.5 22.2 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SOBP PF15279.1 ETO26709.1 - 0.15 12.3 4.2 0.19 12.1 2.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein SRP-alpha_N PF04086.8 ETO26709.1 - 0.56 9.5 25.1 0.75 9.1 17.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal FLO_LFY PF01698.11 ETO26709.1 - 1.1 8.0 18.3 1.4 7.6 12.7 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein CDC27 PF09507.5 ETO26709.1 - 1.1 8.3 29.0 1.6 7.8 20.1 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MIP-T3 PF10243.4 ETO26709.1 - 1.4 7.3 31.1 1.7 7.0 21.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PRKCSH-like PF12999.2 ETO26709.1 - 1.8 8.1 7.8 3.4 7.2 5.4 1.4 1 0 0 1 1 1 0 Glucosidase II beta subunit-like CR6_interact PF10147.4 ETO26710.1 - 0.0057 16.0 12.8 0.0076 15.5 8.9 1.3 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Transket_pyr PF02779.19 ETO26711.1 - 5.3e-29 100.9 0.0 6.4e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain UPF0060 PF02694.10 ETO26711.1 - 0.056 13.4 0.1 0.081 12.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised BCR, YnfA/UPF0060 family Plasmodium_Vir PF05795.6 ETO26711.1 - 0.093 11.9 0.7 0.12 11.5 0.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein MatE PF01554.13 ETO26713.1 - 4.5e-27 94.6 6.5 4.5e-27 94.6 4.5 3.0 3 0 0 3 3 3 1 MatE DUF1510 PF07423.6 ETO26713.1 - 0.0092 15.3 6.1 0.013 14.8 4.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Ycf1 PF05758.7 ETO26713.1 - 0.098 10.3 0.0 0.11 10.1 0.0 1.1 1 0 0 1 1 1 0 Ycf1 Myc_N PF01056.13 ETO26713.1 - 0.16 11.1 6.3 0.21 10.6 4.3 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Daxx PF03344.10 ETO26713.1 - 0.29 9.5 11.5 0.37 9.2 8.0 1.0 1 0 0 1 1 1 0 Daxx Family TRAP_alpha PF03896.11 ETO26713.1 - 0.56 9.1 5.5 0.85 8.5 3.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit MDM1 PF15501.1 ETO26713.1 - 0.71 8.7 9.1 0.93 8.3 6.3 1.0 1 0 0 1 1 1 0 Nuclear protein MDM1 Sporozoite_P67 PF05642.6 ETO26713.1 - 0.91 7.2 8.9 1.2 6.8 6.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen VID27 PF08553.5 ETO26713.1 - 2.7 6.1 9.4 3.5 5.7 6.5 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein TFIIF_alpha PF05793.7 ETO26713.1 - 5.9 5.1 15.8 7.7 4.7 10.9 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.9 ETO26713.1 - 6.2 4.7 10.5 8.5 4.2 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF877 PF05943.7 ETO26714.1 - 0.082 11.3 2.2 1.6 7.1 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF877) PAT1 PF09770.4 ETO26714.1 - 9.5 4.3 27.2 11 4.1 18.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SH3_1 PF00018.23 ETO26715.1 - 1.1e-12 47.1 0.2 1.8e-12 46.4 0.2 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 ETO26715.1 - 2.1e-11 43.2 0.2 3.5e-11 42.4 0.2 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 ETO26715.1 - 7e-06 25.4 0.0 1.2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 ETO26715.1 - 0.0012 18.9 0.5 0.0021 18.2 0.3 1.3 1 0 0 1 1 1 1 Bacterial SH3 domain DUF2277 PF10041.4 ETO26715.1 - 0.1 12.5 1.1 0.14 12.0 0.3 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2277) DUF2201_N PF13203.1 ETO26715.1 - 0.43 9.7 5.6 0.49 9.5 3.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Clathrin_lg_ch PF01086.12 ETO26716.1 - 1.5e-18 67.5 17.3 2e-18 67.1 12.0 1.2 1 0 0 1 1 1 1 Clathrin light chain DUF1389 PF07146.6 ETO26716.1 - 0.0045 16.0 3.8 0.0062 15.6 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1389) MSC PF09402.5 ETO26716.1 - 0.029 13.1 4.0 0.036 12.7 2.8 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Pox_A11 PF05061.8 ETO26716.1 - 0.054 12.5 1.6 0.064 12.3 1.1 1.2 1 0 0 1 1 1 0 Poxvirus A11 Protein DUSP PF06337.7 ETO26716.1 - 0.21 12.0 2.4 0.43 10.9 1.7 1.6 1 0 0 1 1 1 0 DUSP domain IncA PF04156.9 ETO26716.1 - 0.24 10.9 11.4 0.3 10.6 7.9 1.2 1 0 0 1 1 1 0 IncA protein DDHD PF02862.12 ETO26716.1 - 0.66 9.7 5.6 0.89 9.2 3.9 1.2 1 0 0 1 1 1 0 DDHD domain DUF2058 PF09831.4 ETO26716.1 - 4.3 7.1 19.2 0.85 9.4 10.9 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) Apolipoprotein PF01442.13 ETO26718.1 - 2.4e-05 23.9 23.5 0.00098 18.6 4.4 3.2 1 1 2 3 3 3 2 Apolipoprotein A1/A4/E domain Reo_sigmaC PF04582.7 ETO26718.1 - 0.01 15.0 0.2 0.01 15.0 0.2 2.8 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DUF725 PF05267.7 ETO26718.1 - 0.012 15.5 8.2 0.017 15.0 0.5 3.1 2 2 0 2 2 2 0 Protein of unknown function (DUF725) MCPsignal PF00015.16 ETO26718.1 - 0.049 13.1 20.3 0.42 10.1 2.4 3.2 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Vac_Fusion PF02346.11 ETO26718.1 - 0.091 12.1 9.5 11 5.4 0.1 4.5 4 1 0 4 4 4 0 Chordopoxvirus fusion protein DUF1664 PF07889.7 ETO26718.1 - 0.29 10.9 27.9 0.059 13.1 0.8 4.2 1 1 3 5 5 5 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 ETO26718.1 - 2.3 8.0 24.4 4.6 7.0 0.5 4.1 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1878 PF08963.5 ETO26719.1 - 0.029 14.5 0.9 0.12 12.6 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1878) U79_P34 PF03064.11 ETO26719.1 - 0.34 10.3 6.9 0.43 10.0 4.8 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF4211 PF13926.1 ETO26720.1 - 8.4e-05 22.0 3.7 0.32 10.4 0.1 3.5 1 1 1 3 3 3 3 Domain of unknown function (DUF4211) DUF826 PF05696.6 ETO26720.1 - 0.024 14.7 4.1 0.41 10.8 0.1 3.6 2 2 0 2 2 2 0 Protein of unknown function (DUF826) Cys_rich_VLP PF14194.1 ETO26721.1 - 0.1 12.3 2.1 0.12 12.0 0.1 2.0 2 0 0 2 2 2 0 Cysteine-rich VLP DUF1929 PF09118.6 ETO26723.1 - 3.6e-09 36.6 0.0 8.8e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Glyoxal_oxid_N PF07250.6 ETO26723.1 - 0.00017 20.7 0.2 0.66 8.9 0.1 4.0 3 1 0 3 3 3 2 Glyoxal oxidase N-terminus Kelch_6 PF13964.1 ETO26723.1 - 0.00029 20.8 3.1 0.17 12.1 0.0 5.4 6 0 0 6 6 6 1 Kelch motif Kelch_2 PF07646.10 ETO26723.1 - 0.0004 20.0 0.0 0.82 9.5 0.0 5.0 6 0 0 6 6 6 1 Kelch motif Kelch_4 PF13418.1 ETO26723.1 - 0.037 13.7 8.4 5.4 6.8 0.0 5.5 7 0 0 7 7 7 0 Galactose oxidase, central domain PNRC PF15365.1 ETO26723.1 - 0.089 12.8 0.4 0.33 11.0 0.3 2.0 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator WD40 PF00400.27 ETO26724.1 - 3.3e-73 239.1 21.1 4.4e-13 48.5 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO26724.1 - 2e-08 32.9 1.6 0.00062 18.1 0.1 2.7 1 1 2 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.3 ETO26724.1 - 2.4e-08 32.6 7.0 0.0004 18.6 1.7 3.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO26724.1 - 7.1e-07 28.9 0.3 5.3e-06 26.0 0.2 2.8 1 1 0 1 1 1 1 PQQ-like domain Nbas_N PF15492.1 ETO26724.1 - 2.4e-05 23.5 1.1 0.091 11.8 0.0 3.7 1 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 ETO26724.1 - 0.00017 21.1 7.9 3.7 7.3 0.0 5.2 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Pectate_lyase22 PF14583.1 ETO26724.1 - 0.0051 15.3 0.0 0.017 13.5 0.0 1.9 2 0 0 2 2 2 1 Oligogalacturonate lyase DUF1258 PF06869.7 ETO26724.1 - 0.048 12.7 6.0 0.54 9.3 0.2 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF1258) PQQ PF01011.16 ETO26724.1 - 0.071 12.6 0.0 2 8.0 0.0 3.3 5 0 0 5 5 5 0 PQQ enzyme repeat TFIIIC_delta PF12657.2 ETO26724.1 - 0.072 12.7 1.6 0.58 9.8 0.0 3.0 1 1 1 3 3 3 0 Transcription factor IIIC subunit delta N-term AzlD PF05437.7 ETO26725.1 - 0.1 12.5 5.5 0.03 14.2 1.4 1.8 2 0 0 2 2 2 0 Branched-chain amino acid transport protein (AzlD) Spc24 PF08286.6 ETO26726.1 - 0.012 15.2 3.7 0.012 15.2 2.5 5.9 2 1 2 5 5 5 0 Spc24 subunit of Ndc80 DUF1957 PF09210.6 ETO26726.1 - 0.037 14.0 6.3 0.061 13.3 0.6 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1957) DUF4530 PF15039.1 ETO26726.1 - 0.089 12.7 1.9 0.46 10.4 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) NYD-SP28_assoc PF14775.1 ETO26726.1 - 0.36 10.5 10.0 0.58 9.8 0.6 3.6 3 0 0 3 3 3 0 Sperm tail C-terminal domain DUF2746 PF10874.3 ETO26726.1 - 2.3 8.4 18.6 1.8 8.8 1.9 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2746) APG6 PF04111.7 ETO26726.1 - 7.4 5.5 52.4 0.02 13.9 3.3 3.4 2 1 0 3 3 3 0 Autophagy protein Apg6 SAM_1 PF00536.25 ETO26727.1 - 2.5e-18 66.0 0.2 3.2e-08 33.6 0.1 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO26727.1 - 2.1e-13 49.8 0.1 1.1e-06 28.3 0.0 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 ETO26727.1 - 0.00017 21.2 0.3 0.00061 19.4 0.1 2.0 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain WD40 PF00400.27 ETO26728.1 - 3.2e-49 163.1 15.5 1.5e-10 40.5 0.5 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO26728.1 - 7.9e-07 27.5 1.3 0.32 9.0 0.0 4.7 2 1 3 5 5 5 4 Nucleoporin Nup120/160 PAP_assoc PF03828.14 ETO26729.1 - 2.6e-11 43.3 0.4 2.4e-07 30.6 0.0 3.7 3 0 0 3 3 3 2 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 ETO26729.1 - 4.8e-06 26.8 0.0 1.6e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain YajC PF02699.10 ETO26729.1 - 0.096 12.3 1.4 0.19 11.4 0.9 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit Pkinase PF00069.20 ETO26730.1 - 7.5e-38 130.1 1.6 6e-34 117.3 0.1 2.5 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO26730.1 - 4.3e-25 88.2 0.0 4.8e-23 81.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 ETO26730.1 - 0.00036 20.3 0.0 0.00058 19.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 ETO26730.1 - 0.0044 16.0 0.0 0.066 12.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 ETO26730.1 - 0.013 14.5 1.0 0.024 13.7 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family HR1 PF02185.11 ETO26730.1 - 0.019 14.7 0.3 0.04 13.6 0.2 1.5 1 0 0 1 1 1 0 Hr1 repeat E1-E2_ATPase PF00122.15 ETO26732.1 - 1.1e-19 70.3 0.2 4.9e-19 68.2 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 ETO26732.1 - 5.4e-10 39.0 0.2 3.6e-09 36.4 0.0 2.4 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 ETO26732.1 - 3.2e-06 27.7 0.1 0.29 11.5 0.0 3.2 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETO26732.1 - 4.8e-05 23.6 0.1 0.48 10.5 0.0 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cytomega_UL20A PF05984.7 ETO26732.1 - 6.2 7.0 8.5 1.1 9.4 1.5 2.6 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein DUF1510 PF07423.6 ETO26733.1 - 0.0011 18.3 0.2 0.0014 18.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) RCR PF12273.3 ETO26733.1 - 0.0014 19.1 0.6 0.0023 18.4 0.4 1.4 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Peptidase_S49_N PF08496.5 ETO26733.1 - 0.0025 17.6 0.1 0.003 17.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S49 N-terminal DUF3552 PF12072.3 ETO26733.1 - 0.007 15.5 0.2 0.0087 15.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) EphA2_TM PF14575.1 ETO26733.1 - 0.012 15.9 1.3 0.023 15.0 0.9 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1628 PF07790.6 ETO26733.1 - 0.012 16.3 0.1 0.017 15.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1628) Shisa PF13908.1 ETO26733.1 - 0.015 15.5 0.0 0.019 15.1 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Neur_chan_memb PF02932.11 ETO26733.1 - 0.019 14.8 0.0 0.024 14.5 0.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4190 PF13828.1 ETO26733.1 - 0.021 14.3 0.1 0.04 13.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) WBP-1 PF11669.3 ETO26733.1 - 0.021 14.9 0.2 0.021 14.9 0.1 1.7 2 1 0 2 2 1 0 WW domain-binding protein 1 SpoIIIAH PF12685.2 ETO26733.1 - 0.026 14.0 0.1 0.032 13.7 0.1 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF4446 PF14584.1 ETO26733.1 - 0.036 13.9 0.3 0.045 13.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) FAM176 PF14851.1 ETO26733.1 - 0.047 13.3 0.0 0.064 12.9 0.0 1.1 1 0 0 1 1 1 0 FAM176 family Herpes_gE PF02480.11 ETO26733.1 - 0.053 11.7 0.0 0.065 11.4 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E MFS_Mycoplasma PF07672.8 ETO26733.1 - 0.059 12.5 0.1 0.076 12.1 0.1 1.1 1 0 0 1 1 1 0 Mycoplasma MFS transporter DUF929 PF06053.6 ETO26733.1 - 0.063 12.3 0.0 0.079 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF929) TMEM154 PF15102.1 ETO26733.1 - 0.064 12.9 0.8 0.14 11.8 0.5 1.7 1 1 0 1 1 1 0 TMEM154 protein family Trep_Strep PF09605.5 ETO26733.1 - 0.066 12.8 0.4 0.091 12.4 0.2 1.2 1 0 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF4097 PF13349.1 ETO26733.1 - 0.079 12.4 0.1 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) OSTbeta PF15048.1 ETO26733.1 - 0.12 12.4 0.1 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF1310 PF07006.6 ETO26733.1 - 0.35 10.3 3.9 2 7.9 2.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1310) DUF412 PF04217.8 ETO26734.1 - 0.21 11.3 5.4 5 6.9 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF412 WD40 PF00400.27 ETO26735.1 - 1.8e-78 255.8 20.2 5.7e-11 41.8 0.3 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 ETO26735.1 - 2.5e-08 32.5 16.1 0.74 7.8 0.0 6.8 1 1 6 7 7 7 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO26735.1 - 0.00039 19.2 9.3 1.4 7.5 0.1 5.3 1 1 5 6 6 6 2 Nup133 N terminal like DUF2527 PF10736.4 ETO26735.1 - 0.00062 19.3 0.5 0.66 9.6 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF2627) DUF3601 PF12208.3 ETO26735.1 - 0.0031 17.4 0.0 1.6 8.6 0.0 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF3601) Ricin_B_lectin PF00652.17 ETO26735.1 - 0.0072 16.3 0.3 0.5 10.3 0.0 2.9 2 2 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Gmad1 PF10647.4 ETO26735.1 - 0.0096 15.3 0.7 0.12 11.7 0.2 2.7 1 1 2 3 3 3 1 Lipoprotein LpqB beta-propeller domain Hira PF07569.6 ETO26735.1 - 0.012 14.8 1.6 6.4 5.9 0.0 4.1 1 1 3 5 5 5 0 TUP1-like enhancer of split DUF3732 PF12532.3 ETO26735.1 - 0.014 14.8 0.1 7 6.1 0.0 3.6 5 0 0 5 5 5 0 Protein of unknown function (DUF3732) Cytochrom_D1 PF02239.11 ETO26735.1 - 0.033 12.4 2.5 1.9 6.7 0.0 3.1 1 1 2 4 4 4 0 Cytochrome D1 heme domain PLD_C PF12357.3 ETO26735.1 - 0.044 13.3 0.3 45 3.6 0.0 4.3 5 0 0 5 5 5 0 Phospholipase D C terminal Resistin PF06954.6 ETO26735.1 - 0.16 12.2 0.3 9.8 6.5 0.0 3.2 2 1 1 3 3 3 0 Resistin Kelch_1 PF01344.20 ETO26737.1 - 0.00044 19.7 5.6 0.54 9.8 0.0 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 ETO26737.1 - 0.00046 20.2 6.4 6.1 7.2 0.2 5.8 5 1 1 6 6 6 2 Kelch motif DUF2663 PF10864.3 ETO26737.1 - 0.14 12.3 0.1 0.14 12.3 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2663) Kelch_4 PF13418.1 ETO26737.1 - 1 9.1 6.5 22 4.9 0.1 4.6 6 0 0 6 6 6 0 Galactose oxidase, central domain Pkinase PF00069.20 ETO26740.1 - 2.7e-64 216.8 0.0 5.5e-64 215.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO26740.1 - 2.8e-30 105.2 0.0 5.3e-30 104.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_6 PF13405.1 ETO26740.1 - 6.6e-14 50.4 1.6 8.5e-05 22.1 0.0 4.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 ETO26740.1 - 9.8e-13 48.0 9.1 1.6e-06 28.1 0.1 4.0 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 ETO26740.1 - 4.7e-12 44.2 18.9 1.3e-07 30.3 0.2 5.0 5 1 0 5 5 4 2 EF hand EF-hand_8 PF13833.1 ETO26740.1 - 1.4e-11 43.8 7.3 0.00017 21.1 0.4 4.2 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 ETO26740.1 - 3.5e-11 41.9 3.8 5.4e-06 25.5 0.1 4.1 3 0 0 3 3 3 2 EF hand APH PF01636.18 ETO26740.1 - 3.7e-06 26.8 0.0 3e-05 23.8 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 ETO26740.1 - 0.00052 19.4 0.6 0.00052 19.4 0.4 2.1 2 0 0 2 2 1 1 RIO1 family Choline_kinase PF01633.15 ETO26740.1 - 0.0015 18.1 0.8 0.0079 15.7 0.1 2.4 2 1 0 2 2 2 1 Choline/ethanolamine kinase EF-hand_4 PF12763.2 ETO26740.1 - 0.0017 18.0 0.6 0.39 10.4 0.0 2.9 3 0 0 3 3 2 1 Cytoskeletal-regulatory complex EF hand Pox_ser-thr_kin PF05445.6 ETO26740.1 - 0.0049 15.7 0.4 0.012 14.4 0.1 1.8 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 ETO26740.1 - 0.01 14.7 0.0 0.019 13.9 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 ETO26740.1 - 0.015 14.4 0.1 0.03 13.3 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DSHCT PF08148.7 ETO26740.1 - 0.051 12.8 0.0 0.16 11.1 0.0 1.8 1 0 0 1 1 1 0 DSHCT (NUC185) domain RNase_H2-Ydr279 PF09468.5 ETO26740.1 - 0.11 11.6 9.2 0.19 10.9 6.3 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) GAGA_bind PF06217.7 ETO26740.1 - 0.19 11.6 7.3 0.31 10.9 5.0 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Nucleoplasmin PF03066.10 ETO26740.1 - 0.44 10.0 13.7 0.75 9.2 9.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 ETO26740.1 - 2.6 5.9 15.1 4.3 5.2 10.4 1.3 1 0 0 1 1 1 0 CDC45-like protein YqfQ PF14181.1 ETO26740.1 - 2.7 8.0 16.5 5.1 7.1 11.5 1.4 1 0 0 1 1 1 0 YqfQ-like protein Tom37_C PF11801.3 ETO26740.1 - 3.9 7.2 8.1 2.9 7.7 3.8 1.9 2 0 0 2 2 2 0 Tom37 C-terminal domain RNA_pol_Rpc4 PF05132.9 ETO26740.1 - 6.8 6.6 11.6 14 5.6 8.0 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Caldesmon PF02029.10 ETO26741.1 - 0.014 13.8 1.2 0.019 13.4 0.8 1.2 1 0 0 1 1 1 0 Caldesmon tRNA_anti-codon PF01336.20 ETO26742.1 - 5.8e-12 45.2 0.6 8.5e-07 28.7 0.0 2.8 2 1 0 2 2 2 2 OB-fold nucleic acid binding domain Rep-A_N PF04057.7 ETO26742.1 - 1.2e-05 25.0 0.2 5.8e-05 22.8 0.1 2.1 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain DUF223 PF02721.9 ETO26742.1 - 0.046 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF223 DUF4635 PF15466.1 ETO26742.1 - 0.063 12.5 0.2 0.16 11.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) Utp14 PF04615.8 ETO26744.1 - 0.12 10.5 34.2 0.15 10.1 23.7 1.1 1 0 0 1 1 1 0 Utp14 protein SMC_N PF02463.14 ETO26745.1 - 9.4e-33 113.2 13.2 1.9e-28 99.2 0.0 3.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 ETO26745.1 - 2.8e-10 40.8 39.8 2e-07 31.5 27.6 3.1 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.1 ETO26745.1 - 8e-07 29.2 0.1 8e-07 29.2 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 ETO26745.1 - 1.8e-05 24.1 0.0 4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 ETO26745.1 - 0.051 13.8 0.2 0.051 13.8 0.1 3.0 2 2 0 2 2 2 0 ABC transporter AAA_17 PF13207.1 ETO26745.1 - 0.53 11.1 3.2 1.4 9.7 0.0 2.8 2 1 0 2 2 2 0 AAA domain SMC_N PF02463.14 ETO26746.1 - 4.1e-23 81.7 16.2 4.1e-23 81.7 11.2 2.2 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 ETO26746.1 - 1.2e-22 80.1 0.6 2.9e-22 78.8 0.4 1.7 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain Phage_lysis PF03245.8 ETO26746.1 - 0.0013 18.7 7.6 0.0013 18.7 5.3 4.9 3 2 1 4 4 4 1 Bacteriophage Rz lysis protein AAA_13 PF13166.1 ETO26746.1 - 0.0016 17.0 39.3 0.0016 17.0 27.3 3.7 2 1 1 3 3 3 3 AAA domain Reo_sigmaC PF04582.7 ETO26746.1 - 0.56 9.3 21.1 0.2 10.7 1.5 3.1 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Spc7 PF08317.6 ETO26746.1 - 1.1 7.8 83.2 0.076 11.6 8.6 4.6 3 1 1 4 4 4 0 Spc7 kinetochore protein IncA PF04156.9 ETO26746.1 - 1.7 8.2 86.5 0.19 11.3 12.1 5.3 2 2 3 5 5 5 0 IncA protein ADIP PF11559.3 ETO26747.1 - 0.0041 17.0 27.4 0.018 14.9 7.5 2.3 2 0 0 2 2 2 2 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 ETO26747.1 - 0.012 15.9 6.2 0.012 15.9 4.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF972) HALZ PF02183.13 ETO26747.1 - 0.02 14.6 4.2 0.02 14.6 2.9 3.2 3 1 1 4 4 4 0 Homeobox associated leucine zipper LT-IIB PF06453.6 ETO26747.1 - 0.053 13.1 0.1 0.4 10.3 0.1 2.1 2 0 0 2 2 2 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) Nup54 PF13874.1 ETO26747.1 - 0.065 12.8 18.1 0.029 14.0 4.8 2.2 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 GAS PF13851.1 ETO26747.1 - 0.068 12.3 25.5 0.11 11.6 9.1 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CCDC155 PF14662.1 ETO26747.1 - 0.073 12.6 22.1 0.03 13.9 5.3 2.4 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 Lectin_N PF03954.9 ETO26747.1 - 0.16 11.3 7.0 0.068 12.5 0.8 2.2 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Phage_glycop_gL PF11108.3 ETO26747.1 - 0.44 10.5 5.8 0.66 9.9 0.2 2.6 2 2 0 2 2 2 0 Viral glycoprotein L DUF1664 PF07889.7 ETO26747.1 - 0.93 9.3 8.1 0.29 10.9 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.3 ETO26747.1 - 2.2 8.0 27.1 0.085 12.5 2.8 3.2 1 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding TLE_N PF03920.10 ETO26747.1 - 2.2 8.1 10.4 6.7 6.5 2.2 2.4 2 0 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain PEARLI-4 PF05278.7 ETO26747.1 - 3.8 6.7 16.2 0.42 9.9 5.9 2.1 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) EAP30 PF04157.11 ETO26747.1 - 4.3 6.4 13.1 4.2 6.4 2.5 2.2 2 0 0 2 2 2 0 EAP30/Vps36 family PspA_IM30 PF04012.7 ETO26747.1 - 6.6 6.0 15.9 1.1e+02 2.0 11.1 2.1 1 1 0 1 1 1 0 PspA/IM30 family DUF948 PF06103.6 ETO26747.1 - 8.8 6.2 9.3 9.4 6.1 0.8 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Sec8_exocyst PF04048.9 ETO26748.1 - 0.099 12.2 6.5 2.9 7.5 1.2 2.4 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Erf4 PF10256.4 ETO26748.1 - 2.4 8.0 9.2 1.1 9.1 4.5 1.8 2 1 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family EF-hand_7 PF13499.1 ETO26749.1 - 0.00027 21.0 0.5 0.013 15.5 0.0 2.5 2 1 0 2 2 2 1 EF-hand domain pair BRCT PF00533.21 ETO26749.1 - 0.0083 16.2 0.1 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain EF-hand_1 PF00036.27 ETO26749.1 - 0.011 14.9 0.1 0.033 13.4 0.0 1.8 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 ETO26749.1 - 0.05 13.4 0.3 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain EF-hand_6 PF13405.1 ETO26750.1 - 0.064 13.1 0.2 0.22 11.4 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain FAD_binding_3 PF01494.14 ETO26752.1 - 1.5e-05 24.2 0.1 2.3e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DUF4312 PF14189.1 ETO26752.1 - 0.048 13.4 1.6 0.37 10.6 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4312) TRM13 PF05206.9 ETO26753.1 - 1e-25 90.4 6.8 1e-25 90.4 4.7 2.5 1 1 2 3 3 3 1 Methyltransferase TRM13 Phe_ZIP PF08916.6 ETO26753.1 - 0.085 13.1 0.1 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 Phenylalanine zipper SAC3_GANP PF03399.11 ETO26754.1 - 1.4e-06 27.9 1.1 1.8e-06 27.6 0.7 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Hormone_1 PF00103.15 ETO26754.1 - 0.041 13.2 1.6 0.14 11.4 0.3 2.0 2 0 0 2 2 2 0 Somatotropin hormone family CorA PF01544.13 ETO26754.1 - 0.044 12.7 0.2 0.062 12.3 0.1 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Glyco_hydro_47 PF01532.15 ETO26755.1 - 2.2e-58 198.0 4.8 2.8e-58 197.6 3.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Dicty_REP PF05086.7 ETO26757.1 - 0.0019 16.0 9.9 0.0019 16.0 6.8 1.5 2 0 0 2 2 2 1 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 ETO26757.1 - 0.91 9.2 10.4 0.46 10.2 5.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) TMF_DNA_bd PF12329.3 ETO26761.1 - 0.0019 17.9 6.2 0.0019 17.9 4.3 4.3 3 1 1 4 4 4 1 TATA element modulatory factor 1 DNA binding RuvC PF02075.12 ETO26761.1 - 0.086 12.6 0.5 3.6 7.4 0.0 3.0 3 0 0 3 3 3 0 Crossover junction endodeoxyribonuclease RuvC EF-hand_4 PF12763.2 ETO26762.1 - 3.9e-09 36.1 1.1 3.9e-07 29.7 0.1 3.1 3 0 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand DUF3491 PF11996.3 ETO26763.1 - 0.032 11.7 0.0 0.04 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3491) Peptidase_S49_N PF08496.5 ETO26764.1 - 0.42 10.3 4.1 0.15 11.8 0.4 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal HORMA PF02301.13 ETO26765.1 - 0.015 14.7 0.8 0.022 14.2 0.5 1.2 1 0 0 1 1 1 0 HORMA domain TBPIP PF07106.8 ETO26766.1 - 0.0016 17.9 4.1 0.0016 17.9 2.9 2.2 2 0 0 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF327 PF03885.8 ETO26766.1 - 0.018 14.8 0.3 0.018 14.8 0.2 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF327) Bcr-Abl_Oligo PF09036.5 ETO26766.1 - 0.028 14.3 1.5 2.3 8.2 0.1 2.4 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Latarcin PF10279.4 ETO26766.1 - 0.36 11.0 7.6 1.7 8.9 5.2 2.2 1 1 0 1 1 1 0 Latarcin precursor FlaC_arch PF05377.6 ETO26766.1 - 2.2 8.2 6.7 0.9 9.4 0.6 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Ribonuc_red_lgC PF02867.10 ETO26767.1 - 5.1e-174 579.7 0.2 9.2e-122 407.3 0.0 3.6 3 1 0 3 3 3 3 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 ETO26767.1 - 5.4e-24 83.7 0.0 1.2e-23 82.6 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 ETO26767.1 - 9.1e-11 42.0 0.0 4.6e-10 39.8 0.0 2.2 2 0 0 2 2 2 1 ATP cone domain Rad60-SLD PF11976.3 ETO26768.1 - 1.2e-24 85.7 0.1 1.5e-24 85.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 ETO26768.1 - 1.3e-07 30.8 0.1 1.8e-07 30.4 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family Sec31 PF11549.3 ETO26768.1 - 0.54 9.9 5.4 0.47 10.1 2.6 1.8 1 1 1 2 2 2 0 Protein transport protein SEC31 ELFV_dehydrog PF00208.16 ETO26769.1 - 2.5e-53 181.1 0.1 3.2e-53 180.8 0.1 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 ETO26769.1 - 2.3e-29 101.6 0.0 4.6e-29 100.6 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain AlaDh_PNT_C PF01262.16 ETO26769.1 - 0.0023 17.5 0.0 0.0039 16.7 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 ETO26769.1 - 0.011 14.9 0.1 0.018 14.2 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 ETO26769.1 - 0.011 15.9 0.1 0.021 15.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Semialdhyde_dh PF01118.19 ETO26769.1 - 0.036 14.3 0.0 1.9 8.7 0.0 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain FimP PF09766.4 ETO26770.1 - 1.5 7.7 17.1 2.8 6.9 2.5 2.2 2 0 0 2 2 2 0 Fms-interacting protein PKD_channel PF08016.7 ETO26771.1 - 0.0055 15.1 0.3 0.01 14.3 0.2 1.4 1 0 0 1 1 1 1 Polycystin cation channel Merozoite_SPAM PF07133.6 ETO26773.1 - 0.011 15.6 6.9 0.014 15.2 4.8 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Gcd10p PF04189.8 ETO26773.1 - 0.011 14.8 1.6 0.017 14.3 1.1 1.2 1 0 0 1 1 1 0 Gcd10p family DUF1682 PF07946.9 ETO26773.1 - 0.045 12.5 2.5 0.055 12.3 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Peptidase_S49_N PF08496.5 ETO26773.1 - 0.086 12.6 0.7 0.12 12.1 0.5 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Mago_nashi PF02792.9 ETO26773.1 - 0.091 12.4 0.9 0.12 12.0 0.6 1.2 1 0 0 1 1 1 0 Mago nashi protein SAE2 PF08573.5 ETO26773.1 - 0.39 11.4 4.4 0.64 10.7 3.0 1.4 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Wound_ind PF08186.6 ETO26773.1 - 0.83 9.6 5.0 1.3 8.9 3.5 1.3 1 0 0 1 1 1 0 Wound-inducible basic protein family Folliculin PF11704.3 ETO26773.1 - 3.3 7.2 5.3 3.2 7.3 2.5 1.7 1 1 1 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Myb_DNA-bind_3 PF12776.2 ETO26774.1 - 0.42 11.2 3.5 14 6.3 0.0 3.5 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain Hydant_A_N PF05378.8 ETO26775.1 - 0.041 13.4 0.3 0.073 12.5 0.0 1.6 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase N-terminal region PDEase_I PF00233.14 ETO26776.1 - 3.5e-24 85.8 0.0 7e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF4661 PF15576.1 ETO26776.1 - 8.5 5.9 10.0 11 5.5 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Host_attach PF10116.4 ETO26777.1 - 0.01 16.0 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 Protein required for attachment to host cells DUF4251 PF14059.1 ETO26777.1 - 0.014 15.2 1.7 0.023 14.5 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4251) DUF2413 PF10310.4 ETO26777.1 - 0.076 11.8 1.3 0.12 11.1 0.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2413) Plasmodium_Vir PF05795.6 ETO26777.1 - 0.2 10.8 4.2 0.28 10.3 2.9 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF3451 PF11933.3 ETO26777.1 - 0.47 10.2 5.6 0.23 11.2 2.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3451) SART-1 PF03343.8 ETO26777.1 - 1.4 7.1 8.0 2.6 6.2 5.6 1.4 1 0 0 1 1 1 0 SART-1 family NST1 PF13945.1 ETO26777.1 - 3.4 7.6 12.1 0.84 9.6 5.7 1.9 2 0 0 2 2 2 0 Salt tolerance down-regulator PCEMA1 PF07418.6 ETO26778.1 - 0.69 9.2 44.7 0.21 10.9 19.0 2.1 2 0 0 2 2 2 0 Acidic phosphoprotein precursor PCEMA1 DUF2457 PF10446.4 ETO26780.1 - 0.012 14.3 6.1 0.032 12.9 4.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ctr PF04145.10 ETO26780.1 - 0.026 14.5 8.0 0.25 11.3 0.1 3.3 3 1 0 3 3 3 0 Ctr copper transporter family HEAT PF02985.17 ETO26780.1 - 0.035 14.1 0.7 60 4.1 0.0 4.1 3 1 1 4 4 4 0 HEAT repeat Zip PF02535.17 ETO26780.1 - 0.67 8.9 6.4 0.86 8.5 0.1 2.8 2 1 0 2 2 2 0 ZIP Zinc transporter SPX PF03105.14 ETO26780.1 - 6.2 6.5 28.7 0.63 9.7 11.5 3.0 3 0 0 3 3 3 0 SPX domain Neisseria_TspB PF05616.8 ETO26781.1 - 0.00089 17.7 0.0 0.00098 17.6 0.0 1.1 1 0 0 1 1 1 1 Neisseria meningitidis TspB protein Cyclin_N PF00134.18 ETO26782.1 - 6.9e-33 112.9 1.9 2.1e-32 111.3 1.3 1.9 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 ETO26782.1 - 7.2e-15 54.9 5.3 7.4e-14 51.6 3.7 2.4 1 1 0 1 1 1 1 Cyclin, C-terminal domain DUF3671 PF12420.3 ETO26782.1 - 3.9 7.5 14.0 3.6 7.6 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function KTI12 PF08433.5 ETO26783.1 - 6.3e-07 28.8 1.0 7.7e-07 28.5 0.7 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 ETO26783.1 - 0.0014 18.5 0.0 0.0048 16.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain Viral_Hsp90 PF03225.9 ETO26783.1 - 0.004 15.5 1.1 0.005 15.1 0.8 1.3 1 0 0 1 1 1 1 Viral heat shock protein Hsp90 homologue Imm16 PF15565.1 ETO26783.1 - 0.11 12.3 0.6 0.39 10.5 0.3 2.0 1 1 1 2 2 2 0 Immunity protein 16 Annexin PF00191.15 ETO26784.1 - 0.0006 19.6 0.1 0.0006 19.6 0.1 3.0 4 0 0 4 4 4 1 Annexin IncA PF04156.9 ETO26784.1 - 1.2 8.7 62.5 0.066 12.7 13.4 4.2 1 1 3 4 4 4 0 IncA protein DUF812 PF05667.6 ETO26784.1 - 9.2 4.6 64.4 0.033 12.7 22.8 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF812) Eapp_C PF10238.4 ETO26785.1 - 0.11 12.3 13.8 0.23 11.3 4.2 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein POX PF07526.6 ETO26785.1 - 0.84 9.8 5.2 3.9 7.7 0.7 2.3 2 0 0 2 2 2 0 Associated with HOX Pkinase_Tyr PF07714.12 ETO26786.1 - 1.4e-24 86.5 0.9 2.5e-24 85.7 0.6 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 ETO26786.1 - 5.7e-24 84.6 1.5 5.7e-24 84.6 1.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.1 ETO26786.1 - 0.00051 19.0 0.0 0.00096 18.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Menin PF05053.8 ETO26786.1 - 0.0041 15.3 8.6 0.007 14.5 5.9 1.3 1 0 0 1 1 1 1 Menin DUF2457 PF10446.4 ETO26786.1 - 0.074 11.7 11.7 0.11 11.1 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DctQ PF04290.7 ETO26786.1 - 5.5 6.7 20.9 0.15 11.8 5.0 2.4 1 1 1 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Sporozoite_P67 PF05642.6 ETO26786.1 - 6.2 4.5 16.5 9.4 3.9 11.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cupin_2 PF07883.6 ETO26787.1 - 3.7e-11 42.3 0.1 9.3e-11 41.0 0.1 1.6 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 ETO26787.1 - 3.4e-07 29.8 0.0 3.9e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Cupin FdtA PF05523.6 ETO26787.1 - 0.0022 17.4 0.1 0.0038 16.7 0.1 1.3 1 0 0 1 1 1 1 WxcM-like, C-terminal Cupin_8 PF13621.1 ETO26787.1 - 0.0084 15.6 1.3 0.024 14.1 0.9 1.7 1 1 0 1 1 1 1 Cupin-like domain Ectoine_synth PF06339.7 ETO26787.1 - 0.037 13.9 0.1 0.05 13.5 0.1 1.3 1 0 0 1 1 1 0 Ectoine synthase SUKH_5 PF14567.1 ETO26787.1 - 0.038 13.4 0.0 0.07 12.5 0.0 1.4 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall DASH_Dam1 PF08653.5 ETO26788.1 - 0.093 12.5 1.9 0.49 10.1 0.2 2.6 2 0 0 2 2 2 0 DASH complex subunit Dam1 DUF1411 PF07199.6 ETO26788.1 - 0.11 11.9 3.5 0.057 12.8 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1411) GN3L_Grn1 PF08701.6 ETO26789.1 - 0.014 15.2 0.9 0.014 15.2 0.6 2.4 2 0 0 2 2 2 0 GNL3L/Grn1 putative GTPase PAT1 PF09770.4 ETO26789.1 - 0.15 10.3 34.7 0.17 10.1 24.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 ETO26789.1 - 0.19 9.8 39.9 0.2 9.8 27.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 ETO26789.1 - 4.3 7.1 26.3 5.1 6.8 18.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4199 PF13858.1 ETO26790.1 - 0.039 13.8 0.0 0.096 12.5 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) Methyltransf_16 PF10294.4 ETO26791.1 - 9.2e-16 57.7 6.1 2.6e-14 53.0 4.2 2.4 1 1 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 ETO26791.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PTS_2-RNA PF01885.11 ETO26792.1 - 1.1e-27 96.5 0.2 1.5e-27 96.0 0.1 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Neil1-DNA_bind PF09292.5 ETO26792.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Endonuclease VIII-like 1, DNA bind Pkinase PF00069.20 ETO26793.1 - 4.6e-24 84.9 5.8 8.4e-23 80.8 4.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO26793.1 - 2.2e-06 26.9 4.6 9.4e-06 24.8 3.2 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO26793.1 - 0.0006 18.9 0.8 0.0012 17.9 0.6 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO26793.1 - 0.017 14.8 0.0 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family MDFI PF15316.1 ETO26793.1 - 0.29 11.1 1.8 12 5.8 0.0 2.4 2 0 0 2 2 2 0 MyoD family inhibitor Ribosomal_L24e PF01246.15 ETO26793.1 - 0.54 10.1 7.0 1.3 8.9 4.9 1.7 1 0 0 1 1 1 0 Ribosomal protein L24e IPK PF03770.11 ETO26793.1 - 5.2 6.6 9.6 40 3.7 6.7 2.2 1 1 0 1 1 1 0 Inositol polyphosphate kinase BTB PF00651.26 ETO26794.1 - 0.00083 19.3 0.2 0.48 10.4 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain Skp1 PF01466.14 ETO26794.1 - 3.7 7.6 8.1 3.4 7.7 0.1 3.7 4 0 0 4 4 4 0 Skp1 family, dimerisation domain Pkinase PF00069.20 ETO26796.1 - 1.9e-17 63.2 0.0 2.9e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO26796.1 - 0.00016 20.8 0.0 0.00023 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 ETO26797.1 - 3.5e-26 91.9 0.2 5e-26 91.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO26797.1 - 3.2e-10 39.5 0.2 5.2e-10 38.8 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.14 ETO26797.1 - 0.00051 20.1 0.1 0.0016 18.4 0.0 1.8 1 1 1 2 2 2 1 Regulator of G protein signaling domain SPT6_acidic PF14632.1 ETO26797.1 - 0.16 12.1 0.8 0.32 11.1 0.5 1.5 1 0 0 1 1 1 0 Acidic N-terminal SPT6 zf-C2H2_4 PF13894.1 ETO26798.1 - 0.0088 16.3 20.7 2 8.9 0.2 6.2 6 1 0 6 6 6 3 C2H2-type zinc finger Rubredoxin PF00301.15 ETO26798.1 - 1.2 9.0 8.0 5.8 6.8 0.5 4.1 4 0 0 4 4 4 0 Rubredoxin Sgf11 PF08209.6 ETO26798.1 - 3 7.2 14.2 9.1 5.6 0.8 4.7 4 1 0 4 4 4 0 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 ETO26798.1 - 6.2 6.6 9.9 2.4 7.9 0.0 4.3 4 0 0 4 4 4 0 zinc-finger of a C2HC-type WD40 PF00400.27 ETO26799.1 - 1.9e-80 262.1 20.6 2.4e-12 46.2 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO26799.1 - 3.6e-06 25.5 0.2 5.2e-05 21.7 0.1 2.4 1 1 1 2 2 2 1 Cytochrome D1 heme domain Nup160 PF11715.3 ETO26799.1 - 5.8e-06 24.7 5.1 0.88 7.6 0.0 4.5 1 1 2 4 4 4 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO26799.1 - 9.9e-05 21.9 0.6 0.81 9.0 0.0 3.3 2 1 1 3 3 3 1 PQQ-like domain Nbas_N PF15492.1 ETO26799.1 - 0.00012 21.2 1.3 2.3 7.2 0.0 3.8 1 1 3 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 ETO26799.1 - 0.00017 21.1 2.9 1.5 8.5 0.1 4.1 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO26799.1 - 0.00041 20.5 5.7 1.3 9.3 0.1 3.8 2 2 1 3 3 3 1 Resistin DPPIV_N PF00930.16 ETO26799.1 - 0.0012 17.5 0.1 0.98 7.9 0.0 3.6 1 1 2 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Tox-PL PF15644.1 ETO26799.1 - 0.023 15.4 0.1 6.9 7.4 0.0 2.9 2 0 0 2 2 2 0 Papain fold toxin 1 BBS2_Mid PF14783.1 ETO26799.1 - 0.033 13.9 1.0 6.2 6.6 0.0 4.3 2 2 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region DUF3913 PF13052.1 ETO26799.1 - 0.039 13.9 0.1 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3913) PLD_C PF12357.3 ETO26799.1 - 0.079 12.5 0.1 10 5.7 0.0 3.9 5 0 0 5 5 5 0 Phospholipase D C terminal Proteasome_A_N PF10584.4 ETO26799.1 - 1.8 7.9 5.8 66 2.9 0.0 4.3 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature MTHFR PF02219.12 ETO26800.1 - 1.4e-90 303.2 0.0 9.6e-90 300.5 0.0 2.2 1 1 0 1 1 1 1 Methylenetetrahydrofolate reductase PPR_2 PF13041.1 ETO26801.1 - 0.00014 21.7 1.5 0.0034 17.3 0.4 2.9 2 1 1 3 3 3 1 PPR repeat family WD40 PF00400.27 ETO26805.1 - 5.4e-34 114.8 12.7 4e-11 42.3 1.4 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO26805.1 - 5.1e-09 34.8 3.0 0.00031 19.0 0.3 3.0 2 1 0 3 3 3 3 Nucleoporin Nup120/160 HARP PF07443.8 ETO26805.1 - 0.087 12.2 1.1 4.2 6.8 0.1 2.6 3 0 0 3 3 3 0 HepA-related protein (HARP) WD40 PF00400.27 ETO26806.1 - 4.6e-11 42.1 0.4 6.6e-10 38.4 0.0 2.7 3 0 0 3 3 3 1 WD domain, G-beta repeat Ank_4 PF13637.1 ETO26807.1 - 0.0013 19.2 0.0 0.0038 17.6 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO26807.1 - 0.0014 18.9 0.2 0.0052 17.0 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Methyltransf_11 PF08241.7 ETO26807.1 - 0.0097 16.3 0.4 0.033 14.6 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ank_3 PF13606.1 ETO26807.1 - 0.033 14.4 0.0 1.2 9.5 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat UCH PF00443.24 ETO26808.1 - 7.7e-25 87.5 1.0 1.3e-24 86.7 0.7 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO26808.1 - 4.2e-10 39.5 12.9 3.1e-09 36.7 8.9 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Mito_fiss_reg PF05308.6 ETO26808.1 - 0.0047 16.3 2.0 0.0047 16.3 1.4 1.9 2 0 0 2 2 2 1 Mitochondrial fission regulator LMBR1 PF04791.11 ETO26808.1 - 5 5.5 6.1 7 5.1 4.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein TMF_TATA_bd PF12325.3 ETO26809.1 - 0.0037 16.9 15.4 0.0037 16.9 10.7 9.0 7 1 1 9 9 9 1 TATA element modulatory factor 1 TATA binding bZIP_1 PF00170.16 ETO26809.1 - 0.021 14.7 0.7 0.021 14.7 0.5 8.6 10 2 2 12 12 12 0 bZIP transcription factor CAP_GLY PF01302.20 ETO26811.1 - 3.5e-11 42.6 2.0 3.5e-11 42.6 1.4 2.0 2 0 0 2 2 2 1 CAP-Gly domain Apis_Csd PF11671.3 ETO26811.1 - 7.3 6.3 11.2 11 5.8 7.4 1.5 1 1 0 1 1 1 0 Complementary sex determiner protein Ctr PF04145.10 ETO26812.1 - 1.6e-05 24.9 3.9 3.4e-05 23.9 2.7 1.5 1 0 0 1 1 1 1 Ctr copper transporter family Daxx PF03344.10 ETO26814.1 - 0.31 9.4 38.6 0.37 9.2 26.8 1.1 1 0 0 1 1 1 0 Daxx Family TFIIF_alpha PF05793.7 ETO26814.1 - 0.96 7.7 48.4 1.2 7.3 33.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF572 PF04502.8 ETO26814.1 - 3.3 6.8 38.4 5 6.2 26.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) RVT_1 PF00078.22 ETO26815.1 - 5.3e-20 71.6 0.0 1.8e-19 69.9 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) NUT_N PF12881.2 ETO26816.1 - 0.081 12.0 0.1 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 NUT protein N terminus bZIP_1 PF00170.16 ETO26817.1 - 0.043 13.7 5.0 1.2 9.0 1.0 2.3 2 0 0 2 2 2 0 bZIP transcription factor DUF904 PF06005.7 ETO26817.1 - 0.055 13.7 10.2 0.73 10.1 3.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF904) ATG16 PF08614.6 ETO26817.1 - 0.082 12.7 10.8 2.3 7.9 0.2 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Herpes_BLRF2 PF05812.7 ETO26817.1 - 0.15 11.8 5.5 0.28 11.0 1.3 2.2 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein DUF3573 PF12097.3 ETO26817.1 - 0.15 10.6 3.7 0.2 10.2 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF972 PF06156.8 ETO26817.1 - 0.39 11.0 8.1 1.4 9.2 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TSC22 PF01166.13 ETO26817.1 - 2.3 8.2 5.0 8.8 6.3 0.1 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family bZIP_2 PF07716.10 ETO26817.1 - 5.6 6.8 6.6 1.3 8.9 1.8 2.0 2 0 0 2 2 2 0 Basic region leucine zipper DivIC PF04977.10 ETO26817.1 - 7.8 6.0 9.2 14 5.2 2.8 2.3 2 0 0 2 2 2 0 Septum formation initiator Kelch_6 PF13964.1 ETO26818.1 - 2.1e-05 24.4 0.9 3.8e-05 23.6 0.6 1.4 1 0 0 1 1 1 1 Kelch motif Kelch_1 PF01344.20 ETO26818.1 - 0.00013 21.4 1.4 0.00022 20.6 0.9 1.4 1 0 0 1 1 1 1 Kelch motif Kelch_4 PF13418.1 ETO26818.1 - 0.0013 18.4 0.2 0.0022 17.7 0.1 1.3 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO26818.1 - 0.0038 17.3 0.1 0.0059 16.7 0.1 1.3 1 0 0 1 1 1 1 Galactose oxidase, central domain DUF4252 PF14060.1 ETO26818.1 - 0.014 14.9 0.3 0.032 13.7 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4252) F5_F8_type_C PF00754.20 ETO26818.1 - 0.042 13.6 0.4 0.049 13.4 0.3 1.1 1 0 0 1 1 1 0 F5/8 type C domain DUF3789 PF12664.2 ETO26818.1 - 0.087 12.1 1.8 0.19 11.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3789) Kelch_5 PF13854.1 ETO26818.1 - 0.23 11.4 4.4 0.56 10.2 3.0 1.7 1 0 0 1 1 1 0 Kelch motif PIG-S PF10510.4 ETO26819.1 - 3e-50 171.3 1.3 3.7e-50 171.0 0.9 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein GnsAB PF08178.6 ETO26819.1 - 0.039 13.5 0.5 0.1 12.2 0.3 1.6 1 0 0 1 1 1 0 GnsA/GnsB family BatD PF13584.1 ETO26820.1 - 0.14 10.6 0.2 5.9 5.3 0.0 2.1 2 0 0 2 2 2 0 Oxygen tolerance DUF1516 PF07457.6 ETO26820.1 - 0.27 11.3 2.8 20 5.2 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1516) FtsX PF02687.16 ETO26820.1 - 0.95 9.2 7.0 0.19 11.4 0.2 2.3 1 1 1 2 2 2 0 FtsX-like permease family DctQ PF04290.7 ETO26820.1 - 1.8 8.3 8.0 1.5 8.6 0.9 2.9 2 1 2 4 4 4 0 Tripartite ATP-independent periplasmic transporters, DctQ component FA_desaturase PF00487.19 ETO26820.1 - 2.2 7.6 7.5 5.5 6.3 1.4 2.3 1 1 1 2 2 2 0 Fatty acid desaturase DUF805 PF05656.9 ETO26820.1 - 3.9 7.3 9.2 14 5.5 2.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF805) DUF1935 PF09149.5 ETO26822.1 - 0.073 13.0 0.7 0.23 11.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1935) eIF-6 PF01912.13 ETO26823.1 - 2.5e-79 265.0 1.0 4.7e-79 264.1 0.7 1.4 1 0 0 1 1 1 1 eIF-6 family FtsX PF02687.16 ETO26823.1 - 1.1e-23 83.2 38.5 2.2e-14 53.2 7.6 4.5 5 1 0 5 5 5 2 FtsX-like permease family Nucleotid_trans PF03407.11 ETO26825.1 - 1.3e-06 28.3 0.4 3.7e-06 26.8 0.2 1.7 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase ERG4_ERG24 PF01222.12 ETO26826.1 - 4e-58 196.9 29.6 4.7e-58 196.7 20.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family S6PP PF05116.8 ETO26827.1 - 1.2e-33 116.4 1.4 4.8e-20 71.8 0.0 2.9 3 0 0 3 3 3 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.7 ETO26827.1 - 2.2e-09 37.2 0.0 7e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETO26827.1 - 0.0092 16.1 0.0 0.015 15.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase AA_permease PF00324.16 ETO26828.1 - 3e-17 62.1 14.3 5.8e-13 48.0 5.9 2.1 1 1 1 2 2 2 2 Amino acid permease Cation_ATPase_N PF00690.21 ETO26828.1 - 0.12 11.8 0.1 0.4 10.1 0.1 1.9 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus Pkinase PF00069.20 ETO26829.1 - 1.3e-05 24.4 0.0 1.7e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIH_assoc PF08454.6 ETO26829.1 - 0.056 13.0 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 RyR and IP3R Homology associated Cas_Cmr3 PF09700.5 ETO26829.1 - 0.11 11.9 0.0 0.14 11.5 0.0 1.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr3) Nucleocapsid-N PF11030.3 ETO26831.1 - 0.11 12.2 0.4 0.11 12.2 0.3 1.1 1 0 0 1 1 1 0 Nucleocapsid protein N CAP_GLY PF01302.20 ETO26832.1 - 4.9e-52 173.5 11.8 1.4e-20 72.7 0.1 3.3 3 0 0 3 3 3 3 CAP-Gly domain EF-hand_1 PF00036.27 ETO26832.1 - 1.9e-10 39.2 0.1 2.2e-05 23.4 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 ETO26832.1 - 5.4e-09 36.0 0.0 2.1e-08 34.1 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO26832.1 - 2.1e-07 30.2 0.1 0.0038 16.9 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 ETO26832.1 - 9.3e-07 28.3 0.0 0.0045 16.5 0.0 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 ETO26832.1 - 6e-06 25.3 0.1 0.0032 16.7 0.0 2.7 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.4 ETO26832.1 - 2.4e-05 24.3 0.1 2.4e-05 24.3 0.1 3.0 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Lum_binding PF00677.12 ETO26832.1 - 0.073 12.9 1.7 9.6 6.1 0.1 3.4 3 0 0 3 3 3 0 Lumazine binding domain Archease PF01951.11 ETO26833.1 - 1.4e-44 151.3 0.4 1.8e-44 150.9 0.3 1.1 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) TPR_11 PF13414.1 ETO26834.1 - 7.1e-21 73.6 13.6 3.9e-05 23.2 0.8 5.4 4 1 1 5 5 5 5 TPR repeat TPR_12 PF13424.1 ETO26834.1 - 1.1e-13 50.8 11.5 0.018 14.9 0.0 6.1 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 ETO26834.1 - 2.5e-12 45.9 8.6 0.06 13.5 0.1 6.3 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO26834.1 - 7e-11 41.0 15.0 0.02 14.6 0.1 7.8 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO26834.1 - 3.5e-10 39.0 14.3 0.043 13.7 0.8 7.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO26834.1 - 7.3e-10 38.0 22.6 0.0035 16.8 0.7 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO26834.1 - 1.3e-09 37.8 0.0 2.8 8.8 0.0 6.0 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO26834.1 - 3.1e-07 30.6 2.2 0.086 13.1 0.0 5.0 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETO26834.1 - 2e-05 24.3 1.0 0.12 12.2 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 ETO26834.1 - 2.7e-05 23.3 0.3 0.035 13.1 0.1 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO26834.1 - 3.5e-05 24.3 1.5 2.4 8.9 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO26834.1 - 0.00019 20.9 3.4 1.1 9.2 0.2 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO26834.1 - 0.0079 16.5 2.0 74 4.1 0.0 5.3 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 ETO26834.1 - 0.33 10.9 4.6 7.5 6.6 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat PH PF00169.24 ETO26835.1 - 3.5e-08 33.5 0.4 3.5e-08 33.5 0.2 2.0 2 1 0 2 2 2 1 PH domain PH_8 PF15409.1 ETO26835.1 - 0.00015 21.8 0.8 0.00029 20.8 0.5 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 ETO26835.1 - 0.00098 18.9 0.7 0.00098 18.9 0.5 1.6 2 0 0 2 2 2 1 PH domain Myosin_TH1 PF06017.8 ETO26835.1 - 0.016 14.5 1.9 0.021 14.1 0.7 1.6 1 1 0 1 1 1 0 Myosin tail DUF761 PF05553.6 ETO26835.1 - 0.092 12.1 2.2 0.28 10.5 1.5 1.9 1 1 0 1 1 1 0 Cotton fibre expressed protein Menin PF05053.8 ETO26835.1 - 0.092 10.8 2.6 0.11 10.6 1.8 1.1 1 0 0 1 1 1 0 Menin Mononeg_mRNAcap PF14318.1 ETO26835.1 - 0.11 11.5 3.6 0.12 11.3 2.5 1.1 1 0 0 1 1 1 0 Mononegavirales mRNA-capping region V PH_11 PF15413.1 ETO26835.1 - 0.81 9.9 7.1 0.83 9.9 1.0 3.1 2 2 0 2 2 2 0 Pleckstrin homology domain TerY-C PF15616.1 ETO26835.1 - 1.3 8.9 4.1 2.2 8.2 2.2 1.8 2 1 0 2 2 2 0 TerY-C metal binding domain Apis_Csd PF11671.3 ETO26835.1 - 1.5 8.5 11.6 3 7.6 8.0 1.5 1 0 0 1 1 1 0 Complementary sex determiner protein ubiquitin PF00240.18 ETO26836.1 - 2.8e-20 71.4 0.1 1e-19 69.6 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 ETO26836.1 - 7.9e-13 47.9 0.3 1.4e-12 47.0 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 ETO26836.1 - 2.9e-05 24.2 0.1 5.9e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.4 ETO26836.1 - 0.002 18.2 0.1 0.0035 17.5 0.1 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 ETO26836.1 - 0.0021 17.9 0.0 0.0046 16.8 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PIP5K PF01504.13 ETO26836.1 - 0.044 12.8 0.1 0.048 12.7 0.0 1.3 1 1 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Telomere_Sde2 PF13019.1 ETO26836.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Telomere stability and silencing DUF1563 PF07599.6 ETO26836.1 - 3.5 7.5 6.4 0.28 11.1 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1563) DUF3793 PF12672.2 ETO26838.1 - 0.047 13.2 0.2 0.12 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) DUF506 PF04720.7 ETO26839.1 - 0.12 12.0 2.7 0.19 11.3 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF506) DUF1980 PF09323.5 ETO26839.1 - 5.9 6.5 7.0 0.54 9.9 1.1 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1980) Ank PF00023.25 ETO26840.1 - 2.1e-08 33.5 0.6 1.6e-06 27.5 0.0 3.6 3 1 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 ETO26840.1 - 2.4e-08 34.2 0.2 3.4e-06 27.2 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO26840.1 - 8.2e-06 25.5 0.2 0.0091 16.1 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 ETO26840.1 - 7.7e-05 23.0 1.1 0.041 14.4 0.0 4.0 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO26840.1 - 0.0001 22.3 1.0 0.003 17.7 0.0 3.3 5 0 0 5 5 5 1 Ankyrin repeats (many copies) WHEP-TRS PF00458.15 ETO26840.1 - 3.9 7.2 9.2 3.4 7.4 4.7 2.0 2 0 0 2 2 2 0 WHEP-TRS domain NAD_binding_2 PF03446.10 ETO26841.1 - 0.015 15.1 0.3 0.13 12.1 0.1 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase AAA PF00004.24 ETO26842.1 - 8.5e-36 123.0 0.0 1.6e-35 122.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 ETO26842.1 - 6.9e-08 32.5 0.0 1.2e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 ETO26842.1 - 3e-06 27.5 0.0 7.7e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ETO26842.1 - 5e-06 26.6 0.2 0.00078 19.5 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO26842.1 - 2.4e-05 25.1 0.0 7.7e-05 23.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETO26842.1 - 2.6e-05 24.3 0.0 4.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 ETO26842.1 - 4.2e-05 23.2 0.0 0.00029 20.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 ETO26842.1 - 0.00014 21.5 0.0 0.0003 20.4 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 ETO26842.1 - 0.00055 19.1 0.0 0.00088 18.4 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 ETO26842.1 - 0.00071 18.6 0.0 0.0017 17.3 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 ETO26842.1 - 0.0012 19.0 0.1 0.0038 17.5 0.0 1.8 2 0 0 2 2 1 1 ABC transporter RuvB_N PF05496.7 ETO26842.1 - 0.0013 17.8 0.0 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 ETO26842.1 - 0.0024 17.7 0.0 0.0077 16.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain Baculo_11_kDa PF06143.6 ETO26842.1 - 0.0026 17.1 0.2 0.0026 17.1 0.1 2.2 2 1 0 2 2 1 1 Baculovirus 11 kDa family AAA_3 PF07726.6 ETO26842.1 - 0.0026 17.3 0.0 0.0052 16.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 ETO26842.1 - 0.0034 16.1 0.0 0.0054 15.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_11 PF13086.1 ETO26842.1 - 0.018 14.6 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 ETO26842.1 - 0.025 14.7 0.0 0.054 13.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase CoA_binding_3 PF13727.1 ETO26842.1 - 0.031 14.1 1.8 4.4 7.0 0.3 2.5 2 0 0 2 2 2 0 CoA-binding domain ResIII PF04851.10 ETO26842.1 - 0.049 13.4 0.0 0.18 11.6 0.0 1.9 2 1 0 2 2 1 0 Type III restriction enzyme, res subunit AAA_14 PF13173.1 ETO26842.1 - 0.056 13.3 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 ETO26842.1 - 0.065 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NB-ARC PF00931.17 ETO26842.1 - 0.081 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain UPF0079 PF02367.12 ETO26842.1 - 0.081 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DEAD PF00270.24 ETO26842.1 - 0.11 11.9 0.0 13 5.2 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase Zeta_toxin PF06414.7 ETO26842.1 - 0.13 11.3 0.0 0.28 10.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.7 ETO26842.1 - 0.19 11.4 0.1 0.19 11.4 0.0 2.5 3 0 0 3 3 3 0 NACHT domain Herpes_gE PF02480.11 ETO26842.1 - 0.22 9.7 0.0 0.31 9.2 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF788 PF05620.6 ETO26842.1 - 0.37 10.6 3.2 9.4 6.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF788) GED PF02212.13 ETO26843.1 - 0.0046 16.8 0.2 0.13 12.2 0.0 2.6 2 1 0 2 2 2 1 Dynamin GTPase effector domain DpnD-PcfM PF14207.1 ETO26843.1 - 0.064 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 DpnD/PcfM-like protein YL1 PF05764.8 ETO26845.1 - 0.00031 20.4 22.2 0.00039 20.1 15.4 1.2 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.9 ETO26845.1 - 0.00059 17.9 18.5 0.0007 17.7 12.8 1.2 1 0 0 1 1 1 1 CDC45-like protein Pilt PF15453.1 ETO26845.1 - 0.0024 17.6 3.8 0.0027 17.4 2.6 1.1 1 0 0 1 1 1 1 Protein incorporated later into Tight Junctions SDA1 PF05285.7 ETO26845.1 - 0.0031 16.8 25.5 0.0036 16.6 17.7 1.2 1 0 0 1 1 1 1 SDA1 Prothymosin PF03247.9 ETO26845.1 - 0.011 15.8 32.0 0.019 15.1 22.2 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family DUF4618 PF15397.1 ETO26845.1 - 0.018 14.4 6.8 0.024 13.9 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) CENP-T PF15511.1 ETO26845.1 - 0.051 12.8 10.6 0.056 12.6 7.4 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Daxx PF03344.10 ETO26845.1 - 0.085 11.3 22.4 0.099 11.1 15.5 1.1 1 0 0 1 1 1 0 Daxx Family CobT PF06213.7 ETO26845.1 - 0.1 11.6 21.9 0.14 11.2 15.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Herpes_DNAp_acc PF04929.7 ETO26845.1 - 0.12 11.3 4.1 0.17 10.7 2.8 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor RRN3 PF05327.6 ETO26845.1 - 0.17 9.9 14.5 0.21 9.6 10.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF1510 PF07423.6 ETO26845.1 - 0.23 10.8 18.5 0.27 10.5 12.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2890 PF11081.3 ETO26845.1 - 0.83 9.6 12.2 1.1 9.2 8.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Nop14 PF04147.7 ETO26845.1 - 3.3 5.5 38.3 4 5.2 26.5 1.2 1 1 0 1 1 1 0 Nop14-like family RNA_polI_A34 PF08208.6 ETO26845.1 - 3.9 7.1 17.5 5.3 6.6 12.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Drc1-Sld2 PF11719.3 ETO26845.1 - 4.2 6.3 15.8 6.2 5.7 11.0 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein Cwf_Cwc_15 PF04889.7 ETO26845.1 - 5.2 6.7 26.3 2.2 7.9 16.3 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SAPS PF04499.10 ETO26845.1 - 6.8 5.2 9.9 7.4 5.0 6.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop53 PF07767.6 ETO26845.1 - 7 5.5 28.2 14 4.5 19.6 1.5 1 1 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Astro_capsid PF03115.9 ETO26845.1 - 7.1 4.7 8.8 7.5 4.6 6.1 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor TMCO5 PF14992.1 ETO26846.1 - 0.00023 20.4 5.8 0.00031 19.9 4.0 1.2 1 0 0 1 1 1 1 TMCO5 family AAA_27 PF13514.1 ETO26846.1 - 0.026 12.2 6.8 0.03 12.0 4.7 1.0 1 0 0 1 1 1 0 AAA domain Vfa1 PF08432.5 ETO26846.1 - 0.026 14.5 6.5 0.037 14.0 4.5 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Atg14 PF10186.4 ETO26846.1 - 0.029 13.3 7.9 0.035 13.0 5.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Baculo_PEP_C PF04513.7 ETO26846.1 - 0.12 12.2 0.2 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus VIT1 PF01988.14 ETO26846.1 - 0.12 11.8 1.3 0.16 11.4 0.1 1.8 1 1 1 2 2 2 0 VIT family DOR PF14839.1 ETO26846.1 - 0.13 11.9 4.6 0.17 11.6 3.2 1.1 1 0 0 1 1 1 0 DOR family RRF PF01765.14 ETO26846.1 - 0.18 11.2 10.0 0.2 11.0 6.3 1.6 1 1 0 1 1 1 0 Ribosome recycling factor Peptidase_S46 PF10459.4 ETO26846.1 - 0.18 10.1 5.6 0.24 9.7 3.9 1.1 1 0 0 1 1 1 0 Peptidase S46 Occludin_ELL PF07303.8 ETO26846.1 - 0.25 12.0 9.9 1.1 10.0 2.3 2.6 1 1 2 3 3 3 0 Occludin homology domain Mei5 PF10376.4 ETO26846.1 - 0.27 10.7 12.9 0.52 9.8 1.9 2.1 1 1 1 2 2 2 0 Double-strand recombination repair protein APG6 PF04111.7 ETO26846.1 - 0.32 10.0 9.7 0.41 9.6 6.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Peptidase_M41 PF01434.13 ETO26846.1 - 0.69 9.3 6.5 3.2 7.1 3.4 2.0 1 1 1 2 2 2 0 Peptidase family M41 SlyX PF04102.7 ETO26846.1 - 8.2 6.8 11.0 19 5.6 0.1 3.3 1 1 2 3 3 3 0 SlyX FKBP_C PF00254.23 ETO26847.1 - 1.6e-11 44.0 0.0 2.9e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DENN PF02141.16 ETO26848.1 - 7.7e-34 117.0 3.6 1.2e-33 116.3 2.5 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain SPA PF08616.5 ETO26848.1 - 0.06 13.0 0.1 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 Stabilization of polarity axis DUF843 PF05814.6 ETO26849.1 - 0.85 9.4 5.5 1.5 8.7 2.3 2.4 2 1 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) Raftlin PF15250.1 ETO26850.1 - 0.2 10.1 7.0 0.33 9.4 4.8 1.2 1 0 0 1 1 1 0 Raftlin Zn_clus PF00172.13 ETO26850.1 - 1.5 8.8 10.4 1 9.3 5.0 2.3 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 ETO26851.1 - 6.8e-78 254.0 15.3 4.1e-14 51.8 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO26851.1 - 6e-14 52.2 0.0 6.9e-09 35.6 0.0 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO26851.1 - 4.9e-10 38.1 1.5 0.03 12.4 0.0 4.3 1 1 3 4 4 4 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO26851.1 - 1.7e-08 34.2 0.6 0.00012 21.6 0.0 2.1 1 1 1 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 ETO26851.1 - 5.7e-08 31.9 4.3 0.16 10.6 0.4 5.1 1 1 3 4 4 4 3 Nup133 N terminal like PD40 PF07676.7 ETO26851.1 - 5.5e-05 22.7 4.8 6.4 6.5 0.0 4.6 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat BBS2_Mid PF14783.1 ETO26851.1 - 7.9e-05 22.3 0.6 2.5 7.9 0.0 4.8 2 2 3 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Resistin PF06954.6 ETO26851.1 - 8.9e-05 22.6 0.1 22 5.4 0.0 4.5 2 1 0 4 4 4 0 Resistin DUF1258 PF06869.7 ETO26851.1 - 0.0016 17.6 0.3 0.14 11.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1258) DPPIV_N PF00930.16 ETO26851.1 - 0.0025 16.4 0.2 5.1 5.5 0.1 4.0 1 1 3 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Cytochrom_D1 PF02239.11 ETO26851.1 - 0.0093 14.3 0.4 1.5 7.0 0.1 2.7 1 1 2 3 3 3 2 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 ETO26851.1 - 0.012 14.9 4.9 21 4.5 0.0 4.6 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Hira PF07569.6 ETO26851.1 - 0.016 14.4 0.2 9.5 5.3 0.0 3.6 1 1 3 4 4 4 0 TUP1-like enhancer of split MMS1_N PF10433.4 ETO26851.1 - 0.037 12.1 0.1 2.4 6.2 0.0 2.9 1 1 2 3 3 3 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term DEAD PF00270.24 ETO26852.1 - 1.8e-34 118.6 0.0 2.5e-32 111.6 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 ETO26852.1 - 1.2e-27 95.5 0.0 4e-27 93.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain WD40 PF00400.27 ETO26853.1 - 3.9e-33 112.1 0.9 3.1e-12 45.8 0.0 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO26853.1 - 2.6e-05 22.6 0.3 0.0026 16.1 0.0 1.6 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO26853.1 - 0.00076 18.3 1.7 0.41 9.3 0.3 2.4 1 1 1 2 2 2 2 Nup133 N terminal like PD40 PF07676.7 ETO26853.1 - 0.023 14.3 0.5 28 4.5 0.0 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Lactonase PF10282.4 ETO26853.1 - 0.16 11.0 0.0 0.44 9.5 0.0 1.8 1 1 0 1 1 1 0 Lactonase, 7-bladed beta-propeller DBP10CT PF08147.7 ETO26853.1 - 0.56 10.0 0.1 0.56 10.0 0.1 3.1 4 0 0 4 4 4 0 DBP10CT (NUC160) domain Proteasome_A_N PF10584.4 ETO26853.1 - 2.3 7.5 7.3 17 4.8 0.0 4.2 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature G-alpha PF00503.15 ETO26854.1 - 4.9e-12 45.2 2.2 4.9e-12 45.2 1.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit ABC_tran PF00005.22 ETO26854.1 - 0.017 15.3 1.2 0.018 15.3 0.2 1.5 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 ETO26854.1 - 0.019 14.4 0.1 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 ETO26854.1 - 0.02 14.0 0.1 0.022 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arf PF00025.16 ETO26854.1 - 0.066 12.4 0.2 0.1 11.8 0.1 1.4 1 1 0 1 1 1 0 ADP-ribosylation factor family Miro PF08477.8 ETO26854.1 - 0.08 13.4 0.7 0.095 13.2 0.1 1.5 2 0 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 ETO26854.1 - 0.13 12.2 0.4 0.19 11.7 0.1 1.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase zf-DHHC PF01529.15 ETO26855.1 - 1.2e-12 47.6 1.1 2.3e-12 46.6 0.7 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase PLAC8 PF04749.12 ETO26855.1 - 0.031 14.8 0.9 0.052 14.1 0.6 1.4 1 0 0 1 1 1 0 PLAC8 family RskA PF10099.4 ETO26856.1 - 0.11 12.2 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA MA3 PF02847.12 ETO26857.1 - 6.3e-25 87.0 0.3 4.8e-13 48.8 0.1 2.8 2 1 0 2 2 2 2 MA3 domain ACDC PF14733.1 ETO26857.1 - 0.028 14.5 0.1 11 6.2 0.1 2.8 2 1 0 2 2 2 0 AP2-coincident C-terminal DUF240 PF03086.9 ETO26857.1 - 0.046 13.3 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 MG032/MG096/MG288 family 2 FWWh PF14922.1 ETO26858.1 - 0.0055 16.2 1.9 0.042 13.3 0.2 2.1 2 0 0 2 2 2 2 Protein of unknown function Pkinase PF00069.20 ETO26859.1 - 2.1e-21 76.2 0.0 3.3e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO26859.1 - 0.0087 15.1 0.1 0.015 14.3 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase PHTB1_N PF14727.1 ETO26860.1 - 1.9e-46 158.9 0.0 2.3e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 PTHB1 N-terminus UBA_e1_C PF09358.5 ETO26861.1 - 2.5e-36 124.6 0.4 7.8e-36 122.9 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 ETO26861.1 - 3.9e-34 116.0 0.4 7.1e-25 86.3 0.0 2.8 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein ThiF PF00899.16 ETO26861.1 - 4.8e-31 107.3 0.1 1.1e-30 106.2 0.1 1.6 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.4 ETO26861.1 - 5.3e-25 86.5 0.5 2.3e-21 74.9 0.0 2.6 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site DUF427 PF04248.7 ETO26862.1 - 0.15 11.7 0.0 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF427) 2-Hacid_dh_C PF02826.14 ETO26863.1 - 0.11 11.6 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Paf67 PF10255.4 ETO26864.1 - 5.9e-72 242.7 13.7 1.6e-71 241.3 9.5 1.7 1 1 0 1 1 1 1 RNA polymerase I-associated factor PAF67 G-gamma PF00631.17 ETO26864.1 - 0.005 16.5 0.4 0.015 15.0 0.3 1.8 1 0 0 1 1 1 1 GGL domain ABC2_membrane PF01061.19 ETO26865.1 - 2.4e-28 98.7 15.8 3.6e-28 98.1 11.0 1.2 1 0 0 1 1 1 1 ABC-2 type transporter DUF1357 PF07094.6 ETO26865.1 - 0.024 14.0 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1357) ABC2_membrane_3 PF12698.2 ETO26865.1 - 0.7 8.8 15.8 0.31 10.0 9.3 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein PHTB1_C PF14728.1 ETO26866.1 - 3.3e-28 98.5 1.0 4e-28 98.2 0.7 1.1 1 0 0 1 1 1 1 PTHB1 C-terminus WD40 PF00400.27 ETO26868.1 - 1.1e-82 269.2 13.1 3.6e-13 48.8 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat PD40 PF07676.7 ETO26868.1 - 6e-09 35.3 11.7 0.0053 16.4 0.2 6.9 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat Kelch_6 PF13964.1 ETO26868.1 - 2.6e-07 30.5 1.2 0.024 14.8 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Nup160 PF11715.3 ETO26868.1 - 4.2e-06 25.2 2.2 1.3 7.0 0.0 4.6 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Kelch_4 PF13418.1 ETO26868.1 - 0.00021 21.0 0.5 0.06 13.1 0.0 3.4 2 1 1 3 3 3 1 Galactose oxidase, central domain Cytochrom_D1 PF02239.11 ETO26868.1 - 0.01 14.1 0.8 0.33 9.1 0.0 2.8 2 1 0 3 3 3 0 Cytochrome D1 heme domain Kelch_3 PF13415.1 ETO26868.1 - 0.026 14.7 0.0 0.51 10.5 0.0 3.1 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO26868.1 - 0.026 14.4 1.4 2.2 8.3 0.2 3.7 4 0 0 4 4 4 0 Kelch motif Proteasome_A_N PF10584.4 ETO26868.1 - 0.044 13.1 10.3 10 5.5 0.4 5.4 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Kelch_1 PF01344.20 ETO26868.1 - 0.053 13.0 0.3 0.053 13.0 0.2 2.7 3 0 0 3 3 3 0 Kelch motif PLD_C PF12357.3 ETO26868.1 - 0.11 12.0 3.0 13 5.3 0.0 5.0 4 2 2 6 6 6 0 Phospholipase D C terminal Kelch_2 PF07646.10 ETO26868.1 - 0.12 12.2 2.0 8.6 6.3 0.1 3.9 3 0 0 3 3 3 0 Kelch motif Ras PF00071.17 ETO26869.1 - 1.7e-11 43.7 0.2 2.5e-11 43.2 0.2 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO26869.1 - 0.0063 16.9 0.0 0.015 15.7 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein WD40 PF00400.27 ETO26870.1 - 7.6e-59 193.6 23.0 3.2e-11 42.6 0.2 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO26870.1 - 2.7e-18 65.4 7.3 0.0004 18.6 0.1 6.3 1 1 4 6 6 6 6 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO26870.1 - 8.6e-07 29.2 3.3 8.6e-07 29.2 2.3 2.2 2 0 0 2 2 2 1 TRAF-type zinc finger DUF972 PF06156.8 ETO26870.1 - 0.0031 17.8 2.2 0.0031 17.8 1.5 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF972) bZIP_1 PF00170.16 ETO26870.1 - 0.01 15.7 3.5 0.01 15.7 2.4 2.9 3 0 0 3 3 3 0 bZIP transcription factor Atg14 PF10186.4 ETO26870.1 - 0.019 13.9 25.7 0.25 10.2 1.8 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 ETO26870.1 - 0.37 10.3 18.2 0.57 9.7 2.7 3.0 2 0 0 2 2 2 0 Septum formation initiator DUF2968 PF11180.3 ETO26870.1 - 0.38 10.1 13.8 1.5 8.1 2.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) TPR_11 PF13414.1 ETO26871.1 - 3.4e-23 81.0 17.9 9.9e-07 28.3 1.3 4.6 3 1 1 4 4 4 4 TPR repeat TPR_1 PF00515.23 ETO26871.1 - 5.5e-21 73.2 11.2 0.00096 18.6 0.0 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETO26871.1 - 3.3e-20 70.3 16.3 9.1e-05 22.0 0.2 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 ETO26871.1 - 8.2e-17 60.9 33.3 2.2e-08 33.9 2.6 5.4 3 1 3 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 ETO26871.1 - 1.9e-15 55.6 14.3 0.00021 21.2 0.5 7.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 ETO26871.1 - 3.6e-13 48.2 18.2 0.0026 17.4 0.1 6.3 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO26871.1 - 1.3e-12 47.1 0.5 0.07 13.7 0.0 5.4 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO26871.1 - 3.5e-12 46.6 1.6 0.0022 18.5 0.2 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat SAM_1 PF00536.25 ETO26871.1 - 1.9e-09 37.5 0.1 3.7e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) TPR_7 PF13176.1 ETO26871.1 - 8e-09 34.6 14.2 0.036 13.8 0.5 6.2 7 0 0 7 7 6 3 Tetratricopeptide repeat SAM_2 PF07647.12 ETO26871.1 - 2.6e-08 33.5 0.1 6.4e-08 32.3 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) TPR_19 PF14559.1 ETO26871.1 - 3.7e-08 33.5 10.0 0.015 15.6 0.3 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat Sel1 PF08238.7 ETO26871.1 - 0.027 15.1 6.1 2.1 9.0 0.2 4.2 4 0 0 4 4 4 0 Sel1 repeat TPR_6 PF13174.1 ETO26871.1 - 0.084 13.3 5.8 9.3 6.9 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat HHH_5 PF14520.1 ETO26871.1 - 0.12 12.6 0.1 0.53 10.5 0.1 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain TPR_1 PF00515.23 ETO26872.1 - 1.2e-05 24.6 0.3 2.2e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO26872.1 - 0.00067 20.0 0.0 0.0013 19.2 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO26872.1 - 0.00099 18.8 0.1 0.0019 17.9 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO26872.1 - 0.0026 18.0 0.0 0.0055 17.0 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO26872.1 - 0.0086 15.9 0.1 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat Suf PF05843.9 ETO26872.1 - 0.017 14.8 0.0 0.031 13.9 0.0 1.4 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) TPR_11 PF13414.1 ETO26872.1 - 0.11 12.1 0.1 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 TPR repeat Aa_trans PF01490.13 ETO26873.1 - 0.00018 20.1 0.1 0.00027 19.5 0.0 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Pex24p PF06398.6 ETO26873.1 - 0.0019 17.0 0.5 0.0019 17.0 0.3 2.8 2 1 1 3 3 3 1 Integral peroxisomal membrane peroxin IncA PF04156.9 ETO26873.1 - 0.0059 16.2 11.2 0.0059 16.2 7.7 4.7 3 1 1 4 4 4 1 IncA protein Baculo_11_kDa PF06143.6 ETO26873.1 - 0.012 15.0 1.1 0.058 12.7 0.7 2.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family TACC PF05010.9 ETO26873.1 - 0.015 15.0 17.6 0.015 15.0 12.2 3.1 4 0 0 4 4 4 0 Transforming acidic coiled-coil-containing protein (TACC) Sex_peptide PF08138.6 ETO26873.1 - 0.13 12.1 0.4 1.3 8.8 0.1 2.8 2 0 0 2 2 2 0 Sex peptide (SP) family Rpr2 PF04032.11 ETO26873.1 - 0.23 11.3 5.8 0.43 10.4 1.2 3.1 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain PTH2 PF01981.11 ETO26875.1 - 5.6e-11 42.1 0.2 1.9e-10 40.4 0.0 1.9 2 1 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 UBA PF00627.26 ETO26875.1 - 0.0027 17.5 4.0 0.0095 15.7 0.3 2.9 2 1 0 2 2 2 1 UBA/TS-N domain FtsJ PF01728.14 ETO26876.1 - 4.5e-06 26.7 0.1 8.9e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase TMEM51 PF15345.1 ETO26876.1 - 0.12 12.0 3.2 7.7 6.1 1.5 2.2 1 1 1 2 2 2 0 Transmembrane protein 51 FtsJ PF01728.14 ETO26877.1 - 7.5e-35 120.5 0.8 9.6e-35 120.1 0.1 1.5 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 ETO26877.1 - 0.026 15.1 0.1 0.11 13.0 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain TH1 PF04858.8 ETO26877.1 - 0.034 12.3 0.0 0.047 11.8 0.0 1.1 1 0 0 1 1 1 0 TH1 protein Pkinase PF00069.20 ETO26878.1 - 4.4e-36 124.3 0.6 6.4e-36 123.8 0.4 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO26878.1 - 4.4e-08 32.5 0.6 1e-06 28.0 0.1 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 ETO26878.1 - 0.009 15.3 0.2 0.68 9.2 0.0 2.2 2 0 0 2 2 2 2 PhoP regulatory network protein YrbL Beta-lactamase PF00144.19 ETO26879.1 - 1.7e-06 27.2 0.0 2.4e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3403 PF11883.3 ETO26879.1 - 0.13 12.5 0.7 0.63 10.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3403) GTP_EFTU PF00009.22 ETO26880.1 - 2.5e-45 154.2 0.0 5e-45 153.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 ETO26880.1 - 4.8e-09 36.2 0.0 1.7e-08 34.5 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 ETO26880.1 - 4.5e-07 29.8 0.1 5.8e-06 26.3 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 G-alpha PF00503.15 ETO26880.1 - 1.5e-05 23.9 10.5 3.9e-05 22.5 7.0 1.9 2 0 0 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.18 ETO26880.1 - 0.0014 18.5 0.0 0.0051 16.7 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase CDC45 PF02724.9 ETO26880.1 - 9.8 4.0 15.1 16 3.4 10.5 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF2315 PF10231.4 ETO26881.1 - 0.0053 16.6 0.3 0.0057 16.5 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2315) ABC_membrane PF00664.18 ETO26882.1 - 2e-31 109.4 4.0 2.4e-31 109.1 2.8 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region Abi PF02517.11 ETO26882.1 - 0.09 12.9 1.7 0.16 12.0 1.2 1.5 1 1 0 1 1 1 0 CAAX protease self-immunity DUF3464 PF11947.3 ETO26882.1 - 0.13 11.7 0.6 0.26 10.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF4349 PF14257.1 ETO26882.1 - 0.23 10.6 0.7 0.55 9.4 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF2397 PF09660.5 ETO26882.1 - 1 7.8 2.5 1.5 7.3 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) DUF4131 PF13567.1 ETO26882.1 - 1.4 8.2 5.0 5.9 6.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) PolyA_pol PF01743.15 ETO26883.1 - 4.3e-20 72.1 0.0 1.5e-19 70.4 0.0 1.9 2 1 0 2 2 2 1 Poly A polymerase head domain Colicin_im PF03857.8 ETO26883.1 - 0.011 15.5 2.9 0.017 14.8 2.0 1.2 1 0 0 1 1 1 0 Colicin immunity protein VPS9 PF02204.13 ETO26884.1 - 2.1e-11 43.7 0.1 5.8e-10 39.1 0.0 2.7 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Daxx PF03344.10 ETO26884.1 - 0.16 10.4 40.4 0.28 9.6 28.0 1.3 1 0 0 1 1 1 0 Daxx Family HECA PF15353.1 ETO26885.1 - 0.038 13.6 0.2 0.73 9.5 0.0 2.4 2 0 0 2 2 2 0 Headcase protein family homologue RasGEF_N PF00618.15 ETO26886.1 - 0.12 12.4 0.6 0.2 11.7 0.4 1.3 1 0 0 1 1 1 0 RasGEF N-terminal motif BAF1_ABF1 PF04684.8 ETO26886.1 - 3.5 6.3 10.3 4.8 5.9 7.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CorC_HlyC PF03471.12 ETO26887.1 - 6.2e-23 80.3 0.9 2e-21 75.5 0.1 2.3 2 1 1 3 3 3 2 Transporter associated domain CBS PF00571.23 ETO26887.1 - 5.8e-08 32.4 0.0 1.3e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 CBS domain SR-25 PF10500.4 ETO26888.1 - 0.002 17.6 9.0 0.002 17.6 6.2 4.2 5 0 0 5 5 5 2 Nuclear RNA-splicing-associated protein LANC_like PF05147.8 ETO26890.1 - 3e-13 49.0 0.1 3.5e-13 48.8 0.1 1.0 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein Band_7 PF01145.20 ETO26891.1 - 0.0044 16.9 0.7 0.007 16.2 0.5 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Rotavirus_VP1 PF12289.3 ETO26891.1 - 0.037 13.6 0.1 0.074 12.6 0.1 1.5 1 0 0 1 1 1 0 Rotavirus VP1 structural protein Kelch_4 PF13418.1 ETO26892.1 - 7.5e-11 41.6 0.7 1e-08 34.8 0.2 2.4 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO26892.1 - 7.4e-09 35.4 0.8 0.0048 17.0 0.0 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.20 ETO26892.1 - 2.8e-07 29.9 0.2 0.01 15.3 0.0 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 ETO26892.1 - 4.5e-06 26.6 5.4 7.6e-06 25.9 0.2 3.0 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO26892.1 - 0.00045 20.1 0.2 0.0011 18.8 0.1 1.7 1 0 0 1 1 1 1 Kelch motif Kelch_2 PF07646.10 ETO26892.1 - 0.0011 18.7 0.2 0.058 13.1 0.2 2.7 2 1 0 2 2 2 1 Kelch motif WSK PF03832.8 ETO26893.1 - 0.026 13.8 2.7 0.057 12.7 1.9 1.5 1 0 0 1 1 1 0 WSK motif Dysbindin PF04440.11 ETO26894.1 - 0.029 14.1 0.2 0.035 13.8 0.2 1.1 1 0 0 1 1 1 0 Dysbindin (Dystrobrevin binding protein 1) DUF3108 PF11306.3 ETO26894.1 - 0.054 13.1 0.4 0.056 13.0 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3108) PhaP_Bmeg PF09602.5 ETO26894.1 - 0.068 12.9 0.3 0.077 12.8 0.2 1.1 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) La PF05383.12 ETO26895.1 - 1.3e-16 60.1 0.1 3.8e-16 58.6 0.0 1.9 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 ETO26895.1 - 2.7e-06 26.9 0.0 0.024 14.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO26895.1 - 0.00053 19.9 0.0 0.07 13.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DrsE PF02635.10 ETO26896.1 - 0.024 14.6 0.5 0.07 13.1 0.1 1.7 1 1 1 2 2 2 0 DsrE/DsrF-like family Hid1 PF12722.2 ETO26896.1 - 2.1 5.9 6.8 2.4 5.7 4.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DAO PF01266.19 ETO26897.1 - 2.3e-39 135.3 0.0 3.6e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETO26897.1 - 0.0022 16.9 1.6 0.005 15.7 1.1 1.6 1 0 0 1 1 1 1 FAD binding domain G10 PF01125.12 ETO26897.1 - 0.0091 15.5 0.0 0.0091 15.5 0.0 2.0 2 0 0 2 2 2 1 G10 protein Pyr_redox_2 PF07992.9 ETO26897.1 - 0.015 15.1 0.2 0.015 15.1 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 ETO26897.1 - 0.049 13.2 2.6 0.055 13.1 0.1 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 ETO26897.1 - 0.061 12.3 0.6 0.12 11.3 0.5 1.5 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 ETO26897.1 - 0.2 10.7 5.4 0.031 13.3 0.8 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETO26897.1 - 0.3 11.1 1.7 0.8 9.7 1.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 ETO26897.1 - 3.1 6.1 6.7 0.14 10.5 0.6 1.6 2 0 0 2 2 2 0 HI0933-like protein Sulfatase PF00884.18 ETO26898.1 - 1.4e-36 126.2 2.1 1.4e-35 122.9 1.4 2.1 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 ETO26898.1 - 6.3e-05 22.4 4.3 0.00023 20.5 3.0 1.8 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase RGS PF00615.14 ETO26899.1 - 4.5e-09 36.4 0.1 1.2e-08 35.0 0.1 1.7 1 1 0 1 1 1 1 Regulator of G protein signaling domain ICMT PF04140.9 ETO26899.1 - 0.42 10.8 5.5 0.18 12.0 1.5 2.2 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family AIG2 PF06094.7 ETO26900.1 - 1.4e-05 25.4 0.0 2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family AIG2_2 PF13772.1 ETO26900.1 - 0.0068 16.4 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family GATase PF00117.23 ETO26901.1 - 2.4e-15 56.4 0.4 8e-15 54.7 0.0 2.1 1 1 1 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 ETO26901.1 - 2.3e-05 23.9 0.2 2.3e-05 23.9 0.1 2.2 2 1 0 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.19 ETO26901.1 - 0.013 14.9 0.0 0.043 13.2 0.0 2.0 1 0 0 1 1 1 0 DJ-1/PfpI family GATase_3 PF07685.9 ETO26901.1 - 0.1 12.2 0.1 0.1 12.2 0.1 2.1 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain Macoilin PF09726.4 ETO26901.1 - 0.25 9.5 16.4 0.32 9.2 11.4 1.1 1 0 0 1 1 1 0 Transmembrane protein LMBR1 PF04791.11 ETO26901.1 - 1.2 7.6 6.4 1.7 7.1 4.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Pkinase PF00069.20 ETO26902.1 - 3.9e-15 55.7 7.2 7e-15 54.8 5.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO26902.1 - 5.9e-05 22.2 3.4 9.3e-05 21.6 2.4 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_U9 PF03420.8 ETO26902.1 - 0.098 11.9 0.3 0.16 11.1 0.2 1.3 1 0 0 1 1 1 0 Prohead core protein protease DUF3087 PF11286.3 ETO26903.1 - 0.012 14.8 0.1 0.026 13.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) dNK PF01712.14 ETO26904.1 - 1.3e-15 57.5 0.4 3.3e-15 56.2 0.0 1.9 2 1 0 2 2 2 1 Deoxynucleoside kinase AAA_33 PF13671.1 ETO26904.1 - 1.1e-05 25.3 0.0 0.00017 21.4 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 ETO26904.1 - 6.5e-05 23.2 1.0 0.0011 19.2 0.2 2.9 1 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 ETO26904.1 - 0.00013 21.9 0.0 0.027 14.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain Thymidylate_kin PF02223.12 ETO26904.1 - 0.00034 20.0 0.0 0.0011 18.3 0.0 1.9 2 0 0 2 2 2 1 Thymidylate kinase Cullin PF00888.17 ETO26905.1 - 2.3e-53 181.6 8.6 2.8e-53 181.3 6.0 1.0 1 0 0 1 1 1 1 Cullin family SF3a60_bindingd PF12108.3 ETO26905.1 - 0.078 12.5 0.4 0.18 11.3 0.3 1.6 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain Cullin_Nedd8 PF10557.4 ETO26906.1 - 8.4e-25 86.3 4.7 1.4e-24 85.6 3.2 1.4 1 0 0 1 1 1 1 Cullin protein neddylation domain Cullin PF00888.17 ETO26906.1 - 2.4e-11 42.9 5.3 1.6e-10 40.1 0.2 2.0 2 0 0 2 2 2 2 Cullin family Inhibitor_I71 PF12628.2 ETO26906.1 - 0.085 12.5 2.6 0.12 11.9 1.8 1.3 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor Glyco_transf_15 PF01793.11 ETO26906.1 - 1.6 7.6 6.1 1.4 7.7 3.6 1.4 1 1 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DSPc PF00782.15 ETO26907.1 - 9.9e-21 73.7 2.5 1.6e-20 73.0 0.1 2.3 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain MEDS PF14417.1 ETO26907.1 - 0.0018 17.3 0.6 0.71 8.9 0.0 2.3 2 0 0 2 2 2 2 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Y_phosphatase3 PF13350.1 ETO26907.1 - 0.098 12.8 0.2 0.75 10.0 0.0 2.5 2 1 1 3 3 3 0 Tyrosine phosphatase family FmdE PF02663.9 ETO26907.1 - 0.14 12.0 0.7 0.91 9.4 0.0 2.4 1 1 1 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Radial_spoke PF04712.7 ETO26908.1 - 2.4e-05 23.3 0.5 0.015 14.0 0.0 2.1 1 1 1 2 2 2 2 Radial spokehead-like protein SID-1_RNA_chan PF13965.1 ETO26908.1 - 0.74 7.9 3.3 0.28 9.2 0.6 1.4 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 TFIIA_gamma_N PF02268.11 ETO26909.1 - 9e-12 44.3 0.0 1.2e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 ETO26909.1 - 7.7e-10 38.4 0.1 1.2e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit DUF1896 PF08989.5 ETO26909.1 - 0.11 12.4 0.2 0.76 9.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1896) DUF1985 PF09331.6 ETO26911.1 - 0.057 13.2 4.7 4 7.2 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1985) NTP_transf_4 PF13562.1 ETO26913.1 - 0.0066 16.1 3.0 0.028 14.0 0.2 2.9 3 0 0 3 3 3 1 Sugar nucleotidyl transferase Lzipper-MIP1 PF14389.1 ETO26913.1 - 0.04 14.0 0.7 0.04 14.0 0.5 2.5 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 PhoU PF01895.14 ETO26913.1 - 0.2 12.1 3.8 3 8.3 0.1 3.4 3 0 0 3 3 3 0 PhoU domain Kelch_6 PF13964.1 ETO26914.1 - 0.026 14.6 0.2 0.31 11.2 0.0 2.8 4 0 0 4 4 4 0 Kelch motif WD40 PF00400.27 ETO26914.1 - 0.46 10.4 5.1 5.1 7.1 0.0 3.9 4 0 0 4 4 4 0 WD domain, G-beta repeat Mlf1IP PF10248.4 ETO26915.1 - 0.031 13.8 0.1 0.052 13.1 0.1 1.4 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Vma12 PF11712.3 ETO26915.1 - 0.053 13.2 1.9 0.079 12.6 1.2 1.5 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase COX16 PF14138.1 ETO26915.1 - 6.8 6.9 7.0 1.9 8.6 0.5 2.6 3 0 0 3 3 3 0 Cytochrome c oxidase assembly protein COX16 DUF1056 PF06341.6 ETO26916.1 - 0.12 12.4 0.7 0.24 11.4 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1056) Ribosomal_S8 PF00410.14 ETO26917.1 - 7e-18 64.7 0.1 3.5e-16 59.2 0.1 2.2 1 1 0 1 1 1 1 Ribosomal protein S8 IncA PF04156.9 ETO26918.1 - 8.7e-05 22.1 4.6 8.7e-05 22.1 3.2 2.8 3 0 0 3 3 3 1 IncA protein GlutR_dimer PF00745.15 ETO26919.1 - 0.035 14.0 2.5 0.053 13.4 1.8 1.3 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain CENP-F_leu_zip PF10473.4 ETO26919.1 - 0.21 11.4 8.0 1.9 8.3 2.1 2.5 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IF2_N PF04760.10 ETO26919.1 - 0.26 10.9 2.8 0.25 11.0 0.6 1.9 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region RNase_HII PF01351.13 ETO26919.1 - 0.31 10.6 2.4 0.37 10.4 1.7 1.1 1 0 0 1 1 1 0 Ribonuclease HII TMF_DNA_bd PF12329.3 ETO26919.1 - 0.52 10.1 10.6 0.11 12.3 2.3 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Lzipper-MIP1 PF14389.1 ETO26919.1 - 1 9.5 12.5 2 8.5 3.7 2.1 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Snapin_Pallidin PF14712.1 ETO26919.1 - 1.9 8.8 10.5 0.32 11.3 3.6 2.2 1 1 1 2 2 2 0 Snapin/Pallidin SNAPc19 PF15497.1 ETO26919.1 - 3 8.1 9.5 1.4 9.1 0.5 2.4 2 1 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Fzo_mitofusin PF04799.8 ETO26919.1 - 3 7.1 7.4 4 6.7 1.2 2.1 2 0 0 2 2 2 0 fzo-like conserved region DASH_Dad4 PF08650.5 ETO26919.1 - 3.9 7.4 6.2 1.7 8.5 0.6 2.2 1 1 1 2 2 2 0 DASH complex subunit Dad4 GrpE PF01025.14 ETO26919.1 - 4.1 6.9 7.7 1.6 8.2 2.6 1.9 1 1 0 2 2 2 0 GrpE DUF972 PF06156.8 ETO26919.1 - 8 6.8 8.5 4.6 7.6 2.2 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF3010 PF11215.3 ETO26922.1 - 0.014 15.2 0.3 0.018 14.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3010) DDRGK PF09756.4 ETO26922.1 - 0.023 14.1 11.2 0.028 13.8 7.8 1.2 1 0 0 1 1 1 0 DDRGK domain CDC45 PF02724.9 ETO26922.1 - 0.024 12.7 2.3 0.021 12.9 1.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Fmp27 PF10344.4 ETO26922.1 - 0.032 11.9 3.3 0.038 11.6 2.3 1.0 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 CPSF100_C PF13299.1 ETO26922.1 - 0.034 14.3 2.7 0.043 13.9 1.8 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Ycf1 PF05758.7 ETO26922.1 - 0.056 11.1 2.7 0.054 11.2 1.9 1.1 1 0 0 1 1 1 0 Ycf1 Vfa1 PF08432.5 ETO26922.1 - 0.13 12.2 9.2 0.17 11.8 6.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3530 PF12048.3 ETO26922.1 - 0.17 10.8 3.7 0.21 10.5 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Sigma70_ner PF04546.8 ETO26922.1 - 0.22 11.1 8.9 0.31 10.6 6.2 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Pox_Ag35 PF03286.9 ETO26922.1 - 0.44 10.0 8.4 0.69 9.4 5.8 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CCDC66 PF15236.1 ETO26922.1 - 0.49 10.0 17.2 0.61 9.6 11.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 YqfQ PF14181.1 ETO26922.1 - 0.72 9.8 8.7 0.96 9.4 6.0 1.2 1 0 0 1 1 1 0 YqfQ-like protein FAM176 PF14851.1 ETO26922.1 - 0.75 9.4 4.4 1.1 8.9 3.1 1.2 1 0 0 1 1 1 0 FAM176 family RR_TM4-6 PF06459.7 ETO26922.1 - 0.93 9.3 9.2 1.2 9.0 6.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EIIBC-GUT_N PF03612.9 ETO26922.1 - 1.2 8.7 3.6 1.5 8.4 2.5 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Trypan_PARP PF05887.6 ETO26922.1 - 1.3 8.8 5.3 1.8 8.4 3.7 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FAM178 PF14816.1 ETO26922.1 - 1.8 7.1 10.6 2.3 6.8 7.3 1.1 1 0 0 1 1 1 0 Family of unknown function, FAM178 Peptidase_S49_N PF08496.5 ETO26922.1 - 2 8.1 7.4 2.7 7.7 5.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2115 PF09888.4 ETO26922.1 - 2.5 8.1 8.9 0.32 11.0 3.4 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) Atrophin-1 PF03154.10 ETO26922.1 - 3.8 5.5 7.2 4.3 5.3 5.0 1.1 1 0 0 1 1 1 0 Atrophin-1 family DDHD PF02862.12 ETO26922.1 - 3.9 7.2 7.2 5.3 6.7 5.0 1.2 1 0 0 1 1 1 0 DDHD domain DUF1510 PF07423.6 ETO26922.1 - 4.2 6.6 13.5 5.4 6.3 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Sec62 PF03839.11 ETO26922.1 - 5.3 6.3 8.6 6.6 6.0 6.0 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4337 PF14235.1 ETO26922.1 - 6 6.6 7.3 8.1 6.2 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) P-mevalo_kinase PF04275.9 ETO26923.1 - 0.019 14.6 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 Phosphomevalonate kinase CAF1C_H4-bd PF12265.3 ETO26924.1 - 0.00013 21.7 1.9 0.00035 20.3 0.1 2.6 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Menin PF05053.8 ETO26924.1 - 0.011 13.9 9.3 0.014 13.6 6.5 1.1 1 0 0 1 1 1 0 Menin Pex14_N PF04695.8 ETO26924.1 - 0.094 12.7 9.8 0.16 12.0 6.8 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3439 PF11921.3 ETO26924.1 - 0.27 11.0 2.7 0.63 9.7 1.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Macoilin PF09726.4 ETO26924.1 - 0.44 8.7 14.6 0.57 8.4 10.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Neur_chan_memb PF02932.11 ETO26924.1 - 2.5 7.8 8.1 4.4 7.1 5.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1754 PF08555.5 ETO26924.1 - 5 7.7 11.7 9.5 6.8 8.1 1.4 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) ArsA_ATPase PF02374.10 ETO26925.1 - 5.5e-66 222.6 0.1 7e-66 222.3 0.0 1.1 1 0 0 1 1 1 1 Anion-transporting ATPase FlaC_arch PF05377.6 ETO26925.1 - 3.8 7.4 7.4 0.67 9.8 1.2 2.7 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Rootletin PF15035.1 ETO26926.1 - 0.97 9.3 7.9 2.6 8.0 5.4 1.7 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion GAGA_bind PF06217.7 ETO26927.1 - 0.098 12.6 1.9 0.11 12.3 1.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Nop14 PF04147.7 ETO26927.1 - 0.13 10.1 11.8 0.15 9.9 8.2 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 ETO26927.1 - 0.19 10.1 13.2 0.22 9.9 9.1 1.1 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 ETO26927.1 - 0.93 8.8 15.5 1.4 8.2 10.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NOA36 PF06524.7 ETO26927.1 - 5.7 6.0 11.5 6.7 5.8 8.0 1.2 1 0 0 1 1 1 0 NOA36 protein CAP_GLY PF01302.20 ETO26929.1 - 0.0015 18.1 0.0 0.0029 17.2 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain Unstab_antitox PF09720.5 ETO26929.1 - 0.16 11.6 1.2 57 3.5 1.6 3.1 4 0 0 4 4 4 0 Putative addiction module component SID-1_RNA_chan PF13965.1 ETO26929.1 - 0.18 9.9 1.0 0.23 9.5 0.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RHD3 PF05879.7 ETO26930.1 - 6.2e-77 259.1 29.8 3.2e-32 111.3 10.4 5.1 2 1 2 4 4 4 4 Root hair defective 3 GTP-binding protein (RHD3) DUF456 PF04306.8 ETO26930.1 - 0.06 13.3 2.0 0.11 12.4 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) EamA PF00892.15 ETO26931.1 - 1.5e-14 54.1 29.4 2.5e-11 43.7 12.8 2.3 1 1 1 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.10 ETO26931.1 - 0.0039 16.3 1.9 0.0048 16.0 0.0 1.9 2 0 0 2 2 2 1 Nucleotide-sugar transporter TPT PF03151.11 ETO26931.1 - 0.013 15.2 19.3 0.034 13.8 13.4 1.7 1 1 0 1 1 1 0 Triose-phosphate Transporter family DUF3963 PF13124.1 ETO26931.1 - 5.7 6.8 9.7 0.43 10.3 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3963) PHD PF00628.24 ETO26936.1 - 2.2e-09 36.8 9.8 2.2e-09 36.8 6.8 2.1 2 0 0 2 2 2 1 PHD-finger Tetraspannin PF00335.15 ETO26937.1 - 7.6 5.7 16.8 0.15 11.3 4.0 2.1 1 1 0 2 2 2 0 Tetraspanin family DUF310 PF03750.8 ETO26938.1 - 0.095 12.8 5.9 0.39 10.9 1.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF310) Med15 PF09606.5 ETO26941.1 - 7.3e-05 21.1 25.7 8.8e-05 20.9 17.8 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal zinc_ribbon_5 PF13719.1 ETO26941.1 - 0.018 14.5 1.2 2.6 7.6 0.0 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 ETO26941.1 - 0.019 14.6 1.5 2.4 7.8 0.1 2.8 2 0 0 2 2 2 0 zinc-ribbon domain DUF4175 PF13779.1 ETO26941.1 - 0.089 10.4 31.2 0.16 9.6 21.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SprA-related PF12118.3 ETO26941.1 - 0.09 12.0 25.1 0.012 14.9 14.4 1.7 2 0 0 2 2 2 0 SprA-related family TMEM51 PF15345.1 ETO26941.1 - 0.31 10.6 13.9 0.044 13.4 6.7 1.8 2 0 0 2 2 2 0 Transmembrane protein 51 RR_TM4-6 PF06459.7 ETO26941.1 - 0.6 9.9 12.2 0.92 9.3 8.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3408 PF11888.3 ETO26941.1 - 2.2 8.2 14.1 3.6 7.5 8.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) PAT1 PF09770.4 ETO26941.1 - 2.4 6.2 29.9 0.014 13.7 14.4 1.7 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Folate_carrier PF01770.13 ETO26941.1 - 2.8 6.3 6.2 4.2 5.7 4.3 1.2 1 0 0 1 1 1 0 Reduced folate carrier zf-C2H2_4 PF13894.1 ETO26941.1 - 3.1 8.3 11.4 5.6 7.5 0.4 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger Peptidase_S15 PF02129.13 ETO26941.1 - 4 6.7 10.3 8.5 5.7 7.1 1.5 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Bud13 PF09736.4 ETO26941.1 - 5.1 7.3 23.6 0.42 10.8 12.6 1.9 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex AUX_IAA PF02309.11 ETO26941.1 - 6.5 6.4 14.3 1.4 8.6 7.3 1.8 2 0 0 2 2 2 0 AUX/IAA family DUF788 PF05620.6 ETO26941.1 - 7.5 6.3 9.8 15 5.4 6.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF788) AIF_C PF14721.1 ETO26941.1 - 9.9 6.4 10.6 28 4.9 7.3 1.7 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Nop14 PF04147.7 ETO26943.1 - 0.00026 19.0 8.5 0.00032 18.7 5.9 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.7 ETO26943.1 - 0.001 18.4 10.1 0.0014 17.9 7.0 1.2 1 0 0 1 1 1 1 SDA1 DUF1510 PF07423.6 ETO26943.1 - 0.0072 15.7 10.5 0.0072 15.7 7.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) CDC45 PF02724.9 ETO26943.1 - 0.033 12.2 7.6 0.05 11.6 5.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Trypan_PARP PF05887.6 ETO26943.1 - 0.22 11.3 9.9 0.35 10.6 6.9 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Sporozoite_P67 PF05642.6 ETO26943.1 - 1.3 6.7 10.2 1.8 6.2 7.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2457 PF10446.4 ETO26943.1 - 1.7 7.3 17.7 3.2 6.3 12.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ada_Zn_binding PF02805.11 ETO26947.1 - 0.02 14.5 1.3 0.037 13.6 0.9 1.4 1 0 0 1 1 1 0 Metal binding domain of Ada DUF2722 PF10846.3 ETO26948.1 - 0.00072 18.7 2.2 0.00085 18.4 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF2031 PF09592.5 ETO26949.1 - 0.08 12.0 2.3 0.14 11.2 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) DUF2681 PF10883.3 ETO26950.1 - 0.68 10.1 0.0 0.68 10.1 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2681) Herpes_UL95 PF03038.9 ETO26950.1 - 7.3 5.3 8.0 4.1 6.2 0.5 2.3 1 1 1 2 2 2 0 UL95 family Pkinase PF00069.20 ETO26951.1 - 1.2e-55 188.5 0.0 1.9e-55 187.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO26951.1 - 4.4e-25 88.2 0.0 6.1e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO26951.1 - 1.7e-07 30.5 0.1 1.6e-05 24.0 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Brix PF04427.13 ETO26951.1 - 0.0065 16.1 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Brix domain Seadorna_VP7 PF07387.6 ETO26951.1 - 0.03 13.1 0.0 0.049 12.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 cNMP_binding PF00027.24 ETO26953.1 - 1e-06 28.4 0.0 1.6e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain dUTPase PF00692.14 ETO26954.1 - 1.4e-35 121.5 0.0 4.9e-24 84.2 0.0 2.1 2 0 0 2 2 2 2 dUTPase zf-RING_2 PF13639.1 ETO26955.1 - 1.6e-10 40.6 9.3 1.6e-10 40.6 6.5 3.5 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 ETO26955.1 - 4.9e-07 29.3 9.0 4.9e-07 29.3 6.2 3.2 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETO26955.1 - 1.1e-05 25.3 5.7 1.1e-05 25.3 4.0 3.4 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 ETO26955.1 - 2.3e-05 23.9 7.3 2.3e-05 23.9 5.0 3.4 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO26955.1 - 2.3e-05 24.3 9.4 2.3e-05 24.3 6.5 3.8 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO26955.1 - 0.0054 16.4 9.1 0.0054 16.4 6.3 3.0 2 1 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 ETO26955.1 - 0.0078 16.0 1.7 0.0078 16.0 1.2 3.2 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H_2 PF13832.1 ETO26955.1 - 0.011 15.7 1.5 0.011 15.7 1.0 3.9 3 1 1 4 4 4 0 PHD-zinc-finger like domain DUF2184 PF09950.4 ETO26955.1 - 0.022 13.7 0.3 0.11 11.4 0.0 2.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2184) PHD PF00628.24 ETO26955.1 - 0.44 10.2 30.0 1.3 8.8 4.5 4.3 2 1 1 3 3 3 0 PHD-finger Adaptin_binding PF10199.4 ETO26955.1 - 1.3 9.2 14.1 0.8 9.9 3.1 3.0 3 0 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 zf-RING_2 PF13639.1 ETO26957.1 - 1.7e-10 40.5 9.3 1.7e-10 40.5 6.5 3.4 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 ETO26957.1 - 5.1e-07 29.2 9.0 5.1e-07 29.2 6.2 3.0 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETO26957.1 - 1.3e-06 28.4 16.2 1.7e-06 28.0 2.1 2.8 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 ETO26957.1 - 2.4e-05 23.8 7.3 2.4e-05 23.8 5.0 3.0 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO26957.1 - 2.4e-05 24.2 9.4 2.4e-05 24.2 6.5 3.8 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.1 ETO26957.1 - 0.0031 17.4 15.7 0.0031 17.4 0.5 3.8 2 1 1 3 3 3 1 PHD-zinc-finger like domain zf-RING_5 PF14634.1 ETO26957.1 - 0.0056 16.3 9.1 0.0056 16.3 6.3 2.9 2 1 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 ETO26957.1 - 0.0093 15.7 1.9 0.0093 15.7 1.3 3.1 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2184 PF09950.4 ETO26957.1 - 0.031 13.3 0.2 0.12 11.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2184) PHD PF00628.24 ETO26957.1 - 0.59 9.8 30.0 1.2 8.8 4.5 4.1 2 1 1 3 3 3 0 PHD-finger zf-HC5HC2H PF13771.1 ETO26957.1 - 1.1 9.4 17.6 0.028 14.5 2.4 3.1 2 1 0 2 2 2 0 PHD-like zinc-binding domain Tom22 PF04281.8 ETO26957.1 - 6 6.4 8.1 0.82 9.1 0.3 2.3 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 RNA_pol_Rpb2_4 PF04566.8 ETO26958.1 - 0.081 12.7 1.8 0.26 11.1 1.2 1.9 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 4 DUF773 PF05600.7 ETO26959.1 - 0.018 13.8 9.4 0.029 13.1 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF773) Med14 PF08638.6 ETO26960.1 - 0.052 12.7 0.2 0.11 11.6 0.1 1.4 1 1 0 1 1 1 0 Mediator complex subunit MED14 7TM_GPCR_Srv PF10323.4 ETO26962.1 - 0.088 11.9 0.2 0.089 11.8 0.2 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv Lipase_GDSL_3 PF14606.1 ETO26962.1 - 0.46 10.1 5.1 0.63 9.7 3.1 1.5 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Apc1 PF12859.2 ETO26963.1 - 1e-08 35.2 1.0 4.2e-08 33.3 0.0 2.5 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 1 Reticulon PF02453.12 ETO26964.1 - 0.00092 18.8 0.9 0.00092 18.8 0.6 1.6 2 0 0 2 2 2 1 Reticulon Pex24p PF06398.6 ETO26964.1 - 0.0069 15.2 2.0 0.0069 15.2 1.4 1.6 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin Mer2 PF09074.5 ETO26964.1 - 0.018 15.0 4.6 0.018 15.0 3.2 2.2 2 0 0 2 2 2 0 Mer2 Striatin PF08232.7 ETO26964.1 - 0.062 13.6 1.0 0.062 13.6 0.7 3.0 2 1 1 3 3 3 0 Striatin family Borrelia_orfA PF02414.10 ETO26964.1 - 0.17 10.9 12.3 0.086 11.9 2.5 2.1 2 0 0 2 2 2 0 Borrelia ORF-A ING PF12998.2 ETO26964.1 - 2.7 8.3 14.0 0.1 12.8 5.0 1.9 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF4446 PF14584.1 ETO26964.1 - 6.2 6.6 7.1 0.28 11.0 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF3450 PF11932.3 ETO26965.1 - 7.6e-05 22.0 13.7 7.6e-05 22.0 9.5 2.6 1 1 2 3 3 3 1 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.7 ETO26965.1 - 0.0048 16.6 14.6 0.0048 16.6 10.1 3.0 2 1 1 3 3 3 1 TPR/MLP1/MLP2-like protein Fez1 PF06818.10 ETO26965.1 - 0.0055 16.7 29.5 0.0055 16.7 20.4 1.5 2 0 0 2 2 2 1 Fez1 Spc7 PF08317.6 ETO26965.1 - 0.17 10.4 31.8 0.015 13.9 17.0 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF948 PF06103.6 ETO26965.1 - 0.21 11.4 5.6 0.55 10.1 2.9 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TMP_2 PF06791.8 ETO26965.1 - 2.8 7.5 6.3 0.53 9.8 1.5 1.9 2 1 0 2 2 2 0 Prophage tail length tape measure protein DUF2937 PF11157.3 ETO26965.1 - 9.8 5.4 7.3 2.3 7.5 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) Aminotran_5 PF00266.14 ETO26966.1 - 2.1e-06 26.7 0.0 2.5e-06 26.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V vATP-synt_AC39 PF01992.11 ETO26967.1 - 2.5e-06 26.8 0.1 3.6e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit G-alpha PF00503.15 ETO26968.1 - 3e-44 151.2 9.0 1.5e-42 145.6 6.3 2.5 1 1 0 1 1 1 1 G-protein alpha subunit AAA_29 PF13555.1 ETO26968.1 - 0.00048 19.5 0.1 0.0023 17.4 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain NB-ARC PF00931.17 ETO26968.1 - 0.0011 17.9 0.0 0.0025 16.6 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 ETO26968.1 - 0.0033 17.4 0.0 0.0081 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 ETO26968.1 - 0.006 16.4 1.8 0.01 15.7 0.1 2.3 2 1 0 3 3 3 1 AAA domain ABC_tran PF00005.22 ETO26968.1 - 0.014 15.6 0.4 0.014 15.6 0.3 2.3 2 2 0 2 2 2 0 ABC transporter DAP3 PF10236.4 ETO26968.1 - 0.015 14.2 0.1 0.038 12.9 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.7 ETO26968.1 - 0.017 14.7 0.1 0.068 12.8 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_21 PF13304.1 ETO26968.1 - 0.02 14.8 0.9 0.051 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 ETO26968.1 - 0.021 14.5 1.5 0.18 11.4 0.1 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_5 PF07728.9 ETO26968.1 - 0.023 14.4 0.4 0.22 11.2 0.2 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 ETO26968.1 - 0.024 14.0 0.0 0.1 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 ETO26968.1 - 0.032 13.6 0.5 0.075 12.4 0.1 1.8 2 0 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.18 ETO26968.1 - 0.034 14.0 0.0 8.1 6.4 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase Arf PF00025.16 ETO26968.1 - 0.043 13.0 0.8 1.2 8.3 0.0 2.7 2 1 0 2 2 2 0 ADP-ribosylation factor family T2SE PF00437.15 ETO26968.1 - 0.047 12.5 0.0 0.1 11.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 ETO26968.1 - 0.05 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.4 ETO26968.1 - 0.051 12.1 0.1 0.11 11.1 0.1 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF258 PF03193.11 ETO26968.1 - 0.051 12.7 0.9 0.14 11.3 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function, DUF258 DUF815 PF05673.8 ETO26968.1 - 0.062 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 ETO26968.1 - 0.082 12.0 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DUF1829 PF08862.5 ETO26968.1 - 1.2 9.4 5.5 0.25 11.6 0.3 2.5 2 2 2 4 4 3 0 Domain of unknown function DUF1829 AAA_23 PF13476.1 ETO26968.1 - 9.7 6.4 13.5 3.1e+02 1.5 9.3 2.7 1 1 0 1 1 1 0 AAA domain DUF4407 PF14362.1 ETO26971.1 - 3 6.7 7.0 3.2 6.6 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_U57 PF05582.7 ETO26971.1 - 5.2 5.9 7.4 8.2 5.3 5.1 1.3 1 0 0 1 1 1 0 YabG peptidase U57 AAA_23 PF13476.1 ETO26971.1 - 9.9 6.4 16.3 14 5.9 11.3 1.2 1 0 0 1 1 1 0 AAA domain PRTP PF01366.13 ETO26972.1 - 2.4 6.0 7.6 2.8 5.8 5.2 1.2 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Myosin_tail_1 PF01576.14 ETO26973.1 - 0.0005 17.9 31.4 0.0005 17.9 21.7 1.8 1 1 1 2 2 2 2 Myosin tail APG6 PF04111.7 ETO26973.1 - 0.053 12.5 48.0 0.1 11.6 21.3 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF3584 PF12128.3 ETO26973.1 - 0.17 9.2 43.2 0.27 8.5 29.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) EzrA PF06160.7 ETO26973.1 - 1 7.4 37.5 1.3 7.1 26.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA IFT57 PF10498.4 ETO26973.1 - 1.1 7.8 38.9 0.22 10.2 11.3 2.6 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 CHASE3 PF05227.8 ETO26973.1 - 1.6 8.4 24.7 1.3 8.6 0.8 2.3 2 1 0 2 2 2 0 CHASE3 domain Reo_sigmaC PF04582.7 ETO26973.1 - 1.7 7.7 9.4 1.2 8.2 4.5 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Flagellin_C PF00700.16 ETO26973.1 - 1.8 8.7 19.3 1.1 9.4 0.9 3.4 1 1 2 3 3 3 0 Bacterial flagellin C-terminal helical region Tropomyosin PF00261.15 ETO26973.1 - 3 6.8 43.3 0.23 10.5 26.1 1.7 1 1 1 2 2 2 0 Tropomyosin Laminin_II PF06009.7 ETO26973.1 - 3.3 7.4 24.5 11 5.7 9.8 2.5 1 1 1 2 2 2 0 Laminin Domain II Nup54 PF13874.1 ETO26973.1 - 6 6.5 32.7 0.37 10.4 12.7 2.4 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 DUF1664 PF07889.7 ETO26973.1 - 6.4 6.5 22.1 0.12 12.1 6.3 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 ETO26973.1 - 9.6 4.7 41.5 1.1 7.8 5.9 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein WD40 PF00400.27 ETO26974.1 - 1.5e-62 205.4 17.9 2.2e-10 39.9 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO26974.1 - 5.9e-13 47.8 8.5 0.00093 17.4 0.2 5.4 1 1 3 5 5 5 5 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO26974.1 - 0.0015 18.4 0.8 0.14 12.1 0.1 3.7 3 1 1 4 4 4 1 Domain of unknown function (DUF3601) ParA PF10609.4 ETO26975.1 - 1.2e-19 69.9 0.0 2e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 ETO26975.1 - 1.8e-14 53.5 0.0 2.6e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 ETO26975.1 - 2.6e-08 33.2 0.0 5.1e-08 32.3 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 ETO26975.1 - 6.6e-06 25.3 0.4 3.8e-05 22.8 0.0 2.1 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_31 PF13614.1 ETO26975.1 - 7.3e-05 22.7 0.0 0.0005 20.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 ETO26975.1 - 0.0011 17.8 0.0 0.0016 17.2 0.0 1.2 1 0 0 1 1 1 1 ArgK protein DUF258 PF03193.11 ETO26975.1 - 0.007 15.5 0.1 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 ETO26975.1 - 0.016 14.5 0.5 0.023 14.1 0.3 1.4 1 1 0 1 1 1 0 AAA domain YhjQ PF06564.7 ETO26975.1 - 0.021 14.1 0.0 0.042 13.2 0.0 1.5 1 0 0 1 1 1 0 YhjQ protein AAA_17 PF13207.1 ETO26975.1 - 0.027 15.2 0.2 0.046 14.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.15 ETO26975.1 - 0.049 13.2 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.17 ETO26975.1 - 0.056 12.3 0.1 0.085 11.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.7 ETO26975.1 - 0.14 11.2 0.0 2 7.4 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.18 ETO26975.1 - 0.16 11.9 0.4 1.3 8.9 0.3 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase P12 PF12669.2 ETO26975.1 - 0.16 12.1 2.1 0.32 11.2 1.5 1.4 1 0 0 1 1 1 0 Virus attachment protein p12 family AAA_10 PF12846.2 ETO26975.1 - 0.17 11.2 0.1 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain DUF3508 PF12018.3 ETO26976.1 - 1.6e-14 53.5 5.7 1.6e-14 53.5 3.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3508) IL28A PF15177.1 ETO26976.1 - 0.0086 15.6 1.7 0.78 9.2 0.6 2.4 2 0 0 2 2 2 2 Interleukin-28A NYD-SP28 PF14772.1 ETO26976.1 - 0.17 11.9 4.8 0.33 11.0 0.1 2.8 2 0 0 2 2 2 0 Sperm tail Mur_ligase_M PF08245.7 ETO26977.1 - 8.5e-09 35.7 0.1 4e-08 33.5 0.0 1.8 1 1 0 1 1 1 1 Mur ligase middle domain MutS_I PF01624.15 ETO26977.1 - 0.041 13.9 0.1 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 MutS domain I EF-hand_1 PF00036.27 ETO26978.1 - 5e-08 31.6 0.7 1.8e-06 26.8 0.1 2.6 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 ETO26978.1 - 1.3e-07 30.9 1.4 3.8e-06 26.3 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 ETO26978.1 - 1.4e-07 31.5 3.1 3.4e-07 30.2 2.2 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 ETO26978.1 - 2.7e-06 26.4 1.0 7.2e-06 25.1 0.3 2.0 2 0 0 2 2 2 1 EF hand Na_Ca_ex PF01699.19 ETO26978.1 - 1.7e-05 24.4 2.4 1.7e-05 24.4 1.6 1.6 2 0 0 2 2 2 1 Sodium/calcium exchanger protein EF-hand_8 PF13833.1 ETO26978.1 - 9.3e-05 21.9 0.8 0.00067 19.2 0.1 2.5 2 1 0 2 2 2 1 EF-hand domain pair Caleosin PF05042.8 ETO26978.1 - 0.05 13.1 0.0 0.096 12.2 0.0 1.5 1 0 0 1 1 1 0 Caleosin related protein Afi1 PF07792.7 ETO26978.1 - 0.11 12.4 2.7 0.21 11.6 1.9 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Vfa1 PF08432.5 ETO26978.1 - 9.9 6.1 11.8 8.4 6.3 7.0 1.7 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Baculo_LEF5_C PF11792.3 ETO26979.1 - 0.015 14.6 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain ATG13 PF10033.4 ETO26980.1 - 5e-06 26.1 0.0 0.0068 15.8 0.0 2.8 2 0 0 2 2 2 2 Autophagy-related protein 13 UBX PF00789.15 ETO26981.1 - 2e-11 43.8 0.0 4.3e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 UBX domain PGA2 PF07543.7 ETO26981.1 - 0.41 10.4 13.0 0.029 14.1 2.1 2.9 3 0 0 3 3 3 0 Protein trafficking PGA2 NMO PF03060.10 ETO26982.1 - 1.7e-23 83.2 0.0 2.1e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase NMO PF03060.10 ETO26983.1 - 1.1e-24 87.1 0.1 1.5e-24 86.7 0.1 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 ETO26983.1 - 6.7e-05 21.9 0.0 8.7e-05 21.5 0.0 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain AlaDh_PNT_C PF01262.16 ETO26985.1 - 1.3e-25 89.9 0.0 2.1e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 ETO26985.1 - 7.1e-25 87.5 0.0 1.1e-24 87.0 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Saccharop_dh_N PF04455.7 ETO26986.1 - 1.3e-10 41.3 0.1 1.7e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 LOR/SDH bifunctional enzyme conserved region Saccharop_dh PF03435.13 ETO26987.1 - 2.7e-50 171.4 0.0 2.6e-49 168.2 0.0 2.0 1 1 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 ETO26987.1 - 0.049 13.6 0.1 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding PI3Ka PF00613.15 ETO26988.1 - 1.2e-05 24.5 0.4 2.1e-05 23.7 0.3 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) CENP-T PF15511.1 ETO26988.1 - 0.46 9.6 16.6 0.71 9.0 11.5 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Tup_N PF08581.5 ETO26990.1 - 0.02 15.0 5.6 0.033 14.3 3.9 1.3 1 0 0 1 1 1 0 Tup N-terminal DUF4515 PF14988.1 ETO26990.1 - 0.053 13.1 12.3 0.066 12.8 8.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) Svf1 PF08622.5 ETO26990.1 - 0.086 11.8 0.5 0.1 11.5 0.4 1.1 1 0 0 1 1 1 0 Svf1-like Pox_F17 PF04767.7 ETO26990.1 - 0.33 11.2 3.3 0.44 10.8 2.3 1.1 1 0 0 1 1 1 0 DNA-binding 11 kDa phosphoprotein HAUS6_N PF14661.1 ETO26990.1 - 0.4 10.0 7.2 0.49 9.6 5.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus WD40 PF00400.27 ETO26991.1 - 3.3e-05 23.6 0.1 3.3e-05 23.6 0.1 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat IncA PF04156.9 ETO26992.1 - 0.00044 19.9 8.9 0.00044 19.9 6.2 1.8 2 0 0 2 2 2 1 IncA protein CBM_X PF06204.6 ETO26992.1 - 0.034 13.6 0.0 0.27 10.7 0.0 2.6 1 0 0 1 1 1 0 Putative carbohydrate binding domain Neur_chan_memb PF02932.11 ETO26992.1 - 0.069 13.0 3.1 0.16 11.8 2.1 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Shisa PF13908.1 ETO26992.1 - 0.22 11.7 1.3 0.47 10.6 0.0 2.3 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator Herpes_glycop PF01528.11 ETO26992.1 - 0.53 8.9 1.8 0.91 8.1 1.3 1.4 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Peptidase_S49_N PF08496.5 ETO26992.1 - 0.71 9.6 7.1 1.9 8.2 5.0 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Atrophin-1 PF03154.10 ETO26992.1 - 4.2 5.3 21.6 6.9 4.6 15.0 1.3 1 0 0 1 1 1 0 Atrophin-1 family Maf PF02545.9 ETO26993.1 - 0.12 11.4 0.3 0.16 11.0 0.2 1.2 1 0 0 1 1 1 0 Maf-like protein WD40 PF00400.27 ETO26994.1 - 1.7e-65 214.7 10.4 1.7e-13 49.8 0.1 7.2 6 1 1 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO26994.1 - 1.2e-13 51.2 0.8 6.5e-06 25.9 0.0 3.6 2 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO26994.1 - 7.2e-13 47.5 5.2 0.00038 18.7 0.1 4.1 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO26994.1 - 6.2e-06 24.7 3.0 0.01 14.1 0.0 3.1 2 1 1 3 3 3 3 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO26994.1 - 1.4e-05 24.0 4.7 0.3 9.8 0.0 3.8 1 1 1 3 3 3 3 Nup133 N terminal like DPPIV_N PF00930.16 ETO26994.1 - 4.8e-05 22.1 0.1 0.078 11.5 0.0 3.3 2 2 1 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF1513 PF07433.6 ETO26994.1 - 0.00016 20.6 0.1 0.083 11.7 0.1 3.2 1 1 0 3 3 3 2 Protein of unknown function (DUF1513) Coatomer_WDAD PF04053.9 ETO26994.1 - 0.0025 16.6 3.3 0.26 10.0 0.1 3.3 1 1 2 4 4 4 1 Coatomer WD associated region AcetylCoA_hyd_C PF13336.1 ETO26994.1 - 0.033 13.8 0.0 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 Acetyl-CoA hydrolase/transferase C-terminal domain PD40 PF07676.7 ETO26994.1 - 0.034 13.8 3.5 21 4.9 0.0 4.8 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 ETO26994.1 - 0.089 11.8 2.9 9.6 5.1 0.0 4.3 3 2 2 5 5 5 0 Protein of unknown function (DUF1258) Rhomboid PF01694.17 ETO26995.1 - 6.9e-06 26.1 0.0 0.0013 18.7 0.0 2.2 2 0 0 2 2 2 2 Rhomboid family Luteo_coat PF00894.13 ETO26996.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Luteovirus coat protein Fun_ATP-synt_8 PF05933.8 ETO26997.1 - 0.11 12.5 1.7 0.2 11.7 1.2 1.3 1 0 0 1 1 1 0 Fungal ATP synthase protein 8 (A6L) SSP160 PF06933.6 ETO26997.1 - 2.6 5.9 19.8 0.024 12.6 5.9 2.1 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Mucin PF01456.12 ETO26997.1 - 5 6.8 24.0 12 5.6 16.6 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein CH PF00307.26 ETO26998.1 - 4.7e-12 45.8 0.0 6.1e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain Atg14 PF10186.4 ETO26999.1 - 0.043 12.7 9.6 0.058 12.3 6.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Tropomyosin_1 PF12718.2 ETO26999.1 - 0.051 13.4 13.6 0.079 12.8 9.5 1.3 1 0 0 1 1 1 0 Tropomyosin like LPP PF04728.8 ETO26999.1 - 0.059 13.1 0.6 0.13 12.1 0.4 1.5 1 0 0 1 1 1 0 Lipoprotein leucine-zipper FBPase_2 PF06874.6 ETO26999.1 - 0.13 10.2 11.6 0.79 7.6 8.0 1.8 1 1 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase DUF641 PF04859.7 ETO26999.1 - 0.14 11.8 5.1 0.15 11.8 3.0 1.5 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Swi5 PF07061.6 ETO26999.1 - 0.23 11.2 10.1 0.52 10.1 7.0 1.6 1 1 0 1 1 1 0 Swi5 DUF848 PF05852.6 ETO26999.1 - 0.43 10.4 8.0 0.6 9.9 5.6 1.2 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF3573 PF12097.3 ETO26999.1 - 0.46 9.0 8.0 0.62 8.6 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Med4 PF10018.4 ETO26999.1 - 0.68 9.3 10.6 0.89 8.9 7.3 1.1 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Phage_GP20 PF06810.6 ETO26999.1 - 0.85 9.0 15.8 1.3 8.3 11.0 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 TcdA_TcdB PF12919.2 ETO26999.1 - 1 7.7 9.7 1.3 7.3 6.7 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain TMF_DNA_bd PF12329.3 ETO26999.1 - 1.8 8.4 18.6 0.34 10.7 9.8 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding RNA_pol_Rpb1_5 PF04998.12 ETO26999.1 - 6.7 5.8 6.2 8.8 5.4 4.3 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 RNB PF00773.14 ETO27000.1 - 0.027 13.7 0.6 0.034 13.4 0.4 1.1 1 0 0 1 1 1 0 RNB domain zf-MIZ PF02891.15 ETO27000.1 - 0.75 9.3 5.3 0.22 11.0 1.1 2.2 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger PTS_2-RNA PF01885.11 ETO27001.1 - 1.9e-44 151.1 0.3 2e-43 147.8 0.2 2.1 1 1 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family SDA1 PF05285.7 ETO27001.1 - 0.042 13.1 24.5 0.067 12.4 17.0 1.2 1 0 0 1 1 1 0 SDA1 Hid1 PF12722.2 ETO27001.1 - 0.16 9.5 9.1 0.17 9.5 6.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Daxx PF03344.10 ETO27001.1 - 0.23 9.8 19.7 0.27 9.6 13.7 1.1 1 0 0 1 1 1 0 Daxx Family DDHD PF02862.12 ETO27001.1 - 0.33 10.7 11.8 0.54 10.0 8.2 1.3 1 0 0 1 1 1 0 DDHD domain Tfb4 PF03850.9 ETO27001.1 - 0.47 9.6 2.4 0.71 9.0 1.6 1.3 1 0 0 1 1 1 0 Transcription factor Tfb4 CDC45 PF02724.9 ETO27001.1 - 1.6 6.6 20.9 2.3 6.1 14.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 ETO27001.1 - 2 5.9 13.5 2.4 5.7 9.4 1.1 1 0 0 1 1 1 0 Ycf1 Neur_chan_memb PF02932.11 ETO27001.1 - 3.6 7.4 7.5 4.9 6.9 5.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RRN3 PF05327.6 ETO27001.1 - 7.7 4.4 9.4 12 3.8 6.5 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CENP-T PF15511.1 ETO27001.1 - 9.2 5.3 17.0 13 4.9 11.8 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T RP-C_C PF11800.3 ETO27001.1 - 9.5 5.8 10.8 17 5.0 7.5 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region adh_short PF00106.20 ETO27002.1 - 3e-08 33.7 0.0 5.1e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETO27002.1 - 3.1e-05 23.7 0.0 4.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 ETO27002.1 - 4.1e-05 22.7 0.0 0.042 12.9 0.0 2.1 1 1 1 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 ETO27002.1 - 0.00049 20.2 0.1 0.00066 19.7 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 ETO27002.1 - 0.001 18.0 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ApbA PF02558.11 ETO27002.1 - 0.0046 16.4 0.0 0.0057 16.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 ETO27002.1 - 0.0088 16.0 0.0 0.016 15.1 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 ETO27002.1 - 0.0091 15.0 0.0 0.014 14.3 0.0 1.3 1 1 0 1 1 1 1 Saccharopine dehydrogenase Methyltransf_18 PF12847.2 ETO27002.1 - 0.013 16.0 0.0 0.019 15.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain F420_oxidored PF03807.12 ETO27002.1 - 0.031 14.6 0.2 0.053 13.9 0.1 1.5 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.12 ETO27002.1 - 0.052 12.4 0.1 0.076 11.8 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain His_biosynth PF00977.16 ETO27002.1 - 0.053 12.7 0.1 0.062 12.5 0.1 1.2 1 0 0 1 1 1 0 Histidine biosynthesis protein Epimerase PF01370.16 ETO27002.1 - 0.067 12.6 0.0 0.18 11.2 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Nuc_deoxyrib_tr PF05014.10 ETO27002.1 - 0.088 12.6 0.1 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase Eno-Rase_NADH_b PF12242.3 ETO27002.1 - 0.089 12.5 0.1 0.16 11.7 0.0 1.5 1 1 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase IncA PF04156.9 ETO27003.1 - 0.00027 20.5 95.0 0.0007 19.2 0.6 5.2 2 1 3 5 5 5 3 IncA protein bZIP_1 PF00170.16 ETO27003.1 - 0.0024 17.8 1.3 0.0024 17.8 0.9 11.1 5 4 8 13 13 13 2 bZIP transcription factor DivIC PF04977.10 ETO27003.1 - 0.01 15.3 3.0 0.01 15.3 2.1 10.5 4 3 5 10 10 10 0 Septum formation initiator DUF4131 PF13567.1 ETO27003.1 - 0.19 11.1 0.0 0.59 9.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Ribosomal_L22e PF01776.12 ETO27004.1 - 7.8e-15 54.8 0.2 1.5e-14 53.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal L22e protein family ORC6 PF05460.8 ETO27004.1 - 0.14 11.1 9.0 0.16 11.0 6.2 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Mitofilin PF09731.4 ETO27004.1 - 3.3 6.2 11.2 3.3 6.2 7.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Ndc1_Nup PF09531.5 ETO27004.1 - 5 5.4 5.5 4.6 5.5 3.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TPR_12 PF13424.1 ETO27005.1 - 2.2e-29 101.2 0.2 4e-13 49.1 0.0 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO27005.1 - 1.9e-16 59.4 1.9 1e-08 34.6 0.1 3.3 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.1 ETO27005.1 - 2.3e-11 42.6 14.1 0.0019 17.8 0.2 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO27005.1 - 2.4e-11 42.7 14.4 0.0022 17.5 0.1 5.5 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO27005.1 - 4.7e-11 41.6 0.0 0.023 14.4 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO27005.1 - 8.1e-08 31.9 0.0 0.016 15.0 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO27005.1 - 3.3e-07 29.7 5.6 0.41 10.6 0.1 4.9 4 1 0 4 4 4 3 Tetratricopeptide repeat MIT PF04212.13 ETO27005.1 - 0.0028 17.4 1.2 0.84 9.5 0.0 2.9 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 ETO27005.1 - 0.0046 17.3 0.3 6.4 7.4 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat BRCA-2_OB3 PF09104.5 ETO27005.1 - 0.015 15.0 0.4 0.033 13.9 0.3 1.5 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 Pkinase PF00069.20 ETO27007.1 - 2.6e-65 220.1 0.0 4.4e-65 219.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO27007.1 - 1.2e-30 106.5 0.0 1.7e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO27007.1 - 9.3e-06 24.7 0.0 1.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETO27007.1 - 0.0007 18.7 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO27007.1 - 0.0045 16.7 0.0 0.025 14.3 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIB43A PF05914.7 ETO27007.1 - 0.018 13.6 1.6 0.027 13.1 1.1 1.2 1 0 0 1 1 1 0 RIB43A Ubiq_cyt_C_chap PF03981.7 ETO27007.1 - 0.11 12.2 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone DUF3987 PF13148.1 ETO27007.1 - 0.24 9.9 2.3 0.41 9.1 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) RNase_Zc3h12a PF11977.3 ETO27008.1 - 1e-17 64.3 0.0 1.3e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain zf-RanBP PF00641.13 ETO27008.1 - 0.03 13.4 1.9 0.049 12.7 1.3 1.3 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Cytochrom_c3_2 PF14537.1 ETO27008.1 - 0.041 14.2 0.1 0.072 13.4 0.1 1.4 1 0 0 1 1 1 0 Cytochrome c3 CbiX PF01903.12 ETO27008.1 - 0.069 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 CbiX DZR PF12773.2 ETO27008.1 - 0.12 12.2 2.3 0.16 11.8 0.9 1.7 2 0 0 2 2 2 0 Double zinc ribbon EST1_DNA_bind PF10373.4 ETO27009.1 - 1.5e-10 40.7 0.7 9e-10 38.2 0.5 2.1 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain zf-C2H2_4 PF13894.1 ETO27010.1 - 2.3e-05 24.3 12.9 0.0029 17.8 2.5 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 ETO27010.1 - 3.8e-05 23.7 21.4 0.00033 20.8 2.6 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETO27010.1 - 0.0092 16.2 0.2 0.0092 16.2 0.1 4.0 4 0 0 4 4 4 2 Zinc-finger double domain IBR PF01485.16 ETO27010.1 - 0.14 12.0 4.0 0.36 10.7 2.8 1.7 1 0 0 1 1 1 0 IBR domain Fil_haemagg_2 PF13332.1 ETO27010.1 - 1.5 8.6 27.5 2.3 7.9 13.7 2.3 1 1 1 2 2 2 0 Haemagluttinin repeat CLPTM1 PF05602.7 ETO27010.1 - 3.3 6.3 10.8 4.3 5.9 7.5 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) CTP_transf_1 PF01148.15 ETO27011.1 - 0.063 12.9 0.1 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 Cytidylyltransferase family EOS1 PF12326.3 ETO27011.1 - 0.3 10.7 2.9 0.24 11.0 0.2 2.1 1 1 1 2 2 2 0 N-glycosylation protein NYD-SP28 PF14772.1 ETO27012.1 - 7.7e-09 35.5 13.0 7.7e-09 35.5 9.0 6.0 1 1 6 7 7 7 2 Sperm tail NYD-SP28_assoc PF14775.1 ETO27013.1 - 1e-12 47.5 8.4 2.6e-12 46.2 5.8 1.8 1 0 0 1 1 1 1 Sperm tail C-terminal domain Ovate PF04844.8 ETO27013.1 - 0.067 13.0 0.7 2.1 8.2 0.0 2.5 2 0 0 2 2 2 0 Transcriptional repressor, ovate DUF3153 PF11353.3 ETO27013.1 - 0.21 11.0 11.0 0.47 9.8 1.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3153) Filo_glycop PF01611.11 ETO27013.1 - 5.2 5.7 10.9 0.16 10.7 1.9 2.0 2 0 0 2 2 2 0 Filovirus glycoprotein KIAA1430 PF13879.1 ETO27013.1 - 7.4 7.0 12.6 2.3 8.6 6.3 2.0 2 0 0 2 2 2 0 KIAA1430 homologue DUF4512 PF14975.1 ETO27014.1 - 5 8.0 9.5 7.3 7.4 0.6 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4512) TPR_12 PF13424.1 ETO27015.1 - 5.7e-86 282.5 37.6 1.4e-19 69.7 3.3 4.9 2 1 4 6 6 6 6 Tetratricopeptide repeat TPR_11 PF13414.1 ETO27015.1 - 1.1e-43 146.7 64.4 1.1e-11 44.1 1.7 4.5 1 1 5 6 6 6 6 TPR repeat TPR_10 PF13374.1 ETO27015.1 - 2.4e-38 128.9 0.0 1.6e-06 27.8 0.0 7.3 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETO27015.1 - 1.5e-35 119.3 45.8 7.6e-08 31.6 0.4 7.2 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_7 PF13176.1 ETO27015.1 - 5.1e-34 113.3 14.8 6.3e-05 22.4 0.1 7.7 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_8 PF13181.1 ETO27015.1 - 1.5e-31 105.7 42.4 5.3e-06 25.8 0.6 8.2 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.12 ETO27015.1 - 7.4e-27 91.0 30.3 8.1e-05 22.2 0.3 7.5 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 ETO27015.1 - 6.4e-13 47.8 16.7 0.31 11.3 0.6 7.9 7 2 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO27015.1 - 8.7e-13 47.6 0.1 1.6 9.5 0.0 6.9 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO27015.1 - 1.6e-09 38.1 3.8 0.049 14.3 0.3 5.3 2 1 3 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO27015.1 - 6.5e-09 35.6 17.6 0.16 12.4 0.5 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO27015.1 - 1.3e-08 34.8 26.3 0.00011 22.2 7.9 4.4 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.1 ETO27015.1 - 2.7e-08 33.3 15.8 0.00057 19.1 4.2 3.0 1 1 2 3 3 3 2 Soluble NSF attachment protein, SNAP Sel1 PF08238.7 ETO27015.1 - 0.0095 16.5 7.4 11 6.7 0.1 4.9 4 0 0 4 4 4 0 Sel1 repeat RPN7 PF10602.4 ETO27015.1 - 0.016 14.5 16.0 2.8 7.2 0.2 5.3 4 2 2 6 6 6 0 26S proteasome subunit RPN7 TPR_19 PF14559.1 ETO27015.1 - 0.16 12.3 14.5 0.3 11.4 0.8 4.4 4 2 1 5 5 4 0 Tetratricopeptide repeat MIT PF04212.13 ETO27015.1 - 0.35 10.7 19.1 2.3 8.1 1.3 5.6 4 2 2 6 6 5 0 MIT (microtubule interacting and transport) domain MMR_HSR1 PF01926.18 ETO27016.1 - 2.5e-06 27.4 0.0 6.2e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 ETO27016.1 - 5.1e-06 25.4 2.4 0.0001 21.1 1.5 2.6 2 2 0 2 2 2 1 G-protein alpha subunit Gtr1_RagA PF04670.7 ETO27016.1 - 0.00048 19.3 0.2 0.0015 17.6 0.1 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 ETO27016.1 - 0.00053 19.4 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 ETO27016.1 - 0.00089 18.4 0.4 0.039 13.0 0.3 2.6 1 1 0 1 1 1 1 AIG1 family AAA_29 PF13555.1 ETO27016.1 - 0.0024 17.3 0.1 0.0051 16.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 ETO27016.1 - 0.0034 16.5 0.3 0.022 13.9 0.2 2.3 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Mg_chelatase PF01078.16 ETO27016.1 - 0.0073 15.4 0.0 0.027 13.6 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.4 ETO27016.1 - 0.0086 15.5 0.5 0.037 13.5 0.1 2.2 1 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 ETO27016.1 - 0.011 15.4 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 ETO27016.1 - 0.018 15.3 3.1 0.13 12.5 2.1 2.6 1 1 0 1 1 1 0 ABC transporter SRP54 PF00448.17 ETO27016.1 - 0.018 14.5 0.0 0.54 9.6 0.0 2.9 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.1 ETO27016.1 - 0.026 14.1 1.2 0.15 11.5 0.0 2.9 4 0 0 4 4 3 0 AAA domain AAA_17 PF13207.1 ETO27016.1 - 0.029 15.1 0.1 0.17 12.6 0.0 2.3 1 1 0 2 2 2 0 AAA domain T2SE PF00437.15 ETO27016.1 - 0.031 13.1 0.2 0.073 11.9 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 ETO27016.1 - 0.071 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 ETO27016.1 - 0.097 12.9 1.3 0.33 11.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 ETO27016.1 - 0.099 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.18 ETO27016.1 - 0.68 9.7 5.8 0.66 9.7 1.6 2.6 2 1 0 2 2 2 0 Dynamin family AAA_21 PF13304.1 ETO27016.1 - 0.72 9.7 8.8 0.27 11.1 2.7 2.4 1 1 2 3 3 3 0 AAA domain HSP70 PF00012.15 ETO27017.1 - 1e-29 102.9 2.0 1e-29 102.9 1.4 1.4 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 ETO27017.1 - 3.1e-07 29.3 0.1 5.1e-07 28.5 0.0 1.3 1 1 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.3 ETO27017.1 - 0.0037 16.2 0.1 0.013 14.4 0.0 1.8 2 0 0 2 2 2 1 Type IV pilus assembly protein PilM; BatA PF07584.6 ETO27018.1 - 0.019 15.1 2.3 0.019 15.1 1.6 3.5 3 1 0 3 3 3 0 Aerotolerance regulator N-terminal DUF912 PF06024.7 ETO27018.1 - 0.036 14.1 2.1 2.6 8.1 0.2 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) O-ag_pol_Wzy PF14296.1 ETO27018.1 - 0.14 10.7 7.4 0.55 8.7 5.1 1.8 1 1 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy 7TM_GPCR_Srab PF10292.4 ETO27018.1 - 0.68 8.5 5.7 0.051 12.2 0.4 1.7 2 0 0 2 2 2 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor Peptidase_S49_N PF08496.5 ETO27018.1 - 9.1 6.0 9.1 6.2 6.5 5.0 1.8 1 1 0 1 1 1 0 Peptidase family S49 N-terminal Rtf2 PF04641.7 ETO27019.1 - 1.1 8.4 24.4 0.71 9.0 5.1 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger Ldh_1_C PF02866.13 ETO27020.1 - 6.9e-28 97.5 0.8 4.9e-27 94.7 0.0 2.3 2 1 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 ETO27020.1 - 2.2e-16 59.9 0.2 9.4e-16 57.9 0.2 1.9 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain HEAT PF02985.17 ETO27021.1 - 9.9e-08 31.4 0.0 0.0052 16.7 0.0 4.1 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 ETO27021.1 - 2.6e-06 27.6 0.1 0.0037 17.5 0.0 2.4 1 1 1 2 2 2 2 HEAT repeats Adaptin_N PF01602.15 ETO27021.1 - 0.00017 20.0 0.0 0.00023 19.6 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_EZ PF13513.1 ETO27021.1 - 0.021 15.3 0.0 0.068 13.6 0.0 2.0 1 1 0 1 1 1 0 HEAT-like repeat Adaptin_N PF01602.15 ETO27025.1 - 3.5e-105 352.3 11.5 4.4e-105 352.0 8.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 ETO27025.1 - 9.6e-24 84.1 2.8 7.9e-23 81.2 0.0 2.8 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 ETO27025.1 - 5e-13 49.1 4.1 4.5e-06 26.8 0.0 4.8 2 2 2 4 4 4 4 HEAT repeats B2-adapt-app_C PF09066.5 ETO27025.1 - 2e-12 46.9 0.2 5.2e-12 45.6 0.1 1.7 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT PF02985.17 ETO27025.1 - 4.9e-08 32.4 4.2 0.067 13.3 0.0 5.5 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 ETO27025.1 - 0.0017 18.8 1.6 3.3 8.3 0.0 4.8 4 1 1 5 5 5 1 HEAT-like repeat Arm PF00514.18 ETO27025.1 - 0.012 15.4 0.9 0.5 10.2 0.0 3.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat ELK PF03789.8 ETO27025.1 - 0.45 10.3 3.8 1.2 9.0 2.6 1.8 1 0 0 1 1 1 0 ELK domain DUF1510 PF07423.6 ETO27025.1 - 0.95 8.7 19.0 2 7.7 13.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 ETO27025.1 - 5.5 4.9 20.6 8.5 4.2 14.3 1.2 1 0 0 1 1 1 0 CDC45-like protein KOW PF00467.24 ETO27026.1 - 0.0031 17.1 2.5 0.17 11.6 0.1 2.5 2 0 0 2 2 2 2 KOW motif QueF_N PF14819.1 ETO27026.1 - 0.11 12.5 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term ArfGap PF01412.13 ETO27028.1 - 6.1e-29 100.1 0.9 1.5e-28 98.8 0.7 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf C2 PF00168.25 ETO27028.1 - 1.9e-16 59.6 0.1 1.3e-15 56.9 0.0 2.4 3 0 0 3 3 3 1 C2 domain B9-C2 PF07162.6 ETO27028.1 - 0.04 13.7 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Ciliary basal body-associated, B9 protein zf-B_box PF00643.19 ETO27029.1 - 1.2e-06 28.2 9.6 1.2e-06 28.2 6.7 3.4 4 0 0 4 4 4 1 B-box zinc finger zf-C2HC_2 PF13913.1 ETO27029.1 - 8.4e-06 25.3 6.1 8.4e-06 25.3 4.2 3.9 4 0 0 4 4 4 1 zinc-finger of a C2HC-type Sgf11 PF08209.6 ETO27029.1 - 0.0075 15.5 1.5 0.0075 15.5 1.0 3.6 3 1 1 4 4 4 2 Sgf11 (transcriptional regulation protein) HTH_17 PF12728.2 ETO27029.1 - 2.8 8.2 5.4 4.4 7.6 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Atg14 PF10186.4 ETO27030.1 - 1.2e-08 34.2 2.6 9.3e-08 31.3 0.0 2.1 2 0 0 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 Phage_T7_Capsid PF05396.6 ETO27030.1 - 0.0062 16.6 0.3 0.01 16.0 0.2 1.2 1 0 0 1 1 1 1 Phage T7 capsid assembly protein DUF3753 PF12575.3 ETO27031.1 - 0.0019 17.9 2.7 0.0019 17.9 1.9 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3753) DUF2615 PF11027.3 ETO27031.1 - 0.01 15.7 2.1 0.017 15.0 0.6 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2615) DUF2207 PF09972.4 ETO27031.1 - 0.013 14.0 0.2 0.018 13.6 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF912 PF06024.7 ETO27031.1 - 0.019 15.0 2.8 0.019 15.0 1.9 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) RXT2_N PF08595.6 ETO27031.1 - 0.021 14.6 2.0 0.033 13.9 1.4 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Plant_vir_prot PF01307.12 ETO27031.1 - 0.031 13.9 1.7 0.23 11.1 0.1 2.2 2 0 0 2 2 2 0 Plant viral movement protein Intg_mem_TP0381 PF09529.5 ETO27031.1 - 0.06 12.5 1.2 4.7 6.3 0.1 2.1 2 0 0 2 2 2 0 Integral membrane protein (intg_mem_TP0381) DUF1183 PF06682.7 ETO27031.1 - 0.11 12.1 0.7 0.88 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) ATG27 PF09451.5 ETO27031.1 - 0.14 11.4 2.2 0.14 11.3 1.0 1.4 1 1 0 1 1 1 0 Autophagy-related protein 27 ASFV_J13L PF05568.6 ETO27031.1 - 0.14 11.6 0.1 0.14 11.6 0.1 1.8 2 0 0 2 2 2 0 African swine fever virus J13L protein Peptidase_M56 PF05569.6 ETO27031.1 - 0.31 9.9 7.0 0.99 8.3 0.5 2.1 1 1 1 2 2 2 0 BlaR1 peptidase M56 DUF2500 PF10694.4 ETO27031.1 - 1.1 9.2 4.5 11 6.0 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) ODV-E18 PF10717.4 ETO27031.1 - 1.2 8.6 10.5 0.03 13.7 2.3 2.1 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Baculo_11_kDa PF06143.6 ETO27031.1 - 1.4 8.3 12.1 2 7.8 2.1 2.3 2 0 0 2 2 2 0 Baculovirus 11 kDa family ETRAMP PF09716.5 ETO27031.1 - 1.7 8.6 5.2 1.8 8.5 2.1 2.2 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF3169 PF11368.3 ETO27031.1 - 2.1 7.4 9.1 0.38 9.9 1.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) DUF3139 PF11337.3 ETO27031.1 - 2.7 8.3 7.2 17 5.7 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) DUF4448 PF14610.1 ETO27031.1 - 4 6.8 6.3 0.51 9.7 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4448) Ribosomal_L7Ae PF01248.21 ETO27032.1 - 7.1e-26 89.5 0.1 8.9e-26 89.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 ETO27032.1 - 4.4e-05 23.3 0.0 4.4e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 Adenosine_kin PF04008.9 ETO27032.1 - 0.048 13.1 0.0 0.058 12.8 0.0 1.1 1 0 0 1 1 1 0 Adenosine specific kinase AIG1 PF04548.11 ETO27033.1 - 0.13 11.4 0.9 0.15 11.1 0.2 1.5 2 0 0 2 2 2 0 AIG1 family DUF4160 PF13711.1 ETO27034.1 - 0.0005 19.8 0.7 1.5 8.7 0.0 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4160) Phage_Gp23 PF10669.4 ETO27034.1 - 0.08 13.0 0.1 0.08 13.0 0.1 2.1 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) WD40 PF00400.27 ETO27035.1 - 9.4e-25 85.5 6.8 2.1e-05 24.2 0.0 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat SR-25 PF10500.4 ETO27035.1 - 0.097 12.1 8.9 0.18 11.2 6.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ank_2 PF12796.2 ETO27036.1 - 0.0024 18.1 0.6 0.0064 16.8 0.4 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO27036.1 - 0.0072 16.8 0.1 0.026 15.0 0.0 2.1 2 1 0 2 2 2 1 Ankyrin repeats (many copies) VIT1 PF01988.14 ETO27036.1 - 0.023 14.1 0.8 0.032 13.7 0.6 1.2 1 0 0 1 1 1 0 VIT family Ank_5 PF13857.1 ETO27036.1 - 0.05 13.8 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) RSV_NS2 PF03113.9 ETO27036.1 - 0.083 12.8 1.4 0.15 12.0 1.0 1.5 1 0 0 1 1 1 0 Respiratory synctial virus non-structural protein NS2 RasGEF_N PF00618.15 ETO27036.1 - 0.15 12.1 1.2 0.42 10.7 0.0 2.1 1 1 1 2 2 2 0 RasGEF N-terminal motif DUF1829 PF08862.5 ETO27036.1 - 1 9.7 4.5 3 8.1 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function DUF1829 YolD PF08863.5 ETO27036.1 - 8.8 6.2 8.8 20 5.1 1.0 2.9 1 1 2 3 3 3 0 YolD-like protein HSP70 PF00012.15 ETO27037.1 - 0.00091 17.2 0.0 0.0011 16.9 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein DUF912 PF06024.7 ETO27037.1 - 0.12 12.4 7.0 4.3 7.4 3.1 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3357 PF11837.3 ETO27037.1 - 0.21 11.4 2.2 0.94 9.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Secretin_N_2 PF07655.8 ETO27037.1 - 0.6 10.5 10.7 0.83 10.0 7.4 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain DUF1980 PF09323.5 ETO27037.1 - 2.3 7.9 4.6 5 6.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) WD40 PF00400.27 ETO27039.1 - 1.9e-57 189.2 19.4 2.2e-12 46.3 0.1 7.5 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO27039.1 - 9.9e-07 27.2 11.1 0.026 12.6 0.1 5.5 2 2 4 6 6 6 2 Nucleoporin Nup120/160 BBS2_N PF14781.1 ETO27039.1 - 0.015 14.9 0.1 0.095 12.3 0.0 2.4 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal SPX PF03105.14 ETO27039.1 - 0.018 14.8 5.7 0.023 14.5 3.9 1.1 1 0 0 1 1 1 0 SPX domain DUF4200 PF13863.1 ETO27039.1 - 0.067 13.1 12.0 0.057 13.3 7.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF2408 PF10303.4 ETO27039.1 - 0.09 12.8 7.7 0.15 12.1 5.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF1541 PF07563.6 ETO27039.1 - 0.13 11.9 0.8 9.5 5.9 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1541) SUKH_5 PF14567.1 ETO27039.1 - 0.67 9.4 6.5 1.9 7.9 0.0 3.8 4 0 0 4 4 4 0 SMI1-KNR4 cell-wall FlxA PF14282.1 ETO27039.1 - 0.88 9.5 14.1 1.5 8.8 9.8 1.4 1 0 0 1 1 1 0 FlxA-like protein IncA PF04156.9 ETO27039.1 - 1.1 8.8 6.2 1.6 8.3 4.3 1.3 1 0 0 1 1 1 0 IncA protein TPD52 PF04201.10 ETO27039.1 - 7.5 6.2 10.5 25 4.5 7.3 1.8 1 1 0 1 1 1 0 Tumour protein D52 family RP-C_C PF11800.3 ETO27039.1 - 9.8 5.8 6.7 15 5.2 4.6 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Alpha-amylase PF00128.19 ETO27040.1 - 4.9e-47 160.8 0.1 1.8e-23 83.4 0.0 3.0 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Trefoil PF00088.13 ETO27040.1 - 3.4e-11 42.5 12.8 5.9e-11 41.8 8.1 2.0 2 0 0 2 2 2 1 Trefoil (P-type) domain DUF1966 PF09260.6 ETO27040.1 - 0.00037 20.5 0.0 0.00079 19.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Trypan_PARP PF05887.6 ETO27041.1 - 0.00038 20.2 0.5 0.00074 19.3 0.4 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Neisseria_TspB PF05616.8 ETO27041.1 - 0.012 13.9 18.2 0.019 13.3 12.6 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Macoilin PF09726.4 ETO27041.1 - 5 5.2 8.5 5.7 5.0 5.9 1.2 1 0 0 1 1 1 0 Transmembrane protein CAP_GLY PF01302.20 ETO27042.1 - 0.0023 17.5 0.1 0.0044 16.6 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF494 PF04361.8 ETO27042.1 - 0.034 13.8 1.0 0.073 12.7 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF494) DASH_Dam1 PF08653.5 ETO27043.1 - 0.066 12.9 0.2 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 DASH complex subunit Dam1 MTHFR PF02219.12 ETO27043.1 - 0.11 11.6 0.0 0.2 10.7 0.0 1.5 1 1 0 1 1 1 0 Methylenetetrahydrofolate reductase C2 PF00168.25 ETO27044.1 - 2.5e-08 33.6 0.4 1.1e-05 25.2 0.0 3.8 3 0 0 3 3 3 2 C2 domain PH PF00169.24 ETO27045.1 - 8.8e-13 48.3 0.1 2.2e-12 47.0 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 ETO27045.1 - 0.00011 22.3 0.4 0.00051 20.2 0.3 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 ETO27045.1 - 0.00046 20.2 0.5 0.78 9.8 0.0 2.9 1 1 1 2 2 2 2 Pleckstrin homology domain Ras PF00071.17 ETO27045.1 - 0.0089 15.4 0.1 0.028 13.7 0.0 1.9 2 0 0 2 2 2 1 Ras family eIF2A PF08662.6 ETO27046.1 - 7.3e-17 61.7 3.0 1e-06 28.5 0.1 4.9 3 1 0 4 4 4 3 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 ETO27046.1 - 0.48 10.4 5.3 92 3.1 0.0 5.1 6 0 0 6 6 6 0 WD domain, G-beta repeat TRAP_alpha PF03896.11 ETO27047.1 - 0.002 17.1 4.6 0.0025 16.8 3.2 1.2 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF2457 PF10446.4 ETO27047.1 - 0.032 12.9 16.9 0.038 12.7 11.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SID-1_RNA_chan PF13965.1 ETO27047.1 - 0.049 11.8 2.3 0.061 11.4 1.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PGA2 PF07543.7 ETO27047.1 - 0.058 13.1 19.7 0.018 14.8 11.6 1.6 1 1 1 2 2 2 0 Protein trafficking PGA2 Ycf1 PF05758.7 ETO27047.1 - 0.083 10.5 9.0 0.085 10.5 6.3 1.1 1 0 0 1 1 1 0 Ycf1 BSP_II PF05432.6 ETO27047.1 - 0.12 11.6 15.5 0.15 11.3 10.7 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CDC45 PF02724.9 ETO27047.1 - 0.13 10.2 16.8 0.15 10.0 11.6 1.1 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.5 ETO27047.1 - 0.38 11.0 13.4 0.79 9.9 9.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Daxx PF03344.10 ETO27047.1 - 0.48 8.8 21.1 0.54 8.6 14.6 1.1 1 0 0 1 1 1 0 Daxx Family Sigma70_ner PF04546.8 ETO27047.1 - 0.97 9.0 19.9 1.4 8.5 13.5 1.5 1 1 0 1 1 1 0 Sigma-70, non-essential region Presenilin PF01080.12 ETO27047.1 - 1.1 7.9 3.5 1.3 7.8 2.4 1.1 1 0 0 1 1 1 0 Presenilin Tim54 PF11711.3 ETO27047.1 - 1.3 7.5 9.4 1.7 7.1 6.5 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 EBV-NA3 PF05009.7 ETO27047.1 - 1.8 7.7 4.7 2.5 7.2 3.3 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) AF1Q PF15017.1 ETO27047.1 - 1.9 8.4 14.9 5.3 7.0 7.0 2.4 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator Nucleoplasmin PF03066.10 ETO27047.1 - 2.3 7.7 18.2 4 6.9 12.6 1.4 1 0 0 1 1 1 0 Nucleoplasmin Pox_Ag35 PF03286.9 ETO27047.1 - 2.9 7.3 24.2 2.9 7.3 15.6 1.5 1 1 1 2 2 2 0 Pox virus Ag35 surface protein Peptidase_S64 PF08192.6 ETO27047.1 - 3.4 5.8 10.9 4.3 5.5 7.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 Sporozoite_P67 PF05642.6 ETO27047.1 - 5.6 4.7 9.2 5.6 4.6 6.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Gag_spuma PF03276.9 ETO27047.1 - 5.8 5.1 7.8 7 4.8 5.4 1.1 1 0 0 1 1 1 0 Spumavirus gag protein KIAA1430 PF13879.1 ETO27049.1 - 0.0014 19.0 13.4 0.0014 19.0 9.3 2.7 2 1 0 2 2 2 1 KIAA1430 homologue VHP PF02209.14 ETO27049.1 - 0.35 10.5 0.1 0.35 10.5 0.1 2.0 2 0 0 2 2 2 0 Villin headpiece domain Ras PF00071.17 ETO27050.1 - 1.9e-07 30.6 0.1 2.6e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 Ras family Arf PF00025.16 ETO27050.1 - 0.052 12.7 0.0 0.057 12.6 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family Miro PF08477.8 ETO27050.1 - 0.068 13.6 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Miro-like protein Seryl_tRNA_N PF02403.17 ETO27052.1 - 2.2e-12 46.9 15.5 2.5e-11 43.5 1.2 2.4 2 1 0 2 2 2 2 Seryl-tRNA synthetase N-terminal domain DUF3585 PF12130.3 ETO27052.1 - 0.0069 16.2 3.2 0.049 13.4 1.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3585) Phage_holin_1 PF04531.8 ETO27052.1 - 0.04 13.9 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage holin DUF948 PF06103.6 ETO27052.1 - 0.081 12.7 2.6 1.6 8.5 0.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CENP-F_leu_zip PF10473.4 ETO27052.1 - 0.18 11.6 14.5 0.18 11.6 4.5 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YPEB PF14620.1 ETO27052.1 - 0.33 9.9 4.2 0.28 10.1 1.7 1.6 1 1 1 2 2 2 0 YpeB sporulation DUF4446 PF14584.1 ETO27052.1 - 0.8 9.5 6.7 7.5 6.3 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) AAA_23 PF13476.1 ETO27052.1 - 0.86 9.8 11.9 1.2 9.3 8.2 1.3 1 0 0 1 1 1 0 AAA domain Abhydrolase_1 PF00561.15 ETO27054.1 - 0.026 14.0 0.2 0.08 12.4 0.0 1.6 1 1 1 2 2 2 0 alpha/beta hydrolase fold Citrate_ly_lig PF08218.6 ETO27054.1 - 0.042 13.3 0.0 0.054 12.9 0.0 1.1 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain DUF4530 PF15039.1 ETO27055.1 - 5.5 6.9 9.5 15 5.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) ADK PF00406.17 ETO27056.1 - 2.6e-24 85.8 0.0 4.5e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 ETO27056.1 - 5.6e-06 27.1 0.0 2.1e-05 25.3 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 ETO27056.1 - 4.6e-05 23.7 0.0 0.00014 22.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETO27056.1 - 0.00098 19.0 0.0 0.0052 16.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 ETO27056.1 - 0.0021 18.2 0.0 0.0065 16.6 0.0 1.9 2 0 0 2 2 2 1 RNA helicase AAA_16 PF13191.1 ETO27056.1 - 0.018 15.0 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ADK_lid PF05191.9 ETO27056.1 - 0.026 14.2 6.4 0.11 12.2 4.5 2.0 1 1 0 1 1 1 0 Adenylate kinase, active site lid Mg_chelatase PF01078.16 ETO27056.1 - 0.05 12.7 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 ETO27056.1 - 0.091 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 ETO27056.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NTP_transf_5 PF14907.1 ETO27056.1 - 0.12 11.7 0.1 0.26 10.6 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised nucleotidyltransferase ABC_tran PF00005.22 ETO27056.1 - 0.12 12.7 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 ETO27056.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Integrase_DNA PF02920.10 ETO27057.1 - 0.00087 18.6 1.8 0.00087 18.6 1.2 1.9 1 1 1 2 2 2 1 DNA binding domain of tn916 integrase IncA PF04156.9 ETO27057.1 - 0.014 14.9 1.3 0.016 14.8 0.4 1.3 1 1 0 1 1 1 0 IncA protein Rgp1 PF08737.5 ETO27057.1 - 0.038 13.0 4.1 0.042 12.9 2.9 1.0 1 0 0 1 1 1 0 Rgp1 KorB PF08535.5 ETO27057.1 - 0.042 14.0 0.9 1.5 9.0 0.0 2.4 2 0 0 2 2 2 0 KorB domain SPX PF03105.14 ETO27057.1 - 0.068 12.9 4.1 0.081 12.6 2.8 1.1 1 0 0 1 1 1 0 SPX domain DUF932 PF06067.6 ETO27057.1 - 0.085 12.1 0.7 0.11 11.8 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF932) M11L PF11099.3 ETO27057.1 - 0.16 11.6 2.9 0.21 11.2 2.0 1.2 1 0 0 1 1 1 0 Apoptosis regulator M11L like Tubulin PF00091.20 ETO27058.1 - 9.3e-38 130.2 0.0 1.5e-37 129.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO27058.1 - 1.1e-36 125.6 0.0 1.8e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain FAD_binding_2 PF00890.19 ETO27059.1 - 3.8e-71 240.1 0.0 5e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETO27059.1 - 1e-07 31.2 0.6 7e-07 28.4 0.4 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 ETO27059.1 - 1.9e-07 30.5 0.1 3.4e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETO27059.1 - 3e-05 23.9 0.7 3e-05 23.9 0.5 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 ETO27059.1 - 6.8e-05 21.9 2.3 0.00021 20.2 0.2 2.4 3 0 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.12 ETO27059.1 - 0.00019 20.6 0.2 0.0012 18.0 0.1 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 ETO27059.1 - 0.00052 19.9 6.7 0.0014 18.5 1.5 2.9 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 ETO27059.1 - 0.00063 18.9 0.0 0.00091 18.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 ETO27059.1 - 0.00075 18.0 0.5 0.00075 18.0 0.4 2.1 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.1 ETO27059.1 - 0.0014 18.7 0.1 0.0027 17.8 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETO27059.1 - 0.029 14.7 0.6 0.029 14.7 0.4 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 ETO27059.1 - 0.037 13.1 0.6 0.084 12.0 0.0 1.7 2 0 0 2 2 2 0 GMC oxidoreductase SBP_bac_1 PF01547.20 ETO27059.1 - 0.048 13.3 0.9 0.17 11.5 0.1 2.0 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein 3HCDH_N PF02737.13 ETO27059.1 - 0.053 13.1 0.5 0.089 12.4 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 ETO27059.1 - 0.17 10.7 0.5 0.26 10.1 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Tubulin PF00091.20 ETO27060.1 - 4.6e-60 203.1 0.0 2.2e-59 200.9 0.0 1.9 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO27060.1 - 1e-36 125.7 0.0 1.6e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Lipase_3 PF01764.20 ETO27060.1 - 0.0067 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Lipoprotein_Ltp PF07553.6 ETO27062.1 - 8.1 6.4 6.4 7.6 6.4 0.2 3.4 3 0 0 3 3 3 0 Host cell surface-exposed lipoprotein DivIVA PF05103.8 ETO27063.1 - 0.0048 16.9 1.5 0.0088 16.0 0.2 1.9 1 1 0 1 1 1 1 DivIVA protein DUF2383 PF09537.5 ETO27063.1 - 0.038 14.2 0.1 0.082 13.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) ICEA PF05315.6 ETO27063.1 - 0.089 12.0 1.9 0.18 11.0 1.3 1.5 1 1 1 2 2 2 0 ICEA Protein DUF4064 PF13273.1 ETO27064.1 - 0.0036 17.3 0.1 0.0064 16.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) DUF912 PF06024.7 ETO27064.1 - 0.039 14.0 0.9 0.066 13.2 0.6 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Glyco_transf_22 PF03901.12 ETO27065.1 - 9e-76 255.5 48.0 1.1e-75 255.2 33.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family NCA2 PF08637.5 ETO27067.1 - 0.0011 17.8 4.3 0.0058 15.5 1.5 2.1 1 1 1 2 2 2 2 ATP synthase regulation protein NCA2 Evr1_Alr PF04777.8 ETO27067.1 - 0.11 12.3 1.3 6.4 6.7 0.9 2.5 1 1 0 1 1 1 0 Erv1 / Alr family DUF2207 PF09972.4 ETO27068.1 - 0.2 10.1 1.6 0.24 9.9 1.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PGP_phosphatase PF09419.5 ETO27069.1 - 0.051 12.9 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase CW_binding_2 PF04122.7 ETO27070.1 - 0.037 14.2 0.1 0.12 12.6 0.1 1.8 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 Lipoprotein_10 PF03202.8 ETO27070.1 - 0.46 10.4 5.2 0.95 9.4 3.6 1.5 1 0 0 1 1 1 0 Putative mycoplasma lipoprotein, C-terminal region DUF972 PF06156.8 ETO27070.1 - 7.8 6.8 13.4 1.5 9.2 5.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) CAP_GLY PF01302.20 ETO27071.1 - 1.9e-20 72.3 0.4 3.6e-20 71.4 0.3 1.4 1 0 0 1 1 1 1 CAP-Gly domain DnaJ_CXXCXGXG PF00684.14 ETO27071.1 - 0.018 15.0 2.6 0.045 13.8 1.8 1.7 1 0 0 1 1 1 0 DnaJ central domain FAT PF02259.18 ETO27071.1 - 0.046 12.6 0.3 0.063 12.2 0.2 1.1 1 0 0 1 1 1 0 FAT domain zf-NADH-PPase PF09297.6 ETO27071.1 - 0.12 11.9 9.4 7.5 6.1 0.1 3.7 3 1 1 4 4 4 0 NADH pyrophosphatase zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 ETO27071.1 - 0.94 9.3 10.0 0.9 9.3 2.6 2.5 1 1 1 2 2 2 0 Transposase zinc-ribbon domain DUF329 PF03884.9 ETO27071.1 - 0.95 9.0 13.4 7.2 6.2 0.3 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF329) ZZ PF00569.12 ETO27071.1 - 1.4 8.5 8.0 6.4 6.4 5.5 2.0 1 1 0 1 1 1 0 Zinc finger, ZZ type Ribosomal_S27e PF01667.12 ETO27071.1 - 4.4 6.9 6.6 14 5.3 2.2 2.4 2 0 0 2 2 2 0 Ribosomal protein S27 C1_4 PF07975.7 ETO27071.1 - 6.1 6.9 12.3 20 5.2 6.2 2.5 1 1 1 2 2 2 0 TFIIH C1-like domain SLAM PF06214.6 ETO27072.1 - 0.056 13.3 0.3 0.075 12.9 0.2 1.2 1 0 0 1 1 1 0 Signaling lymphocytic activation molecule (SLAM) protein TORC_M PF12885.2 ETO27073.1 - 0.22 11.2 3.7 0.41 10.3 0.5 2.0 1 1 0 2 2 2 0 Transducer of regulated CREB activity middle domain Speriolin_C PF15059.1 ETO27074.1 - 0.0025 17.8 2.2 3.5 7.6 0.0 3.5 3 1 0 3 3 3 2 Speriolin C-terminus Hydrolase_3 PF08282.7 ETO27074.1 - 2.2 7.7 20.5 0.035 13.6 6.2 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Mucin PF01456.12 ETO27074.1 - 3.7 7.3 8.4 12 5.7 5.8 1.8 1 1 0 1 1 1 0 Mucin-like glycoprotein Bax1-I PF01027.15 ETO27075.1 - 0.0039 16.8 3.4 0.007 15.9 2.4 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 FA_desaturase PF00487.19 ETO27075.1 - 0.0051 16.2 4.8 0.011 15.2 3.3 1.5 1 0 0 1 1 1 1 Fatty acid desaturase Claudin_2 PF13903.1 ETO27075.1 - 0.0065 16.1 0.0 0.0065 16.1 0.0 2.4 2 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF3484 PF11983.3 ETO27075.1 - 3.9 8.3 9.4 0.68 10.8 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3484) Hex_IIIa PF02455.11 ETO27075.1 - 9.5 4.7 18.5 0.039 12.6 5.3 1.9 2 0 0 2 2 2 0 Hexon-associated protein (IIIa) Guanylate_cyc PF00211.15 ETO27076.1 - 1.1e-12 47.6 0.0 2.4e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Utp12 PF04003.7 ETO27076.1 - 0.071 13.0 0.0 0.79 9.6 0.0 2.3 2 0 0 2 2 2 0 Dip2/Utp12 Family PAPA-1 PF04795.7 ETO27076.1 - 0.11 13.2 3.2 0.4 11.4 1.9 2.2 2 0 0 2 2 2 0 PAPA-1-like conserved region MRP-S31 PF15433.1 ETO27076.1 - 1.3 8.3 11.1 2.1 7.6 7.7 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 ATP-sulfurylase PF01747.12 ETO27078.1 - 5.3e-73 244.8 1.0 5.1e-53 179.5 0.0 2.1 2 0 0 2 2 2 2 ATP-sulfurylase APS_kinase PF01583.15 ETO27078.1 - 8.8e-34 116.4 0.1 1.8e-33 115.4 0.0 1.5 2 0 0 2 2 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 ETO27078.1 - 3.1e-13 49.4 0.1 5.1e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain KTI12 PF08433.5 ETO27078.1 - 5.6e-06 25.7 0.0 8.8e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 ETO27078.1 - 4.7e-05 23.2 0.0 8.3e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETO27078.1 - 0.00013 22.3 0.0 0.00035 20.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO27078.1 - 0.0006 20.6 0.0 0.0017 19.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 ETO27078.1 - 0.0037 16.7 0.0 0.0075 15.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 ETO27078.1 - 0.0069 16.3 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 ETO27078.1 - 0.0091 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.1 ETO27078.1 - 0.015 15.2 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 ETO27078.1 - 0.017 14.2 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ArgK PF03308.11 ETO27078.1 - 0.027 13.2 0.0 0.048 12.4 0.0 1.3 1 0 0 1 1 1 0 ArgK protein MIT PF04212.13 ETO27078.1 - 0.085 12.7 0.0 0.57 10.0 0.0 2.1 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain AAA_22 PF13401.1 ETO27078.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 ETO27078.1 - 0.1 11.5 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 ETO27078.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain NAD_kinase PF01513.16 ETO27079.1 - 3.6e-10 39.0 0.0 4.8e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 ETO27079.1 - 0.015 14.6 0.2 0.035 13.5 0.0 1.7 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain ATP-synt_C PF00137.16 ETO27079.1 - 0.019 14.8 1.1 0.031 14.1 0.8 1.2 1 0 0 1 1 1 0 ATP synthase subunit C PRP38 PF03371.10 ETO27081.1 - 5.4e-57 192.1 1.6 5.4e-57 192.1 1.1 1.5 2 0 0 2 2 2 1 PRP38 family DUF2569 PF10754.4 ETO27082.1 - 0.048 13.8 0.1 0.073 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) GHL6 PF14871.1 ETO27082.1 - 0.073 13.1 0.0 1.7 8.6 0.0 2.1 1 1 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Nol1_Nop2_Fmu PF01189.12 ETO27083.1 - 3.9e-16 59.2 0.0 1.9e-12 47.1 0.0 2.6 2 1 0 2 2 2 2 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 ETO27083.1 - 0.00031 20.3 0.0 0.087 12.4 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 ETO27083.1 - 0.019 15.5 0.0 0.87 10.1 0.0 2.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 ETO27083.1 - 0.03 14.3 0.0 0.13 12.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 ETO27083.1 - 0.034 14.5 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Mating_C PF12737.2 ETO27083.1 - 0.24 10.2 3.0 0.33 9.7 2.1 1.1 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 FKBP_C PF00254.23 ETO27086.1 - 4.6e-18 65.0 0.0 9e-18 64.0 0.0 1.6 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase MAR_sialic_bdg PF10564.4 ETO27089.1 - 0.024 14.3 0.3 0.024 14.3 0.2 1.5 2 0 0 2 2 2 0 Sialic-acid binding micronemal adhesive repeat Di19_C PF14571.1 ETO27089.1 - 0.087 13.1 0.2 0.11 12.8 0.1 1.1 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal zf-TRM13_CCCH PF11722.3 ETO27089.1 - 1.7 8.0 7.9 3.8 6.9 5.5 1.6 1 1 0 1 1 1 0 CCCH zinc finger in TRM13 protein DcpS PF05652.7 ETO27090.1 - 0.011 16.1 5.6 0.17 12.2 0.2 2.1 2 0 0 2 2 2 0 Scavenger mRNA decapping enzyme (DcpS) N-terminal Herpes_env PF01673.13 ETO27090.1 - 0.029 12.9 1.4 0.034 12.7 0.2 1.5 1 1 1 2 2 2 0 Herpesvirus putative major envelope glycoprotein IncFII_repA PF02387.10 ETO27090.1 - 0.055 12.6 7.8 1.9 7.5 0.1 2.2 2 0 0 2 2 2 0 IncFII RepA protein family RPEL PF02755.10 ETO27090.1 - 0.086 12.1 0.4 0.086 12.1 0.3 4.1 4 0 0 4 4 4 0 RPEL repeat HTH_22 PF13309.1 ETO27090.1 - 0.37 10.5 2.6 29 4.5 0.1 3.0 3 0 0 3 3 3 0 HTH domain Metallophos_2 PF12850.2 ETO27092.1 - 0.097 12.5 0.0 0.15 11.8 0.0 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Pax2_C PF12403.3 ETO27094.1 - 0.047 13.3 0.2 0.13 11.8 0.2 1.7 1 0 0 1 1 1 0 Paired-box protein 2 C terminal SIR2 PF02146.12 ETO27095.1 - 1e-35 123.0 0.1 1.2e-35 122.8 0.0 1.0 1 0 0 1 1 1 1 Sir2 family DNA_ligase_ZBD PF03119.11 ETO27095.1 - 0.02 14.5 1.4 0.034 13.8 0.5 1.8 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Sgf11 PF08209.6 ETO27095.1 - 0.62 9.4 3.0 25 4.2 0.1 3.2 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) DZR PF12773.2 ETO27095.1 - 0.64 9.8 4.3 1.4 8.7 3.0 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_3 PF14369.1 ETO27095.1 - 0.68 9.9 3.9 0.77 9.8 1.2 2.2 2 1 0 2 2 2 0 zinc-finger DNA_RNApol_7kD PF03604.8 ETO27095.1 - 7.5 6.1 7.5 1.2e+02 2.2 3.7 2.8 2 1 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit PH PF00169.24 ETO27098.1 - 1.8e-10 40.9 0.1 1.8e-10 40.9 0.1 2.1 2 1 0 2 2 2 1 PH domain PH_3 PF14593.1 ETO27098.1 - 0.00028 20.7 0.3 0.0016 18.3 0.2 2.2 1 1 0 1 1 1 1 PH domain Mcp5_PH PF12814.2 ETO27098.1 - 0.0028 17.5 0.1 0.0059 16.5 0.1 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH_11 PF15413.1 ETO27098.1 - 0.0093 16.2 1.0 0.0093 16.2 0.7 2.7 2 2 0 2 2 2 1 Pleckstrin homology domain Acetyltransf_1 PF00583.19 ETO27100.1 - 5.2e-11 42.4 0.0 2e-10 40.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETO27100.1 - 2.7e-06 27.4 0.9 8.9e-06 25.7 0.6 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETO27100.1 - 6.3e-06 26.0 0.0 1.4e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 ETO27100.1 - 0.00026 20.8 0.4 0.00064 19.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 ETO27100.1 - 0.0015 18.7 0.0 0.0028 17.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 ETO27100.1 - 0.003 17.4 0.0 0.0079 16.0 0.0 1.7 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 ETO27100.1 - 0.008 16.2 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETO27100.1 - 0.012 15.3 0.0 0.037 13.7 0.0 1.7 2 0 0 2 2 2 0 FR47-like protein SIR2 PF02146.12 ETO27101.1 - 8.3e-05 22.3 0.6 0.00098 18.8 0.0 2.3 2 1 0 2 2 2 1 Sir2 family DUF3795 PF12675.2 ETO27101.1 - 0.25 11.5 2.6 0.51 10.5 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3795) C1_2 PF03107.11 ETO27101.1 - 0.65 10.1 3.3 1.3 9.1 2.3 1.6 1 0 0 1 1 1 0 C1 domain ZZ PF00569.12 ETO27101.1 - 0.91 9.1 7.7 0.65 9.5 3.3 2.3 2 1 0 2 2 2 0 Zinc finger, ZZ type WD40 PF00400.27 ETO27102.1 - 1.2e-38 129.6 5.5 2.2e-12 46.3 0.1 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 ETO27102.1 - 2.9e-08 33.6 0.0 0.004 16.8 0.0 2.8 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO27102.1 - 2.7e-05 22.5 0.1 0.046 11.8 0.0 2.9 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO27102.1 - 9.2e-05 20.9 0.1 0.2 9.8 0.0 2.7 1 1 2 3 3 3 3 Cytochrome D1 heme domain PD40 PF07676.7 ETO27102.1 - 0.00071 19.1 4.2 3.8 7.2 0.2 4.7 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO27102.1 - 0.0024 16.7 2.3 0.039 12.7 0.6 2.4 1 1 1 2 2 2 2 Nup133 N terminal like PQQ_2 PF13360.1 ETO27102.1 - 0.0041 16.6 0.1 1.1 8.6 0.0 2.3 1 1 2 3 3 3 2 PQQ-like domain Coatomer_WDAD PF04053.9 ETO27102.1 - 0.046 12.5 0.1 3.1 6.4 0.0 2.0 1 1 0 2 2 2 0 Coatomer WD associated region Vma12 PF11712.3 ETO27103.1 - 5.7e-05 22.8 1.8 0.0001 22.0 1.3 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase RED_N PF07808.8 ETO27103.1 - 0.0043 16.2 3.2 0.0053 16.0 2.2 1.1 1 0 0 1 1 1 1 RED-like protein N-terminal region Tic20 PF09685.5 ETO27103.1 - 1.3 9.0 9.7 4.6 7.2 1.5 2.6 1 1 1 2 2 2 0 Tic20-like protein Isochorismatase PF00857.15 ETO27104.1 - 4.1e-20 72.4 0.1 4.7e-20 72.2 0.1 1.1 1 0 0 1 1 1 1 Isochorismatase family DIL PF01843.14 ETO27105.1 - 8.2e-09 35.2 3.0 3.2e-08 33.3 2.1 2.1 1 0 0 1 1 1 1 DIL domain PBP1_TM PF14812.1 ETO27106.1 - 0.026 14.8 0.3 0.026 14.8 0.2 4.0 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GCIP PF13324.1 ETO27106.1 - 0.071 12.3 0.1 0.071 12.3 0.1 1.6 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting DUF3527 PF12043.3 ETO27106.1 - 0.47 9.9 10.1 0.56 9.6 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) MIP-T3 PF10243.4 ETO27106.1 - 0.64 8.4 28.3 0.81 8.0 19.6 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF3595 PF12166.3 ETO27106.1 - 6.5 5.4 9.1 8.6 5.0 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) Daxx PF03344.10 ETO27107.1 - 0.011 14.3 26.8 0.015 13.8 18.6 1.2 1 0 0 1 1 1 0 Daxx Family DUF2147 PF09917.4 ETO27107.1 - 0.098 12.9 0.1 0.098 12.9 0.0 2.7 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2147) DUF2890 PF11081.3 ETO27107.1 - 9.9 6.1 28.5 22 5.0 19.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) YjgP_YjgQ PF03739.9 ETO27110.1 - 0.14 10.8 0.5 0.2 10.3 0.3 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family C2 PF00168.25 ETO27111.1 - 1.7e-21 75.8 0.6 2.4e-21 75.3 0.0 1.5 2 0 0 2 2 2 1 C2 domain DUF4616 PF15394.1 ETO27111.1 - 0.04 12.9 0.2 0.046 12.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4616) Prog_receptor PF02161.10 ETO27111.1 - 0.22 10.3 2.2 0.26 10.0 1.5 1.0 1 0 0 1 1 1 0 Progesterone receptor YqfQ PF14181.1 ETO27111.1 - 0.68 9.9 6.3 0.92 9.5 4.4 1.2 1 0 0 1 1 1 0 YqfQ-like protein PBP_sp32 PF07222.7 ETO27111.1 - 6.1 5.9 11.1 8.9 5.3 7.7 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Fmp27_SW PF10305.4 ETO27113.1 - 0.021 15.2 0.1 0.036 14.4 0.1 1.4 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Upf2 PF04050.9 ETO27113.1 - 0.62 9.8 6.0 0.87 9.3 4.2 1.2 1 0 0 1 1 1 0 Up-frameshift suppressor 2 DSPc PF00782.15 ETO27114.1 - 1.4e-29 102.3 3.0 3.4e-29 101.0 0.3 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 ETO27114.1 - 7.8e-06 25.3 0.2 9.7e-06 25.0 0.2 1.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 ETO27114.1 - 0.04 12.8 2.8 0.047 12.5 2.0 1.2 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase FLYWCH PF04500.11 ETO27115.1 - 0.00038 20.2 4.9 0.041 13.7 0.0 3.1 3 0 0 3 3 3 2 FLYWCH zinc finger domain Nop14 PF04147.7 ETO27115.1 - 0.012 13.5 15.5 0.029 12.2 10.7 1.6 1 1 0 1 1 1 0 Nop14-like family TFIIA PF03153.8 ETO27115.1 - 0.039 13.8 19.2 0.0095 15.8 10.8 1.8 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit BSP_II PF05432.6 ETO27115.1 - 0.61 9.3 16.5 1.1 8.4 7.4 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Pkinase PF00069.20 ETO27117.1 - 1.4e-53 181.7 0.0 3.2e-53 180.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO27117.1 - 5e-36 124.1 0.0 1.2e-35 122.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO27117.1 - 4.9e-07 28.9 0.0 0.00052 19.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Methyltransf_31 PF13847.1 ETO27118.1 - 2.6e-09 36.8 0.2 4.7e-09 36.0 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO27118.1 - 4e-07 30.5 0.0 7.8e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 ETO27118.1 - 9.9e-05 22.0 0.4 0.00026 20.6 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETO27118.1 - 0.00092 19.5 0.0 0.0021 18.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO27118.1 - 0.0016 18.8 1.5 0.0022 18.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETO27118.1 - 0.044 13.4 0.1 0.13 11.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 ETO27118.1 - 0.048 13.0 0.0 0.43 9.9 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.7 ETO27118.1 - 0.098 13.1 0.1 0.74 10.3 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain DUF1886 PF09171.5 ETO27119.1 - 0.12 11.3 2.0 0.12 11.4 0.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1886) Mnd1 PF03962.10 ETO27119.1 - 0.31 10.6 6.1 0.38 10.4 4.2 1.1 1 0 0 1 1 1 0 Mnd1 family Exonuc_VII_L PF02601.10 ETO27119.1 - 7 5.7 7.4 8.1 5.5 5.1 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit WD40 PF00400.27 ETO27120.1 - 1.4e-22 78.6 10.4 2.1e-10 40.0 0.7 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO27120.1 - 0.0089 14.3 0.0 0.014 13.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome D1 heme domain Hira PF07569.6 ETO27120.1 - 0.16 11.1 2.1 1.2 8.2 0.0 2.8 2 1 1 3 3 3 0 TUP1-like enhancer of split DUF4598 PF15370.1 ETO27121.1 - 0.00064 19.9 1.8 0.0011 19.2 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4598) Baculo_p24 PF05073.7 ETO27121.1 - 0.0074 15.8 0.9 0.0084 15.6 0.6 1.1 1 0 0 1 1 1 1 Baculovirus P24 capsid protein Nif11 PF07862.6 ETO27121.1 - 0.019 14.9 0.1 0.03 14.2 0.1 1.4 1 0 0 1 1 1 0 Nitrogen fixation protein of unknown function XhlA PF10779.4 ETO27121.1 - 0.5 10.3 6.4 2 8.4 1.2 2.5 2 0 0 2 2 2 0 Haemolysin XhlA Citrate_synt PF00285.16 ETO27122.1 - 4.6e-30 104.5 0.0 6.3e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase ABC_tran PF00005.22 ETO27123.1 - 1.9e-16 60.5 0.1 4.4e-16 59.4 0.0 1.6 2 0 0 2 2 2 1 ABC transporter ABC_ATPase PF09818.4 ETO27123.1 - 7.9e-06 24.7 0.1 9.6e-06 24.4 0.1 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class SMC_N PF02463.14 ETO27123.1 - 1.2e-05 24.6 0.1 1.5e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 ETO27123.1 - 8e-05 22.4 1.0 0.0013 18.5 0.7 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 ETO27123.1 - 0.0025 17.8 0.0 0.0029 17.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 ETO27123.1 - 0.018 15.2 0.1 0.023 14.9 0.1 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 ETO27124.1 - 5.7e-06 26.2 0.3 1.7e-05 24.7 0.2 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 ETO27124.1 - 8.5e-06 25.0 0.3 2.4e-05 23.5 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SRP54 PF00448.17 ETO27124.1 - 0.0026 17.2 0.9 0.2 11.0 0.0 2.7 1 1 1 2 2 2 1 SRP54-type protein, GTPase domain AAA_33 PF13671.1 ETO27124.1 - 0.0095 15.8 0.1 0.03 14.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 ETO27124.1 - 0.03 14.5 0.2 0.12 12.5 0.1 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETO27124.1 - 0.053 13.4 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain BEX PF04538.7 ETO27124.1 - 0.1 12.7 0.1 0.1 12.7 0.1 2.8 4 0 0 4 4 4 0 Brain expressed X-linked like family ABC_tran PF00005.22 ETO27124.1 - 0.12 12.6 3.4 0.092 13.0 0.7 2.3 2 1 0 2 2 2 0 ABC transporter AAA_29 PF13555.1 ETO27124.1 - 0.14 11.6 0.0 0.36 10.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain V_ATPase_I PF01496.14 ETO27125.1 - 0.13 10.1 1.7 0.11 10.2 1.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pyrophosphatase PF00719.14 ETO27125.1 - 0.69 9.3 3.4 1.5 8.2 1.2 2.0 1 1 1 2 2 2 0 Inorganic pyrophosphatase CDC45 PF02724.9 ETO27128.1 - 0.00012 20.3 1.8 0.00012 20.3 1.3 2.1 2 0 0 2 2 2 1 CDC45-like protein DUF2457 PF10446.4 ETO27128.1 - 0.0031 16.3 54.9 0.051 12.2 13.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2457) Sigma70_ner PF04546.8 ETO27128.1 - 0.012 15.2 7.4 0.012 15.2 5.1 2.8 2 1 0 2 2 2 0 Sigma-70, non-essential region Glypican PF01153.14 ETO27128.1 - 0.13 10.8 9.7 0.12 10.8 2.8 2.2 2 0 0 2 2 2 0 Glypican CENP-T PF15511.1 ETO27128.1 - 0.45 9.7 28.4 0.11 11.6 8.6 2.1 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T SGT1 PF07093.6 ETO27128.1 - 1.7 6.9 30.1 1.8 6.8 10.1 2.1 2 0 0 2 2 2 0 SGT1 protein SPX PF03105.14 ETO27128.1 - 1.7 8.3 26.9 0.78 9.4 5.1 2.4 2 0 0 2 2 2 0 SPX domain TRAP_alpha PF03896.11 ETO27128.1 - 2.5 6.9 23.9 0.023 13.7 1.0 2.3 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit RRN3 PF05327.6 ETO27128.1 - 4.3 5.3 25.9 0.8 7.7 6.8 2.3 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 SQS_PSY PF00494.14 ETO27129.1 - 0.07 12.4 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Squalene/phytoene synthase CDC45 PF02724.9 ETO27130.1 - 1.9 6.4 13.6 2 6.3 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 ETO27130.1 - 2 6.2 21.3 2.1 6.1 14.8 1.0 1 0 0 1 1 1 0 Nop14-like family Raftlin PF15250.1 ETO27130.1 - 3.9 5.9 9.4 4.4 5.7 6.5 1.1 1 0 0 1 1 1 0 Raftlin Utp14 PF04615.8 ETO27130.1 - 5.9 4.9 20.3 6 4.9 14.1 1.0 1 0 0 1 1 1 0 Utp14 protein Tim54 PF11711.3 ETO27130.1 - 9.8 4.6 7.6 11 4.5 5.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NACHT PF05729.7 ETO27131.1 - 9.5e-10 38.3 0.0 3.7e-09 36.4 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 ETO27131.1 - 0.0011 19.1 0.1 0.0055 16.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ETO27131.1 - 0.32 11.8 4.6 0.33 11.7 0.0 3.5 3 0 0 3 3 3 0 AAA domain Muted PF14942.1 ETO27132.1 - 1.3 8.9 6.8 2.8 7.8 4.7 1.5 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein TPR_12 PF13424.1 ETO27133.1 - 1.3e-49 165.9 10.1 1.1e-20 73.3 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO27133.1 - 2e-30 104.2 17.3 1.1e-12 47.3 0.6 3.6 3 1 0 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETO27133.1 - 6.8e-27 91.9 33.5 2.3e-08 33.2 0.8 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO27133.1 - 4.7e-26 89.9 1.8 2.2e-07 30.5 0.0 4.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO27133.1 - 5.9e-23 78.9 26.4 1.4e-05 24.6 0.2 6.0 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_7 PF13176.1 ETO27133.1 - 1.1e-22 77.9 6.5 1.9e-05 24.1 0.0 5.7 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO27133.1 - 1.9e-21 74.1 31.6 9.6e-06 25.0 0.9 6.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 ETO27133.1 - 2.6e-12 45.9 10.8 0.066 13.4 0.0 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO27133.1 - 8e-11 41.5 0.2 0.024 15.2 0.0 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO27133.1 - 1.8e-09 37.4 4.7 1.4 9.4 0.1 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO27133.1 - 3.3e-09 37.1 3.0 0.00078 20.0 0.1 4.0 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO27133.1 - 1.1e-06 28.8 2.2 0.028 14.7 0.3 3.1 2 1 2 4 4 4 3 Tetratricopeptide repeat PPR PF01535.15 ETO27133.1 - 1.3e-05 24.8 1.6 0.72 9.9 0.0 5.2 4 0 0 4 4 4 1 PPR repeat TPR_3 PF07720.7 ETO27133.1 - 0.0009 18.9 12.4 0.078 12.8 0.0 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat PDR_assoc PF08370.6 ETO27133.1 - 0.0013 18.2 1.0 0.0037 16.7 0.7 1.8 1 0 0 1 1 1 1 Plant PDR ABC transporter associated SHNi-TPR PF10516.4 ETO27133.1 - 0.0044 16.2 0.0 0.31 10.3 0.0 2.9 2 0 0 2 2 2 1 SHNi-TPR MIT PF04212.13 ETO27133.1 - 0.017 14.9 15.1 3.8 7.4 0.0 5.4 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain RMF PF04957.7 ETO27133.1 - 0.084 12.5 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Ribosome modulation factor PPR_2 PF13041.1 ETO27133.1 - 2.2 8.3 0.0 2.2 8.3 0.0 4.7 6 0 0 6 6 5 0 PPR repeat family PrsW-protease PF13367.1 ETO27134.1 - 4.2e-13 48.9 6.8 4.9e-13 48.6 4.7 1.2 1 0 0 1 1 1 1 Protease prsW family UPF1_Zn_bind PF09416.5 ETO27135.1 - 0.54 9.8 4.1 0.2 11.2 0.6 1.8 1 1 1 2 2 2 0 RNA helicase (UPF2 interacting domain) Rad10 PF03834.9 ETO27135.1 - 1.1 8.9 7.9 15 5.3 0.5 3.1 1 1 1 2 2 2 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Methyltransf_10 PF05971.7 ETO27136.1 - 4.5e-45 154.0 9.4 7.7e-28 97.4 2.0 3.0 1 1 1 2 2 2 2 Protein of unknown function (DUF890) Methyltransf_31 PF13847.1 ETO27136.1 - 0.00072 19.1 0.3 0.0015 18.1 0.2 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 ETO27136.1 - 0.0012 17.8 0.7 0.0012 17.8 0.5 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_18 PF12847.2 ETO27136.1 - 0.017 15.6 0.0 0.036 14.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Cyclin_C PF02984.14 ETO27137.1 - 1.7e-10 40.8 0.1 2.2e-10 40.5 0.1 1.1 1 0 0 1 1 1 1 Cyclin, C-terminal domain Sin_N PF04801.8 ETO27138.1 - 1.4 7.6 14.5 1.9 7.2 10.1 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region SOBP PF15279.1 ETO27138.1 - 3.2 8.0 10.0 3.9 7.7 6.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Herpes_BLLF1 PF05109.8 ETO27139.1 - 0.097 10.6 17.5 0.12 10.2 12.1 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) 2-oxoacid_dh PF00198.18 ETO27140.1 - 1.1e-73 247.3 1.0 1.1e-73 247.3 0.1 1.4 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Sec62 PF03839.11 ETO27140.1 - 9.6 5.5 8.5 16 4.8 5.9 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 zf-SAP30 PF13866.1 ETO27141.1 - 0.055 13.1 0.5 0.11 12.1 0.3 1.5 1 0 0 1 1 1 0 SAP30 zinc-finger Pkinase PF00069.20 ETO27141.1 - 0.065 12.3 0.0 0.083 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain CGGC PF08821.6 ETO27141.1 - 2.3 8.3 8.7 0.13 12.3 1.1 2.1 1 1 1 2 2 2 0 CGGC domain Apc4_WD40 PF12894.2 ETO27142.1 - 0.015 14.8 0.0 0.06 12.8 0.0 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Agouti PF05039.7 ETO27142.1 - 0.83 10.0 5.1 0.17 12.2 0.3 2.1 2 0 0 2 2 2 0 Agouti protein SPRY PF00622.23 ETO27144.1 - 0.0045 17.0 0.5 0.0086 16.1 0.3 1.7 1 1 0 1 1 1 1 SPRY domain Herpes_UL37_1 PF03970.8 ETO27145.1 - 0.014 14.2 0.8 0.017 13.9 0.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL37 tegument protein HATPase_c_5 PF14501.1 ETO27145.1 - 0.048 13.3 0.3 0.073 12.7 0.2 1.3 1 0 0 1 1 1 0 GHKL domain UPF0066 PF01980.11 ETO27146.1 - 2.2e-21 76.0 0.2 3.9e-21 75.2 0.2 1.4 1 0 0 1 1 1 1 Uncharacterised protein family UPF0066 LRR_4 PF12799.2 ETO27147.1 - 3.1e-19 68.1 16.3 5.6e-08 32.2 3.8 4.5 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO27147.1 - 3.6e-11 42.6 20.8 1.6e-07 30.9 4.6 3.6 3 1 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 ETO27147.1 - 3.9e-08 32.2 20.7 0.37 11.0 0.1 6.3 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_6 PF13516.1 ETO27147.1 - 5.2e-05 22.9 16.4 0.079 13.0 0.1 6.3 3 2 2 5 5 5 2 Leucine Rich repeat LRR_7 PF13504.1 ETO27147.1 - 0.00056 19.6 14.1 18 6.0 0.0 6.3 5 1 0 5 5 5 0 Leucine rich repeat DUF2413 PF10310.4 ETO27147.1 - 0.0012 17.7 14.4 0.0019 17.0 10.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) LRR_9 PF14580.1 ETO27147.1 - 0.024 14.2 9.9 0.024 14.2 1.2 3.1 2 1 2 4 4 4 0 Leucine-rich repeat Ndc1_Nup PF09531.5 ETO27147.1 - 0.11 10.8 14.2 0.17 10.2 9.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PLRV_ORF5 PF01690.12 ETO27147.1 - 0.52 9.4 22.4 0.74 8.8 15.5 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Macoilin PF09726.4 ETO27147.1 - 0.93 7.7 28.4 1.2 7.2 19.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Gag_spuma PF03276.9 ETO27147.1 - 3.9 5.6 17.7 5.3 5.2 12.3 1.1 1 0 0 1 1 1 0 Spumavirus gag protein RR_TM4-6 PF06459.7 ETO27147.1 - 4.9 6.9 21.4 7.6 6.3 14.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sigma70_ner PF04546.8 ETO27148.1 - 0.013 15.1 13.0 0.015 14.8 9.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region YL1 PF05764.8 ETO27148.1 - 0.019 14.5 21.8 0.023 14.2 15.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Daxx PF03344.10 ETO27148.1 - 0.02 13.3 24.2 0.02 13.3 16.8 1.0 1 0 0 1 1 1 0 Daxx Family Cwf_Cwc_15 PF04889.7 ETO27148.1 - 0.092 12.4 19.5 0.12 12.0 13.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 ETO27148.1 - 0.33 8.8 23.8 0.39 8.5 16.5 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2890 PF11081.3 ETO27148.1 - 0.42 10.6 15.1 0.53 10.3 10.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Merozoite_SPAM PF07133.6 ETO27148.1 - 0.67 9.8 29.6 0.86 9.4 20.5 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) HSP90 PF00183.13 ETO27148.1 - 0.7 8.2 18.9 0.77 8.0 13.1 1.1 1 0 0 1 1 1 0 Hsp90 protein SDA1 PF05285.7 ETO27148.1 - 0.74 9.0 22.7 0.81 8.9 15.7 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 ETO27148.1 - 2 6.3 17.5 2.4 6.1 12.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Mem_trans PF03547.13 ETO27148.1 - 3.4 5.8 10.5 3.9 5.6 7.3 1.1 1 0 0 1 1 1 0 Membrane transport protein Sin_N PF04801.8 ETO27148.1 - 3.9 6.2 13.4 4.6 5.9 9.3 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region DUF506 PF04720.7 ETO27148.1 - 5.1 6.6 9.7 6.8 6.2 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Ycf1 PF05758.7 ETO27148.1 - 5.6 4.5 16.4 6.1 4.4 11.4 1.0 1 0 0 1 1 1 0 Ycf1 TMEM51 PF15345.1 ETO27148.1 - 8.8 5.9 11.0 10 5.7 7.6 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 TLP-20 PF06088.6 ETO27150.1 - 0.0039 16.8 0.9 0.0059 16.2 0.6 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) TRAP_alpha PF03896.11 ETO27150.1 - 0.025 13.6 1.5 0.033 13.1 1.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2457 PF10446.4 ETO27150.1 - 0.078 11.6 10.3 0.096 11.3 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Robl_LC7 PF03259.12 ETO27150.1 - 0.087 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Roadblock/LC7 domain Peptidase_S9 PF00326.16 ETO27151.1 - 0.0025 17.0 0.1 0.0067 15.6 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.6 ETO27151.1 - 0.02 14.6 0.1 0.25 11.0 0.0 2.2 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Phage_T4_Ndd PF06591.6 ETO27151.1 - 0.046 13.3 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) WD40 PF00400.27 ETO27152.1 - 0.034 14.0 2.2 15 5.6 0.0 3.7 3 0 0 3 3 3 0 WD domain, G-beta repeat K_trans PF02705.11 ETO27152.1 - 0.1 10.9 0.1 0.17 10.1 0.0 1.3 1 0 0 1 1 1 0 K+ potassium transporter ETRAMP PF09716.5 ETO27152.1 - 3.5 7.6 9.1 2.1 8.3 2.2 3.4 4 0 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) Menin PF05053.8 ETO27153.1 - 2.6e-05 22.6 1.0 4.8e-05 21.7 0.7 1.5 1 0 0 1 1 1 1 Menin DUF2975 PF11188.3 ETO27154.1 - 0.0027 17.4 0.0 0.004 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2975) DUF1645 PF07816.6 ETO27154.1 - 1.4 9.3 11.6 0.59 10.5 6.5 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1645) zf-TRAF PF02176.13 ETO27155.1 - 9.4e-10 38.7 12.8 5e-08 33.2 4.7 2.4 1 1 1 2 2 2 2 TRAF-type zinc finger Kelch_3 PF13415.1 ETO27155.1 - 0.0023 18.0 0.0 0.016 15.3 0.0 2.5 3 0 0 3 3 3 1 Galactose oxidase, central domain NACHT PF05729.7 ETO27156.1 - 1.7e-10 40.8 0.1 3.7e-10 39.6 0.0 1.6 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 ETO27156.1 - 9.7e-05 22.5 0.1 0.00046 20.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain RelA_SpoT PF04607.12 ETO27156.1 - 0.00017 21.5 1.3 0.00017 21.5 0.9 2.4 3 0 0 3 3 3 1 Region found in RelA / SpoT proteins AAA_18 PF13238.1 ETO27156.1 - 0.0033 17.7 4.0 0.012 15.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain L1R_F9L PF02442.12 ETO27156.1 - 0.0039 16.6 5.5 0.0039 16.6 3.8 1.9 2 0 0 2 2 2 1 Lipid membrane protein of large eukaryotic DNA viruses DUF912 PF06024.7 ETO27156.1 - 0.0048 16.9 4.3 0.011 15.7 3.0 1.6 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3753 PF12575.3 ETO27156.1 - 0.016 14.9 7.5 0.041 13.6 5.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) AAA_16 PF13191.1 ETO27156.1 - 0.047 13.6 0.1 0.16 11.9 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain ABC2_membrane_3 PF12698.2 ETO27156.1 - 0.087 11.8 7.4 0.052 12.5 3.7 1.6 2 0 0 2 2 2 0 ABC-2 family transporter protein EVI2A PF05399.6 ETO27156.1 - 0.11 11.6 2.1 0.21 10.8 1.4 1.4 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) WD40 PF00400.27 ETO27157.1 - 5.5e-174 558.6 46.8 6.8e-15 54.2 0.1 14.2 14 0 0 14 14 14 14 WD domain, G-beta repeat Nup160 PF11715.3 ETO27157.1 - 2.2e-11 42.5 25.5 0.056 11.5 0.1 9.2 1 1 4 7 7 7 6 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO27157.1 - 4.7e-09 35.0 2.6 2.8 6.1 0.0 6.8 1 1 8 9 9 9 7 Cytochrome D1 heme domain Pentapeptide PF00805.17 ETO27157.1 - 2e-08 33.2 2.7 3.6e-08 32.4 1.9 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) DUF1258 PF06869.7 ETO27157.1 - 8.4e-08 31.6 26.4 0.091 11.8 0.2 8.6 4 3 6 10 10 10 6 Protein of unknown function (DUF1258) PD40 PF07676.7 ETO27157.1 - 8.5e-06 25.3 13.1 1.4 8.7 0.1 8.2 9 0 0 9 9 9 2 WD40-like Beta Propeller Repeat Pentapeptide_4 PF13599.1 ETO27157.1 - 9.8e-06 25.2 0.4 5.6e-05 22.8 0.3 2.0 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Proteasome_A_N PF10584.4 ETO27157.1 - 2.1e-05 23.7 10.8 9.7 5.6 0.0 8.8 10 0 0 10 10 10 1 Proteasome subunit A N-terminal signature Pentapeptide_3 PF13576.1 ETO27157.1 - 0.00013 21.7 3.3 0.0002 21.1 0.4 2.9 2 1 0 2 2 2 1 Pentapeptide repeats (9 copies) TFIIH_BTF_p62_N PF08567.6 ETO27157.1 - 0.012 15.3 0.2 19 4.9 0.0 5.1 6 1 0 6 6 6 0 TFIIH p62 subunit, N-terminal domain WD40 PF00400.27 ETO27158.1 - 2.6e-36 122.1 26.9 2.5e-10 39.8 0.1 7.1 7 1 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO27158.1 - 0.00018 19.8 0.6 0.0084 14.2 0.0 3.0 1 1 1 2 2 2 1 Nucleoporin Nup120/160 GSDH PF07995.6 ETO27159.1 - 7.2e-12 45.0 0.1 1e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase PS_Dcarbxylase PF02666.10 ETO27160.1 - 1.2e-48 165.0 0.0 1.9e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase EF-hand_6 PF13405.1 ETO27161.1 - 2.8e-09 36.0 0.1 0.0018 18.0 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 ETO27161.1 - 1.6e-05 24.9 1.0 0.0026 17.8 0.2 2.0 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 ETO27161.1 - 0.00053 19.0 0.6 0.049 12.9 0.0 2.8 2 1 0 2 2 2 1 EF hand Parathyroid PF01279.12 ETO27163.1 - 0.097 13.3 0.8 0.14 12.8 0.6 1.3 1 0 0 1 1 1 0 Parathyroid hormone family RabGAP-TBC PF00566.13 ETO27164.1 - 3.1e-06 26.8 0.3 3.1e-06 26.8 0.2 4.5 4 1 0 4 4 4 2 Rab-GTPase-TBC domain MFS_1 PF07690.11 ETO27165.1 - 0.047 12.3 1.1 0.06 12.0 0.8 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily ABC2_membrane PF01061.19 ETO27167.1 - 2.4e-42 144.4 22.6 2.4e-42 144.4 15.6 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 ETO27167.1 - 1.1e-08 34.5 28.0 3.7e-08 32.8 19.4 2.0 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.2 ETO27167.1 - 0.0026 16.6 16.8 0.1 11.4 11.6 2.3 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.22 ETO27168.1 - 1.4e-10 41.5 3.5 2.9e-10 40.5 0.2 2.4 3 0 0 3 3 3 1 ABC transporter GSH-S_ATP PF02955.11 ETO27169.1 - 0.047 12.8 0.0 4.4 6.3 0.0 2.5 2 0 0 2 2 2 0 Prokaryotic glutathione synthetase, ATP-grasp domain CENP-C_C PF11699.3 ETO27170.1 - 1.8e-07 31.0 0.1 4.8e-07 29.6 0.1 1.6 1 1 0 1 1 1 1 Mif2/CENP-C like Glyco_hydro_31 PF01055.21 ETO27171.1 - 4.5e-29 101.5 0.6 4.5e-29 101.5 0.4 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 DUF4191 PF13829.1 ETO27172.1 - 1.3 8.0 10.1 0.28 10.2 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) G6B PF15096.1 ETO27173.1 - 0.012 15.1 0.3 0.048 13.1 0.2 2.1 1 0 0 1 1 1 0 G6B family Actin PF00022.14 ETO27174.1 - 1.5e-79 267.3 0.0 1.8e-79 267.0 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 ETO27174.1 - 0.016 13.8 0.0 0.062 11.8 0.0 1.7 1 1 0 1 1 1 0 MreB/Mbl protein XK-related PF09815.4 ETO27175.1 - 6.3 5.7 14.6 0.04 12.9 1.6 2.0 1 1 1 2 2 2 0 XK-related protein RicinB_lectin_2 PF14200.1 ETO27176.1 - 9.8e-19 67.6 0.0 1e-11 45.0 0.0 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 ETO27176.1 - 2.4e-06 27.5 0.2 3.3e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain DUF3899 PF13038.1 ETO27177.1 - 0.25 11.5 6.4 1.2 9.3 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Ras PF00071.17 ETO27178.1 - 3.6e-61 205.2 1.4 4.2e-61 205.0 1.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO27178.1 - 4.1e-19 69.2 0.1 6.6e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO27178.1 - 5.2e-18 64.8 0.2 5.9e-18 64.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO27178.1 - 5.1e-07 29.3 0.5 2.9e-06 26.8 0.3 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 ETO27178.1 - 9.2e-06 24.9 0.1 1.1e-05 24.6 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 ETO27178.1 - 4.4e-05 22.7 0.1 5.3e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 ETO27178.1 - 0.00018 21.4 0.0 0.00034 20.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 ETO27178.1 - 0.014 15.4 0.0 0.031 14.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETO27178.1 - 0.019 14.9 0.1 0.043 13.7 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 ETO27178.1 - 0.057 13.3 0.0 0.13 12.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 ETO27178.1 - 0.073 12.3 0.0 2 7.6 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B cobW PF02492.14 ETO27178.1 - 0.095 12.1 0.1 2.5 7.4 0.0 2.2 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain KSR1-SAM PF13543.1 ETO27179.1 - 0.0011 18.7 7.2 0.006 16.3 0.0 3.4 2 1 1 3 3 3 2 SAM like domain present in kinase suppressor RAS 1 RelA_SpoT PF04607.12 ETO27179.1 - 1.1 9.2 8.2 4.5 7.3 0.4 3.0 1 1 2 3 3 3 0 Region found in RelA / SpoT proteins WD40 PF00400.27 ETO27180.1 - 3e-13 49.1 5.3 1.6e-05 24.5 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat RNA_pol_Rpb1_5 PF04998.12 ETO27180.1 - 0.052 12.8 2.9 0.092 11.9 2.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 PQQ_3 PF13570.1 ETO27180.1 - 0.067 13.4 1.0 1.5 9.1 0.0 3.3 4 0 0 4 4 4 0 PQQ-like domain Myc_N PF01056.13 ETO27180.1 - 0.6 9.2 12.9 6.8 5.7 6.7 2.4 2 0 0 2 2 2 0 Myc amino-terminal region CDC45 PF02724.9 ETO27180.1 - 1.6 6.6 11.0 1 7.3 4.1 2.0 2 0 0 2 2 2 0 CDC45-like protein CENP-T PF15511.1 ETO27180.1 - 4.4 6.4 13.1 19 4.3 0.0 2.1 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T SIT PF15330.1 ETO27181.1 - 0.084 13.0 0.3 0.52 10.4 0.0 2.2 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT DUF3981 PF13139.1 ETO27181.1 - 6.3 6.8 6.9 4.1 7.4 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3981) Phosphodiest PF01663.17 ETO27182.1 - 3.1e-08 33.3 0.3 1.3e-05 24.7 0.1 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 ETO27182.1 - 0.004 16.4 0.0 0.2 10.8 0.0 2.2 1 1 1 2 2 2 2 Sulfatase POX PF07526.6 ETO27183.1 - 0.016 15.4 5.5 0.85 9.8 0.4 2.5 2 0 0 2 2 2 0 Associated with HOX Cellulose_synt PF03552.9 ETO27183.1 - 0.046 12.0 0.1 0.046 12.0 0.1 1.7 2 0 0 2 2 2 0 Cellulose synthase Elf1 PF05129.8 ETO27183.1 - 0.1 12.3 1.6 0.3 10.8 1.1 1.8 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like DUF2076 PF09849.4 ETO27183.1 - 4.4 7.2 8.6 0.79 9.7 1.1 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2076) Kelch_6 PF13964.1 ETO27184.1 - 0.0025 17.9 0.5 0.27 11.4 0.0 3.2 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 ETO27184.1 - 0.025 14.5 0.1 33 4.5 0.0 3.5 3 0 0 3 3 3 0 Kelch motif Kelch_3 PF13415.1 ETO27184.1 - 0.079 13.1 0.1 2.7 8.2 0.0 3.3 4 0 0 4 4 4 0 Galactose oxidase, central domain UQ_con PF00179.21 ETO27185.1 - 9.7e-20 70.4 0.2 1.3e-19 70.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TRAPP PF04051.11 ETO27186.1 - 2.9e-30 104.7 0.2 4.3e-30 104.2 0.1 1.3 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component SNARE PF05739.14 ETO27187.1 - 9.5e-08 31.6 0.3 9.5e-08 31.6 0.2 2.0 1 1 1 2 2 2 1 SNARE domain ApoLp-III PF07464.6 ETO27187.1 - 0.0067 16.4 1.9 0.011 15.7 0.6 1.7 1 1 1 2 2 2 1 Apolipophorin-III precursor (apoLp-III) CCDC155 PF14662.1 ETO27187.1 - 0.018 14.6 0.2 0.021 14.4 0.1 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DUF740 PF05340.7 ETO27187.1 - 0.054 11.8 0.8 0.059 11.7 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Ion_trans PF00520.26 ETO27187.1 - 0.056 12.6 0.1 0.075 12.2 0.0 1.1 1 0 0 1 1 1 0 Ion transport protein MCPsignal PF00015.16 ETO27187.1 - 0.056 12.9 0.0 0.068 12.7 0.0 1.1 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Foamy_virus_ENV PF03408.9 ETO27187.1 - 0.089 10.3 1.7 0.13 9.7 1.2 1.3 1 1 0 1 1 1 0 Foamy virus envelope protein Toxin_10 PF05431.6 ETO27187.1 - 0.15 11.7 0.4 0.26 10.8 0.2 1.4 1 1 0 1 1 1 0 Insecticidal Crystal Toxin, P42 DUF3138 PF11336.3 ETO27188.1 - 0.045 11.9 0.9 0.065 11.3 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Lactate_perm PF02652.9 ETO27188.1 - 0.19 10.1 0.0 0.27 9.7 0.0 1.1 1 0 0 1 1 1 0 L-lactate permease SSP160 PF06933.6 ETO27188.1 - 0.98 7.3 6.2 0.12 10.3 1.2 1.6 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 IBR PF01485.16 ETO27190.1 - 4e-11 42.6 8.9 4e-11 42.6 6.1 2.8 3 0 0 3 3 3 2 IBR domain Med28 PF11594.3 ETO27191.1 - 0.065 13.4 1.8 5.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Mediator complex subunit 28 UQ_con PF00179.21 ETO27192.1 - 3.7e-17 62.0 0.3 4.8e-17 61.7 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF4220 PF13968.1 ETO27195.1 - 0.00021 20.5 2.4 0.00026 20.2 0.9 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4220) DUF1576 PF07613.6 ETO27195.1 - 0.0028 17.1 0.7 0.0052 16.3 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1576) DUF2306 PF10067.4 ETO27195.1 - 0.016 15.3 1.3 0.016 15.3 0.9 2.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2306) PEN-2 PF10251.4 ETO27195.1 - 0.28 11.4 0.1 0.28 11.4 0.1 3.2 2 1 2 4 4 4 0 Presenilin enhancer-2 subunit of gamma secretase CT47 PF15623.1 ETO27196.1 - 0.0044 16.8 14.0 0.0052 16.5 9.7 1.1 1 0 0 1 1 1 1 Cancer/testis gene family 47 RR_TM4-6 PF06459.7 ETO27196.1 - 0.13 12.1 19.5 0.15 11.9 13.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2201_N PF13203.1 ETO27196.1 - 0.49 9.5 12.0 0.62 9.1 8.3 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain DDHD PF02862.12 ETO27196.1 - 1.1 8.9 15.8 1.5 8.5 10.9 1.3 1 0 0 1 1 1 0 DDHD domain Dsh_C PF12316.3 ETO27196.1 - 1.9 8.5 10.0 3 7.9 6.9 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal MIP-T3 PF10243.4 ETO27196.1 - 4.8 5.5 41.4 6.2 5.1 28.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1510 PF07423.6 ETO27196.1 - 10 5.4 32.2 13 5.0 22.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TPR_12 PF13424.1 ETO27197.1 - 8.3e-61 201.8 4.2 2.1e-18 66.0 0.5 5.2 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETO27197.1 - 7e-40 134.5 41.4 1.3e-14 53.5 3.5 5.3 2 1 5 7 7 7 7 TPR repeat TPR_1 PF00515.23 ETO27197.1 - 3.2e-34 115.1 34.7 1.7e-08 33.6 1.0 7.9 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_10 PF13374.1 ETO27197.1 - 1.3e-32 110.7 0.0 2.4e-07 30.4 0.0 6.9 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.1 ETO27197.1 - 1.5e-30 102.5 9.8 9.3e-07 28.1 0.0 8.2 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETO27197.1 - 1.1e-29 99.9 19.7 2.8e-06 26.8 0.3 8.2 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETO27197.1 - 2e-24 83.5 37.6 6.5e-07 28.6 1.9 8.2 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.1 ETO27197.1 - 2.6e-13 49.0 9.1 0.012 15.7 0.1 6.6 5 1 0 5 5 5 3 Tetratricopeptide repeat MIT PF04212.13 ETO27197.1 - 3.5e-09 36.4 10.6 0.00058 19.6 0.1 6.2 7 0 0 7 7 7 1 MIT (microtubule interacting and transport) domain TPR_16 PF13432.1 ETO27197.1 - 8.2e-09 35.9 0.0 0.029 15.0 0.0 5.2 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO27197.1 - 1.6e-08 34.4 7.3 2.3 8.8 0.1 7.1 8 1 0 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO27197.1 - 5.8e-08 32.9 0.5 0.031 14.6 0.0 4.6 4 1 0 4 4 4 1 Tetratricopeptide repeat SNAP PF14938.1 ETO27197.1 - 6.7e-08 32.0 5.4 1.9e-05 23.9 0.1 3.4 2 1 1 3 3 3 1 Soluble NSF attachment protein, SNAP Apc3 PF12895.2 ETO27197.1 - 1.6e-07 31.3 17.5 0.0038 17.3 1.4 4.5 2 2 3 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 ETO27197.1 - 1.7e-06 28.1 0.0 22 6.0 0.0 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat Sel1 PF08238.7 ETO27197.1 - 0.0013 19.3 9.0 6.4 7.5 0.1 5.5 6 0 0 6 6 5 1 Sel1 repeat SHNi-TPR PF10516.4 ETO27197.1 - 0.0046 16.1 4.5 17 4.7 0.0 5.1 7 0 0 7 7 7 0 SHNi-TPR DUF627 PF04781.7 ETO27197.1 - 0.0057 16.2 7.1 5.5 6.6 0.0 5.2 2 1 3 5 5 5 1 Protein of unknown function (DUF627) TPR_5 PF12688.2 ETO27197.1 - 0.0081 16.1 0.0 0.62 10.1 0.0 3.2 2 1 1 3 3 3 1 Tetratrico peptide repeat PPR PF01535.15 ETO27197.1 - 0.012 15.5 3.8 11 6.2 0.1 5.5 5 0 0 5 5 5 0 PPR repeat TPR_3 PF07720.7 ETO27197.1 - 0.013 15.2 30.7 0.073 12.8 0.1 8.0 9 0 0 9 9 9 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO27197.1 - 1.6 8.6 16.2 1.3 8.9 0.1 5.4 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat WD40 PF00400.27 ETO27198.1 - 6.5e-34 114.5 13.4 6.9e-11 41.6 0.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO27198.1 - 1.9e-08 32.9 2.8 0.00033 18.9 0.3 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 HARP PF07443.8 ETO27198.1 - 0.15 11.4 0.9 5.1 6.5 0.1 2.9 3 0 0 3 3 3 0 HepA-related protein (HARP) Cation_efflux PF01545.16 ETO27199.1 - 0.0011 18.1 2.6 0.0014 17.7 1.8 1.1 1 0 0 1 1 1 1 Cation efflux family Trypsin_2 PF13365.1 ETO27200.1 - 6.9e-15 55.0 0.0 3.1e-11 43.3 0.0 2.8 2 1 0 2 2 2 2 Trypsin-like peptidase domain Inositol_P PF00459.20 ETO27201.1 - 1e-14 54.4 0.0 2.3e-12 46.7 0.0 3.0 2 1 1 3 3 3 1 Inositol monophosphatase family Saccharop_dh PF03435.13 ETO27201.1 - 6.8e-09 35.1 2.2 1.1e-08 34.5 0.1 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 ETO27201.1 - 0.15 12.0 0.1 0.55 10.2 0.1 1.9 1 1 0 1 1 1 0 NADH(P)-binding HATPase_c_2 PF13581.1 ETO27201.1 - 0.18 11.5 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain NACHT PF05729.7 ETO27202.1 - 6.6e-07 29.1 0.1 1.5e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETO27202.1 - 1.4e-05 25.2 0.4 3.3e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 ETO27202.1 - 2.3e-05 23.3 1.4 4.3e-05 22.5 1.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 ETO27202.1 - 0.00013 22.0 0.0 0.00035 20.5 0.0 1.7 1 1 1 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 ETO27202.1 - 0.0057 15.8 0.0 0.013 14.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 DAP3 PF10236.4 ETO27202.1 - 0.022 13.7 0.0 0.044 12.7 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Arch_ATPase PF01637.13 ETO27202.1 - 0.023 14.4 0.3 0.058 13.0 0.2 1.7 1 1 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 ETO27202.1 - 0.031 14.1 0.1 0.12 12.3 0.1 2.0 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 ETO27202.1 - 0.046 14.2 0.1 0.23 11.9 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein Lyase_1 PF00206.15 ETO27203.1 - 1.8e-79 267.2 0.0 3.9e-55 187.2 0.0 2.0 2 0 0 2 2 2 2 Lyase FumaraseC_C PF10415.4 ETO27204.1 - 2.8e-28 97.7 0.1 4e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 Fumarase C C-terminus Lyase_1 PF00206.15 ETO27204.1 - 9.3e-07 28.3 0.6 2.1e-06 27.1 0.4 1.6 1 0 0 1 1 1 1 Lyase G-alpha PF00503.15 ETO27204.1 - 0.043 12.4 0.0 0.044 12.4 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit eIF-3c_N PF05470.7 ETO27205.1 - 0.00058 18.0 1.9 0.00074 17.7 1.3 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus C-C_Bond_Lyase PF15617.1 ETO27205.1 - 0.0071 15.2 0.1 0.0084 14.9 0.0 1.1 1 0 0 1 1 1 1 C-C_Bond_Lyase of the TIM-Barrel fold SHS2_Rpb7-N PF03876.12 ETO27206.1 - 2.5e-11 43.5 0.0 4e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 ETO27206.1 - 1.3e-07 31.6 0.0 5.2e-07 29.6 0.0 1.9 1 1 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 ETO27206.1 - 0.0073 16.4 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 Pyrophosphatase PF00719.14 ETO27208.1 - 1.5e-26 92.7 0.0 1.6e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Prominin PF05478.6 ETO27209.1 - 3.6 4.9 12.0 0.18 9.3 1.3 2.2 2 0 0 2 2 2 0 Prominin COMPASS-Shg1 PF05205.7 ETO27210.1 - 0.87 9.9 7.4 1.1 9.5 2.2 2.1 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 Ion_trans PF00520.26 ETO27212.1 - 7.2e-10 38.4 17.0 7.2e-10 38.4 11.8 1.9 2 0 0 2 2 2 1 Ion transport protein Zn_ribbon_recom PF13408.1 ETO27212.1 - 0.56 10.5 5.0 1.9 8.8 3.5 1.9 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain DUF2574 PF10836.3 ETO27213.1 - 0.02 14.6 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2574) FTHFS PF01268.14 ETO27213.1 - 0.085 10.8 0.0 0.12 10.3 0.0 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase SOBP PF15279.1 ETO27213.1 - 1.4 9.2 5.9 4.3 7.6 2.5 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein DUF1712 PF08217.6 ETO27214.1 - 3.3e-11 42.1 0.8 4.7e-11 41.6 0.0 1.6 1 1 1 2 2 2 1 Fungal domain of unknown function (DUF1712) DGF-1_C PF11040.3 ETO27215.1 - 0.077 12.8 2.7 9.2 6.2 0.0 2.7 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Mucin PF01456.12 ETO27215.1 - 0.17 11.6 19.6 0.34 10.6 13.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DASH_Dad3 PF08656.5 ETO27215.1 - 0.3 10.7 4.2 3.3 7.4 2.9 2.6 1 1 0 1 1 1 0 DASH complex subunit Dad3 Senescence_reg PF04520.8 ETO27215.1 - 5.1 7.5 8.8 0.27 11.7 1.8 1.9 2 0 0 2 2 2 0 Senescence regulator Trypan_PARP PF05887.6 ETO27217.1 - 0.0041 16.9 28.5 0.0089 15.8 19.7 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) MIP-T3 PF10243.4 ETO27217.1 - 0.01 14.3 17.9 0.016 13.6 12.4 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Daxx PF03344.10 ETO27217.1 - 0.018 13.5 34.1 0.0037 15.8 19.7 2.1 2 0 0 2 2 2 0 Daxx Family CPL PF08144.6 ETO27218.1 - 4.6e-10 39.5 0.5 4.4e-05 23.3 0.0 3.7 3 0 0 3 3 3 2 CPL (NUC119) domain Fzo_mitofusin PF04799.8 ETO27220.1 - 0.074 12.4 0.3 0.1 11.9 0.2 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF1510 PF07423.6 ETO27221.1 - 4.6e-06 26.1 14.8 4.6e-06 26.1 10.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) Neur_chan_memb PF02932.11 ETO27221.1 - 8.9e-05 22.4 1.6 8.9e-05 22.4 1.1 2.1 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Kei1 PF08552.6 ETO27221.1 - 0.0025 17.5 2.9 0.0025 17.5 2.0 2.7 2 1 0 2 2 2 1 Inositolphosphorylceramide synthase subunit Kei1 TRAP_alpha PF03896.11 ETO27221.1 - 0.0035 16.3 1.5 0.0064 15.5 1.0 1.5 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Ion_trans PF00520.26 ETO27221.1 - 0.0044 16.2 0.5 0.02 14.1 0.0 2.1 2 0 0 2 2 2 1 Ion transport protein IncA PF04156.9 ETO27221.1 - 0.0046 16.5 1.2 0.011 15.3 0.2 1.9 2 0 0 2 2 2 1 IncA protein Tetraspannin PF00335.15 ETO27221.1 - 0.0073 15.6 2.0 0.013 14.7 1.4 1.3 1 0 0 1 1 1 1 Tetraspanin family Ycf1 PF05758.7 ETO27221.1 - 0.027 12.2 22.1 0.0059 14.4 12.8 1.5 1 1 0 1 1 1 0 Ycf1 Mem_trans PF03547.13 ETO27221.1 - 0.03 12.6 7.0 0.013 13.7 3.4 1.5 1 1 0 1 1 1 0 Membrane transport protein Ctr PF04145.10 ETO27221.1 - 0.033 14.2 9.2 4.9 7.2 4.5 2.9 1 1 1 2 2 2 0 Ctr copper transporter family SID-1_RNA_chan PF13965.1 ETO27221.1 - 0.036 12.2 7.1 0.017 13.3 3.4 1.5 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 ATG22 PF11700.3 ETO27221.1 - 0.04 12.3 0.9 0.081 11.3 0.6 1.5 1 1 0 1 1 1 0 Vacuole effluxer Atg22 like Nucleoside_tran PF01733.13 ETO27221.1 - 0.15 11.1 9.3 9.2 5.3 6.4 2.4 1 1 0 1 1 1 0 Nucleoside transporter OPT PF03169.10 ETO27221.1 - 0.18 10.1 0.8 0.33 9.3 0.0 1.7 2 0 0 2 2 2 0 OPT oligopeptide transporter protein Zip PF02535.17 ETO27221.1 - 1.3 7.9 11.4 0.099 11.6 4.0 1.9 1 1 1 2 2 2 0 ZIP Zinc transporter Caldesmon PF02029.10 ETO27221.1 - 1.3 7.3 34.3 2.1 6.6 23.8 1.2 1 0 0 1 1 1 0 Caldesmon OAD_gamma PF04277.8 ETO27221.1 - 3.8 7.9 9.0 1e+03 0.1 6.3 2.9 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF3899 PF13038.1 ETO27221.1 - 4.1 7.6 16.0 0.38 10.9 0.2 3.3 2 1 1 3 3 2 0 Domain of unknown function (DUF3899) Pex16 PF08610.5 ETO27221.1 - 4.6 6.1 14.4 0.15 10.9 4.8 1.9 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) Apt1 PF10351.4 ETO27221.1 - 6 5.5 31.6 0.11 11.2 0.6 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Menin PF05053.8 ETO27221.1 - 6.8 4.7 14.5 0.21 9.6 5.4 1.7 2 0 0 2 2 2 0 Menin PH PF00169.24 ETO27223.1 - 1.5e-13 50.7 1.8 1.5e-13 50.7 1.3 1.9 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 ETO27223.1 - 2.9e-09 37.1 7.8 3.5e-08 33.6 3.0 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 ETO27223.1 - 3.3e-08 33.4 1.2 8.2e-08 32.2 0.8 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 ETO27223.1 - 1.2e-06 28.3 2.0 3e-06 27.0 1.4 1.6 1 0 0 1 1 1 1 PH domain PH_6 PF15406.1 ETO27223.1 - 0.00018 21.5 1.5 0.021 14.8 0.1 2.3 2 0 0 2 2 2 2 Pleckstrin homology domain PH_2 PF08458.5 ETO27223.1 - 0.025 14.4 0.7 0.054 13.4 0.5 1.6 1 0 0 1 1 1 0 Plant pleckstrin homology-like region Lipl32 PF12103.3 ETO27223.1 - 0.038 13.4 2.5 0.042 13.3 0.8 1.7 2 0 0 2 2 2 0 Surface lipoprotein of Spirochaetales order DUF1993 PF09351.5 ETO27223.1 - 0.043 13.7 0.2 0.074 12.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) Colicin_Pyocin PF01320.13 ETO27223.1 - 0.064 13.1 0.3 0.46 10.3 0.0 2.4 3 0 0 3 3 3 0 Colicin immunity protein / pyocin immunity protein F-box-like PF12937.2 ETO27224.1 - 0.0012 18.4 2.0 0.0024 17.5 1.4 1.5 1 0 0 1 1 1 1 F-box-like DUF267 PF03268.9 ETO27225.1 - 0.059 12.1 0.5 0.077 11.8 0.4 1.2 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF267 Ribosomal_S2 PF00318.15 ETO27225.1 - 0.095 11.9 1.8 0.13 11.4 1.2 1.3 1 0 0 1 1 1 0 Ribosomal protein S2 DUF2796 PF10986.3 ETO27226.1 - 0.00032 20.7 3.6 0.00097 19.1 2.5 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2796) DUF2457 PF10446.4 ETO27226.1 - 7.1 5.2 11.0 15 4.1 7.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Mem_trans PF03547.13 ETO27227.1 - 0.03 12.6 7.6 0.038 12.2 5.2 1.2 1 0 0 1 1 1 0 Membrane transport protein Otopetrin PF03189.8 ETO27227.1 - 0.032 13.2 4.6 0.046 12.7 3.2 1.3 1 0 0 1 1 1 0 Otopetrin SID-1_RNA_chan PF13965.1 ETO27227.1 - 0.21 9.7 5.9 0.24 9.5 4.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Polyoma_lg_T_C PF06431.6 ETO27227.1 - 0.95 8.0 5.7 0.18 10.3 1.4 1.6 1 1 1 2 2 2 0 Polyomavirus large T antigen C-terminus Neur_chan_memb PF02932.11 ETO27227.1 - 1.7 8.4 7.6 2.7 7.8 5.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MSC PF09402.5 ETO27229.1 - 1.8e-05 23.6 1.5 1.8e-05 23.6 1.1 3.0 2 1 1 3 3 3 2 Man1-Src1p-C-terminal domain DUF3619 PF12279.3 ETO27229.1 - 0.04 14.0 0.1 1.2 9.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3619) vMSA PF00695.14 ETO27229.1 - 0.041 13.0 1.6 0.51 9.4 0.6 2.3 2 0 0 2 2 2 0 Major surface antigen from hepadnavirus PepSY_TM_2 PF13703.1 ETO27229.1 - 0.27 11.4 2.5 11 6.2 0.2 2.7 2 1 0 2 2 2 0 PepSY-associated TM helix DUF4401 PF14351.1 ETO27229.1 - 1.9 7.4 7.5 0.1 11.6 1.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4401) RuBisCO_small PF00101.15 ETO27230.1 - 0.0083 15.9 0.1 1.1 9.0 0.0 2.9 3 0 0 3 3 3 2 Ribulose bisphosphate carboxylase, small chain VWA_3 PF13768.1 ETO27231.1 - 1.7e-16 60.2 0.0 2.6e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 ETO27231.1 - 2.1e-11 44.2 0.0 2.9e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 ETO27231.1 - 1.3e-07 31.5 0.0 1.8e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 ETO27231.1 - 8.8e-05 22.4 0.0 0.00021 21.2 0.0 1.5 1 1 0 1 1 1 1 vWA found in TerF C terminus VWA_CoxE PF05762.9 ETO27231.1 - 0.011 14.9 0.0 0.014 14.5 0.0 1.1 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Copine PF07002.11 ETO27231.1 - 0.043 13.5 0.0 0.054 13.2 0.0 1.2 1 0 0 1 1 1 0 Copine zf-TRAF PF02176.13 ETO27232.1 - 1e-05 25.8 3.5 1e-05 25.8 2.4 3.0 2 1 1 3 3 3 1 TRAF-type zinc finger WD40 PF00400.27 ETO27233.1 - 4e-89 289.6 15.8 1.7e-13 49.8 0.1 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat Kelch_1 PF01344.20 ETO27233.1 - 1.2e-06 27.9 11.2 0.00026 20.4 0.9 3.2 2 0 0 2 2 2 2 Kelch motif Cytochrom_D1 PF02239.11 ETO27233.1 - 7.4e-06 24.5 1.7 0.0028 16.0 0.1 3.2 2 1 3 5 5 5 3 Cytochrome D1 heme domain Kelch_3 PF13415.1 ETO27233.1 - 1.6e-05 24.8 0.1 8.8e-05 22.5 0.0 2.4 2 0 0 2 2 1 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO27233.1 - 1.7e-05 24.8 14.9 0.014 15.5 0.4 5.4 6 1 1 7 7 5 2 Kelch motif Kelch_5 PF13854.1 ETO27233.1 - 3.7e-05 23.5 7.1 0.0014 18.5 0.5 3.8 3 0 0 3 3 3 2 Kelch motif PQQ_2 PF13360.1 ETO27233.1 - 3.9e-05 23.2 1.6 0.001 18.5 1.1 2.4 1 1 0 1 1 1 1 PQQ-like domain Kelch_4 PF13418.1 ETO27233.1 - 0.00034 20.3 3.1 0.066 12.9 0.2 4.2 3 0 0 3 3 3 1 Galactose oxidase, central domain Gmad1 PF10647.4 ETO27233.1 - 0.0012 18.3 0.1 0.52 9.6 0.1 3.0 1 1 1 2 2 2 1 Lipoprotein LpqB beta-propeller domain DUF1258 PF06869.7 ETO27233.1 - 0.0051 15.9 0.5 2.6 7.0 0.0 3.4 3 1 1 4 4 4 2 Protein of unknown function (DUF1258) PD40 PF07676.7 ETO27233.1 - 0.038 13.6 11.1 13 5.5 0.0 5.8 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat PLD_C PF12357.3 ETO27233.1 - 0.041 13.3 0.0 22 4.6 0.0 3.7 4 0 0 4 4 4 0 Phospholipase D C terminal Proteasome_A_N PF10584.4 ETO27233.1 - 0.081 12.2 2.0 41 3.6 0.0 4.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Kelch_2 PF07646.10 ETO27233.1 - 0.12 12.2 6.9 1.8 8.4 0.2 3.9 4 0 0 4 4 4 0 Kelch motif Glyco_hydro_31 PF01055.21 ETO27234.1 - 5.3e-24 84.8 0.1 7.5e-24 84.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Ion_trans_2 PF07885.11 ETO27236.1 - 3.2e-11 42.7 12.7 4e-06 26.4 3.8 2.4 2 0 0 2 2 2 2 Ion channel EF-hand_1 PF00036.27 ETO27236.1 - 1.3e-08 33.5 7.7 3.9e-05 22.6 0.4 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 ETO27236.1 - 2.3e-08 34.0 8.0 1.1e-05 25.4 2.0 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO27236.1 - 1.9e-07 30.3 2.7 0.0013 18.4 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 ETO27236.1 - 2e-05 23.7 6.7 0.0024 17.1 0.4 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 ETO27236.1 - 9.6e-05 21.9 4.4 0.051 13.2 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain pair IRK PF01007.15 ETO27236.1 - 0.045 12.5 1.2 0.17 10.6 0.2 2.0 2 0 0 2 2 2 0 Inward rectifier potassium channel UPF0542 PF15086.1 ETO27237.1 - 0.069 12.8 0.4 0.59 9.8 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 SPX PF03105.14 ETO27238.1 - 1.3e-08 34.9 5.9 2.1e-08 34.3 4.1 1.3 1 0 0 1 1 1 1 SPX domain Clat_adaptor_s PF01217.15 ETO27239.1 - 0.027 14.1 0.0 0.056 13.1 0.0 1.5 1 0 0 1 1 1 0 Clathrin adaptor complex small chain RibD_C PF01872.12 ETO27239.1 - 0.12 11.9 0.6 0.16 11.5 0.4 1.2 1 0 0 1 1 1 0 RibD C-terminal domain GvpK PF05121.7 ETO27239.1 - 0.17 11.7 2.3 0.17 11.7 0.3 1.8 2 0 0 2 2 2 0 Gas vesicle protein K EMP24_GP25L PF01105.19 ETO27239.1 - 0.29 10.8 6.6 0.36 10.5 4.6 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD XhlA PF10779.4 ETO27239.1 - 0.5 10.3 8.8 0.15 11.9 4.0 1.8 2 0 0 2 2 2 0 Haemolysin XhlA DUF406 PF04175.7 ETO27239.1 - 0.71 10.3 5.7 0.28 11.6 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF406) FlxA PF14282.1 ETO27239.1 - 2 8.4 10.8 0.28 11.1 2.7 2.2 1 1 0 2 2 2 0 FlxA-like protein LMBR1 PF04791.11 ETO27239.1 - 5.5 5.4 5.2 6.1 5.3 3.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Suc_Fer-like PF06999.7 ETO27240.1 - 0.025 14.6 3.8 0.038 13.9 2.6 1.3 1 1 0 1 1 1 0 Sucrase/ferredoxin-like Cyc-maltodext_C PF10438.4 ETO27240.1 - 0.84 9.7 6.5 3.4 7.7 1.2 2.5 2 0 0 2 2 2 0 Cyclo-malto-dextrinase C-terminal domain RVT_1 PF00078.22 ETO27241.1 - 1.9e-11 43.7 0.2 4.7e-11 42.4 0.1 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RasGEF_N PF00618.15 ETO27241.1 - 0.077 13.1 0.3 0.18 11.8 0.2 1.7 1 0 0 1 1 1 0 RasGEF N-terminal motif MCP_N PF05581.7 ETO27243.1 - 8.2 6.6 10.1 9.9 6.3 0.5 3.7 3 1 0 3 3 3 0 Vibrio chemotaxis protein N terminus RhoGAP PF00620.22 ETO27244.1 - 1.8e-20 73.1 0.0 4e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain Alpha-2-MRAP_C PF06401.6 ETO27245.1 - 0.033 14.0 7.6 0.044 13.6 5.3 1.1 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain NPR3 PF03666.8 ETO27245.1 - 6.6 5.1 9.3 3.1 6.2 5.1 1.3 1 1 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pal1 PF08316.6 ETO27245.1 - 8 6.9 7.8 7.5 7.0 2.6 2.1 2 0 0 2 2 2 0 Pal1 cell morphology protein FYRN PF05964.9 ETO27246.1 - 1.6e-10 40.2 0.1 2.9e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.9 ETO27246.1 - 2.6e-05 23.9 0.0 5.9e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 F/Y rich C-terminus PH PF00169.24 ETO27248.1 - 1.3e-08 34.9 0.1 2.3e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 PH domain Mcp5_PH PF12814.2 ETO27248.1 - 0.077 12.9 2.0 0.15 11.9 0.2 2.0 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology ThiF PF00899.16 ETO27249.1 - 6.5e-06 26.0 3.1 0.013 15.3 0.0 2.5 2 0 0 2 2 2 2 ThiF family Pex14_N PF04695.8 ETO27249.1 - 0.03 14.3 2.6 3.8 7.5 0.4 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Toprim PF01751.17 ETO27249.1 - 0.068 13.1 3.7 1.8 8.5 0.2 2.8 3 0 0 3 3 3 0 Toprim domain DUF912 PF06024.7 ETO27249.1 - 2 8.5 13.9 15 5.7 4.5 3.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) WD40 PF00400.27 ETO27250.1 - 3.3e-58 191.6 22.8 1.1e-11 44.1 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO27250.1 - 1.7e-08 33.0 6.5 0.0036 15.5 0.4 5.1 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO27250.1 - 4.3e-07 28.5 0.1 0.0097 14.2 0.0 2.3 1 1 1 2 2 2 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO27250.1 - 5.5e-06 26.0 0.2 0.00025 20.5 0.0 2.5 1 1 1 2 2 2 2 PQQ-like domain Me-amine-dh_H PF06433.6 ETO27250.1 - 0.019 13.6 0.2 1 7.8 0.0 2.8 2 1 2 4 4 4 0 Methylamine dehydrogenase heavy chain (MADH) FAM219A PF15260.1 ETO27250.1 - 0.041 14.2 0.9 0.51 10.6 0.1 2.4 2 0 0 2 2 2 0 Protein family FAM219A Proteasome_A_N PF10584.4 ETO27250.1 - 0.13 11.6 0.3 68 2.9 0.0 3.7 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature PD40 PF07676.7 ETO27250.1 - 0.17 11.6 3.4 71 3.2 0.0 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 ETO27251.1 - 1.4e-70 230.8 23.3 4.6e-13 48.5 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO27251.1 - 2.7e-11 43.5 1.1 0.0061 16.2 0.0 3.9 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO27251.1 - 9.4e-09 34.0 0.1 0.0058 14.9 0.0 3.4 1 1 3 4 4 4 2 Cytochrome D1 heme domain Nup160 PF11715.3 ETO27251.1 - 6.5e-07 27.8 11.3 0.095 10.8 0.1 5.1 1 1 3 4 4 4 4 Nucleoporin Nup120/160 PD40 PF07676.7 ETO27251.1 - 1.6e-05 24.4 4.6 3.1 7.5 0.0 5.1 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO27251.1 - 2.3e-05 23.9 1.8 0.0054 16.2 0.0 2.9 1 1 0 2 2 2 1 PQQ-like domain Resistin PF06954.6 ETO27251.1 - 7.1e-05 23.0 0.8 18 5.6 0.0 4.5 3 1 1 4 4 4 0 Resistin DPPIV_N PF00930.16 ETO27251.1 - 0.00012 20.7 0.0 0.44 9.0 0.0 3.1 1 1 0 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF1258 PF06869.7 ETO27251.1 - 0.00062 18.9 4.1 0.058 12.4 0.1 3.9 3 1 2 5 5 5 1 Protein of unknown function (DUF1258) Coatomer_WDAD PF04053.9 ETO27251.1 - 0.008 15.0 1.2 1.7 7.3 0.2 2.6 1 1 1 3 3 3 2 Coatomer WD associated region Proteasome_A_N PF10584.4 ETO27251.1 - 0.1 11.9 4.8 27 4.1 0.4 3.8 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Ricin_B_lectin PF00652.17 ETO27251.1 - 0.16 12.0 5.2 8.8 6.3 0.2 3.6 1 1 2 3 3 3 0 Ricin-type beta-trefoil lectin domain BBS2_Mid PF14783.1 ETO27251.1 - 0.46 10.2 9.8 13 5.6 0.1 5.5 2 2 3 5 5 5 0 Ciliary BBSome complex subunit 2, middle region G8 PF10162.4 ETO27253.1 - 3.3e-23 81.8 0.1 6.9e-23 80.7 0.1 1.5 1 0 0 1 1 1 1 G8 domain Kelch_6 PF13964.1 ETO27254.1 - 1.4e-07 31.4 1.4 0.0019 18.2 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 ETO27254.1 - 3.8e-05 23.2 2.7 0.077 12.8 0.1 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO27254.1 - 0.00025 20.5 4.4 0.035 13.6 0.1 3.3 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO27254.1 - 0.0087 15.8 0.8 0.026 14.3 0.1 2.3 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO27254.1 - 0.036 14.0 3.0 2.8 8.0 0.3 3.8 4 0 0 4 4 4 0 Kelch motif EF-hand_7 PF13499.1 ETO27255.1 - 6.7e-08 32.5 0.3 1.9e-07 31.0 0.1 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO27255.1 - 3.7e-05 23.2 0.5 0.32 10.9 0.0 3.8 4 0 0 4 4 4 2 EF-hand domain RST PF12174.3 ETO27255.1 - 0.0016 18.1 0.0 0.0065 16.2 0.0 2.1 1 1 1 2 2 2 1 RCD1-SRO-TAF4 (RST) plant domain EF-hand_1 PF00036.27 ETO27255.1 - 0.0038 16.4 1.8 0.12 11.7 0.1 3.4 4 0 0 4 4 4 1 EF hand EF-hand_5 PF13202.1 ETO27255.1 - 0.076 12.3 0.1 0.55 9.6 0.0 2.3 2 0 0 2 2 2 0 EF hand SPARC_Ca_bdg PF10591.4 ETO27255.1 - 0.084 12.9 0.3 0.33 10.9 0.0 2.0 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Lipoprotein_1 PF00820.14 ETO27256.1 - 0.039 13.0 0.7 0.056 12.5 0.5 1.2 1 0 0 1 1 1 0 Borrelia lipoprotein Sporozoite_P67 PF05642.6 ETO27256.1 - 2.9 5.6 8.2 3.6 5.3 5.7 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pkinase PF00069.20 ETO27257.1 - 1.1e-31 109.9 0.0 1.3e-29 103.1 0.0 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO27257.1 - 5.1e-17 61.8 0.0 1.5e-08 34.0 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Seadorna_VP7 PF07387.6 ETO27257.1 - 0.016 14.0 0.0 0.098 11.4 0.0 2.1 2 0 0 2 2 2 0 Seadornavirus VP7 Kinase-like PF14531.1 ETO27257.1 - 0.05 12.5 0.0 0.084 11.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Ion_trans PF00520.26 ETO27258.1 - 4.2e-19 68.6 64.4 2.8e-18 65.9 17.5 3.2 3 1 0 3 3 3 2 Ion transport protein EF-hand_6 PF13405.1 ETO27258.1 - 0.00089 18.9 2.5 0.62 10.0 0.6 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 ETO27258.1 - 0.0018 18.3 0.3 1 9.5 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 ETO27258.1 - 0.004 16.3 2.9 0.41 10.0 0.6 3.0 2 0 0 2 2 2 2 EF hand PH PF00169.24 ETO27259.1 - 6.7e-06 26.2 2.1 6.7e-06 26.2 1.4 2.2 2 1 0 2 2 2 1 PH domain PH_8 PF15409.1 ETO27259.1 - 0.022 14.8 0.2 0.069 13.2 0.1 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain AAA_22 PF13401.1 ETO27259.1 - 0.082 13.0 0.1 0.32 11.1 0.1 2.1 1 0 0 1 1 1 0 AAA domain Actin PF00022.14 ETO27260.1 - 1.6e-111 372.5 0.0 1.9e-111 372.3 0.0 1.0 1 0 0 1 1 1 1 Actin RNA_pol_Rpb1_5 PF04998.12 ETO27260.1 - 0.11 11.7 0.1 0.17 11.0 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 RasGAP_C PF03836.10 ETO27261.1 - 0.066 12.9 3.2 0.094 12.4 2.2 1.3 1 0 0 1 1 1 0 RasGAP C-terminus RNA_pol_3_Rpc31 PF11705.3 ETO27261.1 - 0.11 12.4 7.7 0.12 12.2 5.3 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2796 PF10986.3 ETO27261.1 - 0.34 10.8 2.6 0.4 10.6 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) TFIIF_alpha PF05793.7 ETO27261.1 - 0.37 9.0 7.5 0.42 8.9 5.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Med19 PF10278.4 ETO27261.1 - 0.47 10.0 5.6 0.55 9.8 3.9 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Pkinase PF00069.20 ETO27262.1 - 4.5e-40 137.4 4.9 4.9e-16 58.6 0.0 3.9 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 ETO27262.1 - 6.5e-21 74.5 3.2 6.1e-12 45.1 0.5 4.0 3 1 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.9 ETO27262.1 - 0.0016 17.5 0.3 0.0028 16.7 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 ETO27262.1 - 0.0022 17.3 3.0 0.0051 16.1 0.1 2.5 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kinase-like PF14531.1 ETO27262.1 - 0.004 16.1 0.0 0.28 10.1 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 ETO27262.1 - 0.014 15.0 0.1 0.029 14.1 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family TMCO5 PF14992.1 ETO27263.1 - 0.0016 17.6 17.1 0.0016 17.6 11.8 2.1 2 0 0 2 2 2 1 TMCO5 family Myosin_tail_1 PF01576.14 ETO27263.1 - 0.0093 13.7 30.5 0.012 13.3 21.2 1.1 1 0 0 1 1 1 1 Myosin tail DUF1664 PF07889.7 ETO27263.1 - 0.027 14.2 20.1 0.16 11.8 2.5 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Mu-like_Pro PF10123.4 ETO27263.1 - 0.034 13.5 7.1 0.046 13.1 4.9 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein DUF4201 PF13870.1 ETO27263.1 - 0.15 11.5 32.1 0.034 13.5 9.9 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) Spc7 PF08317.6 ETO27263.1 - 0.19 10.3 32.9 0.46 9.0 6.4 3.0 1 1 1 3 3 3 0 Spc7 kinetochore protein FUSC PF04632.7 ETO27263.1 - 0.23 9.8 3.7 0.29 9.5 2.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3858 PF12970.2 ETO27263.1 - 0.27 11.0 3.0 0.17 11.6 0.4 2.0 3 0 0 3 3 2 0 Domain of Unknown Function with PDB structure (DUF3858) DUF4559 PF15112.1 ETO27263.1 - 0.29 10.2 15.2 0.27 10.3 10.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) Baculo_PEP_C PF04513.7 ETO27263.1 - 0.49 10.2 10.6 23 4.8 5.7 3.0 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Rootletin PF15035.1 ETO27263.1 - 0.6 10.0 32.1 0.33 10.9 8.0 3.0 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Phage_Gp23 PF10669.4 ETO27263.1 - 0.62 10.1 10.4 0.095 12.8 3.0 2.3 1 1 1 2 2 2 0 Protein gp23 (Bacteriophage A118) DUF3584 PF12128.3 ETO27263.1 - 0.63 7.3 27.0 0.1 9.9 13.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) IFT57 PF10498.4 ETO27263.1 - 0.66 8.6 27.7 1.9 7.1 9.4 2.3 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 CDC37_N PF03234.9 ETO27263.1 - 1 9.6 24.2 1.5 9.1 12.5 2.1 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding DUF342 PF03961.8 ETO27263.1 - 1.1 7.5 24.2 0.22 9.8 9.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF342) Tropomyosin_1 PF12718.2 ETO27263.1 - 1.4 8.7 34.8 2.4 8.0 0.7 2.8 2 1 0 2 2 2 0 Tropomyosin like Laminin_II PF06009.7 ETO27263.1 - 1.4 8.6 22.8 6.3 6.5 2.3 3.2 1 1 2 3 3 3 0 Laminin Domain II ATG16 PF08614.6 ETO27263.1 - 1.8 8.3 31.4 0.3 10.8 6.8 3.1 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) COG2 PF06148.6 ETO27263.1 - 4.6 7.1 20.7 1.8 8.4 1.0 3.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ING PF12998.2 ETO27263.1 - 4.9 7.4 23.6 0.55 10.5 9.8 2.3 1 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF651 PF04895.7 ETO27263.1 - 5.7 6.6 11.7 3.8 7.1 0.9 3.2 3 0 0 3 3 3 0 Archaeal protein of unknown function (DUF651) Tropomyosin PF00261.15 ETO27263.1 - 6.1 5.8 32.7 5.9 5.9 1.2 2.2 1 1 1 2 2 2 0 Tropomyosin Jnk-SapK_ap_N PF09744.4 ETO27263.1 - 7.1 6.6 31.2 0.039 13.9 3.8 3.1 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 DUF948 PF06103.6 ETO27263.1 - 7.2 6.5 15.8 1.4 8.8 1.2 3.3 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) RRF PF01765.14 ETO27263.1 - 8.1 5.8 18.4 0.15 11.5 6.6 2.4 2 1 1 3 3 3 0 Ribosome recycling factor Bacillus_HBL PF05791.6 ETO27263.1 - 9.1 5.6 22.3 16 4.8 7.8 2.8 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Ribonuc_2-5A PF06479.7 ETO27263.1 - 9.3 6.1 13.5 7.6 6.4 7.4 2.2 2 1 0 2 2 2 0 Ribonuclease 2-5A PEP-utilisers_N PF05524.8 ETO27263.1 - 9.9 5.9 11.3 29 4.4 2.2 3.2 1 1 2 3 3 3 0 PEP-utilising enzyme, N-terminal 2OG-FeII_Oxy_3 PF13640.1 ETO27264.1 - 6.2e-09 36.2 0.0 1.2e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.1 ETO27264.1 - 0.00098 19.3 0.0 0.0038 17.4 0.0 2.0 1 1 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Oxygenase-NA PF09859.4 ETO27264.1 - 0.0011 18.3 0.1 0.015 14.5 0.0 2.3 2 1 0 2 2 2 1 Oxygenase, catalysing oxidative methylation of damaged DNA DUF2237 PF09996.4 ETO27264.1 - 0.038 13.4 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2237) Cupin_2 PF07883.6 ETO27264.1 - 0.068 12.6 0.0 0.16 11.4 0.0 1.7 1 1 0 1 1 1 0 Cupin domain Mito_carr PF00153.22 ETO27266.1 - 2.1e-18 65.7 1.0 1.1e-14 53.9 0.0 3.1 2 1 0 2 2 2 2 Mitochondrial carrier protein AF-4 PF05110.8 ETO27266.1 - 0.018 12.9 4.2 0.026 12.4 2.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF4179 PF13786.1 ETO27266.1 - 0.034 14.3 1.8 0.11 12.7 1.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Herpes_US9 PF06072.6 ETO27266.1 - 0.14 12.0 2.6 2 8.3 0.1 2.7 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 RAMP4 PF06624.7 ETO27266.1 - 0.15 11.6 1.6 0.24 10.9 0.2 2.0 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 LMBR1 PF04791.11 ETO27266.1 - 0.33 9.4 5.1 0.24 9.9 2.1 1.7 2 0 0 2 2 2 0 LMBR1-like membrane protein Kinase-like PF14531.1 ETO27268.1 - 0.053 12.4 0.4 0.08 11.8 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Pkinase PF00069.20 ETO27268.1 - 0.2 10.7 3.3 0.35 9.9 2.3 1.7 1 1 0 1 1 1 0 Protein kinase domain DUF2777 PF10949.3 ETO27268.1 - 2.9 7.5 9.1 0.57 9.8 3.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2777) WD40 PF00400.27 ETO27269.1 - 1.3e-29 100.9 9.4 4.5e-11 42.2 0.6 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 ETO27269.1 - 4.8e-08 32.9 0.2 0.00014 21.6 0.0 2.5 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 ETO27269.1 - 0.00019 20.3 1.9 0.0035 16.2 0.1 2.5 1 1 1 2 2 2 1 Coatomer WD associated region Cytochrom_D1 PF02239.11 ETO27269.1 - 0.0013 17.0 0.2 0.0047 15.2 0.0 1.9 1 1 1 2 2 2 1 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO27269.1 - 0.0022 17.1 0.5 0.13 11.3 0.0 2.3 1 1 1 2 2 2 1 Neuroblastoma-amplified sequence, N terminal NHL PF01436.16 ETO27269.1 - 0.0026 17.6 0.0 27 4.9 0.0 3.8 3 0 0 3 3 3 0 NHL repeat DUF1513 PF07433.6 ETO27269.1 - 0.007 15.3 0.1 2.2 7.1 0.0 2.7 1 1 0 2 2 2 2 Protein of unknown function (DUF1513) PQQ_2 PF13360.1 ETO27269.1 - 0.0075 15.7 0.1 2.8 7.3 0.0 2.2 1 1 1 2 2 2 2 PQQ-like domain Nup160 PF11715.3 ETO27269.1 - 0.022 12.9 3.7 0.14 10.2 2.0 2.2 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Lactonase PF10282.4 ETO27269.1 - 0.046 12.7 0.2 0.17 10.9 0.0 2.0 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller Methyltransf_3 PF01596.12 ETO27269.1 - 0.079 12.0 0.0 9.1 5.2 0.0 2.2 1 1 1 2 2 2 0 O-methyltransferase TFIIIC_delta PF12657.2 ETO27269.1 - 0.08 12.6 0.9 1.3 8.7 0.1 2.6 2 1 1 3 3 3 0 Transcription factor IIIC subunit delta N-term Proteasome_A_N PF10584.4 ETO27269.1 - 0.29 10.4 2.8 3.8 6.9 0.0 3.2 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature PD40 PF07676.7 ETO27269.1 - 3.2 7.5 5.6 49 3.7 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat TPR_12 PF13424.1 ETO27270.1 - 3.1e-32 110.3 0.7 7.5e-11 41.8 0.0 2.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO27270.1 - 3.2e-16 58.7 0.3 1.1e-08 34.6 0.2 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 ETO27270.1 - 4.1e-09 35.6 1.6 0.0047 16.7 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO27270.1 - 2.9e-08 32.9 0.6 0.00041 19.9 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO27270.1 - 7e-08 31.7 5.1 0.00025 20.5 0.3 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO27270.1 - 9.4e-07 28.5 0.0 8.2e-05 22.4 0.0 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO27270.1 - 5.4e-06 25.8 3.8 0.0022 17.6 0.1 4.4 4 1 1 5 5 5 1 Tetratricopeptide repeat SecD-TM1 PF13721.1 ETO27270.1 - 0.014 15.6 5.1 0.021 15.0 1.5 2.4 2 0 0 2 2 2 0 SecD export protein N-terminal TM region wnt PF00110.14 ETO27270.1 - 0.018 14.2 0.4 0.03 13.5 0.3 1.3 1 0 0 1 1 1 0 wnt family TPR_17 PF13431.1 ETO27270.1 - 0.038 14.1 0.1 0.41 10.9 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO27270.1 - 0.099 13.1 0.1 12 6.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF87 PF01935.12 ETO27271.1 - 0.84 9.4 7.1 1.1 9.0 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 Carboxyl_trans PF01039.17 ETO27271.1 - 0.89 7.8 3.6 1 7.6 2.5 1.2 1 0 0 1 1 1 0 Carboxyl transferase domain DUF3492 PF11997.3 ETO27271.1 - 2.8 7.3 5.9 3.4 7.1 3.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3492) ALMT PF11744.3 ETO27271.1 - 3.5 6.1 8.0 4.3 5.8 5.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter YqzE PF14038.1 ETO27271.1 - 5 6.9 17.0 3 7.6 7.7 2.6 2 0 0 2 2 2 0 YqzE-like protein Kinesin PF00225.18 ETO27272.1 - 9.1e-13 47.6 0.0 1.1e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Herpes_V23 PF01802.12 ETO27272.1 - 0.15 11.0 0.1 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein Kinesin PF00225.18 ETO27273.1 - 6.1e-09 35.0 0.0 4.8e-08 32.0 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain DMAP_binding PF06464.6 ETO27274.1 - 0.0064 17.0 3.5 0.084 13.4 0.2 3.0 2 0 0 2 2 2 1 DMAP1-binding Domain VWD PF00094.20 ETO27274.1 - 0.089 12.9 0.3 0.089 12.9 0.2 2.5 2 1 1 3 3 3 0 von Willebrand factor type D domain Metal_resist PF13801.1 ETO27274.1 - 3.9 7.4 6.6 5.2 7.0 0.1 3.5 4 0 0 4 4 4 0 Heavy-metal resistance Mic1 PF07035.7 ETO27275.1 - 0.00047 19.5 0.1 0.0013 18.1 0.1 1.8 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like Fimbrial PF00419.15 ETO27275.1 - 0.033 14.3 0.7 0.9 9.7 0.0 2.3 2 0 0 2 2 2 0 Fimbrial protein Bcr-Abl_Oligo PF09036.5 ETO27275.1 - 0.056 13.3 0.1 0.51 10.3 0.0 2.2 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DUF2946 PF11162.3 ETO27275.1 - 0.16 12.1 1.0 4.7 7.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) Exostosin PF03016.10 ETO27278.1 - 1.9e-05 23.8 0.9 0.00011 21.3 0.1 1.9 2 0 0 2 2 2 1 Exostosin family PDDEXK_3 PF13366.1 ETO27278.1 - 0.0072 16.3 0.1 0.031 14.3 0.0 1.9 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily Taxilin PF09728.4 ETO27279.1 - 2.7e-05 23.4 6.5 3.4e-05 23.0 4.5 1.2 1 0 0 1 1 1 1 Myosin-like coiled-coil protein V_ATPase_I PF01496.14 ETO27279.1 - 0.003 15.5 5.9 0.0038 15.1 4.1 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF507 PF04368.8 ETO27279.1 - 0.035 13.7 4.4 0.052 13.1 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF507) TINF2_N PF14973.1 ETO27279.1 - 0.084 13.0 2.5 0.15 12.1 1.8 1.4 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus Muted PF14942.1 ETO27279.1 - 0.65 9.8 9.7 0.97 9.2 6.4 1.5 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein Tup_N PF08581.5 ETO27279.1 - 0.95 9.6 7.7 0.28 11.3 1.7 2.5 1 1 1 2 2 2 0 Tup N-terminal TB2_DP1_HVA22 PF03134.14 ETO27280.1 - 1.5e-10 40.6 6.4 1.5e-10 40.6 4.4 2.2 1 1 1 2 2 2 1 TB2/DP1, HVA22 family EAL PF00563.15 ETO27281.1 - 9.6e-40 136.5 0.2 1.6e-20 73.6 0.0 2.0 1 1 1 2 2 2 2 EAL domain DUF605 PF04652.11 ETO27282.1 - 0.025 13.9 18.7 0.03 13.7 12.9 1.2 1 0 0 1 1 1 0 Vta1 like DUF667 PF05018.8 ETO27282.1 - 0.19 10.9 3.1 0.3 10.3 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF667) Nop14 PF04147.7 ETO27282.1 - 0.48 8.2 26.7 0.59 7.9 18.5 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 ETO27282.1 - 1 7.7 28.3 1.3 7.3 19.6 1.1 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 ETO27282.1 - 2.5 7.2 27.3 3.6 6.7 18.9 1.3 1 0 0 1 1 1 0 SDA1 Sporozoite_P67 PF05642.6 ETO27282.1 - 3 5.6 13.2 4.4 5.0 9.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TFIIF_alpha PF05793.7 ETO27282.1 - 4.3 5.5 26.3 5.9 5.1 18.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2890 PF11081.3 ETO27282.1 - 5.2 7.0 17.2 7.2 6.6 11.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Merozoite_SPAM PF07133.6 ETO27282.1 - 7.3 6.4 38.3 12 5.7 26.5 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF1510 PF07423.6 ETO27282.1 - 7.5 5.8 22.9 12 5.2 15.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2457 PF10446.4 ETO27282.1 - 8.2 5.0 24.5 11 4.5 16.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RRN3 PF05327.6 ETO27282.1 - 9.5 4.1 18.1 14 3.6 12.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Viral_cys_rich PF08008.7 ETO27283.1 - 0.033 13.7 0.0 0.072 12.6 0.0 1.6 1 0 0 1 1 1 0 Viral cysteine rich Pkinase PF00069.20 ETO27283.1 - 0.043 12.9 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain zf-DHHC PF01529.15 ETO27284.1 - 1.3e-29 102.7 19.5 1.3e-29 102.7 13.5 2.7 1 1 1 3 3 3 1 DHHC palmitoyltransferase TPT PF03151.11 ETO27284.1 - 0.0026 17.4 0.7 0.0026 17.4 0.5 1.8 2 0 0 2 2 2 1 Triose-phosphate Transporter family Mob_synth_C PF06463.8 ETO27284.1 - 0.033 13.8 0.6 0.077 12.6 0.4 1.7 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C CCSMST1 PF15013.1 ETO27284.1 - 0.14 12.0 1.0 15 5.5 0.2 2.6 2 0 0 2 2 2 0 CCSMST1 family RGS-like PF09128.6 ETO27285.1 - 0.48 9.8 3.5 1 8.8 2.4 1.5 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain DUF3439 PF11921.3 ETO27285.1 - 0.62 9.8 7.0 1.3 8.8 4.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Pkinase PF00069.20 ETO27286.1 - 3e-18 65.9 0.0 3.6e-18 65.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO27286.1 - 2.6e-05 23.4 0.0 2.9e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 ETO27287.1 - 2e-26 92.6 0.2 2.2e-26 92.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO27287.1 - 3.1e-16 59.2 0.0 3.3e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETO27287.1 - 0.00071 19.3 0.3 0.0012 18.6 0.2 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 ETO27287.1 - 0.00076 18.5 0.0 0.0008 18.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 ETO27287.1 - 0.0012 18.2 0.0 0.002 17.5 0.0 1.3 1 1 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 ETO27287.1 - 0.058 12.3 0.0 0.076 11.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Lipase_3 PF01764.20 ETO27288.1 - 1.7e-23 82.8 0.0 2.5e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 ETO27288.1 - 4.6e-05 22.8 0.0 8.3e-05 22.0 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 ETO27288.1 - 0.0019 17.9 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETO27288.1 - 0.0054 16.6 0.0 0.0058 16.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Glyco_hydro_2 PF00703.16 ETO27289.1 - 0.075 13.4 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 2 SAM_1 PF00536.25 ETO27290.1 - 7.1e-09 35.7 0.3 7.1e-09 35.7 0.2 2.1 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO27290.1 - 8.7e-08 31.9 0.3 8.7e-08 31.9 0.2 2.5 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) DUF3450 PF11932.3 ETO27290.1 - 0.014 14.6 21.2 0.032 13.5 14.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Laminin_II PF06009.7 ETO27290.1 - 0.12 12.1 9.7 0.29 10.8 6.7 1.7 1 0 0 1 1 1 0 Laminin Domain II DUF4482 PF14818.1 ETO27290.1 - 0.32 11.6 29.3 0.37 11.4 18.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4482) DUF4407 PF14362.1 ETO27290.1 - 2.8 6.8 17.3 4.3 6.2 12.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) VSG_B PF13206.1 ETO27290.1 - 4.8 6.2 16.2 11 5.0 11.2 1.5 1 0 0 1 1 1 0 Trypanosomal VSG domain Neur_chan_memb PF02932.11 ETO27290.1 - 5.5 6.7 11.1 0.74 9.6 4.6 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region VIT1 PF01988.14 ETO27291.1 - 0.018 14.5 0.4 0.039 13.4 0.3 1.6 1 0 0 1 1 1 0 VIT family COG2 PF06148.6 ETO27291.1 - 0.021 14.7 4.6 0.059 13.2 3.2 1.8 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1049 PF06305.6 ETO27291.1 - 0.063 12.7 0.0 0.37 10.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DDRGK PF09756.4 ETO27291.1 - 7.2 5.9 28.6 0.87 8.9 5.0 2.3 2 0 0 2 2 2 0 DDRGK domain Prothymosin PF03247.9 ETO27291.1 - 7.5 6.7 34.2 0.13 12.4 13.4 3.2 3 0 0 3 3 3 0 Prothymosin/parathymosin family PUB PF09409.5 ETO27292.1 - 6.9e-09 35.3 0.7 1.9e-08 33.9 0.2 2.1 2 0 0 2 2 2 1 PUB domain DUF2357 PF09823.4 ETO27292.1 - 0.088 11.8 3.8 0.17 10.9 0.4 2.5 2 2 0 2 2 2 0 Domain of unknown function (DUF2357) MecA_N PF05223.6 ETO27292.1 - 2.7 8.1 5.4 0.5 10.4 0.6 2.1 3 0 0 3 3 3 0 NTF2-like N-terminal transpeptidase domain DUF2777 PF10949.3 ETO27293.1 - 0.081 12.5 1.0 0.15 11.7 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2777) GHMP_kinases_N PF00288.21 ETO27294.1 - 2.2e-07 30.8 1.8 3.7e-07 30.0 1.2 1.4 1 0 0 1 1 1 1 GHMP kinases N terminal domain Kelch_6 PF13964.1 ETO27297.1 - 0.0033 17.5 0.2 0.0086 16.2 0.1 1.7 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETO27298.1 - 1.1e-08 34.8 0.9 0.00012 22.0 0.1 3.3 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO27298.1 - 4.4e-05 22.9 0.2 0.00013 21.3 0.1 1.8 1 0 0 1 1 1 1 Kelch motif Kelch_4 PF13418.1 ETO27298.1 - 4.6e-05 23.1 0.0 0.0013 18.4 0.0 2.5 2 1 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO27298.1 - 7.3e-05 22.6 0.4 0.00017 21.4 0.1 1.8 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO27298.1 - 0.0098 16.0 0.0 0.046 13.8 0.0 2.1 3 0 0 3 3 3 1 Galactose oxidase, central domain WD40 PF00400.27 ETO27299.1 - 1e-52 174.1 9.6 2.6e-11 42.9 0.3 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 ETO27299.1 - 3.4e-06 26.9 0.1 2.7e-05 23.9 0.0 2.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO27299.1 - 0.00011 20.4 2.5 0.1 10.6 0.1 2.8 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO27299.1 - 0.0059 15.3 4.5 0.34 9.5 0.2 3.4 1 1 1 2 2 2 2 Nup133 N terminal like PD40 PF07676.7 ETO27299.1 - 0.008 15.8 0.1 0.9 9.2 0.0 2.7 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.9 ETO27299.1 - 0.009 14.8 0.1 0.16 10.7 0.0 2.0 1 1 0 1 1 1 1 Coatomer WD associated region Proteasome_A_N PF10584.4 ETO27299.1 - 0.023 13.9 0.2 5.4 6.4 0.0 3.0 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Nbas_N PF15492.1 ETO27299.1 - 0.029 13.4 0.3 5.1 6.1 0.0 2.4 1 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal TRA-1_regulated PF02343.11 ETO27299.1 - 0.075 12.5 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 TRA-1 regulated protein R03H10.4 Band_7 PF01145.20 ETO27300.1 - 2.1e-27 96.1 0.2 2.8e-27 95.7 0.1 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 ETO27300.1 - 0.00045 19.7 0.1 0.0008 18.9 0.1 1.4 1 1 0 1 1 1 1 SPFH domain-Band 7 family RRM_1 PF00076.17 ETO27302.1 - 7.7e-06 25.4 0.0 1.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO27302.1 - 3.2e-05 23.6 0.0 5.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO27302.1 - 0.0027 17.6 0.0 0.0051 16.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Flavi_NS1 PF00948.16 ETO27303.1 - 0.00045 18.7 2.5 0.00069 18.1 1.7 1.3 1 0 0 1 1 1 1 Flavivirus non-structural Protein NS1 Mucin PF01456.12 ETO27303.1 - 0.024 14.4 8.3 0.035 13.8 5.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.7 ETO27303.1 - 0.27 8.9 9.6 0.01 13.6 2.4 1.6 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.6 ETO27303.1 - 1.6 6.6 8.5 2 6.3 5.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 ETO27303.1 - 1.7 8.4 10.4 3.2 7.5 7.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF2407_C PF13373.1 ETO27303.1 - 9.6 6.1 8.2 0.46 10.3 1.1 1.9 2 0 0 2 2 2 0 DUF2407 C-terminal domain Abhydro_lipase PF04083.11 ETO27304.1 - 2.2e-21 74.9 0.0 4.5e-21 73.9 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 ETO27304.1 - 2.7e-06 27.1 0.0 4.7e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETO27304.1 - 2.6e-05 24.0 0.0 4.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETO27304.1 - 0.0046 16.8 0.0 0.007 16.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 ETO27304.1 - 0.1 11.5 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme ORC6 PF05460.8 ETO27305.1 - 0.022 13.8 11.6 0.029 13.4 8.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF1777 PF08648.7 ETO27305.1 - 0.85 9.3 57.4 1.8 8.2 39.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 ETO27305.1 - 1.3 7.4 34.6 1.5 7.2 24.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Macoilin PF09726.4 ETO27305.1 - 4.3 5.4 20.3 6.3 4.9 14.1 1.2 1 0 0 1 1 1 0 Transmembrane protein RRM_1 PF00076.17 ETO27306.1 - 6.4e-13 48.1 0.4 4e-11 42.3 0.3 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO27306.1 - 1.5e-10 40.8 0.3 2.4e-09 37.0 0.2 2.2 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO27306.1 - 7.2e-09 35.3 0.1 1.4e-08 34.4 0.1 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Elong_Iki1 PF10483.4 ETO27306.1 - 0.0068 15.8 0.1 0.0088 15.4 0.1 1.1 1 0 0 1 1 1 1 Elongator subunit Iki1 DUF4361 PF14274.1 ETO27306.1 - 0.048 13.3 0.0 0.069 12.7 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4361) DUF1644 PF07800.7 ETO27306.1 - 0.059 13.2 0.1 0.094 12.5 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) Nup35_RRM_2 PF14605.1 ETO27306.1 - 0.07 12.9 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif MitMem_reg PF13012.1 ETO27306.1 - 0.083 12.9 0.4 0.12 12.4 0.2 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function ABA_GPCR PF12430.3 ETO27307.1 - 0.082 12.0 0.4 0.55 9.3 0.0 2.2 1 1 2 3 3 3 0 Abscisic acid G-protein coupled receptor HEAT PF02985.17 ETO27307.1 - 0.097 12.8 0.0 0.86 9.8 0.0 2.6 2 0 0 2 2 2 0 HEAT repeat GAS PF13851.1 ETO27309.1 - 0.0036 16.5 11.5 0.0036 16.5 8.0 3.0 1 1 2 3 3 3 1 Growth-arrest specific micro-tubule binding Cep57_CLD_2 PF14197.1 ETO27309.1 - 0.022 14.6 1.7 0.022 14.6 1.2 3.0 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Gp58 PF07902.6 ETO27309.1 - 0.089 11.0 7.8 0.11 10.6 5.4 1.1 1 0 0 1 1 1 0 gp58-like protein Peptidase_C10 PF01640.12 ETO27309.1 - 0.55 9.9 3.3 0.86 9.3 2.3 1.3 1 0 0 1 1 1 0 Peptidase C10 family Occludin_ELL PF07303.8 ETO27309.1 - 0.91 10.2 14.9 0.077 13.7 2.2 2.7 1 1 3 4 4 4 0 Occludin homology domain IncA PF04156.9 ETO27309.1 - 1.3 8.6 22.8 2.9 7.4 15.4 1.8 1 1 0 1 1 1 0 IncA protein Jnk-SapK_ap_N PF09744.4 ETO27309.1 - 2.5 8.0 18.4 6.7 6.6 7.9 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF4140 PF13600.1 ETO27309.1 - 6.8 7.2 12.5 0.67 10.4 3.9 2.3 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Adaptin_binding PF10199.4 ETO27310.1 - 0.074 13.3 3.3 0.1 12.8 2.3 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 CENP-F_leu_zip PF10473.4 ETO27310.1 - 0.64 9.8 9.8 2.2 8.1 1.9 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMCO5 PF14992.1 ETO27310.1 - 0.95 8.5 12.1 58 2.6 8.4 2.0 1 1 0 1 1 1 0 TMCO5 family DUF947 PF06102.7 ETO27310.1 - 7.6 6.3 11.4 1.9 8.3 2.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF947) Cortex-I_coil PF09304.5 ETO27310.1 - 9.9 6.2 11.7 9.9 6.2 2.1 2.1 2 0 0 2 2 2 0 Cortexillin I, coiled coil GAT PF03127.9 ETO27311.1 - 0.66 9.9 6.3 3.7 7.5 4.4 2.0 1 1 0 1 1 1 0 GAT domain Ly49 PF08391.5 ETO27311.1 - 6.1 6.9 11.1 3.9 7.6 3.3 2.5 1 1 2 3 3 3 0 Ly49-like protein, N-terminal region CENP-F_leu_zip PF10473.4 ETO27312.1 - 3.9 7.3 22.0 0.31 10.8 4.3 4.3 4 1 0 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DnaJ PF00226.26 ETO27313.1 - 5.5e-22 77.2 0.4 5.5e-22 77.2 0.3 2.1 2 0 0 2 2 2 1 DnaJ domain CTDII PF01556.13 ETO27313.1 - 8.2e-14 51.2 4.8 1.5e-08 34.3 0.0 5.6 6 1 0 6 6 6 3 DnaJ C terminal domain NIF PF03031.13 ETO27314.1 - 7.3e-44 149.2 3.1 3.5e-43 147.0 1.4 2.3 2 1 0 2 2 2 1 NLI interacting factor-like phosphatase DUF1600 PF07667.6 ETO27314.1 - 0.036 14.1 0.1 0.13 12.3 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1600) DUF1424 PF07232.6 ETO27314.1 - 0.21 10.3 0.0 0.37 9.5 0.0 1.3 1 0 0 1 1 1 0 Putative rep protein (DUF1424) Acyl-CoA_dh_1 PF00441.19 ETO27315.1 - 1.1e-40 139.1 0.1 2.6e-40 137.9 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 ETO27315.1 - 1.4e-19 70.6 0.1 6.7e-17 61.9 0.1 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 ETO27315.1 - 9.9e-11 40.9 0.0 1.9e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HpaB_N PF11794.3 ETO27315.1 - 0.075 12.4 1.8 1 8.6 0.2 2.6 2 1 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF1878 PF08963.5 ETO27316.1 - 0.036 14.2 0.2 0.036 14.2 0.1 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1878) DUF3323 PF11796.3 ETO27316.1 - 0.061 12.6 0.3 0.11 11.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) PC4 PF02229.11 ETO27316.1 - 0.065 12.4 0.0 0.2 10.8 0.0 1.8 1 0 0 1 1 1 0 Transcriptional Coactivator p15 (PC4) XkdN PF08890.6 ETO27316.1 - 0.48 10.1 14.8 0.022 14.5 5.3 2.4 2 1 0 2 2 2 0 Phage XkdN-like protein Hom_end_hint PF05203.11 ETO27316.1 - 1.9 8.1 8.2 2.4 7.8 5.7 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint MMR1 PF08505.5 ETO27316.1 - 5.7 6.8 11.5 10 6.0 8.0 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein PH PF00169.24 ETO27317.1 - 1.2e-06 28.6 1.7 1.2e-06 28.6 1.2 1.9 2 1 0 2 2 2 1 PH domain PH_11 PF15413.1 ETO27317.1 - 0.016 15.4 2.0 0.016 15.4 1.4 2.3 1 1 1 2 2 2 0 Pleckstrin homology domain NNMT_PNMT_TEMT PF01234.12 ETO27317.1 - 0.037 12.9 0.2 0.052 12.5 0.1 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family DUF1539 PF07560.6 ETO27318.1 - 0.23 11.3 4.8 0.32 10.8 0.9 2.2 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1539) DUF2951 PF11166.3 ETO27319.1 - 5.1e-05 23.0 2.3 5.1e-05 23.0 1.6 3.4 2 1 1 3 3 2 1 Protein of unknown function (DUF2951) CENP-F_leu_zip PF10473.4 ETO27319.1 - 0.00013 21.7 51.2 0.0098 15.7 7.1 3.0 1 1 2 3 3 3 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 ETO27319.1 - 0.0063 16.1 21.3 0.0063 16.1 14.8 2.9 1 1 2 3 3 3 1 IncA protein GAS PF13851.1 ETO27319.1 - 0.0066 15.6 28.6 0.0066 15.6 19.8 3.1 1 1 2 3 3 3 2 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 ETO27319.1 - 0.01 15.0 4.9 0.12 11.5 0.6 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF641 PF04859.7 ETO27319.1 - 0.011 15.4 8.4 0.011 15.4 5.8 3.2 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Filament PF00038.16 ETO27319.1 - 0.031 13.7 42.6 0.032 13.6 7.8 2.8 1 1 2 3 3 3 0 Intermediate filament protein Atg14 PF10186.4 ETO27319.1 - 0.11 11.3 40.0 0.042 12.7 13.5 2.4 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ERM PF00769.14 ETO27319.1 - 0.32 10.4 47.3 4.3 6.7 8.2 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF812 PF05667.6 ETO27319.1 - 0.33 9.4 37.9 0.83 8.0 11.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF812) ATG16 PF08614.6 ETO27319.1 - 0.47 10.2 48.7 0.19 11.5 8.3 3.0 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) APG6 PF04111.7 ETO27319.1 - 0.57 9.1 51.4 0.91 8.5 15.3 2.5 1 1 2 3 3 3 0 Autophagy protein Apg6 DUF3584 PF12128.3 ETO27319.1 - 0.69 7.1 38.8 0.94 6.7 26.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CCDC155 PF14662.1 ETO27319.1 - 0.81 9.2 42.5 0.21 11.1 18.2 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 TMF_DNA_bd PF12329.3 ETO27319.1 - 0.84 9.4 55.6 0.093 12.5 7.8 5.6 1 1 4 6 6 6 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.3 ETO27319.1 - 0.89 9.4 50.5 0.65 9.8 6.1 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.5 ETO27319.1 - 1.9 8.6 38.9 1.3 9.1 9.4 2.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Mod_r PF07200.8 ETO27319.1 - 1.9 8.4 46.1 13 5.7 15.3 3.6 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF2968 PF11180.3 ETO27319.1 - 2.1 7.6 27.5 0.44 9.9 6.7 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) Tropomyosin_1 PF12718.2 ETO27319.1 - 2.1 8.1 54.0 10 5.9 21.7 3.0 1 1 1 2 2 2 0 Tropomyosin like CALCOCO1 PF07888.6 ETO27319.1 - 3.6 5.7 41.4 0.31 9.2 18.0 2.1 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like WEMBL PF05701.6 ETO27319.1 - 3.8 5.8 39.4 7.8 4.8 27.3 1.4 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Tropomyosin PF00261.15 ETO27319.1 - 4 6.4 44.5 0.14 11.1 9.0 3.1 1 1 2 3 3 3 0 Tropomyosin AAA_6 PF12774.2 ETO27320.1 - 5.1e-91 304.3 1.1 1e-90 303.2 0.1 2.0 3 0 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 ETO27320.1 - 3.1e-18 65.8 0.0 1.4e-08 34.5 0.0 4.2 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 ETO27320.1 - 6.1e-11 41.9 0.0 2.8e-10 39.7 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_16 PF13191.1 ETO27320.1 - 1e-08 35.3 0.0 0.077 12.9 0.0 3.5 3 0 0 3 3 3 3 AAA ATPase domain AAA PF00004.24 ETO27320.1 - 2.1e-08 34.4 0.1 0.045 13.9 0.0 4.0 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETO27320.1 - 4.1e-08 33.4 0.0 0.36 10.9 0.0 3.7 3 0 0 3 3 3 3 AAA domain AAA_19 PF13245.1 ETO27320.1 - 1.6e-07 30.9 0.3 0.75 9.5 0.0 3.4 3 0 0 3 3 3 3 Part of AAA domain AAA_33 PF13671.1 ETO27320.1 - 6e-07 29.4 0.9 0.0081 16.0 0.0 3.7 4 0 0 4 4 3 2 AAA domain RNA_helicase PF00910.17 ETO27320.1 - 3e-06 27.3 0.2 0.95 9.6 0.0 4.1 4 0 0 4 4 3 1 RNA helicase AAA_17 PF13207.1 ETO27320.1 - 4.3e-05 24.3 0.7 0.31 11.8 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 ETO27320.1 - 4.7e-05 23.2 0.0 2.1 8.2 0.0 4.4 4 0 0 4 4 4 2 AAA domain AAA_11 PF13086.1 ETO27320.1 - 8e-05 22.3 0.9 0.71 9.3 0.0 3.5 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.1 ETO27320.1 - 0.00016 21.9 0.0 0.78 10.0 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.1 ETO27320.1 - 0.00023 20.8 0.1 5 6.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.16 ETO27320.1 - 0.0012 18.0 0.4 0.014 14.5 0.0 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 ETO27320.1 - 0.0012 17.9 0.1 4 6.4 0.0 3.4 3 0 0 3 3 3 1 Zeta toxin AAA_29 PF13555.1 ETO27320.1 - 0.0017 17.8 0.1 1.7 8.2 0.0 2.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.7 ETO27320.1 - 0.0028 17.3 0.1 0.79 9.3 0.0 3.7 3 0 0 3 3 3 1 NACHT domain Arch_ATPase PF01637.13 ETO27320.1 - 0.0058 16.3 0.0 0.63 9.6 0.0 3.3 3 0 0 3 3 3 1 Archaeal ATPase AAA_24 PF13479.1 ETO27320.1 - 0.0099 15.4 1.5 1.9 8.0 0.0 3.6 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 ETO27320.1 - 0.012 15.0 0.2 1.6 8.1 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Miro PF08477.8 ETO27320.1 - 0.02 15.4 0.1 0.26 11.7 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein Ras PF00071.17 ETO27320.1 - 0.02 14.2 0.1 0.11 11.8 0.1 2.2 2 0 0 2 2 2 0 Ras family AAA_28 PF13521.1 ETO27320.1 - 0.035 14.0 0.3 32 4.4 0.0 3.8 4 0 0 4 4 4 0 AAA domain FAM150 PF15129.1 ETO27320.1 - 0.045 13.6 0.8 0.1 12.5 0.6 1.5 1 0 0 1 1 1 0 FAM150 family IstB_IS21 PF01695.12 ETO27320.1 - 0.064 12.6 0.1 13 5.1 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF853 PF05872.7 ETO27320.1 - 0.18 10.1 2.0 20 3.3 0.0 3.2 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF853) UvrD-helicase PF00580.16 ETO27320.1 - 0.24 10.6 0.0 0.24 10.6 0.0 2.5 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain DUF2075 PF09848.4 ETO27320.1 - 0.52 9.2 2.9 0.59 9.0 0.0 2.3 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.4 ETO27320.1 - 0.55 8.7 5.3 4.5 5.7 0.0 3.2 4 0 0 4 4 4 0 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_1 PF03029.12 ETO27320.1 - 5.5 6.4 6.8 8.2 5.8 0.0 3.7 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein DUF87 PF01935.12 ETO27320.1 - 7.4 6.3 10.1 15 5.3 0.0 4.0 5 0 0 5 5 4 0 Domain of unknown function DUF87 DUF1284 PF06935.6 ETO27321.1 - 0.19 11.9 5.7 0.8 9.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1284) APG6 PF04111.7 ETO27322.1 - 2.6 7.0 31.1 4.1 6.3 21.1 1.6 1 1 0 1 1 1 0 Autophagy protein Apg6 ACCA PF03255.9 ETO27322.1 - 8.7 5.8 17.7 6.2 6.3 4.1 2.3 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF3584 PF12128.3 ETO27322.1 - 8.9 3.4 34.4 11 3.2 23.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PepSY_2 PF13670.1 ETO27323.1 - 0.54 10.2 8.0 0.16 11.8 2.7 2.1 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain TPR_14 PF13428.1 ETO27324.1 - 1.5e-33 112.2 15.3 0.0015 18.9 0.1 13.5 6 3 8 14 14 14 10 Tetratricopeptide repeat TPR_19 PF14559.1 ETO27324.1 - 1.8e-21 76.2 6.3 1.1e-05 25.6 0.0 9.3 5 4 4 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO27324.1 - 7.5e-12 45.5 6.1 1.3 9.7 0.0 8.2 7 2 1 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO27324.1 - 1.9e-10 39.8 7.1 3.3 7.8 0.0 10.0 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO27324.1 - 3.5e-09 36.1 12.0 0.26 10.9 0.1 8.4 3 2 5 10 10 10 4 TPR repeat TPR_9 PF13371.1 ETO27324.1 - 2.5e-07 30.4 7.0 0.15 11.9 0.0 4.7 4 1 0 4 4 4 3 Tetratricopeptide repeat Suf PF05843.9 ETO27324.1 - 3.9e-07 30.0 0.0 1.3 8.7 0.0 4.8 5 0 0 5 5 5 3 Suppressor of forked protein (Suf) TPR_17 PF13431.1 ETO27324.1 - 1.9e-05 24.4 1.4 3.1 8.2 0.0 8.3 10 1 0 10 10 10 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO27324.1 - 0.00058 19.7 7.5 26 4.8 0.0 6.9 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO27324.1 - 0.00086 19.6 5.6 1.4e+02 3.2 0.0 8.3 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_21 PF09976.4 ETO27324.1 - 0.096 12.6 6.7 0.5 10.3 0.5 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_S49 PF01343.13 ETO27326.1 - 3e-31 108.2 0.0 4.8e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S49 AAR2 PF05282.6 ETO27330.1 - 6.5e-53 179.9 15.6 1.7e-52 178.5 10.8 1.6 1 1 0 1 1 1 1 AAR2 protein MIP-T3 PF10243.4 ETO27330.1 - 0.0098 14.4 10.2 0.015 13.7 7.1 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Vac7 PF12751.2 ETO27331.1 - 0.48 9.2 12.2 0.6 8.9 8.4 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 DUF4591 PF15261.1 ETO27331.1 - 8.4 6.6 13.2 3.2 7.9 6.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4591) Atg14 PF10186.4 ETO27332.1 - 0.14 11.0 32.7 0.18 10.7 13.8 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Rubis-subs-bind PF09273.6 ETO27333.1 - 3.3e-10 39.9 0.0 1.8e-09 37.6 0.0 2.2 2 1 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.23 ETO27333.1 - 0.00011 22.5 0.0 0.00022 21.5 0.0 1.5 1 0 0 1 1 1 1 SET domain ERCC4 PF02732.10 ETO27333.1 - 0.029 14.1 0.0 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 ERCC4 domain DUF3376 PF11856.3 ETO27333.1 - 0.12 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3376) TPR_11 PF13414.1 ETO27334.1 - 7.8e-13 47.8 1.2 6.3e-12 44.9 0.6 2.1 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 ETO27334.1 - 1.2e-07 31.0 2.8 0.0078 15.7 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO27334.1 - 3.2e-07 29.7 1.3 0.015 15.1 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO27334.1 - 0.00011 22.0 0.8 0.42 10.5 0.9 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO27334.1 - 0.00025 20.6 1.0 0.11 12.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat FXR1P_C PF12235.3 ETO27334.1 - 0.0028 17.7 1.8 0.0033 17.5 1.3 1.2 1 0 0 1 1 1 1 Fragile X-related 1 protein C terminal TPR_14 PF13428.1 ETO27334.1 - 0.071 13.7 0.1 30 5.6 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat AAA_13 PF13166.1 ETO27335.1 - 0.00015 20.3 43.2 0.00015 20.3 30.0 3.1 1 1 2 3 3 3 1 AAA domain TPR_MLP1_2 PF07926.7 ETO27335.1 - 0.0016 18.1 26.2 0.0016 18.1 18.1 6.1 1 1 3 4 4 2 2 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.14 ETO27335.1 - 0.0018 16.1 98.4 0.0024 15.6 2.6 3.4 2 1 1 3 3 3 3 Myosin tail GAS PF13851.1 ETO27335.1 - 0.003 16.7 16.9 0.003 16.7 11.7 5.2 2 2 3 5 5 5 2 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.16 ETO27335.1 - 0.0056 16.6 11.7 0.02 14.8 2.7 10.3 4 2 6 10 10 9 3 bZIP transcription factor Reo_sigmaC PF04582.7 ETO27335.1 - 0.0089 15.2 24.5 0.033 13.3 0.6 3.9 1 1 2 4 4 4 3 Reovirus sigma C capsid protein ATG16 PF08614.6 ETO27335.1 - 0.078 12.7 92.9 0.089 12.5 9.8 5.1 1 1 4 5 5 5 0 Autophagy protein 16 (ATG16) IncA PF04156.9 ETO27335.1 - 0.15 11.6 92.5 0.013 15.1 16.4 4.8 1 1 3 4 4 4 0 IncA protein FUSC PF04632.7 ETO27335.1 - 0.19 10.1 3.4 0.34 9.2 2.4 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family UPF0147 PF03685.8 ETO27335.1 - 5.2 7.0 14.7 0.43 10.4 1.8 4.5 4 2 0 4 4 4 0 Uncharacterised protein family (UPF0147) AAA_27 PF13514.1 ETO27335.1 - 7.1 4.1 67.6 0.18 9.4 36.3 2.2 1 1 1 2 2 2 0 AAA domain IncA PF04156.9 ETO27336.1 - 0.0081 15.7 15.6 0.0081 15.7 10.8 3.4 1 1 2 3 3 3 1 IncA protein Reo_sigmaC PF04582.7 ETO27336.1 - 0.62 9.1 15.8 1.1 8.3 0.8 3.1 1 1 1 3 3 3 0 Reovirus sigma C capsid protein DUF812 PF05667.6 ETO27336.1 - 1.2 7.5 53.0 0.62 8.5 16.7 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF812) RhoGAP PF00620.22 ETO27337.1 - 1.4e-18 66.9 0.5 3e-18 65.8 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.24 ETO27337.1 - 0.00011 22.3 0.5 0.00026 21.1 0.0 1.9 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 ETO27337.1 - 0.007 16.6 0.3 0.018 15.2 0.2 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Borrelia_orfD PF02999.9 ETO27338.1 - 0.096 12.8 2.8 0.12 12.5 1.0 1.8 2 0 0 2 2 2 0 Borrelia orf-D family Sec7_N PF12783.2 ETO27341.1 - 3.2e-32 111.2 1.1 3e-30 104.8 0.7 3.2 1 1 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal SAM_1 PF00536.25 ETO27342.1 - 6.5e-15 55.0 0.1 1e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO27342.1 - 6.7e-14 51.4 0.1 1.1e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 ETO27342.1 - 0.026 14.2 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain PA-IIL PF07472.6 ETO27342.1 - 0.26 11.5 1.8 6.2 7.0 0.2 2.4 2 0 0 2 2 2 0 Fucose-binding lectin II (PA-IIL) Epimerase PF01370.16 ETO27343.1 - 6e-16 58.5 0.0 1.3e-15 57.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 ETO27343.1 - 1.6e-07 30.5 0.0 3.6e-07 29.3 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 ETO27343.1 - 2.1e-06 26.8 0.0 2.1e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 ETO27343.1 - 0.0007 18.3 0.0 0.0017 17.1 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 ETO27343.1 - 0.021 14.8 0.0 0.042 13.8 0.0 1.6 1 1 0 1 1 1 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 ETO27343.1 - 0.024 13.5 0.6 0.057 12.3 0.4 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.20 ETO27343.1 - 0.026 14.4 0.0 0.061 13.2 0.0 1.7 1 1 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.15 ETO27343.1 - 0.066 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Arm PF00514.18 ETO27344.1 - 9.9e-21 72.7 12.6 7e-07 28.8 0.2 7.3 6 1 1 7 7 7 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 ETO27344.1 - 1.3e-10 41.3 5.8 5.2e-05 23.4 0.2 4.2 2 1 2 4 4 4 3 HEAT repeats HEAT PF02985.17 ETO27344.1 - 3.9e-10 38.9 3.0 0.04 14.0 0.0 5.3 6 0 0 6 6 5 3 HEAT repeat Proteasom_PSMB PF10508.4 ETO27344.1 - 8.9e-08 30.8 1.9 5.2e-07 28.3 0.6 2.1 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit HEAT_EZ PF13513.1 ETO27344.1 - 1.3e-06 28.6 7.4 0.045 14.2 0.0 5.1 3 2 2 5 5 5 3 HEAT-like repeat Adaptin_N PF01602.15 ETO27344.1 - 8.3e-05 21.0 6.9 0.0046 15.3 1.0 2.7 3 0 0 3 3 3 2 Adaptin N terminal region DNA_alkylation PF08713.6 ETO27344.1 - 0.00058 19.4 0.4 1.8 8.0 0.0 3.1 2 1 1 3 3 3 2 DNA alkylation repair enzyme Vac14_Fab1_bd PF12755.2 ETO27344.1 - 0.01 16.2 0.8 0.046 14.1 0.1 2.5 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 ETO27344.1 - 0.011 15.6 1.3 0.14 12.0 0.3 2.8 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.11 ETO27344.1 - 0.067 13.6 3.7 15 6.3 0.0 4.4 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.3 ETO27344.1 - 0.072 13.0 0.6 7.4 6.5 0.0 2.7 2 1 0 2 2 2 0 V-ATPase subunit H WD40 PF00400.27 ETO27345.1 - 1e-49 164.6 13.0 9.5e-11 41.1 0.2 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO27345.1 - 2.2e-10 39.3 3.8 0.0017 16.5 0.0 4.8 1 1 3 5 5 5 5 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO27345.1 - 0.00048 19.8 2.5 0.37 10.5 0.1 3.9 1 1 3 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Ricin_B_lectin PF00652.17 ETO27345.1 - 0.04 13.9 0.8 0.04 13.9 0.5 2.8 2 1 1 3 3 3 0 Ricin-type beta-trefoil lectin domain WD40 PF00400.27 ETO27346.1 - 5.8e-93 301.7 19.4 7.1e-14 51.0 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO27346.1 - 2.6e-08 32.4 9.6 0.015 13.4 0.3 5.3 1 1 4 5 5 5 5 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO27346.1 - 5.4e-06 26.0 0.2 9.3e-05 22.0 0.1 2.3 1 1 1 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO27346.1 - 2.8e-05 22.6 1.3 0.03 12.6 0.0 3.0 1 1 2 3 3 3 3 Cytochrome D1 heme domain BBS2_Mid PF14783.1 ETO27346.1 - 0.00033 20.3 3.8 2.6 7.8 0.0 4.9 2 2 3 5 5 5 2 Ciliary BBSome complex subunit 2, middle region DUF1258 PF06869.7 ETO27346.1 - 0.0031 16.6 0.8 9.3 5.2 0.1 3.5 1 1 1 3 3 3 3 Protein of unknown function (DUF1258) Mid2 PF04478.7 ETO27346.1 - 0.09 12.1 4.4 3.4 7.0 0.0 4.3 4 1 1 5 5 5 0 Mid2 like cell wall stress sensor Proteasome_A_N PF10584.4 ETO27346.1 - 0.22 10.8 2.3 5.3 6.4 0.0 3.2 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature PD40 PF07676.7 ETO27346.1 - 1.3 8.8 7.7 40 4.0 0.0 5.3 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat SAGA-Tad1 PF12767.2 ETO27349.1 - 4.8e-11 42.8 15.2 4.8e-11 42.8 10.6 2.8 2 2 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit ubiquitin PF00240.18 ETO27351.1 - 0.00074 18.8 0.5 0.0015 17.8 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF4162 PF13732.1 ETO27351.1 - 0.17 12.4 0.5 0.29 11.6 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) Pex14_N PF04695.8 ETO27353.1 - 4.7e-05 23.4 5.1 0.00016 21.6 3.4 1.8 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3647 PF12363.3 ETO27353.1 - 0.021 14.8 1.8 0.035 14.1 1.2 1.3 1 0 0 1 1 1 0 Phage protein MecA PF05389.7 ETO27353.1 - 0.24 10.9 4.1 0.38 10.2 2.8 1.2 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) DUF2229 PF09989.4 ETO27353.1 - 0.58 9.5 2.5 0.97 8.8 1.7 1.3 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) PUB PF09409.5 ETO27354.1 - 4.7e-07 29.4 0.0 1e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 PUB domain Drf_GBD PF06371.8 ETO27354.1 - 0.0045 16.3 0.0 0.0096 15.3 0.0 1.6 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain SART-1 PF03343.8 ETO27355.1 - 0.13 10.5 8.7 0.14 10.4 6.0 1.0 1 0 0 1 1 1 0 SART-1 family SOG2 PF10428.4 ETO27356.1 - 0.0012 17.5 0.7 0.0016 17.2 0.5 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein Sec34 PF04136.10 ETO27356.1 - 0.076 12.7 3.6 0.84 9.3 0.1 2.5 3 0 0 3 3 3 0 Sec34-like family DUF4134 PF13572.1 ETO27356.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4134) TPR_MLP1_2 PF07926.7 ETO27356.1 - 0.16 11.7 2.8 0.86 9.3 1.8 2.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein HAP1_N PF04849.8 ETO27356.1 - 0.17 10.7 7.5 0.78 8.6 5.1 2.1 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Bacillus_HBL PF05791.6 ETO27356.1 - 0.35 10.2 3.7 0.85 8.9 0.1 2.7 3 1 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) CENP-F_leu_zip PF10473.4 ETO27356.1 - 0.63 9.8 8.3 3.1 7.6 0.6 2.8 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.16 ETO27356.1 - 2 8.4 7.0 28 4.7 0.1 4.0 4 1 1 5 5 5 0 bZIP transcription factor DUF4187 PF13821.1 ETO27356.1 - 8.8 6.0 6.6 3.3 7.3 0.5 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4187) MHYT PF03707.11 ETO27357.1 - 2.7e-30 104.2 19.9 8.9e-14 51.3 2.3 4.2 4 0 0 4 4 4 3 Bacterial signalling protein N terminal repeat Ctr PF04145.10 ETO27357.1 - 0.026 14.5 0.1 0.13 12.2 0.1 2.3 1 1 0 1 1 1 0 Ctr copper transporter family CAAD PF14159.1 ETO27357.1 - 2.2 7.9 5.4 0.72 9.5 0.4 2.4 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF3021 PF11457.3 ETO27357.1 - 6.9 6.5 14.1 0.039 13.8 1.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3021) Toxin_48 PF15528.1 ETO27359.1 - 0.032 14.1 1.1 0.032 14.1 0.7 2.0 2 0 0 2 2 2 0 Putative toxin 48 UQ_con PF00179.21 ETO27360.1 - 1.5e-05 24.4 0.7 0.00015 21.1 0.5 2.2 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF3799 PF12684.2 ETO27360.1 - 0.22 10.8 1.2 0.3 10.4 0.8 1.2 1 0 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) DUF1761 PF08570.5 ETO27361.1 - 0.19 11.7 0.1 0.44 10.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1761) Ctr PF04145.10 ETO27362.1 - 5.7 6.9 5.4 1.1e+02 2.8 2.9 3.0 2 1 0 2 2 2 0 Ctr copper transporter family Malic_M PF03949.10 ETO27365.1 - 0.0032 17.0 1.0 0.0083 15.7 0.7 1.6 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain NAD_binding_9 PF13454.1 ETO27365.1 - 0.0044 16.8 0.1 0.01 15.5 0.0 1.6 1 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 ETO27365.1 - 0.085 12.8 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETO27365.1 - 0.094 12.5 0.8 0.15 11.8 0.5 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETO27365.1 - 0.11 11.3 0.1 0.17 10.7 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 ETO27365.1 - 0.13 11.1 1.8 1.6 7.4 0.2 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.22 ETO27366.1 - 0.14 12.6 0.1 0.39 11.1 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETO27367.1 - 2.7e-07 30.6 0.0 0.00018 21.4 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Annexin PF00191.15 ETO27368.1 - 6.3e-13 48.4 0.1 1.1e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Annexin Rot1 PF10681.4 ETO27368.1 - 0.033 13.5 0.2 0.037 13.3 0.1 1.1 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal U1snRNP70_N PF12220.3 ETO27368.1 - 0.4 11.0 5.0 0.64 10.3 3.5 1.3 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Ribosomal_60s PF00428.14 ETO27368.1 - 2.8 8.4 11.5 4.5 7.7 8.0 1.5 1 1 0 1 1 1 0 60s Acidic ribosomal protein Anoctamin PF04547.7 ETO27369.1 - 0.011 14.4 1.6 0.012 14.2 1.1 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel PBP1_TM PF14812.1 ETO27369.1 - 0.73 10.1 10.4 1.1 9.5 5.6 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.7 ETO27369.1 - 0.76 8.9 6.7 1.2 8.3 4.6 1.4 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.5 ETO27369.1 - 9.1 6.5 14.5 9 6.6 7.8 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain LMBR1 PF04791.11 ETO27370.1 - 4.7e-08 32.0 0.6 7.7e-08 31.3 0.4 1.5 1 1 0 1 1 1 1 LMBR1-like membrane protein CtIP_N PF10482.4 ETO27370.1 - 0.043 13.6 3.5 0.19 11.4 2.4 2.0 1 1 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain DUF1469 PF07332.6 ETO27370.1 - 0.077 12.7 0.4 0.12 12.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) PH_11 PF15413.1 ETO27371.1 - 0.012 15.9 0.1 0.031 14.5 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain PH PF00169.24 ETO27371.1 - 0.037 14.2 0.2 0.7 10.1 0.0 2.2 2 0 0 2 2 2 0 PH domain WD40 PF00400.27 ETO27372.1 - 1.6e-78 256.0 20.6 5.1e-13 48.3 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO27372.1 - 4.6e-13 49.3 0.1 5.9e-05 22.8 0.0 3.5 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 ETO27372.1 - 7.5e-09 34.8 8.4 0.025 13.3 0.3 5.8 1 1 4 6 6 6 4 Nup133 N terminal like Nup160 PF11715.3 ETO27372.1 - 5.4e-07 28.1 5.2 0.21 9.6 0.0 5.5 1 1 4 5 5 5 3 Nucleoporin Nup120/160 PD40 PF07676.7 ETO27372.1 - 7.2e-07 28.7 5.9 6.8 6.4 0.0 5.8 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO27372.1 - 2.3e-06 26.1 0.0 0.0068 14.7 0.0 2.9 2 1 1 3 3 3 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO27372.1 - 0.00016 21.2 0.0 0.23 10.8 0.0 2.8 2 2 0 2 2 2 2 PQQ-like domain Ricin_B_lectin PF00652.17 ETO27372.1 - 0.026 14.5 0.3 0.17 11.9 0.0 2.4 1 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain Resistin PF06954.6 ETO27372.1 - 0.027 14.7 0.3 1.4e+02 2.8 0.0 4.4 2 1 3 5 5 5 0 Resistin Proteasome_A_N PF10584.4 ETO27372.1 - 0.037 13.3 7.7 22 4.4 0.3 4.7 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature DUF3601 PF12208.3 ETO27372.1 - 0.047 13.6 0.0 12 5.9 0.0 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF3601) DUF2415 PF10313.4 ETO27372.1 - 0.14 11.8 0.2 25 4.6 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) POLO_box PF00659.13 ETO27372.1 - 0.14 12.1 0.0 17 5.4 0.0 2.6 2 0 0 2 2 2 0 POLO box duplicated region Hira PF07569.6 ETO27372.1 - 0.15 11.2 0.3 4.3 6.4 0.0 3.1 2 2 2 4 4 4 0 TUP1-like enhancer of split DUF2183 PF09949.4 ETO27373.1 - 1.9 8.4 4.8 1 9.3 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) MDFI PF15316.1 ETO27374.1 - 1.5 8.7 5.5 5.4 6.9 3.7 1.7 1 1 0 1 1 1 0 MyoD family inhibitor SprA-related PF12118.3 ETO27374.1 - 2.5 7.3 9.5 3 7.0 6.6 1.0 1 0 0 1 1 1 0 SprA-related family zf-CCHC_2 PF13696.1 ETO27375.1 - 4.5e-07 29.2 4.1 7.4e-07 28.5 2.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 ETO27375.1 - 6.4e-05 22.6 2.5 0.00012 21.8 1.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 ETO27375.1 - 0.016 14.9 0.2 0.04 13.6 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle Ank_2 PF12796.2 ETO27376.1 - 1.8e-07 31.3 2.5 0.0026 18.0 0.1 2.6 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO27376.1 - 3.2e-07 30.7 0.8 0.00036 20.9 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO27376.1 - 1.4e-05 24.8 1.6 0.42 11.0 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.25 ETO27376.1 - 0.0016 18.1 0.3 2.7 7.9 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat DUF4518 PF15008.1 ETO27376.1 - 0.013 14.5 0.5 0.021 13.8 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) DUF4119 PF13494.1 ETO27376.1 - 0.042 13.8 1.4 1.3 9.0 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function, B. Theta Gene description (DUF4119) Ank_5 PF13857.1 ETO27376.1 - 0.074 13.3 2.5 3.9 7.8 0.2 2.9 2 1 0 2 2 2 0 Ankyrin repeats (many copies) FtsK_SpoIIIE_N PF12538.3 ETO27376.1 - 0.55 10.3 4.2 2.6 8.1 0.5 2.3 2 0 0 2 2 2 0 DNA transporter LRS4 PF10422.4 ETO27376.1 - 2 7.7 6.3 1.3 8.3 1.8 2.0 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 DsrD PF08679.6 ETO27376.1 - 4.6 7.3 6.5 3.2 7.8 0.0 2.8 2 1 1 3 3 3 0 Dissimilatory sulfite reductase D (DsrD) DUF1428 PF07237.6 ETO27377.1 - 0.019 14.8 1.0 0.042 13.7 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) MA3 PF02847.12 ETO27378.1 - 3.7e-18 65.2 4.1 1.1e-17 63.7 1.5 2.3 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.14 ETO27379.1 - 7.2e-06 25.5 0.1 1.2e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 MIF4G domain TrmE_N PF10396.4 ETO27379.1 - 0.00086 19.2 0.0 0.0021 17.9 0.0 1.6 1 1 0 1 1 1 1 GTP-binding protein TrmE N-terminus CD99L2 PF12301.3 ETO27379.1 - 0.051 13.2 1.0 0.077 12.6 0.7 1.3 1 0 0 1 1 1 0 CD99 antigen like protein 2 zf-C2H2_jaz PF12171.3 ETO27379.1 - 0.082 13.0 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding WD40 PF00400.27 ETO27380.1 - 3.6e-81 264.3 23.2 3.5e-13 48.8 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO27380.1 - 1.8e-08 33.0 3.5 0.0004 18.6 0.6 3.9 1 1 0 2 2 2 2 Nucleoporin Nup120/160 DUF1258 PF06869.7 ETO27380.1 - 3.2e-08 32.9 0.5 0.39 9.7 0.0 4.6 1 1 2 4 4 4 3 Protein of unknown function (DUF1258) eIF2A PF08662.6 ETO27380.1 - 1.7e-05 24.6 0.0 0.028 14.1 0.0 2.8 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO27380.1 - 0.0009 17.6 0.7 0.69 8.1 0.0 3.4 1 1 3 4 4 4 3 Cytochrome D1 heme domain Resistin PF06954.6 ETO27380.1 - 0.0018 18.5 1.7 29 5.0 0.0 4.7 3 2 2 5 5 5 0 Resistin PD40 PF07676.7 ETO27380.1 - 0.0061 16.2 11.4 8 6.2 0.1 5.7 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO27380.1 - 0.0066 15.2 4.1 0.31 9.7 0.4 3.9 1 1 1 2 2 2 1 Nup133 N terminal like Hira PF07569.6 ETO27380.1 - 0.051 12.7 0.1 0.67 9.1 0.0 2.7 3 0 0 3 3 3 0 TUP1-like enhancer of split Ricin_B_lectin PF00652.17 ETO27380.1 - 0.19 11.7 1.2 1.5 8.8 0.2 2.6 1 1 2 3 3 3 0 Ricin-type beta-trefoil lectin domain WD40 PF00400.27 ETO27381.1 - 4.9e-58 191.0 19.4 2.1e-11 43.2 0.0 7.2 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO27381.1 - 1.3e-09 36.7 4.0 0.00051 18.3 0.2 3.7 2 1 2 4 4 4 3 Nucleoporin Nup120/160 MIP PF00230.15 ETO27383.1 - 3.5e-24 85.5 6.6 4.6e-24 85.1 4.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF4203 PF13886.1 ETO27383.1 - 0.016 14.6 5.0 0.027 13.9 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) DUF4231 PF14015.1 ETO27383.1 - 0.054 13.4 0.6 0.26 11.2 0.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Peptidase_U4 PF03419.8 ETO27383.1 - 0.09 11.8 2.3 0.13 11.2 1.6 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA rpo30_N PF12410.3 ETO27385.1 - 0.034 13.7 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase 30kDa subunit FRG PF08867.6 ETO27385.1 - 0.077 13.5 1.4 2.2 8.8 0.2 2.4 2 0 0 2 2 2 0 FRG domain Mito_fiss_reg PF05308.6 ETO27386.1 - 0.0049 16.2 3.7 0.0049 16.2 2.6 1.8 2 0 0 2 2 2 1 Mitochondrial fission regulator DUF2796 PF10986.3 ETO27386.1 - 0.03 14.3 3.6 0.057 13.3 2.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Nucleoplasmin PF03066.10 ETO27386.1 - 0.086 12.3 4.9 0.15 11.5 3.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin CAP_N PF01213.14 ETO27386.1 - 0.61 9.3 8.2 0.09 12.0 2.8 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Inhibitor_I71 PF12628.2 ETO27388.1 - 3.6 7.2 6.0 6.1 6.4 2.9 2.0 1 1 1 2 2 2 0 Falstatin, cysteine peptidase inhibitor tRNA-synt_1e PF01406.14 ETO27389.1 - 0.087 11.9 2.1 0.095 11.7 1.5 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain NPR3 PF03666.8 ETO27389.1 - 1.7 7.0 8.6 1.9 6.9 6.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Menin PF05053.8 ETO27389.1 - 2.4 6.2 6.8 2.5 6.1 4.7 1.1 1 0 0 1 1 1 0 Menin Piwi PF02171.12 ETO27390.1 - 2.8e-11 42.9 0.0 1.4e-10 40.6 0.0 1.9 1 1 0 1 1 1 1 Piwi domain WD40 PF00400.27 ETO27392.1 - 2.8e-61 201.3 20.4 4.8e-12 45.2 1.3 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO27392.1 - 1.8e-12 46.1 7.2 0.11 10.6 0.0 6.1 1 1 3 6 6 6 6 Nucleoporin Nup120/160 DUF525 PF04379.9 ETO27392.1 - 3.1 7.8 6.4 0.26 11.2 0.4 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF525) Kelch_4 PF13418.1 ETO27393.1 - 0.00016 21.3 0.6 0.4 10.4 0.1 3.8 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO27393.1 - 0.001 18.5 3.9 0.015 14.8 0.4 3.6 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 ETO27393.1 - 0.0022 17.9 0.1 2.3 8.2 0.1 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO27393.1 - 0.0057 16.3 1.2 0.29 10.9 0.0 3.7 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 ETO27393.1 - 0.01 15.9 0.5 0.09 12.9 0.0 2.7 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO27393.1 - 0.026 14.7 3.7 0.8 9.9 0.2 3.8 3 1 1 4 4 4 0 Kelch motif RNA_lig_T4_1 PF09511.5 ETO27393.1 - 0.036 13.5 0.9 0.064 12.7 0.2 1.7 2 0 0 2 2 2 0 RNA ligase Tubulin PF00091.20 ETO27394.1 - 4.1e-59 200.0 0.1 6e-59 199.4 0.1 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO27394.1 - 9.4e-35 119.3 0.1 1.6e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Gly_kinase PF02595.10 ETO27394.1 - 0.0049 15.6 0.0 0.0071 15.0 0.0 1.1 1 0 0 1 1 1 1 Glycerate kinase family HHH_8 PF14716.1 ETO27395.1 - 7.1e-16 58.1 2.5 8.8e-16 57.8 0.4 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 ETO27395.1 - 2.6e-14 52.4 0.0 7e-14 51.1 0.0 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda WWE PF02825.15 ETO27395.1 - 9e-08 31.4 0.2 2.8e-07 29.8 0.1 1.9 1 0 0 1 1 1 1 WWE domain DNA_pol_B_palm PF14792.1 ETO27395.1 - 3.9e-07 30.1 0.1 1.3e-06 28.4 0.0 1.9 1 0 0 1 1 1 1 DNA polymerase beta palm HHH PF00633.18 ETO27395.1 - 4.3e-05 22.9 2.6 0.027 14.1 0.2 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_5 PF14520.1 ETO27395.1 - 0.00046 20.3 0.4 0.5 10.5 0.0 2.6 1 1 1 2 2 2 2 Helix-hairpin-helix domain IMS_HHH PF11798.3 ETO27395.1 - 0.0014 18.5 0.1 0.34 11.0 0.0 3.2 2 1 1 3 3 3 1 IMS family HHH motif DUF3068 PF11271.3 ETO27395.1 - 0.0035 16.4 1.0 0.0063 15.6 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3068) DUF1662 PF07878.6 ETO27396.1 - 0.03 14.0 0.3 0.068 12.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1662) ATP-synt_8 PF00895.15 ETO27396.1 - 0.89 9.8 0.0 0.89 9.8 0.0 3.9 2 1 1 3 3 3 0 ATP synthase protein 8 tRNA-synt_1g PF09334.6 ETO27397.1 - 1.3e-76 257.7 3.2 5e-75 252.5 2.2 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 ETO27397.1 - 1.8e-14 52.7 4.7 1.8e-11 42.8 0.8 3.7 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 ETO27397.1 - 1e-08 34.7 2.1 1.4e-08 34.2 1.5 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Ion_trans_2 PF07885.11 ETO27398.1 - 2.7e-19 68.6 19.0 6.7e-13 48.1 3.3 2.9 3 0 0 3 3 3 2 Ion channel EF-hand_1 PF00036.27 ETO27398.1 - 4.3e-10 38.1 1.5 0.00031 19.8 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 ETO27398.1 - 1.1e-08 34.2 0.9 0.0014 18.3 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 ETO27398.1 - 1.1e-08 34.0 4.3 0.00012 21.2 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 ETO27398.1 - 2.8e-05 23.6 0.4 0.2 11.3 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.1 ETO27398.1 - 6.8e-05 22.9 1.6 6.8e-05 22.9 1.1 3.0 2 1 1 3 3 3 2 EF-hand domain pair DUF1682 PF07946.9 ETO27398.1 - 0.00057 18.8 4.2 0.0013 17.6 2.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) ATP-synt_S1 PF05827.7 ETO27398.1 - 0.013 14.8 0.7 0.023 13.9 0.5 1.3 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) Atrophin-1 PF03154.10 ETO27398.1 - 0.014 13.5 2.8 0.02 13.0 1.9 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF1510 PF07423.6 ETO27398.1 - 0.016 14.5 7.7 0.037 13.4 5.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) OAD_gamma PF04277.8 ETO27398.1 - 0.14 12.5 1.7 0.47 10.8 1.2 2.0 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Bap31 PF05529.7 ETO27398.1 - 0.16 11.4 5.1 0.4 10.1 3.5 1.7 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF106 PF01956.11 ETO27398.1 - 3.3 7.2 5.6 1.1 8.8 0.1 2.8 3 0 0 3 3 3 0 Integral membrane protein DUF106 Ribosomal_S17e PF00833.13 ETO27398.1 - 3.8 7.2 9.8 0.093 12.4 1.2 2.4 3 1 1 4 4 4 0 Ribosomal S17 Peptidase_M17 PF00883.16 ETO27399.1 - 1.6e-87 293.2 1.9 8.6e-68 228.5 0.0 2.4 2 1 0 2 2 2 2 Cytosol aminopeptidase family, catalytic domain C6 PF01681.12 ETO27400.1 - 1.2 9.2 10.4 2.5 8.2 7.2 1.5 1 0 0 1 1 1 0 C6 domain Kelch_6 PF13964.1 ETO27401.1 - 2.2e-08 33.8 3.9 0.0012 18.9 0.1 4.0 2 2 2 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO27401.1 - 3.4e-06 26.5 1.0 0.00012 21.5 0.1 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 ETO27401.1 - 2e-05 24.6 0.0 0.0023 18.0 0.0 3.3 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO27401.1 - 2.7e-05 23.7 2.6 0.0027 17.4 0.2 3.0 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.1 ETO27401.1 - 0.00049 19.9 0.9 0.014 15.3 0.1 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETO27401.1 - 0.0027 17.4 0.0 0.022 14.5 0.0 2.5 2 0 0 2 2 2 1 Galactose oxidase, central domain Cylicin_N PF15241.1 ETO27401.1 - 0.039 13.8 0.2 0.081 12.8 0.1 1.4 1 0 0 1 1 1 0 Cylicin N-terminus KH_1 PF00013.24 ETO27402.1 - 1.6e-38 130.1 10.2 7.8e-15 54.2 1.4 3.4 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 ETO27402.1 - 3.9e-24 83.8 15.0 2.3e-10 39.8 1.3 3.5 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 ETO27402.1 - 5.4e-13 48.3 5.0 0.0015 18.1 0.0 4.4 5 0 0 5 5 5 3 KH domain KH_2 PF07650.12 ETO27402.1 - 4e-11 42.3 6.5 0.0035 16.8 0.1 3.6 3 0 0 3 3 3 3 KH domain Pox_D5 PF03288.11 ETO27403.1 - 0.21 11.8 1.3 0.46 10.7 0.9 1.7 1 0 0 1 1 1 0 Poxvirus D5 protein-like Mo25 PF08569.6 ETO27404.1 - 1.5e-17 63.6 1.1 1.6e-17 63.5 0.7 1.0 1 0 0 1 1 1 1 Mo25-like tRNA_Me_trans PF03054.11 ETO27404.1 - 0.019 13.5 0.0 0.024 13.2 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase MutL_C PF08676.6 ETO27404.1 - 0.079 12.5 0.2 0.16 11.5 0.1 1.6 1 1 0 1 1 1 0 MutL C terminal dimerisation domain PspA_IM30 PF04012.7 ETO27405.1 - 0.0017 17.7 11.5 0.0017 17.7 8.0 2.5 2 1 0 2 2 2 1 PspA/IM30 family Bacillus_HBL PF05791.6 ETO27405.1 - 0.0053 16.1 5.7 0.0053 16.1 3.9 3.0 1 1 2 3 3 3 2 Bacillus haemolytic enterotoxin (HBL) ING PF12998.2 ETO27405.1 - 0.014 15.6 2.7 0.014 15.6 1.8 3.5 2 2 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Sec8_exocyst PF04048.9 ETO27405.1 - 0.027 14.1 20.6 0.61 9.7 6.6 3.4 2 2 2 4 4 4 0 Sec8 exocyst complex component specific domain Tropomyosin_1 PF12718.2 ETO27405.1 - 0.073 12.9 35.6 0.37 10.6 5.2 3.2 2 1 1 3 3 3 0 Tropomyosin like IncA PF04156.9 ETO27405.1 - 0.23 11.0 36.6 0.95 9.0 13.5 2.4 1 1 1 2 2 2 0 IncA protein FUSC PF04632.7 ETO27405.1 - 0.5 8.7 2.8 0.59 8.4 1.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fez1 PF06818.10 ETO27405.1 - 0.92 9.4 26.9 1.3 9.0 1.3 3.1 2 1 0 2 2 2 0 Fez1 Filament PF00038.16 ETO27405.1 - 1 8.7 32.3 0.073 12.5 3.0 3.1 1 1 1 3 3 3 0 Intermediate filament protein Vicilin_N PF04702.7 ETO27405.1 - 1.3 8.6 24.6 0.011 15.3 4.5 2.1 1 1 1 2 2 2 0 Vicilin N terminal region Fib_alpha PF08702.5 ETO27405.1 - 3.1 7.9 23.2 2.8 8.0 6.8 3.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.3 ETO27405.1 - 5.1 4.2 32.2 0.13 9.5 11.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) BRE1 PF08647.6 ETO27405.1 - 6.7 6.7 34.2 0.078 12.9 4.5 4.2 3 1 0 4 4 4 0 BRE1 E3 ubiquitin ligase Lebercilin PF15619.1 ETO27405.1 - 7.3 5.9 36.9 1.8 7.9 2.3 3.2 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Matrilin_ccoil PF10393.4 ETO27405.1 - 9.9 5.6 16.0 0.59 9.5 0.5 4.4 3 1 1 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin PCI PF01399.22 ETO27406.1 - 0.018 15.3 0.1 0.054 13.8 0.0 1.6 2 0 0 2 2 2 0 PCI domain TPR_12 PF13424.1 ETO27407.1 - 0.031 14.1 0.1 22 5.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat PCI_Csn8 PF10075.4 ETO27407.1 - 0.045 13.5 0.1 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 Apc3 PF12895.2 ETO27407.1 - 0.068 13.3 6.6 0.72 10.0 0.0 3.8 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 ETO27407.1 - 0.074 12.9 3.9 31 4.8 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETO27407.1 - 0.15 12.4 0.0 5.6 7.3 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2756 PF10956.3 ETO27408.1 - 0.047 13.9 2.7 0.16 12.2 1.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) CAML PF14963.1 ETO27408.1 - 4.8 6.4 10.0 3.8 6.8 5.5 1.8 1 1 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand zf-CCCH PF00642.19 ETO27410.1 - 3.3e-16 58.5 40.2 0.00013 21.5 2.2 5.3 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 ETO27410.1 - 0.00041 20.2 44.9 0.13 12.2 2.7 6.2 5 1 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type RloB PF13707.1 ETO27412.1 - 0.13 11.8 1.8 0.21 11.2 1.2 1.2 1 0 0 1 1 1 0 RloB-like protein DivIC PF04977.10 ETO27412.1 - 0.14 11.6 0.8 3.5 7.1 0.0 3.1 3 0 0 3 3 3 0 Septum formation initiator Abhydrolase_5 PF12695.2 ETO27413.1 - 7.8e-11 41.9 0.0 1.5e-09 37.7 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETO27413.1 - 9.1e-11 42.0 0.0 1.5e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETO27413.1 - 0.00013 21.7 0.0 0.00031 20.5 0.0 1.6 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 ETO27413.1 - 0.00074 19.1 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 ETO27413.1 - 0.098 12.1 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 ETO27413.1 - 0.12 11.7 0.0 0.3 10.4 0.0 1.6 2 0 0 2 2 2 0 Putative esterase PYST-C1 PF09690.5 ETO27414.1 - 0.042 13.4 0.9 0.12 12.0 0.6 1.7 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) NCD1 PF04904.8 ETO27414.1 - 0.053 13.2 0.3 0.11 12.2 0.2 1.5 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) RVT_1 PF00078.22 ETO27415.1 - 5.6e-30 104.2 1.3 1.8e-29 102.6 0.9 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-Di19 PF05605.7 ETO27415.1 - 0.72 10.0 3.9 0.88 9.7 0.3 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 ETO27415.1 - 9.5 6.8 7.9 0.41 11.0 0.1 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type AF2331-like PF14556.1 ETO27416.1 - 0.14 12.5 0.3 0.14 12.5 0.2 1.9 2 0 0 2 2 2 0 AF2331-like DUF912 PF06024.7 ETO27416.1 - 5.3 7.1 9.4 0.61 10.1 0.1 2.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) NACHT PF05729.7 ETO27417.1 - 1e-17 64.2 0.0 4.2e-17 62.3 0.0 2.2 1 0 0 1 1 1 1 NACHT domain HEAT_2 PF13646.1 ETO27417.1 - 7.9e-07 29.2 0.0 0.0066 16.6 0.0 3.2 2 1 1 3 3 3 3 HEAT repeats HEAT PF02985.17 ETO27417.1 - 3.3e-06 26.6 0.9 0.058 13.5 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat AAA_16 PF13191.1 ETO27417.1 - 2e-05 24.6 0.0 0.00072 19.5 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 ETO27417.1 - 0.024 14.8 0.1 0.2 11.8 0.0 2.7 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.12 ETO27417.1 - 0.048 13.4 10.5 2.4 7.9 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function DUF87 AAA_18 PF13238.1 ETO27417.1 - 0.39 11.0 0.0 0.39 11.0 0.0 3.8 4 1 0 4 4 4 0 AAA domain DUF1108 PF06531.6 ETO27418.1 - 0.051 13.7 0.1 0.1 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1108) DUF4325 PF14213.1 ETO27418.1 - 0.053 13.1 0.1 0.093 12.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4325) DUF2611 PF11022.3 ETO27418.1 - 0.19 11.8 0.9 0.37 10.9 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2611) Pkinase PF00069.20 ETO27419.1 - 0.00016 20.9 0.0 0.00026 20.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain G-alpha PF00503.15 ETO27420.1 - 8.5e-60 202.4 10.7 1e-59 202.2 7.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO27420.1 - 1.5e-07 30.7 0.9 3.4e-07 29.6 0.6 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETO27420.1 - 1.6e-06 27.4 1.7 1.9e-06 27.1 0.5 1.7 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_33 PF13671.1 ETO27420.1 - 0.13 12.1 0.2 0.52 10.1 0.0 2.0 2 1 0 2 2 2 0 AAA domain CDC45 PF02724.9 ETO27421.1 - 0.21 9.6 11.4 0.29 9.1 7.9 1.2 1 0 0 1 1 1 0 CDC45-like protein HutP PF09021.6 ETO27421.1 - 0.27 11.4 1.9 0.4 10.8 1.3 1.3 1 0 0 1 1 1 0 HutP DUF3827 PF12877.2 ETO27421.1 - 0.6 8.1 12.1 0.67 7.9 8.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Zip PF02535.17 ETO27421.1 - 0.78 8.6 5.9 1 8.2 4.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Paramyxo_ncap PF00973.14 ETO27421.1 - 1.9 7.0 7.8 2 7.0 5.4 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Ax_dynein_light PF10211.4 ETO27421.1 - 3.8 7.3 8.9 5.5 6.7 6.2 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain Neur_chan_memb PF02932.11 ETO27421.1 - 5.7 6.7 8.8 6.4 6.5 6.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Otopetrin PF03189.8 ETO27421.1 - 5.9 5.7 6.6 7 5.5 4.6 1.1 1 0 0 1 1 1 0 Otopetrin DNA_pol_viral_N PF00242.12 ETO27421.1 - 8.9 5.2 17.1 9.4 5.1 11.8 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Menin PF05053.8 ETO27421.1 - 9.6 4.2 10.6 10 4.1 7.3 1.1 1 0 0 1 1 1 0 Menin WD40 PF00400.27 ETO27422.1 - 6.8e-07 28.9 1.2 0.00095 18.9 0.4 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat CDC45 PF02724.9 ETO27422.1 - 0.077 11.0 20.3 0.28 9.1 3.2 2.1 2 0 0 2 2 2 0 CDC45-like protein GAGA_bind PF06217.7 ETO27423.1 - 6.5 6.6 14.3 8.3 6.2 9.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family EF-hand_7 PF13499.1 ETO27424.1 - 0.018 15.1 2.3 0.67 10.1 0.0 2.7 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.27 ETO27424.1 - 0.02 14.1 1.4 0.035 13.4 0.1 2.2 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.1 ETO27424.1 - 0.073 12.7 0.3 0.42 10.2 0.0 2.3 1 1 2 3 3 3 0 EF-hand domain pair P5-ATPase PF12409.3 ETO27424.1 - 0.19 11.5 0.8 0.25 11.1 0.5 1.3 1 0 0 1 1 1 0 P5-type ATPase cation transporter GCC2_GCC3 PF07699.8 ETO27425.1 - 0.027 14.0 0.5 0.027 14.0 0.4 2.7 2 0 0 2 2 2 0 GCC2 and GCC3 C1_2 PF03107.11 ETO27425.1 - 0.3 11.2 3.4 0.18 11.9 0.2 2.3 2 0 0 2 2 2 0 C1 domain Med4 PF10018.4 ETO27427.1 - 7.9e-06 25.3 2.8 7.9e-06 25.3 1.9 2.3 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 Latarcin PF10279.4 ETO27427.1 - 0.047 13.8 0.0 0.047 13.8 0.0 1.9 2 1 0 2 2 2 0 Latarcin precursor DNA_pack_N PF02500.10 ETO27427.1 - 3.3 7.1 6.3 0.32 10.5 0.7 1.8 2 0 0 2 2 2 0 Probable DNA packing protein, N-terminus Fib_alpha PF08702.5 ETO27427.1 - 5.2 7.1 11.6 0.16 12.0 1.0 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family WD40 PF00400.27 ETO27428.1 - 1e-60 199.5 22.5 1.2e-11 44.0 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO27428.1 - 9.8e-07 27.2 3.5 0.018 13.2 0.1 3.6 1 1 1 3 3 3 3 Nucleoporin Nup120/160 DUF1258 PF06869.7 ETO27428.1 - 0.00093 18.3 1.2 0.13 11.3 0.1 3.0 2 2 2 4 4 4 1 Protein of unknown function (DUF1258) PQQ_2 PF13360.1 ETO27428.1 - 0.001 18.5 0.5 0.014 14.8 0.3 2.0 1 1 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO27428.1 - 0.003 15.8 1.5 0.024 12.9 0.2 2.2 1 1 1 2 2 2 1 Cytochrome D1 heme domain NHL PF01436.16 ETO27428.1 - 0.034 14.1 0.2 0.85 9.6 0.0 3.0 3 0 0 3 3 3 0 NHL repeat Nucleoporin_N PF08801.6 ETO27428.1 - 0.086 11.5 8.9 0.18 10.5 0.1 3.0 1 1 2 3 3 3 0 Nup133 N terminal like Hira PF07569.6 ETO27428.1 - 0.1 11.7 0.3 2 7.5 0.0 2.6 2 1 1 3 3 3 0 TUP1-like enhancer of split PD40 PF07676.7 ETO27428.1 - 0.43 10.3 4.5 34 4.2 0.1 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF1312 PF07009.6 ETO27429.1 - 1.3 8.8 4.3 0.66 9.7 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1312) CBFB_NFYA PF02045.10 ETO27431.1 - 1.3e-11 44.8 7.4 2.7e-11 43.8 5.1 1.6 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B CCT PF06203.9 ETO27431.1 - 0.00037 20.0 0.5 0.0007 19.1 0.4 1.4 1 0 0 1 1 1 1 CCT motif Lin-8 PF03353.10 ETO27432.1 - 0.33 10.2 10.2 0.38 9.9 7.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist LPP20 PF02169.11 ETO27436.1 - 0.13 12.3 6.9 1.4 9.0 2.4 2.2 2 0 0 2 2 2 0 LPP20 lipoprotein ANT PF03374.9 ETO27436.1 - 0.17 11.9 0.2 0.17 11.9 0.1 1.5 2 0 0 2 2 2 0 Phage antirepressor protein KilAC domain Macoilin PF09726.4 ETO27436.1 - 1.7 6.8 13.2 2 6.6 9.2 1.0 1 0 0 1 1 1 0 Transmembrane protein UQ_con PF00179.21 ETO27438.1 - 3.8e-43 146.2 0.5 8.3e-42 141.9 0.0 2.3 1 1 1 2 2 2 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 ETO27438.1 - 2.9e-06 27.0 0.0 5.6e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 ETO27438.1 - 0.025 14.2 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 UEV domain RWD PF05773.17 ETO27438.1 - 0.052 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 RWD domain Asp_Arg_Hydrox PF05118.10 ETO27439.1 - 0.011 15.6 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 0 Aspartyl/Asparaginyl beta-hydroxylase DUF1057 PF06342.7 ETO27439.1 - 0.14 10.9 0.3 0.18 10.6 0.2 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Ras PF00071.17 ETO27440.1 - 3.2e-29 101.4 1.6 6.2e-29 100.4 0.2 1.9 1 1 1 2 2 2 1 Ras family Miro PF08477.8 ETO27440.1 - 4.9e-13 49.6 0.1 2.1e-12 47.5 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO27440.1 - 0.00027 20.2 0.0 0.00048 19.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO27440.1 - 0.0011 18.4 0.0 0.0042 16.5 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 ETO27440.1 - 0.029 14.3 0.0 0.073 13.0 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase Acylphosphatase PF00708.13 ETO27440.1 - 0.1 12.7 0.4 0.24 11.5 0.3 1.6 1 0 0 1 1 1 0 Acylphosphatase Ion_trans PF00520.26 ETO27440.1 - 1.7 7.8 9.2 0.16 11.1 1.5 2.2 2 0 0 2 2 2 0 Ion transport protein DUF1620 PF07774.8 ETO27442.1 - 0.032 13.4 1.5 0.058 12.6 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1620) PA26 PF04636.8 ETO27442.1 - 0.11 11.1 7.4 0.16 10.6 5.1 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Kelch_6 PF13964.1 ETO27444.1 - 2.2e-05 24.4 3.5 0.088 13.0 0.1 4.7 5 1 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO27444.1 - 0.0002 21.0 1.4 0.026 14.3 0.1 3.9 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO27444.1 - 0.0012 18.3 1.2 4.2 7.0 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO27444.1 - 0.0015 18.5 0.0 0.33 11.1 0.0 3.1 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO27444.1 - 0.021 14.7 0.2 33 4.5 0.0 4.2 4 0 0 4 4 4 0 Kelch motif MinC_C PF03775.11 ETO27445.1 - 0.13 11.9 0.4 0.26 10.9 0.0 1.7 2 0 0 2 2 2 0 Septum formation inhibitor MinC, C-terminal domain WD40 PF00400.27 ETO27446.1 - 8.8e-59 193.4 26.8 5.8e-10 38.6 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO27446.1 - 3.3e-11 42.0 13.2 0.0014 16.9 0.8 6.0 2 2 3 6 6 6 5 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO27446.1 - 3.9e-06 27.1 2.3 3.9e-06 27.1 1.6 2.7 2 0 0 2 2 2 1 TRAF-type zinc finger DUF1900 PF08954.6 ETO27446.1 - 0.042 13.3 0.2 2.8 7.4 0.0 3.7 5 0 0 5 5 5 0 Domain of unknown function (DUF1900) LMBR1 PF04791.11 ETO27446.1 - 3.7 6.0 7.1 5.1 5.5 4.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein WD40 PF00400.27 ETO27447.1 - 3.6e-56 185.1 24.5 3.7e-11 42.4 0.9 7.4 6 1 0 6 6 6 5 WD domain, G-beta repeat zf-TRAF PF02176.13 ETO27447.1 - 0.00052 20.3 3.2 0.00052 20.3 2.2 2.4 2 0 0 2 2 2 1 TRAF-type zinc finger SH2 PF00017.19 ETO27447.1 - 0.013 15.2 0.5 0.24 11.2 0.0 3.5 2 1 0 2 2 2 0 SH2 domain PilM PF07419.7 ETO27447.1 - 0.027 13.9 0.0 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 PilM zf-C3HC4_2 PF13923.1 ETO27447.1 - 5.2 7.1 8.2 0.4 10.7 0.7 2.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF3279 PF11682.3 ETO27448.1 - 0.028 14.0 1.1 0.055 13.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3279) Lipoprotein_10 PF03202.8 ETO27448.1 - 5.2 7.0 10.1 0.58 10.1 2.2 2.2 2 0 0 2 2 2 0 Putative mycoplasma lipoprotein, C-terminal region DUF310 PF03750.8 ETO27449.1 - 0.31 11.2 11.9 0.41 10.8 0.4 4.0 2 2 1 3 3 3 0 Protein of unknown function (DUF310) Laminin_II PF06009.7 ETO27449.1 - 0.31 10.8 20.6 0.1 12.3 2.2 4.6 3 2 2 5 5 5 0 Laminin Domain II DUF4349 PF14257.1 ETO27449.1 - 0.92 8.6 7.9 1.2 8.3 2.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) NTP_transf_2 PF01909.18 ETO27450.1 - 8.2e-06 26.0 0.0 2.2e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 Nucleotidyltransferase domain PAP_central PF04928.12 ETO27450.1 - 0.00031 19.6 0.0 0.00038 19.3 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain DUF3439 PF11921.3 ETO27451.1 - 0.014 15.1 2.4 0.037 13.7 1.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) WD40 PF00400.27 ETO27452.1 - 3.1e-44 147.3 9.3 7.9e-12 44.5 0.0 4.7 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO27452.1 - 3.5e-09 35.3 2.0 0.0012 17.1 0.0 3.8 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO27452.1 - 0.054 12.2 2.2 0.17 10.6 0.9 2.3 1 1 1 2 2 2 0 Nup133 N terminal like Oxysterol_BP PF01237.13 ETO27452.1 - 0.24 9.8 1.5 3 6.2 0.0 2.1 2 0 0 2 2 2 0 Oxysterol-binding protein Pkinase PF00069.20 ETO27453.1 - 3.8e-13 49.1 0.0 6.1e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO27453.1 - 0.028 13.4 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase MIP-T3 PF10243.4 ETO27454.1 - 0.0071 14.8 38.0 0.0089 14.5 26.3 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 TFIIF_alpha PF05793.7 ETO27454.1 - 0.7 8.1 35.5 0.79 8.0 24.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Phage_Gp23 PF10669.4 ETO27454.1 - 1.2 9.2 12.6 2.1 8.4 8.7 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) F-protein PF00469.15 ETO27454.1 - 4.4 6.6 18.0 6.1 6.1 7.8 2.1 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef TFIIF_alpha PF05793.7 ETO27455.1 - 0.011 14.1 11.3 0.012 14.0 7.9 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.7 ETO27455.1 - 0.34 10.1 11.3 0.36 10.0 7.8 1.1 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 ETO27455.1 - 0.35 9.3 8.3 0.4 9.1 5.8 1.2 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 ETO27455.1 - 0.4 8.6 11.1 0.43 8.5 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2201_N PF13203.1 ETO27455.1 - 0.45 9.6 2.7 0.58 9.2 1.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain YL1 PF05764.8 ETO27455.1 - 0.73 9.4 7.0 0.8 9.2 4.9 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Osteopontin PF00865.13 ETO27455.1 - 2.7 7.1 21.3 3.5 6.7 14.7 1.3 1 0 0 1 1 1 0 Osteopontin HSP90 PF00183.13 ETO27455.1 - 4.4 5.5 8.8 5.2 5.3 6.1 1.0 1 0 0 1 1 1 0 Hsp90 protein Nop14 PF04147.7 ETO27455.1 - 4.7 4.9 18.5 5.7 4.7 12.8 1.0 1 0 0 1 1 1 0 Nop14-like family PUF PF00806.14 ETO27456.1 - 1.2e-21 74.8 4.5 5.2e-05 22.5 0.1 4.5 4 0 0 4 4 4 4 Pumilio-family RNA binding repeat HD_assoc PF13286.1 ETO27457.1 - 0.097 12.9 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Phosphohydrolase-associated domain PH PF00169.24 ETO27458.1 - 0.00014 21.9 0.0 0.0006 19.9 0.0 2.0 1 0 0 1 1 1 1 PH domain Lectin_N PF03954.9 ETO27458.1 - 0.13 11.7 0.5 0.37 10.1 0.1 2.0 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain PhyH PF05721.8 ETO27459.1 - 2e-09 37.8 0.0 3.5e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Ni_hydr_CYTB PF01292.15 ETO27460.1 - 0.016 14.6 2.5 0.019 14.3 1.7 1.1 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 ATP-synt_8 PF00895.15 ETO27460.1 - 2 8.6 10.1 6 7.1 1.3 3.1 2 1 1 3 3 3 0 ATP synthase protein 8 HECT PF00632.20 ETO27461.1 - 5.6e-56 189.9 0.0 1e-55 189.1 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Laminin_G_3 PF13385.1 ETO27461.1 - 1.5e-13 51.2 0.0 3.5e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.19 ETO27461.1 - 3.5e-06 27.0 0.0 8.1e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.18 ETO27461.1 - 0.016 15.1 0.1 0.038 14.0 0.1 1.5 1 0 0 1 1 1 0 Laminin G domain Tetraspannin PF00335.15 ETO27462.1 - 4.8e-23 81.5 17.8 7.5e-23 80.9 12.4 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF843 PF05814.6 ETO27462.1 - 0.042 13.6 0.6 0.042 13.6 0.4 2.4 3 0 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) DUF502 PF04367.8 ETO27463.1 - 0.093 12.5 0.8 0.15 11.8 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF502) RHD PF00554.17 ETO27464.1 - 0.018 14.8 1.3 0.27 10.9 0.0 2.1 2 0 0 2 2 2 0 Rel homology domain (RHD) UPF0203 PF05254.7 ETO27465.1 - 0.43 10.4 3.8 21 5.0 0.1 3.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0203) PH PF00169.24 ETO27466.1 - 5e-06 26.6 0.4 2e-05 24.7 0.1 2.2 2 0 0 2 2 2 1 PH domain EF-hand_7 PF13499.1 ETO27466.1 - 0.0032 17.5 4.6 0.074 13.1 1.2 3.0 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO27466.1 - 0.0063 16.3 3.9 6.1 7.0 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 ETO27466.1 - 0.011 14.9 10.5 0.2 11.0 0.9 3.7 4 0 0 4 4 4 0 EF hand EF-hand_8 PF13833.1 ETO27466.1 - 0.014 15.0 1.0 0.06 12.9 0.4 2.3 2 0 0 2 2 2 0 EF-hand domain pair Macoilin PF09726.4 ETO27466.1 - 0.099 10.9 15.3 0.17 10.1 10.6 1.4 1 0 0 1 1 1 0 Transmembrane protein Menin PF05053.8 ETO27466.1 - 1.5 6.9 7.2 2.7 6.0 5.0 1.4 1 0 0 1 1 1 0 Menin CN_hydrolase PF00795.17 ETO27467.1 - 1.1e-12 47.6 0.0 1.4e-12 47.3 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NPCC PF08058.6 ETO27468.1 - 1.7 8.4 6.0 8.2 6.2 0.5 2.2 2 0 0 2 2 2 0 Nuclear pore complex component EF-hand_6 PF13405.1 ETO27470.1 - 0.0002 20.9 0.3 0.03 14.2 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.1 ETO27470.1 - 0.001 19.1 0.7 0.0055 16.8 0.1 2.3 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO27470.1 - 0.0086 15.3 0.0 1.2 8.5 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 ETO27470.1 - 0.065 12.8 7.1 0.083 12.5 0.6 3.5 3 1 0 3 3 3 0 EF-hand domain pair O-FucT PF10250.4 ETO27471.1 - 4.8e-10 39.0 1.4 1.4e-09 37.5 1.0 1.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Pkinase PF00069.20 ETO27472.1 - 1.2e-34 119.6 3.0 1.4e-34 119.4 2.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO27472.1 - 9.7e-22 77.2 0.7 1.1e-21 77.1 0.5 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETO27472.1 - 0.11 12.1 0.0 0.71 9.5 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1179 PF06678.6 ETO27473.1 - 0.041 14.1 0.0 0.046 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) DUF1180 PF06679.7 ETO27473.1 - 0.08 12.8 0.1 0.11 12.3 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) PT PF04886.7 ETO27474.1 - 1.5e-26 91.3 165.7 7.5e-08 31.5 12.0 9.5 3 3 3 6 6 6 2 PT repeat peroxidase PF00141.18 ETO27475.1 - 4.8e-36 124.3 0.0 6.2e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase ATP13 PF12921.2 ETO27475.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ATPase expression FAA_hydrolase PF01557.13 ETO27476.1 - 5.9e-07 29.1 0.0 6.7e-07 28.9 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family WW PF00397.21 ETO27477.1 - 1.4e-07 31.2 1.5 1.4e-07 31.2 1.0 2.0 2 0 0 2 2 2 1 WW domain FF PF01846.14 ETO27478.1 - 1.3e-11 44.2 2.2 2.1e-11 43.6 0.3 2.2 2 0 0 2 2 2 1 FF domain DUF913 PF06025.7 ETO27478.1 - 3.6 6.2 7.8 0.39 9.4 2.3 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Mucin PF01456.12 ETO27479.1 - 1.8 8.3 18.5 4.4 7.0 12.8 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein Bac_rhamnosid PF05592.6 ETO27481.1 - 1.1e-31 109.6 0.1 2.1e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Pkinase PF00069.20 ETO27482.1 - 2.9e-13 49.5 0.2 1.3e-11 44.1 0.0 2.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO27482.1 - 0.012 14.6 0.0 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase Gly-zipper_Omp PF13488.1 ETO27483.1 - 0.02 14.5 0.3 0.042 13.4 0.2 1.5 1 0 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.1 ETO27483.1 - 0.082 12.4 0.3 0.14 11.7 0.2 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.10 ETO27483.1 - 0.14 11.8 1.9 0.78 9.4 1.3 2.1 1 1 0 1 1 1 0 Glycine zipper 2TM domain DUF456 PF04306.8 ETO27483.1 - 5.9 6.9 11.0 5.3 7.0 3.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF456) AMP-binding_C_2 PF14535.1 ETO27485.1 - 0.037 14.0 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain TRIQK PF15168.1 ETO27485.1 - 0.21 11.5 1.1 0.36 10.7 0.2 1.7 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family Scaffolding_pro PF11418.3 ETO27487.1 - 0.0014 18.9 4.1 0.009 16.3 0.2 3.3 3 0 0 3 3 3 1 Phi29 scaffolding protein DUF4360 PF14273.1 ETO27489.1 - 4.3 6.9 11.6 4.2 6.9 7.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4360) HALZ PF02183.13 ETO27490.1 - 0.0034 17.0 4.1 0.0052 16.4 1.8 2.0 1 1 1 2 2 2 1 Homeobox associated leucine zipper HisG_C PF08029.6 ETO27490.1 - 0.021 14.7 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 HisG, C-terminal domain Cep57_CLD_2 PF14197.1 ETO27490.1 - 0.043 13.7 1.1 0.093 12.6 0.5 1.8 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 ADIP PF11559.3 ETO27490.1 - 0.12 12.2 5.5 1.7 8.5 0.1 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF440 PF04269.7 ETO27490.1 - 0.12 12.4 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF440 DUF3450 PF11932.3 ETO27490.1 - 0.14 11.4 3.6 0.11 11.8 1.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Tubulin_3 PF14881.1 ETO27490.1 - 0.2 11.0 1.1 0.35 10.3 0.8 1.5 1 1 0 1 1 1 0 Tubulin domain CENP-H PF05837.7 ETO27490.1 - 0.41 10.8 3.5 0.86 9.8 1.7 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) TraA PF05513.6 ETO27491.1 - 0.081 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 TraA Glyco_transf_8 PF01501.15 ETO27492.1 - 7.9e-08 31.9 0.0 1.1e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 UDP-g_GGTase PF06427.6 ETO27493.1 - 2.9e-24 85.5 0.3 3.1e-17 62.6 0.0 2.9 2 0 0 2 2 2 2 UDP-glucose:Glycoprotein Glucosyltransferase FAM70 PF14967.1 ETO27496.1 - 8.5 5.4 6.4 17 4.4 4.4 1.4 1 0 0 1 1 1 0 FAM70 protein DUF3916 PF13079.1 ETO27498.1 - 0.0076 15.9 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3916) CPSase_L_chain PF00289.17 ETO27499.1 - 0.057 13.5 0.0 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain PTH2 PF01981.11 ETO27500.1 - 3.1e-32 110.7 0.0 3.6e-32 110.4 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 TPR_11 PF13414.1 ETO27501.1 - 7.8e-21 73.5 7.2 1.9e-11 43.4 0.4 3.3 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETO27501.1 - 2.1e-12 46.0 12.3 2.2e-06 27.0 0.3 4.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO27501.1 - 1.2e-11 43.8 0.6 0.00069 19.6 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO27501.1 - 7.8e-11 41.7 4.4 8.2e-07 28.8 0.2 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO27501.1 - 1.4e-09 37.1 10.7 0.00012 21.7 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO27501.1 - 1.6e-09 38.2 0.0 2.6e-05 24.7 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO27501.1 - 2.8e-09 36.0 8.4 5.5e-06 25.7 0.2 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO27501.1 - 5.1e-08 33.1 0.5 0.00088 19.5 0.1 3.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO27501.1 - 1.7e-07 31.2 0.0 0.0013 19.1 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO27501.1 - 1.1e-05 25.5 1.3 0.088 13.3 0.0 4.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO27501.1 - 0.0029 17.2 1.7 0.44 10.4 0.0 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat Sel1 PF08238.7 ETO27501.1 - 0.0047 17.5 0.2 6.7 7.4 0.0 2.7 2 0 0 2 2 2 1 Sel1 repeat TPR_10 PF13374.1 ETO27501.1 - 0.0063 16.4 0.2 0.41 10.6 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO27501.1 - 0.012 15.6 4.1 0.1 12.7 1.0 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Wx5_PLAF3D7 PF09688.5 ETO27501.1 - 0.019 14.9 1.1 0.019 14.9 0.8 2.1 2 1 0 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) SHNi-TPR PF10516.4 ETO27501.1 - 0.024 13.8 0.5 3.7 6.8 0.0 3.3 3 1 0 3 3 3 0 SHNi-TPR MIT PF04212.13 ETO27501.1 - 0.054 13.3 1.3 17 5.4 0.0 3.1 2 2 1 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_9 PF13371.1 ETO27501.1 - 0.1 12.4 0.2 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4200 PF13863.1 ETO27501.1 - 0.11 12.4 2.1 0.28 11.1 1.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) RRM_1 PF00076.17 ETO27502.1 - 1.8e-13 49.9 0.5 2.5e-13 49.4 0.3 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO27502.1 - 8.2e-12 44.9 0.0 1.4e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO27502.1 - 0.0027 17.5 0.4 0.0054 16.5 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ICAP-1_inte_bdg PF10480.4 ETO27503.1 - 0.1 12.3 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 Beta-1 integrin binding protein SAPS PF04499.10 ETO27504.1 - 0.0015 17.2 7.7 0.0015 17.2 5.3 1.6 1 1 1 2 2 2 1 SIT4 phosphatase-associated protein Hid1 PF12722.2 ETO27504.1 - 0.052 11.2 2.4 0.05 11.2 1.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NUDIX_2 PF13869.1 ETO27504.1 - 0.14 11.4 2.4 4.1 6.6 0.1 2.5 1 1 1 2 2 2 0 Nucleotide hydrolase RR_TM4-6 PF06459.7 ETO27504.1 - 1.7 8.4 4.9 2.2 8.1 3.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BCL_N PF04714.8 ETO27505.1 - 0.11 12.0 0.1 0.29 10.7 0.1 1.7 1 0 0 1 1 1 0 BCL7, N-terminal conserver region EF-hand_1 PF00036.27 ETO27506.1 - 1.7e-14 51.8 11.9 1.3e-06 27.2 2.8 3.5 3 1 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 ETO27506.1 - 1.7e-13 50.5 2.9 1.7e-13 50.5 2.0 1.8 2 1 0 2 2 1 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO27506.1 - 2.8e-11 42.2 10.4 3.7e-06 26.3 0.0 4.2 2 1 3 5 5 5 2 EF-hand domain EF-hand_8 PF13833.1 ETO27506.1 - 2.7e-07 30.0 9.0 1.1e-06 28.0 4.0 2.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 ETO27506.1 - 3.3e-07 29.3 14.1 0.00036 19.7 0.1 4.3 3 1 1 4 4 4 2 EF hand EF-hand_4 PF12763.2 ETO27506.1 - 3.6e-05 23.4 0.3 5.6e-05 22.8 0.2 1.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 ETO27506.1 - 0.00027 20.7 0.1 0.00055 19.7 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain SPARC_Ca_bdg PF10591.4 ETO27506.1 - 0.0035 17.3 0.3 0.0049 16.8 0.2 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.8 ETO27506.1 - 0.0083 15.6 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 Caleosin related protein Filaggrin PF03516.8 ETO27506.1 - 0.033 14.6 0.3 0.057 13.8 0.2 1.3 1 0 0 1 1 1 0 Filaggrin TerB PF05099.8 ETO27506.1 - 0.048 13.3 0.1 0.2 11.4 0.0 1.8 1 1 1 2 2 2 0 Tellurite resistance protein TerB RNA_pol_Rpb1_5 PF04998.12 ETO27506.1 - 0.05 12.8 0.5 0.056 12.7 0.4 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 UBN_AB PF14075.1 ETO27506.1 - 0.36 10.4 2.7 5.7 6.5 2.3 2.0 2 0 0 2 2 2 0 Ubinuclein conserved middle domain EamA PF00892.15 ETO27507.1 - 0.0041 17.1 5.4 0.0078 16.2 0.5 2.1 2 0 0 2 2 2 1 EamA-like transporter family Fanconi_A PF03511.9 ETO27507.1 - 0.096 12.4 0.2 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 Fanconi anaemia group A protein DUF2628 PF10947.3 ETO27507.1 - 0.11 12.3 0.9 0.34 10.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) SprA-related PF12118.3 ETO27507.1 - 0.11 11.8 15.1 0.14 11.5 10.5 1.1 1 0 0 1 1 1 0 SprA-related family Trypan_PARP PF05887.6 ETO27507.1 - 1.8 8.3 5.9 3.3 7.5 4.1 1.4 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SR-25 PF10500.4 ETO27507.1 - 5.4 6.4 34.3 0.016 14.6 15.1 2.1 1 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4220 PF13968.1 ETO27507.1 - 6.2 5.8 6.0 8.3 5.3 4.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) ETRAMP PF09716.5 ETO27507.1 - 9.2 6.3 10.5 0.16 11.9 0.6 2.6 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) FNIP PF05725.7 ETO27508.1 - 0.0068 16.3 0.2 2 8.4 0.0 3.3 2 1 0 2 2 2 2 FNIP Repeat APO_RNA-bind PF05634.6 ETO27509.1 - 0.13 11.3 2.6 0.063 12.4 0.3 1.7 2 0 0 2 2 2 0 APO RNA-binding Ras PF00071.17 ETO27510.1 - 7.2e-21 74.2 0.1 3.3e-20 72.0 0.0 1.9 1 1 0 1 1 1 1 Ras family GTP_EFTU PF00009.22 ETO27510.1 - 0.016 14.6 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF2082 PF09855.4 ETO27510.1 - 0.066 13.0 0.5 0.13 12.1 0.3 1.5 1 1 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) PUB PF09409.5 ETO27511.1 - 3.5e-08 33.1 2.0 7.1e-08 32.1 0.1 2.3 2 0 0 2 2 2 1 PUB domain ABC2_membrane_3 PF12698.2 ETO27513.1 - 5.5e-21 74.9 15.8 8.5e-21 74.3 10.9 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.22 ETO27513.1 - 9.7e-20 71.2 0.0 2.7e-19 69.8 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_23 PF13476.1 ETO27513.1 - 0.01 16.1 0.1 0.018 15.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 ETO27513.1 - 0.014 14.9 1.1 0.03 13.8 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain Med4 PF10018.4 ETO27514.1 - 0.00036 20.0 3.2 0.00041 19.8 2.2 1.1 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 CDC45 PF02724.9 ETO27514.1 - 0.0007 17.7 0.9 0.00077 17.6 0.6 1.2 1 0 0 1 1 1 1 CDC45-like protein Pox_Ag35 PF03286.9 ETO27514.1 - 0.011 15.2 9.4 0.016 14.7 6.5 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein BLVR PF06375.6 ETO27514.1 - 0.013 15.2 10.2 0.02 14.7 7.1 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Peptidase_S49_N PF08496.5 ETO27514.1 - 0.014 15.1 3.6 0.023 14.5 2.5 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Nop14 PF04147.7 ETO27514.1 - 0.017 13.1 15.1 0.02 12.8 10.5 1.1 1 0 0 1 1 1 0 Nop14-like family DDHD PF02862.12 ETO27514.1 - 0.044 13.5 5.2 0.056 13.2 3.6 1.2 1 0 0 1 1 1 0 DDHD domain Fmp27_WPPW PF10359.4 ETO27514.1 - 0.047 12.0 7.7 0.067 11.6 5.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Zip PF02535.17 ETO27514.1 - 0.089 11.7 0.3 0.11 11.5 0.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1510 PF07423.6 ETO27514.1 - 0.1 11.9 15.2 0.14 11.4 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CobT PF06213.7 ETO27514.1 - 0.12 11.4 11.1 0.16 11.1 7.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RCC1_2 PF13540.1 ETO27514.1 - 0.17 11.5 1.4 0.26 10.9 0.1 2.0 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat Ycf1 PF05758.7 ETO27514.1 - 0.19 9.4 7.1 0.22 9.1 4.9 1.1 1 0 0 1 1 1 0 Ycf1 Tim54 PF11711.3 ETO27514.1 - 0.22 10.0 11.3 0.3 9.6 7.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Daxx PF03344.10 ETO27514.1 - 0.3 9.5 16.9 0.39 9.1 11.7 1.1 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 ETO27514.1 - 0.35 10.1 18.4 0.47 9.6 12.8 1.1 1 0 0 1 1 1 0 SDA1 PBP_sp32 PF07222.7 ETO27514.1 - 0.51 9.4 11.1 0.72 8.9 7.7 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CENP-B_dimeris PF09026.5 ETO27514.1 - 0.64 10.2 8.5 1.3 9.2 5.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DHHW PF14286.1 ETO27514.1 - 0.82 8.9 8.2 1.2 8.4 5.7 1.2 1 0 0 1 1 1 0 DHHW protein FLO_LFY PF01698.11 ETO27514.1 - 1.1 7.9 10.1 3.6 6.3 6.7 1.9 2 0 0 2 2 2 0 Floricaula / Leafy protein TRAP_alpha PF03896.11 ETO27514.1 - 1.4 7.8 9.4 2 7.3 6.5 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Vfa1 PF08432.5 ETO27514.1 - 1.5 8.8 14.6 2.2 8.2 10.1 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 BTV_NS2 PF04514.7 ETO27514.1 - 2.9 6.6 12.0 4 6.2 8.3 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 NOA36 PF06524.7 ETO27514.1 - 3.1 6.9 7.7 4 6.5 5.3 1.1 1 0 0 1 1 1 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.3 ETO27514.1 - 3.5 7.4 18.9 5.8 6.7 13.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Prog_receptor PF02161.10 ETO27514.1 - 4.6 5.9 7.3 5.8 5.6 5.1 1.1 1 0 0 1 1 1 0 Progesterone receptor Atrophin-1 PF03154.10 ETO27514.1 - 5.6 4.9 8.9 8 4.4 6.2 1.1 1 0 0 1 1 1 0 Atrophin-1 family ABC2_membrane_3 PF12698.2 ETO27515.1 - 4.3e-22 78.6 20.8 1.1e-21 77.2 14.4 1.7 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.22 ETO27515.1 - 8.2e-15 55.3 0.0 2.3e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 ABC transporter VanZ PF04892.7 ETO27516.1 - 0.092 12.7 0.8 0.13 12.2 0.5 1.3 1 0 0 1 1 1 0 VanZ like family Consortin_C PF15281.1 ETO27517.1 - 0.011 15.1 0.0 0.029 13.8 0.0 1.7 1 0 0 1 1 1 0 Consortin C-terminus Mcp5_PH PF12814.2 ETO27517.1 - 0.26 11.1 2.7 1.3 8.9 0.5 2.6 2 1 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology Methyltransf_12 PF08242.7 ETO27517.1 - 9.3 6.8 8.8 0.43 11.0 0.4 2.7 2 1 1 3 3 3 0 Methyltransferase domain PilI PF10623.4 ETO27518.1 - 0.014 15.3 0.0 0.041 13.8 0.0 1.8 1 0 0 1 1 1 0 Plasmid conjugative transfer protein PilI Ras PF00071.17 ETO27520.1 - 1.7e-11 43.8 0.0 4.2e-06 26.2 0.0 3.4 3 1 0 3 3 3 3 Ras family Miro PF08477.8 ETO27520.1 - 3.3e-05 24.3 0.4 0.22 12.0 0.0 2.4 1 1 1 2 2 2 2 Miro-like protein Arf PF00025.16 ETO27520.1 - 0.022 13.9 0.0 0.058 12.6 0.0 1.6 2 0 0 2 2 2 0 ADP-ribosylation factor family RabGAP-TBC PF00566.13 ETO27521.1 - 1.3e-31 109.8 2.5 1.3e-31 109.8 1.7 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Gti1_Pac2 PF09729.4 ETO27521.1 - 0.16 11.8 6.5 0.23 11.2 4.5 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family RP-C_C PF11800.3 ETO27521.1 - 1.2 8.8 9.2 1.7 8.3 6.3 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Band_3_cyto PF07565.8 ETO27521.1 - 1.2 8.5 7.8 1.7 8.0 5.4 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Serinc PF03348.10 ETO27521.1 - 1.4 7.5 5.9 2 7.0 4.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Hid1 PF12722.2 ETO27521.1 - 1.4 6.4 13.8 1.8 6.1 9.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.17 ETO27521.1 - 3.4 6.6 4.7 4.3 6.2 3.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter MFMR PF07777.6 ETO27521.1 - 5.9 6.7 7.8 8.5 6.2 5.4 1.2 1 0 0 1 1 1 0 G-box binding protein MFMR Cellulose_synt PF03552.9 ETO27521.1 - 6.2 4.9 6.4 8.3 4.5 4.4 1.1 1 0 0 1 1 1 0 Cellulose synthase WD40 PF00400.27 ETO27522.1 - 1.6e-29 100.6 11.5 2.4e-09 36.7 0.0 6.3 5 1 1 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 ETO27522.1 - 8.2e-08 32.1 1.3 1.5e-06 28.0 0.0 2.4 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Serinc PF03348.10 ETO27522.1 - 0.21 10.2 10.4 0.34 9.5 7.2 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Suf PF05843.9 ETO27522.1 - 0.6 9.7 20.9 1.1 8.9 14.5 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4407 PF14362.1 ETO27522.1 - 0.68 8.8 20.3 0.96 8.3 14.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIA PF03153.8 ETO27522.1 - 2.1 8.1 35.5 3.4 7.4 24.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FLO_LFY PF01698.11 ETO27522.1 - 3.9 6.2 16.2 6.1 5.5 11.2 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein RR_TM4-6 PF06459.7 ETO27522.1 - 4.2 7.1 18.9 6.8 6.4 13.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Med15 PF09606.5 ETO27522.1 - 7.7 4.5 52.4 10 4.1 36.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SprA-related PF12118.3 ETO27522.1 - 9.8 5.4 39.7 15 4.8 27.5 1.2 1 0 0 1 1 1 0 SprA-related family Peptidase_A21 PF03566.8 ETO27523.1 - 8.6 4.3 10.2 61 1.5 7.1 1.9 1 1 0 1 1 1 0 Peptidase family A21 DUF2258 PF10015.4 ETO27525.1 - 0.1 12.4 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2258) Vma12 PF11712.3 ETO27526.1 - 0.0015 18.2 0.4 0.0022 17.7 0.3 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Flu_NS2 PF00601.14 ETO27528.1 - 0.035 14.3 0.2 0.18 12.0 0.1 2.1 2 0 0 2 2 2 0 Influenza non-structural protein (NS2) WD40 PF00400.27 ETO27529.1 - 5.6e-21 73.5 3.0 2.5e-12 46.1 0.4 3.4 3 1 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO27529.1 - 0.0058 14.8 0.8 0.2 9.7 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Med19 PF10278.4 ETO27530.1 - 1 9.0 8.4 2.3 7.8 5.9 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Pkinase PF00069.20 ETO27531.1 - 4.8e-61 206.1 0.0 1.5e-60 204.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO27531.1 - 8.9e-30 103.6 0.0 1.8e-29 102.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 ETO27531.1 - 1.4e-19 67.8 23.5 3.4e-05 22.8 0.1 5.8 6 0 0 6 6 4 4 EF hand EF-hand_7 PF13499.1 ETO27531.1 - 8.3e-18 64.2 11.9 7.1e-09 35.6 1.8 3.7 2 1 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 ETO27531.1 - 1.7e-17 62.7 9.4 1.9e-05 24.1 0.5 5.1 3 1 2 5 5 5 4 EF-hand domain pair EF-hand_6 PF13405.1 ETO27531.1 - 5.5e-17 60.0 12.2 3.6e-05 23.2 0.1 5.5 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 ETO27531.1 - 3.7e-14 51.3 9.0 0.00011 21.4 0.0 5.0 4 0 0 4 4 4 4 EF hand EF-hand_4 PF12763.2 ETO27531.1 - 0.00024 20.7 0.2 0.21 11.3 0.2 3.0 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand APH PF01636.18 ETO27531.1 - 0.0008 19.2 0.0 0.078 12.6 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family EFhand_Ca_insen PF08726.5 ETO27531.1 - 0.0015 18.4 0.1 0.13 12.2 0.2 2.8 2 0 0 2 2 2 1 Ca2+ insensitive EF hand Kdo PF06293.9 ETO27531.1 - 0.016 14.2 0.0 0.037 13.0 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family U79_P34 PF03064.11 ETO27531.1 - 0.098 12.1 18.1 0.21 11.1 12.5 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Glycos_trans_3N PF02885.12 ETO27531.1 - 0.11 12.0 0.4 0.44 10.1 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain Mem_trans PF03547.13 ETO27531.1 - 0.22 9.7 0.1 0.25 9.5 0.1 1.2 1 0 0 1 1 1 0 Membrane transport protein RGS PF00615.14 ETO27532.1 - 3.7e-08 33.4 2.0 6.9e-08 32.6 1.4 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain MFS_1 PF07690.11 ETO27532.1 - 0.00048 18.9 3.1 0.00069 18.4 2.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TMEM154 PF15102.1 ETO27533.1 - 0.0031 17.2 3.7 0.0033 17.1 0.7 2.2 2 0 0 2 2 2 1 TMEM154 protein family Adeno_E3_CR2 PF02439.10 ETO27533.1 - 0.0092 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Dicty_REP PF05086.7 ETO27533.1 - 0.013 13.2 2.4 0.017 12.9 1.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein gpUL132 PF11359.3 ETO27533.1 - 0.015 14.6 3.4 0.027 13.8 2.3 1.5 1 0 0 1 1 1 0 Glycoprotein UL132 Syndecan PF01034.15 ETO27533.1 - 0.065 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain SAM_2 PF07647.12 ETO27533.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) JAB PF01398.16 ETO27534.1 - 0.0044 16.7 1.1 0.013 15.2 0.0 2.3 3 0 0 3 3 3 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease TetR_C_5 PF08360.6 ETO27534.1 - 0.057 13.3 0.2 0.12 12.3 0.2 1.5 1 0 0 1 1 1 0 QacR-like protein, C-terminal region Sulfotransfer_2 PF03567.9 ETO27535.1 - 1.9e-08 34.3 15.1 5.1e-05 23.0 5.7 2.4 1 1 1 2 2 2 2 Sulfotransferase family DUF1510 PF07423.6 ETO27536.1 - 0.0011 18.4 0.1 0.0014 18.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Zip PF02535.17 ETO27536.1 - 0.051 12.5 0.2 0.063 12.2 0.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Rhabdo_ncap PF00945.13 ETO27536.1 - 0.24 9.9 2.9 0.28 9.7 2.0 1.0 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein TFIIA PF03153.8 ETO27536.1 - 0.53 10.1 7.3 0.66 9.8 5.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2796 PF10986.3 ETO27536.1 - 2.5 8.0 11.0 3.3 7.6 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) CDC45 PF02724.9 ETO27536.1 - 4.1 5.3 11.6 4.8 5.1 8.0 1.0 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.11 ETO27536.1 - 4.2 6.2 6.8 5.3 5.9 4.7 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit BTV_NS2 PF04514.7 ETO27536.1 - 5.8 5.7 7.4 7.1 5.4 5.1 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF2457 PF10446.4 ETO27536.1 - 7.7 5.1 17.8 8.7 4.9 12.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) HMA PF00403.21 ETO27537.1 - 1e-07 32.0 7.7 0.00014 21.8 0.3 3.3 3 0 0 3 3 3 3 Heavy-metal-associated domain P4Ha_N PF08336.6 ETO27538.1 - 0.0079 16.0 1.8 0.031 14.0 0.3 2.4 2 0 0 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF1192 PF06698.6 ETO27538.1 - 0.19 11.5 4.0 5.7 6.8 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) IncA PF04156.9 ETO27538.1 - 0.25 10.9 2.0 0.55 9.7 1.4 1.6 1 0 0 1 1 1 0 IncA protein Fzo_mitofusin PF04799.8 ETO27538.1 - 0.7 9.2 5.9 2.7 7.3 1.8 2.4 1 1 1 2 2 2 0 fzo-like conserved region Inhibitor_I36 PF03995.8 ETO27538.1 - 0.84 10.0 4.3 8.9 6.7 0.2 2.6 2 0 0 2 2 2 0 Peptidase inhibitor family I36 DALR_1 PF05746.10 ETO27538.1 - 1.8 8.5 5.1 81 3.2 3.6 2.8 1 1 0 1 1 1 0 DALR anticodon binding domain Sigma70_ner PF04546.8 ETO27538.1 - 5.5 6.5 19.8 1.3 8.5 3.2 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region SYCE1 PF15233.1 ETO27539.1 - 0.0024 17.8 1.1 0.0046 16.8 0.8 1.5 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 WD40 PF00400.27 ETO27540.1 - 5.2e-76 248.0 8.9 1.8e-12 46.6 0.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO27540.1 - 2.9e-09 35.6 3.6 0.029 12.5 0.4 5.1 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO27540.1 - 9.9e-05 20.7 0.2 0.089 11.0 0.0 2.8 1 1 2 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO27540.1 - 0.00011 21.1 5.4 0.22 10.2 0.3 3.6 1 1 2 3 3 3 2 Nup133 N terminal like PD40 PF07676.7 ETO27540.1 - 0.00017 21.2 5.9 1 9.0 0.1 5.7 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 ETO27540.1 - 0.00024 20.3 2.5 4.7 6.2 0.0 4.5 1 1 4 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Resistin PF06954.6 ETO27540.1 - 0.00079 19.6 2.9 27 5.1 0.3 5.1 2 2 3 5 5 5 0 Resistin PQQ_2 PF13360.1 ETO27540.1 - 0.0013 18.2 0.2 0.15 11.4 0.0 2.6 1 1 1 2 2 2 1 PQQ-like domain DUF727 PF05303.7 ETO27540.1 - 0.0097 15.6 0.5 1.5 8.6 0.0 3.7 4 0 0 4 4 4 1 Protein of unknown function (DUF727) Proteasome_A_N PF10584.4 ETO27540.1 - 0.02 14.2 4.8 32 3.9 0.0 5.0 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature HARP PF07443.8 ETO27540.1 - 0.049 13.0 0.0 3.5 7.0 0.0 2.9 2 0 0 2 2 2 0 HepA-related protein (HARP) Ferritin PF00210.19 ETO27541.1 - 0.0052 16.5 0.2 0.015 15.0 0.2 1.8 1 0 0 1 1 1 1 Ferritin-like domain She9_MDM33 PF05546.6 ETO27541.1 - 0.5 9.8 8.0 0.37 10.3 0.2 2.8 3 0 0 3 3 3 0 She9 / Mdm33 family Spore_permease PF03845.8 ETO27542.1 - 0.001 17.8 1.0 0.001 17.8 0.7 1.7 2 0 0 2 2 2 1 Spore germination protein DUF4137 PF13593.1 ETO27542.1 - 0.0017 17.5 0.9 0.0017 17.5 0.6 1.7 2 0 0 2 2 2 1 SBF-like CPA transporter family (DUF4137) CK_II_beta PF01214.13 ETO27543.1 - 2e-11 43.7 0.5 5.5e-11 42.3 0.2 1.7 2 0 0 2 2 2 1 Casein kinase II regulatory subunit BLOC1_2 PF10046.4 ETO27544.1 - 0.027 14.6 1.1 0.027 14.6 0.8 5.2 1 1 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.6 ETO27544.1 - 0.095 12.5 0.2 0.095 12.5 0.1 4.5 2 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) GAS PF13851.1 ETO27544.1 - 0.1 11.7 55.0 1.1 8.4 12.2 3.3 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.3 ETO27544.1 - 1.4 6.1 38.7 3 5.0 26.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DASH_Dad1 PF08649.5 ETO27544.1 - 2.9 7.6 14.8 0.79 9.4 0.3 3.9 4 0 0 4 4 4 0 DASH complex subunit Dad1 dsrm PF00035.20 ETO27545.1 - 2e-07 31.4 0.1 2.9e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ufd2P_core PF10408.4 ETO27546.1 - 2.2e-64 217.8 7.9 2.8e-64 217.5 5.5 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core Ufd2P_core PF10408.4 ETO27547.1 - 1.7e-18 66.2 0.4 4e-18 65.0 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin elongating factor core CPSF100_C PF13299.1 ETO27549.1 - 2.5 8.2 8.0 3.7 7.7 5.5 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.12 ETO27549.1 - 2.6 6.7 6.3 3.3 6.4 4.4 1.1 1 0 0 1 1 1 0 Presenilin S1 PF00575.18 ETO27550.1 - 4.9e-11 42.5 0.2 0.00021 21.3 0.0 4.1 4 0 0 4 4 4 3 S1 RNA binding domain Pox_Ag35 PF03286.9 ETO27550.1 - 0.083 12.4 26.2 0.051 13.1 7.5 2.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DDHD PF02862.12 ETO27550.1 - 1.6 8.4 11.0 15 5.2 2.8 3.1 3 0 0 3 3 3 0 DDHD domain Daxx PF03344.10 ETO27550.1 - 4.7 5.5 30.7 0.023 13.2 6.3 2.1 2 0 0 2 2 2 0 Daxx Family CDC45 PF02724.9 ETO27550.1 - 5.4 4.9 26.4 3.1 5.7 4.7 2.1 2 0 0 2 2 2 0 CDC45-like protein S1 PF00575.18 ETO27551.1 - 0.00035 20.6 0.9 0.0018 18.3 0.6 2.3 1 1 0 1 1 1 1 S1 RNA binding domain TPR_19 PF14559.1 ETO27551.1 - 0.0035 17.6 0.0 0.15 12.4 0.0 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat Daxx PF03344.10 ETO27551.1 - 0.12 10.7 19.9 0.18 10.2 13.8 1.3 1 0 0 1 1 1 0 Daxx Family Suf PF05843.9 ETO27552.1 - 0.0012 18.6 0.7 0.082 12.6 0.2 2.1 1 1 1 2 2 2 2 Suppressor of forked protein (Suf) NRDE-2 PF08424.5 ETO27552.1 - 0.033 13.0 1.7 0.034 13.0 1.2 1.2 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Glyco_hydro_18 PF00704.23 ETO27553.1 - 1.5e-08 34.5 1.7 1.9e-08 34.1 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 TPR_11 PF13414.1 ETO27554.1 - 5.6e-32 109.2 14.3 1.1e-21 76.2 0.3 5.3 5 0 0 5 5 5 3 TPR repeat TPR_1 PF00515.23 ETO27554.1 - 3.7e-25 86.4 13.1 7.2e-05 22.2 0.1 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO27554.1 - 8.7e-22 75.2 10.1 9.1e-06 25.2 0.1 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 ETO27554.1 - 1.2e-14 54.0 0.9 0.00015 21.6 0.0 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO27554.1 - 1.3e-12 46.5 10.8 3e-05 23.4 0.4 5.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO27554.1 - 1.7e-08 33.9 4.9 0.054 13.7 0.1 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO27554.1 - 6.5e-08 33.0 1.5 0.00013 22.5 0.0 4.5 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO27554.1 - 1.7e-07 30.5 3.4 0.11 12.3 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO27554.1 - 2.2e-06 27.7 6.0 0.02 15.4 0.0 5.3 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETO27554.1 - 0.00023 20.9 0.0 0.0064 16.3 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO27554.1 - 0.00026 21.2 5.4 0.13 12.7 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO27554.1 - 0.0025 17.6 0.7 0.52 10.2 0.0 3.4 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.1 ETO27554.1 - 0.0081 16.4 1.3 0.23 11.8 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat Ycf1 PF05758.7 ETO27554.1 - 8.8 3.8 26.8 2.1 5.9 12.2 2.1 2 0 0 2 2 2 0 Ycf1 Thioredoxin_6 PF13848.1 ETO27555.1 - 3.3e-11 43.3 10.4 2.8e-06 27.2 0.2 4.5 3 2 1 4 4 4 3 Thioredoxin-like domain CHAT PF12770.2 ETO27557.1 - 3.1e-09 36.3 0.0 6.4e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 CHAT domain RskA PF10099.4 ETO27557.1 - 0.013 15.2 0.1 0.023 14.4 0.1 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Kelch_6 PF13964.1 ETO27558.1 - 4e-08 33.0 13.6 1.9e-05 24.6 0.3 5.2 5 1 1 6 6 6 2 Kelch motif Kelch_4 PF13418.1 ETO27558.1 - 2.3e-07 30.4 5.0 7.7e-05 22.3 0.0 4.1 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO27558.1 - 9.1e-06 25.1 23.7 0.0024 17.3 0.9 5.4 6 1 0 6 6 6 3 Kelch motif Kelch_3 PF13415.1 ETO27558.1 - 2.7e-05 24.2 0.0 0.092 12.9 0.0 3.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO27558.1 - 0.041 13.6 8.4 1.5 8.7 0.2 4.3 5 0 0 5 5 5 0 Kelch motif Kelch_5 PF13854.1 ETO27558.1 - 0.11 12.4 4.0 0.25 11.3 0.6 3.1 3 0 0 3 3 3 0 Kelch motif GF_recep_IV PF14843.1 ETO27558.1 - 0.99 9.0 8.8 0.03 13.9 1.7 1.6 2 0 0 2 2 2 0 Growth factor receptor domain IV MAPEG PF01124.13 ETO27559.1 - 1e-15 57.5 0.0 1.8e-15 56.7 0.0 1.4 1 1 0 1 1 1 1 MAPEG family Glyco_trans_2_3 PF13632.1 ETO27559.1 - 0.095 12.3 1.9 0.11 12.1 1.3 1.2 1 0 0 1 1 1 0 Glycosyl transferase family group 2 WD40 PF00400.27 ETO27560.1 - 5.4e-78 254.3 18.8 2.4e-13 49.3 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO27560.1 - 1e-08 33.7 0.3 0.11 10.6 0.0 4.4 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO27560.1 - 9.3e-07 27.4 0.4 0.0079 14.5 0.0 3.1 2 1 1 3 3 3 2 Cytochrome D1 heme domain PD40 PF07676.7 ETO27560.1 - 3.9e-05 23.1 5.9 2 8.1 0.0 6.5 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO27560.1 - 0.00049 19.6 0.4 0.36 10.2 0.1 3.8 1 1 1 2 2 2 2 PQQ-like domain SGL PF08450.7 ETO27560.1 - 0.0024 17.3 1.0 2.5 7.4 0.1 3.5 1 1 2 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region Proteasome_A_N PF10584.4 ETO27560.1 - 0.0028 16.9 2.7 3 7.2 0.0 5.4 6 0 0 6 6 6 1 Proteasome subunit A N-terminal signature DUF4488 PF14869.1 ETO27562.1 - 0.014 14.9 0.1 0.02 14.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4488) DUF3439 PF11921.3 ETO27562.1 - 0.07 12.8 5.4 0.1 12.3 3.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF936 PF06075.7 ETO27562.1 - 0.21 10.4 4.0 0.24 10.2 2.8 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) SSP160 PF06933.6 ETO27562.1 - 0.22 9.4 11.0 0.27 9.1 7.6 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.12 ETO27562.1 - 1.4 8.6 21.1 2.1 8.1 14.6 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF4512 PF14975.1 ETO27563.1 - 0.051 14.4 0.3 0.13 13.0 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4512) Mrr_N PF14338.1 ETO27567.1 - 0.0041 17.1 1.2 0.27 11.3 0.0 2.9 2 1 1 3 3 3 1 Mrr N-terminal domain DUF2207 PF09972.4 ETO27567.1 - 0.095 11.2 0.1 0.12 10.8 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Pex24p PF06398.6 ETO27567.1 - 0.24 10.1 2.3 0.32 9.7 1.6 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin TACC PF05010.9 ETO27568.1 - 0.025 14.3 0.3 0.027 14.2 0.2 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) Rxt3 PF08642.5 ETO27569.1 - 0.065 13.4 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 PTH2 PF01981.11 ETO27570.1 - 5.8e-32 109.7 1.4 4.4e-30 103.7 1.0 2.8 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 NdhL PF10716.4 ETO27571.1 - 2.1 8.1 6.5 3.7 7.3 4.5 1.4 1 0 0 1 1 1 0 NADH dehydrogenase transmembrane subunit DUF4125 PF13526.1 ETO27572.1 - 0.024 14.1 0.1 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4125) Ank_2 PF12796.2 ETO27573.1 - 3.4e-33 113.8 11.7 5.5e-16 58.6 0.8 3.9 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 ETO27573.1 - 1.5e-26 90.8 3.2 1.6e-11 43.3 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 ETO27573.1 - 2.9e-22 76.5 3.8 1.5e-08 34.0 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 ETO27573.1 - 2.3e-19 69.3 2.9 8.2e-12 45.3 0.2 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO27573.1 - 1.9e-16 59.7 23.0 3.5e-07 30.2 0.0 5.6 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Nop53 PF07767.6 ETO27575.1 - 0.0067 15.4 24.6 0.0067 15.4 17.1 3.4 3 0 0 3 3 3 2 Nop53 (60S ribosomal biogenesis) SR-25 PF10500.4 ETO27575.1 - 0.081 12.3 44.1 0.036 13.5 15.3 3.2 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF2663 PF10864.3 ETO27579.1 - 0.0037 17.4 4.9 0.059 13.5 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2663) Peptidase_U4 PF03419.8 ETO27579.1 - 1.5 7.7 12.0 0.56 9.2 4.1 2.0 1 1 1 2 2 2 0 Sporulation factor SpoIIGA DUF3816 PF12822.2 ETO27579.1 - 3.1 7.6 12.1 16 5.3 8.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) Pkinase PF00069.20 ETO27580.1 - 9e-31 106.9 0.6 9.2e-19 67.5 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO27580.1 - 7.2e-14 51.4 0.0 2.2e-06 26.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 ETO27580.1 - 0.0023 18.4 0.3 0.0043 17.5 0.2 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain IFT57 PF10498.4 ETO27581.1 - 5.3e-39 133.9 14.2 8.9e-39 133.2 9.9 1.3 1 1 0 1 1 1 1 Intra-flagellar transport protein 57 FANCI_S4 PF14678.1 ETO27581.1 - 0.042 12.9 0.3 0.12 11.4 0.0 1.8 2 0 0 2 2 2 0 FANCI solenoid 4 DUF4628 PF15429.1 ETO27582.1 - 0.021 14.2 0.2 0.15 11.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4628) RGS PF00615.14 ETO27583.1 - 0.013 15.6 0.2 0.69 10.0 0.0 2.2 2 0 0 2 2 2 0 Regulator of G protein signaling domain ECH PF00378.15 ETO27584.1 - 3.7e-13 49.1 0.0 6.1e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_M41 PF01434.13 ETO27585.1 - 2.6e-57 193.7 0.2 1.7e-52 178.0 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M41 Meth_synt_1 PF08267.7 ETO27588.1 - 0.062 12.5 0.3 0.077 12.2 0.2 1.1 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain TEX19 PF15553.1 ETO27588.1 - 2.3 8.0 7.1 1.5 8.6 2.1 2.0 2 0 0 2 2 2 0 Testis-expressed protein 19 Peptidase_C93 PF06035.6 ETO27592.1 - 0.15 11.4 2.1 4.6 6.6 0.1 2.2 2 0 0 2 2 2 0 Bacterial transglutaminase-like cysteine proteinase BTLCP Menin PF05053.8 ETO27594.1 - 0.049 11.8 9.9 0.077 11.1 6.8 1.2 1 0 0 1 1 1 0 Menin ABC2_membrane_3 PF12698.2 ETO27594.1 - 0.96 8.4 5.0 1 8.3 3.5 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Mucin PF01456.12 ETO27594.1 - 1.8 8.3 10.9 2.9 7.6 7.6 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Paramyxo_ncap PF00973.14 ETO27594.1 - 8.7 4.9 8.7 15 4.1 6.1 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein TB2_DP1_HVA22 PF03134.14 ETO27595.1 - 8.5e-10 38.2 0.4 1.9e-09 37.1 0.1 1.7 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Glycos_transf_1 PF00534.15 ETO27596.1 - 3.7e-35 120.8 0.0 2.5e-17 62.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 ETO27596.1 - 1.1e-21 77.3 0.0 5.9e-10 39.4 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 ETO27596.1 - 7.5e-08 32.5 0.0 0.00019 21.6 0.0 2.9 2 1 0 2 2 2 2 Glycosyl transferases group 1 Gaa1 PF04114.9 ETO27596.1 - 0.0004 19.2 0.1 0.00087 18.1 0.1 1.4 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Glyco_transf_4 PF13439.1 ETO27596.1 - 0.0031 17.2 0.2 1.6 8.4 0.1 2.9 2 0 0 2 2 2 2 Glycosyltransferase Family 4 SMC_hinge PF06470.8 ETO27597.1 - 3.5e-25 88.3 0.4 2.8e-24 85.3 0.0 2.9 4 0 0 4 4 4 1 SMC proteins Flexible Hinge Domain SMC_N PF02463.14 ETO27597.1 - 1.9e-21 76.3 27.5 2.9e-21 75.7 19.1 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETO27597.1 - 3.1e-07 30.6 1.2 4.1e-06 26.9 0.8 2.6 1 1 0 1 1 1 1 AAA domain Reo_sigmaC PF04582.7 ETO27597.1 - 0.0041 16.3 19.0 0.032 13.4 1.1 3.3 3 0 0 3 3 3 2 Reovirus sigma C capsid protein Laminin_II PF06009.7 ETO27597.1 - 0.012 15.3 6.9 0.012 15.3 4.8 5.3 2 1 2 5 5 5 0 Laminin Domain II IncA PF04156.9 ETO27597.1 - 0.038 13.5 79.2 0.14 11.7 12.7 4.6 2 1 2 4 4 4 0 IncA protein DEAD PF00270.24 ETO27597.1 - 0.079 12.4 3.0 0.95 8.9 0.0 2.8 2 0 0 2 2 2 0 DEAD/DEAH box helicase Peptidase_C14 PF00656.17 ETO27598.1 - 2.4e-13 50.3 0.5 2.4e-13 50.3 0.4 2.0 2 0 0 2 2 2 1 Caspase domain Caleosin PF05042.8 ETO27598.1 - 0.31 10.5 0.0 0.31 10.5 0.0 2.5 3 0 0 3 3 3 0 Caleosin related protein Daxx PF03344.10 ETO27598.1 - 0.63 8.4 13.8 0.81 8.0 9.6 1.1 1 0 0 1 1 1 0 Daxx Family PaREP1 PF05942.6 ETO27600.1 - 0.022 14.6 2.6 0.23 11.3 0.3 2.6 2 0 0 2 2 2 0 Archaeal PaREP1/PaREP8 family Hist_deacetyl PF00850.14 ETO27601.1 - 1.4e-30 106.6 0.2 1.9e-30 106.2 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Draxin PF15550.1 ETO27602.1 - 0.02 14.6 0.5 0.022 14.4 0.4 1.1 1 0 0 1 1 1 0 Draxin DUF1019 PF06254.6 ETO27602.1 - 0.027 14.6 0.0 0.042 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1019) Metallophos PF00149.23 ETO27603.1 - 1.2e-05 24.8 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 ETO27603.1 - 0.0037 17.1 0.0 0.0039 17.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PHD PF00628.24 ETO27604.1 - 1.8e-07 30.7 11.8 3.2e-07 29.9 8.2 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 ETO27604.1 - 0.00025 20.2 2.7 0.00048 19.3 1.8 1.5 1 0 0 1 1 1 1 PHD-finger C1_3 PF07649.7 ETO27604.1 - 1.3 9.1 6.2 2.6 8.1 4.3 1.6 1 0 0 1 1 1 0 C1-like domain TPR_16 PF13432.1 ETO27605.1 - 0.096 13.3 0.2 0.096 13.3 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Vpu PF00558.14 ETO27605.1 - 1.7 8.2 7.5 0.08 12.5 0.6 2.2 2 0 0 2 2 2 0 Vpu protein Acyl-thio_N PF12590.3 ETO27605.1 - 7.4 7.0 17.7 0.11 12.9 1.4 3.0 3 1 0 3 3 3 0 Acyl-ATP thioesterase TPR_12 PF13424.1 ETO27606.1 - 2.9e-26 91.2 1.3 4.7e-12 45.6 0.1 2.4 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO27606.1 - 7.4e-20 70.3 17.8 7.9e-08 31.8 0.5 2.9 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETO27606.1 - 1.6e-18 65.4 14.1 1.8e-09 36.8 1.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO27606.1 - 3.7e-18 63.8 5.7 2e-08 33.4 0.3 4.7 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO27606.1 - 1.3e-15 56.7 0.9 4.5e-06 26.4 0.2 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO27606.1 - 3.7e-15 54.5 13.4 3.4e-07 29.6 0.8 4.5 3 1 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO27606.1 - 3.7e-12 45.0 11.2 9.8e-05 21.8 0.3 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO27606.1 - 1.1e-05 25.1 10.1 0.038 14.1 0.4 4.4 2 1 1 3 3 3 2 Tetratricopeptide repeat SNAP PF14938.1 ETO27606.1 - 2e-05 23.8 5.7 0.0019 17.3 0.4 1.9 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_16 PF13432.1 ETO27606.1 - 3.1e-05 24.5 0.0 0.00029 21.4 0.0 2.4 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO27606.1 - 4.9e-05 23.6 0.2 0.28 11.9 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO27606.1 - 0.0002 21.4 4.7 0.0018 18.3 2.2 2.8 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 ETO27606.1 - 0.00034 20.4 7.0 0.021 14.7 0.3 3.7 3 1 1 4 4 4 2 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 ETO27606.1 - 0.0013 19.0 5.2 1 9.9 0.1 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat DUF2225 PF09986.4 ETO27606.1 - 0.0063 15.9 2.8 0.83 9.0 0.1 2.3 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_3 PF07720.7 ETO27606.1 - 0.019 14.7 9.0 0.048 13.4 2.6 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF627 PF04781.7 ETO27606.1 - 0.032 13.8 0.6 2 8.0 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF627) UFD1 PF03152.9 ETO27608.1 - 1.8e-34 118.4 0.0 2.4e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 ETO27608.1 - 5.3e-05 22.7 0.1 0.00059 19.4 0.0 2.2 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 RTX_C PF08339.5 ETO27609.1 - 0.035 13.8 1.2 0.057 13.1 0.8 1.3 1 0 0 1 1 1 0 RTX C-terminal domain DUF1043 PF06295.7 ETO27609.1 - 0.089 12.4 1.7 0.11 12.0 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) CAP_N PF01213.14 ETO27610.1 - 1.1e-11 44.6 0.1 1.3e-11 44.3 0.0 1.0 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal Ribosomal_60s PF00428.14 ETO27610.1 - 0.00078 19.8 2.0 0.0011 19.3 1.4 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3231 PF11553.3 ETO27610.1 - 0.078 12.4 0.1 0.098 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3231) CAP_N PF01213.14 ETO27611.1 - 0.026 13.8 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PP2C PF00481.16 ETO27612.1 - 5.1e-24 85.0 0.0 3.3e-23 82.3 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C FlgN PF05130.7 ETO27613.1 - 0.8 9.9 15.2 0.15 12.3 6.6 2.3 2 0 0 2 2 2 0 FlgN protein CAP_GLY PF01302.20 ETO27614.1 - 4e-95 311.5 34.6 2.5e-20 71.9 0.4 7.2 7 0 0 7 7 7 7 CAP-Gly domain DUF3189 PF11385.3 ETO27614.1 - 0.0058 16.1 0.9 0.15 11.6 0.1 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3189) YajC PF02699.10 ETO27614.1 - 4.7 6.9 16.6 20 4.9 0.1 5.9 7 0 0 7 7 7 0 Preprotein translocase subunit EF-hand_6 PF13405.1 ETO27615.1 - 2.1e-08 33.3 3.7 0.25 11.3 0.0 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 ETO27615.1 - 2.8e-05 24.1 5.8 0.0076 16.3 1.5 3.8 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 ETO27615.1 - 0.0039 16.3 13.2 0.18 11.1 0.1 5.1 5 0 0 5 5 5 2 EF hand EF-hand_5 PF13202.1 ETO27615.1 - 0.33 10.3 8.2 2 7.8 0.3 3.7 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.1 ETO27615.1 - 0.53 9.9 9.2 0.79 9.3 0.3 3.5 3 0 0 3 3 3 0 EF-hand domain pair RPEL PF02755.10 ETO27616.1 - 2.2e-06 26.8 5.5 0.0006 19.0 0.2 4.4 4 0 0 4 4 4 1 RPEL repeat Phage_glycop_gL PF11108.3 ETO27616.1 - 2.8 7.9 8.3 2.4 8.1 0.1 3.2 1 1 0 2 2 2 0 Viral glycoprotein L DUF725 PF05267.7 ETO27616.1 - 8.1 6.3 16.6 3.2 7.6 6.5 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF725) DUF3357 PF11837.3 ETO27617.1 - 0.0037 17.0 1.9 0.12 12.2 0.2 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF3357) DUF1235 PF06822.7 ETO27617.1 - 0.019 13.9 0.3 0.024 13.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1235) GRP PF07172.6 ETO27617.1 - 0.59 10.6 2.0 0.74 10.3 0.1 1.9 2 0 0 2 2 2 0 Glycine rich protein family ATP-synt_8 PF00895.15 ETO27617.1 - 0.74 10.0 11.1 3.1 8.0 2.5 2.3 2 0 0 2 2 2 0 ATP synthase protein 8 ETRAMP PF09716.5 ETO27617.1 - 1.4 8.9 7.3 0.16 11.9 0.3 2.1 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) PH PF00169.24 ETO27618.1 - 0.00034 20.7 0.0 0.00076 19.6 0.0 1.7 1 0 0 1 1 1 1 PH domain CAAD PF14159.1 ETO27619.1 - 0.073 12.7 4.0 1.2 8.8 0.8 2.8 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase RGS PF00615.14 ETO27620.1 - 3.4e-06 27.1 0.3 0.0097 16.0 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain TFIIA PF03153.8 ETO27620.1 - 0.024 14.5 13.7 0.031 14.1 9.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PSCyt3 PF07627.6 ETO27620.1 - 0.092 12.6 3.1 0.32 10.8 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1588) Mito_fiss_reg PF05308.6 ETO27620.1 - 0.36 10.1 10.8 0.093 12.0 5.2 1.7 2 0 0 2 2 2 0 Mitochondrial fission regulator Zip PF02535.17 ETO27620.1 - 0.49 9.3 2.7 0.69 8.8 1.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Ribosomal_60s PF00428.14 ETO27621.1 - 1.6e-11 44.4 21.9 1e-10 41.8 15.2 1.9 1 1 0 1 1 1 1 60s Acidic ribosomal protein Jag_N PF14804.1 ETO27621.1 - 0.00023 21.1 0.1 0.00043 20.2 0.0 1.5 1 0 0 1 1 1 1 Jag N-terminus DUF1525 PF07511.6 ETO27621.1 - 0.058 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) DUF1168 PF06658.7 ETO27623.1 - 0.98 8.9 52.1 0.35 10.3 11.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) Utp14 PF04615.8 ETO27623.1 - 1.6 6.8 46.1 1.8 6.6 31.9 1.0 1 0 0 1 1 1 0 Utp14 protein Prog_receptor PF02161.10 ETO27623.1 - 2.8 6.6 8.9 3.6 6.3 6.2 1.3 1 0 0 1 1 1 0 Progesterone receptor 2OG-FeII_Oxy_2 PF13532.1 ETO27624.1 - 3.7e-15 56.2 0.0 1.1e-14 54.7 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_polyA_pol PF03296.8 ETO27625.1 - 0.29 10.6 0.1 0.29 10.6 0.1 1.6 2 0 0 2 2 2 0 Poxvirus poly(A) polymerase nucleotidyltransferase domain ABC_tran PF00005.22 ETO27626.1 - 1.9e-29 102.7 0.1 5.1e-29 101.3 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 ETO27626.1 - 2.9e-10 40.5 0.1 2.1e-07 31.2 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 ETO27626.1 - 0.0045 17.3 1.4 0.015 15.6 0.1 2.0 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 ETO27626.1 - 0.0061 15.8 0.0 1 8.5 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 ETO27626.1 - 0.0063 16.0 0.1 0.014 14.8 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 ETO27626.1 - 0.013 15.4 0.0 0.074 12.9 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit UPF0079 PF02367.12 ETO27626.1 - 0.057 13.0 0.2 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ABC2_membrane_3 PF12698.2 ETO27627.1 - 4.5e-28 98.2 15.2 6.5e-28 97.7 10.6 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein TMEM192 PF14802.1 ETO27627.1 - 0.3 9.9 8.0 0.17 10.6 2.6 2.0 2 0 0 2 2 2 0 TMEM192 family DUF3112 PF11309.3 ETO27627.1 - 2 8.2 9.4 0.69 9.6 4.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3112) Diphthamide_syn PF01866.12 ETO27629.1 - 8.3e-94 314.2 0.0 1.9e-93 313.0 0.0 1.6 1 1 0 1 1 1 1 Putative diphthamide synthesis protein Tom22 PF04281.8 ETO27630.1 - 0.0061 16.0 9.2 0.0061 16.0 6.4 2.5 2 0 0 2 2 2 1 Mitochondrial import receptor subunit Tom22 Ycf1 PF05758.7 ETO27630.1 - 0.06 11.0 10.0 0.078 10.6 7.0 1.3 1 0 0 1 1 1 0 Ycf1 Zip PF02535.17 ETO27630.1 - 1.1 8.1 4.3 2.2 7.2 3.0 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter SprA-related PF12118.3 ETO27630.1 - 1.1 8.4 24.3 1.8 7.7 16.9 1.3 1 0 0 1 1 1 0 SprA-related family Borrelia_P83 PF05262.6 ETO27630.1 - 2.2 6.4 19.4 3.8 5.6 13.5 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein CDC45 PF02724.9 ETO27630.1 - 2.7 5.9 13.8 5.6 4.8 9.6 1.4 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.11 ETO27630.1 - 4.7 6.1 10.8 9.9 5.0 7.5 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Lin-8 PF03353.10 ETO27631.1 - 0.087 12.0 1.4 0.11 11.7 1.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Pkinase PF00069.20 ETO27632.1 - 1.6e-29 102.8 1.3 2.7e-23 82.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO27632.1 - 3.3e-11 42.7 0.0 5.7e-11 41.9 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Mre11_DNA_bind PF04152.9 ETO27634.1 - 0.0015 18.3 2.3 2.6 7.8 0.0 2.5 2 0 0 2 2 2 2 Mre11 DNA-binding presumed domain Ribosomal_60s PF00428.14 ETO27634.1 - 0.01 16.2 3.6 0.017 15.4 2.5 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Spot_14 PF07084.7 ETO27634.1 - 0.013 15.3 1.2 0.028 14.2 0.8 1.5 1 0 0 1 1 1 0 Thyroid hormone-inducible hepatic protein Spot 14 GOLD_2 PF13897.1 ETO27634.1 - 0.045 13.9 0.7 0.085 13.0 0.5 1.4 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking FAM176 PF14851.1 ETO27634.1 - 0.076 12.6 3.1 1.1 8.9 1.5 2.5 2 0 0 2 2 2 0 FAM176 family Myc_N PF01056.13 ETO27634.1 - 0.11 11.5 3.4 0.19 10.8 2.3 1.3 1 0 0 1 1 1 0 Myc amino-terminal region BSP_II PF05432.6 ETO27634.1 - 2 7.6 7.8 3.4 6.8 5.4 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF3682 PF12446.3 ETO27634.1 - 2.6 8.3 7.1 5.5 7.2 5.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DUF2075 PF09848.4 ETO27635.1 - 0.048 12.6 0.1 0.055 12.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) tRNA_edit PF04073.10 ETO27635.1 - 0.14 11.9 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Aminoacyl-tRNA editing domain DUF869 PF05911.6 ETO27636.1 - 0.48 8.5 139.1 0.0079 14.4 8.2 6.1 5 1 1 6 6 6 0 Plant protein of unknown function (DUF869) Lge1 PF11488.3 ETO27636.1 - 2.4 8.4 0.0 2.4 8.4 0.0 10.2 6 3 3 9 9 9 0 Transcriptional regulatory protein LGE1 Filament PF00038.16 ETO27636.1 - 4.1 6.7 151.0 0.041 13.3 27.2 7.5 4 2 4 8 8 8 0 Intermediate filament protein Rsm1 PF08600.5 ETO27638.1 - 8.1 6.3 8.1 34 4.3 5.6 2.2 1 1 0 1 1 1 0 Rsm1-like WW PF00397.21 ETO27639.1 - 0.052 13.4 0.3 0.093 12.6 0.2 1.4 1 0 0 1 1 1 0 WW domain DUF3713 PF12506.3 ETO27639.1 - 0.1 12.6 0.2 0.1 12.6 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3713) Tropomyosin PF00261.15 ETO27639.1 - 0.11 11.5 18.8 1.3 8.0 9.4 2.3 2 0 0 2 2 2 0 Tropomyosin FAD-SLDH PF12318.3 ETO27639.1 - 0.15 11.7 2.3 0.3 10.7 1.6 1.5 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase Autophagy_N PF03986.8 ETO27639.1 - 0.16 11.7 4.3 0.28 10.9 3.0 1.3 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain Sipho_Gp157 PF05565.6 ETO27639.1 - 0.31 10.5 17.1 0.031 13.8 7.0 2.3 2 0 0 2 2 2 0 Siphovirus Gp157 Hormone_1 PF00103.15 ETO27639.1 - 0.42 9.9 11.0 0.81 8.9 7.5 1.5 1 1 0 1 1 1 0 Somatotropin hormone family DUF4140 PF13600.1 ETO27639.1 - 0.42 11.0 10.3 37 4.8 0.0 3.3 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) FlaC_arch PF05377.6 ETO27639.1 - 0.47 10.3 5.5 1.5 8.7 3.3 2.4 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF3450 PF11932.3 ETO27639.1 - 1 8.5 15.4 0.46 9.7 8.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF802 PF05650.6 ETO27639.1 - 1.1 9.4 4.6 41 4.3 0.3 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF802) ApoO PF09769.4 ETO27639.1 - 1.1 8.9 6.1 0.54 9.9 2.4 1.8 3 0 0 3 3 3 0 Apolipoprotein O Baculo_PEP_C PF04513.7 ETO27639.1 - 1.3 8.8 7.7 0.32 10.8 2.5 1.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2229 PF09989.4 ETO27639.1 - 1.9 7.9 8.9 1.4 8.3 4.9 1.4 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) AAA_23 PF13476.1 ETO27639.1 - 2.8 8.2 26.7 1.9 8.7 16.6 2.1 1 1 0 1 1 1 0 AAA domain CmcH_NodU PF02543.10 ETO27639.1 - 2.8 6.9 6.5 1.9 7.5 3.5 1.4 1 1 0 1 1 1 0 Carbamoyltransferase ADIP PF11559.3 ETO27639.1 - 2.9 7.7 25.4 1.6 8.5 12.3 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Tropomyosin_1 PF12718.2 ETO27639.1 - 8.3 6.2 28.3 0.52 10.1 13.5 2.2 2 0 0 2 2 2 0 Tropomyosin like TMF_DNA_bd PF12329.3 ETO27639.1 - 8.6 6.2 30.5 0.17 11.6 14.3 2.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding RGS PF00615.14 ETO27640.1 - 2.3e-08 34.1 1.5 5e-08 33.0 1.1 1.7 1 1 0 1 1 1 1 Regulator of G protein signaling domain Metallophos PF00149.23 ETO27641.1 - 0.00014 21.2 0.0 0.00022 20.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DASH_Spc34 PF08657.5 ETO27641.1 - 0.033 13.8 1.0 0.042 13.5 0.7 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 DUF4614 PF15391.1 ETO27641.1 - 2.6 7.7 6.4 3.8 7.2 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Apt1 PF10351.4 ETO27641.1 - 4.8 5.9 9.7 5.8 5.6 6.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Mucin PF01456.12 ETO27641.1 - 7.6 6.2 11.9 11 5.8 8.2 1.3 1 1 0 1 1 1 0 Mucin-like glycoprotein ZZ PF00569.12 ETO27642.1 - 0.025 14.1 0.7 0.058 12.9 0.5 1.6 1 0 0 1 1 1 0 Zinc finger, ZZ type WD40 PF00400.27 ETO27644.1 - 4.5e-07 29.5 0.3 0.015 15.1 0.2 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat PQQ_3 PF13570.1 ETO27644.1 - 0.046 14.0 0.0 12 6.3 0.0 3.1 3 0 0 3 3 3 0 PQQ-like domain HCV_NS5a PF01506.14 ETO27644.1 - 1.6 8.4 6.9 0.57 9.8 0.8 2.4 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a protein membrane anchor Kinesin PF00225.18 ETO27645.1 - 7.9e-21 74.1 0.2 7.9e-21 74.1 0.1 3.1 4 1 1 5 5 5 1 Kinesin motor domain DivIC PF04977.10 ETO27645.1 - 0.00033 20.0 1.0 0.00033 20.0 0.7 8.3 4 1 2 7 7 7 2 Septum formation initiator TMEM190 PF15431.1 ETO27647.1 - 0.032 14.1 0.6 0.1 12.5 0.2 1.9 2 0 0 2 2 2 0 Transmembrane protein 190 YtpI PF14007.1 ETO27647.1 - 0.36 10.7 7.8 0.044 13.6 1.5 2.2 2 0 0 2 2 2 0 YtpI-like protein DBB PF14545.1 ETO27649.1 - 0.014 14.8 0.2 0.021 14.3 0.1 1.4 1 0 0 1 1 1 0 Dof, BCAP, and BANK (DBB) motif, DUF2522 PF10747.4 ETO27649.1 - 2.1 8.3 8.3 2.5 8.1 3.6 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2522) PPR_3 PF13812.1 ETO27650.1 - 0.0013 18.8 0.1 0.11 12.8 0.0 3.2 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR PF01535.15 ETO27650.1 - 0.0035 17.1 0.5 5.3 7.2 0.0 3.3 3 0 0 3 3 3 2 PPR repeat PPR_2 PF13041.1 ETO27650.1 - 0.0036 17.2 0.4 4.2 7.4 0.0 3.9 2 1 1 3 3 3 1 PPR repeat family Peptidase_M13 PF01431.16 ETO27650.1 - 0.009 15.2 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 DUF1400 PF07176.6 ETO27650.1 - 0.03 14.2 0.1 0.18 11.7 0.0 2.1 2 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) DUF4004 PF13171.1 ETO27650.1 - 0.034 14.2 0.2 0.064 13.4 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4004) DUF724 PF05266.9 ETO27650.1 - 0.064 12.8 0.3 0.097 12.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF3043 PF11241.3 ETO27651.1 - 0.079 12.5 2.6 0.17 11.4 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DUF2981 PF11200.3 ETO27651.1 - 5.9 5.8 16.4 14 4.6 11.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Serinc PF03348.10 ETO27651.1 - 6 5.4 7.9 11 4.5 5.5 1.5 1 0 0 1 1 1 0 Serine incorporator (Serinc) Atrophin-1 PF03154.10 ETO27651.1 - 8.4 4.3 9.7 14 3.6 6.7 1.2 1 0 0 1 1 1 0 Atrophin-1 family UPF0061 PF02696.9 ETO27652.1 - 1.5e-35 122.5 10.1 1.3e-22 79.7 0.1 3.0 2 1 0 3 3 3 3 Uncharacterized ACR, YdiU/UPF0061 family DUF2729 PF10870.3 ETO27652.1 - 0.01 15.5 1.4 0.041 13.6 1.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2729) DUF3585 PF12130.3 ETO27652.1 - 0.42 10.4 3.8 7.8 6.3 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3585) IncA PF04156.9 ETO27653.1 - 0.003 17.1 6.2 0.003 17.1 4.3 3.5 2 1 0 3 3 3 1 IncA protein DUF3533 PF12051.3 ETO27653.1 - 0.0038 16.0 2.8 0.014 14.1 1.9 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) CDC27 PF09507.5 ETO27654.1 - 6.3 5.9 32.8 0.54 9.4 18.6 1.8 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 ADH_zinc_N PF00107.21 ETO27655.1 - 6.9e-22 77.3 0.2 5.3e-21 74.5 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETO27655.1 - 0.017 14.9 1.9 0.035 13.8 1.3 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.14 ETO27655.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPR_11 PF13414.1 ETO27656.1 - 2.5e-09 36.6 0.1 0.009 15.6 0.0 3.5 3 0 0 3 3 3 3 TPR repeat TPR_12 PF13424.1 ETO27656.1 - 6.6e-05 22.7 0.3 0.031 14.1 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO27656.1 - 0.0028 18.1 0.0 81 4.2 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETO27656.1 - 0.0069 16.2 0.1 0.96 9.5 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETO27656.1 - 0.06 13.1 0.0 6 6.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat MerR_1 PF13411.1 ETO27657.1 - 0.02 14.6 0.0 0.044 13.5 0.0 1.6 1 0 0 1 1 1 0 MerR HTH family regulatory protein TRP PF06011.7 ETO27657.1 - 0.048 12.2 1.2 0.07 11.6 0.8 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel HTH_Tnp_1 PF01527.15 ETO27657.1 - 0.1 12.5 5.3 0.15 11.9 0.0 3.1 3 0 0 3 3 3 0 Transposase HTH_23 PF13384.1 ETO27657.1 - 0.12 12.0 1.0 0.35 10.6 0.1 2.3 2 0 0 2 2 2 0 Homeodomain-like domain FLYWCH PF04500.11 ETO27658.1 - 3.2 7.6 6.1 0.35 10.8 0.9 2.0 2 0 0 2 2 2 0 FLYWCH zinc finger domain Calci_bind_CcbP PF11535.3 ETO27660.1 - 0.031 14.5 0.0 0.031 14.5 0.0 2.2 3 0 0 3 3 3 0 Calcium binding zf-C2H2 PF00096.21 ETO27662.1 - 4.2e-09 36.2 24.3 4.1e-05 23.6 0.8 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETO27662.1 - 1.1e-06 28.6 17.0 1.2e-05 25.3 2.3 4.3 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 ETO27662.1 - 5.6e-06 26.3 21.0 0.0057 16.9 0.8 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 ETO27662.1 - 0.016 15.3 20.3 0.91 9.7 0.9 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding PhnJ PF06007.6 ETO27662.1 - 0.025 13.3 1.3 0.15 10.7 0.3 2.0 1 1 1 2 2 2 0 Phosphonate metabolism protein PhnJ Apc13p PF05839.6 ETO27662.1 - 0.072 13.0 0.6 0.17 11.8 0.4 1.6 1 0 0 1 1 1 0 Apc13p protein zf-Di19 PF05605.7 ETO27662.1 - 0.23 11.6 10.6 1.2 9.2 1.8 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 ETO27662.1 - 0.25 11.6 15.9 0.5 10.6 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type XPA_N PF01286.13 ETO27662.1 - 2.3 7.9 6.3 1.6 8.4 0.1 2.9 3 0 0 3 3 3 0 XPA protein N-terminal zf-C2H2_2 PF12756.2 ETO27662.1 - 2.4 8.3 12.3 2 8.5 0.7 3.4 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 ETO27662.1 - 3.2 7.5 18.4 2.8 7.7 0.5 3.4 2 1 1 3 3 3 0 BED zinc finger FYVE PF01363.16 ETO27662.1 - 3.6 7.5 9.8 0.54 10.1 2.3 2.5 1 1 1 2 2 2 0 FYVE zinc finger Zn_ribbon_recom PF13408.1 ETO27662.1 - 7.4 6.9 10.2 1.9 8.8 2.0 2.5 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Cript PF10235.4 ETO27662.1 - 8.1 6.8 11.3 2.4 8.5 2.0 2.9 3 1 0 3 3 3 0 Microtubule-associated protein CRIPT CENP-B_dimeris PF09026.5 ETO27663.1 - 5.7 7.2 14.3 0.29 11.3 1.0 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain LRR_6 PF13516.1 ETO27665.1 - 0.0078 16.1 0.4 18 5.8 0.0 3.6 4 0 0 4 4 4 2 Leucine Rich repeat Pox_Ag35 PF03286.9 ETO27665.1 - 0.032 13.7 3.7 0.057 12.9 2.6 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CAP-ZIP_m PF15255.1 ETO27665.1 - 0.079 12.8 1.5 0.13 12.1 1.0 1.3 1 0 0 1 1 1 0 WASH complex subunit CAP-Z interacting, central region DUF3388 PF11868.3 ETO27666.1 - 0.007 15.5 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3388) Eapp_C PF10238.4 ETO27668.1 - 4.5e-08 33.0 15.1 4.5e-08 33.0 10.5 2.9 3 1 0 3 3 3 1 E2F-associated phosphoprotein Yippee-Mis18 PF03226.9 ETO27668.1 - 3.1e-05 23.9 4.0 0.00034 20.6 2.8 2.2 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DGF-1_C PF11040.3 ETO27668.1 - 0.016 15.0 1.8 0.077 12.8 1.3 2.2 1 1 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus COX16 PF14138.1 ETO27668.1 - 0.089 12.9 1.1 0.65 10.2 0.0 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 DUF1980 PF09323.5 ETO27669.1 - 0.077 12.7 0.4 0.13 11.9 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) PaREP1 PF05942.6 ETO27669.1 - 0.099 12.5 0.1 0.5 10.2 0.1 2.0 2 0 0 2 2 2 0 Archaeal PaREP1/PaREP8 family Helicase_RecD PF05127.9 ETO27670.1 - 2.3e-56 190.2 0.0 5e-55 185.8 0.0 2.8 2 1 0 2 2 2 1 Helicase GNAT_acetyltr_2 PF13718.1 ETO27670.1 - 1.1e-49 168.4 0.0 2.1e-49 167.5 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 DUF1726 PF08351.6 ETO27670.1 - 2e-24 85.1 0.0 6.4e-24 83.4 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) Acetyltransf_1 PF00583.19 ETO27670.1 - 0.00043 20.2 0.0 0.0023 17.9 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETO27670.1 - 0.00067 19.7 0.0 0.0019 18.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AAA_22 PF13401.1 ETO27670.1 - 0.0025 17.9 0.1 0.54 10.3 0.0 3.7 3 1 0 3 3 3 1 AAA domain Acetyltransf_3 PF13302.1 ETO27670.1 - 0.0095 16.1 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RNA_pol_Rpb6 PF01192.17 ETO27671.1 - 1.7e-21 75.7 0.4 2.8e-21 75.0 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 NICE-3 PF07406.6 ETO27672.1 - 0.046 13.2 0.1 0.053 13.0 0.1 1.1 1 0 0 1 1 1 0 NICE-3 protein DUF4129 PF13559.1 ETO27672.1 - 0.074 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) NIF PF03031.13 ETO27675.1 - 6.8e-25 87.5 2.4 1.2e-23 83.5 1.5 2.6 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 ETO27675.1 - 2e-07 30.7 0.0 5.2e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 ETO27675.1 - 2.8e-06 27.3 0.1 8.6e-06 25.8 0.1 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain SpoIISA_toxin PF14171.1 ETO27675.1 - 0.024 13.8 2.3 0.062 12.5 1.6 1.6 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system NOA36 PF06524.7 ETO27675.1 - 1 8.5 10.7 2.4 7.3 7.4 1.6 1 0 0 1 1 1 0 NOA36 protein tRNA_bind_2 PF13725.1 ETO27676.1 - 2.7e-16 59.5 0.5 5.1e-16 58.6 0.1 1.7 2 0 0 2 2 2 1 Possible tRNA binding domain HTH_10 PF04967.7 ETO27676.1 - 0.061 12.9 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 HTH DNA binding domain Chromo_shadow PF01393.14 ETO27676.1 - 0.068 13.0 0.6 0.14 12.0 0.4 1.4 1 0 0 1 1 1 0 Chromo shadow domain IATP PF04568.7 ETO27676.1 - 3.8 7.6 9.3 29 4.7 6.5 2.4 1 1 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP PAP_RNA-bind PF04926.10 ETO27677.1 - 0.03 13.8 0.2 0.044 13.3 0.2 1.2 1 0 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain PB1 PF00564.19 ETO27677.1 - 0.044 13.4 0.1 0.083 12.5 0.0 1.5 1 0 0 1 1 1 0 PB1 domain FtsJ PF01728.14 ETO27677.1 - 0.075 13.0 0.2 0.088 12.7 0.1 1.1 1 0 0 1 1 1 0 FtsJ-like methyltransferase HSP70 PF00012.15 ETO27678.1 - 1.6e-63 214.6 5.2 1.2e-62 211.6 3.6 1.9 1 1 0 1 1 1 1 Hsp70 protein Recombinase PF07508.8 ETO27678.1 - 0.0082 16.3 1.9 0.56 10.4 1.3 2.4 1 1 0 1 1 1 1 Recombinase Sial-lect-inser PF09264.5 ETO27678.1 - 0.063 12.5 0.1 0.087 12.1 0.1 1.3 1 0 0 1 1 1 0 Vibrio cholerae sialidase, lectin insertion FtsA PF14450.1 ETO27678.1 - 0.14 12.0 1.5 0.58 10.0 1.0 2.2 1 1 0 1 1 1 0 Cell division protein FtsA WD40 PF00400.27 ETO27679.1 - 2.6e-57 188.7 13.7 2.4e-11 43.0 0.1 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO27679.1 - 1e-05 23.9 0.4 0.042 11.9 0.1 3.6 1 1 2 3 3 3 1 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO27679.1 - 0.00089 19.1 0.4 3.1 7.7 0.0 4.0 3 1 2 5 5 5 2 Domain of unknown function (DUF3601) PQQ_2 PF13360.1 ETO27679.1 - 0.0015 18.0 0.0 0.032 13.6 0.0 2.1 1 1 0 2 2 2 1 PQQ-like domain Nucleoporin_N PF08801.6 ETO27679.1 - 0.027 13.2 8.0 0.24 10.0 0.6 3.5 1 1 3 4 4 4 0 Nup133 N terminal like DUF1914 PF08932.5 ETO27679.1 - 0.09 12.8 6.6 0.62 10.1 0.1 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF1914) PQQ PF01011.16 ETO27679.1 - 0.14 11.7 0.0 5.8 6.6 0.0 3.0 3 0 0 3 3 3 0 PQQ enzyme repeat WD40 PF00400.27 ETO27680.1 - 1.9e-64 211.3 7.6 5.4e-10 38.7 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO27680.1 - 3.1e-07 28.9 0.2 0.34 8.9 0.0 4.3 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO27680.1 - 1.5e-06 26.7 1.3 0.058 11.6 0.0 3.0 1 1 2 3 3 3 2 Cytochrome D1 heme domain Mid2 PF04478.7 ETO27680.1 - 2.5e-05 23.7 9.3 0.22 10.9 0.0 4.9 2 1 3 5 5 5 3 Mid2 like cell wall stress sensor Nucleoporin_N PF08801.6 ETO27680.1 - 0.00088 18.1 13.2 0.15 10.7 4.1 3.8 1 1 1 2 2 2 2 Nup133 N terminal like Nbas_N PF15492.1 ETO27680.1 - 0.0018 17.4 0.4 1.1 8.3 0.0 3.1 1 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 ETO27680.1 - 0.008 15.6 0.0 0.066 12.6 0.0 2.1 1 1 0 1 1 1 1 PQQ-like domain PD40 PF07676.7 ETO27680.1 - 0.018 14.6 3.1 12 5.6 0.0 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF727 PF05303.7 ETO27680.1 - 0.12 12.1 0.0 11 5.9 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF727) PLD_C PF12357.3 ETO27680.1 - 0.13 11.8 0.1 1.7e+02 1.8 0.0 4.4 4 1 0 5 5 5 0 Phospholipase D C terminal WD40 PF00400.27 ETO27681.1 - 8.2e-19 66.7 8.5 1.5e-05 24.6 0.0 5.2 5 1 0 5 5 5 4 WD domain, G-beta repeat IKI3 PF04762.7 ETO27681.1 - 0.044 11.5 0.1 0.078 10.7 0.1 1.5 2 0 0 2 2 2 0 IKI3 family PASTA PF03793.14 ETO27682.1 - 0.06 12.9 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 PASTA domain Metallophos_C PF14008.1 ETO27682.1 - 0.062 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Iron/zinc purple acid phosphatase-like protein C DUF4097 PF13349.1 ETO27682.1 - 0.16 11.5 1.0 0.21 11.0 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) DUF912 PF06024.7 ETO27685.1 - 0.0012 18.7 3.5 0.0012 18.7 2.5 4.5 4 1 0 4 4 4 1 Nucleopolyhedrovirus protein of unknown function (DUF912) OATP PF03137.15 ETO27685.1 - 0.0059 14.7 0.5 0.0059 14.7 0.3 1.9 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Pex14_N PF04695.8 ETO27685.1 - 0.015 15.3 2.0 0.015 15.3 1.4 4.7 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HCO3_cotransp PF00955.16 ETO27685.1 - 0.33 9.5 1.9 0.75 8.3 1.3 1.5 1 0 0 1 1 1 0 HCO3- transporter family Spt5_N PF11942.3 ETO27686.1 - 0.032 14.8 12.1 0.032 14.8 8.4 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Sigma70_ner PF04546.8 ETO27686.1 - 1.2 8.7 19.9 1.5 8.3 4.9 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region TFIIH_BTF_p62_N PF08567.6 ETO27687.1 - 0.082 12.5 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain Ribosomal_60s PF00428.14 ETO27688.1 - 0.0036 17.6 6.7 0.0079 16.5 4.6 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2890 PF11081.3 ETO27688.1 - 0.0098 15.9 2.4 0.013 15.6 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2890) HSP90 PF00183.13 ETO27688.1 - 0.019 13.3 5.9 0.027 12.8 4.1 1.1 1 0 0 1 1 1 0 Hsp90 protein CDC45 PF02724.9 ETO27688.1 - 0.063 11.3 2.8 0.076 11.0 2.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 ETO27688.1 - 0.078 12.4 11.2 0.061 12.8 6.8 1.5 2 0 0 2 2 2 0 Nucleoplasmin Sigma70_ner PF04546.8 ETO27688.1 - 0.13 11.8 6.3 0.2 11.2 4.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region TRAP_alpha PF03896.11 ETO27688.1 - 0.15 11.0 4.9 0.21 10.5 3.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit BSP_II PF05432.6 ETO27688.1 - 0.26 10.5 16.2 0.37 10.0 11.3 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Pox_RNA_Pol_19 PF05320.7 ETO27688.1 - 0.28 10.9 7.2 0.66 9.7 5.0 1.6 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Daxx PF03344.10 ETO27688.1 - 0.31 9.4 12.1 0.42 9.0 8.4 1.1 1 0 0 1 1 1 0 Daxx Family FAM176 PF14851.1 ETO27688.1 - 0.33 10.6 4.2 0.55 9.8 2.9 1.3 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.1 ETO27688.1 - 0.41 10.9 5.4 0.72 10.2 3.8 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RNA_pol_3_Rpc31 PF11705.3 ETO27688.1 - 0.57 10.0 10.2 0.83 9.5 7.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.7 ETO27688.1 - 0.79 8.9 10.3 1.1 8.4 7.2 1.1 1 0 0 1 1 1 0 NOA36 protein Myc_N PF01056.13 ETO27688.1 - 0.83 8.7 9.2 1.2 8.2 6.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF2457 PF10446.4 ETO27688.1 - 0.94 8.1 13.2 1.4 7.6 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) VID27 PF08553.5 ETO27688.1 - 2.5 6.2 10.3 3.3 5.7 7.1 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Adeno_terminal PF02459.10 ETO27688.1 - 2.7 6.0 5.0 4 5.5 3.5 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Paf1 PF03985.8 ETO27688.1 - 3.3 6.3 10.1 4.7 5.8 7.0 1.2 1 0 0 1 1 1 0 Paf1 CENP-B_dimeris PF09026.5 ETO27688.1 - 6.4 7.0 16.8 12 6.2 11.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ashwin PF15323.1 ETO27689.1 - 1.2 9.0 5.9 1.8 8.5 4.1 1.2 1 0 0 1 1 1 0 Developmental protein ERM PF00769.14 ETO27690.1 - 0.0011 18.5 8.5 0.0019 17.7 5.9 1.4 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Spc7 PF08317.6 ETO27690.1 - 0.0024 16.6 7.7 0.0045 15.6 5.4 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein Cluap1 PF10234.4 ETO27690.1 - 0.0061 15.7 8.1 0.012 14.8 5.6 1.4 1 0 0 1 1 1 1 Clusterin-associated protein-1 Chorismate_bind PF00425.13 ETO27690.1 - 0.024 13.9 1.8 0.04 13.2 1.3 1.4 1 0 0 1 1 1 0 chorismate binding enzyme ATP-synt_G PF04718.10 ETO27690.1 - 0.26 11.9 1.1 3.7 8.2 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial ATP synthase g subunit Reo_sigmaC PF04582.7 ETO27690.1 - 0.29 10.2 10.1 0.52 9.4 7.0 1.3 1 1 0 1 1 1 0 Reovirus sigma C capsid protein V_ATPase_I PF01496.14 ETO27690.1 - 0.41 8.4 5.7 0.54 8.0 4.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SIP1 PF04938.7 ETO27690.1 - 0.9 8.8 13.0 0.094 12.0 3.3 2.1 1 1 1 2 2 2 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) PE PF00934.15 ETO27690.1 - 0.99 9.5 3.8 0.8 9.8 0.3 2.5 2 1 1 3 3 3 0 PE family APG6 PF04111.7 ETO27690.1 - 2.7 6.9 16.6 7.5 5.5 11.3 1.9 1 1 1 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 ETO27690.1 - 4.6 6.7 20.4 0.024 14.2 8.0 1.7 3 0 0 3 3 3 0 IncA protein Metallophos PF00149.23 ETO27691.1 - 2.9e-08 33.3 9.9 3.7e-06 26.4 6.9 3.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 ETO27691.1 - 6.1e-07 29.4 0.2 1.2e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.20 ETO27692.1 - 1.3e-35 122.8 0.9 1.3e-35 122.8 0.6 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO27692.1 - 1.1e-25 90.2 1.3 1.1e-25 90.2 0.9 2.0 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase PF00069.20 ETO27693.1 - 4.3e-14 52.2 0.0 5.8e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PseudoU_synth_2 PF00849.17 ETO27695.1 - 7.9e-09 35.5 1.0 1.1e-08 35.1 0.7 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase PseudoU_synth_2 PF00849.17 ETO27696.1 - 1.2e-19 70.6 0.1 6.3e-19 68.3 0.0 2.2 2 1 0 2 2 2 1 RNA pseudouridylate synthase TadE PF07811.7 ETO27696.1 - 4.4 7.2 6.4 7.5 6.5 4.5 1.3 1 0 0 1 1 1 0 TadE-like protein CENP-C_C PF11699.3 ETO27698.1 - 3e-07 30.3 0.2 6.1e-07 29.3 0.2 1.5 1 1 0 1 1 1 1 Mif2/CENP-C like TMEM101 PF15111.1 ETO27700.1 - 0.016 14.5 2.4 0.08 12.2 0.7 2.0 1 1 0 2 2 2 0 TMEM101 protein family Prefoldin_2 PF01920.15 ETO27702.1 - 0.013 15.2 1.7 0.016 14.9 0.4 1.7 1 1 0 1 1 1 0 Prefoldin subunit DUF3166 PF11365.3 ETO27702.1 - 0.079 13.4 0.4 0.54 10.7 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3166) Pox_A_type_inc PF04508.7 ETO27702.1 - 0.16 11.8 0.5 0.55 10.1 0.3 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat TMF_TATA_bd PF12325.3 ETO27703.1 - 1.8e-08 34.1 2.0 1.8e-08 34.1 1.4 11.4 4 2 6 11 11 11 2 TATA element modulatory factor 1 TATA binding DivIC PF04977.10 ETO27703.1 - 0.00063 19.1 0.6 0.00063 19.1 0.4 14.8 7 3 5 15 15 15 8 Septum formation initiator Reo_sigmaC PF04582.7 ETO27703.1 - 0.84 8.7 54.2 0.71 9.0 0.7 7.2 3 2 3 7 7 7 0 Reovirus sigma C capsid protein PT PF04886.7 ETO27704.1 - 2.4 7.5 21.7 1.5e+04 -4.7 15.0 4.2 1 1 0 1 1 1 0 PT repeat TSP_1 PF00090.14 ETO27705.1 - 2.8e-05 24.1 8.5 2.8e-05 24.1 5.9 2.5 1 1 1 2 2 2 1 Thrombospondin type 1 domain zf-RING_5 PF14634.1 ETO27706.1 - 7.8e-07 28.7 1.7 7.8e-07 28.7 1.2 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 ETO27706.1 - 5.2e-05 22.9 6.1 0.00011 21.9 3.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 ETO27706.1 - 0.00018 21.0 4.4 0.0006 19.4 1.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO27706.1 - 0.00069 19.5 5.2 0.00069 19.5 3.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO27706.1 - 0.0074 15.9 3.3 0.0074 15.9 2.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) GATA PF00320.22 ETO27706.1 - 0.065 12.5 0.8 3.5 7.0 0.1 2.7 2 0 0 2 2 2 0 GATA zinc finger zf-C3HC4_4 PF15227.1 ETO27706.1 - 0.07 13.0 3.0 0.23 11.3 2.1 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 ETO27706.1 - 0.074 12.7 0.8 0.2 11.4 0.6 1.8 1 0 0 1 1 1 0 RING-type zinc-finger TPMT PF05724.6 ETO27708.1 - 5.7e-18 65.1 0.2 1e-11 44.7 0.0 3.1 3 0 0 3 3 3 2 Thiopurine S-methyltransferase (TPMT) Mucin PF01456.12 ETO27708.1 - 0.2 11.4 4.2 0.086 12.6 1.3 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF913 PF06025.7 ETO27709.1 - 0.0022 16.8 1.6 0.0028 16.4 1.1 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) Vmethyltransf_C PF08456.5 ETO27710.1 - 0.022 14.2 2.1 0.05 13.0 1.5 1.6 1 0 0 1 1 1 0 Viral methyltransferase C-terminal PIRT PF15099.1 ETO27710.1 - 0.77 8.9 11.6 1.5 8.0 0.1 3.9 4 0 0 4 4 4 0 Phosphoinositide-interacting protein family WD40 PF00400.27 ETO27711.1 - 5.8e-63 206.6 8.5 9.4e-13 47.5 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO27711.1 - 3.6e-09 35.3 9.3 0.053 11.6 0.2 4.7 1 1 2 4 4 4 4 Nucleoporin Nup120/160 PD40 PF07676.7 ETO27711.1 - 1.3e-07 31.1 5.0 2 8.1 0.1 5.9 6 0 0 6 6 6 3 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO27711.1 - 2.6e-07 30.3 0.8 8.2e-05 22.1 0.2 3.1 2 1 1 3 3 3 1 PQQ-like domain DPPIV_N PF00930.16 ETO27711.1 - 8.7e-05 21.2 0.2 0.096 11.2 0.0 3.4 1 1 2 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Cytochrom_D1 PF02239.11 ETO27711.1 - 0.00023 19.5 1.6 0.53 8.5 0.0 3.5 1 1 4 5 5 5 3 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO27711.1 - 0.00032 19.8 2.2 10 5.1 0.0 5.0 1 1 5 6 6 6 1 Neuroblastoma-amplified sequence, N terminal Resistin PF06954.6 ETO27711.1 - 0.0037 17.4 0.1 32 4.8 0.0 4.5 4 2 0 5 5 5 0 Resistin DUF4073 PF13285.1 ETO27711.1 - 0.1 12.0 0.4 4 6.8 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4073) Proteasome_A_N PF10584.4 ETO27711.1 - 3.6 7.0 12.1 9.5 5.6 0.0 4.6 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature G-alpha PF00503.15 ETO27712.1 - 6.2e-43 146.9 17.1 1.8e-42 145.4 11.8 1.8 1 1 0 1 1 1 1 G-protein alpha subunit VWA_2 PF13519.1 ETO27713.1 - 8.3e-09 35.7 0.0 2.2e-08 34.4 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain SBP_bac_8 PF13416.1 ETO27713.1 - 0.00085 19.1 0.7 0.0024 17.6 0.0 2.0 2 1 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.1 ETO27713.1 - 0.0041 16.7 0.0 0.0093 15.6 0.0 1.6 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein CRAL_TRIO PF00650.15 ETO27715.1 - 2.7e-08 33.4 0.6 3.7e-08 33.0 0.4 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain Tombus_P33 PF08500.5 ETO27715.1 - 0.025 14.3 0.1 0.032 13.9 0.1 1.3 1 1 0 1 1 1 0 Tombusvirus p33 Ribosomal_L6 PF00347.18 ETO27716.1 - 0.063 13.7 0.7 2.1 8.9 0.0 2.6 2 1 0 2 2 2 0 Ribosomal protein L6 Fez1 PF06818.10 ETO27717.1 - 0.074 13.0 14.8 0.13 12.3 10.2 1.3 1 0 0 1 1 1 0 Fez1 DUF3450 PF11932.3 ETO27717.1 - 0.39 9.9 7.5 0.16 11.2 3.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Mnd1 PF03962.10 ETO27717.1 - 1.3 8.6 13.8 2.4 7.7 9.6 1.4 1 0 0 1 1 1 0 Mnd1 family DUF3435 PF11917.3 ETO27717.1 - 1.3 7.6 12.2 1.6 7.3 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) FadA PF09403.5 ETO27717.1 - 1.4 8.9 10.7 3 7.8 7.4 1.6 1 0 0 1 1 1 0 Adhesion protein FadA V_ATPase_I PF01496.14 ETO27717.1 - 1.6 6.4 6.2 1.9 6.2 4.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OmpH PF03938.9 ETO27717.1 - 4.8 7.0 10.6 8 6.3 7.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) APG6 PF04111.7 ETO27717.1 - 5.3 5.9 14.1 8 5.4 9.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Neur_chan_memb PF02932.11 ETO27718.1 - 5.9 6.7 12.3 7.3 6.4 8.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF766 PF05571.7 ETO27719.1 - 0.053 12.7 1.0 0.072 12.3 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF766) SAND PF01342.16 ETO27720.1 - 1.7 8.4 8.8 9.7 5.9 1.9 2.6 1 1 1 2 2 2 0 SAND domain Geminin PF07412.7 ETO27721.1 - 0.00036 20.2 6.3 0.00081 19.1 4.4 1.6 1 0 0 1 1 1 1 Geminin zf-TRAF PF02176.13 ETO27721.1 - 0.00044 20.5 5.4 0.00044 20.5 3.8 2.7 2 0 0 2 2 2 1 TRAF-type zinc finger DP PF08781.5 ETO27721.1 - 0.016 14.8 4.6 0.036 13.7 3.2 1.6 1 0 0 1 1 1 0 Transcription factor DP DUF641 PF04859.7 ETO27721.1 - 0.13 11.9 7.3 2.5 7.8 3.6 2.3 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Tnp_P_element PF12017.3 ETO27721.1 - 0.22 10.7 5.9 0.25 10.5 2.6 1.9 2 0 0 2 2 2 0 Transposase protein Ax_dynein_light PF10211.4 ETO27721.1 - 0.34 10.7 11.4 2.6 7.8 0.2 2.4 2 0 0 2 2 2 0 Axonemal dynein light chain Bap31 PF05529.7 ETO27721.1 - 0.94 8.8 12.3 0.088 12.2 5.1 1.7 2 1 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF3338 PF11819.3 ETO27721.1 - 1.4 8.3 9.7 8.4 5.8 3.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3338) PhoU PF01895.14 ETO27721.1 - 3.6 8.1 6.9 1.2 9.6 0.7 2.6 3 0 0 3 3 3 0 PhoU domain Lge1 PF11488.3 ETO27721.1 - 9.8 6.4 10.3 2.4 8.4 1.2 3.4 3 1 1 4 4 4 0 Transcriptional regulatory protein LGE1 Secretin_N_2 PF07655.8 ETO27722.1 - 0.0046 17.3 13.5 0.0046 17.3 9.4 2.6 3 0 0 3 3 3 1 Secretin N-terminal domain DUF912 PF06024.7 ETO27722.1 - 0.0084 16.1 6.6 0.12 12.4 3.6 2.6 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3474 PF11960.3 ETO27722.1 - 0.19 11.7 2.1 4.2 7.3 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3474) Ank_4 PF13637.1 ETO27723.1 - 1.8e-20 72.9 0.3 6.4e-06 26.5 0.1 4.2 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO27723.1 - 9.2e-20 70.7 0.1 1.1e-08 35.3 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO27723.1 - 2.2e-17 62.6 0.1 0.0001 22.4 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 ETO27723.1 - 2e-14 52.5 0.1 0.026 14.3 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 ETO27723.1 - 9.4e-11 40.8 0.1 0.21 11.9 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Rep_fac_C PF08542.6 ETO27723.1 - 0.035 14.0 0.0 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Replication factor C C-terminal domain ABC_tran PF00005.22 ETO27725.1 - 2.6e-13 50.4 0.0 6.1e-13 49.2 0.0 1.5 1 1 0 1 1 1 1 ABC transporter MobB PF03205.9 ETO27725.1 - 0.0027 17.4 0.0 0.0092 15.6 0.0 1.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Ctr PF04145.10 ETO27726.1 - 0.015 15.3 0.4 0.42 10.6 0.0 2.1 1 1 1 2 2 2 0 Ctr copper transporter family CCSMST1 PF15013.1 ETO27726.1 - 0.028 14.3 0.2 0.17 11.8 0.1 2.1 1 1 1 2 2 2 0 CCSMST1 family DAGK_acc PF00609.14 ETO27726.1 - 0.043 13.9 2.5 0.11 12.6 1.7 1.7 1 1 0 1 1 1 0 Diacylglycerol kinase accessory domain DUF3671 PF12420.3 ETO27726.1 - 0.072 13.0 3.1 0.13 12.2 0.3 2.2 2 1 0 2 2 2 0 Protein of unknown function DUF2031 PF09592.5 ETO27726.1 - 0.18 10.9 4.2 0.033 13.3 0.6 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2031) DUF2951 PF11166.3 ETO27726.1 - 1.6 8.6 6.9 0.47 10.3 2.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Macoilin PF09726.4 ETO27726.1 - 2.4 6.3 10.0 3.1 5.9 6.9 1.1 1 0 0 1 1 1 0 Transmembrane protein PH PF00169.24 ETO27728.1 - 0.00016 21.8 0.1 0.0004 20.5 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF1777 PF08648.7 ETO27729.1 - 0.00041 20.1 19.0 0.00053 19.7 13.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 ETO27729.1 - 9.3 4.5 18.6 11 4.2 12.9 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PspB PF06667.7 ETO27731.1 - 0.014 15.3 0.0 0.037 13.9 0.0 1.7 1 0 0 1 1 1 0 Phage shock protein B Dehyd-heme_bind PF09098.5 ETO27731.1 - 0.026 13.9 0.1 0.038 13.4 0.1 1.4 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding CPSase_L_D3 PF02787.14 ETO27731.1 - 0.067 12.9 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Cohesin PF00963.13 ETO27731.1 - 0.11 12.3 1.8 0.96 9.3 0.2 2.1 2 0 0 2 2 2 0 Cohesin domain RasGEF PF00617.14 ETO27732.1 - 1.5e-12 47.6 0.6 2.3e-12 47.0 0.4 1.2 1 0 0 1 1 1 1 RasGEF domain MSP7_C PF12948.2 ETO27732.1 - 0.029 14.6 4.9 0.44 10.7 1.1 2.2 2 0 0 2 2 2 0 MSP7-like protein C-terminal domain IRF PF00605.12 ETO27732.1 - 0.27 11.0 2.8 4.1 7.2 0.1 2.1 1 1 1 2 2 2 0 Interferon regulatory factor transcription factor PAZ PF02170.17 ETO27732.1 - 1.3 8.3 4.6 1.7 7.9 2.7 1.5 1 1 1 2 2 2 0 PAZ domain RasGEF PF00617.14 ETO27733.1 - 5.9e-19 68.5 1.1 5.9e-19 68.5 0.8 1.8 2 0 0 2 2 2 1 RasGEF domain Guanylate_cyc PF00211.15 ETO27734.1 - 6.1e-05 22.4 0.0 8.7e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain TMEM154 PF15102.1 ETO27734.1 - 0.093 12.4 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF2681 PF10883.3 ETO27734.1 - 4.5 7.5 8.8 2.2 8.5 1.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Nop14 PF04147.7 ETO27735.1 - 5.2e-05 21.4 36.2 9.4e-05 20.5 25.1 1.3 1 0 0 1 1 1 1 Nop14-like family CENP-T PF15511.1 ETO27735.1 - 0.0011 18.3 20.6 0.0016 17.7 14.3 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T EF_assoc_2 PF08356.7 ETO27735.1 - 0.011 15.4 0.1 0.056 13.1 0.0 2.2 2 0 0 2 2 2 0 EF hand associated Phage_fiber_C PF06820.7 ETO27735.1 - 0.03 14.4 0.0 0.075 13.1 0.0 1.6 1 0 0 1 1 1 0 Putative prophage tail fibre C-terminus TFIIF_alpha PF05793.7 ETO27735.1 - 0.04 12.2 42.0 0.065 11.5 29.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Raftlin PF15250.1 ETO27735.1 - 0.042 12.3 9.7 0.078 11.4 6.8 1.3 1 0 0 1 1 1 0 Raftlin BUD22 PF09073.5 ETO27735.1 - 0.056 12.5 34.3 0.087 11.8 23.7 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.9 ETO27735.1 - 0.07 11.1 34.1 0.11 10.4 23.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 ETO27735.1 - 0.089 11.2 35.9 0.14 10.6 24.9 1.2 1 0 0 1 1 1 0 Daxx Family SprA-related PF12118.3 ETO27735.1 - 0.28 10.4 22.4 0.45 9.8 15.5 1.2 1 0 0 1 1 1 0 SprA-related family Hid1 PF12722.2 ETO27735.1 - 0.3 8.7 16.7 0.56 7.8 11.6 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4045 PF13254.1 ETO27735.1 - 0.81 8.8 18.8 1.3 8.2 13.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Astro_capsid PF03115.9 ETO27735.1 - 3.7 5.6 10.1 5.1 5.2 7.0 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF2201_N PF13203.1 ETO27735.1 - 4.6 6.3 12.4 8.2 5.4 8.6 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain Zip PF02535.17 ETO27735.1 - 7.6 5.4 7.3 15 4.5 5.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Ycf1 PF05758.7 ETO27735.1 - 8.2 3.9 20.8 13 3.3 14.4 1.3 1 0 0 1 1 1 0 Ycf1 DDHD PF02862.12 ETO27735.1 - 8.9 6.0 15.5 29 4.3 10.8 1.8 1 0 0 1 1 1 0 DDHD domain Mg_chelatase PF01078.16 ETO27736.1 - 0.0014 17.8 0.5 0.0024 17.0 0.3 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA PF00004.24 ETO27736.1 - 0.0079 16.4 0.4 0.0079 16.4 0.3 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FAM176 PF14851.1 ETO27736.1 - 0.1 12.2 0.7 0.14 11.8 0.5 1.2 1 0 0 1 1 1 0 FAM176 family AAA PF00004.24 ETO27737.1 - 7.5e-29 100.5 0.1 1.3e-28 99.8 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 ETO27737.1 - 0.00081 19.2 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain PELOTA_1 PF15608.1 ETO27737.1 - 0.013 15.2 0.1 0.042 13.6 0.1 1.8 1 0 0 1 1 1 0 PELOTA RNA binding domain DUF390 PF04094.9 ETO27737.1 - 0.16 9.9 6.7 0.22 9.5 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) Costars PF14705.1 ETO27738.1 - 1.4e-29 101.9 0.3 1.7e-29 101.6 0.2 1.1 1 0 0 1 1 1 1 Costars WD40 PF00400.27 ETO27739.1 - 6.9e-68 222.2 13.3 2.8e-11 42.8 0.0 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO27739.1 - 2.4e-09 36.9 3.4 3.4e-06 27.0 0.0 4.9 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.20 ETO27739.1 - 2.6e-06 26.8 1.8 0.0012 18.3 0.0 3.8 4 0 0 4 4 4 1 Kelch motif Nup160 PF11715.3 ETO27739.1 - 4.7e-06 25.0 7.7 0.42 8.6 0.9 4.8 1 1 3 4 4 4 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO27739.1 - 5.2e-05 22.8 0.5 0.017 14.5 0.1 2.4 1 1 1 2 2 2 2 PQQ-like domain BBS2_Mid PF14783.1 ETO27739.1 - 0.00011 21.9 1.6 0.045 13.5 0.1 3.6 3 2 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Kelch_4 PF13418.1 ETO27739.1 - 0.001 18.8 8.2 0.0011 18.7 0.1 4.4 4 1 1 5 5 5 1 Galactose oxidase, central domain Cytochrom_D1 PF02239.11 ETO27739.1 - 0.0067 14.7 2.0 2.8 6.1 0.0 3.0 1 1 1 3 3 3 2 Cytochrome D1 heme domain Kelch_5 PF13854.1 ETO27739.1 - 0.097 12.6 3.5 0.15 12.0 0.1 3.1 5 0 0 5 5 5 0 Kelch motif Pkinase PF00069.20 ETO27740.1 - 0.0064 15.6 0.1 0.02 14.0 0.0 1.8 1 1 1 2 2 2 1 Protein kinase domain Protocadherin PF08374.6 ETO27740.1 - 0.13 11.8 2.7 0.18 11.4 1.9 1.2 1 0 0 1 1 1 0 Protocadherin STN1_2 PF09170.5 ETO27740.1 - 0.13 11.9 3.7 0.24 11.1 2.6 1.3 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 DUF2360 PF10152.4 ETO27740.1 - 0.16 12.2 3.8 0.22 11.7 2.6 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Sec62 PF03839.11 ETO27740.1 - 1.8 7.9 7.8 2.6 7.4 5.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Pkinase PF00069.20 ETO27741.1 - 7.3e-13 48.2 0.0 8.6e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 ETO27741.1 - 2.9e-07 29.7 0.0 3.1e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 ETO27741.1 - 5.3e-06 25.6 0.0 6.2e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PI3Ka PF00613.15 ETO27744.1 - 1e-42 145.4 0.9 1.9e-42 144.5 0.6 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 ETO27744.1 - 1.5e-35 122.8 0.4 1.5e-35 122.8 0.3 2.5 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 ETO27744.1 - 0.0037 17.0 0.0 0.0096 15.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF2392 PF10288.4 ETO27746.1 - 0.13 12.6 1.2 0.27 11.5 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) LRR_1 PF00560.28 ETO27747.1 - 0.87 9.8 9.3 6.5 7.2 0.1 5.5 4 1 0 4 4 4 0 Leucine Rich Repeat PARP PF00644.15 ETO27749.1 - 2.6e-24 85.7 2.0 7.6e-18 64.6 0.0 2.7 3 1 0 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 ETO27749.1 - 4.5e-12 45.7 0.7 7.3e-12 45.1 0.5 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain Pkinase PF00069.20 ETO27751.1 - 0.00024 20.3 0.2 0.0003 20.0 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO27751.1 - 0.008 15.2 0.2 0.01 14.9 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Cu-oxidase_4 PF02578.10 ETO27752.1 - 0.14 11.2 0.7 0.41 9.6 0.0 2.0 2 0 0 2 2 2 0 Multi-copper polyphenol oxidoreductase laccase Rap_GAP PF02145.10 ETO27753.1 - 1.2e-12 47.6 0.0 1.8e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP Fanconi_C PF02106.10 ETO27753.1 - 0.09 11.1 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 Fanconi anaemia group C protein HEAT PF02985.17 ETO27755.1 - 3.5e-12 45.3 1.3 0.035 14.1 0.0 5.6 5 0 0 5 5 5 3 HEAT repeat Kinase-like PF14531.1 ETO27755.1 - 2.9e-06 26.4 0.0 4.8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Adaptin_N PF01602.15 ETO27755.1 - 4.6e-05 21.9 2.4 0.04 12.2 0.1 2.1 1 1 1 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.1 ETO27755.1 - 0.0018 18.5 0.0 0.3 11.3 0.0 3.0 1 1 1 2 2 2 2 HEAT repeats Pkinase PF00069.20 ETO27755.1 - 0.003 16.7 0.0 0.019 14.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain HEAT_EZ PF13513.1 ETO27755.1 - 0.0054 17.1 0.0 1.2 9.6 0.0 3.7 2 1 1 3 3 3 1 HEAT-like repeat Pkinase_Tyr PF07714.12 ETO27755.1 - 0.018 14.1 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase SNARE PF05739.14 ETO27756.1 - 0.0048 16.5 0.0 0.009 15.6 0.0 1.5 1 0 0 1 1 1 1 SNARE domain IFRD PF05004.8 ETO27758.1 - 0.055 12.5 0.8 0.065 12.3 0.5 1.1 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) IcmL PF11393.3 ETO27758.1 - 0.58 10.1 4.0 9 6.2 0.6 2.0 1 1 1 2 2 2 0 Macrophage killing protein with similarity to conjugation protein Sod_Fe_C PF02777.13 ETO27759.1 - 9.3e-22 76.8 2.0 9.7e-22 76.8 0.4 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 ETO27759.1 - 5.6e-11 42.5 0.7 5.6e-11 42.5 0.5 1.9 2 1 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DSPc PF00782.15 ETO27760.1 - 1.6e-16 60.1 0.9 4.5e-16 58.6 0.6 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 ETO27760.1 - 0.00011 21.6 1.2 0.0002 20.8 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 ETO27760.1 - 0.055 13.5 0.5 0.29 11.1 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 ETO27760.1 - 0.076 13.2 0.2 0.22 11.7 0.0 1.9 1 1 1 2 2 2 0 Tyrosine phosphatase family DUF3290 PF11694.3 ETO27760.1 - 0.32 10.7 3.4 0.35 10.5 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) FA_hydroxylase PF04116.8 ETO27761.1 - 2.8e-12 47.0 20.3 5.7e-12 46.0 14.1 1.5 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily 5_3_exonuc PF01367.15 ETO27762.1 - 0.069 13.3 0.2 11 6.3 0.0 2.4 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Peptidase_S9_N PF02897.10 ETO27763.1 - 1.6e-40 138.9 3.1 2e-40 138.6 2.1 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF2430 PF10353.4 ETO27763.1 - 0.082 13.0 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2430) DUF1336 PF07059.7 ETO27764.1 - 0.049 13.0 0.1 0.087 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1336) IBR PF01485.16 ETO27767.1 - 0.028 14.3 4.2 0.049 13.4 2.9 1.4 1 0 0 1 1 1 0 IBR domain HEAT PF02985.17 ETO27768.1 - 3.6e-07 29.6 0.7 0.032 14.3 0.2 3.5 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.1 ETO27768.1 - 0.00022 21.4 0.7 0.0018 18.5 0.2 2.0 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 ETO27768.1 - 0.0019 18.6 0.2 0.027 14.9 0.0 2.4 2 0 0 2 2 2 1 HEAT-like repeat CLASP_N PF12348.3 ETO27768.1 - 0.0074 15.6 0.0 0.0089 15.4 0.0 1.2 1 0 0 1 1 1 1 CLASP N terminal Kelch_1 PF01344.20 ETO27769.1 - 0.0051 16.3 2.7 0.061 12.8 0.2 3.1 3 1 1 4 4 4 1 Kelch motif Kelch_2 PF07646.10 ETO27769.1 - 0.18 11.6 0.7 1.9 8.3 0.0 2.9 2 0 0 2 2 2 0 Kelch motif WD40 PF00400.27 ETO27770.1 - 1.3e-82 268.9 19.6 1.3e-12 47.0 0.1 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO27770.1 - 8.9e-10 38.3 5.3 5.2e-05 23.2 0.1 4.4 4 0 0 4 4 4 2 Kelch motif Nup160 PF11715.3 ETO27770.1 - 3.7e-07 28.6 11.7 0.03 12.4 0.1 5.1 1 1 4 5 5 5 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO27770.1 - 8.7e-07 27.5 3.6 0.0073 14.6 0.1 2.9 3 0 0 3 3 3 2 Cytochrome D1 heme domain DUF1258 PF06869.7 ETO27770.1 - 0.0021 17.1 4.0 0.17 10.9 0.0 3.8 2 1 2 4 4 4 1 Protein of unknown function (DUF1258) Kelch_4 PF13418.1 ETO27770.1 - 0.0038 16.9 1.5 0.019 14.7 0.0 3.1 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO27770.1 - 0.012 15.5 4.3 1.7 8.6 0.8 3.6 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.10 ETO27770.1 - 0.019 14.7 2.4 3.6 7.5 0.0 3.3 3 0 0 3 3 2 0 Kelch motif Resistin PF06954.6 ETO27770.1 - 0.019 15.2 0.9 18 5.6 0.0 4.4 4 1 1 5 5 5 0 Resistin PTEN_C2 PF10409.4 ETO27770.1 - 0.024 14.3 0.7 0.069 12.8 0.0 2.1 2 0 0 2 2 2 0 C2 domain of PTEN tumour-suppressor protein Kelch_1 PF01344.20 ETO27770.1 - 0.038 13.5 11.0 0.18 11.3 0.2 3.3 3 0 0 3 3 3 0 Kelch motif DUF1921 PF09081.5 ETO27770.1 - 0.044 13.7 0.1 0.45 10.5 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1921) Kelch_3 PF13415.1 ETO27770.1 - 0.23 11.6 3.1 14 6.0 0.0 3.8 4 0 0 4 4 4 0 Galactose oxidase, central domain zf-RING_2 PF13639.1 ETO27771.1 - 3.7e-07 29.8 3.9 3.7e-07 29.8 2.7 4.0 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.20 ETO27771.1 - 7.1e-07 28.7 4.5 7.1e-07 28.7 3.1 3.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO27771.1 - 8.5e-07 28.6 5.1 8.5e-07 28.6 3.5 3.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-rbx1 PF12678.2 ETO27771.1 - 6.1e-05 23.0 6.3 6.1e-05 23.0 4.4 2.9 1 1 2 3 3 3 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 ETO27771.1 - 0.00059 19.4 3.4 0.00059 19.4 2.3 3.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO27771.1 - 0.00064 19.6 6.1 0.00064 19.6 4.3 4.6 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 ETO27771.1 - 0.00075 19.1 16.0 0.0012 18.4 2.6 3.0 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_6 PF14835.1 ETO27771.1 - 0.034 13.9 0.9 0.12 12.1 0.6 2.0 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF3439 PF11921.3 ETO27771.1 - 0.035 13.8 1.5 0.066 12.9 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) zf-RING_UBOX PF13445.1 ETO27771.1 - 0.09 12.5 5.2 0.36 10.5 0.4 3.3 2 0 0 2 2 2 0 RING-type zinc-finger DUF2634 PF10934.3 ETO27772.1 - 0.018 14.7 0.0 0.043 13.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2634) DUF3377 PF11857.3 ETO27772.1 - 0.068 12.8 0.0 2.5 7.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) DUF308 PF03729.8 ETO27772.1 - 4.2 7.4 7.1 1.8 8.5 2.9 1.8 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) RGS PF00615.14 ETO27773.1 - 3.9e-07 30.1 0.1 9.7e-07 28.9 0.1 1.7 1 1 0 1 1 1 1 Regulator of G protein signaling domain HIN PF02760.10 ETO27773.1 - 0.042 13.2 0.0 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 HIN-200/IF120x domain RRM_1 PF00076.17 ETO27774.1 - 0.028 14.0 0.1 0.45 10.1 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO27774.1 - 0.079 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hus1 PF04005.7 ETO27774.1 - 0.11 11.4 1.8 0.11 11.3 0.4 1.5 1 1 1 2 2 2 0 Hus1-like protein TFIIF_alpha PF05793.7 ETO27774.1 - 3 6.1 20.3 4 5.6 14.1 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FAM176 PF14851.1 ETO27774.1 - 5.7 6.5 9.7 9.5 5.8 4.3 2.0 1 1 1 2 2 2 0 FAM176 family RRM_1 PF00076.17 ETO27775.1 - 3e-14 52.4 0.0 7.6e-13 47.9 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO27775.1 - 6.3e-12 45.3 0.1 3.1e-11 43.0 0.0 2.2 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO27775.1 - 7.4e-10 38.5 0.1 2e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 7tm_1 PF00001.16 ETO27775.1 - 0.0034 16.5 0.6 0.0058 15.8 0.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3357 PF11837.3 ETO27775.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) 7TM_GPCR_Srv PF10323.4 ETO27775.1 - 0.15 11.1 6.2 0.083 12.0 1.5 2.1 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv DNA_mis_repair PF01119.14 ETO27776.1 - 6.4e-24 83.7 0.6 1e-22 79.8 0.4 2.5 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain Rsc14 PF08586.5 ETO27776.1 - 0.031 14.7 1.5 0.089 13.2 0.0 2.5 2 1 1 3 3 3 0 RSC complex, Rsc14/Ldb7 subunit AAA_5 PF07728.9 ETO27777.1 - 0.0076 15.9 0.0 0.031 14.0 0.0 1.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AKNA PF12443.3 ETO27777.1 - 0.015 15.2 0.4 0.032 14.2 0.3 1.6 1 0 0 1 1 1 0 AT-hook-containing transcription factor Hormone_recep PF00104.25 ETO27778.1 - 0.093 11.8 0.1 0.11 11.6 0.1 1.1 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor Lectin_N PF03954.9 ETO27778.1 - 0.21 10.9 1.4 0.35 10.2 1.0 1.5 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain Pex14_N PF04695.8 ETO27779.1 - 0.02 14.9 2.4 0.021 14.8 0.7 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF912 PF06024.7 ETO27779.1 - 4.5 7.3 5.6 1.9 8.5 1.0 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) RIC1 PF07064.8 ETO27780.1 - 0.0089 15.5 0.1 0.013 15.0 0.1 1.2 1 0 0 1 1 1 1 RIC1 CDC50 PF03381.10 ETO27781.1 - 6.3e-08 32.1 1.0 1.2e-07 31.2 0.7 1.4 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family tRNA-synt_1g PF09334.6 ETO27783.1 - 7.8e-09 34.6 3.6 7.8e-09 34.6 0.0 2.5 2 1 1 3 3 3 1 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 ETO27783.1 - 2.5e-08 33.4 0.0 5.9e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1 PF00133.17 ETO27783.1 - 1.9e-07 29.4 0.2 3.7e-07 28.5 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) fn3 PF00041.16 ETO27784.1 - 4.5e-09 36.3 0.0 0.0071 16.4 0.0 4.2 3 0 0 3 3 3 3 Fibronectin type III domain DUF1387 PF07139.6 ETO27785.1 - 0.076 12.6 2.0 0.093 12.3 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) BLVR PF06375.6 ETO27785.1 - 8.7 6.1 8.4 19 5.0 5.9 1.7 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) RNase_Zc3h12a PF11977.3 ETO27786.1 - 4.4e-20 72.0 0.0 9.7e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain EST1_DNA_bind PF10373.4 ETO27786.1 - 3.8e-11 42.7 2.3 1.3e-10 40.9 1.6 1.8 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain zf-C2H2_4 PF13894.1 ETO27787.1 - 0.013 15.7 6.0 0.77 10.2 0.5 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met2 PF12907.2 ETO27787.1 - 0.19 11.7 2.4 1.2 9.2 0.1 2.5 2 0 0 2 2 2 0 Zinc-binding zf-C2H2 PF00096.21 ETO27787.1 - 0.29 11.5 9.5 12 6.4 0.1 3.2 2 1 0 2 2 2 0 Zinc finger, C2H2 type PH_11 PF15413.1 ETO27789.1 - 2.7e-05 24.3 0.0 4.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 ETO27789.1 - 0.00064 19.8 0.8 0.0021 18.2 0.6 1.8 1 1 0 1 1 1 1 PH domain EST1_DNA_bind PF10373.4 ETO27790.1 - 2e-11 43.6 1.9 1.2e-10 41.0 0.0 2.2 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain TPR_11 PF13414.1 ETO27790.1 - 3.4e-07 29.8 0.0 9.1e-07 28.4 0.0 1.7 1 0 0 1 1 1 1 TPR repeat EST1 PF10374.4 ETO27790.1 - 3.1e-06 27.1 3.0 6.9e-06 26.0 2.1 1.6 1 0 0 1 1 1 1 Telomerase activating protein Est1 TPR_17 PF13431.1 ETO27790.1 - 0.00034 20.5 0.1 0.0015 18.5 0.0 2.2 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO27790.1 - 0.033 14.1 0.4 16 5.7 0.0 3.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETO27790.1 - 0.044 13.3 0.0 9.4 6.0 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat ARL2_Bind_BART PF11527.3 ETO27790.1 - 0.052 13.3 4.9 0.3 10.9 0.1 3.1 2 2 1 3 3 3 0 The ARF-like 2 binding protein BART DUF1845 PF08900.6 ETO27790.1 - 0.057 12.6 0.3 0.085 12.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) TcdB_N PF12918.2 ETO27790.1 - 0.32 11.1 2.6 1.6 8.8 0.1 2.8 2 1 0 2 2 2 0 TcdB toxin N-terminal helical domain FliJ PF02050.11 ETO27790.1 - 2.1 8.4 10.0 1.2 9.2 0.8 3.3 3 1 0 3 3 3 0 Flagellar FliJ protein Dna2 PF08696.6 ETO27790.1 - 2.2 7.5 4.8 3.2 7.0 1.0 2.1 1 1 0 2 2 2 0 DNA replication factor Dna2 DUF912 PF06024.7 ETO27791.1 - 0.17 11.9 4.3 0.063 13.3 0.9 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Tim54 PF11711.3 ETO27791.1 - 0.46 9.0 3.5 0.18 10.3 0.8 1.5 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Striatin PF08232.7 ETO27791.1 - 1.5 9.1 8.1 0.22 11.8 2.8 1.7 2 0 0 2 2 2 0 Striatin family CPSF100_C PF13299.1 ETO27791.1 - 3.3 7.8 10.0 12 6.1 3.5 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal E3_binding PF02817.12 ETO27792.1 - 3.4e-15 55.3 0.3 5.3e-15 54.7 0.2 1.3 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl PF00364.17 ETO27792.1 - 5.1e-09 35.6 0.1 0.00075 19.0 0.1 3.0 3 0 0 3 3 3 2 Biotin-requiring enzyme Chorion_2 PF03964.10 ETO27792.1 - 0.061 13.8 2.2 0.074 13.5 0.9 1.7 2 0 0 2 2 2 0 Chorion family 2 Biotin_lipoyl_2 PF13533.1 ETO27792.1 - 0.081 12.5 0.1 0.62 9.7 0.1 2.3 3 0 0 3 3 3 0 Biotin-lipoyl like ThiS PF02597.15 ETO27792.1 - 0.13 12.6 0.0 0.34 11.3 0.0 1.7 2 0 0 2 2 2 0 ThiS family DLD PF14878.1 ETO27794.1 - 0.22 11.6 7.7 0.031 14.3 2.4 1.7 2 0 0 2 2 2 0 Death-like domain of SPT6 AIG1 PF04548.11 ETO27795.1 - 4.4e-17 61.8 0.0 4.4e-17 61.8 0.0 2.7 3 1 1 4 4 4 1 AIG1 family MMR_HSR1 PF01926.18 ETO27795.1 - 2.7e-07 30.5 0.2 1.7e-06 27.9 0.0 2.4 1 1 0 2 2 2 1 50S ribosome-binding GTPase TroA PF01297.12 ETO27795.1 - 0.025 13.8 4.7 0.32 10.1 3.2 2.2 2 0 0 2 2 2 0 Periplasmic solute binding protein family AAA_32 PF13654.1 ETO27795.1 - 0.03 12.9 12.7 0.054 12.1 8.8 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 ETO27795.1 - 0.26 11.5 2.5 0.87 9.8 0.0 2.6 2 0 0 2 2 2 0 ABC transporter Dynamin_N PF00350.18 ETO27795.1 - 1.7 8.4 13.8 1.7e+02 1.8 9.5 3.5 1 1 0 1 1 1 0 Dynamin family Fringe PF02434.11 ETO27796.1 - 1.6e-05 24.3 0.0 2.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Fringe-like PDR_CDR PF06422.7 ETO27796.1 - 0.0028 17.2 0.1 0.0075 15.9 0.1 1.7 2 0 0 2 2 2 1 CDR ABC transporter DUF21 PF01595.15 ETO27797.1 - 4.7e-15 55.3 3.5 6.3e-15 54.9 2.4 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 DUF3754 PF12576.3 ETO27797.1 - 0.38 10.3 3.5 0.96 9.0 2.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3754) TMEMspv1-c74-12 PF11044.3 ETO27797.1 - 4.9 6.7 7.2 2.5 7.7 0.3 2.3 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein CBS PF00571.23 ETO27798.1 - 0.00038 20.1 0.6 0.23 11.2 0.0 3.2 2 1 0 2 2 2 2 CBS domain Gemini_mov PF01708.11 ETO27798.1 - 0.0075 15.8 1.1 0.018 14.5 0.7 1.6 1 0 0 1 1 1 1 Geminivirus putative movement protein FYRC PF05965.9 ETO27799.1 - 0.00016 21.4 0.0 0.00033 20.4 0.0 1.6 1 0 0 1 1 1 1 F/Y rich C-terminus Tim54 PF11711.3 ETO27799.1 - 0.044 12.3 2.2 0.058 11.9 1.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 YqfQ PF14181.1 ETO27799.1 - 3.9 7.4 12.4 5.6 6.9 8.6 1.2 1 0 0 1 1 1 0 YqfQ-like protein Tymo_coat PF00983.13 ETO27800.1 - 0.024 14.3 1.9 0.039 13.6 1.2 1.5 1 1 0 1 1 1 0 Tymovirus coat protein DUF2408 PF10303.4 ETO27800.1 - 0.043 13.9 0.7 0.075 13.1 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Podoplanin PF05808.6 ETO27800.1 - 2.4 7.6 4.7 1.4 8.4 1.6 1.7 1 1 0 1 1 1 0 Podoplanin Ank_2 PF12796.2 ETO27803.1 - 0.00034 20.8 0.1 0.00072 19.8 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO27803.1 - 0.0011 19.3 0.1 0.0027 18.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO27803.1 - 0.0086 16.3 0.4 0.48 10.7 0.1 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO27803.1 - 0.0094 16.1 0.2 0.095 12.9 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.25 ETO27803.1 - 0.015 15.1 0.1 0.12 12.1 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat G-alpha PF00503.15 ETO27804.1 - 2.1e-20 72.7 0.4 2.7e-20 72.4 0.3 1.1 1 0 0 1 1 1 1 G-protein alpha subunit DUF815 PF05673.8 ETO27804.1 - 0.00041 19.3 0.1 0.00056 18.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 ETO27804.1 - 0.003 17.8 0.1 0.0068 16.7 0.1 1.6 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 ETO27804.1 - 0.0045 16.4 0.0 0.0089 15.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 ETO27804.1 - 0.0047 16.9 1.1 0.013 15.5 0.7 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 ETO27804.1 - 0.014 14.8 1.0 0.63 9.4 0.2 2.2 1 1 1 2 2 2 0 AAA-like domain Arch_ATPase PF01637.13 ETO27804.1 - 0.025 14.2 0.1 0.043 13.5 0.1 1.6 1 1 0 1 1 1 0 Archaeal ATPase Zeta_toxin PF06414.7 ETO27804.1 - 0.032 13.3 0.1 0.053 12.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DAP3 PF10236.4 ETO27804.1 - 0.033 13.1 0.5 0.062 12.2 0.1 1.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_33 PF13671.1 ETO27804.1 - 0.038 13.8 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 ETO27804.1 - 0.039 13.8 0.0 0.068 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 ETO27804.1 - 0.071 13.6 0.1 0.16 12.4 0.1 1.6 1 1 0 1 1 1 0 Miro-like protein AAA_17 PF13207.1 ETO27804.1 - 0.14 13.0 0.4 0.25 12.1 0.1 1.8 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.15 ETO27805.1 - 3.7e-26 91.7 9.7 6e-26 91.0 6.7 1.2 1 1 0 1 1 1 1 G-protein alpha subunit DUF815 PF05673.8 ETO27805.1 - 1.7e-05 23.9 0.0 3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 ETO27805.1 - 3.3e-05 23.9 0.0 4.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.7 ETO27805.1 - 0.0013 17.8 0.0 0.0031 16.6 0.0 1.7 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.22 ETO27805.1 - 0.0054 17.0 0.0 0.0078 16.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter NACHT PF05729.7 ETO27805.1 - 0.0063 16.1 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Zeta_toxin PF06414.7 ETO27805.1 - 0.0066 15.5 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin Arch_ATPase PF01637.13 ETO27805.1 - 0.022 14.4 0.3 0.037 13.7 0.2 1.4 1 1 0 1 1 1 0 Archaeal ATPase Miro PF08477.8 ETO27805.1 - 0.029 14.8 0.1 0.074 13.5 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_22 PF13401.1 ETO27805.1 - 0.036 14.1 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 ETO27805.1 - 0.045 13.7 0.0 0.085 12.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain MMR_HSR1 PF01926.18 ETO27805.1 - 0.052 13.5 0.1 0.087 12.7 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 ETO27805.1 - 0.078 12.5 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 ETO27805.1 - 0.079 12.8 0.0 0.14 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain WD40 PF00400.27 ETO27807.1 - 1.2e-15 56.6 13.0 1.4e-08 34.2 0.1 5.3 5 1 0 5 5 5 4 WD domain, G-beta repeat Metallophos PF00149.23 ETO27808.1 - 2.9e-06 26.8 0.0 6.3e-06 25.7 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PUB PF09409.5 ETO27809.1 - 9.5e-07 28.4 0.0 3.1e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 PUB domain Prophage_tail PF06605.6 ETO27810.1 - 0.051 12.4 0.1 0.11 11.4 0.1 1.5 1 1 0 1 1 1 0 Prophage endopeptidase tail Citrate_ly_lig PF08218.6 ETO27810.1 - 0.073 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain UME PF08064.8 ETO27810.1 - 0.14 12.1 1.0 0.5 10.3 0.4 1.9 1 1 1 2 2 2 0 UME (NUC010) domain Sec7 PF01369.15 ETO27811.1 - 3e-39 134.6 3.6 5.9e-39 133.7 2.5 1.5 1 0 0 1 1 1 1 Sec7 domain DUF1981 PF09324.5 ETO27811.1 - 3.7e-25 87.2 2.1 7.7e-25 86.2 0.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) PapD-like PF14874.1 ETO27812.1 - 0.021 14.7 1.1 4 7.4 0.2 3.0 3 0 0 3 3 3 0 Flagellar-associated PapD-like IBN_N PF03810.14 ETO27813.1 - 4.2e-08 32.9 0.3 1.1e-07 31.6 0.2 1.7 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 ETO27813.1 - 0.00021 21.5 0.2 0.03 14.6 0.1 2.7 2 1 0 2 2 2 1 HEAT repeats ParcG PF10274.4 ETO27813.1 - 0.00043 20.2 0.1 0.00092 19.1 0.0 1.5 1 0 0 1 1 1 1 Parkin co-regulated protein HEAT PF02985.17 ETO27813.1 - 0.0017 18.2 0.0 0.19 11.9 0.0 3.0 2 0 0 2 2 2 1 HEAT repeat UME PF08064.8 ETO27813.1 - 0.022 14.7 0.1 0.09 12.7 0.1 2.1 1 0 0 1 1 1 0 UME (NUC010) domain HEAT_EZ PF13513.1 ETO27813.1 - 0.035 14.6 0.6 14 6.2 0.0 3.8 3 1 1 4 4 4 0 HEAT-like repeat Tim54 PF11711.3 ETO27814.1 - 0.57 8.7 7.0 0.23 9.9 0.2 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Med3 PF11593.3 ETO27814.1 - 0.57 9.3 33.5 0.14 11.3 9.5 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Dicty_REP PF05086.7 ETO27814.1 - 0.66 7.6 15.7 0.17 9.6 7.3 1.9 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Med15 PF09606.5 ETO27814.1 - 1.7 6.7 25.6 0.028 12.6 13.0 1.5 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 ETO27814.1 - 2.9 7.7 19.2 2.4 7.9 6.5 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TPR_12 PF13424.1 ETO27815.1 - 2.6e-50 168.2 11.0 2.2e-20 72.3 0.5 3.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO27815.1 - 9.4e-27 91.4 22.0 3.3e-08 32.8 0.3 5.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO27815.1 - 1e-26 90.5 6.2 0.00041 19.9 0.0 5.2 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETO27815.1 - 1.9e-25 87.9 0.0 2.3e-05 24.1 0.0 4.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO27815.1 - 3.9e-24 84.0 14.3 7e-13 48.0 1.4 2.9 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 ETO27815.1 - 2.2e-23 80.2 16.2 4.3e-06 26.2 0.1 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO27815.1 - 8.3e-16 56.5 21.0 0.00043 19.8 0.8 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO27815.1 - 3.3e-12 45.4 3.3 0.042 13.1 0.1 4.7 5 0 0 5 5 5 3 SHNi-TPR MIT PF04212.13 ETO27815.1 - 8.1e-10 38.4 10.5 0.00052 19.8 0.1 4.1 3 1 1 4 4 4 3 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 ETO27815.1 - 6.8e-09 35.6 1.4 3.1 8.4 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO27815.1 - 1.6e-08 34.0 9.9 0.006 16.6 0.9 4.8 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO27815.1 - 8.7e-06 25.9 0.0 11 6.9 0.0 4.4 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETO27815.1 - 2e-05 25.1 1.0 0.058 14.0 0.0 2.8 1 1 2 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO27815.1 - 0.00025 21.1 9.8 0.17 12.0 1.0 3.4 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF2225 PF09986.4 ETO27815.1 - 0.0079 15.6 7.6 5.6 6.3 5.3 2.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) DUF627 PF04781.7 ETO27815.1 - 0.022 14.3 4.9 8.6 6.0 0.0 4.0 2 2 3 5 5 5 0 Protein of unknown function (DUF627) Sel1 PF08238.7 ETO27815.1 - 0.08 13.6 5.4 27 5.5 0.2 4.2 4 0 0 4 4 4 0 Sel1 repeat TPR_3 PF07720.7 ETO27815.1 - 0.27 11.0 9.5 4.7 7.1 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Ubiq-assoc PF09145.5 ETO27815.1 - 1 9.2 5.8 62 3.5 0.1 3.7 3 1 0 3 3 3 0 Ubiquitin-associated Fis1_TPR_C PF14853.1 ETO27815.1 - 4.8 7.1 7.4 57 3.7 0.1 4.0 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Neur PF00064.13 ETO27816.1 - 0.021 12.9 2.5 0.023 12.7 1.7 1.0 1 0 0 1 1 1 0 Neuraminidase DUF2982 PF11201.3 ETO27817.1 - 0.0064 15.8 0.1 2.6 7.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2982) Kelch_6 PF13964.1 ETO27818.1 - 8.2e-06 25.7 3.4 0.033 14.3 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO27818.1 - 1.6e-05 24.3 13.0 0.015 14.7 0.0 4.5 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 ETO27818.1 - 6.5e-05 22.9 0.2 0.0053 16.8 0.0 3.8 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO27818.1 - 0.00014 21.5 5.5 0.0086 15.8 0.1 3.7 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO27818.1 - 0.0027 17.3 4.2 7.2 6.5 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO27818.1 - 0.87 9.6 3.8 6.9 6.7 0.0 3.5 4 0 0 4 4 4 0 Kelch motif DUF2418 PF10332.4 ETO27819.1 - 2.9 8.2 6.6 30 4.9 4.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2418) TPR_11 PF13414.1 ETO27820.1 - 5.2e-09 35.6 5.0 3.4e-07 29.8 0.5 3.0 3 0 0 3 3 3 2 TPR repeat TPR_16 PF13432.1 ETO27820.1 - 1.2e-06 29.0 1.0 0.048 14.3 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO27820.1 - 1.5e-05 24.3 0.0 4.5e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO27820.1 - 7e-05 22.7 2.2 0.37 11.1 0.1 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO27820.1 - 0.00017 21.2 0.1 0.00097 18.8 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO27820.1 - 0.00046 20.4 1.7 0.007 16.6 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO27820.1 - 0.00048 20.5 0.1 0.37 11.5 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Cupin_8 PF13621.1 ETO27820.1 - 0.0021 17.6 0.3 0.0052 16.3 0.1 1.7 2 0 0 2 2 2 1 Cupin-like domain TPR_8 PF13181.1 ETO27820.1 - 0.079 12.7 1.8 0.23 11.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat C2 PF00168.25 ETO27821.1 - 1.4e-08 34.4 4.6 3e-07 30.2 3.2 2.2 1 1 0 1 1 1 1 C2 domain HlyU PF10115.4 ETO27821.1 - 0.0013 18.4 0.3 0.0035 17.1 0.2 1.7 1 0 0 1 1 1 1 Transcriptional activator HlyU Adenylate_cycl PF01295.13 ETO27821.1 - 0.1 10.8 9.2 0.11 10.7 5.9 1.3 1 1 0 1 1 1 0 Adenylate cyclase, class-I TTL PF03133.10 ETO27822.1 - 2.8e-20 72.4 0.7 2.8e-20 72.4 0.5 1.8 3 0 0 3 3 3 1 Tubulin-tyrosine ligase family DUF4350 PF14258.1 ETO27824.1 - 0.058 13.6 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) Ribonucleas_3_3 PF14622.1 ETO27824.1 - 0.079 12.9 1.6 1.9 8.4 0.2 2.9 2 1 1 3 3 3 0 Ribonuclease-III-like DUF3008 PF11450.3 ETO27825.1 - 0.019 15.0 0.5 0.034 14.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknwon function (DUF3008) Phage_GPA PF05840.8 ETO27825.1 - 0.037 12.7 2.5 0.04 12.6 1.7 1.2 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) DUF3974 PF13120.1 ETO27825.1 - 0.19 11.5 1.6 0.26 11.1 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) SBDS_C PF09377.5 ETO27825.1 - 0.2 11.3 5.4 0.29 10.8 0.7 2.0 1 1 1 2 2 2 0 SBDS protein C-terminal domain DUF4522 PF15022.1 ETO27825.1 - 0.35 10.5 5.6 0.85 9.3 3.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4522) Methyltransf_16 PF10294.4 ETO27825.1 - 0.41 10.0 3.6 4 6.8 0.0 2.0 1 1 1 2 2 2 0 Putative methyltransferase Glucan_synthase PF02364.10 ETO27826.1 - 0.019 12.8 0.9 0.023 12.5 0.6 1.0 1 0 0 1 1 1 0 1,3-beta-glucan synthase component DUF3430 PF11912.3 ETO27826.1 - 0.05 13.4 3.1 0.054 13.3 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3430) Mdv1 PF11542.3 ETO27826.1 - 1.3 9.0 4.1 0.8 9.6 0.3 2.5 2 1 0 2 2 2 0 Mitochondrial division protein 1 zf-CCCH PF00642.19 ETO27827.1 - 8.9e-09 34.8 19.2 2.6e-07 30.1 3.8 3.0 2 1 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 ETO27827.1 - 0.021 14.8 11.5 0.11 12.5 2.8 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Na_trans_assoc PF06512.8 ETO27828.1 - 0.0007 19.6 4.5 0.0007 19.6 3.1 2.2 2 0 0 2 2 2 1 Sodium ion transport-associated zf-DHHC PF01529.15 ETO27828.1 - 0.031 13.6 0.0 0.031 13.6 0.0 2.3 1 1 1 2 2 1 0 DHHC palmitoyltransferase Ctr PF04145.10 ETO27828.1 - 0.07 13.1 3.2 2.9 7.9 0.2 2.4 2 0 0 2 2 2 0 Ctr copper transporter family XAP5 PF04921.9 ETO27828.1 - 0.17 11.4 19.9 0.14 11.6 3.9 2.2 2 0 0 2 2 2 0 XAP5, circadian clock regulator DUF2052 PF09747.4 ETO27828.1 - 0.19 11.6 24.2 0.042 13.7 10.3 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Tim54 PF11711.3 ETO27828.1 - 0.29 9.6 15.4 0.068 11.7 1.4 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 FGF-BP1 PF06473.7 ETO27828.1 - 0.37 10.3 19.6 1.3 8.5 2.4 2.4 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) DUF3340 PF11818.3 ETO27828.1 - 0.43 10.5 22.8 0.077 12.9 7.8 2.2 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) LMBR1 PF04791.11 ETO27828.1 - 0.88 8.0 6.5 0.29 9.6 0.1 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein DUF4045 PF13254.1 ETO27828.1 - 1.3 8.1 15.6 0.2 10.8 2.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) DUF4557 PF15101.1 ETO27828.1 - 1.5 8.6 16.6 0.12 12.1 4.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Dynamin_N PF00350.18 ETO27828.1 - 1.8 8.3 11.3 3.7 7.3 1.0 2.2 2 0 0 2 2 2 0 Dynamin family SR-25 PF10500.4 ETO27828.1 - 1.9 7.9 32.4 0.064 12.7 9.3 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RP-C_C PF11800.3 ETO27828.1 - 1.9 8.1 16.8 2.2 7.9 3.5 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region MMR1 PF08505.5 ETO27828.1 - 2.1 8.3 22.3 1.5 8.8 5.5 2.2 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Gti1_Pac2 PF09729.4 ETO27828.1 - 3.7 7.3 17.3 1.2 8.9 1.9 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family Tau95 PF09734.4 ETO27828.1 - 4.9 6.3 11.2 7.9 5.7 7.8 1.3 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit DUF2201_N PF13203.1 ETO27828.1 - 6.5 5.8 12.4 4.4 6.3 3.4 2.3 2 0 0 2 2 2 0 Putative metallopeptidase domain Band_3_cyto PF07565.8 ETO27828.1 - 7.1 6.0 13.3 1.5 8.2 2.6 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Afi1 PF07792.7 ETO27828.1 - 9.6 6.2 19.6 3.2 7.7 4.5 2.4 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Peptidase_C58 PF03543.9 ETO27828.1 - 9.7 5.6 16.1 1.3 8.4 6.6 2.1 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen PARG_cat PF05028.9 ETO27829.1 - 7.2e-65 219.4 0.7 1.4e-49 169.1 0.3 2.1 2 0 0 2 2 2 2 Poly (ADP-ribose) glycohydrolase (PARG) DUF2919 PF11143.3 ETO27830.1 - 0.022 14.6 0.4 0.058 13.2 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2919) ETRAMP PF09716.5 ETO27830.1 - 3 7.8 7.5 3.1 7.8 3.5 2.2 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DEAD PF00270.24 ETO27831.1 - 4.8e-17 61.9 0.1 6.2e-17 61.6 0.1 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 ETO27831.1 - 0.0017 18.2 0.1 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PSP1 PF04468.7 ETO27832.1 - 0.054 13.4 0.2 0.054 13.4 0.2 1.9 2 1 0 2 2 2 0 PSP1 C-terminal conserved region DUF3440 PF11922.3 ETO27832.1 - 0.06 12.8 3.2 0.28 10.7 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3440) BSP_II PF05432.6 ETO27832.1 - 0.089 12.0 5.1 0.11 11.7 3.5 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) FAM176 PF14851.1 ETO27832.1 - 0.24 11.0 5.3 0.058 13.0 1.0 1.8 2 0 0 2 2 2 0 FAM176 family Adeno_terminal PF02459.10 ETO27832.1 - 0.8 7.7 7.8 0.048 11.8 1.7 1.5 2 0 0 2 2 2 0 Adenoviral DNA terminal protein GOLD_2 PF13897.1 ETO27832.1 - 0.95 9.6 3.4 0.71 10.0 0.8 1.8 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking TMEM51 PF15345.1 ETO27834.1 - 0.00092 18.9 1.6 0.0011 18.6 1.1 1.1 1 0 0 1 1 1 1 Transmembrane protein 51 Neur_chan_memb PF02932.11 ETO27834.1 - 0.0062 16.4 0.6 0.0083 16.0 0.4 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF3068 PF11271.3 ETO27834.1 - 0.02 13.9 0.1 0.022 13.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3068) RCR PF12273.3 ETO27834.1 - 0.069 13.7 0.3 0.13 12.8 0.2 1.5 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red CcmD PF04995.9 ETO27834.1 - 0.11 12.3 0.7 0.22 11.2 0.5 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Cellulose_synt PF03552.9 ETO27834.1 - 0.32 9.2 2.0 0.41 8.8 1.4 1.1 1 0 0 1 1 1 0 Cellulose synthase Dicty_REP PF05086.7 ETO27834.1 - 0.77 7.4 10.6 0.86 7.2 7.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 ETO27834.1 - 1.7 8.3 5.7 2.7 7.7 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Trypan_PARP PF05887.6 ETO27834.1 - 6.6 6.5 8.0 9.1 6.0 5.5 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FYRC PF05965.9 ETO27835.1 - 2.6e-21 75.2 0.0 5.5e-21 74.1 0.0 1.5 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.9 ETO27835.1 - 1.3e-13 50.1 0.0 2.2e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 F/Y-rich N-terminus Spc7 PF08317.6 ETO27836.1 - 3.1e-05 22.8 13.5 5.9e-05 21.8 9.4 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF3584 PF12128.3 ETO27836.1 - 0.00014 19.4 12.7 0.0002 18.8 8.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Mod_r PF07200.8 ETO27836.1 - 0.0037 17.2 5.6 0.0037 17.2 3.9 2.5 1 1 1 2 2 2 1 Modifier of rudimentary (Mod(r)) protein Shisa PF13908.1 ETO27836.1 - 0.0039 17.4 5.1 0.0039 17.4 3.5 2.1 2 1 0 2 2 2 1 Wnt and FGF inhibitory regulator DUF2959 PF11172.3 ETO27836.1 - 0.0063 16.3 4.5 0.011 15.5 3.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2959) DUF1664 PF07889.7 ETO27836.1 - 0.018 14.8 10.7 0.14 11.9 3.6 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Mucin PF01456.12 ETO27836.1 - 0.021 14.6 24.1 0.063 13.0 10.9 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein Orbi_VP5 PF00901.12 ETO27836.1 - 0.023 12.9 10.6 0.032 12.4 7.4 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 UPF0184 PF03670.8 ETO27836.1 - 0.086 13.0 5.2 0.9 9.7 0.6 2.5 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0184) Vps51 PF08700.6 ETO27836.1 - 0.3 10.9 8.4 4.4 7.2 0.2 3.1 2 1 0 2 2 2 0 Vps51/Vps67 DUF948 PF06103.6 ETO27836.1 - 0.3 10.9 8.2 12 5.8 3.2 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Serine_rich PF08824.5 ETO27836.1 - 4 7.1 12.0 0.98 9.1 1.6 2.3 1 1 1 2 2 2 0 Serine rich protein interaction domain DUF2664 PF10867.3 ETO27836.1 - 4.9 7.8 11.4 11 6.7 0.8 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF2664) FliJ PF02050.11 ETO27836.1 - 7.3 6.6 15.7 8.4 6.4 3.5 2.4 1 1 1 2 2 2 0 Flagellar FliJ protein SlyX PF04102.7 ETO27836.1 - 9.2 6.7 12.7 36 4.8 2.5 3.4 2 1 1 3 3 3 0 SlyX RRM_6 PF14259.1 ETO27837.1 - 0.0038 17.1 0.1 0.015 15.2 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO27837.1 - 0.0055 16.3 0.0 0.014 14.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nitrophorin PF02087.10 ETO27837.1 - 0.024 14.4 0.9 0.041 13.6 0.4 1.5 1 1 0 1 1 1 0 Nitrophorin UBA_4 PF14555.1 ETO27838.1 - 3.2e-12 45.7 0.8 9.9e-12 44.1 0.4 2.0 2 0 0 2 2 2 1 UBA-like domain UBX PF00789.15 ETO27838.1 - 1.6e-08 34.4 0.1 3.3e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 UBX domain Vfa1 PF08432.5 ETO27838.1 - 0.85 9.6 12.7 1.3 8.9 8.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 BTV_NS2 PF04514.7 ETO27838.1 - 1.9 7.2 12.9 3 6.6 9.0 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CDC45 PF02724.9 ETO27838.1 - 2.7 5.9 14.1 3.9 5.4 9.8 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 ETO27838.1 - 4.2 6.6 15.0 6.7 6.0 10.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Vma12 PF11712.3 ETO27838.1 - 6.3 6.4 5.8 16 5.1 4.0 1.7 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase MatE PF01554.13 ETO27839.1 - 0.0048 16.5 0.2 0.0065 16.0 0.2 1.3 1 0 0 1 1 1 1 MatE MatE PF01554.13 ETO27840.1 - 6.5e-31 107.1 8.8 6.5e-31 107.1 6.1 2.0 2 0 0 2 2 2 1 MatE DUF2518 PF10726.4 ETO27840.1 - 0.024 14.2 1.0 0.095 12.2 0.7 2.0 1 0 0 1 1 1 0 Protein of function (DUF2518) NESP55 PF06390.7 ETO27840.1 - 0.053 12.9 1.6 0.076 12.3 1.1 1.1 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Prothymosin PF03247.9 ETO27841.1 - 0.027 14.6 13.7 0.048 13.8 9.5 1.5 1 0 0 1 1 1 0 Prothymosin/parathymosin family DUF4551 PF15087.1 ETO27841.1 - 6.9 4.8 7.7 8.1 4.6 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Pkinase PF00069.20 ETO27843.1 - 0.01 15.0 0.0 0.023 13.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain DUF3439 PF11921.3 ETO27843.1 - 0.93 9.2 24.2 3.8 7.2 7.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Kelch_1 PF01344.20 ETO27844.1 - 7.6e-05 22.1 1.3 0.31 10.6 0.0 3.9 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 ETO27844.1 - 0.00049 20.1 1.8 5.4 7.3 0.0 4.3 5 0 0 5 5 5 3 Kelch motif WD40 PF00400.27 ETO27845.1 - 3.9e-57 188.2 16.5 9.1e-12 44.3 0.1 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO27845.1 - 4e-12 46.2 0.4 0.0053 16.4 0.0 3.5 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO27845.1 - 1.6e-10 39.7 6.9 0.014 13.5 0.1 4.8 1 1 4 5 5 5 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO27845.1 - 5.4e-07 29.3 0.1 1.5e-05 24.5 0.1 2.5 1 1 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO27845.1 - 7e-07 27.8 1.5 0.01 14.1 0.0 3.0 1 1 2 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO27845.1 - 9.3e-05 21.3 5.2 0.15 10.7 0.2 3.8 1 1 2 4 4 4 2 Nup133 N terminal like DPPIV_N PF00930.16 ETO27845.1 - 0.0025 16.4 0.4 0.46 9.0 0.0 3.3 1 1 3 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF1797 PF08796.5 ETO27845.1 - 0.011 15.5 0.0 3.7 7.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1797) DUF1513 PF07433.6 ETO27845.1 - 0.017 14.0 0.1 3.2 6.5 0.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1513) PD40 PF07676.7 ETO27845.1 - 0.019 14.6 7.5 12 5.6 0.1 4.7 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 ETO27845.1 - 0.024 13.7 0.8 4.4 6.3 0.0 3.5 1 1 3 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 ETO27845.1 - 0.096 12.0 10.6 13 5.1 0.0 5.4 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature PQQ_3 PF13570.1 ETO27845.1 - 0.12 12.6 0.2 11 6.4 0.0 3.1 3 0 0 3 3 3 0 PQQ-like domain APP_Cu_bd PF12924.2 ETO27846.1 - 0.12 12.9 0.5 0.23 11.9 0.4 1.5 1 0 0 1 1 1 0 Copper-binding of amyloid precursor, CuBD DUF3112 PF11309.3 ETO27846.1 - 0.92 9.2 7.7 5.3 6.8 5.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) ATP-synt_8 PF00895.15 ETO27846.1 - 7.4 6.8 10.0 0.47 10.7 0.4 3.0 2 1 1 3 3 3 0 ATP synthase protein 8 FYVE PF01363.16 ETO27847.1 - 9e-13 47.9 2.6 1.7e-12 47.0 1.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 ETO27847.1 - 0.02 14.7 7.6 0.02 14.7 5.3 2.0 2 1 0 2 2 2 0 FYVE-type zinc finger Arrestin_C PF02752.17 ETO27847.1 - 0.13 12.3 3.7 0.25 11.4 2.6 1.6 1 1 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain BTV_NS2 PF04514.7 ETO27847.1 - 1.1 8.0 9.6 1.3 7.8 6.7 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Nop14 PF04147.7 ETO27847.1 - 1.4 6.7 14.5 1.7 6.5 10.0 1.1 1 0 0 1 1 1 0 Nop14-like family Mon1 PF03164.9 ETO27848.1 - 9.1e-51 172.7 11.3 1.5e-49 168.7 7.8 1.9 1 1 0 1 1 1 1 Trafficking protein Mon1 CCER1 PF15482.1 ETO27848.1 - 0.43 10.1 6.9 0.72 9.4 4.8 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 DUF563 PF04577.9 ETO27849.1 - 1.1e-15 58.0 0.4 1.9e-15 57.3 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF3439 PF11921.3 ETO27852.1 - 0.0075 16.0 10.5 0.017 14.8 7.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Fe-ADH PF00465.14 ETO27853.1 - 1.9e-96 322.8 0.0 2.2e-96 322.6 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 ETO27853.1 - 3.4e-15 56.0 0.0 1e-10 41.3 0.0 2.9 2 1 1 3 3 3 2 Iron-containing alcohol dehydrogenase zf-C2H2 PF00096.21 ETO27854.1 - 0.0097 16.2 1.4 0.032 14.5 1.0 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 ETO27854.1 - 0.029 14.2 0.3 0.074 12.9 0.2 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 ETO27854.1 - 0.07 13.4 0.4 0.23 11.8 0.3 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 ETO27854.1 - 0.81 9.8 6.1 0.12 12.5 0.6 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) CMS1 PF14617.1 ETO27855.1 - 5.3e-10 38.7 0.1 5.4e-10 38.7 0.1 1.1 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 ETO27855.1 - 2.4e-05 23.9 0.2 2.7e-05 23.7 0.1 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Biopterin_H PF00351.16 ETO27856.1 - 2e-96 322.6 0.3 7.2e-50 169.6 0.0 2.9 2 1 1 3 3 3 2 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.20 ETO27856.1 - 0.058 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 ACT domain ACT_4 PF13291.1 ETO27856.1 - 0.16 12.3 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 ACT domain Glyco_transf_52 PF07922.6 ETO27856.1 - 0.19 10.7 2.0 0.32 10.0 1.4 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 52 MBT PF02820.13 ETO27857.1 - 0.0014 18.4 0.1 0.0036 17.2 0.0 1.7 1 0 0 1 1 1 1 mbt repeat Tudor-knot PF11717.3 ETO27857.1 - 0.01 15.4 0.3 0.031 13.9 0.2 1.8 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Methyltransf_11 PF08241.7 ETO27858.1 - 1e-20 73.9 0.0 1.9e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO27858.1 - 1.3e-20 73.4 0.1 1.9e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETO27858.1 - 7e-18 64.5 0.1 1.1e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 ETO27858.1 - 1.4e-15 57.5 0.0 2.6e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETO27858.1 - 1e-12 48.0 0.0 1.5e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO27858.1 - 2.8e-12 47.2 0.0 4.8e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETO27858.1 - 4.7e-09 36.3 0.0 8.6e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO27858.1 - 5.5e-09 36.3 0.0 1.1e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETO27858.1 - 2.3e-08 33.6 0.0 3.2e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.15 ETO27858.1 - 0.00097 18.2 0.0 0.0015 17.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase UPF0020 PF01170.13 ETO27858.1 - 0.0043 16.6 0.0 0.0072 15.9 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.12 ETO27858.1 - 0.0084 15.1 0.1 0.015 14.3 0.0 1.6 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.1 ETO27858.1 - 0.012 15.2 0.0 0.016 14.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain GidB PF02527.10 ETO27858.1 - 0.012 14.7 0.1 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G PrmA PF06325.8 ETO27858.1 - 0.014 14.5 0.0 0.026 13.6 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 ETO27858.1 - 0.015 15.3 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.14 ETO27858.1 - 0.016 14.7 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.5 ETO27858.1 - 0.065 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase CCER1 PF15482.1 ETO27859.1 - 3.8 7.1 8.5 6.7 6.2 5.9 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 RSN1_TM PF13967.1 ETO27860.1 - 0.028 13.9 0.1 0.028 13.9 0.1 2.0 2 0 0 2 2 2 0 Late exocytosis, associated with Golgi transport SAM_1 PF00536.25 ETO27862.1 - 2.2e-08 34.1 0.2 5.9e-08 32.7 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO27862.1 - 5.6e-07 29.3 0.0 1.3e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EF-hand_7 PF13499.1 ETO27862.1 - 6.8e-05 22.9 0.6 0.00024 21.1 0.4 2.0 1 0 0 1 1 1 1 EF-hand domain pair DUF4549 PF15082.1 ETO27862.1 - 0.0017 18.0 1.1 0.006 16.2 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4549) EF-hand_8 PF13833.1 ETO27862.1 - 0.0031 17.0 1.7 0.068 12.8 0.8 2.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 ETO27862.1 - 0.0057 15.8 0.4 0.16 11.3 0.1 2.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 ETO27862.1 - 0.031 14.1 0.2 15 5.7 0.0 3.1 2 0 0 2 2 2 0 EF-hand domain Rhodanese PF00581.15 ETO27863.1 - 2.6e-06 27.7 0.0 4.6e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Cation_efflux PF01545.16 ETO27864.1 - 3.2e-40 137.9 6.5 3.9e-40 137.7 4.5 1.1 1 0 0 1 1 1 1 Cation efflux family RabGAP-TBC PF00566.13 ETO27866.1 - 7.2e-49 166.1 6.4 7.2e-49 166.1 4.5 2.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Secretin_N_2 PF07655.8 ETO27866.1 - 0.043 14.2 2.9 0.096 13.0 2.0 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain RICTOR_V PF14668.1 ETO27867.1 - 2.1 8.3 4.5 0.85 9.6 0.3 2.5 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 Methyltransf_12 PF08242.7 ETO27867.1 - 2.5 8.6 12.8 2.9 8.4 0.0 5.2 6 1 0 6 6 6 0 Methyltransferase domain Arm PF00514.18 ETO27867.1 - 4.4 7.2 7.5 20 5.2 0.1 4.8 5 1 0 5 5 5 0 Armadillo/beta-catenin-like repeat PDR_CDR PF06422.7 ETO27868.1 - 0.3 10.7 4.1 11 5.7 0.0 2.5 2 0 0 2 2 2 0 CDR ABC transporter Macoilin PF09726.4 ETO27869.1 - 0.2 9.8 39.8 0.23 9.7 27.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Utp14 PF04615.8 ETO27869.1 - 2.7 6.0 46.3 3.4 5.7 32.1 1.1 1 0 0 1 1 1 0 Utp14 protein KIAA1328 PF15369.1 ETO27869.1 - 4.6 6.9 21.5 6.2 6.5 14.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 PX PF00787.19 ETO27871.1 - 8.2e-15 54.5 1.4 1.5e-14 53.7 1.0 1.5 1 0 0 1 1 1 1 PX domain DUF1409 PF07197.7 ETO27871.1 - 0.12 12.4 0.2 1.8 8.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) SSP160 PF06933.6 ETO27872.1 - 0.91 7.4 10.0 1.4 6.8 6.9 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 ETO27872.1 - 4.6 7.0 12.1 13 5.5 8.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) STAS PF01740.16 ETO27873.1 - 1.3e-17 63.2 0.0 2.3e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 STAS domain Sulfate_transp PF00916.15 ETO27873.1 - 9.7e-06 24.7 0.1 2.4e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_transp PF00916.15 ETO27874.1 - 6.4e-29 100.8 1.6 1e-28 100.1 1.1 1.3 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 ETO27874.1 - 3.4e-21 74.6 1.8 3.4e-21 74.6 1.3 2.1 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif DUF3245 PF11595.3 ETO27875.1 - 0.073 13.3 7.7 0.15 12.2 5.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3245) DUF720 PF05302.6 ETO27875.1 - 0.6 9.8 5.0 1.1 9.0 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF720) CDC45 PF02724.9 ETO27875.1 - 3.8 5.4 11.2 4.5 5.1 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.20 ETO27877.1 - 2.3e-68 230.1 0.0 3.2e-68 229.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO27877.1 - 2.6e-33 115.1 0.0 3.8e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PX PF00787.19 ETO27877.1 - 1.6e-07 31.0 0.0 4.6e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 PX domain Kinase-like PF14531.1 ETO27877.1 - 1.4e-06 27.5 0.0 4.3e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like IBR PF01485.16 ETO27877.1 - 4.2e-05 23.3 1.5 0.00011 22.0 1.0 1.7 1 0 0 1 1 1 1 IBR domain Kdo PF06293.9 ETO27877.1 - 0.026 13.5 0.0 0.062 12.3 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 ETO27877.1 - 0.079 11.7 0.1 0.17 10.6 0.0 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 DUF1515 PF07439.6 ETO27878.1 - 0.017 14.8 0.1 0.042 13.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) SNARE PF05739.14 ETO27878.1 - 0.031 13.9 0.1 0.066 12.9 0.1 1.6 1 0 0 1 1 1 0 SNARE domain Spc42p PF11544.3 ETO27878.1 - 0.046 13.6 0.1 0.046 13.6 0.1 2.2 3 0 0 3 3 3 0 Spindle pole body component Spc42p Baculo_PEP_C PF04513.7 ETO27878.1 - 0.14 11.9 4.6 0.56 10.0 1.7 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CDC45 PF02724.9 ETO27879.1 - 3.2 5.6 9.8 4.1 5.3 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein PA26 PF04636.8 ETO27879.1 - 3.4 6.2 9.1 4.7 5.8 6.3 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) FAM60A PF15396.1 ETO27879.1 - 8.5 6.0 9.4 13 5.4 6.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A F-box-like PF12937.2 ETO27881.1 - 0.0059 16.3 0.1 0.017 14.8 0.1 1.8 1 0 0 1 1 1 1 F-box-like Phage_int_SAM_4 PF13495.1 ETO27881.1 - 0.04 14.2 0.0 0.14 12.5 0.0 2.0 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain PerB PF06590.6 ETO27881.1 - 0.62 10.3 3.9 0.25 11.6 0.3 2.1 2 1 0 2 2 2 0 PerB protein Macoilin PF09726.4 ETO27882.1 - 0.55 8.4 5.6 0.57 8.3 3.9 1.1 1 0 0 1 1 1 0 Transmembrane protein PAC2 PF09754.4 ETO27884.1 - 2e-09 37.6 0.0 2.7e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 PAC2 family DSPc PF00782.15 ETO27884.1 - 0.064 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PAC2 PF09754.4 ETO27885.1 - 3e-05 23.9 0.0 3.5e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 PAC2 family Pkinase PF00069.20 ETO27886.1 - 1.3e-11 44.1 0.0 3.1e-11 42.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Paramyxo_ncap PF00973.14 ETO27886.1 - 0.0015 17.3 0.0 0.0024 16.6 0.0 1.3 1 0 0 1 1 1 1 Paramyxovirus nucleocapsid protein Tyr_Deacylase PF02580.11 ETO27887.1 - 5.6e-21 75.0 0.0 1.3e-09 38.1 0.0 2.7 2 1 0 2 2 2 2 D-Tyr-tRNA(Tyr) deacylase NST1 PF13945.1 ETO27888.1 - 0.74 9.8 9.7 0.85 9.6 6.7 1.0 1 0 0 1 1 1 0 Salt tolerance down-regulator FAM176 PF14851.1 ETO27888.1 - 2.3 7.8 5.3 3 7.5 3.7 1.2 1 0 0 1 1 1 0 FAM176 family Neur_chan_memb PF02932.11 ETO27888.1 - 2.8 7.7 5.1 3.3 7.5 3.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Paramyxo_ncap PF00973.14 ETO27888.1 - 2.8 6.5 7.4 3.4 6.2 5.1 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein NPR3 PF03666.8 ETO27888.1 - 6.3 5.2 10.0 7.1 5.0 7.0 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 UAA PF08449.6 ETO27889.1 - 1.3e-23 83.3 6.6 3.1e-23 82.1 3.6 2.1 2 0 0 2 2 2 1 UAA transporter family EamA PF00892.15 ETO27889.1 - 0.001 19.0 1.0 0.001 19.0 0.7 2.6 2 1 0 2 2 2 1 EamA-like transporter family PEMT PF04191.8 ETO27889.1 - 0.014 15.4 0.2 0.43 10.7 0.0 2.6 2 0 0 2 2 2 0 Phospholipid methyltransferase Vpu PF00558.14 ETO27889.1 - 0.34 10.4 4.3 9.9 5.8 0.0 3.5 4 0 0 4 4 4 0 Vpu protein UAA PF08449.6 ETO27890.1 - 1.5e-20 73.3 14.7 1.6e-19 69.9 10.2 2.0 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 ETO27890.1 - 8e-05 22.3 12.8 0.011 15.3 8.8 2.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.15 ETO27890.1 - 0.012 15.6 6.9 0.012 15.6 4.8 2.6 2 1 1 3 3 3 0 EamA-like transporter family DUF3671 PF12420.3 ETO27890.1 - 1.4 8.9 8.2 0.93 9.5 2.8 2.1 2 0 0 2 2 2 0 Protein of unknown function TPR_12 PF13424.1 ETO27891.1 - 3.8e-107 350.3 28.7 1.5e-20 72.9 0.4 8.5 4 3 3 9 9 9 9 Tetratricopeptide repeat TPR_11 PF13414.1 ETO27891.1 - 4.9e-52 173.4 36.2 1.3e-11 43.9 3.0 8.4 5 2 2 8 8 8 7 TPR repeat TPR_1 PF00515.23 ETO27891.1 - 1.5e-46 154.2 56.7 2.5e-07 30.0 0.1 14.1 14 0 0 14 14 14 9 Tetratricopeptide repeat TPR_2 PF07719.12 ETO27891.1 - 1.3e-44 146.5 39.8 2.2e-07 30.2 0.3 14.2 14 0 0 14 14 14 10 Tetratricopeptide repeat TPR_10 PF13374.1 ETO27891.1 - 2.9e-44 147.7 0.0 8.5e-05 22.3 0.0 13.1 14 0 0 14 14 14 9 Tetratricopeptide repeat TPR_7 PF13176.1 ETO27891.1 - 4.7e-40 132.2 17.2 5.2e-05 22.7 0.1 12.9 13 0 0 13 13 13 8 Tetratricopeptide repeat TPR_8 PF13181.1 ETO27891.1 - 4.4e-31 104.2 63.4 1.1e-06 28.0 1.2 13.8 14 2 0 14 14 14 9 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO27891.1 - 8.5e-18 63.3 5.7 0.0013 17.9 0.0 7.9 9 0 0 9 9 9 5 SHNi-TPR TPR_16 PF13432.1 ETO27891.1 - 1.2e-16 60.8 0.0 0.0033 18.0 0.0 8.4 5 3 5 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 ETO27891.1 - 3.1e-12 45.9 0.0 0.11 13.2 0.0 9.1 9 2 2 11 11 9 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO27891.1 - 4.7e-12 45.1 17.1 0.24 11.7 0.1 10.3 11 1 0 11 11 10 4 Tetratricopeptide repeat TPR_6 PF13174.1 ETO27891.1 - 8.7e-12 44.6 10.9 0.43 11.1 0.0 9.8 11 0 0 11 11 11 3 Tetratricopeptide repeat Apc3 PF12895.2 ETO27891.1 - 8e-07 29.1 23.4 0.00047 20.2 4.4 5.7 2 2 5 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO27891.1 - 8.7e-07 29.1 0.5 1.9 8.8 0.0 6.2 5 1 3 8 8 8 2 Tetratricopeptide repeat TPR_3 PF07720.7 ETO27891.1 - 0.00014 21.5 33.5 0.24 11.2 0.6 8.9 9 0 0 9 9 8 3 Tetratricopeptide repeat Sel1 PF08238.7 ETO27891.1 - 0.00045 20.7 26.8 0.072 13.7 0.1 9.4 11 0 0 11 11 10 1 Sel1 repeat MIT PF04212.13 ETO27891.1 - 0.00054 19.7 32.7 0.012 15.4 0.3 8.9 10 1 1 11 11 11 3 MIT (microtubule interacting and transport) domain RPN7 PF10602.4 ETO27891.1 - 0.0099 15.2 10.1 5.2 6.4 0.1 5.1 3 1 2 5 5 5 2 26S proteasome subunit RPN7 NACHT PF05729.7 ETO27894.1 - 3.1e-18 65.9 0.1 2.6e-17 62.9 0.0 2.6 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 ETO27894.1 - 0.00057 19.9 0.0 0.0013 18.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 ETO27894.1 - 0.001 18.0 0.5 0.0035 16.2 0.1 2.1 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.1 ETO27894.1 - 0.0016 18.5 0.7 0.0047 17.0 0.0 2.2 2 1 0 2 2 1 1 AAA domain DAP3 PF10236.4 ETO27894.1 - 0.0041 16.0 0.0 0.01 14.8 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_18 PF13238.1 ETO27894.1 - 0.0069 16.6 0.0 0.0069 16.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.12 ETO27894.1 - 0.0095 15.7 1.0 0.026 14.3 0.1 2.2 2 1 1 3 3 3 1 Domain of unknown function DUF87 Arch_ATPase PF01637.13 ETO27894.1 - 0.014 15.1 0.0 0.034 13.8 0.0 1.8 1 0 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 ETO27894.1 - 0.017 15.4 0.0 0.096 12.9 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_25 PF13481.1 ETO27894.1 - 0.028 13.8 0.0 0.11 11.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 ETO27894.1 - 0.028 13.8 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Miro PF08477.8 ETO27894.1 - 0.1 13.0 0.1 0.88 10.0 0.0 2.6 2 1 0 2 2 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 ETO27894.1 - 0.15 11.5 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 ETO27894.1 - 0.25 11.5 2.7 0.48 10.6 0.0 3.0 4 0 0 4 4 3 0 RNA helicase DUF4184 PF13803.1 ETO27895.1 - 0.062 12.6 1.0 0.13 11.5 0.4 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4184) DUF3481 PF11980.3 ETO27895.1 - 0.12 12.2 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) UPF0104 PF03706.8 ETO27895.1 - 0.59 9.3 4.0 1.8 7.7 2.7 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0104) WD40 PF00400.27 ETO27896.1 - 8.8e-64 209.2 25.2 1.2e-12 47.1 0.1 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO27896.1 - 5.7e-13 47.8 11.9 0.00014 20.1 0.8 5.2 1 1 4 5 5 5 5 Nucleoporin Nup120/160 DUF851 PF05867.6 ETO27896.1 - 0.011 15.0 0.1 0.19 10.9 0.0 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF851) DUF3601 PF12208.3 ETO27896.1 - 0.037 13.9 0.0 6.1 6.8 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3601) WD40 PF00400.27 ETO27897.1 - 3e-30 102.9 8.2 4.3e-09 35.9 0.3 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat T4SS PF07996.6 ETO27897.1 - 0.092 12.5 0.9 0.14 11.9 0.6 1.3 1 0 0 1 1 1 0 Type IV secretion system proteins DUF2203 PF09969.4 ETO27897.1 - 0.13 12.4 0.9 0.31 11.2 0.6 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Med9 PF07544.8 ETO27897.1 - 0.13 11.9 2.0 0.26 11.0 1.4 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF1498 PF07385.7 ETO27899.1 - 0.04 13.0 0.0 0.062 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1498) Env-gp36 PF09590.5 ETO27899.1 - 0.088 11.0 0.0 0.12 10.5 0.0 1.1 1 0 0 1 1 1 0 Lentivirus surface glycoprotein WD40 PF00400.27 ETO27900.1 - 0.029 14.2 0.6 0.071 13.0 0.4 1.7 1 0 0 1 1 1 0 WD domain, G-beta repeat DUF719 PF05334.8 ETO27902.1 - 0.26 11.3 2.1 0.92 9.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF719) FH2 PF02181.18 ETO27904.1 - 8.5e-45 153.2 8.9 8.5e-45 153.2 6.2 2.6 2 1 1 3 3 3 1 Formin Homology 2 Domain Gly-zipper_OmpA PF13436.1 ETO27905.1 - 0.05 13.2 6.7 0.025 14.2 2.0 2.4 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Myc_N PF01056.13 ETO27905.1 - 0.32 10.1 6.5 0.051 12.7 1.7 1.7 2 0 0 2 2 2 0 Myc amino-terminal region WD40 PF00400.27 ETO27906.1 - 4.6e-83 270.4 27.5 3.6e-12 45.6 0.5 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Peptidase_C14 PF00656.17 ETO27906.1 - 2.9e-10 40.2 0.1 6.3e-10 39.1 0.1 1.5 1 0 0 1 1 1 1 Caspase domain PD40 PF07676.7 ETO27906.1 - 3e-07 29.9 3.4 1.8 8.2 0.0 6.2 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO27906.1 - 1.3e-06 26.8 12.0 0.066 11.3 0.1 6.0 2 1 5 7 7 7 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO27906.1 - 0.00078 17.8 1.4 0.011 13.9 0.1 2.5 2 1 1 3 3 3 1 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO27906.1 - 0.0029 17.0 5.3 1.3 8.4 0.2 3.6 1 1 2 3 3 3 2 PQQ-like domain DUF3601 PF12208.3 ETO27906.1 - 0.028 14.3 0.1 3.6 7.5 0.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3601) DUF3446 PF11928.3 ETO27906.1 - 0.037 14.2 4.7 0.091 12.9 3.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) DNA_pol_viral_N PF00242.12 ETO27906.1 - 0.22 10.5 3.7 0.34 9.8 2.6 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF2762 PF10960.3 ETO27907.1 - 0.006 16.2 3.9 0.014 15.1 2.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2762) Herpes_UL17 PF04559.7 ETO27907.1 - 0.045 12.3 0.0 0.045 12.3 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL17 protein UPF0515 PF15135.1 ETO27907.1 - 0.19 10.7 2.2 0.12 11.3 0.4 1.4 2 0 0 2 2 2 0 Uncharacterised protein UPF0515 Di19_C PF14571.1 ETO27907.1 - 0.35 11.2 3.4 0.24 11.7 0.9 1.7 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal 7TM_GPCR_Srv PF10323.4 ETO27907.1 - 0.62 9.1 4.7 0.27 10.3 0.4 1.9 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv DUF1180 PF06679.7 ETO27907.1 - 1.8 8.4 7.5 1.4 8.7 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) FlaF PF07309.6 ETO27908.1 - 0.13 12.1 0.2 3.2 7.6 0.0 2.1 2 0 0 2 2 2 0 Flagellar protein FlaF DUF3357 PF11837.3 ETO27909.1 - 0.059 13.2 1.5 0.2 11.4 1.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Sporozoite_P67 PF05642.6 ETO27909.1 - 0.39 8.5 9.9 0.72 7.6 6.9 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.9 ETO27909.1 - 5.6 4.8 25.7 0.16 9.9 9.5 2.2 2 0 0 2 2 2 0 CDC45-like protein SID-1_RNA_chan PF13965.1 ETO27909.1 - 5.7 4.9 11.6 0.19 9.8 1.0 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 IncA PF04156.9 ETO27910.1 - 0.0015 18.1 1.2 0.003 17.1 0.8 1.5 1 0 0 1 1 1 1 IncA protein LAGLIDADG_WhiA PF14527.1 ETO27910.1 - 0.049 13.4 0.2 0.18 11.6 0.1 2.0 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain DUF98 PF01947.11 ETO27910.1 - 2 8.1 6.3 1.7 8.3 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF98) V_ATPase_I PF01496.14 ETO27910.1 - 9.3 3.9 15.1 0.73 7.6 2.1 2.7 2 1 1 3 3 3 0 V-type ATPase 116kDa subunit family DSHCT PF08148.7 ETO27911.1 - 9.6e-29 99.8 0.6 9.6e-29 99.8 0.4 2.3 2 1 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 ETO27912.1 - 1.1e-13 51.0 0.0 3e-13 49.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETO27912.1 - 7.1e-07 29.0 0.1 8e-06 25.6 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.1 ETO27912.1 - 4.7e-05 22.6 1.4 9.5e-05 21.6 1.0 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain IstB_IS21 PF01695.12 ETO27912.1 - 0.018 14.4 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ResIII PF04851.10 ETO27912.1 - 0.023 14.5 0.2 0.023 14.5 0.1 2.2 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit PhoH PF02562.11 ETO27912.1 - 0.029 13.6 0.0 0.055 12.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein CHAP PF05257.11 ETO27912.1 - 0.049 13.2 0.4 0.099 12.3 0.2 1.4 1 0 0 1 1 1 0 CHAP domain TPR_11 PF13414.1 ETO27913.1 - 0.0027 17.2 5.1 0.041 13.5 1.4 3.4 4 1 0 4 4 4 1 TPR repeat Fascin PF06268.8 ETO27913.1 - 0.018 15.1 0.0 0.21 11.6 0.0 2.4 2 1 1 3 3 3 0 Fascin domain TPR_7 PF13176.1 ETO27913.1 - 0.051 13.3 0.4 4.3 7.3 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETO27913.1 - 0.07 13.0 9.8 0.35 10.8 2.2 3.5 1 1 1 2 2 2 0 Tetratricopeptide repeat OATP PF03137.15 ETO27913.1 - 0.16 10.0 0.9 0.23 9.4 0.0 1.6 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family TPR_1 PF00515.23 ETO27913.1 - 0.16 11.6 6.6 0.83 9.3 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1510 PF07423.6 ETO27913.1 - 0.23 10.8 17.6 0.84 8.9 5.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) PBP1_TM PF14812.1 ETO27913.1 - 1.4 9.2 19.7 1.3 9.3 7.3 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RIC3 PF15361.1 ETO27913.1 - 2 8.6 9.3 0.56 10.4 1.9 2.6 3 0 0 3 3 3 0 Resistance to inhibitors of cholinesterase homologue 3 AIF_C PF14721.1 ETO27913.1 - 5.5 7.2 7.0 7.3 6.8 0.6 2.5 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term TPR_1 PF00515.23 ETO27914.1 - 0.00034 20.1 1.8 0.12 11.9 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO27914.1 - 0.00051 20.6 0.6 0.076 13.7 0.0 1.7 1 1 1 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO27914.1 - 0.0013 18.8 1.1 0.0022 18.0 0.5 1.7 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 ETO27914.1 - 0.0013 18.5 2.3 0.75 9.7 0.2 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO27914.1 - 0.0028 17.9 0.0 0.0054 17.0 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETO27914.1 - 0.004 17.0 0.2 0.32 10.9 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO27914.1 - 0.033 13.9 1.3 0.28 11.0 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat SSXT PF05030.7 ETO27914.1 - 0.035 13.6 0.4 0.082 12.4 0.3 1.6 1 0 0 1 1 1 0 SSXT protein (N-terminal region) TPR_2 PF07719.12 ETO27914.1 - 0.042 13.7 1.9 0.19 11.7 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.7 ETO27914.1 - 0.055 13.2 4.3 1.2 8.9 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 ETO27914.1 - 0.087 12.4 1.4 0.23 11.1 0.1 2.0 1 1 0 2 2 2 0 TPR repeat Glyco_hydro_92 PF07971.7 ETO27915.1 - 1.8e-37 129.1 1.1 2.1e-37 128.9 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92 PF07971.7 ETO27916.1 - 1.2e-81 274.8 0.7 3.7e-81 273.2 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 92 Med2 PF11214.3 ETO27916.1 - 0.006 16.5 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 Mediator complex subunit 2 DUF866 PF05907.8 ETO27916.1 - 0.078 12.4 0.2 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) SRA1 PF07304.6 ETO27917.1 - 0.0046 16.6 0.0 0.0051 16.5 0.0 1.2 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) DUF2659 PF10858.3 ETO27917.1 - 0.014 14.7 0.6 0.023 14.1 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2659) Sec16_C PF12931.2 ETO27918.1 - 2.1e-05 24.4 0.4 3e-05 23.8 0.3 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 2OG-FeII_Oxy_3 PF13640.1 ETO27919.1 - 1.4e-12 47.9 0.1 2.4e-12 47.2 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.8 ETO27919.1 - 1.4e-07 30.6 0.0 2.9e-07 29.5 0.0 1.4 1 1 0 1 1 1 1 Poxvirus C4/C10 protein 2OG-FeII_Oxy_4 PF13661.1 ETO27919.1 - 2.5e-05 23.8 0.2 0.00011 21.7 0.1 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 ETO27919.1 - 0.023 14.9 0.4 0.052 13.8 0.3 1.7 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily F-box-like PF12937.2 ETO27919.1 - 0.056 13.1 0.4 0.11 12.1 0.3 1.6 1 0 0 1 1 1 0 F-box-like Mem_trans PF03547.13 ETO27920.1 - 0.19 9.9 1.4 0.19 10.0 1.0 1.3 1 0 0 1 1 1 0 Membrane transport protein MIB_HERC2 PF06701.8 ETO27921.1 - 1.4e-27 95.4 26.2 5.5e-19 67.9 2.7 4.9 5 0 0 5 5 5 4 Mib_herc2 Nop14 PF04147.7 ETO27921.1 - 0.0038 15.2 14.1 0.005 14.8 9.8 1.1 1 0 0 1 1 1 1 Nop14-like family UBA PF00627.26 ETO27921.1 - 0.036 13.9 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain PDCD2_C PF04194.8 ETO27921.1 - 0.13 11.8 7.3 0.22 11.1 5.1 1.3 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain CDC45 PF02724.9 ETO27921.1 - 1.3 6.9 15.9 1.9 6.4 11.0 1.1 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.6 ETO27921.1 - 5.8 6.7 12.5 12 5.7 8.7 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal TLP-20 PF06088.6 ETO27921.1 - 7.2 6.2 11.9 3.8 7.1 6.2 2.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Tom37_C PF11801.3 ETO27921.1 - 9.1 6.1 8.1 16 5.3 5.6 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain Mito_carr PF00153.22 ETO27923.1 - 2.7e-06 27.0 0.0 0.014 15.0 0.0 2.3 2 1 0 2 2 2 2 Mitochondrial carrier protein Neur_chan_memb PF02932.11 ETO27924.1 - 1.4 8.7 8.5 2.4 7.9 5.9 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FLO_LFY PF01698.11 ETO27924.1 - 4.8 5.9 20.4 0.089 11.6 6.9 2.0 1 1 1 2 2 2 0 Floricaula / Leafy protein Pescadillo_N PF06732.6 ETO27925.1 - 1.1e-33 116.7 3.1 1.1e-33 116.7 2.1 2.0 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 ETO27925.1 - 1e-08 35.1 0.0 6.1e-07 29.5 0.0 2.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain RGS PF00615.14 ETO27926.1 - 2.9e-13 49.9 4.5 2.9e-13 49.9 3.1 1.6 2 0 0 2 2 2 1 Regulator of G protein signaling domain BSP_II PF05432.6 ETO27926.1 - 0.33 10.1 26.2 1.4 8.1 0.5 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Glypican PF01153.14 ETO27926.1 - 0.58 8.6 4.9 0.9 8.0 3.4 1.3 1 0 0 1 1 1 0 Glypican DUF3824 PF12868.2 ETO27926.1 - 2.6 8.9 10.8 5.2 8.0 1.9 2.5 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) DAP PF15228.1 ETO27926.1 - 2.8 8.7 8.5 9.4 7.0 2.2 2.9 2 0 0 2 2 2 0 Death-associated protein Cwf_Cwc_15 PF04889.7 ETO27926.1 - 9.1 5.9 26.2 1.7 8.2 10.5 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Guanylate_cyc PF00211.15 ETO27927.1 - 0.05 12.9 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain C2 PF00168.25 ETO27930.1 - 3.3e-08 33.2 0.1 6.8e-08 32.2 0.1 1.6 1 0 0 1 1 1 1 C2 domain UCH PF00443.24 ETO27931.1 - 5.4e-39 133.9 0.9 9.2e-39 133.1 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO27931.1 - 1.3e-13 51.1 1.0 1.5e-13 50.8 0.1 1.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Calpain_III PF01067.17 ETO27931.1 - 3.9e-05 23.3 0.1 8.8e-05 22.1 0.0 1.5 2 0 0 2 2 2 1 Calpain large subunit, domain III Peptidase_C98 PF15499.1 ETO27931.1 - 0.25 10.6 3.0 0.4 9.9 1.3 1.9 1 1 1 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF4366 PF14283.1 ETO27932.1 - 1e-05 25.0 7.2 1e-05 25.0 5.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4366) RNA_polI_A34 PF08208.6 ETO27932.1 - 0.00019 21.1 23.1 0.00019 21.1 16.0 2.4 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 DUF2615 PF11027.3 ETO27932.1 - 0.0015 18.4 0.6 0.0015 18.4 0.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2615) DUF2207 PF09972.4 ETO27932.1 - 0.0018 16.9 0.5 0.0025 16.5 0.3 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) TMEM154 PF15102.1 ETO27932.1 - 0.0076 15.9 5.8 0.0076 15.9 4.0 2.3 2 0 0 2 2 2 1 TMEM154 protein family DUF912 PF06024.7 ETO27932.1 - 0.011 15.7 1.4 0.011 15.7 0.9 3.1 3 1 1 4 4 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3357 PF11837.3 ETO27932.1 - 0.016 15.0 0.7 0.034 14.0 0.0 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF3357) 7TM_GPCR_Srx PF10328.4 ETO27932.1 - 0.026 13.6 7.0 0.045 12.8 4.8 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx PBP1_TM PF14812.1 ETO27932.1 - 0.03 14.6 1.4 0.03 14.6 1.0 3.8 3 1 0 3 3 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1676 PF07898.8 ETO27932.1 - 0.068 13.4 0.6 0.068 13.4 0.4 3.3 3 1 0 3 3 2 0 Protein of unknown function (DUF1676) Glt_symporter PF03616.9 ETO27932.1 - 0.077 11.4 3.5 0.14 10.5 2.4 1.5 1 0 0 1 1 1 0 Sodium/glutamate symporter MFS_2 PF13347.1 ETO27932.1 - 0.082 11.2 0.0 0.082 11.2 0.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein Baculo_11_kDa PF06143.6 ETO27932.1 - 0.11 11.8 1.7 0.36 10.2 1.2 1.9 1 0 0 1 1 1 0 Baculovirus 11 kDa family O-ag_pol_Wzy PF14296.1 ETO27932.1 - 0.15 10.6 3.7 0.29 9.6 2.6 1.5 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy 7tm_6 PF02949.15 ETO27932.1 - 0.21 10.4 2.2 0.74 8.6 0.0 2.3 3 0 0 3 3 3 0 7tm Odorant receptor 7TM_GPCR_Srv PF10323.4 ETO27932.1 - 0.22 10.6 3.4 0.37 9.8 2.4 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv T2SF PF00482.18 ETO27932.1 - 0.27 11.1 1.6 0.49 10.2 1.1 1.5 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F CENP-B_dimeris PF09026.5 ETO27932.1 - 0.53 10.5 5.9 0.19 11.9 0.2 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF2899 PF11449.3 ETO27932.1 - 0.62 9.1 3.1 1.3 8.1 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2899) TLC PF03219.9 ETO27932.1 - 2 6.7 8.4 2.9 6.2 5.8 1.1 1 0 0 1 1 1 0 TLC ATP/ADP transporter 7TM_GPCR_Sru PF10322.4 ETO27932.1 - 2.8 6.9 7.5 4.9 6.1 5.2 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru TMEM223 PF14640.1 ETO27932.1 - 3.5 7.5 6.2 0.48 10.3 0.1 2.4 2 1 1 3 3 3 0 Transmembrane protein 223 ATP-synt_8 PF00895.15 ETO27932.1 - 8.3 6.6 10.1 7.2 6.9 5.8 1.8 1 1 0 1 1 1 0 ATP synthase protein 8 DUF1191 PF06697.7 ETO27932.1 - 8.9 5.0 8.5 0.38 9.5 1.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) SID-1_RNA_chan PF13965.1 ETO27932.1 - 9.3 4.2 9.0 0.3 9.2 2.2 1.4 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 zf-HC5HC2H PF13771.1 ETO27933.1 - 1.1e-14 54.3 8.7 1.1e-14 54.3 6.1 2.3 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 ETO27933.1 - 6.1e-11 42.3 10.2 7.7e-11 41.9 5.2 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain Pertus-S4-tox PF09275.5 ETO27933.1 - 0.032 14.3 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 Pertussis toxin S4 subunit AAA PF00004.24 ETO27934.1 - 2.9e-42 143.9 0.0 2.3e-40 137.8 0.0 2.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETO27934.1 - 7.8e-08 32.5 0.2 1e-05 25.6 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 ETO27934.1 - 5.7e-06 26.1 0.0 1.4e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 ETO27934.1 - 6.6e-06 26.1 0.1 3.7e-05 23.7 0.0 2.2 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 ETO27934.1 - 1.4e-05 25.1 2.4 0.0018 18.3 0.0 3.3 3 1 1 4 4 4 1 AAA ATPase domain AAA_11 PF13086.1 ETO27934.1 - 0.00017 21.2 0.0 0.0053 16.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 ETO27934.1 - 0.00019 21.5 0.0 0.00075 19.6 0.0 2.0 1 1 0 1 1 1 1 RNA helicase AAA_33 PF13671.1 ETO27934.1 - 0.00041 20.2 0.0 0.0066 16.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 ETO27934.1 - 0.0012 18.7 0.0 0.0037 17.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 ETO27934.1 - 0.0035 17.0 0.5 0.034 13.7 0.0 2.8 2 1 0 2 2 2 1 NACHT domain DUF2075 PF09848.4 ETO27934.1 - 0.0035 16.3 0.1 0.0097 14.9 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) RuvB_N PF05496.7 ETO27934.1 - 0.0046 16.0 0.0 0.014 14.4 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 ETO27934.1 - 0.0054 16.1 0.2 1.2 8.5 0.0 3.2 2 1 1 3 3 3 1 AAA domain AAA_19 PF13245.1 ETO27934.1 - 0.0068 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 ETO27934.1 - 0.0096 16.7 0.0 0.044 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain Guanylate_kin PF00625.16 ETO27934.1 - 0.022 14.2 0.1 0.28 10.6 0.0 2.5 2 0 0 2 2 2 0 Guanylate kinase AAA_18 PF13238.1 ETO27934.1 - 0.022 15.0 0.0 0.12 12.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 ETO27934.1 - 0.037 13.9 0.0 0.22 11.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.11 ETO27934.1 - 0.039 12.7 0.1 0.11 11.2 0.0 1.7 2 0 0 2 2 2 0 AFG1-like ATPase AAA_3 PF07726.6 ETO27934.1 - 0.04 13.5 0.0 0.39 10.3 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.4 ETO27934.1 - 0.045 12.3 1.3 0.12 11.0 0.0 2.2 2 1 1 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Mg_chelatase PF01078.16 ETO27934.1 - 0.067 12.3 0.1 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 ETO27934.1 - 0.078 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain PIP5K PF01504.13 ETO27935.1 - 9.4e-27 93.7 0.0 1.2e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase SAM_1 PF00536.25 ETO27937.1 - 9.7e-07 28.8 0.8 1.9e-06 27.9 0.1 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO27937.1 - 5.5e-06 26.1 0.1 1.3e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RNA_pol_Rpb1_5 PF04998.12 ETO27940.1 - 1e-83 280.8 0.3 1.7e-83 280.0 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_4 PF05000.12 ETO27940.1 - 3.4e-29 100.7 0.0 1.4e-28 98.7 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_3 PF04983.13 ETO27940.1 - 1.3e-09 37.9 0.0 2.7e-08 33.7 0.0 2.9 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 DDE_Tnp_1 PF01609.16 ETO27940.1 - 0.053 13.0 0.2 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 Transposase DDE domain Nitroreductase PF00881.19 ETO27941.1 - 1e-27 96.9 0.0 5.9e-27 94.5 0.0 2.0 1 1 0 1 1 1 1 Nitroreductase family PMBR PF09373.5 ETO27941.1 - 0.015 15.2 0.1 0.047 13.6 0.0 1.9 2 0 0 2 2 2 0 Pseudomurein-binding repeat WD40 PF00400.27 ETO27942.1 - 3.1e-27 93.4 2.8 8.3e-12 44.5 0.2 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO27942.1 - 0.0037 15.4 0.0 2.3 6.2 0.0 2.7 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO27942.1 - 0.046 12.4 1.4 0.083 11.6 0.7 1.6 1 1 1 2 2 2 0 Nup133 N terminal like GFA PF04828.9 ETO27945.1 - 4.5e-11 42.5 1.5 4.5e-11 42.5 1.1 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_L37e PF01907.14 ETO27945.1 - 0.018 14.8 0.6 0.058 13.2 0.4 1.9 1 0 0 1 1 1 0 Ribosomal protein L37e DUF604 PF04646.7 ETO27945.1 - 0.15 11.2 1.4 0.27 10.4 0.2 1.8 1 1 0 2 2 2 0 Protein of unknown function, DUF604 FliJ PF02050.11 ETO27946.1 - 0.086 12.8 4.5 0.26 11.3 0.5 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein SlyX PF04102.7 ETO27946.1 - 0.096 13.0 3.5 0.29 11.5 0.3 2.4 2 0 0 2 2 2 0 SlyX DUF4446 PF14584.1 ETO27946.1 - 0.16 11.8 4.6 0.096 12.5 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) HSCB_C PF07743.8 ETO27946.1 - 3.1 8.3 7.1 0.64 10.5 0.4 2.3 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain Herpes_UL6 PF01763.11 ETO27947.1 - 0.014 13.5 3.1 0.015 13.5 2.0 1.2 1 1 0 1 1 1 0 Herpesvirus UL6 like Herpes_UL92 PF03048.9 ETO27947.1 - 0.042 13.4 4.4 0.047 13.2 3.1 1.1 1 0 0 1 1 1 0 UL92 family DUF479 PF04336.7 ETO27947.1 - 0.047 13.7 1.7 0.069 13.2 1.2 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF479 HSCB_C PF07743.8 ETO27947.1 - 0.048 14.1 3.6 0.098 13.1 1.7 2.0 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain SVA PF05326.6 ETO27947.1 - 0.066 12.9 4.3 0.069 12.9 3.0 1.0 1 0 0 1 1 1 0 Seminal vesicle autoantigen (SVA) Ferritin-like PF12902.2 ETO27947.1 - 0.09 12.3 2.8 0.11 12.1 2.0 1.1 1 0 0 1 1 1 0 Ferritin-like DUF496 PF04363.7 ETO27947.1 - 0.12 12.2 2.7 0.11 12.3 1.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF496) AF0941-like PF14591.1 ETO27947.1 - 0.14 12.2 4.8 0.065 13.2 1.3 1.7 1 1 1 2 2 2 0 AF0941-like Uds1 PF15456.1 ETO27947.1 - 0.14 12.1 5.4 0.16 11.9 3.7 1.1 1 0 0 1 1 1 0 Up-regulated During Septation Bac_GDH PF05088.7 ETO27947.1 - 0.15 9.3 5.1 0.17 9.2 3.5 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase CorA PF01544.13 ETO27947.1 - 0.16 10.9 3.2 0.18 10.8 2.2 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Cytokin-bind PF09265.5 ETO27947.1 - 0.17 11.0 2.7 0.2 10.7 1.8 1.0 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding DUF4253 PF14062.1 ETO27947.1 - 0.18 11.4 0.9 0.74 9.4 0.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4253) DUF725 PF05267.7 ETO27947.1 - 0.18 11.7 5.3 0.14 12.0 2.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF725) Picorna_P3A PF06363.6 ETO27947.1 - 0.26 11.3 3.4 0.11 12.4 0.7 1.7 2 0 0 2 2 2 0 Picornaviridae P3A protein Spore_III_AB PF09548.5 ETO27947.1 - 0.26 11.0 4.6 0.22 11.2 1.3 1.9 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) RRF PF01765.14 ETO27947.1 - 0.32 10.4 8.0 0.42 10.0 5.5 1.2 1 0 0 1 1 1 0 Ribosome recycling factor DUF4356 PF14266.1 ETO27947.1 - 0.32 9.3 7.9 0.36 9.1 5.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4356) UCR_hinge PF02320.11 ETO27947.1 - 0.55 10.2 4.8 1.3 9.0 3.3 1.6 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein Fib_alpha PF08702.5 ETO27947.1 - 0.7 10.0 10.9 1.2 9.2 7.6 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF573 PF04504.9 ETO27947.1 - 0.8 10.0 8.4 5.6 7.3 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF573 OmpH PF03938.9 ETO27947.1 - 1.2 9.0 13.4 1.5 8.7 9.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Synaptobrevin PF00957.16 ETO27947.1 - 1.3 8.7 7.5 1.4 8.5 1.9 2.6 1 1 1 2 2 2 0 Synaptobrevin PRESAN PF09687.5 ETO27947.1 - 2 8.4 8.1 2.4 8.1 5.6 1.1 1 0 0 1 1 1 0 Plasmodium RESA N-terminal Med11 PF10280.4 ETO27947.1 - 2.5 8.1 8.3 8.1 6.5 5.0 2.0 1 1 1 2 2 2 0 Mediator complex protein Ada3 PF10198.4 ETO27947.1 - 3.3 7.4 11.7 3.7 7.3 3.3 2.1 1 1 1 2 2 2 0 Histone acetyltransferases subunit 3 ADIP PF11559.3 ETO27947.1 - 3.7 7.4 13.5 18 5.1 9.4 1.9 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding JAB PF01398.16 ETO27948.1 - 0.00028 20.5 0.1 0.00058 19.5 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Med9 PF07544.8 ETO27949.1 - 0.037 13.7 0.5 0.037 13.7 0.3 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 PgaD PF13994.1 ETO27949.1 - 0.2 11.1 1.2 0.8 9.1 0.0 2.4 3 0 0 3 3 3 0 PgaD-like protein F-box PF00646.28 ETO27952.1 - 0.0012 18.4 0.0 0.0034 16.9 0.0 1.7 2 0 0 2 2 2 1 F-box domain RST PF12174.3 ETO27952.1 - 0.06 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain COX15-CtaA PF02628.10 ETO27953.1 - 5.1e-46 156.9 0.0 6e-46 156.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein OST3_OST6 PF04756.8 ETO27954.1 - 1e-08 34.9 2.7 2.6e-08 33.5 0.1 2.1 2 0 0 2 2 2 1 OST3 / OST6 family DUF4386 PF14329.1 ETO27954.1 - 0.014 14.8 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) IFNGR1 PF07140.6 ETO27954.1 - 0.08 12.6 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Interferon gamma receptor (IFNGR1) DUF4229 PF14012.1 ETO27954.1 - 0.087 12.7 0.0 0.22 11.4 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4229) 2OG-FeII_Oxy_3 PF13640.1 ETO27956.1 - 0.046 14.2 0.3 0.25 11.8 0.0 2.3 3 0 0 3 3 3 0 2OG-Fe(II) oxygenase superfamily Na_Ca_ex PF01699.19 ETO27957.1 - 5.7e-32 110.2 31.1 2.8e-24 85.3 9.7 2.8 2 1 1 3 3 3 2 Sodium/calcium exchanger protein ArfGap PF01412.13 ETO27958.1 - 0.00022 20.9 0.5 0.00022 20.9 0.3 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf CW_binding_1 PF01473.15 ETO27958.1 - 0.38 10.9 4.0 0.79 9.9 0.5 2.9 2 0 0 2 2 2 0 Putative cell wall binding repeat HEAT PF02985.17 ETO27959.1 - 7.1e-14 50.5 0.5 5.7e-06 25.9 0.0 4.1 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.1 ETO27959.1 - 1.1e-12 48.0 0.0 1.5e-06 28.3 0.0 3.1 2 1 1 3 3 3 2 HEAT repeats Arm PF00514.18 ETO27959.1 - 7.3e-12 44.6 1.0 3.4e-05 23.4 0.0 5.1 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 ETO27959.1 - 7.5e-06 26.2 0.0 0.054 14.0 0.0 3.2 3 0 0 3 3 3 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 ETO27959.1 - 0.019 15.3 3.5 0.023 15.0 0.0 2.8 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region RICTOR_N PF14664.1 ETO27959.1 - 0.027 13.0 0.2 0.27 9.7 0.1 2.2 2 1 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term U-box PF04564.10 ETO27961.1 - 2.6e-10 40.0 0.1 1.2e-09 38.0 0.1 2.2 1 1 0 1 1 1 1 U-box domain DUF4407 PF14362.1 ETO27961.1 - 0.011 14.7 4.8 0.024 13.6 3.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.14 ETO27961.1 - 0.51 8.1 19.7 0.78 7.5 13.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Legionella_OMP PF05150.7 ETO27962.1 - 0.0089 15.1 0.2 0.013 14.6 0.1 1.2 1 0 0 1 1 1 1 Legionella pneumophila major outer membrane protein precursor DUF2205 PF10224.4 ETO27962.1 - 0.046 13.2 0.2 0.066 12.7 0.1 1.5 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) Ubie_methyltran PF01209.13 ETO27962.1 - 0.17 10.9 0.8 0.3 10.1 0.3 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF3128 PF11326.3 ETO27963.1 - 0.11 12.6 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) zf-C4_ClpX PF06689.8 ETO27963.1 - 0.13 11.7 0.2 0.29 10.6 0.1 1.5 1 0 0 1 1 1 0 ClpX C4-type zinc finger Abhydrolase_1 PF00561.15 ETO27964.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold Phasin PF05597.6 ETO27965.1 - 0.011 15.5 2.1 0.012 15.3 1.2 1.3 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF3263 PF11662.3 ETO27965.1 - 0.068 12.6 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3263) adh_short PF00106.20 ETO27966.1 - 1.8e-15 57.2 0.0 2.3e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETO27966.1 - 1.5e-06 27.9 0.0 2.2e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ETO27966.1 - 0.00017 21.6 0.0 0.00022 21.2 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETO27966.1 - 0.019 14.3 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.8 ETO27966.1 - 0.022 14.0 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family AAA PF00004.24 ETO27967.1 - 5.4e-16 59.0 0.4 2.8e-15 56.6 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Selenoprotein_S PF06936.6 ETO27969.1 - 0.41 10.1 2.2 0.48 9.9 1.5 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) Daxx PF03344.10 ETO27969.1 - 0.44 8.9 12.7 0.52 8.7 8.8 1.0 1 0 0 1 1 1 0 Daxx Family PRELI PF04707.9 ETO27970.1 - 1.3e-34 118.9 0.0 1.8e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family RRM_6 PF14259.1 ETO27971.1 - 1.3e-06 28.3 0.1 3.3e-06 26.9 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO27971.1 - 0.00079 19.2 0.0 0.0019 17.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO27971.1 - 0.001 18.6 0.2 0.0037 16.8 0.1 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CHAT PF12770.2 ETO27972.1 - 1.3e-09 37.6 0.0 2.2e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 CHAT domain IlvN PF07991.7 ETO27972.1 - 0.21 10.9 0.0 1.5 8.1 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Neurochondrin PF05536.6 ETO27973.1 - 0.0045 15.3 1.7 0.0069 14.7 1.2 1.2 1 1 0 1 1 1 1 Neurochondrin RICTOR_V PF14668.1 ETO27973.1 - 0.013 15.4 0.5 0.071 13.0 0.0 2.3 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 RRM_1 PF00076.17 ETO27974.1 - 2.3e-13 49.5 1.6 2e-10 40.1 0.1 4.5 4 1 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO27974.1 - 5.9e-12 45.3 0.2 4.8e-08 32.8 0.0 3.6 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO27974.1 - 5e-05 23.0 0.6 0.019 14.8 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.1 ETO27974.1 - 0.0026 17.1 0.0 0.17 11.3 0.0 3.3 2 0 0 2 2 2 1 Sporulation protein family 7 ADIP PF11559.3 ETO27975.1 - 0.0031 17.4 1.8 0.0047 16.8 1.2 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding AAA_13 PF13166.1 ETO27975.1 - 0.0073 14.8 1.0 0.01 14.3 0.1 1.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 ETO27975.1 - 0.0073 16.5 0.3 0.017 15.2 0.2 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DegS PF05384.6 ETO27975.1 - 0.01 15.0 0.8 0.016 14.4 0.6 1.2 1 0 0 1 1 1 0 Sensor protein DegS AAA_19 PF13245.1 ETO27975.1 - 0.027 14.2 0.1 0.056 13.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain ATG16 PF08614.6 ETO27975.1 - 0.031 14.1 1.4 0.043 13.6 1.0 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) HR1 PF02185.11 ETO27975.1 - 0.041 13.6 0.7 0.07 12.8 0.5 1.3 1 0 0 1 1 1 0 Hr1 repeat Tropomyosin_1 PF12718.2 ETO27975.1 - 0.042 13.6 1.4 0.062 13.1 1.0 1.2 1 0 0 1 1 1 0 Tropomyosin like AAA_16 PF13191.1 ETO27975.1 - 0.054 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.1 ETO27975.1 - 0.062 12.8 0.2 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 ETO27975.1 - 0.071 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein WEMBL PF05701.6 ETO27976.1 - 0.00064 18.3 3.2 0.00078 18.0 2.2 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Spc7 PF08317.6 ETO27976.1 - 0.001 17.8 2.5 0.0011 17.6 1.7 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Filament PF00038.16 ETO27976.1 - 0.0042 16.6 4.2 0.0055 16.2 2.9 1.1 1 0 0 1 1 1 1 Intermediate filament protein Spc24 PF08286.6 ETO27976.1 - 0.005 16.5 2.7 0.0066 16.1 1.8 1.2 1 0 0 1 1 1 1 Spc24 subunit of Ndc80 NUC194 PF08163.7 ETO27976.1 - 0.011 14.5 2.4 0.013 14.3 1.7 1.1 1 0 0 1 1 1 0 NUC194 domain Golgin_A5 PF09787.4 ETO27976.1 - 0.015 13.8 5.9 0.018 13.5 3.7 1.3 1 1 0 1 1 1 0 Golgin subfamily A member 5 Cast PF10174.4 ETO27976.1 - 0.017 13.1 7.0 0.017 13.1 4.9 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone IncA PF04156.9 ETO27976.1 - 0.048 13.2 6.3 0.064 12.8 4.4 1.2 1 0 0 1 1 1 0 IncA protein SlyX PF04102.7 ETO27976.1 - 0.35 11.2 5.3 1 9.8 3.6 1.8 1 1 0 1 1 1 0 SlyX Mnd1 PF03962.10 ETO27976.1 - 1.8 8.2 9.0 3 7.4 6.2 1.5 1 1 0 1 1 1 0 Mnd1 family LAMTOR PF15454.1 ETO27976.1 - 1.9 8.8 5.7 0.77 10.0 0.4 2.3 1 1 1 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF948 PF06103.6 ETO27977.1 - 0.07 12.9 0.3 0.07 12.9 0.2 4.5 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.7 ETO27977.1 - 0.21 11.4 23.9 0.16 11.8 3.3 3.6 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.7 ETO27977.1 - 0.44 10.9 43.0 2 8.8 3.7 4.8 3 1 2 5 5 5 0 SlyX Tropomyosin_1 PF12718.2 ETO27977.1 - 1.6 8.5 48.5 1.1 9.0 13.5 3.2 2 1 1 3 3 3 0 Tropomyosin like Ribosomal_S6 PF01250.12 ETO27978.1 - 9.2e-07 28.6 0.0 5.3e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S6 DUF179 PF02622.10 ETO27981.1 - 2.4e-05 23.9 0.1 0.00018 21.1 0.1 2.1 1 1 0 1 1 1 1 Uncharacterized ACR, COG1678 Nop14 PF04147.7 ETO27981.1 - 0.0026 15.7 12.9 0.0036 15.3 9.0 1.1 1 0 0 1 1 1 1 Nop14-like family Myc_N PF01056.13 ETO27981.1 - 0.0057 15.8 9.5 0.0057 15.8 6.6 1.6 1 1 1 2 2 2 1 Myc amino-terminal region Dsh_C PF12316.3 ETO27981.1 - 0.013 15.6 4.4 0.021 14.9 3.1 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal CDC45 PF02724.9 ETO27981.1 - 0.061 11.3 14.2 0.088 10.8 9.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 ETO27981.1 - 0.13 10.7 15.2 0.18 10.2 10.6 1.1 1 0 0 1 1 1 0 Daxx Family Pox_RNA_Pol_19 PF05320.7 ETO27981.1 - 0.15 11.8 11.1 0.27 10.9 7.7 1.4 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Sigma70_ner PF04546.8 ETO27981.1 - 0.19 11.3 10.5 0.32 10.5 7.3 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 ETO27981.1 - 0.59 9.6 9.3 1.1 8.7 6.5 1.4 1 0 0 1 1 1 0 Nucleoplasmin DUF1510 PF07423.6 ETO27981.1 - 7.2 5.9 18.6 13 5.0 12.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ribosomal_L22 PF00237.14 ETO27982.1 - 2.3e-21 75.6 0.1 3.4e-21 75.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ist1 PF03398.9 ETO27983.1 - 3.1e-29 101.5 7.8 8.3e-19 67.5 2.7 3.1 2 1 0 2 2 2 2 Regulator of Vps4 activity in the MVB pathway PDZ_2 PF13180.1 ETO27984.1 - 0.037 13.9 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 PDZ domain ABC1 PF03109.11 ETO27985.1 - 1.2e-19 70.4 0.0 2.3e-08 34.0 0.0 2.5 2 0 0 2 2 2 2 ABC1 family PBP1_TM PF14812.1 ETO27985.1 - 0.0069 16.6 1.0 0.0069 16.6 0.7 2.3 3 0 0 3 3 3 1 Transmembrane domain of transglycosylase PBP1 at N-terminal APH PF01636.18 ETO27985.1 - 0.011 15.5 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family alpha-hel2 PF14456.1 ETO27985.1 - 4.3 6.0 7.2 2.5 6.7 0.1 2.1 2 0 0 2 2 2 0 Alpha-helical domain 2 WD40 PF00400.27 ETO27986.1 - 7.2e-70 228.5 15.0 2.5e-14 52.5 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO27986.1 - 6.6e-12 45.5 0.0 0.00027 20.6 0.0 3.7 1 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO27986.1 - 9.5e-09 33.9 1.5 0.026 12.6 0.0 4.1 1 1 3 5 5 5 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO27986.1 - 1.2e-05 23.7 1.3 0.041 12.1 0.0 3.6 2 1 2 4 4 4 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO27986.1 - 0.00012 21.6 0.2 0.0022 17.5 0.2 2.8 1 1 0 1 1 1 1 PQQ-like domain Utp8 PF10395.4 ETO27986.1 - 0.0025 16.2 3.1 0.65 8.2 0.0 3.4 3 1 1 4 4 4 2 Utp8 family PD40 PF07676.7 ETO27986.1 - 0.003 17.1 2.9 21 4.8 0.0 5.0 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat B_lectin PF01453.19 ETO27986.1 - 0.0051 16.6 1.3 0.11 12.3 0.1 3.4 3 1 2 5 5 5 2 D-mannose binding lectin Nucleoporin_N PF08801.6 ETO27986.1 - 0.01 14.5 5.6 0.054 12.2 1.1 3.4 1 1 2 3 3 3 0 Nup133 N terminal like Hira PF07569.6 ETO27986.1 - 0.05 12.8 0.0 15 4.7 0.0 3.3 2 2 1 3 3 3 0 TUP1-like enhancer of split Proteasome_A_N PF10584.4 ETO27986.1 - 0.6 9.4 10.4 34 3.8 0.0 5.1 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature RRM_1 PF00076.17 ETO27989.1 - 2.9e-44 148.5 0.1 6.8e-20 70.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO27989.1 - 7.3e-35 118.7 0.0 3.7e-14 52.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 ETO27989.1 - 1.6e-28 98.1 1.2 4.7e-28 96.6 0.8 1.8 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.1 ETO27989.1 - 2.6e-15 56.0 0.1 2e-07 30.7 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETO27989.1 - 0.018 14.7 0.0 5.8 6.7 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Sporozoite_P67 PF05642.6 ETO27989.1 - 9.7 3.9 12.4 16 3.1 8.6 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.7 ETO27990.1 - 0.011 13.7 15.2 0.015 13.2 10.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 ETO27990.1 - 0.011 15.0 9.9 0.65 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) BUD22 PF09073.5 ETO27990.1 - 0.069 12.2 12.8 0.099 11.6 8.9 1.2 1 0 0 1 1 1 0 BUD22 SMN PF06003.7 ETO27990.1 - 0.072 12.1 11.6 0.23 10.5 8.0 1.7 1 1 0 1 1 1 0 Survival motor neuron protein (SMN) CENP-T PF15511.1 ETO27990.1 - 0.1 11.8 9.9 0.14 11.4 6.9 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Gemini_mov PF01708.11 ETO27990.1 - 0.13 11.8 0.0 0.29 10.6 0.0 1.6 1 1 0 1 1 1 0 Geminivirus putative movement protein Vfa1 PF08432.5 ETO27990.1 - 0.19 11.7 10.5 0.18 11.8 0.9 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 ETO27990.1 - 0.7 7.8 12.5 0.1 10.6 3.4 2.0 2 0 0 2 2 2 0 CDC45-like protein TFIIA PF03153.8 ETO27990.1 - 1.3 8.8 16.0 1.9 8.2 11.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit YL1 PF05764.8 ETO27990.1 - 5.4 6.5 14.9 3.9 7.0 4.7 2.1 2 0 0 2 2 2 0 YL1 nuclear protein Imm22 PF15592.1 ETO27992.1 - 0.061 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 22 Mu-like_Pro PF10123.4 ETO27993.1 - 0.17 11.3 3.4 0.17 11.3 2.4 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein ABC_membrane_2 PF06472.10 ETO27994.1 - 1.2e-09 37.6 5.8 1.7e-09 37.2 4.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 FAM176 PF14851.1 ETO27995.1 - 0.018 14.7 0.1 1.3 8.6 0.1 2.5 2 0 0 2 2 2 0 FAM176 family DUF4515 PF14988.1 ETO27997.1 - 0.0081 15.8 3.8 0.011 15.3 2.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4515) Peptidase_M3 PF01432.15 ETO27998.1 - 1.2e-120 403.6 2.3 2.2e-104 350.0 0.1 2.4 2 0 0 2 2 2 2 Peptidase family M3 ATP-synt_8 PF00895.15 ETO27999.1 - 1.6 8.9 0.0 1.6 8.9 0.0 3.7 3 0 0 3 3 3 0 ATP synthase protein 8 Zip PF02535.17 ETO27999.1 - 5.7 5.8 7.2 19 4.1 5.0 2.0 1 1 0 1 1 1 0 ZIP Zinc transporter IpaD PF06511.6 ETO28000.1 - 0.14 11.1 1.6 0.23 10.4 1.1 1.3 1 0 0 1 1 1 0 Invasion plasmid antigen IpaD Pkinase PF00069.20 ETO28001.1 - 4e-70 235.9 0.5 1.1e-69 234.4 0.4 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO28001.1 - 8.3e-44 149.5 0.2 7.2e-43 146.5 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO28001.1 - 1.2e-06 27.7 0.1 0.051 12.5 0.0 3.3 3 1 1 4 4 4 2 Kinase-like YrbL-PhoP_reg PF10707.4 ETO28001.1 - 0.00081 18.7 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 ETO28001.1 - 0.0079 15.5 0.4 0.02 14.2 0.1 1.8 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 ETO28001.1 - 0.02 13.9 0.5 0.034 13.2 0.4 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 ETO28001.1 - 0.039 12.7 0.0 0.063 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 ETO28001.1 - 0.07 12.8 3.3 0.25 11.0 0.4 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family DEAD PF00270.24 ETO28004.1 - 1.2e-24 86.6 2.4 2.6e-22 79.1 0.5 3.0 2 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 ETO28004.1 - 9.6e-19 67.0 0.4 4.9e-18 64.7 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETO28004.1 - 2.8e-09 37.0 0.4 1.2e-08 34.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 ETO28004.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain GPCR_chapero_1 PF11904.3 ETO28008.1 - 6.5e-17 61.6 0.4 6.5e-17 61.6 0.3 3.6 2 2 0 2 2 2 1 GPCR-chaperone Ank PF00023.25 ETO28008.1 - 1.8e-07 30.5 0.0 5.6e-07 29.0 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 ETO28008.1 - 2.1e-07 31.1 0.1 2.5e-06 27.7 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO28008.1 - 3.4e-06 26.7 0.0 2.6e-05 24.0 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat UBA PF00627.26 ETO28008.1 - 0.00012 21.7 0.0 0.00042 20.0 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain Ank_5 PF13857.1 ETO28008.1 - 0.00038 20.5 0.0 0.00083 19.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO28008.1 - 0.0067 16.9 0.0 0.024 15.1 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF2514 PF10721.4 ETO28008.1 - 2.2 7.9 7.0 3.5 7.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) Nucleoplasmin PF03066.10 ETO28012.1 - 0.011 15.2 4.1 0.022 14.2 2.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin Sporozoite_P67 PF05642.6 ETO28012.1 - 0.12 10.1 3.9 0.21 9.4 2.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2489 PF10675.4 ETO28012.1 - 0.31 10.7 0.0 0.31 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) RNA_pol_Rpb4 PF03874.11 ETO28013.1 - 9.5e-09 35.2 0.4 2.1e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb4 SAM_2 PF07647.12 ETO28014.1 - 0.0051 16.6 0.1 0.031 14.1 0.0 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Med28 PF11594.3 ETO28014.1 - 1.4 9.2 7.8 1.2 9.4 0.9 2.8 3 0 0 3 3 3 0 Mediator complex subunit 28 PARG_cat PF05028.9 ETO28015.1 - 4.7e-14 52.3 0.5 6.5e-14 51.9 0.4 1.2 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) PARG_cat PF05028.9 ETO28016.1 - 1.8e-56 191.8 2.0 2.3e-56 191.4 1.4 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) Mito_carr PF00153.22 ETO28018.1 - 7e-14 51.3 0.7 1.4e-06 27.9 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein GCHY-1 PF02649.9 ETO28019.1 - 0.038 13.2 0.0 0.31 10.2 0.0 1.9 1 1 1 2 2 2 0 Type I GTP cyclohydrolase folE2 MIP-T3 PF10243.4 ETO28020.1 - 3e-16 58.9 14.0 3.3e-16 58.8 9.7 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 TPR_11 PF13414.1 ETO28021.1 - 1e-09 37.9 2.9 1.3e-07 31.1 0.2 2.5 1 1 1 2 2 2 2 TPR repeat TPR_12 PF13424.1 ETO28021.1 - 1.2e-06 28.3 0.1 3.1e-06 27.0 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO28021.1 - 1.5e-06 27.5 0.6 0.068 12.8 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO28021.1 - 1e-05 25.0 1.5 0.13 12.2 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO28021.1 - 0.00012 21.6 0.4 0.068 12.9 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO28021.1 - 0.00024 21.4 0.0 0.089 13.4 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO28021.1 - 0.001 19.6 0.0 0.0022 18.6 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO28021.1 - 0.02 15.2 0.0 0.88 9.9 0.0 2.3 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 ETO28021.1 - 0.041 13.7 0.0 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETO28021.1 - 0.13 12.1 0.4 21 5.2 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO28021.1 - 0.31 11.5 3.0 1.5 9.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Thiolase_N PF00108.18 ETO28022.1 - 4.8e-68 229.0 0.1 8.8e-51 172.4 0.0 2.1 1 1 1 2 2 2 2 Thiolase, N-terminal domain Thiolase_C PF02803.13 ETO28022.1 - 5.3e-44 148.5 0.1 8.5e-44 147.9 0.1 1.3 1 0 0 1 1 1 1 Thiolase, C-terminal domain Kelch_1 PF01344.20 ETO28023.1 - 4.5e-06 26.0 0.2 0.19 11.3 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO28023.1 - 0.00015 21.7 1.5 0.18 12.0 0.1 4.2 4 1 1 5 5 5 1 Kelch motif Kelch_2 PF07646.10 ETO28023.1 - 0.0043 16.7 1.9 1.1 9.0 0.1 3.2 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO28023.1 - 0.011 15.6 0.1 7 6.7 0.1 3.5 3 0 0 3 3 3 0 Kelch motif Bap31 PF05529.7 ETO28023.1 - 4.8 6.5 9.1 8.1 5.8 6.3 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like WD40 PF00400.27 ETO28024.1 - 2.9e-81 264.7 18.0 6.3e-13 48.0 0.0 7.0 7 0 0 7 7 7 7 WD domain, G-beta repeat PD40 PF07676.7 ETO28024.1 - 1.7e-07 30.7 9.9 1.6 8.4 0.0 5.5 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO28024.1 - 6e-07 27.9 12.6 0.0087 14.2 0.2 5.4 1 1 5 6 6 6 2 Nucleoporin Nup120/160 DUF1258 PF06869.7 ETO28024.1 - 3.9e-05 22.8 1.2 1 8.4 0.1 4.2 2 2 2 4 4 4 2 Protein of unknown function (DUF1258) Nbas_N PF15492.1 ETO28024.1 - 0.00011 21.4 0.7 1.5 7.8 0.0 3.9 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Gmad1 PF10647.4 ETO28024.1 - 0.00011 21.6 0.0 0.00082 18.8 0.0 2.2 3 0 0 3 3 3 1 Lipoprotein LpqB beta-propeller domain Proteasome_A_N PF10584.4 ETO28024.1 - 0.0005 19.3 4.1 3.3 7.1 0.0 4.9 5 0 0 5 5 5 2 Proteasome subunit A N-terminal signature Cytochrom_D1 PF02239.11 ETO28024.1 - 0.0008 17.8 1.7 0.91 7.7 0.1 3.1 2 1 1 3 3 3 2 Cytochrome D1 heme domain Mid2 PF04478.7 ETO28024.1 - 0.0015 17.9 4.7 0.9 8.9 0.4 3.8 2 1 2 4 4 4 2 Mid2 like cell wall stress sensor BBS2_Mid PF14783.1 ETO28024.1 - 0.0022 17.7 4.0 19 5.0 0.1 4.7 3 1 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 ETO28024.1 - 0.0037 16.0 11.1 6 5.4 7.1 4.6 1 1 1 2 2 2 1 Nup133 N terminal like DUF2527 PF10736.4 ETO28024.1 - 0.0053 16.3 2.1 1.6 8.4 0.1 4.2 4 0 0 4 4 4 1 Protein of unknown function (DUF2627) DPPIV_N PF00930.16 ETO28024.1 - 0.014 14.0 0.0 0.32 9.5 0.0 2.9 2 1 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF1797 PF08796.5 ETO28024.1 - 0.02 14.7 0.0 3.2 7.6 0.0 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1797) HARP PF07443.8 ETO28024.1 - 0.021 14.2 0.4 8.1 5.9 0.0 3.9 5 0 0 5 5 5 0 HepA-related protein (HARP) Resistin PF06954.6 ETO28024.1 - 0.059 13.6 2.7 27 5.1 0.0 4.5 2 2 4 6 6 6 0 Resistin Pkinase PF00069.20 ETO28025.1 - 3e-32 111.7 0.0 4.5e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO28025.1 - 4.6e-12 45.5 0.0 7.3e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 ETO28025.1 - 0.00099 18.0 0.3 0.0015 17.4 0.2 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.9 ETO28025.1 - 0.0015 17.6 0.1 0.0023 17.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO28025.1 - 0.0018 18.0 0.0 0.003 17.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 ETO28025.1 - 0.0065 15.8 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL G-alpha PF00503.15 ETO28027.1 - 1.7e-18 66.5 6.2 4.5e-15 55.2 0.5 3.3 2 1 0 3 3 3 2 G-protein alpha subunit FAM176 PF14851.1 ETO28028.1 - 0.22 11.1 2.5 0.32 10.6 1.8 1.2 1 0 0 1 1 1 0 FAM176 family cobW PF02492.14 ETO28029.1 - 0.018 14.4 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 ETO28029.1 - 0.032 14.1 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 ETO28029.1 - 0.067 13.5 0.6 0.1 12.8 0.4 1.4 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 ETO28029.1 - 0.089 13.6 0.0 0.15 12.8 0.0 1.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 ETO28029.1 - 0.16 11.0 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Collagen PF01391.13 ETO28029.1 - 0.17 11.4 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) dNK PF01712.14 ETO28030.1 - 1.2e-17 64.2 0.2 1.4e-17 63.9 0.2 1.2 1 0 0 1 1 1 1 Deoxynucleoside kinase Thymidylate_kin PF02223.12 ETO28030.1 - 1.7e-05 24.2 0.1 2.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Thymidylate kinase DASH_Dad4 PF08650.5 ETO28030.1 - 0.039 13.8 1.1 0.53 10.2 0.2 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad4 AAA_33 PF13671.1 ETO28030.1 - 0.055 13.3 0.0 0.12 12.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain Avidin PF01382.12 ETO28031.1 - 0.038 14.2 2.6 0.038 14.2 1.8 2.2 1 1 1 2 2 2 0 Avidin family NIF PF03031.13 ETO28035.1 - 3.4e-13 49.5 0.0 4.7e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase WIYLD PF10440.4 ETO28035.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-binding WIYLD domain SurA_N_2 PF13623.1 ETO28037.1 - 0.0034 17.3 0.3 0.005 16.8 0.2 1.2 1 0 0 1 1 1 1 SurA N-terminal domain InvH PF04741.7 ETO28037.1 - 0.099 12.4 0.9 0.14 11.9 0.2 1.5 1 1 0 1 1 1 0 InvH outer membrane lipoprotein HDC PF02329.11 ETO28037.1 - 0.15 10.6 1.1 4.2 5.9 0.1 2.0 1 1 1 2 2 2 0 Histidine carboxylase PI chain DUF947 PF06102.7 ETO28037.1 - 2.5 7.8 11.8 4.2 7.1 8.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF947) DUF4287 PF14117.1 ETO28038.1 - 0.04 13.6 0.8 0.17 11.5 0.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4287) Tir_receptor_N PF07490.6 ETO28038.1 - 0.18 11.3 1.2 0.29 10.7 0.4 1.6 1 1 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus HECT PF00632.20 ETO28039.1 - 2.2e-11 43.4 0.0 3.5e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Laminin_G_3 PF13385.1 ETO28039.1 - 4.2e-10 40.0 0.0 9.6e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Alb1 PF09135.6 ETO28040.1 - 0.21 12.1 2.8 0.4 11.3 2.0 1.3 1 0 0 1 1 1 0 Alb1 PLRV_ORF5 PF01690.12 ETO28040.1 - 4.4 6.3 10.7 6.5 5.7 7.4 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SSP160 PF06933.6 ETO28041.1 - 1.4 6.7 18.7 1.8 6.4 13.0 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf-RanBP PF00641.13 ETO28042.1 - 3.2e-08 32.5 16.0 2.6e-06 26.4 1.0 3.1 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.2 ETO28042.1 - 0.0011 18.7 6.6 0.53 10.1 0.1 2.4 2 0 0 2 2 2 2 Double zinc ribbon RSN1_TM PF13967.1 ETO28042.1 - 0.0024 17.4 0.2 1.5 8.3 0.0 2.8 2 0 0 2 2 2 2 Late exocytosis, associated with Golgi transport ETRAMP PF09716.5 ETO28042.1 - 0.03 14.2 5.5 0.83 9.6 0.3 3.7 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) 7tm_1 PF00001.16 ETO28042.1 - 0.055 12.5 0.5 1.7 7.7 0.0 2.4 3 0 0 3 3 3 0 7 transmembrane receptor (rhodopsin family) TRP PF06011.7 ETO28042.1 - 0.24 9.9 2.1 1.9 6.9 0.2 2.4 2 1 0 2 2 2 0 Transient receptor potential (TRP) ion channel EphA2_TM PF14575.1 ETO28042.1 - 0.48 10.8 5.2 4.1 7.8 0.0 3.4 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain FancD2 PF14631.1 ETO28042.1 - 0.62 7.0 4.8 0.26 8.3 0.1 2.0 2 0 0 2 2 2 0 Fanconi anaemia protein FancD2 nuclease Kei1 PF08552.6 ETO28042.1 - 2.5 7.7 7.6 0.54 9.8 0.2 2.8 3 0 0 3 3 3 0 Inositolphosphorylceramide synthase subunit Kei1 Zip PF02535.17 ETO28042.1 - 2.8 6.8 7.5 1.5e+02 1.1 5.0 2.7 1 1 0 1 1 1 0 ZIP Zinc transporter Chordopox_A13L PF05961.6 ETO28042.1 - 2.9 7.8 0.0 2.9 7.8 0.0 3.2 3 1 0 3 3 3 0 Chordopoxvirus A13L protein RasGEF PF00617.14 ETO28043.1 - 3.3e-37 128.0 0.5 5.7e-37 127.2 0.4 1.4 1 0 0 1 1 1 1 RasGEF domain CDC37_N PF03234.9 ETO28043.1 - 5.2 7.3 12.0 0.72 10.1 5.1 1.9 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding MFS_2 PF13347.1 ETO28044.1 - 1.4e-07 30.3 4.6 2.4e-07 29.5 3.2 1.3 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.11 ETO28045.1 - 8.4e-10 37.8 0.0 1.5e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily FA_desaturase PF00487.19 ETO28045.1 - 0.031 13.7 2.0 4.5 6.6 0.0 2.2 2 0 0 2 2 2 0 Fatty acid desaturase SNARE_assoc PF09335.6 ETO28045.1 - 0.032 14.4 0.0 0.032 14.4 0.0 2.7 2 1 0 2 2 2 0 SNARE associated Golgi protein PP-binding PF00550.20 ETO28046.1 - 6.7e-11 42.2 0.5 1.2e-10 41.5 0.4 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 ETO28046.1 - 0.00049 20.0 0.2 0.00072 19.5 0.1 1.3 1 0 0 1 1 1 1 Acyl-carrier Chorion_2 PF03964.10 ETO28046.1 - 0.033 14.7 0.6 0.048 14.2 0.4 1.2 1 0 0 1 1 1 0 Chorion family 2 Ribosomal_60s PF00428.14 ETO28046.1 - 0.23 11.8 6.3 0.46 10.9 4.4 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4169 PF13770.1 ETO28046.1 - 4.4 7.3 6.7 8.4 6.4 4.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4169) Ribosomal_L35Ae PF01247.13 ETO28048.1 - 0.059 13.1 1.9 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L35Ae DUF2201_N PF13203.1 ETO28048.1 - 0.43 9.7 12.4 0.7 9.0 8.6 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.9 ETO28048.1 - 6.9 4.5 15.9 10 4.0 11.0 1.2 1 0 0 1 1 1 0 CDC45-like protein XRN_N PF03159.13 ETO28048.1 - 7.4 5.8 10.7 0.22 10.8 2.7 1.9 2 1 1 3 3 3 0 XRN 5'-3' exonuclease N-terminus GTP_EFTU PF00009.22 ETO28049.1 - 2.5e-23 82.5 0.1 3.6e-23 81.9 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 ETO28049.1 - 0.0021 17.3 2.8 0.0052 16.0 1.1 2.2 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU_D2 PF03144.20 ETO28049.1 - 0.0061 16.6 0.1 0.013 15.5 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 ETO28049.1 - 0.011 15.7 0.0 0.029 14.3 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 ETO28049.1 - 0.058 12.9 1.3 0.38 10.2 0.9 2.1 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein Sen15 PF09631.5 ETO28050.1 - 0.11 12.7 0.6 0.3 11.3 0.2 1.9 2 0 0 2 2 2 0 Sen15 protein EamA PF00892.15 ETO28051.1 - 0.033 14.2 9.3 0.033 14.2 4.0 2.2 1 1 1 2 2 2 0 EamA-like transporter family Kei1 PF08552.6 ETO28051.1 - 0.21 11.2 2.1 0.33 10.5 0.4 1.9 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 TPR_1 PF00515.23 ETO28053.1 - 9.9e-06 24.9 0.0 3.7e-05 23.1 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO28053.1 - 1e-05 25.0 0.0 3.8e-05 23.2 0.0 2.0 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 ETO28053.1 - 1.4e-05 24.6 0.0 6.9e-05 22.4 0.0 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO28053.1 - 0.00038 20.3 0.0 0.0013 18.6 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO28053.1 - 0.00064 19.7 0.0 0.0036 17.3 0.0 2.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO28053.1 - 0.0018 17.9 0.0 0.012 15.3 0.0 2.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO28053.1 - 0.0028 17.3 0.0 0.018 14.7 0.0 2.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO28053.1 - 0.0062 17.1 0.0 0.017 15.8 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO28053.1 - 0.13 12.9 0.0 0.96 10.2 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TLD PF07534.11 ETO28055.1 - 1.7e-14 54.0 3.9 4.3e-14 52.6 2.7 1.7 1 0 0 1 1 1 1 TLD fn3 PF00041.16 ETO28055.1 - 0.018 15.1 0.0 0.078 13.1 0.0 2.2 1 0 0 1 1 1 0 Fibronectin type III domain SgrR_N PF12793.2 ETO28055.1 - 0.058 13.3 0.1 0.058 13.3 0.1 2.1 2 0 0 2 2 2 0 Sugar transport-related sRNA regulator N-term Abhydrolase_6 PF12697.2 ETO28056.1 - 1.4e-24 87.2 0.0 1.7e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETO28056.1 - 4.4e-14 52.4 0.0 1.1e-13 51.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 ETO28056.1 - 5.8e-09 35.7 0.1 0.0016 17.9 0.2 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 ETO28056.1 - 4.1e-08 33.0 0.8 0.00046 19.8 0.1 3.1 2 1 0 2 2 2 2 alpha/beta hydrolase fold DUF2305 PF10230.4 ETO28056.1 - 0.0019 17.6 0.5 0.012 15.0 0.3 2.2 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Hydrolase_4 PF12146.3 ETO28056.1 - 0.0021 17.8 0.0 0.005 16.6 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 ETO28056.1 - 0.0091 15.2 0.0 0.077 12.1 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Ser_hydrolase PF06821.8 ETO28056.1 - 0.011 15.3 0.0 0.064 12.8 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase Lipase_3 PF01764.20 ETO28056.1 - 0.016 14.8 0.0 0.042 13.4 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Chromo_shadow PF01393.14 ETO28056.1 - 0.047 13.5 1.2 0.13 12.1 0.1 2.2 2 0 0 2 2 2 0 Chromo shadow domain AbiH PF14253.1 ETO28056.1 - 1.4 8.4 9.1 1.4 8.4 3.1 2.6 2 1 1 3 3 3 0 Bacteriophage abortive infection AbiH MSC PF09402.5 ETO28058.1 - 0.069 11.8 0.8 0.15 10.7 0.5 1.6 1 1 0 1 1 1 0 Man1-Src1p-C-terminal domain DUF912 PF06024.7 ETO28058.1 - 7.1 6.7 7.4 45 4.1 4.1 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Senescence_reg PF04520.8 ETO28059.1 - 0.76 10.2 9.4 0.96 9.9 6.5 1.3 1 0 0 1 1 1 0 Senescence regulator Ebola_NP PF05505.7 ETO28059.1 - 5.1 5.0 23.0 5.6 4.9 16.0 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein Androgen_recep PF02166.11 ETO28059.1 - 6.1 5.5 10.3 6.6 5.4 7.1 1.2 1 0 0 1 1 1 0 Androgen receptor FLO_LFY PF01698.11 ETO28059.1 - 9 5.0 12.4 10 4.8 8.6 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein HAD_2 PF13419.1 ETO28060.1 - 1.6e-05 25.1 0.0 2.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Menin PF05053.8 ETO28060.1 - 0.33 9.0 11.5 0.4 8.7 8.0 1.2 1 0 0 1 1 1 0 Menin Macoilin PF09726.4 ETO28060.1 - 8.3 4.5 18.1 10 4.2 12.5 1.2 1 0 0 1 1 1 0 Transmembrane protein Peptidase_M1 PF01433.15 ETO28061.1 - 1.9e-66 224.7 0.8 2.1e-66 224.6 0.6 1.0 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 ETO28061.1 - 4e-14 52.7 0.4 5.6e-14 52.2 0.3 1.2 1 0 0 1 1 1 1 Peptidase MA superfamily DUF2265 PF10023.4 ETO28061.1 - 0.0065 15.6 0.1 0.0097 15.0 0.0 1.2 1 0 0 1 1 1 1 Predicted aminopeptidase (DUF2265) zf-C3HC4_3 PF13920.1 ETO28062.1 - 2.1e-12 46.5 13.3 3.1e-12 45.9 9.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO28062.1 - 2.7e-05 24.0 17.1 5.5e-05 23.1 11.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO28062.1 - 0.0017 17.9 14.5 0.0021 17.6 8.8 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO28062.1 - 0.0044 16.7 14.3 0.0082 15.8 9.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain C1_2 PF03107.11 ETO28062.1 - 0.0095 16.0 0.6 0.0095 16.0 0.4 2.5 3 0 0 3 3 3 1 C1 domain Menin PF05053.8 ETO28062.1 - 0.26 9.3 3.9 0.26 9.4 2.7 1.1 1 0 0 1 1 1 0 Menin zf-RING_2 PF13639.1 ETO28062.1 - 0.66 9.8 14.0 1.1 9.0 9.7 1.4 1 0 0 1 1 1 0 Ring finger domain G-alpha PF00503.15 ETO28063.1 - 2.8e-30 105.3 1.6 3.4e-30 105.0 1.1 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO28063.1 - 2e-05 23.9 0.1 4.7e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family Kri1 PF05178.7 ETO28063.1 - 3.1 8.1 11.4 5.6 7.3 0.0 2.4 2 1 0 2 2 2 0 KRI1-like family Cation_efflux PF01545.16 ETO28064.1 - 4.7e-26 91.4 13.6 6e-26 91.1 9.4 1.1 1 0 0 1 1 1 1 Cation efflux family ABC2_membrane_5 PF13346.1 ETO28064.1 - 0.2 10.8 12.2 0.025 13.8 4.8 1.9 1 1 0 2 2 2 0 ABC-2 family transporter protein G-alpha PF00503.15 ETO28065.1 - 2e-14 53.1 8.6 1.1e-12 47.3 1.0 4.1 1 1 2 3 3 3 2 G-protein alpha subunit DUF3439 PF11921.3 ETO28065.1 - 0.043 13.5 3.0 0.11 12.2 2.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) YwpF PF14183.1 ETO28065.1 - 0.057 13.1 0.3 0.057 13.1 0.2 1.9 2 0 0 2 2 2 0 YwpF-like protein Rubella_E2 PF05749.6 ETO28065.1 - 0.19 10.9 0.3 0.28 10.3 0.2 1.2 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 POP1 PF06978.6 ETO28065.1 - 0.23 11.1 3.7 0.12 12.0 0.6 1.9 2 1 0 2 2 2 0 Ribonucleases P/MRP protein subunit POP1 MTBP_mid PF14919.1 ETO28066.1 - 0.018 13.7 0.1 0.022 13.4 0.1 1.3 1 0 0 1 1 1 0 MDM2-binding Cation_efflux PF01545.16 ETO28067.1 - 3.4e-35 121.5 1.2 6.5e-35 120.5 0.8 1.4 1 0 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.11 ETO28067.1 - 0.4 9.6 6.3 2.8 6.8 0.1 2.6 3 0 0 3 3 3 0 Branched-chain amino acid transport system / permease component 2OG-FeII_Oxy_3 PF13640.1 ETO28068.1 - 0.0024 18.3 0.0 0.0071 16.8 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 ETO28068.1 - 0.051 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF621 PF04789.10 ETO28068.1 - 0.12 11.3 0.1 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF621) Skp1 PF01466.14 ETO28069.1 - 0.004 17.1 0.0 0.015 15.3 0.0 2.0 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Dzip-like_N PF13815.1 ETO28070.1 - 0.0033 17.2 1.2 0.0033 17.2 0.8 1.7 2 0 0 2 2 2 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal LLC1 PF14945.1 ETO28070.1 - 0.0066 16.7 1.5 0.0094 16.2 1.0 1.4 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein DUF3807 PF12720.2 ETO28070.1 - 0.033 14.3 6.9 0.049 13.7 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF3635 PF12330.3 ETO28070.1 - 0.034 14.2 0.1 0.078 13.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3635) Sporozoite_P67 PF05642.6 ETO28070.1 - 0.047 11.5 8.0 0.057 11.2 5.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PI3K_1B_p101 PF10486.4 ETO28070.1 - 0.13 9.7 5.9 0.15 9.5 4.1 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit BSP_II PF05432.6 ETO28070.1 - 0.24 10.6 13.8 0.38 10.0 9.6 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF2457 PF10446.4 ETO28070.1 - 0.28 9.8 15.5 0.38 9.4 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 ETO28070.1 - 0.43 9.0 13.0 0.56 8.6 9.0 1.2 1 0 0 1 1 1 0 Daxx Family VirE2 PF07229.7 ETO28070.1 - 0.64 8.3 5.5 0.83 7.9 3.8 1.1 1 0 0 1 1 1 0 VirE2 DUF3381 PF11861.3 ETO28070.1 - 0.7 9.3 13.1 0.34 10.4 7.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) RNA_pol_3_Rpc31 PF11705.3 ETO28070.1 - 1.1 9.1 15.5 0.13 12.1 7.3 1.8 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Nucleoplasmin PF03066.10 ETO28070.1 - 1.2 8.6 12.9 0.35 10.3 5.5 2.2 2 0 0 2 2 2 0 Nucleoplasmin RabGAP-TBC PF00566.13 ETO28070.1 - 2.7 7.3 5.5 0.82 9.0 1.8 1.5 2 0 0 2 2 2 0 Rab-GTPase-TBC domain Nop53 PF07767.6 ETO28070.1 - 3.6 6.4 15.9 6.5 5.6 11.0 1.4 1 1 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) BUD22 PF09073.5 ETO28070.1 - 4.3 6.3 16.0 5.5 5.9 11.1 1.1 1 0 0 1 1 1 0 BUD22 Bap31 PF05529.7 ETO28070.1 - 4.8 6.6 6.7 14 5.1 3.5 2.0 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like ANAPC15 PF15243.1 ETO28070.1 - 7.5 6.7 18.7 3 7.9 8.8 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 DUF1014 PF06244.7 ETO28070.1 - 8.7 6.5 14.1 46 4.2 8.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) Peptidase_S49_N PF08496.5 ETO28071.1 - 4.1 7.1 7.6 18 5.0 3.1 2.0 1 1 1 2 2 2 0 Peptidase family S49 N-terminal Coat_X PF07552.6 ETO28072.1 - 0.096 12.4 0.3 3.8 7.3 0.0 2.6 2 0 0 2 2 2 0 Spore Coat Protein X and V domain Afi1 PF07792.7 ETO28073.1 - 0.02 14.8 1.6 0.036 14.0 1.1 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking AT_hook PF02178.14 ETO28074.1 - 0.32 10.7 4.4 0.69 9.7 3.0 1.6 1 0 0 1 1 1 0 AT hook motif CHAT PF12770.2 ETO28075.1 - 1.9e-06 27.2 0.0 0.00017 20.8 0.0 2.4 1 1 0 2 2 2 2 CHAT domain NB-ARC PF00931.17 ETO28075.1 - 6.8e-06 25.1 2.3 0.0017 17.2 0.0 3.5 3 0 0 3 3 3 2 NB-ARC domain NACHT PF05729.7 ETO28075.1 - 4e-05 23.3 0.1 0.00045 19.9 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 ETO28075.1 - 0.11 12.4 0.1 0.59 10.0 0.1 2.4 1 1 0 1 1 1 0 AAA ATPase domain Pkinase PF00069.20 ETO28076.1 - 5.9e-16 58.3 0.0 7e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO28076.1 - 0.0026 16.8 0.0 0.0033 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UCH PF00443.24 ETO28077.1 - 1.4e-39 135.8 4.4 1.4e-39 135.8 3.1 2.3 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO28077.1 - 1.5e-13 50.8 5.3 1.5e-13 50.8 3.7 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase PPR_3 PF13812.1 ETO28081.1 - 1.1e-05 25.2 1.1 23 5.5 0.0 5.9 6 0 0 6 6 6 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 ETO28081.1 - 1.1e-05 25.2 5.3 15 5.6 0.0 6.4 6 1 0 6 6 6 3 PPR repeat family PPR PF01535.15 ETO28081.1 - 0.0018 18.0 1.1 31 4.8 0.0 5.0 4 1 0 4 4 4 0 PPR repeat TPR_12 PF13424.1 ETO28081.1 - 0.055 13.4 0.0 11 6.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C3Hc3H PF13891.1 ETO28081.1 - 0.85 9.7 7.3 0.83 9.7 0.1 3.2 3 0 0 3 3 3 0 Potential DNA-binding domain gpUL132 PF11359.3 ETO28082.1 - 0.0081 15.5 0.0 0.0084 15.4 0.0 1.2 1 0 0 1 1 1 1 Glycoprotein UL132 Pox_P21 PF05313.7 ETO28082.1 - 0.025 13.8 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Poxvirus P21 membrane protein Sulfotransfer_3 PF13469.1 ETO28083.1 - 0.002 19.0 5.5 0.0054 17.6 3.8 1.7 1 1 0 1 1 1 1 Sulfotransferase family MBOAT_2 PF13813.1 ETO28083.1 - 0.023 14.7 1.6 0.056 13.5 1.1 1.6 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family Dus PF01207.12 ETO28084.1 - 6.4e-54 182.8 1.0 8.5e-54 182.4 0.7 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 ETO28084.1 - 0.00045 19.5 0.0 0.00096 18.4 0.0 1.5 1 1 0 1 1 1 1 Histidine biosynthesis protein TMP-TENI PF02581.12 ETO28084.1 - 0.023 13.7 0.0 0.095 11.8 0.0 1.9 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI DUF849 PF05853.7 ETO28084.1 - 0.029 13.2 0.0 0.046 12.6 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic protein of unknown function (DUF849) DHO_dh PF01180.16 ETO28084.1 - 0.17 10.8 0.1 3.5 6.4 0.0 2.1 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase TSNR_N PF04705.7 ETO28086.1 - 0.055 13.2 0.1 0.1 12.3 0.1 1.4 1 0 0 1 1 1 0 Thiostrepton-resistance methylase, N terminus Arm PF00514.18 ETO28087.1 - 6.7e-10 38.4 0.1 6.5e-05 22.6 0.0 3.4 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 ETO28087.1 - 0.00039 20.8 0.0 0.0015 18.9 0.0 1.9 2 0 0 2 2 2 1 HEAT-like repeat Daxx PF03344.10 ETO28087.1 - 0.09 11.2 8.4 0.098 11.1 5.8 1.1 1 0 0 1 1 1 0 Daxx Family TRAP_alpha PF03896.11 ETO28087.1 - 0.16 10.9 4.3 0.19 10.7 3.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PH_10 PF15411.1 ETO28087.1 - 0.41 10.8 2.6 0.46 10.6 0.4 1.9 1 1 1 2 2 2 0 Pleckstrin homology domain Tom37_C PF11801.3 ETO28087.1 - 1.2 8.9 4.3 1.3 8.9 2.0 1.6 2 0 0 2 2 2 0 Tom37 C-terminal domain Tom22 PF04281.8 ETO28087.1 - 1.4 8.3 7.2 2.2 7.8 5.0 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 RXT2_N PF08595.6 ETO28087.1 - 2.1 8.1 12.3 3.4 7.4 8.5 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Pox_RNA_Pol_19 PF05320.7 ETO28087.1 - 2.1 8.0 8.8 1.1 8.9 4.9 1.4 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Sigma70_ner PF04546.8 ETO28087.1 - 2.4 7.7 14.7 3.6 7.1 10.2 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region RRN3 PF05327.6 ETO28087.1 - 2.4 6.1 6.6 2.9 5.9 4.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pox_Ag35 PF03286.9 ETO28087.1 - 3.8 6.9 12.9 1.3 8.4 7.0 1.6 2 0 0 2 2 2 0 Pox virus Ag35 surface protein FAM176 PF14851.1 ETO28087.1 - 4.6 6.9 8.1 7.2 6.2 5.6 1.4 1 0 0 1 1 1 0 FAM176 family RNA_pol_Rpc4 PF05132.9 ETO28087.1 - 4.9 7.1 8.9 8.2 6.4 6.1 1.7 1 1 0 1 1 1 0 RNA polymerase III RPC4 DUF2457 PF10446.4 ETO28087.1 - 5.7 5.5 19.2 7 5.2 13.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CobT PF06213.7 ETO28087.1 - 8.3 5.4 15.0 11 5.0 10.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT MIP-T3 PF10243.4 ETO28088.1 - 0.00056 18.5 53.6 0.00074 18.1 37.2 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF1777 PF08648.7 ETO28088.1 - 0.0075 16.0 90.7 0.23 11.1 38.9 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1777) RRM_6 PF14259.1 ETO28089.1 - 2.7e-08 33.6 0.0 6.6e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO28089.1 - 1.4e-07 31.0 0.1 3e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SSP160 PF06933.6 ETO28089.1 - 6.1 4.6 16.2 8.9 4.1 11.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RRM_1 PF00076.17 ETO28090.1 - 7.1e-15 54.4 0.0 1.4e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO28090.1 - 4.4e-12 45.8 0.0 8e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO28090.1 - 1.7e-05 24.5 4.4 1.8e-05 24.4 0.0 2.6 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 ETO28090.1 - 0.00085 19.0 0.1 0.0021 17.7 0.1 1.7 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 ETO28090.1 - 0.021 14.5 0.1 0.051 13.3 0.0 1.6 2 0 0 2 2 2 0 Limkain b1 Nup35_RRM_2 PF14605.1 ETO28090.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.17 ETO28091.1 - 3.2e-20 71.5 0.0 5.3e-17 61.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO28091.1 - 9.9e-17 60.6 0.0 1.1e-12 47.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO28091.1 - 3.6e-10 39.5 0.0 1.2e-09 37.8 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF956 PF06115.6 ETO28091.1 - 0.048 13.2 0.0 0.35 10.4 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF956) DUF3852 PF12963.2 ETO28091.1 - 0.092 12.7 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3852) F-box-like PF12937.2 ETO28093.1 - 0.0037 16.9 0.0 0.017 14.8 0.0 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETO28093.1 - 0.066 12.8 1.0 0.32 10.6 0.0 2.6 3 0 0 3 3 3 0 F-box domain LRR_8 PF13855.1 ETO28093.1 - 0.13 12.0 1.5 14 5.5 0.3 2.8 2 0 0 2 2 2 0 Leucine rich repeat Ribosomal_S28e PF01200.13 ETO28095.1 - 9.6e-25 86.1 0.2 1.2e-24 85.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e HSP70 PF00012.15 ETO28096.1 - 7.7e-94 314.7 17.9 2.5e-84 283.2 0.1 3.1 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 ETO28096.1 - 1e-05 24.2 0.0 0.0001 21.0 0.0 2.4 3 0 0 3 3 3 1 MreB/Mbl protein DUF1510 PF07423.6 ETO28096.1 - 7.8 5.8 23.2 0.14 11.5 10.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) HSP70 PF00012.15 ETO28097.1 - 1.4e-07 29.8 0.9 1.4e-07 29.8 0.7 2.2 2 1 1 3 3 3 1 Hsp70 protein DUF2360 PF10152.4 ETO28097.1 - 0.014 15.7 4.3 0.023 14.9 3.0 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) FAP PF07174.6 ETO28097.1 - 4.6 6.4 10.3 6.4 5.9 7.2 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF948 PF06103.6 ETO28098.1 - 0.12 12.2 0.7 1.8 8.4 0.0 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) EF-hand_1 PF00036.27 ETO28099.1 - 0.056 12.7 0.5 0.27 10.6 0.0 2.1 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.1 ETO28099.1 - 0.11 12.6 0.5 0.3 11.2 0.3 1.8 1 1 0 1 1 1 0 EF-hand domain pair LRR_8 PF13855.1 ETO28100.1 - 3e-06 26.8 0.2 0.0012 18.5 0.2 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 ETO28100.1 - 0.00045 19.7 0.9 0.0084 15.7 0.4 2.8 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) CDC45 PF02724.9 ETO28102.1 - 0.0022 16.0 9.1 0.0022 16.1 6.3 1.1 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.7 ETO28102.1 - 0.015 14.5 14.6 0.017 14.4 10.1 1.1 1 0 0 1 1 1 0 SDA1 Tim54 PF11711.3 ETO28102.1 - 0.13 10.7 3.5 0.18 10.3 2.5 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Daxx PF03344.10 ETO28102.1 - 0.15 10.4 19.1 0.19 10.1 13.2 1.1 1 0 0 1 1 1 0 Daxx Family Hid1 PF12722.2 ETO28102.1 - 0.36 8.4 4.9 0.33 8.5 3.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Prothymosin PF03247.9 ETO28102.1 - 0.77 9.9 38.0 0.062 13.4 22.9 1.6 2 0 0 2 2 2 0 Prothymosin/parathymosin family Nop14 PF04147.7 ETO28102.1 - 0.86 7.4 25.4 1.1 7.0 17.6 1.1 1 0 0 1 1 1 0 Nop14-like family GOLD_2 PF13897.1 ETO28102.1 - 2.6 8.2 6.9 4.1 7.6 4.8 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking DUF1510 PF07423.6 ETO28102.1 - 4.6 6.5 16.4 6.4 6.0 11.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PABP PF00658.13 ETO28103.1 - 1.9e-08 33.8 0.0 3.3e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain DUF2201_N PF13203.1 ETO28103.1 - 0.051 12.7 1.1 0.067 12.3 0.7 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain BTV_NS2 PF04514.7 ETO28103.1 - 0.073 11.9 3.2 0.11 11.3 2.2 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Nop14 PF04147.7 ETO28103.1 - 0.55 8.0 15.6 0.66 7.8 10.8 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 ETO28103.1 - 0.65 8.4 12.1 0.86 8.0 8.4 1.2 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 ETO28103.1 - 0.68 7.9 5.9 0.79 7.6 4.1 1.1 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.6 ETO28103.1 - 1.6 8.1 14.0 2.2 7.7 9.7 1.2 1 0 0 1 1 1 0 PPP4R2 Cwf_Cwc_15 PF04889.7 ETO28103.1 - 1.6 8.3 14.5 2.3 7.8 10.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PTB PF08416.8 ETO28105.1 - 0.094 12.6 0.1 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Phosphotyrosine-binding domain PgaD PF13994.1 ETO28106.1 - 0.52 9.7 2.5 6.3 6.2 0.0 2.9 2 1 1 3 3 3 0 PgaD-like protein Synaptobrevin PF00957.16 ETO28107.1 - 3.3e-09 36.2 0.2 1e-08 34.6 0.1 1.9 1 0 0 1 1 1 1 Synaptobrevin Myco_19_kDa PF05481.7 ETO28107.1 - 0.15 11.8 0.2 0.15 11.8 0.1 1.9 2 0 0 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen KH_3 PF13014.1 ETO28108.1 - 0.12 12.0 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 KH domain Sulfate_transp PF00916.15 ETO28109.1 - 6e-23 81.2 0.2 1.2e-22 80.3 0.1 1.4 1 0 0 1 1 1 1 Sulfate transporter family Tmemb_170 PF10190.4 ETO28109.1 - 5.4 7.1 8.0 26 4.9 0.0 3.3 2 1 1 3 3 3 0 Putative transmembrane protein 170 Ras PF00071.17 ETO28110.1 - 1.3e-38 131.9 5.2 2.4e-28 98.5 2.5 3.1 1 1 1 2 2 2 2 Ras family Miro PF08477.8 ETO28110.1 - 1.1e-16 61.3 0.0 3e-16 59.9 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein PsaD PF02531.11 ETO28110.1 - 0.0048 16.1 0.8 2.1 7.5 0.1 2.3 2 0 0 2 2 2 2 PsaD DUF258 PF03193.11 ETO28110.1 - 0.047 12.8 0.1 0.14 11.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Arf PF00025.16 ETO28110.1 - 0.054 12.7 0.2 4.8 6.3 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF384 PF04064.8 ETO28110.1 - 0.069 12.7 0.1 0.38 10.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF384) PC-Esterase PF13839.1 ETO28110.1 - 0.073 12.8 1.9 0.17 11.6 1.3 1.7 1 1 1 2 2 2 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p AAA_10 PF12846.2 ETO28110.1 - 0.12 11.8 0.2 0.23 10.8 0.1 1.6 1 1 0 1 1 1 0 AAA-like domain ScpA_ScpB PF02616.9 ETO28112.1 - 1.2 8.6 13.0 1.3 8.5 9.0 1.1 1 0 0 1 1 1 0 ScpA/B protein DUF763 PF05559.6 ETO28112.1 - 3 6.6 6.8 3.3 6.5 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF763) HAUS6_N PF14661.1 ETO28112.1 - 7.4 5.8 13.8 8.3 5.6 9.5 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF1523 PF07509.6 ETO28113.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1523) DUF106 PF01956.11 ETO28113.1 - 1.7 8.1 7.6 0.96 8.9 3.6 1.7 2 0 0 2 2 2 0 Integral membrane protein DUF106 SHQ1 PF04925.10 ETO28115.1 - 0.00041 19.8 0.2 0.00077 18.9 0.1 1.4 1 0 0 1 1 1 1 SHQ1 protein Med19 PF10278.4 ETO28116.1 - 0.59 9.7 14.5 0.79 9.3 10.1 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 CDK5_activator PF03261.10 ETO28116.1 - 0.95 8.7 8.2 1 8.6 5.7 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Spc24 PF08286.6 ETO28117.1 - 0.17 11.6 3.3 0.29 10.8 2.3 1.5 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 RRM_1 PF00076.17 ETO28118.1 - 1.1e-39 133.8 11.2 8.1e-18 63.8 0.3 4.4 5 1 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO28118.1 - 5.3e-28 96.7 6.2 2.5e-13 49.7 0.2 4.0 3 1 1 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO28118.1 - 1e-27 95.7 0.5 2.6e-13 49.5 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETO28118.1 - 4.6e-05 23.1 1.4 3 7.6 0.0 3.7 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 ETO28118.1 - 0.00022 21.0 12.7 0.38 10.6 0.1 4.4 4 0 0 4 4 4 3 RNA binding motif SET_assoc PF11767.3 ETO28118.1 - 0.01 15.1 2.0 1.1 8.6 0.0 3.5 4 0 0 4 4 4 0 Histone lysine methyltransferase SET associated Guanylate_cyc PF00211.15 ETO28118.1 - 0.049 13.0 0.5 0.09 12.1 0.4 1.4 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain Cauli_DNA-bind PF03310.8 ETO28118.1 - 0.076 12.8 1.5 0.17 11.7 1.0 1.5 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein DUF4101 PF13355.1 ETO28118.1 - 0.24 11.8 10.6 0.54 10.6 7.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4101) AAA_23 PF13476.1 ETO28118.1 - 3.6 7.8 14.7 6.9 6.9 10.1 1.6 1 1 0 1 1 1 0 AAA domain DUF607 PF04678.8 ETO28118.1 - 4.6 7.1 9.6 2.2 8.1 4.6 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF607 Bac_small_YrzI PF09501.5 ETO28119.1 - 1.4 8.9 4.1 2.5 8.0 2.8 1.4 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) Pribosyltran PF00156.22 ETO28120.1 - 0.077 12.7 0.2 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase domain DUF2222 PF09984.4 ETO28120.1 - 0.079 12.3 0.7 0.12 11.8 0.5 1.2 1 0 0 1 1 1 0 Uncharacterized signal transduction histidine kinase domain (DUF2222) TMEM240 PF15207.1 ETO28120.1 - 0.16 11.5 0.3 0.23 11.0 0.2 1.3 1 0 0 1 1 1 0 TMEM240 family Pox_polyA_pol_N PF12630.2 ETO28122.1 - 0.048 13.7 3.7 0.19 11.8 0.5 2.5 2 0 0 2 2 2 0 Poxvirus poly(A) polymerase N-terminal domain Ig_J_chain PF15097.1 ETO28125.1 - 0.027 14.0 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin J chain DUF569 PF04601.8 ETO28126.1 - 0.14 11.5 0.1 0.52 9.7 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF569) VWA_2 PF13519.1 ETO28127.1 - 5.4e-15 55.9 0.0 8e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain SAP PF02037.22 ETO28127.1 - 1.4e-05 24.4 0.2 1.4e-05 24.4 0.2 2.3 3 0 0 3 3 3 1 SAP domain PADR1 PF08063.7 ETO28127.1 - 5.9e-05 22.3 6.8 5.9e-05 22.3 4.7 2.5 2 1 0 2 2 2 1 PADR1 (NUC008) domain Acyl_transf_3 PF01757.17 ETO28128.1 - 0.021 13.6 0.3 0.027 13.3 0.2 1.1 1 0 0 1 1 1 0 Acyltransferase family GtrA PF04138.9 ETO28128.1 - 0.054 13.4 1.2 0.085 12.8 0.8 1.2 1 0 0 1 1 1 0 GtrA-like protein Daxx PF03344.10 ETO28128.1 - 0.076 11.4 18.0 0.096 11.1 12.4 1.1 1 0 0 1 1 1 0 Daxx Family VIT1 PF01988.14 ETO28128.1 - 0.2 11.1 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 VIT family CDC45 PF02724.9 ETO28128.1 - 0.21 9.5 14.6 0.28 9.1 10.1 1.3 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.27 ETO28129.1 - 1.1e-20 72.6 0.2 2.6e-09 36.6 0.1 2.8 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO28129.1 - 3.6e-05 22.0 0.6 0.0052 14.9 0.1 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO28129.1 - 0.00061 18.6 3.4 0.0079 14.9 2.3 2.1 1 1 0 1 1 1 1 Nup133 N terminal like Cu-oxidase_2 PF07731.9 ETO28129.1 - 0.16 11.4 0.7 0.32 10.5 0.5 1.7 1 1 0 1 1 1 0 Multicopper oxidase XhlA PF10779.4 ETO28129.1 - 9 6.2 9.8 18 5.3 6.8 1.5 1 0 0 1 1 1 0 Haemolysin XhlA VWA_3 PF13768.1 ETO28130.1 - 9.3e-11 41.6 0.0 9.7e-10 38.3 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.1 ETO28130.1 - 2.6e-06 27.6 0.0 4.5e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1102 PF06510.6 ETO28130.1 - 0.023 14.5 0.1 0.058 13.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1102) VWA PF00092.23 ETO28130.1 - 0.085 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain WD40 PF00400.27 ETO28131.1 - 5.6e-06 26.0 4.0 0.021 14.7 0.2 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat V-SNARE_C PF12352.3 ETO28133.1 - 8e-10 38.6 3.0 1e-09 38.3 2.1 1.2 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 ETO28133.1 - 5.3e-07 29.2 0.2 6.8e-07 28.9 0.1 1.1 1 0 0 1 1 1 1 Sec20 Laminin_II PF06009.7 ETO28133.1 - 0.0029 17.3 1.3 0.0042 16.8 0.9 1.1 1 0 0 1 1 1 1 Laminin Domain II Herpes_US9 PF06072.6 ETO28133.1 - 0.0034 17.1 0.6 0.0062 16.3 0.4 1.4 1 0 0 1 1 1 1 Alphaherpesvirus tegument protein US9 Tropomyosin_1 PF12718.2 ETO28133.1 - 0.013 15.3 2.8 0.016 15.0 1.9 1.1 1 0 0 1 1 1 0 Tropomyosin like EMP24_GP25L PF01105.19 ETO28133.1 - 0.018 14.7 1.0 0.021 14.5 0.7 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD SNARE PF05739.14 ETO28133.1 - 0.018 14.7 2.8 0.028 14.0 2.0 1.4 1 1 0 1 1 1 0 SNARE domain DUF2254 PF10011.4 ETO28133.1 - 0.033 12.6 1.8 0.039 12.4 0.4 1.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2254) DUF4436 PF14494.1 ETO28133.1 - 0.036 13.3 0.1 0.042 13.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) DUF607 PF04678.8 ETO28133.1 - 0.05 13.5 0.4 0.061 13.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF607 Transcrip_act PF04949.8 ETO28133.1 - 0.054 13.1 1.3 0.077 12.6 0.9 1.3 1 0 0 1 1 1 0 Transcriptional activator TrbL PF04610.9 ETO28133.1 - 0.057 13.1 0.0 0.062 12.9 0.0 1.0 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein DUF3160 PF11369.3 ETO28133.1 - 0.059 11.6 0.1 0.064 11.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3160) Uds1 PF15456.1 ETO28133.1 - 0.11 12.4 2.3 0.16 11.9 1.6 1.1 1 0 0 1 1 1 0 Up-regulated During Septation V-SNARE PF05008.10 ETO28133.1 - 0.12 12.4 1.9 0.2 11.8 1.3 1.4 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus MtrG PF04210.8 ETO28133.1 - 0.13 11.8 1.9 0.26 10.9 1.1 1.6 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G IFT57 PF10498.4 ETO28133.1 - 0.17 10.5 2.6 0.18 10.4 1.8 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF2951 PF11166.3 ETO28133.1 - 0.17 11.7 2.7 0.22 11.3 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) DUF4094 PF13334.1 ETO28133.1 - 0.18 12.1 4.2 0.19 12.1 1.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DUF3135 PF11333.3 ETO28133.1 - 0.19 11.9 1.1 0.38 10.9 0.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3135) Use1 PF09753.4 ETO28133.1 - 0.24 10.8 3.7 0.41 10.0 2.5 1.4 1 1 0 1 1 1 0 Membrane fusion protein Use1 Seryl_tRNA_N PF02403.17 ETO28133.1 - 0.31 11.0 3.7 0.5 10.3 2.6 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF2721 PF11026.3 ETO28133.1 - 0.77 9.4 6.5 1.8 8.1 1.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) DUF1003 PF06210.6 ETO28133.1 - 3.9 7.4 8.2 2.6 7.9 3.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) DUF4446 PF14584.1 ETO28133.1 - 8.5 6.1 11.3 1.5 8.6 1.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) V-SNARE PF05008.10 ETO28134.1 - 0.0056 16.8 4.1 0.011 15.9 2.9 1.5 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus Cauli_AT PF03233.8 ETO28134.1 - 0.013 15.2 1.5 0.021 14.5 0.9 1.5 1 1 1 2 2 2 0 Aphid transmission protein Laminin_I PF06008.9 ETO28134.1 - 0.038 13.2 3.5 0.55 9.5 0.1 2.1 1 1 1 2 2 2 0 Laminin Domain I DUF2730 PF10805.3 ETO28134.1 - 0.061 13.0 1.6 0.16 11.7 0.2 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF2730) Tropomyosin_1 PF12718.2 ETO28134.1 - 0.088 12.6 7.4 0.027 14.3 2.4 1.8 1 1 1 2 2 2 0 Tropomyosin like DUF837 PF05769.6 ETO28134.1 - 0.23 10.9 4.5 0.49 9.8 3.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF837) HemX PF04375.9 ETO28134.1 - 0.32 9.5 4.4 0.39 9.2 3.0 1.2 1 1 0 1 1 1 0 HemX Spectrin PF00435.16 ETO28134.1 - 0.37 11.1 7.8 4.3 7.6 0.7 2.5 1 1 0 2 2 2 0 Spectrin repeat APG6 PF04111.7 ETO28134.1 - 0.49 9.4 5.6 0.57 9.1 3.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4315 PF14193.1 ETO28134.1 - 1.3 8.9 6.2 5.5 6.9 0.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4315) Sec2p PF06428.6 ETO28134.1 - 1.7 8.5 5.2 5.1 6.9 3.6 1.8 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p Phlebovirus_NSM PF07246.6 ETO28134.1 - 1.8 7.6 4.7 2.2 7.3 3.3 1.0 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Cytochrom_B562 PF07361.6 ETO28134.1 - 2 8.8 5.0 21 5.6 0.6 2.4 1 1 1 2 2 2 0 Cytochrome b562 Med11 PF10280.4 ETO28134.1 - 2 8.4 6.1 0.53 10.3 1.8 1.8 2 1 0 2 2 2 0 Mediator complex protein YlqD PF11068.3 ETO28134.1 - 2.5 8.1 10.3 12 5.9 1.5 2.3 1 1 1 2 2 2 0 YlqD protein DUF4404 PF14357.1 ETO28134.1 - 3.8 7.9 6.0 5.4 7.5 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) IncA PF04156.9 ETO28134.1 - 8.1 5.9 9.2 48 3.4 6.4 1.8 1 1 0 1 1 1 0 IncA protein DUF3813 PF12758.2 ETO28134.1 - 9.4 6.4 9.2 13 6.0 1.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3813) SnoaL_2 PF12680.2 ETO28135.1 - 4.8e-05 23.7 0.0 0.0001 22.6 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like domain Selenoprotein_S PF06936.6 ETO28135.1 - 0.0023 17.5 7.8 0.0086 15.6 5.5 1.8 2 0 0 2 2 2 1 Selenoprotein S (SelS) SnoaL PF07366.7 ETO28135.1 - 0.022 14.3 0.0 0.06 12.9 0.0 1.7 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase DUF740 PF05340.7 ETO28135.1 - 0.032 12.6 5.8 0.043 12.1 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF740) SieB PF14163.1 ETO28135.1 - 0.099 12.2 3.4 2.9 7.4 0.9 2.3 2 0 0 2 2 2 0 Superinfection exclusion protein B Fumble PF03630.9 ETO28135.1 - 4.8 5.9 7.8 65 2.2 5.4 2.1 1 1 0 1 1 1 0 Fumble DUF616 PF04765.8 ETO28136.1 - 0.051 12.7 0.2 0.083 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF616) CRAL_TRIO PF00650.15 ETO28137.1 - 8.7e-12 44.8 0.2 1.1e-11 44.5 0.1 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain ATG11 PF10377.4 ETO28138.1 - 0.074 12.9 1.8 0.18 11.6 1.2 1.8 1 1 0 1 1 1 0 Autophagy-related protein 11 DUF4286 PF14114.1 ETO28138.1 - 0.13 12.4 1.2 0.19 12.0 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4286) VPS9 PF02204.13 ETO28139.1 - 1.4e-06 28.2 2.4 1.2e-05 25.3 0.8 2.6 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain MFS_Mycoplasma PF07672.8 ETO28139.1 - 0.0034 16.6 4.3 0.029 13.5 0.6 2.5 2 0 0 2 2 2 1 Mycoplasma MFS transporter YajC PF02699.10 ETO28139.1 - 0.012 15.2 0.6 0.012 15.2 0.4 2.2 2 0 0 2 2 2 0 Preprotein translocase subunit Ammonium_transp PF00909.16 ETO28139.1 - 0.019 13.4 0.1 0.037 12.5 0.0 1.4 1 0 0 1 1 1 0 Ammonium Transporter Family DUF3816 PF12822.2 ETO28139.1 - 0.08 12.8 0.0 0.08 12.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3816) DUF2242 PF10001.4 ETO28139.1 - 2.7 7.8 9.6 2.7 7.9 1.1 2.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2242) Herpes_capsid PF06112.6 ETO28139.1 - 4.2 7.3 26.8 0.6 10.1 5.2 2.4 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein DEP PF00610.16 ETO28140.1 - 3.5e-07 29.8 0.0 6.3e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Inhibitor_I71 PF12628.2 ETO28142.1 - 0.012 15.3 0.1 0.012 15.3 0.1 2.1 1 1 1 2 2 2 0 Falstatin, cysteine peptidase inhibitor Inos-1-P_synth PF01658.12 ETO28142.1 - 1.1 9.0 9.5 0.99 9.2 5.8 1.5 1 1 0 1 1 1 0 Myo-inositol-1-phosphate synthase Cwf_Cwc_15 PF04889.7 ETO28143.1 - 0.00012 21.9 9.5 0.00018 21.2 6.6 1.4 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 ETO28143.1 - 0.17 9.7 10.5 0.22 9.4 7.3 1.2 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.6 ETO28143.1 - 0.24 9.2 4.1 0.31 8.8 2.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.9 ETO28143.1 - 0.49 8.3 9.4 0.72 7.8 6.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Ebola_NP PF05505.7 ETO28143.1 - 0.55 8.2 13.2 0.63 8.0 9.2 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein TFIIF_alpha PF05793.7 ETO28143.1 - 4 5.7 20.2 0.0088 14.4 7.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3353 PF11833.3 ETO28144.1 - 0.018 14.5 1.7 0.02 14.3 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) Pex16 PF08610.5 ETO28144.1 - 0.12 11.3 4.6 0.13 11.2 3.2 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF3643 PF12356.3 ETO28144.1 - 0.18 11.1 0.8 0.2 10.9 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3643) DUF3987 PF13148.1 ETO28144.1 - 0.48 8.9 5.7 0.53 8.7 4.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) YqfQ PF14181.1 ETO28144.1 - 0.56 10.2 10.1 0.61 10.1 7.0 1.1 1 0 0 1 1 1 0 YqfQ-like protein Agouti PF05039.7 ETO28144.1 - 2.1 8.7 7.4 2.2 8.6 4.7 1.3 1 1 0 1 1 1 0 Agouti protein Sec62 PF03839.11 ETO28144.1 - 3.7 6.8 11.5 3.9 6.8 8.0 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 PAS_7 PF12860.2 ETO28145.1 - 0.0092 15.9 0.2 0.02 14.8 0.0 1.7 2 0 0 2 2 2 1 PAS fold Pox_P35 PF03213.9 ETO28145.1 - 0.016 14.2 1.7 0.024 13.6 1.2 1.2 1 0 0 1 1 1 0 Poxvirus P35 protein IncA PF04156.9 ETO28147.1 - 0.0046 16.5 0.9 0.0046 16.5 0.6 1.1 1 0 0 1 1 1 1 IncA protein MscS_porin PF12795.2 ETO28147.1 - 0.028 13.7 1.3 0.027 13.7 0.9 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF3584 PF12128.3 ETO28147.1 - 0.051 10.9 0.4 0.051 10.9 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) BRE1 PF08647.6 ETO28147.1 - 0.082 12.8 0.7 0.093 12.7 0.5 1.2 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Ribosomal_L29 PF00831.18 ETO28147.1 - 0.57 9.9 5.2 0.95 9.1 3.6 1.4 1 1 0 1 1 1 0 Ribosomal L29 protein PDZ_assoc PF10600.4 ETO28148.1 - 0.021 15.1 0.6 0.021 15.1 0.4 2.2 2 1 0 2 2 2 0 PDZ-associated domain of NMDA receptors Ras PF00071.17 ETO28149.1 - 1.1e-26 93.1 0.7 1.3e-25 89.6 0.5 2.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 ETO28149.1 - 0.0043 17.5 0.0 0.036 14.5 0.0 2.5 1 1 0 1 1 1 1 Miro-like protein MgtE_N PF03448.12 ETO28149.1 - 0.12 12.6 0.9 0.31 11.3 0.5 1.8 2 0 0 2 2 2 0 MgtE intracellular N domain Myf5 PF12232.3 ETO28150.1 - 9.1 6.9 9.8 1.4 9.6 2.0 2.3 2 0 0 2 2 2 0 Myogenic determination factor 5 DUF4044 PF13253.1 ETO28151.1 - 0.71 9.0 5.8 1.9 7.7 4.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Menin PF05053.8 ETO28152.1 - 0.18 9.9 8.2 0.28 9.2 5.7 1.3 1 0 0 1 1 1 0 Menin Neur_chan_memb PF02932.11 ETO28152.1 - 2.7 7.8 11.6 1.2 8.9 3.1 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF912 PF06024.7 ETO28152.1 - 3.1 7.8 16.8 12 5.9 7.5 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FAM60A PF15396.1 ETO28152.1 - 3.3 7.4 12.2 1.7 8.3 0.4 2.2 2 0 0 2 2 2 0 Protein Family FAM60A DUF4638 PF15472.1 ETO28152.1 - 4.6 6.7 10.2 0.55 9.7 2.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) DUF1675 PF07897.6 ETO28152.1 - 9.3 6.0 16.3 1.4 8.7 6.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) USP8_dimer PF08969.6 ETO28153.1 - 0.087 12.7 0.5 0.22 11.5 0.1 1.8 2 0 0 2 2 2 0 USP8 dimerisation domain Beta-TrCP_D PF12125.3 ETO28154.1 - 0.0087 15.6 1.1 0.063 12.8 0.1 2.6 2 0 0 2 2 2 1 D domain of beta-TrCP TPR_2 PF07719.12 ETO28155.1 - 0.011 15.6 2.6 3.2 7.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 ETO28155.1 - 0.051 13.2 0.5 0.25 11.0 0.0 2.4 2 0 0 2 2 2 0 TPR repeat UBA_3 PF09288.5 ETO28155.1 - 0.057 13.0 0.0 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain TPR_8 PF13181.1 ETO28155.1 - 0.061 13.1 0.9 2.3 8.2 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETO28155.1 - 0.1 12.5 0.9 6.2 6.8 0.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat Mpp10 PF04006.7 ETO28156.1 - 0.062 11.6 9.2 0.081 11.2 6.4 1.2 1 0 0 1 1 1 0 Mpp10 protein SOBP PF15279.1 ETO28156.1 - 1.7 8.9 8.1 0.33 11.3 0.5 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein Clr5 PF14420.1 ETO28157.1 - 0.028 14.3 0.0 0.064 13.1 0.0 1.6 1 0 0 1 1 1 0 Clr5 domain Racemase_4 PF13615.1 ETO28158.1 - 9.9e-13 48.2 0.0 2.7e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Putative alanine racemase DUF1777 PF08648.7 ETO28159.1 - 0.0015 18.2 18.0 0.0015 18.2 12.5 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) RAP1 PF07218.6 ETO28159.1 - 0.15 10.1 4.1 0.21 9.6 2.9 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-HC5HC2H_2 PF13832.1 ETO28160.1 - 5.1e-10 39.3 6.5 1.3e-09 37.9 4.5 1.6 1 1 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 ETO28160.1 - 5e-09 36.1 6.2 4.3e-08 33.1 4.7 2.0 1 1 1 2 2 2 1 PHD-like zinc-binding domain PHD PF00628.24 ETO28160.1 - 0.35 10.6 8.7 1.7 8.3 4.6 2.2 2 0 0 2 2 2 0 PHD-finger Endothelin PF00322.12 ETO28161.1 - 0.082 12.1 4.0 1.1 8.5 0.2 2.8 2 0 0 2 2 2 0 Endothelin family Pol_alpha_B_N PF08418.5 ETO28161.1 - 1.6 8.1 8.7 3.9 6.9 6.0 1.7 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Lactamase_B_3 PF13483.1 ETO28162.1 - 0.27 10.9 3.0 0.38 10.4 2.1 1.3 1 1 0 1 1 1 0 Beta-lactamase superfamily domain ALMT PF11744.3 ETO28162.1 - 5.6 5.5 7.1 6.9 5.2 4.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Menin PF05053.8 ETO28162.1 - 8.2 4.4 9.4 8.9 4.3 6.5 1.1 1 0 0 1 1 1 0 Menin DEAD PF00270.24 ETO28163.1 - 7.4e-41 139.4 0.0 1e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 ETO28163.1 - 0.00056 19.7 0.0 0.0016 18.3 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit TrbI_Ftype PF09677.5 ETO28163.1 - 0.075 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) Helicase_C PF00271.26 ETO28164.1 - 9.7e-27 92.6 0.7 1.2e-26 92.3 0.5 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 ETO28164.1 - 0.035 12.4 0.0 0.035 12.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) Helicase_C_2 PF13307.1 ETO28164.1 - 0.04 13.8 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 Helicase C-terminal domain Phage_integrase PF00589.17 ETO28164.1 - 0.066 12.8 0.0 0.083 12.5 0.0 1.1 1 0 0 1 1 1 0 Phage integrase family Git3 PF11710.3 ETO28165.1 - 1e-06 28.5 10.1 1e-06 28.5 7.0 2.1 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7tm_2 PF00002.19 ETO28165.1 - 0.00013 21.1 3.4 0.00013 21.1 2.4 2.5 1 1 2 3 3 3 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 ETO28165.1 - 0.0013 17.7 16.6 0.2 10.4 11.5 2.6 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor MAGE PF01454.14 ETO28165.1 - 0.077 12.3 0.2 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 MAGE family Drf_GBD PF06371.8 ETO28166.1 - 0.0065 15.8 2.0 0.0065 15.8 1.4 3.0 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain C1_4 PF07975.7 ETO28167.1 - 0.24 11.4 2.4 0.67 9.9 0.4 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain LCM PF04072.9 ETO28169.1 - 1.4e-07 31.2 0.0 7.2e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 Leucine carboxyl methyltransferase PC4 PF02229.11 ETO28170.1 - 0.012 14.8 0.2 0.023 13.9 0.1 1.4 1 0 0 1 1 1 0 Transcriptional Coactivator p15 (PC4) DUF3654 PF12376.3 ETO28172.1 - 0.006 16.4 2.2 0.011 15.4 1.5 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3654) SecA_DEAD PF07517.9 ETO28172.1 - 0.071 12.3 0.3 2.1 7.5 0.0 2.1 1 1 1 2 2 2 0 SecA DEAD-like domain DUF4568 PF15132.1 ETO28173.1 - 0.0037 16.4 0.0 0.0052 16.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4568) EF-hand_6 PF13405.1 ETO28174.1 - 0.01 15.6 1.3 0.03 14.2 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain MFS_1 PF07690.11 ETO28175.1 - 9.4e-22 77.1 39.0 5.6e-15 54.9 11.4 2.9 2 2 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETO28175.1 - 2.1e-13 49.5 23.9 5.2e-08 31.6 3.0 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein Zip PF02535.17 ETO28175.1 - 8 5.3 22.5 2.2 7.1 7.8 3.5 2 1 0 2 2 2 0 ZIP Zinc transporter zf-C2H2_4 PF13894.1 ETO28178.1 - 2.2e-07 30.7 34.8 3.5e-05 23.8 1.2 3.9 4 1 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 ETO28178.1 - 5.6e-06 26.3 19.6 0.0011 18.9 1.1 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 ETO28178.1 - 2.3e-05 24.4 14.6 0.00015 21.8 0.8 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-met PF12874.2 ETO28178.1 - 0.00088 19.3 16.2 0.073 13.2 2.0 3.6 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 ETO28178.1 - 0.0012 18.6 18.2 0.19 11.6 2.7 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETO28178.1 - 0.0034 17.6 3.6 0.0034 17.6 2.5 5.1 6 0 0 6 6 6 3 Zinc-finger double domain Amelogenin PF02948.10 ETO28178.1 - 0.012 16.2 2.1 0.015 15.9 1.5 1.1 1 0 0 1 1 1 0 Amelogenin C1_1 PF00130.17 ETO28178.1 - 0.69 9.6 22.6 0.19 11.4 3.9 3.3 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_2 PF12756.2 ETO28178.1 - 0.83 9.8 20.9 2.8 8.1 2.0 3.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Pyr_redox_2 PF07992.9 ETO28179.1 - 6.5e-30 104.5 0.8 1e-29 103.8 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 ETO28179.1 - 1.9e-27 95.4 0.2 1.2e-26 92.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain DEP PF00610.16 ETO28179.1 - 2.9e-19 68.5 0.1 5.4e-19 67.7 0.1 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Pyr_redox PF00070.22 ETO28179.1 - 1.8e-05 25.0 1.5 0.0017 18.6 0.0 3.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF3801 PF12687.2 ETO28179.1 - 0.041 13.4 1.1 0.085 12.4 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) LCD1 PF09798.4 ETO28180.1 - 2.8 5.8 6.0 3.1 5.6 4.2 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein FAM60A PF15396.1 ETO28180.1 - 9.3 5.9 6.7 9.7 5.8 4.6 1.0 1 0 0 1 1 1 0 Protein Family FAM60A LRR_6 PF13516.1 ETO28181.1 - 1.8e-06 27.3 19.0 0.038 14.0 0.1 6.4 6 0 0 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.2 ETO28181.1 - 0.0015 18.1 1.9 0.0015 18.1 1.3 4.2 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETO28181.1 - 2.2 8.6 13.8 6.7 7.1 0.1 6.0 5 1 0 5 5 5 0 Leucine Rich Repeat PPR_3 PF13812.1 ETO28182.1 - 2.9e-07 30.2 12.1 4.1 7.9 0.0 8.9 10 0 0 10 10 10 2 Pentatricopeptide repeat domain PPR PF01535.15 ETO28182.1 - 5e-07 29.2 15.4 1 9.4 0.0 8.9 11 0 0 11 11 11 3 PPR repeat DYW_deaminase PF14432.1 ETO28182.1 - 1.8e-05 24.6 3.1 6.7e-05 22.8 2.2 2.0 1 0 0 1 1 1 1 DYW family of nucleic acid deaminases PPR_2 PF13041.1 ETO28182.1 - 4.7e-05 23.2 15.8 0.23 11.4 0.0 7.3 7 1 1 8 8 8 2 PPR repeat family PPR_1 PF12854.2 ETO28182.1 - 0.0094 15.4 1.2 1.6 8.2 0.0 4.5 6 0 0 6 6 6 1 PPR repeat Mif2_N PF15624.1 ETO28182.1 - 0.03 14.9 0.5 0.049 14.2 0.4 1.3 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Prog_receptor PF02161.10 ETO28183.1 - 0.091 11.5 0.8 0.15 10.9 0.5 1.2 1 0 0 1 1 1 0 Progesterone receptor PPO1_KFDV PF12143.3 ETO28183.1 - 0.2 11.5 4.6 0.21 11.4 1.2 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF_B2219) Asp-B-Hydro_N PF05279.6 ETO28183.1 - 0.43 10.3 10.7 0.78 9.5 7.4 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region zf-RING_4 PF14570.1 ETO28184.1 - 0.039 13.5 1.5 0.039 13.5 1.1 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Mu-like_Com PF10122.4 ETO28184.1 - 0.23 10.5 3.2 0.48 9.5 2.2 1.4 1 0 0 1 1 1 0 Mu-like prophage protein Com zf-C3HC4_4 PF15227.1 ETO28184.1 - 0.34 10.8 5.8 0.32 10.9 2.6 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FYVE PF01363.16 ETO28184.1 - 0.53 10.2 4.9 1.8 8.4 0.7 2.3 2 0 0 2 2 2 0 FYVE zinc finger MBOAT PF03062.14 ETO28186.1 - 6.8e-23 81.2 30.4 6.3e-21 74.8 21.2 2.1 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 ETO28186.1 - 0.32 11.0 11.3 67 3.6 7.8 2.6 1 1 0 1 1 1 0 Membrane bound O-acyl transferase family MRI PF15325.1 ETO28186.1 - 1 10.3 4.8 0.85 10.6 2.3 1.6 2 0 0 2 2 2 0 Modulator of retrovirus infection TEX19 PF15553.1 ETO28187.1 - 0.16 11.8 3.3 0.055 13.3 0.3 1.7 2 0 0 2 2 2 0 Testis-expressed protein 19 Apis_Csd PF11671.3 ETO28187.1 - 0.37 10.5 10.4 0.087 12.6 4.8 1.6 2 0 0 2 2 2 0 Complementary sex determiner protein Mem_trans PF03547.13 ETO28187.1 - 0.54 8.4 3.1 1 7.6 2.1 1.5 1 1 0 1 1 1 0 Membrane transport protein Uso1_p115_head PF04869.9 ETO28188.1 - 0.002 16.9 0.2 0.0023 16.7 0.1 1.1 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region zf-RanBP PF00641.13 ETO28189.1 - 2.3e-06 26.5 3.2 5.6e-06 25.3 2.2 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.10 ETO28189.1 - 1.7 8.2 7.0 0.078 12.5 0.5 2.2 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger GlcNAc PF11397.3 ETO28190.1 - 2.2e-38 132.2 0.1 3.6e-38 131.5 0.1 1.3 1 1 0 1 1 1 1 Glycosyltransferase (GlcNAc) Glyco_trans_2_3 PF13632.1 ETO28190.1 - 0.0094 15.6 0.4 0.013 15.2 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Oxidored_q1_C PF01010.14 ETO28192.1 - 4.3 6.7 12.9 2.1 7.8 7.2 1.8 1 1 1 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus DUF3357 PF11837.3 ETO28194.1 - 0.014 15.2 0.9 0.047 13.5 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) DUF912 PF06024.7 ETO28194.1 - 0.092 12.8 0.8 0.48 10.4 0.0 2.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TPT PF03151.11 ETO28194.1 - 0.096 12.3 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Triose-phosphate Transporter family UCH PF00443.24 ETO28195.1 - 3.3e-44 151.0 5.8 3.3e-44 151.0 4.0 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO28195.1 - 6.9e-28 97.9 4.8 6.9e-28 97.9 3.3 2.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase TPR_11 PF13414.1 ETO28196.1 - 1.8e-21 75.5 29.8 5.3e-08 32.3 3.5 5.6 1 1 4 5 5 5 5 TPR repeat TPR_17 PF13431.1 ETO28196.1 - 2.2e-12 46.1 22.0 4.3e-05 23.3 0.8 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO28196.1 - 1e-09 37.5 28.3 0.008 16.0 0.1 7.5 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO28196.1 - 2.7e-08 33.0 20.0 0.021 14.5 0.4 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO28196.1 - 1e-07 31.9 10.1 0.56 10.9 0.4 6.2 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO28196.1 - 7.4e-06 25.3 34.7 0.0042 16.6 0.2 7.8 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO28196.1 - 0.0001 22.8 17.5 0.013 16.2 2.5 4.7 2 2 4 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 ETO28196.1 - 0.00024 20.9 27.3 0.01 15.7 5.8 4.5 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO28196.1 - 0.00031 21.0 17.5 0.64 10.3 1.7 5.8 3 1 3 6 6 6 2 Tetratricopeptide repeat Ribosomal_S4 PF00163.14 ETO28196.1 - 0.028 14.7 0.6 0.35 11.2 0.1 2.7 1 1 1 2 2 2 0 Ribosomal protein S4/S9 N-terminal domain TPR_9 PF13371.1 ETO28196.1 - 0.61 9.9 4.6 1.3 8.8 0.1 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETO28196.1 - 1 9.3 9.1 12 6.0 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO28196.1 - 4.5 7.2 17.2 6.3 6.7 0.1 5.6 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat La PF05383.12 ETO28197.1 - 4e-14 52.1 0.0 8e-14 51.1 0.0 1.5 1 0 0 1 1 1 1 La domain EF-hand_7 PF13499.1 ETO28198.1 - 0.014 15.5 0.1 0.19 11.8 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.1 ETO28198.1 - 0.02 14.7 0.0 0.085 12.7 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain DUF2439 PF10382.4 ETO28199.1 - 3.2e-05 24.0 0.5 0.00011 22.3 0.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) PDEase_I PF00233.14 ETO28200.1 - 1.3e-55 188.7 0.0 6.5e-54 183.1 0.0 2.6 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 ETO28200.1 - 0.013 15.5 0.0 0.036 14.0 0.0 1.8 1 0 0 1 1 1 0 HD domain FMN_dh PF01070.13 ETO28200.1 - 0.1 11.4 0.9 0.18 10.6 0.6 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase A2M_comp PF07678.9 ETO28201.1 - 0.038 13.2 2.4 0.018 14.3 0.4 1.6 2 0 0 2 2 2 0 A-macroglobulin complement component Sigma70_ner PF04546.8 ETO28202.1 - 0.25 10.9 3.8 0.23 11.0 1.4 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region CobT PF06213.7 ETO28202.1 - 1.7 7.6 9.3 2.5 7.1 6.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CENP-B_dimeris PF09026.5 ETO28202.1 - 1.8 8.8 8.6 3.7 7.8 6.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Mating_C PF12737.2 ETO28204.1 - 0.002 17.0 3.0 0.0029 16.5 2.1 1.1 1 0 0 1 1 1 1 C-terminal domain of homeodomain 1 AgrB PF04647.10 ETO28204.1 - 0.091 11.8 3.4 0.13 11.3 2.4 1.2 1 0 0 1 1 1 0 Accessory gene regulator B NESP55 PF06390.7 ETO28205.1 - 0.001 18.5 1.1 0.0016 17.8 0.8 1.4 1 0 0 1 1 1 1 Neuroendocrine-specific golgi protein P55 (NESP55) Bactofilin PF04519.8 ETO28205.1 - 0.19 11.7 4.1 0.29 11.1 2.4 1.7 2 0 0 2 2 2 0 Polymer-forming cytoskeletal Glyco_hydro_2 PF00703.16 ETO28205.1 - 0.22 12.0 7.2 0.49 10.8 4.9 1.7 1 1 0 1 1 1 0 Glycosyl hydrolases family 2 DUF1943 PF09172.6 ETO28205.1 - 0.38 9.5 4.3 0.21 10.4 1.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) Secretin PF00263.16 ETO28205.1 - 0.51 9.7 4.2 0.87 8.9 2.9 1.5 1 1 0 1 1 1 0 Bacterial type II and III secretion system protein DUF3394 PF11874.3 ETO28205.1 - 0.65 9.5 3.6 0.76 9.2 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) BMF PF15185.1 ETO28205.1 - 0.73 9.0 5.6 1.1 8.4 3.9 1.4 1 1 0 1 1 1 0 Bcl-2-modifying factor, apoptosis Nucleoplasmin PF03066.10 ETO28205.1 - 0.93 8.9 7.3 1.5 8.3 5.1 1.4 1 1 0 1 1 1 0 Nucleoplasmin DUF775 PF05603.7 ETO28205.1 - 3.4 7.1 5.9 4.5 6.7 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) RusA PF05866.6 ETO28205.1 - 4.8 7.6 6.4 2.9 8.2 1.9 2.1 1 1 1 2 2 2 0 Endodeoxyribonuclease RusA Kinesin PF00225.18 ETO28206.1 - 1.3e-51 175.3 0.0 1.3e-51 175.3 0.0 2.3 3 0 0 3 3 3 1 Kinesin motor domain CENP-F_leu_zip PF10473.4 ETO28206.1 - 1 9.2 33.9 0.3 10.9 8.3 3.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.7 ETO28206.1 - 2.6 7.8 17.2 0.81 9.4 0.5 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DNA_pol_A_exo1 PF01612.15 ETO28207.1 - 0.028 13.9 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 3'-5' exonuclease DNA_pol_A_exo1 PF01612.15 ETO28208.1 - 3e-13 49.6 0.0 8.8e-13 48.1 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease Cid2 PF09774.4 ETO28208.1 - 0.01 15.9 1.3 0.01 15.9 0.9 2.2 2 1 1 3 3 3 0 Caffeine-induced death protein 2 RAB3GAP2_N PF14655.1 ETO28208.1 - 3.3 6.6 8.5 0.1 11.6 1.0 1.8 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Sporozoite_P67 PF05642.6 ETO28208.1 - 9.8 3.8 16.0 0.037 11.9 4.3 1.8 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DEP PF00610.16 ETO28209.1 - 6.1e-14 51.5 0.0 1.7e-13 50.0 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DSPc PF00782.15 ETO28209.1 - 5.2e-05 22.8 2.0 0.00013 21.5 0.0 2.5 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 ETO28209.1 - 0.0004 20.4 0.1 0.0019 18.2 0.1 2.1 1 1 0 1 1 1 1 Inositol hexakisphosphate TMEM71 PF15121.1 ETO28209.1 - 0.018 14.7 0.4 0.068 12.9 0.0 2.1 2 0 0 2 2 2 0 TMEM71 protein family Y_phosphatase3 PF13350.1 ETO28209.1 - 0.052 13.7 0.7 0.052 13.7 0.5 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family DUF965 PF06135.7 ETO28209.1 - 0.11 12.5 0.4 0.28 11.2 0.3 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF965) VIT1 PF01988.14 ETO28210.1 - 7.2e-50 169.4 0.2 7.2e-50 169.4 0.1 1.8 2 0 0 2 2 2 1 VIT family DUF3784 PF12650.2 ETO28210.1 - 0.035 14.0 0.4 0.092 12.6 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF3216 PF11505.3 ETO28210.1 - 0.057 13.2 0.4 0.17 11.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3216) tRNA-synt_2b PF00587.20 ETO28211.1 - 1.5e-33 115.8 1.2 8.7e-16 57.9 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 ETO28211.1 - 6.6e-20 70.8 0.1 1.7e-13 50.3 0.0 2.2 2 0 0 2 2 2 2 Anticodon binding domain YvrJ PF12841.2 ETO28212.1 - 0.5 9.6 4.8 4.9 6.5 0.0 2.8 2 1 0 2 2 2 0 YvrJ protein family G-alpha PF00503.15 ETO28213.1 - 7.4e-12 44.6 2.0 1.9e-11 43.3 1.4 1.7 1 1 0 1 1 1 1 G-protein alpha subunit ABC_tran PF00005.22 ETO28213.1 - 0.0015 18.8 0.0 0.0031 17.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter Rad17 PF03215.10 ETO28213.1 - 0.0025 16.5 0.0 0.0033 16.1 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 ETO28213.1 - 0.0045 16.7 0.3 0.0093 15.6 0.0 1.7 2 0 0 2 2 2 1 Archaeal ATPase RNA_helicase PF00910.17 ETO28213.1 - 0.006 16.7 0.0 0.019 15.1 0.0 1.9 1 0 0 1 1 1 1 RNA helicase NB-ARC PF00931.17 ETO28213.1 - 0.0085 14.9 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain DUF258 PF03193.11 ETO28213.1 - 0.016 14.3 0.6 0.036 13.2 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 ETO28213.1 - 0.024 14.6 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 ETO28213.1 - 0.03 14.2 0.1 0.16 11.8 0.0 2.1 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.1 ETO28213.1 - 0.03 13.8 0.4 0.048 13.2 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 ETO28213.1 - 0.03 14.5 0.1 0.14 12.3 0.0 2.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 ETO28213.1 - 0.031 13.7 0.0 0.062 12.7 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 ETO28213.1 - 0.039 13.4 0.1 0.12 11.9 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.1 ETO28213.1 - 0.043 13.9 0.0 0.086 12.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 ETO28213.1 - 0.09 12.6 0.0 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 ETO28213.1 - 0.098 11.8 0.5 0.18 10.9 0.0 1.7 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 ETO28213.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF755 PF05501.6 ETO28213.1 - 0.38 10.8 9.7 0.65 10.0 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Apyrase PF06079.6 ETO28214.1 - 1.3e-61 208.3 6.5 8.4e-46 156.4 0.8 5.1 3 1 1 4 4 4 3 Apyrase NnrU PF07298.6 ETO28215.1 - 1.4 8.2 6.7 7.9 5.8 0.6 2.6 2 1 0 2 2 2 0 NnrU protein SOBP PF15279.1 ETO28216.1 - 4.5 7.5 20.5 6.2 7.1 14.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Glycohydro_20b2 PF14845.1 ETO28217.1 - 3.4 8.3 8.0 37 4.9 5.6 2.3 1 1 0 1 1 1 0 beta-acetyl hexosaminidase like CRAL_TRIO_2 PF13716.1 ETO28218.1 - 0.0084 16.0 0.6 0.01 15.7 0.4 1.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MS_channel PF00924.13 ETO28219.1 - 2.3e-09 36.9 4.1 2.3e-09 36.9 2.9 1.8 2 0 0 2 2 2 1 Mechanosensitive ion channel Pyridox_oxidase PF01243.15 ETO28220.1 - 8.7e-07 28.8 0.0 2.7e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNPOx_C PF10590.4 ETO28220.1 - 8.4e-06 25.1 2.0 1.6e-05 24.3 1.4 1.4 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.2 ETO28220.1 - 4.5e-05 23.6 0.0 0.00012 22.3 0.0 1.7 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_oxidase_2 PF13883.1 ETO28220.1 - 0.0047 16.7 1.4 0.0064 16.2 0.0 1.9 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase HEAT_2 PF13646.1 ETO28221.1 - 7.7e-09 35.7 0.0 0.0028 17.9 0.0 3.2 2 1 0 2 2 2 2 HEAT repeats HEAT PF02985.17 ETO28221.1 - 3e-05 23.7 7.9 0.049 13.7 0.0 4.3 4 0 0 4 4 4 2 HEAT repeat TFCD_C PF12612.3 ETO28221.1 - 0.062 12.7 0.1 0.062 12.7 0.1 2.7 3 1 0 3 3 3 0 Tubulin folding cofactor D C terminal HEAT_EZ PF13513.1 ETO28221.1 - 0.07 13.6 0.2 1.3 9.5 0.0 2.9 2 1 1 3 3 3 0 HEAT-like repeat Calreticulin PF00262.13 ETO28222.1 - 9.2e-102 340.4 23.1 1.3e-60 204.9 0.1 3.8 4 0 0 4 4 4 2 Calreticulin family DUF3850 PF12961.2 ETO28222.1 - 0.0047 16.8 0.4 0.66 9.9 0.0 3.1 4 0 0 4 4 4 1 Domain of Unknown Function with PDB structure (DUF3850) DUF3169 PF11368.3 ETO28222.1 - 0.99 8.5 4.1 24 4.0 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) Cation_efflux PF01545.16 ETO28225.1 - 1.1e-05 24.6 3.2 1.6e-05 24.1 2.2 1.3 1 0 0 1 1 1 1 Cation efflux family DUF4080 PF13311.1 ETO28225.1 - 0.11 12.5 0.2 0.44 10.5 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4080) Cation_efflux PF01545.16 ETO28226.1 - 2.9e-21 75.8 4.9 3.3e-21 75.6 3.4 1.0 1 0 0 1 1 1 1 Cation efflux family DUF4658 PF15555.1 ETO28226.1 - 0.031 14.1 0.2 0.045 13.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) RasGEF PF00617.14 ETO28227.1 - 1.5e-17 63.9 0.5 6.2e-08 32.5 0.0 2.9 1 1 1 2 2 2 2 RasGEF domain Pkinase PF00069.20 ETO28229.1 - 1.8e-31 109.2 0.0 2.1e-31 109.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO28229.1 - 3.6e-12 45.9 0.0 4e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO28229.1 - 0.013 14.4 0.9 0.19 10.6 0.6 2.1 1 1 0 1 1 1 0 Kinase-like APH PF01636.18 ETO28229.1 - 0.057 13.1 0.0 0.079 12.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 ETO28229.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.27 ETO28230.1 - 2e-45 151.0 9.7 7.6e-11 41.4 0.6 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO28230.1 - 0.00023 19.4 13.4 0.15 10.1 0.0 4.1 2 1 2 4 4 4 3 Nucleoporin Nup120/160 HARP PF07443.8 ETO28230.1 - 0.12 11.7 1.4 1.7 8.0 0.0 3.1 3 0 0 3 3 3 0 HepA-related protein (HARP) Menin PF05053.8 ETO28230.1 - 3.7 5.6 17.1 5.4 5.0 11.9 1.1 1 0 0 1 1 1 0 Menin Exonuc_VII_L PF02601.10 ETO28230.1 - 7.1 5.7 27.7 10 5.2 19.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Dynamitin PF04912.9 ETO28231.1 - 2e-10 40.0 1.8 2e-10 40.0 1.3 1.6 1 1 0 1 1 1 1 Dynamitin Dict-STAT-coil PF09267.5 ETO28231.1 - 0.012 15.7 1.1 0.012 15.7 0.8 1.6 2 0 0 2 2 2 0 Dictyostelium STAT, coiled coil Syntaxin PF00804.20 ETO28231.1 - 0.031 14.4 1.5 1.6 8.9 0.3 2.2 2 0 0 2 2 2 0 Syntaxin AATF-Che1 PF13339.1 ETO28231.1 - 0.31 11.1 2.9 0.15 12.2 0.3 1.6 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Thymosin PF01290.15 ETO28232.1 - 0.011 15.2 0.2 0.03 13.8 0.2 1.7 1 0 0 1 1 1 0 Thymosin beta-4 family Glyco_transf_7N PF13733.1 ETO28234.1 - 0.098 12.0 0.8 0.14 11.5 0.6 1.3 1 1 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 DUF3886 PF13025.1 ETO28234.1 - 0.48 10.4 5.5 0.42 10.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) Pneumovirus_M2 PF06436.6 ETO28234.1 - 0.49 9.6 7.6 0.55 9.4 5.3 1.0 1 0 0 1 1 1 0 Pneumovirus matrix protein 2 (M2) DUF719 PF05334.8 ETO28237.1 - 0.00062 19.8 4.9 0.00062 19.8 3.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF719) DUF1664 PF07889.7 ETO28237.1 - 0.35 10.6 10.0 0.42 10.4 4.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF3728 PF12528.3 ETO28237.1 - 3.3 8.1 7.3 0.34 11.3 0.6 2.5 3 1 0 3 3 3 0 Prepilin peptidase dependent protein C (DUF3728) bZIP_1 PF00170.16 ETO28238.1 - 0.00086 19.2 4.3 0.0023 17.8 3.0 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 ETO28238.1 - 8.4 6.3 14.0 0.13 12.0 4.2 2.2 2 0 0 2 2 2 0 Basic region leucine zipper DUF3439 PF11921.3 ETO28239.1 - 0.0088 15.7 7.0 0.021 14.5 4.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Apis_Csd PF11671.3 ETO28240.1 - 0.19 11.5 5.6 0.38 10.5 3.9 1.6 1 0 0 1 1 1 0 Complementary sex determiner protein Lipase_GDSL PF00657.17 ETO28241.1 - 3.5e-06 27.0 0.0 4.1e-06 26.7 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 ETO28241.1 - 8.6e-06 26.0 0.1 1.4e-05 25.2 0.0 1.4 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family RTC PF01137.16 ETO28242.1 - 6.6e-54 182.1 0.1 7.5e-48 162.2 0.1 2.0 2 0 0 2 2 2 2 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 ETO28242.1 - 7.9e-17 61.1 0.0 1.4e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain MutL_C PF08676.6 ETO28243.1 - 3.9e-12 45.9 3.0 2.8e-08 33.4 0.7 3.4 2 1 0 2 2 2 2 MutL C terminal dimerisation domain Glyco_hydro_38 PF01074.17 ETO28244.1 - 1.2e-13 51.0 3.7 2.7e-13 49.7 2.5 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Egg_lysin PF01303.12 ETO28244.1 - 0.073 13.0 0.1 0.098 12.6 0.1 1.1 1 0 0 1 1 1 0 Egg lysin (Sperm-lysin) B56 PF01603.15 ETO28245.1 - 8.4e-77 258.4 4.5 8.4e-77 258.4 3.1 2.3 2 0 0 2 2 2 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF3729 PF12526.3 ETO28246.1 - 2.9 9.2 6.2 5.3 8.4 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3729) SPX PF03105.14 ETO28247.1 - 0.0084 15.9 11.7 0.24 11.1 8.1 2.3 1 1 0 1 1 1 1 SPX domain DUF3246 PF11596.3 ETO28247.1 - 0.014 14.6 4.0 0.032 13.5 2.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Exo_endo_phos PF03372.18 ETO28248.1 - 5.6e-07 29.7 0.0 1.6e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MOR2-PAG1_C PF14225.1 ETO28249.1 - 9.3e-10 38.6 0.1 3e-09 37.0 0.0 1.7 2 0 0 2 2 2 1 Cell morphogenesis C-terminal Peptidase_C57 PF03290.8 ETO28249.1 - 0.04 12.4 0.0 0.12 10.8 0.0 1.7 2 0 0 2 2 2 0 Vaccinia virus I7 processing peptidase CbiA PF01656.18 ETO28250.1 - 3.7e-05 23.2 0.0 3.9e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain VirC1 PF07015.6 ETO28250.1 - 0.15 11.1 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 VirC1 protein DnaJ PF00226.26 ETO28251.1 - 4.8e-28 96.6 0.5 8.2e-28 95.9 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain Phage_rep_O PF04492.8 ETO28252.1 - 2.2 8.5 5.9 0.78 9.9 0.6 2.5 2 1 1 3 3 3 0 Bacteriophage replication protein O G-alpha PF00503.15 ETO28253.1 - 1.2e-18 66.9 10.3 3.6e-12 45.6 0.1 2.0 2 0 0 2 2 2 2 G-protein alpha subunit Arf PF00025.16 ETO28253.1 - 0.0071 15.6 2.2 0.81 8.9 0.4 2.3 1 1 0 2 2 2 2 ADP-ribosylation factor family DEP PF00610.16 ETO28253.1 - 0.055 13.2 0.1 12 5.7 0.0 2.3 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RNaseH_C PF09293.5 ETO28253.1 - 0.2 11.5 3.3 0.19 11.6 0.4 2.1 1 1 0 2 2 2 0 T4 RNase H, C terminal His_Phos_1 PF00300.17 ETO28254.1 - 2.9e-06 27.4 0.0 4.3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PHD PF00628.24 ETO28256.1 - 5.3e-09 35.6 7.5 5.3e-09 35.6 5.2 3.6 2 1 1 3 3 3 1 PHD-finger zf-RING_2 PF13639.1 ETO28256.1 - 2e-06 27.5 2.3 2e-06 27.5 1.6 3.7 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 ETO28256.1 - 4.1e-05 23.6 2.2 4.1e-05 23.6 1.5 3.2 2 1 0 2 2 2 1 RING-H2 zinc finger PHD_2 PF13831.1 ETO28256.1 - 0.0086 15.3 1.0 0.0086 15.3 0.7 2.9 3 0 0 3 3 3 1 PHD-finger zf-C3HC4_3 PF13920.1 ETO28256.1 - 0.023 14.3 0.8 0.023 14.3 0.6 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO28256.1 - 0.027 14.4 1.7 0.027 14.4 1.2 3.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 ETO28256.1 - 0.034 13.9 8.8 0.053 13.3 0.8 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Lin-8 PF03353.10 ETO28256.1 - 0.1 11.8 9.4 0.17 11.1 6.5 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist zf-CCHC_5 PF14787.1 ETO28256.1 - 0.63 9.5 10.5 0.17 11.4 0.2 3.6 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger zf-C2H2_6 PF13912.1 ETO28256.1 - 5.7 6.9 10.4 0.62 10.0 0.1 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger Rad51 PF08423.6 ETO28257.1 - 2e-05 23.6 0.0 2.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Rad51 KaiC PF06745.8 ETO28257.1 - 9.7e-05 21.5 0.0 0.00021 20.5 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_14 PF13173.1 ETO28257.1 - 1.2 9.0 4.9 0.41 10.5 0.1 2.5 2 2 0 2 2 2 0 AAA domain ADH_zinc_N PF00107.21 ETO28258.1 - 3.8e-23 81.4 0.1 9.1e-23 80.2 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Esterase PF00756.15 ETO28258.1 - 2.9e-22 79.3 0.0 6e-22 78.2 0.0 1.4 1 1 0 1 1 1 1 Putative esterase ADH_N PF08240.7 ETO28258.1 - 1.1e-19 70.2 0.3 2.6e-19 68.9 0.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 ETO28258.1 - 0.0047 17.8 0.0 0.015 16.2 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 ETO28258.1 - 0.078 12.1 0.1 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.16 ETO28258.1 - 0.12 12.1 0.4 0.32 10.8 0.3 1.7 1 0 0 1 1 1 0 ThiF family Abhydrolase_6 PF12697.2 ETO28258.1 - 0.17 11.7 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3272 PF11676.3 ETO28259.1 - 0.11 12.5 0.5 0.22 11.5 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3272) XPG_I PF00867.13 ETO28260.1 - 7.1e-18 64.4 0.0 1.3e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 ETO28260.1 - 7.7e-09 35.3 0.0 7.8e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 XPG domain containing Herpes_UL33 PF03581.8 ETO28260.1 - 0.03 14.2 0.9 4.4 7.2 0.0 2.1 1 1 1 2 2 2 0 Herpesvirus UL33-like protein BSP_II PF05432.6 ETO28262.1 - 0.00083 18.7 8.4 0.0011 18.3 5.8 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) CDC45 PF02724.9 ETO28262.1 - 0.0035 15.4 12.8 0.004 15.2 8.9 1.0 1 0 0 1 1 1 1 CDC45-like protein Sporozoite_P67 PF05642.6 ETO28262.1 - 0.011 13.5 14.9 0.013 13.3 10.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mpp10 PF04006.7 ETO28262.1 - 0.029 12.7 16.9 0.033 12.5 11.7 1.0 1 0 0 1 1 1 0 Mpp10 protein Raftlin PF15250.1 ETO28262.1 - 0.037 12.5 3.9 0.039 12.4 2.7 1.0 1 0 0 1 1 1 0 Raftlin SDA1 PF05285.7 ETO28262.1 - 0.058 12.6 15.7 0.073 12.3 10.9 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 ETO28262.1 - 0.077 10.9 23.3 0.098 10.5 16.1 1.0 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 ETO28262.1 - 0.13 10.7 19.3 0.15 10.5 13.4 1.0 1 0 0 1 1 1 0 Daxx Family Suf PF05843.9 ETO28262.1 - 0.21 11.2 3.6 0.2 11.3 2.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Membralin PF09746.4 ETO28262.1 - 0.3 10.0 1.1 0.36 9.8 0.8 1.1 1 0 0 1 1 1 0 Tumour-associated protein TRAP_alpha PF03896.11 ETO28262.1 - 0.37 9.7 6.2 0.45 9.4 4.3 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF1510 PF07423.6 ETO28262.1 - 0.56 9.5 17.0 0.82 8.9 11.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Hid1 PF12722.2 ETO28262.1 - 0.71 7.4 9.8 0.75 7.3 6.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CobT PF06213.7 ETO28262.1 - 0.79 8.8 19.6 0.94 8.5 13.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.5 ETO28262.1 - 1 8.3 26.0 1.3 8.0 18.0 1.0 1 0 0 1 1 1 0 BUD22 SAPS PF04499.10 ETO28262.1 - 1.1 7.8 11.8 1.3 7.6 8.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NOA36 PF06524.7 ETO28262.1 - 1.2 8.3 11.1 1.5 7.9 7.7 1.3 1 0 0 1 1 1 0 NOA36 protein RCR PF12273.3 ETO28262.1 - 2 8.9 7.4 2.8 8.5 5.1 1.2 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Lin-8 PF03353.10 ETO28262.1 - 5.8 6.1 15.2 7.2 5.7 10.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist FAM60A PF15396.1 ETO28262.1 - 6.5 6.4 7.8 10 5.7 5.4 1.4 1 0 0 1 1 1 0 Protein Family FAM60A YfhD PF14151.1 ETO28265.1 - 1.5 8.9 8.5 1.4 9.1 0.9 2.9 1 1 0 2 2 2 0 YfhD-like protein eIF-3c_N PF05470.7 ETO28265.1 - 2.1 6.3 10.2 2.5 6.0 7.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF4614 PF15391.1 ETO28265.1 - 3.8 7.2 8.3 4.1 7.1 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) WD40 PF00400.27 ETO28266.1 - 3.2e-64 210.6 12.2 2.6e-12 46.1 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat Kelch_1 PF01344.20 ETO28266.1 - 2.2e-08 33.5 8.2 2e-05 24.0 1.7 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO28266.1 - 1.6e-06 28.0 7.8 0.015 15.4 0.0 4.3 3 1 1 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO28266.1 - 0.00064 19.4 2.9 0.72 9.6 0.2 4.4 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO28266.1 - 0.0032 17.1 1.6 2.1 8.2 0.3 4.0 3 0 0 3 3 3 1 Kelch motif PD40 PF07676.7 ETO28266.1 - 0.011 15.3 11.2 2.8 7.7 0.0 5.6 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 ETO28266.1 - 0.015 14.5 6.3 15 5.0 0.0 5.2 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Kelch_3 PF13415.1 ETO28266.1 - 0.026 14.7 0.2 0.24 11.6 0.0 2.7 2 0 0 2 2 2 0 Galactose oxidase, central domain PQQ_2 PF13360.1 ETO28266.1 - 0.037 13.4 0.0 15 4.9 0.0 2.4 1 1 0 2 2 2 0 PQQ-like domain Kelch_5 PF13854.1 ETO28266.1 - 1.9 8.5 7.9 2.3 8.2 0.9 3.3 4 0 0 4 4 4 0 Kelch motif Sulfatase PF00884.18 ETO28267.1 - 9.1e-55 186.0 1.4 9.1e-55 186.0 1.0 1.8 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 ETO28267.1 - 4.2e-07 29.6 1.4 1.2e-05 24.8 1.0 2.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 ETO28267.1 - 0.00018 21.7 0.2 0.00051 20.3 0.2 1.8 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF1501 PF07394.7 ETO28267.1 - 0.0051 15.7 0.0 0.0087 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) LUC7 PF03194.10 ETO28267.1 - 0.014 14.9 0.1 0.028 13.9 0.1 1.4 1 0 0 1 1 1 0 LUC7 N_terminus DDHD PF02862.12 ETO28268.1 - 2.3 7.9 18.8 6 6.6 13.0 1.8 1 0 0 1 1 1 0 DDHD domain Band_3_cyto PF07565.8 ETO28268.1 - 5.4 6.4 10.9 13 5.2 7.6 1.8 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Zip PF02535.17 ETO28268.1 - 9.1 5.1 8.8 18 4.2 6.1 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter WD40 PF00400.27 ETO28269.1 - 0.0005 19.8 3.8 0.01 15.6 0.0 3.9 4 1 0 4 4 4 1 WD domain, G-beta repeat DUF2947 PF11163.3 ETO28269.1 - 0.092 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) Circo_capsid PF02443.10 ETO28269.1 - 0.32 10.3 14.5 0.43 9.9 10.1 1.2 1 0 0 1 1 1 0 Circovirus capsid protein PEHE PF15275.1 ETO28269.1 - 0.55 10.6 6.0 0.44 10.9 3.0 1.7 2 0 0 2 2 2 0 PEHE domain PolyA_pol_RNAbd PF12627.2 ETO28270.1 - 1.3e-05 24.6 0.3 0.00011 21.6 0.0 2.5 3 0 0 3 3 3 1 Probable RNA and SrmB- binding site of polymerase A DUF2763 PF10961.3 ETO28271.1 - 0.042 14.2 1.1 0.042 14.2 0.8 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2763) BAF1_ABF1 PF04684.8 ETO28273.1 - 2.7 6.7 11.2 4.1 6.1 7.8 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor NACHT PF05729.7 ETO28274.1 - 3.5e-10 39.8 0.0 1.5e-09 37.7 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.1 ETO28274.1 - 4.5e-06 26.9 2.9 5.2e-05 23.5 0.1 3.8 4 0 0 4 4 4 1 AAA domain AAA_17 PF13207.1 ETO28274.1 - 2.4e-05 25.1 0.3 0.0024 18.7 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 ETO28274.1 - 6.7e-05 23.0 0.1 0.00064 19.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain NOB1_Zn_bind PF08772.6 ETO28274.1 - 0.00023 20.9 2.6 0.48 10.2 0.0 3.2 3 0 0 3 3 3 2 Nin one binding (NOB1) Zn-ribbon like RNA_helicase PF00910.17 ETO28274.1 - 0.0054 16.8 0.8 0.3 11.2 0.1 3.7 3 1 0 3 3 3 1 RNA helicase Zn_Tnp_IS1595 PF12760.2 ETO28274.1 - 0.044 13.6 2.6 5.5 6.8 0.1 2.7 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-H2C2_2 PF13465.1 ETO28274.1 - 0.058 13.7 10.3 2.1 8.7 1.0 3.1 2 0 0 2 2 2 0 Zinc-finger double domain ABC_tran PF00005.22 ETO28274.1 - 0.083 13.1 0.3 0.55 10.5 0.0 2.6 3 0 0 3 3 3 0 ABC transporter Ctf8 PF09696.5 ETO28274.1 - 0.098 12.4 6.2 1.3 8.7 0.0 3.4 4 0 0 4 4 3 0 Ctf8 Zn-ribbon_8 PF09723.5 ETO28274.1 - 0.17 11.8 4.0 10 6.1 0.2 2.8 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_4 PF13894.1 ETO28274.1 - 1 9.8 5.6 34 5.0 0.2 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 ETO28274.1 - 2.4 8.6 9.0 18 5.9 0.8 3.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type A2L_zn_ribbon PF08792.5 ETO28274.1 - 3 7.4 8.9 5.3 6.6 0.3 3.8 4 0 0 4 4 4 0 A2L zinc ribbon domain WD40 PF00400.27 ETO28275.1 - 3e-158 508.7 33.1 3.3e-13 48.9 0.2 16.2 16 0 0 16 16 16 16 WD domain, G-beta repeat DUF1258 PF06869.7 ETO28275.1 - 1.1e-06 27.9 2.0 0.41 9.6 0.0 5.5 4 4 0 5 5 5 2 Protein of unknown function (DUF1258) Mid2 PF04478.7 ETO28275.1 - 8.8e-06 25.2 16.1 1.7 8.0 0.0 8.9 5 5 5 10 10 10 2 Mid2 like cell wall stress sensor Gmad1 PF10647.4 ETO28275.1 - 2.4e-05 23.8 0.0 0.12 11.7 0.0 4.2 3 1 2 5 5 5 1 Lipoprotein LpqB beta-propeller domain Pentapeptide PF00805.17 ETO28275.1 - 6.7e-05 22.0 2.0 0.00016 20.8 1.4 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Cytochrom_D1 PF02239.11 ETO28275.1 - 0.00013 20.4 6.1 0.063 11.5 0.0 5.0 3 2 2 6 6 6 2 Cytochrome D1 heme domain PD40 PF07676.7 ETO28275.1 - 0.00052 19.6 21.3 4.4 7.0 0.1 9.4 10 0 0 10 10 10 2 WD40-like Beta Propeller Repeat Pentapeptide_4 PF13599.1 ETO28275.1 - 0.00053 19.7 0.9 0.002 17.8 0.6 2.0 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 ETO28275.1 - 0.0024 17.7 1.7 0.011 15.6 0.5 2.7 2 1 1 3 3 3 1 Pentapeptide repeats (9 copies) NYD-SP28_assoc PF14775.1 ETO28275.1 - 0.0042 16.7 9.0 80 3.0 0.0 8.9 12 0 0 12 12 12 0 Sperm tail C-terminal domain DUF1652 PF07865.6 ETO28275.1 - 0.0074 15.8 2.6 93 2.7 0.0 7.2 9 0 0 9 9 9 0 Protein of unknown function (DUF1652) PLD_C PF12357.3 ETO28275.1 - 0.062 12.8 0.5 2.2e+02 1.4 0.0 6.3 9 0 0 9 9 9 0 Phospholipase D C terminal RGS PF00615.14 ETO28276.1 - 1.9e-05 24.7 0.0 6.3e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 Regulator of G protein signaling domain Gly_transf_sug PF04488.10 ETO28277.1 - 3.1e-10 40.3 0.3 5.4e-10 39.5 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 ETO28277.1 - 0.00014 21.0 0.3 0.00022 20.5 0.2 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein DUF2762 PF10960.3 ETO28278.1 - 3.1 7.5 12.9 1.9 8.2 1.5 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF2762) MNSV_P7B PF06692.6 ETO28279.1 - 0.15 11.8 0.3 0.15 11.8 0.2 1.7 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein 7tm_1 PF00001.16 ETO28280.1 - 0.0045 16.1 7.4 0.0045 16.1 5.1 1.6 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Ctr PF04145.10 ETO28280.1 - 0.016 15.2 1.9 0.016 15.2 1.3 2.1 1 1 1 2 2 2 0 Ctr copper transporter family PDR_CDR PF06422.7 ETO28280.1 - 0.02 14.5 7.9 0.37 10.4 1.0 2.4 1 1 1 2 2 2 0 CDR ABC transporter DUF2149 PF09919.4 ETO28280.1 - 0.021 14.9 3.8 0.55 10.3 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) DUF4094 PF13334.1 ETO28280.1 - 0.027 14.8 2.5 0.027 14.8 1.7 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4094) N6_Mtase PF02384.11 ETO28280.1 - 0.037 13.1 8.3 0.0075 15.3 3.6 1.5 2 0 0 2 2 2 0 N-6 DNA Methylase ABC_membrane_2 PF06472.10 ETO28280.1 - 0.047 12.8 1.8 0.067 12.3 1.2 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 7TM_GPCR_Srh PF10318.4 ETO28280.1 - 0.074 11.8 2.8 0.095 11.4 1.9 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Srd PF10317.4 ETO28280.1 - 0.093 11.7 3.6 0.28 10.1 2.5 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd Viral_Beta_CD PF04530.7 ETO28280.1 - 0.11 12.6 5.7 2.2 8.4 0.1 2.6 1 1 2 3 3 3 0 Viral Beta C/D like family Zip PF02535.17 ETO28280.1 - 0.49 9.3 7.4 4.7 6.1 5.2 2.0 1 1 0 1 1 1 0 ZIP Zinc transporter CD20 PF04103.10 ETO28280.1 - 0.95 9.3 4.2 0.23 11.3 0.4 1.7 1 1 1 2 2 2 0 CD20-like family Conotoxin PF02950.12 ETO28280.1 - 1.1 10.0 18.1 1 10.2 3.4 2.9 1 1 2 3 3 3 0 Conotoxin Serinc PF03348.10 ETO28280.1 - 1.7 7.2 11.8 0.054 12.2 1.6 1.9 1 1 1 2 2 2 0 Serine incorporator (Serinc) Tmem26 PF09772.4 ETO28280.1 - 1.8 7.6 7.3 1.4 8.0 2.2 2.1 1 1 1 2 2 2 0 Transmembrane protein 26 Kei1 PF08552.6 ETO28280.1 - 2.6 7.6 5.9 43 3.6 4.0 2.1 1 1 1 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 PSK PF06404.7 ETO28280.1 - 3.5 8.4 8.9 3.1 8.6 0.3 3.0 3 0 0 3 3 3 0 Phytosulfokine precursor protein (PSK) Nucleoside_tran PF01733.13 ETO28280.1 - 8.1 5.5 9.1 1.6 7.8 3.7 1.6 1 1 1 2 2 2 0 Nucleoside transporter Beach PF02138.13 ETO28282.1 - 5.9e-103 344.0 4.5 7.3e-73 245.3 0.9 2.2 2 0 0 2 2 2 2 Beige/BEACH domain PH_BEACH PF14844.1 ETO28282.1 - 4.5e-13 48.9 0.5 1.4e-12 47.4 0.4 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF3753 PF12575.3 ETO28282.1 - 0.0045 16.7 1.7 0.15 11.8 2.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3753) ABC2_membrane_5 PF13346.1 ETO28282.1 - 0.027 13.7 4.4 0.057 12.6 3.1 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein 7TM-7TMR_HD PF07698.6 ETO28282.1 - 0.041 13.3 0.4 0.066 12.6 0.3 1.2 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase Cation_ATPase_C PF00689.16 ETO28282.1 - 0.055 12.9 0.1 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus Methyltransf_12 PF08242.7 ETO28282.1 - 0.47 10.9 3.7 1.3 9.5 0.3 2.5 2 0 0 2 2 2 0 Methyltransferase domain Arginase PF00491.16 ETO28283.1 - 8e-33 113.9 0.0 9.9e-33 113.6 0.0 1.0 1 0 0 1 1 1 1 Arginase family Arginase PF00491.16 ETO28284.1 - 3.6e-16 59.2 0.0 1e-15 57.7 0.0 1.8 1 1 0 1 1 1 1 Arginase family UPF0489 PF12640.2 ETO28284.1 - 0.006 16.8 2.1 0.0089 16.2 0.1 2.2 2 1 0 2 2 2 1 UPF0489 domain DUF1451 PF07295.6 ETO28284.1 - 0.028 14.1 1.4 0.18 11.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1451) LMF1 PF06762.9 ETO28285.1 - 1.9e-74 250.7 10.6 2.6e-74 250.3 7.4 1.2 1 0 0 1 1 1 1 Lipase maturation factor WD40 PF00400.27 ETO28286.1 - 1.1e-06 28.2 6.3 1.7e-05 24.4 0.8 3.6 3 1 0 3 3 3 2 WD domain, G-beta repeat HEAT_2 PF13646.1 ETO28287.1 - 1.7e-11 44.2 1.6 0.07 13.4 0.0 4.5 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.17 ETO28287.1 - 2.5e-09 36.4 0.9 0.11 12.6 0.0 4.5 3 0 0 3 3 3 3 HEAT repeat HEAT_EZ PF13513.1 ETO28287.1 - 2.9e-06 27.5 1.2 0.019 15.4 0.2 4.2 2 2 2 4 4 4 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 ETO28287.1 - 3.8e-06 27.1 4.4 0.019 15.3 0.0 4.7 2 1 2 4 4 4 2 Vacuolar 14 Fab1-binding region DUF3554 PF12074.3 ETO28287.1 - 4.7e-05 22.9 3.9 0.58 9.5 0.0 3.3 3 0 0 3 3 3 3 Domain of unknown function (DUF3554) TIP120 PF08623.5 ETO28287.1 - 7.4e-05 22.3 9.1 0.033 13.7 0.4 4.2 3 2 1 4 4 4 2 TATA-binding protein interacting (TIP20) UME PF08064.8 ETO28287.1 - 0.00016 21.5 4.0 0.15 12.0 0.4 3.3 2 0 0 2 2 2 2 UME (NUC010) domain DUF2435 PF10363.4 ETO28287.1 - 0.0002 21.2 4.2 0.72 9.7 0.0 4.6 4 1 1 5 5 5 2 Protein of unknown function (DUF2435) DUF1856 PF08983.5 ETO28287.1 - 0.098 12.7 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1856) Aa_trans PF01490.13 ETO28288.1 - 1.1e-43 149.2 13.5 1.5e-43 148.8 9.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein HCO3_cotransp PF00955.16 ETO28288.1 - 0.021 13.5 1.2 0.021 13.5 0.8 1.8 2 1 1 3 3 3 0 HCO3- transporter family O-antigen_lig PF13425.1 ETO28288.1 - 0.59 10.1 11.5 0.2 11.6 0.5 3.1 3 0 0 3 3 3 0 O-antigen ligase like membrane protein KbaA PF14089.1 ETO28288.1 - 5.4 6.5 8.4 12 5.3 0.5 3.0 3 1 0 3 3 3 0 KinB-signalling pathway activation in sporulation PAP_assoc PF03828.14 ETO28289.1 - 4.3e-09 36.1 0.5 1.9e-08 34.1 0.4 2.2 1 1 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 ETO28289.1 - 4.2e-05 23.8 0.0 0.00016 21.9 0.0 2.0 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF1923 PF09083.5 ETO28289.1 - 0.036 13.5 0.0 0.079 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1923) Pkinase PF00069.20 ETO28292.1 - 0.00063 18.9 0.0 0.00081 18.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain CTP_transf_2 PF01467.21 ETO28293.1 - 0.015 15.3 2.6 0.036 14.1 1.8 1.7 1 0 0 1 1 1 0 Cytidylyltransferase RRM_1 PF00076.17 ETO28294.1 - 0.0016 18.0 0.0 0.0031 17.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO28294.1 - 0.0025 17.7 0.0 0.0061 16.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ERCC4 PF02732.10 ETO28294.1 - 0.022 14.5 0.4 0.055 13.2 0.0 1.8 2 0 0 2 2 2 0 ERCC4 domain DUF912 PF06024.7 ETO28295.1 - 0.008 16.2 4.7 0.36 10.9 0.0 3.6 3 0 0 3 3 3 2 Nucleopolyhedrovirus protein of unknown function (DUF912) Viral_Beta_CD PF04530.7 ETO28295.1 - 0.39 10.8 6.3 3.4 7.8 0.1 3.6 3 0 0 3 3 3 0 Viral Beta C/D like family Trypsin_2 PF13365.1 ETO28296.1 - 1.7e-14 53.7 0.9 9.1e-14 51.4 0.1 2.3 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.21 ETO28296.1 - 1.6e-11 44.1 0.1 3.4e-10 39.8 0.0 2.3 1 1 0 1 1 1 1 Trypsin DUF563 PF04577.9 ETO28297.1 - 8e-08 32.4 1.1 1.8e-07 31.3 0.7 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Kinesin PF00225.18 ETO28301.1 - 2e-34 118.8 0.4 2e-34 118.8 0.3 1.7 2 1 0 2 2 2 1 Kinesin motor domain Syntaxin-18_N PF10496.4 ETO28301.1 - 0.0038 17.0 1.6 1.6 8.6 0.0 2.7 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus Ax_dynein_light PF10211.4 ETO28301.1 - 0.011 15.5 4.9 0.019 14.8 3.4 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain PsiB PF06290.6 ETO28301.1 - 0.013 14.9 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Plasmid SOS inhibition protein (PsiB) UPF0184 PF03670.8 ETO28301.1 - 0.014 15.5 1.8 7.9 6.7 0.0 2.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0184) DUF837 PF05769.6 ETO28301.1 - 0.026 14.0 8.7 0.012 15.1 4.3 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF837) HNH_5 PF14279.1 ETO28301.1 - 0.078 12.9 0.3 0.21 11.5 0.2 1.9 1 0 0 1 1 1 0 HNH endonuclease DUF520 PF04461.8 ETO28301.1 - 0.12 12.1 5.3 7.3 6.4 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF520) Nup54 PF13874.1 ETO28301.1 - 0.13 11.9 6.1 0.35 10.5 3.3 2.1 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Enkurin PF13864.1 ETO28301.1 - 0.25 11.5 10.2 0.08 13.1 4.8 1.8 2 0 0 2 2 2 0 Calmodulin-binding Cauli_AT PF03233.8 ETO28301.1 - 0.26 10.9 4.6 0.87 9.2 3.1 2.0 1 1 0 1 1 1 0 Aphid transmission protein A_thal_3526 PF09713.5 ETO28301.1 - 0.97 9.6 3.8 5 7.3 0.9 3.0 2 1 0 2 2 2 0 Plant protein 1589 of unknown function (A_thal_3526) Mto2_bdg PF12808.2 ETO28301.1 - 1.1 9.3 7.2 0.66 10.1 1.4 2.9 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region bZIP_2 PF07716.10 ETO28301.1 - 6.6 6.6 11.8 0.89 9.4 4.8 2.1 2 0 0 2 2 2 0 Basic region leucine zipper IncA PF04156.9 ETO28301.1 - 7.2 6.1 8.3 2 7.9 3.5 1.7 2 0 0 2 2 2 0 IncA protein FSH1 PF03959.8 ETO28302.1 - 0.27 10.6 4.6 4.9 6.5 0.4 2.3 2 0 0 2 2 2 0 Serine hydrolase (FSH1) TRAP_alpha PF03896.11 ETO28302.1 - 0.81 8.6 11.4 1.4 7.8 7.9 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2312 PF10073.4 ETO28303.1 - 3.3e-05 23.1 0.4 0.00022 20.5 0.0 2.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2312) DEAD PF00270.24 ETO28304.1 - 1.1e-20 73.8 0.2 3.2e-20 72.2 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETO28304.1 - 1.1e-15 57.1 1.3 1.2e-12 47.4 0.0 3.6 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RNA_pol_Rpb1_5 PF04998.12 ETO28304.1 - 1.2 8.3 10.6 0.74 9.0 2.5 2.5 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 5 Vfa1 PF08432.5 ETO28305.1 - 0.014 15.4 30.2 0.078 13.0 0.7 3.3 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 Sigma70_ner PF04546.8 ETO28305.1 - 0.45 10.1 19.9 0.8 9.2 5.5 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region NACHT PF05729.7 ETO28306.1 - 1.1e-08 34.9 0.0 1.6e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 ETO28306.1 - 1.1e-06 28.5 0.1 1.6e-06 28.0 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 ETO28306.1 - 0.00011 22.3 0.0 0.00018 21.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETO28306.1 - 0.00023 21.1 0.0 0.00039 20.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 ETO28306.1 - 0.00032 19.6 0.0 0.00044 19.2 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_10 PF12846.2 ETO28306.1 - 0.0028 17.1 0.0 0.0038 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain ORC2 PF04084.9 ETO28306.1 - 0.03 13.1 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 2 DUF258 PF03193.11 ETO28306.1 - 0.035 13.2 0.1 0.077 12.1 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Peptidase_M15 PF01427.12 ETO28306.1 - 0.06 12.9 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 D-ala-D-ala dipeptidase RmuC PF02646.11 ETO28307.1 - 0.011 14.6 1.6 0.013 14.3 1.1 1.1 1 0 0 1 1 1 0 RmuC family Sec20 PF03908.8 ETO28307.1 - 0.033 13.8 0.7 0.047 13.3 0.5 1.3 1 0 0 1 1 1 0 Sec20 WD40 PF00400.27 ETO28308.1 - 2.3e-75 246.0 14.2 5.6e-14 51.3 0.0 7.0 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO28308.1 - 5.1e-12 45.9 0.1 0.00011 21.9 0.0 3.3 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO28308.1 - 2.2e-10 39.3 6.0 0.0011 17.2 0.1 4.5 1 1 2 3 3 3 2 Nucleoporin Nup120/160 DUF1258 PF06869.7 ETO28308.1 - 4.6e-08 32.4 1.4 0.0072 15.4 0.1 3.4 2 1 1 3 3 3 2 Protein of unknown function (DUF1258) Nucleoporin_N PF08801.6 ETO28308.1 - 1e-07 31.0 13.8 0.0077 15.0 1.0 5.3 1 1 5 6 6 6 3 Nup133 N terminal like PD40 PF07676.7 ETO28308.1 - 3.6e-07 29.6 12.5 1.8 8.3 0.0 6.9 7 0 0 7 7 7 3 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO28308.1 - 8e-06 24.3 1.9 0.44 8.8 0.0 3.1 1 1 2 3 3 3 3 Cytochrome D1 heme domain Gmad1 PF10647.4 ETO28308.1 - 1.3e-05 24.7 0.0 0.099 12.0 0.0 3.2 2 1 1 3 3 3 1 Lipoprotein LpqB beta-propeller domain Coatomer_WDAD PF04053.9 ETO28308.1 - 4.3e-05 22.4 0.8 0.0078 15.0 0.1 2.3 1 1 1 2 2 2 2 Coatomer WD associated region Nbas_N PF15492.1 ETO28308.1 - 0.00018 20.6 2.3 1.3 8.1 0.2 4.5 1 1 3 5 5 5 1 Neuroblastoma-amplified sequence, N terminal SGL PF08450.7 ETO28308.1 - 0.00069 19.0 0.2 0.028 13.8 0.0 2.6 2 1 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region DPPIV_N PF00930.16 ETO28308.1 - 0.0007 18.2 0.3 5.8 5.3 0.0 4.3 1 1 3 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region IKI3 PF04762.7 ETO28308.1 - 0.0015 16.4 1.7 0.16 9.7 0.1 3.1 1 1 1 3 3 3 1 IKI3 family Lipocalin_3 PF12702.2 ETO28308.1 - 0.0084 16.1 0.3 1.1 9.3 0.0 3.5 3 1 1 4 4 4 1 Lipocalin-like DUF3601 PF12208.3 ETO28308.1 - 0.013 15.3 0.0 9.2 6.2 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF3601) Proteasome_A_N PF10584.4 ETO28308.1 - 0.033 13.4 7.6 11 5.4 0.1 5.0 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Hira PF07569.6 ETO28308.1 - 0.035 13.3 0.6 0.67 9.1 0.0 3.1 1 1 2 4 4 4 0 TUP1-like enhancer of split gag_pre-integrs PF13976.1 ETO28308.1 - 0.14 11.8 1.4 3.4 7.3 0.0 3.8 6 0 0 6 6 5 0 GAG-pre-integrase domain TFIIIC_delta PF12657.2 ETO28308.1 - 0.55 9.9 3.9 2.2 7.9 0.1 3.1 1 1 2 4 4 4 0 Transcription factor IIIC subunit delta N-term Kelch_1 PF01344.20 ETO28309.1 - 5.7e-11 41.7 1.7 2.4e-06 26.9 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO28309.1 - 1.4e-09 37.7 3.1 0.00028 20.9 0.0 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO28309.1 - 1e-06 28.5 1.0 0.003 17.4 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 ETO28309.1 - 6.9e-06 25.6 0.4 0.013 15.2 0.0 2.7 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 ETO28309.1 - 0.00053 20.0 0.0 0.0039 17.3 0.0 2.3 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO28309.1 - 0.0018 18.0 0.2 0.51 10.1 0.0 3.2 2 1 1 3 3 3 1 Galactose oxidase, central domain PBP1_TM PF14812.1 ETO28310.1 - 0.0039 17.4 10.4 0.013 15.8 0.3 2.6 2 0 0 2 2 2 2 Transmembrane domain of transglycosylase PBP1 at N-terminal Mucin PF01456.12 ETO28310.1 - 0.56 9.9 15.2 0.26 11.0 8.4 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein SSP160 PF06933.6 ETO28310.1 - 5 4.9 11.7 7.1 4.4 8.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 ETO28310.1 - 6.8 6.4 12.1 4.5 7.0 6.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Dynamin_N PF00350.18 ETO28311.1 - 1.1e-05 25.3 0.7 1.7e-05 24.7 0.5 1.4 1 0 0 1 1 1 1 Dynamin family GTP_EFTU PF00009.22 ETO28311.1 - 0.0043 16.5 0.2 0.0092 15.4 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF3782 PF12644.2 ETO28312.1 - 0.0014 18.3 0.0 0.041 13.6 0.0 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3782) MerR-DNA-bind PF09278.6 ETO28312.1 - 0.45 10.9 4.3 1.2 9.5 0.5 2.6 2 0 0 2 2 2 0 MerR, DNA binding V_ATPase_I PF01496.14 ETO28312.1 - 1.2 6.8 10.4 0.056 11.3 3.6 1.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family YebO PF13974.1 ETO28312.1 - 8.2 6.2 10.9 16 5.3 1.9 3.1 2 1 1 3 3 3 0 YebO-like protein Mitofilin PF09731.4 ETO28313.1 - 1.8e-09 36.8 1.3 2.5e-09 36.3 0.9 1.3 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF3964 PF13107.1 ETO28313.1 - 0.011 16.0 0.1 0.019 15.1 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3964) Uteroglobin PF01099.12 ETO28313.1 - 0.017 14.9 0.3 0.045 13.5 0.2 1.7 1 0 0 1 1 1 0 Uteroglobin family zf-C4H2 PF10146.4 ETO28313.1 - 0.022 14.7 0.9 0.027 14.4 0.6 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein PGC7_Stella PF15549.1 ETO28313.1 - 0.057 13.3 0.5 0.11 12.4 0.3 1.5 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain Rap_GAP PF02145.10 ETO28314.1 - 7.4e-48 162.4 0.0 1.3e-47 161.5 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Hep_59 PF07052.6 ETO28314.1 - 0.72 10.2 4.7 1.3 9.4 2.2 2.3 1 1 1 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 Phage_holin_4 PF05105.7 ETO28315.1 - 0.085 12.5 0.1 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 Holin family FAT PF02259.18 ETO28318.1 - 3.8e-61 207.0 32.5 1e-45 156.3 3.2 3.7 2 1 1 3 3 3 2 FAT domain Rapamycin_bind PF08771.6 ETO28318.1 - 1.3e-17 63.6 11.2 1.3e-17 63.6 7.8 4.2 3 1 0 3 3 3 1 Rapamycin binding domain Pex14_N PF04695.8 ETO28318.1 - 0.07 13.1 20.2 2 8.4 1.6 3.8 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3385 PF11865.3 ETO28319.1 - 4.1e-10 39.8 15.2 3.4e-05 23.8 0.3 5.2 6 1 0 6 6 6 2 Domain of unknown function (DUF3385) HEAT_2 PF13646.1 ETO28319.1 - 1.3e-08 34.9 0.1 0.0074 16.5 0.0 5.1 4 1 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 ETO28319.1 - 2.1e-06 28.0 5.4 2 9.0 0.0 5.8 4 3 2 6 6 6 3 HEAT-like repeat Arm PF00514.18 ETO28319.1 - 0.0055 16.4 6.2 0.36 10.7 0.0 5.4 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT PF02985.17 ETO28319.1 - 0.033 14.2 7.3 1.6 8.9 0.0 5.5 5 0 0 5 5 5 0 HEAT repeat ASFV_J13L PF05568.6 ETO28321.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.4 1 1 0 1 1 1 0 African swine fever virus J13L protein DUF1031 PF06275.6 ETO28325.1 - 0.22 11.5 3.6 0.87 9.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1031) Pox_RNA_Pol_19 PF05320.7 ETO28326.1 - 0.033 13.9 0.3 0.039 13.6 0.2 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit IL17 PF06083.6 ETO28326.1 - 0.16 12.0 0.7 0.6 10.2 0.0 2.1 1 1 0 2 2 2 0 Interleukin-17 PM0188 PF11477.3 ETO28326.1 - 0.38 9.5 8.3 0.29 9.8 4.7 1.3 1 1 0 1 1 1 0 Sialyltransferase PMO188 APG6 PF04111.7 ETO28327.1 - 0.0065 15.5 17.3 0.0065 15.5 12.0 2.4 2 1 1 3 3 3 1 Autophagy protein Apg6 UBN2_2 PF14227.1 ETO28327.1 - 0.0087 15.6 5.8 0.0087 15.6 4.0 1.9 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type Methyltransf_30 PF05430.6 ETO28327.1 - 0.26 10.9 1.7 0.79 9.3 0.0 2.6 2 1 1 3 3 3 0 S-adenosyl-L-methionine-dependent methyltransferase CENP-F_leu_zip PF10473.4 ETO28327.1 - 3.6 7.4 25.0 1 9.2 11.1 2.8 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.10 ETO28327.1 - 9.2 5.8 15.0 0.27 10.7 5.3 2.3 3 0 0 3 3 3 0 Septum formation initiator OMP_b-brl PF13505.1 ETO28328.1 - 4.4e-11 43.0 4.8 8.3e-11 42.1 3.3 1.4 1 1 0 1 1 1 1 Outer membrane protein beta-barrel domain Opacity PF02462.10 ETO28328.1 - 0.00068 19.5 0.2 0.0013 18.6 0.2 1.4 1 0 0 1 1 1 1 Opacity family porin protein OmpA_membrane PF01389.12 ETO28328.1 - 0.00093 18.7 0.1 0.0014 18.1 0.1 1.3 1 0 0 1 1 1 1 OmpA-like transmembrane domain Surface_Ag_2 PF01617.12 ETO28328.1 - 0.011 14.8 0.5 0.026 13.7 0.4 1.5 1 0 0 1 1 1 0 Surface antigen TMEM237 PF15383.1 ETO28329.1 - 0.11 11.5 0.2 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 237 ubiquitin PF00240.18 ETO28331.1 - 5.3e-13 48.1 1.6 7.3e-13 47.7 1.1 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 ETO28331.1 - 2.7e-10 39.7 1.9 3.7e-10 39.3 1.3 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 ETO28331.1 - 0.00072 19.6 0.0 0.00073 19.6 0.0 1.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.1 ETO28331.1 - 0.012 15.7 0.1 0.016 15.4 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 ETO28331.1 - 0.046 13.6 0.4 0.18 11.7 0.3 1.8 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like CENP-F_N PF10481.4 ETO28333.1 - 3 7.1 6.0 5.2 6.3 1.1 2.1 2 0 0 2 2 2 0 Cenp-F N-terminal domain DUF4083 PF13314.1 ETO28334.1 - 0.09 12.6 2.2 0.1 12.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Ras PF00071.17 ETO28335.1 - 7.8e-12 44.8 0.2 1.8e-05 24.2 0.0 3.4 1 1 0 2 2 2 2 Ras family Miro PF08477.8 ETO28335.1 - 2.1e-07 31.4 0.0 1.1e-06 29.1 0.0 2.2 2 1 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 ETO28335.1 - 2.6e-05 24.1 0.1 0.00035 20.5 0.0 2.6 2 1 1 3 3 3 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 ETO28335.1 - 0.088 12.6 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Dynamin family C2 PF00168.25 ETO28339.1 - 2.5e-06 27.2 0.7 2.5e-06 27.2 0.5 2.2 2 0 0 2 2 2 1 C2 domain Myosin_tail_1 PF01576.14 ETO28339.1 - 3.4e-05 21.8 20.7 4.4e-05 21.4 14.4 1.1 1 0 0 1 1 1 1 Myosin tail DivIC PF04977.10 ETO28339.1 - 0.0054 16.1 2.2 0.0054 16.1 1.5 4.3 1 1 3 4 4 4 1 Septum formation initiator DUF1192 PF06698.6 ETO28339.1 - 0.0062 16.3 1.4 0.0062 16.3 1.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) TMF_DNA_bd PF12329.3 ETO28339.1 - 0.018 14.8 13.8 0.018 14.8 9.6 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding WD40_alt PF14077.1 ETO28339.1 - 0.031 13.8 0.1 0.14 11.8 0.1 2.1 1 0 0 1 1 1 0 Alternative WD40 repeat motif Reo_sigmaC PF04582.7 ETO28339.1 - 0.053 12.6 14.0 0.09 11.9 9.1 1.6 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 ETO28339.1 - 0.096 12.4 11.1 0.029 14.1 4.1 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Titin_Z PF09042.6 ETO28339.1 - 0.32 10.6 10.5 0.29 10.7 5.0 2.5 1 1 1 2 2 2 0 Titin Z DivIVA PF05103.8 ETO28339.1 - 0.58 10.2 23.2 2.2 8.3 2.4 2.6 1 1 1 2 2 2 0 DivIVA protein GAS PF13851.1 ETO28339.1 - 1.3 8.1 22.2 1.3 8.2 9.7 2.5 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding COG2 PF06148.6 ETO28339.1 - 1.3 8.8 12.1 1.4 8.7 2.9 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 IncA PF04156.9 ETO28339.1 - 1.5 8.3 25.5 1.4 8.4 10.6 2.1 1 1 1 2 2 2 0 IncA protein DUF972 PF06156.8 ETO28339.1 - 2.4 8.5 21.8 2.3 8.6 6.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF4559 PF15112.1 ETO28339.1 - 2.5 7.1 16.1 7.7 5.5 10.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) Jnk-SapK_ap_N PF09744.4 ETO28339.1 - 2.8 7.9 16.0 1.4 8.9 0.6 2.4 1 1 0 2 2 2 0 JNK_SAPK-associated protein-1 Cortex-I_coil PF09304.5 ETO28339.1 - 5.9 6.9 25.3 0.038 14.0 5.1 3.0 1 1 2 3 3 3 0 Cortexillin I, coiled coil Rabaptin PF03528.10 ETO28339.1 - 7.8 6.4 21.1 0.34 10.8 7.4 2.8 1 1 2 3 3 3 0 Rabaptin APG6 PF04111.7 ETO28339.1 - 7.9 5.4 24.9 0.4 9.6 10.6 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 His_Phos_2 PF00328.17 ETO28340.1 - 6.9e-22 78.2 0.0 1.1e-20 74.2 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF4361 PF14274.1 ETO28341.1 - 0.0048 16.5 4.2 0.0061 16.2 2.9 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4361) Adaptin_binding PF10199.4 ETO28341.1 - 0.061 13.6 1.7 0.081 13.2 1.2 1.1 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 PAP_RNA-bind PF04926.10 ETO28341.1 - 0.19 11.2 6.0 0.21 11.1 4.1 1.1 1 0 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain LMF1 PF06762.9 ETO28342.1 - 8e-20 70.9 1.2 2.7e-16 59.3 0.0 2.2 1 1 1 2 2 2 2 Lipase maturation factor Pkinase PF00069.20 ETO28343.1 - 1.3e-69 234.3 0.1 1.3e-69 234.3 0.1 2.5 3 2 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO28343.1 - 3.6e-31 108.1 0.0 1e-30 106.6 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase COPIIcoated_ERV PF07970.7 ETO28344.1 - 5.3 6.5 8.2 2.2 7.8 0.5 2.8 2 1 1 3 3 3 0 Endoplasmic reticulum vesicle transporter Aminotran_3 PF00202.16 ETO28346.1 - 3.6e-10 39.2 0.0 6.5e-10 38.3 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-III Aminotran_3 PF00202.16 ETO28347.1 - 5.3e-23 81.3 0.0 6e-23 81.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III SAM_2 PF07647.12 ETO28348.1 - 2.6e-11 43.2 0.3 4.5e-11 42.4 0.2 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO28348.1 - 4.2e-10 39.6 0.4 7.8e-10 38.7 0.3 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Striatin PF08232.7 ETO28348.1 - 0.0086 16.3 4.8 0.0086 16.3 3.3 2.7 3 0 0 3 3 3 1 Striatin family bZIP_1 PF00170.16 ETO28348.1 - 0.043 13.7 1.1 0.043 13.7 0.7 2.5 2 0 0 2 2 2 0 bZIP transcription factor Allexi_40kDa PF05549.6 ETO28348.1 - 1.3 8.2 8.9 0.9 8.7 5.2 1.5 1 1 0 1 1 1 0 Allexivirus 40kDa protein Muted PF14942.1 ETO28348.1 - 1.8 8.4 9.9 3.3 7.5 4.2 2.1 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein DUF342 PF03961.8 ETO28348.1 - 2.5 6.4 10.6 1.3 7.3 5.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Fib_alpha PF08702.5 ETO28348.1 - 5 7.2 14.4 0.27 11.3 2.9 3.0 1 1 4 5 5 5 0 Fibrinogen alpha/beta chain family DUF2681 PF10883.3 ETO28348.1 - 8.6 6.6 10.1 2.9 8.1 3.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) V_ATPase_I PF01496.14 ETO28348.1 - 8.6 4.0 11.9 1.7 6.3 5.7 1.7 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family TMPIT PF07851.8 ETO28348.1 - 9.3 5.2 8.6 10 5.0 3.5 2.1 2 0 0 2 2 2 0 TMPIT-like protein Pkinase PF00069.20 ETO28349.1 - 9.3e-08 31.5 0.2 2e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO28349.1 - 3.1e-07 29.7 0.1 8.8e-07 28.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase m04gp34like PF12216.3 ETO28349.1 - 0.013 14.8 0.1 0.031 13.6 0.1 1.6 1 0 0 1 1 1 0 Immune evasion protein FTR1 PF03239.9 ETO28349.1 - 0.36 9.7 1.9 0.45 9.4 0.2 1.9 2 0 0 2 2 2 0 Iron permease FTR1 family MMS1_N PF10433.4 ETO28350.1 - 1.2e-66 224.8 0.0 3.8e-66 223.2 0.0 1.8 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 ETO28350.1 - 2.2e-63 214.2 1.4 5e-63 213.1 1.0 1.5 1 0 0 1 1 1 1 CPSF A subunit region RasGAP PF00616.14 ETO28351.1 - 1.2e-23 83.8 1.3 7.4e-23 81.2 0.0 2.6 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 ETO28351.1 - 5.2e-09 35.9 6.8 5.2e-09 35.9 4.7 3.2 3 1 1 4 4 4 1 RasGAP C-terminus NPV_P10 PF05531.7 ETO28351.1 - 0.0085 16.3 0.4 0.31 11.3 0.0 3.3 3 0 0 3 3 3 1 Nucleopolyhedrovirus P10 protein DUF1910 PF08928.5 ETO28351.1 - 0.71 9.9 5.9 0.32 11.0 0.7 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1910) RasGAP PF00616.14 ETO28352.1 - 6.5e-10 38.9 0.3 8.3e-10 38.6 0.2 1.2 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase Imm29 PF15575.1 ETO28353.1 - 0.0013 18.3 0.4 0.0013 18.3 0.3 1.7 1 1 1 2 2 2 1 Immunity protein 29 TPR_MLP1_2 PF07926.7 ETO28353.1 - 0.0046 16.7 35.3 0.0046 16.7 24.4 2.0 2 1 1 3 3 3 1 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.14 ETO28353.1 - 0.14 9.9 18.7 0.23 9.2 12.8 1.4 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Mnd1 PF03962.10 ETO28353.1 - 0.24 11.0 26.0 3.4 7.2 0.5 2.2 1 1 2 3 3 3 0 Mnd1 family DUF2120 PF09893.4 ETO28353.1 - 0.27 11.1 2.0 1.3 8.9 0.7 2.1 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) DUF812 PF05667.6 ETO28353.1 - 0.27 9.6 24.9 0.37 9.2 17.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) His_Phos_1 PF00300.17 ETO28353.1 - 0.31 11.1 5.8 0.28 11.2 3.1 1.6 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) OmpH PF03938.9 ETO28353.1 - 0.41 10.5 29.8 2.1 8.2 5.5 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Phage_Mu_F PF04233.9 ETO28353.1 - 0.49 10.9 4.9 4.4 7.8 3.4 2.2 1 1 0 1 1 1 0 Phage Mu protein F like protein DUF3919 PF13057.1 ETO28353.1 - 0.52 9.7 13.6 2 7.8 9.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3919) TEX19 PF15553.1 ETO28353.1 - 0.58 10.0 4.7 0.94 9.3 3.3 1.3 1 0 0 1 1 1 0 Testis-expressed protein 19 Asp-B-Hydro_N PF05279.6 ETO28353.1 - 0.63 9.8 9.2 0.78 9.5 6.4 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Reprolysin_5 PF13688.1 ETO28353.1 - 0.85 9.5 6.6 3 7.7 0.2 2.2 1 1 1 2 2 2 0 Metallo-peptidase family M12 TBPIP PF07106.8 ETO28353.1 - 1.1 8.8 28.6 0.82 9.1 2.7 2.4 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) 60KD_IMP PF02096.15 ETO28353.1 - 3 7.4 12.1 1.3 8.6 0.1 2.4 2 0 0 2 2 2 0 60Kd inner membrane protein RHD PF00554.17 ETO28353.1 - 3.1 7.4 10.9 0.67 9.6 3.1 2.1 1 1 1 2 2 2 0 Rel homology domain (RHD) Acetyltransf_1 PF00583.19 ETO28354.1 - 1.1e-14 54.1 0.0 2e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 ETO28354.1 - 4.7e-11 42.7 0.0 6.6e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 ETO28354.1 - 1e-09 38.4 0.0 1.5e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETO28354.1 - 2.6e-09 36.7 0.0 4.5e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 ETO28354.1 - 4.3e-07 30.1 0.0 6.5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETO28354.1 - 7.4e-06 26.0 0.0 1.1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 ETO28354.1 - 4.3e-05 23.5 0.2 6.2e-05 22.9 0.2 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETO28354.1 - 0.00098 18.9 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 ETO28354.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase WD40 PF00400.27 ETO28357.1 - 1.2e-52 173.9 6.5 7e-13 47.9 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO28357.1 - 2.7e-07 30.4 0.1 0.0013 18.4 0.0 2.9 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO28357.1 - 5e-07 28.3 0.1 0.00033 19.0 0.0 2.7 1 1 2 3 3 3 3 Cytochrome D1 heme domain PD40 PF07676.7 ETO28357.1 - 6.9e-06 25.6 0.6 0.0029 17.2 0.0 3.6 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO28357.1 - 2.5e-05 22.6 6.2 0.24 9.5 0.1 4.5 1 1 3 5 5 5 3 Nucleoporin Nup120/160 VID27 PF08553.5 ETO28357.1 - 0.00038 18.8 0.0 0.0033 15.7 0.0 2.2 3 0 0 3 3 3 1 VID27 cytoplasmic protein DUF3312 PF11768.3 ETO28357.1 - 0.04 12.1 0.1 0.19 9.8 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3312) Hira PF07569.6 ETO28357.1 - 0.23 10.6 1.4 10 5.2 0.1 3.2 2 1 1 3 3 3 0 TUP1-like enhancer of split Proteasome_A_N PF10584.4 ETO28357.1 - 2.7 7.4 4.5 63 3.0 0.0 3.8 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature CCDC71L PF15374.1 ETO28358.1 - 0.41 9.9 26.0 0.66 9.2 18.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L TFIIA PF03153.8 ETO28358.1 - 0.73 9.6 29.1 1.1 9.1 20.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S64 PF08192.6 ETO28358.1 - 5.5 5.1 23.5 7.2 4.8 16.3 1.2 1 0 0 1 1 1 0 Peptidase family S64 Vma12 PF11712.3 ETO28359.1 - 0.52 10.0 0.0 0.52 10.0 0.0 2.7 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase WD40 PF00400.27 ETO28360.1 - 1.5e-21 75.3 12.3 1.8e-07 30.7 0.1 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Inos-1-P_synth PF01658.12 ETO28360.1 - 2.2 8.1 4.5 0.96 9.3 0.1 2.2 2 0 0 2 2 2 0 Myo-inositol-1-phosphate synthase zf-TRAF PF02176.13 ETO28361.1 - 1.5e-11 44.4 6.4 1.5e-11 44.4 4.4 2.3 2 0 0 2 2 2 1 TRAF-type zinc finger PH PF00169.24 ETO28361.1 - 2.5e-05 24.3 1.6 3.4e-05 24.0 0.1 2.0 2 1 0 2 2 2 1 PH domain PH_11 PF15413.1 ETO28361.1 - 6.2e-05 23.2 0.1 6.2e-05 23.2 0.1 3.1 2 1 0 2 2 2 1 Pleckstrin homology domain TelA PF05816.6 ETO28361.1 - 0.00039 19.2 4.6 0.0006 18.6 3.2 1.2 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) PH_3 PF14593.1 ETO28361.1 - 0.0017 18.1 3.3 0.0027 17.5 0.2 2.4 2 0 0 2 2 2 1 PH domain PH_8 PF15409.1 ETO28361.1 - 0.059 13.4 2.0 0.068 13.2 0.1 2.1 2 1 1 3 3 3 0 Pleckstrin homology domain DUF4047 PF13256.1 ETO28361.1 - 0.099 12.6 6.5 0.025 14.5 1.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) Reo_sigmaC PF04582.7 ETO28361.1 - 0.36 9.9 6.0 0.48 9.5 4.2 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 ETO28361.1 - 0.66 9.7 5.2 0.23 11.2 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) IBR PF01485.16 ETO28361.1 - 0.87 9.5 8.0 21 5.1 3.7 2.5 2 0 0 2 2 2 0 IBR domain IncA PF04156.9 ETO28361.1 - 3.1 7.3 10.9 28 4.2 7.6 2.4 1 1 0 1 1 1 0 IncA protein G-patch PF01585.18 ETO28362.1 - 2.2e-08 33.7 0.6 4.9e-08 32.6 0.4 1.6 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.3 ETO28362.1 - 6.4e-07 29.4 10.1 6.4e-07 29.4 7.0 3.8 2 1 1 3 3 3 1 Tuftelin interacting protein N terminal Rab3-GTPase_cat PF13890.1 ETO28363.1 - 1.3e-07 31.1 1.3 1.8e-07 30.6 0.1 1.9 2 0 0 2 2 2 1 Rab3 GTPase-activating protein catalytic subunit CDC45 PF02724.9 ETO28363.1 - 0.051 11.6 2.8 0.072 11.1 1.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Gly-zipper_OmpA PF13436.1 ETO28364.1 - 0.018 14.7 0.0 0.045 13.4 0.0 1.7 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Dak2 PF02734.12 ETO28364.1 - 0.23 11.0 3.2 0.19 11.4 0.6 1.9 2 0 0 2 2 2 0 DAK2 domain Spectrin PF00435.16 ETO28364.1 - 0.52 10.6 23.0 1.7 8.9 1.4 3.5 2 1 1 3 3 3 0 Spectrin repeat MCPsignal PF00015.16 ETO28364.1 - 0.72 9.3 6.6 6.2 6.2 0.1 2.4 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Orbi_VP5 PF00901.12 ETO28364.1 - 4.2 5.4 20.7 0.65 8.1 9.1 2.1 2 0 0 2 2 2 0 Orbivirus outer capsid protein VP5 YtzH PF14165.1 ETO28364.1 - 5 7.4 13.3 0.47 10.7 0.3 4.2 3 1 0 4 4 4 0 YtzH-like protein HSCB_C PF07743.8 ETO28364.1 - 8.2 6.9 17.3 0.037 14.4 3.3 3.3 3 1 0 3 3 3 0 HSCB C-terminal oligomerisation domain Allexi_40kDa PF05549.6 ETO28364.1 - 9 5.4 12.3 0.15 11.3 2.4 2.3 2 1 1 3 3 3 0 Allexivirus 40kDa protein DivIC PF04977.10 ETO28365.1 - 0.031 13.7 6.7 0.23 10.9 0.2 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF4196 PF13846.1 ETO28365.1 - 0.043 14.1 0.2 0.074 13.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4196) LRR_4 PF12799.2 ETO28365.1 - 0.098 12.3 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) RasGAP_C PF03836.10 ETO28365.1 - 0.12 12.1 3.3 0.62 9.7 0.2 2.0 2 0 0 2 2 2 0 RasGAP C-terminus BBP1_C PF15272.1 ETO28365.1 - 0.38 10.2 4.1 1.1 8.7 2.8 1.7 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal TMF_TATA_bd PF12325.3 ETO28365.1 - 0.46 10.2 4.4 0.33 10.6 0.3 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding SURF6 PF04935.7 ETO28365.1 - 2.4 7.4 6.4 0.7 9.1 1.7 1.9 2 0 0 2 2 2 0 Surfeit locus protein 6 Pox_A_type_inc PF04508.7 ETO28365.1 - 8.4 6.4 9.5 0.25 11.2 0.5 2.9 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Nucleoplasmin PF03066.10 ETO28367.1 - 0.0044 16.5 14.2 0.0044 16.5 9.8 5.0 4 1 1 5 5 5 1 Nucleoplasmin MIP-T3 PF10243.4 ETO28367.1 - 1.6 7.0 54.9 0.96 7.8 19.5 3.1 3 0 0 3 3 3 0 Microtubule-binding protein MIP-T3 Kelch_2 PF07646.10 ETO28368.1 - 0.033 13.9 2.9 18 5.2 0.6 4.1 3 1 0 3 3 3 0 Kelch motif TRAP_alpha PF03896.11 ETO28370.1 - 0.0084 15.1 1.9 0.014 14.4 1.3 1.4 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit HAD PF12710.2 ETO28370.1 - 0.039 14.1 0.3 0.054 13.6 0.2 1.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Sporozoite_P67 PF05642.6 ETO28370.1 - 0.28 8.9 11.2 0.44 8.3 7.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CAF1A PF12253.3 ETO28370.1 - 0.4 10.8 11.4 0.052 13.6 4.5 2.0 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A DUF506 PF04720.7 ETO28370.1 - 0.81 9.2 10.1 1.2 8.7 4.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF506) Nucleoplasmin PF03066.10 ETO28370.1 - 1 8.8 9.6 0.11 12.0 3.4 1.9 2 0 0 2 2 2 0 Nucleoplasmin DUF2457 PF10446.4 ETO28370.1 - 1.1 7.9 15.4 0.09 11.4 7.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) FAM176 PF14851.1 ETO28370.1 - 2.3 7.8 6.9 0.5 10.0 1.7 2.1 2 1 0 2 2 2 0 FAM176 family E1-E2_ATPase PF00122.15 ETO28371.1 - 1.9e-05 23.7 0.0 2.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 E1-E2 ATPase Pex14_N PF04695.8 ETO28371.1 - 0.027 14.5 1.6 0.042 13.8 1.1 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Secretin_N_2 PF07655.8 ETO28371.1 - 0.11 12.9 21.1 0.18 12.1 14.6 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain PH_4 PF15404.1 ETO28371.1 - 0.21 11.1 3.0 0.33 10.4 2.1 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain Tim54 PF11711.3 ETO28371.1 - 0.28 9.7 2.1 0.4 9.2 1.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Menin PF05053.8 ETO28371.1 - 3.6 5.6 6.7 4.2 5.4 4.6 1.1 1 0 0 1 1 1 0 Menin Nup96 PF12110.3 ETO28372.1 - 4.7e-09 35.7 0.2 0.00084 18.5 0.0 2.5 2 0 0 2 2 2 2 Nuclear protein 96 Herpes_capsid PF06112.6 ETO28372.1 - 0.58 10.1 15.2 1.7 8.6 10.6 1.8 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein PUB PF09409.5 ETO28374.1 - 0.0041 16.8 2.7 0.01 15.5 0.7 2.5 2 1 0 2 2 2 1 PUB domain ACDC PF14733.1 ETO28374.1 - 0.21 11.7 0.0 0.21 11.7 0.0 2.8 2 1 0 2 2 2 0 AP2-coincident C-terminal CobT PF06213.7 ETO28375.1 - 0.0018 17.5 6.1 0.0031 16.6 4.2 1.4 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT TFIIA PF03153.8 ETO28375.1 - 0.0023 17.8 5.6 0.004 17.1 3.9 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.9 ETO28375.1 - 0.0085 14.1 3.3 0.012 13.6 2.3 1.2 1 0 0 1 1 1 1 CDC45-like protein RNA_pol_3_Rpc31 PF11705.3 ETO28375.1 - 0.061 13.2 15.8 0.11 12.4 10.9 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Daxx PF03344.10 ETO28375.1 - 0.13 10.7 14.5 0.17 10.3 10.1 1.1 1 0 0 1 1 1 0 Daxx Family Nucleoplasmin PF03066.10 ETO28375.1 - 0.16 11.4 8.7 0.34 10.4 6.1 1.5 1 0 0 1 1 1 0 Nucleoplasmin TRAP_alpha PF03896.11 ETO28375.1 - 0.25 10.3 5.0 0.47 9.3 3.5 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit HSP90 PF00183.13 ETO28375.1 - 1.1 7.5 9.3 1.8 6.8 6.5 1.3 1 0 0 1 1 1 0 Hsp90 protein Pox_Ag35 PF03286.9 ETO28375.1 - 1.1 8.7 10.1 2.3 7.7 7.0 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM176 PF14851.1 ETO28375.1 - 1.3 8.7 7.8 0.16 11.6 2.4 1.8 2 0 0 2 2 2 0 FAM176 family Sigma70_ner PF04546.8 ETO28375.1 - 1.4 8.5 14.3 0.14 11.7 4.8 2.6 3 0 0 3 3 3 0 Sigma-70, non-essential region DUF2457 PF10446.4 ETO28375.1 - 1.5 7.4 23.5 2.4 6.7 16.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Menin PF05053.8 ETO28375.1 - 7.2 4.6 7.9 11 3.9 5.5 1.2 1 0 0 1 1 1 0 Menin Neur_chan_memb PF02932.11 ETO28376.1 - 0.016 15.1 4.1 0.025 14.4 2.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Secretin_N_2 PF07655.8 ETO28376.1 - 0.77 10.1 15.6 2 8.8 10.8 1.7 1 0 0 1 1 1 0 Secretin N-terminal domain DUF912 PF06024.7 ETO28376.1 - 6 6.9 17.3 0.64 10.0 7.2 2.8 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PI3_PI4_kinase PF00454.22 ETO28377.1 - 3.7e-21 75.6 0.0 2.2e-10 40.4 0.0 2.6 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase RPM2 PF08579.6 ETO28377.1 - 0.019 15.0 0.2 2.7 8.1 0.1 2.7 1 1 1 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) fn3 PF00041.16 ETO28378.1 - 4.3e-07 29.9 1.2 4.3e-07 29.9 0.8 2.6 2 1 0 2 2 2 1 Fibronectin type III domain DUF3500 PF12006.3 ETO28378.1 - 0.0049 15.8 0.1 0.01 14.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) Esterase PF00756.15 ETO28379.1 - 4e-10 39.5 0.1 5e-09 35.9 0.1 2.1 1 1 0 1 1 1 1 Putative esterase HALZ PF02183.13 ETO28380.1 - 0.018 14.7 1.7 0.018 14.7 1.1 3.5 2 1 0 2 2 2 0 Homeobox associated leucine zipper Reprolysin_3 PF13582.1 ETO28380.1 - 0.3 11.6 9.2 1.2 9.6 6.4 2.0 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like AcetylCoA_hydro PF02550.10 ETO28381.1 - 2.4e-09 37.2 0.0 5.5e-09 36.0 0.0 1.5 1 1 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain Pkinase PF00069.20 ETO28382.1 - 9.2e-40 136.4 1.3 5.3e-27 94.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO28382.1 - 1.3e-15 57.1 0.3 8.8e-09 34.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase PYST-C1 PF09690.5 ETO28382.1 - 0.32 10.6 4.4 0.58 9.8 1.0 2.3 2 0 0 2 2 2 0 Plasmodium yoelii subtelomeric region (PYST-C1) Pkinase PF00069.20 ETO28383.1 - 0.0081 15.3 1.1 0.03 13.4 0.4 2.0 2 0 0 2 2 2 1 Protein kinase domain Macoilin PF09726.4 ETO28383.1 - 6.1 4.9 19.4 8.1 4.5 13.5 1.1 1 0 0 1 1 1 0 Transmembrane protein FH2 PF02181.18 ETO28384.1 - 1.9e-14 53.3 4.7 1.9e-14 53.3 3.3 4.5 3 2 2 5 5 5 1 Formin Homology 2 Domain DUF2360 PF10152.4 ETO28384.1 - 2.1e-10 41.0 50.4 0.00051 20.3 0.2 7.3 5 1 1 6 6 6 4 Predicted coiled-coil domain-containing protein (DUF2360) FH2 PF02181.18 ETO28385.1 - 1.3e-25 90.0 2.3 1.7e-25 89.6 1.6 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain RmuC PF02646.11 ETO28385.1 - 5.8e-05 22.0 1.1 7.2e-05 21.7 0.8 1.2 1 0 0 1 1 1 1 RmuC family YgaB PF14182.1 ETO28385.1 - 0.0023 18.1 0.4 0.0054 16.9 0.1 1.8 2 0 0 2 2 2 1 YgaB-like protein EzrA PF06160.7 ETO28385.1 - 0.0025 16.0 2.0 0.0031 15.7 1.4 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA MCPsignal PF00015.16 ETO28385.1 - 0.01 15.4 0.0 0.013 15.0 0.0 1.1 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain ApoLp-III PF07464.6 ETO28385.1 - 0.028 14.4 0.9 0.047 13.7 0.6 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Ubiq_cyt_C_chap PF03981.7 ETO28385.1 - 0.029 14.2 0.1 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone DUF948 PF06103.6 ETO28385.1 - 0.032 14.0 0.7 0.05 13.4 0.5 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) FliD_C PF07195.7 ETO28385.1 - 0.034 13.4 1.5 0.043 13.1 1.1 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Phage_GPO PF05929.6 ETO28385.1 - 0.07 12.3 0.1 0.098 11.8 0.0 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase AAA_13 PF13166.1 ETO28385.1 - 0.073 11.5 1.6 0.088 11.2 1.1 1.1 1 0 0 1 1 1 0 AAA domain Tnp_P_element PF12017.3 ETO28385.1 - 0.084 12.0 0.4 0.12 11.5 0.3 1.2 1 0 0 1 1 1 0 Transposase protein DUF883 PF05957.8 ETO28385.1 - 0.099 13.0 0.8 0.2 12.0 0.4 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Bacillus_HBL PF05791.6 ETO28385.1 - 0.12 11.6 2.5 0.17 11.2 1.7 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) COG2 PF06148.6 ETO28385.1 - 0.13 12.1 1.1 0.29 11.0 0.7 1.6 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Plasmodium_Vir PF05795.6 ETO28386.1 - 2.5 7.1 5.9 3 6.9 4.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RNA_pol_Rpb1_R PF05001.8 ETO28386.1 - 7.8 6.9 14.4 0.29 11.3 3.0 2.6 2 0 0 2 2 2 0 RNA polymerase Rpb1 C-terminal repeat EF-hand_1 PF00036.27 ETO28388.1 - 1.4e-13 49.0 8.2 2.4e-07 29.5 0.3 3.8 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 ETO28388.1 - 2.3e-12 46.8 3.5 2.2e-08 34.1 1.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO28388.1 - 2.1e-11 42.6 5.9 4.1e-06 26.2 0.2 4.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 ETO28388.1 - 5.5e-07 29.0 6.2 0.056 13.0 0.2 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 ETO28388.1 - 2.6e-06 26.5 8.9 1.6e-05 24.0 0.8 3.6 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.2 ETO28388.1 - 0.00071 19.2 4.1 0.014 15.1 0.1 2.7 1 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 ETO28388.1 - 0.061 13.3 0.6 0.29 11.1 0.1 1.9 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF508 PF04370.7 ETO28389.1 - 0.022 14.3 0.3 0.038 13.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) WD40 PF00400.27 ETO28390.1 - 1.5e-36 122.9 20.0 3.7e-10 39.2 0.9 6.4 6 1 0 6 6 6 5 WD domain, G-beta repeat PQQ_2 PF13360.1 ETO28390.1 - 0.00023 20.7 0.4 0.054 12.9 0.1 3.0 2 1 0 2 2 2 2 PQQ-like domain Nup160 PF11715.3 ETO28390.1 - 0.82 7.7 6.7 0.26 9.3 0.0 2.4 2 1 1 3 3 3 0 Nucleoporin Nup120/160 GET2 PF08690.5 ETO28391.1 - 0.085 12.0 0.2 0.094 11.9 0.1 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 CAP_GLY PF01302.20 ETO28392.1 - 2.1e-33 113.8 2.8 1e-16 60.3 0.2 2.3 2 0 0 2 2 2 2 CAP-Gly domain Pkinase PF00069.20 ETO28392.1 - 0.031 13.4 0.1 0.031 13.4 0.1 2.0 2 0 0 2 2 2 0 Protein kinase domain Pkinase_Tyr PF07714.12 ETO28392.1 - 0.034 13.2 0.2 0.06 12.4 0.2 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase RabGAP-TBC PF00566.13 ETO28392.1 - 0.23 10.9 4.5 0.41 10.0 3.1 1.3 1 0 0 1 1 1 0 Rab-GTPase-TBC domain Pkinase PF00069.20 ETO28393.1 - 3.3e-44 151.0 0.2 1.4e-38 132.5 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain EF-hand_1 PF00036.27 ETO28393.1 - 6.5e-23 78.2 7.8 9.7e-06 24.5 0.2 4.6 4 0 0 4 4 4 4 EF hand Pkinase_Tyr PF07714.12 ETO28393.1 - 1.6e-21 76.5 0.0 2.9e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.1 ETO28393.1 - 4.7e-19 68.2 26.2 2e-08 34.2 2.4 4.3 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 ETO28393.1 - 8.2e-18 62.8 10.0 4.4e-06 25.7 0.3 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 ETO28393.1 - 2.2e-16 58.1 11.2 1.1e-05 24.8 0.4 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 ETO28393.1 - 2.3e-13 49.5 7.9 0.0045 16.5 0.0 4.6 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.2 ETO28393.1 - 2.8e-07 30.2 3.6 0.016 14.9 0.7 2.7 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Choline_kinase PF01633.15 ETO28393.1 - 0.0059 16.2 0.1 0.042 13.4 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.9 ETO28393.1 - 0.015 14.4 0.0 0.03 13.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SPARC_Ca_bdg PF10591.4 ETO28393.1 - 3.4 7.7 14.1 2.1 8.3 1.5 3.6 2 1 0 4 4 4 0 Secreted protein acidic and rich in cysteine Ca binding region zf-CHY PF05495.7 ETO28394.1 - 3.5e-12 46.3 28.4 3.5e-12 46.3 19.7 4.4 3 1 1 4 4 4 1 CHY zinc finger zf-RING_2 PF13639.1 ETO28394.1 - 2.3e-08 33.6 8.1 2.3e-08 33.6 5.6 4.4 1 1 3 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.1 ETO28394.1 - 2.1e-05 24.1 5.6 2.1e-05 24.1 3.9 4.8 1 1 3 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO28394.1 - 0.00012 22.0 8.8 0.00012 22.0 6.1 5.0 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO28394.1 - 0.002 17.7 8.1 0.002 17.7 5.6 5.6 1 1 3 4 4 4 1 zinc-RING finger domain Daxx PF03344.10 ETO28394.1 - 0.58 8.5 25.4 0.01 14.4 10.1 2.2 2 0 0 2 2 2 0 Daxx Family DUF148 PF02520.12 ETO28395.1 - 0.00013 21.7 3.7 0.00013 21.7 2.5 2.7 3 0 0 3 3 3 1 Domain of unknown function DUF148 O-FucT PF10250.4 ETO28396.1 - 1.6e-08 34.1 7.2 0.021 13.9 0.0 4.2 1 1 1 2 2 2 2 GDP-fucose protein O-fucosyltransferase Cyclin_N PF00134.18 ETO28397.1 - 4.1e-39 133.0 0.2 1e-38 131.7 0.1 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 ETO28397.1 - 8.2e-15 54.7 2.0 8.2e-15 54.7 1.4 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain DUF2457 PF10446.4 ETO28399.1 - 1.1 7.8 28.1 0.021 13.5 8.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) DUF883 PF05957.8 ETO28401.1 - 0.025 14.9 0.0 0.24 11.8 0.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) MerR-DNA-bind PF09278.6 ETO28401.1 - 3.3 8.1 5.2 6.1 7.3 0.5 2.8 3 0 0 3 3 3 0 MerR, DNA binding SIR2 PF02146.12 ETO28404.1 - 0.15 11.7 3.5 0.2 11.3 2.5 1.3 1 0 0 1 1 1 0 Sir2 family Pox_Ag35 PF03286.9 ETO28404.1 - 0.15 11.5 7.6 0.19 11.2 5.3 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF3166 PF11365.3 ETO28404.1 - 0.19 12.1 2.1 0.3 11.5 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3166) C9orf72-like PF15019.1 ETO28405.1 - 0.0063 15.7 1.0 0.022 13.9 0.6 1.8 1 1 1 2 2 2 1 C9orf72-like protein family LRR_4 PF12799.2 ETO28406.1 - 1.2e-13 50.2 18.8 1.8e-06 27.4 1.0 5.0 4 0 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO28406.1 - 1.1e-11 44.2 17.6 1e-08 34.7 1.9 4.2 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 ETO28406.1 - 0.036 14.1 21.3 10 6.5 0.0 6.9 6 0 0 6 6 6 0 Leucine Rich repeat LRR_7 PF13504.1 ETO28406.1 - 7.5 7.2 19.0 12 6.6 0.0 6.9 7 0 0 7 7 7 0 Leucine rich repeat Alpha_kinase PF02816.13 ETO28407.1 - 3.3e-08 33.4 2.0 7.5e-08 32.2 1.4 1.5 1 1 0 1 1 1 1 Alpha-kinase family Secretin_N_2 PF07655.8 ETO28408.1 - 2.9 8.3 11.7 6.1 7.3 8.1 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain Peptidase_S9 PF00326.16 ETO28409.1 - 3.4e-05 23.1 0.0 4.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETO28409.1 - 0.0026 17.4 0.0 0.0051 16.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF829 PF05705.9 ETO28409.1 - 0.036 13.7 0.2 0.054 13.1 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) DUF2920 PF11144.3 ETO28409.1 - 0.12 11.3 1.1 0.14 11.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Peptidase_C54 PF03416.14 ETO28410.1 - 4.8e-75 252.2 0.6 4.8e-75 252.2 0.4 1.5 2 0 0 2 2 2 1 Peptidase family C54 Peptidase_C78 PF07910.8 ETO28410.1 - 0.016 14.3 0.2 0.032 13.3 0.1 1.4 1 0 0 1 1 1 0 Peptidase family C78 DUF45 PF01863.12 ETO28410.1 - 0.048 13.4 0.7 0.11 12.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF45 Guanylate_cyc PF00211.15 ETO28411.1 - 2.1e-10 40.2 0.0 2.1e-06 27.2 0.0 2.1 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.1 ETO28412.1 - 3.1e-07 30.5 0.0 4.5e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain Guanylate_cyc PF00211.15 ETO28412.1 - 4.1e-06 26.2 0.0 7.6e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain AAA_22 PF13401.1 ETO28412.1 - 0.0094 16.0 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 ETO28412.1 - 0.021 14.5 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 ETO28412.1 - 0.024 14.3 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase DUF2075 PF09848.4 ETO28412.1 - 0.048 12.6 0.0 0.062 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF258 PF03193.11 ETO28412.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF815 PF05673.8 ETO28412.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.1 ETO28413.1 - 0.00026 21.0 0.1 0.0006 19.8 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain PI-PLC-X PF00388.14 ETO28414.1 - 0.0003 20.1 0.0 0.00059 19.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain YkuD_2 PF13645.1 ETO28415.1 - 0.028 13.6 0.1 0.034 13.3 0.1 1.2 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain DUF1754 PF08555.5 ETO28415.1 - 7.3 7.2 12.6 0.48 11.0 5.3 1.5 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) DUF3275 PF11679.3 ETO28416.1 - 0.011 15.3 0.2 0.021 14.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) S-antigen PF05756.6 ETO28416.1 - 4.4 7.3 6.0 0.56 10.2 0.3 2.2 2 0 0 2 2 2 0 S-antigen protein Cyclin_N PF00134.18 ETO28417.1 - 0.00013 21.5 0.1 0.00025 20.6 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_N PF00134.18 ETO28418.1 - 0.00051 19.5 0.1 0.0014 18.2 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain LMF1 PF06762.9 ETO28418.1 - 0.27 10.0 5.0 0.36 9.5 3.4 1.1 1 0 0 1 1 1 0 Lipase maturation factor EF-hand_7 PF13499.1 ETO28419.1 - 1.1e-23 83.1 6.4 5.1e-13 48.9 0.7 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 ETO28419.1 - 1.3e-22 77.2 12.8 4.5e-06 25.5 1.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 ETO28419.1 - 1.1e-20 72.9 5.7 1.6e-12 46.8 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO28419.1 - 3.1e-18 63.9 8.3 7.8e-06 25.3 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 ETO28419.1 - 9.4e-11 40.5 12.1 0.0018 17.4 0.8 4.6 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 ETO28419.1 - 7.5e-09 35.3 0.1 6.8e-08 32.3 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.4 ETO28419.1 - 2.8e-05 24.1 4.9 0.00047 20.1 1.0 2.4 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 ETO28419.1 - 0.009 15.6 0.9 6 6.5 0.0 3.1 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) Beta-lactamase2 PF13354.1 ETO28419.1 - 0.011 15.2 0.1 0.018 14.4 0.0 1.4 1 1 0 1 1 1 0 Beta-lactamase enzyme family EF-hand_like PF09279.6 ETO28419.1 - 0.03 14.3 0.6 0.087 12.8 0.2 2.0 1 1 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like TerB PF05099.8 ETO28419.1 - 0.065 12.9 0.1 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TerB EF-hand_4 PF12763.2 ETO28419.1 - 0.45 10.2 4.7 10 5.9 0.3 2.6 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand PrgI PF12666.2 ETO28420.1 - 3.6 7.7 8.4 13 6.0 3.2 2.3 2 0 0 2 2 2 0 PrgI family protein WD40 PF00400.27 ETO28421.1 - 1.2e-41 139.0 19.7 3.7e-11 42.4 0.2 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO28421.1 - 2.2e-07 29.4 7.4 0.25 9.4 0.2 4.3 1 1 1 3 3 3 3 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO28421.1 - 1.3e-05 25.5 1.7 1.3e-05 25.5 1.2 2.9 2 1 1 3 3 3 1 TRAF-type zinc finger DUF4140 PF13600.1 ETO28421.1 - 0.93 9.9 8.5 3.7 8.0 5.8 2.1 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) zf-C3HC4_2 PF13923.1 ETO28421.1 - 4.3 7.4 7.1 1.6 8.8 1.5 3.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_11 PF13414.1 ETO28422.1 - 1.2e-18 66.5 14.8 4e-13 48.8 0.5 5.6 5 0 0 5 5 5 3 TPR repeat TPR_2 PF07719.12 ETO28422.1 - 2.6e-18 64.4 22.9 2.6e-05 23.7 0.9 8.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.23 ETO28422.1 - 1.5e-17 62.3 23.2 1.1e-07 31.1 1.4 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO28422.1 - 1.6e-17 61.8 11.3 2.9e-05 23.5 0.4 6.7 6 0 0 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 ETO28422.1 - 9.3e-16 57.7 23.4 6.6e-11 42.1 2.4 5.0 4 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO28422.1 - 5.6e-14 52.2 2.3 0.0021 18.3 0.1 5.8 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 ETO28422.1 - 6.9e-14 51.5 14.7 2.2e-07 30.7 0.9 5.3 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO28422.1 - 2.9e-12 46.8 0.1 4.4e-05 24.0 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO28422.1 - 2.7e-10 39.9 1.3 0.0058 17.1 0.0 6.1 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO28422.1 - 7.8e-10 38.5 9.3 0.0024 18.1 0.0 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO28422.1 - 3.7e-07 29.8 5.5 5.7e-05 23.0 0.1 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO28422.1 - 8.9e-07 28.2 6.6 0.79 9.6 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO28422.1 - 0.0022 17.1 0.0 0.04 13.1 0.0 3.0 3 0 0 3 3 3 1 SHNi-TPR TPR_10 PF13374.1 ETO28422.1 - 0.012 15.5 0.6 8.6 6.4 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 ETO28422.1 - 0.013 15.5 0.2 0.75 9.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat FAM60A PF15396.1 ETO28422.1 - 0.035 13.8 4.6 0.072 12.8 3.2 1.4 1 0 0 1 1 1 0 Protein Family FAM60A DUF2201_N PF13203.1 ETO28422.1 - 0.039 13.1 0.7 0.059 12.5 0.5 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Sporozoite_P67 PF05642.6 ETO28422.1 - 0.26 9.0 6.2 0.41 8.4 4.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Daxx PF03344.10 ETO28422.1 - 1.5 7.1 12.1 2.2 6.6 8.4 1.1 1 0 0 1 1 1 0 Daxx Family DUF3987 PF13148.1 ETO28423.1 - 0.024 13.2 1.7 0.031 12.8 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF1287 PF06940.6 ETO28423.1 - 0.087 12.2 0.7 0.14 11.5 0.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1287) Iso_dh PF00180.15 ETO28425.1 - 2.8e-74 250.1 0.0 5e-74 249.3 0.0 1.3 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1528 PF07515.6 ETO28427.1 - 0.029 14.4 0.4 0.095 12.7 0.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1528) SET PF00856.23 ETO28428.1 - 1.4e-21 77.4 1.6 4.5e-21 75.8 0.4 2.3 2 1 0 2 2 2 1 SET domain DUF4295 PF14128.1 ETO28428.1 - 0.011 15.3 1.3 0.025 14.1 0.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4295) Pex2_Pex12 PF04757.9 ETO28429.1 - 6.2e-23 81.4 0.6 1e-22 80.7 0.4 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.20 ETO28429.1 - 0.0016 18.0 12.7 0.0028 17.2 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO28429.1 - 0.004 17.1 15.7 0.0068 16.4 10.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H PF13771.1 ETO28429.1 - 0.024 14.7 4.0 0.045 13.8 2.8 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_2 PF13639.1 ETO28429.1 - 0.045 13.5 14.3 0.096 12.5 9.9 1.6 1 0 0 1 1 1 0 Ring finger domain zf-Apc11 PF12861.2 ETO28429.1 - 0.16 11.8 6.7 0.24 11.2 3.3 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 ETO28429.1 - 0.18 11.6 11.5 0.56 10.1 8.0 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 ETO28429.1 - 0.33 10.7 11.4 0.58 9.9 7.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-HC5HC2H_2 PF13832.1 ETO28429.1 - 0.34 10.9 7.0 0.2 11.6 3.5 1.7 2 0 0 2 2 2 0 PHD-zinc-finger like domain zf-MIZ PF02891.15 ETO28429.1 - 1.1 8.8 11.7 2.6 7.6 8.1 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DENN PF02141.16 ETO28430.1 - 7.6e-20 71.4 0.4 7.6e-20 71.4 0.3 2.1 2 0 0 2 2 2 1 DENN (AEX-3) domain TPR_16 PF13432.1 ETO28430.1 - 0.17 12.5 0.1 0.49 11.1 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Pkinase PF00069.20 ETO28432.1 - 4.6e-08 32.5 6.1 0.00033 19.8 2.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO28432.1 - 1.4e-05 24.2 7.9 1.9e-05 23.9 2.0 2.7 2 1 0 2 2 2 1 Protein tyrosine kinase DBP10CT PF08147.7 ETO28432.1 - 0.059 13.1 0.3 0.62 9.9 0.1 2.6 2 0 0 2 2 2 0 DBP10CT (NUC160) domain Pkinase_Tyr PF07714.12 ETO28433.1 - 1e-11 44.4 0.5 1.5e-10 40.5 0.3 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 ETO28433.1 - 2.1e-10 40.1 0.1 8e-08 31.7 0.1 2.2 1 1 0 2 2 2 2 Protein kinase domain Viral_Rep PF02407.11 ETO28433.1 - 0.0066 16.4 0.2 0.02 14.8 0.1 1.9 1 1 1 2 2 2 1 Putative viral replication protein GST_N PF02798.15 ETO28434.1 - 6.5e-17 61.4 0.0 1.1e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 ETO28434.1 - 6.7e-05 22.8 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 ETO28434.1 - 0.00011 22.5 0.0 0.00026 21.4 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 ETO28434.1 - 0.013 15.6 0.0 0.032 14.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETO28434.1 - 0.058 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Blt1 PF12754.2 ETO28435.1 - 0.57 9.7 13.3 0.092 12.3 2.2 2.0 1 1 1 2 2 2 0 Cell-cycle control medial ring component BLVR PF06375.6 ETO28436.1 - 0.0051 16.6 4.8 0.0051 16.6 3.3 5.4 3 2 2 5 5 5 2 Bovine leukaemia virus receptor (BLVR) DUF106 PF01956.11 ETO28436.1 - 0.031 13.8 0.0 0.031 13.8 0.0 4.3 1 1 3 4 4 4 0 Integral membrane protein DUF106 DUF1390 PF07150.6 ETO28437.1 - 0.31 10.3 7.4 0.39 10.0 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) SSP160 PF06933.6 ETO28437.1 - 1.1 7.1 10.5 1.3 6.8 7.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DAGK_cat PF00781.19 ETO28438.1 - 3.3e-11 42.7 0.0 1.1e-10 41.0 0.0 1.8 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain G-alpha PF00503.15 ETO28439.1 - 1.5e-37 129.2 16.1 1.5e-37 129.2 11.1 2.0 2 0 0 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.18 ETO28439.1 - 0.00057 19.8 0.2 0.0031 17.4 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.16 ETO28439.1 - 0.0031 16.7 0.4 0.009 15.2 0.1 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO28439.1 - 0.02 14.3 0.4 0.87 8.9 0.3 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 ETO28439.1 - 0.025 13.8 0.1 0.06 12.6 0.1 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B Peptidase_S49_N PF08496.5 ETO28439.1 - 0.045 13.5 12.5 0.87 9.3 4.9 3.5 3 0 0 3 3 3 0 Peptidase family S49 N-terminal ABC_tran PF00005.22 ETO28440.1 - 4.5e-24 85.3 0.0 6.5e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.1 ETO28440.1 - 0.0014 18.9 0.0 0.0021 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 ETO28440.1 - 0.011 15.7 0.2 0.18 11.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 ETO28440.1 - 0.011 15.1 0.1 0.017 14.5 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_29 PF13555.1 ETO28440.1 - 0.029 13.8 0.1 0.063 12.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.1 ETO28440.1 - 0.064 12.3 0.0 0.095 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 ETO28440.1 - 0.086 12.0 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 TrwB_AAD_bind PF10412.4 ETO28440.1 - 0.14 10.7 0.1 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain FliL PF03748.9 ETO28441.1 - 0.00072 19.5 1.1 0.001 19.0 0.1 1.7 2 1 0 2 2 2 1 Flagellar basal body-associated protein FliL Bac_small_YrzI PF09501.5 ETO28441.1 - 0.11 12.3 0.3 0.11 12.3 0.2 2.6 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) BEX PF04538.7 ETO28441.1 - 0.26 11.5 5.4 0.46 10.7 3.8 1.5 1 1 0 1 1 1 0 Brain expressed X-linked like family ABC2_membrane_3 PF12698.2 ETO28442.1 - 2.3e-29 102.4 17.3 4.2e-29 101.6 12.0 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.22 ETO28442.1 - 1e-22 80.8 0.0 1.8e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 ETO28442.1 - 3.5e-11 43.6 2.1 1e-08 35.5 0.1 3.3 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 ETO28442.1 - 0.015 14.5 0.0 0.025 13.8 0.0 1.5 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 ETO28442.1 - 0.024 14.5 0.0 0.14 12.0 0.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit SRP54 PF00448.17 ETO28442.1 - 0.1 12.0 0.2 0.18 11.2 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain WD40 PF00400.27 ETO28443.1 - 1.5e-41 138.8 19.2 5.1e-09 35.6 0.2 5.6 5 1 0 5 5 5 5 WD domain, G-beta repeat Syntaxin-6_N PF09177.6 ETO28444.1 - 1e-13 51.4 0.9 1e-13 51.4 0.6 3.0 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 ETO28444.1 - 5.7e-07 29.1 7.8 1.7e-06 27.6 3.6 2.8 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 ETO28444.1 - 0.00082 19.5 1.2 0.00082 19.5 0.8 3.0 1 1 2 3 3 3 1 Syntaxin DUF2130 PF09903.4 ETO28444.1 - 0.001 17.8 2.1 0.001 17.8 1.4 2.7 1 1 2 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2130) Reo_sigmaC PF04582.7 ETO28444.1 - 0.0059 15.8 7.8 0.11 11.6 0.8 2.1 1 1 1 2 2 2 2 Reovirus sigma C capsid protein Use1 PF09753.4 ETO28444.1 - 0.011 15.1 15.8 0.016 14.6 11.0 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 UPF0184 PF03670.8 ETO28444.1 - 0.013 15.6 0.9 0.013 15.6 0.6 2.9 1 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) DUF2937 PF11157.3 ETO28444.1 - 0.014 14.6 0.5 0.014 14.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Laminin_II PF06009.7 ETO28444.1 - 0.031 14.0 15.3 0.49 10.1 1.8 3.3 1 1 3 4 4 4 0 Laminin Domain II Bromo_TP PF07524.8 ETO28444.1 - 0.058 13.1 0.2 4.8 6.9 0.0 3.0 3 0 0 3 3 2 0 Bromodomain associated KxDL PF10241.4 ETO28444.1 - 0.065 13.1 0.4 0.065 13.1 0.3 3.5 1 1 1 3 3 3 0 Uncharacterized conserved protein Fusion_gly PF00523.13 ETO28444.1 - 0.1 10.6 7.1 0.088 10.8 1.8 2.4 2 1 0 2 2 2 0 Fusion glycoprotein F0 Utp12 PF04003.7 ETO28444.1 - 0.11 12.4 2.5 3.3 7.6 0.0 2.8 2 1 0 2 2 2 0 Dip2/Utp12 Family APG6 PF04111.7 ETO28444.1 - 0.12 11.3 21.2 0.057 12.4 7.2 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF2959 PF11172.3 ETO28444.1 - 0.14 11.8 11.8 0.26 11.0 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2959) Tape_meas_lam_C PF09718.5 ETO28444.1 - 0.16 11.9 1.3 0.52 10.2 0.9 1.9 1 1 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF2513 PF10711.4 ETO28444.1 - 0.31 11.1 4.5 0.099 12.7 1.0 1.9 2 1 0 2 2 2 0 Hypothetical protein (DUF2513) AAA_13 PF13166.1 ETO28444.1 - 0.34 9.2 18.2 0.53 8.6 12.6 1.3 1 1 0 1 1 1 0 AAA domain DUF106 PF01956.11 ETO28444.1 - 0.36 10.3 3.4 2.4 7.6 2.3 2.1 1 1 0 1 1 1 0 Integral membrane protein DUF106 DUF2203 PF09969.4 ETO28444.1 - 0.57 10.4 11.5 3.7 7.8 0.4 3.0 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) ALMT PF11744.3 ETO28444.1 - 0.76 8.3 12.3 4 5.9 8.4 2.0 1 1 0 1 1 1 0 Aluminium activated malate transporter GvpL_GvpF PF06386.6 ETO28444.1 - 0.85 9.1 10.0 2.1 7.8 6.3 2.0 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF2408 PF10303.4 ETO28444.1 - 0.96 9.5 15.6 4.6 7.3 4.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) DUF342 PF03961.8 ETO28444.1 - 0.98 7.7 16.3 0.73 8.1 2.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF342) HalX PF08663.5 ETO28444.1 - 1.1 9.3 6.2 7.3 6.6 0.0 3.2 3 1 1 4 4 3 0 HalX domain Fib_alpha PF08702.5 ETO28444.1 - 1.4 9.0 21.2 0.6 10.2 2.4 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family GrpE PF01025.14 ETO28444.1 - 1.5 8.3 13.5 8.5 5.8 7.1 2.7 1 1 1 2 2 2 0 GrpE BLOC1_2 PF10046.4 ETO28444.1 - 2.4 8.3 18.0 0.53 10.4 2.3 3.4 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GLE1 PF07817.8 ETO28444.1 - 3.4 6.5 14.5 3.4 6.5 1.4 2.4 2 1 0 2 2 2 0 GLE1-like protein DUF4407 PF14362.1 ETO28444.1 - 4.2 6.2 14.7 32 3.3 8.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF883 PF05957.8 ETO28444.1 - 4.4 7.7 11.5 1.6 9.1 0.1 3.6 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF883) HSCB_C PF07743.8 ETO28444.1 - 4.4 7.8 11.9 0.95 9.9 0.4 3.7 1 1 1 2 2 1 0 HSCB C-terminal oligomerisation domain WXG100 PF06013.7 ETO28444.1 - 6.1 6.9 14.5 1.3 9.1 0.1 4.6 3 2 1 4 4 4 0 Proteins of 100 residues with WXG TLD PF07534.11 ETO28445.1 - 2.9e-30 105.0 1.2 3.5e-30 104.8 0.1 1.7 2 0 0 2 2 2 1 TLD KxDL PF10241.4 ETO28445.1 - 0.33 10.8 7.2 0.26 11.2 3.4 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein Prismane PF03063.15 ETO28446.1 - 1.6e-55 188.5 0.0 1.7e-55 188.3 0.0 1.0 1 0 0 1 1 1 1 Prismane/CO dehydrogenase family Prismane PF03063.15 ETO28447.1 - 7.9e-47 159.7 0.0 3.4e-32 111.5 0.0 2.1 2 0 0 2 2 2 2 Prismane/CO dehydrogenase family Smoothelin PF12510.3 ETO28447.1 - 0.13 12.1 0.1 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Smoothelin cytoskeleton protein Exo_endo_phos PF03372.18 ETO28448.1 - 0.045 13.6 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family TLD PF07534.11 ETO28449.1 - 1e-10 41.7 1.8 1.8e-10 40.9 1.2 1.3 1 0 0 1 1 1 1 TLD SDA1 PF05285.7 ETO28449.1 - 0.00021 20.7 41.9 0.00034 20.0 29.0 1.2 1 0 0 1 1 1 1 SDA1 Daxx PF03344.10 ETO28449.1 - 0.0027 16.2 28.2 0.0034 15.9 19.6 1.1 1 0 0 1 1 1 1 Daxx Family fn3 PF00041.16 ETO28449.1 - 0.0092 16.0 0.0 0.094 12.8 0.0 2.5 2 0 0 2 2 2 1 Fibronectin type III domain Nop14 PF04147.7 ETO28449.1 - 0.079 10.8 39.5 0.13 10.1 27.4 1.3 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.8 ETO28449.1 - 1 8.8 37.2 1.8 8.1 25.8 1.5 1 0 0 1 1 1 0 YL1 nuclear protein DUF2146 PF10220.4 ETO28449.1 - 2.1 6.2 11.7 2.3 6.0 8.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) CDC27 PF09507.5 ETO28449.1 - 5.1 6.2 40.0 7.8 5.6 27.8 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF1183 PF06682.7 ETO28450.1 - 0.00073 19.2 2.8 0.0014 18.2 2.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) TMEM154 PF15102.1 ETO28450.1 - 0.00092 18.9 5.8 0.00092 18.9 4.0 3.3 3 2 1 4 4 4 1 TMEM154 protein family Viral_Beta_CD PF04530.7 ETO28450.1 - 0.0012 18.9 1.0 0.0033 17.5 0.7 1.7 1 0 0 1 1 1 1 Viral Beta C/D like family EMP24_GP25L PF01105.19 ETO28450.1 - 0.0076 15.9 1.8 0.016 14.9 1.3 1.6 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2615 PF11027.3 ETO28450.1 - 0.0083 16.0 2.4 0.0083 16.0 1.7 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF2615) Plant_vir_prot PF01307.12 ETO28450.1 - 0.019 14.6 1.7 0.054 13.2 1.2 1.7 1 0 0 1 1 1 0 Plant viral movement protein EphA2_TM PF14575.1 ETO28450.1 - 0.047 14.0 4.7 0.21 12.0 0.1 3.2 2 1 1 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 ETO28450.1 - 0.057 13.6 0.0 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator OppC_N PF12911.2 ETO28450.1 - 0.089 12.1 0.4 0.089 12.1 0.3 2.1 2 0 0 2 2 1 0 N-terminal TM domain of oligopeptide transport permease C Serinc PF03348.10 ETO28450.1 - 0.11 11.2 7.2 0.21 10.2 5.0 1.5 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF1510 PF07423.6 ETO28450.1 - 0.12 11.7 19.9 0.048 13.0 6.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1510) Tetraspannin PF00335.15 ETO28450.1 - 0.16 11.2 0.1 0.16 11.2 0.1 2.3 1 1 1 2 2 2 0 Tetraspanin family DUF4064 PF13273.1 ETO28450.1 - 0.17 12.0 7.3 0.096 12.7 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) OSTbeta PF15048.1 ETO28450.1 - 0.65 10.0 4.6 1.4 8.9 3.2 1.6 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein ETRAMP PF09716.5 ETO28450.1 - 0.68 9.9 10.5 0.26 11.2 1.4 2.5 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF3357 PF11837.3 ETO28450.1 - 0.69 9.7 4.5 3.1 7.6 2.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) SID-1_RNA_chan PF13965.1 ETO28450.1 - 4.8 5.2 15.2 1.6 6.7 7.3 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 EpsG PF14897.1 ETO28450.1 - 4.9 5.9 21.0 0.12 11.2 5.3 2.2 2 0 0 2 2 2 0 EpsG family PAH PF02671.16 ETO28451.1 - 0.0026 17.3 0.6 0.38 10.3 0.0 2.4 2 0 0 2 2 2 2 Paired amphipathic helix repeat Zip PF02535.17 ETO28451.1 - 0.0054 15.7 0.7 0.009 15.0 0.5 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter Neur_chan_memb PF02932.11 ETO28452.1 - 0.00049 20.0 2.9 0.00049 20.0 2.0 1.8 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Kinesin-relat_1 PF12711.2 ETO28452.1 - 0.14 12.5 4.5 0.91 9.9 0.2 2.6 2 0 0 2 2 2 0 Kinesin motor ABC2_membrane_3 PF12698.2 ETO28452.1 - 0.44 9.5 2.0 0.52 9.2 1.4 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF722 PF05263.6 ETO28452.1 - 5.3 7.1 8.5 2.4 8.2 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF722) Pkinase PF00069.20 ETO28453.1 - 2.9e-24 85.6 0.1 2.9e-24 85.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO28453.1 - 4.5e-16 58.7 0.1 6.6e-16 58.1 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LigA PF07746.6 ETO28453.1 - 0.073 13.0 0.1 0.17 11.9 0.0 1.6 2 0 0 2 2 2 0 Aromatic-ring-opening dioxygenase LigAB, LigA subunit DNA_ligase_A_C PF04679.10 ETO28454.1 - 0.033 14.5 0.0 0.039 14.3 0.0 1.2 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region TatC PF00902.13 ETO28454.1 - 0.036 13.4 0.1 0.043 13.2 0.1 1.1 1 0 0 1 1 1 0 Sec-independent protein translocase protein (TatC) EamA PF00892.15 ETO28454.1 - 0.14 12.1 3.1 4.6 7.3 0.4 2.1 1 1 1 2 2 2 0 EamA-like transporter family Daxx PF03344.10 ETO28455.1 - 0.061 11.8 31.0 0.084 11.3 21.5 1.1 1 0 0 1 1 1 0 Daxx Family Caa3_CtaG PF09678.5 ETO28455.1 - 0.061 12.2 1.3 0.089 11.7 0.9 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) Utp14 PF04615.8 ETO28455.1 - 0.23 9.6 35.2 0.29 9.2 24.4 1.1 1 0 0 1 1 1 0 Utp14 protein DUF605 PF04652.11 ETO28455.1 - 0.32 10.3 25.1 0.45 9.8 17.4 1.2 1 0 0 1 1 1 0 Vta1 like Dapper PF15268.1 ETO28455.1 - 3.3 6.4 13.0 4.1 6.0 9.0 1.2 1 0 0 1 1 1 0 Dapper Hid1 PF12722.2 ETO28455.1 - 6.4 4.3 37.1 10 3.6 25.7 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nop14 PF04147.7 ETO28455.1 - 8.8 4.0 36.1 13 3.5 25.1 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2481 PF10654.4 ETO28456.1 - 0.032 13.9 0.3 0.068 12.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2481) MFS_Mycoplasma PF07672.8 ETO28456.1 - 0.087 11.9 3.5 0.06 12.5 1.3 1.5 1 1 0 1 1 1 0 Mycoplasma MFS transporter Pex14_N PF04695.8 ETO28456.1 - 0.18 11.8 3.5 0.31 11.0 2.4 1.7 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region T2SF PF00482.18 ETO28456.1 - 0.4 10.6 4.8 15 5.4 2.3 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F HCV_NS5a_C PF12941.2 ETO28456.1 - 0.57 9.7 4.6 0.79 9.2 0.7 2.1 2 0 0 2 2 2 0 HCV NS5a protein C-terminal region EphA2_TM PF14575.1 ETO28456.1 - 3.7 8.0 7.5 0.48 10.8 0.3 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF106 PF01956.11 ETO28456.1 - 8 5.9 15.5 0.15 11.5 1.3 2.3 1 1 1 2 2 2 0 Integral membrane protein DUF106 DUF1777 PF08648.7 ETO28457.1 - 0.0067 16.1 22.8 0.0067 16.1 15.8 5.8 2 1 4 6 6 6 2 Protein of unknown function (DUF1777) YqhR PF11085.3 ETO28458.1 - 0.69 9.4 10.6 0.75 9.3 7.3 1.0 1 0 0 1 1 1 0 Conserved membrane protein YqhR NKAIN PF05640.9 ETO28458.1 - 2.9 6.8 8.8 0.97 8.3 3.9 1.7 1 1 1 2 2 2 0 Na,K-Atpase Interacting protein NAGLU_N PF12971.2 ETO28459.1 - 5.6e-09 35.5 0.2 4.2e-08 32.7 0.0 2.1 1 1 1 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Peptidase_M56 PF05569.6 ETO28459.1 - 0.011 14.7 0.2 0.015 14.3 0.1 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 Ion_trans PF00520.26 ETO28459.1 - 0.051 12.8 0.8 0.18 11.0 0.1 1.9 2 0 0 2 2 2 0 Ion transport protein WD40 PF00400.27 ETO28460.1 - 1.3e-12 47.0 0.3 1.2e-07 31.3 0.0 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 ETO28460.1 - 0.0051 16.5 0.4 0.36 10.6 0.1 2.7 2 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region HTH_43 PF09904.4 ETO28460.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix RNase_H2-Ydr279 PF09468.5 ETO28461.1 - 0.53 9.4 10.5 0.7 9.0 7.3 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Gmx_para_CXXCG PF09535.5 ETO28462.1 - 0.072 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (Gmx_para_CXXCG) DUF2265 PF10023.4 ETO28462.1 - 0.16 11.0 3.1 3 6.8 0.0 2.1 1 1 1 2 2 2 0 Predicted aminopeptidase (DUF2265) DUF912 PF06024.7 ETO28462.1 - 0.74 9.9 0.0 0.74 9.9 0.0 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CobT PF06213.7 ETO28462.1 - 1.5 7.9 11.1 2.2 7.3 7.7 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RRN3 PF05327.6 ETO28462.1 - 3.1 5.7 7.1 4.7 5.1 4.9 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PBP_sp32 PF07222.7 ETO28462.1 - 3.2 6.8 9.4 5.4 6.1 6.5 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 alpha-hel2 PF14456.1 ETO28463.1 - 0.011 14.4 4.4 0.014 14.1 3.1 1.1 1 0 0 1 1 1 0 Alpha-helical domain 2 Upf2 PF04050.9 ETO28463.1 - 0.087 12.5 18.7 0.12 12.0 13.0 1.2 1 0 0 1 1 1 0 Up-frameshift suppressor 2 Bd3614-deam PF14439.1 ETO28463.1 - 0.24 11.2 2.8 0.37 10.6 1.9 1.2 1 0 0 1 1 1 0 Bd3614-like deaminase PRCC PF10253.4 ETO28463.1 - 0.26 11.9 12.0 0.37 11.4 8.3 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Daxx PF03344.10 ETO28463.1 - 0.33 9.3 16.3 0.36 9.2 11.3 1.0 1 0 0 1 1 1 0 Daxx Family RNase_H2_suC PF08615.6 ETO28463.1 - 4.3 7.1 6.7 7.9 6.3 4.7 1.4 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF506 PF04720.7 ETO28463.1 - 8.9 5.8 14.8 14 5.2 10.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF506) Atg14 PF10186.4 ETO28463.1 - 9.3 5.0 17.5 12 4.7 12.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Peptidase_M13 PF01431.16 ETO28464.1 - 0.0026 16.9 0.0 0.0042 16.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 WLM PF08325.5 ETO28464.1 - 0.014 15.3 0.0 0.042 13.7 0.0 1.8 1 0 0 1 1 1 0 WLM domain DUF4344 PF14247.1 ETO28464.1 - 0.11 12.1 0.1 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4344) Peptidase_M50B PF13398.1 ETO28464.1 - 0.17 11.2 0.2 0.24 10.7 0.2 1.3 1 0 0 1 1 1 0 Peptidase M50B-like zf-C3HC4 PF00097.20 ETO28465.1 - 0.00026 20.5 6.1 0.00078 19.0 4.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO28465.1 - 0.00051 19.8 5.9 0.00051 19.8 4.1 2.5 3 0 0 3 3 3 1 Ring finger domain zf-HC5HC2H PF13771.1 ETO28465.1 - 0.015 15.3 1.0 0.04 14.0 0.1 2.1 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-rbx1 PF12678.2 ETO28465.1 - 0.029 14.4 2.8 0.029 14.4 2.0 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger AA_permease PF00324.16 ETO28465.1 - 0.039 12.2 0.7 0.057 11.7 0.5 1.2 1 0 0 1 1 1 0 Amino acid permease zf-HC5HC2H_2 PF13832.1 ETO28465.1 - 3.3 7.7 8.0 0.52 10.3 0.4 2.8 3 0 0 3 3 3 0 PHD-zinc-finger like domain Vps51 PF08700.6 ETO28468.1 - 0.067 13.0 0.4 0.2 11.5 0.4 1.6 2 0 0 2 2 2 0 Vps51/Vps67 DUF4159 PF13709.1 ETO28468.1 - 0.13 11.3 0.0 0.27 10.3 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4159) Vac14_Fig4_bd PF11916.3 ETO28469.1 - 2.7e-35 121.1 3.1 4.2e-35 120.5 2.1 1.3 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding FISNA PF14484.1 ETO28469.1 - 0.01 15.7 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 0 Fish-specific NACHT associated domain DUF1396 PF07161.8 ETO28470.1 - 0.066 12.8 2.6 0.3 10.7 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1396) Bactofilin PF04519.8 ETO28470.1 - 0.066 13.2 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Polymer-forming cytoskeletal DUF2360 PF10152.4 ETO28471.1 - 1.9e-05 24.9 6.2 0.00013 22.3 4.3 1.9 1 1 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) DUF948 PF06103.6 ETO28471.1 - 0.0034 17.2 1.7 0.0055 16.5 0.2 2.0 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF948) DivIC PF04977.10 ETO28471.1 - 0.016 14.6 0.8 0.032 13.7 0.6 1.4 1 0 0 1 1 1 0 Septum formation initiator Kinetocho_Slk19 PF12709.2 ETO28471.1 - 0.025 14.6 0.6 0.052 13.6 0.4 1.5 1 0 0 1 1 1 0 Central kinetochore-associated Med9 PF07544.8 ETO28471.1 - 0.036 13.7 1.5 0.1 12.3 1.1 1.8 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 bZIP_1 PF00170.16 ETO28471.1 - 0.06 13.3 1.2 0.1 12.5 0.8 1.3 1 0 0 1 1 1 0 bZIP transcription factor Ribosomal_60s PF00428.14 ETO28471.1 - 0.062 13.7 1.8 12 6.3 1.1 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF3450 PF11932.3 ETO28471.1 - 0.39 9.9 2.3 0.4 9.9 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Pex14_N PF04695.8 ETO28471.1 - 1.1 9.3 5.5 2.1 8.4 0.6 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Dmrt1 PF12374.3 ETO28471.1 - 6.6 7.1 15.4 0.21 11.9 5.1 2.2 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 Kinesin PF00225.18 ETO28472.1 - 1.6e-25 89.5 0.0 1.6e-25 89.5 0.0 6.4 3 2 1 5 5 5 1 Kinesin motor domain PsbQ PF05757.6 ETO28473.1 - 0.017 14.5 0.4 0.028 13.8 0.3 1.3 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) PDZ_2 PF13180.1 ETO28474.1 - 3.5e-07 30.0 0.0 8.8e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 ETO28474.1 - 0.0037 17.4 0.0 0.0072 16.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) DUF2859 PF11072.3 ETO28474.1 - 0.024 14.0 0.2 0.13 11.7 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2859) Secretin_N_2 PF07655.8 ETO28474.1 - 0.21 11.9 10.2 0.41 11.0 7.1 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain DUF912 PF06024.7 ETO28474.1 - 4 7.5 6.6 7.3 6.7 4.6 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PARP PF00644.15 ETO28476.1 - 1.6e-07 30.9 2.2 4.7e-07 29.4 1.1 2.0 1 1 1 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain TF_Zn_Ribbon PF08271.7 ETO28476.1 - 0.0012 18.1 3.4 0.0033 16.7 2.4 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding IBR PF01485.16 ETO28476.1 - 0.1 12.4 12.7 0.065 13.1 7.1 1.9 2 0 0 2 2 2 0 IBR domain Whib PF02467.11 ETO28476.1 - 0.16 12.2 0.8 0.35 11.2 0.6 1.6 1 0 0 1 1 1 0 Transcription factor WhiB TRAM_LAG1_CLN8 PF03798.11 ETO28477.1 - 8.3e-24 84.2 29.0 8.3e-24 84.2 20.1 1.4 2 0 0 2 2 2 1 TLC domain Syntaxin_2 PF14523.1 ETO28478.1 - 0.0012 18.7 6.9 0.0012 18.7 4.8 1.9 2 1 0 2 2 2 1 Syntaxin-like protein Hemagglutinin PF00509.13 ETO28478.1 - 0.0072 14.5 4.6 0.0097 14.0 3.2 1.1 1 0 0 1 1 1 1 Haemagglutinin Herpes_UL36 PF03586.8 ETO28478.1 - 0.016 14.3 0.1 0.023 13.8 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein Syntaxin-6_N PF09177.6 ETO28478.1 - 0.07 13.5 3.3 0.21 12.0 2.3 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal PspB PF06667.7 ETO28478.1 - 0.093 12.6 1.5 0.67 9.9 1.0 2.3 1 1 0 1 1 1 0 Phage shock protein B FliD_N PF02465.13 ETO28478.1 - 0.14 12.5 7.2 0.75 10.1 5.0 2.3 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus GAS PF13851.1 ETO28478.1 - 0.26 10.4 20.0 0.015 14.4 7.0 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DivIC PF04977.10 ETO28478.1 - 0.71 9.4 8.1 0.23 10.9 2.8 2.4 1 1 1 2 2 2 0 Septum formation initiator TMF_TATA_bd PF12325.3 ETO28478.1 - 0.93 9.2 17.5 0.36 10.5 6.7 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Prefoldin_3 PF13758.1 ETO28478.1 - 1.1 9.1 8.5 0.69 9.7 1.1 2.5 1 1 1 2 2 2 0 Prefoldin subunit TIR PF01582.15 ETO28478.1 - 1.1 8.7 6.1 0.29 10.5 1.4 2.0 2 0 0 2 2 2 0 TIR domain DUF4407 PF14362.1 ETO28478.1 - 2.2 7.1 9.9 2.9 6.7 6.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF972 PF06156.8 ETO28478.1 - 4.6 7.6 12.5 0.21 11.9 2.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) AAA_23 PF13476.1 ETO28478.1 - 4.8 7.4 15.3 8.2 6.6 10.6 1.3 1 0 0 1 1 1 0 AAA domain P4Ha_N PF08336.6 ETO28478.1 - 4.8 6.9 11.7 0.15 11.8 3.3 2.1 2 2 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Ly49 PF08391.5 ETO28478.1 - 4.9 7.2 13.9 0.06 13.4 2.0 2.4 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region RecX PF02631.11 ETO28478.1 - 5.1 7.3 10.4 0.5 10.5 3.9 1.8 2 0 0 2 2 2 0 RecX family APG6 PF04111.7 ETO28478.1 - 6.7 5.6 17.6 7.8 5.4 11.3 1.6 1 1 0 1 1 1 0 Autophagy protein Apg6 Spc24 PF08286.6 ETO28478.1 - 7.5 6.2 14.7 0.066 12.9 2.4 2.5 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 DUF342 PF03961.8 ETO28478.1 - 9.2 4.5 11.8 15 3.8 8.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Put_Phosphatase PF06888.7 ETO28479.1 - 0.045 12.8 0.0 0.088 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative Phosphatase T3SS_LEE_assoc PF13327.1 ETO28479.1 - 0.055 13.0 1.1 0.081 12.5 0.1 1.7 2 0 0 2 2 2 0 Type III secretion system subunit ODV-E18 PF10717.4 ETO28479.1 - 0.097 12.1 2.9 0.18 11.2 2.0 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Chordopox_A13L PF05961.6 ETO28479.1 - 5.9 6.9 8.1 12 5.8 5.2 1.8 1 1 0 1 1 1 0 Chordopoxvirus A13L protein Peptidase_S9 PF00326.16 ETO28481.1 - 0.00016 20.9 0.6 0.014 14.6 0.0 3.4 3 1 1 4 4 4 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETO28481.1 - 0.0011 18.7 0.0 0.68 9.6 0.0 2.3 2 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 ETO28481.1 - 0.012 15.0 0.1 0.027 13.9 0.1 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PIN_4 PF13638.1 ETO28481.1 - 0.65 10.0 8.5 0.55 10.3 0.6 2.5 3 0 0 3 3 3 0 PIN domain DUF702 PF05142.7 ETO28481.1 - 2.6 8.1 11.6 0.074 13.2 1.6 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF702) DUF2361 PF10153.4 ETO28481.1 - 8.4 6.6 14.6 0.48 10.6 0.4 2.9 2 1 1 3 3 3 0 Uncharacterised conserved protein (DUF2361) AhpC-TSA PF00578.16 ETO28482.1 - 4.8e-10 39.2 0.3 2.2e-09 37.0 0.1 2.1 1 1 0 2 2 2 1 AhpC/TSA family DUF3199 PF11436.3 ETO28482.1 - 0.0015 18.4 0.2 0.0032 17.3 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3199) PH_5 PF15405.1 ETO28483.1 - 0.0057 16.5 0.2 0.0067 16.3 0.2 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain NRDD PF13597.1 ETO28483.1 - 0.014 13.5 0.2 0.015 13.3 0.2 1.0 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase Copine PF07002.11 ETO28483.1 - 0.048 13.3 0.0 8.8 6.0 0.0 2.1 1 1 1 2 2 2 0 Copine Sec15 PF04091.7 ETO28484.1 - 2.1e-30 106.1 5.8 7.7e-23 81.2 1.3 2.8 2 1 0 2 2 2 2 Exocyst complex subunit Sec15-like LRR_4 PF12799.2 ETO28484.1 - 0.013 15.0 0.2 0.036 13.6 0.1 1.7 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) DUF1404 PF07185.6 ETO28484.1 - 0.033 13.7 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1404) CTC1_2 PF15491.1 ETO28484.1 - 0.063 12.2 0.0 0.095 11.6 0.0 1.2 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 Vps51 PF08700.6 ETO28486.1 - 5.7e-07 29.2 3.7 5.7e-07 29.2 2.5 2.5 2 0 0 2 2 2 1 Vps51/Vps67 COG5 PF10392.4 ETO28486.1 - 0.097 12.6 9.4 0.11 12.4 2.3 2.9 2 1 0 2 2 2 0 Golgi transport complex subunit 5 DUF2203 PF09969.4 ETO28486.1 - 8.2 6.6 11.2 1.8 8.8 3.2 2.7 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Acyl-CoA_dh_C PF12806.2 ETO28487.1 - 0.083 12.7 1.6 0.21 11.4 1.1 1.6 1 0 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like MCM_N PF14551.1 ETO28489.1 - 0.069 13.6 2.0 0.09 13.2 0.0 2.2 3 0 0 3 3 3 0 MCM N-terminal domain TPR_12 PF13424.1 ETO28493.1 - 0.00015 21.6 4.0 0.11 12.4 0.2 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat PH_5 PF15405.1 ETO28493.1 - 0.0018 18.2 0.3 0.0036 17.2 0.2 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Clathrin PF00637.15 ETO28493.1 - 0.005 16.4 3.5 0.38 10.3 0.1 3.6 1 1 2 3 3 3 1 Region in Clathrin and VPS TPR_11 PF13414.1 ETO28493.1 - 0.0065 16.0 6.7 1.3 8.7 0.1 3.8 3 0 0 3 3 3 2 TPR repeat TPR_7 PF13176.1 ETO28493.1 - 0.017 14.8 4.2 9.5 6.2 0.2 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETO28493.1 - 1.2 9.0 11.6 16 5.5 0.9 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 ETO28493.1 - 1.8 8.7 15.9 7.7 6.7 0.1 4.9 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 ETO28493.1 - 5 6.9 11.2 2.2 8.0 0.6 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.27 ETO28494.1 - 2.5e-13 49.3 1.5 0.85 9.6 0.0 7.8 8 0 0 8 8 8 4 WD domain, G-beta repeat IKI3 PF04762.7 ETO28494.1 - 1.2e-08 33.3 5.6 4.9e-07 28.0 0.2 3.4 3 1 0 3 3 3 2 IKI3 family DUF3312 PF11768.3 ETO28494.1 - 0.0092 14.2 3.7 0.14 10.3 0.0 3.3 3 1 1 4 4 4 2 Protein of unknown function (DUF3312) DUF2201_N PF13203.1 ETO28495.1 - 0.026 13.6 0.3 0.028 13.5 0.2 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain FLO_LFY PF01698.11 ETO28495.1 - 0.057 12.2 3.3 0.071 11.9 2.3 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Menin PF05053.8 ETO28495.1 - 0.35 8.9 11.5 0.42 8.7 8.0 1.2 1 0 0 1 1 1 0 Menin TMEM151 PF14857.1 ETO28495.1 - 1.4 7.3 5.4 1.8 7.0 3.8 1.1 1 0 0 1 1 1 0 TMEM151 family SAM_1 PF00536.25 ETO28497.1 - 0.013 15.6 0.4 0.035 14.2 0.3 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Tad PF13400.1 ETO28498.1 - 0.19 11.7 0.3 0.66 10.0 0.0 2.1 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like Zip PF02535.17 ETO28499.1 - 8.4e-05 21.7 0.1 0.00014 21.0 0.0 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter DUF1510 PF07423.6 ETO28499.1 - 0.074 12.4 16.3 0.92 8.8 11.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4179 PF13786.1 ETO28499.1 - 0.11 12.7 3.9 0.41 10.8 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) Chordopox_A33R PF05966.7 ETO28499.1 - 0.16 10.6 3.9 0.18 10.5 0.9 2.2 2 0 0 2 2 2 0 Chordopoxvirus A33R protein Neur_chan_memb PF02932.11 ETO28499.1 - 0.21 11.4 2.4 0.2 11.5 0.7 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.9 ETO28499.1 - 0.41 10.3 7.9 0.59 9.8 5.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4551 PF15087.1 ETO28499.1 - 0.65 8.2 6.6 0.92 7.7 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ly49 PF08391.5 ETO28499.1 - 1.3 9.1 6.2 3.8 7.6 3.2 2.3 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region PH PF00169.24 ETO28500.1 - 0.00014 22.0 2.6 0.0002 21.5 1.7 1.6 1 1 0 1 1 1 1 PH domain Polyoma_coat2 PF00761.15 ETO28500.1 - 1.6 8.1 5.8 4.8 6.5 1.4 2.1 2 0 0 2 2 2 0 Polyomavirus coat protein AAA_23 PF13476.1 ETO28500.1 - 2.4 8.4 13.0 3.4 7.9 9.0 1.2 1 0 0 1 1 1 0 AAA domain UDPGP PF01704.13 ETO28501.1 - 5.9e-06 25.0 0.0 7.7e-06 24.6 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Daxx PF03344.10 ETO28503.1 - 0.012 14.1 39.4 0.014 13.9 27.3 1.1 1 0 0 1 1 1 0 Daxx Family Borrelia_P83 PF05262.6 ETO28503.1 - 0.12 10.5 43.9 0.15 10.3 30.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein MIP-T3 PF10243.4 ETO28503.1 - 0.24 9.8 71.3 0.28 9.5 49.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 GPAT_N PF14829.1 ETO28504.1 - 0.049 13.3 0.2 0.12 12.0 0.1 1.8 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal Vps39_2 PF10367.4 ETO28504.1 - 1.9 8.7 10.2 9.4 6.4 0.1 2.4 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 DUF4339 PF14237.1 ETO28505.1 - 0.00065 19.2 0.1 0.0017 17.8 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4339) Clp1 PF06807.9 ETO28506.1 - 1.8e-18 67.0 0.4 5.7e-16 58.8 0.5 2.9 2 1 0 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 ETO28506.1 - 0.019 14.6 0.0 0.044 13.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 ETO28506.1 - 0.026 14.3 0.0 0.17 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 ETO28506.1 - 0.04 13.3 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_17 PF13207.1 ETO28506.1 - 0.15 12.8 0.2 1.9 9.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain zf-RING_2 PF13639.1 ETO28507.1 - 9.3e-06 25.3 6.2 1.9e-05 24.4 4.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 ETO28507.1 - 5.1e-05 23.3 3.3 0.00017 21.6 2.3 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 ETO28507.1 - 0.0015 18.1 7.9 0.0031 17.1 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) KSR1-SAM PF13543.1 ETO28507.1 - 0.0051 16.6 0.1 0.0051 16.6 0.1 2.1 2 0 0 2 2 2 1 SAM like domain present in kinase suppressor RAS 1 zf-Apc11 PF12861.2 ETO28507.1 - 0.043 13.6 3.5 0.11 12.3 2.4 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Asp-B-Hydro_N PF05279.6 ETO28507.1 - 0.11 12.3 8.7 0.15 11.8 6.0 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region RINGv PF12906.2 ETO28507.1 - 0.25 11.4 10.3 0.089 12.8 5.0 1.9 2 0 0 2 2 2 0 RING-variant domain zf-C3HC4_2 PF13923.1 ETO28507.1 - 1.8 8.6 7.9 4.5 7.3 5.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NESP55 PF06390.7 ETO28508.1 - 0.0097 15.3 13.2 0.013 14.8 9.2 1.2 1 0 0 1 1 1 1 Neuroendocrine-specific golgi protein P55 (NESP55) Trypan_PARP PF05887.6 ETO28508.1 - 0.69 9.7 14.7 0.96 9.2 10.2 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Daxx PF03344.10 ETO28508.1 - 5.3 5.4 21.0 6 5.2 14.5 1.0 1 0 0 1 1 1 0 Daxx Family FGF-BP1 PF06473.7 ETO28508.1 - 6.6 6.2 7.5 6.5 6.2 5.2 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Ctr PF04145.10 ETO28509.1 - 0.0028 17.7 0.1 0.0028 17.7 0.0 1.9 2 0 0 2 2 2 1 Ctr copper transporter family Shisa PF13908.1 ETO28509.1 - 0.017 15.3 0.3 0.023 14.8 0.2 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF2956 PF11169.3 ETO28509.1 - 0.046 13.6 0.1 0.046 13.6 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2956) DUF1510 PF07423.6 ETO28509.1 - 0.12 11.7 0.0 0.12 11.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) PIG-P PF08510.7 ETO28509.1 - 0.17 11.5 0.6 0.26 10.9 0.0 1.7 2 0 0 2 2 2 0 PIG-P DUF912 PF06024.7 ETO28509.1 - 0.22 11.5 0.0 0.22 11.5 0.0 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Mem_trans PF03547.13 ETO28509.1 - 0.67 8.1 2.7 0.32 9.2 0.4 1.4 1 1 1 2 2 2 0 Membrane transport protein FGF-BP1 PF06473.7 ETO28509.1 - 2.8 7.4 11.6 1.3 8.6 0.1 2.1 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) ORC6 PF05460.8 ETO28509.1 - 8.3 5.4 13.6 13 4.7 9.3 1.4 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) MIP-T3 PF10243.4 ETO28509.1 - 10 4.4 20.8 20 3.5 14.4 1.4 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 MIP-T3 PF10243.4 ETO28510.1 - 1.4e-05 23.7 11.1 1.7e-05 23.5 7.7 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Neur_chan_memb PF02932.11 ETO28510.1 - 0.00067 19.6 6.3 0.00067 19.6 4.4 1.7 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region DUF1700 PF08006.6 ETO28510.1 - 0.032 13.5 0.2 0.044 13.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) RR_TM4-6 PF06459.7 ETO28510.1 - 0.72 9.6 13.6 0.036 13.9 5.4 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Folate_carrier PF01770.13 ETO28510.1 - 0.81 8.1 6.4 1.7 7.0 4.5 1.6 1 1 0 1 1 1 0 Reduced folate carrier Raftlin PF15250.1 ETO28510.1 - 2.9 6.3 15.5 0.08 11.4 6.5 1.4 2 0 0 2 2 2 0 Raftlin Pox_Ag35 PF03286.9 ETO28510.1 - 4.7 6.6 22.6 0.013 14.9 7.7 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF4337 PF14235.1 ETO28510.1 - 5.8 6.7 7.0 1.6 8.5 2.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Ctr PF04145.10 ETO28510.1 - 7.4 6.6 7.8 10 6.1 4.3 2.1 1 1 1 2 2 2 0 Ctr copper transporter family SID-1_RNA_chan PF13965.1 ETO28510.1 - 7.7 4.5 20.0 0.0087 14.2 3.4 2.0 1 1 1 2 2 2 0 dsRNA-gated channel SID-1 Pkinase PF00069.20 ETO28511.1 - 7.2e-13 48.2 0.0 1.1e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF2981 PF11200.3 ETO28511.1 - 0.04 12.9 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Ank_4 PF13637.1 ETO28512.1 - 7.5e-15 54.9 0.2 3e-06 27.5 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO28512.1 - 1.7e-14 53.9 0.1 1.4e-13 50.9 0.1 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO28512.1 - 6.5e-13 48.4 0.0 2.7e-07 30.6 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 ETO28512.1 - 6.6e-13 47.7 3.0 2.4e-07 30.1 0.0 3.6 4 1 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 ETO28512.1 - 2.9e-11 42.4 0.3 3.5e-06 26.7 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat PUF PF00806.14 ETO28512.1 - 0.042 13.3 0.0 0.66 9.5 0.0 2.5 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat NRDE PF05742.7 ETO28512.1 - 0.049 12.9 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 NRDE protein CENP-O PF09496.5 ETO28515.1 - 0.042 14.0 1.5 0.21 11.8 0.1 2.8 2 0 0 2 2 2 0 Cenp-O kinetochore centromere component DUF3439 PF11921.3 ETO28515.1 - 0.099 12.3 1.1 0.26 11.0 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) MT PF12777.2 ETO28516.1 - 7.6e-24 84.0 26.3 1.7e-19 69.8 3.3 2.5 2 1 0 2 2 2 2 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 ETO28516.1 - 5e-12 45.1 2.9 1.1e-11 44.0 0.1 2.3 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 ETO28516.1 - 0.0027 16.7 0.8 0.0052 15.8 0.5 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Borrelia_P83 PF05262.6 ETO28516.1 - 1.7 6.8 26.8 0.45 8.7 8.4 2.2 2 0 0 2 2 2 0 Borrelia P83/100 protein DUF4570 PF15134.1 ETO28516.1 - 9.8 6.0 16.3 0.043 13.6 2.3 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4570) AAA_9 PF12781.2 ETO28517.1 - 3.1e-34 117.8 1.2 3.5e-34 117.6 0.8 1.0 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 Remorin_C PF03763.8 ETO28517.1 - 0.012 15.1 0.9 0.016 14.7 0.4 1.3 1 1 0 1 1 1 0 Remorin, C-terminal region Dynein_heavy PF03028.10 ETO28518.1 - 8.1e-178 592.7 0.0 2.4e-177 591.1 0.0 1.7 1 1 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor Cation_ATPase_C PF00689.16 ETO28519.1 - 3.6e-16 59.2 6.9 3.6e-16 59.2 4.8 1.9 1 1 1 2 2 2 1 Cation transporting ATPase, C-terminus MotB_plug PF13677.1 ETO28519.1 - 0.09 12.1 0.1 0.23 10.8 0.1 1.6 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB Hydrolase PF00702.21 ETO28520.1 - 3.8e-18 66.7 0.0 5.4e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 ETO28520.1 - 5.9e-15 55.2 1.2 5.9e-15 55.2 0.8 2.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus HAD PF12710.2 ETO28520.1 - 0.00018 21.7 0.0 0.00039 20.6 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 ETO28520.1 - 0.0032 17.0 6.9 0.0076 15.8 1.1 2.5 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase NTP_transf_2 PF01909.18 ETO28521.1 - 0.0003 21.0 0.1 0.00088 19.5 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyltransferase domain TraL PF07178.6 ETO28521.1 - 0.049 13.6 0.0 0.093 12.7 0.0 1.4 1 0 0 1 1 1 0 TraL protein Ndc1_Nup PF09531.5 ETO28521.1 - 0.55 8.5 5.6 0.92 7.8 3.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UPF0560 PF10577.4 ETO28521.1 - 5.6 5.1 15.8 8.2 4.5 10.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Paramyxo_ncap PF00973.14 ETO28521.1 - 6.1 5.4 9.7 25 3.3 7.5 1.5 2 0 0 2 2 2 0 Paramyxovirus nucleocapsid protein DUF4500 PF14937.1 ETO28523.1 - 0.00099 18.8 0.1 0.23 11.2 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4500) UPF0542 PF15086.1 ETO28523.1 - 0.039 13.6 2.6 0.054 13.2 1.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 Myb_DNA-bind_5 PF13873.1 ETO28523.1 - 0.047 13.5 3.0 0.07 13.0 2.1 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain COX4 PF02936.9 ETO28523.1 - 0.067 12.9 0.1 0.073 12.8 0.1 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV EphA2_TM PF14575.1 ETO28523.1 - 0.076 13.4 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3007 PF11460.3 ETO28523.1 - 0.1 12.6 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) DUF4199 PF13858.1 ETO28523.1 - 0.12 12.3 0.1 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Kelch_2 PF07646.10 ETO28523.1 - 0.17 11.7 0.2 0.27 11.0 0.1 1.3 1 0 0 1 1 1 0 Kelch motif S1FA PF04689.8 ETO28523.1 - 0.23 11.3 2.4 0.32 10.8 1.6 1.2 1 0 0 1 1 1 0 DNA binding protein S1FA ETRAMP PF09716.5 ETO28523.1 - 2.9 7.8 6.3 4.8 7.2 4.4 1.5 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF59 PF01883.14 ETO28524.1 - 2.1e-12 46.8 0.0 3.5e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF59 IncA PF04156.9 ETO28525.1 - 0.0046 16.5 4.1 0.0046 16.5 2.8 4.5 3 1 1 4 4 4 3 IncA protein Surfac_D-trimer PF09006.6 ETO28525.1 - 3.6 7.3 6.4 30 4.4 0.0 2.9 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation MAD PF05557.8 ETO28525.1 - 7.6 4.4 64.4 2.3 6.1 1.8 3.1 2 1 0 2 2 2 0 Mitotic checkpoint protein Tubulin PF00091.20 ETO28527.1 - 1.5e-60 204.7 0.0 2e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.1 ETO28527.1 - 0.13 11.7 0.0 0.32 10.4 0.0 1.7 2 1 1 3 3 3 0 Tubulin domain Misat_Tub_SegII PF10644.4 ETO28527.1 - 0.13 12.2 0.2 0.38 10.8 0.0 1.9 2 0 0 2 2 2 0 Misato Segment II tubulin-like domain Pkinase PF00069.20 ETO28528.1 - 0.068 12.3 0.0 0.088 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain zf-TRAF PF02176.13 ETO28529.1 - 2.7e-19 69.3 28.9 4.8e-12 46.0 4.2 4.8 3 1 1 4 4 4 3 TRAF-type zinc finger PH PF00169.24 ETO28529.1 - 1.2e-06 28.6 3.2 2.8e-06 27.4 0.0 2.8 3 0 0 3 3 3 1 PH domain Sina PF03145.11 ETO28529.1 - 0.00012 21.7 15.0 0.001 18.7 3.3 2.7 1 1 1 2 2 2 2 Seven in absentia protein family PH_11 PF15413.1 ETO28529.1 - 0.00045 20.4 0.1 0.0019 18.4 0.0 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 ETO28529.1 - 0.013 15.3 0.0 0.064 13.1 0.0 2.1 1 0 0 1 1 1 0 PH domain PH_8 PF15409.1 ETO28529.1 - 0.04 14.0 0.4 0.17 11.9 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain DUF1415 PF07209.7 ETO28529.1 - 0.073 12.8 1.7 0.16 11.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1415) Pkinase PF00069.20 ETO28530.1 - 2.3e-11 43.3 0.0 4.5e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Zip PF02535.17 ETO28530.1 - 0.2 10.6 0.4 0.24 10.3 0.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Ins134_P3_kin PF05770.6 ETO28531.1 - 5e-17 61.8 1.0 1.8e-10 40.3 0.1 2.8 3 0 0 3 3 3 2 Inositol 1, 3, 4-trisphosphate 5/6-kinase HAD_2 PF13419.1 ETO28532.1 - 3.4e-13 50.1 0.1 3.6e-12 46.8 0.1 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ETO28532.1 - 3.3e-07 29.9 0.0 6.3e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Ins134_P3_kin PF05770.6 ETO28532.1 - 0.00089 18.3 0.1 0.0049 15.9 0.0 2.0 2 0 0 2 2 2 1 Inositol 1, 3, 4-trisphosphate 5/6-kinase PGP_phosphatase PF09419.5 ETO28532.1 - 0.0014 18.0 0.1 0.022 14.1 0.0 2.4 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase PNK3P PF08645.6 ETO28532.1 - 0.01 15.3 0.6 0.032 13.6 0.1 2.0 2 1 0 2 2 2 0 Polynucleotide kinase 3 phosphatase Hydrolase PF00702.21 ETO28532.1 - 0.04 14.3 0.0 0.18 12.2 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Peptidase_S49_N PF08496.5 ETO28534.1 - 4.4 7.0 9.6 2.7 7.7 4.8 1.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF3899 PF13038.1 ETO28534.1 - 8.5 6.6 7.3 11 6.1 3.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) SAM_2 PF07647.12 ETO28535.1 - 5.2e-06 26.2 1.6 3.6e-05 23.5 0.1 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO28535.1 - 0.00027 21.0 1.7 0.00043 20.4 0.2 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 ETO28535.1 - 0.0017 18.1 0.3 0.54 10.0 0.0 2.3 2 0 0 2 2 2 2 Sterile alpha motif (SAM)/Pointed domain Atrophin-1 PF03154.10 ETO28535.1 - 0.011 13.9 3.8 0.013 13.6 2.6 1.1 1 0 0 1 1 1 0 Atrophin-1 family Vfa1 PF08432.5 ETO28535.1 - 0.16 11.9 10.8 0.24 11.3 7.5 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4407 PF14362.1 ETO28535.1 - 0.27 10.1 1.1 0.39 9.6 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peroxin-13_N PF04088.8 ETO28535.1 - 0.3 11.0 1.1 0.51 10.2 0.7 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region SHR3_chaperone PF08229.6 ETO28535.1 - 0.44 9.4 2.8 0.71 8.7 1.9 1.3 1 0 0 1 1 1 0 ER membrane protein SH3 YqfQ PF14181.1 ETO28535.1 - 0.46 10.5 5.8 0.71 9.8 4.0 1.2 1 0 0 1 1 1 0 YqfQ-like protein Peptidase_S49_N PF08496.5 ETO28535.1 - 0.54 10.0 4.7 0.83 9.4 3.3 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2956 PF11169.3 ETO28535.1 - 9.4 6.2 11.5 7.7 6.5 6.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) DUF2371 PF10177.4 ETO28536.1 - 0.57 10.0 2.9 0.36 10.7 0.4 1.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) DUF912 PF06024.7 ETO28538.1 - 8.3 6.5 9.8 1.4 8.9 0.0 2.8 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Alba PF01918.16 ETO28539.1 - 0.052 13.1 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Alba Pkinase PF00069.20 ETO28542.1 - 6.6e-63 212.2 0.3 9.8e-63 211.7 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO28542.1 - 3.8e-41 140.8 0.2 1.9e-40 138.5 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO28542.1 - 1.4e-06 27.5 0.0 6.3e-06 25.3 0.0 1.9 2 1 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.4 ETO28542.1 - 0.0011 18.3 0.0 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 ETO28542.1 - 0.0018 17.6 0.4 0.0041 16.5 0.1 1.7 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 ETO28542.1 - 0.029 13.4 0.7 0.048 12.7 0.5 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO28542.1 - 0.15 11.7 2.4 0.3 10.7 0.2 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Borrelia_REV PF03978.8 ETO28543.1 - 0.098 12.3 0.8 0.2 11.3 0.1 1.7 2 0 0 2 2 2 0 Borrelia burgdorferi REV protein WD40 PF00400.27 ETO28545.1 - 2.5e-10 39.8 1.9 0.23 11.4 0.1 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat PIP5K PF01504.13 ETO28546.1 - 6.9e-63 212.0 3.2 1.1e-62 211.4 2.2 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF308 PF03729.8 ETO28547.1 - 0.011 15.6 3.2 0.68 9.9 0.2 2.3 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) DUF4064 PF13273.1 ETO28547.1 - 0.025 14.6 0.7 7.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) L_HGMIC_fpl PF10242.4 ETO28547.1 - 0.13 12.2 3.4 0.089 12.7 0.3 1.9 2 0 0 2 2 2 0 Lipoma HMGIC fusion partner-like protein TRIQK PF15168.1 ETO28547.1 - 0.4 10.6 2.1 0.62 10.0 0.0 2.2 3 0 0 3 3 3 0 Triple QxxK/R motif-containing protein family SdpI PF13630.1 ETO28547.1 - 2.7 7.7 6.6 2.2 8.0 0.2 2.2 2 0 0 2 2 2 0 SdpI/YhfL protein family Pox_VP8_L4R PF04498.7 ETO28549.1 - 0.016 14.5 1.6 0.016 14.5 1.1 1.8 2 0 0 2 2 2 0 Poxvirus nucleic acid binding protein VP8/L4R Cwf_Cwc_15 PF04889.7 ETO28550.1 - 0.023 14.4 6.2 0.03 14.0 4.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Rgp1 PF08737.5 ETO28550.1 - 0.13 11.3 2.2 0.15 11.1 1.5 1.1 1 0 0 1 1 1 0 Rgp1 Cut8_N PF14482.1 ETO28551.1 - 0.025 14.5 0.1 0.025 14.5 0.1 3.3 2 1 2 4 4 4 0 Cut8 proteasome-binding domain PS_Dcarbxylase PF02666.10 ETO28552.1 - 0.05 12.9 0.5 0.053 12.8 0.3 1.1 1 0 0 1 1 1 0 Phosphatidylserine decarboxylase DUF2967 PF11179.3 ETO28552.1 - 0.12 11.8 5.1 0.14 11.6 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) DUF912 PF06024.7 ETO28552.1 - 0.81 9.7 11.6 1.2 9.2 0.8 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TMEM51 PF15345.1 ETO28552.1 - 1.1 8.8 6.3 1.4 8.5 4.4 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Aldo_ket_red PF00248.16 ETO28553.1 - 4.7e-57 192.9 0.0 5.4e-57 192.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FBPase PF00316.15 ETO28554.1 - 2.4e-72 243.5 0.0 2.7e-72 243.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Helicase_C PF00271.26 ETO28555.1 - 5.4e-21 74.2 0.3 8.4e-20 70.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Mitofilin PF09731.4 ETO28556.1 - 0.88 8.1 25.0 1.1 7.8 17.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF2775 PF10950.3 ETO28557.1 - 0.45 10.7 5.9 0.38 10.9 2.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2775) Tubulin_C PF03953.12 ETO28558.1 - 5.7e-49 165.3 0.2 1.2e-48 164.2 0.1 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 ETO28558.1 - 2.6e-10 40.4 0.1 6.3e-10 39.2 0.1 1.6 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain RasGAP PF00616.14 ETO28558.1 - 0.056 13.1 0.1 0.11 12.1 0.0 1.7 1 1 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase DUF4611 PF15387.1 ETO28558.1 - 0.35 11.0 4.3 2 8.5 3.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Tubulin PF00091.20 ETO28559.1 - 5.7e-48 163.5 0.0 6.6e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.4 ETO28559.1 - 3.1e-06 27.2 0.0 4.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 ETO28559.1 - 0.14 11.5 0.0 0.31 10.4 0.0 1.5 2 0 0 2 2 2 0 Tubulin domain zf-C3HC4_2 PF13923.1 ETO28560.1 - 0.043 13.8 12.5 0.098 12.7 8.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Secretin_N_2 PF07655.8 ETO28560.1 - 0.071 13.5 15.9 0.23 11.8 11.0 1.9 1 0 0 1 1 1 0 Secretin N-terminal domain zf-RING_2 PF13639.1 ETO28560.1 - 0.11 12.3 11.6 0.089 12.6 6.8 1.8 2 0 0 2 2 2 0 Ring finger domain zf-MIZ PF02891.15 ETO28560.1 - 0.36 10.3 8.0 0.97 9.0 5.6 1.8 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C3HC4 PF00097.20 ETO28560.1 - 0.42 10.3 11.2 1.1 8.9 7.8 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO28560.1 - 0.58 9.9 10.7 1.4 8.7 7.4 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 ETO28560.1 - 0.84 9.4 10.2 2.4 7.9 7.1 1.9 1 0 0 1 1 1 0 RING-type zinc-finger Curto_V3 PF07436.6 ETO28561.1 - 0.15 12.2 0.5 0.34 11.0 0.1 1.7 1 1 1 2 2 2 0 Curtovirus V3 protein NAD_binding_2 PF03446.10 ETO28562.1 - 8e-36 123.3 0.3 1.8e-33 115.6 0.2 2.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 6PGD PF00393.14 ETO28562.1 - 2.3e-29 102.5 4.8 1.2e-18 67.3 0.2 2.2 1 1 1 2 2 2 2 6-phosphogluconate dehydrogenase, C-terminal domain 3HCDH_N PF02737.13 ETO28562.1 - 0.0048 16.5 0.1 0.013 15.1 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 ETO28562.1 - 0.042 14.2 0.1 0.14 12.5 0.1 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent MVP_shoulder PF11978.3 ETO28563.1 - 0.13 12.1 0.4 4 7.3 0.0 2.5 2 0 0 2 2 2 0 Shoulder domain DNA_pol_phi PF04931.8 ETO28564.1 - 5.3 4.6 10.4 0.034 11.9 1.3 1.5 2 0 0 2 2 2 0 DNA polymerase phi AhpC-TSA PF00578.16 ETO28565.1 - 1.3e-39 134.6 0.3 2.6e-39 133.7 0.0 1.6 2 1 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 ETO28565.1 - 9.7e-16 57.6 0.0 1.4e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 ETO28565.1 - 3e-08 33.1 0.0 5.7e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AAA PF00004.24 ETO28566.1 - 3.9e-05 23.8 0.0 8.6e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Pox_P21 PF05313.7 ETO28566.1 - 0.0042 16.3 1.1 0.0069 15.6 0.8 1.3 1 0 0 1 1 1 1 Poxvirus P21 membrane protein AAA_22 PF13401.1 ETO28566.1 - 0.014 15.5 0.2 0.14 12.3 0.0 2.5 2 1 1 3 3 3 0 AAA domain Resolvase PF00239.16 ETO28566.1 - 0.11 12.3 0.1 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Resolvase, N terminal domain DUF2721 PF11026.3 ETO28566.1 - 0.28 10.8 2.3 0.6 9.7 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Phospholamban PF04272.9 ETO28566.1 - 8.7 5.8 9.1 3.5 7.1 4.1 2.0 1 1 1 2 2 2 0 Phospholamban AAA_22 PF13401.1 ETO28567.1 - 0.0037 17.4 0.6 0.016 15.3 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 ETO28567.1 - 0.0049 16.4 6.9 0.022 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 ETO28567.1 - 0.007 16.0 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain DUF3762 PF12591.3 ETO28567.1 - 0.013 15.4 0.4 0.49 10.4 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3762) AAA_16 PF13191.1 ETO28567.1 - 0.02 14.8 0.4 0.048 13.6 0.1 1.8 2 1 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 ETO28567.1 - 0.023 14.8 0.2 0.06 13.5 0.1 1.7 1 0 0 1 1 1 0 RNA helicase DUF87 PF01935.12 ETO28567.1 - 0.026 14.3 3.9 0.75 9.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA PF00004.24 ETO28567.1 - 0.069 13.3 1.6 0.32 11.1 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 ETO28567.1 - 0.18 12.0 4.0 4.9 7.4 0.1 2.2 2 0 0 2 2 2 0 ABC transporter AIG1 PF04548.11 ETO28567.1 - 0.26 10.3 0.1 0.26 10.3 0.1 2.2 2 0 0 2 2 2 0 AIG1 family CHD5 PF04420.9 ETO28567.1 - 1.9 8.1 4.3 7.7 6.1 2.2 2.1 1 1 0 2 2 2 0 CHD5-like protein Hemerythrin PF01814.18 ETO28568.1 - 1.7e-05 24.9 1.1 6e-05 23.2 0.8 1.7 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain ImcF-related_N PF14331.1 ETO28568.1 - 0.014 14.3 0.1 0.016 14.1 0.1 1.1 1 0 0 1 1 1 0 ImcF-related N-terminal domain DUF2972 PF11186.3 ETO28568.1 - 0.13 12.0 1.8 3 7.6 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2972) WD40 PF00400.27 ETO28569.1 - 1.7e-59 195.7 27.9 1.2e-11 43.9 0.2 7.2 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO28569.1 - 4.8e-08 31.5 6.7 0.014 13.5 0.4 5.2 1 1 4 5 5 5 5 Nucleoporin Nup120/160 HEAT PF02985.17 ETO28570.1 - 6.7e-13 47.5 3.4 0.38 10.9 0.0 9.3 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.1 ETO28570.1 - 4.6e-11 42.8 1.3 0.22 11.8 0.0 6.6 6 1 0 6 6 6 3 HEAT repeats ParcG PF10274.4 ETO28570.1 - 5e-08 33.0 3.6 0.00044 20.2 0.1 4.9 4 1 1 5 5 5 1 Parkin co-regulated protein HEAT_EZ PF13513.1 ETO28570.1 - 9.6e-08 32.3 0.1 0.17 12.4 0.5 6.6 6 1 1 7 7 7 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 ETO28570.1 - 0.015 15.6 4.3 0.32 11.4 0.1 5.0 4 1 1 6 6 6 0 Vacuolar 14 Fab1-binding region SICA_C PF12879.2 ETO28570.1 - 0.13 12.1 5.9 0.61 9.9 0.1 2.8 3 0 0 3 3 3 0 SICA C-terminal inner membrane domain Tubulin PF00091.20 ETO28571.1 - 3.8e-21 75.9 0.0 5.2e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO28571.1 - 1.6e-17 63.6 0.0 2.3e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Pkinase PF00069.20 ETO28572.1 - 1.3e-10 40.8 0.0 1.3e-10 40.8 0.0 2.7 4 0 0 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO28572.1 - 8.7e-05 21.7 0.4 0.00017 20.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase DUF936 PF06075.7 ETO28573.1 - 2.7 6.8 33.2 3.3 6.5 23.0 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) PWI PF01480.12 ETO28574.1 - 1.6e-07 31.2 0.7 6.4e-07 29.3 0.1 2.2 3 0 0 3 3 3 1 PWI domain Daxx PF03344.10 ETO28575.1 - 0.00089 17.8 11.2 0.00089 17.8 7.8 1.1 1 0 0 1 1 1 1 Daxx Family Nop14 PF04147.7 ETO28575.1 - 0.011 13.7 8.6 0.011 13.6 6.0 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 ETO28575.1 - 0.023 12.7 11.3 0.028 12.4 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF605 PF04652.11 ETO28575.1 - 0.065 12.6 18.7 0.085 12.2 12.9 1.1 1 0 0 1 1 1 0 Vta1 like TAFH PF07531.9 ETO28575.1 - 0.091 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 NHR1 homology to TAF Spt5_N PF11942.3 ETO28575.1 - 0.15 12.7 13.1 0.21 12.2 8.3 1.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Rep_4 PF05797.6 ETO28575.1 - 0.2 10.3 7.3 0.29 9.7 5.1 1.2 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) Lin-8 PF03353.10 ETO28575.1 - 0.36 10.0 11.6 0.44 9.7 8.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TEX19 PF15553.1 ETO28575.1 - 0.75 9.6 4.3 1.3 8.8 3.0 1.4 1 0 0 1 1 1 0 Testis-expressed protein 19 RRN3 PF05327.6 ETO28575.1 - 0.93 7.5 8.7 1.2 7.1 6.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nucleoplasmin PF03066.10 ETO28575.1 - 0.99 8.9 8.8 1.7 8.1 6.1 1.5 1 0 0 1 1 1 0 Nucleoplasmin DUF4637 PF15470.1 ETO28575.1 - 2.2 7.8 4.1 3.1 7.3 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) FAM176 PF14851.1 ETO28575.1 - 4.4 6.9 11.0 9.7 5.8 7.6 1.6 1 0 0 1 1 1 0 FAM176 family p47_phox_C PF08944.6 ETO28575.1 - 9.9 6.4 9.0 2.2e+02 2.1 6.3 2.7 1 1 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain Astro_capsid PF03115.9 ETO28576.1 - 2.1 6.4 14.7 2.7 6.1 10.2 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF2681 PF10883.3 ETO28579.1 - 0.24 11.5 0.0 0.24 11.5 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) DUF3357 PF11837.3 ETO28579.1 - 1.2 8.9 5.9 0.56 10.0 0.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) Menin PF05053.8 ETO28579.1 - 2.3 6.2 7.6 0.073 11.2 1.1 1.5 2 0 0 2 2 2 0 Menin NST1 PF13945.1 ETO28579.1 - 3.3 7.7 15.1 0.7 9.9 0.4 3.2 3 0 0 3 3 3 0 Salt tolerance down-regulator DUF912 PF06024.7 ETO28579.1 - 6.5 6.8 14.8 0.79 9.8 3.5 3.2 3 1 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1754 PF08555.5 ETO28579.1 - 8.1 7.1 19.2 0.2 12.2 0.6 3.0 2 1 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Ras PF00071.17 ETO28580.1 - 2.5e-20 72.4 0.9 1.5e-16 60.2 0.0 3.6 3 0 0 3 3 3 2 Ras family Miro PF08477.8 ETO28580.1 - 9.7e-06 26.0 0.4 0.024 15.1 0.0 3.3 3 0 0 3 3 3 2 Miro-like protein AAA_16 PF13191.1 ETO28580.1 - 0.002 18.1 0.0 0.0059 16.6 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 ETO28580.1 - 0.0041 17.2 0.0 0.014 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ETO28580.1 - 0.12 13.2 2.2 0.23 12.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 ETO28580.1 - 0.18 11.2 0.0 0.43 10.0 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_19 PF13245.1 ETO28580.1 - 0.2 11.4 0.0 0.4 10.4 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain TPR_11 PF13414.1 ETO28581.1 - 1.7e-24 85.2 4.8 7.5e-10 38.3 0.0 4.2 3 1 1 4 4 4 3 TPR repeat TPR_17 PF13431.1 ETO28581.1 - 2.9e-20 70.7 3.3 0.0011 18.9 0.0 6.6 7 1 0 7 7 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO28581.1 - 5.3e-19 66.5 2.1 0.00046 19.9 0.3 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO28581.1 - 1.7e-18 65.3 5.4 7.4e-07 28.5 0.3 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO28581.1 - 4.7e-10 38.5 0.3 0.072 12.9 0.1 5.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO28581.1 - 9.3e-10 38.3 2.3 1.5e-06 28.0 0.5 3.4 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO28581.1 - 1.1e-09 38.0 0.3 0.00014 22.1 0.2 5.4 2 2 4 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO28581.1 - 3.4e-09 37.1 0.0 0.00038 21.0 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO28581.1 - 3.5e-07 29.5 0.0 0.26 11.1 0.0 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO28581.1 - 4.5e-07 29.8 3.7 1.1 9.8 0.1 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO28581.1 - 6.1e-06 26.4 2.5 0.0039 17.5 0.1 3.7 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 ETO28581.1 - 0.00018 21.5 0.2 0.03 14.4 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETO28581.1 - 0.0007 19.3 0.3 0.047 13.5 0.0 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat Coatomer_E PF04733.9 ETO28581.1 - 0.0062 15.7 0.2 0.39 9.8 0.0 2.3 2 0 0 2 2 2 1 Coatomer epsilon subunit Apc3 PF12895.2 ETO28581.1 - 0.019 15.0 6.8 1.5 9.0 0.1 3.6 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 PEX11 PF05648.9 ETO28582.1 - 4.3e-22 78.4 3.8 2.8e-20 72.5 2.7 2.0 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Hydrolase_like2 PF13246.1 ETO28583.1 - 1.1e-09 38.0 0.0 3.2e-09 36.6 0.0 1.8 1 1 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Tropomyosin_1 PF12718.2 ETO28584.1 - 0.0027 17.5 6.1 0.0027 17.5 4.2 2.6 3 0 0 3 3 3 1 Tropomyosin like MMR_HSR1 PF01926.18 ETO28585.1 - 7.4e-05 22.6 0.4 0.00032 20.6 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 ETO28585.1 - 0.00049 19.3 1.9 0.0012 18.1 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 ETO28585.1 - 0.003 17.0 0.1 0.0095 15.3 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 ETO28585.1 - 0.0045 17.2 2.0 0.01 16.1 0.0 2.6 2 1 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 ETO28585.1 - 0.0048 16.3 0.1 0.01 15.3 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.1 ETO28585.1 - 0.0052 16.7 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 ETO28585.1 - 0.0076 15.2 0.1 0.028 13.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_10 PF12846.2 ETO28585.1 - 0.011 15.2 0.3 0.072 12.5 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain Zein-binding PF04576.10 ETO28585.1 - 0.011 15.7 0.2 0.039 14.0 0.1 2.0 1 0 0 1 1 1 0 Zein-binding AAA_25 PF13481.1 ETO28585.1 - 0.016 14.5 0.6 0.043 13.1 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 ETO28585.1 - 0.037 14.0 0.4 0.46 10.4 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 ETO28585.1 - 0.11 12.2 0.1 0.35 10.6 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain Zip PF02535.17 ETO28585.1 - 2.3 7.1 5.6 3.8 6.4 3.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter WD40 PF00400.27 ETO28586.1 - 1.6e-57 189.4 14.4 4.2e-12 45.4 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO28586.1 - 1.1e-10 41.5 0.7 0.00014 21.6 0.1 3.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO28586.1 - 4.1e-07 28.5 2.0 0.014 13.5 0.1 3.4 2 1 1 3 3 3 2 Nucleoporin Nup120/160 DPPIV_N PF00930.16 ETO28586.1 - 1.1e-06 27.4 0.3 0.19 10.3 0.0 4.5 1 1 4 5 5 5 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nucleoporin_N PF08801.6 ETO28586.1 - 1.6e-05 23.8 11.4 0.02 13.6 3.0 4.6 1 1 1 2 2 2 2 Nup133 N terminal like PD40 PF07676.7 ETO28586.1 - 1.7e-05 24.3 4.4 2.2 8.0 0.0 5.5 6 0 0 6 6 5 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO28586.1 - 0.00012 20.5 0.1 0.0002 19.7 0.0 1.5 1 1 0 1 1 1 1 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 ETO28586.1 - 0.00033 19.8 3.1 19 4.7 0.0 5.5 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature Coatomer_WDAD PF04053.9 ETO28586.1 - 0.00035 19.4 1.3 0.0066 15.3 0.3 2.7 1 1 1 2 2 2 1 Coatomer WD associated region Utp8 PF10395.4 ETO28586.1 - 0.00052 18.4 0.1 0.00076 17.9 0.0 1.2 1 0 0 1 1 1 1 Utp8 family Hira PF07569.6 ETO28586.1 - 0.0014 17.8 0.6 0.14 11.3 0.0 3.4 2 1 2 4 4 4 1 TUP1-like enhancer of split Resistin PF06954.6 ETO28586.1 - 0.0029 17.8 1.8 0.6 10.4 0.1 3.4 2 2 1 3 3 3 1 Resistin PQQ_2 PF13360.1 ETO28586.1 - 0.0078 15.6 0.1 0.018 14.5 0.0 1.9 1 1 0 1 1 1 1 PQQ-like domain IKI3 PF04762.7 ETO28586.1 - 0.015 13.1 0.6 0.041 11.7 0.4 1.7 1 1 0 1 1 1 0 IKI3 family KH_1 PF00013.24 ETO28586.1 - 0.05 13.2 0.1 0.27 10.8 0.0 2.3 1 0 0 1 1 1 0 KH domain Colicin_Ia PF11504.3 ETO28586.1 - 0.17 11.8 1.1 44 4.0 0.0 3.9 5 0 0 5 5 4 0 Colicin Ia 2OG-FeII_Oxy PF03171.15 ETO28587.1 - 1.4e-09 38.1 2.4 6e-09 36.1 0.1 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 ETO28588.1 - 3.4e-15 56.5 0.0 6.1e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETO28588.1 - 3.6e-07 30.4 0.1 3.8e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Innexin PF00876.13 ETO28588.1 - 0.072 12.1 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Innexin DUF4140 PF13600.1 ETO28589.1 - 2.1 8.8 11.4 2 8.9 1.4 3.3 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Kelch_6 PF13964.1 ETO28590.1 - 5.6e-07 29.4 4.8 0.057 13.6 0.0 4.9 4 2 1 5 5 5 2 Kelch motif Kelch_5 PF13854.1 ETO28590.1 - 5.7e-06 26.1 2.2 0.036 14.0 0.1 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO28590.1 - 1.8e-05 24.1 2.9 0.053 13.0 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO28590.1 - 5.2e-05 22.9 1.7 0.011 15.5 0.0 3.8 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO28590.1 - 0.0019 17.8 6.6 0.072 12.8 0.1 4.1 4 0 0 4 4 4 1 Kelch motif Daxx PF03344.10 ETO28591.1 - 0.12 10.8 31.3 0.13 10.6 21.7 1.1 1 0 0 1 1 1 0 Daxx Family Podoplanin PF05808.6 ETO28591.1 - 0.24 10.9 1.7 0.19 11.2 0.1 1.6 1 1 1 2 2 2 0 Podoplanin Nop14 PF04147.7 ETO28591.1 - 1.3 6.8 33.8 1.7 6.4 23.4 1.2 1 0 0 1 1 1 0 Nop14-like family DUF1625 PF07787.7 ETO28591.1 - 3.2 6.9 13.7 5.8 6.0 9.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) BTB PF00651.26 ETO28592.1 - 2.6e-17 62.8 0.0 5e-17 61.8 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.17 ETO28592.1 - 0.06 13.5 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Abhydrolase_6 PF12697.2 ETO28593.1 - 0.0043 16.9 0.0 0.0063 16.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 ETO28593.1 - 0.023 14.1 0.1 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative esterase PX PF00787.19 ETO28594.1 - 8.2e-13 48.1 1.0 1e-12 47.8 0.7 1.2 1 0 0 1 1 1 1 PX domain Ribophorin_I PF04597.9 ETO28595.1 - 1.3e-53 182.0 1.1 1.8e-53 181.6 0.8 1.1 1 0 0 1 1 1 1 Ribophorin I ETRAMP PF09716.5 ETO28595.1 - 0.69 9.9 5.0 1 9.3 0.0 2.2 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Wbp11 PF09429.5 ETO28595.1 - 2.4 8.2 9.5 3.5 7.6 6.6 1.3 1 0 0 1 1 1 0 WW domain binding protein 11 PRY PF13765.1 ETO28596.1 - 0.048 13.1 1.0 0.15 11.5 0.0 2.2 2 0 0 2 2 2 0 SPRY-associated domain DUF3753 PF12575.3 ETO28596.1 - 0.097 12.4 1.3 0.25 11.1 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Mitoc_L55 PF09776.4 ETO28598.1 - 0.055 13.0 0.1 0.055 13.0 0.0 2.5 2 1 1 3 3 3 0 Mitochondrial ribosomal protein L55 RRM_1 PF00076.17 ETO28599.1 - 1.4e-24 85.4 0.0 2.1e-18 65.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO28599.1 - 1.1e-20 73.3 0.0 5.1e-15 55.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO28599.1 - 3.1e-17 62.1 0.0 3.9e-08 33.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETO28599.1 - 5.5e-05 22.8 0.1 0.0018 18.0 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Glyco_transf_92 PF01697.22 ETO28600.1 - 4.6e-16 58.9 5.7 2.1e-15 56.8 3.9 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.1 ETO28600.1 - 8.4e-09 35.6 0.3 2.8e-08 33.9 0.2 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 UPF0193 PF05250.6 ETO28601.1 - 0.0091 15.5 2.1 0.017 14.7 1.5 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) Ndc1_Nup PF09531.5 ETO28604.1 - 6.1 5.1 14.9 6.5 5.0 10.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup VWA_2 PF13519.1 ETO28605.1 - 2.9e-22 79.5 0.1 4.8e-22 78.8 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 ETO28605.1 - 2.5e-11 43.6 0.3 7.5e-11 42.0 0.1 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 ETO28605.1 - 0.00012 21.9 0.2 0.00055 19.8 0.1 2.1 1 1 0 1 1 1 1 vWA found in TerF C terminus VWA_3 PF13768.1 ETO28605.1 - 0.00039 20.1 0.2 0.0022 17.7 0.1 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain DUF2201 PF09967.4 ETO28605.1 - 0.028 14.4 0.3 1.4 8.9 0.2 2.7 1 1 0 1 1 1 0 VWA-like domain (DUF2201) VWA_CoxE PF05762.9 ETO28605.1 - 0.19 10.8 0.3 1.7 7.7 0.1 2.1 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein Sporozoite_P67 PF05642.6 ETO28607.1 - 0.04 11.7 5.9 0.042 11.7 4.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Prothymosin PF03247.9 ETO28607.1 - 0.11 12.6 14.5 0.11 12.6 9.8 1.4 1 1 0 1 1 1 0 Prothymosin/parathymosin family RXT2_N PF08595.6 ETO28607.1 - 0.75 9.5 5.7 0.98 9.2 4.0 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.4 ETO28607.1 - 1.9 7.1 8.9 1.8 7.1 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) zf-C2H2_4 PF13894.1 ETO28608.1 - 1.3e-07 31.4 11.4 0.00098 19.2 0.4 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 ETO28608.1 - 1.6e-07 31.2 11.6 0.003 17.8 0.7 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 ETO28608.1 - 1.8 8.7 8.7 5.4 7.2 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding AUX_IAA PF02309.11 ETO28609.1 - 0.16 11.7 7.1 0.31 10.7 2.1 2.2 2 0 0 2 2 2 0 AUX/IAA family CAP_N PF01213.14 ETO28609.1 - 0.2 10.9 8.4 0.39 9.9 5.8 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TMEM171 PF15471.1 ETO28609.1 - 0.35 9.6 2.0 0.72 8.5 1.4 1.5 1 0 0 1 1 1 0 Transmembrane protein family 171 Pex14_N PF04695.8 ETO28609.1 - 0.44 10.6 24.4 0.46 10.5 1.6 2.6 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Apc15p PF05841.6 ETO28609.1 - 0.54 11.0 22.1 0.26 12.0 1.6 2.6 2 0 0 2 2 2 0 Apc15p protein DUF1183 PF06682.7 ETO28609.1 - 0.96 8.9 10.5 2.6 7.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) Mito_fiss_reg PF05308.6 ETO28609.1 - 5.7 6.2 18.1 0.016 14.5 5.8 1.6 2 0 0 2 2 2 0 Mitochondrial fission regulator FAT PF02259.18 ETO28610.1 - 1.5e-71 241.2 20.1 3.4e-71 240.0 12.2 2.7 3 0 0 3 3 3 1 FAT domain PI3_PI4_kinase PF00454.22 ETO28610.1 - 5.7e-62 209.2 0.4 1.2e-61 208.2 0.3 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 ETO28610.1 - 1.1e-33 115.2 1.8 1.1e-32 112.0 1.3 3.0 1 0 0 1 1 1 1 Rapamycin binding domain DUF3385 PF11865.3 ETO28610.1 - 1e-22 80.7 0.1 1e-22 80.7 0.0 5.7 6 1 0 6 6 6 1 Domain of unknown function (DUF3385) HEAT_2 PF13646.1 ETO28610.1 - 3.6e-16 59.2 3.0 0.00024 21.3 0.0 6.8 5 2 1 6 6 5 3 HEAT repeats FATC PF02260.15 ETO28610.1 - 5.3e-14 51.3 0.4 1.9e-13 49.5 0.2 2.2 2 0 0 2 2 2 1 FATC domain HEAT_EZ PF13513.1 ETO28610.1 - 4.5e-09 36.5 3.5 0.2 12.1 0.0 8.4 9 2 2 11 11 10 2 HEAT-like repeat HEAT PF02985.17 ETO28610.1 - 1.3e-06 27.9 14.3 0.14 12.3 0.1 10.0 11 0 0 11 11 10 1 HEAT repeat Apc3 PF12895.2 ETO28610.1 - 0.00012 22.1 5.8 0.76 9.9 0.1 4.0 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 ETO28610.1 - 0.0016 18.3 3.1 0.18 11.7 0.3 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF2454 PF10521.4 ETO28610.1 - 0.026 13.5 14.4 0.31 9.9 0.7 4.8 3 1 2 5 5 5 0 Protein of unknown function (DUF2454) DUF1981 PF09324.5 ETO28610.1 - 0.12 11.8 8.5 0.27 10.8 0.3 4.9 5 1 1 6 6 6 0 Domain of unknown function (DUF1981) TPR_1 PF00515.23 ETO28610.1 - 0.15 11.6 2.8 4.2 7.1 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETO28610.1 - 0.61 10.1 7.3 2.4 8.3 0.1 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat Mg_trans_NIPA PF05653.9 ETO28612.1 - 1e-08 34.5 1.6 1e-08 34.5 1.1 1.9 2 1 0 2 2 2 1 Magnesium transporter NIPA Mg_trans_NIPA PF05653.9 ETO28613.1 - 7.7e-13 48.0 0.6 1.1e-12 47.5 0.4 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 ETO28613.1 - 0.00027 20.9 3.8 0.00047 20.1 2.6 1.4 1 0 0 1 1 1 1 EamA-like transporter family EmrE PF13536.1 ETO28613.1 - 0.0024 18.0 5.7 0.0024 18.0 4.0 1.5 1 1 0 1 1 1 1 Multidrug resistance efflux transporter UPF0546 PF10639.4 ETO28613.1 - 0.015 15.0 0.7 0.029 14.1 0.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0546 Hydrolase_6 PF13344.1 ETO28613.1 - 0.064 13.1 2.1 0.13 12.1 1.5 1.7 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase MitMem_reg PF13012.1 ETO28614.1 - 2.7e-10 40.3 0.4 1.5e-09 37.9 0.1 1.9 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function DUF1993 PF09351.5 ETO28614.1 - 0.023 14.6 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) Eapp_C PF10238.4 ETO28615.1 - 1.1 9.2 27.7 0.39 10.6 2.6 3.4 3 0 0 3 3 3 0 E2F-associated phosphoprotein Secretin_N_2 PF07655.8 ETO28615.1 - 5.9 7.3 66.7 3.4 8.1 9.0 4.4 4 0 0 4 4 4 0 Secretin N-terminal domain Ras PF00071.17 ETO28616.1 - 4.2e-34 117.2 0.0 5.2e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO28616.1 - 2.2e-07 31.3 0.0 3.4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO28616.1 - 0.00055 19.2 0.0 0.00069 18.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Usp PF00582.21 ETO28617.1 - 4.8e-16 59.2 1.2 1.2e-15 57.9 0.8 1.7 1 1 0 1 1 1 1 Universal stress protein family FTR1 PF03239.9 ETO28617.1 - 0.093 11.6 0.1 0.14 11.0 0.1 1.2 1 0 0 1 1 1 0 Iron permease FTR1 family MarC PF01914.12 ETO28617.1 - 0.11 11.5 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 MarC family integral membrane protein Tfb4 PF03850.9 ETO28618.1 - 4.7e-16 58.8 0.1 6.5e-16 58.4 0.1 1.2 1 0 0 1 1 1 1 Transcription factor Tfb4 XRN_N PF03159.13 ETO28618.1 - 0.00043 19.7 0.0 0.00088 18.7 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus HA2 PF04408.18 ETO28618.1 - 0.026 14.5 0.7 0.21 11.6 0.2 2.5 1 1 1 2 2 2 0 Helicase associated domain (HA2) Tfb4 PF03850.9 ETO28619.1 - 5.1e-27 94.8 1.0 7.2e-27 94.3 0.7 1.2 1 0 0 1 1 1 1 Transcription factor Tfb4 PhnA_Zn_Ribbon PF08274.7 ETO28619.1 - 0.31 10.8 3.6 1.6 8.5 0.2 2.5 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-RING_4 PF14570.1 ETO28619.1 - 1.1 8.8 4.1 0.35 10.4 0.4 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain SOBP PF15279.1 ETO28620.1 - 0.00095 19.6 7.8 0.0015 18.9 5.4 1.4 1 1 0 1 1 1 1 Sine oculis-binding protein DUF4544 PF15077.1 ETO28621.1 - 4.5 6.7 7.7 9.6 5.6 5.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) Mlo PF03094.10 ETO28622.1 - 0.27 9.2 7.2 0.12 10.4 0.1 2.1 2 0 0 2 2 2 0 Mlo family ATG16 PF08614.6 ETO28623.1 - 4.8e-06 26.5 26.4 4.8e-06 26.5 18.3 6.0 3 3 3 6 6 6 2 Autophagy protein 16 (ATG16) DUF3735 PF12537.3 ETO28623.1 - 0.53 10.3 0.0 0.53 10.3 0.0 6.1 7 0 0 7 7 7 0 Protein of unknown function (DUF3735) DAGAT PF03982.8 ETO28625.1 - 1e-76 257.4 5.6 1.4e-52 178.2 0.1 3.1 1 1 2 3 3 3 3 Diacylglycerol acyltransferase DUF3450 PF11932.3 ETO28626.1 - 0.01 15.0 0.2 0.012 14.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Endostatin PF06482.6 ETO28626.1 - 0.027 13.8 0.1 0.03 13.7 0.1 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin U1snRNP70_N PF12220.3 ETO28626.1 - 0.37 11.1 2.9 0.49 10.7 2.0 1.2 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Kelch_6 PF13964.1 ETO28627.1 - 0.072 13.2 0.2 2.6 8.3 0.0 2.6 2 1 0 2 2 2 0 Kelch motif Ribosomal_L27e PF01777.13 ETO28627.1 - 0.17 12.0 1.4 0.26 11.4 0.1 1.9 2 0 0 2 2 2 0 Ribosomal L27e protein family FYVE PF01363.16 ETO28628.1 - 4.9e-10 39.1 15.9 4.9e-10 39.1 11.0 1.7 2 0 0 2 2 2 1 FYVE zinc finger GGDEF PF00990.16 ETO28630.1 - 3.5e-11 42.9 6.6 3.2e-07 30.0 0.2 3.6 2 1 1 3 3 3 3 GGDEF domain NodZ PF05830.6 ETO28631.1 - 2.1e-08 33.1 0.6 1.5e-06 27.0 0.0 2.7 3 0 0 3 3 3 2 Nodulation protein Z (NodZ) Aldedh PF00171.17 ETO28633.1 - 2.6e-137 457.9 0.0 9.8e-90 301.0 0.0 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.9 ETO28633.1 - 0.004 15.9 0.2 0.015 14.0 0.2 1.9 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) SRR1 PF07985.7 ETO28634.1 - 8.5e-09 35.2 0.4 1.1e-05 25.2 0.0 2.8 3 0 0 3 3 3 2 SRR1 RhoGEF PF00621.15 ETO28635.1 - 5.5e-19 68.7 5.6 9.4e-19 67.9 3.9 1.4 1 0 0 1 1 1 1 RhoGEF domain CARD PF00619.16 ETO28635.1 - 0.14 11.9 1.9 18 5.2 0.1 3.0 3 0 0 3 3 3 0 Caspase recruitment domain DUF972 PF06156.8 ETO28635.1 - 0.23 11.8 4.7 0.76 10.1 3.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF972) U1snRNP70_N PF12220.3 ETO28635.1 - 3.2 8.1 13.0 0.12 12.7 2.1 3.0 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Git3_C PF11970.3 ETO28636.1 - 0.31 10.8 6.1 0.24 11.1 0.7 2.5 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term Arc_PepC_II PF06847.6 ETO28636.1 - 9.7 6.7 7.0 0.93 9.9 0.0 2.8 3 1 0 3 3 3 0 Archaeal Peptidase A24 C-terminus Type II ABC2_membrane PF01061.19 ETO28637.1 - 1.2e-33 116.0 12.6 1.2e-33 116.0 8.8 2.3 3 0 0 3 3 3 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 ETO28637.1 - 2.2e-08 33.5 1.4 2.2e-08 33.5 1.0 1.4 2 0 0 2 2 2 1 ABC-2 family transporter protein DUF948 PF06103.6 ETO28638.1 - 0.51 10.2 2.7 1.2 9.0 1.8 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) SAM_2 PF07647.12 ETO28639.1 - 4.5e-09 36.0 0.0 1.3e-08 34.5 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO28639.1 - 5.8e-08 32.8 0.1 1.7e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) zf-C2H2 PF00096.21 ETO28639.1 - 1.9e-06 27.8 20.5 0.0018 18.5 2.2 4.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETO28639.1 - 1.1e-05 25.3 20.3 0.011 16.0 1.3 4.7 4 0 0 4 4 4 2 C2H2-type zinc finger DUF629 PF04780.7 ETO28639.1 - 0.00012 20.7 13.6 0.00086 17.9 0.5 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.2 ETO28639.1 - 0.00013 22.0 21.2 0.087 12.9 1.0 4.5 4 0 0 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 ETO28639.1 - 0.002 17.9 8.3 2.5 8.1 0.0 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.7 ETO28639.1 - 0.007 16.4 0.2 0.007 16.4 0.2 4.3 4 0 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 ETO28639.1 - 0.015 15.6 21.1 0.5 10.7 1.9 5.6 4 1 0 4 4 4 0 Zinc-finger double domain DUF336 PF03928.9 ETO28639.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF336) Prok-RING_1 PF14446.1 ETO28639.1 - 1.1 9.0 6.2 1.2 8.9 0.2 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-BED PF02892.10 ETO28639.1 - 3 7.6 21.8 1.2 9.0 3.0 4.8 4 0 0 4 4 4 0 BED zinc finger zf-met PF12874.2 ETO28639.1 - 5.4 7.3 10.6 8.9 6.6 0.0 4.2 3 1 1 4 4 4 0 Zinc-finger of C2H2 type MDFI PF15316.1 ETO28639.1 - 8.7 6.3 13.3 1.6 8.7 0.2 3.1 3 0 0 3 3 3 0 MyoD family inhibitor Hydrolase_4 PF12146.3 ETO28641.1 - 8e-11 41.6 0.3 7.5e-10 38.5 0.1 2.1 1 1 1 2 2 2 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 ETO28641.1 - 3.7e-07 30.0 0.0 5.7e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETO28641.1 - 8.3e-06 25.8 0.0 1.1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETO28641.1 - 0.0014 18.2 0.3 0.0021 17.6 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 ETO28641.1 - 0.14 11.5 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 ETO28642.1 - 4e-09 36.6 0.0 4.9e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETO28642.1 - 2.8e-06 27.1 0.0 3.3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETO28642.1 - 0.0015 17.7 0.2 0.0023 17.1 0.1 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 ETO28642.1 - 0.0032 16.9 0.0 0.0042 16.5 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 ETO28642.1 - 0.01 15.1 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 ETO28642.1 - 0.042 13.2 0.1 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF2738 PF10927.3 ETO28642.1 - 0.045 12.7 0.0 0.07 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) Abhydrolase_1 PF00561.15 ETO28642.1 - 0.052 13.0 0.0 0.074 12.5 0.0 1.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold Sugar_tr PF00083.19 ETO28643.1 - 4.9e-34 117.6 28.4 1.1e-18 67.0 3.4 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 ETO28643.1 - 1.2e-29 103.1 15.0 1.2e-20 73.5 1.7 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETO28643.1 - 1.2e-05 23.9 24.5 0.00028 19.4 2.4 4.6 3 1 2 5 5 5 3 MFS/sugar transport protein MFS_3 PF05977.8 ETO28643.1 - 0.0017 16.5 0.6 0.0017 16.5 0.4 2.0 2 1 0 2 2 2 1 Transmembrane secretion effector DUF4231 PF14015.1 ETO28643.1 - 0.65 9.9 6.3 6.3 6.8 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) UQ_con PF00179.21 ETO28644.1 - 1.4e-09 37.5 0.0 3.3e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DNA_pol_viral_N PF00242.12 ETO28644.1 - 0.38 9.7 9.5 0.53 9.2 6.6 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain LMBR1 PF04791.11 ETO28644.1 - 0.42 9.1 2.6 0.47 8.9 1.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1510 PF07423.6 ETO28644.1 - 2.1 7.6 11.2 3.5 6.9 7.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4482 PF14818.1 ETO28644.1 - 2.2 8.9 8.0 3.9 8.1 5.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4482) Acyl-thio_N PF12590.3 ETO28644.1 - 2.5 8.5 9.0 4 7.8 6.2 1.3 1 0 0 1 1 1 0 Acyl-ATP thioesterase DUF4250 PF14056.1 ETO28645.1 - 0.037 13.7 0.2 0.037 13.7 0.1 4.5 5 1 0 5 5 5 0 Domain of unknown function (DUF4250) YlqD PF11068.3 ETO28645.1 - 3.9 7.5 51.7 0.055 13.5 4.9 4.2 2 1 2 4 4 4 0 YlqD protein CAP_GLY PF01302.20 ETO28646.1 - 7.5e-06 25.5 0.5 7.5e-06 25.5 0.4 2.0 2 0 0 2 2 2 1 CAP-Gly domain tRNA_anti-codon PF01336.20 ETO28648.1 - 6.9e-05 22.6 0.1 0.34 10.7 0.0 2.6 3 1 0 3 3 3 2 OB-fold nucleic acid binding domain DUF223 PF02721.9 ETO28648.1 - 0.0025 17.8 0.1 0.0061 16.6 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function DUF223 CodY PF06018.9 ETO28648.1 - 0.041 13.1 0.3 0.054 12.7 0.2 1.2 1 0 0 1 1 1 0 CodY GAF-like domain Cu-oxidase_2 PF07731.9 ETO28650.1 - 5.6e-09 35.6 1.1 2.3e-08 33.6 0.3 2.4 3 0 0 3 3 3 1 Multicopper oxidase BRX PF08381.6 ETO28651.1 - 0.015 14.3 1.8 0.034 13.1 1.3 1.6 1 0 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 DUF573 PF04504.9 ETO28652.1 - 0.23 11.7 1.6 0.99 9.7 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF573 PAT1 PF09770.4 ETO28653.1 - 0.25 9.5 27.0 0.26 9.4 18.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF912 PF06024.7 ETO28654.1 - 6.6 6.8 7.2 5 7.2 1.1 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PH PF00169.24 ETO28655.1 - 1.6e-12 47.5 8.7 9.7e-05 22.5 0.1 3.9 4 0 0 4 4 4 3 PH domain PH_11 PF15413.1 ETO28655.1 - 8.9e-05 22.7 3.7 0.014 15.6 0.1 3.5 3 0 0 3 3 3 2 Pleckstrin homology domain CpeS PF09367.5 ETO28655.1 - 0.95 9.3 5.2 0.15 11.9 0.4 1.8 2 0 0 2 2 2 0 CpeS-like protein TEX19 PF15553.1 ETO28655.1 - 1.4 8.7 5.8 0.81 9.5 1.4 2.2 2 0 0 2 2 2 0 Testis-expressed protein 19 CENP-B_dimeris PF09026.5 ETO28655.1 - 4 7.7 10.6 1.1 9.5 1.1 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain TcdB_N PF12918.2 ETO28656.1 - 0.074 13.1 0.0 0.24 11.4 0.0 1.9 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain TIMELESS PF04821.9 ETO28657.1 - 5.6e-05 22.5 4.4 0.00016 21.0 2.0 2.2 2 1 0 2 2 2 1 Timeless protein UME PF08064.8 ETO28657.1 - 0.0043 16.9 1.0 0.063 13.2 0.1 2.7 3 0 0 3 3 3 1 UME (NUC010) domain Arm PF00514.18 ETO28657.1 - 0.01 15.6 4.1 1.4 8.8 0.2 4.2 3 1 1 4 4 4 0 Armadillo/beta-catenin-like repeat RICTOR_V PF14668.1 ETO28657.1 - 0.16 11.9 2.3 2.4 8.1 0.2 2.8 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 CM2 PF03021.9 ETO28657.1 - 1.1 8.7 5.8 3.5 7.1 0.0 3.1 3 0 0 3 3 3 0 Influenza C virus M2 protein V-ATPase_H_N PF03224.9 ETO28658.1 - 0.00022 20.4 3.9 0.00032 19.9 2.7 1.3 1 0 0 1 1 1 1 V-ATPase subunit H Pyr_redox_2 PF07992.9 ETO28659.1 - 4.1e-06 26.8 0.0 9.3e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETO28659.1 - 0.014 15.4 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETO28659.1 - 0.032 14.0 0.0 0.21 11.3 0.0 2.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 ETO28659.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF4619 PF15398.1 ETO28661.1 - 0.011 15.1 0.3 0.011 15.1 0.2 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4619) Sec1 PF00995.18 ETO28662.1 - 4.3e-34 118.0 0.0 4.9e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Trm112p PF03966.11 ETO28664.1 - 6.7e-08 32.7 0.0 2.6e-07 30.9 0.0 2.0 1 1 0 1 1 1 1 Trm112p-like protein Pox_Ag35 PF03286.9 ETO28664.1 - 0.00056 19.4 9.2 0.00065 19.2 6.4 1.3 1 0 0 1 1 1 1 Pox virus Ag35 surface protein Rtf2 PF04641.7 ETO28664.1 - 0.011 15.0 6.1 0.013 14.7 4.3 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger CENP-T PF15511.1 ETO28664.1 - 0.017 14.3 5.9 0.018 14.3 4.1 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF1510 PF07423.6 ETO28664.1 - 0.022 14.1 16.7 0.03 13.6 11.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Hid1 PF12722.2 ETO28664.1 - 0.048 11.3 6.1 0.051 11.2 4.2 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FYDLN_acid PF09538.5 ETO28664.1 - 0.055 14.0 18.7 0.096 13.2 12.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CobT PF06213.7 ETO28664.1 - 0.14 11.2 20.7 0.2 10.7 14.3 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.7 ETO28664.1 - 0.21 10.8 15.6 0.3 10.2 10.8 1.2 1 0 0 1 1 1 0 NOA36 protein DUF1168 PF06658.7 ETO28664.1 - 1.1 8.7 17.2 1.8 8.1 11.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Nop14 PF04147.7 ETO28664.1 - 1.7 6.4 23.3 2.2 6.1 16.1 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4175 PF13779.1 ETO28664.1 - 2 5.9 11.0 2.5 5.6 7.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FLO_LFY PF01698.11 ETO28664.1 - 5.5 5.7 10.1 7.7 5.2 7.0 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein CDC45 PF02724.9 ETO28664.1 - 5.6 4.8 21.0 7.9 4.3 14.5 1.1 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.6 ETO28664.1 - 6.2 6.2 26.4 2 7.8 16.2 1.7 2 0 0 2 2 2 0 PPP4R2 SDA1 PF05285.7 ETO28664.1 - 6.6 5.9 23.5 10 5.2 16.3 1.2 1 0 0 1 1 1 0 SDA1 Sec1 PF00995.18 ETO28665.1 - 7.5e-52 176.7 3.5 8.6e-52 176.5 2.4 1.0 1 0 0 1 1 1 1 Sec1 family YxiJ PF14176.1 ETO28665.1 - 0.046 13.8 1.5 0.26 11.3 0.6 2.4 2 0 0 2 2 2 0 YxiJ-like protein Peptidase_S9 PF00326.16 ETO28666.1 - 2.1e-50 170.8 0.0 1e-49 168.6 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 ETO28666.1 - 1.8e-11 43.9 0.1 2.3e-10 40.3 0.1 2.3 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DPPIV_N PF00930.16 ETO28666.1 - 1e-10 40.7 0.2 1.7e-10 40.0 0.1 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Esterase PF00756.15 ETO28666.1 - 1.3e-07 31.3 0.2 1.8e-06 27.5 0.1 2.2 1 1 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 ETO28666.1 - 1.7e-07 31.1 0.0 3.2e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETO28666.1 - 5.3e-07 29.7 0.0 1e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 ETO28666.1 - 0.00015 21.1 0.0 0.085 12.1 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 ETO28666.1 - 0.00094 18.8 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 ETO28666.1 - 0.0044 16.4 0.1 0.23 10.8 0.0 2.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S28 PF05577.7 ETO28666.1 - 0.0074 14.8 0.0 0.011 14.3 0.0 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase S28 DUF2048 PF09752.4 ETO28666.1 - 0.023 13.5 0.0 0.036 12.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) AXE1 PF05448.7 ETO28666.1 - 0.037 12.5 0.1 0.23 9.9 0.1 2.1 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.4 ETO28666.1 - 0.048 12.8 0.1 0.19 10.9 0.0 1.8 2 0 0 2 2 2 0 Esterase PHB depolymerase Tannase PF07519.6 ETO28666.1 - 0.063 11.9 0.0 3.1 6.3 0.0 2.2 2 0 0 2 2 2 0 Tannase and feruloyl esterase Nop14 PF04147.7 ETO28667.1 - 0.12 10.3 17.0 0.17 9.7 11.8 1.2 1 0 0 1 1 1 0 Nop14-like family Pex14_N PF04695.8 ETO28667.1 - 0.14 12.1 11.5 0.46 10.5 4.5 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Gti1_Pac2 PF09729.4 ETO28667.1 - 7.9 6.3 13.8 15 5.4 5.7 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family MORN PF02493.15 ETO28668.1 - 1.4e-11 43.3 25.8 0.0042 16.7 0.7 5.2 5 0 0 5 5 5 5 MORN repeat Rad33 PF08730.5 ETO28669.1 - 0.0084 15.5 1.1 0.011 15.1 0.8 1.2 1 0 0 1 1 1 1 Rad33 PAT1 PF09770.4 ETO28669.1 - 0.036 12.3 0.5 0.043 12.0 0.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ATP_bind_1 PF03029.12 ETO28670.1 - 1.8e-68 230.6 0.1 1e-67 228.1 0.0 1.9 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 ETO28670.1 - 0.00025 21.8 0.6 0.0026 18.5 0.0 2.5 3 0 0 3 3 2 1 AAA domain GTP_EFTU PF00009.22 ETO28670.1 - 0.00041 19.8 0.0 0.0017 17.8 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Sigma70_ner PF04546.8 ETO28670.1 - 0.0027 17.3 1.2 0.0027 17.3 0.8 2.1 2 0 0 2 2 2 1 Sigma-70, non-essential region AAA_22 PF13401.1 ETO28670.1 - 0.0027 17.8 0.0 0.12 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 ETO28670.1 - 0.0052 16.9 0.0 0.24 11.6 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 ETO28670.1 - 0.0064 16.7 2.6 0.057 13.7 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.1 ETO28670.1 - 0.0076 15.8 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETO28670.1 - 0.014 15.3 0.0 0.046 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain PP_M1 PF03012.9 ETO28670.1 - 0.045 13.1 1.8 0.065 12.5 1.2 1.2 1 0 0 1 1 1 0 Phosphoprotein Nrap PF03813.9 ETO28670.1 - 0.05 11.1 0.0 0.069 10.6 0.0 1.1 1 0 0 1 1 1 0 Nrap protein AAA_29 PF13555.1 ETO28670.1 - 0.058 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 ETO28670.1 - 0.059 13.6 0.1 0.24 11.7 0.0 2.0 3 0 0 3 3 2 0 ABC transporter AAA_33 PF13671.1 ETO28670.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 ETO28670.1 - 0.14 11.8 0.0 0.42 10.3 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PPR_2 PF13041.1 ETO28671.1 - 2e-05 24.4 8.5 0.29 11.1 0.0 5.2 5 0 0 5 5 5 2 PPR repeat family PPR_3 PF13812.1 ETO28671.1 - 0.00029 20.8 4.7 5.5 7.5 0.0 5.9 6 0 0 6 6 6 1 Pentatricopeptide repeat domain PPR PF01535.15 ETO28671.1 - 0.0065 16.3 4.5 7.5 6.7 0.0 4.8 5 0 0 5 5 5 2 PPR repeat ubiquitin PF00240.18 ETO28672.1 - 6.8e-18 63.8 0.0 1.1e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 ETO28672.1 - 2.6e-10 39.8 0.1 3.8e-10 39.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 ETO28672.1 - 7.9e-06 26.0 0.0 1.4e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain Claudin_2 PF13903.1 ETO28672.1 - 0.0044 16.7 0.2 0.0057 16.3 0.1 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF2407 PF10302.4 ETO28672.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain NKAIN PF05640.9 ETO28672.1 - 0.24 10.3 13.0 0.067 12.1 6.8 1.6 1 1 0 1 1 1 0 Na,K-Atpase Interacting protein MORN PF02493.15 ETO28673.1 - 1.2e-18 65.6 19.5 3.7e-07 29.5 0.8 3.7 4 0 0 4 4 4 3 MORN repeat Tropomyosin_1 PF12718.2 ETO28673.1 - 0.15 11.9 7.6 0.32 10.8 5.3 1.5 1 0 0 1 1 1 0 Tropomyosin like DUF342 PF03961.8 ETO28673.1 - 0.16 10.3 7.1 0.3 9.4 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TMF_DNA_bd PF12329.3 ETO28673.1 - 0.45 10.3 10.3 1.3 8.9 7.2 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Peptidase_S49_N PF08496.5 ETO28673.1 - 3.4 7.4 8.4 2.1 8.1 3.4 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Nop PF01798.13 ETO28674.1 - 0.054 12.7 0.0 0.078 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative snoRNA binding domain IBN_N PF03810.14 ETO28676.1 - 2e-05 24.4 0.1 8.2e-05 22.4 0.0 1.9 1 1 1 2 2 2 1 Importin-beta N-terminal domain CLASP_N PF12348.3 ETO28676.1 - 0.085 12.1 0.1 0.23 10.8 0.0 1.7 1 1 0 1 1 1 0 CLASP N terminal Scs3p PF10261.4 ETO28677.1 - 0.091 11.7 0.0 0.091 11.7 0.0 2.2 2 1 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM Ctr PF04145.10 ETO28677.1 - 0.98 9.4 0.0 0.98 9.4 0.0 4.1 3 1 0 3 3 3 0 Ctr copper transporter family SOBP PF15279.1 ETO28680.1 - 6.1 7.1 20.4 10 6.3 14.2 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein SET PF00856.23 ETO28681.1 - 4.5e-08 33.5 0.1 0.00046 20.5 0.0 2.4 1 1 1 2 2 2 2 SET domain DUF3439 PF11921.3 ETO28682.1 - 0.19 11.4 8.5 1 9.0 5.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Arm PF00514.18 ETO28683.1 - 2.2e-05 24.0 0.0 0.0035 17.1 0.0 3.1 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Cyclin_C PF02984.14 ETO28684.1 - 0.012 15.5 0.4 0.014 15.3 0.3 1.1 1 0 0 1 1 1 0 Cyclin, C-terminal domain DUF2779 PF11074.3 ETO28684.1 - 0.051 13.6 1.6 0.056 13.4 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function(DUF2779) RNA_pol_Rpb1_3 PF04983.13 ETO28684.1 - 0.076 12.7 1.0 0.076 12.7 0.7 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 3 DUF3688 PF12461.3 ETO28684.1 - 0.25 11.7 3.0 0.29 11.5 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3688) PBP1_TM PF14812.1 ETO28685.1 - 0.02 15.1 12.0 0.02 15.1 8.3 2.3 3 0 0 3 3 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HMG_box PF00505.14 ETO28685.1 - 0.041 14.1 4.9 0.041 14.1 3.4 3.2 3 0 0 3 3 3 0 HMG (high mobility group) box DNA_pol_phi PF04931.8 ETO28685.1 - 0.061 11.1 10.6 0.081 10.6 7.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Daxx PF03344.10 ETO28685.1 - 0.13 10.6 14.1 0.2 10.0 9.7 1.3 1 0 0 1 1 1 0 Daxx Family CENP-B_dimeris PF09026.5 ETO28685.1 - 0.16 12.1 12.5 0.3 11.3 8.7 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CobT PF06213.7 ETO28685.1 - 0.21 10.6 10.9 0.35 9.9 7.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RXT2_N PF08595.6 ETO28685.1 - 0.48 10.2 9.7 0.12 12.1 4.3 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal NOA36 PF06524.7 ETO28685.1 - 0.78 8.9 8.6 1.2 8.2 5.9 1.3 1 0 0 1 1 1 0 NOA36 protein TRAP_alpha PF03896.11 ETO28685.1 - 0.88 8.5 7.9 1.7 7.5 5.5 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nucleoplasmin PF03066.10 ETO28685.1 - 1 8.8 17.1 1.9 7.9 11.8 1.4 1 0 0 1 1 1 0 Nucleoplasmin GOLD_2 PF13897.1 ETO28685.1 - 1.1 9.4 5.5 2.5 8.3 3.8 1.6 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking FAM176 PF14851.1 ETO28685.1 - 1.1 8.9 13.2 0.053 13.2 5.2 1.7 2 0 0 2 2 2 0 FAM176 family Tom22 PF04281.8 ETO28685.1 - 1.1 8.7 8.8 3.1 7.3 6.1 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 CDC45 PF02724.9 ETO28685.1 - 1.1 7.1 15.0 1.7 6.5 10.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3537 PF12056.3 ETO28685.1 - 1.6 7.3 5.3 2.4 6.7 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) Sporozoite_P67 PF05642.6 ETO28685.1 - 4.1 5.1 9.8 1.9 6.2 5.5 1.3 2 0 0 2 2 2 0 Sporozoite P67 surface antigen SID-1_RNA_chan PF13965.1 ETO28685.1 - 5.4 5.0 8.6 0.86 7.6 3.3 1.5 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Metallophos_2 PF12850.2 ETO28686.1 - 1.9e-11 44.0 0.1 2.7e-11 43.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 ETO28686.1 - 1.9e-10 40.4 0.3 4.6e-10 39.2 0.2 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase BSP_II PF05432.6 ETO28686.1 - 0.015 14.5 1.2 0.025 13.8 0.8 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Thioredoxin PF00085.15 ETO28688.1 - 5e-65 215.7 0.0 7.7e-31 105.8 0.0 3.5 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.1 ETO28688.1 - 2e-33 115.7 0.2 3.2e-22 79.2 0.0 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 ETO28688.1 - 1e-16 61.1 1.8 8.7e-06 25.9 0.0 4.8 3 2 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_7 PF13899.1 ETO28688.1 - 9.8e-16 57.5 0.1 2.7e-06 27.2 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.1 ETO28688.1 - 6.3e-13 48.6 0.3 0.002 18.2 0.0 4.4 4 1 1 5 5 5 3 Thioredoxin-like AhpC-TSA PF00578.16 ETO28688.1 - 3.1e-08 33.3 0.4 0.0037 16.9 0.0 3.0 3 1 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.5 ETO28688.1 - 3.7e-05 23.2 0.1 0.062 12.8 0.0 2.7 2 0 0 2 2 2 2 Redoxin Thioredoxin_4 PF13462.1 ETO28688.1 - 0.0044 17.0 0.6 1.9 8.4 0.1 3.0 2 1 1 3 3 3 1 Thioredoxin Thioredoxin_3 PF13192.1 ETO28688.1 - 0.012 15.4 0.0 0.17 11.6 0.0 2.8 3 0 0 3 3 3 0 Thioredoxin domain TPM PF04536.9 ETO28688.1 - 0.085 12.7 0.0 0.29 11.0 0.0 1.8 1 0 0 1 1 1 0 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase DSBA PF01323.15 ETO28688.1 - 0.088 12.3 0.2 20 4.7 0.0 3.5 3 1 1 4 4 4 0 DSBA-like thioredoxin domain W2 PF02020.13 ETO28688.1 - 0.09 12.7 0.5 0.67 9.9 0.0 2.6 2 1 1 3 3 3 0 eIF4-gamma/eIF5/eIF2-epsilon DUF455 PF04305.9 ETO28689.1 - 3.3e-57 193.6 0.0 3.9e-57 193.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Motile_Sperm PF00635.21 ETO28691.1 - 0.0017 17.9 1.4 0.0056 16.2 0.1 2.6 3 0 0 3 3 3 1 MSP (Major sperm protein) domain CAMSAP_CH PF11971.3 ETO28691.1 - 0.0059 16.2 0.2 0.018 14.6 0.1 1.9 1 0 0 1 1 1 1 CAMSAP CH domain Golgin_A5 PF09787.4 ETO28691.1 - 2 6.8 11.4 0.083 11.3 2.3 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF2019 PF09450.5 ETO28692.1 - 0.087 12.6 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) Hom_end_hint PF05203.11 ETO28693.1 - 0.41 10.3 9.0 0.29 10.8 0.1 3.4 3 0 0 3 3 3 0 Hom_end-associated Hint ATG16 PF08614.6 ETO28694.1 - 0.0023 17.7 6.8 0.0023 17.7 4.7 3.3 3 0 0 3 3 3 1 Autophagy protein 16 (ATG16) DUF4446 PF14584.1 ETO28694.1 - 0.0044 16.8 0.3 0.0044 16.8 0.2 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF4446) Atg14 PF10186.4 ETO28694.1 - 0.031 13.2 23.6 0.2 10.5 0.1 3.1 3 0 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 TarH PF02203.10 ETO28694.1 - 0.049 13.4 0.2 0.049 13.4 0.1 1.9 2 0 0 2 2 2 0 Tar ligand binding domain homologue COG5 PF10392.4 ETO28694.1 - 0.19 11.6 6.6 0.26 11.2 0.1 3.1 3 0 0 3 3 3 0 Golgi transport complex subunit 5 Sad1_UNC PF07738.8 ETO28694.1 - 0.35 10.6 3.3 0.24 11.2 0.4 1.9 2 0 0 2 2 2 0 Sad1 / UNC-like C-terminal YjgP_YjgQ PF03739.9 ETO28694.1 - 0.78 8.4 5.7 3.3 6.3 3.9 2.0 1 1 0 1 1 1 0 Predicted permease YjgP/YjgQ family HR1 PF02185.11 ETO28694.1 - 2.1 8.1 22.0 3.1 7.6 4.0 4.4 4 1 0 4 4 4 0 Hr1 repeat IncA PF04156.9 ETO28694.1 - 2.3 7.7 24.4 1.1 8.8 4.0 3.0 2 1 0 3 3 3 0 IncA protein Bap31 PF05529.7 ETO28694.1 - 3.9 6.8 17.5 2.5 7.5 0.7 3.5 2 1 1 3 3 3 0 B-cell receptor-associated protein 31-like Rootletin PF15035.1 ETO28694.1 - 5.2 7.0 17.0 1.6 8.6 3.8 2.4 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion GrpE PF01025.14 ETO28694.1 - 8.8 5.8 17.2 0.049 13.1 1.1 3.1 2 1 0 2 2 2 0 GrpE SpoIISA_toxin PF14171.1 ETO28695.1 - 0.07 12.3 7.7 0.1 11.8 5.3 1.3 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system DUF4349 PF14257.1 ETO28695.1 - 0.074 12.2 1.6 0.13 11.4 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) SID-1_RNA_chan PF13965.1 ETO28695.1 - 0.075 11.1 3.7 0.085 11.0 2.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4335 PF14233.1 ETO28695.1 - 0.12 11.8 1.3 0.22 10.9 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) DUF413 PF04219.7 ETO28695.1 - 0.42 10.4 2.4 0.89 9.3 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function, DUF L31 PF09784.4 ETO28695.1 - 4.4 7.4 6.3 2.1 8.4 1.8 2.2 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L31 Pkinase PF00069.20 ETO28696.1 - 1.3e-06 27.8 2.9 2.1e-06 27.0 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO28696.1 - 0.002 17.2 0.0 0.024 13.7 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase DUF3306 PF11748.3 ETO28696.1 - 0.026 15.1 7.6 0.06 13.9 5.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Kdo PF06293.9 ETO28696.1 - 0.052 12.6 0.4 0.11 11.4 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Vma12 PF11712.3 ETO28696.1 - 0.58 9.8 3.9 1.6 8.4 2.7 1.7 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase PGA2 PF07543.7 ETO28696.1 - 1.4 8.7 14.4 0.28 10.9 7.5 1.6 2 0 0 2 2 2 0 Protein trafficking PGA2 Peptidase_S49_N PF08496.5 ETO28696.1 - 2.2 8.0 10.9 0.54 10.0 4.6 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Anoctamin PF04547.7 ETO28696.1 - 3.8 6.0 4.7 5.6 5.5 3.3 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel Vfa1 PF08432.5 ETO28696.1 - 5.4 7.0 21.2 0.87 9.5 11.6 1.9 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Pox_Ag35 PF03286.9 ETO28696.1 - 7.5 6.0 17.5 0.63 9.5 8.6 1.8 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF1510 PF07423.6 ETO28697.1 - 3.8e-06 26.4 4.8 4.6e-06 26.1 3.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) SpoIIIAH PF12685.2 ETO28697.1 - 0.00025 20.5 2.0 0.00029 20.4 1.4 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein EphA2_TM PF14575.1 ETO28697.1 - 0.00068 19.9 1.1 0.0011 19.3 0.7 1.4 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain FYDLN_acid PF09538.5 ETO28697.1 - 0.00073 20.0 8.4 0.00098 19.6 5.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) TMEM154 PF15102.1 ETO28697.1 - 0.0019 17.9 0.2 0.0024 17.5 0.1 1.2 1 0 0 1 1 1 1 TMEM154 protein family GRP PF07172.6 ETO28697.1 - 0.002 18.5 0.1 0.0028 18.1 0.1 1.1 1 0 0 1 1 1 1 Glycine rich protein family FAM176 PF14851.1 ETO28697.1 - 0.0049 16.5 0.3 0.0061 16.2 0.2 1.2 1 0 0 1 1 1 1 FAM176 family DUF2749 PF10907.3 ETO28697.1 - 0.0072 16.1 3.0 0.013 15.3 1.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2749) Sporozoite_P67 PF05642.6 ETO28697.1 - 0.0076 14.1 1.9 0.008 14.1 1.3 1.0 1 0 0 1 1 1 1 Sporozoite P67 surface antigen V_ATPase_I PF01496.14 ETO28697.1 - 0.012 13.5 0.0 0.012 13.5 0.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TRAP_alpha PF03896.11 ETO28697.1 - 0.017 14.1 7.0 0.02 13.8 4.8 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CobT PF06213.7 ETO28697.1 - 0.017 14.2 7.8 0.019 14.0 5.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Na_trans_assoc PF06512.8 ETO28697.1 - 0.019 14.9 1.2 0.023 14.7 0.8 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Protocadherin PF08374.6 ETO28697.1 - 0.021 14.4 0.0 0.023 14.3 0.0 1.1 1 0 0 1 1 1 0 Protocadherin SID-1_RNA_chan PF13965.1 ETO28697.1 - 0.037 12.2 0.0 0.042 12.0 0.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Baculo_11_kDa PF06143.6 ETO28697.1 - 0.076 12.3 0.5 0.11 11.8 0.3 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family SspB PF04386.8 ETO28697.1 - 0.079 12.5 1.3 0.12 11.9 0.9 1.2 1 0 0 1 1 1 0 Stringent starvation protein B DUF3357 PF11837.3 ETO28697.1 - 0.098 12.5 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Shisa PF13908.1 ETO28697.1 - 0.13 12.3 0.9 0.17 12.0 0.7 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Rhabdo_ncap PF00945.13 ETO28697.1 - 0.18 10.3 1.3 0.21 10.1 0.9 1.0 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Sigma70_ner PF04546.8 ETO28697.1 - 0.19 11.2 12.3 0.24 10.9 8.5 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region RRN3 PF05327.6 ETO28697.1 - 0.24 9.4 7.3 0.27 9.2 5.1 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.9 ETO28697.1 - 0.25 9.3 7.6 0.3 9.0 5.2 1.1 1 0 0 1 1 1 0 CDC45-like protein GCIP PF13324.1 ETO28697.1 - 0.51 9.5 6.3 0.61 9.2 4.4 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Tom22 PF04281.8 ETO28697.1 - 1.2 8.6 6.9 1.5 8.3 4.8 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DUF2457 PF10446.4 ETO28697.1 - 1.3 7.6 26.6 1.7 7.2 18.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Herpes_LMP1 PF05297.6 ETO28697.1 - 1.4 7.7 9.4 1.6 7.5 6.5 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Nucleoplasmin PF03066.10 ETO28697.1 - 1.5 8.3 14.8 2.5 7.6 10.3 1.4 1 0 0 1 1 1 0 Nucleoplasmin DUF1628 PF07790.6 ETO28697.1 - 2 9.2 9.5 2.9 8.7 6.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1628) Herpes_gE PF02480.11 ETO28697.1 - 3.2 5.9 7.9 5.7 5.0 5.4 1.3 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E HSP90 PF00183.13 ETO28697.1 - 3.3 5.9 6.6 3.9 5.7 4.5 1.0 1 0 0 1 1 1 0 Hsp90 protein DUF4637 PF15470.1 ETO28697.1 - 4.7 6.7 7.2 5.8 6.4 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) ANAPC15 PF15243.1 ETO28697.1 - 8.2 6.5 15.8 13 5.8 11.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 CENP-T PF15511.1 ETO28697.1 - 9.9 5.2 11.2 12 4.9 7.7 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF1736 PF08409.6 ETO28698.1 - 1.4e-23 82.2 0.9 1.4e-23 82.2 0.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1736) Med27 PF11571.3 ETO28699.1 - 0.2 11.7 4.3 0.14 12.2 0.4 2.8 2 2 2 4 4 4 0 Mediator complex subunit 27 RGM_C PF06534.8 ETO28700.1 - 0.05 12.7 0.2 0.063 12.4 0.1 1.1 1 0 0 1 1 1 0 Repulsive guidance molecule (RGM) C-terminus DUF3952 PF13130.1 ETO28700.1 - 0.063 13.2 6.0 0.18 11.8 4.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3952) OCIA PF07051.6 ETO28702.1 - 0.013 14.8 2.6 0.16 11.3 0.0 2.9 3 0 0 3 3 3 0 Ovarian carcinoma immunoreactive antigen (OCIA) TFIIF_alpha PF05793.7 ETO28702.1 - 1.1 7.4 23.5 0.06 11.7 9.0 2.4 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Tospo_nucleocap PF01533.11 ETO28703.1 - 0.01 15.0 2.3 0.016 14.4 1.6 1.2 1 0 0 1 1 1 0 Tospovirus nucleocapsid protein Flg_new PF09479.5 ETO28703.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) DUF1635 PF07795.6 ETO28703.1 - 0.69 9.2 6.4 4.1 6.7 4.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1635) MOZ_SAS PF01853.13 ETO28704.1 - 0.08 12.1 0.3 2.6 7.2 0.1 2.1 1 1 1 2 2 2 0 MOZ/SAS family MyTH4 PF00784.12 ETO28705.1 - 7e-27 93.6 0.2 4.9e-26 90.9 0.0 2.6 2 0 0 2 2 2 1 MyTH4 domain Ground-like PF04155.13 ETO28705.1 - 2 8.7 4.5 23 5.3 0.3 3.4 3 0 0 3 3 3 0 Ground-like domain ABC2_membrane_2 PF12679.2 ETO28706.1 - 0.016 14.1 0.0 0.018 13.8 0.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Band_3_cyto PF07565.8 ETO28706.1 - 0.35 10.3 11.8 0.62 9.5 8.2 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Serinc PF03348.10 ETO28706.1 - 2.7 6.6 4.6 3.6 6.1 3.2 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Zip PF02535.17 ETO28706.1 - 3.2 6.6 3.8 4.6 6.1 2.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Folate_carrier PF01770.13 ETO28706.1 - 7.5 4.9 5.4 12 4.2 3.8 1.2 1 0 0 1 1 1 0 Reduced folate carrier F-box-like PF12937.2 ETO28707.1 - 0.00081 19.0 0.1 0.0034 17.0 0.0 2.0 2 0 0 2 2 2 1 F-box-like DUF3271 PF11675.3 ETO28707.1 - 0.017 14.3 0.2 0.036 13.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3271) DUF2267 PF10025.4 ETO28707.1 - 0.022 14.7 0.0 0.56 10.2 0.0 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2267) Myosin_head PF00063.16 ETO28708.1 - 3.5e-101 339.3 3.7 8.6e-99 331.4 2.6 2.6 1 1 0 1 1 1 1 Myosin head (motor domain) AAA_5 PF07728.9 ETO28710.1 - 5.9e-05 22.8 0.0 0.00023 20.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 ETO28710.1 - 8.2e-05 22.8 0.1 0.00038 20.6 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 ETO28710.1 - 9.2e-05 22.3 1.1 0.00091 19.1 0.0 3.1 2 2 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 ETO28710.1 - 0.0011 18.5 0.1 0.0034 16.9 0.0 1.9 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF2087 PF09860.4 ETO28710.1 - 0.0039 16.8 0.2 0.01 15.5 0.2 1.8 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2087) AAA_17 PF13207.1 ETO28710.1 - 0.0061 17.3 0.0 0.12 13.1 0.0 3.1 2 2 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETO28710.1 - 0.013 15.6 0.1 0.41 10.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.9 ETO28710.1 - 0.018 14.9 1.6 0.065 13.1 0.0 2.6 4 0 0 4 4 4 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 ETO28710.1 - 0.019 14.1 0.2 0.79 8.8 0.0 2.3 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 ETO28710.1 - 0.045 14.0 0.3 0.16 12.2 0.0 2.1 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.7 ETO28710.1 - 0.045 13.4 3.5 0.25 10.9 0.0 3.4 4 0 0 4 4 4 0 NACHT domain AAA_22 PF13401.1 ETO28711.1 - 0.0038 17.3 0.0 0.04 14.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain KBP_C PF12309.3 ETO28712.1 - 0.01 14.8 4.2 0.013 14.5 2.9 1.1 1 0 0 1 1 1 0 KIF-1 binding protein C terminal CDC45 PF02724.9 ETO28712.1 - 0.065 11.2 7.1 0.08 10.9 4.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DRY_EERY PF09750.4 ETO28712.1 - 0.2 11.7 6.4 0.37 10.8 4.4 1.5 1 0 0 1 1 1 0 Alternative splicing regulator Zip PF02535.17 ETO28712.1 - 0.21 10.5 2.6 0.25 10.2 1.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Sporozoite_P67 PF05642.6 ETO28712.1 - 0.97 7.2 3.7 1.1 7.0 2.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4413 PF14372.1 ETO28713.1 - 0.02 14.8 0.7 0.081 12.9 0.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) V_ATPase_I PF01496.14 ETO28713.1 - 0.027 12.3 6.6 0.043 11.6 4.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cluap1 PF10234.4 ETO28713.1 - 0.034 13.3 8.8 0.054 12.6 6.1 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 Atg14 PF10186.4 ETO28713.1 - 0.19 10.6 8.8 0.35 9.7 6.1 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 ETO28713.1 - 0.7 8.4 19.4 0.29 9.7 11.7 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein APG6 PF04111.7 ETO28713.1 - 3.2 6.7 20.7 1.5 7.8 12.9 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF3552 PF12072.3 ETO28713.1 - 3.9 6.6 23.6 0.77 8.9 2.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) NPV_P10 PF05531.7 ETO28713.1 - 6 7.2 9.2 8.3 6.7 2.9 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.10 ETO28713.1 - 6.2 6.3 14.0 15 5.1 0.4 3.4 1 1 2 3 3 3 0 Septum formation initiator PDEase_I PF00233.14 ETO28714.1 - 3.7e-66 223.2 7.6 1.6e-37 129.5 4.3 2.3 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Ets PF00178.17 ETO28714.1 - 0.083 13.0 0.1 0.26 11.4 0.0 1.9 2 0 0 2 2 2 0 Ets-domain Menin PF05053.8 ETO28714.1 - 0.84 7.7 8.7 1.3 7.0 6.0 1.3 1 0 0 1 1 1 0 Menin DUF1335 PF07056.6 ETO28715.1 - 0.1 12.3 0.1 0.22 11.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1335) MIF4G PF02854.14 ETO28716.1 - 1.3e-22 80.2 0.5 1.3e-22 80.2 0.3 2.4 3 0 0 3 3 3 1 MIF4G domain MA3 PF02847.12 ETO28716.1 - 1.4e-11 44.0 0.3 1.4e-11 44.0 0.2 2.3 2 0 0 2 2 2 1 MA3 domain Hid1 PF12722.2 ETO28716.1 - 0.14 9.7 32.1 0.37 8.4 6.1 2.2 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Gon7 PF08738.5 ETO28717.1 - 0.018 15.0 0.3 0.032 14.2 0.2 1.4 1 0 0 1 1 1 0 Gon7 family PFEMP PF03011.10 ETO28717.1 - 0.032 14.5 1.5 0.032 14.5 1.1 2.2 2 0 0 2 2 2 0 PFEMP DBL domain NPV_P10 PF05531.7 ETO28717.1 - 0.054 13.7 0.2 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein HSBP1 PF06825.7 ETO28717.1 - 0.077 12.5 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Heat shock factor binding protein 1 TP2 PF01254.13 ETO28718.1 - 1.9 8.8 8.4 1.1 9.6 3.1 2.3 1 1 1 2 2 2 0 Nuclear transition protein 2 Acyl-CoA_dh_1 PF00441.19 ETO28719.1 - 5.1e-32 111.0 0.2 7.1e-32 110.5 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 ETO28719.1 - 2.6e-19 68.4 0.1 5.5e-19 67.4 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 ETO28719.1 - 1.2e-18 67.7 0.0 2.7e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 ETO28719.1 - 1.6e-10 41.3 0.0 2.4e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Ion_trans PF00520.26 ETO28721.1 - 3.6e-09 36.1 1.5 3.6e-09 36.1 1.0 1.5 2 0 0 2 2 2 1 Ion transport protein Folliculin PF11704.3 ETO28723.1 - 0.0091 15.5 6.3 0.044 13.3 4.3 2.1 1 1 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Allexi_40kDa PF05549.6 ETO28723.1 - 0.079 12.2 1.9 0.13 11.5 1.3 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein Neur_chan_memb PF02932.11 ETO28723.1 - 0.33 10.7 3.4 0.5 10.2 2.4 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RP-C_C PF11800.3 ETO28723.1 - 0.53 9.9 4.2 0.81 9.3 2.9 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region Hid1 PF12722.2 ETO28723.1 - 0.62 7.6 9.3 0.77 7.3 6.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Toprim PF01751.17 ETO28723.1 - 0.76 9.7 3.6 1.9 8.5 2.5 1.8 1 1 0 1 1 1 0 Toprim domain ALMT PF11744.3 ETO28723.1 - 1.3 7.5 4.7 1.9 7.0 3.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter ECH PF00378.15 ETO28727.1 - 1.4e-14 53.8 0.0 2.3e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family PUF PF00806.14 ETO28728.1 - 2.3e-38 127.5 11.4 4.4e-09 35.3 0.0 5.7 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat CENP-B_dimeris PF09026.5 ETO28728.1 - 0.016 15.3 8.1 0.016 15.3 5.6 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF1152 PF06626.7 ETO28728.1 - 0.033 13.2 0.0 0.065 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1152) Tautomerase PF01361.16 ETO28728.1 - 0.047 13.2 0.2 3.2 7.4 0.0 2.5 2 0 0 2 2 2 0 Tautomerase enzyme DUF1675 PF07897.6 ETO28728.1 - 0.21 11.3 11.5 0.31 10.8 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Nop14 PF04147.7 ETO28728.1 - 0.73 7.6 29.9 0.96 7.2 20.8 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.8 ETO28728.1 - 3.7 7.3 26.6 5.8 6.6 18.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NUDIX PF00293.23 ETO28729.1 - 4.8e-07 29.4 0.0 1.4e-06 28.0 0.0 1.8 1 1 0 1 1 1 1 NUDIX domain TPR_11 PF13414.1 ETO28730.1 - 2.7e-22 78.1 19.8 6.9e-05 22.4 0.7 5.6 4 2 2 6 6 6 6 TPR repeat TPR_8 PF13181.1 ETO28730.1 - 2.2e-17 61.4 17.6 0.011 15.4 0.3 7.5 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 ETO28730.1 - 2.1e-16 59.6 15.6 0.001 18.9 0.1 6.2 2 1 6 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.12 ETO28730.1 - 2e-14 52.2 19.6 0.0052 16.5 1.3 7.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO28730.1 - 1.3e-11 43.5 19.3 0.00032 20.1 1.0 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO28730.1 - 5.8e-11 42.0 0.4 0.33 11.6 0.0 6.4 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO28730.1 - 1.1e-08 35.5 0.4 0.98 10.1 0.0 4.9 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO28730.1 - 4.6e-08 33.2 5.7 0.07 13.4 0.0 4.9 3 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO28730.1 - 2e-06 27.8 2.4 0.038 14.4 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO28730.1 - 2.9e-06 26.6 9.6 0.64 9.9 0.2 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO28730.1 - 2.6e-05 24.0 22.3 0.098 12.9 0.1 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_15 PF13429.1 ETO28730.1 - 3.4e-05 23.0 0.1 0.043 12.8 0.1 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETO28730.1 - 0.00084 19.1 2.9 0.7 9.7 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO28730.1 - 0.0058 15.8 2.7 0.2 10.9 0.3 3.4 3 0 0 3 3 3 1 SHNi-TPR Sel1 PF08238.7 ETO28730.1 - 3.1 8.5 5.7 2.9 8.6 0.3 3.6 5 0 0 5 5 4 0 Sel1 repeat TPR_10 PF13374.1 ETO28730.1 - 5.6 7.0 8.9 27 4.8 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Exostosin PF03016.10 ETO28731.1 - 0.054 12.5 2.5 0.061 12.3 1.7 1.2 1 0 0 1 1 1 0 Exostosin family SR-25 PF10500.4 ETO28731.1 - 0.071 12.5 17.0 0.082 12.3 11.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Dict-STAT-coil PF09267.5 ETO28731.1 - 0.095 12.9 3.0 0.14 12.3 2.1 1.2 1 0 0 1 1 1 0 Dictyostelium STAT, coiled coil DUF3825 PF12873.2 ETO28731.1 - 0.11 11.6 5.7 0.14 11.3 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) DUF4569 PF15133.1 ETO28731.1 - 0.85 8.9 7.9 1 8.6 5.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) DUF4337 PF14235.1 ETO28731.1 - 0.91 9.3 6.5 1.2 8.9 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Arc_PepC_II PF06847.6 ETO28731.1 - 1 9.8 9.2 0.59 10.6 4.8 1.8 1 1 1 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II RAB3GAP2_N PF14655.1 ETO28732.1 - 5.8e-05 22.2 0.1 0.00013 21.1 0.0 1.5 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Sigma70_ner PF04546.8 ETO28732.1 - 0.11 12.1 4.0 3.7 7.1 0.1 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region CoA_binding_3 PF13727.1 ETO28733.1 - 0.0057 16.4 0.1 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 CoA-binding domain Med25_SD1 PF11235.3 ETO28734.1 - 0.082 13.2 8.2 0.19 12.0 5.7 1.5 1 0 0 1 1 1 0 Mediator complex subunit 25 synapsin 1 SRP54_N PF02881.14 ETO28735.1 - 0.11 12.5 0.9 0.26 11.4 0.4 1.8 1 1 1 2 2 2 0 SRP54-type protein, helical bundle domain SAM_1 PF00536.25 ETO28736.1 - 0.00027 21.0 0.0 0.00054 20.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO28736.1 - 0.001 18.8 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) MLANA PF14991.1 ETO28736.1 - 0.0031 17.5 0.0 0.0051 16.8 0.0 1.4 1 0 0 1 1 1 1 Protein melan-A TMEM154 PF15102.1 ETO28736.1 - 0.0065 16.1 2.2 0.0071 16.0 0.2 2.0 1 1 1 2 2 2 1 TMEM154 protein family Herpes_gE PF02480.11 ETO28736.1 - 0.0084 14.4 0.2 0.012 13.9 0.2 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Adeno_E3_CR2 PF02439.10 ETO28736.1 - 0.05 13.1 0.3 0.082 12.4 0.2 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 PIRT PF15099.1 ETO28736.1 - 0.079 12.1 0.1 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family TMEM51 PF15345.1 ETO28736.1 - 0.096 12.3 1.1 0.19 11.3 0.8 1.6 1 1 0 1 1 1 0 Transmembrane protein 51 CD34_antigen PF06365.7 ETO28736.1 - 0.12 12.0 1.1 0.17 11.4 0.0 1.7 2 1 0 2 2 2 0 CD34/Podocalyxin family Ank PF00023.25 ETO28737.1 - 2e-15 55.7 1.5 1.4e-10 40.4 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 ETO28737.1 - 4.7e-14 52.4 0.5 2.2e-13 50.3 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO28737.1 - 2.1e-11 42.9 2.5 8.8e-07 28.5 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 ETO28737.1 - 8.4e-11 42.0 1.5 1.4e-09 38.1 0.1 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO28737.1 - 2.3e-10 40.3 0.8 3e-08 33.6 0.1 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Synaptobrevin PF00957.16 ETO28738.1 - 0.0014 18.1 0.1 0.0033 16.9 0.0 1.7 2 0 0 2 2 2 1 Synaptobrevin Lipoprotein_19 PF13617.1 ETO28738.1 - 0.31 10.6 2.9 0.68 9.5 2.0 1.6 1 0 0 1 1 1 0 YnbE-like lipoprotein B9-C2 PF07162.6 ETO28739.1 - 1e-26 93.7 0.3 1.5e-26 93.1 0.2 1.3 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Secretin_N_2 PF07655.8 ETO28740.1 - 0.016 15.5 21.3 0.016 15.5 14.8 4.5 5 0 0 5 5 5 0 Secretin N-terminal domain Gly_transf_sug PF04488.10 ETO28741.1 - 2.2e-13 50.4 0.2 5.2e-13 49.2 0.1 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 ETO28741.1 - 0.0073 15.4 0.0 0.034 13.3 0.0 1.9 1 1 1 2 2 2 1 Capsular polysaccharide synthesis protein DUF3870 PF12986.2 ETO28742.1 - 0.1 12.8 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) Filament PF00038.16 ETO28743.1 - 0.0021 17.5 19.9 0.0021 17.5 13.8 4.5 4 1 1 5 5 5 2 Intermediate filament protein Reo_sigmaC PF04582.7 ETO28743.1 - 0.025 13.7 5.5 0.39 9.8 0.5 2.7 2 1 0 2 2 2 0 Reovirus sigma C capsid protein Cyc-maltodext_C PF10438.4 ETO28743.1 - 0.031 14.3 1.2 0.77 9.8 0.0 2.8 2 0 0 2 2 2 0 Cyclo-malto-dextrinase C-terminal domain DUF410 PF04190.8 ETO28744.1 - 1.2e-09 38.0 0.5 0.0017 17.9 0.0 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF410) DUF910 PF06014.6 ETO28744.1 - 0.12 12.2 1.1 2.1 8.3 0.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF910) SPRY PF00622.23 ETO28745.1 - 3.1e-07 30.5 0.0 0.00018 21.6 0.0 2.7 2 0 0 2 2 2 2 SPRY domain Secretin_N_2 PF07655.8 ETO28745.1 - 0.3 11.5 16.6 0.13 12.6 9.1 2.0 2 0 0 2 2 2 0 Secretin N-terminal domain Pex14_N PF04695.8 ETO28747.1 - 0.59 10.1 14.1 6.5 6.8 0.2 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Secretin_N_2 PF07655.8 ETO28747.1 - 5.6 7.4 41.6 0.24 11.8 4.0 2.9 3 0 0 3 3 3 0 Secretin N-terminal domain RhoGAP PF00620.22 ETO28748.1 - 4.1e-11 42.7 3.5 3.5e-10 39.6 0.0 2.9 2 1 0 2 2 2 1 RhoGAP domain PBP_sp32 PF07222.7 ETO28748.1 - 3.1 6.8 12.9 18 4.3 9.7 1.7 2 0 0 2 2 2 0 Proacrosin binding protein sp32 V_ATPase_I PF01496.14 ETO28748.1 - 3.4 5.4 7.8 5.4 4.7 5.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Glyco_transf_22 PF03901.12 ETO28749.1 - 3.7e-37 128.3 22.2 3.7e-37 128.3 15.4 2.2 2 1 0 2 2 2 1 Alg9-like mannosyltransferase family DUF2809 PF10990.3 ETO28749.1 - 8.4 6.8 12.2 0.9 9.9 2.4 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2809) Sulfatase PF00884.18 ETO28750.1 - 1.3e-41 142.7 0.6 4e-22 78.7 0.0 2.2 2 0 0 2 2 2 2 Sulfatase Phosphodiest PF01663.17 ETO28750.1 - 8.8e-06 25.2 0.0 0.0061 15.9 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Glyco_hydro_2_C PF02836.12 ETO28751.1 - 0.0062 15.4 0.4 0.035 13.0 0.1 2.4 1 1 1 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 ETO28752.1 - 2.3e-21 76.0 4.2 2.3e-21 76.0 2.9 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 ETO28752.1 - 7.6e-07 29.5 0.7 2.1e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 CARDB PF07705.6 ETO28752.1 - 0.04 13.9 1.2 0.27 11.2 0.0 2.3 2 1 0 2 2 2 0 CARDB DUF1183 PF06682.7 ETO28753.1 - 0.0026 17.4 0.6 0.004 16.8 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) Borrelia_rep PF03183.8 ETO28754.1 - 0.66 9.8 3.3 2 8.3 2.3 1.9 1 0 0 1 1 1 0 Borrelia repeat protein Phage_GP20 PF06810.6 ETO28755.1 - 0.0068 15.8 8.1 0.0068 15.8 5.6 2.3 2 1 0 2 2 2 1 Phage minor structural protein GP20 tRNA-synt_His PF13393.1 ETO28755.1 - 0.18 10.8 5.2 0.13 11.2 0.2 2.0 2 0 0 2 2 2 0 Histidyl-tRNA synthetase ALMT PF11744.3 ETO28755.1 - 0.2 10.2 10.7 0.79 8.3 1.3 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter DUF4633 PF15464.1 ETO28755.1 - 0.38 10.6 2.4 17 5.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4633) DUF445 PF04286.7 ETO28755.1 - 0.65 9.4 11.3 3.4 7.1 7.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF445) LUC7 PF03194.10 ETO28755.1 - 1.2 8.5 10.5 0.42 10.0 2.5 2.1 2 0 0 2 2 2 0 LUC7 N_terminus TMF_TATA_bd PF12325.3 ETO28755.1 - 1.3 8.8 10.5 0.19 11.4 3.4 2.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Flagellin_N PF00669.15 ETO28755.1 - 1.3 8.8 9.9 9.2 6.0 0.9 3.2 2 1 0 2 2 2 0 Bacterial flagellin N-terminal helical region ParB PF08775.5 ETO28755.1 - 3.8 7.8 9.7 6.2 7.1 2.4 2.7 2 1 1 3 3 3 0 ParB family DUF2408 PF10303.4 ETO28755.1 - 5.2 7.1 12.9 3 7.9 0.4 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Lge1 PF11488.3 ETO28755.1 - 6 7.1 11.5 5.4 7.2 0.8 3.1 2 1 1 3 3 3 0 Transcriptional regulatory protein LGE1 TALPID3 PF15324.1 ETO28755.1 - 6.4 3.9 12.1 3.5 4.8 0.6 2.0 2 0 0 2 2 2 0 Hedgehog signalling target FliD_N PF02465.13 ETO28755.1 - 6.8 7.1 10.5 0.22 11.9 0.9 2.4 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus LCAT PF02450.10 ETO28757.1 - 0.023 13.6 0.6 0.026 13.5 0.4 1.0 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Ribosomal_L18ae PF01775.12 ETO28757.1 - 0.059 13.2 3.8 0.081 12.8 2.6 1.5 1 1 0 1 1 1 0 Ribosomal L18ae/LX protein domain DUF4097 PF13349.1 ETO28757.1 - 0.38 10.2 6.7 0.47 9.9 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) BLVR PF06375.6 ETO28757.1 - 8.4 6.2 10.3 13 5.6 7.1 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) G-alpha PF00503.15 ETO28758.1 - 2.9e-11 42.6 2.2 7.3e-11 41.3 1.5 1.8 1 1 0 1 1 1 1 G-protein alpha subunit YcxB PF14317.1 ETO28760.1 - 0.023 13.9 1.0 0.61 9.3 0.1 2.5 2 0 0 2 2 2 0 YcxB-like protein GAGA_bind PF06217.7 ETO28760.1 - 0.66 9.8 5.8 0.91 9.4 4.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family TPR_12 PF13424.1 ETO28761.1 - 3.1e-41 139.1 7.8 8e-19 67.3 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO28761.1 - 2.6e-26 90.0 23.7 6.1e-08 31.9 1.1 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO28761.1 - 1.4e-25 88.7 16.3 9.1e-10 38.0 0.7 4.1 3 1 0 4 4 4 3 TPR repeat TPR_7 PF13176.1 ETO28761.1 - 1.6e-25 86.8 5.9 5.3e-06 25.8 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO28761.1 - 4.5e-25 86.7 0.0 0.00017 21.4 0.0 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO28761.1 - 1.7e-22 77.4 20.4 4.3e-06 26.2 0.6 6.0 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 ETO28761.1 - 2.5e-22 76.8 24.4 9.8e-08 31.2 2.1 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO28761.1 - 3.8e-08 33.7 0.0 0.08 13.6 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO28761.1 - 6.7e-08 32.1 10.5 0.18 12.0 0.8 5.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO28761.1 - 8.2e-07 29.1 0.0 2.4 9.0 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO28761.1 - 2.6e-06 27.5 5.1 0.14 12.7 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_3 PF07720.7 ETO28761.1 - 4.5e-05 23.1 14.9 0.014 15.1 0.9 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat MIT PF04212.13 ETO28761.1 - 0.00043 20.0 6.1 3.4 7.6 0.2 4.9 5 0 0 5 5 5 1 MIT (microtubule interacting and transport) domain DUF2225 PF09986.4 ETO28761.1 - 0.00081 18.9 13.0 0.051 13.0 0.6 3.4 1 1 2 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) SHNi-TPR PF10516.4 ETO28761.1 - 0.012 14.8 1.5 4.1 6.7 0.0 3.6 4 0 0 4 4 4 0 SHNi-TPR Apc3 PF12895.2 ETO28761.1 - 0.014 15.5 15.2 0.16 12.1 4.4 3.4 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DWNN PF08783.6 ETO28761.1 - 0.021 14.7 0.7 0.057 13.3 0.5 1.7 1 0 0 1 1 1 0 DWNN domain Fer4_12 PF13353.1 ETO28761.1 - 0.079 13.0 3.2 0.69 10.0 0.1 3.1 2 1 1 3 3 3 0 4Fe-4S single cluster domain PPR PF01535.15 ETO28761.1 - 0.09 12.7 7.6 8.2 6.6 0.0 4.9 5 0 0 5 5 4 0 PPR repeat TPR_19 PF14559.1 ETO28761.1 - 0.094 13.0 2.5 7 7.0 0.1 3.4 3 1 1 4 4 3 0 Tetratricopeptide repeat DUF627 PF04781.7 ETO28761.1 - 0.19 11.3 3.3 4 7.1 0.2 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF627) PPR_2 PF13041.1 ETO28761.1 - 3.9 7.5 6.6 13 5.8 0.0 4.1 5 0 0 5 5 4 0 PPR repeat family Exo_endo_phos PF03372.18 ETO28762.1 - 9.3e-08 32.3 0.0 1.6e-07 31.5 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1699 PF08004.6 ETO28762.1 - 0.0025 17.3 1.1 0.0051 16.3 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1699) SapB_1 PF05184.10 ETO28763.1 - 0.04 13.7 0.5 0.13 12.0 0.4 1.9 1 0 0 1 1 1 0 Saposin-like type B, region 1 RP-C_C PF11800.3 ETO28763.1 - 2.2 7.9 4.9 0.43 10.2 0.7 1.7 2 0 0 2 2 2 0 Replication protein C C-terminal region RNase_P_p30 PF01876.11 ETO28764.1 - 1.1e-11 44.1 3.2 2.3e-11 43.1 2.2 1.6 1 1 0 1 1 1 1 RNase P subunit p30 DUF3641 PF12345.3 ETO28764.1 - 0.16 11.8 0.2 0.16 11.8 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3641) Glycos_transf_1 PF00534.15 ETO28765.1 - 0.0082 15.5 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 ETO28766.1 - 1.5e-14 53.8 0.1 3.1e-14 52.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 ETO28766.1 - 3.2e-07 30.5 0.0 4.6e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 ETO28766.1 - 0.00016 21.8 0.0 0.0018 18.5 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Membr_traf_MHD PF10540.4 ETO28766.1 - 0.0032 17.2 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain YoaP PF14268.1 ETO28766.1 - 0.07 12.3 0.1 5.1 6.4 0.0 2.6 3 0 0 3 3 3 0 YoaP-like F-box-like_2 PF13013.1 ETO28767.1 - 0.046 13.4 0.1 0.14 11.9 0.1 1.8 1 0 0 1 1 1 0 F-box-like domain DDHD PF02862.12 ETO28768.1 - 0.031 14.0 4.7 0.059 13.1 3.3 1.4 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.9 ETO28769.1 - 0.68 7.8 4.4 0.78 7.6 3.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Taxilin PF09728.4 ETO28770.1 - 6.1e-13 48.5 30.0 9.5e-11 41.3 6.9 3.6 3 1 1 4 4 4 3 Myosin-like coiled-coil protein GAS PF13851.1 ETO28770.1 - 0.00086 18.5 45.9 0.042 13.0 19.2 3.1 2 2 0 2 2 2 2 Growth-arrest specific micro-tubule binding Myosin_tail_1 PF01576.14 ETO28770.1 - 0.0013 16.5 24.3 0.0013 16.5 16.9 2.4 3 0 0 3 3 3 2 Myosin tail ArabFuran-catal PF09206.6 ETO28771.1 - 0.0071 15.3 0.0 0.0096 14.9 0.0 1.1 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic CGGC PF08821.6 ETO28771.1 - 0.16 12.0 6.3 0.4 10.7 4.3 1.7 1 0 0 1 1 1 0 CGGC domain OAD_gamma PF04277.8 ETO28772.1 - 3.5 8.0 5.4 5.7 7.3 0.9 2.7 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain HsdM_N PF12161.3 ETO28772.1 - 9.8 6.6 13.2 22 5.4 5.2 2.7 2 1 0 2 2 2 0 HsdM N-terminal domain DPM2 PF07297.7 ETO28775.1 - 4.9e-07 29.9 0.7 6.2e-07 29.6 0.5 1.1 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF4526 PF15029.1 ETO28775.1 - 0.00092 18.8 0.3 0.00094 18.8 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4526) Tetraspannin PF00335.15 ETO28775.1 - 0.00095 18.5 2.3 0.0011 18.2 1.6 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF1240 PF06836.7 ETO28775.1 - 0.0079 16.3 1.4 0.011 15.9 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1240) zf-DHHC PF01529.15 ETO28775.1 - 0.012 14.9 1.6 0.014 14.8 1.1 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase MpPF26 PF07666.6 ETO28775.1 - 0.021 14.7 3.0 0.025 14.4 2.1 1.1 1 0 0 1 1 1 0 M penetrans paralogue family 26 AA_permease_2 PF13520.1 ETO28775.1 - 0.023 13.2 1.2 0.027 13.0 0.9 1.1 1 0 0 1 1 1 0 Amino acid permease Claudin_2 PF13903.1 ETO28775.1 - 0.055 13.1 0.3 0.067 12.8 0.2 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Neurensin PF14927.1 ETO28775.1 - 0.1 11.9 0.7 0.62 9.4 0.0 2.0 1 1 1 2 2 2 0 Neurensin NVEALA PF14055.1 ETO28775.1 - 0.18 11.5 1.3 0.72 9.5 0.5 2.0 2 0 0 2 2 2 0 NVEALA protein RSN1_TM PF13967.1 ETO28775.1 - 0.3 10.6 2.4 0.59 9.6 1.6 1.5 1 1 0 1 1 1 0 Late exocytosis, associated with Golgi transport RRM_4 PF10598.4 ETO28775.1 - 0.43 10.4 3.9 0.31 10.9 0.1 2.0 1 1 1 2 2 2 0 RNA recognition motif of the spliceosomal PrP8 DUF1211 PF06736.6 ETO28775.1 - 0.5 10.5 2.7 0.79 9.9 1.7 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1211) BPD_transp_1 PF00528.17 ETO28775.1 - 0.61 9.5 3.8 0.71 9.3 2.6 1.1 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component DUF1600 PF07667.6 ETO28775.1 - 7.4 6.7 7.9 35 4.5 5.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1600) WD40 PF00400.27 ETO28776.1 - 4e-25 86.7 12.3 5.1e-12 45.1 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 ETO28776.1 - 0.008 15.9 0.4 0.31 10.7 0.0 2.6 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO28776.1 - 0.015 13.4 0.6 0.33 9.0 0.1 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 PD40 PF07676.7 ETO28776.1 - 0.02 14.5 0.2 0.059 13.0 0.1 1.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat BBS2_Mid PF14783.1 ETO28776.1 - 0.067 12.9 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region Peptidase_M1 PF01433.15 ETO28778.1 - 2.2e-44 152.1 0.0 2.6e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M1 WD40 PF00400.27 ETO28779.1 - 5.6e-82 266.9 22.6 1.7e-13 49.9 0.3 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO28779.1 - 1.9e-08 34.2 1.8 0.0053 16.4 0.1 3.0 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO28779.1 - 3.3e-08 32.1 13.3 0.011 13.9 0.6 5.1 1 1 5 6 6 6 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO28779.1 - 6.6e-08 31.2 0.3 0.00078 17.8 0.0 2.8 1 1 2 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO28779.1 - 0.00017 20.5 14.1 0.47 9.1 0.6 5.5 1 1 1 3 3 3 2 Nup133 N terminal like PD40 PF07676.7 ETO28779.1 - 0.00036 20.1 10.5 1.3 8.7 0.1 5.4 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO28779.1 - 0.00036 20.7 2.1 6.2 7.1 0.0 4.4 2 2 3 5 5 5 1 Resistin Str_synth PF03088.11 ETO28779.1 - 0.0047 16.9 0.7 5.7 7.0 0.0 4.4 2 2 3 5 5 5 1 Strictosidine synthase DUF4275 PF14101.1 ETO28779.1 - 0.015 15.3 0.0 0.65 10.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4275) GATase PF00117.23 ETO28779.1 - 0.022 14.1 0.0 4 6.8 0.0 3.1 1 1 1 3 3 3 0 Glutamine amidotransferase class-I Nbas_N PF15492.1 ETO28779.1 - 0.034 13.2 1.8 5.8 5.9 0.1 3.7 1 1 4 5 5 5 0 Neuroblastoma-amplified sequence, N terminal PI-PLC-Y PF00387.14 ETO28779.1 - 0.062 13.2 0.0 0.24 11.4 0.0 2.0 2 0 0 2 2 2 0 Phosphatidylinositol-specific phospholipase C, Y domain Coatomer_WDAD PF04053.9 ETO28779.1 - 0.075 11.8 4.4 0.16 10.7 1.0 2.5 1 1 1 2 2 2 0 Coatomer WD associated region Kelch_1 PF01344.20 ETO28780.1 - 9.1e-07 28.3 6.7 0.0025 17.3 0.3 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO28780.1 - 1.2e-05 25.2 6.5 0.00067 19.7 0.1 3.5 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO28780.1 - 5.2e-05 22.9 1.2 0.00092 18.9 0.1 3.0 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO28780.1 - 8.2e-05 22.2 1.3 0.26 11.1 0.1 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 ETO28780.1 - 0.00032 20.7 0.0 0.0045 17.1 0.0 2.6 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO28780.1 - 0.003 17.4 2.2 0.18 11.8 0.8 2.7 2 0 0 2 2 2 1 Kelch motif DUF4463 PF14703.1 ETO28781.1 - 0.013 16.0 4.3 0.013 16.0 3.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4463) Sigma70_ner PF04546.8 ETO28782.1 - 0.17 11.4 9.2 0.094 12.3 1.5 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region RXT2_N PF08595.6 ETO28782.1 - 0.3 10.8 14.0 0.73 9.6 5.5 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal CDC45 PF02724.9 ETO28782.1 - 2.3 6.1 10.4 0.42 8.5 3.4 1.9 2 0 0 2 2 2 0 CDC45-like protein DUF4551 PF15087.1 ETO28782.1 - 6 5.1 8.9 7.6 4.7 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Tom37_C PF11801.3 ETO28782.1 - 9.2 6.0 9.6 0.86 9.4 1.0 2.1 2 0 0 2 2 2 0 Tom37 C-terminal domain WD40 PF00400.27 ETO28784.1 - 1.2e-40 135.9 13.3 1.2e-10 40.7 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat zf-TRAF PF02176.13 ETO28784.1 - 0.0036 17.6 5.1 0.0036 17.6 3.5 2.5 2 1 0 2 2 2 1 TRAF-type zinc finger Myb_DNA-bind_3 PF12776.2 ETO28784.1 - 0.043 14.4 1.5 0.14 12.8 1.0 1.9 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF2674 PF10879.3 ETO28784.1 - 0.058 13.1 0.9 0.24 11.1 0.6 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2674) Stathmin PF00836.14 ETO28784.1 - 0.062 12.9 9.1 0.14 11.8 6.3 1.5 1 0 0 1 1 1 0 Stathmin family Striatin PF08232.7 ETO28784.1 - 0.075 13.3 3.4 0.15 12.3 2.3 1.4 1 0 0 1 1 1 0 Striatin family Kinesin-relat_1 PF12711.2 ETO28784.1 - 0.76 10.2 7.9 3.8 7.9 5.5 2.1 1 1 0 1 1 1 0 Kinesin motor TPR_MLP1_2 PF07926.7 ETO28784.1 - 0.99 9.1 11.2 0.22 11.2 5.3 1.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF724 PF05266.9 ETO28784.1 - 1 8.9 9.7 0.39 10.3 4.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF724) CENP-Q PF13094.1 ETO28784.1 - 3.6 7.5 8.9 3.3 7.7 4.4 1.9 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit bZIP_1 PF00170.16 ETO28784.1 - 5.3 7.0 12.2 0.08 12.9 2.9 2.2 2 1 0 2 2 1 0 bZIP transcription factor NosD PF05048.8 ETO28787.1 - 0.00043 19.5 1.6 0.00076 18.7 1.1 1.3 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) MIF4G PF02854.14 ETO28788.1 - 4.1e-08 32.8 1.1 3e-07 30.0 0.7 1.9 1 1 0 1 1 1 1 MIF4G domain tRNA-synt_1 PF00133.17 ETO28789.1 - 2.1e-147 491.7 0.0 1.9e-146 488.5 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 ETO28789.1 - 1.2e-11 43.8 0.3 1.5e-07 30.4 0.0 3.1 2 1 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 ETO28789.1 - 3.6e-11 42.7 0.0 3.6e-09 36.1 0.0 2.3 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1d PF00750.14 ETO28789.1 - 0.013 14.3 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (R) Jag_N PF14804.1 ETO28789.1 - 0.059 13.3 1.8 0.077 13.0 0.0 2.2 3 0 0 3 3 3 0 Jag N-terminus tRNA-synt_1c PF00749.16 ETO28789.1 - 0.09 11.4 0.5 3 6.4 0.1 2.2 1 1 1 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain FlaC_arch PF05377.6 ETO28790.1 - 0.06 13.2 0.1 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Pox_A_type_inc PF04508.7 ETO28790.1 - 0.083 12.7 0.2 0.32 10.9 0.1 2.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Sec2p PF06428.6 ETO28790.1 - 0.17 11.7 4.1 0.076 12.8 1.0 1.8 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Serine_rich PF08824.5 ETO28790.1 - 0.54 9.9 3.0 0.31 10.7 0.7 1.6 2 0 0 2 2 2 0 Serine rich protein interaction domain Fijivirus_P9-2 PF06837.6 ETO28790.1 - 0.65 9.1 3.1 3.5 6.6 0.2 2.4 2 1 0 2 2 2 0 Fijivirus P9-2 protein Anticodon_1 PF08264.8 ETO28791.1 - 8e-35 119.8 0.1 1.4e-34 119.0 0.1 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1 PF00133.17 ETO28791.1 - 9.4e-07 27.2 0.0 1.3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) M11L PF11099.3 ETO28792.1 - 0.065 12.9 0.1 0.097 12.4 0.1 1.2 1 0 0 1 1 1 0 Apoptosis regulator M11L like TPT PF03151.11 ETO28793.1 - 5.7e-09 35.8 1.9 5.7e-09 35.8 1.3 2.5 3 0 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 ETO28793.1 - 0.00019 21.4 1.5 0.00019 21.4 1.1 2.3 2 0 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 ETO28793.1 - 0.00028 21.0 1.9 0.00028 21.0 1.3 2.7 3 0 0 3 3 3 1 Multidrug resistance efflux transporter DUF2899 PF11449.3 ETO28793.1 - 0.02 14.1 1.6 0.029 13.5 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2899) COX14 PF14880.1 ETO28793.1 - 0.033 13.7 1.6 0.6 9.7 0.1 2.6 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Bromo_TP PF07524.8 ETO28794.1 - 2.6e-12 46.2 0.1 4.1e-12 45.6 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.4 ETO28794.1 - 3.2e-05 23.8 1.4 0.00011 22.1 0.9 2.0 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term CBFD_NFYB_HMF PF00808.18 ETO28794.1 - 9e-05 22.4 0.1 0.00063 19.7 0.0 2.4 2 1 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 ETO28794.1 - 0.005 16.9 0.0 0.0097 16.0 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 ETO28794.1 - 0.03 14.2 0.0 0.079 12.9 0.0 1.8 1 1 0 1 1 1 0 TATA box binding protein associated factor (TAF) PB1-F2 PF11986.3 ETO28796.1 - 0.27 11.2 2.2 0.54 10.3 1.5 1.5 1 0 0 1 1 1 0 Influenza A Proapoptotic protein DUF4463 PF14703.1 ETO28798.1 - 0.0046 17.4 5.5 0.39 11.2 3.1 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4463) Tctex-1 PF03645.8 ETO28798.1 - 0.056 13.2 0.4 0.38 10.6 0.3 2.2 1 1 0 1 1 1 0 Tctex-1 family MIT PF04212.13 ETO28798.1 - 0.099 12.5 0.0 1.4 8.8 0.1 2.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain SGL PF08450.7 ETO28798.1 - 0.12 11.6 0.0 0.17 11.2 0.0 1.3 1 1 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region Formyl_trans_C PF02911.13 ETO28800.1 - 0.023 14.7 0.0 0.039 14.0 0.0 1.3 1 0 0 1 1 1 0 Formyl transferase, C-terminal domain Lactamase_B_5 PF14597.1 ETO28800.1 - 0.063 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily ABC2_membrane PF01061.19 ETO28801.1 - 7.8e-34 116.6 20.3 7.8e-34 116.6 14.1 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 ETO28801.1 - 7.3e-05 21.9 25.9 0.00024 20.2 18.0 1.8 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.2 ETO28801.1 - 8.3 5.1 21.3 1.8 7.3 9.7 2.2 1 1 1 2 2 2 0 ABC-2 family transporter protein RRM_1 PF00076.17 ETO28802.1 - 2.4e-05 23.8 0.0 5.9e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO28802.1 - 0.00062 19.6 0.0 0.0037 17.2 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Daxx PF03344.10 ETO28802.1 - 0.053 12.0 30.3 0.068 11.6 21.0 1.1 1 0 0 1 1 1 0 Daxx Family DUF1387 PF07139.6 ETO28802.1 - 8.9 5.8 34.5 1.8 8.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) MIB_HERC2 PF06701.8 ETO28803.1 - 1.1e-29 102.1 19.8 8.2e-19 67.3 3.5 4.5 4 0 0 4 4 4 3 Mib_herc2 RasGEF_N PF00618.15 ETO28805.1 - 8.2e-05 22.6 0.1 8.2e-05 22.6 0.1 4.4 5 1 0 5 5 5 1 RasGEF N-terminal motif Daxx PF03344.10 ETO28806.1 - 2.5e-06 26.2 29.8 2.9e-06 26.1 20.7 1.2 1 0 0 1 1 1 1 Daxx Family Utp14 PF04615.8 ETO28806.1 - 0.00042 18.6 41.7 0.00054 18.2 28.9 1.1 1 0 0 1 1 1 1 Utp14 protein YL1 PF05764.8 ETO28806.1 - 0.04 13.5 50.1 0.057 13.0 34.7 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DUF2890 PF11081.3 ETO28806.1 - 0.055 13.5 21.8 0.081 12.9 15.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF2413 PF10310.4 ETO28806.1 - 0.077 11.7 31.8 0.093 11.5 22.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) SOBP PF15279.1 ETO28806.1 - 0.6 10.4 18.6 0.97 9.7 12.9 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein LMBR1 PF04791.11 ETO28806.1 - 1.3 7.4 13.9 1.7 7.1 9.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Ebola_NP PF05505.7 ETO28806.1 - 1.8 6.5 22.5 1.9 6.4 15.6 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein CENP-T PF15511.1 ETO28806.1 - 1.9 7.6 21.4 2.4 7.2 14.8 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Ycf1 PF05758.7 ETO28806.1 - 2.1 5.9 32.9 2.9 5.4 22.8 1.2 1 0 0 1 1 1 0 Ycf1 RNA_pol_Rpb1_5 PF04998.12 ETO28806.1 - 7.4 5.7 24.8 0.67 9.1 13.0 1.9 1 1 1 2 2 2 0 RNA polymerase Rpb1, domain 5 SET PF00856.23 ETO28807.1 - 3.3e-17 63.2 4.5 1.2e-16 61.4 0.1 2.9 2 1 0 2 2 2 1 SET domain CDC45 PF02724.9 ETO28807.1 - 0.025 12.6 5.4 0.027 12.5 3.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 ETO28807.1 - 0.28 9.0 17.5 0.37 8.6 12.1 1.1 1 0 0 1 1 1 0 Nop14-like family Raftlin PF15250.1 ETO28807.1 - 0.86 8.0 7.5 1.2 7.5 5.2 1.1 1 0 0 1 1 1 0 Raftlin Herpes_LMP1 PF05297.6 ETO28807.1 - 1.1 8.0 8.9 1.4 7.7 6.2 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Sigma70_ner PF04546.8 ETO28807.1 - 1.6 8.3 9.8 2.7 7.5 6.8 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Retinal PF15449.1 ETO28807.1 - 1.8 6.1 6.7 2.2 5.7 4.6 1.1 1 0 0 1 1 1 0 Retinal protein Sporozoite_P67 PF05642.6 ETO28807.1 - 5.1 4.8 10.8 7.4 4.2 7.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2457 PF10446.4 ETO28807.1 - 5.7 5.5 18.2 8.6 4.9 12.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF4407 PF14362.1 ETO28807.1 - 6.9 5.5 6.4 9.7 5.0 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PAN_4 PF14295.1 ETO28809.1 - 0.012 15.3 1.2 0.044 13.4 0.8 1.9 1 0 0 1 1 1 0 PAN domain ERF PF04404.7 ETO28809.1 - 0.023 14.2 1.9 0.052 13.0 1.3 1.6 1 0 0 1 1 1 0 ERF superfamily Sep15_SelM PF08806.6 ETO28809.1 - 0.13 12.0 1.9 6.5 6.5 0.0 2.9 3 0 0 3 3 3 0 Sep15/SelM redox domain Methyltransf_11 PF08241.7 ETO28810.1 - 7.2e-05 23.2 0.1 0.00024 21.5 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO28810.1 - 0.00052 20.4 0.1 0.0013 19.1 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETO28810.1 - 0.007 15.4 0.0 0.016 14.3 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Cytochrom_B562 PF07361.6 ETO28811.1 - 0.11 12.9 1.3 0.18 12.1 0.9 1.4 1 0 0 1 1 1 0 Cytochrome b562 RP-C_C PF11800.3 ETO28811.1 - 0.18 11.5 2.1 0.12 12.0 0.4 1.5 2 0 0 2 2 2 0 Replication protein C C-terminal region WD40 PF00400.27 ETO28813.1 - 3.4e-95 308.8 27.4 2.2e-10 40.0 0.0 15.4 17 0 0 17 17 17 12 WD domain, G-beta repeat Pentapeptide PF00805.17 ETO28813.1 - 3.1e-06 26.2 3.7 8.1e-06 24.9 2.5 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) PQQ_2 PF13360.1 ETO28813.1 - 8.3e-06 25.4 0.0 0.016 14.6 0.0 3.9 1 1 1 2 2 2 2 PQQ-like domain Pentapeptide_4 PF13599.1 ETO28813.1 - 7.8e-05 22.4 0.5 0.00019 21.1 0.3 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) PD40 PF07676.7 ETO28813.1 - 0.00031 20.3 16.9 1.2 8.8 0.1 9.5 11 0 0 11 11 11 1 WD40-like Beta Propeller Repeat NACHT PF05729.7 ETO28813.1 - 0.014 15.0 0.0 0.057 13.0 0.0 2.0 1 1 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 ETO28813.1 - 0.019 14.8 4.9 0.13 12.1 0.4 3.3 2 0 0 2 2 2 0 AAA domain Pentapeptide_3 PF13576.1 ETO28813.1 - 0.024 14.5 5.3 0.048 13.5 2.8 2.2 2 1 1 3 3 3 0 Pentapeptide repeats (9 copies) HELP PF03451.9 ETO28814.1 - 0.037 13.5 0.0 0.09 12.3 0.0 1.6 1 0 0 1 1 1 0 HELP motif RGS PF00615.14 ETO28815.1 - 0.00052 20.1 2.8 0.003 17.6 1.9 2.3 1 1 0 1 1 1 1 Regulator of G protein signaling domain PapC_N PF13954.1 ETO28816.1 - 0.054 13.0 0.1 0.11 12.1 0.1 1.5 1 1 0 1 1 1 0 PapC N-terminal domain RPEL PF02755.10 ETO28817.1 - 0.00014 21.0 10.0 0.0002 20.5 0.1 4.4 5 0 0 5 5 5 2 RPEL repeat Herpes_LMP1 PF05297.6 ETO28817.1 - 0.65 8.8 3.2 0.85 8.4 2.2 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Sporozoite_P67 PF05642.6 ETO28817.1 - 0.99 7.1 13.9 1.9 6.2 9.6 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen WD40 PF00400.27 ETO28818.1 - 5.9e-123 396.8 47.1 6.7e-12 44.7 1.0 14.0 14 0 0 14 14 14 12 WD domain, G-beta repeat eIF2A PF08662.6 ETO28818.1 - 1.3e-24 86.9 0.1 8e-05 22.4 0.0 6.4 1 1 4 6 6 6 5 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO28818.1 - 9.5e-10 37.3 1.9 0.0051 15.1 0.0 4.5 3 2 1 4 4 4 3 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO28818.1 - 3.8e-08 32.5 25.5 0.013 14.2 1.4 6.2 1 1 4 5 5 5 4 Nup133 N terminal like Pentapeptide PF00805.17 ETO28818.1 - 2.1e-07 30.0 3.6 4.7e-07 28.8 2.5 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO28818.1 - 7.7e-05 22.4 1.4 0.00014 21.6 0.1 2.1 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) DUF1258 PF06869.7 ETO28818.1 - 0.00017 20.8 2.5 1.2 8.1 0.1 3.9 3 1 1 4 4 4 3 Protein of unknown function (DUF1258) Pentapeptide_3 PF13576.1 ETO28818.1 - 0.00052 19.8 3.3 0.00081 19.2 0.3 2.4 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) PD40 PF07676.7 ETO28818.1 - 0.066 12.9 12.7 8.7 6.1 0.0 7.5 9 0 0 9 9 9 0 WD40-like Beta Propeller Repeat DUF3677 PF12432.3 ETO28818.1 - 0.077 13.4 0.1 0.88 10.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3677) Hira PF07569.6 ETO28818.1 - 0.11 11.6 8.3 4.6 6.3 0.0 6.0 5 2 1 7 7 7 0 TUP1-like enhancer of split NACHT PF05729.7 ETO28819.1 - 4.6e-11 42.6 0.0 1.3e-10 41.1 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.1 ETO28819.1 - 3.9e-05 23.9 2.5 0.0025 18.0 0.0 3.8 3 0 0 3 3 3 1 AAA domain RelA_SpoT PF04607.12 ETO28819.1 - 0.00049 20.0 0.3 0.0018 18.2 0.2 2.0 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins AAA_22 PF13401.1 ETO28819.1 - 0.001 19.2 0.0 0.0077 16.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ETO28819.1 - 0.0088 16.8 0.3 0.069 13.9 0.0 2.7 3 1 0 3 3 3 1 AAA domain UPF0079 PF02367.12 ETO28819.1 - 0.015 14.9 0.0 0.14 11.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 ETO28819.1 - 0.019 14.9 0.0 0.098 12.6 0.0 2.2 1 1 1 2 2 2 0 AAA ATPase domain AAA PF00004.24 ETO28819.1 - 0.029 14.5 0.2 0.25 11.5 0.0 2.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 ETO28819.1 - 0.063 13.1 0.0 0.28 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 ETO28819.1 - 0.077 12.7 0.1 0.81 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) CUE PF02845.11 ETO28819.1 - 0.23 10.9 0.1 0.23 10.9 0.1 2.6 4 0 0 4 4 4 0 CUE domain PA26 PF04636.8 ETO28820.1 - 4.6e-28 98.1 0.1 4.6e-28 98.1 0.1 2.0 2 0 0 2 2 2 1 PA26 p53-induced protein (sestrin) PA26 PF04636.8 ETO28821.1 - 4.3e-10 38.8 0.5 5.7e-10 38.4 0.4 1.1 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) HNH_2 PF13391.1 ETO28822.1 - 0.043 13.5 0.0 5.9 6.7 0.0 2.3 2 1 0 2 2 2 0 HNH endonuclease RQC PF09382.5 ETO28823.1 - 6.7e-05 22.5 0.0 0.00024 20.7 0.0 2.0 2 0 0 2 2 2 1 RQC domain GOLD_2 PF13897.1 ETO28823.1 - 6.6 6.9 10.6 1.6 8.9 1.8 2.5 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking PGM_PMM_I PF02878.11 ETO28824.1 - 8.9e-15 54.3 0.1 1e-07 31.5 0.1 3.6 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 ETO28824.1 - 4.1e-09 36.6 0.0 1.6e-08 34.8 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 ETO28824.1 - 4.2e-05 23.5 0.0 0.00012 22.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Bac_export_2 PF01312.14 ETO28824.1 - 1.8 7.3 6.7 0.82 8.5 0.1 2.1 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family Glyco_trans_2_3 PF13632.1 ETO28824.1 - 9.3 5.9 9.0 22 4.6 6.3 1.6 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Surfac_D-trimer PF09006.6 ETO28825.1 - 0.014 15.1 0.0 0.31 10.8 0.0 2.8 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation DNA_pol3_beta_2 PF02767.11 ETO28825.1 - 0.073 13.1 0.0 0.37 10.8 0.0 2.2 3 0 0 3 3 3 0 DNA polymerase III beta subunit, central domain SR-25 PF10500.4 ETO28825.1 - 2.8 7.3 13.1 5 6.5 2.6 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TCO89 PF10452.4 ETO28827.1 - 0.028 13.3 0.5 0.029 13.2 0.3 1.1 1 0 0 1 1 1 0 TORC1 subunit TCO89 Cmyb_C PF09316.5 ETO28827.1 - 0.061 12.9 1.6 0.067 12.8 1.1 1.1 1 0 0 1 1 1 0 C-myb, C-terminal Ank_2 PF12796.2 ETO28828.1 - 5.1e-42 142.1 0.0 1.2e-18 67.2 0.0 2.5 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO28828.1 - 5.6e-26 90.4 0.2 7.3e-12 45.4 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 ETO28828.1 - 8.1e-23 79.0 0.0 3.2e-08 32.9 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 ETO28828.1 - 8.1e-18 64.0 5.7 1.6e-07 31.3 0.0 4.5 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO28828.1 - 7.1e-17 59.8 0.1 7.2e-05 22.6 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat DUF3413 PF11893.3 ETO28828.1 - 0.081 11.8 2.4 0.13 11.1 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) Arginase PF00491.16 ETO28832.1 - 7e-31 107.5 0.0 1.6e-29 103.1 0.0 2.1 1 1 0 1 1 1 1 Arginase family CitMHS PF03600.11 ETO28833.1 - 0.0002 20.0 0.0 0.00065 18.3 0.0 1.7 1 1 1 2 2 2 1 Citrate transporter LMF1 PF06762.9 ETO28835.1 - 1.1e-20 73.8 3.1 3.2e-10 39.3 0.1 2.8 2 1 0 2 2 2 2 Lipase maturation factor DUF3566 PF12089.3 ETO28835.1 - 1.7 8.6 4.8 0.64 10.0 0.3 2.2 1 1 1 2 2 2 0 Transmembrane domain of unknown function (DUF3566) TBCA PF02970.11 ETO28836.1 - 0.027 14.5 0.4 0.048 13.7 0.3 1.4 1 0 0 1 1 1 0 Tubulin binding cofactor A RhoGAP PF00620.22 ETO28837.1 - 6e-23 81.1 0.0 1.2e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.18 ETO28837.1 - 4.2e-14 53.0 0.2 3.5e-12 46.7 0.1 2.6 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DUF3211 PF11485.3 ETO28837.1 - 0.011 15.7 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3211) VHP PF02209.14 ETO28837.1 - 0.19 11.4 3.2 0.55 9.9 1.3 2.4 2 0 0 2 2 2 0 Villin headpiece domain Intimin_C PF07979.6 ETO28837.1 - 0.31 11.2 2.1 13 6.0 0.3 2.5 2 0 0 2 2 2 0 Intimin C-type lectin domain PH PF00169.24 ETO28838.1 - 0.00011 22.4 0.2 0.00055 20.1 0.1 2.3 1 1 0 1 1 1 1 PH domain PH_8 PF15409.1 ETO28838.1 - 0.001 19.0 0.2 0.0043 17.1 0.1 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain XAP5 PF04921.9 ETO28838.1 - 0.53 9.8 17.9 1 8.8 12.4 1.5 1 0 0 1 1 1 0 XAP5, circadian clock regulator Utp14 PF04615.8 ETO28838.1 - 0.8 7.8 32.0 1.1 7.3 22.2 1.1 1 0 0 1 1 1 0 Utp14 protein PH_11 PF15413.1 ETO28838.1 - 1.5 9.0 7.0 2.1 8.6 0.1 3.2 2 2 1 3 3 3 0 Pleckstrin homology domain Zip PF02535.17 ETO28838.1 - 8.2 5.3 7.6 13 4.6 5.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter tRNA-synt_1 PF00133.17 ETO28839.1 - 9.2e-171 568.8 5.5 1.6e-170 568.0 0.0 2.9 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 ETO28839.1 - 8.2e-33 113.3 0.1 8.2e-33 113.3 0.1 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.1 ETO28839.1 - 5e-11 42.2 0.0 5e-11 42.2 0.0 3.2 2 2 1 3 3 3 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 ETO28839.1 - 8.2e-11 41.1 9.8 1.2e-06 27.5 0.0 4.6 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1d PF00750.14 ETO28839.1 - 0.0022 16.8 6.8 0.024 13.4 0.0 3.1 3 0 0 3 3 3 1 tRNA synthetases class I (R) CDC45 PF02724.9 ETO28839.1 - 0.13 10.3 10.4 0.3 9.0 7.2 1.5 1 0 0 1 1 1 0 CDC45-like protein Rtf2 PF04641.7 ETO28839.1 - 0.13 11.3 20.2 0.23 10.6 14.0 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Hom_end_hint PF05203.11 ETO28839.1 - 0.62 9.7 10.1 6.9 6.3 6.0 2.2 2 0 0 2 2 2 0 Hom_end-associated Hint DUF106 PF01956.11 ETO28839.1 - 3.3 7.2 9.2 7.2 6.1 6.4 1.5 1 0 0 1 1 1 0 Integral membrane protein DUF106 FAM176 PF14851.1 ETO28839.1 - 3.9 7.1 10.0 11 5.6 6.7 1.9 1 1 0 1 1 1 0 FAM176 family LigT_PEase PF02834.11 ETO28840.1 - 1.8e-08 34.2 0.2 2.1e-05 24.4 0.0 2.5 2 1 0 2 2 2 2 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.1 ETO28840.1 - 0.025 14.2 0.1 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily APOBEC_N PF08210.6 ETO28841.1 - 0.0041 16.7 1.0 0.0076 15.8 0.7 1.5 1 0 0 1 1 1 1 APOBEC-like N-terminal domain Tom37_C PF11801.3 ETO28841.1 - 0.42 10.4 8.5 0.035 13.9 2.4 1.7 2 0 0 2 2 2 0 Tom37 C-terminal domain W2 PF02020.13 ETO28841.1 - 4.9 7.1 9.9 13 5.7 5.5 2.5 2 1 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon HTH_9 PF08221.6 ETO28843.1 - 0.065 13.1 0.1 4.4 7.2 0.0 2.6 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain IBN_N PF03810.14 ETO28844.1 - 0.019 14.8 2.5 0.025 14.4 0.6 2.0 2 0 0 2 2 2 0 Importin-beta N-terminal domain PKD PF00801.15 ETO28846.1 - 0.028 14.1 0.3 0.066 12.9 0.2 1.6 1 0 0 1 1 1 0 PKD domain TBX PF12598.3 ETO28848.1 - 0.059 13.7 1.0 0.13 12.6 0.7 1.6 1 0 0 1 1 1 0 T-box transcription factor DUF2217 PF10265.4 ETO28850.1 - 0.14 10.8 0.5 0.18 10.5 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) WD40 PF00400.27 ETO28851.1 - 1.2e-54 180.2 21.1 3.1e-11 42.7 0.1 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO28851.1 - 3.4e-07 28.7 2.0 0.066 11.3 0.1 3.9 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Ricin_B_lectin PF00652.17 ETO28851.1 - 6.3e-05 23.0 0.3 0.011 15.7 0.0 3.0 3 1 0 3 3 3 1 Ricin-type beta-trefoil lectin domain eIF2A PF08662.6 ETO28851.1 - 0.00012 21.8 0.0 0.11 12.1 0.0 2.7 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 ETO28851.1 - 0.00018 20.3 7.8 1 8.0 0.2 4.8 1 1 3 4 4 4 3 Nup133 N terminal like Coatomer_WDAD PF04053.9 ETO28851.1 - 0.0053 15.6 0.0 0.099 11.4 0.0 2.3 1 1 0 2 2 2 1 Coatomer WD associated region NTNH_C PF08470.5 ETO28851.1 - 0.0073 15.9 0.0 0.015 14.9 0.0 1.5 2 0 0 2 2 2 1 Nontoxic nonhaemagglutinin C-terminal PD40 PF07676.7 ETO28851.1 - 0.021 14.4 6.3 14 5.4 0.0 5.0 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO28851.1 - 0.12 10.6 1.0 6.6 4.9 0.0 2.9 2 1 1 3 3 3 0 Cytochrome D1 heme domain CLPTM1 PF05602.7 ETO28854.1 - 0.1 11.3 4.6 0.11 11.2 3.2 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) BHD_2 PF10404.4 ETO28854.1 - 0.33 11.2 6.7 0.77 10.1 4.7 1.7 1 1 0 1 1 1 0 Rad4 beta-hairpin domain 2 HNOBA PF07701.9 ETO28854.1 - 3.9 6.6 12.9 14 4.8 9.0 1.7 1 1 0 1 1 1 0 Heme NO binding associated NPR3 PF03666.8 ETO28854.1 - 4.5 5.6 11.2 4.5 5.6 7.7 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pox_Ag35 PF03286.9 ETO28854.1 - 6.9 6.1 14.7 7.5 6.0 10.2 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Bunya_G1 PF03557.10 ETO28855.1 - 0.012 13.4 1.7 0.013 13.3 1.2 1.0 1 0 0 1 1 1 0 Bunyavirus glycoprotein G1 DUF3764 PF12594.3 ETO28855.1 - 0.096 12.4 0.1 0.23 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3764) TBX PF12598.3 ETO28856.1 - 0.58 10.5 3.5 0.66 10.3 0.3 2.3 1 1 2 3 3 3 0 T-box transcription factor Lipase_GDSL_2 PF13472.1 ETO28862.1 - 2.4e-16 60.3 0.0 3.6e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 ETO28862.1 - 5.9e-05 22.9 0.0 0.00013 21.9 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase BLVR PF06375.6 ETO28863.1 - 8 6.2 17.4 2.1 8.1 8.8 1.9 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Sarcoglycan_2 PF05510.8 ETO28864.1 - 0.011 14.1 0.0 0.014 13.7 0.0 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon SKG6 PF08693.5 ETO28864.1 - 0.029 13.6 1.4 0.063 12.6 0.9 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMEM173 PF15009.1 ETO28864.1 - 0.034 12.9 0.1 0.068 11.9 0.0 1.5 2 0 0 2 2 2 0 Transmembrane protein 173 DUF4448 PF14610.1 ETO28864.1 - 0.067 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) RCR PF12273.3 ETO28864.1 - 0.093 13.2 1.0 0.2 12.2 0.7 1.5 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red GKAP PF03359.8 ETO28865.1 - 0.17 11.4 9.5 0.19 11.3 6.6 1.1 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein WD40 PF00400.27 ETO28866.1 - 1.3e-06 28.0 0.2 2.8 7.9 0.0 5.8 6 0 0 6 6 6 2 WD domain, G-beta repeat Vps16_N PF04841.8 ETO28866.1 - 0.0013 17.3 0.1 0.021 13.3 0.1 2.1 2 0 0 2 2 2 1 Vps16, N-terminal region DUF2415 PF10313.4 ETO28866.1 - 0.01 15.4 0.0 0.062 12.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) GAF PF01590.21 ETO28868.1 - 1.3e-09 38.3 0.0 2.6e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 ETO28868.1 - 0.00023 21.2 0.0 0.00049 20.2 0.0 1.6 1 0 0 1 1 1 1 GAF domain FHA PF00498.21 ETO28868.1 - 0.0021 18.1 0.2 0.0074 16.3 0.0 2.1 2 0 0 2 2 2 1 FHA domain Phage_hub_GP28 PF11110.3 ETO28868.1 - 0.016 14.9 0.1 0.037 13.7 0.1 1.6 1 0 0 1 1 1 0 Baseplate hub distal subunit Phage_holin_T PF11031.3 ETO28868.1 - 0.11 11.6 5.9 0.27 10.3 4.1 1.6 1 0 0 1 1 1 0 Bacteriophage T holin DUF4044 PF13253.1 ETO28868.1 - 0.52 9.4 4.5 1.2 8.3 3.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Phage_B PF02304.10 ETO28869.1 - 0.051 13.8 1.1 0.12 12.7 0.8 1.6 1 0 0 1 1 1 0 Scaffold protein B Nucleoplasmin PF03066.10 ETO28870.1 - 0.00089 18.7 0.1 0.00089 18.7 0.1 2.1 2 0 0 2 2 2 1 Nucleoplasmin DUF2615 PF11027.3 ETO28870.1 - 0.0062 16.4 1.0 0.0062 16.4 0.7 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF2615) Mem_trans PF03547.13 ETO28870.1 - 0.02 13.2 0.7 0.029 12.6 0.5 1.2 1 0 0 1 1 1 0 Membrane transport protein PBP1_TM PF14812.1 ETO28870.1 - 0.034 14.4 1.9 0.034 14.4 1.3 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal alpha-hel2 PF14456.1 ETO28870.1 - 0.14 10.9 3.1 0.56 8.9 1.3 2.4 3 0 0 3 3 3 0 Alpha-helical domain 2 DUF2116 PF09889.4 ETO28870.1 - 0.33 10.7 0.1 0.33 10.7 0.1 2.9 3 1 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF1980 PF09323.5 ETO28870.1 - 2 8.1 7.7 0.14 11.8 1.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) WD40 PF00400.27 ETO28871.1 - 7.9e-81 263.3 15.8 8.3e-12 44.5 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO28871.1 - 2.6e-13 50.1 0.2 5.5e-06 26.2 0.0 3.5 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO28871.1 - 1.8e-11 42.9 2.3 0.0042 15.2 0.0 5.1 1 1 4 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO28871.1 - 1.5e-07 30.5 7.7 0.004 15.9 0.1 4.9 1 1 3 4 4 4 2 Nup133 N terminal like PD40 PF07676.7 ETO28871.1 - 5e-07 29.2 1.3 0.12 12.0 0.0 4.9 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO28871.1 - 3.9e-06 26.5 0.2 0.00049 19.6 0.1 2.9 2 1 0 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO28871.1 - 4.2e-06 25.3 0.6 0.005 15.1 0.0 2.9 1 1 3 4 4 4 3 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 ETO28871.1 - 9.4e-06 24.6 1.5 0.046 12.5 0.0 2.7 1 1 1 2 2 2 2 Coatomer WD associated region DUF1652 PF07865.6 ETO28871.1 - 0.0028 17.2 0.1 2.8 7.6 0.0 4.2 5 1 0 5 5 5 1 Protein of unknown function (DUF1652) DUF1258 PF06869.7 ETO28871.1 - 0.0091 15.1 3.8 0.72 8.8 0.3 3.3 2 1 0 3 3 3 1 Protein of unknown function (DUF1258) B_lectin PF01453.19 ETO28871.1 - 0.016 15.0 0.6 0.1 12.4 0.1 2.5 1 1 2 3 3 3 0 D-mannose binding lectin Proteasome_A_N PF10584.4 ETO28871.1 - 0.028 13.7 7.1 16 4.9 0.0 5.0 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Colicin_Ia PF11504.3 ETO28871.1 - 0.13 12.1 0.2 40 4.2 0.0 3.8 4 0 0 4 4 4 0 Colicin Ia Resistin PF06954.6 ETO28871.1 - 0.24 11.7 5.5 9.4 6.5 0.0 4.2 2 1 3 6 6 6 0 Resistin PH_8 PF15409.1 ETO28871.1 - 3.4 7.7 9.1 25 5.0 2.1 4.1 4 2 1 5 5 5 0 Pleckstrin homology domain DUF1336 PF07059.7 ETO28875.1 - 3.7e-45 154.1 0.0 5.4e-45 153.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) HSP70 PF00012.15 ETO28876.1 - 6.1e-92 308.4 11.2 1.2e-50 172.0 0.0 4.7 4 1 0 4 4 4 4 Hsp70 protein MreB_Mbl PF06723.8 ETO28876.1 - 2.2e-07 29.7 0.4 2.2e-06 26.5 0.0 2.4 3 0 0 3 3 3 1 MreB/Mbl protein DUF903 PF06004.7 ETO28876.1 - 0.02 14.4 0.2 0.065 12.7 0.2 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF903) DUF3440 PF11922.3 ETO28876.1 - 4.3 6.8 10.2 0.12 11.9 0.8 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3440) Cullin PF00888.17 ETO28877.1 - 2e-113 379.9 24.7 3.9e-113 379.0 17.1 1.4 1 0 0 1 1 1 1 Cullin family Enkurin PF13864.1 ETO28877.1 - 0.072 13.3 0.4 0.072 13.3 0.2 2.4 2 0 0 2 2 2 0 Calmodulin-binding PRD PF00874.15 ETO28877.1 - 0.13 12.3 4.9 0.39 10.8 0.2 3.5 3 1 0 3 3 3 0 PRD domain WD40 PF00400.27 ETO28879.1 - 5.5e-31 105.3 10.0 2.9e-10 39.6 0.6 4.4 4 1 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO28879.1 - 0.00019 19.6 0.1 0.089 10.9 0.0 3.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO28879.1 - 0.0035 16.1 5.5 0.0047 15.7 2.8 1.8 1 1 1 2 2 2 1 Nup133 N terminal like SprB PF13573.1 ETO28879.1 - 0.22 11.1 3.6 7.2 6.2 0.0 3.1 3 0 0 3 3 3 0 SprB repeat Ion_trans PF00520.26 ETO28880.1 - 1.7e-21 76.3 57.9 7.7e-19 67.7 19.1 3.0 3 0 0 3 3 3 2 Ion transport protein EF-hand_6 PF13405.1 ETO28880.1 - 0.00013 21.5 1.1 0.081 12.8 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 ETO28880.1 - 0.0011 19.0 0.6 0.35 11.0 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 ETO28880.1 - 0.002 17.3 3.2 0.078 12.3 0.7 2.7 2 0 0 2 2 2 2 EF hand DUF2946 PF11162.3 ETO28881.1 - 0.1 12.7 0.2 4.1 7.6 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) CHAT PF12770.2 ETO28883.1 - 2.3e-06 26.9 0.0 7.5e-06 25.2 0.0 1.6 1 1 0 1 1 1 1 CHAT domain AAA_19 PF13245.1 ETO28883.1 - 0.16 11.7 0.6 2.4 7.9 0.0 2.7 3 0 0 3 3 3 0 Part of AAA domain F420_oxidored PF03807.12 ETO28884.1 - 3e-15 56.4 0.0 4.2e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.12 ETO28884.1 - 3.5e-08 32.6 0.4 4.4e-08 32.3 0.3 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_Gly3P_dh_N PF01210.18 ETO28884.1 - 6.3e-08 32.4 6.5 2e-06 27.6 4.5 2.1 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 ETO28884.1 - 9.9e-05 22.2 0.0 0.00016 21.5 0.0 1.3 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 ETO28884.1 - 0.0011 18.4 3.5 0.008 15.6 2.4 1.9 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_C PF03720.10 ETO28884.1 - 0.0062 16.6 0.0 0.0092 16.1 0.0 1.3 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain IlvN PF07991.7 ETO28884.1 - 0.034 13.5 0.0 0.043 13.1 0.0 1.1 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain UDPG_MGDP_dh_N PF03721.9 ETO28884.1 - 0.12 11.6 0.3 0.73 9.1 0.2 2.0 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Herpes_gI PF01688.12 ETO28885.1 - 0.0042 16.2 0.3 0.0061 15.6 0.2 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein I Malic_M PF03949.10 ETO28885.1 - 0.1 12.1 0.0 0.37 10.3 0.0 1.7 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Tudor-knot PF11717.3 ETO28886.1 - 9.8e-07 28.3 9.0 6.6e-06 25.7 6.2 2.0 1 1 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF2207 PF09972.4 ETO28887.1 - 0.034 12.7 0.4 0.039 12.5 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) eRF1_3 PF03465.10 ETO28888.1 - 0.0068 16.6 1.2 0.3 11.3 0.5 2.4 2 0 0 2 2 2 1 eRF1 domain 3 DUF1203 PF06718.6 ETO28888.1 - 0.022 14.5 0.2 0.053 13.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1203) NPV_P10 PF05531.7 ETO28888.1 - 0.44 10.8 3.5 13 6.1 0.3 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein TPR_8 PF13181.1 ETO28889.1 - 0.0053 16.4 0.1 0.014 15.1 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO28889.1 - 0.021 14.7 0.9 0.04 13.8 0.5 1.6 1 1 0 1 1 1 0 Tetratricopeptide repeat Apc3 PF12895.2 ETO28889.1 - 0.025 14.7 1.2 0.025 14.7 0.8 1.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 ETO28889.1 - 0.15 12.0 1.7 0.22 11.5 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat LAGLIDADG_1 PF00961.14 ETO28890.1 - 0.026 15.0 4.4 0.033 14.7 2.1 1.8 1 1 1 2 2 2 0 LAGLIDADG endonuclease PIG-P PF08510.7 ETO28891.1 - 0.75 9.4 5.9 1.7 8.2 4.1 1.8 1 1 0 1 1 1 0 PIG-P Fip1 PF05182.8 ETO28892.1 - 7.9e-20 69.8 2.8 1.4e-19 69.0 1.9 1.4 1 0 0 1 1 1 1 Fip1 motif PAT1 PF09770.4 ETO28893.1 - 0.059 11.6 19.5 0.086 11.0 13.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2324 PF10086.4 ETO28893.1 - 0.19 10.8 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 Putative membrane peptidase family (DUF2324) CD34_antigen PF06365.7 ETO28894.1 - 0.0074 15.9 0.1 0.012 15.3 0.1 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family Shisa PF13908.1 ETO28894.1 - 0.051 13.7 0.1 0.066 13.3 0.1 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF3481 PF11980.3 ETO28894.1 - 0.14 11.9 0.3 0.25 11.1 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3481) IFT43 PF15305.1 ETO28895.1 - 3.7e-06 27.0 0.3 4.4e-06 26.7 0.2 1.3 1 1 0 1 1 1 1 Intraflagellar transport protein 43 FlgN PF05130.7 ETO28895.1 - 0.064 13.4 0.0 0.076 13.2 0.0 1.1 1 0 0 1 1 1 0 FlgN protein P63C PF10546.4 ETO28896.1 - 0.082 12.8 0.2 0.082 12.8 0.1 2.3 1 1 1 3 3 3 0 P63C domain SYF2 PF08231.7 ETO28896.1 - 0.6 10.2 11.7 0.93 9.6 8.1 1.5 1 1 0 1 1 1 0 SYF2 splicing factor ArdA PF07275.6 ETO28897.1 - 2.2 8.5 9.5 3.5 7.8 0.0 3.6 1 1 3 4 4 4 0 Antirestriction protein (ArdA) Baculo_PEP_C PF04513.7 ETO28897.1 - 3 7.6 12.3 0.089 12.6 1.2 3.4 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lig_chan PF00060.21 ETO28898.1 - 0.083 12.6 0.1 0.45 10.2 0.0 2.0 2 0 0 2 2 2 0 Ligand-gated ion channel SUI1 PF01253.17 ETO28900.1 - 8.2e-10 38.3 1.4 1.1e-09 37.9 0.1 1.9 2 1 0 2 2 2 1 Translation initiation factor SUI1 SURF2 PF05477.6 ETO28900.1 - 0.017 14.2 0.8 0.017 14.2 0.6 1.5 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) SWIB PF02201.13 ETO28900.1 - 0.064 12.9 0.3 0.18 11.5 0.1 1.8 1 1 0 1 1 1 0 SWIB/MDM2 domain AntA PF08346.7 ETO28900.1 - 0.074 13.2 0.5 0.27 11.4 0.1 2.0 2 0 0 2 2 2 0 AntA/AntB antirepressor WD40 PF00400.27 ETO28901.1 - 2.8e-75 245.7 19.7 1.4e-10 40.5 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO28901.1 - 2e-09 36.1 4.4 0.38 8.8 0.0 6.5 1 1 4 5 5 5 5 Nucleoporin Nup120/160 DUF1258 PF06869.7 ETO28901.1 - 6.9e-06 25.3 0.2 0.014 14.5 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF1258) Nucleoporin_N PF08801.6 ETO28901.1 - 8.4e-06 24.7 8.9 0.32 9.7 0.1 5.3 2 2 4 6 6 6 4 Nup133 N terminal like PQQ_2 PF13360.1 ETO28901.1 - 2.3e-05 23.9 0.0 6e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO28901.1 - 3.4e-05 22.3 0.1 0.0093 14.2 0.0 3.0 2 1 1 3 3 3 3 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO28901.1 - 0.00011 21.3 1.1 3.5 6.6 0.0 4.4 2 1 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Resistin PF06954.6 ETO28901.1 - 0.085 13.1 0.3 19 5.5 0.0 4.2 5 1 0 5 5 5 0 Resistin PT-HINT PF07591.6 ETO28902.1 - 0.022 14.6 0.1 0.024 14.5 0.1 1.1 1 0 0 1 1 1 0 Pretoxin HINT domain LEM PF03020.10 ETO28903.1 - 0.084 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 LEM domain PTPS PF01242.14 ETO28903.1 - 0.092 12.4 0.1 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 6-pyruvoyl tetrahydropterin synthase DUF1454 PF07305.7 ETO28903.1 - 0.099 11.7 2.4 0.16 11.0 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) DUF2660 PF10859.3 ETO28903.1 - 0.12 12.5 0.7 0.25 11.6 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) DUF3439 PF11921.3 ETO28903.1 - 0.21 11.3 7.7 0.35 10.6 5.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 ETO28903.1 - 0.34 8.8 11.1 0.46 8.4 7.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.12 ETO28903.1 - 0.58 9.9 15.6 1.1 9.0 10.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein A_deaminase PF00962.17 ETO28906.1 - 3.3e-46 157.7 0.5 1.3e-45 155.7 0.3 1.8 1 1 0 1 1 1 1 Adenosine/AMP deaminase Ras PF00071.17 ETO28908.1 - 6.6e-25 87.3 3.2 2.9e-18 65.7 0.2 2.1 2 0 0 2 2 2 2 Ras family AAA_22 PF13401.1 ETO28908.1 - 0.00065 19.8 0.1 0.0011 19.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 ETO28908.1 - 0.0021 18.5 0.5 0.06 13.8 0.1 2.4 1 1 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 ETO28908.1 - 0.0032 17.4 0.1 0.0058 16.6 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 ETO28908.1 - 0.004 16.3 0.0 0.013 14.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_5 PF07728.9 ETO28908.1 - 0.018 14.7 0.1 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Pox_A32 PF04665.7 ETO28908.1 - 0.052 12.8 0.1 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein ABC_tran PF00005.22 ETO28908.1 - 0.072 13.3 0.2 0.16 12.2 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA PF00004.24 ETO28908.1 - 0.086 13.0 0.1 0.54 10.4 0.0 1.9 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 ETO28908.1 - 0.09 12.3 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 ETO28908.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain BLVR PF06375.6 ETO28909.1 - 0.016 15.0 4.4 0.019 14.7 3.1 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Thg1C PF14413.1 ETO28909.1 - 0.35 10.5 6.2 0.46 10.1 4.3 1.3 1 1 0 1 1 1 0 Thg1 C terminal domain O-ag_pol_Wzy PF14296.1 ETO28909.1 - 0.43 9.0 1.8 0.52 8.8 1.2 1.1 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy DUF2393 PF09624.5 ETO28909.1 - 0.77 9.2 9.5 0.81 9.2 3.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2393) Ribosomal_L18ae PF01775.12 ETO28910.1 - 0.45 10.4 8.9 0.26 11.2 1.2 2.5 2 0 0 2 2 2 0 Ribosomal L18ae/LX protein domain Trypan_PARP PF05887.6 ETO28911.1 - 3.4 7.4 12.5 5.5 6.7 8.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Zip PF02535.17 ETO28911.1 - 5.2 5.9 6.8 8.1 5.3 4.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Macoilin PF09726.4 ETO28911.1 - 6.6 4.8 32.3 8.2 4.5 22.4 1.1 1 0 0 1 1 1 0 Transmembrane protein HECT PF00632.20 ETO28912.1 - 3.2e-56 190.7 1.0 3.2e-56 190.7 0.7 1.9 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) VWA PF00092.23 ETO28914.1 - 1.6e-07 31.2 0.0 3.7e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 ETO28914.1 - 9.2e-06 25.4 0.3 3.1e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.1 ETO28914.1 - 7.7e-05 22.8 0.0 0.00019 21.6 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Sec62 PF03839.11 ETO28914.1 - 0.73 9.1 4.2 1.3 8.4 2.9 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 POX PF07526.6 ETO28914.1 - 7.2 6.8 8.2 0.85 9.8 2.2 1.8 2 0 0 2 2 2 0 Associated with HOX Imm29 PF15575.1 ETO28915.1 - 0.071 12.7 0.1 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 29 IPK PF03770.11 ETO28916.1 - 3e-08 33.5 0.2 3e-07 30.2 0.1 2.0 1 1 0 1 1 1 1 Inositol polyphosphate kinase IPK PF03770.11 ETO28917.1 - 0.011 15.3 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 0 Inositol polyphosphate kinase DUF1253 PF06862.7 ETO28918.1 - 1.2e-84 284.3 19.4 1.2e-84 284.3 13.5 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1253) Nucleoplasmin PF03066.10 ETO28918.1 - 0.0027 17.2 0.9 0.0027 17.2 0.6 3.8 3 0 0 3 3 3 1 Nucleoplasmin DUF1768 PF08719.6 ETO28919.1 - 3.2e-43 147.1 0.7 5.5e-43 146.4 0.5 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1768) FdhE PF04216.7 ETO28920.1 - 0.099 12.3 0.3 0.15 11.7 0.2 1.3 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation CENP-F_leu_zip PF10473.4 ETO28920.1 - 0.1 12.4 10.8 0.1 12.4 6.8 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-RING_2 PF13639.1 ETO28921.1 - 0.0047 16.7 2.7 0.0085 15.8 1.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 ETO28921.1 - 0.027 14.1 5.5 0.056 13.1 3.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 ETO28921.1 - 0.053 13.5 4.8 0.097 12.7 3.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO28921.1 - 0.08 12.6 3.8 0.22 11.1 2.6 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Orthopox_F6 PF06601.7 ETO28921.1 - 0.092 12.6 0.7 0.092 12.6 0.5 1.9 2 0 0 2 2 2 0 Orthopoxvirus F6 protein zf-C3HC4_3 PF13920.1 ETO28921.1 - 0.22 11.2 2.7 0.36 10.5 1.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1764 PF08576.5 ETO28921.1 - 0.61 10.8 14.4 2.2 9.1 5.4 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) zf-RING_UBOX PF13445.1 ETO28921.1 - 1.1 9.0 4.4 3.9 7.2 3.0 2.0 1 0 0 1 1 1 0 RING-type zinc-finger Ribonuc_red_2_N PF08471.5 ETO28924.1 - 0.012 15.6 0.1 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 Class II vitamin B12-dependent ribonucleotide reductase DUF1068 PF06364.7 ETO28924.1 - 0.27 10.8 0.1 0.27 10.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1068) Daxx PF03344.10 ETO28924.1 - 0.44 8.9 11.0 0.55 8.6 7.6 1.1 1 0 0 1 1 1 0 Daxx Family WD40 PF00400.27 ETO28925.1 - 1e-07 31.5 2.3 0.0026 17.5 0.1 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat Peptidase_C28 PF05408.6 ETO28925.1 - 0.0017 17.8 0.0 0.0027 17.1 0.0 1.4 1 0 0 1 1 1 1 Foot-and-mouth virus L-proteinase LRR_4 PF12799.2 ETO28926.1 - 2.2e-26 90.9 39.3 1.6e-08 33.9 2.3 7.2 4 2 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO28926.1 - 1.8e-13 50.0 39.3 0.00055 19.6 1.7 5.3 5 1 1 6 6 6 5 Leucine rich repeat LRR_1 PF00560.28 ETO28926.1 - 1.8e-10 39.3 35.5 0.082 12.9 0.1 11.5 10 2 1 11 11 11 6 Leucine Rich Repeat LRR_7 PF13504.1 ETO28926.1 - 1.6e-06 27.3 36.7 1.1 9.7 0.0 10.9 10 2 1 11 11 11 3 Leucine rich repeat LRR_9 PF14580.1 ETO28926.1 - 5e-05 22.9 10.9 0.0016 18.0 0.2 3.5 4 0 0 4 4 4 2 Leucine-rich repeat LRR_6 PF13516.1 ETO28926.1 - 0.0063 16.4 58.2 0.36 11.0 0.3 12.0 13 2 2 15 15 15 5 Leucine Rich repeat TPR_12 PF13424.1 ETO28927.1 - 1e-78 259.2 18.3 6.8e-23 80.4 0.4 4.6 2 2 4 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETO28927.1 - 1.8e-37 125.3 34.8 1e-08 34.3 0.1 7.3 7 1 0 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.1 ETO28927.1 - 6.6e-37 122.3 5.3 1.7e-07 30.5 0.0 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETO28927.1 - 1.1e-36 124.2 21.1 7.2e-15 54.3 0.1 4.2 3 1 1 4 4 4 4 TPR repeat TPR_2 PF07719.12 ETO28927.1 - 1.2e-32 109.1 20.4 2.8e-06 26.8 0.4 6.8 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_10 PF13374.1 ETO28927.1 - 9e-32 108.0 0.0 1.3e-05 24.9 0.0 6.3 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETO28927.1 - 1e-27 93.7 40.6 6.7e-07 28.6 0.3 6.9 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 ETO28927.1 - 1.5e-23 80.9 5.3 0.0091 16.1 0.0 6.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 ETO28927.1 - 1.7e-12 47.6 0.0 0.045 14.4 0.0 5.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO28927.1 - 1.8e-12 46.8 3.1 0.0014 18.9 0.1 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO28927.1 - 7.4e-12 44.7 0.0 0.52 11.0 0.0 5.7 7 0 0 7 7 5 3 Tetratricopeptide repeat PPR PF01535.15 ETO28927.1 - 2e-07 30.4 16.3 0.041 13.8 0.0 6.5 7 0 0 7 7 7 2 PPR repeat MIT PF04212.13 ETO28927.1 - 2.8e-07 30.3 12.4 0.043 13.6 0.0 5.8 5 0 0 5 5 5 2 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 ETO28927.1 - 4.1e-07 30.0 19.9 0.024 14.7 1.6 5.8 1 1 5 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 Pep3_Vps18 PF05131.9 ETO28927.1 - 9.5e-05 21.8 3.9 3.6 7.0 0.0 5.3 5 0 0 5 5 5 1 Pep3/Vps18/deep orange family TPR_3 PF07720.7 ETO28927.1 - 0.00026 20.6 24.0 1.2 9.0 0.4 6.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO28927.1 - 0.00033 20.9 3.7 3.7 7.9 0.1 4.5 2 1 4 6 6 6 1 Tetratricopeptide repeat DUF3568 PF12092.3 ETO28927.1 - 0.0029 17.3 0.5 0.9 9.2 0.0 3.9 1 1 3 4 4 4 2 Protein of unknown function (DUF3568) OpcA PF07239.6 ETO28927.1 - 0.0084 15.0 0.1 0.075 11.9 0.0 2.1 2 0 0 2 2 2 1 Outer membrane protein OpcA DUF3856 PF12968.2 ETO28927.1 - 0.013 15.2 0.4 6 6.6 0.0 3.6 1 1 2 3 3 3 0 Domain of Unknown Function (DUF3856) bPH_3 PF14470.1 ETO28927.1 - 0.071 13.3 1.1 1 9.6 0.0 3.1 1 1 2 3 3 3 0 Bacterial PH domain Corona_NS2 PF04753.7 ETO28927.1 - 0.074 13.0 0.4 1.9 8.4 0.1 2.4 2 0 0 2 2 2 0 Coronavirus non-structural protein NS2 RPN7 PF10602.4 ETO28927.1 - 0.084 12.2 8.1 0.66 9.3 0.2 3.8 3 1 1 4 4 4 0 26S proteasome subunit RPN7 KH_4 PF13083.1 ETO28927.1 - 0.086 12.4 0.0 0.88 9.2 0.0 2.3 1 1 1 2 2 2 0 KH domain PPR_2 PF13041.1 ETO28927.1 - 0.33 10.9 9.3 4.2 7.4 0.0 5.1 7 0 0 7 7 6 0 PPR repeat family CLTH PF10607.4 ETO28927.1 - 1.5 8.4 7.8 9.3 5.9 0.0 3.4 3 1 0 3 3 3 0 CTLH/CRA C-terminal to LisH motif domain RsbRD_N PF14361.1 ETO28928.1 - 0.00016 22.0 1.4 0.0012 19.2 0.1 2.4 2 1 0 2 2 2 1 RsbT co-antagonist protein rsbRD N-terminal domain DUF3106 PF11304.3 ETO28928.1 - 0.0023 18.3 4.6 0.13 12.6 0.5 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3106) DUF4618 PF15397.1 ETO28928.1 - 0.0066 15.8 7.3 0.015 14.6 1.2 2.2 1 1 0 2 2 2 1 Domain of unknown function (DUF4618) LXG PF04740.7 ETO28928.1 - 0.031 14.0 2.8 0.11 12.3 0.9 2.1 1 1 0 2 2 2 0 LXG domain of WXG superfamily MbeD_MobD PF04899.7 ETO28928.1 - 0.036 13.9 3.5 5.9 6.8 0.3 3.4 3 1 0 3 3 3 0 MbeD/MobD like tRNA-synt_1d PF00750.14 ETO28928.1 - 0.12 11.1 2.1 0.14 10.9 1.5 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (R) Myb_DNA-bind_6 PF13921.1 ETO28928.1 - 0.17 12.0 2.0 0.47 10.6 1.1 2.1 1 1 1 2 2 2 0 Myb-like DNA-binding domain Tropomyosin PF00261.15 ETO28928.1 - 0.26 10.3 13.4 0.2 10.7 7.7 2.0 1 1 1 2 2 2 0 Tropomyosin DUF615 PF04751.9 ETO28928.1 - 0.35 10.5 5.8 1.7 8.2 3.9 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF615) zf-ZPR1 PF03367.8 ETO28928.1 - 0.42 9.7 2.1 0.91 8.6 0.3 2.0 1 1 1 2 2 2 0 ZPR1 zinc-finger domain DASH_Duo1 PF08651.5 ETO28928.1 - 0.51 9.9 3.2 3 7.5 0.3 2.4 1 1 1 2 2 2 0 DASH complex subunit Duo1 HALZ PF02183.13 ETO28928.1 - 0.79 9.4 6.4 0.44 10.2 0.2 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper IncA PF04156.9 ETO28928.1 - 0.99 8.9 13.3 0.77 9.3 5.2 2.1 1 1 1 2 2 2 0 IncA protein DUF904 PF06005.7 ETO28928.1 - 1.1 9.5 10.7 8.6 6.7 7.4 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Fzo_mitofusin PF04799.8 ETO28928.1 - 1.2 8.4 5.2 1.2 8.5 2.5 1.8 2 1 0 2 2 2 0 fzo-like conserved region DUF972 PF06156.8 ETO28928.1 - 1.8 8.9 10.2 1.4 9.2 4.4 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF972) APG6 PF04111.7 ETO28928.1 - 2.4 7.1 11.7 0.16 10.9 2.9 1.9 1 1 1 2 2 2 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 ETO28928.1 - 2.4 8.1 10.9 0.94 9.5 3.6 2.6 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Snf7 PF03357.16 ETO28928.1 - 3.4 7.0 11.1 0.92 8.8 0.1 3.1 1 1 1 2 2 2 0 Snf7 DUF4047 PF13256.1 ETO28928.1 - 3.6 7.5 7.0 3.8 7.4 1.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) bZIP_Maf PF03131.12 ETO28928.1 - 5.6 7.3 9.2 10 6.4 0.1 3.5 3 1 0 3 3 3 0 bZIP Maf transcription factor OmpH PF03938.9 ETO28928.1 - 6.7 6.6 12.7 1.6e+02 2.1 8.8 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) KH_1 PF00013.24 ETO28929.1 - 2.4e-24 84.7 10.4 3.2e-11 42.6 0.0 4.4 4 0 0 4 4 4 4 KH domain KH_3 PF13014.1 ETO28929.1 - 4e-17 61.4 4.2 1.8e-05 24.2 0.0 3.7 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 ETO28929.1 - 6.8e-05 22.3 0.3 3.9 7.0 0.0 3.6 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 ETO28929.1 - 0.024 14.2 0.1 3.9 7.1 0.0 2.5 2 0 0 2 2 2 0 KH domain Abi PF02517.11 ETO28931.1 - 2.3e-12 46.8 4.3 2.3e-12 46.8 3.0 2.0 2 1 0 2 2 2 1 CAAX protease self-immunity Lysis_S PF04971.7 ETO28931.1 - 0.1 12.3 0.1 3.7 7.3 0.0 2.6 2 0 0 2 2 2 0 Lysis protein S p450 PF00067.17 ETO28932.1 - 3.7e-23 81.7 0.0 4.9e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3038 PF11237.3 ETO28932.1 - 0.0081 15.9 0.5 0.099 12.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3038) p450 PF00067.17 ETO28933.1 - 3.3e-59 200.6 0.0 3.8e-59 200.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Kelch_6 PF13964.1 ETO28934.1 - 9.2e-09 35.1 6.0 8.2e-05 22.6 0.1 4.6 4 1 1 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO28934.1 - 6.7e-07 28.9 3.7 0.029 14.1 0.1 4.4 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO28934.1 - 6.9e-06 25.5 5.9 0.18 11.3 0.0 4.7 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO28934.1 - 0.01 15.7 2.2 1 9.4 0.2 3.4 3 0 0 3 3 3 0 Kelch motif Kelch_3 PF13415.1 ETO28934.1 - 0.01 15.9 0.1 0.01 15.9 0.1 4.1 5 0 0 5 5 5 0 Galactose oxidase, central domain BCHF PF07284.6 ETO28934.1 - 0.012 15.4 0.4 3.9 7.3 0.0 2.9 3 1 0 3 3 3 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) Kelch_2 PF07646.10 ETO28934.1 - 0.016 14.9 2.8 6.9 6.6 0.2 3.6 3 0 0 3 3 3 0 Kelch motif DUF99 PF01949.11 ETO28934.1 - 0.11 11.5 0.0 0.38 9.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF99 Spc24 PF08286.6 ETO28934.1 - 0.36 10.5 0.0 0.36 10.5 0.0 2.6 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 Secretin_N_2 PF07655.8 ETO28934.1 - 7.5 7.0 11.5 19 5.7 8.0 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain TLP-20 PF06088.6 ETO28935.1 - 0.0088 15.7 2.0 0.013 15.1 1.4 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PH PF00169.24 ETO28936.1 - 1.8e-07 31.3 0.2 1.8e-07 31.3 0.1 3.0 2 2 0 2 2 2 1 PH domain PH_11 PF15413.1 ETO28936.1 - 1.1e-05 25.6 0.5 1.1e-05 25.6 0.3 2.5 3 1 0 3 3 3 1 Pleckstrin homology domain PH_9 PF15410.1 ETO28936.1 - 0.073 13.2 1.5 0.22 11.7 0.1 2.5 2 1 0 2 2 2 0 Pleckstrin homology domain Serglycin PF04360.7 ETO28937.1 - 0.00016 21.3 0.0 0.00045 19.9 0.0 1.8 1 0 0 1 1 1 1 Serglycin Seryl_tRNA_N PF02403.17 ETO28937.1 - 0.0027 17.6 4.3 0.0027 17.6 3.0 7.5 3 2 3 6 6 6 1 Seryl-tRNA synthetase N-terminal domain DUF3584 PF12128.3 ETO28937.1 - 1.2 6.4 78.3 0.014 12.7 38.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) DUF3439 PF11921.3 ETO28938.1 - 0.77 9.5 7.7 0.06 13.1 1.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) EAF PF09816.4 ETO28940.1 - 0.36 10.8 5.3 0.9 9.5 3.6 1.9 1 1 0 1 1 1 0 RNA polymerase II transcription elongation factor ALMT PF11744.3 ETO28940.1 - 1.8 7.1 5.1 2.2 6.8 3.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter UPF0564 PF10595.4 ETO28941.1 - 0.00076 18.4 33.6 0.0025 16.7 0.1 3.2 2 1 1 3 3 3 2 Uncharacterised protein family UPF0564 ApoO PF09769.4 ETO28941.1 - 0.036 13.7 6.5 0.23 11.1 1.1 2.5 2 0 0 2 2 2 0 Apolipoprotein O Fzo_mitofusin PF04799.8 ETO28941.1 - 0.37 10.1 9.5 0.18 11.1 2.7 2.6 2 1 0 2 2 2 0 fzo-like conserved region DUF342 PF03961.8 ETO28941.1 - 8.1 4.7 15.8 4.2 5.6 9.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) ICEA PF05315.6 ETO28942.1 - 0.03 13.6 1.2 0.046 13.0 0.5 1.4 1 1 1 2 2 2 0 ICEA Protein DUF3713 PF12506.3 ETO28942.1 - 0.038 14.0 3.1 0.062 13.3 1.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3713) Stk19 PF10494.4 ETO28942.1 - 0.073 12.4 4.0 0.087 12.2 2.8 1.1 1 0 0 1 1 1 0 Serine-threonine protein kinase 19 Fmp27_WPPW PF10359.4 ETO28942.1 - 0.19 10.0 9.8 0.23 9.8 6.8 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Tox-REase-2 PF15646.1 ETO28942.1 - 0.43 10.4 3.2 0.65 9.8 2.1 1.5 1 1 0 1 1 1 0 Restriction endonuclease fold toxin 2 V_ATPase_I PF01496.14 ETO28942.1 - 0.5 8.1 9.7 0.56 7.9 6.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMPIT PF07851.8 ETO28942.1 - 1.2 8.1 9.4 1.4 7.8 6.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4337 PF14235.1 ETO28942.1 - 1.6 8.5 7.3 1.9 8.2 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) AAA_23 PF13476.1 ETO28942.1 - 1.7 8.8 11.0 2.1 8.6 7.6 1.1 1 0 0 1 1 1 0 AAA domain DUF607 PF04678.8 ETO28942.1 - 2 8.3 7.8 2.6 7.9 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF607 Bap31 PF05529.7 ETO28942.1 - 2.2 7.6 11.8 2 7.8 7.6 1.4 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like YABBY PF04690.8 ETO28942.1 - 2.9 8.0 5.4 2.8 8.1 3.2 1.3 1 1 0 1 1 1 0 YABBY protein IncA PF04156.9 ETO28942.1 - 3.9 7.0 15.8 5.6 6.5 10.9 1.2 1 0 0 1 1 1 0 IncA protein Fzo_mitofusin PF04799.8 ETO28942.1 - 4.2 6.7 11.2 4.9 6.5 7.8 1.1 1 0 0 1 1 1 0 fzo-like conserved region DUF745 PF05335.8 ETO28942.1 - 8.2 5.8 10.8 11 5.5 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Filament PF00038.16 ETO28943.1 - 0.006 16.0 23.0 0.042 13.3 15.9 2.5 1 1 0 1 1 1 1 Intermediate filament protein Syntaxin PF00804.20 ETO28943.1 - 0.023 14.8 6.5 0.023 14.8 4.5 3.0 1 1 0 2 2 2 0 Syntaxin Transposase_1 PF01359.13 ETO28943.1 - 0.065 13.0 3.0 0.41 10.4 0.3 2.6 2 0 0 2 2 2 0 Transposase (partial DDE domain) DUF883 PF05957.8 ETO28943.1 - 0.14 12.5 6.0 2.8 8.3 0.7 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) YlqD PF11068.3 ETO28943.1 - 0.15 12.0 28.7 0.74 9.8 8.2 2.2 1 1 0 2 2 2 0 YlqD protein HXXSHH PF07586.6 ETO28943.1 - 0.15 10.9 10.8 0.092 11.6 2.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1552) SF-assemblin PF06705.6 ETO28943.1 - 0.2 10.7 16.3 0.28 10.3 11.3 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin bZIP_1 PF00170.16 ETO28943.1 - 0.36 10.8 16.1 1.3 9.0 1.1 3.3 3 0 0 3 3 3 0 bZIP transcription factor Init_tRNA_PT PF04179.7 ETO28943.1 - 0.78 8.5 16.4 0.014 14.3 2.1 2.0 1 1 1 2 2 2 0 Initiator tRNA phosphoribosyl transferase YvrJ PF12841.2 ETO28943.1 - 1.4 8.2 3.5 6.7 6.1 0.1 3.0 3 0 0 3 3 3 0 YvrJ protein family OGG_N PF07934.7 ETO28943.1 - 2.6 8.0 9.4 10 6.1 5.7 2.3 1 1 0 1 1 1 0 8-oxoguanine DNA glycosylase, N-terminal domain Tup_N PF08581.5 ETO28943.1 - 3.4 7.9 22.3 2.9 8.1 8.3 3.0 2 1 1 3 3 3 0 Tup N-terminal HSCB_C PF07743.8 ETO28943.1 - 4.6 7.7 14.9 0.34 11.4 1.5 3.2 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain Epimerase PF01370.16 ETO28944.1 - 4.6e-48 163.6 0.0 4.2e-47 160.5 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETO28944.1 - 2e-13 49.6 0.0 4.5e-13 48.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 ETO28944.1 - 2.8e-12 46.1 0.1 9.8e-11 41.0 0.1 2.5 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 ETO28944.1 - 4.6e-11 42.1 0.0 4.7e-09 35.5 0.0 2.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 ETO28944.1 - 5.2e-09 35.4 0.0 4.4e-08 32.3 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 ETO28944.1 - 0.074 12.9 0.0 0.44 10.4 0.0 1.9 2 0 0 2 2 2 0 short chain dehydrogenase IU_nuc_hydro PF01156.14 ETO28945.1 - 7.6e-10 38.4 0.0 1.1e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase tRNA-synt_1e PF01406.14 ETO28945.1 - 0.019 14.1 0.0 0.035 13.2 0.0 1.4 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain TFIIS_M PF07500.9 ETO28947.1 - 0.0017 18.4 7.1 0.0017 18.4 4.9 3.3 3 1 1 4 4 4 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 ETO28947.1 - 0.029 14.8 0.0 0.076 13.4 0.0 1.8 1 0 0 1 1 1 0 SPOC domain V-ATPase_H_N PF03224.9 ETO28948.1 - 0.019 14.1 0.5 0.023 13.8 0.4 1.0 1 0 0 1 1 1 0 V-ATPase subunit H Secretin_N_2 PF07655.8 ETO28949.1 - 1.1 9.6 23.9 2.3 8.6 16.5 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain 5-FTHF_cyc-lig PF01812.15 ETO28950.1 - 5.3e-25 88.2 0.3 8.4e-25 87.6 0.0 1.5 2 0 0 2 2 2 1 5-formyltetrahydrofolate cyclo-ligase family DUF2678 PF10856.3 ETO28951.1 - 0.042 13.5 0.1 0.081 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) TPK_catalytic PF04263.11 ETO28951.1 - 0.094 12.3 0.1 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain LMBR1 PF04791.11 ETO28951.1 - 1.7 7.1 5.0 2.3 6.6 3.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein RP-C_C PF11800.3 ETO28951.1 - 5.5 6.6 12.0 37 3.9 7.6 2.2 1 1 0 1 1 1 0 Replication protein C C-terminal region Peptidase_M20 PF01546.23 ETO28953.1 - 2.4e-19 69.6 0.0 3.1e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 ETO28953.1 - 0.00015 21.4 0.0 0.0004 20.1 0.0 1.7 1 1 0 1 1 1 1 Peptidase dimerisation domain ABC_tran PF00005.22 ETO28954.1 - 7.8e-27 94.2 0.0 1e-26 93.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.1 ETO28954.1 - 0.00065 20.0 0.0 0.001 19.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 ETO28954.1 - 0.002 18.1 0.0 0.32 10.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 ETO28954.1 - 0.0025 16.9 0.0 0.0037 16.3 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.1 ETO28954.1 - 0.0052 16.2 0.1 0.011 15.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 ETO28954.1 - 0.008 15.3 0.1 0.016 14.4 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SRP54 PF00448.17 ETO28954.1 - 0.01 15.2 0.2 0.019 14.4 0.1 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain UPF0079 PF02367.12 ETO28954.1 - 0.027 14.1 0.1 0.048 13.3 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 ETO28954.1 - 0.044 13.3 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETO28954.1 - 0.083 12.8 0.1 0.16 11.9 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 ETO28954.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 ETO28954.1 - 0.17 11.1 0.1 5.4 6.1 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.2 ETO28955.1 - 2.8e-31 108.7 22.8 5.2e-31 107.9 15.8 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.2 ETO28955.1 - 8.7e-07 28.3 7.3 1.9e-06 27.2 5.0 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein YajC PF02699.10 ETO28955.1 - 0.28 10.9 1.7 12 5.6 0.1 2.9 2 0 0 2 2 2 0 Preprotein translocase subunit DUF4131 PF13567.1 ETO28955.1 - 2.8 7.3 11.7 0.34 10.3 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) PH PF00169.24 ETO28956.1 - 0.0033 17.5 0.3 0.0066 16.6 0.2 1.4 1 0 0 1 1 1 1 PH domain Herpes_gE PF02480.11 ETO28956.1 - 0.14 10.3 0.0 0.22 9.7 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PH_11 PF15413.1 ETO28956.1 - 0.26 11.5 1.6 0.43 10.8 0.1 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain DUF4131 PF13567.1 ETO28956.1 - 0.27 10.6 2.9 0.39 10.0 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) MBT PF02820.13 ETO28957.1 - 0.029 14.2 0.0 0.098 12.5 0.0 1.9 1 0 0 1 1 1 0 mbt repeat Tudor-knot PF11717.3 ETO28957.1 - 0.041 13.6 0.2 0.14 11.9 0.1 1.9 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain POT1 PF02765.12 ETO28958.1 - 0.00045 20.1 0.0 0.00066 19.6 0.0 1.3 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 NAD_binding_4 PF07993.7 ETO28958.1 - 0.018 13.9 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Churchill PF06573.6 ETO28959.1 - 3.5e-30 104.3 11.4 9.1e-30 102.9 7.9 1.7 1 0 0 1 1 1 1 Churchill protein TPR_11 PF13414.1 ETO28959.1 - 2.3e-17 62.3 0.6 2e-15 56.1 0.2 2.1 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETO28959.1 - 2e-10 39.8 0.5 0.00014 21.3 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO28959.1 - 4.2e-08 32.5 0.2 0.0011 18.7 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO28959.1 - 2.2e-06 27.4 0.1 0.00032 20.5 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO28959.1 - 4.7e-05 22.8 0.6 0.0017 17.9 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO28959.1 - 0.0048 17.5 0.0 0.0099 16.5 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO28959.1 - 0.0055 16.8 0.5 0.034 14.2 0.4 2.3 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 DND1_DSRM PF14709.1 ETO28959.1 - 0.028 14.7 0.0 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 FpoO PF10621.4 ETO28959.1 - 0.066 13.2 3.9 0.21 11.6 0.0 2.8 2 1 1 3 3 2 0 F420H2 dehydrogenase subunit FpoO TPR_9 PF13371.1 ETO28959.1 - 0.066 13.0 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Yippee-Mis18 PF03226.9 ETO28959.1 - 1.7 8.7 8.5 4.3 7.4 5.9 1.7 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Mito_carr PF00153.22 ETO28960.1 - 9.3e-26 89.3 0.2 4.2e-14 52.0 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein TPR_12 PF13424.1 ETO28961.1 - 3.4e-65 215.9 5.2 6e-20 70.9 0.3 4.4 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO28961.1 - 1.8e-39 131.7 27.0 2.9e-09 36.1 0.5 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_11 PF13414.1 ETO28961.1 - 2.2e-38 129.7 10.2 1.2e-13 50.4 0.3 4.7 4 1 1 5 5 5 4 TPR repeat TPR_10 PF13374.1 ETO28961.1 - 2.5e-38 128.9 0.0 4e-08 32.9 0.0 6.9 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETO28961.1 - 5.3e-34 113.3 21.9 1.5e-05 24.5 0.2 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETO28961.1 - 8.8e-34 112.7 27.4 3.6e-06 26.3 0.9 6.6 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.1 ETO28961.1 - 9.4e-34 112.5 3.3 2e-06 27.1 0.0 6.6 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.1 ETO28961.1 - 1.5e-18 65.3 6.6 0.018 15.1 0.0 6.9 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_6 PF13174.1 ETO28961.1 - 1.1e-10 41.1 8.1 0.41 11.2 0.1 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO28961.1 - 2.9e-10 40.5 0.1 0.01 16.4 0.0 4.3 2 2 2 4 4 4 3 Tetratricopeptide repeat SNAP PF14938.1 ETO28961.1 - 1.8e-09 37.1 3.9 5.8e-07 28.9 0.9 2.4 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_14 PF13428.1 ETO28961.1 - 6.8e-09 35.5 0.0 22 6.0 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat MIT PF04212.13 ETO28961.1 - 6.7e-07 29.0 8.4 0.19 11.6 0.0 5.0 4 1 0 4 4 4 2 MIT (microtubule interacting and transport) domain mit_SMPDase PF14724.1 ETO28961.1 - 0.00029 18.8 0.5 0.0085 13.9 0.0 2.3 1 1 1 2 2 2 1 Mitochondrial-associated sphingomyelin phosphodiesterase SHNi-TPR PF10516.4 ETO28961.1 - 0.00055 19.1 0.2 14 5.0 0.0 4.7 5 0 0 5 5 5 0 SHNi-TPR Apc3 PF12895.2 ETO28961.1 - 0.0013 18.8 10.5 0.61 10.2 0.0 3.3 1 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO28961.1 - 0.0061 16.8 3.1 2.4 8.5 0.0 3.9 4 1 1 5 5 4 1 Tetratricopeptide repeat DUF627 PF04781.7 ETO28961.1 - 0.0068 16.0 5.3 0.84 9.2 0.2 4.4 2 2 2 4 4 4 1 Protein of unknown function (DUF627) Cytochrom_CIII PF02085.11 ETO28961.1 - 0.085 12.9 2.9 0.39 10.8 1.0 2.3 2 0 0 2 2 2 0 Class III cytochrome C family TPR_3 PF07720.7 ETO28961.1 - 5.2 6.9 24.9 1.7 8.4 0.2 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat WD40 PF00400.27 ETO28962.1 - 1.4e-80 262.5 20.8 2.4e-13 49.3 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO28962.1 - 1.3e-09 36.7 4.9 0.045 11.8 0.2 5.2 1 1 4 5 5 5 4 Nucleoporin Nup120/160 Nbas_N PF15492.1 ETO28962.1 - 1.2e-07 31.1 2.1 0.55 9.2 0.0 4.9 1 1 4 5 5 5 2 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 ETO28962.1 - 4.1e-05 23.1 0.3 0.00017 21.1 0.0 2.0 1 1 1 2 2 2 1 PQQ-like domain Resistin PF06954.6 ETO28962.1 - 0.00012 22.3 2.4 5.8 7.2 0.1 4.4 2 2 2 4 4 4 1 Resistin Cytochrom_D1 PF02239.11 ETO28962.1 - 0.00013 20.4 0.4 0.084 11.1 0.0 2.9 1 1 3 4 4 4 2 Cytochrome D1 heme domain DPPIV_N PF00930.16 ETO28962.1 - 0.00042 19.0 0.1 0.22 10.0 0.0 3.8 3 2 1 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Proteasome_A_N PF10584.4 ETO28962.1 - 0.002 17.4 7.8 5.5 6.4 0.1 5.1 5 0 0 5 5 5 1 Proteasome subunit A N-terminal signature GSDH PF07995.6 ETO28962.1 - 0.013 14.6 0.0 0.23 10.4 0.0 2.8 3 1 0 3 3 3 0 Glucose / Sorbosone dehydrogenase Hira PF07569.6 ETO28962.1 - 0.091 11.9 2.0 7.9 5.6 0.1 4.0 2 2 3 6 6 6 0 TUP1-like enhancer of split PD40 PF07676.7 ETO28962.1 - 0.13 11.9 9.3 1.7 8.3 0.0 4.9 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat 60KD_IMP PF02096.15 ETO28963.1 - 5.9 6.5 7.6 9.4 5.8 5.2 1.2 1 0 0 1 1 1 0 60Kd inner membrane protein Pkinase PF00069.20 ETO28964.1 - 1.9e-43 148.4 0.0 2.8e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO28964.1 - 1.9e-30 105.8 0.0 3.1e-29 101.8 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO28964.1 - 9e-07 28.1 0.0 1.4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETO28964.1 - 0.0088 15.1 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YafO_toxin PF13957.1 ETO28964.1 - 0.029 14.1 0.1 0.065 13.0 0.1 1.5 1 0 0 1 1 1 0 Toxin YafO, type II toxin-antitoxin system Abhydrolase_6 PF12697.2 ETO28965.1 - 1.1e-21 77.8 0.0 3e-21 76.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETO28965.1 - 7.8e-10 38.6 0.1 9e-09 35.2 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETO28965.1 - 8.6e-10 38.5 0.0 5.3e-09 35.9 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 ETO28965.1 - 0.012 14.8 0.4 0.79 8.9 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family BAAT_C PF08840.6 ETO28965.1 - 0.026 14.2 0.2 8.2 6.0 0.0 2.7 3 0 0 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal Acyl_transf_2 PF02273.10 ETO28965.1 - 0.029 13.3 0.2 0.081 11.9 0.0 1.8 2 0 0 2 2 2 0 Acyl transferase Peptidase_S9 PF00326.16 ETO28965.1 - 0.036 13.2 0.1 0.43 9.7 0.0 2.4 3 0 0 3 3 3 0 Prolyl oligopeptidase family UPF0227 PF05728.7 ETO28965.1 - 0.064 12.9 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PhoPQ_related PF10142.4 ETO28965.1 - 0.096 11.1 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein DRMBL PF07522.9 ETO28966.1 - 4.8e-22 78.0 1.6 1.7e-20 73.1 1.1 2.5 1 1 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 ETO28966.1 - 1.9e-06 27.5 0.0 5.4e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain zf-C3HC4_3 PF13920.1 ETO28967.1 - 1.7e-12 46.8 10.7 3.6e-12 45.7 7.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO28967.1 - 2.2e-06 27.5 14.3 2.2e-06 27.5 9.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO28967.1 - 0.00028 20.5 12.2 0.00028 20.5 8.5 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 ETO28967.1 - 0.0066 16.2 10.6 0.033 14.0 7.8 1.9 2 0 0 2 2 2 1 Ring finger domain Tom37_C PF11801.3 ETO28967.1 - 0.0092 15.8 10.0 0.0092 15.8 6.9 2.2 2 0 0 2 2 2 1 Tom37 C-terminal domain DUF1281 PF06924.6 ETO28967.1 - 0.019 14.3 0.1 0.03 13.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) Prok-RING_4 PF14447.1 ETO28967.1 - 0.023 14.2 7.2 0.055 13.0 5.0 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF1510 PF07423.6 ETO28967.1 - 0.045 13.1 43.5 0.14 11.5 19.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) CobT PF06213.7 ETO28967.1 - 0.11 11.6 27.9 0.027 13.6 13.5 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT zf-P11 PF03854.9 ETO28967.1 - 0.37 10.2 6.7 0.76 9.2 4.7 1.4 1 0 0 1 1 1 0 P-11 zinc finger GEMIN8 PF15348.1 ETO28967.1 - 0.44 10.5 25.4 2 8.3 11.7 2.2 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 BUD22 PF09073.5 ETO28967.1 - 0.51 9.3 40.8 0.064 12.3 14.1 2.1 2 0 0 2 2 2 0 BUD22 Vfa1 PF08432.5 ETO28967.1 - 0.89 9.5 35.4 1.3 9.0 5.0 2.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 SAPS PF04499.10 ETO28967.1 - 1.1 7.8 22.8 2.9 6.4 10.9 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein DDHD PF02862.12 ETO28967.1 - 1.4 8.6 23.1 0.42 10.3 6.9 2.1 2 0 0 2 2 2 0 DDHD domain Daxx PF03344.10 ETO28967.1 - 4.9 5.5 40.0 0.17 10.3 19.2 2.1 2 0 0 2 2 2 0 Daxx Family DUF913 PF06025.7 ETO28967.1 - 6 5.5 12.1 10 4.7 4.9 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) SprA-related PF12118.3 ETO28967.1 - 6.2 6.0 35.1 4.2 6.6 15.9 2.1 2 0 0 2 2 2 0 SprA-related family MRP-L46 PF11788.3 ETO28967.1 - 7.2 7.3 17.1 3.6 8.2 1.3 2.4 2 0 0 2 2 2 0 39S mitochondrial ribosomal protein L46 SR-25 PF10500.4 ETO28967.1 - 8.4 5.7 30.8 0.39 10.1 5.5 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein EutH PF04346.7 ETO28968.1 - 0.012 14.5 2.7 0.013 14.4 1.9 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation protein, EutH PTS_EIIC_2 PF13303.1 ETO28968.1 - 0.03 13.1 0.5 0.043 12.6 0.3 1.3 1 0 0 1 1 1 0 Phosphotransferase system, EIIC Spore_YhaL PF14147.1 ETO28968.1 - 0.32 10.4 5.4 9.4 5.7 0.2 3.5 3 0 0 3 3 3 0 Sporulation protein YhaL Bromodomain PF00439.20 ETO28969.1 - 2.6e-25 88.1 0.0 7e-25 86.7 0.0 1.8 1 0 0 1 1 1 1 Bromodomain BRF1 PF07741.8 ETO28970.1 - 0.013 15.6 3.5 0.02 15.0 2.4 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain WASH_WAHD PF11945.3 ETO28971.1 - 9.1e-31 107.2 0.6 1.8e-30 106.2 0.4 1.4 1 1 0 1 1 1 1 WAHD domain of WASH complex MCPVI PF02993.9 ETO28971.1 - 2.7 8.0 22.1 0.22 11.6 0.4 3.1 3 0 0 3 3 3 0 Minor capsid protein VI Cation_ATPase_C PF00689.16 ETO28972.1 - 1.2e-37 129.1 6.9 1.2e-37 129.1 4.8 2.6 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 ETO28972.1 - 3.4e-33 115.8 0.0 7.6e-32 111.4 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 ETO28972.1 - 2.3e-28 98.8 0.3 4.8e-28 97.7 0.2 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 ETO28972.1 - 2.4e-15 57.2 0.4 1.6e-14 54.5 0.3 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETO28972.1 - 1.1e-14 54.1 0.0 2.2e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 ETO28972.1 - 4.7e-06 26.3 6.5 0.0012 18.4 1.0 2.7 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase ubiquitin PF00240.18 ETO28972.1 - 0.0038 16.5 0.0 0.0089 15.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family HAD_2 PF13419.1 ETO28972.1 - 0.013 15.7 0.0 0.035 14.3 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 ETO28972.1 - 0.031 14.1 0.0 0.09 12.6 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase MreB_Mbl PF06723.8 ETO28973.1 - 0.039 12.5 1.0 3 6.3 0.0 2.6 3 0 0 3 3 3 0 MreB/Mbl protein Ank PF00023.25 ETO28974.1 - 2.8e-08 33.1 0.1 7.1e-08 31.8 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ammonium_transp PF00909.16 ETO28974.1 - 2.2e-07 29.6 0.0 2.6e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Ank_2 PF12796.2 ETO28974.1 - 2.4e-05 24.6 0.0 2.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO28974.1 - 3.2e-05 23.7 0.1 8.1e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.1 ETO28974.1 - 0.00081 19.5 0.1 0.002 18.2 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO28974.1 - 0.0022 18.4 0.2 0.0052 17.2 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (many copies) XK-related PF09815.4 ETO28976.1 - 0.0079 15.2 32.1 0.22 10.5 22.3 3.0 1 1 0 1 1 1 1 XK-related protein Tir_receptor_C PF07489.6 ETO28976.1 - 0.24 11.1 3.0 0.34 10.6 2.1 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus DUF2457 PF10446.4 ETO28977.1 - 0.0033 16.2 12.6 0.0033 16.2 8.7 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) Myc_N PF01056.13 ETO28977.1 - 0.025 13.7 1.1 0.04 13.0 0.7 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Med3 PF11593.3 ETO28977.1 - 0.037 13.2 3.3 0.057 12.6 2.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Sigma70_ner PF04546.8 ETO28977.1 - 0.12 11.9 8.0 0.28 10.7 5.5 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 ETO28977.1 - 0.14 10.1 6.3 0.24 9.3 4.4 1.3 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.1 ETO28977.1 - 0.39 11.0 21.6 0.056 13.7 11.0 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.7 ETO28977.1 - 0.87 9.2 17.1 0.02 14.6 5.9 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.6 ETO28977.1 - 1.4 8.6 10.1 3.4 7.4 7.0 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Cnd2 PF05786.9 ETO28977.1 - 1.7 7.0 13.3 0.011 14.3 1.7 2.0 2 0 0 2 2 2 0 Condensin complex subunit 2 Tom22 PF04281.8 ETO28977.1 - 2.1 7.8 8.5 4.9 6.6 5.9 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 FAM176 PF14851.1 ETO28977.1 - 3.1 7.4 7.7 1.2 8.7 3.0 2.0 2 0 0 2 2 2 0 FAM176 family Glu_synthase PF01645.12 ETO28977.1 - 3.8 6.3 6.3 0.26 10.1 0.7 1.7 2 0 0 2 2 2 0 Conserved region in glutamate synthase NOA36 PF06524.7 ETO28977.1 - 5.8 6.0 16.1 9.9 5.3 11.1 1.3 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 ETO28977.1 - 7.9 4.2 16.3 0.49 8.2 7.6 1.6 2 0 0 2 2 2 0 Nop14-like family Nucleoplasmin PF03066.10 ETO28977.1 - 9.8 5.6 18.5 18 4.8 12.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin Glyco_hydro_53 PF07745.8 ETO28983.1 - 6.1e-22 77.8 0.0 7.1e-22 77.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Dicty_REP PF05086.7 ETO28984.1 - 0.0036 15.1 4.6 0.0042 14.9 3.2 1.0 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 ETO28984.1 - 0.033 13.9 2.4 0.051 13.3 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Tir_receptor_C PF07489.6 ETO28984.1 - 0.12 12.1 2.7 0.15 11.8 1.9 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus SSP160 PF06933.6 ETO28984.1 - 2.9 5.7 5.3 3.7 5.4 3.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Vfa1 PF08432.5 ETO28985.1 - 0.32 10.9 24.8 0.58 10.1 4.8 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF1754 PF08555.5 ETO28985.1 - 0.96 10.0 27.8 0.065 13.8 3.4 2.4 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) DUF1510 PF07423.6 ETO28985.1 - 1.9 7.8 24.6 0.38 10.1 4.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) RNA_pol_Rpc4 PF05132.9 ETO28985.1 - 5.5 6.9 11.7 0.96 9.4 0.8 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 Rtf2 PF04641.7 ETO28985.1 - 6.4 5.8 22.6 0.69 9.0 3.1 2.2 2 0 0 2 2 2 0 Rtf2 RING-finger OSTbeta PF15048.1 ETO28985.1 - 7.8 6.5 7.9 0.45 10.5 1.1 2.1 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein DUF2594 PF10769.4 ETO28986.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2594) SART-1 PF03343.8 ETO28988.1 - 0.002 16.5 18.2 0.0026 16.1 12.6 1.1 1 0 0 1 1 1 1 SART-1 family TFIIF_alpha PF05793.7 ETO28988.1 - 0.011 14.1 26.0 0.014 13.8 18.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Daxx PF03344.10 ETO28988.1 - 0.033 12.6 14.2 0.039 12.4 9.8 1.2 1 0 0 1 1 1 0 Daxx Family CDC27 PF09507.5 ETO28988.1 - 0.038 13.2 20.8 0.054 12.7 14.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 BUD22 PF09073.5 ETO28988.1 - 0.047 12.7 20.9 0.06 12.4 14.5 1.2 1 0 0 1 1 1 0 BUD22 Vfa1 PF08432.5 ETO28988.1 - 0.11 12.5 18.2 0.2 11.6 12.6 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TT_ORF2 PF02957.10 ETO28988.1 - 0.12 13.0 9.9 0.24 12.1 6.8 1.4 1 0 0 1 1 1 0 TT viral ORF2 DUF1510 PF07423.6 ETO28988.1 - 0.14 11.4 18.5 0.21 10.9 12.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FLO_LFY PF01698.11 ETO28988.1 - 0.15 10.8 13.4 0.21 10.4 9.3 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Nop14 PF04147.7 ETO28988.1 - 0.16 9.8 19.9 0.21 9.4 13.8 1.1 1 0 0 1 1 1 0 Nop14-like family Dicty_REP PF05086.7 ETO28988.1 - 0.17 9.5 13.9 0.23 9.1 9.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Cwf_Cwc_15 PF04889.7 ETO28988.1 - 0.21 11.2 21.8 0.33 10.6 15.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.3 ETO28988.1 - 0.23 11.3 23.2 0.38 10.6 16.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Pox_Ag35 PF03286.9 ETO28988.1 - 0.4 10.1 16.2 0.63 9.5 11.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FYDLN_acid PF09538.5 ETO28988.1 - 0.88 10.1 21.1 1.8 9.1 14.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF1168 PF06658.7 ETO28988.1 - 1.2 8.7 22.3 2.1 7.8 15.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) BTV_NS2 PF04514.7 ETO28988.1 - 2 7.1 13.6 2.9 6.7 9.4 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF2457 PF10446.4 ETO28988.1 - 2.2 6.9 32.0 2 7.0 21.4 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2457) CKAP2_C PF15297.1 ETO28988.1 - 2.5 6.8 13.1 3.7 6.2 9.0 1.2 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus PBP_sp32 PF07222.7 ETO28988.1 - 5.6 6.0 11.2 9.9 5.2 7.8 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Atrophin-1 PF03154.10 ETO28988.1 - 9.8 4.1 15.7 12 3.8 10.9 1.1 1 0 0 1 1 1 0 Atrophin-1 family Nnf1 PF03980.9 ETO28989.1 - 0.017 15.0 1.8 0.026 14.5 0.6 1.8 2 0 0 2 2 2 0 Nnf1 Metallophos PF00149.23 ETO28989.1 - 0.24 10.7 2.4 0.64 9.3 1.6 1.7 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase CAP_GLY PF01302.20 ETO28990.1 - 6.1e-23 80.3 0.6 3.6e-15 55.4 0.2 2.9 2 1 0 2 2 2 2 CAP-Gly domain Mucin PF01456.12 ETO28990.1 - 0.19 11.4 25.4 0.34 10.6 17.6 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.7 ETO28990.1 - 0.66 7.6 8.5 0.98 7.0 5.9 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pex14_N PF04695.8 ETO28990.1 - 1 9.3 6.0 2.3 8.2 4.2 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CobT PF06213.7 ETO28991.1 - 0.077 12.1 13.0 0.13 11.3 9.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2457 PF10446.4 ETO28991.1 - 1.8 7.2 22.0 3.5 6.2 15.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) UDG PF03167.14 ETO28995.1 - 8.1e-24 83.8 0.0 1.4e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily His_Phos_1 PF00300.17 ETO28997.1 - 2.6e-12 47.1 0.0 4.1e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) P-mevalo_kinase PF04275.9 ETO28998.1 - 0.0048 16.6 3.0 0.064 12.9 0.2 2.4 2 0 0 2 2 2 2 Phosphomevalonate kinase rve_2 PF13333.1 ETO28998.1 - 0.078 13.0 1.5 0.14 12.2 0.2 2.0 2 0 0 2 2 2 0 Integrase core domain Prok-RING_1 PF14446.1 ETO29000.1 - 0.0034 17.0 16.3 0.0037 16.9 2.0 3.2 2 1 1 3 3 3 2 Prokaryotic RING finger family 1 PH_4 PF15404.1 ETO29000.1 - 0.14 11.7 2.7 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain FpoO PF10621.4 ETO29000.1 - 0.23 11.5 6.2 0.7 9.9 4.3 1.9 1 1 0 1 1 1 0 F420H2 dehydrogenase subunit FpoO ZZ PF00569.12 ETO29000.1 - 0.43 10.1 18.5 0.18 11.3 1.6 3.3 2 2 0 2 2 2 0 Zinc finger, ZZ type LANC_like PF05147.8 ETO29001.1 - 2.8e-35 121.5 1.0 3e-35 121.4 0.7 1.0 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein Kelch_6 PF13964.1 ETO29002.1 - 1.5e-07 31.2 7.0 0.012 15.7 0.1 4.6 3 2 2 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO29002.1 - 1.4e-06 27.7 2.7 0.0021 17.5 0.1 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO29002.1 - 5.1e-06 26.4 0.0 0.0049 17.0 0.0 3.5 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO29002.1 - 1.7e-05 24.6 3.2 0.12 12.3 0.1 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO29002.1 - 0.026 14.3 4.0 0.58 9.9 0.0 3.8 3 1 1 4 4 4 0 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO29002.1 - 0.038 13.7 3.0 20 5.1 0.1 4.3 5 0 0 5 5 5 0 Kelch motif WD40 PF00400.27 ETO29003.1 - 2.6e-75 245.8 17.6 1.8e-11 43.4 0.1 7.0 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO29003.1 - 9e-06 24.1 9.4 0.003 15.7 0.5 4.5 1 1 3 5 5 5 3 Nucleoporin Nup120/160 Resistin PF06954.6 ETO29003.1 - 0.00044 20.4 0.1 12 6.2 0.0 4.1 2 1 1 4 4 4 1 Resistin DUF1258 PF06869.7 ETO29003.1 - 0.0014 17.7 0.3 0.25 10.4 0.0 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF1258) Cytochrom_D1 PF02239.11 ETO29003.1 - 0.0038 15.5 1.2 0.24 9.6 0.3 2.6 1 1 2 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO29003.1 - 0.089 11.5 6.5 0.52 9.0 0.3 3.4 2 2 2 4 4 4 0 Nup133 N terminal like PD40 PF07676.7 ETO29003.1 - 0.092 12.4 1.9 58 3.5 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 ETO29004.1 - 2.2e-65 214.3 23.4 1e-12 47.4 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO29004.1 - 7.3e-07 27.7 1.5 0.84 7.6 0.0 4.8 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO29004.1 - 1.9e-05 23.5 8.5 0.12 11.1 0.5 4.7 1 1 2 4 4 4 2 Nup133 N terminal like Nbas_N PF15492.1 ETO29004.1 - 0.00021 20.5 1.1 0.039 13.0 0.1 2.9 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 ETO29004.1 - 0.00054 18.3 0.0 0.31 9.2 0.0 2.6 1 1 0 2 2 2 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO29004.1 - 0.0033 16.9 0.0 0.029 13.8 0.0 2.3 1 1 1 2 2 2 1 PQQ-like domain DUF4221 PF13970.1 ETO29004.1 - 0.015 14.6 0.6 0.32 10.2 0.0 2.9 2 1 2 4 4 4 0 Domain of unknown function (DUF4221) PQQ PF01011.16 ETO29004.1 - 0.061 12.8 0.1 1.8 8.2 0.0 3.1 3 0 0 3 3 3 0 PQQ enzyme repeat Clathrin_propel PF01394.15 ETO29004.1 - 0.073 13.3 0.4 11 6.5 0.1 3.1 2 0 0 2 2 2 0 Clathrin propeller repeat IKI3 PF04762.7 ETO29004.1 - 0.099 10.4 0.0 0.66 7.7 0.0 2.0 1 1 2 3 3 3 0 IKI3 family RicinB_lectin_2 PF14200.1 ETO29004.1 - 0.11 12.8 0.2 0.37 11.1 0.0 2.0 2 0 0 2 2 1 0 Ricin-type beta-trefoil lectin domain-like PD40 PF07676.7 ETO29004.1 - 0.16 11.6 0.9 18 5.0 0.0 3.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Pkinase PF00069.20 ETO29005.1 - 1.8e-69 233.8 0.0 2.2e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO29005.1 - 9.1e-42 142.9 0.0 1.2e-41 142.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO29005.1 - 3.7e-09 35.9 0.0 1.9e-08 33.6 0.0 2.0 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 ETO29005.1 - 0.00024 20.9 0.0 0.0004 20.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 ETO29005.1 - 0.0033 16.5 0.0 0.018 14.1 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APP_E2 PF12925.2 ETO29005.1 - 0.059 12.9 0.1 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein DUF3439 PF11921.3 ETO29005.1 - 0.73 9.6 11.6 0.24 11.1 6.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 ETO29005.1 - 0.84 7.3 11.4 1.2 6.8 7.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.6 ETO29005.1 - 1.7 6.5 13.5 2.5 5.9 9.3 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.12 ETO29005.1 - 2.4 7.9 18.9 3.8 7.2 13.1 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Pkinase PF00069.20 ETO29006.1 - 5.3e-50 169.9 0.0 6.1e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO29006.1 - 1.4e-31 109.5 0.0 1.7e-31 109.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO29006.1 - 1.4e-05 24.2 0.0 2.4e-05 23.4 0.0 1.3 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 ETO29006.1 - 9.3e-05 22.2 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 ETO29006.1 - 0.0034 16.4 0.0 0.0059 15.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 ETO29006.1 - 0.048 12.9 0.0 0.085 12.1 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.6 ETO29006.1 - 0.079 11.7 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 YukC PF10140.4 ETO29006.1 - 0.16 10.5 0.0 0.2 10.1 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Pkinase PF00069.20 ETO29007.1 - 0.00016 20.8 0.0 0.00024 20.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APP_E2 PF12925.2 ETO29007.1 - 0.008 15.7 0.1 0.0099 15.4 0.0 1.2 1 0 0 1 1 1 1 E2 domain of amyloid precursor protein Activator_LAG-3 PF11498.3 ETO29007.1 - 0.035 12.8 0.2 0.043 12.5 0.1 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Dicty_REP PF05086.7 ETO29007.1 - 2.6 5.6 6.9 2.9 5.5 4.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.6 ETO29007.1 - 6.4 4.6 7.7 7.5 4.3 5.4 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Metallophos_C PF14008.1 ETO29008.1 - 1.1e-07 31.8 6.8 3.1e-06 27.1 3.3 2.8 2 1 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.23 ETO29008.1 - 0.00074 18.9 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Nol1_Nop2_Fmu PF01189.12 ETO29010.1 - 4.4e-80 269.0 0.0 1.9e-79 266.9 0.0 2.0 2 0 0 2 2 2 1 NOL1/NOP2/sun family Abhydrolase_5 PF12695.2 ETO29010.1 - 2.1e-08 34.0 0.0 3.6e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_31 PF13847.1 ETO29010.1 - 0.00035 20.2 0.0 0.0011 18.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_6 PF12697.2 ETO29010.1 - 0.00054 19.9 0.0 0.16 11.8 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Methyltransf_26 PF13659.1 ETO29010.1 - 0.00081 19.4 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 ETO29010.1 - 0.00084 19.3 0.0 0.002 18.1 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.14 ETO29010.1 - 0.0026 17.3 0.0 0.035 13.6 0.0 2.3 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Abhydrolase_3 PF07859.8 ETO29010.1 - 0.0046 16.5 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold MTS PF05175.9 ETO29010.1 - 0.0079 15.5 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Peptidase_S15 PF02129.13 ETO29010.1 - 0.029 13.7 0.0 0.029 13.7 0.0 2.2 3 0 0 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) 2-Hacid_dh_C PF02826.14 ETO29011.1 - 6.1e-41 139.5 0.1 9.3e-41 138.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 ETO29011.1 - 1.8e-23 82.4 0.3 2.7e-23 81.9 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 ETO29011.1 - 6.6e-09 35.8 0.1 1.3e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.1 ETO29011.1 - 0.058 13.3 0.6 0.27 11.1 0.1 2.1 2 0 0 2 2 2 0 NADH(P)-binding MFS_1 PF07690.11 ETO29012.1 - 8e-12 44.5 17.4 1.6e-10 40.2 4.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETO29012.1 - 1.3e-07 30.3 1.8 1.6e-07 30.1 1.3 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein Sugar_tr PF00083.19 ETO29012.1 - 0.0081 14.7 7.7 0.011 14.3 5.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1765 PF08578.5 ETO29015.1 - 7.1e-07 29.3 7.8 8.9e-05 22.5 5.4 3.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1765) DUF4132 PF13569.1 ETO29015.1 - 0.02 14.3 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4132) DUF4064 PF13273.1 ETO29015.1 - 0.036 14.1 0.0 0.091 12.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) ABC2_membrane_2 PF12679.2 ETO29015.1 - 0.061 12.1 0.3 0.089 11.6 0.2 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein PAXNEB PF05625.6 ETO29015.1 - 0.07 11.9 0.1 0.36 9.6 0.1 1.9 2 0 0 2 2 2 0 PAXNEB protein ARL2_Bind_BART PF11527.3 ETO29015.1 - 0.26 11.1 3.5 0.38 10.5 1.3 2.3 2 1 0 2 2 2 0 The ARF-like 2 binding protein BART ABC2_membrane PF01061.19 ETO29016.1 - 5.1e-42 143.4 26.7 6.6e-42 143.0 18.5 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 ETO29016.1 - 3.2e-08 32.9 20.7 3.2e-08 32.9 14.4 1.8 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.2 ETO29016.1 - 0.018 13.9 15.6 0.8 8.5 10.8 2.2 1 1 0 1 1 1 0 ABC-2 family transporter protein Claudin_2 PF13903.1 ETO29016.1 - 7.2 6.2 18.8 0.12 12.1 1.1 3.0 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction PH PF00169.24 ETO29017.1 - 2.9e-09 37.0 5.6 7.6e-09 35.7 3.9 1.7 1 1 0 1 1 1 1 PH domain PH_3 PF14593.1 ETO29017.1 - 2.1e-08 33.9 3.3 2.1e-08 33.9 2.3 2.9 2 1 1 3 3 3 1 PH domain PH_11 PF15413.1 ETO29017.1 - 1.5e-07 31.6 2.6 2.7e-07 30.8 1.8 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 ETO29017.1 - 0.052 13.6 3.4 0.3 11.1 0.2 2.4 1 1 1 2 2 2 0 Pleckstrin homology domain PX PF00787.19 ETO29018.1 - 0.057 13.2 1.9 0.12 12.1 1.3 1.5 1 0 0 1 1 1 0 PX domain Sec6 PF06046.8 ETO29019.1 - 0.00011 20.5 0.5 0.00016 19.8 0.4 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 TilS PF09179.6 ETO29019.1 - 0.17 11.8 0.6 0.72 9.9 0.0 2.1 2 0 0 2 2 2 0 TilS substrate binding domain Ion_trans PF00520.26 ETO29020.1 - 9.6e-15 54.3 50.4 2.6e-07 30.1 8.5 4.3 3 1 0 3 3 3 2 Ion transport protein cNMP_binding PF00027.24 ETO29020.1 - 1.2e-11 44.2 0.0 1.8e-05 24.4 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain EF-hand_8 PF13833.1 ETO29020.1 - 0.00015 21.3 1.2 0.02 14.5 0.0 3.9 4 0 0 4 4 4 1 EF-hand domain pair DEP PF00610.16 ETO29020.1 - 0.00034 20.3 0.0 0.001 18.7 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) EF-hand_1 PF00036.27 ETO29020.1 - 0.027 13.7 0.0 0.18 11.2 0.0 2.6 2 0 0 2 2 2 0 EF hand Orbi_VP5 PF00901.12 ETO29020.1 - 0.042 12.0 0.1 0.088 11.0 0.0 1.4 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Peptidase_M16_C PF05193.16 ETO29022.1 - 0.0006 19.5 0.0 0.0015 18.2 0.0 1.7 1 1 0 1 1 1 1 Peptidase M16 inactive domain Nbl1_Borealin_N PF10444.4 ETO29022.1 - 0.015 14.6 0.3 0.026 13.8 0.2 1.4 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal priB_priC PF07445.7 ETO29023.1 - 0.11 11.9 0.2 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 Primosomal replication protein priB and priC DUF4131 PF13567.1 ETO29024.1 - 0.16 11.3 2.2 0.34 10.2 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Abhydrolase_5 PF12695.2 ETO29025.1 - 8e-18 64.5 0.0 2.3e-17 63.0 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETO29025.1 - 3.2e-10 40.2 0.0 2.9e-09 37.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 ETO29025.1 - 1.6e-06 27.6 0.6 0.00033 20.1 0.0 3.2 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 ETO29025.1 - 5e-06 26.2 0.0 0.0031 17.1 0.0 2.4 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETO29025.1 - 6.9e-05 22.1 0.0 0.00019 20.7 0.0 1.7 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 ETO29025.1 - 8.1e-05 22.2 0.0 0.00016 21.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.7 ETO29025.1 - 0.0029 16.1 0.0 0.81 8.1 0.0 2.3 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) DLH PF01738.13 ETO29025.1 - 0.0038 16.5 0.0 0.053 12.7 0.0 2.3 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.6 ETO29025.1 - 0.043 13.5 0.0 1.8 8.2 0.0 2.6 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_9 PF10081.4 ETO29025.1 - 0.048 12.3 0.0 0.074 11.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Me-amine-dh_H PF06433.6 ETO29026.1 - 0.026 13.1 0.1 0.026 13.1 0.1 1.1 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) DUF1279 PF06916.8 ETO29026.1 - 0.065 13.5 0.4 0.092 13.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) Menin PF05053.8 ETO29027.1 - 0.57 8.2 9.8 0.68 8.0 6.8 1.1 1 0 0 1 1 1 0 Menin AhpC-TSA PF00578.16 ETO29029.1 - 1.6e-20 73.0 0.0 2.7e-16 59.3 0.0 2.2 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 ETO29029.1 - 4e-08 32.9 0.0 2.1e-07 30.5 0.0 1.9 1 1 0 1 1 1 1 Redoxin PUF PF00806.14 ETO29030.1 - 4.4e-21 73.1 8.6 4.8e-06 25.7 0.0 7.1 7 0 0 7 7 7 5 Pumilio-family RNA binding repeat FHA PF00498.21 ETO29031.1 - 1.8e-12 47.2 0.2 2.5e-12 46.6 0.2 1.3 1 0 0 1 1 1 1 FHA domain TATR PF03430.8 ETO29033.1 - 0.0052 15.4 1.6 0.0055 15.4 1.1 1.1 1 0 0 1 1 1 1 Trans-activating transcriptional regulator DUF2040 PF09745.4 ETO29033.1 - 0.24 11.2 7.9 0.67 9.7 0.8 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 55 (DUF2040) DUF3602 PF12223.3 ETO29033.1 - 0.85 10.0 3.2 1.3 9.4 2.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3602) ETRAMP PF09716.5 ETO29033.1 - 1.7 8.6 7.0 1.1 9.2 3.5 1.7 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF3435 PF11917.3 ETO29033.1 - 4 6.0 6.9 11 4.5 4.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3435) NESP55 PF06390.7 ETO29034.1 - 0.075 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) DUF2845 PF11006.3 ETO29034.1 - 0.096 12.5 1.2 0.28 11.0 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2845) Secretin_N_2 PF07655.8 ETO29035.1 - 0.34 11.3 20.7 0.7 10.3 7.9 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain Pneumo_att_G PF05539.6 ETO29037.1 - 0.36 10.1 9.5 0.45 9.8 6.6 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Tim17 PF02466.14 ETO29038.1 - 1.8e-20 73.2 7.6 3e-20 72.5 5.3 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family 7tm_3 PF00003.17 ETO29040.1 - 8.2e-11 41.6 25.0 8.2e-11 41.6 17.3 2.4 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR adh_short PF00106.20 ETO29041.1 - 1.6e-25 89.9 0.0 5e-25 88.3 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETO29041.1 - 1.6e-24 87.0 0.1 6.6e-24 85.0 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETO29041.1 - 6.8e-09 35.6 0.0 1.6e-08 34.4 0.0 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ETO29041.1 - 0.01 15.8 0.2 0.065 13.2 0.0 2.1 2 1 1 3 3 3 0 NADH(P)-binding Epimerase PF01370.16 ETO29041.1 - 0.024 14.0 0.3 0.13 11.6 0.2 2.4 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ETO29041.1 - 0.056 12.3 0.2 0.099 11.5 0.1 1.4 1 1 0 1 1 1 0 Male sterility protein 3HCDH_N PF02737.13 ETO29041.1 - 0.08 12.5 0.3 0.31 10.6 0.2 1.9 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Mito_fiss_reg PF05308.6 ETO29042.1 - 0.23 10.7 5.1 0.48 9.7 3.5 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator CRAL_TRIO_2 PF13716.1 ETO29043.1 - 0.02 14.7 1.3 0.029 14.2 0.9 1.2 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Pkinase PF00069.20 ETO29045.1 - 6.5e-68 228.6 1.2 7.9e-68 228.4 0.9 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO29045.1 - 2.1e-38 131.9 1.2 2.2e-37 128.5 0.8 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO29045.1 - 5.2e-06 25.6 0.3 0.00058 18.9 0.2 2.5 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 ETO29045.1 - 0.0023 17.0 0.6 0.0046 16.0 0.4 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO29045.1 - 0.011 15.4 0.4 0.02 14.6 0.3 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Secretin_N_2 PF07655.8 ETO29045.1 - 0.54 10.6 8.4 1.3 9.4 5.9 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain DnaJ PF00226.26 ETO29046.1 - 3.8e-17 61.7 0.7 7.6e-17 60.8 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain Kelch_6 PF13964.1 ETO29049.1 - 1.4e-07 31.3 3.2 1.2e-06 28.4 0.2 3.5 3 1 1 4 4 4 1 Kelch motif Kelch_1 PF01344.20 ETO29049.1 - 2e-06 27.2 3.1 1.7e-05 24.2 0.8 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO29049.1 - 0.00013 21.5 2.7 0.00062 19.4 0.2 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETO29049.1 - 0.00022 20.9 0.3 0.0013 18.4 0.1 2.5 2 1 0 2 2 2 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO29049.1 - 0.00032 20.7 0.1 0.001 19.1 0.0 1.9 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO29049.1 - 0.00055 19.8 1.5 0.0028 17.5 1.0 2.3 2 0 0 2 2 2 1 Kelch motif WD40 PF00400.27 ETO29051.1 - 1.9e-116 376.2 50.3 1.5e-11 43.7 0.1 14.5 14 0 0 14 14 14 13 WD domain, G-beta repeat NACHT PF05729.7 ETO29051.1 - 6.8e-10 38.8 0.0 2.2e-09 37.1 0.0 2.0 1 0 0 1 1 1 1 NACHT domain Nup160 PF11715.3 ETO29051.1 - 1.5e-09 36.5 26.6 0.32 9.0 1.2 10.8 1 1 9 10 10 10 5 Nucleoporin Nup120/160 AAA_22 PF13401.1 ETO29051.1 - 3.8e-06 27.0 0.2 2.6e-05 24.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Pentapeptide_4 PF13599.1 ETO29051.1 - 4.5e-05 23.1 3.0 4.5e-05 23.1 2.1 2.9 3 0 0 3 3 3 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETO29051.1 - 0.0001 21.4 2.9 0.00024 20.2 2.0 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 ETO29051.1 - 0.00032 20.5 3.1 0.0024 17.7 2.5 2.4 1 1 1 2 2 2 1 Pentapeptide repeats (9 copies) AAA_18 PF13238.1 ETO29051.1 - 0.00038 20.7 4.2 0.00045 20.5 0.1 3.3 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 ETO29051.1 - 0.0013 19.5 0.1 0.018 15.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain Cytochrom_D1 PF02239.11 ETO29051.1 - 0.002 16.4 12.2 0.21 9.8 0.0 4.9 4 1 1 6 6 6 2 Cytochrome D1 heme domain DUF1652 PF07865.6 ETO29051.1 - 0.013 15.0 0.1 9.2 5.9 0.0 5.5 6 1 1 7 7 7 0 Protein of unknown function (DUF1652) CUE PF02845.11 ETO29051.1 - 0.071 12.6 0.1 0.071 12.6 0.1 2.7 3 0 0 3 3 3 0 CUE domain PD40 PF07676.7 ETO29051.1 - 0.14 11.8 14.4 3 7.5 0.1 6.5 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 ETO29051.1 - 0.53 9.6 5.5 92 2.4 0.0 5.7 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 ETO29052.1 - 3.6e-43 143.9 14.2 2.5e-10 39.8 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO29052.1 - 4.7e-10 39.4 0.0 0.0027 17.4 0.0 3.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 ETO29052.1 - 3.4e-05 22.7 4.3 0.0034 16.1 1.3 2.8 1 1 1 2 2 2 2 Nup133 N terminal like PD40 PF07676.7 ETO29052.1 - 0.0014 18.2 1.1 1.8 8.2 0.0 4.7 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO29052.1 - 0.0072 14.6 0.4 0.36 9.0 0.1 2.5 1 1 0 2 2 2 1 Cytochrome D1 heme domain IKI3 PF04762.7 ETO29052.1 - 0.011 13.6 1.0 1.2 6.8 0.0 2.6 2 1 1 3 3 3 0 IKI3 family Ricin_B_lectin PF00652.17 ETO29052.1 - 0.091 12.7 0.1 3.5 7.6 0.0 2.7 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain CNP1 PF08750.6 ETO29052.1 - 0.093 12.4 0.0 0.26 10.9 0.0 1.7 2 0 0 2 2 2 0 CNP1-like family Proteasome_A_N PF10584.4 ETO29052.1 - 0.99 8.7 7.0 2.1 7.7 0.1 3.5 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature FlxA PF14282.1 ETO29053.1 - 0.0037 17.2 13.9 0.0037 17.2 9.6 1.9 1 1 1 2 2 2 1 FlxA-like protein IncA PF04156.9 ETO29053.1 - 0.0045 16.6 8.1 0.0058 16.2 5.6 1.2 1 0 0 1 1 1 1 IncA protein LUC7 PF03194.10 ETO29053.1 - 0.0056 16.2 6.8 0.0065 16.0 4.7 1.1 1 0 0 1 1 1 1 LUC7 N_terminus V_ATPase_I PF01496.14 ETO29053.1 - 0.0095 13.8 8.2 0.0097 13.8 5.7 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Tropomyosin_1 PF12718.2 ETO29053.1 - 0.013 15.3 10.6 0.013 15.3 7.4 1.8 1 1 1 2 2 2 0 Tropomyosin like Nup54 PF13874.1 ETO29053.1 - 0.015 14.9 8.1 0.02 14.5 5.6 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 PAXNEB PF05625.6 ETO29053.1 - 0.021 13.6 7.9 0.022 13.5 5.5 1.0 1 0 0 1 1 1 0 PAXNEB protein APG6 PF04111.7 ETO29053.1 - 0.027 13.5 13.4 0.03 13.3 9.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 CDC45 PF02724.9 ETO29053.1 - 0.033 12.2 11.4 0.037 12.0 7.9 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF3450 PF11932.3 ETO29053.1 - 0.036 13.3 8.6 0.044 13.0 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Sigma70_ner PF04546.8 ETO29053.1 - 0.037 13.6 8.7 0.046 13.3 6.1 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region HALZ PF02183.13 ETO29053.1 - 0.062 13.0 0.8 0.062 13.0 0.6 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF342 PF03961.8 ETO29053.1 - 0.08 11.3 6.0 0.091 11.1 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF812 PF05667.6 ETO29053.1 - 0.093 11.2 11.6 0.11 11.0 8.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DNA_repr_REX1B PF14966.1 ETO29053.1 - 0.096 13.0 3.5 0.14 12.5 2.4 1.2 1 0 0 1 1 1 0 DNA repair REX1-B zf-Di19 PF05605.7 ETO29053.1 - 0.099 12.7 1.9 0.16 12.0 1.3 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF1835 PF08874.5 ETO29053.1 - 0.099 12.5 4.4 0.14 12.1 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) TarH PF02203.10 ETO29053.1 - 0.11 12.3 5.4 0.15 11.8 3.7 1.2 1 0 0 1 1 1 0 Tar ligand binding domain homologue T2SM PF04612.7 ETO29053.1 - 0.13 11.9 2.9 0.25 11.1 2.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Phage_lysis PF03245.8 ETO29053.1 - 0.18 11.7 4.4 0.28 11.1 3.0 1.4 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein Cupin_8 PF13621.1 ETO29053.1 - 0.19 11.2 9.4 0.22 10.9 6.5 1.1 1 0 0 1 1 1 0 Cupin-like domain PRK PF00485.13 ETO29053.1 - 0.2 11.1 2.5 0.22 11.0 1.8 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF506 PF04720.7 ETO29053.1 - 0.21 11.1 7.8 0.3 10.6 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Pro_CA PF00484.14 ETO29053.1 - 0.22 11.4 5.7 0.18 11.7 3.2 1.3 1 1 0 1 1 1 0 Carbonic anhydrase PA26 PF04636.8 ETO29053.1 - 0.23 10.0 9.4 0.25 10.0 6.5 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Daxx PF03344.10 ETO29053.1 - 0.38 9.1 13.7 0.43 9.0 9.5 1.0 1 0 0 1 1 1 0 Daxx Family Phage_GPO PF05929.6 ETO29053.1 - 0.52 9.5 4.6 0.59 9.3 3.2 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase NPV_P10 PF05531.7 ETO29053.1 - 1.1 9.5 5.5 10 6.4 0.2 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3573 PF12097.3 ETO29053.1 - 1.4 7.4 6.7 1.7 7.1 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Adaptin_binding PF10199.4 ETO29053.1 - 1.4 9.2 16.0 2.1 8.6 11.1 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 CCDC-167 PF15188.1 ETO29053.1 - 2.2 8.2 7.7 9.7 6.2 5.3 2.0 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Mitochondr_Som1 PF11093.3 ETO29053.1 - 2.3 8.0 5.0 1.5 8.6 2.0 1.8 1 1 1 2 2 2 0 Mitochondrial export protein Som1 DivIC PF04977.10 ETO29053.1 - 3.4 7.2 6.8 5.1 6.6 3.2 2.3 1 1 1 2 2 2 0 Septum formation initiator Sigma_reg_C PF13791.1 ETO29053.1 - 4 7.4 16.6 5.6 6.9 10.7 1.7 1 1 1 2 2 2 0 Sigma factor regulator C-terminal DUF4315 PF14193.1 ETO29053.1 - 4.7 7.2 14.5 0.12 12.3 4.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4315) Seryl_tRNA_N PF02403.17 ETO29053.1 - 5.2 7.1 14.4 0.2 11.6 4.8 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.1 ETO29053.1 - 5.6 5.8 8.3 3.4 6.5 4.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) zf-H2C2_2 PF13465.1 ETO29054.1 - 5.5e-05 23.2 3.3 5.5e-05 23.2 2.3 4.1 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 ETO29054.1 - 0.0048 17.1 5.6 0.0048 17.1 3.9 3.4 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETO29054.1 - 0.57 10.6 22.0 0.2 12.0 2.0 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger HI0933_like PF03486.9 ETO29055.1 - 0.0052 15.3 5.5 0.0071 14.8 3.8 1.1 1 0 0 1 1 1 1 HI0933-like protein DUF4414 PF14377.1 ETO29055.1 - 0.19 11.6 2.7 0.3 10.9 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4414) DUF342 PF03961.8 ETO29055.1 - 0.51 8.6 10.9 0.59 8.4 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) NOC3p PF07540.6 ETO29055.1 - 2.6 8.3 8.3 1.1 9.6 1.7 2.4 1 1 1 2 2 2 0 Nucleolar complex-associated protein zf-UBR PF02207.15 ETO29058.1 - 2.9e-19 68.5 13.5 3.7e-19 68.2 9.3 1.1 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) C1_2 PF03107.11 ETO29058.1 - 0.028 14.5 5.5 0.074 13.1 3.8 1.8 1 1 0 1 1 1 0 C1 domain PH PF00169.24 ETO29059.1 - 1.3e-08 34.9 0.2 2.3e-08 34.1 0.2 1.6 1 1 0 1 1 1 1 PH domain PH_11 PF15413.1 ETO29059.1 - 5.1e-06 26.7 0.1 8.9e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 ETO29059.1 - 0.00037 20.5 0.0 0.00089 19.2 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain HPS3_Mid PF14762.1 ETO29059.1 - 0.075 11.6 0.3 0.094 11.3 0.2 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3, middle region PH_4 PF15404.1 ETO29059.1 - 0.32 10.5 0.1 0.32 10.5 0.1 2.2 1 1 1 2 2 2 0 Pleckstrin homology domain Vfa1 PF08432.5 ETO29059.1 - 0.91 9.5 9.1 1.4 8.9 6.3 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Atrophin-1 PF03154.10 ETO29059.1 - 4 5.4 12.4 6.6 4.7 8.7 1.3 1 1 0 1 1 1 0 Atrophin-1 family PH PF00169.24 ETO29060.1 - 4.4e-25 87.8 12.7 1.1e-11 44.8 0.1 3.5 3 0 0 3 3 3 3 PH domain PH_11 PF15413.1 ETO29060.1 - 1.2e-09 38.4 15.0 0.00014 22.0 1.6 4.7 3 2 0 3 3 3 2 Pleckstrin homology domain PH_3 PF14593.1 ETO29060.1 - 3.4e-05 23.6 7.2 0.13 12.1 0.1 5.1 4 1 1 5 5 5 2 PH domain Mcp5_PH PF12814.2 ETO29060.1 - 4.8e-05 23.2 1.3 0.037 13.9 0.6 3.5 2 1 1 3 3 3 1 Meiotic cell cortex C-terminal pleckstrin homology PH_8 PF15409.1 ETO29060.1 - 8.8e-05 22.5 12.9 0.12 12.5 0.3 4.6 4 2 0 4 4 4 3 Pleckstrin homology domain TRAM_LAG1_CLN8 PF03798.11 ETO29061.1 - 1.1e-26 93.6 23.6 1.9e-26 92.8 16.4 1.3 1 0 0 1 1 1 1 TLC domain CRAL_TRIO PF00650.15 ETO29062.1 - 6.4e-14 51.7 0.8 1.3e-13 50.7 0.2 1.8 2 0 0 2 2 2 1 CRAL/TRIO domain AAA_31 PF13614.1 ETO29062.1 - 0.0077 16.1 0.1 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ubiquitin PF00240.18 ETO29063.1 - 5.2e-12 44.9 0.3 4.8e-11 41.9 0.1 2.3 1 1 1 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 ETO29063.1 - 4.6e-09 35.8 0.2 1.8e-08 33.9 0.1 2.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 ETO29063.1 - 3.4e-06 27.1 1.0 1.1e-05 25.5 0.7 2.0 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain C2 PF00168.25 ETO29063.1 - 7.8e-05 22.4 0.2 0.015 15.1 0.1 2.8 2 0 0 2 2 2 1 C2 domain Strabismus PF06638.6 ETO29063.1 - 0.05 11.9 1.6 0.11 10.8 0.0 2.1 2 0 0 2 2 2 0 Strabismus protein UN_NPL4 PF11543.3 ETO29063.1 - 0.09 13.0 0.7 0.3 11.3 0.0 2.3 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 Beach PF02138.13 ETO29065.1 - 4.7e-31 108.2 0.2 4.7e-31 108.2 0.1 2.6 2 1 1 3 3 3 1 Beige/BEACH domain PH_BEACH PF14844.1 ETO29065.1 - 2.2e-06 27.4 0.9 2.2e-06 27.4 0.6 3.1 3 1 0 3 3 3 1 PH domain associated with Beige/BEACH Beach PF02138.13 ETO29066.1 - 9.2e-60 202.3 0.0 1e-59 202.1 0.0 1.0 1 0 0 1 1 1 1 Beige/BEACH domain Homeobox_KN PF05920.6 ETO29067.1 - 6.6e-13 48.1 1.1 1.2e-12 47.3 0.8 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 ETO29067.1 - 9.9e-09 34.6 0.4 3.5e-08 32.9 0.2 1.9 1 1 1 2 2 2 1 Homeobox domain PE-PPE PF08237.6 ETO29068.1 - 0.013 14.8 0.8 0.024 14.0 0.6 1.4 1 0 0 1 1 1 0 PE-PPE domain BAF1_ABF1 PF04684.8 ETO29068.1 - 0.8 8.4 12.0 0.97 8.2 8.3 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Plasmodium_Vir PF05795.6 ETO29068.1 - 2.5 7.2 7.8 1.1 8.4 3.8 1.5 1 1 1 2 2 2 0 Plasmodium vivax Vir protein DUF4175 PF13779.1 ETO29068.1 - 7 4.2 25.0 9.5 3.7 17.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF3439 PF11921.3 ETO29068.1 - 7.4 6.3 18.7 0.37 10.5 7.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Citrate_synt PF00285.16 ETO29069.1 - 2.6e-49 167.8 0.0 3e-49 167.6 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase Cas_GSU0053 PF09617.5 ETO29069.1 - 0.13 12.0 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) OMP_b-brl PF13505.1 ETO29070.1 - 1.5 8.7 20.9 0.16 11.9 0.3 2.9 3 0 0 3 3 3 0 Outer membrane protein beta-barrel domain RRM_1 PF00076.17 ETO29071.1 - 2.4e-17 62.3 0.6 3e-07 29.9 0.1 3.3 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO29071.1 - 3.3e-11 43.0 0.0 0.00028 20.8 0.0 3.2 3 1 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO29071.1 - 1.7e-05 24.5 0.3 0.0026 17.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.6 ETO29071.1 - 0.028 13.9 0.0 0.064 12.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) RRM_3 PF08777.6 ETO29071.1 - 0.11 12.3 0.1 0.27 11.0 0.1 1.7 1 0 0 1 1 1 0 RNA binding motif Oxidored-like PF09791.4 ETO29073.1 - 1.9e-07 30.4 4.2 4.3e-07 29.2 2.9 1.6 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Neur_chan_memb PF02932.11 ETO29074.1 - 0.0032 17.3 1.0 0.0044 16.9 0.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region ATG22 PF11700.3 ETO29074.1 - 0.0052 15.3 0.3 0.0067 14.9 0.2 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Mem_trans PF03547.13 ETO29074.1 - 0.015 13.6 0.9 0.02 13.1 0.6 1.2 1 0 0 1 1 1 0 Membrane transport protein IncA PF04156.9 ETO29074.1 - 0.019 14.5 2.0 0.03 13.9 1.4 1.3 1 0 0 1 1 1 0 IncA protein DUF1673 PF07895.6 ETO29074.1 - 0.18 11.3 6.5 0.29 10.6 4.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) Kei1 PF08552.6 ETO29074.1 - 0.24 11.0 5.1 0.63 9.6 3.5 1.7 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF1777 PF08648.7 ETO29074.1 - 0.4 10.3 28.4 0.84 9.3 19.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) WD40 PF00400.27 ETO29075.1 - 1.4e-61 202.3 13.3 3.8e-11 42.4 0.2 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO29075.1 - 6.1e-05 21.3 1.9 0.1 10.7 0.0 3.2 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Proteasome_A_N PF10584.4 ETO29075.1 - 0.0055 15.9 1.1 26 4.2 0.0 4.0 4 0 0 4 4 4 3 Proteasome subunit A N-terminal signature PD40 PF07676.7 ETO29075.1 - 2.1 8.0 6.9 3.3 7.4 0.0 4.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat RNA_ligase PF09414.5 ETO29076.1 - 7.5e-05 22.6 0.0 0.24 11.1 0.0 2.2 2 0 0 2 2 2 2 RNA ligase RNA_ligase PF09414.5 ETO29077.1 - 0.0002 21.2 0.0 0.0005 19.9 0.0 1.7 1 0 0 1 1 1 1 RNA ligase WD40 PF00400.27 ETO29078.1 - 9.7e-59 193.2 24.9 1.9e-11 43.3 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO29078.1 - 1.8e-11 42.9 5.7 0.011 13.8 0.0 5.4 2 1 4 6 6 6 5 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO29078.1 - 1.6e-07 31.6 2.2 8.8e-07 29.2 1.5 2.4 1 0 0 1 1 1 1 TRAF-type zinc finger DUF4239 PF14023.1 ETO29078.1 - 0.0018 17.6 1.0 0.0018 17.6 0.7 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4239) Carb_bind PF10645.4 ETO29078.1 - 0.073 12.8 3.8 4.1 7.2 0.2 3.0 2 0 0 2 2 2 0 Carbohydrate binding EF-hand_1 PF00036.27 ETO29079.1 - 4.5e-11 41.2 1.5 2.2e-05 23.4 0.4 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 ETO29079.1 - 2.4e-10 39.8 0.8 0.00022 20.7 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.1 ETO29079.1 - 1.4e-09 37.9 2.6 2.1e-09 37.3 0.4 2.2 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO29079.1 - 3.6e-07 29.4 0.9 0.04 13.8 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 ETO29079.1 - 7.6e-06 25.0 1.1 0.028 13.7 0.0 2.6 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.4 ETO29079.1 - 8.5e-05 22.5 0.7 0.00014 21.8 0.2 1.6 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 ETO29079.1 - 0.0012 18.7 0.1 1.8 8.5 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 ETO29079.1 - 0.012 15.3 0.3 0.34 10.6 0.0 2.2 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand CD36 PF01130.16 ETO29081.1 - 0.018 13.3 4.3 0.022 13.0 3.0 1.1 1 0 0 1 1 1 0 CD36 family GP41 PF00517.12 ETO29081.1 - 0.032 13.7 0.9 0.044 13.3 0.6 1.2 1 0 0 1 1 1 0 Retroviral envelope protein DUF2628 PF10947.3 ETO29081.1 - 0.041 13.6 1.1 0.055 13.2 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) DUF4320 PF14208.1 ETO29081.1 - 0.099 12.5 3.8 4.1 7.3 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4320) DUF3774 PF12609.3 ETO29082.1 - 0.045 14.6 0.1 0.1 13.4 0.1 1.5 1 0 0 1 1 1 0 Wound-induced protein OKR_DC_1_N PF03709.10 ETO29082.1 - 0.062 13.3 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain DUF2222 PF09984.4 ETO29082.1 - 0.13 11.6 2.4 0.25 10.7 1.7 1.4 1 0 0 1 1 1 0 Uncharacterized signal transduction histidine kinase domain (DUF2222) LPP PF04728.8 ETO29084.1 - 0.00013 21.6 2.1 0.011 15.5 0.7 3.0 2 1 1 3 3 3 1 Lipoprotein leucine-zipper Ax_dynein_light PF10211.4 ETO29084.1 - 0.002 17.9 3.3 0.0037 17.1 2.2 1.7 1 1 0 1 1 1 1 Axonemal dynein light chain LOH1CR12 PF10158.4 ETO29084.1 - 0.0026 17.5 0.5 0.0026 17.5 0.4 1.7 2 0 0 2 2 2 1 Tumour suppressor protein Vps5 PF09325.5 ETO29084.1 - 0.0042 16.3 6.4 0.0072 15.6 4.5 1.3 1 0 0 1 1 1 1 Vps5 C terminal like Laminin_II PF06009.7 ETO29084.1 - 0.024 14.3 3.8 0.045 13.5 2.6 1.5 1 0 0 1 1 1 0 Laminin Domain II TAFII28 PF04719.9 ETO29084.1 - 0.026 14.3 2.0 0.026 14.3 0.2 1.9 2 0 0 2 2 2 0 hTAFII28-like protein conserved region Reo_sigmaC PF04582.7 ETO29084.1 - 0.054 12.6 2.2 0.086 12.0 1.5 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF4208 PF13907.1 ETO29084.1 - 0.083 13.1 4.9 0.22 11.7 3.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) Synaptonemal_3 PF15191.1 ETO29084.1 - 0.19 11.5 6.4 0.073 12.8 1.6 2.2 2 1 0 2 2 2 0 Synaptonemal complex central element protein 3 DELLA PF12041.3 ETO29084.1 - 0.21 11.2 2.4 0.63 9.7 0.3 2.8 3 1 1 4 4 4 0 Transcriptional regulator DELLA protein N terminal DUF948 PF06103.6 ETO29084.1 - 0.8 9.6 10.4 0.09 12.6 1.7 2.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Tup_N PF08581.5 ETO29084.1 - 4.6 7.5 9.4 0.4 10.9 0.7 2.8 2 1 1 3 3 3 0 Tup N-terminal Fib_alpha PF08702.5 ETO29084.1 - 6.1 6.9 10.0 2.8 8.0 3.6 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DASH_Dam1 PF08653.5 ETO29084.1 - 6.9 6.5 6.8 2.5e+02 1.5 4.7 2.8 1 1 0 1 1 1 0 DASH complex subunit Dam1 PBP1_TM PF14812.1 ETO29086.1 - 0.057 13.7 6.7 0.074 13.3 4.6 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sporozoite_P67 PF05642.6 ETO29086.1 - 0.1 10.4 1.9 0.096 10.5 1.3 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen YqfQ PF14181.1 ETO29086.1 - 0.12 12.3 6.2 0.12 12.3 4.3 1.1 1 0 0 1 1 1 0 YqfQ-like protein RAP1 PF07218.6 ETO29086.1 - 0.23 9.4 9.0 0.23 9.5 6.3 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Nucleoplasmin PF03066.10 ETO29086.1 - 0.25 10.8 7.1 0.31 10.5 4.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF4530 PF15039.1 ETO29086.1 - 0.3 11.0 7.3 0.41 10.5 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) FAM176 PF14851.1 ETO29086.1 - 0.32 10.6 3.9 0.36 10.5 2.7 1.1 1 0 0 1 1 1 0 FAM176 family RNA_polI_A34 PF08208.6 ETO29086.1 - 0.41 10.2 14.0 0.43 10.2 9.7 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF755 PF05501.6 ETO29086.1 - 0.5 10.4 6.8 0.65 10.0 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) CDC45 PF02724.9 ETO29086.1 - 0.75 7.7 4.6 0.73 7.7 3.2 1.0 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.12 ETO29086.1 - 0.79 9.4 3.2 0.86 9.3 2.3 1.1 1 0 0 1 1 1 0 DDHD domain HNOBA PF07701.9 ETO29086.1 - 1.2 8.3 5.8 1.4 8.1 4.0 1.1 1 0 0 1 1 1 0 Heme NO binding associated RNase_H2-Ydr279 PF09468.5 ETO29086.1 - 1.3 8.1 10.9 1.6 7.8 7.6 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Tom37_C PF11801.3 ETO29086.1 - 3.4 7.4 6.1 3.6 7.4 4.2 1.1 1 0 0 1 1 1 0 Tom37 C-terminal domain Sec62 PF03839.11 ETO29086.1 - 7.2 5.9 9.4 7 5.9 6.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 WD40 PF00400.27 ETO29088.1 - 3.7e-08 32.9 3.0 3.7e-08 32.9 0.5 2.0 2 0 0 2 2 2 1 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO29088.1 - 0.0072 15.1 0.1 0.0088 14.8 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like TPR_12 PF13424.1 ETO29089.1 - 8.8e-34 115.2 0.0 7.5e-17 61.0 0.0 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO29089.1 - 1.4e-17 63.0 2.6 2.4e-11 43.1 0.1 3.3 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 ETO29089.1 - 8.3e-12 44.0 6.1 0.0024 17.6 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO29089.1 - 2.2e-11 42.8 11.1 7.9e-05 22.0 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO29089.1 - 5.3e-11 41.4 0.0 0.025 14.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO29089.1 - 5.8e-10 38.2 6.5 0.012 15.3 0.0 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO29089.1 - 1.1e-09 37.8 0.0 0.0002 21.1 0.0 3.9 5 0 0 5 5 4 2 Tetratricopeptide repeat SNAP PF14938.1 ETO29089.1 - 6.7e-05 22.1 0.0 0.00012 21.3 0.0 1.3 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP MIT PF04212.13 ETO29089.1 - 0.00057 19.7 1.3 0.083 12.7 0.2 3.0 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 ETO29089.1 - 0.0006 20.1 0.1 1 9.9 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO29089.1 - 0.0092 16.1 0.5 2.4 8.5 0.1 3.8 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO29089.1 - 0.08 13.6 0.0 8.1 7.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.27 ETO29091.1 - 2.1e-104 338.0 28.2 8.3e-12 44.5 0.0 11.8 12 0 0 12 12 12 10 WD domain, G-beta repeat NACHT PF05729.7 ETO29091.1 - 9.5e-11 41.6 0.0 2e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Pentapeptide PF00805.17 ETO29091.1 - 1.3e-06 27.4 0.6 2.5e-06 26.5 0.4 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) PD40 PF07676.7 ETO29091.1 - 2e-05 24.1 6.2 23 4.8 0.0 7.3 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Pentapeptide_4 PF13599.1 ETO29091.1 - 6.1e-05 22.7 0.6 0.0002 21.1 0.4 1.9 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA_18 PF13238.1 ETO29091.1 - 0.00056 20.2 0.0 0.00056 20.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 ETO29091.1 - 0.00065 19.8 0.0 0.0026 17.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain Pentapeptide_3 PF13576.1 ETO29091.1 - 0.0016 18.3 0.3 0.0046 16.8 0.2 1.9 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA_17 PF13207.1 ETO29091.1 - 0.0022 18.8 0.0 0.01 16.6 0.0 2.2 1 0 0 1 1 1 1 AAA domain Mid2 PF04478.7 ETO29091.1 - 0.0051 16.2 7.8 0.96 8.8 0.1 4.8 4 2 1 5 5 5 2 Mid2 like cell wall stress sensor UPF0079 PF02367.12 ETO29091.1 - 0.025 14.2 0.0 0.087 12.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 ETO29091.1 - 0.044 13.9 0.0 0.15 12.2 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 ETO29091.1 - 0.12 12.2 0.0 0.38 10.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETO29091.1 - 0.23 11.4 0.3 2.4 8.0 0.0 2.6 2 1 1 3 3 3 0 AAA ATPase domain WD40 PF00400.27 ETO29092.1 - 2.9e-47 156.9 1.0 9.2e-13 47.5 0.0 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO29092.1 - 7.5e-09 34.2 3.3 0.22 9.5 0.0 4.0 1 1 3 4 4 4 4 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO29092.1 - 5.6e-06 26.1 0.0 1.1 9.3 0.0 4.0 3 1 1 4 4 4 1 Domain of unknown function (DUF3601) PD40 PF07676.7 ETO29092.1 - 0.0023 17.5 1.6 13 5.5 0.0 3.7 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO29092.1 - 0.0045 16.4 0.6 0.017 14.5 0.4 1.8 1 1 0 1 1 1 1 PQQ-like domain Nbas_N PF15492.1 ETO29092.1 - 0.019 14.1 0.7 3.1 6.8 0.0 2.9 1 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Mid2 PF04478.7 ETO29092.1 - 0.043 13.2 2.5 6.6 6.1 0.0 3.2 2 1 2 4 4 4 0 Mid2 like cell wall stress sensor NYD-SP28_assoc PF14775.1 ETO29092.1 - 0.055 13.1 0.7 20 5.0 0.0 3.6 4 0 0 4 4 4 0 Sperm tail C-terminal domain cobW PF02492.14 ETO29093.1 - 1e-13 51.1 0.1 1e-13 51.1 0.1 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 ETO29093.1 - 0.00082 19.1 0.2 0.0023 17.6 0.1 1.9 2 1 0 2 2 2 1 Archaeal ATPase MobB PF03205.9 ETO29093.1 - 0.0024 17.5 0.2 0.0049 16.5 0.1 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 ETO29093.1 - 0.021 14.4 0.1 0.053 13.1 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 ETO29093.1 - 0.035 14.2 0.7 0.066 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 ETO29093.1 - 0.048 13.1 0.2 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_33 PF13671.1 ETO29093.1 - 0.055 13.3 0.1 0.055 13.3 0.0 2.8 4 0 0 4 4 4 0 AAA domain AAA_14 PF13173.1 ETO29093.1 - 0.079 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 ETO29093.1 - 0.12 11.8 0.1 0.12 11.8 0.0 2.7 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.1 ETO29093.1 - 0.32 11.2 4.1 0.51 10.6 0.1 2.7 3 0 0 3 3 3 0 AAA domain DUF4512 PF14975.1 ETO29093.1 - 3.6 8.4 8.1 89 4.0 0.0 2.7 2 2 0 2 2 2 0 Domain of unknown function (DUF4512) Spore_coat_CotO PF14153.1 ETO29094.1 - 0.0004 19.8 5.5 0.0004 19.8 3.8 3.1 3 0 0 3 3 3 1 Spore coat protein CotO eIF-3_zeta PF05091.7 ETO29094.1 - 0.0032 16.1 6.7 0.0032 16.1 4.6 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3395 PF11875.3 ETO29094.1 - 0.0035 16.9 3.2 0.0035 16.9 2.2 3.9 3 1 1 4 4 4 1 Domain of unknown function (DUF3395) Pex14_N PF04695.8 ETO29094.1 - 0.0097 15.9 13.5 0.0097 15.9 9.4 2.7 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Auxin_canalis PF05703.6 ETO29094.1 - 0.022 14.5 0.7 0.022 14.5 0.5 2.4 2 1 0 2 2 2 0 Auxin canalisation RNA_pol_Rpb1_5 PF04998.12 ETO29094.1 - 0.27 10.4 5.9 0.28 10.4 0.5 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 5 AIF_C PF14721.1 ETO29094.1 - 0.27 11.4 15.9 0.049 13.8 5.4 3.1 3 0 0 3 3 3 0 Apoptosis-inducing factor, mitochondrion-associated, C-term UPF0564 PF10595.4 ETO29094.1 - 1.6 7.5 43.0 3.9 6.2 29.8 1.6 1 1 0 1 1 1 0 Uncharacterised protein family UPF0564 DUF106 PF01956.11 ETO29094.1 - 3 7.3 22.3 0.041 13.4 2.7 2.8 3 0 0 3 3 3 0 Integral membrane protein DUF106 FAM222A PF15258.1 ETO29094.1 - 3.9 6.5 22.1 8.3 5.5 15.3 1.4 1 0 0 1 1 1 0 Protein family of FAM222A Peptidase_S49_N PF08496.5 ETO29094.1 - 4.3 7.1 24.0 0.62 9.8 5.2 3.6 3 0 0 3 3 3 0 Peptidase family S49 N-terminal RR_TM4-6 PF06459.7 ETO29094.1 - 4.4 7.1 21.0 0.51 10.1 5.5 3.1 3 0 0 3 3 3 0 Ryanodine Receptor TM 4-6 Kei1 PF08552.6 ETO29094.1 - 5 6.7 9.1 0.19 11.4 1.5 2.1 3 0 0 3 3 3 0 Inositolphosphorylceramide synthase subunit Kei1 DDHD PF02862.12 ETO29094.1 - 9.3 5.9 25.6 0.44 10.2 7.4 2.7 3 1 0 3 3 3 0 DDHD domain Kelch_6 PF13964.1 ETO29095.1 - 5.2e-05 23.2 0.0 0.0012 18.8 0.0 3.0 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 ETO29095.1 - 0.00036 20.6 0.0 0.0014 18.7 0.0 2.0 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO29095.1 - 0.011 15.4 0.0 0.039 13.7 0.0 1.9 1 0 0 1 1 1 0 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO29095.1 - 0.015 14.8 0.2 0.049 13.1 0.1 1.9 1 0 0 1 1 1 0 Kelch motif Kelch_2 PF07646.10 ETO29095.1 - 0.067 12.9 0.1 0.35 10.6 0.0 2.2 2 0 0 2 2 2 0 Kelch motif SAM_2 PF07647.12 ETO29097.1 - 2.9e-10 39.8 0.6 5.1e-10 39.0 0.4 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO29097.1 - 1.2e-09 38.2 0.4 2.2e-09 37.3 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF1515 PF07439.6 ETO29097.1 - 0.015 15.0 0.7 0.015 15.0 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) HSBP1 PF06825.7 ETO29097.1 - 0.015 14.8 2.2 0.21 11.1 0.0 2.9 2 1 1 3 3 3 0 Heat shock factor binding protein 1 SAM_PNT PF02198.11 ETO29097.1 - 0.037 13.7 0.0 0.083 12.6 0.0 1.7 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain MotCF PF09158.5 ETO29097.1 - 0.089 12.4 0.7 0.22 11.2 0.5 1.6 1 0 0 1 1 1 0 Bacteriophage T4 MotA, C-terminal DUF3373 PF11853.3 ETO29097.1 - 0.53 8.7 11.4 0.058 11.9 4.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) Allexi_40kDa PF05549.6 ETO29097.1 - 4.5 6.5 13.0 4.5 6.4 0.6 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein PfkB PF00294.19 ETO29099.1 - 1.8e-11 43.7 0.4 3.2e-11 42.9 0.3 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase SIS PF01380.17 ETO29099.1 - 0.026 14.1 0.3 0.13 11.9 0.1 2.2 3 0 0 3 3 3 0 SIS domain SIS_2 PF13580.1 ETO29099.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 SIS domain Pkinase PF00069.20 ETO29101.1 - 5.9e-13 48.5 0.0 9.8e-10 38.0 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO29101.1 - 0.0078 15.3 0.0 0.034 13.1 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase UQ_con PF00179.21 ETO29102.1 - 3.2e-48 162.7 0.0 4.2e-48 162.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 ETO29102.1 - 2.3e-07 30.6 0.0 3.1e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UBA PF00627.26 ETO29102.1 - 0.0012 18.6 0.1 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain UEV PF05743.8 ETO29102.1 - 0.017 14.8 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 UEV domain RGS-like PF09128.6 ETO29102.1 - 0.018 14.5 1.4 1.4 8.3 0.1 2.1 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain S-methyl_trans PF02574.11 ETO29102.1 - 0.036 13.3 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Homocysteine S-methyltransferase RWD PF05773.17 ETO29102.1 - 0.046 13.6 0.1 0.062 13.2 0.0 1.5 1 1 0 1 1 1 0 RWD domain TcdB_N PF12918.2 ETO29103.1 - 0.051 13.6 0.9 0.14 12.2 0.6 1.8 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain DUF4062 PF13271.1 ETO29104.1 - 0.0041 17.0 0.0 0.079 12.9 0.0 2.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4062) MNNL PF07657.8 ETO29104.1 - 0.018 14.9 3.8 0.052 13.4 0.0 2.9 3 0 0 3 3 3 0 N terminus of Notch ligand DUF1307 PF06998.6 ETO29104.1 - 0.084 12.9 2.3 0.18 11.8 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1307) TPR_12 PF13424.1 ETO29105.1 - 3.4e-28 97.4 3.4 8.6e-16 57.6 0.1 5.3 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETO29105.1 - 4.6e-11 42.1 6.1 7e-06 25.6 0.1 4.8 3 2 1 4 4 4 3 TPR repeat TPR_10 PF13374.1 ETO29105.1 - 4.9e-11 42.1 1.0 4.5e-05 23.2 0.0 5.4 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO29105.1 - 2.1e-09 36.4 0.9 0.0038 16.9 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat NACHT PF05729.7 ETO29105.1 - 6.3e-08 32.4 0.6 1e-06 28.4 0.4 2.6 1 1 0 1 1 1 1 NACHT domain TPR_2 PF07719.12 ETO29105.1 - 6.1e-07 28.8 6.9 0.95 9.5 0.0 5.4 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO29105.1 - 6.8e-07 28.6 12.3 0.4 10.3 0.0 5.9 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO29105.1 - 5.2e-05 22.7 3.7 4.2 7.3 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_22 PF13401.1 ETO29105.1 - 7.5e-05 22.8 0.2 0.00066 19.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 ETO29105.1 - 0.00095 19.2 0.0 0.05 13.6 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.1 ETO29105.1 - 0.0013 18.7 0.0 0.0095 15.9 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain TPR_6 PF13174.1 ETO29105.1 - 0.016 15.6 2.3 6.2 7.5 0.0 5.1 6 1 0 6 6 5 0 Tetratricopeptide repeat Arch_ATPase PF01637.13 ETO29105.1 - 0.028 14.1 0.9 0.06 13.0 0.1 2.1 2 1 0 2 2 2 0 Archaeal ATPase NTPase_1 PF03266.10 ETO29105.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 NTPase WD40 PF00400.27 ETO29106.1 - 1.3e-156 503.6 49.6 1.5e-12 46.8 0.3 15.6 15 0 0 15 15 15 14 WD domain, G-beta repeat NACHT PF05729.7 ETO29106.1 - 2.2e-07 30.6 0.0 5.2e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain DUF1258 PF06869.7 ETO29106.1 - 2.3e-07 30.1 8.6 1.3 7.9 0.0 7.6 4 1 7 11 11 11 3 Protein of unknown function (DUF1258) AAA_22 PF13401.1 ETO29106.1 - 1.8e-05 24.9 0.0 5.5e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain Pentapeptide_4 PF13599.1 ETO29106.1 - 2.4e-05 24.0 0.8 7.6e-05 22.4 0.6 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETO29106.1 - 9.7e-05 21.5 1.9 0.00026 20.1 1.3 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) AAA_18 PF13238.1 ETO29106.1 - 0.0011 19.3 1.9 0.0044 17.3 0.0 3.2 2 1 1 3 3 3 1 AAA domain Pentapeptide_3 PF13576.1 ETO29106.1 - 0.0012 18.6 0.5 0.0042 16.9 0.3 2.0 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Gmad1 PF10647.4 ETO29106.1 - 0.002 17.5 0.1 3.5 6.9 0.0 4.2 2 1 0 3 3 3 1 Lipoprotein LpqB beta-propeller domain AAA_17 PF13207.1 ETO29106.1 - 0.003 18.3 0.0 0.015 16.0 0.0 2.3 1 0 0 1 1 1 1 AAA domain PD40 PF07676.7 ETO29106.1 - 0.0069 16.0 18.6 14 5.5 0.0 8.5 9 0 0 9 9 9 0 WD40-like Beta Propeller Repeat NYD-SP28_assoc PF14775.1 ETO29106.1 - 0.041 13.5 14.2 4 7.1 0.1 9.4 13 0 0 13 13 12 0 Sperm tail C-terminal domain DUF3385 PF11865.3 ETO29107.1 - 0.4 10.5 5.2 0.86 9.5 0.2 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF3385) Mg_trans_NIPA PF05653.9 ETO29108.1 - 0.011 14.7 0.4 0.012 14.5 0.3 1.1 1 0 0 1 1 1 0 Magnesium transporter NIPA DUF4061 PF13270.1 ETO29108.1 - 0.036 14.1 2.0 0.056 13.5 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) MSC PF09402.5 ETO29108.1 - 0.051 12.2 1.9 0.058 12.1 1.3 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain DUF1385 PF07136.6 ETO29108.1 - 0.12 11.4 0.8 0.14 11.1 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) Sec23_BS PF08033.7 ETO29109.1 - 6.4e-22 77.8 1.3 1.2e-21 77.0 0.9 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_trunk PF04811.10 ETO29109.1 - 1.2e-19 70.6 0.1 7.5e-18 64.7 0.0 2.9 2 1 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 ETO29109.1 - 1.1e-18 66.5 0.3 2.5e-18 65.3 0.2 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain GSH_synth_ATP PF03917.12 ETO29110.1 - 2.7e-51 174.3 0.5 6.6e-27 94.0 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 ETO29110.1 - 2.3e-28 98.3 0.1 1.5e-25 89.2 0.0 3.1 1 1 0 1 1 1 1 Eukaryotic glutathione synthase Glyco_hydro_16 PF00722.16 ETO29111.1 - 5.7e-12 45.2 2.1 9e-12 44.6 1.4 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 m04gp34like PF12216.3 ETO29111.1 - 0.17 11.2 0.4 0.24 10.7 0.3 1.1 1 0 0 1 1 1 0 Immune evasion protein Bacillus_HBL PF05791.6 ETO29112.1 - 0.018 14.4 0.6 0.018 14.4 0.4 1.8 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Surface_Ag_2 PF01617.12 ETO29112.1 - 0.05 12.7 0.1 0.087 12.0 0.0 1.4 1 0 0 1 1 1 0 Surface antigen Pkinase PF00069.20 ETO29114.1 - 2.5e-38 131.7 0.4 2.8e-38 131.5 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO29114.1 - 2.6e-21 75.8 0.1 3.1e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO29114.1 - 6.8e-07 28.5 1.3 1e-06 27.9 0.9 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 ETO29114.1 - 4.2e-06 26.2 1.3 5.4e-06 25.8 0.9 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 ETO29114.1 - 2.2e-05 24.3 0.3 0.0085 15.8 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 ETO29114.1 - 0.0024 17.2 1.5 0.0035 16.7 0.1 1.9 2 1 1 3 3 3 1 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 ETO29114.1 - 0.01 15.4 2.5 0.027 14.0 1.7 1.8 1 1 0 1 1 1 0 Choline/ethanolamine kinase ATPgrasp_Ter PF15632.1 ETO29114.1 - 0.034 12.9 0.1 0.061 12.0 0.1 1.4 1 1 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Imm5 PF14423.1 ETO29114.1 - 0.047 13.3 0.1 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 Immunity protein Imm5 Rot1 PF10681.4 ETO29114.1 - 0.11 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal adh_short PF00106.20 ETO29115.1 - 2.5e-15 56.7 0.1 6e-15 55.5 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase DUF1776 PF08643.5 ETO29115.1 - 1.5e-07 30.8 0.0 2.4e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Mucin PF01456.12 ETO29115.1 - 0.00016 21.4 10.0 0.00024 20.9 6.9 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein KR PF08659.5 ETO29115.1 - 0.0028 17.3 0.0 0.0048 16.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Dicty_REP PF05086.7 ETO29115.1 - 0.0067 14.2 0.5 0.0078 14.0 0.3 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Colipase-like PF15083.1 ETO29115.1 - 0.009 15.9 0.2 0.024 14.5 0.1 1.7 1 0 0 1 1 1 1 Colipase-like Interfer-bind PF09294.5 ETO29115.1 - 0.018 15.0 1.3 0.039 13.9 0.9 1.6 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III adh_short_C2 PF13561.1 ETO29115.1 - 0.02 14.6 0.2 0.037 13.8 0.2 1.4 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase SR-25 PF10500.4 ETO29116.1 - 2.4e-05 23.9 26.6 3e-05 23.6 18.5 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Daxx PF03344.10 ETO29116.1 - 0.35 9.2 25.3 0.41 9.0 17.5 1.0 1 0 0 1 1 1 0 Daxx Family Cwf_Cwc_15 PF04889.7 ETO29116.1 - 0.59 9.8 25.9 0.71 9.5 18.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MIP-T3 PF10243.4 ETO29116.1 - 2 6.7 32.6 2.3 6.5 22.6 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Macoilin PF09726.4 ETO29116.1 - 2.3 6.3 17.4 2.7 6.1 12.0 1.0 1 0 0 1 1 1 0 Transmembrane protein BUD22 PF09073.5 ETO29116.1 - 2.5 7.0 29.6 3 6.7 20.5 1.1 1 0 0 1 1 1 0 BUD22 XRCC4 PF06632.7 ETO29116.1 - 2.9 6.6 20.7 14 4.3 14.3 1.8 1 1 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 CDC45 PF02724.9 ETO29116.1 - 3.2 5.6 21.6 4 5.3 14.9 1.0 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 ETO29116.1 - 4.6 6.4 15.3 5.5 6.1 10.6 1.1 1 0 0 1 1 1 0 NOA36 protein Trypan_PARP PF05887.6 ETO29116.1 - 5.1 6.8 12.7 6.7 6.5 8.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3827 PF12877.2 ETO29116.1 - 6 4.8 15.8 6.9 4.6 10.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) SAPS PF04499.10 ETO29116.1 - 6.3 5.3 18.9 7.3 5.1 13.1 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.7 ETO29116.1 - 6.5 4.5 27.0 7.6 4.3 18.7 1.0 1 0 0 1 1 1 0 Nop14-like family Neur_chan_memb PF02932.11 ETO29116.1 - 7.5 6.3 10.3 9.9 5.9 7.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4551 PF15087.1 ETO29116.1 - 7.7 4.7 14.0 8.7 4.5 9.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Pilt PF15453.1 ETO29116.1 - 9.7 5.7 17.4 12 5.5 12.1 1.0 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions DUF2201_N PF13203.1 ETO29118.1 - 0.21 10.7 3.6 0.21 10.7 2.5 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain Dala_Dala_lig_N PF01820.16 ETO29118.1 - 0.26 11.6 3.3 0.32 11.3 2.3 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus RR_TM4-6 PF06459.7 ETO29118.1 - 1.5 8.6 9.8 1.7 8.4 6.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3381 PF11861.3 ETO29118.1 - 1.8 8.0 17.2 2.5 7.5 11.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF2058 PF09831.4 ETO29118.1 - 1.9 8.3 15.5 2.2 8.1 10.7 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DDHD PF02862.12 ETO29118.1 - 3.4 7.4 7.8 3.7 7.2 5.4 1.1 1 0 0 1 1 1 0 DDHD domain DUF936 PF06075.7 ETO29118.1 - 5 5.9 11.1 5.7 5.7 7.7 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) MIP-T3 PF10243.4 ETO29118.1 - 6.4 5.1 20.9 7 4.9 14.5 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 G-alpha PF00503.15 ETO29119.1 - 7.7e-23 80.7 9.2 4e-22 78.4 6.4 1.9 1 1 0 1 1 1 1 G-protein alpha subunit AAA_29 PF13555.1 ETO29119.1 - 0.062 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 ETO29119.1 - 0.064 12.1 0.5 6.4 5.5 0.0 2.8 1 1 2 3 3 3 0 Type II/IV secretion system protein Aldedh PF00171.17 ETO29120.1 - 0.023 13.0 0.0 0.031 12.6 0.0 1.1 1 0 0 1 1 1 0 Aldehyde dehydrogenase family GlcNAc PF11397.3 ETO29121.1 - 7.7e-64 215.9 2.1 2.3e-60 204.5 1.5 3.1 1 1 0 1 1 1 1 Glycosyltransferase (GlcNAc) Mem_trans PF03547.13 ETO29122.1 - 0.0068 14.7 0.2 0.0096 14.2 0.1 1.1 1 0 0 1 1 1 1 Membrane transport protein RGS PF00615.14 ETO29122.1 - 0.0075 16.3 0.7 0.0075 16.3 0.5 2.2 2 1 0 2 2 2 1 Regulator of G protein signaling domain GWT1 PF06423.7 ETO29122.1 - 0.0097 16.0 2.1 0.023 14.7 1.5 1.7 1 0 0 1 1 1 1 GWT1 Alpha-mann_mid PF09261.6 ETO29122.1 - 0.076 13.2 0.5 0.18 12.0 0.3 1.6 1 0 0 1 1 1 0 Alpha mannosidase, middle domain D123 PF07065.9 ETO29123.1 - 5.3e-12 45.4 4.7 1.6e-07 30.6 0.1 3.6 3 1 0 3 3 3 3 D123 RGS PF00615.14 ETO29124.1 - 9e-06 25.7 0.5 1.9e-05 24.7 0.3 1.5 1 1 0 1 1 1 1 Regulator of G protein signaling domain DUF4144 PF13642.1 ETO29124.1 - 0.023 15.0 0.1 0.041 14.2 0.0 1.4 1 0 0 1 1 1 0 protein structure with unknown function EF-hand_5 PF13202.1 ETO29125.1 - 6.3e-14 50.5 7.8 7.3e-07 28.2 0.5 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 ETO29125.1 - 1.5e-12 47.4 2.2 1.5e-12 47.4 1.5 2.3 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO29125.1 - 2.4e-12 45.1 10.6 1.1e-06 27.4 0.3 2.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 ETO29125.1 - 3.5e-10 38.8 5.2 8.4e-05 22.1 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 ETO29125.1 - 2e-09 36.8 1.3 0.00028 20.4 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 ETO29125.1 - 0.0012 18.8 5.8 0.0055 16.7 4.0 2.2 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.13 ETO29125.1 - 0.0072 15.9 0.8 0.0072 15.9 0.6 2.3 2 0 0 2 2 2 1 Dockerin type I repeat Gasdermin PF04598.7 ETO29125.1 - 0.011 14.5 1.5 0.011 14.5 1.1 1.2 1 0 0 1 1 1 0 Gasdermin family VCBS PF13517.1 ETO29125.1 - 0.068 13.5 1.3 1.1 9.6 0.1 2.7 2 1 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella RNA_pol_Rpb5_N PF03871.9 ETO29125.1 - 0.19 12.1 1.7 1.4 9.3 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb5, N-terminal domain EF-hand_4 PF12763.2 ETO29125.1 - 0.45 10.2 3.0 19 5.0 0.1 2.8 1 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand adh_short_C2 PF13561.1 ETO29126.1 - 2.4e-10 40.6 0.0 6.4e-10 39.2 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETO29126.1 - 1.2e-09 38.2 0.0 3.6e-09 36.7 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Sugar_tr PF00083.19 ETO29127.1 - 1.2e-06 27.3 1.0 1.2e-06 27.3 0.7 2.1 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 ETO29127.1 - 4.1e-05 22.4 8.7 0.00026 19.8 6.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily PsaL PF02605.10 ETO29127.1 - 0.057 12.9 0.4 0.1 12.0 0.0 1.5 2 0 0 2 2 2 0 Photosystem I reaction centre subunit XI Disintegrin PF00200.18 ETO29129.1 - 4.3e-15 55.6 29.8 4.3e-15 55.6 20.7 8.3 6 1 2 8 8 8 1 Disintegrin WW PF00397.21 ETO29129.1 - 4.7e-08 32.7 2.9 1.3e-07 31.3 2.0 1.8 1 0 0 1 1 1 1 WW domain Reprolysin_2 PF13574.1 ETO29129.1 - 6.2e-08 32.8 1.5 2.7e-07 30.8 1.0 2.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 ETO29129.1 - 1.5e-06 27.8 2.0 1.5e-06 27.8 1.4 2.2 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like DUF106 PF01956.11 ETO29129.1 - 0.093 12.2 0.8 0.25 10.8 0.6 1.7 1 0 0 1 1 1 0 Integral membrane protein DUF106 Reprolysin_3 PF13582.1 ETO29129.1 - 0.11 12.9 2.0 0.23 11.9 0.3 2.6 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like ATP-synt_B PF00430.13 ETO29129.1 - 0.25 11.1 9.5 0.38 10.5 6.6 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) LMBR1 PF04791.11 ETO29129.1 - 1.5 7.3 3.2 2.3 6.7 2.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Peptidase_S49_N PF08496.5 ETO29129.1 - 4.6 7.0 9.2 1.5 8.6 4.2 1.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Transgly PF00912.17 ETO29130.1 - 0.06 12.6 0.1 0.089 12.0 0.0 1.3 1 0 0 1 1 1 0 Transglycosylase MRG PF05712.8 ETO29131.1 - 8.4e-28 96.5 9.6 4.9e-21 74.5 2.4 2.5 2 0 0 2 2 2 2 MRG WD40 PF00400.27 ETO29132.1 - 3.3e-172 553.0 45.0 1.6e-13 49.9 0.1 16.4 16 0 0 16 16 16 16 WD domain, G-beta repeat Nup160 PF11715.3 ETO29132.1 - 7.6e-14 50.7 28.1 0.083 11.0 0.1 12.6 1 1 11 12 12 12 6 Nucleoporin Nup120/160 NACHT PF05729.7 ETO29132.1 - 2.6e-11 43.4 0.0 7.4e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 NACHT domain Pentapeptide PF00805.17 ETO29132.1 - 1e-05 24.6 2.5 2.2e-05 23.5 1.7 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO29132.1 - 3.5e-05 23.5 0.2 0.00014 21.6 0.1 2.0 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA_18 PF13238.1 ETO29132.1 - 0.0002 21.6 0.2 0.0002 21.6 0.1 4.4 4 1 1 5 5 4 1 AAA domain AAA_22 PF13401.1 ETO29132.1 - 0.00022 21.3 0.0 0.00081 19.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain DUF1652 PF07865.6 ETO29132.1 - 0.00024 20.6 0.1 1.6 8.3 0.0 6.1 6 0 0 6 6 6 1 Protein of unknown function (DUF1652) AAA_17 PF13207.1 ETO29132.1 - 0.00078 20.2 0.0 0.007 17.1 0.0 2.8 1 0 0 1 1 1 1 AAA domain Pentapeptide_3 PF13576.1 ETO29132.1 - 0.0027 17.5 0.8 0.009 15.8 0.6 1.9 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) PD40 PF07676.7 ETO29132.1 - 0.0096 15.5 23.1 17 5.2 0.1 8.8 9 0 0 9 9 9 0 WD40-like Beta Propeller Repeat Zn-ribbon_8 PF09723.5 ETO29132.1 - 0.034 14.0 0.6 0.15 12.0 0.0 2.3 2 0 0 2 2 2 0 Zinc ribbon domain AAA_5 PF07728.9 ETO29132.1 - 0.049 13.3 0.1 1.7 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PLD_C PF12357.3 ETO29132.1 - 0.075 12.5 0.0 61 3.2 0.0 5.0 4 0 0 4 4 4 0 Phospholipase D C terminal Resistin PF06954.6 ETO29132.1 - 0.089 13.0 1.0 31 4.9 0.0 5.0 5 1 0 6 6 5 0 Resistin AAA_16 PF13191.1 ETO29132.1 - 0.099 12.6 0.0 0.41 10.5 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain ApoL PF05461.6 ETO29133.1 - 0.0099 15.1 0.3 0.062 12.5 0.1 1.9 2 0 0 2 2 2 1 Apolipoprotein L Tropomyosin_1 PF12718.2 ETO29138.1 - 0.0055 16.5 3.4 0.0055 16.5 2.3 4.5 4 0 0 4 4 4 2 Tropomyosin like V-SNARE PF05008.10 ETO29138.1 - 0.016 15.3 4.6 0.016 15.3 3.2 4.7 5 0 0 5 5 4 0 Vesicle transport v-SNARE protein N-terminus CLN3 PF02487.12 ETO29138.1 - 0.023 13.4 0.3 0.023 13.4 0.2 2.4 3 0 0 3 3 3 0 CLN3 protein DUF2672 PF10878.3 ETO29138.1 - 0.048 13.4 0.4 0.048 13.4 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2672) Sas10_Utp3 PF04000.10 ETO29138.1 - 0.14 12.3 0.2 0.14 12.3 0.1 4.3 4 1 0 4 4 4 0 Sas10/Utp3/C1D family Mlf1IP PF10248.4 ETO29138.1 - 0.2 11.2 3.5 7 6.2 0.3 2.9 3 0 0 3 3 3 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Mnd1 PF03962.10 ETO29138.1 - 0.3 10.7 36.1 2.5 7.7 1.3 4.2 4 0 0 4 4 4 0 Mnd1 family DUF4140 PF13600.1 ETO29138.1 - 1.8 9.0 20.0 3.7 8.0 0.0 4.4 4 0 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) Adaptin_binding PF10199.4 ETO29138.1 - 2.5 8.4 20.8 0.055 13.7 3.3 3.0 3 0 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 DUF607 PF04678.8 ETO29138.1 - 6.2 6.7 17.0 3.1 7.6 0.8 4.2 2 1 2 4 4 4 0 Protein of unknown function, DUF607 DUF2316 PF10078.4 ETO29138.1 - 7.5 6.6 9.9 1.2 9.1 0.5 3.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2316) NapE PF06796.6 ETO29138.1 - 8 5.8 6.7 4.1 6.7 0.1 3.5 3 0 0 3 3 3 0 Periplasmic nitrate reductase protein NapE ATG27 PF09451.5 ETO29139.1 - 0.00033 19.9 1.1 0.00046 19.5 0.8 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 7tm_1 PF00001.16 ETO29139.1 - 0.0018 17.4 5.8 0.0041 16.3 4.0 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PgaD PF13994.1 ETO29139.1 - 0.16 11.4 0.7 0.35 10.3 0.5 1.6 1 1 0 1 1 1 0 PgaD-like protein Peroxin-13_N PF04088.8 ETO29139.1 - 0.47 10.3 3.3 1.5 8.7 0.5 2.6 2 1 1 3 3 3 0 Peroxin 13, N-terminal region DUF2628 PF10947.3 ETO29139.1 - 4.5 7.1 8.4 2.3 8.0 3.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2628) RAB3GAP2_N PF14655.1 ETO29140.1 - 0.021 13.8 4.9 0.032 13.2 3.4 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus AAA_23 PF13476.1 ETO29140.1 - 0.033 14.5 13.9 0.057 13.7 9.7 1.3 1 0 0 1 1 1 0 AAA domain DUF3323 PF11796.3 ETO29140.1 - 0.14 11.4 3.5 0.32 10.2 1.9 1.8 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) FHIPEP PF00771.15 ETO29140.1 - 0.42 8.8 8.1 2.7 6.1 0.1 2.1 2 0 0 2 2 2 0 FHIPEP family Conotoxin PF02950.12 ETO29140.1 - 2.8 8.7 5.2 3 8.6 0.8 3.1 3 1 0 3 3 3 0 Conotoxin PRCH PF03967.8 ETO29141.1 - 0.79 9.3 4.8 0.26 10.8 0.9 2.0 3 0 0 3 3 3 0 Photosynthetic reaction centre, H-chain N-terminal region DUF2457 PF10446.4 ETO29142.1 - 0.11 11.1 11.8 0.16 10.6 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Macoilin PF09726.4 ETO29142.1 - 0.4 8.9 11.8 0.49 8.6 8.2 1.0 1 0 0 1 1 1 0 Transmembrane protein Pox_RNA_Pol_19 PF05320.7 ETO29142.1 - 0.54 9.9 5.0 0.78 9.4 3.5 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Menin PF05053.8 ETO29142.1 - 3 5.9 6.9 3.5 5.6 4.8 1.1 1 0 0 1 1 1 0 Menin PBP1_TM PF14812.1 ETO29142.1 - 3.3 8.0 5.9 6.2 7.2 4.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Beach PF02138.13 ETO29143.1 - 3.5e-108 361.1 0.3 4.7e-108 360.7 0.2 1.2 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 ETO29143.1 - 2.2e-09 37.0 0.1 4.1e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 ETO29143.1 - 4.1e-07 29.6 0.2 2.4e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 WD domain, G-beta repeat Adap_comp_sub PF00928.16 ETO29144.1 - 1e-77 260.7 0.6 1.3e-77 260.4 0.4 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Abhydrolase_3 PF07859.8 ETO29146.1 - 9.6e-29 100.4 0.0 1.4e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 ETO29146.1 - 3.5e-17 62.1 0.3 1.6e-16 59.9 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 ETO29146.1 - 2.1e-05 24.3 0.0 2.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETO29146.1 - 0.0018 18.2 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 ETO29146.1 - 0.0045 15.7 0.1 0.19 10.4 0.0 2.3 2 0 0 2 2 2 1 Carboxylesterase family KIAA1328 PF15369.1 ETO29147.1 - 0.49 10.1 31.1 0.84 9.3 21.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 WD40 PF00400.27 ETO29148.1 - 1.7e-43 145.0 12.8 1.4e-10 40.6 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat PD40 PF07676.7 ETO29148.1 - 2.4e-05 23.8 6.5 0.2 11.3 0.1 5.2 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO29148.1 - 0.00071 17.9 0.3 0.27 9.5 0.0 2.9 1 1 2 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.3 ETO29148.1 - 0.0012 17.0 0.6 1.1 7.2 0.0 3.7 2 2 1 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO29148.1 - 0.0029 17.1 0.0 0.64 9.4 0.0 2.7 2 1 0 2 2 2 1 PQQ-like domain Nucleoporin_N PF08801.6 ETO29148.1 - 0.0031 16.3 6.0 1.4 7.6 0.3 4.2 1 1 2 3 3 3 2 Nup133 N terminal like Str_synth PF03088.11 ETO29148.1 - 0.0076 16.2 0.0 0.46 10.5 0.0 3.5 2 1 1 3 3 3 1 Strictosidine synthase Cnd3 PF12719.2 ETO29149.1 - 1.7e-38 132.2 2.7 2.5e-38 131.7 1.9 1.2 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain RMP PF14996.1 ETO29149.1 - 0.0001 22.2 0.3 0.0001 22.2 0.2 2.6 3 0 0 3 3 3 1 Retinal Maintenance DUF3926 PF13080.1 ETO29149.1 - 0.014 14.8 0.3 0.05 13.1 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3926) Xpo1 PF08389.7 ETO29150.1 - 0.0054 16.6 0.6 0.92 9.4 0.0 2.8 3 0 0 3 3 3 2 Exportin 1-like protein VHS PF00790.14 ETO29150.1 - 0.017 14.7 0.3 0.042 13.4 0.2 1.7 1 0 0 1 1 1 0 VHS domain Membr_traf_MHD PF10540.4 ETO29150.1 - 0.071 12.9 0.8 0.19 11.5 0.6 1.7 1 0 0 1 1 1 0 Munc13 (mammalian uncoordinated) homology domain Herpes_ori_bp PF02399.10 ETO29151.1 - 0.0025 15.8 0.5 0.0031 15.5 0.3 1.1 1 0 0 1 1 1 1 Origin of replication binding protein DUF4509 PF14970.1 ETO29151.1 - 0.03 13.9 0.9 0.041 13.5 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) DUF4238 PF14022.1 ETO29151.1 - 0.081 12.1 2.2 0.095 11.9 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) GvpK PF05121.7 ETO29151.1 - 1.3 8.8 4.8 18 5.2 0.2 2.7 1 1 2 3 3 3 0 Gas vesicle protein K DUF2797 PF10977.3 ETO29152.1 - 1.3 8.5 7.9 0.18 11.3 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2797) PEP-utilisers_N PF05524.8 ETO29152.1 - 1.6 8.5 12.6 0.7 9.7 2.7 2.9 1 1 2 3 3 3 0 PEP-utilising enzyme, N-terminal Med30 PF11315.3 ETO29152.1 - 3.5 7.7 18.5 4 7.5 6.3 3.3 1 1 1 2 2 2 0 Mediator complex subunit 30 Apolipoprotein PF01442.13 ETO29152.1 - 9.1 5.7 23.6 5 6.5 8.6 2.8 2 2 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF4094 PF13334.1 ETO29153.1 - 2.7 8.4 6.7 15 6.0 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) WD40 PF00400.27 ETO29155.1 - 2.6e-68 223.6 23.6 7.1e-12 44.7 1.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO29155.1 - 5e-12 44.7 10.1 0.00051 18.3 0.1 5.6 2 1 2 5 5 5 5 Nucleoporin Nup120/160 ABC_tran PF00005.22 ETO29156.1 - 6.1e-21 75.1 0.2 1.7e-20 73.7 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 ETO29156.1 - 0.00033 20.7 4.0 0.0076 16.2 1.6 2.6 2 1 0 2 2 2 1 AAA domain Unstab_antitox PF09720.5 ETO29156.1 - 0.011 15.4 0.4 0.032 13.9 0.3 1.8 1 0 0 1 1 1 0 Putative addiction module component ABC2_membrane PF01061.19 ETO29157.1 - 5.6e-31 107.3 19.0 1.3e-26 93.1 6.7 2.3 2 0 0 2 2 2 2 ABC-2 type transporter ABC2_membrane_3 PF12698.2 ETO29157.1 - 1.9e-07 30.4 12.2 5.5e-07 28.9 6.6 2.1 2 0 0 2 2 2 1 ABC-2 family transporter protein Tmemb_cc2 PF10267.4 ETO29157.1 - 0.24 9.9 0.6 0.46 9.0 0.4 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein ABC2_membrane_2 PF12679.2 ETO29157.1 - 0.5 9.1 11.5 0.043 12.6 3.8 2.0 2 1 0 2 2 2 0 ABC-2 family transporter protein zf-RanBP PF00641.13 ETO29158.1 - 0.00052 19.0 0.8 0.00087 18.3 0.6 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others CDK5_activator PF03261.10 ETO29158.1 - 0.057 12.7 0.9 0.065 12.5 0.6 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF572 PF04502.8 ETO29158.1 - 0.071 12.3 5.7 0.08 12.1 3.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2413 PF10310.4 ETO29158.1 - 0.13 11.1 9.1 0.15 10.8 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) zf-HIT PF04438.11 ETO29158.1 - 0.5 10.0 3.0 5.5 6.7 0.1 2.2 1 1 1 2 2 2 0 HIT zinc finger PGA2 PF07543.7 ETO29158.1 - 3.1 7.5 10.3 4.7 6.9 7.2 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 CAP_GLY PF01302.20 ETO29159.1 - 2.9e-05 23.6 0.0 6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain LAG1-DNAbind PF09271.6 ETO29159.1 - 0.078 13.4 1.5 0.1 13.0 1.1 1.2 1 0 0 1 1 1 0 LAG1, DNA binding WD40 PF00400.27 ETO29160.1 - 1.9e-72 236.7 18.3 2.1e-11 43.2 0.0 7.7 7 1 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO29160.1 - 1.9e-11 44.0 0.1 5.8e-06 26.1 0.0 2.9 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO29160.1 - 7.1e-10 37.6 8.5 0.14 10.2 0.0 5.7 1 1 4 5 5 5 4 Nucleoporin Nup120/160 Nbas_N PF15492.1 ETO29160.1 - 0.00047 19.3 0.7 0.12 11.4 0.1 3.4 1 1 3 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Str_synth PF03088.11 ETO29160.1 - 0.004 17.1 0.4 0.25 11.3 0.0 3.4 3 1 2 5 5 5 1 Strictosidine synthase PD40 PF07676.7 ETO29160.1 - 0.041 13.5 1.6 42 3.9 0.0 3.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO29160.1 - 0.075 13.3 0.1 32 4.9 0.0 3.5 2 1 1 3 3 3 0 Resistin CbiQ PF02361.11 ETO29162.1 - 0.00047 19.7 0.0 0.0013 18.3 0.0 1.8 1 1 0 1 1 1 1 Cobalt transport protein YIF1 PF03878.10 ETO29162.1 - 0.28 10.2 10.7 0.031 13.4 2.6 2.2 1 1 0 2 2 2 0 YIF1 EF-hand_1 PF00036.27 ETO29163.1 - 0.0028 16.8 0.1 0.0088 15.2 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 ETO29163.1 - 0.0044 16.7 0.2 0.17 11.8 0.0 2.8 2 1 1 3 3 3 1 EF-hand domain WD40 PF00400.27 ETO29164.1 - 9.6e-75 244.0 13.4 4e-14 51.8 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO29164.1 - 2.8e-12 46.7 0.3 1.5e-06 28.0 0.0 3.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO29164.1 - 7e-07 27.8 0.1 0.00077 17.8 0.0 3.0 1 1 3 4 4 4 3 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO29164.1 - 1.4e-05 24.0 2.3 0.77 8.4 0.1 3.7 1 1 1 2 2 2 2 Nup133 N terminal like PD40 PF07676.7 ETO29164.1 - 1.4e-05 24.5 3.9 11 5.8 0.0 5.9 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO29164.1 - 1.9e-05 23.0 3.4 0.44 8.6 0.0 4.7 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Resistin PF06954.6 ETO29164.1 - 0.0012 19.0 2.2 16 5.8 0.0 4.7 3 1 2 5 5 5 0 Resistin DUF3732 PF12532.3 ETO29164.1 - 0.0077 15.7 0.1 3.7 7.0 0.0 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF3732) DUF1258 PF06869.7 ETO29164.1 - 0.043 12.8 1.3 1 8.3 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1258) DPPIV_N PF00930.16 ETO29164.1 - 0.071 11.6 0.1 8.2 4.8 0.0 3.4 1 1 2 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Proteasome_A_N PF10584.4 ETO29164.1 - 5.7 6.3 9.0 42 3.5 0.0 4.6 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Seryl_tRNA_N PF02403.17 ETO29165.1 - 1.3e-11 44.4 27.2 2.3e-05 24.3 18.6 2.5 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Syntaxin PF00804.20 ETO29165.1 - 0.071 13.2 9.8 0.25 11.5 0.1 2.4 1 1 1 2 2 2 0 Syntaxin DNApol3-delta_C PF09115.5 ETO29165.1 - 0.073 13.1 1.0 0.95 9.5 0.0 2.8 3 0 0 3 3 3 0 DNA polymerase III, delta subunit, C terminal NOD PF06816.8 ETO29165.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 NOTCH protein SlyX PF04102.7 ETO29165.1 - 0.26 11.6 0.3 0.26 11.6 0.2 2.4 2 1 1 3 3 3 0 SlyX Protocadherin PF08374.6 ETO29165.1 - 0.26 10.8 6.9 0.38 10.3 4.8 1.4 1 0 0 1 1 1 0 Protocadherin V_ATPase_I PF01496.14 ETO29165.1 - 0.28 8.9 10.2 0.32 8.7 7.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF948 PF06103.6 ETO29165.1 - 0.35 10.7 4.7 6.3 6.7 0.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DLD PF14878.1 ETO29165.1 - 0.76 9.8 9.2 2.9 8.0 0.1 2.2 2 0 0 2 2 2 0 Death-like domain of SPT6 NPV_P10 PF05531.7 ETO29165.1 - 1.1 9.5 5.9 0.86 9.8 0.4 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Snapin_Pallidin PF14712.1 ETO29165.1 - 1.2 9.5 12.8 4.2 7.7 0.8 2.4 2 1 0 2 2 2 0 Snapin/Pallidin AAA_23 PF13476.1 ETO29165.1 - 3.1 8.0 18.3 4.3 7.6 12.7 1.2 1 0 0 1 1 1 0 AAA domain Tup_N PF08581.5 ETO29165.1 - 4 7.7 16.0 0.68 10.1 6.1 2.3 2 0 0 2 2 2 0 Tup N-terminal DDHD PF02862.12 ETO29165.1 - 4.6 6.9 6.0 6 6.6 4.2 1.2 1 0 0 1 1 1 0 DDHD domain tRNA-synt_2b PF00587.20 ETO29166.1 - 4.8e-32 110.9 0.1 6.1e-32 110.5 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF1336 PF07059.7 ETO29167.1 - 0.022 14.1 0.4 0.049 13.0 0.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1336) Drf_GBD PF06371.8 ETO29168.1 - 0.031 13.6 4.8 0.39 10.0 0.3 2.1 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain Nop14 PF04147.7 ETO29168.1 - 0.032 12.1 8.9 0.04 11.8 6.2 1.1 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.6 ETO29168.1 - 0.18 9.8 3.2 0.26 9.3 2.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SR-25 PF10500.4 ETO29168.1 - 0.54 9.6 15.1 0.057 12.8 2.5 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Acatn PF13000.2 ETO29172.1 - 5.8e-43 147.2 14.1 4.7e-23 81.5 4.9 3.1 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 MFS_1 PF07690.11 ETO29172.1 - 0.0004 19.2 15.5 0.0005 18.9 1.9 2.6 3 0 0 3 3 3 2 Major Facilitator Superfamily DUF912 PF06024.7 ETO29172.1 - 0.18 11.8 1.5 2.5 8.2 0.2 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TLD PF07534.11 ETO29173.1 - 9.5e-14 51.5 0.7 1.9e-13 50.6 0.5 1.5 1 1 0 1 1 1 1 TLD DUF1510 PF07423.6 ETO29173.1 - 6 6.1 14.5 5.3 6.3 5.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Sec1 PF00995.18 ETO29174.1 - 8.9e-66 222.6 0.0 2e-65 221.5 0.0 1.5 1 1 0 1 1 1 1 Sec1 family BEX PF04538.7 ETO29174.1 - 0.033 14.3 1.9 0.099 12.8 1.3 1.8 1 0 0 1 1 1 0 Brain expressed X-linked like family Snf7 PF03357.16 ETO29176.1 - 4.6e-20 71.6 27.9 1.1e-12 47.7 7.3 2.1 2 0 0 2 2 2 2 Snf7 AKNA PF12443.3 ETO29176.1 - 0.004 17.1 8.5 0.011 15.7 2.0 2.4 2 0 0 2 2 2 1 AT-hook-containing transcription factor UPF0193 PF05250.6 ETO29176.1 - 0.0093 15.5 0.5 0.0093 15.5 0.3 1.8 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0193) Rogdi_lz PF10259.4 ETO29176.1 - 0.026 13.6 0.1 0.026 13.6 0.1 1.8 2 1 0 2 2 2 0 Rogdi leucine zipper containing protein DUF4446 PF14584.1 ETO29176.1 - 0.052 13.3 5.2 0.092 12.5 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) DUF1978 PF09321.5 ETO29176.1 - 0.059 12.8 10.2 0.077 12.4 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1978) Hanta_nucleocap PF00846.13 ETO29176.1 - 0.061 12.0 3.6 0.096 11.3 1.0 1.9 2 0 0 2 2 2 0 Hantavirus nucleocapsid protein Tat PF00539.13 ETO29176.1 - 0.082 12.5 1.8 0.3 10.7 0.3 2.4 2 0 0 2 2 2 0 Transactivating regulatory protein (Tat) DUF3993 PF13158.1 ETO29176.1 - 0.15 11.9 3.1 0.11 12.3 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3993) Acyl-CoA_dh_C PF12806.2 ETO29176.1 - 0.19 11.5 2.3 0.85 9.4 0.4 2.4 2 1 0 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like Anti-adapt_IraP PF10796.4 ETO29176.1 - 0.28 11.6 5.7 1.3 9.4 0.8 2.4 2 0 0 2 2 2 0 Sigma-S stabilisation anti-adaptor protein DUF2797 PF10977.3 ETO29176.1 - 0.37 10.3 4.6 0.94 9.0 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2797) Rsbr_N PF08678.5 ETO29176.1 - 0.55 10.1 6.4 0.48 10.2 0.3 2.2 2 0 0 2 2 2 0 Rsbr N terminal Angiomotin_C PF12240.3 ETO29176.1 - 0.81 9.1 8.2 1.3 8.5 1.8 2.1 2 0 0 2 2 2 0 Angiomotin C terminal DUF948 PF06103.6 ETO29176.1 - 0.83 9.5 8.9 0.15 11.9 0.3 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 ETO29176.1 - 1.4 8.5 7.0 1.7 8.1 2.2 2.2 2 0 0 2 2 2 0 IncA protein Hom_end_hint PF05203.11 ETO29176.1 - 1.4 8.6 6.3 0.27 10.9 1.3 1.8 1 1 1 2 2 2 0 Hom_end-associated Hint DUF342 PF03961.8 ETO29176.1 - 1.6 7.0 11.0 0.31 9.4 4.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Fib_alpha PF08702.5 ETO29176.1 - 4.3 7.4 11.0 1.6 8.8 3.0 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CENP-H PF05837.7 ETO29176.1 - 5.8 7.1 13.3 6.6 6.9 4.2 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) F_actin_bind PF08919.5 ETO29176.1 - 6.2 6.5 7.5 14 5.4 0.1 3.1 3 0 0 3 3 3 0 F-actin binding Wbp11 PF09429.5 ETO29177.1 - 0.68 9.9 4.3 0.27 11.2 0.9 1.7 2 0 0 2 2 2 0 WW domain binding protein 11 Thioredoxin PF00085.15 ETO29178.1 - 1.7e-06 27.6 0.1 4.1e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 ETO29178.1 - 4.2e-06 25.6 1.0 5.6e-06 25.2 0.7 1.1 1 0 0 1 1 1 1 Phosducin DUF3857 PF12969.2 ETO29178.1 - 0.073 12.6 1.4 0.16 11.5 0.5 1.8 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3857) SOBP PF15279.1 ETO29179.1 - 0.00024 21.6 28.6 0.00024 21.6 19.9 4.6 2 2 1 4 4 4 1 Sine oculis-binding protein WD40 PF00400.27 ETO29181.1 - 1.5e-15 56.3 6.7 1.2e-06 28.1 0.5 4.3 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO29181.1 - 0.00096 17.3 0.4 0.0045 15.1 0.0 1.8 1 1 1 2 2 2 1 Nucleoporin Nup120/160 WD40 PF00400.27 ETO29182.1 - 1.2e-24 85.2 6.6 6.8e-09 35.2 0.1 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat eIF2A PF08662.6 ETO29182.1 - 0.0095 15.6 0.0 0.016 14.8 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Acyl-CoA_dh_1 PF00441.19 ETO29183.1 - 2.4e-36 125.0 1.0 3.4e-36 124.5 0.7 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 ETO29183.1 - 2.9e-11 43.9 0.0 2.5e-10 40.9 0.0 2.3 1 1 1 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 ETO29183.1 - 1.1e-07 32.1 0.3 1.8e-07 31.4 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 ETO29183.1 - 5.2e-05 22.6 0.0 0.0001 21.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Atx10homo_assoc PF09759.4 ETO29184.1 - 0.0056 16.4 1.8 0.0056 16.4 1.3 3.9 5 0 0 5 5 5 1 Spinocerebellar ataxia type 10 protein domain Proteasom_PSMB PF10508.4 ETO29184.1 - 0.013 13.8 10.3 0.54 8.4 0.0 5.5 5 2 0 5 5 5 0 Proteasome non-ATPase 26S subunit DUF3361 PF11841.3 ETO29184.1 - 0.018 14.7 1.6 0.6 9.8 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF3361) DUF1634 PF07843.6 ETO29184.1 - 0.55 9.8 2.3 1.7 8.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1634) Neurochondrin PF05536.6 ETO29185.1 - 0.026 12.8 0.1 0.037 12.3 0.1 1.2 1 0 0 1 1 1 0 Neurochondrin CDC27 PF09507.5 ETO29188.1 - 2.4 7.2 33.2 0.057 12.6 10.2 2.3 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 EF-hand_7 PF13499.1 ETO29189.1 - 1.2e-13 50.9 7.1 2.3e-10 40.4 0.5 3.7 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO29189.1 - 6.6e-13 47.3 2.9 0.032 14.0 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.27 ETO29189.1 - 1.2e-10 39.8 9.1 0.00012 21.1 0.1 4.5 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.1 ETO29189.1 - 2.4e-08 32.9 0.5 0.2 11.0 0.0 4.0 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 ETO29189.1 - 2.2e-05 23.9 7.8 0.0025 17.3 0.6 3.5 2 2 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 ETO29189.1 - 0.00012 22.0 9.6 0.00047 20.1 2.5 3.4 2 1 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Terminase_6 PF03237.10 ETO29191.1 - 9.6e-05 21.3 0.0 0.00014 20.7 0.0 1.3 1 0 0 1 1 1 1 Terminase-like family DENN PF02141.16 ETO29192.1 - 1.1e-27 96.9 1.5 2.7e-27 95.6 1.0 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 ETO29192.1 - 3e-12 46.4 7.9 5.8e-12 45.5 5.5 1.4 1 0 0 1 1 1 1 dDENN domain DUF3915 PF13054.1 ETO29192.1 - 0.42 10.5 6.2 1.2 9.0 0.8 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) SR-25 PF10500.4 ETO29192.1 - 2.8 7.3 12.6 4.5 6.6 8.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Mito_carr PF00153.22 ETO29193.1 - 1.3e-15 56.8 0.0 1.4e-15 56.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein WD40 PF00400.27 ETO29194.1 - 3.9e-121 391.1 44.0 1.4e-14 53.2 0.1 12.1 12 0 0 12 12 12 12 WD domain, G-beta repeat eIF2A PF08662.6 ETO29194.1 - 8.2e-19 68.0 0.0 1e-05 25.3 0.0 5.1 1 1 4 6 6 6 6 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO29194.1 - 4.9e-10 38.1 14.4 0.069 11.2 0.1 7.8 2 2 4 6 6 6 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO29194.1 - 6.9e-10 38.7 0.9 0.0011 18.4 0.6 4.6 1 1 1 2 2 2 2 PQQ-like domain DUF727 PF05303.7 ETO29194.1 - 1.3e-06 28.1 0.4 1.6 8.5 0.0 5.7 4 2 1 6 6 6 2 Protein of unknown function (DUF727) PD40 PF07676.7 ETO29194.1 - 3.8e-05 23.2 19.2 1.1 9.0 0.0 8.5 9 0 0 9 9 9 1 WD40-like Beta Propeller Repeat BBS2_Mid PF14783.1 ETO29194.1 - 4e-05 23.3 3.4 5.4 6.8 0.0 6.7 3 2 4 7 7 7 1 Ciliary BBSome complex subunit 2, middle region Cytochrom_D1 PF02239.11 ETO29194.1 - 0.0003 19.2 5.3 0.65 8.2 0.1 3.9 1 1 3 5 5 5 2 Cytochrome D1 heme domain NYD-SP28_assoc PF14775.1 ETO29194.1 - 0.00044 19.8 1.2 16 5.3 0.0 6.6 8 0 0 8 8 7 0 Sperm tail C-terminal domain Gmad1 PF10647.4 ETO29194.1 - 0.0019 17.6 0.0 1.5 8.1 0.0 3.7 2 1 1 3 3 3 1 Lipoprotein LpqB beta-propeller domain Cofilin_ADF PF00241.15 ETO29194.1 - 0.0043 16.9 0.6 17 5.3 0.0 5.2 5 1 1 6 6 5 0 Cofilin/tropomyosin-type actin-binding protein DUF3312 PF11768.3 ETO29194.1 - 0.0085 14.3 0.1 7.8 4.5 0.0 3.9 3 1 2 5 5 5 1 Protein of unknown function (DUF3312) Proteasome_A_N PF10584.4 ETO29194.1 - 3.5 7.0 22.6 27 4.1 0.0 7.5 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature Helicase_C PF00271.26 ETO29195.1 - 3.1e-14 52.5 0.0 7.1e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CEP19 PF14933.1 ETO29195.1 - 0.74 10.0 6.9 0.35 11.1 2.4 2.0 2 0 0 2 2 2 0 CEP19-like protein RGS PF00615.14 ETO29196.1 - 1.8e-05 24.8 2.8 2.7e-05 24.2 1.9 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain Ctr PF04145.10 ETO29197.1 - 0.02 14.9 0.1 0.02 14.9 0.0 2.3 1 1 1 2 2 2 0 Ctr copper transporter family Herpes_LMP1 PF05297.6 ETO29197.1 - 1.7 7.4 5.8 2.6 6.8 4.0 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Exonuc_VII_L PF02601.10 ETO29197.1 - 3.7 6.6 11.6 4.3 6.4 8.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF605 PF04652.11 ETO29198.1 - 1.3e-48 166.3 12.1 2.3e-48 165.5 8.4 1.3 1 1 0 1 1 1 1 Vta1 like TMEM171 PF15471.1 ETO29198.1 - 0.18 10.5 2.7 0.29 9.8 1.9 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Secretin_N_2 PF07655.8 ETO29200.1 - 0.00085 19.6 11.8 0.002 18.4 8.2 1.6 1 0 0 1 1 1 1 Secretin N-terminal domain BTB_2 PF02214.17 ETO29200.1 - 0.0049 17.0 1.1 1.7 8.9 0.0 2.7 2 1 1 3 3 3 2 BTB/POZ domain MFMR PF07777.6 ETO29200.1 - 0.027 14.4 1.4 0.027 14.4 1.0 1.6 2 0 0 2 2 2 0 G-box binding protein MFMR Rad60-SLD PF11976.3 ETO29201.1 - 0.002 17.7 0.1 0.002 17.7 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like RNA_pol_Rpb1_5 PF04998.12 ETO29201.1 - 0.52 9.5 8.0 1.4 8.0 5.5 1.6 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 5 HNH PF01844.18 ETO29202.1 - 0.025 14.4 0.5 0.052 13.4 0.3 1.6 1 1 0 1 1 1 0 HNH endonuclease PyrI_C PF02748.10 ETO29202.1 - 0.057 12.8 0.6 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF607 PF04678.8 ETO29202.1 - 2.9 7.7 7.5 1 9.2 3.4 1.6 1 1 1 2 2 2 0 Protein of unknown function, DUF607 DUF3573 PF12097.3 ETO29202.1 - 3.3 6.2 8.2 3.8 6.0 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Hid1 PF12722.2 ETO29202.1 - 4.9 4.7 19.7 5.8 4.4 13.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1509 PF07420.6 ETO29202.1 - 7.6 5.7 12.0 0.55 9.4 4.9 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1509) DUF2146 PF10220.4 ETO29202.1 - 9.2 4.1 15.0 11 3.8 10.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Kelch_6 PF13964.1 ETO29203.1 - 0.0004 20.4 1.4 8.9 6.6 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO29203.1 - 0.0017 18.0 3.1 3.9 7.3 0.1 4.3 3 1 1 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO29203.1 - 3.5 7.4 4.9 1.9 8.3 0.2 2.8 4 0 0 4 4 4 0 Galactose oxidase, central domain DUF3456 PF11938.3 ETO29205.1 - 0.0013 18.7 2.9 0.0024 17.8 2.0 1.4 1 0 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP Sod_Fe_N PF00081.17 ETO29205.1 - 0.24 11.6 1.3 0.45 10.7 0.0 2.1 3 0 0 3 3 3 0 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF3674 PF12426.3 ETO29205.1 - 1.3 8.5 4.3 2.2 7.7 0.0 2.9 3 0 0 3 3 3 0 RNA dependent RNA polymerase PI3K_p85B PF02192.11 ETO29206.1 - 0.024 14.0 0.0 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain Ras PF00071.17 ETO29207.1 - 8.3e-21 74.0 0.0 1.1e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Arf PF00025.16 ETO29207.1 - 1.1e-05 24.7 0.0 1.3e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 ETO29207.1 - 2.7e-05 24.6 0.0 7.8e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 ETO29207.1 - 0.031 13.7 0.0 0.04 13.3 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain ArgK PF03308.11 ETO29207.1 - 0.088 11.5 0.0 0.099 11.4 0.0 1.1 1 0 0 1 1 1 0 ArgK protein tRNA-synt_1f PF01921.13 ETO29208.1 - 0.084 11.5 0.1 0.14 10.7 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) Fer2_2 PF01799.15 ETO29208.1 - 0.13 12.2 0.0 1.1 9.2 0.0 2.2 2 1 0 2 2 2 0 [2Fe-2S] binding domain DUF4625 PF15418.1 ETO29209.1 - 0.047 13.8 0.2 0.087 12.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) Orthopox_B11R PF07033.6 ETO29212.1 - 0.25 10.8 4.3 0.14 11.6 1.1 2.0 2 0 0 2 2 2 0 Orthopoxvirus B11R protein RVT_1 PF00078.22 ETO29214.1 - 2.3e-10 40.1 0.1 3e-08 33.2 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) PUB PF09409.5 ETO29215.1 - 7.2e-05 22.4 1.2 0.00064 19.4 0.9 2.6 1 1 0 1 1 1 1 PUB domain ART PF01129.13 ETO29215.1 - 0.00057 19.0 0.0 0.0011 18.1 0.0 1.5 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase Thioredoxin_2 PF13098.1 ETO29215.1 - 0.73 10.0 5.3 0.53 10.4 0.5 2.9 2 0 0 2 2 2 0 Thioredoxin-like domain NDK PF00334.14 ETO29216.1 - 1.1e-24 86.7 0.0 1.6e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase ComK PF06338.6 ETO29216.1 - 0.11 11.8 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 ComK protein TLP-20 PF06088.6 ETO29217.1 - 6.6 6.3 15.8 2.1 7.9 3.9 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Uds1 PF15456.1 ETO29217.1 - 7.3 6.6 9.0 7.4 6.5 2.1 2.3 2 0 0 2 2 2 0 Up-regulated During Septation CAF1 PF04857.15 ETO29218.1 - 4.3e-53 180.3 1.1 1.6e-42 145.6 0.5 2.9 2 2 1 3 3 3 2 CAF1 family ribonuclease AAA_18 PF13238.1 ETO29220.1 - 5.3 7.3 7.6 4.8 7.5 0.3 3.1 3 1 0 3 3 3 0 AAA domain HECT_2 PF09814.4 ETO29221.1 - 1.3e-11 43.8 3.5 2.6e-11 42.8 2.4 1.5 1 1 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Chordopox_RPO7 PF05864.7 ETO29221.1 - 0.027 14.5 2.2 3.1 7.9 0.0 3.2 3 0 0 3 3 3 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) zf-BED PF02892.10 ETO29221.1 - 0.058 13.1 0.5 0.29 10.9 0.0 2.3 2 0 0 2 2 2 0 BED zinc finger zinc_ribbon_2 PF13240.1 ETO29221.1 - 0.51 9.9 3.4 28 4.3 0.0 3.6 3 0 0 3 3 3 0 zinc-ribbon domain FUSC_2 PF13515.1 ETO29222.1 - 0.039 13.8 0.4 0.064 13.1 0.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein-like DUF2762 PF10960.3 ETO29222.1 - 0.068 12.8 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) ER_lumen_recept PF00810.13 ETO29222.1 - 0.092 13.2 3.3 0.2 12.1 2.3 1.6 1 1 0 1 1 1 0 ER lumen protein retaining receptor Fumarate_red_C PF02300.12 ETO29222.1 - 0.12 12.2 3.1 0.21 11.4 2.1 1.3 1 0 0 1 1 1 0 Fumarate reductase subunit C P12 PF12669.2 ETO29222.1 - 0.18 12.0 0.3 0.18 12.0 0.2 1.8 2 0 0 2 2 2 0 Virus attachment protein p12 family GSHPx PF00255.14 ETO29224.1 - 0.05 12.9 0.1 0.089 12.1 0.1 1.4 1 0 0 1 1 1 0 Glutathione peroxidase Pkinase_Tyr PF07714.12 ETO29225.1 - 1.4e-71 240.5 0.0 1.8e-71 240.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 ETO29225.1 - 7e-56 189.2 0.0 9.5e-56 188.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain YrbL-PhoP_reg PF10707.4 ETO29225.1 - 0.0027 17.0 0.1 0.012 15.0 0.0 2.0 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 ETO29225.1 - 0.0033 16.5 0.1 0.0063 15.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3485 PF11984.3 ETO29226.1 - 0.04 12.9 0.0 0.17 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3485) DUF4094 PF13334.1 ETO29227.1 - 0.005 17.2 0.3 0.005 17.2 0.2 4.6 3 1 1 4 4 4 1 Domain of unknown function (DUF4094) CD20 PF04103.10 ETO29227.1 - 0.077 12.9 0.2 1.4 8.8 0.0 2.6 2 0 0 2 2 2 0 CD20-like family Tetraspannin PF00335.15 ETO29227.1 - 0.18 11.0 10.6 0.23 10.6 0.1 3.4 3 1 0 3 3 3 0 Tetraspanin family GA PF01468.12 ETO29228.1 - 0.15 12.2 2.4 0.62 10.2 1.7 2.1 1 0 0 1 1 1 0 GA module DUF2457 PF10446.4 ETO29230.1 - 0.0031 16.3 18.0 0.0031 16.3 12.5 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) CDC45 PF02724.9 ETO29230.1 - 0.13 10.2 13.2 0.18 9.8 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 ETO29230.1 - 0.33 8.8 15.5 0.5 8.2 10.8 1.2 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.7 ETO29230.1 - 0.49 9.4 16.3 0.87 8.6 11.3 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT UAA PF08449.6 ETO29232.1 - 1.2e-25 90.1 4.2 1.3e-25 89.9 2.9 1.0 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 ETO29232.1 - 2.2e-05 24.6 5.6 9.5e-05 22.5 0.0 2.5 3 0 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 ETO29232.1 - 0.0001 22.2 0.3 0.0001 22.2 0.2 2.6 2 1 0 2 2 2 1 EamA-like transporter family PqiA PF04403.8 ETO29232.1 - 0.019 14.5 0.1 0.019 14.5 0.1 1.6 2 0 0 2 2 2 0 Paraquat-inducible protein A TMEM107 PF14995.1 ETO29232.1 - 0.08 13.0 0.7 0.08 13.0 0.5 1.9 1 1 0 1 1 1 0 Transmembrane protein Mem_trans PF03547.13 ETO29233.1 - 5.7 5.1 12.0 3.4 5.8 1.7 3.2 3 0 0 3 3 3 0 Membrane transport protein Pyr_redox PF00070.22 ETO29234.1 - 1.2e-06 28.7 0.1 2.3e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETO29234.1 - 5.8e-06 26.3 0.0 1.6e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETO29234.1 - 0.0014 17.5 0.0 0.0024 16.8 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 ETO29234.1 - 0.031 14.3 0.5 0.2 11.7 0.0 2.2 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF2540 PF10802.3 ETO29234.1 - 0.15 11.7 2.2 0.14 11.8 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2540) DUF1980 PF09323.5 ETO29234.1 - 0.31 10.7 4.6 0.12 12.1 1.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) CDP-OH_P_transf PF01066.16 ETO29236.1 - 4.7e-12 46.0 6.3 4.7e-12 46.0 4.4 1.6 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF3312 PF11768.3 ETO29239.1 - 0.00086 17.6 0.1 0.0023 16.2 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3312) DUF912 PF06024.7 ETO29239.1 - 0.094 12.7 0.8 0.61 10.1 0.1 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3670 PF12419.3 ETO29241.1 - 0.02 14.3 0.0 0.19 11.1 0.0 2.0 1 1 0 1 1 1 0 SNF2 Helicase protein UDP-g_GGTase PF06427.6 ETO29241.1 - 0.088 12.1 0.2 0.45 9.7 0.1 1.8 1 1 1 2 2 2 0 UDP-glucose:Glycoprotein Glucosyltransferase PBP1_TM PF14812.1 ETO29242.1 - 7.4 6.9 15.9 8.3 6.7 11.0 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Herpes_DNAp_acc PF04929.7 ETO29243.1 - 0.79 8.6 18.1 0.84 8.5 12.5 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Zip PF02535.17 ETO29243.1 - 1 8.2 10.5 1.1 8.2 7.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3807 PF12720.2 ETO29243.1 - 5.3 7.1 27.9 6.1 6.9 19.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF4604 PF15377.1 ETO29243.1 - 5.3 7.2 32.6 8.7 6.5 22.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) DUF4569 PF15133.1 ETO29243.1 - 5.8 6.2 14.5 6.4 6.0 10.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) RCR PF12273.3 ETO29243.1 - 5.8 7.4 10.5 6.7 7.2 7.3 1.2 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Ebola_NP PF05505.7 ETO29243.1 - 7 4.5 16.8 7.6 4.4 11.6 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein Neisseria_TspB PF05616.8 ETO29243.1 - 9.5 4.4 11.9 11 4.2 8.3 1.0 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein AAA PF00004.24 ETO29244.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETO29244.1 - 0.13 12.4 0.0 0.34 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain HA2 PF04408.18 ETO29245.1 - 8.4e-19 67.4 0.0 2.3e-18 66.0 0.0 1.7 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 ETO29245.1 - 2e-10 40.3 0.0 4.5e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Exo_endo_phos_2 PF14529.1 ETO29246.1 - 6.2e-09 35.4 0.1 7.7e-09 35.1 0.1 1.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Metallothio_11 PF02066.10 ETO29247.1 - 0.45 10.4 3.5 0.25 11.2 0.5 2.0 1 1 1 2 2 2 0 Metallothionein family 11 ATP-synt_S1 PF05827.7 ETO29248.1 - 0.01 15.1 0.3 0.013 14.8 0.2 1.2 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) DEAD PF00270.24 ETO29249.1 - 8e-10 38.4 0.1 1.5e-09 37.5 0.1 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 ETO29249.1 - 6.7e-07 29.5 0.1 1.3e-06 28.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 ETO29249.1 - 0.00019 20.5 0.2 0.00043 19.3 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 ETO29249.1 - 0.00027 19.9 0.0 0.00052 19.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DAP3 PF10236.4 ETO29249.1 - 0.00064 18.7 0.2 0.0013 17.6 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 AAA_14 PF13173.1 ETO29249.1 - 0.0016 18.3 0.1 0.55 10.1 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 ETO29249.1 - 0.0018 17.7 0.2 0.0058 16.1 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain SR-25 PF10500.4 ETO29249.1 - 0.0019 17.6 8.2 0.0027 17.2 5.7 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein AAA_10 PF12846.2 ETO29249.1 - 0.0059 16.0 0.0 0.036 13.5 0.0 1.8 1 1 1 2 2 2 1 AAA-like domain ResIII PF04851.10 ETO29249.1 - 0.011 15.5 1.3 0.38 10.5 0.0 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF258 PF03193.11 ETO29249.1 - 0.011 14.8 0.3 0.19 10.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 KaiC PF06745.8 ETO29249.1 - 0.016 14.2 0.0 0.031 13.3 0.0 1.5 1 0 0 1 1 1 0 KaiC G-alpha PF00503.15 ETO29249.1 - 0.026 13.2 6.2 0.015 13.9 2.1 2.0 2 1 0 2 2 2 0 G-protein alpha subunit AAA_19 PF13245.1 ETO29249.1 - 0.034 13.8 0.0 0.087 12.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Helicase_RecD PF05127.9 ETO29249.1 - 0.035 13.7 0.2 0.081 12.5 0.0 1.7 2 0 0 2 2 2 0 Helicase PhoH PF02562.11 ETO29249.1 - 0.046 12.9 0.0 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_23 PF13476.1 ETO29249.1 - 0.046 14.0 0.3 0.046 14.0 0.2 2.2 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.1 ETO29249.1 - 0.069 12.7 0.0 0.14 11.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 ETO29249.1 - 0.075 13.5 0.2 0.25 11.8 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein AAA_25 PF13481.1 ETO29249.1 - 0.14 11.4 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETO29249.1 - 0.36 10.8 5.2 0.23 11.4 0.8 2.6 2 1 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 ETO29249.1 - 0.46 10.7 2.9 0.53 10.5 0.1 2.3 2 1 1 3 3 3 0 ABC transporter VWA_3 PF13768.1 ETO29251.1 - 1.4e-15 57.3 0.0 1.8e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 ETO29251.1 - 1.2e-13 51.5 0.0 1.6e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 ETO29251.1 - 1e-12 48.1 0.0 1.3e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 ETO29251.1 - 0.0002 21.2 0.0 0.00043 20.1 0.0 1.5 1 1 0 1 1 1 1 vWA found in TerF C terminus Copine PF07002.11 ETO29251.1 - 0.00024 20.8 0.0 0.0003 20.5 0.0 1.2 1 0 0 1 1 1 1 Copine VWA_CoxE PF05762.9 ETO29251.1 - 0.057 12.5 0.0 0.077 12.1 0.0 1.2 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein REC114-like PF15165.1 ETO29252.1 - 5.3e-05 23.0 0.5 0.0021 17.8 0.1 2.2 1 1 1 2 2 2 2 Meiotic recombination protein REC114-like DUF4378 PF14309.1 ETO29253.1 - 0.00033 20.7 1.0 0.00038 20.5 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4378) RGS PF00615.14 ETO29255.1 - 5.4e-10 39.3 0.6 1.9e-09 37.6 0.1 2.1 2 1 0 2 2 2 1 Regulator of G protein signaling domain NESP55 PF06390.7 ETO29256.1 - 0.0024 17.3 0.2 0.0035 16.7 0.2 1.4 1 0 0 1 1 1 1 Neuroendocrine-specific golgi protein P55 (NESP55) ATS PF15445.1 ETO29256.1 - 0.016 14.3 9.1 0.023 13.7 6.3 1.3 1 0 0 1 1 1 0 acidic terminal segments, variant surface antigen of PfEMP1 ERM PF00769.14 ETO29256.1 - 0.084 12.3 2.2 0.12 11.9 1.5 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Pap_E4 PF02711.9 ETO29256.1 - 2.1 9.1 11.3 8.7e+02 0.8 7.8 2.6 1 1 0 1 1 1 0 E4 protein 7TM_GPCR_Srh PF10318.4 ETO29257.1 - 0.0091 14.8 1.1 0.016 14.0 0.8 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh PH PF00169.24 ETO29258.1 - 0.00047 20.3 4.6 0.0079 16.3 0.0 2.7 2 1 0 2 2 2 1 PH domain PH_11 PF15413.1 ETO29258.1 - 0.0085 16.3 1.0 0.15 12.3 0.0 2.4 2 1 0 2 2 2 1 Pleckstrin homology domain SAM_1 PF00536.25 ETO29260.1 - 0.008 16.3 0.1 0.027 14.6 0.1 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PEP-utilisers_N PF05524.8 ETO29260.1 - 0.0094 15.7 2.7 0.52 10.1 0.9 2.9 2 1 1 3 3 3 1 PEP-utilising enzyme, N-terminal Actin PF00022.14 ETO29261.1 - 1.7e-84 283.5 0.0 1.9e-84 283.4 0.0 1.0 1 0 0 1 1 1 1 Actin TMEM125 PF15109.1 ETO29262.1 - 0.0027 17.7 1.3 0.0048 16.9 0.9 1.4 1 0 0 1 1 1 1 TMEM125 protein family RGS PF00615.14 ETO29263.1 - 1.4e-05 25.1 3.2 0.029 14.4 1.8 3.5 2 1 0 2 2 2 1 Regulator of G protein signaling domain MSC PF09402.5 ETO29263.1 - 0.0089 14.7 0.1 0.018 13.7 0.0 1.5 2 0 0 2 2 2 1 Man1-Src1p-C-terminal domain Pex24p PF06398.6 ETO29263.1 - 0.1 11.3 1.5 0.11 11.3 0.0 1.7 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Brr6_like_C_C PF10104.4 ETO29263.1 - 1.6 8.2 5.1 0.13 11.7 0.2 1.8 2 0 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain Mannosyl_trans3 PF11051.3 ETO29264.1 - 8e-19 68.0 0.2 1.4e-18 67.1 0.1 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.11 ETO29264.1 - 0.015 15.0 0.1 0.044 13.5 0.0 1.8 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Kelch_6 PF13964.1 ETO29265.1 - 0.016 15.3 0.2 28 5.0 0.1 3.9 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.1 ETO29265.1 - 0.028 14.3 0.4 13 5.8 0.1 3.8 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.1 ETO29265.1 - 0.19 11.5 1.6 31 4.4 0.0 3.8 4 0 0 4 4 4 0 Galactose oxidase, central domain WD40 PF00400.27 ETO29266.1 - 2.5e-51 169.7 3.5 3.3e-11 42.6 0.0 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO29266.1 - 2.1e-05 22.8 1.4 0.037 12.1 0.0 3.2 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO29266.1 - 0.00075 17.9 2.0 0.067 11.4 0.0 3.0 1 1 2 3 3 3 1 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO29266.1 - 0.0056 15.8 0.3 3.3 6.7 0.0 2.8 1 1 2 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 ETO29266.1 - 0.033 13.5 0.1 0.39 10.0 0.0 2.7 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Nucleoporin_N PF08801.6 ETO29266.1 - 0.038 12.7 4.9 0.49 9.0 1.0 3.1 2 1 1 3 3 3 0 Nup133 N terminal like DUF1258 PF06869.7 ETO29266.1 - 0.043 12.8 0.1 1.2 8.1 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1258) Methyltransf_3 PF01596.12 ETO29266.1 - 0.046 12.7 0.0 0.086 11.8 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase Formyl_trans_C PF02911.13 ETO29266.1 - 0.085 12.9 0.1 3.7 7.7 0.0 3.0 2 1 0 2 2 2 0 Formyl transferase, C-terminal domain Tubulin PF00091.20 ETO29267.1 - 3.4e-48 164.3 1.0 1.9e-47 161.9 0.7 2.0 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO29267.1 - 1.7e-34 118.5 0.3 4.8e-34 117.1 0.3 1.8 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 ETO29267.1 - 0.02 14.3 1.0 0.86 9.0 0.0 2.3 2 0 0 2 2 2 0 Tubulin domain Tubulin PF00091.20 ETO29268.1 - 1.2e-54 185.4 0.0 2.2e-54 184.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO29268.1 - 1.7e-18 66.8 0.2 7.2e-18 64.8 0.1 2.2 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 ETO29268.1 - 8.2e-05 22.6 1.5 0.00031 20.7 0.0 2.6 3 0 0 3 3 3 1 Misato Segment II tubulin-like domain DUF3959 PF13105.1 ETO29268.1 - 0.014 14.7 0.0 0.014 14.7 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3959) G-alpha PF00503.15 ETO29269.1 - 6.5e-32 110.6 0.1 8.6e-32 110.2 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit DUF4043 PF13252.1 ETO29269.1 - 0.0022 17.0 0.2 0.0031 16.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4043) Arf PF00025.16 ETO29269.1 - 0.026 13.7 0.0 0.036 13.2 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family ABC_tran PF00005.22 ETO29269.1 - 0.029 14.6 0.0 0.047 13.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 ETO29269.1 - 0.089 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.15 ETO29270.1 - 5.4e-14 51.6 7.0 3.2e-13 49.1 4.9 1.9 1 1 0 1 1 1 1 G-protein alpha subunit DUF4243 PF14027.1 ETO29270.1 - 1.2 8.5 5.3 0.3 10.4 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4243) DUF2207 PF09972.4 ETO29271.1 - 0.003 16.2 5.1 0.0034 16.0 3.5 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) SUR7 PF06687.7 ETO29271.1 - 0.0045 16.5 3.5 0.0056 16.2 2.4 1.2 1 0 0 1 1 1 1 SUR7/PalI family UPF0233 PF06781.7 ETO29271.1 - 0.0078 15.8 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0233) DUF106 PF01956.11 ETO29271.1 - 0.029 13.9 4.6 0.037 13.5 3.2 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 Peroxin-13_N PF04088.8 ETO29271.1 - 0.058 13.3 3.1 0.086 12.7 2.1 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region HSCB_C PF07743.8 ETO29272.1 - 3.2e-12 46.7 2.7 6.4e-12 45.7 1.9 1.5 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 ETO29272.1 - 2.3e-07 30.4 0.6 4.7e-07 29.4 0.4 1.6 1 0 0 1 1 1 1 DnaJ domain DUF3763 PF12592.3 ETO29272.1 - 0.0072 15.9 1.1 0.019 14.5 0.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3763) RRM_1 PF00076.17 ETO29273.1 - 3.5e-31 106.6 0.1 3.1e-14 52.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO29273.1 - 4.2e-26 90.7 0.1 4.5e-11 42.5 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO29273.1 - 5.6e-15 54.9 0.2 1.8e-07 30.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 ETO29273.1 - 2.6e-07 30.5 34.2 5.1e-07 29.5 23.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) DUF3439 PF11921.3 ETO29273.1 - 0.002 17.8 2.8 0.0021 17.7 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) MIP-T3 PF10243.4 ETO29273.1 - 0.0056 15.2 21.9 0.0079 14.7 15.2 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Rad60-SLD PF11976.3 ETO29273.1 - 0.016 14.8 0.2 0.038 13.6 0.2 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 ETO29273.1 - 0.048 13.0 0.1 0.1 12.0 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin family DUF4407 PF14362.1 ETO29273.1 - 1.5 7.7 7.2 2.3 7.1 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) fn3 PF00041.16 ETO29274.1 - 2e-08 34.2 4.8 3.4e-06 27.1 0.0 3.7 3 0 0 3 3 3 2 Fibronectin type III domain UPF0102 PF02021.12 ETO29274.1 - 0.02 14.7 0.1 0.067 13.1 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein family UPF0102 Ras PF00071.17 ETO29275.1 - 1.2e-27 96.3 1.0 7.3e-13 48.2 0.1 2.2 2 0 0 2 2 2 2 Ras family Miro PF08477.8 ETO29275.1 - 2e-13 50.9 0.2 5.1e-13 49.5 0.2 1.7 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 ETO29275.1 - 2.6e-06 27.3 0.1 4.3e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF4E PF01652.13 ETO29276.1 - 4.8e-46 156.2 2.0 5.7e-46 156.0 1.4 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Ank_2 PF12796.2 ETO29277.1 - 1.2e-25 89.5 2.0 2.1e-13 50.3 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO29277.1 - 5.2e-20 71.0 0.5 7.1e-10 38.8 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 ETO29277.1 - 3.4e-19 67.6 0.9 8e-07 28.5 0.0 5.2 5 1 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 ETO29277.1 - 3.7e-15 54.5 0.2 0.0011 18.9 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 ETO29277.1 - 2.7e-14 53.2 0.1 1.3e-05 25.5 0.0 3.3 2 1 0 3 3 3 2 Ankyrin repeats (many copies) RNA_pol_Rpb1_7 PF04990.7 ETO29278.1 - 0.09 12.4 0.5 0.11 12.1 0.3 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 7 Integrase_AP2 PF14657.1 ETO29279.1 - 6.2 6.6 6.2 4.8 7.0 0.8 2.6 3 0 0 3 3 3 0 AP2-like DNA-binding integrase domain Tctex-1 PF03645.8 ETO29280.1 - 5.3e-27 93.6 0.6 6e-27 93.4 0.4 1.0 1 0 0 1 1 1 1 Tctex-1 family Glucosaminidase PF01832.15 ETO29281.1 - 0.11 12.6 0.3 0.13 12.3 0.2 1.1 1 0 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase MFS_1 PF07690.11 ETO29282.1 - 1.6e-11 43.5 1.4 2e-09 36.6 2.4 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 ETO29282.1 - 7.6e-07 28.8 1.6 1.4e-06 27.9 1.1 1.5 1 0 0 1 1 1 1 MFS_1 like family ATG22 PF11700.3 ETO29282.1 - 1.2e-05 23.9 0.0 1.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Ycf1 PF05758.7 ETO29282.1 - 0.0004 18.2 0.1 0.00047 18.0 0.1 1.2 1 0 0 1 1 1 1 Ycf1 MFS_2 PF13347.1 ETO29282.1 - 0.0027 16.1 2.6 0.0027 16.1 1.8 1.9 2 0 0 2 2 2 1 MFS/sugar transport protein YABBY PF04690.8 ETO29282.1 - 0.013 15.7 2.6 0.013 15.7 1.8 1.9 2 0 0 2 2 2 0 YABBY protein SelP_N PF04592.9 ETO29282.1 - 0.015 14.7 9.5 0.035 13.5 6.6 1.7 1 0 0 1 1 1 0 Selenoprotein P, N terminal region NicO PF03824.11 ETO29282.1 - 0.057 12.7 0.6 0.1 11.8 0.4 1.4 1 0 0 1 1 1 0 High-affinity nickel-transport protein FAM176 PF14851.1 ETO29282.1 - 0.066 12.8 0.7 0.17 11.5 0.5 1.8 1 0 0 1 1 1 0 FAM176 family G0-G1_switch_2 PF15103.1 ETO29282.1 - 0.11 12.7 8.4 0.52 10.5 2.9 3.1 1 1 1 2 2 2 0 G0/G1 switch protein 2 BAF1_ABF1 PF04684.8 ETO29282.1 - 0.14 10.9 21.6 0.23 10.2 15.0 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Pex24p PF06398.6 ETO29282.1 - 0.76 8.5 4.9 0.58 8.8 1.4 2.1 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin Mem_trans PF03547.13 ETO29282.1 - 0.95 7.6 7.1 1.2 7.2 4.3 1.5 1 1 0 1 1 1 0 Membrane transport protein FAM60A PF15396.1 ETO29282.1 - 1.3 8.7 11.9 0.071 12.8 3.7 2.0 2 0 0 2 2 2 0 Protein Family FAM60A Ly49 PF08391.5 ETO29282.1 - 4.6 7.3 12.3 22 5.2 8.5 2.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Neur_chan_memb PF02932.11 ETO29282.1 - 5.2 6.8 13.6 11 5.7 7.5 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region COPIIcoated_ERV PF07970.7 ETO29283.1 - 1.8e-20 73.5 0.2 3.1e-20 72.7 0.1 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter Thioredoxin PF00085.15 ETO29283.1 - 2.5e-17 62.4 0.5 2.3e-09 36.8 0.1 2.9 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_8 PF13905.1 ETO29283.1 - 2.9e-06 27.2 0.9 0.00025 21.1 0.0 3.4 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.1 ETO29283.1 - 0.0017 18.5 0.3 0.015 15.5 0.2 2.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 ETO29283.1 - 0.01 15.8 0.1 0.037 14.0 0.0 2.0 1 0 0 1 1 1 0 Thioredoxin-like ERGIC_N PF13850.1 ETO29283.1 - 0.017 15.1 0.1 0.046 13.6 0.1 1.8 1 0 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) NTF2 PF02136.15 ETO29283.1 - 0.036 14.4 0.1 0.14 12.5 0.0 2.0 1 1 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain PI3K_rbd PF00794.13 ETO29284.1 - 0.00026 20.9 0.7 0.00075 19.4 0.5 1.8 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain SPRY PF00622.23 ETO29285.1 - 1.2e-22 80.2 0.3 6.7e-22 77.8 0.0 2.3 2 0 0 2 2 2 1 SPRY domain zf-RanBP PF00641.13 ETO29285.1 - 1.2e-06 27.5 9.5 5.1e-05 22.2 2.3 2.6 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.2 ETO29285.1 - 0.83 9.5 7.2 3.1 7.6 5.0 2.1 1 0 0 1 1 1 0 Double zinc ribbon LMBR1 PF04791.11 ETO29286.1 - 0.00087 17.9 0.7 0.00087 17.9 0.5 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein Mem_trans PF03547.13 ETO29286.1 - 0.63 8.2 2.4 0.63 8.2 1.7 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF1777 PF08648.7 ETO29288.1 - 0.0052 16.5 5.1 0.0064 16.2 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) DUF1510 PF07423.6 ETO29288.1 - 0.14 11.5 15.8 0.19 11.0 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF572 PF04502.8 ETO29288.1 - 0.76 8.9 16.9 0.91 8.6 11.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4604 PF15377.1 ETO29288.1 - 0.93 9.6 19.6 2.1 8.5 13.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) SPATIAL PF15256.1 ETO29288.1 - 1.1 9.2 7.2 0.31 11.0 3.1 1.4 2 0 0 2 2 2 0 SPATIAL TEX19 PF15553.1 ETO29288.1 - 2.1 8.2 5.2 1.2 8.9 2.3 1.6 2 0 0 2 2 2 0 Testis-expressed protein 19 Ycf1 PF05758.7 ETO29288.1 - 2.2 5.9 8.1 2.3 5.8 5.6 1.2 1 0 0 1 1 1 0 Ycf1 Glyco_hydro_2 PF00703.16 ETO29288.1 - 3.1 8.2 6.5 2 8.8 3.1 1.8 2 1 0 2 2 2 0 Glycosyl hydrolases family 2 TMEM237 PF15383.1 ETO29288.1 - 3.1 6.8 6.5 5 6.1 4.5 1.3 1 0 0 1 1 1 0 Transmembrane protein 237 DUF4551 PF15087.1 ETO29288.1 - 5.1 5.3 10.6 5.7 5.1 7.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CDC45 PF02724.9 ETO29288.1 - 8.7 4.2 9.9 9.5 4.1 6.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Hist_deacetyl PF00850.14 ETO29289.1 - 8.1e-56 189.5 0.2 1.1e-55 189.0 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain TUG-UBL1 PF11470.3 ETO29290.1 - 8.6e-06 25.5 0.0 2.4e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 GLUT4 regulating protein TUG PUA_2 PF14306.1 ETO29290.1 - 0.069 12.5 0.3 0.14 11.5 0.0 1.6 2 0 0 2 2 2 0 PUA-like domain VHS PF00790.14 ETO29291.1 - 1.7e-11 43.9 0.0 5.8e-06 25.9 0.0 2.1 2 0 0 2 2 2 2 VHS domain PP2C PF00481.16 ETO29292.1 - 4.8e-33 114.6 0.0 1.9e-31 109.3 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 ETO29292.1 - 0.071 12.5 0.1 0.55 9.5 0.1 2.0 1 1 0 1 1 1 0 Protein phosphatase 2C DUF2746 PF10874.3 ETO29293.1 - 0.034 14.3 0.1 0.12 12.5 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) Trichoplein PF13868.1 ETO29293.1 - 0.14 10.4 14.9 0.25 9.7 10.3 1.3 1 0 0 1 1 1 0 Tumour suppressor, Mitostatin MCPsignal PF00015.16 ETO29293.1 - 0.17 11.3 11.5 0.25 10.8 6.0 2.3 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain WD40 PF00400.27 ETO29294.1 - 5e-64 210.0 18.9 3.2e-12 45.8 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO29294.1 - 3e-06 25.6 2.9 0.73 7.8 0.0 4.6 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO29294.1 - 3.3e-05 22.3 0.6 0.0088 14.3 0.0 2.9 1 1 2 3 3 3 3 Cytochrome D1 heme domain DUF1652 PF07865.6 ETO29294.1 - 0.0011 18.4 0.0 0.4 10.3 0.0 3.2 2 1 1 3 3 3 2 Protein of unknown function (DUF1652) Resistin PF06954.6 ETO29294.1 - 0.14 12.4 2.7 57 4.0 0.1 4.9 2 2 3 6 6 6 0 Resistin PD40 PF07676.7 ETO29294.1 - 0.86 9.3 6.3 72 3.2 0.0 4.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat SpoIIIAC PF06686.6 ETO29295.1 - 3.4 7.5 7.0 1.8 8.4 2.8 1.9 1 1 1 2 2 2 0 Stage III sporulation protein AC/AD protein family LRR_4 PF12799.2 ETO29296.1 - 5e-10 38.7 17.2 1e-05 24.9 1.1 3.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO29296.1 - 1.6e-07 30.9 28.1 7.3e-06 25.6 6.8 3.0 1 1 2 3 3 3 3 Leucine rich repeat CcmB PF03379.8 ETO29296.1 - 0.017 14.3 0.3 0.021 14.0 0.2 1.2 1 0 0 1 1 1 0 CcmB protein LRR_1 PF00560.28 ETO29296.1 - 0.13 12.3 20.0 1 9.6 0.9 5.2 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.1 ETO29296.1 - 0.2 11.8 15.2 0.83 9.9 0.6 4.7 3 2 1 5 5 5 0 Leucine Rich repeat DUF3409 PF11889.3 ETO29297.1 - 1.8 8.3 9.2 35 4.1 6.4 2.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3409) ADIP PF11559.3 ETO29298.1 - 0.017 15.0 5.2 0.023 14.5 3.6 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding SLX9 PF15341.1 ETO29298.1 - 0.12 12.8 8.0 0.17 12.3 5.5 1.2 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 FNIP_N PF14636.1 ETO29298.1 - 0.21 12.0 8.6 0.37 11.2 6.0 1.3 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus RGS-like PF09128.6 ETO29298.1 - 0.32 10.4 4.4 0.5 9.8 3.0 1.3 1 1 0 1 1 1 0 Regulator of G protein signalling-like domain Rubella_Capsid PF05750.6 ETO29298.1 - 0.63 9.3 4.6 0.84 8.9 3.2 1.1 1 0 0 1 1 1 0 Rubella capsid protein AUX_IAA PF02309.11 ETO29298.1 - 1.2 8.7 6.7 1.6 8.4 4.7 1.1 1 0 0 1 1 1 0 AUX/IAA family DDHD PF02862.12 ETO29298.1 - 2.4 7.9 8.6 3.1 7.5 6.0 1.2 1 0 0 1 1 1 0 DDHD domain Apt1 PF10351.4 ETO29298.1 - 2.8 6.6 12.0 4 6.1 8.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Mito_fiss_reg PF05308.6 ETO29300.1 - 0.0016 17.8 3.0 0.0016 17.8 2.1 1.8 2 1 0 2 2 2 1 Mitochondrial fission regulator DUF4446 PF14584.1 ETO29300.1 - 0.02 14.7 0.4 0.052 13.3 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Med9 PF07544.8 ETO29300.1 - 0.032 13.9 1.3 0.08 12.6 0.9 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DivIC PF04977.10 ETO29300.1 - 0.43 10.1 5.1 0.15 11.5 1.5 1.7 2 0 0 2 2 2 0 Septum formation initiator OST-HTH PF12872.2 ETO29302.1 - 2.5e-06 27.2 0.5 0.00037 20.2 0.1 2.8 3 0 0 3 3 3 2 OST-HTH/LOTUS domain RRM_1 PF00076.17 ETO29302.1 - 0.016 14.8 0.0 0.06 12.9 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) cNMP_binding PF00027.24 ETO29305.1 - 7.4e-13 48.1 0.0 3.3e-06 26.8 0.0 3.0 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain APG6 PF04111.7 ETO29306.1 - 0.00037 19.6 50.6 0.00043 19.4 20.2 2.1 2 0 0 2 2 2 2 Autophagy protein Apg6 LMBR1 PF04791.11 ETO29306.1 - 0.0012 17.5 5.3 0.0012 17.5 3.7 2.1 1 1 1 2 2 1 1 LMBR1-like membrane protein DUF869 PF05911.6 ETO29306.1 - 0.0014 17.0 33.1 0.0016 16.7 23.0 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) DivIC PF04977.10 ETO29306.1 - 0.01 15.2 1.9 0.01 15.2 1.3 5.8 2 2 4 6 6 6 0 Septum formation initiator IncA PF04156.9 ETO29306.1 - 0.011 15.3 43.3 0.032 13.8 7.7 3.1 2 1 0 2 2 2 0 IncA protein SpaB_C PF14028.1 ETO29306.1 - 0.013 15.1 2.6 0.29 10.6 0.0 2.2 2 0 0 2 2 2 0 SpaB C-terminal domain Myosin_tail_1 PF01576.14 ETO29306.1 - 0.087 10.5 46.7 0.0033 15.2 17.3 2.1 2 0 0 2 2 2 0 Myosin tail CCDC144C PF14915.1 ETO29306.1 - 0.095 11.6 45.2 0.1 11.4 18.9 2.2 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region Fib_alpha PF08702.5 ETO29306.1 - 0.33 11.0 40.2 0.026 14.6 12.3 3.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family T2SF PF00482.18 ETO29306.1 - 0.34 10.8 6.9 2.8 7.8 0.2 3.1 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F UPF0564 PF10595.4 ETO29306.1 - 0.64 8.8 36.4 1 8.2 25.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 CALCOCO1 PF07888.6 ETO29306.1 - 0.67 8.1 38.4 0.04 12.2 16.7 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3584 PF12128.3 ETO29306.1 - 0.92 6.7 44.5 0.014 12.8 17.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Spc7 PF08317.6 ETO29306.1 - 2.2 6.8 42.2 0.054 12.1 2.5 3.1 2 1 1 3 3 3 0 Spc7 kinetochore protein Mnd1 PF03962.10 ETO29306.1 - 2.3 7.8 49.7 0.097 12.3 7.0 3.1 2 1 1 3 3 3 0 Mnd1 family AAA_13 PF13166.1 ETO29306.1 - 2.5 6.4 43.9 0.17 10.2 19.2 2.0 2 0 0 2 2 2 0 AAA domain TerB PF05099.8 ETO29306.1 - 3.3 7.4 8.6 0.56 9.9 1.4 2.7 2 1 0 2 2 2 0 Tellurite resistance protein TerB AAA_27 PF13514.1 ETO29306.1 - 3.5 5.1 38.7 0.38 8.3 14.1 2.2 2 0 0 2 2 2 0 AAA domain WXG100 PF06013.7 ETO29306.1 - 3.8 7.5 25.8 1 9.4 2.0 4.3 2 1 2 4 4 4 0 Proteins of 100 residues with WXG Filament PF00038.16 ETO29306.1 - 4.2 6.7 45.5 2.7 7.3 12.4 3.0 2 1 1 3 3 3 0 Intermediate filament protein DUF3708 PF12501.3 ETO29306.1 - 5.4 6.8 7.6 13 5.6 0.4 2.8 2 1 1 3 3 3 0 Phosphate ATP-binding cassette transporter TBPIP PF07106.8 ETO29306.1 - 8.4 5.9 44.1 1.5 8.3 6.7 3.8 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tropomyosin PF00261.15 ETO29306.1 - 8.4 5.4 39.6 4.8 6.2 13.5 2.2 2 0 0 2 2 2 0 Tropomyosin Fez1 PF06818.10 ETO29306.1 - 8.6 6.3 40.9 0.42 10.6 12.8 2.7 2 2 0 2 2 2 0 Fez1 Choline_transpo PF04515.7 ETO29307.1 - 9.2e-17 60.7 3.6 9.2e-17 60.7 2.5 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter DUF3611 PF12263.3 ETO29307.1 - 1.1 8.6 5.7 0.25 10.6 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) Choline_transpo PF04515.7 ETO29308.1 - 1e-48 165.7 22.0 2e-48 164.8 15.2 1.5 1 1 0 1 1 1 1 Plasma-membrane choline transporter Prothymosin PF03247.9 ETO29309.1 - 1.7 8.8 19.6 1.1 9.4 3.1 2.6 2 0 0 2 2 2 0 Prothymosin/parathymosin family DUF3439 PF11921.3 ETO29310.1 - 0.13 12.0 7.6 0.33 10.6 5.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Pex16 PF08610.5 ETO29310.1 - 0.34 9.8 4.3 0.5 9.3 3.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Spc97_Spc98 PF04130.8 ETO29311.1 - 4.4e-13 48.4 0.4 9.7e-13 47.2 0.3 1.4 1 1 0 1 1 1 1 Spc97 / Spc98 family DrsE_2 PF13686.1 ETO29311.1 - 0.029 14.1 0.7 0.048 13.4 0.5 1.3 1 0 0 1 1 1 0 DsrE/DsrF/DrsH-like family Myb_DNA-binding PF00249.26 ETO29312.1 - 0.07 13.1 0.2 0.33 11.0 0.1 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain Wbp11 PF09429.5 ETO29314.1 - 1.9e-10 40.5 12.5 1.9e-10 40.5 8.7 2.9 2 1 1 3 3 3 1 WW domain binding protein 11 Plasmodium_Vir PF05795.6 ETO29314.1 - 0.012 14.7 7.2 0.029 13.5 4.9 1.7 1 1 0 1 1 1 0 Plasmodium vivax Vir protein DUF3299 PF11736.3 ETO29314.1 - 3.4 7.5 10.3 1.7 8.5 4.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3299) Sec1 PF00995.18 ETO29315.1 - 5.4e-78 263.0 2.8 6.2e-78 262.8 2.0 1.0 1 0 0 1 1 1 1 Sec1 family HIT PF01230.18 ETO29316.1 - 9.5e-24 83.7 0.1 1.7e-23 83.0 0.1 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 ETO29316.1 - 1.3e-10 41.5 0.0 2.2e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 ETO29316.1 - 0.071 12.7 0.2 0.13 11.8 0.1 1.5 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 LepA_C PF06421.7 ETO29317.1 - 1.8e-36 124.3 4.0 3.1e-36 123.5 2.8 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 ETO29317.1 - 1.5e-12 47.1 0.0 3.7e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 ETO29317.1 - 4.4e-06 26.7 0.0 1.1e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 ETO29317.1 - 0.00088 19.0 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II adh_short PF00106.20 ETO29318.1 - 8e-18 64.9 0.0 2.2e-17 63.4 0.0 1.6 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETO29318.1 - 3.8e-08 33.2 0.0 5.8e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 KR domain SNARE_assoc PF09335.6 ETO29319.1 - 1.5e-07 31.6 0.5 3.5e-07 30.4 0.4 1.5 1 0 0 1 1 1 1 SNARE associated Golgi protein BDV_P10 PF06515.6 ETO29319.1 - 0.057 13.2 0.7 0.057 13.2 0.5 1.6 2 0 0 2 2 2 0 Borna disease virus P10 protein Menin PF05053.8 ETO29319.1 - 3.7 5.5 7.0 4.7 5.2 4.9 1.1 1 0 0 1 1 1 0 Menin DUF2431 PF10354.4 ETO29320.1 - 8.4e-18 64.8 4.3 1.3e-13 51.2 1.9 3.2 1 1 1 2 2 2 2 Domain of unknown function (DUF2431) FDX-ACB PF03147.9 ETO29320.1 - 0.00017 21.6 0.1 0.00089 19.3 0.0 2.3 2 1 0 2 2 2 1 Ferredoxin-fold anticodon binding domain F-box-like PF12937.2 ETO29320.1 - 0.00033 20.3 0.1 0.001 18.7 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETO29320.1 - 0.17 11.5 3.4 0.37 10.4 0.5 2.7 2 1 0 2 2 2 0 F-box domain Ofd1_CTDD PF10637.4 ETO29323.1 - 8.2e-09 34.9 0.6 8.2e-09 34.9 0.4 1.9 2 1 0 2 2 2 1 Oxoglutarate and iron-dependent oxygenase degradation C-term CENP-B_dimeris PF09026.5 ETO29323.1 - 0.5 10.6 11.3 0.085 13.1 4.7 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain SET PF00856.23 ETO29323.1 - 6.9 6.9 7.1 2.5 8.3 0.5 2.6 1 1 1 2 2 2 0 SET domain SDA1 PF05285.7 ETO29323.1 - 8.2 5.6 20.3 0.047 12.9 6.5 2.0 2 0 0 2 2 2 0 SDA1 RRM_5 PF13893.1 ETO29326.1 - 9.1e-09 35.0 0.0 2.9e-08 33.4 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO29326.1 - 8.5e-08 32.0 0.0 1.7e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO29326.1 - 3.8e-06 26.4 0.0 7.9e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RrnaAD PF00398.15 ETO29326.1 - 0.00058 18.9 0.0 0.00097 18.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Limkain-b1 PF11608.3 ETO29326.1 - 0.0012 18.5 0.6 0.0032 17.1 0.0 2.1 3 0 0 3 3 3 1 Limkain b1 Methyltransf_15 PF09445.5 ETO29326.1 - 0.014 14.9 0.0 0.038 13.5 0.0 1.7 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase SUKH-3 PF14433.1 ETO29327.1 - 0.015 15.0 0.1 0.03 14.1 0.0 1.6 2 0 0 2 2 2 0 SUKH-3 immunity protein DHDPS PF00701.17 ETO29327.1 - 0.049 12.2 0.0 0.099 11.2 0.0 1.5 2 0 0 2 2 2 0 Dihydrodipicolinate synthetase family TnpB_IS66 PF05717.8 ETO29328.1 - 0.031 13.7 0.1 0.36 10.2 0.0 2.2 2 0 0 2 2 2 0 IS66 Orf2 like protein D-ser_dehydrat PF14031.1 ETO29329.1 - 3.9e-08 33.3 0.0 7.7e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 ETO29329.1 - 6.1e-07 29.2 0.0 1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain KOW PF00467.24 ETO29330.1 - 0.00011 21.7 0.4 0.00011 21.7 0.3 2.9 2 0 0 2 2 2 1 KOW motif Daxx PF03344.10 ETO29330.1 - 0.071 11.5 22.8 0.085 11.3 15.8 1.1 1 0 0 1 1 1 0 Daxx Family FixO PF02433.10 ETO29330.1 - 0.093 12.0 5.7 0.019 14.3 1.8 1.5 2 0 0 2 2 2 0 Cytochrome C oxidase, mono-heme subunit/FixO Fumarate_red_C PF02300.12 ETO29331.1 - 0.12 12.3 0.8 0.53 10.1 0.1 2.2 1 1 1 2 2 2 0 Fumarate reductase subunit C zf-C2H2_4 PF13894.1 ETO29332.1 - 1.4e-06 28.2 28.2 0.0062 16.7 0.2 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 ETO29332.1 - 8.5e-06 25.8 22.4 0.00093 19.3 0.7 4.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETO29332.1 - 0.22 11.8 21.2 0.57 10.5 2.1 4.9 4 0 0 4 4 4 0 Zinc-finger double domain AT_hook PF02178.14 ETO29332.1 - 2.2 8.2 39.4 0.18 11.5 0.8 4.1 4 0 0 4 4 4 0 AT hook motif DUF2758 PF10957.3 ETO29333.1 - 0.31 10.8 3.3 3.1 7.6 0.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2758) Peptidase_S49_N PF08496.5 ETO29334.1 - 3.4 7.4 7.2 6.6 6.5 5.0 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal G-alpha PF00503.15 ETO29335.1 - 3.3e-60 203.8 3.0 1.2e-59 201.9 2.0 1.7 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO29335.1 - 1.3e-07 31.0 0.2 0.0082 15.4 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETO29335.1 - 0.0049 16.8 0.2 0.15 12.0 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 ETO29335.1 - 0.0068 16.1 0.5 0.0068 16.1 0.4 1.7 2 1 0 2 2 2 1 Archaeal ATPase Gtr1_RagA PF04670.7 ETO29335.1 - 0.01 14.9 0.1 4.1 6.4 0.0 2.5 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_14 PF13173.1 ETO29335.1 - 0.017 15.0 0.3 0.085 12.7 0.0 2.2 2 1 1 3 3 3 0 AAA domain Miro PF08477.8 ETO29335.1 - 0.02 15.3 0.1 0.69 10.4 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein GAD PF02938.9 ETO29335.1 - 0.078 13.1 0.0 0.23 11.6 0.0 1.9 1 0 0 1 1 1 0 GAD domain Mg_chelatase PF01078.16 ETO29335.1 - 0.084 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI CTP_transf_2 PF01467.21 ETO29336.1 - 2.6e-09 37.3 0.0 3.1e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase AICARFT_IMPCHas PF01808.13 ETO29337.1 - 0.032 13.3 0.0 0.042 12.9 0.0 1.1 1 0 0 1 1 1 0 AICARFT/IMPCHase bienzyme GH97_N PF14508.1 ETO29337.1 - 0.045 12.7 0.0 0.062 12.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 N-terminal Beach PF02138.13 ETO29338.1 - 4.9e-109 363.9 0.1 1.1e-108 362.8 0.1 1.6 1 0 0 1 1 1 1 Beige/BEACH domain FYVE PF01363.16 ETO29338.1 - 2e-16 59.6 14.8 4.2e-16 58.6 10.3 1.6 1 0 0 1 1 1 1 FYVE zinc finger WD40 PF00400.27 ETO29338.1 - 3.9e-15 55.0 16.3 2.5e-08 33.4 0.1 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat PH_BEACH PF14844.1 ETO29338.1 - 7.4e-13 48.2 1.8 7.4e-13 48.2 1.3 2.9 2 1 0 2 2 2 1 PH domain associated with Beige/BEACH HypA PF01155.14 ETO29338.1 - 0.24 11.0 4.3 0.57 9.8 3.0 1.6 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Pinin_SDK_memA PF04696.8 ETO29339.1 - 0.017 14.7 3.7 0.021 14.3 2.6 1.2 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Ribosomal_L13 PF00572.13 ETO29339.1 - 0.37 10.8 4.0 1.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Ribosomal protein L13 CENP-H PF05837.7 ETO29339.1 - 1.1 9.4 6.5 1.7 8.8 4.5 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Ribosomal_L13e PF01294.13 ETO29341.1 - 2.2e-20 72.8 0.5 2.2e-20 72.8 0.3 3.4 3 1 0 3 3 3 2 Ribosomal protein L13e Pkinase PF00069.20 ETO29345.1 - 1.5e-39 135.7 0.0 2.1e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO29345.1 - 7.8e-20 71.0 0.0 1e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO29345.1 - 0.00021 20.3 0.0 0.0067 15.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 ETO29345.1 - 0.032 13.9 0.1 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 ETO29345.1 - 0.066 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pribosyltran PF00156.22 ETO29346.1 - 5.1e-18 64.9 0.0 7.7e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 ETO29346.1 - 0.006 15.8 0.0 0.0093 15.1 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 ETO29346.1 - 0.036 13.3 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase B3_4 PF03483.12 ETO29347.1 - 1e-25 90.2 0.0 3e-25 88.6 0.0 1.8 2 0 0 2 2 2 1 B3/4 domain B5 PF03484.10 ETO29347.1 - 1.8e-16 59.7 0.0 8.9e-16 57.4 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetase B5 domain DUF1336 PF07059.7 ETO29348.1 - 4.2e-34 117.9 0.0 1.5e-24 86.7 0.0 2.2 1 1 0 2 2 2 2 Protein of unknown function (DUF1336) DUF464 PF04327.7 ETO29348.1 - 0.088 13.0 0.1 0.43 10.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF464) GTP_EFTU_D2 PF03144.20 ETO29350.1 - 0.0044 17.0 0.0 0.0081 16.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.12 ETO29350.1 - 0.014 15.5 0.1 0.052 13.7 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu C-terminal domain DUF4131 PF13567.1 ETO29350.1 - 1.2 8.5 10.1 2.2 7.6 0.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) SAM_2 PF07647.12 ETO29351.1 - 5.8e-06 26.0 0.0 9.3e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO29351.1 - 4.3e-05 23.6 0.0 6.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PX PF00787.19 ETO29351.1 - 0.00045 19.9 0.1 0.00079 19.2 0.1 1.4 1 0 0 1 1 1 1 PX domain Ste50p-SAM PF09235.5 ETO29351.1 - 0.0025 17.8 0.1 0.0076 16.2 0.0 1.8 1 1 1 2 2 2 1 Ste50p, sterile alpha motif Daxx PF03344.10 ETO29351.1 - 0.01 14.3 10.0 0.013 14.0 6.9 1.1 1 0 0 1 1 1 0 Daxx Family CENP-T PF15511.1 ETO29351.1 - 0.055 12.7 3.5 0.062 12.5 2.4 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 ETO29351.1 - 0.14 10.0 8.2 0.17 9.7 5.7 1.1 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.8 ETO29351.1 - 0.31 9.7 7.5 0.42 9.3 5.2 1.1 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.9 ETO29351.1 - 0.33 8.9 2.7 0.39 8.6 1.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 ETO29351.1 - 0.39 9.4 9.8 0.53 8.9 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 ETO29351.1 - 0.45 10.0 9.0 0.79 9.2 6.3 1.4 1 0 0 1 1 1 0 Nucleoplasmin TEX19 PF15553.1 ETO29351.1 - 0.72 9.7 5.1 1.1 9.0 3.6 1.3 1 0 0 1 1 1 0 Testis-expressed protein 19 Sigma70_ner PF04546.8 ETO29351.1 - 0.86 9.1 7.7 1.3 8.5 5.3 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region TRAP_alpha PF03896.11 ETO29351.1 - 1.6 7.6 5.0 2.8 6.8 3.5 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DARPP-32 PF05395.7 ETO29351.1 - 1.7 8.8 6.4 2.5 8.2 4.4 1.3 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 GRP PF07172.6 ETO29351.1 - 4.4 7.8 12.8 8.2 6.9 8.9 1.4 1 0 0 1 1 1 0 Glycine rich protein family CobT PF06213.7 ETO29351.1 - 4.6 6.2 13.7 5.9 5.9 9.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pkinase PF00069.20 ETO29352.1 - 1.8e-11 43.6 0.0 8.3e-11 41.5 0.0 3.2 4 1 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO29352.1 - 5.5e-10 38.7 0.2 5.5e-10 38.7 0.2 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase_Tyr PF07714.12 ETO29353.1 - 2.3e-14 53.1 0.1 2.5e-12 46.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 ETO29353.1 - 4.1e-08 32.6 0.0 4.8e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Rieske PF00355.21 ETO29354.1 - 2.4e-08 33.4 0.0 7.8e-08 31.7 0.0 1.8 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 ETO29354.1 - 2.9e-07 30.1 0.0 5.6e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 Rieske-like [2Fe-2S] domain LRR_4 PF12799.2 ETO29355.1 - 0.0023 17.4 0.8 0.005 16.4 0.6 1.6 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO29355.1 - 0.041 13.6 1.0 0.1 12.3 0.3 1.9 2 0 0 2 2 2 0 Leucine rich repeat HATPase_c PF02518.21 ETO29357.1 - 0.091 12.4 0.1 0.27 10.9 0.1 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FKBP_C PF00254.23 ETO29358.1 - 6.2e-27 93.4 0.0 9.9e-27 92.8 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase MORN PF02493.15 ETO29358.1 - 0.078 12.7 1.0 0.2 11.4 0.7 1.8 1 0 0 1 1 1 0 MORN repeat zf-CCCH PF00642.19 ETO29359.1 - 0.0011 18.5 0.4 0.0022 17.6 0.3 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SNase PF00565.12 ETO29361.1 - 9.3e-28 96.6 36.0 2.4e-10 40.6 1.5 8.0 5 4 1 6 6 6 5 Staphylococcal nuclease homologue TUDOR PF00567.19 ETO29361.1 - 4.8e-12 45.7 0.0 4.2e-11 42.7 0.0 2.4 2 0 0 2 2 2 1 Tudor domain DUF972 PF06156.8 ETO29362.1 - 0.16 12.2 1.7 0.43 10.9 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) FAM176 PF14851.1 ETO29362.1 - 2.5 7.7 5.5 0.56 9.8 1.0 2.0 2 0 0 2 2 2 0 FAM176 family WD40 PF00400.27 ETO29364.1 - 1.1e-51 170.9 11.4 1.1e-11 44.1 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO29364.1 - 6e-12 45.6 0.1 0.0015 18.2 0.0 3.5 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO29364.1 - 1.5e-06 27.7 1.2 9.1 6.0 0.0 5.7 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO29364.1 - 9.4e-06 24.0 1.1 1.5 6.8 0.0 3.9 2 2 2 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO29364.1 - 7.2e-05 21.2 0.0 0.0097 14.2 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain DUF1258 PF06869.7 ETO29364.1 - 0.00029 20.0 0.2 0.44 9.5 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1258) Nucleoporin_N PF08801.6 ETO29364.1 - 0.00082 18.2 3.9 3.2 6.3 0.0 4.2 2 2 2 4 4 4 2 Nup133 N terminal like Resistin PF06954.6 ETO29364.1 - 0.0026 18.0 0.7 2.1 8.6 0.0 4.2 3 1 2 5 5 5 1 Resistin Hira PF07569.6 ETO29364.1 - 0.019 14.1 0.4 13 4.8 0.0 3.2 3 0 0 3 3 3 0 TUP1-like enhancer of split PQQ_2 PF13360.1 ETO29364.1 - 0.029 13.8 0.0 0.079 12.4 0.0 1.9 1 1 0 1 1 1 0 PQQ-like domain PQQ PF01011.16 ETO29364.1 - 0.046 13.2 0.0 4.2 7.0 0.0 2.5 2 0 0 2 2 2 0 PQQ enzyme repeat DUF4131 PF13567.1 ETO29364.1 - 0.16 11.3 4.0 0.24 10.7 2.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) WD40 PF00400.27 ETO29365.1 - 2.2e-61 201.7 28.2 4.7e-11 42.1 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO29365.1 - 9.7e-10 37.1 5.8 7.7e-05 21.0 0.1 4.7 1 1 2 4 4 4 4 Nucleoporin Nup120/160 DUF851 PF05867.6 ETO29365.1 - 0.013 14.7 0.1 63 2.6 0.0 3.8 2 1 2 4 4 4 0 Protein of unknown function (DUF851) APOBEC_C PF05240.9 ETO29367.1 - 0.081 12.3 0.2 0.21 10.9 0.1 1.7 1 0 0 1 1 1 0 APOBEC-like C-terminal domain TryThrA_C PF12319.3 ETO29368.1 - 0.03 13.4 0.4 0.038 13.1 0.3 1.1 1 0 0 1 1 1 0 Tryptophan-Threonine-rich plasmodium antigen C terminal PAP_assoc PF03828.14 ETO29369.1 - 1.6e-09 37.5 0.0 5.2e-09 35.9 0.0 2.0 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 ETO29369.1 - 0.00032 20.9 0.0 0.00089 19.5 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Zip PF02535.17 ETO29369.1 - 0.04 12.9 3.8 0.071 12.1 2.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter tRNA_NucTransf2 PF09249.6 ETO29369.1 - 0.08 12.8 0.0 0.24 11.2 0.0 1.8 1 0 0 1 1 1 0 tRNA nucleotidyltransferase, second domain AgrB PF04647.10 ETO29371.1 - 0.00094 18.2 2.0 0.00094 18.2 1.4 2.2 1 1 1 2 2 2 1 Accessory gene regulator B Tmemb_18A PF09771.4 ETO29371.1 - 0.015 15.2 1.9 0.015 15.2 1.3 2.2 1 1 1 2 2 2 0 Transmembrane protein 188 ETRAMP PF09716.5 ETO29371.1 - 0.35 10.8 4.9 15 5.6 0.0 3.5 2 2 1 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) PgaD PF13994.1 ETO29371.1 - 0.61 9.5 0.1 0.61 9.5 0.0 3.1 2 1 1 3 3 3 0 PgaD-like protein DUF4381 PF14316.1 ETO29371.1 - 1.1 9.3 3.9 24 5.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF843 PF05814.6 ETO29371.1 - 1.5 8.6 0.0 1.5 8.6 0.0 3.3 2 1 2 4 4 4 0 Baculovirus protein of unknown function (DUF843) RCR PF12273.3 ETO29371.1 - 1.6 9.2 7.2 12 6.4 0.5 2.8 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red DUF4234 PF14018.1 ETO29371.1 - 1.9 8.3 21.9 27 4.5 15.1 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4234) SAM_2 PF07647.12 ETO29372.1 - 0.031 14.1 0.1 0.073 12.9 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO29372.1 - 0.043 14.0 0.0 0.089 12.9 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Mucin PF01456.12 ETO29372.1 - 0.16 11.7 23.6 6.6 6.5 0.0 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF515 PF04415.7 ETO29372.1 - 0.21 9.7 10.3 0.41 8.8 7.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SSP160 PF06933.6 ETO29372.1 - 1.2 7.0 16.0 2 6.2 11.1 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Toxin_52 PF15605.1 ETO29372.1 - 2.8 7.8 7.6 3.5 7.5 0.5 3.6 3 1 1 4 4 4 0 Putative toxin 52 AIP3 PF03915.8 ETO29372.1 - 4.8 5.9 12.8 1.2 7.9 5.6 2.0 2 0 0 2 2 2 0 Actin interacting protein 3 DAGK_cat PF00781.19 ETO29374.1 - 2.6e-05 23.6 1.9 4.6e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.16 ETO29374.1 - 0.16 10.7 1.1 0.26 10.0 0.0 1.8 2 0 0 2 2 2 0 ATP-NAD kinase FHIPEP PF00771.15 ETO29374.1 - 2.4 6.3 9.7 3.5 5.8 6.7 1.2 1 0 0 1 1 1 0 FHIPEP family Noggin PF05806.7 ETO29375.1 - 0.14 11.4 0.1 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 Noggin DUF4644 PF15486.1 ETO29376.1 - 0.085 12.8 0.5 0.26 11.2 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4644) CDC45 PF02724.9 ETO29377.1 - 0.0016 16.5 4.3 0.0016 16.5 2.9 1.7 2 0 0 2 2 2 1 CDC45-like protein DAGAT PF03982.8 ETO29377.1 - 0.1 11.2 0.1 0.16 10.6 0.1 1.2 1 0 0 1 1 1 0 Diacylglycerol acyltransferase DUF4205 PF13898.1 ETO29380.1 - 3.6e-19 68.6 0.1 8e-16 57.6 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4205) zf-RanBP PF00641.13 ETO29380.1 - 1.1e-05 24.3 2.4 2e-05 23.6 1.7 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.10 ETO29380.1 - 0.33 10.5 6.4 0.054 13.0 1.1 2.2 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger JmjC PF02373.17 ETO29381.1 - 1.6 8.9 5.1 2.6 8.3 0.4 2.9 2 2 1 3 3 3 0 JmjC domain, hydroxylase Herpes_DNAp_acc PF04929.7 ETO29381.1 - 6.3 5.6 15.2 13 4.6 10.6 1.5 1 0 0 1 1 1 0 Herpes DNA replication accessory factor FAM177 PF14774.1 ETO29382.1 - 7e-13 48.5 7.9 7e-13 48.5 5.5 2.7 2 1 0 2 2 2 1 FAM177 family DUF1501 PF07394.7 ETO29382.1 - 0.028 13.2 3.2 0.016 14.0 0.8 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1501) GET2 PF08690.5 ETO29382.1 - 0.65 9.1 11.3 0.29 10.3 2.4 2.1 2 0 0 2 2 2 0 GET complex subunit GET2 DUF2422 PF10337.4 ETO29382.1 - 1 8.1 4.1 1.5 7.5 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) VHP PF02209.14 ETO29382.1 - 9.6 5.9 8.0 1.7e+02 1.9 5.6 2.3 1 1 0 1 1 1 0 Villin headpiece domain DNA_processg_A PF02481.10 ETO29385.1 - 0.069 12.0 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 DNA recombination-mediator protein A zf-DHHC PF01529.15 ETO29385.1 - 0.18 11.1 13.2 0.56 9.5 0.0 3.4 3 1 0 3 3 3 0 DHHC palmitoyltransferase MatE PF01554.13 ETO29386.1 - 1.9e-43 147.8 39.0 2.7e-26 92.1 5.3 2.7 3 0 0 3 3 3 2 MatE TLP-20 PF06088.6 ETO29386.1 - 0.0082 15.8 6.6 0.015 14.9 4.6 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Erf4 PF10256.4 ETO29386.1 - 0.025 14.4 0.3 0.025 14.4 0.2 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family RNA_pol_Rpb1_1 PF04997.7 ETO29386.1 - 0.057 12.6 3.5 0.093 11.9 2.4 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 PDR_CDR PF06422.7 ETO29386.1 - 0.06 13.0 0.3 0.47 10.1 0.1 2.5 2 0 0 2 2 2 0 CDR ABC transporter Sporozoite_P67 PF05642.6 ETO29386.1 - 0.36 8.6 2.4 0.54 8.0 1.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CENP-B_dimeris PF09026.5 ETO29386.1 - 0.62 10.3 11.1 1.2 9.3 7.7 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2457 PF10446.4 ETO29386.1 - 5.4 5.6 16.1 7.5 5.1 11.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sulfotransfer_3 PF13469.1 ETO29387.1 - 0.0034 18.3 0.2 0.016 16.1 0.0 2.0 2 1 0 2 2 2 1 Sulfotransferase family 3Beta_HSD PF01073.14 ETO29388.1 - 1.1e-12 47.2 0.1 1.5e-12 46.8 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 ETO29388.1 - 2.5e-05 23.8 0.0 3.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ETO29388.1 - 0.0024 16.8 0.0 0.0034 16.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 ETO29388.1 - 0.0048 15.8 0.0 0.0062 15.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Cas_APE2256 PF09651.5 ETO29389.1 - 0.073 12.7 1.4 0.25 11.0 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_APE2256) Lipocalin_4 PF13648.1 ETO29389.1 - 0.077 13.6 0.5 0.077 13.6 0.3 2.6 2 1 0 2 2 2 0 Lipocalin-like domain HCaRG PF07258.9 ETO29390.1 - 3.6e-21 75.4 2.9 1.1e-18 67.4 0.0 2.1 2 0 0 2 2 2 2 HCaRG protein zf-C3HC4_3 PF13920.1 ETO29391.1 - 1.7e-12 46.7 8.8 1.7e-12 46.7 6.1 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO29391.1 - 1.2e-06 28.3 12.2 3e-06 27.1 8.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 ETO29391.1 - 1.7e-05 24.2 5.5 3.9e-05 23.0 3.8 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.1 ETO29391.1 - 0.00096 18.9 11.5 0.0021 17.8 8.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 ETO29391.1 - 0.0019 17.9 10.2 0.0043 16.7 7.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain DUF4193 PF13834.1 ETO29391.1 - 0.089 12.9 4.4 0.27 11.4 3.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4193) zf-C3HC4 PF00097.20 ETO29391.1 - 0.37 10.5 11.6 0.92 9.2 8.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1644 PF07800.7 ETO29391.1 - 1.3 8.8 10.4 2.5e+02 1.4 7.2 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) G-alpha PF00503.15 ETO29392.1 - 6.7e-16 57.9 11.7 1.2e-15 57.1 8.1 1.5 1 1 0 1 1 1 1 G-protein alpha subunit AA_permease_N PF08403.5 ETO29392.1 - 0.0017 17.6 0.0 0.0036 16.5 0.0 1.5 1 0 0 1 1 1 1 Amino acid permease N-terminal Tubulin_C PF03953.12 ETO29393.1 - 2.6e-29 101.8 0.0 3.3e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 ETO29394.1 - 2.3e-60 204.0 0.1 1.4e-36 126.3 0.1 2.1 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.4 ETO29394.1 - 0.0086 16.1 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain PCI PF01399.22 ETO29395.1 - 1.5e-13 50.9 0.4 1.5e-13 50.9 0.3 2.2 2 1 0 2 2 2 1 PCI domain Sel1 PF08238.7 ETO29395.1 - 0.046 14.3 0.1 0.41 11.3 0.0 2.6 2 0 0 2 2 2 0 Sel1 repeat Pkinase PF00069.20 ETO29397.1 - 7.1e-55 185.9 0.2 5.3e-54 183.0 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO29397.1 - 3.7e-20 72.0 0.0 1.1e-19 70.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO29397.1 - 0.00053 19.0 0.0 0.00064 18.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 ETO29397.1 - 0.0019 17.5 0.1 0.011 15.1 0.0 1.9 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL APH PF01636.18 ETO29397.1 - 0.014 15.1 0.1 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 ETO29397.1 - 0.043 12.8 0.0 0.065 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_1 PF00036.27 ETO29398.1 - 9.1e-32 105.9 7.0 5.8e-08 31.4 0.1 5.0 5 0 0 5 5 5 4 EF hand EF-hand_5 PF13202.1 ETO29398.1 - 1.5e-30 103.1 4.6 9.4e-07 27.9 0.0 5.1 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 ETO29398.1 - 1.8e-27 95.2 2.2 3.6e-13 49.4 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO29398.1 - 5.5e-24 81.8 5.6 4.5e-05 22.9 0.0 5.1 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 ETO29398.1 - 7.1e-20 70.3 13.6 4.6e-08 32.5 0.2 5.0 3 1 2 5 5 5 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 ETO29398.1 - 6.1e-08 32.6 0.1 0.0071 16.3 0.1 2.4 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 ETO29398.1 - 2.6e-06 27.1 2.2 0.05 13.3 0.4 2.9 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 ETO29398.1 - 0.015 15.1 0.2 2.2 8.2 0.0 2.8 2 1 0 2 2 2 0 EF-hand domain CEP19 PF14933.1 ETO29398.1 - 0.033 14.4 0.0 0.044 14.0 0.0 1.2 1 0 0 1 1 1 0 CEP19-like protein TerB PF05099.8 ETO29398.1 - 0.081 12.6 0.2 1.9 8.2 0.0 2.1 1 1 1 2 2 2 0 Tellurite resistance protein TerB EF-hand_10 PF14788.1 ETO29398.1 - 0.12 12.0 2.9 6.5 6.5 0.3 3.1 2 1 2 4 4 4 0 EF hand ArfGap PF01412.13 ETO29399.1 - 8.3e-35 119.1 5.2 6.5e-23 80.7 0.3 2.5 1 1 1 2 2 2 2 Putative GTPase activating protein for Arf PH PF00169.24 ETO29400.1 - 1.7e-10 41.0 0.0 4e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 PH domain Toxin-deaminase PF14424.1 ETO29400.1 - 0.0085 16.0 0.5 0.18 11.8 0.0 2.6 3 0 0 3 3 3 1 The BURPS668_1122 family of deaminases PH_11 PF15413.1 ETO29400.1 - 0.028 14.6 0.0 0.072 13.3 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain FYVE PF01363.16 ETO29400.1 - 0.034 14.0 12.9 0.78 9.6 8.9 2.3 1 1 0 1 1 1 0 FYVE zinc finger Evr1_Alr PF04777.8 ETO29400.1 - 0.037 13.9 3.5 0.038 13.8 1.4 1.8 1 1 0 1 1 1 0 Erv1 / Alr family ROS_MUCR PF05443.6 ETO29400.1 - 0.043 13.5 0.0 0.073 12.8 0.0 1.2 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein Sec7 PF01369.15 ETO29401.1 - 5.5e-32 110.9 0.0 9.6e-32 110.1 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain LANC_like PF05147.8 ETO29404.1 - 0.0007 18.2 0.0 0.00086 17.9 0.0 1.0 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein LANC_like PF05147.8 ETO29405.1 - 1.8e-05 23.5 0.0 1.9e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein DUF3510 PF12022.3 ETO29406.1 - 3.5e-09 36.8 1.3 1.1e-08 35.2 0.9 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) RNA_pol PF00940.14 ETO29407.1 - 0.0028 16.1 0.1 0.0032 16.0 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase MSP7_C PF12948.2 ETO29407.1 - 0.33 11.1 13.2 1.6 8.9 5.5 2.6 2 0 0 2 2 2 0 MSP7-like protein C-terminal domain Cytidylate_kin2 PF13189.1 ETO29408.1 - 0.038 13.8 0.4 0.038 13.8 0.3 2.6 4 0 0 4 4 4 0 Cytidylate kinase-like family Asp_Glu_race_2 PF14669.1 ETO29408.1 - 0.044 13.0 0.2 0.47 9.7 0.0 2.1 2 0 0 2 2 2 0 Putative aspartate racemase DUF4490 PF14892.1 ETO29408.1 - 0.83 9.3 4.4 4.6 6.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4490) WD40 PF00400.27 ETO29409.1 - 7.2e-85 276.1 18.7 4.6e-13 48.4 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO29409.1 - 5.7e-11 42.4 0.2 0.00033 20.4 0.0 3.7 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO29409.1 - 2.4e-06 27.0 1.7 12 5.7 0.0 5.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO29409.1 - 2.3e-05 23.3 4.2 0.41 9.3 0.1 4.3 1 1 4 5 5 5 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO29409.1 - 0.00079 17.8 0.3 0.25 9.5 0.0 3.1 2 1 0 3 3 3 1 Cytochrome D1 heme domain DUF4221 PF13970.1 ETO29409.1 - 0.0015 17.8 0.2 0.24 10.7 0.0 3.6 2 2 2 4 4 4 1 Domain of unknown function (DUF4221) Resistin PF06954.6 ETO29409.1 - 0.0016 18.6 0.3 28 5.0 0.0 4.2 2 2 1 4 4 4 0 Resistin PQQ_2 PF13360.1 ETO29409.1 - 0.0019 17.7 1.0 0.38 10.1 0.0 3.0 1 1 3 4 4 4 2 PQQ-like domain DUF1258 PF06869.7 ETO29409.1 - 0.0026 16.8 0.4 2.9 6.9 0.0 3.0 2 2 2 4 4 4 2 Protein of unknown function (DUF1258) DUF3601 PF12208.3 ETO29409.1 - 0.0046 16.8 0.0 12 5.9 0.0 4.5 4 1 2 6 6 6 0 Domain of unknown function (DUF3601) Coatomer_WDAD PF04053.9 ETO29409.1 - 0.005 15.6 0.2 0.33 9.6 0.0 2.7 1 1 1 3 3 3 1 Coatomer WD associated region SoxZ PF08770.6 ETO29409.1 - 0.0091 15.4 0.0 43 3.6 0.0 4.1 3 1 1 4 4 4 0 Sulphur oxidation protein SoxZ Me-amine-dh_H PF06433.6 ETO29409.1 - 0.015 13.9 0.0 0.53 8.8 0.0 2.6 2 1 0 3 3 3 0 Methylamine dehydrogenase heavy chain (MADH) DUF3732 PF12532.3 ETO29409.1 - 0.016 14.7 0.0 0.85 9.1 0.0 3.5 4 1 1 5 5 5 0 Protein of unknown function (DUF3732) Proteasome_A_N PF10584.4 ETO29409.1 - 0.048 12.9 0.2 43 3.5 0.0 4.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Flu_M1 PF00598.14 ETO29410.1 - 0.021 14.2 0.1 0.055 12.8 0.1 1.7 1 0 0 1 1 1 0 Influenza Matrix protein (M1) DUF2458 PF10454.4 ETO29410.1 - 0.024 14.5 1.7 0.024 14.5 1.1 2.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2458) Coatomer_E PF04733.9 ETO29411.1 - 5.3e-20 71.7 1.9 7.2e-20 71.3 1.3 1.2 1 0 0 1 1 1 1 Coatomer epsilon subunit Coatomer_E PF04733.9 ETO29412.1 - 1.1e-31 110.1 4.0 1.2e-31 109.9 2.8 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 ETO29412.1 - 5.5e-06 26.6 1.0 0.00082 19.6 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO29412.1 - 0.00012 22.1 0.9 0.00027 21.0 0.3 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 ETO29412.1 - 0.0049 16.7 0.4 0.031 14.1 0.1 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO29412.1 - 0.017 15.7 0.5 19 6.2 0.0 3.6 3 2 2 5 5 5 0 Tetratricopeptide repeat DUF3328 PF11807.3 ETO29412.1 - 0.06 13.0 0.0 0.54 9.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) PPR PF01535.15 ETO29412.1 - 0.3 11.1 1.8 20 5.4 0.0 3.6 4 0 0 4 4 4 0 PPR repeat PPR_3 PF13812.1 ETO29412.1 - 0.93 9.9 4.6 12 6.4 0.2 3.6 4 1 0 4 4 4 0 Pentatricopeptide repeat domain UPF0542 PF15086.1 ETO29413.1 - 0.034 13.8 0.2 0.034 13.8 0.2 3.2 3 1 0 3 3 3 0 Uncharacterised protein family UPF0542 PBP_sp32 PF07222.7 ETO29413.1 - 0.63 9.1 9.6 0.08 12.1 2.0 2.1 2 0 0 2 2 2 0 Proacrosin binding protein sp32 DUF2203 PF09969.4 ETO29413.1 - 1.8 8.7 6.0 2.1 8.6 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) OAD_gamma PF04277.8 ETO29413.1 - 1.9 8.8 9.6 3.1 8.2 0.1 3.2 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain GFA PF04828.9 ETO29414.1 - 7.6e-09 35.4 5.8 1.6e-08 34.3 4.0 1.6 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF912 PF06024.7 ETO29414.1 - 0.14 12.2 0.5 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PDR_CDR PF06422.7 ETO29414.1 - 5.3 6.7 8.0 17 5.1 0.0 2.8 3 1 1 4 4 4 0 CDR ABC transporter Peptidase_M16_C PF05193.16 ETO29415.1 - 1.1e-09 38.1 0.0 1.4e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16_C PF05193.16 ETO29416.1 - 6.5e-13 48.7 0.0 1.4e-12 47.7 0.0 1.5 2 0 0 2 2 2 1 Peptidase M16 inactive domain NinB PF05772.7 ETO29416.1 - 0.00096 18.7 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 NinB protein RhoGAP PF00620.22 ETO29417.1 - 1.2e-12 47.7 0.0 1.8e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain PBD PF00786.23 ETO29417.1 - 0.021 15.2 0.0 0.12 12.7 0.0 2.3 1 1 1 2 2 2 0 P21-Rho-binding domain Tcp10_C PF07202.8 ETO29420.1 - 1e-25 90.3 4.1 3.2e-19 69.1 1.7 2.0 1 1 1 2 2 2 2 T-complex protein 10 C-terminus SeqA PF03925.8 ETO29420.1 - 0.01 15.5 0.1 0.012 15.3 0.0 1.2 1 0 0 1 1 1 0 SeqA protein Tetraspannin PF00335.15 ETO29421.1 - 0.53 9.5 7.6 2.8 7.1 5.3 2.1 1 1 0 1 1 1 0 Tetraspanin family YL1 PF05764.8 ETO29423.1 - 0.014 15.0 9.5 0.016 14.8 6.6 1.1 1 0 0 1 1 1 0 YL1 nuclear protein ECSIT PF06239.6 ETO29423.1 - 0.057 12.2 5.8 0.067 12.0 4.0 1.1 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway Host_attach PF10116.4 ETO29423.1 - 0.13 12.4 1.0 0.18 12.0 0.7 1.2 1 0 0 1 1 1 0 Protein required for attachment to host cells RP-C_C PF11800.3 ETO29423.1 - 0.49 10.0 3.0 0.55 9.9 2.1 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region SPATIAL PF15256.1 ETO29424.1 - 8.2 6.4 15.4 0.81 9.7 5.8 2.2 2 0 0 2 2 2 0 SPATIAL DUF3332 PF11810.3 ETO29424.1 - 9.5 5.8 15.3 0.59 9.7 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3332) SET PF00856.23 ETO29426.1 - 0.00017 21.9 0.0 0.00032 21.0 0.0 1.4 1 0 0 1 1 1 1 SET domain MRP-S23 PF10484.4 ETO29427.1 - 0.11 12.4 1.1 1.9 8.3 0.0 2.5 2 1 1 3 3 3 0 Mitochondrial ribosomal protein S23 YsaB PF13983.1 ETO29427.1 - 0.19 11.8 1.8 2.2 8.4 0.0 2.9 3 0 0 3 3 3 0 YsaB-like lipoprotein Pre-SET PF05033.11 ETO29427.1 - 2.3 8.5 10.3 1.7 8.9 5.5 1.9 2 0 0 2 2 2 0 Pre-SET motif DUF2749 PF10907.3 ETO29428.1 - 0.48 10.3 2.0 14 5.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2749) Pox_C7_F8A PF03287.9 ETO29430.1 - 0.097 12.3 0.4 0.19 11.4 0.1 1.5 1 1 0 1 1 1 0 Poxvirus C7/F8A protein HECT PF00632.20 ETO29431.1 - 6.6e-37 127.3 0.0 8.1e-37 127.0 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) GED PF02212.13 ETO29431.1 - 0.002 17.9 0.0 0.0048 16.7 0.0 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain TPR_11 PF13414.1 ETO29432.1 - 1.9e-16 59.4 28.1 1.5e-06 27.7 2.6 4.9 2 1 3 5 5 5 5 TPR repeat TPR_2 PF07719.12 ETO29432.1 - 1.4e-12 46.5 16.3 0.016 15.0 0.2 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETO29432.1 - 5.4e-12 44.9 24.1 0.00072 19.5 0.0 8.0 6 1 2 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.1 ETO29432.1 - 1.7e-10 40.7 29.6 1.2e-06 28.3 3.2 5.1 2 2 4 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO29432.1 - 2e-09 36.6 23.3 0.037 13.6 0.0 6.2 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO29432.1 - 4e-06 26.9 2.5 5.8 7.8 0.1 5.4 3 3 2 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO29432.1 - 8.7e-06 26.2 9.2 0.038 14.6 0.1 4.2 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO29432.1 - 4.2e-05 23.0 13.3 0.00056 19.5 0.1 4.7 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO29432.1 - 8.3e-05 22.8 5.0 1.3 9.4 0.0 4.3 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO29432.1 - 0.00044 19.8 17.6 0.76 9.7 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETO29432.1 - 0.085 12.7 2.9 2.6 7.9 0.1 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 ETO29432.1 - 0.52 10.3 0.1 0.52 10.3 0.1 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF3856 PF12968.2 ETO29432.1 - 1 9.1 4.8 1.6 8.5 0.4 3.1 3 1 0 3 3 2 0 Domain of Unknown Function (DUF3856) PRNT PF15174.1 ETO29433.1 - 0.062 12.9 0.1 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 Prion-related protein testis-specific Pkinase PF00069.20 ETO29436.1 - 0.00054 19.1 0.3 0.00092 18.4 0.2 1.4 1 0 0 1 1 1 1 Protein kinase domain DUF1126 PF06565.7 ETO29438.1 - 2.5e-18 65.2 0.3 4.9e-10 38.7 0.0 2.9 3 0 0 3 3 3 2 Repeat of unknown function (DUF1126) EF-hand_8 PF13833.1 ETO29438.1 - 8.4e-06 25.3 0.1 2.2e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO29438.1 - 2e-05 23.5 0.1 5.2e-05 22.2 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 ETO29438.1 - 8.6e-05 22.1 0.1 0.00031 20.3 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 ETO29438.1 - 0.0017 18.4 0.1 0.0063 16.6 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 ETO29438.1 - 0.0025 17.0 0.1 0.0068 15.7 0.1 1.7 1 0 0 1 1 1 1 EF hand VHS PF00790.14 ETO29439.1 - 0.00015 21.3 0.4 0.00061 19.4 0.1 2.2 2 1 0 2 2 2 1 VHS domain ACT PF01842.20 ETO29439.1 - 0.031 13.7 0.0 0.078 12.4 0.0 1.7 1 0 0 1 1 1 0 ACT domain RhoGEF PF00621.15 ETO29444.1 - 7.7e-16 58.4 4.5 7.7e-16 58.4 3.1 2.1 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.24 ETO29444.1 - 0.0013 18.9 15.1 0.046 13.9 5.3 3.6 2 1 1 3 3 3 2 PH domain IPT PF01745.11 ETO29444.1 - 0.016 14.3 0.2 0.024 13.8 0.1 1.3 1 0 0 1 1 1 0 Isopentenyl transferase PH_11 PF15413.1 ETO29444.1 - 0.074 13.2 6.5 0.13 12.5 1.9 3.0 1 1 1 2 2 2 0 Pleckstrin homology domain Secretin_N_2 PF07655.8 ETO29444.1 - 0.24 11.8 11.8 0.081 13.3 6.2 1.7 2 0 0 2 2 2 0 Secretin N-terminal domain DUF912 PF06024.7 ETO29444.1 - 3.3 7.8 9.5 1.1 9.3 4.2 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) p450 PF00067.17 ETO29445.1 - 3.2e-53 180.8 0.7 3.9e-53 180.6 0.5 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_4 PF02390.12 ETO29445.1 - 0.12 11.3 0.0 0.66 8.9 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase EMP70 PF02990.11 ETO29447.1 - 5.8e-78 262.6 31.2 6.9e-78 262.3 21.6 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 DUF2636 PF11120.3 ETO29447.1 - 0.023 14.1 3.9 0.38 10.2 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2636) EMP70 PF02990.11 ETO29448.1 - 1.6e-32 112.6 0.8 1.9e-32 112.4 0.5 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 P12 PF12669.2 ETO29448.1 - 0.21 11.7 4.6 2.2 8.5 0.4 2.4 2 0 0 2 2 2 0 Virus attachment protein p12 family Viral_Beta_CD PF04530.7 ETO29448.1 - 0.24 11.5 1.4 0.77 9.9 0.0 2.3 1 1 2 3 3 3 0 Viral Beta C/D like family DUF3816 PF12822.2 ETO29448.1 - 0.26 11.1 2.6 1.2 8.9 1.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) TF_AP-2 PF03299.9 ETO29449.1 - 0.063 12.8 4.0 0.098 12.1 2.8 1.4 1 1 0 1 1 1 0 Transcription factor AP-2 Lip_prot_lig_C PF10437.4 ETO29449.1 - 0.11 12.1 0.4 0.17 11.5 0.3 1.2 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus DUF972 PF06156.8 ETO29449.1 - 0.68 10.3 7.7 0.85 10.0 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF4572 PF15139.1 ETO29449.1 - 0.86 9.4 6.4 0.99 9.2 4.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4572) CALCOCO1 PF07888.6 ETO29449.1 - 1.1 7.5 7.5 1.1 7.4 5.2 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Med4 PF10018.4 ETO29449.1 - 1.3 8.4 8.1 1.7 7.9 5.6 1.3 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 CART PF06373.6 ETO29449.1 - 2.9 7.8 4.4 1.7 8.6 0.3 2.0 1 1 1 2 2 2 0 Cocaine and amphetamine regulated transcript protein (CART) YlqD PF11068.3 ETO29449.1 - 3.8 7.5 11.4 4.8 7.2 7.9 1.2 1 0 0 1 1 1 0 YlqD protein RGS PF00615.14 ETO29451.1 - 3.3e-08 33.6 0.6 7.5e-08 32.4 0.4 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain Enkurin PF13864.1 ETO29453.1 - 2.7 8.2 7.7 0.14 12.3 0.6 2.5 2 2 0 2 2 2 0 Calmodulin-binding EIF_2_alpha PF07541.7 ETO29455.1 - 1.4e-30 105.2 0.0 2.9e-30 104.3 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 ETO29455.1 - 4.8e-10 39.3 0.5 8.5e-10 38.5 0.3 1.4 1 0 0 1 1 1 1 S1 RNA binding domain Lipoprotein_7 PF01540.11 ETO29456.1 - 0.025 13.6 1.9 0.033 13.2 1.3 1.2 1 0 0 1 1 1 0 Adhesin lipoprotein G-alpha PF00503.15 ETO29457.1 - 3.3e-35 121.5 0.1 3.8e-35 121.3 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit ABC_tran PF00005.22 ETO29457.1 - 0.00026 21.3 0.3 0.00041 20.6 0.2 1.2 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 ETO29457.1 - 0.0032 16.9 0.1 0.0054 16.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 ETO29457.1 - 0.006 17.3 0.1 0.0092 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETO29457.1 - 0.0085 16.0 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.16 ETO29457.1 - 0.018 14.1 0.0 0.032 13.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 ETO29457.1 - 0.026 14.0 0.2 0.052 13.0 0.0 1.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.1 ETO29457.1 - 0.035 13.9 0.2 0.056 13.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.14 ETO29457.1 - 0.061 12.5 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Pro_isomerase PF00160.16 ETO29457.1 - 0.067 13.3 0.1 0.088 13.0 0.0 1.3 1 0 0 1 1 1 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SART-1 PF03343.8 ETO29459.1 - 0.88 7.8 5.0 1.3 7.2 3.5 1.1 1 0 0 1 1 1 0 SART-1 family CPSF73-100_C PF11718.3 ETO29461.1 - 1.5e-05 24.4 6.3 5.5e-05 22.6 3.2 2.8 1 1 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term TPR_11 PF13414.1 ETO29462.1 - 5.7e-35 118.7 26.8 9.9e-10 37.9 0.1 5.7 3 1 3 6 6 6 6 TPR repeat TPR_17 PF13431.1 ETO29462.1 - 5.4e-26 88.5 22.3 0.00036 20.5 0.1 7.3 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETO29462.1 - 5.2e-20 70.1 27.8 1.1e-07 31.1 0.1 8.0 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO29462.1 - 1.4e-17 62.0 28.3 3.3e-07 29.7 0.0 8.5 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO29462.1 - 1.8e-16 60.2 8.8 0.0033 18.0 0.5 5.1 3 1 3 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 ETO29462.1 - 3.1e-16 59.0 30.4 8.2e-07 28.8 0.1 5.8 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 ETO29462.1 - 2.5e-14 52.4 2.2 0.0015 18.9 0.0 5.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO29462.1 - 2.6e-14 51.8 25.4 1.1e-05 24.9 0.1 7.4 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO29462.1 - 5e-12 44.6 17.3 0.00018 21.0 0.0 6.5 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO29462.1 - 3.8e-11 42.5 16.1 0.00011 21.9 0.0 5.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO29462.1 - 7.8e-10 38.9 12.0 0.068 13.5 0.0 4.7 3 1 1 4 4 4 4 Tetratricopeptide repeat TOM20_plant PF06552.7 ETO29462.1 - 0.0042 16.6 0.8 6.2 6.3 0.1 3.4 2 1 1 3 3 3 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_6 PF13174.1 ETO29462.1 - 0.0066 16.8 11.6 2.6 8.6 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat DHHA2 PF02833.9 ETO29462.1 - 0.0076 16.4 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 DHHA2 domain TPR_9 PF13371.1 ETO29462.1 - 0.064 13.1 0.6 17 5.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO29462.1 - 0.85 9.5 9.6 6.7 6.6 0.0 4.0 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat DUF3384 PF11864.3 ETO29465.1 - 0.015 13.7 9.0 0.025 13.0 6.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) Arb2 PF09757.4 ETO29467.1 - 1.2e-05 24.8 1.0 2.4e-05 23.8 0.7 1.5 1 0 0 1 1 1 1 Arb2 domain DUF912 PF06024.7 ETO29467.1 - 0.0025 17.8 2.7 0.0065 16.5 1.9 1.7 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3753 PF12575.3 ETO29467.1 - 0.0064 16.2 3.7 0.021 14.6 2.6 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3753) DUF2674 PF10879.3 ETO29467.1 - 0.048 13.3 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2674) Chorion_3 PF05387.6 ETO29467.1 - 2.3 7.6 4.8 4.1 6.7 3.3 1.3 1 0 0 1 1 1 0 Chorion family 3 Cytochrom_C_asm PF01578.15 ETO29470.1 - 0.12 11.8 2.5 0.14 11.7 1.7 1.2 1 0 0 1 1 1 0 Cytochrome C assembly protein Picorna_P3A PF06363.6 ETO29470.1 - 0.38 10.7 4.8 0.58 10.1 3.3 1.4 1 1 0 1 1 1 0 Picornaviridae P3A protein YABBY PF04690.8 ETO29470.1 - 1.2 9.3 3.8 0.88 9.7 0.6 1.9 1 1 1 2 2 2 0 YABBY protein GATase PF00117.23 ETO29471.1 - 5e-05 22.8 0.1 6.4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 ETO29471.1 - 0.0014 18.1 0.1 0.0021 17.5 0.0 1.4 1 1 0 1 1 1 1 Peptidase C26 DUF3647 PF12363.3 ETO29471.1 - 0.033 14.2 0.3 0.075 13.1 0.1 1.6 2 0 0 2 2 2 0 Phage protein Vps53_N PF04100.7 ETO29473.1 - 0.076 11.7 0.1 0.15 10.7 0.0 1.5 2 0 0 2 2 2 0 Vps53-like, N-terminal WD40 PF00400.27 ETO29474.1 - 5.9e-42 140.0 17.5 5.4e-09 35.5 0.1 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO29474.1 - 4.4e-05 21.8 1.9 0.67 8.0 0.0 4.4 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Baculo_19 PF04798.7 ETO29474.1 - 0.0087 15.4 0.0 0.13 11.6 0.0 2.3 2 0 0 2 2 2 1 Baculovirus 19 kDa protein conserved region Head_binding PF09008.5 ETO29474.1 - 5.3 7.0 7.8 1.7 8.7 0.5 2.8 3 0 0 3 3 3 0 Head binding Myc_N PF01056.13 ETO29475.1 - 7.7 5.5 8.1 12 4.8 5.6 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Lzipper-MIP1 PF14389.1 ETO29476.1 - 0.0036 17.3 8.1 0.014 15.5 5.6 2.0 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 DUF2183 PF09949.4 ETO29476.1 - 2.6 8.0 8.5 6.3 6.8 0.6 3.7 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2183) DivIC PF04977.10 ETO29476.1 - 8.7 5.9 16.1 1.3 8.5 4.4 3.4 1 1 1 2 2 2 0 Septum formation initiator DUF1673 PF07895.6 ETO29477.1 - 1.7 8.1 7.3 0.18 11.2 1.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) PIN_4 PF13638.1 ETO29478.1 - 0.0051 16.9 0.7 0.0051 16.9 0.5 2.1 3 0 0 3 3 3 1 PIN domain DUF489 PF04356.7 ETO29478.1 - 0.3 10.6 4.6 0.49 9.9 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF489) Glyco_hydro_38C PF07748.8 ETO29479.1 - 1.1e-29 103.5 0.4 2.3e-29 102.5 0.0 1.6 1 1 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain DUF4563 PF15124.1 ETO29479.1 - 0.011 15.3 0.0 0.025 14.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4563) CENP-F_leu_zip PF10473.4 ETO29480.1 - 0.0014 18.5 81.4 0.33 10.8 12.7 5.3 2 2 2 4 4 4 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.3 ETO29480.1 - 0.011 15.4 19.4 0.011 15.4 13.5 5.4 2 2 3 5 5 5 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 ETO29480.1 - 0.061 12.9 67.3 0.085 12.4 12.3 4.5 2 1 2 4 4 4 0 IncA protein GAS PF13851.1 ETO29480.1 - 0.083 12.0 82.4 0.18 10.9 15.8 4.2 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding FUSC PF04632.7 ETO29480.1 - 0.091 11.1 11.4 0.18 10.1 2.1 2.3 1 1 1 2 2 2 0 Fusaric acid resistance protein family Tropomyosin_1 PF12718.2 ETO29480.1 - 0.22 11.3 87.4 0.27 11.0 5.0 5.6 2 2 3 5 5 5 0 Tropomyosin like Exonuc_VII_S PF02609.11 ETO29480.1 - 0.27 11.0 9.6 0.28 10.9 0.5 4.1 3 0 0 3 3 3 0 Exonuclease VII small subunit Filament PF00038.16 ETO29480.1 - 1.5 8.2 67.2 0.82 9.0 7.0 4.2 1 1 2 3 3 3 0 Intermediate filament protein DUF869 PF05911.6 ETO29480.1 - 2.4 6.2 67.1 1.7 6.7 25.0 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) DUF1664 PF07889.7 ETO29480.1 - 3.3 7.5 50.7 0.027 14.2 5.3 5.3 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) Myosin_tail_1 PF01576.14 ETO29480.1 - 7.6 4.1 76.4 0.089 10.4 20.1 3.1 1 1 1 3 3 3 0 Myosin tail AAA_13 PF13166.1 ETO29480.1 - 8.1 4.7 69.5 0.21 9.9 8.7 3.1 1 1 2 3 3 3 0 AAA domain AAA_27 PF13514.1 ETO29480.1 - 8.9 3.8 54.9 0.35 8.5 14.7 2.5 1 1 1 2 2 2 0 AAA domain TPR_1 PF00515.23 ETO29481.1 - 0.0031 17.0 0.2 0.015 14.9 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TBPIP PF07106.8 ETO29481.1 - 0.0097 15.4 9.3 0.67 9.4 0.8 3.4 3 0 0 3 3 3 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TPR_11 PF13414.1 ETO29481.1 - 0.011 15.4 3.4 0.027 14.1 0.1 2.8 3 0 0 3 3 3 0 TPR repeat TPR_2 PF07719.12 ETO29481.1 - 0.014 15.2 1.7 0.092 12.7 0.1 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat Lzipper-MIP1 PF14389.1 ETO29481.1 - 0.026 14.5 0.5 0.026 14.5 0.4 2.4 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 TPR_8 PF13181.1 ETO29481.1 - 0.17 11.7 1.8 0.68 9.8 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1664 PF07889.7 ETO29481.1 - 0.29 10.9 7.8 4.4 7.1 0.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) TPR_19 PF14559.1 ETO29481.1 - 1.1 9.6 4.3 63 4.0 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 ETO29482.1 - 1.8e-14 53.1 13.9 1.7e-09 37.1 5.5 2.6 1 1 1 2 2 2 2 TPR repeat TPR_17 PF13431.1 ETO29482.1 - 7.1e-08 32.0 16.2 2.8e-05 23.9 1.3 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO29482.1 - 6.6e-06 26.3 6.8 0.03 14.9 0.3 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO29482.1 - 8.1e-06 25.3 18.8 0.037 13.9 0.9 4.2 3 2 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO29482.1 - 2.9e-05 24.6 12.9 0.0025 18.4 3.3 2.7 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO29482.1 - 3.4e-05 24.0 10.5 0.028 14.7 3.2 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO29482.1 - 4.7e-05 22.8 15.5 0.0082 15.7 0.0 4.4 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO29482.1 - 7.2e-05 22.6 18.8 0.00058 19.7 1.7 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO29482.1 - 9.3e-05 21.9 11.8 0.14 11.9 2.8 4.0 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETO29482.1 - 0.093 12.6 4.2 0.54 10.1 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO29482.1 - 0.21 10.8 1.3 16 4.8 0.1 2.6 2 0 0 2 2 2 0 SHNi-TPR Fis1_TPR_C PF14853.1 ETO29482.1 - 0.55 10.1 7.1 1.5 8.7 0.2 3.2 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat WD40 PF00400.27 ETO29483.1 - 7.9e-22 76.2 10.8 4.2e-07 29.5 0.0 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat PQQ_3 PF13570.1 ETO29483.1 - 0.14 12.4 0.0 1 9.7 0.0 2.5 2 0 0 2 2 2 0 PQQ-like domain DUF4201 PF13870.1 ETO29484.1 - 0.004 16.5 27.8 0.13 11.6 8.6 3.4 2 1 0 3 3 3 2 Domain of unknown function (DUF4201) DUF4279 PF14106.1 ETO29484.1 - 0.12 12.2 2.5 0.63 9.9 0.0 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4279) V-ATPase_H_C PF11698.3 ETO29484.1 - 0.25 11.2 6.8 0.072 13.0 2.2 1.9 2 0 0 2 2 2 0 V-ATPase subunit H DUF4094 PF13334.1 ETO29484.1 - 0.3 11.5 0.1 0.3 11.5 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) DivIC PF04977.10 ETO29484.1 - 0.37 10.2 25.6 2 7.9 1.1 5.2 5 0 0 5 5 5 0 Septum formation initiator DDE_Tnp_1_3 PF13612.1 ETO29484.1 - 1.1 9.0 6.3 0.15 11.7 0.4 2.1 2 1 0 2 2 2 0 Transposase DDE domain Tropomyosin_1 PF12718.2 ETO29484.1 - 8.7 6.1 24.9 1.1 9.1 1.9 4.0 4 0 0 4 4 4 0 Tropomyosin like SseC PF04888.7 ETO29484.1 - 9 5.5 10.3 0.45 9.7 1.8 2.3 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family Kinesin PF00225.18 ETO29485.1 - 2.1e-15 56.2 0.6 2.1e-15 56.2 0.4 2.0 2 1 1 3 3 3 1 Kinesin motor domain Ank_4 PF13637.1 ETO29486.1 - 3.2e-06 27.5 0.1 9.4e-05 22.8 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO29486.1 - 7.4e-05 22.6 0.0 0.056 13.7 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 ETO29486.1 - 0.00015 21.9 0.0 0.00063 19.9 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO29486.1 - 0.00067 19.9 0.0 0.0036 17.6 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO29486.1 - 0.0013 18.4 0.0 2 8.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Peptidase_S76 PF13611.1 ETO29486.1 - 0.87 9.7 6.7 0.14 12.2 1.2 2.4 2 0 0 2 2 2 0 Serine peptidase of plant viral polyprotein, P1 Tubulin PF00091.20 ETO29488.1 - 1.6e-37 129.4 0.0 3.3e-37 128.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO29488.1 - 1.7e-24 86.2 0.7 2.7e-20 72.6 0.2 2.3 2 0 0 2 2 2 2 Tubulin C-terminal domain Thiolase_C PF02803.13 ETO29489.1 - 1.8e-41 140.3 0.0 3.1e-41 139.6 0.0 1.3 1 0 0 1 1 1 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 ETO29489.1 - 7.1e-28 97.3 1.6 2.8e-16 59.2 0.1 2.2 2 0 0 2 2 2 2 Thiolase, N-terminal domain Chorion_2 PF03964.10 ETO29490.1 - 0.0027 18.2 1.1 0.0053 17.2 0.8 1.5 1 0 0 1 1 1 1 Chorion family 2 SOBP PF15279.1 ETO29490.1 - 0.19 12.0 8.7 0.21 11.9 6.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Peptidase_S64 PF08192.6 ETO29490.1 - 1.5 7.0 12.4 1.9 6.7 8.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF1675 PF07897.6 ETO29490.1 - 6.5 6.5 12.4 11 5.7 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) SR-25 PF10500.4 ETO29490.1 - 7 6.0 32.4 0.45 9.9 14.0 2.2 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein MRP-L47 PF06984.8 ETO29491.1 - 0.0022 17.8 0.7 0.0022 17.8 0.5 2.2 2 1 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Potyvirid-P3 PF13608.1 ETO29491.1 - 0.015 14.4 2.6 0.019 14.1 1.8 1.1 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein CTD_bind PF04818.8 ETO29491.1 - 0.034 14.4 0.2 0.19 11.9 0.0 2.2 2 1 0 2 2 2 0 RNA polymerase II-binding domain. Exonuc_VII_L PF02601.10 ETO29491.1 - 0.18 10.9 2.4 0.19 10.8 1.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CCER1 PF15482.1 ETO29492.1 - 0.014 15.0 1.7 0.026 14.1 1.2 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 SAM_1 PF00536.25 ETO29493.1 - 8.2e-10 38.7 0.0 1.5e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO29493.1 - 2.3e-09 36.9 0.0 9.5e-09 34.9 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 ETO29493.1 - 0.022 14.4 0.5 0.057 13.1 0.3 1.6 1 1 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Img2 PF05046.9 ETO29493.1 - 0.084 13.1 0.1 0.34 11.1 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) U79_P34 PF03064.11 ETO29494.1 - 0.75 9.2 8.6 1.1 8.7 5.9 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CobT PF06213.7 ETO29494.1 - 4.6 6.2 9.6 6.5 5.7 6.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT IFT57 PF10498.4 ETO29495.1 - 7.6e-05 21.6 28.0 8.8e-05 21.4 19.4 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Atg14 PF10186.4 ETO29495.1 - 0.0025 16.8 25.6 0.0035 16.3 17.8 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 ETO29495.1 - 0.014 13.2 22.0 0.019 12.8 15.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.3 ETO29495.1 - 0.027 14.2 16.3 0.027 14.2 11.3 3.0 1 1 2 3 3 2 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 ETO29495.1 - 0.14 11.1 29.6 0.21 10.6 20.5 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 ETO29495.1 - 0.15 11.6 34.5 8.6 5.9 23.6 2.1 1 1 0 1 1 1 0 IncA protein Reo_sigmaC PF04582.7 ETO29495.1 - 0.18 10.9 1.0 0.22 10.6 0.7 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein ATG16 PF08614.6 ETO29495.1 - 0.25 11.1 30.9 0.43 10.3 21.4 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4279 PF14106.1 ETO29495.1 - 0.55 10.1 3.4 0.51 10.2 0.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4279) Baculo_PEP_C PF04513.7 ETO29495.1 - 0.71 9.7 4.6 1.3 8.8 3.1 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus YlqD PF11068.3 ETO29495.1 - 0.77 9.7 34.6 1.2 9.2 5.3 2.3 1 1 1 2 2 2 0 YlqD protein AAA_23 PF13476.1 ETO29495.1 - 0.83 9.9 25.9 1.2 9.4 17.9 1.3 1 0 0 1 1 1 0 AAA domain DUF948 PF06103.6 ETO29495.1 - 0.86 9.4 4.9 2.4 8.1 3.2 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) SBP PF03110.9 ETO29495.1 - 1.4 9.1 8.5 0.25 11.5 1.3 2.7 2 1 1 3 3 3 0 SBP domain DUF1664 PF07889.7 ETO29495.1 - 1.5 8.6 14.9 0.17 11.6 5.1 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF763 PF05559.6 ETO29495.1 - 2.3 7.1 10.1 2.9 6.7 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF763) RE_Alw26IDE PF09665.5 ETO29495.1 - 2.3 6.8 18.2 2.7 6.6 12.6 1.1 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) ERM PF00769.14 ETO29495.1 - 2.5 7.5 38.9 3.7 7.0 26.6 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family BLOC1_2 PF10046.4 ETO29495.1 - 2.5 8.2 20.8 0.26 11.4 6.6 2.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF743 PF05332.6 ETO29495.1 - 3.7 7.5 17.4 0.039 13.8 3.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF743) Rootletin PF15035.1 ETO29495.1 - 4.5 7.1 31.3 7.4 6.5 21.5 1.4 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Spc7 PF08317.6 ETO29495.1 - 4.6 5.8 30.8 3.2 6.3 15.6 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein TMPIT PF07851.8 ETO29495.1 - 6.6 5.7 25.7 0.94 8.4 12.9 2.0 1 1 1 2 2 2 0 TMPIT-like protein DUF730 PF05325.6 ETO29495.1 - 7.2 6.4 11.5 0.1 12.3 2.2 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF730) DUF2852 PF11014.3 ETO29496.1 - 0.02 14.8 1.2 0.03 14.2 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) Rifin_STEVOR PF02009.11 ETO29496.1 - 0.024 14.2 2.2 0.033 13.8 0.3 1.8 1 1 1 2 2 2 0 Rifin/stevor family Med11 PF10280.4 ETO29496.1 - 0.042 13.8 4.6 0.055 13.5 3.2 1.2 1 0 0 1 1 1 0 Mediator complex protein DUF4201 PF13870.1 ETO29496.1 - 0.074 12.4 10.6 0.24 10.8 7.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) GAS PF13851.1 ETO29496.1 - 0.081 12.1 10.6 0.11 11.7 7.3 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3740 PF12548.3 ETO29496.1 - 0.11 12.8 0.4 0.11 12.8 0.3 2.1 1 1 1 2 2 2 0 Sulfatase protein DUF4071 PF13281.1 ETO29496.1 - 0.13 11.1 2.3 0.15 10.8 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) DUF904 PF06005.7 ETO29496.1 - 0.5 10.6 15.0 2.1 8.6 5.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Viral_P18 PF04521.8 ETO29496.1 - 1.2 8.5 6.1 0.18 11.2 0.8 1.9 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Tup_N PF08581.5 ETO29496.1 - 1.6 8.9 8.2 9.3 6.5 0.2 2.2 2 0 0 2 2 2 0 Tup N-terminal Golgin_A5 PF09787.4 ETO29496.1 - 1.8 6.9 10.4 2.2 6.6 7.2 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 TSC22 PF01166.13 ETO29496.1 - 2.1 8.3 7.6 5.9 6.9 2.9 2.4 1 1 1 2 2 2 0 TSC-22/dip/bun family Kelch_6 PF13964.1 ETO29497.1 - 1.4e-06 28.1 2.7 0.25 11.6 0.2 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO29497.1 - 1.9e-05 24.2 2.7 0.32 10.8 0.3 4.4 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.1 ETO29497.1 - 8.8e-05 22.3 0.3 4.6 7.2 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO29497.1 - 0.00012 21.5 6.1 0.0035 16.8 0.3 3.5 3 0 0 3 3 3 2 Kelch motif SRP54_N PF02881.14 ETO29498.1 - 0.02 14.9 0.4 0.3 11.2 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain Pex24p PF06398.6 ETO29499.1 - 4.1 6.1 8.8 0.18 10.5 0.5 2.4 2 1 0 2 2 2 0 Integral peroxisomal membrane peroxin DUF667 PF05018.8 ETO29500.1 - 3.2e-61 205.9 1.1 5.6e-61 205.1 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Pox_A30L_A26L PF06086.7 ETO29500.1 - 0.22 10.9 4.8 0.12 11.8 1.0 1.8 1 1 1 2 2 2 0 Orthopoxvirus A26L/A30L protein PI3K_p85B PF02192.11 ETO29503.1 - 0.071 12.5 0.1 0.27 10.6 0.0 2.0 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain WD40 PF00400.27 ETO29504.1 - 1.1e-81 265.9 16.4 3.5e-11 42.5 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO29504.1 - 1.7e-10 40.9 1.1 0.00086 19.0 0.0 3.7 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO29504.1 - 7.7e-06 24.3 3.0 0.2 9.7 0.2 5.2 1 1 1 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO29504.1 - 2.7e-05 23.1 12.8 0.91 8.2 0.1 6.0 3 2 2 5 5 5 3 Nup133 N terminal like Nbas_N PF15492.1 ETO29504.1 - 4e-05 22.8 2.3 3 6.8 0.0 4.2 2 2 2 4 4 4 3 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 ETO29504.1 - 0.00032 20.3 13.6 1.3 8.7 0.0 6.5 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO29504.1 - 0.00038 20.0 1.1 1.3 8.4 0.1 3.1 1 1 1 3 3 3 1 PQQ-like domain DUF1258 PF06869.7 ETO29504.1 - 0.0026 16.8 0.1 0.45 9.5 0.0 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF1258) Cytochrom_D1 PF02239.11 ETO29504.1 - 0.0055 15.0 1.6 5.1 5.2 0.0 3.5 2 1 2 4 4 4 2 Cytochrome D1 heme domain Resistin PF06954.6 ETO29504.1 - 0.011 16.0 0.2 39 4.6 0.0 4.3 4 1 2 6 6 5 0 Resistin DUF1797 PF08796.5 ETO29504.1 - 0.02 14.7 0.0 0.26 11.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1797) MMS1_N PF10433.4 ETO29504.1 - 0.031 12.4 0.0 4.7 5.2 0.0 3.1 1 1 3 4 4 4 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Vac_Fusion PF02346.11 ETO29504.1 - 0.047 13.1 0.1 7.8 5.9 0.0 3.2 3 0 0 3 3 3 0 Chordopoxvirus fusion protein Proteasome_A_N PF10584.4 ETO29504.1 - 4.7 6.6 8.0 13 5.2 0.1 4.2 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 ETO29505.1 - 7.6e-74 241.1 14.9 3e-11 42.7 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO29505.1 - 8e-13 48.5 0.1 1.2e-05 25.1 0.0 3.3 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO29505.1 - 3.5e-08 32.1 0.7 0.025 12.8 0.1 3.2 1 1 2 3 3 3 3 Cytochrome D1 heme domain PD40 PF07676.7 ETO29505.1 - 1.8e-06 27.4 2.3 2.3 7.9 0.0 5.4 6 0 0 6 6 6 3 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 ETO29505.1 - 0.00072 18.7 1.1 0.88 8.6 0.0 3.9 1 1 3 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 ETO29505.1 - 0.0014 17.8 1.6 23 4.4 0.0 5.0 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Resistin PF06954.6 ETO29505.1 - 0.01 16.1 0.8 5.7 7.2 0.0 4.5 2 2 2 4 4 4 0 Resistin Macro PF01661.16 ETO29507.1 - 2.9e-38 130.4 0.2 5.2e-38 129.5 0.1 1.4 1 0 0 1 1 1 1 Macro domain Lipase_GDSL PF00657.17 ETO29508.1 - 0.043 13.6 0.5 0.18 11.6 0.1 1.9 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase SWIB PF02201.13 ETO29509.1 - 0.0056 16.3 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain BLVR PF06375.6 ETO29511.1 - 0.02 14.7 10.1 0.03 14.1 7.0 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) DUF3043 PF11241.3 ETO29511.1 - 0.04 13.5 1.6 0.057 13.0 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Toxin_trans PF07952.7 ETO29511.1 - 0.048 12.5 3.4 0.057 12.3 2.4 1.1 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain TSGP1 PF07771.6 ETO29511.1 - 0.087 12.6 7.0 0.18 11.6 4.9 1.4 1 0 0 1 1 1 0 Tick salivary peptide group 1 LicD PF04991.8 ETO29511.1 - 0.25 11.4 3.8 0.28 11.2 2.7 1.2 1 0 0 1 1 1 0 LicD family GAGA_bind PF06217.7 ETO29511.1 - 0.37 10.7 11.0 0.44 10.4 7.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Muted PF14942.1 ETO29511.1 - 1.8 8.4 13.0 0.37 10.6 6.2 1.8 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Med19 PF10278.4 ETO29511.1 - 1.9 8.1 15.5 2.9 7.5 10.8 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF4337 PF14235.1 ETO29511.1 - 2.5 7.9 8.2 0.53 10.1 3.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Peptidase_S49_N PF08496.5 ETO29511.1 - 5.3 6.8 9.5 8.1 6.2 6.6 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Vpu PF00558.14 ETO29511.1 - 6.7 6.3 7.2 7.3 6.2 3.6 2.1 2 0 0 2 2 2 0 Vpu protein Pyridoxal_deC PF00282.14 ETO29512.1 - 2.5e-08 32.7 0.0 3.6e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF1577 PF07614.6 ETO29513.1 - 0.022 13.6 0.3 0.034 13.0 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1577) zf-Di19 PF05605.7 ETO29514.1 - 0.047 13.8 1.0 0.11 12.5 0.7 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Nop14 PF04147.7 ETO29514.1 - 0.17 9.7 20.9 0.25 9.2 14.5 1.2 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.6 ETO29514.1 - 0.44 10.0 31.2 0.031 13.8 14.6 2.2 2 0 0 2 2 2 0 PPP4R2 DUF1840 PF08895.6 ETO29514.1 - 0.59 10.1 7.2 0.17 11.9 2.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Peptidase_S49_N PF08496.5 ETO29514.1 - 1.7 8.4 10.3 10 5.8 3.9 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DDHD PF02862.12 ETO29514.1 - 3.9 7.2 17.7 1.1 8.9 9.8 1.8 2 0 0 2 2 2 0 DDHD domain RNA_pol_3_Rpc31 PF11705.3 ETO29514.1 - 5 7.0 22.0 10 5.9 15.2 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Xpo1 PF08389.7 ETO29515.1 - 0.085 12.7 3.4 0.054 13.4 0.9 1.7 2 0 0 2 2 2 0 Exportin 1-like protein DUF1985 PF09331.6 ETO29515.1 - 4 7.2 8.8 5.1 6.8 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1985) DUF2796 PF10986.3 ETO29516.1 - 0.12 12.2 14.5 2.1 8.3 5.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) YL1 PF05764.8 ETO29516.1 - 0.31 10.6 33.4 0.84 9.1 9.5 2.2 2 0 0 2 2 2 0 YL1 nuclear protein Peptidase_A21 PF03566.8 ETO29516.1 - 0.69 7.9 5.2 0.83 7.6 3.6 1.1 1 0 0 1 1 1 0 Peptidase family A21 Afi1 PF07792.7 ETO29516.1 - 2.4 8.1 14.6 0.73 9.8 2.2 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2011 PF09428.5 ETO29516.1 - 4.4 7.2 28.4 7.1 6.5 1.2 2.2 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF2011) RNA_polI_A34 PF08208.6 ETO29516.1 - 6.4 6.4 36.9 5.3 6.6 5.6 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 RNase_H2-Ydr279 PF09468.5 ETO29516.1 - 7.5 5.6 23.5 0.76 8.9 0.5 2.1 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) TLP-20 PF06088.6 ETO29516.1 - 9.1 5.9 18.3 0.53 9.9 1.8 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Kelch_6 PF13964.1 ETO29517.1 - 5.3e-06 26.3 4.5 0.0071 16.4 0.6 4.1 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO29517.1 - 1.8e-05 24.1 4.1 0.00099 18.6 1.5 3.2 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO29517.1 - 0.00044 19.9 6.4 0.013 15.1 0.3 3.8 4 1 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO29517.1 - 0.00074 19.2 0.5 0.0098 15.6 0.1 2.8 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO29517.1 - 0.028 14.3 1.3 1.3 9.0 0.6 3.3 3 0 0 3 3 3 0 Kelch motif DUF4087 PF13316.1 ETO29517.1 - 0.12 12.5 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4087) AdoMet_dc PF02675.10 ETO29520.1 - 0.097 12.5 0.1 0.31 10.9 0.0 1.8 1 1 0 1 1 1 0 S-adenosylmethionine decarboxylase LicD PF04991.8 ETO29520.1 - 0.099 12.7 5.3 0.047 13.7 1.5 1.8 2 0 0 2 2 2 0 LicD family DUF4047 PF13256.1 ETO29520.1 - 0.15 12.0 3.5 0.16 11.9 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) GCOM2 PF15328.1 ETO29520.1 - 0.79 9.4 7.5 0.45 10.2 1.2 2.1 1 1 1 2 2 2 0 Putative GRINL1B complex locus protein 2 PRMT5 PF05185.11 ETO29521.1 - 2.1e-12 46.7 0.4 2.8e-12 46.2 0.2 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_31 PF13847.1 ETO29521.1 - 7.3e-11 41.8 0.1 1.8e-10 40.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETO29521.1 - 1.2e-08 34.9 0.0 2.2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 ETO29521.1 - 1.4e-08 34.2 0.2 3.1e-08 33.0 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 ETO29521.1 - 2.2e-08 34.6 0.0 7.8e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETO29521.1 - 7.8e-06 26.2 0.0 2.2e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETO29521.1 - 4.6e-05 23.2 0.0 9.6e-05 22.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETO29521.1 - 0.00016 21.0 0.1 0.00032 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 ETO29521.1 - 0.0019 16.9 0.0 0.0027 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.15 ETO29521.1 - 0.0024 17.0 0.0 0.0036 16.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DOT1 PF08123.8 ETO29521.1 - 0.0025 17.1 0.1 0.0077 15.5 0.0 1.8 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_12 PF08242.7 ETO29521.1 - 0.0072 16.7 0.0 0.017 15.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETO29521.1 - 0.012 15.9 0.0 0.027 14.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 ETO29521.1 - 0.013 15.0 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.10 ETO29521.1 - 0.062 12.6 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 FtsJ PF01728.14 ETO29521.1 - 0.12 12.3 1.3 0.56 10.1 0.9 2.0 1 1 0 1 1 1 0 FtsJ-like methyltransferase Rhodanese PF00581.15 ETO29523.1 - 3.6e-16 59.5 0.2 1e-15 58.0 0.1 1.8 1 1 0 2 2 2 1 Rhodanese-like domain Folate_carrier PF01770.13 ETO29523.1 - 0.086 11.3 0.3 0.11 10.9 0.2 1.2 1 0 0 1 1 1 0 Reduced folate carrier Vpu PF00558.14 ETO29523.1 - 0.095 12.2 1.0 0.11 12.0 0.1 1.7 2 0 0 2 2 2 0 Vpu protein Neuromodulin_N PF10580.4 ETO29523.1 - 0.1 12.2 0.7 0.61 9.7 0.4 2.1 2 0 0 2 2 2 0 Gap junction protein N-terminal region Ion_trans PF00520.26 ETO29525.1 - 5.8e-26 90.9 10.2 1.5e-22 79.8 1.0 3.0 3 0 0 3 3 3 2 Ion transport protein CDC45 PF02724.9 ETO29525.1 - 0.004 15.2 4.3 0.006 14.6 0.0 2.1 2 0 0 2 2 2 1 CDC45-like protein Pex14_N PF04695.8 ETO29525.1 - 0.025 14.6 5.6 0.13 12.3 4.0 2.0 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region LCE PF14672.1 ETO29525.1 - 0.058 13.8 0.2 0.058 13.8 0.1 2.4 3 0 0 3 3 3 0 Late cornified envelope RR_TM4-6 PF06459.7 ETO29525.1 - 0.39 10.5 13.4 0.037 13.9 3.8 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Sigma_reg_N PF13800.1 ETO29525.1 - 0.54 10.3 5.7 8.4 6.5 0.1 3.3 2 1 1 3 3 3 0 Sigma factor regulator N-terminal SprA-related PF12118.3 ETO29525.1 - 1.1 8.5 19.1 0.037 13.3 7.6 1.9 2 0 0 2 2 2 0 SprA-related family Tom37_C PF11801.3 ETO29525.1 - 1.3 8.8 10.4 1.4 8.7 3.5 2.2 2 0 0 2 2 2 0 Tom37 C-terminal domain Voldacs PF03517.8 ETO29525.1 - 1.7 8.5 9.9 0.12 12.2 0.3 2.8 2 1 1 3 3 3 0 Regulator of volume decrease after cellular swelling DUF4484 PF14831.1 ETO29525.1 - 1.8 8.6 9.9 0.94 9.5 1.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) Daxx PF03344.10 ETO29526.1 - 0.049 12.1 24.0 0.061 11.8 16.7 1.1 1 0 0 1 1 1 0 Daxx Family DUF843 PF05814.6 ETO29526.1 - 0.19 11.5 1.3 0.39 10.5 0.1 2.1 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) DUF481 PF04338.7 ETO29527.1 - 0.013 15.2 1.6 0.024 14.3 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF481 Vps4_C PF09336.5 ETO29528.1 - 3.7e-07 29.9 0.0 6.9e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain S_100 PF01023.14 ETO29528.1 - 1 8.7 4.0 0.28 10.5 0.4 1.8 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain DUF2151 PF10221.4 ETO29529.1 - 0.026 12.7 1.3 0.03 12.4 0.9 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Snf7 PF03357.16 ETO29529.1 - 0.34 10.2 7.9 0.37 10.1 5.5 1.0 1 0 0 1 1 1 0 Snf7 DUF504 PF04457.7 ETO29531.1 - 0.026 14.6 0.0 0.091 12.9 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF504) DUF2827 PF10933.3 ETO29531.1 - 0.11 10.9 0.0 0.14 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2827) SAP PF02037.22 ETO29532.1 - 6.3e-05 22.3 1.2 0.00012 21.5 0.8 1.5 1 0 0 1 1 1 1 SAP domain MATH PF00917.21 ETO29532.1 - 0.0031 17.7 1.8 0.024 14.8 1.2 2.3 1 1 0 1 1 1 1 MATH domain BTB PF00651.26 ETO29533.1 - 5.8e-19 68.1 1.9 9.9e-19 67.3 0.2 2.1 2 1 0 2 2 2 1 BTB/POZ domain BACK PF07707.10 ETO29533.1 - 0.0023 17.7 0.6 0.0057 16.4 0.1 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch DUF4251 PF14059.1 ETO29533.1 - 0.029 14.1 0.5 0.064 13.0 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4251) WAK PF08488.6 ETO29533.1 - 0.063 13.5 0.2 0.063 13.5 0.2 1.7 2 0 0 2 2 2 0 Wall-associated kinase RRM_1 PF00076.17 ETO29534.1 - 1.5e-32 111.0 0.8 1.2e-18 66.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO29534.1 - 1.7e-18 66.3 0.1 3.2e-10 39.8 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO29534.1 - 2.3e-08 33.7 0.0 0.0063 16.3 0.0 3.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETO29534.1 - 0.071 12.8 0.0 0.65 9.8 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif ICMT PF04140.9 ETO29535.1 - 1.2e-18 67.0 0.1 2e-18 66.3 0.1 1.3 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 ETO29535.1 - 1.2e-12 47.8 0.7 2.2e-12 47.0 0.5 1.4 1 0 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 ETO29535.1 - 7.9e-07 27.9 0.4 7.9e-07 27.9 0.3 1.4 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.11 ETO29535.1 - 0.005 16.6 3.3 0.0074 16.0 1.9 1.5 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase HlyD_2 PF12700.2 ETO29536.1 - 0.15 11.1 16.9 0.79 8.8 0.3 2.4 2 0 0 2 2 2 0 HlyD family secretion protein DUF4407 PF14362.1 ETO29536.1 - 4.8 6.0 5.4 0.37 9.6 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) BcrAD_BadFG PF01869.15 ETO29539.1 - 0.0033 16.7 0.0 0.0051 16.1 0.0 1.3 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family HSP70 PF00012.15 ETO29539.1 - 0.039 11.8 0.0 0.25 9.1 0.0 2.0 2 0 0 2 2 2 0 Hsp70 protein GST_N_2 PF13409.1 ETO29540.1 - 0.073 13.0 0.0 0.093 12.7 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Sec20 PF03908.8 ETO29541.1 - 0.037 13.7 0.0 0.053 13.2 0.0 1.2 1 0 0 1 1 1 0 Sec20 Nab2 PF11517.3 ETO29542.1 - 0.085 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) HSP70 PF00012.15 ETO29543.1 - 0.021 12.7 0.0 0.3 8.9 0.0 2.1 1 1 0 2 2 2 0 Hsp70 protein Hydantoinase_A PF01968.13 ETO29543.1 - 0.079 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase DUF2142 PF09913.4 ETO29544.1 - 0.019 13.6 0.1 0.032 12.9 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) Cut8_C PF08559.5 ETO29545.1 - 0.028 14.2 0.0 0.39 10.5 0.0 2.4 2 0 0 2 2 2 0 Cut8 six-helix bundle Rifin_STEVOR PF02009.11 ETO29545.1 - 0.032 13.8 0.5 0.032 13.8 0.4 1.9 2 0 0 2 2 2 0 Rifin/stevor family TraC PF07820.7 ETO29545.1 - 0.19 11.9 0.0 0.41 10.8 0.0 1.5 1 0 0 1 1 1 0 TraC-like protein TRAPP PF04051.11 ETO29546.1 - 1e-32 112.7 0.0 1.3e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF3469 PF11952.3 ETO29547.1 - 6.4 6.5 7.1 1.5 8.5 0.2 2.7 2 1 2 4 4 4 0 Protein of unknown function (DUF3469) Kelch_4 PF13418.1 ETO29548.1 - 3.5e-05 23.4 0.3 0.0044 16.7 0.0 3.4 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO29548.1 - 0.043 13.5 0.6 0.28 11.0 0.0 2.6 2 0 0 2 2 2 0 Kelch motif GTP_EFTU PF00009.22 ETO29549.1 - 1.1e-45 155.4 0.0 1.7e-45 154.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 ETO29549.1 - 5.6e-33 113.0 0.0 1.5e-32 111.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 ETO29549.1 - 1.6e-28 98.3 0.0 3.9e-28 97.1 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 ETO29549.1 - 1e-20 73.3 0.0 2.6e-20 72.0 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 ETO29549.1 - 1.2e-07 31.7 0.1 5.3e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 AIG1 PF04548.11 ETO29549.1 - 0.015 14.3 0.1 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 AIG1 family MMR_HSR1 PF01926.18 ETO29549.1 - 0.022 14.7 0.1 0.073 13.0 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase BTD PF09270.5 ETO29549.1 - 0.052 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Beta-trefoil DNA-binding domain Aa_trans PF01490.13 ETO29550.1 - 2.9e-18 65.5 0.2 4.3e-18 64.9 0.1 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3353 PF11833.3 ETO29550.1 - 0.034 13.6 5.3 0.048 13.1 1.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3353) Tox-REase-3 PF15647.1 ETO29551.1 - 0.00096 18.9 0.5 0.0023 17.7 0.1 1.7 1 1 1 2 2 2 1 Restriction endonuclease fold toxin 3 V_ATPase_I PF01496.14 ETO29552.1 - 1.4e-161 539.0 10.8 1.4e-159 532.4 7.5 2.0 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family RNase_T PF00929.19 ETO29553.1 - 2e-21 76.9 0.6 2.1e-20 73.6 0.4 2.0 1 1 0 1 1 1 1 Exonuclease FoP_duplication PF13865.1 ETO29554.1 - 0.0015 18.9 2.3 0.0015 18.9 1.6 3.7 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 WD40 PF00400.27 ETO29555.1 - 9.1e-73 237.7 16.4 1.3e-12 47.1 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO29555.1 - 9.4e-08 30.6 6.5 0.48 8.5 1.1 5.5 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO29555.1 - 4.3e-05 21.9 0.3 0.011 14.0 0.0 3.0 2 1 1 3 3 3 1 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO29555.1 - 0.0034 16.8 2.3 0.23 10.8 1.6 3.1 1 1 1 2 2 2 2 PQQ-like domain Resistin PF06954.6 ETO29555.1 - 0.046 13.9 2.8 58 4.0 0.0 5.0 2 2 3 6 6 6 0 Resistin Pox_Ag35 PF03286.9 ETO29556.1 - 0.011 15.3 6.4 0.011 15.3 4.4 2.1 2 1 0 2 2 2 0 Pox virus Ag35 surface protein AAA PF00004.24 ETO29557.1 - 3.9e-44 150.0 0.0 4.9e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETO29557.1 - 7.3e-07 29.3 0.0 0.00027 20.9 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 ETO29557.1 - 1.3e-06 28.5 0.0 0.00011 22.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 ETO29557.1 - 3.2e-06 26.3 0.0 9.1e-06 24.8 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 ETO29557.1 - 1.9e-05 24.4 0.1 0.00045 19.9 0.1 2.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 ETO29557.1 - 2.1e-05 25.3 0.0 2.7e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 ETO29557.1 - 0.00013 21.8 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 ETO29557.1 - 0.00018 20.9 0.0 0.00027 20.4 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 ETO29557.1 - 0.00026 20.6 0.0 0.00061 19.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 ETO29557.1 - 0.0006 19.9 0.0 0.0019 18.3 0.0 1.8 2 0 0 2 2 2 1 RNA helicase AAA_2 PF07724.9 ETO29557.1 - 0.00085 19.2 0.0 0.002 18.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 ETO29557.1 - 0.0011 17.7 0.0 0.0017 17.1 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 ETO29557.1 - 0.0016 17.6 0.1 0.0045 16.1 0.0 1.7 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 ETO29557.1 - 0.0042 16.2 0.0 0.0058 15.7 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_24 PF13479.1 ETO29557.1 - 0.01 15.4 0.1 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 ETO29557.1 - 0.013 15.4 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 ETO29557.1 - 0.014 14.8 0.0 0.12 11.7 0.0 2.4 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 ETO29557.1 - 0.016 14.4 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_3 PF07726.6 ETO29557.1 - 0.018 14.6 0.0 0.027 14.0 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 ETO29557.1 - 0.02 13.8 0.0 0.037 12.9 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.7 ETO29557.1 - 0.02 14.5 0.9 0.28 10.8 0.0 2.5 3 0 0 3 3 3 0 NACHT domain AAA_28 PF13521.1 ETO29557.1 - 0.021 14.8 0.0 0.038 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 ETO29557.1 - 0.025 14.9 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 ETO29557.1 - 0.029 13.7 0.2 0.07 12.5 0.2 1.7 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 ETO29557.1 - 0.032 14.2 0.0 0.066 13.2 0.0 1.5 1 1 0 1 1 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 ETO29557.1 - 0.045 13.4 0.0 0.9 9.1 0.0 2.1 1 1 1 2 2 2 0 Archaeal ATPase ABC_tran PF00005.22 ETO29557.1 - 0.049 13.9 0.0 0.069 13.4 0.0 1.5 1 1 0 1 1 1 0 ABC transporter UPF0079 PF02367.12 ETO29557.1 - 0.072 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 KaiC PF06745.8 ETO29557.1 - 0.086 11.9 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 KaiC Parvo_NS1 PF01057.12 ETO29557.1 - 0.09 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 ETO29557.1 - 0.1 12.1 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 ETO29557.1 - 0.12 11.3 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 ETO29557.1 - 0.13 11.1 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein NB-ARC PF00931.17 ETO29557.1 - 0.13 11.0 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain SCHIP-1 PF10148.4 ETO29558.1 - 0.62 9.4 4.4 0.69 9.2 3.1 1.1 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 NPR3 PF03666.8 ETO29558.1 - 0.68 8.3 5.1 0.68 8.3 3.6 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 eIF-3c_N PF05470.7 ETO29558.1 - 2.6 6.0 15.6 2.9 5.8 10.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Bud13 PF09736.4 ETO29558.1 - 3 8.1 13.4 3.6 7.8 9.3 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF2201_N PF13203.1 ETO29558.1 - 4 6.5 9.5 4.6 6.3 6.6 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain PfkB PF00294.19 ETO29559.1 - 4e-43 147.6 0.2 1.6e-42 145.7 0.1 1.8 1 1 0 1 1 1 1 pfkB family carbohydrate kinase zf-CXXC PF02008.15 ETO29559.1 - 0.053 13.3 1.2 0.13 12.1 0.9 1.6 1 0 0 1 1 1 0 CXXC zinc finger domain Apolipoprotein PF01442.13 ETO29560.1 - 0.0019 17.7 0.9 0.0019 17.7 0.7 1.8 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain Mnd1 PF03962.10 ETO29560.1 - 0.0079 15.8 4.9 0.0079 15.8 3.4 2.5 2 0 0 2 2 2 1 Mnd1 family Baculo_PEP_C PF04513.7 ETO29560.1 - 0.15 11.9 0.4 0.34 10.7 0.3 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_GPO PF05929.6 ETO29560.1 - 1.5 7.9 7.4 0.11 11.7 1.3 1.8 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Glyoxalase PF00903.20 ETO29561.1 - 7.5e-08 32.4 0.0 1.1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 ETO29561.1 - 2.7e-07 31.1 0.0 4e-07 30.6 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 ETO29561.1 - 0.00022 21.2 0.0 0.00039 20.3 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Rsm1 PF08600.5 ETO29562.1 - 0.088 12.6 0.6 0.38 10.6 0.4 2.1 1 0 0 1 1 1 0 Rsm1-like Acetyltransf_1 PF00583.19 ETO29563.1 - 2.1e-09 37.2 0.0 3.9e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETO29563.1 - 7.9e-07 29.1 0.0 1.3e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETO29563.1 - 0.043 13.6 0.0 0.13 12.1 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PRP1_N PF06424.7 ETO29564.1 - 0.0085 16.4 4.7 0.0099 16.1 3.3 1.1 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal CENP-B_dimeris PF09026.5 ETO29564.1 - 0.02 15.1 2.8 0.027 14.6 2.0 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain YafO_toxin PF13957.1 ETO29564.1 - 0.047 13.4 0.3 0.19 11.5 0.0 1.9 1 1 1 2 2 2 0 Toxin YafO, type II toxin-antitoxin system Nucleoplasmin PF03066.10 ETO29564.1 - 0.055 12.9 4.3 0.076 12.5 3.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin OsmC PF02566.14 ETO29564.1 - 0.11 12.7 1.0 0.18 11.9 0.6 1.4 1 1 0 1 1 1 0 OsmC-like protein DUF740 PF05340.7 ETO29564.1 - 0.32 9.3 6.6 0.37 9.0 4.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF740) PvlArgDC PF01862.11 ETO29564.1 - 0.44 10.1 3.3 0.55 9.8 2.3 1.1 1 0 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) A_deaminase PF00962.17 ETO29565.1 - 5.9e-47 160.1 1.2 1.7e-37 129.0 0.3 2.7 2 1 0 2 2 2 2 Adenosine/AMP deaminase A_deaminase PF00962.17 ETO29566.1 - 2.3e-11 43.1 0.0 1.2e-10 40.7 0.0 2.0 1 1 0 1 1 1 1 Adenosine/AMP deaminase DUF4131 PF13567.1 ETO29567.1 - 0.019 14.3 1.7 0.097 12.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF2252 PF10009.4 ETO29567.1 - 0.27 10.0 5.1 0.38 9.6 3.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Neur_chan_memb PF02932.11 ETO29567.1 - 9.1 6.0 8.6 17 5.1 5.9 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Abhydrolase_5 PF12695.2 ETO29568.1 - 3.5e-11 43.0 0.0 1.3e-10 41.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETO29568.1 - 1.2e-05 25.2 0.0 2.4e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 ETO29568.1 - 0.00015 21.2 0.0 0.00016 21.1 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 ETO29568.1 - 0.00024 20.7 0.0 0.00029 20.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.3 ETO29568.1 - 0.0014 18.0 0.0 0.0018 17.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.15 ETO29568.1 - 0.0015 18.1 0.0 0.0028 17.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETO29568.1 - 0.0019 17.4 0.0 0.0022 17.2 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 ETO29568.1 - 0.0059 15.8 0.0 0.0071 15.6 0.0 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase AXE1 PF05448.7 ETO29568.1 - 0.06 11.8 0.0 0.071 11.5 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) UPF0227 PF05728.7 ETO29568.1 - 0.13 11.9 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Shisa PF13908.1 ETO29569.1 - 0.0025 18.0 1.2 0.0025 18.0 0.8 3.5 2 1 2 4 4 4 1 Wnt and FGF inhibitory regulator Mucin PF01456.12 ETO29569.1 - 0.042 13.6 39.3 0.094 12.4 27.2 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein PEHE PF15275.1 ETO29569.1 - 0.71 10.3 14.1 0.026 14.9 4.5 2.3 2 0 0 2 2 2 0 PEHE domain DUF2157 PF09925.4 ETO29569.1 - 0.88 9.1 8.6 0.7 9.4 2.9 2.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) Wyosine_form PF08608.7 ETO29570.1 - 0.002 18.2 0.4 0.01 15.8 0.1 2.3 2 1 1 3 3 3 1 Wyosine base formation PTR2 PF00854.16 ETO29573.1 - 4.7e-48 163.8 0.0 6.5e-47 160.0 0.0 2.1 1 1 1 2 2 2 2 POT family MFS_1 PF07690.11 ETO29573.1 - 6.8e-09 34.8 17.9 0.00047 18.9 0.0 3.9 3 1 0 3 3 3 3 Major Facilitator Superfamily XRN_N PF03159.13 ETO29575.1 - 1.1e-93 313.0 2.9 4.8e-54 183.2 2.0 2.5 2 1 0 2 2 2 2 XRN 5'-3' exonuclease N-terminus Methyltransf_12 PF08242.7 ETO29575.1 - 0.00023 21.5 0.1 0.00087 19.7 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain zf-CCHC PF00098.18 ETO29575.1 - 0.012 15.5 1.3 0.024 14.5 0.9 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF2975 PF11188.3 ETO29575.1 - 0.048 13.3 4.5 0.15 11.7 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Reticulon PF02453.12 ETO29575.1 - 0.31 10.6 5.4 0.17 11.4 0.9 2.1 2 0 0 2 2 2 0 Reticulon DNA_pol3_alpha PF07733.7 ETO29578.1 - 0.034 12.5 0.6 0.047 12.1 0.4 1.1 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha subunit SR-25 PF10500.4 ETO29579.1 - 3.6 7.0 13.8 0.038 13.4 1.5 2.6 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF3271 PF11675.3 ETO29580.1 - 0.01 14.9 0.7 0.015 14.4 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3271) CENP-F_leu_zip PF10473.4 ETO29580.1 - 0.02 14.7 1.6 0.02 14.7 1.1 1.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Flu_PB1 PF00602.12 ETO29580.1 - 0.062 11.0 3.4 0.069 10.8 2.4 1.0 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB1 UPF0227 PF05728.7 ETO29580.1 - 0.074 12.7 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Lge1 PF11488.3 ETO29580.1 - 0.31 11.2 2.5 0.22 11.7 0.3 1.8 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 Mod_r PF07200.8 ETO29580.1 - 1.1 9.1 8.4 0.35 10.7 3.3 1.8 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein LETM1 PF07766.8 ETO29581.1 - 0.0048 15.9 1.4 0.0048 15.9 1.0 2.3 2 1 0 2 2 2 1 LETM1-like protein TFIIA PF03153.8 ETO29581.1 - 5.2 6.8 36.8 7.5 6.3 25.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Apis_Csd PF11671.3 ETO29581.1 - 6 6.6 8.9 1.3 8.8 3.2 2.0 2 0 0 2 2 2 0 Complementary sex determiner protein Sad1_UNC PF07738.8 ETO29582.1 - 1.3e-18 67.1 4.9 4.7e-13 49.0 0.1 2.7 1 1 1 2 2 2 2 Sad1 / UNC-like C-terminal DUF3923 PF13061.1 ETO29582.1 - 0.013 15.3 1.1 0.025 14.4 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3923) DUF1635 PF07795.6 ETO29582.1 - 2.3 7.5 13.6 1.3 8.3 5.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) TSA PF03249.8 ETO29582.1 - 3.8 5.9 9.2 5.9 5.3 6.4 1.3 1 0 0 1 1 1 0 Type specific antigen TPR_11 PF13414.1 ETO29583.1 - 8.7e-18 63.7 26.1 2.1e-05 24.0 1.9 5.7 6 0 0 6 6 6 4 TPR repeat TPR_2 PF07719.12 ETO29583.1 - 5.4e-12 44.6 27.5 0.24 11.4 0.1 7.8 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.1 ETO29583.1 - 1.5e-07 31.2 22.2 0.023 14.6 0.6 6.5 5 2 3 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 ETO29583.1 - 5.2e-07 28.9 23.5 0.0014 18.2 0.0 7.8 9 0 0 9 9 9 3 Tetratricopeptide repeat Apc3 PF12895.2 ETO29583.1 - 4.5e-06 26.6 30.1 0.015 15.3 5.7 4.3 3 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 ETO29583.1 - 5.1e-06 26.6 0.0 2.2 9.1 0.0 5.3 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO29583.1 - 1.8e-05 25.0 0.4 2 8.8 0.0 4.6 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO29583.1 - 0.001 18.5 31.5 0.1 12.2 0.0 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO29583.1 - 0.0053 16.8 14.5 0.6 10.4 0.0 6.2 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETO29583.1 - 0.044 13.6 0.0 10 6.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 ETO29583.1 - 0.073 13.0 1.8 4.1 7.4 0.0 3.6 5 0 0 5 5 5 0 Tetratricopeptide repeat CobT PF06213.7 ETO29584.1 - 5.4e-05 22.4 12.5 5.4e-05 22.4 8.6 2.6 2 0 0 2 2 2 1 Cobalamin biosynthesis protein CobT Prothymosin PF03247.9 ETO29584.1 - 0.0046 17.0 31.1 0.0046 17.0 21.5 3.8 3 0 0 3 3 3 2 Prothymosin/parathymosin family Syntaxin-6_N PF09177.6 ETO29586.1 - 0.72 10.2 20.6 0.24 11.8 5.3 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Cast PF10174.4 ETO29586.1 - 1 7.3 36.6 0.046 11.7 15.9 2.0 1 1 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone Pox_A_type_inc PF04508.7 ETO29586.1 - 1 9.2 6.3 3.4 7.7 0.3 3.9 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat MscS_porin PF12795.2 ETO29586.1 - 2.4 7.4 44.5 0.89 8.8 24.5 2.0 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain PhosphMutase PF10143.4 ETO29586.1 - 3 7.4 5.1 1.9 8.1 2.1 1.6 1 1 0 1 1 1 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Reo_sigmaC PF04582.7 ETO29586.1 - 6.4 5.8 9.4 2 7.4 3.5 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein PLRV_ORF5 PF01690.12 ETO29586.1 - 8 5.4 12.6 8.9 5.3 8.7 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Voltage_CLC PF00654.15 ETO29587.1 - 3.1e-19 69.2 9.5 5.6e-19 68.3 6.6 1.6 1 1 0 1 1 1 1 Voltage gated chloride channel Big_5 PF13205.1 ETO29588.1 - 0.0087 16.6 0.0 0.014 16.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial Ig-like domain CDC45 PF02724.9 ETO29589.1 - 9.1 4.1 29.3 1.1 7.2 11.1 2.1 2 0 0 2 2 2 0 CDC45-like protein Daxx PF03344.10 ETO29590.1 - 0.0014 17.2 18.2 0.0015 17.1 12.6 1.0 1 0 0 1 1 1 1 Daxx Family DUF3485 PF11984.3 ETO29590.1 - 0.049 12.7 0.2 0.053 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3485) DUF2457 PF10446.4 ETO29590.1 - 0.082 11.6 13.0 0.091 11.4 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) YL1 PF05764.8 ETO29590.1 - 0.094 12.3 15.3 0.11 12.1 10.6 1.2 1 0 0 1 1 1 0 YL1 nuclear protein IFT57 PF10498.4 ETO29590.1 - 0.17 10.6 9.2 0.17 10.5 6.4 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 TFIIF_alpha PF05793.7 ETO29590.1 - 0.49 8.6 19.1 0.51 8.6 13.3 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) HSP90 PF00183.13 ETO29590.1 - 0.53 8.6 8.7 0.5 8.6 6.1 1.2 1 0 0 1 1 1 0 Hsp90 protein DUF572 PF04502.8 ETO29590.1 - 3 6.9 18.3 3.6 6.7 12.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Merozoite_SPAM PF07133.6 ETO29590.1 - 3.3 7.5 17.6 4.5 7.1 12.2 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Sigma70_ner PF04546.8 ETO29590.1 - 3.4 7.2 14.8 5.7 6.4 10.3 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Pox_RNA_Pol_19 PF05320.7 ETO29590.1 - 4.7 6.9 15.5 3 7.5 9.8 1.4 1 1 1 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Mito_carr PF00153.22 ETO29591.1 - 7e-38 128.2 3.2 6.5e-14 51.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2207 PF09972.4 ETO29592.1 - 0.084 11.4 4.1 0.12 10.9 2.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1360 PF07098.6 ETO29592.1 - 0.088 12.5 0.2 0.088 12.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1360) KbaA PF14089.1 ETO29592.1 - 1.1 8.7 9.7 3.2 7.2 3.5 2.2 2 0 0 2 2 2 0 KinB-signalling pathway activation in sporulation SdpI PF13630.1 ETO29592.1 - 7.6 6.3 9.1 0.89 9.3 3.3 1.7 2 0 0 2 2 2 0 SdpI/YhfL protein family E7 PF00527.13 ETO29593.1 - 0.1 12.7 0.3 0.3 11.2 0.0 1.9 2 0 0 2 2 2 0 E7 protein, Early protein Eapp_C PF10238.4 ETO29593.1 - 0.95 9.3 30.5 0.11 12.3 3.4 3.6 4 0 0 4 4 4 0 E2F-associated phosphoprotein UPF0546 PF10639.4 ETO29594.1 - 1.4e-28 98.9 6.1 3.3e-28 97.7 4.2 1.6 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 EmrE PF13536.1 ETO29594.1 - 0.011 15.9 7.6 0.011 15.9 5.3 2.0 2 0 0 2 2 2 0 Multidrug resistance efflux transporter EamA PF00892.15 ETO29594.1 - 1.5 8.8 15.8 0.13 12.3 5.2 2.5 3 0 0 3 3 3 0 EamA-like transporter family STT3 PF02516.9 ETO29595.1 - 2e-40 139.2 39.9 1e-37 130.2 26.0 2.4 2 1 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit NosD PF05048.8 ETO29597.1 - 0.0072 15.4 0.5 0.0079 15.3 0.4 1.1 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) DUF3504 PF12012.3 ETO29597.1 - 0.081 12.6 6.4 0.098 12.4 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) Bud13 PF09736.4 ETO29597.1 - 2.9 8.1 14.2 3.8 7.7 9.8 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex PMSI1 PF15322.1 ETO29597.1 - 3.9 6.4 6.6 4.2 6.3 4.6 1.0 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative GAGA_bind PF06217.7 ETO29597.1 - 4.2 7.2 10.1 4.6 7.1 7.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family GHL15 PF14885.1 ETO29598.1 - 0.05 13.8 0.0 0.092 12.9 0.0 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 PP2C PF00481.16 ETO29600.1 - 0.044 13.1 0.0 0.1 11.9 0.0 1.6 1 1 0 1 1 1 0 Protein phosphatase 2C DUF2573 PF10835.3 ETO29601.1 - 0.012 15.6 2.7 0.38 10.8 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2573) DUF3395 PF11875.3 ETO29601.1 - 0.013 15.1 4.2 0.024 14.2 2.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) MtrB PF05440.7 ETO29601.1 - 0.22 11.5 1.0 0.83 9.7 0.1 2.4 2 1 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B Nanovirus_C8 PF05629.6 ETO29601.1 - 0.25 11.1 2.8 0.25 11.1 0.5 2.0 1 1 0 1 1 1 0 Nanovirus component 8 (C8) protein AAA_13 PF13166.1 ETO29601.1 - 0.32 9.4 18.0 0.47 8.8 6.3 2.0 2 0 0 2 2 2 0 AAA domain Prefoldin PF02996.12 ETO29601.1 - 0.35 10.5 16.6 0.092 12.3 0.6 3.7 3 1 0 3 3 3 0 Prefoldin subunit Telomerase_RBD PF12009.3 ETO29601.1 - 1.1 9.1 12.0 0.16 11.8 1.9 2.7 3 0 0 3 3 3 0 Telomerase ribonucleoprotein complex - RNA binding domain Reo_sigmaC PF04582.7 ETO29601.1 - 1.2 8.1 7.2 2 7.5 3.4 2.3 2 1 0 2 2 2 0 Reovirus sigma C capsid protein Not3 PF04065.10 ETO29601.1 - 2.7 7.1 23.1 0.063 12.5 6.3 2.9 3 0 0 3 3 3 0 Not1 N-terminal domain, CCR4-Not complex component MCPsignal PF00015.16 ETO29601.1 - 4.1 6.8 14.0 4.3 6.8 4.4 3.2 3 1 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Rota_NS6 PF04866.7 ETO29601.1 - 7 6.7 11.3 0.74 9.8 0.3 3.8 3 1 1 4 4 4 0 Rotavirus non-structural protein 6 ABC_tran PF00005.22 ETO29602.1 - 8.8e-12 45.4 0.0 1.6e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 ETO29602.1 - 5.8e-06 25.6 0.2 7.2e-06 25.3 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 ETO29602.1 - 0.0063 16.4 0.9 0.09 12.6 0.6 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 ETO29602.1 - 0.11 12.3 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 ETO29603.1 - 7.7e-15 55.3 0.0 3.9e-14 53.1 0.0 2.1 1 1 0 1 1 1 1 ABC transporter DUF258 PF03193.11 ETO29603.1 - 0.004 16.3 0.0 0.0062 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 ETO29603.1 - 0.0055 16.1 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 ETO29603.1 - 0.0084 16.1 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ABC_membrane PF00664.18 ETO29603.1 - 0.025 13.9 6.2 0.044 13.1 4.3 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region AAA_17 PF13207.1 ETO29603.1 - 0.055 14.2 0.0 0.13 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 ETO29603.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 ETO29603.1 - 0.11 11.9 0.1 0.26 10.6 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain AAA_25 PF13481.1 ETO29603.1 - 0.14 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain RhoGAP PF00620.22 ETO29604.1 - 8.4e-09 35.2 0.0 1.4e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain AA_permease_2 PF13520.1 ETO29605.1 - 5.8e-48 163.4 40.5 7.2e-48 163.1 28.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETO29605.1 - 1.2e-32 112.9 37.2 1.4e-32 112.6 25.8 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2244 PF10003.4 ETO29606.1 - 0.095 12.0 0.3 1 8.7 0.0 2.6 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Phage_HK97_TLTM PF06120.6 ETO29607.1 - 0.057 12.7 0.1 0.09 12.0 0.0 1.4 1 1 0 1 1 1 0 Tail length tape measure protein F-box-like PF12937.2 ETO29608.1 - 2.5e-05 23.8 0.3 2.5e-05 23.8 0.2 2.3 2 0 0 2 2 2 1 F-box-like DUF3452 PF11934.3 ETO29609.1 - 0.1 11.9 0.8 1 8.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) SPT6_acidic PF14632.1 ETO29609.1 - 1.8 8.8 7.0 0.25 11.5 2.1 1.6 2 0 0 2 2 2 0 Acidic N-terminal SPT6 EF-hand_7 PF13499.1 ETO29610.1 - 1.4e-05 25.1 3.6 0.061 13.4 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 ETO29610.1 - 0.0005 19.1 3.9 0.1 11.9 0.0 4.5 5 0 0 5 5 5 1 EF hand EF-hand_8 PF13833.1 ETO29610.1 - 0.0011 18.4 1.3 0.83 9.3 0.1 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO29610.1 - 0.0012 18.4 1.2 0.14 12.1 0.2 3.7 3 1 0 3 3 3 1 EF-hand domain PC_rep PF01851.17 ETO29611.1 - 0.16 12.2 2.4 0.71 10.2 0.0 3.5 3 0 0 3 3 3 0 Proteasome/cyclosome repeat Kelch_1 PF01344.20 ETO29612.1 - 8.8e-09 34.7 5.5 1.1e-05 24.8 0.8 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO29612.1 - 1.6e-08 34.3 3.3 0.00045 20.2 0.2 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO29612.1 - 8.6e-08 31.6 3.6 0.0012 18.5 0.4 4.6 4 1 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 ETO29612.1 - 1.9e-06 27.8 0.2 0.00027 21.0 0.0 3.3 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO29612.1 - 3e-06 26.8 0.4 0.0084 15.8 0.1 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO29612.1 - 4.2e-06 26.5 0.2 0.26 11.2 0.6 4.1 4 0 0 4 4 4 2 Kelch motif SMI1_KNR4 PF09346.5 ETO29612.1 - 0.66 9.9 4.9 0.44 10.5 1.3 2.4 2 2 0 2 2 2 0 SMI1 / KNR4 family (SUKH-1) Aldedh PF00171.17 ETO29615.1 - 3.2e-79 266.4 0.0 3.5e-79 266.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PI3K_rbd PF00794.13 ETO29617.1 - 0.076 12.9 0.5 2.3 8.1 0.0 2.9 3 0 0 3 3 3 0 PI3-kinase family, ras-binding domain DUF1394 PF07159.7 ETO29618.1 - 1.2e-20 73.8 0.7 2.2e-20 72.9 0.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1394) Apt1 PF10351.4 ETO29623.1 - 0.017 14.0 6.9 0.022 13.6 4.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RAM PF15320.1 ETO29623.1 - 0.15 12.3 10.3 1.6 9.0 0.3 2.5 2 0 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein Macoilin PF09726.4 ETO29623.1 - 0.29 9.3 21.9 0.4 8.9 15.2 1.2 1 0 0 1 1 1 0 Transmembrane protein Pex14_N PF04695.8 ETO29623.1 - 2.5 8.1 19.2 1.3 9.0 5.8 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Eapp_C PF10238.4 ETO29623.1 - 4.3 7.2 20.0 0.24 11.2 3.2 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF4614 PF15391.1 ETO29623.1 - 5.1 6.8 12.9 3.5 7.3 6.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) WD40 PF00400.27 ETO29625.1 - 1.2e-11 44.0 8.9 7.1e-08 32.0 0.0 4.4 4 1 0 4 4 4 3 WD domain, G-beta repeat eIF2A PF08662.6 ETO29625.1 - 0.068 12.8 0.1 1.8 8.2 0.0 2.1 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO29625.1 - 0.099 12.3 1.0 0.64 9.7 0.0 2.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 ETO29626.1 - 7.3e-18 63.7 0.6 0.00068 19.4 0.0 4.6 5 0 0 5 5 5 4 WD domain, G-beta repeat PD40 PF07676.7 ETO29626.1 - 0.0096 15.5 0.5 2.9 7.6 0.0 3.0 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat AICARFT_IMPCHas PF01808.13 ETO29626.1 - 0.14 11.2 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 AICARFT/IMPCHase bienzyme WD40 PF00400.27 ETO29627.1 - 6.7e-87 282.5 13.5 1.7e-12 46.7 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO29627.1 - 2.8e-13 50.0 0.1 0.00013 21.7 0.0 3.4 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO29627.1 - 2.8e-07 29.0 7.8 0.024 12.7 0.0 5.3 1 1 4 6 6 6 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO29627.1 - 8e-07 27.6 1.2 0.0041 15.4 0.1 3.7 2 1 2 4 4 4 3 Cytochrome D1 heme domain PD40 PF07676.7 ETO29627.1 - 2.5e-06 26.9 6.0 2.2 8.0 0.0 6.2 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO29627.1 - 0.00013 20.9 8.6 2.4 6.8 0.3 5.0 2 1 2 4 4 4 2 Nup133 N terminal like DUF1258 PF06869.7 ETO29627.1 - 0.00033 19.8 0.7 0.42 9.6 0.0 3.6 2 2 2 4 4 4 2 Protein of unknown function (DUF1258) B_lectin PF01453.19 ETO29627.1 - 0.0018 18.1 0.2 0.024 14.5 0.1 2.6 1 1 3 4 4 4 2 D-mannose binding lectin NodS PF05401.6 ETO29627.1 - 0.0021 17.4 0.5 0.89 8.9 0.0 3.9 4 1 1 5 5 5 1 Nodulation protein S (NodS) Coatomer_WDAD PF04053.9 ETO29627.1 - 0.003 16.4 0.1 0.0068 15.2 0.1 1.5 1 1 0 1 1 1 1 Coatomer WD associated region Resistin PF06954.6 ETO29627.1 - 0.0038 17.4 0.5 43 4.4 0.1 4.0 2 1 2 4 4 4 0 Resistin Mid2 PF04478.7 ETO29627.1 - 0.037 13.4 0.6 6.7 6.1 0.1 3.6 3 1 1 4 4 4 0 Mid2 like cell wall stress sensor DUF3509 PF12021.3 ETO29627.1 - 0.075 12.7 0.0 5.7 6.7 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3509) Proteasome_A_N PF10584.4 ETO29627.1 - 3 7.2 16.6 7.5 5.9 0.0 6.0 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature Endomucin PF07010.7 ETO29628.1 - 0.018 14.3 6.0 0.02 14.2 4.1 1.1 1 0 0 1 1 1 0 Endomucin Pneumo_M2 PF07380.6 ETO29628.1 - 0.04 13.9 0.4 0.094 12.7 0.3 1.6 1 0 0 1 1 1 0 Pneumovirus M2 protein Peptidase_C37 PF05416.7 ETO29628.1 - 0.058 11.6 0.3 0.061 11.6 0.2 1.0 1 0 0 1 1 1 0 Southampton virus-type processing peptidase YgbB PF02542.11 ETO29628.1 - 0.089 12.6 4.6 0.12 12.1 3.2 1.2 1 0 0 1 1 1 0 YgbB family LAGLIDADG_3 PF14528.1 ETO29628.1 - 0.12 12.6 1.8 0.26 11.5 1.2 1.6 1 1 0 1 1 1 0 LAGLIDADG-like domain Xpo1 PF08389.7 ETO29628.1 - 0.23 11.3 3.3 0.29 11.0 2.3 1.1 1 0 0 1 1 1 0 Exportin 1-like protein YlbD_coat PF14071.1 ETO29628.1 - 0.34 10.9 4.2 0.43 10.6 2.9 1.2 1 0 0 1 1 1 0 Putative coat protein BPL_N PF09825.4 ETO29628.1 - 1.2 7.8 3.8 1.4 7.6 2.7 1.0 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Ku_C PF03730.9 ETO29628.1 - 5.6 7.5 8.1 2.4 8.7 3.1 2.1 1 1 1 2 2 2 0 Ku70/Ku80 C-terminal arm DUF2228 PF10228.4 ETO29628.1 - 6.9 6.1 8.4 18 4.7 2.8 2.0 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2228) E1-E2_ATPase PF00122.15 ETO29629.1 - 4.7e-49 166.4 5.5 8.9e-49 165.5 1.7 2.6 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 ETO29629.1 - 2.4e-30 106.5 0.0 9.1e-30 104.6 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETO29629.1 - 5.5e-14 52.7 1.0 1.8e-13 51.1 0.7 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 ETO29629.1 - 0.016 14.8 3.0 0.06 12.9 0.0 2.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Baculo_E56 PF04639.7 ETO29629.1 - 0.077 11.6 1.2 0.45 9.1 0.1 2.5 2 0 0 2 2 2 0 Baculoviral E56 protein, specific to ODV envelope APG6 PF04111.7 ETO29630.1 - 0.0032 16.5 24.1 0.0032 16.5 16.7 6.0 1 1 4 6 6 6 3 Autophagy protein Apg6 CCDC155 PF14662.1 ETO29630.1 - 0.007 15.9 10.9 0.007 15.9 7.6 6.4 3 1 4 7 7 7 4 Coiled-coil region of CCDC155 GAS PF13851.1 ETO29630.1 - 0.49 9.5 97.7 0.037 13.2 11.8 6.3 2 2 2 6 6 6 0 Growth-arrest specific micro-tubule binding NLE PF08154.7 ETO29631.1 - 1.9e-13 50.2 0.6 1.9e-13 50.2 0.4 1.6 2 0 0 2 2 2 1 NLE (NUC135) domain UQ_con PF00179.21 ETO29632.1 - 2.3e-23 82.1 2.6 2.8e-15 55.9 0.1 3.2 3 0 0 3 3 3 2 Ubiquitin-conjugating enzyme Mucin PF01456.12 ETO29632.1 - 0.0011 18.7 6.2 0.0011 18.7 4.3 2.0 2 0 0 2 2 2 1 Mucin-like glycoprotein DUF2360 PF10152.4 ETO29634.1 - 2.7e-06 27.7 1.4 4.6e-06 26.9 1.0 1.6 1 1 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) TMEM192 PF14802.1 ETO29634.1 - 0.015 14.1 0.2 0.026 13.4 0.2 1.4 1 0 0 1 1 1 0 TMEM192 family Zip PF02535.17 ETO29634.1 - 0.017 14.1 0.7 0.02 13.9 0.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SlyX PF04102.7 ETO29634.1 - 0.17 12.3 1.8 0.4 11.0 1.2 1.6 1 0 0 1 1 1 0 SlyX Pex14_N PF04695.8 ETO29634.1 - 0.26 11.3 13.0 0.071 13.1 4.2 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF641 PF04859.7 ETO29634.1 - 1.3 8.7 6.2 2.9 7.6 0.3 2.3 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) M PF02370.11 ETO29634.1 - 1.4 9.4 5.4 0.42 11.1 0.9 2.5 2 1 0 2 2 2 0 M protein repeat MSC PF09402.5 ETO29634.1 - 2.3 6.8 7.3 3 6.4 5.1 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain EIIBC-GUT_N PF03612.9 ETO29634.1 - 4.3 6.9 8.8 0.46 10.0 2.2 1.9 1 1 1 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Ndc1_Nup PF09531.5 ETO29634.1 - 6.8 4.9 9.2 7.6 4.8 6.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Osteopontin PF00865.13 ETO29635.1 - 0.28 10.3 5.7 0.41 9.8 4.0 1.2 1 0 0 1 1 1 0 Osteopontin NCA2 PF08637.5 ETO29636.1 - 3.9e-05 22.6 0.1 4.6e-05 22.4 0.1 1.0 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Ser_hydrolase PF06821.8 ETO29636.1 - 0.051 13.1 0.3 0.085 12.4 0.1 1.5 1 1 0 1 1 1 0 Serine hydrolase MRAP PF15183.1 ETO29636.1 - 0.11 12.1 0.1 0.28 10.7 0.0 1.7 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family Tubulin PF00091.20 ETO29637.1 - 3.2e-16 59.8 0.0 5.8e-16 58.9 0.0 1.5 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO29637.1 - 3.5e-07 30.3 0.5 9e-07 28.9 0.3 1.8 1 0 0 1 1 1 1 Tubulin C-terminal domain DUF1462 PF07315.6 ETO29637.1 - 0.0016 18.3 0.6 0.025 14.5 0.1 3.0 4 0 0 4 4 4 1 Protein of unknown function (DUF1462) Zip PF02535.17 ETO29638.1 - 0.063 12.2 0.1 0.063 12.2 0.0 2.6 1 1 1 3 3 3 0 ZIP Zinc transporter Innate_immun PF12782.2 ETO29638.1 - 0.47 9.6 22.3 0.74 8.9 15.4 1.2 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Ank_2 PF12796.2 ETO29639.1 - 4.8e-10 39.6 0.0 1.4e-09 38.1 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO29639.1 - 8.3e-09 35.4 0.6 4.6e-07 29.8 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO29639.1 - 3.9e-08 33.6 0.1 4.9e-07 30.0 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 ETO29639.1 - 2.3e-07 30.2 0.1 0.0019 17.8 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 ETO29639.1 - 1.7e-06 27.6 0.1 0.12 12.7 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Arm PF00514.18 ETO29639.1 - 0.081 12.7 10.5 1.2 9.0 0.2 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat zf-TRAF PF02176.13 ETO29640.1 - 2.9e-05 24.3 5.6 2.9e-05 24.3 3.9 2.1 2 0 0 2 2 2 1 TRAF-type zinc finger COX5A PF02284.11 ETO29641.1 - 0.14 12.0 0.3 0.14 12.0 0.2 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Va Borrelia_P83 PF05262.6 ETO29641.1 - 0.27 9.4 3.5 0.32 9.2 2.5 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein CCDC155 PF14662.1 ETO29642.1 - 0.00074 19.1 3.8 0.00074 19.1 2.7 3.3 3 0 0 3 3 3 1 Coiled-coil region of CCDC155 IL6 PF00489.12 ETO29642.1 - 0.021 14.4 3.0 3.4 7.2 0.1 2.4 2 0 0 2 2 2 0 Interleukin-6/G-CSF/MGF family Syntaxin-6_N PF09177.6 ETO29642.1 - 0.13 12.7 9.7 0.77 10.2 0.4 3.5 3 0 0 3 3 3 0 Syntaxin 6, N-terminal WTX PF09422.5 ETO29642.1 - 0.24 10.3 0.1 0.24 10.3 0.0 2.1 2 1 1 3 3 3 0 WTX protein MerR-DNA-bind PF09278.6 ETO29642.1 - 0.32 11.4 10.0 7.5 7.0 0.5 3.5 3 0 0 3 3 3 0 MerR, DNA binding DUF1664 PF07889.7 ETO29642.1 - 0.39 10.5 6.0 2.5 7.9 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Med10 PF09748.4 ETO29642.1 - 0.46 10.3 7.5 0.39 10.5 0.5 3.0 3 0 0 3 3 3 0 Transcription factor subunit Med10 of Mediator complex DivIC PF04977.10 ETO29642.1 - 0.54 9.7 19.5 0.38 10.2 1.6 4.1 4 0 0 4 4 4 0 Septum formation initiator Prefoldin PF02996.12 ETO29642.1 - 0.94 9.1 9.7 1.3 8.7 0.2 3.4 3 0 0 3 3 3 0 Prefoldin subunit TBPIP PF07106.8 ETO29642.1 - 1.2 8.6 20.1 0.27 10.7 1.1 3.1 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CorA PF01544.13 ETO29642.1 - 1.4 7.8 6.8 0.23 10.4 0.1 2.5 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein H-kinase_dim PF02895.9 ETO29642.1 - 1.5 9.2 6.2 22 5.4 0.3 3.3 3 0 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain Bap31 PF05529.7 ETO29642.1 - 2.5 7.4 13.0 1.2 8.5 0.7 2.9 3 0 0 3 3 3 0 B-cell receptor-associated protein 31-like IncA PF04156.9 ETO29642.1 - 2.9 7.4 20.3 2.4 7.7 1.5 3.3 3 0 0 3 3 3 0 IncA protein DUF4446 PF14584.1 ETO29642.1 - 3 7.6 11.2 0.53 10.0 0.8 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) FliD_C PF07195.7 ETO29642.1 - 8.1 5.6 11.7 3.4 6.8 0.3 2.6 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 C-terminus DUF2664 PF10867.3 ETO29642.1 - 8.8 7.0 10.6 0.37 11.4 0.3 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2664) FRD2 PF03197.8 ETO29643.1 - 0.065 13.7 0.3 0.18 12.3 0.2 1.7 1 0 0 1 1 1 0 Bacteriophage FRD2 protein FliD_N PF02465.13 ETO29643.1 - 0.6 10.5 3.9 0.41 11.0 0.6 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus WD40 PF00400.27 ETO29644.1 - 2.2e-43 144.6 10.6 1.7e-10 40.3 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 ETO29644.1 - 9.9e-11 41.7 0.2 0.0026 17.4 0.0 4.6 1 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO29644.1 - 3e-06 26.7 2.0 6.1 6.6 0.0 5.5 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Kelch_5 PF13854.1 ETO29644.1 - 4.4e-05 23.3 0.4 0.1 12.6 0.1 3.6 3 0 0 3 3 3 2 Kelch motif Nucleoporin_N PF08801.6 ETO29644.1 - 0.00028 19.7 4.2 0.1 11.3 0.1 3.4 1 1 2 3 3 3 3 Nup133 N terminal like Kelch_1 PF01344.20 ETO29644.1 - 0.00036 20.0 2.6 0.082 12.4 0.2 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO29644.1 - 0.00047 20.2 1.7 0.28 11.4 0.1 3.4 3 0 0 3 3 3 1 Kelch motif PQQ_2 PF13360.1 ETO29644.1 - 0.00068 19.1 0.0 1.2 8.5 0.0 2.2 1 1 1 2 2 2 2 PQQ-like domain Cytochrom_D1 PF02239.11 ETO29644.1 - 0.0018 16.6 1.1 0.31 9.2 0.1 2.5 1 1 2 3 3 3 2 Cytochrome D1 heme domain Kelch_2 PF07646.10 ETO29644.1 - 0.012 15.3 0.6 1.9 8.4 0.1 3.7 3 0 0 3 3 3 0 Kelch motif Nup160 PF11715.3 ETO29644.1 - 0.018 13.2 0.1 2.2 6.3 0.0 3.3 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Proteasome_A_N PF10584.4 ETO29644.1 - 0.15 11.4 0.0 10 5.5 0.0 2.9 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 ETO29645.1 - 1.7e-123 398.5 49.1 1.6e-11 43.6 0.1 15.9 15 0 0 15 15 15 15 WD domain, G-beta repeat NACHT PF05729.7 ETO29645.1 - 3.3e-10 39.8 0.0 6.3e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETO29645.1 - 5.9e-06 26.4 0.1 2.4e-05 24.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETO29645.1 - 6.7e-06 26.4 0.2 0.00016 21.9 0.0 3.4 1 1 1 2 2 2 1 AAA domain Pentapeptide PF00805.17 ETO29645.1 - 3.2e-05 23.0 1.5 0.0001 21.4 1.0 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) AAA_17 PF13207.1 ETO29645.1 - 0.00061 20.6 0.0 0.0039 18.0 0.0 2.5 1 0 0 1 1 1 1 AAA domain Pentapeptide_4 PF13599.1 ETO29645.1 - 0.0031 17.2 0.3 0.0089 15.8 0.2 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) UPF0079 PF02367.12 ETO29645.1 - 0.0059 16.2 0.0 0.033 13.8 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Pentapeptide_3 PF13576.1 ETO29645.1 - 0.0081 16.0 0.1 0.024 14.5 0.1 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) ABC_tran PF00005.22 ETO29645.1 - 0.026 14.8 0.8 0.21 11.8 0.0 3.0 3 0 0 3 3 3 0 ABC transporter AAA_5 PF07728.9 ETO29645.1 - 0.027 14.2 0.0 0.23 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 ETO29645.1 - 0.055 13.3 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain PD40 PF07676.7 ETO29645.1 - 0.21 11.3 15.4 19 5.0 0.1 7.0 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 ETO29646.1 - 1.1e-79 259.7 19.3 9.2e-12 44.3 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO29646.1 - 1.2e-08 33.6 4.0 0.062 11.4 0.0 4.7 1 1 2 4 4 4 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO29646.1 - 2e-06 27.4 0.6 0.0021 17.5 0.1 3.0 1 1 1 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 ETO29646.1 - 7.7e-06 24.9 12.8 0.16 10.6 0.3 5.2 1 1 3 4 4 4 3 Nup133 N terminal like Esterase_phd PF10503.4 ETO29646.1 - 0.05 12.8 0.0 0.083 12.1 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Resistin PF06954.6 ETO29646.1 - 0.051 13.8 0.2 18 5.7 0.0 3.6 3 1 1 4 4 4 0 Resistin USP7_C2 PF14533.1 ETO29646.1 - 0.069 12.5 0.0 9 5.6 0.0 3.2 3 1 1 4 4 4 0 Ubiquitin-specific protease C-terminal PA14 PF07691.7 ETO29646.1 - 0.11 12.1 0.0 0.46 10.1 0.0 2.1 1 1 0 1 1 1 0 PA14 domain PD40 PF07676.7 ETO29646.1 - 0.11 12.2 1.7 16 5.3 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat MFS_1 PF07690.11 ETO29647.1 - 1.1e-06 27.5 0.1 1.2e-06 27.4 0.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily BT1 PF03092.11 ETO29647.1 - 0.0038 16.0 0.1 0.0059 15.3 0.1 1.3 1 1 0 1 1 1 1 BT1 family PIRT PF15099.1 ETO29647.1 - 0.0081 15.3 0.2 0.0081 15.3 0.1 1.8 2 1 0 2 2 2 1 Phosphoinositide-interacting protein family Bacteriocin_IId PF09221.5 ETO29647.1 - 0.45 10.4 2.6 32 4.5 0.1 2.8 3 0 0 3 3 3 0 Bacteriocin class IId cyclical uberolysin-like DIOX_N PF14226.1 ETO29648.1 - 5.2e-20 72.1 0.3 2.4e-19 69.9 0.2 2.0 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETO29648.1 - 7.1e-14 51.9 0.1 1.6e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.2 ETO29649.1 - 3.4e-31 107.4 0.0 3.9e-11 43.1 0.0 3.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETO29649.1 - 9.1e-30 100.9 0.1 8e-08 31.7 0.0 6.9 6 1 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 ETO29649.1 - 4.9e-28 94.3 0.3 7e-07 28.8 0.0 8.1 8 1 1 9 9 9 4 Ankyrin repeat Ank_4 PF13637.1 ETO29649.1 - 8.6e-27 93.0 0.0 5.2e-07 30.0 0.0 5.5 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO29649.1 - 4.5e-25 87.1 0.1 0.00029 20.9 0.0 6.2 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Pyr_redox_2 PF07992.9 ETO29650.1 - 1.4e-05 25.0 0.0 4.4e-05 23.4 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF2217 PF10265.4 ETO29652.1 - 0.33 9.6 12.3 0.41 9.3 8.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Hid1 PF12722.2 ETO29652.1 - 4.9 4.7 15.5 8.1 3.9 10.8 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1777 PF08648.7 ETO29652.1 - 8.3 6.0 37.3 0.1 12.2 20.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Utp14 PF04615.8 ETO29653.1 - 0.29 9.2 48.6 0.41 8.7 23.2 2.1 2 0 0 2 2 2 0 Utp14 protein DUF3530 PF12048.3 ETO29653.1 - 0.43 9.5 5.5 1 8.2 3.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DUF1180 PF06679.7 ETO29653.1 - 0.7 9.7 2.9 4.9 7.0 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Nucleoporin_N PF08801.6 ETO29654.1 - 2.5e-21 75.9 4.4 2.7e-21 75.8 3.1 1.0 1 0 0 1 1 1 1 Nup133 N terminal like PLA1 PF02253.10 ETO29654.1 - 0.044 13.2 0.1 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Phospholipase A1 PUA PF01472.15 ETO29654.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 PUA domain DUF463 PF04317.7 ETO29654.1 - 0.12 10.9 0.1 4.6 5.7 0.0 2.1 2 0 0 2 2 2 0 YcjX-like family, DUF463 FBA_2 PF07735.12 ETO29656.1 - 0.025 14.4 0.2 0.063 13.1 0.1 1.7 1 0 0 1 1 1 0 F-box associated G-alpha PF00503.15 ETO29657.1 - 5e-21 74.8 0.1 6.7e-21 74.4 0.1 1.1 1 0 0 1 1 1 1 G-protein alpha subunit RimK PF08443.6 ETO29658.1 - 1.1e-29 103.2 0.0 1.4e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 RimK-like ATP-grasp domain GSH-S_ATP PF02955.11 ETO29658.1 - 4.6e-13 48.6 0.0 6.1e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_4 PF13535.1 ETO29658.1 - 2.4e-05 24.1 0.0 3.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 ETO29658.1 - 0.0011 18.9 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 ETO29658.1 - 0.0064 15.7 0.0 0.0087 15.3 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Pkinase PF00069.20 ETO29659.1 - 3.4e-35 121.4 1.9 6.3e-35 120.5 1.3 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO29659.1 - 1.7e-23 83.0 0.5 2.5e-23 82.4 0.3 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO29659.1 - 4.2e-06 25.9 0.3 8e-06 25.0 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 ETO29659.1 - 0.028 13.7 0.1 0.043 13.1 0.0 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Sporozoite_P67 PF05642.6 ETO29659.1 - 0.037 11.9 9.4 0.051 11.4 6.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen APH PF01636.18 ETO29659.1 - 0.073 12.7 0.0 0.22 11.2 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family CDC45 PF02724.9 ETO29659.1 - 0.08 10.9 12.5 0.099 10.6 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 ETO29659.1 - 0.39 8.3 7.6 0.46 8.1 5.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Macoilin PF09726.4 ETO29659.1 - 1.5 7.0 16.1 2.2 6.4 11.2 1.2 1 0 0 1 1 1 0 Transmembrane protein NOA36 PF06524.7 ETO29659.1 - 2.5 7.2 14.1 3.8 6.6 9.8 1.3 1 0 0 1 1 1 0 NOA36 protein YMF19 PF02326.10 ETO29659.1 - 3 8.4 9.6 5.2 7.7 0.2 3.5 3 1 0 3 3 3 0 Plant ATP synthase F0 WD40 PF00400.27 ETO29660.1 - 2.5e-77 252.2 6.7 1.6e-12 46.7 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO29660.1 - 2.8e-06 25.7 1.2 0.0024 16.0 0.1 3.2 1 1 2 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO29660.1 - 6.6e-05 22.4 1.0 0.0013 18.2 0.6 2.8 1 1 0 1 1 1 1 PQQ-like domain PD40 PF07676.7 ETO29660.1 - 0.00042 19.9 6.3 5.9 6.6 0.0 5.9 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 ETO29660.1 - 0.00072 18.2 0.3 4.8 5.6 0.0 3.7 1 1 3 4 4 4 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Me-amine-dh_H PF06433.6 ETO29660.1 - 0.0041 15.8 0.0 0.29 9.7 0.0 3.1 2 1 1 4 4 4 2 Methylamine dehydrogenase heavy chain (MADH) Mid2 PF04478.7 ETO29660.1 - 0.045 13.1 1.6 11 5.3 0.0 3.5 3 2 1 4 4 4 0 Mid2 like cell wall stress sensor DUF1797 PF08796.5 ETO29660.1 - 0.097 12.5 0.0 27 4.7 0.0 3.8 3 2 2 5 5 5 0 Protein of unknown function (DUF1797) Proteasome_A_N PF10584.4 ETO29660.1 - 0.64 9.3 3.8 60 3.0 0.0 4.7 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature N-SET PF11764.3 ETO29661.1 - 0.0042 17.0 0.3 0.0058 16.5 0.2 1.2 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component N Kelch_5 PF13854.1 ETO29662.1 - 6.7e-10 38.7 7.5 0.0009 19.1 0.0 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 ETO29662.1 - 2.8e-09 36.3 12.4 7.1e-05 22.2 0.0 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 ETO29662.1 - 6.5e-09 35.5 15.6 0.002 18.2 0.0 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.1 ETO29662.1 - 1.6e-06 28.0 15.6 0.00013 22.0 0.0 5.7 6 0 0 6 6 5 2 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO29662.1 - 7.3e-06 25.6 11.2 0.02 14.6 0.0 5.8 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO29662.1 - 1.2e-05 24.8 5.7 0.002 17.7 0.0 4.9 5 0 0 5 5 5 1 Kelch motif PT PF04886.7 ETO29662.1 - 0.00037 19.7 13.6 0.00099 18.3 9.4 1.7 1 0 0 1 1 1 1 PT repeat DUF1510 PF07423.6 ETO29662.1 - 0.0024 17.2 0.8 0.0049 16.2 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) 7TM_GPCR_Srw PF10324.4 ETO29662.1 - 0.014 14.5 0.2 0.034 13.2 0.1 1.6 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw DUF1443 PF07280.6 ETO29662.1 - 0.026 14.0 1.5 0.062 12.8 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1443) IncA PF04156.9 ETO29662.1 - 0.054 13.0 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 IncA protein AAA PF00004.24 ETO29663.1 - 6.3e-92 304.6 0.0 4.3e-48 162.8 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 ETO29663.1 - 2.3e-14 52.9 0.0 2e-07 30.2 0.0 2.8 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 ETO29663.1 - 7e-13 48.9 7.7 1.1e-05 25.4 0.7 4.1 2 2 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.9 ETO29663.1 - 3.3e-12 46.6 0.0 0.00014 21.8 0.0 3.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 ETO29663.1 - 1.7e-11 44.1 1.7 7.1e-05 22.7 0.0 3.4 4 0 0 4 4 3 2 AAA domain IstB_IS21 PF01695.12 ETO29663.1 - 3.1e-11 43.0 0.0 8.3e-05 22.0 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_17 PF13207.1 ETO29663.1 - 4.6e-11 43.5 2.9 0.00026 21.8 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_22 PF13401.1 ETO29663.1 - 4.7e-11 42.9 4.5 0.0016 18.5 0.1 5.6 4 2 0 4 4 4 2 AAA domain AAA_5 PF07728.9 ETO29663.1 - 1.7e-09 37.4 1.6 0.002 17.8 0.1 4.1 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 ETO29663.1 - 2.1e-09 37.3 0.0 0.0019 18.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 ETO29663.1 - 2.5e-08 33.2 3.3 0.00076 18.6 0.0 3.6 3 1 0 3 3 3 2 Zeta toxin AAA_19 PF13245.1 ETO29663.1 - 1.4e-07 31.1 2.5 0.0039 16.9 0.1 3.1 3 0 0 3 3 3 2 Part of AAA domain Mg_chelatase PF01078.16 ETO29663.1 - 2.6e-07 30.0 0.9 0.023 13.8 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 ETO29663.1 - 4.5e-07 28.9 0.2 0.013 14.2 0.0 2.6 2 1 0 2 2 2 2 TIP49 C-terminus RNA_helicase PF00910.17 ETO29663.1 - 7.2e-07 29.3 0.0 0.011 15.8 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 ETO29663.1 - 1.2e-06 28.6 0.0 0.055 13.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.1 ETO29663.1 - 1.7e-06 28.1 0.4 0.091 12.8 0.0 3.3 4 0 0 4 4 3 2 Sigma-54 interaction domain NACHT PF05729.7 ETO29663.1 - 1.8e-06 27.6 2.8 0.1 12.2 0.0 3.8 3 1 1 4 4 4 2 NACHT domain AAA_25 PF13481.1 ETO29663.1 - 3.8e-06 26.4 8.9 0.4 10.0 0.1 4.5 2 2 1 4 4 4 2 AAA domain AAA_18 PF13238.1 ETO29663.1 - 5.4e-06 26.7 7.5 0.019 15.2 0.0 4.0 4 0 0 4 4 3 2 AAA domain Viral_helicase1 PF01443.13 ETO29663.1 - 9.4e-05 22.0 0.2 0.52 9.8 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase KaiC PF06745.8 ETO29663.1 - 9.6e-05 21.6 0.1 0.58 9.2 0.0 3.5 3 1 1 4 4 4 2 KaiC Sigma54_activat PF00158.21 ETO29663.1 - 0.0001 21.8 0.1 0.22 10.9 0.0 3.1 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_24 PF13479.1 ETO29663.1 - 0.0001 21.9 0.1 0.11 12.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 ETO29663.1 - 0.00017 20.9 0.2 0.4 9.8 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein NB-ARC PF00931.17 ETO29663.1 - 0.00035 19.5 0.1 0.15 10.9 0.0 2.7 2 0 0 2 2 2 1 NB-ARC domain AAA_3 PF07726.6 ETO29663.1 - 0.00092 18.8 0.0 1 8.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 ETO29663.1 - 0.001 18.6 0.1 1 8.9 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 ETO29663.1 - 0.0052 16.2 1.9 6.1 6.1 0.0 3.6 3 0 0 3 3 3 0 AAA-like domain ABC_tran PF00005.22 ETO29663.1 - 0.0057 16.9 10.0 0.24 11.7 0.0 3.7 3 2 0 4 4 2 2 ABC transporter CPT PF07931.7 ETO29663.1 - 0.0078 15.8 0.0 0.8 9.3 0.0 2.5 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein SKI PF01202.17 ETO29663.1 - 0.012 15.4 0.1 2.2 8.1 0.0 2.8 2 0 0 2 2 2 0 Shikimate kinase AAA_29 PF13555.1 ETO29663.1 - 0.017 14.6 0.0 5.3 6.6 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 ETO29663.1 - 0.029 14.0 5.5 0.42 10.2 0.0 4.5 3 2 0 4 4 4 0 Archaeal ATPase Zot PF05707.7 ETO29663.1 - 0.041 13.3 1.6 33 3.8 0.0 4.2 4 0 0 4 4 4 0 Zonular occludens toxin (Zot) DEAD PF00270.24 ETO29663.1 - 0.069 12.6 0.9 17 4.8 0.0 3.9 4 1 1 5 5 4 0 DEAD/DEAH box helicase Presenilin PF01080.12 ETO29665.1 - 2 7.1 6.4 2.4 6.8 4.4 1.1 1 0 0 1 1 1 0 Presenilin zf-TRM13_CCCH PF11722.3 ETO29665.1 - 2.1 7.7 7.5 5 6.5 5.2 1.6 1 0 0 1 1 1 0 CCCH zinc finger in TRM13 protein S1 PF00575.18 ETO29667.1 - 8e-18 64.3 0.0 9e-09 35.3 0.0 2.6 2 0 0 2 2 2 2 S1 RNA binding domain F-box PF00646.28 ETO29667.1 - 0.00011 21.7 0.4 0.00022 20.8 0.3 1.5 1 0 0 1 1 1 1 F-box domain S1_2 PF13509.1 ETO29667.1 - 0.0083 16.0 0.0 3.1 7.7 0.0 3.2 2 1 0 2 2 2 1 S1 domain F-box-like PF12937.2 ETO29667.1 - 0.02 14.5 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 F-box-like SAPS PF04499.10 ETO29667.1 - 1 7.9 8.7 1.3 7.5 6.0 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1162 PF06650.7 ETO29668.1 - 1.8e-10 40.4 0.3 4e-06 26.2 0.0 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF1162) Pex24p PF06398.6 ETO29668.1 - 0.24 10.1 13.5 12 4.5 9.1 2.6 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin zf-TRAF PF02176.13 ETO29669.1 - 1.1e-06 28.9 1.8 1.1e-06 28.9 1.3 2.9 4 0 0 4 4 4 1 TRAF-type zinc finger DUF3671 PF12420.3 ETO29670.1 - 0.049 13.5 1.2 0.093 12.7 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function HAUS5 PF14817.1 ETO29670.1 - 0.055 12.0 2.1 0.069 11.6 1.4 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 WD40 PF00400.27 ETO29671.1 - 4.5e-52 172.1 15.3 1.2e-10 40.7 0.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO29671.1 - 1.2e-10 41.4 0.0 1.4e-06 28.1 0.0 3.0 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO29671.1 - 4.2e-07 29.4 3.6 1.4 8.7 0.1 5.1 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.9 ETO29671.1 - 4.1e-06 25.8 0.1 0.0018 17.1 0.0 2.0 1 1 1 2 2 2 2 Coatomer WD associated region Cytochrom_D1 PF02239.11 ETO29671.1 - 2.6e-05 22.7 0.4 0.036 12.3 0.1 2.8 1 1 1 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.3 ETO29671.1 - 0.00012 20.4 1.2 0.85 7.6 0.1 3.5 2 2 2 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO29671.1 - 0.00034 19.4 5.8 0.68 8.6 0.1 3.9 1 1 2 4 4 4 2 Nup133 N terminal like TFIIIC_delta PF12657.2 ETO29671.1 - 0.0025 17.5 0.7 0.055 13.1 0.0 2.7 2 1 0 2 2 2 1 Transcription factor IIIC subunit delta N-term PQQ_2 PF13360.1 ETO29671.1 - 0.0043 16.5 0.1 0.089 12.2 0.0 2.7 1 1 0 1 1 1 1 PQQ-like domain Proteasome_A_N PF10584.4 ETO29671.1 - 0.015 14.6 3.1 15 4.9 0.0 4.0 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Me-amine-dh_H PF06433.6 ETO29671.1 - 0.015 13.9 0.0 0.042 12.5 0.0 1.6 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) DUF1258 PF06869.7 ETO29671.1 - 0.022 13.8 0.3 0.85 8.6 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1258) Daxx PF03344.10 ETO29672.1 - 0.00051 18.6 16.3 0.00076 18.1 11.3 1.1 1 0 0 1 1 1 1 Daxx Family WD40 PF00400.27 ETO29672.1 - 0.00075 19.2 3.1 0.42 10.5 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat TIMELESS_C PF05029.8 ETO29672.1 - 0.0062 15.5 16.2 0.0096 14.9 11.2 1.2 1 0 0 1 1 1 1 Timeless protein C terminal region Merozoite_SPAM PF07133.6 ETO29672.1 - 0.045 13.6 24.0 0.12 12.2 16.6 1.7 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) MIP-T3 PF10243.4 ETO29672.1 - 0.41 9.0 26.2 0.64 8.4 18.2 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Nucleoplasmin PF03066.10 ETO29672.1 - 2.1 7.8 16.4 4.8 6.6 11.4 1.5 1 0 0 1 1 1 0 Nucleoplasmin DUF2890 PF11081.3 ETO29672.1 - 5.4 7.0 26.1 5.4 7.0 16.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2890) Pkinase PF00069.20 ETO29673.1 - 6.5e-10 38.5 0.0 1.1e-08 34.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Glyco_transf_7N PF13733.1 ETO29674.1 - 0.43 9.9 3.1 0.32 10.3 0.9 1.7 1 1 1 2 2 2 0 N-terminal region of glycosyl transferase group 7 Protamine_P2 PF00841.14 ETO29674.1 - 0.61 10.6 8.6 0.12 12.9 2.3 1.9 2 0 0 2 2 2 0 Sperm histone P2 RIC3 PF15361.1 ETO29674.1 - 2.4 8.3 14.8 0.44 10.7 2.4 2.1 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 G-patch PF01585.18 ETO29676.1 - 2.4e-09 36.8 7.7 3.8e-09 36.1 3.8 2.3 2 1 1 3 3 3 1 G-patch domain G-patch_2 PF12656.2 ETO29676.1 - 0.019 14.7 5.0 0.019 14.7 3.5 2.4 2 1 0 2 2 2 0 DExH-box splicing factor binding site Prp31_C PF09785.4 ETO29676.1 - 0.25 11.7 9.4 1 9.7 6.5 1.9 1 1 0 1 1 1 0 Prp31 C terminal domain DUF1754 PF08555.5 ETO29676.1 - 2 9.0 9.0 0.33 11.5 3.7 1.6 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Pkinase PF00069.20 ETO29677.1 - 5.3e-59 199.4 0.0 6.3e-59 199.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO29677.1 - 2.6e-23 82.4 0.0 2.9e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO29677.1 - 0.00096 18.1 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETO29677.1 - 0.043 12.8 0.0 0.079 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO29677.1 - 0.07 12.8 0.0 0.097 12.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 ETO29677.1 - 0.073 11.8 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 ETO29677.1 - 0.1 11.8 0.0 0.33 10.2 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL GreA_GreB PF01272.14 ETO29678.1 - 0.058 13.1 0.0 0.087 12.5 0.0 1.2 1 0 0 1 1 1 0 Transcription elongation factor, GreA/GreB, C-term Acetyltransf_1 PF00583.19 ETO29679.1 - 1.5e-14 53.7 0.0 3.4e-14 52.6 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETO29679.1 - 3.9e-11 42.9 0.0 6.4e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETO29679.1 - 3.1e-06 27.2 0.0 5.1e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 ETO29679.1 - 9.4e-06 25.8 0.0 1.2e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETO29679.1 - 0.00011 22.0 0.0 0.00018 21.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 ETO29679.1 - 0.00046 20.1 0.6 0.0017 18.3 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Mec-17 PF05301.6 ETO29679.1 - 0.0013 18.6 0.1 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 Touch receptor neuron protein Mec-17 GNAT_acetyltr_2 PF13718.1 ETO29679.1 - 0.012 14.9 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 0 GNAT acetyltransferase 2 DUF2419 PF10343.4 ETO29679.1 - 0.022 14.0 0.1 0.031 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2419) FR47 PF08445.5 ETO29679.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Kelch_1 PF01344.20 ETO29680.1 - 9.2e-12 44.3 0.4 2.1e-07 30.3 0.1 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO29680.1 - 4.8e-09 35.9 3.1 0.048 13.8 0.1 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 ETO29680.1 - 7.9e-08 31.9 4.4 0.0047 16.6 0.1 4.3 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO29680.1 - 1.3e-05 25.1 2.8 0.094 12.9 0.0 4.3 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO29680.1 - 0.00018 21.3 1.4 1 9.3 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 ETO29680.1 - 0.00067 19.3 1.2 0.05 13.3 0.1 3.4 4 0 0 4 4 4 1 Kelch motif AAA_6 PF12774.2 ETO29681.1 - 2.5e-25 89.3 0.1 8.3e-25 87.6 0.0 1.8 2 1 1 3 3 3 1 Hydrolytic ATP binding site of dynein motor region D1 MobB PF03205.9 ETO29681.1 - 0.032 13.9 0.3 0.68 9.6 0.0 2.6 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 ETO29681.1 - 0.038 13.1 0.1 0.074 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 ETO29681.1 - 0.039 13.8 0.1 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 ETO29681.1 - 0.06 13.5 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 ETO29681.1 - 0.062 12.9 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 Archaeal ATPase PduV-EutP PF10662.4 ETO29681.1 - 0.082 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 ETO29681.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.1 ETO29681.1 - 0.13 12.2 0.2 0.59 10.0 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain DHC_N2 PF08393.8 ETO29682.1 - 6.1e-93 311.5 11.2 6.1e-93 311.5 7.8 1.8 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 ETO29682.1 - 1.3e-43 149.1 0.0 2.5e-43 148.2 0.0 1.4 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_16 PF13191.1 ETO29682.1 - 0.017 15.1 0.6 0.12 12.3 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.9 ETO29682.1 - 0.019 14.6 0.1 0.23 11.1 0.0 2.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 ETO29682.1 - 0.042 14.1 0.1 0.37 11.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA PF00004.24 ETO29682.1 - 0.087 13.0 0.0 0.35 11.0 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETO29682.1 - 0.26 11.4 4.3 0.48 10.5 0.0 3.4 4 1 0 4 4 4 0 AAA domain DHC_N1 PF08385.7 ETO29684.1 - 2.5e-16 59.2 5.3 2.7e-16 59.0 3.7 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 CesA PF11439.3 ETO29684.1 - 0.034 14.0 0.7 0.064 13.1 0.1 1.9 2 1 0 2 2 2 0 Type III secretion system filament chaperone CesA YolD PF08863.5 ETO29685.1 - 0.016 15.0 0.3 0.051 13.4 0.2 1.9 1 0 0 1 1 1 0 YolD-like protein Sporozoite_P67 PF05642.6 ETO29686.1 - 0.091 10.6 9.5 0.12 10.1 6.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Daxx PF03344.10 ETO29686.1 - 0.22 9.9 16.5 0.27 9.6 11.5 1.1 1 0 0 1 1 1 0 Daxx Family Zip PF02535.17 ETO29686.1 - 0.33 9.9 6.2 0.52 9.2 4.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2457 PF10446.4 ETO29686.1 - 0.52 8.9 23.3 0.64 8.6 16.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 ETO29686.1 - 0.57 8.0 17.1 0.76 7.6 11.9 1.2 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.7 ETO29686.1 - 1.1 8.3 13.6 1.5 7.9 9.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sigma70_ner PF04546.8 ETO29686.1 - 1.9 8.0 9.9 3.7 7.1 6.9 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.7 ETO29686.1 - 2.1 7.5 14.9 2.9 7.0 10.4 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 ETO29686.1 - 4.2 5.2 13.7 5.4 4.9 9.5 1.1 1 0 0 1 1 1 0 CDC45-like protein PTEN_C2 PF10409.4 ETO29687.1 - 0.061 13.0 0.1 0.08 12.6 0.1 1.3 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein Kelch_6 PF13964.1 ETO29688.1 - 2.2e-09 37.0 3.0 1.9e-06 27.8 0.6 2.4 1 1 1 2 2 2 2 Kelch motif Kelch_4 PF13418.1 ETO29688.1 - 6.2e-07 29.0 0.1 0.0036 17.0 0.0 2.4 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO29688.1 - 9.6e-07 28.2 2.1 5.4e-05 22.6 0.4 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.10 ETO29688.1 - 3.1e-05 23.5 0.3 0.00089 18.9 0.1 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.1 ETO29688.1 - 0.0002 21.1 2.6 0.037 13.9 1.0 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 ETO29688.1 - 0.002 18.2 0.2 0.013 15.6 0.0 2.3 3 0 0 3 3 3 1 Galactose oxidase, central domain NAM PF02365.10 ETO29689.1 - 2 8.6 5.7 2.5 8.3 3.9 1.2 1 0 0 1 1 1 0 No apical meristem (NAM) protein NST1 PF13945.1 ETO29689.1 - 2.2 8.3 10.3 2.6 8.0 7.1 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator MIP-T3 PF10243.4 ETO29690.1 - 9.7e-06 24.3 27.6 9.7e-06 24.3 19.1 3.4 2 1 1 3 3 3 2 Microtubule-binding protein MIP-T3 zf-CCCH_2 PF14608.1 ETO29690.1 - 0.00014 21.6 4.6 0.00014 21.6 3.2 3.2 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type PSD1 PF07587.6 ETO29691.1 - 0.016 14.5 0.4 0.018 14.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1553) SOG2 PF10428.4 ETO29692.1 - 2.3 6.7 26.6 3.1 6.3 18.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.4 ETO29692.1 - 7.5 4.6 22.3 9.4 4.3 15.5 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF3605 PF12239.3 ETO29693.1 - 9.9e-10 38.4 7.3 4.3e-08 33.1 0.6 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3605) NYD-SP28_assoc PF14775.1 ETO29693.1 - 0.064 12.9 1.1 0.064 12.9 0.8 1.9 3 0 0 3 3 3 0 Sperm tail C-terminal domain Endothelin PF00322.12 ETO29693.1 - 0.36 10.0 1.3 1.6 8.0 0.1 2.2 2 0 0 2 2 2 0 Endothelin family Pkinase PF00069.20 ETO29694.1 - 3.1e-42 144.5 3.8 4.1e-36 124.4 1.4 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO29694.1 - 3.2e-19 69.0 3.1 1.8e-18 66.5 0.5 2.1 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO29694.1 - 0.0011 17.9 0.0 0.0018 17.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DHC_N2 PF08393.8 ETO29694.1 - 0.036 12.5 1.8 0.39 9.1 0.3 2.1 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 2 APH PF01636.18 ETO29694.1 - 0.12 12.1 0.1 0.19 11.4 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family SAM_1 PF00536.25 ETO29696.1 - 6.6e-08 32.6 0.1 9.5e-08 32.1 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO29696.1 - 1.2e-07 31.4 0.1 1.9e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ste50p-SAM PF09235.5 ETO29696.1 - 0.00037 20.4 0.1 0.0038 17.2 0.0 2.1 1 1 1 2 2 2 1 Ste50p, sterile alpha motif U79_P34 PF03064.11 ETO29696.1 - 5.5 6.4 8.5 8.3 5.8 5.9 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 zf-TRAF PF02176.13 ETO29699.1 - 1.2e-05 25.5 3.9 1.2e-05 25.5 2.7 2.5 2 1 0 2 2 2 1 TRAF-type zinc finger PTPA PF03095.10 ETO29701.1 - 0.11 11.6 0.1 0.11 11.6 0.1 1.6 2 0 0 2 2 2 0 Phosphotyrosyl phosphate activator (PTPA) protein Ribosomal_L28 PF00830.14 ETO29701.1 - 0.16 11.7 14.2 2.7 7.9 4.8 3.2 2 1 1 3 3 3 0 Ribosomal L28 family zf-C2H2 PF00096.21 ETO29702.1 - 0.00018 21.6 7.5 0.0053 17.0 0.9 5.0 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETO29702.1 - 0.0038 17.4 1.5 0.0038 17.4 1.1 4.8 4 0 0 4 4 4 2 Zinc-finger double domain C1_4 PF07975.7 ETO29702.1 - 0.013 15.4 3.9 0.013 15.4 2.7 3.4 2 1 1 3 3 3 0 TFIIH C1-like domain zf-C2H2_6 PF13912.1 ETO29702.1 - 0.014 15.2 10.7 1 9.3 0.4 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 ETO29702.1 - 0.04 14.2 4.6 0.04 14.2 3.2 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger Lung_7-TM_R PF06814.8 ETO29703.1 - 1.2e-10 40.8 8.7 1.2e-10 40.8 6.0 2.1 3 0 0 3 3 3 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.4 ETO29703.1 - 1.1e-08 34.5 5.2 1.1e-08 34.5 3.6 2.6 4 0 0 4 4 4 1 Rhodopsin-like GPCR transmembrane domain Voltage_CLC PF00654.15 ETO29703.1 - 2.5 7.0 11.0 0.063 12.2 2.1 2.0 2 0 0 2 2 2 0 Voltage gated chloride channel ELFV_dehydrog PF00208.16 ETO29704.1 - 1.7e-51 175.1 0.2 2.4e-51 174.6 0.2 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 ETO29704.1 - 1.7e-35 121.4 0.0 5.3e-35 119.8 0.0 1.8 1 1 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.14 ETO29704.1 - 0.02 14.0 0.0 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 ETO29704.1 - 0.031 14.1 0.1 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.1 ETO29704.1 - 0.053 13.7 0.1 0.21 11.8 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF3523 PF12037.3 ETO29705.1 - 2.6e-33 115.1 19.7 5.7e-28 97.6 11.6 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3523) AAA PF00004.24 ETO29705.1 - 1.9e-21 76.6 0.0 4.1e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 ETO29705.1 - 3.7e-06 26.1 0.0 8.8e-06 24.9 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 ETO29705.1 - 4.7e-06 26.7 0.0 0.0022 18.1 0.0 2.9 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 ETO29705.1 - 1.1e-05 26.2 0.5 5.9e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETO29705.1 - 0.00027 21.0 2.5 0.00051 20.0 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 ETO29705.1 - 0.0015 18.1 0.8 0.0028 17.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 ETO29705.1 - 0.0044 16.7 3.5 0.0086 15.8 0.0 2.9 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 ETO29705.1 - 0.0061 15.9 0.1 0.25 10.7 0.1 2.8 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 ETO29705.1 - 0.0088 16.0 0.0 0.027 14.5 0.0 1.8 1 0 0 1 1 1 1 Sigma-54 interaction domain Zot PF05707.7 ETO29705.1 - 0.011 15.2 3.1 0.09 12.2 0.0 3.2 3 1 1 4 4 4 0 Zonular occludens toxin (Zot) RNA_helicase PF00910.17 ETO29705.1 - 0.024 14.8 0.0 0.062 13.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.1 ETO29705.1 - 0.027 14.8 5.7 0.78 10.0 3.6 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 ETO29705.1 - 0.035 13.9 0.0 0.089 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 ETO29705.1 - 0.071 12.9 2.4 0.09 12.6 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 ETO29705.1 - 0.12 12.6 0.0 0.12 12.6 0.0 2.5 2 1 0 2 2 1 0 AAA domain POX PF07526.6 ETO29706.1 - 0.26 11.5 4.9 0.12 12.5 0.3 2.2 2 0 0 2 2 2 0 Associated with HOX WD40 PF00400.27 ETO29708.1 - 6.1e-70 228.8 19.2 1e-10 41.0 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO29708.1 - 5.4e-14 51.2 4.1 0.0028 15.8 0.0 5.6 2 2 2 5 5 5 5 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO29708.1 - 8.1e-06 25.6 0.2 0.002 18.0 0.0 3.4 3 1 0 3 3 3 1 Domain of unknown function (DUF3601) Nucleoporin_N PF08801.6 ETO29708.1 - 0.00014 20.7 12.2 0.41 9.3 0.1 5.3 2 1 2 5 5 5 4 Nup133 N terminal like PQQ_2 PF13360.1 ETO29708.1 - 0.0097 15.3 1.1 9.1 5.6 0.1 3.5 3 1 0 3 3 3 2 PQQ-like domain WD40 PF00400.27 ETO29709.1 - 2.6e-78 255.3 19.0 2.1e-15 55.9 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO29709.1 - 1.3e-06 26.9 0.4 0.41 8.9 0.0 3.2 1 1 2 3 3 3 3 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO29709.1 - 0.0001 21.2 6.4 1.4 7.6 0.3 4.9 1 1 2 3 3 3 2 Nup133 N terminal like PQQ_2 PF13360.1 ETO29709.1 - 0.0002 20.9 2.6 0.89 8.9 0.0 3.2 2 1 1 3 3 3 2 PQQ-like domain PD40 PF07676.7 ETO29709.1 - 0.00033 20.2 6.1 1.3 8.7 0.0 5.6 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat DUF1652 PF07865.6 ETO29709.1 - 0.0014 18.2 0.0 1.9 8.1 0.0 3.9 3 1 1 4 4 4 1 Protein of unknown function (DUF1652) Resistin PF06954.6 ETO29709.1 - 0.0017 18.5 6.2 1.1 9.6 0.1 5.2 1 1 5 6 6 6 1 Resistin SGL PF08450.7 ETO29709.1 - 0.036 13.4 0.2 0.78 9.0 0.0 2.6 1 1 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region Proteasome_A_N PF10584.4 ETO29709.1 - 8.6 5.7 12.4 4.4 6.7 0.0 4.3 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature F-box-like PF12937.2 ETO29710.1 - 0.00015 21.3 0.1 0.00031 20.3 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETO29710.1 - 0.001 18.6 0.1 0.0025 17.4 0.1 1.6 1 0 0 1 1 1 1 F-box domain PRANC PF09372.5 ETO29710.1 - 0.93 9.4 10.1 0.67 9.9 2.8 3.1 2 1 1 3 3 3 0 PRANC domain SAP PF02037.22 ETO29711.1 - 4.9e-08 32.2 0.4 9.2e-08 31.4 0.3 1.5 1 0 0 1 1 1 1 SAP domain Svf1 PF08622.5 ETO29711.1 - 0.039 12.9 0.0 0.055 12.4 0.0 1.3 1 0 0 1 1 1 0 Svf1-like bZIP_2 PF07716.10 ETO29712.1 - 0.69 9.7 7.2 1.5 8.7 1.6 3.2 2 0 0 2 2 2 0 Basic region leucine zipper Pkinase PF00069.20 ETO29714.1 - 1.2e-50 172.0 0.4 1.8e-49 168.2 0.3 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO29714.1 - 2.6e-16 59.4 0.1 1e-15 57.5 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase 7TM_GPCR_Srab PF10292.4 ETO29714.1 - 0.025 13.2 1.8 0.041 12.5 1.2 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor Kinase-like PF14531.1 ETO29714.1 - 0.089 11.7 0.2 1.9 7.3 0.1 2.2 2 0 0 2 2 2 0 Kinase-like LRR_1 PF00560.28 ETO29715.1 - 0.0061 16.4 16.0 2.4 8.5 0.1 5.9 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_8 PF13855.1 ETO29715.1 - 0.081 12.6 14.1 0.081 12.6 1.5 4.8 5 0 0 5 5 5 0 Leucine rich repeat WBP-1 PF11669.3 ETO29715.1 - 0.21 11.6 7.8 0.67 10.0 4.3 2.5 2 1 0 2 2 2 0 WW domain-binding protein 1 LRR_4 PF12799.2 ETO29715.1 - 0.85 9.3 12.7 0.059 13.0 1.2 3.9 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) DUF4405 PF14358.1 ETO29716.1 - 0.044 13.9 0.7 0.11 12.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) WD40 PF00400.27 ETO29717.1 - 8.1e-36 120.6 14.6 1.5e-07 31.0 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 ETO29717.1 - 1.9e-24 85.3 0.1 4.3e-24 84.2 0.1 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex B56 PF01603.15 ETO29718.1 - 7.2e-48 163.1 19.8 1.1e-41 142.7 4.1 4.1 5 0 0 5 5 5 3 Protein phosphatase 2A regulatory B subunit (B56 family) IncA PF04156.9 ETO29720.1 - 0.38 10.3 26.0 0.15 11.6 5.5 2.1 2 0 0 2 2 2 0 IncA protein FliD_N PF02465.13 ETO29720.1 - 1.4 9.3 19.2 6.8 7.1 6.3 3.1 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DpnII PF04556.7 ETO29721.1 - 0.0055 15.8 0.6 0.0062 15.6 0.4 1.0 1 0 0 1 1 1 1 DpnII restriction endonuclease Borrelia_P83 PF05262.6 ETO29722.1 - 9.8 4.3 21.2 17 3.4 14.7 1.4 1 1 0 1 1 1 0 Borrelia P83/100 protein Tim54 PF11711.3 ETO29723.1 - 0.27 9.7 12.5 0.48 8.9 0.8 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF2457 PF10446.4 ETO29723.1 - 5.1 5.7 42.8 0.018 13.7 16.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) BUD22 PF09073.5 ETO29723.1 - 6.4 5.7 35.5 0.91 8.5 9.0 2.1 2 0 0 2 2 2 0 BUD22 CytochromB561_N PF09786.4 ETO29724.1 - 0.027 12.9 16.4 0.033 12.6 11.4 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Dicty_REP PF05086.7 ETO29724.1 - 0.054 11.2 10.9 0.069 10.9 7.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Macoilin PF09726.4 ETO29724.1 - 0.082 11.1 13.1 0.095 10.9 9.0 1.1 1 0 0 1 1 1 0 Transmembrane protein DNA_pol_viral_N PF00242.12 ETO29724.1 - 0.2 10.6 14.5 0.25 10.3 10.0 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Presenilin PF01080.12 ETO29724.1 - 0.27 10.0 6.7 0.3 9.8 4.6 1.2 1 0 0 1 1 1 0 Presenilin Phyto_Pns9_10 PF05878.6 ETO29724.1 - 0.44 9.5 4.7 3.1 6.7 4.0 1.7 2 0 0 2 2 2 0 Phytoreovirus nonstructural protein Pns9/Pns10 Band_3_cyto PF07565.8 ETO29724.1 - 0.5 9.8 12.7 0.44 10.0 7.4 1.7 1 1 1 2 2 2 0 Band 3 cytoplasmic domain DUF3474 PF11960.3 ETO29724.1 - 0.62 10.0 5.2 1.3 9.0 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) SR-25 PF10500.4 ETO29724.1 - 0.65 9.4 22.6 1 8.7 15.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pex14_N PF04695.8 ETO29724.1 - 0.68 9.9 15.1 0.26 11.3 8.6 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM60A PF15396.1 ETO29724.1 - 1.3 8.7 12.1 2.4 7.8 8.4 1.5 1 0 0 1 1 1 0 Protein Family FAM60A DUF515 PF04415.7 ETO29724.1 - 1.3 7.1 18.6 2 6.5 12.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) MDFI PF15316.1 ETO29724.1 - 1.4 8.9 7.1 2.1 8.2 4.9 1.4 1 0 0 1 1 1 0 MyoD family inhibitor Suf PF05843.9 ETO29724.1 - 3 7.5 10.9 4.5 6.9 7.6 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DHHW PF14286.1 ETO29724.1 - 5.3 6.2 11.4 7.1 5.8 7.9 1.1 1 0 0 1 1 1 0 DHHW protein FLO_LFY PF01698.11 ETO29724.1 - 7 5.3 10.3 9.6 4.9 7.1 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein WD40 PF00400.27 ETO29725.1 - 1.4e-51 170.6 4.8 3.2e-12 45.8 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 ETO29725.1 - 5.1e-08 32.8 0.4 0.00014 21.6 0.0 3.5 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO29725.1 - 1.1e-07 31.4 0.5 0.052 13.2 0.0 4.5 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO29725.1 - 6e-05 21.3 4.9 0.048 11.7 0.0 3.8 1 1 2 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO29725.1 - 0.00099 17.4 0.2 0.1 10.8 0.0 2.8 1 1 1 3 3 3 2 Cytochrome D1 heme domain DUF1258 PF06869.7 ETO29725.1 - 0.0014 17.7 1.2 1.1 8.2 0.0 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF1258) Nucleoporin_N PF08801.6 ETO29725.1 - 0.0014 17.4 4.7 0.16 10.6 0.5 3.4 1 1 1 2 2 2 2 Nup133 N terminal like Hira PF07569.6 ETO29725.1 - 0.0049 16.1 2.2 1 8.5 0.0 4.0 2 2 2 5 5 5 1 TUP1-like enhancer of split Nbas_N PF15492.1 ETO29725.1 - 0.0069 15.5 0.1 0.3 10.1 0.0 3.0 1 1 1 2 2 2 1 Neuroblastoma-amplified sequence, N terminal Tcp10_C PF07202.8 ETO29725.1 - 0.0076 15.8 0.0 2.2 7.7 0.0 2.7 2 1 1 3 3 3 1 T-complex protein 10 C-terminus Gmad1 PF10647.4 ETO29725.1 - 0.014 14.8 0.3 1 8.7 0.1 2.4 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain Proteasome_A_N PF10584.4 ETO29725.1 - 0.048 12.9 2.4 14 5.1 0.0 3.4 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature GATase PF00117.23 ETO29725.1 - 0.08 12.3 0.0 0.76 9.1 0.0 2.3 1 1 1 2 2 2 0 Glutamine amidotransferase class-I Methyltransf_3 PF01596.12 ETO29725.1 - 0.13 11.3 0.0 1.1 8.2 0.0 2.1 1 1 1 2 2 2 0 O-methyltransferase TFIIIC_delta PF12657.2 ETO29725.1 - 0.18 11.4 3.1 0.25 11.0 0.3 2.7 2 2 0 2 2 2 0 Transcription factor IIIC subunit delta N-term WD40 PF00400.27 ETO29726.1 - 6.2e-62 203.4 21.8 2.9e-12 45.9 0.5 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO29726.1 - 1.5e-08 33.3 5.0 0.28 9.2 0.0 4.9 2 2 2 5 5 5 4 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO29726.1 - 0.0035 17.2 0.5 3.9 7.4 0.0 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF3601) Methyltransf_25 PF13649.1 ETO29726.1 - 0.12 12.8 0.0 6.6 7.1 0.0 2.9 3 0 0 3 3 3 0 Methyltransferase domain HAD PF12710.2 ETO29726.1 - 0.25 11.4 4.3 15 5.6 0.0 3.4 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase WD40 PF00400.27 ETO29727.1 - 1.6e-56 186.2 33.8 8.6e-11 41.2 2.8 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO29727.1 - 6.5e-07 27.8 12.3 0.25 9.4 0.2 5.4 1 1 4 6 6 6 5 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO29727.1 - 0.09 12.9 12.4 9 6.6 0.0 5.4 6 1 0 6 6 6 0 Kelch motif Ribosomal_S25 PF03297.10 ETO29729.1 - 0.062 13.3 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 S25 ribosomal protein BRO1 PF03097.13 ETO29730.1 - 4.9e-15 55.1 3.5 6e-15 54.8 2.5 1.0 1 0 0 1 1 1 1 BRO1-like domain APC2 PF08672.6 ETO29731.1 - 0.00061 19.9 0.7 0.02 15.1 0.1 2.8 3 0 0 3 3 3 1 Anaphase promoting complex (APC) subunit 2 CobT PF06213.7 ETO29732.1 - 0.03 13.4 8.9 0.032 13.3 6.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.9 ETO29732.1 - 0.048 11.6 10.1 0.046 11.7 7.0 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 ETO29732.1 - 0.2 10.9 9.3 0.24 10.7 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Gcd10p PF04189.8 ETO29732.1 - 0.44 9.6 3.8 0.49 9.4 2.6 1.1 1 0 0 1 1 1 0 Gcd10p family POX PF07526.6 ETO29732.1 - 1.3 9.2 4.3 1.8 8.7 3.0 1.2 1 0 0 1 1 1 0 Associated with HOX NOA36 PF06524.7 ETO29732.1 - 2.3 7.3 15.9 2.8 7.1 11.0 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2076 PF09849.4 ETO29732.1 - 6.4 6.7 15.3 7.1 6.6 10.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) FtsJ PF01728.14 ETO29733.1 - 2.4e-09 37.4 0.0 6.3e-09 36.0 0.0 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 ETO29733.1 - 0.041 13.4 0.2 0.13 11.8 0.0 1.9 3 0 0 3 3 3 0 Methyltransferase domain DUF3994 PF13159.1 ETO29734.1 - 1.3 9.2 9.3 0.21 11.8 2.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3994) Cnd1_N PF12922.2 ETO29735.1 - 0.00083 19.0 0.6 0.42 10.2 0.1 2.2 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1, N-term NAM-associated PF14303.1 ETO29735.1 - 0.23 11.7 9.4 3.2 8.0 2.0 2.2 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain DUF3915 PF13054.1 ETO29735.1 - 0.49 10.3 14.4 1.9 8.4 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) NST1 PF13945.1 ETO29735.1 - 3 7.8 15.3 1 9.4 4.0 2.2 2 0 0 2 2 2 0 Salt tolerance down-regulator DUF2407_C PF13373.1 ETO29735.1 - 8.9 6.2 6.9 0.55 10.1 0.6 2.1 2 0 0 2 2 2 0 DUF2407 C-terminal domain DUF1510 PF07423.6 ETO29736.1 - 8e-05 22.1 4.8 0.00012 21.5 3.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) IncA PF04156.9 ETO29736.1 - 0.35 10.4 2.3 0.5 9.9 1.6 1.2 1 0 0 1 1 1 0 IncA protein ABC2_membrane_3 PF12698.2 ETO29736.1 - 4 6.3 10.6 5 6.0 7.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF334 PF03904.8 ETO29737.1 - 0.0036 16.6 8.5 0.0038 16.5 5.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF334) Birna_RdRp PF04197.7 ETO29737.1 - 0.039 11.9 3.2 0.043 11.8 2.2 1.0 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) Fib_alpha PF08702.5 ETO29737.1 - 0.084 13.0 4.0 0.089 12.9 2.5 1.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family ETRAMP PF09716.5 ETO29737.1 - 0.81 9.6 6.0 1.8 8.5 4.2 1.5 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Ribosomal_L21p PF00829.16 ETO29738.1 - 1.5e-09 37.8 0.2 2.4e-09 37.2 0.1 1.3 1 1 0 1 1 1 1 Ribosomal prokaryotic L21 protein OST-HTH PF12872.2 ETO29739.1 - 0.0064 16.3 0.1 0.016 15.0 0.1 1.6 1 0 0 1 1 1 1 OST-HTH/LOTUS domain SRP-alpha_N PF04086.8 ETO29739.1 - 0.055 12.8 27.4 0.11 11.8 6.9 2.7 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal GAGA_bind PF06217.7 ETO29739.1 - 3 7.7 26.4 0.76 9.6 5.6 2.3 2 0 0 2 2 2 0 GAGA binding protein-like family ShK PF01549.19 ETO29739.1 - 3.3 8.1 6.6 17 5.8 1.0 2.5 1 1 1 2 2 2 0 ShK domain-like SNARE PF05739.14 ETO29740.1 - 7.5e-10 38.3 3.8 7.5e-10 38.3 2.6 1.8 2 0 0 2 2 2 1 SNARE domain PMC2NT PF08066.7 ETO29740.1 - 0.011 16.0 0.5 0.023 15.0 0.3 1.5 1 0 0 1 1 1 0 PMC2NT (NUC016) domain G-alpha PF00503.15 ETO29741.1 - 9.3e-58 195.7 9.3 3.1e-49 167.6 4.9 2.1 2 0 0 2 2 2 2 G-protein alpha subunit Arf PF00025.16 ETO29741.1 - 2.4e-05 23.6 0.8 0.0043 16.3 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETO29741.1 - 0.0074 16.2 0.2 0.1 12.5 0.1 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase MRP-S32 PF10210.4 ETO29741.1 - 0.0084 16.4 3.2 0.54 10.6 0.0 3.0 3 0 0 3 3 3 1 Mitochondrial 28S ribosomal protein S32 AAA_29 PF13555.1 ETO29741.1 - 0.027 13.9 0.0 0.066 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.7 ETO29741.1 - 0.24 10.5 5.9 1.4 7.9 0.3 2.8 1 1 1 2 2 2 0 Gtr1/RagA G protein conserved region FOP_dimer PF09398.5 ETO29742.1 - 0.007 16.3 0.0 0.032 14.2 0.0 2.2 1 0 0 1 1 1 1 FOP N terminal dimerisation domain APG6 PF04111.7 ETO29742.1 - 0.62 9.0 25.1 0.056 12.4 11.1 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 Hemerythrin PF01814.18 ETO29742.1 - 1.1 9.4 5.3 13 5.9 0.2 3.2 3 0 0 3 3 3 0 Hemerythrin HHE cation binding domain Cauli_AT PF03233.8 ETO29742.1 - 1.9 8.1 17.0 0.57 9.8 3.5 2.9 3 0 0 3 3 3 0 Aphid transmission protein ERM PF00769.14 ETO29742.1 - 2.6 7.4 24.4 6.2 6.2 16.9 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF4404 PF14357.1 ETO29742.1 - 3 8.3 15.1 2.8 8.4 2.8 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) DUF1664 PF07889.7 ETO29742.1 - 6.2 6.6 12.6 0.48 10.2 0.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2968 PF11180.3 ETO29742.1 - 6.7 6.0 19.2 0.47 9.7 6.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Spectrin PF00435.16 ETO29742.1 - 6.7 7.0 18.6 1.3 9.3 6.6 2.9 2 1 1 3 3 3 0 Spectrin repeat TMF_DNA_bd PF12329.3 ETO29742.1 - 8 6.3 22.5 0.12 12.2 3.3 3.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Sulfotransfer_3 PF13469.1 ETO29743.1 - 0.0001 23.2 4.4 0.00032 21.6 3.1 1.7 1 1 0 1 1 1 1 Sulfotransferase family DDHD PF02862.12 ETO29745.1 - 8.4 6.1 11.0 21 4.7 7.7 1.7 1 1 0 1 1 1 0 DDHD domain DUF2552 PF10827.3 ETO29746.1 - 0.049 13.5 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2552) Caudo_TAP PF02413.12 ETO29748.1 - 0.09 12.9 0.3 0.14 12.3 0.2 1.4 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein DUF3328 PF11807.3 ETO29749.1 - 0.05 13.2 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) TPR_12 PF13424.1 ETO29751.1 - 6.9e-113 368.7 46.5 2.3e-22 78.7 0.7 6.4 2 1 5 8 8 8 8 Tetratricopeptide repeat TPR_1 PF00515.23 ETO29751.1 - 6.4e-63 205.9 52.1 5.4e-08 32.1 0.5 9.9 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 ETO29751.1 - 6.4e-55 182.7 34.8 7.9e-12 44.6 4.2 6.4 3 2 2 6 6 6 6 TPR repeat TPR_7 PF13176.1 ETO29751.1 - 5.6e-54 175.7 21.9 9.4e-06 25.0 0.1 9.9 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.12 ETO29751.1 - 4.1e-53 173.0 37.6 2.8e-06 26.8 0.1 10.3 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_10 PF13374.1 ETO29751.1 - 2.9e-52 173.1 0.0 2e-05 24.3 0.0 9.3 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_8 PF13181.1 ETO29751.1 - 8.7e-42 137.7 52.1 3.1e-05 23.4 0.3 10.5 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_17 PF13431.1 ETO29751.1 - 4.5e-25 85.7 20.9 0.051 13.7 0.1 10.3 9 1 0 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.1 ETO29751.1 - 2e-22 79.3 1.3 0.0059 17.2 0.2 6.7 5 2 1 6 6 6 6 Tetratricopeptide repeat TPR_14 PF13428.1 ETO29751.1 - 1.1e-20 72.2 0.1 0.47 11.2 0.0 9.4 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_6 PF13174.1 ETO29751.1 - 4.6e-17 61.2 18.6 0.19 12.2 0.0 10.1 10 0 0 10 10 10 4 Tetratricopeptide repeat Apc3 PF12895.2 ETO29751.1 - 2.7e-15 56.2 32.1 2.1e-05 24.5 2.0 6.4 2 1 5 7 7 7 7 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 ETO29751.1 - 2.7e-12 46.3 28.5 0.68 9.8 0.0 10.0 9 1 1 10 10 10 3 MIT (microtubule interacting and transport) domain TPR_19 PF14559.1 ETO29751.1 - 2.7e-08 34.0 8.2 0.37 11.1 0.2 6.4 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_3 PF07720.7 ETO29751.1 - 1.5e-06 27.8 39.0 0.1 12.4 2.4 8.0 9 0 0 9 9 8 4 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO29751.1 - 1.4e-05 24.2 9.0 1.3 8.3 0.1 6.5 7 0 0 7 7 6 2 SHNi-TPR TPR_5 PF12688.2 ETO29751.1 - 0.00067 19.6 1.9 3.3 7.7 0.0 5.0 3 1 3 6 6 6 1 Tetratrico peptide repeat Sel1 PF08238.7 ETO29751.1 - 0.026 15.1 24.5 0.3 11.7 0.5 6.9 8 0 0 8 8 6 0 Sel1 repeat DUF627 PF04781.7 ETO29751.1 - 0.033 13.8 14.4 1.6 8.3 0.0 6.5 3 1 4 7 7 7 0 Protein of unknown function (DUF627) Glyoxalase PF00903.20 ETO29751.1 - 0.054 13.4 3.7 1.6 8.7 0.4 3.6 3 1 0 3 3 3 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Tropomyosin_1 PF12718.2 ETO29751.1 - 0.091 12.6 0.5 0.51 10.1 0.0 2.5 3 0 0 3 3 2 0 Tropomyosin like PPR PF01535.15 ETO29751.1 - 0.13 12.3 13.8 22 5.3 0.0 7.9 9 1 1 10 10 9 0 PPR repeat Prefoldin PF02996.12 ETO29751.1 - 0.27 10.9 5.8 10 5.8 0.1 3.9 2 2 1 3 3 3 0 Prefoldin subunit CD34_antigen PF06365.7 ETO29752.1 - 0.041 13.5 0.1 0.15 11.7 0.0 1.7 1 1 1 2 2 2 0 CD34/Podocalyxin family DUF912 PF06024.7 ETO29752.1 - 0.058 13.4 1.4 18 5.4 0.0 3.3 1 1 2 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4293 PF14126.1 ETO29752.1 - 0.84 9.5 8.4 0.12 12.2 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Kinesin PF00225.18 ETO29753.1 - 5.6e-17 61.4 0.0 7.7e-17 60.9 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain AAA_23 PF13476.1 ETO29753.1 - 0.63 10.3 5.0 0.42 10.9 0.3 2.0 2 0 0 2 2 2 0 AAA domain Guanylate_cyc PF00211.15 ETO29754.1 - 3.8e-40 137.1 0.0 6.3e-40 136.5 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Jiraiya PF15038.1 ETO29754.1 - 0.065 12.6 0.3 0.065 12.6 0.2 2.5 2 1 0 2 2 2 0 Jiraiya IFNGR1 PF07140.6 ETO29755.1 - 0.0032 17.1 1.8 0.012 15.3 1.3 2.1 1 0 0 1 1 1 1 Interferon gamma receptor (IFNGR1) Metallophos PF00149.23 ETO29756.1 - 3e-21 75.7 3.9 5.4e-21 74.9 2.7 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Mre11_DNA_bind PF04152.9 ETO29756.1 - 2.6e-18 66.5 5.9 2.7e-18 66.4 0.0 3.1 2 1 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos_2 PF12850.2 ETO29756.1 - 6.1e-08 32.6 0.1 6.8e-07 29.2 0.1 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TFIIF_alpha PF05793.7 ETO29757.1 - 0.026 12.8 51.9 0.037 12.4 36.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MIP-T3 PF10243.4 ETO29757.1 - 4.3 5.7 55.5 5.3 5.3 38.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2542 PF10808.3 ETO29760.1 - 0.024 14.9 0.6 0.024 14.9 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2542) Pantoate_ligase PF02569.10 ETO29761.1 - 2.3e-65 220.1 0.1 3.1e-65 219.7 0.0 1.2 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Pantoate_transf PF02548.10 ETO29761.1 - 1e-42 146.0 0.0 1.7e-42 145.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase FAD_syn PF06574.7 ETO29761.1 - 0.0055 16.3 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 FAD synthetase Ldl_recept_a PF00057.13 ETO29762.1 - 5.1e-31 106.2 63.4 1.7e-10 40.6 5.9 4.6 4 0 0 4 4 4 4 Low-density lipoprotein receptor domain class A HYR PF02494.11 ETO29762.1 - 7.2e-06 25.9 0.4 2.2e-05 24.3 0.3 1.8 1 0 0 1 1 1 1 HYR domain Peptidase_M20 PF01546.23 ETO29763.1 - 1.1e-05 25.0 0.0 1.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF3684 PF12449.3 ETO29763.1 - 0.038 11.5 1.5 0.048 11.2 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3684) G-alpha PF00503.15 ETO29764.1 - 4.6e-52 177.0 0.3 5.4e-52 176.7 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO29764.1 - 8.2e-05 21.9 0.0 0.00018 20.7 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family Peptidase_M20 PF01546.23 ETO29765.1 - 1.3e-19 70.4 0.0 1.9e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 ETO29765.1 - 3.1e-11 42.9 0.0 1.5e-10 40.7 0.0 2.1 2 0 0 2 2 2 1 Peptidase dimerisation domain TPR_12 PF13424.1 ETO29766.1 - 6.5e-34 115.7 9.3 1.8e-16 59.8 0.5 3.5 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO29766.1 - 1.6e-29 100.2 26.4 6.4e-07 28.7 3.1 5.3 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETO29766.1 - 1e-28 98.7 25.4 8.3e-09 34.9 2.5 3.3 1 1 3 4 4 4 4 TPR repeat TPR_2 PF07719.12 ETO29766.1 - 1.9e-27 92.9 19.0 5.7e-06 25.8 2.0 5.2 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.1 ETO29766.1 - 2.2e-21 73.9 23.9 0.00037 20.0 2.4 5.3 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.1 ETO29766.1 - 1.9e-20 70.9 7.5 0.00074 19.1 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO29766.1 - 5.9e-15 54.6 0.0 0.0019 18.0 0.1 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO29766.1 - 1.8e-10 40.5 0.0 0.74 10.6 0.0 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO29766.1 - 3.7e-10 39.5 9.6 0.0076 16.6 0.8 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO29766.1 - 1.4e-08 35.1 0.0 0.0073 16.9 0.0 4.3 3 2 1 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO29766.1 - 3e-07 30.4 11.6 2.5e-05 24.3 3.7 3.7 1 1 4 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 ETO29766.1 - 5.5e-06 26.1 10.8 0.13 12.1 1.2 4.7 4 1 1 5 5 5 2 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.1 ETO29766.1 - 5.7e-05 22.9 23.2 0.0017 18.1 1.3 4.2 5 0 0 5 5 5 3 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.1 ETO29766.1 - 9e-05 22.7 1.0 0.59 10.5 0.0 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO29766.1 - 0.00011 22.1 9.0 8.9 6.7 0.0 6.2 5 2 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 ETO29766.1 - 0.021 14.7 0.1 25 4.7 0.1 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat SPO22 PF08631.5 ETO29766.1 - 0.058 12.4 5.4 7.3 5.5 0.1 3.2 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like SHNi-TPR PF10516.4 ETO29766.1 - 0.16 11.2 3.9 5.2 6.4 0.1 3.7 4 0 0 4 4 4 0 SHNi-TPR DUF2225 PF09986.4 ETO29766.1 - 0.23 10.9 13.2 0.69 9.3 0.7 3.4 2 2 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_3 PF07720.7 ETO29766.1 - 1.1 9.1 11.8 0.15 11.9 3.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.4 ETO29766.1 - 2.4 7.5 7.9 12 5.2 0.1 3.3 1 1 1 4 4 4 0 26S proteasome subunit RPN7 Sel1 PF08238.7 ETO29766.1 - 8.3 7.1 8.8 1.9 9.2 0.6 3.5 4 0 0 4 4 4 0 Sel1 repeat CmcH_NodU PF02543.10 ETO29767.1 - 0.48 9.4 7.4 0.61 9.1 5.2 1.2 1 0 0 1 1 1 0 Carbamoyltransferase Pfg27 PF09216.5 ETO29768.1 - 0.097 12.2 0.2 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Pfg27 PSP PF04046.11 ETO29769.1 - 2.2e-14 52.5 2.8 4.7e-14 51.5 1.9 1.6 1 0 0 1 1 1 1 PSP Tim44 PF04280.10 ETO29769.1 - 0.13 12.2 1.6 0.2 11.6 1.1 1.2 1 0 0 1 1 1 0 Tim44-like domain Myc_N PF01056.13 ETO29769.1 - 0.26 10.3 2.2 0.43 9.7 1.6 1.2 1 0 0 1 1 1 0 Myc amino-terminal region EAP30 PF04157.11 ETO29770.1 - 5.6e-61 205.5 0.1 6.7e-61 205.2 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family TrmB PF01978.14 ETO29770.1 - 0.011 15.3 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB RPA_C PF08784.6 ETO29770.1 - 0.05 14.0 0.1 0.45 10.9 0.0 2.4 3 0 0 3 3 3 0 Replication protein A C terminal Mnd1 PF03962.10 ETO29770.1 - 0.06 13.0 3.4 3.6 7.2 0.1 2.8 3 0 0 3 3 3 0 Mnd1 family AKNA PF12443.3 ETO29770.1 - 0.085 12.8 1.0 13 5.9 0.0 2.3 2 0 0 2 2 2 0 AT-hook-containing transcription factor TBPIP PF07106.8 ETO29770.1 - 0.16 11.5 3.0 0.17 11.4 0.6 1.9 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Colicin-DNase PF12639.2 ETO29770.1 - 0.16 12.2 1.7 0.21 11.8 0.5 1.6 2 0 0 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin Pkinase PF00069.20 ETO29772.1 - 1.3e-14 54.0 0.0 7.2e-14 51.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO29772.1 - 0.013 14.5 0.0 0.026 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase TcpE PF12648.2 ETO29772.1 - 0.024 14.7 0.2 3.4 7.8 0.0 2.2 2 0 0 2 2 2 0 TcpE family DUF3947 PF13135.1 ETO29772.1 - 2.4 8.3 4.7 0.36 11.0 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3947) Peroxin-3 PF04882.7 ETO29773.1 - 0.029 13.0 0.2 0.04 12.6 0.1 1.5 2 0 0 2 2 2 0 Peroxin-3 His_Phos_1 PF00300.17 ETO29774.1 - 2.8e-11 43.7 0.0 4.4e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Elongin_A PF06881.6 ETO29774.1 - 0.28 11.5 2.9 0.54 10.6 1.9 1.5 1 1 1 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Zip PF02535.17 ETO29777.1 - 8.5e-11 41.4 0.5 1.7e-10 40.4 0.3 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter Photo_RC PF00124.14 ETO29777.1 - 0.064 12.2 0.9 0.14 11.1 0.2 1.7 1 1 1 2 2 2 0 Photosynthetic reaction centre protein Myc_target_1 PF15179.1 ETO29777.1 - 0.31 10.6 2.5 2.3 7.7 0.0 2.3 2 1 0 2 2 2 0 Myc target protein 1 DUF2201_N PF13203.1 ETO29778.1 - 0.18 10.9 3.7 0.04 13.0 0.4 1.4 2 0 0 2 2 2 0 Putative metallopeptidase domain Zip PF02535.17 ETO29778.1 - 0.2 10.6 0.3 0.28 10.1 0.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Peroxin-13_N PF04088.8 ETO29778.1 - 0.45 10.4 1.8 2 8.3 0.3 2.3 1 1 1 2 2 2 0 Peroxin 13, N-terminal region DUF1215 PF06744.7 ETO29779.1 - 0.072 12.7 0.0 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1215) Strumpellin PF10266.4 ETO29780.1 - 7.8e-56 189.1 6.5 9e-56 188.9 4.5 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin Strumpellin PF10266.4 ETO29781.1 - 8e-69 232.1 2.1 9.6e-69 231.9 1.4 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin DUF310 PF03750.8 ETO29781.1 - 0.023 14.9 0.1 0.042 14.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF310) Ribosomal_L1 PF00687.16 ETO29782.1 - 3.4e-36 124.6 1.8 4.6e-36 124.2 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family TMEM220 PF15071.1 ETO29783.1 - 0.1 13.0 0.1 0.23 11.9 0.1 1.6 1 0 0 1 1 1 0 Transmembrane family 220, helix WD40 PF00400.27 ETO29784.1 - 1.1e-80 262.8 17.6 8.4e-12 44.4 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO29784.1 - 2.1e-06 26.2 1.3 0.073 11.3 0.0 3.4 2 1 1 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.3 ETO29784.1 - 7.7e-06 24.3 3.4 0.54 8.3 0.1 4.4 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Resistin PF06954.6 ETO29784.1 - 0.0001 22.4 0.2 3.5 7.9 0.0 4.5 3 1 1 4 4 4 1 Resistin PQQ_2 PF13360.1 ETO29784.1 - 0.00029 20.3 0.8 0.13 11.7 0.4 3.2 1 1 2 3 3 3 2 PQQ-like domain Kelch_1 PF01344.20 ETO29784.1 - 0.0016 17.9 3.8 0.012 15.1 0.4 3.8 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 ETO29784.1 - 0.0019 18.1 4.2 0.091 12.7 0.0 4.3 5 0 0 5 5 4 1 Kelch motif Kelch_6 PF13964.1 ETO29784.1 - 0.015 15.4 5.0 0.57 10.4 0.2 4.7 4 1 1 5 5 5 0 Kelch motif Kelch_4 PF13418.1 ETO29784.1 - 0.018 14.7 4.0 0.92 9.3 0.1 4.7 5 1 1 6 6 6 0 Galactose oxidase, central domain MRJP PF03022.11 ETO29784.1 - 0.022 14.0 1.4 0.04 13.1 0.0 2.1 3 0 0 3 3 3 0 Major royal jelly protein Kelch_3 PF13415.1 ETO29784.1 - 0.038 14.1 0.0 1.6 8.9 0.0 3.1 2 0 0 2 2 2 0 Galactose oxidase, central domain PD40 PF07676.7 ETO29784.1 - 0.099 12.3 5.7 18 5.1 0.0 5.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat HATPase_c_3 PF13589.1 ETO29784.1 - 0.83 9.3 4.1 0.41 10.2 0.0 2.2 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Proteasome_A_N PF10584.4 ETO29784.1 - 0.91 8.9 6.5 12 5.3 0.0 4.3 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature DUF427 PF04248.7 ETO29787.1 - 0.11 12.1 0.1 6.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF427) Peptidase_C97 PF05903.9 ETO29788.1 - 0.0095 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain Phage_RpbA PF10789.4 ETO29788.1 - 0.069 13.0 0.4 0.99 9.2 0.0 2.2 2 0 0 2 2 2 0 Phage RNA polymerase binding, RpbA PHO4 PF01384.15 ETO29789.1 - 1.7e-35 122.2 14.1 2.5e-35 121.6 9.8 1.3 1 0 0 1 1 1 1 Phosphate transporter family DUF2108 PF09881.4 ETO29789.1 - 1.8 8.4 8.7 0.99 9.2 2.5 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2108) PHO4 PF01384.15 ETO29790.1 - 1.7e-45 155.0 0.3 2.1e-45 154.8 0.2 1.0 1 0 0 1 1 1 1 Phosphate transporter family NAPRTase PF04095.11 ETO29791.1 - 6.2e-28 97.7 0.0 2.7e-25 89.0 0.0 2.4 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family DUF2183 PF09949.4 ETO29792.1 - 0.038 13.9 0.1 0.12 12.3 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) MIP-T3 PF10243.4 ETO29794.1 - 0.018 13.5 44.6 0.026 13.0 30.9 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 FH2 PF02181.18 ETO29795.1 - 1.9e-29 102.7 8.3 5.1e-23 81.5 0.9 2.1 2 0 0 2 2 2 2 Formin Homology 2 Domain Matrilin_ccoil PF10393.4 ETO29795.1 - 0.029 13.7 0.6 0.16 11.3 0.3 2.2 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin zf-DHHC PF01529.15 ETO29795.1 - 0.43 9.9 5.3 0.81 9.0 3.7 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase Trypan_PARP PF05887.6 ETO29796.1 - 1.2 8.9 17.9 3 7.6 12.4 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Mucin PF01456.12 ETO29797.1 - 0.3 10.8 1.5 0.6 9.8 0.0 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein Papilloma_E5 PF03025.9 ETO29797.1 - 1 9.3 9.7 1.5 8.8 6.7 1.1 1 0 0 1 1 1 0 Papillomavirus E5 Daxx PF03344.10 ETO29797.1 - 3.6 5.9 58.2 0.055 11.9 34.6 1.8 1 1 0 1 1 1 0 Daxx Family SAM_2 PF07647.12 ETO29798.1 - 1.5e-05 24.7 0.0 3.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO29798.1 - 0.00025 21.1 0.0 0.00046 20.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DNA_pol3_a_NII PF11490.3 ETO29798.1 - 0.17 11.4 12.3 0.39 10.3 8.5 1.6 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II DUF808 PF05661.7 ETO29798.1 - 0.86 8.3 3.2 1.2 7.8 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF808) Cytadhesin_P30 PF07271.6 ETO29798.1 - 7 5.8 10.4 9.9 5.3 7.2 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 RIG-I_C-RD PF11648.3 ETO29799.1 - 0.1 12.4 3.6 0.21 11.4 2.3 1.7 1 1 1 2 2 2 0 C-terminal domain of RIG-I Cytochrom_c3_2 PF14537.1 ETO29799.1 - 2.7 8.4 7.5 3.5 8.0 1.4 2.3 1 1 1 2 2 2 0 Cytochrome c3 Pkinase PF00069.20 ETO29800.1 - 8e-20 71.0 0.1 1.5e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO29800.1 - 2.7e-06 26.6 0.1 2.7e-05 23.3 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase DUF2784 PF10861.3 ETO29800.1 - 0.046 13.5 0.6 0.17 11.6 0.4 2.0 1 0 0 1 1 1 0 Protein of Unknown function (DUF2784) Pkinase PF00069.20 ETO29801.1 - 1.6e-15 56.9 0.0 2.2e-15 56.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO29801.1 - 3.6e-05 22.9 0.1 7.9e-05 21.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase LETM1 PF07766.8 ETO29801.1 - 0.09 11.7 0.2 0.12 11.3 0.2 1.1 1 0 0 1 1 1 0 LETM1-like protein DUF4612 PF15389.1 ETO29802.1 - 0.12 13.0 5.4 0.17 12.5 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4612) Ta0938 PF11494.3 ETO29803.1 - 0.064 13.3 0.4 0.2 11.7 0.0 1.9 2 1 0 2 2 2 0 Ta0938 Gln-synt_C PF00120.19 ETO29804.1 - 1.3e-15 57.2 0.0 2.1e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 ETO29804.1 - 1.4e-13 50.2 0.0 2.4e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Daxx PF03344.10 ETO29806.1 - 1.6 7.1 36.4 2.2 6.6 25.2 1.1 1 0 0 1 1 1 0 Daxx Family Ycf1 PF05758.7 ETO29806.1 - 9 3.8 17.9 12 3.4 12.4 1.2 1 0 0 1 1 1 0 Ycf1 FdhE PF04216.7 ETO29807.1 - 0.18 11.5 1.3 0.18 11.4 0.9 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Pox_Ag35 PF03286.9 ETO29807.1 - 0.29 10.6 6.1 0.35 10.3 4.2 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Astro_capsid PF03115.9 ETO29807.1 - 0.32 9.2 5.2 0.36 9.0 3.6 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Drc1-Sld2 PF11719.3 ETO29807.1 - 0.32 10.0 6.4 0.35 9.8 4.4 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein DUF2457 PF10446.4 ETO29807.1 - 2 7.0 11.5 2.8 6.5 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF2718 PF10918.3 ETO29807.1 - 2.6 8.0 4.7 5.1 7.1 3.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2718) DUF3584 PF12128.3 ETO29809.1 - 1.6e-05 22.5 41.6 1.9e-05 22.2 28.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Spc7 PF08317.6 ETO29809.1 - 1 7.9 51.9 0.43 9.1 7.2 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein Reo_sigmaC PF04582.7 ETO29809.1 - 2.2 7.3 7.4 4.2 6.4 0.3 2.5 1 1 1 3 3 3 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 ETO29809.1 - 2.8 7.7 10.6 1.6 8.5 1.2 2.8 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus HisKA_3 PF07730.8 ETO29809.1 - 4.2 7.7 6.6 6.9 7.0 0.0 3.5 4 0 0 4 4 4 0 Histidine kinase DUF285 PF03382.9 ETO29810.1 - 0.017 14.6 0.4 0.024 14.2 0.3 1.3 1 0 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 FRG1 PF06229.7 ETO29810.1 - 0.61 9.5 5.7 0.045 13.2 0.9 1.4 2 0 0 2 2 2 0 FRG1-like family Aldedh PF00171.17 ETO29811.1 - 2.2e-26 92.2 0.3 2.4e-26 92.0 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3047 PF11249.3 ETO29811.1 - 0.0068 15.8 0.1 0.0086 15.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3047) Biotin_carb_C PF02785.14 ETO29811.1 - 0.031 14.2 0.1 0.045 13.7 0.0 1.2 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain LUC7 PF03194.10 ETO29811.1 - 0.075 12.5 1.2 0.094 12.2 0.8 1.2 1 1 0 1 1 1 0 LUC7 N_terminus FleQ PF06490.6 ETO29811.1 - 0.11 12.6 0.0 1.2 9.3 0.0 1.9 1 1 1 2 2 2 0 Flagellar regulatory protein FleQ N2227 PF07942.7 ETO29811.1 - 0.13 11.1 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 N2227-like protein TPK_B1_binding PF04265.9 ETO29812.1 - 0.051 13.2 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, vitamin B1 binding domain Sds3 PF08598.6 ETO29812.1 - 0.057 12.9 0.5 0.077 12.5 0.3 1.3 1 0 0 1 1 1 0 Sds3-like 7tm_1 PF00001.16 ETO29814.1 - 0.048 12.7 0.1 0.055 12.6 0.1 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) B56 PF01603.15 ETO29815.1 - 1.2e-62 211.8 0.3 1.5e-62 211.5 0.2 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) B56 PF01603.15 ETO29816.1 - 1.9e-24 86.0 0.6 2.3e-24 85.8 0.4 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) RNA_pol_Rpb1_R PF05001.8 ETO29816.1 - 2.2 8.6 7.9 8.2 6.8 0.5 2.6 2 0 0 2 2 2 0 RNA polymerase Rpb1 C-terminal repeat DUF2654 PF10849.3 ETO29817.1 - 0.013 15.2 0.1 0.021 14.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2654) HEAT_2 PF13646.1 ETO29818.1 - 4.8e-34 116.5 16.5 1e-09 38.5 0.5 5.6 2 1 6 8 8 8 7 HEAT repeats Ank_2 PF12796.2 ETO29818.1 - 7.1e-21 74.3 0.4 2e-11 44.0 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO29818.1 - 2.6e-16 59.6 0.4 4.4e-09 36.6 0.0 3.5 2 1 2 4 4 4 2 Ankyrin repeats (many copies) HEAT PF02985.17 ETO29818.1 - 8.5e-14 50.3 8.8 0.0038 17.1 0.1 10.3 10 0 0 10 10 10 1 HEAT repeat DUF294 PF03445.8 ETO29818.1 - 1.6e-11 43.9 0.1 6.6e-09 35.4 0.0 3.5 3 0 0 3 3 3 1 Putative nucleotidyltransferase DUF294 Ank_5 PF13857.1 ETO29818.1 - 2.2e-10 40.3 1.2 5.4e-09 36.0 0.0 3.3 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO29818.1 - 5.2e-09 35.4 0.3 3.8e-06 26.6 0.0 4.7 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.25 ETO29818.1 - 1.3e-06 27.8 0.9 1.7e-05 24.3 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat HEAT_EZ PF13513.1 ETO29818.1 - 1.4e-06 28.5 21.0 0.051 14.0 0.1 8.8 6 3 5 11 11 11 4 HEAT-like repeat HEAT_PBS PF03130.11 ETO29818.1 - 0.00092 19.4 12.2 4.5 8.0 0.0 6.3 6 1 0 6 6 6 2 PBS lyase HEAT-like repeat NTP_transf_2 PF01909.18 ETO29818.1 - 0.0028 17.9 0.3 0.018 15.3 0.0 2.6 3 0 0 3 3 1 1 Nucleotidyltransferase domain LRR_6 PF13516.1 ETO29818.1 - 0.029 14.3 4.8 3.8 7.8 0.2 4.3 3 0 0 3 3 3 0 Leucine Rich repeat UBX PF00789.15 ETO29820.1 - 3.9e-09 36.4 0.3 1.8e-08 34.3 0.0 2.1 1 1 1 2 2 2 1 UBX domain DUF4163 PF13739.1 ETO29820.1 - 0.0073 17.0 3.8 0.013 16.2 2.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4163) HicB PF05534.7 ETO29820.1 - 0.053 13.1 0.1 0.16 11.5 0.0 1.8 1 0 0 1 1 1 0 HicB family DUF918 PF06033.6 ETO29820.1 - 0.055 12.9 0.2 0.096 12.2 0.1 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF918) Maf1 PF09174.5 ETO29820.1 - 0.08 12.7 4.1 2.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Maf1 regulator DDHD PF02862.12 ETO29820.1 - 0.15 11.8 5.2 0.15 11.7 3.6 1.1 1 0 0 1 1 1 0 DDHD domain Pex16 PF08610.5 ETO29820.1 - 0.31 9.9 5.4 0.41 9.5 3.7 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Mlo PF03094.10 ETO29820.1 - 0.39 8.7 2.3 0.45 8.5 1.6 1.1 1 0 0 1 1 1 0 Mlo family Peptidase_S49_N PF08496.5 ETO29820.1 - 1.4 8.6 7.8 1.9 8.2 5.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2457 PF10446.4 ETO29822.1 - 0.0043 15.8 27.1 0.0043 15.8 18.8 3.5 2 1 1 3 3 3 1 Protein of unknown function (DUF2457) PepSY_TM_1 PF13172.1 ETO29822.1 - 0.25 11.1 2.1 0.49 10.2 1.4 1.5 1 0 0 1 1 1 0 PepSY-associated TM helix WD40 PF00400.27 ETO29823.1 - 4.9e-63 206.9 25.9 1e-10 41.0 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO29823.1 - 4.8e-18 64.6 5.0 9.6e-05 20.7 0.0 5.6 1 1 3 6 6 6 6 Nucleoporin Nup120/160 CN_hydrolase PF00795.17 ETO29824.1 - 6e-27 94.1 0.0 1.4e-26 92.9 0.0 1.6 1 1 1 2 2 2 1 Carbon-nitrogen hydrolase zf-RanBP PF00641.13 ETO29825.1 - 3e-08 32.6 23.1 0.00017 20.5 0.6 3.6 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others DZR PF12773.2 ETO29825.1 - 2.5e-05 23.9 17.7 0.0052 16.5 6.5 2.8 1 1 1 2 2 2 2 Double zinc ribbon zf-ribbon_3 PF13248.1 ETO29825.1 - 7.2 5.9 15.7 0.053 12.7 1.0 3.0 3 0 0 3 3 3 0 zinc-ribbon domain Agenet PF05641.7 ETO29826.1 - 0.0012 18.9 1.5 0.0024 17.9 1.0 1.6 1 1 0 1 1 1 1 Agenet domain SH3_1 PF00018.23 ETO29826.1 - 0.037 13.4 0.6 0.55 9.6 0.1 2.0 1 1 1 2 2 2 0 SH3 domain DUF4633 PF15464.1 ETO29826.1 - 0.1 12.4 0.0 0.11 12.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) PDZ PF00595.19 ETO29827.1 - 0.00045 20.3 0.0 0.0014 18.7 0.0 1.8 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) C2 PF00168.25 ETO29827.1 - 0.037 13.8 0.0 0.082 12.7 0.0 1.6 1 0 0 1 1 1 0 C2 domain DUF1934 PF09148.5 ETO29828.1 - 0.017 14.8 1.1 0.063 12.9 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1934) PKD_channel PF08016.7 ETO29828.1 - 0.047 12.1 0.1 0.061 11.7 0.1 1.1 1 0 0 1 1 1 0 Polycystin cation channel GYF PF02213.11 ETO29829.1 - 7.3e-15 54.2 3.0 1.8e-14 53.0 1.7 1.9 2 0 0 2 2 2 1 GYF domain DUF4339 PF14237.1 ETO29829.1 - 0.014 14.9 0.1 0.031 13.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4339) VPS9 PF02204.13 ETO29831.1 - 1.3e-13 50.8 0.0 1.9e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain SAM_1 PF00536.25 ETO29832.1 - 2.1e-10 40.6 0.5 3.4e-10 39.9 0.4 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO29832.1 - 8.5e-10 38.3 0.4 1.2e-09 37.8 0.3 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 ETO29832.1 - 0.074 12.8 0.1 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain SET PF00856.23 ETO29832.1 - 0.14 12.4 0.5 0.18 12.1 0.4 1.2 1 0 0 1 1 1 0 SET domain DUF2718 PF10918.3 ETO29833.1 - 0.0034 17.4 0.9 0.0072 16.4 0.1 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF2718) IBB PF01749.15 ETO29834.1 - 7.6e-06 25.9 3.2 7.6e-06 25.9 2.2 1.8 3 0 0 3 3 3 1 Importin beta binding domain Arm PF00514.18 ETO29834.1 - 0.00076 19.2 0.2 0.044 13.6 0.0 2.9 1 1 1 2 2 2 1 Armadillo/beta-catenin-like repeat SPX PF03105.14 ETO29834.1 - 0.065 13.0 1.7 0.07 12.8 1.2 1.1 1 0 0 1 1 1 0 SPX domain DUF3399 PF11879.3 ETO29835.1 - 0.066 13.4 5.9 0.34 11.1 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3399) Ribosomal_L27 PF01016.14 ETO29836.1 - 0.81 9.5 6.0 0.4 10.4 0.2 2.4 2 0 0 2 2 2 0 Ribosomal L27 protein PNP_UDP_1 PF01048.15 ETO29837.1 - 1.6e-19 69.7 0.0 2.4e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily Caudo_TAP PF02413.12 ETO29837.1 - 0.021 15.0 2.0 0.63 10.2 0.1 2.5 1 1 1 2 2 2 0 Caudovirales tail fibre assembly protein RGS PF00615.14 ETO29838.1 - 0.00035 20.6 0.1 0.00066 19.7 0.0 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain Mus7 PF09462.5 ETO29838.1 - 0.011 14.5 2.8 0.018 13.9 1.9 1.3 1 0 0 1 1 1 0 Mus7/MMS22 family CENP-T PF15511.1 ETO29838.1 - 0.063 12.5 16.9 0.078 12.2 11.7 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CDC27 PF09507.5 ETO29838.1 - 0.78 8.8 25.2 1 8.5 17.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PAP_assoc PF03828.14 ETO29842.1 - 6.2e-13 48.4 2.6 7.2e-13 48.2 1.1 1.6 2 0 0 2 2 2 1 Cid1 family poly A polymerase tRNA_NucTransf2 PF09249.6 ETO29842.1 - 0.068 13.0 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 tRNA nucleotidyltransferase, second domain RAI1 PF08652.6 ETO29842.1 - 0.21 11.3 1.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 RAI1 like PD-(D/E)XK nuclease zf-RING_2 PF13639.1 ETO29843.1 - 1.4e-13 50.4 2.8 1.4e-13 50.4 1.9 2.0 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 ETO29843.1 - 3.6e-08 33.3 3.9 1.2e-07 31.7 2.7 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 ETO29843.1 - 2.3e-07 30.3 3.3 2.3e-07 30.3 2.3 2.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO29843.1 - 2.7e-07 30.5 4.3 2.7e-07 30.5 3.0 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO29843.1 - 1.5e-06 27.7 1.6 1.5e-06 27.7 1.1 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO29843.1 - 2.1e-05 24.1 1.6 2.1e-05 24.1 1.1 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 ETO29843.1 - 8.5e-05 22.3 1.5 0.00022 21.0 1.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FAM60A PF15396.1 ETO29843.1 - 0.0043 16.8 2.3 0.047 13.4 0.0 2.4 2 0 0 2 2 2 1 Protein Family FAM60A FANCL_C PF11793.3 ETO29843.1 - 0.041 13.8 3.5 0.24 11.3 2.4 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain FYDLN_acid PF09538.5 ETO29843.1 - 0.059 13.9 8.4 2.3 8.8 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) PHD PF00628.24 ETO29843.1 - 0.096 12.3 2.7 0.31 10.7 1.9 2.0 1 0 0 1 1 1 0 PHD-finger Menin PF05053.8 ETO29843.1 - 0.19 9.8 5.3 0.26 9.3 3.7 1.1 1 0 0 1 1 1 0 Menin Neur_chan_memb PF02932.11 ETO29843.1 - 0.41 10.5 5.3 2.6 7.8 3.6 2.3 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2457 PF10446.4 ETO29843.1 - 0.92 8.1 12.8 1.1 7.9 3.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) zf-RING_UBOX PF13445.1 ETO29843.1 - 1.1 9.0 7.2 0.19 11.4 0.2 2.9 3 0 0 3 3 3 0 RING-type zinc-finger RINGv PF12906.2 ETO29843.1 - 1.2 9.2 5.7 0.94 9.5 2.3 2.2 2 0 0 2 2 1 0 RING-variant domain DUF1754 PF08555.5 ETO29843.1 - 5.2 7.7 23.0 1.9 9.1 2.6 3.2 3 0 0 3 3 3 0 Eukaryotic family of unknown function (DUF1754) PTCB-BRCT PF12738.2 ETO29844.1 - 5.9e-09 35.6 0.0 2.2e-08 33.8 0.0 1.9 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 ETO29844.1 - 1.2e-06 28.5 0.7 3.1e-06 27.2 0.0 2.2 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain NIF PF03031.13 ETO29845.1 - 2.9e-14 53.0 0.4 5.4e-14 52.1 0.1 1.6 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase DUF2608 PF11019.3 ETO29845.1 - 0.15 11.0 0.1 0.23 10.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) zf-RING_2 PF13639.1 ETO29848.1 - 6.3e-15 54.7 7.1 9.4e-15 54.1 5.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 ETO29848.1 - 7.7e-10 38.7 2.2 1.6e-09 37.7 1.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 ETO29848.1 - 7.4e-08 31.9 3.9 1.2e-07 31.2 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO29848.1 - 2e-07 30.5 5.5 3.5e-07 29.7 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO29848.1 - 7.7e-07 29.0 6.6 1.2e-06 28.3 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO29848.1 - 7.8e-07 28.7 4.0 1.4e-06 27.8 2.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 ETO29848.1 - 0.0026 17.5 5.6 0.011 15.6 2.7 2.6 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Dicty_REP PF05086.7 ETO29848.1 - 0.019 12.7 9.1 0.025 12.3 6.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Astro_capsid PF03115.9 ETO29848.1 - 0.02 13.1 2.4 0.022 13.0 1.6 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor zf-RING-like PF08746.6 ETO29848.1 - 0.029 14.3 1.9 0.068 13.1 1.3 1.6 1 0 0 1 1 1 0 RING-like domain Daxx PF03344.10 ETO29848.1 - 0.14 10.5 8.4 0.16 10.3 5.8 1.0 1 0 0 1 1 1 0 Daxx Family zf-RING_4 PF14570.1 ETO29848.1 - 0.21 11.2 4.0 0.52 9.9 2.8 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF2457 PF10446.4 ETO29848.1 - 0.44 9.2 20.4 0.6 8.7 14.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RINGv PF12906.2 ETO29848.1 - 0.64 10.1 3.2 1.6 8.8 2.2 1.7 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 ETO29848.1 - 0.65 9.9 4.7 2.4 8.1 3.3 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Cwf_Cwc_15 PF04889.7 ETO29848.1 - 1 8.9 15.6 1.6 8.4 10.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.5 ETO29848.1 - 1.3 7.9 11.3 1.6 7.6 7.8 1.1 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.7 ETO29848.1 - 4.9 6.3 14.7 7.7 5.6 10.2 1.3 1 0 0 1 1 1 0 NOA36 protein Osteopontin PF00865.13 ETO29848.1 - 6.2 5.9 23.8 8.3 5.5 16.5 1.1 1 0 0 1 1 1 0 Osteopontin Nucleoplasmin PF03066.10 ETO29848.1 - 6.3 6.2 9.3 10 5.6 6.5 1.5 1 0 0 1 1 1 0 Nucleoplasmin RNA_pol_3_Rpc31 PF11705.3 ETO29848.1 - 6.6 6.5 17.0 9.1 6.1 11.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 GAGA PF09237.6 ETO29848.1 - 7 6.3 6.0 0.56 9.8 0.1 2.1 3 0 0 3 3 3 0 GAGA factor Neisseria_TspB PF05616.8 ETO29849.1 - 0.18 10.1 8.0 0.31 9.3 5.5 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Trypan_PARP PF05887.6 ETO29849.1 - 0.26 11.0 9.6 0.2 11.4 1.4 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) PLRV_ORF5 PF01690.12 ETO29849.1 - 4.8 6.2 14.8 5.7 5.9 1.2 2.1 2 0 0 2 2 2 0 Potato leaf roll virus readthrough protein CBP4 PF07960.6 ETO29850.1 - 0.053 13.1 0.5 0.098 12.2 0.4 1.4 1 0 0 1 1 1 0 CBP4 7TM_GPCR_Sru PF10322.4 ETO29851.1 - 0.003 16.6 0.8 0.0055 15.8 0.5 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sru AgrB PF04647.10 ETO29851.1 - 0.047 12.7 1.9 0.081 11.9 1.3 1.4 1 0 0 1 1 1 0 Accessory gene regulator B Matrix PF00661.16 ETO29851.1 - 0.071 11.4 3.6 0.74 8.0 0.5 2.1 2 0 0 2 2 2 0 Viral matrix protein DUF1361 PF07099.6 ETO29851.1 - 0.19 11.5 1.2 0.24 11.2 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1361) DUF2663 PF10864.3 ETO29851.1 - 0.47 10.6 7.4 3.3 7.9 5.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2663) DUF2500 PF10694.4 ETO29851.1 - 3.9 7.5 5.5 10 6.1 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2500) NYN PF01936.13 ETO29852.1 - 1.7e-06 28.3 1.2 3.4e-06 27.4 0.1 2.0 2 0 0 2 2 2 1 NYN domain DUF4271 PF14093.1 ETO29853.1 - 0.56 9.8 10.1 0.81 9.3 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) WD40 PF00400.27 ETO29855.1 - 9.4e-56 183.8 33.3 2.2e-12 46.3 0.2 7.3 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO29855.1 - 8.3e-12 44.0 12.6 0.00011 20.4 0.2 4.5 1 1 3 4 4 4 4 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO29855.1 - 2.9e-05 23.7 6.7 0.054 13.2 0.3 4.9 1 1 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region DUF3601 PF12208.3 ETO29855.1 - 4e-05 23.4 0.6 0.013 15.3 0.0 4.0 3 2 2 5 5 5 1 Domain of unknown function (DUF3601) Endotoxin_C PF03944.9 ETO29855.1 - 0.88 9.6 6.8 0.69 10.0 0.4 2.4 2 1 0 2 2 2 0 delta endotoxin Ank_2 PF12796.2 ETO29856.1 - 1.2e-07 31.9 0.1 1.9e-06 28.0 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO29856.1 - 4.3e-07 30.2 0.6 1.8e-06 28.2 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO29856.1 - 2e-06 27.4 0.4 8.1e-05 22.5 0.0 3.4 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.1 ETO29856.1 - 6e-06 26.3 0.2 2.5e-05 24.3 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 ETO29856.1 - 1.4e-05 24.6 0.0 9.1e-05 22.0 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeat SIR2 PF02146.12 ETO29858.1 - 3.4e-07 30.1 0.0 4.3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Sir2 family NARP1 PF12569.3 ETO29858.1 - 0.1 11.3 1.2 0.14 10.8 0.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Glutaredoxin PF00462.19 ETO29858.1 - 0.12 12.4 1.7 0.22 11.5 0.5 1.9 2 0 0 2 2 2 0 Glutaredoxin MMPL PF03176.10 ETO29859.1 - 6.5e-61 205.8 7.0 1.8e-30 105.8 0.5 2.4 2 1 0 2 2 2 2 MMPL family ACR_tran PF00873.14 ETO29859.1 - 0.017 12.6 10.5 0.23 8.8 3.9 2.3 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family HSP20 PF00011.16 ETO29860.1 - 5.5e-20 71.1 0.4 7.3e-20 70.7 0.3 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Flagellin_IN PF07196.8 ETO29861.1 - 0.044 13.7 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 Flagellin hook IN motif Skp1 PF01466.14 ETO29861.1 - 0.068 13.2 0.2 0.19 11.8 0.2 1.7 1 0 0 1 1 1 0 Skp1 family, dimerisation domain hNIFK_binding PF12196.3 ETO29861.1 - 0.14 11.6 3.2 0.31 10.4 2.2 1.7 1 1 0 1 1 1 0 FHA Ki67 binding domain of hNIFK Skp1 PF01466.14 ETO29862.1 - 0.00029 20.8 1.2 0.00042 20.2 0.8 1.4 1 1 0 1 1 1 1 Skp1 family, dimerisation domain YscJ_FliF PF01514.12 ETO29862.1 - 0.08 12.0 0.0 0.093 11.8 0.0 1.1 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family RE_TdeIII PF09520.5 ETO29862.1 - 0.094 11.9 0.1 0.096 11.9 0.1 1.0 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII WD40 PF00400.27 ETO29863.1 - 8.3e-144 462.9 43.7 2.6e-11 42.9 0.1 15.6 15 0 0 15 15 15 14 WD domain, G-beta repeat NACHT PF05729.7 ETO29863.1 - 3.9e-10 39.6 0.0 7.9e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DUF1258 PF06869.7 ETO29863.1 - 4.7e-10 38.9 12.5 0.2 10.6 0.1 8.0 5 3 4 9 9 9 3 Protein of unknown function (DUF1258) AAA_18 PF13238.1 ETO29863.1 - 1.1e-05 25.7 0.0 1.1e-05 25.7 0.0 4.3 4 1 0 4 4 4 1 AAA domain AAA_17 PF13207.1 ETO29863.1 - 6.8e-05 23.6 0.3 0.00075 20.3 0.0 3.1 2 0 0 2 2 2 1 AAA domain Pentapeptide PF00805.17 ETO29863.1 - 0.00032 19.8 0.6 0.00093 18.3 0.4 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) AAA_22 PF13401.1 ETO29863.1 - 0.00043 20.4 0.0 0.002 18.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETO29863.1 - 0.39 10.6 0.0 2.8 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Ras PF00071.17 ETO29864.1 - 7.1e-06 25.5 0.4 2.1e-05 23.9 0.3 1.9 1 1 0 1 1 1 1 Ras family F-box PF00646.28 ETO29864.1 - 7e-05 22.3 1.5 0.00016 21.1 1.1 1.6 1 0 0 1 1 1 1 F-box domain Miro PF08477.8 ETO29864.1 - 0.0042 17.5 0.2 0.011 16.1 0.1 1.8 1 1 0 1 1 1 1 Miro-like protein F-box-like PF12937.2 ETO29864.1 - 0.017 14.8 1.0 0.034 13.8 0.7 1.5 1 0 0 1 1 1 0 F-box-like NST1 PF13945.1 ETO29864.1 - 8.6 6.3 6.1 18 5.3 4.3 1.5 1 0 0 1 1 1 0 Salt tolerance down-regulator Ras PF00071.17 ETO29865.1 - 1.8e-07 30.6 0.1 2.5e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Zip PF02535.17 ETO29868.1 - 0.022 13.7 1.8 0.03 13.3 1.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter TraL PF07178.6 ETO29868.1 - 0.028 14.4 0.2 0.057 13.4 0.2 1.5 1 0 0 1 1 1 0 TraL protein DUF3341 PF11821.3 ETO29868.1 - 0.033 13.6 0.1 0.051 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) Neur_chan_memb PF02932.11 ETO29868.1 - 0.2 11.5 2.9 0.3 10.9 2.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PDR_CDR PF06422.7 ETO29868.1 - 7.2 6.3 6.6 1.2 8.7 0.4 2.5 2 0 0 2 2 2 0 CDR ABC transporter Methyltransf_21 PF05050.7 ETO29869.1 - 2.8e-10 40.3 0.1 6.2e-10 39.2 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase FkbM domain DUF3810 PF12725.2 ETO29869.1 - 0.053 12.4 0.0 0.079 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) P2X_receptor PF00864.14 ETO29870.1 - 1.8e-63 214.4 0.7 6.2e-63 212.7 0.5 1.7 1 1 0 1 1 1 1 ATP P2X receptor 2OG-FeII_Oxy_3 PF13640.1 ETO29871.1 - 6.7e-11 42.5 0.5 9.5e-11 42.0 0.4 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 ETO29871.1 - 2.2e-09 36.8 0.8 5.1e-09 35.6 0.4 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.8 ETO29871.1 - 6.9e-07 28.3 0.0 1.7e-06 27.0 0.0 1.6 2 0 0 2 2 2 1 Poxvirus C4/C10 protein 2OG-FeII_Oxy PF03171.15 ETO29871.1 - 0.0011 19.1 0.2 0.0019 18.4 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HIT PF01230.18 ETO29873.1 - 0.0026 18.2 0.1 0.077 13.5 0.0 2.4 2 0 0 2 2 2 1 HIT domain PUB PF09409.5 ETO29873.1 - 0.0098 15.6 0.5 0.0098 15.6 0.4 2.0 2 1 0 2 2 2 1 PUB domain PRK PF00485.13 ETO29874.1 - 8.5e-10 38.5 0.0 8.4e-06 25.4 0.0 2.2 1 1 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 ETO29874.1 - 2.7e-08 34.1 0.0 4.5e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO29874.1 - 3e-06 28.0 0.1 4.6e-06 27.4 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 ETO29874.1 - 0.013 15.4 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 ETO29874.1 - 0.063 12.1 0.1 0.12 11.2 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Thymidylate_kin PF02223.12 ETO29874.1 - 0.081 12.2 0.1 1.8 7.8 0.0 2.4 2 1 1 3 3 3 0 Thymidylate kinase Mad3_BUB1_I PF08311.7 ETO29875.1 - 1e-27 96.4 8.5 1.6e-27 95.8 5.9 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 FdtA PF05523.6 ETO29875.1 - 0.032 13.7 0.6 0.051 13.0 0.4 1.2 1 0 0 1 1 1 0 WxcM-like, C-terminal DUF262 PF03235.9 ETO29875.1 - 0.071 13.0 5.7 0.13 12.2 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF262 TUG-UBL1 PF11470.3 ETO29875.1 - 0.076 12.9 0.3 0.53 10.2 0.0 2.2 2 0 0 2 2 2 0 GLUT4 regulating protein TUG COG2 PF06148.6 ETO29875.1 - 0.17 11.7 0.3 0.17 11.7 0.2 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 UvrD-helicase PF00580.16 ETO29875.1 - 1.8 7.7 9.6 3.5 6.8 6.7 1.6 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain Herpes_DNAp_acc PF04929.7 ETO29876.1 - 0.37 9.7 0.0 0.37 9.7 0.0 2.1 1 1 0 2 2 2 0 Herpes DNA replication accessory factor Nop14 PF04147.7 ETO29876.1 - 1.1 7.1 51.7 0.057 11.3 21.3 2.1 2 0 0 2 2 2 0 Nop14-like family Radial_spoke PF04712.7 ETO29876.1 - 1.2 7.7 36.1 0.73 8.5 8.6 2.4 2 0 0 2 2 2 0 Radial spokehead-like protein Prothymosin PF03247.9 ETO29876.1 - 3.1 8.0 86.2 0.32 11.1 2.9 3.5 3 0 0 3 3 3 0 Prothymosin/parathymosin family DUF2457 PF10446.4 ETO29876.1 - 4.9 5.7 49.1 1.6 7.3 13.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2457) TRAP_alpha PF03896.11 ETO29876.1 - 9.2 5.1 32.8 0.68 8.8 9.2 2.9 3 0 0 3 3 3 0 Translocon-associated protein (TRAP), alpha subunit zf-RanBP PF00641.13 ETO29877.1 - 2.4e-05 23.3 5.0 6e-05 22.0 3.5 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DZR PF12773.2 ETO29877.1 - 0.052 13.3 2.3 0.098 12.4 1.6 1.4 1 0 0 1 1 1 0 Double zinc ribbon Peptidase_S49 PF01343.13 ETO29878.1 - 1e-19 70.8 0.0 1.8e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S49 YlqD PF11068.3 ETO29878.1 - 0.85 9.6 6.9 0.098 12.6 1.6 1.7 2 0 0 2 2 2 0 YlqD protein MatC_N PF07158.6 ETO29880.1 - 0.3 10.8 8.2 0.6 9.9 5.7 1.7 1 1 0 1 1 1 0 Dicarboxylate carrier protein MatC N-terminus DUF872 PF05915.7 ETO29880.1 - 0.89 9.4 4.9 11 5.8 0.5 2.4 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) UxaC PF02614.9 ETO29881.1 - 0.023 13.3 0.4 0.025 13.2 0.3 1.1 1 0 0 1 1 1 0 Glucuronate isomerase DUF3439 PF11921.3 ETO29882.1 - 0.003 17.2 6.4 0.078 12.7 0.7 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3439) DUF305 PF03713.8 ETO29882.1 - 0.0064 16.3 16.3 0.046 13.5 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF305) OPA3 PF07047.7 ETO29882.1 - 0.15 11.8 13.9 0.42 10.3 0.1 2.7 2 1 0 2 2 2 0 Optic atrophy 3 protein (OPA3) Mucin PF01456.12 ETO29882.1 - 0.31 10.7 28.3 0.51 10.1 10.9 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein FtsL PF04999.8 ETO29882.1 - 0.42 10.3 7.7 1.3 8.7 5.3 2.0 1 1 0 1 1 1 0 Cell division protein FtsL WD40 PF00400.27 ETO29883.1 - 4e-18 64.5 0.3 1.4e-10 40.6 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO29883.1 - 0.00045 18.4 0.1 0.23 9.5 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO29883.1 - 0.0094 14.7 0.5 0.065 11.9 0.1 1.9 1 1 1 2 2 2 1 Nup133 N terminal like DUF629 PF04780.7 ETO29884.1 - 0.061 11.8 0.0 0.071 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) PUB PF09409.5 ETO29884.1 - 0.072 12.8 0.6 0.12 12.1 0.4 1.4 1 0 0 1 1 1 0 PUB domain DUF1077 PF06417.7 ETO29884.1 - 0.99 8.7 5.0 0.98 8.7 2.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1077) Kelch_1 PF01344.20 ETO29886.1 - 0.024 14.1 3.2 0.76 9.3 0.0 3.3 3 0 0 3 3 3 0 Kelch motif Kelch_6 PF13964.1 ETO29886.1 - 0.099 12.8 5.1 2.3 8.5 0.0 3.9 4 0 0 4 4 4 0 Kelch motif Tom22 PF04281.8 ETO29887.1 - 1.2 8.6 6.1 0.24 10.9 0.8 2.2 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Pro_3_hydrox_C PF05373.6 ETO29889.1 - 0.35 10.9 2.6 3.7 7.6 0.0 3.3 3 1 0 3 3 3 0 L-proline 3-hydroxylase, C-terminal NUDIX PF00293.23 ETO29890.1 - 1.4e-08 34.4 0.0 1.5e-05 24.6 0.0 2.3 2 0 0 2 2 2 2 NUDIX domain RasGEF PF00617.14 ETO29890.1 - 0.0013 18.4 0.0 0.0013 18.4 0.0 2.1 3 0 0 3 3 3 1 RasGEF domain TMEM154 PF15102.1 ETO29890.1 - 0.0069 16.1 0.5 0.015 15.0 0.3 1.5 1 0 0 1 1 1 1 TMEM154 protein family DUF3357 PF11837.3 ETO29890.1 - 0.026 14.3 0.0 0.071 12.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) OAD_gamma PF04277.8 ETO29890.1 - 7.1 7.0 6.5 0.46 10.8 0.6 2.0 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain zf-TRAF PF02176.13 ETO29892.1 - 7.1e-06 26.3 2.9 7.1e-06 26.3 2.0 2.8 3 0 0 3 3 3 1 TRAF-type zinc finger DUF1664 PF07889.7 ETO29892.1 - 0.98 9.2 8.1 0.35 10.6 3.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF334 PF03904.8 ETO29892.1 - 2.6 7.3 15.0 26 4.0 9.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF334) DUF730 PF05325.6 ETO29892.1 - 4.6 7.0 9.6 11 5.8 0.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF730) Ycf1 PF05758.7 ETO29893.1 - 4.7e-06 24.6 7.6 7.7e-06 23.9 5.3 1.3 1 0 0 1 1 1 1 Ycf1 Daxx PF03344.10 ETO29893.1 - 8.6e-05 21.2 28.3 0.00013 20.6 19.6 1.2 1 0 0 1 1 1 1 Daxx Family DUF1510 PF07423.6 ETO29893.1 - 0.00055 19.3 20.9 0.00055 19.3 14.5 1.6 2 0 0 2 2 1 1 Protein of unknown function (DUF1510) Nop14 PF04147.7 ETO29893.1 - 0.0012 16.8 29.0 0.0016 16.4 20.1 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 ETO29893.1 - 0.0014 16.7 18.2 0.002 16.2 12.6 1.1 1 0 0 1 1 1 1 CDC45-like protein Caldesmon PF02029.10 ETO29893.1 - 0.0018 16.7 24.8 0.0027 16.2 17.2 1.2 1 0 0 1 1 1 1 Caldesmon MIP-T3 PF10243.4 ETO29893.1 - 0.0079 14.7 19.2 0.012 14.1 13.3 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Dynamin_N PF00350.18 ETO29893.1 - 0.021 14.6 2.2 0.044 13.5 1.5 1.6 1 0 0 1 1 1 0 Dynamin family SDA1 PF05285.7 ETO29893.1 - 0.024 13.9 27.1 0.039 13.2 18.8 1.4 1 0 0 1 1 1 0 SDA1 DDHD PF02862.12 ETO29893.1 - 0.069 12.9 8.7 0.13 12.0 6.0 1.5 1 0 0 1 1 1 0 DDHD domain Paf1 PF03985.8 ETO29893.1 - 0.13 11.0 32.9 0.27 9.9 22.8 1.5 1 0 0 1 1 1 0 Paf1 CENP-T PF15511.1 ETO29893.1 - 0.13 11.4 17.9 0.19 10.9 12.4 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Astro_capsid PF03115.9 ETO29893.1 - 0.22 9.7 6.3 0.3 9.2 4.4 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor RRN3 PF05327.6 ETO29893.1 - 0.33 9.0 13.5 0.45 8.5 9.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Hid1 PF12722.2 ETO29893.1 - 0.52 7.9 12.1 0.71 7.4 8.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Mpp10 PF04006.7 ETO29893.1 - 0.81 7.9 37.8 0.17 10.2 23.5 1.7 2 0 0 2 2 2 0 Mpp10 protein VID27 PF08553.5 ETO29893.1 - 1.5 6.9 31.7 4.7 5.3 22.0 1.6 1 1 0 1 1 1 0 VID27 cytoplasmic protein zf-HIT PF04438.11 ETO29893.1 - 2.1 8.0 6.5 4.9 6.8 4.5 1.6 1 0 0 1 1 1 0 HIT zinc finger HSP90 PF00183.13 ETO29893.1 - 4.5 5.5 28.2 10 4.4 19.6 1.6 1 0 0 1 1 1 0 Hsp90 protein Pilt PF15453.1 ETO29893.1 - 4.9 6.7 13.5 7.9 6.0 9.3 1.3 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Zip PF02535.17 ETO29893.1 - 8.4 5.2 10.8 13 4.6 7.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4045 PF13254.1 ETO29893.1 - 9.7 5.3 12.6 16 4.6 8.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF3545 PF12065.3 ETO29896.1 - 0.00042 19.9 2.7 0.00049 19.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3545) Nudix_N PF12535.3 ETO29896.1 - 0.047 13.1 8.0 4.8 6.7 0.2 4.1 3 1 0 3 3 3 0 Hydrolase of X-linked nucleoside diphosphate N terminal DivIC PF04977.10 ETO29896.1 - 0.069 12.6 0.1 0.069 12.6 0.1 5.5 5 2 1 6 6 6 0 Septum formation initiator HU-DNA_bdg PF14848.1 ETO29896.1 - 0.081 12.6 0.1 0.081 12.6 0.0 3.1 4 1 1 5 5 5 0 DNA-binding domain SWIRM PF04433.12 ETO29896.1 - 0.086 12.9 1.3 0.3 11.2 0.3 2.2 2 0 0 2 2 2 0 SWIRM domain HALZ PF02183.13 ETO29896.1 - 0.24 11.1 0.2 0.24 11.1 0.1 5.3 5 0 0 5 5 5 0 Homeobox associated leucine zipper DUF3199 PF11436.3 ETO29897.1 - 0.0025 17.6 0.3 0.0077 16.0 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3199) WD40 PF00400.27 ETO29898.1 - 4.7e-55 181.6 20.1 1.9e-11 43.3 0.7 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO29898.1 - 2.5e-08 32.5 0.5 0.15 10.1 0.0 4.8 1 1 2 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO29898.1 - 0.0087 14.8 12.9 0.93 8.1 0.1 3.7 1 1 3 4 4 4 3 Nup133 N terminal like Adaptin_N PF01602.15 ETO29899.1 - 2.7e-34 118.3 0.6 3.6e-34 117.9 0.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.17 ETO29899.1 - 0.00088 19.1 2.6 0.46 10.6 0.0 5.0 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.1 ETO29899.1 - 0.0019 18.4 2.3 0.075 13.3 0.0 3.9 2 2 0 3 3 3 1 HEAT repeats MMS19_C PF12460.3 ETO29899.1 - 0.016 13.9 0.5 0.11 11.1 0.2 2.4 1 1 2 3 3 3 0 RNAPII transcription regulator C-terminal ANF_receptor PF01094.23 ETO29899.1 - 0.021 13.6 0.0 0.03 13.1 0.0 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region Dicty_REP PF05086.7 ETO29901.1 - 0.002 16.0 0.9 0.0024 15.7 0.7 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 ETO29901.1 - 3.1 7.5 8.9 3.9 7.2 2.4 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Rap_GAP PF02145.10 ETO29902.1 - 7.7e-15 54.7 1.2 5.8e-11 42.1 0.0 3.2 3 0 0 3 3 3 2 Rap/ran-GAP DUF4175 PF13779.1 ETO29903.1 - 0.076 10.7 9.7 0.095 10.3 6.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF1675 PF07897.6 ETO29903.1 - 0.099 12.4 19.3 0.12 12.1 13.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Dsh_C PF12316.3 ETO29903.1 - 0.19 11.8 19.0 0.26 11.3 13.2 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal SprA-related PF12118.3 ETO29903.1 - 1.1 8.5 21.7 1.2 8.4 15.0 1.1 1 0 0 1 1 1 0 SprA-related family RR_TM4-6 PF06459.7 ETO29903.1 - 5.8 6.7 18.2 7.2 6.4 12.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MIP-T3 PF10243.4 ETO29903.1 - 6.7 5.0 38.3 8 4.7 26.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SRP-alpha_N PF04086.8 ETO29903.1 - 9.3 5.5 32.7 11 5.2 22.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CK_II_beta PF01214.13 ETO29904.1 - 1.4e-27 96.4 0.0 4.1e-27 94.8 0.0 1.7 1 1 1 2 2 2 1 Casein kinase II regulatory subunit zf-TRAF PF02176.13 ETO29905.1 - 0.0014 18.9 3.6 0.0014 18.9 2.5 2.8 2 1 0 2 2 2 1 TRAF-type zinc finger Cyclin_C PF02984.14 ETO29907.1 - 3.7e-17 62.3 0.5 5.1e-17 61.9 0.3 1.2 1 0 0 1 1 1 1 Cyclin, C-terminal domain DSPc PF00782.15 ETO29908.1 - 0.00063 19.3 0.7 0.0094 15.5 0.1 2.7 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain zf-C3HC4_2 PF13923.1 ETO29909.1 - 0.018 15.0 0.1 0.04 13.9 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HSP70 PF00012.15 ETO29909.1 - 0.042 11.7 7.1 0.045 11.6 4.9 1.2 1 0 0 1 1 1 0 Hsp70 protein zf-RING_UBOX PF13445.1 ETO29909.1 - 0.076 12.7 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Daxx PF03344.10 ETO29909.1 - 0.11 10.9 24.4 0.0076 14.8 13.7 1.4 2 0 0 2 2 2 0 Daxx Family CytochromB561_N PF09786.4 ETO29909.1 - 0.14 10.5 2.4 0.16 10.4 1.7 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Bud13 PF09736.4 ETO29909.1 - 0.32 11.2 18.6 0.1 12.8 10.1 2.1 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex DUF740 PF05340.7 ETO29909.1 - 0.43 8.8 11.8 0.65 8.2 8.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Spore_coat_CotO PF14153.1 ETO29909.1 - 1.3 8.4 20.6 0.3 10.5 11.5 1.9 2 0 0 2 2 2 0 Spore coat protein CotO Ycf1 PF05758.7 ETO29909.1 - 2.4 5.7 14.9 3.3 5.2 10.3 1.2 1 0 0 1 1 1 0 Ycf1 Pox_Ag35 PF03286.9 ETO29909.1 - 2.5 7.5 15.3 4.8 6.6 10.6 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CWC25 PF12542.3 ETO29909.1 - 5.5 7.4 19.9 2.1 8.8 11.0 2.4 2 1 0 2 2 2 0 Pre-mRNA splicing factor Hid1 PF12722.2 ETO29909.1 - 5.8 4.4 10.4 6.6 4.2 7.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Parvo_coat PF00740.13 ETO29909.1 - 6.7 5.5 6.0 8.5 5.1 4.2 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Sulfotransfer_1 PF00685.22 ETO29910.1 - 0.0018 17.5 0.1 0.0031 16.8 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase domain MIR PF02815.14 ETO29911.1 - 1.1e-13 51.2 0.8 1.3e-12 47.6 0.4 2.8 1 1 1 2 2 2 1 MIR domain IL15 PF02372.10 ETO29911.1 - 0.014 15.1 1.6 0.014 15.1 1.1 1.8 1 1 1 2 2 2 0 Interleukin 15 MDFI PF15316.1 ETO29911.1 - 3.5 7.5 11.5 12 5.8 3.2 2.4 2 0 0 2 2 2 0 MyoD family inhibitor DAGAT PF03982.8 ETO29912.1 - 0.0095 14.6 2.1 0.013 14.2 0.7 1.6 2 0 0 2 2 2 1 Diacylglycerol acyltransferase ACI44 PF15270.1 ETO29913.1 - 4 7.4 7.4 0.3 11.0 0.5 2.7 4 0 0 4 4 4 0 Metallo-carboxypeptidase inhibitor BRF1 PF07741.8 ETO29914.1 - 0.01 16.0 2.7 0.017 15.3 0.5 1.9 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Ctr PF04145.10 ETO29914.1 - 0.013 15.5 0.2 0.72 9.8 0.0 2.1 2 0 0 2 2 2 0 Ctr copper transporter family Ribosomal_L6e PF01159.14 ETO29914.1 - 0.039 14.1 0.4 0.066 13.4 0.3 1.4 1 0 0 1 1 1 0 Ribosomal protein L6e Z1 PF10593.4 ETO29914.1 - 0.066 12.4 1.7 0.095 11.8 1.2 1.3 1 0 0 1 1 1 0 Z1 domain Cut8_N PF14482.1 ETO29914.1 - 1 9.4 9.8 11 6.1 3.1 2.4 2 0 0 2 2 2 0 Cut8 proteasome-binding domain Zip PF02535.17 ETO29914.1 - 3.4 6.6 4.8 5.3 5.9 3.4 1.5 1 1 0 1 1 1 0 ZIP Zinc transporter YWFCY PF14293.1 ETO29915.1 - 0.55 10.1 4.4 1.4 8.8 3.1 1.6 1 0 0 1 1 1 0 YWFCY protein 4F5 PF04419.9 ETO29916.1 - 0.016 15.9 7.6 0.016 15.9 5.3 2.3 2 1 1 3 3 3 0 4F5 protein family TFIIF_alpha PF05793.7 ETO29916.1 - 0.02 13.2 38.8 0.023 13.1 26.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 ETO29916.1 - 0.1 10.5 40.1 0.12 10.2 27.8 1.0 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 ETO29916.1 - 6.1 5.1 29.4 7.2 4.9 20.4 1.2 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 ETO29916.1 - 7.7 5.6 36.6 11 5.1 25.4 1.3 1 0 0 1 1 1 0 SDA1 Ricin_B_lectin PF00652.17 ETO29917.1 - 1.2e-10 41.5 12.9 1.1e-07 31.9 2.8 2.7 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain NIF PF03031.13 ETO29918.1 - 2.8e-19 69.3 0.4 8.6e-14 51.5 0.0 2.7 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase BRCT PF00533.21 ETO29918.1 - 1.4e-07 31.5 0.1 4e-07 30.0 0.1 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 ETO29918.1 - 8.3e-07 28.7 0.0 2.2e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain Biotin_lipoyl_2 PF13533.1 ETO29919.1 - 1.4e-06 27.8 0.0 3.6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Biotin-lipoyl like Biotin_lipoyl PF00364.17 ETO29919.1 - 6.1e-05 22.5 0.1 0.0001 21.8 0.1 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_2 PF12700.2 ETO29919.1 - 0.002 17.3 0.9 0.13 11.4 0.2 2.1 1 1 1 2 2 2 2 HlyD family secretion protein LolA PF03548.10 ETO29919.1 - 0.072 12.6 2.2 0.072 12.7 0.5 1.7 2 0 0 2 2 2 0 Outer membrane lipoprotein carrier protein LolA UPF0233 PF06781.7 ETO29919.1 - 0.12 12.0 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) LicD PF04991.8 ETO29920.1 - 0.029 14.4 0.0 0.029 14.4 0.0 2.3 2 1 0 2 2 2 0 LicD family DUF778 PF05608.7 ETO29921.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF778) RNase_H2_suC PF08615.6 ETO29921.1 - 0.27 11.0 2.6 0.26 11.1 0.9 1.6 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF912 PF06024.7 ETO29922.1 - 0.017 15.1 1.3 0.038 14.0 0.9 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Secretin_N_2 PF07655.8 ETO29922.1 - 4.1 7.8 12.6 9.5 6.6 8.7 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain Pribosyltran_N PF13793.1 ETO29923.1 - 0.096 12.4 0.0 0.59 9.8 0.0 2.3 2 0 0 2 2 2 0 N-terminal domain of ribose phosphate pyrophosphokinase IRK PF01007.15 ETO29924.1 - 6.7e-27 94.1 2.2 2.2e-25 89.1 1.5 2.3 1 1 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 ETO29924.1 - 1.5e-05 24.5 9.7 3.7e-05 23.3 6.7 1.7 1 0 0 1 1 1 1 Ion channel Pentapeptide PF00805.17 ETO29925.1 - 7.1e-65 213.4 37.9 3.3e-10 38.9 0.3 11.5 3 2 10 14 14 14 12 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO29925.1 - 1.9e-56 187.7 91.9 8.3e-13 47.9 5.0 7.4 3 2 5 8 8 8 7 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 ETO29925.1 - 1.5e-40 136.8 54.6 1.2e-06 28.3 2.6 10.7 3 2 7 11 11 11 10 Pentapeptide repeats (9 copies) NPV_P10 PF05531.7 ETO29925.1 - 0.0011 19.1 1.1 0.0011 19.1 0.8 3.3 2 1 1 3 3 3 1 Nucleopolyhedrovirus P10 protein Tup_N PF08581.5 ETO29925.1 - 0.0099 16.0 10.4 0.042 14.0 7.2 2.1 1 0 0 1 1 1 1 Tup N-terminal LCM PF04072.9 ETO29925.1 - 0.066 12.7 0.1 0.41 10.1 0.0 2.2 2 0 0 2 2 2 0 Leucine carboxyl methyltransferase IncA PF04156.9 ETO29925.1 - 0.18 11.3 18.2 0.48 9.9 12.6 1.7 1 0 0 1 1 1 0 IncA protein Herpes_capsid PF06112.6 ETO29925.1 - 1.1 9.2 10.9 2.9 7.9 7.6 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DivIC PF04977.10 ETO29925.1 - 9.2 5.8 14.4 13 5.3 3.8 2.8 1 1 1 2 2 2 0 Septum formation initiator DUF2976 PF11190.3 ETO29926.1 - 0.29 10.6 6.8 1.8 8.1 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2976) Cpn60_TCP1 PF00118.19 ETO29927.1 - 3.9e-40 137.8 0.1 4.6e-40 137.6 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.19 ETO29928.1 - 5.3e-76 256.1 0.4 6.2e-76 255.9 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Glucosamine_iso PF01182.15 ETO29929.1 - 0.00012 21.9 0.0 0.00025 20.8 0.0 1.5 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase YwiC PF14256.1 ETO29931.1 - 0.49 10.4 1.8 1.6 8.8 0.4 2.4 3 0 0 3 3 3 0 YwiC-like protein Cas_Csy4 PF09618.5 ETO29932.1 - 0.02 14.7 1.2 0.027 14.2 0.8 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) WGR PF05406.10 ETO29932.1 - 0.87 9.5 4.3 4.5 7.2 0.0 2.8 2 1 1 3 3 3 0 WGR domain DOMON PF03351.12 ETO29935.1 - 0.0004 20.2 0.3 0.00079 19.3 0.2 1.5 1 0 0 1 1 1 1 DOMON domain Caps_assemb_Wzi PF14052.1 ETO29935.1 - 0.0078 15.1 0.1 0.01 14.7 0.1 1.1 1 0 0 1 1 1 1 Capsule assembly protein Wzi V-SNARE PF05008.10 ETO29936.1 - 1.8e-12 47.2 2.5 1.8e-12 47.2 1.7 2.3 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 ETO29936.1 - 7e-10 38.8 3.5 7e-10 38.8 2.4 1.8 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 ETO29936.1 - 0.0084 15.7 0.8 0.025 14.2 0.1 2.1 2 0 0 2 2 2 1 Sec20 TroA PF01297.12 ETO29936.1 - 0.011 14.9 0.1 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Periplasmic solute binding protein family PEP-utilisers_N PF05524.8 ETO29936.1 - 0.11 12.2 2.3 0.19 11.5 0.5 1.9 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Syntaxin_2 PF14523.1 ETO29936.1 - 0.7 9.9 12.2 5.5 7.0 0.3 2.3 2 0 0 2 2 2 0 Syntaxin-like protein DUF1664 PF07889.7 ETO29936.1 - 1.9 8.2 5.5 4.7 7.0 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) SseC PF04888.7 ETO29936.1 - 3 7.0 5.5 4.1 6.6 3.8 1.3 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family Shisa PF13908.1 ETO29938.1 - 0.015 15.5 1.0 0.032 14.3 0.0 2.0 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator DUF3753 PF12575.3 ETO29938.1 - 0.21 11.4 4.8 0.81 9.5 3.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) p450 PF00067.17 ETO29939.1 - 1.3e-31 109.6 0.0 1.7e-31 109.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2207 PF09972.4 ETO29940.1 - 0.054 12.0 0.5 0.074 11.6 0.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2899 PF11449.3 ETO29940.1 - 0.058 12.5 0.1 0.084 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2899) DUF4064 PF13273.1 ETO29940.1 - 0.14 12.2 1.7 0.19 11.8 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) ADH_zinc_N PF00107.21 ETO29941.1 - 1.1e-25 89.7 0.0 3.1e-25 88.2 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETO29942.1 - 4.2e-09 36.1 0.5 2.6e-08 33.5 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain zf-RanBP PF00641.13 ETO29942.1 - 0.00016 20.6 7.9 0.0004 19.4 5.5 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others YajC PF02699.10 ETO29943.1 - 0.12 12.0 0.8 0.35 10.5 0.5 1.7 1 0 0 1 1 1 0 Preprotein translocase subunit CENP-B_dimeris PF09026.5 ETO29943.1 - 0.58 10.4 14.5 3.4 7.9 3.5 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.7 ETO29943.1 - 0.83 9.3 46.6 0.58 9.8 9.1 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein WD40 PF00400.27 ETO29944.1 - 8.4e-63 206.1 6.4 5.6e-13 48.2 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat PD40 PF07676.7 ETO29944.1 - 2.6e-06 26.9 4.9 0.13 11.9 0.0 5.4 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 ETO29944.1 - 6.7e-05 22.0 0.1 0.25 10.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1258) SGL PF08450.7 ETO29944.1 - 0.00045 19.6 0.0 0.0086 15.4 0.0 2.6 1 1 1 3 3 3 1 SMP-30/Gluconolaconase/LRE-like region Cytochrom_D1 PF02239.11 ETO29944.1 - 0.0024 16.2 0.1 0.47 8.6 0.0 2.8 2 1 1 3 3 3 2 Cytochrome D1 heme domain DPPIV_N PF00930.16 ETO29944.1 - 0.0085 14.7 0.0 0.28 9.7 0.0 2.9 2 1 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Coatomer_WDAD PF04053.9 ETO29944.1 - 0.0097 14.7 0.0 0.74 8.5 0.0 2.3 1 1 1 2 2 2 1 Coatomer WD associated region GSDH PF07995.6 ETO29944.1 - 0.022 13.8 0.0 0.52 9.3 0.0 2.7 2 0 0 2 2 2 0 Glucose / Sorbosone dehydrogenase IKI3 PF04762.7 ETO29944.1 - 0.032 12.0 0.3 0.68 7.6 0.0 2.3 1 1 1 2 2 2 0 IKI3 family Proteasome_A_N PF10584.4 ETO29944.1 - 0.051 12.8 6.4 22 4.4 0.0 4.9 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Nbas_N PF15492.1 ETO29944.1 - 0.054 12.5 0.1 0.56 9.2 0.0 2.4 1 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal TFIIIC_delta PF12657.2 ETO29944.1 - 2.7 7.6 9.7 2.4 7.8 0.3 4.3 2 1 3 5 5 5 0 Transcription factor IIIC subunit delta N-term Kelch_6 PF13964.1 ETO29945.1 - 3.5e-08 33.2 1.7 0.0012 18.9 0.0 3.8 3 1 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 ETO29945.1 - 0.00057 19.3 2.1 0.14 11.7 0.1 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 ETO29945.1 - 0.00084 19.2 1.1 0.075 13.0 0.0 3.9 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 ETO29945.1 - 0.037 14.1 0.1 1.2 9.3 0.0 3.3 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO29945.1 - 0.1 12.4 3.5 4 7.3 0.1 3.5 3 0 0 3 3 3 0 Kelch motif TPR_12 PF13424.1 ETO29947.1 - 1.3e-28 98.7 3.6 2.1e-20 72.4 0.4 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO29947.1 - 1.6e-18 66.0 0.0 2e-08 33.8 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO29947.1 - 1.6e-16 58.7 3.0 2.5e-08 33.0 0.1 3.5 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO29947.1 - 2.5e-13 48.7 10.7 1.5e-07 30.6 0.6 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO29947.1 - 8.1e-13 47.8 6.5 5.2e-06 26.0 0.2 3.1 1 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 ETO29947.1 - 1.9e-11 43.0 6.3 1.3e-06 27.7 0.5 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO29947.1 - 2.9e-09 36.1 7.8 3.5e-05 23.3 0.1 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO29947.1 - 3e-05 23.8 0.7 0.51 10.6 0.1 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO29947.1 - 0.00023 21.7 0.1 0.085 13.5 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO29947.1 - 0.00033 20.9 2.0 0.058 13.8 0.1 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat PPR PF01535.15 ETO29947.1 - 0.0012 18.6 0.1 0.7 10.0 0.0 3.1 3 0 0 3 3 3 1 PPR repeat TPR_14 PF13428.1 ETO29947.1 - 0.0052 17.3 0.0 2.7 8.8 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 ETO29947.1 - 0.011 15.5 6.1 0.078 12.8 0.8 3.1 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain DUF627 PF04781.7 ETO29947.1 - 0.068 12.7 0.2 0.068 12.7 0.1 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF627) Apc3 PF12895.2 ETO29947.1 - 0.085 13.0 4.8 0.1 12.7 2.3 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Sel1 PF08238.7 ETO29947.1 - 0.18 12.4 4.2 0.39 11.4 0.2 2.6 2 0 0 2 2 2 0 Sel1 repeat TPR_3 PF07720.7 ETO29947.1 - 3.2 7.6 8.9 1.2 8.9 1.7 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat WBP-1 PF11669.3 ETO29948.1 - 0.0019 18.2 2.7 0.0019 18.2 1.9 2.9 2 1 1 3 3 3 1 WW domain-binding protein 1 DUF1980 PF09323.5 ETO29948.1 - 0.0036 17.0 3.1 0.0058 16.3 2.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1980) Saw1 PF11561.3 ETO29951.1 - 0.13 11.6 8.6 0.14 11.5 5.2 1.7 1 1 0 1 1 1 0 Single strand annealing-weakened 1 NOA36 PF06524.7 ETO29951.1 - 0.57 9.3 6.1 0.98 8.6 4.2 1.3 1 0 0 1 1 1 0 NOA36 protein DUF2360 PF10152.4 ETO29952.1 - 7.1e-05 23.1 0.8 7.1e-05 23.1 0.6 2.3 2 1 0 2 2 2 1 Predicted coiled-coil domain-containing protein (DUF2360) UBA PF00627.26 ETO29953.1 - 0.0027 17.5 0.3 0.0059 16.4 0.2 1.5 1 0 0 1 1 1 1 UBA/TS-N domain PDZ PF00595.19 ETO29953.1 - 0.077 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) BRF1 PF07741.8 ETO29953.1 - 1.7 8.9 11.2 0.18 12.0 2.8 2.4 2 0 0 2 2 2 0 Brf1-like TBP-binding domain JmjC PF02373.17 ETO29954.1 - 4.6e-07 30.0 0.1 4.6e-07 30.0 0.1 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 ETO29954.1 - 3.2e-06 26.8 1.0 5.3e-06 26.1 0.7 1.3 1 0 0 1 1 1 1 Cupin-like domain GPI PF06560.6 ETO29954.1 - 0.071 12.1 0.1 0.16 10.9 0.0 1.6 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) ERAP1_C PF11838.3 ETO29955.1 - 2.7e-21 76.1 0.4 7.2e-12 45.1 0.1 2.1 2 0 0 2 2 2 2 ERAP1-like C-terminal domain DUF1049 PF06305.6 ETO29955.1 - 0.0052 16.2 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1049) DUF4577 PF15145.1 ETO29955.1 - 0.017 15.0 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) Protocadherin PF08374.6 ETO29955.1 - 0.019 14.6 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 Protocadherin TMEM154 PF15102.1 ETO29955.1 - 0.019 14.6 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Oxidored_q2 PF00420.19 ETO29955.1 - 0.035 13.7 0.1 0.093 12.3 0.0 1.7 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L IncA PF04156.9 ETO29955.1 - 0.045 13.3 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 IncA protein Herpes_gE PF02480.11 ETO29955.1 - 0.071 11.3 0.0 0.097 10.9 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Rifin_STEVOR PF02009.11 ETO29955.1 - 0.074 12.6 0.3 0.14 11.7 0.2 1.4 1 0 0 1 1 1 0 Rifin/stevor family HemY_N PF07219.8 ETO29955.1 - 0.11 12.0 0.7 0.27 10.7 0.3 1.7 2 0 0 2 2 2 0 HemY protein N-terminus PUB PF09409.5 ETO29956.1 - 1.1e-09 37.8 0.5 2.2e-09 36.9 0.3 1.5 1 0 0 1 1 1 1 PUB domain Ras PF00071.17 ETO29957.1 - 5.6e-52 175.3 1.2 1.3e-50 170.9 0.2 2.7 2 1 0 2 2 2 1 Ras family Miro PF08477.8 ETO29957.1 - 3.3e-14 53.3 0.0 1.2e-13 51.6 0.0 2.0 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO29957.1 - 1.6e-06 27.4 0.2 2.8e-05 23.4 0.1 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETO29957.1 - 0.041 13.8 0.0 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Laminin_II PF06009.7 ETO29958.1 - 0.001 18.8 3.6 0.001 18.8 2.5 2.3 1 1 1 2 2 2 1 Laminin Domain II HALZ PF02183.13 ETO29958.1 - 0.0026 17.4 4.3 0.0026 17.4 3.0 3.6 4 1 0 4 4 3 1 Homeobox associated leucine zipper AAA_13 PF13166.1 ETO29958.1 - 0.0067 14.9 16.7 0.0092 14.4 11.6 1.1 1 0 0 1 1 1 1 AAA domain ADPrib_exo_Tox PF03496.9 ETO29958.1 - 0.016 14.4 2.8 0.035 13.3 1.9 1.5 1 1 0 1 1 1 0 ADP-ribosyltransferase exoenzyme DUF3450 PF11932.3 ETO29958.1 - 0.02 14.1 23.3 0.12 11.5 4.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) WXG100 PF06013.7 ETO29958.1 - 0.025 14.5 0.9 0.025 14.5 0.6 3.6 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Tim44 PF04280.10 ETO29958.1 - 0.039 13.9 0.8 0.039 13.9 0.6 2.2 1 1 1 2 2 2 0 Tim44-like domain COG2 PF06148.6 ETO29958.1 - 0.04 13.7 13.8 0.1 12.4 2.7 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Prominin PF05478.6 ETO29958.1 - 0.061 10.8 12.5 0.081 10.4 8.7 1.2 1 0 0 1 1 1 0 Prominin Asp_Arg_Hydrox PF05118.10 ETO29958.1 - 0.064 13.0 2.3 0.096 12.5 1.5 1.4 1 1 0 1 1 1 0 Aspartyl/Asparaginyl beta-hydroxylase DUF1647 PF07801.6 ETO29958.1 - 0.12 11.8 1.3 0.21 11.1 0.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1647) GAS PF13851.1 ETO29958.1 - 0.14 11.3 22.9 0.055 12.6 4.7 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.4 ETO29958.1 - 0.15 12.2 14.8 0.22 11.6 0.3 3.3 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FH2 PF02181.18 ETO29958.1 - 0.19 10.5 14.8 0.52 9.1 5.4 2.2 1 1 1 2 2 2 0 Formin Homology 2 Domain Ribosomal_S3Ae PF01015.13 ETO29958.1 - 0.2 10.9 6.2 0.81 8.9 1.5 2.5 2 1 0 2 2 2 0 Ribosomal S3Ae family Hemerythrin PF01814.18 ETO29958.1 - 0.22 11.6 2.9 4.5 7.4 2.0 2.6 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain DUF773 PF05600.7 ETO29958.1 - 0.25 10.0 19.5 0.024 13.4 4.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF773) Amidase PF01425.16 ETO29958.1 - 0.29 9.9 2.0 0.33 9.7 1.4 1.1 1 0 0 1 1 1 0 Amidase Complex1_LYR_2 PF13233.1 ETO29958.1 - 0.31 11.5 8.7 0.04 14.4 0.5 2.5 1 1 1 2 2 2 0 Complex1_LYR-like Baculo_PEP_C PF04513.7 ETO29958.1 - 0.38 10.5 14.5 0.73 9.6 3.1 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_GP20 PF06810.6 ETO29958.1 - 0.39 10.1 22.9 1.2 8.5 0.1 3.1 1 1 2 3 3 3 0 Phage minor structural protein GP20 DUF904 PF06005.7 ETO29958.1 - 0.4 10.9 22.2 1.4 9.2 4.8 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF904) DUF1664 PF07889.7 ETO29958.1 - 0.43 10.3 9.9 0.23 11.2 1.9 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF45 PF01863.12 ETO29958.1 - 0.44 10.3 7.2 0.46 10.2 4.3 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF45 MbeD_MobD PF04899.7 ETO29958.1 - 0.53 10.2 15.4 5 7.0 0.9 3.4 2 1 1 3 3 3 0 MbeD/MobD like MCPsignal PF00015.16 ETO29958.1 - 0.61 9.5 7.8 0.05 13.1 2.1 1.6 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain NPV_P10 PF05531.7 ETO29958.1 - 0.8 9.9 15.6 7.7 6.8 0.8 3.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein PCRF PF03462.13 ETO29958.1 - 0.83 9.3 9.2 2.2 7.9 2.0 2.7 2 1 1 3 3 3 0 PCRF domain Reo_sigmaC PF04582.7 ETO29958.1 - 0.96 8.5 6.7 0.64 9.1 1.2 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein TMF_TATA_bd PF12325.3 ETO29958.1 - 1.2 8.8 20.5 1.2 8.9 0.8 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding HSCB_C PF07743.8 ETO29958.1 - 1.3 9.5 14.6 2.6 8.5 2.9 3.0 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain DUF4618 PF15397.1 ETO29958.1 - 1.4 8.1 23.1 2.7 7.2 16.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) Prefoldin PF02996.12 ETO29958.1 - 1.6 8.3 18.7 0.16 11.6 2.8 3.8 3 2 0 3 3 3 0 Prefoldin subunit DUF4225 PF13988.1 ETO29958.1 - 1.9 7.9 7.8 0.67 9.4 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) Atg14 PF10186.4 ETO29958.1 - 2 7.2 19.7 4.5 6.1 13.6 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TIP120 PF08623.5 ETO29958.1 - 2.2 7.8 12.8 0.14 11.7 2.6 2.1 1 1 0 2 2 2 0 TATA-binding protein interacting (TIP20) CbiG_C PF01890.11 ETO29958.1 - 2.3 8.5 5.3 36 4.6 3.7 2.4 1 1 0 1 1 1 0 Cobalamin synthesis G C-terminus CCDC-167 PF15188.1 ETO29958.1 - 3.2 7.7 10.6 0.46 10.4 1.9 3.0 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 FlxA PF14282.1 ETO29958.1 - 3.2 7.7 28.2 9.4 6.2 5.2 3.5 2 1 1 3 3 3 0 FlxA-like protein 4HB_MCP_1 PF12729.2 ETO29958.1 - 3.8 6.8 15.2 1.8 7.8 7.8 2.0 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction Occludin_ELL PF07303.8 ETO29958.1 - 4.1 8.2 16.5 23 5.7 4.9 3.3 1 1 2 3 3 3 0 Occludin homology domain Seryl_tRNA_N PF02403.17 ETO29958.1 - 4.8 7.2 18.2 14 5.7 3.7 3.3 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF2324 PF10086.4 ETO29959.1 - 0.00063 19.0 0.1 0.0021 17.3 0.0 1.9 1 1 1 2 2 2 1 Putative membrane peptidase family (DUF2324) Met_synt_B12 PF02965.12 ETO29960.1 - 8.2e-68 227.7 0.0 1.7e-67 226.7 0.0 1.5 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain Pterin_bind PF00809.17 ETO29960.1 - 9.3e-42 142.7 0.3 2.2e-41 141.5 0.2 1.7 1 0 0 1 1 1 1 Pterin binding enzyme B12-binding_2 PF02607.12 ETO29960.1 - 6e-20 71.0 0.1 2e-19 69.3 0.0 2.0 2 0 0 2 2 2 1 B12 binding domain S-methyl_trans PF02574.11 ETO29960.1 - 1.2e-19 70.7 0.0 3e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 Homocysteine S-methyltransferase B12-binding PF02310.14 ETO29960.1 - 8.9e-15 54.6 0.0 4.2e-14 52.4 0.0 2.1 2 0 0 2 2 2 1 B12 binding domain KRTDAP PF15200.1 ETO29960.1 - 0.093 12.5 0.1 0.34 10.6 0.1 2.0 1 0 0 1 1 1 0 Keratinocyte differentiation-associated FLO_LFY PF01698.11 ETO29961.1 - 0.004 16.0 1.9 0.0052 15.6 1.3 1.1 1 0 0 1 1 1 1 Floricaula / Leafy protein Cupin_4 PF08007.7 ETO29962.1 - 7.1e-29 101.0 0.0 1.1e-28 100.3 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.1 ETO29962.1 - 0.072 12.5 1.1 0.21 11.0 0.8 2.0 1 1 0 1 1 1 0 Cupin-like domain Daxx PF03344.10 ETO29963.1 - 0.074 11.5 5.4 0.068 11.6 3.8 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 ETO29963.1 - 0.35 8.7 7.9 0.45 8.3 5.5 1.2 1 0 0 1 1 1 0 Nop14-like family eIF-3c_N PF05470.7 ETO29963.1 - 1.1 7.3 5.7 1.6 6.7 3.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SDA1 PF05285.7 ETO29963.1 - 1.2 8.3 10.3 1.5 7.9 7.2 1.2 1 0 0 1 1 1 0 SDA1 WD40 PF00400.27 ETO29965.1 - 0.00037 20.2 0.0 0.00063 19.5 0.0 1.4 1 0 0 1 1 1 1 WD domain, G-beta repeat WD40 PF00400.27 ETO29966.1 - 1.2e-38 129.5 3.7 1.9e-12 46.5 0.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat PD40 PF07676.7 ETO29966.1 - 0.00025 20.6 0.0 1.2 8.8 0.0 3.5 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO29966.1 - 0.071 11.3 1.0 0.3 9.3 0.2 2.0 1 1 2 3 3 3 0 Cytochrome D1 heme domain CTP_transf_2 PF01467.21 ETO29968.1 - 8.4e-05 22.6 3.0 0.00011 22.3 0.1 2.6 3 1 0 3 3 3 1 Cytidylyltransferase SH3_8 PF13457.1 ETO29969.1 - 0.051 13.7 6.6 0.049 13.7 2.1 2.2 1 1 1 2 2 2 0 SH3-like domain ASD2 PF08687.6 ETO29969.1 - 0.16 11.2 2.3 0.2 10.9 1.6 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 DUF2702 PF10863.3 ETO29969.1 - 0.19 11.4 7.6 0.16 11.6 1.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2702) Mlf1IP PF10248.4 ETO29969.1 - 0.35 10.4 4.5 0.62 9.6 3.1 1.5 1 1 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Nudix_N_2 PF14803.1 ETO29970.1 - 0.045 13.4 0.3 3.1 7.5 0.1 2.6 2 0 0 2 2 2 0 Nudix N-terminal DUF4366 PF14283.1 ETO29972.1 - 0.0064 15.9 0.9 0.89 8.9 0.0 3.0 2 1 1 3 3 3 2 Domain of unknown function (DUF4366) DUF2777 PF10949.3 ETO29972.1 - 0.049 13.3 0.2 0.079 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2777) WD40 PF00400.27 ETO29973.1 - 1.4e-72 237.1 17.6 2.2e-13 49.5 0.1 7.0 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO29973.1 - 3.1e-14 53.1 0.2 1.2e-05 25.1 0.0 3.7 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO29973.1 - 1.2e-09 37.6 7.2 0.27 10.9 0.0 6.4 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO29973.1 - 1.2e-06 27.0 0.1 0.0027 16.0 0.0 2.4 2 1 0 2 2 2 2 Cytochrome D1 heme domain DUF1258 PF06869.7 ETO29973.1 - 3.2e-06 26.4 1.5 0.05 12.6 0.0 3.2 2 1 1 3 3 3 2 Protein of unknown function (DUF1258) Nup160 PF11715.3 ETO29973.1 - 6.1e-05 21.3 6.2 0.39 8.8 0.0 4.3 1 1 3 4 4 4 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO29973.1 - 0.00027 20.5 0.4 0.001 18.5 0.3 1.9 1 1 0 1 1 1 1 PQQ-like domain Gmad1 PF10647.4 ETO29973.1 - 0.0011 18.4 0.1 1.2 8.4 0.1 3.5 2 1 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain Nucleoporin_N PF08801.6 ETO29973.1 - 0.0014 17.4 7.7 0.19 10.4 0.1 3.7 1 1 3 4 4 4 2 Nup133 N terminal like DUF4221 PF13970.1 ETO29973.1 - 0.017 14.4 0.1 3.6 6.8 0.0 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4221) TFIIIC_delta PF12657.2 ETO29973.1 - 0.036 13.7 2.9 0.33 10.6 0.3 2.3 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term Resistin PF06954.6 ETO29973.1 - 0.41 10.9 3.2 31 4.9 0.0 4.1 2 2 2 5 5 5 0 Resistin Proteasome_A_N PF10584.4 ETO29973.1 - 0.58 9.5 6.2 65 2.9 0.1 4.6 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Metallophos PF00149.23 ETO29974.1 - 0.0029 17.0 0.1 0.0042 16.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PI3_PI4_kinase PF00454.22 ETO29976.1 - 4.2e-28 98.4 7.0 6.5e-17 61.7 0.1 4.0 4 1 1 5 5 5 2 Phosphatidylinositol 3- and 4-kinase Ras PF00071.17 ETO29978.1 - 2.7e-44 150.4 7.0 1.3e-31 109.1 0.2 2.1 1 1 1 2 2 2 2 Ras family Miro PF08477.8 ETO29978.1 - 9.7e-11 42.2 0.7 1.1e-08 35.6 0.2 2.5 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO29978.1 - 8.3e-07 28.4 3.5 0.0058 15.8 0.3 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO29978.1 - 6.9e-05 22.3 1.0 0.043 13.2 0.1 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 ETO29978.1 - 0.00075 18.6 0.8 0.0011 18.1 0.6 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region EcsC PF12787.2 ETO29979.1 - 0.0023 17.3 7.5 0.24 10.7 0.6 2.3 2 0 0 2 2 2 2 EcsC protein family Endonuc-BsobI PF09194.5 ETO29979.1 - 0.011 14.7 0.5 2.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Restriction endonuclease BsobI TEX33 PF15400.1 ETO29979.1 - 0.049 14.0 1.0 1.6 9.1 0.1 2.5 2 0 0 2 2 2 0 Testis-expressed sequence 33 protein family Peptidase_U35_2 PF14550.1 ETO29979.1 - 0.05 13.2 1.4 6 6.4 0.2 2.7 2 0 0 2 2 2 0 Putative phage protease XkdF PriCT_1 PF08708.6 ETO29979.1 - 0.06 13.1 0.3 12 5.7 0.0 2.5 2 0 0 2 2 2 0 Primase C terminal 1 (PriCT-1) CYTL1 PF15153.1 ETO29979.1 - 0.36 10.5 6.2 1.8 8.2 0.4 2.9 3 0 0 3 3 3 0 Cytokine-like protein 1 DUF1947 PF09183.5 ETO29979.1 - 1.7 8.4 11.7 0.68 9.7 0.2 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1947) Pex24p PF06398.6 ETO29979.1 - 5 5.8 10.2 3.3 6.4 0.7 2.3 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin DUF775 PF05603.7 ETO29980.1 - 0.0034 16.9 2.9 0.0034 16.9 2.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF775) PH PF00169.24 ETO29980.1 - 0.044 13.9 0.4 0.044 13.9 0.3 2.5 2 0 0 2 2 2 0 PH domain ACT_6 PF13740.1 ETO29980.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 ACT domain CDK2AP PF09806.4 ETO29980.1 - 1.7 8.8 12.7 0.58 10.3 6.6 1.8 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein SCF PF02404.10 ETO29981.1 - 0.044 12.9 0.2 0.067 12.3 0.2 1.2 1 0 0 1 1 1 0 Stem cell factor Pkinase PF00069.20 ETO29982.1 - 8.9e-21 74.1 0.3 2.8e-20 72.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO29982.1 - 1.9e-05 23.8 0.0 3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 ETO29983.1 - 7.4e-35 120.3 1.3 1.5e-34 119.3 0.9 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO29983.1 - 9.1e-20 70.8 1.0 1.6e-19 69.9 0.3 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Nudix_N_2 PF14803.1 ETO29983.1 - 0.13 11.9 2.4 0.14 11.9 0.1 2.2 2 0 0 2 2 2 0 Nudix N-terminal TFIIS_C PF01096.13 ETO29983.1 - 0.2 11.3 0.2 0.2 11.3 0.1 2.0 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) PH PF00169.24 ETO29983.1 - 0.39 10.9 2.6 1.2 9.4 0.5 2.6 2 1 0 2 2 2 0 PH domain Ceramidase PF05875.7 ETO29984.1 - 1.2e-41 142.5 23.4 1.4e-41 142.3 14.2 2.3 1 1 1 2 2 2 1 Ceramidase PTPLA PF04387.9 ETO29984.1 - 0.0048 16.3 0.5 0.0048 16.3 0.4 3.3 3 1 1 4 4 4 1 Protein tyrosine phosphatase-like protein, PTPLA DUF912 PF06024.7 ETO29984.1 - 0.081 12.9 0.2 0.31 11.0 0.0 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Viral_Beta_CD PF04530.7 ETO29984.1 - 0.11 12.6 1.5 0.81 9.8 0.0 2.4 2 0 0 2 2 2 0 Viral Beta C/D like family RasGEF PF00617.14 ETO29985.1 - 1.2e-20 73.9 0.2 3.2e-20 72.6 0.1 1.6 1 0 0 1 1 1 1 RasGEF domain Radical_SAM PF04055.16 ETO29987.1 - 2.5e-16 60.3 0.2 7.5e-16 58.7 0.2 1.8 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 ETO29987.1 - 1.1e-07 31.7 0.1 7.6e-06 25.8 0.0 2.7 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 ETO29987.1 - 0.12 12.4 0.1 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GTP_EFTU_D4 PF14578.1 ETO29988.1 - 2.3e-06 27.1 0.4 5.3e-06 25.9 0.3 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.20 ETO29988.1 - 0.0011 19.0 0.2 0.0027 17.8 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU PF00009.22 ETO29989.1 - 5.2e-09 35.7 0.0 1.4e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 ETO29989.1 - 0.00032 21.1 0.0 0.0012 19.3 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 ETO29989.1 - 0.00036 20.4 0.0 0.0012 18.7 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 ETO29989.1 - 0.008 15.4 0.0 1.5 7.9 0.0 2.9 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 ETO29989.1 - 0.14 12.1 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.18 ETO29989.1 - 3 7.6 8.8 2 8.2 0.8 3.0 3 1 0 3 3 3 0 Dynamin family Piwi PF02171.12 ETO29993.1 - 2.3e-12 46.5 0.0 3e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Piwi domain PUF PF00806.14 ETO29994.1 - 1.8e-51 168.7 4.2 1.4e-08 33.7 0.0 7.6 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat Spore_coat_CotO PF14153.1 ETO29996.1 - 0.00073 19.0 8.0 0.001 18.5 5.6 1.3 1 0 0 1 1 1 1 Spore coat protein CotO PH PF00169.24 ETO29996.1 - 0.023 14.8 5.3 0.085 13.0 0.0 2.5 2 0 0 2 2 2 0 PH domain Exostosin PF03016.10 ETO29996.1 - 0.032 13.2 1.1 0.049 12.6 0.7 1.3 1 0 0 1 1 1 0 Exostosin family DDRGK PF09756.4 ETO29996.1 - 0.41 10.0 18.1 0.71 9.2 12.6 1.3 1 0 0 1 1 1 0 DDRGK domain DUF1510 PF07423.6 ETO29996.1 - 5.9 6.1 21.5 9.7 5.4 14.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DDHD PF02862.12 ETO29996.1 - 6.3 6.5 12.0 14 5.3 8.3 1.6 1 0 0 1 1 1 0 DDHD domain Cellulose_synt PF03552.9 ETO29996.1 - 7.9 4.6 6.1 11 4.1 4.2 1.2 1 0 0 1 1 1 0 Cellulose synthase DUF4407 PF14362.1 ETO29996.1 - 8.5 5.2 9.1 13 4.6 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Vps5 PF09325.5 ETO29997.1 - 0.0071 15.6 4.1 0.0096 15.1 2.9 1.2 1 0 0 1 1 1 1 Vps5 C terminal like DUF1843 PF08898.5 ETO29997.1 - 0.024 14.6 1.0 0.053 13.5 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) BBP1_C PF15272.1 ETO29997.1 - 0.024 14.1 9.8 0.027 14.0 6.8 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal HRDC PF00570.18 ETO29997.1 - 0.027 14.1 0.2 0.044 13.4 0.1 1.4 1 0 0 1 1 1 0 HRDC domain CENP-F_leu_zip PF10473.4 ETO29997.1 - 0.053 13.3 8.1 0.067 13.0 5.6 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 ETO29997.1 - 0.062 12.8 7.8 0.066 12.7 5.4 1.1 1 0 0 1 1 1 0 IncA protein Baculo_PEP_C PF04513.7 ETO29997.1 - 0.086 12.6 10.5 0.11 12.3 7.2 1.0 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Med4 PF10018.4 ETO29997.1 - 0.15 11.4 5.9 0.23 10.8 4.1 1.4 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF1664 PF07889.7 ETO29997.1 - 0.27 11.0 2.8 0.38 10.5 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) APG6 PF04111.7 ETO29997.1 - 0.29 10.1 11.2 0.3 10.0 7.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DASH_Spc19 PF08287.6 ETO29997.1 - 0.39 10.3 14.2 0.87 9.1 8.1 2.0 1 1 1 2 2 2 0 Spc19 Velvet PF11754.3 ETO29997.1 - 0.43 10.1 4.1 0.6 9.6 2.7 1.3 1 1 0 1 1 1 0 Velvet factor DUF2968 PF11180.3 ETO29997.1 - 0.43 9.9 6.0 0.52 9.6 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Fmp27_WPPW PF10359.4 ETO29997.1 - 0.48 8.7 11.8 0.55 8.5 8.2 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DivIC PF04977.10 ETO29997.1 - 0.56 9.7 7.1 0.31 10.5 2.4 2.2 1 1 1 2 2 2 0 Septum formation initiator TMF_TATA_bd PF12325.3 ETO29997.1 - 0.72 9.6 9.2 0.33 10.6 4.6 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF3847 PF12958.2 ETO29997.1 - 0.78 9.5 7.7 0.085 12.6 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) DASH_Dad2 PF08654.5 ETO29997.1 - 0.78 9.7 9.1 0.26 11.3 4.5 1.5 2 0 0 2 2 1 0 DASH complex subunit Dad2 DUF1320 PF07030.7 ETO29997.1 - 1.3 8.7 3.8 15 5.3 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1320) DUF334 PF03904.8 ETO29997.1 - 5.8 6.1 17.0 0.027 13.7 4.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF334) Striatin PF08232.7 ETO29997.1 - 5.8 7.2 11.4 13 6.0 7.9 1.6 1 1 0 1 1 1 0 Striatin family Tim17 PF02466.14 ETO29998.1 - 3.1e-07 30.4 0.1 5.2e-07 29.7 0.0 1.3 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Prenyltrans_1 PF13243.1 ETO29998.1 - 7.1e-05 22.7 0.0 0.00011 22.1 0.0 1.2 1 0 0 1 1 1 1 Prenyltransferase-like LRR_6 PF13516.1 ETO29999.1 - 2.8e-06 26.8 2.1 0.023 14.7 0.0 4.6 4 0 0 4 4 4 1 Leucine Rich repeat LRR_4 PF12799.2 ETO29999.1 - 8e-05 22.1 0.4 0.011 15.3 0.0 3.3 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETO29999.1 - 0.0035 17.1 1.6 15 6.0 0.1 4.3 4 1 0 4 4 4 1 Leucine Rich Repeat LRR_8 PF13855.1 ETO29999.1 - 0.0057 16.3 2.2 0.14 11.9 0.0 3.4 4 0 0 4 4 4 1 Leucine rich repeat LRR_2 PF07723.8 ETO29999.1 - 0.11 13.0 0.7 0.51 10.9 0.0 2.6 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_7 PF13504.1 ETO29999.1 - 0.13 12.5 0.7 42 4.9 0.0 3.4 4 0 0 4 4 4 0 Leucine rich repeat Piwi PF02171.12 ETO30000.1 - 0.002 17.1 0.0 0.0025 16.8 0.0 1.1 1 0 0 1 1 1 1 Piwi domain Piwi PF02171.12 ETO30001.1 - 0.031 13.2 0.0 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 Piwi domain RGS PF00615.14 ETO30002.1 - 2.5e-06 27.5 0.2 8.1e-06 25.9 0.1 1.9 1 1 0 1 1 1 1 Regulator of G protein signaling domain AMP-binding PF00501.23 ETO30003.1 - 2.7e-33 114.9 0.1 1e-32 113.0 0.1 1.7 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETO30003.1 - 0.088 13.7 0.0 0.16 12.9 0.0 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain DUF4205 PF13898.1 ETO30004.1 - 9e-53 179.1 0.0 1.5e-49 168.6 0.0 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF4205) zf-RanBP PF00641.13 ETO30004.1 - 0.00047 19.2 4.3 0.00092 18.2 3.0 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others tRNA-synt_1 PF00133.17 ETO30005.1 - 2.3e-09 35.8 4.7 8.3e-07 27.3 0.0 2.8 2 1 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 ETO30005.1 - 3.3e-06 26.0 0.0 4.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (M) Peptidase_C37 PF05416.7 ETO30005.1 - 0.0016 16.8 4.0 0.0021 16.4 2.7 1.0 1 0 0 1 1 1 1 Southampton virus-type processing peptidase Myc_N PF01056.13 ETO30005.1 - 0.015 14.5 2.2 0.019 14.1 1.6 1.1 1 0 0 1 1 1 0 Myc amino-terminal region RNase_H2-Ydr279 PF09468.5 ETO30005.1 - 0.021 14.0 2.8 0.026 13.7 1.9 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Vfa1 PF08432.5 ETO30005.1 - 0.03 14.3 5.5 0.041 13.9 3.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FAM176 PF14851.1 ETO30005.1 - 0.039 13.6 0.3 0.052 13.2 0.2 1.2 1 0 0 1 1 1 0 FAM176 family Nucleoplasmin PF03066.10 ETO30005.1 - 0.14 11.6 9.2 0.19 11.2 6.4 1.1 1 0 0 1 1 1 0 Nucleoplasmin RNA_pol_Rpc4 PF05132.9 ETO30005.1 - 0.16 11.9 8.9 0.22 11.5 6.2 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF2201_N PF13203.1 ETO30005.1 - 0.18 10.9 1.3 0.2 10.8 0.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.9 ETO30005.1 - 0.18 9.8 7.3 0.21 9.5 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.1 ETO30005.1 - 0.27 11.5 9.5 0.4 11.0 6.6 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Paf1 PF03985.8 ETO30005.1 - 0.39 9.4 12.9 0.51 9.0 9.0 1.1 1 0 0 1 1 1 0 Paf1 Pox_Ag35 PF03286.9 ETO30005.1 - 0.41 10.1 6.9 0.5 9.8 4.8 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CobT PF06213.7 ETO30005.1 - 0.52 9.4 8.9 0.66 9.0 6.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RR_TM4-6 PF06459.7 ETO30005.1 - 0.57 10.0 9.4 0.7 9.7 6.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sec62 PF03839.11 ETO30005.1 - 0.64 9.3 4.9 0.86 8.9 3.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Daxx PF03344.10 ETO30005.1 - 0.79 8.1 12.8 0.93 7.8 8.9 1.0 1 0 0 1 1 1 0 Daxx Family Herpes_DNAp_acc PF04929.7 ETO30005.1 - 0.82 8.5 2.7 1 8.2 1.9 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor BEX PF04538.7 ETO30005.1 - 1.6 9.0 18.3 0.28 11.4 10.3 1.5 2 0 0 2 2 1 0 Brain expressed X-linked like family Nop14 PF04147.7 ETO30005.1 - 1.6 6.5 13.6 2.1 6.1 9.4 1.0 1 0 0 1 1 1 0 Nop14-like family RNA_polI_A34 PF08208.6 ETO30005.1 - 1.6 8.3 15.6 2.2 7.9 10.8 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 HSP90 PF00183.13 ETO30005.1 - 1.6 7.0 13.8 2.2 6.5 9.6 1.1 1 0 0 1 1 1 0 Hsp90 protein Sporozoite_P67 PF05642.6 ETO30005.1 - 1.8 6.2 7.9 2.3 5.9 5.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen YqfQ PF14181.1 ETO30005.1 - 2.3 8.2 10.3 3.1 7.8 7.2 1.1 1 0 0 1 1 1 0 YqfQ-like protein DUF1510 PF07423.6 ETO30005.1 - 2.5 7.4 13.8 3.5 6.9 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF809 PF05663.6 ETO30005.1 - 2.8 7.8 7.8 5.5 6.9 5.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF809) TFIIF_alpha PF05793.7 ETO30005.1 - 2.9 6.1 18.5 3.7 5.8 12.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3381 PF11861.3 ETO30005.1 - 5 6.6 16.7 7.1 6.1 11.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) CENP-B_dimeris PF09026.5 ETO30005.1 - 8.1 6.7 11.0 14 5.9 7.6 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-RING_2 PF13639.1 ETO30007.1 - 0.11 12.3 5.7 0.16 11.8 0.1 2.6 2 1 1 3 3 3 0 Ring finger domain zf-RING_5 PF14634.1 ETO30007.1 - 0.22 11.3 7.5 1.1 9.0 4.5 2.5 2 1 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 ETO30007.1 - 1.7 8.3 6.5 14 5.4 3.9 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO30007.1 - 1.9 8.5 8.0 0.9 9.6 0.2 2.9 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 ETO30007.1 - 5.3 6.9 8.7 21 5.1 0.2 2.9 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING LRR_4 PF12799.2 ETO30008.1 - 0.031 13.8 0.1 0.21 11.2 0.2 2.1 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 ETO30008.1 - 0.041 13.9 0.1 30 5.1 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich repeat PABP PF00658.13 ETO30009.1 - 3.2e-09 36.3 0.0 6e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain DUF2614 PF11023.3 ETO30010.1 - 0.33 10.7 6.7 1.3 8.8 3.5 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2614) Metallophos PF00149.23 ETO30011.1 - 1.6e-37 128.8 0.1 4.9e-35 120.7 0.0 2.9 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Aph-1 PF06105.7 ETO30012.1 - 2.9e-30 105.3 21.9 2.9e-30 105.3 15.2 1.7 2 0 0 2 2 2 1 Aph-1 protein Rep_fac-A_3 PF08661.6 ETO30013.1 - 0.1 12.4 0.1 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Replication factor A protein 3 TK PF00265.13 ETO30015.1 - 0.058 12.9 0.6 0.069 12.7 0.4 1.1 1 0 0 1 1 1 0 Thymidine kinase ATP-synt_8 PF00895.15 ETO30016.1 - 0.16 12.2 1.3 0.44 10.7 0.9 1.7 1 0 0 1 1 1 0 ATP synthase protein 8 Pkinase PF00069.20 ETO30017.1 - 2.3e-09 36.8 0.2 6.6e-09 35.2 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO30017.1 - 0.00061 18.9 0.3 0.0022 17.1 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Rota_NSP3 PF01665.11 ETO30017.1 - 0.037 12.9 0.4 0.074 11.9 0.3 1.5 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 NAD_binding_4 PF07993.7 ETO30018.1 - 2.4e-52 177.3 0.0 4.2e-52 176.5 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.14 ETO30018.1 - 6.6e-07 29.5 0.6 1.9e-06 28.0 0.4 1.7 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 ETO30018.1 - 2.7e-05 23.0 2.5 0.0061 15.2 1.1 3.0 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 ETO30018.1 - 0.00021 20.7 0.1 0.002 17.5 0.1 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 ETO30018.1 - 0.076 11.9 1.5 1.8 7.4 0.2 2.8 1 1 0 2 2 2 0 Polysaccharide biosynthesis protein RRM_1 PF00076.17 ETO30019.1 - 1.2e-06 27.9 0.0 2.6e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO30019.1 - 1.5e-05 24.8 0.2 3.2e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ETF_QO PF05187.8 ETO30019.1 - 0.18 11.8 0.8 0.28 11.1 0.3 1.5 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase Papo_T_antigen PF02380.10 ETO30019.1 - 0.42 10.5 6.7 0.9 9.5 4.7 1.6 1 1 0 1 1 1 0 T-antigen specific domain Thiolase_C PF02803.13 ETO30020.1 - 0.045 13.1 0.5 0.1 12.0 0.1 1.7 2 0 0 2 2 2 0 Thiolase, C-terminal domain 7tm_3 PF00003.17 ETO30022.1 - 8.6e-14 51.4 29.7 3.2e-10 39.7 9.7 2.5 1 1 1 2 2 2 2 7 transmembrane sweet-taste receptor of 3 GCPR Ribonuclease_3 PF00636.21 ETO30023.1 - 6.8e-13 49.0 0.1 2.2e-12 47.4 0.1 1.9 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 ETO30023.1 - 2e-11 43.9 0.1 1.2e-09 38.2 0.1 2.3 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 ETO30024.1 - 0.022 15.1 1.2 0.15 12.5 0.0 2.8 2 1 0 2 2 2 0 Ribonuclease III domain DUF2389 PF09493.5 ETO30024.1 - 0.15 12.3 2.8 0.63 10.3 0.1 2.7 2 1 0 2 2 2 0 Tryptophan-rich protein (DUF2389) Inositol_P PF00459.20 ETO30025.1 - 8.1e-65 218.8 0.0 1.1e-64 218.3 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.15 ETO30025.1 - 0.047 12.5 0.0 0.07 11.9 0.0 1.2 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase YedD PF13987.1 ETO30025.1 - 0.082 12.4 0.0 0.26 10.8 0.0 1.8 2 0 0 2 2 2 0 YedD-like protein tRNA_synt_1c_R2 PF04557.10 ETO30026.1 - 0.044 14.4 11.7 0.044 14.4 8.1 2.2 1 1 1 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 DUF2201_N PF13203.1 ETO30026.1 - 0.066 12.3 10.0 0.068 12.3 6.9 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF1510 PF07423.6 ETO30026.1 - 0.079 12.3 26.0 0.091 12.1 18.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) hDGE_amylase PF14701.1 ETO30026.1 - 0.16 10.8 9.1 0.16 10.8 6.3 1.0 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Zip PF02535.17 ETO30026.1 - 0.34 9.8 7.8 0.44 9.5 5.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2413 PF10310.4 ETO30026.1 - 6.4 5.4 22.6 7.2 5.3 15.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Ycf1 PF05758.7 ETO30026.1 - 7.3 4.1 21.2 7.8 4.0 14.7 1.1 1 0 0 1 1 1 0 Ycf1 DUF262 PF03235.9 ETO30026.1 - 7.5 6.4 11.3 9.5 6.1 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 Glyco_hydro_3_C PF01915.17 ETO30027.1 - 0.0063 16.0 0.1 0.0084 15.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain PI3_PI4_kinase PF00454.22 ETO30028.1 - 2.1e-54 184.4 0.4 3.3e-54 183.8 0.3 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 ETO30028.1 - 3.5e-15 55.1 0.2 7.2e-15 54.1 0.1 1.6 1 0 0 1 1 1 1 FATC domain SNase PF00565.12 ETO30030.1 - 1.7e-15 57.2 2.4 8e-09 35.7 0.0 3.5 2 2 1 3 3 3 2 Staphylococcal nuclease homologue TUDOR PF00567.19 ETO30030.1 - 0.0018 18.0 0.2 0.0062 16.3 0.0 2.0 2 0 0 2 2 2 1 Tudor domain Myotub-related PF06602.9 ETO30031.1 - 0.1 11.3 0.4 0.13 11.0 0.3 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Ank_2 PF12796.2 ETO30032.1 - 0.00014 22.1 0.0 0.00037 20.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO30032.1 - 0.012 15.7 0.0 5.9 7.4 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.1 ETO30032.1 - 0.022 15.0 4.2 0.045 14.0 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Selenoprotein_S PF06936.6 ETO30033.1 - 6.1 6.3 7.0 3.2 7.2 3.5 1.5 2 0 0 2 2 2 0 Selenoprotein S (SelS) DUF106 PF01956.11 ETO30037.1 - 6e-19 68.2 0.6 7e-19 67.9 0.4 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 COX14 PF14880.1 ETO30037.1 - 3.7 7.2 5.5 0.33 10.6 0.4 1.7 2 0 0 2 2 2 0 Cytochrome oxidase c assembly RhoGAP PF00620.22 ETO30039.1 - 0.061 12.9 0.1 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 RhoGAP domain C2 PF00168.25 ETO30040.1 - 6.4e-24 83.6 0.3 9.7e-24 83.0 0.2 1.3 1 0 0 1 1 1 1 C2 domain Sec62 PF03839.11 ETO30041.1 - 0.018 14.4 0.6 0.029 13.7 0.4 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Otopetrin PF03189.8 ETO30041.1 - 0.021 13.8 0.5 0.025 13.6 0.3 1.1 1 0 0 1 1 1 0 Otopetrin Ycf1 PF05758.7 ETO30041.1 - 0.031 12.0 3.1 0.032 11.9 2.2 1.1 1 0 0 1 1 1 0 Ycf1 DUF2457 PF10446.4 ETO30041.1 - 0.22 10.2 8.7 0.29 9.8 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) UPF0172 PF03665.8 ETO30041.1 - 0.65 9.4 3.5 0.95 8.9 2.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) Trypan_PARP PF05887.6 ETO30041.1 - 3.8 7.3 9.2 5.7 6.7 6.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Cytomega_UL84 PF06284.6 ETO30041.1 - 4.5 5.5 5.8 5.4 5.3 4.0 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DivIC PF04977.10 ETO30044.1 - 3.5 7.1 11.7 6.3 6.3 0.5 3.7 3 0 0 3 3 3 0 Septum formation initiator DNase_II PF03265.10 ETO30045.1 - 2.4e-52 177.9 13.6 3.8e-51 174.0 9.4 2.0 1 1 0 1 1 1 1 Deoxyribonuclease II zf-TRAF PF02176.13 ETO30046.1 - 1.7e-06 28.2 3.1 1.7e-06 28.2 2.2 3.7 2 1 1 3 3 3 2 TRAF-type zinc finger Sina PF03145.11 ETO30046.1 - 0.00025 20.7 3.9 0.00025 20.7 2.7 2.1 2 0 0 2 2 2 1 Seven in absentia protein family GAGA PF09237.6 ETO30046.1 - 0.037 13.6 0.9 0.22 11.1 0.2 2.3 2 0 0 2 2 2 0 GAGA factor Tubulin_C PF03953.12 ETO30048.1 - 1.3e-21 76.9 0.0 1.9e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain zf-C3HC4_3 PF13920.1 ETO30050.1 - 0.00049 19.7 9.4 0.0013 18.3 6.4 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1777 PF08648.7 ETO30050.1 - 0.048 13.3 8.6 0.073 12.8 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) ASFV_J13L PF05568.6 ETO30050.1 - 0.13 11.7 0.4 0.19 11.2 0.3 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein Vpu PF00558.14 ETO30050.1 - 0.31 10.6 3.3 1 8.9 2.3 1.8 1 0 0 1 1 1 0 Vpu protein DUF2681 PF10883.3 ETO30050.1 - 3.6 7.8 6.9 0.38 10.9 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) zf-RING_5 PF14634.1 ETO30050.1 - 6.6 6.5 10.3 0.85 9.3 3.8 2.0 2 1 0 2 2 2 0 zinc-RING finger domain DUF3139 PF11337.3 ETO30050.1 - 8.4 6.7 13.7 0.17 12.2 1.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3139) Daxx PF03344.10 ETO30051.1 - 1.1 7.7 48.9 1.5 7.1 33.9 1.2 1 0 0 1 1 1 0 Daxx Family 60KD_IMP PF02096.15 ETO30053.1 - 3e-09 36.8 2.7 9e-09 35.2 1.9 1.7 1 1 0 1 1 1 1 60Kd inner membrane protein PH_2 PF08458.5 ETO30054.1 - 0.049 13.5 1.0 0.16 11.9 0.0 2.2 2 1 0 2 2 2 0 Plant pleckstrin homology-like region PH PF00169.24 ETO30054.1 - 0.12 12.6 2.9 0.12 12.5 0.4 2.1 2 0 0 2 2 2 0 PH domain zf-C3HC4_2 PF13923.1 ETO30055.1 - 0.027 14.4 1.0 0.21 11.6 0.2 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RNB PF00773.14 ETO30055.1 - 0.13 11.4 0.0 0.16 11.2 0.0 1.3 1 1 0 1 1 1 0 RNB domain DUF1724 PF08350.5 ETO30056.1 - 0.075 12.5 0.1 0.35 10.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1724) SBDS PF01172.13 ETO30056.1 - 0.075 12.8 0.6 0.24 11.1 0.1 1.9 2 0 0 2 2 2 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein Tfb4 PF03850.9 ETO30056.1 - 0.091 12.0 0.6 0.11 11.7 0.4 1.1 1 0 0 1 1 1 0 Transcription factor Tfb4 ATAD4 PF15321.1 ETO30056.1 - 0.87 10.6 4.5 1.8 9.6 3.2 1.9 1 1 0 1 1 1 0 ATPase family AAA domain containing 4 YlbE PF14003.1 ETO30057.1 - 0.11 12.5 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 YlbE-like protein UBA_4 PF14555.1 ETO30058.1 - 0.00039 19.8 0.1 0.002 17.5 0.1 2.1 2 0 0 2 2 2 1 UBA-like domain FtsK_SpoIIIE_N PF12538.3 ETO30058.1 - 0.015 15.3 1.6 0.016 15.3 0.1 1.8 2 0 0 2 2 2 0 DNA transporter DUF2758 PF10957.3 ETO30058.1 - 0.11 12.2 1.9 0.12 12.2 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2758) CH PF00307.26 ETO30059.1 - 5.4e-10 39.2 0.0 7.7e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.6 ETO30059.1 - 0.0025 17.8 0.0 0.024 14.6 0.0 2.1 1 1 0 1 1 1 1 CDC24 Calponin PARG_cat PF05028.9 ETO30060.1 - 0.007 15.6 0.3 0.01 15.1 0.2 1.2 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) PARG_cat PF05028.9 ETO30061.1 - 1.1e-61 208.9 2.4 1.4e-34 119.9 0.3 2.2 2 0 0 2 2 2 2 Poly (ADP-ribose) glycohydrolase (PARG) AKAP_110 PF05716.8 ETO30061.1 - 5.3e-05 21.4 0.1 8e-05 20.8 0.1 1.2 1 0 0 1 1 1 1 A-kinase anchor protein 110 kDa (AKAP 110) DUF3816 PF12822.2 ETO30061.1 - 0.86 9.4 5.3 1.5 8.6 3.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) AAA_11 PF13086.1 ETO30062.1 - 3.7e-09 36.5 5.4 1.1e-08 34.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 ETO30062.1 - 4.9e-07 29.4 0.2 9.4e-07 28.5 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 ETO30062.1 - 0.00014 21.7 0.3 0.14 12.0 0.0 2.4 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_30 PF13604.1 ETO30062.1 - 0.00045 19.8 0.0 0.00073 19.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ETO30062.1 - 0.0036 17.4 0.2 0.012 15.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 ETO30062.1 - 0.0045 16.7 0.0 0.0099 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.7 ETO30062.1 - 0.0096 15.5 0.1 0.94 9.1 0.0 2.8 3 0 0 3 3 3 1 NACHT domain AAA PF00004.24 ETO30062.1 - 0.015 15.5 0.1 0.042 14.0 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 ETO30062.1 - 0.044 13.1 0.0 0.082 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETO30062.1 - 0.053 13.5 0.0 0.13 12.2 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain DUF4047 PF13256.1 ETO30063.1 - 0.093 12.6 4.1 0.17 11.8 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) UBA_4 PF14555.1 ETO30064.1 - 6.6e-06 25.5 1.0 0.051 13.1 0.0 2.3 2 0 0 2 2 2 2 UBA-like domain LysM PF01476.15 ETO30064.1 - 0.025 14.4 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 LysM domain TLD PF07534.11 ETO30065.1 - 7.7e-17 61.5 2.3 7.7e-17 61.5 1.6 1.9 2 0 0 2 2 2 1 TLD CECR6_TMEM121 PF14997.1 ETO30066.1 - 0.044 13.3 1.8 0.061 12.9 1.2 1.1 1 0 0 1 1 1 0 CECR6/TMEM121 family Mit_KHE1 PF10173.4 ETO30067.1 - 0.42 10.4 2.5 0.3 10.9 0.4 1.6 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related EST1 PF10374.4 ETO30068.1 - 1.5 8.8 8.8 5.7 6.9 1.5 2.4 1 1 1 2 2 2 0 Telomerase activating protein Est1 Internalin_N PF12354.3 ETO30069.1 - 0.13 11.8 0.5 0.28 10.8 0.3 1.5 1 0 0 1 1 1 0 Bacterial adhesion/invasion protein N terminal WD40 PF00400.27 ETO30070.1 - 6.5e-80 260.4 12.3 1e-13 50.5 0.0 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO30070.1 - 1.6e-09 36.4 9.7 0.034 12.2 0.0 4.6 2 2 3 5 5 5 4 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO30070.1 - 7.6e-08 32.2 13.6 0.001 19.1 0.1 6.4 8 0 0 8 8 8 3 Kelch motif Cytochrom_D1 PF02239.11 ETO30070.1 - 1.7e-06 26.5 0.8 0.0056 15.0 0.1 3.4 2 1 1 4 4 4 3 Cytochrome D1 heme domain Kelch_4 PF13418.1 ETO30070.1 - 0.00022 20.9 4.1 0.016 14.9 0.0 4.4 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO30070.1 - 0.00048 19.6 6.8 0.021 14.3 0.1 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO30070.1 - 0.002 18.0 1.5 0.68 9.9 0.1 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO30070.1 - 0.0038 16.9 1.1 3 7.7 0.1 3.8 3 0 0 3 3 3 1 Kelch motif Resistin PF06954.6 ETO30070.1 - 0.032 14.4 0.0 50 4.2 0.0 3.7 2 1 1 3 3 3 0 Resistin Kelch_3 PF13415.1 ETO30070.1 - 0.11 12.6 0.0 0.61 10.3 0.0 2.4 2 0 0 2 2 1 0 Galactose oxidase, central domain CW_binding_1 PF01473.15 ETO30070.1 - 6.6 7.0 10.3 1.8 8.8 3.8 2.9 2 0 0 2 2 1 0 Putative cell wall binding repeat DUF2489 PF10675.4 ETO30071.1 - 0.033 13.8 0.1 0.095 12.3 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2489) Ribosomal_L10 PF00466.15 ETO30072.1 - 0.0011 18.8 0.1 0.0016 18.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 CtIP_N PF10482.4 ETO30072.1 - 0.042 13.6 0.9 0.05 13.3 0.7 1.1 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain DUF2093 PF09866.4 ETO30072.1 - 0.12 11.5 0.1 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2093) DUF1825 PF08855.5 ETO30072.1 - 0.12 12.3 1.0 0.14 12.2 0.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1825) EnY2 PF10163.4 ETO30073.1 - 0.0041 17.0 3.1 0.0062 16.4 2.2 1.4 1 0 0 1 1 1 1 Transcription factor e(y)2 ARGLU PF15346.1 ETO30073.1 - 0.084 12.6 15.4 0.11 12.3 10.7 1.1 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 DUF1378 PF07125.6 ETO30073.1 - 0.15 11.9 0.2 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) DUF733 PF05306.6 ETO30073.1 - 1.3 9.3 6.9 0.067 13.4 1.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF733) DUF2681 PF10883.3 ETO30073.1 - 2.6 8.2 14.1 1.4 9.1 7.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) Selenoprotein_S PF06936.6 ETO30073.1 - 4.3 6.8 9.8 6.3 6.2 6.8 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) MRP-S26 PF14943.1 ETO30073.1 - 6 6.3 18.2 6.1 6.3 12.0 1.5 1 1 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF2408 PF10303.4 ETO30074.1 - 0.0048 16.9 4.5 0.0048 16.9 3.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2408) DUF1515 PF07439.6 ETO30074.1 - 0.0096 15.7 1.9 0.012 15.4 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1515) WEMBL PF05701.6 ETO30074.1 - 0.052 12.0 10.9 0.052 12.0 7.5 1.0 1 0 0 1 1 1 0 Weak chloroplast movement under blue light FlaC_arch PF05377.6 ETO30074.1 - 0.057 13.3 3.4 0.94 9.4 2.1 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) GMP_PDE_delta PF05351.6 ETO30074.1 - 0.15 11.8 1.6 0.17 11.6 1.1 1.2 1 0 0 1 1 1 0 GMP-PDE, delta subunit Filo_VP35 PF02097.10 ETO30074.1 - 0.16 11.1 3.9 0.19 10.9 2.7 1.0 1 0 0 1 1 1 0 Filoviridae VP35 DUF1664 PF07889.7 ETO30074.1 - 0.27 11.0 3.1 0.32 10.8 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF148 PF02520.12 ETO30074.1 - 0.31 10.8 7.9 0.75 9.6 5.5 1.8 1 1 0 1 1 1 0 Domain of unknown function DUF148 Frigida PF07899.6 ETO30074.1 - 1 8.0 7.2 1 8.0 4.7 1.3 1 1 0 1 1 1 0 Frigida-like protein GBP_C PF02841.9 ETO30074.1 - 2.6 7.1 13.1 5.4 6.1 9.1 1.5 1 1 0 1 1 1 0 Guanylate-binding protein, C-terminal domain V_ATPase_I PF01496.14 ETO30074.1 - 3.7 5.2 9.0 3.8 5.2 6.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 ETO30074.1 - 3.8 7.0 10.8 4.6 6.7 7.5 1.1 1 0 0 1 1 1 0 IncA protein Fib_alpha PF08702.5 ETO30074.1 - 3.9 7.5 8.8 7.7 6.6 6.1 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF2951 PF11166.3 ETO30074.1 - 5.6 6.8 10.7 0.8 9.5 4.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) XhlA PF10779.4 ETO30074.1 - 6.5 6.7 8.6 5.2 7.0 5.0 1.8 1 1 0 1 1 1 0 Haemolysin XhlA DUF4200 PF13863.1 ETO30074.1 - 9 6.2 17.7 13 5.7 12.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) RabGAP-TBC PF00566.13 ETO30075.1 - 5.5e-49 166.5 3.6 7.5e-49 166.0 2.5 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ABC2_membrane PF01061.19 ETO30076.1 - 6.9e-25 87.4 17.3 6.9e-25 87.4 12.0 1.5 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.7 ETO30076.1 - 0.001 18.7 2.0 0.0014 18.2 0.1 2.2 3 0 0 3 3 3 1 CDR ABC transporter ABC2_membrane_2 PF12679.2 ETO30076.1 - 0.31 9.8 16.4 0.097 11.5 7.9 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein ABC2_membrane_3 PF12698.2 ETO30076.1 - 0.32 10.0 27.2 0.082 11.9 16.1 2.0 1 1 1 2 2 2 0 ABC-2 family transporter protein IncA PF04156.9 ETO30076.1 - 2.2 7.8 4.7 5.2 6.6 3.3 1.6 1 0 0 1 1 1 0 IncA protein G6PD_C PF02781.11 ETO30078.1 - 1e-105 352.8 0.0 1.4e-105 352.3 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 ETO30078.1 - 5.5e-31 108.2 0.1 1.1e-30 107.2 0.0 1.5 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain CPSF_A PF03178.10 ETO30080.1 - 9.8e-35 120.1 0.2 1.1e-33 116.7 0.0 2.4 2 1 0 2 2 2 1 CPSF A subunit region Kelch_3 PF13415.1 ETO30080.1 - 0.16 12.1 0.4 4 7.7 0.0 2.8 3 0 0 3 3 3 0 Galactose oxidase, central domain MMS1_N PF10433.4 ETO30081.1 - 2.6e-40 138.0 3.5 3.3e-38 131.0 1.4 2.7 2 1 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term Nucleoplasmin PF03066.10 ETO30081.1 - 0.0015 18.1 1.0 0.0015 18.1 0.7 2.5 2 0 0 2 2 2 1 Nucleoplasmin Sigma70_ner PF04546.8 ETO30081.1 - 0.0037 16.9 16.2 0.2 11.2 4.1 2.2 2 0 0 2 2 2 2 Sigma-70, non-essential region RXT2_N PF08595.6 ETO30081.1 - 1.1 9.0 11.6 0.31 10.8 3.5 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal Tom22 PF04281.8 ETO30081.1 - 3.9 6.9 16.8 1.6 8.2 3.6 2.6 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 ETRAMP PF09716.5 ETO30082.1 - 0.085 12.8 0.0 0.18 11.8 0.0 1.6 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Methyltransf_9 PF08003.6 ETO30082.1 - 0.15 10.7 1.2 0.44 9.1 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1698) MFS_1 PF07690.11 ETO30084.1 - 5.6e-28 97.6 19.2 6.6e-28 97.4 13.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETO30084.1 - 2.2e-12 46.2 0.9 3.6e-12 45.5 0.6 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 ETO30084.1 - 6.3e-07 27.8 17.1 7.9e-07 27.4 1.6 3.5 3 1 1 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family Menin PF05053.8 ETO30084.1 - 1.7 6.7 4.0 2.2 6.3 2.8 1.1 1 0 0 1 1 1 0 Menin OATP PF03137.15 ETO30085.1 - 9.5e-05 20.6 2.0 9.5e-05 20.6 1.4 1.9 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family EII-Sor PF03609.9 ETO30085.1 - 0.0047 16.2 4.4 0.048 12.9 0.0 2.6 1 1 2 3 3 3 1 PTS system sorbose-specific iic component YwiC PF14256.1 ETO30085.1 - 0.024 14.7 0.3 0.024 14.7 0.2 3.3 2 2 1 3 3 3 0 YwiC-like protein DUF961 PF06125.6 ETO30086.1 - 0.14 12.3 1.0 0.31 11.2 0.7 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF961) RAP1 PF07218.6 ETO30086.1 - 0.31 9.0 15.9 0.4 8.7 11.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CDC27 PF09507.5 ETO30086.1 - 3.4 6.7 29.8 4.2 6.4 20.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Spc97_Spc98 PF04130.8 ETO30087.1 - 2.5e-09 36.0 10.9 2.5e-09 36.0 7.5 2.1 2 0 0 2 2 2 2 Spc97 / Spc98 family Orthopox_A5L PF06193.6 ETO30087.1 - 0.05 13.5 1.5 0.21 11.4 1.0 2.0 2 1 0 2 2 2 0 Orthopoxvirus A5L protein-like MutS_III PF05192.13 ETO30087.1 - 0.086 12.6 0.3 0.12 12.1 0.2 1.3 1 0 0 1 1 1 0 MutS domain III DUF1216 PF06746.6 ETO30087.1 - 0.15 11.7 2.5 0.3 10.8 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) Bacillus_HBL PF05791.6 ETO30087.1 - 1.8 7.9 5.5 23 4.2 3.8 2.4 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Bud13 PF09736.4 ETO30088.1 - 0.57 10.4 10.5 0.095 12.9 4.6 1.6 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Tir_receptor_C PF07489.6 ETO30088.1 - 5.2 6.7 8.6 7.4 6.2 5.9 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus DUF4661 PF15576.1 ETO30088.1 - 5.6 6.5 5.5 7.1 6.2 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) DUF4539 PF15072.1 ETO30089.1 - 6.5e-08 32.1 0.6 1.4e-07 31.1 0.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4539) TPR_12 PF13424.1 ETO30090.1 - 0.0057 16.5 2.0 0.037 13.9 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO30090.1 - 0.17 11.5 1.6 23 4.8 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat MU117 PF15474.1 ETO30090.1 - 0.29 11.6 4.4 0.8 10.2 3.0 1.8 2 0 0 2 2 2 0 Meiotically up-regulated gene family Metallophos PF00149.23 ETO30091.1 - 1.2e-26 93.3 0.0 1.6e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Sulfatase PF00884.18 ETO30092.1 - 5.4e-20 71.7 0.0 3.1e-19 69.2 0.0 2.0 2 0 0 2 2 2 1 Sulfatase DUF229 PF02995.12 ETO30092.1 - 3.6e-08 32.2 0.0 4.8e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF3784 PF12650.2 ETO30092.1 - 2.5 8.1 7.8 1.3 9.0 0.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3784) AAA_4 PF04326.9 ETO30093.1 - 2.1e-09 37.5 0.1 6.5e-09 35.9 0.1 1.8 1 0 0 1 1 1 1 Divergent AAA domain Suf PF05843.9 ETO30093.1 - 0.0069 16.1 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Uds1 PF15456.1 ETO30093.1 - 0.62 10.0 4.1 0.27 11.2 0.8 1.8 2 0 0 2 2 2 0 Up-regulated During Septation TPR_11 PF13414.1 ETO30094.1 - 7e-26 89.6 12.4 2.7e-12 46.1 0.9 3.4 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 ETO30094.1 - 6.9e-15 53.6 9.7 0.0074 16.1 0.0 4.9 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO30094.1 - 1.8e-14 52.9 0.3 0.0023 18.4 0.0 4.6 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO30094.1 - 4.5e-14 51.3 15.5 0.0005 19.5 0.1 5.5 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO30094.1 - 3.6e-13 48.2 5.5 0.0011 18.6 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO30094.1 - 3.8e-13 48.4 7.9 0.00025 21.0 0.1 5.4 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO30094.1 - 7.5e-13 48.6 0.2 0.00012 22.3 0.3 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO30094.1 - 1.3e-12 47.4 10.4 0.00016 21.5 0.0 4.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO30094.1 - 3.1e-11 43.6 0.7 1.4e-05 25.5 0.1 4.0 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO30094.1 - 3.5e-06 26.4 1.5 1.2 9.1 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO30094.1 - 5.9e-06 26.4 2.5 1.3 9.6 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO30094.1 - 7.7e-06 25.6 0.8 0.077 12.9 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETO30094.1 - 6.8e-05 22.6 0.7 0.75 9.6 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO30094.1 - 0.00068 19.4 2.9 0.062 13.1 0.1 2.6 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat SNAP PF14938.1 ETO30094.1 - 0.00083 18.5 1.3 0.0095 15.1 0.6 2.3 2 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP NARP1 PF12569.3 ETO30094.1 - 0.001 17.9 3.1 0.0017 17.1 1.4 1.8 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 Apc3 PF12895.2 ETO30094.1 - 0.002 18.1 7.7 0.033 14.3 2.7 2.9 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 ETO30094.1 - 0.0067 16.2 1.7 13 5.7 0.0 3.5 2 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain FAT PF02259.18 ETO30094.1 - 0.03 13.3 2.8 2.8 6.8 1.9 2.4 1 1 0 1 1 1 0 FAT domain NTase_sub_bind PF08780.6 ETO30094.1 - 0.044 13.5 1.5 5.6 6.7 0.0 2.9 4 0 0 4 4 3 0 Nucleotidyltransferase substrate binding protein like Sel1 PF08238.7 ETO30094.1 - 0.08 13.6 4.2 40 5.0 0.0 3.8 4 0 0 4 4 4 0 Sel1 repeat SHNi-TPR PF10516.4 ETO30094.1 - 0.093 11.9 2.0 6.8 6.0 0.0 3.5 3 1 1 4 4 4 0 SHNi-TPR TOM20_plant PF06552.7 ETO30094.1 - 0.2 11.2 2.9 3 7.3 0.3 2.6 1 1 2 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 Syntaxin_2 PF14523.1 ETO30094.1 - 3.8 7.6 5.2 7.4 6.6 0.5 2.3 2 0 0 2 2 2 0 Syntaxin-like protein PDEase_I PF00233.14 ETO30095.1 - 2.1e-58 197.8 0.0 9.7e-58 195.7 0.0 2.1 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 ETO30095.1 - 0.034 14.1 0.0 0.091 12.7 0.0 1.8 1 0 0 1 1 1 0 HD domain Pkinase PF00069.20 ETO30097.1 - 2e-38 132.0 0.0 4.8e-38 130.7 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO30097.1 - 7.5e-27 94.0 0.0 1.2e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4381 PF14316.1 ETO30099.1 - 0.042 13.9 0.3 0.074 13.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF2231 PF09990.4 ETO30099.1 - 0.045 14.1 0.3 0.045 14.1 0.2 2.4 3 0 0 3 3 3 0 Predicted membrane protein (DUF2231) XhlA PF10779.4 ETO30099.1 - 5.4 6.9 7.1 0.38 10.6 1.4 1.7 2 0 0 2 2 2 0 Haemolysin XhlA Tetraspannin PF00335.15 ETO30100.1 - 1.4e-23 83.3 16.6 1.8e-23 83.0 11.5 1.1 1 0 0 1 1 1 1 Tetraspanin family SLAC1 PF03595.12 ETO30100.1 - 0.0053 15.4 8.4 0.0053 15.4 5.8 1.9 2 0 0 2 2 2 1 Voltage-dependent anion channel MSC PF09402.5 ETO30100.1 - 0.015 13.9 0.2 0.53 8.9 0.0 2.2 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain SUR7 PF06687.7 ETO30100.1 - 0.065 12.7 9.9 1.1 8.8 0.5 2.3 1 1 1 2 2 2 0 SUR7/PalI family TarH PF02203.10 ETO30100.1 - 0.26 11.1 7.5 4.7 7.0 0.3 2.5 2 0 0 2 2 2 0 Tar ligand binding domain homologue Mid2 PF04478.7 ETO30100.1 - 0.39 10.1 3.5 2.5 7.4 0.1 2.4 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor DUF2207 PF09972.4 ETO30100.1 - 0.6 8.6 8.7 3.6 6.0 5.4 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Vma12 PF11712.3 ETO30100.1 - 1.3 8.6 3.4 3.5 7.3 2.4 1.8 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF202 PF02656.10 ETO30100.1 - 2.9 8.1 10.0 6.1 7.1 0.1 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF202) PAP_assoc PF03828.14 ETO30101.1 - 4.8e-09 36.0 2.6 2.8e-06 27.1 0.4 3.0 2 0 0 2 2 2 2 Cid1 family poly A polymerase PAP_central PF04928.12 ETO30101.1 - 0.0022 16.8 0.1 0.1 11.3 0.0 2.3 2 0 0 2 2 2 2 Poly(A) polymerase central domain tRNA_NucTransf2 PF09249.6 ETO30101.1 - 0.035 13.9 1.7 0.046 13.6 0.1 2.1 2 0 0 2 2 2 0 tRNA nucleotidyltransferase, second domain NTP_transf_2 PF01909.18 ETO30102.1 - 9.8e-06 25.8 0.0 2.2e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF2067 PF09840.4 ETO30104.1 - 0.0045 16.5 0.1 0.0061 16.0 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2067) DX PF01666.12 ETO30104.1 - 0.036 14.5 1.3 0.077 13.4 0.9 1.5 1 0 0 1 1 1 0 DX module Paramyxo_C PF01692.13 ETO30104.1 - 0.14 11.8 1.2 0.2 11.2 0.8 1.1 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c Rft-1 PF04506.8 ETO30105.1 - 0.086 11.1 0.0 0.11 10.9 0.0 1.0 1 0 0 1 1 1 0 Rft protein DUF2407_C PF13373.1 ETO30106.1 - 0.00043 20.2 0.0 0.00072 19.4 0.0 1.3 1 0 0 1 1 1 1 DUF2407 C-terminal domain Zip PF02535.17 ETO30108.1 - 2.5 7.0 4.6 9.1 5.1 3.2 1.8 1 1 0 1 1 1 0 ZIP Zinc transporter Paramyxo_ncap PF00973.14 ETO30108.1 - 3.1 6.3 6.5 5.1 5.6 4.5 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Sporozoite_P67 PF05642.6 ETO30108.1 - 5 4.8 7.3 7.8 4.2 5.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Daxx PF03344.10 ETO30108.1 - 5.8 5.2 18.8 11 4.3 13.0 1.4 1 0 0 1 1 1 0 Daxx Family WEMBL PF05701.6 ETO30109.1 - 0.0037 15.8 6.6 0.0043 15.5 4.6 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Fmp27_WPPW PF10359.4 ETO30109.1 - 0.013 13.9 8.6 0.014 13.8 6.0 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain HSBP1 PF06825.7 ETO30109.1 - 0.022 14.3 6.4 0.059 12.9 4.5 1.8 1 1 0 1 1 1 0 Heat shock factor binding protein 1 DUF3245 PF11595.3 ETO30109.1 - 0.032 14.5 7.3 0.039 14.2 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) TACC PF05010.9 ETO30109.1 - 0.034 13.9 7.3 0.048 13.4 5.1 1.3 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) DUF2421 PF10334.4 ETO30109.1 - 0.042 13.4 0.3 0.05 13.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2421) DUF972 PF06156.8 ETO30109.1 - 0.059 13.7 7.4 0.073 13.4 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF948 PF06103.6 ETO30109.1 - 0.071 12.9 4.6 0.078 12.8 2.5 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) PRKCSH-like PF12999.2 ETO30109.1 - 0.11 12.0 4.8 0.13 11.8 3.3 1.1 1 0 0 1 1 1 0 Glucosidase II beta subunit-like PYST-C1 PF09690.5 ETO30109.1 - 0.12 11.9 2.4 0.22 11.1 1.7 1.5 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) Tweety PF04906.8 ETO30109.1 - 0.13 10.6 2.4 0.15 10.4 1.7 1.0 1 0 0 1 1 1 0 Tweety DUF3414 PF11894.3 ETO30109.1 - 0.13 9.0 3.3 0.14 8.9 2.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3414) RmuC PF02646.11 ETO30109.1 - 0.15 10.8 6.5 0.19 10.5 4.5 1.3 1 1 0 1 1 1 0 RmuC family Streptin-Immun PF11083.3 ETO30109.1 - 0.15 12.0 5.5 0.51 10.3 3.8 1.8 1 1 0 1 1 1 0 Lantibiotic streptin immunity protein APG6 PF04111.7 ETO30109.1 - 0.23 10.4 10.2 0.24 10.4 7.1 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 HlyD_2 PF12700.2 ETO30109.1 - 0.25 10.4 4.4 0.27 10.3 3.1 1.1 1 0 0 1 1 1 0 HlyD family secretion protein DUF883 PF05957.8 ETO30109.1 - 0.29 11.5 2.5 13 6.2 0.5 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DSHCT PF08148.7 ETO30109.1 - 0.31 10.2 3.2 0.55 9.4 0.7 1.9 1 1 1 2 2 2 0 DSHCT (NUC185) domain SDP_N PF12278.3 ETO30109.1 - 0.34 10.5 6.9 0.39 10.3 4.8 1.1 1 0 0 1 1 1 0 Sex determination protein N terminal EAP30 PF04157.11 ETO30109.1 - 0.34 10.0 4.6 0.24 10.5 2.0 1.5 1 1 0 1 1 1 0 EAP30/Vps36 family SlyX PF04102.7 ETO30109.1 - 0.39 11.1 7.9 0.31 11.4 3.8 2.0 1 1 1 2 2 2 0 SlyX Allexi_40kDa PF05549.6 ETO30109.1 - 0.39 9.9 4.0 0.48 9.6 2.8 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF848 PF05852.6 ETO30109.1 - 0.51 10.1 7.5 0.63 9.8 5.2 1.0 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) GvpK PF05121.7 ETO30109.1 - 0.81 9.5 6.6 1 9.1 4.1 1.5 1 1 1 2 2 2 0 Gas vesicle protein K Occludin_ELL PF07303.8 ETO30109.1 - 1.5 9.6 8.8 3.1 8.5 3.0 2.0 1 1 1 2 2 2 0 Occludin homology domain FlaC_arch PF05377.6 ETO30109.1 - 1.7 8.6 5.7 3.5 7.6 3.7 1.8 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) V_ATPase_I PF01496.14 ETO30109.1 - 3.2 5.4 7.4 3.5 5.3 5.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 ETO30109.1 - 3.2 6.0 7.4 3.5 5.9 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4337 PF14235.1 ETO30109.1 - 5.7 6.7 7.3 7.3 6.3 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) IncA PF04156.9 ETO30109.1 - 5.7 6.4 7.5 7.9 6.0 5.2 1.3 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 ETO30110.1 - 0.14 10.0 12.7 0.046 11.5 7.0 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1003 PF06210.6 ETO30110.1 - 5.9 6.8 8.1 0.67 9.8 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) Spc24 PF08286.6 ETO30110.1 - 6.7 6.4 21.2 0.093 12.4 1.1 3.7 3 1 1 4 4 4 0 Spc24 subunit of Ndc80 Mucin PF01456.12 ETO30111.1 - 0.0038 17.0 8.2 0.0051 16.5 5.7 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein ABC2_membrane_3 PF12698.2 ETO30111.1 - 0.38 9.7 2.9 0.56 9.1 2.0 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein TMEM154 PF15102.1 ETO30111.1 - 0.53 9.9 11.7 2.2 8.0 8.1 1.9 1 1 0 1 1 1 0 TMEM154 protein family Dicty_REP PF05086.7 ETO30111.1 - 0.9 7.2 6.1 1 7.0 4.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Herpes_BLLF1 PF05109.8 ETO30111.1 - 3.3 5.5 16.8 4.2 5.2 11.6 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Oxidored_q1_C PF01010.14 ETO30111.1 - 6.3 6.2 8.3 0.59 9.6 2.2 1.8 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus PXA PF02194.10 ETO30112.1 - 3.9e-09 36.3 0.6 1.5e-08 34.4 0.0 1.9 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 ETO30113.1 - 2.1e-13 50.3 0.5 2.1e-13 50.3 0.3 2.6 2 1 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 ETO30113.1 - 9.2e-10 38.3 0.6 9.2e-10 38.3 0.4 2.5 3 0 0 3 3 3 1 PX domain CENP-F_leu_zip PF10473.4 ETO30114.1 - 0.15 11.8 28.3 0.22 11.3 9.8 2.6 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF763 PF05559.6 ETO30114.1 - 0.35 9.7 11.0 0.017 14.0 3.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF763) Val_tRNA-synt_C PF10458.4 ETO30114.1 - 0.92 9.6 5.0 2.8 8.0 0.2 3.3 3 1 1 4 4 4 0 Valyl tRNA synthetase tRNA binding arm Tweety PF04906.8 ETO30114.1 - 2.3 6.5 9.8 0.27 9.5 3.1 2.1 2 0 0 2 2 2 0 Tweety DUF972 PF06156.8 ETO30114.1 - 2.8 8.3 23.6 0.17 12.2 2.7 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Phage_GP20 PF06810.6 ETO30114.1 - 3.7 6.9 17.0 0.14 11.5 1.3 3.2 2 1 1 3 3 3 0 Phage minor structural protein GP20 Rootletin PF15035.1 ETO30114.1 - 4.1 7.3 24.5 1.9 8.4 2.4 2.8 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion FtsL PF04999.8 ETO30114.1 - 5.9 6.6 10.3 0.58 9.8 0.2 3.0 2 1 0 2 2 2 0 Cell division protein FtsL DUF3186 PF11382.3 ETO30114.1 - 7.5 5.5 8.0 1.7 7.7 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3186) DUF4618 PF15397.1 ETO30115.1 - 0.00034 20.0 5.5 0.0004 19.8 3.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) FlgN PF05130.7 ETO30115.1 - 0.002 18.4 1.9 0.0024 18.0 1.3 1.1 1 0 0 1 1 1 1 FlgN protein OmpH PF03938.9 ETO30115.1 - 0.0036 17.2 1.0 0.0036 17.2 0.7 1.1 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Takusan PF04822.8 ETO30115.1 - 0.011 15.4 1.8 0.011 15.4 1.2 1.1 1 0 0 1 1 1 0 Takusan 60KD_IMP PF02096.15 ETO30115.1 - 0.012 15.3 1.4 0.013 15.1 1.0 1.1 1 0 0 1 1 1 0 60Kd inner membrane protein WTF PF03303.8 ETO30115.1 - 0.025 14.0 0.1 0.025 14.0 0.1 1.1 1 0 0 1 1 1 0 WTF protein Use1 PF09753.4 ETO30115.1 - 0.025 14.0 1.5 0.03 13.7 1.0 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 DUF3713 PF12506.3 ETO30115.1 - 0.026 14.5 1.2 0.033 14.2 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3713) Remorin_C PF03763.8 ETO30115.1 - 0.033 13.7 2.1 0.046 13.2 1.4 1.2 1 0 0 1 1 1 0 Remorin, C-terminal region Kinesin-relat_1 PF12711.2 ETO30115.1 - 0.037 14.4 2.7 0.042 14.2 1.9 1.1 1 0 0 1 1 1 0 Kinesin motor FimP PF09766.4 ETO30115.1 - 0.042 12.9 1.2 0.048 12.7 0.8 1.1 1 0 0 1 1 1 0 Fms-interacting protein Alpha-2-MRAP_C PF06401.6 ETO30115.1 - 0.043 13.6 0.3 0.043 13.6 0.2 1.1 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain WCOR413 PF05562.6 ETO30115.1 - 0.046 13.2 0.0 0.052 13.0 0.0 1.0 1 0 0 1 1 1 0 Cold acclimation protein WCOR413 LCD1 PF09798.4 ETO30115.1 - 0.056 11.4 5.9 0.062 11.2 4.1 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF4200 PF13863.1 ETO30115.1 - 0.06 13.3 6.3 0.085 12.8 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF2408 PF10303.4 ETO30115.1 - 0.078 13.0 1.5 0.074 13.1 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Phage_Mu_Gam PF07352.7 ETO30115.1 - 0.082 12.4 2.3 0.11 12.0 1.6 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein DUF651 PF04895.7 ETO30115.1 - 0.091 12.3 1.1 0.12 12.0 0.8 1.1 1 0 0 1 1 1 0 Archaeal protein of unknown function (DUF651) TMF_TATA_bd PF12325.3 ETO30115.1 - 0.099 12.3 6.5 0.13 11.9 4.5 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF912 PF06024.7 ETO30115.1 - 0.14 12.2 0.5 0.16 12.0 0.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Syntaxin-6_N PF09177.6 ETO30115.1 - 0.22 11.9 1.8 0.28 11.6 1.3 1.2 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Pox_A_type_inc PF04508.7 ETO30115.1 - 0.24 11.2 2.2 14 5.7 0.1 2.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF2228 PF10228.4 ETO30115.1 - 0.27 10.7 1.8 0.28 10.6 1.3 1.0 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) PCRF PF03462.13 ETO30115.1 - 0.33 10.6 1.9 0.4 10.4 1.3 1.2 1 0 0 1 1 1 0 PCRF domain Prefoldin PF02996.12 ETO30115.1 - 0.36 10.4 5.4 0.54 9.9 3.7 1.3 1 0 0 1 1 1 0 Prefoldin subunit CHD5 PF04420.9 ETO30115.1 - 0.36 10.4 4.1 1.5 8.4 1.9 1.9 1 1 1 2 2 2 0 CHD5-like protein FliT PF05400.8 ETO30115.1 - 0.46 10.9 6.1 0.57 10.6 4.2 1.1 1 0 0 1 1 1 0 Flagellar protein FliT THOC7 PF05615.8 ETO30115.1 - 0.62 10.3 4.6 0.7 10.1 3.2 1.1 1 0 0 1 1 1 0 Tho complex subunit 7 IncA PF04156.9 ETO30115.1 - 0.85 9.1 8.2 0.53 9.8 4.9 1.3 1 1 0 1 1 1 0 IncA protein DUF793 PF05633.6 ETO30115.1 - 1.3 7.6 6.0 0.26 10.0 2.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF793) SseC PF04888.7 ETO30115.1 - 1.8 7.8 6.3 2.1 7.6 4.4 1.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Synaptobrevin PF00957.16 ETO30115.1 - 5.5 6.6 8.8 0.15 11.7 0.6 2.0 1 1 1 2 2 2 0 Synaptobrevin Mitofilin PF09731.4 ETO30115.1 - 9.2 4.7 7.5 11 4.4 5.2 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein His_Phos_1 PF00300.17 ETO30116.1 - 0.0015 18.6 0.0 0.0018 18.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) FlbD PF06289.6 ETO30116.1 - 0.19 11.1 0.6 0.43 10.0 0.0 1.8 2 0 0 2 2 2 0 Flagellar protein (FlbD) CS PF04969.11 ETO30118.1 - 1.2e-10 41.7 0.2 1.7e-10 41.2 0.2 1.3 1 0 0 1 1 1 1 CS domain HSP20 PF00011.16 ETO30118.1 - 0.017 14.9 0.1 0.044 13.6 0.0 1.7 1 0 0 1 1 1 0 Hsp20/alpha crystallin family MMR1 PF08505.5 ETO30118.1 - 0.027 14.5 3.9 0.031 14.3 2.7 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein EF-hand_1 PF00036.27 ETO30119.1 - 2.9e-19 66.8 7.7 1.1e-05 24.3 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 ETO30119.1 - 3.9e-16 58.9 2.6 7.4e-10 38.8 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO30119.1 - 2.5e-14 51.7 2.0 0.00076 19.1 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain CAP_GLY PF01302.20 ETO30119.1 - 8.8e-13 47.7 0.9 1.8e-12 46.7 0.6 1.6 1 0 0 1 1 1 1 CAP-Gly domain EF-hand_5 PF13202.1 ETO30119.1 - 1.6e-11 42.9 6.9 0.00042 19.5 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 ETO30119.1 - 1.8e-11 43.4 4.4 0.0038 16.8 0.0 4.1 3 1 1 4 4 4 3 EF-hand domain pair Cbl_N2 PF02761.9 ETO30119.1 - 0.00027 20.9 1.3 0.67 10.0 0.1 2.3 2 0 0 2 2 2 2 CBL proto-oncogene N-terminus, EF hand-like domain EF-hand_10 PF14788.1 ETO30119.1 - 0.00029 20.4 0.2 0.15 11.7 0.0 2.9 2 1 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.4 ETO30119.1 - 0.0038 17.2 3.0 0.21 11.6 0.1 2.9 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF3664 PF12406.3 ETO30119.1 - 0.017 15.7 0.2 0.32 11.6 0.1 2.2 2 0 0 2 2 2 0 Surface protein APP_E2 PF12925.2 ETO30119.1 - 0.023 14.2 0.6 0.041 13.4 0.0 1.6 2 0 0 2 2 2 0 E2 domain of amyloid precursor protein LytR_cpsA_psr PF03816.9 ETO30119.1 - 0.029 14.2 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 Cell envelope-related transcriptional attenuator domain C-C_Bond_Lyase PF15617.1 ETO30119.1 - 0.09 11.5 0.1 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 C-C_Bond_Lyase of the TIM-Barrel fold Hint_2 PF13403.1 ETO30119.1 - 0.12 12.3 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 Hint domain EF-hand_4 PF12763.2 ETO30119.1 - 0.18 11.5 1.5 3.5 7.4 0.2 2.8 1 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand adh_short PF00106.20 ETO30122.1 - 1.8e-25 89.7 0.2 2.2e-25 89.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETO30122.1 - 1e-14 54.8 0.0 1.5e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETO30122.1 - 3.3e-08 33.3 0.0 5.4e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETO30122.1 - 0.0048 16.3 0.1 0.0062 16.0 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 ETO30122.1 - 0.0053 16.4 0.3 0.0091 15.6 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 ETO30122.1 - 0.055 12.3 0.1 0.079 11.8 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 2-Hacid_dh_C PF02826.14 ETO30122.1 - 0.12 11.5 0.1 0.19 10.8 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Peptidase_S49_N PF08496.5 ETO30123.1 - 0.11 12.2 0.2 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal COesterase PF00135.23 ETO30124.1 - 7.5e-106 354.9 0.2 1e-105 354.5 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETO30124.1 - 0.0071 15.9 0.0 0.015 14.8 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold PG_binding_1 PF01471.13 ETO30126.1 - 4e-20 71.5 0.1 7.3e-20 70.7 0.1 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Peptidase_M10 PF00413.19 ETO30126.1 - 4.4e-08 32.9 0.0 8e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Matrixin PG_binding_2 PF08823.6 ETO30126.1 - 0.0013 18.7 0.1 0.0032 17.5 0.0 1.6 1 1 0 1 1 1 1 Putative peptidoglycan binding domain PG_binding_3 PF09374.5 ETO30126.1 - 0.006 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Predicted Peptidoglycan domain adh_short PF00106.20 ETO30128.1 - 2.7e-10 40.3 0.0 3.9e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETO30128.1 - 1.6e-06 27.9 0.0 2.4e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 ETO30128.1 - 3.8e-06 26.0 0.2 6.5e-06 25.2 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 ETO30128.1 - 0.0029 17.3 0.2 0.098 12.4 0.0 2.6 3 0 0 3 3 3 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pex14_N PF04695.8 ETO30129.1 - 0.24 11.4 4.4 0.3 11.1 0.5 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Secretin_N_2 PF07655.8 ETO30129.1 - 6.1 7.3 20.5 0.71 10.3 9.8 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain CRM1_C PF08767.6 ETO30130.1 - 0.0098 14.8 2.4 0.012 14.5 1.7 1.2 1 0 0 1 1 1 1 CRM1 C terminal DUF2120 PF09893.4 ETO30130.1 - 0.17 11.8 0.3 0.27 11.1 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) Dynein_light PF01221.13 ETO30131.1 - 5.2e-36 122.5 1.6 5.2e-36 122.5 1.1 2.0 2 0 0 2 2 2 1 Dynein light chain type 1 Aminotran_1_2 PF00155.16 ETO30132.1 - 2.3e-27 95.9 0.5 3.9e-17 62.2 0.1 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II ABC_membrane PF00664.18 ETO30132.1 - 0.023 14.1 1.3 0.035 13.5 0.9 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region Cys_Met_Meta_PP PF01053.15 ETO30132.1 - 0.029 12.6 0.5 0.091 11.0 0.0 1.8 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 ETO30132.1 - 0.063 12.3 0.0 0.09 11.7 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Pkinase PF00069.20 ETO30133.1 - 2.9e-21 75.8 0.0 4e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO30133.1 - 0.044 12.8 0.0 0.12 11.3 0.0 1.8 1 1 0 1 1 1 0 Protein tyrosine kinase PARP PF00644.15 ETO30134.1 - 1.5e-70 236.7 0.0 2.5e-70 236.1 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 ETO30134.1 - 9.4e-36 122.4 0.3 1.5e-35 121.7 0.2 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 ETO30135.1 - 2.3e-22 78.7 1.3 2.3e-22 78.7 0.9 3.6 3 0 0 3 3 3 2 WGR domain BRCT PF00533.21 ETO30135.1 - 5.7e-12 45.6 0.3 2.3e-11 43.6 0.2 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF1835 PF08874.5 ETO30135.1 - 0.017 15.0 1.0 0.049 13.5 0.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) Folate_carrier PF01770.13 ETO30135.1 - 4.5 5.6 6.8 0.81 8.1 0.3 2.2 2 0 0 2 2 2 0 Reduced folate carrier OATP PF03137.15 ETO30135.1 - 9.2 4.1 8.9 0.37 8.7 0.3 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DTW PF03942.10 ETO30139.1 - 2.5e-18 66.0 0.0 2.5e-18 66.0 0.0 2.0 2 0 0 2 2 2 1 DTW domain zf-B_box PF00643.19 ETO30139.1 - 0.089 12.6 1.6 0.21 11.5 1.1 1.7 1 0 0 1 1 1 0 B-box zinc finger Nudix_N_2 PF14803.1 ETO30139.1 - 0.11 12.2 3.2 11 5.8 0.0 2.7 2 0 0 2 2 2 0 Nudix N-terminal PTS_2-RNA PF01885.11 ETO30141.1 - 0.0039 16.5 0.0 0.0064 15.8 0.0 1.3 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF3841 PF12952.2 ETO30141.1 - 0.048 13.1 0.2 0.11 11.9 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3841) Pkinase PF00069.20 ETO30142.1 - 2.6e-23 82.4 0.4 3.3e-23 82.1 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO30142.1 - 6.7e-13 48.3 0.6 1.4e-12 47.2 0.4 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase MerR_1 PF13411.1 ETO30142.1 - 0.081 12.7 0.4 0.16 11.7 0.3 1.5 1 0 0 1 1 1 0 MerR HTH family regulatory protein Pkinase PF00069.20 ETO30143.1 - 7e-37 126.9 0.0 8.4e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO30143.1 - 1.1e-12 47.6 0.1 7e-12 44.9 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 ETO30143.1 - 0.002 17.0 0.2 0.18 10.5 0.1 2.1 2 0 0 2 2 2 2 Poxvirus serine/threonine protein kinase WD40 PF00400.27 ETO30146.1 - 8.4e-72 234.7 20.3 1e-12 47.4 0.0 7.5 8 1 0 8 8 8 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO30146.1 - 4.6e-10 39.5 0.6 1.1e-05 25.2 0.0 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO30146.1 - 1.4e-05 23.4 6.7 0.051 11.7 0.8 3.6 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO30146.1 - 2.9e-05 22.5 0.1 0.00089 17.6 0.0 2.5 1 1 2 3 3 3 1 Cytochrome D1 heme domain DUF1258 PF06869.7 ETO30146.1 - 0.0017 17.4 0.8 0.098 11.7 0.1 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF1258) Str_synth PF03088.11 ETO30146.1 - 0.03 14.3 0.0 0.49 10.4 0.0 2.8 3 0 0 3 3 3 0 Strictosidine synthase PD40 PF07676.7 ETO30146.1 - 0.082 12.6 1.1 1.1e+02 2.6 0.0 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 ETO30147.1 - 2e-84 274.7 27.0 1.8e-12 46.6 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat DUF1258 PF06869.7 ETO30147.1 - 1.7e-07 30.6 11.5 0.013 14.6 0.2 4.8 1 1 4 5 5 5 4 Protein of unknown function (DUF1258) Kelch_4 PF13418.1 ETO30147.1 - 9.3e-07 28.5 0.1 0.00088 18.9 0.0 2.9 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO30147.1 - 1.7e-05 24.8 0.0 5.2e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO30147.1 - 1.7e-05 24.2 0.5 0.00011 21.7 0.1 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETO30147.1 - 1.8e-05 24.7 0.1 1.8e-05 24.7 0.1 5.1 6 1 1 7 7 7 1 Kelch motif Kelch_5 PF13854.1 ETO30147.1 - 3e-05 23.8 0.4 0.00036 20.4 0.4 2.5 2 0 0 2 2 2 1 Kelch motif Nup160 PF11715.3 ETO30147.1 - 0.0027 15.9 0.5 0.0027 15.9 0.4 3.7 1 1 2 4 4 4 1 Nucleoporin Nup120/160 Kelch_2 PF07646.10 ETO30147.1 - 0.006 16.3 0.0 0.039 13.7 0.0 2.5 1 0 0 1 1 1 1 Kelch motif PD40 PF07676.7 ETO30147.1 - 0.01 15.4 3.4 1.2 8.8 0.0 3.7 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 ETO30147.1 - 1.7 8.0 7.2 8.7 5.7 0.0 3.4 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature EF-hand_6 PF13405.1 ETO30150.1 - 0.075 12.9 0.2 5.8 7.0 0.1 2.7 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.1 ETO30150.1 - 0.079 13.1 0.2 2.7 8.2 0.2 2.6 1 1 0 1 1 1 0 EF-hand domain pair TMEM154 PF15102.1 ETO30152.1 - 0.0085 15.8 2.7 0.013 15.1 1.9 1.3 1 0 0 1 1 1 1 TMEM154 protein family CD34_antigen PF06365.7 ETO30152.1 - 0.045 13.4 0.2 0.058 13.0 0.1 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Pkinase PF00069.20 ETO30154.1 - 3.7e-10 39.3 0.0 9.7e-10 38.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO30154.1 - 0.00029 19.9 0.0 0.00057 19.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pneumo_phosprot PF02478.11 ETO30154.1 - 0.55 9.7 4.1 0.75 9.2 2.9 1.2 1 0 0 1 1 1 0 Pneumovirus phosphoprotein Macoilin PF09726.4 ETO30154.1 - 4.2 5.5 13.8 4.8 5.3 9.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Vesiculo_matrix PF06326.7 ETO30155.1 - 0.014 14.8 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Vesiculovirus matrix protein Ank_2 PF12796.2 ETO30156.1 - 4.4e-45 151.9 5.8 7e-18 64.7 0.1 4.0 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 ETO30156.1 - 3.8e-32 108.4 2.8 4e-07 29.5 0.1 5.6 4 2 1 5 5 5 5 Ankyrin repeat Ank_3 PF13606.1 ETO30156.1 - 2.1e-26 89.3 2.7 5.5e-05 23.0 0.0 6.2 5 1 1 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 ETO30156.1 - 2.3e-22 78.9 0.9 4.2e-10 39.8 0.0 4.2 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO30156.1 - 1.6e-21 75.8 1.6 2.7e-06 27.4 0.1 4.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) DUF1985 PF09331.6 ETO30156.1 - 0.13 12.0 0.6 0.77 9.5 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1985) adh_short PF00106.20 ETO30157.1 - 2.7e-23 82.6 0.0 1.3e-13 51.1 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 ETO30157.1 - 4e-11 43.1 0.0 6.6e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 ETO30157.1 - 1.4e-07 31.6 0.0 8.3e-05 22.6 0.0 2.1 2 0 0 2 2 2 2 NADH(P)-binding KR PF08659.5 ETO30157.1 - 1.1e-06 28.4 0.0 5.2e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 ETO30157.1 - 0.0038 16.6 0.1 0.0075 15.7 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DGC PF08859.6 ETO30157.1 - 0.01 15.7 0.6 1.8 8.4 0.0 2.7 2 0 0 2 2 2 0 DGC domain NmrA PF05368.8 ETO30157.1 - 0.015 14.5 0.0 0.029 13.6 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family YMF19 PF02326.10 ETO30157.1 - 1.3 9.5 7.3 9.9 6.8 0.1 2.7 2 0 0 2 2 2 0 Plant ATP synthase F0 EF-hand_1 PF00036.27 ETO30158.1 - 4.6e-20 69.3 9.1 1.6e-06 26.9 0.0 4.6 4 1 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 ETO30158.1 - 6e-20 71.1 3.5 2.1e-10 40.5 0.2 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 ETO30158.1 - 4.2e-16 57.4 4.9 3.7e-05 22.8 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 ETO30158.1 - 5.2e-15 53.9 5.9 9.3e-05 21.9 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 ETO30158.1 - 6.7e-13 48.0 2.9 0.00061 19.3 0.0 4.1 4 0 0 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 ETO30158.1 - 6.6e-05 22.9 4.0 0.13 12.3 0.1 3.2 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 ETO30158.1 - 0.00069 19.3 3.6 0.099 12.3 0.0 3.3 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand DIL PF01843.14 ETO30158.1 - 0.039 13.8 0.1 0.1 12.4 0.1 1.6 2 0 0 2 2 2 0 DIL domain Vezatin PF12632.2 ETO30158.1 - 0.054 12.5 0.1 0.08 12.0 0.0 1.2 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes DUF2315 PF10231.4 ETO30159.1 - 0.013 15.3 0.6 0.019 14.8 0.4 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2315) Endonuc_BglI PF14562.1 ETO30159.1 - 0.037 12.8 0.0 0.045 12.5 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease BglI DNA_pol3_beta_2 PF02767.11 ETO30160.1 - 0.062 13.3 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III beta subunit, central domain Sel1 PF08238.7 ETO30161.1 - 1.5e-14 54.0 2.5 0.00018 22.0 0.0 4.5 3 1 0 3 3 3 3 Sel1 repeat TPR_16 PF13432.1 ETO30161.1 - 0.022 15.4 2.5 0.82 10.4 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO30161.1 - 0.034 14.6 1.0 2.2 8.9 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETO30161.1 - 0.2 11.6 2.0 77 3.5 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat HIT PF01230.18 ETO30162.1 - 6.6e-25 87.5 0.0 1.2e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 ETO30162.1 - 5.5e-11 42.7 0.0 1e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Ras PF00071.17 ETO30163.1 - 1.7e-37 128.3 8.0 3.3e-27 94.8 0.2 3.4 2 1 1 3 3 3 3 Ras family Miro PF08477.8 ETO30163.1 - 2e-08 34.7 2.1 1.3e-05 25.6 1.5 3.2 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 ETO30163.1 - 0.00082 19.3 0.4 0.0083 16.0 0.3 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 ETO30163.1 - 0.0013 18.0 0.7 0.048 12.8 0.2 2.7 2 1 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETO30163.1 - 0.0067 15.5 3.4 1.1 8.3 0.1 2.9 3 1 0 3 3 3 2 Gtr1/RagA G protein conserved region ORF6N PF10543.4 ETO30163.1 - 0.18 11.8 2.0 0.28 11.2 0.1 2.2 2 0 0 2 2 2 0 ORF6N domain adh_short PF00106.20 ETO30164.1 - 2.2e-16 60.2 0.0 4.1e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETO30164.1 - 0.00021 21.0 0.0 0.00036 20.2 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETO30164.1 - 0.016 15.0 0.0 0.055 13.2 0.0 1.8 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETO30164.1 - 0.025 14.0 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETO30164.1 - 0.07 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding zf-C3HC4_3 PF13920.1 ETO30165.1 - 9.7e-10 37.9 21.2 9.7e-10 37.9 14.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Neur_chan_memb PF02932.11 ETO30165.1 - 0.034 14.0 3.3 0.061 13.1 2.2 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region zf-C3HC4_2 PF13923.1 ETO30165.1 - 0.5 10.4 30.1 0.072 13.1 16.5 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prp18 PF02840.10 ETO30165.1 - 0.89 9.3 0.0 0.89 9.3 0.0 2.8 2 1 1 3 3 3 0 Prp18 domain Mgr1 PF08602.5 ETO30165.1 - 2.4 7.1 7.2 3.6 6.5 5.0 1.2 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit TMPIT PF07851.8 ETO30165.1 - 3.7 6.5 7.6 6.6 5.7 5.3 1.4 1 0 0 1 1 1 0 TMPIT-like protein Mnd1 PF03962.10 ETO30166.1 - 0.0089 15.7 5.8 0.0089 15.7 4.0 1.5 2 0 0 2 2 2 1 Mnd1 family HAUS6_N PF14661.1 ETO30166.1 - 0.054 12.8 5.6 0.065 12.5 3.9 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF3573 PF12097.3 ETO30166.1 - 0.2 10.2 2.7 0.22 10.0 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) GAS PF13851.1 ETO30166.1 - 0.78 8.9 13.9 0.059 12.5 5.5 1.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding bZIP_2 PF07716.10 ETO30166.1 - 1.4 8.8 0.0 1.4 8.8 0.0 3.2 2 1 1 3 3 3 0 Basic region leucine zipper DUF2681 PF10883.3 ETO30166.1 - 1.7 8.8 7.8 0.21 11.7 2.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF4407 PF14362.1 ETO30166.1 - 2.4 7.0 6.2 2 7.3 2.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) PilO PF04350.8 ETO30166.1 - 2.5 7.9 6.6 5.6 6.8 4.6 1.6 1 1 0 1 1 1 0 Pilus assembly protein, PilO Ras PF00071.17 ETO30167.1 - 0.00012 21.5 0.0 0.0002 20.7 0.0 1.4 1 0 0 1 1 1 1 Ras family AAA_14 PF13173.1 ETO30167.1 - 0.016 15.1 0.2 0.046 13.6 0.0 1.9 1 1 1 2 2 2 0 AAA domain Menin PF05053.8 ETO30167.1 - 0.37 8.9 6.4 0.59 8.2 4.5 1.4 1 0 0 1 1 1 0 Menin NOA36 PF06524.7 ETO30167.1 - 2.4 7.3 10.6 3.5 6.7 7.4 1.2 1 0 0 1 1 1 0 NOA36 protein GCD14 PF08704.5 ETO30167.1 - 5.9 6.3 6.9 1.7 8.1 2.4 1.7 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit DcpS_C PF11969.3 ETO30168.1 - 6e-12 45.8 0.2 1.6e-11 44.4 0.1 1.7 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DHO_dh PF01180.16 ETO30169.1 - 5.5e-35 120.7 0.0 7e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.10 ETO30169.1 - 0.02 14.0 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase SAM_1 PF00536.25 ETO30170.1 - 3.2e-12 46.4 0.2 5.3e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO30170.1 - 2e-09 37.1 0.1 3.4e-09 36.3 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Mnd1 PF03962.10 ETO30170.1 - 0.032 13.8 10.4 0.043 13.4 7.2 1.2 1 0 0 1 1 1 0 Mnd1 family bZIP_1 PF00170.16 ETO30170.1 - 0.064 13.2 2.1 0.064 13.2 1.5 2.3 2 0 0 2 2 2 0 bZIP transcription factor Syntaxin PF00804.20 ETO30170.1 - 0.1 12.8 3.8 0.22 11.7 2.7 1.5 1 0 0 1 1 1 0 Syntaxin Striatin PF08232.7 ETO30170.1 - 0.15 12.4 6.8 0.23 11.7 4.7 1.3 1 0 0 1 1 1 0 Striatin family Ax_dynein_light PF10211.4 ETO30170.1 - 0.17 11.7 11.5 0.28 10.9 8.0 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain RP-C_C PF11800.3 ETO30170.1 - 0.22 11.2 2.3 0.3 10.7 1.6 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region BBP1_C PF15272.1 ETO30170.1 - 0.3 10.5 5.0 0.43 10.1 3.5 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Microtub_assoc PF07989.6 ETO30170.1 - 0.34 10.7 10.2 0.088 12.6 2.7 2.4 2 0 0 2 2 2 0 Microtubule associated FlxA PF14282.1 ETO30170.1 - 0.44 10.5 9.3 1.3 9.0 6.4 1.7 1 1 0 1 1 1 0 FlxA-like protein Spc24 PF08286.6 ETO30170.1 - 0.57 9.8 10.9 0.38 10.4 5.0 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF342 PF03961.8 ETO30170.1 - 0.74 8.1 5.8 0.89 7.9 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) ADIP PF11559.3 ETO30170.1 - 1.5 8.6 7.7 11 5.9 5.3 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2680 PF10925.3 ETO30170.1 - 1.7 8.5 9.1 0.21 11.4 0.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2680) Vfa1 PF08432.5 ETO30170.1 - 2.1 8.3 11.8 2.8 7.9 8.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PGA2 PF07543.7 ETO30170.1 - 2.1 8.1 7.7 3.2 7.5 5.4 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 CDC37_N PF03234.9 ETO30170.1 - 2.9 8.1 10.0 5.7 7.2 7.0 1.5 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DUF3552 PF12072.3 ETO30170.1 - 3.3 6.8 11.8 4.4 6.4 8.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) CCDC-167 PF15188.1 ETO30170.1 - 3.5 7.6 11.4 2.3 8.2 2.9 2.4 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DivIVA PF05103.8 ETO30170.1 - 4.3 7.4 9.5 17 5.4 6.6 1.9 1 1 0 1 1 1 0 DivIVA protein Fib_alpha PF08702.5 ETO30170.1 - 6 6.9 7.5 3.7 7.6 3.3 1.9 2 1 0 2 2 1 0 Fibrinogen alpha/beta chain family Phage_GP20 PF06810.6 ETO30170.1 - 6 6.2 12.0 2 7.8 3.7 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 TMF_TATA_bd PF12325.3 ETO30170.1 - 6.4 6.5 11.0 15 5.3 3.3 2.3 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF972 PF06156.8 ETO30170.1 - 8.6 6.7 11.5 1.5 9.1 4.0 2.3 2 1 1 3 3 2 0 Protein of unknown function (DUF972) SAM_1 PF00536.25 ETO30171.1 - 3.2e-22 78.4 4.7 4.2e-11 42.8 0.3 2.8 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO30171.1 - 5.8e-21 74.1 2.7 3.6e-11 42.7 0.2 2.7 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) AAA_13 PF13166.1 ETO30171.1 - 0.83 8.0 58.6 0.0073 14.8 21.1 2.9 4 0 0 4 4 4 0 AAA domain Reo_sigmaC PF04582.7 ETO30171.1 - 2.1 7.4 17.1 19 4.3 8.5 3.2 2 1 0 2 2 2 0 Reovirus sigma C capsid protein FUSC PF04632.7 ETO30171.1 - 2.1 6.6 7.1 7.5 4.8 1.3 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF812 PF05667.6 ETO30171.1 - 4.5 5.6 43.4 0.29 9.5 18.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF812) DUF2051 PF09738.4 ETO30173.1 - 0.0024 17.2 9.0 0.098 11.9 6.3 2.1 1 1 1 2 2 2 1 Double stranded RNA binding protein (DUF2051) eIF-3c_N PF05470.7 ETO30173.1 - 0.013 13.6 4.0 0.014 13.5 2.8 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF1843 PF08898.5 ETO30173.1 - 0.053 13.5 7.5 0.85 9.7 2.6 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1843) Vpu PF00558.14 ETO30173.1 - 1.9 8.1 0.0 1.9 8.1 0.0 2.9 2 1 1 3 3 3 0 Vpu protein TMPIT PF07851.8 ETO30173.1 - 6.1 5.8 8.5 9 5.2 5.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF972 PF06156.8 ETO30173.1 - 8.2 6.8 16.0 23 5.3 11.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Sugar_tr PF00083.19 ETO30174.1 - 6.7e-05 21.6 10.6 8.7e-05 21.2 0.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter Herpes_UL43 PF05072.8 ETO30174.1 - 0.063 12.0 0.3 0.095 11.4 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus UL43 protein TctB PF07331.6 ETO30174.1 - 0.15 11.7 9.6 0.63 9.6 1.6 2.3 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family RRN3 PF05327.6 ETO30175.1 - 0.0017 16.5 0.2 0.0021 16.2 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 LMBR1 PF04791.11 ETO30175.1 - 0.019 13.5 1.6 0.023 13.2 1.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CDC45 PF02724.9 ETO30175.1 - 0.019 13.0 9.5 0.027 12.5 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Med12-LCEWAV PF12145.3 ETO30175.1 - 0.081 11.4 7.2 0.13 10.7 5.0 1.2 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain AUX_IAA PF02309.11 ETO30175.1 - 0.083 12.6 12.6 0.13 11.9 8.7 1.3 1 0 0 1 1 1 0 AUX/IAA family Neur_chan_memb PF02932.11 ETO30175.1 - 0.15 11.9 0.8 0.21 11.4 0.5 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region UPF0233 PF06781.7 ETO30175.1 - 0.17 11.5 0.8 0.63 9.7 0.6 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0233) Ctr PF04145.10 ETO30175.1 - 2.6 8.0 4.8 6.7 6.7 3.3 1.8 1 1 0 1 1 1 0 Ctr copper transporter family WD40 PF00400.27 ETO30176.1 - 6.3e-77 250.9 19.3 3.8e-13 48.7 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO30176.1 - 4.3e-13 48.2 4.4 0.015 13.4 0.1 5.6 2 1 3 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO30176.1 - 2.3e-07 29.9 13.7 0.12 11.1 0.1 5.9 1 1 3 4 4 4 3 Nup133 N terminal like PQQ_2 PF13360.1 ETO30176.1 - 3.9e-05 23.2 0.2 0.00034 20.1 0.0 2.3 2 1 0 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO30176.1 - 0.00066 18.0 1.6 0.23 9.7 0.0 2.9 1 1 3 4 4 4 2 Cytochrome D1 heme domain PD40 PF07676.7 ETO30176.1 - 0.73 9.5 3.5 1e+02 2.7 0.0 4.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 ETO30177.1 - 1.1e-70 231.2 12.3 6.1e-14 51.2 0.1 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 ETO30177.1 - 8.2e-10 38.7 0.1 0.018 14.7 0.0 3.5 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO30177.1 - 2.6e-09 35.7 1.3 0.046 11.8 0.1 4.1 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO30177.1 - 1.6e-05 23.3 1.3 0.24 9.6 0.1 3.0 1 1 2 3 3 3 3 Cytochrome D1 heme domain PD40 PF07676.7 ETO30177.1 - 5.9e-05 22.6 4.3 2.9 7.6 0.1 5.0 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat SGL PF08450.7 ETO30177.1 - 0.00062 19.2 0.1 0.0049 16.2 0.0 2.4 1 1 1 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Hira PF07569.6 ETO30177.1 - 0.0012 18.0 0.2 0.13 11.4 0.1 3.0 2 1 0 3 3 3 1 TUP1-like enhancer of split Str_synth PF03088.11 ETO30177.1 - 0.002 18.1 0.1 5 7.2 0.0 3.9 4 1 0 4 4 4 1 Strictosidine synthase Resistin PF06954.6 ETO30177.1 - 0.011 15.9 0.2 31 4.9 0.0 3.7 2 1 2 4 4 4 0 Resistin Biotin_lipoyl_2 PF13533.1 ETO30177.1 - 0.05 13.2 0.1 0.18 11.4 0.0 2.1 2 0 0 2 2 2 0 Biotin-lipoyl like Proteasome_A_N PF10584.4 ETO30177.1 - 0.11 11.8 0.0 20 4.5 0.0 2.8 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature FKBP_C PF00254.23 ETO30178.1 - 2.7e-23 81.8 1.0 1.2e-22 79.6 0.0 2.5 3 0 0 3 3 3 1 FKBP-type peptidyl-prolyl cis-trans isomerase zf-TRAF PF02176.13 ETO30178.1 - 5.8e-05 23.3 2.3 5.8e-05 23.3 1.6 2.7 2 1 0 2 2 2 1 TRAF-type zinc finger DDE_3 PF13358.1 ETO30178.1 - 0.0088 15.8 0.2 0.018 14.7 0.1 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-C3HC4_2 PF13923.1 ETO30178.1 - 0.78 9.8 7.6 0.12 12.3 0.7 3.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RNB PF00773.14 ETO30178.1 - 2.9 7.0 9.8 0.056 12.7 0.2 2.1 2 0 0 2 2 2 0 RNB domain FKBP_C PF00254.23 ETO30179.1 - 3.5e-26 91.0 0.4 8.9e-26 89.7 0.2 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase AvrE PF11725.3 ETO30179.1 - 1.7 5.5 19.2 2.1 5.2 13.3 1.0 1 0 0 1 1 1 0 Pathogenicity factor Alba PF01918.16 ETO30180.1 - 1.1e-12 47.3 0.1 1.9e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Alba Rpp20 PF12328.3 ETO30180.1 - 0.0018 17.9 0.1 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Eaf7 PF07904.8 ETO30180.1 - 0.081 12.9 0.1 0.25 11.3 0.0 1.8 1 1 0 1 1 1 0 Chromatin modification-related protein EAF7 CarD_CdnL_TRCF PF02559.11 ETO30180.1 - 0.13 12.3 0.1 0.26 11.3 0.1 1.5 1 0 0 1 1 1 0 CarD-like/TRCF domain DUF1985 PF09331.6 ETO30181.1 - 0.15 11.9 2.1 0.36 10.6 0.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1985) YodL PF14191.1 ETO30181.1 - 1.9 9.0 5.0 1.2 9.6 0.2 2.6 3 0 0 3 3 3 0 YodL-like Dynamin_M PF01031.15 ETO30184.1 - 2e-11 43.2 0.8 3.6e-11 42.3 0.5 1.3 1 0 0 1 1 1 1 Dynamin central region GED PF02212.13 ETO30184.1 - 1.2e-06 28.2 2.2 3e-06 27.0 1.5 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain Dynamin_N PF00350.18 ETO30185.1 - 7.8e-28 97.3 0.2 7.8e-28 97.3 0.1 2.6 3 0 0 3 3 3 1 Dynamin family Dynamin_M PF01031.15 ETO30185.1 - 2.2e-11 43.1 3.4 2.2e-11 43.1 2.3 2.2 2 1 1 3 3 3 1 Dynamin central region MMR_HSR1 PF01926.18 ETO30185.1 - 0.00025 20.9 2.8 0.00045 20.1 0.4 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 ETO30185.1 - 0.0014 18.1 0.8 0.15 11.5 0.3 3.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 ETO30185.1 - 0.009 16.5 3.2 0.0099 16.3 0.1 2.6 2 1 3 5 5 5 1 Miro-like protein YjcZ PF13990.1 ETO30185.1 - 0.014 14.4 1.4 0.019 14.1 0.3 1.6 2 0 0 2 2 2 0 YjcZ-like protein OAF PF14941.1 ETO30185.1 - 0.035 13.2 0.2 0.47 9.5 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator, Out at first AAA_16 PF13191.1 ETO30185.1 - 0.079 12.9 0.2 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 ETO30185.1 - 0.089 13.0 0.1 0.089 13.0 0.1 2.0 2 1 0 2 2 2 0 ABC transporter Peptidase_M75 PF09375.5 ETO30185.1 - 0.15 11.3 2.1 0.091 12.0 0.2 1.5 2 0 0 2 2 2 0 Imelysin AAA_21 PF13304.1 ETO30185.1 - 0.35 10.7 7.2 0.17 11.8 0.1 2.4 2 1 0 2 2 2 0 AAA domain DUF883 PF05957.8 ETO30185.1 - 2.4 8.6 5.2 9.5 6.6 0.0 3.1 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) OmpH PF03938.9 ETO30185.1 - 9.9 6.0 10.5 56 3.6 0.0 2.4 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) IMPDH PF00478.20 ETO30186.1 - 4.8e-113 377.6 1.6 6e-113 377.3 1.1 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain PcrB PF01884.12 ETO30186.1 - 0.0018 17.5 1.1 0.0064 15.7 0.0 2.0 2 0 0 2 2 2 1 PcrB family FMN_dh PF01070.13 ETO30186.1 - 0.026 13.3 2.3 0.052 12.3 1.0 1.7 1 1 0 2 2 2 0 FMN-dependent dehydrogenase Aldolase PF01081.14 ETO30186.1 - 0.036 13.2 0.8 0.31 10.1 0.0 2.2 1 1 1 2 2 2 0 KDPG and KHG aldolase Cobalamin_bind PF01122.14 ETO30187.1 - 0.033 12.8 0.1 0.037 12.6 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic cobalamin-binding protein ApoO PF09769.4 ETO30187.1 - 0.082 12.6 0.1 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Apolipoprotein O DUF3802 PF12290.3 ETO30188.1 - 0.012 15.9 0.1 0.026 14.8 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3802) Syntaxin-6_N PF09177.6 ETO30188.1 - 0.047 14.1 1.4 3.4 8.1 0.5 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF948 PF06103.6 ETO30188.1 - 0.094 12.5 1.1 1.3 8.9 0.0 2.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF2204 PF09970.4 ETO30188.1 - 0.096 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) RasGEF PF00617.14 ETO30189.1 - 3.7e-34 118.0 3.0 4.2e-27 95.0 1.5 2.5 2 0 0 2 2 2 2 RasGEF domain RasGEF_N PF00618.15 ETO30189.1 - 0.15 12.1 4.7 0.79 9.8 0.0 3.4 3 0 0 3 3 3 0 RasGEF N-terminal motif TPT PF03151.11 ETO30191.1 - 1.7e-06 27.7 2.7 2.4e-06 27.2 1.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EmrE PF13536.1 ETO30191.1 - 0.0083 16.3 1.9 0.011 15.9 1.3 1.1 1 0 0 1 1 1 1 Multidrug resistance efflux transporter HAP1_N PF04849.8 ETO30192.1 - 0.0008 18.4 6.5 0.0008 18.4 4.5 1.8 2 0 0 2 2 2 1 HAP1 N-terminal conserved region TSC22 PF01166.13 ETO30192.1 - 0.049 13.5 2.1 0.19 11.6 1.4 2.0 1 0 0 1 1 1 0 TSC-22/dip/bun family LMBR1 PF04791.11 ETO30192.1 - 0.18 10.3 3.9 0.23 9.9 2.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1428 PF07237.6 ETO30193.1 - 0.0013 18.6 0.2 0.0031 17.3 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1428) DUF572 PF04502.8 ETO30193.1 - 0.096 11.8 14.3 0.13 11.5 9.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Menin PF05053.8 ETO30193.1 - 1.4 6.9 11.1 1.6 6.8 7.7 1.1 1 0 0 1 1 1 0 Menin DUF2981 PF11200.3 ETO30193.1 - 1.8 7.5 15.0 1.2 8.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) AUX_IAA PF02309.11 ETO30193.1 - 7.8 6.1 10.6 4.4 6.9 6.2 1.5 1 1 0 1 1 1 0 AUX/IAA family SOBP PF15279.1 ETO30194.1 - 0.31 11.3 4.8 0.46 10.8 3.3 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DUF966 PF06136.8 ETO30194.1 - 0.39 10.0 14.1 0.5 9.7 9.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Peptidase_S64 PF08192.6 ETO30194.1 - 1.4 7.1 10.1 1.9 6.7 7.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 Daxx PF03344.10 ETO30194.1 - 4.2 5.7 27.8 0.26 9.7 12.5 2.1 2 0 0 2 2 2 0 Daxx Family MMR_HSR1 PF01926.18 ETO30197.1 - 5.4e-08 32.8 0.7 2.8e-07 30.5 0.2 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 ETO30197.1 - 7.9e-06 25.7 0.2 1.5e-05 24.8 0.2 1.5 1 1 0 1 1 1 1 Dynamin family Miro PF08477.8 ETO30197.1 - 0.0034 17.8 0.3 0.037 14.5 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein Terminase_1 PF03354.10 ETO30197.1 - 0.037 12.4 0.4 0.051 11.9 0.3 1.1 1 0 0 1 1 1 0 Phage Terminase FeoB_N PF02421.13 ETO30197.1 - 0.11 11.7 0.0 0.27 10.4 0.0 1.7 1 0 0 1 1 1 0 Ferrous iron transport protein B AIG1 PF04548.11 ETO30197.1 - 0.15 11.1 1.4 1.6 7.7 0.0 2.8 3 1 0 3 3 3 0 AIG1 family AAA_14 PF13173.1 ETO30197.1 - 0.33 10.8 2.6 6.6 6.6 0.1 3.1 1 1 0 2 2 2 0 AAA domain Lipoprotein_10 PF03202.8 ETO30198.1 - 4.2 7.3 8.8 7.2 6.6 4.0 1.9 1 1 1 2 2 2 0 Putative mycoplasma lipoprotein, C-terminal region Rota_VP2 PF05087.7 ETO30199.1 - 0.066 11.1 9.3 0.08 10.8 6.5 1.0 1 0 0 1 1 1 0 Rotavirus VP2 protein Presenilin PF01080.12 ETO30199.1 - 9.8 4.8 9.0 1.6 7.4 3.8 1.4 2 0 0 2 2 2 0 Presenilin DUF3439 PF11921.3 ETO30201.1 - 0.41 10.3 10.3 1.1 9.0 7.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) OTCace PF00185.19 ETO30204.1 - 0.075 12.9 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Ebola_NP PF05505.7 ETO30204.1 - 3.1 5.7 10.3 4 5.3 7.1 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein DUF2201_N PF13203.1 ETO30204.1 - 7.8 5.5 8.7 11 5.0 6.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain NUDIX PF00293.23 ETO30205.1 - 1.7e-12 47.1 0.0 2.1e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain PDEase_I PF00233.14 ETO30206.1 - 3.1e-19 69.6 0.0 7.1e-17 61.9 0.0 2.2 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Mucin PF01456.12 ETO30206.1 - 0.025 14.3 0.1 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Macoilin PF09726.4 ETO30206.1 - 4.7 5.3 11.9 5.7 5.0 8.3 1.1 1 0 0 1 1 1 0 Transmembrane protein PDEase_I PF00233.14 ETO30207.1 - 3e-23 82.7 6.1 1.9e-22 80.1 4.2 2.0 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF2624 PF11116.3 ETO30208.1 - 0.076 13.5 0.1 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) RPN7 PF10602.4 ETO30209.1 - 2.4e-34 118.2 4.3 4.7e-34 117.3 3.0 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 ETO30209.1 - 1.7e-17 63.6 2.2 2e-17 63.4 0.4 1.9 1 1 1 2 2 2 1 PCI domain WD-3 PF09765.4 ETO30209.1 - 0.017 14.3 1.5 0.04 13.1 1.0 1.6 1 1 0 1 1 1 0 WD-repeat region Mito_carr PF00153.22 ETO30210.1 - 5.5e-20 70.8 2.4 2.2e-15 56.0 0.0 3.5 2 1 1 3 3 3 2 Mitochondrial carrier protein ATP-synt_ab_N PF02874.18 ETO30212.1 - 2.4e-05 24.4 0.0 5.7e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain HAT PF02184.11 ETO30213.1 - 1.6e-09 37.3 20.0 0.0033 17.1 0.0 6.6 6 1 0 6 6 6 3 HAT (Half-A-TPR) repeat Suf PF05843.9 ETO30213.1 - 2e-07 31.0 6.7 0.0019 18.0 1.4 2.5 1 1 1 2 2 2 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 ETO30213.1 - 4.5e-05 23.7 0.0 4.3 8.2 0.0 4.5 3 1 2 5 5 5 1 Tetratricopeptide repeat MRP-S31 PF15433.1 ETO30213.1 - 0.013 14.9 0.5 0.12 11.7 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 ATP-synt PF00231.14 ETO30213.1 - 0.027 13.8 0.5 0.066 12.5 0.4 1.7 1 1 0 1 1 1 0 ATP synthase Apc3 PF12895.2 ETO30213.1 - 0.03 14.4 3.2 0.33 11.0 0.5 2.8 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO30213.1 - 0.084 13.2 0.0 6.7 7.1 0.0 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETO30213.1 - 0.16 11.8 1.5 43 4.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat HAT PF02184.11 ETO30214.1 - 4.2e-14 51.9 26.2 0.00025 20.7 0.1 6.5 7 0 0 7 7 7 4 HAT (Half-A-TPR) repeat TPR_16 PF13432.1 ETO30214.1 - 1.4e-06 28.7 1.9 0.88 10.3 0.0 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO30214.1 - 4.9e-05 23.5 3.8 0.58 10.9 0.1 5.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO30214.1 - 0.0042 17.3 0.1 20 5.5 0.0 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat U3_assoc_6 PF08640.6 ETO30214.1 - 0.0056 16.3 16.5 0.24 11.1 0.2 4.5 3 3 1 4 4 4 2 U3 small nucleolar RNA-associated protein 6 Suf PF05843.9 ETO30214.1 - 0.0083 15.8 2.0 0.0083 15.8 1.4 3.5 2 2 1 3 3 3 1 Suppressor of forked protein (Suf) TPR_6 PF13174.1 ETO30214.1 - 0.91 10.1 5.7 33 5.2 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 ETO30214.1 - 2.3 8.6 5.0 7.8 6.9 0.3 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.20 ETO30215.1 - 8.1e-11 41.5 1.2 1.6e-10 40.6 0.8 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 ETO30216.1 - 3.4e-09 36.2 0.0 1.3e-07 31.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain DUF2628 PF10947.3 ETO30216.1 - 0.052 13.3 0.4 0.052 13.3 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) DUF2207 PF09972.4 ETO30216.1 - 6.6 5.1 8.6 6 5.3 0.5 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF3723 PF12520.3 ETO30217.1 - 0.012 14.1 0.6 0.02 13.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3723) HD_assoc PF13286.1 ETO30217.1 - 0.093 13.0 0.5 0.19 11.9 0.2 1.7 1 1 0 1 1 1 0 Phosphohydrolase-associated domain Fis1_TPR_C PF14853.1 ETO30218.1 - 0.00044 20.0 0.8 0.0038 17.0 0.1 2.4 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.12 ETO30218.1 - 0.0012 18.6 4.9 0.0029 17.4 0.1 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETO30218.1 - 0.0022 17.8 0.1 0.014 15.2 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO30218.1 - 0.003 17.0 0.6 0.011 15.3 0.4 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO30218.1 - 0.0066 16.8 1.0 0.36 11.3 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO30218.1 - 0.014 15.2 0.7 0.037 13.9 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 ETO30218.1 - 0.078 12.6 3.2 0.69 9.6 0.8 3.0 3 1 0 3 3 3 0 TPR repeat TPR_8 PF13181.1 ETO30218.1 - 0.49 10.2 3.6 0.38 10.6 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DELLA PF12041.3 ETO30219.1 - 0.077 12.6 0.3 0.22 11.2 0.2 1.7 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal Myotub-related PF06602.9 ETO30220.1 - 6.4e-39 133.7 0.5 7.9e-39 133.4 0.3 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Myotub-related PF06602.9 ETO30221.1 - 1.2e-69 234.7 1.1 2.5e-69 233.7 0.8 1.4 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 ETO30221.1 - 0.0069 16.6 0.9 0.024 14.9 0.0 2.3 2 1 0 2 2 2 1 Tyrosine phosphatase family Menin PF05053.8 ETO30221.1 - 0.019 13.1 13.8 0.39 8.8 0.3 2.1 2 0 0 2 2 2 0 Menin FtsL PF04999.8 ETO30221.1 - 0.37 10.5 7.7 0.19 11.4 1.5 2.6 2 0 0 2 2 2 0 Cell division protein FtsL Ion_trans PF00520.26 ETO30221.1 - 8.2 5.6 8.8 0.65 9.2 0.2 2.5 3 0 0 3 3 3 0 Ion transport protein C1_3 PF07649.7 ETO30222.1 - 1.7e-05 24.7 3.9 1.7e-05 24.7 2.7 2.2 3 0 0 3 3 3 1 C1-like domain ZZ PF00569.12 ETO30222.1 - 0.00025 20.5 6.3 0.00063 19.2 4.4 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.11 ETO30222.1 - 0.00046 20.2 10.9 0.00046 20.2 7.6 2.0 2 0 0 2 2 2 1 C1 domain ABC_membrane_2 PF06472.10 ETO30222.1 - 0.0035 16.4 0.3 0.0035 16.4 0.2 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 C1_1 PF00130.17 ETO30222.1 - 2.4 7.9 14.1 0.035 13.8 4.2 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_4 PF14570.1 ETO30222.1 - 5 6.7 15.0 0.044 13.3 4.2 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF2013 PF09431.5 ETO30223.1 - 0.055 13.2 0.3 0.14 11.8 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2013) Flu_PB2 PF00604.12 ETO30223.1 - 0.056 11.3 0.1 0.062 11.1 0.0 1.0 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB2 HEAT_2 PF13646.1 ETO30223.1 - 0.085 13.1 0.0 7.4 6.9 0.0 2.0 1 1 1 2 2 2 0 HEAT repeats DMP1 PF07263.6 ETO30224.1 - 0.017 13.8 1.8 0.017 13.8 1.2 2.1 2 0 0 2 2 2 0 Dentin matrix protein 1 (DMP1) Herpes_DNAp_acc PF04929.7 ETO30224.1 - 0.19 10.6 8.6 0.27 10.1 6.0 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor GPCR_chapero_1 PF11904.3 ETO30224.1 - 0.29 10.2 10.0 0.4 9.7 6.9 1.1 1 0 0 1 1 1 0 GPCR-chaperone DNA_pol_viral_N PF00242.12 ETO30224.1 - 0.55 9.2 12.5 0.63 9.0 8.7 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF4048 PF13257.1 ETO30224.1 - 0.68 9.5 18.8 1 8.9 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4048) Apt1 PF10351.4 ETO30224.1 - 1.8 7.3 16.0 2.3 6.9 11.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ndc1_Nup PF09531.5 ETO30224.1 - 7.7 4.8 9.1 8.2 4.7 6.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Secretin_N_2 PF07655.8 ETO30224.1 - 9.1 6.7 14.5 6.6 7.2 6.9 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain YqfQ PF14181.1 ETO30224.1 - 9.3 6.2 18.0 6 6.8 8.1 2.1 2 0 0 2 2 2 0 YqfQ-like protein Glyco_transf_49 PF13896.1 ETO30225.1 - 7.3e-34 117.2 6.2 1.7e-33 116.1 4.3 1.6 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 ETO30225.1 - 4.6e-06 25.9 2.2 6e-06 25.5 0.1 2.1 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Borrelia_orfX PF04160.7 ETO30225.1 - 0.17 11.6 2.8 1 9.1 0.8 2.1 2 0 0 2 2 2 0 Orf-X protein zf-C2H2_jaz PF12171.3 ETO30228.1 - 1.7e-05 24.7 7.9 0.028 14.5 0.1 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 ETO30228.1 - 3.3e-05 23.9 9.4 0.0046 17.2 0.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.2 ETO30228.1 - 0.0004 20.4 7.5 0.053 13.7 1.5 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 ETO30228.1 - 0.0027 17.9 8.3 0.37 11.2 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETO30228.1 - 0.0056 16.9 7.6 0.13 12.6 1.3 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 ETO30228.1 - 0.018 14.9 6.5 0.28 11.1 0.9 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger C1_4 PF07975.7 ETO30228.1 - 0.019 14.9 3.7 0.019 14.9 2.5 2.2 2 2 0 2 2 2 0 TFIIH C1-like domain zf-4CXXC_R1 PF10497.4 ETO30228.1 - 0.052 13.6 5.8 0.039 14.0 3.3 1.4 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Ribosomal_L37ae PF01780.14 ETO30228.1 - 0.13 12.1 8.0 1.9 8.4 5.0 2.2 1 1 1 2 2 2 0 Ribosomal L37ae protein family RIG-I_C-RD PF11648.3 ETO30228.1 - 0.76 9.6 10.2 0.5 10.2 5.7 1.7 1 1 1 2 2 2 0 C-terminal domain of RIG-I Yippee-Mis18 PF03226.9 ETO30228.1 - 3.1 7.8 8.1 2.6 8.1 0.3 2.3 1 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Elf1 PF05129.8 ETO30228.1 - 4.8 6.9 16.6 0.081 12.6 4.9 2.6 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Fer4_9 PF13187.1 ETO30228.1 - 5.5 7.3 6.6 0.87 9.9 1.2 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain Zn_Tnp_IS1595 PF12760.2 ETO30228.1 - 7.5 6.4 8.3 31 4.4 5.8 2.1 1 1 0 1 1 1 0 Transposase zinc-ribbon domain SNF2_N PF00176.18 ETO30229.1 - 3.9e-31 107.9 0.1 1.6e-30 105.9 0.1 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 ETO30229.1 - 6.7e-10 39.1 0.0 6.7e-10 39.1 0.0 2.7 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Occludin_ELL PF07303.8 ETO30230.1 - 0.0013 19.3 4.1 0.088 13.5 0.5 2.6 2 1 1 3 3 3 2 Occludin homology domain GvpL_GvpF PF06386.6 ETO30230.1 - 0.089 12.3 0.3 0.16 11.5 0.2 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF342 PF03961.8 ETO30230.1 - 0.11 10.8 1.4 0.13 10.6 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) RasGEF_N_2 PF14663.1 ETO30231.1 - 3.4e-15 55.9 0.2 1.5e-14 53.8 0.1 2.3 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 ETO30231.1 - 1.1e-14 54.1 1.3 2.4e-12 46.6 0.1 4.6 5 1 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 RICTOR_M PF14666.1 ETO30231.1 - 1.8e-12 46.8 5.8 2.8e-12 46.1 0.1 3.4 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain DUF3753 PF12575.3 ETO30231.1 - 0.065 13.0 0.2 0.31 10.8 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) CAP_GLY PF01302.20 ETO30233.1 - 4.3e-38 128.8 18.1 7.8e-16 57.5 0.2 4.5 5 0 0 5 5 5 3 CAP-Gly domain YajC PF02699.10 ETO30233.1 - 0.001 18.6 5.2 0.022 14.3 0.2 3.4 3 0 0 3 3 3 1 Preprotein translocase subunit CAP_GLY PF01302.20 ETO30234.1 - 2e-34 117.0 13.1 2.6e-12 46.2 0.1 4.3 4 0 0 4 4 4 4 CAP-Gly domain CAP_GLY PF01302.20 ETO30235.1 - 1.1e-27 95.5 5.7 1.2e-09 37.7 0.1 3.4 3 0 0 3 3 3 3 CAP-Gly domain SspB PF04386.8 ETO30235.1 - 0.045 13.3 1.7 0.088 12.4 1.2 1.4 1 0 0 1 1 1 0 Stringent starvation protein B YajC PF02699.10 ETO30235.1 - 0.062 12.9 11.0 2.5 7.8 0.0 4.5 5 0 0 5 5 5 0 Preprotein translocase subunit CAP_GLY PF01302.20 ETO30236.1 - 1.5e-132 431.4 54.4 3e-15 55.6 0.2 11.2 11 0 0 11 11 11 11 CAP-Gly domain RseC_MucC PF04246.7 ETO30236.1 - 0.49 9.9 0.4 62 3.1 0.0 3.8 5 0 0 5 5 5 0 Positive regulator of sigma(E), RseC/MucC YajC PF02699.10 ETO30236.1 - 0.65 9.7 16.8 16 5.2 0.2 7.2 8 0 0 8 8 8 0 Preprotein translocase subunit Pkinase PF00069.20 ETO30237.1 - 9.2e-28 97.0 6.8 3.5e-27 95.1 4.6 2.1 1 1 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 ETO30237.1 - 1.5 8.3 9.8 0.017 14.6 0.7 2.4 2 1 0 2 2 2 0 Choline/ethanolamine kinase ERM PF00769.14 ETO30238.1 - 0.3 10.5 33.3 0.5 9.8 23.1 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.4 ETO30238.1 - 0.31 10.9 37.0 0.019 14.8 13.4 2.3 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0118 PF01594.11 ETO30238.1 - 4.1 6.2 10.5 0.23 10.4 0.9 2.3 1 1 1 2 2 2 0 Domain of unknown function DUF20 DUF972 PF06156.8 ETO30238.1 - 4.4 7.6 29.3 0.098 13.0 7.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) O-antigen_lig PF13425.1 ETO30240.1 - 0.93 9.4 6.1 1.4 8.8 4.2 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein TGS PF02824.16 ETO30241.1 - 1.2e-10 41.0 0.0 2e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 TGS domain SM-ATX PF14438.1 ETO30241.1 - 0.058 13.3 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain RRXRR PF14239.1 ETO30241.1 - 0.092 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 RRXRR protein DSPc PF00782.15 ETO30242.1 - 9.4e-10 38.1 0.1 2.9e-09 36.5 0.1 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTR2 PF00854.16 ETO30243.1 - 0.058 12.1 0.4 0.081 11.6 0.3 1.1 1 0 0 1 1 1 0 POT family Kelch_4 PF13418.1 ETO30245.1 - 2e-05 24.2 0.1 0.066 12.9 0.0 3.7 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO30245.1 - 6.5e-05 22.3 1.1 0.44 10.1 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO30245.1 - 0.00012 22.1 5.9 0.8 9.9 0.0 5.1 4 1 1 5 5 5 1 Kelch motif Kelch_2 PF07646.10 ETO30245.1 - 0.00052 19.6 2.7 5.9 6.8 0.0 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 ETO30245.1 - 0.0042 16.9 0.7 0.15 12.0 0.1 3.3 3 0 0 3 3 3 1 Kelch motif DDOST_48kD PF03345.9 ETO30249.1 - 7.7e-22 77.4 0.7 1.7e-18 66.3 0.7 2.2 1 1 1 2 2 2 2 Oligosaccharyltransferase 48 kDa subunit beta MAPEG PF01124.13 ETO30250.1 - 1e-05 25.1 0.2 1.4e-05 24.6 0.2 1.1 1 0 0 1 1 1 1 MAPEG family DUF1625 PF07787.7 ETO30251.1 - 0.037 13.2 0.2 0.038 13.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) SR-25 PF10500.4 ETO30252.1 - 1.7 8.0 11.9 4.9 6.5 0.1 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF1802 PF08819.6 ETO30253.1 - 0.0075 15.8 0.4 0.011 15.3 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1802) U3_snoRNA_assoc PF08297.6 ETO30253.1 - 0.032 14.4 0.0 0.11 12.7 0.0 1.9 2 1 0 2 2 2 0 U3 snoRNA associated eIF-3_zeta PF05091.7 ETO30254.1 - 8.8e-30 103.8 0.2 9.7e-29 100.3 0.1 1.9 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) INCENP_ARK-bind PF03941.10 ETO30255.1 - 2.8e-07 30.2 0.1 5.1e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region DrrA_P4M PF14860.1 ETO30255.1 - 0.0033 17.1 1.0 0.016 14.9 0.5 1.8 2 0 0 2 2 2 1 DrrA phosphatidylinositol 4-phosphate binding domain DUF1693 PF07984.7 ETO30255.1 - 0.11 11.6 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1693) NAD_Gly3P_dh_N PF01210.18 ETO30256.1 - 0.064 12.9 0.9 6.8 6.4 0.0 2.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus RXT2_N PF08595.6 ETO30257.1 - 0.21 11.3 5.4 0.094 12.5 2.2 1.6 2 0 0 2 2 2 0 RXT2-like, N-terminal PBP1_TM PF14812.1 ETO30257.1 - 1.1 9.6 3.1 26 5.2 2.3 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PUF PF00806.14 ETO30258.1 - 3.1e-39 130.2 15.3 1.1e-05 24.6 0.0 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat LRR_4 PF12799.2 ETO30259.1 - 0.0075 15.8 6.9 0.0075 15.8 4.8 12.4 6 3 7 14 14 14 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETO30259.1 - 2.7 8.3 113.9 0.36 11.0 0.2 16.5 16 3 1 17 17 17 0 Leucine Rich Repeat Zip PF02535.17 ETO30261.1 - 1.6e-12 47.0 10.3 1.6e-12 47.0 7.2 2.6 1 1 1 2 2 2 1 ZIP Zinc transporter Herpes_pp38 PF04846.8 ETO30261.1 - 0.73 9.1 4.8 0.58 9.5 1.8 2.0 2 0 0 2 2 2 0 Herpesvirus pp38 phosphoprotein EamA PF00892.15 ETO30261.1 - 4.1 7.4 17.7 0.079 12.9 2.3 3.6 1 1 2 3 3 3 0 EamA-like transporter family TPR_14 PF13428.1 ETO30264.1 - 0.048 14.3 0.0 14 6.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Uds1 PF15456.1 ETO30264.1 - 0.17 11.9 1.8 0.41 10.6 0.3 2.1 2 0 0 2 2 2 0 Up-regulated During Septation DUF1985 PF09331.6 ETO30266.1 - 0.025 14.3 0.2 0.045 13.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1985) DUF1057 PF06342.7 ETO30266.1 - 0.039 12.7 0.1 0.048 12.4 0.1 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Pex14_N PF04695.8 ETO30266.1 - 2.6 8.1 8.3 1e+02 2.9 6.4 2.6 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PH_5 PF15405.1 ETO30267.1 - 2.7 7.9 6.2 0.26 11.2 0.3 2.2 2 1 0 2 2 2 0 Pleckstrin homology domain SPT6_acidic PF14632.1 ETO30267.1 - 8.9 6.5 10.4 2.1 8.5 0.1 2.8 2 1 0 2 2 2 0 Acidic N-terminal SPT6 Tannase PF07519.6 ETO30268.1 - 0.0081 14.9 0.1 0.011 14.4 0.1 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase GldM_N PF12081.3 ETO30268.1 - 0.083 12.4 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 GldM N-terminal domain PT PF04886.7 ETO30268.1 - 0.23 10.8 7.8 0.51 9.7 5.4 1.5 1 0 0 1 1 1 0 PT repeat DBD_Tnp_Hermes PF10683.4 ETO30269.1 - 0.022 14.2 0.0 1.5 8.3 0.0 2.5 2 0 0 2 2 2 0 Hermes transposase DNA-binding domain CDK2AP PF09806.4 ETO30272.1 - 0.081 13.1 0.8 0.14 12.4 0.5 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein zf-TRAF PF02176.13 ETO30273.1 - 3.6e-05 24.0 4.1 3.6e-05 24.0 2.9 2.8 2 0 0 2 2 2 1 TRAF-type zinc finger V_ATPase_I PF01496.14 ETO30273.1 - 1.7 6.4 6.3 2.4 5.8 4.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Carn_acyltransf PF00755.15 ETO30274.1 - 0.012 13.7 1.0 0.015 13.4 0.7 1.2 1 0 0 1 1 1 0 Choline/Carnitine o-acyltransferase DUF1796 PF08795.5 ETO30274.1 - 0.013 15.1 1.0 0.016 14.8 0.7 1.1 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) DUF1660 PF07874.6 ETO30274.1 - 0.16 12.2 1.4 0.31 11.3 1.0 1.6 1 0 0 1 1 1 0 Prophage protein (DUF1660) Toxin_52 PF15605.1 ETO30275.1 - 0.13 12.2 0.1 0.31 10.9 0.0 1.6 1 1 0 1 1 1 0 Putative toxin 52 Glyco_hydro_18 PF00704.23 ETO30276.1 - 1.4e-05 24.6 0.0 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Kp4 PF09044.5 ETO30276.1 - 0.026 14.3 0.2 0.05 13.4 0.1 1.5 1 0 0 1 1 1 0 Kp4 Baculo_DNA_bind PF04786.7 ETO30278.1 - 0.082 12.0 0.5 0.099 11.7 0.3 1.1 1 0 0 1 1 1 0 ssDNA binding protein UCH PF00443.24 ETO30280.1 - 8.7e-21 74.2 0.3 8.7e-21 74.2 0.2 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO30280.1 - 2e-08 34.0 2.3 2.9e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase AIG1 PF04548.11 ETO30281.1 - 4.5e-13 48.8 0.0 4.5e-13 48.8 0.0 2.3 2 1 1 3 3 3 1 AIG1 family MMR_HSR1 PF01926.18 ETO30281.1 - 0.00088 19.2 0.0 0.0022 17.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase SpoU_methylase PF00588.14 ETO30283.1 - 1.7e-25 89.5 0.0 2e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family SPOUT_MTase_2 PF14419.1 ETO30283.1 - 0.033 13.3 0.0 0.059 12.5 0.0 1.5 1 1 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP AIG1 PF04548.11 ETO30285.1 - 1.5e-18 66.6 0.0 1.5e-18 66.6 0.0 2.2 2 1 1 3 3 3 1 AIG1 family MMR_HSR1 PF01926.18 ETO30285.1 - 3.6e-07 30.1 0.2 1.4e-06 28.2 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 ETO30285.1 - 0.0001 21.5 0.5 0.0025 17.0 0.1 2.8 2 1 1 3 3 3 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 ETO30285.1 - 0.042 13.2 0.0 0.042 13.2 0.0 3.0 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain Mg_chelatase PF01078.16 ETO30285.1 - 0.07 12.2 0.1 1.6 7.8 0.0 2.6 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Pyr_redox_2 PF07992.9 ETO30285.1 - 0.34 10.7 2.2 0.74 9.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_S46 PF10459.4 ETO30285.1 - 0.49 8.7 17.2 0.81 8.0 11.9 1.3 1 0 0 1 1 1 0 Peptidase S46 Spc97_Spc98 PF04130.8 ETO30286.1 - 2.5e-54 184.5 3.3 3e-54 184.2 2.3 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Amidinotransf PF02274.12 ETO30287.1 - 1.7e-12 47.0 0.0 8.8e-08 31.5 0.0 2.2 2 0 0 2 2 2 2 Amidinotransferase Daxx PF03344.10 ETO30288.1 - 2.4e-05 23.0 51.2 3.1e-05 22.7 35.5 1.1 1 0 0 1 1 1 1 Daxx Family TFIIF_alpha PF05793.7 ETO30288.1 - 0.037 12.4 59.8 0.054 11.8 41.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MIP-T3 PF10243.4 ETO30288.1 - 0.26 9.7 46.4 0.36 9.2 32.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Menin PF05053.8 ETO30288.1 - 1.2 7.2 21.7 1.5 6.9 15.0 1.1 1 0 0 1 1 1 0 Menin CDC45 PF02724.9 ETO30289.1 - 1.4e-07 30.0 12.7 1.6e-07 29.7 8.8 1.0 1 0 0 1 1 1 1 CDC45-like protein Nucleo_P87 PF07267.6 ETO30289.1 - 0.14 10.7 7.1 0.19 10.4 4.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SDA1 PF05285.7 ETO30289.1 - 0.58 9.3 14.8 0.63 9.2 10.3 1.1 1 0 0 1 1 1 0 SDA1 BSMAP PF12280.3 ETO30289.1 - 4.2 7.1 6.8 1.2 9.0 1.3 1.9 1 1 1 2 2 2 0 Brain specific membrane anchored protein CDC45 PF02724.9 ETO30290.1 - 7.2e-48 163.0 0.2 9.3e-48 162.6 0.1 1.0 1 0 0 1 1 1 1 CDC45-like protein GMC_oxred_C PF05199.8 ETO30291.1 - 3.5e-28 98.7 0.3 3.9e-27 95.2 0.2 2.0 1 1 0 1 1 1 1 GMC oxidoreductase AA_permease PF00324.16 ETO30292.1 - 6.4e-41 140.1 32.5 1.7e-40 138.7 22.5 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETO30292.1 - 3.1e-18 65.5 31.4 4e-18 65.1 21.8 1.1 1 0 0 1 1 1 1 Amino acid permease TrkA_N PF02254.13 ETO30293.1 - 0.013 15.4 1.7 0.013 15.4 1.2 2.2 2 0 0 2 2 2 0 TrkA-N domain DUF3683 PF12447.3 ETO30293.1 - 1.2 9.0 8.1 0.22 11.3 1.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3683) HSP20 PF00011.16 ETO30294.1 - 1.3e-13 50.6 0.1 1.3e-13 50.6 0.1 2.4 2 1 0 2 2 2 1 Hsp20/alpha crystallin family SRP19 PF01922.12 ETO30294.1 - 0.088 13.3 4.9 0.22 12.1 3.4 1.7 1 1 0 1 1 1 0 SRP19 protein Consortin_C PF15281.1 ETO30294.1 - 0.33 10.4 0.1 0.33 10.4 0.1 3.0 1 1 2 3 3 3 0 Consortin C-terminus COX15-CtaA PF02628.10 ETO30295.1 - 0.36 9.6 0.0 0.54 9.0 0.0 1.2 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein M-inducer_phosp PF06617.8 ETO30296.1 - 0.011 14.8 0.1 0.021 13.9 0.1 1.4 1 0 0 1 1 1 0 M-phase inducer phosphatase Dev_Cell_Death PF10539.4 ETO30298.1 - 2.5e-14 52.9 0.0 7e-14 51.5 0.0 1.8 1 0 0 1 1 1 1 Development and cell death domain Flp_N PF03930.9 ETO30299.1 - 0.0041 16.8 0.3 0.01 15.5 0.2 1.6 1 0 0 1 1 1 1 Recombinase Flp protein N-terminus Novirhabdo_Nv PF05554.6 ETO30301.1 - 0.093 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Viral hemorrhagic septicemia virus non-virion protein FHIPEP PF00771.15 ETO30302.1 - 0.15 10.3 0.0 0.15 10.3 0.0 3.0 2 1 0 2 2 2 0 FHIPEP family EMP70 PF02990.11 ETO30303.1 - 1.1e-57 195.6 24.4 1.4e-57 195.3 16.9 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 DUF3309 PF11752.3 ETO30303.1 - 2.6 7.8 12.2 0.33 10.7 2.4 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3309) Cortexin PF11057.3 ETO30303.1 - 3.6 7.2 5.8 1.4 8.5 0.6 2.3 2 0 0 2 2 2 0 Cortexin of kidney PMSR PF01625.16 ETO30304.1 - 7.8e-38 129.8 6.3 2.3e-34 118.5 4.4 2.9 1 1 0 1 1 1 1 Peptide methionine sulfoxide reductase CENP-F_N PF10481.4 ETO30304.1 - 0.022 14.1 0.7 0.033 13.5 0.5 1.2 1 0 0 1 1 1 0 Cenp-F N-terminal domain Mob1_phocein PF03637.12 ETO30305.1 - 2.5e-33 115.1 13.3 6.2e-32 110.6 9.2 2.1 1 1 0 1 1 1 1 Mob1/phocein family NSs PF11073.3 ETO30305.1 - 0.021 14.0 0.1 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Rift valley fever virus non structural protein (NSs) like Ank PF00023.25 ETO30306.1 - 2.7e-33 112.1 2.2 5.1e-07 29.1 0.2 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 ETO30306.1 - 8.2e-32 109.4 0.4 1.1e-18 67.3 0.7 2.8 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO30306.1 - 1.7e-21 76.1 0.7 3.4e-07 30.5 0.0 4.6 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO30306.1 - 2.9e-20 70.3 3.3 0.0011 19.0 0.0 6.0 5 1 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 ETO30306.1 - 4.3e-19 68.1 1.2 2.1e-05 24.5 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) SH3_1 PF00018.23 ETO30306.1 - 0.081 12.3 0.0 0.24 10.8 0.0 1.8 1 0 0 1 1 1 0 SH3 domain Mito_carr PF00153.22 ETO30307.1 - 7.9e-40 134.4 0.7 2.6e-19 68.6 0.2 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein PP2C PF00481.16 ETO30309.1 - 3.5e-40 138.0 0.2 4.9e-29 101.4 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 ETO30309.1 - 8e-06 25.6 0.0 0.022 14.4 0.0 2.4 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 ETO30309.1 - 0.00072 19.0 0.0 0.0019 17.6 0.0 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C Metallophos PF00149.23 ETO30311.1 - 3.8e-08 32.9 3.1 5e-08 32.5 1.9 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 ETO30311.1 - 0.00016 21.6 0.7 0.00044 20.2 0.5 1.7 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C SDA1 PF05285.7 ETO30312.1 - 0.023 13.9 26.1 0.18 11.0 5.0 2.3 2 0 0 2 2 2 0 SDA1 CDC45 PF02724.9 ETO30312.1 - 0.98 7.3 23.2 0.18 9.8 4.1 2.2 2 0 0 2 2 2 0 CDC45-like protein Daxx PF03344.10 ETO30312.1 - 3.1 6.1 28.8 0.41 9.0 5.2 2.2 2 0 0 2 2 2 0 Daxx Family Mem_trans PF03547.13 ETO30312.1 - 8.8 4.5 14.8 0.14 10.4 1.4 2.1 2 0 0 2 2 2 0 Membrane transport protein Sporozoite_P67 PF05642.6 ETO30313.1 - 0.0093 13.8 11.6 0.014 13.2 8.0 1.3 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Abhydrolase_2 PF02230.11 ETO30314.1 - 1.4e-06 27.9 0.0 2.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 ETO30314.1 - 0.024 14.4 0.0 0.032 13.9 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.15 ETO30314.1 - 0.086 12.2 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Putative esterase Na_trans_assoc PF06512.8 ETO30315.1 - 0.015 15.3 5.7 0.021 14.8 3.9 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated DUF2413 PF10310.4 ETO30315.1 - 0.035 12.9 8.2 0.044 12.6 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF3484 PF11983.3 ETO30317.1 - 0.13 13.0 5.0 0.62 10.9 0.2 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3484) Pkinase PF00069.20 ETO30318.1 - 2.3e-07 30.2 0.0 2.5e-07 30.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO30318.1 - 0.019 14.0 0.0 0.019 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase ABC1 PF03109.11 ETO30318.1 - 0.037 14.0 0.0 0.05 13.5 0.0 1.2 1 0 0 1 1 1 0 ABC1 family adh_short PF00106.20 ETO30319.1 - 1.7e-16 60.6 0.0 2.1e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETO30319.1 - 3e-11 43.3 0.0 3.7e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 ETO30319.1 - 8.3e-07 28.1 1.8 1.2e-06 27.6 1.3 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 ETO30319.1 - 4.9e-06 26.4 0.6 7.1e-06 25.9 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.7 ETO30319.1 - 0.0023 16.8 0.1 0.0046 15.9 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 ETO30319.1 - 0.0048 15.6 0.3 0.0063 15.2 0.2 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family EF-hand_7 PF13499.1 ETO30319.1 - 0.015 15.3 0.5 0.028 14.5 0.3 1.5 1 1 0 1 1 1 0 EF-hand domain pair Shikimate_DH PF01488.15 ETO30319.1 - 0.047 13.7 1.6 0.092 12.8 1.1 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_5 PF07994.7 ETO30319.1 - 0.1 12.0 1.3 0.12 11.8 0.9 1.1 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase NAD_binding_10 PF13460.1 ETO30319.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding DUF3574 PF12098.3 ETO30319.1 - 0.98 9.0 3.1 18 5.0 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3574) Acetyltransf_3 PF13302.1 ETO30320.1 - 4.9e-12 46.2 0.0 5.6e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 ETO30320.1 - 2.5e-08 34.0 0.2 3e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETO30320.1 - 5.5e-07 29.5 0.0 6.9e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 ETO30320.1 - 4.2e-05 23.2 0.0 5.8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 ETO30320.1 - 0.00011 22.1 0.0 0.00012 21.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HMG_box PF00505.14 ETO30321.1 - 0.0051 17.0 0.8 0.0084 16.3 0.5 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box CCT PF06203.9 ETO30321.1 - 0.06 12.9 0.1 0.06 12.9 0.0 2.0 3 0 0 3 3 3 0 CCT motif U1snRNP70_N PF12220.3 ETO30321.1 - 0.49 10.7 5.5 0.8 10.0 3.8 1.6 1 1 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Repressor_Mnt PF11423.3 ETO30322.1 - 0.12 11.6 0.9 1.7 8.0 0.1 2.9 3 0 0 3 3 3 0 Regulatory protein Mnt DUF2457 PF10446.4 ETO30322.1 - 0.5 9.0 6.6 0.62 8.7 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF4611 PF15387.1 ETO30322.1 - 2.1 8.5 6.6 1.1e+02 3.0 5.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Kelch_2 PF07646.10 ETO30323.1 - 6.3e-08 32.0 1.6 0.035 13.8 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 ETO30323.1 - 3.5e-06 26.9 0.7 0.055 13.6 0.0 3.9 3 1 1 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO30323.1 - 0.0001 21.9 0.0 0.003 17.2 0.0 2.9 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO30323.1 - 0.004 17.0 2.5 5 7.1 0.0 4.7 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.20 ETO30323.1 - 0.044 13.3 3.3 3.4 7.2 0.0 2.9 3 0 0 3 3 3 0 Kelch motif Kelch_3 PF13415.1 ETO30323.1 - 0.062 13.4 0.0 0.65 10.2 0.0 2.7 3 0 0 3 3 3 0 Galactose oxidase, central domain EF-hand_7 PF13499.1 ETO30324.1 - 2.9e-10 40.1 4.1 1.3e-06 28.4 0.2 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO30324.1 - 6.7e-06 25.5 0.1 0.0013 18.4 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 ETO30324.1 - 2.3e-05 23.3 0.1 0.0043 16.2 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_10 PF14788.1 ETO30324.1 - 0.0015 18.1 0.5 0.052 13.2 0.3 2.3 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.4 ETO30324.1 - 0.0058 16.6 1.1 0.13 12.2 0.4 2.2 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.1 ETO30324.1 - 0.011 15.0 0.1 1.9 7.9 0.1 2.5 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.1 ETO30324.1 - 0.043 13.4 0.0 9.8 5.8 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair BCNT PF07572.7 ETO30324.1 - 0.063 13.2 0.2 1.4 8.9 0.2 2.4 2 0 0 2 2 2 0 Bucentaur or craniofacial development DUF2205 PF10224.4 ETO30324.1 - 0.092 12.3 1.2 7 6.3 0.0 2.7 2 1 1 3 3 3 0 Predicted coiled-coil protein (DUF2205) APOBEC_C PF05240.9 ETO30325.1 - 0.027 13.8 1.0 0.11 11.9 0.7 2.0 1 0 0 1 1 1 0 APOBEC-like C-terminal domain 2-Hacid_dh PF00389.25 ETO30325.1 - 0.039 13.4 0.0 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain tRNA_lig_kinase PF08303.6 ETO30326.1 - 0.03 14.1 0.5 0.042 13.7 0.4 1.5 1 1 0 1 1 1 0 tRNA ligase kinase domain 7TM_GPCR_Sru PF10322.4 ETO30326.1 - 0.065 12.3 0.0 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru LRR_6 PF13516.1 ETO30327.1 - 0.0044 16.9 5.8 0.079 13.0 0.1 3.7 3 0 0 3 3 3 2 Leucine Rich repeat Ank_4 PF13637.1 ETO30328.1 - 4.2e-17 62.1 0.9 1.1e-08 35.3 0.2 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO30328.1 - 2.1e-11 43.6 0.2 7.5e-08 32.3 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO30328.1 - 6.5e-11 42.4 0.2 1.9e-09 37.7 0.1 2.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO30328.1 - 1.4e-09 37.2 0.7 8e-07 28.7 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeat DUF294 PF03445.8 ETO30328.1 - 5.7e-08 32.4 0.0 1.1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Putative nucleotidyltransferase DUF294 Ank PF00023.25 ETO30328.1 - 2.1e-07 30.3 0.1 1.9e-06 27.4 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeat NTP_transf_2 PF01909.18 ETO30328.1 - 0.0083 16.4 0.0 0.024 14.9 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Fibrinogen_C PF00147.13 ETO30328.1 - 0.12 11.9 0.1 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Fibrinogen beta and gamma chains, C-terminal globular domain WD40 PF00400.27 ETO30329.1 - 3.6e-76 248.5 14.9 5.6e-12 45.0 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat PD40 PF07676.7 ETO30329.1 - 4.6e-06 26.1 2.0 6.2 6.5 0.0 5.4 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO30329.1 - 6.4e-06 24.5 12.1 0.16 10.0 0.1 5.6 1 1 4 5 5 5 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO30329.1 - 0.00016 20.1 0.2 0.032 12.5 0.0 2.6 2 1 0 2 2 2 2 Cytochrome D1 heme domain Kelch_6 PF13964.1 ETO30329.1 - 0.00074 19.5 6.6 0.051 13.7 0.3 5.1 5 1 0 5 5 5 1 Kelch motif Kelch_1 PF01344.20 ETO30329.1 - 0.019 14.5 2.0 0.031 13.8 0.2 2.3 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.1 ETO30329.1 - 0.024 14.5 3.7 1.2 9.1 0.0 3.7 3 0 0 3 3 3 0 Kelch motif Proteasome_A_N PF10584.4 ETO30329.1 - 0.03 13.6 2.3 22 4.5 0.0 4.7 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Nbas_N PF15492.1 ETO30329.1 - 0.036 13.1 0.6 8.8 5.3 0.0 3.7 2 1 3 5 5 5 0 Neuroblastoma-amplified sequence, N terminal Kelch_2 PF07646.10 ETO30329.1 - 0.076 12.8 1.5 7 6.5 0.1 3.9 4 0 0 4 4 4 0 Kelch motif WD40 PF00400.27 ETO30330.1 - 4e-82 267.4 14.7 5.7e-12 45.0 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO30330.1 - 4.4e-07 28.4 5.6 0.083 11.0 0.1 5.1 2 1 3 5 5 5 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO30330.1 - 9.1e-05 22.0 0.1 0.0043 16.5 0.1 2.5 1 1 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO30330.1 - 0.00011 20.6 1.3 0.34 9.1 0.0 3.5 1 1 2 4 4 4 2 Cytochrome D1 heme domain DUF3601 PF12208.3 ETO30330.1 - 0.00038 20.3 0.3 13 5.8 0.0 5.1 4 2 2 6 6 6 1 Domain of unknown function (DUF3601) Nbas_N PF15492.1 ETO30330.1 - 0.00042 19.5 1.7 3.4 6.6 0.0 3.9 1 1 4 5 5 5 2 Neuroblastoma-amplified sequence, N terminal Str_synth PF03088.11 ETO30330.1 - 0.00045 20.1 0.7 3.2 7.8 0.1 4.5 3 2 1 5 5 5 1 Strictosidine synthase PLD_C PF12357.3 ETO30330.1 - 0.0012 18.3 0.6 7.7 6.1 0.0 4.6 5 0 0 5 5 5 1 Phospholipase D C terminal ROS_MUCR PF05443.6 ETO30330.1 - 0.0099 15.6 0.1 1 9.1 0.0 3.2 2 1 1 3 3 3 1 ROS/MUCR transcriptional regulator protein Ribosomal_L21p PF00829.16 ETO30330.1 - 0.075 13.1 0.0 34 4.6 0.0 3.9 4 0 0 4 4 4 0 Ribosomal prokaryotic L21 protein PD40 PF07676.7 ETO30330.1 - 0.66 9.7 3.4 19 5.0 0.0 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat OSTbeta PF15048.1 ETO30332.1 - 0.16 12.0 0.0 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein UQ_con PF00179.21 ETO30335.1 - 1.1e-16 60.5 1.1 1.7e-16 59.8 0.8 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CBF PF03914.12 ETO30336.1 - 1.2e-22 80.1 0.1 2.9e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 CBF/Mak21 family NOC3p PF07540.6 ETO30336.1 - 4.4e-08 33.2 2.1 7e-08 32.6 0.3 2.3 2 0 0 2 2 2 1 Nucleolar complex-associated protein HEAT PF02985.17 ETO30336.1 - 0.017 15.1 0.1 5.3 7.3 0.0 2.7 2 0 0 2 2 2 0 HEAT repeat HEAT_2 PF13646.1 ETO30336.1 - 0.085 13.1 0.0 12 6.2 0.0 2.6 2 0 0 2 2 2 0 HEAT repeats DUF4660 PF15559.1 ETO30337.1 - 0.039 14.0 1.1 0.094 12.8 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4660) Sigma70_ner PF04546.8 ETO30337.1 - 1.5 8.3 8.3 1.8 8.1 5.7 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region TLD PF07534.11 ETO30338.1 - 1.1e-13 51.3 0.4 2.1e-13 50.4 0.3 1.4 1 0 0 1 1 1 1 TLD Pirin PF02678.11 ETO30339.1 - 0.032 14.1 0.1 0.13 12.1 0.1 2.0 1 1 1 2 2 2 0 Pirin Clp1 PF06807.9 ETO30340.1 - 3.2e-18 66.2 0.5 1.1e-17 64.4 0.4 1.9 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 ETO30340.1 - 2.3e-08 33.8 0.0 9.7e-08 31.8 0.0 2.1 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 ETO30340.1 - 0.018 15.8 0.5 0.07 13.9 0.1 2.4 2 1 0 2 2 2 0 AAA domain DUF3439 PF11921.3 ETO30340.1 - 0.23 11.1 6.7 0.58 9.9 4.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) BUD22 PF09073.5 ETO30340.1 - 0.82 8.6 5.5 1.6 7.6 3.8 1.5 1 1 0 1 1 1 0 BUD22 DUF2763 PF10961.3 ETO30340.1 - 1.1 9.7 6.6 4.9 7.6 4.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) ELMO_CED12 PF04727.8 ETO30341.1 - 4.3e-09 36.1 1.9 2.3e-07 30.5 1.3 2.4 1 1 0 1 1 1 1 ELMO/CED-12 family EF-hand_7 PF13499.1 ETO30342.1 - 5.7e-22 77.6 2.5 1.1e-13 51.0 0.6 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 ETO30342.1 - 1.6e-21 73.9 5.2 1.2e-06 27.3 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.1 ETO30342.1 - 7.3e-18 63.0 9.4 2.8e-06 26.3 0.1 4.2 3 1 1 4 4 4 3 EF hand EF-hand_6 PF13405.1 ETO30342.1 - 3.4e-17 60.7 4.2 6.2e-06 25.6 0.0 4.1 3 1 1 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 ETO30342.1 - 8e-17 60.5 6.9 2.1e-08 33.6 1.0 3.4 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 ETO30342.1 - 8.8e-08 32.1 0.1 2.6e-05 24.2 0.0 2.4 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 ETO30342.1 - 1.4e-06 28.0 0.4 0.0083 15.8 0.0 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 ETO30342.1 - 0.00078 19.3 0.0 0.17 11.8 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_10 PF14788.1 ETO30342.1 - 0.034 13.8 0.4 1.6 8.4 0.0 2.9 3 0 0 3 3 3 0 EF hand Syd PF07348.7 ETO30342.1 - 0.049 12.9 0.0 0.087 12.1 0.0 1.4 1 0 0 1 1 1 0 Syd protein (SUKH-2) DUF3349 PF11829.3 ETO30342.1 - 0.13 12.7 0.2 2.7 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) MAP7 PF05672.6 ETO30342.1 - 0.18 11.1 1.0 8.3 5.7 0.3 2.2 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family DUF262 PF03235.9 ETO30343.1 - 0.021 14.8 0.7 0.021 14.8 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF262 Salp15 PF12115.3 ETO30343.1 - 0.08 13.1 7.0 0.03 14.5 2.0 2.4 2 2 0 2 2 2 0 Salivary protein of 15kDa inhibits CD4+ T cell activation Treacle PF03546.9 ETO30343.1 - 0.21 10.3 3.6 0.29 9.8 2.5 1.1 1 0 0 1 1 1 0 Treacher Collins syndrome protein Treacle Peptidase_S9 PF00326.16 ETO30344.1 - 5.3e-25 87.8 0.0 6.1e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 ETO30344.1 - 7.6e-07 29.2 0.0 1.2e-06 28.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 ETO30344.1 - 6.9e-05 22.5 0.0 0.0001 21.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 ETO30344.1 - 0.00011 21.6 0.0 0.00014 21.2 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 ETO30344.1 - 0.00021 20.8 0.1 0.018 14.6 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETO30344.1 - 0.00082 19.1 0.0 0.001 18.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family PhoPQ_related PF10142.4 ETO30344.1 - 0.0087 14.5 0.0 0.011 14.2 0.0 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Tannase PF07519.6 ETO30344.1 - 0.053 12.2 0.0 0.37 9.4 0.0 1.9 2 0 0 2 2 2 0 Tannase and feruloyl esterase Orbi_NS1 PF01718.11 ETO30344.1 - 0.068 11.1 0.1 0.092 10.7 0.0 1.2 1 0 0 1 1 1 0 Orbivirus non-structural protein NS1, or hydrophobic tubular protein DUF2920 PF11144.3 ETO30344.1 - 0.086 11.8 0.0 1.6 7.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Abhydrolase_2 PF02230.11 ETO30344.1 - 0.12 11.8 0.0 1.6 8.1 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Tubulin_C PF03953.12 ETO30345.1 - 1.1e-29 103.0 0.0 1.5e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain DUF1464 PF07318.7 ETO30346.1 - 0.075 11.8 0.2 0.14 10.9 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1464) ABC_tran PF00005.22 ETO30347.1 - 0.0034 17.7 0.0 0.0034 17.7 0.0 5.8 6 1 0 6 6 6 1 ABC transporter AAA_22 PF13401.1 ETO30347.1 - 0.021 14.9 0.8 3.2 7.8 0.0 4.4 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 ETO30347.1 - 0.096 12.2 0.1 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 ETO30347.1 - 0.28 10.9 0.1 0.77 9.5 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain SecA_DEAD PF07517.9 ETO30348.1 - 7.9e-12 45.0 0.6 1.3e-10 41.0 0.0 2.8 3 1 0 3 3 3 1 SecA DEAD-like domain Helicase_C PF00271.26 ETO30348.1 - 0.0045 16.8 0.0 0.014 15.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain YqgF PF14639.1 ETO30348.1 - 0.049 13.1 1.8 1.4 8.4 0.1 2.8 2 0 0 2 2 2 0 Holliday-junction resolvase-like of SPT6 DUF2413 PF10310.4 ETO30349.1 - 0.018 13.8 9.9 0.019 13.7 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Trypan_PARP PF05887.6 ETO30349.1 - 7.3 6.4 10.9 11 5.7 7.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TMF_TATA_bd PF12325.3 ETO30350.1 - 9.6e-05 22.0 10.9 9.6e-05 22.0 7.6 4.2 3 1 1 4 4 4 1 TATA element modulatory factor 1 TATA binding Cep57_CLD_2 PF14197.1 ETO30350.1 - 0.003 17.4 34.0 0.18 11.7 1.7 4.7 4 1 0 4 4 4 3 Centrosome localisation domain of PPC89 LPP PF04728.8 ETO30350.1 - 0.09 12.5 4.3 27 4.6 0.1 4.4 3 1 1 4 4 4 0 Lipoprotein leucine-zipper WD40_alt PF14077.1 ETO30350.1 - 0.32 10.6 5.9 2.3 7.8 0.4 4.3 4 1 1 5 5 5 0 Alternative WD40 repeat motif BBP1_C PF15272.1 ETO30350.1 - 6.1 6.3 40.0 0.18 11.3 6.0 3.9 1 1 3 4 4 4 0 Spindle pole body component BBP1, C-terminal Laminin_G_3 PF13385.1 ETO30351.1 - 0.04 14.1 0.1 0.14 12.3 0.1 1.9 1 1 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily TNF PF00229.13 ETO30351.1 - 0.08 12.5 0.1 1.4 8.4 0.1 2.2 1 1 0 1 1 1 0 TNF(Tumour Necrosis Factor) family WD40 PF00400.27 ETO30353.1 - 4.3e-28 96.1 5.3 1e-09 37.8 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO30353.1 - 0.001 17.3 1.4 0.38 8.8 0.0 2.5 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Trypan_PARP PF05887.6 ETO30354.1 - 3.7 7.3 21.2 0.94 9.2 11.2 2.7 2 1 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Clathrin PF00637.15 ETO30355.1 - 2.7e-86 286.4 16.2 1.1e-29 102.9 1.7 3.1 3 0 0 3 3 3 3 Region in Clathrin and VPS TPR_14 PF13428.1 ETO30355.1 - 0.00022 21.5 1.2 1.6 9.6 0.0 4.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO30355.1 - 0.036 13.7 5.2 0.28 10.8 0.4 3.3 3 1 0 3 3 3 0 TPR repeat Methyltransf_12 PF08242.7 ETO30356.1 - 4 7.9 6.3 2 8.9 0.4 2.9 2 1 1 3 3 3 0 Methyltransferase domain TSC22 PF01166.13 ETO30357.1 - 0.00089 19.1 23.7 0.049 13.5 0.3 5.0 4 1 0 4 4 4 4 TSC-22/dip/bun family Myosin_tail_1 PF01576.14 ETO30358.1 - 0.047 11.4 57.1 0.069 10.8 16.0 2.2 1 1 1 2 2 2 0 Myosin tail DUF3584 PF12128.3 ETO30358.1 - 2.3 5.4 51.5 0.2 8.9 19.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 ETO30358.1 - 2.3 7.3 11.9 0.36 9.9 3.2 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF4094 PF13334.1 ETO30359.1 - 0.025 14.9 0.9 0.025 14.9 0.6 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4094) NAF PF03822.9 ETO30359.1 - 0.16 11.6 2.7 1.3 8.7 0.0 2.8 2 0 0 2 2 2 0 NAF domain Pkinase PF00069.20 ETO30360.1 - 3.7e-14 52.5 3.0 4.5e-14 52.2 2.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO30360.1 - 2e-10 40.2 2.5 2e-10 40.1 1.7 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_VLTF3 PF04947.9 ETO30360.1 - 0.041 13.3 2.5 0.052 13.0 1.8 1.2 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like RTP PF02334.11 ETO30360.1 - 0.095 12.6 3.5 0.11 12.4 2.4 1.1 1 0 0 1 1 1 0 Replication terminator protein DDE_Tnp_1_3 PF13612.1 ETO30360.1 - 0.15 11.8 2.0 0.21 11.3 1.4 1.3 1 0 0 1 1 1 0 Transposase DDE domain Pyr_redox_dim PF02852.17 ETO30361.1 - 3.4e-27 94.6 0.0 1.4e-26 92.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 ETO30361.1 - 2.3e-20 73.3 0.0 1.2e-19 71.0 0.0 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETO30361.1 - 2.2e-16 60.0 0.2 5.5e-16 58.7 0.2 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 ETO30361.1 - 9.8e-06 25.3 0.2 2e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 ETO30361.1 - 0.001 18.2 0.0 0.0021 17.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 ETO30361.1 - 0.004 17.2 0.0 0.17 11.9 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETO30361.1 - 0.033 13.0 0.0 2.4 7.0 0.0 2.1 1 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) ThiF PF00899.16 ETO30361.1 - 0.037 13.8 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 ThiF family CPSase_L_chain PF00289.17 ETO30361.1 - 0.049 13.7 0.0 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain F420_oxidored PF03807.12 ETO30361.1 - 0.095 13.1 0.0 0.3 11.5 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DEP PF00610.16 ETO30362.1 - 9.5e-11 41.2 0.1 1.7e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Seryl_tRNA_N PF02403.17 ETO30363.1 - 3.9 7.5 15.1 0.23 11.5 3.5 2.6 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain PLRV_ORF5 PF01690.12 ETO30364.1 - 0.81 8.7 9.1 0.99 8.4 6.3 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein TP53IP5 PF15331.1 ETO30364.1 - 0.9 9.4 12.6 1.3 8.9 8.8 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Dynamin_M PF01031.15 ETO30365.1 - 4.9e-90 301.2 1.9 3.5e-48 163.8 0.1 2.4 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.18 ETO30365.1 - 4.8e-29 101.3 0.9 6.9e-28 97.5 0.0 2.6 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 ETO30365.1 - 6.8e-28 96.4 2.6 6.8e-28 96.4 1.8 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain TFIIA PF03153.8 ETO30365.1 - 0.02 14.7 23.3 0.04 13.8 16.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 ETO30365.1 - 0.049 11.9 32.5 0.0057 15.0 17.6 2.1 2 0 0 2 2 2 0 Transmembrane protein DUF605 PF04652.11 ETO30365.1 - 0.18 11.1 29.1 0.033 13.5 16.7 1.9 2 0 0 2 2 2 0 Vta1 like DUF2972 PF11186.3 ETO30365.1 - 0.29 11.0 0.0 0.29 11.0 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF2972) SprA-related PF12118.3 ETO30365.1 - 0.79 8.9 39.7 0.1 11.9 24.0 1.8 2 0 0 2 2 2 0 SprA-related family XPG_I PF00867.13 ETO30367.1 - 2.2e-24 85.3 0.0 1.2e-23 82.9 0.0 2.4 1 1 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 ETO30367.1 - 3.9e-06 26.5 0.0 1.4e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 XPG domain containing 5_3_exonuc PF01367.15 ETO30367.1 - 0.0019 18.3 0.0 0.0084 16.3 0.0 2.1 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Toxin_39 PF15500.1 ETO30367.1 - 0.025 14.7 0.2 0.086 12.9 0.1 2.0 1 0 0 1 1 1 0 Putative RNase-like toxin DUF3966 PF13110.1 ETO30367.1 - 0.031 14.0 0.4 0.13 12.1 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3966) HHH PF00633.18 ETO30367.1 - 0.053 13.2 0.0 0.19 11.5 0.0 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix motif Ndr PF03096.9 ETO30368.1 - 5.2e-35 120.2 0.0 6.6e-35 119.9 0.0 1.1 1 0 0 1 1 1 1 Ndr family Abhydrolase_6 PF12697.2 ETO30368.1 - 3e-06 27.2 0.0 3.8e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family CDC45 PF02724.9 ETO30369.1 - 1.4 6.8 17.0 1.7 6.5 11.8 1.3 1 0 0 1 1 1 0 CDC45-like protein EzrA PF06160.7 ETO30370.1 - 4.4e-05 21.8 23.2 0.00076 17.7 6.7 2.3 2 0 0 2 2 2 2 Septation ring formation regulator, EzrA CCDC155 PF14662.1 ETO30370.1 - 0.0017 17.9 36.2 0.0054 16.3 9.5 2.6 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 CENP-F_leu_zip PF10473.4 ETO30370.1 - 0.0034 17.2 30.9 0.49 10.2 6.0 3.5 2 1 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.4 ETO30370.1 - 0.0061 16.6 5.2 0.0061 16.6 3.6 4.8 3 2 3 6 6 6 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Filament PF00038.16 ETO30370.1 - 0.018 14.5 31.1 0.48 9.8 4.1 3.5 2 2 1 3 3 3 0 Intermediate filament protein DUF972 PF06156.8 ETO30370.1 - 0.022 15.0 34.3 0.024 14.9 4.6 4.5 1 1 3 4 4 4 0 Protein of unknown function (DUF972) APG6 PF04111.7 ETO30370.1 - 0.029 13.4 32.1 0.065 12.2 9.2 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 GAS PF13851.1 ETO30370.1 - 0.055 12.6 32.5 0.072 12.2 8.4 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TSC22 PF01166.13 ETO30370.1 - 0.084 12.8 0.3 0.084 12.8 0.2 5.4 3 2 2 5 5 5 0 TSC-22/dip/bun family SecIII_SopE_N PF05364.9 ETO30370.1 - 0.11 12.3 3.9 0.18 11.6 0.7 2.8 1 1 1 2 2 2 0 Salmonella type III secretion SopE effector N-terminus DUF2353 PF09789.4 ETO30370.1 - 0.13 11.4 31.7 0.57 9.3 12.3 2.3 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) HALZ PF02183.13 ETO30370.1 - 0.13 11.9 31.6 0.16 11.7 0.3 6.5 4 2 2 6 6 6 0 Homeobox associated leucine zipper Myosin_tail_1 PF01576.14 ETO30370.1 - 0.2 9.3 32.3 0.61 7.7 22.4 1.7 1 1 0 1 1 1 0 Myosin tail Cortex-I_coil PF09304.5 ETO30370.1 - 0.21 11.6 29.5 0.54 10.3 6.9 3.0 2 1 0 2 2 2 0 Cortexillin I, coiled coil DUF1664 PF07889.7 ETO30370.1 - 0.23 11.2 20.7 0.24 11.2 2.9 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) FlgN PF05130.7 ETO30370.1 - 0.36 11.0 25.1 0.22 11.7 5.8 3.7 2 2 1 3 3 3 0 FlgN protein DASH_Dam1 PF08653.5 ETO30370.1 - 0.54 10.0 12.5 3.2 7.5 0.1 4.9 3 2 2 5 5 5 0 DASH complex subunit Dam1 bZIP_1 PF00170.16 ETO30370.1 - 0.8 9.7 29.3 0.091 12.7 1.5 5.4 3 2 1 5 5 5 0 bZIP transcription factor H-kinase_dim PF02895.9 ETO30370.1 - 1.2 9.5 17.7 3.7 7.9 0.2 4.2 3 2 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain Atg14 PF10186.4 ETO30370.1 - 1.3 7.8 32.2 1.6 7.5 4.4 3.1 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 ETO30370.1 - 2.4 5.9 25.9 2 6.2 7.5 2.2 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Reo_sigmaC PF04582.7 ETO30370.1 - 2.4 7.2 19.9 8.8 5.4 2.9 2.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF948 PF06103.6 ETO30370.1 - 3.3 7.6 18.7 3.4 7.6 0.3 4.8 2 1 2 5 5 5 0 Bacterial protein of unknown function (DUF948) ERM PF00769.14 ETO30370.1 - 5.5 6.4 24.5 1.5 8.2 4.2 3.1 1 1 2 3 3 3 0 Ezrin/radixin/moesin family SlyX PF04102.7 ETO30370.1 - 5.8 7.3 20.4 0.67 10.3 0.8 5.1 2 2 2 4 4 4 0 SlyX DUF4140 PF13600.1 ETO30370.1 - 6.6 7.2 13.5 21 5.6 0.2 4.1 2 2 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) CHASE3 PF05227.8 ETO30370.1 - 7 6.3 9.2 1.1 8.9 1.6 2.8 2 2 1 3 3 3 0 CHASE3 domain Fzo_mitofusin PF04799.8 ETO30370.1 - 8.8 5.6 25.4 0.27 10.5 4.3 3.2 1 1 0 2 2 2 0 fzo-like conserved region DUF2972 PF11186.3 ETO30373.1 - 0.015 15.2 1.2 0.015 15.2 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2972) Plant_all_beta PF10532.4 ETO30373.1 - 0.076 13.0 4.4 1.6 8.8 1.1 2.1 2 0 0 2 2 2 0 Plant specific N-all beta domain NUDIX PF00293.23 ETO30374.1 - 2.8e-12 46.4 0.0 6.3e-12 45.2 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain Orn_Arg_deC_N PF02784.11 ETO30375.1 - 5.6e-44 150.2 0.2 5.7e-43 146.9 0.1 2.2 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain DUF2208 PF09973.4 ETO30375.1 - 0.007 15.6 0.6 0.013 14.7 0.4 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2208) Integrase_Zn PF02022.14 ETO30375.1 - 0.053 12.9 0.0 0.16 11.4 0.0 1.8 1 0 0 1 1 1 0 Integrase Zinc binding domain Orn_DAP_Arg_deC PF00278.17 ETO30375.1 - 0.092 12.4 0.6 0.59 9.8 0.1 2.4 2 1 1 3 3 3 0 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Aldedh PF00171.17 ETO30377.1 - 2.6e-38 131.5 0.0 3.7e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Kelch_6 PF13964.1 ETO30379.1 - 7.3e-05 22.7 1.5 0.0015 18.6 0.0 3.3 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 ETO30379.1 - 0.0021 17.5 2.0 0.012 15.0 0.1 2.8 2 1 0 2 2 2 1 Kelch motif SPC25 PF06703.6 ETO30379.1 - 0.14 11.7 4.0 0.26 10.8 2.8 1.4 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF3671 PF12420.3 ETO30381.1 - 0.087 12.8 1.5 0.13 12.2 0.6 1.7 1 1 0 2 2 2 0 Protein of unknown function PGM_PMM_II PF02879.11 ETO30383.1 - 2.1e-07 31.1 0.0 5.2e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_I PF02878.11 ETO30383.1 - 2.1e-07 30.4 0.0 3.9e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I TMEM192 PF14802.1 ETO30384.1 - 0.11 11.2 5.0 0.046 12.5 1.7 1.6 1 1 1 2 2 2 0 TMEM192 family DUF3816 PF12822.2 ETO30384.1 - 0.13 12.1 7.9 0.72 9.7 5.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) Guanylate_cyc PF00211.15 ETO30385.1 - 1.9e-24 86.0 0.0 2.4e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF2453 PF10507.4 ETO30385.1 - 0.023 14.5 0.0 0.061 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2453) WD40 PF00400.27 ETO30386.1 - 3.6e-15 55.1 17.8 1.7e-06 27.6 0.2 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 ETO30386.1 - 6.2e-08 32.5 0.1 0.00015 21.5 0.0 2.7 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A CaM-KIIN PF15170.1 ETO30386.1 - 0.0029 17.5 0.0 0.011 15.7 0.0 1.9 2 0 0 2 2 2 1 Calcium/calmodulin-dependent protein kinase II inhibitor Sec66 PF09802.4 ETO30388.1 - 1.7e-08 34.1 0.6 1.7e-08 34.1 0.4 1.8 2 0 0 2 2 2 1 Preprotein translocase subunit Sec66 Phage_min_cap2 PF06152.6 ETO30388.1 - 0.51 9.2 4.0 2.8 6.8 0.6 2.1 2 0 0 2 2 2 0 Phage minor capsid protein 2 DUF4530 PF15039.1 ETO30388.1 - 5.5 6.9 9.5 2.6 8.0 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4530) TPR_11 PF13414.1 ETO30389.1 - 0.0056 16.2 7.4 0.43 10.2 2.0 3.6 2 1 1 3 3 3 3 TPR repeat TPR_12 PF13424.1 ETO30389.1 - 0.036 13.9 5.2 5.4 7.0 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETO30389.1 - 0.053 14.1 0.1 3.4 8.5 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETO30389.1 - 0.31 11.0 12.1 5 7.2 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETO30389.1 - 0.84 9.3 12.1 7.7 6.3 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat HTH_Tnp_Mu_2 PF09039.6 ETO30390.1 - 0.0062 16.2 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Mu DNA binding, I gamma subdomain Clr5 PF14420.1 ETO30390.1 - 0.097 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Clr5 domain Apis_Csd PF11671.3 ETO30390.1 - 0.29 10.9 5.0 0.42 10.3 3.5 1.4 1 0 0 1 1 1 0 Complementary sex determiner protein Ribosomal_L20 PF00453.13 ETO30391.1 - 0.046 13.6 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein L20 Filo_VP35 PF02097.10 ETO30392.1 - 0.0016 17.7 1.3 0.0019 17.4 0.9 1.1 1 0 0 1 1 1 1 Filoviridae VP35 DegS PF05384.6 ETO30392.1 - 0.0029 16.8 7.3 0.18 11.0 0.1 2.2 1 1 1 2 2 2 2 Sensor protein DegS BRE1 PF08647.6 ETO30392.1 - 0.014 15.3 0.3 0.014 15.3 0.2 2.6 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase SDH_alpha PF03313.10 ETO30392.1 - 0.056 12.4 1.0 0.069 12.1 0.7 1.1 1 0 0 1 1 1 0 Serine dehydratase alpha chain OEP PF02321.13 ETO30392.1 - 0.085 12.4 9.5 0.49 9.9 6.5 1.9 1 1 0 1 1 1 0 Outer membrane efflux protein Baculo_PEP_C PF04513.7 ETO30392.1 - 0.093 12.5 1.2 0.12 12.1 0.8 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TINF2_N PF14973.1 ETO30392.1 - 0.093 12.8 7.1 0.11 12.6 2.6 2.0 2 0 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus Tropomyosin PF00261.15 ETO30392.1 - 0.1 11.6 8.3 0.061 12.4 2.8 2.1 1 1 1 2 2 2 0 Tropomyosin FliJ PF02050.11 ETO30392.1 - 0.17 11.9 7.6 0.29 11.2 3.6 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein DUF2693 PF10902.3 ETO30392.1 - 0.24 11.3 2.3 0.74 9.7 0.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2693) Phage_GP20 PF06810.6 ETO30392.1 - 0.3 10.4 13.5 0.87 9.0 0.3 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 MscS_porin PF12795.2 ETO30392.1 - 0.36 10.1 11.6 0.93 8.7 8.0 1.7 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF3763 PF12592.3 ETO30392.1 - 0.41 10.3 0.1 0.41 10.3 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3763) V-SNARE PF05008.10 ETO30392.1 - 0.53 10.4 6.7 0.31 11.2 0.3 2.8 1 1 2 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Spatacsin_C PF14649.1 ETO30392.1 - 0.71 8.6 8.4 0.42 9.4 3.8 1.8 1 1 1 2 2 2 0 Spatacsin C-terminus Endotoxin_N PF03945.9 ETO30392.1 - 0.82 9.0 6.9 0.46 9.8 1.8 1.9 1 1 1 2 2 2 0 delta endotoxin, N-terminal domain ACCA PF03255.9 ETO30392.1 - 1.4 8.4 5.8 0.7 9.4 0.9 2.2 1 1 2 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF1319 PF07028.6 ETO30392.1 - 1.7 8.8 9.9 0.33 11.1 1.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) DUF1754 PF08555.5 ETO30392.1 - 4.8 7.8 14.6 2.6e+02 2.3 10.1 2.3 1 1 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) DUF3847 PF12958.2 ETO30392.1 - 5.2 6.8 8.7 5.1 6.9 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3847) MRP-L46 PF11788.3 ETO30392.1 - 6.1 7.5 8.1 20 5.8 0.7 2.3 2 1 0 2 2 2 0 39S mitochondrial ribosomal protein L46 HR1 PF02185.11 ETO30392.1 - 9.1 6.1 9.9 11 5.8 0.4 3.3 2 1 0 2 2 2 0 Hr1 repeat HAD_2 PF13419.1 ETO30393.1 - 0.011 16.0 0.0 0.072 13.3 0.0 2.2 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DHC_N2 PF08393.8 ETO30394.1 - 1.1e-84 284.3 6.9 1.4e-84 284.0 4.8 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 Nab2 PF11517.3 ETO30394.1 - 0.05 13.6 0.3 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) ArsA_ATPase PF02374.10 ETO30395.1 - 0.016 14.3 0.4 0.019 14.0 0.3 1.1 1 0 0 1 1 1 0 Anion-transporting ATPase Mad3_BUB1_I PF08311.7 ETO30395.1 - 0.072 12.8 2.5 0.094 12.4 1.7 1.2 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 PYC_OADA PF02436.13 ETO30395.1 - 0.39 10.1 2.6 0.44 9.9 1.8 1.0 1 0 0 1 1 1 0 Conserved carboxylase domain C1_2 PF03107.11 ETO30396.1 - 0.0076 16.3 5.1 0.0076 16.3 3.6 2.0 2 0 0 2 2 2 1 C1 domain Ydc2-catalyt PF09159.5 ETO30396.1 - 0.055 12.9 1.2 0.062 12.7 0.8 1.1 1 0 0 1 1 1 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 PAS_10 PF13596.1 ETO30396.1 - 0.11 12.8 0.1 0.28 11.4 0.0 1.7 2 0 0 2 2 2 0 PAS domain ComGG PF14173.1 ETO30396.1 - 0.27 11.4 4.2 0.62 10.2 1.9 2.0 2 0 0 2 2 2 0 ComG operon protein 7 RNHCP PF12647.2 ETO30396.1 - 1.6 8.6 6.1 0.35 10.7 1.5 2.0 2 0 0 2 2 2 0 RNHCP domain DZR PF12773.2 ETO30396.1 - 3.7 7.4 10.5 28 4.6 7.3 2.4 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 ETO30396.1 - 5 6.4 6.7 6.2 6.1 2.5 2.6 2 1 0 2 2 2 0 zinc-ribbon domain TFIIA PF03153.8 ETO30397.1 - 0.0014 18.6 27.6 0.0014 18.6 19.1 1.7 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Mucin PF01456.12 ETO30397.1 - 0.47 10.2 18.1 0.92 9.2 12.6 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein CDC27 PF09507.5 ETO30397.1 - 9.5 5.3 35.1 15 4.6 24.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Proteasome PF00227.21 ETO30398.1 - 1e-38 132.5 0.0 6.2e-21 74.5 0.0 3.2 3 0 0 3 3 3 3 Proteasome subunit Proteasome_A_N PF10584.4 ETO30398.1 - 3e-09 36.0 0.0 5.3e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF1743 PF08489.6 ETO30398.1 - 0.16 11.7 0.4 5.2 6.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1743) Ion_trans PF00520.26 ETO30399.1 - 2e-08 33.7 27.9 2.4e-08 33.4 18.4 1.8 1 1 0 1 1 1 1 Ion transport protein DUF4131 PF13567.1 ETO30399.1 - 0.99 8.7 6.2 3.2 7.1 2.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DEAD PF00270.24 ETO30400.1 - 2.5e-12 46.5 0.2 8.5e-12 44.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF1840 PF08895.6 ETO30400.1 - 0.073 13.1 2.9 0.14 12.2 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) RolB_RolC PF02027.12 ETO30400.1 - 0.076 12.1 0.0 0.25 10.4 0.0 1.8 2 0 0 2 2 2 0 RolB/RolC glucosidase family RP-C_C PF11800.3 ETO30400.1 - 0.23 11.1 4.2 0.44 10.2 2.9 1.5 1 0 0 1 1 1 0 Replication protein C C-terminal region Hom_end_hint PF05203.11 ETO30400.1 - 1.6 8.3 7.5 2.6 7.7 5.2 1.3 1 0 0 1 1 1 0 Hom_end-associated Hint DUF1998 PF09369.5 ETO30401.1 - 3.5e-10 40.3 0.1 9.6e-09 35.6 0.0 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 ETO30401.1 - 1.5e-07 31.1 0.0 4.7e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETO30401.1 - 1.1e-05 24.9 1.6 2.3e-05 23.9 0.0 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase Sad1_UNC PF07738.8 ETO30402.1 - 0.00011 22.0 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Sulfotransfer_2 PF03567.9 ETO30402.1 - 0.0025 17.5 0.1 0.095 12.3 0.0 2.1 2 0 0 2 2 2 2 Sulfotransferase family SR-25 PF10500.4 ETO30403.1 - 0.0006 19.3 11.9 0.00068 19.1 8.2 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Period_C PF12114.3 ETO30403.1 - 0.35 10.4 8.9 0.44 10.1 6.1 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Secretin_N_2 PF07655.8 ETO30403.1 - 0.48 10.8 12.5 0.57 10.6 3.9 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain CAF-1_p150 PF11600.3 ETO30403.1 - 3.9 6.7 6.9 4.6 6.5 4.8 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF508 PF04370.7 ETO30403.1 - 6.4 6.3 8.3 9.1 5.8 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF508) PUB PF09409.5 ETO30404.1 - 1.1e-10 41.0 0.4 6.4e-10 38.6 0.0 2.4 3 0 0 3 3 2 1 PUB domain Methyltransf_31 PF13847.1 ETO30404.1 - 6.2e-07 29.1 0.0 1.5e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETO30404.1 - 6.4e-07 29.7 0.0 1.8e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETO30404.1 - 2.3e-06 27.8 0.0 5.4e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETO30404.1 - 1e-05 24.9 0.0 2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 ETO30404.1 - 3.2e-05 24.3 0.3 8e-05 23.0 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO30404.1 - 3.6e-05 24.3 0.0 9.3e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 ETO30404.1 - 3.8e-05 23.4 0.0 9.4e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 ETO30404.1 - 0.0013 18.0 0.0 0.01 15.1 0.0 2.1 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_23 PF13489.1 ETO30404.1 - 0.0053 16.5 0.0 0.0096 15.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETO30404.1 - 0.014 15.4 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 ETO30404.1 - 0.021 13.9 0.0 0.037 13.1 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase EIIBC-GUT_N PF03612.9 ETO30404.1 - 0.032 13.8 0.2 0.061 12.9 0.1 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Ubie_methyltran PF01209.13 ETO30404.1 - 0.054 12.6 0.0 0.093 11.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family HATPase_c PF02518.21 ETO30404.1 - 0.078 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TraH_2 PF06871.6 ETO30404.1 - 0.15 11.4 0.3 0.26 10.7 0.2 1.2 1 0 0 1 1 1 0 TraH_2 Myc_N PF01056.13 ETO30404.1 - 0.19 10.8 5.7 0.29 10.2 4.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region YqfQ PF14181.1 ETO30404.1 - 1.2 9.1 6.7 2.4 8.1 4.6 1.4 1 0 0 1 1 1 0 YqfQ-like protein Glycos_transf_4 PF00953.16 ETO30405.1 - 1.9e-36 125.2 10.7 1.9e-36 125.2 7.4 2.5 4 0 0 4 4 4 1 Glycosyl transferase family 4 DUF2013 PF09431.5 ETO30406.1 - 2.5e-05 24.0 0.4 5.3e-05 23.0 0.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2013) Mito_carr PF00153.22 ETO30407.1 - 1.4e-28 98.4 0.0 4.3e-20 71.2 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein Metallophos PF00149.23 ETO30408.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Metallophos PF00149.23 ETO30409.1 - 3.6e-28 98.3 0.3 1.3e-27 96.5 0.0 2.1 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Kelch_4 PF13418.1 ETO30409.1 - 2.5e-13 49.5 0.5 0.00093 18.9 0.0 5.1 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO30409.1 - 9.6e-13 47.9 0.5 2.7e-08 33.7 0.0 5.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO30409.1 - 7.7e-09 35.3 0.0 0.11 12.4 0.0 4.8 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 ETO30409.1 - 3.8e-07 29.9 0.1 1.1 9.5 0.0 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 ETO30409.1 - 0.00084 18.8 0.0 0.45 10.1 0.0 3.6 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO30409.1 - 0.018 14.7 6.5 1.5 8.7 0.1 4.8 5 0 0 5 5 5 0 Kelch motif LOH1CR12 PF10158.4 ETO30410.1 - 0.047 13.4 5.7 0.98 9.2 0.7 2.5 2 1 0 2 2 2 0 Tumour suppressor protein TMV_coat PF00721.16 ETO30410.1 - 0.088 12.7 2.2 0.36 10.7 0.3 2.3 2 0 0 2 2 2 0 Virus coat protein (TMV like) DASH_Dad3 PF08656.5 ETO30410.1 - 0.49 10.1 3.8 1.5 8.5 0.2 2.6 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF4298 PF14131.1 ETO30410.1 - 0.98 9.3 0.0 0.98 9.3 0.0 3.6 3 2 2 5 5 5 0 Domain of unknown function (DUF4298) Apc15p PF05841.6 ETO30411.1 - 0.38 11.5 7.9 0.47 11.1 5.5 1.2 1 0 0 1 1 1 0 Apc15p protein RRS1 PF04939.7 ETO30412.1 - 0.081 12.3 5.0 0.25 10.8 3.4 1.9 1 1 0 1 1 1 0 Ribosome biogenesis regulatory protein (RRS1) DUF4517 PF15006.1 ETO30413.1 - 4.5e-11 42.8 0.8 1.6e-10 41.1 0.6 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4517) Spt5_N PF11942.3 ETO30413.1 - 0.0031 18.1 6.1 0.0031 18.1 4.2 2.9 3 0 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal DUF2556 PF10831.3 ETO30413.1 - 0.14 11.8 4.3 1.8 8.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2556) Ribosomal_60s PF00428.14 ETO30413.1 - 0.79 10.1 8.4 0.45 10.9 4.3 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein PBP1_TM PF14812.1 ETO30413.1 - 2 8.7 7.4 7.7 6.9 0.2 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.1 ETO30413.1 - 3.6 7.2 10.9 0.99 9.0 1.6 3.0 2 0 0 2 2 2 0 FAM176 family CoA_transf_3 PF02515.12 ETO30414.1 - 1.4e-47 161.3 0.0 6.6e-40 136.3 0.0 2.1 2 0 0 2 2 2 2 CoA-transferase family III DUF3399 PF11879.3 ETO30415.1 - 0.087 13.0 0.1 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3399) RhoGAP PF00620.22 ETO30416.1 - 1.2e-05 25.0 0.2 4.4e-05 23.1 0.1 2.0 1 1 0 1 1 1 1 RhoGAP domain MVIN PF03023.9 ETO30416.1 - 0.0098 14.3 0.6 0.0098 14.3 0.4 1.8 1 1 1 2 2 2 1 MviN-like protein Ammonium_transp PF00909.16 ETO30417.1 - 5.6e-18 64.5 1.1 6.4e-18 64.4 0.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Ammonium_transp PF00909.16 ETO30418.1 - 1.5e-24 86.1 9.0 7.9e-24 83.8 6.2 1.8 1 1 0 1 1 1 1 Ammonium Transporter Family Bac_Ubq_Cox PF01654.12 ETO30418.1 - 0.02 13.3 0.0 0.034 12.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial Cytochrome Ubiquinol Oxidase Peptidase_C36 PF05415.6 ETO30419.1 - 0.039 13.8 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 Beet necrotic yellow vein furovirus-type papain-like endopeptidase Pkinase PF00069.20 ETO30420.1 - 0.012 14.7 0.0 0.017 14.3 0.0 1.4 1 1 0 1 1 1 0 Protein kinase domain EI24 PF07264.6 ETO30420.1 - 0.055 12.8 0.8 0.086 12.2 0.6 1.3 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF3464 PF11947.3 ETO30420.1 - 0.31 10.4 1.5 2.5 7.5 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3464) PBP1_TM PF14812.1 ETO30420.1 - 2.9 8.2 12.9 6 7.2 8.9 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PP2C PF00481.16 ETO30421.1 - 6.6e-47 160.0 0.0 1.8e-42 145.5 0.0 2.1 1 1 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 ETO30421.1 - 0.0002 20.8 0.2 0.00054 19.4 0.1 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C pRN1_helical PF13010.1 ETO30421.1 - 0.13 11.9 0.0 0.89 9.1 0.0 2.0 2 0 0 2 2 2 0 Primase helical domain UPF0564 PF10595.4 ETO30422.1 - 0.037 12.9 22.5 0.045 12.6 15.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 DUF2489 PF10675.4 ETO30422.1 - 0.57 9.8 10.8 0.53 9.9 7.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2489) DUF2201_N PF13203.1 ETO30422.1 - 1.1 8.3 6.7 1.3 8.1 4.7 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain GAGA_bind PF06217.7 ETO30422.1 - 1.5 8.6 19.3 1.8 8.4 13.4 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2413 PF10310.4 ETO30422.1 - 1.8 7.2 14.7 2.1 7.0 10.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Spt5_N PF11942.3 ETO30422.1 - 7.3 7.2 13.4 10 6.8 9.3 1.4 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal PTPlike_phytase PF14566.1 ETO30423.1 - 1.5e-18 67.2 0.4 1.3e-17 64.2 0.3 2.7 1 1 0 1 1 1 1 Inositol hexakisphosphate HTH_39 PF14090.1 ETO30423.1 - 0.0058 16.0 0.0 0.018 14.4 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain DUF908 PF06012.7 ETO30424.1 - 0.035 13.4 6.7 0.047 12.9 4.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Macoilin PF09726.4 ETO30424.1 - 0.15 10.3 10.0 0.17 10.1 6.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Pox_Ag35 PF03286.9 ETO30424.1 - 0.23 10.9 15.3 0.39 10.2 10.6 1.6 1 1 0 1 1 1 0 Pox virus Ag35 surface protein POX PF07526.6 ETO30424.1 - 2 8.6 8.3 3.5 7.8 5.7 1.5 1 0 0 1 1 1 0 Associated with HOX MFMR PF07777.6 ETO30424.1 - 2 8.2 16.5 2.9 7.8 11.4 1.2 1 0 0 1 1 1 0 G-box binding protein MFMR DUF4175 PF13779.1 ETO30424.1 - 9.4 3.7 8.1 12 3.4 5.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Glyco_transf_92 PF01697.22 ETO30426.1 - 1.6e-10 40.7 9.1 2e-09 37.1 6.3 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.1 ETO30426.1 - 5.2e-06 26.6 4.5 3.4e-05 24.0 3.1 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 2 AP_endonuc_2 PF01261.19 ETO30427.1 - 0.084 12.1 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel SUV3_C PF12513.3 ETO30427.1 - 3.9 7.0 6.2 8.6 5.8 0.0 3.1 3 0 0 3 3 3 0 Mitochondrial degradasome RNA helicase subunit C terminal RRM_1 PF00076.17 ETO30428.1 - 1.8e-11 43.4 1.7 1e-05 25.0 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO30428.1 - 9.3e-11 41.5 0.4 2.9e-06 27.1 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO30428.1 - 0.0017 18.1 0.7 0.97 9.3 0.0 3.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4283 PF14111.1 ETO30428.1 - 0.016 14.2 0.0 0.057 12.4 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4283) Limkain-b1 PF11608.3 ETO30428.1 - 0.049 13.3 0.8 3.1 7.6 0.0 2.8 3 1 0 3 3 3 0 Limkain b1 Guanylate_cyc PF00211.15 ETO30429.1 - 4.5e-21 75.0 0.0 8.3e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Adaptin_binding PF10199.4 ETO30429.1 - 0.00011 22.5 4.3 0.00011 22.5 3.0 3.3 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 Spt5_N PF11942.3 ETO30429.1 - 0.0047 17.5 14.6 0.0047 17.5 10.1 3.0 3 0 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal Sigma70_ner PF04546.8 ETO30429.1 - 0.0089 15.6 19.2 0.0089 15.6 13.3 2.5 2 1 0 2 2 2 1 Sigma-70, non-essential region DUF2031 PF09592.5 ETO30430.1 - 0.002 17.3 11.3 0.0021 17.2 7.1 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF2031) Ly49 PF08391.5 ETO30430.1 - 0.0025 17.9 1.1 0.0025 17.9 0.8 2.7 2 1 0 2 2 1 1 Ly49-like protein, N-terminal region Imm6 PF14434.1 ETO30430.1 - 0.0028 17.3 1.0 0.0048 16.6 0.3 1.6 1 1 0 1 1 1 1 Immunity protein Imm6 Phasin PF05597.6 ETO30430.1 - 0.0043 16.8 9.8 0.0064 16.2 6.8 1.2 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) PP2C_C PF07830.8 ETO30430.1 - 0.027 14.5 1.7 0.064 13.3 1.2 1.8 1 1 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain MIS13 PF08202.6 ETO30430.1 - 0.065 12.3 10.3 0.081 11.9 7.1 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family FliT PF05400.8 ETO30430.1 - 0.13 12.7 12.3 0.74 10.2 8.0 2.0 1 1 1 2 2 2 0 Flagellar protein FliT CALCOCO1 PF07888.6 ETO30430.1 - 0.22 9.7 7.6 0.26 9.5 5.2 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like TMP_2 PF06791.8 ETO30430.1 - 0.25 10.9 2.7 0.37 10.3 1.9 1.3 1 0 0 1 1 1 0 Prophage tail length tape measure protein DUF342 PF03961.8 ETO30430.1 - 0.25 9.6 12.9 0.32 9.3 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Exonuc_VII_L PF02601.10 ETO30430.1 - 0.35 10.0 5.4 0.36 9.9 3.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit AbiH PF14253.1 ETO30430.1 - 0.44 10.0 6.8 0.59 9.6 4.7 1.1 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH CDC45 PF02724.9 ETO30430.1 - 0.6 8.0 5.5 0.7 7.8 3.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Cep57_MT_bd PF06657.8 ETO30430.1 - 0.64 10.0 12.2 0.38 10.7 1.4 2.3 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DivIVA PF05103.8 ETO30430.1 - 0.8 9.7 16.4 1.1 9.2 11.3 1.2 1 0 0 1 1 1 0 DivIVA protein AAA_11 PF13086.1 ETO30430.1 - 0.81 9.2 5.8 1.1 8.7 4.0 1.2 1 0 0 1 1 1 0 AAA domain Med17 PF10156.4 ETO30430.1 - 1.1 7.4 9.8 1.4 7.1 6.8 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex DUF1525 PF07511.6 ETO30430.1 - 2.4 8.1 4.5 2.6 8.0 2.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1525) Takusan PF04822.8 ETO30430.1 - 5.3 6.8 15.5 0.11 12.2 3.7 2.5 1 1 1 2 2 2 0 Takusan DUF4164 PF13747.1 ETO30430.1 - 5.5 7.2 13.6 3.9 7.6 2.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DUF607 PF04678.8 ETO30430.1 - 5.6 6.8 7.4 11 5.9 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF607 TPD52 PF04201.10 ETO30430.1 - 7.9 6.1 12.4 12 5.6 8.6 1.4 1 1 0 1 1 1 0 Tumour protein D52 family TraX PF05857.6 ETO30431.1 - 0.054 13.1 0.4 0.071 12.7 0.3 1.1 1 0 0 1 1 1 0 TraX protein Cytochrom_B_N PF00033.14 ETO30432.1 - 0.0023 17.3 1.7 0.0023 17.3 1.2 1.5 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB OPT PF03169.10 ETO30432.1 - 0.0068 14.8 5.8 0.0086 14.5 4.1 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein 7TMR-DISM_7TM PF07695.6 ETO30432.1 - 0.036 13.7 11.6 0.11 12.1 8.0 1.7 1 1 0 1 1 1 0 7TM diverse intracellular signalling Ni_hydr_CYTB PF01292.15 ETO30432.1 - 0.12 11.7 5.5 0.25 10.7 1.4 2.0 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 PepSY_TM PF03929.11 ETO30432.1 - 1.1 9.7 9.0 1.1 9.7 0.0 3.3 3 0 0 3 3 3 0 PepSY-associated TM helix 2TM PF13239.1 ETO30432.1 - 6.4 6.9 6.8 6 6.9 2.3 2.3 2 0 0 2 2 2 0 2TM domain ADH_zinc_N PF00107.21 ETO30433.1 - 1.6e-23 82.6 0.0 2.5e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETO30433.1 - 5.6e-17 62.8 0.0 1.2e-16 61.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETO30433.1 - 1.7e-09 37.4 0.0 2.9e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain EutA PF06277.6 ETO30433.1 - 0.044 12.3 0.1 0.073 11.6 0.1 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutA WD40 PF00400.27 ETO30434.1 - 5.9e-68 222.5 10.9 6.3e-15 54.3 0.2 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat PQQ_2 PF13360.1 ETO30434.1 - 2.2e-11 43.6 1.2 0.00011 21.7 0.2 2.3 1 1 1 2 2 2 2 PQQ-like domain Nup160 PF11715.3 ETO30434.1 - 4.9e-09 34.8 0.9 0.018 13.2 0.0 3.5 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Gmad1 PF10647.4 ETO30434.1 - 3.3e-07 29.9 0.4 0.00014 21.3 0.1 2.7 1 1 1 3 3 3 2 Lipoprotein LpqB beta-propeller domain Cytochrom_D1 PF02239.11 ETO30434.1 - 1.1e-05 23.8 2.6 0.024 12.9 0.1 3.1 1 1 2 3 3 3 3 Cytochrome D1 heme domain PD40 PF07676.7 ETO30434.1 - 0.00014 21.4 3.7 10 5.8 0.0 4.5 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Me-amine-dh_H PF06433.6 ETO30434.1 - 0.0009 17.9 0.0 0.15 10.7 0.0 2.3 1 1 0 2 2 2 2 Methylamine dehydrogenase heavy chain (MADH) DUF4221 PF13970.1 ETO30434.1 - 0.0038 16.5 0.5 0.9 8.7 0.0 2.6 1 1 2 3 3 3 2 Domain of unknown function (DUF4221) AcetylCoA_hyd_C PF13336.1 ETO30434.1 - 0.0085 15.7 3.1 7 6.2 0.1 4.1 4 1 1 5 5 5 1 Acetyl-CoA hydrolase/transferase C-terminal domain Proteasome_A_N PF10584.4 ETO30434.1 - 0.016 14.5 8.7 25 4.2 0.1 5.2 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature PQQ_3 PF13570.1 ETO30434.1 - 0.026 14.7 0.0 64 4.0 0.0 4.0 4 0 0 4 4 4 0 PQQ-like domain DUF1258 PF06869.7 ETO30434.1 - 0.044 12.8 0.0 3.2 6.7 0.0 3.0 1 1 3 4 4 4 0 Protein of unknown function (DUF1258) NYD-SP28_assoc PF14775.1 ETO30434.1 - 0.049 13.3 0.0 72 3.1 0.0 3.8 4 0 0 4 4 4 0 Sperm tail C-terminal domain KSR1-SAM PF13543.1 ETO30436.1 - 0.012 15.4 0.1 0.022 14.5 0.1 1.4 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 EcoR124_C PF12008.3 ETO30436.1 - 0.013 14.7 0.9 0.017 14.3 0.6 1.1 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal PP1_inhibitor PF05361.7 ETO30436.1 - 0.08 12.6 0.3 0.11 12.1 0.2 1.3 1 0 0 1 1 1 0 PKC-activated protein phosphatase-1 inhibitor SAM_1 PF00536.25 ETO30437.1 - 1.6e-08 34.5 0.0 3e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO30437.1 - 0.00096 18.9 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ste50p-SAM PF09235.5 ETO30437.1 - 0.062 13.3 0.1 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 Ste50p, sterile alpha motif SH3_1 PF00018.23 ETO30437.1 - 0.11 11.8 2.2 4.3 6.8 0.0 2.5 1 1 1 2 2 2 0 SH3 domain Ashwin PF15323.1 ETO30438.1 - 0.02 14.8 0.6 0.024 14.6 0.4 1.0 1 0 0 1 1 1 0 Developmental protein FAM176 PF14851.1 ETO30438.1 - 0.034 13.8 0.6 0.048 13.3 0.4 1.3 1 0 0 1 1 1 0 FAM176 family Vpu PF00558.14 ETO30438.1 - 0.27 10.7 0.9 0.51 9.9 0.6 1.4 1 0 0 1 1 1 0 Vpu protein BORG_CEP PF14957.1 ETO30438.1 - 0.34 11.8 6.1 6.3 7.7 0.3 2.3 2 1 0 2 2 2 0 Cdc42 effector Tom22 PF04281.8 ETO30438.1 - 1.4 8.4 5.4 2.2 7.8 3.7 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 PIG-S PF10510.4 ETO30439.1 - 0.015 14.0 0.2 0.016 13.8 0.1 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein DSHCT PF08148.7 ETO30439.1 - 0.068 12.4 0.2 0.12 11.6 0.2 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain DUF4347 PF14252.1 ETO30439.1 - 0.079 12.4 0.1 0.13 11.7 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4347) CHASE3 PF05227.8 ETO30439.1 - 0.15 11.7 0.9 0.35 10.5 0.5 1.6 1 1 1 2 2 2 0 CHASE3 domain DUF3891 PF13030.1 ETO30439.1 - 0.17 11.3 2.7 0.43 10.0 1.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3891) Zip PF02535.17 ETO30440.1 - 0.00056 19.0 4.3 0.04 12.9 0.0 3.1 4 0 0 4 4 4 2 ZIP Zinc transporter OATP PF03137.15 ETO30440.1 - 0.0016 16.6 0.1 0.0016 16.6 0.1 3.5 3 1 1 4 4 4 1 Organic Anion Transporter Polypeptide (OATP) family TMEMspv1-c74-12 PF11044.3 ETO30440.1 - 0.0062 16.0 0.6 0.33 10.5 0.0 2.9 2 0 0 2 2 2 1 Plectrovirus spv1-c74 ORF 12 transmembrane protein Neur_chan_memb PF02932.11 ETO30440.1 - 0.01 15.7 2.9 0.01 15.7 2.0 2.7 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF4381 PF14316.1 ETO30440.1 - 0.016 15.3 0.0 0.016 15.3 0.0 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF4381) PIG-P PF08510.7 ETO30440.1 - 0.035 13.7 8.6 0.49 10.0 0.0 4.0 3 1 0 4 4 4 0 PIG-P COX16 PF14138.1 ETO30440.1 - 0.96 9.6 6.9 0.33 11.1 0.4 2.6 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Peroxin-13_N PF04088.8 ETO30440.1 - 1 9.3 9.3 0.57 10.1 0.2 3.4 3 0 0 3 3 3 0 Peroxin 13, N-terminal region PBP1_TM PF14812.1 ETO30440.1 - 2.6 8.4 0.0 2.6 8.4 0.0 4.1 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SAM_2 PF07647.12 ETO30441.1 - 3.8e-08 33.0 0.0 7.6e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO30441.1 - 1.6e-06 28.1 0.0 3.7e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF2681 PF10883.3 ETO30441.1 - 0.035 14.3 4.1 0.29 11.3 2.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF4407 PF14362.1 ETO30441.1 - 2.1 7.2 5.3 4.7 6.0 3.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_1 PF00170.16 ETO30441.1 - 5.8 6.9 15.1 1.5 8.8 6.5 2.8 2 0 0 2 2 2 0 bZIP transcription factor HD PF01966.17 ETO30442.1 - 1.1e-06 28.6 0.9 2e-06 27.8 0.6 1.4 1 0 0 1 1 1 1 HD domain DUF4473 PF14747.1 ETO30442.1 - 0.023 14.8 0.3 0.023 14.8 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) ABC_tran_2 PF12848.2 ETO30442.1 - 0.14 11.9 4.5 0.094 12.5 0.7 2.2 2 0 0 2 2 2 0 ABC transporter DUF2804 PF10974.3 ETO30444.1 - 0.018 13.9 0.8 0.019 13.8 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2804) Pkinase PF00069.20 ETO30445.1 - 4.7e-71 238.9 0.0 8.8e-71 238.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO30445.1 - 3.5e-38 131.1 0.1 4.6e-37 127.4 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 ETO30445.1 - 5.4e-22 77.5 0.7 5.5e-11 42.2 0.0 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 ETO30445.1 - 5.2e-05 22.3 0.0 0.16 10.8 0.0 2.8 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 ETO30445.1 - 0.0044 16.7 0.2 0.037 13.7 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RRM_1 PF00076.17 ETO30447.1 - 1.5e-17 62.9 0.0 3.2e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO30447.1 - 3.3e-13 49.4 0.0 7.2e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO30447.1 - 5.9e-13 48.4 0.0 1.7e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2262 PF10020.4 ETO30448.1 - 0.0064 16.7 1.0 0.01 16.0 0.7 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2262) HypA PF01155.14 ETO30449.1 - 0.0014 18.2 1.3 0.0027 17.3 0.7 1.6 2 0 0 2 2 2 1 Hydrogenase expression/synthesis hypA family TF_Zn_Ribbon PF08271.7 ETO30449.1 - 0.0044 16.3 0.2 0.0044 16.3 0.1 2.8 4 1 0 4 4 4 1 TFIIB zinc-binding Prok-RING_1 PF14446.1 ETO30449.1 - 0.78 9.5 7.9 0.15 11.8 2.0 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF678 PF05077.7 ETO30449.1 - 0.81 9.7 3.5 4.4 7.3 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF678) zf-UBR PF02207.15 ETO30449.1 - 0.97 9.1 7.0 10 5.8 3.7 3.0 2 1 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) zf-C3HC4_3 PF13920.1 ETO30449.1 - 1.9 8.1 7.4 4.4 7.0 2.1 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C4_Topoisom PF01396.14 ETO30449.1 - 5.2 6.6 7.0 1.1 8.8 0.1 2.7 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_2 PF13240.1 ETO30449.1 - 6.7 6.3 9.6 0.28 10.7 0.7 2.8 3 0 0 3 3 3 0 zinc-ribbon domain Lipase_3 PF01764.20 ETO30451.1 - 0.032 13.8 0.0 0.066 12.8 0.0 1.6 1 1 0 1 1 1 0 Lipase (class 3) Ycf1 PF05758.7 ETO30454.1 - 0.15 9.7 23.8 0.33 8.6 9.0 2.4 2 0 0 2 2 2 0 Ycf1 ETRAMP PF09716.5 ETO30454.1 - 0.21 11.5 5.3 5.7 6.9 0.0 4.5 4 2 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) Mitofilin PF09731.4 ETO30454.1 - 0.57 8.7 32.1 0.036 12.7 11.6 2.2 2 0 0 2 2 2 0 Mitochondrial inner membrane protein Atrophin-1 PF03154.10 ETO30454.1 - 1.2 7.1 22.1 0.39 8.8 4.6 2.4 2 0 0 2 2 2 0 Atrophin-1 family Shisa PF13908.1 ETO30454.1 - 4.4 7.4 8.3 1.7 8.7 0.2 3.2 3 1 1 4 4 4 0 Wnt and FGF inhibitory regulator Ribosomal_60s PF00428.14 ETO30454.1 - 4.7 7.6 16.2 0.39 11.1 0.1 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Motile_Sperm PF00635.21 ETO30455.1 - 2e-05 24.1 8.3 0.11 12.1 0.0 4.9 5 0 0 5 5 5 2 MSP (Major sperm protein) domain Motile_Sperm PF00635.21 ETO30456.1 - 0.039 13.5 5.5 0.71 9.5 0.1 3.8 3 0 0 3 3 3 0 MSP (Major sperm protein) domain PapD-like PF14874.1 ETO30456.1 - 0.11 12.4 0.2 9.2 6.2 0.1 2.9 3 0 0 3 3 3 0 Flagellar-associated PapD-like DUF1129 PF06570.6 ETO30457.1 - 0.056 12.7 2.2 0.088 12.1 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF2392 PF10288.4 ETO30458.1 - 0.14 12.4 0.9 0.37 11.1 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2392) PAE PF03283.8 ETO30460.1 - 6.1e-08 31.6 3.1 6.1e-08 31.6 2.2 1.6 1 1 1 2 2 2 1 Pectinacetylesterase TPR_12 PF13424.1 ETO30461.1 - 1.4e-29 101.7 2.2 9e-14 51.1 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO30461.1 - 7.9e-23 79.8 6.2 1.5e-11 43.8 0.8 2.5 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETO30461.1 - 5.6e-20 70.0 12.6 2.1e-08 33.4 0.5 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO30461.1 - 1.3e-16 59.0 10.1 6e-06 25.7 0.3 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO30461.1 - 3.2e-15 54.6 2.1 9.7e-06 25.0 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO30461.1 - 2.3e-12 46.4 0.0 4.7e-08 32.7 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO30461.1 - 1.8e-10 39.7 14.9 1.6e-06 27.4 1.9 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO30461.1 - 1.2e-09 37.6 0.3 0.0019 18.2 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO30461.1 - 1.5e-06 28.6 2.0 0.00073 20.1 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat MIT PF04212.13 ETO30461.1 - 0.00029 20.6 3.5 0.3 10.9 0.2 4.2 2 1 1 3 3 3 1 MIT (microtubule interacting and transport) domain PPR PF01535.15 ETO30461.1 - 0.004 17.0 0.8 0.071 13.1 0.0 3.3 2 0 0 2 2 2 1 PPR repeat TPR_14 PF13428.1 ETO30461.1 - 0.0095 16.5 0.0 9.4 7.1 0.0 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO30461.1 - 0.012 15.7 3.5 0.27 11.4 0.5 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETO30461.1 - 0.074 13.5 5.3 0.12 12.8 0.1 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_3 PF07720.7 ETO30461.1 - 3.2 7.6 8.9 0.69 9.7 1.4 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat zf-C2H2_4 PF13894.1 ETO30463.1 - 5.3e-08 32.6 57.6 0.0015 18.7 2.3 7.8 7 1 0 7 7 7 4 C2H2-type zinc finger zf-C2H2 PF00096.21 ETO30463.1 - 2.1e-07 30.8 52.5 0.00092 19.4 0.7 7.4 7 0 0 7 7 7 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETO30463.1 - 9e-07 28.8 38.0 0.034 14.4 2.3 7.2 7 0 0 7 7 7 5 Zinc-finger double domain zf-met PF12874.2 ETO30463.1 - 0.0024 18.0 30.0 0.013 15.7 1.0 6.7 7 0 0 7 7 7 3 Zinc-finger of C2H2 type GAGA PF09237.6 ETO30463.1 - 0.065 12.8 7.8 0.33 10.5 0.1 3.0 3 0 0 3 3 3 0 GAGA factor zf-C2H2_jaz PF12171.3 ETO30463.1 - 0.094 12.8 32.7 0.4 10.8 1.5 6.5 6 1 0 6 6 6 0 Zinc-finger double-stranded RNA-binding C2 PF00168.25 ETO30464.1 - 1.5e-11 43.9 0.9 1.1e-08 34.8 0.0 3.0 3 1 0 3 3 3 2 C2 domain DUF4044 PF13253.1 ETO30464.1 - 0.92 8.7 4.1 20 4.4 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4044) MAT1 PF06391.8 ETO30466.1 - 3.2e-09 36.6 7.1 6.6e-09 35.6 4.9 1.5 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 Baculo_IE-1 PF05290.6 ETO30466.1 - 0.0018 18.0 4.4 0.0047 16.6 3.1 1.7 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) SPOR PF05036.8 ETO30466.1 - 0.056 13.6 0.1 2.2 8.4 0.0 2.4 1 1 1 2 2 2 0 Sporulation related domain DUF724 PF05266.9 ETO30466.1 - 0.064 12.8 3.8 0.13 11.8 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) zf-C3HC4_3 PF13920.1 ETO30466.1 - 1.5 8.5 9.8 12 5.6 6.8 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PaaSYMP PF14738.1 ETO30467.1 - 2.6e-15 56.4 14.7 2.6e-15 56.4 10.2 2.3 3 0 0 3 3 3 1 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 Hexose_dehydrat PF03559.9 ETO30467.1 - 0.012 14.6 0.7 0.026 13.5 0.5 1.5 1 0 0 1 1 1 0 NDP-hexose 2,3-dehydratase Paxillin PF03535.8 ETO30467.1 - 0.13 12.1 3.0 0.21 11.3 2.1 1.4 1 0 0 1 1 1 0 Paxillin family KMP11 PF03037.11 ETO30467.1 - 5 7.7 11.4 7.5 7.2 1.3 3.1 3 0 0 3 3 3 0 Kinetoplastid membrane protein 11 Asp PF00026.18 ETO30468.1 - 9.8e-38 130.1 1.7 1.4e-37 129.6 1.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETO30468.1 - 7.9e-06 25.9 4.6 3.5e-05 23.8 3.2 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal S_locus_glycop PF00954.15 ETO30468.1 - 0.0013 18.9 2.0 0.0028 17.9 1.4 1.5 1 0 0 1 1 1 1 S-locus glycoprotein family zf-C2H2 PF00096.21 ETO30469.1 - 0.0056 16.9 0.1 0.0056 16.9 0.1 3.1 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETO30469.1 - 0.29 11.5 5.4 0.41 11.0 0.8 2.8 2 0 0 2 2 2 0 Zinc-finger double domain DUF2269 PF10027.4 ETO30470.1 - 0.0025 17.6 1.2 0.0042 16.8 0.9 1.3 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2269) Ist1 PF03398.9 ETO30471.1 - 2.9e-06 26.8 0.7 5.6e-06 25.8 0.5 1.5 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Daxx PF03344.10 ETO30473.1 - 0.0011 17.5 28.9 0.0014 17.2 20.0 1.2 1 0 0 1 1 1 1 Daxx Family Utp14 PF04615.8 ETO30473.1 - 0.19 9.8 33.8 0.27 9.3 23.4 1.2 1 0 0 1 1 1 0 Utp14 protein Nucleoplasmin PF03066.10 ETO30473.1 - 2.9 7.3 16.9 0.03 13.8 4.7 2.5 2 0 0 2 2 2 0 Nucleoplasmin WD40 PF00400.27 ETO30474.1 - 9e-34 114.1 1.2 3e-11 42.7 0.1 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO30474.1 - 0.00011 20.4 0.1 0.26 9.3 0.0 2.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO30474.1 - 0.00019 21.2 0.0 0.00052 19.7 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO30474.1 - 0.00049 19.6 0.1 3.5 7.3 0.0 3.2 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO30474.1 - 0.0034 16.2 0.4 0.28 9.8 0.0 2.2 1 1 1 2 2 2 2 Nup133 N terminal like PQQ_2 PF13360.1 ETO30474.1 - 0.0045 16.4 0.0 0.092 12.1 0.0 2.1 1 1 1 2 2 2 2 PQQ-like domain Coatomer_WDAD PF04053.9 ETO30474.1 - 0.018 13.8 0.1 0.023 13.4 0.1 1.2 1 0 0 1 1 1 0 Coatomer WD associated region Proteasome_A_N PF10584.4 ETO30474.1 - 0.034 13.4 0.3 8.9 5.7 0.0 3.2 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Nbas_N PF15492.1 ETO30474.1 - 0.066 12.3 0.4 12 4.9 0.0 2.6 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Resistin PF06954.6 ETO30474.1 - 0.15 12.3 0.0 16 5.8 0.0 2.7 1 1 2 3 3 3 0 Resistin WD40 PF00400.27 ETO30476.1 - 9e-57 187.0 4.3 2.7e-13 49.2 0.0 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO30476.1 - 2.4e-06 25.9 1.9 0.016 13.3 0.0 3.8 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO30476.1 - 3.8e-06 25.4 0.3 0.001 17.4 0.1 2.2 1 1 1 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.7 ETO30476.1 - 7.8e-06 25.4 2.1 1.8 8.2 0.1 4.7 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO30476.1 - 0.00053 18.8 4.2 0.6 8.7 0.1 3.6 1 1 2 4 4 4 3 Nup133 N terminal like Resistin PF06954.6 ETO30476.1 - 0.00066 19.8 0.0 7.1 6.9 0.0 4.3 2 2 3 5 5 5 1 Resistin Nbas_N PF15492.1 ETO30476.1 - 0.001 18.2 0.1 0.54 9.3 0.0 2.9 1 1 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal HARP PF07443.8 ETO30476.1 - 0.016 14.5 0.0 6 6.3 0.0 2.7 2 0 0 2 2 2 0 HepA-related protein (HARP) Proteasome_A_N PF10584.4 ETO30476.1 - 0.026 13.8 0.4 3.5 7.0 0.0 3.3 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature DUF1797 PF08796.5 ETO30476.1 - 0.028 14.2 0.0 12 5.8 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1797) DPPIV_N PF00930.16 ETO30476.1 - 0.05 12.1 0.1 0.44 9.0 0.0 2.2 1 1 2 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PQQ_2 PF13360.1 ETO30476.1 - 0.075 12.4 0.1 0.3 10.4 0.1 1.8 1 1 0 1 1 1 0 PQQ-like domain DIOX_N PF14226.1 ETO30477.1 - 2.7e-23 82.6 0.1 4.2e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETO30477.1 - 8.9e-21 74.0 0.1 1.8e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LKAAEAR PF15478.1 ETO30477.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function with LKAAEAR motif L71 PF02448.10 ETO30478.1 - 0.018 14.8 12.5 0.6 9.9 5.1 2.4 2 0 0 2 2 2 0 L71 family Ion_trans PF00520.26 ETO30479.1 - 1.4e-07 31.0 2.7 2.7e-07 30.0 1.9 1.5 1 0 0 1 1 1 1 Ion transport protein Ion_trans_N PF08412.5 ETO30479.1 - 3e-05 23.2 0.7 6.6e-05 22.1 0.5 1.5 1 0 0 1 1 1 1 Ion transport protein N-terminal BTB PF00651.26 ETO30480.1 - 9.3e-19 67.4 2.2 7e-16 58.2 0.3 2.3 1 1 1 2 2 2 2 BTB/POZ domain phage_tail_N PF08400.5 ETO30480.1 - 0.042 13.5 0.0 0.093 12.4 0.0 1.6 1 1 0 1 1 1 0 Prophage tail fibre N-terminal CobT PF06213.7 ETO30481.1 - 0.0095 15.0 3.8 0.011 14.8 2.6 1.1 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Pox_Ag35 PF03286.9 ETO30481.1 - 0.015 14.8 9.3 0.019 14.5 6.4 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Borrelia_orfA PF02414.10 ETO30481.1 - 0.027 13.6 19.3 0.035 13.2 13.4 1.2 1 0 0 1 1 1 0 Borrelia ORF-A DUF4220 PF13968.1 ETO30481.1 - 0.16 11.0 2.5 0.18 10.8 1.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Menin PF05053.8 ETO30481.1 - 0.31 9.1 7.7 0.38 8.8 5.4 1.0 1 0 0 1 1 1 0 Menin Nop25 PF09805.4 ETO30481.1 - 0.5 10.4 7.8 0.63 10.1 5.4 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) GCD14 PF08704.5 ETO30481.1 - 0.6 9.5 2.7 0.77 9.2 1.8 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DUF3449 PF11931.3 ETO30481.1 - 0.67 9.4 7.9 0.86 9.0 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) DUF2457 PF10446.4 ETO30481.1 - 0.82 8.3 10.6 1 8.0 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FAM176 PF14851.1 ETO30481.1 - 2.7 7.6 6.1 6.9 6.3 4.4 1.4 1 1 0 1 1 1 0 FAM176 family Eapp_C PF10238.4 ETO30481.1 - 3.1 7.6 15.2 5 7.0 10.5 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein RCC1_2 PF13540.1 ETO30482.1 - 5e-09 35.5 3.8 0.00011 21.6 0.2 2.5 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 ETO30482.1 - 0.0006 19.9 0.7 0.0096 16.1 0.0 3.0 3 1 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 ETO30482.1 - 0.15 11.5 0.2 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Putative carbohydrate binding domain RCC1 PF00415.13 ETO30483.1 - 9.5e-13 48.1 7.9 0.00019 21.5 0.0 4.6 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO30483.1 - 3.7e-12 45.5 8.0 2.1e-06 27.1 2.2 3.0 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Methyltransf_12 PF08242.7 ETO30483.1 - 0.02 15.3 0.5 0.054 13.9 0.3 1.8 1 0 0 1 1 1 0 Methyltransferase domain Spore_coat_CotO PF14153.1 ETO30483.1 - 0.24 10.8 12.5 0.47 9.8 8.7 1.4 1 0 0 1 1 1 0 Spore coat protein CotO MMR1 PF08505.5 ETO30483.1 - 0.52 10.3 14.0 0.027 14.4 5.9 1.6 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Tim54 PF11711.3 ETO30483.1 - 1.1 7.7 9.6 1.8 7.0 6.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Pox_RNA_Pol_19 PF05320.7 ETO30483.1 - 5.3 6.7 12.2 4.5 6.9 5.9 2.2 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit SAM_1 PF00536.25 ETO30484.1 - 1.6e-08 34.6 0.3 3.6e-08 33.4 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) MazG PF03819.12 ETO30484.1 - 1e-07 31.8 0.1 2.4e-07 30.6 0.1 1.7 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain SAM_2 PF07647.12 ETO30484.1 - 1.8e-05 24.5 0.2 5.2e-05 23.0 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ste50p-SAM PF09235.5 ETO30484.1 - 0.032 14.2 0.6 0.069 13.1 0.0 1.8 2 0 0 2 2 2 0 Ste50p, sterile alpha motif Lumazine_bd PF12870.2 ETO30484.1 - 0.081 12.9 1.5 0.12 12.4 0.1 2.0 2 0 0 2 2 2 0 Lumazine-binding domain DUF3674 PF12426.3 ETO30484.1 - 0.11 11.9 0.4 0.24 10.8 0.3 1.5 1 0 0 1 1 1 0 RNA dependent RNA polymerase DUF4328 PF14219.1 ETO30485.1 - 0.045 13.0 0.1 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) PepSY_TM_2 PF13703.1 ETO30485.1 - 0.08 13.1 0.5 0.16 12.1 0.4 1.5 1 0 0 1 1 1 0 PepSY-associated TM helix Ribosomal_L24e PF01246.15 ETO30486.1 - 5.7e-13 48.5 1.3 5.7e-13 48.5 0.9 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e CAGE1 PF15066.1 ETO30487.1 - 2.8e-06 26.0 5.7 3.2e-06 25.8 4.0 1.1 1 0 0 1 1 1 1 Cancer-associated gene protein 1 family V_ATPase_I PF01496.14 ETO30487.1 - 0.0099 13.7 3.1 0.012 13.5 2.1 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CorA PF01544.13 ETO30487.1 - 0.01 14.9 3.5 0.026 13.5 2.5 1.6 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Sds3 PF08598.6 ETO30487.1 - 0.014 14.8 3.8 0.12 11.9 2.6 2.0 1 1 0 1 1 1 0 Sds3-like Remorin_C PF03763.8 ETO30487.1 - 0.023 14.2 1.8 0.065 12.7 1.2 1.8 1 1 1 2 2 2 0 Remorin, C-terminal region Raptor_N PF14538.1 ETO30487.1 - 0.085 12.6 0.4 0.14 11.9 0.3 1.4 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain CDC37_N PF03234.9 ETO30487.1 - 0.1 12.8 2.3 0.18 12.1 1.6 1.4 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Dna2 PF08696.6 ETO30487.1 - 0.13 11.5 2.7 0.26 10.5 1.8 1.5 1 1 0 1 1 1 0 DNA replication factor Dna2 GAS PF13851.1 ETO30487.1 - 0.16 11.1 10.1 0.39 9.8 5.7 2.2 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.6 ETO30487.1 - 0.17 11.6 9.1 0.25 11.1 6.3 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Laminin_II PF06009.7 ETO30487.1 - 0.22 11.2 1.6 0.35 10.6 0.4 1.8 2 0 0 2 2 2 0 Laminin Domain II Clr5 PF14420.1 ETO30487.1 - 0.44 10.4 3.8 1.7 8.6 1.7 2.2 1 1 1 2 2 2 0 Clr5 domain Syntaxin PF00804.20 ETO30487.1 - 1.3 9.1 5.6 0.41 10.8 1.9 1.7 2 0 0 2 2 2 0 Syntaxin Pepsin-I3 PF06394.8 ETO30487.1 - 2.6 7.7 5.4 1 9.0 1.7 1.8 1 1 1 2 2 2 0 Pepsin inhibitor-3-like repeated domain DUF2570 PF10828.3 ETO30487.1 - 2.7 7.6 9.2 0.24 11.0 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) BTB PF00651.26 ETO30488.1 - 0.075 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 BTB/POZ domain Phlebovirus_NSM PF07246.6 ETO30489.1 - 0.02 14.0 0.2 0.026 13.6 0.2 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Lipase3_N PF03893.11 ETO30489.1 - 0.067 13.0 0.5 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Lipase 3 N-terminal region cNMP_binding PF00027.24 ETO30490.1 - 1.6e-06 27.8 0.0 2.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.26 ETO30490.1 - 0.00089 18.5 0.7 0.0014 17.9 0.5 1.3 1 0 0 1 1 1 1 Ion transport protein LRRNT_2 PF08263.7 ETO30490.1 - 0.078 12.9 1.3 0.19 11.6 0.9 1.6 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Ion_trans_2 PF07885.11 ETO30490.1 - 0.54 10.0 6.3 0.086 12.5 1.6 1.7 2 0 0 2 2 2 0 Ion channel DUF4131 PF13567.1 ETO30492.1 - 0.0036 16.7 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) DUF4094 PF13334.1 ETO30492.1 - 0.35 11.2 2.6 0.64 10.4 1.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) RloB PF13707.1 ETO30492.1 - 0.63 9.6 8.2 0.76 9.4 5.7 1.1 1 0 0 1 1 1 0 RloB-like protein RIO1 PF01163.17 ETO30493.1 - 5.7e-43 146.4 0.2 5.7e-43 146.4 0.2 2.4 2 1 0 2 2 2 1 RIO1 family Rio2_N PF09202.6 ETO30493.1 - 3.1e-22 78.4 1.1 3.3e-21 75.1 0.3 2.9 2 1 0 2 2 2 1 Rio2, N-terminal APH PF01636.18 ETO30493.1 - 2e-07 30.9 0.4 0.0064 16.2 0.3 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family PIP49_C PF12260.3 ETO30493.1 - 0.013 14.8 0.2 0.013 14.8 0.1 2.0 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 Laminin_II PF06009.7 ETO30494.1 - 0.0053 16.5 10.3 0.0053 16.5 7.2 2.7 1 1 2 3 3 3 1 Laminin Domain II WXG100 PF06013.7 ETO30494.1 - 0.7 9.9 12.2 0.78 9.7 2.1 3.3 2 1 1 3 3 3 0 Proteins of 100 residues with WXG TMF_TATA_bd PF12325.3 ETO30494.1 - 0.91 9.2 31.7 3 7.6 13.0 3.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF812 PF05667.6 ETO30494.1 - 1.1 7.6 29.6 0.24 9.8 10.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF812) FlaC_arch PF05377.6 ETO30494.1 - 1.7 8.6 15.7 1.4 8.9 2.0 4.3 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) CENP-F_leu_zip PF10473.4 ETO30494.1 - 4.2 7.2 30.0 21 4.9 7.6 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.17 ETO30494.1 - 4.3 7.3 26.9 8 6.5 6.5 3.8 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain ADIP PF11559.3 ETO30494.1 - 6.3 6.6 33.0 18 5.2 6.0 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 ETO30494.1 - 9.7 5.1 35.0 11 4.8 15.6 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 CBFD_NFYB_HMF PF00808.18 ETO30496.1 - 2.3e-12 46.7 0.2 1.8e-11 43.8 0.0 2.1 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Kelch_5 PF13854.1 ETO30497.1 - 0.053 13.4 0.0 8.3 6.4 0.0 2.4 2 0 0 2 2 2 0 Kelch motif Pkinase PF00069.20 ETO30498.1 - 2.9e-32 111.8 0.0 1.8e-27 96.1 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO30498.1 - 2e-28 99.2 0.1 9.3e-28 97.0 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 ETO30498.1 - 0.052 12.6 0.0 0.089 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3267 PF11667.3 ETO30499.1 - 0.44 10.7 2.4 0.33 11.1 0.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3267) Methylase_S PF01420.14 ETO30499.1 - 0.76 9.7 12.5 1.5 8.7 8.6 1.6 1 1 0 1 1 1 0 Type I restriction modification DNA specificity domain ArfGap PF01412.13 ETO30500.1 - 1.1e-30 105.7 0.7 3.5e-30 104.1 0.1 1.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf zf-DNL PF05180.7 ETO30500.1 - 0.073 12.7 0.6 0.17 11.6 0.4 1.5 1 0 0 1 1 1 0 DNL zinc finger Glyco_hydro_47 PF01532.15 ETO30502.1 - 2.8e-65 220.7 0.4 3.1e-65 220.5 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1724 PF08350.5 ETO30502.1 - 0.023 14.2 0.1 0.79 9.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1724) Glyco_hydro_47 PF01532.15 ETO30503.1 - 4.1e-63 213.6 0.1 5.5e-63 213.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4480 PF13715.1 ETO30503.1 - 0.061 13.3 0.1 0.46 10.5 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4480) DUF2681 PF10883.3 ETO30503.1 - 3.6 7.8 6.9 12 6.1 4.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Peptidase_S49 PF01343.13 ETO30504.1 - 3.5e-63 212.0 0.3 2.4e-40 137.8 1.8 3.4 2 1 0 2 2 2 2 Peptidase family S49 CLP_protease PF00574.18 ETO30504.1 - 3.5e-05 23.5 0.3 0.00093 18.9 0.1 3.0 2 0 0 2 2 2 1 Clp protease SDH_sah PF01972.11 ETO30504.1 - 0.00014 20.7 0.0 0.00068 18.5 0.0 2.0 2 0 0 2 2 2 1 Serine dehydrogenase proteinase GST_C_3 PF14497.1 ETO30506.1 - 2.7e-05 24.5 0.7 8.8e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 ETO30506.1 - 0.00021 21.4 0.0 0.00043 20.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 ETO30506.1 - 0.0021 18.0 0.3 0.0074 16.2 0.2 2.0 2 0 0 2 2 2 1 Glutaredoxin GST_C PF00043.20 ETO30506.1 - 0.0093 15.9 0.9 0.016 15.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GOLD_2 PF13897.1 ETO30506.1 - 0.031 14.5 0.4 0.05 13.8 0.3 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Daxx PF03344.10 ETO30506.1 - 0.042 12.3 2.7 0.053 12.0 1.8 1.1 1 0 0 1 1 1 0 Daxx Family MRVI1 PF05781.7 ETO30506.1 - 0.066 11.6 2.8 0.093 11.1 1.9 1.1 1 0 0 1 1 1 0 MRVI1 protein Ank PF00023.25 ETO30508.1 - 1.6e-66 216.9 11.2 6e-09 35.2 0.0 9.7 10 0 0 10 10 10 8 Ankyrin repeat Ank_2 PF12796.2 ETO30508.1 - 3.8e-66 219.4 0.7 6.7e-17 61.6 0.0 5.4 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO30508.1 - 6.6e-59 195.3 16.3 1.5e-11 44.4 0.1 8.4 4 3 5 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO30508.1 - 2.2e-50 163.6 6.3 3.2e-06 26.8 0.0 10.0 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.1 ETO30508.1 - 6.1e-45 150.2 11.3 1e-09 38.3 0.3 8.4 4 2 4 8 8 8 7 Ankyrin repeats (many copies) pRN1_helical PF13010.1 ETO30508.1 - 0.033 13.8 0.5 22 4.6 0.0 3.8 3 1 1 4 4 4 0 Primase helical domain Rep_4 PF05797.6 ETO30509.1 - 0.0037 16.0 0.3 0.0058 15.3 0.2 1.3 1 0 0 1 1 1 1 Yeast trans-acting factor (REP1/REP2) BACK PF07707.10 ETO30509.1 - 0.26 11.1 5.2 3.6 7.4 0.4 2.6 2 0 0 2 2 2 0 BTB And C-terminal Kelch DUF1732 PF08340.6 ETO30512.1 - 0.051 13.4 1.5 2.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1732) NEMO PF11577.3 ETO30513.1 - 0.082 12.6 0.1 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO MARVEL PF01284.18 ETO30514.1 - 0.0016 18.2 1.8 1.2 8.9 0.0 3.4 4 0 0 4 4 4 2 Membrane-associating domain Tetraspannin PF00335.15 ETO30514.1 - 0.29 10.3 13.5 14 4.8 0.0 3.3 2 1 0 2 2 2 0 Tetraspanin family GCD14 PF08704.5 ETO30514.1 - 0.93 8.9 9.8 0.49 9.8 1.1 2.2 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Synaptobrevin PF00957.16 ETO30514.1 - 2.7 7.6 8.9 0.88 9.2 0.9 3.3 3 0 0 3 3 3 0 Synaptobrevin Peptidase_S49_N PF08496.5 ETO30514.1 - 2.8 7.7 15.7 1.6 8.5 0.5 2.8 3 0 0 3 3 3 0 Peptidase family S49 N-terminal DUF874 PF05917.6 ETO30515.1 - 0.15 10.9 7.3 0.18 10.6 5.1 1.0 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) Herpes_DNAp_acc PF04929.7 ETO30515.1 - 0.52 9.2 4.8 0.56 9.1 3.4 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DEAD PF00270.24 ETO30516.1 - 7.2e-29 100.4 0.1 2e-28 98.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETO30516.1 - 2.2e-12 46.6 0.0 8.2e-12 44.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.1 ETO30516.1 - 7.7e-06 25.1 0.2 2.5e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit NIF PF03031.13 ETO30516.1 - 0.0099 15.5 0.5 0.015 14.9 0.4 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ResIII PF04851.10 ETO30516.1 - 0.012 15.4 0.2 0.061 13.1 0.0 2.2 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit RRM_1 PF00076.17 ETO30517.1 - 4.5e-05 23.0 0.4 0.0001 21.8 0.3 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO30517.1 - 7.7e-05 22.5 0.1 0.00016 21.5 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Innate_immun PF12782.2 ETO30517.1 - 0.72 9.0 12.4 1.4 8.0 7.5 2.1 1 1 0 1 1 1 0 Invertebrate innate immunity transcript family HTH_Tnp_ISL3 PF13542.1 ETO30519.1 - 0.099 11.8 0.1 0.24 10.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DUF1977 PF09320.6 ETO30520.1 - 0.1 12.8 3.5 4.5 7.5 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1977) RabGAP-TBC PF00566.13 ETO30522.1 - 0.1 12.0 0.0 0.1 12.0 0.0 3.5 1 1 0 3 3 3 0 Rab-GTPase-TBC domain SOBP PF15279.1 ETO30522.1 - 5.7 7.2 13.8 9.2 6.5 9.6 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DUF1675 PF07897.6 ETO30523.1 - 0.062 13.1 8.5 0.11 12.3 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Mcp5_PH PF12814.2 ETO30523.1 - 0.12 12.3 3.7 0.21 11.4 1.2 2.3 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology PDR_CDR PF06422.7 ETO30524.1 - 0.016 14.8 0.9 0.048 13.3 0.6 1.8 1 0 0 1 1 1 0 CDR ABC transporter Meiosis_expr PF15163.1 ETO30524.1 - 0.041 14.2 0.0 0.085 13.2 0.0 1.5 1 0 0 1 1 1 0 Meiosis-expressed DUF4636 PF15468.1 ETO30524.1 - 0.081 12.3 0.2 0.081 12.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4636) Grp1_Fun34_YaaH PF01184.14 ETO30524.1 - 0.67 9.2 0.0 0.67 9.2 0.0 2.4 2 1 1 3 3 3 0 GPR1/FUN34/yaaH family SdpI PF13630.1 ETO30524.1 - 3.6 7.3 10.5 1.5 8.5 0.1 2.5 2 0 0 2 2 2 0 SdpI/YhfL protein family CH PF00307.26 ETO30525.1 - 1.4e-07 31.4 0.4 3.7e-07 30.1 0.1 1.7 1 1 1 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 ETO30525.1 - 0.11 12.1 0.2 0.31 10.7 0.1 1.8 1 1 1 2 2 2 0 CAMSAP CH domain zf-RING_2 PF13639.1 ETO30526.1 - 1.1e-14 53.9 6.3 1.1e-14 53.9 4.4 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 ETO30526.1 - 3.1e-09 36.3 4.2 3.1e-09 36.3 2.9 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 ETO30526.1 - 2.4e-08 33.9 3.5 2.4e-08 33.9 2.5 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 ETO30526.1 - 8e-08 31.8 4.5 8e-08 31.8 3.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO30526.1 - 1.6e-07 30.8 6.7 1.6e-07 30.8 4.6 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO30526.1 - 2.1e-06 27.6 6.8 2.1e-06 27.6 4.7 3.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 ETO30526.1 - 0.00049 19.8 2.1 0.00049 19.8 1.5 2.8 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 ETO30526.1 - 0.0069 16.0 4.7 0.0069 16.0 3.2 2.4 3 0 0 3 3 3 1 RING-type zinc-finger Baculo_RING PF05883.6 ETO30526.1 - 0.028 14.2 0.8 0.067 13.0 0.5 1.7 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain RINGv PF12906.2 ETO30526.1 - 0.45 10.5 8.8 0.088 12.8 2.8 2.5 2 0 0 2 2 1 0 RING-variant domain Rtf2 PF04641.7 ETO30526.1 - 0.48 9.5 5.4 0.071 12.2 0.2 2.0 2 0 0 2 2 2 0 Rtf2 RING-finger Prok-RING_1 PF14446.1 ETO30526.1 - 0.96 9.2 5.1 7 6.4 3.6 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.1 ETO30526.1 - 1.7 8.2 9.3 0.91 9.1 3.6 2.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain AF-4 PF05110.8 ETO30526.1 - 9.1 3.9 11.6 15 3.2 8.1 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PH PF00169.24 ETO30527.1 - 9.2e-05 22.5 1.0 0.0002 21.5 0.7 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 ETO30527.1 - 0.00033 20.8 0.3 0.00095 19.3 0.2 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain CobT PF06213.7 ETO30527.1 - 0.0012 18.0 12.2 0.0012 18.0 8.5 1.4 2 0 0 2 2 2 1 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 ETO30527.1 - 0.038 11.9 14.7 0.056 11.3 10.2 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 ETO30527.1 - 0.048 12.9 13.1 0.079 12.2 9.1 1.4 1 0 0 1 1 1 0 SDA1 DUF3348 PF11828.3 ETO30527.1 - 0.087 12.2 0.1 0.26 10.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) CDC45 PF02724.9 ETO30527.1 - 0.094 10.7 12.1 0.17 9.8 8.4 1.4 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 ETO30527.1 - 0.23 9.9 16.0 0.34 9.3 11.1 1.2 1 0 0 1 1 1 0 Daxx Family Zip PF02535.17 ETO30527.1 - 1.1 8.2 3.5 1.3 7.9 2.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TRAP_alpha PF03896.11 ETO30527.1 - 1.8 7.5 9.2 3.4 6.5 6.4 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CPSF100_C PF13299.1 ETO30527.1 - 2.8 8.0 8.9 0.39 10.8 3.1 1.8 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Sporozoite_P67 PF05642.6 ETO30527.1 - 3.4 5.4 9.5 4.7 4.9 6.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Trypan_PARP PF05887.6 ETO30527.1 - 8.2 6.2 8.1 14 5.4 5.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ank_2 PF12796.2 ETO30528.1 - 1.2e-71 237.0 12.3 2.3e-18 66.2 0.5 6.0 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO30528.1 - 1.7e-41 139.8 7.3 1e-08 35.4 0.0 9.6 6 1 4 10 10 10 9 Ankyrin repeats (many copies) Ank PF00023.25 ETO30528.1 - 6.2e-39 129.9 6.0 1.3e-05 24.7 0.0 10.3 11 0 0 11 11 11 6 Ankyrin repeat Ank_3 PF13606.1 ETO30528.1 - 7.8e-34 112.3 4.8 0.0028 17.7 0.1 10.5 11 0 0 11 11 11 7 Ankyrin repeat Ank_5 PF13857.1 ETO30528.1 - 1.8e-33 113.8 14.8 2.9e-06 27.3 0.1 8.9 4 3 4 9 9 9 7 Ankyrin repeats (many copies) XK-related PF09815.4 ETO30529.1 - 0.00071 18.6 16.9 0.0057 15.6 11.8 2.3 1 1 0 1 1 1 1 XK-related protein UQ_con PF00179.21 ETO30530.1 - 1.1e-40 138.3 1.1 4.5e-40 136.3 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme F-box-like PF12937.2 ETO30530.1 - 1.9e-06 27.5 0.5 5.5e-06 26.0 0.3 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 ETO30530.1 - 2.6e-06 26.9 0.3 6.1e-06 25.7 0.2 1.5 1 0 0 1 1 1 1 F-box domain RWD PF05773.17 ETO30530.1 - 0.037 13.9 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 RWD domain TPR_12 PF13424.1 ETO30532.1 - 7.3e-68 224.4 12.0 1.2e-18 66.8 0.0 4.2 1 1 3 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.23 ETO30532.1 - 4.6e-36 120.9 23.2 4.6e-07 29.1 0.0 6.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 ETO30532.1 - 2e-29 99.1 30.2 4e-05 23.0 0.1 7.4 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETO30532.1 - 1.4e-28 98.3 12.7 2.8e-12 46.0 0.9 4.3 3 1 1 4 4 4 4 TPR repeat TPR_2 PF07719.12 ETO30532.1 - 6.3e-27 91.2 10.3 0.00029 20.5 0.0 7.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.1 ETO30532.1 - 1.7e-25 86.7 1.8 0.00017 21.1 0.0 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETO30532.1 - 4.7e-23 80.3 0.0 0.0015 18.3 0.0 5.6 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_17 PF13431.1 ETO30532.1 - 4.9e-19 66.8 6.5 0.0021 18.1 0.1 6.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 ETO30532.1 - 2.5e-12 47.1 0.0 0.0027 18.3 0.0 4.4 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_6 PF13174.1 ETO30532.1 - 5.2e-09 35.9 5.2 1 9.9 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO30532.1 - 3.2e-07 30.3 0.0 1.5 9.6 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO30532.1 - 5.5e-07 28.7 9.7 0.13 11.5 0.0 5.7 6 0 0 6 6 6 3 SHNi-TPR TPR_19 PF14559.1 ETO30532.1 - 3.3e-05 24.1 1.9 0.47 10.8 0.0 3.5 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_3 PF07720.7 ETO30532.1 - 9.9e-05 22.0 12.6 0.96 9.3 0.1 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 ETO30532.1 - 0.00025 21.1 14.6 0.0096 16.0 1.7 3.7 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 ETO30532.1 - 0.0011 18.8 8.2 1.5 8.7 0.1 4.7 4 1 1 5 5 5 2 MIT (microtubule interacting and transport) domain mit_SMPDase PF14724.1 ETO30532.1 - 0.05 11.4 3.8 0.6 7.8 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial-associated sphingomyelin phosphodiesterase OATP PF03137.15 ETO30533.1 - 0.14 10.1 0.8 0.17 9.8 0.5 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SPATIAL PF15256.1 ETO30533.1 - 1.7 8.6 7.9 2.1 8.3 5.5 1.2 1 0 0 1 1 1 0 SPATIAL BCIP PF13862.1 ETO30533.1 - 3.6 7.0 8.4 0.12 11.8 0.8 1.8 1 1 1 2 2 2 0 p21-C-terminal region-binding protein ETRAMP PF09716.5 ETO30533.1 - 4.4 7.3 10.1 6 6.8 0.0 2.2 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) RecX PF02631.11 ETO30534.1 - 0.092 12.9 1.6 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 RecX family Use1 PF09753.4 ETO30535.1 - 3e-07 30.1 5.6 3e-07 30.1 3.9 2.8 2 2 0 2 2 2 1 Membrane fusion protein Use1 Peptidase_M9_N PF08453.5 ETO30535.1 - 0.1 11.9 0.1 0.1 11.9 0.1 2.6 2 1 1 3 3 3 0 Peptidase family M9 N-terminal DUF3753 PF12575.3 ETO30535.1 - 0.38 10.5 2.9 1.6 8.5 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) DUF972 PF06156.8 ETO30535.1 - 4.1 7.7 16.9 1.4 9.2 2.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF972) SOBP PF15279.1 ETO30535.1 - 8.7 6.6 10.4 13 6.0 7.2 1.3 1 1 0 1 1 1 0 Sine oculis-binding protein WD40 PF00400.27 ETO30536.1 - 0.15 11.9 0.1 0.57 10.1 0.0 2.0 2 0 0 2 2 2 0 WD domain, G-beta repeat Mucin PF01456.12 ETO30538.1 - 0.0015 18.3 7.3 0.0015 18.3 5.1 2.6 2 1 0 2 2 2 1 Mucin-like glycoprotein SurA_N_3 PF13624.1 ETO30541.1 - 0.043 13.8 4.0 0.059 13.3 0.4 2.4 2 1 0 2 2 2 0 SurA N-terminal domain Aldedh PF00171.17 ETO30543.1 - 1.7e-30 105.8 0.1 2.2e-30 105.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.17 ETO30544.1 - 1.5e-38 132.3 0.0 1.6e-38 132.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PBP1_TM PF14812.1 ETO30545.1 - 5.8 7.2 7.6 0.47 10.7 0.2 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Phasin PF05597.6 ETO30546.1 - 5.6e-05 22.9 15.9 5.6e-05 22.9 11.0 3.4 4 2 1 5 5 5 1 Poly(hydroxyalcanoate) granule associated protein (phasin) Hist_deacetyl PF00850.14 ETO30548.1 - 3.6e-49 167.7 0.5 9e-49 166.4 0.0 1.7 2 0 0 2 2 2 1 Histone deacetylase domain CENP-B_dimeris PF09026.5 ETO30549.1 - 0.00098 19.3 12.1 0.0022 18.1 8.4 1.6 1 0 0 1 1 1 1 Centromere protein B dimerisation domain CDC45 PF02724.9 ETO30549.1 - 0.0075 14.3 6.1 0.011 13.8 4.2 1.1 1 0 0 1 1 1 1 CDC45-like protein AOX PF01786.12 ETO30549.1 - 0.0077 15.6 0.3 0.016 14.6 0.2 1.4 1 0 0 1 1 1 1 Alternative oxidase TFIIA PF03153.8 ETO30549.1 - 0.031 14.1 7.8 0.045 13.6 5.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 ETO30549.1 - 0.13 10.1 14.0 0.2 9.5 9.7 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 ETO30549.1 - 0.17 11.5 9.6 0.28 10.8 6.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein YL1 PF05764.8 ETO30549.1 - 0.2 11.2 13.2 0.31 10.5 9.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein RXT2_N PF08595.6 ETO30549.1 - 0.4 10.4 10.2 0.83 9.4 7.1 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal SDA1 PF05285.7 ETO30549.1 - 1.2 8.3 12.1 1.8 7.7 8.4 1.2 1 0 0 1 1 1 0 SDA1 CobT PF06213.7 ETO30549.1 - 1.2 8.1 15.1 2 7.4 10.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sporozoite_P67 PF05642.6 ETO30549.1 - 1.6 6.5 5.4 2.2 6.0 3.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4611 PF15387.1 ETO30549.1 - 3.8 7.7 12.5 6.1 7.0 7.9 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF4611) Daxx PF03344.10 ETO30549.1 - 3.8 5.8 13.8 6 5.2 9.6 1.2 1 0 0 1 1 1 0 Daxx Family Sigma70_ner PF04546.8 ETO30549.1 - 9.4 5.7 14.9 19 4.8 10.3 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region RR_TM4-6 PF06459.7 ETO30550.1 - 0.0061 16.4 1.0 0.0071 16.2 0.7 1.0 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 SelP_N PF04592.9 ETO30550.1 - 0.023 14.0 4.3 0.03 13.7 3.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Peptidase_S49_N PF08496.5 ETO30550.1 - 0.031 14.0 9.9 0.038 13.7 6.9 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Serinc PF03348.10 ETO30550.1 - 0.039 12.6 2.4 0.041 12.6 1.6 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) RP-C_C PF11800.3 ETO30550.1 - 0.062 12.9 2.6 0.069 12.8 1.8 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF3121 PF11319.3 ETO30550.1 - 0.065 12.7 2.6 0.088 12.3 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3121) DUF3139 PF11337.3 ETO30550.1 - 0.066 13.4 1.8 0.095 12.9 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) Nucleoside_tran PF01733.13 ETO30550.1 - 0.15 11.1 1.3 0.18 10.9 0.9 1.0 1 0 0 1 1 1 0 Nucleoside transporter DUF2291 PF10054.4 ETO30550.1 - 0.26 10.5 2.1 0.56 9.4 0.8 1.7 1 1 1 2 2 2 0 Predicted periplasmic lipoprotein (DUF2291) DUF4435 PF14491.1 ETO30550.1 - 0.28 10.9 7.2 0.33 10.7 5.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4435) HCO3_cotransp PF00955.16 ETO30550.1 - 0.35 9.4 2.6 0.38 9.3 1.8 1.1 1 0 0 1 1 1 0 HCO3- transporter family Peroxin-13_N PF04088.8 ETO30550.1 - 0.45 10.4 3.4 0.56 10.1 2.4 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Peptidase_U57 PF05582.7 ETO30550.1 - 0.65 8.9 4.7 0.75 8.7 3.3 1.1 1 0 0 1 1 1 0 YabG peptidase U57 YqfQ PF14181.1 ETO30550.1 - 1.8 8.5 12.0 2.4 8.1 8.3 1.1 1 0 0 1 1 1 0 YqfQ-like protein DUF1168 PF06658.7 ETO30550.1 - 3.7 7.0 17.8 6 6.3 12.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Sec62 PF03839.11 ETO30550.1 - 4 6.7 10.3 4.7 6.5 7.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 NARP1 PF12569.3 ETO30550.1 - 4 6.0 11.9 4.9 5.7 8.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Pkinase PF00069.20 ETO30551.1 - 4.8e-05 22.6 0.0 6.1e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Basic PF01586.11 ETO30551.1 - 0.096 13.4 0.1 0.13 13.0 0.1 1.3 1 0 0 1 1 1 0 Myogenic Basic domain Pkinase PF00069.20 ETO30552.1 - 4.3e-59 199.7 0.7 9.1e-59 198.7 0.5 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO30552.1 - 1.3e-41 142.4 0.2 2.7e-41 141.3 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO30552.1 - 1.1e-07 31.0 0.0 2.8e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 ETO30552.1 - 4.8e-05 23.2 0.1 0.00014 21.6 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 ETO30552.1 - 9.2e-05 21.5 0.2 0.0002 20.5 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 ETO30552.1 - 0.00039 20.0 0.2 0.00039 20.0 0.1 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 ETO30552.1 - 0.0048 16.2 0.0 0.012 14.9 0.0 1.6 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL SR-25 PF10500.4 ETO30552.1 - 0.008 15.6 15.6 0.012 15.1 10.8 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Seadorna_VP7 PF07387.6 ETO30552.1 - 0.072 11.9 0.5 0.31 9.8 0.0 1.9 2 0 0 2 2 2 0 Seadornavirus VP7 DDHD PF02862.12 ETO30552.1 - 0.33 10.7 9.4 0.047 13.4 3.7 1.6 2 0 0 2 2 2 0 DDHD domain PLRV_ORF5 PF01690.12 ETO30552.1 - 2.6 7.1 14.5 3.5 6.6 10.1 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein NPR3 PF03666.8 ETO30552.1 - 5.5 5.4 11.0 13 4.1 7.6 1.6 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Tir_receptor_C PF07489.6 ETO30552.1 - 7.9 6.1 9.2 0.12 12.1 0.4 2.0 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus GPCR_chapero_1 PF11904.3 ETO30553.1 - 3.2e-32 111.9 23.7 1.7e-28 99.6 16.5 2.6 1 1 0 1 1 1 1 GPCR-chaperone YCII PF03795.9 ETO30553.1 - 0.06 13.5 0.1 0.14 12.4 0.1 1.6 1 0 0 1 1 1 0 YCII-related domain YTH PF04146.10 ETO30554.1 - 2.9e-07 30.1 0.0 2.9e-07 30.1 0.0 2.7 2 1 1 3 3 3 1 YT521-B-like domain Utp14 PF04615.8 ETO30554.1 - 1.2 7.1 46.1 1.6 6.7 31.9 1.3 1 0 0 1 1 1 0 Utp14 protein DSPc PF00782.15 ETO30556.1 - 1.5e-23 82.8 0.0 2.2e-23 82.2 0.0 1.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 ETO30556.1 - 0.00064 18.7 0.1 0.00072 18.5 0.1 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase3 PF13350.1 ETO30556.1 - 0.004 17.4 0.0 0.0098 16.1 0.0 1.8 2 1 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 ETO30556.1 - 0.012 14.9 0.1 0.014 14.7 0.0 1.4 1 1 0 1 1 1 0 Protein-tyrosine phosphatase CRAL_TRIO_2 PF13716.1 ETO30556.1 - 0.039 13.8 0.7 0.055 13.3 0.5 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain PTPlike_phytase PF14566.1 ETO30556.1 - 0.12 12.3 0.0 0.28 11.2 0.0 1.6 1 1 0 1 1 1 0 Inositol hexakisphosphate Trichoplein PF13868.1 ETO30558.1 - 0.0052 15.2 24.7 0.0052 15.2 17.1 3.1 3 0 0 3 3 3 2 Tumour suppressor, Mitostatin Cyto_heme_lyase PF01265.12 ETO30559.1 - 3.2e-20 72.8 0.8 4.2e-20 72.4 0.6 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase ADK PF00406.17 ETO30560.1 - 4.1e-52 176.0 0.2 7.3e-52 175.2 0.2 1.4 1 1 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 ETO30560.1 - 1.8e-15 56.2 0.1 4.9e-15 54.9 0.1 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid Tox-ART-HYE1 PF15634.1 ETO30560.1 - 0.097 11.6 0.0 0.2 10.6 0.0 1.4 1 1 0 1 1 1 0 HYE1 signature containing ADP-ribosyltransferase BUD22 PF09073.5 ETO30561.1 - 0.0023 17.0 1.3 0.0028 16.7 0.9 1.0 1 0 0 1 1 1 1 BUD22 DUF3757 PF12582.3 ETO30561.1 - 0.09 12.9 0.5 0.14 12.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3757) DUF2315 PF10231.4 ETO30562.1 - 0.022 14.6 0.6 0.029 14.2 0.4 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2315) Med15_fungi PF05397.7 ETO30562.1 - 0.045 13.7 0.1 0.062 13.2 0.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 15 WSC PF01822.14 ETO30562.1 - 0.12 12.3 0.2 0.2 11.6 0.1 1.3 1 1 0 1 1 1 0 WSC domain Ndc1_Nup PF09531.5 ETO30563.1 - 0.053 11.9 0.5 0.059 11.7 0.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FRQ PF09421.5 ETO30563.1 - 0.49 8.0 4.4 0.58 7.8 3.1 1.0 1 0 0 1 1 1 0 Frequency clock protein Herpes_DNAp_acc PF04929.7 ETO30563.1 - 3 6.7 7.3 4 6.3 5.1 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor zf-C2HC_2 PF13913.1 ETO30565.1 - 2.5e-15 55.6 7.7 1.5e-09 37.2 0.8 2.6 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2 PF00096.21 ETO30565.1 - 8.7e-06 25.7 2.0 0.0071 16.6 0.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 ETO30565.1 - 0.00019 21.4 2.4 0.011 15.8 0.2 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 ETO30565.1 - 0.004 17.3 7.7 0.076 13.3 0.2 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-ribbon_3 PF13248.1 ETO30565.1 - 0.0045 16.1 1.2 0.62 9.3 0.1 2.5 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 ETO30565.1 - 0.017 14.5 3.0 0.67 9.5 0.1 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-CHCC PF10276.4 ETO30565.1 - 0.11 12.3 4.7 0.2 11.5 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger domain Sgf11 PF08209.6 ETO30565.1 - 0.2 10.9 6.8 0.47 9.8 0.2 2.5 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Nairovirus_M PF07948.6 ETO30565.1 - 0.59 8.1 12.8 0.22 9.5 0.5 3.2 4 0 0 4 4 4 0 Nairovirus M polyprotein-like HypA PF01155.14 ETO30565.1 - 0.6 9.8 4.5 8 6.1 0.2 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Prok-RING_1 PF14446.1 ETO30565.1 - 1.2 8.9 5.4 8.5 6.1 0.1 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-H2C2_2 PF13465.1 ETO30565.1 - 5.3 7.5 8.3 4.4 7.7 0.1 2.9 3 0 0 3 3 2 0 Zinc-finger double domain DEP PF00610.16 ETO30566.1 - 0.0016 18.1 0.0 0.0051 16.5 0.0 1.9 1 1 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Nucleoplasmin PF03066.10 ETO30566.1 - 0.0072 15.8 7.3 0.0072 15.8 5.1 2.3 2 0 0 2 2 2 1 Nucleoplasmin BSP_II PF05432.6 ETO30566.1 - 0.15 11.2 17.0 0.48 9.6 11.8 1.8 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Ribosomal_60s PF00428.14 ETO30566.1 - 1.9 8.9 14.6 0.48 10.8 7.0 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Herpes_capsid PF06112.6 ETO30566.1 - 2.8 7.9 18.1 0.99 9.4 6.9 2.9 2 1 0 2 2 2 0 Gammaherpesvirus capsid protein CENP-B_dimeris PF09026.5 ETO30566.1 - 4.7 7.5 15.4 12 6.1 10.0 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Sporozoite_P67 PF05642.6 ETO30566.1 - 8.2 4.1 21.8 0.34 8.7 1.1 2.3 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Nop14 PF04147.7 ETO30568.1 - 0.0083 14.1 8.2 0.011 13.7 5.7 1.1 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 ETO30568.1 - 3.4 6.0 11.6 4.4 5.6 8.0 1.2 1 0 0 1 1 1 0 Daxx Family Mannosyl_trans3 PF11051.3 ETO30569.1 - 1.2e-14 54.3 0.1 1.6e-14 53.9 0.1 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative WEMBL PF05701.6 ETO30570.1 - 0.00026 19.5 17.6 0.00043 18.8 12.2 1.3 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Cyclophil_like PF04126.8 ETO30570.1 - 0.041 13.4 0.0 0.097 12.2 0.0 1.7 1 0 0 1 1 1 0 Cyclophilin-like TPR_MLP1_2 PF07926.7 ETO30570.1 - 4.6 6.9 42.6 1.4 8.6 16.8 2.9 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF2716 PF10898.3 ETO30571.1 - 0.88 9.5 3.5 0.44 10.5 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2716) SDH_alpha PF03313.10 ETO30571.1 - 1.3 8.0 4.4 1.7 7.6 3.0 1.3 1 0 0 1 1 1 0 Serine dehydratase alpha chain PBP1_TM PF14812.1 ETO30573.1 - 0.29 11.4 3.1 0.45 10.8 2.1 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HEAT PF02985.17 ETO30577.1 - 4.8e-08 32.4 0.4 0.042 13.9 0.1 4.9 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 ETO30577.1 - 0.0071 16.6 0.2 4.1 7.7 0.0 3.1 2 1 1 3 3 3 3 HEAT repeats Vac14_Fab1_bd PF12755.2 ETO30577.1 - 0.057 13.8 1.4 1.8 9.0 0.0 3.5 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region PT PF04886.7 ETO30578.1 - 3.8e-08 32.5 156.4 1.5e+04 -11.8 45.3 8.0 1 1 1 2 2 2 0 PT repeat EF-hand_7 PF13499.1 ETO30580.1 - 1.9e-25 88.7 11.5 1.2e-14 54.2 1.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 ETO30580.1 - 3.4e-25 85.3 18.8 9e-09 34.0 0.7 5.0 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 ETO30580.1 - 3.3e-23 81.0 18.0 7.1e-12 44.7 0.7 5.0 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_6 PF13405.1 ETO30580.1 - 3e-22 76.4 8.7 2.4e-07 30.0 0.1 4.3 3 1 1 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 ETO30580.1 - 3.3e-16 57.8 7.7 4.6e-05 22.5 0.1 4.0 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 ETO30580.1 - 8.9e-13 47.9 0.4 3.3e-06 26.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 ETO30580.1 - 0.00022 20.9 7.7 0.0027 17.4 0.9 2.9 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand Cytochrome_CBB3 PF13442.1 ETO30580.1 - 0.00057 19.9 0.2 0.02 15.0 0.0 2.3 2 0 0 2 2 2 1 Cytochrome C oxidase, cbb3-type, subunit III SPARC_Ca_bdg PF10591.4 ETO30580.1 - 0.00059 19.8 2.7 0.055 13.5 0.1 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Toprim PF01751.17 ETO30580.1 - 0.0025 17.7 0.2 3.2 7.7 0.0 2.6 1 1 2 3 3 3 2 Toprim domain GTPase_Cys_C PF12631.2 ETO30580.1 - 0.0031 17.8 1.1 1.6 9.2 0.0 2.3 2 0 0 2 2 2 2 Catalytic cysteine-containing C-terminus of GTPase, MnmE TerB PF05099.8 ETO30580.1 - 0.0062 16.2 1.2 0.022 14.4 0.2 2.0 1 1 1 2 2 2 1 Tellurite resistance protein TerB DUF1456 PF07308.8 ETO30580.1 - 0.0068 16.4 2.3 0.54 10.3 0.1 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1456) Toprim_2 PF13155.1 ETO30580.1 - 0.012 15.9 4.3 0.28 11.5 0.3 2.7 1 1 1 2 2 2 0 Toprim-like UPF0154 PF03672.8 ETO30580.1 - 0.03 13.9 0.0 2.9 7.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Toprim_4 PF13662.1 ETO30580.1 - 0.054 13.5 0.4 3.4 7.7 0.0 2.8 2 1 1 3 3 3 0 Toprim domain LNS2 PF08235.8 ETO30580.1 - 0.073 12.6 0.1 0.21 11.1 0.0 1.7 1 1 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) MscS_porin PF12795.2 ETO30580.1 - 0.091 12.0 0.5 4.9 6.4 0.0 2.0 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF592 PF04574.8 ETO30580.1 - 0.099 12.1 0.6 0.24 10.9 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF592) MgtE_N PF03448.12 ETO30580.1 - 0.11 12.7 5.3 0.092 13.0 1.2 2.1 1 1 1 2 2 2 0 MgtE intracellular N domain YtzH PF14165.1 ETO30580.1 - 0.21 11.8 1.7 0.34 11.1 0.3 1.9 1 1 1 2 2 2 0 YtzH-like protein DUF4252 PF14060.1 ETO30580.1 - 0.28 10.7 5.2 0.54 9.8 2.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4252) p25-alpha PF05517.7 ETO30580.1 - 0.4 10.9 5.7 0.18 12.0 0.9 2.1 1 1 1 2 2 2 0 p25-alpha DUF1104 PF06518.6 ETO30580.1 - 0.4 10.8 5.8 0.13 12.4 2.0 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF1104) DUF1007 PF06226.8 ETO30580.1 - 1.1 8.8 4.2 25 4.5 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1007) DUF3887 PF13026.1 ETO30580.1 - 1.2 9.4 10.4 0.44 10.8 1.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3887) KOW PF00467.24 ETO30584.1 - 0.00032 20.3 1.0 0.00032 20.3 0.7 1.9 2 0 0 2 2 2 1 KOW motif Pinin_SDK_memA PF04696.8 ETO30584.1 - 0.97 9.0 8.9 1.4 8.5 2.1 2.5 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region WD40 PF00400.27 ETO30585.1 - 3.2e-160 515.0 49.8 1.1e-10 41.0 0.0 15.5 15 0 0 15 15 15 15 WD domain, G-beta repeat Nup160 PF11715.3 ETO30585.1 - 7.1e-11 40.9 27.2 0.066 11.3 0.4 10.9 1 1 7 10 10 10 6 Nucleoporin Nup120/160 DUF1258 PF06869.7 ETO30585.1 - 1.4e-08 34.1 1.1 1.1 8.2 0.0 6.1 3 1 2 6 6 6 3 Protein of unknown function (DUF1258) NACHT PF05729.7 ETO30585.1 - 2.1e-08 33.9 0.0 4.6e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Pentapeptide PF00805.17 ETO30585.1 - 1.8e-05 23.8 1.4 3.5e-05 22.9 0.9 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO30585.1 - 3.1e-05 23.7 0.5 9.4e-05 22.1 0.4 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) PQQ_2 PF13360.1 ETO30585.1 - 9.4e-05 21.9 3.1 0.27 10.6 0.1 4.2 1 1 3 4 4 4 3 PQQ-like domain Pentapeptide_3 PF13576.1 ETO30585.1 - 0.0008 19.2 0.5 0.0023 17.7 0.4 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA_18 PF13238.1 ETO30585.1 - 0.0013 19.0 0.5 0.011 16.0 0.0 2.7 1 1 1 2 2 2 1 AAA domain Cytochrom_D1 PF02239.11 ETO30585.1 - 0.0047 15.2 10.5 0.4 8.9 0.1 5.1 4 1 2 7 7 7 1 Cytochrome D1 heme domain AAA_22 PF13401.1 ETO30585.1 - 0.0072 16.4 0.0 0.023 14.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO30585.1 - 0.016 16.0 0.1 0.11 13.2 0.0 2.6 2 0 0 2 2 1 0 AAA domain PD40 PF07676.7 ETO30585.1 - 3.9 7.2 18.5 22 4.8 0.1 7.5 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat Pkinase PF00069.20 ETO30586.1 - 1.5e-24 86.5 0.0 1.8e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO30586.1 - 1.5e-07 30.7 0.0 2e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 ETO30586.1 - 1.6e-05 25.3 1.1 2.7e-05 24.5 0.8 1.3 1 0 0 1 1 1 1 Protein kinase C terminal domain VWA_3 PF13768.1 ETO30587.1 - 1.5e-07 31.2 0.4 0.004 16.8 0.2 2.6 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA PF00092.23 ETO30587.1 - 2.7e-06 27.2 0.2 0.00084 19.1 0.0 2.6 2 1 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.1 ETO30587.1 - 6.6e-06 26.3 6.6 1.6e-05 25.0 1.9 2.7 2 1 0 2 2 2 1 von Willebrand factor type A domain DUF4398 PF14346.1 ETO30587.1 - 0.051 13.6 2.9 0.052 13.5 0.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) Glyco_transf_92 PF01697.22 ETO30588.1 - 7.3e-20 71.4 2.6 4.9e-19 68.7 1.8 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.1 ETO30588.1 - 5.1e-08 33.1 0.0 1.9e-07 31.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 2 DDHD PF02862.12 ETO30589.1 - 0.018 14.8 3.1 0.029 14.1 2.2 1.3 1 0 0 1 1 1 0 DDHD domain Nucleoplasmin PF03066.10 ETO30589.1 - 0.039 13.4 4.1 2.2 7.7 0.1 2.2 2 0 0 2 2 2 0 Nucleoplasmin Mo-nitro_C PF06967.6 ETO30589.1 - 0.13 12.4 0.0 0.61 10.2 0.0 2.0 2 0 0 2 2 2 0 Mo-dependent nitrogenase C-terminus Zip PF02535.17 ETO30589.1 - 0.14 11.1 0.1 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CAF-1_p150 PF11600.3 ETO30589.1 - 1.6 8.0 16.8 2.5 7.4 11.6 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal WD40 PF00400.27 ETO30590.1 - 1e-58 193.2 26.1 2.9e-13 49.1 0.3 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO30590.1 - 1.3e-10 40.0 6.8 0.071 11.2 0.0 5.2 1 1 3 5 5 5 5 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO30590.1 - 0.0024 17.6 2.0 0.37 10.5 0.2 4.1 2 1 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 ETO30590.1 - 0.0041 15.9 4.6 0.76 8.4 0.2 4.4 1 1 2 4 4 4 1 Nup133 N terminal like XH PF03469.9 ETO30590.1 - 0.059 13.0 0.8 0.12 12.0 0.6 1.5 1 0 0 1 1 1 0 XH domain DUF2415 PF10313.4 ETO30590.1 - 0.16 11.7 1.9 8.2 6.1 0.1 3.1 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) DUF3380 PF11860.3 ETO30591.1 - 0.045 13.7 0.1 0.058 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3380) Cation_ATPase_N PF00690.21 ETO30591.1 - 0.11 11.9 0.4 0.46 9.9 0.1 2.0 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus BUD22 PF09073.5 ETO30594.1 - 0.14 11.1 33.3 0.17 10.9 23.1 1.1 1 0 0 1 1 1 0 BUD22 Atg14 PF10186.4 ETO30594.1 - 1.1 8.1 12.2 1.3 7.9 8.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF159 PF02586.9 ETO30594.1 - 1.3 8.4 8.4 0.43 10.0 3.5 1.7 1 1 1 2 2 2 0 Uncharacterised ACR, COG2135 MIP-T3 PF10243.4 ETO30594.1 - 2.7 6.3 34.0 3.2 6.1 23.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CENP-B_dimeris PF09026.5 ETO30594.1 - 3.3 8.0 23.5 0.21 11.8 1.9 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain MSV199 PF10553.4 ETO30595.1 - 0.074 12.9 0.6 0.12 12.3 0.4 1.4 1 0 0 1 1 1 0 MSV199 domain BioW PF03744.8 ETO30595.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 6-carboxyhexanoate--CoA ligase ATG27 PF09451.5 ETO30595.1 - 0.72 9.0 2.6 1.2 8.2 1.8 1.4 1 0 0 1 1 1 0 Autophagy-related protein 27 CTDII PF01556.13 ETO30596.1 - 1.5e-24 85.7 1.6 3.7e-18 65.1 0.0 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 ETO30596.1 - 6.6e-11 42.0 11.5 1.9e-10 40.6 8.0 1.9 1 0 0 1 1 1 1 DnaJ central domain Vps39_2 PF10367.4 ETO30596.1 - 0.032 14.4 3.6 0.28 11.3 0.1 2.7 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 SCFA_trans PF02667.9 ETO30596.1 - 0.14 10.9 1.1 0.24 10.1 0.8 1.3 1 0 0 1 1 1 0 Short chain fatty acid transporter A2L_zn_ribbon PF08792.5 ETO30596.1 - 2.3 7.7 17.4 6 6.4 0.1 4.6 3 1 1 4 4 4 0 A2L zinc ribbon domain HypA PF01155.14 ETO30596.1 - 3.9 7.1 10.9 5 6.8 1.5 2.7 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family PS_Dcarbxylase PF02666.10 ETO30597.1 - 9.4e-49 165.4 0.0 5.5e-48 162.9 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylserine decarboxylase C2 PF00168.25 ETO30597.1 - 3.7e-30 103.5 0.0 2.7e-20 71.9 0.0 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_6 PF13405.1 ETO30597.1 - 3e-07 29.7 0.8 0.013 15.3 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 ETO30597.1 - 0.00046 19.2 1.1 0.004 16.3 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 ETO30597.1 - 0.0013 18.8 0.5 0.0034 17.5 0.4 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 ETO30597.1 - 0.011 15.2 1.0 0.048 13.2 0.0 2.4 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.1 ETO30597.1 - 0.13 11.7 0.1 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 EF hand Kinesin PF00225.18 ETO30598.1 - 5.8e-19 67.9 0.1 5.8e-19 67.9 0.1 2.8 2 1 0 3 3 3 1 Kinesin motor domain HALZ PF02183.13 ETO30598.1 - 0.021 14.5 0.4 0.021 14.5 0.3 4.8 6 1 1 7 7 7 0 Homeobox associated leucine zipper FMN_dh PF01070.13 ETO30601.1 - 2.7e-110 368.5 0.4 4.3e-110 367.9 0.3 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 ETO30601.1 - 3.4e-19 68.4 0.3 1.1e-18 66.7 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 ETO30601.1 - 1.2e-09 37.6 0.2 2e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 ETO30601.1 - 1.9e-06 26.9 0.6 5.7e-05 22.1 0.2 2.4 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 ETO30601.1 - 3.2e-06 26.5 0.4 1.3e-05 24.5 0.3 1.9 2 0 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.16 ETO30601.1 - 0.033 13.4 0.3 0.092 11.9 0.1 1.8 1 1 0 1 1 1 0 Histidine biosynthesis protein Peptidase_C1 PF00112.18 ETO30602.1 - 6.4e-05 22.9 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 Papain family cysteine protease zf-H2C2_2 PF13465.1 ETO30602.1 - 0.016 15.4 2.6 0.74 10.2 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger double domain Cys_rich_CPCC PF14206.1 ETO30602.1 - 0.016 14.7 1.7 0.023 14.2 0.1 2.1 3 0 0 3 3 3 0 Cysteine-rich CPCC Zn-ribbon_8 PF09723.5 ETO30602.1 - 0.11 12.4 1.0 0.38 10.7 0.7 2.0 1 0 0 1 1 1 0 Zinc ribbon domain zf-C2H2_4 PF13894.1 ETO30602.1 - 0.2 12.0 2.1 10 6.7 0.1 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 ETO30602.1 - 0.26 11.7 5.4 3.4 8.1 0.6 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2HC_2 PF13913.1 ETO30602.1 - 0.26 10.9 5.7 1.6 8.5 0.1 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-Di19 PF05605.7 ETO30602.1 - 0.37 10.9 2.0 4.7 7.3 1.4 2.3 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Auto_anti-p27 PF06677.7 ETO30602.1 - 2.6 7.8 8.0 15 5.4 3.6 3.1 2 1 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) VWA_2 PF13519.1 ETO30603.1 - 1.1e-06 28.8 0.0 0.0019 18.3 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA PF00092.23 ETO30603.1 - 4.9e-06 26.3 0.0 0.0001 22.1 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain DUF1194 PF06707.6 ETO30603.1 - 0.0011 17.9 0.0 0.0031 16.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1194) VWA_CoxE PF05762.9 ETO30603.1 - 0.014 14.5 0.0 1.5 7.8 0.0 2.2 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein VWA_3 PF13768.1 ETO30603.1 - 0.024 14.3 0.0 0.11 12.1 0.0 2.1 2 1 0 2 2 2 0 von Willebrand factor type A domain Copine PF07002.11 ETO30603.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Copine RGS PF00615.14 ETO30604.1 - 2.3e-05 24.4 1.8 0.086 12.9 0.1 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain Menin PF05053.8 ETO30605.1 - 2.7 6.0 8.9 3.7 5.6 6.2 1.3 1 0 0 1 1 1 0 Menin Exo_endo_phos PF03372.18 ETO30607.1 - 1.1e-07 32.0 0.1 2.9e-07 30.6 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TAXi_N PF14543.1 ETO30609.1 - 1.6e-13 50.9 5.0 2e-12 47.3 3.5 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal MRP-S32 PF10210.4 ETO30611.1 - 0.08 13.2 0.2 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 DUF3161 PF11362.3 ETO30612.1 - 0.11 12.4 0.1 41 4.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3161) DUF3262 PF11660.3 ETO30615.1 - 0.086 12.9 0.2 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) CCDC144C PF14915.1 ETO30616.1 - 0.12 11.2 17.3 0.076 11.9 7.7 2.1 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region HAUS5 PF14817.1 ETO30616.1 - 0.26 9.8 15.3 0.31 9.5 1.0 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 5 DUF3713 PF12506.3 ETO30616.1 - 1.8 8.6 8.1 2.3 8.3 2.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3713) bZIP_1 PF00170.16 ETO30616.1 - 2.7 7.9 15.0 1.4 8.9 0.9 3.2 2 1 1 3 3 3 0 bZIP transcription factor Ax_dynein_light PF10211.4 ETO30616.1 - 4.6 7.0 13.4 15 5.3 5.7 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain E1_dh PF00676.15 ETO30617.1 - 3.6e-53 180.2 5.6 1.5e-47 161.7 0.3 2.0 2 0 0 2 2 2 2 Dehydrogenase E1 component DUF687 PF05095.7 ETO30618.1 - 0.0043 15.4 0.1 0.0052 15.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF687) ubiquitin PF00240.18 ETO30619.1 - 9.4e-08 31.3 0.1 2e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 ETO30619.1 - 8.2e-05 22.2 0.0 0.00014 21.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Na_H_Exchanger PF00999.16 ETO30621.1 - 7e-31 107.1 8.4 8.2e-31 106.8 5.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3273 PF11677.3 ETO30621.1 - 0.05 12.8 1.7 0.085 12.1 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3273) FecCD PF01032.13 ETO30621.1 - 0.17 10.6 6.6 0.025 13.4 1.6 1.8 2 0 0 2 2 2 0 FecCD transport family EF-hand_1 PF00036.27 ETO30623.1 - 7e-13 46.8 6.6 4.4e-05 22.4 0.4 3.4 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 ETO30623.1 - 5.1e-11 42.5 5.6 5.1e-06 26.5 2.7 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO30623.1 - 5.3e-10 38.3 2.3 0.00012 21.6 0.2 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 ETO30623.1 - 4.1e-07 29.4 5.6 0.003 17.1 0.0 3.2 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 ETO30623.1 - 0.0011 18.7 5.9 0.0061 16.2 0.1 2.7 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 ETO30623.1 - 0.039 13.9 0.5 1 9.3 0.1 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.1 ETO30623.1 - 0.13 11.6 9.5 0.47 9.8 0.9 3.4 3 0 0 3 3 3 0 EF hand Neur_chan_LBD PF02931.18 ETO30624.1 - 0.058 12.5 0.0 0.15 11.2 0.0 1.7 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel ligand binding domain HDA2-3 PF11496.3 ETO30625.1 - 0.13 11.0 0.1 0.19 10.4 0.1 1.3 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 NAD_binding_1 PF00175.16 ETO30626.1 - 5.5e-26 91.2 0.0 8.1e-25 87.5 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 ETO30626.1 - 1.4e-24 86.0 0.0 2.8e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 ETO30626.1 - 1.8e-08 34.4 0.0 2.1e-06 27.7 0.0 2.7 3 0 0 3 3 3 1 Ferric reductase NAD binding domain ODV-E18 PF10717.4 ETO30626.1 - 0.012 15.0 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Rad60-SLD PF11976.3 ETO30626.1 - 0.037 13.7 1.5 0.17 11.5 0.4 2.3 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like FAD_binding_9 PF08021.6 ETO30626.1 - 0.041 13.8 0.0 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain Ost4 PF10215.4 ETO30626.1 - 0.088 12.3 0.1 0.3 10.6 0.0 1.9 2 0 0 2 2 2 0 Oligosaccaryltransferase Chordopox_A13L PF05961.6 ETO30626.1 - 0.098 12.6 0.2 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Chordopoxvirus A13L protein RhoGEF PF00621.15 ETO30627.1 - 1.9e-15 57.1 1.6 1.9e-15 57.1 1.1 1.7 2 0 0 2 2 2 1 RhoGEF domain DUF624 PF04854.9 ETO30627.1 - 0.33 10.8 2.6 0.37 10.6 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF624 LIM PF00412.17 ETO30628.1 - 2.4e-07 30.7 1.7 2.4e-07 30.7 1.2 3.5 3 1 1 4 4 3 1 LIM domain HALZ PF02183.13 ETO30628.1 - 0.00024 20.7 22.7 0.013 15.1 0.9 4.4 3 2 0 3 3 3 2 Homeobox associated leucine zipper Rootletin PF15035.1 ETO30628.1 - 0.00081 19.4 25.1 0.023 14.6 0.4 2.7 2 0 0 2 2 2 2 Ciliary rootlet component, centrosome cohesion bZIP_1 PF00170.16 ETO30628.1 - 0.0053 16.6 28.0 0.044 13.7 0.9 4.5 4 0 0 4 4 4 3 bZIP transcription factor NYD-SP28_assoc PF14775.1 ETO30628.1 - 0.027 14.1 1.7 0.027 14.1 1.2 4.4 3 1 1 4 4 4 0 Sperm tail C-terminal domain bZIP_2 PF07716.10 ETO30628.1 - 0.039 13.7 30.8 0.12 12.1 1.4 4.6 5 0 0 5 5 5 0 Basic region leucine zipper KaiC PF06745.8 ETO30628.1 - 0.29 10.2 5.2 0.31 10.1 2.3 1.8 1 1 1 2 2 2 0 KaiC Enkurin PF13864.1 ETO30628.1 - 0.98 9.6 24.7 9.2 6.5 0.8 4.2 2 1 1 3 3 3 0 Calmodulin-binding DivIC PF04977.10 ETO30628.1 - 1.8 8.1 33.0 0.29 10.6 2.3 4.7 5 1 0 5 5 5 0 Septum formation initiator DUF972 PF06156.8 ETO30628.1 - 3.7 7.9 39.1 0.92 9.8 1.9 5.0 3 1 2 5 5 5 0 Protein of unknown function (DUF972) ADIP PF11559.3 ETO30628.1 - 7.3 6.4 40.4 2.5 7.9 2.1 4.3 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding RhoGEF PF00621.15 ETO30629.1 - 2.3e-13 50.3 2.4 2.8e-13 50.1 0.4 1.8 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.24 ETO30629.1 - 1.7e-06 28.1 0.0 3.4e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 PH domain FYVE PF01363.16 ETO30629.1 - 2.8e-05 23.9 0.7 5.2e-05 23.0 0.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger DUF4078 PF13300.1 ETO30629.1 - 0.31 11.1 2.9 0.16 12.0 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4078) DUF605 PF04652.11 ETO30630.1 - 0.0031 16.9 5.8 0.0034 16.8 4.0 1.2 1 0 0 1 1 1 1 Vta1 like GAT PF03127.9 ETO30630.1 - 0.0045 16.9 0.2 0.01 15.8 0.1 1.7 1 0 0 1 1 1 1 GAT domain Mucin PF01456.12 ETO30630.1 - 0.008 15.9 22.9 0.086 12.6 4.5 2.2 2 0 0 2 2 2 2 Mucin-like glycoprotein Ribosomal_L23 PF00276.15 ETO30631.1 - 1.1e-17 63.7 1.6 3.8e-17 62.0 1.1 1.7 1 1 0 1 1 1 1 Ribosomal protein L23 TusA PF01206.12 ETO30631.1 - 0.01 15.3 0.2 0.016 14.8 0.1 1.4 1 1 0 1 1 1 0 Sulfurtransferase TusA IF-2B PF01008.12 ETO30631.1 - 0.046 12.7 0.1 0.053 12.5 0.1 1.0 1 0 0 1 1 1 0 Initiation factor 2 subunit family Cas_Cmr5 PF09701.5 ETO30631.1 - 0.074 13.2 0.0 0.093 12.9 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr5) Helicase_C PF00271.26 ETO30632.1 - 7.1e-22 77.0 0.1 6.3e-21 74.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETO30632.1 - 2.9e-06 26.9 0.2 7.9e-06 25.4 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DEAD PF00270.24 ETO30633.1 - 7.7e-06 25.4 0.1 0.0061 16.0 0.0 2.1 1 1 1 2 2 2 2 DEAD/DEAH box helicase DUF1241 PF06840.6 ETO30633.1 - 0.002 17.3 0.3 0.0032 16.7 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Ubiquitin_2 PF14560.1 ETO30633.1 - 0.063 13.5 0.2 0.1 12.8 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain AAA_11 PF13086.1 ETO30633.1 - 0.072 12.6 0.9 0.094 12.2 0.6 1.1 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 ETO30634.1 - 1.2e-07 32.0 0.1 0.0036 17.5 0.0 3.5 3 1 0 3 3 3 2 ABC transporter SMC_N PF02463.14 ETO30634.1 - 0.0082 15.3 0.0 0.018 14.2 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain FimP PF09766.4 ETO30637.1 - 0.22 10.5 8.4 0.017 14.2 2.4 1.6 2 0 0 2 2 2 0 Fms-interacting protein Tim54 PF11711.3 ETO30637.1 - 2.1 6.8 8.2 3.4 6.1 5.7 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Retinal PF15449.1 ETO30638.1 - 0.37 8.4 7.3 0.42 8.2 5.1 1.0 1 0 0 1 1 1 0 Retinal protein Ham1p_like PF01725.11 ETO30639.1 - 3.1e-46 157.1 0.0 3.6e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Ham1 family AA_permease PF00324.16 ETO30640.1 - 1.8e-51 175.0 31.4 5.1e-31 107.5 12.5 2.2 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 ETO30640.1 - 1.5e-14 53.3 33.7 1.1e-12 47.2 12.4 2.5 1 1 1 2 2 2 2 Amino acid permease Zip PF02535.17 ETO30640.1 - 0.0002 20.4 3.9 0.0002 20.4 2.7 1.9 2 0 0 2 2 2 1 ZIP Zinc transporter ETRAMP PF09716.5 ETO30640.1 - 0.21 11.5 7.6 0.16 11.9 2.6 2.9 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) TRAP_alpha PF03896.11 ETO30640.1 - 1.7 7.6 11.1 0.96 8.3 5.8 1.9 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF1510 PF07423.6 ETO30640.1 - 1.7 7.9 30.5 0.15 11.4 16.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) GTSE1_N PF15259.1 ETO30641.1 - 0.046 13.6 0.2 0.046 13.6 0.2 1.8 2 0 0 2 2 2 0 G-2 and S-phase expressed 1 DUF4361 PF14274.1 ETO30641.1 - 0.55 9.8 6.8 0.64 9.6 0.3 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4361) Pkinase PF00069.20 ETO30642.1 - 1.4e-50 171.8 0.0 6.4e-48 163.1 0.0 2.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO30642.1 - 1.7e-21 76.5 0.0 8.2e-10 38.1 0.0 2.8 1 1 1 2 2 2 2 Protein tyrosine kinase FeoB_N PF02421.13 ETO30642.1 - 0.021 14.0 0.1 0.042 13.1 0.1 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B EMG1 PF03587.9 ETO30643.1 - 0.026 13.8 0.4 0.027 13.7 0.3 1.1 1 0 0 1 1 1 0 EMG1/NEP1 methyltransferase FUN14 PF04930.10 ETO30643.1 - 0.2 11.9 1.1 0.29 11.4 0.8 1.2 1 0 0 1 1 1 0 FUN14 family Pox_polyA_pol_N PF12630.2 ETO30643.1 - 0.27 11.3 9.4 0.34 11.0 6.5 1.2 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase N-terminal domain Membr_traf_MHD PF10540.4 ETO30644.1 - 0.09 12.5 3.5 0.13 12.0 2.4 1.2 1 0 0 1 1 1 0 Munc13 (mammalian uncoordinated) homology domain Thioredoxin_4 PF13462.1 ETO30645.1 - 0.13 12.3 1.0 0.21 11.5 0.6 1.5 1 1 0 1 1 1 0 Thioredoxin MIP-T3 PF10243.4 ETO30646.1 - 4.3e-07 28.7 120.8 1.5e-05 23.6 22.8 2.2 2 0 0 2 2 2 2 Microtubule-binding protein MIP-T3 Dicty_REP PF05086.7 ETO30646.1 - 0.00057 17.8 25.2 0.00057 17.8 17.4 3.4 2 1 1 3 3 3 1 Dictyostelium (Slime Mold) REP protein DUF1632 PF07857.7 ETO30647.1 - 0.0025 17.0 0.2 0.0025 17.0 0.2 3.1 2 2 1 3 3 3 1 CEO family (DUF1632) Zip PF02535.17 ETO30647.1 - 0.0063 15.5 26.3 0.044 12.8 6.7 2.5 2 0 0 2 2 2 2 ZIP Zinc transporter ETRAMP PF09716.5 ETO30647.1 - 0.032 14.1 0.9 0.032 14.1 0.6 4.2 2 2 1 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) DUF4010 PF13194.1 ETO30647.1 - 0.15 11.3 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) DUF1777 PF08648.7 ETO30647.1 - 3.2 7.4 88.0 0.61 9.7 29.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) WD40 PF00400.27 ETO30649.1 - 9.4e-36 120.4 9.5 2.3e-12 46.2 0.3 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO30649.1 - 3.9e-07 29.9 5.2 0.022 14.9 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 ETO30649.1 - 6.3e-06 25.8 5.4 0.0096 15.6 0.0 4.8 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO30649.1 - 0.00016 21.1 9.3 0.034 13.6 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO30649.1 - 0.00041 20.4 0.4 0.14 12.3 0.0 3.8 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO30649.1 - 0.00042 20.1 2.5 0.036 14.0 0.3 3.6 4 0 0 4 4 4 1 Kelch motif WD40 PF00400.27 ETO30650.1 - 3.6e-19 67.8 0.6 2.7e-07 30.1 0.0 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO30650.1 - 0.0023 16.1 0.4 0.0066 14.6 0.1 1.8 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO30650.1 - 0.01 14.6 0.9 0.022 13.5 0.4 1.7 1 1 0 1 1 1 0 Nup133 N terminal like Mito_carr PF00153.22 ETO30651.1 - 0.0033 17.1 4.9 0.02 14.5 1.1 2.5 2 1 0 2 2 2 2 Mitochondrial carrier protein SSV1_ORF_D-335 PF07935.6 ETO30652.1 - 0.016 14.9 0.7 0.05 13.3 0.5 1.9 1 0 0 1 1 1 0 ORF D-335-like protein eIF-3c_N PF05470.7 ETO30653.1 - 0.065 11.3 10.8 0.08 11.0 7.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Mitofilin PF09731.4 ETO30653.1 - 0.085 11.5 11.8 0.089 11.4 8.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Exonuc_VII_L PF02601.10 ETO30653.1 - 0.13 11.4 6.9 0.15 11.2 4.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3276 PF11680.3 ETO30653.1 - 0.16 11.7 11.4 0.051 13.3 6.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3276) Borrelia_P83 PF05262.6 ETO30653.1 - 0.18 10.0 10.8 0.19 9.9 7.5 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Rotamase PF00639.16 ETO30653.1 - 0.21 12.3 5.0 0.3 11.8 2.5 1.9 1 1 1 2 2 2 0 PPIC-type PPIASE domain RAP1 PF07218.6 ETO30653.1 - 0.26 9.3 8.8 0.29 9.2 6.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SET PF00856.23 ETO30653.1 - 0.3 11.3 2.1 0.35 11.1 1.5 1.2 1 0 0 1 1 1 0 SET domain Spore_coat_CotO PF14153.1 ETO30653.1 - 0.41 10.0 14.0 0.49 9.7 9.7 1.3 1 0 0 1 1 1 0 Spore coat protein CotO FAM176 PF14851.1 ETO30653.1 - 0.59 9.8 4.7 0.88 9.2 3.3 1.4 1 0 0 1 1 1 0 FAM176 family GAGA_bind PF06217.7 ETO30653.1 - 0.66 9.8 11.0 0.75 9.7 7.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DDHD PF02862.12 ETO30653.1 - 1.1 9.0 7.2 1.3 8.8 5.0 1.3 1 0 0 1 1 1 0 DDHD domain RNase_H2-Ydr279 PF09468.5 ETO30653.1 - 1.8 7.6 10.1 2.4 7.2 7.0 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) IncA PF04156.9 ETO30653.1 - 3.7 7.0 9.0 4.2 6.9 6.3 1.2 1 0 0 1 1 1 0 IncA protein DUF3987 PF13148.1 ETO30653.1 - 7.9 4.9 10.7 9.4 4.6 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) SseC PF04888.7 ETO30653.1 - 9.8 5.4 9.0 15 4.8 6.2 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Mucin PF01456.12 ETO30655.1 - 0.028 14.1 11.6 0.11 12.2 8.1 2.0 1 1 0 1 1 1 0 Mucin-like glycoprotein PBP_sp32 PF07222.7 ETO30655.1 - 4 6.5 24.0 2.2 7.4 4.8 2.5 2 1 1 3 3 3 0 Proacrosin binding protein sp32 AAA PF00004.24 ETO30657.1 - 1.4e-09 38.1 0.1 7.8e-06 26.1 0.0 3.5 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETO30657.1 - 4.2e-07 29.7 0.0 0.0015 18.2 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETO30657.1 - 1e-05 25.6 0.1 0.019 15.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain DUF815 PF05673.8 ETO30657.1 - 0.0006 18.8 0.2 0.003 16.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 ETO30657.1 - 0.0014 18.5 3.2 0.0066 16.3 0.0 3.2 3 1 0 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.1 ETO30657.1 - 0.0023 17.9 0.1 0.18 11.8 0.0 3.3 3 1 1 4 4 4 1 Sigma-54 interaction domain MCM PF00493.18 ETO30657.1 - 0.0028 16.4 0.8 0.38 9.4 0.0 3.4 4 0 0 4 4 4 1 MCM2/3/5 family IstB_IS21 PF01695.12 ETO30657.1 - 0.0032 16.9 0.3 0.12 11.7 0.0 3.1 3 0 0 3 3 3 1 IstB-like ATP binding protein PduV-EutP PF10662.4 ETO30657.1 - 0.0043 16.5 1.3 0.049 13.1 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.7 ETO30657.1 - 0.0045 16.1 0.0 0.19 10.8 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin DUF258 PF03193.11 ETO30657.1 - 0.0049 16.0 0.0 0.018 14.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 ETO30657.1 - 0.0063 16.5 0.5 0.37 10.7 0.1 3.0 2 1 1 3 3 3 1 AAA ATPase domain ABC_tran PF00005.22 ETO30657.1 - 0.011 16.0 4.7 0.013 15.7 0.0 3.1 4 0 0 4 4 4 0 ABC transporter Sigma54_activat PF00158.21 ETO30657.1 - 0.015 14.7 0.1 0.31 10.4 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 ETO30657.1 - 0.031 13.4 0.4 10 5.2 0.0 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 ETO30657.1 - 0.045 13.9 0.0 2.2 8.4 0.0 2.9 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.7 ETO30657.1 - 0.058 13.0 3.7 0.73 9.4 0.0 3.7 3 1 0 4 4 4 0 NACHT domain AAA_25 PF13481.1 ETO30657.1 - 0.059 12.7 0.1 16 4.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain T2SE PF00437.15 ETO30657.1 - 0.087 11.7 0.3 2.2 7.1 0.0 2.4 2 1 0 2 2 2 0 Type II/IV secretion system protein Peptidase_S49_N PF08496.5 ETO30657.1 - 0.098 12.4 2.7 0.26 11.0 1.9 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal AAA_21 PF13304.1 ETO30657.1 - 0.11 12.4 2.3 1.2 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 ETO30657.1 - 0.11 11.9 0.1 0.69 9.3 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Arch_ATPase PF01637.13 ETO30657.1 - 0.25 11.0 0.1 0.25 11.0 0.1 3.1 2 1 1 3 3 3 0 Archaeal ATPase TPP_enzyme_C PF02775.16 ETO30658.1 - 7.6e-19 67.7 0.1 1.6e-18 66.7 0.0 1.6 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 ETO30658.1 - 0.12 11.3 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Pox_Ag35 PF03286.9 ETO30659.1 - 0.0021 17.5 7.6 0.056 12.9 2.9 2.1 2 0 0 2 2 2 2 Pox virus Ag35 surface protein Gag_spuma PF03276.9 ETO30659.1 - 0.2 9.9 2.7 0.28 9.4 1.9 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Presenilin PF01080.12 ETO30659.1 - 0.31 9.8 1.9 0.49 9.1 1.3 1.2 1 0 0 1 1 1 0 Presenilin Peptidase_S49_N PF08496.5 ETO30659.1 - 0.76 9.5 4.5 0.41 10.4 1.2 1.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal FLO_LFY PF01698.11 ETO30659.1 - 5.9 5.6 9.9 0.29 9.9 3.1 1.5 2 0 0 2 2 2 0 Floricaula / Leafy protein Kelch_6 PF13964.1 ETO30660.1 - 0.00028 20.9 5.5 1.3 9.3 0.0 4.5 4 1 1 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO30660.1 - 0.01 15.5 9.5 4.9 7.0 0.1 5.3 5 1 0 5 5 5 0 Kelch motif Kelch_4 PF13418.1 ETO30660.1 - 0.072 12.8 3.0 7.5 6.4 0.1 3.7 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO30660.1 - 0.47 10.0 10.1 4.5 6.9 0.0 4.6 5 0 0 5 5 5 0 Kelch motif NikR_C PF08753.6 ETO30661.1 - 0.0071 16.2 1.1 0.0071 16.2 0.7 2.2 2 0 0 2 2 2 1 NikR C terminal nickel binding domain GP46 PF07409.7 ETO30661.1 - 0.079 12.2 0.0 0.32 10.3 0.0 2.0 2 0 0 2 2 2 0 Phage protein GP46 DUF3349 PF11829.3 ETO30661.1 - 0.12 12.7 1.2 1.7 9.1 0.0 3.3 4 1 0 4 4 4 0 Protein of unknown function (DUF3349) CDC45 PF02724.9 ETO30663.1 - 0.042 11.8 6.6 0.05 11.6 4.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.11 ETO30663.1 - 0.13 12.1 0.3 0.22 11.3 0.2 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RNA_GG_bind PF10258.4 ETO30663.1 - 0.13 12.0 0.5 0.7 9.6 0.2 2.0 2 0 0 2 2 2 0 PHAX RNA-binding domain BSP_II PF05432.6 ETO30663.1 - 0.43 9.8 15.3 0.86 8.8 10.4 1.6 1 1 0 1 1 1 0 Bone sialoprotein II (BSP-II) Daxx PF03344.10 ETO30663.1 - 0.9 7.9 13.8 1 7.7 9.5 1.1 1 0 0 1 1 1 0 Daxx Family CobU PF02283.11 ETO30663.1 - 1.8 7.9 4.6 0.62 9.4 0.1 2.0 1 1 1 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AMMECR1 PF01871.12 ETO30664.1 - 0.0036 16.4 0.2 0.0083 15.2 0.0 1.7 2 0 0 2 2 2 1 AMMECR1 SDA1 PF05285.7 ETO30664.1 - 0.0046 16.2 23.5 0.0084 15.4 16.3 1.3 1 0 0 1 1 1 1 SDA1 Daxx PF03344.10 ETO30664.1 - 0.95 7.8 20.7 1.2 7.5 14.4 1.2 1 0 0 1 1 1 0 Daxx Family WD40 PF00400.27 ETO30665.1 - 6e-80 260.5 8.1 1.2e-11 43.9 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO30665.1 - 5.6e-08 31.3 5.9 0.037 12.1 0.1 5.0 2 2 2 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO30665.1 - 0.00014 20.7 6.2 1.2 7.8 0.1 4.7 1 1 3 4 4 4 3 Nup133 N terminal like PD40 PF07676.7 ETO30665.1 - 0.0013 18.3 1.0 25 4.6 0.0 5.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO30665.1 - 0.0022 16.3 1.1 0.41 8.8 0.1 2.9 2 1 1 3 3 3 3 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO30665.1 - 0.0037 16.4 0.5 11 4.9 0.0 3.7 1 1 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal FmdE PF02663.9 ETO30665.1 - 0.1 12.5 0.3 0.62 9.9 0.0 2.4 2 1 1 3 3 3 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Drf_FH3 PF06367.11 ETO30666.1 - 0.0013 18.1 1.4 0.0021 17.4 0.2 1.8 2 0 0 2 2 2 1 Diaphanous FH3 Domain CTK3 PF12243.3 ETO30666.1 - 0.066 12.8 4.1 1.3 8.6 0.1 2.3 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 Phage_GP20 PF06810.6 ETO30667.1 - 3.6 7.0 39.3 0.44 9.9 16.9 3.5 1 1 2 3 3 3 0 Phage minor structural protein GP20 TSA PF03249.8 ETO30668.1 - 0.03 12.8 2.9 0.038 12.5 2.0 1.1 1 0 0 1 1 1 0 Type specific antigen Dicty_REP PF05086.7 ETO30669.1 - 0.058 11.1 10.5 0.098 10.4 7.3 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4611 PF15387.1 ETO30669.1 - 0.54 10.4 10.8 2.7 8.2 4.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Sigma70_ner PF04546.8 ETO30669.1 - 8 6.0 13.7 4 7.0 6.3 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 ETO30669.1 - 8.6 5.8 11.7 4.3 6.8 3.1 2.7 3 0 0 3 3 3 0 Nucleoplasmin DUF349 PF03993.7 ETO30671.1 - 0.0075 16.4 2.5 0.0075 16.4 1.7 2.3 2 1 0 2 2 2 1 Domain of Unknown Function (DUF349) 60KD_IMP PF02096.15 ETO30672.1 - 5.6e-15 55.5 0.2 5.6e-15 55.5 0.1 1.8 2 0 0 2 2 2 1 60Kd inner membrane protein Mis12 PF05859.7 ETO30672.1 - 0.072 12.8 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Mis12 protein Holin_BlyA PF05102.7 ETO30675.1 - 0.28 10.9 4.2 0.48 10.1 0.3 2.8 2 0 0 2 2 2 0 holin, BlyA family PA26 PF04636.8 ETO30677.1 - 0.15 10.6 5.3 0.17 10.5 3.7 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Sod_Ni PF09055.6 ETO30677.1 - 0.16 12.3 1.8 0.23 11.8 1.2 1.3 1 0 0 1 1 1 0 Nickel-containing superoxide dismutase FLO_LFY PF01698.11 ETO30677.1 - 0.18 10.5 8.5 0.22 10.3 5.9 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein MMR1 PF08505.5 ETO30677.1 - 0.86 9.5 13.1 0.98 9.4 9.1 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein TMV_coat PF00721.16 ETO30677.1 - 1.5 8.7 6.7 0.4 10.5 2.4 1.9 1 1 1 2 2 2 0 Virus coat protein (TMV like) DUF3603 PF12227.3 ETO30678.1 - 0.014 14.5 0.4 0.016 14.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3603) Plasmid_parti PF01672.11 ETO30678.1 - 0.018 15.4 1.4 0.032 14.6 1.0 1.4 1 0 0 1 1 1 0 Putative plasmid partition protein PhnI PF05861.7 ETO30681.1 - 0.0051 15.3 0.0 0.0056 15.2 0.0 1.0 1 0 0 1 1 1 1 Bacterial phosphonate metabolism protein (PhnI) DUF4023 PF13215.1 ETO30681.1 - 0.0053 16.5 0.8 0.0076 16.0 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4023) GCR1_C PF12550.3 ETO30682.1 - 0.011 15.5 0.1 0.034 14.0 0.0 1.8 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes bZIP_1 PF00170.16 ETO30682.1 - 0.074 13.0 0.6 0.16 11.9 0.4 1.6 1 0 0 1 1 1 0 bZIP transcription factor ABC_tran PF00005.22 ETO30683.1 - 9.4e-05 22.7 0.0 0.0013 19.0 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_5 PF07728.9 ETO30683.1 - 0.00015 21.5 0.0 0.00032 20.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Miro PF08477.8 ETO30683.1 - 0.0013 19.2 0.1 0.0076 16.7 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein AAA PF00004.24 ETO30683.1 - 0.0016 18.6 0.0 0.0039 17.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 ETO30683.1 - 0.0041 16.3 0.0 0.0081 15.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 ETO30683.1 - 0.0071 16.0 0.3 0.062 12.9 0.0 2.6 3 0 0 3 3 3 1 Archaeal ATPase SecA_DEAD PF07517.9 ETO30683.1 - 0.0087 15.3 0.2 0.035 13.4 0.0 2.1 1 1 1 2 2 2 1 SecA DEAD-like domain AAA_22 PF13401.1 ETO30683.1 - 0.0093 16.1 0.0 0.025 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 ETO30683.1 - 0.033 14.0 0.0 0.15 11.9 0.0 2.2 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 ETO30683.1 - 0.076 13.0 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain ATP-synt_ab PF00006.20 ETO30683.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Kinesin PF00225.18 ETO30684.1 - 9.9e-61 205.2 1.0 9.9e-61 205.2 0.7 3.1 2 2 1 3 3 3 1 Kinesin motor domain adh_short PF00106.20 ETO30686.1 - 2.9e-20 72.8 1.7 1.4e-19 70.6 1.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETO30686.1 - 7.7e-14 52.0 1.0 1.2e-13 51.4 0.7 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETO30686.1 - 1.2e-06 28.2 1.3 3.8e-06 26.7 0.1 2.0 2 0 0 2 2 2 1 KR domain SRRM_C PF15230.1 ETO30686.1 - 0.048 13.7 1.4 0.096 12.7 1.0 1.4 1 0 0 1 1 1 0 Serine/arginine repetitive matrix protein C-terminus PUF PF00806.14 ETO30687.1 - 4.8e-44 145.4 19.0 2.1e-07 30.0 0.3 8.7 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Lebercilin PF15619.1 ETO30688.1 - 0.0034 16.8 1.2 0.0052 16.2 0.8 1.2 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Fib_alpha PF08702.5 ETO30688.1 - 0.11 12.6 1.0 0.2 11.8 0.7 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DivIC PF04977.10 ETO30688.1 - 0.18 11.2 2.8 0.35 10.3 1.0 2.0 2 0 0 2 2 2 0 Septum formation initiator DUF4407 PF14362.1 ETO30688.1 - 0.22 10.4 0.4 0.36 9.7 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_1 PF00170.16 ETO30688.1 - 0.47 10.4 3.1 0.84 9.6 2.2 1.4 1 0 0 1 1 1 0 bZIP transcription factor NIF PF03031.13 ETO30689.1 - 5.6e-08 32.6 0.2 6.9e-08 32.3 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Sec7 PF01369.15 ETO30690.1 - 3.6e-27 95.2 0.0 3.6e-27 95.2 0.0 2.8 2 0 0 2 2 2 1 Sec7 domain DUF2464 PF10240.4 ETO30690.1 - 7.3e-06 25.5 0.0 7.3e-06 25.5 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2464) Sec7_N PF12783.2 ETO30690.1 - 0.00033 20.1 10.7 0.0068 15.8 0.0 3.8 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal FYVE_2 PF02318.11 ETO30691.1 - 3.4e-06 26.9 7.6 5.1e-06 26.3 5.2 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger ZZ PF00569.12 ETO30691.1 - 1 8.9 14.9 0.46 10.0 7.1 2.6 2 0 0 2 2 2 0 Zinc finger, ZZ type PHBC_N PF12551.3 ETO30692.1 - 0.00073 19.0 0.1 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Poly-beta-hydroxybutyrate polymerase N terminal DegS PF05384.6 ETO30692.1 - 0.0011 18.2 3.5 0.0011 18.2 2.4 3.1 2 1 1 3 3 3 1 Sensor protein DegS Tropomyosin_1 PF12718.2 ETO30692.1 - 0.0027 17.5 24.3 0.0027 17.5 16.9 2.4 2 1 0 2 2 2 1 Tropomyosin like Uds1 PF15456.1 ETO30692.1 - 0.0033 17.3 11.0 0.0033 17.3 7.6 2.8 2 1 1 3 3 3 1 Up-regulated During Septation TPR_MLP1_2 PF07926.7 ETO30692.1 - 0.0048 16.6 11.2 0.0048 16.6 7.8 3.2 2 1 1 3 3 3 1 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 ETO30692.1 - 0.0071 15.3 22.5 0.19 10.6 1.4 2.4 1 1 1 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 DUF885 PF05960.6 ETO30692.1 - 0.0085 15.2 2.3 0.01 15.0 1.6 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) Laminin_II PF06009.7 ETO30692.1 - 0.01 15.5 19.0 0.07 12.8 1.6 2.7 2 1 1 3 3 3 0 Laminin Domain II AAA_13 PF13166.1 ETO30692.1 - 0.013 13.9 18.0 0.021 13.3 12.5 1.4 1 1 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 ETO30692.1 - 0.02 14.0 4.8 0.029 13.5 0.6 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein PMEI PF04043.10 ETO30692.1 - 0.067 13.0 5.6 0.27 11.1 2.7 2.1 1 1 1 2 2 2 0 Plant invertase/pectin methylesterase inhibitor DUF4200 PF13863.1 ETO30692.1 - 0.22 11.4 36.7 1.3 8.9 9.4 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) DUF3584 PF12128.3 ETO30692.1 - 0.29 8.4 27.5 0.0099 13.2 13.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) IncA PF04156.9 ETO30692.1 - 1 8.9 37.3 0.55 9.7 12.2 3.0 2 1 1 3 3 3 0 IncA protein CALCOCO1 PF07888.6 ETO30692.1 - 2.3 6.4 23.2 0.029 12.6 10.7 1.7 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Rootletin PF15035.1 ETO30692.1 - 2.3 8.1 29.9 3.6 7.5 2.1 2.9 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Spc7 PF08317.6 ETO30692.1 - 2.7 6.5 29.2 0.019 13.6 14.5 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein Phage_GP20 PF06810.6 ETO30692.1 - 2.8 7.3 30.8 0.27 10.6 2.1 3.3 2 1 1 3 3 3 0 Phage minor structural protein GP20 FliD_N PF02465.13 ETO30692.1 - 3.1 8.1 16.2 18 5.7 0.2 3.7 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus SlyX PF04102.7 ETO30692.1 - 3.6 8.0 21.7 3.2 8.2 0.1 5.3 2 1 3 5 5 4 0 SlyX PerC PF06069.6 ETO30692.1 - 4.6 7.3 6.5 34 4.5 0.8 3.3 3 1 0 3 3 3 0 PerC transcriptional activator Tropomyosin PF00261.15 ETO30692.1 - 7.3 5.6 32.5 0.27 10.3 16.9 2.3 2 1 0 2 2 2 0 Tropomyosin Flagellin_N PF00669.15 ETO30692.1 - 8.7 6.1 12.2 4.1 7.2 3.0 3.0 2 1 0 2 2 2 0 Bacterial flagellin N-terminal helical region Evr1_Alr PF04777.8 ETO30692.1 - 9.5 6.1 7.9 1.6 8.6 0.9 2.5 2 1 1 3 3 3 0 Erv1 / Alr family DSPc PF00782.15 ETO30693.1 - 3.1e-05 23.5 0.2 3.1e-05 23.5 0.1 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain CDC73 PF05179.9 ETO30693.1 - 0.021 14.1 6.6 0.031 13.6 4.6 1.3 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family Menin PF05053.8 ETO30693.1 - 0.14 10.2 4.0 0.18 9.9 2.8 1.1 1 0 0 1 1 1 0 Menin Macoilin PF09726.4 ETO30693.1 - 5.9 5.0 19.7 7.2 4.7 13.6 1.1 1 0 0 1 1 1 0 Transmembrane protein EIF_2_alpha PF07541.7 ETO30694.1 - 0.039 13.6 0.8 0.051 13.2 0.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit DUF359 PF04019.7 ETO30694.1 - 0.047 13.0 1.0 0.067 12.5 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF359) DUF2815 PF10991.3 ETO30694.1 - 0.4 10.1 7.4 0.47 9.9 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2815) PMSR PF01625.16 ETO30694.1 - 1 9.1 6.4 1.4 8.8 4.4 1.2 1 0 0 1 1 1 0 Peptide methionine sulfoxide reductase A_deamin PF02137.13 ETO30694.1 - 1.2 8.3 8.5 1.3 8.2 5.9 1.0 1 0 0 1 1 1 0 Adenosine-deaminase (editase) domain Menin PF05053.8 ETO30694.1 - 4.6 5.2 11.8 5.1 5.1 8.2 1.0 1 0 0 1 1 1 0 Menin DUF908 PF06012.7 ETO30694.1 - 8.4 5.5 9.7 9.1 5.4 6.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) WD40 PF00400.27 ETO30695.1 - 5.9e-72 235.1 13.4 3.4e-12 45.7 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO30695.1 - 9.3e-08 30.6 0.6 0.072 11.2 0.0 3.6 1 1 2 3 3 3 3 Nucleoporin Nup120/160 DUF1258 PF06869.7 ETO30695.1 - 0.0018 17.3 0.7 0.026 13.6 0.1 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF1258) PD40 PF07676.7 ETO30695.1 - 0.0044 16.6 11.1 1.4 8.7 0.1 5.7 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO30695.1 - 0.011 14.0 0.9 0.99 7.6 0.1 2.8 1 1 1 2 2 2 0 Cytochrome D1 heme domain Resistin PF06954.6 ETO30695.1 - 0.013 15.7 1.3 28 5.0 0.0 4.6 3 2 2 5 5 5 0 Resistin DUF3732 PF12532.3 ETO30695.1 - 0.25 10.8 5.3 18 4.7 0.0 4.2 5 1 1 6 6 6 0 Protein of unknown function (DUF3732) STAS PF01740.16 ETO30696.1 - 2.8e-23 81.5 0.1 4.8e-23 80.8 0.1 1.3 1 0 0 1 1 1 1 STAS domain Sulfate_transp PF00916.15 ETO30696.1 - 3.3e-20 72.2 0.1 5.4e-20 71.5 0.1 1.3 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_transp PF00916.15 ETO30697.1 - 4.5e-16 58.6 2.9 6e-16 58.2 2.0 1.1 1 0 0 1 1 1 1 Sulfate transporter family DUF3802 PF12290.3 ETO30699.1 - 0.051 13.8 0.0 0.058 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3802) Scm3 PF10384.4 ETO30700.1 - 0.078 12.4 0.6 0.2 11.1 0.4 1.6 1 0 0 1 1 1 0 Centromere protein Scm3 ASL_C PF08328.6 ETO30701.1 - 0.049 13.4 0.7 0.067 13.0 0.5 1.2 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal tRNA_synt_1c_R2 PF04557.10 ETO30701.1 - 0.057 14.1 1.3 0.083 13.5 0.9 1.3 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Vfa1 PF08432.5 ETO30701.1 - 0.22 11.5 5.9 0.25 11.3 4.1 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1980 PF09323.5 ETO30701.1 - 0.75 9.5 4.8 0.88 9.2 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) HSBP1 PF06825.7 ETO30701.1 - 5.2 6.7 8.5 11 5.7 3.9 2.4 1 1 1 2 2 2 0 Heat shock factor binding protein 1 DUF2263 PF10021.4 ETO30702.1 - 2.4e-24 86.0 0.2 2.2e-23 82.9 0.0 2.3 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2263) PARG_cat PF05028.9 ETO30702.1 - 0.0045 16.2 0.0 0.0045 16.2 0.0 2.3 2 1 1 3 3 3 1 Poly (ADP-ribose) glycohydrolase (PARG) DUF3114 PF11311.3 ETO30702.1 - 0.018 14.4 0.3 0.03 13.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3114) DUF4613 PF15390.1 ETO30702.1 - 0.019 13.1 4.7 0.008 14.4 1.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4613) TPR_12 PF13424.1 ETO30703.1 - 3.2e-60 200.0 9.9 6e-20 70.9 0.3 4.3 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETO30703.1 - 2e-41 139.4 37.8 6.7e-14 51.2 1.0 4.5 1 1 4 5 5 5 5 TPR repeat TPR_1 PF00515.23 ETO30703.1 - 1.1e-34 116.6 26.4 4.3e-08 32.4 0.3 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 ETO30703.1 - 2.4e-32 108.2 34.7 1.8e-06 27.2 0.3 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.1 ETO30703.1 - 4.5e-29 97.9 2.5 2.8e-05 23.5 0.0 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETO30703.1 - 2.2e-27 92.7 17.6 2.6e-05 23.7 0.1 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETO30703.1 - 1.2e-26 91.7 0.0 1.9e-06 27.6 0.0 6.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 ETO30703.1 - 6.5e-14 50.9 11.9 0.012 15.7 0.1 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 ETO30703.1 - 1.5e-11 44.4 0.3 0.0016 18.7 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO30703.1 - 1.1e-09 38.1 9.0 1.4 9.5 0.0 6.8 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO30703.1 - 1.4e-09 37.7 0.0 5.3 7.9 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO30703.1 - 2.7e-09 37.0 13.1 5.8e-05 23.1 3.0 3.9 1 1 3 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 ETO30703.1 - 4e-09 36.9 0.0 0.26 11.9 0.0 4.5 2 1 2 4 4 4 3 Tetratricopeptide repeat DUF2225 PF09986.4 ETO30703.1 - 4.8e-05 22.9 9.3 0.15 11.5 2.3 3.8 1 1 2 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) mit_SMPDase PF14724.1 ETO30703.1 - 0.0011 16.8 1.7 0.051 11.3 0.1 2.4 1 1 2 3 3 3 1 Mitochondrial-associated sphingomyelin phosphodiesterase MIT PF04212.13 ETO30703.1 - 0.0013 18.5 5.3 0.16 11.8 0.1 4.3 4 1 0 4 4 4 1 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.4 ETO30703.1 - 0.0019 17.4 0.2 0.85 8.9 0.0 4.1 4 0 0 4 4 4 1 SHNi-TPR PPR PF01535.15 ETO30703.1 - 0.0037 17.1 0.3 1.6 8.8 0.0 4.4 5 0 0 5 5 5 1 PPR repeat DUF627 PF04781.7 ETO30703.1 - 0.037 13.6 8.6 0.48 10.0 1.6 3.8 2 1 2 4 4 4 0 Protein of unknown function (DUF627) TPR_3 PF07720.7 ETO30703.1 - 0.22 11.3 21.4 0.93 9.3 0.1 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat SPASM PF13186.1 ETO30703.1 - 0.26 11.6 1.4 7.3 7.0 0.0 3.3 3 0 0 3 3 2 0 Iron-sulfur cluster-binding domain Borrelia_orfD PF02999.9 ETO30704.1 - 0.047 13.8 0.7 0.047 13.8 0.5 1.9 2 0 0 2 2 2 0 Borrelia orf-D family WD40 PF00400.27 ETO30705.1 - 3.3e-59 194.7 18.8 1.9e-10 40.2 0.5 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO30705.1 - 3.3e-10 38.7 4.0 0.018 13.1 0.1 5.1 1 1 5 6 6 6 5 Nucleoporin Nup120/160 Methyltransf_25 PF13649.1 ETO30705.1 - 0.0076 16.5 0.0 1 9.7 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain DUF1900 PF08954.6 ETO30705.1 - 0.033 13.6 0.0 2.9 7.4 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF1900) WD40 PF00400.27 ETO30706.1 - 5.7e-67 219.3 11.6 1.3e-12 47.0 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO30706.1 - 7.8e-16 58.3 0.3 4e-05 23.4 0.0 3.3 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO30706.1 - 1e-09 37.1 9.2 0.011 13.9 0.0 4.7 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO30706.1 - 3.9e-06 25.8 5.6 0.61 8.7 0.1 4.2 2 2 2 4 4 4 3 Nup133 N terminal like Nbas_N PF15492.1 ETO30706.1 - 1.5e-05 24.2 2.0 1.2 8.2 0.1 4.3 1 1 4 5 5 5 3 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 ETO30706.1 - 2e-05 23.0 0.1 0.12 10.6 0.0 3.3 1 1 3 4 4 4 3 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO30706.1 - 7.1e-05 22.3 0.3 0.0015 18.0 0.0 2.6 1 1 0 1 1 1 1 PQQ-like domain Hira PF07569.6 ETO30706.1 - 0.00059 19.1 0.3 3 7.0 0.0 3.6 3 1 1 4 4 4 2 TUP1-like enhancer of split PD40 PF07676.7 ETO30706.1 - 0.0011 18.5 15.7 5.6 6.7 0.1 6.6 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat SGL PF08450.7 ETO30706.1 - 0.003 16.9 0.1 0.012 14.9 0.0 1.9 2 0 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Ricin_B_lectin PF00652.17 ETO30706.1 - 0.014 15.4 1.4 0.74 9.8 0.1 2.8 2 2 0 2 2 2 0 Ricin-type beta-trefoil lectin domain DPPIV_N PF00930.16 ETO30706.1 - 0.021 13.4 0.1 16 3.9 0.0 3.8 2 1 2 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF1914 PF08932.5 ETO30706.1 - 0.026 14.5 3.7 24 5.0 0.0 4.7 2 2 2 5 5 5 0 Domain of unknown function (DUF1914) Proteasome_A_N PF10584.4 ETO30706.1 - 7.1 6.0 11.8 40 3.6 0.0 5.2 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature DUF4083 PF13314.1 ETO30707.1 - 0.71 9.7 3.0 0.42 10.4 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) FAD_binding_3 PF01494.14 ETO30708.1 - 0.013 14.5 0.0 0.017 14.1 0.0 1.0 1 0 0 1 1 1 0 FAD binding domain YqgF PF14639.1 ETO30709.1 - 0.056 13.0 1.0 0.069 12.7 0.2 1.6 1 1 1 2 2 2 0 Holliday-junction resolvase-like of SPT6 UPF0449 PF15136.1 ETO30709.1 - 1.4 9.1 8.5 0.14 12.4 0.9 2.2 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 GH97_C PF14509.1 ETO30709.1 - 2 8.5 5.2 3.6 7.7 0.3 2.1 1 1 1 2 2 2 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation DBP10CT PF08147.7 ETO30709.1 - 2.6 7.9 11.2 0.25 11.1 3.5 2.3 1 1 1 2 2 2 0 DBP10CT (NUC160) domain bZIP_1 PF00170.16 ETO30710.1 - 0.064 13.2 1.4 0.2 11.6 1.0 1.8 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.10 ETO30710.1 - 0.21 11.4 5.8 0.06 13.1 1.7 1.8 2 0 0 2 2 2 0 Basic region leucine zipper Zn_Tnp_IS1595 PF12760.2 ETO30712.1 - 0.014 15.2 2.5 0.027 14.2 1.7 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DUF4441 PF14536.1 ETO30712.1 - 0.66 9.9 13.5 7.6 6.5 9.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4441) Bacillus_HBL PF05791.6 ETO30713.1 - 0.0057 16.0 0.2 0.0086 15.4 0.2 1.2 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) DUF148 PF02520.12 ETO30713.1 - 0.011 15.5 0.2 0.016 14.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF148 Syntaxin PF00804.20 ETO30713.1 - 0.083 13.0 1.3 0.12 12.5 0.3 1.7 2 0 0 2 2 2 0 Syntaxin DUF4473 PF14747.1 ETO30713.1 - 0.13 12.4 1.0 0.27 11.4 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) Myosin_TH1 PF06017.8 ETO30714.1 - 5.1e-14 52.0 3.0 9.7e-14 51.1 2.1 1.5 1 1 0 1 1 1 1 Myosin tail hSac2 PF12456.3 ETO30714.1 - 9.7e-05 21.7 0.0 0.00015 21.1 0.0 1.5 1 0 0 1 1 1 1 Inositol phosphatase PH_3 PF14593.1 ETO30714.1 - 0.014 15.2 1.0 0.014 15.2 0.7 1.8 1 1 1 2 2 2 0 PH domain PH PF00169.24 ETO30714.1 - 0.041 14.0 1.4 0.1 12.8 0.8 1.9 1 1 0 1 1 1 0 PH domain Ion_trans PF00520.26 ETO30716.1 - 1.3e-28 99.6 43.9 5.3e-17 61.7 10.8 2.9 2 1 0 2 2 2 2 Ion transport protein cNMP_binding PF00027.24 ETO30716.1 - 0.00068 19.3 0.0 0.0019 18.0 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain GRP PF07172.6 ETO30716.1 - 0.086 13.3 0.4 0.086 13.3 0.3 3.0 3 0 0 3 3 3 0 Glycine rich protein family Tim54 PF11711.3 ETO30716.1 - 0.28 9.7 2.0 0.55 8.7 1.4 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Prog_receptor PF02161.10 ETO30716.1 - 1.7 7.4 4.1 2.7 6.7 2.9 1.3 1 0 0 1 1 1 0 Progesterone receptor TEX19 PF15553.1 ETO30716.1 - 8.4 6.2 8.0 36 4.1 4.3 2.3 2 0 0 2 2 2 0 Testis-expressed protein 19 Atg8 PF02991.11 ETO30718.1 - 6.2e-35 119.3 0.3 7.2e-35 119.0 0.2 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 ETO30718.1 - 0.015 15.4 0.1 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 DSPc PF00782.15 ETO30719.1 - 3.7e-08 33.0 0.0 8e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Ribosomal_L14e PF01929.12 ETO30720.1 - 1.5e-14 54.1 1.8 7.1e-14 51.9 0.1 2.5 2 0 0 2 2 2 1 Ribosomal protein L14 LRR_6 PF13516.1 ETO30721.1 - 1.5e-08 33.8 24.4 0.0042 17.0 0.1 8.9 9 1 1 10 10 10 4 Leucine Rich repeat LRR_4 PF12799.2 ETO30721.1 - 1.1e-05 24.8 18.2 0.21 11.2 0.0 6.5 4 3 2 6 6 6 4 Leucine Rich repeats (2 copies) Methyltrn_RNA_2 PF04013.7 ETO30721.1 - 0.041 13.4 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative SAM-dependent RNA methyltransferase LRR_1 PF00560.28 ETO30721.1 - 0.92 9.7 27.3 21 5.6 1.1 9.1 9 2 0 9 9 9 0 Leucine Rich Repeat Dus PF01207.12 ETO30722.1 - 2e-23 82.7 0.4 3.2e-23 82.0 0.0 1.6 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 ETO30722.1 - 0.00086 18.6 0.0 0.0016 17.7 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.12 ETO30723.1 - 8.3e-35 120.0 0.0 1.1e-34 119.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) GHMP_kinases_N PF00288.21 ETO30724.1 - 5.3e-12 45.6 0.8 1.5e-11 44.1 0.6 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 ETO30724.1 - 0.00011 22.3 0.0 0.00021 21.4 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal Myosin_TH1 PF06017.8 ETO30726.1 - 3.8e-10 39.4 1.4 3.8e-10 39.4 1.0 1.7 1 1 1 2 2 2 1 Myosin tail hSac2 PF12456.3 ETO30726.1 - 2.9e-05 23.4 0.1 5.8e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Inositol phosphatase ParG PF09274.5 ETO30726.1 - 0.038 13.9 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 ParG SF-assemblin PF06705.6 ETO30726.1 - 0.041 13.0 0.3 0.05 12.7 0.2 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin TPR_12 PF13424.1 ETO30727.1 - 3.5e-16 58.8 0.2 3e-08 33.4 0.0 2.2 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO30727.1 - 1.4e-12 47.0 2.6 1.9e-12 46.6 1.2 1.6 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 ETO30727.1 - 1.6e-12 46.4 9.1 7.5e-09 34.8 0.8 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO30727.1 - 1.2e-10 40.3 8.3 0.00023 20.7 0.9 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO30727.1 - 5.8e-10 38.3 4.1 7.7e-06 25.4 0.2 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO30727.1 - 3.8e-08 32.5 0.2 0.014 15.1 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO30727.1 - 3.4e-06 26.7 0.0 0.0038 17.0 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO30727.1 - 0.001 19.0 4.8 0.58 10.5 1.0 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat SNAP PF14938.1 ETO30727.1 - 0.027 13.6 0.2 0.039 13.0 0.1 1.2 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_6 PF13174.1 ETO30727.1 - 0.15 12.6 0.0 73 4.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 ETO30727.1 - 0.39 10.6 2.0 0.9 9.4 0.1 2.3 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPD PF14811.1 ETO30728.1 - 2.3e-07 30.4 1.1 4e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function TPD sequence-motif PP-binding PF00550.20 ETO30730.1 - 8.6e-06 25.9 0.1 0.12 12.6 0.0 2.4 2 0 0 2 2 2 2 Phosphopantetheine attachment site PP-binding_2 PF14573.1 ETO30730.1 - 0.068 13.2 0.4 0.55 10.2 0.1 2.2 2 0 0 2 2 2 0 Acyl-carrier Rotamase PF00639.16 ETO30731.1 - 5.1e-19 68.8 0.1 5.1e-19 68.8 0.1 2.3 1 1 1 2 2 2 1 PPIC-type PPIASE domain FHA PF00498.21 ETO30731.1 - 5.9e-13 48.7 0.0 1.9e-12 47.1 0.0 1.9 1 0 0 1 1 1 1 FHA domain Rotamase_3 PF13616.1 ETO30731.1 - 1.2e-12 48.1 0.3 3.3e-12 46.6 0.1 1.9 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 ETO30731.1 - 4.2e-05 24.1 0.4 0.00012 22.7 0.0 1.9 1 1 2 3 3 3 1 PPIC-type PPIASE domain Prominin PF05478.6 ETO30731.1 - 0.041 11.4 1.5 0.077 10.5 0.0 1.8 2 0 0 2 2 2 0 Prominin DUF1381 PF07129.6 ETO30731.1 - 2.6 7.5 5.2 13 5.2 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1381) PHD PF00628.24 ETO30732.1 - 2.9e-08 33.2 6.9 6.6e-08 32.1 4.8 1.6 1 0 0 1 1 1 1 PHD-finger MIP-T3 PF10243.4 ETO30732.1 - 0.017 13.6 42.9 0.019 13.4 29.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 zf-HC5HC2H PF13771.1 ETO30732.1 - 0.019 15.1 4.2 0.019 15.1 2.9 2.0 2 0 0 2 2 2 0 PHD-like zinc-binding domain Prok-RING_1 PF14446.1 ETO30732.1 - 0.029 14.1 5.3 0.029 14.1 3.7 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 COX2_TM PF02790.10 ETO30732.1 - 0.23 11.4 3.2 0.34 10.9 0.9 2.0 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain Daxx PF03344.10 ETO30732.1 - 2.8 6.3 27.1 3.2 6.1 18.8 1.0 1 0 0 1 1 1 0 Daxx Family zf-RING_2 PF13639.1 ETO30732.1 - 3 7.7 8.6 5.4 6.9 6.0 1.4 1 0 0 1 1 1 0 Ring finger domain DUF1771 PF08590.5 ETO30734.1 - 5.4e-18 64.7 2.9 9.5e-18 63.9 2.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 ETO30734.1 - 8.7e-05 22.6 0.1 0.00049 20.2 0.0 2.3 2 0 0 2 2 2 1 Smr domain zf-CCCH PF00642.19 ETO30734.1 - 0.014 15.0 4.2 0.25 11.0 0.1 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF2847 PF11009.3 ETO30734.1 - 0.035 13.6 0.6 0.035 13.6 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2847) PhoU PF01895.14 ETO30734.1 - 0.065 13.6 0.3 0.19 12.2 0.2 1.8 1 0 0 1 1 1 0 PhoU domain MGC-24 PF05283.6 ETO30734.1 - 4.6 7.0 13.3 0.42 10.3 5.1 1.9 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) PAM2 PF07145.10 ETO30735.1 - 0.00016 20.9 0.2 0.00046 19.4 0.1 1.7 1 0 0 1 1 1 1 Ataxin-2 C-terminal region zf-CCCH PF00642.19 ETO30735.1 - 0.0024 17.5 0.7 0.025 14.2 0.3 2.4 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CUE PF02845.11 ETO30735.1 - 0.033 13.6 0.0 0.076 12.5 0.0 1.7 1 0 0 1 1 1 0 CUE domain zf-CCCH_2 PF14608.1 ETO30735.1 - 0.38 10.8 9.0 0.5 10.4 1.5 3.3 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type zf-C3H1 PF10650.4 ETO30735.1 - 0.39 10.2 5.1 0.11 11.9 1.1 2.0 2 0 0 2 2 2 0 Putative zinc-finger domain ASFV_360 PF01671.11 ETO30736.1 - 0.02 14.2 0.3 0.032 13.6 0.2 1.3 1 0 0 1 1 1 0 African swine fever virus multigene family 360 protein DUF3791 PF12668.2 ETO30736.1 - 0.02 14.4 0.4 0.047 13.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) DUF3439 PF11921.3 ETO30736.1 - 0.56 9.9 10.2 1.4 8.7 7.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TMF_DNA_bd PF12329.3 ETO30737.1 - 0.014 15.1 1.4 0.014 15.1 1.0 4.1 1 1 3 4 4 3 0 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.16 ETO30737.1 - 0.022 14.7 4.2 0.022 14.7 2.9 4.4 3 2 1 4 4 4 0 bZIP transcription factor DUF730 PF05325.6 ETO30737.1 - 0.032 14.0 0.6 0.032 14.0 0.4 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF730) Nup54 PF13874.1 ETO30737.1 - 0.034 13.7 19.5 0.11 12.1 6.4 2.4 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DUF3584 PF12128.3 ETO30737.1 - 0.18 9.0 25.9 0.23 8.7 18.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4201 PF13870.1 ETO30737.1 - 0.2 11.0 21.8 0.31 10.4 3.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) APG6 PF04111.7 ETO30737.1 - 0.24 10.4 29.6 0.3 10.0 5.1 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 ADIP PF11559.3 ETO30737.1 - 0.44 10.4 26.9 0.082 12.8 3.4 2.9 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding HALZ PF02183.13 ETO30737.1 - 0.46 10.2 18.8 4 7.2 2.5 4.4 3 1 1 4 4 4 0 Homeobox associated leucine zipper DUF869 PF05911.6 ETO30737.1 - 0.73 7.9 28.2 2.5 6.2 19.6 1.7 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) MCC-bdg_PDZ PF10506.4 ETO30737.1 - 0.82 9.5 11.3 2.1 8.2 3.2 2.6 2 1 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome GAS PF13851.1 ETO30737.1 - 1.1 8.3 32.3 1.5 7.9 6.5 3.0 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.4 ETO30737.1 - 1.8 8.5 25.7 0.54 10.2 7.9 2.5 1 1 0 2 2 2 0 JNK_SAPK-associated protein-1 CENP-F_leu_zip PF10473.4 ETO30737.1 - 1.9 8.3 37.4 7.5 6.4 11.5 2.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF812 PF05667.6 ETO30737.1 - 2.1 6.7 29.2 0.66 8.4 7.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF3450 PF11932.3 ETO30737.1 - 3.9 6.6 22.4 2.4 7.3 3.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4446 PF14584.1 ETO30737.1 - 4.2 7.1 15.7 0.27 11.0 1.7 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) DUF972 PF06156.8 ETO30737.1 - 5.6 7.3 30.2 6.1 7.2 8.3 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Ax_dynein_light PF10211.4 ETO30737.1 - 9 6.0 27.7 2.1 8.1 6.9 2.7 1 1 0 2 2 2 0 Axonemal dynein light chain TPP1 PF10341.4 ETO30738.1 - 0.026 14.5 0.2 0.057 13.4 0.1 1.5 1 1 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD Bromo_coat PF01318.13 ETO30738.1 - 0.078 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Bromovirus coat protein zf-TRAF PF02176.13 ETO30741.1 - 0.00019 21.7 5.4 0.00036 20.8 2.2 2.7 2 0 0 2 2 2 1 TRAF-type zinc finger Secretin_N_2 PF07655.8 ETO30741.1 - 0.025 14.9 11.3 0.025 14.9 7.8 2.6 2 1 0 2 2 2 0 Secretin N-terminal domain Peptidase_S46 PF10459.4 ETO30741.1 - 0.061 11.7 8.7 0.094 11.1 6.0 1.2 1 0 0 1 1 1 0 Peptidase S46 DUF4047 PF13256.1 ETO30741.1 - 4.6 7.2 10.3 9.9 6.1 7.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) Kelch_6 PF13964.1 ETO30742.1 - 7.3e-06 25.9 4.5 0.27 11.4 0.0 4.9 4 1 1 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO30742.1 - 0.00074 19.0 2.1 0.12 11.9 0.0 3.8 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO30742.1 - 0.00087 18.9 0.4 0.52 10.1 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 ETO30742.1 - 0.0011 18.9 0.9 4.7 7.2 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO30742.1 - 0.083 13.0 0.7 17 5.7 0.0 3.8 5 0 0 5 5 5 0 Galactose oxidase, central domain Alpha_L_fucos PF01120.12 ETO30743.1 - 8.1e-21 74.2 0.4 1.7e-20 73.2 0.2 1.6 1 1 0 1 1 1 1 Alpha-L-fucosidase UN_NPL4 PF11543.3 ETO30744.1 - 0.00011 22.4 0.0 0.00028 21.1 0.0 1.7 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 DSPc PF00782.15 ETO30745.1 - 2e-06 27.3 0.0 6.2e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Hepcidin PF06446.7 ETO30747.1 - 2.9 8.3 5.1 9.8 6.6 0.3 3.0 2 1 1 3 3 3 0 Hepcidin Ion_trans PF00520.26 ETO30749.1 - 6.4e-17 61.4 24.9 6.4e-17 61.4 17.3 3.6 4 1 1 5 5 5 2 Ion transport protein Neur_chan_memb PF02932.11 ETO30749.1 - 0.011 15.5 0.2 0.011 15.5 0.1 2.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region EF-hand_6 PF13405.1 ETO30749.1 - 0.034 14.0 1.1 6.1 7.0 0.2 3.0 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.27 ETO30749.1 - 0.22 10.9 2.2 1.5 8.2 0.5 2.6 2 0 0 2 2 2 0 EF hand WD40 PF00400.27 ETO30752.1 - 1.2e-51 170.8 10.9 2.8e-13 49.1 0.3 6.1 5 1 1 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO30752.1 - 1.2e-06 26.9 2.9 0.13 10.3 0.1 3.0 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO30752.1 - 9.6e-05 21.3 5.9 0.042 12.6 0.3 3.1 1 1 1 3 3 3 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO30752.1 - 0.01 14.1 0.4 0.13 10.5 0.1 2.1 1 1 0 2 2 2 0 Cytochrome D1 heme domain SGL PF08450.7 ETO30752.1 - 0.084 12.2 0.1 1.9 7.8 0.0 2.2 1 1 1 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region IQ-like PF15157.1 ETO30752.1 - 0.093 12.9 0.1 15 5.8 0.0 2.3 2 0 0 2 2 2 0 IQ-like Ribosomal_S26e PF01283.14 ETO30752.1 - 0.12 12.5 0.9 0.24 11.6 0.2 1.7 2 0 0 2 2 2 0 Ribosomal protein S26e Baculo_LEF-11 PF06385.7 ETO30752.1 - 0.18 11.9 1.3 0.34 11.0 0.1 2.0 2 1 0 2 2 2 0 Baculovirus LEF-11 protein Evr1_Alr PF04777.8 ETO30753.1 - 2.1e-20 72.4 0.6 2.7e-20 72.0 0.4 1.2 1 0 0 1 1 1 1 Erv1 / Alr family Zn_ribbon_recom PF13408.1 ETO30753.1 - 0.042 14.1 0.1 0.079 13.2 0.1 1.6 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain Lung_7-TM_R PF06814.8 ETO30755.1 - 3.5e-46 157.5 16.1 2.6e-45 154.6 11.1 1.9 1 1 0 1 1 1 1 Lung seven transmembrane receptor ETRAMP PF09716.5 ETO30755.1 - 0.29 11.1 0.0 0.29 11.1 0.0 2.6 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) G-alpha PF00503.15 ETO30756.1 - 6.8e-24 84.2 1.7 1.4e-23 83.2 1.2 1.6 1 1 0 1 1 1 1 G-protein alpha subunit G-alpha PF00503.15 ETO30757.1 - 6.9e-44 150.0 1.9 7.8e-44 149.9 1.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO30757.1 - 2.2e-10 40.0 0.1 3.6e-10 39.3 0.1 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 ETO30757.1 - 0.038 14.4 0.0 0.051 14.0 0.0 1.4 1 1 0 1 1 1 0 Miro-like protein FCP1_C PF09309.5 ETO30758.1 - 0.0042 16.4 3.9 0.0042 16.4 2.7 3.8 2 1 2 4 4 4 1 FCP1, C-terminal DUF2422 PF10337.4 ETO30758.1 - 7.2 5.2 8.4 4.5 5.9 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) RPEL PF02755.10 ETO30759.1 - 6.7e-10 37.9 69.0 0.17 11.2 0.3 19.7 22 1 1 23 23 23 12 RPEL repeat Pyridoxal_deC PF00282.14 ETO30760.1 - 5.6e-61 206.0 0.0 2.5e-50 170.9 0.0 2.3 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.16 ETO30760.1 - 5.2e-06 25.6 0.0 1.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 ETO30760.1 - 3.5e-05 22.7 0.0 0.00011 21.0 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 ETO30760.1 - 0.00031 19.9 0.0 0.00047 19.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase SLA_LP_auto_ag PF05889.8 ETO30760.1 - 0.00044 18.8 0.0 0.00084 17.9 0.0 1.4 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) FlaC_arch PF05377.6 ETO30760.1 - 0.0014 18.4 0.3 0.0033 17.2 0.2 1.6 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) MFS_1 PF07690.11 ETO30762.1 - 0.95 8.1 8.9 0.11 11.1 1.0 2.0 1 1 1 2 2 2 0 Major Facilitator Superfamily NTP_transf_2 PF01909.18 ETO30763.1 - 5e-10 39.5 0.0 1.3e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 ETO30763.1 - 3.5e-05 23.6 2.3 0.00059 19.7 1.4 3.1 2 1 0 2 2 2 1 Cid1 family poly A polymerase zf-CCCH PF00642.19 ETO30763.1 - 0.0029 17.2 9.4 0.23 11.1 1.0 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Zip PF02535.17 ETO30763.1 - 0.0035 16.4 1.9 0.0035 16.4 1.3 2.1 2 1 0 2 2 2 1 ZIP Zinc transporter GATase PF00117.23 ETO30764.1 - 3.7e-07 29.7 0.0 5.5e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 ETO30764.1 - 3.3e-06 26.6 0.0 7.9e-06 25.4 0.0 1.6 1 1 0 1 1 1 1 Peptidase C26 GATase_5 PF13507.1 ETO30764.1 - 0.00059 18.8 0.0 0.26 10.1 0.0 2.1 2 0 0 2 2 2 2 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 ETO30764.1 - 0.015 14.9 0.0 0.058 13.0 0.0 1.8 2 0 0 2 2 2 0 SNO glutamine amidotransferase family Molybdop_Fe4S4 PF04879.11 ETO30764.1 - 0.045 13.5 0.0 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin oxidoreductase Fe4S4 domain PPR PF01535.15 ETO30765.1 - 9.9e-10 37.7 4.6 0.13 12.2 0.0 4.6 4 0 0 4 4 4 4 PPR repeat PPR_2 PF13041.1 ETO30765.1 - 5.6e-08 32.6 2.2 0.023 14.6 0.1 3.6 2 1 1 3 3 3 3 PPR repeat family PPR_3 PF13812.1 ETO30765.1 - 4.8e-05 23.3 0.0 1.2 9.5 0.0 4.6 5 0 0 5 5 5 1 Pentatricopeptide repeat domain DUF3636 PF12331.3 ETO30765.1 - 0.016 14.7 0.1 0.031 13.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3636) Peptidase_M16 PF00675.15 ETO30766.1 - 1.1e-41 142.0 0.0 1.6e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) WD40 PF00400.27 ETO30767.1 - 1.7e-34 116.4 13.1 1.6e-09 37.2 0.1 7.5 8 0 0 8 8 8 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO30767.1 - 9.1e-08 31.2 5.1 1.1e-06 27.6 0.9 3.5 1 1 1 2 2 2 1 Nup133 N terminal like Nup160 PF11715.3 ETO30767.1 - 1.1e-05 23.7 6.3 0.15 10.1 0.0 3.6 2 2 1 4 4 4 3 Nucleoporin Nup120/160 Hira PF07569.6 ETO30767.1 - 0.0031 16.7 0.5 8.6 5.5 0.0 3.9 3 1 1 4 4 4 2 TUP1-like enhancer of split DUF3312 PF11768.3 ETO30767.1 - 0.023 12.9 0.0 0.038 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Dfp1_Him1_M PF08630.5 ETO30767.1 - 0.029 14.1 0.6 0.14 11.9 0.1 2.2 2 0 0 2 2 2 0 Dfp1/Him1, central region RicinB_lectin_2 PF14200.1 ETO30767.1 - 0.088 13.1 1.9 6.7 7.1 0.0 2.9 2 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like U-box PF04564.10 ETO30768.1 - 8.8e-16 57.6 0.0 1.3e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 U-box domain SAM_1 PF00536.25 ETO30768.1 - 9.8e-07 28.8 0.3 8.7e-06 25.8 0.1 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO30768.1 - 0.00045 20.0 0.4 0.00082 19.1 0.1 1.6 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) zf-Nse PF11789.3 ETO30768.1 - 0.0066 15.9 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit RRM_1 PF00076.17 ETO30769.1 - 1.5e-24 85.3 0.1 1.2e-14 53.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO30769.1 - 6.4e-14 51.6 0.0 4e-09 36.3 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO30769.1 - 3.1e-13 49.3 0.0 4.5e-07 29.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L29e PF01779.12 ETO30770.1 - 4.6e-14 51.9 10.2 6.8e-13 48.2 7.1 2.5 1 1 0 1 1 1 1 Ribosomal L29e protein family DUF382 PF04037.8 ETO30770.1 - 0.0044 16.8 1.5 0.0052 16.6 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF382) DUF3959 PF13105.1 ETO30770.1 - 0.92 8.7 4.2 1.1 8.5 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) DUF4612 PF15389.1 ETO30771.1 - 0.032 14.8 1.2 0.032 14.8 0.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4612) Peptidase_S49_N PF08496.5 ETO30771.1 - 5.7 6.7 7.8 28 4.4 0.1 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Peptidase_M16_C PF05193.16 ETO30772.1 - 1.6e-13 50.7 0.0 2.3e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16 inactive domain DUF1597 PF07642.6 ETO30772.1 - 0.025 13.5 0.0 0.037 13.0 0.0 1.3 1 0 0 1 1 1 0 Outer membrane protein family (DUF1597) Peptidase_M16_C PF05193.16 ETO30773.1 - 3.2e-12 46.5 0.1 4.7e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 ETO30773.1 - 0.026 14.2 0.0 0.076 12.7 0.0 1.7 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) DUF386 PF04074.7 ETO30773.1 - 0.064 12.7 0.4 0.18 11.3 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF386) Glyco_transf_20 PF00982.16 ETO30774.1 - 6e-99 331.6 0.1 8.2e-99 331.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 ETO30774.1 - 2.5e-29 101.8 0.0 5.9e-29 100.6 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase CBS PF00571.23 ETO30775.1 - 1.3e-16 60.0 0.1 4.1e-13 48.8 0.1 2.5 2 1 0 2 2 2 2 CBS domain DUF2607 PF10795.4 ETO30776.1 - 0.043 13.6 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2607) B56 PF01603.15 ETO30778.1 - 1.7e-93 313.4 7.0 2.2e-93 313.1 4.8 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) TSKS PF15358.1 ETO30778.1 - 0.1 10.7 0.0 0.51 8.4 0.0 1.8 2 0 0 2 2 2 0 Testis-specific serine kinase substrate Rav1p_C PF12234.3 ETO30780.1 - 4.2e-27 94.6 1.3 2.6e-20 72.1 0.0 2.4 2 0 0 2 2 2 2 RAVE protein 1 C terminal WD40 PF00400.27 ETO30780.1 - 0.0013 18.5 0.6 1.5 8.8 0.1 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat Menin PF05053.8 ETO30780.1 - 7.5 4.5 28.3 0.49 8.5 2.6 3.2 3 0 0 3 3 3 0 Menin Vfa1 PF08432.5 ETO30781.1 - 2.1 8.3 28.7 0.24 11.4 11.7 3.6 4 0 0 4 4 4 0 AAA-ATPase Vps4-associated protein 1 Guanylate_cyc PF00211.15 ETO30782.1 - 1.6e-05 24.3 0.0 3.1e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Choline_transpo PF04515.7 ETO30783.1 - 3e-71 239.8 19.2 3e-71 239.8 13.3 2.6 2 1 1 3 3 3 1 Plasma-membrane choline transporter WD40 PF00400.27 ETO30784.1 - 1.1e-58 193.0 18.6 6.3e-11 41.7 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO30784.1 - 7.5e-09 34.2 1.2 0.0097 14.0 0.0 3.7 3 1 1 4 4 4 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO30784.1 - 0.012 15.4 0.5 4.5 7.0 0.0 4.3 4 1 0 5 5 5 0 Ciliary BBSome complex subunit 2, middle region Peptidase_C14 PF00656.17 ETO30785.1 - 1.3e-08 34.8 0.4 1.8e-08 34.3 0.3 1.2 1 0 0 1 1 1 1 Caspase domain Phage_int_SAM_4 PF13495.1 ETO30785.1 - 0.014 15.7 0.0 0.058 13.7 0.0 1.9 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Kelch_5 PF13854.1 ETO30786.1 - 4.4e-05 23.3 0.2 1.9 8.5 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO30786.1 - 0.00016 21.7 3.6 0.15 12.2 0.0 3.5 3 1 1 4 4 4 2 Kelch motif IL3 PF02059.10 ETO30786.1 - 0.00036 20.5 0.1 0.00036 20.5 0.1 2.9 3 1 0 3 3 3 1 Interleukin-3 Kelch_1 PF01344.20 ETO30786.1 - 0.00063 19.2 9.5 0.01 15.3 0.1 4.3 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO30786.1 - 0.0019 17.8 5.7 1.3 8.8 0.0 4.4 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO30786.1 - 0.013 15.2 0.2 2.4 7.9 0.0 3.1 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO30786.1 - 0.093 12.9 0.1 1.7 8.9 0.0 2.9 2 0 0 2 2 2 0 Galactose oxidase, central domain PBP1_TM PF14812.1 ETO30788.1 - 2 8.7 8.6 0.8 10.0 3.6 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mucin PF01456.12 ETO30788.1 - 2.3 7.9 22.2 4.5 7.0 15.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein FAM176 PF14851.1 ETO30788.1 - 4.2 7.0 5.5 0.62 9.7 0.9 1.8 2 0 0 2 2 2 0 FAM176 family CENP-B_dimeris PF09026.5 ETO30788.1 - 5.8 7.2 14.3 0.64 10.2 4.8 2.4 3 0 0 3 3 3 0 Centromere protein B dimerisation domain PT PF04886.7 ETO30789.1 - 0.0022 17.2 17.2 0.0022 17.2 11.9 2.7 2 0 0 2 2 2 2 PT repeat Med13_C PF06333.7 ETO30789.1 - 0.069 11.6 1.7 0.17 10.4 0.0 1.9 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal Ion_trans PF00520.26 ETO30790.1 - 6.4e-09 35.3 22.4 6.4e-09 35.3 15.5 2.8 2 1 0 2 2 2 1 Ion transport protein VPS9 PF02204.13 ETO30791.1 - 0.0025 17.8 0.1 0.0051 16.8 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF523 PF04463.7 ETO30791.1 - 0.016 14.9 1.1 0.033 13.9 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF523) DUF2420 PF10336.4 ETO30791.1 - 0.024 14.2 0.6 0.075 12.6 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2420) PRD PF00874.15 ETO30791.1 - 1.6 8.9 5.5 27 4.9 0.0 3.8 2 1 2 4 4 4 0 PRD domain VWA_3 PF13768.1 ETO30792.1 - 0.0054 16.4 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Vma12 PF11712.3 ETO30793.1 - 1.2e-10 41.2 0.0 1.8e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Syndecan PF01034.15 ETO30793.1 - 0.059 13.0 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Syndecan domain TGT PF01702.13 ETO30794.1 - 4.4e-13 49.0 0.2 6.7e-13 48.4 0.2 1.3 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase TGT PF01702.13 ETO30795.1 - 4.7e-59 199.5 0.1 5.6e-59 199.3 0.1 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DUF3596 PF12167.3 ETO30795.1 - 0.091 12.3 0.0 0.18 11.3 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3596) Josephin PF02099.12 ETO30796.1 - 1.8e-10 40.6 0.4 2.6e-10 40.1 0.3 1.2 1 0 0 1 1 1 1 Josephin Sulfotransfer_2 PF03567.9 ETO30798.1 - 1.6e-08 34.5 6.3 9e-08 32.1 1.6 2.4 2 1 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.22 ETO30798.1 - 1.7e-05 24.1 5.8 0.00024 20.4 1.6 3.1 2 2 1 3 3 3 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 ETO30798.1 - 0.0064 17.4 0.0 0.013 16.4 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase family IL5 PF02025.10 ETO30798.1 - 0.48 10.4 4.5 0.2 11.6 0.4 2.3 2 1 0 2 2 2 0 Interleukin 5 POX PF07526.6 ETO30799.1 - 5.1 7.3 18.4 6.6 6.9 0.1 3.1 3 0 0 3 3 3 0 Associated with HOX EF-hand_7 PF13499.1 ETO30800.1 - 0.00083 19.4 0.0 0.078 13.1 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair UBN2 PF14223.1 ETO30800.1 - 0.001 18.8 0.5 0.83 9.4 1.1 2.7 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type EF-hand_1 PF00036.27 ETO30800.1 - 0.0037 16.4 0.0 0.14 11.5 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 ETO30800.1 - 0.0092 15.7 0.2 1.5 8.8 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain TBP PF00352.16 ETO30802.1 - 9.8e-20 69.7 0.4 7.6e-12 44.4 0.6 2.4 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) G-alpha PF00503.15 ETO30803.1 - 2.1e-24 85.9 0.4 2.8e-24 85.5 0.3 1.1 1 0 0 1 1 1 1 G-protein alpha subunit ABC_tran PF00005.22 ETO30803.1 - 0.0013 19.0 0.3 0.0019 18.5 0.2 1.3 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 ETO30803.1 - 0.048 13.1 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 ETO30803.1 - 0.055 13.7 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain CWC25 PF12542.3 ETO30804.1 - 9 6.8 14.4 16 6.0 0.1 3.1 1 1 1 2 2 2 0 Pre-mRNA splicing factor Bax1-I PF01027.15 ETO30805.1 - 3.7e-26 92.0 6.1 5.1e-26 91.5 4.3 1.3 1 1 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 FUSC_2 PF13515.1 ETO30805.1 - 5.4 6.9 10.5 9.1 6.2 7.3 1.6 1 1 0 1 1 1 0 Fusaric acid resistance protein-like Syntaphilin PF15290.1 ETO30806.1 - 0.6 9.5 3.2 1 8.7 2.2 1.4 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp CAF-1_p150 PF11600.3 ETO30806.1 - 1.9 7.8 7.3 0.59 9.4 3.4 1.4 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SR-25 PF10500.4 ETO30806.1 - 2 7.8 18.1 0.074 12.5 7.0 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF912 PF06024.7 ETO30807.1 - 0.22 11.6 4.5 2.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Protamine_P2 PF00841.14 ETO30808.1 - 0.089 13.3 0.2 0.18 12.3 0.1 1.5 1 0 0 1 1 1 0 Sperm histone P2 DUF1980 PF09323.5 ETO30808.1 - 0.3 10.8 3.4 17 5.1 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1980) Ax_dynein_light PF10211.4 ETO30810.1 - 0.0025 17.6 2.4 0.0039 17.0 1.7 1.2 1 0 0 1 1 1 1 Axonemal dynein light chain GNT-I PF03071.10 ETO30810.1 - 0.0054 15.3 0.1 0.0074 14.8 0.1 1.2 1 0 0 1 1 1 1 GNT-I family Glycos_transf_2 PF00535.21 ETO30810.1 - 0.012 15.3 0.1 0.031 13.9 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF3972 PF13118.1 ETO30810.1 - 0.025 14.6 0.7 0.043 13.8 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) CCDC92 PF14916.1 ETO30810.1 - 0.028 14.0 0.3 0.051 13.1 0.2 1.4 1 0 0 1 1 1 0 Coiled-coil domain of unknown function DUF904 PF06005.7 ETO30810.1 - 0.032 14.5 1.8 0.09 13.0 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF3192 PF11399.3 ETO30810.1 - 0.06 13.2 2.1 0.28 11.1 0.0 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3192) HALZ PF02183.13 ETO30810.1 - 0.24 11.1 6.1 0.1 12.3 1.7 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper DivIC PF04977.10 ETO30810.1 - 0.25 10.8 6.1 0.15 11.5 2.0 2.2 2 0 0 2 2 2 0 Septum formation initiator GNT-I PF03071.10 ETO30811.1 - 4.8e-94 315.3 7.5 6.3e-94 314.9 5.2 1.0 1 0 0 1 1 1 1 GNT-I family Glyco_transf_25 PF01755.12 ETO30811.1 - 0.03 13.9 0.6 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase family 25 (LPS biosynthesis protein) DUF1774 PF08611.5 ETO30812.1 - 2.6 8.2 8.3 4.3 7.5 5.7 1.3 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1774) Ribosomal_L15e PF00827.12 ETO30813.1 - 1.3e-63 214.0 3.4 2.4e-63 213.1 2.3 1.4 1 0 0 1 1 1 1 Ribosomal L15 LmjF365940-deam PF14421.1 ETO30815.1 - 3e-39 134.4 0.0 4.1e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 A distinct subfamily of CDD/CDA-like deaminases dCMP_cyt_deam_1 PF00383.17 ETO30815.1 - 0.0014 18.2 0.1 0.042 13.5 0.0 2.3 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region RCC1 PF00415.13 ETO30816.1 - 1.4e-06 28.3 4.0 0.00028 21.0 0.0 4.4 4 1 0 4 4 4 1 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO30816.1 - 1.7e-06 27.4 1.6 0.062 12.9 0.0 3.4 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Pollen_Ole_e_I PF01190.12 ETO30818.1 - 0.062 13.1 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Pollen proteins Ole e I like DUF2312 PF10073.4 ETO30818.1 - 0.081 12.2 3.1 0.24 10.7 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) RseA_C PF03873.8 ETO30818.1 - 7.4 6.5 6.5 7 6.6 0.1 2.8 3 0 0 3 3 3 0 Anti sigma-E protein RseA, C-terminal domain NT5C PF06941.7 ETO30819.1 - 3.8e-06 26.5 1.5 5.6e-06 25.9 0.1 2.0 2 1 0 2 2 2 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) HAD_2 PF13419.1 ETO30819.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.5 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase zf-UBP PF02148.14 ETO30821.1 - 2.2e-13 50.1 0.3 9.4e-13 48.0 0.0 2.2 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein UCH PF00443.24 ETO30821.1 - 1.1e-10 41.0 0.0 2e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO30821.1 - 8.4e-05 22.1 0.0 0.00015 21.2 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF966 PF06136.8 ETO30821.1 - 0.05 13.0 0.1 0.069 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) UCH PF00443.24 ETO30822.1 - 1.1e-22 80.4 0.0 1.4e-22 80.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 ETO30822.1 - 9.9e-11 41.1 2.2 8.9e-05 22.2 0.0 2.4 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.1 ETO30822.1 - 5.2e-10 39.2 0.1 5e-09 36.0 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA_2 PF08587.6 ETO30822.1 - 0.0012 18.9 0.7 0.01 16.0 0.0 2.6 3 0 0 3 3 3 1 Ubiquitin associated domain (UBA) DUF3464 PF11947.3 ETO30822.1 - 0.1 12.0 0.3 0.2 11.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) CENP-B_dimeris PF09026.5 ETO30822.1 - 0.12 12.6 2.6 0.33 11.2 1.8 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2956 PF11169.3 ETO30822.1 - 0.25 11.3 6.4 0.59 10.1 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Atrophin-1 PF03154.10 ETO30822.1 - 0.27 9.3 8.3 0.43 8.6 5.8 1.2 1 0 0 1 1 1 0 Atrophin-1 family DUF3987 PF13148.1 ETO30822.1 - 1.1 7.6 7.2 2.1 6.8 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Vfa1 PF08432.5 ETO30822.1 - 1.5 8.7 14.3 0.85 9.6 7.9 1.9 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Peptidase_S49_N PF08496.5 ETO30822.1 - 2 8.2 7.2 1.2 8.9 3.3 1.8 2 0 0 2 2 2 0 Peptidase family S49 N-terminal SHR3_chaperone PF08229.6 ETO30822.1 - 3.6 6.4 4.7 7.2 5.5 3.2 1.4 1 0 0 1 1 1 0 ER membrane protein SH3 CT47 PF15623.1 ETO30822.1 - 8.7 5.9 14.3 2.3 7.8 7.8 1.6 2 0 0 2 2 2 0 Cancer/testis gene family 47 FIBP PF05427.6 ETO30823.1 - 0.0034 16.6 2.1 0.0043 16.3 1.5 1.2 1 0 0 1 1 1 1 Acidic fibroblast growth factor binding (FIBP) SdiA-regulated PF06977.6 ETO30824.1 - 0.04 12.8 0.1 0.045 12.6 0.1 1.1 1 0 0 1 1 1 0 SdiA-regulated MmgE_PrpD PF03972.9 ETO30825.1 - 0.00085 17.6 0.0 0.0011 17.2 0.0 1.1 1 0 0 1 1 1 1 MmgE/PrpD family ETRAMP PF09716.5 ETO30826.1 - 0.017 15.0 0.2 0.57 10.1 0.0 2.3 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF1510 PF07423.6 ETO30826.1 - 0.31 10.3 23.4 0.51 9.6 10.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Hepcidin PF06446.7 ETO30826.1 - 0.63 10.4 3.0 1.9 8.9 1.3 2.4 2 0 0 2 2 2 0 Hepcidin TRAP_alpha PF03896.11 ETO30826.1 - 7 5.5 11.3 67 2.3 0.0 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Pox_Ag35 PF03286.9 ETO30826.1 - 7.8 5.9 22.3 2.7 7.4 0.6 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Dynein_light PF01221.13 ETO30827.1 - 3.2e-35 119.9 8.5 2e-32 111.0 1.9 2.4 1 1 1 2 2 2 2 Dynein light chain type 1 Pkinase PF00069.20 ETO30828.1 - 1e-13 51.0 0.6 1.4e-13 50.5 0.4 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO30828.1 - 5.4e-10 38.7 0.4 7.7e-10 38.2 0.3 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.11 ETO30828.1 - 0.0038 17.1 0.1 0.0072 16.2 0.1 1.5 1 0 0 1 1 1 1 ABC1 family zinc_ribbon_2 PF13240.1 ETO30828.1 - 0.004 16.5 0.1 0.0081 15.6 0.1 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.1 ETO30828.1 - 0.0076 15.4 0.1 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 ETO30828.1 - 0.072 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-NADH-PPase PF09297.6 ETO30828.1 - 0.072 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain PH PF00169.24 ETO30828.1 - 0.076 13.2 0.3 0.16 12.1 0.2 1.5 1 1 0 1 1 1 0 PH domain RNA_POL_M_15KD PF02150.11 ETO30828.1 - 0.2 11.3 0.9 0.45 10.2 0.6 1.6 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit zf-RanBP PF00641.13 ETO30831.1 - 0.00022 20.2 4.3 0.00022 20.2 3.0 4.2 4 0 0 4 4 4 1 Zn-finger in Ran binding protein and others DinB_2 PF12867.2 ETO30831.1 - 0.072 13.4 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 DinB superfamily IBR PF01485.16 ETO30831.1 - 0.095 12.5 22.3 0.032 14.0 7.1 3.6 3 0 0 3 3 3 0 IBR domain Daxx PF03344.10 ETO30831.1 - 0.097 11.1 51.1 0.088 11.2 18.6 2.4 2 0 0 2 2 2 0 Daxx Family ZZ PF00569.12 ETO30832.1 - 0.0097 15.4 6.8 0.021 14.3 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type zf-UDP PF14569.1 ETO30832.1 - 0.011 15.5 0.5 0.094 12.4 0.6 2.2 2 0 0 2 2 2 0 Zinc-binding RING-finger PARP PF00644.15 ETO30832.1 - 0.035 13.5 0.3 0.1 11.9 0.2 1.9 1 1 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain C1_2 PF03107.11 ETO30832.1 - 0.12 12.4 8.9 0.11 12.6 4.4 2.2 2 0 0 2 2 2 0 C1 domain Tnp_zf-ribbon_2 PF13842.1 ETO30832.1 - 0.38 11.2 5.1 1.3 9.4 3.6 2.0 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon FYVE PF01363.16 ETO30832.1 - 0.74 9.7 8.4 0.16 11.8 3.0 2.0 1 1 1 2 2 2 0 FYVE zinc finger C1_3 PF07649.7 ETO30832.1 - 1.8 8.6 10.1 0.24 11.4 3.8 2.0 2 0 0 2 2 2 0 C1-like domain PUF PF00806.14 ETO30833.1 - 9.2e-49 160.2 15.9 7.9e-08 31.3 0.2 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat SSP160 PF06933.6 ETO30833.1 - 0.76 7.6 19.0 1.1 7.1 13.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Herpes_capsid PF06112.6 ETO30833.1 - 1.8 8.5 7.8 3.8 7.5 5.4 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein MSP1_C PF07462.6 ETO30833.1 - 4.4 5.5 5.6 7.1 4.8 3.9 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Pkinase PF00069.20 ETO30835.1 - 4.2e-42 144.1 0.0 4e-41 140.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO30835.1 - 2.6e-20 72.5 0.0 3.6e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO30835.1 - 0.0014 17.6 0.0 0.0027 16.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.19 ETO30835.1 - 0.0026 18.2 0.5 0.0043 17.5 0.3 1.4 1 0 0 1 1 1 1 Protein kinase C terminal domain DUF3889 PF13028.1 ETO30836.1 - 0.17 11.5 2.9 0.3 10.7 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3889) Myosin_TH1 PF06017.8 ETO30837.1 - 2.6e-15 56.2 4.6 4.7e-15 55.4 3.2 1.4 1 1 0 1 1 1 1 Myosin tail hSac2 PF12456.3 ETO30837.1 - 0.00018 20.9 0.1 0.00045 19.5 0.1 1.7 1 0 0 1 1 1 1 Inositol phosphatase Equine_IAV_S2 PF06502.6 ETO30838.1 - 0.046 13.5 0.5 0.25 11.2 0.1 2.1 2 0 0 2 2 2 0 Equine infectious anaemia virus S2 protein DUF3317 PF11779.3 ETO30838.1 - 0.31 10.4 2.0 0.49 9.8 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3317) Hid1 PF12722.2 ETO30838.1 - 4.8 4.7 8.1 5.5 4.5 5.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PDZ PF00595.19 ETO30839.1 - 0.00041 20.4 0.0 0.0038 17.3 0.0 2.2 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 ETO30839.1 - 0.00079 19.2 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain SAM_1 PF00536.25 ETO30839.1 - 0.0083 16.2 0.1 0.027 14.6 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO30839.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Ste50p-SAM PF09235.5 ETO30839.1 - 0.013 15.4 0.0 0.041 13.9 0.0 1.8 1 1 0 1 1 1 0 Ste50p, sterile alpha motif Pro_isomerase PF00160.16 ETO30840.1 - 8.9e-14 51.9 0.2 2.6e-13 50.4 0.0 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Kelch_6 PF13964.1 ETO30840.1 - 0.00023 21.1 1.8 1.7 8.9 0.1 3.7 2 1 1 3 3 3 2 Kelch motif IncA PF04156.9 ETO30840.1 - 0.0088 15.6 0.7 0.014 14.9 0.5 1.2 1 0 0 1 1 1 1 IncA protein DUF2899 PF11449.3 ETO30840.1 - 0.016 14.3 1.2 0.037 13.2 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2899) Kelch_5 PF13854.1 ETO30840.1 - 0.018 14.9 2.8 1.6 8.7 0.2 3.6 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.10 ETO30840.1 - 0.029 14.1 0.3 9.8 6.1 0.0 3.3 3 0 0 3 3 3 0 Kelch motif DUF676 PF05057.9 ETO30841.1 - 1.9e-24 86.1 0.2 3.2e-23 82.1 0.1 2.2 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PFEMP PF03011.10 ETO30841.1 - 0.089 13.1 0.1 0.18 12.1 0.0 1.6 2 0 0 2 2 2 0 PFEMP DBL domain PGAP1 PF07819.8 ETO30841.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Citrate_synt PF00285.16 ETO30842.1 - 2e-56 191.2 0.0 1e-55 188.9 0.0 1.8 1 1 0 1 1 1 1 Citrate synthase SDH_sah PF01972.11 ETO30842.1 - 0.048 12.4 0.6 0.53 9.0 0.1 2.0 2 0 0 2 2 2 0 Serine dehydrogenase proteinase Citrate_synt PF00285.16 ETO30843.1 - 7.9e-39 133.3 0.0 1e-38 132.9 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase DUF3906 PF13046.1 ETO30843.1 - 0.033 13.8 0.0 0.071 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3906) Gly-zipper_OmpA PF13436.1 ETO30845.1 - 0.098 12.3 8.9 0.022 14.3 2.3 2.5 2 1 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Coiled PF05710.7 ETO30845.1 - 4.8 7.7 10.3 6.7 7.2 3.5 2.4 1 1 1 2 2 2 0 Coiled coil DUF2963 PF11178.3 ETO30846.1 - 0.098 12.0 3.2 0.16 11.4 2.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2963) Ly49 PF08391.5 ETO30846.1 - 0.97 9.5 4.0 1 9.5 2.2 1.4 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region Reo_sigmaC PF04582.7 ETO30847.1 - 0.0016 17.7 7.1 0.015 14.5 0.6 2.1 1 1 0 2 2 2 1 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 ETO30847.1 - 0.01 15.6 11.1 0.44 10.3 2.2 2.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 ETO30847.1 - 0.025 14.1 50.6 0.044 13.3 11.6 3.0 1 1 2 3 3 3 0 IncA protein GAS PF13851.1 ETO30847.1 - 0.029 13.5 54.7 0.2 10.8 14.0 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Laminin_II PF06009.7 ETO30847.1 - 0.044 13.5 26.8 0.022 14.5 5.9 3.7 1 1 3 4 4 4 0 Laminin Domain II IFT57 PF10498.4 ETO30847.1 - 0.053 12.2 38.8 0.04 12.6 12.3 2.4 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 AAA_13 PF13166.1 ETO30847.1 - 0.064 11.7 33.1 0.12 10.7 22.9 1.5 1 1 0 1 1 1 0 AAA domain MCPsignal PF00015.16 ETO30847.1 - 0.073 12.6 12.8 0.25 10.8 3.8 2.6 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF869 PF05911.6 ETO30847.1 - 0.1 10.8 45.2 0.13 10.5 14.9 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) WEMBL PF05701.6 ETO30847.1 - 0.21 10.0 45.0 1.7 7.0 31.2 2.1 1 1 0 1 1 1 0 Weak chloroplast movement under blue light EzrA PF06160.7 ETO30847.1 - 0.28 9.3 42.3 0.0038 15.4 18.7 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA CENP-Q PF13094.1 ETO30847.1 - 0.68 9.9 48.9 0.93 9.5 7.1 3.4 1 1 2 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Hemerythrin PF01814.18 ETO30847.1 - 1.8 8.7 15.3 0.47 10.6 1.7 3.1 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain Mnd1 PF03962.10 ETO30847.1 - 3.3 7.3 45.9 28 4.2 12.4 3.6 1 1 1 2 2 2 0 Mnd1 family EAP30 PF04157.11 ETO30847.1 - 5.4 6.0 25.9 3.9 6.5 7.7 3.0 2 1 0 2 2 2 0 EAP30/Vps36 family Prominin PF05478.6 ETO30847.1 - 5.6 4.3 28.1 4.3 4.7 14.4 2.1 1 1 1 2 2 2 0 Prominin DUF3584 PF12128.3 ETO30847.1 - 6.2 4.0 48.4 4 4.6 14.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Cep57_CLD_2 PF14197.1 ETO30847.1 - 6.2 6.8 38.5 0.2 11.6 8.0 5.4 2 2 2 4 4 4 0 Centrosome localisation domain of PPC89 Z1 PF10593.4 ETO30847.1 - 6.4 5.9 19.5 6.8 5.8 3.5 2.4 1 1 1 2 2 2 0 Z1 domain NPV_P10 PF05531.7 ETO30847.1 - 6.8 7.0 17.7 2.9 8.2 1.4 3.8 1 1 3 4 4 4 0 Nucleopolyhedrovirus P10 protein APG6 PF04111.7 ETO30847.1 - 8.2 5.3 53.1 0.35 9.8 11.1 3.0 1 1 2 3 3 3 0 Autophagy protein Apg6 ADIP PF11559.3 ETO30847.1 - 8.5 6.2 46.7 1.5 8.7 12.3 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.6 ETO30847.1 - 9.5 4.7 43.4 2.7 6.5 12.4 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein Laminin_I PF06008.9 ETO30847.1 - 9.8 5.3 42.4 2.1 7.5 13.7 2.9 1 1 1 2 2 2 0 Laminin Domain I Kinesin PF00225.18 ETO30848.1 - 0.0014 17.3 0.0 0.0039 15.9 0.0 1.6 1 1 0 1 1 1 1 Kinesin motor domain DUF3450 PF11932.3 ETO30849.1 - 0.025 13.8 1.0 0.044 13.0 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) eRF1_3 PF03465.10 ETO30849.1 - 0.31 11.3 2.0 25 5.1 0.1 3.0 2 1 0 2 2 2 0 eRF1 domain 3 PEPCK PF00821.13 ETO30850.1 - 8.1e-206 684.7 0.1 7.3e-172 572.5 0.0 2.2 2 0 0 2 2 2 2 Phosphoenolpyruvate carboxykinase FliE PF02049.13 ETO30851.1 - 0.087 12.8 8.9 0.22 11.5 6.0 1.8 1 1 1 2 2 2 0 Flagellar hook-basal body complex protein FliE DUF2201_N PF13203.1 ETO30851.1 - 0.85 8.7 6.6 1 8.4 4.6 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Neur_chan_memb PF02932.11 ETO30851.1 - 0.95 9.2 6.7 1.2 9.0 4.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MDFI PF15316.1 ETO30851.1 - 3.2 7.7 6.6 4.6 7.1 4.6 1.3 1 0 0 1 1 1 0 MyoD family inhibitor UTP15_C PF09384.5 ETO30852.1 - 3.6e-19 68.9 0.0 4.8e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 UTP15 C terminal RCC1 PF00415.13 ETO30853.1 - 4.9e-40 135.5 20.4 4.5e-08 33.1 0.0 8.2 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO30853.1 - 3.5e-29 99.7 28.9 4.8e-07 29.2 0.3 7.2 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.1 ETO30853.1 - 0.045 13.5 0.3 26 4.5 0.0 3.2 2 1 1 3 3 3 0 SUKH-3 immunity protein TPR_12 PF13424.1 ETO30854.1 - 2.7e-06 27.2 1.4 6.3e-06 26.0 0.2 2.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO30854.1 - 0.0046 16.6 0.2 1.4 8.8 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETO30854.1 - 0.0063 16.4 0.0 0.54 10.2 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO30854.1 - 0.086 12.4 1.2 0.19 11.3 0.2 2.1 2 0 0 2 2 2 0 TPR repeat TPR_1 PF00515.23 ETO30854.1 - 0.47 10.1 2.7 7.3 6.3 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETO30854.1 - 1.9 8.6 5.5 19 5.4 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat YEATS PF03366.11 ETO30855.1 - 1.1e-23 82.7 0.1 2.7e-23 81.4 0.0 1.7 1 0 0 1 1 1 1 YEATS family PhyH PF05721.8 ETO30856.1 - 0.001 19.1 0.0 0.32 11.0 0.0 2.5 2 1 1 3 3 3 2 Phytanoyl-CoA dioxygenase (PhyH) Longin PF13774.1 ETO30857.1 - 1.4e-18 66.1 0.5 3.6e-18 64.8 0.4 1.7 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 ETO30857.1 - 5.5e-10 38.7 0.3 5.5e-10 38.7 0.2 2.3 3 0 0 3 3 3 1 Synaptobrevin PX PF00787.19 ETO30857.1 - 2.7e-07 30.3 0.0 7.9e-07 28.8 0.0 1.8 1 0 0 1 1 1 1 PX domain Vfa1 PF08432.5 ETO30857.1 - 0.00063 19.8 8.4 0.00063 19.8 5.8 2.2 1 1 1 2 2 2 1 AAA-ATPase Vps4-associated protein 1 Macoilin PF09726.4 ETO30857.1 - 0.35 9.1 17.0 0.55 8.4 11.8 1.2 1 0 0 1 1 1 0 Transmembrane protein Flu_B_M2 PF04772.7 ETO30857.1 - 1.1 9.3 5.4 1.2 9.1 0.1 3.3 3 0 0 3 3 3 0 Influenza B matrix protein 2 (BM2) DUF4381 PF14316.1 ETO30858.1 - 0.027 14.5 0.6 0.047 13.7 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF2231 PF09990.4 ETO30858.1 - 0.033 14.5 0.2 0.056 13.7 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) DUF912 PF06024.7 ETO30859.1 - 0.0088 16.0 0.4 0.0088 16.0 0.3 2.1 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) RRN3 PF05327.6 ETO30859.1 - 0.048 11.7 1.3 0.055 11.5 0.9 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ECIST_Cterm PF14784.1 ETO30859.1 - 0.11 12.4 6.5 0.24 11.3 3.8 1.8 2 0 0 2 2 2 0 C-terminal domain of the ECSIT protein CDC45 PF02724.9 ETO30859.1 - 0.32 8.9 1.7 0.3 9.0 1.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 ETO30859.1 - 0.81 8.1 9.7 0.95 7.8 6.7 1.1 1 0 0 1 1 1 0 Daxx Family TMCO5 PF14992.1 ETO30859.1 - 5.4 6.0 12.9 1.6 7.7 0.4 2.1 2 0 0 2 2 2 0 TMCO5 family Nro1 PF12753.2 ETO30859.1 - 6.6 5.5 12.6 3 6.6 7.3 1.4 2 0 0 2 2 2 0 Nuclear pore complex subunit Nro1 DUF2890 PF11081.3 ETO30859.1 - 7.9 6.4 13.8 5.6 6.9 8.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Tropomyosin_1 PF12718.2 ETO30860.1 - 0.0085 15.9 12.7 0.01 15.7 1.0 2.2 2 0 0 2 2 2 1 Tropomyosin like DivIC PF04977.10 ETO30860.1 - 0.016 14.6 6.3 0.22 11.0 0.5 2.3 2 0 0 2 2 2 0 Septum formation initiator TMF_DNA_bd PF12329.3 ETO30860.1 - 0.046 13.5 13.4 0.14 11.9 2.6 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 ETO30860.1 - 0.053 13.3 4.8 0.14 11.9 3.3 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) FliJ PF02050.11 ETO30860.1 - 0.064 13.3 8.0 0.48 10.4 1.0 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein KLRAQ PF10205.4 ETO30860.1 - 0.11 12.5 7.1 0.1 12.6 0.4 2.4 1 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein BBP1_C PF15272.1 ETO30860.1 - 0.19 11.2 11.2 0.039 13.4 2.3 2.0 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal NPV_P10 PF05531.7 ETO30860.1 - 0.2 11.9 4.8 2.8 8.2 0.0 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Exonuc_VII_S PF02609.11 ETO30860.1 - 0.26 11.1 9.3 0.11 12.3 1.0 2.6 3 0 0 3 3 2 0 Exonuclease VII small subunit Occludin_ELL PF07303.8 ETO30860.1 - 0.3 11.8 5.5 0.25 12.0 1.2 2.2 2 0 0 2 2 2 0 Occludin homology domain DUF2408 PF10303.4 ETO30860.1 - 0.34 11.0 7.2 0.48 10.5 0.2 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2408) Snapin_Pallidin PF14712.1 ETO30860.1 - 0.4 11.0 7.6 0.82 10.0 0.2 2.3 2 0 0 2 2 2 0 Snapin/Pallidin priB_priC PF07445.7 ETO30860.1 - 0.42 10.0 6.4 0.46 9.9 0.4 2.1 1 1 1 2 2 2 0 Primosomal replication protein priB and priC Cob_adeno_trans PF01923.13 ETO30860.1 - 0.43 10.3 2.9 7.7 6.2 0.1 2.2 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DUF3847 PF12958.2 ETO30860.1 - 0.44 10.3 7.1 1.9 8.3 1.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3847) DivIVA PF05103.8 ETO30860.1 - 0.58 10.2 8.7 0.28 11.2 0.4 2.1 2 0 0 2 2 2 0 DivIVA protein KIF1B PF12423.3 ETO30860.1 - 0.58 10.2 3.3 0.39 10.8 0.9 1.8 2 0 0 2 2 2 0 Kinesin protein 1B Microtub_assoc PF07989.6 ETO30860.1 - 0.58 10.0 9.1 0.18 11.6 0.6 2.5 2 1 0 2 2 2 0 Microtubule associated Striatin PF08232.7 ETO30860.1 - 0.58 10.4 6.9 1.7 8.9 0.5 2.1 2 0 0 2 2 2 0 Striatin family IncA PF04156.9 ETO30860.1 - 0.65 9.5 7.7 2.2 7.8 1.0 2.1 2 0 0 2 2 2 0 IncA protein Nop25 PF09805.4 ETO30860.1 - 1.2 9.2 7.0 2 8.4 0.6 2.1 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Ax_dynein_light PF10211.4 ETO30860.1 - 1.3 8.7 9.3 1.4 8.7 2.3 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain Med9 PF07544.8 ETO30860.1 - 1.5 8.6 6.1 0.44 10.3 0.8 2.3 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Remorin_C PF03763.8 ETO30860.1 - 1.5 8.3 8.6 2.7 7.5 1.0 2.2 2 0 0 2 2 2 0 Remorin, C-terminal region TBPIP PF07106.8 ETO30860.1 - 2.6 7.5 12.3 3 7.3 2.2 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TACC PF05010.9 ETO30860.1 - 2.9 7.6 10.8 2 8.1 1.8 2.1 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) Spc24 PF08286.6 ETO30860.1 - 3.1 7.5 15.0 4.7 6.9 4.3 2.3 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 CR6_interact PF10147.4 ETO30860.1 - 4 6.6 7.4 0.33 10.2 1.2 1.9 2 0 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF972 PF06156.8 ETO30860.1 - 4.2 7.7 11.1 4.6 7.6 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) CCDC-167 PF15188.1 ETO30860.1 - 6.8 6.7 11.1 2.6 8.0 1.6 2.7 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 GPCR_chapero_1 PF11904.3 ETO30861.1 - 0.37 9.9 7.8 0.94 8.5 5.4 1.7 1 0 0 1 1 1 0 GPCR-chaperone ATP-synt_G PF04718.10 ETO30862.1 - 0.0011 19.6 0.0 0.0022 18.6 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit WD40 PF00400.27 ETO30863.1 - 8.8e-38 126.8 7.7 1.8e-11 43.4 0.1 5.1 5 1 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO30863.1 - 5.8e-08 31.3 0.6 0.2 9.7 0.0 3.7 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO30863.1 - 0.0013 17.6 3.3 0.061 12.0 1.5 2.8 1 1 2 3 3 3 2 Nup133 N terminal like RelA_SpoT PF04607.12 ETO30864.1 - 0.022 14.7 0.1 0.082 12.9 0.0 2.0 1 0 0 1 1 1 0 Region found in RelA / SpoT proteins Peptidase_C48 PF02902.14 ETO30865.1 - 1.1e-27 97.1 8.1 1.1e-27 97.1 5.6 2.2 2 1 1 3 3 3 1 Ulp1 protease family, C-terminal catalytic domain Kelch_4 PF13418.1 ETO30866.1 - 9.3e-11 41.3 1.5 7.9e-06 25.5 0.0 5.9 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO30866.1 - 1.3e-07 31.4 8.7 0.011 15.9 0.1 7.0 7 0 0 7 7 7 1 Kelch motif Kelch_1 PF01344.20 ETO30866.1 - 6.2e-07 28.8 5.2 0.00024 20.5 0.3 4.9 6 0 0 6 6 6 2 Kelch motif Kelch_3 PF13415.1 ETO30866.1 - 1.2e-06 28.4 4.2 0.021 14.9 0.0 6.0 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO30866.1 - 3.7e-06 26.7 3.6 0.085 12.8 0.1 4.9 4 0 0 4 4 4 2 Kelch motif BBS2_N PF14781.1 ETO30866.1 - 0.032 13.8 0.1 0.38 10.3 0.0 2.9 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal UCH PF00443.24 ETO30867.1 - 1.8e-40 138.7 21.9 1.8e-40 138.7 15.2 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO30867.1 - 5.4e-15 55.6 7.3 2.6e-10 40.2 2.1 4.5 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUF3439 PF11921.3 ETO30868.1 - 0.058 13.1 3.5 0.11 12.2 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 ETO30868.1 - 0.9 7.4 7.6 1.2 6.9 5.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Exo_endo_phos PF03372.18 ETO30869.1 - 2e-14 54.1 1.1 3.7e-14 53.2 0.8 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TTL PF03133.10 ETO30870.1 - 5e-25 88.0 5.2 1.6e-23 83.0 1.1 3.2 2 2 1 3 3 3 1 Tubulin-tyrosine ligase family Mito_carr PF00153.22 ETO30871.1 - 2.2e-33 113.7 4.3 6.6e-14 51.3 0.0 3.4 3 1 1 4 4 4 3 Mitochondrial carrier protein DUF3176 PF11374.3 ETO30871.1 - 0.0084 15.9 1.1 1.4 8.8 0.0 2.4 1 1 0 2 2 2 2 Protein of unknown function (DUF3176) OSTbeta PF15048.1 ETO30871.1 - 0.032 14.3 0.0 0.067 13.2 0.0 1.5 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF1473 PF07341.6 ETO30871.1 - 0.11 12.0 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1473) Glyco_hydro_31 PF01055.21 ETO30872.1 - 4.3e-09 35.7 0.2 6.6e-09 35.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Acid_phosphat_B PF03767.9 ETO30872.1 - 0.024 13.9 0.1 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Myosin_N PF02736.14 ETO30872.1 - 0.11 12.2 0.0 7.9 6.2 0.0 2.4 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Cyclin_N PF00134.18 ETO30873.1 - 1.3e-11 44.1 3.6 2.4e-09 36.8 0.9 2.8 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 ETO30873.1 - 1.7e-09 37.6 2.1 4.1e-09 36.3 0.1 2.6 3 0 0 3 3 3 1 Cyclin, C-terminal domain MutS_V PF00488.16 ETO30875.1 - 1.1e-28 100.2 0.0 1.2e-28 100.1 0.0 1.0 1 0 0 1 1 1 1 MutS domain V MutS_V PF00488.16 ETO30876.1 - 7.8e-41 140.0 0.2 1.1e-40 139.5 0.1 1.1 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 ETO30876.1 - 0.0014 18.4 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 MutS domain III AAA_29 PF13555.1 ETO30876.1 - 0.0024 17.3 0.0 0.0042 16.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 ETO30876.1 - 0.13 12.6 0.1 0.59 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain TACC PF05010.9 ETO30879.1 - 4.7e-05 23.2 15.6 4.7e-05 23.2 10.8 2.4 1 1 1 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC) FUSC PF04632.7 ETO30879.1 - 2.5 6.4 6.4 0.8 8.0 0.6 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family CALCOCO1 PF07888.6 ETO30879.1 - 2.9 6.0 42.5 0.15 10.3 13.6 2.1 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Reo_sigmaC PF04582.7 ETO30879.1 - 3.7 6.6 17.3 2.3 7.3 2.6 3.3 1 1 2 4 4 4 0 Reovirus sigma C capsid protein WEMBL PF05701.6 ETO30879.1 - 8.1 4.7 56.9 13 4.0 38.4 1.9 1 1 0 1 1 1 0 Weak chloroplast movement under blue light DUF4201 PF13870.1 ETO30880.1 - 0.0029 17.0 11.6 0.0029 17.0 8.1 4.7 4 1 1 5 5 5 1 Domain of unknown function (DUF4201) DUF948 PF06103.6 ETO30880.1 - 0.0052 16.6 1.7 0.0052 16.6 1.2 6.5 4 3 2 6 6 6 1 Bacterial protein of unknown function (DUF948) DivIC PF04977.10 ETO30880.1 - 0.13 11.7 0.1 0.13 11.7 0.1 8.2 4 2 5 9 9 9 0 Septum formation initiator Reo_sigmaC PF04582.7 ETO30880.1 - 0.29 10.2 24.8 0.34 10.0 1.8 3.6 2 2 1 3 3 3 0 Reovirus sigma C capsid protein GAS PF13851.1 ETO30880.1 - 6.4 5.9 93.8 0.0095 15.1 17.9 5.0 2 2 3 5 5 5 0 Growth-arrest specific micro-tubule binding WD40 PF00400.27 ETO30881.1 - 8.2e-161 516.9 42.5 2.2e-12 46.3 0.7 15.0 14 1 1 15 15 15 14 WD domain, G-beta repeat PD40 PF07676.7 ETO30881.1 - 3.1e-11 42.6 25.8 0.91 9.2 0.0 12.1 12 0 0 12 12 12 2 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO30881.1 - 1.6e-10 39.7 22.3 0.21 9.6 0.0 10.7 1 1 7 10 10 10 5 Nucleoporin Nup120/160 DUF1258 PF06869.7 ETO30881.1 - 1.9e-09 37.0 1.9 0.45 9.5 0.1 7.2 4 2 4 8 8 8 4 Protein of unknown function (DUF1258) DUF1652 PF07865.6 ETO30881.1 - 1.7e-07 30.7 0.0 6.3 6.4 0.0 8.5 10 1 1 11 11 11 1 Protein of unknown function (DUF1652) Nbas_N PF15492.1 ETO30881.1 - 3.8e-06 26.2 9.5 0.23 10.5 0.0 7.1 2 2 3 7 7 7 2 Neuroblastoma-amplified sequence, N terminal Pentapeptide_4 PF13599.1 ETO30881.1 - 5.2e-06 26.1 0.1 2e-05 24.3 0.1 2.0 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETO30881.1 - 6.5e-06 25.2 0.9 1.7e-05 23.9 0.6 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Cytochrom_D1 PF02239.11 ETO30881.1 - 0.0015 16.9 9.6 1.2 7.3 0.0 5.3 1 1 5 6 6 6 1 Cytochrome D1 heme domain Pentapeptide_3 PF13576.1 ETO30881.1 - 0.0017 18.2 1.5 0.0077 16.0 1.0 2.2 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Mid2 PF04478.7 ETO30881.1 - 0.003 16.9 3.5 5.4 6.3 0.0 6.2 5 1 1 7 7 7 1 Mid2 like cell wall stress sensor Microtub_assoc PF07989.6 ETO30881.1 - 0.41 10.5 2.7 8.9 6.2 0.1 2.5 2 0 0 2 2 2 0 Microtubule associated Resistin PF06954.6 ETO30881.1 - 2.7 8.3 6.5 1.3e+02 2.9 0.0 5.3 5 2 1 7 7 6 0 Resistin DNA_alkylation PF08713.6 ETO30882.1 - 1e-32 113.3 0.6 2.9e-32 111.9 0.4 1.7 1 1 0 1 1 1 1 DNA alkylation repair enzyme Spc24 PF08286.6 ETO30883.1 - 0.0049 16.5 8.7 0.35 10.5 3.8 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 EIF4E-T PF10477.4 ETO30883.1 - 0.0051 15.6 1.7 0.0058 15.4 1.2 1.0 1 0 0 1 1 1 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E PspA_IM30 PF04012.7 ETO30883.1 - 0.012 14.9 9.2 0.015 14.6 6.4 1.1 1 0 0 1 1 1 0 PspA/IM30 family CDC37_N PF03234.9 ETO30883.1 - 0.014 15.7 8.4 0.016 15.5 5.8 1.0 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding AAA_13 PF13166.1 ETO30883.1 - 0.025 13.0 5.9 0.032 12.6 4.1 1.2 1 0 0 1 1 1 0 AAA domain CENP-F_leu_zip PF10473.4 ETO30883.1 - 0.028 14.2 14.6 0.22 11.3 6.6 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 ETO30883.1 - 0.029 13.8 9.7 0.035 13.5 6.7 1.1 1 0 0 1 1 1 0 Intermediate filament protein Myosin_tail_1 PF01576.14 ETO30883.1 - 0.031 12.0 16.3 0.046 11.4 6.3 2.0 1 1 1 2 2 2 0 Myosin tail DUF1852 PF08908.6 ETO30883.1 - 0.068 11.9 0.0 0.075 11.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1852) Pox_A_type_inc PF04508.7 ETO30883.1 - 0.074 12.8 1.6 0.074 12.8 1.1 4.5 3 2 0 4 4 4 0 Viral A-type inclusion protein repeat GlutR_dimer PF00745.15 ETO30883.1 - 0.082 12.8 7.0 0.19 11.6 4.7 1.7 1 1 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain Fib_alpha PF08702.5 ETO30883.1 - 0.094 12.8 6.9 0.12 12.5 4.8 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ERM PF00769.14 ETO30883.1 - 0.11 11.9 19.0 0.14 11.7 13.2 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family AAA_32 PF13654.1 ETO30883.1 - 0.12 10.9 7.4 0.14 10.7 5.2 1.1 1 0 0 1 1 1 0 AAA domain SF-assemblin PF06705.6 ETO30883.1 - 0.13 11.4 11.5 0.16 11.0 8.0 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin DUF2664 PF10867.3 ETO30883.1 - 0.22 12.1 5.5 0.72 10.5 3.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2664) LXG PF04740.7 ETO30883.1 - 0.24 11.1 8.3 0.35 10.6 2.1 1.9 1 1 1 2 2 2 0 LXG domain of WXG superfamily YscO PF07321.7 ETO30883.1 - 0.26 11.0 12.1 0.66 9.7 8.3 1.7 1 1 0 1 1 1 0 Type III secretion protein YscO DZF PF07528.9 ETO30883.1 - 0.27 10.6 1.4 0.32 10.3 1.0 1.0 1 0 0 1 1 1 0 DZF domain TMPIT PF07851.8 ETO30883.1 - 0.3 10.0 5.1 0.38 9.7 3.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein Bcr-Abl_Oligo PF09036.5 ETO30883.1 - 0.31 11.0 6.0 0.72 9.8 2.7 2.4 1 1 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Ax_dynein_light PF10211.4 ETO30883.1 - 0.33 10.7 12.5 1.4 8.7 4.9 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain SlyX PF04102.7 ETO30883.1 - 0.39 11.1 8.4 5.8 7.3 2.6 2.2 2 0 0 2 2 2 0 SlyX Vfa1 PF08432.5 ETO30883.1 - 0.39 10.7 7.4 0.51 10.3 5.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CALCOCO1 PF07888.6 ETO30883.1 - 0.41 8.8 10.5 0.54 8.4 7.3 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF342 PF03961.8 ETO30883.1 - 0.42 8.9 9.1 0.51 8.6 6.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) HR1 PF02185.11 ETO30883.1 - 0.42 10.3 12.9 3.1 7.6 0.8 2.6 1 1 1 2 2 2 0 Hr1 repeat TMCO5 PF14992.1 ETO30883.1 - 0.58 9.2 10.8 0.6 9.1 7.0 1.3 1 1 0 1 1 1 0 TMCO5 family PHTB1_C PF14728.1 ETO30883.1 - 0.59 8.8 5.4 0.7 8.6 3.8 1.0 1 0 0 1 1 1 0 PTHB1 C-terminus DASH_Spc34 PF08657.5 ETO30883.1 - 0.61 9.7 10.1 0.8 9.3 7.0 1.2 1 0 0 1 1 1 0 DASH complex subunit Spc34 Striatin PF08232.7 ETO30883.1 - 0.62 10.3 11.0 2.9 8.2 7.6 2.1 1 1 0 1 1 1 0 Striatin family HAUS5 PF14817.1 ETO30883.1 - 0.64 8.4 13.9 0.79 8.1 9.6 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Cauli_AT PF03233.8 ETO30883.1 - 0.66 9.6 4.6 0.44 10.2 1.4 1.7 1 1 1 2 2 2 0 Aphid transmission protein Mnd1 PF03962.10 ETO30883.1 - 0.75 9.4 11.6 2.3 7.8 8.1 1.7 1 1 0 1 1 1 0 Mnd1 family DUF4404 PF14357.1 ETO30883.1 - 0.77 10.2 10.7 0.17 12.3 4.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) RBD-FIP PF09457.5 ETO30883.1 - 0.96 9.3 10.2 1.2 9.0 1.6 2.9 2 1 1 3 3 3 0 FIP domain Seryl_tRNA_N PF02403.17 ETO30883.1 - 0.98 9.4 8.8 6.2 6.8 5.3 2.1 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain RRF PF01765.14 ETO30883.1 - 1 8.7 7.6 1.8 8.0 5.2 1.3 1 0 0 1 1 1 0 Ribosome recycling factor BBP1_C PF15272.1 ETO30883.1 - 1.1 8.8 13.8 2 7.9 1.3 2.1 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal Ribonuc_2-5A PF06479.7 ETO30883.1 - 1.1 9.1 4.2 5.1 6.9 2.9 2.0 1 1 0 1 1 1 0 Ribonuclease 2-5A BRE1 PF08647.6 ETO30883.1 - 1.1 9.2 11.4 0.45 10.5 5.0 2.0 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DivIC PF04977.10 ETO30883.1 - 1.1 8.7 10.2 1.5 8.3 1.9 2.4 1 1 1 2 2 2 0 Septum formation initiator Atg14 PF10186.4 ETO30883.1 - 1.2 8.0 14.0 10 4.9 9.5 1.9 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DASH_Hsk3 PF08227.6 ETO30883.1 - 1.2 9.3 0.1 1.2 9.3 0.1 3.4 4 0 0 4 4 3 0 DASH complex subunit Hsk3 like V_ATPase_I PF01496.14 ETO30883.1 - 1.2 6.8 6.2 0.83 7.4 2.7 1.3 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Spc7 PF08317.6 ETO30883.1 - 1.4 7.4 12.2 2.3 6.7 8.4 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4615 PF15393.1 ETO30883.1 - 1.6 8.9 6.6 6.3 7.0 0.4 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4615) Phage_GP20 PF06810.6 ETO30883.1 - 1.8 7.9 8.5 2.2 7.6 0.4 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 Asp-B-Hydro_N PF05279.6 ETO30883.1 - 2 8.2 7.2 2.2 8.0 5.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2968 PF11180.3 ETO30883.1 - 2 7.7 10.3 1.7 8.0 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) OmpH PF03938.9 ETO30883.1 - 2.2 8.1 10.4 2.9 7.8 7.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) IncA PF04156.9 ETO30883.1 - 2.4 7.7 15.8 9.1 5.8 11.0 1.7 1 1 0 1 1 1 0 IncA protein APG6 PF04111.7 ETO30883.1 - 2.8 6.9 10.9 4 6.4 7.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Prefoldin_2 PF01920.15 ETO30883.1 - 2.9 7.6 12.6 5.7 6.7 3.2 2.3 1 1 0 2 2 2 0 Prefoldin subunit DUF4094 PF13334.1 ETO30883.1 - 3.3 8.1 6.1 14 6.1 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) TMF_DNA_bd PF12329.3 ETO30883.1 - 3.3 7.5 14.4 3.6 7.4 0.6 2.3 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TBPIP PF07106.8 ETO30883.1 - 3.4 7.2 10.8 2.3 7.7 4.0 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Rabaptin PF03528.10 ETO30883.1 - 3.8 7.4 13.1 0.98 9.3 5.5 2.0 1 1 1 2 2 2 0 Rabaptin CENP-Q PF13094.1 ETO30883.1 - 3.9 7.4 19.1 4.8 7.1 0.9 2.0 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit GrpE PF01025.14 ETO30883.1 - 4 6.9 10.0 6.3 6.3 6.4 1.6 1 1 0 1 1 1 0 GrpE Sec2p PF06428.6 ETO30883.1 - 4.1 7.3 11.2 2.9 7.8 3.5 2.1 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Zein-binding PF04576.10 ETO30883.1 - 4.1 7.5 14.5 9 6.4 9.1 2.0 1 1 1 2 2 2 0 Zein-binding Nsp1_C PF05064.8 ETO30883.1 - 4.6 6.9 8.3 8.6 6.0 1.3 2.1 1 1 1 2 2 2 0 Nsp1-like C-terminal region HlyD PF00529.15 ETO30883.1 - 4.9 6.3 7.2 12 5.1 5.0 1.6 1 1 0 1 1 1 0 HlyD family secretion protein YlqD PF11068.3 ETO30883.1 - 5 7.1 11.3 32 4.5 7.8 1.9 1 1 0 1 1 1 0 YlqD protein Exonuc_VII_L PF02601.10 ETO30883.1 - 5.8 6.0 8.1 6.8 5.7 5.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.1 ETO30883.1 - 6.8 5.5 6.2 10 4.9 4.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Uso1_p115_C PF04871.8 ETO30883.1 - 7.7 6.4 14.7 43 4.0 10.2 1.9 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Tho2 PF11262.3 ETO30883.1 - 8 5.4 9.2 3 6.8 3.3 1.9 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF972 PF06156.8 ETO30883.1 - 8.4 6.7 10.4 6.9 7.0 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DivIVA PF05103.8 ETO30883.1 - 9.7 6.2 10.9 20 5.2 7.5 1.6 1 1 0 1 1 1 0 DivIVA protein TPR_12 PF13424.1 ETO30884.1 - 7.5e-69 227.6 12.4 2.3e-22 78.7 0.1 4.3 3 1 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO30884.1 - 2.5e-53 175.5 44.0 5.9e-11 41.4 1.1 7.1 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.1 ETO30884.1 - 2.2e-48 160.8 0.0 9.5e-08 31.7 0.0 7.0 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.1 ETO30884.1 - 7.2e-44 147.2 24.7 5.2e-16 58.0 3.8 4.8 3 1 1 4 4 4 4 TPR repeat TPR_2 PF07719.12 ETO30884.1 - 2e-39 130.3 28.5 9.9e-08 31.3 0.2 7.1 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.1 ETO30884.1 - 2.4e-39 130.0 9.0 9.6e-07 28.1 0.0 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETO30884.1 - 7.5e-34 112.9 46.8 5.5e-08 32.0 1.2 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.1 ETO30884.1 - 1.7e-18 65.1 23.3 0.0024 17.9 0.1 7.6 7 2 0 7 7 6 5 Tetratricopeptide repeat SNAP PF14938.1 ETO30884.1 - 4.9e-18 65.2 6.3 5.7e-10 38.8 0.3 3.1 2 1 1 3 3 3 2 Soluble NSF attachment protein, SNAP TPR_14 PF13428.1 ETO30884.1 - 1.3e-13 50.2 0.0 0.23 12.2 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO30884.1 - 9.4e-13 47.7 7.5 0.13 12.7 0.0 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO30884.1 - 2.6e-12 47.0 0.0 0.007 17.0 0.0 4.5 4 2 0 4 4 4 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO30884.1 - 7.1e-10 37.9 6.6 2 7.6 0.0 7.0 7 0 0 7 7 7 3 SHNi-TPR MIT PF04212.13 ETO30884.1 - 3.2e-09 36.5 17.8 0.051 13.4 0.2 6.8 7 0 0 7 7 7 2 MIT (microtubule interacting and transport) domain PPR PF01535.15 ETO30884.1 - 2.6e-07 30.1 5.1 0.76 9.8 0.0 5.9 6 0 0 6 6 6 1 PPR repeat Apc3 PF12895.2 ETO30884.1 - 2.8e-07 30.5 19.5 0.0012 18.9 1.0 4.7 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO30884.1 - 2.3e-06 27.8 3.2 0.41 11.0 0.0 4.7 3 1 2 5 5 5 1 Tetratricopeptide repeat DUF2225 PF09986.4 ETO30884.1 - 0.00065 19.2 15.1 0.18 11.2 1.4 4.0 1 1 3 4 4 4 3 Uncharacterized protein conserved in bacteria (DUF2225) ENT PF03735.9 ETO30884.1 - 0.0021 17.7 0.2 0.21 11.3 0.0 3.0 3 0 0 3 3 3 1 ENT domain Toxin_13 PF07822.6 ETO30884.1 - 0.0036 17.1 11.9 10 6.1 0.1 5.0 5 0 0 5 5 5 0 Neurotoxin B-IV-like protein DUF4093 PF13331.1 ETO30884.1 - 0.004 17.3 2.1 14 5.9 0.1 5.5 3 3 3 6 6 6 0 Domain of unknown function (DUF4093) RPN7 PF10602.4 ETO30884.1 - 0.0061 15.9 12.1 0.024 13.9 2.5 4.0 2 2 2 4 4 4 1 26S proteasome subunit RPN7 DUF627 PF04781.7 ETO30884.1 - 0.0079 15.8 9.0 4.3 6.9 0.0 4.8 2 1 4 6 6 6 1 Protein of unknown function (DUF627) DUF386 PF04074.7 ETO30884.1 - 0.012 15.1 6.1 0.38 10.2 0.5 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF386) TPR_3 PF07720.7 ETO30884.1 - 0.019 14.7 18.8 0.2 11.4 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Sel1 PF08238.7 ETO30884.1 - 0.053 14.1 9.6 45 4.8 0.0 5.7 6 0 0 6 6 6 0 Sel1 repeat Tat PF00539.13 ETO30884.1 - 0.12 11.9 1.5 22 4.7 0.0 3.4 3 0 0 3 3 3 0 Transactivating regulatory protein (Tat) DUF520 PF04461.8 ETO30884.1 - 0.12 12.1 2.5 0.5 10.2 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF520) Cytochrom_CIII PF02085.11 ETO30884.1 - 0.39 10.8 2.2 0.91 9.6 0.2 2.4 2 1 0 3 3 2 0 Class III cytochrome C family NSF PF02071.15 ETO30884.1 - 0.85 10.4 20.5 25 6.0 0.1 7.0 7 0 0 7 7 6 0 Aromatic-di-Alanine (AdAR) repeat ATP-synt_E_2 PF08112.6 ETO30884.1 - 6 7.0 17.7 41 4.3 0.0 6.5 7 0 0 7 7 7 0 ATP synthase epsilon subunit Clathrin PF00637.15 ETO30884.1 - 7.6 6.1 19.8 4.5 6.8 1.0 5.1 2 1 2 5 5 5 0 Region in Clathrin and VPS Shisa PF13908.1 ETO30885.1 - 0.00019 21.6 2.2 0.00019 21.6 1.5 2.0 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator SDA1 PF05285.7 ETO30885.1 - 0.0022 17.3 20.5 0.0022 17.3 14.2 1.9 1 1 1 2 2 2 1 SDA1 Mem_trans PF03547.13 ETO30885.1 - 0.36 9.0 15.5 0.04 12.2 2.4 2.2 1 1 1 2 2 2 0 Membrane transport protein Mucin PF01456.12 ETO30885.1 - 1.4 8.6 6.1 0.23 11.2 1.6 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF4199 PF13858.1 ETO30885.1 - 1.7 8.5 6.5 15 5.4 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) FAM163 PF15069.1 ETO30885.1 - 6.5 7.3 17.0 0.031 14.8 4.7 2.4 2 2 1 3 3 3 0 FAM163 family EF-hand_1 PF00036.27 ETO30886.1 - 2.1e-28 95.3 13.2 2.5e-07 29.5 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.1 ETO30886.1 - 9.6e-26 87.9 8.6 1.8e-06 27.0 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 ETO30886.1 - 5.9e-24 83.9 4.5 2.1e-12 46.9 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO30886.1 - 6.7e-23 78.4 11.4 1.7e-06 27.4 0.2 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 ETO30886.1 - 2.7e-17 62.1 7.6 4e-06 26.3 0.2 4.4 3 2 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 ETO30886.1 - 2.7e-11 43.4 1.2 6.9e-05 22.8 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 ETO30886.1 - 0.0015 18.1 4.9 6.1 6.5 0.0 4.1 3 1 0 4 4 4 2 EF hand EF-hand_like PF09279.6 ETO30886.1 - 0.0056 16.6 0.8 0.093 12.7 0.0 2.5 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like KIP1 PF07765.7 ETO30886.1 - 0.011 15.5 0.1 0.26 11.1 0.0 2.6 2 1 0 2 2 2 0 KIP1-like protein EF-hand_9 PF14658.1 ETO30886.1 - 0.036 13.9 1.9 14 5.6 0.1 3.7 3 1 0 3 3 3 0 EF-hand domain EF-hand_4 PF12763.2 ETO30886.1 - 0.18 11.5 5.9 0.54 10.0 0.1 3.1 1 1 3 4 4 4 0 Cytoskeletal-regulatory complex EF hand SusD-like_3 PF14322.1 ETO30887.1 - 3.6 7.6 28.5 0.13 12.2 3.8 2.3 2 0 0 2 2 2 0 Starch-binding associating with outer membrane Late_protein_L2 PF00513.13 ETO30887.1 - 6 5.5 7.8 7.6 5.2 4.2 1.8 1 1 1 2 2 2 0 Late Protein L2 Dynein_heavy PF03028.10 ETO30888.1 - 2.5e-84 283.6 1.1 4.3e-84 282.9 0.7 1.3 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_9 PF12781.2 ETO30888.1 - 1.7e-32 112.1 0.1 3.9e-32 110.9 0.1 1.6 1 1 0 1 1 1 1 ATP-binding dynein motor region D5 UPF0118 PF01594.11 ETO30888.1 - 9.1 5.1 7.0 3.6 6.4 2.7 1.7 1 1 1 2 2 2 0 Domain of unknown function DUF20 PT PF04886.7 ETO30889.1 - 5.2e-80 262.4 544.5 6.7e-05 22.1 11.6 24.0 2 1 14 16 16 16 12 PT repeat TSP_1 PF00090.14 ETO30889.1 - 0.00078 19.5 9.4 0.0017 18.4 6.6 1.6 1 0 0 1 1 1 1 Thrombospondin type 1 domain Pkinase PF00069.20 ETO30890.1 - 4.2e-25 88.3 7.0 1.3e-24 86.8 4.9 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO30890.1 - 8.8e-08 31.5 0.2 3.1e-07 29.7 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETO30890.1 - 0.0012 18.6 0.2 0.12 12.1 0.2 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 ETO30890.1 - 0.0044 16.6 4.3 0.0063 16.1 1.5 2.1 1 1 0 2 2 2 1 Choline/ethanolamine kinase NUFIP1 PF10453.4 ETO30891.1 - 8 6.0 9.1 0.86 9.1 0.4 2.7 3 0 0 3 3 3 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) ASF1_hist_chap PF04729.8 ETO30892.1 - 3.1e-57 192.5 0.2 3.7e-57 192.2 0.1 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone WD40 PF00400.27 ETO30893.1 - 3.6e-65 213.7 29.6 7.1e-12 44.7 0.5 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO30893.1 - 2.3e-10 39.2 6.8 0.0036 15.5 1.3 5.5 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO30893.1 - 2.1 7.0 13.8 17 4.0 5.0 3.8 2 2 0 3 3 3 0 Nup133 N terminal like zf-FCS PF06467.9 ETO30895.1 - 0.039 13.6 0.3 3.5 7.3 0.1 3.0 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif Corona_7 PF02398.11 ETO30895.1 - 0.094 13.2 2.2 0.2 12.1 0.2 2.2 2 0 0 2 2 2 0 Coronavirus protein 7 OST-HTH PF12872.2 ETO30896.1 - 0.0018 18.0 0.2 2.9 7.7 0.0 4.6 6 0 0 6 6 6 2 OST-HTH/LOTUS domain Gemini_AC4_5_2 PF08464.5 ETO30896.1 - 0.052 13.2 0.6 0.18 11.5 0.4 1.9 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region Aa_trans PF01490.13 ETO30897.1 - 1.7e-14 53.1 3.6 1.7e-14 53.1 2.5 1.6 1 1 1 2 2 2 1 Transmembrane amino acid transporter protein DUF4551 PF15087.1 ETO30898.1 - 6.2 5.0 10.8 7 4.8 7.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Srg PF02118.16 ETO30899.1 - 0.047 13.1 0.1 0.06 12.7 0.1 1.1 1 0 0 1 1 1 0 Srg family chemoreceptor WD40 PF00400.27 ETO30900.1 - 3.3e-81 264.5 36.2 3.5e-13 48.8 0.1 14.3 16 0 0 16 16 16 9 WD domain, G-beta repeat NACHT PF05729.7 ETO30900.1 - 4.7e-12 45.8 0.0 9.3e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.7 ETO30900.1 - 2.5e-07 30.1 19.4 0.19 11.4 0.0 8.8 9 0 0 9 9 9 1 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 ETO30900.1 - 8.9e-06 24.5 0.4 1.1 7.7 0.0 6.1 5 2 2 7 7 7 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region AAA_22 PF13401.1 ETO30900.1 - 1.8e-05 24.8 0.0 6.5e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain Pentapeptide PF00805.17 ETO30900.1 - 3.2e-05 23.0 0.8 6.7e-05 22.0 0.5 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO30900.1 - 0.00029 20.5 0.4 0.00095 18.9 0.1 2.0 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) AAA_18 PF13238.1 ETO30900.1 - 0.00053 20.3 0.3 0.008 16.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain Cytochrom_D1 PF02239.11 ETO30900.1 - 0.0018 16.6 3.4 0.13 10.5 0.0 4.7 5 2 1 6 6 6 1 Cytochrome D1 heme domain Pentapeptide_3 PF13576.1 ETO30900.1 - 0.0029 17.4 0.1 0.0073 16.1 0.1 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA_17 PF13207.1 ETO30900.1 - 0.017 15.9 0.0 0.089 13.6 0.0 2.3 2 0 0 2 2 1 0 AAA domain BSD PF03909.12 ETO30900.1 - 0.02 14.5 0.3 0.063 13.0 0.2 1.8 1 0 0 1 1 1 0 BSD domain AAA_16 PF13191.1 ETO30900.1 - 0.084 12.8 0.0 0.38 10.7 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 ETO30900.1 - 0.084 13.1 0.6 0.3 11.3 0.0 2.3 2 0 0 2 2 2 0 ABC transporter Phage_tail_2 PF06199.6 ETO30904.1 - 0.0023 17.9 2.8 0.0057 16.7 1.9 1.7 1 0 0 1 1 1 1 Phage major tail protein 2 Bul1_C PF04426.7 ETO30904.1 - 0.024 13.8 5.6 0.012 14.8 2.3 1.5 2 0 0 2 2 2 0 Bul1 C terminus Mucin PF01456.12 ETO30904.1 - 0.045 13.5 39.1 0.077 12.7 27.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein MGC-24 PF05283.6 ETO30904.1 - 0.086 12.6 18.4 0.15 11.8 12.8 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) gpUL132 PF11359.3 ETO30904.1 - 0.49 9.6 13.5 0.88 8.8 9.4 1.5 1 0 0 1 1 1 0 Glycoprotein UL132 DUF2057 PF09829.4 ETO30904.1 - 0.63 9.6 8.4 1.1 8.8 5.8 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) Med3 PF11593.3 ETO30904.1 - 2.2 7.4 18.2 3.2 6.9 12.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Med29 PF11568.3 ETO30905.1 - 0.012 15.7 4.2 0.023 14.7 2.9 1.5 1 0 0 1 1 1 0 Mediator complex subunit 29 DUF3595 PF12166.3 ETO30905.1 - 0.037 12.8 5.3 0.048 12.4 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) DUF2894 PF11445.3 ETO30905.1 - 0.085 13.1 1.7 0.13 12.4 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) DUF948 PF06103.6 ETO30905.1 - 0.23 11.3 2.5 2.8 7.8 0.0 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4298 PF14131.1 ETO30905.1 - 2 8.3 9.0 0.38 10.6 0.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4298) zf-RING_2 PF13639.1 ETO30906.1 - 2.2e-09 36.9 7.9 2.2e-09 36.9 5.5 2.7 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO30906.1 - 2.5e-08 33.7 9.4 2.5e-08 33.7 6.5 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 ETO30906.1 - 5.8e-08 32.4 6.9 5.8e-08 32.4 4.8 2.3 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 ETO30906.1 - 1.4e-07 31.0 7.6 1.4e-07 31.0 5.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO30906.1 - 1.6e-07 30.8 9.8 1.6e-07 30.8 6.8 2.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO30906.1 - 3.2e-06 26.7 7.9 3.2e-06 26.7 5.5 2.4 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 ETO30906.1 - 0.00018 21.1 1.6 0.00018 21.1 1.1 2.7 2 1 0 2 2 2 1 RING-type zinc-finger Baculo_IE-1 PF05290.6 ETO30906.1 - 0.0015 18.3 5.6 0.0032 17.1 3.9 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-rbx1 PF12678.2 ETO30906.1 - 0.0054 16.8 3.9 0.0054 16.8 2.7 2.7 2 2 0 2 2 2 1 RING-H2 zinc finger zf-RING_4 PF14570.1 ETO30906.1 - 0.51 9.9 5.9 2.1 7.9 4.1 2.0 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-MIZ PF02891.15 ETO30906.1 - 9.5 5.8 12.8 3.2 7.3 6.2 2.2 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger DUF4162 PF13732.1 ETO30907.1 - 0.0099 16.3 0.3 0.047 14.2 0.1 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4162) DUF4040 PF13244.1 ETO30908.1 - 3.9 7.5 8.6 0.2 11.6 1.3 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4040) RNA_pol_Rbc25 PF08292.7 ETO30910.1 - 1.4e-15 57.5 0.1 2.6e-15 56.7 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 Luteo_coat PF00894.13 ETO30910.1 - 0.00062 19.5 0.2 0.00093 18.9 0.1 1.2 1 0 0 1 1 1 1 Luteovirus coat protein SHS2_Rpb7-N PF03876.12 ETO30910.1 - 0.0078 16.3 0.2 0.036 14.1 0.1 2.1 1 1 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DUF3907 PF13047.1 ETO30910.1 - 0.1 12.2 0.1 0.2 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3907) tRNA-synt_1e PF01406.14 ETO30912.1 - 7.9e-45 153.2 2.2 1.5e-44 152.3 1.5 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1c PF00749.16 ETO30912.1 - 0.00081 18.1 0.5 0.002 16.8 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain CAP_GLY PF01302.20 ETO30915.1 - 0.012 15.2 0.0 0.044 13.4 0.0 1.9 2 0 0 2 2 2 0 CAP-Gly domain Afi1 PF07792.7 ETO30916.1 - 0.033 14.2 5.5 0.046 13.7 3.8 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Nucleoside_tran PF01733.13 ETO30916.1 - 0.058 12.5 1.6 0.063 12.4 1.1 1.0 1 0 0 1 1 1 0 Nucleoside transporter Folate_carrier PF01770.13 ETO30916.1 - 0.086 11.3 1.8 0.097 11.1 1.2 1.2 1 0 0 1 1 1 0 Reduced folate carrier OATP PF03137.15 ETO30916.1 - 2.7 5.9 5.8 3 5.7 4.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Raftlin PF15250.1 ETO30916.1 - 3.5 6.0 11.2 4.5 5.6 7.7 1.1 1 0 0 1 1 1 0 Raftlin MS_channel PF00924.13 ETO30917.1 - 0.0039 16.5 0.2 0.0062 15.8 0.1 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel Kelch_5 PF13854.1 ETO30917.1 - 0.011 15.6 1.5 12 5.9 0.1 3.4 3 0 0 3 3 3 0 Kelch motif Kelch_6 PF13964.1 ETO30917.1 - 0.061 13.5 7.3 2.3 8.5 0.2 3.7 3 1 1 4 4 4 0 Kelch motif Kelch_1 PF01344.20 ETO30917.1 - 0.1 12.1 10.3 1.7 8.2 1.3 3.9 3 1 0 3 3 3 0 Kelch motif Myb_DNA-bind_4 PF13837.1 ETO30918.1 - 0.0075 16.3 7.9 0.78 9.9 1.8 2.7 2 1 0 2 2 2 2 Myb/SANT-like DNA-binding domain DAP3 PF10236.4 ETO30918.1 - 0.012 14.5 0.4 0.019 13.8 0.3 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 EnY2 PF10163.4 ETO30918.1 - 0.1 12.5 7.4 0.16 11.8 0.3 3.2 2 1 1 3 3 3 0 Transcription factor e(y)2 Peptidase_U57 PF05582.7 ETO30918.1 - 2.6 6.9 5.8 0.41 9.5 1.1 1.7 1 1 1 2 2 2 0 YabG peptidase U57 DUF4047 PF13256.1 ETO30918.1 - 6.9 6.6 9.6 1.4 8.8 2.0 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4047) Choline_transpo PF04515.7 ETO30919.1 - 3.8e-69 232.9 31.3 3.8e-69 232.9 21.7 2.0 2 0 0 2 2 2 1 Plasma-membrane choline transporter DUF4328 PF14219.1 ETO30919.1 - 0.03 13.6 0.5 0.03 13.6 0.3 4.2 3 1 3 6 6 6 0 Domain of unknown function (DUF4328) NESP55 PF06390.7 ETO30920.1 - 0.17 11.2 5.6 0.21 10.9 3.9 1.1 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) WD40 PF00400.27 ETO30921.1 - 2.1e-79 258.8 10.8 4.3e-12 45.4 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO30921.1 - 3.4e-09 35.4 6.0 0.0051 15.0 0.0 6.0 1 1 4 6 6 6 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO30921.1 - 5e-06 26.1 0.3 0.0073 15.7 0.0 3.1 1 1 1 2 2 2 2 PQQ-like domain Cytochrom_D1 PF02239.11 ETO30921.1 - 2.6e-05 22.7 1.6 0.14 10.4 0.0 3.1 1 1 2 3 3 3 3 Cytochrome D1 heme domain PD40 PF07676.7 ETO30921.1 - 8.4e-05 22.1 6.5 2.3 8.0 0.1 5.3 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 ETO30921.1 - 0.00013 21.2 0.8 3.4 6.6 0.0 4.6 1 1 4 6 6 6 1 Protein of unknown function (DUF1258) Resistin PF06954.6 ETO30921.1 - 0.00062 19.9 0.0 43 4.4 0.0 4.4 2 2 2 4 4 4 0 Resistin Ricin_B_lectin PF00652.17 ETO30921.1 - 0.0023 17.9 0.2 0.044 13.7 0.0 2.8 2 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Nbas_N PF15492.1 ETO30921.1 - 0.02 14.0 0.4 1.1 8.2 0.1 3.2 1 1 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal MIP-T3 PF10243.4 ETO30922.1 - 2.1e-11 43.0 48.5 3.2e-11 42.4 33.6 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 LMBR1 PF04791.11 ETO30922.1 - 3.6e-07 29.1 0.0 1.2e-06 27.4 0.0 1.8 2 1 0 2 2 2 1 LMBR1-like membrane protein PB1 PF00564.19 ETO30923.1 - 2.3e-06 27.1 0.1 1.9e-05 24.2 0.0 2.3 1 1 0 1 1 1 1 PB1 domain OPT PF03169.10 ETO30923.1 - 0.027 12.8 0.0 0.031 12.7 0.0 1.2 1 0 0 1 1 1 0 OPT oligopeptide transporter protein DUF1640 PF07798.6 ETO30925.1 - 0.0018 18.3 7.6 0.0046 17.0 5.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) Mcp5_PH PF12814.2 ETO30925.1 - 0.0055 16.6 0.1 0.0055 16.6 0.0 2.4 3 0 0 3 3 3 1 Meiotic cell cortex C-terminal pleckstrin homology DUF2730 PF10805.3 ETO30925.1 - 0.0092 15.6 0.5 0.023 14.4 0.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2730) SKI PF01202.17 ETO30925.1 - 0.011 15.5 1.1 0.019 14.8 0.8 1.4 1 0 0 1 1 1 0 Shikimate kinase DUF4238 PF14022.1 ETO30925.1 - 0.027 13.7 0.5 0.042 13.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) Occludin_ELL PF07303.8 ETO30925.1 - 2.8 8.7 9.1 4.6 8.0 2.4 2.4 1 1 1 2 2 2 0 Occludin homology domain PT PF04886.7 ETO30926.1 - 2.3e-22 78.0 107.6 0.00015 21.0 8.1 6.0 2 1 1 3 3 3 2 PT repeat VWA_2 PF13519.1 ETO30926.1 - 0.0016 18.5 0.0 0.0022 18.1 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF605 PF04652.11 ETO30926.1 - 0.13 11.5 33.0 0.17 11.2 22.9 1.2 1 0 0 1 1 1 0 Vta1 like Gemini_C4 PF01492.12 ETO30926.1 - 0.3 10.8 0.1 0.3 10.8 0.1 3.2 2 1 0 2 2 2 0 Geminivirus C4 protein TFIIA PF03153.8 ETO30926.1 - 1.9 8.3 9.7 2.1 8.1 6.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SDF PF00375.13 ETO30927.1 - 2.6e-76 256.9 28.7 5.3e-72 242.7 13.3 2.6 1 1 0 2 2 2 2 Sodium:dicarboxylate symporter family CobT PF06213.7 ETO30927.1 - 4.4e-05 22.7 12.2 7.2e-05 22.0 8.4 1.3 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Ribosomal_60s PF00428.14 ETO30927.1 - 0.0028 18.0 3.7 0.0028 18.0 2.5 2.8 2 0 0 2 2 2 1 60s Acidic ribosomal protein Astro_capsid PF03115.9 ETO30927.1 - 0.066 11.4 5.4 0.094 10.9 3.7 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Glycoprotein_G PF00802.14 ETO30927.1 - 0.11 11.6 0.8 0.22 10.6 0.6 1.4 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G CDC45 PF02724.9 ETO30927.1 - 0.11 10.5 19.2 0.18 9.8 13.3 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 ETO30927.1 - 0.29 10.4 18.8 0.5 9.7 13.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Daxx PF03344.10 ETO30927.1 - 0.41 9.0 25.6 0.71 8.2 17.8 1.3 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 ETO30927.1 - 0.65 7.8 28.9 0.92 7.3 20.0 1.1 1 0 0 1 1 1 0 Nop14-like family IFT57 PF10498.4 ETO30927.1 - 2.1 7.0 10.7 3.4 6.3 7.4 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 BSP_II PF05432.6 ETO30927.1 - 2.2 7.5 28.3 3.8 6.7 19.6 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF2722 PF10846.3 ETO30927.1 - 3.3 6.6 16.7 5.5 5.9 11.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Hid1 PF12722.2 ETO30927.1 - 3.4 5.2 11.3 5 4.6 7.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PPP4R2 PF09184.6 ETO30927.1 - 6.3 6.2 22.7 12 5.3 15.7 1.4 1 0 0 1 1 1 0 PPP4R2 Pox_Ag35 PF03286.9 ETO30927.1 - 6.5 6.2 16.5 11 5.5 11.5 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein VID27 PF08553.5 ETO30927.1 - 7.6 4.6 17.5 11 4.1 12.1 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein AAA PF00004.24 ETO30928.1 - 1.8e-29 102.6 0.2 3.4e-29 101.7 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 ETO30928.1 - 0.00016 21.4 0.0 0.00032 20.5 0.0 1.5 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.9 ETO30928.1 - 0.049 13.5 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Bac_DnaA PF00308.13 ETO30928.1 - 0.12 12.0 0.1 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein PDZ PF00595.19 ETO30929.1 - 4.2e-08 33.2 0.0 1.3e-07 31.6 0.0 1.9 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) FYVE PF01363.16 ETO30929.1 - 8.1e-07 28.8 13.0 2e-06 27.5 9.0 1.6 1 0 0 1 1 1 1 FYVE zinc finger Baculo_IE-1 PF05290.6 ETO30929.1 - 0.0056 16.4 0.4 0.012 15.3 0.3 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) PDZ_2 PF13180.1 ETO30929.1 - 0.0089 15.8 0.0 0.033 14.0 0.0 1.9 1 0 0 1 1 1 1 PDZ domain DUF2951 PF11166.3 ETO30929.1 - 0.091 12.6 9.6 0.36 10.7 6.7 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) zinc-ribbons_6 PF07191.7 ETO30929.1 - 1 9.2 7.4 0.89 9.3 2.2 2.5 2 0 0 2 2 2 0 zinc-ribbons PhnA_Zn_Ribbon PF08274.7 ETO30929.1 - 1.7 8.4 4.4 80 3.1 0.0 3.4 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf-HIT PF04438.11 ETO30929.1 - 2 8.1 10.8 0.16 11.6 4.0 1.7 2 0 0 2 2 2 0 HIT zinc finger FAD_binding_6 PF00970.19 ETO30930.1 - 0.098 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain EF-hand_1 PF00036.27 ETO30931.1 - 0.001 18.1 0.4 0.0034 16.5 0.3 1.9 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 ETO30931.1 - 0.0017 17.6 0.1 0.005 16.1 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 ETO30931.1 - 0.0061 16.3 0.2 0.023 14.5 0.2 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 ETO30931.1 - 0.042 13.9 1.4 0.49 10.5 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain pair DUF1084 PF06454.6 ETO30933.1 - 0.02 13.9 0.1 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1084) TFIIS_C PF01096.13 ETO30934.1 - 0.079 12.6 0.1 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS) Ribosomal_L28e PF01778.12 ETO30935.1 - 1.7e-25 89.6 0.0 1.7e-25 89.6 0.0 4.1 3 1 1 4 4 4 1 Ribosomal L28e protein family Mak16 PF04874.9 ETO30935.1 - 2.7e-10 40.2 0.5 2.7e-10 40.2 0.3 4.1 2 2 2 4 4 4 2 Mak16 protein C-terminal region UPF0239 PF06783.6 ETO30936.1 - 0.041 13.8 0.0 0.096 12.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) 6PF2K PF01591.13 ETO30938.1 - 1.6e-49 168.0 1.0 4.3e-27 94.6 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 ETO30938.1 - 9.4e-30 103.7 0.0 1.8e-28 99.6 0.0 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 ETO30938.1 - 0.00045 21.0 0.1 0.0024 18.7 0.0 2.2 2 2 0 2 2 2 1 AAA domain AAA_33 PF13671.1 ETO30938.1 - 0.0012 18.7 0.0 0.0029 17.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 ETO30938.1 - 0.012 14.8 0.0 0.022 13.9 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 ETO30938.1 - 0.022 13.8 0.0 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Paf1 PF03985.8 ETO30940.1 - 3.6 6.2 17.4 4.6 5.8 12.1 1.3 1 0 0 1 1 1 0 Paf1 Hyccin PF09790.4 ETO30942.1 - 9.2e-08 31.2 1.5 0.0078 15.1 0.0 2.4 2 0 0 2 2 2 2 Hyccin Toxin_60 PF15607.1 ETO30943.1 - 0.15 12.0 1.7 0.21 11.6 1.2 1.4 1 1 0 1 1 1 0 Putative toxin 60 zf-CCHC PF00098.18 ETO30945.1 - 0.013 15.3 1.7 0.024 14.5 1.2 1.5 1 0 0 1 1 1 0 Zinc knuckle Seryl_tRNA_N PF02403.17 ETO30945.1 - 0.07 13.1 5.8 1.1 9.2 1.1 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 ETO30946.1 - 0.00024 20.7 0.6 0.0005 19.7 0.0 1.8 2 0 0 2 2 2 1 IncA protein CD34_antigen PF06365.7 ETO30946.1 - 0.0017 18.0 1.4 0.0042 16.7 0.0 2.1 2 0 0 2 2 2 1 CD34/Podocalyxin family Herpes_UL73 PF03554.8 ETO30946.1 - 0.007 16.1 1.0 0.016 14.9 0.7 1.7 1 0 0 1 1 1 1 UL73 viral envelope glycoprotein SID-1_RNA_chan PF13965.1 ETO30946.1 - 0.0078 14.4 0.0 0.015 13.5 0.0 1.4 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Adeno_E3_14_5 PF04834.7 ETO30946.1 - 0.0091 16.4 0.8 0.025 14.9 0.1 2.0 2 0 0 2 2 2 1 Early E3 14.5 kDa protein Neur_chan_memb PF02932.11 ETO30946.1 - 0.017 14.9 0.4 0.043 13.6 0.3 1.7 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Shisa PF13908.1 ETO30946.1 - 0.02 15.0 0.5 0.02 15.0 0.4 2.4 2 1 0 3 3 3 0 Wnt and FGF inhibitory regulator Herpes_gE PF02480.11 ETO30946.1 - 0.024 12.9 0.6 0.04 12.1 0.4 1.6 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E Hum_adeno_E3A PF05393.6 ETO30946.1 - 0.028 14.0 0.1 0.051 13.2 0.1 1.4 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein Plasmodium_Vir PF05795.6 ETO30946.1 - 0.39 9.8 2.8 2.3 7.3 0.0 2.1 1 1 1 2 2 2 0 Plasmodium vivax Vir protein Kei1 PF08552.6 ETO30946.1 - 0.72 9.4 5.9 2.8 7.5 4.1 2.0 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 TMEM154 PF15102.1 ETO30946.1 - 1.2 8.8 5.5 0.41 10.3 1.0 2.3 2 1 0 2 2 2 0 TMEM154 protein family SpoIIIAH PF12685.2 ETO30946.1 - 3.8 6.9 12.1 1.4e+02 1.8 8.4 2.3 1 1 0 1 1 1 0 SpoIIIAH-like protein RCR PF12273.3 ETO30946.1 - 4 7.9 10.2 0.17 12.4 0.3 2.8 1 1 1 2 2 1 0 Chitin synthesis regulation, resistance to Congo red DUF4448 PF14610.1 ETO30946.1 - 9.3 5.6 6.7 0.92 8.9 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) RXT2_N PF08595.6 ETO30947.1 - 0.032 14.0 7.2 0.092 12.5 1.8 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal PBP1_TM PF14812.1 ETO30947.1 - 0.039 14.2 9.9 1.5 9.1 2.9 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Hemocyanin_C PF03723.9 ETO30947.1 - 0.31 10.1 8.2 0.034 13.2 2.7 1.6 2 0 0 2 2 2 0 Hemocyanin, ig-like domain DUF4611 PF15387.1 ETO30947.1 - 0.4 10.8 8.3 3.5 7.8 2.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Prog_receptor PF02161.10 ETO30947.1 - 8 5.1 8.7 10 4.7 6.1 1.4 1 1 0 1 1 1 0 Progesterone receptor LAM_C PF12544.3 ETO30948.1 - 0.054 13.5 1.1 0.067 13.2 0.7 1.1 1 0 0 1 1 1 0 Lysine-2,3-aminomutase PEARLI-4 PF05278.7 ETO30948.1 - 0.25 10.6 2.8 0.3 10.4 1.9 1.0 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) MAPEG PF01124.13 ETO30949.1 - 0.22 11.1 0.9 0.55 9.8 0.0 2.1 2 0 0 2 2 2 0 MAPEG family LMBR1 PF04791.11 ETO30949.1 - 0.85 8.1 8.0 1 7.8 0.0 3.8 3 1 0 4 4 4 0 LMBR1-like membrane protein DUF2762 PF10960.3 ETO30950.1 - 0.092 12.4 0.3 5 6.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2762) Kinesin-related PF06548.6 ETO30950.1 - 0.15 10.5 1.0 0.21 10.1 0.7 1.1 1 0 0 1 1 1 0 Kinesin-related Fork_head PF00250.13 ETO30951.1 - 0.62 10.1 3.2 0.71 9.9 0.1 2.2 2 0 0 2 2 2 0 Fork head domain AAA PF00004.24 ETO30952.1 - 0.054 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Daxx PF03344.10 ETO30953.1 - 0.14 10.6 14.0 0.17 10.3 9.7 1.0 1 0 0 1 1 1 0 Daxx Family LAT PF15234.1 ETO30953.1 - 0.33 10.4 7.4 0.47 9.8 5.1 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells TRAP_alpha PF03896.11 ETO30953.1 - 1.1 8.1 7.4 1.7 7.5 5.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Ank_2 PF12796.2 ETO30954.1 - 5e-05 23.5 0.0 0.00041 20.6 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO30954.1 - 8.5e-05 22.4 0.0 0.0046 17.0 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.25 ETO30954.1 - 0.00016 21.2 0.0 0.0021 17.8 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 ETO30954.1 - 0.0076 16.7 0.1 0.034 14.6 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO30954.1 - 0.031 14.5 0.1 0.71 10.2 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeats (many copies) HEAT_2 PF13646.1 ETO30955.1 - 1.9e-12 47.3 0.0 9.3e-06 25.8 0.0 5.1 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.17 ETO30955.1 - 3.7e-09 35.8 0.1 0.34 11.0 0.0 8.3 9 1 0 9 9 9 1 HEAT repeat HEAT_EZ PF13513.1 ETO30955.1 - 4e-07 30.3 0.1 3.5 8.2 0.0 7.1 7 1 1 8 8 8 2 HEAT-like repeat Condensin2nSMC PF12422.3 ETO30955.1 - 0.014 15.1 17.2 0.015 15.0 3.0 4.3 3 2 3 6 6 6 0 Condensin II non structural maintenance of chromosomes subunit HEAT_PBS PF03130.11 ETO30955.1 - 0.036 14.5 0.1 2.2 8.9 0.0 4.0 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Mitofilin PF09731.4 ETO30956.1 - 4.9 5.6 16.4 6.9 5.1 11.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein zf-C3HC4_2 PF13923.1 ETO30957.1 - 0.092 12.7 4.8 0.84 9.7 3.3 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ATG16 PF08614.6 ETO30957.1 - 1.7 8.4 8.9 8.3 6.1 3.1 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4549 PF15082.1 ETO30958.1 - 0.36 10.4 4.4 0.51 9.9 1.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4549) TnpV PF14198.1 ETO30958.1 - 0.5 10.2 6.1 0.16 11.8 2.3 1.6 2 0 0 2 2 2 0 Transposon-encoded protein TnpV McyA_C PF12593.3 ETO30959.1 - 0.61 9.8 4.5 0.4 10.4 1.6 1.8 2 0 0 2 2 2 0 Microcystin synthetase C terminal PT PF04886.7 ETO30961.1 - 6.7e-44 146.9 168.3 3.4e+03 -2.6 1.6 7.4 2 1 0 2 2 2 0 PT repeat SKG6 PF08693.5 ETO30961.1 - 0.0076 15.5 1.0 0.028 13.7 0.7 2.0 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF912 PF06024.7 ETO30961.1 - 0.058 13.4 0.0 0.058 13.4 0.0 4.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2562 PF10814.3 ETO30961.1 - 0.079 12.9 0.2 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2562) Glycoprotein_G PF00802.14 ETO30961.1 - 4.3 6.4 74.4 0.027 13.6 16.2 3.7 1 1 2 3 3 3 0 Pneumovirus attachment glycoprotein G TACC PF05010.9 ETO30963.1 - 0.059 13.1 0.7 0.08 12.7 0.5 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) Pkinase PF00069.20 ETO30964.1 - 6.6e-39 133.6 2.4 1.5e-26 93.1 0.1 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 ETO30964.1 - 1.9e-19 69.7 1.9 5.9e-13 48.4 0.5 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase 3HCDH_N PF02737.13 ETO30968.1 - 2.6e-48 164.0 6.5 2.9e-28 98.7 0.3 2.2 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 ETO30968.1 - 3.3e-35 120.3 0.0 7e-35 119.3 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Pyr_redox_3 PF13738.1 ETO30968.1 - 0.0041 17.1 0.4 0.0065 16.5 0.3 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.10 ETO30968.1 - 0.011 15.5 1.2 0.035 13.9 0.1 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 ETO30968.1 - 0.013 15.8 4.3 0.014 15.7 1.5 2.2 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.19 ETO30968.1 - 0.016 14.1 0.3 0.047 12.5 0.2 1.7 1 1 1 2 2 2 0 FAD dependent oxidoreductase MTS PF05175.9 ETO30968.1 - 0.048 13.0 0.1 0.1 11.9 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase small domain TrkA_N PF02254.13 ETO30968.1 - 0.085 12.8 0.5 0.23 11.4 0.3 1.8 1 1 0 1 1 1 0 TrkA-N domain Lipoprotein_17 PF04200.7 ETO30968.1 - 0.1 12.7 0.2 0.1 12.7 0.2 2.4 2 0 0 2 2 2 0 Lipoprotein associated domain Pkinase PF00069.20 ETO30969.1 - 3.2e-14 52.7 0.1 1.1e-13 51.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO30969.1 - 0.0049 15.9 0.6 0.0074 15.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_C PF00433.19 ETO30969.1 - 0.0063 17.0 0.0 0.014 15.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain PepSY_TM_2 PF13703.1 ETO30971.1 - 0.58 10.3 7.8 1 9.5 0.2 3.4 2 1 1 3 3 3 0 PepSY-associated TM helix Pkinase PF00069.20 ETO30972.1 - 4.1e-54 183.4 1.0 2.4e-34 118.6 0.3 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO30972.1 - 1.7e-26 92.8 1.0 1.3e-19 70.2 0.4 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 ETO30972.1 - 0.00021 20.3 1.5 0.0093 14.9 0.0 2.6 2 1 1 3 3 3 1 Kinase-like Kdo PF06293.9 ETO30972.1 - 0.00023 20.2 0.0 0.00048 19.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO30972.1 - 0.027 14.2 0.0 0.064 12.9 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_C PF00433.19 ETO30972.1 - 0.36 11.3 2.4 1.5 9.3 1.6 2.1 1 1 0 1 1 1 0 Protein kinase C terminal domain XPC-binding PF09280.6 ETO30973.1 - 1.3e-09 37.3 17.6 1.3e-09 37.3 12.2 2.6 2 1 0 2 2 2 1 XPC-binding domain UBA PF00627.26 ETO30973.1 - 0.0052 16.5 0.3 0.0052 16.5 0.2 2.3 2 0 0 2 2 2 1 UBA/TS-N domain EF-hand_7 PF13499.1 ETO30975.1 - 3.1e-08 33.6 1.5 0.01 15.9 0.2 3.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO30975.1 - 0.00021 20.9 1.3 0.36 10.8 0.0 4.2 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.27 ETO30975.1 - 0.0088 15.2 0.1 1.2 8.6 0.0 3.5 4 0 0 4 4 4 1 EF hand EF-hand_5 PF13202.1 ETO30975.1 - 0.11 11.9 0.0 1 8.7 0.0 2.5 2 0 0 2 2 2 0 EF hand PH PF00169.24 ETO30976.1 - 3.5e-07 30.3 0.1 8.2e-07 29.1 0.1 1.7 1 0 0 1 1 1 1 PH domain ArsC PF03960.10 ETO30976.1 - 0.048 13.7 0.6 0.19 11.8 0.3 1.9 2 0 0 2 2 2 0 ArsC family WD40 PF00400.27 ETO30977.1 - 0.0023 17.7 3.2 0.92 9.4 0.2 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat WD40 PF00400.27 ETO30978.1 - 0.042 13.7 0.2 1.3 9.0 0.0 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat KOW PF00467.24 ETO30980.1 - 2.9e-12 45.7 25.6 0.00016 21.2 0.1 7.5 7 0 0 7 7 7 6 KOW motif Ras PF00071.17 ETO30981.1 - 1e-05 24.9 0.0 1.3e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO30981.1 - 0.00013 22.3 0.1 0.00017 22.0 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 ETO30981.1 - 0.0048 16.8 0.0 0.0058 16.5 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase malic PF00390.14 ETO30981.1 - 0.063 12.8 0.0 0.075 12.6 0.0 1.2 1 0 0 1 1 1 0 Malic enzyme, N-terminal domain Ribosomal_S13 PF00416.17 ETO30982.1 - 3.8e-09 36.9 0.6 9.2e-09 35.7 0.1 1.9 1 1 1 2 2 2 1 Ribosomal protein S13/S18 EAP30 PF04157.11 ETO30982.1 - 0.0096 15.1 0.2 0.015 14.4 0.1 1.3 1 0 0 1 1 1 1 EAP30/Vps36 family Ribosomal_L6e PF01159.14 ETO30982.1 - 0.56 10.4 3.0 0.76 10.0 1.2 1.7 1 1 0 1 1 1 0 Ribosomal protein L6e EF-hand_7 PF13499.1 ETO30983.1 - 2.1e-08 34.1 1.2 0.0015 18.6 0.1 3.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 ETO30983.1 - 4.4e-06 25.5 2.4 0.0065 15.6 0.0 3.9 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 ETO30983.1 - 3e-05 23.5 2.4 0.06 13.2 0.1 3.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 ETO30983.1 - 0.00021 20.8 0.9 0.0057 16.2 0.1 3.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 ETO30983.1 - 0.0025 17.0 0.8 0.014 14.6 0.1 2.5 2 0 0 2 2 2 1 EF hand NOA36 PF06524.7 ETO30983.1 - 2.8 7.1 16.7 0.11 11.6 7.1 2.0 2 0 0 2 2 2 0 NOA36 protein DUF869 PF05911.6 ETO30986.1 - 2.5 6.2 61.4 0.073 11.3 36.7 2.2 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) Cauli_AT PF03233.8 ETO30987.1 - 0.11 12.2 8.2 0.11 12.1 5.7 1.1 1 0 0 1 1 1 0 Aphid transmission protein YgbB PF02542.11 ETO30987.1 - 0.11 12.2 2.1 0.13 12.1 1.4 1.1 1 0 0 1 1 1 0 YgbB family KilA-N PF04383.8 ETO30987.1 - 0.92 9.1 6.9 1.1 8.9 4.6 1.3 1 1 0 1 1 1 0 KilA-N domain PUB PF09409.5 ETO30988.1 - 1.4e-14 53.6 0.3 3e-14 52.5 0.2 1.6 1 0 0 1 1 1 1 PUB domain CAP PF00188.21 ETO30988.1 - 6.6e-14 52.4 1.7 9.6e-13 48.7 0.0 2.7 2 0 0 2 2 2 1 Cysteine-rich secretory protein family DUF3595 PF12166.3 ETO30988.1 - 0.22 10.3 7.9 0.44 9.3 5.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) Dala_Dala_lig_N PF01820.16 ETO30988.1 - 0.55 10.5 5.0 0.96 9.7 1.0 2.7 1 1 0 2 2 2 0 D-ala D-ala ligase N-terminus Secretin_N_2 PF07655.8 ETO30988.1 - 7.1 7.0 21.2 0.38 11.1 10.3 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain DSPc PF00782.15 ETO30989.1 - 2.3e-24 85.4 0.5 3.5e-24 84.8 0.3 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 ETO30989.1 - 0.00096 18.5 1.2 0.0069 15.7 0.1 2.2 2 1 0 2 2 2 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 ETO30989.1 - 0.013 14.4 0.3 0.015 14.1 0.2 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase TAP_C PF03943.8 ETO30989.1 - 0.028 13.8 0.0 0.065 12.6 0.0 1.6 1 0 0 1 1 1 0 TAP C-terminal domain UBA_4 PF14555.1 ETO30989.1 - 0.039 13.4 0.0 0.08 12.4 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain DSPn PF14671.1 ETO30989.1 - 0.068 13.1 0.9 0.15 12.0 0.5 1.7 1 1 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half WD40 PF00400.27 ETO30990.1 - 3.7e-67 219.9 21.9 3.3e-12 45.7 0.2 7.2 6 1 1 7 7 7 7 WD domain, G-beta repeat Resistin PF06954.6 ETO30990.1 - 0.11 12.8 5.5 20 5.5 0.1 4.4 2 1 3 5 5 5 0 Resistin PD40 PF07676.7 ETO30990.1 - 0.69 9.6 6.9 4.6 7.0 0.0 4.1 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 ETO30991.1 - 2.3e-67 220.6 14.5 5.2e-11 41.9 0.0 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO30991.1 - 1.2e-08 34.7 1.9 0.01 16.0 0.0 4.4 2 2 1 3 3 3 2 Kelch motif Gmad1 PF10647.4 ETO30991.1 - 7.2e-06 25.5 0.1 0.0049 16.2 0.0 3.2 2 1 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain Nucleoporin_N PF08801.6 ETO30991.1 - 3.1e-05 22.9 7.3 0.15 10.8 2.4 5.1 2 1 2 4 4 4 1 Nup133 N terminal like PD40 PF07676.7 ETO30991.1 - 4.2e-05 23.1 9.6 6.6 6.5 0.1 6.2 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 ETO30991.1 - 9.2e-05 21.6 2.4 0.36 9.8 0.0 3.9 1 1 3 5 5 5 2 Neuroblastoma-amplified sequence, N terminal Kelch_2 PF07646.10 ETO30991.1 - 0.0001 21.9 0.5 0.24 11.2 0.1 4.1 3 0 0 3 3 3 1 Kelch motif PQQ_2 PF13360.1 ETO30991.1 - 0.0021 17.5 1.4 0.098 12.1 0.1 2.6 1 1 1 2 2 2 2 PQQ-like domain Kelch_5 PF13854.1 ETO30991.1 - 0.0039 17.1 1.5 0.55 10.2 0.0 3.6 3 0 0 3 3 3 1 Kelch motif Ricin_B_lectin PF00652.17 ETO30991.1 - 0.0052 16.8 2.5 0.14 12.2 0.1 3.3 1 1 2 3 3 3 1 Ricin-type beta-trefoil lectin domain Kelch_1 PF01344.20 ETO30991.1 - 0.0075 15.7 7.0 0.047 13.2 0.4 3.7 4 0 0 4 4 4 1 Kelch motif Clathrin_propel PF01394.15 ETO30991.1 - 0.033 14.4 1.9 18 5.8 0.0 4.6 5 0 0 5 5 5 0 Clathrin propeller repeat Proteasome_A_N PF10584.4 ETO30991.1 - 3.3 7.1 9.0 88 2.5 0.0 5.3 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 ETO30992.1 - 1e-70 231.2 21.6 6.3e-15 54.3 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO30992.1 - 3.1e-06 25.7 2.1 0.018 13.3 0.0 3.4 1 1 1 3 3 3 3 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO30992.1 - 1.8e-05 23.6 13.1 0.14 10.8 2.5 4.5 1 1 1 3 3 3 2 Nup133 N terminal like Resistin PF06954.6 ETO30992.1 - 0.00026 21.1 2.0 2 8.7 0.1 3.8 2 2 2 4 4 4 2 Resistin Mid2 PF04478.7 ETO30992.1 - 0.00073 18.9 2.4 2.3 7.6 0.0 4.1 2 2 3 5 5 5 2 Mid2 like cell wall stress sensor PD40 PF07676.7 ETO30992.1 - 0.039 13.6 0.8 25 4.6 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Innate_immun PF12782.2 ETO30993.1 - 1.7 7.8 15.5 0.038 13.2 4.9 2.0 2 0 0 2 2 2 0 Invertebrate innate immunity transcript family DUF4578 PF15147.1 ETO30993.1 - 2.7 8.3 11.4 5.6 7.3 7.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4578) LMBR1 PF04791.11 ETO30995.1 - 2.8e-17 62.4 17.0 1.3e-15 56.9 11.8 2.4 1 1 0 1 1 1 1 LMBR1-like membrane protein DUF3671 PF12420.3 ETO30995.1 - 0.13 12.2 0.0 0.13 12.2 0.0 5.4 2 2 3 5 5 5 0 Protein of unknown function OAD_gamma PF04277.8 ETO30995.1 - 1 9.7 0.0 1 9.7 0.0 4.9 5 1 1 6 6 6 0 Oxaloacetate decarboxylase, gamma chain Rep_fac_C PF08542.6 ETO30996.1 - 8.1e-10 38.5 0.0 2.5e-09 36.9 0.0 1.7 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 ETO30996.1 - 5.8e-07 29.3 0.0 9.6e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNA_pol3_delta PF06144.8 ETO30996.1 - 0.00024 20.6 0.0 0.00033 20.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Sigma54_activ_2 PF14532.1 ETO30996.1 - 0.0027 17.7 0.1 0.0054 16.7 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.24 ETO30996.1 - 0.042 14.0 0.0 0.19 11.9 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Shikimate_DH PF01488.15 ETO30997.1 - 0.0042 17.1 0.3 0.0057 16.7 0.2 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase MGDG_synth PF06925.6 ETO30997.1 - 0.059 13.2 2.7 0.076 12.9 0.2 2.0 1 1 0 2 2 2 0 Monogalactosyldiacylglycerol (MGDG) synthase DUF1548 PF07579.6 ETO30997.1 - 0.13 12.4 5.4 0.031 14.3 1.4 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1548) FlgD PF03963.9 ETO30998.1 - 0.005 16.8 0.3 0.02 14.9 0.0 1.9 2 0 0 2 2 2 1 Flagellar hook capping protein - N-terminal region RGS PF00615.14 ETO30998.1 - 0.0066 16.5 1.6 0.0066 16.5 1.1 1.8 1 1 1 2 2 2 1 Regulator of G protein signaling domain MCLC PF05934.6 ETO30998.1 - 0.064 11.5 2.8 0.031 12.5 0.4 1.6 2 0 0 2 2 2 0 Mid-1-related chloride channel (MCLC) RNA_pol_Rpb4 PF03874.11 ETO30998.1 - 0.19 11.7 5.2 0.1 12.6 1.2 2.0 1 1 1 2 2 2 0 RNA polymerase Rpb4 TPR_11 PF13414.1 ETO31000.1 - 6e-10 38.6 24.0 2.2e-06 27.1 8.5 2.9 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 ETO31000.1 - 1.1e-09 37.4 10.5 0.00029 20.5 0.5 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO31000.1 - 4.4e-08 32.4 16.2 0.00016 21.1 0.4 3.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO31000.1 - 7.3e-08 32.6 6.0 8.7e-07 29.1 0.4 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO31000.1 - 8.8e-08 31.7 18.3 0.00029 20.7 0.4 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO31000.1 - 2e-07 30.9 0.7 0.0044 17.5 0.3 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO31000.1 - 1.7e-06 28.0 8.8 3e-06 27.2 6.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 ETO31000.1 - 3.2e-06 26.5 9.4 0.4 10.5 0.7 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO31000.1 - 7.9e-06 25.9 8.0 0.086 13.3 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO31000.1 - 1.7e-05 24.6 14.3 0.005 16.7 4.4 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO31000.1 - 3.4e-05 24.3 2.0 0.0062 17.1 1.6 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETO31000.1 - 0.0003 20.5 0.9 0.0095 15.7 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.1 ETO31000.1 - 0.029 13.4 3.9 0.55 9.2 2.7 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETO31000.1 - 0.21 11.4 5.5 30 4.7 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat SR-25 PF10500.4 ETO31000.1 - 3.7 6.9 11.5 0.14 11.5 3.2 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TPR_10 PF13374.1 ETO31000.1 - 5.4 7.0 8.2 26 4.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat RNA_pol_Rpb5_C PF01191.14 ETO31001.1 - 0.12 12.0 0.1 0.19 11.3 0.0 1.5 1 1 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain DUF4557 PF15101.1 ETO31001.1 - 0.49 10.1 3.9 0.56 10.0 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DNAJ_related PF12339.3 ETO31001.1 - 0.66 9.8 5.0 1.5 8.7 2.6 1.9 2 0 0 2 2 2 0 DNA-J related protein TMPIT PF07851.8 ETO31001.1 - 1.2 8.0 4.3 1.3 7.9 3.0 1.0 1 0 0 1 1 1 0 TMPIT-like protein Med15 PF09606.5 ETO31001.1 - 2.1 6.4 14.9 2.2 6.3 10.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4171 PF13775.1 ETO31003.1 - 0.38 10.9 4.3 0.095 12.8 0.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4171) Menin PF05053.8 ETO31003.1 - 1.1 7.3 11.2 0.039 12.1 3.8 1.4 2 0 0 2 2 2 0 Menin Serinc PF03348.10 ETO31004.1 - 0.045 12.4 0.0 0.05 12.3 0.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2431 PF10354.4 ETO31005.1 - 3.2e-24 85.7 0.0 3.9e-19 69.2 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF2431) HSP90 PF00183.13 ETO31006.1 - 0.017 13.5 8.9 0.02 13.3 6.2 1.1 1 0 0 1 1 1 0 Hsp90 protein DUF908 PF06012.7 ETO31006.1 - 0.034 13.4 3.2 0.033 13.5 2.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Sporozoite_P67 PF05642.6 ETO31006.1 - 0.048 11.5 7.5 0.055 11.3 5.2 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Tim54 PF11711.3 ETO31006.1 - 0.066 11.8 7.4 0.092 11.3 5.2 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RR_TM4-6 PF06459.7 ETO31006.1 - 0.091 12.6 14.5 0.1 12.4 10.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4175 PF13779.1 ETO31006.1 - 0.2 9.3 10.7 0.22 9.2 7.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SURF2 PF05477.6 ETO31006.1 - 0.29 10.2 14.3 0.34 9.9 9.9 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CDC45 PF02724.9 ETO31006.1 - 0.39 8.6 10.2 0.47 8.4 7.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 ETO31006.1 - 0.47 9.7 17.2 0.65 9.3 11.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) GAGA_bind PF06217.7 ETO31006.1 - 0.77 9.6 10.8 1 9.2 7.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RP-C_C PF11800.3 ETO31006.1 - 0.91 9.1 6.0 1.2 8.7 4.2 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Neur_chan_memb PF02932.11 ETO31006.1 - 0.95 9.2 6.3 1.3 8.9 4.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region YABBY PF04690.8 ETO31006.1 - 1.4 9.1 4.0 2 8.6 2.8 1.2 1 0 0 1 1 1 0 YABBY protein Spore_coat_CotO PF14153.1 ETO31006.1 - 1.6 8.1 18.0 0.094 12.1 9.1 1.4 2 0 0 2 2 1 0 Spore coat protein CotO Hid1 PF12722.2 ETO31006.1 - 1.8 6.1 6.5 1.7 6.2 4.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAM176 PF14851.1 ETO31006.1 - 1.8 8.2 5.0 3.3 7.3 3.5 1.5 1 0 0 1 1 1 0 FAM176 family DUF2201_N PF13203.1 ETO31006.1 - 3.6 6.6 7.6 4.9 6.2 5.2 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain DDHD PF02862.12 ETO31006.1 - 4 7.1 7.9 4.5 7.0 5.5 1.3 1 0 0 1 1 1 0 DDHD domain TP53IP5 PF15331.1 ETO31006.1 - 4.1 7.2 10.6 7 6.4 7.3 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 CobT PF06213.7 ETO31006.1 - 5 6.1 17.7 7.2 5.6 12.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NPR3 PF03666.8 ETO31006.1 - 5.2 5.4 9.9 7.2 5.0 6.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 POX PF07526.6 ETO31006.1 - 5.4 7.2 9.7 8.9 6.5 6.7 1.4 1 0 0 1 1 1 0 Associated with HOX Borrelia_P83 PF05262.6 ETO31006.1 - 5.5 5.1 13.8 5.7 5.0 9.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Paramyxo_ncap PF00973.14 ETO31006.1 - 6.1 5.4 5.9 7.4 5.1 4.1 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Vfa1 PF08432.5 ETO31006.1 - 6.1 6.8 19.6 0.35 10.8 10.0 1.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF4637 PF15470.1 ETO31006.1 - 6.2 6.4 8.7 9.2 5.8 6.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) STT3 PF02516.9 ETO31007.1 - 1.5e-05 24.1 0.0 2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit OATP PF03137.15 ETO31007.1 - 0.0016 16.5 0.9 0.0024 15.9 0.6 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family FPN1 PF06963.7 ETO31007.1 - 0.018 13.4 0.2 0.028 12.7 0.1 1.3 1 0 0 1 1 1 0 Ferroportin1 (FPN1) OAD_gamma PF04277.8 ETO31007.1 - 0.032 14.5 1.3 0.069 13.5 0.9 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Ofd1_CTDD PF10637.4 ETO31007.1 - 0.057 12.5 5.7 0.061 12.4 3.5 1.3 1 1 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term Bap31 PF05529.7 ETO31007.1 - 0.082 12.3 3.4 0.21 11.0 2.4 1.6 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like FHIPEP PF00771.15 ETO31007.1 - 0.094 11.0 0.2 0.11 10.7 0.1 1.1 1 0 0 1 1 1 0 FHIPEP family Mem_trans PF03547.13 ETO31007.1 - 0.19 10.0 3.5 0.33 9.2 2.4 1.5 1 1 0 1 1 1 0 Membrane transport protein DUF788 PF05620.6 ETO31007.1 - 1.2 8.9 10.6 0.49 10.2 4.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF788) PIG-P PF08510.7 ETO31007.1 - 2.6 7.7 7.7 14 5.2 5.3 2.2 1 1 0 1 1 1 0 PIG-P PCI PF01399.22 ETO31009.1 - 7.1e-15 55.2 0.5 1.6e-14 54.1 0.1 1.8 2 0 0 2 2 2 1 PCI domain Secretin_N_2 PF07655.8 ETO31010.1 - 0.2 12.0 29.7 0.79 10.1 0.9 2.8 2 0 0 2 2 2 0 Secretin N-terminal domain FimP PF09766.4 ETO31010.1 - 1.3 8.0 25.9 0.032 13.3 2.6 2.2 2 0 0 2 2 2 0 Fms-interacting protein IlvC PF01450.14 ETO31011.1 - 0.061 13.2 3.1 0.067 13.1 1.6 1.4 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Packaging_FI PF14000.1 ETO31011.1 - 0.48 10.6 3.5 0.33 11.1 0.8 1.8 1 1 1 2 2 2 0 DNA packaging protein FI Rootletin PF15035.1 ETO31013.1 - 0.0014 18.5 15.0 0.0014 18.5 10.4 8.0 2 1 5 7 7 7 3 Ciliary rootlet component, centrosome cohesion Metallophos PF00149.23 ETO31014.1 - 0.002 17.5 0.1 0.0034 16.8 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CENP-M PF11111.3 ETO31014.1 - 0.03 13.5 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 Centromere protein M (CENP-M) DUF2633 PF11119.3 ETO31014.1 - 0.066 12.9 1.1 0.14 11.9 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2633) FYRC PF05965.9 ETO31015.1 - 1.2e-20 73.0 0.0 2.2e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.9 ETO31015.1 - 4.5e-12 45.2 0.1 8.2e-12 44.3 0.1 1.4 1 0 0 1 1 1 1 F/Y-rich N-terminus Chromo PF00385.19 ETO31016.1 - 0.0045 16.6 0.9 0.012 15.2 0.6 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF111 PF01969.12 ETO31016.1 - 0.091 11.5 1.5 0.14 10.9 0.6 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF111 YlqD PF11068.3 ETO31016.1 - 0.64 10.0 10.5 1.1 9.3 1.2 4.0 3 2 2 5 5 5 0 YlqD protein Bromodomain PF00439.20 ETO31017.1 - 0.00037 20.3 1.7 0.00045 20.0 0.1 2.0 2 0 0 2 2 2 1 Bromodomain SDA1 PF05285.7 ETO31017.1 - 0.004 16.5 25.7 0.0074 15.6 17.8 1.6 1 0 0 1 1 1 1 SDA1 Daxx PF03344.10 ETO31017.1 - 0.076 11.4 44.2 0.033 12.6 29.0 1.5 1 1 1 2 2 2 0 Daxx Family Sigma70_ner PF04546.8 ETO31017.1 - 2.1 7.8 21.6 5.9 6.4 15.0 1.9 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 ETO31017.1 - 7.8 4.3 28.1 13 3.6 19.5 1.3 1 0 0 1 1 1 0 CDC45-like protein Bromodomain PF00439.20 ETO31018.1 - 1.5e-12 47.2 0.1 4.3e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Bromodomain zf-B_box PF00643.19 ETO31019.1 - 6.5e-06 25.9 8.3 6.5e-06 25.9 5.8 2.6 2 1 1 3 3 3 1 B-box zinc finger Bromodomain PF00439.20 ETO31019.1 - 1.8e-05 24.5 0.1 4e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 Bromodomain zf-RING_5 PF14634.1 ETO31019.1 - 0.36 10.6 18.1 0.069 12.8 3.5 2.8 2 1 1 3 3 3 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 ETO31019.1 - 0.98 9.4 13.9 3.9 7.5 6.4 3.2 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 ETO31019.1 - 1 9.1 11.5 0.11 12.3 3.8 2.0 1 1 1 2 2 2 0 Zinc-binding RING-finger RecR PF02132.10 ETO31019.1 - 2.4 7.6 16.9 0.089 12.2 2.5 3.3 1 1 1 2 2 2 0 RecR protein Ribosomal_S27e PF01667.12 ETO31019.1 - 7.8 6.1 10.9 2.8 7.5 1.9 2.7 2 0 0 2 2 2 0 Ribosomal protein S27 NIF PF03031.13 ETO31020.1 - 6.2e-42 142.9 0.2 6.2e-42 142.9 0.1 1.7 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase ATP_bind_3 PF01171.15 ETO31020.1 - 0.074 12.5 1.4 0.14 11.5 1.0 1.4 1 0 0 1 1 1 0 PP-loop family Cpn60_TCP1 PF00118.19 ETO31021.1 - 1.6e-23 83.1 0.2 3.6e-23 81.9 0.1 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.19 ETO31022.1 - 1.1e-19 70.5 0.0 1.2e-19 70.3 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ank PF00023.25 ETO31023.1 - 6.4e-10 38.3 0.3 1.8e-06 27.4 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 ETO31023.1 - 1.2e-09 38.3 0.3 1.2e-08 35.1 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO31023.1 - 2.9e-07 30.5 0.1 8.6e-07 29.0 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO31023.1 - 3.2e-07 29.9 0.3 0.0024 17.9 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat WD40 PF00400.27 ETO31023.1 - 2.4e-05 24.0 9.5 0.58 10.1 0.0 4.9 4 1 0 4 4 4 2 WD domain, G-beta repeat Ank_4 PF13637.1 ETO31023.1 - 0.00013 22.3 0.1 0.00043 20.7 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF948 PF06103.6 ETO31023.1 - 4.1 7.3 6.5 0.4 10.5 0.2 2.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF3507 PF12015.3 ETO31024.1 - 0.0055 16.2 1.2 0.01 15.3 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) TLD PF07534.11 ETO31027.1 - 7.6e-14 51.8 2.0 7.6e-14 51.8 1.4 1.8 2 1 0 2 2 2 1 TLD Phage_tail_2 PF06199.6 ETO31027.1 - 0.17 11.9 2.0 7.2 6.6 0.0 2.2 2 0 0 2 2 2 0 Phage major tail protein 2 SOBP PF15279.1 ETO31029.1 - 0.48 10.7 10.3 0.17 12.2 5.1 1.5 1 1 1 2 2 2 0 Sine oculis-binding protein PRP1_N PF06424.7 ETO31029.1 - 0.6 10.4 7.1 1.2 9.4 4.8 1.8 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal zf-C2H2_jaz PF12171.3 ETO31030.1 - 1.5e-05 24.9 13.2 0.004 17.2 0.1 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 ETO31030.1 - 5.8e-05 23.1 11.6 0.034 14.3 0.2 3.8 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 ETO31030.1 - 8.5e-05 22.6 30.4 0.00058 20.0 0.5 5.3 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETO31030.1 - 0.0016 18.6 30.9 0.0049 17.1 0.4 5.4 5 0 0 5 5 5 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETO31030.1 - 0.0016 18.6 1.2 0.0016 18.6 0.8 5.2 5 0 0 5 5 5 2 Zinc-finger double domain DUF3605 PF12239.3 ETO31032.1 - 1.8e-17 63.6 3.7 2.4e-17 63.2 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Apo-CIII PF05778.7 ETO31033.1 - 0.095 12.0 0.0 0.28 10.5 0.0 1.8 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) Pyr_redox_3 PF13738.1 ETO31036.1 - 0.2 11.6 1.6 0.26 11.3 0.7 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.20 ETO31037.1 - 1.5e-77 260.2 0.1 4.2e-77 258.7 0.1 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO31037.1 - 2.5e-46 157.8 0.0 4.5e-46 157.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO31037.1 - 3.1e-09 36.1 0.2 1.6e-08 33.8 0.0 2.1 2 1 1 3 3 3 1 Kinase-like Kdo PF06293.9 ETO31037.1 - 0.0011 18.0 0.1 0.0021 17.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO31037.1 - 0.0064 16.2 0.4 0.1 12.2 0.3 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family VanZ PF04892.7 ETO31038.1 - 0.55 10.1 3.6 4 7.3 1.2 2.3 2 0 0 2 2 2 0 VanZ like family EF-hand_1 PF00036.27 ETO31040.1 - 5.4e-13 47.2 2.0 2.4e-07 29.5 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 ETO31040.1 - 1.1e-11 44.6 3.1 1.5e-05 25.0 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO31040.1 - 4.2e-11 41.7 1.8 1.5e-05 24.4 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 ETO31040.1 - 9.6e-11 40.5 3.3 1.9e-05 23.7 0.3 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 ETO31040.1 - 3.1e-08 33.1 1.2 7.3e-05 22.3 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_10 PF14788.1 ETO31040.1 - 0.0026 17.3 2.4 1.7 8.3 0.1 2.8 2 0 0 2 2 2 2 EF hand p25-alpha PF05517.7 ETO31040.1 - 0.014 15.6 5.9 1.4 9.1 2.2 2.4 1 1 1 2 2 2 0 p25-alpha EF-hand_4 PF12763.2 ETO31040.1 - 0.22 11.2 4.8 10 5.9 0.1 3.3 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand dUTPase PF00692.14 ETO31041.1 - 0.085 12.3 1.2 4.5 6.7 0.1 2.2 1 1 1 2 2 2 0 dUTPase Sec23_trunk PF04811.10 ETO31043.1 - 8.7e-30 103.8 0.0 5.8e-28 97.8 0.0 2.4 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 ETO31043.1 - 2.2e-16 60.1 0.0 7.1e-16 58.5 0.0 2.0 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 ETO31043.1 - 3.1e-13 49.0 3.9 7e-13 47.9 2.7 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.10 ETO31043.1 - 2.9e-06 26.6 1.7 4.7e-06 25.9 0.0 2.3 3 0 0 3 3 3 1 Sec23/Sec24 helical domain Methyltransf_12 PF08242.7 ETO31043.1 - 0.073 13.5 0.6 0.38 11.2 0.4 2.3 1 0 0 1 1 1 0 Methyltransferase domain AF-4 PF05110.8 ETO31043.1 - 0.14 10.0 3.5 0.21 9.3 2.4 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein MACPF PF01823.14 ETO31043.1 - 0.72 9.4 9.2 0.21 11.2 1.8 2.4 2 0 0 2 2 2 0 MAC/Perforin domain SR-25 PF10500.4 ETO31043.1 - 0.78 9.1 8.1 1.8 7.9 5.6 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Arf PF00025.16 ETO31044.1 - 2e-59 199.7 0.1 2.3e-59 199.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 ETO31044.1 - 1.8e-14 53.2 0.3 4e-11 42.2 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 ETO31044.1 - 7.3e-14 51.4 0.0 8.7e-14 51.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 ETO31044.1 - 3.5e-13 49.2 0.0 3.9e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 ETO31044.1 - 2e-11 44.3 0.0 2.5e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 ETO31044.1 - 2.6e-10 39.8 0.0 3.3e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 ETO31044.1 - 4e-06 26.7 0.0 5.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.14 ETO31044.1 - 0.0027 17.1 0.2 1.4 8.3 0.0 2.1 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 ETO31044.1 - 0.0084 16.0 1.0 0.9 9.4 0.0 2.1 1 1 0 2 2 2 1 AAA domain SRP54 PF00448.17 ETO31044.1 - 0.015 14.7 0.0 0.056 12.8 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NACHT PF05729.7 ETO31044.1 - 0.017 14.7 0.1 3.6 7.2 0.0 2.1 2 0 0 2 2 2 0 NACHT domain GTP_EFTU PF00009.22 ETO31044.1 - 0.03 13.7 0.1 1.2 8.5 0.1 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 ETO31044.1 - 0.042 14.1 0.6 0.15 12.3 0.4 1.8 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.13 ETO31044.1 - 0.043 13.0 0.8 0.23 10.7 0.4 2.0 1 1 1 2 2 2 0 Ferrous iron transport protein B 6PF2K PF01591.13 ETO31044.1 - 0.1 11.6 0.0 0.16 10.9 0.0 1.5 1 1 0 1 1 1 0 6-phosphofructo-2-kinase AAA_23 PF13476.1 ETO31044.1 - 0.11 12.7 0.4 2.6 8.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Apolipoprotein PF01442.13 ETO31045.1 - 0.027 13.9 17.2 0.038 13.4 11.9 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain XRN_N PF03159.13 ETO31045.1 - 0.73 9.1 10.1 0.99 8.7 7.0 1.2 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus DUF883 PF05957.8 ETO31045.1 - 1.1 9.6 5.6 14 6.1 0.0 2.9 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) NIF PF03031.13 ETO31046.1 - 7.1e-39 133.0 0.5 1.4e-38 132.0 0.3 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 ETO31046.1 - 0.0029 17.8 0.0 0.0064 16.7 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Gly_transf_sug PF04488.10 ETO31047.1 - 5.7e-10 39.5 1.3 1.5e-09 38.1 0.0 2.5 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 ETO31047.1 - 0.00048 18.7 7.5 0.01 14.3 0.0 2.9 3 0 0 3 3 3 2 TcdA/TcdB catalytic glycosyltransferase domain CPSF100_C PF13299.1 ETO31047.1 - 0.086 13.0 4.1 0.23 11.6 2.8 1.7 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RRM_1 PF00076.17 ETO31048.1 - 3.7e-34 116.1 0.2 9.9e-19 66.7 0.0 4.5 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO31048.1 - 6e-23 80.4 0.1 6.7e-10 38.6 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO31048.1 - 3e-22 78.3 0.0 1.8e-11 43.8 0.0 4.4 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 ETO31048.1 - 1.4e-09 38.0 2.1 7.2e-05 22.9 0.0 2.7 1 1 0 2 2 2 2 linker between RRM2 and RRM3 domains in RBM39 protein DUF1777 PF08648.7 ETO31048.1 - 0.0053 16.5 19.7 0.0053 16.5 13.6 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF1777) PRP38_assoc PF12871.2 ETO31048.1 - 0.27 11.7 53.7 0.09 13.3 3.4 3.5 3 0 0 3 3 3 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term API5 PF05918.6 ETO31048.1 - 3 6.2 5.8 4.8 5.5 4.1 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) WD40 PF00400.27 ETO31049.1 - 3.2e-56 185.3 18.9 1.2e-11 44.0 0.3 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO31049.1 - 7.1e-13 47.5 2.9 0.00087 17.5 0.2 5.0 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Methyltransf_25 PF13649.1 ETO31049.1 - 0.047 14.0 0.1 7.1 7.0 0.0 3.3 3 0 0 3 3 3 0 Methyltransferase domain DUF727 PF05303.7 ETO31049.1 - 0.083 12.6 0.4 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF727) Glyco_transf_10 PF00852.14 ETO31050.1 - 0.092 11.3 0.0 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 10 (fucosyltransferase) DNA_pol_A_exo1 PF01612.15 ETO31052.1 - 2.4e-08 33.6 0.8 6.2e-08 32.3 0.1 1.9 2 0 0 2 2 2 1 3'-5' exonuclease Myb_DNA-binding PF00249.26 ETO31053.1 - 3.3e-08 33.4 0.1 5.5e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Rifin_STEVOR PF02009.11 ETO31053.1 - 6.5e-05 22.7 5.6 9.2e-05 22.2 3.9 1.3 1 0 0 1 1 1 1 Rifin/stevor family Myb_DNA-bind_6 PF13921.1 ETO31053.1 - 9.1e-05 22.4 0.6 0.00034 20.6 0.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain BatD PF13584.1 ETO31053.1 - 0.0016 17.1 2.3 0.002 16.8 1.6 1.1 1 0 0 1 1 1 1 Oxygen tolerance TMEM154 PF15102.1 ETO31053.1 - 0.0016 18.1 7.3 0.004 16.8 5.0 1.7 1 0 0 1 1 1 1 TMEM154 protein family AMA-1 PF02430.10 ETO31053.1 - 0.0019 17.1 3.8 0.0026 16.7 2.6 1.2 1 0 0 1 1 1 1 Apical membrane antigen 1 ZZ PF00569.12 ETO31053.1 - 0.0023 17.4 0.6 0.0037 16.7 0.4 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type DUF912 PF06024.7 ETO31053.1 - 0.0074 16.3 13.6 0.018 15.1 9.3 1.9 1 1 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Amnionless PF14828.1 ETO31053.1 - 0.013 14.0 0.2 0.016 13.6 0.2 1.1 1 0 0 1 1 1 0 Amnionless DUF4448 PF14610.1 ETO31053.1 - 0.022 14.2 0.1 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF3377 PF11857.3 ETO31053.1 - 0.052 13.1 2.3 0.11 12.1 1.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF3899 PF13038.1 ETO31053.1 - 0.065 13.3 7.5 8.1 6.6 6.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3899) Ammonium_transp PF00909.16 ETO31053.1 - 0.066 11.6 0.2 0.088 11.2 0.1 1.1 1 0 0 1 1 1 0 Ammonium Transporter Family Tmemb_9 PF05434.6 ETO31053.1 - 0.12 12.1 11.2 0.24 11.1 7.8 1.6 1 1 0 1 1 1 0 TMEM9 DUF4349 PF14257.1 ETO31053.1 - 0.18 11.0 0.0 0.25 10.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) LRRC37AB_C PF14914.1 ETO31053.1 - 0.24 10.8 7.0 0.48 9.8 4.9 1.5 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain MENTAL PF10457.4 ETO31053.1 - 0.27 10.8 6.4 0.45 10.0 4.3 1.6 1 1 0 1 1 1 0 Cholesterol-capturing domain MMPL PF03176.10 ETO31053.1 - 1.6 7.3 5.3 2.3 6.8 3.7 1.1 1 0 0 1 1 1 0 MMPL family Tnp_zf-ribbon_2 PF13842.1 ETO31053.1 - 1.7 9.1 4.4 4 7.9 3.1 1.7 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon DUF2839 PF10999.3 ETO31053.1 - 2.1 8.4 4.2 8.3 6.5 2.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2839) GP41 PF00517.12 ETO31053.1 - 2.3 7.7 18.8 3 7.3 12.1 1.9 1 1 1 2 2 2 0 Retroviral envelope protein HemY_N PF07219.8 ETO31053.1 - 5.6 6.5 6.7 41 3.7 4.4 2.2 2 0 0 2 2 2 0 HemY protein N-terminus V_ATPase_I PF01496.14 ETO31054.1 - 2.1e-182 607.8 11.9 2.5e-182 607.6 8.3 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family YbaB_DNA_bd PF02575.11 ETO31054.1 - 1.9 8.4 7.8 0.14 12.0 0.2 2.9 2 1 1 3 3 3 0 YbaB/EbfC DNA-binding family DUF4611 PF15387.1 ETO31055.1 - 3 8.0 6.2 17 5.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Snf7 PF03357.16 ETO31056.1 - 5.8e-12 45.3 7.6 7e-12 45.0 5.3 1.1 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.9 ETO31056.1 - 0.00094 18.6 0.7 0.0014 18.0 0.5 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway PspA_IM30 PF04012.7 ETO31056.1 - 0.0042 16.4 1.5 0.0051 16.1 1.0 1.2 1 0 0 1 1 1 1 PspA/IM30 family FliG_N PF14842.1 ETO31057.1 - 0.016 15.3 1.2 0.023 14.7 0.8 1.2 1 0 0 1 1 1 0 FliG N-terminal domain YlqD PF11068.3 ETO31057.1 - 0.15 12.0 3.7 0.11 12.5 1.6 1.5 1 1 0 1 1 1 0 YlqD protein Snf7 PF03357.16 ETO31057.1 - 1.4 8.3 8.4 0.19 11.1 3.1 1.7 1 1 1 2 2 2 0 Snf7 Nop14 PF04147.7 ETO31058.1 - 0.00071 17.6 22.0 0.00077 17.5 15.3 1.1 1 0 0 1 1 1 1 Nop14-like family DUF2457 PF10446.4 ETO31058.1 - 0.0037 16.0 36.9 0.0048 15.6 25.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) CDC45 PF02724.9 ETO31058.1 - 0.0041 15.2 14.7 0.0044 15.1 10.2 1.0 1 0 0 1 1 1 1 CDC45-like protein CENP-T PF15511.1 ETO31058.1 - 0.0053 16.0 12.6 0.0054 16.0 8.8 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Vfa1 PF08432.5 ETO31058.1 - 0.0059 16.6 8.7 0.0076 16.2 6.0 1.2 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Daxx PF03344.10 ETO31058.1 - 0.0086 14.6 20.1 0.0094 14.4 13.9 1.1 1 0 0 1 1 1 1 Daxx Family Sporozoite_P67 PF05642.6 ETO31058.1 - 0.02 12.7 9.4 0.023 12.6 6.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2796 PF10986.3 ETO31058.1 - 0.028 14.4 9.2 0.033 14.1 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) TRAP_alpha PF03896.11 ETO31058.1 - 0.073 12.0 13.4 0.077 11.9 9.3 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Prp18 PF02840.10 ETO31058.1 - 0.083 12.7 0.5 0.13 12.0 0.4 1.3 1 0 0 1 1 1 0 Prp18 domain DUF4637 PF15470.1 ETO31058.1 - 0.34 10.5 10.3 0.41 10.2 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) SDA1 PF05285.7 ETO31058.1 - 0.37 10.0 22.6 0.42 9.8 15.7 1.1 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.6 ETO31058.1 - 0.45 8.5 20.0 0.54 8.3 13.9 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FYDLN_acid PF09538.5 ETO31058.1 - 0.56 10.8 24.7 0.85 10.2 17.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) HSP90 PF00183.13 ETO31058.1 - 0.58 8.4 13.5 0.62 8.3 9.4 1.1 1 0 0 1 1 1 0 Hsp90 protein GCIP PF13324.1 ETO31058.1 - 0.66 9.1 10.1 0.78 8.9 7.0 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting eIF-3c_N PF05470.7 ETO31058.1 - 0.66 7.9 10.6 0.84 7.6 7.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Paf1 PF03985.8 ETO31058.1 - 0.75 8.4 16.1 0.94 8.1 11.1 1.1 1 0 0 1 1 1 0 Paf1 DUF1510 PF07423.6 ETO31058.1 - 0.87 8.9 18.6 1.1 8.5 12.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Tim54 PF11711.3 ETO31058.1 - 1.2 7.6 6.0 1.4 7.4 4.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Utp14 PF04615.8 ETO31058.1 - 1.7 6.7 16.5 1.9 6.5 11.4 1.1 1 0 0 1 1 1 0 Utp14 protein BUD22 PF09073.5 ETO31058.1 - 2.7 6.9 21.6 3 6.8 15.0 1.2 1 0 0 1 1 1 0 BUD22 Upf2 PF04050.9 ETO31058.1 - 3 7.5 23.8 3.8 7.2 16.5 1.1 1 0 0 1 1 1 0 Up-frameshift suppressor 2 Astro_capsid PF03115.9 ETO31058.1 - 4.1 5.5 9.1 3.9 5.6 6.3 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor CobT PF06213.7 ETO31058.1 - 6.1 5.8 28.5 8.1 5.4 19.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sigma70_ner PF04546.8 ETO31058.1 - 7.5 6.1 30.4 16 5.0 21.1 1.6 1 1 0 1 1 1 0 Sigma-70, non-essential region Runt PF00853.14 ETO31059.1 - 0.091 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Runt domain ABC_tran PF00005.22 ETO31060.1 - 4.9e-28 98.1 0.0 1e-27 97.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 ETO31060.1 - 9.6e-09 35.6 0.0 3.3e-06 27.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 ETO31060.1 - 0.0065 16.8 0.2 0.014 15.6 0.2 1.5 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 ETO31060.1 - 0.019 14.8 0.0 0.06 13.2 0.0 1.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit SRP54 PF00448.17 ETO31060.1 - 0.033 13.6 0.3 0.06 12.7 0.2 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain SMC_N PF02463.14 ETO31060.1 - 0.044 13.0 0.0 0.64 9.2 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 ETO31060.1 - 0.049 13.1 0.2 0.1 12.1 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.1 ETO31060.1 - 0.26 10.2 0.0 15 4.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain ABC2_membrane_3 PF12698.2 ETO31061.1 - 1.3e-10 40.9 3.1 1.6e-10 40.5 2.2 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein Lon_C PF05362.8 ETO31063.1 - 2e-64 216.6 0.0 2.6e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain ChlI PF13541.1 ETO31063.1 - 1.8e-07 30.6 0.0 2.6e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Actin PF00022.14 ETO31064.1 - 1.8e-56 191.2 0.0 2.4e-56 190.8 0.0 1.1 1 0 0 1 1 1 1 Actin TMEM154 PF15102.1 ETO31065.1 - 0.0042 16.7 0.2 0.0085 15.8 0.1 1.4 1 0 0 1 1 1 1 TMEM154 protein family Rifin_STEVOR PF02009.11 ETO31065.1 - 0.0048 16.5 0.0 0.0085 15.7 0.0 1.3 1 0 0 1 1 1 1 Rifin/stevor family Ly49 PF08391.5 ETO31065.1 - 0.013 15.5 0.9 0.038 14.1 0.2 2.0 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region ASFV_J13L PF05568.6 ETO31065.1 - 0.022 14.3 0.1 0.049 13.1 0.0 1.6 1 0 0 1 1 1 0 African swine fever virus J13L protein Vpu PF00558.14 ETO31065.1 - 0.035 13.6 2.3 0.09 12.3 0.2 2.3 2 0 0 2 2 2 0 Vpu protein PIRT PF15099.1 ETO31065.1 - 0.035 13.3 0.6 0.091 11.9 0.4 1.6 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family ODV-E18 PF10717.4 ETO31065.1 - 0.055 12.9 0.1 0.13 11.6 0.1 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF912 PF06024.7 ETO31065.1 - 0.1 12.6 0.2 0.1 12.6 0.1 2.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Peptidase_S49_N PF08496.5 ETO31065.1 - 0.16 11.7 0.8 0.28 10.9 0.6 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SHP PF03579.8 ETO31065.1 - 0.25 10.7 4.9 0.057 12.7 0.7 1.9 2 0 0 2 2 2 0 Small hydrophobic protein Chordopox_A13L PF05961.6 ETO31065.1 - 1.6 8.7 6.0 0.2 11.6 0.3 2.5 3 0 0 3 3 3 0 Chordopoxvirus A13L protein DUF843 PF05814.6 ETO31065.1 - 2.1 8.2 6.9 3.8 7.3 0.2 3.1 3 0 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) Glyco_hydro_2_C PF02836.12 ETO31067.1 - 1.8e-06 27.0 0.1 2.7e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF349 PF03993.7 ETO31070.1 - 0.038 14.1 2.6 0.063 13.4 1.4 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) DUF3584 PF12128.3 ETO31072.1 - 0.0018 15.7 10.2 0.0019 15.6 7.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) TCP PF03634.8 ETO31072.1 - 0.014 15.7 3.4 0.022 15.1 2.4 1.2 1 0 0 1 1 1 0 TCP family transcription factor FlxA PF14282.1 ETO31072.1 - 0.015 15.2 5.6 0.021 14.7 3.9 1.2 1 0 0 1 1 1 0 FlxA-like protein IFT57 PF10498.4 ETO31072.1 - 0.026 13.2 8.0 0.08 11.6 5.6 1.6 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Fib_alpha PF08702.5 ETO31072.1 - 0.063 13.4 3.7 0.099 12.7 2.6 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family P22_AR_N PF10547.4 ETO31072.1 - 0.071 12.9 0.8 0.44 10.3 0.1 2.1 2 0 0 2 2 2 0 P22_AR N-terminal domain Zn_ribbon_2 PF12674.2 ETO31072.1 - 0.11 12.7 3.9 0.72 10.2 0.1 2.5 1 1 1 2 2 2 0 Putative zinc ribbon domain CENP-Q PF13094.1 ETO31072.1 - 0.14 12.1 9.8 0.2 11.6 6.8 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit YlqD PF11068.3 ETO31072.1 - 0.17 11.9 9.0 0.3 11.1 6.2 1.4 1 0 0 1 1 1 0 YlqD protein NAP PF00956.13 ETO31072.1 - 0.19 10.7 5.7 0.29 10.2 4.0 1.2 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) DUF342 PF03961.8 ETO31072.1 - 0.5 8.7 7.8 0.58 8.5 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) OmpH PF03938.9 ETO31072.1 - 0.61 10.0 9.6 0.91 9.4 6.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SprA-related PF12118.3 ETO31072.1 - 0.74 9.0 5.6 0.94 8.7 3.9 1.0 1 0 0 1 1 1 0 SprA-related family HSP70 PF00012.15 ETO31072.1 - 0.77 7.5 6.2 0.91 7.3 4.3 1.1 1 0 0 1 1 1 0 Hsp70 protein ASC PF00858.19 ETO31072.1 - 1 7.9 6.7 1.6 7.2 4.6 1.4 1 1 0 1 1 1 0 Amiloride-sensitive sodium channel SPT16 PF08644.6 ETO31072.1 - 2 8.2 7.4 2.1 8.2 4.3 1.6 1 1 1 2 2 2 0 FACT complex subunit (SPT16/CDC68) HR1 PF02185.11 ETO31072.1 - 2.8 7.7 16.9 0.2 11.4 2.2 2.2 1 1 1 2 2 2 0 Hr1 repeat Prefoldin_2 PF01920.15 ETO31072.1 - 4.3 7.1 17.3 0.099 12.4 1.4 2.3 1 1 1 2 2 2 0 Prefoldin subunit PIN_2 PF10130.4 ETO31072.1 - 4.6 7.2 6.3 5.6 7.0 3.4 1.8 1 1 1 2 2 2 0 PIN domain pRN1_helical PF13010.1 ETO31072.1 - 9.5 5.8 9.6 1.8 8.1 0.6 2.3 1 1 1 2 2 2 0 Primase helical domain DUF3293 PF11697.3 ETO31073.1 - 4.1e-07 30.0 0.8 2.2e-06 27.6 0.5 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3293) U3snoRNP10 PF12397.3 ETO31074.1 - 0.0046 16.8 1.8 0.0062 16.4 0.4 1.7 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 10 Lig_chan PF00060.21 ETO31074.1 - 2.3 7.9 5.7 35 4.0 3.9 2.0 1 1 0 1 1 1 0 Ligand-gated ion channel DUF4381 PF14316.1 ETO31074.1 - 3.2 7.8 11.1 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF3447 PF11929.3 ETO31075.1 - 3.7 7.4 12.0 0.8 9.5 3.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3447) GAS PF13851.1 ETO31076.1 - 2.4e-32 111.8 38.8 2.4e-32 111.8 26.9 2.4 3 0 0 3 3 3 1 Growth-arrest specific micro-tubule binding DUF904 PF06005.7 ETO31076.1 - 0.0016 18.6 7.8 0.0016 18.6 5.4 4.9 3 2 1 4 4 4 1 Protein of unknown function (DUF904) HALZ PF02183.13 ETO31076.1 - 0.0028 17.3 1.6 0.0028 17.3 1.1 4.2 3 1 1 4 4 4 1 Homeobox associated leucine zipper Reo_sigmaC PF04582.7 ETO31076.1 - 0.016 14.3 7.8 0.12 11.5 3.1 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein GIIM PF08388.6 ETO31076.1 - 0.37 10.5 0.1 0.37 10.5 0.1 2.5 3 0 0 3 3 3 0 Group II intron, maturase-specific domain FUSC PF04632.7 ETO31076.1 - 0.39 9.1 2.2 0.38 9.1 0.6 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family DUF305 PF03713.8 ETO31076.1 - 2.7 7.7 13.6 0.41 10.4 1.4 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF305) AAA_13 PF13166.1 ETO31076.1 - 4 5.7 45.3 0.3 9.4 14.6 2.1 1 1 1 2 2 2 0 AAA domain cwf21 PF08312.7 ETO31076.1 - 7.2 6.5 12.2 0.075 12.8 1.1 3.2 3 1 0 3 3 3 0 cwf21 domain Hid1 PF12722.2 ETO31077.1 - 0.02 12.6 3.9 0.027 12.1 2.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Daxx PF03344.10 ETO31077.1 - 0.037 12.5 13.9 0.049 12.1 9.7 1.1 1 0 0 1 1 1 0 Daxx Family Suf PF05843.9 ETO31077.1 - 1.9 8.1 10.2 0.96 9.1 5.5 1.6 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF1510 PF07423.6 ETO31077.1 - 3.4 6.9 20.8 6.6 6.0 14.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Neur_chan_memb PF02932.11 ETO31077.1 - 7.6 6.3 6.5 15 5.4 4.5 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Dynamin_N PF00350.18 ETO31078.1 - 0.057 13.2 0.7 0.13 12.0 0.5 1.6 1 0 0 1 1 1 0 Dynamin family PP_M1 PF03012.9 ETO31078.1 - 0.38 10.0 7.6 5.1 6.3 4.1 2.3 2 0 0 2 2 2 0 Phosphoprotein PBP1_TM PF14812.1 ETO31078.1 - 2.4 8.5 10.7 9.3 6.6 0.0 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.1 ETO31078.1 - 4.1 7.0 8.4 1.9 8.1 2.8 2.4 3 0 0 3 3 3 0 FAM176 family DUF106 PF01956.11 ETO31078.1 - 4.3 6.8 9.4 0.87 9.0 3.2 2.2 2 1 0 2 2 2 0 Integral membrane protein DUF106 START PF01852.14 ETO31079.1 - 1.4e-07 31.1 0.0 2.6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 START domain PPO1_KFDV PF12143.3 ETO31079.1 - 0.03 14.1 0.7 0.062 13.1 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF_B2219) DUF2946 PF11162.3 ETO31079.1 - 1.8 8.7 6.0 3.8 7.7 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2946) Ank_2 PF12796.2 ETO31080.1 - 5e-48 161.3 6.6 3.8e-16 59.1 0.1 4.5 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO31080.1 - 1.1e-23 82.6 0.2 4.7e-06 26.6 0.0 5.7 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.25 ETO31080.1 - 2e-23 80.9 0.5 0.0004 20.0 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 ETO31080.1 - 1e-21 74.8 0.9 0.00022 21.1 0.0 6.9 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.1 ETO31080.1 - 2.7e-21 75.5 0.0 3.1e-11 43.4 0.0 4.7 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Plant_tran PF04827.9 ETO31080.1 - 0.034 13.5 0.0 0.076 12.3 0.0 1.6 1 0 0 1 1 1 0 Plant transposon protein B PF02216.11 ETO31081.1 - 0.012 15.3 0.0 0.22 11.3 0.0 2.6 3 0 0 3 3 3 0 B domain DUF725 PF05267.7 ETO31081.1 - 0.16 11.8 0.1 0.16 11.8 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF725) DASH_Dad3 PF08656.5 ETO31081.1 - 0.28 10.9 5.7 1.3 8.8 0.5 2.6 2 0 0 2 2 2 0 DASH complex subunit Dad3 Mit_KHE1 PF10173.4 ETO31081.1 - 0.31 10.8 4.6 0.33 10.7 1.0 2.2 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related Tubulin PF00091.20 ETO31082.1 - 6.5e-56 189.5 0.0 1.2e-55 188.6 0.0 1.4 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO31082.1 - 1.9e-25 89.3 0.0 3.2e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.1 ETO31082.1 - 0.064 12.1 0.1 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Pik1 PF11522.3 ETO31083.1 - 0.22 11.3 1.3 0.99 9.2 0.1 2.3 2 0 0 2 2 2 0 Yeast phosphatidylinositol-4-OH kinase Pik1 DUF2976 PF11190.3 ETO31083.1 - 1.1 8.8 5.7 2.3 7.8 3.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2976) WD40 PF00400.27 ETO31084.1 - 5e-73 238.5 19.3 3.3e-12 45.7 0.0 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 ETO31084.1 - 2.8e-08 32.3 4.7 0.054 11.6 0.0 4.4 4 1 0 5 5 5 3 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO31084.1 - 9.4e-08 31.9 1.2 0.0075 15.9 0.0 3.3 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 ETO31084.1 - 0.0024 17.0 0.3 0.24 10.4 0.0 2.7 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 ETO31084.1 - 0.0095 14.7 0.6 3.3 6.3 0.0 3.2 3 0 0 3 3 3 1 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO31084.1 - 0.016 13.5 0.3 0.11 10.7 0.0 2.4 3 1 1 4 4 4 0 Cytochrome D1 heme domain IKI3 PF04762.7 ETO31084.1 - 0.073 10.8 0.1 0.19 9.5 0.0 1.7 2 0 0 2 2 2 0 IKI3 family NLE PF08154.7 ETO31085.1 - 7.8e-13 48.2 0.0 1.4e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain DUF1675 PF07897.6 ETO31085.1 - 0.13 12.1 1.9 0.16 11.8 1.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) CDC45 PF02724.9 ETO31086.1 - 0.038 12.0 4.7 0.036 12.1 3.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Tom37_C PF11801.3 ETO31086.1 - 2.1 8.1 8.4 10 5.9 4.6 2.2 2 0 0 2 2 2 0 Tom37 C-terminal domain NARP1 PF12569.3 ETO31086.1 - 4.7 5.8 14.4 7.3 5.2 10.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RR_TM4-6 PF06459.7 ETO31086.1 - 5.4 6.8 11.6 8 6.2 8.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CAP_GLY PF01302.20 ETO31088.1 - 0.013 15.1 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 CAP-Gly domain Daxx PF03344.10 ETO31090.1 - 5.6e-05 21.8 13.9 0.00013 20.5 9.6 1.6 1 0 0 1 1 1 1 Daxx Family DUF2457 PF10446.4 ETO31090.1 - 0.012 14.4 30.1 0.042 12.5 20.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF1517 PF07466.6 ETO31091.1 - 0.24 10.3 4.6 0.26 10.2 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Tmemb_cc2 PF10267.4 ETO31091.1 - 0.99 7.9 6.0 1.2 7.6 4.1 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Macoilin PF09726.4 ETO31091.1 - 1.8 6.7 9.4 1.8 6.7 6.5 1.2 1 0 0 1 1 1 0 Transmembrane protein ORC6 PF05460.8 ETO31091.1 - 1.9 7.4 6.8 2 7.4 4.7 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PAP1 PF08601.5 ETO31091.1 - 3.2 7.3 13.1 3.7 7.1 9.1 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Golgin_A5 PF09787.4 ETO31091.1 - 6.6 5.1 10.3 7.7 4.9 7.1 1.2 1 1 0 1 1 1 0 Golgin subfamily A member 5 DUF2217 PF10265.4 ETO31091.1 - 7.1 5.2 8.5 6.8 5.3 5.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF3643 PF12356.3 ETO31092.1 - 0.38 10.0 6.0 1.2 8.4 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3643) SPRY PF00622.23 ETO31095.1 - 1.9e-26 92.6 0.5 3.4e-26 91.7 0.3 1.5 1 0 0 1 1 1 1 SPRY domain SOBP PF15279.1 ETO31095.1 - 0.078 13.3 25.0 0.018 15.4 13.5 2.3 2 1 0 2 2 2 0 Sine oculis-binding protein HECT PF00632.20 ETO31097.1 - 2.1e-72 244.0 0.0 2e-71 240.7 0.0 2.2 1 1 1 2 2 2 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.13 ETO31097.1 - 5.8e-05 22.1 1.6 0.00014 20.8 1.1 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others 2OG-FeII_Oxy_3 PF13640.1 ETO31098.1 - 8.9e-14 51.8 0.0 2.6e-13 50.3 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 ETO31098.1 - 0.0013 18.2 5.0 0.01 15.4 3.5 2.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2334 PF10096.4 ETO31100.1 - 0.012 15.0 0.1 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) GrpE PF01025.14 ETO31100.1 - 0.13 11.7 3.3 0.14 11.6 2.3 1.0 1 0 0 1 1 1 0 GrpE Radial_spoke_3 PF06098.6 ETO31100.1 - 0.17 10.8 2.0 0.18 10.7 1.4 1.0 1 0 0 1 1 1 0 Radial spoke protein 3 TMEM247 PF15444.1 ETO31100.1 - 1.1 9.0 4.3 1.1 9.0 3.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 247 Aldolase_II PF00596.16 ETO31101.1 - 3.5e-08 33.2 0.0 4.4e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain HAP PF03866.8 ETO31101.1 - 0.02 14.6 0.0 0.025 14.3 0.0 1.1 1 0 0 1 1 1 0 Hydrophobic abundant protein (HAP) HEM4 PF02602.10 ETO31102.1 - 7.1e-17 61.4 0.0 8.6e-17 61.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD DUF3796 PF12676.2 ETO31104.1 - 2.7 8.2 8.1 5.2 7.3 5.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) MIF4G PF02854.14 ETO31105.1 - 5e-24 84.8 6.4 1.2e-23 83.6 4.5 1.7 1 0 0 1 1 1 1 MIF4G domain Methyltransf_11 PF08241.7 ETO31106.1 - 5.5e-12 46.0 0.0 1.1e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETO31106.1 - 1.7e-07 31.0 0.0 2.8e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO31106.1 - 4e-05 23.2 0.0 6.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO31106.1 - 0.00014 22.2 0.0 0.00051 20.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETO31106.1 - 0.00017 20.8 0.0 0.00033 19.8 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 ETO31106.1 - 0.00058 20.1 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 ETO31106.1 - 0.078 11.2 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF1869 PF08956.5 ETO31107.1 - 0.047 13.2 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1869) Nol1_Nop2_Fmu PF01189.12 ETO31108.1 - 3.9e-06 26.4 0.0 6.9e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 NOL1/NOP2/sun family FlxA PF14282.1 ETO31108.1 - 0.058 13.3 0.3 0.15 11.9 0.2 1.7 1 0 0 1 1 1 0 FlxA-like protein Amidase PF01425.16 ETO31109.1 - 5.4e-46 157.3 0.0 2.3e-26 92.6 0.0 2.0 2 0 0 2 2 2 2 Amidase DUF588 PF04535.7 ETO31109.1 - 0.11 12.0 0.3 0.41 10.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF588) Amidase PF01425.16 ETO31110.1 - 6.8e-12 44.9 0.0 7.6e-12 44.8 0.0 1.0 1 0 0 1 1 1 1 Amidase FGE-sulfatase PF03781.11 ETO31112.1 - 4.8e-62 209.6 0.8 4.8e-62 209.6 0.6 1.4 2 0 0 2 2 2 1 Sulfatase-modifying factor enzyme 1 SR-25 PF10500.4 ETO31113.1 - 0.0077 15.7 5.1 0.0091 15.4 3.5 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4102 PF13356.1 ETO31113.1 - 0.06 13.2 0.0 5.9 6.8 0.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4102) DUF755 PF05501.6 ETO31113.1 - 0.076 13.0 9.3 0.12 12.4 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) V-set_CD47 PF08204.6 ETO31113.1 - 0.36 10.6 6.2 0.11 12.2 2.3 1.7 1 1 1 2 2 2 0 CD47 immunoglobulin-like domain PT PF04886.7 ETO31114.1 - 1.2e-13 50.0 181.6 1.3e-08 34.0 14.6 11.0 3 3 4 7 7 7 5 PT repeat WD40 PF00400.27 ETO31115.1 - 3.2e-50 166.2 30.8 3.3e-10 39.4 0.1 7.3 6 1 1 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO31115.1 - 2.6e-07 29.1 8.5 0.091 10.8 0.2 4.6 1 1 3 5 5 5 4 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO31115.1 - 0.0014 18.9 0.1 0.0014 18.9 0.1 2.6 2 0 0 2 2 2 1 TRAF-type zinc finger DUF342 PF03961.8 ETO31115.1 - 0.012 14.0 9.5 0.018 13.4 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) OmpH PF03938.9 ETO31115.1 - 0.023 14.6 10.4 0.041 13.8 7.2 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF413 PF04219.7 ETO31115.1 - 0.6 9.9 7.2 1.8 8.3 1.6 2.5 1 1 1 2 2 2 0 Protein of unknown function, DUF LMBR1 PF04791.11 ETO31115.1 - 0.89 8.0 2.8 1.2 7.6 2.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein PhoU PF01895.14 ETO31115.1 - 1.6 9.2 9.1 6 7.3 0.5 2.5 2 0 0 2 2 2 0 PhoU domain DUF4407 PF14362.1 ETO31115.1 - 9.9 5.0 7.3 19 4.0 5.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sarcoglycan_2 PF05510.8 ETO31116.1 - 0.0055 15.0 2.6 0.006 14.9 1.8 1.0 1 0 0 1 1 1 1 Sarcoglycan alpha/epsilon CDV3 PF15359.1 ETO31116.1 - 0.063 13.3 4.8 0.093 12.8 3.3 1.4 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 DRY_EERY PF09750.4 ETO31116.1 - 0.083 12.9 4.2 0.085 12.9 2.4 1.4 1 1 0 1 1 1 0 Alternative splicing regulator RP-C_C PF11800.3 ETO31116.1 - 0.21 11.2 5.8 0.22 11.2 4.0 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region CAF-1_p150 PF11600.3 ETO31116.1 - 0.31 10.4 15.8 0.37 10.1 11.0 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RNA_pol_3_Rpc31 PF11705.3 ETO31116.1 - 0.52 10.2 12.7 0.56 10.1 8.8 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 AAA_11 PF13086.1 ETO31116.1 - 0.61 9.6 6.7 0.7 9.4 4.7 1.0 1 0 0 1 1 1 0 AAA domain Med2 PF11214.3 ETO31116.1 - 1.5 8.9 11.3 1.9 8.5 7.8 1.3 1 0 0 1 1 1 0 Mediator complex subunit 2 HAUS6_N PF14661.1 ETO31116.1 - 3.4 6.9 7.5 4 6.7 5.2 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus UbiA PF01040.13 ETO31117.1 - 2.1e-18 66.5 8.5 2.1e-18 66.5 5.9 1.5 1 1 1 2 2 2 1 UbiA prenyltransferase family WD40 PF00400.27 ETO31118.1 - 7.8e-64 209.4 27.4 2e-11 43.3 0.3 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO31118.1 - 8.7e-12 43.9 11.4 3.4e-05 22.1 0.5 5.2 2 1 3 5 5 5 5 Nucleoporin Nup120/160 Peptidase_C14 PF00656.17 ETO31119.1 - 8.2e-12 45.3 0.4 1.7e-11 44.3 0.3 1.6 1 1 0 1 1 1 1 Caspase domain NACHT PF05729.7 ETO31120.1 - 5.9e-06 26.0 0.0 0.062 12.9 0.0 2.6 1 1 1 2 2 2 2 NACHT domain AAA_18 PF13238.1 ETO31120.1 - 4.3e-05 23.8 5.3 0.00026 21.2 0.0 3.8 3 1 1 4 4 4 1 AAA domain AAA_22 PF13401.1 ETO31120.1 - 0.00027 21.0 0.0 0.0016 18.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ETO31120.1 - 0.00091 20.0 0.6 0.011 16.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 ETO31120.1 - 0.0011 19.2 0.2 0.0051 17.1 0.0 2.2 2 0 0 2 2 2 1 ABC transporter UPF0079 PF02367.12 ETO31120.1 - 0.0049 16.4 0.1 0.016 14.8 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_5 PF07728.9 ETO31120.1 - 0.029 14.0 0.0 1.2 8.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 ETO31120.1 - 1.4 9.1 6.2 0.55 10.4 0.0 3.5 3 1 0 3 3 3 0 RNA helicase TAFII28 PF04719.9 ETO31121.1 - 0.076 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Daxx PF03344.10 ETO31123.1 - 0.004 15.7 14.9 0.0043 15.6 10.3 1.0 1 0 0 1 1 1 1 Daxx Family DDRGK PF09756.4 ETO31123.1 - 0.0077 15.6 9.5 0.0095 15.3 6.6 1.2 1 0 0 1 1 1 1 DDRGK domain Borrelia_P83 PF05262.6 ETO31123.1 - 0.075 11.2 8.9 0.083 11.1 6.2 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein CDC27 PF09507.5 ETO31123.1 - 0.41 9.8 14.2 0.58 9.3 9.8 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 NPR3 PF03666.8 ETO31123.1 - 0.54 8.7 4.4 0.8 8.1 3.0 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.7 ETO31123.1 - 2.2 8.0 11.4 3.3 7.5 7.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ATP-synt_E PF05680.7 ETO31123.1 - 2.2 8.2 7.6 4 7.4 5.3 1.5 1 0 0 1 1 1 0 ATP synthase E chain Prog_receptor PF02161.10 ETO31123.1 - 2.6 6.7 5.5 3.4 6.3 3.8 1.1 1 0 0 1 1 1 0 Progesterone receptor Ycf1 PF05758.7 ETO31123.1 - 2.7 5.5 7.1 2.8 5.5 4.9 1.1 1 0 0 1 1 1 0 Ycf1 Leader_Thr PF08254.6 ETO31123.1 - 8.9 6.1 11.9 20 5.0 8.3 1.5 1 0 0 1 1 1 0 Threonine leader peptide Barstar PF01337.13 ETO31124.1 - 0.033 14.0 0.1 0.09 12.6 0.0 1.8 2 1 0 2 2 2 0 Barstar (barnase inhibitor) Scm3 PF10384.4 ETO31124.1 - 0.15 11.5 0.2 0.42 10.1 0.2 1.7 1 0 0 1 1 1 0 Centromere protein Scm3 zf-RING_5 PF14634.1 ETO31127.1 - 6.1e-06 25.8 3.0 6.1e-06 25.8 2.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 ETO31127.1 - 1.7e-05 24.7 2.9 1.7e-05 24.7 2.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO31127.1 - 0.00016 21.4 4.8 0.00017 21.3 2.1 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 ETO31127.1 - 0.00022 20.8 1.8 0.00022 20.8 1.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO31127.1 - 0.00034 20.1 2.3 0.00034 20.1 1.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 ETO31127.1 - 0.0027 17.4 0.8 0.0091 15.6 0.6 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 ETO31127.1 - 0.053 13.4 2.6 0.13 12.1 1.8 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Telomerase_RBD PF12009.3 ETO31131.1 - 0.024 14.5 0.9 0.026 14.4 0.6 1.0 1 0 0 1 1 1 0 Telomerase ribonucleoprotein complex - RNA binding domain KaiC PF06745.8 ETO31131.1 - 0.063 12.3 0.2 0.065 12.3 0.1 1.0 1 0 0 1 1 1 0 KaiC CDtoxinA PF03498.9 ETO31131.1 - 0.09 12.1 1.9 0.084 12.2 1.4 1.0 1 0 0 1 1 1 0 Cytolethal distending toxin A/C family DHC PF09626.5 ETO31131.1 - 0.37 11.4 5.5 0.4 11.3 3.8 1.1 1 0 0 1 1 1 0 Dihaem cytochrome c SCRL PF06876.7 ETO31131.1 - 1.4 8.9 6.4 1.9 8.5 4.5 1.3 1 1 0 1 1 1 0 Plant self-incompatibility response (SCRL) protein DUF2701 PF10857.3 ETO31134.1 - 0.061 13.1 0.3 0.11 12.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2701) Fe-S_assembly PF04384.8 ETO31135.1 - 0.016 15.5 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 Iron-sulphur cluster assembly Daxx PF03344.10 ETO31136.1 - 0.043 12.3 19.6 0.047 12.1 13.6 1.1 1 0 0 1 1 1 0 Daxx Family NAM-associated PF14303.1 ETO31136.1 - 0.066 13.5 16.4 0.094 13.0 11.4 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Dsh_C PF12316.3 ETO31136.1 - 0.39 10.7 12.6 0.13 12.3 6.5 1.8 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Ycf1 PF05758.7 ETO31136.1 - 0.67 7.6 7.6 0.64 7.6 5.3 1.0 1 0 0 1 1 1 0 Ycf1 DUF3337 PF11816.3 ETO31136.1 - 0.75 9.1 13.8 1.3 8.3 9.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) RR_TM4-6 PF06459.7 ETO31136.1 - 0.82 9.5 12.1 1.2 8.9 8.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cellulose_synt PF03552.9 ETO31136.1 - 1.7 6.8 7.0 2.2 6.4 4.9 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF1510 PF07423.6 ETO31136.1 - 2.7 7.2 23.8 3.8 6.8 16.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CKAP2_C PF15297.1 ETO31136.1 - 3 6.5 13.3 4.8 5.8 9.2 1.2 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus CDC45 PF02724.9 ETO31136.1 - 6.8 4.5 18.4 8.8 4.2 12.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 ETO31136.1 - 8.1 4.2 21.9 10 3.8 15.2 1.1 1 0 0 1 1 1 0 Nop14-like family SR-25 PF10500.4 ETO31136.1 - 9.2 5.6 26.1 1.8 8.0 6.8 2.2 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein FCP1_C PF09309.5 ETO31137.1 - 0.13 11.5 5.5 0.16 11.2 3.8 1.1 1 0 0 1 1 1 0 FCP1, C-terminal WW PF00397.21 ETO31138.1 - 1.1e-11 44.4 3.9 2.3e-11 43.3 2.7 1.6 1 0 0 1 1 1 1 WW domain XPG_I_2 PF12813.2 ETO31139.1 - 0.00019 20.9 0.0 0.00051 19.6 0.0 1.7 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.13 ETO31139.1 - 0.011 15.7 0.3 0.044 13.8 0.0 2.2 2 0 0 2 2 2 0 XPG I-region DUF3439 PF11921.3 ETO31139.1 - 2 8.1 36.3 0.18 11.5 9.7 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF3439) AMMECR1 PF01871.12 ETO31141.1 - 0.0069 15.5 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 AMMECR1 Mito_carr PF00153.22 ETO31142.1 - 1.5e-36 123.9 0.2 1.6e-19 69.3 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein Folate_carrier PF01770.13 ETO31143.1 - 2.9 6.2 4.4 4.3 5.7 3.1 1.4 1 0 0 1 1 1 0 Reduced folate carrier 4HBT_2 PF13279.1 ETO31146.1 - 8e-19 68.2 0.1 1.1e-18 67.8 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 ETO31146.1 - 7.6e-06 25.9 0.0 1.9e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Thioesterase superfamily DHC_N2 PF08393.8 ETO31148.1 - 1.5e-22 79.6 1.2 1.5e-22 79.6 0.8 3.4 3 1 1 4 4 4 1 Dynein heavy chain, N-terminal region 2 ELH PF02323.10 ETO31148.1 - 0.088 11.9 4.5 0.15 11.1 3.1 1.3 1 0 0 1 1 1 0 Egg-laying hormone precursor DHC_N2 PF08393.8 ETO31149.1 - 5.3e-89 298.5 10.3 5.2e-65 219.5 1.3 2.8 2 1 0 2 2 2 2 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 ETO31150.1 - 1.8e-76 256.7 1.3 1.1e-66 224.6 0.1 2.1 2 0 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 ETO31150.1 - 0.0059 16.3 0.0 0.021 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Kelch_4 PF13418.1 ETO31151.1 - 8.3e-06 25.4 0.2 0.86 9.4 0.0 4.3 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO31151.1 - 0.012 15.7 0.3 10 6.4 0.0 3.7 3 0 0 3 3 3 0 Galactose oxidase, central domain DUF2817 PF10994.3 ETO31154.1 - 3.9e-38 131.3 1.4 1.9e-35 122.5 1.0 3.2 1 1 0 1 1 1 1 Protein of unknown function (DUF2817) Peptidase_M14 PF00246.19 ETO31154.1 - 0.016 14.7 0.2 0.038 13.6 0.1 1.5 1 1 0 1 1 1 0 Zinc carboxypeptidase CytochromB561_N PF09786.4 ETO31155.1 - 0.061 11.7 5.5 0.072 11.5 3.8 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Macoilin PF09726.4 ETO31155.1 - 0.68 8.1 7.7 0.83 7.8 5.3 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF2201_N PF13203.1 ETO31155.1 - 0.81 8.8 7.9 0.94 8.5 5.5 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF2981 PF11200.3 ETO31155.1 - 1.3 8.0 4.3 1.4 7.9 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Sec7_N PF12783.2 ETO31157.1 - 5.5e-08 32.4 4.2 1.5e-07 30.9 1.7 2.3 2 1 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Sec7 PF01369.15 ETO31158.1 - 2.7e-33 115.2 0.1 6.6e-33 113.9 0.0 1.6 1 0 0 1 1 1 1 Sec7 domain DUF1282 PF06930.7 ETO31159.1 - 0.082 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) Ank_2 PF12796.2 ETO31160.1 - 4.6e-08 33.2 0.4 0.00033 20.9 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO31160.1 - 3.3e-05 23.9 0.3 0.0002 21.4 0.0 2.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 ETO31160.1 - 0.00013 21.5 0.3 0.21 11.4 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 ETO31160.1 - 0.00037 20.4 0.2 0.72 10.2 0.0 3.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 ETO31160.1 - 0.0012 19.2 0.3 0.014 15.9 0.0 2.4 2 1 1 3 3 3 1 Ankyrin repeats (many copies) HELP PF03451.9 ETO31162.1 - 0.005 16.3 0.0 0.013 14.9 0.0 1.7 1 0 0 1 1 1 1 HELP motif SET_assoc PF11767.3 ETO31163.1 - 0.077 12.3 0.0 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Hira PF07569.6 ETO31164.1 - 0.089 11.9 0.3 1.1 8.3 0.0 2.2 2 1 0 2 2 2 0 TUP1-like enhancer of split WD40 PF00400.27 ETO31164.1 - 0.13 12.1 6.2 4.1 7.4 0.1 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat Thioredoxin PF00085.15 ETO31165.1 - 2.2e-46 155.8 4.8 1.3e-22 79.3 0.1 3.7 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 ETO31165.1 - 4.5e-24 85.2 12.8 2.5e-17 63.3 0.9 3.9 4 1 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_7 PF13899.1 ETO31165.1 - 9.6e-16 57.5 1.7 8.3e-08 32.1 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 ETO31165.1 - 1e-14 54.6 6.7 6e-09 36.0 0.2 4.4 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 ETO31165.1 - 1.3e-14 54.0 7.6 2.7e-07 30.5 0.1 4.6 3 2 1 4 4 4 3 Thioredoxin-like AhpC-TSA PF00578.16 ETO31165.1 - 6.5e-08 32.2 3.8 4.8e-06 26.2 0.1 3.0 2 2 0 2 2 2 2 AhpC/TSA family ERp29_N PF07912.8 ETO31165.1 - 1.1e-07 31.7 4.8 1e-05 25.4 0.1 3.4 3 1 0 3 3 3 2 ERp29, N-terminal domain Thioredox_DsbH PF03190.10 ETO31165.1 - 2.7e-05 23.9 0.2 5.7e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Redoxin PF08534.5 ETO31165.1 - 4.6e-05 22.9 0.3 0.0011 18.5 0.0 2.5 2 0 0 2 2 2 1 Redoxin Thioredoxin_9 PF14595.1 ETO31165.1 - 0.011 15.2 0.0 0.79 9.2 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin TraF PF13728.1 ETO31165.1 - 0.04 13.4 0.5 4.2 6.7 0.0 3.1 4 0 0 4 4 4 0 F plasmid transfer operon protein TMF_DNA_bd PF12329.3 ETO31166.1 - 0.0026 17.5 9.9 0.0026 17.5 6.9 2.3 1 1 1 2 2 2 1 TATA element modulatory factor 1 DNA binding Baculo_PEP_C PF04513.7 ETO31166.1 - 0.0034 17.2 10.9 0.0083 15.9 7.5 1.6 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Nbl1_Borealin_N PF10444.4 ETO31166.1 - 0.0067 15.7 1.4 0.02 14.2 1.0 1.8 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal DUF3584 PF12128.3 ETO31166.1 - 0.0071 13.7 9.6 0.0088 13.4 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.7 ETO31166.1 - 0.014 15.1 12.2 0.17 11.6 8.4 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 ETO31166.1 - 0.016 14.1 7.2 0.023 13.6 5.0 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 ETO31166.1 - 0.019 14.0 9.4 0.023 13.7 6.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Mnd1 PF03962.10 ETO31166.1 - 0.028 14.0 8.7 0.041 13.5 6.1 1.3 1 0 0 1 1 1 0 Mnd1 family HOOK PF05622.7 ETO31166.1 - 0.064 11.0 10.3 0.07 10.9 7.1 1.0 1 0 0 1 1 1 0 HOOK protein DUF1732 PF08340.6 ETO31166.1 - 0.077 12.8 7.7 0.71 9.7 5.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF1732) Phage_GP20 PF06810.6 ETO31166.1 - 0.093 12.1 15.4 0.12 11.8 3.9 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 Herpes_BLRF2 PF05812.7 ETO31166.1 - 0.095 12.5 6.4 0.14 11.9 4.5 1.3 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein GvpO PF05800.6 ETO31166.1 - 0.099 12.5 0.9 0.16 11.8 0.6 1.6 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpO DUF2951 PF11166.3 ETO31166.1 - 0.1 12.4 10.3 1.1 9.2 0.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) IncA PF04156.9 ETO31166.1 - 0.1 12.2 11.3 0.14 11.7 7.8 1.3 1 0 0 1 1 1 0 IncA protein Suppressor_APC PF11414.3 ETO31166.1 - 0.1 12.3 2.1 0.17 11.6 1.1 1.7 1 1 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein WXG100 PF06013.7 ETO31166.1 - 0.1 12.5 3.1 0.21 11.6 0.7 2.1 1 1 0 2 2 2 0 Proteins of 100 residues with WXG Corona_S2 PF01601.11 ETO31166.1 - 0.11 10.6 8.4 0.04 12.0 3.3 1.7 1 1 1 2 2 2 0 Coronavirus S2 glycoprotein UVR PF02151.14 ETO31166.1 - 0.11 12.0 3.8 9.3 5.9 0.1 3.4 3 0 0 3 3 3 0 UvrB/uvrC motif DUF3086 PF11285.3 ETO31166.1 - 0.11 11.2 4.1 1.9 7.2 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3086) Vps51 PF08700.6 ETO31166.1 - 0.12 12.1 8.8 0.12 12.2 3.0 2.3 1 1 1 2 2 2 0 Vps51/Vps67 LUC7 PF03194.10 ETO31166.1 - 0.14 11.6 5.9 0.16 11.4 4.1 1.1 1 0 0 1 1 1 0 LUC7 N_terminus ScpA_ScpB PF02616.9 ETO31166.1 - 0.14 11.6 5.5 0.17 11.4 3.8 1.0 1 0 0 1 1 1 0 ScpA/B protein Apolipoprotein PF01442.13 ETO31166.1 - 0.15 11.5 5.1 0.3 10.5 3.6 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain IFT57 PF10498.4 ETO31166.1 - 0.15 10.7 13.5 0.19 10.4 9.4 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Spc7 PF08317.6 ETO31166.1 - 0.15 10.6 13.2 0.21 10.1 9.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein AKNA PF12443.3 ETO31166.1 - 0.18 11.8 5.7 0.18 11.8 2.0 2.2 1 1 1 2 2 2 0 AT-hook-containing transcription factor Seryl_tRNA_N PF02403.17 ETO31166.1 - 0.19 11.7 14.6 0.14 12.1 4.3 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GldM_N PF12081.3 ETO31166.1 - 0.23 10.9 8.7 0.33 10.4 6.0 1.3 1 1 0 1 1 1 0 GldM N-terminal domain EAP30 PF04157.11 ETO31166.1 - 0.24 10.5 8.1 0.13 11.3 3.8 1.8 1 1 1 2 2 2 0 EAP30/Vps36 family DUF1664 PF07889.7 ETO31166.1 - 0.3 10.9 12.3 0.074 12.8 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) bZIP_1 PF00170.16 ETO31166.1 - 0.32 10.9 10.0 0.08 12.9 1.4 2.9 2 1 0 2 2 2 0 bZIP transcription factor DUF4407 PF14362.1 ETO31166.1 - 0.36 9.7 3.6 0.42 9.5 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ACCA PF03255.9 ETO31166.1 - 0.37 10.3 9.2 0.38 10.3 1.1 2.6 1 1 2 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit TMCO5 PF14992.1 ETO31166.1 - 0.38 9.8 9.4 0.51 9.4 6.5 1.2 1 0 0 1 1 1 0 TMCO5 family TBPIP PF07106.8 ETO31166.1 - 0.41 10.1 15.9 0.81 9.2 4.8 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) THOC7 PF05615.8 ETO31166.1 - 0.42 10.8 7.9 1.1 9.5 5.5 1.6 1 1 0 1 1 1 0 Tho complex subunit 7 COG5 PF10392.4 ETO31166.1 - 0.45 10.4 7.8 4.5 7.2 2.5 2.1 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Tropomyosin_1 PF12718.2 ETO31166.1 - 0.69 9.7 15.7 1.6 8.5 5.7 1.9 1 1 1 2 2 2 0 Tropomyosin like FliJ PF02050.11 ETO31166.1 - 0.7 9.9 9.4 2.7 8.0 6.5 1.9 1 1 0 1 1 1 0 Flagellar FliJ protein V_ATPase_I PF01496.14 ETO31166.1 - 0.72 7.6 7.9 0.81 7.4 5.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 ETO31166.1 - 0.78 10.1 13.1 3.9 7.8 1.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Phage_GPO PF05929.6 ETO31166.1 - 0.81 8.8 5.3 1.1 8.4 3.7 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Syntaxin PF00804.20 ETO31166.1 - 0.95 9.6 17.8 28 4.9 12.3 2.3 1 1 0 1 1 1 0 Syntaxin Ax_dynein_light PF10211.4 ETO31166.1 - 0.95 9.2 12.5 2.5 7.9 4.3 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain TMF_TATA_bd PF12325.3 ETO31166.1 - 1 9.1 13.0 0.39 10.4 5.0 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1515 PF07439.6 ETO31166.1 - 1 9.1 3.8 0.98 9.2 0.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Rootletin PF15035.1 ETO31166.1 - 1 9.2 8.9 3.3 7.6 4.3 2.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Flagellin_C PF00700.16 ETO31166.1 - 1.1 9.4 9.1 0.43 10.7 1.7 2.7 2 1 1 3 3 3 0 Bacterial flagellin C-terminal helical region Filo_VP35 PF02097.10 ETO31166.1 - 1.3 8.1 5.4 1.5 7.9 3.8 1.1 1 0 0 1 1 1 0 Filoviridae VP35 Fib_alpha PF08702.5 ETO31166.1 - 1.3 9.1 14.1 5.3 7.1 9.7 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family TMPIT PF07851.8 ETO31166.1 - 1.4 7.9 8.1 1.7 7.6 5.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF904 PF06005.7 ETO31166.1 - 1.4 9.2 16.8 1.4e+02 2.8 11.6 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF2450 PF10475.4 ETO31166.1 - 1.7 7.4 8.4 3.4 6.4 5.8 1.4 1 1 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) DUF2203 PF09969.4 ETO31166.1 - 1.7 8.8 7.3 8.3 6.6 0.4 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) COG2 PF06148.6 ETO31166.1 - 1.8 8.4 6.7 6 6.7 4.5 1.8 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Prefoldin PF02996.12 ETO31166.1 - 2 8.1 11.4 0.88 9.2 1.6 3.1 1 1 2 3 3 3 0 Prefoldin subunit NPV_P10 PF05531.7 ETO31166.1 - 2.2 8.5 8.7 15 5.9 5.8 2.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.4 ETO31166.1 - 2.9 8.0 13.5 1.5 8.9 4.2 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Striatin PF08232.7 ETO31166.1 - 3.6 7.9 10.8 6.3 7.1 7.5 1.5 1 1 0 1 1 1 0 Striatin family Matrilin_ccoil PF10393.4 ETO31166.1 - 4.9 6.5 6.7 1.4 8.3 0.2 2.9 3 1 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF948 PF06103.6 ETO31166.1 - 5.6 6.9 9.5 7.3 6.5 3.7 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Spc24 PF08286.6 ETO31166.1 - 7.6 6.2 15.7 9.2 5.9 5.6 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 LTD PF00932.14 ETO31167.1 - 0.025 14.6 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 Lamin Tail Domain DUF2758 PF10957.3 ETO31167.1 - 0.67 9.8 7.4 0.075 12.8 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2758) PA26 PF04636.8 ETO31169.1 - 1.4e-29 103.0 0.1 1.7e-29 102.8 0.1 1.0 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) Neur_chan_memb PF02932.11 ETO31170.1 - 0.067 13.0 0.2 0.067 13.0 0.1 2.8 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region RSN1_TM PF13967.1 ETO31170.1 - 0.1 12.1 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport ETRAMP PF09716.5 ETO31170.1 - 0.19 11.7 1.0 0.79 9.7 0.7 2.2 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Mucin PF01456.12 ETO31170.1 - 0.51 10.1 3.7 0.19 11.5 0.5 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein Peptidase_M48 PF01435.13 ETO31171.1 - 8.5e-33 113.8 0.1 1.3e-32 113.1 0.1 1.2 1 1 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 ETO31171.1 - 0.0046 15.9 0.3 0.0068 15.4 0.2 1.2 1 0 0 1 1 1 1 BlaR1 peptidase M56 DUF2268 PF10026.4 ETO31171.1 - 0.099 12.0 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) UQ_con PF00179.21 ETO31173.1 - 4.7e-34 116.8 1.0 4.8e-23 81.1 0.1 3.1 3 0 0 3 3 3 3 Ubiquitin-conjugating enzyme Nup160 PF11715.3 ETO31173.1 - 0.03 12.4 0.0 0.12 10.4 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Methyltransf_31 PF13847.1 ETO31174.1 - 2.9e-12 46.4 0.4 9.8e-12 44.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO31174.1 - 6.4e-10 39.6 0.0 1.2e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO31174.1 - 6.8e-10 39.3 0.0 7.1e-09 36.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETO31174.1 - 1.6e-09 38.0 0.0 3.8e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETO31174.1 - 3.8e-09 36.9 0.0 2.7e-08 34.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETO31174.1 - 3.8e-09 36.4 0.1 1e-08 35.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 ETO31174.1 - 0.0021 17.1 0.1 0.0077 15.2 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_32 PF13679.1 ETO31174.1 - 0.003 17.2 0.0 0.0068 16.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 ETO31174.1 - 0.013 15.5 0.1 0.05 13.5 0.1 2.0 1 1 0 1 1 1 0 FtsJ-like methyltransferase NodS PF05401.6 ETO31174.1 - 0.033 13.5 0.0 0.11 11.9 0.0 1.7 1 1 0 1 1 1 0 Nodulation protein S (NodS) MTS PF05175.9 ETO31174.1 - 0.084 12.2 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.14 ETO31174.1 - 0.094 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF3225 PF11533.3 ETO31175.1 - 0.13 11.8 1.0 0.19 11.4 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3225) Ank_2 PF12796.2 ETO31176.1 - 4.5e-20 71.7 7.9 8.8e-10 38.7 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETO31176.1 - 7.1e-19 66.6 7.5 6.6e-06 25.6 0.2 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 ETO31176.1 - 5.3e-18 64.6 4.8 0.00012 22.1 0.2 4.3 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO31176.1 - 3.5e-17 62.3 1.4 9.2e-06 26.0 0.0 4.4 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO31176.1 - 8.9e-12 44.0 5.4 0.0063 16.6 0.1 4.8 4 0 0 4 4 4 3 Ankyrin repeat Peptidase_A22B PF04258.8 ETO31177.1 - 0.034 13.5 0.9 0.04 13.3 0.6 1.1 1 0 0 1 1 1 0 Signal peptide peptidase Phospholamban PF04272.9 ETO31177.1 - 0.33 10.4 5.6 1 8.8 3.9 1.8 1 0 0 1 1 1 0 Phospholamban DUF1554 PF07588.6 ETO31177.1 - 0.44 10.0 5.7 4.3 6.8 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1554) WD40 PF00400.27 ETO31178.1 - 9.5e-29 98.2 8.4 3.9e-11 42.3 0.5 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO31178.1 - 1.6e-05 23.2 0.1 0.027 12.6 0.0 3.0 2 1 0 3 3 3 3 Nucleoporin Nup120/160 Kelch_2 PF07646.10 ETO31180.1 - 0.043 13.6 4.1 1 9.2 0.4 3.7 3 1 1 4 4 4 0 Kelch motif Kelch_1 PF01344.20 ETO31180.1 - 0.12 11.9 10.1 0.087 12.3 2.0 3.6 4 0 0 4 4 4 0 Kelch motif Kelch_6 PF13964.1 ETO31180.1 - 0.18 12.0 10.6 0.6 10.3 0.0 3.9 5 0 0 5 5 5 0 Kelch motif Kelch_5 PF13854.1 ETO31180.1 - 1.3 9.0 7.4 21 5.2 0.0 4.0 4 1 0 4 4 4 0 Kelch motif SPRY PF00622.23 ETO31181.1 - 0.046 13.8 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 SPRY domain GAS PF13851.1 ETO31182.1 - 0.0062 15.7 94.2 0.21 10.7 12.0 6.5 2 1 4 6 6 6 5 Growth-arrest specific micro-tubule binding IncA PF04156.9 ETO31182.1 - 0.75 9.3 93.2 0.18 11.3 13.3 5.7 2 1 3 5 5 5 0 IncA protein DUF1515 PF07439.6 ETO31182.1 - 3.7 7.3 21.6 9.3 6.1 8.1 4.0 3 2 0 3 3 3 0 Protein of unknown function (DUF1515) Fib_alpha PF08702.5 ETO31183.1 - 0.00047 20.2 12.4 0.00071 19.7 8.6 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.3 ETO31183.1 - 0.00075 19.2 17.0 0.0063 16.2 6.4 3.0 1 1 2 3 3 3 1 TATA element modulatory factor 1 DNA binding CENP-Q PF13094.1 ETO31183.1 - 0.0016 18.5 10.1 0.084 12.8 1.9 2.2 2 0 0 2 2 2 2 CENP-Q, a CENPA-CAD centromere complex subunit AATF-Che1 PF13339.1 ETO31183.1 - 0.0022 18.1 8.0 0.0022 18.1 5.6 1.6 1 1 0 1 1 1 1 Apoptosis antagonizing transcription factor Spc7 PF08317.6 ETO31183.1 - 0.0022 16.6 13.4 0.0029 16.3 9.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Reo_sigmaC PF04582.7 ETO31183.1 - 0.0026 17.0 3.9 0.0034 16.6 2.7 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein IncA PF04156.9 ETO31183.1 - 0.0031 17.1 17.7 0.0049 16.4 12.2 1.3 1 0 0 1 1 1 1 IncA protein DUF2894 PF11445.3 ETO31183.1 - 0.0043 17.3 2.9 0.0045 17.2 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2894) CENP-F_leu_zip PF10473.4 ETO31183.1 - 0.017 14.9 17.8 0.026 14.3 12.3 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FUSC PF04632.7 ETO31183.1 - 0.02 13.3 1.2 0.023 13.1 0.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family FliJ PF02050.11 ETO31183.1 - 0.023 14.7 20.3 0.045 13.7 14.1 1.6 1 0 0 1 1 1 0 Flagellar FliJ protein ATG16 PF08614.6 ETO31183.1 - 0.028 14.2 18.2 0.08 12.7 12.6 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Phage_HK97_TLTM PF06120.6 ETO31183.1 - 0.034 13.4 8.8 0.047 13.0 6.1 1.1 1 0 0 1 1 1 0 Tail length tape measure protein DivIC PF04977.10 ETO31183.1 - 0.081 12.4 15.6 0.1 12.0 3.2 2.9 1 1 1 2 2 2 0 Septum formation initiator Glyco_hydro_63 PF03200.11 ETO31183.1 - 0.1 10.4 5.7 0.13 10.1 4.0 1.1 1 0 0 1 1 1 0 Mannosyl oligosaccharide glucosidase DUF4407 PF14362.1 ETO31183.1 - 0.11 11.4 7.4 0.16 10.8 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2252 PF10009.4 ETO31183.1 - 0.11 11.3 5.1 0.15 10.9 3.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Atg14 PF10186.4 ETO31183.1 - 0.25 10.2 16.0 0.47 9.3 11.1 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1664 PF07889.7 ETO31183.1 - 0.33 10.7 9.2 0.19 11.5 3.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CDC37_N PF03234.9 ETO31183.1 - 0.33 11.2 13.0 0.51 10.6 9.0 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding HIT PF01230.18 ETO31183.1 - 0.38 11.3 1.8 1.6 9.2 0.1 2.1 1 1 1 2 2 2 0 HIT domain TPR_MLP1_2 PF07926.7 ETO31183.1 - 0.41 10.4 21.0 3.7 7.2 13.3 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein EMP24_GP25L PF01105.19 ETO31183.1 - 1.1 8.9 9.4 2.8 7.6 6.5 1.7 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD POX PF07526.6 ETO31183.1 - 1.3 9.2 12.8 8.6 6.5 8.6 2.1 1 1 1 2 2 2 0 Associated with HOX DUF3573 PF12097.3 ETO31183.1 - 1.4 7.4 6.2 2 6.9 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF948 PF06103.6 ETO31183.1 - 4 7.3 10.0 1.8 8.4 3.2 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Tweety PF04906.8 ETO31183.1 - 4.5 5.5 9.8 5.7 5.2 1.1 2.0 1 1 1 2 2 2 0 Tweety DUF3972 PF13118.1 ETO31183.1 - 5.3 7.1 13.9 1.1 9.3 3.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3972) DUF342 PF03961.8 ETO31183.1 - 6.6 5.0 11.7 9.1 4.5 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF912 PF06024.7 ETO31183.1 - 7.4 6.6 9.1 2.2e+02 1.9 6.4 2.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) NPV_P10 PF05531.7 ETO31183.1 - 7.7 6.8 8.3 9.4 6.5 1.0 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Pentapeptide PF00805.17 ETO31185.1 - 1.2e-06 27.6 3.9 3.9e-06 25.9 2.2 2.1 1 1 1 2 2 2 2 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 ETO31185.1 - 8.3e-05 22.3 0.3 0.00014 21.6 0.2 1.4 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.1 ETO31185.1 - 8.5e-05 22.2 1.2 0.00023 20.9 0.8 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Omptin PF01278.15 ETO31185.1 - 0.0023 17.0 0.1 0.0035 16.4 0.1 1.3 1 0 0 1 1 1 1 Omptin family Ribosomal_L18_c PF14204.1 ETO31185.1 - 2.1 8.9 0.0 2.1 8.9 0.0 3.1 3 1 0 3 3 3 0 Ribosomal L18 C-terminal region Tubulin PF00091.20 ETO31186.1 - 1.3e-61 208.1 0.0 1.8e-61 207.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO31186.1 - 1.3e-26 93.0 0.0 2.2e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Kelch_6 PF13964.1 ETO31187.1 - 5.1e-06 26.4 0.1 0.0053 16.8 0.0 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 ETO31187.1 - 0.0017 18.0 2.6 0.015 15.0 0.0 2.4 2 1 0 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO31187.1 - 0.0048 16.4 0.1 0.39 10.3 0.0 2.2 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.10 ETO31187.1 - 0.027 14.2 0.1 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Kelch motif WD40 PF00400.27 ETO31188.1 - 2.9e-77 252.0 18.7 6.7e-14 51.1 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO31188.1 - 5.3e-12 45.8 0.3 7.9e-05 22.4 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO31188.1 - 8.6e-12 43.9 6.0 0.0051 15.0 0.1 5.2 1 1 4 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO31188.1 - 1.8e-11 43.4 9.3 0.012 14.4 0.4 5.2 1 1 4 5 5 5 5 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO31188.1 - 1.7e-07 29.8 0.1 9e-05 20.9 0.0 2.5 1 1 0 2 2 2 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO31188.1 - 7.2e-07 28.9 0.1 1.9e-05 24.2 0.0 2.6 1 1 1 2 2 2 1 PQQ-like domain DPPIV_N PF00930.16 ETO31188.1 - 1.1e-05 24.1 0.1 0.95 7.9 0.0 3.9 1 1 2 4 4 4 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF1258 PF06869.7 ETO31188.1 - 0.00021 20.5 2.4 5.9 5.8 0.0 4.2 1 1 4 5 5 5 1 Protein of unknown function (DUF1258) PD40 PF07676.7 ETO31188.1 - 0.00055 19.5 6.2 2.7 7.7 0.0 4.8 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO31188.1 - 0.00081 19.6 0.1 5 7.4 0.1 3.7 2 2 1 3 3 3 1 Resistin Hira PF07569.6 ETO31188.1 - 0.0031 16.7 0.4 2.4 7.3 0.0 4.1 3 1 2 5 5 5 1 TUP1-like enhancer of split B_lectin PF01453.19 ETO31188.1 - 0.017 15.0 0.4 0.099 12.5 0.0 2.3 2 1 0 2 2 2 0 D-mannose binding lectin Lactonase PF10282.4 ETO31188.1 - 0.039 13.0 0.0 3.6 6.5 0.0 2.3 1 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Nbas_N PF15492.1 ETO31188.1 - 0.045 12.8 1.2 2.6 7.0 0.1 3.1 1 1 3 4 4 4 0 Neuroblastoma-amplified sequence, N terminal WD40 PF00400.27 ETO31189.1 - 4.9e-37 124.4 14.1 1.1e-10 40.9 0.2 5.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO31189.1 - 9.1e-05 20.7 0.5 0.093 10.8 0.0 2.5 1 1 0 2 2 2 2 Nucleoporin Nup120/160 CAP_GLY PF01302.20 ETO31190.1 - 2.5e-108 353.8 38.1 2.7e-15 55.8 0.6 9.5 9 0 0 9 9 9 9 CAP-Gly domain Hint_2 PF13403.1 ETO31190.1 - 0.00041 20.2 1.2 15 5.4 0.0 5.6 7 0 0 7 7 7 2 Hint domain CAP_GLY PF01302.20 ETO31191.1 - 1.2e-69 229.9 24.2 2.9e-12 46.0 1.0 7.5 8 0 0 8 8 8 6 CAP-Gly domain SH3_2 PF07653.12 ETO31191.1 - 0.93 9.0 6.3 4.4 6.8 0.2 4.1 3 1 0 3 3 3 0 Variant SH3 domain V_ATPase_I PF01496.14 ETO31191.1 - 5.5 4.7 5.6 8.4 4.1 3.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1900 PF08954.6 ETO31192.1 - 3.5e-47 159.3 0.0 7.3e-47 158.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) WD40 PF00400.27 ETO31192.1 - 1.6e-16 59.5 0.1 4.6e-07 29.4 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat DivIC PF04977.10 ETO31192.1 - 0.13 11.7 0.5 0.46 10.0 0.4 1.9 1 0 0 1 1 1 0 Septum formation initiator HALZ PF02183.13 ETO31192.1 - 0.19 11.4 4.0 0.36 10.5 2.8 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF972 PF06156.8 ETO31192.1 - 0.33 11.3 3.8 0.67 10.3 2.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIVA PF05103.8 ETO31192.1 - 1.4 8.9 8.8 2.6 8.1 6.1 1.3 1 0 0 1 1 1 0 DivIVA protein DUF1899 PF08953.6 ETO31193.1 - 2.3e-15 55.9 0.0 3.9e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 ETO31193.1 - 0.00039 20.1 0.1 0.00075 19.2 0.1 1.4 1 0 0 1 1 1 1 WD domain, G-beta repeat NAD_binding_6 PF08030.7 ETO31196.1 - 6.8e-07 29.3 0.0 2.3e-06 27.6 0.0 1.7 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 ETO31196.1 - 0.006 17.1 0.2 0.095 13.2 0.0 2.4 1 1 1 2 2 2 1 Oxidoreductase NAD-binding domain Methyltransf_PK PF05891.7 ETO31197.1 - 0.077 12.2 0.1 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase PVL_ORF50 PF07768.6 ETO31198.1 - 0.065 13.2 8.9 0.11 12.5 6.2 1.4 1 0 0 1 1 1 0 PVL ORF-50-like family Macoilin PF09726.4 ETO31198.1 - 3.8 5.6 13.4 0.27 9.4 5.8 1.7 2 0 0 2 2 2 0 Transmembrane protein Phage_Gp23 PF10669.4 ETO31199.1 - 0.007 16.4 4.5 0.0083 16.2 3.1 1.1 1 0 0 1 1 1 1 Protein gp23 (Bacteriophage A118) Mem_trans PF03547.13 ETO31199.1 - 0.086 11.1 4.4 0.096 10.9 3.0 1.0 1 0 0 1 1 1 0 Membrane transport protein DUF1517 PF07466.6 ETO31200.1 - 0.067 12.1 0.2 0.067 12.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) PBP1_TM PF14812.1 ETO31200.1 - 0.092 13.0 0.4 0.092 13.0 0.3 5.2 3 1 1 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mucin PF01456.12 ETO31200.1 - 1.1 9.0 23.8 0.026 14.2 11.1 2.3 3 0 0 3 3 3 0 Mucin-like glycoprotein UPF0158 PF03682.8 ETO31201.1 - 0.044 13.3 2.1 0.064 12.8 0.4 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0158) DUF1777 PF08648.7 ETO31201.1 - 2.1 8.0 38.1 2.1 8.0 25.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) DUF3984 PF13136.1 ETO31201.1 - 4.9 6.2 36.7 1.2e+02 1.7 22.4 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF3984) DUF4551 PF15087.1 ETO31201.1 - 6.4 5.0 15.8 7.6 4.7 10.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Band_7 PF01145.20 ETO31202.1 - 2.7e-19 69.7 3.4 2.7e-19 69.7 2.3 1.5 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 ETO31202.1 - 0.0028 17.2 0.9 0.0064 16.0 0.2 1.8 1 1 1 2 2 2 1 SPFH domain-Band 7 family SporV_AA PF12164.3 ETO31202.1 - 0.11 12.4 1.7 0.35 10.8 0.1 2.2 2 0 0 2 2 2 0 Stage V sporulation protein AA E1-E2_ATPase PF00122.15 ETO31203.1 - 2.8 6.9 6.1 7.8 5.4 0.1 2.4 2 1 0 2 2 2 0 E1-E2 ATPase CBS PF00571.23 ETO31204.1 - 1.6e-08 34.2 0.0 3.3e-06 26.7 0.0 2.4 2 0 0 2 2 2 2 CBS domain RCSD PF05177.7 ETO31205.1 - 0.68 10.4 17.7 4.3 7.8 12.3 2.1 1 1 0 1 1 1 0 RCSD region Syntaxin PF00804.20 ETO31205.1 - 2.2 8.4 6.8 0.84 9.8 1.7 2.1 1 1 1 2 2 2 0 Syntaxin DnaJ PF00226.26 ETO31207.1 - 1.9e-18 65.9 2.7 4.6e-18 64.7 1.8 1.7 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.17 ETO31207.1 - 0.00084 18.9 0.0 0.0025 17.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO31207.1 - 0.0042 16.9 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO31207.1 - 0.098 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ATP-synt_ab_C PF00306.22 ETO31207.1 - 0.098 13.1 4.5 0.23 11.9 3.1 1.6 1 0 0 1 1 1 0 ATP synthase alpha/beta chain, C terminal domain SLA_LP_auto_ag PF05889.8 ETO31207.1 - 0.23 9.9 2.7 0.31 9.4 1.9 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) DUF2746 PF10874.3 ETO31207.1 - 0.7 10.1 4.1 0.58 10.3 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) Kelch_6 PF13964.1 ETO31209.1 - 3.1e-06 27.1 1.8 0.034 14.3 0.1 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO31209.1 - 7.9e-05 22.5 0.8 4.3 7.4 0.1 4.9 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO31209.1 - 0.00037 20.1 0.0 0.74 9.6 0.0 3.1 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO31209.1 - 0.00053 19.4 4.2 0.11 11.9 0.1 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO31209.1 - 0.0042 16.8 2.1 5.2 6.9 0.0 4.2 4 0 0 4 4 4 1 Kelch motif WD40 PF00400.27 ETO31210.1 - 5.6e-56 184.5 3.3 6.1e-14 51.2 0.0 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat eIF2A PF08662.6 ETO31210.1 - 2.3e-08 33.9 0.0 0.00054 19.7 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.4 ETO31210.1 - 2.7e-05 23.3 3.0 5.4 6.4 0.0 4.7 4 0 0 4 4 4 2 Proteasome subunit A N-terminal signature Nup160 PF11715.3 ETO31210.1 - 2.7e-05 22.5 0.2 0.4 8.7 0.0 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO31210.1 - 8.4e-05 21.0 0.2 0.45 8.7 0.0 2.7 1 1 2 3 3 3 3 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO31210.1 - 0.00049 19.6 0.1 0.01 15.3 0.0 2.6 1 1 1 2 2 2 1 PQQ-like domain SGL PF08450.7 ETO31210.1 - 0.00071 19.0 0.1 0.97 8.7 0.0 2.4 1 1 1 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 ETO31210.1 - 0.0011 18.9 0.0 11 6.1 0.0 3.6 2 1 2 4 4 4 0 Strictosidine synthase BBS2_Mid PF14783.1 ETO31210.1 - 0.0024 17.6 0.3 1.1 9.0 0.0 3.8 1 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region PD40 PF07676.7 ETO31210.1 - 0.0037 16.9 3.9 14 5.4 0.0 4.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat AcetylCoA_hyd_C PF13336.1 ETO31210.1 - 0.0069 16.0 0.4 24 4.5 0.0 3.8 3 1 1 4 4 4 0 Acetyl-CoA hydrolase/transferase C-terminal domain DUF4275 PF14101.1 ETO31210.1 - 0.013 15.6 0.0 1.6 8.7 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4275) Me-amine-dh_H PF06433.6 ETO31210.1 - 0.013 14.1 0.0 0.47 9.0 0.0 2.7 2 1 0 3 3 3 0 Methylamine dehydrogenase heavy chain (MADH) POT1 PF02765.12 ETO31210.1 - 0.026 14.4 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 Telomeric single stranded DNA binding POT1/CDC13 Arylsulfotran_2 PF14269.1 ETO31210.1 - 0.04 13.0 0.4 0.071 12.2 0.2 1.3 1 1 0 1 1 1 0 Arylsulfotransferase (ASST) FBD PF08387.5 ETO31210.1 - 0.12 11.8 0.0 3.1 7.3 0.0 2.4 2 0 0 2 2 2 0 FBD NtA PF03146.10 ETO31210.1 - 0.12 11.9 0.1 1.6 8.4 0.0 2.7 2 2 2 4 4 4 0 Agrin NtA domain PLD_C PF12357.3 ETO31210.1 - 0.15 11.6 0.1 1.4e+02 2.1 0.0 3.8 2 2 2 4 4 4 0 Phospholipase D C terminal DUF1903 PF08991.5 ETO31211.1 - 0.1 12.7 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) Bac_DnaA PF00308.13 ETO31214.1 - 0.042 13.4 1.2 2.6 7.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein DIL PF01843.14 ETO31215.1 - 0.47 10.3 4.8 2 8.3 0.0 4.1 5 0 0 5 5 5 0 DIL domain HCaRG PF07258.9 ETO31216.1 - 0.014 14.9 0.1 0.062 12.8 0.0 2.2 2 1 0 2 2 2 0 HCaRG protein Rep_fac_C PF08542.6 ETO31216.1 - 0.11 12.4 1.6 2.5 8.1 0.2 2.8 2 0 0 2 2 2 0 Replication factor C C-terminal domain DUF4363 PF14276.1 ETO31216.1 - 1.3 8.7 8.5 1.3 8.7 0.1 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4363) AAA PF00004.24 ETO31217.1 - 3e-07 30.7 0.1 6.6e-06 26.3 0.0 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 ETO31217.1 - 3.1e-06 27.9 1.2 0.037 14.8 0.1 4.3 3 1 0 3 3 3 1 AAA domain AAA_14 PF13173.1 ETO31217.1 - 5e-06 26.4 0.7 0.00054 19.8 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_5 PF07728.9 ETO31217.1 - 3e-05 23.7 0.0 0.00013 21.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 ETO31217.1 - 3.5e-05 24.1 0.2 0.0003 21.0 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_8 PF12780.2 ETO31217.1 - 8.8e-05 21.6 0.0 0.00019 20.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_22 PF13401.1 ETO31217.1 - 0.00053 20.1 0.0 0.019 15.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 ETO31217.1 - 0.026 14.4 0.0 0.09 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_3 PF07726.6 ETO31217.1 - 0.06 12.9 0.0 0.34 10.5 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 ETO31217.1 - 0.14 12.4 3.4 1.9 8.8 0.0 3.2 4 0 0 4 4 4 0 AAA domain Ecm29 PF13001.2 ETO31220.1 - 2.4e-06 26.3 0.1 3.3e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome stabiliser Complex1_LYR_1 PF13232.1 ETO31220.1 - 0.078 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Complex1_LYR-like Guanylate_kin PF00625.16 ETO31220.1 - 0.1 11.9 0.1 0.25 10.7 0.0 1.6 2 0 0 2 2 2 0 Guanylate kinase TBPIP PF07106.8 ETO31220.1 - 0.25 10.8 2.2 0.36 10.3 0.9 1.6 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TSA PF03249.8 ETO31221.1 - 0.11 10.9 0.6 0.12 10.8 0.4 1.0 1 0 0 1 1 1 0 Type specific antigen Cytochrom_C_asm PF01578.15 ETO31222.1 - 0.0073 15.8 11.2 0.022 14.2 7.8 1.6 1 1 0 1 1 1 1 Cytochrome C assembly protein AA_permease_2 PF13520.1 ETO31222.1 - 0.23 9.9 5.6 0.67 8.4 0.7 2.1 2 0 0 2 2 2 0 Amino acid permease Adeno_GP19K PF04881.8 ETO31223.1 - 0.016 14.9 0.4 0.019 14.7 0.3 1.0 1 0 0 1 1 1 0 Adenovirus GP19K XPA_N PF01286.13 ETO31223.1 - 1 9.0 2.9 2.3 7.9 0.0 2.6 3 0 0 3 3 3 0 XPA protein N-terminal ART PF01129.13 ETO31224.1 - 0.001 18.2 0.0 0.0021 17.2 0.0 1.5 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase YxiJ PF14176.1 ETO31225.1 - 0.011 15.8 1.2 0.038 14.1 0.4 1.9 1 1 1 2 2 2 0 YxiJ-like protein WD40 PF00400.27 ETO31226.1 - 8.4e-33 111.0 5.8 6.7e-11 41.6 0.2 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 ETO31226.1 - 8.2e-05 22.3 0.0 0.00057 19.6 0.0 2.3 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO31226.1 - 0.00047 19.7 1.2 2 8.1 0.0 3.7 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO31226.1 - 0.00078 18.3 0.2 0.44 9.2 0.1 2.1 1 1 1 2 2 2 2 Nup133 N terminal like Nup160 PF11715.3 ETO31226.1 - 0.016 13.3 0.0 0.03 12.4 0.0 1.5 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Lysyl_oxidase PF01186.12 ETO31226.1 - 0.053 13.1 0.1 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 Lysyl oxidase Resistin PF06954.6 ETO31226.1 - 0.056 13.7 0.6 6.3 7.1 0.0 3.1 1 1 2 3 3 3 0 Resistin PRK PF00485.13 ETO31227.1 - 2.4e-07 30.5 0.2 1.3e-06 28.0 0.1 2.2 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 ETO31227.1 - 8.8e-07 29.7 0.1 3e-06 28.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 ETO31227.1 - 3.1e-05 24.2 0.0 7.5e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 ABC transporter NB-ARC PF00931.17 ETO31227.1 - 8.7e-05 21.5 0.0 0.00026 19.9 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain KAP_NTPase PF07693.9 ETO31227.1 - 0.0003 19.9 0.1 0.00052 19.1 0.0 1.4 2 0 0 2 2 2 1 KAP family P-loop domain AAA_18 PF13238.1 ETO31227.1 - 0.00032 21.0 0.3 0.0013 19.0 0.0 2.3 2 1 1 3 3 2 1 AAA domain AAA_5 PF07728.9 ETO31227.1 - 0.00065 19.4 0.0 0.004 16.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF258 PF03193.11 ETO31227.1 - 0.001 18.2 0.0 0.002 17.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 ETO31227.1 - 0.0016 18.4 0.0 0.0039 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 ETO31227.1 - 0.0017 18.5 0.0 0.0088 16.1 0.0 2.2 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.1 ETO31227.1 - 0.0018 17.7 0.0 0.0034 16.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RNA_helicase PF00910.17 ETO31227.1 - 0.0051 16.9 0.2 0.029 14.5 0.0 2.4 2 0 0 2 2 2 1 RNA helicase 6PF2K PF01591.13 ETO31227.1 - 0.007 15.4 0.8 0.011 14.8 0.0 1.7 2 0 0 2 2 2 1 6-phosphofructo-2-kinase MMR_HSR1 PF01926.18 ETO31227.1 - 0.0074 16.2 0.0 0.018 14.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase ArgK PF03308.11 ETO31227.1 - 0.0077 15.0 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 ArgK protein MobB PF03205.9 ETO31227.1 - 0.021 14.5 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 ETO31227.1 - 0.068 12.8 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 NTPase GTP_EFTU PF00009.22 ETO31227.1 - 0.11 11.9 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 ETO31227.1 - 0.11 11.8 0.2 0.31 10.4 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain AAA_23 PF13476.1 ETO31227.1 - 0.16 12.2 11.0 0.013 15.8 3.0 2.1 1 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 ETO31227.1 - 0.17 11.7 2.3 1.2 9.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain SMC_N PF02463.14 ETO31227.1 - 0.27 10.4 1.1 0.57 9.3 0.1 1.9 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain Imm14 PF15428.1 ETO31228.1 - 0.046 14.1 2.8 0.059 13.7 0.0 2.5 3 1 0 3 3 3 0 Immunity protein 14 Baculo_11_kDa PF06143.6 ETO31229.1 - 0.018 14.4 4.6 0.37 10.1 0.1 3.4 3 0 0 3 3 3 0 Baculovirus 11 kDa family Mucin PF01456.12 ETO31229.1 - 0.12 12.1 26.8 0.44 10.3 18.6 1.9 1 0 0 1 1 1 0 Mucin-like glycoprotein ASD2 PF08687.6 ETO31229.1 - 3.1 7.0 11.5 0.084 12.1 1.0 2.3 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 Clathrin PF00637.15 ETO31230.1 - 4.8e-11 42.4 8.7 6.7e-07 29.0 0.3 3.1 4 0 0 4 4 4 2 Region in Clathrin and VPS Metallopep PF12044.3 ETO31231.1 - 0.013 14.0 1.7 0.015 13.7 1.2 1.1 1 0 0 1 1 1 0 Putative peptidase family COMPASS-Shg1 PF05205.7 ETO31231.1 - 1.1 9.5 7.5 7 7.0 0.5 2.2 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 DUF2345 PF10106.4 ETO31232.1 - 0.032 13.8 0.0 8 6.0 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2345) DUF2592 PF10766.4 ETO31232.1 - 0.12 11.7 2.8 27 4.1 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2592) Gal_Lectin PF02140.13 ETO31232.1 - 1.1 9.5 4.2 3.9 7.8 0.1 3.6 5 0 0 5 5 5 0 Galactose binding lectin domain WD40 PF00400.27 ETO31233.1 - 8.7e-182 583.3 45.7 2.3e-13 49.4 0.2 16.1 16 0 0 16 16 16 16 WD domain, G-beta repeat Nup160 PF11715.3 ETO31233.1 - 1.3e-13 49.9 37.7 0.2 9.7 0.0 13.1 2 2 10 13 13 13 7 Nucleoporin Nup120/160 DUF1258 PF06869.7 ETO31233.1 - 1.3e-06 27.6 5.5 2.2 7.2 0.0 6.3 4 3 4 8 8 8 3 Protein of unknown function (DUF1258) Cytochrom_D1 PF02239.11 ETO31233.1 - 1.1e-05 23.9 10.2 0.092 11.0 0.0 6.0 3 2 4 7 7 7 2 Cytochrome D1 heme domain Pentapeptide PF00805.17 ETO31233.1 - 1.1e-05 24.5 0.1 2.2e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Str_synth PF03088.11 ETO31233.1 - 0.00021 21.2 0.7 47 4.1 0.0 7.5 8 2 2 10 10 10 0 Strictosidine synthase Pentapeptide_4 PF13599.1 ETO31233.1 - 0.0013 18.4 0.5 0.0031 17.2 0.1 1.9 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) PD40 PF07676.7 ETO31233.1 - 0.007 16.0 18.6 12 5.6 0.1 8.6 9 0 0 9 9 9 0 WD40-like Beta Propeller Repeat Pentapeptide_3 PF13576.1 ETO31233.1 - 0.016 15.0 1.1 0.15 11.9 0.0 2.8 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) F420_ligase PF01996.11 ETO31233.1 - 0.052 12.6 0.1 6.4 5.7 0.0 4.0 4 1 0 4 4 4 0 F420-0:Gamma-glutamyl ligase BLUF PF04940.7 ETO31233.1 - 0.093 12.4 4.3 49 3.7 0.0 6.1 7 0 0 7 7 7 0 Sensors of blue-light using FAD Mid2 PF04478.7 ETO31233.1 - 0.12 11.7 19.5 7.9 5.8 0.1 9.1 4 3 7 12 12 12 0 Mid2 like cell wall stress sensor Resistin PF06954.6 ETO31233.1 - 0.14 12.4 2.8 1.5e+02 2.7 0.0 5.9 6 2 2 8 8 7 0 Resistin DUF1831 PF08866.5 ETO31235.1 - 0.38 11.0 6.3 0.089 13.0 0.9 2.4 2 2 0 2 2 2 0 Putative amino acid metabolism Spc24 PF08286.6 ETO31235.1 - 1.5 8.5 6.9 0.63 9.7 0.2 2.4 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Nuc_H_symport PF03825.11 ETO31236.1 - 4.9e-05 22.2 0.7 4.9e-05 22.2 0.5 1.6 1 1 0 1 1 1 1 Nucleoside H+ symporter MFS_1 PF07690.11 ETO31236.1 - 0.0029 16.4 23.0 0.04 12.6 16.1 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 ETO31236.1 - 0.0057 16.4 0.1 0.0057 16.4 0.0 2.7 3 1 1 4 4 4 1 MFS_1 like family DUF4231 PF14015.1 ETO31236.1 - 0.032 14.2 4.6 0.92 9.5 0.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) FA_desaturase PF00487.19 ETO31236.1 - 0.063 12.7 2.4 0.1 12.0 1.7 1.5 1 0 0 1 1 1 0 Fatty acid desaturase Cation_ATPase_N PF00690.21 ETO31236.1 - 0.11 11.9 2.8 12 5.4 0.1 3.4 3 0 0 3 3 3 0 Cation transporter/ATPase, N-terminus Nse4_C PF08743.5 ETO31237.1 - 0.28 11.2 3.2 0.26 11.3 0.4 2.3 2 0 0 2 2 2 0 Nse4 C-terminal Peptidase_S49_N PF08496.5 ETO31237.1 - 1 9.1 8.7 1.4 8.7 2.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal SRP9-21 PF05486.7 ETO31238.1 - 0.06 13.0 1.4 0.12 12.1 0.2 2.0 2 0 0 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) 4HBT_3 PF13622.1 ETO31238.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily GrpE PF01025.14 ETO31239.1 - 5.4e-39 133.3 10.0 2.5e-38 131.2 7.0 1.8 1 1 0 1 1 1 1 GrpE PRF PF06875.6 ETO31239.1 - 0.029 13.5 0.0 0.047 12.8 0.0 1.3 1 0 0 1 1 1 0 Plethodontid receptivity factor PRF LMBR1 PF04791.11 ETO31239.1 - 3.3 6.1 4.5 3.4 6.1 3.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein B56 PF01603.15 ETO31240.1 - 1.7e-84 283.7 10.1 2.2e-84 283.4 7.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF4116 PF13475.1 ETO31240.1 - 0.035 13.5 0.2 4.4 6.8 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) NfI_DNAbd_pre-N PF10524.4 ETO31241.1 - 0.044 13.3 0.1 0.11 12.1 0.1 1.7 1 0 0 1 1 1 0 Nuclear factor I protein pre-N-terminus Rrp15p PF07890.7 ETO31241.1 - 0.049 13.6 9.0 0.072 13.1 6.2 1.4 1 1 0 1 1 1 0 Rrp15p DUF4524 PF15025.1 ETO31241.1 - 0.087 12.3 1.2 0.13 11.7 0.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4524) Y_phosphatase2 PF03162.8 ETO31241.1 - 0.1 11.9 3.4 0.15 11.4 2.4 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Kri1_C PF12936.2 ETO31241.1 - 2.9 7.8 11.5 0.38 10.7 5.3 1.6 2 0 0 2 2 2 0 KRI1-like family C-terminal RNA_pol_Rpb1_5 PF04998.12 ETO31241.1 - 3.3 6.9 7.0 3.7 6.7 4.8 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 MRJP PF03022.11 ETO31242.1 - 1.6e-18 66.9 0.1 2.1e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Major royal jelly protein Corona_S2 PF01601.11 ETO31243.1 - 0.012 13.6 0.9 0.014 13.4 0.6 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Baculo_PEP_C PF04513.7 ETO31243.1 - 0.019 14.8 0.6 0.024 14.4 0.4 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2968 PF11180.3 ETO31243.1 - 0.022 14.1 1.6 0.028 13.8 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) OGG_N PF07934.7 ETO31243.1 - 0.039 13.9 0.4 0.046 13.6 0.3 1.3 1 0 0 1 1 1 0 8-oxoguanine DNA glycosylase, N-terminal domain RmuC PF02646.11 ETO31243.1 - 0.051 12.4 4.7 0.054 12.3 3.1 1.3 1 1 0 1 1 1 0 RmuC family Occludin_ELL PF07303.8 ETO31243.1 - 0.054 14.2 4.8 0.078 13.7 3.3 1.3 1 0 0 1 1 1 0 Occludin homology domain Arb2 PF09757.4 ETO31243.1 - 0.067 12.6 0.6 0.072 12.5 0.4 1.1 1 0 0 1 1 1 0 Arb2 domain Ribosomal_L17 PF01196.14 ETO31243.1 - 0.073 13.6 1.6 0.088 13.3 1.1 1.3 1 1 0 1 1 1 0 Ribosomal protein L17 Spc42p PF11544.3 ETO31243.1 - 0.13 12.1 6.2 0.13 12.2 3.4 1.6 1 1 1 2 2 2 0 Spindle pole body component Spc42p AATF-Che1 PF13339.1 ETO31243.1 - 0.16 12.1 5.1 0.19 11.8 3.6 1.2 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Allexi_40kDa PF05549.6 ETO31243.1 - 0.26 10.5 1.8 0.25 10.5 1.2 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Spc7 PF08317.6 ETO31243.1 - 0.44 9.1 9.5 0.51 8.9 6.6 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Fib_alpha PF08702.5 ETO31243.1 - 0.44 10.6 5.9 0.55 10.3 4.1 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CDC37_N PF03234.9 ETO31243.1 - 0.47 10.7 5.2 0.71 10.1 3.6 1.4 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding IncA PF04156.9 ETO31243.1 - 0.56 9.7 7.2 0.65 9.5 5.0 1.2 1 1 0 1 1 1 0 IncA protein V-ATPase_C PF03223.10 ETO31243.1 - 0.56 9.0 6.5 0.37 9.6 2.9 1.6 1 1 1 2 2 2 0 V-ATPase subunit C Fmp27_WPPW PF10359.4 ETO31243.1 - 1.3 7.3 7.9 1.4 7.2 5.5 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Mito_carr PF00153.22 ETO31247.1 - 2.3e-26 91.3 0.2 5.5e-12 45.2 0.0 2.0 1 1 1 2 2 2 2 Mitochondrial carrier protein Mito_carr PF00153.22 ETO31248.1 - 0.1 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial carrier protein XK-related PF09815.4 ETO31250.1 - 0.05 12.6 7.8 0.7 8.8 5.4 2.0 1 1 0 1 1 1 0 XK-related protein FKBP_N PF01346.13 ETO31253.1 - 0.013 15.5 5.8 0.015 15.3 3.6 1.4 1 1 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Microtub_bind PF13931.1 ETO31253.1 - 0.087 12.9 9.4 0.12 12.5 6.5 1.2 1 0 0 1 1 1 0 Kinesin-associated microtubule-binding DUF1948 PF09185.5 ETO31253.1 - 0.11 12.1 3.3 0.12 11.9 1.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1948) WD40 PF00400.27 ETO31254.1 - 2.3e-60 198.4 20.2 3.8e-11 42.4 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO31254.1 - 8.3e-07 27.5 1.3 0.71 7.9 0.0 4.9 2 1 3 5 5 5 4 Nucleoporin Nup120/160 WD40 PF00400.27 ETO31256.1 - 2e-106 344.4 42.3 1.3e-10 40.6 0.1 14.4 15 0 0 15 15 15 11 WD domain, G-beta repeat DUF2441 PF10386.4 ETO31256.1 - 0.003 17.6 0.2 2.1 8.3 0.0 4.2 2 2 1 4 4 4 1 Protein of unknown function (DUF2441) PD40 PF07676.7 ETO31256.1 - 0.6 9.8 10.0 76 3.1 0.0 6.0 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat DUF4550 PF15084.1 ETO31257.1 - 0.033 14.2 0.7 0.072 13.1 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4550) FANCI_HD1 PF14679.1 ETO31257.1 - 0.1 12.3 0.2 0.37 10.5 0.1 1.9 2 0 0 2 2 2 0 FANCI helical domain 1 PBP1_TM PF14812.1 ETO31258.1 - 0.018 15.3 1.0 0.035 14.3 0.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myc_N PF01056.13 ETO31258.1 - 0.025 13.7 0.4 0.037 13.2 0.2 1.2 1 0 0 1 1 1 0 Myc amino-terminal region PIG-U PF06728.8 ETO31258.1 - 0.11 11.3 5.1 1.3 7.7 3.5 2.0 1 1 0 1 1 1 0 GPI transamidase subunit PIG-U DM PF00751.13 ETO31259.1 - 0.17 11.4 7.4 0.16 11.4 3.5 2.2 2 0 0 2 2 2 0 DM DNA binding domain DUF3671 PF12420.3 ETO31260.1 - 7.8 6.5 9.6 3.8 7.5 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function WD40 PF00400.27 ETO31263.1 - 1.8e-49 163.8 32.0 3.8e-11 42.4 0.1 6.4 5 1 1 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO31263.1 - 6.2e-09 34.5 7.7 0.013 13.6 0.2 4.1 2 1 2 4 4 4 4 Nucleoporin Nup120/160 DUF2844 PF11005.3 ETO31263.1 - 0.2 11.4 0.0 0.37 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2844) Peptidase_S10 PF00450.17 ETO31264.1 - 7.3e-25 87.9 0.5 1.2e-24 87.2 0.3 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Nucleoplasmin PF03066.10 ETO31264.1 - 0.0071 15.8 7.6 0.01 15.3 5.3 1.3 1 0 0 1 1 1 1 Nucleoplasmin RNA_pol_3_Rpc31 PF11705.3 ETO31264.1 - 0.017 15.0 8.4 0.026 14.4 5.8 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 AF1Q PF15017.1 ETO31264.1 - 0.018 14.9 5.1 0.04 13.8 3.6 1.6 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator BSP_II PF05432.6 ETO31264.1 - 0.034 13.4 6.9 0.056 12.7 4.8 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF2457 PF10446.4 ETO31264.1 - 0.046 12.4 9.4 0.062 12.0 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 ETO31264.1 - 0.072 11.0 7.5 0.089 10.7 5.2 1.0 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 ETO31264.1 - 0.076 12.6 6.2 0.11 12.0 4.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.1 ETO31264.1 - 0.081 13.2 6.4 0.16 12.3 4.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.6 ETO31264.1 - 0.082 12.7 2.6 0.12 12.1 1.8 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Med17 PF10156.4 ETO31264.1 - 0.12 10.6 1.2 0.16 10.2 0.8 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex Daxx PF03344.10 ETO31264.1 - 0.13 10.6 4.2 0.15 10.5 2.9 1.1 1 0 0 1 1 1 0 Daxx Family DUF4484 PF14831.1 ETO31264.1 - 0.14 12.2 4.7 0.22 11.6 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) CENP-B_dimeris PF09026.5 ETO31264.1 - 0.23 11.7 18.7 0.66 10.2 12.9 1.8 1 1 1 2 2 2 0 Centromere protein B dimerisation domain NOA36 PF06524.7 ETO31264.1 - 0.27 10.4 5.4 0.36 10.0 3.7 1.2 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.6 ETO31264.1 - 0.33 8.7 2.2 0.43 8.3 1.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM176 PF14851.1 ETO31264.1 - 0.36 10.5 2.8 0.57 9.8 1.9 1.3 1 0 0 1 1 1 0 FAM176 family VID27 PF08553.5 ETO31264.1 - 0.48 8.5 4.7 0.58 8.3 3.2 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Myc_N PF01056.13 ETO31264.1 - 0.57 9.2 4.7 0.81 8.7 3.3 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Bd3614_N PF14442.1 ETO31264.1 - 0.71 9.8 4.2 1.5 8.8 2.9 1.5 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal CDC45 PF02724.9 ETO31264.1 - 1.7 6.5 5.1 2.4 6.0 3.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Dicty_REP PF05086.7 ETO31264.1 - 2.5 5.7 5.9 3 5.5 4.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DNA_pol_phi PF04931.8 ETO31264.1 - 3.8 5.1 16.1 4.9 4.7 11.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi WD40 PF00400.27 ETO31265.1 - 5.4e-73 238.4 21.0 9e-13 47.5 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO31265.1 - 1e-11 44.9 0.5 0.0008 19.1 0.0 3.5 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO31265.1 - 7.3e-09 34.3 0.5 0.044 12.0 0.0 4.0 1 1 3 4 4 4 3 Cytochrome D1 heme domain Nup160 PF11715.3 ETO31265.1 - 1.2e-06 27.0 8.4 0.14 10.3 0.0 4.8 1 1 3 4 4 4 3 Nucleoporin Nup120/160 PD40 PF07676.7 ETO31265.1 - 3.6e-06 26.5 7.8 0.069 12.8 0.1 5.7 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 ETO31265.1 - 4.4e-05 22.7 2.7 3.4 6.7 0.0 4.7 1 1 3 5 5 5 2 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 ETO31265.1 - 0.0024 17.1 11.8 3.1 7.2 0.0 6.3 7 0 0 7 7 7 2 Proteasome subunit A N-terminal signature Str_synth PF03088.11 ETO31265.1 - 0.013 15.5 3.4 8.5 6.4 0.0 4.5 3 2 2 5 5 5 0 Strictosidine synthase Hira PF07569.6 ETO31265.1 - 0.014 14.6 4.7 10 5.2 0.0 4.5 2 1 5 7 7 7 0 TUP1-like enhancer of split SGL PF08450.7 ETO31265.1 - 0.019 14.3 0.4 0.99 8.7 0.1 2.9 1 1 1 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region PQQ_2 PF13360.1 ETO31265.1 - 0.12 11.7 0.7 1.7 8.0 0.5 2.6 1 1 0 1 1 1 0 PQQ-like domain VIT1 PF01988.14 ETO31266.1 - 3e-30 105.3 0.1 3.8e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 VIT family MAF_flag10 PF01973.13 ETO31267.1 - 0.018 14.5 0.0 0.035 13.6 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF115 DUF3357 PF11837.3 ETO31268.1 - 0.076 12.8 0.0 0.13 12.1 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) Swi5 PF07061.6 ETO31269.1 - 2.5e-13 49.6 7.6 2.2e-12 46.6 5.2 2.2 1 1 0 1 1 1 1 Swi5 Band_3_cyto PF07565.8 ETO31269.1 - 0.088 12.3 4.6 0.12 11.8 3.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain YfhO PF09586.5 ETO31269.1 - 1.2 7.0 4.7 1.4 6.8 3.3 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO MIP-T3 PF10243.4 ETO31270.1 - 6.4e-05 21.6 16.4 6.4e-05 21.6 11.3 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Nop14 PF04147.7 ETO31270.1 - 2.3 6.0 29.3 3.5 5.4 20.3 1.2 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 ETO31270.1 - 7.6 4.8 30.7 0.21 10.0 17.0 1.4 2 0 0 2 2 2 0 Daxx Family HECT PF00632.20 ETO31271.1 - 3e-11 43.0 0.2 4.4e-11 42.5 0.2 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SAPS PF04499.10 ETO31271.1 - 1.8 7.1 8.7 2.3 6.7 6.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MIP-T3 PF10243.4 ETO31271.1 - 1.8 6.9 33.7 2.2 6.6 23.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Asp-B-Hydro_N PF05279.6 ETO31271.1 - 2.2 8.0 30.6 3.1 7.5 21.2 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CDC45 PF02724.9 ETO31272.1 - 0.0042 15.1 3.9 0.0044 15.1 2.7 1.1 1 0 0 1 1 1 1 CDC45-like protein Mem_trans PF03547.13 ETO31272.1 - 0.024 12.9 0.9 0.03 12.6 0.6 1.1 1 0 0 1 1 1 0 Membrane transport protein Tim54 PF11711.3 ETO31272.1 - 0.035 12.7 0.5 0.042 12.4 0.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SR-25 PF10500.4 ETO31272.1 - 0.27 10.6 22.8 0.45 9.9 15.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BUD22 PF09073.5 ETO31272.1 - 0.32 9.9 17.3 0.42 9.6 12.0 1.2 1 0 0 1 1 1 0 BUD22 TFIIF_alpha PF05793.7 ETO31272.1 - 2.6 6.2 23.4 3.3 5.9 16.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FLO_LFY PF01698.11 ETO31272.1 - 2.9 6.6 10.3 3.9 6.2 7.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein THRAP3_BCLAF1 PF15440.1 ETO31272.1 - 3.5 6.1 21.9 4.8 5.7 15.2 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family MIP-T3 PF10243.4 ETO31272.1 - 3.9 5.8 13.7 4.8 5.5 9.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 FAM176 PF14851.1 ETO31272.1 - 4.1 7.0 12.5 19 4.9 6.6 2.5 2 0 0 2 2 2 0 FAM176 family Sporozoite_P67 PF05642.6 ETO31272.1 - 4.2 5.0 13.8 5.4 4.7 9.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2101 PF09874.4 ETO31273.1 - 0.88 9.0 4.3 0.97 8.8 3.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) PDR_CDR PF06422.7 ETO31273.1 - 0.93 9.1 3.4 0.82 9.3 1.7 1.4 1 1 0 1 1 1 0 CDR ABC transporter DBB PF14545.1 ETO31274.1 - 0.00066 19.2 0.0 0.00096 18.6 0.0 1.2 1 0 0 1 1 1 1 Dof, BCAP, and BANK (DBB) motif, AMO PF02461.11 ETO31274.1 - 0.034 13.8 0.3 0.057 13.1 0.2 1.3 1 0 0 1 1 1 0 Ammonia monooxygenase MAPEG PF01124.13 ETO31274.1 - 0.075 12.6 0.4 13 5.3 0.0 2.7 3 0 0 3 3 3 0 MAPEG family DUF4064 PF13273.1 ETO31274.1 - 0.81 9.8 4.9 1.7 8.7 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) ATPase_gene1 PF09527.5 ETO31274.1 - 6.8 6.5 6.2 0.77 9.6 0.4 2.2 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) Pkinase PF00069.20 ETO31275.1 - 2.5e-21 75.9 0.0 3.5e-20 72.2 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO31275.1 - 6.3e-08 31.9 0.2 2.1e-05 23.7 0.0 2.7 2 1 1 3 3 3 2 Protein tyrosine kinase Kdo PF06293.9 ETO31275.1 - 0.0021 17.1 0.0 0.0035 16.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MukE PF04288.8 ETO31275.1 - 0.007 15.1 0.1 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 MukE-like family Pkinase PF00069.20 ETO31276.1 - 0.00039 19.6 0.6 0.00068 18.8 0.1 1.6 2 0 0 2 2 2 1 Protein kinase domain NCKAP5 PF15246.1 ETO31276.1 - 0.074 12.4 2.8 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 Nck-associated protein 5, Peripheral clock protein DUF4618 PF15397.1 ETO31277.1 - 0.0055 16.0 22.1 0.14 11.4 3.8 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4618) Syntaxin_2 PF14523.1 ETO31277.1 - 0.0057 16.6 16.7 0.0057 16.6 11.6 1.9 2 0 0 2 2 2 1 Syntaxin-like protein MAD PF05557.8 ETO31277.1 - 0.012 13.7 27.8 0.015 13.4 19.3 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein FUSC PF04632.7 ETO31277.1 - 0.019 13.4 1.6 0.021 13.2 1.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Prominin PF05478.6 ETO31277.1 - 0.076 10.5 10.2 0.1 10.1 7.1 1.1 1 0 0 1 1 1 0 Prominin Filament PF00038.16 ETO31277.1 - 0.16 11.4 24.3 0.16 11.4 14.6 1.8 1 1 0 1 1 1 0 Intermediate filament protein V_ATPase_I PF01496.14 ETO31277.1 - 0.5 8.1 12.9 0.57 7.9 8.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Borrelia_P83 PF05262.6 ETO31277.1 - 0.8 7.8 21.0 0.97 7.6 14.6 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein ApoO PF09769.4 ETO31277.1 - 1.1 8.9 6.5 1.7 8.3 4.4 1.5 1 1 0 1 1 1 0 Apolipoprotein O UvrD-helicase PF00580.16 ETO31277.1 - 1.1 8.4 14.1 1.5 7.9 9.7 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF2730 PF10805.3 ETO31277.1 - 1.3 8.7 10.8 2.9 7.6 7.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) Tmemb_cc2 PF10267.4 ETO31277.1 - 1.6 7.1 20.1 2.2 6.7 13.9 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Laminin_II PF06009.7 ETO31277.1 - 2.2 8.0 14.7 1.6 8.5 8.6 1.8 1 1 1 2 2 2 0 Laminin Domain II DUF4613 PF15390.1 ETO31277.1 - 4.1 5.4 13.5 5.2 5.1 9.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) IncA PF04156.9 ETO31277.1 - 4.9 6.7 30.6 15 5.1 21.2 1.8 1 1 0 1 1 1 0 IncA protein DUF1539 PF07560.6 ETO31277.1 - 5.4 6.8 12.0 3.4 7.5 7.0 1.6 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1539) DUF2317 PF10079.4 ETO31277.1 - 6.9 5.1 21.0 1.2 7.7 11.6 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2317) Z1 PF10593.4 ETO31277.1 - 8.6 5.5 12.8 5.2 6.2 7.6 1.4 1 1 0 1 1 1 0 Z1 domain RE_Alw26IDE PF09665.5 ETO31277.1 - 8.9 4.8 13.8 11 4.5 9.5 1.3 1 1 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) IFT57 PF10498.4 ETO31277.1 - 9.2 4.8 25.4 15 4.2 17.5 1.4 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Bestrophin PF01062.16 ETO31277.1 - 9.4 5.0 7.9 12 4.6 0.3 2.0 1 1 1 2 2 2 0 Bestrophin, RFP-TM, chloride channel EST1 PF10374.4 ETO31278.1 - 0.047 13.6 0.7 0.054 13.4 0.5 1.2 1 0 0 1 1 1 0 Telomerase activating protein Est1 DUF943 PF06092.7 ETO31278.1 - 5.2 6.3 10.6 0.9 8.8 3.3 2.2 1 1 2 3 3 3 0 Enterobacterial putative membrane protein (DUF943) DUF3889 PF13028.1 ETO31279.1 - 0.021 14.4 0.0 0.046 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3889) DUF3832 PF12909.2 ETO31279.1 - 0.085 12.9 0.3 0.14 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3832) Rep_fac_C PF08542.6 ETO31280.1 - 3.8e-13 49.2 0.1 2.5e-08 33.7 0.0 2.9 3 0 0 3 3 3 2 Replication factor C C-terminal domain AAA PF00004.24 ETO31280.1 - 2e-11 44.1 0.0 3.5e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 ETO31280.1 - 2.3e-08 33.1 0.1 3.1e-06 26.1 0.0 2.7 2 1 1 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 ETO31280.1 - 9.4e-08 32.2 0.0 4.1e-07 30.1 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain DNA_pol3_delta2 PF13177.1 ETO31280.1 - 3.3e-06 26.8 1.7 3.4e-05 23.5 1.1 2.7 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 ETO31280.1 - 3.4e-06 26.9 0.0 6.6e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 ETO31280.1 - 2.5e-05 23.4 0.0 5.4e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 ETO31280.1 - 2.8e-05 23.7 0.0 8.2e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 ETO31280.1 - 4.1e-05 22.8 0.0 8e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 ETO31280.1 - 0.00012 21.6 0.0 0.0057 16.1 0.0 2.6 1 1 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 ETO31280.1 - 0.00014 22.0 1.9 0.048 13.8 0.1 3.1 1 1 2 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 ETO31280.1 - 0.00034 20.1 0.0 0.00058 19.3 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_11 PF13086.1 ETO31280.1 - 0.0018 17.9 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETO31280.1 - 0.0031 17.8 0.0 0.0063 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 ETO31280.1 - 0.0036 16.1 0.0 0.0077 15.0 0.0 1.6 1 0 0 1 1 1 1 ArgK protein Viral_helicase1 PF01443.13 ETO31280.1 - 0.0038 16.7 0.0 0.0062 16.0 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 ETO31280.1 - 0.018 14.5 0.4 0.085 12.3 0.2 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase NTPase_1 PF03266.10 ETO31280.1 - 0.024 14.3 0.2 0.099 12.3 0.1 2.2 1 1 0 1 1 1 0 NTPase AAA_3 PF07726.6 ETO31280.1 - 0.024 14.2 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 ETO31280.1 - 0.026 14.0 0.1 0.086 12.3 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.22 ETO31280.1 - 0.035 14.4 0.1 0.085 13.1 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 ETO31280.1 - 0.046 13.6 0.0 0.089 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 ETO31280.1 - 0.06 14.1 0.1 0.11 13.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 ETO31280.1 - 0.079 11.8 0.0 0.17 10.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.9 ETO31280.1 - 0.088 12.5 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 ETO31280.1 - 0.095 11.6 0.1 0.49 9.3 0.1 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 ETO31280.1 - 0.098 12.8 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 ETO31280.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 ETO31280.1 - 0.13 12.0 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 ETO31280.1 - 0.13 11.9 0.0 0.27 10.8 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase AAA_23 PF13476.1 ETO31280.1 - 0.14 12.4 0.3 0.29 11.4 0.2 1.6 1 1 0 1 1 1 0 AAA domain UPF0560 PF10577.4 ETO31281.1 - 0.026 12.7 10.8 0.034 12.4 7.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 SDA1 PF05285.7 ETO31281.1 - 0.084 12.1 39.3 0.11 11.7 27.3 1.1 1 0 0 1 1 1 0 SDA1 Ycf1 PF05758.7 ETO31281.1 - 0.22 9.1 24.6 0.37 8.4 17.0 1.4 1 0 0 1 1 1 0 Ycf1 Neur_chan_memb PF02932.11 ETO31281.1 - 0.91 9.3 10.9 1.6 8.5 7.5 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1510 PF07423.6 ETO31281.1 - 1.6 8.0 44.6 0.054 12.8 26.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1510) SAPS PF04499.10 ETO31281.1 - 1.6 7.2 19.3 2.2 6.8 13.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Proteasome PF00227.21 ETO31282.1 - 6.1e-43 146.3 1.7 2.3e-23 82.4 0.0 3.1 3 0 0 3 3 3 3 Proteasome subunit MARVEL PF01284.18 ETO31282.1 - 0.0054 16.5 1.8 0.0083 15.9 1.2 1.3 1 0 0 1 1 1 1 Membrane-associating domain GPI2 PF06432.6 ETO31282.1 - 0.19 11.0 4.6 0.045 13.0 1.1 1.4 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase Vma12 PF11712.3 ETO31284.1 - 0.41 10.3 6.3 1.5 8.5 4.3 2.0 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Peptidase_S49_N PF08496.5 ETO31284.1 - 3.4 7.4 12.8 22 4.8 7.1 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal STAS PF01740.16 ETO31286.1 - 1.5e-20 72.7 0.1 2.5e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 STAS domain Sulfate_transp PF00916.15 ETO31286.1 - 9.2e-14 51.1 1.2 1.5e-13 50.4 0.8 1.3 1 0 0 1 1 1 1 Sulfate transporter family B-block_TFIIIC PF04182.7 ETO31287.1 - 2.3e-10 40.1 0.6 1.8e-07 30.9 0.0 3.7 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC z-alpha PF02295.12 ETO31287.1 - 8.4e-05 22.2 0.1 0.93 9.3 0.0 3.7 3 0 0 3 3 3 2 Adenosine deaminase z-alpha domain IF2_N PF04760.10 ETO31287.1 - 0.007 15.9 0.2 0.045 13.4 0.0 2.5 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region DUF3791 PF12668.2 ETO31287.1 - 0.0086 15.6 0.0 0.066 12.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3791) MarR_2 PF12802.2 ETO31287.1 - 0.11 12.1 0.0 0.68 9.6 0.0 2.1 2 0 0 2 2 2 0 MarR family Spc42p PF11544.3 ETO31288.1 - 0.0069 16.2 3.6 0.0069 16.2 2.5 5.8 5 2 0 5 5 5 2 Spindle pole body component Spc42p Peptidase_C12 PF01088.16 ETO31289.1 - 2.7e-37 128.0 0.2 3.2e-37 127.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 IL31 PF15209.1 ETO31289.1 - 0.06 12.9 0.2 0.098 12.2 0.1 1.3 1 0 0 1 1 1 0 Interleukin 31 RPAP2_Rtr1 PF04181.8 ETO31289.1 - 0.13 12.3 3.7 0.14 12.2 0.2 2.1 2 0 0 2 2 2 0 Rtr1/RPAP2 family WD40 PF00400.27 ETO31290.1 - 1.4e-65 214.9 26.5 2e-12 46.4 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO31290.1 - 9.1e-10 37.2 8.0 0.011 13.9 0.1 5.0 2 2 3 5 5 5 5 Nucleoporin Nup120/160 NAD_Gly3P_dh_N PF01210.18 ETO31290.1 - 0.17 11.6 0.4 1.7 8.3 0.0 2.7 4 0 0 4 4 4 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pro_racemase PF05544.6 ETO31291.1 - 2.3e-14 52.9 0.0 2.8e-14 52.6 0.0 1.0 1 0 0 1 1 1 1 Proline racemase Mnd1 PF03962.10 ETO31292.1 - 0.84 9.2 9.8 1.7 8.2 6.0 2.1 2 1 0 2 2 2 0 Mnd1 family zf-B_box PF00643.19 ETO31292.1 - 3.6 7.5 17.7 0.056 13.3 6.7 2.2 2 0 0 2 2 2 0 B-box zinc finger DUF325 PF03804.8 ETO31293.1 - 0.0049 16.5 0.2 0.95 9.2 0.0 2.4 2 0 0 2 2 2 2 Viral domain of unknown function Methyltransf_16 PF10294.4 ETO31293.1 - 0.009 15.4 0.4 0.016 14.6 0.3 1.5 1 0 0 1 1 1 1 Putative methyltransferase Ustilago_mating PF05722.7 ETO31293.1 - 0.091 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Ustilago B locus mating-type protein DUF3091 PF11291.3 ETO31294.1 - 0.028 14.3 1.2 0.073 13.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3091) bZIP_2 PF07716.10 ETO31295.1 - 0.1 12.4 0.3 0.21 11.4 0.2 1.5 1 0 0 1 1 1 0 Basic region leucine zipper MAT1 PF06391.8 ETO31297.1 - 0.0014 18.2 1.0 0.0014 18.2 0.7 1.8 2 0 0 2 2 2 1 CDK-activating kinase assembly factor MAT1 DUF853 PF05872.7 ETO31297.1 - 0.055 11.8 2.1 0.073 11.4 1.5 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Mucin PF01456.12 ETO31297.1 - 0.15 11.8 22.3 0.072 12.8 7.1 2.6 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3439 PF11921.3 ETO31297.1 - 5.3 6.8 17.5 0.047 13.4 4.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) WD40 PF00400.27 ETO31298.1 - 2.5e-06 27.1 5.4 0.16 11.8 0.6 4.2 3 1 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO31298.1 - 0.0049 15.0 0.1 0.0096 14.1 0.0 1.6 1 1 0 1 1 1 1 Nucleoporin Nup120/160 2OG-FeII_Oxy_3 PF13640.1 ETO31301.1 - 5.4e-13 49.3 0.0 1.1e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 ETO31301.1 - 1.6e-05 24.4 0.1 3.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Oxygenase-NA PF09859.4 ETO31301.1 - 4.6e-05 22.7 0.0 9.6e-05 21.7 0.0 1.6 1 1 0 1 1 1 1 Oxygenase, catalysing oxidative methylation of damaged DNA 2OG-FeII_Oxy PF03171.15 ETO31301.1 - 0.012 15.9 0.1 0.044 14.0 0.1 2.0 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.1 ETO31301.1 - 0.012 15.8 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase TauD PF02668.11 ETO31301.1 - 0.041 13.5 0.2 0.28 10.8 0.0 1.9 1 1 1 2 2 2 0 Taurine catabolism dioxygenase TauD, TfdA family DUF771 PF05595.6 ETO31301.1 - 0.062 13.2 2.4 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF771) DUF3270 PF11674.3 ETO31301.1 - 7.4 6.6 8.1 24 5.0 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) Ras PF00071.17 ETO31302.1 - 2.7e-28 98.4 1.3 5.7e-17 61.5 0.0 2.2 1 1 0 2 2 2 2 Ras family Miro PF08477.8 ETO31302.1 - 7.4e-12 45.8 0.3 1.2e-10 41.8 0.2 2.1 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO31302.1 - 1.4e-05 24.4 0.0 0.0057 15.9 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETO31302.1 - 0.008 15.3 1.3 0.1 11.7 0.9 2.1 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 ETO31302.1 - 0.0095 15.8 0.2 0.054 13.4 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase R3H PF01424.17 ETO31303.1 - 1.1e-08 34.6 0.1 1.1e-08 34.6 0.1 2.1 2 0 0 2 2 2 1 R3H domain DUF3437 PF11919.3 ETO31304.1 - 0.19 11.4 2.2 1 9.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) DUF912 PF06024.7 ETO31305.1 - 4.1 7.4 8.3 0.19 11.8 0.9 2.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3995 PF13160.1 ETO31306.1 - 2.7 8.0 6.1 1.7 8.7 1.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3995) zf-C2HC5 PF06221.8 ETO31307.1 - 8.1e-15 54.3 8.7 1.5e-14 53.4 6.0 1.5 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type ASCH PF04266.9 ETO31307.1 - 1.3e-10 41.5 0.1 4.8e-10 39.7 0.0 2.0 2 1 0 2 2 2 1 ASCH domain Beta-Casp PF10996.3 ETO31307.1 - 0.09 12.7 0.1 0.22 11.4 0.1 1.7 1 0 0 1 1 1 0 Beta-Casp domain zinc_ribbon_2 PF13240.1 ETO31307.1 - 0.23 10.9 6.2 0.66 9.5 4.3 1.9 1 0 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 ETO31307.1 - 0.81 8.9 5.9 3.1 7.1 4.0 2.1 1 1 0 1 1 1 0 zinc-ribbon domain ubiquitin PF00240.18 ETO31308.1 - 3.6e-10 39.1 0.0 6.6e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 ETO31308.1 - 9e-06 25.2 0.1 1.7e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 ETO31308.1 - 0.033 14.4 0.1 0.056 13.7 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain NKAIN PF05640.9 ETO31308.1 - 0.75 8.7 13.1 0.7 8.8 8.2 1.5 1 1 0 1 1 1 0 Na,K-Atpase Interacting protein F_actin_cap_B PF01115.12 ETO31309.1 - 0.025 13.7 1.6 0.037 13.2 1.1 1.2 1 0 0 1 1 1 0 F-actin capping protein, beta subunit IncA PF04156.9 ETO31310.1 - 0.01 15.4 7.9 0.01 15.4 5.5 4.4 2 1 2 4 4 4 0 IncA protein Jnk-SapK_ap_N PF09744.4 ETO31310.1 - 0.014 15.3 16.2 0.014 15.3 11.2 3.6 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 DUF3250 PF11618.3 ETO31310.1 - 0.021 15.0 0.2 0.052 13.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3250) PspA_IM30 PF04012.7 ETO31310.1 - 7.4 5.8 30.8 0.19 11.0 6.5 3.2 2 2 1 3 3 3 0 PspA/IM30 family DUF544 PF04424.8 ETO31311.1 - 8e-17 61.1 0.7 1.3e-15 57.3 0.1 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF544) DUF843 PF05814.6 ETO31313.1 - 0.024 14.4 0.1 0.056 13.2 0.1 1.6 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) DUSP PF06337.7 ETO31313.1 - 0.029 14.7 0.3 0.15 12.4 0.0 2.0 2 0 0 2 2 2 0 DUSP domain SAM_1 PF00536.25 ETO31314.1 - 0.0024 18.0 0.1 2.4 8.3 0.0 3.0 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) NACHT PF05729.7 ETO31315.1 - 4.8e-17 62.1 0.0 3.5e-16 59.3 0.0 2.2 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETO31315.1 - 5.6e-05 23.2 0.0 0.00017 21.6 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 ETO31315.1 - 0.0045 17.1 0.3 0.027 14.5 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETO31315.1 - 0.0053 16.4 0.0 0.0099 15.6 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain DAP3 PF10236.4 ETO31315.1 - 0.0057 15.6 0.1 0.018 14.0 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 NB-ARC PF00931.17 ETO31315.1 - 0.0066 15.3 0.0 0.048 12.5 0.0 2.3 3 0 0 3 3 3 1 NB-ARC domain Torsin PF06309.6 ETO31315.1 - 0.0078 16.0 0.0 0.027 14.3 0.0 1.9 2 0 0 2 2 2 1 Torsin AAA_18 PF13238.1 ETO31315.1 - 0.048 13.9 0.0 0.048 13.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain DUF1251 PF06856.6 ETO31315.1 - 0.085 12.3 0.1 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1251) Nucleoplasmin PF03066.10 ETO31315.1 - 2.7 7.5 23.0 0.17 11.4 9.7 2.4 2 0 0 2 2 2 0 Nucleoplasmin Sporozoite_P67 PF05642.6 ETO31315.1 - 9.6 3.9 6.2 15 3.2 4.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PIG-U PF06728.8 ETO31316.1 - 0.0042 16.0 1.2 0.0051 15.7 0.9 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U DUF2198 PF09964.4 ETO31316.1 - 0.024 14.3 0.5 0.079 12.7 0.0 2.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2198) FokI_N PF02981.10 ETO31316.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease FokI, recognition domain HEAT_2 PF13646.1 ETO31317.1 - 3.5e-07 30.4 0.0 0.0096 16.1 0.0 2.5 2 1 0 2 2 2 2 HEAT repeats DUF3826 PF12875.2 ETO31317.1 - 0.01 15.5 0.4 0.86 9.2 0.0 2.9 2 2 1 4 4 4 0 Protein of unknown function (DUF3826) HEAT_EZ PF13513.1 ETO31317.1 - 0.022 15.2 0.1 12 6.4 0.0 3.6 3 1 2 5 5 5 0 HEAT-like repeat TIP120 PF08623.5 ETO31317.1 - 0.14 11.7 3.5 2.5 7.6 0.0 2.6 1 1 2 3 3 3 0 TATA-binding protein interacting (TIP20) Ank_2 PF12796.2 ETO31318.1 - 1.1e-08 35.2 0.2 6.9e-08 32.7 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO31318.1 - 6.1e-08 32.1 0.4 0.00098 19.1 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 ETO31318.1 - 3.7e-06 26.4 0.0 0.00042 19.9 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 ETO31318.1 - 1.8e-05 24.8 0.3 9.3e-05 22.5 0.2 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO31318.1 - 4.2e-05 23.9 0.2 0.00017 21.9 0.1 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) HEAT PF02985.17 ETO31318.1 - 0.00029 20.6 0.0 0.0096 15.9 0.0 3.0 2 0 0 2 2 2 1 HEAT repeat HEAT_2 PF13646.1 ETO31318.1 - 0.00042 20.5 0.0 0.0039 17.4 0.0 2.4 1 1 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.1 ETO31318.1 - 0.02 15.4 0.0 0.069 13.6 0.0 2.0 1 0 0 1 1 1 0 HEAT-like repeat TPR_11 PF13414.1 ETO31319.1 - 6.2e-07 28.9 0.6 1.3e-06 27.9 0.4 1.5 1 0 0 1 1 1 1 TPR repeat TPR_12 PF13424.1 ETO31319.1 - 4.9e-06 26.3 1.9 0.0046 16.8 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO31319.1 - 0.00027 20.8 0.1 0.0088 16.1 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO31319.1 - 0.00039 20.1 0.5 0.95 9.5 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO31319.1 - 0.003 18.2 1.3 0.0099 16.5 0.3 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO31319.1 - 0.0034 16.9 1.1 1.5 8.5 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO31319.1 - 0.049 13.4 0.3 20 5.2 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETO31319.1 - 0.12 12.7 0.3 0.12 12.7 0.2 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETO31319.1 - 0.2 12.3 1.1 24 5.9 0.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 ETO31323.1 - 1.2e-23 82.4 5.4 6.4e-10 38.5 0.0 5.2 3 1 2 5 5 5 5 TPR repeat TPR_2 PF07719.12 ETO31323.1 - 6e-23 78.8 8.9 0.00099 18.8 0.0 8.0 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.1 ETO31323.1 - 1.8e-20 72.6 5.6 3.6e-06 26.8 0.2 5.8 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.23 ETO31323.1 - 1.3e-19 68.8 15.2 0.00089 18.7 0.0 7.2 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 ETO31323.1 - 3.9e-17 61.1 0.0 3.3e-05 24.1 0.0 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO31323.1 - 1.4e-15 57.4 0.0 0.00021 21.8 0.0 5.4 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO31323.1 - 1e-12 46.8 0.6 0.0053 16.4 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETO31323.1 - 1.9e-12 47.3 0.3 0.062 13.6 0.1 6.0 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO31323.1 - 1.5e-10 40.4 7.6 0.00063 19.7 0.0 6.9 6 0 0 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO31323.1 - 7.3e-10 38.8 17.4 0.0018 18.3 0.3 5.8 4 2 3 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETO31323.1 - 9e-10 38.3 0.9 0.033 14.6 0.1 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO31323.1 - 1.6e-07 31.0 1.5 0.69 9.9 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETO31323.1 - 2e-06 27.5 0.2 0.45 10.3 0.0 4.7 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO31323.1 - 1.2e-05 24.7 3.8 4.5 7.3 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO31323.1 - 4.6e-05 23.2 0.0 1 9.2 0.0 4.6 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat PPR_2 PF13041.1 ETO31324.1 - 1.5e-15 56.8 5.1 2.5e-08 33.7 0.4 3.7 2 1 1 3 3 3 3 PPR repeat family PPR PF01535.15 ETO31324.1 - 3.4e-14 51.7 7.8 0.0019 18.0 0.1 4.7 4 0 0 4 4 4 4 PPR repeat PPR_3 PF13812.1 ETO31324.1 - 3.5e-11 42.4 0.0 0.0059 16.7 0.0 4.5 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 ETO31324.1 - 0.00012 21.4 0.3 1.3 8.5 0.0 3.3 3 0 0 3 3 3 2 PPR repeat DUF3636 PF12331.3 ETO31324.1 - 0.013 15.0 0.2 0.031 13.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3636) zf-TRAF PF02176.13 ETO31325.1 - 6.5e-06 26.4 0.3 6.5e-06 26.4 0.2 2.8 3 1 0 3 3 3 1 TRAF-type zinc finger zf-RING_2 PF13639.1 ETO31325.1 - 0.089 12.6 2.2 0.22 11.3 0.7 2.3 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.1 ETO31325.1 - 0.22 11.5 5.1 0.75 9.8 1.5 3.1 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) NblA PF04485.7 ETO31325.1 - 1.3 8.9 4.2 8.7 6.3 0.2 3.4 4 0 0 4 4 4 0 Phycobilisome degradation protein nblA zf-P11 PF03854.9 ETO31325.1 - 5.7 6.4 9.2 0.84 9.1 0.1 3.1 3 0 0 3 3 3 0 P-11 zinc finger ECH PF00378.15 ETO31326.1 - 1.3e-58 198.0 0.2 1.6e-58 197.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 ETO31326.1 - 0.048 13.4 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Peptidase family S49 PTPlike_phytase PF14566.1 ETO31327.1 - 9.5e-26 90.6 0.1 9.5e-26 90.6 0.1 2.4 2 1 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 ETO31327.1 - 0.01 16.1 0.4 0.034 14.3 0.0 2.1 1 1 1 2 2 2 1 Tyrosine phosphatase family SSP160 PF06933.6 ETO31327.1 - 1.6 6.5 19.7 2.4 6.0 13.6 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.12 ETO31327.1 - 2.4 7.9 29.1 4.5 7.0 20.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein 7tm_3 PF00003.17 ETO31328.1 - 2e-09 37.1 34.2 2.7e-09 36.7 23.7 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR PufQ PF05398.6 ETO31329.1 - 0.077 13.0 0.1 0.25 11.3 0.0 1.9 1 0 0 1 1 1 0 PufQ cytochrome subunit TMEM154 PF15102.1 ETO31329.1 - 0.082 12.6 3.5 1.7 8.3 2.6 2.9 2 1 0 2 2 2 0 TMEM154 protein family DDHD PF02862.12 ETO31329.1 - 0.13 12.0 11.1 0.23 11.2 5.9 2.1 2 0 0 2 2 2 0 DDHD domain RAM PF15320.1 ETO31330.1 - 0.1 12.8 7.1 0.16 12.2 4.9 1.3 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein Herpes_DNAp_acc PF04929.7 ETO31330.1 - 0.16 10.8 6.1 0.2 10.6 4.2 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Menin PF05053.8 ETO31330.1 - 0.31 9.1 13.1 0.37 8.9 9.1 1.0 1 0 0 1 1 1 0 Menin DUF3438 PF11920.3 ETO31330.1 - 0.93 8.2 3.8 1.3 7.8 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) NRDE-2 PF08424.5 ETO31330.1 - 5.5 5.7 10.9 7.1 5.4 7.6 1.2 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference CaM_binding PF07839.6 ETO31330.1 - 9.8 6.4 12.3 22 5.3 8.6 1.7 1 1 0 1 1 1 0 Plant calmodulin-binding domain Transket_pyr PF02779.19 ETO31331.1 - 2.1e-53 180.4 0.0 3.2e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 ETO31331.1 - 1.6e-48 165.0 0.2 2.1e-48 164.5 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Cpn60_TCP1 PF00118.19 ETO31332.1 - 4.8e-63 213.4 5.4 6.2e-63 213.0 3.8 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PPO1_KFDV PF12143.3 ETO31332.1 - 0.041 13.7 0.1 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF_B2219) TPR_11 PF13414.1 ETO31333.1 - 1.3e-07 31.1 5.6 3.9e-05 23.2 0.1 4.1 5 0 0 5 5 5 1 TPR repeat TPR_2 PF07719.12 ETO31333.1 - 3.4e-07 29.6 4.0 0.0029 17.3 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat NARP1 PF12569.3 ETO31333.1 - 4.2e-07 29.1 5.9 4.7e-05 22.3 0.3 2.6 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_16 PF13432.1 ETO31333.1 - 1.1e-05 25.9 2.7 1.1 10.0 0.0 4.4 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO31333.1 - 1.2e-05 24.7 1.0 0.63 9.9 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO31333.1 - 5e-05 23.1 0.7 0.019 14.8 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO31333.1 - 0.00055 19.4 4.5 0.022 14.3 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO31333.1 - 0.0015 18.9 0.8 21 6.0 0.0 4.7 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO31333.1 - 0.0017 18.6 2.5 16 6.2 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETO31333.1 - 0.024 14.9 7.1 2.4 8.5 0.0 4.1 4 2 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 ETO31333.1 - 0.031 14.4 1.9 15 6.0 0.0 4.6 6 0 0 6 6 5 0 Tetratricopeptide repeat Metallophos PF00149.23 ETO31334.1 - 0.046 13.1 1.7 0.082 12.2 1.2 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase PIG-P PF08510.7 ETO31334.1 - 0.18 11.4 0.0 0.18 11.4 0.0 2.3 3 0 0 3 3 3 0 PIG-P PP2C PF00481.16 ETO31335.1 - 1.3e-33 116.4 3.7 1.9e-26 93.0 0.3 2.5 1 1 1 2 2 2 2 Protein phosphatase 2C DUF2146 PF10220.4 ETO31335.1 - 0.0062 14.5 3.3 0.0085 14.1 2.3 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2146) Nucleoplasmin PF03066.10 ETO31335.1 - 0.0075 15.7 4.2 0.013 14.9 2.9 1.3 1 0 0 1 1 1 1 Nucleoplasmin Pox_Ag35 PF03286.9 ETO31335.1 - 0.064 12.7 9.6 0.12 11.9 6.6 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SpoIIE PF07228.7 ETO31335.1 - 0.073 12.7 0.0 0.32 10.6 0.0 2.0 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) FAM176 PF14851.1 ETO31335.1 - 0.17 11.5 4.2 0.29 10.7 2.9 1.4 1 0 0 1 1 1 0 FAM176 family TRAP_alpha PF03896.11 ETO31335.1 - 0.23 10.4 4.6 0.36 9.7 3.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PWWP PF00855.12 ETO31335.1 - 0.66 10.2 0.0 0.66 10.2 0.0 2.2 1 1 1 2 2 2 0 PWWP domain DUF2363 PF10155.4 ETO31336.1 - 0.003 17.4 2.4 0.025 14.5 0.5 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2363) Endonuclease_NS PF01223.18 ETO31336.1 - 0.078 12.5 1.4 0.11 12.0 0.1 1.7 2 1 0 2 2 2 0 DNA/RNA non-specific endonuclease NACHT PF05729.7 ETO31338.1 - 0.0066 16.1 0.1 0.014 15.0 0.0 1.5 2 0 0 2 2 2 1 NACHT domain HAUS6_N PF14661.1 ETO31338.1 - 0.31 10.3 5.1 0.43 9.8 3.5 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Exonuc_VII_L PF02601.10 ETO31338.1 - 4.4 6.4 9.0 10 5.1 6.2 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit ATP-synt_E PF05680.7 ETO31338.1 - 7.1 6.6 6.9 2.7 8.0 1.2 2.2 2 0 0 2 2 2 0 ATP synthase E chain FDF PF09532.5 ETO31339.1 - 0.35 11.4 17.7 0.36 11.3 12.3 1.0 1 0 0 1 1 1 0 FDF domain SspB PF04386.8 ETO31339.1 - 4.6 6.8 6.5 4.8 6.7 4.5 1.0 1 0 0 1 1 1 0 Stringent starvation protein B MRP-S26 PF14943.1 ETO31339.1 - 5.4 6.5 19.9 5.6 6.4 13.8 1.0 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 VWA PF00092.23 ETO31340.1 - 1.5 8.5 5.6 1.6 8.3 3.9 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain CDC45 PF02724.9 ETO31341.1 - 2.1 6.3 26.4 2.3 6.1 18.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.6 ETO31341.1 - 3 6.7 38.1 3 6.7 26.4 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PRP21_like_P PF12230.3 ETO31341.1 - 8.7 5.7 30.2 10 5.5 20.9 1.0 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein Acetyltransf_7 PF13508.1 ETO31342.1 - 1.1e-09 38.2 1.4 1.1e-09 38.2 1.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETO31342.1 - 4.6e-08 32.9 0.1 6.5e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 ETO31342.1 - 0.0042 16.8 0.0 0.0065 16.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 ETO31342.1 - 0.018 14.9 0.7 0.16 11.8 0.1 2.0 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETO31342.1 - 0.052 13.4 0.0 0.12 12.2 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Hairy_orange PF07527.8 ETO31342.1 - 0.28 10.9 0.0 0.28 10.9 0.0 1.9 2 0 0 2 2 2 0 Hairy Orange Adeno_E3_CR2 PF02439.10 ETO31342.1 - 1.3 8.5 8.8 2.2 7.8 6.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Adaptin_N PF01602.15 ETO31343.1 - 2.4e-54 184.5 3.0 2.9e-54 184.3 2.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.17 ETO31343.1 - 6.8e-09 35.0 0.9 0.48 10.6 0.0 4.8 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.1 ETO31343.1 - 8.3e-09 35.6 0.2 0.00021 21.4 0.1 3.2 2 1 1 3 3 3 2 HEAT repeats Cnd1 PF12717.2 ETO31343.1 - 1.6e-07 31.3 2.7 1.7e-06 27.9 0.1 2.4 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 ETO31343.1 - 0.18 12.3 1.5 2.5 8.6 0.5 2.9 1 1 1 2 2 2 0 HEAT-like repeat Ipi1_N PF12333.3 ETO31343.1 - 1.3 9.0 4.4 2.4 8.1 0.1 3.1 3 1 1 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation NUDIX_4 PF14815.1 ETO31344.1 - 1.2e-10 40.7 0.1 2.6e-10 39.7 0.1 1.6 1 1 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.20 ETO31345.1 - 1.2e-14 54.5 0.1 5.2e-06 26.7 0.0 2.5 2 0 0 2 2 2 2 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 ETO31345.1 - 0.0002 20.9 0.0 0.00051 19.6 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 ETO31345.1 - 0.00038 20.5 6.3 0.00086 19.3 4.3 1.7 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III Corona_nucleoca PF00937.13 ETO31345.1 - 0.038 12.9 5.7 0.059 12.3 3.9 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF2201_N PF13203.1 ETO31345.1 - 0.24 10.5 2.6 0.41 9.7 1.8 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF3919 PF13057.1 ETO31345.1 - 0.44 9.9 12.2 0.43 10.0 7.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3919) F_actin_cap_B PF01115.12 ETO31346.1 - 2.6e-09 36.6 0.5 1.2e-08 34.4 0.3 1.8 1 1 0 1 1 1 1 F-actin capping protein, beta subunit DUF3310 PF11753.3 ETO31347.1 - 0.064 13.2 4.1 1.3 9.0 0.1 3.6 4 0 0 4 4 4 0 Protein of unknwon function (DUF3310) PI3_PI4_kinase PF00454.22 ETO31349.1 - 1.2e-09 37.9 0.0 3.9e-09 36.3 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase AMP-binding PF00501.23 ETO31349.1 - 0.23 9.8 0.0 0.43 8.9 0.0 1.4 1 0 0 1 1 1 0 AMP-binding enzyme WD40 PF00400.27 ETO31350.1 - 1.7e-05 24.4 6.5 0.0013 18.4 0.3 4.1 3 1 1 4 4 4 2 WD domain, G-beta repeat MMR_HSR1 PF01926.18 ETO31352.1 - 3.9e-05 23.5 0.1 0.0004 20.3 0.0 2.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 ETO31352.1 - 0.0003 20.0 2.8 0.0014 17.7 0.3 3.4 2 1 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 ETO31352.1 - 0.00074 19.8 0.1 0.00074 19.8 0.1 3.8 3 1 0 3 3 3 1 ABC transporter AAA_29 PF13555.1 ETO31352.1 - 0.0096 15.4 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 ETO31352.1 - 0.099 12.6 0.1 5.8 6.8 0.0 3.2 2 0 0 2 2 2 0 AAA ATPase domain PT PF04886.7 ETO31353.1 - 4.7e-77 252.9 322.6 3.6e-05 22.9 14.8 19.1 1 1 7 8 8 8 4 PT repeat Med31 PF05669.7 ETO31354.1 - 0.012 15.3 0.0 0.034 13.8 0.0 1.7 1 0 0 1 1 1 0 SOH1 DUF3490 PF11995.3 ETO31354.1 - 0.021 14.3 0.0 0.06 12.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) Archease PF01951.11 ETO31355.1 - 0.00023 21.1 0.5 0.38 10.6 0.0 2.5 1 1 1 2 2 2 2 Archease protein family (MTH1598/TM1083) GPS PF01825.16 ETO31355.1 - 0.0015 18.5 2.8 0.0044 17.0 1.9 1.8 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain DUF3497 PF12003.3 ETO31355.1 - 0.0069 15.7 0.4 0.014 14.7 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3497) PT-VENN PF04829.8 ETO31356.1 - 0.00035 20.0 0.3 0.0013 18.2 0.2 1.9 1 0 0 1 1 1 1 Pre-toxin domain with VENN motif Mem_trans PF03547.13 ETO31356.1 - 0.015 13.6 0.1 0.015 13.6 0.0 2.1 2 0 0 2 2 2 0 Membrane transport protein DUF1189 PF06691.6 ETO31356.1 - 0.073 12.3 1.0 1.9 7.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1189) DUF3382 PF11862.3 ETO31356.1 - 0.094 12.6 1.5 6.8 6.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) WD40 PF00400.27 ETO31357.1 - 5.2e-57 187.8 7.8 4.7e-13 48.4 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO31357.1 - 1.2e-09 38.2 0.8 1.4e-05 24.8 0.0 3.0 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO31357.1 - 6.6e-07 28.8 0.9 0.38 10.4 0.0 4.7 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO31357.1 - 2.8e-06 25.7 6.1 0.25 9.4 0.0 4.9 1 1 4 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO31357.1 - 0.0001 21.1 7.5 0.017 13.8 0.2 4.0 1 1 2 4 4 4 2 Nup133 N terminal like SGL PF08450.7 ETO31357.1 - 0.019 14.3 0.1 0.91 8.8 0.0 3.1 1 1 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region DPPIV_N PF00930.16 ETO31357.1 - 0.034 12.7 0.2 6.7 5.1 0.0 3.7 2 1 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region UCH PF00443.24 ETO31358.1 - 1.2e-06 27.8 0.0 1.6e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO31358.1 - 3.3e-05 23.4 0.0 3.7e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Retinal PF15449.1 ETO31359.1 - 0.031 11.9 34.7 0.013 13.1 13.4 2.1 1 1 1 2 2 2 0 Retinal protein CesA PF11439.3 ETO31359.1 - 0.096 12.6 0.1 6.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Type III secretion system filament chaperone CesA DUF11 PF01345.13 ETO31359.1 - 0.17 11.9 4.8 5.3 7.1 0.2 3.0 2 1 1 3 3 3 0 Domain of unknown function DUF11 Phage_HK97_TLTM PF06120.6 ETO31360.1 - 0.006 15.9 4.3 0.89 8.8 0.9 2.1 1 1 1 2 2 2 2 Tail length tape measure protein Peroxin-3 PF04882.7 ETO31360.1 - 0.009 14.7 1.0 0.011 14.4 0.7 1.1 1 0 0 1 1 1 1 Peroxin-3 LRRC37AB_C PF14914.1 ETO31360.1 - 0.08 12.3 1.3 0.11 11.9 0.9 1.2 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain SNARE PF05739.14 ETO31360.1 - 0.14 11.8 2.1 0.71 9.5 0.7 2.4 1 1 1 2 2 2 0 SNARE domain Prok-TraM PF09228.5 ETO31360.1 - 0.16 12.1 1.2 0.31 11.2 0.5 1.8 1 1 1 2 2 2 0 Prokaryotic Transcriptional repressor TraM DUF2422 PF10337.4 ETO31360.1 - 0.34 9.6 2.3 0.72 8.5 1.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2422) SYCE1 PF15233.1 ETO31360.1 - 0.39 10.6 9.0 0.3 10.9 5.0 1.6 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 Uds1 PF15456.1 ETO31360.1 - 0.68 9.9 5.8 11 6.0 4.0 2.1 1 1 0 1 1 1 0 Up-regulated During Septation DUF1664 PF07889.7 ETO31360.1 - 1.5 8.6 7.4 0.51 10.1 2.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CaM_binding PF07839.6 ETO31360.1 - 2 8.6 8.2 1.5 9.0 4.2 1.7 1 1 1 2 2 2 0 Plant calmodulin-binding domain Tweety PF04906.8 ETO31361.1 - 4.2e-06 25.4 5.2 9.4e-06 24.2 3.6 1.5 1 0 0 1 1 1 1 Tweety DUF4064 PF13273.1 ETO31361.1 - 0.12 12.4 0.2 0.3 11.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) LMBR1 PF04791.11 ETO31362.1 - 3.4e-22 78.6 9.5 1.2e-12 47.1 2.5 2.4 3 0 0 3 3 3 2 LMBR1-like membrane protein RXT2_N PF08595.6 ETO31362.1 - 0.0058 16.4 6.7 0.013 15.2 4.7 1.6 1 0 0 1 1 1 1 RXT2-like, N-terminal BORA_N PF15280.1 ETO31362.1 - 0.011 15.0 3.6 0.011 15.0 2.5 2.3 2 1 0 2 2 2 0 Protein aurora borealis N-terminus NOA36 PF06524.7 ETO31362.1 - 0.028 13.7 2.3 0.046 12.9 1.6 1.3 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.5 ETO31362.1 - 0.048 13.9 5.5 0.12 12.6 3.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 ETO31362.1 - 0.22 11.0 8.0 0.47 9.9 5.6 1.6 1 0 0 1 1 1 0 Nucleoplasmin Astro_capsid PF03115.9 ETO31362.1 - 3.3 5.8 9.6 0.073 11.3 2.0 1.6 2 0 0 2 2 2 0 Astrovirus capsid protein precursor EphA2_TM PF14575.1 ETO31363.1 - 0.0017 18.7 0.0 0.0036 17.6 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain FAM176 PF14851.1 ETO31363.1 - 0.0017 18.0 0.1 0.0026 17.4 0.0 1.2 1 0 0 1 1 1 1 FAM176 family Sarcoglycan_2 PF05510.8 ETO31363.1 - 0.0025 16.1 0.1 0.0033 15.7 0.0 1.1 1 0 0 1 1 1 1 Sarcoglycan alpha/epsilon IncA PF04156.9 ETO31363.1 - 0.006 16.2 0.0 0.0083 15.7 0.0 1.1 1 0 0 1 1 1 1 IncA protein TMEM51 PF15345.1 ETO31363.1 - 0.02 14.5 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 FAM163 PF15069.1 ETO31363.1 - 0.03 14.8 0.2 0.063 13.8 0.1 1.6 2 0 0 2 2 2 0 FAM163 family DUF1191 PF06697.7 ETO31363.1 - 0.081 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Homez PF11569.3 ETO31364.1 - 0.0095 14.9 1.0 0.017 14.1 0.1 1.8 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez KSR1-SAM PF13543.1 ETO31364.1 - 0.1 12.3 0.8 0.14 11.9 0.6 1.2 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 NDUF_B6 PF09782.4 ETO31364.1 - 0.13 12.1 0.1 0.22 11.3 0.0 1.4 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit RNA_pol_Rpb2_6 PF00562.23 ETO31366.1 - 1.1e-37 129.7 0.0 1.3e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.15 ETO31366.1 - 8.5e-27 93.2 0.2 1.5e-26 92.4 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 SNARE PF05739.14 ETO31368.1 - 1.4e-10 40.7 7.6 1.4e-10 40.7 5.3 2.2 2 0 0 2 2 2 1 SNARE domain FlaC_arch PF05377.6 ETO31368.1 - 0.087 12.7 0.6 0.087 12.7 0.4 2.8 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF948 PF06103.6 ETO31368.1 - 0.49 10.3 6.0 2.7 7.9 1.2 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) PIN_2 PF10130.4 ETO31368.1 - 2.8 7.9 5.8 0.38 10.8 0.5 2.1 2 1 1 3 3 3 0 PIN domain NPV_P10 PF05531.7 ETO31368.1 - 7 6.9 10.4 0.45 10.7 2.5 2.5 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein RGS PF00615.14 ETO31369.1 - 0.034 14.2 1.4 0.054 13.5 0.4 1.7 2 0 0 2 2 2 0 Regulator of G protein signaling domain RGS PF00615.14 ETO31371.1 - 0.014 15.4 1.1 1 9.4 0.2 2.6 1 1 1 2 2 2 0 Regulator of G protein signaling domain Zip PF02535.17 ETO31372.1 - 0.00066 18.7 1.1 0.00092 18.2 0.8 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2422 PF10337.4 ETO31372.1 - 0.043 12.6 0.4 0.058 12.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) RP-C_C PF11800.3 ETO31372.1 - 0.15 11.7 1.5 0.21 11.2 1.0 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region SelP_N PF04592.9 ETO31372.1 - 0.29 10.4 9.4 0.44 9.8 6.5 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RNA_pol_Rpb2_6 PF00562.23 ETO31373.1 - 5e-89 298.7 0.0 8.2e-89 298.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_2 PF04561.9 ETO31373.1 - 2.5e-34 118.3 0.1 6.2e-34 117.0 0.1 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_1 PF04563.10 ETO31373.1 - 1.5e-33 115.4 0.0 2.1e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 ETO31373.1 - 1.3e-20 72.9 0.0 2.7e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 ETO31373.1 - 1.2e-18 66.6 0.0 2.8e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 ETO31373.1 - 1.4e-17 63.4 0.6 3.2e-17 62.2 0.4 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 zf-RING_2 PF13639.1 ETO31374.1 - 9.6e-05 22.1 11.8 9.6e-05 22.1 8.2 1.7 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 ETO31374.1 - 0.0064 16.5 11.2 0.011 15.8 7.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 ETO31374.1 - 0.0099 15.7 5.3 0.018 14.8 3.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 ETO31374.1 - 0.026 14.1 6.1 0.026 14.1 4.2 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zinc_ribbon_5 PF13719.1 ETO31374.1 - 0.046 13.3 0.3 0.046 13.3 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 ETO31374.1 - 0.064 12.9 0.3 0.064 12.9 0.2 2.0 2 0 0 2 2 2 0 zinc-ribbon domain VESA1_N PF12785.2 ETO31374.1 - 0.08 11.9 5.7 0.099 11.5 3.9 1.1 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 Nucleoplasmin PF03066.10 ETO31374.1 - 0.14 11.6 2.9 0.14 11.6 0.6 1.9 2 0 0 2 2 2 0 Nucleoplasmin zf-RING_5 PF14634.1 ETO31374.1 - 3.7 7.3 16.7 12 5.7 10.2 2.3 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 ETO31374.1 - 8 6.2 12.6 17 5.2 8.8 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Strumpellin PF10266.4 ETO31375.1 - 6.6e-50 169.5 0.3 7.3e-50 169.4 0.2 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin DUF4441 PF14536.1 ETO31375.1 - 0.035 14.0 1.6 0.11 12.4 1.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4441) Pkinase PF00069.20 ETO31376.1 - 3.3e-23 82.1 0.2 1.7e-22 79.8 0.2 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO31376.1 - 0.00024 20.2 0.0 0.0011 18.1 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase TSGP1 PF07771.6 ETO31376.1 - 0.16 11.8 5.3 0.34 10.7 3.7 1.5 1 0 0 1 1 1 0 Tick salivary peptide group 1 DUF1201 PF06716.6 ETO31376.1 - 1 9.2 7.4 2.5 7.9 2.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1201) Strumpellin PF10266.4 ETO31378.1 - 6.8e-30 103.2 0.1 7.7e-30 103.1 0.0 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin EF-hand_1 PF00036.27 ETO31379.1 - 1.5e-05 23.9 0.4 3.8e-05 22.6 0.3 1.8 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 ETO31379.1 - 8.5e-05 22.0 0.5 0.00017 21.1 0.3 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO31379.1 - 0.00089 18.9 0.4 0.0021 17.7 0.3 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 ETO31379.1 - 0.0022 18.0 0.1 0.0051 16.9 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 ETO31379.1 - 0.0031 16.7 0.2 0.0076 15.5 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_4 PF12763.2 ETO31379.1 - 0.021 14.5 0.4 0.027 14.2 0.3 1.3 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Phostensin_N PF13916.1 ETO31379.1 - 0.092 12.7 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal WD40 PF00400.27 ETO31380.1 - 1.2e-52 173.9 18.6 1.2e-10 40.8 0.1 8.2 8 0 0 8 8 8 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO31380.1 - 1.4e-08 33.3 5.8 0.011 13.9 0.1 5.0 2 2 2 5 5 5 4 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO31380.1 - 8.1e-06 26.1 1.1 2.7e-05 24.4 0.8 2.0 1 0 0 1 1 1 1 TRAF-type zinc finger POLO_box PF00659.13 ETO31380.1 - 0.57 10.1 4.5 1.7 8.6 0.8 2.8 2 0 0 2 2 2 0 POLO box duplicated region DUF730 PF05325.6 ETO31380.1 - 7.4 6.4 10.3 17 5.2 0.6 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF730) Adaptin_N PF01602.15 ETO31381.1 - 2e-113 379.5 12.4 2.3e-113 379.2 8.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 ETO31381.1 - 0.0028 17.8 2.5 5.3 7.3 0.1 4.5 2 2 1 3 3 3 1 HEAT repeats HEAT PF02985.17 ETO31381.1 - 0.044 13.8 0.7 32 4.9 0.1 3.6 3 0 0 3 3 3 0 HEAT repeat LicD PF04991.8 ETO31382.1 - 0.0046 17.0 1.5 0.0051 16.9 1.1 1.3 1 0 0 1 1 1 1 LicD family BLVR PF06375.6 ETO31382.1 - 0.0099 15.7 5.0 0.016 14.9 3.5 1.4 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) Peptidase_S49_N PF08496.5 ETO31382.1 - 0.2 11.4 7.0 0.39 10.5 4.9 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SART-1 PF03343.8 ETO31382.1 - 0.53 8.5 11.2 0.67 8.2 7.8 1.1 1 0 0 1 1 1 0 SART-1 family SR-25 PF10500.4 ETO31382.1 - 0.74 9.2 11.4 1.1 8.6 7.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein G10 PF01125.12 ETO31382.1 - 2.6 7.5 10.5 0.15 11.6 1.8 2.3 1 1 1 2 2 2 0 G10 protein Pro_racemase PF05544.6 ETO31383.1 - 2.3e-45 154.8 0.1 7.1e-15 54.6 0.0 3.9 2 1 1 3 3 3 3 Proline racemase TSC22 PF01166.13 ETO31383.1 - 0.0055 16.6 0.5 0.01 15.7 0.3 1.4 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF706 PF05153.10 ETO31384.1 - 2.7e-29 102.2 2.6 3.1e-29 102.0 1.8 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) DUF3959 PF13105.1 ETO31384.1 - 0.56 9.4 5.8 0.62 9.3 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Peptidase_S49_N PF08496.5 ETO31384.1 - 6.4 6.5 7.4 9.3 6.0 5.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal VWA PF00092.23 ETO31385.1 - 1.2e-05 25.1 0.8 0.0066 16.1 0.2 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain Kazal_2 PF07648.10 ETO31385.1 - 3.3e-05 23.7 2.9 3.3e-05 23.7 2.0 3.0 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 ETO31385.1 - 0.0052 16.7 9.5 0.0052 16.7 6.6 3.9 3 1 0 3 3 3 1 Kazal-type serine protease inhibitor domain DUF3987 PF13148.1 ETO31385.1 - 0.12 10.8 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Rad60-SLD PF11976.3 ETO31386.1 - 0.076 12.7 0.1 0.26 10.9 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like RasGEF_N PF00618.15 ETO31387.1 - 0.0056 16.7 0.9 0.012 15.7 0.6 1.6 1 1 0 1 1 1 1 RasGEF N-terminal motif RIH_assoc PF08454.6 ETO31387.1 - 0.062 12.9 2.2 0.48 10.0 0.2 2.2 2 0 0 2 2 2 0 RyR and IP3R Homology associated DUF4162 PF13732.1 ETO31387.1 - 0.081 13.4 0.8 0.081 13.4 0.5 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4162) RabGAP-TBC PF00566.13 ETO31388.1 - 2.6e-11 43.4 2.0 2.6e-11 43.4 1.4 2.5 2 1 0 2 2 2 1 Rab-GTPase-TBC domain DUF2833 PF11090.3 ETO31388.1 - 0.13 12.4 0.7 0.3 11.2 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2833) AF-4 PF05110.8 ETO31389.1 - 0.011 13.6 14.1 0.011 13.6 9.8 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Macoilin PF09726.4 ETO31389.1 - 3.5 5.7 12.5 3.8 5.6 8.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Ion_trans PF00520.26 ETO31390.1 - 2.1e-09 36.9 0.4 2.1e-09 36.9 0.3 1.8 1 1 1 2 2 2 1 Ion transport protein Ion_trans PF00520.26 ETO31391.1 - 8.9e-20 70.7 3.9 1.1e-19 70.4 2.7 1.1 1 0 0 1 1 1 1 Ion transport protein DUF2975 PF11188.3 ETO31391.1 - 2.3 7.9 6.0 0.11 12.1 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) SAM_2 PF07647.12 ETO31392.1 - 0.01 15.6 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Apc15p PF05841.6 ETO31392.1 - 0.15 12.7 1.2 0.27 11.9 0.8 1.4 1 0 0 1 1 1 0 Apc15p protein WD40 PF00400.27 ETO31393.1 - 5.5e-18 64.1 9.4 2.2e-07 30.5 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat eIF2A PF08662.6 ETO31393.1 - 2.9e-06 27.1 1.1 0.0016 18.1 0.1 2.8 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A zf-UBR PF02207.15 ETO31395.1 - 1.6e-12 46.9 13.2 1.6e-12 46.9 9.2 3.9 4 1 1 5 5 5 1 Putative zinc finger in N-recognin (UBR box) ETRAMP PF09716.5 ETO31395.1 - 0.0011 18.8 0.0 0.56 10.2 0.0 2.7 2 1 0 2 2 2 2 Malarial early transcribed membrane protein (ETRAMP) Actin PF00022.14 ETO31396.1 - 2.2e-121 404.9 0.0 2.9e-121 404.6 0.0 1.1 1 0 0 1 1 1 1 Actin ESSS PF10183.4 ETO31396.1 - 0.13 12.6 0.0 0.35 11.2 0.0 1.7 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Peptidase_C12 PF01088.16 ETO31397.1 - 4.6e-57 192.6 0.0 7.5e-57 191.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 zf-U1 PF06220.7 ETO31399.1 - 0.031 13.8 0.6 0.086 12.4 0.2 1.9 2 0 0 2 2 2 0 U1 zinc finger Tubulin_C PF03953.12 ETO31400.1 - 4.2e-15 55.8 0.0 5.6e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 ETO31401.1 - 6.5e-71 238.5 0.0 8.5e-71 238.2 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.1 ETO31401.1 - 0.0016 17.9 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain zf-H2C2_2 PF13465.1 ETO31402.1 - 9.1e-10 38.3 24.9 1.2e-08 34.8 1.6 4.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 ETO31402.1 - 5e-08 32.8 14.1 0.074 13.4 0.9 5.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type PyrI_C PF02748.10 ETO31402.1 - 0.00071 18.9 6.9 0.22 11.0 0.2 3.3 2 1 0 2 2 2 2 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_6 PF13912.1 ETO31402.1 - 0.0036 17.1 14.5 0.22 11.4 0.1 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_4 PF13894.1 ETO31402.1 - 0.009 16.2 0.2 0.009 16.2 0.1 5.7 5 1 0 5 5 5 1 C2H2-type zinc finger zf-BED PF02892.10 ETO31402.1 - 0.014 15.1 2.2 0.014 15.1 1.5 5.3 3 1 1 4 4 4 0 BED zinc finger zf-CHCC PF10276.4 ETO31402.1 - 0.58 10.0 8.7 1.1 9.1 0.3 3.6 3 0 0 3 3 3 0 Zinc-finger domain CactinC_cactus PF09732.4 ETO31403.1 - 0.013 15.1 0.8 0.02 14.4 0.5 1.3 1 1 0 1 1 1 0 Cactus-binding C-terminus of cactin protein DUF2962 PF11176.3 ETO31403.1 - 0.046 13.2 0.0 0.08 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2962) DUF4562 PF15123.1 ETO31403.1 - 0.13 12.1 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4562) Neur_chan_memb PF02932.11 ETO31404.1 - 0.12 12.2 6.6 0.11 12.3 3.7 1.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region ALMT PF11744.3 ETO31404.1 - 0.77 8.3 3.9 0.26 9.8 0.1 1.8 1 1 1 2 2 2 0 Aluminium activated malate transporter Spt20 PF12090.3 ETO31404.1 - 1.7 7.9 9.7 0.21 10.9 2.4 2.0 2 0 0 2 2 2 0 Spt20 family BRF1 PF07741.8 ETO31404.1 - 2.1 8.6 13.5 3.5 7.9 7.9 2.1 2 0 0 2 2 2 0 Brf1-like TBP-binding domain BAF1_ABF1 PF04684.8 ETO31404.1 - 8.8 5.0 15.9 10 4.8 11.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Sigma_reg_C PF13791.1 ETO31404.1 - 9.6 6.2 10.4 11 6.0 4.2 2.1 2 0 0 2 2 2 0 Sigma factor regulator C-terminal DEAD PF00270.24 ETO31405.1 - 3.2e-17 62.5 0.0 2.9e-14 52.9 0.0 2.7 2 1 0 2 2 2 1 DEAD/DEAH box helicase RNase_E_G PF10150.4 ETO31405.1 - 0.11 11.7 1.5 0.19 10.9 1.0 1.4 1 0 0 1 1 1 0 Ribonuclease E/G family NOT2_3_5 PF04153.13 ETO31407.1 - 3e-19 69.2 6.8 3e-19 69.2 4.7 1.8 1 1 1 2 2 2 1 NOT2 / NOT3 / NOT5 family BLVR PF06375.6 ETO31407.1 - 3.3 7.5 12.3 0.16 11.7 1.7 2.4 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Pkinase PF00069.20 ETO31408.1 - 8.6e-22 77.5 0.0 8.6e-22 77.5 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO31408.1 - 2.4e-05 23.5 0.0 2.4e-05 23.5 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase dsDNA_bind PF01984.15 ETO31408.1 - 0.017 15.0 15.2 0.017 15.0 10.6 1.8 2 0 0 2 2 2 0 Double-stranded DNA-binding domain DUF2961 PF11175.3 ETO31408.1 - 0.093 12.0 5.7 0.047 13.0 2.6 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2961) Synapsin PF02078.11 ETO31408.1 - 0.094 12.8 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Synapsin, N-terminal domain Peptidase_S49_N PF08496.5 ETO31408.1 - 0.13 11.9 5.5 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Suf PF05843.9 ETO31408.1 - 0.5 10.0 14.1 0.8 9.3 9.8 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) BAF1_ABF1 PF04684.8 ETO31408.1 - 0.75 8.5 15.8 1.1 8.0 10.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor ABC2_membrane_3 PF12698.2 ETO31408.1 - 1.5 7.8 8.8 2.1 7.2 6.1 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Med3 PF11593.3 ETO31408.1 - 4.2 6.4 21.2 6 6.0 14.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal UPF0104 PF03706.8 ETO31409.1 - 2.9e-05 23.4 11.7 4.7e-05 22.8 8.1 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0104) DUF2207 PF09972.4 ETO31409.1 - 0.038 12.5 12.6 0.034 12.7 3.6 2.2 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) ABC2_membrane_2 PF12679.2 ETO31409.1 - 0.14 10.9 10.0 0.39 9.5 2.7 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF805 PF05656.9 ETO31409.1 - 0.2 11.4 12.2 0.14 11.9 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Cytochrom_B_N PF00033.14 ETO31409.1 - 0.78 9.0 10.7 1.9 7.7 7.4 1.9 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB MFS_1 PF07690.11 ETO31409.1 - 3.8 6.1 14.9 1.3e+02 1.0 10.4 2.2 1 1 0 1 1 1 0 Major Facilitator Superfamily DUF1049 PF06305.6 ETO31409.1 - 7.6 6.1 10.6 6.5 6.3 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) zf-DHHC PF01529.15 ETO31412.1 - 0.38 10.1 8.0 0.59 9.4 5.5 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase IBR PF01485.16 ETO31413.1 - 4.4e-10 39.2 6.6 4.4e-10 39.2 4.6 1.9 2 0 0 2 2 2 1 IBR domain Rad60-SLD PF11976.3 ETO31413.1 - 0.074 12.7 0.4 0.15 11.7 0.1 1.7 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like DUF4209 PF13910.1 ETO31413.1 - 0.084 12.9 0.2 0.24 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4209) FYVE_2 PF02318.11 ETO31413.1 - 0.2 11.5 7.7 0.14 12.0 4.2 1.6 1 1 0 1 1 1 0 FYVE-type zinc finger TEX19 PF15553.1 ETO31414.1 - 1.1 9.0 4.5 1.5 8.7 1.1 2.0 1 1 1 2 2 2 0 Testis-expressed protein 19 PLRV_ORF5 PF01690.12 ETO31414.1 - 5.1 6.1 12.8 5.9 5.9 8.9 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein tRNA-synt_2d PF01409.15 ETO31415.1 - 1.7e-88 296.0 0.0 1.9e-88 295.8 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 ETO31415.1 - 7.3e-08 31.5 0.2 0.00014 20.7 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 ETO31415.1 - 6.3e-07 29.1 0.1 1.2e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) TrmB PF01978.14 ETO31416.1 - 0.00043 19.9 0.0 0.00095 18.8 0.0 1.6 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB FeoC PF09012.5 ETO31416.1 - 0.00049 19.7 0.0 0.0011 18.5 0.0 1.7 1 0 0 1 1 1 1 FeoC like transcriptional regulator Fe_dep_repress PF01325.14 ETO31416.1 - 0.0047 16.8 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain PadR PF03551.9 ETO31416.1 - 0.019 14.7 0.0 0.047 13.4 0.0 1.8 1 1 0 1 1 1 0 Transcriptional regulator PadR-like family RPA_C PF08784.6 ETO31416.1 - 0.019 15.3 2.0 0.028 14.8 0.2 2.0 2 0 0 2 2 2 0 Replication protein A C terminal DDRGK PF09756.4 ETO31416.1 - 0.026 13.9 11.1 0.063 12.6 7.7 1.7 1 1 0 1 1 1 0 DDRGK domain B-block_TFIIIC PF04182.7 ETO31416.1 - 0.034 14.0 0.3 0.082 12.7 0.2 1.7 1 1 0 1 1 1 0 B-block binding subunit of TFIIIC HTH_24 PF13412.1 ETO31416.1 - 0.037 13.4 0.0 0.078 12.3 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding GntR PF00392.16 ETO31416.1 - 0.075 12.4 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family Pox_P21 PF05313.7 ETO31418.1 - 0.12 11.5 2.0 10 5.3 0.0 2.2 2 0 0 2 2 2 0 Poxvirus P21 membrane protein zf-RanBP PF00641.13 ETO31419.1 - 0.0079 15.2 5.4 0.0079 15.2 3.8 2.5 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others Sir1 PF11603.3 ETO31419.1 - 0.23 11.5 2.9 0.89 9.7 0.2 2.3 2 0 0 2 2 2 0 Regulatory protein Sir1 HSP70 PF00012.15 ETO31420.1 - 0.029 12.3 0.0 0.038 11.9 0.0 1.3 1 1 0 1 1 1 0 Hsp70 protein BcrAD_BadFG PF01869.15 ETO31420.1 - 0.083 12.1 0.0 0.23 10.7 0.0 1.8 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family Annexin PF00191.15 ETO31421.1 - 1.2e-24 85.9 13.9 2.6e-06 27.2 0.1 5.5 5 0 0 5 5 5 5 Annexin SBDS PF01172.13 ETO31421.1 - 0.029 14.1 1.5 0.22 11.3 0.1 2.8 3 0 0 3 3 3 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein COG6 PF06419.6 ETO31422.1 - 5.4e-29 100.8 0.0 4.4e-28 97.8 0.0 1.9 1 1 0 1 1 1 1 Conserved oligomeric complex COG6 RRN3 PF05327.6 ETO31422.1 - 0.01 13.9 1.2 0.014 13.5 0.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FKS1_dom1 PF14288.1 ETO31422.1 - 0.021 14.7 1.5 0.22 11.4 0.6 2.3 2 0 0 2 2 2 0 1,3-beta-glucan synthase subunit FKS1, domain-1 Lipl32 PF12103.3 ETO31422.1 - 0.11 12.0 0.6 0.17 11.2 0.4 1.4 1 0 0 1 1 1 0 Surface lipoprotein of Spirochaetales order Menin PF05053.8 ETO31422.1 - 0.11 10.6 0.3 0.13 10.3 0.2 1.1 1 0 0 1 1 1 0 Menin DUF912 PF06024.7 ETO31422.1 - 1 9.4 5.2 2.1 8.4 3.6 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Secretin_N_2 PF07655.8 ETO31422.1 - 3.3 8.1 14.2 2 8.8 8.5 1.6 2 0 0 2 2 2 0 Secretin N-terminal domain Armet PF10208.4 ETO31423.1 - 0.012 15.2 0.1 0.049 13.3 0.0 1.8 2 0 0 2 2 2 0 Degradation arginine-rich protein for mis-folding DUF3021 PF11457.3 ETO31423.1 - 5.9 6.7 7.1 6.4 6.6 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) Lectin_leg-like PF03388.8 ETO31424.1 - 0.0043 16.2 0.5 0.0043 16.2 0.3 1.8 2 0 0 2 2 2 1 Legume-like lectin family Corona_NS3b PF03053.9 ETO31424.1 - 0.054 13.0 0.1 0.083 12.4 0.1 1.3 1 0 0 1 1 1 0 ORF3b coronavirus protein Peptidase_M56 PF05569.6 ETO31424.1 - 0.25 10.2 1.7 0.29 10.0 0.4 1.6 1 1 0 1 1 1 0 BlaR1 peptidase M56 Rpr2 PF04032.11 ETO31425.1 - 0.00087 19.1 1.8 0.001 18.8 0.1 2.0 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain ArfGap PF01412.13 ETO31425.1 - 0.24 11.2 4.9 0.42 10.3 2.2 2.3 2 1 0 2 2 2 0 Putative GTPase activating protein for Arf zf-ribbon_3 PF13248.1 ETO31425.1 - 0.3 10.3 0.1 0.3 10.3 0.1 1.6 2 0 0 2 2 2 0 zinc-ribbon domain Copine PF07002.11 ETO31426.1 - 2.9e-37 127.6 0.1 4.7e-37 126.9 0.0 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.25 ETO31426.1 - 7.3e-28 96.2 1.2 6.8e-13 48.2 0.1 2.7 2 0 0 2 2 2 2 C2 domain DUF1945 PF09178.5 ETO31426.1 - 0.13 12.1 0.6 0.72 9.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1945) WW PF00397.21 ETO31427.1 - 3.1e-12 46.1 3.3 3.1e-12 46.1 2.3 2.7 3 0 0 3 3 3 1 WW domain Arabinose_Isome PF02610.10 ETO31428.1 - 0.04 12.8 0.1 0.057 12.3 0.1 1.2 1 0 0 1 1 1 0 L-arabinose isomerase Nop14 PF04147.7 ETO31429.1 - 0.00046 18.2 18.6 0.00052 18.1 12.9 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.7 ETO31429.1 - 0.0053 16.0 15.9 0.0059 15.9 11.0 1.1 1 0 0 1 1 1 1 SDA1 Menin PF05053.8 ETO31429.1 - 0.023 12.8 6.3 0.027 12.6 4.4 1.1 1 0 0 1 1 1 0 Menin eIF-3c_N PF05470.7 ETO31429.1 - 0.098 10.7 11.1 0.11 10.6 7.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Trypan_PARP PF05887.6 ETO31429.1 - 0.16 11.7 18.8 0.24 11.2 13.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NESP55 PF06390.7 ETO31429.1 - 0.19 11.0 10.1 0.27 10.5 7.0 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Daxx PF03344.10 ETO31429.1 - 0.2 10.1 24.3 0.25 9.8 16.8 1.1 1 0 0 1 1 1 0 Daxx Family RNA_polI_A34 PF08208.6 ETO31429.1 - 0.24 11.0 16.1 0.35 10.5 11.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 TRAP_alpha PF03896.11 ETO31429.1 - 0.26 10.2 12.6 0.39 9.6 8.7 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Mem_trans PF03547.13 ETO31429.1 - 0.4 8.9 2.9 0.43 8.8 2.0 1.1 1 0 0 1 1 1 0 Membrane transport protein RRN3 PF05327.6 ETO31429.1 - 0.53 8.3 7.7 0.55 8.2 5.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ycf1 PF05758.7 ETO31429.1 - 1.5 6.3 14.7 1.8 6.1 10.2 1.1 1 0 0 1 1 1 0 Ycf1 GAGA_bind PF06217.7 ETO31429.1 - 2.3 8.1 9.9 2.9 7.7 6.9 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family NARP1 PF12569.3 ETO31429.1 - 2.7 6.6 13.4 3.4 6.3 9.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF1510 PF07423.6 ETO31429.1 - 3.3 7.0 24.6 4.5 6.5 17.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RNase_H2-Ydr279 PF09468.5 ETO31429.1 - 3.6 6.7 12.5 4.9 6.2 8.7 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) HSP90 PF00183.13 ETO31429.1 - 8.4 4.6 22.3 11 4.2 15.5 1.2 1 0 0 1 1 1 0 Hsp90 protein N1221 PF07923.8 ETO31430.1 - 0.0061 15.4 0.0 0.0084 14.9 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein Ribosomal_L36e PF01158.13 ETO31431.1 - 4.7e-17 61.7 8.6 2.4e-13 49.8 1.3 2.4 1 1 1 2 2 2 2 Ribosomal protein L36e DUF4606 PF15379.1 ETO31431.1 - 0.2 11.7 5.1 0.35 10.9 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) PB1-F2 PF11986.3 ETO31431.1 - 0.71 9.9 4.2 0.33 11.0 1.5 1.5 2 0 0 2 2 2 0 Influenza A Proapoptotic protein AAA_23 PF13476.1 ETO31431.1 - 9.2 6.5 8.4 11 6.2 5.8 1.0 1 0 0 1 1 1 0 AAA domain DUF4187 PF13821.1 ETO31432.1 - 0.59 9.7 3.1 1.6 8.3 2.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4187) FAM70 PF14967.1 ETO31433.1 - 0.13 11.4 0.1 0.24 10.5 0.1 1.4 1 0 0 1 1 1 0 FAM70 protein Pkinase_Tyr PF07714.12 ETO31434.1 - 4.4e-50 170.1 0.0 6.5e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 ETO31434.1 - 1.3e-34 119.5 0.0 2.3e-34 118.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain DUF494 PF04361.8 ETO31434.1 - 0.17 11.5 0.1 20 4.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF494) WWE PF02825.15 ETO31435.1 - 0.0035 16.7 0.5 0.042 13.2 0.0 2.8 2 1 0 2 2 2 1 WWE domain DUF3333 PF11812.3 ETO31435.1 - 0.17 11.9 2.9 0.076 13.0 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3333) Ion_trans PF00520.26 ETO31435.1 - 0.19 10.9 8.5 0.018 14.2 2.9 1.7 2 1 0 2 2 2 0 Ion transport protein DUF912 PF06024.7 ETO31435.1 - 0.35 10.9 0.1 0.35 10.9 0.1 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ACR_tran PF00873.14 ETO31435.1 - 0.42 7.9 1.7 5.4 4.2 0.4 1.9 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family HA2 PF04408.18 ETO31437.1 - 3.8e-24 84.6 1.1 1.3e-23 82.9 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 ETO31437.1 - 9.6e-19 67.2 0.1 3.1e-18 65.6 0.1 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 ETO31437.1 - 1.6e-11 43.8 0.1 4.6e-10 39.2 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 ETO31437.1 - 3.3e-05 24.0 0.0 9.2e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 ETO31437.1 - 0.00021 20.3 0.0 0.00053 18.9 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein DEAD PF00270.24 ETO31437.1 - 0.00072 19.0 0.0 0.0018 17.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase S1 PF00575.18 ETO31437.1 - 0.0018 18.2 2.9 0.0082 16.2 2.0 2.1 1 1 0 1 1 1 1 S1 RNA binding domain AAA_19 PF13245.1 ETO31437.1 - 0.0058 16.3 0.1 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Arch_ATPase PF01637.13 ETO31437.1 - 0.028 14.1 0.0 0.067 12.8 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase PhoH PF02562.11 ETO31437.1 - 0.047 12.9 0.1 0.11 11.7 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein CDC45 PF02724.9 ETO31438.1 - 1.2 7.0 10.5 1.8 6.4 7.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.6 ETO31438.1 - 9.7 3.9 9.7 13 3.4 6.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Abhydrolase_6 PF12697.2 ETO31439.1 - 1e-16 61.5 0.0 5.9e-16 59.0 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETO31439.1 - 2.2e-06 27.4 0.2 2.2e-05 24.1 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETO31439.1 - 8.9e-05 22.2 0.0 0.00025 20.8 0.0 1.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETO31439.1 - 0.00018 21.3 0.0 0.00036 20.3 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Borrelia_lipo_2 PF06238.6 ETO31439.1 - 0.032 14.2 2.8 4.9 7.2 0.5 2.4 1 1 0 2 2 2 0 Borrelia burgdorferi BBR25 lipoprotein PH PF00169.24 ETO31440.1 - 4.5e-11 42.8 0.2 4.5e-11 42.8 0.1 3.5 3 2 0 3 3 3 1 PH domain Mcp5_PH PF12814.2 ETO31440.1 - 0.016 15.1 1.0 0.016 15.1 0.7 2.9 3 0 0 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology PH_11 PF15413.1 ETO31440.1 - 0.026 14.7 0.4 0.026 14.7 0.3 2.8 3 1 0 3 3 3 0 Pleckstrin homology domain PH_8 PF15409.1 ETO31440.1 - 0.53 10.3 5.1 0.25 11.4 0.2 3.0 2 1 0 2 2 2 0 Pleckstrin homology domain Cytochrom_c3_2 PF14537.1 ETO31441.1 - 0.05 13.9 0.1 0.05 13.9 0.1 1.8 2 0 0 2 2 2 0 Cytochrome c3 Cytochrom_B562 PF07361.6 ETO31441.1 - 0.054 13.9 0.5 0.13 12.6 0.4 1.7 1 0 0 1 1 1 0 Cytochrome b562 TruB_N PF01509.13 ETO31441.1 - 0.25 11.4 2.1 4.4 7.4 0.7 2.3 2 1 0 2 2 2 0 TruB family pseudouridylate synthase (N terminal domain) SapB_1 PF05184.10 ETO31441.1 - 1.4 8.8 5.3 2.4 8.1 0.3 2.8 3 0 0 3 3 3 0 Saposin-like type B, region 1 TMF_DNA_bd PF12329.3 ETO31442.1 - 0.0027 17.4 10.8 0.0027 17.4 7.5 3.7 1 1 3 4 4 4 2 TATA element modulatory factor 1 DNA binding Lebercilin PF15619.1 ETO31442.1 - 0.0027 17.1 12.2 0.0027 17.1 8.4 2.2 1 1 1 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease IncA PF04156.9 ETO31442.1 - 0.0057 16.2 11.5 0.0057 16.2 8.0 2.7 1 1 2 3 3 3 1 IncA protein Mod_r PF07200.8 ETO31442.1 - 0.02 14.8 23.3 0.075 12.9 8.9 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Myosin_tail_1 PF01576.14 ETO31442.1 - 0.045 11.4 34.6 0.35 8.5 23.7 1.8 1 1 0 1 1 1 0 Myosin tail CCDC155 PF14662.1 ETO31442.1 - 0.1 12.1 28.7 0.084 12.4 2.1 3.1 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 DUF2205 PF10224.4 ETO31442.1 - 0.78 9.3 18.8 1.9 8.1 1.9 4.0 1 1 4 5 5 4 0 Predicted coiled-coil protein (DUF2205) ATG16 PF08614.6 ETO31442.1 - 0.98 9.2 29.6 0.16 11.7 11.2 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 ETO31442.1 - 1.1 8.3 4.2 4.4 6.3 1.7 1.7 1 1 0 1 1 1 0 Reovirus sigma C capsid protein V_ATPase_I PF01496.14 ETO31442.1 - 1.2 6.9 12.2 1.4 6.6 8.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TPR_MLP1_2 PF07926.7 ETO31442.1 - 1.2 8.8 28.0 12 5.6 15.5 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF724 PF05266.9 ETO31442.1 - 1.3 8.6 23.5 1.5 8.4 4.6 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF724) KLRAQ PF10205.4 ETO31442.1 - 1.3 9.0 23.9 2.7 8.0 0.5 3.5 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein Ly49 PF08391.5 ETO31442.1 - 2 8.5 12.7 0.67 10.0 0.9 2.6 1 1 2 3 3 3 0 Ly49-like protein, N-terminal region ERM PF00769.14 ETO31442.1 - 2.6 7.4 29.3 0.018 14.5 7.7 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family HlyD PF00529.15 ETO31442.1 - 3.3 6.9 23.5 3.3e+02 0.3 16.3 2.2 1 1 0 1 1 1 0 HlyD family secretion protein DUF641 PF04859.7 ETO31442.1 - 4.2 7.1 20.7 0.2 11.4 2.6 3.6 1 1 3 4 4 4 0 Plant protein of unknown function (DUF641) Tropomyosin_1 PF12718.2 ETO31442.1 - 5.5 6.8 35.3 0.22 11.3 2.7 3.0 1 1 2 3 3 3 0 Tropomyosin like LRR_6 PF13516.1 ETO31443.1 - 6.9e-11 41.0 0.8 0.00048 19.9 0.1 4.3 4 0 0 4 4 4 2 Leucine Rich repeat LRR_7 PF13504.1 ETO31443.1 - 0.007 16.3 1.4 32 5.3 0.0 4.2 4 0 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.28 ETO31443.1 - 0.044 13.8 0.7 16 5.9 0.1 3.6 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.2 ETO31443.1 - 0.15 11.7 1.5 0.55 9.9 0.3 2.4 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO31443.1 - 0.32 10.7 1.8 1 9.1 0.7 2.3 2 1 0 2 2 2 0 Leucine rich repeat Kelch_6 PF13964.1 ETO31446.1 - 0.01 15.9 0.3 0.59 10.4 0.1 2.7 2 0 0 2 2 2 0 Kelch motif Kelch_5 PF13854.1 ETO31446.1 - 0.014 15.2 0.1 0.12 12.3 0.0 2.6 2 0 0 2 2 2 0 Kelch motif FerI PF08151.7 ETO31446.1 - 0.063 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 FerI (NUC094) domain Kelch_1 PF01344.20 ETO31447.1 - 1.5e-09 37.2 1.1 9.8e-08 31.4 0.6 2.3 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETO31447.1 - 3.7e-08 33.2 0.9 1.2e-05 25.2 0.1 2.2 1 1 1 2 2 2 2 Kelch motif Kelch_4 PF13418.1 ETO31447.1 - 1.6e-07 30.9 0.3 0.00038 20.1 0.0 2.2 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO31447.1 - 5.1e-05 23.1 2.4 0.00017 21.4 0.8 2.0 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO31447.1 - 0.00011 22.1 0.0 0.00028 20.9 0.0 1.6 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO31447.1 - 0.00044 19.9 0.5 0.068 12.9 0.3 2.3 2 0 0 2 2 2 1 Kelch motif DUF3866 PF12982.2 ETO31447.1 - 0.098 11.6 0.4 0.12 11.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3866) Phage_Gp23 PF10669.4 ETO31447.1 - 0.7 10.0 7.2 1.2 9.2 5.0 1.4 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Shisa PF13908.1 ETO31448.1 - 0.0026 17.9 0.5 0.003 17.7 0.3 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator PT PF04886.7 ETO31448.1 - 0.74 9.1 7.2 0.24 10.7 2.3 2.0 2 0 0 2 2 2 0 PT repeat Pinin_SDK_memA PF04696.8 ETO31449.1 - 0.0026 17.3 4.2 0.0044 16.6 2.9 1.4 1 0 0 1 1 1 1 pinin/SDK/memA/ protein conserved region LETM1 PF07766.8 ETO31450.1 - 0.089 11.8 0.1 0.15 11.0 0.0 1.5 2 0 0 2 2 2 0 LETM1-like protein 60KD_IMP PF02096.15 ETO31452.1 - 0.026 14.2 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 60Kd inner membrane protein Ivy PF08816.6 ETO31452.1 - 0.053 13.5 0.8 0.11 12.4 0.5 1.6 1 1 0 1 1 1 0 Inhibitor of vertebrate lysozyme (Ivy) NFRKB_winged PF14465.1 ETO31452.1 - 0.075 12.8 0.2 0.16 11.7 0.1 1.6 1 1 1 2 2 2 0 NFRKB Winged Helix-like Ras PF00071.17 ETO31454.1 - 2.1e-24 85.7 0.7 2.9e-24 85.2 0.5 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO31454.1 - 2.1e-05 24.9 2.6 2.1e-05 24.9 0.5 2.0 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO31454.1 - 0.00058 19.1 0.1 0.00087 18.5 0.1 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO31454.1 - 0.0012 18.3 0.1 0.0018 17.7 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1_C PF08438.5 ETO31454.1 - 0.11 12.7 0.3 0.3 11.3 0.1 1.8 2 0 0 2 2 2 0 GTPase of unknown function C-terminal DUF4312 PF14189.1 ETO31455.1 - 0.0049 16.6 5.0 0.13 12.0 0.2 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4312) Muted PF14942.1 ETO31456.1 - 0.0007 19.4 5.8 0.0007 19.4 4.0 3.5 1 1 2 3 3 3 1 Organelle biogenesis, Muted-like protein ETRAMP PF09716.5 ETO31456.1 - 3.6 7.6 0.0 3.6 7.6 0.0 4.9 2 2 1 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) DUF948 PF06103.6 ETO31456.1 - 8.7 6.2 10.8 2.7 7.8 2.5 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TPT PF03151.11 ETO31457.1 - 7.6e-10 38.6 11.0 8.6e-10 38.4 5.2 2.2 3 0 0 3 3 3 1 Triose-phosphate Transporter family EmrE PF13536.1 ETO31457.1 - 0.0071 16.5 6.5 0.025 14.7 2.4 2.4 2 0 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 ETO31457.1 - 0.018 15.0 6.5 0.018 15.0 4.5 2.0 2 0 0 2 2 2 0 EamA-like transporter family UAA PF08449.6 ETO31457.1 - 0.03 13.2 0.7 0.03 13.2 0.5 1.6 2 0 0 2 2 2 0 UAA transporter family COX14 PF14880.1 ETO31457.1 - 0.049 13.2 0.2 0.18 11.4 0.0 2.1 3 0 0 3 3 3 0 Cytochrome oxidase c assembly DUF4131 PF13567.1 ETO31457.1 - 4.6 6.6 5.6 29 3.9 2.9 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) UCH PF00443.24 ETO31458.1 - 3e-15 56.0 0.1 3e-15 56.0 0.1 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO31458.1 - 2.2e-07 30.6 0.6 3.8e-07 29.8 0.1 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Ipi1_N PF12333.3 ETO31458.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation UCH PF00443.24 ETO31459.1 - 4.3e-25 88.3 0.9 4.3e-25 88.3 0.6 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO31459.1 - 1.7e-17 63.7 1.9 1.7e-17 63.7 1.3 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Kinesin PF00225.18 ETO31462.1 - 1.3e-09 37.2 0.4 1.3e-09 37.2 0.3 2.3 2 1 1 3 3 3 1 Kinesin motor domain Nucleotid_trans PF03407.11 ETO31463.1 - 2.8e-12 46.8 0.1 4e-12 46.3 0.1 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase FNIP PF05725.7 ETO31464.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.7 1 1 0 1 1 1 0 FNIP Repeat ENTH PF01417.15 ETO31466.1 - 2.7e-06 27.2 0.0 4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 ENTH domain Peptidase_C65 PF10275.4 ETO31466.1 - 0.043 13.1 0.2 0.062 12.6 0.1 1.2 1 0 0 1 1 1 0 Peptidase C65 Otubain LNS2 PF08235.8 ETO31467.1 - 0.081 12.4 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) DUF2341 PF10102.4 ETO31467.1 - 3.4 7.8 7.1 6.3 7.0 1.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2341) Rieske PF00355.21 ETO31468.1 - 1.2e-14 53.6 0.5 2e-14 52.9 0.4 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.9 ETO31468.1 - 7.1e-05 22.9 0.1 0.00038 20.6 0.0 2.1 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region DUF563 PF04577.9 ETO31469.1 - 2.3e-23 83.1 0.3 6e-23 81.8 0.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF563) Innate_immun PF12782.2 ETO31470.1 - 0.68 9.1 7.5 1.2 8.2 5.2 1.4 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family AAA PF00004.24 ETO31471.1 - 0.021 15.0 0.2 0.065 13.4 0.0 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETO31471.1 - 0.023 14.3 0.1 0.087 12.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) SCHIP-1 PF10148.4 ETO31471.1 - 0.03 13.7 1.5 0.17 11.2 0.3 2.2 2 0 0 2 2 2 0 Schwannomin-interacting protein 1 AAA_22 PF13401.1 ETO31471.1 - 0.038 14.1 0.0 0.55 10.3 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 ETO31471.1 - 0.12 12.3 0.2 1.3 8.9 0.2 2.6 1 1 1 2 2 2 0 AAA ATPase domain ClpB_D2-small PF10431.4 ETO31471.1 - 3.6 7.5 6.8 6.4 6.7 0.0 3.4 4 0 0 4 4 4 0 C-terminal, D2-small domain, of ClpB protein DUF3435 PF11917.3 ETO31472.1 - 0.077 11.7 3.6 0.084 11.5 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Voldacs PF03517.8 ETO31472.1 - 1.1 9.0 6.1 1.7 8.4 4.0 1.4 1 1 0 1 1 1 0 Regulator of volume decrease after cellular swelling Exonuc_VII_L PF02601.10 ETO31472.1 - 2.1 7.4 6.5 0.3 10.2 1.3 1.6 1 1 1 2 2 2 0 Exonuclease VII, large subunit IncA PF04156.9 ETO31473.1 - 0.0049 16.5 8.6 0.0049 16.5 6.0 1.1 1 0 0 1 1 1 1 IncA protein CENP-Q PF13094.1 ETO31473.1 - 0.03 14.3 7.7 0.032 14.2 5.4 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Atg14 PF10186.4 ETO31473.1 - 0.034 13.0 7.4 0.041 12.8 5.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Rootletin PF15035.1 ETO31473.1 - 0.14 12.1 7.5 0.17 11.8 5.2 1.3 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion HAUS-augmin3 PF14932.1 ETO31473.1 - 0.17 11.0 7.1 0.18 10.9 4.9 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Erp_C PF06780.6 ETO31473.1 - 0.27 11.0 7.6 0.36 10.6 5.3 1.2 1 0 0 1 1 1 0 Erp protein C-terminus DivIVA PF05103.8 ETO31473.1 - 0.33 11.0 8.3 0.43 10.6 5.7 1.2 1 0 0 1 1 1 0 DivIVA protein Vfa1 PF08432.5 ETO31473.1 - 0.44 10.5 7.5 0.52 10.3 5.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 KIAA1430 PF13879.1 ETO31473.1 - 0.47 10.9 7.4 0.58 10.6 5.1 1.1 1 0 0 1 1 1 0 KIAA1430 homologue Spc24 PF08286.6 ETO31473.1 - 1 9.0 6.8 1.4 8.6 4.7 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF972 PF06156.8 ETO31473.1 - 1.8 8.9 7.7 2.5 8.4 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF2205 PF10224.4 ETO31473.1 - 2.2 7.9 9.3 0.55 9.8 4.0 1.8 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) ADIP PF11559.3 ETO31473.1 - 4.5 7.1 12.2 17 5.3 8.5 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Mto2_bdg PF12808.2 ETO31473.1 - 9.6 6.4 12.3 1.9 8.6 5.0 2.3 2 1 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region FrhB_FdhB_C PF04432.8 ETO31475.1 - 0.25 10.7 1.5 2 7.8 0.2 2.1 1 1 1 2 2 2 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus WD40 PF00400.27 ETO31476.1 - 5.6e-78 254.2 24.4 4.3e-15 54.9 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO31476.1 - 3.1e-07 28.9 8.5 0.18 9.8 0.1 5.2 1 1 2 4 4 4 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO31476.1 - 0.00021 20.8 0.1 0.00075 19.0 0.0 2.2 2 1 0 2 2 2 1 PQQ-like domain Resistin PF06954.6 ETO31476.1 - 0.0033 17.6 1.3 26 5.1 0.0 4.3 2 2 2 4 4 4 0 Resistin DUF2415 PF10313.4 ETO31476.1 - 0.082 12.5 0.0 7.1 6.3 0.0 2.9 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) PD40 PF07676.7 ETO31476.1 - 0.088 12.4 6.8 0.62 9.7 0.1 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat SPRY PF00622.23 ETO31477.1 - 8.8e-05 22.5 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 SPRY domain Guanylate_cyc PF00211.15 ETO31477.1 - 0.18 11.1 0.3 3.8 6.8 0.0 2.1 1 1 1 2 2 2 0 Adenylate and Guanylate cyclase catalytic domain DnaJ PF00226.26 ETO31478.1 - 3.9e-13 48.9 1.6 9e-13 47.7 1.1 1.6 1 0 0 1 1 1 1 DnaJ domain CorA PF01544.13 ETO31478.1 - 0.43 9.5 6.4 1.8 7.5 0.7 2.3 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF3439 PF11921.3 ETO31478.1 - 2.1 8.1 7.2 0.63 9.7 3.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF4023 PF13215.1 ETO31478.1 - 2.2 8.1 6.4 0.43 10.3 1.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4023) P22_AR_C PF10548.4 ETO31480.1 - 0.062 13.1 0.1 0.22 11.4 0.1 1.8 1 0 0 1 1 1 0 P22AR C-terminal domain SelR PF01641.13 ETO31481.1 - 1.4e-31 108.7 0.3 1.8e-31 108.4 0.2 1.2 1 0 0 1 1 1 1 SelR domain FA_hydroxylase PF04116.8 ETO31482.1 - 1.2e-08 35.3 18.6 2.3e-08 34.4 12.9 1.5 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Thioredoxin PF00085.15 ETO31483.1 - 1.3e-07 31.2 0.0 2.9e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 ETO31483.1 - 0.0029 17.7 0.1 0.0045 17.1 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain DUF912 PF06024.7 ETO31485.1 - 0.71 9.9 5.9 1.3 9.0 4.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) 2-Hacid_dh PF00389.25 ETO31486.1 - 0.00082 18.8 0.0 0.0023 17.4 0.0 1.7 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DUF912 PF06024.7 ETO31486.1 - 0.015 15.3 0.9 4.9 7.2 0.4 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PDEase_I PF00233.14 ETO31489.1 - 2.4e-09 37.3 0.0 2.4e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase TraV PF09676.5 ETO31490.1 - 0.021 15.4 0.2 0.021 15.4 0.1 2.4 2 1 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) Sporozoite_P67 PF05642.6 ETO31490.1 - 0.027 12.3 4.2 0.053 11.3 2.9 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM176 PF14851.1 ETO31490.1 - 0.039 13.6 0.7 0.039 13.6 0.5 3.0 1 1 2 3 3 3 0 FAM176 family TRAP_alpha PF03896.11 ETO31490.1 - 0.48 9.3 9.7 0.3 10.0 1.8 2.2 1 1 1 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Vfa1 PF08432.5 ETO31490.1 - 1.4 8.9 19.6 2 8.4 5.1 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Peptidase_S49_N PF08496.5 ETO31490.1 - 1.6 8.5 8.6 2.2 8.0 1.2 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Zip PF02535.17 ETO31490.1 - 1.7 7.6 3.4 0.9 8.4 0.4 1.8 1 1 1 2 2 2 0 ZIP Zinc transporter Nucleoplasmin PF03066.10 ETO31490.1 - 1.7 8.1 10.6 0.29 10.6 3.0 2.2 2 0 0 2 2 2 0 Nucleoplasmin CDC45 PF02724.9 ETO31490.1 - 9 4.1 15.2 0.054 11.5 3.0 2.0 2 0 0 2 2 2 0 CDC45-like protein Wzy_C PF04932.10 ETO31491.1 - 0.49 10.1 13.8 0.56 9.9 9.6 1.3 1 0 0 1 1 1 0 O-Antigen ligase AA_permease_2 PF13520.1 ETO31491.1 - 0.56 8.6 18.0 0.53 8.7 12.5 1.1 1 0 0 1 1 1 0 Amino acid permease CbiQ PF02361.11 ETO31491.1 - 2.9 7.4 15.5 3.1 7.3 10.8 1.1 1 0 0 1 1 1 0 Cobalt transport protein Pex24p PF06398.6 ETO31491.1 - 3.1 6.4 7.2 3.1 6.5 5.0 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin O-antigen_lig PF13425.1 ETO31491.1 - 8.2 6.4 16.0 12 5.9 11.1 1.4 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF3458 PF11940.3 ETO31492.1 - 3.9e-86 289.1 0.0 9.8e-53 179.2 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3458) Peptidase_M1 PF01433.15 ETO31492.1 - 1.6e-47 162.4 0.1 1.6e-33 116.3 0.1 2.4 2 0 0 2 2 2 2 Peptidase family M1 Peptidase_MA_2 PF13485.1 ETO31492.1 - 4.2e-11 42.9 0.0 1.8e-09 37.7 0.0 2.4 2 0 0 2 2 2 1 Peptidase MA superfamily zf-CCCH PF00642.19 ETO31493.1 - 1.3e-05 24.7 5.5 1.9e-05 24.1 3.8 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Osmo_CC PF08946.5 ETO31493.1 - 0.038 14.0 4.5 0.039 13.9 1.8 1.9 2 0 0 2 2 2 0 Osmosensory transporter coiled coil WD40 PF00400.27 ETO31494.1 - 2e-25 87.6 19.0 1e-09 37.8 0.0 7.6 8 1 0 8 8 8 3 WD domain, G-beta repeat PD40 PF07676.7 ETO31494.1 - 0.0086 15.7 0.0 7.6 6.3 0.0 4.3 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO31494.1 - 0.016 13.3 0.8 4.5 5.2 0.0 3.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Nbas_N PF15492.1 ETO31494.1 - 0.049 12.7 0.9 13 4.7 0.0 3.2 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Utp12 PF04003.7 ETO31495.1 - 7e-15 54.8 0.2 9.4e-15 54.4 0.1 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family Hydrolase_like PF13242.1 ETO31497.1 - 0.00081 19.0 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Peptidase_C14 PF00656.17 ETO31498.1 - 3.1e-09 36.9 6.9 5.5e-09 36.0 0.3 3.2 2 2 0 2 2 2 1 Caspase domain zf-TRAF PF02176.13 ETO31498.1 - 0.00079 19.7 4.1 0.00079 19.7 2.8 2.9 2 0 0 2 2 2 1 TRAF-type zinc finger HSP70 PF00012.15 ETO31499.1 - 2.6e-27 95.0 0.0 3.4e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein CAP_GLY PF01302.20 ETO31501.1 - 3.5e-60 199.6 14.3 1.4e-15 56.6 0.1 4.3 4 0 0 4 4 4 4 CAP-Gly domain V_ATPase_I PF01496.14 ETO31501.1 - 0.44 8.3 2.5 0.59 7.9 1.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family WD40 PF00400.27 ETO31502.1 - 3.6e-80 261.2 18.3 6.7e-13 47.9 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO31502.1 - 3.2e-08 32.1 13.0 0.015 13.4 0.0 5.4 1 1 5 6 6 6 3 Nucleoporin Nup120/160 Resistin PF06954.6 ETO31502.1 - 0.00033 20.8 1.8 27 5.1 0.0 5.1 2 2 3 5 5 5 0 Resistin Asp_decarbox PF02261.11 ETO31502.1 - 0.0047 16.5 0.1 1.6 8.3 0.0 3.1 3 1 0 3 3 3 1 Aspartate decarboxylase PQQ_2 PF13360.1 ETO31502.1 - 0.0054 16.2 0.2 0.022 14.2 0.1 2.0 1 1 0 1 1 1 1 PQQ-like domain DUF1258 PF06869.7 ETO31502.1 - 0.0065 15.5 3.2 0.71 8.9 0.1 3.3 2 1 0 3 3 3 2 Protein of unknown function (DUF1258) PD40 PF07676.7 ETO31502.1 - 0.037 13.7 2.3 2.8 7.7 0.0 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF1727 PF08353.5 ETO31502.1 - 0.091 12.3 0.9 1.1 8.8 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1727) Complex1_LYR PF05347.10 ETO31503.1 - 0.00029 20.5 1.1 0.00049 19.8 0.2 1.8 2 1 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 ETO31503.1 - 0.00036 20.6 0.2 0.00036 20.6 0.2 2.0 2 1 0 2 2 2 1 Complex1_LYR-like Clathrin_H_link PF13838.1 ETO31503.1 - 0.064 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Clathrin-H-link UPF0203 PF05254.7 ETO31503.1 - 1.2 9.0 6.3 1.8 8.4 0.9 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) Kelch_4 PF13418.1 ETO31504.1 - 8.3e-05 22.2 2.2 0.012 15.4 0.1 3.3 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO31504.1 - 0.00083 19.0 7.7 0.29 10.9 0.5 4.2 3 1 1 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO31504.1 - 0.00098 19.2 9.8 0.43 10.8 0.0 5.1 4 2 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 ETO31504.1 - 0.0089 15.5 6.1 0.68 9.5 0.7 4.3 4 0 0 4 4 4 1 Kelch motif TPR_12 PF13424.1 ETO31506.1 - 1.4e-96 316.5 16.9 2.6e-21 75.3 0.1 6.6 4 1 1 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETO31506.1 - 1.9e-62 204.4 54.5 6.7e-09 34.9 0.4 10.7 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 ETO31506.1 - 1.3e-59 197.7 34.3 2.8e-13 49.2 0.1 7.1 5 2 2 7 7 6 6 TPR repeat TPR_7 PF13176.1 ETO31506.1 - 3e-58 189.0 13.0 6.1e-07 28.7 0.0 10.8 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_10 PF13374.1 ETO31506.1 - 9.4e-49 162.0 0.0 4.5e-06 26.4 0.0 10.3 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_8 PF13181.1 ETO31506.1 - 2.8e-48 158.0 56.2 2.1e-07 30.2 1.2 11.3 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.12 ETO31506.1 - 3.6e-48 157.6 39.1 1.2e-06 27.9 0.0 10.7 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_17 PF13431.1 ETO31506.1 - 2.6e-22 77.1 15.4 0.048 13.8 0.0 11.5 10 2 0 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO31506.1 - 1.3e-15 57.5 0.0 0.0001 22.8 0.0 6.8 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO31506.1 - 1.7e-15 56.0 0.0 3.3 8.6 0.0 9.5 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO31506.1 - 4.5e-14 51.8 15.8 1 9.9 0.0 9.7 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_3 PF07720.7 ETO31506.1 - 2.5e-12 46.3 26.7 0.0057 16.4 0.5 7.3 8 0 0 8 8 7 5 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO31506.1 - 8e-12 44.2 1.3 0.16 11.2 0.0 7.1 8 0 0 8 8 8 3 SHNi-TPR Apc3 PF12895.2 ETO31506.1 - 4.3e-10 39.5 24.6 0.00014 21.9 3.6 5.2 3 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 DUF2225 PF09986.4 ETO31506.1 - 7e-10 38.7 20.5 0.0048 16.3 0.4 5.9 1 1 5 6 6 6 4 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.13 ETO31506.1 - 2.5e-08 33.6 25.5 1.1 9.1 0.2 8.5 8 0 0 8 8 8 4 MIT (microtubule interacting and transport) domain TPR_19 PF14559.1 ETO31506.1 - 8.1e-07 29.2 4.2 0.08 13.2 0.0 5.8 4 1 3 7 7 7 3 Tetratricopeptide repeat PPR PF01535.15 ETO31506.1 - 0.037 14.0 23.0 2.6 8.2 0.3 8.4 10 0 0 10 10 8 0 PPR repeat BCAS2 PF05700.6 ETO31506.1 - 0.05 13.0 8.7 0.11 11.9 2.8 2.7 2 0 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) DUF627 PF04781.7 ETO31506.1 - 0.067 12.8 17.8 9.6 5.8 0.1 6.9 5 2 2 7 7 7 0 Protein of unknown function (DUF627) Sel1 PF08238.7 ETO31506.1 - 0.79 10.4 22.2 38 5.1 0.1 8.1 9 0 0 9 9 9 0 Sel1 repeat FliD_N PF02465.13 ETO31506.1 - 2.7 8.4 5.2 12 6.3 0.6 2.8 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus TPR_12 PF13424.1 ETO31507.1 - 4.7e-69 228.3 17.0 4.7e-22 77.7 0.2 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO31507.1 - 1.7e-41 139.7 38.8 1.6e-12 46.9 2.6 4.8 2 1 2 5 5 5 5 TPR repeat TPR_7 PF13176.1 ETO31507.1 - 2e-37 124.0 10.8 1.9e-06 27.2 0.0 7.3 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_10 PF13374.1 ETO31507.1 - 1.9e-35 119.7 0.0 7.8e-06 25.6 0.0 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETO31507.1 - 6.7e-32 107.7 52.3 3.8e-08 32.6 0.7 8.2 8 1 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.12 ETO31507.1 - 4.6e-28 94.8 36.7 1.4e-05 24.6 0.2 8.4 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.1 ETO31507.1 - 2.7e-25 86.1 49.6 2.5e-05 23.7 0.6 8.4 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 ETO31507.1 - 7.4e-12 45.6 0.0 0.71 10.6 0.0 5.2 3 2 1 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO31507.1 - 2.1e-09 37.1 0.2 6.5 7.6 0.0 6.6 7 0 0 7 7 6 1 Tetratricopeptide repeat MIT PF04212.13 ETO31507.1 - 4.8e-09 35.9 21.1 0.079 12.8 0.3 6.4 5 1 1 6 6 6 4 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 ETO31507.1 - 2.1e-08 34.0 15.1 4.7 7.8 0.0 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO31507.1 - 1.1e-06 28.3 23.9 0.03 14.5 0.0 8.7 5 3 2 7 7 7 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO31507.1 - 6.3e-06 25.3 0.2 3.9 6.8 0.0 4.8 4 0 0 4 4 4 2 SHNi-TPR TPR_19 PF14559.1 ETO31507.1 - 3.9e-05 23.9 5.1 0.054 13.8 0.0 5.4 4 2 2 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO31507.1 - 0.0001 22.3 17.2 0.0017 18.4 3.5 4.0 1 1 3 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 DUF2225 PF09986.4 ETO31507.1 - 0.00029 20.3 21.5 0.4 10.1 0.9 5.3 1 1 3 4 4 4 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_9 PF13371.1 ETO31507.1 - 0.011 15.5 0.3 8.2 6.3 0.0 3.4 5 0 0 5 5 4 0 Tetratricopeptide repeat Rab3-GTPase_cat PF13890.1 ETO31507.1 - 0.014 14.7 1.0 0.025 13.9 0.7 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit TPR_3 PF07720.7 ETO31507.1 - 0.085 12.6 22.3 3.1 7.7 0.2 6.5 6 1 0 6 6 6 0 Tetratricopeptide repeat ERG4_ERG24 PF01222.12 ETO31508.1 - 1.8e-87 293.6 19.8 2.2e-87 293.4 13.7 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 ETO31508.1 - 3.5 6.8 15.3 19 4.4 10.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) LRR_4 PF12799.2 ETO31509.1 - 2.4e-10 39.7 17.9 7.8e-05 22.2 0.3 4.0 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETO31509.1 - 6.6e-07 28.5 12.9 1.5 9.1 0.3 6.6 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_8 PF13855.1 ETO31509.1 - 3.4e-06 26.7 9.4 5.2e-05 22.9 1.7 3.2 2 1 1 3 3 3 3 Leucine rich repeat Herpes_glycop PF01528.11 ETO31509.1 - 0.00052 18.8 0.4 0.00071 18.3 0.3 1.1 1 0 0 1 1 1 1 Herpesvirus glycoprotein M LRR_6 PF13516.1 ETO31509.1 - 0.54 10.4 9.0 5.2 7.4 0.0 4.7 5 0 0 5 5 5 0 Leucine Rich repeat LRR_7 PF13504.1 ETO31509.1 - 0.7 10.3 11.0 45 4.9 0.1 5.3 5 0 0 5 5 5 0 Leucine rich repeat DUF3487 PF11990.3 ETO31511.1 - 0.12 11.8 0.3 1.3 8.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) DUF3377 PF11857.3 ETO31511.1 - 4.8 6.8 5.5 2.7 7.6 0.6 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3377) Topoisom_bac PF01131.15 ETO31512.1 - 4.5e-88 295.8 0.0 5.1e-88 295.6 0.0 1.0 1 0 0 1 1 1 1 DNA topoisomerase WD40 PF00400.27 ETO31513.1 - 1.4e-69 227.6 19.0 3.9e-12 45.5 0.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO31513.1 - 6.4e-09 35.8 0.4 0.039 13.6 0.0 3.5 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO31513.1 - 4.3e-08 31.7 5.5 0.062 11.4 0.0 4.6 1 1 4 5 5 5 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO31513.1 - 0.00049 18.5 0.1 0.96 7.6 0.0 3.3 1 1 4 5 5 5 3 Cytochrome D1 heme domain HARP PF07443.8 ETO31513.1 - 0.012 14.9 0.3 14 5.1 0.0 4.1 4 0 0 4 4 4 0 HepA-related protein (HARP) Str_synth PF03088.11 ETO31513.1 - 0.069 13.1 0.2 5.4 7.1 0.0 3.5 1 1 2 3 3 3 0 Strictosidine synthase Proteasome_A_N PF10584.4 ETO31513.1 - 1.5 8.2 3.6 51 3.3 0.0 3.7 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature zf-TRAF PF02176.13 ETO31514.1 - 0.0011 19.3 1.5 0.0034 17.7 0.4 2.4 1 1 0 1 1 1 1 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 ETO31514.1 - 0.15 12.0 5.2 0.18 11.8 0.1 3.7 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Lyase_8_N PF08124.6 ETO31516.1 - 0.0071 15.2 7.2 0.0096 14.8 5.0 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain BLOC1_2 PF10046.4 ETO31516.1 - 0.029 14.4 6.4 0.025 14.6 3.3 1.8 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Herpes_UL17 PF04559.7 ETO31516.1 - 0.047 12.2 0.0 0.087 11.3 0.0 1.5 1 1 0 1 1 1 0 Herpesvirus UL17 protein HsdM_N PF12161.3 ETO31516.1 - 0.077 13.4 8.1 0.54 10.6 5.6 2.0 1 1 0 1 1 1 0 HsdM N-terminal domain RBFA PF02033.13 ETO31516.1 - 0.089 12.8 3.2 0.24 11.4 2.2 1.8 1 1 0 1 1 1 0 Ribosome-binding factor A Orbi_VP5 PF00901.12 ETO31516.1 - 0.11 10.6 5.4 0.04 12.1 1.5 1.6 1 1 1 2 2 2 0 Orbivirus outer capsid protein VP5 Ferritin-like PF12902.2 ETO31516.1 - 0.77 9.3 5.1 1.6 8.2 0.9 2.0 1 1 1 2 2 2 0 Ferritin-like PPR_3 PF13812.1 ETO31517.1 - 1.6e-05 24.7 1.8 24 5.5 0.0 5.7 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 ETO31517.1 - 0.00022 21.1 0.2 0.015 15.2 0.1 4.9 5 1 1 6 6 6 2 PPR repeat family PPR PF01535.15 ETO31517.1 - 0.013 15.4 5.6 32 4.7 0.0 5.2 5 0 0 5 5 5 0 PPR repeat Mito_carr PF00153.22 ETO31518.1 - 1.1e-51 172.4 1.4 5.6e-17 61.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3770 PF12603.3 ETO31518.1 - 0.00057 19.0 0.1 0.00084 18.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3770) zf-RVT PF13966.1 ETO31519.1 - 0.0052 17.0 0.9 0.056 13.7 0.7 2.4 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase DUF977 PF06163.6 ETO31519.1 - 0.11 12.1 0.0 7.2 6.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF977) Mer2 PF09074.5 ETO31520.1 - 0.026 14.4 12.8 0.048 13.5 8.9 1.4 1 1 0 1 1 1 0 Mer2 Ste5_C PF12194.3 ETO31520.1 - 0.043 13.4 5.1 0.1 12.2 2.6 2.0 2 0 0 2 2 2 0 Protein kinase Fus3-binding APG6 PF04111.7 ETO31520.1 - 0.065 12.2 12.1 0.098 11.6 8.4 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Glyco_transf_41 PF13844.1 ETO31520.1 - 0.1 10.5 2.4 0.13 10.1 1.6 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 41 Mitofilin PF09731.4 ETO31520.1 - 0.41 9.2 18.4 0.66 8.5 12.8 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF3186 PF11382.3 ETO31520.1 - 0.43 9.6 3.2 0.58 9.2 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) WXG100 PF06013.7 ETO31520.1 - 0.55 10.2 5.5 14 5.7 1.9 2.4 1 1 1 2 2 2 0 Proteins of 100 residues with WXG IncA PF04156.9 ETO31520.1 - 0.66 9.5 17.0 1.4 8.4 11.7 1.6 1 1 0 1 1 1 0 IncA protein Fib_alpha PF08702.5 ETO31520.1 - 0.69 10.0 17.2 1.4 8.9 11.9 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family COG5 PF10392.4 ETO31520.1 - 4.1 7.3 10.9 0.3 11.0 2.0 2.7 2 1 1 3 3 3 0 Golgi transport complex subunit 5 PEP-utilisers_N PF05524.8 ETO31520.1 - 4.3 7.1 6.3 6.2 6.6 3.3 1.9 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal PRP38_assoc PF12871.2 ETO31521.1 - 9.6e-05 22.8 17.7 9.6e-05 22.8 12.2 7.4 5 3 1 6 6 6 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term WD40 PF00400.27 ETO31522.1 - 1.3e-61 202.4 12.3 1.5e-10 40.5 0.4 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO31522.1 - 5.1e-10 39.3 1.4 3.8e-07 30.0 0.2 3.4 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO31522.1 - 6.4e-08 31.1 1.4 0.0095 14.1 0.2 4.7 1 1 3 4 4 4 3 Nucleoporin Nup120/160 PD40 PF07676.7 ETO31522.1 - 3.1e-07 29.9 7.7 0.0037 16.8 0.0 5.6 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO31522.1 - 2.2e-05 24.0 0.0 0.0014 18.1 0.0 2.7 1 1 1 2 2 2 2 PQQ-like domain Cytochrom_D1 PF02239.11 ETO31522.1 - 4.1e-05 22.0 0.3 0.031 12.5 0.0 2.6 1 1 2 3 3 3 3 Cytochrome D1 heme domain DPPIV_N PF00930.16 ETO31522.1 - 0.0001 21.0 0.1 0.026 13.1 0.0 3.0 1 1 2 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Coatomer_WDAD PF04053.9 ETO31522.1 - 0.00046 19.0 1.8 0.029 13.1 0.2 2.2 1 1 1 2 2 2 2 Coatomer WD associated region Ricin_B_lectin PF00652.17 ETO31522.1 - 0.00048 20.1 6.0 0.39 10.7 0.1 3.4 1 1 2 3 3 3 2 Ricin-type beta-trefoil lectin domain Nucleoporin_N PF08801.6 ETO31522.1 - 0.0017 17.1 9.2 1.5 7.4 0.0 4.0 1 1 0 2 2 2 2 Nup133 N terminal like IKI3 PF04762.7 ETO31522.1 - 0.0088 13.9 0.0 0.057 11.2 0.0 2.2 1 1 0 2 2 2 1 IKI3 family DUF3601 PF12208.3 ETO31522.1 - 0.12 12.3 0.0 8.8 6.3 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF3601) WD40 PF00400.27 ETO31523.1 - 1.4e-67 221.3 25.4 1.6e-12 46.7 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO31523.1 - 1e-07 30.5 0.8 0.057 11.5 0.0 4.3 2 1 3 5 5 5 4 Nucleoporin Nup120/160 UPF0552 PF10574.4 ETO31523.1 - 0.025 14.0 1.4 0.042 13.3 1.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0552 MFS_1 PF07690.11 ETO31524.1 - 3.6e-21 75.2 32.4 1.6e-11 43.5 8.4 2.5 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.1 ETO31527.1 - 8.3 5.7 7.4 4.3 6.7 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF1675 PF07897.6 ETO31528.1 - 0.46 10.3 21.9 0.89 9.3 15.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Utp14 PF04615.8 ETO31528.1 - 0.57 8.2 25.6 0.67 8.0 17.8 1.1 1 0 0 1 1 1 0 Utp14 protein HCO3_cotransp PF00955.16 ETO31528.1 - 7 5.1 6.0 8.7 4.8 4.1 1.2 1 0 0 1 1 1 0 HCO3- transporter family Trypan_PARP PF05887.6 ETO31529.1 - 7.1 6.4 9.4 15 5.3 6.5 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Hom_end_hint PF05203.11 ETO31530.1 - 0.0043 16.8 3.6 0.0056 16.4 2.5 1.2 1 0 0 1 1 1 1 Hom_end-associated Hint Hydrolase_3 PF08282.7 ETO31530.1 - 0.0089 15.6 8.5 0.012 15.2 5.9 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Clp1 PF06807.9 ETO31530.1 - 0.37 10.5 2.6 0.85 9.3 1.8 1.6 1 1 0 1 1 1 0 Pre-mRNA cleavage complex II protein Clp1 TLP-20 PF06088.6 ETO31530.1 - 0.39 10.3 7.3 0.62 9.7 4.7 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Protocadherin PF08374.6 ETO31530.1 - 0.65 9.5 5.6 0.91 9.1 3.9 1.4 1 0 0 1 1 1 0 Protocadherin RasGEF_N PF00618.15 ETO31531.1 - 0.011 15.7 0.3 0.54 10.3 0.0 2.3 2 0 0 2 2 2 0 RasGEF N-terminal motif EST1 PF10374.4 ETO31531.1 - 0.073 13.0 0.0 0.16 11.9 0.0 1.5 1 1 0 1 1 1 0 Telomerase activating protein Est1 CobT PF06213.7 ETO31531.1 - 0.19 10.8 6.3 0.28 10.2 4.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.9 ETO31531.1 - 0.34 8.8 4.2 0.47 8.4 2.9 1.1 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.5 ETO31531.1 - 2.5 8.3 9.3 4.6 7.5 6.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-RING_2 PF13639.1 ETO31533.1 - 1e-12 47.6 4.5 1.7e-12 46.9 3.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 ETO31533.1 - 5.2e-08 32.4 2.4 8.9e-08 31.6 1.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO31533.1 - 4.8e-07 29.4 2.9 8e-07 28.6 2.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 ETO31533.1 - 6.1e-07 29.3 4.0 9.8e-07 28.7 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETO31533.1 - 9.1e-07 28.9 4.1 2.1e-06 27.7 2.8 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 ETO31533.1 - 2.8e-05 23.7 1.6 4e-05 23.1 1.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 ETO31533.1 - 6.1e-05 22.7 2.3 0.0001 22.0 1.6 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.24 ETO31533.1 - 0.0017 17.9 2.8 0.0031 17.1 1.9 1.4 1 0 0 1 1 1 1 PHD-finger RINGv PF12906.2 ETO31533.1 - 0.0085 16.1 2.6 0.018 15.0 1.8 1.6 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4_4 PF15227.1 ETO31533.1 - 0.051 13.4 2.2 0.12 12.2 1.5 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING BUD22 PF09073.5 ETO31533.1 - 0.078 12.0 5.4 0.11 11.5 3.7 1.3 1 0 0 1 1 1 0 BUD22 zf-RING-like PF08746.6 ETO31533.1 - 0.084 12.8 2.0 0.15 12.0 1.4 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 ETO31533.1 - 0.093 12.3 1.5 0.16 11.5 1.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.1 ETO31533.1 - 0.12 12.1 1.5 3.3 7.4 0.1 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_UBOX PF13445.1 ETO31533.1 - 0.16 11.6 3.4 0.54 10.0 0.1 2.6 2 0 0 2 2 2 0 RING-type zinc-finger Pex14_N PF04695.8 ETO31533.1 - 0.39 10.7 4.3 0.54 10.3 3.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region C1_1 PF00130.17 ETO31533.1 - 0.56 9.9 4.1 6.5 6.5 0.3 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FANCL_C PF11793.3 ETO31533.1 - 0.6 10.1 4.9 4.1 7.4 3.4 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-PHD-like PF15446.1 ETO31533.1 - 0.63 9.3 5.3 0.74 9.0 0.7 2.3 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Lin-8 PF03353.10 ETO31533.1 - 0.76 9.0 5.1 0.92 8.7 3.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.4 ETO31533.1 - 6.9 4.8 9.1 8 4.6 6.3 1.0 1 0 0 1 1 1 0 Transmembrane protein gag_pre-integrs PF13976.1 ETO31533.1 - 8.9 6.0 10.0 0.84 9.3 0.1 3.2 3 0 0 3 3 3 0 GAG-pre-integrase domain CAF-1_p150 PF11600.3 ETO31533.1 - 9.6 5.5 14.9 0.46 9.8 6.6 1.5 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal ORC3_N PF07034.6 ETO31534.1 - 0.0088 15.0 0.2 0.0088 15.0 0.2 1.4 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus INTS5_N PF14837.1 ETO31534.1 - 0.046 13.1 0.3 0.08 12.3 0.2 1.4 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus DB PF01682.14 ETO31534.1 - 0.11 12.5 6.6 0.067 13.2 3.2 1.6 1 1 1 2 2 2 0 DB module MU117 PF15474.1 ETO31534.1 - 0.14 12.6 2.3 0.31 11.5 1.6 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene family RNA_pol_Rpb1_5 PF04998.12 ETO31534.1 - 0.73 9.0 3.3 0.94 8.6 2.3 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 ORC3_N PF07034.6 ETO31535.1 - 5.2e-11 42.0 26.4 0.0031 16.5 1.8 4.3 2 2 0 4 4 4 4 Origin recognition complex (ORC) subunit 3 N-terminus TMEM154 PF15102.1 ETO31535.1 - 3.5 7.3 9.3 2.1 8.0 3.0 2.5 2 0 0 2 2 2 0 TMEM154 protein family Peptidase_S49_N PF08496.5 ETO31535.1 - 6.9 6.4 10.6 0.79 9.5 1.4 2.6 2 1 0 2 2 2 0 Peptidase family S49 N-terminal Flu_NP PF00506.13 ETO31536.1 - 0.026 13.0 6.0 0.029 12.8 4.2 1.1 1 0 0 1 1 1 0 Influenza virus nucleoprotein HALZ PF02183.13 ETO31537.1 - 0.024 14.3 0.8 0.024 14.3 0.5 4.1 3 1 1 4 4 4 0 Homeobox associated leucine zipper DUF1025 PF06262.6 ETO31537.1 - 0.065 13.0 1.0 6 6.7 0.1 2.5 2 0 0 2 2 2 0 Possibl zinc metallo-peptidase TMF_TATA_bd PF12325.3 ETO31537.1 - 0.41 10.3 23.6 0.04 13.6 9.2 3.1 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Kinesin-relat_1 PF12711.2 ETO31537.1 - 0.66 10.4 29.2 0.55 10.6 6.5 3.9 2 1 2 4 4 4 0 Kinesin motor DUF3895 PF13034.1 ETO31538.1 - 0.13 11.7 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3895) Ebola_NP PF05505.7 ETO31539.1 - 0.79 7.7 8.0 0.89 7.5 5.6 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein Menin PF05053.8 ETO31539.1 - 3.3 5.7 8.1 4.5 5.3 5.6 1.3 1 0 0 1 1 1 0 Menin RasGEF PF00617.14 ETO31542.1 - 1.6e-30 106.2 0.6 5.1e-30 104.6 0.2 1.7 1 1 1 2 2 2 1 RasGEF domain Vps51 PF08700.6 ETO31542.1 - 0.23 11.3 1.3 0.57 10.0 0.1 2.2 2 1 0 2 2 2 0 Vps51/Vps67 Metallophos PF00149.23 ETO31543.1 - 4.1e-34 117.7 0.2 1.1e-33 116.3 0.1 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase v110 PF01639.12 ETO31543.1 - 0.00051 19.5 0.7 0.00085 18.8 0.5 1.3 1 0 0 1 1 1 1 Viral family 110 U-box PF04564.10 ETO31544.1 - 1.4e-12 47.3 0.1 6.5e-12 45.2 0.0 2.2 2 0 0 2 2 2 1 U-box domain zf-Nse PF11789.3 ETO31544.1 - 1.6e-05 24.3 0.0 3.7e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 ETO31544.1 - 0.0011 18.6 0.0 0.0033 17.1 0.0 1.9 1 0 0 1 1 1 1 RING-type zinc-finger MMR_HSR1 PF01926.18 ETO31544.1 - 0.0015 18.4 0.0 0.0047 16.8 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase zf-C3HC4_4 PF15227.1 ETO31544.1 - 0.0028 17.5 0.0 0.0071 16.2 0.0 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING ABC_tran PF00005.22 ETO31544.1 - 0.0028 17.9 0.0 0.011 16.0 0.0 2.0 1 0 0 1 1 1 1 ABC transporter AAA_14 PF13173.1 ETO31544.1 - 0.011 15.6 0.0 0.036 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 ETO31544.1 - 0.018 14.2 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Myosin_head PF00063.16 ETO31546.1 - 1.7e-15 56.1 0.0 1.7e-15 56.1 0.0 2.8 2 1 1 3 3 3 1 Myosin head (motor domain) Myosin_head PF00063.16 ETO31547.1 - 3.9e-77 259.8 1.1 4.8e-77 259.5 0.7 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) PH PF00169.24 ETO31550.1 - 1.4e-07 31.6 10.1 7.6e-07 29.2 0.0 3.6 3 1 0 3 3 3 1 PH domain PX PF00787.19 ETO31550.1 - 6.7e-05 22.6 0.1 6.7e-05 22.6 0.1 2.4 3 0 0 3 3 3 1 PX domain PH_2 PF08458.5 ETO31550.1 - 0.0016 18.3 0.0 0.0051 16.7 0.0 1.8 1 0 0 1 1 1 1 Plant pleckstrin homology-like region PH_8 PF15409.1 ETO31550.1 - 0.0096 15.9 0.1 0.11 12.5 0.0 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain TEX12 PF15219.1 ETO31550.1 - 0.067 13.1 4.0 0.17 11.8 2.8 1.8 1 0 0 1 1 1 0 Testis-expressed 12 MCC-bdg_PDZ PF10506.4 ETO31550.1 - 0.54 10.1 17.0 0.11 12.2 1.6 3.5 3 1 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Atg14 PF10186.4 ETO31550.1 - 0.68 8.8 26.7 1.2 8.0 18.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PH_11 PF15413.1 ETO31550.1 - 2.5 8.3 12.1 0.16 12.2 0.3 4.2 4 2 0 4 4 4 0 Pleckstrin homology domain IncA PF04156.9 ETO31550.1 - 3 7.3 40.6 0.77 9.3 18.3 2.4 1 1 1 2 2 2 0 IncA protein DUF4407 PF14362.1 ETO31550.1 - 7.1 5.4 23.6 1.7 7.5 10.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) CwfJ_C_1 PF04677.10 ETO31551.1 - 7.3e-29 99.8 0.0 1.6e-28 98.8 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 ETO31551.1 - 7.6e-12 45.5 0.2 5.4e-11 42.8 0.0 2.4 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 zf-CCHC PF00098.18 ETO31551.1 - 0.0018 18.1 1.5 0.0018 18.1 1.0 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.1 ETO31551.1 - 0.013 14.9 5.7 0.013 14.9 4.0 2.1 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.1 ETO31551.1 - 0.021 14.5 0.2 0.051 13.3 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle MutS_IV PF05190.13 ETO31551.1 - 0.067 13.3 1.2 0.18 12.0 0.9 1.7 1 0 0 1 1 1 0 MutS family domain IV Ribosomal_60s PF00428.14 ETO31552.1 - 0.0052 17.1 2.2 0.0052 17.1 1.5 4.0 6 0 0 6 6 6 1 60s Acidic ribosomal protein VWA_3 PF13768.1 ETO31552.1 - 0.048 13.3 0.1 0.26 10.9 0.0 2.3 2 0 0 2 2 2 0 von Willebrand factor type A domain Zip PF02535.17 ETO31552.1 - 1.9 7.4 9.3 0.17 10.8 0.1 3.1 3 0 0 3 3 3 0 ZIP Zinc transporter AAA PF00004.24 ETO31553.1 - 1.1e-42 145.3 0.0 2.6e-42 144.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETO31553.1 - 1e-06 28.5 0.1 3.4e-05 23.5 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 ETO31553.1 - 1.7e-06 28.0 0.0 5.7e-06 26.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 ETO31553.1 - 4.9e-06 25.7 0.0 1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 ETO31553.1 - 7.9e-06 25.9 0.0 0.0001 22.3 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 ETO31553.1 - 3.4e-05 24.0 0.4 0.0015 18.6 0.0 2.9 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.8 ETO31553.1 - 0.00029 19.8 0.0 0.00063 18.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 ETO31553.1 - 0.00045 21.0 0.1 0.0013 19.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 ETO31553.1 - 0.00057 19.3 0.4 0.0028 17.0 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_3 PF07726.6 ETO31553.1 - 0.0026 17.3 0.0 0.0074 15.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 ETO31553.1 - 0.0031 17.2 0.1 0.0067 16.1 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Sigma54_activat PF00158.21 ETO31553.1 - 0.0042 16.5 0.0 0.03 13.8 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 ETO31553.1 - 0.0043 16.2 0.1 0.0086 15.2 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 ETO31553.1 - 0.0049 17.0 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Parvo_NS1 PF01057.12 ETO31553.1 - 0.0051 15.7 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 TIP49 PF06068.8 ETO31553.1 - 0.0059 15.3 0.0 0.016 13.9 0.0 1.7 1 0 0 1 1 1 1 TIP49 C-terminus Zeta_toxin PF06414.7 ETO31553.1 - 0.0085 15.2 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 ETO31553.1 - 0.0087 15.9 0.0 0.024 14.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 ETO31553.1 - 0.011 15.3 0.7 0.02 14.4 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 ETO31553.1 - 0.014 15.2 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 ETO31553.1 - 0.015 15.6 0.0 0.05 13.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 ETO31553.1 - 0.017 14.5 0.4 0.1 11.9 0.1 2.3 2 1 1 3 3 3 0 AAA domain AAA_28 PF13521.1 ETO31553.1 - 0.019 14.9 0.0 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 ETO31553.1 - 0.024 13.8 0.0 0.049 12.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein UPF0079 PF02367.12 ETO31553.1 - 0.024 14.2 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 ETO31553.1 - 0.029 14.0 0.0 0.44 10.1 0.0 2.8 1 1 2 3 3 3 0 Archaeal ATPase NACHT PF05729.7 ETO31553.1 - 0.041 13.5 0.1 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.1 ETO31553.1 - 0.055 13.5 0.0 0.22 11.5 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain KaiC PF06745.8 ETO31553.1 - 0.064 12.3 1.1 0.16 11.0 0.0 2.2 3 0 0 3 3 2 0 KaiC PIF1 PF05970.9 ETO31553.1 - 0.077 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase eIF-1a PF01176.14 ETO31553.1 - 0.086 12.2 0.1 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 ABC_tran PF00005.22 ETO31553.1 - 0.12 12.6 0.3 0.62 10.3 0.0 2.2 2 1 0 2 2 1 0 ABC transporter GKAP PF03359.8 ETO31554.1 - 0.044 13.3 1.0 0.051 13.1 0.7 1.0 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein WD40 PF00400.27 ETO31555.1 - 1.9e-19 68.7 7.5 1e-08 34.7 0.7 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF3019 PF11456.3 ETO31555.1 - 5.1 7.4 6.9 5 7.5 0.1 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3019) UCH PF00443.24 ETO31556.1 - 1.7e-67 227.3 17.4 1.7e-67 227.3 12.0 3.7 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO31556.1 - 2.9e-12 46.6 36.6 5.6e-11 42.4 11.8 3.9 2 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase GAGA_bind PF06217.7 ETO31556.1 - 1.1 9.1 22.0 0.019 14.9 5.3 2.7 3 0 0 3 3 3 0 GAGA binding protein-like family DUF3987 PF13148.1 ETO31556.1 - 1.3 7.5 7.7 2 6.8 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) RP-C_C PF11800.3 ETO31556.1 - 1.7 8.2 13.2 2.7 7.6 1.5 3.0 3 0 0 3 3 3 0 Replication protein C C-terminal region Zip PF02535.17 ETO31556.1 - 2.6 6.9 7.8 0.46 9.4 0.5 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Folate_carrier PF01770.13 ETO31556.1 - 8.6 4.7 10.7 0.35 9.3 1.8 2.2 2 0 0 2 2 2 0 Reduced folate carrier PBP_sp32 PF07222.7 ETO31556.1 - 9.8 5.2 17.1 0.17 11.0 5.9 2.5 2 0 0 2 2 2 0 Proacrosin binding protein sp32 Mad3_BUB1_I PF08311.7 ETO31557.1 - 0.0011 18.8 1.5 0.0034 17.1 1.0 1.9 1 1 0 1 1 1 1 Mad3/BUB1 homology region 1 MutS_II PF05188.12 ETO31557.1 - 0.06 13.4 0.0 0.32 11.0 0.0 2.2 2 0 0 2 2 2 0 MutS domain II DUF1528 PF07515.6 ETO31558.1 - 0.029 14.4 1.2 1 9.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1528) InvH PF04741.7 ETO31558.1 - 0.13 12.1 1.1 0.22 11.3 0.7 1.4 1 1 0 1 1 1 0 InvH outer membrane lipoprotein DUF2603 PF10788.4 ETO31558.1 - 0.2 11.4 2.2 1.3 8.7 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2603) DUF3661 PF12400.3 ETO31559.1 - 0.023 14.7 1.0 0.023 14.7 0.7 1.7 2 0 0 2 2 2 0 Vaculolar membrane protein 5_nucleotid PF05761.9 ETO31562.1 - 0.012 14.2 1.2 0.017 13.6 0.8 1.3 1 0 0 1 1 1 0 5' nucleotidase family SAM_2 PF07647.12 ETO31562.1 - 0.018 14.8 2.4 1.2 9.0 0.1 2.9 2 1 1 3 3 3 0 SAM domain (Sterile alpha motif) HIT PF01230.18 ETO31562.1 - 0.022 15.2 0.7 16 6.0 0.0 2.9 3 0 0 3 3 3 0 HIT domain KxDL PF10241.4 ETO31562.1 - 0.034 14.0 0.7 0.034 14.0 0.5 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein TMF_TATA_bd PF12325.3 ETO31562.1 - 0.036 13.7 7.4 0.55 9.9 5.1 2.2 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Atg14 PF10186.4 ETO31562.1 - 0.066 12.1 3.6 0.091 11.6 2.5 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ATG16 PF08614.6 ETO31562.1 - 0.079 12.7 8.7 0.017 14.9 3.7 1.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) ALMT PF11744.3 ETO31562.1 - 0.17 10.4 1.9 0.22 10.1 1.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter GrpE PF01025.14 ETO31562.1 - 0.24 10.9 4.3 0.44 10.0 3.0 1.4 1 0 0 1 1 1 0 GrpE DUF948 PF06103.6 ETO31562.1 - 0.31 10.9 3.0 0.47 10.3 0.5 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 ETO31562.1 - 0.48 9.9 8.6 2 7.9 5.7 1.9 1 1 0 1 1 1 0 IncA protein Synaptobrevin PF00957.16 ETO31562.1 - 0.58 9.7 4.5 3.1 7.4 2.0 2.6 1 1 1 2 2 2 0 Synaptobrevin TPR_MLP1_2 PF07926.7 ETO31562.1 - 0.82 9.4 8.9 1.9 8.2 6.2 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.6 ETO31562.1 - 0.89 9.4 3.5 1.6 8.6 0.1 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.15 ETO31562.1 - 3.4 7.4 10.6 0.95 9.2 1.6 2.8 2 1 1 3 3 3 0 Prefoldin subunit AKNA PF12443.3 ETO31562.1 - 3.9 7.5 7.6 2.4 8.2 0.4 2.5 1 1 1 2 2 2 0 AT-hook-containing transcription factor Ank PF00023.25 ETO31563.1 - 0.0016 18.1 0.3 0.53 10.1 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat FixQ PF05545.6 ETO31563.1 - 0.22 11.1 0.1 0.22 11.1 0.0 2.1 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Transgly PF00912.17 ETO31565.1 - 0.011 15.0 1.3 0.02 14.2 0.9 1.3 1 0 0 1 1 1 0 Transglycosylase MbeD_MobD PF04899.7 ETO31565.1 - 0.71 9.8 3.7 0.63 9.9 1.3 1.8 2 0 0 2 2 2 0 MbeD/MobD like PHD PF00628.24 ETO31566.1 - 1.4e-07 31.0 2.6 4.6e-07 29.4 1.8 1.9 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 ETO31566.1 - 0.0032 17.5 3.2 0.0086 16.1 1.8 2.1 1 1 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 ETO31566.1 - 0.0055 16.6 3.2 0.024 14.6 1.5 2.4 1 1 1 2 2 2 1 PHD-zinc-finger like domain PHD_2 PF13831.1 ETO31566.1 - 0.017 14.4 0.8 0.031 13.5 0.0 1.8 2 0 0 2 2 2 0 PHD-finger NACHT PF05729.7 ETO31567.1 - 2.6e-08 33.6 0.0 5.6e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO31567.1 - 0.00024 21.4 0.1 0.00024 21.4 0.1 5.0 4 1 3 7 7 7 1 AAA domain AAA_17 PF13207.1 ETO31567.1 - 0.0026 18.5 4.3 0.0042 17.8 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.1 ETO31567.1 - 0.0034 17.5 1.5 0.0087 16.1 0.1 2.5 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 ETO31567.1 - 0.0089 16.3 0.1 0.0089 16.3 0.0 2.9 3 0 0 3 3 3 1 ABC transporter AAA_16 PF13191.1 ETO31567.1 - 0.13 12.2 0.0 0.88 9.5 0.0 2.4 2 1 1 3 3 3 0 AAA ATPase domain RPA_interact_N PF14766.1 ETO31570.1 - 0.09 12.2 1.0 0.18 11.3 0.7 1.5 1 0 0 1 1 1 0 Replication protein A interacting N-terminal zf-H2C2_2 PF13465.1 ETO31570.1 - 4 7.9 5.7 12 6.4 0.4 2.4 1 1 1 2 2 2 0 Zinc-finger double domain TraB PF01963.12 ETO31571.1 - 4.4e-07 29.6 0.0 4.8e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 TraB family Corona_6B_7B PF03262.8 ETO31571.1 - 0.032 13.4 1.8 0.047 12.9 1.2 1.2 1 0 0 1 1 1 0 Coronavirus 6B/7B protein Pox_polyA_pol_N PF12630.2 ETO31571.1 - 0.58 10.2 14.7 0.26 11.3 4.9 2.8 1 1 2 3 3 3 0 Poxvirus poly(A) polymerase N-terminal domain Adaptin_N PF01602.15 ETO31572.1 - 0.022 13.1 1.3 0.026 12.8 0.9 1.0 1 0 0 1 1 1 0 Adaptin N terminal region DisA-linker PF10635.4 ETO31572.1 - 0.041 13.3 2.3 0.05 13.1 1.6 1.2 1 0 0 1 1 1 0 DisA bacterial checkpoint controller linker region DUF2703 PF10865.3 ETO31572.1 - 0.055 13.4 2.5 0.19 11.6 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF2703) ATP-synt_B PF00430.13 ETO31572.1 - 1.9 8.3 13.0 2.3 8.0 9.0 1.0 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) CBF_beta PF02312.12 ETO31572.1 - 5.5 6.5 8.3 0.77 9.3 1.8 1.9 1 1 1 2 2 2 0 Core binding factor beta subunit IncA PF04156.9 ETO31572.1 - 6.6 6.2 9.9 8.4 5.9 6.9 1.2 1 0 0 1 1 1 0 IncA protein Pkinase PF00069.20 ETO31573.1 - 7.3e-54 182.6 0.1 1.1e-53 182.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO31573.1 - 1e-29 103.4 0.0 1.6e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO31573.1 - 7.2e-05 21.8 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 ETO31573.1 - 0.0037 16.6 3.6 0.039 13.2 0.1 2.3 2 0 0 2 2 2 1 RIO1 family ASCH PF04266.9 ETO31573.1 - 0.0086 16.4 0.4 5.8 7.3 0.0 2.3 2 0 0 2 2 2 2 ASCH domain APH PF01636.18 ETO31573.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PRT_C PF08372.5 ETO31575.1 - 0.03 13.8 1.0 0.052 13.0 0.7 1.3 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal CASP_C PF08172.7 ETO31577.1 - 0.0014 17.7 15.6 0.0022 17.0 10.8 1.3 1 0 0 1 1 1 1 CASP C terminal Shugoshin_N PF07558.6 ETO31577.1 - 0.0036 16.9 9.9 0.0036 16.9 6.9 2.2 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region HALZ PF02183.13 ETO31577.1 - 0.0049 16.5 3.0 0.0049 16.5 2.1 3.8 2 2 1 3 3 3 2 Homeobox associated leucine zipper IncA PF04156.9 ETO31577.1 - 0.0059 16.2 24.0 0.029 13.9 3.5 2.2 1 1 0 2 2 2 2 IncA protein DUF948 PF06103.6 ETO31577.1 - 0.0091 15.8 11.8 0.1 12.4 2.3 2.5 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF948) Rab5-bind PF09311.6 ETO31577.1 - 0.013 15.4 8.4 0.013 15.4 5.8 2.5 2 1 0 2 2 2 0 Rabaptin-like protein DivIC PF04977.10 ETO31577.1 - 0.015 14.7 8.1 0.015 14.7 5.6 3.0 2 1 0 2 2 2 0 Septum formation initiator Fis1_TPR_C PF14853.1 ETO31577.1 - 0.062 13.1 4.9 0.12 12.2 0.1 2.9 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat AAA_13 PF13166.1 ETO31577.1 - 0.094 11.1 19.8 0.12 10.8 13.7 1.1 1 0 0 1 1 1 0 AAA domain FlxA PF14282.1 ETO31577.1 - 0.1 12.5 23.8 0.61 10.0 7.5 2.7 2 0 0 2 2 2 0 FlxA-like protein CENP-F_leu_zip PF10473.4 ETO31577.1 - 0.13 12.1 23.8 0.041 13.7 6.9 2.4 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.6 ETO31577.1 - 0.25 11.1 26.8 1.3 8.8 9.8 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Prefoldin PF02996.12 ETO31577.1 - 0.36 10.5 14.9 0.51 10.0 2.9 2.8 2 0 0 2 2 2 0 Prefoldin subunit DUF3391 PF11871.3 ETO31577.1 - 0.68 10.1 7.0 0.4 10.8 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF2353 PF09789.4 ETO31577.1 - 1 8.5 21.4 0.74 9.0 1.7 2.2 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) TBPIP PF07106.8 ETO31577.1 - 1.2 8.6 23.8 1.1 8.7 5.9 2.4 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) APG6 PF04111.7 ETO31577.1 - 1.2 8.0 26.3 1.1 8.2 7.8 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 TMF_TATA_bd PF12325.3 ETO31577.1 - 1.4 8.6 23.3 1.2 8.8 3.7 3.0 1 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.3 ETO31577.1 - 1.7 8.4 28.8 1.3 8.8 7.7 2.5 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding WXG100 PF06013.7 ETO31577.1 - 2.1 8.3 14.6 3.1 7.8 2.4 3.1 3 1 0 3 3 2 0 Proteins of 100 residues with WXG UPF0449 PF15136.1 ETO31577.1 - 2.5 8.3 15.7 5.5 7.2 2.2 3.1 2 1 1 3 3 3 0 Uncharacterised protein family UPF0449 Striatin PF08232.7 ETO31577.1 - 3.1 8.1 18.2 0.16 12.3 3.2 2.5 2 1 0 2 2 2 0 Striatin family bZIP_1 PF00170.16 ETO31577.1 - 3.8 7.5 14.5 0.31 11.0 4.6 3.0 2 2 1 3 3 3 0 bZIP transcription factor Tropomyosin_1 PF12718.2 ETO31577.1 - 3.9 7.2 24.8 2.4 7.9 6.2 2.4 1 1 1 2 2 2 0 Tropomyosin like TMF_DNA_bd PF12329.3 ETO31577.1 - 5.3 6.9 22.2 0.85 9.4 7.2 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 ETO31577.1 - 5.6 7.3 23.0 3 8.2 5.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF4140 PF13600.1 ETO31577.1 - 7.5 7.0 11.5 2.3 8.6 1.7 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF3847 PF12958.2 ETO31577.1 - 8 6.3 19.4 10 5.9 4.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3847) TPR_MLP1_2 PF07926.7 ETO31577.1 - 8.3 6.1 29.3 0.99 9.1 5.1 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2968 PF11180.3 ETO31577.1 - 9.9 5.4 24.8 6.3 6.1 7.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) MAD PF05557.8 ETO31578.1 - 1.7e-17 62.8 1.1 2.9e-17 62.0 0.8 1.3 1 1 0 1 1 1 1 Mitotic checkpoint protein HOOK PF05622.7 ETO31578.1 - 0.00026 18.9 1.0 0.00036 18.4 0.7 1.2 1 0 0 1 1 1 1 HOOK protein bZIP_1 PF00170.16 ETO31578.1 - 0.0021 17.9 0.5 0.0021 17.9 0.4 2.9 3 1 0 3 3 2 1 bZIP transcription factor FlxA PF14282.1 ETO31578.1 - 0.0084 16.0 0.9 0.021 14.7 0.6 1.7 1 0 0 1 1 1 1 FlxA-like protein Shugoshin_N PF07558.6 ETO31578.1 - 0.021 14.5 0.5 0.063 12.9 0.1 2.1 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Rootletin PF15035.1 ETO31578.1 - 0.022 14.7 3.5 0.044 13.7 2.4 1.5 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Spc7 PF08317.6 ETO31578.1 - 0.031 12.9 6.1 0.04 12.5 4.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.7 ETO31578.1 - 0.04 13.6 4.3 0.055 13.2 2.4 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Mnd1 PF03962.10 ETO31578.1 - 0.048 13.3 2.7 0.069 12.8 1.8 1.4 1 0 0 1 1 1 0 Mnd1 family FlaC_arch PF05377.6 ETO31578.1 - 0.056 13.3 2.4 3.1 7.7 0.1 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) APG17 PF04108.7 ETO31578.1 - 0.06 12.1 3.6 0.071 11.8 2.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 Cep57_MT_bd PF06657.8 ETO31578.1 - 0.072 13.0 2.4 0.098 12.6 0.6 2.1 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF641 PF04859.7 ETO31578.1 - 0.073 12.8 2.2 0.13 12.0 1.2 1.7 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF2408 PF10303.4 ETO31578.1 - 0.075 13.1 3.7 0.051 13.6 1.5 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF2408) GAS PF13851.1 ETO31578.1 - 0.09 11.9 10.6 0.16 11.1 7.3 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.4 ETO31578.1 - 0.11 11.4 4.0 0.18 10.7 2.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HALZ PF02183.13 ETO31578.1 - 0.19 11.4 3.9 5.1 6.9 0.3 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper ADIP PF11559.3 ETO31578.1 - 0.23 11.3 5.5 0.39 10.6 3.8 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 ETO31578.1 - 0.32 10.5 5.7 0.29 10.7 1.3 2.2 1 1 2 3 3 3 0 IncA protein bZIP_2 PF07716.10 ETO31578.1 - 0.53 10.1 5.5 1.5 8.7 0.1 3.3 3 0 0 3 3 3 0 Basic region leucine zipper DivIVA PF05103.8 ETO31578.1 - 1.4 8.9 6.2 5.3 7.1 0.3 2.9 1 1 2 3 3 3 0 DivIVA protein Ax_dynein_light PF10211.4 ETO31578.1 - 1.6 8.5 7.0 11 5.7 1.7 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain Spc24 PF08286.6 ETO31578.1 - 5.2 6.8 8.6 0.74 9.5 0.6 2.6 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 WD40 PF00400.27 ETO31580.1 - 2.6e-35 119.0 11.1 1.4e-11 43.7 0.3 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO31580.1 - 1.5e-08 33.2 0.8 0.00015 20.0 0.1 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 BSP_II PF05432.6 ETO31581.1 - 3 7.0 8.9 0.35 10.1 0.5 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) TIP_N PF12457.3 ETO31581.1 - 3.3 7.8 10.9 2.5 8.1 1.7 2.7 3 0 0 3 3 3 0 Tuftelin interacting protein N terminal Pkinase PF00069.20 ETO31583.1 - 1.2e-05 24.6 0.0 1.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 ETO31584.1 - 1.4e-18 66.9 0.1 1.5e-18 66.8 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO31584.1 - 1.8e-13 50.1 0.1 2e-13 50.0 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase DNA_methylase PF00145.12 ETO31585.1 - 1.7e-39 135.8 0.0 2.7e-39 135.2 0.0 1.3 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase Piwi PF02171.12 ETO31586.1 - 2.5e-29 102.2 0.9 1.8e-24 86.2 0.6 2.3 2 1 0 2 2 2 2 Piwi domain SAE2 PF08573.5 ETO31586.1 - 7.5 7.3 9.5 2.7 8.7 0.9 2.4 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus AF1Q PF15017.1 ETO31586.1 - 8.2 6.4 12.3 2.8 7.9 1.1 2.5 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator Phosphoesterase PF04185.9 ETO31587.1 - 1.3e-50 172.6 0.0 4.1e-49 167.7 0.0 2.7 1 1 0 1 1 1 1 Phosphoesterase family RGS PF00615.14 ETO31588.1 - 0.01 15.9 0.1 0.16 12.0 0.0 2.4 2 1 0 2 2 2 0 Regulator of G protein signaling domain Caveolin PF01146.12 ETO31588.1 - 0.31 10.6 5.5 0.66 9.5 3.8 1.5 1 0 0 1 1 1 0 Caveolin ParBc_2 PF08857.6 ETO31589.1 - 1.3e-31 109.5 0.1 2.5e-31 108.7 0.1 1.5 1 0 0 1 1 1 1 Putative ParB-like nuclease DUF3753 PF12575.3 ETO31589.1 - 5.9 6.7 6.6 29 4.5 0.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3753) RRM_1 PF00076.17 ETO31590.1 - 8e-25 86.2 0.2 5.8e-15 54.6 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO31590.1 - 2.1e-22 78.8 0.1 7.1e-13 48.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO31590.1 - 4.7e-08 32.7 0.9 4.8e-07 29.5 0.1 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETO31590.1 - 2.7e-07 30.2 0.3 0.0014 18.3 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DUF4651 PF15513.1 ETO31590.1 - 9.2e-05 21.8 0.1 0.81 9.1 0.0 3.1 2 1 1 3 3 3 2 Domain of unknown function (DUF4651) DUF1699 PF08004.6 ETO31590.1 - 0.056 12.9 0.2 3.1 7.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1699) TFIIB PF00382.14 ETO31592.1 - 4.7e-22 77.5 0.0 1.4e-10 40.7 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat RB_B PF01857.15 ETO31592.1 - 0.062 12.8 0.5 0.12 11.8 0.3 1.5 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain DUF2201_N PF13203.1 ETO31593.1 - 0.0023 17.1 3.7 0.0025 17.0 2.5 1.1 1 0 0 1 1 1 1 Putative metallopeptidase domain DUF1510 PF07423.6 ETO31593.1 - 0.0034 16.7 13.3 0.005 16.2 9.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) FancD2 PF14631.1 ETO31593.1 - 0.018 12.1 9.7 0.023 11.8 6.8 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease SR-25 PF10500.4 ETO31593.1 - 0.055 12.9 19.7 0.09 12.2 13.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TATR PF03430.8 ETO31593.1 - 0.12 10.9 9.5 0.15 10.6 6.6 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Nucleo_P87 PF07267.6 ETO31593.1 - 0.29 9.7 7.4 0.34 9.5 5.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF601 PF04642.7 ETO31593.1 - 0.39 10.0 17.1 0.058 12.7 9.4 1.4 2 0 0 2 2 2 0 Protein of unknown function, DUF601 TFIIF_alpha PF05793.7 ETO31593.1 - 0.42 8.9 28.3 0.61 8.4 19.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GAGA_bind PF06217.7 ETO31593.1 - 0.58 10.0 9.2 0.7 9.7 6.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Rtf2 PF04641.7 ETO31593.1 - 0.76 8.9 16.1 1.2 8.2 11.2 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger DUF3827 PF12877.2 ETO31593.1 - 0.82 7.6 7.7 1 7.3 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Pox_Ag35 PF03286.9 ETO31593.1 - 1.6 8.1 18.7 2.8 7.4 12.9 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DDHD PF02862.12 ETO31593.1 - 2.2 8.0 6.6 3.2 7.4 4.6 1.2 1 0 0 1 1 1 0 DDHD domain NARP1 PF12569.3 ETO31593.1 - 2.8 6.5 14.3 4.4 5.9 9.9 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF382 PF04037.8 ETO31593.1 - 3 7.6 7.5 18 5.1 4.5 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF382) RNA_pol_3_Rpc31 PF11705.3 ETO31593.1 - 3.5 7.5 21.7 6.2 6.6 15.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 U79_P34 PF03064.11 ETO31593.1 - 5.6 6.4 19.3 8.4 5.8 13.4 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 TLD PF07534.11 ETO31594.1 - 3.9e-17 62.5 1.9 5.9e-17 61.9 1.3 1.2 1 0 0 1 1 1 1 TLD DUF995 PF06191.7 ETO31594.1 - 0.067 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF995) Condensin2nSMC PF12422.3 ETO31594.1 - 0.084 12.6 0.1 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit HSP70 PF00012.15 ETO31595.1 - 0.0055 14.6 0.4 0.071 11.0 0.0 2.0 1 1 1 2 2 2 2 Hsp70 protein Kelch_6 PF13964.1 ETO31596.1 - 2.8e-08 33.5 3.5 0.045 13.9 0.1 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO31596.1 - 3.6e-07 29.7 3.9 0.0069 16.1 0.5 4.3 4 1 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO31596.1 - 4.9e-06 25.9 2.6 0.39 10.3 0.6 4.6 4 1 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO31596.1 - 9e-05 22.1 1.4 0.014 15.1 0.1 3.5 3 1 1 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO31596.1 - 0.00056 19.8 2.9 1.2 9.2 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO31596.1 - 0.011 15.9 0.6 0.67 10.1 0.0 4.0 6 0 0 6 6 6 0 Galactose oxidase, central domain Peptidase_M48 PF01435.13 ETO31597.1 - 7.4e-16 58.3 0.0 1.1e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Pex14_N PF04695.8 ETO31597.1 - 0.18 11.8 7.2 1.2 9.1 0.2 3.1 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF605 PF04652.11 ETO31598.1 - 0.051 12.9 12.4 0.061 12.7 8.6 1.1 1 0 0 1 1 1 0 Vta1 like DUF1675 PF07897.6 ETO31598.1 - 0.055 13.3 13.9 0.066 13.0 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) ATP11 PF06644.6 ETO31598.1 - 0.063 12.7 14.9 0.078 12.4 10.3 1.0 1 0 0 1 1 1 0 ATP11 protein Merozoite_SPAM PF07133.6 ETO31598.1 - 0.1 12.4 24.2 0.16 11.8 16.8 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Hid1 PF12722.2 ETO31598.1 - 0.14 9.8 17.0 0.15 9.6 11.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein G-7-MTase PF12803.2 ETO31598.1 - 0.41 9.7 5.9 0.49 9.4 4.1 1.1 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) Pox_Ag35 PF03286.9 ETO31598.1 - 0.9 9.0 18.8 3.6 7.0 0.0 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Pex14_N PF04695.8 ETO31598.1 - 0.93 9.5 10.9 1.2 9.2 7.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.4 ETO31598.1 - 1.1 7.4 21.9 1.2 7.2 15.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 ETO31598.1 - 1.4 8.6 14.0 1.6 8.4 9.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Fungal_trans_2 PF11951.3 ETO31598.1 - 1.4 7.4 12.1 2.4 6.6 4.7 2.1 1 1 1 2 2 2 0 Fungal specific transcription factor domain SpoIIIAH PF12685.2 ETO31598.1 - 1.4 8.3 18.0 1.8 7.9 12.5 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Zip PF02535.17 ETO31598.1 - 1.6 7.6 9.1 2 7.3 6.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4045 PF13254.1 ETO31598.1 - 1.7 7.8 15.0 2.1 7.5 10.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CDC45 PF02724.9 ETO31598.1 - 1.9 6.4 19.3 2.2 6.2 13.4 1.1 1 0 0 1 1 1 0 CDC45-like protein RNase_H2_suC PF08615.6 ETO31598.1 - 2.1 8.2 14.3 33 4.3 9.9 2.0 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Otopetrin PF03189.8 ETO31598.1 - 3.5 6.5 5.2 4.1 6.2 3.6 1.2 1 0 0 1 1 1 0 Otopetrin DUF3128 PF11326.3 ETO31598.1 - 4.1 7.5 21.2 0.066 13.3 1.5 2.9 1 1 1 2 2 1 0 Protein of unknown function (DUF3128) DUF2146 PF10220.4 ETO31598.1 - 4.4 5.1 15.2 5.3 4.8 10.6 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) AUX_IAA PF02309.11 ETO31598.1 - 4.5 6.9 13.1 5.9 6.5 9.0 1.2 1 0 0 1 1 1 0 AUX/IAA family FHIPEP PF00771.15 ETO31598.1 - 4.7 5.4 7.0 6.2 5.0 4.8 1.3 1 0 0 1 1 1 0 FHIPEP family Lin-8 PF03353.10 ETO31598.1 - 5.5 6.1 22.6 6.6 5.9 15.7 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4544 PF15077.1 ETO31598.1 - 5.8 6.3 9.2 7.9 5.9 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) RNA_pol_Rpb1_5 PF04998.12 ETO31598.1 - 7.1 5.7 9.3 8.3 5.5 6.4 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Kei1 PF08552.6 ETO31598.1 - 7.5 6.1 6.5 9.1 5.8 4.5 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 AvrE PF11725.3 ETO31598.1 - 9.8 3.0 14.2 11 2.9 9.9 1.0 1 0 0 1 1 1 0 Pathogenicity factor Pox_A11 PF05061.8 ETO31599.1 - 0.31 10.0 1.7 0.49 9.4 1.2 1.2 1 0 0 1 1 1 0 Poxvirus A11 Protein DUF2197 PF09963.4 ETO31601.1 - 0.064 13.2 0.0 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) MerR-DNA-bind PF09278.6 ETO31602.1 - 0.3 11.5 5.8 1.9 8.9 0.2 2.5 2 0 0 2 2 2 0 MerR, DNA binding HTH_44 PF14641.1 ETO31603.1 - 9.4e-11 41.7 3.9 2.7e-10 40.2 2.7 1.8 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 DUF3474 PF11960.3 ETO31603.1 - 3.5 7.6 7.7 12 5.9 5.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) Pkinase PF00069.20 ETO31604.1 - 8.2e-20 71.0 0.2 8e-13 48.1 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO31604.1 - 3.5e-08 32.8 0.3 2.5e-06 26.7 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 ETO31604.1 - 3.7e-05 22.8 0.1 6.3e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO31604.1 - 0.039 13.6 0.1 0.069 12.8 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 ETO31604.1 - 0.056 13.0 0.9 0.1 12.1 0.6 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase SSP160 PF06933.6 ETO31604.1 - 0.21 9.5 8.5 0.39 8.6 5.9 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Peptidase_C14 PF00656.17 ETO31606.1 - 6.8e-12 45.6 0.4 1.1e-11 44.9 0.2 1.3 1 0 0 1 1 1 1 Caspase domain AAA_assoc_C PF09821.4 ETO31606.1 - 0.19 12.0 2.4 1.9 8.7 0.3 2.3 2 0 0 2 2 2 0 C-terminal AAA-associated domain NblA PF04485.7 ETO31606.1 - 0.23 11.3 4.7 0.084 12.7 0.8 2.0 2 0 0 2 2 2 0 Phycobilisome degradation protein nblA WD40 PF00400.27 ETO31607.1 - 5.8e-59 193.9 26.1 4.5e-10 39.0 0.3 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO31607.1 - 2.1e-07 29.4 16.1 7.7e-05 21.0 0.1 5.7 2 1 1 5 5 5 4 Nucleoporin Nup120/160 NMN_transporter PF04973.7 ETO31607.1 - 0.1 12.0 2.9 0.24 10.8 2.0 1.6 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter WD40 PF00400.27 ETO31609.1 - 7e-59 193.7 31.6 8e-11 41.3 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO31609.1 - 5.9e-09 34.6 6.8 0.037 12.1 0.0 5.1 1 1 2 4 4 4 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO31609.1 - 0.024 14.0 0.1 1.9 7.8 0.0 2.6 2 1 0 2 2 2 0 PQQ-like domain UpxZ PF06603.6 ETO31609.1 - 0.039 13.9 0.2 7.1 6.7 0.0 2.6 2 0 0 2 2 2 0 UpxZ family of transcription anti-terminator antagonists WD40 PF00400.27 ETO31610.1 - 8.1e-49 161.8 27.5 2.3e-09 36.7 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO31610.1 - 9.9e-11 40.4 7.9 0.041 12.0 0.1 5.0 2 1 2 5 5 5 5 Nucleoporin Nup120/160 MS_channel PF00924.13 ETO31611.1 - 0.028 13.7 0.4 0.046 13.0 0.3 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel Radial_spoke_3 PF06098.6 ETO31611.1 - 0.29 10.1 3.3 1.2 8.0 0.2 2.1 2 0 0 2 2 2 0 Radial spoke protein 3 ApoC-I PF04691.7 ETO31611.1 - 0.6 9.8 3.7 2.6 7.7 0.1 2.6 3 0 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) La PF05383.12 ETO31612.1 - 1.3e-17 63.3 0.0 3.6e-17 61.8 0.0 1.8 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 ETO31612.1 - 4.1e-07 29.5 0.0 0.0039 16.7 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO31612.1 - 9.3e-05 22.3 0.0 0.014 15.3 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO31612.1 - 0.091 12.6 0.3 11 6.0 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Complex1_LYR PF05347.10 ETO31613.1 - 0.37 10.6 1.9 1.3 8.9 1.3 1.9 1 0 0 1 1 1 0 Complex 1 protein (LYR family) DOMON PF03351.12 ETO31614.1 - 1.5e-05 24.8 0.3 2.6e-05 24.1 0.2 1.4 1 0 0 1 1 1 1 DOMON domain DUF2976 PF11190.3 ETO31614.1 - 0.031 13.8 0.2 0.067 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) Ion_trans PF00520.26 ETO31616.1 - 2.3e-15 56.4 0.5 7.3e-15 54.7 0.0 2.0 2 1 0 2 2 2 1 Ion transport protein DUF1542 PF07564.6 ETO31616.1 - 0.13 12.2 3.7 0.31 11.0 2.6 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) Pkinase PF00069.20 ETO31617.1 - 8.5e-09 34.9 0.1 9.6e-09 34.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO31617.1 - 0.00044 19.3 0.0 0.00054 19.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 ETO31618.1 - 9.8e-46 155.9 0.1 2.8e-45 154.5 0.1 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO31618.1 - 2.1e-30 105.6 0.1 4.1e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO31618.1 - 7.5e-05 21.8 0.0 0.00014 20.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETO31618.1 - 0.14 11.8 0.1 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Halogen_Hydrol PF10112.4 ETO31619.1 - 0.068 12.5 1.6 0.2 11.0 0.9 1.9 1 1 1 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein TMEMspv1-c74-12 PF11044.3 ETO31619.1 - 0.07 12.6 1.5 0.18 11.4 1.0 1.7 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Adeno_E3_CR2 PF02439.10 ETO31619.1 - 0.14 11.7 0.2 0.24 10.9 0.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Rab5ip PF07019.7 ETO31620.1 - 0.051 13.7 1.0 12 6.1 0.0 2.6 2 1 1 3 3 3 0 Rab5-interacting protein (Rab5ip) Ank_2 PF12796.2 ETO31621.1 - 1.2e-11 44.8 0.6 9.3e-05 22.6 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETO31621.1 - 1.6e-05 24.4 0.6 0.1 12.4 0.1 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 ETO31621.1 - 6.5e-05 22.7 0.9 0.98 9.8 0.0 4.6 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 ETO31621.1 - 0.00015 22.1 1.0 0.047 14.2 0.1 3.2 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO31621.1 - 0.011 15.9 0.8 0.085 13.1 0.0 2.9 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Pan_kinase PF03309.9 ETO31621.1 - 0.017 14.6 1.7 0.054 12.9 1.2 1.8 1 0 0 1 1 1 0 Type III pantothenate kinase PIP5K PF01504.13 ETO31622.1 - 5.6e-32 110.8 0.1 1e-31 109.9 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Tubulin PF00091.20 ETO31623.1 - 2.4e-35 122.3 0.0 3.9e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO31623.1 - 8.7e-33 113.0 0.0 1.4e-32 112.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Cpn60_TCP1 PF00118.19 ETO31624.1 - 1.2e-117 393.5 6.0 1.4e-102 343.8 2.5 2.0 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family LacAB_rpiB PF02502.13 ETO31624.1 - 0.0055 16.3 0.2 0.018 14.7 0.1 1.8 1 0 0 1 1 1 1 Ribose/Galactose Isomerase WD40 PF00400.27 ETO31625.1 - 4e-09 36.0 0.5 2.1e-07 30.5 0.1 2.9 3 0 0 3 3 3 1 WD domain, G-beta repeat Kelch_4 PF13418.1 ETO31626.1 - 5.1e-07 29.3 0.5 7.9e-05 22.3 0.1 2.5 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO31626.1 - 2.2e-05 23.9 2.4 7.9e-05 22.1 1.6 2.0 1 0 0 1 1 1 1 Kelch motif Kelch_2 PF07646.10 ETO31626.1 - 0.0038 16.9 2.3 0.015 15.0 0.4 2.6 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 ETO31626.1 - 0.0072 16.4 0.4 0.047 13.8 0.1 2.5 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO31626.1 - 0.0073 16.2 2.6 0.067 13.1 0.4 2.8 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 ETO31626.1 - 1.5 9.0 5.0 2.5 8.4 0.8 2.9 2 1 1 3 3 3 0 Kelch motif Kelch_2 PF07646.10 ETO31627.1 - 0.0013 18.4 1.5 0.05 13.3 0.3 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 ETO31627.1 - 0.0031 17.4 2.4 0.52 10.3 0.1 4.1 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 ETO31627.1 - 0.0039 16.7 0.3 0.0039 16.7 0.2 2.5 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 ETO31627.1 - 0.1 12.7 0.1 4.3 7.6 0.1 3.2 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO31627.1 - 0.13 12.4 3.3 3.2 8.0 0.1 3.8 5 0 0 5 5 5 0 Kelch motif GnHR_trans PF12369.3 ETO31627.1 - 0.33 11.4 4.5 0.21 12.0 0.8 2.3 3 0 0 3 3 3 0 Gonadotropin hormone receptor transmembrane region Sas10_Utp3 PF04000.10 ETO31629.1 - 0.02 15.1 1.0 0.02 15.1 0.7 1.9 2 0 0 2 2 2 0 Sas10/Utp3/C1D family DUF2611 PF11022.3 ETO31629.1 - 0.032 14.3 0.1 0.084 12.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2611) DUF106 PF01956.11 ETO31629.1 - 0.11 12.0 3.3 0.2 11.2 2.3 1.5 1 0 0 1 1 1 0 Integral membrane protein DUF106 Ribosomal_S20p PF01649.13 ETO31629.1 - 0.83 10.0 5.3 0.21 11.9 0.7 2.2 2 0 0 2 2 2 0 Ribosomal protein S20 Laminin_II PF06009.7 ETO31629.1 - 4.5 7.0 8.0 5 6.8 0.4 2.7 3 0 0 3 3 3 0 Laminin Domain II RPEL PF02755.10 ETO31632.1 - 6.3e-06 25.3 0.2 0.17 11.2 0.2 3.4 3 0 0 3 3 3 2 RPEL repeat EF-hand_6 PF13405.1 ETO31632.1 - 0.061 13.2 0.1 0.19 11.7 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain DUF725 PF05267.7 ETO31632.1 - 0.5 10.2 7.6 1.8 8.5 0.3 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF725) DnaJ PF00226.26 ETO31633.1 - 1.4e-25 88.8 1.0 2.3e-25 88.1 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 ETO31633.1 - 4.2e-23 81.0 1.2 9.9e-23 79.8 0.3 2.0 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 ETO31633.1 - 8.9e-17 60.9 15.0 1.5e-16 60.1 10.4 1.4 1 0 0 1 1 1 1 DnaJ central domain PAAR_motif PF05488.8 ETO31633.1 - 0.012 15.5 4.8 2.2 8.3 0.1 2.4 2 0 0 2 2 2 0 PAAR motif CytoC_RC PF02276.13 ETO31633.1 - 0.053 12.6 0.0 0.08 12.0 0.0 1.2 1 0 0 1 1 1 0 Photosynthetic reaction centre cytochrome C subunit zf-C4_Topoisom PF01396.14 ETO31633.1 - 0.48 9.9 5.2 13 5.3 0.0 2.6 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger HypA PF01155.14 ETO31633.1 - 0.79 9.4 8.5 0.25 11.0 0.4 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 ETO31633.1 - 0.8 9.5 7.3 2.7 7.8 0.4 2.3 2 0 0 2 2 2 0 Double zinc ribbon PADR1 PF08063.7 ETO31633.1 - 1.4 8.3 9.3 1.6 8.1 1.8 2.5 3 0 0 3 3 3 0 PADR1 (NUC008) domain A2L_zn_ribbon PF08792.5 ETO31633.1 - 2.4 7.6 13.8 3 7.4 0.5 3.4 2 1 1 3 3 3 0 A2L zinc ribbon domain Lar_restr_allev PF14354.1 ETO31633.1 - 4.4 7.6 7.4 2.8 8.3 2.2 2.7 1 1 1 2 2 2 0 Restriction alleviation protein Lar zf-RING_3 PF14369.1 ETO31633.1 - 6.6 6.8 14.9 15 5.6 2.8 4.1 3 1 1 4 4 4 0 zinc-finger Pkinase PF00069.20 ETO31634.1 - 0.00016 20.9 0.0 0.00031 19.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain BUD22 PF09073.5 ETO31634.1 - 0.015 14.4 17.8 0.022 13.8 12.3 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.7 ETO31634.1 - 0.072 12.3 17.1 0.1 11.8 11.9 1.3 1 0 0 1 1 1 0 SDA1 Ribosomal_L7Ae PF01248.21 ETO31634.1 - 0.14 11.6 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CDC45 PF02724.9 ETO31634.1 - 0.17 9.8 11.9 0.23 9.4 8.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 ETO31634.1 - 0.23 9.0 4.6 0.29 8.7 3.2 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nop14 PF04147.7 ETO31634.1 - 0.51 8.1 27.5 0.84 7.4 19.1 1.3 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 ETO31634.1 - 8.6 4.7 20.0 14 4.0 13.8 1.3 1 0 0 1 1 1 0 Daxx Family Nop16 PF09420.5 ETO31635.1 - 3.3 7.7 8.8 0.56 10.2 2.1 2.3 2 0 0 2 2 2 0 Ribosome biogenesis protein Nop16 TPR_MLP1_2 PF07926.7 ETO31636.1 - 0.00014 21.6 7.9 0.00047 19.8 1.4 2.3 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 ETO31636.1 - 0.00084 18.3 1.7 0.00084 18.3 1.2 1.9 2 0 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 Cast PF10174.4 ETO31636.1 - 0.0018 16.4 3.3 0.0018 16.4 2.3 1.9 2 0 0 2 2 2 1 RIM-binding protein of the cytomatrix active zone COG2 PF06148.6 ETO31636.1 - 0.0021 17.9 0.8 0.099 12.5 0.1 2.2 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Bap31 PF05529.7 ETO31636.1 - 0.0035 16.8 4.9 0.022 14.2 1.0 2.3 2 0 0 2 2 2 1 B-cell receptor-associated protein 31-like CENP-F_leu_zip PF10473.4 ETO31636.1 - 0.0036 17.1 4.3 0.0036 17.1 3.0 2.2 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.6 ETO31636.1 - 0.0042 16.9 2.2 2.1 8.2 1.0 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FliJ PF02050.11 ETO31636.1 - 0.0046 17.0 1.7 0.0046 17.0 1.2 2.4 3 0 0 3 3 2 1 Flagellar FliJ protein ADIP PF11559.3 ETO31636.1 - 0.0092 15.8 2.5 0.0092 15.8 1.7 2.3 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding WEMBL PF05701.6 ETO31636.1 - 0.01 14.3 1.3 0.01 14.3 0.9 2.1 2 0 0 2 2 2 0 Weak chloroplast movement under blue light COG5 PF10392.4 ETO31636.1 - 0.014 15.3 2.3 0.058 13.3 0.2 2.2 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF869 PF05911.6 ETO31636.1 - 0.015 13.6 0.9 0.015 13.6 0.6 1.6 2 0 0 2 2 2 0 Plant protein of unknown function (DUF869) CENP-Q PF13094.1 ETO31636.1 - 0.016 15.2 4.7 0.016 15.2 3.3 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit CCDC-167 PF15188.1 ETO31636.1 - 0.017 15.0 1.0 0.017 15.0 0.7 2.8 2 1 1 3 3 2 0 Coiled-coil domain-containing protein 167 Mod_r PF07200.8 ETO31636.1 - 0.019 14.9 4.1 0.019 14.9 2.9 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Prefoldin_2 PF01920.15 ETO31636.1 - 0.021 14.5 6.8 0.021 14.5 4.7 2.4 2 0 0 2 2 2 0 Prefoldin subunit Bacillus_HBL PF05791.6 ETO31636.1 - 0.027 13.8 6.0 0.063 12.6 1.2 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) HSCB_C PF07743.8 ETO31636.1 - 0.034 14.6 4.1 0.84 10.1 0.2 2.3 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain Exonuc_VII_L PF02601.10 ETO31636.1 - 0.034 13.3 0.9 0.049 12.8 0.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit WXG100 PF06013.7 ETO31636.1 - 0.044 13.7 4.6 0.093 12.7 0.7 2.2 2 0 0 2 2 2 0 Proteins of 100 residues with WXG FlaC_arch PF05377.6 ETO31636.1 - 0.044 13.6 1.7 0.044 13.6 1.2 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.10 ETO31636.1 - 0.054 12.9 10.0 0.56 9.7 0.3 2.9 2 0 0 2 2 2 0 Septum formation initiator DUF1640 PF07798.6 ETO31636.1 - 0.056 13.4 4.5 0.47 10.4 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) P4Ha_N PF08336.6 ETO31636.1 - 0.067 13.0 5.6 0.12 12.1 0.5 2.3 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region PEP-utilisers_N PF05524.8 ETO31636.1 - 0.071 12.9 0.8 0.33 10.7 0.0 2.0 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Spc7 PF08317.6 ETO31636.1 - 0.077 11.6 8.6 0.029 13.0 1.3 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Sec8_exocyst PF04048.9 ETO31636.1 - 0.082 12.5 4.4 0.11 12.1 0.4 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain UPF0449 PF15136.1 ETO31636.1 - 0.1 12.8 8.1 1.9 8.7 0.6 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF4140 PF13600.1 ETO31636.1 - 0.1 13.0 5.8 0.37 11.2 0.6 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Gp58 PF07902.6 ETO31636.1 - 0.11 10.7 0.1 0.13 10.4 0.1 1.1 1 0 0 1 1 1 0 gp58-like protein CHD5 PF04420.9 ETO31636.1 - 0.15 11.7 2.3 9.2 5.9 1.0 2.7 2 1 0 2 2 2 0 CHD5-like protein TBPIP PF07106.8 ETO31636.1 - 0.17 11.4 9.4 0.071 12.6 1.6 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4279 PF14106.1 ETO31636.1 - 0.17 11.7 4.3 2.4 8.0 0.5 2.6 1 1 2 3 3 2 0 Domain of unknown function (DUF4279) Seryl_tRNA_N PF02403.17 ETO31636.1 - 0.18 11.8 6.6 0.64 10.0 0.3 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Kinetocho_Slk19 PF12709.2 ETO31636.1 - 0.18 11.8 12.8 0.14 12.2 2.8 2.5 2 0 0 2 2 2 0 Central kinetochore-associated V-SNARE PF05008.10 ETO31636.1 - 0.18 11.9 9.1 0.46 10.6 0.7 2.4 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Tropomyosin_1 PF12718.2 ETO31636.1 - 0.19 11.6 13.4 0.052 13.4 2.7 2.3 2 0 0 2 2 2 0 Tropomyosin like DUF4618 PF15397.1 ETO31636.1 - 0.19 11.0 7.1 0.28 10.4 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Spc24 PF08286.6 ETO31636.1 - 0.2 11.3 10.2 0.032 13.9 1.6 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 GrpE PF01025.14 ETO31636.1 - 0.21 11.0 8.3 0.23 10.9 2.0 2.1 2 0 0 2 2 2 0 GrpE Med4 PF10018.4 ETO31636.1 - 0.21 10.9 7.1 3.6 6.9 1.5 2.2 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Prefoldin PF02996.12 ETO31636.1 - 0.25 10.9 11.7 0.07 12.7 3.1 2.4 2 0 0 2 2 2 0 Prefoldin subunit DUF904 PF06005.7 ETO31636.1 - 0.27 11.5 17.2 0.99 9.7 2.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF4200 PF13863.1 ETO31636.1 - 0.32 10.9 13.7 0.4 10.6 2.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DegS PF05384.6 ETO31636.1 - 0.33 10.1 4.2 0.8 8.9 0.2 2.2 2 0 0 2 2 2 0 Sensor protein DegS HrpB7 PF09486.5 ETO31636.1 - 0.33 10.8 2.2 1 9.2 0.6 2.0 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF1049 PF06305.6 ETO31636.1 - 0.34 10.4 5.6 1.8 8.0 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1049) DUF607 PF04678.8 ETO31636.1 - 0.34 10.8 4.7 1.3 8.9 0.7 2.4 1 1 1 2 2 2 0 Protein of unknown function, DUF607 DUF1664 PF07889.7 ETO31636.1 - 0.38 10.5 2.5 0.87 9.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Lectin_N PF03954.9 ETO31636.1 - 0.45 9.9 4.0 0.18 11.2 0.7 1.7 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Cob_adeno_trans PF01923.13 ETO31636.1 - 0.47 10.2 3.4 2.2 8.0 2.3 2.0 1 1 0 1 1 1 0 Cobalamin adenosyltransferase MscS_porin PF12795.2 ETO31636.1 - 0.48 9.6 12.4 0.066 12.5 4.2 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Lge1 PF11488.3 ETO31636.1 - 0.5 10.5 5.3 7.3 6.8 1.9 2.4 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 Uso1_p115_C PF04871.8 ETO31636.1 - 0.53 10.2 7.5 2.2 8.1 0.9 2.3 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Fib_alpha PF08702.5 ETO31636.1 - 0.54 10.3 4.2 0.48 10.5 0.6 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Filament PF00038.16 ETO31636.1 - 0.58 9.5 10.9 1.6 8.1 7.6 1.6 1 1 0 1 1 1 0 Intermediate filament protein Snapin_Pallidin PF14712.1 ETO31636.1 - 0.62 10.4 8.3 0.11 12.7 1.9 2.2 2 0 0 2 2 2 0 Snapin/Pallidin Lebercilin PF15619.1 ETO31636.1 - 0.64 9.3 11.1 0.24 10.7 2.5 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF4201 PF13870.1 ETO31636.1 - 0.66 9.3 16.0 0.06 12.7 3.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) Phage_GP20 PF06810.6 ETO31636.1 - 0.85 9.0 13.0 0.076 12.4 2.3 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 FlxA PF14282.1 ETO31636.1 - 0.97 9.4 12.7 0.18 11.7 3.2 2.2 2 0 0 2 2 2 0 FlxA-like protein Med9 PF07544.8 ETO31636.1 - 0.98 9.1 5.8 0.58 9.9 0.8 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 RTBV_P46 PF06216.6 ETO31636.1 - 1.1 8.0 8.7 0.057 12.2 1.1 2.0 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein Laminin_II PF06009.7 ETO31636.1 - 1.1 9.0 5.9 0.34 10.6 1.3 1.9 2 0 0 2 2 2 0 Laminin Domain II CENP-F_N PF10481.4 ETO31636.1 - 1.9 7.7 9.5 0.19 11.0 1.3 2.0 2 0 0 2 2 2 0 Cenp-F N-terminal domain Tropomyosin PF00261.15 ETO31636.1 - 2 7.4 10.2 0.28 10.2 1.8 2.1 2 0 0 2 2 2 0 Tropomyosin DivIVA PF05103.8 ETO31636.1 - 2 8.4 9.9 0.5 10.4 2.1 2.2 2 0 0 2 2 2 0 DivIVA protein YajC PF02699.10 ETO31636.1 - 2.1 8.0 4.6 0.48 10.1 0.3 2.1 2 0 0 2 2 1 0 Preprotein translocase subunit Cep57_MT_bd PF06657.8 ETO31636.1 - 2.3 8.2 8.6 3.1 7.8 1.8 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF972 PF06156.8 ETO31636.1 - 2.7 8.3 8.1 1.6 9.1 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 ETO31636.1 - 2.9 7.4 18.9 0.12 11.9 5.4 2.2 1 1 0 2 2 2 0 IncA protein Nup88 PF10168.4 ETO31636.1 - 2.9 5.6 7.8 0.25 9.1 1.7 1.7 2 0 0 2 2 2 0 Nuclear pore component Syntaxin-6_N PF09177.6 ETO31636.1 - 3 8.3 5.7 4.1 7.8 0.9 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF641 PF04859.7 ETO31636.1 - 3.3 7.4 7.8 0.39 10.4 0.8 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF3763 PF12592.3 ETO31636.1 - 3.3 7.3 11.6 5.3 6.7 0.9 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF3763) TMF_TATA_bd PF12325.3 ETO31636.1 - 3.5 7.3 10.4 1.6 8.4 1.8 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Prp19 PF08606.6 ETO31636.1 - 3.8 7.3 8.6 0.29 10.9 2.0 1.9 2 0 0 2 2 1 0 Prp19/Pso4-like Tektin PF03148.9 ETO31636.1 - 4.5 5.6 9.9 1.9 6.9 3.0 2.0 2 0 0 2 2 2 0 Tektin family HR1 PF02185.11 ETO31636.1 - 4.7 7.0 12.3 0.36 10.6 2.0 2.6 2 0 0 2 2 2 0 Hr1 repeat OmpH PF03938.9 ETO31636.1 - 5.4 6.9 12.8 20 5.0 8.9 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) OEP PF02321.13 ETO31636.1 - 5.9 6.4 9.2 0.48 9.9 2.6 1.7 2 0 0 2 2 1 0 Outer membrane efflux protein BicD PF09730.4 ETO31636.1 - 6.9 4.8 11.6 0.19 10.0 3.0 1.8 2 0 0 2 2 2 0 Microtubule-associated protein Bicaudal-D Nup54 PF13874.1 ETO31636.1 - 7.3 6.2 13.0 2.6 7.7 2.9 2.1 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 ERM PF00769.14 ETO31636.1 - 8.3 5.8 15.8 7.1e+02 -0.5 11.0 2.1 1 1 0 1 1 1 0 Ezrin/radixin/moesin family HlyD PF00529.15 ETO31636.1 - 8.9 5.5 8.8 0.92 8.7 2.8 1.6 2 0 0 2 2 2 0 HlyD family secretion protein DUF3552 PF12072.3 ETO31636.1 - 9.7 5.3 12.5 3.5 6.7 2.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Adaptin_N PF01602.15 ETO31638.1 - 4.4e-113 378.3 13.1 6.8e-113 377.7 9.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 ETO31638.1 - 3.8e-13 49.5 0.1 0.00025 21.2 0.0 5.4 3 1 2 5 5 5 3 HEAT repeats Cnd1 PF12717.2 ETO31638.1 - 9.9e-13 48.3 0.1 9.9e-13 48.3 0.1 3.9 3 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.5 ETO31638.1 - 3.3e-10 39.8 4.3 1.4e-06 28.1 0.6 3.1 2 0 0 2 2 2 2 Beta2-adaptin appendage, C-terminal sub-domain HEAT PF02985.17 ETO31638.1 - 6.2e-07 28.9 2.7 0.37 10.9 0.0 6.1 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 ETO31638.1 - 0.0006 20.2 0.2 18 5.9 0.0 5.0 6 1 1 7 7 7 2 HEAT-like repeat DUF2435 PF10363.4 ETO31638.1 - 0.0017 18.2 2.5 0.36 10.7 0.0 4.0 2 2 3 5 5 5 1 Protein of unknown function (DUF2435) WD40 PF00400.27 ETO31639.1 - 2.4e-29 100.1 18.2 9.4e-12 44.3 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO31639.1 - 0.0035 15.6 2.5 0.79 7.9 0.1 2.9 2 1 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.3 ETO31639.1 - 0.015 13.4 8.5 0.31 9.1 0.1 3.3 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Hexokinase_2 PF03727.11 ETO31640.1 - 0.076 12.2 0.4 0.16 11.1 0.2 1.5 1 0 0 1 1 1 0 Hexokinase DUF2167 PF09935.4 ETO31640.1 - 0.62 8.8 2.5 0.53 9.0 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2167) Kinesin PF00225.18 ETO31642.1 - 3.2e-95 318.6 0.0 3.2e-95 318.6 0.0 2.7 3 0 0 3 3 3 1 Kinesin motor domain BRE1 PF08647.6 ETO31642.1 - 0.0018 18.1 6.3 0.0018 18.1 4.4 8.9 6 2 3 9 9 9 1 BRE1 E3 ubiquitin ligase DUF904 PF06005.7 ETO31642.1 - 0.016 15.4 1.0 0.016 15.4 0.7 11.7 5 2 7 12 12 12 0 Protein of unknown function (DUF904) Reo_sigmaC PF04582.7 ETO31642.1 - 0.16 11.1 41.0 0.066 12.3 0.5 5.5 1 1 5 6 6 6 0 Reovirus sigma C capsid protein Filament PF00038.16 ETO31642.1 - 0.94 8.8 114.8 0.15 11.4 3.0 5.2 2 1 3 5 5 5 0 Intermediate filament protein ERM PF00769.14 ETO31642.1 - 8.9 5.7 119.3 0.0063 16.0 5.7 6.6 1 1 5 6 6 6 0 Ezrin/radixin/moesin family Acyltransferase PF01553.16 ETO31643.1 - 0.06 12.7 0.1 3.9 6.9 0.1 2.2 2 0 0 2 2 2 0 Acyltransferase DUF445 PF04286.7 ETO31644.1 - 0.071 12.6 2.7 0.83 9.1 0.1 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF445) Aldedh PF00171.17 ETO31645.1 - 3.5e-25 88.2 0.0 1.8e-12 46.3 0.0 3.2 2 1 1 3 3 3 3 Aldehyde dehydrogenase family NRN1 PF15056.1 ETO31645.1 - 0.15 12.0 0.2 0.15 12.0 0.1 2.2 2 0 0 2 2 2 0 Neuritin protein family Desulfoferrod_N PF06397.7 ETO31646.1 - 0.12 11.8 1.0 0.25 10.7 0.7 1.5 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain WD40 PF00400.27 ETO31647.1 - 0.01 15.6 0.0 0.53 10.2 0.0 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat Guanylate_cyc PF00211.15 ETO31648.1 - 1.7e-12 47.0 0.0 2.6e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain FtsJ PF01728.14 ETO31650.1 - 0.043 13.7 0.0 0.045 13.7 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase PMM PF03332.8 ETO31650.1 - 0.073 12.6 0.5 0.096 12.2 0.4 1.3 1 1 0 1 1 1 0 Eukaryotic phosphomannomutase BNR_assoc_N PF14873.1 ETO31650.1 - 0.087 12.5 0.1 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of BNR-repeat neuraminidase PFO_beta_C PF12367.3 ETO31650.1 - 0.093 12.6 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal WD40 PF00400.27 ETO31651.1 - 6.5e-71 231.9 16.7 4.2e-12 45.4 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO31651.1 - 3.3e-11 43.2 0.1 1.2e-05 25.1 0.0 3.3 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO31651.1 - 1.4e-08 33.3 8.7 0.19 9.8 0.1 5.8 1 1 4 6 6 6 4 Nucleoporin Nup120/160 PD40 PF07676.7 ETO31651.1 - 1.7e-06 27.5 5.6 0.53 10.0 0.1 5.9 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO31651.1 - 2.1e-05 23.4 6.4 0.029 13.1 1.8 4.2 1 1 2 3 3 3 3 Nup133 N terminal like Surfac_D-trimer PF09006.6 ETO31651.1 - 0.0001 21.9 0.0 4.8 6.9 0.0 4.3 4 0 0 4 4 4 1 Lung surfactant protein D coiled-coil trimerisation Coatomer_WDAD PF04053.9 ETO31651.1 - 0.00012 20.9 1.3 0.63 8.7 0.1 2.9 1 1 2 3 3 3 2 Coatomer WD associated region DPPIV_N PF00930.16 ETO31651.1 - 0.00013 20.6 0.0 0.092 11.3 0.0 3.4 2 1 1 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Str_synth PF03088.11 ETO31651.1 - 0.00013 21.8 0.1 4.1 7.4 0.0 4.0 4 1 0 4 4 4 1 Strictosidine synthase PQQ_2 PF13360.1 ETO31651.1 - 0.00015 21.3 0.6 0.0092 15.4 0.1 2.7 1 1 2 3 3 3 1 PQQ-like domain Proteasome_A_N PF10584.4 ETO31651.1 - 0.00022 20.4 5.9 2.4 7.5 0.0 5.5 6 0 0 6 6 6 2 Proteasome subunit A N-terminal signature Resistin PF06954.6 ETO31651.1 - 0.001 19.3 2.4 16 5.8 0.0 4.2 2 2 1 4 4 4 0 Resistin Gmad1 PF10647.4 ETO31651.1 - 0.0015 17.9 0.0 0.053 12.9 0.0 2.7 2 1 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain DUF947 PF06102.7 ETO31651.1 - 0.034 13.9 0.0 0.052 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF947) Cytochrom_D1 PF02239.11 ETO31651.1 - 0.035 12.4 1.0 1 7.5 0.0 2.8 1 1 3 4 4 4 0 Cytochrome D1 heme domain IKI3 PF04762.7 ETO31651.1 - 0.15 9.8 0.9 2.5 5.7 0.0 2.5 1 1 2 3 3 3 0 IKI3 family Kelch_1 PF01344.20 ETO31652.1 - 1.3e-07 31.0 2.2 0.0034 16.8 0.3 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO31652.1 - 7.6e-06 25.8 0.4 0.82 9.9 0.0 4.3 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO31652.1 - 2.3e-05 23.9 1.7 1.3 8.9 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO31652.1 - 0.0002 21.2 0.0 11 6.1 0.0 4.8 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.1 ETO31652.1 - 0.00025 20.7 0.9 0.61 9.8 0.0 4.5 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO31652.1 - 0.0017 18.4 0.1 0.034 14.3 0.0 3.1 3 0 0 3 3 3 1 Galactose oxidase, central domain T2SJ PF11612.3 ETO31653.1 - 0.012 15.3 0.1 0.015 15.0 0.0 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein J OstA_C PF04453.9 ETO31653.1 - 0.033 13.2 4.8 0.042 12.9 3.3 1.1 1 0 0 1 1 1 0 Organic solvent tolerance protein Staphopain_pro PF14731.1 ETO31653.1 - 0.041 13.6 0.8 0.041 13.6 0.5 1.6 2 0 0 2 2 2 0 Staphopain proregion WD40 PF00400.27 ETO31654.1 - 1.3e-06 28.0 2.2 0.0011 18.7 0.0 4.3 5 0 0 5 5 5 1 WD domain, G-beta repeat Filament PF00038.16 ETO31654.1 - 0.0003 20.3 21.0 0.0003 20.3 14.6 6.2 4 2 3 7 7 7 1 Intermediate filament protein Seryl_tRNA_N PF02403.17 ETO31654.1 - 0.0049 16.8 17.6 0.0049 16.8 12.2 9.0 5 2 7 12 12 12 1 Seryl-tRNA synthetase N-terminal domain DUF2353 PF09789.4 ETO31654.1 - 1 8.5 94.5 0.53 9.4 23.0 5.8 4 1 2 6 6 6 0 Uncharacterized coiled-coil protein (DUF2353) Cloacin_immun PF03513.9 ETO31655.1 - 0.032 14.2 0.0 0.067 13.2 0.0 1.4 1 0 0 1 1 1 0 Cloacin immunity protein AAA_5 PF07728.9 ETO31657.1 - 2.5e-10 40.1 0.0 7.9e-08 32.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA PF00004.24 ETO31657.1 - 3e-08 33.9 0.0 1.6e-05 25.1 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 ETO31657.1 - 0.00014 22.1 0.1 0.00056 20.2 0.0 2.1 2 0 0 2 2 1 1 ABC transporter AAA_22 PF13401.1 ETO31657.1 - 0.00014 21.9 0.0 0.0084 16.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETO31657.1 - 0.00029 20.8 0.0 0.0021 18.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 ETO31657.1 - 0.00045 19.4 0.0 0.001 18.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 ETO31657.1 - 0.00048 20.0 0.1 0.0023 17.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 ETO31657.1 - 0.001 18.6 0.0 0.0027 17.2 0.0 1.7 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.4 ETO31657.1 - 0.0015 17.9 0.1 0.011 15.2 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Mg_chelatase PF01078.16 ETO31657.1 - 0.0021 17.2 0.1 1.9 7.6 0.0 3.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 ETO31657.1 - 0.0033 16.4 0.0 0.0075 15.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.9 ETO31657.1 - 0.0058 16.5 0.0 0.017 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 ETO31657.1 - 0.0071 16.4 0.0 0.12 12.3 0.0 2.7 3 0 0 3 3 2 1 Sigma-54 interaction domain Arch_ATPase PF01637.13 ETO31657.1 - 0.0091 15.7 0.0 0.0091 15.7 0.0 2.4 3 0 0 3 3 2 1 Archaeal ATPase Miro PF08477.8 ETO31657.1 - 0.01 16.3 0.3 0.068 13.6 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein RNA_helicase PF00910.17 ETO31657.1 - 0.014 15.5 0.2 0.71 10.0 0.1 3.4 3 1 0 3 3 3 0 RNA helicase AAA_18 PF13238.1 ETO31657.1 - 0.015 15.5 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 2 0 AAA domain Sigma54_activat PF00158.21 ETO31657.1 - 0.022 14.2 0.0 0.54 9.7 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_7 PF12775.2 ETO31657.1 - 0.028 13.4 0.0 17 4.3 0.0 3.1 3 0 0 3 3 3 0 P-loop containing dynein motor region D3 Peptidase_C69 PF03577.10 ETO31657.1 - 0.029 13.2 0.1 0.045 12.6 0.1 1.3 1 0 0 1 1 1 0 Peptidase family C69 NACHT PF05729.7 ETO31657.1 - 0.036 13.7 0.1 0.3 10.7 0.0 2.5 3 0 0 3 3 3 0 NACHT domain AAA_3 PF07726.6 ETO31657.1 - 0.042 13.4 0.0 5.6 6.5 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 ETO31657.1 - 0.043 14.6 2.5 0.11 13.2 0.2 2.9 2 1 0 2 2 2 0 AAA domain T2SE PF00437.15 ETO31657.1 - 0.046 12.6 0.2 0.15 10.9 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein IstB_IS21 PF01695.12 ETO31657.1 - 0.049 13.0 0.0 0.48 9.8 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein MCM PF00493.18 ETO31657.1 - 0.052 12.3 1.1 1.7 7.3 0.0 3.1 4 0 0 4 4 4 0 MCM2/3/5 family UPF0079 PF02367.12 ETO31657.1 - 0.091 12.3 0.6 0.29 10.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 ETO31657.1 - 0.23 11.7 0.2 0.23 11.7 0.1 3.1 2 2 1 3 3 2 0 AAA domain AAA_24 PF13479.1 ETO31657.1 - 0.25 10.9 0.0 0.25 10.9 0.0 2.6 3 1 1 4 4 4 0 AAA domain RNA_pol_Rpc4 PF05132.9 ETO31660.1 - 0.21 11.5 1.3 0.39 10.6 0.9 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Menin PF05053.8 ETO31660.1 - 0.29 9.2 4.1 0.28 9.3 2.9 1.1 1 0 0 1 1 1 0 Menin PPP4R2 PF09184.6 ETO31660.1 - 0.54 9.7 11.4 0.69 9.4 7.9 1.1 1 0 0 1 1 1 0 PPP4R2 Apc15p PF05841.6 ETO31660.1 - 3.6 8.3 13.1 6 7.6 9.1 1.3 1 0 0 1 1 1 0 Apc15p protein DUF4131 PF13567.1 ETO31661.1 - 0.034 13.5 0.3 0.034 13.5 0.2 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) VWA PF00092.23 ETO31662.1 - 0.04 13.6 0.0 0.058 13.1 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain Gly-zipper_Omp PF13488.1 ETO31663.1 - 3.2e-24 84.2 42.0 5.9e-05 22.6 0.3 7.2 1 1 3 4 4 4 4 Glycine zipper Gly-zipper_YMGG PF13441.1 ETO31663.1 - 8.5e-15 54.0 27.3 0.039 13.4 3.7 7.1 1 1 3 4 4 4 4 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.1 ETO31663.1 - 1.9e-06 27.4 37.0 0.38 10.4 0.6 5.9 1 1 2 3 3 3 2 Glycine-zipper containing OmpA-like membrane domain DUF456 PF04306.8 ETO31663.1 - 1.6e-05 24.9 104.4 1.5e+04 -7.0 21.6 7.4 1 1 1 2 2 2 0 Protein of unknown function (DUF456) Rick_17kDa_Anti PF05433.10 ETO31663.1 - 1.6e-05 24.4 72.6 0.038 13.6 5.3 9.9 2 2 3 5 5 5 2 Glycine zipper 2TM domain TraT PF05818.7 ETO31663.1 - 0.0054 16.1 27.0 40 3.5 5.0 5.3 1 1 1 2 2 2 0 Enterobacterial TraT complement resistance protein Bacteriocin_IIc PF10439.4 ETO31663.1 - 0.29 11.2 100.5 16 5.7 9.6 8.2 1 1 2 3 3 3 0 Bacteriocin class II with double-glycine leader peptide TM_helix PF05552.7 ETO31663.1 - 3.9 7.2 41.3 18 5.1 0.3 8.8 1 1 5 6 6 6 0 Conserved TM helix Plexin_cytopl PF08337.7 ETO31664.1 - 0.063 11.5 0.5 0.074 11.3 0.4 1.0 1 0 0 1 1 1 0 Plexin cytoplasmic RasGAP domain Pex16 PF08610.5 ETO31664.1 - 0.79 8.6 2.7 0.99 8.3 1.9 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF4581 PF15167.1 ETO31665.1 - 0.09 12.6 0.0 0.16 11.8 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4581) Malic_M PF03949.10 ETO31666.1 - 7.3e-43 146.9 0.0 8.7e-43 146.7 0.0 1.0 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain HTH_21 PF13276.1 ETO31667.1 - 0.23 11.5 1.6 0.27 11.2 0.1 1.9 2 0 0 2 2 2 0 HTH-like domain FNIP_N PF14636.1 ETO31667.1 - 0.6 10.5 12.0 1 9.8 8.3 1.3 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus Hid1 PF12722.2 ETO31667.1 - 1.1 6.9 13.4 1 6.9 9.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Tau95 PF09734.4 ETO31667.1 - 2.8 7.1 9.6 3.4 6.8 6.6 1.1 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit DUF913 PF06025.7 ETO31667.1 - 3.2 6.3 7.9 3.6 6.2 5.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FAM60A PF15396.1 ETO31667.1 - 4.2 7.0 9.3 4.3 7.0 6.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A AAA_18 PF13238.1 ETO31667.1 - 4.5 7.5 9.4 1.1 9.5 4.1 1.7 1 1 1 2 2 2 0 AAA domain GAGA_bind PF06217.7 ETO31667.1 - 5.1 6.9 11.9 5.3 6.9 8.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family eIF3_subunit PF08597.5 ETO31667.1 - 5.7 6.4 19.4 6 6.3 13.4 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DHHW PF14286.1 ETO31667.1 - 6.9 5.8 10.3 7.1 5.8 7.1 1.1 1 0 0 1 1 1 0 DHHW protein Mem_trans PF03547.13 ETO31667.1 - 7.1 4.8 6.6 7.7 4.6 4.6 1.1 1 0 0 1 1 1 0 Membrane transport protein WD40 PF00400.27 ETO31669.1 - 2.6e-59 195.0 16.7 2.6e-12 46.0 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat PQQ_2 PF13360.1 ETO31669.1 - 0.0016 17.9 0.0 0.059 12.8 0.0 2.3 1 1 0 2 2 2 1 PQQ-like domain PD40 PF07676.7 ETO31669.1 - 0.0019 17.8 4.8 1.2 8.9 0.0 4.4 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO31669.1 - 0.79 10.0 7.5 5.6 7.3 0.1 4.6 3 2 3 6 6 6 0 Resistin Kinesin PF00225.18 ETO31672.1 - 1.8e-57 194.5 0.1 1.8e-57 194.5 0.1 1.9 2 0 0 2 2 2 1 Kinesin motor domain DUF4600 PF15372.1 ETO31672.1 - 0.23 11.6 8.0 0.06 13.5 1.8 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4600) TSC22 PF01166.13 ETO31672.1 - 3.5 7.6 7.3 9.7 6.2 0.5 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family ADP_ribosyl_GH PF03747.9 ETO31673.1 - 3.7e-14 53.1 0.0 5.3e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase DUF927 PF06048.6 ETO31673.1 - 0.08 12.2 0.0 0.093 11.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF927) DUF2383 PF09537.5 ETO31673.1 - 0.089 13.0 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) Kinesin PF00225.18 ETO31674.1 - 5.6e-10 38.4 0.1 7.6e-10 37.9 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain SmpA_OmlA PF04355.8 ETO31674.1 - 0.0093 15.5 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 SmpA / OmlA family SAP18 PF06487.7 ETO31675.1 - 7.1e-26 90.3 0.0 9e-26 90.0 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Ephrin PF00812.12 ETO31675.1 - 0.0032 16.9 0.1 0.0047 16.4 0.0 1.2 1 0 0 1 1 1 1 Ephrin SFTA2 PF15210.1 ETO31676.1 - 0.32 10.6 3.0 0.69 9.5 0.6 2.2 2 0 0 2 2 2 0 Surfactant-associated protein 2 DUF4110 PF13422.1 ETO31677.1 - 0.081 12.7 0.2 0.11 12.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) TRI12 PF06609.8 ETO31678.1 - 8.3e-05 20.9 1.6 8.3e-05 20.9 1.1 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 ETO31678.1 - 0.00021 20.1 14.5 0.00021 20.1 10.0 2.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4496 PF14908.1 ETO31679.1 - 0.15 11.9 0.8 0.22 11.3 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4496) Mem_trans PF03547.13 ETO31680.1 - 2.5 6.3 9.5 0.43 8.8 2.2 2.1 2 0 0 2 2 2 0 Membrane transport protein Paramyxo_ncap PF00973.14 ETO31681.1 - 0.61 8.7 3.2 0.69 8.5 2.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein ResIII PF04851.10 ETO31681.1 - 0.75 9.5 4.0 1 9.1 2.7 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Patatin PF01734.17 ETO31682.1 - 3.2e-07 30.4 0.0 6.9e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase DUF3336 PF11815.3 ETO31683.1 - 1e-28 99.6 0.0 2.5e-28 98.4 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3336) Secretin_N_2 PF07655.8 ETO31683.1 - 4.1 7.8 13.1 7.2 7.0 9.1 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain APG12 PF04110.8 ETO31684.1 - 2.9e-21 75.4 1.6 7.2e-19 67.7 1.1 2.5 1 1 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Ank_2 PF12796.2 ETO31685.1 - 4.1e-38 129.6 3.1 8.1e-17 61.3 0.2 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETO31685.1 - 1.2e-33 113.2 0.2 3.3e-09 36.0 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.1 ETO31685.1 - 6.7e-27 90.8 1.4 5.1e-07 29.3 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 ETO31685.1 - 4.2e-25 87.2 1.5 7.7e-11 41.8 0.0 5.1 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO31685.1 - 1.2e-22 79.8 0.2 1e-06 29.0 0.0 4.3 3 1 1 4 4 4 4 Ankyrin repeats (many copies) DUF500 PF04366.7 ETO31686.1 - 3.2e-21 75.0 0.7 3.8e-15 55.4 0.9 2.4 2 0 0 2 2 2 2 Family of unknown function (DUF500) WD40 PF00400.27 ETO31688.1 - 1.2e-77 253.2 15.4 1.2e-11 44.0 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO31688.1 - 7.3e-11 40.9 7.2 0.036 12.1 0.0 5.1 1 1 4 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO31688.1 - 4.1e-06 25.7 19.7 0.25 10.0 1.4 5.4 1 1 4 5 5 5 4 Nup133 N terminal like Hira PF07569.6 ETO31688.1 - 2e-05 23.9 4.1 8.8 5.4 0.0 5.0 2 1 3 5 5 5 3 TUP1-like enhancer of split PQQ_2 PF13360.1 ETO31688.1 - 0.00016 21.2 0.0 0.2 11.0 0.0 3.3 1 1 1 2 2 2 2 PQQ-like domain Cytochrom_D1 PF02239.11 ETO31688.1 - 0.00025 19.4 0.8 0.059 11.6 0.0 2.8 1 1 3 4 4 4 2 Cytochrome D1 heme domain DUF3601 PF12208.3 ETO31688.1 - 0.012 15.5 4.4 2.7 7.9 0.0 4.9 3 2 3 6 6 6 0 Domain of unknown function (DUF3601) PDDEXK_1 PF12705.2 ETO31688.1 - 0.14 11.4 3.0 12 5.1 0.1 3.0 2 1 1 3 3 3 0 PD-(D/E)XK nuclease superfamily WD40 PF00400.27 ETO31689.1 - 5.6e-66 216.2 23.9 7.8e-12 44.5 0.4 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO31689.1 - 5.3e-09 34.7 9.0 3.7e-05 22.0 0.0 4.8 1 1 2 3 3 3 3 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO31689.1 - 5.6e-09 36.2 2.6 3.4e-08 33.7 1.8 2.5 1 0 0 1 1 1 1 TRAF-type zinc finger DUF3601 PF12208.3 ETO31689.1 - 1.3 9.0 5.9 2.3 8.2 0.0 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF3601) GerA PF03323.8 ETO31689.1 - 5.4 5.0 5.3 7.2 4.6 3.6 1.2 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein Rubis-subs-bind PF09273.6 ETO31691.1 - 0.064 13.1 0.1 0.54 10.1 0.0 2.1 1 1 0 2 2 2 0 Rubisco LSMT substrate-binding Ank_4 PF13637.1 ETO31692.1 - 0.00044 20.6 0.0 0.4 11.2 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO31692.1 - 0.011 16.0 0.0 4.4 7.6 0.1 2.3 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO31692.1 - 0.019 15.2 0.0 1.2 9.4 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.25 ETO31692.1 - 0.028 14.2 0.0 3.8 7.4 0.0 3.2 2 1 0 2 2 2 0 Ankyrin repeat Dicty_REP PF05086.7 ETO31692.1 - 4.2 5.0 8.4 5.8 4.5 5.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein N_Asn_amidohyd PF14736.1 ETO31693.1 - 0.0095 14.8 0.1 0.015 14.1 0.0 1.3 1 1 0 1 1 1 1 Protein N-terminal asparagine amidohydrolase Kelch_1 PF01344.20 ETO31693.1 - 0.033 13.7 2.1 1.8 8.1 0.0 2.7 3 0 0 3 3 3 0 Kelch motif Kelch_6 PF13964.1 ETO31693.1 - 0.041 14.0 0.1 0.75 10.0 0.0 2.3 2 0 0 2 2 2 0 Kelch motif WD40 PF00400.27 ETO31694.1 - 1.2e-61 202.5 20.1 4.7e-10 38.9 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO31694.1 - 1.3e-09 36.7 6.1 0.0036 15.4 0.1 4.8 3 2 1 5 5 5 4 Nucleoporin Nup120/160 Daxx PF03344.10 ETO31696.1 - 0.81 8.0 51.6 1.2 7.4 35.8 1.2 1 0 0 1 1 1 0 Daxx Family Peptidase_M14 PF00246.19 ETO31697.1 - 4.7e-14 52.6 1.7 7.3e-14 52.0 1.2 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase SOXp PF12336.3 ETO31697.1 - 0.018 15.6 0.5 0.29 11.7 0.1 2.5 2 0 0 2 2 2 0 SOX transcription factor GalP_UDP_tr_C PF02744.12 ETO31698.1 - 0.028 13.9 0.1 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain Abhydrolase_6 PF12697.2 ETO31699.1 - 2.7e-13 50.3 0.0 3.9e-06 26.9 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETO31699.1 - 3.2e-05 23.6 0.1 0.022 14.2 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold zf-RanBP PF00641.13 ETO31699.1 - 0.0014 17.7 8.0 0.0035 16.4 5.5 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others PDEase_I PF00233.14 ETO31700.1 - 1e-26 94.1 0.1 1.3e-26 93.7 0.0 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Sad1_UNC PF07738.8 ETO31702.1 - 0.1 12.3 0.0 0.42 10.3 0.0 1.9 2 0 0 2 2 2 0 Sad1 / UNC-like C-terminal Pkinase PF00069.20 ETO31703.1 - 6.3e-67 225.4 0.1 1.3e-66 224.3 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO31703.1 - 5.4e-40 137.0 0.0 5.7e-39 133.7 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO31703.1 - 1.1e-07 31.1 0.0 0.00026 20.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 ETO31703.1 - 0.012 14.7 0.0 0.026 13.5 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAP2 PF01569.16 ETO31704.1 - 0.055 13.1 2.2 0.095 12.3 0.1 2.5 3 0 0 3 3 3 0 PAP2 superfamily PIP5K PF01504.13 ETO31705.1 - 1.6e-70 237.0 0.5 2.5e-70 236.4 0.3 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Transposase_28 PF04195.7 ETO31705.1 - 0.0054 16.0 1.1 0.046 13.0 0.1 2.2 2 0 0 2 2 2 1 Putative gypsy type transposon IFT43 PF15305.1 ETO31705.1 - 0.1 12.6 6.4 0.24 11.4 4.5 1.6 1 0 0 1 1 1 0 Intraflagellar transport protein 43 Copine PF07002.11 ETO31706.1 - 0.046 13.4 0.0 0.12 12.1 0.0 1.6 1 1 0 1 1 1 0 Copine DUF3741 PF12552.3 ETO31706.1 - 0.19 11.5 1.0 0.25 11.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3741) PTPlike_phytase PF14566.1 ETO31707.1 - 1.2e-08 35.1 0.5 1.3e-07 31.7 0.0 2.2 2 0 0 2 2 2 1 Inositol hexakisphosphate MetJ PF01340.15 ETO31709.1 - 0.02 14.6 0.6 0.044 13.5 0.1 1.8 2 0 0 2 2 2 0 Met Apo-repressor, MetJ DXP_synthase_N PF13292.1 ETO31709.1 - 0.17 10.7 1.3 0.2 10.5 0.3 1.6 1 1 1 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Protocadherin PF08374.6 ETO31710.1 - 0.14 11.7 1.4 0.17 11.5 0.9 1.1 1 0 0 1 1 1 0 Protocadherin TPR_11 PF13414.1 ETO31712.1 - 1.6e-18 66.0 8.2 3.1e-09 36.3 0.1 4.3 2 2 0 4 4 4 3 TPR repeat TPR_1 PF00515.23 ETO31712.1 - 1.2e-12 46.8 2.0 0.00091 18.7 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO31712.1 - 2e-12 46.2 5.9 0.068 13.3 0.0 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO31712.1 - 3.1e-11 42.2 7.5 3.4e-05 23.4 0.2 5.5 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO31712.1 - 8.4e-10 38.4 1.4 0.042 14.5 0.0 5.5 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO31712.1 - 1.4e-09 38.1 0.2 0.0056 16.9 0.0 3.9 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO31712.1 - 2.7e-09 37.4 0.1 0.00042 20.9 0.0 3.9 3 1 1 4 4 4 3 Tetratricopeptide repeat SAM_2 PF07647.12 ETO31712.1 - 2.5e-08 33.6 0.1 1.5e-05 24.7 0.0 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) TPR_12 PF13424.1 ETO31712.1 - 2.8e-08 33.5 12.0 0.00021 21.1 0.3 4.1 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO31712.1 - 3.3e-07 29.5 0.4 0.086 12.6 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO31712.1 - 9.5e-06 25.7 0.8 0.34 11.4 0.0 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETO31712.1 - 1.4e-05 24.7 2.3 0.0034 17.1 0.0 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO31712.1 - 2.5e-05 24.3 9.3 0.00047 20.2 0.4 3.7 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 SAM_1 PF00536.25 ETO31712.1 - 2.7e-05 24.2 0.1 0.045 13.9 0.0 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) Ras PF00071.17 ETO31713.1 - 7.1e-15 54.7 0.2 8.8e-15 54.4 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO31713.1 - 6.6e-05 23.3 0.0 0.00011 22.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein RabGAP-TBC PF00566.13 ETO31714.1 - 1e-05 25.1 1.6 1.5e-05 24.5 1.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain OTOS PF15182.1 ETO31714.1 - 0.0055 16.3 0.9 0.014 15.0 0.2 1.9 2 0 0 2 2 2 1 Otospiralin TMEM238 PF15125.1 ETO31714.1 - 0.5 10.3 2.0 1.3 8.9 0.6 2.3 3 1 0 3 3 3 0 TMEM238 protein family zf-CCCH PF00642.19 ETO31715.1 - 0.34 10.6 4.8 0.55 9.9 2.2 2.4 1 1 1 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pex14_N PF04695.8 ETO31716.1 - 3.2 7.8 7.9 19 5.2 4.6 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1298 PF06974.8 ETO31717.1 - 0.051 13.3 0.2 0.051 13.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1298) Abhydrolase_6 PF12697.2 ETO31719.1 - 6.7e-17 62.1 0.0 1.7e-16 60.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETO31719.1 - 8.6e-10 38.5 0.0 4.5e-09 36.2 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETO31719.1 - 7.5e-08 32.2 0.0 0.0039 16.7 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.13 ETO31719.1 - 0.0024 17.1 0.1 0.16 11.2 0.0 2.3 2 0 0 2 2 2 1 Dienelactone hydrolase family YHYH PF14240.1 ETO31719.1 - 0.014 15.0 0.1 0.034 13.8 0.1 1.6 1 0 0 1 1 1 0 YHYH protein UPF0227 PF05728.7 ETO31719.1 - 0.066 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) NACHT PF05729.7 ETO31721.1 - 0.014 15.1 0.0 0.033 13.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain PBP1_TM PF14812.1 ETO31721.1 - 0.56 10.5 4.8 0.13 12.5 0.9 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal EF-hand_1 PF00036.27 ETO31722.1 - 1.9e-14 51.7 1.3 1.1e-07 30.6 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 ETO31722.1 - 5.1e-12 45.7 0.1 2.4e-05 24.3 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO31722.1 - 9.9e-11 40.5 1.1 4e-05 23.1 0.1 2.9 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 ETO31722.1 - 1.1e-09 37.7 1.1 4.1e-05 23.1 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 ETO31722.1 - 1.4e-09 36.8 1.8 0.00029 20.0 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_10 PF14788.1 ETO31722.1 - 0.0018 17.9 0.8 0.18 11.5 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_4 PF12763.2 ETO31722.1 - 0.0074 15.9 0.8 0.23 11.2 0.0 2.8 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 ETO31722.1 - 0.93 9.5 11.6 2.9 7.9 0.0 3.4 3 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region BAF1_ABF1 PF04684.8 ETO31722.1 - 1 8.1 21.2 0.33 9.7 9.8 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor WD40 PF00400.27 ETO31723.1 - 8.8e-66 215.6 20.1 8.3e-13 47.6 0.2 7.4 8 0 0 8 8 8 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO31723.1 - 5e-10 39.4 2.4 0.00032 20.4 0.1 3.5 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO31723.1 - 2.3e-06 26.0 5.7 0.019 13.1 0.1 3.5 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO31723.1 - 3.9e-06 25.4 1.6 0.00024 19.5 0.1 2.9 1 1 2 3 3 3 1 Cytochrome D1 heme domain B_lectin PF01453.19 ETO31723.1 - 6.2e-05 22.8 4.3 0.62 9.9 0.2 3.8 1 1 3 4 4 4 3 D-mannose binding lectin PD40 PF07676.7 ETO31723.1 - 0.0053 16.4 7.9 5.1 6.8 0.0 6.1 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO31723.1 - 0.032 13.6 0.3 4.6 6.6 0.0 2.3 2 0 0 2 2 2 0 PQQ-like domain DUF4221 PF13970.1 ETO31723.1 - 0.07 12.4 0.4 12 5.0 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4221) Proteasome_A_N PF10584.4 ETO31723.1 - 0.25 10.6 6.3 24 4.3 0.0 4.4 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature TRM PF02005.11 ETO31724.1 - 3.2e-16 59.2 0.0 1e-14 54.2 0.0 2.1 1 1 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase zf-CCCH PF00642.19 ETO31724.1 - 0.00011 21.7 7.1 0.00021 20.8 4.9 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF506 PF04720.7 ETO31724.1 - 0.14 11.7 4.3 0.17 11.4 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF506) Transposase_31 PF04754.7 ETO31726.1 - 3.6e-48 163.6 0.2 4.8e-48 163.2 0.1 1.1 1 0 0 1 1 1 1 Putative transposase, YhgA-like DDE_Tnp_1_3 PF13612.1 ETO31726.1 - 3e-25 88.7 0.0 5e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.16 ETO31726.1 - 0.014 14.9 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain DDE_Tnp_IS1595 PF12762.2 ETO31727.1 - 9e-27 93.7 0.7 2.1e-26 92.5 0.5 1.6 1 1 0 1 1 1 1 ISXO2-like transposase domain Zn_Tnp_IS1595 PF12760.2 ETO31727.1 - 3.4e-06 26.7 9.1 8.1e-06 25.5 6.3 1.7 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Sigma70_r4_2 PF08281.7 ETO31727.1 - 0.0047 16.3 0.0 0.0085 15.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.1 ETO31727.1 - 0.17 11.0 0.1 0.43 9.8 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 zf-H2C2_2 PF13465.1 ETO31727.1 - 0.6 10.4 4.7 0.29 11.5 0.4 2.3 2 0 0 2 2 2 0 Zinc-finger double domain Zn_Tnp_IS1 PF03811.8 ETO31727.1 - 1.4 8.4 4.2 2.6 7.5 2.9 1.5 1 0 0 1 1 1 0 InsA N-terminal domain A2L_zn_ribbon PF08792.5 ETO31727.1 - 2.1 7.9 7.1 4 7.0 4.9 1.5 1 0 0 1 1 1 0 A2L zinc ribbon domain TPR_11 PF13414.1 ETO31728.1 - 2e-07 30.5 1.1 3.5e-07 29.7 0.8 1.4 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 ETO31728.1 - 0.00077 19.1 0.4 0.093 12.6 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO31728.1 - 0.0037 17.9 0.2 0.0072 16.9 0.0 1.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO31728.1 - 0.0097 16.4 0.0 7.3 7.5 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO31728.1 - 0.038 13.6 1.0 0.29 10.8 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 ETO31728.1 - 0.048 13.8 0.0 0.15 12.3 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETO31728.1 - 0.11 12.8 0.2 0.25 11.6 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat SecA_DEAD PF07517.9 ETO31729.1 - 5.2e-39 134.1 0.0 1.3e-38 132.8 0.0 1.7 1 0 0 1 1 1 1 SecA DEAD-like domain LysM PF01476.15 ETO31729.1 - 4.8e-27 93.5 4.2 1.2e-11 44.3 0.0 4.5 4 0 0 4 4 4 2 LysM domain MASE1 PF05231.9 ETO31729.1 - 3.9 6.4 2.7 7.3 5.5 1.9 1.3 1 0 0 1 1 1 0 MASE1 EF-hand_4 PF12763.2 ETO31730.1 - 0.087 12.5 4.0 3.4 7.4 0.6 2.5 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Abi_2 PF07751.6 ETO31730.1 - 6.2 6.9 16.0 0.05 13.7 2.1 2.7 1 1 1 2 2 2 0 Abi-like protein WD40 PF00400.27 ETO31733.1 - 2.7e-62 204.5 6.4 1.1e-11 44.0 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat PD40 PF07676.7 ETO31733.1 - 2.9e-08 33.1 3.4 0.022 14.4 0.0 4.9 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO31733.1 - 6.1e-07 27.9 4.5 0.0068 14.5 0.0 4.0 1 1 3 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO31733.1 - 5.9e-06 26.1 0.0 0.00018 21.2 0.0 2.6 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 ETO31733.1 - 0.011 14.7 0.4 2.4 7.1 0.0 3.4 2 1 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 ETO31733.1 - 0.021 13.1 0.1 15 3.7 0.0 3.0 1 1 2 3 3 3 0 Cytochrome D1 heme domain Gmad1 PF10647.4 ETO31733.1 - 0.081 12.3 0.0 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain Proteasome_A_N PF10584.4 ETO31733.1 - 2.6 7.4 14.6 23 4.4 0.1 5.7 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature B56 PF01603.15 ETO31734.1 - 2.1e-12 46.3 0.1 3.7e-12 45.5 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Thioredoxin_2 PF13098.1 ETO31735.1 - 0.0061 16.7 0.2 0.0069 16.5 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain AA_permease_N PF08403.5 ETO31735.1 - 0.077 12.3 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Amino acid permease N-terminal DUF3945 PF13101.1 ETO31735.1 - 0.14 11.4 0.3 0.32 10.3 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3945) DUF3449 PF11931.3 ETO31737.1 - 4e-54 183.1 1.6 4e-54 183.1 1.1 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) zf-C2H2_jaz PF12171.3 ETO31737.1 - 1.5e-05 24.9 3.3 0.00088 19.3 0.5 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 ETO31737.1 - 0.0041 17.2 0.1 0.56 10.5 0.2 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 ETO31737.1 - 0.026 14.8 3.5 1.1 9.6 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger SF3a60_bindingd PF12108.3 ETO31737.1 - 0.055 13.0 0.5 0.055 13.0 0.4 2.2 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain FancD2 PF14631.1 ETO31737.1 - 0.098 9.7 1.9 0.14 9.2 1.3 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease RNA_pol_Rpb1_3 PF04983.13 ETO31737.1 - 0.1 12.3 0.4 0.25 11.0 0.3 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 3 zf-C2H2_2 PF12756.2 ETO31737.1 - 0.58 10.3 8.8 1.6 8.9 0.1 3.4 4 0 0 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 ETO31737.1 - 0.76 10.2 5.8 9.6 6.7 0.9 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF2892 PF11127.3 ETO31738.1 - 0.045 13.5 1.7 0.045 13.5 1.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2892) ATC_hydrolase PF14196.1 ETO31739.1 - 0.011 16.1 1.7 0.24 11.8 1.2 2.4 1 1 0 1 1 1 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase Tsg PF04668.7 ETO31739.1 - 0.015 15.5 0.1 0.045 13.9 0.1 1.8 1 0 0 1 1 1 0 Twisted gastrulation (Tsg) protein conserved region GTPase_Cys_C PF12631.2 ETO31739.1 - 0.065 13.6 0.0 2 8.9 0.0 2.4 2 0 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Sec7 PF01369.15 ETO31740.1 - 2.2e-43 148.1 7.6 5.6e-43 146.8 5.3 1.7 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 ETO31740.1 - 7.9e-36 123.0 2.7 7.9e-36 123.0 1.9 2.9 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Sec62 PF03839.11 ETO31744.1 - 1 8.7 4.3 1.2 8.4 3.0 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Vfa1 PF08432.5 ETO31744.1 - 1.3 9.0 7.7 1.7 8.6 5.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Ank_2 PF12796.2 ETO31745.1 - 7.2e-09 35.8 0.7 1.9e-05 24.9 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO31745.1 - 7.8e-06 25.6 0.0 1.3 9.4 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.25 ETO31745.1 - 1.1e-05 24.9 0.0 0.54 10.1 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 ETO31745.1 - 0.00051 20.4 0.1 0.35 11.4 0.0 4.4 3 1 2 5 5 5 2 Ankyrin repeats (many copies) AAA PF00004.24 ETO31745.1 - 0.14 12.3 1.7 0.38 10.9 1.2 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Transposase_mut PF00872.13 ETO31746.1 - 0.34 9.4 3.4 0.72 8.3 1.5 2.3 2 1 1 3 3 3 0 Transposase, Mutator family DUF1371 PF07115.6 ETO31746.1 - 0.95 9.6 5.8 0.38 10.9 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1371) M11L PF11099.3 ETO31748.1 - 0.0092 15.7 0.8 0.018 14.7 0.5 1.5 1 0 0 1 1 1 1 Apoptosis regulator M11L like Lipoprotein_X PF03305.8 ETO31749.1 - 0.00067 19.1 9.2 0.00097 18.5 6.4 1.2 1 0 0 1 1 1 1 Mycoplasma MG185/MG260 protein DUF1419 PF07215.6 ETO31749.1 - 1.5 8.6 4.8 16 5.3 0.3 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1419) PRP4 PF08799.6 ETO31752.1 - 4.3e-13 48.2 0.4 4.3e-13 48.2 0.3 2.3 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like WD40 PF00400.27 ETO31752.1 - 0.0096 15.7 0.1 0.067 13.1 0.0 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat Sec34 PF04136.10 ETO31752.1 - 0.033 13.9 0.8 0.05 13.3 0.0 1.7 2 0 0 2 2 2 0 Sec34-like family DUF1319 PF07028.6 ETO31752.1 - 0.052 13.7 0.1 0.052 13.7 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) GAS PF13851.1 ETO31752.1 - 1.3 8.2 15.5 0.89 8.7 1.1 2.7 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3959 PF13105.1 ETO31752.1 - 1.6 7.9 9.1 0.28 10.4 2.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3959) UPF0240 PF06784.6 ETO31752.1 - 1.8 8.2 7.8 0.66 9.6 2.8 2.1 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0240) Spc42p PF11544.3 ETO31752.1 - 1.9 8.5 7.4 0.41 10.6 2.2 2.2 2 1 0 2 2 2 0 Spindle pole body component Spc42p TUG-UBL1 PF11470.3 ETO31753.1 - 0.059 13.2 3.0 0.14 12.1 1.5 2.0 2 0 0 2 2 2 0 GLUT4 regulating protein TUG Ank_4 PF13637.1 ETO31754.1 - 4.5e-07 30.2 1.7 0.0092 16.4 0.0 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) XK-related PF09815.4 ETO31754.1 - 1.1e-05 24.6 16.3 1.1e-05 24.6 11.3 3.5 3 1 0 3 3 3 1 XK-related protein Ank_2 PF12796.2 ETO31754.1 - 2.2e-05 24.6 0.1 7.8e-05 22.9 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO31754.1 - 0.0015 18.6 0.5 0.14 12.4 0.0 3.4 2 1 1 3 3 3 1 Ankyrin repeats (many copies) CPSase_L_D3 PF02787.14 ETO31755.1 - 0.0022 17.7 1.5 0.0054 16.4 1.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain SUZ PF12752.2 ETO31755.1 - 3.9 8.0 9.5 2.3 8.8 0.7 2.7 2 0 0 2 2 2 0 SUZ domain K_trans PF02705.11 ETO31755.1 - 4.5 5.5 5.3 4.1 5.6 3.3 1.3 1 1 0 1 1 1 0 K+ potassium transporter Toprim_2 PF13155.1 ETO31755.1 - 6.4 7.1 6.8 1.2 9.5 1.7 2.0 2 1 0 2 2 2 0 Toprim-like Lactamase_B PF00753.22 ETO31756.1 - 1.2e-06 28.3 0.8 3.1e-06 26.9 0.5 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETO31756.1 - 0.00034 20.2 0.1 0.00039 20.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain CENP-F_leu_zip PF10473.4 ETO31757.1 - 0.012 15.4 13.6 0.016 15.0 9.4 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TBPIP PF07106.8 ETO31757.1 - 0.029 13.9 14.6 0.27 10.7 2.9 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc24 PF08286.6 ETO31757.1 - 0.036 13.7 9.4 0.6 9.8 1.1 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Abp2 PF09441.5 ETO31757.1 - 0.037 13.9 0.8 0.047 13.6 0.6 1.3 1 0 0 1 1 1 0 ARS binding protein 2 TMF_TATA_bd PF12325.3 ETO31757.1 - 0.063 13.0 10.4 0.21 11.3 2.0 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CENP-Q PF13094.1 ETO31757.1 - 0.082 12.9 11.1 0.11 12.5 7.7 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Baculo_PEP_C PF04513.7 ETO31757.1 - 0.1 12.3 0.3 0.3 10.9 0.1 1.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2570 PF10828.3 ETO31757.1 - 0.14 11.7 4.0 0.05 13.1 0.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) Peptidase_M16 PF00675.15 ETO31757.1 - 0.18 11.5 3.4 0.46 10.2 0.7 2.2 1 1 1 2 2 2 0 Insulinase (Peptidase family M16) MIF4G_like_2 PF09090.6 ETO31757.1 - 0.2 10.8 6.4 0.26 10.5 4.4 1.1 1 0 0 1 1 1 0 MIF4G like Fungal_trans_2 PF11951.3 ETO31757.1 - 0.23 10.0 4.3 0.15 10.6 0.7 1.8 1 1 0 2 2 2 0 Fungal specific transcription factor domain NAP PF00956.13 ETO31757.1 - 0.29 10.2 8.6 0.43 9.6 1.6 2.2 1 1 1 2 2 2 0 Nucleosome assembly protein (NAP) DUF3417 PF11897.3 ETO31757.1 - 0.43 10.5 3.1 0.31 11.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3417) APG6 PF04111.7 ETO31757.1 - 0.96 8.4 16.0 1.4 7.9 3.5 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 FlaC_arch PF05377.6 ETO31757.1 - 1.4 8.8 5.6 13 5.7 0.1 2.7 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF972 PF06156.8 ETO31757.1 - 1.8 8.9 9.8 6 7.2 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 ETO31757.1 - 1.8 8.0 14.4 3.6 7.1 6.5 1.8 1 1 0 1 1 1 0 IncA protein DUF4337 PF14235.1 ETO31757.1 - 1.9 8.3 11.6 4.1 7.2 1.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) TPR_MLP1_2 PF07926.7 ETO31757.1 - 2.2 8.0 13.3 2.4 7.9 1.6 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein EMP24_GP25L PF01105.19 ETO31757.1 - 2.4 7.8 6.2 3.7 7.2 4.3 1.3 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD MADF_DNA_bdg PF10545.4 ETO31757.1 - 2.7 8.2 7.2 28 4.9 5.0 2.4 1 1 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like UPF0242 PF06785.6 ETO31757.1 - 3 6.4 8.8 0.16 10.6 1.9 1.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) DUF1910 PF08928.5 ETO31757.1 - 5.4 7.0 7.7 8.2 6.4 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) Nsp1_C PF05064.8 ETO31757.1 - 5.5 6.6 10.8 31 4.2 3.3 2.9 1 1 1 2 2 2 0 Nsp1-like C-terminal region V_ATPase_I PF01496.14 ETO31757.1 - 6.8 4.4 8.9 7.6 4.2 6.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.1 ETO31757.1 - 8.5 5.2 7.5 11 4.8 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-HC5HC2H PF13771.1 ETO31758.1 - 1.2e-06 28.5 3.4 1.2e-06 28.5 2.4 2.4 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 ETO31758.1 - 2.7e-05 24.0 4.7 2.7e-05 24.0 3.3 2.6 2 0 0 2 2 2 1 PHD-zinc-finger like domain Daxx PF03344.10 ETO31758.1 - 0.0086 14.6 46.5 0.012 14.0 32.3 1.1 1 0 0 1 1 1 1 Daxx Family WD40 PF00400.27 ETO31759.1 - 0.0019 18.0 9.4 0.39 10.6 0.4 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Clathrin_propel PF01394.15 ETO31759.1 - 0.84 10.0 3.8 36 4.9 0.0 3.9 5 0 0 5 5 5 0 Clathrin propeller repeat KH_1 PF00013.24 ETO31760.1 - 7.5e-14 51.1 1.5 1.1e-13 50.6 1.0 1.2 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 ETO31760.1 - 2.2e-10 39.9 2.5 4.3e-10 39.0 1.7 1.5 1 0 0 1 1 1 1 KH domain KH_2 PF07650.12 ETO31760.1 - 0.0032 16.9 2.1 0.0056 16.2 1.2 1.6 1 1 0 1 1 1 1 KH domain KH_4 PF13083.1 ETO31760.1 - 0.0053 16.3 0.9 0.012 15.2 0.6 1.7 1 1 0 1 1 1 1 KH domain KH_1 PF00013.24 ETO31761.1 - 2.4e-07 30.2 0.7 5.3e-07 29.1 0.2 1.9 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 ETO31761.1 - 1.7e-05 24.3 0.7 3.7e-05 23.2 0.5 1.6 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 ETO31761.1 - 0.00047 19.7 0.2 0.0014 18.1 0.0 1.9 2 0 0 2 2 2 1 KH domain KH_2 PF07650.12 ETO31761.1 - 0.072 12.6 0.0 0.072 12.6 0.0 2.4 2 0 0 2 2 2 0 KH domain Period_C PF12114.3 ETO31761.1 - 0.11 12.0 8.1 0.22 11.0 5.6 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Sulfotransfer_3 PF13469.1 ETO31762.1 - 0.0075 17.2 0.5 6.6 7.6 0.0 2.6 2 1 0 2 2 2 2 Sulfotransferase family PCI PF01399.22 ETO31762.1 - 1 9.7 8.8 3.4 8.0 0.5 3.3 4 0 0 4 4 4 0 PCI domain PAS_10 PF13596.1 ETO31763.1 - 0.12 12.7 1.1 0.3 11.3 0.6 1.8 1 1 0 1 1 1 0 PAS domain DUF2431 PF10354.4 ETO31764.1 - 0.027 14.4 2.7 0.078 12.9 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF2431) Spc97_Spc98 PF04130.8 ETO31765.1 - 8.2e-11 40.9 2.3 9.5e-11 40.7 1.6 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family SNF2_N PF00176.18 ETO31766.1 - 1.6e-28 99.4 0.0 1.8e-28 99.2 0.0 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain RdRP_3 PF00998.18 ETO31766.1 - 0.053 12.0 0.0 0.063 11.7 0.0 1.1 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase DNA_pol_E_B PF04042.11 ETO31767.1 - 1.1e-35 122.7 0.0 1.5e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B NOA36 PF06524.7 ETO31768.1 - 1 8.5 9.5 1.6 7.9 6.6 1.4 1 0 0 1 1 1 0 NOA36 protein DUF3537 PF12056.3 ETO31768.1 - 1.4 7.4 3.6 10 4.6 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3537) CYTH PF01928.16 ETO31769.1 - 6.2e-11 42.3 0.2 8.6e-11 41.8 0.1 1.2 1 0 0 1 1 1 1 CYTH domain DUF3474 PF11960.3 ETO31769.1 - 0.092 12.7 0.3 7.3 6.6 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3474) Tn7_Tnp_TnsA_N PF08722.6 ETO31769.1 - 0.31 11.0 4.5 0.89 9.5 0.6 2.5 1 1 0 2 2 2 0 TnsA endonuclease N terminal ATP-synt_F PF01990.12 ETO31772.1 - 0.094 13.1 0.7 0.29 11.5 0.2 1.9 1 1 1 2 2 2 0 ATP synthase (F/14-kDa) subunit DUF3826 PF12875.2 ETO31773.1 - 0.00012 21.8 0.8 0.00018 21.2 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3826) Merozoite_SPAM PF07133.6 ETO31774.1 - 2.8 7.8 8.8 5.5 6.8 0.5 2.1 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) Exo_endo_phos PF03372.18 ETO31775.1 - 2.9e-08 33.9 0.0 3.3e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family GspH PF12019.3 ETO31775.1 - 0.14 12.3 0.1 0.46 10.6 0.0 1.9 2 0 0 2 2 2 0 Type II transport protein GspH GCC2_GCC3 PF07699.8 ETO31775.1 - 0.23 11.0 1.3 20 4.8 0.1 2.4 2 0 0 2 2 2 0 GCC2 and GCC3 ELMO_CED12 PF04727.8 ETO31777.1 - 1.2e-31 109.5 0.2 2.2e-31 108.6 0.1 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family DUF1943 PF09172.6 ETO31778.1 - 0.0035 16.2 1.5 0.0035 16.2 1.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF1943) LEA_2 PF03168.8 ETO31778.1 - 0.019 15.3 4.7 0.059 13.7 3.1 1.9 1 1 0 1 1 1 0 Late embryogenesis abundant protein Trs65 PF12735.2 ETO31778.1 - 0.12 11.6 3.1 0.17 11.1 2.2 1.3 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 Bactofilin PF04519.8 ETO31778.1 - 0.78 9.7 7.8 0.84 9.6 4.2 1.8 1 1 1 2 2 2 0 Polymer-forming cytoskeletal AF-4 PF05110.8 ETO31778.1 - 0.9 7.3 19.0 1 7.1 13.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein A2M_N_2 PF07703.9 ETO31778.1 - 1.6 8.5 11.2 17 5.2 7.8 2.3 1 1 0 1 1 1 0 Alpha-2-macroglobulin family N-terminal region DUF4289 PF14121.1 ETO31778.1 - 2.9 6.1 7.4 3.7 5.8 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4289) DUF2807 PF10988.3 ETO31778.1 - 4.2 6.8 12.2 1.2 8.6 3.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2807) DUF940 PF06082.6 ETO31778.1 - 6.2 5.2 9.6 7.8 4.9 6.6 1.2 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) Hid1 PF12722.2 ETO31778.1 - 8.6 3.8 7.9 8.8 3.8 5.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TFIIA PF03153.8 ETO31778.1 - 9 6.0 17.9 11 5.7 12.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pheromone PF08015.6 ETO31779.1 - 3.9 8.3 7.0 13 6.6 0.0 2.6 2 1 0 2 2 2 0 Fungal mating-type pheromone EIF4E-T PF10477.4 ETO31780.1 - 0.035 12.9 0.6 0.039 12.7 0.4 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E RabGAP-TBC PF00566.13 ETO31781.1 - 0.0019 17.7 0.0 0.0021 17.5 0.0 1.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Choline_sulf_C PF12411.3 ETO31783.1 - 0.084 12.7 0.1 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Choline sulfatase enzyme C terminal Cu-oxidase PF00394.17 ETO31783.1 - 0.15 11.9 2.1 0.24 11.2 1.0 1.6 1 1 0 1 1 1 0 Multicopper oxidase PH PF00169.24 ETO31784.1 - 0.00074 19.6 4.1 0.001 19.2 0.0 2.9 2 1 0 2 2 2 1 PH domain zf-TRAF PF02176.13 ETO31785.1 - 5.9e-06 26.5 5.8 5.9e-06 26.5 4.0 2.6 2 0 0 2 2 2 1 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 ETO31785.1 - 0.028 14.4 9.2 0.18 11.8 0.7 3.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TMEM154 PF15102.1 ETO31785.1 - 0.036 13.7 1.1 0.096 12.3 0.8 1.7 1 0 0 1 1 1 0 TMEM154 protein family OSTbeta PF15048.1 ETO31785.1 - 7.9 6.5 8.8 1.3 9.1 1.9 2.2 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein WD40 PF00400.27 ETO31786.1 - 4e-07 29.6 0.9 8.9e-07 28.5 0.1 2.0 1 1 1 2 2 2 1 WD domain, G-beta repeat DnaJ PF00226.26 ETO31787.1 - 4.4e-12 45.5 5.7 0.00072 19.2 0.4 4.3 2 2 2 4 4 4 3 DnaJ domain RPT PF13446.1 ETO31787.1 - 0.001 18.4 0.1 0.25 10.7 0.0 2.4 2 0 0 2 2 2 2 A repeated domain in UCH-protein CUE PF02845.11 ETO31792.1 - 0.0056 16.1 0.0 0.0093 15.4 0.0 1.4 1 0 0 1 1 1 1 CUE domain ZZ PF00569.12 ETO31792.1 - 0.011 15.2 7.8 0.044 13.3 5.4 2.1 1 1 0 1 1 1 0 Zinc finger, ZZ type Prok-RING_1 PF14446.1 ETO31792.1 - 0.14 11.9 6.4 1.3 8.8 2.3 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 C1_2 PF03107.11 ETO31792.1 - 1.8 8.7 6.0 4.1 7.6 4.2 1.7 1 0 0 1 1 1 0 C1 domain FemAB PF02388.11 ETO31792.1 - 5.4 5.6 12.4 0.37 9.4 3.3 2.1 2 0 0 2 2 2 0 FemAB family APG6 PF04111.7 ETO31792.1 - 8.4 5.3 22.4 1.3 8.0 0.9 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 Pkinase PF00069.20 ETO31793.1 - 6.1e-61 205.8 0.2 1.4e-60 204.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO31793.1 - 3.5e-25 88.5 0.0 2.7e-24 85.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO31793.1 - 0.00015 20.8 0.9 0.00018 20.5 0.0 1.7 2 1 0 2 2 2 1 Kinase-like cNMP_binding PF00027.24 ETO31793.1 - 0.002 17.8 0.0 0.0042 16.8 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain APH PF01636.18 ETO31793.1 - 0.0043 16.8 0.0 0.094 12.4 0.0 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family DUF3474 PF11960.3 ETO31793.1 - 0.89 9.5 9.7 0.51 10.3 2.6 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3474) DDHD PF02862.12 ETO31793.1 - 1.7 8.3 10.1 3.5 7.3 7.0 1.5 1 0 0 1 1 1 0 DDHD domain FGF-BP1 PF06473.7 ETO31793.1 - 2.4 7.7 8.2 4.4 6.8 5.7 1.4 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) cNMP_binding PF00027.24 ETO31794.1 - 5.6e-13 48.5 0.1 1.2e-12 47.4 0.0 1.6 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain MdcE PF06833.6 ETO31794.1 - 0.017 14.3 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 Malonate decarboxylase gamma subunit (MdcE) Cg6151-P PF10233.4 ETO31795.1 - 0.021 14.7 2.0 0.021 14.7 1.4 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein CG6151-P COPI_assoc PF08507.5 ETO31795.1 - 0.42 10.2 11.0 0.72 9.5 7.6 1.4 1 0 0 1 1 1 0 COPI associated protein WD40 PF00400.27 ETO31796.1 - 2.1e-42 141.4 10.8 2.3e-09 36.7 0.7 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO31796.1 - 1e-10 40.4 0.8 0.00038 18.7 0.1 3.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 ERO1 PF04137.10 ETO31797.1 - 8.4e-47 159.9 5.0 9.3e-36 123.5 0.1 2.0 1 1 0 2 2 2 2 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) EMP24_GP25L PF01105.19 ETO31798.1 - 7e-27 94.3 2.6 4e-26 91.8 1.8 2.0 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD ArgK PF03308.11 ETO31798.1 - 0.15 10.8 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 ArgK protein WD40 PF00400.27 ETO31799.1 - 1.5e-16 59.5 5.9 2e-11 43.3 0.6 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat Sof1 PF04158.9 ETO31799.1 - 3.5e-05 23.7 8.2 0.00012 21.9 5.7 1.8 1 1 0 1 1 1 1 Sof1-like domain YajC PF02699.10 ETO31799.1 - 0.063 12.9 8.9 0.48 10.1 0.3 2.7 3 0 0 3 3 3 0 Preprotein translocase subunit YMF19 PF02326.10 ETO31799.1 - 3.1 8.4 7.1 9 6.9 4.9 1.8 1 1 0 1 1 1 0 Plant ATP synthase F0 WD40 PF00400.27 ETO31801.1 - 1.1e-53 177.2 22.9 1.1e-10 41.0 0.2 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO31801.1 - 6.2e-13 47.7 3.6 0.0016 16.6 0.0 5.0 3 2 2 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO31801.1 - 0.00035 19.4 10.2 0.66 8.6 0.1 4.6 2 1 1 4 4 4 4 Nup133 N terminal like WD40 PF00400.27 ETO31803.1 - 1.4e-46 154.7 20.2 7.7e-11 41.4 0.7 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO31803.1 - 4.3e-11 41.6 3.6 7.3e-05 21.0 0.0 5.2 1 1 4 5 5 5 5 Nucleoporin Nup120/160 Apt1 PF10351.4 ETO31807.1 - 2.3e-07 30.0 13.5 1.6e-05 23.9 5.0 2.9 2 1 1 3 3 3 2 Golgi-body localisation protein domain MSG PF02349.10 ETO31808.1 - 6.7 6.7 9.5 2.6 8.0 0.9 2.5 2 0 0 2 2 2 0 Major surface glycoprotein Solute_trans_a PF03619.11 ETO31809.1 - 1.7e-08 34.1 1.9 2.2e-08 33.7 1.3 1.3 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Cation_efflux PF01545.16 ETO31809.1 - 0.015 14.3 0.1 0.019 14.0 0.1 1.3 1 0 0 1 1 1 0 Cation efflux family DUF4149 PF13664.1 ETO31809.1 - 0.039 14.0 4.5 0.76 9.8 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) zf-DHHC PF01529.15 ETO31809.1 - 0.052 12.9 6.3 3.1 7.1 4.4 2.2 1 1 0 1 1 1 0 DHHC palmitoyltransferase DUF1705 PF08019.7 ETO31809.1 - 0.86 9.0 5.1 0.48 9.9 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1705) DUF4173 PF13777.1 ETO31809.1 - 3.7 6.7 6.5 1.7 7.9 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) TF_Otx PF03529.8 ETO31810.1 - 0.027 14.6 0.5 1.4 9.1 0.1 2.4 2 0 0 2 2 2 0 Otx1 transcription factor Voltage_CLC PF00654.15 ETO31811.1 - 4.2e-56 190.4 25.9 5.8e-56 190.0 15.0 2.6 2 1 0 2 2 2 1 Voltage gated chloride channel WEMBL PF05701.6 ETO31811.1 - 5.5 5.3 77.1 0.45 8.9 8.1 3.2 2 1 1 3 3 3 0 Weak chloroplast movement under blue light ThiS PF02597.15 ETO31811.1 - 6.9 7.1 6.0 1.6 9.2 0.1 2.6 2 0 0 2 2 2 0 ThiS family Myosin_tail_1 PF01576.14 ETO31811.1 - 7.1 4.2 88.0 2.6 5.6 36.1 2.4 1 1 1 2 2 2 0 Myosin tail Herpes_env PF01673.13 ETO31812.1 - 0.073 11.6 0.7 0.085 11.3 0.5 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Myosin_head PF00063.16 ETO31813.1 - 6.7e-19 67.4 0.1 2.5e-15 55.6 0.0 2.0 2 0 0 2 2 2 2 Myosin head (motor domain) 3HCDH_N PF02737.13 ETO31814.1 - 8.4e-59 198.2 0.2 1.1e-58 197.8 0.2 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 ETO31814.1 - 1.1e-18 67.3 0.0 2.7e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 ETO31814.1 - 0.00033 20.5 0.4 0.00087 19.1 0.1 1.9 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Phage_int_SAM_3 PF14659.1 ETO31814.1 - 0.00035 20.7 0.8 0.15 12.3 0.1 2.4 1 1 1 2 2 2 2 Phage integrase, N-terminal SAM-like domain NAD_binding_7 PF13241.1 ETO31814.1 - 0.03 14.5 0.1 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding F420_oxidored PF03807.12 ETO31814.1 - 0.033 14.6 0.6 0.075 13.4 0.1 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.16 ETO31814.1 - 0.18 11.6 1.2 1.7 8.5 0.3 2.2 2 0 0 2 2 2 0 ThiF family 2TM PF13239.1 ETO31815.1 - 4.3 7.4 10.7 0.074 13.1 2.0 2.3 3 0 0 3 3 3 0 2TM domain CAP_C PF08603.6 ETO31816.1 - 8.7e-07 28.4 3.1 1.9e-06 27.3 2.2 1.6 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 ETO31816.1 - 0.00091 18.6 5.2 0.0021 17.4 3.6 1.7 1 0 0 1 1 1 1 Tubulin binding cofactor C Zip PF02535.17 ETO31816.1 - 1.1 8.1 5.4 1.7 7.6 3.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_M20 PF01546.23 ETO31817.1 - 5.3e-10 39.1 0.0 5.7e-10 38.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Pepsin-I3 PF06394.8 ETO31817.1 - 0.057 13.0 0.5 0.86 9.3 0.0 2.3 1 1 1 2 2 2 0 Pepsin inhibitor-3-like repeated domain Sel1 PF08238.7 ETO31818.1 - 1.1e-25 89.4 34.1 5.5e-06 26.8 0.2 10.0 11 0 0 11 11 11 6 Sel1 repeat TPR_11 PF13414.1 ETO31818.1 - 3.6e-08 32.9 21.1 0.00017 21.1 1.6 5.6 6 0 0 6 6 6 3 TPR repeat Proteasom_Rpn13 PF04683.8 ETO31818.1 - 0.039 14.0 0.1 0.12 12.4 0.1 1.8 1 0 0 1 1 1 0 Proteasome complex subunit Rpn13 ubiquitin receptor ShK PF01549.19 ETO31818.1 - 0.068 13.5 8.2 0.17 12.2 5.7 1.8 1 0 0 1 1 1 0 ShK domain-like TPR_12 PF13424.1 ETO31818.1 - 0.63 10.0 19.5 0.26 11.2 1.0 5.9 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETO31818.1 - 3.2 7.7 10.2 30 4.7 0.2 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat MIT PF04212.13 ETO31818.1 - 3.7 7.5 8.3 31 4.5 0.0 4.4 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.1 ETO31818.1 - 9.7 6.2 17.3 20 5.2 2.0 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Vac7 PF12751.2 ETO31819.1 - 0.083 11.7 3.2 0.1 11.4 2.2 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 DUF3342 PF11822.3 ETO31820.1 - 0.0051 15.9 0.2 0.0053 15.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) CTNNBL PF08216.6 ETO31820.1 - 0.089 12.3 0.2 0.11 12.1 0.2 1.1 1 0 0 1 1 1 0 Catenin-beta-like, Arm-motif containing nuclear Imm18 PF15566.1 ETO31820.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 18 Plasmid_parti PF01672.11 ETO31820.1 - 1.2 9.6 6.2 5.1 7.5 4.3 1.8 1 1 0 1 1 1 0 Putative plasmid partition protein IPPT PF01715.12 ETO31821.1 - 1.6e-41 141.9 1.6 2.1e-20 72.8 0.0 3.5 2 1 1 3 3 3 3 IPP transferase zf-C2H2_jaz PF12171.3 ETO31821.1 - 2e-05 24.6 2.2 5.7e-05 23.1 1.6 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_17 PF13207.1 ETO31821.1 - 0.0022 18.7 1.9 0.0082 16.9 0.0 2.8 3 1 0 3 3 3 1 AAA domain zf-C2H2_2 PF12756.2 ETO31821.1 - 0.004 17.2 1.9 0.012 15.7 1.3 1.9 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) RNA_helicase PF00910.17 ETO31821.1 - 0.011 15.8 4.5 11 6.2 0.1 4.1 4 0 0 4 4 4 0 RNA helicase AAA_18 PF13238.1 ETO31821.1 - 0.037 14.3 0.0 0.037 14.3 0.0 3.4 4 0 0 4 4 4 0 AAA domain AAA_33 PF13671.1 ETO31821.1 - 0.43 10.4 4.1 8.6 6.2 0.0 3.7 3 2 1 4 4 4 0 AAA domain zf-met PF12874.2 ETO31821.1 - 1.2 9.4 6.1 8.8 6.6 4.3 2.6 1 1 0 1 1 1 0 Zinc-finger of C2H2 type Hist_deacetyl PF00850.14 ETO31822.1 - 1.2e-45 156.1 5.5 4.7e-33 114.8 0.0 2.7 3 0 0 3 3 3 2 Histone deacetylase domain ETRAMP PF09716.5 ETO31822.1 - 1.2 9.0 0.0 1.2 9.0 0.0 3.6 4 0 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) Stork_head PF10264.4 ETO31823.1 - 0.082 13.0 0.1 0.87 9.8 0.0 2.8 3 0 0 3 3 3 0 Winged helix Storkhead-box1 domain SNF2_N PF00176.18 ETO31825.1 - 2e-57 194.2 2.4 2e-57 194.2 1.7 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETO31825.1 - 3.1e-15 55.8 0.1 8.5e-15 54.3 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.19 ETO31825.1 - 2.1e-10 40.0 8.3 0.00012 21.6 2.8 3.9 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.24 ETO31825.1 - 1.6e-07 30.9 0.2 6.3e-07 29.0 0.0 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase RNA_capsid PF03035.9 ETO31825.1 - 0.84 9.3 0.0 0.84 9.3 0.0 3.4 4 1 0 4 4 4 0 Calicivirus putative RNA polymerase/capsid protein Peptidase_C14 PF00656.17 ETO31826.1 - 4.1e-08 33.2 2.1 5e-08 32.9 0.2 2.0 2 0 0 2 2 2 1 Caspase domain Kelch_5 PF13854.1 ETO31826.1 - 7.2e-06 25.8 1.1 0.71 9.8 0.3 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 ETO31826.1 - 5.2e-05 22.7 10.6 0.00022 20.6 0.1 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO31826.1 - 0.00084 19.4 6.6 0.2 11.9 0.2 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO31826.1 - 0.001 18.7 6.3 0.0069 16.1 0.2 4.1 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO31826.1 - 0.0013 18.4 0.0 0.0052 16.5 0.0 2.1 1 0 0 1 1 1 1 Galactose oxidase, central domain WD40 PF00400.27 ETO31827.1 - 3e-59 194.9 28.6 6.6e-13 48.0 0.1 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO31827.1 - 5.9e-12 44.5 10.7 0.00081 17.6 0.1 4.7 1 1 3 4 4 4 4 Nucleoporin Nup120/160 WD40 PF00400.27 ETO31829.1 - 3.5e-59 194.7 31.4 2e-11 43.2 0.6 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO31829.1 - 1.1e-12 46.9 8.8 0.0043 15.2 0.1 5.3 2 2 2 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO31829.1 - 1.1e-05 24.4 13.5 0.048 12.3 0.8 5.1 1 1 3 4 4 4 4 Nup133 N terminal like USP7_C2 PF14533.1 ETO31829.1 - 0.031 13.7 2.1 22 4.3 0.1 4.6 2 2 1 4 4 4 0 Ubiquitin-specific protease C-terminal DUF843 PF05814.6 ETO31829.1 - 0.14 11.9 3.4 0.34 10.7 2.3 1.6 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) NYD-SP28_assoc PF14775.1 ETO31829.1 - 0.42 10.3 3.7 16 5.3 0.0 4.6 5 0 0 5 5 5 0 Sperm tail C-terminal domain WD40 PF00400.27 ETO31830.1 - 5e-64 210.0 26.7 7.4e-11 41.4 0.7 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO31830.1 - 1.3e-06 26.8 6.2 0.13 10.4 0.0 5.2 2 2 0 4 4 4 3 Nucleoporin Nup120/160 HAD PF12710.2 ETO31830.1 - 0.00024 21.3 3.2 0.057 13.5 0.2 3.3 1 1 2 3 3 3 2 haloacid dehalogenase-like hydrolase DIM1 PF02966.11 ETO31830.1 - 0.089 12.3 0.7 0.23 10.9 0.2 1.9 2 0 0 2 2 2 0 Mitosis protein DIM1 Ricin_B_lectin PF00652.17 ETO31830.1 - 1.1 9.2 9.6 2.2 8.2 2.3 3.0 3 0 0 3 3 3 0 Ricin-type beta-trefoil lectin domain TFIIA PF03153.8 ETO31831.1 - 0.0063 16.4 15.1 0.0063 16.4 10.5 2.0 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Nop25 PF09805.4 ETO31831.1 - 8.5 6.4 16.2 12 5.9 0.5 2.3 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) CAP_GLY PF01302.20 ETO31832.1 - 8.2e-08 31.8 1.6 2.7e-07 30.1 0.1 2.4 2 1 0 2 2 2 1 CAP-Gly domain SpoVIF PF14069.1 ETO31834.1 - 0.052 13.2 0.2 0.32 10.7 0.1 2.2 2 0 0 2 2 2 0 Stage VI sporulation protein F Gag_spuma PF03276.9 ETO31836.1 - 1.2 7.3 12.6 1.9 6.6 8.8 1.2 1 0 0 1 1 1 0 Spumavirus gag protein Bud13 PF09736.4 ETO31838.1 - 3.6e-26 92.1 30.1 1.8e-18 67.1 7.0 5.5 2 2 2 4 4 4 2 Pre-mRNA-splicing factor of RES complex DUF3439 PF11921.3 ETO31839.1 - 0.27 10.9 4.8 0.23 11.2 1.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF373 PF04123.8 ETO31839.1 - 0.55 9.1 1.7 6.4 5.6 0.3 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF373) ABC2_membrane_3 PF12698.2 ETO31839.1 - 6.1 5.7 9.8 12 4.8 6.7 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein PDEase_I PF00233.14 ETO31840.1 - 4e-24 85.6 0.0 4.8e-24 85.4 0.0 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Ion_trans PF00520.26 ETO31843.1 - 9.3e-10 38.0 23.0 9.3e-10 38.0 15.9 2.8 3 0 0 3 3 3 1 Ion transport protein Gluconate_2-dh3 PF13618.1 ETO31843.1 - 0.035 14.2 0.1 0.25 11.4 0.0 2.2 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 DUF2207 PF09972.4 ETO31844.1 - 0.013 14.0 3.4 0.016 13.7 2.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Toxin_YhaV PF11663.3 ETO31844.1 - 0.034 13.8 0.7 0.034 13.8 0.5 2.0 2 0 0 2 2 2 0 Toxin with endonuclease activity YhaV Acyltransferase PF01553.16 ETO31844.1 - 0.28 10.6 2.3 0.24 10.8 0.9 1.5 1 1 0 1 1 1 0 Acyltransferase AgrB PF04647.10 ETO31844.1 - 6 5.8 15.7 0.31 10.0 7.3 1.5 2 0 0 2 2 2 0 Accessory gene regulator B PP2C PF00481.16 ETO31845.1 - 1.1e-17 64.3 0.0 1e-13 51.3 0.0 2.3 2 1 0 2 2 2 2 Protein phosphatase 2C SPX PF03105.14 ETO31845.1 - 1.3 8.7 8.5 1.8 8.2 5.9 1.1 1 0 0 1 1 1 0 SPX domain Actin PF00022.14 ETO31847.1 - 2.8e-20 72.0 0.0 3.8e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Actin Actin PF00022.14 ETO31848.1 - 8.6e-51 172.5 0.0 1.1e-50 172.2 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 ETO31848.1 - 0.098 11.2 0.0 0.11 11.0 0.0 1.3 1 0 0 1 1 1 0 MreB/Mbl protein Alpha_adaptin_C PF02296.11 ETO31849.1 - 8.7e-16 57.8 0.0 5.2e-15 55.3 0.0 2.2 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 ETO31849.1 - 2.7e-13 50.2 1.8 9.3e-13 48.5 1.2 1.9 1 0 0 1 1 1 1 Adaptin C-terminal domain AP4E_app_platf PF14807.1 ETO31849.1 - 4.3e-05 23.6 0.0 9.1e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform B2-adapt-app_C PF09066.5 ETO31849.1 - 0.05 13.4 0.0 0.3 10.9 0.0 2.3 2 1 0 2 2 2 0 Beta2-adaptin appendage, C-terminal sub-domain DUF3447 PF11929.3 ETO31850.1 - 0.0006 19.5 1.8 0.0016 18.2 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) TPR_12 PF13424.1 ETO31851.1 - 1.2e-39 134.0 9.0 1.6e-17 63.2 0.2 2.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO31851.1 - 2.2e-23 81.6 19.9 4e-11 42.4 2.1 3.0 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 ETO31851.1 - 2.6e-16 58.1 8.6 0.00021 20.9 0.1 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO31851.1 - 1.4e-14 52.9 19.7 0.00013 21.3 1.6 4.9 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO31851.1 - 4.3e-13 47.9 1.3 1.3e-06 27.7 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO31851.1 - 5.6e-12 44.5 15.0 4.6e-05 22.8 0.2 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO31851.1 - 5.4e-11 42.0 0.0 0.011 15.6 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO31851.1 - 9.9e-05 22.5 3.8 0.58 10.7 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO31851.1 - 0.00012 22.6 0.0 0.97 10.1 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO31851.1 - 0.00019 21.7 0.0 4.8 8.0 0.0 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO31851.1 - 0.00054 19.9 4.3 0.62 10.4 0.3 4.3 4 2 0 4 4 3 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO31851.1 - 0.0013 18.8 2.4 0.23 11.5 0.3 2.8 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.1 ETO31851.1 - 0.0015 17.7 0.7 0.0048 16.0 0.5 1.8 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP MIT PF04212.13 ETO31851.1 - 0.0062 16.3 12.6 1.9 8.4 0.0 5.2 6 0 0 6 6 6 2 MIT (microtubule interacting and transport) domain Sel1 PF08238.7 ETO31851.1 - 0.059 14.0 6.2 7.9 7.2 0.1 3.8 4 0 0 4 4 4 0 Sel1 repeat TPR_3 PF07720.7 ETO31851.1 - 7.1 6.5 10.0 1.6 8.5 0.2 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat Rhomboid PF01694.17 ETO31852.1 - 1.8e-19 70.1 11.5 1.8e-19 70.1 8.0 1.4 2 0 0 2 2 2 1 Rhomboid family DUF1751 PF08551.5 ETO31852.1 - 8.4e-05 22.8 0.6 8.4e-05 22.8 0.4 2.0 3 0 0 3 3 3 1 Eukaryotic integral membrane protein (DUF1751) PCNA_C PF02747.10 ETO31853.1 - 8.5e-50 167.9 0.0 2.2e-49 166.6 0.0 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.13 ETO31853.1 - 5.5e-45 151.9 1.9 9.1e-45 151.2 1.3 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.11 ETO31853.1 - 9e-08 31.2 0.2 1.9e-06 26.8 0.1 2.3 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 ETO31853.1 - 0.00071 18.7 0.1 0.00083 18.5 0.1 1.2 1 0 0 1 1 1 1 Rad9 DUF2064 PF09837.4 ETO31853.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) Solute_trans_a PF03619.11 ETO31854.1 - 0.012 14.9 1.0 0.026 13.8 0.3 1.8 1 1 1 2 2 2 0 Organic solute transporter Ostalpha PT PF04886.7 ETO31855.1 - 9.8e-11 40.7 66.4 4.9e-06 25.7 14.8 5.7 4 2 1 5 5 5 3 PT repeat Glycoprotein_G PF00802.14 ETO31855.1 - 0.12 11.5 38.8 0.14 11.2 6.6 2.9 3 0 0 3 3 3 0 Pneumovirus attachment glycoprotein G DUF4106 PF13388.1 ETO31855.1 - 3.1 6.6 16.1 2.5 6.9 4.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4106) Pkinase PF00069.20 ETO31856.1 - 1.4e-61 207.9 0.0 1.1e-43 149.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO31856.1 - 5.1e-23 81.4 0.0 8.1e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Reprolysin_5 PF13688.1 ETO31857.1 - 1.2e-09 38.3 0.3 3.3e-09 36.9 0.2 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 ETO31857.1 - 2e-08 34.4 0.6 4.5e-08 33.3 0.5 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 ETO31857.1 - 3.8e-07 29.8 2.2 1.1e-06 28.2 1.5 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 ETO31857.1 - 9.1e-07 29.4 0.8 4e-06 27.3 0.6 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Hemopexin PF00045.14 ETO31857.1 - 5.4e-06 26.0 5.2 0.14 11.9 0.0 4.5 4 0 0 4 4 4 2 Hemopexin ESSS PF10183.4 ETO31859.1 - 0.18 12.1 1.7 1.3 9.4 1.2 2.3 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ApoO PF09769.4 ETO31859.1 - 0.27 10.9 4.4 0.61 9.7 3.0 1.5 1 0 0 1 1 1 0 Apolipoprotein O Ion_trans_2 PF07885.11 ETO31860.1 - 1.6e-11 43.7 16.5 8e-11 41.4 0.6 3.7 3 1 1 4 4 4 2 Ion channel Cation_ATPase_C PF00689.16 ETO31860.1 - 0.013 15.0 6.2 0.075 12.5 1.4 2.1 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus Cytochrom_B_N PF00033.14 ETO31860.1 - 0.021 14.2 5.0 0.57 9.4 0.2 2.7 2 1 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB DUF1275 PF06912.6 ETO31860.1 - 0.025 13.7 3.5 0.04 13.1 2.0 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1275) DcuC PF03606.10 ETO31860.1 - 0.043 12.0 1.8 0.056 11.6 0.2 1.8 2 0 0 2 2 2 0 C4-dicarboxylate anaerobic carrier FA_desaturase PF00487.19 ETO31860.1 - 0.58 9.5 4.9 0.6 9.5 2.2 1.9 1 1 0 1 1 1 0 Fatty acid desaturase Exo_endo_phos PF03372.18 ETO31861.1 - 0.0032 17.4 0.0 0.0032 17.4 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Phage_prot_Gp6 PF05133.9 ETO31861.1 - 0.078 11.5 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Phage portal protein, SPP1 Gp6-like Exo_endo_phos_2 PF14529.1 ETO31862.1 - 0.034 13.7 0.0 0.13 11.9 0.0 2.1 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 ETO31862.1 - 0.06 13.2 0.0 0.08 12.8 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Phage_Mu_Gam PF07352.7 ETO31863.1 - 0.00055 19.4 4.1 0.00055 19.4 2.8 2.3 2 0 0 2 2 2 1 Bacteriophage Mu Gam like protein DUF4387 PF14330.1 ETO31863.1 - 0.0068 16.7 0.4 0.024 14.9 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) Reo_sigmaC PF04582.7 ETO31863.1 - 0.56 9.3 4.2 0.82 8.7 2.9 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF4200 PF13863.1 ETO31863.1 - 2.2 8.2 29.7 0.76 9.7 4.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Striatin PF08232.7 ETO31863.1 - 3.7 7.8 16.7 13 6.1 10.2 2.5 1 1 1 2 2 2 0 Striatin family HECT PF00632.20 ETO31864.1 - 4.7e-71 239.5 0.0 2.1e-70 237.3 0.0 2.0 1 1 1 2 2 2 1 HECT-domain (ubiquitin-transferase) TTKRSYEDQ PF10212.4 ETO31866.1 - 0.065 12.1 2.0 0.14 11.0 1.4 1.5 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein Curto_V3 PF07436.6 ETO31866.1 - 0.092 12.8 1.8 0.13 12.4 0.3 1.9 1 1 1 2 2 2 0 Curtovirus V3 protein CaM-KIIN PF15170.1 ETO31867.1 - 0.13 12.3 0.8 0.44 10.5 0.1 2.2 2 0 0 2 2 2 0 Calcium/calmodulin-dependent protein kinase II inhibitor Glyco_transf_92 PF01697.22 ETO31868.1 - 1.9e-06 27.3 6.4 1.9e-06 27.3 4.4 2.2 2 0 0 2 2 2 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.1 ETO31868.1 - 6.2e-05 23.2 4.7 6.2e-05 23.2 3.2 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF972 PF06156.8 ETO31869.1 - 0.054 13.8 3.7 0.14 12.4 2.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF2746 PF10874.3 ETO31870.1 - 0.036 14.2 1.1 0.062 13.4 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) WW PF00397.21 ETO31871.1 - 3.8e-17 61.8 17.6 0.00011 21.9 1.3 4.5 4 0 0 4 4 4 4 WW domain DUF4585 PF15232.1 ETO31871.1 - 0.0069 16.2 0.9 17 5.3 0.0 4.2 4 0 0 4 4 4 1 Domain of unknown function (DUF4585) MAP1B_neuraxin PF00414.12 ETO31871.1 - 5 6.6 10.2 12 5.4 0.1 3.3 3 0 0 3 3 3 0 Neuraxin and MAP1B repeat Mucin PF01456.12 ETO31871.1 - 10 5.9 12.7 15 5.3 8.8 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Sulfotransfer_1 PF00685.22 ETO31872.1 - 0.00029 20.1 4.0 0.0009 18.5 2.7 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.9 ETO31872.1 - 0.0027 17.4 1.1 0.0064 16.1 0.6 1.9 2 1 0 2 2 2 1 Sulfotransferase family SAC3_GANP PF03399.11 ETO31872.1 - 0.027 14.0 1.6 0.096 12.2 1.1 2.0 1 1 0 1 1 1 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Sulfotransfer_3 PF13469.1 ETO31872.1 - 0.047 14.6 0.0 0.11 13.4 0.0 1.6 1 1 0 1 1 1 0 Sulfotransferase family DAO PF01266.19 ETO31873.1 - 2.8e-15 56.0 0.0 2.1e-14 53.2 0.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETO31873.1 - 6.4e-11 42.1 0.2 1.7e-10 40.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 ETO31873.1 - 3.2e-07 29.6 0.1 7.6e-07 28.4 0.1 1.5 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 ETO31873.1 - 6.5e-06 25.4 0.0 1.4e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETO31873.1 - 8.4e-06 26.1 1.2 4.4e-05 23.7 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETO31873.1 - 9.2e-06 24.7 4.9 4.3e-05 22.5 0.4 2.7 3 0 0 3 3 3 1 FAD binding domain Amino_oxidase PF01593.19 ETO31873.1 - 1.8e-05 24.0 0.5 0.00015 21.0 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase GIDA PF01134.17 ETO31873.1 - 5.7e-05 22.1 0.1 0.0012 17.7 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 ETO31873.1 - 0.0001 21.5 0.2 0.00018 20.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 ETO31873.1 - 0.00029 20.7 0.1 0.00077 19.3 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETO31873.1 - 0.00032 20.8 0.1 0.0013 18.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETO31873.1 - 0.00054 18.5 0.2 0.00091 17.8 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.9 ETO31873.1 - 0.013 14.1 0.0 0.019 13.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.9 ETO31873.1 - 0.1 11.9 0.1 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 ETO31873.1 - 0.13 11.3 0.1 3 6.9 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 ETO31873.1 - 0.15 10.9 0.2 0.27 10.1 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 ETO31873.1 - 0.17 11.6 0.1 6.8 6.4 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Exo_endo_phos PF03372.18 ETO31874.1 - 0.014 15.3 0.0 0.041 13.8 0.0 1.8 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF4582 PF15189.1 ETO31874.1 - 0.072 12.3 1.2 1.1 8.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4582) MCM PF00493.18 ETO31875.1 - 6.8e-135 449.1 0.4 6.8e-135 449.1 0.3 1.5 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 ETO31875.1 - 7.6e-16 58.6 0.1 3.6e-15 56.5 0.0 2.2 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 ETO31875.1 - 5.5e-08 32.2 0.0 4.2e-07 29.3 0.0 2.3 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI MCM2_N PF12619.3 ETO31875.1 - 2.1e-05 24.5 6.3 2.1e-05 24.5 4.4 2.6 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 AAA_5 PF07728.9 ETO31875.1 - 5.5e-05 22.9 0.0 0.00013 21.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 ETO31875.1 - 0.00064 19.3 0.0 0.003 17.1 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 ETO31875.1 - 0.0034 16.8 0.1 1.4 8.3 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain Zn-ribbon_8 PF09723.5 ETO31875.1 - 0.11 12.4 0.4 0.28 11.1 0.3 1.7 1 0 0 1 1 1 0 Zinc ribbon domain TPR_12 PF13424.1 ETO31876.1 - 0.0022 17.9 0.0 0.0032 17.3 0.0 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO31876.1 - 0.023 14.2 0.1 0.25 11.0 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 ETO31876.1 - 0.067 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 TPR repeat PUB PF09409.5 ETO31877.1 - 0.029 14.1 0.5 0.029 14.1 0.3 2.7 3 1 0 3 3 3 0 PUB domain DUF2385 PF09539.5 ETO31878.1 - 0.07 13.5 0.7 0.13 12.6 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2385) SAP PF02037.22 ETO31878.1 - 0.11 11.9 0.5 0.18 11.3 0.3 1.3 1 0 0 1 1 1 0 SAP domain Sulfotransfer_1 PF00685.22 ETO31880.1 - 8.7e-35 120.2 4.1 5.5e-18 65.1 0.2 2.3 2 0 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.1 ETO31880.1 - 0.011 16.6 0.1 0.29 12.0 0.0 2.7 1 1 0 2 2 2 0 Sulfotransferase family DBD_Tnp_Mut PF03108.10 ETO31881.1 - 0.0078 15.7 0.3 1.6 8.3 0.0 2.5 2 0 0 2 2 2 2 MuDR family transposase Solute_trans_a PF03619.11 ETO31882.1 - 4.9e-66 222.8 18.2 6.8e-66 222.3 12.6 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF3122 PF11320.3 ETO31882.1 - 0.071 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3122) DsbD PF02683.10 ETO31882.1 - 0.3 10.6 5.9 0.69 9.4 4.1 1.5 1 1 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region NESP55 PF06390.7 ETO31882.1 - 0.5 9.7 6.5 0.74 9.1 4.5 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Baculo_LEF-2 PF03041.9 ETO31884.1 - 0.048 13.3 3.0 0.27 10.8 0.1 2.8 2 1 1 3 3 3 0 lef-2 PARP_regulatory PF01358.13 ETO31885.1 - 0.075 11.6 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 Poly A polymerase regulatory subunit SH3_1 PF00018.23 ETO31886.1 - 3.4e-15 55.1 0.3 6.1e-15 54.3 0.2 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 ETO31886.1 - 1.1e-12 47.3 0.1 2.3e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 ETO31886.1 - 5.1e-12 45.0 0.0 1.1e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain VHP PF02209.14 ETO31886.1 - 1.4e-11 43.8 0.8 2.8e-11 42.8 0.5 1.6 1 0 0 1 1 1 1 Villin headpiece domain LST1 PF05083.8 ETO31886.1 - 0.24 11.4 1.5 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 LST-1 protein RhoGEF PF00621.15 ETO31887.1 - 1.2e-14 54.6 2.3 1.5e-14 54.2 1.6 1.1 1 0 0 1 1 1 1 RhoGEF domain EI24 PF07264.6 ETO31887.1 - 0.0048 16.3 0.4 0.0055 16.1 0.3 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Glycos_trans_3N PF02885.12 ETO31887.1 - 0.052 13.1 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain zf-DHHC PF01529.15 ETO31887.1 - 4.9 6.5 6.8 7.6 5.8 4.7 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase UPF0160 PF03690.8 ETO31888.1 - 3.3e-32 112.1 0.0 3.7e-32 112.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) WD40 PF00400.27 ETO31889.1 - 3.2e-76 248.7 15.5 1.8e-12 46.6 0.0 7.0 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO31889.1 - 9.9e-09 35.1 0.2 1.9e-05 24.4 0.0 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO31889.1 - 8.4e-08 30.9 2.8 0.00039 18.8 0.0 3.1 1 1 2 3 3 3 3 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 ETO31889.1 - 0.0002 20.3 1.0 0.0016 17.3 0.2 2.0 1 1 1 2 2 2 1 Coatomer WD associated region PQQ_2 PF13360.1 ETO31889.1 - 0.0013 18.2 0.1 0.005 16.3 0.1 2.2 1 1 0 1 1 1 1 PQQ-like domain DPPIV_N PF00930.16 ETO31889.1 - 0.0031 16.1 0.0 9.1 4.7 0.0 3.8 1 1 3 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region B_lectin PF01453.19 ETO31889.1 - 0.0033 17.3 1.5 0.022 14.6 0.1 2.8 2 1 1 3 3 3 2 D-mannose binding lectin Ricin_B_lectin PF00652.17 ETO31889.1 - 0.0048 16.9 0.5 0.42 10.6 0.0 3.1 2 2 0 3 3 3 1 Ricin-type beta-trefoil lectin domain Herpes_UL52 PF03121.10 ETO31889.1 - 0.082 12.6 0.1 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Herpesviridae UL52/UL70 DNA primase DUF2415 PF10313.4 ETO31889.1 - 0.13 11.9 0.1 15 5.3 0.0 3.2 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) Proteasome_A_N PF10584.4 ETO31889.1 - 0.16 11.2 1.2 12 5.3 0.0 3.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature DUF1751 PF08551.5 ETO31890.1 - 1.7 9.0 13.3 0.15 12.3 3.2 3.1 3 1 0 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) eIF-3c_N PF05470.7 ETO31891.1 - 6.6e-46 156.5 2.8 1e-45 155.9 1.9 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 ETO31891.1 - 9.2e-08 32.3 0.1 2.6e-07 30.8 0.1 1.8 1 0 0 1 1 1 1 PCI domain Staphostatin_A PF09022.5 ETO31891.1 - 0.0084 15.9 0.1 0.64 9.8 0.0 3.0 3 0 0 3 3 3 1 Staphostatin A Apc3 PF12895.2 ETO31891.1 - 0.044 13.9 0.0 2.1 8.5 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Solute_trans_a PF03619.11 ETO31892.1 - 2.2e-43 148.5 8.4 4.6e-43 147.4 5.8 1.5 1 1 0 1 1 1 1 Organic solute transporter Ostalpha MIP-T3 PF10243.4 ETO31894.1 - 0.13 10.7 13.7 0.16 10.4 9.5 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Nucleo_P87 PF07267.6 ETO31894.1 - 3.5 6.2 8.1 3.9 6.0 5.6 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Daxx PF03344.10 ETO31895.1 - 0.078 11.4 29.0 0.1 11.0 20.1 1.1 1 0 0 1 1 1 0 Daxx Family DUF4386 PF14329.1 ETO31897.1 - 0.0026 17.2 1.7 0.0033 16.9 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4386) zf-CDGSH PF09360.5 ETO31899.1 - 0.0068 16.2 0.7 0.02 14.7 0.5 1.8 1 1 0 1 1 1 1 Iron-binding zinc finger CDGSH type DUF1419 PF07215.6 ETO31899.1 - 0.33 10.8 2.7 0.26 11.1 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1419) WD40 PF00400.27 ETO31901.1 - 7.2e-13 47.8 0.3 1.1e-10 40.9 0.1 2.6 2 1 0 2 2 2 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 ETO31901.1 - 0.087 12.6 0.1 2.4 7.9 0.0 2.7 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Peptidase_C14 PF00656.17 ETO31902.1 - 1.5e-05 24.7 1.6 2.4e-05 24.1 0.3 1.9 2 1 0 2 2 2 1 Caspase domain DUF3186 PF11382.3 ETO31903.1 - 7.3 5.6 6.7 1.6 7.8 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3186) FKBP_C PF00254.23 ETO31904.1 - 1.4e-25 89.1 0.1 2.3e-22 78.8 0.1 2.2 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4163 PF13739.1 ETO31904.1 - 0.0039 17.9 0.0 0.018 15.7 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4163) Late_protein_L2 PF00513.13 ETO31906.1 - 0.4 9.4 5.3 0.48 9.2 3.7 1.2 1 0 0 1 1 1 0 Late Protein L2 WD40 PF00400.27 ETO31907.1 - 9.7e-76 247.1 25.9 2.6e-13 49.2 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO31907.1 - 4.4e-08 31.7 13.6 0.041 12.0 0.7 5.1 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO31907.1 - 2.6e-06 26.4 14.5 0.23 10.1 0.3 5.1 1 1 3 4 4 4 4 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO31907.1 - 0.0046 15.3 6.3 0.29 9.4 0.0 2.9 1 1 1 3 3 3 2 Cytochrome D1 heme domain CoiA PF06054.6 ETO31907.1 - 0.04 12.8 0.0 0.074 11.9 0.0 1.5 1 0 0 1 1 1 0 Competence protein CoiA-like family PQQ_3 PF13570.1 ETO31907.1 - 0.086 13.1 0.3 29 5.0 0.0 3.4 3 0 0 3 3 3 0 PQQ-like domain Peptidase_S9_N PF02897.10 ETO31907.1 - 0.64 8.5 3.6 1.8 7.0 0.0 2.8 3 1 1 4 4 4 0 Prolyl oligopeptidase, N-terminal beta-propeller domain TPR_12 PF13424.1 ETO31908.1 - 4.5e-42 141.8 15.6 1.9e-15 56.5 0.0 4.0 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO31908.1 - 2.3e-18 65.4 0.0 9.4e-06 25.3 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO31908.1 - 2.5e-18 65.4 15.3 7.4e-08 31.9 0.6 3.7 3 1 1 4 4 4 3 TPR repeat TPR_2 PF07719.12 ETO31908.1 - 3.3e-18 64.0 9.5 8.7e-07 28.3 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO31908.1 - 9.2e-17 59.8 19.0 3.4e-09 35.9 0.4 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO31908.1 - 4e-13 48.1 21.6 4e-07 29.3 1.4 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO31908.1 - 1.5e-10 40.0 4.6 0.00011 21.7 0.0 4.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO31908.1 - 5.1e-05 23.4 1.7 0.5 10.9 0.1 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO31908.1 - 0.00016 22.0 0.0 0.91 10.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF2225 PF09986.4 ETO31908.1 - 0.00028 20.4 3.7 0.014 14.8 0.2 2.7 1 1 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_17 PF13431.1 ETO31908.1 - 0.0069 16.5 10.8 0.11 12.7 0.0 4.8 4 1 0 4 4 4 1 Tetratricopeptide repeat NSF PF02071.15 ETO31908.1 - 2.6 9.0 8.3 22 6.2 1.2 4.6 4 0 0 4 4 4 0 Aromatic-di-Alanine (AdAR) repeat MIT PF04212.13 ETO31908.1 - 6.7 6.6 10.6 11 5.9 0.2 4.3 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain SAM_2 PF07647.12 ETO31909.1 - 8.8e-05 22.2 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) G-7-MTase PF12803.2 ETO31909.1 - 0.39 9.7 7.7 0.57 9.2 5.3 1.2 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) Mito_carr PF00153.22 ETO31910.1 - 5.8e-32 109.2 0.0 3e-16 58.8 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Peptidase_C14 PF00656.17 ETO31911.1 - 0.0069 16.1 0.0 0.0088 15.7 0.0 1.3 1 1 0 1 1 1 1 Caspase domain Kelch_6 PF13964.1 ETO31912.1 - 1.2e-05 25.2 1.0 0.043 14.0 0.0 4.2 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 ETO31912.1 - 0.00074 19.0 0.3 0.02 14.4 0.0 3.0 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO31912.1 - 0.0035 17.0 0.1 0.026 14.3 0.0 2.3 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO31912.1 - 0.0061 16.7 0.1 0.082 13.0 0.0 2.7 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO31912.1 - 0.12 12.1 0.1 5.8 6.8 0.0 3.1 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.1 ETO31912.1 - 0.14 12.1 0.4 0.14 12.1 0.2 2.5 3 0 0 3 3 3 0 Kelch motif WD40 PF00400.27 ETO31913.1 - 0.00036 20.3 1.9 0.00078 19.2 1.3 1.6 1 0 0 1 1 1 1 WD domain, G-beta repeat TLP-20 PF06088.6 ETO31913.1 - 0.0077 15.9 1.7 0.012 15.3 1.2 1.3 1 0 0 1 1 1 1 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PBP_sp32 PF07222.7 ETO31913.1 - 0.065 12.3 1.3 0.11 11.6 0.9 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 RXT2_N PF08595.6 ETO31913.1 - 0.23 11.2 4.6 0.37 10.5 3.2 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.7 ETO31913.1 - 0.57 8.0 7.8 0.54 8.1 5.4 1.1 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 ETO31913.1 - 2.5 7.6 10.2 3.8 7.0 7.1 1.4 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 ETO31913.1 - 6.9 5.8 14.0 0.79 8.9 7.0 1.4 2 0 0 2 2 2 0 NOA36 protein La PF05383.12 ETO31914.1 - 1.2e-16 60.2 1.5 1.5e-16 59.8 0.2 1.7 2 0 0 2 2 2 1 La domain PTPS PF01242.14 ETO31914.1 - 0.071 12.8 0.3 0.12 12.0 0.2 1.5 1 1 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase DUF848 PF05852.6 ETO31914.1 - 0.66 9.8 7.7 0.096 12.5 2.8 1.6 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Neur_chan_memb PF02932.11 ETO31915.1 - 1.5 8.6 13.7 2.9 7.7 9.5 1.5 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region V_ATPase_I PF01496.14 ETO31915.1 - 7.6 4.2 11.3 11 3.7 7.8 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LtrA PF06772.6 ETO31916.1 - 1.3e-05 24.3 12.9 1.8e-05 23.8 9.0 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Plasmodium_Vir PF05795.6 ETO31917.1 - 4.4e-05 22.8 2.2 5.9e-05 22.4 1.5 1.3 1 0 0 1 1 1 1 Plasmodium vivax Vir protein DUF2207 PF09972.4 ETO31917.1 - 4.9e-05 22.1 0.3 5.7e-05 21.9 0.2 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Mem_trans PF03547.13 ETO31917.1 - 0.0014 16.9 9.8 0.0018 16.6 6.8 1.2 1 0 0 1 1 1 1 Membrane transport protein VIT1 PF01988.14 ETO31917.1 - 0.0038 16.7 7.5 0.0062 16.0 5.2 1.4 1 1 0 1 1 1 1 VIT family TFIIF_alpha PF05793.7 ETO31917.1 - 0.0066 14.8 25.8 0.0083 14.5 17.9 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Tim54 PF11711.3 ETO31917.1 - 0.017 13.7 3.3 0.021 13.4 2.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NPR3 PF03666.8 ETO31917.1 - 0.023 13.2 9.4 0.029 12.9 6.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Cwf_Cwc_15 PF04889.7 ETO31917.1 - 0.048 13.3 17.2 0.056 13.1 11.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.4 ETO31917.1 - 0.054 12.2 16.0 0.065 11.9 11.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Strabismus PF06638.6 ETO31917.1 - 0.078 11.2 2.4 0.099 10.9 1.7 1.1 1 0 0 1 1 1 0 Strabismus protein Daxx PF03344.10 ETO31917.1 - 0.1 11.0 17.9 0.12 10.8 12.4 1.0 1 0 0 1 1 1 0 Daxx Family Paf1 PF03985.8 ETO31917.1 - 0.3 9.7 23.1 0.36 9.5 16.0 1.1 1 0 0 1 1 1 0 Paf1 BSMAP PF12280.3 ETO31917.1 - 0.35 10.7 6.2 0.83 9.4 4.3 1.7 1 1 0 1 1 1 0 Brain specific membrane anchored protein Vfa1 PF08432.5 ETO31917.1 - 0.45 10.5 17.0 0.58 10.1 11.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CKAP2_C PF15297.1 ETO31917.1 - 0.5 9.1 12.7 0.65 8.7 8.8 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus GAGA_bind PF06217.7 ETO31917.1 - 0.63 9.9 13.0 0.7 9.7 9.0 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family NARP1 PF12569.3 ETO31917.1 - 0.76 8.4 14.3 0.93 8.1 9.9 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DARPP-32 PF05395.7 ETO31917.1 - 1.2 9.2 16.1 1.5 8.9 11.1 1.2 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 BTV_NS2 PF04514.7 ETO31917.1 - 1.4 7.7 11.7 1.7 7.4 8.1 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 HSP90 PF00183.13 ETO31917.1 - 1.5 7.1 19.8 1.9 6.7 13.7 1.1 1 0 0 1 1 1 0 Hsp90 protein Prog_receptor PF02161.10 ETO31917.1 - 1.7 7.4 6.4 1.9 7.2 4.5 1.1 1 0 0 1 1 1 0 Progesterone receptor CobT PF06213.7 ETO31917.1 - 2.3 7.2 17.9 2.7 7.0 12.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2201_N PF13203.1 ETO31917.1 - 3 6.9 11.4 3.6 6.6 7.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain MFMR PF07777.6 ETO31917.1 - 3.3 7.5 14.4 4.6 7.1 10.0 1.1 1 0 0 1 1 1 0 G-box binding protein MFMR RP-C_C PF11800.3 ETO31917.1 - 3.7 7.1 8.1 4.9 6.7 5.6 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region FLO_LFY PF01698.11 ETO31917.1 - 4.6 5.9 15.0 5.5 5.7 10.4 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF3464 PF11947.3 ETO31917.1 - 5.6 6.4 9.7 14 5.1 6.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3464) Prog_receptor PF02161.10 ETO31918.1 - 0.047 12.5 1.3 0.051 12.4 0.9 1.1 1 0 0 1 1 1 0 Progesterone receptor WD40 PF00400.27 ETO31920.1 - 4.8e-25 86.4 3.5 2.8e-11 42.8 0.5 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO31920.1 - 0.021 13.0 0.1 0.16 10.0 0.0 2.2 2 1 0 2 2 2 0 Nucleoporin Nup120/160 WD40 PF00400.27 ETO31921.1 - 9.5e-54 177.4 24.0 1.1e-10 41.0 0.8 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO31921.1 - 1.9e-10 39.5 7.1 0.00012 20.3 0.1 4.6 1 1 3 4 4 4 3 Nucleoporin Nup120/160 DUF2559 PF10832.3 ETO31921.1 - 2.3 8.0 3.6 9.6 6.0 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2559) WD40 PF00400.27 ETO31922.1 - 7.7e-31 104.8 14.0 1.1e-10 40.9 0.2 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO31922.1 - 2.5e-07 29.2 1.1 0.00019 19.7 0.1 3.0 2 1 0 3 3 3 3 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO31922.1 - 0.0045 16.3 4.1 0.008 15.5 2.8 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4221) DIM1 PF02966.11 ETO31922.1 - 5.3 6.5 5.9 12 5.4 0.3 2.2 1 1 1 2 2 2 0 Mitosis protein DIM1 HEAT PF02985.17 ETO31923.1 - 0.003 17.4 0.4 1 9.6 0.0 3.7 4 0 0 4 4 4 1 HEAT repeat DnaB PF00772.16 ETO31923.1 - 0.014 15.2 0.2 0.32 10.8 0.1 2.3 2 0 0 2 2 2 0 DnaB-like helicase N terminal domain Cnd1 PF12717.2 ETO31923.1 - 0.014 15.2 1.0 0.25 11.1 0.0 2.1 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 AAA PF00004.24 ETO31923.1 - 0.017 15.3 0.3 0.034 14.3 0.2 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Eapp_C PF10238.4 ETO31924.1 - 0.0025 17.7 0.5 0.0028 17.5 0.3 1.2 1 0 0 1 1 1 1 E2F-associated phosphoprotein Atrophin-1 PF03154.10 ETO31924.1 - 0.14 10.2 2.8 0.17 9.9 1.9 1.0 1 0 0 1 1 1 0 Atrophin-1 family DNA_pol_phi PF04931.8 ETO31924.1 - 0.15 9.8 4.5 0.19 9.4 3.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF3043 PF11241.3 ETO31927.1 - 2.3 7.7 3.5 7.1 6.1 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) M_domain PF12938.2 ETO31928.1 - 1.1 8.9 10.3 1.6 8.4 7.1 1.3 1 1 0 1 1 1 0 M domain of GW182 Kei1 PF08552.6 ETO31929.1 - 4.4e-05 23.2 1.3 0.013 15.1 0.1 2.1 2 0 0 2 2 2 2 Inositolphosphorylceramide synthase subunit Kei1 Nucleoside_tran PF01733.13 ETO31929.1 - 0.0037 16.4 0.1 0.0055 15.9 0.1 1.3 1 0 0 1 1 1 1 Nucleoside transporter DUF912 PF06024.7 ETO31929.1 - 1.1 9.3 4.3 0.85 9.7 1.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1754 PF08555.5 ETO31929.1 - 7 7.3 13.8 0.3 11.7 2.6 2.2 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Acetyltransf_CG PF14542.1 ETO31930.1 - 5.1e-12 45.5 0.1 7.2e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.1 ETO31930.1 - 8.7e-06 25.8 0.0 1.3e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETO31930.1 - 0.021 14.5 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_1 PF00583.19 ETO31930.1 - 0.024 14.6 0.0 0.033 14.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 ETO31930.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain GnsAB PF08178.6 ETO31930.1 - 0.081 12.5 0.1 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 GnsA/GnsB family Acetyltransf_9 PF13527.1 ETO31930.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain SAM_2 PF07647.12 ETO31931.1 - 8e-11 41.6 0.3 1.8e-10 40.5 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO31931.1 - 5.7e-08 32.8 0.5 1e-07 31.9 0.4 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SlyX PF04102.7 ETO31931.1 - 0.0038 17.5 11.5 0.0052 17.1 2.9 3.1 2 1 1 3 3 3 1 SlyX Med11 PF10280.4 ETO31931.1 - 0.02 14.9 1.4 0.02 14.9 1.0 1.8 2 0 0 2 2 2 0 Mediator complex protein bZIP_1 PF00170.16 ETO31931.1 - 0.024 14.5 3.6 0.024 14.5 2.5 2.5 2 0 0 2 2 2 0 bZIP transcription factor DivIC PF04977.10 ETO31931.1 - 0.1 12.0 2.1 0.32 10.5 1.4 1.9 1 0 0 1 1 1 0 Septum formation initiator Fmp27_WPPW PF10359.4 ETO31931.1 - 0.12 10.7 6.5 0.025 12.9 2.4 1.4 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain HALZ PF02183.13 ETO31931.1 - 0.18 11.5 4.9 0.15 11.8 1.6 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF342 PF03961.8 ETO31931.1 - 0.22 9.9 7.8 5.3 5.3 5.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF342) WD40_alt PF14077.1 ETO31931.1 - 0.26 10.9 2.5 0.48 10.0 0.2 2.4 2 0 0 2 2 2 0 Alternative WD40 repeat motif V_ATPase_I PF01496.14 ETO31931.1 - 0.27 9.0 5.2 0.19 9.5 2.1 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Allexi_40kDa PF05549.6 ETO31931.1 - 0.29 10.4 5.1 0.093 12.0 1.8 1.5 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF16 PF01519.11 ETO31931.1 - 0.51 10.5 6.1 0.6 10.3 2.5 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF106 PF01956.11 ETO31931.1 - 0.75 9.3 2.8 1.7 8.1 1.9 1.6 1 0 0 1 1 1 0 Integral membrane protein DUF106 Orbi_VP5 PF00901.12 ETO31931.1 - 0.81 7.8 8.0 0.43 8.7 3.6 1.7 2 0 0 2 2 2 0 Orbivirus outer capsid protein VP5 DUF607 PF04678.8 ETO31931.1 - 1.2 9.0 4.0 0.55 10.1 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF607 Nup54 PF13874.1 ETO31931.1 - 1.2 8.8 8.5 0.76 9.4 1.7 2.5 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Fib_alpha PF08702.5 ETO31931.1 - 1.9 8.6 9.8 0.5 10.4 2.6 2.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Syntaxin PF00804.20 ETO31931.1 - 2.7 8.2 12.8 7.4 6.7 6.7 2.4 2 0 0 2 2 2 0 Syntaxin PEP-utilisers_N PF05524.8 ETO31931.1 - 4 7.2 6.2 33 4.2 1.4 2.7 2 1 1 3 3 3 0 PEP-utilising enzyme, N-terminal Striatin PF08232.7 ETO31931.1 - 4.9 7.4 13.1 0.31 11.3 3.9 2.5 2 1 0 3 3 3 0 Striatin family Prefoldin PF02996.12 ETO31931.1 - 5.5 6.6 10.7 0.55 9.8 2.3 2.6 2 1 1 3 3 3 0 Prefoldin subunit Planc_extracel PF07595.7 ETO31932.1 - 0.12 12.0 0.8 2.3 8.0 0.0 3.2 3 0 0 3 3 3 0 Planctomycete extracellular GlcNAc PF11397.3 ETO31933.1 - 9.7e-20 70.9 0.4 4.9e-19 68.6 0.3 1.8 1 1 0 1 1 1 1 Glycosyltransferase (GlcNAc) Kinesin PF00225.18 ETO31937.1 - 1.1e-29 103.2 0.2 1.1e-29 103.2 0.1 1.9 2 0 0 2 2 2 1 Kinesin motor domain DUF3585 PF12130.3 ETO31937.1 - 0.026 14.3 2.7 0.21 11.4 2.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3585) Striatin PF08232.7 ETO31937.1 - 0.073 13.3 8.3 0.049 13.9 3.9 2.0 2 0 0 2 2 2 0 Striatin family ATP-synt_D PF01813.12 ETO31939.1 - 3.8e-25 88.5 0.4 5.7e-25 88.0 0.3 1.2 1 0 0 1 1 1 1 ATP synthase subunit D Methyltransf_11 PF08241.7 ETO31941.1 - 1.2e-15 57.7 0.1 2.8e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO31941.1 - 4.9e-15 55.4 0.2 1.2e-14 54.1 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETO31941.1 - 1.1e-13 51.2 0.1 1.9e-13 50.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETO31941.1 - 1.3e-10 41.5 0.1 2.7e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO31941.1 - 2.2e-09 37.6 0.1 6.7e-09 36.1 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETO31941.1 - 1.6e-08 33.9 0.1 2.9e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 ETO31941.1 - 3.9e-08 33.8 0.1 1.1e-07 32.4 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 ETO31941.1 - 6.3e-08 32.2 0.2 1.2e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 ETO31941.1 - 7.1e-07 29.2 0.0 1.4e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 ETO31941.1 - 0.00012 21.7 0.8 0.00043 19.9 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain DREV PF05219.7 ETO31941.1 - 0.00065 18.6 0.1 0.0011 17.9 0.1 1.3 1 0 0 1 1 1 1 DREV methyltransferase MTS PF05175.9 ETO31941.1 - 0.016 14.5 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain NodS PF05401.6 ETO31941.1 - 0.021 14.2 0.0 0.04 13.2 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_29 PF03141.11 ETO31941.1 - 0.026 12.8 0.1 0.026 12.8 0.0 2.2 3 0 0 3 3 3 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DEAD PF00270.24 ETO31942.1 - 1.4e-14 53.9 0.1 4.3e-14 52.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETO31942.1 - 2.6e-11 43.1 0.0 9.3e-11 41.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RQC PF09382.5 ETO31942.1 - 8e-07 28.7 1.7 1.2e-06 28.1 0.2 2.0 2 0 0 2 2 2 1 RQC domain Protocadherin PF08374.6 ETO31942.1 - 6.9 6.2 15.3 14 5.2 10.6 1.5 1 0 0 1 1 1 0 Protocadherin 4HB_MCP_1 PF12729.2 ETO31943.1 - 0.0079 15.5 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction GPS PF01825.16 ETO31944.1 - 9.1e-10 38.4 6.6 5.2e-09 36.0 4.6 2.5 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain DUF2847 PF11009.3 ETO31945.1 - 0.019 14.5 1.1 0.021 14.4 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2847) MSC PF09402.5 ETO31945.1 - 0.024 13.3 2.8 0.033 12.9 2.0 1.0 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain DUF4110 PF13422.1 ETO31945.1 - 0.072 12.9 4.8 0.14 11.9 2.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4110) ResIII PF04851.10 ETO31946.1 - 2e-06 27.7 0.0 3.1e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 ETO31946.1 - 0.00035 20.1 0.0 0.00052 19.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.1 ETO31946.1 - 0.0024 17.5 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain DEAD_2 PF06733.10 ETO31946.1 - 0.0061 15.9 6.5 0.029 13.7 0.1 2.8 3 0 0 3 3 3 2 DEAD_2 DUF853 PF05872.7 ETO31946.1 - 0.0087 14.4 0.0 0.012 13.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) AAA_11 PF13086.1 ETO31946.1 - 0.0098 15.4 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain Ureide_permease PF07168.6 ETO31947.1 - 4 6.0 4.4 2.2 6.8 1.4 1.8 1 1 0 1 1 1 0 Ureide permease Caldesmon PF02029.10 ETO31948.1 - 0.36 9.2 46.9 0.4 9.0 32.5 1.0 1 0 0 1 1 1 0 Caldesmon Nop14 PF04147.7 ETO31948.1 - 0.39 8.5 56.6 0.49 8.2 39.2 1.3 1 0 0 1 1 1 0 Nop14-like family Utp14 PF04615.8 ETO31948.1 - 1.7 6.6 44.5 2 6.4 30.8 1.0 1 0 0 1 1 1 0 Utp14 protein DUF262 PF03235.9 ETO31948.1 - 1.8 8.5 12.5 1.9 8.3 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 Mpp10 PF04006.7 ETO31948.1 - 3.5 5.8 54.6 4.7 5.4 37.9 1.2 1 0 0 1 1 1 0 Mpp10 protein Mitofilin PF09731.4 ETO31948.1 - 5 5.6 29.6 5.3 5.5 20.5 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein YL1 PF05764.8 ETO31949.1 - 0.0013 18.3 4.7 0.0016 18.0 3.3 1.3 1 0 0 1 1 1 1 YL1 nuclear protein Ank_4 PF13637.1 ETO31950.1 - 4.3e-11 43.0 0.3 1.6e-07 31.6 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO31950.1 - 1.7e-10 40.7 0.1 5.7e-08 32.7 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO31950.1 - 1.9e-07 31.3 0.0 3.4e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO31950.1 - 6.5e-07 28.8 0.0 0.026 14.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 ETO31950.1 - 1.4e-06 27.9 0.0 0.0026 17.8 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat 2OG-FeII_Oxy_3 PF13640.1 ETO31953.1 - 1.8e-06 28.3 0.0 3.7e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 ETO31953.1 - 0.0032 17.7 0.0 0.009 16.2 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Tet_JBP PF12851.2 ETO31953.1 - 0.016 14.5 0.0 0.033 13.4 0.0 1.6 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily M11L PF11099.3 ETO31953.1 - 0.02 14.6 1.5 0.039 13.7 0.1 2.2 2 1 0 2 2 2 0 Apoptosis regulator M11L like TPR_11 PF13414.1 ETO31954.1 - 3.7e-16 58.5 5.5 5.1e-16 58.0 3.8 1.2 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 ETO31954.1 - 8.3e-16 56.8 10.9 1.2e-08 34.2 1.2 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO31954.1 - 3.3e-15 55.7 1.7 3.9e-15 55.5 1.2 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO31954.1 - 9e-14 50.2 5.1 1.3e-07 30.9 0.3 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO31954.1 - 6.1e-12 44.3 1.1 6.5e-05 22.4 0.1 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO31954.1 - 4e-11 41.8 10.7 7.1e-06 25.4 1.9 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO31954.1 - 4.1e-08 33.1 0.1 0.0047 17.3 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat RPN7 PF10602.4 ETO31954.1 - 1.7e-06 27.5 1.1 0.0018 17.7 0.3 2.0 1 1 1 2 2 2 2 26S proteasome subunit RPN7 TPR_10 PF13374.1 ETO31954.1 - 2e-06 27.5 3.0 0.017 15.0 0.3 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO31954.1 - 3.9e-06 26.6 7.3 0.034 14.3 0.2 3.4 2 1 0 3 3 3 2 Tetratricopeptide repeat SNAP PF14938.1 ETO31954.1 - 2.4e-05 23.6 2.8 9e-05 21.7 1.9 1.7 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_14 PF13428.1 ETO31954.1 - 3.4e-05 24.0 0.0 0.082 13.5 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO31954.1 - 6.5e-05 23.4 0.1 0.0011 19.5 0.1 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_5 PF12688.2 ETO31954.1 - 0.0007 19.6 0.1 0.002 18.1 0.0 1.7 1 1 0 1 1 1 1 Tetratrico peptide repeat Apc3 PF12895.2 ETO31954.1 - 0.015 15.4 3.1 0.21 11.7 2.1 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 ETO31954.1 - 0.024 14.5 1.5 5 7.3 0.0 2.3 2 0 0 2 2 2 0 PPR repeat MIT PF04212.13 ETO31954.1 - 0.029 14.2 2.3 3.6 7.5 0.2 2.2 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.1 ETO31954.1 - 0.047 14.0 0.3 0.1 12.9 0.2 1.5 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_21 PF09976.4 ETO31954.1 - 0.099 12.5 0.6 2.7 7.9 0.2 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF2225 PF09986.4 ETO31954.1 - 0.13 11.7 2.5 0.32 10.4 1.7 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) PPR_2 PF13041.1 ETO31954.1 - 0.13 12.2 1.8 6.8 6.7 0.0 2.2 2 0 0 2 2 2 0 PPR repeat family NSF PF02071.15 ETO31954.1 - 0.22 12.1 3.7 6.3 7.8 0.1 3.0 3 0 0 3 3 2 0 Aromatic-di-Alanine (AdAR) repeat HATPase_c_5 PF14501.1 ETO31954.1 - 0.33 10.6 3.6 3.2 7.5 1.3 2.3 1 1 1 2 2 2 0 GHKL domain TPR_3 PF07720.7 ETO31954.1 - 0.63 9.9 3.6 0.37 10.6 0.8 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Sel1 PF08238.7 ETO31954.1 - 0.92 10.2 3.3 2 9.1 0.3 2.5 2 2 0 2 2 2 0 Sel1 repeat Pkinase PF00069.20 ETO31955.1 - 3e-37 128.2 0.0 1.1e-24 87.0 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO31955.1 - 1.4e-24 86.5 0.0 3.1e-17 62.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase SelP_N PF04592.9 ETO31955.1 - 0.069 12.5 11.2 0.1 11.9 7.7 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 ETO31955.1 - 0.072 12.0 2.0 0.087 11.8 1.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter ATP11 PF06644.6 ETO31956.1 - 1.2e-12 47.9 0.6 1.5e-12 47.6 0.4 1.1 1 0 0 1 1 1 1 ATP11 protein Corona_NS2 PF04753.7 ETO31956.1 - 0.078 12.9 0.4 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 Coronavirus non-structural protein NS2 UNC45-central PF11701.3 ETO31956.1 - 0.11 12.1 0.1 0.15 11.6 0.1 1.3 1 1 0 1 1 1 0 Myosin-binding striated muscle assembly central WD40 PF00400.27 ETO31957.1 - 3.1e-63 207.5 0.7 1.7e-13 49.8 0.0 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO31957.1 - 8e-12 45.2 0.0 2.8e-07 30.4 0.0 2.7 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO31957.1 - 6.7e-10 37.7 0.5 0.041 12.0 0.0 4.0 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO31957.1 - 1.5e-05 23.4 0.0 0.0027 16.0 0.0 2.5 1 1 1 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.7 ETO31957.1 - 3.3e-05 23.4 2.6 4.5 7.0 0.0 5.0 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO31957.1 - 3.3e-05 23.4 0.0 0.00033 20.1 0.0 2.0 1 1 1 2 2 2 1 PQQ-like domain Nbas_N PF15492.1 ETO31957.1 - 0.00031 19.9 1.0 0.66 9.0 0.0 3.7 1 1 4 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 ETO31957.1 - 0.00044 19.4 2.9 17 4.8 0.0 5.0 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Coatomer_WDAD PF04053.9 ETO31957.1 - 0.0054 15.5 0.0 0.045 12.5 0.0 2.2 1 1 2 3 3 3 1 Coatomer WD associated region DUF4337 PF14235.1 ETO31958.1 - 1.7 8.4 9.2 2 8.2 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) adh_short PF00106.20 ETO31959.1 - 1.4e-28 99.9 0.0 1.7e-28 99.6 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETO31959.1 - 7.2e-12 45.3 0.0 9.2e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETO31959.1 - 4.6e-10 39.6 0.0 5.9e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 ETO31959.1 - 1e-05 25.5 0.0 2.7e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETO31959.1 - 0.00072 19.0 0.0 0.0029 17.0 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETO31959.1 - 0.0071 15.0 0.1 0.0094 14.6 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Rifin_STEVOR PF02009.11 ETO31959.1 - 0.0082 15.8 2.9 0.01 15.4 2.0 1.1 1 0 0 1 1 1 1 Rifin/stevor family Eno-Rase_NADH_b PF12242.3 ETO31959.1 - 0.015 15.0 0.5 0.057 13.2 0.0 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 ETO31959.1 - 0.04 13.1 0.0 0.078 12.2 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family tRNA_bind_2 PF13725.1 ETO31960.1 - 4.6 7.4 7.2 2.8 8.0 1.3 2.5 1 1 1 2 2 2 0 Possible tRNA binding domain WD40 PF00400.27 ETO31961.1 - 7.9e-64 209.4 19.4 2.5e-11 43.0 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO31961.1 - 9.1e-09 33.9 5.6 0.012 13.7 0.1 4.5 1 1 3 4 4 4 4 Nucleoporin Nup120/160 WD40 PF00400.27 ETO31962.1 - 2.3e-55 182.5 23.2 6.3e-11 41.7 0.0 9.0 9 1 0 9 9 9 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO31962.1 - 1.5e-11 43.1 10.6 1.1e-05 23.8 0.4 5.3 2 2 4 6 6 6 5 Nucleoporin Nup120/160 WD40 PF00400.27 ETO31964.1 - 7e-63 206.4 25.4 5.1e-11 41.9 0.4 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO31964.1 - 6.5e-10 37.7 4.3 0.0065 14.6 0.7 5.7 1 1 3 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO31964.1 - 0.00082 18.2 10.9 0.19 10.4 0.3 4.8 1 1 2 3 3 3 2 Nup133 N terminal like DUF1900 PF08954.6 ETO31964.1 - 0.0022 17.5 0.3 6.5 6.2 0.0 3.8 4 0 0 4 4 4 2 Domain of unknown function (DUF1900) Kelch_6 PF13964.1 ETO31964.1 - 0.45 10.7 8.9 32 4.9 0.1 4.8 4 0 0 4 4 4 0 Kelch motif HAD PF12710.2 ETO31964.1 - 1.3 9.1 3.8 4.8 7.2 0.0 3.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase WD40 PF00400.27 ETO31965.1 - 1.3e-65 215.0 29.4 4.4e-12 45.3 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO31965.1 - 9.4e-07 27.3 5.6 1.4 6.9 0.0 5.6 2 1 4 6 6 6 5 Nucleoporin Nup120/160 Kelch_5 PF13854.1 ETO31966.1 - 7.7e-05 22.5 3.8 0.65 10.0 0.0 4.5 4 1 1 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO31966.1 - 0.00083 19.0 1.2 3.1 7.7 0.0 3.9 3 1 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO31966.1 - 0.0015 18.6 0.8 5.2 7.4 0.1 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 ETO31966.1 - 0.0058 16.1 1.2 0.95 9.0 0.2 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 ETO31966.1 - 0.069 13.3 0.2 5.6 7.2 0.0 3.0 3 0 0 3 3 3 0 Galactose oxidase, central domain Pkinase PF00069.20 ETO31967.1 - 1.1e-13 50.9 0.2 1.6e-13 50.3 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO31967.1 - 7.3e-07 28.5 0.2 9.4e-07 28.1 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Viral_DNA_Zn_bi PF03728.8 ETO31967.1 - 0.79 9.8 4.0 1.2 9.2 2.8 1.3 1 0 0 1 1 1 0 Viral DNA-binding protein, zinc binding domain Pkinase PF00069.20 ETO31968.1 - 3.1e-23 82.2 0.1 1.1e-22 80.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO31968.1 - 1e-08 34.5 0.1 1.7e-07 30.6 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase KA1 PF02149.14 ETO31968.1 - 0.064 12.7 0.1 0.57 9.6 0.0 2.2 2 0 0 2 2 2 0 Kinase associated domain 1 Choline_transpo PF04515.7 ETO31969.1 - 2.2e-42 144.9 31.7 3.6e-42 144.2 19.3 3.0 2 1 0 2 2 2 1 Plasma-membrane choline transporter Iron_permease PF04120.7 ETO31969.1 - 0.00034 20.1 0.0 0.00075 19.0 0.0 1.6 1 0 0 1 1 1 1 Low affinity iron permease FixH PF05751.6 ETO31969.1 - 0.029 14.2 0.0 0.093 12.5 0.0 1.9 1 0 0 1 1 1 0 FixH DUF95 PF01944.12 ETO31970.1 - 0.097 12.3 0.9 1.2 8.7 0.8 2.0 1 1 1 2 2 2 0 Integral membrane protein DUF95 OATP PF03137.15 ETO31970.1 - 0.65 7.9 4.4 0.87 7.5 3.0 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF3043 PF11241.3 ETO31970.1 - 6 6.4 6.1 9.1 5.8 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) SET PF00856.23 ETO31971.1 - 3.7e-29 102.1 0.2 3.7e-29 102.1 0.2 3.6 2 1 0 2 2 2 1 SET domain CobT PF06213.7 ETO31972.1 - 0.56 9.2 14.3 0.66 9.0 9.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2457 PF10446.4 ETO31972.1 - 0.66 8.6 16.1 0.75 8.4 11.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 ETO31972.1 - 0.75 8.2 15.6 0.81 8.1 10.8 1.2 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 ETO31972.1 - 1.1 7.2 11.0 1 7.2 7.6 1.2 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.12 ETO31972.1 - 5.5 6.7 9.0 6.4 6.5 6.2 1.1 1 0 0 1 1 1 0 DDHD domain Baculo_LEF-2 PF03041.9 ETO31972.1 - 6.8 6.3 7.0 0.23 11.1 0.2 1.8 2 0 0 2 2 2 0 lef-2 GAGA_bind PF06217.7 ETO31972.1 - 8.4 6.2 8.8 9.1 6.1 6.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family WD40 PF00400.27 ETO31974.1 - 5.1e-12 45.1 4.2 0.00033 20.4 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat IKI3 PF04762.7 ETO31974.1 - 0.0018 16.1 0.1 0.031 12.0 0.1 2.3 1 1 1 2 2 2 1 IKI3 family TFIIIC_delta PF12657.2 ETO31974.1 - 0.029 14.0 0.4 0.91 9.2 0.0 2.5 2 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term PQQ PF01011.16 ETO31974.1 - 0.076 12.5 0.3 0.86 9.2 0.0 2.9 3 1 0 3 3 3 0 PQQ enzyme repeat PQQ_2 PF13360.1 ETO31974.1 - 0.097 12.1 0.0 1.7 8.0 0.0 2.2 1 1 1 2 2 2 0 PQQ-like domain Peptidase_C12 PF01088.16 ETO31975.1 - 1.3e-53 181.3 0.0 2.3e-53 180.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 SNARE_assoc PF09335.6 ETO31976.1 - 7.3e-10 39.1 6.7 7.3e-10 39.1 4.6 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein SYCE1 PF15233.1 ETO31978.1 - 0.12 12.3 0.7 2.2 8.2 0.0 2.1 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 UQ_con PF00179.21 ETO31979.1 - 5.7e-28 97.0 1.1 1.1e-27 96.1 0.7 1.6 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 ETO31979.1 - 0.00021 21.1 0.0 0.00041 20.2 0.0 1.5 1 0 0 1 1 1 1 RWD domain Nop14 PF04147.7 ETO31979.1 - 0.017 13.0 20.7 0.023 12.6 14.3 1.2 1 0 0 1 1 1 0 Nop14-like family RNA_replicase_B PF03431.8 ETO31979.1 - 0.092 10.9 1.5 0.12 10.5 1.0 1.1 1 0 0 1 1 1 0 RNA replicase, beta-chain NARP1 PF12569.3 ETO31979.1 - 0.11 11.2 13.8 0.14 10.9 9.6 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CDC45 PF02724.9 ETO31979.1 - 0.12 10.4 26.8 0.17 9.8 18.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 ETO31979.1 - 0.24 9.0 9.6 0.21 9.2 6.6 1.1 1 0 0 1 1 1 0 Ycf1 Trypan_PARP PF05887.6 ETO31979.1 - 0.36 10.6 11.3 0.5 10.1 7.8 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Phyto_Pns9_10 PF05878.6 ETO31979.1 - 0.37 9.7 11.6 0.51 9.3 8.1 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 eIF-3c_N PF05470.7 ETO31979.1 - 0.83 7.6 18.5 1.2 7.1 12.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Zip PF02535.17 ETO31979.1 - 3.6 6.4 7.7 4.4 6.2 5.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2201_N PF13203.1 ETO31979.1 - 6.4 5.8 13.1 8.4 5.4 9.1 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain CENP-B_dimeris PF09026.5 ETO31980.1 - 0.035 14.3 0.0 0.039 14.1 0.0 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HxlR PF01638.12 ETO31981.1 - 0.013 15.1 0.1 0.047 13.3 0.0 1.9 2 1 0 2 2 2 0 HxlR-like helix-turn-helix DUF694 PF05107.7 ETO31983.1 - 0.13 11.4 3.6 0.16 11.1 2.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF694) GAGA_bind PF06217.7 ETO31983.1 - 0.31 10.9 6.3 0.37 10.7 4.3 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Choline_sulf_C PF12411.3 ETO31984.1 - 0.023 14.4 0.1 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 Choline sulfatase enzyme C terminal IcmL PF11393.3 ETO31984.1 - 5.2 7.0 9.2 0.14 12.1 1.0 2.2 2 0 0 2 2 2 0 Macrophage killing protein with similarity to conjugation protein MOR2-PAG1_C PF14225.1 ETO31986.1 - 2.6e-10 40.4 0.0 4e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Cell morphogenesis C-terminal WD40 PF00400.27 ETO31987.1 - 3.8e-50 166.0 26.0 1.7e-11 43.5 0.5 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO31987.1 - 1.3e-06 26.8 4.1 0.0029 15.8 0.3 4.8 2 2 2 4 4 4 3 Nucleoporin Nup120/160 WD40 PF00400.27 ETO31988.1 - 3.4e-59 194.7 23.8 8e-11 41.3 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO31988.1 - 5.9e-15 54.4 4.0 9.1e-05 20.7 0.1 5.7 1 1 3 6 6 6 6 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO31988.1 - 0.00071 18.4 11.9 0.76 8.4 1.3 4.3 1 1 1 3 3 3 3 Nup133 N terminal like SMC_N PF02463.14 ETO31989.1 - 0.095 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain MRP-S33 PF08293.6 ETO31991.1 - 0.021 14.7 1.8 0.37 10.7 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit S27 TPR_12 PF13424.1 ETO31993.1 - 1.7e-55 184.8 2.0 2.5e-22 78.5 0.0 2.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO31993.1 - 1.5e-22 79.0 3.7 1.8e-11 43.5 0.3 2.1 2 0 0 2 2 2 2 TPR repeat TPR_10 PF13374.1 ETO31993.1 - 8.4e-20 70.0 0.0 3.1e-07 30.1 0.0 3.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO31993.1 - 1.1e-17 62.3 9.6 0.0002 20.9 0.3 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO31993.1 - 1.2e-16 59.0 1.1 0.0011 18.5 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO31993.1 - 2.7e-14 52.0 16.9 8.1e-05 22.0 0.4 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO31993.1 - 4.2e-12 44.9 19.5 0.00012 21.5 0.6 4.7 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO31993.1 - 4.6e-11 42.0 2.7 0.0057 16.7 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO31993.1 - 2.6e-08 34.0 0.8 0.00019 21.7 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO31993.1 - 8.2e-07 29.5 0.2 0.016 15.8 0.0 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO31993.1 - 1.4e-06 28.4 0.0 0.48 11.2 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat PPR PF01535.15 ETO31993.1 - 8.9e-05 22.2 5.3 0.56 10.3 0.0 4.4 4 0 0 4 4 4 1 PPR repeat TPR_6 PF13174.1 ETO31993.1 - 0.00071 19.8 2.8 7.6 7.2 0.1 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.4 ETO31993.1 - 0.0015 18.5 1.9 0.039 13.8 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO31993.1 - 0.0015 17.6 1.2 0.4 9.9 0.0 3.8 4 0 0 4 4 4 1 SHNi-TPR Apc3 PF12895.2 ETO31993.1 - 0.004 17.2 2.3 1.9 8.6 0.3 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF2225 PF09986.4 ETO31993.1 - 0.011 15.1 1.3 0.39 10.1 0.9 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.13 ETO31993.1 - 0.022 14.6 4.9 11 6.0 0.0 3.9 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Ten1_2 PF15490.1 ETO31993.1 - 0.097 12.2 0.0 5.1 6.7 0.0 2.4 1 1 1 2 2 2 0 Telomere-capping, CST complex subunit DUF627 PF04781.7 ETO31993.1 - 0.22 11.1 1.3 1.5 8.4 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF627) Fis1_TPR_C PF14853.1 ETO31993.1 - 1.1 9.2 4.7 3.5 7.5 0.1 2.7 3 0 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.7 ETO31993.1 - 2 8.2 7.5 35 4.3 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.27 ETO31994.1 - 1.3e-45 151.7 6.0 3.4e-12 45.7 0.0 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO31994.1 - 4.2e-05 23.5 9.0 0.0078 16.3 0.2 5.6 6 0 0 6 6 6 1 Kelch motif PD40 PF07676.7 ETO31994.1 - 0.0011 18.5 0.0 36 4.1 0.0 4.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Kelch_3 PF13415.1 ETO31994.1 - 0.0046 17.0 2.7 2.4 8.4 0.0 4.2 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO31994.1 - 0.0052 16.7 0.1 0.91 9.5 0.4 3.8 3 0 0 3 3 3 1 Kelch motif PQQ_2 PF13360.1 ETO31994.1 - 0.015 14.7 0.2 0.078 12.4 0.1 2.1 1 1 1 2 2 2 0 PQQ-like domain Kelch_4 PF13418.1 ETO31994.1 - 0.079 12.7 0.4 4 7.2 0.0 3.5 3 0 0 3 3 3 0 Galactose oxidase, central domain Proteasome_A_N PF10584.4 ETO31994.1 - 0.49 9.7 6.7 18 4.7 0.0 4.6 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Kelch_1 PF01344.20 ETO31994.1 - 1.2 8.7 6.6 0.46 10.0 0.7 3.2 3 0 0 3 3 3 0 Kelch motif WD40 PF00400.27 ETO31995.1 - 1.3e-69 227.7 8.8 5.3e-12 45.1 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO31995.1 - 1.3e-14 54.3 0.2 0.00018 21.2 0.0 3.3 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO31995.1 - 9.8e-05 20.6 3.1 0.39 8.7 0.3 4.2 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO31995.1 - 0.00011 20.6 2.3 0.23 9.7 0.1 3.4 1 1 5 6 6 6 5 Cytochrome D1 heme domain Resistin PF06954.6 ETO31995.1 - 0.0091 16.2 0.0 16 5.8 0.1 3.8 3 1 1 4 4 4 1 Resistin PQQ PF01011.16 ETO31995.1 - 0.015 14.8 0.0 0.3 10.7 0.0 3.0 2 0 0 2 2 2 0 PQQ enzyme repeat DUF1652 PF07865.6 ETO31995.1 - 0.044 13.3 0.1 2 8.0 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1652) PD40 PF07676.7 ETO31995.1 - 0.074 12.7 9.6 42 3.9 0.1 5.6 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 ETO31995.1 - 4.1 6.8 9.5 11 5.4 0.1 4.2 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 ETO31996.1 - 2.3e-24 84.3 8.9 1.5e-06 27.8 0.2 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat DUF1823 PF08853.6 ETO31997.1 - 0.013 15.2 0.7 0.031 14.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1823) DOCK-C2 PF14429.1 ETO31998.1 - 1.9e-18 66.7 1.7 2.3e-18 66.5 0.2 2.0 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins MOR2-PAG1_C PF14225.1 ETO32000.1 - 3.2e-11 43.4 2.6 4.5e-08 33.1 0.0 4.0 5 0 0 5 5 5 2 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 ETO32000.1 - 0.00025 18.7 0.3 0.11 10.0 0.0 2.1 2 0 0 2 2 2 2 Cell morphogenesis central region RhoGEF PF00621.15 ETO32003.1 - 0.0086 15.9 0.4 0.0097 15.7 0.3 1.2 1 0 0 1 1 1 1 RhoGEF domain DUF3654 PF12376.3 ETO32004.1 - 0.068 12.9 0.1 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3654) BC10 PF06726.7 ETO32005.1 - 0.84 9.6 0.0 0.84 9.6 0.0 2.3 2 0 0 2 2 2 0 Bladder cancer-related protein BC10 Rifin_STEVOR PF02009.11 ETO32005.1 - 1.1 8.7 5.7 2.1 7.8 4.0 1.5 1 1 0 1 1 1 0 Rifin/stevor family Vma12 PF11712.3 ETO32006.1 - 0.0034 17.0 0.0 0.005 16.5 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF912 PF06024.7 ETO32006.1 - 0.013 15.5 4.8 0.013 15.5 2.3 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Synaptobrevin PF00957.16 ETO32006.1 - 0.15 11.7 7.6 0.036 13.6 2.2 2.2 2 0 0 2 2 2 0 Synaptobrevin DUF3753 PF12575.3 ETO32006.1 - 0.18 11.6 10.3 0.049 13.4 5.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) Rifin_STEVOR PF02009.11 ETO32006.1 - 0.41 10.2 12.8 0.71 9.4 8.9 1.7 1 1 0 1 1 1 0 Rifin/stevor family TMEM154 PF15102.1 ETO32006.1 - 0.79 9.4 6.7 1.1 8.9 4.7 1.4 1 1 0 1 1 1 0 TMEM154 protein family Shisa PF13908.1 ETO32006.1 - 1.8 8.6 4.0 1.1 9.3 0.8 2.0 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator RasGEF_N PF00618.15 ETO32007.1 - 0.91 9.6 7.1 3 7.9 3.6 2.8 2 1 0 2 2 2 0 RasGEF N-terminal motif L27_1 PF09058.5 ETO32008.1 - 0.066 13.1 0.8 0.15 11.9 0.1 1.9 2 0 0 2 2 2 0 L27_1 Mpv17_PMP22 PF04117.7 ETO32009.1 - 0.089 12.4 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 Mpv17 / PMP22 family GatB_Yqey PF02637.13 ETO32010.1 - 0.022 14.4 0.0 0.053 13.2 0.0 1.6 1 0 0 1 1 1 0 GatB domain Folliculin PF11704.3 ETO32010.1 - 0.57 9.7 8.2 0.18 11.3 0.5 3.0 3 0 0 3 3 3 0 Vesicle coat protein involved in Golgi to plasma membrane transport Ank_2 PF12796.2 ETO32012.1 - 0.086 13.1 0.3 0.33 11.3 0.2 2.1 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) UPF0370 PF13980.1 ETO32014.1 - 0.2 11.5 0.0 0.2 11.5 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) Spt5_N PF11942.3 ETO32014.1 - 3.7 8.2 8.6 3.7 8.2 0.8 2.6 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal DUF3020 PF11223.3 ETO32014.1 - 5.7 7.4 7.6 2.6 8.5 0.9 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3020) zf-H2C2_2 PF13465.1 ETO32015.1 - 5.7e-11 42.1 26.4 2.3e-06 27.5 1.5 4.9 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.21 ETO32015.1 - 3.2e-07 30.2 32.7 0.0025 18.0 1.8 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETO32015.1 - 0.01 16.1 38.0 0.16 12.3 2.1 5.6 6 0 0 6 6 6 0 C2H2-type zinc finger Thg1C PF14413.1 ETO32015.1 - 0.041 13.5 1.2 0.082 12.5 0.9 1.5 1 0 0 1 1 1 0 Thg1 C terminal domain zf-CHCC PF10276.4 ETO32015.1 - 0.075 12.8 2.5 8.9 6.2 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger domain zf-BED PF02892.10 ETO32015.1 - 1.5 8.6 24.1 0.94 9.2 3.6 4.3 2 1 2 4 4 4 0 BED zinc finger Zn_Tnp_IS1595 PF12760.2 ETO32015.1 - 1.6 8.5 12.3 3.7 7.4 3.0 3.5 3 0 0 3 3 3 0 Transposase zinc-ribbon domain HypA PF01155.14 ETO32015.1 - 1.8 8.2 7.5 61 3.3 3.3 2.8 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-Di19 PF05605.7 ETO32015.1 - 3.3 7.9 15.1 0.76 9.9 0.5 3.6 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding DUF4379 PF14311.1 ETO32015.1 - 6.1 6.7 11.4 2.1 8.1 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4379) PepX_N PF09168.5 ETO32016.1 - 0.051 13.8 0.1 0.051 13.8 0.0 1.5 2 0 0 2 2 2 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal CFIA_Pcf11 PF11526.3 ETO32016.1 - 1.9 8.6 4.6 2.1 8.5 0.0 2.3 1 1 1 2 2 2 0 Subunit of cleavage factor IA Pcf11 Kelch_5 PF13854.1 ETO32017.1 - 0.0052 16.7 6.7 0.13 12.3 1.7 2.9 3 0 0 3 3 3 2 Kelch motif DUF2175 PF09943.4 ETO32017.1 - 0.049 13.6 0.9 1.3 9.0 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Kelch_6 PF13964.1 ETO32017.1 - 0.051 13.7 4.2 10 6.5 1.2 3.3 3 0 0 3 3 3 0 Kelch motif Ovate PF04844.8 ETO32017.1 - 0.16 11.7 0.5 0.92 9.3 0.0 2.3 2 0 0 2 2 2 0 Transcriptional repressor, ovate Kelch_2 PF07646.10 ETO32017.1 - 0.23 11.2 2.0 3.4 7.5 0.2 3.0 3 0 0 3 3 3 0 Kelch motif WD40 PF00400.27 ETO32018.1 - 1.1e-79 259.6 10.3 1.3e-12 47.0 0.0 7.0 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO32018.1 - 4.7e-12 46.0 0.4 1.1e-05 25.2 0.0 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO32018.1 - 6.5e-09 34.4 4.1 0.12 10.5 0.0 4.5 1 1 4 5 5 5 3 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO32018.1 - 4.9e-06 26.0 1.1 0.16 11.2 0.0 3.7 1 1 3 4 4 4 2 Domain of unknown function (DUF4221) Nucleoporin_N PF08801.6 ETO32018.1 - 5.6e-06 25.3 8.3 0.2 10.3 0.3 4.7 1 1 2 4 4 4 3 Nup133 N terminal like Resistin PF06954.6 ETO32018.1 - 0.0001 22.4 1.3 4.3 7.6 0.0 4.3 1 1 2 4 4 4 1 Resistin PQQ_2 PF13360.1 ETO32018.1 - 0.00031 20.2 0.1 0.17 11.2 0.0 2.3 1 1 1 2 2 2 2 PQQ-like domain PD40 PF07676.7 ETO32018.1 - 0.00076 19.0 6.7 9.2 6.0 0.0 5.6 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 ETO32018.1 - 0.0019 17.3 0.5 0.033 13.2 0.1 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF1258) Cytochrom_D1 PF02239.11 ETO32018.1 - 0.0038 15.5 0.6 0.45 8.7 0.1 2.3 1 1 0 2 2 2 2 Cytochrome D1 heme domain MRJP PF03022.11 ETO32018.1 - 0.046 12.9 2.2 2.2 7.4 0.0 2.9 2 1 1 3 3 3 0 Major royal jelly protein CTX_RstB PF07459.6 ETO32018.1 - 0.06 13.2 0.3 0.17 11.7 0.1 1.9 2 0 0 2 2 2 0 CTX phage RstB protein Proteasome_A_N PF10584.4 ETO32018.1 - 0.066 12.5 5.6 3.2 7.1 0.0 4.6 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature LRR_5 PF13306.1 ETO32018.1 - 0.11 12.2 0.1 18 5.0 0.0 2.3 2 0 0 2 2 2 0 Leucine rich repeats (6 copies) WD40 PF00400.27 ETO32020.1 - 3.9e-05 23.3 0.5 0.27 11.1 0.1 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat Rtt106 PF08512.7 ETO32020.1 - 0.015 15.3 1.5 0.031 14.2 1.0 1.6 1 0 0 1 1 1 0 Histone chaperone Rttp106-like Nup160 PF11715.3 ETO32020.1 - 0.026 12.6 0.0 0.033 12.3 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DUF1724 PF08350.5 ETO32020.1 - 0.062 12.8 0.3 0.15 11.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1724) WD40 PF00400.27 ETO32021.1 - 4e-50 165.9 8.5 2.5e-12 46.1 0.2 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat RicinB_lectin_2 PF14200.1 ETO32022.1 - 1.9e-21 76.4 6.8 2e-13 50.6 0.6 2.6 1 1 2 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 ETO32022.1 - 4.4e-06 26.7 10.7 0.00044 20.2 1.8 1.8 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain FGF PF00167.13 ETO32022.1 - 0.0057 16.4 0.1 0.058 13.1 0.0 2.2 1 1 1 2 2 2 1 Fibroblast growth factor Agglutinin PF07468.6 ETO32022.1 - 0.093 12.7 2.5 0.081 12.9 0.8 1.6 2 0 0 2 2 2 0 Agglutinin Hemopexin PF00045.14 ETO32024.1 - 4.7e-05 23.0 5.8 4.7e-05 23.0 4.0 2.8 3 1 0 3 3 3 1 Hemopexin PT PF04886.7 ETO32024.1 - 0.0021 17.3 9.8 0.0021 17.3 6.8 1.7 2 0 0 2 2 2 1 PT repeat WD40 PF00400.27 ETO32025.1 - 1.2e-05 24.9 8.7 0.012 15.4 0.0 3.9 5 0 0 5 5 5 2 WD domain, G-beta repeat SDA1 PF05285.7 ETO32025.1 - 8 5.6 37.6 0.72 9.0 19.7 2.2 2 0 0 2 2 2 0 SDA1 CagX PF03524.10 ETO32026.1 - 0.017 14.3 3.2 0.023 13.9 2.2 1.2 1 0 0 1 1 1 0 Conjugal transfer protein Aconitase PF00330.15 ETO32026.1 - 0.049 12.1 1.8 0.056 11.9 1.2 1.0 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) DUF718 PF05336.8 ETO32026.1 - 0.086 12.6 1.6 0.2 11.4 1.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF718) Tfb4 PF03850.9 ETO32026.1 - 0.82 8.8 3.8 1 8.5 2.6 1.2 1 0 0 1 1 1 0 Transcription factor Tfb4 PP_M1 PF03012.9 ETO32026.1 - 2.1 7.6 9.6 3.3 6.9 6.6 1.4 1 1 0 1 1 1 0 Phosphoprotein DDHD PF02862.12 ETO32026.1 - 2.2 8.0 5.9 2.6 7.7 4.1 1.1 1 0 0 1 1 1 0 DDHD domain DUF3464 PF11947.3 ETO32026.1 - 2.5 7.5 6.2 3 7.2 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) RHD PF00554.17 ETO32026.1 - 5.2 6.7 9.3 8.4 6.0 6.5 1.5 1 1 0 1 1 1 0 Rel homology domain (RHD) Neur_chan_memb PF02932.11 ETO32026.1 - 5.4 6.8 6.7 5.9 6.7 4.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region N6_N4_Mtase PF01555.13 ETO32026.1 - 9.2 5.6 11.5 13 5.2 7.9 1.2 1 0 0 1 1 1 0 DNA methylase Bd3614_N PF14442.1 ETO32029.1 - 0.24 11.3 2.9 0.4 10.6 2.0 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal Herpes_UL32 PF06070.6 ETO32029.1 - 0.27 9.6 1.7 0.36 9.2 1.2 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 TFIIF_alpha PF05793.7 ETO32029.1 - 0.99 7.7 11.5 1.3 7.3 8.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RNase_H PF00075.19 ETO32030.1 - 6.8e-12 45.8 0.0 1.4e-11 44.8 0.0 1.5 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.1 ETO32030.1 - 0.00055 19.6 0.1 0.0086 15.8 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase-like G-alpha PF00503.15 ETO32033.1 - 3.4e-86 289.3 3.4 4.4e-86 289.0 2.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO32033.1 - 1.1e-10 41.0 1.1 1.6e-07 30.6 0.1 3.0 2 2 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 ETO32033.1 - 2.5e-05 24.7 0.2 0.13 12.7 0.0 2.7 1 1 1 2 2 2 2 Miro-like protein AAA_33 PF13671.1 ETO32033.1 - 0.0025 17.6 0.0 0.015 15.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 ETO32033.1 - 0.0033 17.3 0.0 2.8 7.9 0.0 2.5 2 1 0 2 2 2 2 50S ribosome-binding GTPase Siva PF05458.7 ETO32033.1 - 0.0047 16.5 0.0 0.052 13.1 0.0 2.1 2 0 0 2 2 2 1 Cd27 binding protein (Siva) SMC_N PF02463.14 ETO32033.1 - 0.0086 15.3 0.1 0.015 14.5 0.1 1.5 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 ETO32033.1 - 0.015 14.8 0.0 0.034 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 ETO32033.1 - 0.027 14.7 0.3 0.053 13.8 0.2 1.5 1 1 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.13 ETO32033.1 - 0.041 13.3 0.0 0.074 12.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Gtr1_RagA PF04670.7 ETO32033.1 - 0.046 12.8 4.2 1.1 8.3 0.0 2.8 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region Mg_chelatase PF01078.16 ETO32033.1 - 0.046 12.8 0.0 0.099 11.7 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 ETO32033.1 - 0.093 13.5 0.4 0.31 11.8 0.3 1.9 1 1 0 1 1 1 0 AAA domain SBDS PF01172.13 ETO32034.1 - 7.6e-18 64.0 0.0 9.7e-18 63.7 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein AIG1 PF04548.11 ETO32035.1 - 3.4e-05 23.0 0.3 0.00023 20.3 0.1 2.4 1 1 0 1 1 1 1 AIG1 family T2SE PF00437.15 ETO32035.1 - 0.00071 18.5 0.5 0.0022 16.9 0.0 2.0 2 1 0 2 2 2 1 Type II/IV secretion system protein IncA PF04156.9 ETO32035.1 - 0.003 17.1 7.5 0.0083 15.7 0.0 3.0 3 0 0 3 3 3 1 IncA protein ABC_tran PF00005.22 ETO32035.1 - 0.006 16.8 0.7 0.017 15.3 0.1 2.2 2 0 0 2 2 2 1 ABC transporter DUF4600 PF15372.1 ETO32035.1 - 0.021 15.0 0.1 0.021 15.0 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4600) DBI_PRT PF02277.12 ETO32035.1 - 0.046 12.8 0.3 0.19 10.7 0.0 1.9 2 0 0 2 2 2 0 Phosphoribosyltransferase AAA PF00004.24 ETO32035.1 - 0.049 13.8 0.0 3.8 7.7 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Med9 PF07544.8 ETO32035.1 - 0.13 11.9 6.7 1.6 8.5 0.6 2.9 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Tn7_Tnp_TnsA_C PF08721.6 ETO32036.1 - 0.012 15.5 0.2 0.27 11.2 0.0 3.5 2 1 0 2 2 2 0 TnsA endonuclease C terminal UPF0118 PF01594.11 ETO32036.1 - 0.17 10.8 0.1 0.3 10.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF20 ABC_tran PF00005.22 ETO32037.1 - 6.4e-08 32.9 0.1 6.4e-08 32.9 0.1 1.9 2 1 0 2 2 2 1 ABC transporter DUF258 PF03193.11 ETO32037.1 - 0.0085 15.2 0.6 0.013 14.6 0.3 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AFT PF08731.6 ETO32037.1 - 0.076 13.2 4.7 0.11 12.6 3.2 1.2 1 0 0 1 1 1 0 Transcription factor AFT AAA_29 PF13555.1 ETO32037.1 - 0.078 12.5 0.3 0.2 11.2 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain EBV-NA3 PF05009.7 ETO32038.1 - 0.87 8.7 5.0 1.7 7.7 1.1 2.2 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Nop14 PF04147.7 ETO32038.1 - 3.3 5.5 17.6 1.4 6.7 1.7 2.2 2 0 0 2 2 2 0 Nop14-like family LRR_1 PF00560.28 ETO32039.1 - 3.7e-09 35.3 27.1 0.053 13.5 0.0 10.3 9 0 0 9 9 9 4 Leucine Rich Repeat LRR_4 PF12799.2 ETO32039.1 - 4.8e-09 35.6 42.0 0.00085 18.8 2.8 7.9 5 3 5 10 10 10 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO32039.1 - 2e-05 24.2 17.5 0.00048 19.8 3.6 5.5 5 1 0 6 6 6 2 Leucine rich repeat LRR_6 PF13516.1 ETO32039.1 - 0.0018 18.1 17.1 1.4 9.2 0.2 6.6 6 0 0 6 6 6 3 Leucine Rich repeat LRR_7 PF13504.1 ETO32039.1 - 0.055 13.6 17.0 10 6.8 0.1 7.9 7 0 0 7 7 7 0 Leucine rich repeat WD40 PF00400.27 ETO32040.1 - 4.2e-60 197.6 32.5 2.4e-11 43.0 0.1 6.8 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO32040.1 - 2.6e-08 32.4 3.3 0.0065 14.6 0.2 4.6 2 2 3 5 5 5 3 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO32040.1 - 0.044 13.9 13.6 3.6 7.9 0.0 5.4 5 1 1 6 6 6 0 Kelch motif DUF3502 PF12010.3 ETO32042.1 - 0.071 13.0 0.4 0.11 12.5 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3502) PsbL PF02419.12 ETO32043.1 - 0.089 12.2 0.0 0.089 12.2 0.0 2.3 2 0 0 2 2 2 0 PsbL protein zf-C2HC_2 PF13913.1 ETO32044.1 - 0.095 12.3 0.2 0.095 12.3 0.1 1.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2 PF00096.21 ETO32044.1 - 0.28 11.5 0.4 0.28 11.5 0.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Bystin PF05291.6 ETO32046.1 - 2.3e-85 286.1 5.4 1.2e-54 185.3 0.9 2.5 2 0 0 2 2 2 2 Bystin Trypan_PARP PF05887.6 ETO32047.1 - 0.35 10.6 10.7 0.72 9.6 7.4 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) EcKinase PF02958.15 ETO32048.1 - 0.00077 18.6 0.1 0.0016 17.6 0.0 1.5 1 1 0 1 1 1 1 Ecdysteroid kinase DUF3025 PF11227.3 ETO32048.1 - 0.0036 16.8 0.0 0.0056 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3025) OSCP PF00213.13 ETO32048.1 - 0.21 11.4 4.6 0.086 12.7 0.3 2.1 1 1 1 2 2 2 0 ATP synthase delta (OSCP) subunit His_Phos_2 PF00328.17 ETO32049.1 - 9.8e-12 44.8 0.0 1.3e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF1295 PF06966.7 ETO32050.1 - 1.9e-31 109.1 17.1 1.9e-31 109.1 11.8 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 ETO32050.1 - 0.009 16.1 1.1 0.025 14.7 0.0 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 ETO32050.1 - 0.015 15.3 3.9 0.017 15.2 0.1 2.8 2 1 1 3 3 3 0 Phospholipid methyltransferase Kinesin PF00225.18 ETO32051.1 - 3.2e-93 312.1 0.4 1.7e-50 171.6 0.5 3.3 2 2 1 3 3 3 2 Kinesin motor domain ERM PF00769.14 ETO32051.1 - 0.0018 17.8 24.8 0.0018 17.8 17.2 3.0 2 1 1 3 3 3 1 Ezrin/radixin/moesin family PIG-P PF08510.7 ETO32051.1 - 0.02 14.4 1.6 1.5 8.4 0.0 2.7 2 0 0 2 2 2 0 PIG-P DUF4140 PF13600.1 ETO32051.1 - 1.7 9.1 18.6 0.26 11.7 0.4 4.3 4 0 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) DUF3372 PF11852.3 ETO32053.1 - 5.2e-05 22.4 3.2 0.00011 21.4 2.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3372) RCC1 PF00415.13 ETO32053.1 - 0.0032 17.6 0.0 3.4 7.9 0.0 2.4 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat DUF2924 PF11149.3 ETO32055.1 - 1.9 8.5 6.9 3.8 7.5 0.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2924) BTB_2 PF02214.17 ETO32057.1 - 1.2e-05 25.4 0.3 0.00014 22.0 0.1 2.3 2 0 0 2 2 2 1 BTB/POZ domain Peptidase_C14 PF00656.17 ETO32058.1 - 2.2e-12 47.2 1.3 1e-11 44.9 0.8 2.0 1 1 0 1 1 1 1 Caspase domain DUF4268 PF14088.1 ETO32058.1 - 0.05 13.2 2.9 1.3 8.6 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4268) Kelch_2 PF07646.10 ETO32058.1 - 0.23 11.2 0.9 12 5.8 0.0 3.3 3 0 0 3 3 3 0 Kelch motif Muted PF14942.1 ETO32059.1 - 0.028 14.3 1.9 0.05 13.4 1.3 1.3 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Pox_A12 PF04651.8 ETO32059.1 - 0.47 10.5 6.6 2.1 8.4 0.7 2.3 2 0 0 2 2 2 0 Poxvirus A12 protein GrpE PF01025.14 ETO32059.1 - 0.84 9.1 7.9 1.3 8.4 5.5 1.2 1 0 0 1 1 1 0 GrpE CENP-Q PF13094.1 ETO32060.1 - 0.0065 16.5 11.5 0.0065 16.5 8.0 3.2 2 1 2 4 4 4 1 CENP-Q, a CENPA-CAD centromere complex subunit COG5 PF10392.4 ETO32060.1 - 0.01 15.8 5.0 0.01 15.8 3.5 3.9 3 1 1 4 4 4 1 Golgi transport complex subunit 5 DUF904 PF06005.7 ETO32060.1 - 7.8 6.8 46.3 0.85 9.9 6.4 4.8 2 2 2 4 4 4 0 Protein of unknown function (DUF904) DUF3671 PF12420.3 ETO32063.1 - 0.071 13.0 0.5 0.071 13.0 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function Serinc PF03348.10 ETO32064.1 - 0.14 10.8 2.6 0.15 10.7 1.8 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Peptidase_M4 PF01447.13 ETO32064.1 - 0.22 11.6 4.3 0.26 11.3 3.0 1.0 1 0 0 1 1 1 0 Thermolysin metallopeptidase, catalytic domain DUF4238 PF14022.1 ETO32064.1 - 0.58 9.3 8.0 0.62 9.2 5.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) Herpes_env PF01673.13 ETO32064.1 - 0.63 8.5 7.7 0.72 8.3 5.3 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein PIN_2 PF10130.4 ETO32064.1 - 0.67 9.9 6.9 0.52 10.3 4.0 1.4 1 1 0 1 1 1 0 PIN domain Adeno_VII PF03228.9 ETO32064.1 - 4.6 7.8 10.2 5.8 7.5 7.1 1.3 1 0 0 1 1 1 0 Adenoviral core protein VII L_lac_phage_MSP PF06488.6 ETO32066.1 - 0.012 14.7 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major structural protein RST PF12174.3 ETO32066.1 - 0.2 11.4 1.6 0.75 9.6 0.2 2.2 1 1 1 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain FlaC_arch PF05377.6 ETO32067.1 - 0.069 13.0 0.9 0.069 13.0 0.6 3.4 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) AAA_13 PF13166.1 ETO32067.1 - 0.75 8.1 28.2 0.96 7.8 19.5 1.1 1 0 0 1 1 1 0 AAA domain KID PF02524.9 ETO32067.1 - 3.1 8.3 8.3 4.8 7.7 0.3 4.8 4 0 0 4 4 4 0 KID repeat Pox_A_type_inc PF04508.7 ETO32067.1 - 5.3 7.0 13.7 2.9 7.9 0.2 4.5 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat MvaI_BcnI PF15515.1 ETO32069.1 - 0.74 9.7 3.8 2.2 8.2 0.6 2.0 1 1 1 2 2 2 0 MvaI/BcnI restriction endonuclease family FGGY_C PF02782.11 ETO32070.1 - 3.4e-41 141.0 0.0 5e-41 140.5 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 ETO32070.1 - 1.9e-11 43.7 0.0 3.8e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain UCH PF00443.24 ETO32071.1 - 2.6e-29 102.1 1.6 6.1e-29 100.9 1.1 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO32071.1 - 2.3e-05 23.9 2.5 2.3e-05 23.9 1.8 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase GAGA_bind PF06217.7 ETO32071.1 - 0.51 10.2 12.7 0.81 9.5 7.3 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family Nucleo_P87 PF07267.6 ETO32071.1 - 0.71 8.4 11.6 1.5 7.4 8.0 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 zf-4CXXC_R1 PF10497.4 ETO32073.1 - 0.0037 17.3 17.8 0.0046 17.0 4.1 2.5 2 1 0 2 2 2 2 Zinc-finger domain of monoamine-oxidase A repressor R1 Folate_carrier PF01770.13 ETO32074.1 - 0.049 12.1 0.4 0.068 11.6 0.3 1.3 1 0 0 1 1 1 0 Reduced folate carrier zf-TFIIIC PF12660.2 ETO32074.1 - 3.8 7.4 12.0 2.3 8.1 0.1 3.3 3 1 0 3 3 3 0 Putative zinc-finger of transcription factor IIIC complex Metallophos PF00149.23 ETO32075.1 - 2.8e-13 49.7 1.3 7.1e-08 32.0 0.1 2.4 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase AOX PF01786.12 ETO32075.1 - 0.11 11.9 0.3 1.5 8.1 0.4 2.1 2 0 0 2 2 2 0 Alternative oxidase DUF1218 PF06749.7 ETO32075.1 - 0.21 12.0 3.2 3.3 8.2 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) CH PF00307.26 ETO32076.1 - 1.4e-25 89.4 1.3 2.7e-10 40.2 0.0 6.0 6 0 0 6 6 6 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 ETO32076.1 - 0.00072 19.1 0.0 0.034 13.8 0.0 2.8 2 0 0 2 2 2 1 CAMSAP CH domain ENOD93 PF03386.9 ETO32076.1 - 0.19 11.4 0.5 0.44 10.3 0.0 1.8 2 0 0 2 2 2 0 Early nodulin 93 ENOD93 protein Pkinase PF00069.20 ETO32077.1 - 9.7e-47 159.2 0.0 1.2e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO32077.1 - 2.9e-16 59.3 0.0 6e-16 58.3 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Alpha-mann_mid PF09261.6 ETO32078.1 - 4.1e-15 55.7 0.1 8.8e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Glyco_hydro_38 PF01074.17 ETO32078.1 - 6.8e-11 41.9 0.1 1e-10 41.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain APG17 PF04108.7 ETO32079.1 - 7.1e-06 25.0 0.0 7.1e-06 25.0 0.0 2.2 3 0 0 3 3 3 1 Autophagy protein Apg17 fn3 PF00041.16 ETO32080.1 - 5.2e-12 45.7 3.2 1.6e-07 31.3 0.5 3.0 2 1 1 3 3 3 2 Fibronectin type III domain Interfer-bind PF09294.5 ETO32080.1 - 0.42 10.6 6.2 1.5 8.9 0.1 3.2 4 0 0 4 4 4 0 Interferon-alpha/beta receptor, fibronectin type III LOH1CR12 PF10158.4 ETO32081.1 - 0.033 13.9 1.3 0.081 12.7 0.9 1.6 1 0 0 1 1 1 0 Tumour suppressor protein Syntaxin_2 PF14523.1 ETO32081.1 - 0.051 13.6 0.9 0.13 12.3 0.6 1.6 1 0 0 1 1 1 0 Syntaxin-like protein NPV_P10 PF05531.7 ETO32081.1 - 0.11 12.7 0.5 0.11 12.7 0.3 2.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1398 PF07166.6 ETO32081.1 - 0.19 11.6 0.2 0.19 11.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1398) DUF2205 PF10224.4 ETO32081.1 - 0.41 10.2 4.4 2.4 7.8 2.8 2.3 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF4200 PF13863.1 ETO32081.1 - 0.66 9.9 13.7 1 9.2 7.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) bZIP_1 PF00170.16 ETO32081.1 - 0.72 9.8 4.1 22 5.0 0.6 2.9 2 0 0 2 2 2 0 bZIP transcription factor DUF4140 PF13600.1 ETO32081.1 - 0.87 10.0 4.2 1.1 9.6 0.3 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) SlyX PF04102.7 ETO32081.1 - 1.9 8.8 5.3 1.7 9.0 2.3 2.0 2 0 0 2 2 2 0 SlyX DUF4094 PF13334.1 ETO32081.1 - 2.6 8.4 6.8 2.8 8.4 0.1 3.5 2 1 2 4 4 4 0 Domain of unknown function (DUF4094) FlaC_arch PF05377.6 ETO32081.1 - 6.1 6.8 9.9 5.2 7.0 2.2 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.10 ETO32081.1 - 6.9 6.2 9.6 2.4 7.6 2.1 2.7 1 1 1 2 2 2 0 Septum formation initiator WD40 PF00400.27 ETO32083.1 - 1.8e-175 563.4 51.1 4.3e-13 48.5 0.2 14.5 14 0 0 14 14 14 14 WD domain, G-beta repeat Gmad1 PF10647.4 ETO32083.1 - 7.7e-13 48.4 0.2 0.011 15.0 0.0 6.0 2 2 4 6 6 6 3 Lipoprotein LpqB beta-propeller domain NACHT PF05729.7 ETO32083.1 - 7.5e-09 35.4 0.0 1.5e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Pentapeptide_4 PF13599.1 ETO32083.1 - 0.00093 18.9 0.2 0.0026 17.5 0.1 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) PD40 PF07676.7 ETO32083.1 - 0.001 18.6 23.1 6 6.6 0.3 10.2 11 0 0 11 11 11 2 WD40-like Beta Propeller Repeat Pentapeptide PF00805.17 ETO32083.1 - 0.0028 16.8 0.4 0.0055 15.9 0.3 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) DDE_3 PF13358.1 ETO32084.1 - 3.9e-27 94.7 0.1 3.9e-27 94.7 0.1 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 ETO32084.1 - 1.6e-12 47.2 6.1 1.6e-12 47.2 4.2 2.3 2 0 0 2 2 2 1 Transposase ATG27 PF09451.5 ETO32085.1 - 0.00016 21.0 1.6 0.00022 20.5 0.7 1.5 1 1 0 1 1 1 1 Autophagy-related protein 27 MARVEL PF01284.18 ETO32085.1 - 0.25 11.1 2.6 0.71 9.6 0.2 2.4 2 1 1 3 3 3 0 Membrane-associating domain Orthoreo_P10 PF07204.6 ETO32085.1 - 0.37 10.5 4.6 0.14 11.9 0.9 2.1 2 1 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 UCH PF00443.24 ETO32088.1 - 1.7e-14 53.5 0.1 3.6e-14 52.5 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Kelch_5 PF13854.1 ETO32089.1 - 1.5e-05 24.8 0.4 0.88 9.6 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO32089.1 - 1.8e-05 24.6 7.5 0.0087 16.1 0.0 4.3 4 1 1 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO32089.1 - 0.00072 19.0 3.0 0.11 12.0 0.2 4.5 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.1 ETO32089.1 - 0.0015 18.6 3.1 0.044 13.9 0.0 4.1 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO32089.1 - 0.022 14.5 1.2 4.2 7.3 0.0 4.2 5 0 0 5 5 5 0 Kelch motif Kelch_4 PF13418.1 ETO32089.1 - 0.03 14.0 5.8 0.11 12.2 0.0 4.2 5 1 1 6 6 6 0 Galactose oxidase, central domain Apc13p PF05839.6 ETO32089.1 - 0.14 12.1 0.1 0.14 12.1 0.1 1.9 2 0 0 2 2 2 0 Apc13p protein EF-hand_1 PF00036.27 ETO32090.1 - 7.4e-23 78.0 9.1 1.4e-08 33.4 0.2 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 ETO32090.1 - 2.4e-22 76.7 4.9 7.6e-09 34.7 0.1 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 ETO32090.1 - 2.1e-20 72.5 5.1 7.7e-10 38.7 0.3 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 ETO32090.1 - 8.1e-17 60.5 9.2 1.2e-06 27.9 0.1 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.1 ETO32090.1 - 9.6e-14 51.0 0.3 4.7e-07 29.6 0.0 2.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 ETO32090.1 - 1.1e-10 40.3 12.5 1.3e-05 24.3 0.2 4.3 5 0 0 5 5 5 3 EF hand EF-hand_4 PF12763.2 ETO32090.1 - 0.00037 20.2 2.1 0.75 9.5 1.1 2.5 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand TRCF PF03461.10 ETO32090.1 - 0.0072 16.2 0.6 0.28 11.1 0.1 2.3 1 1 1 2 2 2 1 TRCF domain Toprim_2 PF13155.1 ETO32090.1 - 0.014 15.7 4.4 2.8 8.3 0.4 2.9 1 1 2 3 3 3 0 Toprim-like Toprim PF01751.17 ETO32090.1 - 0.057 13.3 0.3 0.36 10.8 0.2 2.3 1 1 0 1 1 1 0 Toprim domain PH PF00169.24 ETO32091.1 - 4.1e-05 23.7 13.3 0.013 15.7 2.8 3.6 3 1 0 3 3 3 2 PH domain NAF PF03822.9 ETO32092.1 - 0.00024 20.7 0.0 0.00096 18.8 0.0 2.0 1 0 0 1 1 1 1 NAF domain AMPKBI PF04739.10 ETO32092.1 - 1.5 8.7 10.2 0.082 12.7 0.6 2.4 2 0 0 2 2 2 0 5'-AMP-activated protein kinase beta subunit, interation domain Daxx PF03344.10 ETO32093.1 - 0.0084 14.6 26.9 0.011 14.2 18.7 1.1 1 0 0 1 1 1 1 Daxx Family SDA1 PF05285.7 ETO32093.1 - 0.093 11.9 21.3 0.13 11.5 14.8 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 ETO32093.1 - 0.14 10.0 24.0 0.2 9.5 16.6 1.2 1 0 0 1 1 1 0 Nop14-like family IpaD PF06511.6 ETO32093.1 - 0.28 10.1 4.3 0.41 9.5 3.0 1.1 1 0 0 1 1 1 0 Invasion plasmid antigen IpaD BSP_II PF05432.6 ETO32093.1 - 0.82 8.8 33.3 1.9 7.7 20.4 2.1 1 1 1 2 2 2 0 Bone sialoprotein II (BSP-II) Trypan_PARP PF05887.6 ETO32093.1 - 2.1 8.1 19.5 0.37 10.5 9.7 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF3915 PF13054.1 ETO32093.1 - 4.1 7.3 6.5 2.4 8.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Kinesin PF00225.18 ETO32094.1 - 0.00024 19.9 1.6 0.00062 18.5 1.1 1.7 1 0 0 1 1 1 1 Kinesin motor domain PMR5N PF14416.1 ETO32094.1 - 1.4 8.9 5.2 1 9.4 0.3 2.5 2 0 0 2 2 2 0 PMR5 N terminal Domain Gti1_Pac2 PF09729.4 ETO32096.1 - 0.025 14.4 0.3 0.15 11.9 0.2 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family YopE_N PF09020.5 ETO32096.1 - 8.1 6.5 8.5 29 4.7 2.3 2.5 2 0 0 2 2 2 0 YopE, N terminal DUF2884 PF11101.3 ETO32098.1 - 0.017 14.4 0.4 0.027 13.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) DUF3699 PF12480.3 ETO32100.1 - 0.079 12.6 0.4 2.5 7.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3699) DUF3948 PF13134.1 ETO32100.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3948) PDEase_I PF00233.14 ETO32101.1 - 1.3e-32 113.4 0.0 4.7e-24 85.4 0.0 2.0 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Pex14_N PF04695.8 ETO32101.1 - 0.043 13.8 0.2 0.06 13.3 0.2 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Trypan_PARP PF05887.6 ETO32101.1 - 1.1 9.0 6.2 1.6 8.4 4.3 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) LMBR1 PF04791.11 ETO32102.1 - 3.7e-10 38.9 8.7 4.4e-10 38.7 6.0 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein WD40 PF00400.27 ETO32103.1 - 7.3e-05 22.4 0.0 0.0002 21.1 0.0 1.8 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF2407 PF10302.4 ETO32103.1 - 0.058 13.5 0.2 0.42 10.8 0.2 2.1 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ribosomal_L2_C PF03947.13 ETO32104.1 - 1.6e-42 144.3 4.0 2.3e-42 143.8 2.8 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain LMBR1 PF04791.11 ETO32105.1 - 0.00031 19.4 0.0 0.00036 19.2 0.0 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein AA_permease_C PF13906.1 ETO32105.1 - 0.015 15.1 3.1 0.032 14.1 2.1 1.5 1 0 0 1 1 1 0 C-terminus of AA_permease 2TM PF13239.1 ETO32105.1 - 0.28 11.2 2.4 0.48 10.5 0.1 2.2 2 0 0 2 2 2 0 2TM domain BAAT_C PF08840.6 ETO32108.1 - 0.047 13.3 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal TMEM240 PF15207.1 ETO32108.1 - 0.068 12.7 1.3 0.092 12.3 0.2 1.7 2 0 0 2 2 2 0 TMEM240 family PNK3P PF08645.6 ETO32108.1 - 0.19 11.1 2.1 0.36 10.2 1.4 1.5 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase Lipase_GDSL_2 PF13472.1 ETO32109.1 - 5.5e-06 26.6 0.0 7.3e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 ETO32109.1 - 8.8e-05 22.4 0.2 0.00012 21.9 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Synuclein PF01387.12 ETO32110.1 - 0.14 12.0 0.5 0.3 10.9 0.1 1.7 2 0 0 2 2 2 0 Synuclein Neur_chan_memb PF02932.11 ETO32111.1 - 0.013 15.4 0.9 0.013 15.4 0.6 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region YqfQ PF14181.1 ETO32111.1 - 9.7 6.2 10.5 1.1 9.2 4.1 1.8 2 0 0 2 2 2 0 YqfQ-like protein CENP-B_dimeris PF09026.5 ETO32112.1 - 0.03 14.5 3.3 0.056 13.6 2.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain AAA_9 PF12781.2 ETO32112.1 - 0.063 12.1 0.2 0.47 9.2 0.0 1.9 1 1 1 2 2 2 0 ATP-binding dynein motor region D5 Spt5_N PF11942.3 ETO32112.1 - 0.51 10.9 10.7 1.4 9.6 7.4 1.8 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Myb_DNA-bind_3 PF12776.2 ETO32113.1 - 0.032 14.8 2.7 0.044 14.4 1.8 1.4 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain Cnl2_NKP2 PF09447.5 ETO32113.1 - 0.11 12.2 1.1 0.26 10.9 0.2 2.1 2 0 0 2 2 2 0 Cnl2/NKP2 family protein PFEMP PF03011.10 ETO32113.1 - 0.18 12.1 5.2 0.23 11.7 3.6 1.2 1 0 0 1 1 1 0 PFEMP DBL domain Hus1 PF04005.7 ETO32114.1 - 0.096 11.6 0.3 0.13 11.1 0.2 1.2 1 0 0 1 1 1 0 Hus1-like protein Colicin_immun PF09204.5 ETO32115.1 - 0.061 13.4 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Bacterial self-protective colicin-like immunity DUF1625 PF07787.7 ETO32116.1 - 0.29 10.3 9.3 0.46 9.6 6.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1625) PIG-F PF06699.6 ETO32116.1 - 0.68 9.8 11.2 0.97 9.3 7.3 1.7 1 1 0 1 1 1 0 GPI biosynthesis protein family Pig-F DUF211 PF02680.9 ETO32117.1 - 0.23 11.2 1.9 3.7 7.4 0.1 2.3 1 1 1 2 2 2 0 Uncharacterized ArCR, COG1888 WD40 PF00400.27 ETO32118.1 - 9.1e-64 209.2 30.9 4.6e-12 45.3 0.1 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO32118.1 - 6.4e-12 44.3 5.3 0.0073 14.4 0.1 5.1 2 1 3 5 5 5 4 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO32118.1 - 0.032 14.0 0.5 0.72 9.6 0.1 3.3 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Mem_trans PF03547.13 ETO32118.1 - 0.048 11.9 0.2 0.041 12.1 0.2 1.1 1 0 0 1 1 1 0 Membrane transport protein CobU PF02283.11 ETO32118.1 - 1.9 7.8 6.2 4 6.8 4.3 1.5 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase DUF1068 PF06364.7 ETO32118.1 - 6 6.4 10.2 12 5.4 7.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) Glyco_hydro_63 PF03200.11 ETO32118.1 - 7.6 4.2 20.1 11 3.7 14.0 1.1 1 0 0 1 1 1 0 Mannosyl oligosaccharide glucosidase WD40 PF00400.27 ETO32119.1 - 1.5e-66 218.0 26.5 5.8e-12 44.9 0.5 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO32119.1 - 8.5e-12 43.9 8.3 0.0061 14.7 2.0 5.5 1 1 3 5 5 5 5 Nucleoporin Nup120/160 Golgin_A5 PF09787.4 ETO32119.1 - 0.012 14.1 9.2 0.017 13.6 6.4 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF1664 PF07889.7 ETO32119.1 - 0.059 13.1 4.8 0.11 12.2 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Atg14 PF10186.4 ETO32119.1 - 0.28 10.0 9.6 0.46 9.3 6.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2232 PF09991.4 ETO32119.1 - 3.7 6.4 5.1 5.1 6.0 3.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) MutS_V PF00488.16 ETO32120.1 - 1.3e-29 103.3 0.0 1.4e-29 103.1 0.0 1.0 1 0 0 1 1 1 1 MutS domain V B56 PF01603.15 ETO32121.1 - 6.3e-119 397.2 10.3 8.9e-119 396.7 7.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) RnaseA PF00074.15 ETO32121.1 - 0.17 12.1 7.3 12 6.1 0.0 2.4 2 0 0 2 2 2 0 Pancreatic ribonuclease WD40 PF00400.27 ETO32122.1 - 0.0024 17.6 0.0 0.0068 16.2 0.1 1.7 2 0 0 2 2 2 1 WD domain, G-beta repeat CD34_antigen PF06365.7 ETO32123.1 - 0.091 12.4 1.4 0.11 12.1 1.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family PP2C PF00481.16 ETO32124.1 - 1.6e-52 178.4 0.1 1.8e-52 178.2 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 ETO32124.1 - 4.4e-07 29.5 0.1 8.3e-07 28.6 0.1 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C DUF2624 PF11116.3 ETO32124.1 - 0.012 16.1 0.0 0.026 15.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) Pur_DNA_glyco PF02245.11 ETO32124.1 - 0.028 13.5 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 Methylpurine-DNA glycosylase (MPG) Glutaredoxin PF00462.19 ETO32124.1 - 0.082 12.9 0.0 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 Glutaredoxin PUB PF09409.5 ETO32125.1 - 2.3e-15 56.1 0.5 2.3e-15 56.1 0.3 1.4 2 0 0 2 2 2 1 PUB domain FliD_C PF07195.7 ETO32125.1 - 0.039 13.2 0.1 0.052 12.8 0.1 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus HTH_33 PF13592.1 ETO32125.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix Imm27 PF15573.1 ETO32126.1 - 0.013 14.7 0.1 0.014 14.6 0.1 1.1 1 0 0 1 1 1 0 Immunity protein 27 MMR1 PF08505.5 ETO32127.1 - 0.0042 17.1 10.2 0.0042 17.1 7.1 3.1 3 1 1 4 4 4 1 Mitochondrial Myo2 receptor-related protein Myb_DNA-bind_6 PF13921.1 ETO32127.1 - 0.012 15.7 0.4 0.033 14.2 0.3 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain Pkinase PF00069.20 ETO32128.1 - 1.6e-39 135.6 0.0 2.6e-39 134.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.27 ETO32128.1 - 6.4e-22 75.1 7.2 1e-05 24.4 0.0 4.7 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 ETO32128.1 - 6.5e-17 61.4 9.2 2.1e-06 27.7 1.8 4.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 ETO32128.1 - 5.1e-16 57.0 9.1 0.00065 19.3 0.0 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 ETO32128.1 - 8.3e-16 56.5 8.1 3.8e-05 22.8 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 ETO32128.1 - 1.2e-13 50.4 8.5 0.00025 20.5 0.0 4.7 2 1 3 5 5 5 5 EF-hand domain pair Pkinase_Tyr PF07714.12 ETO32128.1 - 2.7e-13 49.5 0.0 5e-13 48.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase EF-hand_4 PF12763.2 ETO32128.1 - 8.6e-05 22.2 2.1 0.46 10.2 0.0 3.1 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand EcKinase PF02958.15 ETO32128.1 - 0.015 14.4 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase SPARC_Ca_bdg PF10591.4 ETO32128.1 - 0.032 14.2 6.2 0.86 9.6 0.8 3.4 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region VCBS PF13517.1 ETO32128.1 - 0.084 13.2 0.0 1.6 9.1 0.0 2.5 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Kinase-like PF14531.1 ETO32128.1 - 0.085 11.8 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like CAP_GLY PF01302.20 ETO32129.1 - 3.5e-33 113.1 4.6 1.8e-18 65.9 0.8 2.4 2 0 0 2 2 2 2 CAP-Gly domain Merozoite_SPAM PF07133.6 ETO32130.1 - 2.5 7.9 18.0 4.1 7.2 12.5 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) RNA_polI_A34 PF08208.6 ETO32130.1 - 5.3 6.6 25.5 0.85 9.2 13.6 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Kelch_6 PF13964.1 ETO32131.1 - 0.0022 18.0 0.5 0.12 12.6 0.0 3.0 2 1 1 3 3 3 1 Kelch motif EFG_IV PF03764.13 ETO32132.1 - 1.1e-12 47.6 0.0 1.5e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor G, domain IV Ribosomal_S30 PF04758.9 ETO32132.1 - 0.13 12.0 0.5 0.13 12.0 0.3 1.5 2 0 0 2 2 2 0 Ribosomal protein S30 Kelch_1 PF01344.20 ETO32133.1 - 6.5e-09 35.2 6.1 4e-05 23.0 0.3 4.8 5 0 0 5 5 5 1 Kelch motif Kelch_5 PF13854.1 ETO32133.1 - 1.5e-06 28.0 2.4 0.027 14.4 0.1 4.9 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 ETO32133.1 - 0.00035 20.6 6.2 0.085 13.0 0.4 4.9 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.10 ETO32133.1 - 0.0024 17.5 4.1 0.43 10.4 0.2 4.7 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.1 ETO32133.1 - 0.0074 16.0 0.1 0.92 9.3 0.0 3.3 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO32133.1 - 0.022 14.9 0.4 0.18 12.0 0.0 2.8 4 0 0 4 4 4 0 Galactose oxidase, central domain Copper-bind PF00127.15 ETO32133.1 - 0.1 12.8 0.8 0.44 10.8 0.1 2.1 2 0 0 2 2 2 0 Copper binding proteins, plastocyanin/azurin family NACHT PF05729.7 ETO32135.1 - 3.8e-05 23.4 0.1 6.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 ETO32135.1 - 0.0018 17.2 0.0 0.006 15.4 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.1 ETO32135.1 - 0.0026 17.7 0.0 0.0041 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Torsin PF06309.6 ETO32135.1 - 0.0058 16.5 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Torsin AAA_19 PF13245.1 ETO32135.1 - 0.0081 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain DAP3 PF10236.4 ETO32135.1 - 0.015 14.2 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.1 ETO32135.1 - 0.016 15.3 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 ETO32135.1 - 0.017 15.2 0.2 0.23 11.6 0.0 2.4 2 1 1 3 3 3 0 RNA helicase DUF2075 PF09848.4 ETO32135.1 - 0.032 13.2 0.3 0.1 11.5 0.0 1.9 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 ETO32135.1 - 0.043 13.2 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 ETO32135.1 - 0.05 13.0 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.1 ETO32135.1 - 0.12 11.9 0.1 0.34 10.4 0.0 1.7 1 1 1 2 2 2 0 AAA domain Gp37_Gp68 PF07505.6 ETO32138.1 - 0.012 14.7 1.9 0.015 14.5 1.3 1.1 1 0 0 1 1 1 0 Phage protein Gp37/Gp68 Neisseria_TspB PF05616.8 ETO32139.1 - 0.038 12.3 6.3 0.05 11.9 4.4 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein HA2 PF04408.18 ETO32140.1 - 1.1e-21 76.6 0.0 2.1e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 ETO32140.1 - 1e-14 54.1 0.1 2.9e-14 52.6 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 ETO32140.1 - 1.8e-12 47.1 0.0 4.1e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold ResIII PF04851.10 ETO32140.1 - 0.0011 18.7 0.7 0.95 9.2 0.0 2.5 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit T2SE PF00437.15 ETO32140.1 - 0.0013 17.6 0.0 0.0025 16.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DEAD PF00270.24 ETO32140.1 - 0.0014 18.1 1.9 0.65 9.4 0.1 2.6 1 1 1 2 2 2 2 DEAD/DEAH box helicase AAA_22 PF13401.1 ETO32140.1 - 0.0021 18.1 0.0 0.0077 16.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 ETO32140.1 - 0.0074 15.7 0.3 0.026 13.9 0.0 1.9 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain KaiC PF06745.8 ETO32140.1 - 0.01 14.9 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 KaiC FtsK_SpoIIIE PF01580.13 ETO32140.1 - 0.013 15.0 0.1 0.032 13.7 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Miro PF08477.8 ETO32140.1 - 0.024 15.1 0.3 0.063 13.7 0.2 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_23 PF13476.1 ETO32140.1 - 0.03 14.6 0.1 0.089 13.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain Arch_ATPase PF01637.13 ETO32140.1 - 0.031 13.9 0.1 0.074 12.7 0.1 1.6 1 0 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 ETO32140.1 - 0.042 13.3 0.1 0.11 12.0 0.0 1.7 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 ETO32140.1 - 0.043 13.7 0.0 1 9.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain SRPRB PF09439.5 ETO32140.1 - 0.06 12.5 0.4 6.8 5.8 0.0 2.7 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit PhoH PF02562.11 ETO32140.1 - 0.069 12.3 0.2 0.47 9.6 0.2 2.1 1 1 0 1 1 1 0 PhoH-like protein TrwB_AAD_bind PF10412.4 ETO32140.1 - 0.1 11.1 0.3 0.47 9.0 0.0 2.1 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain SRP54 PF00448.17 ETO32140.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.1 ETO32140.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 ETO32140.1 - 0.16 11.7 0.0 0.45 10.2 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 ETO32140.1 - 0.29 11.9 2.4 2 9.2 0.8 3.0 3 0 0 3 3 3 0 AAA domain WD40 PF00400.27 ETO32141.1 - 9.7e-56 183.7 28.5 4.7e-11 42.1 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO32141.1 - 2.3e-10 39.2 5.0 0.0024 16.1 0.0 4.5 3 1 2 5 5 5 4 Nucleoporin Nup120/160 DUF851 PF05867.6 ETO32141.1 - 0.039 13.1 0.0 0.082 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF851) DUF4604 PF15377.1 ETO32142.1 - 1.5 9.0 5.5 1.7 8.8 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) CENP-B_dimeris PF09026.5 ETO32142.1 - 1.6 8.9 13.0 0.17 12.1 4.2 2.5 2 1 0 2 2 2 0 Centromere protein B dimerisation domain DUF2457 PF10446.4 ETO32142.1 - 3.2 6.3 6.5 3.8 6.1 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Spt5_N PF11942.3 ETO32142.1 - 5.1 7.7 11.0 7.7 7.2 7.7 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal eRF1_1 PF03463.10 ETO32143.1 - 1.2e-18 66.9 0.1 1.8e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 ETO32143.1 - 1.4e-14 54.5 0.0 4.1e-14 53.0 0.0 1.8 1 1 1 2 2 2 1 eRF1 domain 2 DUF3800 PF12686.2 ETO32143.1 - 0.03 13.9 0.1 0.044 13.4 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) TPR_1 PF00515.23 ETO32144.1 - 0.0018 17.7 0.6 0.0045 16.5 0.4 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO32144.1 - 0.22 11.4 0.2 0.22 11.4 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETO32144.1 - 1.1 9.2 6.2 0.78 9.6 0.7 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.27 ETO32145.1 - 3.6e-30 102.7 11.3 3.6e-10 39.3 0.5 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO32145.1 - 2e-08 32.8 1.4 0.00044 18.5 0.0 2.9 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO32145.1 - 0.00036 19.3 2.1 0.006 15.3 1.4 2.1 1 1 0 1 1 1 1 Nup133 N terminal like DUF4221 PF13970.1 ETO32145.1 - 0.00096 18.5 2.4 0.087 12.1 0.4 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4221) HAD PF12710.2 ETO32145.1 - 0.053 13.6 0.3 5.3 7.1 0.0 2.1 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Kelch_1 PF01344.20 ETO32146.1 - 2.1e-08 33.5 4.7 1.9e-05 24.1 0.6 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 ETO32146.1 - 1.3e-06 27.9 6.6 0.0088 15.7 0.1 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 ETO32146.1 - 9.7e-05 22.3 6.2 0.74 10.0 0.3 4.9 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO32146.1 - 0.00022 20.9 1.2 0.45 10.3 0.0 3.6 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO32146.1 - 0.00032 20.5 2.8 1.8 8.5 0.2 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO32146.1 - 0.019 15.1 0.1 2.7 8.2 0.0 3.8 6 0 0 6 6 6 0 Galactose oxidase, central domain WD40 PF00400.27 ETO32148.1 - 2.9e-77 252.0 17.1 9.4e-13 47.5 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO32148.1 - 7.1e-14 51.9 0.0 3.3e-06 26.9 0.0 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO32148.1 - 1.5e-09 36.5 5.3 0.041 12.0 0.0 5.3 1 1 4 5 5 5 5 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO32148.1 - 4.9e-06 26.1 0.3 6e-05 22.6 0.1 2.4 2 1 1 3 3 3 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO32148.1 - 1.2e-05 23.8 2.8 0.37 9.0 0.0 3.0 2 1 1 3 3 3 3 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO32148.1 - 2.7e-05 23.0 9.5 0.83 8.3 0.6 5.6 1 1 4 5 5 5 2 Nup133 N terminal like Coatomer_WDAD PF04053.9 ETO32148.1 - 0.0003 19.7 0.7 0.22 10.2 0.1 2.4 1 1 1 2 2 2 2 Coatomer WD associated region Resistin PF06954.6 ETO32148.1 - 0.0018 18.5 0.1 5.7 7.2 0.0 3.8 3 1 3 6 6 6 2 Resistin PD40 PF07676.7 ETO32148.1 - 0.0052 16.4 13.6 4.3 7.1 0.0 5.9 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat DUF1652 PF07865.6 ETO32148.1 - 0.009 15.5 0.0 3.7 7.2 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1652) DUF2616 PF11077.3 ETO32149.1 - 0.021 14.3 0.3 0.024 14.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) Myb_DNA-binding PF00249.26 ETO32151.1 - 1e-08 35.0 0.0 2.3e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain TMEM154 PF15102.1 ETO32151.1 - 5.7e-05 22.8 4.9 5.7e-05 22.8 3.4 2.9 3 1 0 3 3 3 1 TMEM154 protein family Rifin_STEVOR PF02009.11 ETO32151.1 - 0.00013 21.7 2.9 0.00013 21.7 2.0 3.9 3 1 1 4 4 3 1 Rifin/stevor family DUF912 PF06024.7 ETO32151.1 - 0.00042 20.3 2.1 0.00042 20.3 1.5 4.3 4 0 0 4 4 3 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Myb_DNA-bind_6 PF13921.1 ETO32151.1 - 0.0031 17.5 0.0 0.0076 16.3 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain DAG1 PF05454.6 ETO32151.1 - 0.0045 16.1 0.3 0.0095 15.1 0.2 1.5 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) AA_permease_2 PF13520.1 ETO32151.1 - 0.012 14.1 9.1 0.79 8.1 3.4 2.3 2 0 0 2 2 2 0 Amino acid permease DUF4448 PF14610.1 ETO32151.1 - 0.037 13.5 6.2 4.8 6.6 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) DUF1183 PF06682.7 ETO32151.1 - 0.051 13.1 0.4 3.9 6.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) Gastrin PF00918.12 ETO32151.1 - 0.093 13.5 1.6 0.19 12.5 0.4 2.1 2 0 0 2 2 1 0 Gastrin/cholecystokinin family ATG27 PF09451.5 ETO32151.1 - 0.17 11.0 2.3 10 5.2 0.8 2.3 2 0 0 2 2 2 0 Autophagy-related protein 27 MRAP PF15183.1 ETO32151.1 - 0.43 10.2 5.6 1 8.9 0.1 2.8 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family AJAP1_PANP_C PF15298.1 ETO32151.1 - 0.59 9.9 4.6 0.099 12.5 0.3 1.7 2 0 0 2 2 2 0 AJAP1/PANP C-terminus MMPL PF03176.10 ETO32151.1 - 1.8 7.1 5.8 0.31 9.7 1.4 1.6 2 0 0 2 2 2 0 MMPL family Mid2 PF04478.7 ETO32151.1 - 2.8 7.3 9.6 7.3 5.9 6.7 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Protocadherin PF08374.6 ETO32151.1 - 3.1 7.3 19.3 1.6 8.2 3.5 2.4 2 0 0 2 2 2 0 Protocadherin Shisa PF13908.1 ETO32151.1 - 3.1 7.9 18.3 1.1 9.4 3.1 3.7 4 0 0 4 4 4 0 Wnt and FGF inhibitory regulator Baculo_11_kDa PF06143.6 ETO32151.1 - 4.4 6.7 19.6 3.6 7.0 5.2 3.5 3 0 0 3 3 3 0 Baculovirus 11 kDa family DnaB_2 PF07261.6 ETO32153.1 - 0.0053 16.3 0.1 2.7 7.6 0.0 2.4 2 0 0 2 2 2 2 Replication initiation and membrane attachment HMG_box_5 PF14887.1 ETO32153.1 - 0.29 10.9 7.3 23 4.8 0.5 3.3 3 0 0 3 3 3 0 HMG (high mobility group) box 5 ING PF12998.2 ETO32153.1 - 3.6 7.8 8.2 1.8 8.8 3.5 2.1 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding TTL PF03133.10 ETO32154.1 - 3.1e-96 321.7 0.5 4e-96 321.4 0.3 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 ETO32154.1 - 9.4e-06 24.6 0.1 0.00014 20.7 0.0 2.3 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 ETO32154.1 - 0.016 14.9 0.0 0.037 13.7 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain CP_ATPgrasp_1 PF04174.8 ETO32154.1 - 0.046 12.3 0.0 0.2 10.2 0.0 1.8 2 0 0 2 2 2 0 A circularly permuted ATPgrasp CUE PF02845.11 ETO32156.1 - 0.0012 18.3 0.3 0.0034 16.8 0.2 1.8 1 0 0 1 1 1 1 CUE domain PUB PF09409.5 ETO32156.1 - 0.0026 17.4 1.3 0.015 15.0 0.9 2.3 1 1 0 1 1 1 1 PUB domain ACDC PF14733.1 ETO32156.1 - 8.2 6.6 8.9 0.23 11.5 0.2 2.5 3 0 0 3 3 3 0 AP2-coincident C-terminal adh_short PF00106.20 ETO32158.1 - 1.7e-15 57.3 0.1 2.2e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETO32158.1 - 1.5e-06 28.1 0.0 1.8e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETO32158.1 - 1.7e-06 27.8 0.2 3.2e-06 26.9 0.1 1.4 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 ETO32158.1 - 0.026 13.4 0.1 0.03 13.2 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_18 PF12847.2 ETO32158.1 - 0.074 13.6 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF3022 PF11226.3 ETO32158.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3022) DUF3545 PF12065.3 ETO32159.1 - 6.9 6.4 9.8 0.92 9.3 0.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3545) His_Phos_1 PF00300.17 ETO32160.1 - 1.6e-36 125.8 0.0 2.1e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Kelch_4 PF13418.1 ETO32161.1 - 3.9e-05 23.3 0.5 0.0061 16.3 0.0 3.4 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO32161.1 - 0.00076 19.5 4.2 0.3 11.3 0.1 4.0 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 ETO32161.1 - 0.0031 17.4 2.6 1.1 9.3 0.6 3.9 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 ETO32161.1 - 0.004 16.6 2.5 2.7 7.6 0.0 4.0 4 0 0 4 4 4 1 Kelch motif DUF3865 PF12981.2 ETO32162.1 - 0.029 14.1 0.6 0.039 13.7 0.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3865) SNARE_assoc PF09335.6 ETO32163.1 - 4.7e-08 33.2 1.3 4.7e-08 33.2 0.9 2.4 2 1 0 2 2 2 1 SNARE associated Golgi protein RDD PF06271.7 ETO32163.1 - 0.025 14.4 4.1 1.3 8.9 0.1 2.4 2 0 0 2 2 2 0 RDD family Sigma_reg_N PF13800.1 ETO32163.1 - 0.063 13.3 0.4 0.063 13.3 0.3 1.7 2 0 0 2 2 2 0 Sigma factor regulator N-terminal FixQ PF05545.6 ETO32163.1 - 0.15 11.7 2.0 0.2 11.3 0.1 2.2 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF3139 PF11337.3 ETO32163.1 - 0.2 11.9 2.4 1 9.6 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) WD40 PF00400.27 ETO32164.1 - 4.8e-74 241.8 27.2 2.9e-11 42.7 0.0 10.7 10 0 0 10 10 10 9 WD domain, G-beta repeat PD40 PF07676.7 ETO32164.1 - 7e-05 22.3 0.0 1.7 8.3 0.0 3.7 3 0 0 3 3 3 3 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 ETO32164.1 - 0.85 9.0 4.1 40 3.6 0.0 4.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 ETO32165.1 - 1.7e-58 192.4 27.5 2e-10 40.1 0.3 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO32165.1 - 9.3e-07 27.3 5.6 0.08 11.0 0.0 5.1 1 1 2 4 4 4 3 Nucleoporin Nup120/160 SEFIR PF08357.6 ETO32166.1 - 0.21 11.6 3.6 0.24 11.4 2.1 1.3 1 1 0 1 1 1 0 SEFIR domain PBP_sp32 PF07222.7 ETO32166.1 - 8.3 5.5 8.0 11 5.1 5.6 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF3464 PF11947.3 ETO32166.1 - 10 5.5 6.8 16 4.9 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) UCH PF00443.24 ETO32169.1 - 3.7e-24 85.2 1.3 3.7e-24 85.2 0.9 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO32169.1 - 0.0003 20.3 1.0 0.0003 20.3 0.7 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase M PF02370.11 ETO32169.1 - 0.069 13.5 4.7 0.069 13.5 3.2 3.2 2 2 1 3 3 2 0 M protein repeat Guanylate_cyc PF00211.15 ETO32169.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain DUF4208 PF13907.1 ETO32169.1 - 0.46 10.7 6.8 2.7 8.2 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4208) YPEB PF14620.1 ETO32169.1 - 0.55 9.1 7.8 0.69 8.8 5.4 1.3 1 1 0 1 1 1 0 YpeB sporulation Xpo1 PF08389.7 ETO32169.1 - 1.3 8.9 7.3 0.24 11.3 0.2 2.4 1 1 1 3 3 3 0 Exportin 1-like protein Spc24 PF08286.6 ETO32169.1 - 1.4 8.6 13.7 0.27 10.9 6.9 1.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Vfa1 PF08432.5 ETO32169.1 - 1.5 8.8 11.3 2.3 8.1 7.8 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 GrpE PF01025.14 ETO32169.1 - 2.5 7.6 9.7 4.9 6.6 5.1 2.1 2 0 0 2 2 2 0 GrpE AAA_13 PF13166.1 ETO32169.1 - 2.8 6.2 16.0 2 6.7 9.9 1.6 1 1 1 2 2 2 0 AAA domain OmpH PF03938.9 ETO32169.1 - 3.6 7.4 21.7 5.8 6.8 15.1 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) EMP24_GP25L PF01105.19 ETO32169.1 - 8.4 6.0 9.3 31 4.2 3.8 2.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD FlxA PF14282.1 ETO32169.1 - 9.4 6.2 15.6 1.9 8.4 8.2 1.8 2 0 0 2 2 1 0 FlxA-like protein zf-RING_2 PF13639.1 ETO32170.1 - 5.6e-09 35.6 2.9 5.6e-09 35.6 2.0 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 ETO32170.1 - 8.9e-06 25.2 1.0 8.9e-06 25.2 0.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETO32170.1 - 1e-05 25.5 1.3 1e-05 25.5 0.9 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 ETO32170.1 - 0.0027 17.3 3.2 0.0027 17.3 2.2 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 ETO32170.1 - 0.0045 16.9 1.6 0.0045 16.9 1.1 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO32170.1 - 0.0049 16.5 2.8 0.0049 16.5 1.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 ETO32170.1 - 0.0078 16.0 1.2 0.018 14.8 0.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PfUIS3 PF11567.3 ETO32170.1 - 0.52 10.4 4.5 0.33 11.1 1.3 2.0 2 0 0 2 2 2 0 Plasmodium falciparum UIS3 membrane protein zf-RING_2 PF13639.1 ETO32171.1 - 4.4e-09 36.0 9.6 1.2e-08 34.6 6.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO32171.1 - 2.7e-06 27.3 10.2 2.7e-06 27.3 7.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO32171.1 - 3.8e-06 26.4 6.8 3.8e-06 26.4 4.7 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 ETO32171.1 - 7.5e-05 22.3 5.9 7.5e-05 22.3 4.1 2.2 2 0 0 2 2 2 1 PHD-finger zf-rbx1 PF12678.2 ETO32171.1 - 0.00055 19.9 12.0 0.00063 19.7 6.2 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 ETO32171.1 - 0.0012 18.5 9.1 0.0021 17.7 5.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 ETO32171.1 - 0.0052 16.6 5.9 0.0052 16.6 4.1 2.3 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Nab1 PF04902.7 ETO32171.1 - 0.04 13.4 0.1 0.27 10.7 0.0 2.2 3 0 0 3 3 3 0 Conserved region in Nab1 zf-Apc11 PF12861.2 ETO32171.1 - 0.099 12.4 10.3 0.045 13.5 4.9 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.2 ETO32171.1 - 0.44 10.4 8.8 4.6 7.1 1.3 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-MIZ PF02891.15 ETO32171.1 - 0.46 10.0 9.4 0.99 8.9 6.5 1.6 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-Nse PF11789.3 ETO32171.1 - 1.1 8.8 5.2 2.6 7.6 3.6 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-Di19 PF05605.7 ETO32171.1 - 5.7 7.1 9.8 2.2 8.4 4.7 1.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-HC5HC2H PF13771.1 ETO32171.1 - 7.7 6.7 12.8 0.22 11.6 3.5 2.2 2 1 1 3 3 2 0 PHD-like zinc-binding domain Phage_cap_E PF03864.10 ETO32173.1 - 0.06 12.2 0.0 0.067 12.1 0.0 1.1 1 0 0 1 1 1 0 Phage major capsid protein E Cbl_N PF02262.11 ETO32173.1 - 0.085 12.5 4.1 0.079 12.6 1.2 2.1 1 1 2 3 3 3 0 CBL proto-oncogene N-terminal domain 1 CLN3 PF02487.12 ETO32174.1 - 6.8e-19 67.9 11.5 8.3e-19 67.6 8.0 1.0 1 0 0 1 1 1 1 CLN3 protein DUF3753 PF12575.3 ETO32174.1 - 0.11 12.3 1.8 0.18 11.6 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) DUF1469 PF07332.6 ETO32174.1 - 0.54 10.0 2.1 6.2 6.5 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Grp1_Fun34_YaaH PF01184.14 ETO32175.1 - 0.009 15.3 0.3 0.01 15.1 0.2 1.2 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family WD40 PF00400.27 ETO32176.1 - 4e-34 115.2 18.5 3.9e-10 39.2 0.7 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat WD40 PF00400.27 ETO32177.1 - 3e-82 267.8 17.4 1.4e-13 50.1 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO32177.1 - 1.4e-13 51.0 0.1 1.9e-06 27.7 0.0 3.6 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO32177.1 - 2.3e-05 22.9 0.6 0.15 10.3 0.0 3.1 1 1 3 4 4 4 4 Cytochrome D1 heme domain Str_synth PF03088.11 ETO32177.1 - 0.00014 21.8 0.0 4.3 7.4 0.0 4.5 5 2 0 5 5 5 2 Strictosidine synthase Gmad1 PF10647.4 ETO32177.1 - 0.004 16.6 0.0 0.021 14.2 0.0 2.0 2 0 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain DPPIV_N PF00930.16 ETO32177.1 - 0.03 12.9 0.1 1.2 7.6 0.0 2.7 1 1 2 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Resistin PF06954.6 ETO32177.1 - 0.043 14.1 0.0 48 4.3 0.0 3.8 3 2 1 4 4 4 0 Resistin PD40 PF07676.7 ETO32177.1 - 0.11 12.2 12.1 4 7.2 0.1 4.8 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat NodS PF05401.6 ETO32177.1 - 0.11 11.8 0.0 1.1 8.6 0.0 2.3 1 1 0 2 2 2 0 Nodulation protein S (NodS) BBS2_Mid PF14783.1 ETO32177.1 - 0.49 10.1 3.9 65 3.3 0.5 4.6 3 2 2 5 5 5 0 Ciliary BBSome complex subunit 2, middle region Proteasome_A_N PF10584.4 ETO32177.1 - 1.1 8.6 12.9 8.3 5.8 0.0 5.1 4 1 1 5 5 5 0 Proteasome subunit A N-terminal signature SAM_1 PF00536.25 ETO32179.1 - 2.5e-06 27.5 0.2 8.9e-06 25.7 0.1 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO32179.1 - 0.00044 20.0 0.3 0.0016 18.2 0.1 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Ank_2 PF12796.2 ETO32180.1 - 0.00064 20.0 0.8 0.095 13.0 0.2 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) CENP-B_dimeris PF09026.5 ETO32180.1 - 0.099 12.8 5.0 0.58 10.4 0.1 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Peptidase_M16 PF00675.15 ETO32181.1 - 7.3e-27 93.9 0.2 9.9e-27 93.5 0.2 1.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 ETO32182.1 - 6.2e-18 65.1 0.2 1.1e-07 31.7 0.1 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain DUF2252 PF10009.4 ETO32182.1 - 0.14 11.0 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) WD40 PF00400.27 ETO32183.1 - 7.1e-67 219.0 22.3 2.6e-11 42.9 0.1 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO32183.1 - 2.6e-11 42.3 1.3 0.061 11.4 0.1 5.7 1 1 2 4 4 4 4 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO32183.1 - 8.4e-06 26.0 4.6 8.4e-06 26.0 3.2 2.8 2 0 0 2 2 2 1 TRAF-type zinc finger Nucleoporin_N PF08801.6 ETO32183.1 - 6.3e-05 21.8 7.7 0.042 12.6 0.1 4.3 2 1 1 3 3 3 2 Nup133 N terminal like DUF3601 PF12208.3 ETO32183.1 - 0.0021 17.9 2.2 10 6.1 0.0 5.5 4 1 2 6 6 6 1 Domain of unknown function (DUF3601) BicD PF09730.4 ETO32183.1 - 0.028 12.7 14.2 0.039 12.3 9.8 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D DUF342 PF03961.8 ETO32183.1 - 0.92 7.8 9.5 1.4 7.2 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AAA_33 PF13671.1 ETO32184.1 - 5.4e-07 29.5 0.1 1.9e-06 27.7 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ETO32184.1 - 0.019 15.7 0.3 0.034 14.9 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 ETO32184.1 - 0.87 9.9 4.0 0.3 11.4 0.3 2.1 2 0 0 2 2 2 0 AAA domain DUF334 PF03904.8 ETO32184.1 - 1.3 8.3 6.9 2.5 7.3 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF334) NfeD PF01957.13 ETO32185.1 - 0.043 13.9 0.1 1.1 9.3 0.0 2.2 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding DUF92 PF01940.11 ETO32185.1 - 0.14 11.2 0.1 0.22 10.6 0.1 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF92 SR-25 PF10500.4 ETO32187.1 - 0.00052 19.5 6.2 0.00071 19.1 4.3 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein ORC6 PF05460.8 ETO32187.1 - 0.0095 15.0 2.0 0.013 14.6 1.4 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) DUF1117 PF06547.7 ETO32187.1 - 0.013 15.5 0.9 0.015 15.3 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) Phage_pRha PF09669.5 ETO32187.1 - 0.028 14.7 0.2 0.086 13.2 0.0 1.8 2 0 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) DUF3752 PF12572.3 ETO32187.1 - 0.033 14.2 0.6 0.042 13.9 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) DUF3582 PF12122.3 ETO32187.1 - 0.044 13.7 0.0 6.6 6.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3582) YojJ PF10372.4 ETO32187.1 - 0.099 12.5 1.1 3.2 7.6 0.0 2.6 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus Histone PF00125.19 ETO32187.1 - 0.11 12.6 1.1 0.27 11.3 0.8 1.7 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 BRF1 PF07741.8 ETO32187.1 - 0.34 11.1 2.7 0.92 9.7 1.8 2.0 1 1 0 1 1 1 0 Brf1-like TBP-binding domain PPP5 PF08321.7 ETO32187.1 - 0.64 10.0 2.8 0.75 9.8 0.4 2.1 2 1 1 3 3 3 0 PPP5 TPR repeat region DUF755 PF05501.6 ETO32187.1 - 6.4 6.8 16.7 14 5.7 11.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF755) WD40 PF00400.27 ETO32188.1 - 6.6e-48 158.9 33.7 3.7e-12 45.6 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO32188.1 - 7.4e-07 27.6 5.5 0.24 9.4 0.0 4.9 1 1 2 4 4 4 4 Nucleoporin Nup120/160 EFG_IV PF03764.13 ETO32189.1 - 7.1e-26 90.1 0.0 1.4e-25 89.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 ETO32189.1 - 1.2e-14 53.8 0.0 2.2e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 ETO32189.1 - 1.1e-09 37.9 0.0 2e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 ETO32189.1 - 0.00059 19.9 0.1 0.0039 17.2 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu domain 2 WD40 PF00400.27 ETO32190.1 - 3.4e-53 175.7 13.9 2.2e-11 43.1 0.1 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO32190.1 - 2e-10 40.7 0.2 5.1e-05 23.0 0.0 3.8 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Kelch_5 PF13854.1 ETO32190.1 - 6.1e-07 29.2 0.5 0.66 10.0 0.0 4.7 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.1 ETO32190.1 - 1.1e-06 28.5 0.3 0.0076 16.3 0.0 3.7 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO32190.1 - 2.7e-06 27.3 10.5 0.067 13.3 0.1 5.7 5 1 1 6 6 5 2 Kelch motif Kelch_4 PF13418.1 ETO32190.1 - 3.2e-05 23.6 3.1 0.35 10.6 0.1 4.2 4 0 0 4 4 4 2 Galactose oxidase, central domain Nbas_N PF15492.1 ETO32190.1 - 6.9e-05 22.0 0.7 0.65 9.0 0.0 3.9 4 0 0 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Kelch_2 PF07646.10 ETO32190.1 - 0.00021 20.9 3.9 0.37 10.6 0.3 4.3 5 0 0 5 5 5 2 Kelch motif Cytochrom_D1 PF02239.11 ETO32190.1 - 0.0009 17.6 0.7 1.3 7.2 0.0 3.2 2 1 1 3 3 3 2 Cytochrome D1 heme domain Kelch_1 PF01344.20 ETO32190.1 - 0.0013 18.2 8.5 1 8.9 0.3 3.7 3 0 0 3 3 3 2 Kelch motif PQQ_2 PF13360.1 ETO32190.1 - 0.024 14.0 0.2 2 7.7 0.1 2.4 1 1 1 2 2 2 0 PQQ-like domain BBS2_Mid PF14783.1 ETO32190.1 - 0.031 14.0 0.1 3.8 7.3 0.0 3.5 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region PD40 PF07676.7 ETO32190.1 - 0.086 12.5 4.0 16 5.3 0.0 4.9 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Ank PF00023.25 ETO32191.1 - 0.0024 17.5 0.0 0.006 16.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 ETO32191.1 - 0.04 14.2 0.1 0.12 12.7 0.0 1.7 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO32191.1 - 0.074 13.5 0.2 0.83 10.2 0.2 2.2 1 1 1 2 2 2 0 Ankyrin repeats (many copies) BPL_C PF02237.12 ETO32193.1 - 0.088 12.5 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain RFC1 PF08519.7 ETO32195.1 - 0.1 12.3 1.3 0.16 11.7 0.4 1.6 1 1 0 1 1 1 0 Replication factor RFC1 C terminal domain PXA PF02194.10 ETO32197.1 - 0.099 12.1 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 PXA domain Pox_TAA1 PF03295.9 ETO32197.1 - 0.16 11.6 0.8 7.4 6.3 0.1 2.3 2 0 0 2 2 2 0 Poxvirus trans-activator protein A1 C-terminal NA37 PF04245.8 ETO32198.1 - 0.02 14.2 2.5 0.031 13.6 1.7 1.3 1 1 0 1 1 1 0 37-kD nucleoid-associated bacterial protein YcgL PF05166.8 ETO32198.1 - 0.13 12.4 4.5 0.69 10.0 2.2 2.6 2 1 0 2 2 2 0 YcgL domain ADK PF00406.17 ETO32199.1 - 3.7e-07 30.1 0.6 9.5e-07 28.8 0.3 1.8 2 0 0 2 2 2 1 Adenylate kinase MMR_HSR1 PF01926.18 ETO32199.1 - 0.0036 17.2 0.3 0.0061 16.5 0.2 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 ETO32199.1 - 0.011 16.5 0.0 0.041 14.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 ETO32199.1 - 0.014 15.8 0.4 0.14 12.6 0.3 2.3 1 1 0 1 1 1 0 Miro-like protein AAA_18 PF13238.1 ETO32199.1 - 0.027 14.7 0.0 0.066 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 ETO32199.1 - 0.04 13.4 0.4 6.3 6.2 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FeoB_N PF02421.13 ETO32199.1 - 0.067 12.4 0.0 0.23 10.7 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.1 ETO32199.1 - 0.1 12.6 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain UBX PF00789.15 ETO32200.1 - 1.9e-09 37.4 0.0 3.8e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 UBX domain PrgU PF09627.5 ETO32200.1 - 0.0025 17.4 0.4 1.8 8.1 0.1 2.3 2 0 0 2 2 2 2 PrgU-like protein Acetyltransf_3 PF13302.1 ETO32201.1 - 8.3e-20 71.4 0.0 1.6e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 ETO32201.1 - 0.031 14.2 1.3 0.14 12.1 0.9 2.2 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain KOW PF00467.24 ETO32202.1 - 0.34 10.7 4.8 0.17 11.6 0.9 2.5 3 1 1 4 4 4 0 KOW motif PIG-P PF08510.7 ETO32203.1 - 0.44 10.1 8.1 0.36 10.4 1.7 2.2 1 1 1 2 2 2 0 PIG-P TspO_MBR PF03073.10 ETO32204.1 - 2.3 7.7 7.7 0.8 9.2 1.9 2.0 1 1 1 2 2 2 0 TspO/MBR family SNARE PF05739.14 ETO32205.1 - 0.013 15.1 0.2 0.013 15.1 0.2 2.5 2 1 1 3 3 3 0 SNARE domain CENP-H PF05837.7 ETO32205.1 - 1.4 9.1 6.6 0.2 11.8 0.7 2.5 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Peptidase_C97 PF05903.9 ETO32206.1 - 3.8e-05 23.4 0.1 4.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain QH-AmDH_gamma PF08992.6 ETO32206.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, gamma subunit Glyco_hydro_47 PF01532.15 ETO32208.1 - 1.1e-46 159.4 0.3 1.4e-46 159.1 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_47 PF01532.15 ETO32209.1 - 2.3e-19 69.4 0.1 2.4e-19 69.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Ras PF00071.17 ETO32210.1 - 1.6e-45 154.4 0.1 2.1e-45 153.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO32210.1 - 8.1e-13 48.9 0.0 1.9e-12 47.7 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO32210.1 - 1.7e-07 30.6 0.0 2.4e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO32210.1 - 6.8e-05 22.3 0.0 9e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Reo_sigmaC PF04582.7 ETO32214.1 - 0.00049 19.3 0.9 0.00077 18.7 0.7 1.3 1 0 0 1 1 1 1 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 ETO32214.1 - 0.0014 18.3 12.2 0.0014 18.3 8.4 2.8 2 1 1 3 3 3 2 TATA element modulatory factor 1 DNA binding BLOC1_2 PF10046.4 ETO32214.1 - 0.0063 16.6 15.6 0.021 14.9 4.0 3.0 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Nup54 PF13874.1 ETO32214.1 - 0.012 15.2 3.6 0.031 13.9 2.5 1.7 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF641 PF04859.7 ETO32214.1 - 0.023 14.4 2.3 0.023 14.4 1.6 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) ACCA PF03255.9 ETO32214.1 - 0.039 13.5 8.3 0.017 14.6 3.6 1.9 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF1664 PF07889.7 ETO32214.1 - 0.054 13.3 13.2 0.055 13.2 2.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) zf-C3HC4_2 PF13923.1 ETO32214.1 - 0.096 12.7 5.1 0.71 9.9 3.5 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2457 PF10446.4 ETO32214.1 - 0.21 10.2 25.4 0.18 10.4 16.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2457) DUF2968 PF11180.3 ETO32214.1 - 0.21 10.9 6.8 0.38 10.1 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DASH_Dad3 PF08656.5 ETO32214.1 - 0.38 10.4 5.2 3.2 7.5 3.6 2.6 1 1 0 1 1 1 0 DASH complex subunit Dad3 NPV_P10 PF05531.7 ETO32214.1 - 0.54 10.5 10.6 6.6 7.0 7.4 2.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF2802 PF10975.3 ETO32214.1 - 1.2 8.9 6.6 0.75 9.5 0.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2802) DUF948 PF06103.6 ETO32214.1 - 4.3 7.2 7.6 13 5.7 5.2 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) RasGAP_C PF03836.10 ETO32215.1 - 0.00049 19.7 8.9 0.00049 19.7 6.2 2.4 1 1 1 2 2 2 1 RasGAP C-terminus Nucleoplasmin PF03066.10 ETO32215.1 - 0.0057 16.1 0.5 0.011 15.1 0.4 1.4 1 0 0 1 1 1 1 Nucleoplasmin Sipho_Gp157 PF05565.6 ETO32215.1 - 3.6 7.1 11.7 0.59 9.7 4.0 2.3 1 1 1 2 2 2 0 Siphovirus Gp157 WD40 PF00400.27 ETO32216.1 - 3.9e-45 150.1 16.5 9.5e-10 37.9 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO32216.1 - 3.1e-12 45.4 3.9 4.7e-05 21.7 0.1 4.9 1 1 4 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO32216.1 - 0.00074 18.3 7.5 1.1 7.8 0.7 3.7 2 1 1 3 3 3 3 Nup133 N terminal like YqzE PF14038.1 ETO32217.1 - 0.011 15.4 0.7 0.02 14.5 0.5 1.4 1 0 0 1 1 1 0 YqzE-like protein GLYCAM-1 PF05242.6 ETO32218.1 - 0.12 12.3 1.2 0.31 10.9 0.3 1.8 2 0 0 2 2 2 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) DUF3931 PF13082.1 ETO32219.1 - 2.8 7.8 5.6 6.5 6.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3931) PrmA PF06325.8 ETO32220.1 - 1.5e-05 24.3 0.9 0.0078 15.3 0.1 2.2 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) PRMT5 PF05185.11 ETO32220.1 - 5e-05 22.4 0.4 0.00016 20.7 0.0 1.8 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase Methyltransf_18 PF12847.2 ETO32220.1 - 0.00063 20.3 0.3 0.028 14.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain DUF633 PF04816.7 ETO32220.1 - 0.00086 18.7 1.0 0.0025 17.1 0.2 2.0 1 1 1 2 2 2 1 Family of unknown function (DUF633) Met_10 PF02475.11 ETO32220.1 - 0.0028 17.2 0.2 0.029 13.9 0.0 2.3 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_26 PF13659.1 ETO32220.1 - 0.003 17.5 0.0 0.0059 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO32220.1 - 0.0091 15.5 1.5 0.032 13.8 1.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain TPR_12 PF13424.1 ETO32221.1 - 1.3e-31 108.3 4.6 2.9e-13 49.5 0.7 3.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO32221.1 - 7.1e-19 67.2 7.4 2.4e-08 33.5 0.9 3.6 2 1 1 3 3 3 3 TPR repeat TPR_10 PF13374.1 ETO32221.1 - 6.6e-17 60.8 0.0 7.8e-05 22.4 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO32221.1 - 9.5e-17 59.4 1.5 0.00076 19.0 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO32221.1 - 2.5e-15 55.3 18.7 0.00041 19.8 0.8 5.7 4 2 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO32221.1 - 3.7e-13 48.2 12.0 0.0028 17.4 0.1 5.3 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO32221.1 - 2.2e-11 42.6 13.9 0.0036 16.9 0.5 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO32221.1 - 3.1e-08 33.5 1.3 0.78 10.3 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO32221.1 - 1.2e-05 25.0 6.2 0.67 10.3 0.5 4.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO32221.1 - 0.0001 22.6 0.0 4.6 8.1 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO32221.1 - 0.00022 21.7 0.0 0.0042 17.7 0.0 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat SNAP PF14938.1 ETO32221.1 - 0.00024 20.3 0.5 0.0009 18.4 0.0 2.1 2 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP SHNi-TPR PF10516.4 ETO32221.1 - 0.039 13.1 0.1 1.8 7.8 0.0 3.4 4 0 0 4 4 4 0 SHNi-TPR Apc3 PF12895.2 ETO32221.1 - 0.091 12.9 3.5 0.79 9.8 0.2 2.8 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Peptidase_C14 PF00656.17 ETO32222.1 - 3.4e-07 30.2 0.1 9.9e-07 28.7 0.1 1.8 1 1 0 1 1 1 1 Caspase domain ETRAMP PF09716.5 ETO32223.1 - 2.2 8.2 8.7 0.58 10.1 0.1 2.9 2 1 1 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) DZR PF12773.2 ETO32223.1 - 5.8 6.8 7.1 0.9 9.4 1.0 2.3 2 0 0 2 2 2 0 Double zinc ribbon tRNA-synt_2 PF00152.15 ETO32224.1 - 6.3e-69 232.3 0.1 7.8e-69 231.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 ETO32224.1 - 6.6e-09 35.3 0.1 0.00039 19.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) LRR_6 PF13516.1 ETO32226.1 - 4.2e-06 26.2 2.9 1.3 9.3 0.1 4.4 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.2 ETO32226.1 - 8.6e-06 25.2 5.0 0.32 10.6 0.2 4.3 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETO32226.1 - 5.6e-05 22.6 1.4 4.2 7.7 0.0 4.8 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 ETO32226.1 - 0.032 14.3 2.8 19 6.0 0.1 4.2 4 0 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 ETO32227.1 - 6.6e-10 38.0 18.9 0.053 13.6 0.1 5.5 5 0 0 5 5 5 5 Leucine Rich repeat GatB_Yqey PF02637.13 ETO32228.1 - 0.022 14.4 1.9 0.022 14.4 1.3 1.6 2 0 0 2 2 2 0 GatB domain DivIC PF04977.10 ETO32228.1 - 0.068 12.6 0.5 0.068 12.6 0.4 2.8 3 1 0 3 3 3 0 Septum formation initiator COG2 PF06148.6 ETO32228.1 - 0.078 12.8 4.0 0.065 13.0 0.5 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 FUN14 PF04930.10 ETO32228.1 - 0.42 10.9 4.9 0.85 9.9 0.3 2.3 2 1 0 2 2 2 0 FUN14 family DUF1664 PF07889.7 ETO32228.1 - 0.63 9.8 7.0 7.7 6.3 1.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) PspA_IM30 PF04012.7 ETO32228.1 - 1.1 8.5 8.0 3.1 7.1 0.7 2.1 2 0 0 2 2 2 0 PspA/IM30 family Seryl_tRNA_N PF02403.17 ETO32228.1 - 3.7 7.6 15.6 1 9.4 1.2 2.5 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Enkurin PF13864.1 ETO32228.1 - 3.8 7.7 11.2 0.59 10.3 2.6 2.2 2 0 0 2 2 2 0 Calmodulin-binding LOH1CR12 PF10158.4 ETO32228.1 - 4.7 7.0 8.9 0.53 10.0 2.6 1.9 2 0 0 2 2 2 0 Tumour suppressor protein ATP-grasp_2 PF08442.5 ETO32229.1 - 4.5e-07 29.4 0.1 0.0019 17.6 0.0 2.3 1 1 1 2 2 2 2 ATP-grasp domain Ligase_CoA PF00549.14 ETO32230.1 - 5.3e-07 29.3 0.0 1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 ETO32230.1 - 4.3e-06 27.1 0.1 1.5e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.1 ETO32230.1 - 0.12 12.0 0.0 0.43 10.1 0.0 1.8 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain Citrate_synt PF00285.16 ETO32231.1 - 7.2e-18 64.4 0.0 1.3e-15 57.0 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase PCI PF01399.22 ETO32232.1 - 0.00012 22.3 2.6 0.00018 21.7 0.3 2.3 2 1 0 2 2 2 1 PCI domain EST1_DNA_bind PF10373.4 ETO32232.1 - 0.1 11.7 1.1 0.12 11.5 0.8 1.1 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain Fe-S_assembly PF04384.8 ETO32233.1 - 0.31 11.4 3.0 0.21 11.9 0.7 1.8 2 0 0 2 2 2 0 Iron-sulphur cluster assembly Protein_K PF12283.3 ETO32234.1 - 0.017 14.9 0.1 0.06 13.2 0.0 2.0 1 1 1 2 2 2 0 Bacteriophage protein K DUF3610 PF12272.3 ETO32234.1 - 0.029 14.0 5.6 0.036 13.7 3.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3610) DUF1160 PF06648.6 ETO32234.1 - 0.1 12.4 8.6 1.7 8.4 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1160) TetR_C_8 PF14278.1 ETO32234.1 - 3.5 8.0 13.6 4.6 7.6 2.6 3.2 1 1 2 3 3 3 0 Transcriptional regulator C-terminal region Kelch_1 PF01344.20 ETO32236.1 - 1.2e-10 40.7 1.6 0.024 14.1 0.1 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 ETO32236.1 - 4e-08 33.1 1.9 1.1 9.4 0.0 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO32236.1 - 0.00024 20.7 1.1 1.9 8.4 0.0 4.7 4 1 1 5 5 5 1 Kelch motif Kelch_5 PF13854.1 ETO32236.1 - 0.00052 19.9 0.3 6.4 6.8 0.0 4.7 6 0 0 6 6 6 1 Kelch motif Kelch_4 PF13418.1 ETO32236.1 - 0.0013 18.4 0.0 4.2 7.2 0.0 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO32236.1 - 0.018 15.1 0.2 17 5.7 0.0 3.7 4 0 0 4 4 4 0 Galactose oxidase, central domain GF_recep_IV PF14843.1 ETO32236.1 - 1.4 8.5 7.5 0.18 11.4 1.7 2.0 2 0 0 2 2 2 0 Growth factor receptor domain IV PUB PF09409.5 ETO32237.1 - 0.044 13.5 0.4 0.097 12.4 0.3 1.7 1 0 0 1 1 1 0 PUB domain PCI PF01399.22 ETO32237.1 - 0.43 10.9 2.9 2.6 8.3 0.1 2.1 1 1 1 2 2 2 0 PCI domain Sec23_trunk PF04811.10 ETO32240.1 - 3.7e-09 36.2 0.0 4.5e-09 36.0 0.0 1.0 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain VWA_2 PF13519.1 ETO32240.1 - 2.2e-05 24.6 0.1 2.6e-05 24.3 0.1 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain CRA PF06589.6 ETO32242.1 - 0.12 11.7 2.5 0.15 11.3 1.7 1.1 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Chlam_vir PF05475.6 ETO32242.1 - 0.12 11.4 0.4 0.16 11.0 0.3 1.2 1 0 0 1 1 1 0 Chlamydia virulence protein PGP3-D NST1 PF13945.1 ETO32242.1 - 0.2 11.6 3.0 0.22 11.5 2.1 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator WD40 PF00400.27 ETO32243.1 - 1e-13 50.5 0.0 4.2e-09 35.9 0.0 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat Pentapeptide PF00805.17 ETO32243.1 - 4e-06 25.9 3.4 0.0023 17.1 1.1 2.1 1 1 1 2 2 2 2 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO32243.1 - 7.1e-05 22.5 0.2 0.00011 21.8 0.1 1.3 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 ETO32243.1 - 0.00072 19.4 2.5 0.0019 18.0 0.4 2.5 2 1 0 2 2 2 1 Pentapeptide repeats (9 copies) Kinesin PF00225.18 ETO32244.1 - 8.3e-65 218.6 3.6 1.5e-40 138.8 0.1 2.2 1 1 1 2 2 2 2 Kinesin motor domain zf-TRAF PF02176.13 ETO32245.1 - 7.7e-14 51.8 25.3 2.4e-10 40.6 4.6 3.4 2 1 1 3 3 3 3 TRAF-type zinc finger Dapper PF15268.1 ETO32246.1 - 2.5 6.7 13.2 3.4 6.3 9.2 1.2 1 0 0 1 1 1 0 Dapper Utp14 PF04615.8 ETO32246.1 - 9 4.3 45.9 11 4.0 31.8 1.0 1 0 0 1 1 1 0 Utp14 protein cNMP_binding PF00027.24 ETO32248.1 - 4.5e-07 29.5 0.0 1.1e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Orbi_VP5 PF00901.12 ETO32248.1 - 0.0062 14.8 0.1 0.0077 14.4 0.0 1.1 1 0 0 1 1 1 1 Orbivirus outer capsid protein VP5 RPEL PF02755.10 ETO32249.1 - 5.2e-06 25.6 1.5 0.024 13.9 1.2 2.5 2 0 0 2 2 2 2 RPEL repeat CENP-K PF11802.3 ETO32249.1 - 0.25 10.5 8.6 2.4 7.3 2.1 2.2 2 0 0 2 2 2 0 Centromere-associated protein K Suf PF05843.9 ETO32249.1 - 2.5 7.7 10.7 4.6 6.8 7.4 1.4 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) NAF PF03822.9 ETO32249.1 - 5.2 6.8 6.1 49 3.7 0.4 3.3 3 0 0 3 3 3 0 NAF domain SR-25 PF10500.4 ETO32250.1 - 0.005 16.3 4.3 0.012 15.0 3.0 1.6 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Med7 PF05983.6 ETO32252.1 - 0.29 10.8 4.0 2 8.1 0.5 2.5 1 1 1 2 2 2 0 MED7 protein PCI PF01399.22 ETO32253.1 - 9.1e-06 25.9 2.6 0.32 11.3 0.0 3.3 3 0 0 3 3 3 2 PCI domain TPR_2 PF07719.12 ETO32253.1 - 0.13 12.1 0.1 0.35 10.8 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DcpS_C PF11969.3 ETO32254.1 - 0.05 13.8 0.0 0.082 13.1 0.0 1.4 1 1 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Lactamase_B_2 PF12706.2 ETO32255.1 - 1.9e-21 76.4 0.0 3.3e-21 75.7 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 ETO32255.1 - 6.6e-08 32.4 0.3 1.2e-07 31.5 0.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 ETO32255.1 - 0.00013 21.3 0.0 0.00025 20.4 0.0 1.4 1 0 0 1 1 1 1 tRNase Z endonuclease Cu2_monoox_C PF03712.10 ETO32255.1 - 0.042 13.1 0.1 0.081 12.2 0.0 1.4 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Ykof PF07615.6 ETO32259.1 - 0.041 14.0 0.2 0.097 12.8 0.2 1.6 1 1 0 1 1 1 0 YKOF-related Family YcgR_2 PF12945.2 ETO32260.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Flagellar protein YcgR XhlA PF10779.4 ETO32260.1 - 0.14 12.1 1.6 0.16 11.9 0.1 1.8 2 0 0 2 2 2 0 Haemolysin XhlA Macoilin PF09726.4 ETO32260.1 - 3 6.0 21.5 3.5 5.7 14.9 1.2 1 0 0 1 1 1 0 Transmembrane protein SOBP PF15279.1 ETO32260.1 - 3.3 8.0 14.7 4.5 7.5 10.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein TFIIA PF03153.8 ETO32260.1 - 4.2 7.1 17.8 5.3 6.8 12.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit G-alpha PF00503.15 ETO32261.1 - 6.5e-17 61.2 1.5 9.2e-17 60.8 1.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Rad17 PF03215.10 ETO32261.1 - 0.00019 20.2 1.5 0.00096 17.9 0.2 2.0 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein MecA PF05389.7 ETO32261.1 - 0.0041 16.6 1.0 0.0053 16.3 0.7 1.2 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) DUF2834 PF11196.3 ETO32261.1 - 0.013 15.6 0.1 0.025 14.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2834) MtlR PF05068.7 ETO32261.1 - 0.055 12.9 0.2 0.094 12.1 0.2 1.3 1 0 0 1 1 1 0 Mannitol repressor FAM176 PF14851.1 ETO32261.1 - 0.67 9.6 3.7 4.6 6.8 0.7 2.5 3 0 0 3 3 3 0 FAM176 family Pkinase PF00069.20 ETO32262.1 - 3e-43 147.8 0.0 2.2e-40 138.4 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO32262.1 - 1.4e-12 47.2 0.0 3.8e-11 42.5 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase DUF1900 PF08954.6 ETO32262.1 - 0.0061 16.0 0.2 0.014 14.9 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) Peptidase_S49_N PF08496.5 ETO32264.1 - 2.6 7.8 10.7 2.9 7.6 6.4 1.8 2 0 0 2 2 2 0 Peptidase family S49 N-terminal YMF19 PF02326.10 ETO32264.1 - 5.9 7.5 6.1 17 6.0 4.2 1.9 1 1 0 1 1 1 0 Plant ATP synthase F0 NAD_binding_2 PF03446.10 ETO32265.1 - 1.2e-33 116.2 0.1 5.3e-33 114.1 0.0 1.9 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 ETO32265.1 - 1.9e-27 95.7 0.4 1.5e-22 79.9 0.0 2.3 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Ribosomal_L7Ae PF01248.21 ETO32267.1 - 0.012 15.1 0.1 0.64 9.5 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family TP53IP5 PF15331.1 ETO32267.1 - 8 6.3 8.8 0.87 9.4 2.2 2.0 1 1 1 2 2 2 0 Cellular tumour antigen p53-inducible 5 MutS_V PF00488.16 ETO32268.1 - 1.2e-40 139.3 0.4 1.5e-40 139.0 0.3 1.0 1 0 0 1 1 1 1 MutS domain V AAA_29 PF13555.1 ETO32268.1 - 0.0024 17.3 0.0 0.0037 16.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain Synaptonemal_3 PF15191.1 ETO32269.1 - 0.0008 19.0 0.9 0.014 15.1 0.2 2.7 2 1 0 2 2 2 1 Synaptonemal complex central element protein 3 DUF3349 PF11829.3 ETO32269.1 - 0.041 14.2 0.1 2.5 8.6 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3349) CIAPIN1 PF05093.8 ETO32269.1 - 0.044 13.8 0.1 3.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis NLE PF08154.7 ETO32269.1 - 0.092 12.7 0.5 0.68 9.9 0.0 2.2 1 1 1 2 2 2 0 NLE (NUC135) domain PYST-C1 PF09690.5 ETO32269.1 - 0.19 11.4 2.8 0.61 9.7 2.0 1.9 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) WD40 PF00400.27 ETO32271.1 - 3.9e-61 200.9 27.6 4.5e-11 42.1 0.2 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO32271.1 - 5.7e-09 34.6 3.9 0.0033 15.6 0.1 4.6 1 1 3 5 5 5 4 Nucleoporin Nup120/160 DUF2559 PF10832.3 ETO32271.1 - 0.084 12.6 0.2 0.83 9.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2559) Pkinase PF00069.20 ETO32272.1 - 1.8e-30 106.0 0.3 2.7e-29 102.1 0.2 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO32272.1 - 1.1e-14 54.1 0.0 1e-08 34.5 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.18 ETO32272.1 - 0.02 14.6 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-MIZ PF02891.15 ETO32273.1 - 1.6e-14 53.1 1.6 4e-14 51.8 1.1 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger PHD_2 PF13831.1 ETO32273.1 - 0.14 11.4 1.7 1.6 8.1 0.1 2.5 2 0 0 2 2 2 0 PHD-finger Myotub-related PF06602.9 ETO32275.1 - 8.3e-31 107.0 2.1 4.2e-23 81.6 1.5 2.1 1 1 1 2 2 2 2 Myotubularin-like phosphatase domain Menin PF05053.8 ETO32275.1 - 0.87 7.6 6.1 1.3 7.1 4.2 1.4 1 0 0 1 1 1 0 Menin Nucleocapsid-N PF11030.3 ETO32275.1 - 4.2 7.1 17.7 6.4 6.5 12.2 1.3 1 0 0 1 1 1 0 Nucleocapsid protein N DUF3593 PF12159.3 ETO32276.1 - 5.1 6.9 7.6 3 7.6 2.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3593) Borrelia_P83 PF05262.6 ETO32277.1 - 0.00017 20.0 4.0 0.00017 20.0 2.8 2.0 1 1 1 2 2 2 1 Borrelia P83/100 protein INCENP_ARK-bind PF03941.10 ETO32280.1 - 1.8e-08 34.0 0.1 4.8e-08 32.7 0.1 1.8 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region Laminin_G_3 PF13385.1 ETO32281.1 - 2.4e-13 50.6 0.6 8.8e-13 48.7 0.4 2.0 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily TMEM237 PF15383.1 ETO32282.1 - 0.012 14.7 2.8 0.023 13.8 2.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 237 DUF2663 PF10864.3 ETO32282.1 - 4.9 7.3 7.8 4.1 7.6 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) TraT PF05818.7 ETO32283.1 - 0.31 10.4 4.6 17 4.7 3.5 2.2 1 1 1 2 2 2 0 Enterobacterial TraT complement resistance protein Tim44 PF04280.10 ETO32284.1 - 1.6e-15 57.3 0.0 1.9e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Tim44-like domain DUF3291 PF11695.3 ETO32285.1 - 0.021 14.2 0.9 0.034 13.5 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3291) SopA PF13981.1 ETO32286.1 - 0.072 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 SopA-like central domain SH3_1 PF00018.23 ETO32287.1 - 0.083 12.2 0.2 4.7 6.6 0.0 2.7 2 0 0 2 2 2 0 SH3 domain Ribosomal_S4e PF00900.15 ETO32288.1 - 0.17 11.5 1.9 0.29 10.8 1.3 1.6 1 1 0 1 1 1 0 Ribosomal family S4e Spt20 PF12090.3 ETO32290.1 - 1 8.6 7.0 1.2 8.4 4.9 1.0 1 0 0 1 1 1 0 Spt20 family WD40 PF00400.27 ETO32291.1 - 2.3e-17 62.1 0.6 3.8e-06 26.5 0.0 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat PI3_PI4_kinase PF00454.22 ETO32291.1 - 1.1e-10 41.4 7.3 5.7e-05 22.7 0.1 3.1 4 0 0 4 4 4 2 Phosphatidylinositol 3- and 4-kinase Nup160 PF11715.3 ETO32291.1 - 0.0062 14.7 0.1 0.11 10.5 0.0 2.0 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Hph PF13694.1 ETO32291.1 - 0.059 13.3 1.3 0.18 11.8 0.9 1.8 1 0 0 1 1 1 0 Sec63/Sec62 complex-interacting family WD40 PF00400.27 ETO32292.1 - 7.3e-33 111.2 5.6 3.2e-10 39.4 0.1 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO32292.1 - 6.1e-06 24.6 0.5 0.15 10.2 0.0 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO32292.1 - 0.014 15.1 0.8 0.072 12.8 0.1 2.2 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region SH2 PF00017.19 ETO32292.1 - 0.051 13.3 0.1 0.33 10.7 0.0 2.2 1 1 1 2 2 2 0 SH2 domain Skp1 PF01466.14 ETO32293.1 - 0.0096 15.9 0.1 1.2 9.2 0.0 2.4 2 0 0 2 2 2 2 Skp1 family, dimerisation domain zf-TRAF PF02176.13 ETO32294.1 - 5.3e-06 26.7 10.0 1.1e-05 25.7 5.8 2.5 1 1 1 2 2 2 1 TRAF-type zinc finger Band_3_cyto PF07565.8 ETO32294.1 - 0.18 11.2 3.5 0.16 11.4 0.4 1.8 1 1 1 2 2 2 0 Band 3 cytoplasmic domain VWA_2 PF13519.1 ETO32295.1 - 3.6e-15 56.4 0.2 1.1e-12 48.3 0.0 2.3 1 1 1 2 2 2 2 von Willebrand factor type A domain VWA PF00092.23 ETO32295.1 - 6e-05 22.8 0.0 0.00015 21.5 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 ETO32295.1 - 0.0031 17.2 0.2 0.017 14.8 0.2 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain Imm5 PF14423.1 ETO32296.1 - 0.0092 15.6 1.0 0.012 15.2 0.7 1.2 1 0 0 1 1 1 1 Immunity protein Imm5 DUF1257 PF06868.6 ETO32296.1 - 0.053 13.4 3.3 0.14 12.0 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1257) Imm42 PF15601.1 ETO32296.1 - 0.36 10.2 3.3 0.68 9.3 1.5 1.9 1 1 1 2 2 2 0 Immunity protein 42 SPARC_Ca_bdg PF10591.4 ETO32296.1 - 1.2 9.1 6.3 0.33 10.9 1.9 1.8 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region adh_short PF00106.20 ETO32297.1 - 2.3e-16 60.1 0.0 2.1e-06 27.7 0.0 3.2 3 0 0 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.1 ETO32297.1 - 4.4e-07 29.9 0.0 6.9e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETO32297.1 - 0.0023 17.6 0.0 0.01 15.5 0.0 2.0 2 1 0 2 2 2 1 KR domain DUF727 PF05303.7 ETO32297.1 - 0.0039 16.9 0.7 0.28 11.0 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF727) Epimerase PF01370.16 ETO32297.1 - 0.078 12.3 0.2 0.38 10.1 0.2 2.0 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family CcmD PF04995.9 ETO32297.1 - 0.08 12.6 0.1 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Mito_carr PF00153.22 ETO32298.1 - 5.4e-12 45.2 0.1 4.4e-07 29.5 0.0 3.2 2 1 1 3 3 3 2 Mitochondrial carrier protein Alginate_exp PF13372.1 ETO32301.1 - 0.03 12.9 0.0 0.038 12.6 0.0 1.1 1 0 0 1 1 1 0 Alginate export LTV PF04180.9 ETO32301.1 - 0.035 13.6 0.6 0.043 13.3 0.4 1.1 1 0 0 1 1 1 0 Low temperature viability protein Fumble PF03630.9 ETO32301.1 - 0.14 10.9 5.5 0.16 10.7 3.8 1.1 1 0 0 1 1 1 0 Fumble DUF2325 PF10087.4 ETO32301.1 - 0.78 9.6 4.7 5.1 7.0 0.0 2.9 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2325) SAM_1 PF00536.25 ETO32302.1 - 0.0043 17.1 0.1 0.014 15.5 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Menin PF05053.8 ETO32302.1 - 0.045 11.9 2.5 0.052 11.7 1.7 1.1 1 0 0 1 1 1 0 Menin SMI1_KNR4 PF09346.5 ETO32303.1 - 0.094 12.7 0.4 0.11 12.5 0.3 1.2 1 0 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) EFG_IV PF03764.13 ETO32304.1 - 7.7e-21 73.8 0.0 1.2e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 ETO32304.1 - 1.1e-19 70.1 0.0 2e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 ETO32304.1 - 3.3e-07 30.0 0.0 6.2e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 ETO32304.1 - 0.00014 21.9 0.0 0.00068 19.6 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU PF00009.22 ETO32305.1 - 8.1e-21 74.3 0.0 9.9e-21 74.0 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Rad4 PF03835.10 ETO32305.1 - 0.029 13.7 0.1 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain DAHP_synth_1 PF00793.15 ETO32305.1 - 0.16 10.6 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 DAHP synthetase I family Pkinase PF00069.20 ETO32306.1 - 2.1e-44 151.6 0.4 9.6e-44 149.4 0.3 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO32306.1 - 6.8e-33 113.8 0.7 1e-32 113.2 0.5 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase YdfA_immunity PF12127.3 ETO32308.1 - 0.15 10.9 2.5 0.69 8.7 0.0 2.3 2 1 1 3 3 3 0 SigmaW regulon antibacterial Hydrolase_2 PF07486.7 ETO32308.1 - 0.34 11.4 4.2 0.17 12.4 0.5 2.1 1 1 1 2 2 2 0 Cell Wall Hydrolase zf-DHHC PF01529.15 ETO32308.1 - 0.39 10.1 1.9 0.85 8.9 1.3 1.6 1 0 0 1 1 1 0 DHHC palmitoyltransferase SBDS PF01172.13 ETO32309.1 - 5e-18 64.6 0.6 6.2e-18 64.3 0.4 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF3945 PF13101.1 ETO32309.1 - 0.11 11.7 0.3 0.55 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3945) DUF3867 PF12983.2 ETO32309.1 - 0.16 11.9 1.0 0.34 10.8 0.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3867) DUF3816 PF12822.2 ETO32310.1 - 0.012 15.4 7.8 0.7 9.7 2.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3816) Fer4_18 PF13746.1 ETO32310.1 - 0.032 14.6 0.7 2 8.8 0.1 2.9 3 0 0 3 3 3 0 4Fe-4S dicluster domain TPR_12 PF13424.1 ETO32311.1 - 2e-47 159.0 23.8 4.4e-16 58.5 1.5 3.9 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO32311.1 - 2.4e-17 62.3 13.7 6.9e-08 32.0 2.1 3.4 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETO32311.1 - 1.1e-14 53.2 21.4 7.6e-05 22.1 1.0 5.7 5 1 0 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETO32311.1 - 4.4e-14 51.8 0.0 0.00027 20.7 0.0 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO32311.1 - 8.2e-12 43.9 5.8 0.099 12.4 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO32311.1 - 1.9e-10 39.8 17.3 0.00027 20.6 0.6 5.6 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO32311.1 - 1.1e-07 31.0 18.7 0.047 13.4 0.2 5.2 6 0 0 6 6 6 3 Tetratricopeptide repeat SNAP PF14938.1 ETO32311.1 - 1.8e-06 27.3 4.5 2.4e-06 26.8 1.4 1.9 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_6 PF13174.1 ETO32311.1 - 0.019 15.4 7.1 0.14 12.7 0.0 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat MIT PF04212.13 ETO32311.1 - 0.054 13.3 8.7 2.8 7.8 0.1 4.5 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 ETO32311.1 - 0.27 11.3 8.2 0.31 11.1 1.2 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF2225 PF09986.4 ETO32311.1 - 0.43 9.9 7.7 1.7 8.0 1.0 2.5 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-TRAF PF02176.13 ETO32312.1 - 5.1e-05 23.5 0.4 5.1e-05 23.5 0.3 3.1 3 1 1 4 4 4 1 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 ETO32312.1 - 0.023 14.6 1.3 0.23 11.4 0.9 2.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Arena_nucleocap PF00843.12 ETO32312.1 - 0.057 11.2 4.9 0.08 10.8 3.4 1.1 1 0 0 1 1 1 0 Arenavirus nucleocapsid protein GrpE PF01025.14 ETO32312.1 - 5.5 6.5 12.0 2.8 7.4 6.8 1.6 2 0 0 2 2 2 0 GrpE Sulfatase PF00884.18 ETO32313.1 - 1e-07 31.4 0.0 2.5e-06 26.9 0.0 2.6 2 1 0 2 2 2 1 Sulfatase SecE PF00584.15 ETO32313.1 - 0.049 13.2 0.1 0.096 12.2 0.0 1.5 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex DNA_pol_E_B PF04042.11 ETO32314.1 - 1.5e-18 66.8 0.0 1.8e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Es2 PF09751.4 ETO32314.1 - 0.049 13.0 0.0 0.061 12.7 0.0 1.1 1 0 0 1 1 1 0 Nuclear protein Es2 HJURP_C PF12347.3 ETO32315.1 - 0.0011 18.5 0.2 0.0011 18.5 0.2 4.9 5 1 1 6 6 6 1 Holliday junction regulator protein family C-terminal repeat ATG16 PF08614.6 ETO32315.1 - 0.0016 18.3 11.5 0.0016 18.3 8.0 6.3 1 1 4 6 6 6 1 Autophagy protein 16 (ATG16) Filament PF00038.16 ETO32315.1 - 0.091 12.2 130.0 0.014 14.8 8.1 5.8 2 2 2 5 5 5 0 Intermediate filament protein MerR_1 PF13411.1 ETO32317.1 - 0.17 11.6 1.0 46 3.8 0.0 3.5 3 1 1 4 4 4 0 MerR HTH family regulatory protein Cyclin_N PF00134.18 ETO32318.1 - 1e-12 47.7 2.4 3.7e-10 39.4 0.5 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 ETO32318.1 - 2.1e-09 37.3 3.5 2.2e-09 37.2 0.1 2.6 3 0 0 3 3 3 1 Cyclin, C-terminal domain GOLD_2 PF13897.1 ETO32318.1 - 0.043 14.0 0.0 0.098 12.8 0.0 1.6 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking NAD_kinase PF01513.16 ETO32319.1 - 5.3e-12 45.1 0.0 7.1e-12 44.6 0.0 1.3 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 ETO32319.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain NfeD PF01957.13 ETO32320.1 - 0.18 11.9 2.6 0.4 10.8 1.5 1.7 1 1 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF4131 PF13567.1 ETO32320.1 - 2.4 7.5 8.0 1.5 8.1 3.3 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4131) UPF0139 PF03669.8 ETO32321.1 - 0.27 10.7 3.2 1.2 8.7 0.2 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0139) RGS PF00615.14 ETO32322.1 - 0.0049 16.9 1.0 0.035 14.2 0.1 2.3 2 0 0 2 2 2 1 Regulator of G protein signaling domain DUF1206 PF06724.6 ETO32322.1 - 0.022 14.5 0.5 9.7 6.0 0.0 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) RGS PF00615.14 ETO32323.1 - 0.061 13.4 0.3 0.061 13.4 0.2 2.7 2 1 1 3 3 3 0 Regulator of G protein signaling domain YkuD_2 PF13645.1 ETO32324.1 - 0.069 12.3 4.0 0.13 11.5 2.7 1.5 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain Med15 PF09606.5 ETO32324.1 - 0.091 10.9 70.9 0.12 10.5 49.1 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal eIF-3_zeta PF05091.7 ETO32324.1 - 0.15 10.6 17.6 0.19 10.3 12.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Sigma70_r4_2 PF08281.7 ETO32324.1 - 0.18 11.3 3.1 3.9 7.0 0.4 2.5 1 1 1 2 2 2 0 Sigma-70, region 4 Adaptin_binding PF10199.4 ETO32324.1 - 0.28 11.4 16.2 0.055 13.7 8.5 1.9 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 DUF4557 PF15101.1 ETO32324.1 - 0.41 10.4 17.8 0.65 9.7 12.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) FemAB PF02388.11 ETO32324.1 - 0.92 8.1 17.4 1.3 7.6 12.1 1.1 1 0 0 1 1 1 0 FemAB family Dicty_REP PF05086.7 ETO32324.1 - 0.96 7.1 6.8 0.9 7.2 4.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Draxin PF15550.1 ETO32324.1 - 1.7 8.2 14.9 2.4 7.7 10.3 1.2 1 0 0 1 1 1 0 Draxin Peptidase_M1 PF01433.15 ETO32326.1 - 0.018 14.1 0.0 0.037 13.1 0.0 1.5 1 1 0 2 2 2 0 Peptidase family M1 SecIII_SopE_N PF05364.9 ETO32326.1 - 0.066 13.0 0.1 0.28 11.0 0.0 1.9 2 0 0 2 2 2 0 Salmonella type III secretion SopE effector N-terminus Hemerythrin PF01814.18 ETO32328.1 - 0.0021 18.2 9.0 0.0032 17.6 6.2 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain GAS PF13851.1 ETO32328.1 - 0.018 14.2 27.7 0.066 12.4 13.7 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.4 ETO32328.1 - 0.021 14.9 8.8 0.021 14.9 6.1 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.6 ETO32328.1 - 0.17 10.5 22.0 0.32 9.6 14.7 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein PilJ PF13675.1 ETO32328.1 - 0.24 11.7 4.1 0.29 11.4 1.1 2.1 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4164 PF13747.1 ETO32328.1 - 0.36 10.9 18.7 0.096 12.8 4.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) FliD_N PF02465.13 ETO32328.1 - 0.36 11.2 10.7 1 9.7 0.3 2.4 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF3584 PF12128.3 ETO32328.1 - 0.42 7.8 22.3 0.48 7.6 15.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3583 PF12126.3 ETO32328.1 - 0.46 9.5 7.8 0.11 11.4 2.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3583) KR PF08659.5 ETO32328.1 - 1.1 8.9 3.0 1 8.9 0.3 1.9 1 1 0 2 2 2 0 KR domain NPV_P10 PF05531.7 ETO32328.1 - 1.2 9.3 13.0 0.85 9.9 3.2 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein HD_3 PF13023.1 ETO32328.1 - 1.5 8.5 13.0 0.076 12.7 2.1 2.0 1 1 1 2 2 2 0 HD domain CLPTM1 PF05602.7 ETO32328.1 - 4.2 5.9 11.2 5.5 5.5 7.8 1.3 1 1 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) RVT_connect PF06815.8 ETO32328.1 - 4.6 7.1 6.6 1.9 8.4 2.6 1.7 1 1 1 2 2 2 0 Reverse transcriptase connection domain APG6 PF04111.7 ETO32328.1 - 5.2 6.0 25.9 8.4 5.3 17.9 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 Fib_alpha PF08702.5 ETO32328.1 - 6.7 6.8 17.9 4.3 7.4 1.6 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Sigma70_ner PF04546.8 ETO32329.1 - 0.0053 16.4 0.4 0.0081 15.7 0.3 1.3 1 0 0 1 1 1 1 Sigma-70, non-essential region Allexi_40kDa PF05549.6 ETO32329.1 - 0.0069 15.7 0.9 0.0093 15.2 0.1 1.6 2 0 0 2 2 2 1 Allexivirus 40kDa protein LXG PF04740.7 ETO32329.1 - 0.044 13.5 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 LXG domain of WXG superfamily DHC_N1 PF08385.7 ETO32329.1 - 0.052 11.9 0.0 0.067 11.5 0.0 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 DUF515 PF04415.7 ETO32329.1 - 0.33 9.1 2.0 0.54 8.4 1.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF515) O-antigen_lig PF13425.1 ETO32330.1 - 0.013 15.4 0.3 0.03 14.3 0.1 1.7 1 1 0 1 1 1 0 O-antigen ligase like membrane protein DUF3810 PF12725.2 ETO32330.1 - 0.022 13.7 1.4 0.027 13.3 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) YwiC PF14256.1 ETO32330.1 - 0.071 13.1 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 YwiC-like protein YesK PF14150.1 ETO32330.1 - 1.6 8.8 5.3 1.3 9.1 0.9 2.4 2 0 0 2 2 2 0 YesK-like protein Minor_capsid_3 PF12691.2 ETO32331.1 - 0.031 13.9 5.0 0.077 12.6 3.5 1.6 1 0 0 1 1 1 0 Minor capsid protein from bacteriophage Lipoxygenase PF00305.14 ETO32332.1 - 0.00025 19.2 0.1 0.00037 18.6 0.1 1.2 1 0 0 1 1 1 1 Lipoxygenase PBP1_TM PF14812.1 ETO32332.1 - 0.09 13.0 3.5 0.21 11.9 2.4 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 ETO32332.1 - 0.2 11.1 1.9 0.3 10.6 0.6 1.8 2 0 0 2 2 2 0 Nucleoplasmin zf-C2H2_6 PF13912.1 ETO32334.1 - 6.2e-08 32.2 2.2 1.1e-07 31.4 1.5 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 ETO32334.1 - 0.0012 19.0 0.8 0.0031 17.7 0.6 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETO32334.1 - 0.0059 16.8 1.2 0.014 15.6 0.4 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETO32334.1 - 0.0064 16.7 0.7 0.017 15.4 0.5 1.7 1 0 0 1 1 1 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 ETO32334.1 - 0.0066 16.5 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding SNF5 PF04855.7 ETO32334.1 - 0.024 14.0 0.0 0.072 12.5 0.0 1.8 1 0 0 1 1 1 0 SNF5 / SMARCB1 / INI1 zf-C2HC_2 PF13913.1 ETO32334.1 - 0.084 12.5 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Tombus_movement PF05318.7 ETO32335.1 - 3 8.5 8.1 0.64 10.6 2.7 1.9 2 0 0 2 2 2 0 Tombusvirus movement protein B PF02216.11 ETO32336.1 - 0.032 14.0 3.9 0.081 12.6 0.3 2.5 2 0 0 2 2 2 0 B domain zf-RanBP PF00641.13 ETO32337.1 - 7.8e-11 40.8 9.9 4e-08 32.2 0.6 2.8 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.2 ETO32337.1 - 7.9 6.3 11.4 4.1 7.3 0.8 2.7 3 0 0 3 3 3 0 Double zinc ribbon PAP_central PF04928.12 ETO32338.1 - 5.2e-36 123.7 0.7 3.9e-33 114.3 0.4 2.1 2 0 0 2 2 2 2 Poly(A) polymerase central domain NTP_transf_2 PF01909.18 ETO32338.1 - 9e-05 22.7 0.0 0.0002 21.6 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF1097 PF06496.6 ETO32338.1 - 0.023 14.4 0.3 0.046 13.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1097) PAX PF00292.13 ETO32338.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 'Paired box' domain WD40 PF00400.27 ETO32340.1 - 5.4e-13 48.2 7.3 4.7e-07 29.4 0.0 3.7 3 1 0 3 3 3 3 WD domain, G-beta repeat NanE PF04131.9 ETO32341.1 - 0.067 12.1 0.0 0.13 11.2 0.0 1.5 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase YajC PF02699.10 ETO32342.1 - 0.14 11.8 0.4 0.14 11.8 0.3 1.7 1 1 1 2 2 2 0 Preprotein translocase subunit DivIVA PF05103.8 ETO32343.1 - 1.9 8.5 8.2 1.8 8.5 5.7 1.1 1 0 0 1 1 1 0 DivIVA protein SAS4 PF15460.1 ETO32343.1 - 2 8.3 8.8 2.4 8.1 6.1 1.0 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 TSC22 PF01166.13 ETO32343.1 - 3.8 7.5 6.8 4.6 7.2 4.7 1.4 1 1 0 1 1 1 0 TSC-22/dip/bun family Vfa1 PF08432.5 ETO32343.1 - 5.4 7.0 13.4 5.3 7.0 9.3 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 HAP1_N PF04849.8 ETO32343.1 - 6.5 5.6 10.6 6.4 5.6 7.3 1.0 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Ax_dynein_light PF10211.4 ETO32343.1 - 9.9 5.9 10.9 9.9 5.9 7.5 1.0 1 0 0 1 1 1 0 Axonemal dynein light chain NB-ARC PF00931.17 ETO32344.1 - 1.7e-05 23.8 0.7 0.0099 14.7 0.0 2.1 2 0 0 2 2 2 2 NB-ARC domain NACHT PF05729.7 ETO32344.1 - 6.9e-05 22.5 0.0 0.00015 21.4 0.0 1.6 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 ETO32344.1 - 0.00042 20.3 0.0 0.0069 16.3 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain DUF2075 PF09848.4 ETO32344.1 - 0.0012 17.8 0.3 0.075 12.0 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PRK PF00485.13 ETO32344.1 - 0.0068 15.9 0.1 0.25 10.8 0.0 2.1 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.1 ETO32344.1 - 0.018 15.1 1.0 0.4 10.8 0.0 2.1 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.17 ETO32344.1 - 0.027 14.6 0.2 1.6 8.9 0.0 2.5 2 1 0 2 2 2 0 RNA helicase DUF2341 PF10102.4 ETO32344.1 - 0.044 13.9 1.5 0.091 12.9 0.1 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF2341) SMC_N PF02463.14 ETO32344.1 - 0.045 12.9 0.1 0.085 12.0 0.0 1.6 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 ETO32344.1 - 0.056 13.7 1.0 0.56 10.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain Moulting_cycle PF04870.11 ETO32344.1 - 0.083 11.9 3.6 0.12 11.4 2.5 1.2 1 0 0 1 1 1 0 Moulting cycle YtzH PF14165.1 ETO32344.1 - 0.084 13.1 2.8 0.096 12.9 0.7 2.0 1 1 1 2 2 2 0 YtzH-like protein Mg_chelatase PF01078.16 ETO32344.1 - 0.094 11.8 0.0 0.28 10.3 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 ETO32344.1 - 0.096 12.1 0.2 5.2 6.4 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain RCC1 PF00415.13 ETO32346.1 - 1.4e-17 63.6 5.6 2e-07 31.1 0.1 4.3 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO32346.1 - 8.8e-09 34.7 21.8 5e-06 25.9 2.0 3.7 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat DEP PF00610.16 ETO32346.1 - 5.1e-06 26.1 0.0 1.6e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Secretin_N_2 PF07655.8 ETO32346.1 - 0.47 10.8 12.9 1.1 9.7 8.9 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain Paxillin PF03535.8 ETO32347.1 - 0.11 12.2 0.2 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Paxillin family Mucin PF01456.12 ETO32349.1 - 6.2 6.5 7.4 13 5.5 5.1 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein PRMT5 PF05185.11 ETO32351.1 - 4e-120 401.7 0.9 1.9e-71 241.3 0.0 2.2 1 1 1 2 2 2 2 PRMT5 arginine-N-methyltransferase NAD_binding_11 PF14833.1 ETO32354.1 - 1.9e-35 121.6 0.1 7.8e-24 84.0 0.0 2.3 1 1 1 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 ETO32354.1 - 8.1e-24 84.3 0.6 5e-23 81.7 0.4 2.0 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F-box-like PF12937.2 ETO32355.1 - 0.049 13.3 0.2 0.37 10.5 0.0 2.3 2 0 0 2 2 2 0 F-box-like Egg_lysin PF01303.12 ETO32355.1 - 0.068 13.1 0.1 0.18 11.7 0.1 1.7 2 0 0 2 2 2 0 Egg lysin (Sperm-lysin) HSCB_C PF07743.8 ETO32357.1 - 0.025 15.0 1.7 0.12 12.8 0.7 2.5 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain Pep3_Vps18 PF05131.9 ETO32357.1 - 0.036 13.5 0.9 0.086 12.2 0.1 2.1 2 0 0 2 2 2 0 Pep3/Vps18/deep orange family CHAD PF05235.9 ETO32357.1 - 0.12 11.9 0.3 1.3 8.5 0.2 2.0 1 1 0 1 1 1 0 CHAD domain PHD PF00628.24 ETO32358.1 - 4.4e-08 32.6 5.3 1.9e-07 30.6 3.7 2.2 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 ETO32358.1 - 3.2e-06 26.3 8.0 5.3e-06 25.6 2.3 2.4 2 0 0 2 2 2 1 PHD-finger FANCL_C PF11793.3 ETO32358.1 - 0.0035 17.2 2.2 0.0077 16.1 1.5 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain Med15 PF09606.5 ETO32358.1 - 0.66 8.0 31.6 0.68 8.0 21.9 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Kelch_6 PF13964.1 ETO32360.1 - 5.5e-11 42.1 1.2 3.6e-05 23.7 0.0 4.6 3 1 1 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO32360.1 - 2.4e-08 33.6 3.0 2.1e-06 27.3 0.1 3.6 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO32360.1 - 5e-07 29.1 0.1 0.00086 18.8 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 ETO32360.1 - 4.3e-06 26.7 3.5 0.00058 19.9 0.0 4.2 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO32360.1 - 1.6e-05 24.7 1.3 0.38 10.7 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO32360.1 - 0.0041 16.8 5.8 0.4 10.5 0.1 4.0 5 0 0 5 5 5 2 Kelch motif N_Asn_amidohyd PF14736.1 ETO32360.1 - 0.035 12.9 0.1 0.83 8.4 0.0 2.1 2 0 0 2 2 2 0 Protein N-terminal asparagine amidohydrolase Fil_haemagg_2 PF13332.1 ETO32361.1 - 6.6e-12 45.5 82.8 0.00011 22.0 3.1 9.8 3 2 6 10 10 10 7 Haemagluttinin repeat DUF87 PF01935.12 ETO32362.1 - 0.57 9.9 3.3 0.69 9.6 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF87 Med11 PF10280.4 ETO32362.1 - 1.5 8.8 7.2 0.78 9.7 2.6 2.0 2 0 0 2 2 2 0 Mediator complex protein GIDA_assoc_3 PF13932.1 ETO32362.1 - 4.1 7.5 6.8 0.41 10.7 1.6 1.7 2 0 0 2 2 2 0 GidA associated domain 3 AAA_23 PF13476.1 ETO32362.1 - 6 7.1 9.0 7.5 6.8 6.3 1.1 1 0 0 1 1 1 0 AAA domain Peptidase_S49_N PF08496.5 ETO32364.1 - 0.00076 19.3 14.7 0.00086 19.1 10.2 1.0 1 0 0 1 1 1 1 Peptidase family S49 N-terminal Selenoprotein_S PF06936.6 ETO32364.1 - 0.069 12.6 4.8 0.078 12.5 3.3 1.0 1 0 0 1 1 1 0 Selenoprotein S (SelS) EXS PF03124.9 ETO32364.1 - 0.069 12.1 0.0 0.069 12.1 0.0 1.1 1 0 0 1 1 1 0 EXS family KAP PF05804.7 ETO32364.1 - 0.12 10.2 10.3 0.14 10.0 7.1 1.0 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) DUF4446 PF14584.1 ETO32364.1 - 0.18 11.6 5.1 0.2 11.4 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) IncFII_repA PF02387.10 ETO32364.1 - 0.22 10.6 14.6 0.25 10.4 10.1 1.0 1 0 0 1 1 1 0 IncFII RepA protein family CNF1 PF05785.7 ETO32364.1 - 0.37 9.6 4.9 0.43 9.4 3.4 1.1 1 0 0 1 1 1 0 Rho-activating domain of cytotoxic necrotizing factor Sec62 PF03839.11 ETO32364.1 - 0.45 9.8 16.0 0.49 9.7 11.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 OATP PF03137.15 ETO32364.1 - 0.51 8.3 4.2 0.6 8.1 2.9 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Arc_PepC_II PF06847.6 ETO32364.1 - 1.5 9.2 9.6 2.6 8.5 6.6 1.5 1 1 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II ACPS PF01648.15 ETO32365.1 - 9.2e-19 67.3 0.0 1.2e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Glyco_hydro_100 PF12899.2 ETO32365.1 - 0.049 12.0 0.7 0.17 10.2 0.6 1.6 1 1 1 2 2 2 0 Alkaline and neutral invertase DUF1768 PF08719.6 ETO32366.1 - 8.5e-14 51.5 1.1 1.3e-13 51.0 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Na_Ca_ex PF01699.19 ETO32368.1 - 1.6e-25 89.3 36.8 5.7e-17 61.6 7.0 4.0 3 1 0 3 3 3 3 Sodium/calcium exchanger protein Zip PF02535.17 ETO32368.1 - 2.4e-05 23.5 7.1 5.1e-05 22.4 5.0 1.6 1 0 0 1 1 1 1 ZIP Zinc transporter DUF1510 PF07423.6 ETO32368.1 - 0.0093 15.3 0.8 0.0093 15.3 0.6 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) DUF2457 PF10446.4 ETO32368.1 - 0.67 8.6 7.5 0.89 8.2 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BAF1_ABF1 PF04684.8 ETO32368.1 - 1.3 7.7 17.3 1.9 7.2 12.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF912 PF06024.7 ETO32368.1 - 5.7 7.0 5.6 4.3 7.4 0.0 3.3 4 0 0 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CDC45 PF02724.9 ETO32368.1 - 6.2 4.7 8.2 9.5 4.1 5.7 1.2 1 0 0 1 1 1 0 CDC45-like protein SelP_N PF04592.9 ETO32368.1 - 9.7 5.4 17.6 14 4.9 12.2 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region WD40 PF00400.27 ETO32370.1 - 1.9e-18 65.5 0.2 9.1e-08 31.7 0.1 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO32370.1 - 0.0051 15.6 0.2 0.88 8.2 0.0 2.5 2 1 0 3 3 3 2 Nup133 N terminal like tRNA_int_end_N2 PF12928.2 ETO32370.1 - 0.13 11.6 0.0 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 tRNA-splicing endonuclease subunit sen54 N-term His_Phos_1 PF00300.17 ETO32371.1 - 5.3e-14 52.6 0.5 1e-13 51.6 0.3 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 ETO32371.1 - 0.0013 18.1 0.4 0.0019 17.5 0.3 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Mpp10 PF04006.7 ETO32371.1 - 0.093 11.0 0.5 0.13 10.6 0.3 1.1 1 0 0 1 1 1 0 Mpp10 protein TauE PF01925.14 ETO32373.1 - 3.4e-22 79.0 42.6 5.2e-13 49.0 12.2 1.8 1 1 1 2 2 2 2 Sulfite exporter TauE/SafE DUF368 PF04018.8 ETO32373.1 - 0.1 11.7 8.5 0.13 11.4 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF368) EamA PF00892.15 ETO32373.1 - 0.29 11.1 10.6 0.042 13.8 3.6 2.4 2 1 0 2 2 2 0 EamA-like transporter family Transgly_assoc PF04226.8 ETO32373.1 - 5.6 7.1 10.9 3.2 7.9 1.2 3.3 3 1 0 3 3 3 0 Transglycosylase associated protein LINES_N PF14694.1 ETO32374.1 - 9.1e-12 44.8 1.8 9.1e-12 44.8 1.2 2.1 2 0 0 2 2 2 1 Lines N-terminus LINES_C PF14695.1 ETO32374.1 - 5.1e-10 38.4 0.1 1.6e-09 36.8 0.0 1.9 1 0 0 1 1 1 1 Lines C-terminus Nop52 PF05997.7 ETO32374.1 - 0.034 13.5 0.4 0.034 13.5 0.3 2.1 2 0 0 2 2 2 0 Nucleolar protein,Nop52 Na_Ca_ex PF01699.19 ETO32375.1 - 0.0016 18.0 2.0 0.0028 17.2 1.4 1.4 1 0 0 1 1 1 1 Sodium/calcium exchanger protein DUF1673 PF07895.6 ETO32375.1 - 0.0021 17.6 0.4 0.0027 17.2 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1673) Mem_trans PF03547.13 ETO32375.1 - 0.0059 14.9 0.1 0.0068 14.7 0.0 1.1 1 0 0 1 1 1 1 Membrane transport protein DUF4181 PF13789.1 ETO32375.1 - 0.023 14.6 4.1 0.032 14.1 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) Glycophorin_A PF01102.13 ETO32375.1 - 0.054 13.2 0.2 0.33 10.7 0.0 2.0 1 1 1 2 2 2 0 Glycophorin A DUF3592 PF12158.3 ETO32375.1 - 0.08 12.7 0.2 0.16 11.7 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3592) Hid1 PF12722.2 ETO32375.1 - 0.19 9.3 1.6 0.22 9.1 1.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TMEM156 PF15106.1 ETO32375.1 - 1.5 8.0 3.8 1.9 7.6 2.6 1.4 1 1 0 1 1 1 0 TMEM156 protein family GOLD_2 PF13897.1 ETO32375.1 - 1.6 8.9 4.7 0.85 9.8 1.8 1.6 1 1 1 2 2 2 0 Golgi-dynamics membrane-trafficking TMEM151 PF14857.1 ETO32376.1 - 8.1e-13 47.7 0.2 1.1e-12 47.2 0.1 1.1 1 0 0 1 1 1 1 TMEM151 family FixQ PF05545.6 ETO32377.1 - 0.081 12.5 0.9 0.15 11.7 0.6 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Pkinase PF00069.20 ETO32378.1 - 4.3e-60 203.0 10.5 6.3e-57 192.6 0.6 2.8 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO32378.1 - 1.8e-38 132.0 0.1 3.7e-35 121.2 0.1 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Nop14 PF04147.7 ETO32378.1 - 0.00025 19.1 13.9 0.0005 18.1 9.6 1.4 1 0 0 1 1 1 1 Nop14-like family Kinase-like PF14531.1 ETO32378.1 - 0.0028 16.6 0.0 0.0047 15.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETO32378.1 - 0.0089 15.1 0.9 0.018 14.0 0.3 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 ETO32378.1 - 0.018 14.4 0.6 0.018 14.4 0.4 2.0 2 0 0 2 2 2 0 RIO1 family APH PF01636.18 ETO32378.1 - 0.14 11.8 1.0 0.34 10.5 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Anoctamin PF04547.7 ETO32379.1 - 4.5e-45 154.1 0.0 5.2e-45 153.9 0.0 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoctamin PF04547.7 ETO32380.1 - 4.4e-46 157.4 10.3 6.8e-46 156.8 7.1 1.3 1 0 0 1 1 1 1 Calcium-activated chloride channel TB2_DP1_HVA22 PF03134.14 ETO32380.1 - 0.051 13.3 3.0 0.092 12.5 0.1 2.5 2 0 0 2 2 2 0 TB2/DP1, HVA22 family CENP-F_leu_zip PF10473.4 ETO32381.1 - 0.37 10.6 29.8 1.4 8.8 4.5 3.5 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 ETO32381.1 - 1.4 8.0 30.9 1.1 8.4 8.9 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Metal_resist PF13801.1 ETO32381.1 - 3 7.8 7.1 0.81 9.6 0.8 2.1 2 0 0 2 2 2 0 Heavy-metal resistance HAUS-augmin3 PF14932.1 ETO32381.1 - 6.1 5.9 26.0 2.8 7.0 4.6 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Syntaxin-18_N PF10496.4 ETO32382.1 - 0.47 10.3 9.3 0.04 13.7 1.5 3.1 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus TrbI_Ftype PF09677.5 ETO32382.1 - 3.1 7.6 6.4 0.37 10.6 0.8 2.1 2 0 0 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) PseudoU_synth_1 PF01416.15 ETO32383.1 - 3.8e-11 43.3 0.0 9.2e-08 32.4 0.3 2.9 2 1 0 2 2 2 2 tRNA pseudouridine synthase Apis_Csd PF11671.3 ETO32383.1 - 0.76 9.5 22.4 0.073 12.8 11.3 2.4 1 1 0 2 2 2 0 Complementary sex determiner protein YqzH PF14164.1 ETO32383.1 - 0.77 9.7 4.2 17 5.3 0.1 4.1 3 1 1 4 4 4 0 YqzH-like protein PCMT PF01135.14 ETO32385.1 - 0.075 12.5 0.1 0.14 11.6 0.0 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Helicase_Sgs1 PF11408.3 ETO32385.1 - 1.6 8.5 5.4 3 7.7 3.6 1.5 1 1 0 1 1 1 0 Sgs1 RecQ helicase WD40 PF00400.27 ETO32388.1 - 7.5e-44 146.0 16.9 4.1e-13 48.6 0.0 8.8 10 0 0 10 10 10 6 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO32388.1 - 1e-06 28.6 0.7 0.0022 18.0 0.1 4.0 3 0 0 3 3 3 1 Kelch motif Cytochrom_D1 PF02239.11 ETO32388.1 - 2.7e-06 25.9 0.1 0.0024 16.2 0.1 3.7 2 1 0 2 2 2 1 Cytochrome D1 heme domain PD40 PF07676.7 ETO32388.1 - 1.3e-05 24.7 1.4 7.1 6.4 0.0 6.0 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Kelch_1 PF01344.20 ETO32388.1 - 5.6e-05 22.5 0.2 5.6e-05 22.5 0.1 2.4 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETO32388.1 - 0.00016 21.3 0.1 0.0018 17.9 0.1 2.5 2 0 0 2 2 2 1 Galactose oxidase, central domain Gmad1 PF10647.4 ETO32388.1 - 0.51 9.6 0.0 15 4.8 0.0 2.5 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain Proteasome_A_N PF10584.4 ETO32388.1 - 0.54 9.6 8.3 40 3.6 0.2 4.6 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature RXT2_N PF08595.6 ETO32390.1 - 0.0044 16.8 7.5 0.0057 16.4 5.2 1.1 1 0 0 1 1 1 1 RXT2-like, N-terminal DUF1510 PF07423.6 ETO32390.1 - 0.019 14.3 9.4 0.026 13.9 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pox_Ag35 PF03286.9 ETO32390.1 - 0.035 13.6 7.8 0.048 13.1 5.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nucleoside_tran PF01733.13 ETO32390.1 - 0.041 13.0 0.4 0.054 12.6 0.3 1.2 1 0 0 1 1 1 0 Nucleoside transporter ORC6 PF05460.8 ETO32390.1 - 0.043 12.9 3.2 0.055 12.5 2.2 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Vfa1 PF08432.5 ETO32390.1 - 0.045 13.7 7.1 0.061 13.3 4.9 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2457 PF10446.4 ETO32390.1 - 0.093 11.4 11.0 0.12 11.0 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Urb2 PF10441.4 ETO32390.1 - 0.13 11.8 0.9 0.82 9.2 0.1 2.1 2 0 0 2 2 2 0 Urb2/Npa2 family DUF822 PF05687.8 ETO32390.1 - 0.16 12.3 2.5 0.17 12.2 1.1 1.4 1 1 0 1 1 1 0 Plant protein of unknown function (DUF822) Myc_N PF01056.13 ETO32390.1 - 0.45 9.6 5.9 0.53 9.3 4.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Astro_capsid PF03115.9 ETO32390.1 - 0.56 8.4 5.5 0.63 8.2 3.8 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor CDC45 PF02724.9 ETO32390.1 - 0.7 7.8 6.7 0.76 7.7 4.7 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 ETO32390.1 - 2.6 7.2 7.9 3.6 6.7 5.5 1.2 1 0 0 1 1 1 0 NOA36 protein Paramyxo_ncap PF00973.14 ETO32390.1 - 2.7 6.5 5.8 2.9 6.4 4.0 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CENP-B_dimeris PF09026.5 ETO32390.1 - 4.1 7.6 13.8 9 6.6 9.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.7 ETO32390.1 - 4.8 6.8 18.0 6.5 6.3 12.5 1.3 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF641 PF04859.7 ETO32391.1 - 0.088 12.5 13.2 0.16 11.7 9.1 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF812 PF05667.6 ETO32391.1 - 0.26 9.7 16.5 0.39 9.1 11.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) LMBR1 PF04791.11 ETO32391.1 - 0.39 9.2 3.1 0.39 9.2 2.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Tropomyosin PF00261.15 ETO32391.1 - 1 8.4 19.8 1.5 7.8 13.7 1.1 1 0 0 1 1 1 0 Tropomyosin AAA_13 PF13166.1 ETO32391.1 - 2.6 6.4 15.2 3.4 6.0 10.5 1.2 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 ETO32392.1 - 2.3e-61 201.6 27.9 1.4e-10 40.6 1.1 7.0 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO32392.1 - 4.4e-08 31.7 8.4 0.077 11.1 0.1 5.8 2 1 2 5 5 5 5 Nucleoporin Nup120/160 Metallophos PF00149.23 ETO32393.1 - 3.2e-28 98.5 0.0 4e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Flavoprotein PF02441.14 ETO32394.1 - 6.5e-34 116.3 1.7 7.8e-30 103.1 0.0 2.6 2 1 1 3 3 3 2 Flavoprotein CAP_GLY PF01302.20 ETO32395.1 - 5.5e-29 99.6 11.6 1.1e-11 44.2 0.1 3.3 3 0 0 3 3 3 3 CAP-Gly domain YajC PF02699.10 ETO32395.1 - 0.12 12.0 0.3 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 Preprotein translocase subunit CAP_GLY PF01302.20 ETO32396.1 - 1.9e-18 65.8 1.9 2.4e-18 65.5 0.2 2.0 2 0 0 2 2 2 1 CAP-Gly domain RPEL PF02755.10 ETO32396.1 - 1.1e-06 27.7 0.4 9.2e-06 24.8 0.1 2.3 2 0 0 2 2 2 1 RPEL repeat Mucin PF01456.12 ETO32397.1 - 1.2 8.9 35.5 0.054 13.2 19.6 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein VWA_2 PF13519.1 ETO32398.1 - 2.3e-09 37.5 0.0 3.7e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Helicase_C PF00271.26 ETO32398.1 - 9.1e-05 22.2 0.3 0.0046 16.7 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Peptidase_C14 PF00656.17 ETO32399.1 - 3.3e-07 30.2 0.2 5e-07 29.6 0.1 1.3 1 1 0 1 1 1 1 Caspase domain Ret_tiss PF10044.4 ETO32400.1 - 0.0061 17.0 3.6 2.7 8.5 0.0 3.9 3 2 0 3 3 3 3 Retinal tissue protein TAF PF02969.12 ETO32402.1 - 1.1e-07 31.7 0.3 3.5e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Ras PF00071.17 ETO32403.1 - 1.3e-45 154.7 0.1 3.5e-45 153.3 0.1 1.7 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO32403.1 - 1.2e-10 41.8 0.0 6e-10 39.6 0.0 2.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 ETO32403.1 - 7.3e-06 25.5 0.1 2.7e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.16 ETO32403.1 - 2e-05 23.9 1.0 2e-05 23.9 0.7 2.2 1 1 1 2 2 2 1 ADP-ribosylation factor family ROF PF07073.7 ETO32404.1 - 0.055 13.4 1.1 0.19 11.7 0.2 2.3 2 0 0 2 2 2 0 Modulator of Rho-dependent transcription termination (ROF) PABP PF00658.13 ETO32405.1 - 6.2e-07 28.9 0.0 1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain DUF3439 PF11921.3 ETO32405.1 - 9.4 6.0 14.7 9.1 6.0 9.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3439) RRM_1 PF00076.17 ETO32406.1 - 7.6e-16 57.5 0.1 1.7e-06 27.5 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO32406.1 - 1.7e-10 40.6 0.1 2.6e-05 24.0 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETO32406.1 - 6.9e-07 28.9 0.0 0.00059 19.5 0.0 2.8 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 ETO32406.1 - 0.00018 21.2 0.7 0.52 10.2 0.1 3.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phospholip_A2_3 PF09056.6 ETO32406.1 - 0.0099 16.0 0.3 0.035 14.3 0.2 2.0 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 GFA PF04828.9 ETO32406.1 - 0.19 11.7 2.1 0.31 11.0 0.3 2.2 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Pribosyltran PF00156.22 ETO32407.1 - 9e-08 31.8 0.0 1.5e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.1 ETO32407.1 - 1.5e-05 24.8 0.0 1.8e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Nuc-transf PF10127.4 ETO32409.1 - 0.11 11.8 0.1 0.13 11.5 0.0 1.0 1 0 0 1 1 1 0 Predicted nucleotidyltransferase Nucleoplasmin PF03066.10 ETO32412.1 - 1.6 8.2 15.6 0.12 11.8 4.6 2.5 2 0 0 2 2 2 0 Nucleoplasmin CENP-B_dimeris PF09026.5 ETO32412.1 - 3 8.1 17.0 0.49 10.6 3.5 3.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Vps26 PF03643.10 ETO32414.1 - 4.3e-104 347.1 2.3 5e-104 346.9 1.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 SAGA-Tad1 PF12767.2 ETO32415.1 - 0.16 11.6 6.7 0.2 11.3 4.7 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF3752 PF12572.3 ETO32415.1 - 0.37 10.8 5.2 0.56 10.3 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) DUF966 PF06136.8 ETO32415.1 - 0.6 9.4 9.1 0.72 9.2 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Paramyxo_C PF01692.13 ETO32415.1 - 1.3 8.6 9.8 33 4.0 6.8 2.3 2 0 0 2 2 2 0 Paramyxovirus non-structural protein c SAYSvFN PF10260.4 ETO32416.1 - 1.1e-20 73.1 2.5 1.9e-20 72.3 1.8 1.4 1 0 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) SEC-C PF02810.10 ETO32416.1 - 3.1e-05 23.3 9.9 4.8e-05 22.7 6.9 1.3 1 0 0 1 1 1 1 SEC-C motif DUF2804 PF10974.3 ETO32416.1 - 0.015 14.1 0.1 0.02 13.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2804) HNF-1A_C PF04813.7 ETO32418.1 - 0.17 12.1 4.3 0.088 13.0 1.1 1.8 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus ATP-synt_ab PF00006.20 ETO32419.1 - 1.1e-06 28.3 0.1 1.5e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Rtf2 PF04641.7 ETO32419.1 - 0.046 12.9 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger SNARE_assoc PF09335.6 ETO32420.1 - 0.0016 18.6 0.9 0.0016 18.6 0.6 2.9 3 0 0 3 3 3 1 SNARE associated Golgi protein ATP-synt_ab PF00006.20 ETO32421.1 - 7.8e-42 143.2 0.0 8.2e-41 139.8 0.0 2.0 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 ETO32421.1 - 1.3e-11 44.9 0.0 2.1e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain zf-C2H2_4 PF13894.1 ETO32422.1 - 1.4e-08 34.4 18.7 0.0043 17.2 0.4 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 ETO32422.1 - 1.6e-07 31.2 26.1 0.00027 21.0 0.8 4.1 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETO32422.1 - 5.8e-05 23.1 16.2 0.00047 20.3 0.1 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 ETO32422.1 - 0.0016 18.4 12.6 0.093 12.9 0.0 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 ETO32422.1 - 0.0017 18.5 14.3 0.0058 16.7 0.1 3.6 3 0 0 3 3 3 1 Zinc-finger of C2H2 type DUF1777 PF08648.7 ETO32422.1 - 0.0027 17.4 28.8 0.005 16.5 20.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) zf-C2H2_2 PF12756.2 ETO32422.1 - 0.0066 16.5 12.4 0.058 13.5 0.1 3.3 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) Corona_nucleoca PF00937.13 ETO32422.1 - 0.0091 14.9 21.9 0.014 14.3 15.2 1.2 1 0 0 1 1 1 1 Coronavirus nucleocapsid protein zf-C2H2_6 PF13912.1 ETO32422.1 - 0.046 13.6 15.7 0.16 11.8 0.2 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger XAP5 PF04921.9 ETO32422.1 - 0.052 13.0 5.2 0.088 12.3 3.6 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator DUF1509 PF07420.6 ETO32422.1 - 0.095 11.9 17.0 0.17 11.1 11.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) zf-met2 PF12907.2 ETO32422.1 - 0.29 11.1 4.5 0.44 10.5 0.4 2.5 2 0 0 2 2 2 0 Zinc-binding MIP-T3 PF10243.4 ETO32422.1 - 0.88 7.9 18.9 1.2 7.4 13.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DZR PF12773.2 ETO32422.1 - 1.2 8.9 5.3 1 9.2 1.5 2.5 2 1 1 3 3 3 0 Double zinc ribbon PyrI_C PF02748.10 ETO32422.1 - 6.8 6.2 8.5 0.27 10.6 0.1 2.9 3 1 1 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain PHD PF00628.24 ETO32422.1 - 6.9 6.4 9.6 2.3 7.9 2.1 2.6 2 0 0 2 2 2 0 PHD-finger DDHD PF02862.12 ETO32422.1 - 7.6 6.2 10.3 1.4 8.6 3.0 2.2 2 0 0 2 2 2 0 DDHD domain FixP_N PF14715.1 ETO32423.1 - 2.1 7.8 4.1 4.9 6.6 2.8 1.7 1 1 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP fn3 PF00041.16 ETO32424.1 - 0.0065 16.5 0.4 0.077 13.1 0.0 2.3 2 0 0 2 2 2 1 Fibronectin type III domain Thioredoxin_2 PF13098.1 ETO32424.1 - 0.019 15.1 0.1 0.044 13.9 0.1 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain PUB PF09409.5 ETO32425.1 - 0.057 13.1 5.7 0.14 11.8 2.4 2.6 1 1 1 2 2 2 0 PUB domain Flp_N PF03930.9 ETO32425.1 - 0.074 12.8 0.9 0.074 12.8 0.6 2.6 2 1 1 3 3 3 0 Recombinase Flp protein N-terminus WD40 PF00400.27 ETO32426.1 - 1.2e-59 196.2 22.5 1.9e-10 40.2 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO32426.1 - 2.8e-14 52.1 6.0 7e-05 21.1 0.0 5.2 2 1 3 5 5 5 5 Nucleoporin Nup120/160 EamA PF00892.15 ETO32427.1 - 2.1e-05 24.5 26.7 0.00083 19.3 0.7 4.4 4 1 0 4 4 4 2 EamA-like transporter family Kelch_2 PF07646.10 ETO32428.1 - 0.0012 18.5 1.4 9.8 6.1 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO32428.1 - 0.0043 17.1 3.0 2.2 8.5 0.1 4.2 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO32428.1 - 0.098 12.2 6.3 0.77 9.3 0.5 4.0 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.10 ETO32429.1 - 0.0018 17.9 0.1 1.8 8.4 0.1 3.9 4 0 0 4 4 4 2 Kelch motif PUB PF09409.5 ETO32430.1 - 6.5e-05 22.6 0.0 0.00019 21.1 0.0 1.8 1 0 0 1 1 1 1 PUB domain ATP11 PF06644.6 ETO32430.1 - 0.58 9.6 7.2 0.86 9.0 5.0 1.4 1 0 0 1 1 1 0 ATP11 protein Topoisom_I_N PF02919.10 ETO32430.1 - 2.6 7.2 10.4 0.19 11.0 3.9 1.5 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment MscS_TM PF12794.2 ETO32430.1 - 2.9 6.4 4.6 4.6 5.7 3.2 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF106 PF01956.11 ETO32430.1 - 3.1 7.3 4.5 5.2 6.5 3.1 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF106 MAT1 PF06391.8 ETO32430.1 - 6.1 6.3 17.1 1.8 8.0 9.7 1.6 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Pkinase PF00069.20 ETO32431.1 - 3.1e-45 154.3 0.0 9.5e-45 152.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO32431.1 - 2.1e-16 59.7 0.0 8.6e-16 57.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO32431.1 - 0.00022 20.2 0.0 0.00037 19.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF3853 PF12964.2 ETO32432.1 - 0.031 14.0 0.7 0.17 11.7 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3853) RasGEF_N PF00618.15 ETO32432.1 - 0.1 12.7 2.8 0.41 10.7 1.7 2.1 1 1 1 2 2 2 0 RasGEF N-terminal motif YlbD_coat PF14071.1 ETO32432.1 - 0.37 10.8 7.1 0.11 12.5 2.7 1.8 2 0 0 2 2 2 0 Putative coat protein PMC2NT PF08066.7 ETO32432.1 - 2.1 8.6 7.8 6 7.2 0.1 2.9 4 0 0 4 4 4 0 PMC2NT (NUC016) domain KMP11 PF03037.11 ETO32432.1 - 3.1 8.4 8.2 5 7.7 0.4 2.8 2 1 0 2 2 2 0 Kinetoplastid membrane protein 11 AstE_AspA PF04952.9 ETO32433.1 - 2.8e-43 147.8 0.0 4.1e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family SPX PF03105.14 ETO32433.1 - 0.0001 22.1 21.8 0.0011 18.7 12.7 2.9 2 1 0 2 2 2 1 SPX domain TMF_DNA_bd PF12329.3 ETO32433.1 - 0.0009 19.0 2.6 0.0067 16.2 0.7 2.8 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding Peptidase_M14 PF00246.19 ETO32433.1 - 0.0076 15.8 0.0 0.074 12.6 0.0 2.3 2 0 0 2 2 2 1 Zinc carboxypeptidase BLOC1_2 PF10046.4 ETO32433.1 - 1.8 8.7 8.4 0.47 10.6 0.2 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Draxin PF15550.1 ETO32433.1 - 4.7 6.7 6.9 0.96 9.0 2.4 1.5 2 0 0 2 2 2 0 Draxin NACHT PF05729.7 ETO32434.1 - 1.9e-08 34.1 0.0 6.8e-08 32.3 0.0 1.9 2 1 0 2 2 2 1 NACHT domain NB-ARC PF00931.17 ETO32434.1 - 1.6e-06 27.2 0.0 3.4e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 ETO32434.1 - 0.0022 18.1 0.1 0.007 16.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETO32434.1 - 0.0067 16.4 0.4 0.14 12.1 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain AAA PF00004.24 ETO32434.1 - 0.0075 16.4 0.0 0.027 14.6 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 ETO32434.1 - 0.0079 15.6 0.1 3.5 7.0 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein KAP_NTPase PF07693.9 ETO32434.1 - 0.011 14.7 0.0 0.023 13.6 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain Ribosomal_60s PF00428.14 ETO32434.1 - 0.023 15.0 3.0 0.023 15.0 2.0 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein OTCace_N PF02729.16 ETO32434.1 - 0.034 13.8 0.0 0.079 12.6 0.0 1.6 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Daxx PF03344.10 ETO32434.1 - 6.4 5.1 22.1 10 4.4 15.3 1.2 1 0 0 1 1 1 0 Daxx Family PDEase_I PF00233.14 ETO32435.1 - 2.2e-48 165.0 4.6 6e-48 163.6 3.2 1.7 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.21 ETO32435.1 - 8.2e-19 68.2 1.1 1.1e-08 35.3 0.0 4.4 3 2 0 3 3 3 3 GAF domain GAF_3 PF13492.1 ETO32435.1 - 1.1e-17 64.2 0.4 4.6e-08 33.2 0.0 4.3 3 1 0 3 3 3 3 GAF domain GAF_2 PF13185.1 ETO32435.1 - 3.2e-15 56.9 0.1 1e-06 29.2 0.0 3.9 4 0 0 4 4 4 3 GAF domain HD PF01966.17 ETO32435.1 - 0.022 14.7 0.1 0.084 12.8 0.1 2.0 1 0 0 1 1 1 0 HD domain PT PF04886.7 ETO32436.1 - 7.4e-15 53.9 208.7 38 3.7 22.6 9.1 1 1 3 4 4 4 1 PT repeat DUF912 PF06024.7 ETO32436.1 - 0.027 14.5 0.2 0.071 13.1 0.1 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Rifin_STEVOR PF02009.11 ETO32436.1 - 0.1 12.2 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family DUF2946 PF11162.3 ETO32437.1 - 4.6 7.4 6.5 12 6.0 4.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) WD40 PF00400.27 ETO32438.1 - 1.2e-28 97.9 35.3 3.6e-11 42.4 0.1 6.2 6 1 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO32438.1 - 5e-05 21.6 2.6 0.21 9.6 0.3 3.3 1 1 2 4 4 4 3 Nucleoporin Nup120/160 DUF3300 PF11737.3 ETO32438.1 - 1.7 7.8 4.3 2.8 7.1 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3300) TPR_12 PF13424.1 ETO32439.1 - 4.8e-59 196.2 16.4 5e-20 71.2 0.4 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO32439.1 - 8.6e-31 103.2 14.1 9.9e-05 21.8 0.0 7.1 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.1 ETO32439.1 - 9.5e-31 105.2 35.9 1.1e-11 44.1 0.8 5.3 3 1 3 6 6 6 5 TPR repeat TPR_10 PF13374.1 ETO32439.1 - 5.7e-29 99.1 0.0 0.00088 19.1 0.0 6.6 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETO32439.1 - 1.5e-28 97.2 38.1 1.3e-05 24.5 0.0 7.9 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.12 ETO32439.1 - 4.6e-26 88.5 29.9 0.00027 20.6 0.0 8.0 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETO32439.1 - 7.5e-19 66.0 45.8 0.00047 19.7 0.4 8.1 9 1 0 9 9 8 6 Tetratricopeptide repeat TPR_17 PF13431.1 ETO32439.1 - 2.3e-12 46.0 4.7 0.38 11.0 0.0 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO32439.1 - 3.8e-10 40.1 0.0 0.096 13.3 0.1 5.1 3 2 1 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO32439.1 - 7.9e-08 32.2 0.0 23 5.9 0.0 6.3 6 1 1 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO32439.1 - 1.7e-06 28.1 2.9 12 6.5 0.0 6.5 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETO32439.1 - 6.4e-06 26.4 3.6 0.83 10.0 0.0 5.2 4 1 2 6 6 6 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO32439.1 - 8.1e-06 24.9 9.9 0.19 11.0 0.2 5.0 5 0 0 5 5 5 2 SHNi-TPR DUF3568 PF12092.3 ETO32439.1 - 0.00053 19.7 0.9 14 5.4 0.0 4.3 1 1 1 4 4 4 0 Protein of unknown function (DUF3568) Ten1_2 PF15490.1 ETO32439.1 - 0.0014 18.2 0.3 14 5.2 0.0 4.2 1 1 4 5 5 5 0 Telomere-capping, CST complex subunit DUF627 PF04781.7 ETO32439.1 - 0.0081 15.7 9.5 4.9 6.8 0.2 5.2 4 2 2 6 6 6 1 Protein of unknown function (DUF627) Ten1 PF12658.2 ETO32439.1 - 0.091 12.5 0.0 1.7 8.4 0.0 2.2 1 1 0 1 1 1 0 Telomere capping, CST complex subunit Phage_Treg PF04761.7 ETO32439.1 - 5.5 6.8 12.0 0.92 9.3 0.2 4.2 5 0 0 5 5 5 0 Lactococcus bacteriophage putative transcription regulator TPR_12 PF13424.1 ETO32440.1 - 1.1e-77 256.0 16.7 6e-18 64.5 0.9 5.7 3 1 2 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETO32440.1 - 1.1e-39 132.3 37.1 2.7e-05 23.5 2.5 10.3 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_11 PF13414.1 ETO32440.1 - 2.6e-39 132.7 22.7 4.1e-10 39.1 1.9 6.4 1 1 4 7 7 7 7 TPR repeat TPR_2 PF07719.12 ETO32440.1 - 1.1e-36 121.7 28.6 0.00011 21.8 0.0 10.1 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_7 PF13176.1 ETO32440.1 - 2e-35 117.7 13.1 0.00079 19.0 0.0 9.0 9 0 0 9 9 8 8 Tetratricopeptide repeat TPR_10 PF13374.1 ETO32440.1 - 1.4e-31 107.4 0.0 0.0017 18.2 0.0 9.3 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETO32440.1 - 2.3e-29 98.9 42.3 0.00078 19.0 0.1 9.7 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_16 PF13432.1 ETO32440.1 - 9.7e-18 64.3 0.0 0.012 16.2 0.0 7.0 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETO32440.1 - 2.9e-16 58.2 5.6 0.35 11.1 0.0 9.1 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO32440.1 - 1.2e-11 44.1 0.0 6.9 7.6 0.0 8.4 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO32440.1 - 2.4e-09 37.0 7.6 10 6.8 0.0 8.1 9 0 0 9 9 6 0 Tetratricopeptide repeat Peptidase_C14 PF00656.17 ETO32440.1 - 7.8e-09 35.5 0.5 1.6e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 Caspase domain TPR_19 PF14559.1 ETO32440.1 - 8.4e-09 35.6 5.8 0.39 11.0 0.2 6.6 4 2 2 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 ETO32440.1 - 1.3e-07 31.6 22.7 0.07 13.2 5.0 6.2 1 1 5 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 ETO32440.1 - 2e-05 24.3 22.3 0.85 9.5 0.0 8.2 8 0 0 8 8 8 2 MIT (microtubule interacting and transport) domain DUF3856 PF12968.2 ETO32440.1 - 0.00031 20.5 5.3 0.1 12.4 0.7 4.2 3 3 1 4 4 4 1 Domain of Unknown Function (DUF3856) DUF627 PF04781.7 ETO32440.1 - 0.00069 19.2 9.2 2.1 7.9 0.0 5.5 5 2 1 6 6 6 1 Protein of unknown function (DUF627) TPR_21 PF09976.4 ETO32440.1 - 0.0014 18.6 0.7 0.18 11.7 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF1955 PF09205.5 ETO32440.1 - 0.0077 15.7 1.8 1.1 8.7 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1955) DUF3568 PF12092.3 ETO32440.1 - 0.014 15.1 0.4 2.3 7.9 0.0 4.2 3 1 2 5 5 5 0 Protein of unknown function (DUF3568) Ten1_2 PF15490.1 ETO32440.1 - 0.015 14.9 0.0 9.2 5.8 0.0 4.0 3 2 1 4 4 4 0 Telomere-capping, CST complex subunit SHNi-TPR PF10516.4 ETO32440.1 - 0.062 12.5 0.1 0.062 12.5 0.1 4.8 6 0 0 6 6 6 0 SHNi-TPR Mob_Pre PF01076.14 ETO32440.1 - 0.32 10.5 16.0 0.77 9.3 0.5 4.1 3 1 1 4 4 4 0 Plasmid recombination enzyme TPR_3 PF07720.7 ETO32440.1 - 5 7.0 17.0 6.3 6.7 1.4 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat WD40 PF00400.27 ETO32443.1 - 3.8e-58 191.4 23.4 3.8e-11 42.4 0.3 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO32443.1 - 7.6e-11 40.8 6.1 0.0056 14.8 0.0 5.4 2 2 3 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO32443.1 - 0.014 14.2 10.7 0.31 9.7 0.0 3.6 2 1 2 4 4 4 0 Nup133 N terminal like Thermopsin PF05317.6 ETO32444.1 - 0.018 13.9 0.6 0.018 13.9 0.4 1.9 1 1 0 2 2 2 0 Thermopsin OTU PF02338.14 ETO32445.1 - 9e-13 48.8 0.2 4.9e-12 46.5 0.0 2.2 3 0 0 3 3 3 1 OTU-like cysteine protease zf-C2H2_2 PF12756.2 ETO32445.1 - 0.007 16.4 0.6 0.056 13.5 0.1 2.4 3 0 0 3 3 3 1 C2H2 type zinc-finger (2 copies) BAG PF02179.11 ETO32445.1 - 0.085 12.9 1.7 0.1 12.7 0.1 1.9 2 0 0 2 2 2 0 BAG domain zf-met PF12874.2 ETO32445.1 - 0.11 12.6 0.4 0.29 11.3 0.3 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DUF678 PF05077.7 ETO32445.1 - 0.19 11.7 1.1 4 7.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF678) Pkinase PF00069.20 ETO32446.1 - 3.8e-44 150.7 0.0 7.3e-44 149.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO32446.1 - 1.4e-29 102.9 0.0 1.9e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO32446.1 - 2.7e-05 23.2 0.0 4.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 ETO32446.1 - 0.0024 16.7 0.2 0.036 12.9 0.0 2.4 3 0 0 3 3 3 1 Seadornavirus VP7 APH PF01636.18 ETO32446.1 - 0.011 15.5 0.1 0.025 14.3 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 ETO32446.1 - 0.027 13.2 0.0 0.04 12.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PIG-P PF08510.7 ETO32447.1 - 0.16 11.5 0.1 0.16 11.5 0.1 3.4 2 1 1 3 3 3 0 PIG-P DUF912 PF06024.7 ETO32447.1 - 1.8 8.6 0.0 1.8 8.6 0.0 5.3 6 1 0 6 6 6 0 Nucleopolyhedrovirus protein of unknown function (DUF912) JmjC PF02373.17 ETO32448.1 - 4.9e-34 116.9 2.6 1.1e-32 112.6 0.1 2.5 3 0 0 3 3 3 2 JmjC domain, hydroxylase PLU-1 PF08429.6 ETO32449.1 - 6.4e-08 31.8 15.4 2e-05 23.6 2.6 3.2 2 1 1 3 3 3 3 PLU-1-like protein DUF1510 PF07423.6 ETO32450.1 - 0.015 14.7 25.7 0.069 12.5 8.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Gti1_Pac2 PF09729.4 ETO32450.1 - 1.6 8.5 14.2 4.9 6.9 1.3 2.6 2 0 0 2 2 2 0 Gti1/Pac2 family Ctr PF04145.10 ETO32450.1 - 5.8 6.9 5.4 25 4.8 1.0 2.5 2 0 0 2 2 2 0 Ctr copper transporter family Adaptin_N PF01602.15 ETO32451.1 - 3.1e-23 81.9 0.8 3.7e-23 81.6 0.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region NARP1 PF12569.3 ETO32451.1 - 7.5 5.1 9.4 12 4.5 6.5 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Pex14_N PF04695.8 ETO32453.1 - 0.026 14.5 0.7 0.036 14.1 0.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Tim54 PF11711.3 ETO32453.1 - 1.4 7.4 7.0 1.7 7.1 4.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Trypan_PARP PF05887.6 ETO32453.1 - 2.4 7.9 14.4 3.2 7.5 10.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF1275 PF06912.6 ETO32454.1 - 0.42 9.7 8.9 1.4 8.0 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1275) NACHT PF05729.7 ETO32456.1 - 5.6e-10 39.1 0.0 1.1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO32456.1 - 1.3e-05 25.5 0.3 0.0011 19.2 0.1 2.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETO32456.1 - 2e-05 24.7 0.1 0.00044 20.3 0.0 2.7 3 0 0 3 3 3 1 AAA domain RelA_SpoT PF04607.12 ETO32456.1 - 3.6e-05 23.7 0.2 3.6e-05 23.7 0.1 2.4 3 0 0 3 3 3 1 Region found in RelA / SpoT proteins AAA_17 PF13207.1 ETO32456.1 - 0.0038 18.0 0.2 0.11 13.3 0.0 3.0 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 ETO32456.1 - 0.0093 16.1 1.1 0.13 12.4 0.0 2.9 2 1 0 2 2 2 1 RNA helicase ATP_bind_2 PF03668.10 ETO32456.1 - 0.017 14.2 0.0 0.11 11.5 0.0 2.1 2 0 0 2 2 2 0 P-loop ATPase protein family UPF0079 PF02367.12 ETO32456.1 - 0.02 14.5 0.0 0.084 12.5 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SapC PF07277.6 ETO32456.1 - 0.025 13.8 0.4 4.6 6.4 0.0 2.8 3 0 0 3 3 3 0 SapC AAA_16 PF13191.1 ETO32456.1 - 0.031 14.2 0.1 0.13 12.2 0.0 2.1 1 1 1 2 2 2 0 AAA ATPase domain Apo-CIII PF05778.7 ETO32457.1 - 0.017 14.4 0.0 0.038 13.3 0.0 1.6 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) SNARE PF05739.14 ETO32457.1 - 0.13 11.9 0.6 2.6 7.8 0.0 2.9 3 0 0 3 3 3 0 SNARE domain WD40 PF00400.27 ETO32458.1 - 1.2e-53 177.1 4.0 2.7e-12 46.0 0.0 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 ETO32458.1 - 5.8e-08 32.6 0.2 0.00052 19.7 0.1 2.8 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 ETO32458.1 - 6.4e-08 31.7 1.2 0.062 12.0 0.0 3.5 1 1 2 3 3 3 3 Nup133 N terminal like Nup160 PF11715.3 ETO32458.1 - 3.2e-05 22.2 3.2 0.2 9.7 0.0 3.5 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO32458.1 - 4.6e-05 21.8 0.1 0.0056 15.0 0.0 2.0 1 1 2 3 3 3 3 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO32458.1 - 9.2e-05 22.0 0.4 0.0013 18.2 0.2 2.4 1 1 1 2 2 2 2 PQQ-like domain PD40 PF07676.7 ETO32458.1 - 0.00011 21.7 5.4 3.1 7.5 0.0 4.7 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Gmad1 PF10647.4 ETO32458.1 - 0.088 12.1 0.0 0.36 10.1 0.0 2.0 1 1 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain Proteasome_A_N PF10584.4 ETO32458.1 - 0.15 11.3 3.9 30 4.0 0.2 4.3 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Pentaxin PF00354.12 ETO32459.1 - 0.051 12.9 0.2 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 Pentaxin family mRNA_cap_enzyme PF01331.14 ETO32460.1 - 2.5e-05 24.0 1.2 4.6e-05 23.1 0.0 1.9 2 1 0 2 2 2 1 mRNA capping enzyme, catalytic domain Secretin_N_2 PF07655.8 ETO32460.1 - 0.0033 17.7 3.5 0.004 17.5 2.4 1.3 1 0 0 1 1 1 1 Secretin N-terminal domain Radial_spoke PF04712.7 ETO32460.1 - 0.031 13.0 1.4 0.036 12.8 1.0 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Methyltransf_12 PF08242.7 ETO32460.1 - 0.22 12.0 6.2 0.33 11.4 4.3 1.5 1 1 0 1 1 1 0 Methyltransferase domain Eapp_C PF10238.4 ETO32460.1 - 0.3 11.0 11.2 0.45 10.3 7.7 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein Rep_fac-A_C PF08646.5 ETO32461.1 - 1e-29 103.0 0.3 1.3e-29 102.7 0.2 1.1 1 0 0 1 1 1 1 Replication factor-A C terminal domain Arm PF00514.18 ETO32462.1 - 0.0046 16.7 0.0 0.23 11.3 0.0 2.3 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat Hydrolase_3 PF08282.7 ETO32462.1 - 1.2 8.6 5.7 0.63 9.5 1.7 1.8 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase DUF4163 PF13739.1 ETO32462.1 - 1.4 9.7 5.0 0.66 10.7 1.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4163) WD40 PF00400.27 ETO32463.1 - 1.2e-59 196.2 25.8 4.7e-12 45.2 0.1 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO32463.1 - 3.3e-11 42.0 4.0 0.01 14.0 0.1 5.6 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO32463.1 - 5.9e-05 22.0 13.1 4.2 6.0 1.9 5.3 2 1 2 4 4 4 4 Nup133 N terminal like Kelch_4 PF13418.1 ETO32464.1 - 4.3e-06 26.3 1.1 0.00032 20.3 0.1 3.5 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO32464.1 - 5.2e-06 26.3 7.5 0.0017 18.4 0.3 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 ETO32464.1 - 0.15 12.0 4.5 0.35 10.8 0.6 3.2 4 0 0 4 4 4 0 Kelch motif Kelch_3 PF13415.1 ETO32464.1 - 0.19 11.9 0.7 1.7 8.8 0.0 2.8 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO32464.1 - 1 8.9 8.4 1.5 8.4 0.5 3.6 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.10 ETO32464.1 - 2.1 8.2 9.6 13 5.7 0.2 4.0 5 1 0 5 5 5 0 Kelch motif Glyco_hydro_12 PF01670.11 ETO32465.1 - 3e-17 62.8 0.6 5.9e-17 61.8 0.4 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Kelch_1 PF01344.20 ETO32465.1 - 8.5e-06 25.2 0.9 7.4e-05 22.2 0.4 2.4 2 0 0 2 2 2 1 Kelch motif DSPc PF00782.15 ETO32465.1 - 3e-05 23.6 4.5 0.00029 20.4 0.0 3.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Kelch_4 PF13418.1 ETO32465.1 - 4.1e-05 23.2 0.4 0.013 15.2 0.1 2.8 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO32465.1 - 0.00031 20.7 0.4 0.0026 17.8 0.1 2.6 1 1 1 2 2 2 1 Kelch motif Y_phosphatase3 PF13350.1 ETO32465.1 - 0.0038 17.4 0.1 0.0038 17.4 0.1 2.2 2 1 0 2 2 2 1 Tyrosine phosphatase family Kelch_2 PF07646.10 ETO32465.1 - 0.004 16.8 0.3 0.48 10.2 0.3 2.7 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.1 ETO32465.1 - 0.022 14.7 0.5 0.1 12.5 0.3 2.2 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.1 ETO32465.1 - 0.024 14.7 0.0 0.11 12.7 0.0 2.2 1 0 0 1 1 1 0 Galactose oxidase, central domain PTPlike_phytase PF14566.1 ETO32465.1 - 0.056 13.4 1.4 0.15 12.0 0.0 2.3 2 0 0 2 2 2 0 Inositol hexakisphosphate Viral_Beta_CD PF04530.7 ETO32465.1 - 0.1 12.7 3.3 0.097 12.8 0.3 2.4 2 0 0 2 2 2 0 Viral Beta C/D like family UbiD PF01977.11 ETO32465.1 - 0.24 9.8 0.1 0.36 9.2 0.1 1.2 1 0 0 1 1 1 0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase EF-hand_8 PF13833.1 ETO32466.1 - 5.9e-08 32.2 0.2 0.0054 16.3 0.0 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.1 ETO32466.1 - 1.4e-07 31.5 0.2 2.1e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO32466.1 - 2.1e-06 26.6 0.0 0.0093 15.2 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 ETO32466.1 - 0.00099 18.8 0.4 1.3 9.1 0.0 2.6 3 0 0 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.4 ETO32466.1 - 0.0062 16.5 0.2 0.015 15.2 0.1 1.6 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region DUF2135 PF09906.4 ETO32466.1 - 0.0089 15.9 0.6 3.3 7.7 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2135) EF-hand_5 PF13202.1 ETO32466.1 - 0.031 13.6 0.2 7 6.1 0.0 2.5 2 0 0 2 2 2 0 EF hand DUF3006 PF11213.3 ETO32466.1 - 0.044 13.5 0.3 0.077 12.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) DUF1420 PF07220.6 ETO32466.1 - 0.099 10.9 0.5 0.11 10.7 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1420) Protocadherin PF08374.6 ETO32467.1 - 3.2e-05 23.6 1.4 0.057 13.0 0.1 2.4 2 0 0 2 2 2 2 Protocadherin G-alpha PF00503.15 ETO32468.1 - 3.4e-18 65.4 0.6 2.4e-11 42.9 0.1 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AfsA PF03756.8 ETO32468.1 - 0.0044 16.7 0.0 0.006 16.3 0.0 1.1 1 0 0 1 1 1 1 A-factor biosynthesis hotdog domain WD40 PF00400.27 ETO32469.1 - 7.8e-18 63.6 9.5 2.3e-09 36.7 0.5 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 ETO32469.1 - 0.05 13.1 0.0 0.99 8.9 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain TRAM_LAG1_CLN8 PF03798.11 ETO32471.1 - 5.2e-07 29.4 14.4 5.2e-07 29.4 10.0 1.6 2 0 0 2 2 2 1 TLC domain DUF2536 PF10750.4 ETO32472.1 - 0.031 13.8 1.1 0.059 12.9 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2536) Hs1pro-1_N PF07231.7 ETO32472.1 - 0.12 11.9 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 Hs1pro-1 N-terminus EpoR_lig-bind PF09067.5 ETO32472.1 - 1.4 8.9 8.1 0.22 11.5 2.4 2.1 2 1 0 2 2 2 0 Erythropoietin receptor, ligand binding zf-RING_2 PF13639.1 ETO32473.1 - 3e-09 36.5 4.2 4.4e-09 36.0 2.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 ETO32473.1 - 0.00038 20.5 3.6 0.00082 19.4 2.5 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 ETO32473.1 - 0.0013 18.6 2.1 0.0029 17.5 1.5 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_2 PF13923.1 ETO32473.1 - 0.0016 18.4 3.9 0.0025 17.8 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF3449 PF11931.3 ETO32473.1 - 0.0029 17.1 1.3 0.004 16.7 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) zf-C3HC4 PF00097.20 ETO32473.1 - 0.003 17.1 2.4 0.006 16.2 1.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RP-C_C PF11800.3 ETO32473.1 - 0.011 15.4 0.7 0.013 15.2 0.5 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region RINGv PF12906.2 ETO32473.1 - 0.02 14.9 3.7 0.04 13.9 2.5 1.6 1 0 0 1 1 1 0 RING-variant domain zf-Apc11 PF12861.2 ETO32473.1 - 0.025 14.3 1.2 0.043 13.6 0.9 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 ETO32473.1 - 0.04 13.8 1.0 0.084 12.7 0.7 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 ETO32473.1 - 0.1 12.3 2.4 0.2 11.3 1.6 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Menin PF05053.8 ETO32473.1 - 0.92 7.5 5.0 1.1 7.3 3.5 1.1 1 0 0 1 1 1 0 Menin DUF2407_C PF13373.1 ETO32473.1 - 1.4 8.8 5.9 2 8.3 4.1 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain Apis_Csd PF11671.3 ETO32473.1 - 2.4 7.9 17.6 3.9 7.2 12.2 1.4 1 0 0 1 1 1 0 Complementary sex determiner protein DUF3240 PF11582.3 ETO32474.1 - 0.034 14.0 0.1 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3240) Tubulin_C PF03953.12 ETO32475.1 - 6.7e-24 84.3 0.1 2e-23 82.8 0.0 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin PF00091.20 ETO32475.1 - 7.8e-10 38.9 0.0 1.2e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Kelch_6 PF13964.1 ETO32476.1 - 4.6e-08 32.8 1.3 0.098 12.8 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO32476.1 - 1.9e-06 27.3 2.2 0.00063 19.2 0.0 3.9 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO32476.1 - 2.4e-05 24.0 0.1 0.074 12.8 0.0 3.0 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO32476.1 - 0.0014 18.7 0.0 1.1 9.4 0.0 3.3 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO32476.1 - 0.0099 15.6 0.4 1.1 9.1 0.0 3.9 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 ETO32476.1 - 0.016 15.1 0.1 0.42 10.6 0.0 3.1 3 0 0 3 3 3 0 Kelch motif MPP6 PF10175.4 ETO32477.1 - 0.00059 20.1 10.1 0.00059 20.1 7.0 2.4 1 1 1 2 2 2 1 M-phase phosphoprotein 6 Utp14 PF04615.8 ETO32477.1 - 0.087 10.9 31.4 0.1 10.7 21.8 1.0 1 0 0 1 1 1 0 Utp14 protein KdpC PF02669.10 ETO32477.1 - 0.11 12.2 0.4 0.14 11.8 0.3 1.3 1 0 0 1 1 1 0 K+-transporting ATPase, c chain UPF0227 PF05728.7 ETO32477.1 - 0.65 9.7 3.6 0.29 10.8 0.4 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0227) CAP_C PF08603.6 ETO32478.1 - 5.6e-11 42.0 0.5 8.6e-11 41.4 0.3 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 ETO32478.1 - 0.15 11.5 2.8 1.2 8.5 0.4 2.4 1 1 0 2 2 2 0 Tubulin binding cofactor C HSP70 PF00012.15 ETO32479.1 - 0.0019 16.2 0.0 0.0023 15.9 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein WD40 PF00400.27 ETO32480.1 - 9.6e-64 209.1 32.0 1.8e-10 40.3 0.3 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO32480.1 - 1.4e-08 33.3 8.1 0.0084 14.2 0.0 5.0 1 1 4 5 5 5 3 Nucleoporin Nup120/160 DUF1900 PF08954.6 ETO32480.1 - 0.029 13.9 0.1 1.1 8.8 0.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF1900) Herpes_UL6 PF01763.11 ETO32480.1 - 0.062 11.4 3.4 0.088 10.9 2.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like CCDC14 PF15254.1 ETO32480.1 - 3 6.1 12.5 0.12 10.7 4.0 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 14 Peptidase_M18 PF02127.10 ETO32481.1 - 2.9e-14 52.4 0.0 3.1e-14 52.3 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Tubulin_C PF03953.12 ETO32482.1 - 1.1e-46 158.0 0.2 1.8e-46 157.2 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 ETO32482.1 - 5.2e-20 72.1 0.6 2.5e-19 69.9 0.4 2.1 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain 2-Hacid_dh PF00389.25 ETO32482.1 - 0.065 12.7 0.0 0.16 11.4 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Tubulin_2 PF13809.1 ETO32482.1 - 0.071 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Tubulin like EXOSC1 PF10447.4 ETO32483.1 - 2.8e-18 65.6 0.1 8.1e-18 64.1 0.1 1.8 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 ETO32483.1 - 0.014 14.6 0.4 0.044 13.0 0.1 2.0 2 1 0 2 2 2 0 Exosome complex exonuclease RRP4 N-terminal region Prenylcys_lyase PF07156.9 ETO32483.1 - 0.047 12.5 1.2 0.099 11.5 0.0 1.8 1 1 1 2 2 2 0 Prenylcysteine lyase RL11D PF11088.3 ETO32483.1 - 0.099 12.4 2.0 0.24 11.2 1.4 1.7 1 1 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 PH PF00169.24 ETO32484.1 - 8.5e-12 45.2 11.3 3.3e-07 30.4 0.4 3.9 4 1 0 4 4 4 3 PH domain PH_11 PF15413.1 ETO32484.1 - 2.8e-07 30.7 8.2 7.1e-07 29.4 0.1 3.5 4 0 0 4 4 4 2 Pleckstrin homology domain PH_8 PF15409.1 ETO32484.1 - 0.0089 16.0 10.6 0.023 14.7 0.0 3.7 4 0 0 4 4 4 2 Pleckstrin homology domain Acp26Ab PF05777.7 ETO32485.1 - 0.025 15.0 0.0 0.049 14.0 0.0 1.4 1 0 0 1 1 1 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) AAA_13 PF13166.1 ETO32486.1 - 0.0038 15.7 25.3 0.005 15.3 17.5 1.2 1 0 0 1 1 1 1 AAA domain DUF2968 PF11180.3 ETO32486.1 - 0.0063 15.9 14.7 0.0069 15.7 4.3 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2968) Nuc_N PF14448.1 ETO32486.1 - 0.078 12.5 1.6 2 7.9 0.1 3.2 3 1 0 3 3 3 0 Nuclease N terminal DUF2894 PF11445.3 ETO32486.1 - 0.13 12.5 8.0 0.13 12.5 5.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2894) Pox_F16 PF04708.7 ETO32486.1 - 0.17 11.1 7.9 0.85 8.8 0.1 2.5 1 1 0 2 2 2 0 Poxvirus F16 protein IncA PF04156.9 ETO32486.1 - 0.27 10.8 24.0 0.17 11.4 8.2 2.2 1 1 1 2 2 2 0 IncA protein KNOX2 PF03791.8 ETO32486.1 - 0.28 10.5 3.3 1.8 7.8 0.2 3.0 3 0 0 3 3 3 0 KNOX2 domain Spc7 PF08317.6 ETO32486.1 - 0.43 9.1 31.2 0.042 12.4 17.2 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Fmp27_WPPW PF10359.4 ETO32486.1 - 2.1 6.6 24.8 0.13 10.6 10.7 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF4407 PF14362.1 ETO32486.1 - 2.1 7.2 14.1 0.27 10.1 6.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Tweety PF04906.8 ETO32486.1 - 2.5 6.3 6.2 1.5 7.1 3.1 1.5 1 1 0 1 1 1 0 Tweety DUF2400 PF09674.5 ETO32486.1 - 3.7 7.1 12.6 1.1 8.8 6.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) ZYG-11_interact PF05884.7 ETO32486.1 - 4.2 6.3 6.9 2.5 7.1 0.5 2.0 1 1 1 2 2 2 0 Interactor of ZYG-11 DUF904 PF06005.7 ETO32486.1 - 5.2 7.4 37.4 0.13 12.5 3.5 4.3 1 1 3 4 4 4 0 Protein of unknown function (DUF904) Prefoldin_2 PF01920.15 ETO32486.1 - 5.3 6.8 37.4 0.093 12.5 5.0 4.1 3 1 1 4 4 4 0 Prefoldin subunit CorA PF01544.13 ETO32486.1 - 7.8 5.4 13.9 1.5 7.8 5.7 1.9 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein tRNA-synt_His PF13393.1 ETO32486.1 - 7.9 5.4 10.7 1.2 8.1 1.9 2.0 1 1 1 2 2 2 0 Histidyl-tRNA synthetase DUF4293 PF14126.1 ETO32487.1 - 0.0069 16.3 0.5 0.0082 16.0 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4293) ImpA-rel_N PF06812.7 ETO32487.1 - 0.11 12.2 0.5 6.6 6.5 0.0 2.2 2 0 0 2 2 2 0 ImpA-related N-terminal WD40 PF00400.27 ETO32490.1 - 6.5e-18 63.8 2.7 6.3e-07 29.0 1.1 4.6 3 1 0 3 3 3 2 WD domain, G-beta repeat Pentapeptide_3 PF13576.1 ETO32490.1 - 0.027 14.3 0.2 0.052 13.4 0.1 1.5 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETO32490.1 - 0.028 13.6 0.2 0.18 11.0 0.2 2.0 1 1 0 1 1 1 0 Pentapeptide repeats (8 copies) Nucleoporin_N PF08801.6 ETO32490.1 - 0.38 9.4 5.7 0.6 8.7 2.7 2.2 2 1 0 2 2 2 0 Nup133 N terminal like RasGAP_C PF03836.10 ETO32491.1 - 0.013 15.1 1.1 0.013 15.1 0.8 1.9 2 0 0 2 2 2 0 RasGAP C-terminus Na_Ca_ex PF01699.19 ETO32492.1 - 3.4e-19 68.8 16.7 3.4e-19 68.8 11.6 3.0 3 0 0 3 3 3 1 Sodium/calcium exchanger protein Wzy_C PF04932.10 ETO32492.1 - 0.017 14.8 3.3 34 4.1 0.0 3.2 2 2 0 2 2 2 0 O-Antigen ligase CENP-B_dimeris PF09026.5 ETO32492.1 - 0.035 14.3 0.4 0.064 13.5 0.3 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4131 PF13567.1 ETO32492.1 - 4.8 6.5 15.8 11 5.3 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Ribosom_S12_S23 PF00164.20 ETO32493.1 - 4.9e-20 71.1 1.8 7.3e-20 70.6 1.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S12/S23 RPAP2_Rtr1 PF04181.8 ETO32493.1 - 0.041 13.9 0.4 0.15 12.1 0.1 2.0 2 0 0 2 2 2 0 Rtr1/RPAP2 family RolB_RolC PF02027.12 ETO32493.1 - 0.057 12.5 0.0 0.088 11.9 0.0 1.3 1 0 0 1 1 1 0 RolB/RolC glucosidase family WD40 PF00400.27 ETO32495.1 - 8.2e-29 98.4 1.4 5.6e-14 51.3 0.2 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO32495.1 - 0.0014 16.8 0.8 0.036 12.2 0.1 2.4 2 1 1 3 3 3 1 Nucleoporin Nup120/160 PD40 PF07676.7 ETO32495.1 - 0.0029 17.2 0.1 0.86 9.3 0.0 2.4 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat DUF2414 PF10309.4 ETO32495.1 - 0.031 13.9 1.2 0.072 12.7 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2414) Nucleoporin_N PF08801.6 ETO32495.1 - 0.041 12.6 0.5 0.76 8.4 0.4 2.0 1 1 0 1 1 1 0 Nup133 N terminal like Kelch_4 PF13418.1 ETO32495.1 - 0.12 12.1 0.7 1.5 8.6 0.0 2.6 3 0 0 3 3 3 0 Galactose oxidase, central domain WD40 PF00400.27 ETO32496.1 - 1.8e-25 87.8 4.0 6.9e-09 35.2 0.0 3.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO32496.1 - 0.00017 19.8 0.0 0.21 9.6 0.0 2.9 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO32496.1 - 0.00082 18.2 0.6 0.24 10.1 0.0 2.5 2 1 0 2 2 2 2 Nup133 N terminal like Kelch_6 PF13964.1 ETO32496.1 - 0.054 13.6 3.8 3.2 8.0 0.1 3.2 3 0 0 3 3 3 0 Kelch motif WD40 PF00400.27 ETO32497.1 - 1.6e-12 46.8 0.4 3.2e-11 42.6 0.1 2.4 2 1 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO32497.1 - 0.014 13.5 0.0 0.016 13.3 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 MFS_1 PF07690.11 ETO32498.1 - 1.9e-06 26.8 19.4 2.2e-05 23.3 12.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3671 PF12420.3 ETO32498.1 - 0.15 12.0 1.1 1.2 9.1 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF3534 PF12053.3 ETO32499.1 - 2.9 7.7 9.5 1.5 8.6 0.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3534) Nipped-B_C PF12830.2 ETO32500.1 - 5.5e-13 48.9 7.2 2.1e-12 47.0 1.0 3.8 3 1 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 ETO32500.1 - 1.7e-09 37.3 3.1 2.6e-07 30.4 0.3 3.9 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion PHD PF00628.24 ETO32500.1 - 0.0002 20.9 11.6 0.00068 19.2 8.0 2.0 1 0 0 1 1 1 1 PHD-finger HEAT_2 PF13646.1 ETO32500.1 - 0.006 16.8 0.0 1.7 8.9 0.0 3.9 4 1 1 5 5 5 2 HEAT repeats DNA_pack_N PF02500.10 ETO32501.1 - 0.041 13.4 0.5 0.044 13.3 0.3 1.3 1 0 0 1 1 1 0 Probable DNA packing protein, N-terminus FolB PF02152.13 ETO32501.1 - 0.067 13.3 0.2 0.099 12.8 0.1 1.3 1 0 0 1 1 1 0 Dihydroneopterin aldolase Fcf2 PF08698.6 ETO32501.1 - 0.65 10.0 7.7 0.097 12.6 1.8 2.2 2 1 0 2 2 2 0 Fcf2 pre-rRNA processing DUF4519 PF15012.1 ETO32501.1 - 9.5 6.2 10.2 6.2 6.8 1.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4519) Anoctamin PF04547.7 ETO32502.1 - 1.4e-33 116.2 2.6 1.6e-33 116.0 1.8 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel LMBR1 PF04791.11 ETO32502.1 - 0.00011 21.0 0.7 0.00011 21.0 0.5 1.6 2 0 0 2 2 2 1 LMBR1-like membrane protein Pox_E10 PF04805.7 ETO32502.1 - 0.1 12.1 1.9 1.1 8.7 0.1 2.7 2 0 0 2 2 2 0 E10-like protein conserved region DUF4200 PF13863.1 ETO32502.1 - 2 8.3 14.0 2.8 7.9 9.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Protocadherin PF08374.6 ETO32502.1 - 3.4 7.2 6.1 4.6 6.8 4.2 1.2 1 0 0 1 1 1 0 Protocadherin SecA_DEAD PF07517.9 ETO32503.1 - 8.4e-06 25.2 0.3 5e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 SecA DEAD-like domain Anoctamin PF04547.7 ETO32504.1 - 1.8e-48 165.3 22.5 2.7e-45 154.8 15.6 2.1 1 1 0 1 1 1 1 Calcium-activated chloride channel DUF2975 PF11188.3 ETO32504.1 - 0.039 13.6 0.2 0.039 13.6 0.1 2.9 3 2 1 4 4 4 0 Protein of unknown function (DUF2975) PH PF00169.24 ETO32505.1 - 2.6e-10 40.4 0.3 2.6e-10 40.4 0.2 2.1 1 1 1 2 2 2 1 PH domain PH_8 PF15409.1 ETO32505.1 - 0.0053 16.8 3.1 0.04 13.9 2.2 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain Mcp5_PH PF12814.2 ETO32505.1 - 0.0072 16.2 2.6 0.015 15.2 1.8 1.6 1 1 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH_3 PF14593.1 ETO32505.1 - 0.0073 16.1 4.2 0.1 12.4 2.5 2.3 1 1 0 1 1 1 1 PH domain MAS20 PF02064.10 ETO32505.1 - 0.047 13.6 0.8 0.072 13.0 0.6 1.4 1 0 0 1 1 1 0 MAS20 protein import receptor PH_11 PF15413.1 ETO32505.1 - 0.11 12.7 8.4 0.21 11.8 1.7 2.8 2 1 0 2 2 2 0 Pleckstrin homology domain Aspzincin_M35 PF14521.1 ETO32506.1 - 0.0015 19.0 1.2 0.0021 18.6 0.8 1.3 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Sec16_N PF12935.2 ETO32506.1 - 0.0061 16.4 6.1 0.009 15.9 4.2 1.2 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 N-terminus PhnJ PF06007.6 ETO32507.1 - 0.088 11.5 0.0 0.22 10.2 0.0 1.6 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ DUF3160 PF11369.3 ETO32508.1 - 0.012 13.9 0.3 0.1 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3160) Cwf_Cwc_15 PF04889.7 ETO32508.1 - 0.014 15.1 4.4 0.025 14.2 3.1 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NHase_beta PF02211.10 ETO32508.1 - 0.032 13.9 0.0 0.049 13.3 0.0 1.2 1 0 0 1 1 1 0 Nitrile hydratase beta subunit MFS_1 PF07690.11 ETO32509.1 - 1.3e-11 43.8 2.8 3.8e-11 42.3 2.2 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETO32509.1 - 7.5e-07 28.0 2.7 7.5e-07 28.0 1.8 1.6 1 1 1 2 2 2 1 Sugar (and other) transporter Nucleoside_tran PF01733.13 ETO32509.1 - 0.00049 19.3 0.6 0.063 12.4 0.0 2.1 1 1 1 2 2 2 2 Nucleoside transporter Herpes_BTRF1 PF04682.7 ETO32509.1 - 0.055 12.7 0.2 0.082 12.2 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus BTRF1 protein conserved region ABC_tran PF00005.22 ETO32510.1 - 2.1e-11 44.2 0.0 2.5e-11 44.0 0.0 1.0 1 0 0 1 1 1 1 ABC transporter FH2 PF02181.18 ETO32514.1 - 1.1e-29 103.5 14.2 2e-28 99.3 9.9 2.9 1 1 0 1 1 1 1 Formin Homology 2 Domain DDE_Tnp_IS1595 PF12762.2 ETO32514.1 - 0.027 14.3 1.2 0.12 12.1 0.2 2.4 2 0 0 2 2 2 0 ISXO2-like transposase domain PPR PF01535.15 ETO32516.1 - 0.0066 16.3 0.2 6.2 7.0 0.1 3.9 4 0 0 4 4 4 1 PPR repeat PPR_2 PF13041.1 ETO32516.1 - 0.02 14.8 0.3 1.7 8.6 0.0 3.3 3 0 0 3 3 3 0 PPR repeat family PPR_2 PF13041.1 ETO32517.1 - 8e-10 38.5 2.0 9.4e-07 28.7 0.0 3.8 3 1 2 5 5 5 3 PPR repeat family PPR_3 PF13812.1 ETO32517.1 - 0.0014 18.7 0.2 0.028 14.7 0.0 3.1 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR PF01535.15 ETO32517.1 - 0.0025 17.6 0.1 0.027 14.4 0.0 2.6 2 0 0 2 2 2 1 PPR repeat HTH_36 PF13730.1 ETO32517.1 - 0.0056 16.7 0.0 0.021 14.9 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain PPR_1 PF12854.2 ETO32517.1 - 0.035 13.5 0.0 1.6 8.2 0.0 3.0 3 0 0 3 3 3 0 PPR repeat APC_CDC26 PF10471.4 ETO32517.1 - 0.22 12.3 1.1 0.41 11.4 0.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 WD40 PF00400.27 ETO32518.1 - 3.9e-10 39.1 2.3 0.23 11.3 0.2 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO32518.1 - 2.2e-06 26.2 0.3 0.014 13.6 0.1 2.4 2 0 0 2 2 2 2 Cytochrome D1 heme domain Hira PF07569.6 ETO32518.1 - 0.0081 15.4 0.1 0.42 9.7 0.0 3.4 1 1 1 3 3 3 1 TUP1-like enhancer of split PD40 PF07676.7 ETO32518.1 - 0.011 15.3 1.8 1.1 8.9 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF1963 PF09234.5 ETO32518.1 - 0.5 10.5 8.5 0.99 9.5 5.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1963) BAF PF02961.9 ETO32519.1 - 0.1 12.9 0.2 0.21 11.9 0.2 1.5 1 0 0 1 1 1 0 Barrier to autointegration factor TRAP-gamma PF07074.7 ETO32520.1 - 0.054 13.0 1.0 0.066 12.7 0.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) FmdE PF02663.9 ETO32520.1 - 0.29 11.0 2.0 0.41 10.5 1.4 1.1 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon WD40 PF00400.27 ETO32521.1 - 1.6e-60 198.9 6.3 7.6e-13 47.8 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO32521.1 - 6.3e-09 34.5 1.9 0.053 11.6 0.0 4.9 2 1 3 5 5 5 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO32521.1 - 2.3e-05 23.9 0.2 0.00043 19.8 0.1 2.4 2 1 0 2 2 2 1 PQQ-like domain PD40 PF07676.7 ETO32521.1 - 0.00012 21.6 2.0 2.5 7.8 0.0 4.9 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO32521.1 - 0.0014 17.4 4.5 2.1 6.9 0.0 3.8 2 1 2 4 4 4 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO32521.1 - 0.0035 15.6 0.0 2.8 6.1 0.0 3.4 2 1 2 4 4 4 1 Cytochrome D1 heme domain Mid2 PF04478.7 ETO32521.1 - 0.0036 16.7 4.5 2.6 7.4 0.1 4.8 1 1 5 6 6 6 1 Mid2 like cell wall stress sensor Me-amine-dh_H PF06433.6 ETO32521.1 - 0.0067 15.1 0.0 2 6.9 0.0 3.4 4 0 0 4 4 4 1 Methylamine dehydrogenase heavy chain (MADH) Nbas_N PF15492.1 ETO32521.1 - 0.011 14.8 0.6 4.5 6.3 0.1 3.7 3 2 2 5 5 5 0 Neuroblastoma-amplified sequence, N terminal DPPIV_N PF00930.16 ETO32521.1 - 0.1 11.1 0.1 9.6 4.6 0.0 3.1 1 1 3 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Ricin_B_lectin PF00652.17 ETO32521.1 - 0.18 11.8 5.7 0.54 10.2 1.0 3.1 1 1 2 3 3 3 0 Ricin-type beta-trefoil lectin domain Proteasome_A_N PF10584.4 ETO32521.1 - 2.4 7.5 8.5 9.2 5.7 0.0 4.2 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Ras PF00071.17 ETO32522.1 - 2.5e-59 199.2 0.1 4e-59 198.6 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO32522.1 - 2.6e-19 69.8 0.0 5.6e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO32522.1 - 3.3e-13 49.2 0.0 4.6e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETO32522.1 - 1.3e-05 24.4 0.0 1.7e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 ETO32522.1 - 2e-05 24.0 0.1 0.00028 20.3 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 ETO32522.1 - 4.3e-05 23.4 0.0 0.00018 21.4 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETO32522.1 - 0.05 12.8 0.1 0.46 9.7 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.22 ETO32522.1 - 0.1 12.8 0.2 0.15 12.3 0.1 1.7 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 ETO32522.1 - 0.11 12.6 0.0 0.29 11.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain Fibrinogen_BP PF08017.6 ETO32523.1 - 0.037 12.2 0.5 0.054 11.7 0.3 1.3 1 0 0 1 1 1 0 Fibrinogen binding protein CK2S PF15011.1 ETO32524.1 - 0.042 13.6 2.6 0.19 11.4 0.1 2.6 1 1 1 3 3 3 0 Casein Kinase 2 substrate AAA_13 PF13166.1 ETO32524.1 - 0.043 12.2 6.5 0.048 12.1 4.5 1.0 1 0 0 1 1 1 0 AAA domain zf-C4H2 PF10146.4 ETO32524.1 - 0.058 13.4 7.1 0.082 12.9 4.9 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein UreF PF01730.11 ETO32524.1 - 0.068 13.2 0.2 0.16 12.1 0.1 1.6 1 1 1 2 2 2 0 UreF ALIX_LYPXL_bnd PF13949.1 ETO32524.1 - 0.079 11.9 0.3 0.079 11.9 0.2 2.1 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV DNA_Packaging PF11053.3 ETO32524.1 - 0.11 12.0 2.4 0.15 11.6 1.2 1.6 1 1 0 1 1 1 0 Terminase DNA packaging enzyme DUF2664 PF10867.3 ETO32524.1 - 0.14 12.7 2.0 2.1 9.0 0.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2664) MCPsignal PF00015.16 ETO32524.1 - 0.23 10.9 4.0 3.8 6.9 0.3 2.0 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain G-gamma PF00631.17 ETO32524.1 - 0.62 9.8 3.8 11 5.8 0.1 3.2 2 1 1 3 3 3 0 GGL domain DUF2570 PF10828.3 ETO32524.1 - 0.72 9.4 5.1 0.67 9.5 1.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2570) WEMBL PF05701.6 ETO32526.1 - 7.3e-05 21.4 49.3 7.3e-05 21.4 34.2 7.4 3 2 3 7 7 7 2 Weak chloroplast movement under blue light Lge1 PF11488.3 ETO32526.1 - 0.0056 16.8 0.1 0.0056 16.8 0.1 15.9 7 4 6 13 13 13 1 Transcriptional regulatory protein LGE1 Reo_sigmaC PF04582.7 ETO32526.1 - 5.5 6.0 73.8 0.11 11.7 3.7 9.1 6 3 5 11 11 11 0 Reovirus sigma C capsid protein WD40 PF00400.27 ETO32527.1 - 2.7e-14 52.4 12.4 0.0035 17.1 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat Spore_coat_CotO PF14153.1 ETO32527.1 - 0.003 17.0 11.3 0.003 17.0 7.8 3.1 3 0 0 3 3 3 1 Spore coat protein CotO Nop14 PF04147.7 ETO32527.1 - 4.7 5.0 35.8 0.37 8.6 21.2 1.6 2 0 0 2 2 2 0 Nop14-like family NACHT PF05729.7 ETO32528.1 - 6.1e-19 68.2 0.0 3.1e-18 66.0 0.0 2.0 1 1 0 1 1 1 1 NACHT domain DUF87 PF01935.12 ETO32528.1 - 0.00093 19.0 1.2 0.034 13.9 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_22 PF13401.1 ETO32528.1 - 0.0044 17.1 0.1 0.014 15.5 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 ETO32528.1 - 0.015 15.6 0.0 0.015 15.6 0.0 2.5 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.17 ETO32528.1 - 0.021 13.7 0.0 0.089 11.6 0.0 2.1 1 1 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.1 ETO32528.1 - 0.042 13.8 0.0 0.31 10.9 0.0 2.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 ETO32528.1 - 0.093 12.1 0.1 0.5 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain AAA_17 PF13207.1 ETO32528.1 - 1.4 9.7 5.6 0.45 11.3 0.1 2.8 2 2 0 2 2 2 0 AAA domain Upf2 PF04050.9 ETO32529.1 - 0.0029 17.4 19.6 0.0029 17.4 13.6 2.9 3 0 0 3 3 3 1 Up-frameshift suppressor 2 RR_TM4-6 PF06459.7 ETO32529.1 - 0.0052 16.7 16.3 0.0052 16.7 11.3 2.2 2 0 0 2 2 2 1 Ryanodine Receptor TM 4-6 DUF3527 PF12043.3 ETO32529.1 - 2.6 7.5 13.8 0.084 12.3 4.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3527) DUF3246 PF11596.3 ETO32529.1 - 5.3 6.2 18.1 0.04 13.1 5.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3246) TMP PF05017.9 ETO32533.1 - 0.5 10.9 2.3 55 4.9 0.0 3.9 3 0 0 3 3 3 0 TMP repeat DUF3785 PF12653.2 ETO32535.1 - 0.051 13.4 0.3 0.096 12.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3785) MRF_C2 PF13888.1 ETO32535.1 - 0.099 12.4 0.2 0.25 11.1 0.0 1.7 2 0 0 2 2 2 0 Myelin gene regulatory factor C-terminal domain 2 F-box-like PF12937.2 ETO32537.1 - 8e-05 22.2 0.4 0.00013 21.5 0.3 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETO32537.1 - 0.00017 21.1 0.2 0.00017 21.1 0.1 1.5 2 0 0 2 2 2 1 F-box domain PYST-C1 PF09690.5 ETO32537.1 - 0.24 11.0 2.7 0.51 10.0 1.9 1.5 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) TPR_12 PF13424.1 ETO32538.1 - 2.2e-64 213.3 23.8 1.2e-21 76.4 0.6 3.3 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO32538.1 - 1.8e-30 103.9 0.0 6.6e-08 32.2 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO32538.1 - 6.8e-29 98.2 26.7 4.3e-09 35.5 1.3 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO32538.1 - 6.2e-28 94.3 6.9 1.8e-06 27.3 0.0 5.2 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETO32538.1 - 3.7e-27 92.0 21.8 4.6e-08 32.3 1.1 5.3 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETO32538.1 - 4.7e-25 87.0 16.6 7.2e-09 35.1 3.4 3.4 3 1 0 3 3 3 3 TPR repeat TPR_8 PF13181.1 ETO32538.1 - 5.5e-17 60.1 29.8 4.9e-06 25.9 1.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO32538.1 - 1.5e-11 44.5 0.2 1.8e-05 25.2 0.1 4.1 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO32538.1 - 2.1e-10 40.3 11.4 0.023 15.1 0.1 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO32538.1 - 1.2e-09 37.5 6.7 0.038 14.1 0.1 5.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO32538.1 - 4.6e-08 33.0 0.0 0.32 11.7 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO32538.1 - 8.6e-08 31.3 0.6 0.061 12.5 0.0 4.3 4 0 0 4 4 4 2 SHNi-TPR TPR_3 PF07720.7 ETO32538.1 - 2.6e-07 30.3 15.2 0.00012 21.7 1.5 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO32538.1 - 2.3e-05 24.6 0.6 0.33 11.3 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO32538.1 - 2.7e-05 24.2 16.3 0.002 18.2 1.0 4.2 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF2225 PF09986.4 ETO32538.1 - 0.0001 21.8 14.0 0.00094 18.6 2.0 2.4 1 1 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.13 ETO32538.1 - 0.00068 19.4 11.2 0.049 13.5 0.1 4.9 5 0 0 5 5 5 1 MIT (microtubule interacting and transport) domain PPR PF01535.15 ETO32538.1 - 0.0021 17.8 2.0 32 4.8 0.0 5.0 5 0 0 5 5 5 0 PPR repeat DUF627 PF04781.7 ETO32538.1 - 0.039 13.5 7.3 5.5 6.6 0.7 4.0 2 2 1 3 3 3 0 Protein of unknown function (DUF627) DUF2164 PF09932.4 ETO32538.1 - 0.05 13.4 3.7 1.5 8.7 0.1 3.3 4 0 0 4 4 3 0 Uncharacterized conserved protein (DUF2164) Sel1 PF08238.7 ETO32538.1 - 0.11 13.1 14.7 3 8.6 0.2 5.2 5 0 0 5 5 5 0 Sel1 repeat Glyoxalase PF00903.20 ETO32538.1 - 0.21 11.5 1.2 2.3 8.1 0.0 2.5 2 1 1 3 3 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Fis1_TPR_C PF14853.1 ETO32538.1 - 0.54 10.1 17.0 0.45 10.4 0.8 4.0 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Inhibitor_I29 PF08246.7 ETO32538.1 - 1.9 8.8 11.6 0.6 10.4 1.1 3.7 3 1 1 4 4 4 0 Cathepsin propeptide inhibitor domain (I29) Mito_fiss_reg PF05308.6 ETO32539.1 - 5.8 6.2 10.7 9.3 5.5 7.4 1.4 1 1 0 1 1 1 0 Mitochondrial fission regulator RXT2_N PF08595.6 ETO32540.1 - 0.013 15.2 1.5 0.022 14.5 1.0 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Trypan_PARP PF05887.6 ETO32540.1 - 0.24 11.1 8.7 0.34 10.7 6.0 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF2254 PF10011.4 ETO32540.1 - 0.28 9.6 1.2 0.38 9.1 0.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) DUF4238 PF14022.1 ETO32540.1 - 0.4 9.9 7.4 0.58 9.3 4.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4238) CobT PF06213.7 ETO32540.1 - 1.5 7.8 9.5 2.2 7.3 6.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT KilA-N PF04383.8 ETO32540.1 - 1.8 8.2 5.2 3.1 7.4 2.6 2.1 2 1 0 2 2 2 0 KilA-N domain Daxx PF03344.10 ETO32540.1 - 6 5.2 12.5 7.7 4.8 8.6 1.1 1 0 0 1 1 1 0 Daxx Family Herpes_gE PF02480.11 ETO32541.1 - 0.0062 14.8 0.0 0.007 14.6 0.0 1.0 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E VSP PF03302.8 ETO32541.1 - 0.02 13.5 0.3 0.026 13.1 0.2 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein GAPT PF11770.3 ETO32541.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) WD40 PF00400.27 ETO32542.1 - 6.6e-159 510.8 48.6 5.7e-14 51.3 0.0 15.8 16 0 0 16 16 16 15 WD domain, G-beta repeat DPPIV_N PF00930.16 ETO32542.1 - 2.4e-08 32.9 0.8 0.19 10.2 0.0 6.8 2 1 7 9 9 9 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Pentapeptide PF00805.17 ETO32542.1 - 4.7e-05 22.5 0.6 0.00011 21.2 0.4 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO32542.1 - 0.00012 21.7 0.4 0.00038 20.1 0.3 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) DUF1652 PF07865.6 ETO32542.1 - 0.00014 21.3 0.2 10 5.8 0.0 6.1 8 0 0 8 8 8 2 Protein of unknown function (DUF1652) Str_synth PF03088.11 ETO32542.1 - 0.00022 21.1 0.3 1.3 9.0 0.0 5.5 6 1 1 7 7 7 1 Strictosidine synthase Pentapeptide_3 PF13576.1 ETO32542.1 - 0.00074 19.3 0.3 0.0022 17.8 0.2 1.9 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) PD40 PF07676.7 ETO32542.1 - 0.0069 16.0 15.0 28 4.5 0.1 7.7 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat F420_ligase PF01996.11 ETO32542.1 - 0.017 14.2 0.1 2.1 7.3 0.0 3.5 2 1 1 4 4 4 0 F420-0:Gamma-glutamyl ligase DUF2681 PF10883.3 ETO32546.1 - 0.027 14.6 0.3 0.031 14.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) SPC22 PF04573.7 ETO32546.1 - 0.16 11.2 1.0 0.18 10.9 0.7 1.0 1 0 0 1 1 1 0 Signal peptidase subunit DUF3552 PF12072.3 ETO32546.1 - 0.19 10.8 3.2 0.23 10.6 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) WD40 PF00400.27 ETO32547.1 - 3.4e-41 137.6 8.9 9.1e-12 44.3 0.0 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO32547.1 - 6.3e-08 31.2 0.5 4.5e-05 21.7 0.2 2.7 1 1 2 3 3 3 2 Nucleoporin Nup120/160 DUF605 PF04652.11 ETO32548.1 - 0.54 9.6 23.3 0.6 9.4 16.2 1.1 1 0 0 1 1 1 0 Vta1 like SprA-related PF12118.3 ETO32548.1 - 2.7 7.2 23.3 3.5 6.8 16.1 1.1 1 0 0 1 1 1 0 SprA-related family TPR_11 PF13414.1 ETO32549.1 - 9.3e-09 34.8 4.4 2e-05 24.1 0.3 3.0 1 1 2 3 3 3 3 TPR repeat TPR_17 PF13431.1 ETO32549.1 - 7.3e-08 32.0 1.6 0.096 12.9 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO32549.1 - 0.00032 20.1 10.2 0.78 9.4 0.3 5.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO32549.1 - 0.00055 19.8 2.2 0.25 11.2 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO32549.1 - 0.0009 19.6 0.7 0.18 12.5 0.2 2.9 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO32549.1 - 0.0015 18.3 7.7 1.6 8.8 0.3 4.8 3 2 0 3 3 3 2 Tetratricopeptide repeat Alpha-2-MRAP_N PF06400.6 ETO32549.1 - 0.026 14.2 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, N-terminal domain FAT PF02259.18 ETO32549.1 - 0.03 13.2 0.1 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 FAT domain TPR_19 PF14559.1 ETO32549.1 - 0.045 14.0 0.1 13 6.2 0.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat adh_short PF00106.20 ETO32550.1 - 1.7e-19 70.3 0.0 2e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETO32550.1 - 2.4e-09 37.2 0.0 3e-09 37.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETO32550.1 - 0.00014 21.5 0.0 0.00025 20.7 0.0 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 ETO32550.1 - 0.13 11.6 0.0 0.32 10.4 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 2OG-FeII_Oxy PF03171.15 ETO32551.1 - 0.00019 21.6 0.6 0.0018 18.5 0.0 2.5 2 2 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Choline_kinase PF01633.15 ETO32552.1 - 0.00028 20.5 0.0 0.0005 19.6 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF4498 PF14926.1 ETO32552.1 - 0.074 12.1 0.8 0.11 11.5 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4498) Choline_kinase PF01633.15 ETO32553.1 - 1.2e-26 93.6 6.8 1.2e-26 93.6 4.7 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 ETO32553.1 - 7.5e-06 25.8 0.4 1.1e-05 25.3 0.3 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family TPR_14 PF13428.1 ETO32555.1 - 2.3e-06 27.7 1.0 0.49 11.1 0.0 4.7 1 1 4 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO32555.1 - 3.1e-06 26.7 16.0 0.057 13.0 0.0 4.1 2 1 2 4 4 4 3 TPR repeat TPR_1 PF00515.23 ETO32555.1 - 0.0028 17.2 9.2 0.53 9.9 0.2 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO32555.1 - 0.0042 16.8 16.8 1.5 8.9 0.1 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO32555.1 - 0.0069 17.0 3.8 2 9.2 0.2 3.2 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO32555.1 - 0.0081 16.0 14.0 0.081 12.8 0.3 4.3 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO32555.1 - 0.0088 15.7 13.3 0.058 13.2 0.2 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO32555.1 - 0.0089 16.3 5.7 2.2 8.6 0.0 3.6 4 1 0 4 4 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO32555.1 - 0.02 14.6 4.6 3.8 7.5 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Astro_capsid PF03115.9 ETO32555.1 - 0.049 11.8 7.6 0.081 11.1 5.3 1.3 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Spore_coat_CotO PF14153.1 ETO32555.1 - 0.087 12.2 20.2 0.18 11.2 8.7 2.3 2 0 0 2 2 2 0 Spore coat protein CotO Paf1 PF03985.8 ETO32555.1 - 0.12 11.0 24.6 0.32 9.6 17.0 1.7 1 0 0 1 1 1 0 Paf1 DDHD PF02862.12 ETO32555.1 - 0.13 12.0 5.7 0.36 10.6 0.8 2.4 2 0 0 2 2 2 0 DDHD domain Nop14 PF04147.7 ETO32555.1 - 0.28 9.0 34.3 0.55 8.0 23.8 1.4 1 0 0 1 1 1 0 Nop14-like family Apc3 PF12895.2 ETO32555.1 - 1.8 8.7 12.0 30 4.8 7.0 3.0 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Daxx PF03344.10 ETO32555.1 - 2.4 6.5 39.9 2.6 6.4 23.7 2.2 2 0 0 2 2 2 0 Daxx Family NOA36 PF06524.7 ETO32555.1 - 2.5 7.2 22.6 5.3 6.2 15.7 1.5 1 0 0 1 1 1 0 NOA36 protein Zip PF02535.17 ETO32555.1 - 4 6.3 7.5 4 6.3 2.4 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter CDC45 PF02724.9 ETO32555.1 - 6.4 4.6 30.5 0.075 11.0 15.8 1.7 2 0 0 2 2 2 0 CDC45-like protein TPR_17 PF13431.1 ETO32555.1 - 8.4 6.8 6.2 28 5.2 0.9 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat cNMP_binding PF00027.24 ETO32557.1 - 6.3e-31 106.0 0.9 4.4e-15 55.2 0.1 3.6 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain Nucleoplasmin PF03066.10 ETO32557.1 - 0.013 15.0 7.6 2.2 7.7 3.5 2.4 2 0 0 2 2 2 0 Nucleoplasmin RNB PF00773.14 ETO32558.1 - 2.1e-20 73.2 0.6 2.7e-20 72.8 0.4 1.2 1 0 0 1 1 1 1 RNB domain ECIST_Cterm PF14784.1 ETO32559.1 - 0.039 13.8 1.0 0.066 13.1 0.2 1.7 1 1 1 2 2 2 0 C-terminal domain of the ECSIT protein Hydrolase_like2 PF13246.1 ETO32559.1 - 1.5 8.8 4.3 2.5 8.1 0.2 2.5 2 1 0 2 2 2 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Vasculin PF15337.1 ETO32560.1 - 0.012 16.0 0.2 0.015 15.7 0.2 1.2 1 0 0 1 1 1 0 Vascular protein family Vasculin-like 1 Imm3 PF14425.1 ETO32560.1 - 0.16 11.8 0.7 1.6 8.7 0.1 2.0 1 1 1 2 2 2 0 Immunity protein Imm3 RasGEF_N PF00618.15 ETO32560.1 - 0.25 11.4 2.3 2.4 8.3 1.2 2.4 1 1 1 2 2 2 0 RasGEF N-terminal motif ASCH PF04266.9 ETO32561.1 - 8.1e-06 26.1 0.4 7.6e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 ASCH domain MAP65_ASE1 PF03999.7 ETO32561.1 - 0.026 13.1 2.0 0.46 9.0 0.3 2.1 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) DUF3782 PF12644.2 ETO32561.1 - 0.11 12.2 0.2 5.4 6.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3782) NYD-SP28 PF14772.1 ETO32561.1 - 0.82 9.7 4.1 12 6.0 0.9 2.4 2 0 0 2 2 2 0 Sperm tail EMP24_GP25L PF01105.19 ETO32562.1 - 0.16 11.6 1.5 0.23 11.1 1.0 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD NPCC PF08058.6 ETO32562.1 - 7.1 6.4 8.0 4.5 7.1 1.6 2.1 1 1 1 2 2 2 0 Nuclear pore complex component DRMBL PF07522.9 ETO32563.1 - 2e-16 60.0 3.9 2.9e-16 59.4 0.2 3.0 2 2 1 3 3 3 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 ETO32563.1 - 8.8e-05 22.1 1.8 0.00031 20.3 0.0 2.6 3 1 1 4 4 4 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 ETO32563.1 - 0.019 14.6 0.0 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily CENP-B_dimeris PF09026.5 ETO32563.1 - 0.19 12.0 17.1 0.51 10.6 11.9 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SR-25 PF10500.4 ETO32563.1 - 6 6.2 24.8 0.13 11.7 7.2 2.5 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein Eapp_C PF10238.4 ETO32566.1 - 0.013 15.3 5.8 0.013 15.3 4.0 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein Methyltransf_12 PF08242.7 ETO32566.1 - 1.6 9.2 6.5 0.63 10.5 1.5 2.3 2 0 0 2 2 2 0 Methyltransferase domain MT-A70 PF05063.9 ETO32567.1 - 3.3e-07 30.0 3.3 9.4e-06 25.3 2.3 2.2 1 1 0 1 1 1 1 MT-A70 ATP1G1_PLM_MAT8 PF02038.11 ETO32567.1 - 0.12 11.3 0.6 0.3 10.1 0.4 1.7 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family DUF1132 PF06575.7 ETO32570.1 - 1.3 9.3 7.0 0.31 11.3 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1132) TLD PF07534.11 ETO32571.1 - 4.2e-07 30.0 0.2 5.7e-05 23.1 0.1 2.5 2 0 0 2 2 2 2 TLD Acyl_CoA_thio PF02551.10 ETO32572.1 - 0.0086 15.7 2.0 0.012 15.2 1.4 1.4 1 1 0 1 1 1 1 Acyl-CoA thioesterase EcsB PF05975.7 ETO32572.1 - 0.2 10.0 4.8 0.2 10.0 3.3 1.1 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB Bac_transf PF02397.11 ETO32572.1 - 1.2 8.2 4.1 1.6 7.8 1.0 1.9 1 1 1 2 2 2 0 Bacterial sugar transferase RNase_H2-Ydr279 PF09468.5 ETO32573.1 - 4.1e-36 124.7 6.0 6.5e-36 124.0 4.1 1.4 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Cut8_N PF14482.1 ETO32573.1 - 0.012 15.5 3.4 0.037 14.0 2.3 1.8 1 0 0 1 1 1 0 Cut8 proteasome-binding domain CAMSAP_CKK PF08683.6 ETO32573.1 - 0.058 13.1 0.4 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 Microtubule-binding calmodulin-regulated spectrin-associated DUF211 PF02680.9 ETO32575.1 - 2.5 7.9 7.8 4.2 7.2 0.2 2.7 2 1 0 2 2 2 0 Uncharacterized ArCR, COG1888 FtsJ PF01728.14 ETO32576.1 - 1.2e-12 48.2 0.3 1.6e-12 47.7 0.2 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Cullin_binding PF03556.10 ETO32576.1 - 0.017 15.2 2.0 0.026 14.6 1.0 1.9 1 1 1 2 2 2 0 Cullin binding tRNA_anti-codon PF01336.20 ETO32577.1 - 1.1e-07 31.6 0.0 2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF307 PF03733.8 ETO32577.1 - 0.00052 20.3 11.2 0.00092 19.5 7.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF307) DUF1227 PF06777.6 ETO32578.1 - 0.76 9.4 7.6 0.058 13.0 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1227) T4SS PF07996.6 ETO32579.1 - 0.087 12.6 9.6 0.016 15.0 1.1 3.0 2 1 0 2 2 2 0 Type IV secretion system proteins CS PF04969.11 ETO32580.1 - 2.2e-17 63.3 2.8 3.9e-17 62.5 1.9 1.4 1 0 0 1 1 1 1 CS domain XPA_C PF05181.7 ETO32580.1 - 0.086 12.4 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 XPA protein C-terminus Sod_Fe_C PF02777.13 ETO32580.1 - 0.098 12.4 1.7 1.3 8.8 0.1 2.3 2 0 0 2 2 2 0 Iron/manganese superoxide dismutases, C-terminal domain zf-RanBP PF00641.13 ETO32581.1 - 0.0003 19.8 2.1 0.0003 19.8 1.5 2.2 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others DUF2616 PF11077.3 ETO32581.1 - 0.014 14.8 2.3 0.03 13.8 1.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2616) DZR PF12773.2 ETO32581.1 - 0.054 13.3 2.7 0.2 11.4 1.9 1.8 1 1 1 2 2 2 0 Double zinc ribbon DUF2082 PF09855.4 ETO32581.1 - 0.12 12.2 1.0 6.1 6.7 0.1 2.3 2 0 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Vpu PF00558.14 ETO32581.1 - 0.64 9.6 2.6 1.2 8.7 1.8 1.4 1 0 0 1 1 1 0 Vpu protein C1_3 PF07649.7 ETO32581.1 - 5.4 7.1 6.2 90 3.2 0.1 3.1 3 0 0 3 3 3 0 C1-like domain Pkinase PF00069.20 ETO32582.1 - 0.0001 21.5 0.0 0.00015 21.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 ETO32583.1 - 2.1e-14 52.7 0.8 3e-08 33.2 0.0 2.6 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO32583.1 - 0.00073 17.7 0.2 0.18 9.8 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Kelch_1 PF01344.20 ETO32584.1 - 3.2e-09 36.1 1.0 1.3e-07 31.0 0.4 2.6 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.1 ETO32584.1 - 2.4e-07 30.3 0.3 0.00041 20.0 0.0 2.5 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO32584.1 - 2.7e-07 30.4 1.8 3.9e-05 23.6 0.1 2.7 2 1 1 3 3 3 2 Kelch motif Kelch_3 PF13415.1 ETO32584.1 - 0.00021 21.3 0.0 0.00074 19.6 0.0 1.9 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO32584.1 - 0.00038 20.3 2.6 0.0012 18.7 0.4 2.6 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO32584.1 - 0.00061 19.4 0.3 0.075 12.8 0.2 2.7 2 0 0 2 2 2 1 Kelch motif WD40 PF00400.27 ETO32585.1 - 2.7e-37 125.2 0.6 1.7e-11 43.5 0.1 4.7 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 ETO32585.1 - 3.1e-06 27.0 1.0 0.00041 20.1 0.0 2.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO32585.1 - 4.7e-05 22.9 2.9 0.034 13.8 0.0 4.0 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.9 ETO32585.1 - 0.0002 20.3 1.8 0.00026 19.9 1.3 1.3 1 0 0 1 1 1 1 Coatomer WD associated region Cytochrom_D1 PF02239.11 ETO32585.1 - 0.00034 19.0 0.3 0.007 14.7 0.0 2.2 1 1 1 2 2 2 2 Cytochrome D1 heme domain SGL PF08450.7 ETO32585.1 - 0.0019 17.6 0.1 0.0046 16.3 0.1 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region B_lectin PF01453.19 ETO32585.1 - 0.0032 17.3 1.2 0.24 11.3 0.0 2.7 1 1 2 3 3 3 1 D-mannose binding lectin Imm14 PF15428.1 ETO32585.1 - 0.028 14.8 0.4 0.24 11.8 0.1 2.2 1 1 1 2 2 2 0 Immunity protein 14 DUF2711 PF10924.3 ETO32585.1 - 0.054 12.9 0.0 0.089 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2711) Proteasome_A_N PF10584.4 ETO32585.1 - 0.5 9.7 4.1 24 4.3 0.0 3.6 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Fez1 PF06818.10 ETO32586.1 - 0.0044 17.0 10.2 0.0051 16.8 7.1 1.1 1 0 0 1 1 1 1 Fez1 DUF2584 PF10763.4 ETO32586.1 - 0.034 13.9 3.3 0.055 13.2 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2584) Flagellin_C PF00700.16 ETO32586.1 - 0.041 14.0 1.0 0.063 13.4 0.6 1.5 1 1 0 1 1 1 0 Bacterial flagellin C-terminal helical region RLL PF10036.4 ETO32586.1 - 0.045 13.1 6.1 0.052 12.9 4.2 1.0 1 0 0 1 1 1 0 Putative carnitine deficiency-associated protein Spc7 PF08317.6 ETO32586.1 - 0.051 12.2 13.3 0.059 12.0 9.2 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Glutaredoxin2_C PF04399.8 ETO32586.1 - 0.13 11.8 4.2 0.18 11.4 2.9 1.1 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain DUF641 PF04859.7 ETO32586.1 - 0.18 11.5 7.8 0.23 11.1 5.4 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF1818 PF08848.6 ETO32586.1 - 0.19 11.7 3.0 0.22 11.5 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1818) Exonuc_VII_L PF02601.10 ETO32586.1 - 0.49 9.5 7.6 0.58 9.2 5.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit HlyD PF00529.15 ETO32586.1 - 0.69 9.1 5.6 0.78 8.9 3.9 1.0 1 0 0 1 1 1 0 HlyD family secretion protein ERM PF00769.14 ETO32586.1 - 0.84 9.1 18.2 1 8.8 12.6 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family CENP-Q PF13094.1 ETO32586.1 - 1.3 8.9 16.2 1.6 8.7 11.2 1.0 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3552 PF12072.3 ETO32586.1 - 1.4 8.0 18.3 2.2 7.4 12.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Macoilin PF09726.4 ETO32586.1 - 1.5 7.0 13.2 1.5 6.9 9.2 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF4407 PF14362.1 ETO32586.1 - 2.1 7.2 6.6 2.4 7.0 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PEARLI-4 PF05278.7 ETO32586.1 - 2.5 7.3 15.7 3.7 6.8 10.9 1.4 1 1 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF4047 PF13256.1 ETO32586.1 - 2.7 7.9 9.5 3.1 7.7 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) IncA PF04156.9 ETO32586.1 - 2.7 7.5 11.0 3.4 7.2 7.6 1.1 1 0 0 1 1 1 0 IncA protein Borrelia_P83 PF05262.6 ETO32586.1 - 3.1 5.9 14.5 3.7 5.6 10.1 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein GCD14 PF08704.5 ETO32586.1 - 4.5 6.6 5.4 5.4 6.4 3.7 1.0 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit V_ATPase_I PF01496.14 ETO32586.1 - 5.6 4.6 7.1 6.1 4.5 4.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SlyX PF04102.7 ETO32586.1 - 7.5 7.0 7.3 10 6.5 5.1 1.3 1 0 0 1 1 1 0 SlyX NAM-associated PF14303.1 ETO32586.1 - 7.6 6.8 14.1 9.6 6.5 9.8 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF3373 PF11853.3 ETO32586.1 - 8.5 4.7 6.0 9.4 4.6 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) ABC_tran PF00005.22 ETO32587.1 - 3.8e-08 33.7 0.0 4.6e-08 33.4 0.0 1.0 1 0 0 1 1 1 1 ABC transporter RQC PF09382.5 ETO32587.1 - 0.12 12.1 0.1 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 RQC domain GnsAB PF08178.6 ETO32588.1 - 0.043 13.4 1.7 0.082 12.5 1.1 1.4 1 0 0 1 1 1 0 GnsA/GnsB family WD40 PF00400.27 ETO32589.1 - 1.2e-23 82.0 15.0 7.4e-12 44.6 0.5 4.6 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO32589.1 - 0.00029 19.1 2.6 0.028 12.5 0.0 2.7 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Spore_YhcN_YlaJ PF09580.5 ETO32590.1 - 0.032 14.3 0.2 0.053 13.6 0.1 1.4 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) MvaI_BcnI PF15515.1 ETO32590.1 - 0.12 12.4 4.9 0.14 12.1 3.4 1.0 1 0 0 1 1 1 0 MvaI/BcnI restriction endonuclease family Secretin_N_2 PF07655.8 ETO32590.1 - 7.4 7.0 11.0 13 6.2 7.6 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain DUF3196 PF11428.3 ETO32591.1 - 0.075 12.3 0.1 0.094 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3196) RRM_1 PF00076.17 ETO32592.1 - 1.3e-17 63.1 0.1 8.9e-16 57.2 0.0 3.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO32592.1 - 3e-14 52.7 0.0 5.4e-13 48.7 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO32592.1 - 5e-06 26.2 0.0 1.2e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DIL PF01843.14 ETO32593.1 - 5e-08 32.7 0.3 1.4e-07 31.3 0.2 1.8 1 0 0 1 1 1 1 DIL domain RUN PF02759.14 ETO32593.1 - 0.027 14.2 1.0 0.19 11.5 1.0 2.2 2 0 0 2 2 2 0 RUN domain WD40 PF00400.27 ETO32594.1 - 3.5e-66 216.8 20.0 2.9e-12 45.9 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO32594.1 - 7.5e-07 27.6 1.5 0.13 10.3 0.0 3.3 2 1 1 3 3 3 3 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO32594.1 - 5.5e-06 26.2 1.0 0.6 10.0 0.0 5.3 3 2 3 6 6 6 1 Domain of unknown function (DUF3601) Cytochrom_D1 PF02239.11 ETO32594.1 - 3.5e-05 22.2 0.3 0.035 12.3 0.0 2.5 2 1 0 2 2 2 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO32594.1 - 6.1e-05 22.5 0.1 0.00034 20.1 0.0 2.3 1 1 0 1 1 1 1 PQQ-like domain DPPIV_N PF00930.16 ETO32594.1 - 0.0001 21.0 0.0 0.039 12.5 0.0 3.6 2 2 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.7 ETO32594.1 - 0.0019 17.8 5.8 32 4.3 0.0 6.0 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO32594.1 - 0.0026 17.9 2.4 2.7 8.3 0.0 4.1 2 1 2 4 4 4 1 Resistin Proteasome_A_N PF10584.4 ETO32594.1 - 1.3 8.3 7.5 27 4.2 0.1 4.3 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature WWE PF02825.15 ETO32597.1 - 2.9e-13 49.0 2.3 2.6e-07 29.9 0.5 2.4 2 0 0 2 2 2 2 WWE domain zf-RING_2 PF13639.1 ETO32597.1 - 1.9e-08 34.0 9.5 3.6e-08 33.1 6.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 ETO32597.1 - 4.6e-06 26.2 14.1 2.2e-05 24.0 9.8 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO32597.1 - 1.3e-05 25.1 13.3 8.4e-05 22.5 9.3 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO32597.1 - 1.8e-05 24.3 12.5 9.3e-05 22.0 8.6 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 ETO32597.1 - 0.00017 21.4 15.4 0.00033 20.4 6.7 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 ETO32597.1 - 0.0015 18.2 12.0 0.0076 15.9 8.1 2.3 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 ETO32597.1 - 0.0043 16.7 7.2 0.015 14.9 5.0 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.15 ETO32597.1 - 1.3 8.5 11.9 8.9 5.9 3.3 3.2 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger Prok-RING_4 PF14447.1 ETO32597.1 - 1.4 8.5 7.4 1.1 8.8 1.7 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-XS PF03470.9 ETO32597.1 - 3.2 7.8 7.6 8.9 6.4 0.9 2.8 2 0 0 2 2 2 0 XS zinc finger domain zf-C3HC4_3 PF13920.1 ETO32598.1 - 2.1e-07 30.5 8.8 3.9e-07 29.6 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO32598.1 - 0.00064 19.6 10.5 0.0013 18.6 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO32598.1 - 0.0029 17.2 9.4 0.0074 15.9 6.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO32598.1 - 0.029 14.0 12.3 0.056 13.1 8.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain BUD22 PF09073.5 ETO32598.1 - 0.059 12.4 31.6 0.091 11.8 21.9 1.3 1 0 0 1 1 1 0 BUD22 TFIIF_alpha PF05793.7 ETO32598.1 - 0.12 10.7 41.3 0.15 10.3 28.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Prok-RING_4 PF14447.1 ETO32598.1 - 0.18 11.3 6.4 0.39 10.3 4.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.1 ETO32598.1 - 0.24 11.2 8.0 0.51 10.2 5.5 1.6 1 0 0 1 1 1 0 Ring finger domain Daxx PF03344.10 ETO32598.1 - 2 6.7 44.1 3.8 5.8 30.6 1.4 1 1 0 1 1 1 0 Daxx Family CDC45 PF02724.9 ETO32599.1 - 0.0045 15.1 1.3 0.0045 15.1 0.9 1.9 2 0 0 2 2 2 1 CDC45-like protein Mem_trans PF03547.13 ETO32599.1 - 0.28 9.4 5.1 0.019 13.3 0.2 1.5 2 0 0 2 2 2 0 Membrane transport protein ATP-grasp_4 PF13535.1 ETO32600.1 - 2.9e-20 72.7 0.0 1.6e-19 70.3 0.0 2.2 3 0 0 3 3 3 1 ATP-grasp domain CPSase_L_D2 PF02786.12 ETO32600.1 - 9.4e-09 34.8 0.0 4.8e-08 32.5 0.0 1.9 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.1 ETO32600.1 - 3.9e-08 32.4 0.0 6.8e-06 25.0 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 ETO32600.1 - 0.00011 22.0 0.0 0.00049 20.0 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain Nop14 PF04147.7 ETO32600.1 - 0.00025 19.1 23.1 0.00025 19.1 16.0 1.8 2 0 0 2 2 2 1 Nop14-like family GARS_A PF01071.14 ETO32600.1 - 0.001 18.6 0.0 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Dala_Dala_lig_C PF07478.8 ETO32600.1 - 0.033 13.5 0.0 0.068 12.5 0.0 1.5 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus TFIIA PF03153.8 ETO32600.1 - 0.56 10.0 26.1 1.2 8.9 18.1 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Astro_capsid PF03115.9 ETO32600.1 - 0.68 8.1 4.4 0.94 7.6 3.1 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor CENP-T PF15511.1 ETO32600.1 - 0.92 8.6 13.1 1.4 8.0 9.1 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CDC45 PF02724.9 ETO32600.1 - 2 6.3 21.2 3.4 5.6 14.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 ETO32600.1 - 5.3 5.3 26.0 0.4 9.1 14.6 1.5 2 0 0 2 2 2 0 Daxx Family VWA_2 PF13519.1 ETO32601.1 - 2e-07 31.2 0.0 4.3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 ETO32601.1 - 1.2e-05 25.0 0.1 2.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.15 ETO32601.1 - 0.12 12.0 10.5 0.15 11.6 2.3 2.8 2 0 0 2 2 2 0 Ubiquitin interaction motif Pox_Ag35 PF03286.9 ETO32602.1 - 0.12 11.9 9.7 0.14 11.6 6.7 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4662 PF15578.1 ETO32602.1 - 0.39 10.2 8.0 0.44 10.0 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) FAM75 PF14650.1 ETO32602.1 - 1 8.6 6.9 1.1 8.5 4.8 1.0 1 0 0 1 1 1 0 FAM75 family DUF2947 PF11163.3 ETO32603.1 - 0.01 15.3 0.1 0.017 14.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) Ribosomal_L14 PF00238.14 ETO32603.1 - 0.051 13.3 0.5 2.3 7.9 0.1 2.1 2 0 0 2 2 2 0 Ribosomal protein L14p/L23e WD40 PF00400.27 ETO32604.1 - 1.9e-48 160.6 17.4 3.4e-10 39.3 0.1 8.0 7 1 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO32604.1 - 0.0088 15.7 0.5 1.1 8.9 0.2 3.0 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO32604.1 - 0.056 11.5 0.2 0.26 9.3 0.2 1.9 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Rav1p_C PF12234.3 ETO32605.1 - 1.3e-42 145.8 5.1 3.2e-42 144.5 3.6 1.5 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 ETO32605.1 - 0.036 13.9 10.4 11 6.0 0.0 6.2 6 0 0 6 6 6 0 WD domain, G-beta repeat HSP20 PF00011.16 ETO32606.1 - 0.074 12.9 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Hsp20/alpha crystallin family Sec5 PF15469.1 ETO32607.1 - 1.8e-25 89.7 8.5 3.3e-25 88.8 5.9 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.6 ETO32607.1 - 2e-16 59.5 2.4 2e-16 59.5 1.7 2.9 3 1 1 4 4 4 1 Vps51/Vps67 Dor1 PF04124.7 ETO32607.1 - 2e-10 39.6 12.6 3.1e-10 39.0 8.7 1.2 1 0 0 1 1 1 1 Dor1-like family DUF2450 PF10475.4 ETO32607.1 - 1.7e-07 30.4 7.8 3.1e-07 29.6 5.4 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) COG5 PF10392.4 ETO32607.1 - 4.5e-05 23.4 0.5 4.5e-05 23.4 0.3 2.7 2 1 0 2 2 2 1 Golgi transport complex subunit 5 COG2 PF06148.6 ETO32607.1 - 0.0001 22.1 3.7 0.0001 22.1 2.6 2.1 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps53_N PF04100.7 ETO32607.1 - 0.00026 19.9 7.6 0.0004 19.2 5.3 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal XhlA PF10779.4 ETO32607.1 - 0.079 12.8 1.5 0.34 10.8 1.1 2.1 1 0 0 1 1 1 0 Haemolysin XhlA DUF948 PF06103.6 ETO32607.1 - 0.12 12.2 2.0 0.82 9.5 0.3 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.7 ETO32607.1 - 0.29 10.8 5.5 0.1 12.3 1.0 2.3 2 1 0 2 2 2 0 Laminin Domain II Sipho_Gp157 PF05565.6 ETO32607.1 - 0.96 9.0 11.3 0.13 11.8 2.7 2.4 2 0 0 2 2 2 0 Siphovirus Gp157 Occludin_ELL PF07303.8 ETO32608.1 - 0.55 11.0 10.0 0.38 11.5 1.0 3.6 2 1 1 3 3 3 0 Occludin homology domain Pox_A_type_inc PF04508.7 ETO32608.1 - 0.61 10.0 4.0 1.9 8.4 0.6 3.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Seryl_tRNA_N PF02403.17 ETO32608.1 - 1.1 9.3 20.7 0.057 13.4 6.8 3.0 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Fzo_mitofusin PF04799.8 ETO32608.1 - 2.6 7.4 13.0 0.27 10.6 5.9 1.6 2 0 0 2 2 2 0 fzo-like conserved region Fez1 PF06818.10 ETO32608.1 - 3 7.8 16.7 0.21 11.6 7.4 2.1 2 1 0 2 2 2 0 Fez1 FlaC_arch PF05377.6 ETO32608.1 - 3.2 7.6 8.5 13 5.7 4.6 2.9 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Adeno_PIX PF03955.9 ETO32608.1 - 9.3 6.8 6.9 21 5.6 1.6 2.7 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) A_deaminase PF00962.17 ETO32609.1 - 8.2e-08 31.5 0.0 1.4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase WGG PF10273.4 ETO32609.1 - 0.042 13.9 2.8 0.2 11.7 1.9 2.2 1 1 0 1 1 1 0 Pre-rRNA-processing protein TSR2 RGS PF00615.14 ETO32609.1 - 0.064 13.3 0.1 0.083 12.9 0.1 1.2 1 0 0 1 1 1 0 Regulator of G protein signaling domain Ras PF00071.17 ETO32611.1 - 7.3e-52 175.0 5.3 5e-45 152.7 1.2 2.4 1 1 1 2 2 2 2 Ras family Miro PF08477.8 ETO32611.1 - 9.1e-16 58.4 0.3 4.2e-15 56.2 0.0 2.2 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO32611.1 - 4.9e-10 38.9 1.6 1.4e-08 34.1 0.3 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO32611.1 - 1.8e-07 30.7 0.1 2.3e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF3584 PF12128.3 ETO32613.1 - 0.00016 19.2 3.7 0.00019 18.9 2.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) OmpH PF03938.9 ETO32613.1 - 0.098 12.5 5.9 0.12 12.3 4.1 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) IncA PF04156.9 ETO32613.1 - 2.3 7.7 9.6 3.3 7.2 6.7 1.3 1 1 0 1 1 1 0 IncA protein DUF1342 PF07072.6 ETO32614.1 - 0.00016 21.3 3.9 0.00018 21.2 2.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1342) Mnd1 PF03962.10 ETO32614.1 - 0.0078 15.8 5.2 0.0091 15.6 3.6 1.1 1 0 0 1 1 1 1 Mnd1 family CAS_CSE1 PF03378.10 ETO32614.1 - 0.025 12.8 1.3 0.024 12.9 0.9 1.0 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus Lyase_8_N PF08124.6 ETO32614.1 - 0.034 13.0 3.4 0.035 12.9 2.3 1.0 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain TPR_MLP1_2 PF07926.7 ETO32614.1 - 0.054 13.2 8.9 0.071 12.8 6.2 1.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4319 PF14203.1 ETO32614.1 - 0.067 12.7 0.6 0.15 11.6 0.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4319) CENP-Q PF13094.1 ETO32614.1 - 0.14 12.1 6.2 0.18 11.7 4.3 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Herpes_UL33 PF03581.8 ETO32614.1 - 0.16 11.8 1.6 0.27 11.1 0.1 1.9 2 0 0 2 2 2 0 Herpesvirus UL33-like protein TBPIP PF07106.8 ETO32614.1 - 0.38 10.2 11.5 0.44 10.0 7.9 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Bap31 PF05529.7 ETO32614.1 - 0.74 9.2 7.7 0.44 9.9 4.3 1.4 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like KLRAQ PF10205.4 ETO32614.1 - 0.75 9.8 7.9 0.44 10.5 4.4 1.4 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein CCDC-167 PF15188.1 ETO32614.1 - 0.77 9.7 5.4 0.93 9.4 3.0 1.8 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 YlbD_coat PF14071.1 ETO32614.1 - 1.3 9.1 7.6 0.89 9.6 4.0 1.6 1 1 1 2 2 2 0 Putative coat protein FlaC_arch PF05377.6 ETO32614.1 - 1.4 8.8 6.8 4.1 7.3 1.7 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Atg14 PF10186.4 ETO32614.1 - 6.1 5.7 9.3 6.1 5.6 6.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 WD40 PF00400.27 ETO32615.1 - 5.7e-14 51.3 3.4 8.2e-06 25.5 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Fez1 PF06818.10 ETO32615.1 - 0.2 11.6 28.6 0.38 10.7 19.9 1.5 1 0 0 1 1 1 0 Fez1 ADIP PF11559.3 ETO32615.1 - 0.46 10.3 37.4 0.13 12.1 11.6 3.2 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 ETO32615.1 - 1.8 7.6 6.1 3.9 6.5 3.1 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Spc7 PF08317.6 ETO32615.1 - 4.7 5.7 36.3 0.26 9.8 13.9 2.6 1 1 1 2 2 2 0 Spc7 kinetochore protein AAA_13 PF13166.1 ETO32615.1 - 7.2 4.9 26.0 10 4.4 18.0 1.2 1 0 0 1 1 1 0 AAA domain DUF3573 PF12097.3 ETO32615.1 - 7.2 5.1 7.1 11 4.4 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) WD40 PF00400.27 ETO32617.1 - 1.6e-25 87.9 5.8 2.7e-10 39.7 0.0 4.3 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO32617.1 - 0.005 15.0 0.1 0.25 9.4 0.1 2.3 1 1 2 3 3 3 3 Nucleoporin Nup120/160 HAD PF12710.2 ETO32617.1 - 0.15 12.2 1.3 1.6 8.8 0.1 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Ion_trans PF00520.26 ETO32618.1 - 4.9e-27 94.4 18.0 6.7e-27 94.0 12.5 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.7 ETO32618.1 - 7.7e-06 24.5 10.8 0.007 14.8 2.2 2.1 1 1 1 2 2 2 2 Polycystin cation channel DUF2299 PF10061.4 ETO32619.1 - 0.029 13.8 0.2 0.059 12.8 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2299) PNTB PF02233.11 ETO32620.1 - 4.4e-182 606.0 17.5 4.4e-182 606.0 12.1 2.2 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 ETO32620.1 - 2.6e-55 186.5 0.3 2.6e-55 186.5 0.2 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 ETO32620.1 - 1.7e-43 147.9 0.0 3e-43 147.0 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 ETO32620.1 - 5.5e-32 109.7 2.5 5.5e-32 109.7 1.8 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 ETO32620.1 - 0.0041 16.3 0.3 0.79 8.8 0.0 3.4 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_31 PF13847.1 ETO32620.1 - 0.017 14.6 0.0 0.047 13.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Pyr_redox PF00070.22 ETO32620.1 - 0.093 13.1 0.6 0.29 11.5 0.4 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETO32620.1 - 0.13 12.0 0.9 0.67 9.8 0.3 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.20 ETO32621.1 - 6.5e-38 130.3 1.0 5.3e-28 97.8 0.3 2.2 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO32621.1 - 9.3e-17 60.9 1.5 3e-13 49.4 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 ETO32621.1 - 1.5e-06 27.4 0.2 0.00042 19.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pox_ser-thr_kin PF05445.6 ETO32621.1 - 0.00054 18.8 0.1 0.00087 18.1 0.1 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase PIP5K PF01504.13 ETO32622.1 - 4.5e-20 71.8 0.2 6.2e-20 71.3 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase PIP5K PF01504.13 ETO32623.1 - 1e-25 90.3 0.2 1e-25 90.3 0.1 1.4 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Nop14 PF04147.7 ETO32624.1 - 0.0028 15.6 9.4 0.0032 15.4 6.5 1.1 1 0 0 1 1 1 1 Nop14-like family Lin-8 PF03353.10 ETO32624.1 - 0.017 14.4 7.8 0.022 14.0 5.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Daxx PF03344.10 ETO32624.1 - 0.053 12.0 8.5 0.06 11.8 5.9 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 ETO32624.1 - 0.082 10.9 6.9 0.096 10.7 4.8 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 ETO32624.1 - 0.14 11.3 9.5 0.22 10.7 6.6 1.3 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.6 ETO32624.1 - 0.33 8.7 6.4 0.42 8.4 4.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CobT PF06213.7 ETO32624.1 - 1.1 8.2 12.8 1.4 7.9 8.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT YL1 PF05764.8 ETO32624.1 - 1.2 8.6 11.9 1.9 8.0 8.2 1.3 1 0 0 1 1 1 0 YL1 nuclear protein RXT2_N PF08595.6 ETO32624.1 - 2 8.2 9.7 0.33 10.7 4.0 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal TRAP_alpha PF03896.11 ETO32624.1 - 4 6.3 10.0 6 5.7 6.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RRN3 PF05327.6 ETO32624.1 - 4.4 5.2 7.5 5.3 5.0 5.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2207 PF09972.4 ETO32625.1 - 0.11 11.0 5.9 0.11 11.0 4.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) GP41 PF00517.12 ETO32625.1 - 0.3 10.6 7.9 0.41 10.1 5.5 1.2 1 0 0 1 1 1 0 Retroviral envelope protein Shisa PF13908.1 ETO32625.1 - 3.1 7.9 7.6 4.9 7.3 5.3 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Herpes_LMP1 PF05297.6 ETO32625.1 - 3.1 6.6 8.1 3.6 6.4 5.6 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Baculo_E56 PF04639.7 ETO32625.1 - 8.7 4.8 9.0 13 4.3 6.2 1.2 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope Sdh_cyt PF01127.17 ETO32626.1 - 0.011 15.5 0.1 0.013 15.2 0.1 1.1 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit HemY_N PF07219.8 ETO32626.1 - 0.43 10.1 2.1 0.43 10.1 0.8 1.6 2 0 0 2 2 2 0 HemY protein N-terminus DUF4149 PF13664.1 ETO32626.1 - 0.46 10.5 4.5 0.61 10.1 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) DivIC PF04977.10 ETO32627.1 - 0.00059 19.2 7.8 0.00059 19.2 5.4 2.5 3 0 0 3 3 3 1 Septum formation initiator PgaD PF13994.1 ETO32627.1 - 0.0064 15.9 4.1 0.012 15.1 2.8 1.4 1 0 0 1 1 1 1 PgaD-like protein PspB PF06667.7 ETO32627.1 - 0.026 14.4 1.6 0.026 14.4 1.1 1.8 2 0 0 2 2 2 0 Phage shock protein B IncA PF04156.9 ETO32627.1 - 0.059 12.9 15.5 0.23 11.0 8.3 2.2 2 0 0 2 2 2 0 IncA protein DUF2434 PF10361.4 ETO32627.1 - 0.06 12.4 3.1 0.067 12.2 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) Peroxin-13_N PF04088.8 ETO32627.1 - 0.073 13.0 9.3 1 9.2 1.0 2.7 2 1 1 3 3 3 0 Peroxin 13, N-terminal region OPA3 PF07047.7 ETO32627.1 - 0.082 12.6 5.7 0.028 14.1 1.4 2.0 2 0 0 2 2 2 0 Optic atrophy 3 protein (OPA3) DUF3573 PF12097.3 ETO32627.1 - 0.1 11.2 7.4 0.12 10.9 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) 5_nucleotid PF05761.9 ETO32627.1 - 0.13 10.7 5.2 0.19 10.2 3.6 1.1 1 0 0 1 1 1 0 5' nucleotidase family DUF2681 PF10883.3 ETO32627.1 - 0.23 11.6 22.0 0.19 11.9 7.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) Activator_LAG-3 PF11498.3 ETO32627.1 - 0.37 9.4 34.6 0.4 9.3 24.0 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Hep_59 PF07052.6 ETO32627.1 - 0.6 10.5 6.5 3 8.2 0.8 2.3 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 PSCyt3 PF07627.6 ETO32627.1 - 0.6 9.9 6.7 0.099 12.5 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) PAT1 PF09770.4 ETO32627.1 - 0.91 7.6 28.6 1.1 7.3 19.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2269 PF10027.4 ETO32627.1 - 1.1 8.9 5.2 0.21 11.3 1.1 1.6 2 0 0 2 2 1 0 Predicted integral membrane protein (DUF2269) DUF4094 PF13334.1 ETO32627.1 - 1.6 9.1 9.4 0.25 11.7 1.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DUF106 PF01956.11 ETO32627.1 - 1.7 8.1 8.7 0.26 10.8 2.9 1.8 2 0 0 2 2 2 0 Integral membrane protein DUF106 PulG PF11773.3 ETO32627.1 - 1.8 8.3 16.9 0.17 11.6 6.3 2.2 2 0 0 2 2 2 0 Type II secretory pathway pseudopilin DUF4140 PF13600.1 ETO32627.1 - 2 8.8 12.4 2.2 8.7 4.8 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Cytochrome_C554 PF13435.1 ETO32627.1 - 5.1 7.1 9.5 0.72 9.9 1.4 2.2 2 0 0 2 2 2 0 Cytochrome c554 and c-prime YlqD PF11068.3 ETO32627.1 - 5.2 7.1 23.3 2.3 8.2 10.7 2.2 2 0 0 2 2 2 0 YlqD protein Med15 PF09606.5 ETO32627.1 - 5.8 4.9 36.5 7.2 4.6 25.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ctr PF04145.10 ETO32627.1 - 6.9 6.7 7.0 8.3 6.4 4.3 1.7 1 1 0 1 1 1 0 Ctr copper transporter family TFIIA PF03153.8 ETO32627.1 - 7.7 6.2 20.6 9.7 5.9 14.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ABC2_membrane PF01061.19 ETO32628.1 - 0.13 11.3 7.3 0.24 10.5 5.1 1.3 1 0 0 1 1 1 0 ABC-2 type transporter HXXEE PF13787.1 ETO32628.1 - 0.16 12.3 3.1 0.27 11.6 1.4 2.0 2 1 0 2 2 2 0 Protein of unknown function with HXXEE motif DUF3021 PF11457.3 ETO32628.1 - 1.3 8.9 9.0 4.3 7.2 6.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3021) Pex14_N PF04695.8 ETO32630.1 - 0.088 12.8 0.3 0.13 12.2 0.2 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NRDE-2 PF08424.5 ETO32630.1 - 1.3 7.8 8.0 1.9 7.3 5.6 1.2 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Tetraspannin PF00335.15 ETO32630.1 - 2.3 7.4 12.1 0.97 8.6 0.7 2.2 2 0 0 2 2 2 0 Tetraspanin family CbiQ PF02361.11 ETO32631.1 - 3 7.3 12.4 13 5.2 7.9 2.2 1 1 0 1 1 1 0 Cobalt transport protein Lipase_3 PF01764.20 ETO32632.1 - 1.1e-16 60.7 0.0 2.1e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF4252 PF14060.1 ETO32632.1 - 0.075 12.5 0.2 0.27 10.8 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) EF-hand_1 PF00036.27 ETO32635.1 - 3.6e-14 50.9 0.8 4.3e-06 25.6 0.2 2.9 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 ETO32635.1 - 2.2e-12 46.8 3.7 5.5e-12 45.6 1.4 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO32635.1 - 4.7e-10 38.4 2.5 0.00049 19.7 0.0 3.6 3 1 2 5 5 5 2 EF-hand domain EF-hand_5 PF13202.1 ETO32635.1 - 2.2e-07 29.9 1.0 0.016 14.5 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 ETO32635.1 - 4e-07 29.5 2.4 6.5e-05 22.4 0.1 3.2 3 0 0 3 3 3 1 EF-hand domain pair SPARC_Ca_bdg PF10591.4 ETO32635.1 - 0.00078 19.4 1.4 0.002 18.1 0.4 1.9 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 ETO32635.1 - 0.018 14.7 0.1 0.029 14.0 0.1 1.4 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 ETO32635.1 - 0.074 12.7 1.1 4.5 7.0 0.0 2.5 2 0 0 2 2 2 0 EF hand YqcI_YcgG PF08892.6 ETO32635.1 - 0.095 12.2 0.1 0.21 11.0 0.0 1.5 2 0 0 2 2 2 0 YqcI/YcgG family Pkinase PF00069.20 ETO32636.1 - 7.8e-42 143.2 5.2 7.2e-24 84.3 3.5 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO32636.1 - 1.1e-16 60.6 3.2 1.5e-11 43.8 1.9 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 ETO32636.1 - 1.1e-06 28.5 2.1 1.2e-05 25.2 0.0 2.4 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 ETO32636.1 - 7.1e-05 21.9 0.1 0.00015 20.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 ETO32636.1 - 0.00017 21.0 0.0 0.00044 19.6 0.0 1.7 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 ETO32636.1 - 0.00088 18.9 0.8 0.0016 18.0 0.1 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kinase-like PF14531.1 ETO32636.1 - 0.002 17.1 0.1 0.74 8.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.17 ETO32636.1 - 0.0044 16.3 1.9 0.0046 16.3 0.1 1.9 2 0 0 2 2 2 1 RIO1 family DUF4642 PF15484.1 ETO32637.1 - 0.00016 21.6 2.9 0.00025 21.0 2.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4642) DUF2052 PF09747.4 ETO32637.1 - 0.0012 18.7 3.5 0.0017 18.2 2.4 1.2 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Cas_Csy4 PF09618.5 ETO32637.1 - 0.0028 17.4 0.9 0.0039 17.0 0.6 1.2 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Csy4) FAM176 PF14851.1 ETO32637.1 - 0.0035 17.0 0.9 0.0059 16.2 0.6 1.3 1 0 0 1 1 1 1 FAM176 family DUF3886 PF13025.1 ETO32637.1 - 0.025 14.5 16.6 0.045 13.7 11.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Dzip-like_N PF13815.1 ETO32637.1 - 0.039 13.7 4.6 0.067 13.0 3.2 1.3 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Cytomega_UL84 PF06284.6 ETO32637.1 - 0.1 10.9 0.3 0.12 10.7 0.2 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Pox_Ag35 PF03286.9 ETO32637.1 - 0.2 11.1 5.8 0.3 10.5 4.0 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF3824 PF12868.2 ETO32637.1 - 0.34 11.8 6.6 0.52 11.2 4.6 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Sporozoite_P67 PF05642.6 ETO32637.1 - 0.54 8.0 2.6 0.7 7.6 1.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CMS1 PF14617.1 ETO32637.1 - 1.5 7.8 4.6 2.1 7.3 3.2 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF3682 PF12446.3 ETO32637.1 - 5 7.4 10.4 7.8 6.7 7.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Spore_YhcN_YlaJ PF09580.5 ETO32638.1 - 0.11 12.5 19.0 0.18 11.8 13.1 1.4 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) PH_4 PF15404.1 ETO32638.1 - 2.6 7.5 17.2 0.54 9.7 7.7 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain Zn_ribbon_recom PF13408.1 ETO32639.1 - 0.92 9.8 6.2 3.7 7.8 4.3 2.1 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain DeoRC PF00455.17 ETO32641.1 - 0.018 14.7 0.1 6.4 6.3 0.0 2.3 2 0 0 2 2 2 0 DeoR C terminal sensor domain DUF3301 PF11743.3 ETO32641.1 - 0.07 12.6 0.3 0.41 10.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) DNA_pol_A_exo1 PF01612.15 ETO32642.1 - 6.2e-20 71.3 0.0 1e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease AntA PF08346.7 ETO32643.1 - 0.29 11.3 5.9 6.6 7.0 0.3 2.4 2 0 0 2 2 2 0 AntA/AntB antirepressor CDC45 PF02724.9 ETO32645.1 - 0.056 11.4 4.5 0.05 11.6 3.1 1.0 1 0 0 1 1 1 0 CDC45-like protein PAP_central PF04928.12 ETO32647.1 - 0.0073 15.1 0.1 2.9 6.6 0.0 2.1 1 1 1 2 2 2 2 Poly(A) polymerase central domain Calici_coat_C PF08435.6 ETO32647.1 - 0.064 12.5 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal YojJ PF10372.4 ETO32647.1 - 0.091 12.6 0.4 0.76 9.6 0.0 2.5 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus MS_channel PF00924.13 ETO32647.1 - 0.098 11.9 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel Mem_trans PF03547.13 ETO32648.1 - 0.4 8.9 2.5 0.45 8.7 1.7 1.1 1 0 0 1 1 1 0 Membrane transport protein Kei1 PF08552.6 ETO32648.1 - 5 6.7 6.9 37 3.9 4.8 1.9 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 TP53IP5 PF15331.1 ETO32648.1 - 6.9 6.5 9.1 8.5 6.2 6.3 1.0 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Pkinase PF00069.20 ETO32649.1 - 2.6e-36 125.0 0.0 3.2e-31 108.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO32649.1 - 1.9e-23 82.8 0.0 3.3e-21 75.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 ETO32649.1 - 0.0025 16.8 0.0 0.28 10.1 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 ETO32649.1 - 0.0038 17.0 0.0 0.008 15.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 ETO32649.1 - 0.075 12.0 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4270 PF14092.1 ETO32651.1 - 0.015 13.9 0.6 0.018 13.7 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4270) MOSC_N PF03476.11 ETO32651.1 - 0.015 14.9 1.0 0.023 14.3 0.4 1.4 1 1 1 2 2 2 0 MOSC N-terminal beta barrel domain PAPA-1 PF04795.7 ETO32651.1 - 0.017 15.8 7.4 0.074 13.7 0.0 2.1 2 0 0 2 2 2 0 PAPA-1-like conserved region Lon_C PF05362.8 ETO32651.1 - 0.095 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Lon protease (S16) C-terminal proteolytic domain adh_short PF00106.20 ETO32654.1 - 1.9e-28 99.4 0.0 2.5e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETO32654.1 - 5e-13 49.1 0.0 7.1e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETO32654.1 - 1.5e-12 47.8 0.0 2.1e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase FixQ PF05545.6 ETO32654.1 - 0.53 9.9 6.4 0.29 10.8 0.1 2.5 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF1282 PF06930.7 ETO32655.1 - 0.015 14.9 3.4 0.034 13.7 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) Afi1 PF07792.7 ETO32656.1 - 0.52 10.3 10.7 1 9.3 7.4 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF736 PF05284.7 ETO32657.1 - 0.029 14.2 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF736) DUF1672 PF07901.6 ETO32657.1 - 1.4 7.8 7.4 0.065 12.2 1.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1672) BRAP2 PF07576.7 ETO32658.1 - 0.056 13.0 0.4 3.7 7.1 0.1 2.4 2 0 0 2 2 2 0 BRCA1-associated protein 2 DUF493 PF04359.9 ETO32658.1 - 0.058 13.7 1.6 2.9 8.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF493) Ribosomal_S6 PF01250.12 ETO32658.1 - 0.19 11.5 3.3 0.12 12.1 0.3 2.1 2 0 0 2 2 2 0 Ribosomal protein S6 Herpes_pp85 PF04637.7 ETO32659.1 - 0.089 11.0 0.0 0.1 10.8 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Kinesin PF00225.18 ETO32660.1 - 7.9e-14 51.0 1.6 1.5e-13 50.1 1.1 1.5 1 0 0 1 1 1 1 Kinesin motor domain AAA_16 PF13191.1 ETO32660.1 - 0.014 15.3 0.2 0.047 13.6 0.0 1.9 3 0 0 3 3 3 0 AAA ATPase domain Sulfatase PF00884.18 ETO32661.1 - 4.6e-54 183.6 2.1 9.6e-54 182.6 1.5 1.5 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 ETO32661.1 - 0.011 15.1 0.6 0.073 12.3 0.0 2.4 2 1 1 3 3 3 0 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 ETO32661.1 - 0.018 15.3 0.1 0.12 12.6 0.0 2.2 2 0 0 2 2 2 0 C-terminal region of aryl-sulfatase Eapp_C PF10238.4 ETO32661.1 - 2.7 7.8 11.8 0.09 12.6 1.0 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein PRKCSH PF07915.8 ETO32661.1 - 2.7 8.8 6.1 90 3.9 0.7 3.5 3 0 0 3 3 3 0 Glucosidase II beta subunit-like protein zf-CCCH PF00642.19 ETO32662.1 - 6.3e-08 32.1 4.3 9.7e-08 31.5 3.0 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Transpos_assoc PF13963.1 ETO32663.1 - 0.00067 19.5 1.8 0.0021 18.0 0.4 2.4 2 0 0 2 2 2 1 Transposase-associated domain DUF4187 PF13821.1 ETO32664.1 - 0.037 13.6 0.2 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) V_ATPase_I PF01496.14 ETO32665.1 - 7.7e-19 67.0 5.1 8.6e-19 66.8 3.5 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family MscS_porin PF12795.2 ETO32665.1 - 0.015 14.6 1.6 0.015 14.6 1.1 1.6 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain UPF0449 PF15136.1 ETO32665.1 - 0.23 11.6 3.4 1.3 9.2 0.0 3.4 3 1 1 4 4 4 0 Uncharacterised protein family UPF0449 DUF4200 PF13863.1 ETO32665.1 - 1.5 8.7 11.2 0.06 13.2 3.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF4315 PF14193.1 ETO32665.1 - 1.5 8.7 7.0 1.3 8.9 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) Actin PF00022.14 ETO32667.1 - 3.7e-46 157.3 0.0 1.5e-40 138.8 0.0 2.0 2 0 0 2 2 2 2 Actin Actin PF00022.14 ETO32668.1 - 3.4e-18 65.2 0.1 4e-18 65.0 0.0 1.0 1 0 0 1 1 1 1 Actin Spt20 PF12090.3 ETO32669.1 - 0.051 12.9 0.0 0.08 12.2 0.0 1.2 1 0 0 1 1 1 0 Spt20 family Peptidase_C48 PF02902.14 ETO32673.1 - 7.9e-29 100.8 0.9 7.9e-29 100.8 0.6 2.1 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain GCR1_C PF12550.3 ETO32673.1 - 0.014 15.2 2.6 0.031 14.1 1.2 2.1 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes DUF3319 PF11782.3 ETO32673.1 - 0.1 12.3 1.6 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3319) Peptidase_C57 PF03290.8 ETO32673.1 - 1.5 7.2 14.0 0.085 11.3 0.5 2.5 2 1 1 3 3 3 0 Vaccinia virus I7 processing peptidase NPP PF08384.5 ETO32674.1 - 0.15 11.6 0.4 0.32 10.6 0.2 1.5 1 0 0 1 1 1 0 Pro-opiomelanocortin, N-terminal region Occludin_ELL PF07303.8 ETO32674.1 - 0.39 11.4 7.5 2 9.1 1.1 2.3 2 0 0 2 2 2 0 Occludin homology domain HMG_box PF00505.14 ETO32674.1 - 1.5 9.1 4.4 0.85 9.9 0.5 2.3 2 0 0 2 2 2 0 HMG (high mobility group) box TPX2 PF06886.6 ETO32674.1 - 1.6 8.8 5.1 1 9.4 0.9 2.4 2 1 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) IncA PF04156.9 ETO32674.1 - 2.5 7.6 6.1 4.8 6.7 0.2 2.2 2 0 0 2 2 2 0 IncA protein DUF2422 PF10337.4 ETO32674.1 - 4.8 5.8 5.5 7.2 5.2 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Striatin PF08232.7 ETO32674.1 - 9.7 6.5 12.0 1.8e+02 2.3 0.0 2.4 1 1 1 2 2 2 0 Striatin family XRN_N PF03159.13 ETO32675.1 - 0.018 14.4 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus TP_methylase PF00590.15 ETO32675.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF1086 PF06461.6 ETO32675.1 - 0.18 11.6 2.3 0.24 11.1 1.0 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1086) TRAUB PF08164.7 ETO32675.1 - 1.5 8.9 7.7 3.3 7.8 5.3 1.5 1 0 0 1 1 1 0 Apoptosis-antagonizing transcription factor, C-terminal Telomere_Sde2_2 PF13297.1 ETO32678.1 - 2.3e-23 81.2 0.1 4.1e-23 80.4 0.1 1.4 1 0 0 1 1 1 1 Telomere stability C-terminal Menin PF05053.8 ETO32680.1 - 0.015 13.5 6.7 0.018 13.2 4.7 1.1 1 0 0 1 1 1 0 Menin Pex14_N PF04695.8 ETO32680.1 - 0.019 15.0 1.0 0.025 14.6 0.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2201_N PF13203.1 ETO32680.1 - 0.05 12.7 0.1 0.059 12.5 0.1 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Nop14 PF04147.7 ETO32680.1 - 0.076 10.9 5.6 0.098 10.5 3.9 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.1 ETO32680.1 - 0.13 11.9 1.1 0.21 11.2 0.8 1.4 1 0 0 1 1 1 0 FAM176 family DUF1510 PF07423.6 ETO32680.1 - 0.28 10.5 12.4 0.4 10.0 8.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Osteopontin PF00865.13 ETO32680.1 - 0.44 9.7 16.2 0.6 9.3 11.2 1.1 1 0 0 1 1 1 0 Osteopontin DUF2457 PF10446.4 ETO32680.1 - 0.46 9.1 15.7 0.6 8.7 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF506 PF04720.7 ETO32680.1 - 1.3 8.5 6.1 2 8.0 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF506) RasGEF PF00617.14 ETO32681.1 - 8e-12 45.2 0.4 2.6e-11 43.5 0.0 1.7 1 1 1 2 2 2 1 RasGEF domain Acid_PPase PF12689.2 ETO32681.1 - 0.12 11.9 0.7 0.33 10.5 0.1 1.7 1 1 1 2 2 2 0 Acid Phosphatase Asp PF00026.18 ETO32682.1 - 9.3e-06 25.1 0.0 9.3e-06 25.1 0.0 2.4 2 1 0 2 2 2 1 Eukaryotic aspartyl protease DUF4396 PF14342.1 ETO32682.1 - 0.012 15.6 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4396) RseC_MucC PF04246.7 ETO32682.1 - 0.019 14.5 0.1 0.59 9.7 0.0 2.2 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF3397 PF11877.3 ETO32682.1 - 0.071 13.1 0.1 2.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3397) TAXi_C PF14541.1 ETO32682.1 - 0.099 12.1 1.6 0.23 11.0 0.0 2.2 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Kelch_1 PF01344.20 ETO32683.1 - 6.3e-12 44.8 6.1 0.0081 15.6 0.1 5.8 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 ETO32683.1 - 8.5e-12 44.7 6.4 0.034 14.3 0.1 5.7 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.1 ETO32683.1 - 1.4e-07 31.2 1.5 0.0059 16.5 0.2 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETO32683.1 - 1.1e-06 28.2 7.3 0.0086 15.8 0.0 5.4 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO32683.1 - 0.00014 21.9 7.6 0.36 11.0 0.0 4.8 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO32683.1 - 0.0069 16.1 3.4 2.2 8.1 0.4 4.4 4 1 0 4 4 4 1 Kelch motif RNA_pol PF00940.14 ETO32683.1 - 0.034 12.6 0.0 0.042 12.3 0.0 1.1 1 0 0 1 1 1 0 DNA-dependent RNA polymerase PQQ_3 PF13570.1 ETO32683.1 - 0.3 11.4 2.9 19 5.6 0.1 3.1 3 0 0 3 3 3 0 PQQ-like domain TLD PF07534.11 ETO32684.1 - 1.1e-08 35.1 0.3 3e-08 33.7 0.1 1.9 2 0 0 2 2 2 1 TLD fn3 PF00041.16 ETO32684.1 - 0.0032 17.5 0.2 0.014 15.5 0.0 2.2 2 0 0 2 2 2 1 Fibronectin type III domain Apolipoprotein PF01442.13 ETO32684.1 - 0.0092 15.5 7.8 0.017 14.6 5.4 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain CARD PF00619.16 ETO32684.1 - 0.041 13.7 0.3 0.041 13.7 0.2 2.1 2 0 0 2 2 2 0 Caspase recruitment domain DNA_topoisoIV PF00521.15 ETO32684.1 - 0.087 11.6 7.0 0.14 10.9 4.8 1.3 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A DUF1759 PF03564.10 ETO32684.1 - 0.11 12.3 8.0 0.078 12.7 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) Baculo_PEP_C PF04513.7 ETO32684.1 - 0.11 12.3 1.2 0.2 11.4 0.8 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlgN PF05130.7 ETO32684.1 - 0.37 11.0 10.2 0.65 10.2 7.1 1.4 1 0 0 1 1 1 0 FlgN protein Sulfotransfer_1 PF00685.22 ETO32686.1 - 2e-23 83.0 0.9 2.6e-23 82.6 0.6 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 ETO32686.1 - 0.00033 21.6 0.0 0.00075 20.4 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 ETO32687.1 - 4.5e-16 58.9 0.1 5.2e-16 58.7 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Viral_cys_rich PF08008.7 ETO32687.1 - 0.022 14.3 0.3 0.051 13.1 0.1 1.6 1 1 1 2 2 2 0 Viral cysteine rich HA2 PF04408.18 ETO32687.1 - 0.062 13.3 0.0 0.071 13.1 0.0 1.1 1 0 0 1 1 1 0 Helicase associated domain (HA2) Kelch_1 PF01344.20 ETO32688.1 - 4e-11 42.2 6.1 0.00017 21.0 0.3 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 ETO32688.1 - 2.1e-10 40.2 6.9 0.0012 18.9 0.1 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.1 ETO32688.1 - 1.3e-07 31.4 1.0 0.049 13.6 0.2 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 ETO32688.1 - 2e-06 27.4 0.1 0.003 17.2 0.0 3.4 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO32688.1 - 7.7e-06 25.4 5.1 0.054 13.2 0.1 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 ETO32688.1 - 0.00012 22.1 0.2 0.14 12.3 0.0 3.9 4 0 0 4 4 4 1 Galactose oxidase, central domain WD40 PF00400.27 ETO32689.1 - 1.6e-163 525.5 25.8 2.2e-11 43.1 0.4 16.2 16 0 0 16 16 16 16 WD domain, G-beta repeat Nup160 PF11715.3 ETO32689.1 - 9.7e-17 60.3 32.3 0.073 11.1 0.1 13.1 1 1 12 13 13 13 8 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO32689.1 - 4.3e-08 32.9 2.7 0.023 14.1 0.0 4.4 3 1 2 5 5 5 3 PQQ-like domain DUF1652 PF07865.6 ETO32689.1 - 8.3e-07 28.5 2.0 2.3 7.8 0.0 8.5 9 2 2 11 11 10 1 Protein of unknown function (DUF1652) Nbas_N PF15492.1 ETO32689.1 - 9.8e-07 28.1 12.5 3.3 6.7 0.0 8.7 3 3 5 8 8 8 2 Neuroblastoma-amplified sequence, N terminal Pentapeptide_4 PF13599.1 ETO32689.1 - 5.3e-06 26.1 0.5 2.1e-05 24.2 0.1 2.3 2 0 0 2 2 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETO32689.1 - 4.9e-05 22.4 1.2 0.00019 20.5 1.0 1.8 2 0 0 2 2 2 1 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 ETO32689.1 - 0.00016 21.5 0.7 0.0007 19.4 0.2 2.5 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) DUF1258 PF06869.7 ETO32689.1 - 0.0003 19.9 9.8 1.1 8.3 0.1 6.9 2 2 5 8 8 8 2 Protein of unknown function (DUF1258) Mid2 PF04478.7 ETO32689.1 - 0.00033 20.0 8.7 12 5.3 0.0 8.0 7 2 3 11 11 11 0 Mid2 like cell wall stress sensor Cytochrom_D1 PF02239.11 ETO32689.1 - 0.0045 15.3 6.5 1.1 7.4 0.0 5.6 2 2 2 7 7 7 1 Cytochrome D1 heme domain PD40 PF07676.7 ETO32689.1 - 0.0053 16.3 18.1 13 5.5 0.0 8.5 10 0 0 10 10 10 0 WD40-like Beta Propeller Repeat F420_ligase PF01996.11 ETO32689.1 - 0.015 14.3 0.2 13 4.7 0.1 4.7 3 2 1 4 4 4 0 F420-0:Gamma-glutamyl ligase DUF1513 PF07433.6 ETO32689.1 - 0.024 13.5 0.1 0.6 8.9 0.0 3.3 4 1 0 4 4 4 0 Protein of unknown function (DUF1513) DUF2690 PF10901.3 ETO32689.1 - 0.039 13.9 0.0 1.4e+02 2.4 0.0 5.4 5 2 1 6 6 6 0 Protein of unknown function (DUF2690) NYD-SP28_assoc PF14775.1 ETO32689.1 - 0.14 11.8 13.6 43 3.9 0.0 9.1 13 0 0 13 13 10 0 Sperm tail C-terminal domain Cupin_8 PF13621.1 ETO32690.1 - 1.5e-14 54.1 5.3 1.5e-14 54.1 3.7 1.9 2 1 0 2 2 2 1 Cupin-like domain Cupin_4 PF08007.7 ETO32690.1 - 0.00071 18.9 0.8 0.0016 17.7 0.5 1.9 1 1 0 1 1 1 1 Cupin superfamily protein GPI PF06560.6 ETO32690.1 - 0.0034 16.4 0.1 0.0066 15.4 0.1 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) JmjC PF02373.17 ETO32690.1 - 0.03 14.5 4.7 0.072 13.3 1.0 2.7 2 0 0 2 2 2 0 JmjC domain, hydroxylase ParcG PF10274.4 ETO32691.1 - 6.2e-08 32.7 1.0 0.0017 18.2 0.0 2.9 2 1 1 3 3 3 2 Parkin co-regulated protein DUF3385 PF11865.3 ETO32691.1 - 0.00036 20.5 2.3 0.78 9.6 0.0 3.8 3 1 1 4 4 4 2 Domain of unknown function (DUF3385) MMS19_C PF12460.3 ETO32691.1 - 0.00049 18.9 7.4 0.3 9.7 0.4 3.2 2 1 1 3 3 3 3 RNAPII transcription regulator C-terminal HEAT_2 PF13646.1 ETO32691.1 - 0.0013 18.9 0.1 0.7 10.2 0.0 3.7 2 2 1 3 3 3 1 HEAT repeats HEAT PF02985.17 ETO32691.1 - 0.0019 18.1 0.0 0.049 13.7 0.0 3.2 2 0 0 2 2 2 1 HEAT repeat HEAT_EZ PF13513.1 ETO32691.1 - 0.0056 17.1 0.0 5 7.7 0.0 4.3 4 1 2 6 6 6 1 HEAT-like repeat Pes-10 PF07149.6 ETO32691.1 - 0.0071 15.1 0.5 0.017 13.9 0.4 1.6 1 0 0 1 1 1 1 Pes-10 V-ATPase_H_C PF11698.3 ETO32691.1 - 0.093 12.6 1.2 1.1 9.1 0.4 2.7 2 0 0 2 2 2 0 V-ATPase subunit H Ipi1_N PF12333.3 ETO32691.1 - 0.13 12.2 5.5 1.9 8.4 0.0 3.8 4 1 1 5 5 5 0 Rix1 complex component involved in 60S ribosome maturation Xpo1 PF08389.7 ETO32691.1 - 0.13 12.1 7.9 10 6.0 0.2 5.3 2 2 5 7 7 7 0 Exportin 1-like protein SR-25 PF10500.4 ETO32692.1 - 0.72 9.2 6.6 0.86 9.0 4.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PolyA_pol_RNAbd PF12627.2 ETO32693.1 - 0.082 12.4 0.3 0.23 11.0 0.0 1.8 2 0 0 2 2 2 0 Probable RNA and SrmB- binding site of polymerase A Ribosomal_S27e PF01667.12 ETO32694.1 - 0.12 11.9 0.2 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S27 zf-C2H2_7 PF15269.1 ETO32694.1 - 1 9.2 8.5 3.1 7.7 0.4 2.7 2 1 1 3 3 3 0 Zinc-finger WD40 PF00400.27 ETO32695.1 - 1e-10 41.0 1.0 4.9e-07 29.3 0.2 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat Herpes_UL55 PF04537.7 ETO32695.1 - 0.046 13.1 0.1 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL55 protein BicD PF09730.4 ETO32697.1 - 0.026 12.9 0.0 0.026 12.9 0.0 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D zf-BED PF02892.10 ETO32697.1 - 0.052 13.3 0.8 0.09 12.5 0.6 1.5 1 0 0 1 1 1 0 BED zinc finger Perilipin PF03036.11 ETO32697.1 - 0.053 12.3 0.0 0.058 12.2 0.0 1.0 1 0 0 1 1 1 0 Perilipin family SapB_1 PF05184.10 ETO32697.1 - 0.056 13.2 0.9 0.34 10.8 0.0 2.3 2 0 0 2 2 2 0 Saposin-like type B, region 1 zf-TRAF PF02176.13 ETO32697.1 - 0.26 11.7 2.0 2.7 8.4 1.4 2.2 1 1 0 1 1 1 0 TRAF-type zinc finger DUF536 PF04394.9 ETO32697.1 - 2.2 8.1 6.7 0.67 9.7 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF536 WD40 PF00400.27 ETO32698.1 - 2.4e-26 90.6 1.2 8e-08 31.8 0.1 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat DUF727 PF05303.7 ETO32698.1 - 0.054 13.2 0.3 23 4.8 0.0 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF727) WD40 PF00400.27 ETO32699.1 - 6.8e-56 184.2 15.8 9e-11 41.2 0.3 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO32699.1 - 8.2e-12 44.0 2.0 0.00029 19.1 0.1 4.5 2 1 3 5 5 5 4 Nucleoporin Nup120/160 HAD PF12710.2 ETO32699.1 - 0.14 12.3 1.5 16 5.5 1.0 2.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase TraG-D_C PF12696.2 ETO32700.1 - 4.6 7.1 6.5 0.5 10.2 0.4 2.2 1 1 1 2 2 2 0 TraM recognition site of TraD and TraG B56 PF01603.15 ETO32701.1 - 1.6e-68 231.1 8.1 2.7e-68 230.4 5.6 1.3 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) ABC_membrane PF00664.18 ETO32701.1 - 0.0009 18.7 1.2 0.0017 17.8 0.9 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region OPT PF03169.10 ETO32701.1 - 0.051 11.9 0.8 0.083 11.3 0.6 1.3 1 0 0 1 1 1 0 OPT oligopeptide transporter protein zf-DHHC PF01529.15 ETO32701.1 - 0.68 9.3 10.3 1.6 8.1 7.1 1.6 1 0 0 1 1 1 0 DHHC palmitoyltransferase CAP_GLY PF01302.20 ETO32702.1 - 1e-12 47.5 0.3 2.8e-12 46.1 0.2 1.8 1 0 0 1 1 1 1 CAP-Gly domain Ribonuc_L-PSP PF01042.16 ETO32703.1 - 3.9e-40 136.3 0.1 5.4e-40 135.9 0.1 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP TRAM_LAG1_CLN8 PF03798.11 ETO32705.1 - 0.0001 21.9 1.4 0.00019 21.0 1.0 1.5 1 0 0 1 1 1 1 TLC domain IncA PF04156.9 ETO32705.1 - 0.011 15.2 1.8 0.018 14.6 1.3 1.2 1 0 0 1 1 1 0 IncA protein DUF2347 PF09804.4 ETO32705.1 - 0.038 13.2 6.6 0.053 12.7 4.2 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Vfa1 PF08432.5 ETO32705.1 - 6.7 6.6 20.8 10 6.0 14.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Paramyxo_ncap PF00973.14 ETO32705.1 - 7 5.2 6.4 9 4.8 4.4 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein NPR3 PF03666.8 ETO32705.1 - 7 5.0 11.2 9 4.7 7.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.9 ETO32708.1 - 0.035 12.1 10.2 0.04 11.9 7.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF789 PF05623.7 ETO32708.1 - 0.64 9.4 6.8 0.79 9.1 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF789) Daxx PF03344.10 ETO32708.1 - 5.1 5.4 16.0 6.1 5.2 11.1 1.1 1 0 0 1 1 1 0 Daxx Family Herpes_LMP2 PF07415.6 ETO32708.1 - 8.5 4.8 9.4 9.1 4.7 6.5 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein YL1 PF05764.8 ETO32709.1 - 0.0071 15.9 23.6 0.0084 15.7 16.4 1.1 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.9 ETO32709.1 - 0.22 9.5 22.8 0.29 9.1 15.8 1.2 1 0 0 1 1 1 0 CDC45-like protein ESSS PF10183.4 ETO32709.1 - 1.3 9.4 4.2 3.8 7.9 2.9 1.7 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Apt1 PF10351.4 ETO32709.1 - 4 6.1 22.5 5.3 5.7 15.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Serinc PF03348.10 ETO32709.1 - 4.9 5.7 6.3 10 4.7 4.4 1.5 1 1 0 1 1 1 0 Serine incorporator (Serinc) Ran_BP1 PF00638.13 ETO32710.1 - 0.00093 19.2 1.3 0.01 15.8 0.1 2.6 2 1 0 2 2 2 1 RanBP1 domain KIAA1328 PF15369.1 ETO32710.1 - 3.7 7.2 7.7 4.6 6.9 5.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 PIRT PF15099.1 ETO32711.1 - 0.13 11.5 0.2 0.19 10.9 0.1 1.2 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family ArfGap PF01412.13 ETO32712.1 - 1.3e-30 105.6 1.8 1.6e-30 105.2 0.0 1.7 1 1 1 2 2 2 1 Putative GTPase activating protein for Arf CENP-T PF15511.1 ETO32713.1 - 8.4 5.5 30.6 11 5.1 21.2 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T PhyH PF05721.8 ETO32717.1 - 0.0046 17.0 0.0 0.029 14.4 0.0 2.1 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) HSP70 PF00012.15 ETO32718.1 - 1.7e-19 69.1 0.0 8e-12 43.8 0.0 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 ETO32718.1 - 4.8e-06 25.4 0.0 0.016 13.8 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein PilM_2 PF11104.3 ETO32718.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; Upf2 PF04050.9 ETO32719.1 - 3.8e-06 26.7 28.3 3.8e-06 26.7 19.6 3.0 3 1 1 4 4 4 1 Up-frameshift suppressor 2 Flavokinase PF01687.12 ETO32721.1 - 0.054 13.3 0.6 0.1 12.5 0.4 1.5 1 0 0 1 1 1 0 Riboflavin kinase Aldo_ket_red PF00248.16 ETO32723.1 - 2.9e-26 91.9 0.1 2.6e-25 88.8 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family MIP-T3 PF10243.4 ETO32726.1 - 1.3 7.4 25.1 1.3 7.4 17.4 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF3807 PF12720.2 ETO32726.1 - 7.4 6.7 18.6 9.9 6.2 12.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) MMR_HSR1 PF01926.18 ETO32728.1 - 3.8e-07 30.0 0.2 5.5e-07 29.5 0.2 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 ETO32728.1 - 0.0011 18.2 0.1 0.0019 17.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 ETO32728.1 - 0.016 15.7 0.2 0.048 14.1 0.1 1.9 1 1 0 1 1 1 0 Miro-like protein AIG1 PF04548.11 ETO32728.1 - 0.025 13.6 0.1 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 AIG1 family AAA_18 PF13238.1 ETO32728.1 - 0.038 14.2 0.4 0.062 13.6 0.1 1.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 ETO32728.1 - 0.12 12.6 0.3 0.27 11.5 0.1 1.6 1 1 0 1 1 1 0 ABC transporter Alginate_lyase PF05426.7 ETO32728.1 - 0.15 11.3 1.2 0.19 11.0 0.0 1.6 2 0 0 2 2 2 0 Alginate lyase MIT PF04212.13 ETO32732.1 - 5.7e-18 64.5 1.1 9.4e-18 63.8 0.8 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain VSG_B PF13206.1 ETO32732.1 - 0.012 14.8 4.0 0.011 14.8 2.8 1.0 1 0 0 1 1 1 0 Trypanosomal VSG domain DUF2229 PF09989.4 ETO32732.1 - 0.019 14.4 1.1 0.024 14.0 0.8 1.1 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Nop25 PF09805.4 ETO32732.1 - 0.057 13.4 7.2 0.075 13.0 5.0 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) AAA PF00004.24 ETO32733.1 - 1.2e-36 125.8 0.0 8.3e-35 119.8 0.0 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 ETO32733.1 - 2.7e-17 62.4 0.1 7.5e-17 60.9 0.1 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 ETO32733.1 - 1.7e-06 28.2 0.0 5e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO32733.1 - 4.5e-05 24.2 0.0 0.00012 22.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETO32733.1 - 5.5e-05 23.2 0.0 0.00049 20.1 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 ETO32733.1 - 5.8e-05 22.5 0.0 0.00014 21.2 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein IBN_N PF03810.14 ETO32733.1 - 9.9e-05 22.1 1.0 0.0003 20.6 0.7 1.8 1 0 0 1 1 1 1 Importin-beta N-terminal domain Arch_ATPase PF01637.13 ETO32733.1 - 0.00013 21.7 0.0 0.00029 20.6 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase TIP49 PF06068.8 ETO32733.1 - 0.00013 20.8 0.1 0.00028 19.7 0.0 1.5 2 0 0 2 2 1 1 TIP49 C-terminus AAA_5 PF07728.9 ETO32733.1 - 0.0002 21.0 0.0 0.0019 17.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 ETO32733.1 - 0.00042 20.2 0.0 0.0009 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 ETO32733.1 - 0.00079 19.5 0.2 0.0073 16.4 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 ETO32733.1 - 0.0011 18.8 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 ETO32733.1 - 0.0025 16.9 0.0 0.005 16.0 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ResIII PF04851.10 ETO32733.1 - 0.0027 17.5 0.6 0.016 15.0 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RuvB_N PF05496.7 ETO32733.1 - 0.0036 16.3 0.0 0.011 14.8 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus DUF2075 PF09848.4 ETO32733.1 - 0.004 16.1 0.0 0.0082 15.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.8 ETO32733.1 - 0.0043 16.0 0.1 0.011 14.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_18 PF13238.1 ETO32733.1 - 0.005 17.1 0.0 0.02 15.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 ETO32733.1 - 0.0054 16.3 0.0 0.023 14.3 0.0 2.1 1 1 0 1 1 1 1 NACHT domain AAA_25 PF13481.1 ETO32733.1 - 0.0079 15.6 0.0 0.2 11.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 ETO32733.1 - 0.0089 15.9 0.0 0.086 12.7 0.0 2.5 2 1 0 2 2 1 1 AAA domain Sigma54_activat PF00158.21 ETO32733.1 - 0.013 14.9 0.1 0.042 13.3 0.1 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Torsin PF06309.6 ETO32733.1 - 0.03 14.2 0.0 0.063 13.1 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_24 PF13479.1 ETO32733.1 - 0.036 13.6 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 ETO32733.1 - 0.041 13.1 0.0 0.084 12.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.1 ETO32733.1 - 0.049 13.3 0.0 0.099 12.4 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Cleaved_Adhesin PF07675.6 ETO32733.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Cleaved Adhesin Domain AAA_28 PF13521.1 ETO32733.1 - 0.14 12.0 0.1 0.35 10.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_21 PF13304.1 ETO32733.1 - 0.34 10.8 4.5 3.1 7.6 0.0 3.6 4 0 0 4 4 4 0 AAA domain Cse1 PF08506.5 ETO32734.1 - 1.5e-05 23.7 0.1 2.6e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Cse1 DUF2497 PF10691.4 ETO32734.1 - 0.094 12.6 0.2 0.31 11.0 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2497) PTSIIB_sorb PF03830.10 ETO32736.1 - 0.013 15.3 0.9 0.021 14.7 0.6 1.3 1 0 0 1 1 1 0 PTS system sorbose subfamily IIB component CAP_GLY PF01302.20 ETO32736.1 - 0.064 12.9 0.0 1.5 8.6 0.0 2.8 2 1 0 2 2 2 0 CAP-Gly domain ABC_tran PF00005.22 ETO32737.1 - 4.3e-06 27.0 0.0 8e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_5 PF07728.9 ETO32737.1 - 3.8e-05 23.4 0.0 6.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 ETO32737.1 - 0.00071 19.7 0.0 0.0018 18.4 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 ETO32737.1 - 0.0028 16.8 0.0 0.0049 16.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 ETO32737.1 - 0.0031 17.6 0.0 0.0066 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 ETO32737.1 - 0.0039 17.0 0.0 0.012 15.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 ETO32737.1 - 0.0068 16.8 0.1 0.029 14.8 0.0 2.0 2 1 0 2 2 2 1 Miro-like protein NACHT PF05729.7 ETO32737.1 - 0.015 15.0 0.3 0.17 11.5 0.2 2.3 1 1 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 ETO32737.1 - 0.017 14.8 0.9 0.078 12.6 0.0 2.1 2 1 1 3 3 3 0 Archaeal ATPase DUF4317 PF14199.1 ETO32737.1 - 0.024 13.4 0.8 0.035 12.9 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4317) ATP-synt_ab PF00006.20 ETO32737.1 - 0.024 14.1 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activ_2 PF14532.1 ETO32737.1 - 0.028 14.4 0.0 0.068 13.2 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.1 ETO32737.1 - 0.049 13.9 0.3 0.2 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 ETO32737.1 - 0.057 13.6 0.1 0.12 12.5 0.0 1.8 1 1 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.21 ETO32737.1 - 0.098 12.1 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Rhodanese PF00581.15 ETO32738.1 - 1.6e-07 31.6 0.1 2.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Sec62 PF03839.11 ETO32738.1 - 0.57 9.5 5.1 0.7 9.2 3.5 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 zf-CSL PF05207.8 ETO32739.1 - 0.07 12.6 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 CSL zinc finger CABIT PF12736.2 ETO32739.1 - 0.3 10.0 4.6 0.42 9.5 3.1 1.2 1 1 0 1 1 1 0 Cell-cycle sustaining, positive selection, HGTP_anticodon2 PF12745.2 ETO32739.1 - 0.75 8.8 13.4 0.84 8.7 9.3 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs TFIIE-A_C-term PF11521.3 ETO32739.1 - 1.2 9.1 5.1 1.1 9.2 2.7 1.6 1 1 1 2 2 2 0 C-terminal general transcription factor TFIIE alpha DUF1033 PF06279.6 ETO32739.1 - 3.4 7.5 7.6 7.6 6.3 5.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1033) Myotub-related PF06602.9 ETO32742.1 - 4.2e-117 390.8 0.5 5e-117 390.6 0.4 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 ETO32742.1 - 6.3e-06 25.6 0.3 2e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.15 ETO32742.1 - 5.7e-05 22.7 0.2 0.00013 21.5 0.2 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 ETO32742.1 - 0.00051 20.3 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 ETO32742.1 - 0.0019 17.5 0.8 0.018 14.4 0.0 2.6 3 0 0 3 3 3 1 Tyrosine phosphatase family NHR2 PF08788.6 ETO32742.1 - 0.38 10.2 8.8 21 4.6 0.1 3.6 2 1 1 3 3 3 0 NHR2 domain like WD40 PF00400.27 ETO32743.1 - 1.3e-36 123.1 13.1 1.4e-11 43.8 0.3 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO32743.1 - 5e-07 28.2 0.2 0.044 11.9 0.0 3.7 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO32743.1 - 0.0088 14.8 2.3 0.67 8.6 0.0 2.6 1 1 1 2 2 2 2 Nup133 N terminal like DUF3601 PF12208.3 ETO32743.1 - 0.018 14.9 0.0 0.79 9.7 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3601) PQQ_2 PF13360.1 ETO32743.1 - 0.044 13.2 0.1 0.19 11.1 0.0 1.9 1 1 0 1 1 1 0 PQQ-like domain RPAP2_Rtr1 PF04181.8 ETO32743.1 - 0.55 10.3 4.2 15 5.7 1.0 3.2 3 1 0 3 3 3 0 Rtr1/RPAP2 family RVT_1 PF00078.22 ETO32744.1 - 8.7e-17 61.1 0.0 1.5e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EGF PF00008.22 ETO32745.1 - 0.0015 18.4 6.9 0.0015 18.4 4.8 2.8 4 0 0 4 4 4 1 EGF-like domain EGF_2 PF07974.8 ETO32745.1 - 0.023 14.8 11.0 0.023 14.8 7.6 3.6 3 1 1 4 4 4 0 EGF-like domain Ras PF00071.17 ETO32746.1 - 5e-12 45.5 0.1 4.1e-07 29.5 0.1 2.5 2 0 0 2 2 2 2 Ras family PH PF00169.24 ETO32746.1 - 2.8e-07 30.6 0.1 2.8e-07 30.6 0.1 2.7 3 0 0 3 3 3 1 PH domain C2 PF00168.25 ETO32746.1 - 1.1e-06 28.4 0.0 3.3e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 C2 domain PH_11 PF15413.1 ETO32746.1 - 3.2e-06 27.3 2.1 3.2e-06 27.3 1.5 3.4 3 2 0 3 3 3 1 Pleckstrin homology domain Miro PF08477.8 ETO32746.1 - 0.0048 17.3 0.2 0.073 13.5 0.1 2.7 1 1 0 1 1 1 1 Miro-like protein PS_Dcarbxylase PF02666.10 ETO32747.1 - 1.5e-14 53.8 0.0 2.8e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.1 ETO32747.1 - 0.082 12.5 0.4 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 Biotin-lipoyl like Folate_carrier PF01770.13 ETO32748.1 - 0.082 11.4 1.1 0.094 11.2 0.8 1.1 1 0 0 1 1 1 0 Reduced folate carrier LuxS PF02664.10 ETO32748.1 - 0.23 10.9 2.1 0.39 10.2 1.1 1.6 1 1 1 2 2 2 0 S-Ribosylhomocysteinase (LuxS) APOBEC_C PF05240.9 ETO32750.1 - 0.024 14.0 0.4 0.076 12.4 0.0 2.1 2 0 0 2 2 2 0 APOBEC-like C-terminal domain MGS PF02142.17 ETO32751.1 - 6.1e-13 48.5 0.0 8.2e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 MGS-like domain SLA_LP_auto_ag PF05889.8 ETO32751.1 - 0.00077 18.0 0.0 0.00091 17.7 0.0 1.1 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) REJ PF02010.10 ETO32752.1 - 0.00024 19.5 1.6 0.00027 19.3 1.1 1.0 1 0 0 1 1 1 1 REJ domain GPS PF01825.16 ETO32754.1 - 6.1e-10 39.0 2.4 1.1e-09 38.2 1.6 1.4 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain zf-LITAF-like PF10601.4 ETO32754.1 - 0.04 13.7 2.8 0.07 13.0 2.0 1.3 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain Adeno_E4_ORF3 PF06931.6 ETO32755.1 - 0.014 15.4 0.0 0.049 13.6 0.0 1.9 2 0 0 2 2 2 0 Mastadenovirus E4 ORF3 protein Focal_AT PF03623.8 ETO32755.1 - 0.48 9.9 8.3 0.11 11.9 3.4 1.7 2 0 0 2 2 2 0 Focal adhesion targeting region NPV_P10 PF05531.7 ETO32755.1 - 0.9 9.8 7.1 3.5 7.9 1.1 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1845 PF08900.6 ETO32755.1 - 0.97 8.6 6.4 4 6.6 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1845) Baculo_PEP_C PF04513.7 ETO32755.1 - 1.3 8.8 10.4 1.3 8.8 2.9 3.3 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Allexi_40kDa PF05549.6 ETO32755.1 - 9.9 5.3 11.1 0.91 8.7 3.7 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein SKG6 PF08693.5 ETO32757.1 - 1.5e-06 27.3 1.2 1.5e-06 27.3 0.8 2.2 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 ETO32757.1 - 0.04 13.3 0.5 0.079 12.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) GAPT PF11770.3 ETO32757.1 - 0.12 12.0 1.2 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) MLANA PF14991.1 ETO32757.1 - 0.32 11.0 2.8 0.27 11.2 0.2 2.1 2 1 0 2 2 2 0 Protein melan-A PIRT PF15099.1 ETO32757.1 - 0.35 10.0 3.1 1.8 7.7 0.0 2.9 3 0 0 3 3 3 0 Phosphoinositide-interacting protein family RRM_1 PF00076.17 ETO32758.1 - 1.8e-05 24.2 0.0 6.6e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO32758.1 - 0.0015 18.2 0.0 0.0034 17.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO32758.1 - 0.044 13.7 0.0 0.23 11.4 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 ETO32759.1 - 2.2e-70 230.1 18.8 2.6e-13 49.2 0.1 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO32759.1 - 2.1e-10 39.4 5.5 0.0014 16.8 0.1 4.7 1 1 4 5 5 5 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO32759.1 - 3.1e-05 22.4 0.3 0.005 15.1 0.0 2.9 1 1 2 3 3 3 1 Cytochrome D1 heme domain Kelch_6 PF13964.1 ETO32759.1 - 0.0034 17.4 6.1 12 6.3 0.0 5.3 5 1 0 5 5 5 1 Kelch motif PQQ_2 PF13360.1 ETO32759.1 - 0.0041 16.6 0.2 0.068 12.6 0.0 2.8 2 1 0 2 2 2 1 PQQ-like domain DUF727 PF05303.7 ETO32759.1 - 0.011 15.5 0.9 13 5.5 0.0 4.4 4 1 1 5 5 5 0 Protein of unknown function (DUF727) DUF1797 PF08796.5 ETO32759.1 - 0.016 15.0 0.0 5.6 6.9 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1797) Resistin PF06954.6 ETO32759.1 - 0.022 15.0 0.1 8.1 6.7 0.0 3.5 2 1 1 3 3 3 0 Resistin Kelch_1 PF01344.20 ETO32759.1 - 0.027 13.9 10.1 6.5 6.3 0.0 5.2 6 0 0 6 6 6 0 Kelch motif Kelch_5 PF13854.1 ETO32759.1 - 0.035 14.0 3.4 2.2 8.3 0.0 3.2 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.1 ETO32759.1 - 0.079 12.7 4.8 2 8.2 0.1 4.5 5 0 0 5 5 5 0 Galactose oxidase, central domain PD40 PF07676.7 ETO32759.1 - 0.68 9.6 7.2 11 5.8 0.1 5.0 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat DUF159 PF02586.9 ETO32760.1 - 6.6e-48 162.9 0.4 1.2e-47 162.1 0.3 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Metallophos PF00149.23 ETO32761.1 - 0.0048 16.3 0.0 0.0074 15.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2259 PF10016.4 ETO32761.1 - 0.017 14.8 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Predicted secreted protein (DUF2259) Flu_NP PF00506.13 ETO32761.1 - 0.034 12.6 0.3 0.13 10.7 0.1 1.8 2 0 0 2 2 2 0 Influenza virus nucleoprotein Cnd1 PF12717.2 ETO32762.1 - 7e-05 22.7 1.1 0.0032 17.3 0.7 2.3 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 ETO32762.1 - 7.5e-05 22.4 0.3 0.0035 17.2 0.0 3.4 4 1 0 4 4 4 1 HEAT repeat DUF3554 PF12074.3 ETO32762.1 - 0.0097 15.3 0.1 0.012 15.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3554) Condensin2nSMC PF12422.3 ETO32762.1 - 0.039 13.7 0.1 0.053 13.2 0.1 1.2 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit HEAT_EZ PF13513.1 ETO32762.1 - 0.042 14.3 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 HEAT-like repeat MMS19_N PF14500.1 ETO32762.1 - 0.055 12.7 0.2 0.11 11.7 0.1 1.5 1 1 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II UME PF08064.8 ETO32762.1 - 0.06 13.3 0.1 0.23 11.3 0.0 1.9 1 1 1 2 2 2 0 UME (NUC010) domain HEAT_2 PF13646.1 ETO32762.1 - 0.063 13.5 0.0 0.13 12.5 0.0 1.4 1 1 0 1 1 1 0 HEAT repeats FANCI_S1 PF14675.1 ETO32762.1 - 0.09 12.1 0.6 0.13 11.6 0.4 1.3 1 1 0 1 1 1 0 FANCI solenoid 1 DUF3944 PF13099.1 ETO32762.1 - 0.78 9.2 0.1 0.78 9.2 0.0 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF3944) Peptidase_M3 PF01432.15 ETO32763.1 - 3.8e-38 131.6 0.1 4.2e-38 131.5 0.1 1.0 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M3 PF01432.15 ETO32764.1 - 1.1e-09 37.9 0.1 1.5e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M3 DEP PF00610.16 ETO32765.1 - 5.4e-16 58.0 0.0 8e-16 57.5 0.0 1.3 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF1198 PF06711.6 ETO32768.1 - 0.016 15.0 0.0 0.044 13.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1198) ETRAMP PF09716.5 ETO32769.1 - 0.07 13.0 3.3 2.5 8.1 0.0 3.8 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Tetraspannin PF00335.15 ETO32769.1 - 0.24 10.6 4.8 0.23 10.7 1.0 2.3 2 1 0 2 2 2 0 Tetraspanin family ABC2_membrane_3 PF12698.2 ETO32769.1 - 1.1 8.2 7.5 0.16 10.9 0.6 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein WD40 PF00400.27 ETO32770.1 - 3e-40 134.6 9.8 5.1e-12 45.1 0.1 4.0 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO32770.1 - 5.9e-05 21.4 0.9 0.11 10.6 0.1 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO32770.1 - 0.00048 18.9 4.3 0.37 9.4 0.1 3.5 1 1 2 3 3 3 2 Nup133 N terminal like Hira PF07569.6 ETO32770.1 - 0.0064 15.7 0.4 0.5 9.5 0.0 2.4 1 1 2 3 3 3 2 TUP1-like enhancer of split PQQ_2 PF13360.1 ETO32770.1 - 0.0092 15.4 0.0 0.042 13.3 0.0 1.7 1 1 1 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO32770.1 - 0.023 13.0 0.1 0.21 9.8 0.0 1.9 1 1 0 1 1 1 0 Cytochrome D1 heme domain TFIIIC_delta PF12657.2 ETO32770.1 - 0.031 13.9 0.7 0.078 12.6 0.5 1.8 1 1 0 1 1 1 0 Transcription factor IIIC subunit delta N-term DUF4221 PF13970.1 ETO32770.1 - 0.049 12.9 0.7 0.1 11.8 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4221) Ricin_B_lectin PF00652.17 ETO32770.1 - 0.47 10.5 3.7 0.96 9.4 1.1 2.0 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain DUF4557 PF15101.1 ETO32771.1 - 0.3 10.9 2.7 0.38 10.5 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Hid1 PF12722.2 ETO32771.1 - 2.6 5.5 7.5 2.6 5.6 5.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Suf PF05843.9 ETO32771.1 - 3.8 7.1 9.1 5.1 6.7 6.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.11 ETO32771.1 - 3.8 7.3 7.1 4.3 7.1 5.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ndc1_Nup PF09531.5 ETO32771.1 - 6.1 5.1 9.2 7 4.9 6.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SRP-alpha_N PF04086.8 ETO32771.1 - 6.6 6.0 14.8 7.6 5.8 10.3 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF3807 PF12720.2 ETO32771.1 - 7.2 6.7 9.6 9.3 6.3 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) CMV_1a PF12467.3 ETO32771.1 - 8 6.8 10.6 11 6.3 7.3 1.2 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family DUF3464 PF11947.3 ETO32771.1 - 8.4 5.8 10.7 11 5.4 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Peptidase_M24 PF00557.19 ETO32772.1 - 7.1e-43 146.6 0.0 8.8e-43 146.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DivIC PF04977.10 ETO32773.1 - 0.0074 15.7 0.6 0.0074 15.7 0.4 2.8 1 1 1 2 2 2 1 Septum formation initiator DUF4618 PF15397.1 ETO32773.1 - 0.02 14.2 8.2 0.8 8.9 5.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) RsbRD_N PF14361.1 ETO32773.1 - 0.022 15.2 1.8 0.4 11.1 0.1 2.9 2 1 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain Tropomyosin PF00261.15 ETO32773.1 - 0.024 13.7 13.4 0.043 12.9 9.3 1.3 1 1 0 1 1 1 0 Tropomyosin LXG PF04740.7 ETO32773.1 - 0.03 14.1 4.5 0.088 12.5 2.6 1.9 1 1 0 2 2 2 0 LXG domain of WXG superfamily HALZ PF02183.13 ETO32773.1 - 0.04 13.6 0.5 0.04 13.6 0.3 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF1206 PF06724.6 ETO32773.1 - 0.052 13.2 1.8 6.7 6.5 0.7 2.3 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1206) DUF3106 PF11304.3 ETO32773.1 - 0.15 12.4 5.3 3.9 7.9 2.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) DUF4446 PF14584.1 ETO32773.1 - 0.33 10.7 5.4 1.6 8.5 0.1 2.7 1 1 3 4 4 4 0 Protein of unknown function (DUF4446) TMF_TATA_bd PF12325.3 ETO32773.1 - 0.36 10.5 10.6 0.29 10.8 6.3 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 ETO32773.1 - 0.78 9.3 12.5 0.56 9.7 6.8 1.9 1 1 1 2 2 2 0 IncA protein DivIVA PF05103.8 ETO32773.1 - 1.6 8.8 10.9 8 6.5 0.5 2.6 1 1 2 3 3 3 0 DivIVA protein DUF972 PF06156.8 ETO32773.1 - 2.1 8.7 11.8 4.4 7.6 3.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF904 PF06005.7 ETO32773.1 - 2.7 8.3 12.2 1.6 9.1 1.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Fzo_mitofusin PF04799.8 ETO32773.1 - 2.8 7.3 6.1 5.6 6.3 3.8 1.8 1 1 0 1 1 1 0 fzo-like conserved region Atg14 PF10186.4 ETO32773.1 - 5.2 5.9 8.5 7.8 5.3 5.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 ETO32773.1 - 5.5 5.9 13.6 0.54 9.2 5.4 1.7 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF912 PF06024.7 ETO32775.1 - 0.011 15.7 7.6 0.026 14.5 5.3 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ATG27 PF09451.5 ETO32775.1 - 0.016 14.4 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 DUF2615 PF11027.3 ETO32775.1 - 0.049 13.5 1.3 0.089 12.7 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) DUF1183 PF06682.7 ETO32775.1 - 0.051 13.1 0.1 0.083 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Shisa PF13908.1 ETO32775.1 - 0.062 13.4 0.3 0.11 12.6 0.2 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF3753 PF12575.3 ETO32775.1 - 0.086 12.6 3.6 0.23 11.2 2.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) ETRAMP PF09716.5 ETO32775.1 - 0.43 10.5 3.8 0.25 11.3 0.7 2.0 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) CAAD PF14159.1 ETO32775.1 - 2.9 7.5 5.6 5.4 6.7 0.7 2.5 2 1 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Herpes_UL51 PF04540.8 ETO32776.1 - 0.089 12.3 0.2 0.21 11.1 0.0 1.7 1 1 1 2 2 2 0 Herpesvirus UL51 protein RP-C_C PF11800.3 ETO32776.1 - 1.3 8.6 4.2 1.9 8.1 2.8 1.4 1 1 0 1 1 1 0 Replication protein C C-terminal region Med14 PF08638.6 ETO32777.1 - 1.4e-09 37.5 0.0 1.2e-06 27.9 0.0 2.3 2 0 0 2 2 2 2 Mediator complex subunit MED14 DUF1510 PF07423.6 ETO32777.1 - 4.9e-05 22.7 6.3 0.00013 21.4 3.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) U79_P34 PF03064.11 ETO32777.1 - 0.00094 18.7 7.4 0.0012 18.3 5.2 1.2 1 0 0 1 1 1 1 HSV U79 / HCMV P34 Peptidase_S49_N PF08496.5 ETO32777.1 - 0.069 12.9 10.1 0.21 11.3 5.2 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal BPL_N PF09825.4 ETO32777.1 - 0.15 10.8 0.0 0.15 10.8 0.0 1.9 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal CDC45 PF02724.9 ETO32777.1 - 5.7 4.8 12.9 8.1 4.3 8.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Spc97_Spc98 PF04130.8 ETO32779.1 - 6.1e-29 100.7 0.1 9.7e-29 100.0 0.0 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family YagB_YeeU_YfjZ PF06154.6 ETO32779.1 - 0.09 13.0 0.4 0.5 10.6 0.1 2.2 2 0 0 2 2 2 0 YagB/YeeU/YfjZ family priB_priC PF07445.7 ETO32781.1 - 0.061 12.7 0.2 0.082 12.3 0.1 1.2 1 0 0 1 1 1 0 Primosomal replication protein priB and priC PK_C PF02887.11 ETO32782.1 - 1.1e-23 82.9 1.9 2.5e-23 81.8 1.3 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain DRTGG PF07085.7 ETO32782.1 - 0.042 13.4 0.7 3.5 7.2 0.0 2.6 2 0 0 2 2 2 0 DRTGG domain DUF3357 PF11837.3 ETO32782.1 - 0.083 12.7 0.2 0.083 12.7 0.1 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3357) Conotoxin PF02950.12 ETO32782.1 - 0.84 10.4 12.0 3.7 8.4 0.0 3.6 3 0 0 3 3 3 0 Conotoxin SURF2 PF05477.6 ETO32782.1 - 2.5 7.1 15.0 5.2 6.1 10.4 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Hydrolase_like2 PF13246.1 ETO32783.1 - 3.7e-09 36.4 0.8 1.2e-08 34.7 0.3 2.3 1 1 1 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 ETO32783.1 - 3.8e-07 29.3 0.0 7.2e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Flavodoxin_4 PF12682.2 ETO32783.1 - 0.039 13.3 0.2 0.088 12.1 0.1 1.5 1 0 0 1 1 1 0 Flavodoxin Nop14 PF04147.7 ETO32783.1 - 0.19 9.6 45.9 0.3 8.9 31.8 1.2 1 0 0 1 1 1 0 Nop14-like family MbeD_MobD PF04899.7 ETO32784.1 - 0.0045 16.8 0.7 0.29 11.0 0.0 2.5 2 0 0 2 2 2 1 MbeD/MobD like HALZ PF02183.13 ETO32784.1 - 0.05 13.3 3.3 0.15 11.8 1.7 2.3 2 1 0 2 2 2 0 Homeobox associated leucine zipper Osmo_CC PF08946.5 ETO32784.1 - 0.36 10.9 3.2 0.35 10.9 0.2 2.5 3 0 0 3 3 3 0 Osmosensory transporter coiled coil Phage_GP20 PF06810.6 ETO32784.1 - 1.2 8.6 7.2 1.1 8.7 3.4 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 GrpE PF01025.14 ETO32784.1 - 1.3 8.5 8.3 1.7 8.1 0.1 2.3 2 1 0 2 2 2 0 GrpE DUF2899 PF11449.3 ETO32785.1 - 0.00011 21.5 6.7 0.0024 17.1 1.0 1.6 1 1 1 2 2 2 2 Protein of unknown function (DUF2899) DUF1673 PF07895.6 ETO32785.1 - 0.00016 21.2 0.3 0.00022 20.8 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1673) DUF373 PF04123.8 ETO32785.1 - 0.0042 16.1 2.3 0.0053 15.8 1.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF373) DUF3671 PF12420.3 ETO32785.1 - 0.0086 16.0 2.9 0.31 11.0 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function DUF3169 PF11368.3 ETO32785.1 - 0.011 15.0 4.1 0.058 12.5 2.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) Tetraspannin PF00335.15 ETO32785.1 - 0.015 14.6 2.2 0.022 14.0 1.5 1.4 1 0 0 1 1 1 0 Tetraspanin family DUF4064 PF13273.1 ETO32785.1 - 0.027 14.5 7.1 0.035 14.2 2.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) PMP22_Claudin PF00822.15 ETO32785.1 - 0.028 14.0 0.5 0.028 14.0 0.4 1.8 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin family Tic20 PF09685.5 ETO32785.1 - 0.11 12.5 7.9 0.82 9.6 2.7 2.1 2 0 0 2 2 2 0 Tic20-like protein DUF2207 PF09972.4 ETO32785.1 - 1.2 7.5 6.3 5.7 5.4 1.6 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF1056 PF06341.6 ETO32785.1 - 4.7 7.3 14.8 16 5.6 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1056) RCC1 PF00415.13 ETO32787.1 - 1.2e-16 60.6 14.0 6.9e-05 22.9 0.3 5.4 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO32787.1 - 2.5e-10 39.6 17.3 1.2e-05 24.7 0.6 4.8 5 1 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat Kelch_6 PF13964.1 ETO32787.1 - 0.037 14.1 4.0 1.4 9.2 0.0 3.7 3 0 0 3 3 3 0 Kelch motif WD40 PF00400.27 ETO32788.1 - 1.4e-05 24.7 2.1 9.4e-05 22.1 0.3 2.4 2 1 0 2 2 2 1 WD domain, G-beta repeat Peptidase_C14 PF00656.17 ETO32789.1 - 2.8e-09 37.0 0.3 3.4e-09 36.7 0.2 1.1 1 0 0 1 1 1 1 Caspase domain WD40 PF00400.27 ETO32790.1 - 1e-48 161.5 13.5 9.1e-11 41.2 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO32790.1 - 7.3e-11 40.8 4.9 0.019 13.1 0.0 4.9 1 1 4 5 5 5 5 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO32790.1 - 0.006 16.3 5.3 15 5.2 0.0 4.2 2 2 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A HAD PF12710.2 ETO32790.1 - 0.057 13.5 0.8 10 6.2 0.0 2.9 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF3810 PF12725.2 ETO32792.1 - 0.08 11.8 1.9 0.15 10.8 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) CUE PF02845.11 ETO32793.1 - 3.4e-09 36.0 0.4 3.7e-06 26.2 0.0 2.8 2 0 0 2 2 2 2 CUE domain DMA PF03474.9 ETO32793.1 - 0.1 12.4 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 DMRTA motif Senescence_reg PF04520.8 ETO32793.1 - 5.4 7.5 12.6 0.2 12.1 3.8 2.0 2 0 0 2 2 2 0 Senescence regulator Vfa1 PF08432.5 ETO32794.1 - 0.00092 19.2 3.1 0.0011 19.0 2.2 1.2 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Atrophin-1 PF03154.10 ETO32794.1 - 0.0017 16.6 1.2 0.002 16.4 0.8 1.0 1 0 0 1 1 1 1 Atrophin-1 family Tim54 PF11711.3 ETO32794.1 - 0.0072 14.9 1.2 0.0085 14.7 0.8 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 SPOC PF07744.8 ETO32794.1 - 0.03 14.7 0.0 0.066 13.7 0.0 1.6 1 0 0 1 1 1 0 SPOC domain Spore_coat_CotO PF14153.1 ETO32794.1 - 0.045 13.2 7.2 0.058 12.8 5.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO OATP PF03137.15 ETO32794.1 - 0.29 9.1 2.0 0.32 8.9 1.4 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family UPF0542 PF15086.1 ETO32794.1 - 0.51 10.0 6.0 0.84 9.4 4.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 OAD_gamma PF04277.8 ETO32794.1 - 1.1 9.7 6.3 1.9 8.8 4.4 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Peptidase_S49_N PF08496.5 ETO32794.1 - 2.1 8.1 7.3 3 7.6 5.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal COX16 PF14138.1 ETO32794.1 - 3 8.0 7.6 5.5 7.2 5.2 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 Kelch_6 PF13964.1 ETO32795.1 - 2e-07 30.8 3.6 0.0011 19.0 0.1 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 ETO32795.1 - 2.7e-06 27.3 0.2 0.056 13.6 0.0 3.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO32795.1 - 3.1e-05 23.7 3.6 0.041 13.8 0.5 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 ETO32795.1 - 0.00088 18.7 7.5 0.044 13.3 0.6 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 ETO32795.1 - 0.0071 16.0 3.8 0.23 11.2 0.0 3.6 4 0 0 4 4 4 1 Kelch motif DUF4201 PF13870.1 ETO32795.1 - 0.038 13.4 6.8 0.081 12.3 4.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) PSP94 PF05825.6 ETO32795.1 - 0.097 12.9 5.7 0.53 10.5 0.3 2.9 2 0 0 2 2 2 0 Beta-microseminoprotein (PSP-94) XhlA PF10779.4 ETO32795.1 - 0.93 9.4 9.4 3.1 7.7 6.3 2.0 1 1 0 1 1 1 0 Haemolysin XhlA AAA_27 PF13514.1 ETO32795.1 - 1.7 6.2 5.8 2.3 5.7 4.0 1.0 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 ETO32796.1 - 1.8e-72 236.8 13.5 1.6e-12 46.7 0.1 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO32796.1 - 1.2e-05 25.1 0.4 0.12 12.0 0.0 3.3 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO32796.1 - 0.00045 18.4 5.6 0.76 7.8 0.4 4.5 1 1 2 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO32796.1 - 0.0047 16.4 0.3 1.9 7.8 0.1 2.8 2 1 1 3 3 3 2 PQQ-like domain Nbas_N PF15492.1 ETO32796.1 - 0.015 14.4 0.7 0.48 9.4 0.1 2.5 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 ETO32796.1 - 0.021 13.1 0.3 4.4 5.5 0.0 2.7 2 1 0 3 3 3 0 Cytochrome D1 heme domain PD40 PF07676.7 ETO32796.1 - 0.084 12.5 4.5 6.2 6.6 0.1 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat rpo30_N PF12410.3 ETO32796.1 - 0.1 12.2 0.1 2.5 7.7 0.0 2.4 2 0 0 2 2 2 0 Poxvirus DNA dependent RNA polymerase 30kDa subunit WD40 PF00400.27 ETO32797.1 - 3.1e-56 185.3 11.9 2.3e-10 39.9 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO32797.1 - 5.4e-05 21.5 1.7 0.55 8.2 0.0 3.8 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO32797.1 - 9.8e-05 20.8 0.0 0.15 10.3 0.0 2.9 1 1 2 3 3 3 3 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 ETO32797.1 - 0.1 11.9 5.5 2.2 7.6 0.0 4.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature PD40 PF07676.7 ETO32797.1 - 0.2 11.3 5.7 33 4.2 0.0 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Kelch_6 PF13964.1 ETO32798.1 - 0.072 13.2 5.3 1.1 9.5 0.0 4.4 4 1 1 5 5 5 0 Kelch motif Nbs1_C PF08599.5 ETO32798.1 - 0.15 11.9 1.8 0.62 10.0 0.2 2.3 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 Kelch_1 PF01344.20 ETO32798.1 - 7.5 6.1 8.2 10 5.7 0.4 3.6 4 0 0 4 4 4 0 Kelch motif DUF737 PF05300.6 ETO32799.1 - 0.93 9.4 10.7 0.95 9.3 7.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF737) BLVR PF06375.6 ETO32799.1 - 1.1 9.0 17.2 1.1 9.0 11.9 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) DUF4615 PF15393.1 ETO32799.1 - 1.4 9.1 11.6 1.4 9.1 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) RHD PF00554.17 ETO32799.1 - 1.5 8.5 6.7 1.4 8.6 4.7 1.0 1 0 0 1 1 1 0 Rel homology domain (RHD) BRF1 PF07741.8 ETO32799.1 - 2.1 8.6 13.8 2.8 8.2 9.6 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain SR-25 PF10500.4 ETO32799.1 - 3.2 7.1 17.8 3.3 7.0 12.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AAA PF00004.24 ETO32802.1 - 1e-09 38.6 5.3 0.0013 18.8 3.5 3.2 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETO32802.1 - 3e-08 33.5 1.3 0.0031 17.2 0.5 3.7 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 ETO32802.1 - 2.5e-07 30.6 8.5 3.8e-06 26.7 1.3 3.0 3 0 0 3 3 3 1 Archaeal ATPase AAA_22 PF13401.1 ETO32802.1 - 3.3e-07 30.5 1.4 0.0076 16.3 0.2 3.0 2 2 0 2 2 2 2 AAA domain ABC_tran PF00005.22 ETO32802.1 - 4.3e-06 27.0 1.7 1.4e-05 25.3 0.1 2.6 3 0 0 3 3 2 1 ABC transporter AAA_16 PF13191.1 ETO32802.1 - 1.5e-05 25.0 0.1 0.0043 17.0 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain DUF258 PF03193.11 ETO32802.1 - 0.00012 21.3 0.0 0.00078 18.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_2 PF07724.9 ETO32802.1 - 0.00022 21.1 1.0 0.0075 16.1 0.6 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) PduV-EutP PF10662.4 ETO32802.1 - 0.00071 19.0 0.1 0.008 15.6 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 ETO32802.1 - 0.0009 18.2 0.0 0.0029 16.5 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 ETO32802.1 - 0.0021 18.0 2.0 0.15 12.0 1.9 3.0 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.1 ETO32802.1 - 0.0037 17.2 0.0 0.0037 17.2 0.0 2.6 3 1 0 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.1 ETO32802.1 - 0.0045 17.0 0.0 0.23 11.4 0.0 3.0 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.1 ETO32802.1 - 0.0048 17.1 1.2 0.033 14.4 0.7 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 ETO32802.1 - 0.0052 16.2 0.1 1.3 8.3 0.0 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_17 PF13207.1 ETO32802.1 - 0.0074 17.0 0.4 0.054 14.3 0.1 2.6 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 ETO32802.1 - 0.0082 15.3 0.5 2.8 7.0 0.0 3.4 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI DUF2252 PF10009.4 ETO32802.1 - 0.0092 14.9 2.5 0.016 14.0 1.7 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2252) Sigma54_activat PF00158.21 ETO32802.1 - 0.011 15.2 0.1 0.69 9.3 0.0 3.3 4 0 0 4 4 4 0 Sigma-54 interaction domain AAA_14 PF13173.1 ETO32802.1 - 0.014 15.3 11.5 0.45 10.4 2.0 4.2 5 1 0 5 5 2 0 AAA domain Miro PF08477.8 ETO32802.1 - 0.014 15.8 3.6 0.027 14.9 0.6 2.9 2 1 0 2 2 2 0 Miro-like protein Viral_helicase1 PF01443.13 ETO32802.1 - 0.018 14.6 0.2 1 8.8 0.1 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 ETO32802.1 - 0.033 14.3 0.0 1.1 9.4 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA_3 PF07726.6 ETO32802.1 - 0.035 13.7 0.0 4.1 7.0 0.0 3.4 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 ETO32802.1 - 0.055 13.1 0.1 0.36 10.4 0.1 2.3 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 ETO32802.1 - 0.055 13.0 0.1 0.32 10.6 0.0 2.3 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 ETO32802.1 - 0.058 12.2 0.3 0.33 9.7 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.1 ETO32802.1 - 0.21 11.3 0.0 16 5.3 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain MCM PF00493.18 ETO32802.1 - 0.37 9.5 4.8 1.1 8.0 0.0 3.1 4 0 0 4 4 3 0 MCM2/3/5 family PMSR PF01625.16 ETO32804.1 - 0.02 14.8 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 Peptide methionine sulfoxide reductase ERG2_Sigma1R PF04622.7 ETO32805.1 - 0.053 12.7 0.2 6.2 6.0 0.1 2.6 2 0 0 2 2 2 0 ERG2 and Sigma1 receptor like protein DUF912 PF06024.7 ETO32805.1 - 0.62 10.1 13.7 1.1 9.3 3.2 3.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) priB_priC PF07445.7 ETO32806.1 - 0.0019 17.6 0.3 0.0036 16.8 0.2 1.4 1 0 0 1 1 1 1 Primosomal replication protein priB and priC Folliculin PF11704.3 ETO32806.1 - 0.0048 16.5 2.9 0.0091 15.5 1.7 1.7 1 1 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport PID_2 PF14719.1 ETO32806.1 - 0.0058 16.2 0.6 0.0058 16.2 0.4 2.1 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) Kelch_6 PF13964.1 ETO32807.1 - 2.1e-08 33.9 2.9 0.0046 17.0 0.3 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO32807.1 - 2.3e-08 33.4 5.7 6.4e-07 28.8 0.6 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO32807.1 - 5e-07 29.2 2.4 0.011 15.4 0.2 4.2 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 ETO32807.1 - 2e-05 24.4 4.4 0.012 15.5 0.9 4.2 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 ETO32807.1 - 4.5e-05 23.4 0.2 0.00066 19.7 0.1 2.9 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO32807.1 - 0.01 15.5 1.5 0.68 9.7 0.3 3.2 2 1 1 3 3 3 0 Galactose oxidase, central domain CLASP_N PF12348.3 ETO32809.1 - 0.041 13.2 0.0 2.5 7.3 0.0 2.1 2 0 0 2 2 2 0 CLASP N terminal FANCI_S3 PF14677.1 ETO32810.1 - 0.0088 15.4 1.7 0.025 13.9 0.5 2.1 1 1 1 2 2 2 1 FANCI solenoid 3 DUF3439 PF11921.3 ETO32810.1 - 0.8 9.4 5.4 2 8.1 3.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF3446 PF11928.3 ETO32810.1 - 0.88 9.8 17.0 2.2 8.5 4.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) SoxE PF06525.6 ETO32810.1 - 1.4 8.1 6.8 2 7.6 0.1 2.2 2 0 0 2 2 2 0 Sulfocyanin (SoxE) PI3Ka PF00613.15 ETO32812.1 - 1.4e-47 161.2 2.8 2.5e-47 160.4 1.9 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 ETO32812.1 - 2.8e-36 125.1 0.1 9.9e-36 123.3 0.1 2.0 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 ETO32812.1 - 4.2e-14 52.5 0.1 1.1e-13 51.2 0.1 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.13 ETO32812.1 - 7.4e-11 41.9 1.4 2e-10 40.5 0.0 2.4 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain DUF4293 PF14126.1 ETO32813.1 - 0.0085 16.0 0.4 0.012 15.5 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4293) WD40 PF00400.27 ETO32814.1 - 5e-74 241.7 14.5 5.8e-12 45.0 0.0 7.0 7 0 0 7 7 7 7 WD domain, G-beta repeat PQQ_2 PF13360.1 ETO32814.1 - 1.4e-10 41.0 1.2 2.4e-05 23.9 0.1 2.3 1 1 1 2 2 2 2 PQQ-like domain eIF2A PF08662.6 ETO32814.1 - 1.8e-10 40.8 0.6 0.00017 21.3 0.0 3.5 1 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO32814.1 - 6.3e-08 31.2 9.9 0.057 11.5 0.1 5.7 1 1 4 5 5 5 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO32814.1 - 7.4e-07 27.7 0.1 0.00022 19.6 0.0 2.5 1 1 2 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO32814.1 - 1.3e-05 24.1 7.0 0.41 9.3 0.0 4.9 1 1 4 5 5 5 3 Nup133 N terminal like Resistin PF06954.6 ETO32814.1 - 0.00014 22.0 0.5 6 7.2 0.0 4.1 3 1 2 5 5 4 1 Resistin Nbas_N PF15492.1 ETO32814.1 - 0.00085 18.5 0.2 0.29 10.2 0.0 2.8 1 1 2 3 3 3 1 Neuroblastoma-amplified sequence, N terminal PQQ PF01011.16 ETO32814.1 - 0.0015 17.9 0.0 0.075 12.6 0.0 3.2 3 0 0 3 3 3 1 PQQ enzyme repeat DUF1258 PF06869.7 ETO32814.1 - 0.0047 16.0 3.8 0.42 9.6 0.3 3.5 1 1 3 4 4 4 2 Protein of unknown function (DUF1258) PD40 PF07676.7 ETO32814.1 - 0.0081 15.8 8.1 2 8.1 0.1 4.4 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 ETO32814.1 - 0.027 13.0 0.0 6.8 5.1 0.0 3.0 1 1 2 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF1652 PF07865.6 ETO32814.1 - 0.066 12.8 0.0 6 6.5 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1652) Proteasome_A_N PF10584.4 ETO32814.1 - 0.58 9.5 7.7 21 4.5 0.4 3.6 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Exostosin PF03016.10 ETO32816.1 - 1.3e-06 27.6 0.0 3.1e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 Exostosin family Kelch_6 PF13964.1 ETO32817.1 - 1.3e-05 25.1 9.9 0.0074 16.4 0.2 4.6 6 0 0 6 6 6 2 Kelch motif Kelch_5 PF13854.1 ETO32817.1 - 0.0023 17.8 1.2 1 9.3 0.0 3.7 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO32817.1 - 0.0043 16.7 5.1 12 5.8 0.1 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO32817.1 - 0.072 12.6 0.1 0.072 12.6 0.0 4.3 4 1 0 4 4 4 0 Kelch motif Kelch_4 PF13418.1 ETO32817.1 - 0.075 12.8 2.6 1.7 8.4 0.1 3.2 2 1 1 3 3 3 0 Galactose oxidase, central domain WD40 PF00400.27 ETO32818.1 - 7.5e-65 212.6 12.6 8.1e-13 47.7 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO32818.1 - 3.6e-10 38.5 3.0 0.011 13.9 0.0 4.2 1 1 3 4 4 4 4 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO32818.1 - 1.6e-09 37.7 0.5 6.1e-08 32.5 0.0 2.7 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 ETO32818.1 - 7.2e-08 31.5 8.6 0.25 10.0 0.7 4.9 1 1 4 5 5 5 4 Nup133 N terminal like PQQ_2 PF13360.1 ETO32818.1 - 5.5e-06 26.0 0.1 6.3e-05 22.5 0.0 2.1 1 1 1 2 2 2 2 PQQ-like domain Cytochrom_D1 PF02239.11 ETO32818.1 - 7e-06 24.5 0.3 0.004 15.5 0.0 2.5 1 1 0 2 2 2 2 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO32818.1 - 0.00022 20.4 1.4 0.1 11.6 0.1 3.1 1 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 ETO32818.1 - 0.0011 18.6 0.7 2.3 7.9 0.0 4.1 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 ETO32818.1 - 0.0029 16.8 4.5 1.1 8.6 0.1 4.0 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature DPPIV_N PF00930.16 ETO32818.1 - 0.023 13.2 0.0 3.6 6.0 0.0 2.9 1 1 2 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Hira PF07569.6 ETO32818.1 - 0.031 13.4 0.1 7.5 5.6 0.0 3.3 3 1 0 3 3 3 0 TUP1-like enhancer of split USP7_C2 PF14533.1 ETO32818.1 - 0.036 13.4 0.1 66 2.8 0.0 4.3 4 1 1 5 5 5 0 Ubiquitin-specific protease C-terminal Saw1 PF11561.3 ETO32820.1 - 0.26 10.6 7.7 0.11 11.8 2.5 1.9 2 0 0 2 2 2 0 Single strand annealing-weakened 1 Halogen_Hydrol PF10112.4 ETO32821.1 - 0.0047 16.3 0.3 0.0072 15.7 0.2 1.3 1 0 0 1 1 1 1 5-bromo-4-chloroindolyl phosphate hydrolysis protein WD40 PF00400.27 ETO32823.1 - 9e-12 44.3 0.1 3.3e-10 39.4 0.0 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO32823.1 - 2.6e-09 36.8 1.0 0.00093 19.2 0.1 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO32823.1 - 1.3e-06 27.8 0.8 0.015 14.8 0.1 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO32823.1 - 0.00018 21.4 0.9 0.97 9.4 0.2 3.7 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETO32823.1 - 0.00019 21.1 0.1 1.2 8.9 0.0 3.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO32823.1 - 0.0015 18.1 2.3 3.4 7.5 0.0 4.4 4 1 0 4 4 4 2 Kelch motif FAM74 PF15026.1 ETO32825.1 - 0.029 14.0 2.5 0.034 13.7 1.8 1.1 1 0 0 1 1 1 0 FAM74 protein Spexin PF15171.1 ETO32825.1 - 0.43 10.6 2.5 0.57 10.2 1.7 1.2 1 0 0 1 1 1 0 Neuropeptide secretory protein family, NPQ, spexin DUF4629 PF15442.1 ETO32825.1 - 3.6 7.7 10.6 4.8 7.3 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) Atg14 PF10186.4 ETO32825.1 - 4.7 6.0 8.7 5.8 5.7 6.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1764 PF08576.5 ETO32825.1 - 7.6 7.3 8.4 10 6.9 5.8 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) PCMT PF01135.14 ETO32826.1 - 5.5e-29 101.2 4.0 1.9e-20 73.2 0.0 3.1 2 1 0 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.8 ETO32827.1 - 0.057 12.7 0.5 0.63 9.3 0.0 2.2 2 0 0 2 2 2 0 Histone methylation protein DOT1 RRM_5 PF13893.1 ETO32827.1 - 0.093 12.6 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2 PF00096.21 ETO32828.1 - 0.00034 20.7 0.5 0.0016 18.6 0.3 2.2 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETO32828.1 - 0.012 15.9 0.3 0.012 15.9 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETO32828.1 - 0.091 13.0 0.2 0.091 13.0 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-Di19 PF05605.7 ETO32828.1 - 1.1 9.4 5.1 0.31 11.1 0.6 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DnaJ PF00226.26 ETO32829.1 - 1.2e-20 72.9 4.0 1.1e-13 50.6 0.3 2.5 2 0 0 2 2 2 2 DnaJ domain CTDII PF01556.13 ETO32829.1 - 4.3e-18 64.9 0.3 6.5e-09 35.5 0.1 3.4 3 0 0 3 3 3 3 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 ETO32829.1 - 5.3e-11 42.4 19.9 9.9e-11 41.5 13.8 1.5 1 0 0 1 1 1 1 DnaJ central domain 7TM_GPCR_Srh PF10318.4 ETO32829.1 - 0.0051 15.6 6.1 0.0081 15.0 4.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh XK-related PF09815.4 ETO32829.1 - 0.024 13.6 0.2 0.024 13.6 0.1 1.9 1 1 0 2 2 2 0 XK-related protein HypA PF01155.14 ETO32829.1 - 8.3 6.1 11.2 0.77 9.4 1.6 2.5 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Rhodanese PF00581.15 ETO32830.1 - 3.6e-16 59.5 1.7 5.5e-10 39.5 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain DUF2917 PF11142.3 ETO32830.1 - 0.071 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2917) DUF805 PF05656.9 ETO32831.1 - 0.39 10.5 0.0 0.39 10.5 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF805) PepSY_TM_2 PF13703.1 ETO32831.1 - 3.4 7.8 9.1 0.75 10.0 0.2 2.8 2 1 1 3 3 3 0 PepSY-associated TM helix AtpR PF12966.2 ETO32831.1 - 9.1 6.5 10.8 1.8 8.7 1.1 2.8 3 0 0 3 3 3 0 N-ATPase, AtpR subunit V_ATPase_I PF01496.14 ETO32834.1 - 2.8e-07 28.8 0.1 3.7e-07 28.4 0.1 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF2265 PF10023.4 ETO32834.1 - 0.053 12.6 0.0 0.058 12.5 0.0 1.0 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) ADH_zinc_N PF00107.21 ETO32835.1 - 1.1e-08 34.6 0.0 1.6e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETO32835.1 - 0.021 15.6 0.0 0.27 12.1 0.0 2.3 1 1 0 1 1 1 0 Zinc-binding dehydrogenase RGS PF00615.14 ETO32836.1 - 1.6e-08 34.6 2.4 1.6e-08 34.6 1.6 2.1 2 0 0 2 2 2 1 Regulator of G protein signaling domain NUDIX_4 PF14815.1 ETO32837.1 - 4.2 6.8 8.8 4.9 6.6 4.6 2.1 1 1 1 2 2 2 0 NUDIX domain Daxx PF03344.10 ETO32837.1 - 4.9 5.5 37.5 0.062 11.7 20.6 1.6 2 0 0 2 2 2 0 Daxx Family RhoGEF PF00621.15 ETO32838.1 - 6.9e-25 87.9 0.0 1.1e-24 87.2 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain DUF1732 PF08340.6 ETO32841.1 - 0.067 13.0 0.1 0.21 11.4 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1732) Mak10 PF04112.8 ETO32842.1 - 3.6e-05 23.0 0.6 0.0051 16.0 0.0 3.1 3 0 0 3 3 3 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase NB PF04159.8 ETO32842.1 - 0.11 12.2 0.5 0.31 10.8 0.3 1.7 1 0 0 1 1 1 0 NB glycoprotein DUF2201_N PF13203.1 ETO32842.1 - 0.17 10.9 4.4 0.35 9.9 3.1 1.5 1 0 0 1 1 1 0 Putative metallopeptidase domain YjgP_YjgQ PF03739.9 ETO32842.1 - 0.23 10.1 2.8 0.5 9.0 2.0 1.6 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF1510 PF07423.6 ETO32842.1 - 0.23 10.7 25.1 1 8.6 12.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) HA2 PF04408.18 ETO32842.1 - 0.93 9.5 7.2 7.3 6.6 0.0 3.1 3 0 0 3 3 3 0 Helicase associated domain (HA2) Kei1 PF08552.6 ETO32842.1 - 2.1 7.9 13.6 2.4 7.7 0.2 2.9 2 1 0 3 3 3 0 Inositolphosphorylceramide synthase subunit Kei1 Presenilin PF01080.12 ETO32842.1 - 4.4 6.0 5.8 9.4 4.9 1.9 2.3 2 0 0 2 2 2 0 Presenilin Melibiase PF02065.13 ETO32843.1 - 7.8e-07 28.1 0.1 6.9e-05 21.7 0.0 2.2 2 0 0 2 2 2 2 Melibiase Tubulin_C PF03953.12 ETO32844.1 - 7.2e-22 77.7 0.1 1.1e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 ETO32844.1 - 0.042 13.6 0.0 0.076 12.8 0.0 1.4 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain MRJP PF03022.11 ETO32845.1 - 6.3e-48 163.4 1.0 8.7e-48 162.9 0.7 1.1 1 0 0 1 1 1 1 Major royal jelly protein Reg_prop PF07494.6 ETO32845.1 - 3.2 8.0 5.6 2.5 8.3 0.0 3.1 3 0 0 3 3 3 0 Two component regulator propeller DUF605 PF04652.11 ETO32846.1 - 0.11 11.8 14.1 0.15 11.4 9.8 1.1 1 0 0 1 1 1 0 Vta1 like zf-C3HC4_2 PF13923.1 ETO32847.1 - 0.044 13.8 3.2 0.27 11.2 2.2 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Exotox-A_target PF09102.5 ETO32847.1 - 0.14 11.6 0.4 3.4 7.1 0.2 2.5 2 0 0 2 2 2 0 Exotoxin A, targeting TPR_11 PF13414.1 ETO32848.1 - 2.6e-05 23.7 5.8 0.77 9.4 0.2 4.8 3 1 1 4 4 4 2 TPR repeat TPR_2 PF07719.12 ETO32848.1 - 5.8e-05 22.6 4.0 1 9.4 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO32848.1 - 0.00043 20.1 0.3 4.5 7.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO32848.1 - 0.0016 19.0 0.0 22 5.8 0.0 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETO32848.1 - 0.009 15.7 3.8 23 5.0 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETO32848.1 - 0.03 13.9 5.9 9.6 6.0 0.3 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2411 PF10304.4 ETO32848.1 - 0.04 13.4 0.1 7.5 6.2 0.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF2411) L71 PF02448.10 ETO32848.1 - 0.043 13.6 0.1 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 L71 family TPR_17 PF13431.1 ETO32848.1 - 0.097 12.9 2.1 8.5 6.8 0.0 4.3 3 1 0 3 3 2 0 Tetratricopeptide repeat HCO3_cotransp PF00955.16 ETO32848.1 - 0.11 11.1 0.2 0.39 9.3 0.1 1.7 2 0 0 2 2 2 0 HCO3- transporter family TPR_19 PF14559.1 ETO32848.1 - 0.13 12.5 1.1 42 4.5 0.1 3.8 3 1 1 4 4 3 0 Tetratricopeptide repeat Ctr PF04145.10 ETO32848.1 - 0.18 11.8 2.5 3.4 7.6 1.1 2.9 3 1 0 3 3 3 0 Ctr copper transporter family Aminotran_3 PF00202.16 ETO32849.1 - 4.5e-36 124.3 0.0 5.2e-36 124.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III NUC130_3NT PF08158.7 ETO32849.1 - 0.002 18.3 0.5 0.22 11.8 0.1 3.3 2 1 1 3 3 3 1 NUC130/3NT domain Beta_elim_lyase PF01212.16 ETO32849.1 - 0.0027 16.9 0.0 0.0047 16.0 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 ETO32849.1 - 0.031 13.3 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 ETO32849.1 - 0.04 12.6 0.1 0.058 12.1 0.1 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Fe-S_biosyn PF01521.15 ETO32850.1 - 5e-12 45.7 1.7 5.6e-12 45.5 1.2 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis RGS PF00615.14 ETO32852.1 - 0.038 14.0 8.0 2.5 8.2 0.1 3.7 3 2 0 3 3 3 0 Regulator of G protein signaling domain FimP PF09766.4 ETO32853.1 - 2.7e-12 46.4 11.7 1.3e-11 44.1 0.4 2.3 1 1 1 2 2 2 2 Fms-interacting protein AIP3 PF03915.8 ETO32853.1 - 0.013 14.4 3.5 0.016 14.1 2.4 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 PcF PF09461.5 ETO32853.1 - 0.32 10.9 2.1 0.29 11.0 0.2 1.8 2 0 0 2 2 2 0 Phytotoxin PcF protein HrpE PF06188.7 ETO32853.1 - 0.39 10.4 3.6 0.7 9.6 2.5 1.5 1 1 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E MIP-T3 PF10243.4 ETO32854.1 - 2.7e-06 26.1 38.2 2.7e-06 26.1 26.5 1.8 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 DUF1777 PF08648.7 ETO32854.1 - 1.2 8.8 74.3 3.3e+02 0.8 51.5 3.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) C2 PF00168.25 ETO32856.1 - 0.0031 17.3 0.0 0.0092 15.8 0.0 1.8 1 0 0 1 1 1 1 C2 domain LMBR1 PF04791.11 ETO32856.1 - 1.1 7.8 4.3 2 6.8 3.0 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein CENP-B_dimeris PF09026.5 ETO32856.1 - 3.9 7.7 14.2 9.9 6.4 1.3 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain WD40 PF00400.27 ETO32858.1 - 1.1e-47 158.2 29.0 3.2e-10 39.4 0.2 6.9 6 2 1 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO32858.1 - 4.1e-06 25.2 7.9 0.0045 15.1 0.1 4.1 2 2 1 4 4 4 3 Nucleoporin Nup120/160 WD40 PF00400.27 ETO32859.1 - 5.5e-73 238.4 12.8 2.2e-13 49.5 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO32859.1 - 3.8e-10 38.6 2.5 3.6e-05 22.2 0.1 3.9 1 1 3 4 4 4 3 Cytochrome D1 heme domain Nup160 PF11715.3 ETO32859.1 - 7.4e-08 30.9 3.8 0.87 7.6 0.0 5.6 1 1 5 6 6 6 3 Nucleoporin Nup120/160 Kelch_5 PF13854.1 ETO32859.1 - 8.8e-08 31.9 6.3 0.0014 18.5 0.3 5.1 4 1 1 5 5 5 2 Kelch motif Nucleoporin_N PF08801.6 ETO32859.1 - 1.7e-06 27.1 6.4 1 7.9 0.0 5.1 2 1 3 5 5 5 3 Nup133 N terminal like Kelch_6 PF13964.1 ETO32859.1 - 3.4e-06 26.9 11.9 0.019 15.1 0.1 7.5 8 1 1 9 9 8 2 Kelch motif PD40 PF07676.7 ETO32859.1 - 3.9e-06 26.3 15.0 0.8 9.4 0.1 6.8 7 0 0 7 7 7 3 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO32859.1 - 0.00016 21.2 0.0 0.0018 17.8 0.0 2.7 1 1 0 1 1 1 1 PQQ-like domain DPPIV_N PF00930.16 ETO32859.1 - 0.00018 20.2 0.3 0.32 9.5 0.0 3.8 1 1 3 4 4 4 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nbas_N PF15492.1 ETO32859.1 - 0.00036 19.7 0.3 0.51 9.3 0.0 3.5 1 1 3 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Ricin_B_lectin PF00652.17 ETO32859.1 - 0.00046 20.2 1.3 0.27 11.2 0.1 3.1 2 1 1 3 3 3 1 Ricin-type beta-trefoil lectin domain Kelch_1 PF01344.20 ETO32859.1 - 0.002 17.6 10.3 0.0028 17.1 0.3 4.0 4 0 0 4 4 3 1 Kelch motif Kelch_3 PF13415.1 ETO32859.1 - 0.0022 18.1 1.9 0.086 13.0 0.1 3.9 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO32859.1 - 0.0035 17.0 4.2 4.5 7.2 0.0 5.1 5 0 0 5 5 5 2 Kelch motif MRJP PF03022.11 ETO32859.1 - 0.017 14.3 0.1 0.39 9.8 0.0 2.3 2 0 0 2 2 2 0 Major royal jelly protein Resistin PF06954.6 ETO32859.1 - 0.1 12.9 0.1 8 6.8 0.0 3.2 2 1 1 3 3 3 0 Resistin LCM PF04072.9 ETO32860.1 - 3.7e-05 23.3 0.0 0.00023 20.7 0.0 2.1 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Lep_receptor_Ig PF06328.6 ETO32860.1 - 0.024 14.4 0.1 0.064 13.1 0.1 1.7 1 0 0 1 1 1 0 Ig-like C2-type domain DAP PF15228.1 ETO32862.1 - 0.057 14.1 1.3 0.11 13.2 0.3 1.8 2 0 0 2 2 2 0 Death-associated protein Striatin PF08232.7 ETO32862.1 - 0.23 11.7 4.0 0.44 10.8 2.8 1.4 1 0 0 1 1 1 0 Striatin family DUF2731 PF10806.3 ETO32862.1 - 0.55 10.4 3.5 0.3 11.3 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2731) TB2_DP1_HVA22 PF03134.14 ETO32864.1 - 1.5e-09 37.4 2.3 2.2e-09 36.9 1.6 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family PABP PF00658.13 ETO32865.1 - 5.4e-08 32.3 0.2 9.2e-08 31.6 0.0 1.5 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain AAA PF00004.24 ETO32866.1 - 3.3e-35 121.1 0.0 4e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 ETO32866.1 - 1.2e-08 35.0 0.0 1.8e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 ETO32866.1 - 1.2e-06 28.6 0.1 0.023 14.8 0.0 2.1 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 ETO32866.1 - 1e-05 25.5 0.0 1.3e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 ETO32866.1 - 1.1e-05 26.2 0.1 2.9e-05 24.8 0.0 1.8 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.1 ETO32866.1 - 1.1e-05 25.7 0.0 1.7e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 ETO32866.1 - 2.5e-05 24.0 0.0 0.00039 20.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 ETO32866.1 - 0.00032 19.9 0.0 0.00044 19.4 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 ETO32866.1 - 0.00051 19.1 0.0 0.00086 18.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 ETO32866.1 - 0.00054 19.6 0.0 0.00088 18.9 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 ETO32866.1 - 0.00055 19.8 0.0 0.00081 19.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 ETO32866.1 - 0.0014 17.6 0.1 0.0032 16.5 0.1 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.8 ETO32866.1 - 0.0021 16.8 0.0 0.0027 16.4 0.0 1.1 1 0 0 1 1 1 1 TIP49 C-terminus ABC_tran PF00005.22 ETO32866.1 - 0.003 17.8 0.0 0.0038 17.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter RNA_helicase PF00910.17 ETO32866.1 - 0.0051 16.9 0.0 0.0096 16.0 0.0 1.5 1 1 0 1 1 1 1 RNA helicase AAA_3 PF07726.6 ETO32866.1 - 0.0055 16.3 0.0 0.0086 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 ETO32866.1 - 0.0061 16.4 0.1 0.011 15.5 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 ETO32866.1 - 0.024 14.1 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 ETO32866.1 - 0.031 13.7 0.0 0.059 12.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.7 ETO32866.1 - 0.034 13.8 0.0 0.26 10.9 0.0 2.0 1 1 1 2 2 2 0 NACHT domain DEAD PF00270.24 ETO32866.1 - 0.035 13.6 0.2 4.1 6.8 0.0 2.1 1 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_11 PF13086.1 ETO32866.1 - 0.05 13.1 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 ETO32866.1 - 0.066 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.1 ETO32866.1 - 0.091 12.7 0.0 0.18 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 ETO32866.1 - 0.092 11.8 0.0 0.41 9.7 0.0 1.8 2 0 0 2 2 2 0 KaiC Parvo_NS1 PF01057.12 ETO32866.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 ETO32866.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.1 ETO32866.1 - 0.15 11.4 0.7 4.6 6.5 0.1 2.0 1 1 0 2 2 2 0 AAA domain BRE1 PF08647.6 ETO32867.1 - 0.46 10.4 5.3 0.74 9.8 3.7 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF2457 PF10446.4 ETO32868.1 - 0.0069 15.1 11.6 0.0078 14.9 8.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) RXT2_N PF08595.6 ETO32868.1 - 0.033 14.0 10.1 0.066 13.0 7.0 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal IFT43 PF15305.1 ETO32868.1 - 0.036 14.0 10.8 0.05 13.6 7.5 1.2 1 0 0 1 1 1 0 Intraflagellar transport protein 43 ANAPC15 PF15243.1 ETO32868.1 - 0.044 13.8 13.6 0.09 12.8 9.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Pox_Ag35 PF03286.9 ETO32868.1 - 0.053 13.0 14.9 0.066 12.7 10.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nucleoplasmin PF03066.10 ETO32868.1 - 0.12 11.9 8.2 0.18 11.3 5.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin BTV_NS2 PF04514.7 ETO32868.1 - 0.33 9.8 14.1 0.35 9.7 9.8 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 PBP1_TM PF14812.1 ETO32868.1 - 0.82 10.0 21.2 1.9 8.8 14.7 1.8 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CobT PF06213.7 ETO32868.1 - 1.5 7.9 14.4 1.8 7.6 10.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CENP-B_dimeris PF09026.5 ETO32868.1 - 2.3 8.5 10.7 4 7.7 7.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF3987 PF13148.1 ETO32868.1 - 3.3 6.1 9.0 4 5.8 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) FAM176 PF14851.1 ETO32868.1 - 4.7 6.8 13.1 4.8 6.8 8.5 1.5 1 1 0 1 1 1 0 FAM176 family Hid1 PF12722.2 ETO32868.1 - 5.4 4.5 13.4 5.8 4.4 9.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.9 ETO32868.1 - 5.4 4.9 17.4 7 4.5 12.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Mit_KHE1 PF10173.4 ETO32868.1 - 6.4 6.5 7.5 11 5.7 5.1 1.5 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related ubiquitin PF00240.18 ETO32869.1 - 2.2e-09 36.5 0.4 7e-09 34.9 0.0 2.1 2 1 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 ETO32869.1 - 0.00015 21.3 0.0 0.00053 19.6 0.0 2.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Kelch_6 PF13964.1 ETO32870.1 - 3.1e-08 33.4 2.6 0.24 11.6 0.1 4.7 3 1 1 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO32870.1 - 0.00047 19.8 0.1 0.033 13.9 0.0 3.1 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO32870.1 - 0.00048 19.7 1.8 0.11 12.2 0.1 4.1 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 ETO32870.1 - 0.00063 19.2 5.6 0.0069 15.9 0.1 4.0 5 0 0 5 5 5 1 Kelch motif Kelch_5 PF13854.1 ETO32870.1 - 0.003 17.4 0.1 13 5.9 0.3 4.7 5 0 0 5 5 5 1 Kelch motif L27_2 PF09045.5 ETO32870.1 - 0.075 12.5 0.2 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 L27_2 Kelch_3 PF13415.1 ETO32870.1 - 0.13 12.4 0.0 3.1 8.0 0.0 3.2 4 0 0 4 4 4 0 Galactose oxidase, central domain HRDC PF00570.18 ETO32871.1 - 0.068 12.9 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 HRDC domain RRP7 PF12923.2 ETO32871.1 - 0.29 11.1 8.5 0.33 10.9 5.9 1.1 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) DUF3693 PF12472.3 ETO32871.1 - 0.81 9.3 2.6 1.4 8.5 0.5 2.4 2 1 0 2 2 2 0 Phage related protein RNase_H2-Ydr279 PF09468.5 ETO32871.1 - 6.8 5.7 8.1 7.7 5.6 5.6 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) WD40 PF00400.27 ETO32872.1 - 2.9e-32 109.3 8.3 1.5e-09 37.3 1.1 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO32872.1 - 4.3e-07 28.4 0.2 0.0017 16.5 0.1 3.0 3 0 0 3 3 3 3 Nucleoporin Nup120/160 WD40 PF00400.27 ETO32873.1 - 2.6e-41 138.0 3.4 1.4e-12 46.9 0.0 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat eIF2A PF08662.6 ETO32873.1 - 3e-10 40.1 0.1 1.4e-06 28.1 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 ETO32873.1 - 4.1e-06 25.8 0.6 0.023 13.4 0.1 2.1 1 1 1 2 2 2 2 Nup133 N terminal like PQQ_2 PF13360.1 ETO32873.1 - 0.00018 21.0 0.0 0.044 13.2 0.0 2.0 1 1 1 2 2 2 2 PQQ-like domain Nup160 PF11715.3 ETO32873.1 - 0.00025 19.3 0.0 0.21 9.7 0.0 2.2 1 1 0 2 2 2 2 Nucleoporin Nup120/160 PD40 PF07676.7 ETO32873.1 - 0.00045 19.7 0.2 0.27 10.9 0.0 3.8 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO32873.1 - 0.0017 16.7 0.9 0.0071 14.6 0.1 1.9 1 1 0 2 2 2 1 Cytochrome D1 heme domain Nop10p PF04135.7 ETO32873.1 - 0.0018 17.9 0.2 0.95 9.2 0.1 2.4 2 0 0 2 2 2 2 Nucleolar RNA-binding protein, Nop10p family Mid2 PF04478.7 ETO32873.1 - 0.0086 15.4 0.3 0.31 10.4 0.0 2.5 1 1 1 2 2 2 1 Mid2 like cell wall stress sensor Nbas_N PF15492.1 ETO32873.1 - 0.011 14.8 0.1 2.9 6.9 0.0 2.3 1 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal DPPIV_N PF00930.16 ETO32873.1 - 0.031 12.8 0.0 5.1 5.5 0.0 2.8 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9_N PF02897.10 ETO32873.1 - 0.041 12.4 0.4 0.12 10.8 0.3 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Smac_DIABLO PF09057.5 ETO32873.1 - 0.28 10.2 1.0 0.34 10.0 0.0 1.6 2 0 0 2 2 2 0 Second Mitochondria-derived Activator of Caspases OPA3 PF07047.7 ETO32874.1 - 1.4e-11 44.3 2.5 3.1e-11 43.1 0.0 2.4 1 1 0 2 2 2 1 Optic atrophy 3 protein (OPA3) UCR_UQCRX_QCR9 PF05365.7 ETO32875.1 - 5.7e-07 29.0 1.2 5.7e-07 29.0 0.8 1.7 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like NPFF PF15085.1 ETO32875.1 - 0.09 13.0 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Neuropeptide FF DUF1353 PF07087.6 ETO32876.1 - 0.08 12.4 0.2 1.1 8.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1353) DUF3452 PF11934.3 ETO32876.1 - 2 7.7 8.5 5.7 6.2 1.0 2.6 2 2 0 2 2 2 0 Domain of unknown function (DUF3452) Abhydrolase_6 PF12697.2 ETO32877.1 - 9.2e-10 38.7 0.0 1e-09 38.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETO32877.1 - 0.014 15.1 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2305 PF10230.4 ETO32877.1 - 0.078 12.3 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Zeta_toxin PF06414.7 ETO32878.1 - 0.0066 15.5 1.2 0.069 12.2 0.8 2.2 1 1 0 1 1 1 1 Zeta toxin DUF217 PF02697.9 ETO32878.1 - 0.15 12.3 0.3 0.15 12.3 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized ACR, COG1753 Caudo_TAP PF02413.12 ETO32878.1 - 1.1 9.4 5.1 0.4 10.8 0.5 2.2 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein RNA_pol_A_CTD PF03118.10 ETO32880.1 - 0.018 14.4 0.2 0.029 13.7 0.1 1.3 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain DUF3944 PF13099.1 ETO32880.1 - 0.031 13.7 0.5 0.058 12.8 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3944) HHH_5 PF14520.1 ETO32880.1 - 0.045 13.9 0.3 0.063 13.4 0.2 1.2 1 0 0 1 1 1 0 Helix-hairpin-helix domain AIG1 PF04548.11 ETO32881.1 - 7.5e-09 35.0 0.0 7.5e-09 35.0 0.0 2.6 3 0 0 3 3 3 1 AIG1 family Pox_A32 PF04665.7 ETO32881.1 - 5.4e-05 22.6 1.9 0.0001 21.6 0.1 2.2 2 0 0 2 2 2 1 Poxvirus A32 protein FtsK_SpoIIIE PF01580.13 ETO32881.1 - 0.00017 21.0 0.0 0.00044 19.7 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family T2SE PF00437.15 ETO32881.1 - 0.00029 19.8 0.0 0.00096 18.1 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein Miro PF08477.8 ETO32881.1 - 0.00029 21.3 0.9 0.0015 19.0 0.0 2.6 2 1 0 2 2 2 1 Miro-like protein MobB PF03205.9 ETO32881.1 - 0.00084 19.0 0.0 0.0027 17.4 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 ETO32881.1 - 0.0016 17.9 0.0 0.046 13.1 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 ETO32881.1 - 0.0017 18.0 0.0 0.0042 16.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain MMR_HSR1 PF01926.18 ETO32881.1 - 0.0021 17.9 2.8 0.0032 17.4 0.0 2.7 3 1 0 3 3 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 ETO32881.1 - 0.0036 16.7 1.8 0.036 13.4 0.0 2.4 2 1 0 2 2 2 1 AAA-like domain AAA_17 PF13207.1 ETO32881.1 - 0.0038 18.0 1.8 0.075 13.8 0.0 3.1 2 2 0 2 2 2 1 AAA domain SMC_N PF02463.14 ETO32881.1 - 0.0041 16.3 0.1 0.012 14.9 0.0 1.8 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 ETO32881.1 - 0.0041 17.2 0.1 0.025 14.7 0.0 2.3 3 0 0 3 3 3 1 AAA domain GTP_EFTU PF00009.22 ETO32881.1 - 0.0049 16.3 0.4 0.032 13.6 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain TrwB_AAD_bind PF10412.4 ETO32881.1 - 0.005 15.5 0.4 0.013 14.1 0.0 1.8 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain DUF3510 PF12022.3 ETO32881.1 - 0.0065 16.5 2.9 0.041 13.9 1.5 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) AAA_29 PF13555.1 ETO32881.1 - 0.0091 15.5 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 ETO32881.1 - 0.011 16.0 0.2 0.068 13.4 0.0 2.4 2 0 0 2 2 2 0 ABC transporter ATP_bind_1 PF03029.12 ETO32881.1 - 0.019 14.5 0.2 0.072 12.6 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 ETO32881.1 - 0.023 14.1 0.0 0.057 12.9 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 ETO32881.1 - 0.07 13.3 0.1 0.07 13.3 0.0 2.9 3 1 1 4 4 4 0 RNA helicase AAA_16 PF13191.1 ETO32881.1 - 0.093 12.7 0.1 0.42 10.5 0.0 2.1 3 0 0 3 3 3 0 AAA ATPase domain DUF87 PF01935.12 ETO32881.1 - 0.2 11.4 0.0 0.2 11.4 0.0 4.2 3 1 1 5 5 5 0 Domain of unknown function DUF87 AAA_18 PF13238.1 ETO32881.1 - 0.2 11.9 0.0 0.2 11.9 0.0 3.3 3 2 0 3 3 3 0 AAA domain Dynamin_N PF00350.18 ETO32881.1 - 0.33 10.7 0.0 0.33 10.7 0.0 4.3 4 1 1 5 5 5 0 Dynamin family ResIII PF04851.10 ETO32881.1 - 3.1 7.5 15.5 0.11 12.3 0.9 3.4 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit RabGAP-TBC PF00566.13 ETO32882.1 - 1.1e-43 149.1 3.6 1.1e-43 149.1 2.5 2.7 3 1 0 3 3 3 1 Rab-GTPase-TBC domain DUF349 PF03993.7 ETO32882.1 - 4 7.6 14.7 2 8.6 8.0 2.0 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) WD40 PF00400.27 ETO32883.1 - 1.7e-34 116.4 9.7 1.9e-12 46.5 0.1 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO32883.1 - 5.5e-07 28.0 0.1 0.14 10.2 0.0 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO32883.1 - 0.00065 18.5 2.8 0.0017 17.2 1.9 1.7 1 1 0 1 1 1 1 Nup133 N terminal like eIF2A PF08662.6 ETO32883.1 - 0.00085 19.0 0.0 0.041 13.5 0.0 2.3 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 ETO32883.1 - 0.01 14.9 0.1 3.7 6.5 0.0 2.8 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 ETO32883.1 - 0.042 12.1 0.0 0.15 10.3 0.0 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain Hira PF07569.6 ETO32883.1 - 0.065 12.4 0.0 16 4.6 0.0 2.8 2 1 1 3 3 3 0 TUP1-like enhancer of split PD40 PF07676.7 ETO32883.1 - 0.11 12.2 1.8 35 4.1 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 ETO32884.1 - 1.8e-76 249.5 15.1 2.7e-13 49.2 0.1 8.7 8 0 0 8 8 8 8 WD domain, G-beta repeat NACHT PF05729.7 ETO32884.1 - 2e-10 40.5 0.0 4e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Nup160 PF11715.3 ETO32884.1 - 3.5e-09 35.3 3.6 0.023 12.8 0.2 3.9 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO32884.1 - 3.5e-06 25.5 0.8 0.04 12.2 0.0 3.1 2 1 1 3 3 3 2 Cytochrome D1 heme domain Pentapeptide PF00805.17 ETO32884.1 - 2.1e-05 23.6 1.2 4.7e-05 22.5 0.8 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) AAA_18 PF13238.1 ETO32884.1 - 8.5e-05 22.8 0.1 0.0013 19.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETO32884.1 - 0.00045 20.3 0.0 0.0015 18.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain PD40 PF07676.7 ETO32884.1 - 0.00063 19.3 0.3 7.6 6.3 0.0 4.3 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat AAA_16 PF13191.1 ETO32884.1 - 0.01 15.8 0.2 0.045 13.7 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 ETO32884.1 - 0.014 16.2 0.0 0.079 13.7 0.0 2.4 1 0 0 1 1 1 0 AAA domain Proteasome_A_N PF10584.4 ETO32884.1 - 0.015 14.6 4.6 2.6 7.4 0.0 4.3 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature PQQ_2 PF13360.1 ETO32884.1 - 0.022 14.2 0.0 1.7 8.0 0.0 2.4 2 0 0 2 2 2 0 PQQ-like domain Pentapeptide_4 PF13599.1 ETO32884.1 - 0.026 14.3 0.0 0.082 12.7 0.0 1.8 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) UPF0118 PF01594.11 ETO32885.1 - 0.0049 15.9 0.1 0.0057 15.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF20 CUE PF02845.11 ETO32885.1 - 0.039 13.4 0.1 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 CUE domain HTH_34 PF13601.1 ETO32885.1 - 0.042 13.8 0.2 5.6 7.0 0.0 2.7 3 0 0 3 3 3 0 Winged helix DNA-binding domain TruB_N PF01509.13 ETO32885.1 - 0.082 13.0 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 TruB family pseudouridylate synthase (N terminal domain) WD40 PF00400.27 ETO32886.1 - 2.1e-63 208.0 23.0 1.5e-13 50.0 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO32886.1 - 3.4e-11 41.9 3.3 0.00041 18.6 0.0 4.4 1 1 2 4 4 4 4 Nucleoporin Nup120/160 HAD PF12710.2 ETO32886.1 - 0.06 13.5 1.1 1.1 9.3 0.8 2.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF851 PF05867.6 ETO32886.1 - 0.084 12.1 0.1 0.3 10.2 0.0 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF851) zf-TRAF PF02176.13 ETO32887.1 - 4.8e-05 23.6 7.7 4.8e-05 23.6 5.3 3.0 2 1 2 4 4 4 1 TRAF-type zinc finger HALZ PF02183.13 ETO32887.1 - 0.0036 16.9 3.8 0.0092 15.6 2.7 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper PTCB-BRCT PF12738.2 ETO32891.1 - 3.7e-39 132.4 19.6 5e-12 45.5 0.0 5.2 5 0 0 5 5 5 4 twin BRCT domain BRCT PF00533.21 ETO32891.1 - 3.1e-31 107.3 24.2 2.2e-11 43.7 0.1 7.7 8 1 0 8 8 8 4 BRCA1 C Terminus (BRCT) domain Vwaint PF14624.1 ETO32892.1 - 0.007 16.4 0.1 0.013 15.6 0.1 1.5 1 0 0 1 1 1 1 VWA / Hh protein intein-like LNS2 PF08235.8 ETO32892.1 - 0.023 14.2 1.4 1.2 8.6 0.2 2.0 1 1 1 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) WD40 PF00400.27 ETO32893.1 - 5.7e-09 35.5 1.2 3.6e-06 26.6 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO32893.1 - 0.016 13.3 0.0 0.02 13.0 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 EXS PF03124.9 ETO32893.1 - 0.03 13.3 0.1 0.038 12.9 0.1 1.3 1 0 0 1 1 1 0 EXS family DUF4458 PF14660.1 ETO32893.1 - 0.11 12.4 0.0 0.11 12.4 0.0 1.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4458) zf-TRAF PF02176.13 ETO32895.1 - 4.3e-05 23.8 0.2 4.3e-05 23.8 0.1 4.0 3 2 1 4 4 4 1 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 ETO32895.1 - 0.00023 21.1 8.2 0.00023 21.1 5.7 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 ETO32895.1 - 0.00073 19.3 7.2 0.00073 19.3 5.0 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Borrelia_orfD PF02999.9 ETO32895.1 - 0.0023 18.0 0.1 0.0041 17.2 0.1 1.5 1 0 0 1 1 1 1 Borrelia orf-D family zf-RING_UBOX PF13445.1 ETO32895.1 - 0.0037 16.9 5.9 0.0037 16.9 4.1 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.1 ETO32895.1 - 0.055 13.2 16.0 0.063 13.1 7.5 3.2 2 1 0 2 2 2 0 Ring finger domain zf-RING_6 PF14835.1 ETO32895.1 - 0.29 10.9 6.0 0.079 12.7 1.3 2.2 3 0 0 3 3 3 0 zf-RING of BARD1-type protein Kelch_2 PF07646.10 ETO32897.1 - 2.9e-05 23.6 0.7 0.064 13.0 0.1 3.1 2 1 1 3 3 3 2 Kelch motif Kelch_1 PF01344.20 ETO32897.1 - 0.00012 21.5 6.0 0.06 12.9 0.0 3.3 3 1 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETO32897.1 - 0.00013 21.6 0.1 0.0023 17.6 0.0 2.6 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO32897.1 - 0.00034 20.6 0.2 0.093 12.9 0.0 2.6 3 0 0 3 3 3 2 Kelch motif adh_short PF00106.20 ETO32898.1 - 0.0018 18.2 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase HlyC PF02794.11 ETO32898.1 - 0.078 12.5 0.3 0.72 9.4 0.0 2.3 2 0 0 2 2 2 0 RTX toxin acyltransferase family Pribosyltran PF00156.22 ETO32899.1 - 1.8e-20 72.9 0.0 2.5e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 ETO32899.1 - 0.00081 18.6 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 ETO32899.1 - 0.02 14.1 0.0 0.056 12.7 0.0 1.7 2 0 0 2 2 2 0 Phosphoribosyl transferase Ykof PF07615.6 ETO32899.1 - 0.029 14.5 0.1 2.3 8.4 0.0 2.4 2 0 0 2 2 2 0 YKOF-related Family Citrate_synt PF00285.16 ETO32900.1 - 5.2e-49 166.8 0.1 8.2e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 Citrate synthase Citrate_synt PF00285.16 ETO32901.1 - 2.2e-28 99.0 0.0 5.9e-17 61.4 0.0 2.1 2 0 0 2 2 2 2 Citrate synthase TPT PF03151.11 ETO32902.1 - 8e-13 48.3 14.1 2.3e-12 46.8 6.7 2.7 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 ETO32902.1 - 5.3e-06 25.5 17.3 2e-05 23.6 12.0 1.9 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 ETO32902.1 - 0.0001 22.3 14.9 0.00061 19.8 0.0 3.1 3 1 1 4 4 4 2 EamA-like transporter family UPF0546 PF10639.4 ETO32902.1 - 0.0072 16.1 2.8 0.011 15.5 0.3 2.4 2 1 1 3 3 3 1 Uncharacterised protein family UPF0546 Adap_comp_sub PF00928.16 ETO32903.1 - 3.3e-05 23.1 0.1 5.8e-05 22.3 0.0 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 ETO32903.1 - 0.024 14.3 0.1 2.4 7.8 0.0 2.3 2 0 0 2 2 2 0 Clathrin adaptor complex small chain RGS PF00615.14 ETO32904.1 - 1e-05 25.6 0.1 0.00013 22.0 0.1 2.2 1 1 0 1 1 1 1 Regulator of G protein signaling domain DUF3278 PF11683.3 ETO32905.1 - 0.0068 16.4 0.8 0.012 15.5 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3278) DUF912 PF06024.7 ETO32906.1 - 0.11 12.5 0.2 0.11 12.5 0.1 4.6 2 1 2 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Gemini_mov PF01708.11 ETO32906.1 - 0.17 11.4 2.2 2.2 7.8 0.0 2.9 3 0 0 3 3 3 0 Geminivirus putative movement protein DUF914 PF06027.7 ETO32906.1 - 5.1 5.8 9.0 4 6.1 3.0 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF914) LMBR1 PF04791.11 ETO32906.1 - 6.2 5.2 7.3 0.62 8.5 1.8 1.6 2 0 0 2 2 2 0 LMBR1-like membrane protein PI-PLC-X PF00388.14 ETO32907.1 - 0.002 17.5 0.0 0.019 14.3 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Yos1 PF08571.5 ETO32909.1 - 0.037 14.1 0.1 0.083 12.9 0.1 1.5 1 0 0 1 1 1 0 Yos1-like Ctr PF04145.10 ETO32910.1 - 0.0033 17.4 0.1 0.0033 17.4 0.1 3.5 3 2 0 3 3 3 1 Ctr copper transporter family Ribosomal_60s PF00428.14 ETO32910.1 - 0.057 13.8 7.4 0.25 11.7 5.1 2.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein Ion_trans PF00520.26 ETO32910.1 - 0.074 12.2 1.3 0.14 11.3 0.9 1.4 1 0 0 1 1 1 0 Ion transport protein ETRAMP PF09716.5 ETO32910.1 - 0.12 12.3 0.2 0.12 12.3 0.1 3.0 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) RIC3 PF15361.1 ETO32910.1 - 0.28 11.4 0.0 0.28 11.4 0.0 5.5 4 2 3 7 7 7 0 Resistance to inhibitors of cholinesterase homologue 3 MIP-T3 PF10243.4 ETO32910.1 - 5.9 5.2 44.8 0.0076 14.7 13.9 2.7 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 Methyltransf_32 PF13679.1 ETO32911.1 - 1.5e-05 24.6 2.0 1.5e-05 24.6 1.4 1.5 2 0 0 2 2 2 1 Methyltransferase domain Tho2 PF11262.3 ETO32911.1 - 0.076 12.0 0.5 0.091 11.7 0.3 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Methyltransf_31 PF13847.1 ETO32912.1 - 0.0097 15.5 0.1 0.017 14.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETO32912.1 - 0.026 13.9 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.1 ETO32912.1 - 0.035 13.7 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain YihI PF04220.7 ETO32912.1 - 0.04 13.2 1.7 0.052 12.8 1.2 1.2 1 0 0 1 1 1 0 Der GTPase activator (YihI) DUF4213 PF13938.1 ETO32912.1 - 0.14 12.3 0.0 2.2 8.4 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4213) DAO PF01266.19 ETO32913.1 - 5.7e-16 58.3 0.0 1.1e-15 57.3 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 ETO32913.1 - 0.036 14.1 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETO32913.1 - 0.092 11.1 0.0 0.14 10.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Ribosomal_L2 PF00181.18 ETO32913.1 - 0.13 12.2 0.1 13 5.7 0.0 2.4 2 0 0 2 2 2 0 Ribosomal Proteins L2, RNA binding domain IF4E PF01652.13 ETO32915.1 - 7e-43 146.0 1.0 9.1e-43 145.6 0.7 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Trefoil PF00088.13 ETO32916.1 - 3.1e-12 45.9 7.7 5.8e-12 45.0 5.3 1.5 1 0 0 1 1 1 1 Trefoil (P-type) domain Glyco_hydro_15 PF00723.16 ETO32916.1 - 1.7e-06 26.8 0.0 2.3e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 RGS PF00615.14 ETO32917.1 - 3.8e-10 39.9 0.6 7.6e-10 38.9 0.4 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain STAT_int PF02865.12 ETO32917.1 - 0.051 13.5 0.7 0.094 12.6 0.1 1.8 2 0 0 2 2 2 0 STAT protein, protein interaction domain CPSase_L_D2 PF02786.12 ETO32917.1 - 0.12 11.5 0.1 0.22 10.7 0.1 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Rhabdo_matrix PF03397.9 ETO32918.1 - 0.011 15.0 0.0 0.034 13.4 0.0 1.7 1 1 0 1 1 1 0 Rhabdovirus matrix protein DUF4110 PF13422.1 ETO32918.1 - 0.028 14.2 0.2 0.096 12.5 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) VWA PF00092.23 ETO32919.1 - 5.9e-11 42.4 0.5 9.4e-11 41.7 0.3 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 ETO32919.1 - 0.0048 17.0 0.1 0.012 15.6 0.1 1.6 1 1 1 2 2 2 1 von Willebrand factor type A domain RhaT PF06379.7 ETO32919.1 - 0.037 12.9 0.3 0.057 12.3 0.2 1.3 1 0 0 1 1 1 0 L-rhamnose-proton symport protein (RhaT) Serinc PF03348.10 ETO32920.1 - 0.022 13.4 2.2 0.045 12.4 1.5 1.5 1 0 0 1 1 1 0 Serine incorporator (Serinc) ShK PF01549.19 ETO32920.1 - 0.041 14.2 9.3 0.095 13.0 6.4 1.7 1 0 0 1 1 1 0 ShK domain-like DUF373 PF04123.8 ETO32921.1 - 0.15 11.0 1.4 0.21 10.5 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF1068 PF06364.7 ETO32921.1 - 0.25 10.9 2.0 0.52 9.8 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) Synaptobrevin PF00957.16 ETO32921.1 - 0.72 9.5 0.0 0.72 9.5 0.0 3.0 3 0 0 3 3 3 0 Synaptobrevin Sigma_reg_N PF13800.1 ETO32921.1 - 1.2 9.2 10.6 2.3 8.3 4.0 3.0 3 0 0 3 3 3 0 Sigma factor regulator N-terminal RRM_1 PF00076.17 ETO32922.1 - 1.2e-19 69.7 0.0 2.7e-19 68.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO32922.1 - 5.2e-14 51.9 0.0 1.3e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO32922.1 - 6.4e-11 41.9 0.0 1.5e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETO32922.1 - 0.00034 20.3 0.0 0.00087 19.0 0.0 1.7 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 ETO32922.1 - 0.067 13.0 0.3 0.55 10.1 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif zf-C3HC4_2 PF13923.1 ETO32923.1 - 0.38 10.8 3.8 1.3 9.1 2.6 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C2HC5 PF06221.8 ETO32923.1 - 1 9.1 5.5 2.9 7.7 0.1 2.7 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-C3HC4 PF00097.20 ETO32923.1 - 1.7 8.3 6.6 0.52 10.0 1.9 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO32923.1 - 2.6 7.7 9.5 2.3 7.9 1.7 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SPX PF03105.14 ETO32924.1 - 0.00099 18.9 37.2 0.00099 18.9 25.8 3.9 1 1 2 3 3 3 1 SPX domain Innexin PF00876.13 ETO32925.1 - 0.0092 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Innexin EB1_binding PF05937.6 ETO32925.1 - 0.03 14.7 0.4 0.048 14.0 0.2 1.6 1 1 0 1 1 1 0 EB-1 Binding Domain EGF PF00008.22 ETO32927.1 - 0.18 11.8 0.8 0.18 11.8 0.6 2.1 2 0 0 2 2 2 0 EGF-like domain PHD PF00628.24 ETO32928.1 - 7.1e-12 44.8 21.1 1.8e-08 33.9 3.2 2.9 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.17 ETO32928.1 - 0.00024 20.7 4.6 0.00024 20.7 3.2 3.6 3 1 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H_2 PF13832.1 ETO32928.1 - 0.062 13.3 21.7 0.087 12.8 6.7 2.9 1 1 0 2 2 2 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 ETO32928.1 - 0.22 11.7 19.5 0.069 13.3 5.0 2.8 1 1 0 2 2 2 0 PHD-like zinc-binding domain zf-MIZ PF02891.15 ETO32928.1 - 0.92 9.0 15.9 1.5 8.4 0.7 3.1 2 1 0 2 2 2 0 MIZ/SP-RING zinc finger zf-TRM13_CCCH PF11722.3 ETO32928.1 - 1.1 8.6 6.0 0.28 10.5 1.2 2.3 2 0 0 2 2 2 0 CCCH zinc finger in TRM13 protein FANCL_C PF11793.3 ETO32928.1 - 1.7 8.6 29.2 0.47 10.4 4.6 4.5 3 1 2 5 5 5 0 FANCL C-terminal domain WD40 PF00400.27 ETO32929.1 - 8.8e-70 228.3 47.5 1.2e-12 47.1 0.1 8.7 7 2 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO32929.1 - 3.7e-13 48.4 16.2 0.015 13.4 0.1 6.1 2 1 3 5 5 5 5 Nucleoporin Nup120/160 IncA PF04156.9 ETO32929.1 - 0.0025 17.4 4.1 0.0042 16.6 2.9 1.3 1 0 0 1 1 1 1 IncA protein FLO_LFY PF01698.11 ETO32930.1 - 1.6 7.4 7.3 1.9 7.2 5.1 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF572 PF04502.8 ETO32930.1 - 2.9 7.0 19.3 4.2 6.4 13.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Herpes_UL4 PF03277.8 ETO32932.1 - 0.0049 16.1 0.0 0.006 15.8 0.0 1.1 1 0 0 1 1 1 1 Herpesvirus UL4 family Nefa_Nip30_N PF10187.4 ETO32932.1 - 0.045 13.9 1.9 0.093 12.9 1.3 1.5 1 0 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF2762 PF10960.3 ETO32932.1 - 0.13 11.9 1.9 0.3 10.8 1.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2762) p450 PF00067.17 ETO32933.1 - 7.4e-14 51.1 0.0 9.8e-14 50.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4227 PF14004.1 ETO32935.1 - 0.014 15.2 0.3 0.021 14.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) DUF2393 PF09624.5 ETO32935.1 - 0.083 12.4 0.1 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) DUF912 PF06024.7 ETO32936.1 - 5.5 7.1 0.0 5.5 7.1 0.0 4.2 3 1 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2802 PF10975.3 ETO32936.1 - 6 6.6 8.8 13 5.6 6.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) 3HCDH PF00725.17 ETO32937.1 - 8e-18 64.6 0.0 2.3e-17 63.1 0.0 1.7 1 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 3HCDH_N PF02737.13 ETO32938.1 - 1.1e-22 80.5 0.0 1.4e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 ETO32938.1 - 3e-05 23.4 0.0 3.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ldh_1_N PF00056.18 ETO32938.1 - 0.00028 20.7 0.0 0.00042 20.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 ETO32938.1 - 0.00043 19.4 0.0 0.00063 18.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 ETO32938.1 - 0.0035 17.2 0.0 0.0045 16.8 0.0 1.4 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 ETO32938.1 - 0.004 16.8 0.0 0.0076 15.9 0.0 1.5 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 ETO32938.1 - 0.0043 16.5 0.1 0.012 15.0 0.0 1.7 1 1 1 2 2 2 1 Ketopantoate reductase PanE/ApbA L27_2 PF09045.5 ETO32938.1 - 0.015 14.8 0.1 0.043 13.3 0.0 1.8 1 0 0 1 1 1 0 L27_2 AlaDh_PNT_C PF01262.16 ETO32938.1 - 0.029 13.9 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UPF0146 PF03686.8 ETO32938.1 - 0.031 14.1 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) PUL PF08324.6 ETO32939.1 - 2.6e-05 23.1 4.3 0.021 13.6 0.1 2.3 2 0 0 2 2 2 2 PUL domain ABC_membrane PF00664.18 ETO32939.1 - 0.0043 16.5 0.6 0.0075 15.7 0.4 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF1510 PF07423.6 ETO32940.1 - 0.0029 16.9 8.6 0.0029 16.9 5.9 5.4 6 1 0 6 6 6 3 Protein of unknown function (DUF1510) DUF2681 PF10883.3 ETO32940.1 - 0.0062 16.7 10.2 0.0062 16.7 7.0 5.4 5 0 0 5 5 5 1 Protein of unknown function (DUF2681) SAM_1 PF00536.25 ETO32940.1 - 0.0063 16.6 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) FHIPEP PF00771.15 ETO32940.1 - 2.4 6.3 11.8 0.99 7.6 1.9 2.5 2 0 0 2 2 2 0 FHIPEP family Sec6 PF06046.8 ETO32941.1 - 1.2e-40 139.1 20.2 1.5e-40 138.8 14.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec6 DUF445 PF04286.7 ETO32941.1 - 0.0017 17.9 5.5 0.32 10.4 0.1 2.3 1 1 0 2 2 2 2 Protein of unknown function (DUF445) V-SNARE_C PF12352.3 ETO32941.1 - 0.11 12.5 0.2 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus Armet PF10208.4 ETO32942.1 - 0.016 14.8 0.8 0.16 11.6 0.2 2.3 2 0 0 2 2 2 0 Degradation arginine-rich protein for mis-folding MTTB PF06253.6 ETO32942.1 - 0.06 11.0 0.1 0.087 10.5 0.1 1.2 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) PDGF_N PF04692.8 ETO32942.1 - 0.13 12.8 1.1 0.33 11.4 0.0 2.3 3 0 0 3 3 3 0 Platelet-derived growth factor, N terminal region Secretin_N_2 PF07655.8 ETO32942.1 - 0.32 11.4 16.5 0.91 9.9 11.5 1.8 1 0 0 1 1 1 0 Secretin N-terminal domain RasGEF_N PF00618.15 ETO32944.1 - 0.0012 18.9 0.1 0.0031 17.5 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif WD40 PF00400.27 ETO32946.1 - 1e-62 205.9 28.9 3.8e-11 42.4 1.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO32946.1 - 8.2e-13 47.3 5.0 0.018 13.1 0.1 5.6 2 1 4 6 6 6 5 Nucleoporin Nup120/160 Mito_fiss_reg PF05308.6 ETO32946.1 - 0.2 10.9 3.4 0.29 10.4 2.4 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Fer4_4 PF12800.2 ETO32947.1 - 8.7 6.9 10.5 0.49 10.8 1.1 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain TPR_12 PF13424.1 ETO32948.1 - 1.9e-25 88.6 5.6 1.5e-16 60.0 1.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO32948.1 - 8.7e-16 56.7 10.4 2.9e-09 36.1 0.8 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO32948.1 - 4e-15 55.1 0.0 1.9e-09 37.1 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO32948.1 - 1.6e-14 52.4 1.0 0.00013 21.5 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO32948.1 - 4.1e-13 48.7 9.9 4.7e-11 42.1 2.5 2.3 1 1 1 2 2 2 2 TPR repeat TPR_8 PF13181.1 ETO32948.1 - 2.8e-12 45.4 6.1 9.1e-05 21.9 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO32948.1 - 9.6e-10 37.6 7.9 7.9e-05 22.2 0.4 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat SNAP PF14938.1 ETO32948.1 - 1.9e-08 33.7 1.1 2.3e-08 33.5 0.8 1.2 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP MIT PF04212.13 ETO32948.1 - 6.3e-06 25.9 4.3 0.059 13.2 0.1 3.2 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain DUF2225 PF09986.4 ETO32948.1 - 2.6e-05 23.7 4.0 4.8e-05 22.9 2.6 1.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_14 PF13428.1 ETO32948.1 - 5.9e-05 23.3 0.0 4.9 8.0 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO32948.1 - 0.00022 21.1 3.7 1.5 9.2 0.0 3.5 2 2 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO32948.1 - 0.001 19.1 8.0 0.015 15.3 5.7 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETO32948.1 - 0.0053 17.1 0.8 5.4 7.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO32948.1 - 0.0059 17.2 0.0 0.24 12.1 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO32948.1 - 0.017 14.3 0.0 0.51 9.6 0.0 2.3 2 0 0 2 2 2 0 SHNi-TPR MotB_plug PF13677.1 ETO32948.1 - 0.033 13.5 0.8 0.22 10.8 0.1 2.2 2 0 0 2 2 2 0 Membrane MotB of proton-channel complex MotA/MotB RPN7 PF10602.4 ETO32948.1 - 0.05 12.9 2.5 6 6.2 0.2 2.4 1 1 0 2 2 2 0 26S proteasome subunit RPN7 DUF3366 PF11846.3 ETO32948.1 - 0.056 13.3 0.0 0.074 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) Foie-gras_1 PF11817.3 ETO32948.1 - 0.07 12.5 0.2 0.098 12.1 0.1 1.3 1 0 0 1 1 1 0 Foie gras liver health family 1 Sec5 PF15469.1 ETO32948.1 - 0.12 12.1 1.5 0.73 9.5 0.3 2.2 2 1 0 2 2 2 0 Exocyst complex component Sec5 NSF PF02071.15 ETO32948.1 - 0.56 10.9 13.9 2.6 8.9 0.2 4.2 3 1 1 4 4 4 0 Aromatic-di-Alanine (AdAR) repeat TPR_12 PF13424.1 ETO32949.1 - 5.6e-19 67.8 0.1 1.4e-15 56.9 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO32949.1 - 2.5e-15 55.8 6.9 4.2e-09 35.9 0.5 2.6 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 ETO32949.1 - 8.7e-14 50.4 9.2 5.4e-08 32.1 2.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO32949.1 - 4.2e-12 45.5 0.0 1.5e-07 31.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO32949.1 - 9.1e-12 43.9 4.2 3.6e-06 26.4 0.8 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO32949.1 - 3e-08 32.8 9.7 0.00024 20.6 1.7 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO32949.1 - 7.6e-08 31.5 0.0 7.4e-06 25.3 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO32949.1 - 1.6e-05 24.7 0.1 0.071 13.3 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat BRCA-2_OB3 PF09104.5 ETO32949.1 - 0.00018 21.3 0.3 0.00037 20.3 0.2 1.5 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 MIT PF04212.13 ETO32949.1 - 0.0009 19.0 0.4 0.01 15.6 0.2 2.5 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain SNAP PF14938.1 ETO32949.1 - 0.0013 17.9 0.4 0.0023 17.1 0.3 1.3 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.1 ETO32949.1 - 0.022 15.1 0.7 0.28 11.7 0.1 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETO32949.1 - 0.04 14.6 0.0 0.15 12.8 0.0 1.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETO32949.1 - 0.052 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Apc3 PF12895.2 ETO32949.1 - 0.06 13.4 2.7 0.14 12.3 1.1 2.2 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 PSP94 PF05825.6 ETO32949.1 - 0.099 12.9 0.3 0.099 12.9 0.2 2.2 3 0 0 3 3 2 0 Beta-microseminoprotein (PSP-94) TPR_3 PF07720.7 ETO32949.1 - 0.11 12.2 0.4 0.11 12.2 0.3 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat LAM_C PF12544.3 ETO32949.1 - 1.2 9.1 5.5 1.1 9.3 0.7 2.4 2 0 0 2 2 2 0 Lysine-2,3-aminomutase WD40 PF00400.27 ETO32950.1 - 7.2e-74 241.2 23.8 8e-12 44.5 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO32950.1 - 2.2e-09 36.0 9.4 0.33 9.0 0.0 6.0 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Str_synth PF03088.11 ETO32950.1 - 9.9e-06 25.5 0.1 8.6 6.4 0.0 4.3 3 1 1 4 4 4 1 Strictosidine synthase Nbas_N PF15492.1 ETO32950.1 - 2.4e-05 23.5 4.5 0.041 12.9 0.2 4.4 2 1 3 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Resistin PF06954.6 ETO32950.1 - 0.00049 20.3 0.6 38 4.6 0.0 4.7 3 1 2 5 5 5 0 Resistin Nucleoporin_N PF08801.6 ETO32950.1 - 0.00054 18.8 14.9 0.99 8.0 0.1 5.0 2 1 3 5 5 5 3 Nup133 N terminal like PD40 PF07676.7 ETO32950.1 - 0.0023 17.5 13.1 5.9 6.6 0.0 5.5 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO32950.1 - 0.029 12.6 2.8 0.57 8.4 0.2 2.9 2 1 2 4 4 4 0 Cytochrome D1 heme domain DUF1258 PF06869.7 ETO32950.1 - 0.033 13.2 0.3 7 5.6 0.0 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF1258) SGL PF08450.7 ETO32950.1 - 0.073 12.4 0.1 3.7 6.8 0.0 3.0 1 1 1 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region Peptidase_C69 PF03577.10 ETO32950.1 - 0.08 11.7 0.6 5.1 5.8 0.0 2.7 3 0 0 3 3 3 0 Peptidase family C69 DUF1652 PF07865.6 ETO32950.1 - 0.099 12.2 0.5 51 3.5 0.0 4.1 6 0 0 6 6 6 0 Protein of unknown function (DUF1652) SusE PF14292.1 ETO32950.1 - 0.12 12.2 0.0 27 4.6 0.0 3.5 3 1 1 4 4 4 0 SusE outer membrane protein Gmad1 PF10647.4 ETO32950.1 - 0.16 11.3 0.1 9.6 5.5 0.0 3.3 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain Dicty_REP PF05086.7 ETO32951.1 - 0.03 12.0 10.5 0.034 11.9 7.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pex14_N PF04695.8 ETO32951.1 - 0.057 13.4 11.4 0.081 12.9 7.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF999 PF06198.6 ETO32951.1 - 0.059 13.1 0.9 0.074 12.8 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF999) Nop53 PF07767.6 ETO32951.1 - 0.082 11.8 10.3 0.099 11.6 7.2 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF3535 PF12054.3 ETO32951.1 - 0.095 11.3 6.3 0.12 10.9 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) BNIP2 PF12496.3 ETO32951.1 - 0.12 12.5 3.6 0.18 11.9 2.5 1.3 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Senescence_reg PF04520.8 ETO32951.1 - 0.53 10.7 4.1 0.69 10.4 2.9 1.2 1 0 0 1 1 1 0 Senescence regulator OmpH PF03938.9 ETO32951.1 - 0.83 9.5 17.4 1 9.2 12.0 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.1 ETO32951.1 - 9.9 5.0 9.6 13 4.6 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sulfotransfer_3 PF13469.1 ETO32953.1 - 9.9e-05 23.3 0.0 0.00037 21.4 0.0 2.1 1 1 0 1 1 1 1 Sulfotransferase family PAP_assoc PF03828.14 ETO32955.1 - 2.6e-16 59.3 0.3 1e-15 57.4 0.1 2.1 2 0 0 2 2 2 1 Cid1 family poly A polymerase Eapp_C PF10238.4 ETO32955.1 - 0.012 15.5 2.9 0.023 14.5 2.0 1.6 1 0 0 1 1 1 0 E2F-associated phosphoprotein tRNA_NucTransf2 PF09249.6 ETO32955.1 - 0.029 14.2 0.0 2.9 7.7 0.0 2.7 3 0 0 3 3 3 0 tRNA nucleotidyltransferase, second domain Apis_Csd PF11671.3 ETO32955.1 - 3.5 7.4 10.9 11 5.7 3.8 3.3 3 1 1 4 4 4 0 Complementary sex determiner protein CZB PF13682.1 ETO32956.1 - 0.65 10.2 4.2 0.72 10.0 0.3 2.6 2 0 0 2 2 2 0 Chemoreceptor zinc-binding domain DEAD PF00270.24 ETO32957.1 - 1e-38 132.4 0.0 1.7e-38 131.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase CMS1 PF14617.1 ETO32957.1 - 6.3e-05 22.1 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.10 ETO32957.1 - 0.00011 22.0 0.0 0.00037 20.3 0.0 1.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 ETO32957.1 - 0.007 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 SecA DEAD-like domain AAA_22 PF13401.1 ETO32957.1 - 0.075 13.1 0.4 17 5.5 0.1 2.7 2 1 0 2 2 2 0 AAA domain DUF1003 PF06210.6 ETO32958.1 - 0.07 13.0 1.7 0.15 12.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) UPF0118 PF01594.11 ETO32959.1 - 0.07 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF20 bZIP_1 PF00170.16 ETO32959.1 - 0.14 12.1 1.3 0.33 10.9 0.9 1.7 1 0 0 1 1 1 0 bZIP transcription factor ZZ PF00569.12 ETO32960.1 - 3.3e-14 52.1 8.2 3.3e-14 52.1 5.7 3.0 3 0 0 3 3 3 2 Zinc finger, ZZ type Hormone_4 PF00220.12 ETO32961.1 - 0.051 13.2 0.4 0.1 12.2 0.3 1.5 1 0 0 1 1 1 0 Neurohypophysial hormones, N-terminal Domain Dynein_heavy PF03028.10 ETO32961.1 - 0.32 8.9 10.3 0.42 8.5 7.2 1.3 1 0 0 1 1 1 0 Dynein heavy chain and region D6 of dynein motor ATP-synt_ab PF00006.20 ETO32962.1 - 3.2e-44 150.9 0.0 4.2e-44 150.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 ETO32962.1 - 9.1e-16 58.3 0.1 1.4e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 ETO32963.1 - 1.1e-14 54.3 0.2 2e-14 53.5 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab PF00006.20 ETO32963.1 - 2e-06 27.4 0.0 2.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain HAS-barrel PF09378.5 ETO32963.1 - 0.014 15.2 0.1 0.024 14.5 0.1 1.4 1 0 0 1 1 1 0 HAS barrel domain DUF2258 PF10015.4 ETO32964.1 - 0.077 12.8 0.1 0.21 11.4 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2258) Pro_dh PF01619.13 ETO32966.1 - 0.055 12.4 0.1 0.065 12.2 0.1 1.1 1 0 0 1 1 1 0 Proline dehydrogenase Ycf1 PF05758.7 ETO32968.1 - 0.12 10.1 3.9 0.13 9.9 2.7 1.1 1 0 0 1 1 1 0 Ycf1 AFT PF08731.6 ETO32968.1 - 1.4 9.1 7.4 2.4 8.3 4.0 2.0 2 0 0 2 2 2 0 Transcription factor AFT DDHD PF02862.12 ETO32968.1 - 1.8 8.3 6.9 16 5.1 4.1 2.1 2 0 0 2 2 2 0 DDHD domain Sec62 PF03839.11 ETO32968.1 - 5.6 6.2 13.6 36 3.6 0.0 2.3 2 0 0 2 2 2 0 Translocation protein Sec62 Vfa1 PF08432.5 ETO32968.1 - 8.4 6.3 17.4 15 5.5 12.1 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Kelch_1 PF01344.20 ETO32969.1 - 3e-08 33.0 0.4 0.00032 20.1 0.4 2.7 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.1 ETO32969.1 - 1.3e-06 28.2 0.6 0.0032 17.5 0.1 2.9 1 1 1 2 2 2 2 Kelch motif Kelch_2 PF07646.10 ETO32969.1 - 6.3e-06 25.7 0.2 0.014 15.1 0.1 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETO32969.1 - 6.7e-05 22.5 0.0 0.13 12.0 0.0 2.6 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO32969.1 - 0.00023 21.0 0.4 0.14 12.1 0.2 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 ETO32969.1 - 0.047 13.8 0.0 16 5.8 0.0 2.6 2 0 0 2 2 2 0 Galactose oxidase, central domain WD40 PF00400.27 ETO32970.1 - 5.1e-51 168.8 9.0 2.4e-13 49.4 0.1 4.0 4 0 0 4 4 4 4 WD domain, G-beta repeat eIF2A PF08662.6 ETO32970.1 - 6.8e-08 32.4 0.4 5.4e-06 26.2 0.1 2.0 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO32970.1 - 6.7e-07 27.8 0.5 0.086 10.9 0.0 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO32970.1 - 0.00014 20.7 2.9 0.8 8.3 0.4 3.5 1 1 2 3 3 3 2 Nup133 N terminal like PD40 PF07676.7 ETO32970.1 - 0.00035 20.1 2.5 6.2 6.6 0.0 4.0 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO32970.1 - 0.0025 17.3 0.1 0.17 11.3 0.0 2.1 1 1 1 2 2 2 2 PQQ-like domain DUF4221 PF13970.1 ETO32970.1 - 0.0027 17.0 0.2 0.69 9.1 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4221) Nbas_N PF15492.1 ETO32970.1 - 0.01 14.9 0.1 0.051 12.6 0.0 1.9 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Resistin PF06954.6 ETO32970.1 - 0.018 15.3 0.2 2.7 8.3 0.1 2.7 1 1 1 2 2 2 0 Resistin DUF1258 PF06869.7 ETO32970.1 - 0.034 13.2 0.6 0.62 9.1 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1258) Cytochrom_D1 PF02239.11 ETO32970.1 - 0.036 12.3 0.0 0.83 7.8 0.0 2.1 1 1 1 2 2 2 0 Cytochrome D1 heme domain B_lectin PF01453.19 ETO32970.1 - 0.042 13.7 0.2 0.19 11.5 0.1 1.9 1 1 1 2 2 2 0 D-mannose binding lectin Mid2 PF04478.7 ETO32970.1 - 0.059 12.7 0.7 1.7 8.0 0.1 2.6 1 1 1 3 3 3 0 Mid2 like cell wall stress sensor TFIIIC_delta PF12657.2 ETO32970.1 - 0.086 12.5 0.4 0.42 10.2 0.3 1.9 1 1 0 1 1 1 0 Transcription factor IIIC subunit delta N-term Proteasome_A_N PF10584.4 ETO32970.1 - 0.13 11.6 1.3 22 4.5 0.1 3.1 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 ETO32971.1 - 1.5e-10 40.5 1.0 3.7e-10 39.2 0.5 1.9 2 0 0 2 2 2 1 WD domain, G-beta repeat HAD PF12710.2 ETO32971.1 - 0.088 12.9 0.0 0.11 12.6 0.0 1.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ank_2 PF12796.2 ETO32972.1 - 0.00046 20.4 0.0 1.1 9.6 0.0 3.1 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO32972.1 - 0.069 13.6 0.1 3.7 8.1 0.0 3.1 3 1 1 4 4 4 0 Ankyrin repeats (many copies) WD40 PF00400.27 ETO32974.1 - 2.6e-64 210.9 25.5 1.2e-12 47.1 0.1 7.0 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO32974.1 - 1.5e-09 36.5 5.6 0.014 13.5 0.3 5.6 2 1 2 4 4 4 4 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO32974.1 - 4.5e-05 23.7 1.9 4.5e-05 23.7 1.3 2.6 2 1 1 3 3 3 1 TRAF-type zinc finger BBS2_Mid PF14783.1 ETO32974.1 - 0.0018 18.0 0.0 2 8.2 0.0 4.3 2 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region HAD PF12710.2 ETO32974.1 - 0.021 15.0 0.1 8.3 6.5 0.1 3.4 3 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase Spc7 PF08317.6 ETO32974.1 - 0.034 12.8 23.7 0.056 12.0 16.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.10 ETO32974.1 - 0.52 9.4 9.8 0.8 8.8 6.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit WD40 PF00400.27 ETO32975.1 - 8.8e-84 272.6 16.5 2.3e-13 49.4 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO32975.1 - 9.4e-15 54.8 4.2 4.8e-06 26.4 0.2 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO32975.1 - 3.6e-08 32.0 5.4 0.012 13.8 0.1 4.6 1 1 2 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO32975.1 - 2.1e-07 30.6 1.1 8.6e-05 22.1 0.2 3.6 1 1 3 4 4 4 2 PQQ-like domain Cytochrom_D1 PF02239.11 ETO32975.1 - 2.4e-06 26.0 1.1 0.0031 15.8 0.1 3.0 1 1 3 4 4 4 3 Cytochrome D1 heme domain DUF4221 PF13970.1 ETO32975.1 - 7.3e-05 22.2 2.8 0.13 11.5 0.1 3.4 1 1 0 3 3 3 2 Domain of unknown function (DUF4221) RicinB_lectin_2 PF14200.1 ETO32975.1 - 0.00088 19.6 2.7 0.17 12.2 0.1 3.2 1 1 1 3 3 3 1 Ricin-type beta-trefoil lectin domain-like Nbas_N PF15492.1 ETO32975.1 - 0.0021 17.2 0.3 1.4 7.9 0.0 3.5 1 1 3 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Resistin PF06954.6 ETO32975.1 - 0.0025 18.0 1.5 26 5.1 0.1 4.2 1 1 4 5 5 5 0 Resistin Gmad1 PF10647.4 ETO32975.1 - 0.0043 16.5 0.1 0.14 11.5 0.0 2.3 1 1 1 2 2 2 1 Lipoprotein LpqB beta-propeller domain PD40 PF07676.7 ETO32975.1 - 0.0076 15.9 11.0 5.3 6.8 0.0 6.2 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat USP7_C2 PF14533.1 ETO32975.1 - 0.028 13.8 1.9 1.8 7.9 0.2 3.6 2 2 1 3 3 3 0 Ubiquitin-specific protease C-terminal DUF3732 PF12532.3 ETO32975.1 - 0.051 13.0 0.4 16 4.9 0.0 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF3732) Proteasome_A_N PF10584.4 ETO32975.1 - 0.061 12.6 0.9 39 3.7 0.0 4.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature RST PF12174.3 ETO32976.1 - 0.29 10.9 0.0 0.29 10.9 0.0 3.0 3 0 0 3 3 3 0 RCD1-SRO-TAF4 (RST) plant domain DUF3023 PF11224.3 ETO32977.1 - 0.023 14.3 1.5 0.036 13.7 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3023) DUF2675 PF11247.3 ETO32977.1 - 0.061 13.3 0.2 1.9 8.6 0.0 2.4 1 1 1 3 3 3 0 Protein of unknown function (DUF2675) Na_Ca_ex PF01699.19 ETO32978.1 - 5.9e-14 51.8 5.9 7.3e-14 51.5 4.1 1.1 1 0 0 1 1 1 1 Sodium/calcium exchanger protein Lipase_bact_N PF12262.3 ETO32978.1 - 0.011 14.9 0.0 0.013 14.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial virulence factor lipase N-terminal Iron_permease PF04120.7 ETO32978.1 - 0.14 11.6 4.6 0.27 10.8 3.2 1.4 1 0 0 1 1 1 0 Low affinity iron permease RNase_PH_C PF03725.10 ETO32979.1 - 4.1e-09 36.2 0.0 7.4e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF2838 PF10998.3 ETO32980.1 - 3.9e-27 94.3 8.1 3.9e-27 94.3 5.6 3.0 3 1 0 3 3 3 1 Protein of unknown function (DUF2838) EST1 PF10374.4 ETO32980.1 - 0.31 11.0 3.1 0.6 10.1 2.2 1.4 1 0 0 1 1 1 0 Telomerase activating protein Est1 Kelch_6 PF13964.1 ETO32981.1 - 1.1e-09 37.9 0.7 0.0023 18.0 0.0 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO32981.1 - 1.8e-06 27.5 0.8 0.0047 16.6 0.0 4.2 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO32981.1 - 4.4e-06 26.1 2.3 0.0029 17.0 0.0 4.4 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 ETO32981.1 - 1.2e-05 25.1 0.9 1.4 8.9 0.0 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 ETO32981.1 - 2.5e-05 24.3 0.2 0.06 13.5 0.0 4.7 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO32981.1 - 4.5e-05 23.0 1.6 0.37 10.6 0.0 4.8 6 0 0 6 6 6 2 Kelch motif EF-hand_6 PF13405.1 ETO32982.1 - 3.5e-07 29.5 3.7 0.049 13.5 0.0 4.1 3 1 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 ETO32982.1 - 1.6e-05 24.9 1.5 0.0015 18.6 0.0 2.5 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO32982.1 - 2.4e-05 23.2 2.2 1.2 8.6 0.0 3.8 4 0 0 4 4 4 2 EF hand SPC25 PF06703.6 ETO32982.1 - 0.027 14.0 0.1 0.036 13.6 0.1 1.3 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) EF-hand_8 PF13833.1 ETO32982.1 - 0.028 14.0 1.2 2.3 7.8 0.1 2.7 2 1 1 3 3 3 0 EF-hand domain pair DUF3887 PF13026.1 ETO32982.1 - 1.4 9.2 5.1 1.1 9.5 0.1 2.4 2 1 0 3 3 3 0 Protein of unknown function (DUF3887) Peptidase_C14 PF00656.17 ETO32983.1 - 9.1e-10 38.6 0.3 3.9e-09 36.5 0.2 2.1 1 0 0 1 1 1 1 Caspase domain Kelch_5 PF13854.1 ETO32983.1 - 5.5e-08 32.6 0.4 0.009 15.9 0.1 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO32983.1 - 2.1e-05 23.9 14.4 0.00022 20.7 0.1 5.0 6 0 0 6 6 6 2 Kelch motif Kelch_6 PF13964.1 ETO32983.1 - 7.7e-05 22.7 5.2 1.2 9.4 0.0 5.7 5 1 1 6 6 6 2 Kelch motif Kelch_3 PF13415.1 ETO32983.1 - 0.017 15.3 0.0 1.5 9.0 0.0 3.7 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO32983.1 - 0.1 12.4 5.5 3 7.7 0.0 4.1 5 0 0 5 5 5 0 Kelch motif WD40 PF00400.27 ETO32984.1 - 7.3e-09 35.1 12.7 4.3e-07 29.5 0.0 5.0 6 0 0 6 6 6 3 WD domain, G-beta repeat Methuselah_N PF06652.7 ETO32985.1 - 0.016 14.7 0.8 0.026 14.1 0.6 1.4 1 0 0 1 1 1 0 Methuselah N-terminus Clathrin PF00637.15 ETO32986.1 - 2.7e-13 49.7 6.6 9.4e-13 47.9 0.6 3.1 2 1 1 3 3 3 1 Region in Clathrin and VPS TPR_19 PF14559.1 ETO32986.1 - 0.028 14.7 0.1 0.44 10.9 0.0 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR_2 PF13041.1 ETO32986.1 - 0.063 13.2 0.1 17 5.5 0.0 3.8 4 0 0 4 4 4 0 PPR repeat family DUF2796 PF10986.3 ETO32986.1 - 0.11 12.4 14.1 0.35 10.8 9.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) MA3 PF02847.12 ETO32986.1 - 0.31 10.7 0.0 0.31 10.7 0.0 3.4 5 0 0 5 5 5 0 MA3 domain Glyco_hydro_30 PF02055.11 ETO32987.1 - 1.9e-35 122.0 0.1 2.4e-35 121.6 0.1 1.0 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 BRCT PF00533.21 ETO32988.1 - 0.00028 20.9 0.1 0.00049 20.1 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Pol_alpha_B_N PF08418.5 ETO32988.1 - 0.0014 18.2 0.4 0.0018 17.8 0.2 1.2 1 1 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal CDC73 PF05179.9 ETO32988.1 - 0.013 14.8 0.2 0.021 14.2 0.1 1.3 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family Cofilin_ADF PF00241.15 ETO32989.1 - 9.6e-06 25.5 0.7 0.00017 21.4 0.5 2.5 1 1 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein LRR_4 PF12799.2 ETO32990.1 - 1.1e-13 50.4 9.3 2.6e-07 30.1 0.5 2.9 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 ETO32990.1 - 4.5e-06 26.3 2.2 2.9e-05 23.7 1.5 2.0 1 1 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.28 ETO32990.1 - 0.00012 21.6 1.4 0.9 9.8 0.1 4.3 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_8 PF13855.1 ETO32990.1 - 0.00015 21.4 6.0 0.0054 16.4 2.2 3.6 2 1 2 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 ETO32990.1 - 0.00039 20.2 0.6 0.58 10.4 0.0 3.6 3 0 0 3 3 3 1 Leucine Rich repeat LRR_7 PF13504.1 ETO32990.1 - 0.0069 16.4 3.4 2.2 8.8 0.2 4.1 4 0 0 4 4 4 1 Leucine rich repeat Ribosomal_L18ae PF01775.12 ETO32991.1 - 2.6e-45 153.2 0.3 4.4e-45 152.5 0.2 1.4 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Thioredoxin PF00085.15 ETO32993.1 - 2e-25 88.4 5.1 7.7e-13 48.0 0.1 2.7 2 1 0 3 3 3 2 Thioredoxin Thioredoxin_7 PF13899.1 ETO32993.1 - 8.1e-11 41.7 0.5 0.00059 19.7 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 ETO32993.1 - 5.8e-08 32.9 3.0 0.0017 18.5 0.2 2.9 1 1 1 2 2 2 2 Thioredoxin-like domain AhpC-TSA PF00578.16 ETO32993.1 - 5.8e-05 22.7 0.9 0.004 16.8 0.1 2.4 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_8 PF13905.1 ETO32993.1 - 0.00088 19.3 6.7 0.11 12.6 0.2 3.1 2 2 1 3 3 3 2 Thioredoxin-like RPA_C PF08784.6 ETO32993.1 - 0.028 14.8 0.2 0.05 14.0 0.2 1.5 1 0 0 1 1 1 0 Replication protein A C terminal Redoxin PF08534.5 ETO32993.1 - 0.048 13.1 0.5 0.64 9.5 0.1 2.7 2 1 1 3 3 3 0 Redoxin DDE_Tnp_1_2 PF13586.1 ETO32993.1 - 0.056 13.6 0.0 1.4 9.1 0.0 2.7 2 0 0 2 2 2 0 Transposase DDE domain His_kinase PF06580.8 ETO32994.1 - 0.12 12.3 3.0 2.6 8.0 0.1 2.5 2 0 0 2 2 2 0 Histidine kinase XisI PF08869.6 ETO32994.1 - 0.12 12.4 3.8 0.68 10.0 0.2 2.7 3 0 0 3 3 3 0 XisI protein DUF3505 PF12013.3 ETO32996.1 - 0.028 14.6 0.2 0.041 14.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) zf-RING_UBOX PF13445.1 ETO32996.1 - 0.037 13.7 0.0 0.083 12.6 0.0 1.6 1 0 0 1 1 1 0 RING-type zinc-finger NVEALA PF14055.1 ETO32996.1 - 0.062 13.0 0.4 0.13 11.9 0.3 1.5 1 0 0 1 1 1 0 NVEALA protein G-alpha PF00503.15 ETO32997.1 - 1e-37 129.7 0.5 1.1e-37 129.6 0.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO32997.1 - 0.058 12.6 0.0 0.091 11.9 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO32997.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF1162 PF06650.7 ETO32999.1 - 7.4e-10 38.4 0.1 1.1e-09 37.9 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1162) Dynein_heavy PF03028.10 ETO33001.1 - 2.9e-202 673.5 0.0 1.3e-201 671.3 0.0 1.8 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor AAA_9 PF12781.2 ETO33001.1 - 7e-46 155.9 3.8 1.9e-32 111.9 0.6 2.5 2 0 0 2 2 2 2 ATP-binding dynein motor region D5 AAA_8 PF12780.2 ETO33002.1 - 1.3e-68 230.9 0.4 7.2e-67 225.1 0.3 2.3 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 ETO33002.1 - 1.5e-52 178.3 0.0 2.5e-52 177.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 MT PF12777.2 ETO33002.1 - 2.8e-51 174.2 8.2 4.8e-51 173.5 5.7 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 ETO33002.1 - 1.5e-11 44.2 0.0 2.7e-09 36.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 ETO33002.1 - 0.0044 16.5 0.1 0.016 14.7 0.0 2.0 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_16 PF13191.1 ETO33002.1 - 0.0048 16.8 0.7 1.4 8.8 0.0 4.1 4 0 0 4 4 4 1 AAA ATPase domain RmuC PF02646.11 ETO33002.1 - 0.0068 15.2 8.7 0.08 11.7 2.1 2.5 2 0 0 2 2 2 2 RmuC family T2SE PF00437.15 ETO33002.1 - 0.013 14.4 0.0 0.059 12.2 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.1 ETO33002.1 - 0.013 15.6 0.0 0.066 13.3 0.0 2.3 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 ETO33002.1 - 0.027 13.9 0.4 0.15 11.5 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.24 ETO33002.1 - 0.031 14.4 0.0 1.3 9.2 0.0 3.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Reo_sigmaC PF04582.7 ETO33002.1 - 0.039 13.1 2.3 5.9 5.9 0.5 2.5 2 0 0 2 2 2 0 Reovirus sigma C capsid protein CCDC144C PF14915.1 ETO33002.1 - 0.05 12.5 17.2 0.34 9.7 5.3 2.4 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region COG2 PF06148.6 ETO33002.1 - 0.34 10.7 14.7 0.17 11.7 1.3 3.4 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Cast PF10174.4 ETO33002.1 - 0.35 8.8 24.5 0.97 7.3 17.0 1.6 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone IncA PF04156.9 ETO33002.1 - 0.6 9.6 16.5 0.33 10.5 0.3 3.0 2 1 0 2 2 2 0 IncA protein Atg14 PF10186.4 ETO33002.1 - 0.68 8.8 13.4 2.7 6.8 0.3 2.3 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 COesterase PF00135.23 ETO33003.1 - 8.5e-60 202.9 5.1 1.6e-29 103.0 0.7 2.4 2 1 0 2 2 2 2 Carboxylesterase family DUF1479 PF07350.7 ETO33004.1 - 1.1e-08 34.0 1.2 2e-05 23.2 0.1 2.7 1 1 0 2 2 2 2 Protein of unknown function (DUF1479) PhyH PF05721.8 ETO33004.1 - 4.6e-08 33.3 0.0 9.3e-08 32.3 0.0 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Suf PF05843.9 ETO33004.1 - 0.0014 18.4 2.1 0.0022 17.7 1.4 1.3 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) IncA PF04156.9 ETO33004.1 - 0.081 12.5 12.3 0.14 11.7 8.6 1.3 1 0 0 1 1 1 0 IncA protein DUF3952 PF13130.1 ETO33004.1 - 6.5 6.7 7.9 18 5.3 5.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3952) Pro_isomerase PF00160.16 ETO33005.1 - 7.1e-17 62.0 0.0 1.1e-16 61.4 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD G-alpha PF00503.15 ETO33006.1 - 4.5e-12 45.3 0.1 5e-12 45.2 0.1 1.1 1 0 0 1 1 1 1 G-protein alpha subunit DUF258 PF03193.11 ETO33006.1 - 8.9e-05 21.7 0.0 9.6e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 ETO33006.1 - 0.00041 20.6 0.1 0.00054 20.2 0.0 1.4 1 1 0 1 1 1 1 ABC transporter RNA_helicase PF00910.17 ETO33006.1 - 0.00047 20.3 0.0 0.00066 19.8 0.0 1.3 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.1 ETO33006.1 - 0.0017 18.4 0.1 0.0023 17.9 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.1 ETO33006.1 - 0.0018 18.2 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 ETO33006.1 - 0.0018 17.0 0.0 0.002 16.9 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein PduV-EutP PF10662.4 ETO33006.1 - 0.0033 16.9 0.2 0.0084 15.6 0.1 1.7 1 1 1 2 2 2 1 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 ETO33006.1 - 0.0054 15.6 0.0 0.0059 15.5 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.1 ETO33006.1 - 0.0069 16.2 0.0 0.0095 15.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 ETO33006.1 - 0.007 16.5 0.0 0.0089 16.2 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 ETO33006.1 - 0.0097 15.6 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase Sigma54_activ_2 PF14532.1 ETO33006.1 - 0.014 15.4 0.0 0.018 15.1 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.1 ETO33006.1 - 0.015 14.7 0.1 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.8 ETO33006.1 - 0.023 13.6 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_23 PF13476.1 ETO33006.1 - 0.023 15.0 0.0 0.025 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 ETO33006.1 - 0.026 14.6 0.0 0.032 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 ETO33006.1 - 0.028 14.3 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 ETO33006.1 - 0.033 13.8 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.16 ETO33006.1 - 0.035 13.2 0.0 0.054 12.6 0.0 1.4 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 ETO33006.1 - 0.038 14.3 0.0 0.053 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 ETO33006.1 - 0.039 13.1 0.1 0.046 12.9 0.1 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PRK PF00485.13 ETO33006.1 - 0.046 13.2 0.0 0.063 12.8 0.0 1.3 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.7 ETO33006.1 - 0.054 12.5 0.0 0.089 11.8 0.0 1.3 1 1 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 ETO33006.1 - 0.057 14.2 0.0 0.069 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 ETO33006.1 - 0.064 12.1 0.0 0.065 12.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_PrkA PF08298.6 ETO33006.1 - 0.07 11.8 0.0 0.099 11.3 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain AAA_5 PF07728.9 ETO33006.1 - 0.081 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DAP3 PF10236.4 ETO33006.1 - 0.12 11.2 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 IstB_IS21 PF01695.12 ETO33006.1 - 0.14 11.5 0.1 1 8.7 0.1 2.0 1 1 0 1 1 1 0 IstB-like ATP binding protein WD40 PF00400.27 ETO33007.1 - 9.1e-60 196.5 24.8 5.5e-11 41.9 0.1 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO33007.1 - 1.1e-12 46.8 1.2 0.052 11.6 0.0 5.3 2 2 1 4 4 4 4 Nucleoporin Nup120/160 WD40 PF00400.27 ETO33008.1 - 1.2e-64 212.0 32.7 2.2e-12 46.3 0.9 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO33008.1 - 1.5e-11 43.1 7.4 0.00033 18.9 0.1 5.9 4 2 2 6 6 6 6 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO33008.1 - 0.0066 16.2 3.1 12 5.7 0.0 4.5 3 2 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Marek_SORF3 PF07153.6 ETO33008.1 - 0.07 11.7 3.0 8.6 4.9 0.4 3.2 2 2 1 3 3 3 0 Marek's disease-like virus SORF3 protein Cupin_1 PF00190.17 ETO33008.1 - 0.43 10.0 3.6 3.1 7.2 0.4 3.0 2 1 0 2 2 2 0 Cupin WD40 PF00400.27 ETO33009.1 - 1.6e-13 49.9 7.7 3.2e-05 23.6 0.1 3.6 3 1 0 3 3 3 3 WD domain, G-beta repeat WD40 PF00400.27 ETO33010.1 - 4.1e-33 112.0 17.7 1.4e-11 43.8 0.4 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO33010.1 - 1.7e-06 26.4 1.7 0.038 12.1 0.0 3.2 1 1 2 3 3 3 3 Nucleoporin Nup120/160 WD40 PF00400.27 ETO33011.1 - 6.2e-23 79.7 2.5 4.1e-10 39.1 0.1 3.6 3 1 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO33011.1 - 0.013 13.6 0.1 0.093 10.8 0.0 1.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Staphylcoagulse PF04022.7 ETO33011.1 - 0.16 11.3 0.4 0.16 11.3 0.3 2.2 2 0 0 2 2 2 0 Staphylocoagulase repeat Ank_2 PF12796.2 ETO33012.1 - 0.0008 19.7 1.9 0.0031 17.8 0.0 2.6 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO33012.1 - 0.0017 18.8 1.8 0.024 15.1 0.0 3.3 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO33012.1 - 0.0064 16.7 1.5 0.24 11.7 0.0 3.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 ETO33012.1 - 0.051 13.4 0.1 0.57 10.0 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeat FRG PF08867.6 ETO33012.1 - 0.062 13.8 6.6 0.22 12.0 0.4 2.3 2 0 0 2 2 2 0 FRG domain BTB PF00651.26 ETO33013.1 - 2.2e-15 56.5 0.1 3.6e-15 55.9 0.1 1.3 1 1 0 1 1 1 1 BTB/POZ domain DRIM PF07539.7 ETO33013.1 - 0.00057 19.3 0.0 0.00078 18.8 0.0 1.2 1 0 0 1 1 1 1 Down-regulated in metastasis VWD PF00094.20 ETO33014.1 - 1.6e-07 31.6 0.8 4.5e-07 30.1 0.6 1.8 1 0 0 1 1 1 1 von Willebrand factor type D domain EGF PF00008.22 ETO33014.1 - 0.0003 20.6 5.6 0.0003 20.6 3.9 3.1 5 0 0 5 5 5 1 EGF-like domain DUF3586 PF12131.3 ETO33015.1 - 0.043 13.8 0.2 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3586) DWNN PF08783.6 ETO33015.1 - 0.75 9.7 0.1 0.75 9.7 0.1 2.5 2 0 0 2 2 2 0 DWNN domain Chromo_shadow PF01393.14 ETO33016.1 - 0.035 13.9 0.1 2.1 8.2 0.0 2.2 2 0 0 2 2 2 0 Chromo shadow domain DUF1179 PF06678.6 ETO33017.1 - 1.1 9.6 4.2 1.4 9.2 2.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1179) Zip PF02535.17 ETO33019.1 - 0.17 10.8 0.2 0.25 10.3 0.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter ALMS_motif PF15309.1 ETO33019.1 - 7.7 6.3 11.4 0.44 10.3 0.4 2.3 2 0 0 2 2 2 0 ALMS motif DEP PF00610.16 ETO33020.1 - 1e-14 54.0 0.3 1.7e-14 53.2 0.2 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Apc4 PF12896.2 ETO33021.1 - 0.012 14.9 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 Mad3_BUB1_II PF08171.6 ETO33021.1 - 0.11 12.4 1.0 1.8 8.5 0.0 2.6 3 0 0 3 3 3 0 Mad3/BUB1 homology region 2 dDENN PF03455.14 ETO33022.1 - 0.035 14.1 0.5 0.13 12.3 0.1 2.0 2 0 0 2 2 2 0 dDENN domain VD10_N PF08476.5 ETO33022.1 - 0.039 13.4 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 Viral D10 N-terminal CDC45 PF02724.9 ETO33023.1 - 0.012 13.6 6.0 0.012 13.7 4.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Toxin_18 PF08087.6 ETO33023.1 - 0.1 12.3 0.1 0.26 11.0 0.1 1.6 1 0 0 1 1 1 0 Conotoxin O-superfamily DUF3439 PF11921.3 ETO33023.1 - 0.75 9.5 6.6 3.6 7.3 4.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Ctr PF04145.10 ETO33023.1 - 1.1 9.3 0.0 1.1 9.3 0.0 2.5 1 1 1 2 2 2 0 Ctr copper transporter family DUF2413 PF10310.4 ETO33023.1 - 5.3 5.7 23.0 8.7 5.0 16.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) U-box PF04564.10 ETO33024.1 - 1.5e-18 66.5 2.3 9.9e-18 63.8 0.0 3.1 2 0 0 2 2 2 1 U-box domain zf-Nse PF11789.3 ETO33024.1 - 0.0082 15.6 1.8 0.012 15.0 0.2 2.1 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit RXT2_N PF08595.6 ETO33024.1 - 0.011 15.5 9.4 0.011 15.5 6.5 5.2 2 2 2 4 4 4 0 RXT2-like, N-terminal OAD_gamma PF04277.8 ETO33024.1 - 3.3 8.1 0.0 3.3 8.1 0.0 3.8 3 1 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain TPR_12 PF13424.1 ETO33025.1 - 1.2e-64 214.2 16.4 1.1e-18 66.8 0.1 4.6 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETO33025.1 - 1.5e-31 107.3 0.0 4.9e-08 32.6 0.1 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETO33025.1 - 1.1e-30 105.0 32.9 1.1e-11 44.1 0.1 5.4 2 2 3 5 5 5 5 TPR repeat TPR_1 PF00515.23 ETO33025.1 - 1.4e-30 103.6 32.3 3.7e-06 26.3 0.8 7.4 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.1 ETO33025.1 - 1.5e-27 93.1 5.9 7.7e-05 22.2 0.1 7.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETO33025.1 - 1.6e-24 83.7 25.6 6.4e-05 22.5 0.1 6.9 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETO33025.1 - 4.7e-19 66.6 30.5 0.00034 20.1 0.6 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.1 ETO33025.1 - 1.3e-08 34.7 5.6 0.032 14.7 0.0 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO33025.1 - 1.5e-07 31.8 1.1 0.19 12.4 0.1 4.7 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETO33025.1 - 8.2e-07 28.7 12.9 0.18 12.0 0.2 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO33025.1 - 4.5e-06 26.8 0.1 5.9 7.8 0.2 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO33025.1 - 6.3e-06 26.2 12.3 0.0078 16.3 0.2 4.4 2 2 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 ETO33025.1 - 2.8e-05 23.2 0.2 0.017 14.3 0.0 4.2 4 0 0 4 4 4 1 SHNi-TPR TPR_3 PF07720.7 ETO33025.1 - 0.0053 16.5 17.4 0.3 10.9 0.1 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO33025.1 - 0.084 13.2 2.0 11 6.4 0.0 3.8 5 0 0 5 5 4 0 Tetratricopeptide repeat NFRKB_winged PF14465.1 ETO33026.1 - 0.0049 16.6 0.0 0.0082 15.9 0.0 1.4 1 0 0 1 1 1 1 NFRKB Winged Helix-like Ric8 PF10165.4 ETO33027.1 - 0.03 13.1 0.6 0.053 12.3 0.4 1.3 1 0 0 1 1 1 0 Guanine nucleotide exchange factor synembryn RRN9 PF10680.4 ETO33029.1 - 0.012 15.2 0.1 3.8 7.3 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor DUF4361 PF14274.1 ETO33029.1 - 0.17 11.5 3.0 0.26 10.9 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4361) ADH_zinc_N PF00107.21 ETO33031.1 - 7e-14 51.4 0.1 3.4e-13 49.2 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETO33031.1 - 8.7e-14 52.5 0.0 3.2e-13 50.6 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Peptidase_S28 PF05577.7 ETO33032.1 - 4.9e-18 64.9 0.7 6.3e-18 64.5 0.5 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S28 PF05577.7 ETO33033.1 - 2.2e-23 82.5 0.3 4.4e-23 81.5 0.2 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.6 ETO33033.1 - 0.17 10.2 2.2 1.5 7.1 0.0 2.1 2 0 0 2 2 2 0 PS-10 peptidase S37 RIC3 PF15361.1 ETO33035.1 - 0.036 14.3 8.2 1.4 9.1 3.2 2.4 2 1 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 FHIPEP PF00771.15 ETO33035.1 - 0.041 12.2 0.2 0.044 12.1 0.1 1.1 1 0 0 1 1 1 0 FHIPEP family Afi1 PF07792.7 ETO33035.1 - 0.15 12.1 12.0 0.86 9.6 0.1 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF3464 PF11947.3 ETO33035.1 - 0.49 9.8 7.3 0.1 12.0 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) DUF788 PF05620.6 ETO33035.1 - 0.54 10.0 9.6 0.56 10.0 5.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF788) Ctr PF04145.10 ETO33035.1 - 1.8 8.5 7.1 0.36 10.8 2.2 1.7 1 1 1 2 2 2 0 Ctr copper transporter family PDR_CDR PF06422.7 ETO33035.1 - 2.1 8.0 5.0 0.55 9.9 1.1 1.7 2 0 0 2 2 2 0 CDR ABC transporter DUF1179 PF06678.6 ETO33035.1 - 2.4 8.4 10.5 0.31 11.3 4.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) AIF_C PF14721.1 ETO33035.1 - 4.5 7.5 9.0 6.7 6.9 3.5 2.0 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term OATP PF03137.15 ETO33035.1 - 5.1 5.0 9.9 0.85 7.5 4.0 1.6 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF2217 PF10265.4 ETO33035.1 - 6.2 5.4 11.5 0.15 10.7 3.6 1.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) TMEM223 PF14640.1 ETO33035.1 - 6.4 6.6 8.3 4 7.3 1.6 2.2 1 1 1 2 2 2 0 Transmembrane protein 223 Pkinase PF00069.20 ETO33037.1 - 8.2e-72 241.4 1.4 1.1e-69 234.5 1.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO33037.1 - 6.2e-37 127.0 0.3 2.5e-33 115.2 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.18 ETO33037.1 - 0.0011 18.8 0.1 0.0029 17.3 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 ETO33037.1 - 0.012 14.6 0.1 0.023 13.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 ETO33037.1 - 0.022 14.0 0.1 0.13 11.6 0.0 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Mcp5_PH PF12814.2 ETO33038.1 - 0.062 13.2 0.1 0.085 12.7 0.1 1.3 1 1 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology SNARE PF05739.14 ETO33039.1 - 2.1e-14 52.9 6.0 8.8e-14 50.9 0.8 3.2 3 1 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 ETO33039.1 - 9.7e-06 25.6 1.6 9.7e-06 25.6 1.1 2.6 3 0 0 3 3 3 1 Syntaxin Sec34 PF04136.10 ETO33039.1 - 0.0003 20.5 5.9 0.0017 18.0 0.6 2.3 2 0 0 2 2 2 1 Sec34-like family RasGAP_C PF03836.10 ETO33039.1 - 0.0089 15.7 1.1 0.0089 15.7 0.8 2.4 2 1 0 2 2 2 1 RasGAP C-terminus DUF4349 PF14257.1 ETO33039.1 - 0.011 14.9 1.4 0.011 14.9 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) DASH_Dam1 PF08653.5 ETO33039.1 - 0.046 13.4 0.4 6.3 6.6 0.1 2.6 2 0 0 2 2 2 0 DASH complex subunit Dam1 Spectrin PF00435.16 ETO33039.1 - 0.048 13.9 6.1 1.7 8.9 0.2 2.9 2 1 0 2 2 2 0 Spectrin repeat MCPsignal PF00015.16 ETO33039.1 - 0.049 13.1 8.9 0.037 13.5 2.2 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Mod_r PF07200.8 ETO33039.1 - 0.063 13.1 7.7 0.49 10.3 1.0 2.6 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein RNase_T PF00929.19 ETO33039.1 - 0.093 13.0 0.9 0.28 11.4 0.1 2.0 1 1 1 2 2 2 0 Exonuclease BLOC1_2 PF10046.4 ETO33039.1 - 0.34 11.0 11.1 2.9 8.0 0.1 3.7 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.7 ETO33039.1 - 0.69 9.6 12.6 3.4 7.4 0.9 3.2 2 1 1 3 3 3 0 Laminin Domain II IZUMO PF15005.1 ETO33039.1 - 1.4 8.9 5.7 2.1 8.3 0.5 2.5 2 1 0 2 2 2 0 Izumo sperm-egg fusion Ead_Ea22 PF13935.1 ETO33039.1 - 3.1 8.1 5.8 1 9.6 1.5 2.1 2 1 0 2 2 2 0 Ead/Ea22-like protein Spore_II_R PF09551.5 ETO33039.1 - 6.1 6.8 10.3 1.9 8.5 0.7 3.1 2 1 1 3 3 3 0 Stage II sporulation protein R (spore_II_R) PhyH PF05721.8 ETO33040.1 - 3.3e-05 24.0 0.2 7.4e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) AraC_binding PF02311.14 ETO33040.1 - 0.099 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain FGF PF00167.13 ETO33041.1 - 7.8e-05 22.4 0.6 0.072 12.8 0.1 2.5 1 1 0 2 2 2 2 Fibroblast growth factor Fascin PF06268.8 ETO33041.1 - 0.0084 16.2 0.0 0.025 14.6 0.0 1.8 1 0 0 1 1 1 1 Fascin domain EFG_IV PF03764.13 ETO33041.1 - 0.082 12.4 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Elongation factor G, domain IV NKAIN PF05640.9 ETO33042.1 - 3.8 6.4 8.3 6.2 5.7 5.8 1.4 1 0 0 1 1 1 0 Na,K-Atpase Interacting protein FAD_binding_8 PF08022.7 ETO33043.1 - 4.3e-25 87.6 0.0 8e-25 86.7 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 ETO33043.1 - 1e-13 51.4 10.7 2.4e-13 50.2 7.4 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 ETO33043.1 - 6.6e-05 22.9 0.0 0.00017 21.6 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain MreB_Mbl PF06723.8 ETO33044.1 - 0.06 11.9 0.0 0.087 11.4 0.0 1.1 1 0 0 1 1 1 0 MreB/Mbl protein Kelch_6 PF13964.1 ETO33045.1 - 8.1e-06 25.7 3.9 0.044 13.9 0.0 3.9 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO33045.1 - 0.0074 15.8 8.4 0.97 9.0 0.0 4.4 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO33045.1 - 0.025 14.3 5.1 4.2 7.3 0.0 3.8 4 0 0 4 4 4 0 Kelch motif Kelch_3 PF13415.1 ETO33045.1 - 0.33 11.1 1.2 7.2 6.9 0.0 3.4 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO33045.1 - 0.51 10.1 5.4 1.1 9.0 0.0 3.5 4 1 1 5 5 5 0 Galactose oxidase, central domain WD40 PF00400.27 ETO33046.1 - 9.4e-76 247.2 14.8 2.2e-12 46.3 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat PD40 PF07676.7 ETO33046.1 - 2.5e-07 30.2 4.5 0.28 10.8 0.1 5.9 6 0 0 6 6 6 3 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 ETO33046.1 - 3.9e-06 26.1 0.5 0.0072 15.4 0.0 3.2 1 1 2 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 ETO33046.1 - 7.5e-06 24.3 5.1 0.004 15.3 0.1 4.2 1 1 3 4 4 4 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO33046.1 - 0.00023 20.6 0.3 0.00069 19.1 0.1 2.0 1 1 1 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO33046.1 - 0.00073 17.9 0.2 1 7.6 0.0 2.8 1 1 3 4 4 4 4 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 ETO33046.1 - 0.0057 15.4 0.1 0.12 11.2 0.0 2.3 1 1 0 2 2 2 1 Coatomer WD associated region Resistin PF06954.6 ETO33046.1 - 0.007 16.6 1.0 4.8 7.5 0.0 3.0 2 1 1 3 3 3 2 Resistin IKI3 PF04762.7 ETO33046.1 - 0.023 12.5 0.1 0.05 11.4 0.0 1.6 2 0 0 2 2 2 0 IKI3 family SGL PF08450.7 ETO33046.1 - 0.024 13.9 0.4 6 6.1 0.0 3.1 1 1 1 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region Nucleoporin_N PF08801.6 ETO33046.1 - 0.044 12.5 6.2 0.046 12.4 0.3 3.4 1 1 0 2 2 2 0 Nup133 N terminal like Herpes_UL7 PF01677.11 ETO33047.1 - 0.021 14.1 1.9 0.025 13.8 1.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL7 like Lung_7-TM_R PF06814.8 ETO33047.1 - 0.1 11.5 9.9 0.15 11.0 6.9 1.3 1 0 0 1 1 1 0 Lung seven transmembrane receptor WD40 PF00400.27 ETO33048.1 - 1.3e-49 164.3 18.0 2.7e-10 39.7 0.3 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO33048.1 - 2.5e-07 29.2 0.3 0.028 12.5 0.2 3.8 1 1 1 3 3 3 3 Nucleoporin Nup120/160 DUF2278 PF10042.4 ETO33049.1 - 0.0074 16.0 5.1 0.012 15.3 3.5 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2278) DUF1644 PF07800.7 ETO33049.1 - 0.0093 15.8 14.1 0.0093 15.8 9.8 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1644) Terminase_6 PF03237.10 ETO33049.1 - 0.048 12.4 1.0 0.067 11.9 0.3 1.5 1 1 0 1 1 1 0 Terminase-like family Reo_sigmaC PF04582.7 ETO33049.1 - 0.56 9.3 2.6 0.79 8.8 1.1 1.7 2 1 0 2 2 2 0 Reovirus sigma C capsid protein Surfac_D-trimer PF09006.6 ETO33049.1 - 2.1 8.1 7.8 0.43 10.3 0.8 2.8 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation DUF1515 PF07439.6 ETO33049.1 - 2.8 7.7 6.8 0.85 9.4 1.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) TEX13 PF15186.1 ETO33049.1 - 2.9 7.4 19.7 0.11 12.1 6.3 2.8 1 1 2 3 3 3 0 Testis-expressed sequence 13 protein family DUF4200 PF13863.1 ETO33049.1 - 4.5 7.2 38.8 0.19 11.7 17.5 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) DUF1664 PF07889.7 ETO33049.1 - 5.9 6.7 20.9 0.036 13.8 1.9 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 ETO33049.1 - 6.4 5.3 36.2 2.7 6.5 15.3 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1625 PF07787.7 ETO33050.1 - 6.3e-08 32.1 0.4 6.3e-08 32.1 0.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1625) TPR_12 PF13424.1 ETO33050.1 - 1.1e-06 28.4 0.2 2.9e-06 27.1 0.2 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF1625 PF07787.7 ETO33051.1 - 3.3e-06 26.5 0.7 5.8e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1625) BSP_II PF05432.6 ETO33051.1 - 0.056 12.7 14.9 0.081 12.1 10.3 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF2457 PF10446.4 ETO33051.1 - 0.062 12.0 6.2 0.075 11.7 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 ETO33051.1 - 6 5.2 14.9 8 4.8 10.3 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 ETO33051.1 - 7 4.5 11.6 8.9 4.2 8.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 ETO33051.1 - 7.4 4.1 9.9 9.3 3.7 6.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Utp13 PF08625.6 ETO33054.1 - 0.072 12.7 0.8 0.2 11.2 0.1 1.7 1 1 1 2 2 2 0 Utp13 specific WD40 associated domain Helicase_Sgs1 PF11408.3 ETO33054.1 - 0.11 12.3 0.6 0.18 11.6 0.1 1.6 2 0 0 2 2 2 0 Sgs1 RecQ helicase DUF217 PF02697.9 ETO33054.1 - 0.39 11.0 3.0 0.66 10.2 0.2 2.5 1 1 2 3 3 3 0 Uncharacterized ACR, COG1753 DUF3196 PF11428.3 ETO33055.1 - 0.06 12.6 1.6 0.46 9.7 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3196) Aha1_N PF09229.6 ETO33055.1 - 0.14 12.0 0.0 0.22 11.3 0.0 1.4 1 1 0 1 1 1 0 Activator of Hsp90 ATPase, N-terminal MIT PF04212.13 ETO33058.1 - 1.7e-09 37.4 1.9 3.4e-09 36.4 1.3 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA PF00004.24 ETO33058.1 - 0.0019 18.3 0.1 0.0052 16.9 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 ETO33058.1 - 0.0093 15.3 0.1 0.018 14.4 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 ETO33058.1 - 0.017 14.8 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 ETO33058.1 - 0.027 13.6 0.1 0.065 12.3 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 ETO33058.1 - 0.079 13.7 0.1 0.47 11.2 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.9 ETO33058.1 - 0.09 12.5 0.0 0.28 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETO33058.1 - 0.11 12.6 0.0 0.35 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETO33058.1 - 0.12 12.3 0.0 0.39 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Pkinase PF00069.20 ETO33059.1 - 4.9e-56 189.7 0.0 9.7e-56 188.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO33059.1 - 5.9e-26 91.0 0.0 1.7e-25 89.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 ETO33059.1 - 4e-25 85.1 9.7 1e-06 27.5 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 ETO33059.1 - 6.8e-23 80.5 6.4 3.4e-11 43.1 0.4 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO33059.1 - 1.1e-19 68.4 4.8 9.2e-07 28.2 0.0 5.1 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 ETO33059.1 - 1e-17 62.5 9.4 2e-07 30.0 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 ETO33059.1 - 5.3e-17 61.1 6.2 1.6e-07 30.8 0.4 4.5 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 ETO33059.1 - 2.6e-09 37.1 3.6 2.7e-05 24.1 0.1 3.7 1 1 3 4 4 4 4 Secreted protein acidic and rich in cysteine Ca binding region Kdo PF06293.9 ETO33059.1 - 5.3e-06 25.6 0.0 1.2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 ETO33059.1 - 6e-05 22.4 0.0 0.00015 21.2 0.0 1.6 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 ETO33059.1 - 0.00023 21.0 0.0 0.011 15.4 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 ETO33059.1 - 0.00081 18.4 0.0 0.0031 16.5 0.0 1.9 2 1 0 2 2 2 1 Kinase-like EF-hand_9 PF14658.1 ETO33059.1 - 0.018 14.9 0.2 0.18 11.7 0.1 2.7 2 1 0 2 2 2 0 EF-hand domain EF-hand_2 PF09068.6 ETO33059.1 - 0.025 14.6 0.0 0.069 13.2 0.0 1.7 1 0 0 1 1 1 0 EF hand PABP PF00658.13 ETO33060.1 - 0.0013 18.3 0.1 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain zf-TRAF PF02176.13 ETO33062.1 - 1.5e-06 28.4 6.6 6.6e-06 26.3 4.6 2.2 1 0 0 1 1 1 1 TRAF-type zinc finger Ribosomal_S14 PF00253.16 ETO33062.1 - 0.071 12.4 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S14p/S29e Mgr1 PF08602.5 ETO33062.1 - 0.28 10.1 8.5 0.39 9.6 5.9 1.2 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit Peroxin-13_N PF04088.8 ETO33062.1 - 0.51 10.2 4.0 0.86 9.5 2.8 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region CPSF100_C PF13299.1 ETO33062.1 - 1 9.4 8.7 2 8.6 6.0 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal IncA PF04156.9 ETO33062.1 - 7.4 6.1 18.6 13 5.3 12.9 1.3 1 0 0 1 1 1 0 IncA protein Corona_nucleoca PF00937.13 ETO33063.1 - 0.0078 15.2 1.1 0.011 14.6 0.8 1.2 1 0 0 1 1 1 1 Coronavirus nucleocapsid protein DUF1509 PF07420.6 ETO33063.1 - 0.018 14.3 2.6 0.022 14.0 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) ACP PF06857.6 ETO33063.1 - 0.022 14.6 0.1 0.041 13.8 0.1 1.4 1 0 0 1 1 1 0 Malonate decarboxylase delta subunit (MdcD) FAM91_C PF14648.1 ETO33063.1 - 0.031 13.1 2.3 0.24 10.1 0.0 2.1 2 0 0 2 2 2 0 FAM91 C-terminus Apis_Csd PF11671.3 ETO33063.1 - 0.54 10.0 8.8 1.1 9.0 6.1 1.4 1 0 0 1 1 1 0 Complementary sex determiner protein STE2 PF02116.10 ETO33064.1 - 0.11 11.5 0.4 0.11 11.4 0.3 1.0 1 0 0 1 1 1 0 Fungal pheromone mating factor STE2 GPCR GRIP PF01465.15 ETO33064.1 - 7.9 6.0 8.8 4.9 6.7 0.8 2.9 2 1 1 3 3 3 0 GRIP domain DHC_N2 PF08393.8 ETO33065.1 - 9.5e-13 47.4 9.7 9.5e-13 47.4 6.7 3.1 2 1 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 DUF2564 PF10819.3 ETO33065.1 - 0.099 12.7 5.9 2.8 8.1 0.3 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2564) Glyco_transf_92 PF01697.22 ETO33066.1 - 0.016 14.4 0.0 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 92 Glyco_transf_25 PF01755.12 ETO33067.1 - 0.0004 20.0 0.5 0.031 13.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) MerB PF03243.10 ETO33067.1 - 0.074 12.8 0.1 15 5.4 0.1 2.2 2 0 0 2 2 2 0 Alkylmercury lyase WD40 PF00400.27 ETO33068.1 - 3.4e-27 93.2 11.8 1e-09 37.8 0.7 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO33068.1 - 7.1e-06 24.4 3.6 0.0024 16.1 0.0 3.5 2 2 2 4 4 4 3 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO33068.1 - 0.15 12.2 3.1 63 3.9 0.0 3.5 3 0 0 3 3 3 0 Kelch motif WD40 PF00400.27 ETO33069.1 - 2.4e-28 96.9 5.4 1.6e-09 37.2 0.5 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO33069.1 - 4.2e-06 25.1 1.0 0.046 11.8 0.0 2.7 1 1 2 3 3 3 2 Nucleoporin Nup120/160 PSI PF01437.20 ETO33069.1 - 0.011 15.9 1.0 0.024 14.7 0.7 1.6 1 1 0 1 1 1 0 Plexin repeat Nucleoporin_N PF08801.6 ETO33069.1 - 0.035 12.8 0.1 0.071 11.8 0.1 1.6 1 1 0 1 1 1 0 Nup133 N terminal like WD40 PF00400.27 ETO33071.1 - 4.3e-17 61.2 6.3 3.9e-11 42.3 0.3 2.6 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO33071.1 - 0.0002 19.6 1.0 0.084 10.9 0.1 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Ricin_B_lectin PF00652.17 ETO33071.1 - 0.13 12.3 3.4 0.16 12.0 2.4 1.2 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain ET PF01684.11 ETO33071.1 - 0.18 11.8 1.7 0.24 11.4 1.2 1.3 1 0 0 1 1 1 0 ET module VWA_2 PF13519.1 ETO33072.1 - 4.7e-05 23.5 0.1 0.01 15.9 0.0 2.3 2 1 0 2 2 2 2 von Willebrand factor type A domain VWA PF00092.23 ETO33072.1 - 0.003 17.3 0.0 0.77 9.4 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.1 ETO33072.1 - 0.053 13.2 0.0 0.18 11.5 0.0 1.8 2 1 0 2 2 2 0 von Willebrand factor type A domain MarR PF01047.17 ETO33072.1 - 0.081 12.6 0.0 0.78 9.4 0.0 2.3 2 0 0 2 2 2 0 MarR family SPRY PF00622.23 ETO33073.1 - 1.1e-23 83.6 3.4 2.6e-13 50.1 0.9 2.3 2 0 0 2 2 2 2 SPRY domain GDE_N PF12439.3 ETO33073.1 - 0.054 12.7 0.0 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme N terminal Ras PF00071.17 ETO33074.1 - 1.4e-25 89.5 0.7 1.7e-25 89.3 0.5 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO33074.1 - 2.5e-05 24.7 0.2 5e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO33074.1 - 0.01 15.0 0.2 0.015 14.5 0.1 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family Aminotran_1_2 PF00155.16 ETO33075.1 - 6e-19 68.2 0.0 8.1e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 ETO33075.1 - 3e-06 26.5 0.0 5.5e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 ETO33075.1 - 0.015 13.6 0.0 0.029 12.6 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Caprin-1_C PF12287.3 ETO33075.1 - 0.016 14.5 2.2 0.027 13.8 1.6 1.3 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term FAD_binding_6 PF00970.19 ETO33076.1 - 1.4e-08 34.7 0.0 1.5e-05 25.0 0.0 2.8 3 0 0 3 3 3 2 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 ETO33076.1 - 1.7e-08 34.9 0.0 5e-08 33.4 0.0 1.8 1 1 1 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 ETO33076.1 - 0.00079 19.3 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ribosomal_L50 PF10501.4 ETO33078.1 - 0.00098 19.0 0.3 0.0015 18.5 0.2 1.3 1 0 0 1 1 1 1 Ribosomal subunit 39S RNaseH_C PF09293.5 ETO33078.1 - 0.12 12.2 1.3 0.13 12.1 0.2 1.6 2 0 0 2 2 2 0 T4 RNase H, C terminal YjgP_YjgQ PF03739.9 ETO33079.1 - 0.00074 18.3 1.6 0.001 17.8 1.1 1.2 1 0 0 1 1 1 1 Predicted permease YjgP/YjgQ family DUF912 PF06024.7 ETO33079.1 - 0.0073 16.3 0.7 0.024 14.7 0.2 2.0 1 1 1 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) CcmB PF03379.8 ETO33079.1 - 0.031 13.5 2.7 0.054 12.7 1.9 1.3 1 0 0 1 1 1 0 CcmB protein CbiQ PF02361.11 ETO33079.1 - 0.06 12.9 3.2 0.077 12.5 2.2 1.2 1 0 0 1 1 1 0 Cobalt transport protein MARVEL PF01284.18 ETO33079.1 - 0.087 12.6 7.0 0.13 12.1 4.8 1.2 1 0 0 1 1 1 0 Membrane-associating domain GSG-1 PF07803.6 ETO33079.1 - 0.095 12.3 1.7 0.36 10.4 0.9 1.9 1 1 1 2 2 2 0 GSG1-like protein Spo7 PF03907.8 ETO33079.1 - 0.13 11.8 3.5 0.17 11.4 2.4 1.2 1 0 0 1 1 1 0 Spo7-like protein Sigma_reg_N PF13800.1 ETO33079.1 - 0.65 10.0 4.2 0.48 10.4 0.7 2.2 2 1 0 2 2 2 0 Sigma factor regulator N-terminal DUF4293 PF14126.1 ETO33079.1 - 0.82 9.5 6.7 0.6 10.0 3.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) DUF3815 PF12821.2 ETO33079.1 - 1.4 8.8 7.4 8 6.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3815) EpsG PF14897.1 ETO33079.1 - 10 4.9 19.8 40 2.9 13.6 1.9 1 1 0 1 1 1 0 EpsG family Bromodomain PF00439.20 ETO33080.1 - 4.6e-15 55.2 0.0 1.1e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Bromodomain DUF2987 PF11205.3 ETO33081.1 - 0.021 14.5 0.4 0.025 14.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2987) ZZ PF00569.12 ETO33082.1 - 0.0011 18.4 1.8 0.0011 18.4 1.2 1.7 2 0 0 2 2 2 1 Zinc finger, ZZ type DDE_Tnp_IS240 PF13610.1 ETO33082.1 - 0.067 13.1 1.3 0.091 12.7 0.9 1.3 1 0 0 1 1 1 0 DDE domain Imm35 PF15581.1 ETO33083.1 - 0.37 10.8 2.3 6.3 6.9 0.1 2.3 2 0 0 2 2 2 0 Immunity protein 35 WD40 PF00400.27 ETO33084.1 - 4.8e-44 146.7 3.6 1.1e-10 40.9 0.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO33084.1 - 7.1e-08 31.0 4.0 0.00087 17.5 0.3 3.9 3 1 0 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO33084.1 - 6.5e-05 21.3 0.9 0.024 12.9 0.0 2.6 1 1 1 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO33084.1 - 0.0003 19.6 6.1 0.72 8.5 0.0 4.0 2 2 2 4 4 4 3 Nup133 N terminal like IKI3 PF04762.7 ETO33084.1 - 0.0014 16.5 1.8 1.7 6.3 0.0 3.0 1 1 2 3 3 3 3 IKI3 family PQQ_2 PF13360.1 ETO33084.1 - 0.002 17.6 0.1 0.018 14.5 0.0 2.4 2 1 0 2 2 2 1 PQQ-like domain Formyl_trans_C PF02911.13 ETO33084.1 - 0.093 12.8 0.2 9 6.4 0.0 3.6 2 1 1 4 4 4 0 Formyl transferase, C-terminal domain WD40 PF00400.27 ETO33085.1 - 9.1e-60 196.5 10.3 2.1e-11 43.2 0.0 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO33085.1 - 5.6e-07 29.4 0.4 6.8e-05 22.6 0.1 2.9 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO33085.1 - 1e-05 23.9 5.8 0.66 8.0 0.1 4.4 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO33085.1 - 3.9e-05 22.5 5.5 0.21 10.2 0.7 3.7 1 1 3 4 4 4 2 Nup133 N terminal like PQQ_2 PF13360.1 ETO33085.1 - 0.001 18.5 0.7 0.042 13.2 0.1 2.6 2 1 0 3 3 3 1 PQQ-like domain Coatomer_WDAD PF04053.9 ETO33085.1 - 0.0016 17.2 1.3 0.0058 15.4 0.2 2.2 1 1 1 2 2 2 1 Coatomer WD associated region PD40 PF07676.7 ETO33085.1 - 0.004 16.7 2.1 13 5.6 0.0 5.2 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO33085.1 - 0.008 14.5 1.8 1.7 6.8 0.0 2.6 1 1 3 4 4 4 3 Cytochrome D1 heme domain CRT10 PF08728.5 ETO33085.1 - 0.013 13.5 0.8 0.085 10.8 0.0 2.0 1 1 0 2 2 2 0 CRT10 Lactonase PF10282.4 ETO33085.1 - 0.035 13.1 1.2 15 4.5 0.0 3.5 2 1 2 4 4 4 0 Lactonase, 7-bladed beta-propeller IKI3 PF04762.7 ETO33085.1 - 0.053 11.3 0.1 8.1 4.1 0.0 2.5 2 1 1 3 3 3 0 IKI3 family DUF1513 PF07433.6 ETO33085.1 - 0.054 12.3 0.0 6.7 5.5 0.0 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF1513) WD40 PF00400.27 ETO33086.1 - 1.3e-49 164.3 11.1 1.3e-09 37.5 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO33086.1 - 2.9e-09 35.6 1.5 0.0036 15.5 0.0 4.4 1 1 3 4 4 4 4 Nucleoporin Nup120/160 DHC PF09626.5 ETO33087.1 - 0.012 16.3 0.1 0.026 15.1 0.1 1.6 1 0 0 1 1 1 0 Dihaem cytochrome c S10_plectin PF03501.10 ETO33087.1 - 0.054 13.3 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Plectin/S10 domain RESP18 PF14948.1 ETO33087.1 - 0.13 12.3 0.3 1.1 9.3 0.0 2.3 1 1 1 2 2 2 0 RESP18 domain WD40 PF00400.27 ETO33088.1 - 9.2e-61 199.7 23.1 1.3e-11 43.8 0.2 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO33088.1 - 5.3e-08 31.4 12.8 0.058 11.5 0.1 5.7 2 2 3 5 5 5 5 Nucleoporin Nup120/160 TPR_12 PF13424.1 ETO33089.1 - 2.9e-16 59.1 0.0 5.9e-10 38.9 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO33089.1 - 9.6e-10 37.9 0.1 3.1e-09 36.3 0.1 1.8 1 0 0 1 1 1 1 TPR repeat TPR_10 PF13374.1 ETO33089.1 - 4e-07 29.7 0.0 0.0079 16.0 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO33089.1 - 1.2e-06 27.8 0.1 0.035 13.8 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO33089.1 - 1.1e-05 24.7 7.4 0.014 14.9 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat MIT PF04212.13 ETO33089.1 - 0.00012 21.9 4.7 0.045 13.6 0.1 4.3 4 2 1 5 5 5 2 MIT (microtubule interacting and transport) domain TPR_8 PF13181.1 ETO33089.1 - 0.00018 21.0 7.1 0.0062 16.2 0.5 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO33089.1 - 0.00052 19.7 4.8 0.02 14.7 0.2 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat MFS_1 PF07690.11 ETO33090.1 - 3.2e-11 42.5 14.0 3.2e-11 42.5 9.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETO33091.1 - 8.7e-14 50.9 5.4 1.1e-13 50.6 3.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETO33091.1 - 6e-07 28.4 6.3 7.8e-07 28.1 4.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 ETO33091.1 - 0.00091 17.7 2.1 0.0012 17.3 1.3 1.3 1 1 0 1 1 1 1 MFS/sugar transport protein DUF843 PF05814.6 ETO33091.1 - 0.79 9.5 0.0 0.79 9.5 0.0 2.5 3 0 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) FPL PF09758.4 ETO33092.1 - 8.6e-37 126.1 15.4 1.5e-32 112.4 7.2 2.3 1 1 1 2 2 2 2 Uncharacterised conserved protein SR-25 PF10500.4 ETO33092.1 - 0.027 13.9 16.6 0.05 13.0 11.5 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Shisa PF13908.1 ETO33093.1 - 0.0034 17.5 0.1 0.0034 17.5 0.1 2.9 3 0 0 3 3 3 1 Wnt and FGF inhibitory regulator DUF3643 PF12356.3 ETO33093.1 - 0.012 14.9 0.3 0.06 12.6 0.1 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3643) Methyltransf_12 PF08242.7 ETO33094.1 - 0.077 13.4 0.3 0.077 13.4 0.2 1.5 2 0 0 2 2 2 0 Methyltransferase domain Apis_Csd PF11671.3 ETO33094.1 - 0.14 11.9 2.5 0.18 11.5 1.7 1.2 1 0 0 1 1 1 0 Complementary sex determiner protein Glyco_hydro_1 PF00232.13 ETO33094.1 - 0.15 10.2 0.6 0.16 10.1 0.4 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 Arm PF00514.18 ETO33095.1 - 0.0058 16.4 0.3 12 5.8 0.1 3.8 4 1 0 4 4 4 2 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.9 ETO33095.1 - 0.083 11.9 0.1 0.15 11.1 0.1 1.5 1 1 0 1 1 1 0 V-ATPase subunit H DUF4079 PF13301.1 ETO33096.1 - 8.6 6.3 10.7 1.3e+02 2.4 7.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) RRF_GI PF12614.3 ETO33097.1 - 0.014 15.2 0.5 0.02 14.6 0.3 1.3 1 0 0 1 1 1 0 Ribosome recycling factor IMD PF08397.6 ETO33097.1 - 0.022 14.0 2.0 0.029 13.6 1.4 1.2 1 0 0 1 1 1 0 IRSp53/MIM homology domain Zot PF05707.7 ETO33097.1 - 0.033 13.6 0.8 0.034 13.6 0.6 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) IncA PF04156.9 ETO33097.1 - 0.12 11.9 1.3 0.14 11.7 0.9 1.1 1 0 0 1 1 1 0 IncA protein Mcm10 PF09332.6 ETO33097.1 - 0.19 11.0 4.3 0.21 10.9 3.0 1.1 1 0 0 1 1 1 0 Mcm10 replication factor YgaB PF14182.1 ETO33097.1 - 0.4 10.9 2.8 0.32 11.2 0.4 1.8 1 1 1 2 2 2 0 YgaB-like protein DUF2762 PF10960.3 ETO33097.1 - 1.4 8.6 3.6 2.5 7.8 2.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2762) RNA_pol_Rpb4 PF03874.11 ETO33098.1 - 0.025 14.5 0.5 0.034 14.1 0.4 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb4 DUF879 PF05947.7 ETO33098.1 - 0.15 10.3 0.0 0.17 10.1 0.0 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF879) PaaSYMP PF14738.1 ETO33098.1 - 0.23 11.1 7.0 0.29 10.8 4.8 1.0 1 0 0 1 1 1 0 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 TIR PF01582.15 ETO33098.1 - 0.44 9.9 5.2 0.48 9.8 3.6 1.1 1 0 0 1 1 1 0 TIR domain DUF3767 PF12597.3 ETO33098.1 - 1.5 8.4 4.9 2 8.1 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) PBP1_TM PF14812.1 ETO33099.1 - 0.15 12.3 8.9 0.17 12.1 6.2 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4637 PF15470.1 ETO33099.1 - 0.64 9.6 3.1 0.7 9.4 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) TRAP_alpha PF03896.11 ETO33099.1 - 0.73 8.7 5.5 0.7 8.8 3.8 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4024 PF13216.1 ETO33099.1 - 0.73 9.6 2.7 0.61 9.9 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4024) DUF4604 PF15377.1 ETO33099.1 - 1.8 8.7 14.0 2.2 8.4 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) RNA_pol_Rpc4 PF05132.9 ETO33099.1 - 4.2 7.3 6.6 4.9 7.1 4.6 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Sigma70_ner PF04546.8 ETO33099.1 - 4.3 6.8 10.8 4.3 6.8 7.5 1.0 1 0 0 1 1 1 0 Sigma-70, non-essential region MDM1 PF15501.1 ETO33099.1 - 9.1 5.0 8.4 9.7 4.9 5.8 1.0 1 0 0 1 1 1 0 Nuclear protein MDM1 Presenilin PF01080.12 ETO33100.1 - 0.82 8.4 3.6 0.84 8.3 2.5 1.1 1 0 0 1 1 1 0 Presenilin MGDG_synth PF06925.6 ETO33101.1 - 0.035 14.0 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase Colicin-DNase PF12639.2 ETO33101.1 - 0.07 13.3 0.8 0.1 12.8 0.0 1.7 2 1 0 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin DUF2897 PF11446.3 ETO33102.1 - 0.18 11.6 0.1 0.18 11.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) C2 PF00168.25 ETO33103.1 - 6e-11 42.0 0.0 1.1e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain 2OG-FeII_Oxy_3 PF13640.1 ETO33104.1 - 1.5e-10 41.4 0.1 2.6e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 ETO33104.1 - 1.7e-05 24.3 0.1 3.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Abhydrolase_6 PF12697.2 ETO33105.1 - 3.7e-11 43.3 0.0 4.7e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETO33105.1 - 0.021 14.5 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Kelch_6 PF13964.1 ETO33106.1 - 1.9e-09 37.2 1.1 0.0021 18.1 0.1 4.6 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO33106.1 - 3.9e-09 35.9 1.8 2.6e-06 26.8 0.2 4.2 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO33106.1 - 1.3e-07 31.3 0.6 0.00049 19.8 0.0 3.5 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO33106.1 - 7e-07 28.7 4.1 0.00062 19.4 0.1 4.9 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.1 ETO33106.1 - 5.9e-05 23.1 0.4 0.0091 16.1 0.0 3.6 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO33106.1 - 0.0049 16.7 7.1 0.051 13.5 0.0 4.4 6 0 0 6 6 6 1 Kelch motif SMI1_KNR4 PF09346.5 ETO33106.1 - 0.33 10.9 3.8 0.54 10.2 0.6 2.5 2 1 1 3 3 3 0 SMI1 / KNR4 family (SUKH-1) Oxysterol_BP PF01237.13 ETO33107.1 - 0.007 14.8 0.7 0.012 14.1 0.5 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein Methyltransf_11 PF08241.7 ETO33108.1 - 1e-14 54.7 0.1 3.3e-14 53.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETO33108.1 - 4.9e-12 45.8 0.0 8.2e-12 45.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETO33108.1 - 3.1e-11 43.5 0.1 8.9e-11 42.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO33108.1 - 4.8e-11 42.9 0.0 1e-10 41.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 ETO33108.1 - 5.9e-11 42.0 0.2 1.1e-10 41.1 0.2 1.5 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.2 ETO33108.1 - 7.7e-11 42.5 0.0 1.4e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO33108.1 - 2.3e-10 40.2 0.5 3.6e-10 39.6 0.3 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETO33108.1 - 9.5e-08 32.0 0.0 1.6e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETO33108.1 - 4.9e-07 29.0 0.2 3.4e-06 26.3 0.1 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.7 ETO33108.1 - 0.00049 19.0 0.1 0.0014 17.5 0.0 1.7 2 0 0 2 2 2 1 DREV methyltransferase MTS PF05175.9 ETO33108.1 - 0.0021 17.4 0.0 0.0039 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 ETO33108.1 - 0.0032 17.1 0.1 0.0067 16.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 ETO33108.1 - 0.0038 17.2 0.0 0.0067 16.4 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase RrnaAD PF00398.15 ETO33108.1 - 0.026 13.5 0.0 0.057 12.4 0.0 1.6 1 1 0 1 1 1 0 Ribosomal RNA adenine dimethylase Pox_MCEL PF03291.11 ETO33108.1 - 0.043 12.6 0.1 0.065 12.0 0.1 1.3 1 0 0 1 1 1 0 mRNA capping enzyme Mrr_cat PF04471.7 ETO33109.1 - 1.7e-19 69.7 0.0 3.5e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Restriction endonuclease Myb_DNA-binding PF00249.26 ETO33109.1 - 0.00038 20.4 1.2 0.00089 19.2 0.9 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain HET PF06985.6 ETO33109.1 - 0.0077 16.4 0.2 0.0077 16.4 0.1 2.4 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Myb_DNA-bind_6 PF13921.1 ETO33109.1 - 0.067 13.3 4.4 0.24 11.5 3.0 2.0 1 0 0 1 1 1 0 Myb-like DNA-binding domain BNIP2 PF12496.3 ETO33109.1 - 0.19 11.9 5.4 3.1 7.9 0.4 2.6 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Pkinase PF00069.20 ETO33110.1 - 5.8e-11 42.0 0.0 1.2e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain RGS PF00615.14 ETO33110.1 - 1.8e-08 34.5 0.6 0.00071 19.6 0.0 3.2 3 0 0 3 3 3 2 Regulator of G protein signaling domain Pkinase_Tyr PF07714.12 ETO33110.1 - 0.029 13.4 0.2 0.067 12.2 0.0 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase TFCD_C PF12612.3 ETO33111.1 - 0.011 15.1 0.0 0.026 13.9 0.0 1.5 2 0 0 2 2 2 0 Tubulin folding cofactor D C terminal PBP1_TM PF14812.1 ETO33112.1 - 2.2 8.6 9.8 4.5 7.6 6.8 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Kelch_6 PF13964.1 ETO33113.1 - 1.1e-08 34.9 6.3 0.013 15.6 0.1 5.2 4 1 1 5 5 5 3 Kelch motif Kelch_5 PF13854.1 ETO33113.1 - 9.7e-08 31.8 4.5 0.46 10.4 0.2 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 ETO33113.1 - 1e-07 31.3 8.1 0.00042 19.8 0.5 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO33113.1 - 1.1e-07 31.3 2.7 0.00027 20.5 0.1 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO33113.1 - 1.9e-06 27.5 1.7 0.013 15.2 0.0 4.4 4 1 1 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO33113.1 - 0.002 18.2 1.9 4.6 7.5 0.0 4.7 6 0 0 6 6 6 1 Galactose oxidase, central domain zf-RING_UBOX PF13445.1 ETO33113.1 - 0.0078 15.9 0.3 0.045 13.4 0.0 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-AD PF07776.10 ETO33114.1 - 0.038 13.9 0.8 0.27 11.2 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) Kelch_1 PF01344.20 ETO33116.1 - 4e-13 48.6 3.2 4.4e-08 32.5 0.5 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.1 ETO33116.1 - 4.3e-08 32.9 0.1 0.0047 16.8 0.1 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO33116.1 - 1.2e-07 31.5 2.6 0.02 15.0 0.3 3.9 3 1 1 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO33116.1 - 2.5e-05 23.8 1.1 0.09 12.5 0.1 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO33116.1 - 0.00021 20.9 0.0 0.88 9.3 0.1 2.9 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO33116.1 - 0.00026 21.0 0.1 0.019 15.0 0.0 3.0 3 0 0 3 3 3 1 Galactose oxidase, central domain Copper-bind PF00127.15 ETO33116.1 - 0.011 15.9 0.4 0.032 14.4 0.1 1.9 2 0 0 2 2 2 0 Copper binding proteins, plastocyanin/azurin family WD40 PF00400.27 ETO33117.1 - 2.7e-09 36.5 7.6 2.9e-05 23.7 1.2 3.4 4 1 0 4 4 4 2 WD domain, G-beta repeat TPR_11 PF13414.1 ETO33118.1 - 2.1e-09 36.8 10.3 0.015 14.9 0.7 4.0 4 0 0 4 4 4 3 TPR repeat TPR_19 PF14559.1 ETO33118.1 - 1.2e-06 28.7 16.2 0.0011 19.2 3.0 3.9 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO33118.1 - 5.3e-06 26.5 11.5 0.36 11.5 0.2 5.6 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_15 PF13429.1 ETO33118.1 - 2.6e-05 23.4 4.6 0.017 14.1 1.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO33118.1 - 2.6e-05 24.7 11.7 0.049 14.3 0.4 4.5 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO33118.1 - 2.9e-05 23.6 14.6 0.69 9.9 0.0 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO33118.1 - 0.00084 18.8 8.1 0.68 9.6 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO33118.1 - 0.046 13.9 1.5 0.41 10.9 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO33118.1 - 0.11 12.3 4.7 0.37 10.6 0.5 3.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.1 ETO33118.1 - 0.17 12.0 8.3 1.2 9.2 0.4 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETO33118.1 - 0.32 10.8 2.6 67 3.6 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETO33118.1 - 1.2 9.1 12.9 3.1 7.8 0.8 4.2 2 1 1 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 ETO33118.1 - 3 7.7 7.6 4.1 7.3 2.2 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 ETO33118.1 - 3.9 7.6 13.3 5.7 7.1 2.9 3.7 2 1 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 WD40 PF00400.27 ETO33119.1 - 1.9e-33 113.1 12.6 8.5e-12 44.4 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO33119.1 - 2.6e-08 32.4 0.3 0.0085 14.2 0.1 3.1 3 0 0 3 3 3 3 Nucleoporin Nup120/160 zf-RING_5 PF14634.1 ETO33120.1 - 1 9.1 11.6 0.15 11.7 4.5 2.2 2 0 0 2 2 2 0 zinc-RING finger domain Methyltransf_12 PF08242.7 ETO33121.1 - 0.21 12.1 0.9 0.79 10.2 0.6 2.0 1 0 0 1 1 1 0 Methyltransferase domain ERG4_ERG24 PF01222.12 ETO33122.1 - 2.5e-14 52.6 0.9 3e-14 52.3 0.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Kelch_6 PF13964.1 ETO33124.1 - 7.8e-07 29.0 4.7 0.52 10.5 0.0 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 ETO33124.1 - 4.8e-05 22.8 2.1 0.014 14.9 0.0 4.7 5 0 0 5 5 5 1 Kelch motif Kelch_5 PF13854.1 ETO33124.1 - 0.00013 21.8 0.4 4.5 7.3 0.1 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO33124.1 - 0.0019 17.8 8.9 0.021 14.5 0.0 5.0 6 1 0 6 6 6 1 Kelch motif Kelch_3 PF13415.1 ETO33124.1 - 0.0049 16.9 1.8 0.28 11.3 0.0 4.2 6 0 0 6 6 6 1 Galactose oxidase, central domain Ribosomal_L31 PF01197.13 ETO33126.1 - 0.17 11.8 2.8 0.37 10.8 1.9 1.8 1 1 0 1 1 1 0 Ribosomal protein L31 efThoc1 PF11957.3 ETO33128.1 - 4e-17 61.8 2.2 4.8e-17 61.6 1.5 1.0 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor DUF3276 PF11680.3 ETO33128.1 - 0.0081 15.9 0.2 0.012 15.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3276) DUF3466 PF11949.3 ETO33128.1 - 0.11 11.0 0.1 0.14 10.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3466) efThoc1 PF11957.3 ETO33129.1 - 6.3e-07 28.2 0.0 1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor IncA PF04156.9 ETO33130.1 - 0.1 12.1 12.5 0.1 12.1 4.5 2.7 2 0 0 2 2 2 0 IncA protein Chordopox_A13L PF05961.6 ETO33130.1 - 0.34 10.8 6.3 0.077 12.9 0.3 2.9 3 0 0 3 3 3 0 Chordopoxvirus A13L protein Syntaxin-6_N PF09177.6 ETO33130.1 - 3.5 8.1 10.4 22 5.5 4.6 2.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Snapin_Pallidin PF14712.1 ETO33131.1 - 2e-10 40.8 5.3 1.6e-07 31.4 0.5 2.2 1 1 1 2 2 2 2 Snapin/Pallidin PhaP_Bmeg PF09602.5 ETO33131.1 - 0.00097 18.9 5.1 0.0013 18.6 3.6 1.2 1 0 0 1 1 1 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF305 PF03713.8 ETO33131.1 - 0.023 14.5 0.3 0.035 13.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF305) Unstab_antitox PF09720.5 ETO33131.1 - 0.025 14.2 1.8 1.8 8.3 0.9 2.4 1 1 1 2 2 2 0 Putative addiction module component SAE2 PF08573.5 ETO33131.1 - 0.055 14.1 1.5 0.1 13.3 1.0 1.6 1 1 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus DUF2422 PF10337.4 ETO33131.1 - 0.072 11.8 2.9 0.082 11.6 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) DUF1943 PF09172.6 ETO33131.1 - 0.11 11.2 1.3 0.14 11.0 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Prp18 PF02840.10 ETO33131.1 - 0.12 12.2 1.5 0.24 11.1 1.0 1.5 1 0 0 1 1 1 0 Prp18 domain DUF1840 PF08895.6 ETO33131.1 - 0.14 12.2 3.5 0.053 13.5 0.6 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1840) CDC37_N PF03234.9 ETO33131.1 - 0.25 11.6 10.6 0.12 12.7 5.0 1.8 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding DUF4411 PF14367.1 ETO33131.1 - 0.3 10.7 2.9 0.38 10.4 1.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4411) AATF-Che1 PF13339.1 ETO33131.1 - 0.32 11.1 7.9 0.4 10.8 5.0 1.6 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor His_Phos_1 PF00300.17 ETO33131.1 - 0.44 10.6 2.5 0.52 10.3 1.8 1.3 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) SGT1 PF07093.6 ETO33131.1 - 0.55 8.5 7.8 0.63 8.3 5.4 1.1 1 0 0 1 1 1 0 SGT1 protein DUF4407 PF14362.1 ETO33131.1 - 0.62 8.9 4.7 0.75 8.7 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MitMem_reg PF13012.1 ETO33131.1 - 0.93 9.6 6.6 3.4 7.8 4.2 1.9 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function Sigma70_ner PF04546.8 ETO33131.1 - 1.1 8.8 10.0 0.12 11.9 0.6 2.0 1 1 1 2 2 2 0 Sigma-70, non-essential region FadA PF09403.5 ETO33131.1 - 1.4 8.9 15.1 0.079 12.9 4.5 2.2 1 1 1 2 2 2 0 Adhesion protein FadA Ax_dynein_light PF10211.4 ETO33131.1 - 1.9 8.3 12.9 0.28 11.0 5.8 1.7 2 0 0 2 2 2 0 Axonemal dynein light chain Seryl_tRNA_N PF02403.17 ETO33131.1 - 3.8 7.5 14.7 0.86 9.6 5.9 2.2 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain AAA_23 PF13476.1 ETO33131.1 - 3.9 7.7 12.2 5.2 7.3 8.4 1.1 1 0 0 1 1 1 0 AAA domain DUF3464 PF11947.3 ETO33131.1 - 5 6.5 5.6 9.7 5.6 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) THOC7 PF05615.8 ETO33131.1 - 6.7 6.9 12.9 1.5 9.1 3.2 2.8 1 1 2 3 3 3 0 Tho complex subunit 7 RNA_pol_Rpb8 PF03870.10 ETO33132.1 - 2.5e-41 141.0 0.5 2.8e-41 140.9 0.3 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 WD40 PF00400.27 ETO33135.1 - 1.9e-15 56.0 4.8 8e-11 41.3 0.8 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO33135.1 - 0.00017 19.8 0.2 0.00027 19.1 0.1 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 zf-C3HC4_2 PF13923.1 ETO33135.1 - 0.0056 16.6 2.2 0.036 14.1 1.5 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Yopt PF09467.5 ETO33135.1 - 0.044 13.6 0.9 0.38 10.6 0.2 2.5 2 0 0 2 2 2 0 Hypothetical protein Yopt ADIP PF11559.3 ETO33136.1 - 0.0088 15.9 1.3 0.0094 15.8 0.9 1.0 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF4570 PF15134.1 ETO33136.1 - 0.92 9.3 3.7 3.1 7.6 2.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4570) CPSF_A PF03178.10 ETO33137.1 - 1.9e-16 60.0 0.0 8.2e-16 57.9 0.0 1.8 1 1 0 1 1 1 1 CPSF A subunit region YobH PF13996.1 ETO33138.1 - 0.072 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 YobH-like protein MMS1_N PF10433.4 ETO33139.1 - 2.3e-15 55.7 0.3 3.9e-15 54.9 0.2 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CENP-B_dimeris PF09026.5 ETO33139.1 - 0.44 10.8 4.1 1.4 9.1 2.8 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.1 ETO33139.1 - 4.9 6.8 9.2 0.38 10.4 2.6 1.9 2 0 0 2 2 2 0 FAM176 family WD40 PF00400.27 ETO33142.1 - 5.3e-34 114.8 4.2 2.1e-10 40.0 0.0 4.7 4 1 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO33142.1 - 3.1e-05 22.3 0.1 0.054 11.6 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO33142.1 - 0.00018 21.2 0.0 0.0024 17.6 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 ETO33142.1 - 0.02 13.6 1.3 0.15 10.7 0.9 2.3 1 1 0 1 1 1 0 Nup133 N terminal like DUF1258 PF06869.7 ETO33142.1 - 0.047 12.7 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) PQQ_2 PF13360.1 ETO33142.1 - 0.075 12.4 0.2 0.56 9.6 0.1 2.0 1 1 0 2 2 2 0 PQQ-like domain WD40 PF00400.27 ETO33143.1 - 0.00029 20.5 0.1 0.00059 19.6 0.1 1.6 1 0 0 1 1 1 1 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO33143.1 - 0.00055 20.0 0.1 0.13 12.5 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.20 ETO33143.1 - 0.03 13.8 0.2 0.14 11.7 0.0 2.2 3 0 0 3 3 3 0 Kelch motif Kelch_3 PF13415.1 ETO33143.1 - 0.14 12.3 0.0 0.6 10.3 0.0 2.0 2 0 0 2 2 2 0 Galactose oxidase, central domain TrkA_C PF02080.16 ETO33143.1 - 0.16 11.6 0.0 0.45 10.1 0.0 1.8 2 0 0 2 2 2 0 TrkA-C domain DUF2330 PF10092.4 ETO33144.1 - 0.083 11.7 0.4 0.09 11.6 0.3 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2330) S4 PF01479.20 ETO33145.1 - 0.12 11.8 2.3 3.1 7.3 0.1 2.4 2 0 0 2 2 2 0 S4 domain Reo_sigmaC PF04582.7 ETO33145.1 - 0.26 10.4 5.5 0.9 8.6 1.3 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF4179 PF13786.1 ETO33147.1 - 0.086 13.0 0.9 3.7 7.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) G-alpha PF00503.15 ETO33148.1 - 3.2e-39 134.7 5.7 3.5e-39 134.5 4.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit RasGEF_N_2 PF14663.1 ETO33148.1 - 0.028 14.3 0.1 0.063 13.2 0.0 1.6 1 1 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Glyco_hydro_53 PF07745.8 ETO33148.1 - 0.036 12.8 0.5 0.043 12.5 0.3 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 Pik1 PF11522.3 ETO33148.1 - 0.11 12.2 0.1 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 Yeast phosphatidylinositol-4-OH kinase Pik1 Mannosyl_trans3 PF11051.3 ETO33148.1 - 0.13 11.5 1.1 0.16 11.3 0.7 1.2 1 1 0 1 1 1 0 Mannosyltransferase putative WD40 PF00400.27 ETO33149.1 - 3.4e-65 213.7 11.4 5.1e-14 51.5 0.1 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO33149.1 - 3e-12 45.4 3.3 0.0024 16.1 0.1 4.6 1 1 4 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO33149.1 - 1.4e-11 44.4 1.5 7.8e-06 25.7 0.3 2.8 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 ETO33149.1 - 8.8e-08 31.3 6.6 0.11 11.2 0.0 4.5 1 1 2 4 4 4 4 Nup133 N terminal like PQQ_2 PF13360.1 ETO33149.1 - 3.3e-07 30.0 0.2 2.3e-05 23.9 0.1 2.3 1 1 0 1 1 1 1 PQQ-like domain DPPIV_N PF00930.16 ETO33149.1 - 7.8e-06 24.7 0.1 0.55 8.7 0.0 3.7 1 1 2 4 4 4 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region Cytochrom_D1 PF02239.11 ETO33149.1 - 6.3e-05 21.4 0.2 0.0013 17.0 0.0 2.1 1 1 1 2 2 2 1 Cytochrome D1 heme domain PD40 PF07676.7 ETO33149.1 - 7.4e-05 22.3 8.9 0.42 10.3 0.1 5.0 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Hira PF07569.6 ETO33149.1 - 0.0028 16.8 0.3 2.5 7.2 0.0 3.7 2 1 0 3 3 3 1 TUP1-like enhancer of split Nbas_N PF15492.1 ETO33149.1 - 0.0038 16.3 1.5 8.3 5.4 0.1 3.6 1 1 3 4 4 4 1 Neuroblastoma-amplified sequence, N terminal DUF1797 PF08796.5 ETO33149.1 - 0.023 14.5 0.0 1.4 8.8 0.0 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1797) DUF1258 PF06869.7 ETO33149.1 - 0.055 12.5 0.2 5.3 6.0 0.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1258) Proteasome_A_N PF10584.4 ETO33149.1 - 0.12 11.7 11.2 9.5 5.6 0.0 5.0 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 ETO33150.1 - 1.5e-21 75.4 4.0 1.4e-10 40.6 0.0 3.6 4 0 0 4 4 4 3 WD domain, G-beta repeat Spc24 PF08286.6 ETO33150.1 - 0.0023 17.6 0.9 0.0043 16.7 0.6 1.5 1 0 0 1 1 1 1 Spc24 subunit of Ndc80 Nup160 PF11715.3 ETO33150.1 - 0.0082 14.3 0.7 0.33 9.0 0.1 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF1220 PF06758.8 ETO33150.1 - 0.037 13.8 0.8 0.66 9.8 0.0 2.8 2 2 0 2 2 2 0 Repeat of unknown function (DUF1220) RED_C PF07807.6 ETO33150.1 - 0.047 13.8 4.8 1.9 8.7 0.0 3.1 3 0 0 3 3 3 0 RED-like protein C-terminal region NEMO PF11577.3 ETO33150.1 - 0.64 9.8 7.3 0.14 11.9 2.6 1.7 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO TetM_leader PF08076.6 ETO33150.1 - 4.5 6.8 7.8 1.6 8.3 0.6 2.4 2 0 0 2 2 2 0 Tetracycline resistance determinant leader peptide WD40 PF00400.27 ETO33151.1 - 9.1e-72 234.5 16.5 3.4e-12 45.7 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO33151.1 - 7.7e-08 30.9 6.1 0.0033 15.6 0.3 4.7 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO33151.1 - 2.3e-05 23.3 9.9 0.16 10.6 0.2 4.3 1 1 2 3 3 3 3 Nup133 N terminal like PD40 PF07676.7 ETO33151.1 - 2.7e-05 23.7 4.2 2 8.1 0.1 4.6 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO33151.1 - 0.0006 19.3 0.3 0.05 13.0 0.1 2.3 1 1 1 2 2 2 2 PQQ-like domain Resistin PF06954.6 ETO33151.1 - 0.013 15.7 1.0 31 4.9 0.0 3.9 4 1 0 4 4 4 0 Resistin Ubiquitin_3 PF14836.1 ETO33151.1 - 0.016 14.8 0.0 5 6.8 0.0 3.3 2 1 1 3 3 3 0 Ubiquitin-like domain Cytochrom_D1 PF02239.11 ETO33151.1 - 0.027 12.7 0.2 2.3 6.3 0.0 2.8 1 1 2 3 3 3 0 Cytochrome D1 heme domain DUF1652 PF07865.6 ETO33151.1 - 0.083 12.4 0.0 7.3 6.2 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1652) Proteasome_A_N PF10584.4 ETO33151.1 - 0.086 12.1 0.6 38 3.7 0.0 3.9 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature RicinB_lectin_2 PF14200.1 ETO33151.1 - 0.1 12.9 0.1 8.2 6.8 0.0 3.1 2 2 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like WD40 PF00400.27 ETO33152.1 - 6.4e-69 225.5 23.8 4e-12 45.5 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO33152.1 - 6.3e-08 31.2 6.0 0.039 12.0 0.3 4.3 2 1 2 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO33152.1 - 8.2e-08 32.1 1.6 0.00069 19.3 0.0 3.4 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO33152.1 - 2e-07 30.5 5.7 0.034 13.8 0.1 5.2 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO33152.1 - 0.00011 21.0 15.1 0.51 9.0 0.3 5.0 1 1 2 3 3 3 2 Nup133 N terminal like Coatomer_WDAD PF04053.9 ETO33152.1 - 0.0016 17.2 4.0 1.5 7.5 0.2 3.1 1 1 2 3 3 3 3 Coatomer WD associated region Resistin PF06954.6 ETO33152.1 - 0.0067 16.6 0.2 16 5.8 0.0 3.7 1 1 2 3 3 3 1 Resistin DUF3601 PF12208.3 ETO33152.1 - 0.045 13.6 0.1 1 9.3 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF3601) WD40 PF00400.27 ETO33153.1 - 3.1e-36 121.9 14.0 2.5e-09 36.6 0.1 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO33153.1 - 0.0008 17.6 1.6 0.14 10.2 0.1 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO33154.1 - 4.7e-09 36.0 4.0 0.00021 21.2 0.0 4.4 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO33154.1 - 1.4e-06 27.8 4.2 0.045 13.5 0.0 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 ETO33154.1 - 3e-06 27.0 0.5 0.024 14.5 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 ETO33154.1 - 2.4e-05 23.7 4.2 0.0042 16.5 0.0 3.2 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO33154.1 - 0.0011 18.7 0.2 0.058 13.1 0.0 2.9 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO33154.1 - 0.002 18.2 0.0 0.075 13.2 0.0 2.8 2 0 0 2 2 2 1 Galactose oxidase, central domain OmdA PF13376.1 ETO33155.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated WD40 PF00400.27 ETO33157.1 - 2.3e-13 49.4 3.5 1.9e-08 33.8 0.7 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO33157.1 - 6.7e-06 24.5 0.1 9.6e-06 24.0 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO33157.1 - 0.00038 20.7 2.2 0.00038 20.7 1.5 2.4 2 1 0 2 2 2 1 TRAF-type zinc finger IncA PF04156.9 ETO33157.1 - 1.3 8.5 10.7 2.8 7.4 7.4 1.6 1 0 0 1 1 1 0 IncA protein zf-C3HC4_2 PF13923.1 ETO33157.1 - 7.8 6.6 13.0 0.18 11.8 1.7 3.2 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) RNase_H PF00075.19 ETO33158.1 - 7.7e-18 65.1 0.0 1.3e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 ETO33158.1 - 0.00063 20.0 0.2 0.0017 18.6 0.1 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_3 PF13456.1 ETO33158.1 - 0.0014 18.3 0.0 0.0039 16.9 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase-like His_Phos_1 PF00300.17 ETO33160.1 - 9e-14 51.8 0.0 1.6e-13 51.0 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Med6 PF04934.9 ETO33160.1 - 0.056 12.9 0.1 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 MED6 mediator sub complex component FliD_N PF02465.13 ETO33161.1 - 0.00094 19.5 11.9 0.0037 17.5 8.3 2.0 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 N-terminus zf-CCHC_4 PF14392.1 ETO33161.1 - 2 8.1 16.8 0.73 9.5 1.1 3.4 2 1 1 3 3 3 0 Zinc knuckle RVT_1 PF00078.22 ETO33162.1 - 8.2e-35 120.1 0.1 1.6e-34 119.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1191 PF06697.7 ETO33165.1 - 0.041 12.6 0.0 0.06 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Laminin_G_3 PF13385.1 ETO33165.1 - 0.042 14.0 0.3 0.11 12.6 0.2 1.8 1 1 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily DUF2985 PF11204.3 ETO33165.1 - 0.61 9.8 3.4 0.52 10.0 0.2 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2985) LRR_6 PF13516.1 ETO33167.1 - 8.8e-13 46.8 0.1 0.00063 19.5 0.0 5.1 4 0 0 4 4 4 2 Leucine Rich repeat adh_short PF00106.20 ETO33167.1 - 0.00019 21.3 0.0 0.00065 19.6 0.0 2.0 1 0 0 1 1 1 1 short chain dehydrogenase Tuberculin PF12198.3 ETO33169.1 - 0.79 9.6 3.7 1.4 8.8 2.6 1.4 1 0 0 1 1 1 0 Theoretical tuberculin protein CHAT PF12770.2 ETO33170.1 - 1.5e-06 27.5 0.9 6.2e-06 25.5 0.6 2.1 1 1 0 1 1 1 1 CHAT domain NACHT PF05729.7 ETO33170.1 - 0.0005 19.7 0.0 0.0049 16.5 0.0 2.4 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.17 ETO33170.1 - 0.00091 18.1 3.7 0.017 13.9 0.0 3.5 3 1 1 4 4 4 1 NB-ARC domain AAA PF00004.24 ETO33170.1 - 0.0063 16.7 1.8 0.08 13.1 0.0 3.4 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETO33170.1 - 0.057 13.5 0.0 1.7 8.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 ETO33170.1 - 3.5 7.9 0.0 3.5 7.9 0.0 2.8 2 0 0 2 2 2 0 ABC transporter AAA_17 PF13207.1 ETO33170.1 - 5 7.9 6.2 10 6.9 0.0 3.6 4 1 0 4 4 4 0 AAA domain NDT80_PhoG PF05224.7 ETO33171.1 - 0.033 14.1 4.5 0.04 13.9 3.1 1.1 1 0 0 1 1 1 0 NDT80 / PhoG like DNA-binding family SID-1_RNA_chan PF13965.1 ETO33171.1 - 0.073 11.2 2.8 0.08 11.0 1.9 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 UPF0270 PF06794.7 ETO33171.1 - 0.26 11.0 2.8 1.6 8.5 0.1 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0270) Vmethyltransf_C PF08456.5 ETO33172.1 - 0.0024 17.3 0.4 0.006 16.0 0.3 1.6 1 0 0 1 1 1 1 Viral methyltransferase C-terminal DUF4304 PF14137.1 ETO33172.1 - 1.5 8.9 6.6 2.4 8.3 1.4 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4304) CENP-K PF11802.3 ETO33172.1 - 6.6 5.8 12.7 5 6.2 4.6 2.2 1 1 1 2 2 2 0 Centromere-associated protein K RGS PF00615.14 ETO33175.1 - 0.022 14.8 0.1 0.054 13.6 0.1 1.7 1 0 0 1 1 1 0 Regulator of G protein signaling domain PH PF00169.24 ETO33178.1 - 0.014 15.6 1.7 0.78 9.9 0.3 2.7 2 0 0 2 2 2 0 PH domain MSC PF09402.5 ETO33179.1 - 1.8 7.1 8.5 0.56 8.8 0.1 2.7 2 1 1 3 3 3 0 Man1-Src1p-C-terminal domain SelR PF01641.13 ETO33181.1 - 1.2e-34 118.6 0.0 1.6e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 SelR domain Spermine_synth PF01564.12 ETO33182.1 - 1.1e-51 175.1 0.0 1.5e-51 174.6 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_30 PF05430.6 ETO33182.1 - 0.0027 17.3 0.0 0.006 16.2 0.0 1.6 1 0 0 1 1 1 1 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_26 PF13659.1 ETO33182.1 - 0.0063 16.5 0.0 0.013 15.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO33182.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain KIX PF02172.11 ETO33182.1 - 0.03 14.3 0.1 5.9 7.0 0.0 2.6 2 0 0 2 2 2 0 KIX domain HCaRG PF07258.9 ETO33184.1 - 4.9e-16 58.7 3.8 1.9e-14 53.5 2.6 2.6 1 1 0 1 1 1 1 HCaRG protein TPR_2 PF07719.12 ETO33185.1 - 8.7e-23 78.3 20.6 8e-05 22.2 0.1 8.3 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_11 PF13414.1 ETO33185.1 - 3.2e-21 74.7 20.9 1.3e-06 27.9 1.4 7.0 3 3 2 6 6 6 6 TPR repeat TPR_19 PF14559.1 ETO33185.1 - 4.4e-21 74.9 11.9 1.7e-06 28.2 0.4 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 ETO33185.1 - 1e-18 66.0 1.9 0.014 15.9 0.0 7.7 5 2 3 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO33185.1 - 1.7e-17 63.5 0.5 1.3e-05 25.6 0.0 6.4 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO33185.1 - 1.7e-16 59.0 20.4 0.0006 19.3 0.0 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 ETO33185.1 - 1.6e-14 53.5 19.4 8.2e-06 25.6 0.8 7.5 4 3 4 9 9 9 5 Tetratricopeptide repeat TPR_17 PF13431.1 ETO33185.1 - 1.4e-13 49.8 13.3 0.24 11.7 0.0 8.2 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_7 PF13176.1 ETO33185.1 - 8.3e-12 43.9 2.9 0.0089 15.7 0.0 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO33185.1 - 1.3e-09 37.1 20.0 0.013 15.1 0.1 8.5 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.1 ETO33185.1 - 2.3e-08 33.9 9.9 1.6 9.3 0.0 7.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO33185.1 - 3.2e-08 33.2 2.4 0.93 9.5 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 ETO33185.1 - 1.4e-05 25.1 21.4 0.0091 16.1 2.8 6.3 4 3 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 ETO33185.1 - 0.018 15.3 0.2 0.81 10.2 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat NAAA-beta PF15508.1 ETO33185.1 - 0.072 13.4 2.7 0.99 9.7 0.5 3.0 2 1 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Fis1_TPR_C PF14853.1 ETO33185.1 - 0.23 11.3 6.5 4.9 7.1 0.0 4.4 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat Aldo_ket_red PF00248.16 ETO33186.1 - 0.0006 18.7 0.0 0.00069 18.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_L15e PF00827.12 ETO33188.1 - 3.4e-57 193.0 11.6 3.3e-32 111.5 4.4 2.2 1 1 1 2 2 2 2 Ribosomal L15 Oxidored_molyb PF00174.14 ETO33189.1 - 1.6e-37 128.5 0.0 3e-37 127.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 ETO33189.1 - 2e-22 79.2 0.0 4.1e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.23 ETO33189.1 - 6.8e-11 41.8 0.3 1.1e-07 31.4 0.0 3.0 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain BNR PF02012.15 ETO33189.1 - 0.064 13.1 0.7 0.7 9.9 0.0 3.2 3 0 0 3 3 3 0 BNR/Asp-box repeat p25-alpha PF05517.7 ETO33190.1 - 0.014 15.6 5.4 0.015 15.5 3.7 1.0 1 0 0 1 1 1 0 p25-alpha FAST_2 PF08368.7 ETO33190.1 - 0.11 12.8 1.0 0.12 12.7 0.7 1.2 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 2 GDPD PF03009.12 ETO33190.1 - 0.36 10.2 2.9 0.37 10.2 2.0 1.0 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Med28 PF11594.3 ETO33190.1 - 0.46 10.7 8.0 0.55 10.4 5.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 28 Ribosomal_L6e PF01159.14 ETO33190.1 - 0.65 10.2 7.8 0.7 10.1 5.4 1.1 1 0 0 1 1 1 0 Ribosomal protein L6e DUF2532 PF10811.3 ETO33190.1 - 0.9 9.3 9.5 1.2 8.8 6.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2532) DUF4061 PF13270.1 ETO33190.1 - 1.2 9.3 6.7 1.3 9.1 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) Atg8 PF02991.11 ETO33191.1 - 0.017 15.1 0.0 4.5 7.2 0.0 2.4 2 0 0 2 2 2 0 Autophagy protein Atg8 ubiquitin like RRM_1 PF00076.17 ETO33192.1 - 1.7e-11 43.6 0.1 2.4e-11 43.0 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO33192.1 - 7.8e-09 35.3 0.0 1.1e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO33192.1 - 8.5e-05 22.3 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 ETO33192.1 - 0.002 17.9 0.0 0.0027 17.5 0.0 1.2 1 0 0 1 1 1 1 RNA binding motif Surfac_D-trimer PF09006.6 ETO33192.1 - 0.03 14.0 2.4 4.3 7.1 0.0 2.2 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation RNA_bind PF08675.6 ETO33192.1 - 0.097 12.6 0.0 0.2 11.6 0.0 1.6 2 0 0 2 2 2 0 RNA binding domain WD40 PF00400.27 ETO33193.1 - 1.2e-63 208.8 22.8 9.4e-11 41.1 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO33193.1 - 7.9e-05 20.9 0.5 0.31 9.1 0.0 2.8 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 ETO33193.1 - 0.005 15.9 0.7 5.6 5.9 0.1 3.4 2 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PQQ PF01011.16 ETO33193.1 - 0.063 12.8 0.0 1.6 8.3 0.0 3.2 4 0 0 4 4 4 0 PQQ enzyme repeat DUF2684 PF10885.3 ETO33193.1 - 0.17 11.7 2.0 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2684) zf-C3HC4_3 PF13920.1 ETO33194.1 - 7.9e-09 35.0 15.5 2.8e-08 33.2 10.7 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SAM_2 PF07647.12 ETO33194.1 - 0.00042 20.1 0.8 0.0023 17.7 0.1 2.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) zf-C3HC4_2 PF13923.1 ETO33194.1 - 0.0023 17.9 19.0 0.0023 17.9 13.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAM_1 PF00536.25 ETO33194.1 - 0.023 14.8 0.1 0.023 14.8 0.1 2.6 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Nup54 PF13874.1 ETO33194.1 - 0.049 13.2 8.6 0.031 13.9 1.0 3.3 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 NPV_P10 PF05531.7 ETO33194.1 - 0.92 9.7 6.7 0.5 10.6 0.8 3.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein zf-C3HC4 PF00097.20 ETO33194.1 - 1.3 8.7 18.1 4.9 6.8 12.5 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2968 PF11180.3 ETO33194.1 - 1.9 7.8 9.6 0.031 13.6 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) zf-TRAF PF02176.13 ETO33195.1 - 0.0013 19.0 1.5 0.0013 19.0 1.0 2.1 2 0 0 2 2 2 1 TRAF-type zinc finger Cas_Cas1 PF01867.11 ETO33195.1 - 0.3 10.1 6.5 0.69 8.9 4.5 1.7 1 1 0 1 1 1 0 CRISPR associated protein Cas1 FERM_M PF00373.13 ETO33195.1 - 0.49 10.5 3.4 1 9.5 2.2 1.7 1 1 0 1 1 1 0 FERM central domain DUF4304 PF14137.1 ETO33195.1 - 0.78 9.8 5.5 2.2 8.4 3.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4304) WD40 PF00400.27 ETO33196.1 - 6.3e-23 79.7 6.2 4.7e-11 42.1 0.7 3.6 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO33196.1 - 0.00074 17.7 1.4 0.95 7.5 0.1 2.8 1 1 2 3 3 3 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO33196.1 - 0.086 12.6 0.9 0.28 10.9 0.2 2.1 1 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.27 ETO33197.1 - 2.2e-17 62.1 6.0 0.00068 19.4 0.1 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.6 ETO33197.1 - 1.9e-08 34.2 0.3 0.0019 17.9 0.0 2.9 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 ETO33197.1 - 1.7e-06 27.7 0.0 1.4e-05 24.6 0.0 2.3 1 1 0 2 2 2 1 PQQ-like domain Coatomer_WDAD PF04053.9 ETO33197.1 - 5e-06 25.5 0.4 0.0027 16.5 0.1 2.7 1 1 1 2 2 2 2 Coatomer WD associated region PD40 PF07676.7 ETO33197.1 - 1.4e-05 24.6 0.4 1 9.0 0.0 5.4 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 ETO33197.1 - 0.00026 19.6 0.5 5.1 5.5 0.0 4.1 2 1 2 4 4 4 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region PQQ PF01011.16 ETO33197.1 - 0.0036 16.7 0.0 0.26 10.8 0.0 3.2 2 0 0 2 2 2 1 PQQ enzyme repeat Kelch_6 PF13964.1 ETO33197.1 - 0.018 15.2 3.9 1.4 9.2 0.2 4.7 5 0 0 5 5 5 0 Kelch motif Chibby PF14645.1 ETO33197.1 - 0.019 14.8 5.1 0.025 14.4 2.6 1.9 1 1 1 2 2 2 0 Chibby family Proteasome_A_N PF10584.4 ETO33197.1 - 0.088 12.1 0.6 18 4.7 0.0 3.2 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Z1 PF10593.4 ETO33199.1 - 0.06 12.5 0.3 0.11 11.7 0.2 1.4 1 0 0 1 1 1 0 Z1 domain MIP-T3 PF10243.4 ETO33200.1 - 0.11 10.9 13.6 0.17 10.3 9.5 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1777 PF08648.7 ETO33200.1 - 1.2 8.8 56.7 8.6 6.0 39.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) zf-C3HC4_2 PF13923.1 ETO33201.1 - 0.017 15.1 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 ETO33201.1 - 0.026 14.2 0.1 0.077 12.7 0.0 1.9 2 0 0 2 2 2 0 RING-type zinc-finger Paramyxo_ncap PF00973.14 ETO33201.1 - 0.92 8.1 9.3 1.2 7.7 6.4 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF365 PF04033.7 ETO33202.1 - 0.013 15.5 0.4 7.4 6.6 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF365) DUF912 PF06024.7 ETO33203.1 - 0.0044 17.0 7.3 0.42 10.7 0.4 3.0 3 0 0 3 3 3 2 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4522 PF15022.1 ETO33203.1 - 0.066 12.9 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4522) TRAP_beta PF05753.9 ETO33203.1 - 0.07 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein beta (TRAPB) Ank PF00023.25 ETO33204.1 - 1.2e-20 72.2 0.1 3.7e-08 32.7 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 ETO33204.1 - 2.6e-17 62.9 0.1 1e-12 48.1 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO33204.1 - 2.8e-17 61.0 0.1 2.2e-06 27.3 0.1 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 ETO33204.1 - 7.5e-15 54.9 0.2 1.8e-05 25.0 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO33204.1 - 3.6e-10 39.7 0.3 2.9e-05 24.1 0.1 5.8 5 1 1 6 6 6 3 Ankyrin repeats (many copies) TFIIA PF03153.8 ETO33204.1 - 1.8 8.3 57.5 0.14 12.0 32.0 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.27 ETO33205.1 - 0.0001 22.0 1.1 0.00091 19.0 1.1 2.2 2 1 0 2 2 2 1 WD domain, G-beta repeat N-glycanase_N PF09112.5 ETO33205.1 - 0.015 14.6 0.1 0.024 14.0 0.1 1.4 1 0 0 1 1 1 0 Peptide-N-glycosidase F, N terminal SelP_N PF04592.9 ETO33206.1 - 2.5 7.4 19.8 0.067 12.5 9.0 1.8 2 0 0 2 2 2 0 Selenoprotein P, N terminal region DUF1777 PF08648.7 ETO33206.1 - 4.8 6.8 19.3 0.42 10.3 9.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) BTB PF00651.26 ETO33208.1 - 1.7e-08 34.4 0.6 4.4e-08 33.0 0.2 1.8 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.10 ETO33208.1 - 7.1e-07 29.0 0.7 7.1e-07 29.0 0.5 3.3 4 0 0 4 4 4 1 BTB And C-terminal Kelch Tol_Tol_Ttg2 PF05494.7 ETO33208.1 - 0.033 13.7 0.1 0.082 12.4 0.1 1.6 1 0 0 1 1 1 0 Toluene tolerance, Ttg2 Mad3_BUB1_I PF08311.7 ETO33208.1 - 0.05 13.3 1.6 1.6 8.5 0.1 2.5 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 CRPV_capsid PF08762.5 ETO33210.1 - 0.13 11.6 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 CRPV capsid protein like Dpy-30 PF05186.8 ETO33211.1 - 8.8e-10 37.9 0.0 1.8e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Dpy-30 motif YqhG PF11079.3 ETO33211.1 - 0.0014 17.5 2.4 0.0022 16.8 1.7 1.3 1 0 0 1 1 1 1 Bacterial protein YqhG of unknown function FERM_M PF00373.13 ETO33211.1 - 0.14 12.3 5.4 0.097 12.8 2.6 1.6 2 0 0 2 2 2 0 FERM central domain DUF4606 PF15379.1 ETO33212.1 - 0.067 13.2 0.2 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) DUF1754 PF08555.5 ETO33213.1 - 0.39 11.3 5.7 0.56 10.8 4.0 1.3 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Pkinase PF00069.20 ETO33214.1 - 6.2e-29 100.9 11.3 1.2e-25 90.1 7.8 3.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO33214.1 - 3.3e-20 72.2 1.3 5.1e-14 51.9 0.0 3.3 2 1 1 3 3 3 3 Protein tyrosine kinase Kdo PF06293.9 ETO33214.1 - 0.00016 20.8 0.0 0.00053 19.1 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETO33214.1 - 0.006 15.5 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pex14_N PF04695.8 ETO33214.1 - 0.074 13.1 0.2 0.074 13.1 0.2 4.1 3 1 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region APH PF01636.18 ETO33214.1 - 0.081 12.6 0.0 0.17 11.5 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Methyltransf_12 PF08242.7 ETO33214.1 - 0.65 10.4 15.8 0.15 12.5 0.6 2.6 1 1 1 2 2 2 0 Methyltransferase domain Kelch_6 PF13964.1 ETO33215.1 - 2.8e-06 27.2 4.9 0.11 12.7 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO33215.1 - 5.2e-05 22.7 2.6 0.0061 16.0 0.1 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 ETO33215.1 - 0.00019 21.0 2.9 0.036 13.8 0.0 3.5 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO33215.1 - 0.054 13.2 1.6 1.6 8.5 0.0 2.8 2 1 1 3 3 3 0 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO33215.1 - 0.094 12.7 5.7 6.6 6.7 0.6 3.6 4 0 0 4 4 4 0 Kelch motif D-aminoacyl_C PF07908.7 ETO33215.1 - 0.18 11.1 0.0 0.37 10.1 0.0 1.4 1 0 0 1 1 1 0 D-aminoacylase, C-terminal region TRAPPC-Trs85 PF12739.2 ETO33218.1 - 0.021 13.4 0.0 0.027 13.1 0.0 1.1 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit UCH PF00443.24 ETO33219.1 - 2.5e-67 226.8 14.0 2.5e-67 226.8 9.7 3.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO33219.1 - 4.2e-09 36.2 0.1 4.2e-09 36.2 0.1 4.3 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Tudor-knot PF11717.3 ETO33219.1 - 0.014 15.0 0.1 0.047 13.3 0.1 1.9 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Aldedh PF00171.17 ETO33220.1 - 8.9e-37 126.4 0.3 6.8e-21 74.1 0.0 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Cellulase PF00150.13 ETO33220.1 - 0.024 13.8 0.0 0.047 12.8 0.0 1.4 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Viral_protease PF08715.5 ETO33220.1 - 0.047 12.7 1.0 0.071 12.1 0.7 1.2 1 0 0 1 1 1 0 Papain like viral protease LELP1 PF15042.1 ETO33221.1 - 0.068 13.3 0.2 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 Syndecan PF01034.15 ETO33222.1 - 0.00089 18.8 0.2 0.0017 17.9 0.1 1.4 1 0 0 1 1 1 1 Syndecan domain SAM_2 PF07647.12 ETO33222.1 - 0.0027 17.5 0.1 0.0053 16.5 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) FixQ PF05545.6 ETO33222.1 - 0.012 15.2 0.1 0.022 14.4 0.1 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ TMEM154 PF15102.1 ETO33222.1 - 0.014 15.1 0.4 0.028 14.1 0.3 1.6 1 0 0 1 1 1 0 TMEM154 protein family Sigma_reg_N PF13800.1 ETO33222.1 - 0.09 12.8 1.4 0.092 12.7 0.0 1.8 2 0 0 2 2 2 0 Sigma factor regulator N-terminal SAM_1 PF00536.25 ETO33222.1 - 0.097 12.8 0.1 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Pkinase PF00069.20 ETO33223.1 - 4.2e-41 140.8 0.1 1.4e-26 93.1 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO33223.1 - 1.7e-22 79.7 0.0 1.1e-18 67.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 ETO33223.1 - 0.00089 18.2 0.0 0.32 9.9 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 ETO33223.1 - 0.0025 16.9 0.3 0.0054 15.8 0.0 1.5 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO33223.1 - 0.0089 15.7 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 ETO33223.1 - 0.029 13.6 0.2 0.16 11.3 0.0 1.9 1 1 1 2 2 2 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 ETO33223.1 - 0.034 13.4 0.0 0.063 12.6 0.0 1.5 1 0 0 1 1 1 0 RIO1 family YukC PF10140.4 ETO33223.1 - 0.034 12.7 0.0 0.14 10.7 0.0 2.0 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC PCAF_N PF06466.6 ETO33224.1 - 0.0064 15.8 1.2 0.0085 15.4 0.8 1.1 1 0 0 1 1 1 1 PCAF (P300/CBP-associated factor) N-terminal domain EF-hand_7 PF13499.1 ETO33225.1 - 5.4e-08 32.8 4.5 0.0024 17.9 0.0 4.0 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.27 ETO33225.1 - 2.2e-07 29.6 9.6 0.00097 18.2 0.2 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 ETO33225.1 - 2.3e-07 30.1 2.3 0.013 15.2 0.1 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 ETO33225.1 - 3.1e-06 26.7 4.2 0.044 13.3 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 ETO33225.1 - 6.1e-06 25.3 15.4 0.00012 21.3 1.2 3.7 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.2 ETO33225.1 - 0.012 15.3 7.6 0.18 11.5 0.6 3.2 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand Tn7_Tnp_TnsA_C PF08721.6 ETO33225.1 - 0.26 11.3 3.7 0.97 9.4 0.5 3.2 2 2 1 3 3 3 0 TnsA endonuclease C terminal Ndc1_Nup PF09531.5 ETO33225.1 - 1.8 6.9 10.6 2.1 6.6 7.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Cwf_Cwc_15 PF04889.7 ETO33226.1 - 0.00069 19.4 11.0 0.00085 19.1 7.6 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Senescence_reg PF04520.8 ETO33226.1 - 0.0028 18.1 1.9 0.0034 17.8 1.3 1.2 1 0 0 1 1 1 1 Senescence regulator NARP1 PF12569.3 ETO33226.1 - 0.0035 16.1 6.5 0.0046 15.7 4.5 1.1 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 DUF1510 PF07423.6 ETO33226.1 - 0.0098 15.2 12.6 0.025 13.9 5.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) EF-hand_1 PF00036.27 ETO33226.1 - 0.0098 15.1 0.2 0.03 13.6 0.2 1.9 1 0 0 1 1 1 1 EF hand Vfa1 PF08432.5 ETO33226.1 - 0.015 15.3 10.7 0.021 14.8 7.4 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Strabismus PF06638.6 ETO33226.1 - 0.016 13.5 3.4 0.022 13.1 2.4 1.1 1 0 0 1 1 1 0 Strabismus protein Rib_recp_KP_reg PF05104.7 ETO33226.1 - 0.017 15.6 8.4 0.026 15.0 5.8 1.2 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region GAGA_bind PF06217.7 ETO33226.1 - 0.036 14.0 4.7 0.043 13.7 3.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family BSP_II PF05432.6 ETO33226.1 - 0.044 13.0 9.8 0.068 12.4 6.8 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) FAM176 PF14851.1 ETO33226.1 - 0.051 13.2 6.9 0.11 12.1 4.8 1.6 1 0 0 1 1 1 0 FAM176 family SID-1_RNA_chan PF13965.1 ETO33226.1 - 0.055 11.6 8.3 0.025 12.7 3.2 1.9 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 BTV_NS2 PF04514.7 ETO33226.1 - 0.078 11.8 10.8 0.1 11.4 7.5 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 SelP_N PF04592.9 ETO33226.1 - 0.08 12.3 6.1 0.12 11.7 4.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region GD_AH_C PF04295.8 ETO33226.1 - 0.095 11.3 0.1 0.14 10.7 0.1 1.2 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus Asp-B-Hydro_N PF05279.6 ETO33226.1 - 0.12 12.1 11.5 0.15 11.9 7.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region TFIIF_alpha PF05793.7 ETO33226.1 - 0.15 10.4 14.9 0.19 10.0 10.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MRP-S26 PF14943.1 ETO33226.1 - 0.16 11.5 15.1 0.31 10.5 10.5 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF1168 PF06658.7 ETO33226.1 - 0.16 11.5 19.3 0.26 10.7 13.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) DUF688 PF05097.7 ETO33226.1 - 0.16 10.8 8.2 0.22 10.4 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) Pox_Ag35 PF03286.9 ETO33226.1 - 0.25 10.8 13.1 0.39 10.2 9.0 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Myc_N PF01056.13 ETO33226.1 - 0.3 10.2 9.0 0.42 9.7 6.3 1.2 1 0 0 1 1 1 0 Myc amino-terminal region FYDLN_acid PF09538.5 ETO33226.1 - 0.3 11.6 12.2 0.49 11.0 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF2457 PF10446.4 ETO33226.1 - 0.38 9.4 16.8 0.54 8.9 11.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FLO_LFY PF01698.11 ETO33226.1 - 0.45 9.3 11.2 0.63 8.8 7.7 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Peptidase_S49_N PF08496.5 ETO33226.1 - 0.51 10.1 14.5 3.5 7.4 0.1 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal CDC45 PF02724.9 ETO33226.1 - 0.52 8.2 10.7 0.82 7.6 7.4 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF3537 PF12056.3 ETO33226.1 - 0.78 8.3 4.3 1.2 7.7 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) RNA_pol_3_Rpc31 PF11705.3 ETO33226.1 - 0.92 9.4 18.9 1.4 8.7 13.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Zip PF02535.17 ETO33226.1 - 0.98 8.3 3.9 1.4 7.8 2.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Astro_capsid PF03115.9 ETO33226.1 - 1.4 7.0 6.4 1.8 6.6 4.4 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Prothymosin PF03247.9 ETO33226.1 - 1.4 9.0 25.0 0.12 12.5 12.4 2.0 2 0 0 2 2 2 0 Prothymosin/parathymosin family PBP_sp32 PF07222.7 ETO33226.1 - 2.5 7.2 14.2 3.9 6.5 9.8 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 LAM_C PF12544.3 ETO33226.1 - 3.8 7.5 7.3 6.5 6.8 5.1 1.4 1 0 0 1 1 1 0 Lysine-2,3-aminomutase DUF1312 PF07009.6 ETO33226.1 - 3.8 7.3 10.2 0.079 12.7 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1312) DUF262 PF03235.9 ETO33226.1 - 6.5 6.6 11.7 8.3 6.3 8.1 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF262 OAD_gamma PF04277.8 ETO33226.1 - 7.7 6.9 6.3 4.7 7.6 1.1 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Sporozoite_P67 PF05642.6 ETO33226.1 - 8.4 4.1 9.6 11 3.7 6.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Spore_III_AB PF09548.5 ETO33227.1 - 0.12 12.0 2.1 0.2 11.4 1.5 1.4 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Herpes_LMP1 PF05297.6 ETO33227.1 - 4.6 6.0 6.2 5.4 5.8 4.3 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF1598 PF07643.6 ETO33228.1 - 0.12 12.4 1.4 0.22 11.5 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1598) ORF6C PF10552.4 ETO33228.1 - 1.5 8.5 7.3 9.6 5.9 0.4 2.5 1 1 1 2 2 2 0 ORF6C domain GrpE PF01025.14 ETO33228.1 - 1.9 8.0 10.6 4 6.9 7.3 1.5 1 0 0 1 1 1 0 GrpE HEAT PF02985.17 ETO33229.1 - 5.2e-34 113.2 30.0 0.014 15.4 0.0 19.8 22 0 0 22 22 22 8 HEAT repeat HEAT_2 PF13646.1 ETO33229.1 - 1.6e-33 114.8 7.7 0.00021 21.5 0.1 15.0 8 5 8 16 16 16 6 HEAT repeats HEAT_EZ PF13513.1 ETO33229.1 - 2.7e-30 104.0 8.9 0.019 15.4 0.0 15.1 12 3 3 15 15 15 8 HEAT-like repeat CLASP_N PF12348.3 ETO33229.1 - 4.6e-18 65.4 6.2 0.0035 16.7 0.0 8.6 6 2 2 8 8 8 5 CLASP N terminal Vac14_Fab1_bd PF12755.2 ETO33229.1 - 1.1e-16 60.9 0.8 0.41 11.0 0.0 11.8 12 2 2 14 14 14 3 Vacuolar 14 Fab1-binding region Cohesin_HEAT PF12765.2 ETO33229.1 - 4.1e-05 23.4 3.2 4.1 7.4 0.0 5.9 4 1 0 4 4 4 2 HEAT repeat associated with sister chromatid cohesion Arm PF00514.18 ETO33229.1 - 0.00024 20.8 6.8 7.4 6.5 0.0 8.7 9 0 0 9 9 9 1 Armadillo/beta-catenin-like repeat MMS19_C PF12460.3 ETO33229.1 - 0.0077 15.0 0.0 0.0077 15.0 0.0 6.6 7 0 0 7 7 7 1 RNAPII transcription regulator C-terminal YrvL PF14184.1 ETO33229.1 - 0.13 12.0 0.2 0.85 9.4 0.0 2.5 2 0 0 2 2 2 0 Regulatory protein YrvL zf-TRAF PF02176.13 ETO33230.1 - 6.9e-06 26.3 2.5 6.9e-06 26.3 1.7 2.5 2 1 0 2 2 2 1 TRAF-type zinc finger Cys_knot PF00007.17 ETO33230.1 - 1 9.5 6.9 0.58 10.2 1.8 2.4 2 0 0 2 2 2 0 Cystine-knot domain zf-rbx1 PF12678.2 ETO33230.1 - 4.5 7.4 13.1 0.27 11.3 2.0 3.1 2 2 0 2 2 2 0 RING-H2 zinc finger Peptidase_C14 PF00656.17 ETO33231.1 - 4.6e-13 49.4 0.7 7.4e-13 48.7 0.5 1.3 1 0 0 1 1 1 1 Caspase domain UCH PF00443.24 ETO33231.1 - 0.013 14.6 1.6 0.028 13.5 1.0 1.6 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF3006 PF11213.3 ETO33231.1 - 0.031 14.0 0.1 8.8 6.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) WD40 PF00400.27 ETO33232.1 - 3.7e-164 527.4 50.9 1.1e-11 44.1 0.1 16.2 16 0 0 16 16 16 16 WD domain, G-beta repeat Pentapeptide_4 PF13599.1 ETO33232.1 - 2.9e-06 26.9 0.2 8.1e-06 25.5 0.2 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETO33232.1 - 1.9e-05 23.8 0.2 4.4e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Cytochrom_D1 PF02239.11 ETO33232.1 - 3.1e-05 22.4 12.3 0.022 13.0 0.2 5.4 3 2 2 6 6 6 2 Cytochrome D1 heme domain Pentapeptide_3 PF13576.1 ETO33232.1 - 0.00033 20.4 0.1 0.0013 18.6 0.1 2.1 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Resistin PF06954.6 ETO33232.1 - 0.00083 19.5 3.7 1.4 9.2 0.0 5.9 4 2 3 7 7 7 1 Resistin PD40 PF07676.7 ETO33232.1 - 0.0044 16.6 27.1 1 9.1 0.1 9.2 11 0 0 11 11 11 2 WD40-like Beta Propeller Repeat LAGLIDADG_3 PF14528.1 ETO33232.1 - 0.058 13.6 0.2 73 3.7 0.0 4.3 3 0 0 3 3 3 0 LAGLIDADG-like domain NACHT PF05729.7 ETO33233.1 - 5.8e-06 26.0 0.0 0.022 14.4 0.0 2.6 1 1 1 2 2 2 2 NACHT domain AAA_18 PF13238.1 ETO33233.1 - 0.00012 22.3 2.6 0.00063 20.0 0.0 3.6 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.1 ETO33233.1 - 0.0026 17.8 0.0 0.014 15.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 ETO33233.1 - 0.0035 17.6 0.0 0.022 15.0 0.0 2.3 2 0 0 2 2 2 1 ABC transporter DAP3 PF10236.4 ETO33233.1 - 0.0042 16.0 0.2 0.049 12.5 0.0 2.6 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 UPF0079 PF02367.12 ETO33233.1 - 0.0043 16.6 0.1 0.027 14.0 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 RelA_SpoT PF04607.12 ETO33233.1 - 0.0048 16.8 0.4 0.0048 16.8 0.3 2.9 3 0 0 3 3 3 1 Region found in RelA / SpoT proteins AAA_17 PF13207.1 ETO33233.1 - 0.0055 17.5 0.0 0.027 15.3 0.0 2.2 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 ETO33233.1 - 0.032 14.3 1.1 0.15 12.2 0.0 2.7 3 0 0 3 3 3 0 RNA helicase AAA_16 PF13191.1 ETO33233.1 - 0.04 13.8 0.1 0.14 12.1 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 ETO33233.1 - 0.16 11.8 0.0 0.42 10.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain TUDOR PF00567.19 ETO33234.1 - 9.6e-10 38.3 0.1 1.7e-09 37.5 0.1 1.6 1 1 0 1 1 1 1 Tudor domain SMN PF06003.7 ETO33234.1 - 0.00059 19.0 0.1 0.00078 18.6 0.1 1.3 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) 14-3-3 PF00244.15 ETO33234.1 - 0.0065 15.5 0.3 0.013 14.6 0.1 1.5 1 1 0 1 1 1 1 14-3-3 protein PWWP PF00855.12 ETO33234.1 - 0.11 12.6 0.2 0.76 10.0 0.1 2.2 1 1 0 1 1 1 0 PWWP domain DUF4494 PF14902.1 ETO33234.1 - 0.13 11.8 2.0 0.44 10.1 0.1 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4494) RabGAP-TBC PF00566.13 ETO33235.1 - 9.1e-08 31.8 7.1 9.1e-08 31.8 4.9 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain NS3_envE PF02723.9 ETO33235.1 - 0.22 11.4 3.6 0.57 10.1 2.5 1.6 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E Glycos_transf_2 PF00535.21 ETO33236.1 - 0.0095 15.6 0.0 0.035 13.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 2 MMS19_N PF14500.1 ETO33236.1 - 0.027 13.7 0.4 0.94 8.6 0.0 3.0 3 1 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II UCH PF00443.24 ETO33237.1 - 2.8e-17 62.7 1.4 2.8e-17 62.7 1.0 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-TRAF PF02176.13 ETO33237.1 - 2.6e-07 30.8 7.3 7.1e-07 29.5 0.8 2.8 2 0 0 2 2 2 2 TRAF-type zinc finger Endonuc-FokI_C PF09254.6 ETO33238.1 - 0.15 11.1 1.6 0.23 10.5 1.1 1.2 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal Phospholamban PF04272.9 ETO33238.1 - 4 6.9 5.7 0.76 9.2 1.3 1.7 2 0 0 2 2 2 0 Phospholamban Nucleoporin_N PF08801.6 ETO33239.1 - 0.0062 15.3 0.6 0.0088 14.8 0.4 1.2 1 0 0 1 1 1 1 Nup133 N terminal like M16C_assoc PF08367.6 ETO33239.1 - 0.018 13.8 5.4 0.18 10.6 0.7 2.2 1 1 1 2 2 2 0 Peptidase M16C associated Tup_N PF08581.5 ETO33239.1 - 0.21 11.8 0.2 0.21 11.8 0.1 2.6 3 0 0 3 3 3 0 Tup N-terminal Cortexin PF11057.3 ETO33239.1 - 8.9 5.9 6.7 18 5.0 4.3 1.8 1 1 0 1 1 1 0 Cortexin of kidney TPR_12 PF13424.1 ETO33240.1 - 3.6e-30 103.7 7.9 5.1e-11 42.3 0.0 4.8 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETO33240.1 - 6.3e-14 51.3 6.7 7.3e-07 28.7 0.9 4.2 4 0 0 4 4 4 3 TPR repeat TPR_2 PF07719.12 ETO33240.1 - 6.9e-12 44.3 8.6 0.01 15.6 0.2 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO33240.1 - 1.4e-10 40.3 12.4 0.00084 18.8 0.0 6.5 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO33240.1 - 9.6e-06 25.0 2.6 2.8 7.9 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat SNAP PF14938.1 ETO33240.1 - 5.2e-05 22.5 11.2 0.048 12.7 2.0 3.2 2 1 1 3 3 3 3 Soluble NSF attachment protein, SNAP TPR_10 PF13374.1 ETO33240.1 - 5.5e-05 22.9 0.0 2.3 8.2 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO33240.1 - 0.00012 22.1 11.7 0.00025 21.1 0.2 3.7 1 1 3 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 ETO33240.1 - 0.00013 22.2 0.0 3.9 8.3 0.0 4.6 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO33240.1 - 0.0003 21.0 3.7 14 6.4 0.0 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO33240.1 - 0.00057 19.0 0.1 0.087 12.0 0.0 3.5 4 0 0 4 4 4 1 SHNi-TPR SLT PF01464.15 ETO33240.1 - 0.0093 15.4 3.0 0.15 11.5 0.4 2.4 2 0 0 2 2 2 1 Transglycosylase SLT domain TPR_16 PF13432.1 ETO33240.1 - 0.027 15.1 0.4 67 4.3 0.0 4.3 3 2 1 4 4 4 0 Tetratricopeptide repeat Cyclin_C PF02984.14 ETO33240.1 - 0.059 13.2 0.5 0.1 12.4 0.3 1.4 1 0 0 1 1 1 0 Cyclin, C-terminal domain TPR_17 PF13431.1 ETO33240.1 - 0.06 13.5 0.5 19 5.7 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat Sel1 PF08238.7 ETO33240.1 - 0.067 13.8 0.0 0.26 11.9 0.0 2.1 1 0 0 1 1 1 0 Sel1 repeat TPR_8 PF13181.1 ETO33240.1 - 0.17 11.7 15.2 0.67 9.8 0.0 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat VWA_2 PF13519.1 ETO33241.1 - 4.5e-09 36.6 0.0 5.3e-08 33.1 0.0 2.7 2 0 0 2 2 2 1 von Willebrand factor type A domain SecA_DEAD PF07517.9 ETO33241.1 - 2.7e-08 33.4 0.0 2.7e-08 33.4 0.0 5.7 6 1 1 7 7 7 1 SecA DEAD-like domain Helicase_C PF00271.26 ETO33241.1 - 0.0011 18.8 0.0 0.014 15.2 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain VWA_2 PF13519.1 ETO33242.1 - 5.2e-09 36.4 0.0 8.3e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Helicase_C PF00271.26 ETO33242.1 - 2.7e-05 23.9 0.2 0.00011 21.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.9 ETO33243.1 - 3.6e-08 33.0 0.0 3.6e-08 33.0 0.0 4.7 4 1 0 4 4 4 1 SecA DEAD-like domain ABC_tran PF00005.22 ETO33243.1 - 0.0042 17.3 0.0 0.0042 17.3 0.0 5.0 3 1 0 3 3 3 1 ABC transporter AAA_29 PF13555.1 ETO33243.1 - 0.019 14.4 0.0 0.068 12.6 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 ETO33243.1 - 0.02 14.2 3.3 0.35 10.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 ETO33243.1 - 0.26 11.0 0.6 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain VWA_2 PF13519.1 ETO33244.1 - 1e-12 48.4 0.0 1.4e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain HAUS5 PF14817.1 ETO33244.1 - 0.048 12.2 0.2 0.071 11.6 0.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 DUF2208 PF09973.4 ETO33245.1 - 0.0093 15.2 4.0 0.013 14.7 2.8 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2208) NdhL PF10716.4 ETO33245.1 - 0.4 10.4 4.6 0.72 9.6 3.2 1.4 1 0 0 1 1 1 0 NADH dehydrogenase transmembrane subunit U-box PF04564.10 ETO33246.1 - 1.5e-19 69.7 0.1 1.5e-19 69.7 0.1 2.2 3 0 0 3 3 3 1 U-box domain zf-Nse PF11789.3 ETO33246.1 - 2.5e-05 23.7 0.0 6.3e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 ETO33246.1 - 0.00068 19.2 0.0 0.003 17.2 0.0 2.2 1 0 0 1 1 1 1 RING-type zinc-finger IPK PF03770.11 ETO33246.1 - 0.0014 18.3 0.2 0.7 9.5 0.1 2.3 2 0 0 2 2 2 2 Inositol polyphosphate kinase HABP4_PAI-RBP1 PF04774.10 ETO33246.1 - 0.055 13.9 1.0 0.097 13.1 0.7 1.5 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family Methyltransf_12 PF08242.7 ETO33246.1 - 0.21 12.0 2.4 0.28 11.6 1.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain RICH PF05062.7 ETO33246.1 - 0.92 9.6 8.7 0.1 12.7 2.8 1.8 2 0 0 2 2 2 0 RICH domain YfhO PF09586.5 ETO33246.1 - 2.1 6.2 12.8 2.6 5.9 8.9 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Tmemb_9 PF05434.6 ETO33246.1 - 7.7 6.2 7.8 8.4 6.1 1.9 2.4 1 1 1 2 2 2 0 TMEM9 PBP PF01161.15 ETO33247.1 - 8.5e-18 64.5 0.3 1.5e-17 63.8 0.2 1.4 1 1 1 2 2 2 1 Phosphatidylethanolamine-binding protein Hist_deacetyl PF00850.14 ETO33248.1 - 8.7e-21 74.5 0.0 1.1e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain GED PF02212.13 ETO33249.1 - 0.14 12.1 2.4 0.36 10.7 1.7 2.0 1 1 0 1 1 1 0 Dynamin GTPase effector domain UCH PF00443.24 ETO33251.1 - 5.1e-11 42.2 0.1 1e-10 41.1 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO33251.1 - 3.9e-08 33.1 1.0 5.6e-08 32.5 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase CopC PF04234.7 ETO33252.1 - 0.021 15.4 0.7 0.029 15.0 0.5 1.3 1 0 0 1 1 1 0 CopC domain BEN PF10523.4 ETO33253.1 - 0.099 12.7 0.8 0.18 11.9 0.6 1.7 1 1 0 1 1 1 0 BEN domain WD40 PF00400.27 ETO33254.1 - 5.1e-22 76.8 9.2 1.7e-10 40.3 0.0 4.5 5 1 0 5 5 5 3 WD domain, G-beta repeat Endonuc_subdom PF09062.5 ETO33254.1 - 0.44 11.3 2.7 0.68 10.7 0.1 2.4 2 1 1 3 3 3 0 PI-PfuI Endonuclease subdomain WD40 PF00400.27 ETO33255.1 - 8.1e-07 28.6 0.7 0.0014 18.4 0.0 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO33255.1 - 0.0038 16.0 0.6 0.0052 15.5 0.4 1.1 1 0 0 1 1 1 1 Nup133 N terminal like WD40 PF00400.27 ETO33256.1 - 1.6e-57 189.4 14.3 2.7e-12 46.0 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO33256.1 - 1.2e-12 46.8 1.0 0.00029 19.1 0.0 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO33256.1 - 1.3e-12 47.8 0.7 2.6e-05 23.9 0.0 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO33256.1 - 6.6e-08 31.2 1.4 0.002 16.4 0.1 2.8 1 1 0 2 2 2 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO33256.1 - 2.4e-05 23.8 0.0 0.00035 20.1 0.0 2.0 1 1 0 1 1 1 1 PQQ-like domain Nucleoporin_N PF08801.6 ETO33256.1 - 6.3e-05 21.9 9.8 0.23 10.1 0.5 4.2 2 2 1 3 3 3 3 Nup133 N terminal like DPPIV_N PF00930.16 ETO33256.1 - 6.8e-05 21.6 0.2 0.014 13.9 0.0 3.1 1 1 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PQQ PF01011.16 ETO33256.1 - 0.0031 16.9 0.0 5.4 6.7 0.0 3.4 3 0 0 3 3 3 1 PQQ enzyme repeat Str_synth PF03088.11 ETO33256.1 - 0.0056 16.6 0.2 11 6.0 0.0 3.7 3 2 0 3 3 3 1 Strictosidine synthase IKI3 PF04762.7 ETO33256.1 - 0.011 13.6 4.3 0.39 8.4 0.0 2.8 2 1 1 3 3 3 0 IKI3 family PD40 PF07676.7 ETO33256.1 - 0.014 15.0 7.1 9.5 6.0 0.1 5.0 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Hira PF07569.6 ETO33256.1 - 0.024 13.8 0.2 6.8 5.8 0.0 3.4 2 1 1 3 3 3 0 TUP1-like enhancer of split Myosin_tail_1 PF01576.14 ETO33257.1 - 0.15 9.7 25.5 0.29 8.7 17.7 1.4 1 1 0 1 1 1 0 Myosin tail WD40 PF00400.27 ETO33258.1 - 1.6e-20 72.1 10.0 3.4e-08 33.0 0.2 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO33258.1 - 3e-07 28.9 2.0 0.0012 17.0 0.1 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Kelch_4 PF13418.1 ETO33259.1 - 0.0022 17.7 0.0 1.4 8.7 0.0 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO33259.1 - 0.01 15.9 0.1 26 5.1 0.0 4.4 4 1 1 5 5 5 0 Kelch motif YqfQ PF14181.1 ETO33260.1 - 0.73 9.8 11.1 1.7 8.6 7.7 1.6 1 0 0 1 1 1 0 YqfQ-like protein Sporozoite_P67 PF05642.6 ETO33260.1 - 1.5 6.6 8.8 2 6.1 6.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Gal_Lectin PF02140.13 ETO33260.1 - 1.6 9.0 6.7 2.5 8.5 0.1 2.4 2 0 0 2 2 2 0 Galactose binding lectin domain GCD14 PF08704.5 ETO33260.1 - 5.5 6.3 10.0 1.1 8.6 3.9 1.9 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit DUF2797 PF10977.3 ETO33261.1 - 0.033 13.8 0.1 0.043 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) Ribosomal_S21 PF01165.15 ETO33261.1 - 0.11 11.9 0.0 0.26 10.7 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S21 PUB PF09409.5 ETO33261.1 - 0.12 12.1 2.5 0.46 10.2 0.3 2.5 3 0 0 3 3 3 0 PUB domain CW_binding_1 PF01473.15 ETO33264.1 - 0.079 13.1 1.7 0.079 13.1 1.2 2.6 3 0 0 3 3 3 0 Putative cell wall binding repeat PUB PF09409.5 ETO33264.1 - 0.091 12.5 11.3 0.2 11.4 2.6 3.3 1 1 1 2 2 2 0 PUB domain Staphopain_pro PF14731.1 ETO33264.1 - 0.55 9.9 8.2 0.91 9.2 0.8 2.4 2 0 0 2 2 2 0 Staphopain proregion RRM_1 PF00076.17 ETO33265.1 - 7.2e-15 54.3 0.6 2.8e-14 52.4 0.0 2.1 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO33265.1 - 1.4e-10 40.9 0.0 2.3e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO33265.1 - 4.4e-10 39.2 0.2 6.4e-10 38.7 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETO33265.1 - 0.0012 18.5 0.4 0.004 16.8 0.0 1.9 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.6 ETO33265.1 - 0.005 16.8 0.0 0.0092 15.9 0.0 1.5 1 0 0 1 1 1 1 RNA binding domain LicD PF04991.8 ETO33265.1 - 0.043 13.9 3.1 0.049 13.7 2.2 1.1 1 0 0 1 1 1 0 LicD family Cellulose_synt PF03552.9 ETO33265.1 - 0.16 10.2 2.4 0.18 10.1 1.6 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF2208 PF09973.4 ETO33265.1 - 0.2 10.8 1.7 0.3 10.3 1.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) OATP PF03137.15 ETO33265.1 - 0.23 9.4 2.6 0.3 9.0 1.8 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family PDCD2_C PF04194.8 ETO33265.1 - 0.61 9.6 6.8 0.89 9.1 4.7 1.2 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain YqfQ PF14181.1 ETO33265.1 - 4.6 7.2 8.6 6.5 6.7 6.0 1.2 1 0 0 1 1 1 0 YqfQ-like protein Med7 PF05983.6 ETO33266.1 - 1.4e-07 31.4 13.0 1.2e-06 28.4 9.0 2.2 1 1 0 1 1 1 1 MED7 protein DUF2981 PF11200.3 ETO33266.1 - 0.032 13.3 0.1 0.041 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) YlbD_coat PF14071.1 ETO33266.1 - 0.048 13.7 3.0 0.075 13.0 2.1 1.4 1 0 0 1 1 1 0 Putative coat protein PTS-HPr PF00381.14 ETO33266.1 - 0.08 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 PTS HPr component phosphorylation site ACP_syn_III_C PF08541.5 ETO33266.1 - 0.11 12.4 0.7 6.1 6.9 0.1 2.2 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ELK PF03789.8 ETO33266.1 - 0.14 11.9 1.1 0.24 11.2 0.8 1.3 1 0 0 1 1 1 0 ELK domain DUF3728 PF12528.3 ETO33266.1 - 0.32 11.4 3.0 0.24 11.8 0.9 1.6 1 1 0 1 1 1 0 Prepilin peptidase dependent protein C (DUF3728) Spt5-NGN PF03439.8 ETO33267.1 - 2e-09 37.0 0.0 4.5e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section SPX PF03105.14 ETO33267.1 - 0.068 12.9 11.8 0.092 12.5 8.1 1.2 1 0 0 1 1 1 0 SPX domain Mucin PF01456.12 ETO33267.1 - 0.27 11.0 8.3 2.9 7.6 5.8 2.1 1 1 0 1 1 1 0 Mucin-like glycoprotein DUF1675 PF07897.6 ETO33267.1 - 0.69 9.7 9.4 1.1 9.0 6.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) WD40 PF00400.27 ETO33268.1 - 3.7e-70 229.4 22.5 4.2e-12 45.4 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO33268.1 - 1.9e-07 29.6 3.9 1.1 7.2 0.0 5.6 3 2 3 6 6 6 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO33268.1 - 0.0016 17.3 4.4 3.1 6.4 0.0 4.6 2 1 1 4 4 4 3 Nup133 N terminal like PPR PF01535.15 ETO33271.1 - 1.1e-09 37.6 5.8 0.0002 21.1 0.1 4.0 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.1 ETO33271.1 - 1.4e-08 34.3 0.0 0.0024 18.0 0.0 4.2 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 ETO33271.1 - 1.5e-08 34.5 8.9 0.00013 21.8 0.0 4.9 5 0 0 5 5 5 2 PPR repeat family PPR_1 PF12854.2 ETO33271.1 - 0.0003 20.2 0.0 0.015 14.7 0.0 2.9 3 0 0 3 3 3 1 PPR repeat DUF1847 PF08901.6 ETO33271.1 - 0.047 13.2 1.2 0.095 12.2 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1847) DUF982 PF06169.7 ETO33271.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF982) TPR_19 PF14559.1 ETO33271.1 - 0.13 12.5 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat VWA_2 PF13519.1 ETO33272.1 - 2.5e-06 27.7 0.0 3.2e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain MoeA_N PF03453.12 ETO33274.1 - 6.3e-24 84.1 0.1 8.1e-24 83.8 0.1 1.1 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) Glyco_hydro_47 PF01532.15 ETO33275.1 - 7.5e-94 314.9 8.3 9.9e-94 314.5 5.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 IL15 PF02372.10 ETO33276.1 - 0.042 13.6 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Interleukin 15 MltA PF03562.12 ETO33278.1 - 0.04 13.6 0.1 0.071 12.8 0.1 1.5 1 1 0 1 1 1 0 MltA specific insert domain Spc7_N PF15402.1 ETO33278.1 - 3.2 5.6 9.6 3.5 5.5 6.6 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 WD40 PF00400.27 ETO33280.1 - 3.4e-11 42.5 2.6 8.1e-11 41.3 0.2 2.4 2 1 0 2 2 2 1 WD domain, G-beta repeat Nop14 PF04147.7 ETO33281.1 - 0.68 7.7 30.3 0.86 7.4 21.0 1.1 1 0 0 1 1 1 0 Nop14-like family WD40 PF00400.27 ETO33282.1 - 6.5e-52 171.6 21.0 3e-11 42.7 0.6 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO33282.1 - 4.2e-14 51.6 4.5 0.00038 18.7 0.1 5.8 1 1 3 5 5 5 5 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO33282.1 - 0.015 15.0 2.7 0.63 9.8 0.1 3.8 2 2 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region HAD PF12710.2 ETO33282.1 - 0.044 13.9 1.1 0.7 10.0 0.1 2.8 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Amidase PF01425.16 ETO33284.1 - 2.2e-11 43.2 0.0 1.6e-10 40.4 0.0 1.9 1 1 0 1 1 1 1 Amidase TPR_11 PF13414.1 ETO33285.1 - 4.1e-19 67.9 9.6 2.7e-11 42.9 0.0 4.0 2 2 1 4 4 4 4 TPR repeat TPR_2 PF07719.12 ETO33285.1 - 3e-15 54.8 5.7 0.00051 19.7 0.1 5.2 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO33285.1 - 2.5e-14 52.1 15.2 6.3e-07 28.7 0.2 5.3 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO33285.1 - 3e-12 45.3 11.3 0.00022 20.7 0.1 5.6 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO33285.1 - 6e-11 41.6 7.3 0.026 14.7 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO33285.1 - 6.3e-09 36.2 0.0 0.0011 19.6 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO33285.1 - 6e-07 29.3 1.3 0.0011 18.8 0.5 3.7 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO33285.1 - 3e-05 24.2 0.0 0.29 11.8 0.0 4.3 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO33285.1 - 0.00018 21.0 3.4 0.18 11.6 0.0 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO33285.1 - 0.00046 20.4 4.4 0.012 15.9 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Rif1_N PF12231.3 ETO33285.1 - 0.00091 18.2 0.0 0.18 10.7 0.0 2.2 2 0 0 2 2 2 2 Rap1-interacting factor 1 N terminal TPR_20 PF14561.1 ETO33285.1 - 0.0026 17.8 1.1 0.35 11.0 0.3 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF627 PF04781.7 ETO33285.1 - 0.023 14.3 0.2 0.066 12.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF627) TPR_6 PF13174.1 ETO33285.1 - 0.075 13.5 0.3 80 4.0 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.12 ETO33285.1 - 0.084 13.1 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 Bacterial transcriptional activator domain MIT PF04212.13 ETO33285.1 - 0.087 12.7 5.1 1.3 8.9 0.7 3.3 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain ERG4_ERG24 PF01222.12 ETO33286.1 - 5.6e-77 259.1 20.8 6.5e-77 258.8 14.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 ETO33286.1 - 2.1e-07 30.4 3.3 3.2e-07 29.8 2.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 ETO33286.1 - 0.004 17.3 0.0 0.0097 16.0 0.0 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF3139 PF11337.3 ETO33286.1 - 0.13 12.5 1.2 0.28 11.5 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Ribosomal_L22e PF01776.12 ETO33287.1 - 0.048 13.6 3.6 0.038 13.9 0.9 1.9 2 0 0 2 2 2 0 Ribosomal L22e protein family Vpu PF00558.14 ETO33288.1 - 0.018 14.6 0.2 0.032 13.7 0.1 1.4 1 0 0 1 1 1 0 Vpu protein DUF2072 PF09845.4 ETO33288.1 - 0.052 13.4 1.2 0.057 13.3 0.5 1.3 1 1 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) WD40 PF00400.27 ETO33289.1 - 3.9e-08 32.8 1.5 0.016 15.0 0.0 3.5 3 1 0 3 3 3 2 WD domain, G-beta repeat Neisseria_PilC PF05567.6 ETO33289.1 - 0.047 12.7 0.0 0.095 11.7 0.0 1.5 1 1 1 2 2 2 0 Neisseria PilC beta-propeller domain Myosin_head PF00063.16 ETO33290.1 - 0.0093 14.0 3.6 0.01 13.8 2.5 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) CAF-1_p150 PF11600.3 ETO33290.1 - 0.035 13.4 16.0 0.046 13.0 11.0 1.3 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Urocanase PF01175.13 ETO33290.1 - 0.066 11.2 0.5 0.073 11.0 0.3 1.1 1 0 0 1 1 1 0 Urocanase ICAP-1_inte_bdg PF10480.4 ETO33290.1 - 0.099 12.4 8.9 0.13 12.0 6.2 1.1 1 0 0 1 1 1 0 Beta-1 integrin binding protein EPL1 PF10513.4 ETO33290.1 - 0.52 10.5 12.6 0.16 12.2 7.0 1.4 1 1 0 1 1 1 0 Enhancer of polycomb-like DUF2457 PF10446.4 ETO33290.1 - 0.77 8.4 16.0 0.92 8.1 11.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF572 PF04502.8 ETO33290.1 - 1.8 7.6 15.4 2 7.5 10.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) SR-25 PF10500.4 ETO33290.1 - 2.5 7.4 29.6 15 5.0 20.5 1.9 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.4 ETO33290.1 - 3 6.0 22.4 3.3 5.8 15.5 1.0 1 0 0 1 1 1 0 Transmembrane protein TFIIF_alpha PF05793.7 ETO33290.1 - 4 5.7 20.3 4.3 5.5 14.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) NST1 PF13945.1 ETO33290.1 - 4.2 7.3 16.4 5.1 7.1 11.3 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Sporozoite_P67 PF05642.6 ETO33290.1 - 4.8 4.9 17.5 5.3 4.7 12.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BNIP3 PF06553.7 ETO33290.1 - 5.2 6.3 17.6 6.3 6.1 12.2 1.2 1 0 0 1 1 1 0 BNIP3 PRP21_like_P PF12230.3 ETO33291.1 - 2.1e-24 86.3 11.5 8.2e-14 51.6 0.7 2.5 1 1 1 2 2 2 2 Pre-mRNA splicing factor PRP21 like protein DUF3439 PF11921.3 ETO33291.1 - 0.017 14.8 3.4 0.037 13.7 2.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 ETO33291.1 - 0.2 11.4 11.8 0.43 10.3 8.2 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Pex14_N PF04695.8 ETO33291.1 - 1.1 9.3 12.2 2.5 8.1 5.1 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Nop14 PF04147.7 ETO33291.1 - 1.9 6.2 19.5 1.6 6.5 10.6 2.1 2 0 0 2 2 2 0 Nop14-like family Menin PF05053.8 ETO33291.1 - 4.3 5.3 10.8 0.49 8.4 4.0 1.9 2 0 0 2 2 2 0 Menin Rootletin PF15035.1 ETO33292.1 - 0.001 19.0 4.3 0.0017 18.3 3.0 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion HALZ PF02183.13 ETO33292.1 - 0.0061 16.2 0.7 0.19 11.5 0.1 2.3 2 0 0 2 2 2 1 Homeobox associated leucine zipper KIAA1430 PF13879.1 ETO33292.1 - 0.026 14.9 2.3 0.026 14.9 1.6 1.6 2 0 0 2 2 2 0 KIAA1430 homologue DUF972 PF06156.8 ETO33292.1 - 0.25 11.7 1.4 0.42 10.9 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) APG6 PF04111.7 ETO33292.1 - 0.26 10.2 3.1 0.37 9.8 2.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 ETO33292.1 - 0.29 10.7 5.2 0.51 9.9 3.6 1.3 1 0 0 1 1 1 0 IncA protein SKG6 PF08693.5 ETO33293.1 - 2.1e-05 23.7 1.6 3.6e-05 22.9 1.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 ETO33293.1 - 0.00019 20.9 0.0 0.00024 20.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.1 ETO33293.1 - 0.00098 18.8 0.1 0.0012 18.5 0.1 1.2 1 0 0 1 1 1 1 TMEM154 protein family DAG1 PF05454.6 ETO33293.1 - 0.00099 18.3 0.1 0.0012 18.1 0.1 1.2 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) CD34_antigen PF06365.7 ETO33293.1 - 0.001 18.7 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family DUF2615 PF11027.3 ETO33293.1 - 0.0037 17.1 0.1 0.0063 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) Adeno_E3_CR2 PF02439.10 ETO33293.1 - 0.0088 15.5 0.5 0.015 14.8 0.3 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF912 PF06024.7 ETO33293.1 - 0.01 15.8 0.1 0.015 15.3 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Plasmodium_Vir PF05795.6 ETO33293.1 - 0.011 14.9 0.1 0.013 14.6 0.1 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Herpes_gE PF02480.11 ETO33293.1 - 0.016 13.5 0.5 0.029 12.6 0.3 1.4 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E DUF4366 PF14283.1 ETO33293.1 - 0.017 14.5 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) BatD PF13584.1 ETO33293.1 - 0.018 13.6 0.1 0.022 13.3 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF4381 PF14316.1 ETO33293.1 - 0.02 14.9 0.1 0.052 13.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) EphA2_TM PF14575.1 ETO33293.1 - 0.027 14.8 0.1 0.065 13.6 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain GRA6 PF05084.8 ETO33293.1 - 0.037 13.5 0.0 0.047 13.2 0.0 1.1 1 0 0 1 1 1 0 Granule antigen protein (GRA6) DUF1180 PF06679.7 ETO33293.1 - 0.037 13.8 0.0 0.047 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Peptidase_M56 PF05569.6 ETO33293.1 - 0.042 12.8 0.1 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 Protocadherin PF08374.6 ETO33293.1 - 0.043 13.4 0.1 0.058 13.0 0.1 1.2 1 0 0 1 1 1 0 Protocadherin TMEM51 PF15345.1 ETO33293.1 - 0.046 13.4 0.1 0.06 13.0 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Viral_Beta_CD PF04530.7 ETO33293.1 - 0.059 13.5 0.0 0.084 13.0 0.0 1.2 1 0 0 1 1 1 0 Viral Beta C/D like family IncA PF04156.9 ETO33293.1 - 0.07 12.7 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 IncA protein Antimicrobial_7 PF08102.6 ETO33293.1 - 0.077 13.0 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Scorpion antimicrobial peptide DUF4083 PF13314.1 ETO33293.1 - 0.088 12.6 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) DUF2561 PF10812.3 ETO33293.1 - 0.096 12.2 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) BH4 PF02180.12 ETO33293.1 - 0.096 12.1 0.7 8.6 5.9 0.0 2.3 2 0 0 2 2 2 0 Bcl-2 homology region 4 EssA PF10661.4 ETO33293.1 - 0.11 12.1 0.3 0.19 11.3 0.2 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA DUF3040 PF11239.3 ETO33293.1 - 0.11 12.5 0.0 8 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) ETRAMP PF09716.5 ETO33293.1 - 0.21 11.5 1.9 0.42 10.5 0.2 1.9 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Tox-SHH PF15652.1 ETO33294.1 - 0.06 13.9 0.7 0.06 13.9 0.5 2.2 2 0 0 2 2 2 0 HNH/Endo VII superfamily toxin with a SHH signature SNAP PF14938.1 ETO33295.1 - 5.5e-17 61.8 3.8 5.7e-17 61.7 2.6 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP PPR_2 PF13041.1 ETO33295.1 - 0.0016 18.3 0.0 0.0044 16.9 0.0 1.7 2 0 0 2 2 2 1 PPR repeat family MIT PF04212.13 ETO33295.1 - 0.007 16.2 0.8 0.95 9.3 0.4 2.5 1 1 0 1 1 1 1 MIT (microtubule interacting and transport) domain NSF PF02071.15 ETO33295.1 - 0.019 15.4 3.0 2.7 8.9 0.1 4.1 4 1 0 4 4 4 0 Aromatic-di-Alanine (AdAR) repeat TPR_12 PF13424.1 ETO33295.1 - 0.032 14.1 0.8 0.049 13.5 0.6 1.4 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETO33295.1 - 0.055 13.4 4.3 10 6.3 0.1 3.7 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 ETO33295.1 - 0.092 12.4 2.7 6.8 6.4 0.1 2.9 1 1 0 2 2 2 0 TPR repeat TPR_1 PF00515.23 ETO33295.1 - 0.095 12.3 2.7 15 5.3 0.0 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat Peptidase_C14 PF00656.17 ETO33296.1 - 4.3e-07 29.8 0.8 8.6e-07 28.9 0.5 1.4 1 0 0 1 1 1 1 Caspase domain Kelch_4 PF13418.1 ETO33296.1 - 0.015 15.0 0.1 0.24 11.2 0.0 2.4 1 1 1 2 2 2 0 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO33296.1 - 0.039 13.4 0.3 4.6 6.8 0.1 2.7 2 0 0 2 2 2 0 Kelch motif Cid2 PF09774.4 ETO33297.1 - 0.016 15.3 1.4 0.016 15.3 1.0 1.7 2 0 0 2 2 2 0 Caffeine-induced death protein 2 DUF3853 PF12964.2 ETO33297.1 - 0.026 14.3 1.5 0.04 13.7 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3853) SIR2 PF02146.12 ETO33297.1 - 0.076 12.7 0.3 0.076 12.7 0.2 1.9 2 0 0 2 2 2 0 Sir2 family Peptidase_C6 PF00851.13 ETO33297.1 - 3.9 6.0 11.6 5.1 5.6 8.1 1.1 1 0 0 1 1 1 0 Helper component proteinase Ank_4 PF13637.1 ETO33298.1 - 3.4e-07 30.6 0.4 5.1e-05 23.6 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 ETO33298.1 - 6.4e-07 28.8 0.2 6.1e-05 22.6 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 ETO33298.1 - 4.9e-05 23.1 0.8 0.03 14.5 0.0 3.4 3 1 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 ETO33298.1 - 5.5e-05 23.4 0.1 0.00027 21.2 0.0 2.2 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO33298.1 - 0.02 15.1 2.0 0.11 12.8 0.1 2.9 3 1 0 3 3 3 0 Ankyrin repeats (many copies) Rtf2 PF04641.7 ETO33298.1 - 1.7 7.8 11.2 2.5 7.2 7.8 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger RabGAP-TBC PF00566.13 ETO33299.1 - 0.13 11.7 1.7 0.14 11.5 1.2 1.1 1 0 0 1 1 1 0 Rab-GTPase-TBC domain PH_4 PF15404.1 ETO33301.1 - 0.042 13.3 1.7 0.044 13.2 1.2 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain Cellulase-like PF12876.2 ETO33301.1 - 0.18 12.2 0.5 0.23 11.9 0.3 1.3 1 1 0 1 1 1 0 Sugar-binding cellulase-like WBS_methylT PF12589.3 ETO33301.1 - 0.87 10.1 10.1 0.51 10.8 5.2 1.8 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome Kelch_1 PF01344.20 ETO33303.1 - 5.3e-06 25.8 1.0 0.00067 19.1 0.2 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETO33303.1 - 5.3e-05 22.9 0.4 0.017 14.8 0.0 3.2 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO33303.1 - 5.6e-05 22.7 1.1 0.059 13.1 0.1 3.4 3 1 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO33303.1 - 0.00011 22.1 2.4 0.0072 16.4 0.1 3.7 3 1 1 4 4 4 1 Kelch motif Kelch_5 PF13854.1 ETO33303.1 - 0.13 12.2 4.3 1.2 9.2 0.1 3.2 4 0 0 4 4 4 0 Kelch motif WD40 PF00400.27 ETO33304.1 - 1.8e-44 148.0 32.3 8.3e-10 38.1 0.2 7.4 6 2 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO33304.1 - 8e-12 44.0 3.6 0.01 14.0 0.0 5.1 1 1 3 5 5 5 5 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO33304.1 - 9.8e-05 22.1 2.9 0.26 11.0 0.1 4.6 2 2 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region HAD PF12710.2 ETO33304.1 - 0.15 12.2 1.9 61 3.7 1.3 3.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Atg14 PF10186.4 ETO33304.1 - 0.92 8.3 9.9 1.5 7.7 6.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 zf-C3HC4_2 PF13923.1 ETO33305.1 - 0.0034 17.3 1.0 0.042 13.8 0.7 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO33305.1 - 0.027 14.2 0.7 0.1 12.4 0.5 1.9 1 1 0 1 1 1 0 Ring finger domain DUF723 PF05265.8 ETO33305.1 - 0.13 12.0 1.1 0.16 11.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF723) zf-C3HC4 PF00097.20 ETO33305.1 - 0.61 9.8 3.8 13 5.5 0.0 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 ETO33305.1 - 1.3 8.9 4.9 0.63 9.9 1.2 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING AMP-binding PF00501.23 ETO33306.1 - 6.8e-37 126.8 0.1 8.7e-37 126.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Tom37_C PF11801.3 ETO33307.1 - 0.072 12.9 7.2 0.095 12.5 5.0 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain TraH PF06122.6 ETO33307.1 - 0.2 10.4 2.6 0.24 10.1 1.8 1.1 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein Cellulose_synt PF03552.9 ETO33307.1 - 0.38 8.9 3.0 0.47 8.6 2.0 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF4337 PF14235.1 ETO33307.1 - 0.77 9.5 4.4 1.2 9.0 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DDHD PF02862.12 ETO33307.1 - 1.5 8.5 7.0 1.9 8.2 4.9 1.2 1 0 0 1 1 1 0 DDHD domain CCDC66 PF15236.1 ETO33307.1 - 1.5 8.3 24.2 2.3 7.8 16.8 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 U79_P34 PF03064.11 ETO33307.1 - 2.1 7.7 12.8 2.7 7.4 8.9 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Trypan_PARP PF05887.6 ETO33307.1 - 2.8 7.7 8.2 3.9 7.2 5.7 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) WD40 PF00400.27 ETO33308.1 - 3e-70 229.8 19.1 3.5e-13 48.8 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO33308.1 - 2.1e-10 39.4 6.7 0.01 14.0 0.0 5.0 1 1 5 6 6 6 4 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO33308.1 - 1.6e-09 37.7 0.3 0.001 18.8 0.0 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO33308.1 - 2.3e-05 22.9 1.0 0.009 14.3 0.1 2.9 1 1 2 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO33308.1 - 3e-05 22.9 11.8 0.89 8.2 0.4 5.6 2 1 3 5 5 5 3 Nup133 N terminal like PQQ_2 PF13360.1 ETO33308.1 - 0.0001 21.8 1.5 0.0004 19.9 0.6 2.2 2 1 0 2 2 2 1 PQQ-like domain PD40 PF07676.7 ETO33308.1 - 0.00029 20.4 4.9 5.8 6.6 0.2 4.4 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 ETO33308.1 - 0.0041 16.2 0.3 0.37 9.8 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1258) Mid2 PF04478.7 ETO33308.1 - 0.0058 16.0 8.1 5.1 6.4 0.0 4.7 3 1 2 5 5 5 1 Mid2 like cell wall stress sensor Proteasome_A_N PF10584.4 ETO33308.1 - 1.7 8.0 8.1 22 4.5 0.0 4.6 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature TPR_12 PF13424.1 ETO33309.1 - 6.2e-27 93.3 1.5 2.3e-14 53.0 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO33309.1 - 3.2e-16 58.7 4.8 5.7e-10 38.7 0.1 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETO33309.1 - 2e-14 52.4 14.1 6e-08 31.9 0.2 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO33309.1 - 4.8e-12 44.7 3.3 7.8e-07 28.4 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO33309.1 - 1e-10 40.6 7.5 0.00015 21.4 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO33309.1 - 6.4e-10 38.0 18.7 0.00011 21.6 0.2 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO33309.1 - 2.8e-05 24.2 1.9 1.3 9.6 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat SNAP PF14938.1 ETO33309.1 - 9.9e-05 21.6 4.5 0.00042 19.5 1.0 2.2 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP Apc3 PF12895.2 ETO33309.1 - 0.00011 22.2 3.2 0.00011 22.2 2.2 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 ETO33309.1 - 0.00022 21.0 0.0 0.022 14.6 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO33309.1 - 0.00066 19.6 4.2 0.092 12.9 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.4 ETO33309.1 - 0.00099 18.5 3.5 0.25 10.6 0.2 2.7 1 1 1 2 2 2 2 26S proteasome subunit RPN7 MIT PF04212.13 ETO33309.1 - 0.011 15.6 8.3 0.23 11.3 0.1 3.5 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.1 ETO33309.1 - 0.046 14.3 0.0 65 4.5 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETO33309.1 - 0.18 12.5 0.0 8.5 7.1 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.7 ETO33309.1 - 5.4 6.9 10.4 1.5 8.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Senescence PF06911.7 ETO33312.1 - 0.002 17.8 4.1 0.29 10.8 0.7 2.4 1 1 1 2 2 2 2 Senescence-associated protein Prominin PF05478.6 ETO33312.1 - 0.14 9.7 5.7 0.28 8.6 4.0 1.5 1 0 0 1 1 1 0 Prominin ATP-synt_B PF00430.13 ETO33312.1 - 0.61 9.8 16.3 1.2 9.0 4.6 2.8 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DASH_Duo1 PF08651.5 ETO33312.1 - 0.83 9.2 10.2 0.89 9.1 1.2 3.0 2 1 1 3 3 3 0 DASH complex subunit Duo1 FliJ PF02050.11 ETO33312.1 - 1.4 8.9 15.5 0.25 11.3 4.2 3.1 3 0 0 3 3 3 0 Flagellar FliJ protein HisKA_3 PF07730.8 ETO33312.1 - 1.5 9.2 6.9 1.3 9.3 0.2 3.4 1 1 2 3 3 3 0 Histidine kinase DUF883 PF05957.8 ETO33312.1 - 2.2 8.7 15.0 2 8.8 4.5 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) TMP_2 PF06791.8 ETO33312.1 - 2.5 7.6 8.2 1.2 8.6 1.6 2.2 1 1 1 2 2 2 0 Prophage tail length tape measure protein Tweety PF04906.8 ETO33312.1 - 3.1 6.0 9.8 33 2.7 6.8 2.3 1 1 0 1 1 1 0 Tweety DUF948 PF06103.6 ETO33312.1 - 3.4 7.6 22.0 0.18 11.7 5.7 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.7 ETO33312.1 - 7.5 6.3 15.5 35 4.1 10.6 2.3 1 1 0 1 1 1 0 Laminin Domain II ABC_tran PF00005.22 ETO33313.1 - 2.7e-25 89.2 0.6 1.2e-24 87.2 0.0 2.3 2 1 0 2 2 2 1 ABC transporter SMC_N PF02463.14 ETO33313.1 - 1.1e-06 28.1 1.0 2.8e-05 23.4 0.7 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETO33313.1 - 1.4e-05 25.2 0.2 0.0002 21.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 ETO33313.1 - 2.4e-05 23.8 0.0 0.15 11.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 ETO33313.1 - 0.00011 21.4 0.5 0.00021 20.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 ETO33313.1 - 0.00031 20.8 0.0 0.16 12.1 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.1 ETO33313.1 - 0.00035 20.0 0.1 0.0008 18.8 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 ETO33313.1 - 0.0008 19.4 1.2 0.016 15.2 0.8 2.3 1 1 0 1 1 1 1 AAA ATPase domain SbcCD_C PF13558.1 ETO33313.1 - 0.00084 19.2 0.6 0.0052 16.6 0.4 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.10 ETO33313.1 - 0.0013 18.4 0.7 0.59 9.8 0.0 2.5 2 1 0 2 2 2 1 NTPase AAA_30 PF13604.1 ETO33313.1 - 0.0016 18.0 4.1 0.033 13.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ETO33313.1 - 0.0032 18.2 0.0 0.019 15.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETO33313.1 - 0.0041 17.4 1.1 0.046 14.0 0.0 2.8 2 1 0 3 3 3 1 AAA domain AAA PF00004.24 ETO33313.1 - 0.0046 17.1 1.3 0.25 11.5 0.0 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETO33313.1 - 0.006 16.3 0.0 0.21 11.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 ETO33313.1 - 0.0082 16.0 0.6 0.15 11.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain T2SE PF00437.15 ETO33313.1 - 0.018 13.9 1.5 0.079 11.8 0.1 2.2 2 1 0 2 2 2 0 Type II/IV secretion system protein MobB PF03205.9 ETO33313.1 - 0.022 14.4 0.1 0.06 13.0 0.1 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 ETO33313.1 - 0.029 13.8 0.2 0.079 12.4 0.1 1.6 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.12 ETO33313.1 - 0.039 13.3 0.1 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein LAGLIDADG_WhiA PF14527.1 ETO33313.1 - 0.049 13.5 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain NACHT PF05729.7 ETO33313.1 - 0.14 11.8 1.4 0.23 11.0 0.2 1.8 2 0 0 2 2 2 0 NACHT domain Miro PF08477.8 ETO33313.1 - 0.21 12.0 1.8 0.41 11.1 0.2 2.3 2 1 0 2 2 2 0 Miro-like protein AAA_15 PF13175.1 ETO33313.1 - 0.28 10.1 8.3 0.062 12.3 0.4 2.4 2 1 0 2 2 2 0 AAA ATPase domain PglZ PF08665.7 ETO33313.1 - 0.81 9.3 5.9 0.65 9.6 1.8 2.3 2 1 1 3 3 3 0 PglZ domain AAA_23 PF13476.1 ETO33313.1 - 1.4 9.1 9.7 12 6.1 6.5 2.3 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 ETO33313.1 - 5.7 6.4 8.2 0.97 8.9 0.4 2.8 2 1 0 3 3 3 0 AAA domain WD40 PF00400.27 ETO33314.1 - 1.7e-36 122.7 17.5 2.3e-09 36.7 0.1 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO33314.1 - 7.3e-08 30.9 1.2 0.022 12.9 0.0 3.7 1 1 2 3 3 3 2 Nucleoporin Nup120/160 DUF4629 PF15442.1 ETO33315.1 - 0.05 13.7 17.6 0.067 13.3 12.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) KBP_C PF12309.3 ETO33315.1 - 0.097 11.6 4.5 0.12 11.3 3.1 1.1 1 0 0 1 1 1 0 KIF-1 binding protein C terminal Raftlin PF15250.1 ETO33315.1 - 0.5 8.8 8.0 0.53 8.7 5.6 1.0 1 0 0 1 1 1 0 Raftlin Tim54 PF11711.3 ETO33315.1 - 1.2 7.6 15.3 1.4 7.4 10.6 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 MIP-T3 PF10243.4 ETO33315.1 - 2.2 6.6 23.4 2.3 6.5 16.2 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF4554 PF15091.1 ETO33315.1 - 2.5 6.7 7.3 2.7 6.6 5.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) DUF4045 PF13254.1 ETO33315.1 - 2.9 7.0 16.9 3.1 6.9 11.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Dsh_C PF12316.3 ETO33315.1 - 3 7.9 8.0 3.5 7.6 5.5 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal AUX_IAA PF02309.11 ETO33315.1 - 3.9 7.1 9.7 4.8 6.8 6.7 1.2 1 0 0 1 1 1 0 AUX/IAA family DUF1510 PF07423.6 ETO33315.1 - 4.8 6.4 21.0 6.7 6.0 14.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 ETO33315.1 - 5.7 4.8 7.0 5.4 4.9 4.8 1.0 1 0 0 1 1 1 0 CDC45-like protein TEX19 PF15553.1 ETO33315.1 - 6.2 6.6 7.4 8.1 6.2 5.1 1.1 1 0 0 1 1 1 0 Testis-expressed protein 19 NPR3 PF03666.8 ETO33315.1 - 6.6 5.1 10.9 7.7 4.9 7.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3987 PF13148.1 ETO33315.1 - 6.8 5.1 9.7 8.9 4.7 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) GAGA_bind PF06217.7 ETO33315.1 - 7.2 6.4 11.4 7.3 6.4 7.9 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Menin PF05053.8 ETO33315.1 - 7.4 4.6 9.3 8.5 4.4 6.5 1.0 1 0 0 1 1 1 0 Menin Macoilin PF09726.4 ETO33315.1 - 7.4 4.7 10.4 7.3 4.7 7.2 1.0 1 0 0 1 1 1 0 Transmembrane protein AvrE PF11725.3 ETO33315.1 - 8.6 3.2 11.3 8.7 3.2 7.8 1.0 1 0 0 1 1 1 0 Pathogenicity factor Asp-B-Hydro_N PF05279.6 ETO33315.1 - 9 6.0 14.3 9.9 5.9 9.9 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Pkinase PF00069.20 ETO33317.1 - 1.7e-56 191.2 0.1 2.8e-56 190.5 0.0 1.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO33317.1 - 1.4e-22 79.9 0.0 2.7e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO33317.1 - 4.8e-06 25.7 0.0 1.4 7.7 0.0 3.1 2 1 1 3 3 3 3 Kinase-like WD40 PF00400.27 ETO33318.1 - 4.6e-67 219.6 22.1 6.4e-12 44.8 0.6 6.8 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO33318.1 - 1.6e-13 49.6 4.6 0.0018 16.5 0.2 5.8 3 1 3 6 6 6 6 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO33318.1 - 0.00068 18.4 12.7 0.047 12.4 0.1 4.3 1 1 0 2 2 2 1 Nup133 N terminal like DUF851 PF05867.6 ETO33318.1 - 0.0011 18.2 0.0 0.67 9.1 0.0 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF851) RED_C PF07807.6 ETO33318.1 - 0.11 12.6 0.1 39 4.4 0.0 3.6 4 0 0 4 4 4 0 RED-like protein C-terminal region WD40 PF00400.27 ETO33319.1 - 1.6e-22 78.4 15.6 2e-08 33.8 0.4 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO33319.1 - 0.0034 15.5 1.5 0.38 8.8 0.5 2.5 1 1 1 2 2 2 2 Nucleoporin Nup120/160 TPR_12 PF13424.1 ETO33322.1 - 1.7e-39 133.5 10.8 3.7e-21 74.8 0.6 3.0 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO33322.1 - 1.5e-23 80.6 2.0 2.7e-08 32.9 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO33322.1 - 3.9e-21 73.7 22.5 1.8e-08 33.6 2.1 3.6 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO33322.1 - 3.7e-20 71.3 7.9 6.2e-11 41.7 0.3 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 ETO33322.1 - 2.4e-18 64.4 12.5 7.6e-06 25.4 1.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO33322.1 - 3.5e-17 60.8 21.4 1.1e-06 27.9 1.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO33322.1 - 4.1e-17 61.5 0.2 1.5e-05 24.7 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO33322.1 - 2.2e-06 28.1 0.2 0.12 13.0 0.1 2.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO33322.1 - 3.6e-06 26.7 8.1 0.1 12.8 0.2 4.9 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO33322.1 - 7.1e-06 26.1 3.3 0.018 15.5 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat SNAP PF14938.1 ETO33322.1 - 3.4e-05 23.1 2.7 9.7e-05 21.6 1.9 1.6 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_14 PF13428.1 ETO33322.1 - 9.4e-05 22.7 0.0 1.4 9.7 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat Sel1 PF08238.7 ETO33322.1 - 0.00014 22.3 9.3 1.2 9.9 0.5 3.5 3 0 0 3 3 3 3 Sel1 repeat DUF2225 PF09986.4 ETO33322.1 - 0.00033 20.1 3.9 0.0056 16.1 0.1 2.4 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) Apc3 PF12895.2 ETO33322.1 - 0.00041 20.4 4.2 0.54 10.4 0.0 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 ATP-synt_E_2 PF08112.6 ETO33322.1 - 0.0094 15.9 9.4 0.36 10.9 0.8 3.8 3 0 0 3 3 3 1 ATP synthase epsilon subunit SHNi-TPR PF10516.4 ETO33322.1 - 0.016 14.4 1.3 0.17 11.1 0.1 2.8 3 0 0 3 3 3 0 SHNi-TPR MIT PF04212.13 ETO33322.1 - 0.019 14.8 10.0 0.86 9.5 0.3 3.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain OEP PF02321.13 ETO33322.1 - 0.036 13.6 0.1 4.5 6.8 0.1 2.4 2 0 0 2 2 2 0 Outer membrane efflux protein TPR_3 PF07720.7 ETO33322.1 - 0.063 13.0 8.5 0.11 12.3 0.5 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Ubiq-assoc PF09145.5 ETO33322.1 - 2.8 7.8 8.1 8.3 6.3 0.1 3.6 4 0 0 4 4 4 0 Ubiquitin-associated DUF3450 PF11932.3 ETO33322.1 - 3.7 6.7 6.2 5.6 6.1 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) WD40 PF00400.27 ETO33323.1 - 2.5e-37 125.4 18.8 2e-10 40.1 0.0 7.1 6 1 1 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO33323.1 - 0.00021 19.5 6.2 0.82 7.7 0.1 3.9 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Ole-e-6 PF09253.5 ETO33323.1 - 0.22 11.2 2.1 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Pollen allergen ole e 6 Apt1 PF10351.4 ETO33325.1 - 0.65 8.7 10.9 0.47 9.2 6.4 1.6 2 0 0 2 2 2 0 Golgi-body localisation protein domain THOC7 PF05615.8 ETO33326.1 - 2.1e-06 28.0 13.4 2.1e-06 28.0 9.3 1.9 1 1 1 2 2 2 1 Tho complex subunit 7 zf-C4H2 PF10146.4 ETO33326.1 - 0.021 14.8 12.5 0.027 14.4 8.7 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein DUF2197 PF09963.4 ETO33326.1 - 0.056 13.4 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) YlbE PF14003.1 ETO33326.1 - 0.5 10.4 3.8 3.1 7.9 0.2 3.0 1 1 2 3 3 3 0 YlbE-like protein DUF3573 PF12097.3 ETO33326.1 - 0.59 8.6 5.2 0.66 8.5 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Fib_alpha PF08702.5 ETO33326.1 - 1.2 9.2 13.1 0.39 10.8 6.8 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Flagellar_rod PF05149.7 ETO33326.1 - 1.5 7.9 20.9 0.56 9.3 6.3 2.2 2 0 0 2 2 2 0 Paraflagellar rod protein DUF948 PF06103.6 ETO33326.1 - 5.4 6.9 6.0 1.7 8.5 0.4 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) LMBR1 PF04791.11 ETO33326.1 - 6.9 5.1 7.3 9.4 4.6 5.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein LRR_8 PF13855.1 ETO33328.1 - 5.5e-06 26.0 12.5 0.014 15.1 0.1 3.7 2 1 1 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 ETO33328.1 - 0.0054 16.6 17.4 0.45 10.7 0.1 5.7 6 0 0 6 6 6 2 Leucine Rich repeat LRR_4 PF12799.2 ETO33328.1 - 0.28 10.8 9.5 4.3 7.0 0.1 3.7 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) SMN PF06003.7 ETO33328.1 - 4.7 6.2 6.3 7.2 5.6 0.0 2.1 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) ubiquitin PF00240.18 ETO33329.1 - 8.3e-33 111.6 8.8 3.8e-16 58.2 0.3 4.1 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 ETO33329.1 - 1.4e-14 53.5 3.1 6.7e-08 32.1 0.1 3.7 4 0 0 4 4 4 2 Ubiquitin-2 like Rad60 SUMO-like DUF366 PF04017.7 ETO33329.1 - 0.017 14.3 0.0 1.4 8.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF366) Ubiquitin_2 PF14560.1 ETO33329.1 - 0.036 14.3 4.3 3.8 7.8 0.1 4.2 4 1 0 4 4 4 0 Ubiquitin-like domain DUF2407 PF10302.4 ETO33329.1 - 0.086 13.0 0.1 0.22 11.7 0.0 1.8 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain TPR_12 PF13424.1 ETO33330.1 - 8.7e-91 297.9 13.0 8.1e-21 73.7 0.2 5.0 3 1 3 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETO33330.1 - 4.1e-49 164.0 27.5 2.4e-12 46.3 0.9 5.0 2 1 4 6 6 6 6 TPR repeat TPR_1 PF00515.23 ETO33330.1 - 8.7e-45 148.5 34.4 3.8e-08 32.5 0.2 7.9 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_7 PF13176.1 ETO33330.1 - 1.3e-40 133.9 3.1 2.3e-06 26.9 0.0 7.3 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETO33330.1 - 2e-38 127.3 34.5 1.7e-08 33.6 0.3 8.2 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.12 ETO33330.1 - 5.1e-36 119.6 19.5 2.4e-05 23.8 0.0 8.0 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_10 PF13374.1 ETO33330.1 - 2.8e-33 112.8 0.0 4.4e-07 29.6 0.0 6.3 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.1 ETO33330.1 - 4.5e-15 54.5 8.8 0.065 13.4 0.0 8.4 8 2 1 9 9 8 3 Tetratricopeptide repeat MIT PF04212.13 ETO33330.1 - 2.7e-11 43.2 13.6 0.073 12.9 0.1 6.4 5 1 1 6 6 6 3 MIT (microtubule interacting and transport) domain TPR_14 PF13428.1 ETO33330.1 - 5e-11 42.2 0.0 3.4 8.5 0.0 6.9 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO33330.1 - 5.4e-11 42.1 2.4 0.85 10.2 0.0 7.2 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO33330.1 - 4.3e-08 33.6 0.0 0.18 12.5 0.0 5.5 2 1 5 7 7 7 3 Tetratricopeptide repeat DUF2225 PF09986.4 ETO33330.1 - 2.6e-07 30.3 9.6 0.011 15.2 0.2 4.8 1 1 3 4 4 4 3 Uncharacterized protein conserved in bacteria (DUF2225) SHNi-TPR PF10516.4 ETO33330.1 - 1.1e-06 27.7 0.6 1.2 8.4 0.0 5.5 5 1 0 5 5 5 1 SHNi-TPR Apc3 PF12895.2 ETO33330.1 - 1.2e-06 28.5 14.9 0.00023 21.2 0.6 4.3 2 2 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 ETO33330.1 - 7.6e-05 22.4 19.3 0.0091 15.7 0.1 6.7 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO33330.1 - 0.00041 20.6 0.2 6.3 7.2 0.0 4.3 3 3 0 3 3 3 0 Tetratricopeptide repeat mit_SMPDase PF14724.1 ETO33330.1 - 0.00061 17.7 0.5 0.043 11.6 0.1 2.1 1 1 1 2 2 2 2 Mitochondrial-associated sphingomyelin phosphodiesterase RPN7 PF10602.4 ETO33330.1 - 0.00099 18.5 11.1 0.73 9.1 0.1 4.1 1 1 3 4 4 4 3 26S proteasome subunit RPN7 Sel1 PF08238.7 ETO33330.1 - 0.0015 19.1 9.1 4.4 8.0 0.0 6.3 7 0 0 7 7 7 1 Sel1 repeat SPOB_ab PF14682.1 ETO33330.1 - 0.02 14.6 0.5 5.9 6.7 0.1 2.8 2 0 0 2 2 2 0 Sporulation initiation phospho-transferase B, C-terminal Foie-gras_1 PF11817.3 ETO33330.1 - 0.19 11.1 1.4 2.7 7.4 0.1 2.8 3 0 0 3 3 3 0 Foie gras liver health family 1 CathepsinC_exc PF08773.6 ETO33330.1 - 0.25 11.5 3.3 0.57 10.3 0.1 3.0 3 1 0 4 4 3 0 Cathepsin C exclusion domain NSF PF02071.15 ETO33330.1 - 0.37 11.5 13.5 1.3e+02 3.9 0.1 6.8 6 0 0 6 6 6 0 Aromatic-di-Alanine (AdAR) repeat WD40 PF00400.27 ETO33332.1 - 4.7e-84 273.5 19.0 1.7e-13 49.9 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO33332.1 - 2.1e-09 36.1 8.9 0.0075 14.4 0.0 4.9 1 1 4 5 5 5 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO33332.1 - 6.9e-07 27.8 4.9 0.072 11.3 0.0 3.4 1 1 4 5 5 5 4 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO33332.1 - 3e-06 26.2 12.0 0.085 11.5 0.2 4.6 1 1 2 4 4 4 4 Nup133 N terminal like PQQ_2 PF13360.1 ETO33332.1 - 1.2e-05 24.8 1.0 0.00034 20.1 0.1 3.0 1 1 1 2 2 2 1 PQQ-like domain Hira PF07569.6 ETO33332.1 - 0.00022 20.4 0.1 1.3 8.1 0.0 3.9 3 1 1 4 4 4 1 TUP1-like enhancer of split Coatomer_WDAD PF04053.9 ETO33332.1 - 0.00075 18.4 1.0 0.29 9.8 0.0 2.2 1 1 1 2 2 2 2 Coatomer WD associated region Nbas_N PF15492.1 ETO33332.1 - 0.00093 18.3 1.5 1.6 7.7 0.1 3.6 1 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal SGL PF08450.7 ETO33332.1 - 0.0021 17.4 1.6 1.1 8.5 0.0 2.9 1 1 1 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region DPPIV_N PF00930.16 ETO33332.1 - 0.0025 16.4 0.1 2.9 6.3 0.0 3.5 1 1 2 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region OapA PF04225.7 ETO33332.1 - 0.0055 16.5 0.1 3 7.7 0.0 3.1 2 1 0 2 2 2 1 Opacity-associated protein A LysM-like domain Me-amine-dh_H PF06433.6 ETO33332.1 - 0.0072 15.0 0.0 0.33 9.5 0.0 2.8 1 1 2 3 3 3 1 Methylamine dehydrogenase heavy chain (MADH) DUF1258 PF06869.7 ETO33332.1 - 0.058 12.4 0.8 1.8 7.5 0.2 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF1258) SusE PF14292.1 ETO33332.1 - 0.087 12.6 0.0 3.3 7.5 0.0 2.5 2 0 0 2 2 2 0 SusE outer membrane protein Proteasome_A_N PF10584.4 ETO33332.1 - 0.2 11.0 8.3 31 4.0 0.0 5.0 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature PD40 PF07676.7 ETO33332.1 - 1.4 8.6 19.0 16 5.2 0.0 6.4 8 0 0 8 8 7 0 WD40-like Beta Propeller Repeat Kinesin-relat_1 PF12711.2 ETO33333.1 - 0.0088 16.4 7.0 0.047 14.0 4.8 2.1 1 1 0 1 1 1 1 Kinesin motor MCR_D PF02505.9 ETO33333.1 - 0.031 13.8 2.2 0.037 13.6 1.6 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein D DUF3610 PF12272.3 ETO33333.1 - 0.071 12.7 3.8 0.095 12.3 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3610) FlaC_arch PF05377.6 ETO33333.1 - 0.26 11.1 12.4 0.058 13.2 4.7 2.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DSPc PF00782.15 ETO33333.1 - 1.3 8.5 5.5 1.9 8.1 3.7 1.4 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Lipoprotein_20 PF13942.1 ETO33333.1 - 2.1 7.8 8.4 2.6 7.5 5.9 1.1 1 0 0 1 1 1 0 YfhG lipoprotein TPR_11 PF13414.1 ETO33334.1 - 0.00037 20.0 0.0 0.0019 17.8 0.0 2.2 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 ETO33334.1 - 0.0061 16.3 0.5 0.44 10.5 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat ELFV_dehydrog PF00208.16 ETO33335.1 - 8e-81 271.2 1.4 9.3e-81 270.9 1.0 1.0 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 ETO33335.1 - 6.6e-20 71.0 0.0 3.1e-19 68.8 0.0 2.1 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DUF4083 PF13314.1 ETO33336.1 - 0.0064 16.2 0.2 0.052 13.3 0.0 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4083) Neur_chan_memb PF02932.11 ETO33336.1 - 0.035 14.0 3.4 0.057 13.2 2.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4551 PF15087.1 ETO33336.1 - 0.17 10.2 6.8 0.2 9.9 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Zip PF02535.17 ETO33336.1 - 0.48 9.3 3.7 0.91 8.4 2.6 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter Pex16 PF08610.5 ETO33336.1 - 3.5 6.5 7.9 6.7 5.6 5.5 1.5 1 1 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF1131 PF06572.7 ETO33338.1 - 0.093 12.1 0.1 0.2 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1131) zf-C2H2 PF00096.21 ETO33338.1 - 0.11 12.8 0.2 0.62 10.5 0.0 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF1289 PF06945.8 ETO33338.1 - 0.12 11.8 0.3 0.43 10.0 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) DUF1690 PF07956.6 ETO33341.1 - 0.012 15.6 9.4 0.012 15.6 6.5 1.7 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) Rad10 PF03834.9 ETO33341.1 - 0.013 15.1 0.1 0.039 13.6 0.0 1.8 1 0 0 1 1 1 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Apolipoprotein PF01442.13 ETO33341.1 - 0.034 13.6 2.8 0.13 11.7 1.9 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Phg_2220_C PF09524.5 ETO33341.1 - 0.1 12.6 3.5 1.6 8.7 0.0 2.5 2 0 0 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) PIP49_N PF14875.1 ETO33341.1 - 0.23 11.1 3.5 0.84 9.2 0.4 2.5 1 1 1 2 2 2 0 N-term cysteine-rich ER, FAM69 Z1 PF10593.4 ETO33341.1 - 7.9 5.6 10.3 6.2 5.9 5.2 2.1 1 1 1 2 2 2 0 Z1 domain UCH PF00443.24 ETO33342.1 - 6.8e-09 35.2 2.0 7e-09 35.1 1.4 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO33342.1 - 0.00025 20.5 0.4 0.00033 20.1 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2582 PF10771.4 ETO33342.1 - 0.061 13.1 0.4 0.13 12.1 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2582) YlqD PF11068.3 ETO33344.1 - 0.063 13.3 1.4 0.083 12.9 1.0 1.1 1 0 0 1 1 1 0 YlqD protein RNase_H2-Ydr279 PF09468.5 ETO33344.1 - 0.063 12.4 5.0 0.08 12.1 3.5 1.0 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Cys_rich_CPCC PF14206.1 ETO33344.1 - 0.12 11.9 0.6 0.18 11.4 0.4 1.5 1 1 0 1 1 1 0 Cysteine-rich CPCC Plant_NMP1 PF06694.6 ETO33344.1 - 0.16 10.8 1.2 0.17 10.8 0.8 1.0 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) Arif-1 PF06770.6 ETO33346.1 - 0.41 9.9 2.9 0.47 9.7 2.0 1.2 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) Esterase PF00756.15 ETO33348.1 - 1.4e-18 67.2 0.0 1.8e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Putative esterase DUF4176 PF13780.1 ETO33348.1 - 0.082 12.6 0.6 0.18 11.5 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4176) ADH_N PF08240.7 ETO33350.1 - 1.2e-23 82.9 0.3 8.8e-21 73.7 0.5 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETO33350.1 - 0.0041 16.6 0.0 0.008 15.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase EFP PF01132.15 ETO33350.1 - 0.0072 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain ThiF PF00899.16 ETO33350.1 - 0.12 12.1 0.3 0.25 11.1 0.2 1.5 1 0 0 1 1 1 0 ThiF family ADH_zinc_N PF00107.21 ETO33351.1 - 1.7e-12 47.0 0.1 2.1e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETO33351.1 - 0.0003 21.6 0.0 0.00034 21.4 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TruD PF01142.13 ETO33352.1 - 5.6e-34 117.4 1.2 3.7e-20 71.9 0.1 3.7 3 1 1 4 4 4 2 tRNA pseudouridine synthase D (TruD) EcKinase PF02958.15 ETO33353.1 - 1e-08 34.7 1.5 0.00019 20.7 0.3 2.6 2 1 0 2 2 2 2 Ecdysteroid kinase DUF1679 PF07914.6 ETO33353.1 - 8.3e-07 27.9 1.4 3.6e-06 25.8 1.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) APH PF01636.18 ETO33353.1 - 0.0013 18.5 0.0 0.019 14.6 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Sirohm_synth_C PF14823.1 ETO33353.1 - 0.31 10.3 2.7 0.78 9.0 1.9 1.7 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal ODV-E18 PF10717.4 ETO33354.1 - 0.15 11.5 0.5 0.16 11.3 0.4 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 WD40 PF00400.27 ETO33355.1 - 4.2e-83 270.5 21.8 1.6e-12 46.7 0.1 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO33355.1 - 4.8e-07 28.8 8.6 0.44 9.2 0.1 6.2 1 1 5 6 6 6 3 Nup133 N terminal like Nup160 PF11715.3 ETO33355.1 - 1e-06 27.1 9.1 0.29 9.2 0.0 5.5 1 1 3 5 5 5 3 Nucleoporin Nup120/160 Kelch_2 PF07646.10 ETO33355.1 - 1.1e-06 28.1 0.4 0.029 14.1 0.0 4.9 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 ETO33355.1 - 1.4e-06 28.2 2.6 0.32 11.2 0.1 5.4 6 0 0 6 6 5 2 Kelch motif Kelch_4 PF13418.1 ETO33355.1 - 1.5e-06 27.8 0.9 0.011 15.5 0.0 4.6 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO33355.1 - 4.6e-06 26.0 4.6 0.0013 18.2 0.3 4.2 4 0 0 4 4 4 1 Kelch motif Cytochrom_D1 PF02239.11 ETO33355.1 - 8.6e-05 20.9 0.4 0.0078 14.5 0.1 3.2 1 1 2 4 4 4 2 Cytochrome D1 heme domain Kelch_3 PF13415.1 ETO33355.1 - 0.00012 22.1 0.1 0.0076 16.4 0.0 3.4 3 0 0 3 3 3 1 Galactose oxidase, central domain PQQ_2 PF13360.1 ETO33355.1 - 0.00066 19.2 0.0 0.0014 18.1 0.0 1.6 1 0 0 1 1 1 1 PQQ-like domain PD40 PF07676.7 ETO33355.1 - 0.0015 18.1 2.1 11 5.7 0.0 3.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 ETO33355.1 - 0.018 14.1 1.0 1.9 7.5 0.0 3.2 1 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Kelch_5 PF13854.1 ETO33355.1 - 0.045 13.7 0.4 1.1 9.3 0.0 3.4 3 0 0 3 3 3 0 Kelch motif Proteasome_A_N PF10584.4 ETO33355.1 - 0.76 9.1 5.0 6.9 6.0 0.0 3.4 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 ETO33356.1 - 6.7e-17 60.6 5.6 1e-11 44.2 0.4 2.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO33356.1 - 0.00085 17.5 1.1 0.17 9.9 0.1 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO33356.1 - 0.0056 15.4 1.1 0.014 14.1 0.7 1.7 1 1 0 1 1 1 1 Nup133 N terminal like Pkinase PF00069.20 ETO33357.1 - 1.2e-45 155.7 0.5 4.2e-39 134.2 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO33357.1 - 3.6e-21 75.3 0.1 2.2e-20 72.8 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 ETO33357.1 - 0.0011 18.0 1.0 0.0021 17.1 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETO33357.1 - 0.0032 16.4 0.0 0.0072 15.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 ETO33357.1 - 0.094 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family ABC_membrane PF00664.18 ETO33358.1 - 3.4e-17 62.7 3.6 3.4e-17 62.7 2.5 3.0 2 1 1 3 3 3 2 ABC transporter transmembrane region DUF445 PF04286.7 ETO33358.1 - 0.053 13.0 0.9 0.12 11.9 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF445) ETRAMP PF09716.5 ETO33358.1 - 0.4 10.6 1.7 2.6 8.0 0.0 3.3 4 0 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) DUF106 PF01956.11 ETO33358.1 - 3 7.3 12.7 0.21 11.1 1.3 3.7 4 1 0 4 4 4 0 Integral membrane protein DUF106 Ank PF00023.25 ETO33359.1 - 3e-49 162.4 6.4 1.8e-08 33.7 0.0 9.2 9 0 0 9 9 9 9 Ankyrin repeat Ank_2 PF12796.2 ETO33359.1 - 2.7e-48 162.2 7.0 1.7e-14 53.8 0.0 5.2 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO33359.1 - 5.1e-36 121.8 1.7 3.5e-08 33.4 0.0 6.7 4 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO33359.1 - 2.6e-34 116.9 4.5 2.4e-07 31.0 0.0 7.7 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO33359.1 - 1.1e-32 108.7 7.3 4.4e-05 23.3 0.0 9.2 9 0 0 9 9 9 6 Ankyrin repeat PI3_PI4_kinase PF00454.22 ETO33361.1 - 2.6e-21 76.1 3.1 1.7e-19 70.2 2.1 3.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase ABM PF03992.11 ETO33362.1 - 6.2e-17 61.3 0.0 1.1e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF3443 PF11925.3 ETO33362.1 - 0.11 11.1 0.1 0.18 10.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3443) F-box PF00646.28 ETO33363.1 - 0.006 16.2 0.1 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 ETO33363.1 - 0.0092 15.6 0.0 0.023 14.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like Fe_dep_repr_C PF02742.10 ETO33363.1 - 0.065 12.9 0.3 0.16 11.7 0.2 1.6 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain Peptidase_S49_N PF08496.5 ETO33364.1 - 0.081 12.7 5.8 0.098 12.4 4.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3987 PF13148.1 ETO33364.1 - 3.8 5.9 6.4 3.6 6.0 4.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) WD40 PF00400.27 ETO33365.1 - 6.4e-71 231.9 35.5 1e-12 47.4 0.1 7.8 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO33365.1 - 5.5e-09 34.7 0.4 0.053 11.6 0.0 5.0 1 1 3 4 4 4 3 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO33365.1 - 6e-05 23.3 2.0 6e-05 23.3 1.4 2.1 2 0 0 2 2 2 1 TRAF-type zinc finger BBS2_Mid PF14783.1 ETO33365.1 - 0.016 14.9 0.1 18 5.1 0.0 3.8 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region MCM PF00493.18 ETO33366.1 - 3.7e-130 433.5 0.3 5.3e-130 433.0 0.2 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 ETO33366.1 - 3.5e-19 69.4 0.4 2.2e-18 66.9 0.0 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 ETO33366.1 - 2.6e-06 26.7 0.0 1.6e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Mg_chelatase_2 PF13335.1 ETO33366.1 - 0.0049 17.2 1.1 0.017 15.5 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 ETO33366.1 - 0.0055 16.3 0.0 0.014 15.0 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETO33366.1 - 0.035 13.8 0.0 0.085 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 ETO33367.1 - 7.8e-15 55.3 1.4 7.4e-14 52.2 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.1 ETO33367.1 - 0.022 14.7 0.1 0.033 14.1 0.1 1.3 1 0 0 1 1 1 0 AAA ATPase domain 60KD_IMP PF02096.15 ETO33368.1 - 0.06 13.0 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 60Kd inner membrane protein Paramyxo_P PF01806.12 ETO33368.1 - 0.33 10.1 2.8 0.53 9.4 1.9 1.3 1 0 0 1 1 1 0 Paramyxovirinae P phosphoprotein C-terminal region Dynein_heavy PF03028.10 ETO33369.1 - 1.4e-16 59.7 0.3 1.7e-16 59.4 0.2 1.1 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor DUF2201_N PF13203.1 ETO33369.1 - 0.081 12.0 0.0 0.099 11.7 0.0 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain EntA_Immun PF08951.5 ETO33369.1 - 0.19 11.9 2.3 6.7 6.9 0.4 2.9 3 0 0 3 3 3 0 Enterocin A Immunity TauD PF02668.11 ETO33370.1 - 1.2e-31 110.2 0.0 1.6e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Vfa1 PF08432.5 ETO33371.1 - 0.098 12.6 16.3 0.12 12.3 11.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SpoIIIAH PF12685.2 ETO33371.1 - 0.13 11.7 12.2 0.17 11.3 8.5 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein SlyX PF04102.7 ETO33371.1 - 0.13 12.6 6.9 0.45 10.9 4.8 1.9 1 1 0 1 1 1 0 SlyX DUF3005 PF11448.3 ETO33371.1 - 0.14 11.7 1.5 0.25 10.9 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3005) Dak2 PF02734.12 ETO33371.1 - 0.15 11.7 0.3 0.19 11.3 0.2 1.2 1 0 0 1 1 1 0 DAK2 domain MRP-S31 PF15433.1 ETO33371.1 - 0.23 10.8 10.8 0.28 10.5 7.5 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF935 PF06074.7 ETO33371.1 - 0.3 9.7 5.0 0.37 9.4 3.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Cnd3 PF12719.2 ETO33371.1 - 0.64 8.9 4.4 0.85 8.5 3.1 1.1 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain DUF3552 PF12072.3 ETO33371.1 - 0.67 9.1 15.0 0.82 8.8 10.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) CCDC-167 PF15188.1 ETO33371.1 - 0.94 9.4 5.8 0.43 10.5 1.9 1.9 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 V_ATPase_I PF01496.14 ETO33371.1 - 0.96 7.2 7.2 1.1 7.0 5.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 ETO33371.1 - 2.3 7.7 6.4 2.9 7.4 4.4 1.2 1 0 0 1 1 1 0 IncA protein UPF0184 PF03670.8 ETO33371.1 - 4.4 7.5 8.9 5.2 7.3 5.9 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) GBP_C PF02841.9 ETO33371.1 - 7.3 5.6 13.8 9.7 5.2 9.6 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF4407 PF14362.1 ETO33371.1 - 8.6 5.2 9.2 11 4.8 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HSP70 PF00012.15 ETO33371.1 - 9.6 3.9 12.4 11 3.7 8.6 1.0 1 0 0 1 1 1 0 Hsp70 protein FSH1 PF03959.8 ETO33372.1 - 1.1e-44 152.4 0.0 1.2e-44 152.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 ETO33372.1 - 3.9e-05 23.4 0.0 6.3e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETO33372.1 - 0.00016 21.6 0.0 0.015 15.2 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 ETO33372.1 - 0.084 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_1 PF00561.15 ETO33372.1 - 0.12 11.8 0.0 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Imm39 PF15600.1 ETO33374.1 - 0.0024 17.7 2.0 0.1 12.4 0.2 2.3 1 1 1 2 2 2 2 Immunity protein 39 SAM_2 PF07647.12 ETO33374.1 - 0.091 12.6 0.1 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Pro_isomerase PF00160.16 ETO33375.1 - 1.6e-41 142.0 0.3 1.9e-41 141.8 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Endotoxin_N PF03945.9 ETO33376.1 - 0.042 13.2 15.9 0.0083 15.5 7.4 2.1 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain Condensin2nSMC PF12422.3 ETO33376.1 - 0.17 11.6 2.4 0.31 10.7 1.7 1.4 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit APG6 PF04111.7 ETO33376.1 - 0.63 9.0 17.5 1.1 8.1 12.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 ETO33376.1 - 1 7.1 9.8 1.5 6.5 6.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Dna2 PF08696.6 ETO33376.1 - 1.5 8.0 8.6 2.7 7.2 6.0 1.3 1 0 0 1 1 1 0 DNA replication factor Dna2 DUF342 PF03961.8 ETO33376.1 - 2.3 6.5 12.1 4.9 5.4 8.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) HEAT_2 PF13646.1 ETO33377.1 - 4e-06 27.0 0.0 0.065 13.5 0.0 3.0 3 1 1 4 4 4 3 HEAT repeats TIP120 PF08623.5 ETO33377.1 - 4.1e-05 23.2 1.2 0.11 12.0 0.0 3.7 2 1 0 3 3 3 2 TATA-binding protein interacting (TIP20) HEAT PF02985.17 ETO33377.1 - 6.2e-05 22.7 0.1 0.1 12.7 0.0 4.4 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 ETO33377.1 - 0.0028 18.0 0.0 3.5 8.2 0.0 4.3 5 0 0 5 5 5 1 HEAT-like repeat NACHT PF05729.7 ETO33378.1 - 6.7e-08 32.3 0.0 1.5e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain FACT-Spt16_Nlob PF14826.1 ETO33378.1 - 0.078 12.5 0.1 0.25 10.8 0.0 1.8 2 0 0 2 2 2 0 FACT complex subunit SPT16 N-terminal lobe domain DUF2937 PF11157.3 ETO33379.1 - 0.014 14.7 0.5 0.016 14.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) MRP-S28 PF10213.4 ETO33379.1 - 0.024 14.7 2.1 0.044 13.8 0.2 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit protein DUF904 PF06005.7 ETO33379.1 - 5.1 7.4 8.0 12 6.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF904) RNB PF00773.14 ETO33380.1 - 4.4e-65 220.0 1.2 6e-65 219.6 0.8 1.2 1 0 0 1 1 1 1 RNB domain Ribosomal_S19 PF00203.16 ETO33381.1 - 1.1e-23 82.6 1.1 2.1e-23 81.7 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S19 Vps51 PF08700.6 ETO33382.1 - 1.4e-05 24.8 1.1 4.2e-05 23.3 0.0 2.5 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 ETO33382.1 - 0.00017 21.4 0.5 0.0022 17.8 0.1 2.6 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 MFS_1 PF07690.11 ETO33383.1 - 3.8e-17 62.0 25.5 3.8e-17 62.0 17.7 2.7 2 1 1 3 3 3 3 Major Facilitator Superfamily 2OG-FeII_Oxy_3 PF13640.1 ETO33384.1 - 8.3e-11 42.2 0.0 1.6e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 ETO33384.1 - 0.00013 21.5 0.0 0.00027 20.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Oxygenase-NA PF09859.4 ETO33384.1 - 0.0035 16.6 0.0 0.0059 15.9 0.0 1.3 1 0 0 1 1 1 1 Oxygenase, catalysing oxidative methylation of damaged DNA MBT PF02820.13 ETO33385.1 - 0.034 14.0 0.1 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 mbt repeat CBS PF00571.23 ETO33386.1 - 5.3e-06 26.1 0.5 0.2 11.4 0.0 3.3 3 1 0 3 3 3 2 CBS domain Voltage_CLC PF00654.15 ETO33386.1 - 0.00094 18.2 3.2 0.0013 17.8 2.2 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel TPR_12 PF13424.1 ETO33387.1 - 1.1e-121 396.9 35.3 3.9e-24 84.3 0.5 6.2 2 2 4 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.1 ETO33387.1 - 2.8e-59 195.4 0.0 7.3e-09 35.2 0.0 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_1 PF00515.23 ETO33387.1 - 7.8e-58 189.8 50.9 1.2e-08 34.1 0.2 9.6 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_11 PF13414.1 ETO33387.1 - 8.6e-58 191.9 24.0 1.7e-14 53.2 0.4 5.7 4 1 1 5 5 5 5 TPR repeat TPR_7 PF13176.1 ETO33387.1 - 1.1e-51 168.5 22.7 1e-08 34.3 0.0 9.7 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 ETO33387.1 - 1e-48 159.3 36.5 8.7e-07 28.3 0.1 9.7 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_8 PF13181.1 ETO33387.1 - 2.1e-42 139.7 66.4 7.7e-09 34.7 0.9 9.7 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_17 PF13431.1 ETO33387.1 - 4e-29 98.3 21.4 0.0025 17.8 0.0 10.6 11 0 0 11 11 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 ETO33387.1 - 2.6e-17 63.0 0.0 0.0014 19.2 0.0 5.7 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO33387.1 - 3.3e-14 52.1 0.0 0.13 12.9 0.0 8.5 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO33387.1 - 6.7e-12 45.0 15.7 0.044 14.2 0.3 8.9 9 0 0 9 9 9 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO33387.1 - 4.6e-11 42.7 29.5 0.0013 18.7 0.5 6.5 1 1 6 7 7 7 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO33387.1 - 8.5e-07 29.2 7.0 1.1 9.6 0.2 6.6 1 1 8 9 9 9 2 Tetratricopeptide repeat PPR PF01535.15 ETO33387.1 - 2.3e-05 24.0 26.4 0.067 13.2 0.1 9.1 9 0 0 9 9 9 1 PPR repeat Ten1_2 PF15490.1 ETO33387.1 - 8.5e-05 22.1 0.2 18 4.9 0.0 5.9 1 1 5 7 7 7 0 Telomere-capping, CST complex subunit SHNi-TPR PF10516.4 ETO33387.1 - 0.0048 16.1 7.2 14 5.0 0.0 6.9 8 0 0 8 8 8 0 SHNi-TPR AhpC-TSA PF00578.16 ETO33387.1 - 0.0062 16.2 0.2 0.034 13.8 0.1 2.2 1 0 0 1 1 1 1 AhpC/TSA family TPR_3 PF07720.7 ETO33387.1 - 0.014 15.1 42.4 0.039 13.7 0.3 8.2 9 0 0 9 9 9 0 Tetratricopeptide repeat DUF3568 PF12092.3 ETO33387.1 - 0.015 15.0 16.6 6.6 6.4 0.0 7.1 2 1 5 7 7 7 0 Protein of unknown function (DUF3568) TPR_21 PF09976.4 ETO33387.1 - 0.029 14.3 0.3 2.2 8.2 0.0 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 ETO33387.1 - 0.033 14.0 29.2 0.31 10.9 0.2 7.7 8 1 1 9 9 8 0 MIT (microtubule interacting and transport) domain TPR_9 PF13371.1 ETO33387.1 - 0.12 12.2 0.0 4.8 7.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.7 ETO33387.1 - 0.26 11.9 18.9 4.5 8.0 0.0 6.7 7 0 0 7 7 6 0 Sel1 repeat DUF1796 PF08795.5 ETO33387.1 - 0.34 10.5 4.9 0.28 10.8 0.3 2.8 3 0 0 3 3 3 0 Putative papain-like cysteine peptidase (DUF1796) Kelch_4 PF13418.1 ETO33388.1 - 0.036 13.8 0.7 0.25 11.1 0.0 2.8 2 1 0 2 2 2 0 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO33388.1 - 0.058 13.1 0.4 4 7.3 0.1 2.8 2 0 0 2 2 2 0 Kelch motif TPR_12 PF13424.1 ETO33389.1 - 2.2e-09 37.1 0.0 5.2e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat Peptidase_C14 PF00656.17 ETO33389.1 - 9.1e-08 32.0 3.5 1.6e-07 31.3 1.4 2.1 2 1 0 2 2 2 1 Caspase domain TPR_1 PF00515.23 ETO33389.1 - 1.4e-06 27.6 3.0 2.6e-05 23.6 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO33389.1 - 7e-06 25.4 0.0 7.8e-05 22.1 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO33389.1 - 7.6e-06 25.4 0.0 0.0051 16.6 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO33389.1 - 2.7e-05 23.6 0.6 0.00016 21.2 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO33389.1 - 0.00016 21.2 0.1 0.014 15.0 0.1 2.5 2 0 0 2 2 2 1 TPR repeat TPR_3 PF07720.7 ETO33389.1 - 0.02 14.6 10.0 0.46 10.3 0.2 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 ETO33389.1 - 0.027 14.3 0.0 0.16 11.9 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO33389.1 - 0.055 13.9 0.1 0.38 11.3 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.15 ETO33389.1 - 0.2 11.7 1.0 11 6.2 0.0 3.6 3 0 0 3 3 3 0 PPR repeat FDX-ACB PF03147.9 ETO33390.1 - 0.074 13.2 0.1 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Ferredoxin-fold anticodon binding domain CDC45 PF02724.9 ETO33391.1 - 0.4 8.6 4.3 0.73 7.8 3.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.6 ETO33391.1 - 1.3 6.7 5.3 2 6.1 3.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sigma70_ner PF04546.8 ETO33391.1 - 1.3 8.5 7.1 1.9 8.0 3.8 2.1 3 0 0 3 3 3 0 Sigma-70, non-essential region Pkinase PF00069.20 ETO33392.1 - 7e-15 54.8 0.0 9.2e-15 54.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO33392.1 - 0.00014 21.0 0.0 0.00019 20.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Asn_synthase PF00733.16 ETO33394.1 - 1.7e-33 116.2 0.0 3.5e-33 115.1 0.0 1.5 2 0 0 2 2 2 1 Asparagine synthase GATase_7 PF13537.1 ETO33394.1 - 2.1e-32 111.4 0.0 4.4e-32 110.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 ETO33394.1 - 4.2e-25 88.2 0.0 9.4e-25 87.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 ETO33394.1 - 5.1e-13 48.7 0.3 1.3e-11 44.2 0.0 2.7 2 1 1 3 3 3 1 Aluminium induced protein GATase_2 PF00310.16 ETO33394.1 - 3.3e-07 29.3 0.0 2.6e-05 23.0 0.0 2.8 2 1 1 3 3 3 1 Glutamine amidotransferases class-II QueC PF06508.8 ETO33394.1 - 0.004 16.4 0.0 0.0077 15.5 0.0 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 ETO33394.1 - 0.077 11.5 0.0 0.14 10.6 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase NAD_synthase PF02540.12 ETO33394.1 - 0.085 11.7 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 NAD synthase NACHT PF05729.7 ETO33395.1 - 4.5e-07 29.6 0.0 9.2e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETO33395.1 - 0.0023 18.0 0.1 0.031 14.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 ETO33395.1 - 0.0042 15.9 2.0 0.0095 14.8 0.0 2.3 2 1 0 2 2 2 1 NB-ARC domain AAA_19 PF13245.1 ETO33395.1 - 0.0056 16.3 0.0 0.0096 15.6 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 ETO33395.1 - 0.011 15.7 0.0 0.025 14.5 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain DRY_EERY PF09750.4 ETO33395.1 - 0.046 13.8 3.7 0.052 13.6 1.9 1.6 1 1 0 1 1 1 0 Alternative splicing regulator FtsK_SpoIIIE PF01580.13 ETO33395.1 - 0.051 13.0 0.1 0.24 10.8 0.0 2.0 2 1 0 2 2 2 0 FtsK/SpoIIIE family AAA_25 PF13481.1 ETO33395.1 - 0.064 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 ETO33395.1 - 0.35 10.6 5.5 0.69 9.6 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function DUF87 ABC_tran PF00005.22 ETO33395.1 - 0.35 11.1 4.3 0.43 10.8 0.0 2.7 1 1 1 2 2 2 0 ABC transporter AAA_18 PF13238.1 ETO33395.1 - 0.45 10.8 7.9 1.3 9.3 0.0 2.7 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 ETO33395.1 - 1.1 9.4 5.4 1.5 9.0 0.1 3.2 1 1 2 3 3 3 0 RNA helicase RVT_thumb PF06817.9 ETO33396.1 - 0.036 13.6 0.1 0.073 12.6 0.1 1.5 1 0 0 1 1 1 0 Reverse transcriptase thumb domain Menin PF05053.8 ETO33397.1 - 0.15 10.2 6.7 0.19 9.8 4.7 1.2 1 0 0 1 1 1 0 Menin PGA2 PF07543.7 ETO33397.1 - 2.7 7.7 16.6 0.075 12.8 5.4 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 HSP90 PF00183.13 ETO33398.1 - 1.3e-234 779.5 34.5 9.1e-233 773.4 23.9 2.0 1 1 0 1 1 1 1 Hsp90 protein DUF399 PF04187.8 ETO33398.1 - 0.14 11.6 1.9 0.17 11.3 0.1 2.0 3 0 0 3 3 3 0 Protein of unknown function, DUF399 Nucleoplasmin PF03066.10 ETO33398.1 - 4.1 6.9 20.5 2.3 7.7 7.0 2.9 3 0 0 3 3 3 0 Nucleoplasmin DJ-1_PfpI PF01965.19 ETO33399.1 - 1.8e-23 82.6 0.1 2.3e-23 82.2 0.1 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 ETO33399.1 - 1.1e-14 54.0 0.0 1.3e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase TPT PF03151.11 ETO33400.1 - 0.00047 19.8 9.8 0.00047 19.8 6.8 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family DUF4187 PF13821.1 ETO33400.1 - 1.4 8.5 4.1 4 7.1 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) EamA PF00892.15 ETO33400.1 - 1.9 8.5 21.1 1.1 9.3 5.0 2.9 1 1 2 3 3 3 0 EamA-like transporter family DUF3810 PF12725.2 ETO33400.1 - 2.9 6.7 7.9 1.5 7.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Cullin PF00888.17 ETO33401.1 - 6.2e-27 94.3 12.5 1.8e-18 66.4 1.1 2.7 3 0 0 3 3 3 2 Cullin family Phage-A118_gp45 PF10653.4 ETO33401.1 - 0.04 13.7 0.1 0.2 11.5 0.0 2.1 2 0 0 2 2 2 0 Protein gp45 of Bacteriophage A118 CMV_1a PF12467.3 ETO33402.1 - 0.37 11.1 8.4 0.21 11.9 3.4 2.3 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family Serpin PF00079.15 ETO33403.1 - 4.6e-13 49.0 0.0 5.4e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.15 ETO33404.1 - 8.7e-13 48.1 1.7 1e-12 47.9 1.2 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) eIF-3c_N PF05470.7 ETO33404.1 - 0.0016 16.6 1.1 0.0019 16.3 0.8 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Sigma70_ner PF04546.8 ETO33404.1 - 0.023 14.3 8.3 0.04 13.5 5.8 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 ETO33404.1 - 0.059 11.4 4.3 0.066 11.2 3.0 1.2 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.11 ETO33404.1 - 0.064 12.2 4.9 0.092 11.7 3.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Tim54 PF11711.3 ETO33404.1 - 0.13 10.8 3.6 0.17 10.4 2.5 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2956 PF11169.3 ETO33404.1 - 0.13 12.2 3.9 0.084 12.8 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Vfa1 PF08432.5 ETO33404.1 - 0.14 12.1 11.7 0.1 12.6 5.5 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Peptidase_S49_N PF08496.5 ETO33404.1 - 1.3 8.8 5.8 0.36 10.6 1.9 1.6 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF1510 PF07423.6 ETO33404.1 - 3.5 6.9 13.4 5.6 6.2 9.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) IncA PF04156.9 ETO33404.1 - 4.1 6.9 8.4 6.4 6.3 5.8 1.4 1 0 0 1 1 1 0 IncA protein DUF2457 PF10446.4 ETO33404.1 - 4.5 5.8 12.7 6.8 5.2 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RNA_pol_Rpc4 PF05132.9 ETO33404.1 - 8.6 6.3 7.1 16 5.5 4.9 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Kelch_6 PF13964.1 ETO33405.1 - 4.8e-06 26.4 0.4 9.2e-05 22.4 0.0 2.6 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.20 ETO33405.1 - 6e-06 25.6 0.3 0.0016 17.9 0.0 2.6 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 ETO33405.1 - 1e-05 25.2 0.2 0.00013 21.6 0.1 2.5 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO33405.1 - 0.00023 21.2 0.2 0.0011 19.0 0.0 2.2 2 0 0 2 2 2 1 Galactose oxidase, central domain DUF2217 PF10265.4 ETO33405.1 - 0.0031 16.3 1.3 0.0051 15.6 0.9 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2217) DUF3633 PF12315.3 ETO33405.1 - 2.4 7.3 6.3 1.2 8.4 2.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3633) WD40 PF00400.27 ETO33406.1 - 2.6e-07 30.2 5.2 8.4e-07 28.6 0.6 3.1 3 1 0 3 3 3 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO33406.1 - 0.0015 16.7 0.0 0.0018 16.4 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 7TM_GPCR_Srw PF10324.4 ETO33407.1 - 0.036 13.1 0.1 0.062 12.4 0.0 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw ATP-synt_8 PF00895.15 ETO33407.1 - 0.1 12.7 3.8 0.25 11.5 2.6 1.7 1 0 0 1 1 1 0 ATP synthase protein 8 Mrr_N PF14338.1 ETO33407.1 - 0.12 12.4 1.0 0.17 11.9 0.2 1.6 2 0 0 2 2 2 0 Mrr N-terminal domain LRR_4 PF12799.2 ETO33408.1 - 1.8e-16 59.3 18.5 3.2e-07 29.8 1.1 5.0 3 2 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO33408.1 - 3.9e-08 32.9 7.3 0.001 18.8 0.1 3.8 3 1 0 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 ETO33408.1 - 3.5e-07 29.3 18.0 0.017 15.0 0.1 6.9 6 3 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.1 ETO33408.1 - 0.3 11.2 10.8 1.5 9.1 0.0 4.4 4 2 1 5 5 5 0 Leucine Rich repeat LRR_7 PF13504.1 ETO33408.1 - 1.5 9.3 15.9 3.7 8.1 0.0 5.3 6 0 0 6 6 6 0 Leucine rich repeat LRR_1 PF00560.28 ETO33409.1 - 0.73 10.0 14.6 1.7 9.0 0.1 6.1 7 1 0 7 7 7 0 Leucine Rich Repeat DUF4239 PF14023.1 ETO33410.1 - 0.13 11.6 1.8 0.16 11.2 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) DUF2207 PF09972.4 ETO33410.1 - 0.7 8.4 3.4 0.8 8.2 2.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TPR_11 PF13414.1 ETO33411.1 - 1.1e-11 44.1 4.1 7.9e-05 22.2 0.0 3.1 3 0 0 3 3 3 3 TPR repeat TPR_14 PF13428.1 ETO33411.1 - 1.6e-09 37.5 0.1 0.033 14.8 0.0 4.1 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO33411.1 - 5.4e-07 29.3 7.6 0.023 14.8 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO33411.1 - 7.6e-07 28.5 0.6 0.17 11.8 0.0 4.4 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETO33411.1 - 6.2e-06 25.9 0.2 0.00012 21.8 0.4 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO33411.1 - 1e-05 25.7 0.0 0.23 11.8 0.0 2.8 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO33411.1 - 1.7e-05 24.1 0.9 0.0041 16.6 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO33411.1 - 2.5e-05 24.8 0.1 0.24 12.1 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO33411.1 - 8.7e-05 22.3 1.6 0.0072 16.1 0.0 3.0 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.1 ETO33411.1 - 0.00035 20.4 4.9 0.12 12.3 0.1 3.4 1 1 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO33411.1 - 0.0051 16.5 0.6 2 8.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO33411.1 - 0.0091 15.7 2.5 0.53 10.1 0.0 3.7 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO33411.1 - 0.012 15.7 6.2 1.1 9.3 0.0 3.0 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETO33411.1 - 0.021 15.2 2.1 2.1 9.0 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat FlbT PF07378.6 ETO33411.1 - 0.045 13.6 0.1 6.1 6.7 0.1 2.2 2 0 0 2 2 2 0 Flagellar protein FlbT Fijivirus_P9-2 PF06837.6 ETO33412.1 - 0.051 12.7 9.0 0.027 13.6 3.2 2.0 2 0 0 2 2 2 0 Fijivirus P9-2 protein DUF4011 PF13195.1 ETO33412.1 - 0.92 9.5 14.9 0.088 12.8 6.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) DUF4407 PF14362.1 ETO33412.1 - 9.1 5.1 14.0 15 4.4 9.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SIP1 PF04938.7 ETO33413.1 - 0.39 10.0 9.8 0.49 9.7 6.8 1.1 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) DnaI_N PF07319.6 ETO33413.1 - 1.3 9.3 10.0 1.4 9.1 6.1 1.7 1 1 0 1 1 1 0 Primosomal protein DnaI N-terminus DcpS_C PF11969.3 ETO33413.1 - 1.4 9.1 9.4 1.4 9.1 0.2 2.2 1 1 1 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding RNA_pol_Rpb1_5 PF04998.12 ETO33413.1 - 6.2 5.9 7.0 7.4 5.7 4.8 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF4555 PF15093.1 ETO33414.1 - 0.064 12.1 0.0 0.099 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4555) CitMHS PF03600.11 ETO33415.1 - 0.38 9.2 4.6 1.1 7.7 1.0 2.1 2 0 0 2 2 2 0 Citrate transporter zf-RING_5 PF14634.1 ETO33416.1 - 0.011 15.4 0.2 0.023 14.4 0.1 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 ETO33416.1 - 0.013 15.2 0.2 0.031 13.9 0.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.1 ETO33416.1 - 0.016 15.0 0.3 0.032 14.0 0.2 1.4 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.1 ETO33416.1 - 0.019 14.4 0.1 0.038 13.5 0.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.20 ETO33416.1 - 0.019 14.5 0.3 0.049 13.3 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 ETO33416.1 - 0.1 12.1 0.6 0.24 11.0 0.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Ion_trans PF00520.26 ETO33417.1 - 4.1e-13 49.0 9.7 2.6e-12 46.4 5.6 2.4 2 0 0 2 2 2 1 Ion transport protein PKD_channel PF08016.7 ETO33417.1 - 1.3e-09 36.9 5.9 2.6e-09 36.0 4.1 1.4 1 0 0 1 1 1 1 Polycystin cation channel TraP PF07296.6 ETO33417.1 - 0.52 9.2 3.4 0.32 9.9 0.1 2.2 2 0 0 2 2 2 0 TraP protein DUF489 PF04356.7 ETO33418.1 - 1.3 8.5 6.0 0.81 9.2 0.9 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF489) tRNA-synt_2d PF01409.15 ETO33420.1 - 1.1e-16 60.7 0.0 2.3e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 ETO33420.1 - 9.1e-14 51.4 0.1 2e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Drf_FH1 PF06346.7 ETO33422.1 - 0.0013 18.3 0.5 0.0018 17.7 0.3 1.1 1 0 0 1 1 1 1 Formin Homology Region 1 Plasmodium_Vir PF05795.6 ETO33422.1 - 0.2 10.8 1.2 0.43 9.7 0.1 1.8 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Kelch_6 PF13964.1 ETO33424.1 - 8.9e-10 38.3 1.2 3.7e-05 23.6 0.1 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO33424.1 - 8.6e-05 22.4 0.3 0.046 13.6 0.1 4.0 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.1 ETO33424.1 - 0.011 15.5 0.8 0.22 11.3 0.0 3.2 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO33424.1 - 0.13 11.7 1.5 2.6 7.6 0.0 3.3 4 0 0 4 4 4 0 Kelch motif Menin PF05053.8 ETO33424.1 - 0.37 8.9 3.5 0.52 8.4 2.5 1.1 1 0 0 1 1 1 0 Menin WD40 PF00400.27 ETO33425.1 - 1e-68 224.9 17.9 5.3e-12 45.1 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO33425.1 - 1.1e-05 23.8 5.0 0.13 10.3 0.1 4.4 1 1 4 5 5 5 3 Nucleoporin Nup120/160 PD40 PF07676.7 ETO33425.1 - 0.00041 19.9 1.6 4.9 6.9 0.0 5.2 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 ETO33425.1 - 0.0018 17.4 4.0 7.5 5.5 0.0 4.1 2 2 2 4 4 4 2 Protein of unknown function (DUF1258) DPPIV_N PF00930.16 ETO33425.1 - 0.0026 16.3 0.1 0.37 9.3 0.0 3.4 1 1 2 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nucleoporin_N PF08801.6 ETO33425.1 - 0.0037 16.0 4.1 0.24 10.0 0.5 4.2 1 1 2 3 3 3 2 Nup133 N terminal like NYD-SP28_assoc PF14775.1 ETO33425.1 - 0.012 15.2 0.7 6.3 6.5 0.0 4.3 6 0 0 6 6 6 0 Sperm tail C-terminal domain Proteasome_A_N PF10584.4 ETO33425.1 - 0.025 13.9 2.8 15 4.9 0.0 4.5 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 ETO33426.1 - 2.4e-47 157.1 26.5 2.7e-10 39.7 0.4 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO33426.1 - 1.1e-06 27.0 4.3 0.0075 14.4 0.1 4.0 2 1 1 3 3 3 3 Nucleoporin Nup120/160 SASP PF00269.15 ETO33426.1 - 0.28 11.0 1.3 3 7.7 0.1 2.2 2 0 0 2 2 2 0 Small, acid-soluble spore proteins, alpha/beta type Kelch_2 PF07646.10 ETO33426.1 - 3.6 7.4 7.0 7.8 6.4 0.1 4.1 5 0 0 5 5 5 0 Kelch motif EF1G PF00647.14 ETO33427.1 - 0.11 12.2 0.4 3.3 7.4 0.1 2.4 2 1 0 2 2 2 0 Elongation factor 1 gamma, conserved domain DUF3573 PF12097.3 ETO33427.1 - 0.29 9.7 4.5 0.2 10.2 1.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) AUX_IAA PF02309.11 ETO33428.1 - 0.7 9.6 6.5 0.99 9.1 4.5 1.2 1 0 0 1 1 1 0 AUX/IAA family CAP_GLY PF01302.20 ETO33429.1 - 1.7e-16 59.6 0.8 3.5e-16 58.6 0.1 1.8 2 0 0 2 2 2 1 CAP-Gly domain CD45 PF12567.3 ETO33430.1 - 0.026 14.3 0.9 0.053 13.3 0.6 1.6 1 0 0 1 1 1 0 Leukocyte receptor CD45 WD40 PF00400.27 ETO33431.1 - 1e-62 205.9 19.7 1.9e-11 43.3 0.0 7.5 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO33431.1 - 7.5e-06 24.3 5.3 0.66 8.0 0.0 4.7 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO33431.1 - 0.00014 20.3 0.5 0.21 9.8 0.2 2.2 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO33431.1 - 0.004 16.2 0.5 4.3 6.3 0.0 3.6 1 1 3 4 4 4 1 Neuroblastoma-amplified sequence, N terminal NodS PF05401.6 ETO33431.1 - 0.039 13.3 0.2 2.9 7.2 0.0 2.8 2 1 0 2 2 2 0 Nodulation protein S (NodS) DPPIV_N PF00930.16 ETO33431.1 - 0.054 12.0 0.1 3.5 6.1 0.0 2.9 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Hira PF07569.6 ETO33431.1 - 0.13 11.4 2.9 1.3 8.1 0.1 3.3 3 1 1 4 4 4 0 TUP1-like enhancer of split PD40 PF07676.7 ETO33431.1 - 0.76 9.5 4.1 9.3 6.0 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO33431.1 - 0.97 8.1 10.4 0.63 8.7 1.9 3.3 1 1 2 3 3 3 0 Nup133 N terminal like Ras PF00071.17 ETO33432.1 - 5.8e-33 113.5 0.1 1.2e-32 112.5 0.0 1.5 1 1 1 2 2 2 1 Ras family Miro PF08477.8 ETO33432.1 - 2.1e-14 54.0 0.3 4e-14 53.1 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO33432.1 - 1.2e-07 31.1 0.1 1.7e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.13 ETO33432.1 - 0.003 16.8 0.1 0.012 14.9 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B Arch_ATPase PF01637.13 ETO33432.1 - 0.0064 16.2 0.1 0.0091 15.7 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase MMR_HSR1 PF01926.18 ETO33432.1 - 0.021 14.7 0.4 0.041 13.8 0.2 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase DEAD PF00270.24 ETO33433.1 - 5.7e-22 77.9 0.0 1.4e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 ETO33433.1 - 0.001 18.9 0.2 0.048 13.4 0.0 3.0 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit T2SE PF00437.15 ETO33433.1 - 0.0078 15.1 0.0 0.014 14.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Zot PF05707.7 ETO33433.1 - 0.033 13.6 0.0 0.075 12.4 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DUF1631 PF07793.6 ETO33433.1 - 0.042 11.9 0.2 0.077 11.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) GTP_EFTU PF00009.22 ETO33433.1 - 0.068 12.5 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain KTI12 PF08433.5 ETO33433.1 - 0.15 11.2 3.4 1.2 8.2 0.9 2.3 1 1 1 2 2 2 0 Chromatin associated protein KTI12 DUF4168 PF13767.1 ETO33433.1 - 0.38 11.4 0.0 0.38 11.4 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4168) RNR_N PF08343.5 ETO33435.1 - 0.33 10.7 3.1 4.6 7.1 0.2 2.2 1 1 0 2 2 2 0 Ribonucleotide reductase N-terminal ABC_tran PF00005.22 ETO33436.1 - 1.2e-19 71.0 0.1 1.9e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 ETO33436.1 - 6e-06 25.6 0.3 8.2e-06 25.2 0.2 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 ETO33436.1 - 0.0076 16.1 3.1 0.025 14.5 0.7 2.5 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.10 ETO33436.1 - 0.008 15.8 0.3 0.012 15.3 0.2 1.3 1 0 0 1 1 1 1 NTPase DDE_5 PF13546.1 ETO33436.1 - 0.031 13.1 0.0 0.055 12.3 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF1764 PF08576.5 ETO33438.1 - 0.007 17.1 0.8 0.015 16.0 0.6 1.5 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) PID PF00640.18 ETO33438.1 - 0.31 11.0 2.8 2.7 7.9 0.1 2.2 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) WD40 PF00400.27 ETO33439.1 - 3.1e-05 23.6 0.3 0.00027 20.7 0.1 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF3563 PF12086.3 ETO33440.1 - 0.05 13.3 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3563) LRR_4 PF12799.2 ETO33442.1 - 4.2e-14 51.7 16.2 8.6e-05 22.0 1.4 4.9 4 0 0 4 4 4 4 Leucine Rich repeats (2 copies) Alpha_kinase PF02816.13 ETO33442.1 - 8.2e-11 41.9 4.4 9.1e-09 35.2 3.1 2.8 1 1 0 1 1 1 1 Alpha-kinase family LRR_8 PF13855.1 ETO33442.1 - 4.9e-07 29.4 9.9 1.3e-05 24.8 2.5 4.5 3 1 1 4 4 4 2 Leucine rich repeat DUF912 PF06024.7 ETO33442.1 - 0.27 11.3 0.0 0.27 11.3 0.0 3.3 4 0 0 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) LRR_7 PF13504.1 ETO33442.1 - 1.2 9.6 8.0 82 4.1 0.1 5.4 4 0 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 ETO33442.1 - 2.2 8.6 13.5 61 4.1 0.2 5.5 3 1 2 5 5 5 0 Leucine Rich repeat Exo_endo_phos_2 PF14529.1 ETO33443.1 - 1.3e-06 28.0 0.3 2.1e-06 27.3 0.2 1.4 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase WD40 PF00400.27 ETO33444.1 - 1.1e-34 117.0 7.5 4.6e-11 42.1 0.0 5.8 5 1 0 5 5 5 4 WD domain, G-beta repeat FANCI_HD1 PF14679.1 ETO33445.1 - 0.019 14.6 0.1 0.039 13.6 0.1 1.5 1 0 0 1 1 1 0 FANCI helical domain 1 DAGAT PF03982.8 ETO33445.1 - 0.044 12.4 0.1 0.061 12.0 0.1 1.2 1 0 0 1 1 1 0 Diacylglycerol acyltransferase UPF0254 PF06787.6 ETO33445.1 - 0.1 12.1 1.0 0.13 11.7 0.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0254) DUF2052 PF09747.4 ETO33445.1 - 0.2 11.5 10.3 0.24 11.3 7.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) BRF1 PF07741.8 ETO33445.1 - 0.5 10.6 17.5 0.38 11.0 9.4 2.1 1 1 1 2 2 2 0 Brf1-like TBP-binding domain WD40 PF00400.27 ETO33446.1 - 3e-22 77.6 15.7 2.3e-09 36.7 0.6 4.8 4 1 0 4 4 4 3 WD domain, G-beta repeat Cellulase-like PF12876.2 ETO33446.1 - 0.021 15.2 0.3 1.7 9.1 0.1 3.0 2 1 0 2 2 2 0 Sugar-binding cellulase-like LisH PF08513.6 ETO33447.1 - 4.6e-05 23.0 0.4 8.6e-05 22.1 0.3 1.5 1 0 0 1 1 1 1 LisH P4Ha_N PF08336.6 ETO33447.1 - 0.02 14.7 1.3 0.51 10.1 0.1 2.2 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Mit_KHE1 PF10173.4 ETO33447.1 - 0.28 11.0 3.1 0.42 10.4 2.1 1.4 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related TraE PF05309.6 ETO33448.1 - 0.023 13.8 0.0 0.053 12.6 0.0 1.6 1 0 0 1 1 1 0 TraE protein 7TMR-DISM_7TM PF07695.6 ETO33448.1 - 6.6 6.3 19.9 0.65 9.6 9.9 1.9 2 0 0 2 2 2 0 7TM diverse intracellular signalling Macoilin PF09726.4 ETO33449.1 - 0.38 8.9 12.0 0.43 8.7 8.3 1.0 1 0 0 1 1 1 0 Transmembrane protein MRP-L46 PF11788.3 ETO33449.1 - 0.81 10.3 7.1 1.1 9.9 4.9 1.1 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 FLO_LFY PF01698.11 ETO33449.1 - 2 7.1 10.4 2.2 7.0 7.2 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Ycf1 PF05758.7 ETO33449.1 - 4 5.0 7.7 3.9 5.0 5.4 1.0 1 0 0 1 1 1 0 Ycf1 Cwf_Cwc_15 PF04889.7 ETO33449.1 - 4.5 6.9 23.1 5.5 6.6 16.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1510 PF07423.6 ETO33449.1 - 5.3 6.3 19.3 6.6 6.0 13.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Neur_chan_memb PF02932.11 ETO33449.1 - 8.3 6.2 7.2 10 5.9 5.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAM_2 PF07647.12 ETO33450.1 - 0.1 12.4 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) HSP90 PF00183.13 ETO33451.1 - 3.1e-43 147.9 11.6 3.2e-39 134.7 3.8 2.6 2 1 0 2 2 2 2 Hsp90 protein DUF399 PF04187.8 ETO33451.1 - 0.16 11.4 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF399 T_Ag_DNA_bind PF02217.11 ETO33452.1 - 0.032 14.6 0.0 0.21 11.9 0.0 2.0 1 1 1 2 2 2 0 Origin of replication binding protein FlaG PF03646.10 ETO33452.1 - 0.12 12.5 0.3 0.19 11.9 0.2 1.3 1 0 0 1 1 1 0 FlaG protein TF_Zn_Ribbon PF08271.7 ETO33453.1 - 0.003 16.8 2.5 0.014 14.6 1.7 2.1 1 0 0 1 1 1 1 TFIIB zinc-binding ZZ PF00569.12 ETO33453.1 - 0.035 13.6 5.0 0.081 12.4 3.4 1.6 1 0 0 1 1 1 0 Zinc finger, ZZ type zf-ribbon_3 PF13248.1 ETO33453.1 - 0.3 10.3 9.7 0.038 13.2 2.9 2.1 1 1 1 2 2 2 0 zinc-ribbon domain TPR_12 PF13424.1 ETO33455.1 - 7.5e-26 89.8 10.0 2.8e-12 46.3 1.8 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO33455.1 - 5.4e-15 54.7 31.7 2.5e-07 30.2 2.1 3.9 1 1 3 4 4 4 4 TPR repeat TPR_1 PF00515.23 ETO33455.1 - 9.3e-11 40.8 25.8 0.0091 15.5 0.2 6.0 5 1 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETO33455.1 - 2.9e-10 39.2 20.1 0.064 13.2 0.2 5.7 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.1 ETO33455.1 - 6e-09 35.0 4.4 0.31 10.9 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO33455.1 - 1.4e-07 31.2 0.0 0.23 11.4 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO33455.1 - 9.1e-06 25.0 24.3 0.12 12.1 0.2 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO33455.1 - 0.00046 20.5 1.1 33 5.4 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO33455.1 - 0.0017 18.7 10.4 0.89 10.1 0.0 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat DUF2225 PF09986.4 ETO33455.1 - 0.0076 15.7 9.8 0.018 14.5 3.4 2.8 1 1 2 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_17 PF13431.1 ETO33455.1 - 0.023 14.8 1.4 0.72 10.1 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.7 ETO33455.1 - 0.35 11.5 12.5 0.5 11.0 0.1 3.8 4 0 0 4 4 3 0 Sel1 repeat TPR_16 PF13432.1 ETO33455.1 - 0.36 11.5 4.5 62 4.4 0.5 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 ETO33455.1 - 0.79 9.6 12.5 9.5 6.1 0.1 4.0 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain WD40 PF00400.27 ETO33456.1 - 1.5e-25 88.0 7.8 1.1e-09 37.8 0.2 3.9 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO33456.1 - 0.00023 19.4 0.3 0.12 10.4 0.1 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PUB PF09409.5 ETO33457.1 - 0.0019 17.9 1.0 0.023 14.4 0.7 2.6 1 1 0 1 1 1 1 PUB domain PSRP-3_Ycf65 PF04839.8 ETO33457.1 - 0.011 15.7 1.2 0.027 14.4 0.8 1.6 1 0 0 1 1 1 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) Cys_rich_VLP PF14194.1 ETO33458.1 - 0.13 12.0 0.9 0.25 11.1 0.6 1.5 1 0 0 1 1 1 0 Cysteine-rich VLP TPR_12 PF13424.1 ETO33459.1 - 3.7e-09 36.3 0.7 8.5e-09 35.2 0.4 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO33459.1 - 0.064 12.9 0.1 0.17 11.5 0.1 1.7 1 0 0 1 1 1 0 TPR repeat GNAT_acetyltran PF12746.2 ETO33460.1 - 0.11 11.2 1.5 0.16 10.7 1.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase DUF702 PF05142.7 ETO33461.1 - 0.16 12.1 1.3 0.27 11.3 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF702) MIP-T3 PF10243.4 ETO33462.1 - 3 6.2 47.2 3.4 6.0 32.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 WD40 PF00400.27 ETO33464.1 - 4.3e-66 216.6 14.4 7.9e-11 41.4 0.0 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO33464.1 - 1.1e-08 33.7 2.2 0.37 8.8 0.0 5.8 1 1 4 6 6 6 5 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO33464.1 - 0.0017 18.2 0.0 2 8.3 0.0 3.2 2 1 0 2 2 2 2 Domain of unknown function (DUF3601) CCDC144C PF14915.1 ETO33464.1 - 0.02 13.7 2.7 0.028 13.3 1.9 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region C2 PF00168.25 ETO33466.1 - 5.3e-05 22.9 0.0 0.00017 21.3 0.0 1.8 1 1 1 2 2 2 1 C2 domain IBR PF01485.16 ETO33467.1 - 5.8e-19 67.7 39.5 5e-12 45.5 9.5 3.9 4 0 0 4 4 4 2 IBR domain DUF4263 PF14082.1 ETO33467.1 - 0.02 14.8 0.0 0.057 13.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4263) zf-C3HC4 PF00097.20 ETO33467.1 - 0.11 12.1 0.1 0.11 12.1 0.1 5.6 5 1 0 5 5 5 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO33467.1 - 1.3 8.9 31.5 0.27 11.1 1.4 5.1 4 1 0 4 4 4 0 Ring finger domain WD40 PF00400.27 ETO33469.1 - 5.4e-50 165.5 23.3 2.7e-10 39.7 0.2 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO33469.1 - 1e-11 43.6 4.9 0.00034 18.9 0.0 4.6 1 1 2 4 4 4 4 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO33469.1 - 4.1e-07 30.2 1.8 4.1e-07 30.2 1.3 2.8 2 0 0 2 2 2 1 TRAF-type zinc finger DUF4071 PF13281.1 ETO33469.1 - 0.0047 15.8 4.5 0.008 15.0 3.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4071) MAGSP PF03082.9 ETO33469.1 - 0.022 14.1 6.0 0.038 13.3 4.2 1.4 1 0 0 1 1 1 0 Male accessory gland secretory protein DUF1573 PF07610.6 ETO33470.1 - 0.16 11.5 2.5 0.62 9.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1573) Atrophin-1 PF03154.10 ETO33471.1 - 0.01 14.0 23.5 0.0065 14.6 15.5 1.3 1 1 0 1 1 1 0 Atrophin-1 family TAF4 PF05236.9 ETO33471.1 - 0.16 11.2 22.1 0.014 14.6 12.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family HAUS6_N PF14661.1 ETO33471.1 - 0.67 9.2 14.5 1 8.6 10.1 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Cas_Csy4 PF09618.5 ETO33471.1 - 1.2 8.9 9.5 2.3 7.9 6.6 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) IncA PF04156.9 ETO33471.1 - 3 7.3 18.5 5.9 6.4 12.8 1.5 1 0 0 1 1 1 0 IncA protein RNase_H2-Ydr279 PF09468.5 ETO33471.1 - 5.3 6.1 19.9 0.18 11.0 9.5 1.6 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) V_ATPase_I PF01496.14 ETO33471.1 - 5.6 4.6 10.9 7.3 4.3 7.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Zip PF02535.17 ETO33471.1 - 9.7 5.0 6.4 1.5 7.7 2.0 1.4 2 0 0 2 2 2 0 ZIP Zinc transporter BAF1_ABF1 PF04684.8 ETO33472.1 - 0.13 11.0 2.6 0.15 10.9 1.8 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF2413 PF10310.4 ETO33472.1 - 0.78 8.4 12.1 0.84 8.3 8.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF2217 PF10265.4 ETO33472.1 - 1.7 7.2 5.8 2 7.0 4.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Peptidase_S64 PF08192.6 ETO33472.1 - 5.8 5.1 10.0 6.8 4.8 6.9 1.0 1 0 0 1 1 1 0 Peptidase family S64 Herpes_U26 PF07402.6 ETO33473.1 - 0.017 14.4 0.0 0.019 14.2 0.0 1.1 1 0 0 1 1 1 0 Human herpesvirus U26 protein Mito_fiss_Elm1 PF06258.6 ETO33473.1 - 0.12 11.3 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission ELM1 WD40 PF00400.27 ETO33474.1 - 4.3e-39 131.0 22.1 5.8e-10 38.6 0.5 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO33474.1 - 1.1e-09 37.0 1.0 0.00035 18.8 0.0 3.8 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Lipase_3 PF01764.20 ETO33475.1 - 2.3e-18 66.1 0.0 4.8e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 ETO33475.1 - 0.00053 19.7 0.0 0.00087 19.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 ETO33475.1 - 0.0054 16.1 0.3 0.0096 15.3 0.0 1.5 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 ETO33475.1 - 0.012 15.1 0.0 0.028 13.9 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETO33475.1 - 0.077 12.8 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Actino_peptide PF14408.1 ETO33476.1 - 0.02 14.8 4.6 0.043 13.7 3.2 1.5 1 0 0 1 1 1 0 Ribosomally synthesized peptide in actinomycetes Vfa1 PF08432.5 ETO33476.1 - 0.78 9.7 12.7 1.6 8.7 8.8 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Apc1 PF12859.2 ETO33476.1 - 1.7 8.9 4.5 66 3.7 3.2 2.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 1 Sec62 PF03839.11 ETO33476.1 - 8.6 5.7 7.3 20 4.4 5.0 1.7 1 0 0 1 1 1 0 Translocation protein Sec62 Striatin PF08232.7 ETO33477.1 - 0.0034 17.7 7.7 0.0059 16.9 5.3 1.3 1 0 0 1 1 1 1 Striatin family SlyX PF04102.7 ETO33477.1 - 0.0066 16.7 2.9 0.026 14.8 2.0 2.0 1 0 0 1 1 1 1 SlyX Tropomyosin_1 PF12718.2 ETO33477.1 - 0.0078 16.0 11.1 0.013 15.3 7.7 1.3 1 0 0 1 1 1 1 Tropomyosin like DUF4639 PF15479.1 ETO33477.1 - 0.026 13.2 3.3 0.029 13.0 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4639) FlaC_arch PF05377.6 ETO33477.1 - 0.04 13.8 0.7 0.04 13.8 0.5 2.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) BPL_N PF09825.4 ETO33477.1 - 0.24 10.1 3.3 0.27 9.9 2.3 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal DUF2852 PF11014.3 ETO33477.1 - 0.83 9.6 3.0 2.7 7.9 1.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) Rop-like PF05082.8 ETO33477.1 - 1.4 8.4 4.8 0.29 10.6 0.5 1.9 2 0 0 2 2 2 0 Rop-like IncA PF04156.9 ETO33477.1 - 2.1 7.9 11.9 4.9 6.7 8.2 1.4 1 1 0 1 1 1 0 IncA protein Exonuc_VII_L PF02601.10 ETO33477.1 - 3.4 6.7 12.9 4.2 6.4 9.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Viral_P18 PF04521.8 ETO33477.1 - 8.1 5.9 8.0 0.62 9.5 1.2 2.0 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Ank_3 PF13606.1 ETO33479.1 - 1.4e-06 27.9 0.0 0.029 14.5 0.0 3.8 2 1 1 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 ETO33479.1 - 1.9e-06 28.0 0.0 0.035 14.4 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETO33479.1 - 2e-06 27.3 0.0 0.12 12.2 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 ETO33479.1 - 9.5e-05 22.5 0.2 0.8 10.0 0.1 3.5 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO33479.1 - 0.0025 18.2 0.0 0.6 10.6 0.0 2.9 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Orthopox_A49R PF06489.6 ETO33480.1 - 0.077 12.9 0.4 0.092 12.7 0.3 1.2 1 0 0 1 1 1 0 Orthopoxvirus A49R protein PP1c_bdg PF10488.4 ETO33480.1 - 0.09 11.9 2.0 0.1 11.8 1.4 1.0 1 0 0 1 1 1 0 Phosphatase-1 catalytic subunit binding region Pkinase PF00069.20 ETO33481.1 - 1.8e-45 155.1 0.0 4.4e-41 140.7 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO33481.1 - 3.9e-20 72.0 0.0 8.8e-20 70.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO33481.1 - 0.00089 18.2 0.0 0.0013 17.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like DUF4131 PF13567.1 ETO33481.1 - 0.99 8.7 7.5 5 6.4 5.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) PAE PF03283.8 ETO33482.1 - 3.8e-10 38.9 0.1 4.8e-10 38.6 0.1 1.1 1 0 0 1 1 1 1 Pectinacetylesterase Ycf1 PF05758.7 ETO33483.1 - 0.01 13.6 14.1 0.01 13.6 9.8 1.2 1 0 0 1 1 1 0 Ycf1 Hid1 PF12722.2 ETO33483.1 - 0.28 8.8 17.3 0.34 8.5 12.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FLO_LFY PF01698.11 ETO33483.1 - 1.2 7.9 19.5 1.7 7.3 13.5 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein RR_TM4-6 PF06459.7 ETO33483.1 - 1.5 8.6 18.3 2 8.2 12.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Activator_LAG-3 PF11498.3 ETO33483.1 - 1.6 7.3 28.3 2 7.1 19.6 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 CAF-1_p150 PF11600.3 ETO33483.1 - 1.7 7.9 40.9 2.7 7.3 28.4 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal BTV_NS2 PF04514.7 ETO33483.1 - 2.1 7.1 21.9 2.8 6.7 15.2 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF4557 PF15101.1 ETO33483.1 - 3.4 7.4 18.8 6.1 6.6 13.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Cellulose_synt PF03552.9 ETO33483.1 - 5 5.2 8.5 5.7 5.1 5.9 1.2 1 0 0 1 1 1 0 Cellulose synthase Presenilin PF01080.12 ETO33483.1 - 5.4 5.7 9.3 6.2 5.5 6.4 1.3 1 0 0 1 1 1 0 Presenilin WD40 PF00400.27 ETO33484.1 - 2.8e-67 220.3 26.2 2.5e-11 42.9 0.1 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 ETO33484.1 - 2e-08 32.8 8.6 0.021 12.9 0.0 5.3 2 1 3 5 5 5 4 Nucleoporin Nup120/160 DUF1652 PF07865.6 ETO33484.1 - 1.2e-05 24.7 0.0 2.2 7.9 0.0 4.8 4 1 1 5 5 5 2 Protein of unknown function (DUF1652) Peptidase_C69 PF03577.10 ETO33484.1 - 0.00058 18.8 0.3 1 8.1 0.0 3.8 4 1 0 4 4 4 1 Peptidase family C69 PQQ_2 PF13360.1 ETO33484.1 - 0.0025 17.3 0.1 2.8 7.3 0.0 2.6 1 1 1 2 2 2 2 PQQ-like domain NYD-SP28_assoc PF14775.1 ETO33484.1 - 0.0053 16.4 5.0 15 5.3 0.0 6.4 8 0 0 8 8 8 0 Sperm tail C-terminal domain PD40 PF07676.7 ETO33484.1 - 0.0068 16.0 10.8 1.5 8.5 0.1 4.6 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Mid2 PF04478.7 ETO33484.1 - 0.014 14.7 1.0 2.1 7.7 0.1 3.2 2 1 1 3 3 3 0 Mid2 like cell wall stress sensor SusE PF14292.1 ETO33484.1 - 0.017 14.9 0.1 0.77 9.5 0.0 2.9 3 0 0 3 3 3 0 SusE outer membrane protein F420_ligase PF01996.11 ETO33484.1 - 0.039 13.0 0.0 8.5 5.3 0.0 2.9 2 1 1 3 3 3 0 F420-0:Gamma-glutamyl ligase WD40 PF00400.27 ETO33485.1 - 2.3e-36 122.3 2.0 2e-09 36.9 0.2 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat Pentapeptide PF00805.17 ETO33485.1 - 2.1e-07 30.0 1.3 3.9e-07 29.1 0.9 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO33485.1 - 1.5e-05 24.6 0.3 3.9e-05 23.3 0.2 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Nup160 PF11715.3 ETO33485.1 - 1.9e-05 23.0 1.7 0.94 7.5 0.1 3.2 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Pentapeptide_3 PF13576.1 ETO33485.1 - 9.1e-05 22.2 0.5 0.00023 20.9 0.3 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) CUE PF02845.11 ETO33486.1 - 0.0023 17.3 0.2 0.0084 15.5 0.1 2.0 2 0 0 2 2 2 1 CUE domain RelA_SpoT PF04607.12 ETO33486.1 - 0.1 12.6 0.0 0.1 12.6 0.0 2.5 3 0 0 3 3 3 0 Region found in RelA / SpoT proteins BLVR PF06375.6 ETO33486.1 - 0.17 11.7 8.1 0.31 10.8 5.6 1.5 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) SR-25 PF10500.4 ETO33486.1 - 4.1 6.8 15.5 0.79 9.1 8.3 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Syntaxin_2 PF14523.1 ETO33486.1 - 5.9 6.9 9.3 2.2 8.3 1.9 2.8 2 2 1 3 3 3 0 Syntaxin-like protein 7tm_1 PF00001.16 ETO33488.1 - 0.015 14.4 1.2 0.019 14.1 0.8 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) NMN_transporter PF04973.7 ETO33488.1 - 0.042 13.3 0.2 0.069 12.6 0.1 1.4 1 1 0 1 1 1 0 Nicotinamide mononucleotide transporter TMF_TATA_bd PF12325.3 ETO33489.1 - 0.081 12.6 15.9 1.6 8.4 5.4 3.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4164 PF13747.1 ETO33489.1 - 0.27 11.3 8.0 0.043 13.9 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Med4 PF10018.4 ETO33489.1 - 0.36 10.2 16.2 0.045 13.1 3.5 3.5 2 1 1 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 IncA PF04156.9 ETO33489.1 - 4.9 6.7 20.2 0.018 14.6 5.1 3.0 2 1 1 3 3 3 0 IncA protein DUF3450 PF11932.3 ETO33489.1 - 5.1 6.2 11.7 25 4.0 8.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) ADIP PF11559.3 ETO33489.1 - 5.2 6.9 27.3 0.66 9.8 7.7 3.2 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF2116 PF09889.4 ETO33490.1 - 5.4 6.8 6.3 2.5 7.9 0.2 2.9 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Ycf15 PF10705.4 ETO33491.1 - 0.27 11.3 3.2 0.14 12.2 0.6 1.7 2 0 0 2 2 2 0 Chloroplast protein precursor Ycf15 putative 2OG-FeII_Oxy_4 PF13661.1 ETO33492.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily YfbU PF03887.9 ETO33493.1 - 0.0039 16.7 0.1 3 7.3 0.0 2.5 2 0 0 2 2 2 2 YfbU domain CUE PF02845.11 ETO33494.1 - 0.042 13.3 0.1 0.11 12.0 0.1 1.8 1 0 0 1 1 1 0 CUE domain CW_binding_1 PF01473.15 ETO33494.1 - 0.06 13.4 6.7 0.052 13.6 2.5 2.6 2 0 0 2 2 2 0 Putative cell wall binding repeat DUF3522 PF12036.3 ETO33496.1 - 0.0011 18.8 0.5 0.0011 18.8 0.3 3.5 1 1 1 4 4 4 1 Protein of unknown function (DUF3522) DUF3439 PF11921.3 ETO33496.1 - 0.22 11.2 6.0 0.79 9.4 3.8 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3439) GRIM-19 PF06212.7 ETO33496.1 - 3.6 7.3 5.3 13 5.5 0.1 3.5 2 2 2 4 4 4 0 GRIM-19 protein WD40 PF00400.27 ETO33497.1 - 1.2e-56 186.6 23.3 4.9e-11 42.0 1.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO33497.1 - 6.2e-11 41.1 2.7 0.0086 14.2 0.0 5.4 2 2 2 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO33497.1 - 0.00085 18.1 7.3 0.2 10.3 1.2 3.0 1 1 1 3 3 3 2 Nup133 N terminal like WD40 PF00400.27 ETO33499.1 - 7.3e-15 54.2 0.4 0.00012 21.7 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat EF-hand_7 PF13499.1 ETO33499.1 - 0.091 12.9 0.8 0.47 10.6 0.3 2.4 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_8 PF13833.1 ETO33499.1 - 0.11 12.1 0.0 0.39 10.3 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair Zip PF02535.17 ETO33499.1 - 0.38 9.7 2.1 0.6 9.0 1.5 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter TPR_12 PF13424.1 ETO33500.1 - 8.5e-28 96.1 20.9 9.7e-14 51.0 0.9 4.5 3 1 3 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO33500.1 - 8e-17 59.6 10.6 3.3e-05 23.3 0.1 5.7 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO33500.1 - 6.5e-16 57.7 11.6 2.1e-06 27.2 0.5 3.5 3 0 0 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETO33500.1 - 2e-14 52.4 26.9 7.7e-05 22.1 1.3 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO33500.1 - 3.3e-12 45.3 21.3 0.00067 19.3 0.2 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO33500.1 - 8.3e-11 40.8 16.1 0.0052 16.4 0.3 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO33500.1 - 7.7e-10 38.3 0.5 0.00085 19.1 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO33500.1 - 2.8e-06 27.4 3.3 0.79 10.5 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO33500.1 - 0.0058 16.9 0.7 0.054 13.8 0.0 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat DUF2225 PF09986.4 ETO33500.1 - 0.0078 15.6 11.1 0.28 10.5 0.2 3.3 2 1 1 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_6 PF13174.1 ETO33500.1 - 0.012 15.9 6.8 10 6.8 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO33500.1 - 0.013 14.7 0.0 0.78 9.0 0.0 2.7 2 0 0 2 2 2 0 SHNi-TPR TPR_17 PF13431.1 ETO33500.1 - 0.017 15.2 7.7 0.14 12.4 0.0 3.9 5 0 0 5 5 3 0 Tetratricopeptide repeat DUF4142 PF13628.1 ETO33500.1 - 0.06 13.3 0.3 0.16 12.0 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) TPR_16 PF13432.1 ETO33500.1 - 0.15 12.7 8.5 1.3 9.7 0.3 3.7 3 2 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 ETO33500.1 - 0.44 10.4 10.5 8.4 6.3 0.2 4.2 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain Kelch_6 PF13964.1 ETO33501.1 - 1.7e-08 34.2 5.0 0.00055 20.0 0.2 4.6 3 2 2 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO33501.1 - 2.2e-08 33.7 1.2 3e-05 23.6 0.1 3.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO33501.1 - 5.4e-08 32.2 4.0 1.4e-05 24.5 0.2 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 ETO33501.1 - 1e-06 28.1 8.7 2.1e-06 27.1 0.3 3.7 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.1 ETO33501.1 - 1.9e-06 27.8 1.1 1.3e-05 25.2 0.1 2.8 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO33501.1 - 2.9e-05 23.9 4.1 0.012 15.5 0.2 4.0 4 0 0 4 4 4 2 Kelch motif Pes-10 PF07149.6 ETO33501.1 - 0.036 12.8 1.5 0.05 12.3 1.1 1.1 1 0 0 1 1 1 0 Pes-10 DUF2615 PF11027.3 ETO33501.1 - 0.49 10.3 8.7 3.3 7.6 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2615) DUF2203 PF09969.4 ETO33502.1 - 0.16 12.1 2.4 5.4 7.2 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Mso1_C PF14477.1 ETO33503.1 - 0.014 15.6 2.0 0.041 14.2 0.1 2.5 2 0 0 2 2 2 0 Membrane-polarising domain of Mso1 Mucin PF01456.12 ETO33503.1 - 0.73 9.6 9.4 0.082 12.6 3.4 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein WD40 PF00400.27 ETO33505.1 - 6.7e-68 222.3 15.2 6.8e-13 47.9 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO33505.1 - 0.001 17.9 10.4 1.1 7.9 1.0 4.1 1 1 1 3 3 3 3 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO33505.1 - 0.013 13.7 2.2 2.1 6.5 0.0 3.3 3 1 0 4 4 4 0 Cytochrome D1 heme domain DUF445 PF04286.7 ETO33508.1 - 0.066 12.7 1.2 0.095 12.2 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Mito_carr PF00153.22 ETO33509.1 - 0.003 17.2 8.1 0.37 10.5 0.0 4.2 4 2 1 5 5 5 2 Mitochondrial carrier protein CytB6-F_Fe-S PF08802.5 ETO33509.1 - 2.4 8.2 5.3 5.7 7.0 0.1 3.2 3 0 0 3 3 3 0 Cytochrome B6-F complex Fe-S subunit TPR_12 PF13424.1 ETO33511.1 - 1.3e-20 73.1 0.5 1.4e-09 37.7 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO33511.1 - 1.4e-18 66.2 12.5 1.7e-11 43.5 0.8 2.7 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETO33511.1 - 1.1e-14 53.3 9.4 1.9e-06 27.2 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO33511.1 - 4.1e-14 51.2 13.6 4.7e-07 29.1 0.3 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO33511.1 - 7.3e-14 50.4 8.1 1e-05 25.0 0.2 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO33511.1 - 9.5e-12 43.7 0.4 0.00016 21.2 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO33511.1 - 6.5e-10 38.6 0.0 0.00025 20.8 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF2225 PF09986.4 ETO33511.1 - 2.1e-06 27.3 3.5 5.1e-06 26.1 1.2 2.3 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_17 PF13431.1 ETO33511.1 - 3.2e-05 23.7 0.6 0.44 10.8 0.0 3.3 2 1 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.13 ETO33511.1 - 0.00016 21.5 7.4 0.025 14.4 0.0 3.5 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 ETO33511.1 - 0.00036 20.7 3.6 0.24 11.9 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO33511.1 - 0.00064 20.1 0.0 0.95 10.2 0.0 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO33511.1 - 0.0008 19.4 2.6 0.0092 16.0 0.3 3.2 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 ETO33511.1 - 0.0027 18.3 0.0 0.52 11.0 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat WD40 PF00400.27 ETO33512.1 - 1.1e-59 196.2 25.0 8.9e-11 41.2 0.6 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO33512.1 - 2.1e-13 49.3 2.7 1e-05 23.9 0.1 4.6 1 1 3 4 4 4 4 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO33512.1 - 0.0082 15.5 0.5 0.18 11.1 0.0 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4221) DUF1900 PF08954.6 ETO33512.1 - 0.062 12.8 0.2 3.4 7.1 0.0 3.4 3 1 2 5 5 5 0 Domain of unknown function (DUF1900) Neur_chan_memb PF02932.11 ETO33514.1 - 0.0078 16.1 0.6 0.025 14.4 0.4 1.8 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF4512 PF14975.1 ETO33514.1 - 1.8 9.4 5.1 13 6.7 3.5 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4512) GEMIN8 PF15348.1 ETO33515.1 - 0.069 13.1 9.9 0.1 12.6 6.9 1.3 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DUF4473 PF14747.1 ETO33515.1 - 0.18 12.0 6.7 0.61 10.3 4.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4473) RP-C_C PF11800.3 ETO33515.1 - 0.25 11.0 2.3 0.29 10.8 1.6 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region V_ATPase_I PF01496.14 ETO33515.1 - 0.25 9.1 3.5 0.25 9.1 2.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ResIII PF04851.10 ETO33515.1 - 0.28 10.9 3.8 0.3 10.8 2.6 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Tom37_C PF11801.3 ETO33515.1 - 0.52 10.1 7.9 0.71 9.7 5.5 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain Sec62 PF03839.11 ETO33515.1 - 1 8.7 8.9 1.3 8.3 6.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4228 PF14009.1 ETO33515.1 - 1.1 9.4 8.2 1.3 9.1 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) DUF3435 PF11917.3 ETO33515.1 - 3.1 6.4 7.7 3.4 6.2 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) FAM176 PF14851.1 ETO33515.1 - 5.3 6.7 8.2 7.1 6.2 5.7 1.2 1 0 0 1 1 1 0 FAM176 family Sec23_BS PF08033.7 ETO33516.1 - 6.1e-05 23.4 0.5 0.00018 21.9 0.3 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain PDEase_I PF00233.14 ETO33517.1 - 2.6e-60 204.1 0.0 3e-34 118.8 0.0 2.5 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase ACR_tran PF00873.14 ETO33517.1 - 0.58 7.4 3.1 0.81 7.0 2.2 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family KilA-N PF04383.8 ETO33520.1 - 0.18 11.4 2.4 0.31 10.6 0.0 2.2 2 1 0 2 2 2 0 KilA-N domain WD40 PF00400.27 ETO33521.1 - 1.6e-110 357.4 56.9 2.3e-10 39.9 0.6 16.0 15 1 0 15 15 15 14 WD domain, G-beta repeat NACHT PF05729.7 ETO33521.1 - 3.3e-09 36.6 0.0 7e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO33521.1 - 2.5e-05 24.5 0.1 0.00016 21.9 0.0 2.5 1 0 0 1 1 1 1 AAA domain Pentapeptide PF00805.17 ETO33521.1 - 7.5e-05 21.8 0.5 0.00016 20.7 0.3 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO33521.1 - 0.00024 20.8 0.2 0.00073 19.2 0.1 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA_22 PF13401.1 ETO33521.1 - 0.0014 18.7 0.0 0.0069 16.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain Pentapeptide_3 PF13576.1 ETO33521.1 - 0.0029 17.4 0.8 0.008 16.0 0.6 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA_17 PF13207.1 ETO33521.1 - 0.0057 17.4 0.1 0.051 14.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain PD40 PF07676.7 ETO33521.1 - 0.031 13.9 11.1 14 5.4 0.0 6.8 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat A2L_zn_ribbon PF08792.5 ETO33521.1 - 0.033 13.6 0.2 0.1 12.0 0.1 1.9 1 0 0 1 1 1 0 A2L zinc ribbon domain Mannosyl_trans3 PF11051.3 ETO33522.1 - 2.3e-14 53.4 1.0 2.3e-14 53.4 0.7 2.1 2 1 0 2 2 2 1 Mannosyltransferase putative Glycos_transf_2 PF00535.21 ETO33522.1 - 0.036 13.7 0.1 0.084 12.5 0.1 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 NACHT PF05729.7 ETO33523.1 - 7e-07 29.0 0.0 1.2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETO33523.1 - 0.0018 18.3 0.0 0.0042 17.0 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 ETO33523.1 - 0.0054 15.6 1.0 0.048 12.5 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain AAA_19 PF13245.1 ETO33523.1 - 0.027 14.2 0.0 0.099 12.4 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 ETO33523.1 - 0.079 13.0 0.1 0.3 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 ETO33523.1 - 0.16 12.2 2.7 0.48 10.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.15 ETO33523.1 - 1.3 7.6 12.8 16 4.0 8.8 2.2 1 1 0 1 1 1 0 G-protein alpha subunit V_ATPase_I PF01496.14 ETO33523.1 - 1.6 6.4 6.3 2.1 6.0 4.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Z1 PF10593.4 ETO33523.1 - 3.7 6.6 11.4 2.6 7.1 6.2 1.9 1 1 1 2 2 2 0 Z1 domain ELMO_CED12 PF04727.8 ETO33526.1 - 8e-27 93.8 0.2 1.4e-26 93.0 0.1 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family Rtt102p PF09510.5 ETO33526.1 - 0.28 11.1 4.2 0.74 9.8 0.1 2.6 2 1 0 2 2 2 0 Rtt102p-like transcription regulator protein Piwi PF02171.12 ETO33529.1 - 1.1e-16 60.6 0.0 1.9e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 ETO33529.1 - 5.2e-10 38.7 0.3 1.6e-09 37.1 0.2 1.9 1 0 0 1 1 1 1 PAZ domain DDHD PF02862.12 ETO33529.1 - 0.01 15.6 5.7 0.02 14.7 4.0 1.4 1 0 0 1 1 1 0 DDHD domain RP-C_C PF11800.3 ETO33529.1 - 0.54 9.9 3.9 0.95 9.1 2.7 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region WD40 PF00400.27 ETO33530.1 - 4.3e-28 96.1 4.4 3.8e-08 32.8 0.0 3.2 2 1 1 3 3 3 3 WD domain, G-beta repeat DUF1258 PF06869.7 ETO33530.1 - 0.004 16.2 0.0 0.0061 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) DUF4221 PF13970.1 ETO33530.1 - 0.0073 15.6 0.1 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4221) PRESAN PF09687.5 ETO33530.1 - 0.011 15.7 0.1 0.019 15.0 0.1 1.3 1 0 0 1 1 1 0 Plasmodium RESA N-terminal Nucleoporin_N PF08801.6 ETO33530.1 - 0.028 13.1 1.0 0.051 12.3 0.3 1.8 1 1 0 1 1 1 0 Nup133 N terminal like DUF2457 PF10446.4 ETO33531.1 - 0.036 12.8 16.5 0.048 12.3 11.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.5 ETO33531.1 - 0.099 12.8 12.0 0.22 11.7 8.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GCIP PF13324.1 ETO33531.1 - 0.47 9.6 4.8 0.6 9.2 3.3 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting CDC45 PF02724.9 ETO33531.1 - 0.68 7.8 9.8 0.79 7.6 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 ETO33531.1 - 2.5 7.2 13.0 3.8 6.6 9.0 1.3 1 0 0 1 1 1 0 NOA36 protein DUF3469 PF11952.3 ETO33532.1 - 0.057 13.1 2.7 0.057 13.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3469) HPIH PF13323.1 ETO33532.1 - 2 8.0 9.7 0.17 11.5 2.3 2.4 2 1 1 3 3 3 0 N-terminal domain with HPIH motif GCN5L1 PF06320.8 ETO33533.1 - 1.4e-22 79.8 8.7 1.8e-22 79.4 6.0 1.1 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) FAA_hydrolase_N PF09298.6 ETO33533.1 - 0.0074 16.2 1.9 0.0074 16.2 1.3 1.6 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal Syntaxin-6_N PF09177.6 ETO33533.1 - 0.014 15.8 9.6 0.42 11.0 3.3 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Spc7 PF08317.6 ETO33533.1 - 0.063 11.9 10.5 0.082 11.5 7.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1217 PF06748.7 ETO33533.1 - 0.071 13.1 2.8 0.12 12.4 1.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1217) Rsd_AlgQ PF04353.8 ETO33533.1 - 0.084 12.5 3.1 0.12 12.1 2.2 1.3 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ TFR_dimer PF04253.10 ETO33533.1 - 0.15 11.6 1.7 0.57 9.7 0.3 2.2 2 1 0 2 2 2 0 Transferrin receptor-like dimerisation domain PAPS_reduct PF01507.14 ETO33533.1 - 0.16 11.7 2.0 0.12 12.1 0.4 1.5 1 1 1 2 2 2 0 Phosphoadenosine phosphosulfate reductase family Bacillus_HBL PF05791.6 ETO33533.1 - 0.2 11.0 9.7 0.59 9.4 0.9 2.2 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Seryl_tRNA_N PF02403.17 ETO33533.1 - 0.41 10.6 8.5 1.1 9.3 1.7 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF148 PF02520.12 ETO33533.1 - 0.76 9.5 11.4 1.2 8.9 1.0 3.1 1 1 1 2 2 2 0 Domain of unknown function DUF148 Hrs_helical PF12210.3 ETO33533.1 - 0.79 10.0 3.9 1.6 9.0 0.1 2.4 1 1 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate NPV_P10 PF05531.7 ETO33533.1 - 0.95 9.7 5.7 1.1 9.5 1.2 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Pepsin-I3 PF06394.8 ETO33533.1 - 1.7 8.3 9.2 2 8.1 0.3 2.7 3 0 0 3 3 3 0 Pepsin inhibitor-3-like repeated domain DUF948 PF06103.6 ETO33533.1 - 3.3 7.6 6.2 5.9 6.8 2.2 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Prefoldin PF02996.12 ETO33533.1 - 3.4 7.3 13.9 1.2 8.8 0.4 3.0 2 1 1 3 3 3 0 Prefoldin subunit DUF342 PF03961.8 ETO33533.1 - 8.7 4.6 8.6 17 3.6 6.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) UQ_con PF00179.21 ETO33534.1 - 3.7e-48 162.5 0.0 4.7e-48 162.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 ETO33534.1 - 4.8e-07 29.5 0.0 6.2e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UBA PF00627.26 ETO33534.1 - 0.0002 21.0 0.0 0.00035 20.3 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain UEV PF05743.8 ETO33534.1 - 0.022 14.4 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 UEV domain RGS-like PF09128.6 ETO33534.1 - 0.041 13.3 1.3 1.1 8.7 0.1 2.0 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain RWD PF05773.17 ETO33534.1 - 0.074 12.9 0.1 0.11 12.4 0.0 1.5 1 1 0 1 1 1 0 RWD domain S-methyl_trans PF02574.11 ETO33534.1 - 0.084 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Homocysteine S-methyltransferase DUF1789 PF08748.6 ETO33534.1 - 0.34 11.0 2.7 0.26 11.4 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1789) Exo_endo_phos PF03372.18 ETO33535.1 - 7.9e-12 45.6 0.0 1e-11 45.3 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ras PF00071.17 ETO33537.1 - 0.015 14.6 0.1 0.025 13.9 0.1 1.3 1 0 0 1 1 1 0 Ras family Peptidase_S9 PF00326.16 ETO33540.1 - 0.00013 21.2 0.1 0.00022 20.5 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF202 PF02656.10 ETO33541.1 - 6.7e-07 29.4 4.5 2.1e-06 27.8 3.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF202) VTC PF09359.5 ETO33541.1 - 0.0038 16.2 0.0 0.0065 15.5 0.0 1.4 1 0 0 1 1 1 1 VTC domain DUF1403 PF07183.6 ETO33541.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1403) DUF2207 PF09972.4 ETO33541.1 - 0.19 10.2 0.8 0.25 9.8 0.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2628 PF10947.3 ETO33541.1 - 1.8 8.3 6.1 1.6 8.5 3.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2628) DUF4131 PF13567.1 ETO33541.1 - 5.2 6.4 8.0 10 5.4 5.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) WD40 PF00400.27 ETO33542.1 - 1.3e-52 173.9 17.9 2e-09 36.9 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO33542.1 - 2.8e-12 46.7 0.8 0.003 17.3 0.0 3.3 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO33542.1 - 3.9e-06 25.4 0.1 0.018 13.3 0.0 2.4 2 1 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.3 ETO33542.1 - 2.1e-05 22.8 12.5 0.014 13.5 0.1 4.6 2 2 0 3 3 3 2 Nucleoporin Nup120/160 Me-amine-dh_H PF06433.6 ETO33542.1 - 0.0011 17.6 0.0 0.22 10.1 0.0 2.5 2 1 0 2 2 2 2 Methylamine dehydrogenase heavy chain (MADH) VEFS-Box PF09733.4 ETO33542.1 - 0.0038 16.8 0.0 0.25 11.0 0.0 2.6 2 0 0 2 2 2 1 VEFS-Box of polycomb protein Nbas_N PF15492.1 ETO33542.1 - 0.0043 16.1 0.5 4.8 6.2 0.0 3.8 2 2 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 ETO33542.1 - 0.0092 15.2 1.7 5.9 6.3 0.0 4.3 4 0 0 4 4 4 1 Proteasome subunit A N-terminal signature BBS2_Mid PF14783.1 ETO33542.1 - 0.011 15.5 0.7 4.6 7.0 0.0 4.1 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region PD40 PF07676.7 ETO33542.1 - 0.014 15.0 5.5 4.9 6.9 0.1 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO33542.1 - 0.02 14.3 0.2 0.23 10.8 0.1 2.2 2 0 0 2 2 2 0 PQQ-like domain DUF3601 PF12208.3 ETO33542.1 - 0.027 14.3 0.0 0.91 9.5 0.0 3.4 3 2 2 5 5 5 0 Domain of unknown function (DUF3601) DUF1652 PF07865.6 ETO33542.1 - 0.04 13.5 0.0 0.21 11.1 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1652) WD40 PF00400.27 ETO33545.1 - 1.1e-78 256.5 17.7 4.3e-14 51.7 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO33545.1 - 2.8e-08 32.3 4.5 0.09 10.8 0.0 5.4 1 1 5 6 6 6 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO33545.1 - 3.9e-07 28.7 3.3 0.011 14.0 0.0 3.2 1 1 1 3 3 3 3 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO33545.1 - 4.7e-05 22.9 0.1 0.0073 15.7 0.0 2.3 2 1 0 2 2 2 1 PQQ-like domain Nucleoporin_N PF08801.6 ETO33545.1 - 0.0001 21.2 11.9 0.45 9.2 0.2 5.1 1 1 2 4 4 4 3 Nup133 N terminal like Resistin PF06954.6 ETO33545.1 - 0.00018 21.6 0.0 53 4.1 0.0 5.1 2 1 2 5 5 5 0 Resistin SGL PF08450.7 ETO33545.1 - 0.00033 20.1 0.6 0.0095 15.3 0.0 2.9 1 1 1 3 3 3 1 SMP-30/Gluconolaconase/LRE-like region DUF4221 PF13970.1 ETO33545.1 - 0.0004 19.7 1.3 0.071 12.4 0.0 3.6 1 1 2 4 4 4 1 Domain of unknown function (DUF4221) Coatomer_WDAD PF04053.9 ETO33545.1 - 0.00045 19.1 8.1 0.0022 16.8 0.6 2.9 2 1 2 4 4 4 2 Coatomer WD associated region PD40 PF07676.7 ETO33545.1 - 0.00068 19.2 14.2 1.9 8.2 0.1 6.7 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 ETO33545.1 - 0.00085 18.4 1.5 0.85 8.6 0.0 3.8 2 2 2 4 4 4 1 Protein of unknown function (DUF1258) FmdE PF02663.9 ETO33545.1 - 0.0043 16.9 1.0 0.055 13.3 0.1 2.7 1 1 2 3 3 3 1 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Tox-PL PF15644.1 ETO33545.1 - 0.007 17.1 0.2 13 6.5 0.0 3.9 4 0 0 4 4 3 0 Papain fold toxin 1 IKI3 PF04762.7 ETO33545.1 - 0.021 12.6 0.3 0.79 7.4 0.1 2.2 1 1 1 2 2 2 0 IKI3 family SusE PF14292.1 ETO33545.1 - 0.021 14.6 0.1 56 3.5 0.0 4.1 4 0 0 4 4 4 0 SusE outer membrane protein Mid2 PF04478.7 ETO33545.1 - 0.29 10.5 5.0 5 6.5 0.1 3.8 3 1 1 4 4 4 0 Mid2 like cell wall stress sensor TraB PF01963.12 ETO33546.1 - 0.043 13.2 2.7 1.2 8.5 0.6 2.3 2 0 0 2 2 2 0 TraB family DUF2833 PF11090.3 ETO33547.1 - 0.028 14.5 0.2 0.063 13.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2833) Urocanase PF01175.13 ETO33548.1 - 0.067 11.2 0.1 0.073 11.1 0.0 1.0 1 0 0 1 1 1 0 Urocanase G-gamma PF00631.17 ETO33548.1 - 0.068 12.9 0.1 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 GGL domain Peptidase_M1 PF01433.15 ETO33549.1 - 5.8e-35 121.1 0.4 5.6e-17 61.9 0.0 2.1 1 1 1 2 2 2 2 Peptidase family M1 ETRAMP PF09716.5 ETO33550.1 - 0.0058 16.5 1.4 0.094 12.6 1.0 2.8 1 1 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) MIP-T3 PF10243.4 ETO33550.1 - 0.089 11.2 20.3 0.1 11.0 0.1 2.0 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Zip PF02535.17 ETO33550.1 - 0.22 10.5 5.6 6 5.7 3.9 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter GEMIN8 PF15348.1 ETO33550.1 - 1.3 9.0 13.6 3.5 7.5 5.4 2.2 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 Vfa1 PF08432.5 ETO33550.1 - 4.3 7.3 21.9 2.4 8.1 7.3 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 CobT PF06213.7 ETO33550.1 - 7.5 5.5 15.3 0.064 12.3 4.9 1.7 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT PalH PF08733.5 ETO33551.1 - 0.016 14.0 0.4 0.023 13.5 0.3 1.2 1 0 0 1 1 1 0 PalH/RIM21 Ax_dynein_light PF10211.4 ETO33552.1 - 1.4e-07 31.4 10.7 2.1e-07 30.9 7.4 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain DUF416 PF04222.7 ETO33552.1 - 0.0021 17.2 0.1 0.0021 17.2 0.1 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF416) SusD-like_2 PF12771.2 ETO33552.1 - 0.0029 16.0 0.7 0.0031 15.9 0.5 1.1 1 0 0 1 1 1 1 Starch-binding associating with outer membrane AAA_11 PF13086.1 ETO33552.1 - 0.095 12.2 3.4 0.13 11.8 2.4 1.2 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.4 ETO33552.1 - 0.36 9.7 9.1 0.44 9.4 6.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Syntaxin_2 PF14523.1 ETO33552.1 - 0.67 10.0 11.1 1.1 9.3 7.1 1.8 1 1 0 1 1 1 0 Syntaxin-like protein Mit_KHE1 PF10173.4 ETO33552.1 - 1.9 8.3 5.8 2 8.2 3.6 1.6 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF745 PF05335.8 ETO33552.1 - 2.6 7.5 6.7 2.7 7.4 1.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Med28 PF11594.3 ETO33552.1 - 3.2 8.0 11.1 2.1e+02 2.1 7.7 2.7 1 1 0 1 1 1 0 Mediator complex subunit 28 Peptidase_C97 PF05903.9 ETO33555.1 - 5.8e-15 55.3 0.6 9.6e-15 54.6 0.4 1.4 1 1 0 1 1 1 1 PPPDE putative peptidase domain DUF778 PF05608.7 ETO33555.1 - 0.081 12.8 0.1 0.16 11.8 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF778) TPR_12 PF13424.1 ETO33557.1 - 6.2e-34 115.7 0.9 1.6e-16 60.0 0.1 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO33557.1 - 2e-26 90.4 16.6 7.9e-08 31.5 1.0 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO33557.1 - 2.5e-24 84.7 10.2 1.1e-11 44.1 0.3 2.8 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 ETO33557.1 - 1.2e-20 71.6 9.5 1.8e-06 27.4 0.5 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO33557.1 - 2.9e-19 67.2 1.0 0.00034 20.2 0.0 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO33557.1 - 5e-18 63.4 18.2 8.9e-06 25.1 1.0 4.9 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO33557.1 - 1e-16 60.2 0.0 0.0026 17.6 0.0 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_6 PF13174.1 ETO33557.1 - 2.7e-08 33.7 5.5 0.008 16.5 0.2 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO33557.1 - 1.4e-07 31.6 0.2 0.0032 17.7 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO33557.1 - 1.7e-07 31.7 0.0 0.0019 18.8 0.0 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO33557.1 - 4.5e-07 29.5 4.2 2.3 8.6 0.0 4.9 4 1 0 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 ETO33557.1 - 1.4e-06 28.3 4.0 0.0085 16.2 0.4 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 ETO33557.1 - 4.1e-06 26.9 0.0 2.4 9.0 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO33557.1 - 0.0075 16.1 10.1 0.34 10.8 0.0 3.4 4 0 0 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat Pollen_allerg_1 PF01357.16 ETO33557.1 - 0.026 14.3 0.3 0.082 12.7 0.2 1.9 1 0 0 1 1 1 0 Pollen allergen PPR PF01535.15 ETO33557.1 - 0.046 13.7 1.1 3 8.0 0.1 3.3 3 0 0 3 3 3 0 PPR repeat Sel1 PF08238.7 ETO33557.1 - 0.15 12.7 2.6 0.77 10.4 0.2 2.9 2 0 0 2 2 2 0 Sel1 repeat DUF3753 PF12575.3 ETO33558.1 - 0.012 15.3 1.2 0.23 11.2 0.8 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3753) DUF3440 PF11922.3 ETO33558.1 - 0.026 14.0 0.2 1.3 8.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3440) Spuma_A9PTase PF03539.9 ETO33559.1 - 0.0068 16.3 0.9 0.013 15.4 0.6 1.5 1 0 0 1 1 1 1 Spumavirus aspartic protease (A9) Kelch_4 PF13418.1 ETO33560.1 - 7.1e-06 25.7 0.9 0.0034 17.1 0.0 3.3 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO33560.1 - 1.1e-05 24.9 1.7 0.0002 20.8 0.2 2.8 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.10 ETO33560.1 - 0.00013 21.5 1.9 0.059 13.1 0.2 3.9 4 1 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 ETO33560.1 - 0.00053 19.8 1.4 0.044 13.7 0.2 3.9 5 0 0 5 5 5 1 Kelch motif Kelch_6 PF13964.1 ETO33560.1 - 0.0077 16.3 4.1 0.18 12.0 0.2 3.7 3 1 1 4 4 4 1 Kelch motif Rtt102p PF09510.5 ETO33560.1 - 0.056 13.4 1.8 0.12 12.3 1.3 1.7 1 0 0 1 1 1 0 Rtt102p-like transcription regulator protein Kelch_3 PF13415.1 ETO33560.1 - 0.094 12.9 0.0 0.62 10.2 0.0 2.5 2 0 0 2 2 2 0 Galactose oxidase, central domain PUB PF09409.5 ETO33561.1 - 0.004 16.8 1.1 0.017 14.9 0.1 2.4 2 1 1 3 3 3 1 PUB domain PCEMA1 PF07418.6 ETO33561.1 - 0.098 12.0 8.8 0.17 11.2 6.1 1.3 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 Tetraspannin PF00335.15 ETO33561.1 - 2.5 7.3 7.9 0.71 9.1 2.6 2.2 2 1 0 2 2 2 0 Tetraspanin family PH PF00169.24 ETO33562.1 - 0.012 15.7 0.2 0.11 12.6 0.2 2.3 1 1 0 1 1 1 0 PH domain Rabaptin PF03528.10 ETO33563.1 - 0.011 15.6 2.8 0.011 15.6 1.9 2.4 2 1 0 2 2 2 0 Rabaptin DUF572 PF04502.8 ETO33563.1 - 0.1 11.7 7.9 0.19 10.8 5.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) CLASP_N PF12348.3 ETO33565.1 - 7.1e-05 22.2 0.2 0.0001 21.7 0.1 1.2 1 0 0 1 1 1 1 CLASP N terminal Adaptin_N PF01602.15 ETO33565.1 - 0.01 14.2 0.2 0.018 13.4 0.1 1.4 1 1 0 1 1 1 0 Adaptin N terminal region DUF155 PF02582.9 ETO33565.1 - 0.038 13.9 0.2 0.045 13.6 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 MutS_III PF05192.13 ETO33565.1 - 0.051 13.3 0.3 0.067 12.9 0.2 1.2 1 0 0 1 1 1 0 MutS domain III Katanin_con80 PF13925.1 ETO33565.1 - 0.081 12.6 1.1 0.22 11.2 0.3 1.8 2 0 0 2 2 2 0 con80 domain of Katanin COG5 PF10392.4 ETO33565.1 - 0.12 12.2 0.8 0.29 11.1 0.4 1.6 1 1 0 1 1 1 0 Golgi transport complex subunit 5 TPR_12 PF13424.1 ETO33566.1 - 2.1e-33 114.0 6.4 4.4e-12 45.7 0.0 4.3 3 1 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO33566.1 - 2.2e-22 78.4 9.6 1.6e-07 30.8 0.1 4.3 3 1 0 4 4 4 4 TPR repeat TPR_1 PF00515.23 ETO33566.1 - 4.8e-22 76.5 25.1 5e-06 25.8 0.7 6.2 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.1 ETO33566.1 - 2.1e-21 73.9 7.5 0.00061 19.4 0.0 5.8 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETO33566.1 - 5.8e-21 72.6 21.8 0.00028 20.5 0.5 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETO33566.1 - 3.6e-19 67.0 30.6 0.00028 20.4 0.1 6.7 6 1 0 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.1 ETO33566.1 - 7.3e-17 60.6 0.0 0.0047 16.8 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO33566.1 - 5e-09 36.0 9.1 0.37 11.3 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO33566.1 - 1.2e-05 25.8 0.1 2.9 8.6 0.1 4.5 3 2 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO33566.1 - 2.9e-05 24.1 1.1 2.9e-05 24.1 0.7 3.5 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 ETO33566.1 - 7.1e-05 22.6 6.1 0.34 10.8 0.2 4.7 3 2 1 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_14 PF13428.1 ETO33566.1 - 0.00014 22.2 0.0 10 7.0 0.0 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 ETO33566.1 - 0.00037 20.4 4.0 6.5 7.2 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO33566.1 - 0.011 16.0 2.0 2 8.8 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO33566.1 - 0.19 11.6 0.2 0.19 11.6 0.1 3.8 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat WD40 PF00400.27 ETO33568.1 - 2.5e-13 49.3 5.4 6.3e-12 44.9 0.1 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat 2OG-FeII_Oxy_2 PF13532.1 ETO33570.1 - 5e-28 98.2 0.0 2.6e-26 92.6 0.0 2.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3522 PF12036.3 ETO33571.1 - 2.8e-37 128.3 5.8 3.5e-37 127.9 4.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) Ceramidase PF05875.7 ETO33571.1 - 0.18 10.9 11.1 0.26 10.3 2.8 2.2 1 1 1 2 2 2 0 Ceramidase PEARLI-4 PF05278.7 ETO33572.1 - 0.0017 17.7 0.1 0.0017 17.7 0.1 2.7 1 1 2 3 3 3 1 Arabidopsis phospholipase-like protein (PEARLI 4) DUF725 PF05267.7 ETO33572.1 - 0.049 13.5 4.9 0.66 9.9 0.6 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF725) Radical_SAM_N PF08497.5 ETO33572.1 - 1.1 8.0 5.3 1.5 7.7 3.7 1.3 1 0 0 1 1 1 0 Radical SAM N-terminal DUF3523 PF12037.3 ETO33572.1 - 6.8 5.5 24.2 0.16 10.8 9.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3523) GvpK PF05121.7 ETO33576.1 - 0.0035 17.1 0.5 0.0035 17.1 0.4 1.8 2 1 0 2 2 2 1 Gas vesicle protein K Cob_adeno_trans PF01923.13 ETO33576.1 - 0.0053 16.5 1.6 0.0062 16.3 1.1 1.1 1 0 0 1 1 1 1 Cobalamin adenosyltransferase OmpH PF03938.9 ETO33576.1 - 0.0066 16.4 9.8 0.0083 16.0 6.8 1.1 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) DUF3887 PF13026.1 ETO33576.1 - 0.0081 16.4 7.8 0.0081 16.4 5.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3887) Clathrin_lg_ch PF01086.12 ETO33576.1 - 0.091 12.6 12.1 0.11 12.3 8.4 1.1 1 0 0 1 1 1 0 Clathrin light chain TSC22 PF01166.13 ETO33576.1 - 0.15 12.0 0.2 0.15 12.0 0.1 2.6 2 1 0 2 2 2 0 TSC-22/dip/bun family DUF3573 PF12097.3 ETO33576.1 - 0.41 9.1 6.0 0.47 9.0 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) FlgN PF05130.7 ETO33576.1 - 0.51 10.5 9.2 1.1 9.5 0.2 2.1 2 0 0 2 2 2 0 FlgN protein DIT1_PvcA PF05141.7 ETO33576.1 - 0.71 9.1 7.9 1.7 7.8 5.5 1.6 1 1 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein DUF4140 PF13600.1 ETO33576.1 - 1.5 9.3 4.9 0.69 10.3 0.3 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF342 PF03961.8 ETO33576.1 - 1.6 7.0 12.1 1.8 6.8 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) COQ7 PF03232.8 ETO33576.1 - 1.9 7.8 6.8 0.31 10.5 1.2 1.9 2 0 0 2 2 2 0 Ubiquinone biosynthesis protein COQ7 Viral_P18 PF04521.8 ETO33576.1 - 3 7.3 8.1 0.19 11.1 0.4 2.1 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein MitMem_reg PF13012.1 ETO33576.1 - 3.5 7.7 9.2 60 3.7 6.1 2.4 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Patched PF02460.13 ETO33576.1 - 4.5 5.0 5.5 5.2 4.8 3.8 1.1 1 0 0 1 1 1 0 Patched family Exonuc_VII_L PF02601.10 ETO33576.1 - 4.6 6.3 12.4 4.9 6.2 8.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Bestrophin PF01062.16 ETO33576.1 - 5.1 5.9 5.6 0.77 8.6 0.2 1.8 1 1 1 2 2 2 0 Bestrophin, RFP-TM, chloride channel GrpE PF01025.14 ETO33576.1 - 6.7 6.2 13.3 20 4.6 9.3 1.6 1 1 0 1 1 1 0 GrpE BMFP PF04380.8 ETO33576.1 - 7.2 6.8 8.5 19 5.4 0.5 2.3 2 1 0 2 2 2 0 Membrane fusogenic activity C6 PF01681.12 ETO33577.1 - 0.024 14.6 0.2 0.034 14.2 0.1 1.2 1 0 0 1 1 1 0 C6 domain PGP_phosphatase PF09419.5 ETO33577.1 - 0.081 12.2 1.6 0.1 11.9 0.5 1.6 1 1 1 2 2 2 0 Mitochondrial PGP phosphatase PT PF04886.7 ETO33578.1 - 2.1e-20 71.7 149.4 1.1e+03 -1.0 26.9 8.3 1 1 2 3 3 3 0 PT repeat TSP_1 PF00090.14 ETO33578.1 - 2.3e-05 24.3 10.4 6.6e-05 22.9 7.2 1.9 1 0 0 1 1 1 1 Thrombospondin type 1 domain CDC45 PF02724.9 ETO33578.1 - 0.59 8.1 6.9 0.93 7.4 4.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Hex_IIIa PF02455.11 ETO33579.1 - 1 7.9 9.7 1.2 7.7 6.7 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) PIG-S PF10510.4 ETO33579.1 - 2.6 6.5 9.4 2.8 6.5 6.5 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein FPN1 PF06963.7 ETO33579.1 - 8.2 4.6 9.2 15 3.8 6.4 1.3 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF3347 PF11827.3 ETO33579.1 - 8.3 6.3 17.3 11 5.9 12.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) WD40 PF00400.27 ETO33580.1 - 1.9e-51 170.1 18.0 1.7e-09 37.1 0.2 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat SART-1 PF03343.8 ETO33580.1 - 0.011 14.1 4.4 0.014 13.7 3.1 1.1 1 0 0 1 1 1 0 SART-1 family Myotub-related PF06602.9 ETO33581.1 - 8.2e-58 195.8 1.7 8.2e-58 195.8 1.2 1.5 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain PCIF1_WW PF12237.3 ETO33581.1 - 0.054 12.7 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Phosphorylated CTD interacting factor 1 WW domain Myotub-related PF06602.9 ETO33582.1 - 2.6e-43 148.1 1.0 4.1e-43 147.5 0.7 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain 3-PAP PF12578.3 ETO33582.1 - 6.5e-05 22.8 0.9 0.0001 22.2 0.2 1.8 2 1 0 2 2 2 1 Myotubularin-associated protein LRR_4 PF12799.2 ETO33583.1 - 3e-09 36.3 21.1 0.00023 20.7 0.6 5.1 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETO33583.1 - 1.4e-05 24.4 25.2 0.38 10.9 0.1 9.2 10 0 0 10 10 10 3 Leucine Rich Repeat LRR_8 PF13855.1 ETO33583.1 - 0.00012 21.7 1.0 0.00012 21.7 0.7 4.6 2 1 2 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 ETO33583.1 - 0.12 12.4 9.5 10 6.5 0.0 5.5 5 1 1 6 6 6 0 Leucine Rich repeat LRR_7 PF13504.1 ETO33583.1 - 0.63 10.4 12.0 66 4.3 0.0 6.7 6 0 0 6 6 6 0 Leucine rich repeat ABC_ATPase PF09818.4 ETO33584.1 - 3.7e-117 391.6 2.1 1.6e-115 386.2 1.5 2.8 1 1 0 1 1 1 1 Predicted ATPase of the ABC class AAA_25 PF13481.1 ETO33584.1 - 0.14 11.5 0.0 0.48 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Asp_protease_2 PF13650.1 ETO33587.1 - 0.12 12.8 0.1 0.59 10.6 0.0 2.1 2 0 0 2 2 2 0 Aspartyl protease DUF4296 PF14129.1 ETO33588.1 - 0.00058 19.9 6.4 0.002 18.2 2.7 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4296) DUF3166 PF11365.3 ETO33588.1 - 0.081 13.3 2.9 0.26 11.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) DUF342 PF03961.8 ETO33588.1 - 2.9 6.2 10.9 3.5 5.9 7.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Bud13 PF09736.4 ETO33589.1 - 0.061 13.5 5.8 0.082 13.1 4.0 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex AAA_23 PF13476.1 ETO33589.1 - 0.97 9.7 7.8 1.4 9.1 5.3 1.3 1 1 0 1 1 1 0 AAA domain zf-CCCH PF00642.19 ETO33591.1 - 4e-09 35.9 5.5 8.1e-09 34.9 3.8 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 ETO33591.1 - 0.097 12.7 1.1 0.21 11.6 0.7 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type PSCyt2 PF07583.6 ETO33592.1 - 0.012 15.1 1.1 0.014 14.8 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1549) Ceramidase PF05875.7 ETO33593.1 - 1.8e-28 99.4 23.1 2.7e-28 98.8 16.0 1.2 1 0 0 1 1 1 1 Ceramidase YrvL PF14184.1 ETO33593.1 - 0.14 11.9 10.2 1.7 8.4 0.2 2.3 1 1 1 2 2 2 0 Regulatory protein YrvL MerC PF03203.9 ETO33593.1 - 3.5 8.0 11.1 0.43 10.9 2.8 2.5 2 1 0 2 2 2 0 MerC mercury resistance protein CTP_transf_1 PF01148.15 ETO33593.1 - 6.4 6.3 15.0 1.9 8.0 8.2 1.6 1 1 1 2 2 2 0 Cytidylyltransferase family BLYB PF05289.6 ETO33594.1 - 0.013 15.3 1.2 0.041 13.6 0.3 2.2 1 1 1 2 2 2 0 Borrelia hemolysin accessory protein DUF2368 PF10166.4 ETO33594.1 - 0.25 10.9 0.0 0.25 10.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) Codanin-1_C PF15296.1 ETO33596.1 - 1.3 8.8 6.1 2.8 7.8 4.2 1.6 1 1 0 1 1 1 0 Codanin-1 C-terminus Na_trans_assoc PF06512.8 ETO33597.1 - 0.1 12.5 11.2 0.13 12.1 7.8 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated DUF4482 PF14818.1 ETO33597.1 - 1.1 9.9 8.9 0.058 14.0 1.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4482) Striatin PF08232.7 ETO33597.1 - 6.4 7.0 7.5 5.2 7.3 4.2 1.5 2 0 0 2 2 2 0 Striatin family Mpv17_PMP22 PF04117.7 ETO33598.1 - 2.3e-17 62.3 1.0 2.3e-17 62.3 0.7 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family DcpS_C PF11969.3 ETO33599.1 - 4.9e-16 59.0 1.3 1.2e-15 57.7 0.2 2.2 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 ETO33599.1 - 1.9e-08 34.7 0.0 4.7e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 HIT domain DUF3276 PF11680.3 ETO33599.1 - 0.0064 16.2 0.0 0.023 14.4 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3276) DUF726 PF05277.7 ETO33600.1 - 3.3e-83 279.4 8.5 3.5e-35 121.5 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF726) Lin-8 PF03353.10 ETO33600.1 - 7.3e-05 22.1 14.1 7.3e-05 22.1 9.8 3.2 3 0 0 3 3 3 1 Ras-mediated vulval-induction antagonist Nop14 PF04147.7 ETO33600.1 - 0.0023 15.9 27.9 0.0023 15.9 19.3 3.0 3 0 0 3 3 3 1 Nop14-like family Abhydrolase_5 PF12695.2 ETO33600.1 - 0.0026 17.5 0.2 0.0057 16.4 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family SPX PF03105.14 ETO33600.1 - 0.71 9.6 54.0 0.21 11.3 2.2 3.3 3 0 0 3 3 3 0 SPX domain Daxx PF03344.10 ETO33600.1 - 3.2 6.1 77.9 0.026 13.0 18.0 3.0 3 0 0 3 3 3 0 Daxx Family Zip PF02535.17 ETO33600.1 - 6 5.7 23.3 2.5 7.0 0.0 3.8 3 1 0 3 3 3 0 ZIP Zinc transporter Kelch_6 PF13964.1 ETO33601.1 - 5.5e-10 38.9 1.3 1.5e-05 24.9 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO33601.1 - 1.7e-06 27.4 4.1 3.1e-05 23.4 0.0 4.0 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.1 ETO33601.1 - 1.3e-05 24.8 0.3 0.0011 18.7 0.0 3.6 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO33601.1 - 3.3e-05 23.9 0.1 0.012 15.7 0.0 3.5 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO33601.1 - 0.0026 17.6 0.1 0.063 13.2 0.1 2.8 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.10 ETO33601.1 - 0.091 12.5 1.2 1.4 8.8 0.0 3.4 3 2 0 3 3 3 0 Kelch motif DNA_pol_E_B PF04042.11 ETO33602.1 - 1.9e-20 73.0 1.8 3.7e-20 72.0 1.2 1.5 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Calpain_III PF01067.17 ETO33603.1 - 0.00016 21.3 0.0 0.0002 21.0 0.0 1.2 1 0 0 1 1 1 1 Calpain large subunit, domain III Tim54 PF11711.3 ETO33603.1 - 0.01 14.4 0.3 0.011 14.4 0.2 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 WD40 PF00400.27 ETO33604.1 - 1.2e-19 69.3 0.5 3.9e-09 36.0 0.0 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO33604.1 - 0.00066 17.9 0.2 0.018 13.1 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Daxx PF03344.10 ETO33605.1 - 0.18 10.2 13.0 0.26 9.7 9.0 1.2 1 0 0 1 1 1 0 Daxx Family Secretin_N_2 PF07655.8 ETO33605.1 - 0.47 10.8 9.4 0.98 9.8 6.5 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain DUF2076 PF09849.4 ETO33605.1 - 1.7 8.6 9.2 2.4 8.1 6.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) CobT PF06213.7 ETO33605.1 - 1.9 7.5 15.3 2.8 7.0 10.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Copper-bind PF00127.15 ETO33606.1 - 0.03 14.5 0.3 0.096 12.9 0.0 2.0 2 0 0 2 2 2 0 Copper binding proteins, plastocyanin/azurin family Kelch_5 PF13854.1 ETO33606.1 - 0.042 13.8 0.1 5.8 6.9 0.0 3.0 3 0 0 3 3 3 0 Kelch motif Colicin_V PF02674.11 ETO33607.1 - 0.055 13.3 4.8 0.087 12.6 3.3 1.3 1 0 0 1 1 1 0 Colicin V production protein SPRY PF00622.23 ETO33608.1 - 6e-05 23.1 0.0 8.1e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 SPRY domain DUF4511 PF14974.1 ETO33608.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4511) AMP-binding PF00501.23 ETO33609.1 - 3.8e-13 48.6 0.3 2.8e-09 35.8 0.0 2.6 3 0 0 3 3 3 2 AMP-binding enzyme AMP-binding PF00501.23 ETO33610.1 - 2.5e-10 39.3 0.1 3.7e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme WD40 PF00400.27 ETO33611.1 - 6.3e-104 336.5 41.5 7e-14 51.0 0.1 10.8 11 0 0 11 11 11 10 WD domain, G-beta repeat eIF2A PF08662.6 ETO33611.1 - 4.3e-19 68.9 0.4 0.00016 21.4 0.0 5.4 1 1 4 5 5 5 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO33611.1 - 7.8e-14 50.7 12.0 0.02 13.0 0.0 6.7 1 1 5 7 7 7 5 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO33611.1 - 1.3e-12 46.6 1.6 0.0015 16.9 0.0 5.2 1 1 6 7 7 7 5 Cytochrome D1 heme domain PD40 PF07676.7 ETO33611.1 - 6e-12 44.9 14.6 0.0099 15.5 0.0 8.4 9 0 0 9 9 9 4 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO33611.1 - 9.9e-11 41.0 18.2 0.00071 18.4 0.1 6.0 2 2 3 5 5 5 4 Nup133 N terminal like Coatomer_WDAD PF04053.9 ETO33611.1 - 2.8e-08 33.0 1.2 0.00019 20.3 0.5 3.2 1 1 1 3 3 3 2 Coatomer WD associated region PQQ_2 PF13360.1 ETO33611.1 - 1.5e-07 31.1 2.2 0.0012 18.3 0.0 3.4 1 1 1 2 2 2 2 PQQ-like domain DUF1258 PF06869.7 ETO33611.1 - 1.9e-07 30.4 5.4 0.74 8.8 0.0 5.5 3 1 3 6 6 6 3 Protein of unknown function (DUF1258) Me-amine-dh_H PF06433.6 ETO33611.1 - 6.6e-06 24.9 0.0 0.047 12.3 0.0 3.6 2 1 2 5 5 5 2 Methylamine dehydrogenase heavy chain (MADH) Mid2 PF04478.7 ETO33611.1 - 0.0013 18.2 4.3 1.5 8.1 0.0 4.8 2 1 2 5 5 5 1 Mid2 like cell wall stress sensor DUF3732 PF12532.3 ETO33611.1 - 0.011 15.2 0.5 11 5.4 0.0 4.1 4 2 2 6 6 6 0 Protein of unknown function (DUF3732) Resistin PF06954.6 ETO33611.1 - 0.02 15.1 8.5 8.8 6.6 0.0 6.2 4 2 5 9 9 8 0 Resistin Methyltransf_3 PF01596.12 ETO33611.1 - 0.049 12.6 0.0 5.9 5.8 0.0 3.6 2 2 1 3 3 3 0 O-methyltransferase PLD_C PF12357.3 ETO33611.1 - 0.15 11.5 1.5 74 2.9 0.0 5.5 8 1 1 9 9 9 0 Phospholipase D C terminal Proteasome_A_N PF10584.4 ETO33611.1 - 0.34 10.2 24.8 6.8 6.1 0.0 8.2 9 0 0 9 9 9 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 ETO33612.1 - 6.1e-10 38.5 2.2 1.3e-09 37.5 0.4 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat NACHT PF05729.7 ETO33612.1 - 3e-06 27.0 0.0 8.2e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Pentapeptide PF00805.17 ETO33612.1 - 2e-05 23.7 0.7 6.9e-05 21.9 0.5 2.0 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) AAA_18 PF13238.1 ETO33612.1 - 0.00013 22.2 3.6 0.00085 19.6 0.0 3.8 3 1 1 4 4 4 1 AAA domain Pentapeptide_4 PF13599.1 ETO33612.1 - 0.0027 17.4 0.0 0.0072 16.1 0.0 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 ETO33612.1 - 0.0068 16.2 0.4 0.029 14.2 0.2 2.0 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) ABC_tran PF00005.22 ETO33612.1 - 0.015 15.6 0.1 0.83 9.9 0.0 3.3 2 1 0 2 2 2 0 ABC transporter AAA_22 PF13401.1 ETO33612.1 - 0.016 15.3 0.0 0.083 13.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 ETO33612.1 - 0.025 15.3 0.0 0.15 12.9 0.0 2.4 1 0 0 1 1 1 0 AAA domain SAM_1 PF00536.25 ETO33613.1 - 0.032 14.4 0.0 0.065 13.4 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO33613.1 - 0.064 13.1 0.2 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Cut8_C PF08559.5 ETO33614.1 - 0.11 12.3 0.8 0.27 11.0 0.1 1.8 2 0 0 2 2 2 0 Cut8 six-helix bundle SPRY PF00622.23 ETO33615.1 - 1.7e-28 99.1 0.5 3.5e-28 98.1 0.3 1.6 1 0 0 1 1 1 1 SPRY domain WD40 PF00400.27 ETO33616.1 - 3.4e-06 26.7 2.1 9.3e-05 22.1 0.3 2.6 2 1 0 2 2 2 2 WD domain, G-beta repeat WD40 PF00400.27 ETO33617.1 - 6.3e-17 60.7 3.4 5.2e-11 41.9 0.2 3.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO33617.1 - 0.024 12.8 0.5 2.9 5.9 0.0 1.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO33617.1 - 0.13 11.0 0.6 0.66 8.6 0.4 1.9 1 1 0 1 1 1 0 Nup133 N terminal like zf-RING_2 PF13639.1 ETO33618.1 - 0.0014 18.3 1.1 0.0045 16.7 0.8 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO33618.1 - 0.0027 17.6 0.9 0.019 14.9 0.6 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-BED PF02892.10 ETO33618.1 - 0.58 9.9 4.1 0.55 10.0 0.1 2.7 3 0 0 3 3 3 0 BED zinc finger zf-rbx1 PF12678.2 ETO33618.1 - 1 9.5 6.4 1 9.4 3.2 2.0 1 1 1 2 2 2 0 RING-H2 zinc finger zf-RING-like PF08746.6 ETO33618.1 - 2.4 8.2 6.1 16 5.5 4.3 2.4 1 1 1 2 2 2 0 RING-like domain WD40 PF00400.27 ETO33619.1 - 9.3e-33 110.9 13.1 5.9e-12 44.9 0.0 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO33619.1 - 4.8e-08 31.6 5.2 0.00056 18.1 0.7 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 DUF4164 PF13747.1 ETO33619.1 - 0.0021 18.1 12.4 0.0026 17.8 2.5 2.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4164) RapA_C PF12137.3 ETO33619.1 - 0.24 10.2 15.8 0.4 9.4 10.9 1.4 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal CtIP_N PF10482.4 ETO33619.1 - 0.25 11.1 21.0 0.11 12.3 12.6 1.7 1 1 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain Lebercilin PF15619.1 ETO33619.1 - 0.36 10.2 27.6 0.25 10.7 14.6 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease PilJ PF13675.1 ETO33619.1 - 0.47 10.7 3.4 6.1 7.1 0.1 2.3 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term RVT_3 PF13456.1 ETO33619.1 - 0.54 10.0 3.8 1.1 9.0 0.2 2.5 1 1 1 2 2 2 0 Reverse transcriptase-like DUF3584 PF12128.3 ETO33619.1 - 0.62 7.3 22.2 0.82 6.9 15.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MAD PF05557.8 ETO33619.1 - 0.72 7.8 29.7 1 7.3 20.6 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein V_ATPase_I PF01496.14 ETO33619.1 - 0.73 7.6 16.0 0.89 7.3 11.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATG16 PF08614.6 ETO33619.1 - 0.94 9.2 27.5 0.043 13.6 11.8 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Cob_adeno_trans PF01923.13 ETO33619.1 - 1.1 9.0 6.2 2.1 8.1 4.3 1.5 1 0 0 1 1 1 0 Cobalamin adenosyltransferase TBPIP PF07106.8 ETO33619.1 - 1.2 8.6 31.2 2.7 7.4 7.5 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CENP-Q PF13094.1 ETO33619.1 - 1.7 8.6 18.6 1.4 8.8 3.0 2.7 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Cytochrom_B562 PF07361.6 ETO33619.1 - 2.1 8.7 13.0 1.2 9.5 6.7 2.1 1 1 1 2 2 2 0 Cytochrome b562 APG6 PF04111.7 ETO33619.1 - 2.1 7.2 28.1 0.27 10.2 13.3 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 IpaC_SipC PF09599.5 ETO33619.1 - 2.3 7.1 15.3 3.7 6.4 10.3 1.6 1 1 0 1 1 1 0 Salmonella-Shigella invasin protein C (IpaC_SipC) FliT PF05400.8 ETO33619.1 - 2.5 8.5 10.7 10 6.6 0.9 2.4 2 0 0 2 2 2 0 Flagellar protein FliT IncA PF04156.9 ETO33619.1 - 3.5 7.1 25.7 48 3.4 17.9 2.1 1 1 0 1 1 1 0 IncA protein Mnd1 PF03962.10 ETO33619.1 - 3.6 7.2 27.2 0.22 11.1 14.1 2.2 2 1 1 3 3 3 0 Mnd1 family Baculo_PEP_C PF04513.7 ETO33619.1 - 4.5 7.0 19.2 3.2 7.5 10.5 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1515 PF07439.6 ETO33619.1 - 6.6 6.5 7.1 5.4 6.8 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Vfa1 PF08432.5 ETO33619.1 - 7.7 6.4 20.8 12 5.8 14.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF972 PF06156.8 ETO33619.1 - 8.1 6.8 23.0 14 6.0 7.5 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Fib_alpha PF08702.5 ETO33619.1 - 8.5 6.4 28.5 0.16 12.1 7.7 2.4 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Cation_efflux PF01545.16 ETO33620.1 - 5.6e-05 22.3 4.2 8.8e-05 21.7 2.9 1.2 1 0 0 1 1 1 1 Cation efflux family DUF2562 PF10814.3 ETO33620.1 - 0.05 13.5 0.1 0.09 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2562) UPF0016 PF01169.14 ETO33620.1 - 0.055 13.6 0.7 0.14 12.3 0.4 1.8 1 1 0 1 1 1 0 Uncharacterized protein family UPF0016 DUF3995 PF13160.1 ETO33620.1 - 0.11 12.6 1.2 0.48 10.4 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3995) DUF202 PF02656.10 ETO33620.1 - 5.3 7.3 6.5 0.5 10.6 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF202) RRM_1 PF00076.17 ETO33621.1 - 4.8e-20 70.9 0.0 1.1e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO33621.1 - 2.7e-14 52.9 0.1 5.1e-14 51.9 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO33621.1 - 3.1e-11 42.9 0.0 6.1e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETO33621.1 - 0.00013 21.6 0.0 0.00037 20.2 0.0 1.7 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 ETO33621.1 - 0.018 14.8 0.2 0.22 11.3 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif MFS_1 PF07690.11 ETO33622.1 - 9.6e-13 47.5 14.2 1.3e-12 47.0 9.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Ninjurin PF04923.7 ETO33622.1 - 0.11 12.1 5.1 1.4 8.6 0.3 2.5 2 0 0 2 2 2 0 Ninjurin Spore_YabQ PF09578.5 ETO33622.1 - 0.79 9.7 8.8 0.46 10.4 1.4 2.4 1 1 1 2 2 2 0 Spore cortex protein YabQ (Spore_YabQ) DUF1440 PF07274.7 ETO33622.1 - 1.9 8.4 6.9 0.38 10.7 0.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1440) Peptidase_C14 PF00656.17 ETO33624.1 - 0.013 15.1 0.1 0.024 14.3 0.1 1.4 1 0 0 1 1 1 0 Caspase domain PRCC PF10253.4 ETO33625.1 - 0.27 11.9 5.6 0.15 12.7 2.4 1.6 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting CDC45 PF02724.9 ETO33625.1 - 0.68 7.9 5.9 0.97 7.3 4.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DENN PF02141.16 ETO33627.1 - 1.6e-22 80.1 3.0 2e-22 79.8 2.1 1.1 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 ETO33627.1 - 0.014 15.3 0.0 0.035 14.0 0.0 1.7 1 0 0 1 1 1 0 uDENN domain DUF3397 PF11877.3 ETO33627.1 - 0.64 10.0 8.4 1.6 8.7 5.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3397) PDZ PF00595.19 ETO33628.1 - 1.7e-05 24.9 0.0 2.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 ETO33628.1 - 0.00028 20.7 0.0 0.00042 20.1 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Zip PF02535.17 ETO33628.1 - 0.00029 19.9 0.2 0.0003 19.8 0.1 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter DUF912 PF06024.7 ETO33628.1 - 0.051 13.6 0.0 0.085 12.9 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SelP_N PF04592.9 ETO33628.1 - 0.8 9.0 7.5 1.1 8.6 5.2 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region WD40 PF00400.27 ETO33629.1 - 2.2e-09 36.8 2.4 0.28 11.1 0.0 7.0 7 0 0 7 7 7 2 WD domain, G-beta repeat PQQ PF01011.16 ETO33629.1 - 0.018 14.5 0.1 0.069 12.7 0.0 2.2 2 0 0 2 2 2 0 PQQ enzyme repeat PQQ_2 PF13360.1 ETO33629.1 - 0.025 14.0 0.1 0.073 12.5 0.1 1.7 1 1 0 1 1 1 0 PQQ-like domain SGL PF08450.7 ETO33629.1 - 0.036 13.4 0.3 1.4 8.2 0.1 3.1 3 0 0 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region MAPEG PF01124.13 ETO33631.1 - 0.011 15.3 0.1 0.011 15.3 0.0 2.2 2 1 0 2 2 2 0 MAPEG family DUF3382 PF11862.3 ETO33631.1 - 0.64 9.9 4.6 3 7.8 2.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3382) Cation_ATPase_C PF00689.16 ETO33631.1 - 0.89 9.0 5.2 1.5 8.3 3.6 1.5 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus WD40 PF00400.27 ETO33632.1 - 5e-25 86.4 4.7 1.5e-08 34.2 0.1 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO33632.1 - 1.6e-10 39.7 0.6 5.1e-06 24.9 0.1 2.9 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO33632.1 - 0.0009 18.0 3.6 1.3 7.6 0.1 3.1 1 1 2 3 3 3 3 Nup133 N terminal like Cast PF10174.4 ETO33632.1 - 0.0085 14.1 0.2 0.0088 14.1 0.1 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Arena_nucleocap PF00843.12 ETO33632.1 - 0.034 12.0 0.2 1.9 6.2 0.0 2.9 2 1 1 3 3 3 0 Arenavirus nucleocapsid protein Peptidase_M64 PF09471.5 ETO33632.1 - 0.041 13.5 0.3 0.041 13.5 0.2 1.6 2 0 0 2 2 2 0 IgA Peptidase M64 WD40 PF00400.27 ETO33633.1 - 5e-148 476.3 35.6 6.1e-14 51.2 0.0 12.4 12 0 0 12 12 12 12 WD domain, G-beta repeat PQQ_2 PF13360.1 ETO33633.1 - 1.9e-14 53.6 1.6 0.0058 16.1 0.1 4.9 1 1 2 4 4 4 4 PQQ-like domain PD40 PF07676.7 ETO33633.1 - 3.3e-07 29.8 15.0 2.3 8.0 0.0 9.1 10 0 0 10 10 10 1 WD40-like Beta Propeller Repeat Gmad1 PF10647.4 ETO33633.1 - 1e-05 25.0 0.1 1.5 8.1 0.0 5.3 3 1 2 5 5 5 2 Lipoprotein LpqB beta-propeller domain Cytochrom_D1 PF02239.11 ETO33633.1 - 0.00023 19.5 5.1 3.5 5.8 0.1 4.9 3 2 3 6 6 6 4 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 ETO33633.1 - 0.0013 18.0 8.0 71 2.8 0.0 7.2 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature DUF1652 PF07865.6 ETO33633.1 - 0.0038 16.7 0.0 33 4.1 0.0 6.1 8 0 0 8 8 8 0 Protein of unknown function (DUF1652) Pentapeptide PF00805.17 ETO33633.1 - 0.0041 16.3 2.1 0.017 14.3 0.7 2.2 1 1 1 2 2 2 2 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 ETO33633.1 - 0.0047 16.7 1.1 0.016 15.0 0.8 2.0 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.1 ETO33633.1 - 0.005 16.6 1.7 0.013 15.2 1.2 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) DUF3379 PF11859.3 ETO33633.1 - 0.027 13.6 1.5 0.41 9.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3379) dsrm PF00035.20 ETO33633.1 - 0.028 15.0 0.4 70 4.1 0.0 5.0 7 0 0 7 7 5 0 Double-stranded RNA binding motif Mid2 PF04478.7 ETO33633.1 - 0.07 12.5 5.2 27 4.1 0.0 5.8 5 3 2 8 8 8 0 Mid2 like cell wall stress sensor RUN PF02759.14 ETO33634.1 - 6.2e-08 32.4 0.1 6.2e-08 32.4 0.1 2.0 2 0 0 2 2 2 1 RUN domain CDC45 PF02724.9 ETO33634.1 - 7.9 4.3 24.2 0.64 7.9 13.3 1.7 2 0 0 2 2 2 0 CDC45-like protein CENP-B_dimeris PF09026.5 ETO33635.1 - 0.12 12.5 0.3 0.12 12.5 0.2 2.3 1 1 1 2 2 2 0 Centromere protein B dimerisation domain WD40 PF00400.27 ETO33636.1 - 1.3e-61 202.3 20.4 1.8e-11 43.4 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO33636.1 - 1.2e-12 46.8 0.6 0.045 11.8 0.0 5.2 1 1 2 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO33636.1 - 0.0019 17.0 13.4 3.6 6.2 6.3 3.9 2 1 1 3 3 3 1 Nup133 N terminal like DUF4221 PF13970.1 ETO33636.1 - 0.052 12.8 3.4 0.23 10.7 0.5 2.8 1 1 1 3 3 3 0 Domain of unknown function (DUF4221) PQQ PF01011.16 ETO33636.1 - 0.086 12.4 0.0 0.33 10.5 0.0 2.0 1 0 0 1 1 1 0 PQQ enzyme repeat PQQ_3 PF13570.1 ETO33636.1 - 0.11 12.7 0.4 5.1 7.4 0.1 3.4 3 0 0 3 3 3 0 PQQ-like domain DUF851 PF05867.6 ETO33636.1 - 0.13 11.5 0.0 15 4.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF851) WD40 PF00400.27 ETO33637.1 - 1.4e-60 199.1 31.4 1.2e-11 43.9 0.2 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO33637.1 - 1.2e-13 50.0 10.7 0.0017 16.5 0.1 6.0 1 1 5 6 6 6 6 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO33637.1 - 0.0015 18.4 0.1 0.85 9.5 0.0 3.4 2 1 1 3 3 3 2 Domain of unknown function (DUF3601) WD40 PF00400.27 ETO33638.1 - 1.5e-59 195.8 25.9 1e-10 41.0 0.0 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO33638.1 - 6.2e-09 34.5 2.8 0.096 10.8 0.0 5.7 4 2 2 6 6 6 5 Nucleoporin Nup120/160 DUF851 PF05867.6 ETO33638.1 - 0.11 11.7 0.0 2.8 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF851) WD40 PF00400.27 ETO33639.1 - 2.2e-52 173.1 19.4 4.2e-11 42.2 2.0 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO33639.1 - 1.1e-08 33.7 5.4 0.041 12.0 0.1 5.0 1 1 4 5 5 5 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO33639.1 - 0.26 10.7 1.4 52 3.1 0.0 3.2 2 1 1 3 3 3 0 PQQ-like domain PQQ_3 PF13570.1 ETO33639.1 - 0.31 11.3 1.2 15 5.9 0.2 3.8 6 0 0 6 6 6 0 PQQ-like domain Acetyltransf_9 PF13527.1 ETO33640.1 - 0.0066 16.3 0.0 0.012 15.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETO33640.1 - 0.0072 16.3 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETO33640.1 - 0.0077 16.3 0.0 0.026 14.6 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETO33640.1 - 0.11 12.6 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3301 PF11743.3 ETO33640.1 - 0.12 11.8 0.2 0.22 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) Acetyltransf_8 PF13523.1 ETO33640.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain WD40 PF00400.27 ETO33641.1 - 3e-35 118.8 15.8 5.4e-11 41.9 0.3 5.7 5 2 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO33641.1 - 1.4e-05 23.4 0.5 0.39 8.7 0.1 3.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO33641.1 - 0.17 10.6 9.9 1.5 7.5 6.1 2.4 1 1 1 2 2 2 0 Nup133 N terminal like DUF1422 PF07226.6 ETO33642.1 - 0.067 12.9 0.2 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) Arm PF00514.18 ETO33643.1 - 0.053 13.3 0.6 9.8 6.1 0.0 3.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Ctr PF04145.10 ETO33643.1 - 0.98 9.4 13.5 3.6 7.6 0.2 4.5 3 2 0 4 4 4 0 Ctr copper transporter family WD40 PF00400.27 ETO33644.1 - 1.7e-63 208.3 27.7 6.3e-11 41.7 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO33644.1 - 1.5e-10 39.9 2.8 0.0012 17.1 0.1 4.5 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Arch_flagellin PF01917.11 ETO33645.1 - 0.015 14.8 0.1 0.026 14.1 0.0 1.5 1 1 0 1 1 1 0 Archaebacterial flagellin SAM_1 PF00536.25 ETO33645.1 - 0.022 14.9 0.0 0.042 14.0 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO33645.1 - 0.038 13.8 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF4613 PF15390.1 ETO33646.1 - 0.72 7.9 7.2 0.86 7.6 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF2968 PF11180.3 ETO33646.1 - 1.3 8.3 8.7 2.1 7.7 5.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) BSP_II PF05432.6 ETO33647.1 - 0.00036 19.9 10.1 0.00036 19.9 7.0 1.8 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) Myc_N PF01056.13 ETO33647.1 - 0.0017 17.5 3.0 0.0017 17.5 2.1 2.1 2 1 0 2 2 2 1 Myc amino-terminal region Nucleoplasmin PF03066.10 ETO33647.1 - 0.0096 15.4 10.6 0.0096 15.4 7.4 2.0 2 0 0 2 2 2 1 Nucleoplasmin RNA_pol_Rpc4 PF05132.9 ETO33647.1 - 0.0099 15.8 3.2 0.0099 15.8 2.2 2.7 3 0 0 3 3 3 1 RNA polymerase III RPC4 CDC27 PF09507.5 ETO33647.1 - 1.4 8.0 25.6 0.14 11.3 3.4 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 DUF1510 PF07423.6 ETO33647.1 - 2 7.7 23.8 0.92 8.8 7.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Spore_coat_CotO PF14153.1 ETO33647.1 - 3.7 6.9 21.2 1.6 8.1 4.3 2.2 2 0 0 2 2 2 0 Spore coat protein CotO Prothymosin PF03247.9 ETO33647.1 - 4.2 7.5 37.0 0.048 13.8 13.6 2.3 2 0 0 2 2 2 0 Prothymosin/parathymosin family Ribonuc_2-5A PF06479.7 ETO33648.1 - 0.0062 16.3 2.5 0.78 9.5 0.4 2.5 2 0 0 2 2 2 2 Ribonuclease 2-5A DUF4485 PF14846.1 ETO33648.1 - 0.016 14.9 5.0 0.69 9.6 0.1 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4485) HEAT PF02985.17 ETO33648.1 - 0.034 14.2 0.5 0.3 11.2 0.0 2.8 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.1 ETO33648.1 - 0.082 13.2 0.0 0.51 10.6 0.0 2.1 2 0 0 2 2 2 0 HEAT repeats dNK PF01712.14 ETO33648.1 - 0.11 12.4 3.3 0.11 12.4 0.5 2.2 1 1 1 2 2 2 0 Deoxynucleoside kinase HMG-CoA_red PF00368.13 ETO33648.1 - 0.16 10.6 0.1 0.21 10.2 0.1 1.3 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A reductase Anticodon_1 PF08264.8 ETO33648.1 - 0.69 9.6 3.9 5 6.8 0.3 2.7 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA HEAT_2 PF13646.1 ETO33649.1 - 7.5e-06 26.1 0.1 1 9.7 0.0 3.1 2 1 1 3 3 3 2 HEAT repeats FPL PF09758.4 ETO33649.1 - 0.0087 15.8 4.2 0.79 9.4 0.4 2.6 1 1 1 2 2 2 2 Uncharacterised conserved protein HEAT PF02985.17 ETO33649.1 - 0.013 15.5 0.2 39 4.6 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat Pox_C7_F8A PF03287.9 ETO33649.1 - 0.02 14.5 2.4 0.044 13.5 1.6 1.6 1 1 0 1 1 1 0 Poxvirus C7/F8A protein Cystatin PF00031.16 ETO33649.1 - 0.027 14.6 4.4 4 7.6 0.1 3.1 3 0 0 3 3 3 0 Cystatin domain MA3 PF02847.12 ETO33649.1 - 0.031 13.9 6.7 0.077 12.6 1.7 3.0 1 1 3 4 4 4 0 MA3 domain Polysacc_deac_1 PF01522.16 ETO33649.1 - 0.052 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide deacetylase MazG PF03819.12 ETO33649.1 - 0.077 12.9 1.3 8.5 6.4 0.1 3.0 3 0 0 3 3 3 0 MazG nucleotide pyrophosphohydrolase domain DUF1018 PF06252.7 ETO33649.1 - 0.078 13.4 0.6 15 6.1 0.0 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF1018) IPK PF03770.11 ETO33649.1 - 0.099 12.2 3.0 0.18 11.4 2.1 1.5 1 1 0 1 1 1 0 Inositol polyphosphate kinase Imm42 PF15601.1 ETO33649.1 - 0.1 12.0 0.6 0.37 10.2 0.2 2.2 1 1 1 2 2 2 0 Immunity protein 42 EAL PF00563.15 ETO33649.1 - 0.1 12.0 1.4 0.18 11.2 1.0 1.4 1 1 0 1 1 1 0 EAL domain MKT1_N PF12247.3 ETO33649.1 - 0.12 12.7 0.6 2.4 8.5 0.2 2.4 1 1 1 2 2 2 0 Temperature dependent protein affecting M2 dsRNA replication DERM PF14704.1 ETO33649.1 - 0.17 11.8 2.1 0.27 11.2 1.0 1.5 1 1 0 1 1 1 0 Dermatopontin TAP_C PF03943.8 ETO33649.1 - 0.3 10.5 3.6 3.4 7.1 0.3 2.7 2 1 0 2 2 2 0 TAP C-terminal domain C_GCAxxG_C_C PF09719.5 ETO33649.1 - 0.44 10.3 2.1 0.73 9.6 0.9 1.9 1 1 1 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) ENTH PF01417.15 ETO33649.1 - 0.47 10.3 7.4 0.6 9.9 2.3 2.2 1 1 1 2 2 2 0 ENTH domain MMS19_C PF12460.3 ETO33649.1 - 0.67 8.6 6.7 0.99 8.0 4.0 1.7 1 1 1 2 2 2 0 RNAPII transcription regulator C-terminal Syja_N PF02383.13 ETO33649.1 - 5.4 5.6 10.5 2.4 6.8 0.4 2.6 1 1 2 3 3 3 0 SacI homology domain Effector_1 PF04518.7 ETO33650.1 - 0.16 10.9 5.2 0.19 10.6 3.6 1.0 1 0 0 1 1 1 0 Effector from type III secretion system Toxin_39 PF15500.1 ETO33650.1 - 0.61 10.2 4.0 11 6.2 0.1 2.3 1 1 1 2 2 2 0 Putative RNase-like toxin DUF4407 PF14362.1 ETO33650.1 - 1 8.2 3.4 1.5 7.7 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.10 ETO33650.1 - 1.8 8.1 10.2 7 6.2 7.0 1.9 1 1 0 1 1 1 0 Septum formation initiator DUF1843 PF08898.5 ETO33650.1 - 1.9 8.6 4.8 1.8 8.6 1.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1843) Myb_CC_LHEQLE PF14379.1 ETO33650.1 - 2.9 7.5 11.7 1.3 8.6 4.1 2.7 2 1 0 3 3 3 0 MYB-CC type transfactor, LHEQLE motif G-gamma PF00631.17 ETO33650.1 - 5 6.9 7.6 1.3 8.8 1.2 2.9 2 1 1 3 3 3 0 GGL domain Filament PF00038.16 ETO33653.1 - 0.0037 16.7 26.0 0.0046 16.4 18.0 1.1 1 0 0 1 1 1 1 Intermediate filament protein CCDC155 PF14662.1 ETO33653.1 - 0.2 11.2 27.0 1.1 8.8 18.7 2.0 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 Reo_sigmaC PF04582.7 ETO33653.1 - 0.33 10.1 5.3 0.17 11.0 1.3 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 ETO33653.1 - 1.7 8.4 32.7 0.43 10.3 15.9 3.0 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein YscO PF07321.7 ETO33653.1 - 2.3 8.0 29.1 0.56 10.0 16.5 2.1 1 1 1 2 2 2 0 Type III secretion protein YscO Tropomyosin_1 PF12718.2 ETO33653.1 - 3 7.6 31.7 0.27 11.0 14.2 2.9 1 1 0 2 2 2 0 Tropomyosin like Imm46 PF15585.1 ETO33653.1 - 4.8 7.2 8.2 0.89 9.6 1.9 2.3 1 1 1 2 2 2 0 Immunity protein 46 WD40 PF00400.27 ETO33654.1 - 2.6e-41 138.0 9.8 1.1e-10 40.9 0.0 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO33654.1 - 8e-07 27.5 2.4 0.0069 14.5 0.0 3.6 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Peptidase_S55 PF05580.7 ETO33654.1 - 0.038 13.4 2.3 1.1 8.6 0.0 2.3 1 1 1 2 2 2 0 SpoIVB peptidase S55 HSP70 PF00012.15 ETO33655.1 - 1.7e-17 62.6 5.5 8.5e-11 40.4 2.3 2.0 1 1 1 2 2 2 2 Hsp70 protein Filament PF00038.16 ETO33655.1 - 0.0056 16.1 1.1 0.0071 15.8 0.8 1.1 1 0 0 1 1 1 1 Intermediate filament protein Terminase_4 PF05119.7 ETO33655.1 - 0.03 14.4 0.6 0.19 11.8 0.1 2.1 1 1 1 2 2 2 0 Phage terminase, small subunit AKNA PF12443.3 ETO33655.1 - 0.086 12.8 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 AT-hook-containing transcription factor EF-hand_7 PF13499.1 ETO33656.1 - 6.4e-07 29.4 1.0 7.2e-05 22.8 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 ETO33656.1 - 7.3e-07 28.5 1.9 0.00022 20.8 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 ETO33656.1 - 4.9e-06 25.4 0.5 0.00012 21.0 0.1 2.6 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 ETO33656.1 - 0.00045 19.4 0.4 0.0031 16.7 0.1 2.3 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 ETO33656.1 - 0.00088 18.8 0.1 0.0023 17.5 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain pair Tetraspannin PF00335.15 ETO33656.1 - 0.91 8.7 4.4 2.7 7.1 3.1 1.9 1 0 0 1 1 1 0 Tetraspanin family API5 PF05918.6 ETO33657.1 - 0.052 12.0 2.6 0.085 11.3 1.8 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) p450 PF00067.17 ETO33658.1 - 1.1e-39 136.3 0.0 1.3e-39 136.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Y_phosphatase2 PF03162.8 ETO33659.1 - 0.015 14.6 0.2 0.017 14.5 0.1 1.1 1 0 0 1 1 1 0 Tyrosine phosphatase family LRR_4 PF12799.2 ETO33660.1 - 2.6e-09 36.5 11.1 1.1e-08 34.5 3.5 3.5 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETO33660.1 - 1.2e-05 24.6 1.5 0.36 11.0 0.1 3.5 2 0 0 2 2 2 2 Leucine Rich Repeat LRR_8 PF13855.1 ETO33660.1 - 0.0014 18.3 11.1 0.0041 16.8 5.0 3.1 2 1 0 2 2 2 1 Leucine rich repeat LRR_7 PF13504.1 ETO33660.1 - 0.0016 18.2 4.5 1 9.8 0.0 3.8 3 0 0 3 3 3 2 Leucine rich repeat Voldacs PF03517.8 ETO33660.1 - 0.026 14.3 0.2 0.063 13.1 0.0 1.7 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling EF1G PF00647.14 ETO33660.1 - 0.12 12.0 2.1 0.13 11.9 0.2 2.0 2 0 0 2 2 2 0 Elongation factor 1 gamma, conserved domain LRR_6 PF13516.1 ETO33660.1 - 0.2 11.8 8.4 2.8 8.2 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich repeat dCMP_cyt_deam_1 PF00383.17 ETO33661.1 - 5.8e-27 93.3 0.0 1.1e-26 92.4 0.0 1.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 ETO33661.1 - 0.02 14.4 0.2 0.034 13.7 0.1 1.3 1 0 0 1 1 1 0 APOBEC-like N-terminal domain CAP_GLY PF01302.20 ETO33662.1 - 0.0002 21.0 0.2 0.00029 20.4 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain FERM_C PF09380.5 ETO33662.1 - 0.042 14.0 0.2 0.068 13.3 0.1 1.3 1 0 0 1 1 1 0 FERM C-terminal PH-like domain DUF3754 PF12576.3 ETO33663.1 - 7.9e-12 45.0 0.0 1.6e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3754) WD40 PF00400.27 ETO33663.1 - 0.00022 21.0 0.2 0.00072 19.3 0.2 2.0 1 0 0 1 1 1 1 WD domain, G-beta repeat DUF3435 PF11917.3 ETO33663.1 - 0.041 12.5 0.0 0.061 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) WD40 PF00400.27 ETO33664.1 - 1.4e-35 119.8 6.9 2.5e-11 43.0 0.0 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO33664.1 - 8e-09 34.1 3.4 3.2e-05 22.2 0.2 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO33664.1 - 0.0012 18.2 3.8 0.021 14.1 0.3 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4221) DUF3601 PF12208.3 ETO33664.1 - 0.0048 16.7 0.0 0.011 15.6 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3601) Kelch_6 PF13964.1 ETO33664.1 - 0.057 13.6 1.6 20 5.5 0.2 3.3 3 1 0 3 3 3 0 Kelch motif Cu-oxidase_2 PF07731.9 ETO33664.1 - 0.066 12.7 0.1 0.078 12.4 0.1 1.2 1 0 0 1 1 1 0 Multicopper oxidase YopX PF09643.5 ETO33664.1 - 0.068 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 YopX protein DUF1914 PF08932.5 ETO33664.1 - 0.11 12.4 0.8 2 8.4 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1914) Plasmodium_Vir PF05795.6 ETO33665.1 - 0.019 14.2 1.9 0.02 14.1 1.3 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Alveol-reg_P311 PF11092.3 ETO33665.1 - 0.019 14.9 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 Neuronal protein 3.1 (p311) Gti1_Pac2 PF09729.4 ETO33665.1 - 3 7.6 8.6 4.9 6.9 5.9 1.4 1 1 0 1 1 1 0 Gti1/Pac2 family Ank_4 PF13637.1 ETO33666.1 - 1.3e-14 54.2 2.4 1.4e-06 28.6 0.1 2.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO33666.1 - 2e-13 50.1 0.1 6.1e-08 32.6 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO33666.1 - 7e-13 48.7 0.2 6.4e-07 29.6 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETO33666.1 - 2.7e-09 36.3 0.1 0.0011 18.7 0.0 3.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 ETO33666.1 - 2.6e-08 33.3 0.1 0.047 13.9 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Mito_carr PF00153.22 ETO33668.1 - 4.7e-25 87.1 0.0 2.3e-17 62.4 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Bromodomain PF00439.20 ETO33670.1 - 9.1e-19 67.1 0.1 6.3e-18 64.4 0.0 2.3 3 0 0 3 3 3 1 Bromodomain DUF1631 PF07793.6 ETO33670.1 - 0.0078 14.4 0.1 0.011 13.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1631) DUF1411 PF07199.6 ETO33670.1 - 0.11 11.9 0.9 0.32 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1411) Glyoxalase_2 PF12681.2 ETO33671.1 - 7e-11 42.6 0.0 9.5e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 ETO33671.1 - 8.9e-09 35.3 0.1 4.2e-08 33.2 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 ETO33671.1 - 0.00056 19.8 0.0 0.00082 19.3 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 ETO33671.1 - 0.02 14.8 0.0 0.03 14.2 0.0 1.6 1 1 0 1 1 1 0 Glyoxalase-like domain OST-HTH PF12872.2 ETO33672.1 - 3.7e-07 29.8 0.6 0.00073 19.3 0.0 2.9 3 0 0 3 3 3 2 OST-HTH/LOTUS domain Cucumo_2B PF03263.8 ETO33672.1 - 0.22 11.8 1.0 1.7 8.9 0.7 2.4 1 1 0 1 1 1 0 Cucumovirus protein 2B PP_M1 PF03012.9 ETO33674.1 - 0.063 12.6 3.3 0.074 12.3 2.3 1.0 1 0 0 1 1 1 0 Phosphoprotein API5 PF05918.6 ETO33676.1 - 0.0077 14.7 2.1 0.013 13.9 1.4 1.4 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) WD40 PF00400.27 ETO33677.1 - 2.3e-08 33.6 3.5 0.0029 17.4 0.1 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat eIF2A PF08662.6 ETO33677.1 - 0.018 14.7 0.0 1.1 8.9 0.0 2.8 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 ETO33677.1 - 0.1 11.3 0.0 2.6 6.7 0.0 2.1 2 0 0 2 2 2 0 Coatomer WD associated region WD40 PF00400.27 ETO33678.1 - 0.0042 16.9 0.4 0.0097 15.7 0.0 1.8 2 0 0 2 2 2 1 WD domain, G-beta repeat Phage_Coat_A PF05357.8 ETO33679.1 - 0.037 13.6 0.8 7.4 6.2 0.1 2.1 2 0 0 2 2 2 0 Phage Coat Protein A Fe-ADH PF00465.14 ETO33680.1 - 0.049 12.2 0.8 0.072 11.7 0.6 1.2 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase DDE_Tnp_IS1595 PF12762.2 ETO33680.1 - 0.57 10.0 13.6 2 8.2 9.1 2.3 1 1 0 1 1 1 0 ISXO2-like transposase domain DUF4551 PF15087.1 ETO33680.1 - 0.78 8.0 21.4 0.95 7.7 14.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) LCM PF04072.9 ETO33681.1 - 6.1e-16 58.5 0.0 1.5e-15 57.2 0.0 1.6 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase SAM_2 PF07647.12 ETO33683.1 - 1.5e-09 37.5 0.2 3.5e-09 36.3 0.2 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO33683.1 - 6.1e-09 35.9 0.5 1.4e-08 34.8 0.4 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 ETO33683.1 - 0.013 15.2 0.7 0.053 13.2 0.5 2.1 1 1 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain DUF1192 PF06698.6 ETO33683.1 - 0.037 13.8 4.8 3.2 7.6 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) DUF3584 PF12128.3 ETO33683.1 - 0.24 8.7 36.0 0.3 8.3 25.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spore_YhaL PF14147.1 ETO33683.1 - 0.6 9.5 10.4 1 8.8 0.0 2.9 3 0 0 3 3 3 0 Sporulation protein YhaL LuxS PF02664.10 ETO33683.1 - 2.9 7.4 6.4 16 4.9 0.8 2.5 2 0 0 2 2 2 0 S-Ribosylhomocysteinase (LuxS) Kinesin PF00225.18 ETO33684.1 - 1.7e-102 342.5 1.8 4.5e-102 341.1 1.2 1.7 1 1 0 1 1 1 1 Kinesin motor domain AKNA PF12443.3 ETO33684.1 - 0.0011 18.9 0.8 0.0037 17.2 0.3 2.0 2 0 0 2 2 2 1 AT-hook-containing transcription factor 4HBT_2 PF13279.1 ETO33685.1 - 1.2e-17 64.4 0.5 1.7e-17 64.0 0.3 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 ETO33685.1 - 6.2e-06 26.2 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily NAAA-beta PF15508.1 ETO33686.1 - 5.8e-18 65.0 0.1 5.8e-18 65.0 0.1 3.1 3 0 0 3 3 3 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase CBAH PF02275.13 ETO33686.1 - 0.00035 20.1 0.0 0.00076 18.9 0.0 1.6 1 0 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family BRX_N PF13713.1 ETO33686.1 - 6.8 6.2 10.1 13 5.3 0.2 3.7 4 0 0 4 4 4 0 Transcription factor BRX N-terminal domain CENP-Q PF13094.1 ETO33686.1 - 7 6.6 30.9 5 7.1 19.5 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit CENP-F_leu_zip PF10473.4 ETO33686.1 - 9.4 6.0 37.4 1.1 9.1 9.0 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FokI_N PF02981.10 ETO33687.1 - 0.45 10.1 2.5 0.81 9.2 0.3 2.2 2 0 0 2 2 2 0 Restriction endonuclease FokI, recognition domain ROS_MUCR PF05443.6 ETO33688.1 - 0.094 12.4 5.0 0.26 11.0 0.9 2.3 1 1 1 2 2 2 0 ROS/MUCR transcriptional regulator protein Endotoxin_N PF03945.9 ETO33688.1 - 0.19 11.0 8.5 0.34 10.2 5.9 1.4 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain FlxA PF14282.1 ETO33688.1 - 0.22 11.5 40.8 0.098 12.6 7.9 2.3 1 1 1 2 2 2 0 FlxA-like protein Exonuc_VII_L PF02601.10 ETO33688.1 - 0.36 9.9 14.0 0.53 9.4 9.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Pro-rich_19 PF15455.1 ETO33688.1 - 1.1 8.2 3.9 0.29 10.1 0.0 1.9 3 0 0 3 3 3 0 Proline-rich 19 DUF724 PF05266.9 ETO33688.1 - 1.1 8.8 17.0 2.3 7.7 11.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4407 PF14362.1 ETO33688.1 - 3.4 6.5 12.4 4.7 6.0 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3373 PF11853.3 ETO33688.1 - 4.9 5.5 9.4 7.8 4.9 6.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Phage_GP20 PF06810.6 ETO33688.1 - 7.4 5.9 31.0 7.9 5.8 5.4 2.6 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF1528 PF07515.6 ETO33689.1 - 0.011 15.7 0.8 0.12 12.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1528) DUF3043 PF11241.3 ETO33689.1 - 2.7 7.5 6.5 0.45 10.0 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3043) DEP PF00610.16 ETO33691.1 - 1.2e-05 24.9 0.0 2.7e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CotJA PF11007.3 ETO33691.1 - 0.026 14.1 1.3 0.31 10.7 0.0 2.6 2 0 0 2 2 2 0 Spore coat associated protein JA (CotJA) TLP-20 PF06088.6 ETO33692.1 - 0.011 15.3 5.4 0.02 14.5 3.8 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF1510 PF07423.6 ETO33692.1 - 0.14 11.5 9.4 0.18 11.1 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SID-1_RNA_chan PF13965.1 ETO33692.1 - 0.36 8.9 1.9 0.45 8.6 1.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 AIF_C PF14721.1 ETO33692.1 - 0.54 10.4 5.3 0.86 9.8 3.7 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SAPS PF04499.10 ETO33692.1 - 0.81 8.2 7.6 4.7 5.7 4.3 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein SecD-TM1 PF13721.1 ETO33693.1 - 0.023 14.9 0.0 0.069 13.4 0.0 1.9 1 0 0 1 1 1 0 SecD export protein N-terminal TM region Voltage_CLC PF00654.15 ETO33693.1 - 0.12 11.4 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Voltage gated chloride channel OAD_gamma PF04277.8 ETO33693.1 - 0.41 11.0 3.8 37 4.7 0.1 3.7 4 0 0 4 4 4 0 Oxaloacetate decarboxylase, gamma chain SPATA19 PF15212.1 ETO33693.1 - 0.46 10.5 5.0 6.9 6.7 1.6 2.9 2 1 1 3 3 3 0 Spermatogenesis-associated protein 19, mitochondrial 7tm_1 PF00001.16 ETO33693.1 - 2.8 7.0 7.8 82 2.1 5.2 2.4 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Tubulin PF00091.20 ETO33694.1 - 2.5e-64 217.0 0.1 3.8e-64 216.4 0.1 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO33694.1 - 4.2e-29 101.1 0.0 9.4e-29 100.0 0.0 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 ETO33694.1 - 7.1e-06 26.0 0.0 1.5e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 ETO33694.1 - 0.0015 18.0 0.0 0.0029 17.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.1 ETO33694.1 - 0.013 14.5 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Melibiase PF02065.13 ETO33695.1 - 1.3e-22 80.0 2.1 5.4e-17 61.5 0.0 2.2 2 0 0 2 2 2 2 Melibiase ACBP PF00887.14 ETO33697.1 - 3.7e-14 52.1 0.1 1.2e-13 50.4 0.1 1.9 1 1 1 2 2 2 1 Acyl CoA binding protein EF-hand_6 PF13405.1 ETO33698.1 - 1.3e-07 30.9 4.0 0.0083 15.9 0.0 3.8 3 1 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 ETO33698.1 - 8.4e-06 24.7 5.1 0.0012 18.0 0.0 3.8 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.1 ETO33698.1 - 5e-05 23.3 2.9 8.7e-05 22.5 0.4 2.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 ETO33698.1 - 0.00064 18.9 5.4 0.0087 15.3 0.0 3.7 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.1 ETO33698.1 - 0.0029 17.1 0.7 0.013 15.0 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair Eno-Rase_FAD_bd PF07055.7 ETO33698.1 - 0.033 14.1 3.4 0.74 9.8 0.2 2.4 2 0 0 2 2 2 0 Enoyl reductase FAD binding domain DUF848 PF05852.6 ETO33698.1 - 0.044 13.6 0.2 0.044 13.6 0.2 1.5 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Miro PF08477.8 ETO33698.1 - 0.071 13.6 0.3 8.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein FadA PF09403.5 ETO33698.1 - 0.58 10.1 5.4 2.8 7.9 0.5 2.2 2 0 0 2 2 2 0 Adhesion protein FadA Tudor-knot PF11717.3 ETO33699.1 - 0.00084 18.9 2.5 0.00084 18.9 1.7 2.6 3 0 0 3 3 3 1 RNA binding activity-knot of a chromodomain Mitofilin PF09731.4 ETO33699.1 - 1.4 7.4 17.7 2.3 6.7 12.3 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CD52 PF15116.1 ETO33702.1 - 7.5 6.4 6.8 33 4.3 2.5 2.5 2 0 0 2 2 2 0 CAMPATH-1 antigen PH_8 PF15409.1 ETO33703.1 - 0.0035 17.3 0.0 0.0098 15.9 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 ETO33703.1 - 0.02 15.1 8.5 0.055 13.7 5.9 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain PH PF00169.24 ETO33703.1 - 0.3 11.2 9.1 1.4 9.1 6.3 2.2 1 1 0 1 1 1 0 PH domain SOBP PF15279.1 ETO33703.1 - 0.92 9.8 12.4 1.1 9.5 8.6 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4407 PF14362.1 ETO33703.1 - 1.4 7.7 5.6 1.7 7.5 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YscJ_FliF_C PF08345.6 ETO33703.1 - 3 7.7 25.4 0.38 10.7 14.5 1.7 1 1 1 2 2 2 0 Flagellar M-ring protein C-terminal LRR_6 PF13516.1 ETO33704.1 - 0.0023 17.8 0.1 0.0023 17.8 0.0 3.5 5 0 0 5 5 5 1 Leucine Rich repeat LRR_4 PF12799.2 ETO33704.1 - 0.003 17.1 0.4 0.015 14.9 0.1 2.2 1 1 1 2 2 2 1 Leucine Rich repeats (2 copies) Trp_dioxygenase PF03301.8 ETO33704.1 - 0.097 11.7 0.2 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 Tryptophan 2,3-dioxygenase DUF4476 PF14771.1 ETO33704.1 - 0.21 11.6 1.9 3.1 7.9 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4476) Ins_beta PF03488.9 ETO33704.1 - 0.39 10.5 2.1 1.9 8.3 0.1 2.4 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type LRR_1 PF00560.28 ETO33704.1 - 3.8 7.9 0.0 3.8 7.9 0.0 3.5 4 1 0 4 4 4 0 Leucine Rich Repeat ALIX_LYPXL_bnd PF13949.1 ETO33705.1 - 4.8e-37 127.5 11.1 5.3e-22 78.1 3.4 3.6 2 1 2 4 4 4 2 ALIX V-shaped domain binding to HIV Plasmid_stabil PF05016.9 ETO33705.1 - 0.11 12.9 0.4 12 6.3 0.1 2.7 2 0 0 2 2 2 0 Plasmid stabilisation system protein DUF2161 PF09929.4 ETO33705.1 - 0.13 12.1 0.5 0.35 10.8 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2161) Laminin_II PF06009.7 ETO33705.1 - 0.34 10.6 6.8 0.11 12.3 0.6 2.9 2 1 1 3 3 3 0 Laminin Domain II DUF883 PF05957.8 ETO33705.1 - 0.73 10.2 6.1 0.56 10.6 0.7 3.1 2 1 3 5 5 5 0 Bacterial protein of unknown function (DUF883) Acyl-CoA_dh_C PF12806.2 ETO33705.1 - 3.4 7.5 5.5 18 5.2 0.4 2.7 3 0 0 3 3 3 0 Acetyl-CoA dehydrogenase C-terminal like Daxx PF03344.10 ETO33706.1 - 0.006 15.1 29.5 0.0076 14.7 20.4 1.1 1 0 0 1 1 1 1 Daxx Family RskA PF10099.4 ETO33706.1 - 0.013 15.2 2.7 0.013 15.2 1.9 2.0 2 1 1 3 3 3 0 Anti-sigma-K factor rskA Nop14 PF04147.7 ETO33706.1 - 0.035 12.0 28.0 0.046 11.6 19.4 1.2 1 0 0 1 1 1 0 Nop14-like family Utp14 PF04615.8 ETO33706.1 - 0.06 11.5 29.6 0.079 11.1 20.5 1.1 1 0 0 1 1 1 0 Utp14 protein CDC45 PF02724.9 ETO33706.1 - 0.42 8.6 23.4 0.59 8.0 16.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 ETO33706.1 - 1.5 6.3 17.5 2.2 5.9 12.2 1.2 1 0 0 1 1 1 0 Ycf1 PLRV_ORF5 PF01690.12 ETO33706.1 - 1.8 7.6 24.2 3 6.8 16.8 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SGT1 PF07093.6 ETO33706.1 - 5.4 5.2 31.7 7.3 4.8 22.0 1.1 1 0 0 1 1 1 0 SGT1 protein Hid1 PF12722.2 ETO33706.1 - 5.8 4.4 25.2 9.4 3.7 17.5 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.17 ETO33706.1 - 6.6 5.6 13.9 2.7 6.9 7.4 2.1 2 1 0 2 2 2 0 ZIP Zinc transporter WD40 PF00400.27 ETO33707.1 - 2.4e-56 185.7 30.1 5.3e-12 45.1 0.1 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO33707.1 - 3.9e-08 31.8 2.8 0.023 12.8 0.6 4.6 1 1 3 4 4 4 4 Nucleoporin Nup120/160 HAD PF12710.2 ETO33707.1 - 0.076 13.1 0.3 28 4.8 0.1 3.7 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Peptidase_C14 PF00656.17 ETO33708.1 - 7.9e-09 35.5 0.9 1.7e-08 34.4 0.6 1.5 1 0 0 1 1 1 1 Caspase domain Suc_Fer-like PF06999.7 ETO33708.1 - 0.019 14.9 0.2 0.019 14.9 0.1 3.4 2 1 0 3 3 3 0 Sucrase/ferredoxin-like WD40 PF00400.27 ETO33711.1 - 3.4e-33 112.3 11.2 7.9e-11 41.4 0.0 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO33711.1 - 3.5e-08 32.0 0.8 0.017 13.3 0.0 3.1 2 1 0 3 3 3 3 Nucleoporin Nup120/160 DUF2559 PF10832.3 ETO33711.1 - 8.8 6.2 6.5 16 5.3 0.1 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2559) DUF1836 PF08876.6 ETO33712.1 - 0.1 12.3 2.6 0.12 12.1 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1836) MRP-S26 PF14943.1 ETO33713.1 - 1.2 8.7 29.8 1.4 8.4 20.7 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Gag_spuma PF03276.9 ETO33713.1 - 4.4 5.5 12.3 4.6 5.4 8.5 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Kelch_1 PF01344.20 ETO33714.1 - 4.3e-07 29.3 0.2 2.7e-05 23.6 0.2 2.3 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.10 ETO33714.1 - 3.7e-05 23.3 0.2 0.059 13.1 0.2 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.1 ETO33714.1 - 0.00044 20.1 0.7 0.036 14.0 0.1 2.5 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 ETO33714.1 - 0.00082 19.4 1.6 0.0047 17.0 0.5 2.1 1 1 1 2 2 2 1 Kelch motif Kelch_4 PF13418.1 ETO33714.1 - 0.0047 16.6 0.1 0.047 13.4 0.0 2.1 1 1 1 2 2 2 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO33714.1 - 0.011 15.8 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 Galactose oxidase, central domain DcpS_C PF11969.3 ETO33714.1 - 0.12 12.6 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding DUF2414 PF10309.4 ETO33714.1 - 0.13 11.9 0.7 0.26 11.0 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2414) Baculo_DNA_bind PF04786.7 ETO33715.1 - 0.074 12.1 0.2 0.08 12.0 0.1 1.0 1 0 0 1 1 1 0 ssDNA binding protein WD40 PF00400.27 ETO33716.1 - 7.3e-24 82.7 12.2 2.8e-08 33.3 0.6 4.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO33716.1 - 0.001 17.3 0.1 3.6 5.6 0.0 3.1 3 0 0 3 3 3 3 Nucleoporin Nup120/160 DUF912 PF06024.7 ETO33717.1 - 0.023 14.7 0.9 0.023 14.7 0.6 3.5 3 1 1 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Menin PF05053.8 ETO33717.1 - 0.1 10.7 1.2 0.14 10.3 0.8 1.1 1 0 0 1 1 1 0 Menin DUF3260 PF11658.3 ETO33717.1 - 0.12 10.5 3.6 0.028 12.5 0.3 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3260) Secretin_N_2 PF07655.8 ETO33717.1 - 0.5 10.7 12.7 0.92 9.9 8.8 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain O-FucT PF10250.4 ETO33720.1 - 0.014 14.5 0.0 0.029 13.4 0.0 1.5 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase Spc24 PF08286.6 ETO33722.1 - 0.0084 15.7 2.4 0.033 13.8 1.7 2.0 1 0 0 1 1 1 1 Spc24 subunit of Ndc80 zf-C3HC4_2 PF13923.1 ETO33722.1 - 0.017 15.1 3.4 0.14 12.2 2.4 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF948 PF06103.6 ETO33722.1 - 0.022 14.6 0.5 0.047 13.5 0.4 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) SID-1_RNA_chan PF13965.1 ETO33722.1 - 0.023 12.8 3.0 0.028 12.6 2.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2968 PF11180.3 ETO33722.1 - 0.031 13.6 3.1 0.061 12.7 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DivIC PF04977.10 ETO33722.1 - 0.25 10.8 2.9 0.74 9.3 2.0 1.8 1 0 0 1 1 1 0 Septum formation initiator XhlA PF10779.4 ETO33722.1 - 3.2 7.7 7.0 0.59 10.0 1.3 2.3 2 0 0 2 2 2 0 Haemolysin XhlA FlxA PF14282.1 ETO33722.1 - 5.8 6.9 10.8 0.39 10.6 3.5 2.0 2 0 0 2 2 2 0 FlxA-like protein Cep57_CLD_2 PF14197.1 ETO33722.1 - 6 6.8 9.8 2.9 7.9 1.8 3.1 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 ThylakoidFormat PF11264.3 ETO33722.1 - 8.4 5.9 10.2 3.2 7.3 3.3 2.1 1 1 1 2 2 2 0 Thylakoid formation protein WD40 PF00400.27 ETO33723.1 - 0.0003 20.5 0.5 0.00055 19.7 0.4 1.5 1 0 0 1 1 1 1 WD domain, G-beta repeat WD40 PF00400.27 ETO33724.1 - 9.9e-61 199.6 13.8 5.3e-13 48.2 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO33724.1 - 2.9e-08 32.3 5.0 0.043 11.9 0.2 4.5 2 2 3 5 5 5 3 Nucleoporin Nup120/160 Kelch_1 PF01344.20 ETO33724.1 - 3.1e-07 29.8 4.9 6.1e-05 22.4 0.2 4.3 4 0 0 4 4 4 1 Kelch motif Cytochrom_D1 PF02239.11 ETO33724.1 - 0.00032 19.0 1.6 0.044 12.0 0.0 3.3 1 1 4 5 5 5 2 Cytochrome D1 heme domain Kelch_4 PF13418.1 ETO33724.1 - 0.00055 19.6 0.1 1.4 8.7 0.0 4.0 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO33724.1 - 0.00079 19.0 3.9 0.94 9.3 0.1 5.3 6 0 0 6 6 6 1 Kelch motif Kelch_5 PF13854.1 ETO33724.1 - 0.0014 18.5 0.6 2.4 8.2 0.2 4.6 5 0 0 5 5 5 1 Kelch motif PD40 PF07676.7 ETO33724.1 - 0.009 15.6 1.8 2.8 7.7 0.1 3.9 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat DNA_pol3_delta PF06144.8 ETO33724.1 - 0.016 14.7 0.1 0.052 13.0 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase III, delta subunit Kelch_3 PF13415.1 ETO33724.1 - 0.094 12.9 0.3 10 6.4 0.1 3.9 4 0 0 4 4 4 0 Galactose oxidase, central domain WD40 PF00400.27 ETO33725.1 - 7.7e-61 199.9 28.4 2.5e-11 42.9 0.1 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO33725.1 - 2.9e-09 35.6 7.5 0.13 10.4 0.1 5.0 1 1 4 5 5 5 5 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO33725.1 - 0.1 11.9 8.8 0.19 11.0 2.7 2.9 1 1 1 3 3 3 0 Domain of unknown function (DUF4221) CblD PF07434.6 ETO33725.1 - 0.36 9.4 6.3 0.29 9.7 1.1 2.3 2 0 0 2 2 2 0 CblD like pilus biogenesis initiator zf-C3HC4_2 PF13923.1 ETO33726.1 - 0.0039 17.1 2.9 0.021 14.8 2.0 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1796 PF08795.5 ETO33726.1 - 0.006 16.2 4.4 0.16 11.5 0.1 2.4 2 0 0 2 2 2 2 Putative papain-like cysteine peptidase (DUF1796) DUF848 PF05852.6 ETO33726.1 - 0.086 12.6 12.1 0.1 12.4 6.3 2.7 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF1003 PF06210.6 ETO33726.1 - 1.1 9.2 5.9 0.29 11.0 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1003) Cys_knot PF00007.17 ETO33726.1 - 3.1 7.9 12.3 0.35 10.9 3.6 2.4 2 1 1 3 3 3 0 Cystine-knot domain NACHT PF05729.7 ETO33727.1 - 2.2e-12 46.9 0.0 9e-12 44.9 0.0 2.0 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 ETO33727.1 - 0.00097 18.0 0.3 0.0036 16.1 0.2 2.0 1 1 0 1 1 1 1 NB-ARC domain Mg_chelatase PF01078.16 ETO33727.1 - 0.0054 15.9 0.0 0.0094 15.1 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 ETO33727.1 - 0.0059 16.7 0.0 0.045 13.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETO33727.1 - 0.014 15.1 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 ETO33727.1 - 0.016 15.2 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 ETO33727.1 - 0.017 14.5 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF992 PF06186.6 ETO33727.1 - 0.061 12.6 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF992) AAA_18 PF13238.1 ETO33727.1 - 0.42 10.9 0.0 0.42 10.9 0.0 3.4 3 3 1 4 4 4 0 AAA domain Synaptobrevin PF00957.16 ETO33728.1 - 0.21 11.2 3.2 0.15 11.6 0.4 1.9 2 0 0 2 2 2 0 Synaptobrevin ABC_tran_2 PF12848.2 ETO33728.1 - 1.3 8.9 4.4 0.3 10.9 0.6 1.7 2 0 0 2 2 2 0 ABC transporter FlaC_arch PF05377.6 ETO33728.1 - 1.8 8.4 4.9 9.6 6.1 3.4 2.1 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) WD40 PF00400.27 ETO33729.1 - 5.5e-29 98.9 12.5 7.6e-11 41.4 1.2 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO33729.1 - 0.00016 19.9 0.2 0.031 12.4 0.0 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO33729.1 - 0.29 9.8 6.2 3.5 6.2 0.0 2.4 1 1 1 2 2 2 0 Nup133 N terminal like Carboxyl_trans PF01039.17 ETO33731.1 - 1.3e-22 79.8 0.0 1.6e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Ank_2 PF12796.2 ETO33732.1 - 1.5e-12 47.6 4.6 6e-05 23.3 0.1 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO33732.1 - 2.1e-08 34.1 3.5 0.0032 17.6 0.0 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO33732.1 - 2.4e-07 31.0 0.6 0.1 13.1 0.0 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO33732.1 - 1.6e-06 27.7 3.7 0.55 10.6 0.1 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.25 ETO33732.1 - 2.1e-06 27.2 0.6 0.28 11.0 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat PhoQ_Sensor PF08918.5 ETO33732.1 - 0.013 15.0 0.6 0.34 10.3 0.0 2.3 2 1 0 2 2 2 0 PhoQ Sensor Thioredoxin_5 PF13743.1 ETO33732.1 - 0.029 13.9 0.2 0.7 9.4 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin Methyltransf_12 PF08242.7 ETO33732.1 - 0.034 14.6 3.0 0.12 12.8 1.1 2.3 2 1 0 2 2 2 0 Methyltransferase domain FAM176 PF14851.1 ETO33732.1 - 0.039 13.6 0.2 0.056 13.1 0.1 1.2 1 0 0 1 1 1 0 FAM176 family DUF2457 PF10446.4 ETO33732.1 - 0.095 11.4 4.8 0.13 10.9 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF3245 PF11595.3 ETO33732.1 - 0.26 11.5 3.3 0.41 10.9 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) PBP1_TM PF14812.1 ETO33732.1 - 0.38 11.1 3.8 0.75 10.1 2.6 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Reticulon PF02453.12 ETO33733.1 - 0.029 13.9 3.1 0.065 12.8 2.2 1.5 1 0 0 1 1 1 0 Reticulon BTP PF05232.7 ETO33734.1 - 0.59 9.9 0.1 0.59 9.9 0.1 3.2 3 1 0 3 3 3 0 Bacterial Transmembrane Pair family Cytochrom_B_N PF00033.14 ETO33734.1 - 1.2 8.4 12.4 7.4 5.8 8.6 2.0 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Ni_hydr_CYTB PF01292.15 ETO33734.1 - 3.1 7.1 10.4 0.12 11.7 2.1 2.0 1 1 0 2 2 2 0 Prokaryotic cytochrome b561 DUF1129 PF06570.6 ETO33734.1 - 4.3 6.6 9.3 0.25 10.6 2.0 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1129) Med3 PF11593.3 ETO33735.1 - 1 8.5 8.1 1.5 8.0 5.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal GOLD_2 PF13897.1 ETO33735.1 - 1.6 8.9 5.9 3.8 7.7 4.1 1.7 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking RR_TM4-6 PF06459.7 ETO33735.1 - 5.6 6.7 12.3 1.3 8.8 5.3 1.9 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Paf1 PF03985.8 ETO33735.1 - 9.4 4.8 17.0 15 4.2 11.8 1.3 1 0 0 1 1 1 0 Paf1 CobT PF06213.7 ETO33735.1 - 10 5.1 14.4 17 4.3 10.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Hydrolase_3 PF08282.7 ETO33736.1 - 0.038 13.5 0.0 0.082 12.4 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PA PF02225.17 ETO33736.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 PA domain PRKCSH_1 PF13015.1 ETO33737.1 - 0.049 13.1 0.0 0.28 10.6 0.0 1.9 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein WD40 PF00400.27 ETO33738.1 - 1.5e-58 192.7 25.0 2.1e-09 36.9 0.5 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO33738.1 - 2.6e-10 39.0 6.3 0.0052 14.9 0.0 4.8 1 1 3 5 5 5 5 Nucleoporin Nup120/160 CBS PF00571.23 ETO33739.1 - 7.7e-05 22.3 0.1 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 CBS domain Dimer_Tnp_Tn5 PF02281.11 ETO33740.1 - 0.44 10.6 2.2 0.33 11.0 0.3 1.7 2 0 0 2 2 2 0 Transposase Tn5 dimerisation domain NYD-SP28_assoc PF14775.1 ETO33740.1 - 0.48 10.1 10.6 3.3 7.4 0.9 2.6 2 0 0 2 2 2 0 Sperm tail C-terminal domain CRC_subunit PF08624.5 ETO33740.1 - 1.1 9.1 6.4 9 6.2 1.2 2.1 2 0 0 2 2 2 0 Chromatin remodelling complex Rsc7/Swp82 subunit DUF3347 PF11827.3 ETO33740.1 - 1.8 8.5 9.7 4.8 7.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) IMCp PF12314.3 ETO33740.1 - 2.1 8.5 7.9 0.65 10.1 3.2 1.9 1 1 1 2 2 2 0 Inner membrane complex protein DUF1043 PF06295.7 ETO33740.1 - 5.7 6.5 12.2 0.39 10.3 2.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) ERp29 PF07749.7 ETO33740.1 - 9.7 6.8 12.8 0.63 10.7 4.5 2.2 2 1 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain DUF4544 PF15077.1 ETO33741.1 - 0.031 13.8 0.7 0.038 13.5 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) NDT80_PhoG PF05224.7 ETO33741.1 - 0.055 13.4 0.9 0.065 13.2 0.6 1.2 1 0 0 1 1 1 0 NDT80 / PhoG like DNA-binding family DUF2180 PF09947.4 ETO33743.1 - 0.004 16.8 4.4 0.012 15.3 3.0 1.8 1 1 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2180) C1_2 PF03107.11 ETO33743.1 - 0.0099 15.9 3.6 0.03 14.4 2.5 1.9 1 0 0 1 1 1 1 C1 domain ZZ PF00569.12 ETO33743.1 - 0.12 11.9 4.1 0.58 9.7 2.9 2.1 1 1 0 1 1 1 0 Zinc finger, ZZ type C1_1 PF00130.17 ETO33743.1 - 0.14 11.8 1.4 0.35 10.6 1.0 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HypA PF01155.14 ETO33743.1 - 0.24 11.0 1.6 0.42 10.3 0.5 1.8 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 ETO33743.1 - 0.54 10.1 5.0 1.6 8.6 3.5 1.9 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 ETO33743.1 - 0.55 9.7 3.0 0.77 9.3 0.7 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-Di19 PF05605.7 ETO33743.1 - 0.63 10.2 5.0 0.38 10.8 2.0 1.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Alpha_kinase PF02816.13 ETO33744.1 - 6.6e-38 130.2 0.1 1.4e-37 129.2 0.1 1.6 1 0 0 1 1 1 1 Alpha-kinase family DUF3556 PF12077.3 ETO33744.1 - 0.068 11.1 0.1 0.096 10.6 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein of unknown function (DUF3556) AMP-binding PF00501.23 ETO33745.1 - 8.1e-30 103.5 0.0 6.7e-29 100.5 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETO33745.1 - 7.8e-09 36.3 0.0 1.5e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 ETO33746.1 - 3.5e-33 114.6 0.0 3.9e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Alpha_kinase PF02816.13 ETO33747.1 - 2e-29 102.6 0.4 3.4e-28 98.5 0.2 2.6 2 1 0 2 2 2 1 Alpha-kinase family FtsJ PF01728.14 ETO33748.1 - 6.1e-51 172.9 0.2 8.3e-51 172.5 0.1 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 ETO33748.1 - 0.057 14.0 0.0 0.23 12.0 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain TH1 PF04858.8 ETO33748.1 - 0.1 10.7 0.0 0.16 10.1 0.0 1.2 1 0 0 1 1 1 0 TH1 protein CbiA PF01656.18 ETO33748.1 - 0.13 11.7 0.7 0.35 10.2 0.5 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain OAF PF14941.1 ETO33749.1 - 0.079 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator, Out at first Ribosomal_S17 PF00366.15 ETO33751.1 - 4.7e-05 23.3 0.0 0.00018 21.4 0.0 2.1 1 0 0 1 1 1 1 Ribosomal protein S17 ApoL PF05461.6 ETO33751.1 - 0.043 13.0 3.3 0.065 12.4 2.3 1.2 1 0 0 1 1 1 0 Apolipoprotein L DUF1411 PF07199.6 ETO33751.1 - 0.088 12.2 1.6 0.11 11.9 0.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1411) PfkB PF00294.19 ETO33752.1 - 1.8e-14 53.5 0.1 2.8e-14 52.9 0.1 1.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase PfkB PF00294.19 ETO33753.1 - 3.7e-12 46.0 0.0 4.1e-12 45.8 0.0 1.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase DUF4569 PF15133.1 ETO33755.1 - 0.0035 16.7 0.7 0.0047 16.3 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4569) DUF1461 PF07314.6 ETO33755.1 - 0.036 13.7 0.2 0.057 13.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Mitofilin PF09731.4 ETO33756.1 - 0.00072 18.3 7.5 0.001 17.8 5.2 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein TMF_TATA_bd PF12325.3 ETO33756.1 - 0.0064 16.2 7.0 0.11 12.2 4.9 2.3 1 1 0 1 1 1 1 TATA element modulatory factor 1 TATA binding IncA PF04156.9 ETO33756.1 - 0.066 12.7 1.2 0.13 11.8 0.8 1.5 1 0 0 1 1 1 0 IncA protein 5_nucleotid PF05761.9 ETO33756.1 - 0.071 11.6 1.1 0.11 11.0 0.8 1.3 1 0 0 1 1 1 0 5' nucleotidase family RDM PF11002.3 ETO33756.1 - 0.11 12.2 0.2 0.31 10.7 0.0 1.8 2 0 0 2 2 2 0 RFPL defining motif (RDM) SAM_1 PF00536.25 ETO33756.1 - 0.11 12.7 0.1 0.27 11.4 0.1 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Syntaxin_2 PF14523.1 ETO33756.1 - 0.12 12.3 7.8 1.8 8.6 5.4 2.3 1 1 0 1 1 1 0 Syntaxin-like protein AflR PF08493.5 ETO33756.1 - 0.32 9.9 9.5 0.52 9.3 6.6 1.3 1 0 0 1 1 1 0 Aflatoxin regulatory protein Phasin PF05597.6 ETO33756.1 - 1.1 9.0 7.1 0.58 9.9 3.3 1.8 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Mnd1 PF03962.10 ETO33756.1 - 1.9 8.1 6.8 3.2 7.3 4.7 1.3 1 0 0 1 1 1 0 Mnd1 family Adaptin_binding PF10199.4 ETO33756.1 - 2.3 8.5 8.5 0.54 10.5 3.3 1.9 1 1 1 2 2 2 0 Alpha and gamma adaptin binding protein p34 GrpE PF01025.14 ETO33756.1 - 2.3 7.7 7.8 5.5 6.4 5.4 1.6 1 1 0 1 1 1 0 GrpE CENP-F_leu_zip PF10473.4 ETO33756.1 - 2.9 7.7 11.8 0.84 9.4 6.2 1.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 C2 PF00168.25 ETO33757.1 - 3.3e-22 78.1 0.4 8.8e-22 76.7 0.3 1.8 1 0 0 1 1 1 1 C2 domain Lectin_N PF03954.9 ETO33757.1 - 0.0053 16.1 0.5 0.0053 16.1 0.3 2.1 2 0 0 2 2 2 1 Hepatic lectin, N-terminal domain DivIC PF04977.10 ETO33757.1 - 0.016 14.7 2.4 0.016 14.7 1.7 3.9 1 1 3 4 4 4 0 Septum formation initiator Rhv PF00073.15 ETO33757.1 - 0.064 12.9 3.4 0.08 12.6 1.4 1.8 1 1 0 1 1 1 0 picornavirus capsid protein CALCOCO1 PF07888.6 ETO33757.1 - 0.36 9.0 19.3 0.68 8.1 13.4 1.4 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF724 PF05266.9 ETO33757.1 - 0.44 10.1 8.9 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) IFT20 PF14931.1 ETO33757.1 - 0.57 10.0 17.6 5.7 6.8 0.2 3.2 2 1 0 3 3 3 0 Intraflagellar transport complex B, subunit 20 Cauli_AT PF03233.8 ETO33757.1 - 0.69 9.6 14.7 0.92 9.1 0.2 2.6 2 0 0 2 2 2 0 Aphid transmission protein Reo_sigmaC PF04582.7 ETO33757.1 - 0.71 8.9 6.0 0.47 9.5 1.8 1.8 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Adeno_PIX PF03955.9 ETO33757.1 - 0.79 10.2 6.2 0.24 11.9 0.2 2.3 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Macoilin PF09726.4 ETO33757.1 - 1.1 7.4 18.2 9.8 4.3 12.8 2.0 1 1 0 1 1 1 0 Transmembrane protein ATG16 PF08614.6 ETO33757.1 - 1.2 8.8 25.9 3.1 7.5 1.5 3.0 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) ERM PF00769.14 ETO33757.1 - 2.5 7.5 19.4 0.15 11.5 0.9 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family TMF_TATA_bd PF12325.3 ETO33757.1 - 3.4 7.4 20.6 6.5 6.5 1.2 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF848 PF05852.6 ETO33757.1 - 3.6 7.4 18.9 3 7.6 6.4 2.5 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Pox_A_type_inc PF04508.7 ETO33757.1 - 9.1 6.3 12.4 2.1 8.3 0.9 4.1 3 1 1 4 4 4 0 Viral A-type inclusion protein repeat Tho2 PF11262.3 ETO33757.1 - 9.7 5.1 18.6 2.9 6.8 1.4 2.2 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 WD40 PF00400.27 ETO33758.1 - 9e-29 98.2 15.2 5.5e-10 38.7 2.5 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO33758.1 - 2.5e-09 35.8 3.6 0.0065 14.6 0.1 3.3 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Kelch_1 PF01344.20 ETO33759.1 - 2.7e-05 23.6 2.3 0.0009 18.7 0.2 3.2 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO33759.1 - 0.0001 21.9 2.7 0.2 11.4 0.1 4.6 5 1 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO33759.1 - 0.00053 19.7 0.6 0.08 12.7 0.0 3.1 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO33759.1 - 0.0052 16.7 0.1 0.19 11.7 0.1 2.8 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETO33759.1 - 0.018 15.2 0.1 2.8 8.2 0.1 3.5 3 1 1 4 4 4 0 Kelch motif TLD PF07534.11 ETO33759.1 - 0.034 14.1 1.5 0.069 13.1 0.1 2.1 1 1 1 2 2 2 0 TLD FDX-ACB PF03147.9 ETO33760.1 - 1.4e-22 79.6 0.3 1.9e-22 79.2 0.2 1.2 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2d PF01409.15 ETO33760.1 - 1.1e-12 47.7 0.0 2.2e-12 46.7 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) Sulfotransfer_2 PF03567.9 ETO33761.1 - 0.0017 18.0 2.7 0.002 17.8 1.9 1.0 1 0 0 1 1 1 1 Sulfotransferase family Mad3_BUB1_II PF08171.6 ETO33761.1 - 0.034 14.0 1.8 0.034 14.0 1.2 2.1 1 1 1 2 2 2 0 Mad3/BUB1 homology region 2 PFK PF00365.15 ETO33761.1 - 0.1 11.5 1.4 0.12 11.2 1.0 1.0 1 0 0 1 1 1 0 Phosphofructokinase N6_N4_Mtase PF01555.13 ETO33761.1 - 0.13 11.6 9.0 0.14 11.6 6.2 1.1 1 0 0 1 1 1 0 DNA methylase Tropomyosin_1 PF12718.2 ETO33762.1 - 0.0022 17.8 3.3 0.0022 17.8 2.3 2.1 2 0 0 2 2 2 1 Tropomyosin like Mod_r PF07200.8 ETO33762.1 - 0.0056 16.6 1.3 0.0056 16.6 0.9 1.8 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein KLRAQ PF10205.4 ETO33762.1 - 0.0082 16.1 2.0 0.0082 16.1 1.4 1.8 2 0 0 2 2 2 1 Predicted coiled-coil domain-containing protein CCDC155 PF14662.1 ETO33762.1 - 0.013 15.0 9.7 0.026 14.1 3.4 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 DUF496 PF04363.7 ETO33762.1 - 0.015 15.0 0.9 0.015 15.0 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF496) DUF2353 PF09789.4 ETO33762.1 - 0.056 12.6 5.0 0.026 13.8 1.6 1.7 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Microtub_assoc PF07989.6 ETO33762.1 - 0.086 12.6 7.6 0.051 13.4 1.2 2.4 2 0 0 2 2 2 0 Microtubule associated ADIP PF11559.3 ETO33762.1 - 0.09 12.6 5.3 0.04 13.8 1.2 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding EMP24_GP25L PF01105.19 ETO33762.1 - 0.1 12.3 4.6 1.1 8.9 0.1 2.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Tnp_P_element PF12017.3 ETO33762.1 - 0.75 8.9 4.1 0.25 10.5 0.5 1.8 2 0 0 2 2 2 0 Transposase protein TMF_DNA_bd PF12329.3 ETO33762.1 - 1.2 9.0 15.2 2.5 7.9 1.1 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding bZIP_2 PF07716.10 ETO33762.1 - 2.4 8.0 11.3 5.7 6.8 3.9 2.8 2 0 0 2 2 2 0 Basic region leucine zipper Sec2p PF06428.6 ETO33762.1 - 2.8 7.8 7.9 0.28 11.0 1.8 2.0 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p DUF904 PF06005.7 ETO33762.1 - 3.1 8.1 14.3 14 6.0 5.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF904) Lzipper-MIP1 PF14389.1 ETO33762.1 - 3.3 7.8 10.3 0.094 12.8 1.4 2.5 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Jnk-SapK_ap_N PF09744.4 ETO33762.1 - 4.5 7.2 12.2 0.65 9.9 5.3 1.8 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Snapin_Pallidin PF14712.1 ETO33762.1 - 4.5 7.6 8.0 0.72 10.2 1.6 2.1 2 0 0 2 2 2 0 Snapin/Pallidin DivIC PF04977.10 ETO33762.1 - 9 5.8 12.2 9.8 5.7 1.4 3.2 2 1 1 3 3 3 0 Septum formation initiator DUF258 PF03193.11 ETO33764.1 - 2e-05 23.8 0.1 8.9e-05 21.7 0.1 2.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 ETO33764.1 - 0.00046 20.4 0.0 0.00046 20.4 0.0 3.8 2 1 0 2 2 2 1 ABC transporter MMR_HSR1 PF01926.18 ETO33764.1 - 0.00082 19.3 3.3 0.0023 17.8 0.0 3.6 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_29 PF13555.1 ETO33764.1 - 0.012 15.1 0.1 0.039 13.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 ETO33764.1 - 0.024 14.0 0.0 0.075 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain K_channel_TID PF07941.6 ETO33764.1 - 0.28 11.4 0.8 0.65 10.2 0.6 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain DUF3439 PF11921.3 ETO33764.1 - 1.2 8.9 9.4 3.5 7.3 6.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) V-SNARE_C PF12352.3 ETO33765.1 - 1.1e-07 31.7 0.4 1.1e-07 31.7 0.3 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 ETO33765.1 - 0.0018 17.9 0.5 0.0029 17.2 0.1 1.5 1 1 0 1 1 1 1 Sec20 IL7 PF01415.11 ETO33765.1 - 0.044 13.4 0.6 0.053 13.1 0.4 1.2 1 0 0 1 1 1 0 Interleukin 7/9 family HEAT PF02985.17 ETO33766.1 - 1.3e-34 115.1 16.4 0.00012 21.8 0.0 11.5 11 0 0 11 11 11 8 HEAT repeat HEAT_2 PF13646.1 ETO33766.1 - 9.6e-28 96.3 4.7 3.1e-09 36.9 0.1 6.9 2 1 5 8 8 8 5 HEAT repeats HEAT_EZ PF13513.1 ETO33766.1 - 6.9e-10 39.1 8.3 0.00012 22.3 0.0 7.8 6 2 2 8 8 8 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 ETO33766.1 - 9.5e-10 38.7 0.8 0.043 14.2 0.0 6.5 3 1 5 8 8 8 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 ETO33766.1 - 8.6e-07 27.6 12.6 0.018 13.4 0.1 5.0 2 1 1 4 4 4 1 Adaptin N terminal region CLASP_N PF12348.3 ETO33766.1 - 9.2e-07 28.4 6.4 0.27 10.5 0.0 4.9 2 1 2 4 4 4 3 CLASP N terminal Cohesin_HEAT PF12765.2 ETO33766.1 - 0.00023 21.0 0.9 0.31 11.0 0.0 4.1 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 ETO33766.1 - 0.00034 20.5 5.0 0.93 9.3 0.0 4.8 2 2 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 DUF4042 PF13251.1 ETO33766.1 - 0.0014 18.1 0.6 3.7 6.9 0.0 4.0 3 1 1 4 4 4 2 Domain of unknown function (DUF4042) Arm PF00514.18 ETO33766.1 - 0.0019 17.9 0.9 0.73 9.7 0.0 4.3 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat AP_endonuc_2 PF01261.19 ETO33766.1 - 0.057 12.6 0.0 0.82 8.9 0.0 2.1 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel SAGA-Tad1 PF12767.2 ETO33767.1 - 0.0042 16.7 0.6 0.0061 16.2 0.4 1.3 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit SpoIIIAH PF12685.2 ETO33767.1 - 0.32 10.4 3.4 0.66 9.4 2.3 1.7 1 1 0 1 1 1 0 SpoIIIAH-like protein DUF912 PF06024.7 ETO33768.1 - 0.0032 17.5 9.6 0.0039 17.2 6.6 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Tetraspannin PF00335.15 ETO33768.1 - 0.0037 16.5 1.5 0.0043 16.3 1.1 1.1 1 0 0 1 1 1 1 Tetraspanin family Eapp_C PF10238.4 ETO33768.1 - 0.0054 16.6 4.9 0.0067 16.3 3.4 1.2 1 0 0 1 1 1 1 E2F-associated phosphoprotein DUF4064 PF13273.1 ETO33768.1 - 0.0077 16.3 1.3 0.011 15.8 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) Oxidored_q3 PF00499.15 ETO33768.1 - 0.01 15.6 5.4 0.015 15.0 3.7 1.3 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Bap31 PF05529.7 ETO33768.1 - 0.018 14.5 0.6 0.018 14.5 0.4 1.9 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like ATG27 PF09451.5 ETO33768.1 - 0.018 14.2 0.1 0.019 14.2 0.1 1.1 1 0 0 1 1 1 0 Autophagy-related protein 27 Scs3p PF10261.4 ETO33768.1 - 0.023 13.7 0.3 0.028 13.4 0.2 1.0 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM DUF4611 PF15387.1 ETO33768.1 - 0.041 14.0 0.3 0.047 13.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Peptidase_M56 PF05569.6 ETO33768.1 - 0.042 12.8 1.3 0.051 12.5 0.9 1.0 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF1183 PF06682.7 ETO33768.1 - 0.077 12.5 0.3 0.089 12.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) ETRAMP PF09716.5 ETO33768.1 - 0.11 12.4 5.7 0.15 12.0 4.0 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Shisa PF13908.1 ETO33768.1 - 0.12 12.5 0.3 0.15 12.2 0.2 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Plant_vir_prot PF01307.12 ETO33768.1 - 2.7 7.7 8.0 14 5.4 5.4 2.0 1 1 0 1 1 1 0 Plant viral movement protein Secretin_N_2 PF07655.8 ETO33768.1 - 3.4 8.1 15.1 5.3 7.5 10.5 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain ATP-synt_8 PF00895.15 ETO33768.1 - 5.2 7.3 9.4 2 8.7 0.4 2.3 2 0 0 2 2 2 0 ATP synthase protein 8 ELO PF01151.13 ETO33770.1 - 6.2e-17 61.7 9.1 4.2e-16 59.0 6.0 2.4 1 1 1 2 2 2 1 GNS1/SUR4 family DUF4083 PF13314.1 ETO33770.1 - 0.41 10.5 2.3 1.1 9.1 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) DUF2569 PF10754.4 ETO33770.1 - 3.8 7.7 9.7 11 6.2 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) SpoIIID PF12116.3 ETO33771.1 - 0.0053 16.6 0.3 0.28 11.1 0.0 2.8 2 0 0 2 2 2 1 Stage III sporulation protein D DUF1359 PF07097.6 ETO33771.1 - 0.37 10.8 3.5 0.66 10.0 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1359) DUF2551 PF10826.3 ETO33772.1 - 0.043 13.7 0.1 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2551) DUF2684 PF10885.3 ETO33772.1 - 0.047 13.5 0.1 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2684) Reo_sigmaC PF04582.7 ETO33772.1 - 0.057 12.5 0.6 0.091 11.9 0.4 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein PH_11 PF15413.1 ETO33772.1 - 0.16 12.2 4.2 3.6 7.8 0.3 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain Fzo_mitofusin PF04799.8 ETO33772.1 - 0.34 10.2 28.5 1.5 8.1 7.4 2.9 2 1 1 3 3 3 0 fzo-like conserved region GAS PF13851.1 ETO33772.1 - 0.69 9.0 30.4 0.024 13.8 17.1 1.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding IFT46_B_C PF12317.3 ETO33772.1 - 0.76 9.0 6.8 1.2 8.5 4.7 1.4 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal Cut12 PF11500.3 ETO33772.1 - 0.95 9.1 18.0 0.072 12.7 4.1 2.3 1 1 1 2 2 2 0 Spindle pole body formation-associated protein DUF3584 PF12128.3 ETO33772.1 - 1.1 6.5 24.7 2.2 5.4 17.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Tropomyosin_1 PF12718.2 ETO33772.1 - 1.6 8.5 25.5 0.22 11.3 14.1 2.3 2 1 1 3 3 3 0 Tropomyosin like APG6 PF04111.7 ETO33772.1 - 1.7 7.6 22.5 1.9 7.4 14.6 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 HrpB7 PF09486.5 ETO33772.1 - 1.9 8.4 17.5 16 5.3 12.1 2.4 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) IFT57 PF10498.4 ETO33772.1 - 2.1 7.0 23.0 0.79 8.3 6.1 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Laminin_II PF06009.7 ETO33772.1 - 2.6 7.7 14.0 6.6 6.4 8.4 2.1 1 1 1 2 2 2 0 Laminin Domain II ATG16 PF08614.6 ETO33772.1 - 2.8 7.7 25.3 2.4 7.9 7.4 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) ERM PF00769.14 ETO33772.1 - 3.1 7.2 26.7 0.41 10.1 15.6 1.6 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF1664 PF07889.7 ETO33772.1 - 4.9 6.9 19.0 2.1 8.1 2.2 2.4 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) COG2 PF06148.6 ETO33772.1 - 5.8 6.7 13.2 3 7.7 1.1 2.8 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 FlaC_arch PF05377.6 ETO33772.1 - 6.6 6.7 8.2 7.3 6.5 0.6 3.8 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) Spc7 PF08317.6 ETO33772.1 - 8 5.0 22.9 21 3.6 15.1 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF972 PF06156.8 ETO33772.1 - 8.7 6.7 21.7 0.33 11.3 7.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF3700 PF12481.3 ETO33773.1 - 0.035 13.3 1.6 0.046 12.9 1.1 1.1 1 0 0 1 1 1 0 Aluminium induced protein vMSA PF00695.14 ETO33773.1 - 0.11 11.6 0.3 0.15 11.2 0.2 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus DUF1644 PF07800.7 ETO33773.1 - 0.65 9.8 6.0 6.1 6.6 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) Dfp1_Him1_M PF08630.5 ETO33774.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Dfp1/Him1, central region WD40 PF00400.27 ETO33775.1 - 1.4e-61 202.2 23.5 1.4e-10 40.6 0.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO33775.1 - 3.2e-11 42.0 3.0 0.0097 14.0 0.1 4.3 2 1 3 5 5 5 5 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO33775.1 - 0.033 14.3 13.0 1.7 8.9 0.2 5.4 5 2 0 5 5 5 0 Kelch motif AAA_12 PF13087.1 ETO33776.1 - 7.8e-12 44.9 0.3 1.3e-10 40.9 0.0 2.6 1 1 1 2 2 2 1 AAA domain ARPC4 PF05856.7 ETO33776.1 - 0.047 13.0 0.1 0.095 12.0 0.1 1.6 1 0 0 1 1 1 0 ARP2/3 complex 20 kDa subunit (ARPC4) Viral_helicase1 PF01443.13 ETO33776.1 - 0.061 12.8 0.8 0.11 12.0 0.1 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 ETO33776.1 - 0.077 13.1 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Nop14 PF04147.7 ETO33777.1 - 7.3 4.3 51.3 8.9 4.0 35.6 1.1 1 0 0 1 1 1 0 Nop14-like family Menin PF05053.8 ETO33778.1 - 0.0046 15.2 4.0 0.0049 15.1 2.8 1.1 1 0 0 1 1 1 1 Menin Ribosomal_L6e PF01159.14 ETO33778.1 - 1.9 8.7 6.7 14 6.0 4.6 2.2 1 1 0 1 1 1 0 Ribosomal protein L6e ANF_receptor PF01094.23 ETO33779.1 - 0.055 12.2 0.2 0.059 12.1 0.2 1.1 1 0 0 1 1 1 0 Receptor family ligand binding region IFRD PF05004.8 ETO33780.1 - 0.016 14.2 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) Cnd1 PF12717.2 ETO33780.1 - 0.019 14.8 1.1 0.027 14.3 0.1 1.8 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 ETO33780.1 - 0.032 14.5 0.0 1.8 8.8 0.0 2.2 1 1 1 2 2 2 0 HEAT repeats WD40 PF00400.27 ETO33783.1 - 3.3e-20 71.1 0.5 5.1e-10 38.8 0.0 2.7 3 0 0 3 3 3 2 WD domain, G-beta repeat VIT1 PF01988.14 ETO33784.1 - 4.3e-63 212.6 0.3 4.3e-63 212.6 0.2 2.0 2 0 0 2 2 2 1 VIT family BK_channel_a PF03493.13 ETO33785.1 - 0.031 14.2 0.4 0.048 13.6 0.3 1.4 1 0 0 1 1 1 0 Calcium-activated BK potassium channel alpha subunit 2OG-FeII_Oxy_3 PF13640.1 ETO33788.1 - 6.4e-08 33.0 0.0 2.2e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 ETO33788.1 - 3.4e-07 30.4 0.0 1.8e-06 28.1 0.0 2.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 ETO33788.1 - 0.0078 15.8 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Utp11 PF03998.8 ETO33789.1 - 4.5e-13 49.5 6.4 5.4e-13 49.3 4.4 1.0 1 0 0 1 1 1 1 Utp11 protein Rbsn PF11464.3 ETO33789.1 - 0.01 15.3 0.4 0.019 14.4 0.3 1.5 1 0 0 1 1 1 0 Rabenosyn Rab binding domain ApoL PF05461.6 ETO33789.1 - 0.017 14.4 1.7 0.02 14.1 1.2 1.1 1 0 0 1 1 1 0 Apolipoprotein L HTH_19 PF12844.2 ETO33789.1 - 0.05 13.6 2.1 0.095 12.7 1.5 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF1906 PF08924.6 ETO33789.1 - 0.15 11.9 0.2 0.24 11.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1906) PUB PF09409.5 ETO33791.1 - 0.0099 15.6 1.4 0.055 13.2 1.0 2.2 1 1 0 1 1 1 1 PUB domain Tox-HDC PF15656.1 ETO33792.1 - 0.091 12.9 0.1 0.3 11.3 0.0 1.9 1 1 0 1 1 1 0 Toxin with a H, D/N and C signature DUF3450 PF11932.3 ETO33792.1 - 0.095 11.9 8.5 0.12 11.6 5.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) BLOC1_2 PF10046.4 ETO33792.1 - 0.41 10.8 6.5 0.13 12.4 1.6 2.0 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sec2p PF06428.6 ETO33792.1 - 0.46 10.3 9.5 1.3 8.8 6.4 1.9 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p Bap31 PF05529.7 ETO33792.1 - 5.6 6.3 10.0 15 4.9 6.9 1.7 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like SPX PF03105.14 ETO33793.1 - 1.5e-11 44.6 2.2 2.3e-11 43.9 1.5 1.2 1 0 0 1 1 1 1 SPX domain NUC130_3NT PF08158.7 ETO33793.1 - 0.049 13.9 0.1 0.15 12.4 0.1 1.8 1 0 0 1 1 1 0 NUC130/3NT domain WD40 PF00400.27 ETO33794.1 - 3.2e-192 616.4 38.5 3.7e-13 48.7 0.0 16.1 16 0 0 16 16 16 16 WD domain, G-beta repeat PD40 PF07676.7 ETO33794.1 - 1.8e-17 62.5 36.6 1.8 8.3 0.0 14.8 16 0 0 16 16 16 7 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 ETO33794.1 - 7.8e-16 57.9 6.0 0.027 13.5 0.0 8.4 4 3 3 8 8 8 6 Protein of unknown function (DUF1258) Nup160 PF11715.3 ETO33794.1 - 5.2e-15 54.6 31.1 0.07 11.2 0.0 12.2 1 1 11 12 12 12 7 Nucleoporin Nup120/160 Str_synth PF03088.11 ETO33794.1 - 4.7e-13 48.9 1.3 4.2 7.4 0.0 10.8 7 3 4 12 12 12 2 Strictosidine synthase Cytochrom_D1 PF02239.11 ETO33794.1 - 2.2e-10 39.4 9.0 0.04 12.2 0.0 7.0 3 3 4 8 8 8 5 Cytochrome D1 heme domain SGL PF08450.7 ETO33794.1 - 1.3e-09 37.8 3.3 0.024 14.0 0.0 6.4 1 1 5 6 6 6 2 SMP-30/Gluconolaconase/LRE-like region Resistin PF06954.6 ETO33794.1 - 6.7e-06 26.2 5.0 3.5 7.9 0.0 8.1 6 3 4 10 10 10 1 Resistin Gmad1 PF10647.4 ETO33794.1 - 0.0014 18.1 0.0 2.1 7.6 0.0 4.9 4 1 1 5 5 5 1 Lipoprotein LpqB beta-propeller domain Peptidase_C69 PF03577.10 ETO33794.1 - 0.014 14.3 6.3 7.7 5.2 0.0 6.0 7 0 0 7 7 7 0 Peptidase family C69 CsgF PF10614.4 ETO33794.1 - 0.051 13.5 1.0 14 5.6 0.0 4.1 4 1 1 5 5 5 0 Type VIII secretion system (T8SS), CsgF protein NtA PF03146.10 ETO33794.1 - 0.079 12.6 1.0 7.4 6.2 0.0 4.2 2 1 3 6 6 6 0 Agrin NtA domain mRNA_cap_C PF03919.10 ETO33794.1 - 5.4 7.3 11.5 2.1e+02 2.2 0.0 6.9 8 1 1 9 9 9 0 mRNA capping enzyme, C-terminal domain WD40 PF00400.27 ETO33796.1 - 2.6e-44 147.5 7.7 2.7e-10 39.7 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO33796.1 - 1.8e-06 26.4 0.2 0.0063 14.8 0.0 2.4 2 1 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.3 ETO33796.1 - 6.2e-06 24.6 8.5 0.0087 14.2 0.1 4.1 2 2 2 4 4 4 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO33796.1 - 0.00045 19.7 0.2 0.014 14.8 0.1 2.2 1 1 1 2 2 2 2 PQQ-like domain Me-amine-dh_H PF06433.6 ETO33796.1 - 0.0075 14.9 0.0 0.069 11.7 0.0 2.1 2 0 0 2 2 2 1 Methylamine dehydrogenase heavy chain (MADH) Nbas_N PF15492.1 ETO33796.1 - 0.0087 15.1 0.2 2.1 7.3 0.0 3.2 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal BBS2_Mid PF14783.1 ETO33796.1 - 0.012 15.3 2.5 2.7 7.7 0.0 3.8 3 2 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Mid2 PF04478.7 ETO33796.1 - 0.034 13.5 4.0 0.24 10.8 0.2 3.6 2 1 2 4 4 4 0 Mid2 like cell wall stress sensor PD40 PF07676.7 ETO33796.1 - 0.041 13.5 2.4 3.9 7.2 0.0 4.0 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF1652 PF07865.6 ETO33796.1 - 0.1 12.1 0.0 0.37 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1652) zf-C2HC PF01530.13 ETO33796.1 - 0.13 12.0 0.1 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Zinc finger, C2HC type Proteasome_A_N PF10584.4 ETO33796.1 - 0.6 9.4 2.0 11 5.4 0.0 3.3 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Beta_helix PF13229.1 ETO33798.1 - 6.1e-09 35.8 5.3 6.1e-09 35.8 3.7 4.8 4 1 0 4 4 4 2 Right handed beta helix region Chlam_PMP PF02415.12 ETO33798.1 - 3.1 8.2 28.7 0.24 11.7 0.2 8.5 9 0 0 9 9 9 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Pkinase PF00069.20 ETO33799.1 - 7.8e-58 195.6 0.0 1.6e-57 194.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO33799.1 - 9.6e-29 100.2 0.1 3.8e-26 91.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 ETO33799.1 - 0.00022 20.3 0.0 0.0022 17.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like KA1 PF02149.14 ETO33799.1 - 0.00039 19.8 0.1 0.00077 18.8 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 APH PF01636.18 ETO33799.1 - 0.022 14.4 0.1 0.077 12.7 0.1 1.9 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 ETO33799.1 - 0.08 12.5 1.4 0.094 12.2 0.1 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Bud13 PF09736.4 ETO33799.1 - 0.99 9.6 7.9 0.23 11.7 3.1 1.7 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex DUF2201_N PF13203.1 ETO33800.1 - 0.12 11.5 2.8 0.15 11.2 2.0 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain WD40 PF00400.27 ETO33803.1 - 3.9e-43 143.8 10.7 2.6e-11 42.9 0.6 4.5 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO33803.1 - 0.00086 17.5 0.1 0.047 11.8 0.0 2.5 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF851 PF05867.6 ETO33803.1 - 0.06 12.5 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF851) PUB PF09409.5 ETO33804.1 - 0.00081 19.1 5.8 0.062 13.0 3.6 2.4 1 1 0 1 1 1 1 PUB domain CW_binding_1 PF01473.15 ETO33804.1 - 0.26 11.4 5.3 0.91 9.7 3.7 2.0 1 0 0 1 1 1 0 Putative cell wall binding repeat Baculo_p74_N PF08404.5 ETO33805.1 - 0.0057 15.4 0.1 0.0095 14.7 0.1 1.3 1 0 0 1 1 1 1 Baculoviridae P74 N-terminal Daxx PF03344.10 ETO33807.1 - 0.0015 17.1 12.3 0.0015 17.1 8.6 1.9 2 0 0 2 2 2 1 Daxx Family CDC45 PF02724.9 ETO33807.1 - 0.0033 15.5 8.9 0.0042 15.1 6.2 1.2 1 0 0 1 1 1 1 CDC45-like protein PI3K_1B_p101 PF10486.4 ETO33807.1 - 0.037 11.6 0.5 0.048 11.2 0.4 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Ycf1 PF05758.7 ETO33807.1 - 0.48 8.0 6.8 0.57 7.8 4.7 1.1 1 0 0 1 1 1 0 Ycf1 GCIP PF13324.1 ETO33807.1 - 1.4 8.1 8.4 2.6 7.2 5.8 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting SDA1 PF05285.7 ETO33807.1 - 1.5 8.0 21.3 2.5 7.3 14.8 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 ETO33807.1 - 1.6 6.5 22.7 2.5 5.8 15.8 1.2 1 0 0 1 1 1 0 Nop14-like family DUF4407 PF14362.1 ETO33807.1 - 3.7 6.4 5.7 6.5 5.6 4.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RXT2_N PF08595.6 ETO33807.1 - 3.9 7.2 13.3 8.1 6.2 9.2 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal CCDC84 PF14968.1 ETO33807.1 - 4.9 6.5 8.3 0.47 9.8 2.8 1.5 2 0 0 2 2 2 0 Coiled coil protein 84 APG6 PF04111.7 ETO33807.1 - 5.8 5.8 10.6 9.1 5.2 7.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Tim54 PF11711.3 ETO33807.1 - 7.3 5.0 12.6 0.35 9.4 4.7 1.7 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Kelch_6 PF13964.1 ETO33808.1 - 0.00045 20.2 3.1 0.76 10.0 0.0 3.7 3 1 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 ETO33808.1 - 0.085 12.8 7.8 11 6.1 0.0 4.1 5 0 0 5 5 5 0 Kelch motif DLD PF14878.1 ETO33809.1 - 0.017 15.2 1.5 0.97 9.5 0.1 2.3 2 0 0 2 2 2 0 Death-like domain of SPT6 Nucleoporin_N PF08801.6 ETO33810.1 - 4e-26 91.7 0.1 4.5e-24 84.9 0.1 2.0 1 1 0 1 1 1 1 Nup133 N terminal like Ubiquitin_3 PF14836.1 ETO33810.1 - 0.054 13.1 0.1 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-like domain PQQ_3 PF13570.1 ETO33810.1 - 0.12 12.6 0.0 0.44 10.8 0.0 2.0 1 0 0 1 1 1 0 PQQ-like domain Tubulin PF00091.20 ETO33811.1 - 1.1e-64 218.2 0.1 1.9e-64 217.4 0.1 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO33811.1 - 3.3e-35 120.8 0.0 5.2e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Ribosomal_L13 PF00572.13 ETO33812.1 - 1.2e-35 122.3 0.0 2.5e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 CLASP_N PF12348.3 ETO33814.1 - 0.0025 17.1 0.1 0.0038 16.6 0.1 1.2 1 0 0 1 1 1 1 CLASP N terminal DUF1510 PF07423.6 ETO33815.1 - 2.7e-05 23.6 7.5 4.5e-05 22.9 5.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1510) Ycf1 PF05758.7 ETO33815.1 - 0.0081 13.9 0.3 0.0091 13.7 0.2 1.0 1 0 0 1 1 1 1 Ycf1 Nucleoside_tran PF01733.13 ETO33815.1 - 0.017 14.2 0.1 0.028 13.6 0.1 1.5 1 1 0 1 1 1 0 Nucleoside transporter TRAP_alpha PF03896.11 ETO33815.1 - 0.022 13.7 0.1 0.022 13.7 0.1 2.0 1 1 1 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit SID-1_RNA_chan PF13965.1 ETO33815.1 - 0.028 12.6 0.2 0.041 12.0 0.1 1.4 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 SpoIIIAH PF12685.2 ETO33815.1 - 0.038 13.4 7.0 0.11 11.9 4.9 1.6 1 1 0 1 1 1 0 SpoIIIAH-like protein Ctr PF04145.10 ETO33815.1 - 0.13 12.2 0.1 0.23 11.4 0.0 1.6 1 1 0 1 1 1 0 Ctr copper transporter family OAD_gamma PF04277.8 ETO33815.1 - 0.15 12.4 2.3 0.8 10.1 0.0 2.2 1 1 1 2 2 2 0 Oxaloacetate decarboxylase, gamma chain FAM176 PF14851.1 ETO33815.1 - 0.76 9.4 9.5 0.26 10.9 0.2 2.1 1 1 1 2 2 2 0 FAM176 family WD40 PF00400.27 ETO33816.1 - 1.3e-27 94.6 13.6 2.9e-07 30.1 0.1 6.6 5 1 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO33816.1 - 0.041 12.0 0.1 3.5 5.6 0.0 2.4 1 1 0 2 2 2 0 Nucleoporin Nup120/160 DWNN PF08783.6 ETO33816.1 - 0.083 12.8 0.3 0.16 11.9 0.2 1.5 1 0 0 1 1 1 0 DWNN domain Conotoxin PF02950.12 ETO33817.1 - 1.1 10.0 4.2 11 6.8 0.1 2.5 2 0 0 2 2 2 0 Conotoxin OATP PF03137.15 ETO33817.1 - 2.2 6.2 6.7 0.51 8.3 1.2 1.9 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_S49_N PF08496.5 ETO33817.1 - 2.8 7.7 10.6 5.1 6.8 3.5 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal OAD_gamma PF04277.8 ETO33817.1 - 3.4 8.1 7.8 2.4 8.6 0.1 2.4 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Josephin PF02099.12 ETO33818.1 - 2.3e-07 30.5 0.1 1.3e-06 28.0 0.0 2.3 2 0 0 2 2 2 1 Josephin DUF4512 PF14975.1 ETO33818.1 - 0.017 15.8 3.8 0.031 15.1 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4512) Spore_GerAC PF05504.6 ETO33819.1 - 0.17 11.6 3.2 2.2 8.0 0.4 2.2 2 0 0 2 2 2 0 Spore germination B3/ GerAC like, C-terminal TPR_11 PF13414.1 ETO33823.1 - 5.5e-20 70.7 2.8 6.2e-12 44.9 0.1 2.4 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 ETO33823.1 - 1e-11 43.8 1.8 0.0029 17.4 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO33823.1 - 5.1e-11 41.6 7.3 1e-05 24.8 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO33823.1 - 2.3e-06 27.3 0.5 0.031 14.4 0.0 3.5 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO33823.1 - 0.00071 19.1 0.6 0.31 10.9 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO33823.1 - 0.00076 19.3 1.1 15 5.5 0.0 3.9 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat DUF3808 PF10300.4 ETO33823.1 - 0.018 13.6 0.4 0.022 13.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) TPR_19 PF14559.1 ETO33823.1 - 0.059 13.7 0.0 2.9 8.3 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 ETO33823.1 - 0.078 13.1 1.5 0.13 12.3 1.0 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 ETO33823.1 - 0.091 13.4 0.0 3.9 8.2 0.0 2.4 3 1 0 3 3 3 0 Tetratricopeptide repeat CAP_GLY PF01302.20 ETO33824.1 - 3.4e-133 433.5 50.1 5.3e-17 61.2 0.4 12.3 12 0 0 12 12 12 12 CAP-Gly domain Hint_2 PF13403.1 ETO33824.1 - 0.00016 21.6 3.4 15 5.5 0.0 7.2 8 0 0 8 8 8 1 Hint domain YajC PF02699.10 ETO33824.1 - 0.0024 17.5 33.4 1.4 8.6 0.1 11.0 12 0 0 12 12 12 2 Preprotein translocase subunit TraH_2 PF06871.6 ETO33824.1 - 0.093 12.1 1.4 0.45 9.9 0.0 2.8 2 0 0 2 2 2 0 TraH_2 DUF2196 PF09962.4 ETO33824.1 - 1.4 8.7 10.8 11 5.8 0.1 5.1 5 0 0 5 5 5 0 Uncharacterized conserved protein (DUF2196) MS_channel PF00924.13 ETO33824.1 - 3 7.1 7.0 5.4 6.2 0.1 3.7 4 0 0 4 4 4 0 Mechanosensitive ion channel WD40 PF00400.27 ETO33825.1 - 2e-69 227.2 23.8 1.4e-12 46.9 0.0 7.1 6 1 1 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO33825.1 - 1.7e-09 36.4 8.2 0.015 13.4 0.0 4.6 1 1 4 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO33825.1 - 6.1e-09 35.8 1.5 0.0022 17.7 0.0 3.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 ETO33825.1 - 4.1e-05 22.5 0.9 7.7e-05 21.6 0.6 1.4 1 1 0 1 1 1 1 Coatomer WD associated region Cytochrom_D1 PF02239.11 ETO33825.1 - 7.2e-05 21.2 0.8 0.01 14.1 0.0 2.8 2 1 1 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO33825.1 - 0.0002 20.2 9.6 0.086 11.5 0.6 4.1 1 1 1 3 3 3 2 Nup133 N terminal like PQQ_2 PF13360.1 ETO33825.1 - 0.00071 19.0 0.4 0.0058 16.1 0.2 2.5 1 1 1 2 2 2 1 PQQ-like domain DUF1258 PF06869.7 ETO33825.1 - 0.0023 17.0 0.7 2 7.4 0.0 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF1258) PD40 PF07676.7 ETO33825.1 - 0.018 14.6 10.6 10 5.9 0.1 5.3 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Str_synth PF03088.11 ETO33825.1 - 0.03 14.3 0.9 6.7 6.8 0.0 3.8 4 1 1 5 5 5 0 Strictosidine synthase Proteasome_A_N PF10584.4 ETO33825.1 - 0.09 12.1 7.7 9.4 5.6 0.0 4.6 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Kelch_4 PF13418.1 ETO33826.1 - 1.6e-06 27.7 5.7 4.5e-05 23.1 0.4 2.5 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO33826.1 - 4.7e-05 23.3 7.7 0.00012 22.0 0.2 3.1 3 1 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 ETO33826.1 - 0.00078 19.5 0.9 0.0055 16.8 0.1 2.2 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO33826.1 - 0.023 14.6 6.8 0.057 13.3 0.6 2.7 3 0 0 3 3 3 0 Kelch motif Kelch_1 PF01344.20 ETO33826.1 - 0.026 14.0 7.3 0.13 11.8 0.6 3.3 3 1 0 3 3 3 0 Kelch motif Spt5_N PF11942.3 ETO33827.1 - 0.058 14.0 11.7 0.087 13.4 8.1 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF572 PF04502.8 ETO33827.1 - 0.53 9.4 14.1 0.68 9.0 9.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) BIR PF00653.16 ETO33829.1 - 0.033 14.6 0.1 20 5.6 0.0 3.2 3 0 0 3 3 3 0 Inhibitor of Apoptosis domain UPF0075 PF03702.9 ETO33830.1 - 0.028 13.3 0.0 0.041 12.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0075) Abhydrolase_6 PF12697.2 ETO33831.1 - 1.1e-15 58.0 0.0 4e-15 56.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETO33831.1 - 9.3e-14 51.3 0.0 5.3e-13 48.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETO33831.1 - 3.4e-13 49.2 0.5 8.6e-13 47.9 0.3 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 ETO33831.1 - 5.7e-07 29.3 1.9 0.012 15.2 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETO33831.1 - 0.0011 18.2 0.4 0.022 13.9 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 ETO33831.1 - 0.004 16.6 0.0 2.4 7.5 0.0 2.2 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.8 ETO33831.1 - 0.0081 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 ETO33831.1 - 0.05 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase zf-MYND PF01753.13 ETO33832.1 - 2.7e-10 39.9 21.2 4.7e-10 39.1 14.7 1.4 1 0 0 1 1 1 1 MYND finger DUF3642 PF12182.3 ETO33832.1 - 0.13 12.7 1.1 1.6 9.2 0.1 2.2 2 0 0 2 2 2 0 Bacterial lipoprotein zf-HIT PF04438.11 ETO33832.1 - 4.5 7.0 17.1 0.77 9.4 9.3 1.7 2 0 0 2 2 2 0 HIT zinc finger SWI-SNF_Ssr4 PF08549.5 ETO33835.1 - 0.12 10.6 0.3 0.16 10.2 0.2 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Vma12 PF11712.3 ETO33835.1 - 2.1 8.0 7.2 5.4 6.7 5.0 1.9 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3439 PF11921.3 ETO33836.1 - 0.00052 19.7 7.0 0.0011 18.7 4.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) SSP160 PF06933.6 ETO33836.1 - 0.01 13.8 9.3 0.013 13.4 6.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TPR_19 PF14559.1 ETO33836.1 - 0.014 15.6 0.1 0.79 10.0 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 ETO33836.1 - 0.017 14.7 0.2 4.6 6.9 0.0 2.7 1 1 1 3 3 3 0 TPR repeat PCI PF01399.22 ETO33836.1 - 0.019 15.3 0.8 0.062 13.6 0.0 2.2 2 1 0 2 2 2 0 PCI domain ATP13 PF12921.2 ETO33836.1 - 0.022 14.1 0.1 0.056 12.8 0.1 1.7 1 0 0 1 1 1 0 Mitochondrial ATPase expression TPR_2 PF07719.12 ETO33836.1 - 0.034 14.0 0.4 0.49 10.4 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 ETO33836.1 - 0.064 13.4 0.1 2.5 8.3 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Sporozoite_P67 PF05642.6 ETO33836.1 - 0.45 8.3 6.9 0.65 7.7 4.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4512 PF14975.1 ETO33836.1 - 0.77 10.6 4.7 2.3 9.1 3.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) NST1 PF13945.1 ETO33836.1 - 1.2 9.1 7.2 2.2 8.3 5.0 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator TRM PF02005.11 ETO33837.1 - 8.2e-19 67.7 0.2 2e-17 63.1 0.1 2.1 2 0 0 2 2 2 1 N2,N2-dimethylguanosine tRNA methyltransferase NARP1 PF12569.3 ETO33837.1 - 0.00018 20.4 2.9 0.00021 20.1 2.0 1.1 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 DUF2011 PF09428.5 ETO33837.1 - 0.0017 18.2 7.6 0.0025 17.6 5.3 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) BLVR PF06375.6 ETO33837.1 - 0.011 15.5 9.2 0.016 15.0 6.4 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) TRAP_alpha PF03896.11 ETO33837.1 - 0.018 14.0 0.1 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Hom_end_hint PF05203.11 ETO33837.1 - 0.038 13.7 0.2 0.039 13.6 0.1 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint Peptidase_S49_N PF08496.5 ETO33837.1 - 0.083 12.6 4.1 0.13 12.0 2.8 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PBP1_TM PF14812.1 ETO33837.1 - 0.096 13.0 11.7 0.16 12.3 8.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SspB PF04386.8 ETO33837.1 - 0.11 12.0 2.9 0.17 11.4 2.0 1.2 1 0 0 1 1 1 0 Stringent starvation protein B CDC45 PF02724.9 ETO33837.1 - 0.12 10.3 3.7 0.14 10.1 2.5 1.1 1 0 0 1 1 1 0 CDC45-like protein FLO_LFY PF01698.11 ETO33837.1 - 0.2 10.4 8.3 0.27 10.0 5.7 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein SR-25 PF10500.4 ETO33837.1 - 0.54 9.6 15.7 0.88 8.9 10.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FAM176 PF14851.1 ETO33837.1 - 0.71 9.5 6.7 1.2 8.8 4.7 1.3 1 0 0 1 1 1 0 FAM176 family Nucleo_P87 PF07267.6 ETO33837.1 - 0.87 8.1 6.8 1.1 7.9 4.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Paramyxo_ncap PF00973.14 ETO33837.1 - 1.8 7.1 3.8 2.4 6.7 2.6 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Sec62 PF03839.11 ETO33837.1 - 1.9 7.8 10.0 2.7 7.3 6.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DDRGK PF09756.4 ETO33837.1 - 2.9 7.2 20.5 4.3 6.7 14.2 1.1 1 0 0 1 1 1 0 DDRGK domain Pox_Ag35 PF03286.9 ETO33837.1 - 3.4 7.1 14.4 4.8 6.6 10.0 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Med19 PF10278.4 ETO33837.1 - 8 6.1 16.4 11 5.6 11.4 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF3451 PF11933.3 ETO33837.1 - 9.6 5.9 14.0 15 5.2 9.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3451) DUF1510 PF07423.6 ETO33838.1 - 0.28 10.5 20.1 0.31 10.3 13.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ycf1 PF05758.7 ETO33838.1 - 0.93 7.1 8.4 0.93 7.1 5.8 1.0 1 0 0 1 1 1 0 Ycf1 YqfQ PF14181.1 ETO33838.1 - 2.5 8.1 14.5 3 7.8 10.0 1.1 1 0 0 1 1 1 0 YqfQ-like protein Pox_Ag35 PF03286.9 ETO33838.1 - 5.1 6.5 20.3 5.7 6.4 14.1 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Vfa1 PF08432.5 ETO33838.1 - 5.4 6.9 25.4 7 6.6 17.6 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NPR3 PF03666.8 ETO33838.1 - 7.3 5.0 15.8 8.1 4.8 11.0 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Cons_hypoth698 PF03601.9 ETO33839.1 - 0.012 14.3 0.0 0.019 13.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 698 Kelch_6 PF13964.1 ETO33840.1 - 3.1e-10 39.7 1.5 0.0038 17.3 0.1 4.3 3 1 1 4 4 4 3 Kelch motif Kelch_1 PF01344.20 ETO33840.1 - 3.3e-10 39.3 1.7 0.00088 18.7 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO33840.1 - 1.9e-08 33.7 0.2 0.0071 16.0 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO33840.1 - 9.5e-07 28.4 0.4 0.0023 17.6 0.0 3.6 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO33840.1 - 1.9e-06 27.7 4.0 0.99 9.4 0.1 4.7 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 ETO33840.1 - 0.028 14.5 0.1 20 5.4 0.0 4.2 4 0 0 4 4 4 0 Galactose oxidase, central domain Hexapep_2 PF14602.1 ETO33840.1 - 0.15 11.6 0.9 0.38 10.3 0.6 1.7 1 0 0 1 1 1 0 Hexapeptide repeat of succinyl-transferase Ctr PF04145.10 ETO33841.1 - 0.2 11.6 1.7 0.53 10.3 1.2 1.7 1 0 0 1 1 1 0 Ctr copper transporter family DUF4175 PF13779.1 ETO33841.1 - 0.22 9.1 4.8 0.33 8.6 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Band_3_cyto PF07565.8 ETO33841.1 - 0.55 9.7 5.3 0.96 8.9 3.7 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Tim54 PF11711.3 ETO33841.1 - 2 6.9 7.0 0.43 9.1 1.0 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 LMBR1 PF04791.11 ETO33841.1 - 2.4 6.6 4.4 2.9 6.3 3.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2370 PF10176.4 ETO33841.1 - 2.6 7.3 7.7 6.3 6.0 5.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Pex14_N PF04695.8 ETO33841.1 - 4.5 7.3 10.3 0.54 10.2 4.1 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hydrolase_like PF13242.1 ETO33842.1 - 0.00012 21.6 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like MMR_HSR1_C PF08438.5 ETO33842.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.5 1 1 1 2 2 2 0 GTPase of unknown function C-terminal BSMAP PF12280.3 ETO33843.1 - 1.8 8.4 9.8 0.07 13.0 2.0 1.9 1 1 1 2 2 2 0 Brain specific membrane anchored protein Rhomboid PF01694.17 ETO33845.1 - 0.13 12.2 12.4 0.14 12.1 2.6 2.4 1 1 1 2 2 2 0 Rhomboid family Reticulon PF02453.12 ETO33845.1 - 0.13 11.8 1.0 0.21 11.2 0.3 1.6 1 1 0 1 1 1 0 Reticulon DUF2975 PF11188.3 ETO33845.1 - 0.44 10.2 3.6 0.75 9.5 2.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) DUF1228 PF06779.9 ETO33845.1 - 4.9 7.2 7.1 1.2 9.2 0.5 2.8 3 1 0 4 4 4 0 Protein of unknown function (DUF1228) BBP1_N PF15271.1 ETO33846.1 - 0.07 13.4 1.6 0.7 10.2 0.0 2.9 3 0 0 3 3 3 0 Spindle pole body component BBP1, Mps2-binding protein RHD3 PF05879.7 ETO33847.1 - 0.0005 18.1 0.1 0.00078 17.4 0.1 1.3 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) TetR_C_5 PF08360.6 ETO33847.1 - 0.0097 15.8 0.1 0.026 14.4 0.0 1.8 1 0 0 1 1 1 1 QacR-like protein, C-terminal region WD40 PF00400.27 ETO33848.1 - 4e-57 188.1 17.1 1.1e-11 44.1 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat PQQ_2 PF13360.1 ETO33848.1 - 9.3e-06 25.2 0.2 0.0021 17.5 0.0 2.8 2 1 0 2 2 2 2 PQQ-like domain Cytochrom_D1 PF02239.11 ETO33848.1 - 8.5e-05 21.0 0.7 0.0074 14.6 0.0 2.6 1 1 0 2 2 2 2 Cytochrome D1 heme domain Hira PF07569.6 ETO33848.1 - 0.00037 19.7 0.8 11 5.1 0.0 5.3 3 1 3 6 6 6 1 TUP1-like enhancer of split Proteasome_A_N PF10584.4 ETO33848.1 - 0.012 14.9 0.5 11 5.4 0.0 3.8 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 ETO33849.1 - 2.6e-67 220.4 9.1 1.5e-12 46.8 0.3 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO33849.1 - 1.9e-11 44.0 0.4 4.2e-06 26.5 0.0 4.0 2 1 3 5 5 5 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO33849.1 - 1.1e-07 30.3 3.5 0.0085 14.2 0.1 4.4 1 1 2 4 4 4 3 Nucleoporin Nup120/160 PD40 PF07676.7 ETO33849.1 - 2.4e-06 27.0 3.2 0.98 9.1 0.0 5.1 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO33849.1 - 7.6e-06 24.4 0.5 0.016 13.4 0.0 3.2 2 1 1 3 3 3 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO33849.1 - 2.7e-05 23.7 0.1 0.52 9.7 0.0 3.0 1 1 1 3 3 3 2 PQQ-like domain Nucleoporin_N PF08801.6 ETO33849.1 - 0.0049 15.6 10.5 0.59 8.8 0.1 3.8 1 1 0 3 3 3 2 Nup133 N terminal like Abp2 PF09441.5 ETO33849.1 - 0.054 13.4 0.7 11 5.9 0.1 2.4 2 0 0 2 2 2 0 ARS binding protein 2 Proteasome_A_N PF10584.4 ETO33849.1 - 4.3 6.7 6.8 33 3.9 0.3 3.8 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature DUF3353 PF11833.3 ETO33850.1 - 2.8 7.3 4.4 2.7 7.4 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) Porph_ging PF09697.5 ETO33850.1 - 3 8.0 9.2 4.2 7.5 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (Porph_ging) Y_phosphatase PF00102.22 ETO33850.1 - 7 5.9 9.4 7.7 5.7 6.5 1.0 1 0 0 1 1 1 0 Protein-tyrosine phosphatase MVL PF12151.3 ETO33852.1 - 0.2 11.3 6.0 0.18 11.4 1.1 2.2 2 0 0 2 2 2 0 Mannan-binding protein DDRGK PF09756.4 ETO33853.1 - 1.4 8.2 18.3 2 7.7 12.7 1.2 1 0 0 1 1 1 0 DDRGK domain Neur_chan_memb PF02932.11 ETO33853.1 - 2.4 7.9 7.4 2.9 7.6 5.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RAMP4 PF06624.7 ETO33853.1 - 6.2 6.4 6.2 48 3.6 0.0 2.5 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 N6-adenineMlase PF10237.4 ETO33854.1 - 5.7e-23 81.3 3.9 8.4e-23 80.8 2.7 1.2 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase SAM_decarbox PF01536.11 ETO33854.1 - 0.015 13.9 2.2 0.023 13.3 1.5 1.2 1 0 0 1 1 1 0 Adenosylmethionine decarboxylase AAA PF00004.24 ETO33855.1 - 1e-06 28.9 0.1 2.2e-06 27.9 0.0 1.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 ETO33856.1 - 6.5e-15 55.5 0.0 1.2e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 ETO33856.1 - 1.9e-06 28.6 0.1 4.9e-06 27.3 0.0 1.8 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.1 ETO33856.1 - 4.5e-06 26.9 0.0 2.2e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETO33856.1 - 5.6e-06 26.5 0.0 1.3e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETO33856.1 - 6.2e-06 26.3 0.0 1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 ETO33856.1 - 6.8e-05 22.5 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 ETO33856.1 - 0.00011 22.0 0.0 0.00022 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 ETO33856.1 - 0.00022 20.8 0.0 0.00084 18.9 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 ETO33856.1 - 0.00028 21.0 0.0 0.00064 19.8 0.0 1.7 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.7 ETO33856.1 - 0.00059 19.5 0.4 0.0017 18.0 0.1 2.1 2 1 1 3 3 2 1 NACHT domain IstB_IS21 PF01695.12 ETO33856.1 - 0.00062 19.2 0.0 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 ETO33856.1 - 0.00066 19.6 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 ETO33856.1 - 0.00093 18.6 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 ETO33856.1 - 0.0014 18.2 0.0 0.037 13.6 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 ETO33856.1 - 0.002 17.7 0.0 0.0038 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 ETO33856.1 - 0.0022 17.0 0.0 0.0038 16.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 ETO33856.1 - 0.0023 17.5 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 ETO33856.1 - 0.0031 17.2 0.0 0.0068 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 ETO33856.1 - 0.0038 16.1 0.0 0.0077 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.8 ETO33856.1 - 0.0043 15.8 0.0 0.0067 15.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Zeta_toxin PF06414.7 ETO33856.1 - 0.0052 15.9 0.0 0.013 14.6 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.1 ETO33856.1 - 0.0081 15.7 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 ETO33856.1 - 0.01 14.8 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 ETO33856.1 - 0.017 15.0 0.0 0.038 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 ETO33856.1 - 0.02 14.1 0.0 0.04 13.1 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein MMR_HSR1 PF01926.18 ETO33856.1 - 0.026 14.4 0.1 0.47 10.4 0.0 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.22 ETO33856.1 - 0.027 14.7 0.0 0.054 13.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.16 ETO33856.1 - 0.031 13.4 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.17 ETO33856.1 - 0.037 12.9 0.0 0.081 11.7 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain KAP_NTPase PF07693.9 ETO33856.1 - 0.038 12.9 0.1 0.21 10.5 0.0 1.9 1 1 0 1 1 1 0 KAP family P-loop domain PduV-EutP PF10662.4 ETO33856.1 - 0.042 13.3 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 ETO33856.1 - 0.044 14.1 1.6 0.2 11.9 0.0 2.3 2 1 0 3 3 2 0 AAA domain MobB PF03205.9 ETO33856.1 - 0.073 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 ETO33856.1 - 0.077 13.4 0.1 1.1 9.7 0.0 2.5 3 0 0 3 3 2 0 Miro-like protein CPT PF07931.7 ETO33856.1 - 0.091 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF258 PF03193.11 ETO33856.1 - 0.092 11.9 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Sigma54_activat PF00158.21 ETO33856.1 - 0.094 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain ADK PF00406.17 ETO33856.1 - 0.11 12.4 0.2 5.7 6.8 0.0 2.3 2 0 0 2 2 2 0 Adenylate kinase Viral_helicase1 PF01443.13 ETO33856.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase FKBP_N PF01346.13 ETO33857.1 - 4.8e-07 29.8 0.0 7.2e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Tom37_C PF11801.3 ETO33858.1 - 0.047 13.5 2.4 0.089 12.6 1.7 1.4 1 0 0 1 1 1 0 Tom37 C-terminal domain Membralin PF09746.4 ETO33858.1 - 0.2 10.6 1.9 0.28 10.1 0.8 1.5 1 1 1 2 2 2 0 Tumour-associated protein CDC45 PF02724.9 ETO33858.1 - 0.31 9.0 7.4 0.43 8.5 5.1 1.2 1 0 0 1 1 1 0 CDC45-like protein HAND PF09110.6 ETO33858.1 - 0.68 10.3 11.3 1.6 9.1 7.8 1.6 1 0 0 1 1 1 0 HAND Actin PF00022.14 ETO33859.1 - 2.1e-38 131.7 0.0 2.7e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Actin Actin PF00022.14 ETO33860.1 - 6.2e-27 94.0 0.0 1.9e-26 92.4 0.0 1.7 1 1 0 1 1 1 1 Actin DUF3169 PF11368.3 ETO33861.1 - 0.014 14.6 5.5 0.024 13.8 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) EcsB PF05975.7 ETO33861.1 - 0.54 8.6 14.8 0.013 13.9 3.9 2.3 1 1 1 2 2 2 0 Bacterial ABC transporter protein EcsB DUF788 PF05620.6 ETO33861.1 - 2.6 7.8 10.7 0.18 11.6 2.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF788) Sterile PF03015.14 ETO33862.1 - 0.0043 17.2 0.9 0.37 11.0 0.0 2.8 3 0 0 3 3 3 2 Male sterility protein PI3K_C2 PF00792.19 ETO33863.1 - 4e-14 52.5 0.0 8.8e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.13 ETO33863.1 - 2.1e-11 43.6 0.1 5e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain PI3Ka PF00613.15 ETO33864.1 - 5.8e-47 159.2 3.8 7.7e-47 158.8 2.4 1.4 1 1 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 ETO33865.1 - 2.6e-28 99.0 0.1 1e-27 97.1 0.0 1.7 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase WBP-1 PF11669.3 ETO33868.1 - 0.043 13.9 1.2 0.086 12.9 0.8 1.5 1 0 0 1 1 1 0 WW domain-binding protein 1 ABC_membrane PF00664.18 ETO33868.1 - 0.084 12.2 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region Mucin PF01456.12 ETO33868.1 - 0.11 12.2 0.1 0.15 11.8 0.1 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein XPG_I PF00867.13 ETO33869.1 - 2.4e-21 75.5 0.0 1.1e-20 73.4 0.0 2.1 2 1 0 2 2 2 1 XPG I-region XPG_N PF00752.12 ETO33869.1 - 1.7e-20 73.1 0.0 5e-20 71.6 0.0 1.8 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.2 ETO33869.1 - 7.6e-08 32.1 0.0 1.8e-07 30.8 0.0 1.5 1 1 0 1 1 1 1 XPG domain containing MIT PF04212.13 ETO33869.1 - 0.0012 18.7 0.7 0.0031 17.3 0.5 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_2 PF07719.12 ETO33869.1 - 0.0019 17.9 0.0 0.0047 16.7 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO33869.1 - 0.0033 17.0 0.6 0.012 15.3 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO33869.1 - 0.0067 16.8 0.1 0.021 15.2 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO33869.1 - 0.015 15.0 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETO33869.1 - 0.019 14.5 0.0 0.064 12.8 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETO33869.1 - 0.031 14.2 0.1 0.077 12.9 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat HATPase_c_5 PF14501.1 ETO33872.1 - 0.096 12.4 3.4 0.12 12.0 2.3 1.3 1 1 0 1 1 1 0 GHKL domain 2-oxoacid_dh PF00198.18 ETO33872.1 - 0.55 9.4 2.9 0.62 9.2 2.0 1.1 1 0 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Imm5 PF14423.1 ETO33872.1 - 1.2 8.7 4.1 1.4 8.4 2.8 1.1 1 0 0 1 1 1 0 Immunity protein Imm5 YARHG PF13308.1 ETO33873.1 - 0.014 14.9 1.8 0.014 14.9 1.2 1.4 2 0 0 2 2 2 0 YARHG domain Pkinase PF00069.20 ETO33875.1 - 5e-08 32.4 0.2 8.6e-08 31.6 0.2 1.4 1 0 0 1 1 1 1 Protein kinase domain PH PF00169.24 ETO33875.1 - 1.1e-07 32.0 0.1 1.9e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 PH domain Pkinase_Tyr PF07714.12 ETO33875.1 - 8.2e-05 21.7 0.1 0.00012 21.2 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH_11 PF15413.1 ETO33875.1 - 0.014 15.6 0.1 0.036 14.3 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain NACHT PF05729.7 ETO33876.1 - 7.5e-10 38.7 0.0 3.7e-09 36.4 0.0 2.2 3 0 0 3 3 3 1 NACHT domain AAA_18 PF13238.1 ETO33876.1 - 6.2e-06 26.5 0.0 3.7e-05 24.0 0.0 2.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ETO33876.1 - 0.00031 20.8 0.0 0.0012 18.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO33876.1 - 0.0014 19.3 0.1 0.021 15.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain RelA_SpoT PF04607.12 ETO33876.1 - 0.0074 16.2 0.3 0.044 13.7 0.2 2.3 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins ATP_bind_2 PF03668.10 ETO33876.1 - 0.019 14.0 0.0 0.038 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop ATPase protein family RNA_helicase PF00910.17 ETO33876.1 - 0.019 15.1 1.3 0.14 12.3 0.0 3.1 3 1 0 3 3 3 0 RNA helicase ABC_tran PF00005.22 ETO33876.1 - 0.03 14.6 0.1 3.6 7.8 0.0 2.9 2 0 0 2 2 2 0 ABC transporter DAP3 PF10236.4 ETO33876.1 - 1 8.2 8.8 0.79 8.5 0.2 3.8 5 0 0 5 5 5 0 Mitochondrial ribosomal death-associated protein 3 UCH PF00443.24 ETO33877.1 - 8.6e-12 44.7 0.5 8.6e-12 44.7 0.4 2.0 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO33877.1 - 7.8e-05 22.2 0.0 0.13 11.6 0.1 2.8 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF4647 PF15504.1 ETO33879.1 - 0.0065 15.3 10.4 0.01 14.7 7.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4647) Menin PF05053.8 ETO33879.1 - 1.1 7.2 10.4 1.5 6.8 7.2 1.1 1 0 0 1 1 1 0 Menin Sed5p PF11416.3 ETO33880.1 - 0.076 12.4 0.5 0.076 12.4 0.3 2.0 2 0 0 2 2 2 0 Integral membrane protein Sed5p Rhabdo_ncap PF00945.13 ETO33880.1 - 0.1 11.1 2.7 0.12 10.9 1.9 1.0 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein TRAP_alpha PF03896.11 ETO33880.1 - 0.53 9.2 3.0 0.48 9.3 2.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RXT2_N PF08595.6 ETO33880.1 - 4.6 7.0 8.7 6.5 6.5 6.0 1.4 1 1 0 1 1 1 0 RXT2-like, N-terminal RVT_1 PF00078.22 ETO33881.1 - 7.5e-06 25.4 0.4 0.00067 19.0 0.0 2.1 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Pox_H7 PF04787.7 ETO33881.1 - 0.23 11.2 1.4 0.56 9.9 1.0 1.6 1 0 0 1 1 1 0 Late protein H7 NACHT PF05729.7 ETO33882.1 - 1.4e-18 67.1 0.0 5.4e-18 65.1 0.0 2.2 1 0 0 1 1 1 1 NACHT domain HEAT_2 PF13646.1 ETO33882.1 - 1.6e-12 47.5 0.0 0.00016 21.8 0.0 7.4 6 1 3 9 9 9 3 HEAT repeats HEAT PF02985.17 ETO33882.1 - 5.5e-12 44.6 0.0 1.8 8.8 0.0 8.7 9 0 0 9 9 9 2 HEAT repeat Ank_3 PF13606.1 ETO33882.1 - 5.7e-08 32.2 0.1 2e-05 24.3 0.0 4.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 ETO33882.1 - 1.1e-07 31.8 0.1 4.6e-07 29.8 0.1 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO33882.1 - 3e-07 30.7 0.4 2.7e-06 27.7 0.1 2.9 3 0 0 3 3 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO33882.1 - 4e-07 30.2 0.1 2.6e-06 27.6 0.1 2.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO33882.1 - 1.1e-05 24.9 0.0 5e-05 22.9 0.0 2.2 1 0 0 1 1 1 1 Ankyrin repeat HEAT_EZ PF13513.1 ETO33882.1 - 0.00057 20.2 0.0 4.6 7.8 0.0 6.0 7 1 2 9 9 7 2 HEAT-like repeat AAA_22 PF13401.1 ETO33882.1 - 0.037 14.1 5.4 0.11 12.6 0.0 4.6 5 1 0 5 5 4 0 AAA domain AAA_16 PF13191.1 ETO33882.1 - 0.046 13.7 0.0 0.48 10.3 0.0 2.6 1 1 1 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 ETO33882.1 - 0.13 11.9 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain Cullin_binding PF03556.10 ETO33883.1 - 3.2 7.9 9.9 7.5 6.7 6.9 1.7 1 1 0 1 1 1 0 Cullin binding DUF2113 PF09886.4 ETO33884.1 - 0.07 12.2 0.1 0.089 11.9 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2113) DUF1593 PF07632.6 ETO33885.1 - 0.037 13.3 3.6 0.04 13.2 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) Paramyxo_NS_C PF02725.9 ETO33885.1 - 1 8.9 8.5 0.061 12.9 0.7 2.0 1 1 1 2 2 2 0 Non-structural protein C TPR_12 PF13424.1 ETO33887.1 - 5.2e-71 234.5 12.7 8.5e-17 60.8 0.1 6.0 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETO33887.1 - 3e-33 112.7 0.0 9.2e-06 25.4 0.0 8.6 9 0 0 9 9 8 7 Tetratricopeptide repeat TPR_2 PF07719.12 ETO33887.1 - 3.4e-31 104.6 26.1 2.2e-05 24.0 0.0 9.6 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_1 PF00515.23 ETO33887.1 - 6.1e-31 104.7 33.5 3.8e-06 26.2 0.7 9.9 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_11 PF13414.1 ETO33887.1 - 2.6e-29 100.6 29.3 5.7e-08 32.2 0.7 6.6 2 2 4 7 7 7 7 TPR repeat TPR_7 PF13176.1 ETO33887.1 - 2.6e-29 98.6 16.8 0.0011 18.6 0.1 9.4 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETO33887.1 - 4.2e-24 82.4 38.6 4.6e-06 26.0 0.1 9.6 8 1 1 9 9 9 7 Tetratricopeptide repeat TPR_17 PF13431.1 ETO33887.1 - 2.9e-12 45.7 9.6 0.95 9.8 0.1 8.8 8 1 0 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO33887.1 - 1.3e-11 44.0 0.0 0.8 10.5 0.0 8.0 9 1 1 10 10 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO33887.1 - 5.9e-11 42.7 0.1 0.025 15.2 0.1 5.8 4 3 2 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO33887.1 - 8.8e-10 38.3 7.7 0.3 11.6 0.0 6.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO33887.1 - 2.6e-09 37.2 5.7 1.2 9.4 0.0 6.9 5 2 2 7 7 7 2 Tetratricopeptide repeat MIT PF04212.13 ETO33887.1 - 8.2e-06 25.6 23.6 0.77 9.6 0.3 6.5 7 1 0 7 7 6 3 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 ETO33887.1 - 8.8e-06 25.7 20.6 0.079 13.1 0.2 5.7 2 1 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.4 ETO33887.1 - 0.00015 21.7 3.2 0.034 14.0 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_3 PF07720.7 ETO33887.1 - 0.00056 19.6 10.1 0.23 11.2 0.2 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO33887.1 - 0.0085 15.3 12.8 0.17 11.1 0.1 6.7 7 0 0 7 7 7 1 SHNi-TPR Fis1_TPR_C PF14853.1 ETO33887.1 - 0.015 15.1 9.3 1.1 9.2 0.3 5.1 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat RPN7 PF10602.4 ETO33887.1 - 0.019 14.3 16.2 0.99 8.7 0.7 4.4 3 1 1 4 4 4 0 26S proteasome subunit RPN7 PPR_1 PF12854.2 ETO33887.1 - 0.11 11.9 0.2 1.1 8.8 0.0 2.7 2 0 0 2 2 2 0 PPR repeat DUF2225 PF09986.4 ETO33887.1 - 0.24 10.8 14.4 3.2 7.1 1.7 4.2 1 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) PPR PF01535.15 ETO33887.1 - 7.5 6.7 13.4 12 6.1 0.0 6.1 9 0 0 9 9 6 0 PPR repeat Conotoxin PF02950.12 ETO33888.1 - 0.048 14.4 0.5 0.28 12.0 0.0 2.4 3 0 0 3 3 3 0 Conotoxin WBP-1 PF11669.3 ETO33888.1 - 0.057 13.5 0.3 0.14 12.2 0.2 1.7 1 0 0 1 1 1 0 WW domain-binding protein 1 Nucleoside_tran PF01733.13 ETO33888.1 - 0.2 10.7 3.8 0.17 11.0 1.4 1.4 1 1 0 1 1 1 0 Nucleoside transporter WD40 PF00400.27 ETO33890.1 - 1.9e-64 211.3 12.8 5.7e-10 38.6 0.1 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO33890.1 - 5.2e-09 34.7 0.1 0.0027 15.8 0.0 4.1 1 1 4 5 5 5 3 Nucleoporin Nup120/160 DUF1541 PF07563.6 ETO33890.1 - 0.12 12.0 2.4 6.8 6.4 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1541) WD40 PF00400.27 ETO33891.1 - 4.6e-68 222.8 20.1 4.9e-14 51.5 0.1 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO33891.1 - 3.3e-13 49.7 0.6 1e-05 25.3 0.0 2.9 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO33891.1 - 8.8e-09 34.0 4.8 0.071 11.2 0.0 4.2 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO33891.1 - 5.1e-06 25.5 9.9 0.14 10.9 0.0 4.3 1 1 2 3 3 3 3 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO33891.1 - 7.1e-06 24.5 0.5 0.00018 19.9 0.1 2.0 1 1 1 2 2 2 1 Cytochrome D1 heme domain DUF4221 PF13970.1 ETO33891.1 - 6.2e-05 22.4 0.2 0.038 13.2 0.0 3.5 1 1 3 4 4 4 1 Domain of unknown function (DUF4221) PD40 PF07676.7 ETO33891.1 - 0.00012 21.6 1.1 3.9 7.2 0.0 5.0 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO33891.1 - 0.00044 20.4 0.3 1.4 9.2 0.0 3.6 3 1 1 4 4 3 1 Resistin Coatomer_WDAD PF04053.9 ETO33891.1 - 0.00048 19.0 0.2 0.14 10.9 0.1 2.6 1 1 2 3 3 3 2 Coatomer WD associated region RicinB_lectin_2 PF14200.1 ETO33891.1 - 0.0021 18.4 0.3 0.11 12.9 0.0 2.6 2 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like PQQ_2 PF13360.1 ETO33891.1 - 0.0058 16.1 0.2 0.039 13.4 0.1 2.3 1 1 1 2 2 2 2 PQQ-like domain DPPIV_N PF00930.16 ETO33891.1 - 0.0076 14.8 0.0 4.9 5.6 0.0 3.1 1 1 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Hira PF07569.6 ETO33891.1 - 0.0086 15.3 0.0 7.4 5.7 0.0 3.1 2 1 1 3 3 3 1 TUP1-like enhancer of split B3_4 PF03483.12 ETO33891.1 - 0.075 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 B3/4 domain DUF1513 PF07433.6 ETO33891.1 - 0.11 11.3 0.1 5.4 5.8 0.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1513) FHA PF00498.21 ETO33892.1 - 0.0017 18.3 0.0 0.0037 17.3 0.0 1.6 2 0 0 2 2 2 1 FHA domain DUF966 PF06136.8 ETO33892.1 - 0.02 14.3 0.6 0.021 14.2 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Dicty_REP PF05086.7 ETO33892.1 - 0.084 10.6 2.4 0.11 10.2 1.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein BDV_P24 PF06595.6 ETO33892.1 - 0.14 11.9 2.2 0.1 12.3 0.5 1.5 2 0 0 2 2 2 0 Borna disease virus P24 protein YlbD_coat PF14071.1 ETO33892.1 - 0.16 12.0 4.0 0.13 12.3 1.3 1.7 1 1 1 2 2 2 0 Putative coat protein SLX9 PF15341.1 ETO33893.1 - 0.082 13.3 9.0 0.17 12.3 6.3 1.5 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 Peptidase_S49_N PF08496.5 ETO33893.1 - 2.1 8.1 7.0 5 6.8 4.8 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal VWA_2 PF13519.1 ETO33894.1 - 5.3e-06 26.6 0.0 1.1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Helicase_C PF00271.26 ETO33894.1 - 0.0032 17.2 0.1 0.016 15.0 0.0 2.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain Beach PF02138.13 ETO33896.1 - 7.2e-97 324.0 0.4 7.2e-97 324.0 0.3 2.0 2 0 0 2 2 2 1 Beige/BEACH domain FYVE PF01363.16 ETO33896.1 - 1.5e-18 66.4 9.0 1.5e-18 66.4 6.2 1.9 2 0 0 2 2 2 1 FYVE zinc finger WD40 PF00400.27 ETO33896.1 - 8.9e-13 47.5 15.3 1.8e-09 37.0 0.1 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat PH_BEACH PF14844.1 ETO33896.1 - 8.9e-10 38.3 1.2 8.9e-10 38.3 0.9 3.0 2 1 1 3 3 3 1 PH domain associated with Beige/BEACH IBR PF01485.16 ETO33896.1 - 0.0032 17.3 7.4 0.0088 15.8 5.1 1.7 1 0 0 1 1 1 1 IBR domain zf-H2C2_2 PF13465.1 ETO33896.1 - 0.077 13.3 2.9 2 8.8 0.2 3.0 2 0 0 2 2 2 0 Zinc-finger double domain zf-RING_5 PF14634.1 ETO33896.1 - 2 8.2 10.4 4.9 6.9 7.2 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Ribosomal_S27e PF01667.12 ETO33896.1 - 5.9 6.5 9.1 1.1e+02 2.5 5.6 3.1 3 0 0 3 3 3 0 Ribosomal protein S27 Baculo_gp64 PF03273.8 ETO33897.1 - 0.00029 19.1 1.7 0.00054 18.2 1.2 1.4 1 0 0 1 1 1 1 Baculovirus gp64 envelope glycoprotein family DUF2721 PF11026.3 ETO33898.1 - 1.3 8.6 11.7 0.47 10.1 3.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) Far-17a_AIG1 PF04750.9 ETO33899.1 - 1.6e-08 33.9 7.3 2.3e-08 33.4 5.0 1.2 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein TMEM192 PF14802.1 ETO33899.1 - 0.51 9.1 3.1 0.83 8.4 2.2 1.4 1 0 0 1 1 1 0 TMEM192 family Bap31 PF05529.7 ETO33899.1 - 2.5 7.5 7.0 5 6.5 0.1 3.1 3 0 0 3 3 3 0 B-cell receptor-associated protein 31-like SR-25 PF10500.4 ETO33900.1 - 0.00094 18.7 6.8 0.00094 18.7 4.7 3.3 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein Adap_comp_sub PF00928.16 ETO33901.1 - 4.9e-46 156.9 0.0 5.9e-46 156.6 0.0 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family S1FA PF04689.8 ETO33901.1 - 0.018 14.9 0.3 0.035 13.9 0.2 1.4 1 0 0 1 1 1 0 DNA binding protein S1FA DUF1817 PF08847.6 ETO33904.1 - 0.047 13.2 0.0 0.12 11.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1817) Macoilin PF09726.4 ETO33905.1 - 0.0088 14.3 25.3 0.011 14.0 17.5 1.2 1 0 0 1 1 1 1 Transmembrane protein zf-C3HC4_2 PF13923.1 ETO33905.1 - 0.017 15.1 1.9 0.017 15.1 1.3 2.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO33905.1 - 0.069 12.9 5.3 0.16 11.8 3.2 2.0 2 0 0 2 2 2 0 Ring finger domain FAM163 PF15069.1 ETO33905.1 - 0.37 11.3 0.1 0.37 11.3 0.0 2.7 2 1 0 3 3 3 0 FAM163 family WD40 PF00400.27 ETO33906.1 - 9.5e-51 167.9 7.4 6.1e-11 41.7 0.0 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO33906.1 - 6e-06 24.6 3.9 0.65 8.0 0.1 4.0 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Str_synth PF03088.11 ETO33906.1 - 0.00011 22.2 0.2 10 6.2 0.0 4.3 1 1 4 5 5 5 1 Strictosidine synthase Nucleoporin_N PF08801.6 ETO33906.1 - 0.00019 20.3 5.2 1 8.0 0.2 3.9 1 1 1 3 3 3 2 Nup133 N terminal like DUF3601 PF12208.3 ETO33906.1 - 0.00025 20.9 0.0 4 7.4 0.0 4.0 2 1 2 4 4 4 1 Domain of unknown function (DUF3601) SGL PF08450.7 ETO33906.1 - 0.0054 16.1 0.0 0.6 9.4 0.0 3.0 1 1 1 3 3 3 1 SMP-30/Gluconolaconase/LRE-like region PQQ_2 PF13360.1 ETO33906.1 - 0.0082 15.6 0.4 0.7 9.3 0.2 2.5 1 1 0 2 2 2 1 PQQ-like domain PD40 PF07676.7 ETO33906.1 - 0.011 15.3 11.0 2.2 8.0 0.0 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 ETO33906.1 - 0.29 10.4 2.1 33 3.9 0.1 3.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 ETO33907.1 - 2.5e-51 169.8 14.3 1.1e-13 50.5 0.1 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO33907.1 - 3.3e-07 28.8 2.9 0.0047 15.1 0.1 3.7 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO33907.1 - 0.00011 21.0 6.4 0.085 11.5 0.7 3.2 2 1 1 3 3 3 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO33907.1 - 0.011 14.0 0.5 0.25 9.5 0.1 2.2 1 1 0 2 2 2 0 Cytochrome D1 heme domain DUF3732 PF12532.3 ETO33907.1 - 0.017 14.6 0.9 19 4.6 0.0 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF3732) DUF1258 PF06869.7 ETO33907.1 - 0.044 12.8 0.2 0.2 10.7 0.1 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1258) USP7_C2 PF14533.1 ETO33907.1 - 0.054 12.9 0.1 42 3.4 0.0 3.2 2 1 0 3 3 3 0 Ubiquitin-specific protease C-terminal DUF1652 PF07865.6 ETO33907.1 - 0.055 13.0 0.1 29 4.3 0.0 3.8 3 1 0 4 4 4 0 Protein of unknown function (DUF1652) Str_synth PF03088.11 ETO33907.1 - 0.076 13.0 0.0 0.24 11.4 0.0 1.9 2 1 0 2 2 2 0 Strictosidine synthase CsgF PF10614.4 ETO33907.1 - 0.12 12.4 0.4 3.6 7.5 0.0 2.7 3 0 0 3 3 3 0 Type VIII secretion system (T8SS), CsgF protein PD40 PF07676.7 ETO33907.1 - 1.2 8.8 4.9 0.74 9.5 0.2 2.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Sigma70_ner PF04546.8 ETO33908.1 - 0.68 9.5 5.9 0.58 9.7 1.5 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region PBP1_TM PF14812.1 ETO33908.1 - 6.2 7.2 9.3 3.4 8.0 4.7 1.8 1 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TAF4 PF05236.9 ETO33909.1 - 0.12 11.6 3.4 0.22 10.7 2.4 1.8 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family WD40 PF00400.27 ETO33910.1 - 3.8e-68 223.1 14.3 7.8e-12 44.6 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO33910.1 - 1e-11 43.6 7.6 0.019 13.1 0.0 5.0 1 1 4 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO33910.1 - 2.5e-11 43.6 1.5 5.3e-05 23.0 0.0 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO33910.1 - 1.1e-08 33.7 4.1 0.0027 16.0 0.2 3.9 1 1 3 4 4 4 3 Cytochrome D1 heme domain Mid2 PF04478.7 ETO33910.1 - 0.00024 20.5 3.1 3.3 7.1 0.0 4.1 2 2 2 4 4 4 1 Mid2 like cell wall stress sensor PQQ_2 PF13360.1 ETO33910.1 - 0.00025 20.5 0.0 0.003 17.0 0.0 2.5 1 1 1 2 2 2 1 PQQ-like domain Hira PF07569.6 ETO33910.1 - 0.00035 19.8 1.7 0.82 8.8 0.1 4.4 1 1 3 5 5 5 1 TUP1-like enhancer of split Coatomer_WDAD PF04053.9 ETO33910.1 - 0.00047 19.0 5.9 0.023 13.5 1.1 3.0 1 1 2 3 3 3 3 Coatomer WD associated region PD40 PF07676.7 ETO33910.1 - 0.0013 18.3 9.3 0.33 10.6 0.1 4.8 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Str_synth PF03088.11 ETO33910.1 - 0.0016 18.4 1.3 8.8 6.4 0.0 4.3 3 3 1 4 4 4 0 Strictosidine synthase Nucleoporin_N PF08801.6 ETO33910.1 - 0.0022 16.8 11.9 0.92 8.1 0.2 5.0 1 1 2 3 3 3 2 Nup133 N terminal like Nbas_N PF15492.1 ETO33910.1 - 0.0026 16.8 0.9 0.71 8.9 0.0 3.0 1 1 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal Ricin_B_lectin PF00652.17 ETO33910.1 - 0.0049 16.8 0.6 0.52 10.3 0.0 2.9 2 1 1 3 3 3 1 Ricin-type beta-trefoil lectin domain Resistin PF06954.6 ETO33910.1 - 0.012 15.8 0.7 1.9 8.7 0.0 3.9 3 1 1 5 5 5 0 Resistin DPPIV_N PF00930.16 ETO33910.1 - 0.044 12.3 1.1 9.4 4.7 0.0 3.1 1 1 1 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region USP7_C2 PF14533.1 ETO33910.1 - 0.092 12.1 1.5 51 3.2 0.1 4.0 1 1 3 5 5 5 0 Ubiquitin-specific protease C-terminal RabGAP-TBC PF00566.13 ETO33910.1 - 0.098 12.1 0.6 65 2.8 0.0 3.9 5 0 0 5 5 5 0 Rab-GTPase-TBC domain Tox-PL PF15644.1 ETO33910.1 - 0.13 13.0 0.1 29 5.4 0.0 3.5 4 0 0 4 4 3 0 Papain fold toxin 1 WD40 PF00400.27 ETO33912.1 - 1.8e-70 230.4 15.8 3.9e-12 45.5 0.0 7.1 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO33912.1 - 8.9e-07 27.4 6.5 0.29 9.2 0.0 5.0 1 1 4 5 5 5 4 Nucleoporin Nup120/160 Kelch_1 PF01344.20 ETO33912.1 - 0.0011 18.4 0.1 0.68 9.5 0.0 3.9 3 0 0 3 3 3 1 Kelch motif Cytochrom_D1 PF02239.11 ETO33912.1 - 0.0014 16.9 0.1 0.35 9.1 0.0 2.9 1 1 2 3 3 3 3 Cytochrome D1 heme domain DUF1797 PF08796.5 ETO33912.1 - 0.079 12.8 0.0 7.5 6.5 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1797) PD40 PF07676.7 ETO33912.1 - 0.095 12.3 7.5 14 5.4 0.1 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Kelch_2 PF07646.10 ETO33912.1 - 0.14 11.9 0.8 6.3 6.7 0.0 3.9 4 0 0 4 4 4 0 Kelch motif Proteasome_A_N PF10584.4 ETO33912.1 - 0.21 10.9 3.9 6 6.2 0.0 4.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Kelch_6 PF13964.1 ETO33912.1 - 0.22 11.7 7.4 11 6.3 0.0 5.2 7 0 0 7 7 7 0 Kelch motif LRS4 PF10422.4 ETO33913.1 - 0.084 12.2 7.5 0.13 11.5 5.2 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 HNOBA PF07701.9 ETO33913.1 - 0.11 11.7 2.8 0.14 11.3 2.0 1.1 1 0 0 1 1 1 0 Heme NO binding associated WD40 PF00400.27 ETO33916.1 - 1.5e-59 195.8 20.7 7.1e-15 54.2 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO33916.1 - 1.3e-06 27.0 0.6 0.012 13.9 0.0 3.0 3 0 0 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.3 ETO33916.1 - 4.8e-06 25.0 5.9 0.025 12.7 0.3 4.0 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO33916.1 - 5.1e-05 22.1 6.4 0.092 11.4 0.1 4.0 1 1 3 4 4 4 3 Nup133 N terminal like Resistin PF06954.6 ETO33916.1 - 0.0028 17.8 0.1 6.3 7.1 0.0 3.5 2 1 1 3 3 3 1 Resistin RVT_thumb PF06817.9 ETO33916.1 - 0.0085 15.6 0.1 20 4.8 0.0 3.4 3 0 0 3 3 3 0 Reverse transcriptase thumb domain RicinB_lectin_2 PF14200.1 ETO33916.1 - 0.085 13.2 0.0 0.45 10.9 0.0 2.1 1 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like PD40 PF07676.7 ETO33916.1 - 0.39 10.4 10.2 4.3 7.0 0.0 4.9 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat HSP70 PF00012.15 ETO33917.1 - 2.8e-07 28.8 0.1 0.00078 17.4 0.0 2.3 2 1 0 2 2 2 2 Hsp70 protein WD40 PF00400.27 ETO33918.1 - 1.5e-63 208.5 24.5 3.4e-10 39.3 0.8 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO33918.1 - 2.7e-09 35.7 6.5 0.031 12.4 0.0 5.4 2 1 2 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO33918.1 - 3.1e-06 26.2 4.1 0.22 10.2 0.0 4.4 1 1 2 4 4 4 3 Nup133 N terminal like WD40 PF00400.27 ETO33919.1 - 7.3e-53 174.6 21.5 3.9e-10 39.1 2.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO33919.1 - 6.6e-05 21.2 1.8 1.1 7.2 0.0 4.8 4 1 1 5 5 5 3 Nucleoporin Nup120/160 DUF4285 PF14113.1 ETO33920.1 - 0.085 12.8 1.0 0.12 12.3 0.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4285) DUF234 PF03008.9 ETO33920.1 - 0.093 12.8 0.3 0.11 12.6 0.2 1.3 1 0 0 1 1 1 0 Archaea bacterial proteins of unknown function tRNA_SAD PF07973.9 ETO33922.1 - 4.7e-08 32.7 0.9 1.2e-07 31.4 0.6 1.8 1 1 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Phage_glycop_gL PF11108.3 ETO33922.1 - 0.016 15.1 0.9 0.042 13.8 0.6 1.7 1 0 0 1 1 1 0 Viral glycoprotein L Peptidase_S74 PF13884.1 ETO33923.1 - 0.061 13.4 0.3 0.096 12.8 0.2 1.4 1 0 0 1 1 1 0 Chaperone of endosialidase SDA1 PF05285.7 ETO33924.1 - 1.8e-05 24.1 21.5 3.2e-05 23.3 14.9 1.4 1 0 0 1 1 1 1 SDA1 Trypan_PARP PF05887.6 ETO33924.1 - 0.9 9.3 17.0 0.12 12.1 8.0 2.0 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Thiolase_N PF00108.18 ETO33924.1 - 1.3 7.9 4.8 0.11 11.4 0.1 1.6 2 0 0 2 2 2 0 Thiolase, N-terminal domain DUF2457 PF10446.4 ETO33924.1 - 5.1 5.7 36.4 0.22 10.1 17.4 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2457) RGS PF00615.14 ETO33925.1 - 1.2e-07 31.8 0.1 0.0037 17.3 0.1 2.8 2 1 0 2 2 2 2 Regulator of G protein signaling domain Menin PF05053.8 ETO33925.1 - 0.47 8.5 9.1 0.75 7.8 6.3 1.2 1 0 0 1 1 1 0 Menin Striatin PF08232.7 ETO33925.1 - 4 7.7 15.6 0.38 11.0 3.1 3.2 3 0 0 3 3 3 0 Striatin family CDC45 PF02724.9 ETO33926.1 - 0.0099 13.9 6.8 0.01 13.8 4.7 1.1 1 0 0 1 1 1 1 CDC45-like protein F-box PF00646.28 ETO33927.1 - 0.0035 16.9 0.2 0.0097 15.5 0.0 1.9 2 0 0 2 2 2 1 F-box domain FliG_N PF14842.1 ETO33927.1 - 0.024 14.7 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 FliG N-terminal domain RSF PF14876.1 ETO33927.1 - 0.096 11.4 0.1 0.12 11.1 0.1 1.2 1 1 0 1 1 1 0 Respiratory growth transcriptional regulator F-box-like PF12937.2 ETO33927.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 F-box-like HrpJ PF07201.6 ETO33927.1 - 1.3 8.9 4.4 0.26 11.2 0.6 1.5 2 0 0 2 2 2 0 HrpJ-like domain Pkinase PF00069.20 ETO33928.1 - 0.00027 20.1 0.0 0.0006 19.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 ETO33929.1 - 1.3e-33 116.2 0.2 1.6e-20 73.3 0.0 2.9 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO33929.1 - 5.2e-26 91.2 0.0 5.1e-17 61.8 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 ETO33929.1 - 0.0078 15.1 0.0 0.14 11.1 0.0 2.2 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 ETO33929.1 - 0.084 11.9 1.6 0.09 11.8 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO33929.1 - 0.2 11.3 0.1 0.38 10.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family VWA_2 PF13519.1 ETO33931.1 - 2.1e-07 31.2 0.0 2.5e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Fibroin_P25 PF07294.6 ETO33931.1 - 0.026 14.0 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 Fibroin P25 Med25_VWA PF11265.3 ETO33931.1 - 0.091 11.7 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A WD40 PF00400.27 ETO33932.1 - 1.2e-62 205.6 22.3 5.4e-12 45.0 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO33932.1 - 1.3e-11 43.4 6.5 0.0061 14.7 0.0 5.8 1 1 5 6 6 6 6 Nucleoporin Nup120/160 DUF1690 PF07956.6 ETO33933.1 - 0.11 12.4 0.8 0.14 12.1 0.5 1.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) CamS PF07537.6 ETO33935.1 - 0.049 12.6 0.2 0.079 11.9 0.1 1.3 1 0 0 1 1 1 0 CamS sex pheromone cAM373 precursor WD40 PF00400.27 ETO33936.1 - 1.1e-28 98.0 10.4 1.9e-10 40.2 0.5 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO33936.1 - 1.8e-05 23.1 0.6 0.77 7.8 0.0 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 E_raikovi_mat PF06360.6 ETO33936.1 - 0.0053 16.9 1.4 0.064 13.4 0.1 2.7 3 0 0 3 3 3 1 Euplotes raikovi mating pheromone VEFS-Box PF09733.4 ETO33936.1 - 0.031 13.9 0.3 0.28 10.8 0.0 2.1 1 1 1 2 2 2 0 VEFS-Box of polycomb protein DUF3601 PF12208.3 ETO33936.1 - 0.061 13.2 0.0 4.3 7.3 0.0 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF3601) DUF1840 PF08895.6 ETO33937.1 - 0.056 13.4 2.7 0.081 12.9 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) DUF4203 PF13886.1 ETO33937.1 - 0.28 10.6 3.6 0.37 10.2 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) WD40 PF00400.27 ETO33938.1 - 1.5e-54 180.0 16.9 2.4e-11 43.0 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat PQQ_2 PF13360.1 ETO33938.1 - 1.7e-08 34.2 0.1 6.6e-08 32.3 0.1 2.3 1 1 0 1 1 1 1 PQQ-like domain eIF2A PF08662.6 ETO33938.1 - 2.5e-06 27.3 0.0 0.00042 20.0 0.0 2.6 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO33938.1 - 0.0019 16.3 4.6 0.17 9.9 0.1 3.5 1 1 2 3 3 3 2 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO33938.1 - 0.0025 17.7 0.0 5.1 7.1 0.0 3.8 2 1 2 4 4 4 2 Domain of unknown function (DUF3601) BBS2_Mid PF14783.1 ETO33938.1 - 0.094 12.5 0.3 11 5.8 0.0 3.6 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region DPPIV_N PF00930.16 ETO33938.1 - 0.1 11.1 0.2 8.3 4.8 0.0 2.6 1 1 1 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF3854 PF12965.2 ETO33941.1 - 0.016 14.8 0.2 0.028 14.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) Spore_III_AB PF09548.5 ETO33941.1 - 1.7 8.3 10.0 2 8.1 6.9 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) zf-like PF04071.7 ETO33941.1 - 6.1 6.6 7.4 1.1 8.9 2.1 1.9 1 1 1 2 2 2 0 Cysteine-rich small domain zf-TRAF PF02176.13 ETO33942.1 - 1.1e-06 28.8 3.5 1.1e-06 28.8 2.4 2.1 2 0 0 2 2 2 1 TRAF-type zinc finger Sec23_helical PF04815.10 ETO33942.1 - 0.00083 18.7 1.0 0.0023 17.3 0.7 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain DUF3210 PF11489.3 ETO33942.1 - 0.003 16.3 2.1 0.0032 16.2 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3210) FBA PF04300.8 ETO33942.1 - 0.067 13.1 2.4 0.11 12.4 1.7 1.5 1 1 0 1 1 1 0 F-box associated region Glyco_hydro_63 PF03200.11 ETO33942.1 - 0.16 9.7 13.9 0.18 9.6 9.6 1.2 1 0 0 1 1 1 0 Mannosyl oligosaccharide glucosidase zf-H2C2_5 PF13909.1 ETO33942.1 - 0.17 12.1 9.5 0.16 12.2 0.5 3.9 4 0 0 4 4 4 0 C2H2-type zinc-finger domain Unstab_antitox PF09720.5 ETO33942.1 - 0.25 11.0 2.8 0.26 11.0 0.9 1.8 2 0 0 2 2 2 0 Putative addiction module component Hom_end_hint PF05203.11 ETO33942.1 - 0.35 10.5 8.0 0.55 9.9 5.6 1.3 1 0 0 1 1 1 0 Hom_end-associated Hint DUF3482 PF11981.3 ETO33942.1 - 4.2 6.5 8.9 6.1 5.9 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) DivIVA PF05103.8 ETO33942.1 - 9.7 6.2 25.7 0.98 9.4 12.6 2.4 1 1 1 2 2 2 0 DivIVA protein CAP_N PF01213.14 ETO33943.1 - 1.5e-10 40.8 0.1 2.1e-10 40.4 0.0 1.4 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) N terminal DUF3909 PF13077.1 ETO33943.1 - 0.11 12.3 0.7 0.17 11.7 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3909) tRNA_lig_CPD PF08302.6 ETO33944.1 - 0.019 14.2 0.5 0.026 13.7 0.4 1.2 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain Apis_Csd PF11671.3 ETO33944.1 - 0.034 13.9 9.4 0.44 10.3 6.1 2.1 2 0 0 2 2 2 0 Complementary sex determiner protein DUF912 PF06024.7 ETO33944.1 - 0.31 11.1 5.3 0.56 10.2 3.7 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Secretin_N_2 PF07655.8 ETO33944.1 - 5.3 7.4 13.4 11 6.5 9.3 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Ras PF00071.17 ETO33945.1 - 4.8e-36 123.5 2.3 5.8e-26 90.8 0.1 2.6 3 0 0 3 3 3 2 Ras family Arf PF00025.16 ETO33945.1 - 1.3e-10 40.7 6.5 6.7e-07 28.6 0.0 3.1 3 0 0 3 3 3 2 ADP-ribosylation factor family Miro PF08477.8 ETO33945.1 - 5.5e-06 26.8 0.0 8.1e-05 23.0 0.0 2.6 1 1 0 1 1 1 1 Miro-like protein mRNA_cap_C PF03919.10 ETO33945.1 - 0.026 14.8 0.8 0.072 13.4 0.3 2.0 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain UPF0079 PF02367.12 ETO33945.1 - 0.063 12.8 0.2 0.36 10.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Exo_endo_phos PF03372.18 ETO33946.1 - 3.3e-11 43.6 1.8 7.2e-11 42.4 1.2 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 ETO33946.1 - 0.0038 16.8 1.3 0.014 14.9 0.9 2.0 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase FAA_hydrolase_N PF09298.6 ETO33948.1 - 7.1e-12 45.2 0.0 9e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Palm_thioest PF02089.10 ETO33948.1 - 0.00055 18.9 0.3 0.00086 18.3 0.2 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase zf-CCCH_2 PF14608.1 ETO33950.1 - 9.5 6.3 9.9 10 6.3 0.1 3.4 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type RabGAP-TBC PF00566.13 ETO33953.1 - 0.13 11.7 13.0 0.37 10.2 0.0 3.4 3 0 0 3 3 3 0 Rab-GTPase-TBC domain HEAT_2 PF13646.1 ETO33955.1 - 8.6e-15 54.8 0.0 6.3e-05 23.1 0.0 3.5 2 2 2 4 4 4 3 HEAT repeats HEAT PF02985.17 ETO33955.1 - 1.7e-14 52.5 0.0 0.018 15.0 0.0 6.4 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 ETO33955.1 - 3.1e-09 37.0 0.0 0.0088 16.5 0.0 3.5 4 1 1 5 5 4 2 HEAT-like repeat DUF3554 PF12074.3 ETO33955.1 - 1.1e-07 31.6 0.9 0.0056 16.1 0.0 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF3554) Cnd1 PF12717.2 ETO33955.1 - 1.6e-06 28.1 10.5 0.0021 17.9 0.0 3.5 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 MMS19_N PF14500.1 ETO33955.1 - 0.00054 19.3 3.0 0.0024 17.1 0.4 2.9 2 2 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II CLASP_N PF12348.3 ETO33955.1 - 0.00073 18.9 3.1 0.051 12.9 0.6 3.0 2 2 0 2 2 2 1 CLASP N terminal N_Asn_amidohyd PF14736.1 ETO33955.1 - 0.0055 15.5 1.8 0.035 12.9 0.1 2.4 2 0 0 2 2 2 1 Protein N-terminal asparagine amidohydrolase NLE PF08154.7 ETO33955.1 - 0.008 16.1 5.6 14 5.7 0.0 4.8 5 0 0 5 5 5 0 NLE (NUC135) domain DUF2222 PF09984.4 ETO33955.1 - 0.013 14.9 0.6 3 7.2 0.1 2.8 3 0 0 3 3 3 0 Uncharacterized signal transduction histidine kinase domain (DUF2222) DUF3137 PF11335.3 ETO33955.1 - 0.022 14.4 0.8 0.073 12.7 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3137) MMS19_C PF12460.3 ETO33955.1 - 0.025 13.2 11.4 0.011 14.5 2.4 2.8 1 1 0 2 2 2 0 RNAPII transcription regulator C-terminal TraC_F_IV PF11130.3 ETO33955.1 - 0.046 13.1 0.1 0.65 9.3 0.0 2.2 2 0 0 2 2 2 0 F pilus assembly Type-IV secretion system for plasmid transfer DUF1539 PF07560.6 ETO33955.1 - 0.047 13.5 2.5 0.16 11.7 0.6 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) HEAT_PBS PF03130.11 ETO33955.1 - 0.1 13.1 0.0 42 5.0 0.0 3.9 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat PBP1_TM PF14812.1 ETO33956.1 - 4.1 7.7 11.4 5.2 7.4 7.9 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_Ag35 PF03286.9 ETO33956.1 - 4.2 6.8 16.5 4.4 6.7 11.5 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Papo_T_antigen PF02380.10 ETO33958.1 - 1.8 8.5 8.0 0.12 12.3 0.9 2.3 3 0 0 3 3 3 0 T-antigen specific domain HEAT_2 PF13646.1 ETO33960.1 - 0.00063 19.9 0.0 0.031 14.5 0.0 2.7 1 1 1 2 2 2 2 HEAT repeats Cnd1 PF12717.2 ETO33960.1 - 0.0012 18.7 1.9 0.005 16.6 0.0 2.1 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 DS PF01916.12 ETO33960.1 - 0.073 12.1 0.1 0.13 11.3 0.1 1.4 1 0 0 1 1 1 0 Deoxyhypusine synthase SMN PF06003.7 ETO33961.1 - 0.2 10.7 11.5 0.22 10.5 8.0 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Spt5_N PF11942.3 ETO33961.1 - 8.9 7.0 20.6 11 6.7 14.3 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Anoctamin PF04547.7 ETO33962.1 - 0.0019 16.9 1.9 0.0021 16.8 1.3 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Bap31 PF05529.7 ETO33962.1 - 0.0045 16.4 2.7 0.005 16.3 1.9 1.2 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like YMF19 PF02326.10 ETO33962.1 - 0.018 15.5 5.6 0.026 15.0 3.5 1.7 1 1 0 1 1 1 0 Plant ATP synthase F0 FPN1 PF06963.7 ETO33962.1 - 0.021 13.1 0.2 0.024 13.0 0.1 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Potyvirid-P3 PF13608.1 ETO33962.1 - 0.032 13.3 6.3 0.036 13.1 4.4 1.0 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein UAA PF08449.6 ETO33962.1 - 0.053 12.4 1.4 0.077 11.9 1.0 1.2 1 0 0 1 1 1 0 UAA transporter family DUF4512 PF14975.1 ETO33962.1 - 0.088 13.6 1.2 0.14 13.0 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) WBP-1 PF11669.3 ETO33962.1 - 2 8.5 4.7 2.5 8.2 3.1 1.3 1 1 0 1 1 1 0 WW domain-binding protein 1 ETRAMP PF09716.5 ETO33962.1 - 2.8 7.9 6.2 5.2 7.0 4.0 1.8 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) ATP-synt_8 PF00895.15 ETO33962.1 - 6.7 7.0 7.8 0.45 10.7 0.3 2.5 3 1 0 3 3 3 0 ATP synthase protein 8 RGS PF00615.14 ETO33964.1 - 2.2e-05 24.5 0.0 6.3e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain NAD_binding_5 PF07994.7 ETO33965.1 - 1.8e-104 349.3 0.0 2.2e-104 349.1 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 ETO33965.1 - 2.6e-46 156.0 1.8 3.1e-46 155.8 0.2 2.0 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase PPR PF01535.15 ETO33967.1 - 1.4e-17 62.3 1.9 0.0037 17.1 0.0 4.9 4 0 0 4 4 4 4 PPR repeat PPR_2 PF13041.1 ETO33967.1 - 2.5e-16 59.3 5.7 4.7e-08 32.8 0.1 4.8 3 1 1 4 4 4 3 PPR repeat family PPR_1 PF12854.2 ETO33967.1 - 8.9e-12 44.2 1.6 0.01 15.2 0.0 4.5 4 0 0 4 4 4 4 PPR repeat PPR_3 PF13812.1 ETO33967.1 - 1.1e-10 40.9 0.0 0.042 14.1 0.0 4.8 5 0 0 5 5 5 3 Pentatricopeptide repeat domain LAGLIDADG_WhiA PF14527.1 ETO33967.1 - 2.6 7.9 6.5 9.4 6.1 0.0 2.9 3 0 0 3 3 3 0 WhiA LAGLIDADG-like domain CAF1 PF04857.15 ETO33968.1 - 8.8e-09 35.0 5.6 8.8e-09 35.0 3.9 3.0 2 1 0 2 2 2 1 CAF1 family ribonuclease POX PF07526.6 ETO33968.1 - 0.45 10.7 12.8 0.82 9.8 1.0 2.3 2 0 0 2 2 2 0 Associated with HOX Zip PF02535.17 ETO33968.1 - 2.3 7.1 6.3 5.7 5.8 0.5 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter RNA_pol_Rpc4 PF05132.9 ETO33968.1 - 5.1 7.0 15.0 0.36 10.8 1.5 2.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 Secretin_N_2 PF07655.8 ETO33968.1 - 5.7 7.4 24.5 0.43 11.0 10.2 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain CAF1 PF04857.15 ETO33969.1 - 1.9e-08 33.9 0.8 3.2e-08 33.2 0.6 1.4 1 0 0 1 1 1 1 CAF1 family ribonuclease bZIP_1 PF00170.16 ETO33971.1 - 0.013 15.3 6.8 1.1 9.2 0.3 2.5 2 0 0 2 2 2 0 bZIP transcription factor NPV_P10 PF05531.7 ETO33971.1 - 0.014 15.6 4.0 0.014 15.6 2.8 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CAGE1 PF15066.1 ETO33971.1 - 0.025 13.0 15.5 0.017 13.6 1.7 2.1 1 1 1 2 2 2 0 Cancer-associated gene protein 1 family Geminin PF07412.7 ETO33971.1 - 0.035 13.8 6.1 0.27 10.8 0.5 2.2 2 0 0 2 2 2 0 Geminin Pox_A_type_inc PF04508.7 ETO33971.1 - 0.078 12.7 5.4 0.5 10.2 0.1 4.0 3 1 2 5 5 5 0 Viral A-type inclusion protein repeat Cut12 PF11500.3 ETO33971.1 - 0.099 12.3 3.5 0.068 12.8 1.1 1.7 1 1 0 1 1 1 0 Spindle pole body formation-associated protein DUF964 PF06133.6 ETO33971.1 - 0.12 12.3 10.2 1 9.3 2.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF964) DUF641 PF04859.7 ETO33971.1 - 0.14 11.9 8.1 0.038 13.7 2.2 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) TMF_TATA_bd PF12325.3 ETO33971.1 - 0.14 11.8 10.8 1.1 8.9 7.5 2.1 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 ETO33971.1 - 0.18 11.3 11.4 0.34 10.4 7.9 1.4 1 1 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 ETO33971.1 - 0.23 11.3 18.9 0.75 9.6 5.6 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.4 ETO33971.1 - 0.28 11.0 15.5 0.53 10.1 6.5 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DnaB_C PF03796.10 ETO33971.1 - 0.32 9.8 7.1 1.3 7.8 4.8 1.8 1 1 1 2 2 2 0 DnaB-like helicase C terminal domain Fez1 PF06818.10 ETO33971.1 - 0.33 10.9 6.8 2.6 8.0 4.6 2.0 1 1 0 1 1 1 0 Fez1 YscO PF07321.7 ETO33971.1 - 0.46 10.2 4.1 0.25 11.1 0.8 1.8 2 0 0 2 2 2 0 Type III secretion protein YscO DivIC PF04977.10 ETO33971.1 - 0.82 9.1 12.1 1.6 8.3 3.1 2.5 2 0 0 2 2 2 0 Septum formation initiator DUF904 PF06005.7 ETO33971.1 - 0.97 9.7 12.7 0.24 11.7 0.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF904) Tropomyosin_1 PF12718.2 ETO33971.1 - 2.5 7.9 15.3 46 3.8 11.0 2.1 1 1 1 2 2 2 0 Tropomyosin like EcoEI_R_C PF08463.5 ETO33971.1 - 2.9 7.7 10.1 0.88 9.4 0.9 2.7 1 1 1 2 2 2 0 EcoEI R protein C-terminal DUF4200 PF13863.1 ETO33971.1 - 5.3 7.0 17.9 2.2 8.2 5.0 3.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4200) DUF972 PF06156.8 ETO33971.1 - 8.3 6.8 10.7 15 6.0 2.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) WD40 PF00400.27 ETO33972.1 - 3.6e-12 45.6 6.7 4e-11 42.3 0.1 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF484 PF04340.7 ETO33972.1 - 0.085 12.3 0.3 0.16 11.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF484 EIIBC-GUT_N PF03612.9 ETO33972.1 - 8.7 5.9 10.2 11 5.6 2.0 2.7 3 0 0 3 3 3 0 Sorbitol phosphotransferase enzyme II N-terminus DUF373 PF04123.8 ETO33974.1 - 0.019 14.0 4.0 0.029 13.4 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF3439 PF11921.3 ETO33976.1 - 3 7.6 7.6 4.1 7.1 2.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF869 PF05911.6 ETO33977.1 - 0.0039 15.4 2.5 0.0045 15.3 1.7 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) MGAT2 PF05060.9 ETO33977.1 - 0.026 13.4 0.4 0.049 12.5 0.2 1.6 1 1 0 1 1 1 0 N-acetylglucosaminyltransferase II (MGAT2) FlgN PF05130.7 ETO33977.1 - 0.1 12.8 4.0 0.19 11.9 2.7 1.5 1 1 0 1 1 1 0 FlgN protein zf-TRAF PF02176.13 ETO33978.1 - 0.015 15.6 0.0 0.015 15.6 0.0 2.4 3 0 0 3 3 3 0 TRAF-type zinc finger DUF723 PF05265.8 ETO33978.1 - 0.11 12.3 1.0 17 5.3 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF723) zf-C3HC4_4 PF15227.1 ETO33978.1 - 0.61 10.0 4.9 0.62 9.9 0.5 3.0 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 ETO33978.1 - 3 7.7 8.4 0.92 9.3 2.0 2.9 2 2 0 2 2 2 0 Ring finger domain zf-rbx1 PF12678.2 ETO33978.1 - 3.1 7.9 9.7 1.9 8.6 2.6 3.1 2 2 1 3 3 3 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 ETO33978.1 - 3.8 7.6 8.8 3.9 7.5 2.0 3.4 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Peptidase_C14 PF00656.17 ETO33979.1 - 0.11 12.1 0.0 0.12 12.0 0.0 1.2 1 1 0 1 1 1 0 Caspase domain Toprim_Crpt PF13342.1 ETO33982.1 - 0.028 14.0 0.3 0.098 12.3 0.2 2.0 1 1 0 1 1 1 0 C-terminal repeat of topoisomerase Phasin PF05597.6 ETO33982.1 - 0.14 11.9 4.5 4.6 7.0 0.9 3.3 1 1 3 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Transferase PF02458.10 ETO33982.1 - 0.25 9.7 6.0 0.038 12.4 0.2 1.9 2 0 0 2 2 2 0 Transferase family DUF2115 PF09888.4 ETO33982.1 - 5.3 7.1 10.7 0.96 9.5 0.2 2.8 2 1 2 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2115) WD40 PF00400.27 ETO33985.1 - 8.4e-44 145.9 9.3 5e-14 51.5 0.1 4.0 4 0 0 4 4 4 4 WD domain, G-beta repeat eIF2A PF08662.6 ETO33985.1 - 3.8e-08 33.2 0.2 6.4e-06 25.9 0.0 1.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO33985.1 - 4.3e-06 25.1 0.6 0.032 12.3 0.0 2.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF1258 PF06869.7 ETO33985.1 - 0.0026 16.9 0.9 2.1 7.3 0.0 2.7 1 1 2 3 3 3 2 Protein of unknown function (DUF1258) Nucleoporin_N PF08801.6 ETO33985.1 - 0.0067 15.2 3.1 2.1 6.9 0.0 3.3 1 1 1 3 3 3 2 Nup133 N terminal like Resistin PF06954.6 ETO33985.1 - 0.046 13.9 0.0 3.5 7.9 0.0 2.6 1 1 2 3 3 3 0 Resistin DUF4072 PF13284.1 ETO33985.1 - 0.059 13.5 0.0 0.27 11.4 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4072) PD40 PF07676.7 ETO33985.1 - 0.072 12.7 0.2 10 5.8 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat GOLD_2 PF13897.1 ETO33986.1 - 0.3 11.3 1.3 0.42 10.8 0.2 1.8 1 1 1 2 2 2 0 Golgi-dynamics membrane-trafficking YL1 PF05764.8 ETO33986.1 - 0.93 9.0 9.2 1.6 8.3 6.4 1.3 1 1 0 1 1 1 0 YL1 nuclear protein Ubiquitin_3 PF14836.1 ETO33987.1 - 0.11 12.1 0.1 0.15 11.7 0.0 1.4 1 1 0 1 1 1 0 Ubiquitin-like domain DUF912 PF06024.7 ETO33988.1 - 0.3 11.1 1.9 7.4 6.6 0.1 2.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) AP_endonuc_2_N PF07582.7 ETO33991.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 AP endonuclease family 2 C terminus LAGLIDADG_1 PF00961.14 ETO33992.1 - 4.1 8.0 15.3 6 7.4 3.0 2.2 2 0 0 2 2 2 0 LAGLIDADG endonuclease NACHT PF05729.7 ETO33993.1 - 4.1e-12 46.0 0.0 1.3e-10 41.2 0.0 2.2 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 ETO33993.1 - 1.7e-05 23.7 0.1 0.0016 17.3 0.1 2.5 1 1 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.17 ETO33993.1 - 0.0056 16.8 2.9 0.061 13.4 0.1 2.6 2 1 0 2 2 2 1 RNA helicase AAA_16 PF13191.1 ETO33993.1 - 0.006 16.5 0.0 0.13 12.2 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain KaiC PF06745.8 ETO33993.1 - 0.013 14.6 0.1 0.04 13.0 0.1 1.8 1 1 0 1 1 1 0 KaiC AAA_22 PF13401.1 ETO33993.1 - 0.014 15.5 0.4 0.055 13.6 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 ETO33993.1 - 0.026 14.7 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 ETO33993.1 - 0.039 12.9 0.1 0.039 12.9 0.1 2.5 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2075) Miro PF08477.8 ETO33993.1 - 0.043 14.2 0.7 0.095 13.1 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein AAA_30 PF13604.1 ETO33993.1 - 0.067 12.7 0.2 0.38 10.3 0.0 2.0 1 1 1 2 2 2 0 AAA domain RPAP3_C PF13877.1 ETO33993.1 - 0.096 12.6 2.0 0.3 11.0 0.1 2.3 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 AAA_17 PF13207.1 ETO33993.1 - 0.72 10.6 3.1 1.2 9.9 0.1 2.4 2 1 0 2 2 2 0 AAA domain Ribosomal_L6 PF00347.18 ETO33994.1 - 9.7e-12 45.2 2.3 0.0004 20.8 0.0 4.2 2 2 0 3 3 3 3 Ribosomal protein L6 DUF1029 PF06269.7 ETO33994.1 - 0.8 9.7 6.0 1.7 8.7 1.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1029) DUF4419 PF14388.1 ETO33995.1 - 0.046 12.9 0.1 0.05 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4419) CAP_GLY PF01302.20 ETO33996.1 - 0.00047 19.8 3.5 0.78 9.4 0.2 3.5 1 1 2 3 3 3 3 CAP-Gly domain DUF603 PF04645.7 ETO33997.1 - 0.059 13.3 4.9 0.11 12.4 3.4 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF603 DUF2452 PF10504.4 ETO33997.1 - 0.56 9.4 6.2 1.9 7.7 2.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2452) Chordopox_A33R PF05966.7 ETO33998.1 - 0.018 13.8 0.2 0.019 13.7 0.1 1.1 1 0 0 1 1 1 0 Chordopoxvirus A33R protein DUF1676 PF07898.8 ETO33998.1 - 0.018 15.3 1.1 0.026 14.8 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) DUF2615 PF11027.3 ETO33998.1 - 0.018 14.9 3.2 0.025 14.5 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) DUF2031 PF09592.5 ETO33998.1 - 0.065 12.3 0.6 0.069 12.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) Herpes_US9 PF06072.6 ETO33998.1 - 0.082 12.7 1.2 0.12 12.2 0.9 1.2 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF4179 PF13786.1 ETO33998.1 - 0.12 12.5 1.2 0.18 12.0 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) DUF2116 PF09889.4 ETO33998.1 - 1.2 8.9 8.7 2 8.2 6.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) EpsG PF14897.1 ETO33998.1 - 2.1 7.2 5.2 2.6 6.8 3.6 1.0 1 0 0 1 1 1 0 EpsG family HEAT PF02985.17 ETO33999.1 - 0.094 12.8 0.0 7.1 7.0 0.0 2.5 2 0 0 2 2 2 0 HEAT repeat Rot1 PF10681.4 ETO33999.1 - 0.098 11.9 0.2 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal Laminin_EGF PF00053.19 ETO33999.1 - 0.33 10.9 2.7 0.94 9.4 0.1 2.2 2 0 0 2 2 2 0 Laminin EGF-like (Domains III and V) HEAT PF02985.17 ETO34000.1 - 0.013 15.4 0.1 0.11 12.6 0.0 2.4 2 0 0 2 2 2 0 HEAT repeat HEAT_2 PF13646.1 ETO34000.1 - 0.034 14.4 0.0 0.086 13.1 0.0 1.7 1 0 0 1 1 1 0 HEAT repeats KilA-N PF04383.8 ETO34001.1 - 0.0039 16.7 0.1 0.0045 16.6 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain LtrA PF06772.6 ETO34002.1 - 0.052 12.4 0.1 0.056 12.3 0.1 1.0 1 0 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) Noc2 PF03715.8 ETO34002.1 - 0.11 11.3 1.7 0.11 11.3 1.2 1.0 1 0 0 1 1 1 0 Noc2p family DUF1473 PF07341.6 ETO34002.1 - 0.13 11.7 1.4 0.15 11.6 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1473) DUF972 PF06156.8 ETO34003.1 - 0.041 14.2 1.1 0.1 12.9 0.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DNA_pol_phi PF04931.8 ETO34004.1 - 0.0098 13.7 1.4 0.012 13.4 0.9 1.1 1 0 0 1 1 1 1 DNA polymerase phi SPT16 PF08644.6 ETO34005.1 - 4.3e-39 133.7 0.0 4.3e-39 133.7 0.0 3.5 4 0 0 4 4 4 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.19 ETO34005.1 - 2e-22 79.7 0.0 4e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 FACT-Spt16_Nlob PF14826.1 ETO34005.1 - 3.4e-21 75.4 0.1 3.4e-21 75.4 0.1 2.7 3 0 0 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain Rtt106 PF08512.7 ETO34005.1 - 3.9e-19 68.4 0.0 1.7e-18 66.3 0.0 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Daxx PF03344.10 ETO34006.1 - 0.53 8.6 26.7 0.63 8.4 18.5 1.0 1 0 0 1 1 1 0 Daxx Family Zip PF02535.17 ETO34006.1 - 1.1 8.1 2.5 1.5 7.7 1.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SPRY PF00622.23 ETO34007.1 - 0.011 15.7 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 0 SPRY domain DUF190 PF02641.10 ETO34008.1 - 0.077 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized ACR, COG1993 OB_NTP_bind PF07717.11 ETO34009.1 - 1.5e-28 98.9 0.0 3.8e-28 97.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 ETO34009.1 - 1.3e-22 79.7 0.8 2.8e-22 78.6 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 ETO34009.1 - 2.1e-13 49.9 0.0 7.3e-13 48.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETO34009.1 - 2.3e-07 30.4 0.1 9.9e-07 28.4 0.1 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 ETO34009.1 - 6.8e-05 23.0 0.3 0.00069 19.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.9 ETO34009.1 - 0.048 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AA_permease PF00324.16 ETO34010.1 - 4.6e-14 51.6 16.9 5.2e-14 51.4 11.7 1.1 1 0 0 1 1 1 1 Amino acid permease HALZ PF02183.13 ETO34010.1 - 5.3e-05 22.8 0.0 9.3e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper Nnf1 PF03980.9 ETO34010.1 - 0.01 15.7 0.4 0.015 15.2 0.3 1.1 1 0 0 1 1 1 0 Nnf1 AA_permease_2 PF13520.1 ETO34010.1 - 0.042 12.3 16.1 0.051 12.0 11.2 1.1 1 0 0 1 1 1 0 Amino acid permease DUF641 PF04859.7 ETO34010.1 - 0.12 12.1 0.3 0.17 11.6 0.2 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) bZIP_1 PF00170.16 ETO34010.1 - 0.13 12.1 0.1 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 bZIP transcription factor PUF PF00806.14 ETO34011.1 - 1.7e-29 99.6 11.2 2.6e-06 26.5 0.0 6.4 6 0 0 6 6 6 6 Pumilio-family RNA binding repeat MMS19_C PF12460.3 ETO34011.1 - 0.0057 15.4 1.3 0.0057 15.4 0.9 1.6 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal RNA_pol_Rpb1_5 PF04998.12 ETO34012.1 - 6.2e-43 147.0 19.4 3.7e-39 134.6 13.4 3.4 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 Hid1 PF12722.2 ETO34012.1 - 2.6 5.5 23.3 4 4.9 16.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RNA_pol_Rpb1_5 PF04998.12 ETO34013.1 - 2e-33 115.8 0.0 2.8e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_4 PF05000.12 ETO34013.1 - 7.3e-22 77.1 0.0 2.3e-21 75.5 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_3 PF04983.13 ETO34013.1 - 1.4e-11 44.3 0.0 5.1e-11 42.5 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_2 PF00623.15 ETO34014.1 - 5.8e-39 133.6 0.2 8.7e-39 133.1 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 ETO34014.1 - 1.4e-18 67.0 0.0 3e-18 66.0 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 DUF1018 PF06252.7 ETO34015.1 - 3.1 8.3 8.7 2.8 8.4 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1018) zf-RING_5 PF14634.1 ETO34016.1 - 0.067 12.9 0.5 0.067 12.9 0.4 2.8 2 0 0 2 2 2 0 zinc-RING finger domain BBS2_N PF14781.1 ETO34017.1 - 0.041 13.5 0.3 0.046 13.3 0.2 1.3 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal VirK PF06903.7 ETO34017.1 - 0.075 12.7 0.5 0.12 12.1 0.4 1.4 1 1 0 1 1 1 0 VirK protein Atrophin-1 PF03154.10 ETO34018.1 - 0.0025 16.0 5.6 0.0053 14.9 3.9 1.5 1 0 0 1 1 1 1 Atrophin-1 family Topoisom_bac PF01131.15 ETO34020.1 - 1.5e-78 264.3 0.1 2.8e-78 263.5 0.0 1.3 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 ETO34020.1 - 5.6e-16 58.3 0.0 2.9e-15 56.0 0.0 2.1 2 0 0 2 2 2 1 Toprim domain Peptidase_C14 PF00656.17 ETO34021.1 - 4.9e-13 49.3 2.4 4.2e-12 46.3 1.6 2.0 1 1 0 1 1 1 1 Caspase domain Kelch_5 PF13854.1 ETO34022.1 - 5.3e-06 26.2 0.4 0.0054 16.6 0.2 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 ETO34022.1 - 4e-05 23.6 0.0 0.00016 21.7 0.0 1.8 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO34022.1 - 0.00043 20.3 1.1 0.0054 16.8 0.1 2.2 1 1 1 2 2 2 1 Kelch motif Kelch_4 PF13418.1 ETO34022.1 - 0.00082 19.1 0.0 0.028 14.1 0.0 2.3 2 0 0 2 2 2 1 Galactose oxidase, central domain Erv26 PF04148.8 ETO34022.1 - 0.018 14.4 0.7 0.038 13.3 0.5 1.5 1 1 0 1 1 1 0 Transmembrane adaptor Erv26 Kelch_2 PF07646.10 ETO34022.1 - 0.029 14.1 0.2 2 8.3 0.1 2.5 2 0 0 2 2 2 0 Kelch motif Kelch_1 PF01344.20 ETO34022.1 - 0.046 13.2 0.0 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 Kelch motif SOR_SNZ PF01680.12 ETO34023.1 - 7.7e-101 335.9 3.5 1e-100 335.5 2.4 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 ETO34023.1 - 7.7e-10 38.2 2.5 2.1e-07 30.2 0.1 2.4 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG NMO PF03060.10 ETO34023.1 - 5.4e-06 25.7 3.2 0.00042 19.5 0.1 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase Dus PF01207.12 ETO34023.1 - 0.00067 18.5 0.2 0.39 9.4 0.0 2.4 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.9 ETO34023.1 - 0.00081 18.4 0.7 0.016 14.1 0.0 2.6 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.16 ETO34023.1 - 0.0009 18.5 0.1 0.0052 16.0 0.0 2.0 2 0 0 2 2 2 1 Histidine biosynthesis protein ETF PF01012.16 ETO34023.1 - 0.001 18.8 0.4 0.056 13.1 0.1 2.4 2 0 0 2 2 2 1 Electron transfer flavoprotein domain FMN_dh PF01070.13 ETO34023.1 - 0.0071 15.2 1.4 0.027 13.3 0.0 2.4 4 0 0 4 4 4 1 FMN-dependent dehydrogenase IMPDH PF00478.20 ETO34023.1 - 0.0077 15.1 0.0 0.015 14.1 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 ETO34023.1 - 0.0077 15.1 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IGPS PF00218.16 ETO34023.1 - 0.047 12.7 0.1 0.29 10.1 0.0 2.2 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase DHO_dh PF01180.16 ETO34023.1 - 0.06 12.2 0.1 0.15 11.0 0.0 1.6 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase DUF2608 PF11019.3 ETO34024.1 - 7.4e-08 31.6 10.4 2e-07 30.2 2.1 2.9 1 1 1 2 2 2 2 Protein of unknown function (DUF2608) RRM_6 PF14259.1 ETO34025.1 - 2.4e-13 49.8 1.1 1.1e-09 38.0 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO34025.1 - 5.5e-10 38.7 2.0 1.7e-09 37.2 0.1 2.5 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO34025.1 - 0.031 14.1 0.6 0.073 12.9 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EMP24_GP25L PF01105.19 ETO34027.1 - 3.1e-10 40.0 0.3 4e-10 39.7 0.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF3244 PF11589.3 ETO34027.1 - 0.02 14.5 0.2 0.033 13.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3244) CHU_C PF13585.1 ETO34027.1 - 0.042 13.7 0.2 0.097 12.5 0.1 1.5 1 1 0 1 1 1 0 C-terminal domain of CHU protein family NACHT PF05729.7 ETO34029.1 - 0.0033 17.0 0.0 0.0046 16.6 0.0 1.1 1 0 0 1 1 1 1 NACHT domain UPF0121 PF03661.8 ETO34029.1 - 0.14 11.3 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0121) EF-hand_1 PF00036.27 ETO34029.1 - 0.45 9.9 4.1 0.22 10.9 1.0 1.9 2 0 0 2 2 2 0 EF hand NACHT PF05729.7 ETO34030.1 - 0.00022 20.9 0.0 0.00056 19.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETO34030.1 - 0.00036 20.6 0.0 0.00093 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETO34030.1 - 0.0013 19.0 4.2 0.0053 17.0 0.0 2.9 2 1 0 3 3 3 1 AAA domain G-alpha PF00503.15 ETO34030.1 - 0.0018 17.0 2.2 0.0018 17.0 1.5 1.7 1 1 0 1 1 1 1 G-protein alpha subunit AAA_17 PF13207.1 ETO34030.1 - 0.0034 18.1 0.7 0.079 13.7 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 ETO34030.1 - 0.0087 15.7 0.1 0.21 11.3 0.0 2.7 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 ETO34030.1 - 0.014 14.4 0.0 0.03 13.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 ETO34030.1 - 0.021 15.0 0.0 0.058 13.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.21 ETO34030.1 - 0.023 14.1 0.0 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain UPF0079 PF02367.12 ETO34030.1 - 0.026 14.1 0.0 0.085 12.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 ETO34030.1 - 0.079 12.1 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 T2SE PF00437.15 ETO34030.1 - 0.088 11.6 0.2 0.38 9.6 0.1 2.1 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 ETO34030.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RRM_6 PF14259.1 ETO34031.1 - 8.3e-05 22.4 0.1 0.071 13.1 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO34031.1 - 0.00048 19.6 0.0 0.32 10.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRP7 PF12923.2 ETO34031.1 - 0.0067 16.4 2.8 0.0067 16.4 2.0 2.4 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) Kelch_1 PF01344.20 ETO34032.1 - 0.00013 21.4 1.4 0.00067 19.1 0.5 2.1 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETO34032.1 - 0.0093 16.1 0.5 0.83 9.9 0.1 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 ETO34032.1 - 0.068 12.9 0.2 0.9 9.3 0.0 2.2 2 0 0 2 2 2 0 Galactose oxidase, central domain zf-C2H2_4 PF13894.1 ETO34033.1 - 0.00047 20.2 12.5 0.058 13.7 0.5 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETO34033.1 - 0.0019 18.3 13.8 0.0033 17.6 0.4 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 ETO34033.1 - 2.5 8.6 14.1 0.4 11.1 0.7 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type EOS1 PF12326.3 ETO34034.1 - 0.0047 16.5 1.7 0.0076 15.9 1.2 1.4 1 0 0 1 1 1 1 N-glycosylation protein Bacteroid_pep PF14406.1 ETO34034.1 - 0.94 9.6 6.2 0.28 11.3 0.5 2.5 2 0 0 2 2 2 0 Ribosomally synthesized peptide in Bacteroidetes zf-LYAR PF08790.6 ETO34035.1 - 0.038 13.6 1.1 0.038 13.6 0.7 2.1 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Coatamer_beta_C PF07718.7 ETO34036.1 - 0.034 13.7 0.5 0.046 13.3 0.4 1.2 1 0 0 1 1 1 0 Coatomer beta C-terminal region Kelch_4 PF13418.1 ETO34037.1 - 0.00015 21.4 2.3 0.091 12.5 0.1 4.1 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO34037.1 - 0.0012 18.4 8.3 6 6.7 0.0 5.0 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO34037.1 - 0.0026 17.2 4.1 9.3 5.8 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO34037.1 - 0.0045 17.1 6.6 1.3 9.3 0.0 4.5 4 1 1 5 5 5 1 Kelch motif CAMSAP_CKK PF08683.6 ETO34037.1 - 0.096 12.3 6.7 1 9.0 2.5 2.8 2 1 0 2 2 2 0 Microtubule-binding calmodulin-regulated spectrin-associated Kelch_5 PF13854.1 ETO34037.1 - 0.44 10.5 9.7 1.4 8.9 0.0 4.1 4 1 1 5 5 5 0 Kelch motif DND1_DSRM PF14709.1 ETO34039.1 - 0.08 13.2 0.4 0.62 10.3 0.0 2.2 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 Intg_mem_TP0381 PF09529.5 ETO34041.1 - 0.054 12.7 5.5 0.12 11.6 1.2 2.1 2 0 0 2 2 2 0 Integral membrane protein (intg_mem_TP0381) PSI_PsaE PF02427.12 ETO34041.1 - 0.065 12.6 0.1 0.14 11.5 0.1 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IV / PsaE DUF1510 PF07423.6 ETO34041.1 - 6.5 6.0 22.4 13 5.0 15.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) LRR_1 PF00560.28 ETO34042.1 - 0.11 12.6 1.0 4.1 7.8 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich Repeat Epimerase PF01370.16 ETO34043.1 - 2.1e-10 40.4 0.0 4.1e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETO34043.1 - 1e-09 38.6 0.0 1.4e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 ETO34043.1 - 1.6e-05 24.8 0.0 2.3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 ETO34043.1 - 0.00027 19.7 0.0 0.00035 19.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 ETO34043.1 - 0.0047 15.8 0.0 0.0073 15.2 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 ETO34043.1 - 0.0062 15.8 0.0 0.015 14.5 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family 3HCDH_N PF02737.13 ETO34043.1 - 0.017 14.7 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.5 ETO34043.1 - 0.12 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 KR domain DUF3535 PF12054.3 ETO34044.1 - 0.037 12.6 0.5 0.42 9.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3535) HEAT_2 PF13646.1 ETO34044.1 - 0.04 14.2 0.0 0.17 12.1 0.0 2.0 1 1 1 2 2 2 0 HEAT repeats DUF2937 PF11157.3 ETO34044.1 - 0.073 12.4 1.0 0.15 11.4 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Aldedh PF00171.17 ETO34045.1 - 3.9e-68 229.8 0.3 4.7e-68 229.5 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RmlD_sub_bind PF04321.12 ETO34047.1 - 1.2e-15 57.1 0.0 2.2e-12 46.4 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain Epimerase PF01370.16 ETO34047.1 - 1.5e-05 24.5 0.0 4.2e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ETO34047.1 - 0.036 12.9 0.1 0.16 10.8 0.0 1.9 1 1 1 2 2 2 0 Male sterility protein Epimerase PF01370.16 ETO34048.1 - 9.4e-05 21.9 0.0 0.0022 17.4 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ETO34048.1 - 0.027 13.3 0.0 0.053 12.4 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Semialdhyde_dh PF01118.19 ETO34048.1 - 0.031 14.5 0.0 0.078 13.2 0.0 1.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 ETO34048.1 - 0.035 13.3 0.0 3.5 6.8 0.0 2.3 2 1 0 2 2 2 0 NmrA-like family G-alpha PF00503.15 ETO34049.1 - 1.4e-17 63.5 2.2 1.5e-17 63.3 1.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Rad17 PF03215.10 ETO34049.1 - 0.0047 15.6 0.8 0.0058 15.3 0.6 1.0 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein Arf PF00025.16 ETO34049.1 - 0.01 15.0 0.0 0.021 14.0 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETO34049.1 - 0.011 15.6 0.1 0.018 14.9 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 ETO34049.1 - 0.016 15.6 0.4 0.026 15.0 0.1 1.6 2 1 0 2 2 1 0 Miro-like protein FeoB_N PF02421.13 ETO34049.1 - 0.028 13.7 0.2 0.36 10.0 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B Septin PF00735.13 ETO34049.1 - 0.038 13.0 0.2 0.048 12.6 0.1 1.2 1 0 0 1 1 1 0 Septin MutS_V PF00488.16 ETO34049.1 - 0.041 13.2 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 MutS domain V AAA_23 PF13476.1 ETO34049.1 - 0.067 13.5 0.3 0.067 13.5 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 ETO34049.1 - 0.091 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 ETO34049.1 - 0.098 12.5 0.0 0.16 11.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 ETO34049.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMPL PF03176.10 ETO34051.1 - 9.6e-57 192.1 7.3 2.2e-28 98.9 0.0 2.4 2 1 0 2 2 2 2 MMPL family ACR_tran PF00873.14 ETO34051.1 - 0.17 9.2 10.5 0.043 11.2 1.9 2.5 3 0 0 3 3 3 0 AcrB/AcrD/AcrF family DUF4027 PF13219.1 ETO34052.1 - 0.12 11.7 1.6 0.26 10.7 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) Atg14 PF10186.4 ETO34053.1 - 0.0034 16.3 4.6 0.0054 15.7 3.2 1.4 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 ATG16 PF08614.6 ETO34053.1 - 0.0087 15.8 8.2 0.014 15.1 5.7 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) CCDC155 PF14662.1 ETO34053.1 - 0.015 14.9 7.9 0.026 14.0 5.5 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 IncA PF04156.9 ETO34053.1 - 0.017 14.6 7.6 0.026 14.1 5.3 1.3 1 0 0 1 1 1 0 IncA protein Rootletin PF15035.1 ETO34053.1 - 0.054 13.4 9.4 0.084 12.8 6.5 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF4164 PF13747.1 ETO34053.1 - 1.2 9.3 5.4 1 9.5 0.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) zf-C2H2_4 PF13894.1 ETO34056.1 - 0.065 13.5 0.8 0.15 12.4 0.6 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger Exonuc_VII_L PF02601.10 ETO34057.1 - 0.67 9.0 8.3 0.71 9.0 5.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit RGS PF00615.14 ETO34058.1 - 5.9e-08 32.8 2.9 8.1e-08 32.3 2.0 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain Tubulin PF00091.20 ETO34061.1 - 1.5e-61 208.0 0.0 2e-61 207.5 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO34061.1 - 1e-31 109.6 0.0 1.8e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.1 ETO34061.1 - 0.073 11.9 0.9 0.27 10.1 0.4 1.8 1 1 1 2 2 2 0 Tubulin like TPR_12 PF13424.1 ETO34063.1 - 2.6e-199 645.7 61.5 2.4e-25 88.2 0.1 10.3 5 5 6 11 11 11 11 Tetratricopeptide repeat TPR_1 PF00515.23 ETO34063.1 - 2.9e-112 362.1 115.2 1.5e-10 40.2 1.4 16.2 16 0 0 16 16 16 14 Tetratricopeptide repeat TPR_11 PF13414.1 ETO34063.1 - 1.4e-108 354.6 76.2 1.6e-16 59.6 0.8 9.2 7 1 3 10 10 10 10 TPR repeat TPR_2 PF07719.12 ETO34063.1 - 2.2e-95 305.0 77.8 2.6e-08 33.1 0.2 16.2 16 0 0 16 16 16 14 Tetratricopeptide repeat TPR_7 PF13176.1 ETO34063.1 - 3.5e-91 291.9 38.7 1.1e-08 34.2 0.2 16.1 16 0 0 16 16 16 14 Tetratricopeptide repeat TPR_10 PF13374.1 ETO34063.1 - 6.6e-84 273.7 0.0 3.8e-07 29.8 0.0 16.0 16 0 0 16 16 16 13 Tetratricopeptide repeat TPR_8 PF13181.1 ETO34063.1 - 1.6e-82 265.2 130.5 2.9e-07 29.7 1.0 15.9 16 0 0 16 16 16 14 Tetratricopeptide repeat TPR_17 PF13431.1 ETO34063.1 - 1.4e-46 152.8 44.0 0.0014 18.6 0.1 16.4 15 1 0 15 15 15 13 Tetratricopeptide repeat TPR_14 PF13428.1 ETO34063.1 - 1.3e-39 131.0 0.0 0.012 16.1 0.0 14.2 13 2 2 15 15 14 8 Tetratricopeptide repeat TPR_16 PF13432.1 ETO34063.1 - 5e-36 122.6 0.0 4.4e-05 24.0 0.1 10.2 5 4 3 9 9 9 7 Tetratricopeptide repeat TPR_6 PF13174.1 ETO34063.1 - 3.3e-33 111.8 29.6 0.02 15.3 0.1 14.9 16 0 0 16 16 15 9 Tetratricopeptide repeat Apc3 PF12895.2 ETO34063.1 - 3.7e-22 78.2 59.2 9.7e-05 22.4 5.1 9.6 1 1 10 11 11 11 11 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO34063.1 - 1.4e-18 66.9 18.7 0.00078 19.7 0.0 9.3 2 2 9 12 12 12 8 Tetratricopeptide repeat MIT PF04212.13 ETO34063.1 - 4.1e-17 61.8 62.1 0.042 13.7 0.1 13.6 14 1 0 14 14 13 9 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.4 ETO34063.1 - 3.4e-15 54.9 17.8 0.6 9.3 0.0 11.9 14 0 0 14 14 13 3 SHNi-TPR TPR_3 PF07720.7 ETO34063.1 - 4.7e-12 45.4 71.6 0.053 13.3 0.3 13.9 14 0 0 14 14 14 6 Tetratricopeptide repeat Sel1 PF08238.7 ETO34063.1 - 2.2e-11 44.0 50.2 0.89 10.2 0.1 14.7 16 0 0 16 16 15 4 Sel1 repeat TPR_9 PF13371.1 ETO34063.1 - 3.4e-11 42.8 0.0 0.0034 17.2 0.0 6.8 6 2 1 7 7 7 2 Tetratricopeptide repeat PPR PF01535.15 ETO34063.1 - 8.8e-09 34.7 42.4 0.19 11.7 0.2 12.1 14 0 0 14 14 12 4 PPR repeat RPN7 PF10602.4 ETO34063.1 - 5.9e-08 32.2 40.7 0.0053 16.1 0.4 8.9 1 1 8 10 10 10 3 26S proteasome subunit RPN7 Ten1_2 PF15490.1 ETO34063.1 - 1.8e-06 27.5 0.1 38 3.8 0.0 8.3 1 1 5 10 10 10 0 Telomere-capping, CST complex subunit Fis1_TPR_C PF14853.1 ETO34063.1 - 0.0073 16.1 60.0 1.5 8.7 0.1 12.3 13 0 0 13 13 13 3 Fis1 C-terminal tetratricopeptide repeat KH_4 PF13083.1 ETO34063.1 - 0.021 14.4 4.0 6.3 6.5 0.0 5.3 3 3 3 6 6 6 0 KH domain Mob_Pre PF01076.14 ETO34063.1 - 0.11 12.1 31.6 0.14 11.7 0.8 6.8 1 1 6 8 8 8 0 Plasmid recombination enzyme TPR_21 PF09976.4 ETO34063.1 - 2.1 8.2 8.7 53 3.7 0.0 4.8 6 0 0 6 6 5 0 Tetratricopeptide repeat Hydantoinase_B PF02538.9 ETO34064.1 - 8.5e-20 70.4 0.1 9.7e-20 70.2 0.1 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase DUF2207 PF09972.4 ETO34064.1 - 1.6 7.2 5.2 1.9 6.9 3.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Hydantoinase_B PF02538.9 ETO34065.1 - 3.4e-115 385.2 0.0 4.2e-115 384.9 0.0 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase DUF496 PF04363.7 ETO34065.1 - 0.05 13.4 0.3 0.13 12.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF496) Peptidase_M91 PF14891.1 ETO34065.1 - 0.075 13.0 0.1 0.1 12.6 0.1 1.1 1 0 0 1 1 1 0 Effector protein WD40 PF00400.27 ETO34066.1 - 1.6e-09 37.3 0.5 1.6e-09 37.3 0.4 1.9 3 0 0 3 3 3 1 WD domain, G-beta repeat NTNH_C PF08470.5 ETO34066.1 - 0.012 15.2 0.3 0.014 15.0 0.2 1.2 1 0 0 1 1 1 0 Nontoxic nonhaemagglutinin C-terminal DAGK_acc PF00609.14 ETO34067.1 - 1.9e-35 122.3 0.0 5.3e-35 120.9 0.0 1.8 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 ETO34067.1 - 3.2e-16 58.9 0.0 6.9e-16 57.8 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Pox_G5 PF04599.7 ETO34068.1 - 0.094 11.3 2.5 0.099 11.3 1.7 1.1 1 0 0 1 1 1 0 Poxvirus G5 protein FadA PF09403.5 ETO34068.1 - 0.5 10.3 11.2 0.57 10.2 7.8 1.1 1 0 0 1 1 1 0 Adhesion protein FadA RR_TM4-6 PF06459.7 ETO34068.1 - 2.1 8.1 11.7 2.3 8.0 8.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CotH PF08757.6 ETO34068.1 - 2.1 7.5 7.8 2.1 7.4 5.4 1.0 1 0 0 1 1 1 0 CotH protein Sec62 PF03839.11 ETO34068.1 - 2.8 7.2 12.3 2.9 7.2 8.5 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 RP-C_C PF11800.3 ETO34068.1 - 6.1 6.4 8.3 6.3 6.4 5.7 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region Spore_coat_CotO PF14153.1 ETO34068.1 - 8.5 5.7 15.9 10 5.5 11.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF1510 PF07423.6 ETO34068.1 - 8.5 5.6 17.2 9.5 5.5 11.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RRS1 PF04939.7 ETO34069.1 - 7.6e-28 97.0 3.2 8.6e-28 96.8 2.2 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) PLD_C PF12357.3 ETO34069.1 - 0.034 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Phospholipase D C terminal LAGLIDADG_1 PF00961.14 ETO34070.1 - 3.3 8.3 10.4 2.9 8.5 1.4 2.2 1 1 1 2 2 2 0 LAGLIDADG endonuclease Kei1 PF08552.6 ETO34071.1 - 0.12 12.0 2.3 0.16 11.5 1.6 1.4 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Ribosomal_S2 PF00318.15 ETO34074.1 - 1.7 7.8 8.0 2.4 7.3 5.6 1.4 1 1 0 1 1 1 0 Ribosomal protein S2 WBS_methylT PF12589.3 ETO34075.1 - 0.46 10.9 0.1 0.46 10.9 0.1 2.6 3 0 0 3 3 3 0 Methyltransferase involved in Williams-Beuren syndrome DNA_pol_A PF00476.15 ETO34076.1 - 1.5e-50 171.9 0.9 7.8e-31 107.0 0.0 3.0 2 1 0 2 2 2 2 DNA polymerase family A LdpA_C PF12617.3 ETO34076.1 - 0.02 14.1 0.0 1.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Iron-Sulfur binding protein C terminal Lipase_GDSL_2 PF13472.1 ETO34077.1 - 0.001 19.2 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 ETO34077.1 - 0.0065 16.3 1.8 0.011 15.5 0.6 1.9 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase Pox_mRNA-cap PF03341.8 ETO34077.1 - 0.027 13.5 1.3 0.04 12.9 0.1 1.7 2 0 0 2 2 2 0 Poxvirus mRNA capping enzyme, small subunit Ins_allergen_rp PF06757.8 ETO34077.1 - 0.036 13.5 0.2 0.15 11.5 0.0 1.9 2 0 0 2 2 2 0 Insect allergen related repeat, nitrile-specifier detoxification Pkinase PF00069.20 ETO34078.1 - 1.1e-79 267.2 0.0 1.9e-79 266.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO34078.1 - 1.6e-39 135.5 0.0 2.5e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETO34078.1 - 1.6e-05 24.7 0.1 0.00059 19.6 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 ETO34078.1 - 0.00023 20.3 0.3 0.00058 18.9 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETO34078.1 - 0.0067 15.4 0.1 0.038 12.9 0.0 2.3 2 1 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.4 ETO34078.1 - 0.0071 15.7 0.2 0.015 14.6 0.1 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Mucin PF01456.12 ETO34078.1 - 0.11 12.2 8.9 0.21 11.3 6.2 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein MARVEL PF01284.18 ETO34078.1 - 0.14 12.0 2.5 0.99 9.2 0.7 2.6 3 0 0 3 3 3 0 Membrane-associating domain HSP70 PF00012.15 ETO34080.1 - 1.4e-32 112.3 0.1 3.5e-32 111.1 0.1 1.5 1 1 0 1 1 1 1 Hsp70 protein Actin PF00022.14 ETO34080.1 - 0.00026 19.5 0.0 0.00038 18.9 0.0 1.2 1 0 0 1 1 1 1 Actin BcrAD_BadFG PF01869.15 ETO34080.1 - 0.033 13.4 0.0 0.048 12.9 0.0 1.2 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family MreB_Mbl PF06723.8 ETO34080.1 - 0.05 12.1 0.1 0.094 11.2 0.1 1.4 1 1 0 1 1 1 0 MreB/Mbl protein UPF0075 PF03702.9 ETO34080.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0075) DUF1043 PF06295.7 ETO34081.1 - 0.052 13.1 4.6 0.42 10.2 2.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) RNR_inhib PF08591.5 ETO34082.1 - 4.4 8.2 7.5 2.5 9.0 1.9 2.6 2 1 0 2 2 2 0 Ribonucleotide reductase inhibitor Acyl-CoA_dh_1 PF00441.19 ETO34083.1 - 2.2e-12 47.3 1.1 2.6e-12 47.0 0.7 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ALS_ss_C PF10369.4 ETO34083.1 - 0.045 13.4 0.1 1.8 8.3 0.0 2.2 1 1 1 2 2 2 0 Small subunit of acetolactate synthase Tubulin PF00091.20 ETO34084.1 - 1.3e-58 198.3 0.1 7.2e-58 195.9 0.0 2.2 2 1 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO34084.1 - 3.8e-29 101.2 0.1 6.1e-29 100.6 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.1 ETO34084.1 - 0.066 12.1 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Acyl-CoA_dh_1 PF00441.19 ETO34085.1 - 1.1e-10 41.7 0.0 1.7e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SMC_N PF02463.14 ETO34086.1 - 3.7e-28 98.2 86.2 7.7e-27 93.9 59.7 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 ETO34086.1 - 3.2e-27 94.8 0.0 3.2e-27 94.8 0.0 2.9 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 ETO34086.1 - 5e-13 49.6 8.4 7.7e-09 35.9 0.1 5.1 4 2 1 5 5 5 2 AAA domain AAA_29 PF13555.1 ETO34086.1 - 1.3e-05 24.6 0.0 3.4e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 ETO34086.1 - 2.8e-05 23.4 17.8 0.23 10.5 0.2 4.3 4 0 0 4 4 4 3 Reovirus sigma C capsid protein SbcCD_C PF13558.1 ETO34086.1 - 8.8e-05 22.3 0.0 0.00032 20.5 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit FliJ PF02050.11 ETO34086.1 - 0.0032 17.5 21.1 0.0032 17.5 14.6 9.8 4 3 4 9 9 9 2 Flagellar FliJ protein ABC_tran PF00005.22 ETO34086.1 - 0.21 11.9 0.0 0.21 11.9 0.0 6.4 3 2 0 3 3 3 0 ABC transporter TAP42 PF04177.7 ETO34087.1 - 0.17 10.7 11.9 0.087 11.7 3.7 2.1 2 0 0 2 2 2 0 TAP42-like family HD-ZIP_N PF04618.7 ETO34087.1 - 0.52 10.8 2.7 1.3 9.6 0.4 2.1 2 0 0 2 2 2 0 HD-ZIP protein N terminus Unstab_antitox PF09720.5 ETO34089.1 - 0.042 13.5 0.6 1.3 8.7 0.0 2.7 2 1 0 2 2 2 0 Putative addiction module component DUF1690 PF07956.6 ETO34089.1 - 0.045 13.7 3.6 0.061 13.3 2.5 1.1 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Tubulin_C PF03953.12 ETO34090.1 - 4.2e-10 39.7 0.0 2.8e-06 27.3 0.0 2.2 1 1 1 2 2 2 2 Tubulin C-terminal domain Lactonase PF10282.4 ETO34091.1 - 3.1e-12 46.2 0.0 3.4e-12 46.1 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DUF1295 PF06966.7 ETO34092.1 - 3.1e-31 108.4 9.8 3.1e-31 108.4 6.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) ICMT PF04140.9 ETO34092.1 - 0.00019 21.5 0.7 0.00095 19.3 0.1 2.5 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 ETO34092.1 - 0.006 16.6 1.4 0.006 16.6 0.9 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase R3H-assoc PF13902.1 ETO34094.1 - 0.027 14.4 0.1 0.058 13.3 0.1 1.5 1 0 0 1 1 1 0 R3H-associated N-terminal domain RNA_pol_Rpb8 PF03870.10 ETO34095.1 - 4.7e-41 140.2 0.5 5.9e-41 139.8 0.3 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb8 Amidase PF01425.16 ETO34096.1 - 1e-32 113.5 0.0 2.5e-32 112.3 0.0 1.5 1 1 0 1 1 1 1 Amidase Kelch_4 PF13418.1 ETO34097.1 - 0.0013 18.4 0.9 3.8 7.3 0.1 3.6 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO34097.1 - 0.035 14.2 6.6 1.3 9.2 0.3 4.1 3 1 1 4 4 4 0 Kelch motif Kelch_2 PF07646.10 ETO34097.1 - 0.036 13.8 2.2 7.4 6.5 0.1 3.8 4 0 0 4 4 4 0 Kelch motif zf-C2H2 PF00096.21 ETO34098.1 - 4.9e-11 42.2 28.0 0.0001 22.4 1.0 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETO34098.1 - 7.9e-10 38.3 27.3 0.0019 18.3 0.6 3.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETO34098.1 - 2e-06 27.7 27.5 0.0051 17.0 3.3 4.6 4 0 0 4 4 4 3 Zinc-finger double domain zf-met PF12874.2 ETO34098.1 - 3.3e-06 27.1 17.0 0.049 13.8 0.8 3.6 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 ETO34098.1 - 0.0019 18.2 1.1 0.0019 18.2 0.7 3.6 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 ETO34098.1 - 0.062 13.4 22.0 0.16 12.0 1.3 3.6 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.5 ETO34098.1 - 2.1 8.3 15.5 4 7.4 0.7 3.5 3 0 0 3 3 3 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 ETO34098.1 - 3.6 7.4 12.9 5.9 6.7 3.1 2.9 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-trcl PF13451.1 ETO34098.1 - 5.6 6.6 12.8 0.66 9.6 0.5 3.2 3 0 0 3 3 3 0 Probable zinc-binding domain G0-G1_switch_2 PF15103.1 ETO34099.1 - 0.0018 18.4 0.8 0.003 17.7 0.1 1.6 2 0 0 2 2 2 1 G0/G1 switch protein 2 Adeno_E3A PF05248.7 ETO34099.1 - 0.03 14.3 0.2 0.071 13.1 0.1 1.6 1 0 0 1 1 1 0 Adenovirus E3A Med12-LCEWAV PF12145.3 ETO34099.1 - 2 6.8 7.3 0.23 9.9 1.8 1.6 2 0 0 2 2 2 0 Eukaryotic Mediator 12 subunit domain DUF1033 PF06279.6 ETO34100.1 - 0.075 12.8 4.2 0.2 11.5 2.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) Uds1 PF15456.1 ETO34100.1 - 0.19 11.7 12.0 0.083 12.8 2.3 2.1 2 0 0 2 2 2 0 Up-regulated During Septation Allexi_40kDa PF05549.6 ETO34100.1 - 0.22 10.7 4.7 0.17 11.1 1.1 1.9 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF342 PF03961.8 ETO34100.1 - 0.26 9.6 6.0 0.2 10.0 3.3 1.3 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF3452 PF11934.3 ETO34100.1 - 0.27 10.5 3.3 0.94 8.8 1.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) EAP30 PF04157.11 ETO34100.1 - 0.36 9.9 4.7 6.1 5.9 1.8 2.2 2 0 0 2 2 2 0 EAP30/Vps36 family DUF4407 PF14362.1 ETO34100.1 - 2.2 7.1 6.5 0.33 9.8 1.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) XhlA PF10779.4 ETO34100.1 - 6.4 6.7 9.9 1.6 8.7 3.7 2.1 2 0 0 2 2 2 0 Haemolysin XhlA Macro PF01661.16 ETO34101.1 - 1.7e-28 98.8 0.4 2.8e-28 98.1 0.3 1.4 1 0 0 1 1 1 1 Macro domain 7TM_GPCR_Srd PF10317.4 ETO34102.1 - 0.024 13.6 0.9 0.047 12.6 0.7 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd DUF1746 PF08508.5 ETO34102.1 - 0.17 11.8 2.7 2.4 8.1 0.2 2.3 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1746) DUF2039 PF10217.4 ETO34102.1 - 0.65 10.0 9.5 0.26 11.3 3.9 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) DUF4264 PF14084.1 ETO34103.1 - 0.0088 15.3 0.5 0.031 13.6 0.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF4264) Reo_sigmaC PF04582.7 ETO34104.1 - 0.00083 18.6 9.4 0.0013 18.0 1.1 2.3 1 1 1 2 2 2 2 Reovirus sigma C capsid protein Spc7 PF08317.6 ETO34104.1 - 0.0025 16.5 28.5 0.0025 16.5 19.8 2.1 1 1 1 2 2 2 1 Spc7 kinetochore protein BRE1 PF08647.6 ETO34104.1 - 0.0075 16.2 11.3 0.0075 16.2 7.8 3.1 1 1 2 3 3 2 1 BRE1 E3 ubiquitin ligase DUF4201 PF13870.1 ETO34104.1 - 0.008 15.6 31.2 0.0087 15.5 20.4 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) Transposase_22 PF02994.9 ETO34104.1 - 0.015 13.8 27.2 0.013 14.0 17.8 1.6 1 1 0 1 1 1 0 L1 transposable element Macoilin PF09726.4 ETO34104.1 - 0.023 12.9 25.0 0.026 12.8 17.3 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF869 PF05911.6 ETO34104.1 - 0.053 11.7 32.5 0.066 11.4 22.6 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) TMF_TATA_bd PF12325.3 ETO34104.1 - 0.11 12.2 27.5 0.48 10.1 9.7 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.7 ETO34104.1 - 0.24 11.2 18.5 0.54 10.0 5.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ERM PF00769.14 ETO34104.1 - 1.1 8.7 28.7 0.71 9.3 18.0 1.9 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Fib_alpha PF08702.5 ETO34104.1 - 2.7 8.0 40.6 1.7 8.7 4.5 3.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family IncA PF04156.9 ETO34104.1 - 3.5 7.1 32.5 2.7 7.5 16.3 2.2 1 1 1 2 2 2 0 IncA protein TMF_DNA_bd PF12329.3 ETO34104.1 - 4 7.3 41.2 0.24 11.2 11.0 4.0 2 1 1 4 4 3 0 TATA element modulatory factor 1 DNA binding Phage_GP20 PF06810.6 ETO34104.1 - 4.1 6.8 39.5 5.3 6.4 18.8 3.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF641 PF04859.7 ETO34104.1 - 4.4 7.0 24.5 0.17 11.6 2.1 3.3 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) DUF2961 PF11175.3 ETO34105.1 - 5.7e-19 68.3 0.1 1.8e-18 66.7 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2961) TPR_11 PF13414.1 ETO34106.1 - 3.2e-06 26.6 0.9 5.2e-06 26.0 0.6 1.3 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 ETO34106.1 - 0.00013 21.6 0.9 0.031 14.1 0.7 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO34106.1 - 0.00029 20.8 0.4 0.022 14.9 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO34106.1 - 0.00039 20.3 1.1 0.0011 18.8 0.6 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO34106.1 - 0.00064 20.3 0.0 0.0013 19.3 0.0 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO34106.1 - 0.024 14.2 0.2 0.083 12.5 0.4 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETO34106.1 - 0.03 14.6 0.1 0.21 11.9 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat Peptidase_C2 PF00648.16 ETO34107.1 - 6.2e-28 97.6 0.0 7.7e-28 97.3 0.0 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease PsbI PF02532.9 ETO34107.1 - 0.18 11.4 8.9 0.045 13.3 3.7 1.8 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) EMP24_GP25L PF01105.19 ETO34108.1 - 3.5e-15 56.1 5.7 3.5e-15 56.1 3.9 1.6 1 1 1 2 2 2 1 emp24/gp25L/p24 family/GOLD Herpes_US9 PF06072.6 ETO34108.1 - 0.84 9.5 4.3 0.41 10.5 0.4 2.0 1 1 1 2 2 2 0 Alphaherpesvirus tegument protein US9 FYVE PF01363.16 ETO34109.1 - 0.38 10.6 7.1 2.5 8.0 2.4 2.6 2 0 0 2 2 2 0 FYVE zinc finger DUF3825 PF12873.2 ETO34110.1 - 0.005 16.0 1.0 6 5.9 0.0 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF3825) UvsY PF11056.3 ETO34110.1 - 0.085 12.9 0.7 1.3 9.1 0.1 2.7 2 0 0 2 2 2 0 Recombination, repair and ssDNA binding protein UvsY Sulfatase PF00884.18 ETO34111.1 - 6e-18 65.0 0.0 2.6e-17 62.9 0.0 1.8 2 0 0 2 2 2 1 Sulfatase Sulfatase_C PF14707.1 ETO34111.1 - 7.7e-18 65.0 1.0 7.7e-18 65.0 0.7 1.8 2 0 0 2 2 2 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 ETO34111.1 - 1.5e-05 24.5 0.0 2.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.7 ETO34111.1 - 0.033 13.0 0.0 0.049 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DSPc PF00782.15 ETO34112.1 - 3.5e-25 88.1 0.3 4.7e-25 87.7 0.2 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain zf-Di19 PF05605.7 ETO34112.1 - 7.8e-06 25.9 1.0 1.9e-05 24.7 0.7 1.7 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Y_phosphatase PF00102.22 ETO34112.1 - 0.00085 18.7 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 ETO34112.1 - 0.0019 17.1 0.1 0.0024 16.8 0.1 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase2 PF03162.8 ETO34112.1 - 0.0069 15.7 0.5 0.016 14.5 0.2 1.7 1 1 1 2 2 2 1 Tyrosine phosphatase family CDKN3 PF05706.7 ETO34112.1 - 0.018 14.5 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.1 ETO34112.1 - 0.021 15.0 0.0 0.035 14.3 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF2733 PF10813.3 ETO34112.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2733) zf-C2H2_4 PF13894.1 ETO34112.1 - 0.33 11.3 4.4 0.14 12.5 0.9 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger Tantalus PF15386.1 ETO34113.1 - 0.11 12.3 0.2 0.61 9.8 0.0 2.1 2 0 0 2 2 2 0 Drosophila Tantalus-like PPR PF01535.15 ETO34116.1 - 1.1e-15 56.4 6.0 0.00029 20.5 0.1 4.9 4 0 0 4 4 4 4 PPR repeat PPR_2 PF13041.1 ETO34116.1 - 2e-08 34.0 12.7 0.0099 15.8 0.6 4.5 3 1 2 5 5 5 4 PPR repeat family PPR_1 PF12854.2 ETO34116.1 - 1.2e-07 31.0 2.6 0.031 13.7 0.0 3.6 3 0 0 3 3 3 3 PPR repeat PPR_3 PF13812.1 ETO34116.1 - 3.5e-06 26.8 0.0 1.7 9.1 0.0 4.8 5 0 0 5 5 5 2 Pentatricopeptide repeat domain ATP13 PF12921.2 ETO34116.1 - 0.009 15.3 0.1 0.027 13.8 0.1 1.8 1 0 0 1 1 1 1 Mitochondrial ATPase expression Peptidase_S9_N PF02897.10 ETO34117.1 - 9.6e-15 54.0 0.0 8.3e-08 31.2 0.0 2.0 2 0 0 2 2 2 2 Prolyl oligopeptidase, N-terminal beta-propeller domain Baculo_LEF-2 PF03041.9 ETO34118.1 - 0.021 14.4 0.6 0.021 14.4 0.4 1.6 2 0 0 2 2 2 0 lef-2 WD40 PF00400.27 ETO34119.1 - 1.1e-08 34.5 0.3 1.1e-08 34.5 0.2 2.1 2 0 0 2 2 2 1 WD domain, G-beta repeat WD40 PF00400.27 ETO34120.1 - 1e-10 41.0 5.4 6.5e-08 32.1 2.2 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat zf-TRAF PF02176.13 ETO34120.1 - 0.00024 21.3 6.6 0.00024 21.3 4.6 2.4 2 0 0 2 2 2 1 TRAF-type zinc finger TrbI_Ftype PF09677.5 ETO34120.1 - 0.024 14.4 4.8 0.47 10.2 1.7 2.9 3 0 0 3 3 3 0 Type-F conjugative transfer system protein (TrbI_Ftype) ArsC PF03960.10 ETO34123.1 - 1.9 8.5 5.6 3.7 7.6 0.2 2.7 2 0 0 2 2 2 0 ArsC family ZZ PF00569.12 ETO34124.1 - 8.8e-11 41.1 3.6 2e-10 40.0 2.5 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type UBA PF00627.26 ETO34124.1 - 0.018 14.8 0.0 0.049 13.4 0.0 1.8 1 0 0 1 1 1 0 UBA/TS-N domain DUF4228 PF14009.1 ETO34125.1 - 0.013 15.6 1.9 0.021 14.9 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4228) Syntaxin-18_N PF10496.4 ETO34125.1 - 1.6 8.6 7.2 0.44 10.4 0.1 2.7 2 1 1 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus RhoGAP PF00620.22 ETO34126.1 - 2.4e-18 66.1 0.4 5.6e-18 65.0 0.3 1.6 1 0 0 1 1 1 1 RhoGAP domain Arf PF00025.16 ETO34128.1 - 2.4e-24 85.5 0.7 3.7e-12 45.8 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family ATP11 PF06644.6 ETO34128.1 - 0.092 12.2 0.6 0.25 10.8 0.0 1.9 1 1 2 3 3 3 0 ATP11 protein DUF3166 PF11365.3 ETO34129.1 - 0.11 12.9 6.2 0.19 12.1 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) DUF4587 PF15248.1 ETO34130.1 - 0.41 11.2 2.2 0.64 10.6 1.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4587) Orthopox_A36R PF05950.6 ETO34130.1 - 2.8 7.8 7.4 3.1 7.7 5.2 1.1 1 0 0 1 1 1 0 Orthopoxvirus A36R protein DUF724 PF05266.9 ETO34130.1 - 3.4 7.2 11.2 3.7 7.1 7.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4512 PF14975.1 ETO34130.1 - 4.6 8.1 6.5 6 7.7 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Vfa1 PF08432.5 ETO34130.1 - 6.4 6.7 17.8 6.5 6.7 12.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Neisseria_TspB PF05616.8 ETO34131.1 - 0.16 10.3 8.7 0.23 9.7 6.0 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Kinesin PF00225.18 ETO34132.1 - 2.6e-92 309.1 0.2 2.6e-92 309.1 0.1 2.7 2 2 1 3 3 3 1 Kinesin motor domain DEAD PF00270.24 ETO34132.1 - 0.032 13.7 2.2 4.1 6.8 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase Reo_sigmaC PF04582.7 ETO34132.1 - 0.27 10.3 6.1 0.52 9.4 4.2 1.5 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Herpes_UL92 PF03048.9 ETO34133.1 - 0.00073 19.1 4.6 0.00098 18.7 3.2 1.2 1 0 0 1 1 1 1 UL92 family KaiC PF06745.8 ETO34133.1 - 0.0048 16.0 6.2 0.006 15.7 4.3 1.2 1 0 0 1 1 1 1 KaiC Mnd1 PF03962.10 ETO34133.1 - 0.01 15.4 9.3 0.012 15.2 6.4 1.3 1 0 0 1 1 1 0 Mnd1 family GBP_C PF02841.9 ETO34133.1 - 0.012 14.7 15.1 0.016 14.3 10.5 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF3373 PF11853.3 ETO34133.1 - 0.012 14.1 5.8 0.014 13.9 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Seryl_tRNA_N PF02403.17 ETO34133.1 - 0.022 14.7 19.0 0.027 14.4 12.8 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 ETO34133.1 - 0.025 13.6 10.7 0.031 13.3 7.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2785 PF10978.3 ETO34133.1 - 0.029 13.8 1.2 0.039 13.4 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2785) DUF883 PF05957.8 ETO34133.1 - 0.039 14.3 2.9 0.084 13.2 1.9 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF4613 PF15390.1 ETO34133.1 - 0.058 11.5 7.5 0.082 11.0 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) MMPL PF03176.10 ETO34133.1 - 0.062 11.9 0.7 0.1 11.2 0.5 1.3 1 0 0 1 1 1 0 MMPL family V_ATPase_I PF01496.14 ETO34133.1 - 0.076 10.8 9.8 0.083 10.7 6.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 ETO34133.1 - 0.1 11.5 10.1 0.11 11.4 7.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Toprim_2 PF13155.1 ETO34133.1 - 0.1 12.8 2.5 0.17 12.2 1.0 1.8 1 1 1 2 2 2 0 Toprim-like IncA PF04156.9 ETO34133.1 - 0.12 11.9 10.7 0.15 11.6 7.4 1.2 1 0 0 1 1 1 0 IncA protein LUC7 PF03194.10 ETO34133.1 - 0.14 11.6 8.6 0.16 11.5 6.0 1.2 1 0 0 1 1 1 0 LUC7 N_terminus ComX PF05952.7 ETO34133.1 - 0.16 11.4 1.1 0.34 10.4 0.0 2.1 2 0 0 2 2 2 0 Bacillus competence pheromone ComX MitMem_reg PF13012.1 ETO34133.1 - 0.2 11.7 10.9 0.37 10.8 7.0 1.9 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function ATG16 PF08614.6 ETO34133.1 - 0.23 11.2 11.6 0.28 10.9 8.0 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) FlgN PF05130.7 ETO34133.1 - 0.24 11.6 10.1 0.87 9.8 2.6 2.5 1 1 0 2 2 2 0 FlgN protein DUF148 PF02520.12 ETO34133.1 - 0.26 11.0 12.9 0.33 10.7 8.5 1.6 1 1 0 1 1 1 0 Domain of unknown function DUF148 Fib_alpha PF08702.5 ETO34133.1 - 0.34 11.0 14.9 0.28 11.2 9.3 1.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF2935 PF11155.3 ETO34133.1 - 0.34 11.0 8.8 0.55 10.3 6.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) DUF262 PF03235.9 ETO34133.1 - 0.36 10.7 4.2 0.43 10.5 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 Mem_trans PF03547.13 ETO34133.1 - 0.43 8.8 4.6 0.51 8.5 3.2 1.1 1 0 0 1 1 1 0 Membrane transport protein RNA_pol_Rpb1_5 PF04998.12 ETO34133.1 - 0.48 9.6 7.7 0.75 8.9 5.3 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 AAA_11 PF13086.1 ETO34133.1 - 0.55 9.7 5.9 0.69 9.4 4.1 1.2 1 0 0 1 1 1 0 AAA domain DUF1515 PF07439.6 ETO34133.1 - 0.6 9.9 5.5 0.76 9.6 3.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) PRCC PF10253.4 ETO34133.1 - 0.62 10.7 7.2 0.79 10.3 5.0 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting NAD_binding_1 PF00175.16 ETO34133.1 - 0.65 10.5 3.1 1.3 9.5 2.2 1.5 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain Toprim PF01751.17 ETO34133.1 - 0.97 9.4 7.4 2.4 8.1 5.1 1.9 1 1 0 1 1 1 0 Toprim domain DUF4194 PF13835.1 ETO34133.1 - 1.2 8.5 6.2 1.4 8.3 3.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4194) Prominin PF05478.6 ETO34133.1 - 1.5 6.2 9.4 1.8 6.0 5.9 1.4 1 1 0 1 1 1 0 Prominin CDC37_N PF03234.9 ETO34133.1 - 2 8.7 14.6 2.4 8.4 9.8 1.3 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Gp-FAR-1 PF05823.7 ETO34133.1 - 2.5 8.0 17.7 10 6.0 12.3 1.8 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Glu_syn_central PF04898.9 ETO34133.1 - 3 7.0 7.9 4.6 6.4 5.5 1.4 1 1 0 1 1 1 0 Glutamate synthase central domain YtxH PF12732.2 ETO34133.1 - 3.1 8.2 9.9 8.5 6.8 6.8 1.7 1 0 0 1 1 1 0 YtxH-like protein DUF2317 PF10079.4 ETO34133.1 - 4 5.9 13.1 6 5.3 8.8 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) DUF4047 PF13256.1 ETO34133.1 - 4.3 7.3 16.0 8.6 6.3 10.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) VSG_B PF13206.1 ETO34133.1 - 5.8 5.9 8.5 6.9 5.6 5.9 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain MRP-L28 PF09812.4 ETO34133.1 - 6 6.6 13.6 36 4.1 2.9 2.0 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L28 ACCA PF03255.9 ETO34133.1 - 6.2 6.3 11.6 9.2 5.8 6.7 2.2 1 1 2 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF724 PF05266.9 ETO34133.1 - 6.7 6.2 17.0 9.8 5.7 11.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) COG2 PF06148.6 ETO34133.1 - 6.9 6.5 11.8 10 6.0 5.9 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2229 PF09989.4 ETO34133.1 - 7 6.0 10.0 11 5.3 6.6 1.6 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Vpu PF00558.14 ETO34133.1 - 8.6 5.9 8.9 29 4.2 6.2 2.0 1 1 0 1 1 1 0 Vpu protein AAA_23 PF13476.1 ETO34133.1 - 10 6.4 16.3 15 5.7 11.3 1.3 1 0 0 1 1 1 0 AAA domain Acetyltransf_1 PF00583.19 ETO34134.1 - 4.3e-05 23.4 0.0 7.3e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 ETO34134.1 - 0.013 15.3 0.0 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 ETO34134.1 - 0.014 15.4 0.1 0.029 14.5 0.1 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4380 PF14315.1 ETO34134.1 - 0.13 11.3 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4380) Folate_carrier PF01770.13 ETO34137.1 - 0.21 10.0 1.4 0.27 9.7 0.9 1.2 1 0 0 1 1 1 0 Reduced folate carrier Ribonuc_2-5A PF06479.7 ETO34137.1 - 1.6 8.5 6.0 0.7 9.7 2.4 1.5 2 0 0 2 2 2 0 Ribonuclease 2-5A Cyclin_N PF00134.18 ETO34138.1 - 3.7e-15 55.6 1.5 5.6e-14 51.8 1.0 2.0 1 1 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 ETO34138.1 - 0.0031 17.2 0.0 0.0056 16.4 0.0 1.3 1 0 0 1 1 1 1 Transcription factor TFIIB repeat NOD PF06816.8 ETO34138.1 - 0.037 13.1 0.0 0.074 12.1 0.0 1.5 1 0 0 1 1 1 0 NOTCH protein DUF2142 PF09913.4 ETO34140.1 - 2.1 6.9 13.9 3.4 6.2 9.7 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2142) UCH PF00443.24 ETO34143.1 - 9.3e-50 169.2 2.9 9.3e-50 169.2 2.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO34143.1 - 1.3e-15 57.6 12.7 1.3e-15 57.6 8.8 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 ETO34143.1 - 4.7e-08 32.3 0.5 1.8e-07 30.4 0.3 2.0 2 0 0 2 2 2 1 Ubiquitin family CDC45 PF02724.9 ETO34143.1 - 0.059 11.4 9.8 0.11 10.5 6.8 1.4 1 0 0 1 1 1 0 CDC45-like protein Salp15 PF12115.3 ETO34144.1 - 0.34 11.1 2.7 0.4 10.9 1.8 1.3 1 1 0 1 1 1 0 Salivary protein of 15kDa inhibits CD4+ T cell activation HrpB7 PF09486.5 ETO34147.1 - 0.39 10.6 3.4 3.2 7.6 0.5 2.4 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF2265 PF10023.4 ETO34147.1 - 0.74 8.8 4.4 0.16 11.0 1.0 1.4 2 0 0 2 2 2 0 Predicted aminopeptidase (DUF2265) DUF4201 PF13870.1 ETO34148.1 - 2.4e-19 69.4 31.0 2.4e-19 69.4 21.5 3.1 2 2 0 2 2 2 1 Domain of unknown function (DUF4201) DOG1 PF14144.1 ETO34148.1 - 0.054 13.5 0.4 0.36 10.9 0.3 2.5 1 0 0 1 1 1 0 Seed dormancy control DUF3699 PF12480.3 ETO34148.1 - 0.074 12.6 1.4 2.1 8.0 0.3 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3699) PAD PF03068.10 ETO34148.1 - 0.83 8.0 5.3 0.49 8.7 0.2 2.1 1 1 1 2 2 2 0 Protein-arginine deiminase (PAD) NTS_2 PF15448.1 ETO34148.1 - 7.7 6.8 7.3 1.9 8.8 0.1 2.9 3 0 0 3 3 3 0 N-terminal segments of P. falciparum erythrocyte membrane protein DUF3417 PF11897.3 ETO34149.1 - 0.012 15.5 0.0 0.031 14.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) TfoX_N PF04993.8 ETO34150.1 - 0.0043 16.8 0.5 0.009 15.8 0.1 1.6 1 1 0 2 2 2 1 TfoX N-terminal domain Prok-TraM PF09228.5 ETO34150.1 - 0.39 10.8 2.7 0.57 10.3 0.1 2.0 1 1 1 2 2 2 0 Prokaryotic Transcriptional repressor TraM HBS1_N PF08938.5 ETO34152.1 - 0.042 13.9 0.4 0.052 13.6 0.2 1.3 1 1 0 1 1 1 0 HBS1 N-terminus B5 PF03484.10 ETO34152.1 - 0.043 13.6 0.1 0.072 12.9 0.1 1.4 1 1 0 1 1 1 0 tRNA synthetase B5 domain DUF4580 PF15162.1 ETO34152.1 - 0.055 12.8 0.4 0.08 12.3 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4580) UPF0180 PF03698.8 ETO34152.1 - 0.057 13.2 0.4 0.096 12.5 0.3 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0180) FAM92 PF06730.6 ETO34152.1 - 0.065 12.5 1.7 0.066 12.5 1.2 1.1 1 0 0 1 1 1 0 FAM92 protein DUF3855 PF12967.2 ETO34152.1 - 0.079 12.4 0.4 0.15 11.6 0.2 1.5 1 1 1 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3855) Thr_dehydrat_C PF00585.13 ETO34152.1 - 0.1 12.2 0.2 0.16 11.6 0.1 1.3 1 1 0 1 1 1 0 C-terminal regulatory domain of Threonine dehydratase DUF22 PF01629.11 ETO34152.1 - 0.11 12.0 0.3 0.14 11.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF22 TusA PF01206.12 ETO34152.1 - 0.11 12.1 0.2 0.18 11.4 0.1 1.5 1 1 0 1 1 1 0 Sulfurtransferase TusA Ribonuc_L-PSP PF01042.16 ETO34152.1 - 0.11 12.2 0.4 0.16 11.7 0.3 1.3 1 1 0 1 1 1 0 Endoribonuclease L-PSP DUF3482 PF11981.3 ETO34152.1 - 0.15 11.2 0.8 0.16 11.2 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Hexapep PF00132.19 ETO34153.1 - 0.00012 21.4 16.4 0.0022 17.4 1.6 4.2 2 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) IER PF05760.7 ETO34153.1 - 0.061 13.2 1.5 0.079 12.8 1.0 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) Hexapep_2 PF14602.1 ETO34153.1 - 0.19 11.3 12.0 0.25 10.9 1.1 2.8 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase YajC PF02699.10 ETO34153.1 - 0.23 11.1 1.8 57 3.4 0.0 3.6 3 0 0 3 3 3 0 Preprotein translocase subunit PHD PF00628.24 ETO34154.1 - 2.1e-09 36.9 10.5 3.9e-09 36.0 7.3 1.5 1 0 0 1 1 1 1 PHD-finger DEP PF00610.16 ETO34155.1 - 2.7e-17 62.2 1.7 2.7e-17 62.2 0.1 1.8 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) WD40 PF00400.27 ETO34156.1 - 1.8e-56 186.1 22.3 1e-10 41.0 0.3 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO34156.1 - 4.7e-10 38.2 2.6 0.45 8.5 0.2 5.4 2 2 3 5 5 5 5 Nucleoporin Nup120/160 SH3_2 PF07653.12 ETO34156.1 - 0.077 12.5 0.1 0.48 9.9 0.1 2.2 2 0 0 2 2 2 0 Variant SH3 domain OspD PF03207.8 ETO34157.1 - 0.024 13.8 0.2 0.039 13.1 0.2 1.3 1 0 0 1 1 1 0 Borrelia outer surface protein D (OspD) Phage_connect_1 PF05135.8 ETO34158.1 - 0.0067 16.5 1.1 0.017 15.2 0.1 2.1 2 1 1 3 3 3 1 Phage gp6-like head-tail connector protein DUF3015 PF11220.3 ETO34159.1 - 0.061 12.9 0.1 0.077 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) DUF2312 PF10073.4 ETO34160.1 - 0.02 14.2 0.1 0.04 13.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) RNHCP PF12647.2 ETO34161.1 - 0.046 13.5 0.1 2.6 7.9 0.1 2.1 2 0 0 2 2 2 0 RNHCP domain DUF1295 PF06966.7 ETO34162.1 - 6.9e-30 104.0 19.6 6.9e-30 104.0 13.6 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) ICMT PF04140.9 ETO34162.1 - 0.00066 19.8 2.6 0.00087 19.4 0.2 2.6 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 ETO34162.1 - 0.0027 17.7 2.1 0.0027 17.7 1.5 2.2 3 0 0 3 3 3 1 Phospholipid methyltransferase V_ATPase_I PF01496.14 ETO34163.1 - 6.2e-192 639.4 10.8 7e-192 639.2 7.5 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Zip PF02535.17 ETO34163.1 - 0.0022 17.0 1.1 0.0069 15.4 0.8 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter DUF4280 PF14107.1 ETO34164.1 - 0.11 12.7 0.1 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4280) TPR_2 PF07719.12 ETO34170.1 - 1.1e-05 24.9 1.6 2.1e-05 24.0 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO34170.1 - 2.7e-05 23.7 0.2 5.7e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 ETO34170.1 - 3e-05 23.4 0.3 6.7e-05 22.3 0.2 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO34170.1 - 0.005 17.3 1.0 0.012 16.1 0.0 2.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Mitofilin PF09731.4 ETO34170.1 - 0.0093 14.6 3.6 0.012 14.2 2.5 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein TPR_16 PF13432.1 ETO34170.1 - 0.035 14.7 0.2 0.13 12.9 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4510 PF14971.1 ETO34170.1 - 0.061 13.4 0.5 51 4.0 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4510) TPR_8 PF13181.1 ETO34170.1 - 0.11 12.3 0.1 0.11 12.3 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO34170.1 - 0.17 12.3 0.1 0.17 12.3 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Kinase-PPPase PF03618.9 ETO34171.1 - 0.0019 17.7 1.5 0.019 14.4 0.5 2.3 2 0 0 2 2 2 1 Kinase/pyrophosphorylase MCPsignal PF00015.16 ETO34171.1 - 0.13 11.8 0.2 0.23 10.9 0.2 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SpoIIAA-like PF11964.3 ETO34172.1 - 0.003 17.8 0.0 0.0087 16.3 0.0 1.8 1 0 0 1 1 1 1 SpoIIAA-like Myb_DNA-binding PF00249.26 ETO34172.1 - 0.014 15.4 0.1 0.031 14.3 0.1 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF2450 PF10475.4 ETO34172.1 - 0.098 11.5 4.2 0.065 12.1 1.3 1.7 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) ATP-synt_E PF05680.7 ETO34172.1 - 2.1 8.3 6.3 0.6 10.1 0.5 2.3 2 0 0 2 2 2 0 ATP synthase E chain SWIRM PF04433.12 ETO34173.1 - 0.0001 22.3 0.1 0.00024 21.1 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain Metalloenzyme PF01676.13 ETO34174.1 - 0.014 14.7 0.5 0.022 14.1 0.4 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily CRAL_TRIO PF00650.15 ETO34176.1 - 6.2e-10 38.7 1.8 3.1e-09 36.5 0.2 2.4 1 1 1 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 ETO34176.1 - 1.1 9.1 7.9 0.33 10.8 1.7 2.7 3 0 0 3 3 3 0 Divergent CRAL/TRIO domain XPC-binding PF09280.6 ETO34177.1 - 0.00058 19.2 22.0 0.019 14.3 4.5 2.5 2 0 0 2 2 2 2 XPC-binding domain ComX PF05952.7 ETO34177.1 - 0.17 11.4 3.6 1.5 8.3 0.3 2.4 2 0 0 2 2 2 0 Bacillus competence pheromone ComX SOG2 PF10428.4 ETO34177.1 - 0.19 10.3 38.1 0.026 13.2 23.0 1.8 2 0 0 2 2 2 0 RAM signalling pathway protein DUF1675 PF07897.6 ETO34177.1 - 4.9 6.9 23.9 8.5 6.1 16.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Macoilin PF09726.4 ETO34177.1 - 7.2 4.7 30.8 11 4.1 21.4 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF883 PF05957.8 ETO34178.1 - 2.5 8.5 6.8 0.84 10.0 1.8 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Kinesin PF00225.18 ETO34179.1 - 2e-37 128.6 0.1 2.4e-37 128.4 0.1 1.1 1 0 0 1 1 1 1 Kinesin motor domain HSP70 PF00012.15 ETO34179.1 - 0.08 10.8 0.0 0.12 10.2 0.0 1.3 1 0 0 1 1 1 0 Hsp70 protein Lung_7-TM_R PF06814.8 ETO34180.1 - 1.6e-32 112.6 16.6 2.4e-32 112.0 11.5 1.3 1 1 0 1 1 1 1 Lung seven transmembrane receptor Osteopontin PF00865.13 ETO34180.1 - 0.86 8.7 19.5 1.2 8.3 13.5 1.1 1 0 0 1 1 1 0 Osteopontin DUF3792 PF12670.2 ETO34180.1 - 1.1 9.0 7.4 0.37 10.6 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) DUF1049 PF06305.6 ETO34180.1 - 2 7.9 6.3 0.88 9.0 1.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1049) DUF2208 PF09973.4 ETO34180.1 - 3.7 6.7 8.2 0.73 9.0 1.7 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) DUF3112 PF11309.3 ETO34180.1 - 6.3 6.5 10.5 1.5 8.5 1.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3112) Lung_7-TM_R PF06814.8 ETO34181.1 - 5e-12 45.3 0.9 6.1e-12 45.0 0.6 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor Herpes_US9 PF06072.6 ETO34181.1 - 0.12 12.2 0.9 0.78 9.6 0.0 2.1 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 AAA_33 PF13671.1 ETO34182.1 - 9e-06 25.6 0.1 2.1e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETO34182.1 - 0.00011 22.4 1.9 0.00037 20.8 1.3 2.0 1 0 0 1 1 1 1 AAA domain DUF3530 PF12048.3 ETO34182.1 - 0.012 14.6 1.3 0.02 13.8 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) OpgC_C PF10129.4 ETO34182.1 - 0.016 13.9 1.1 0.021 13.4 0.8 1.1 1 0 0 1 1 1 0 OpgC protein NACHT PF05729.7 ETO34182.1 - 0.049 13.3 0.1 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 ETO34182.1 - 0.066 13.4 0.2 0.25 11.5 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 ETO34182.1 - 0.11 13.2 3.7 0.21 12.4 1.9 2.3 2 1 0 2 2 2 0 AAA domain Tetraspannin PF00335.15 ETO34182.1 - 0.73 9.0 5.4 1.6 7.9 3.8 1.5 1 0 0 1 1 1 0 Tetraspanin family DUF1510 PF07423.6 ETO34182.1 - 8.9 5.6 19.8 2.1 7.6 11.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) WD40 PF00400.27 ETO34185.1 - 7.2e-83 269.7 24.1 8.6e-14 50.8 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO34185.1 - 8.2e-10 37.4 7.5 0.069 11.2 0.2 5.2 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO34185.1 - 3.8e-08 32.0 0.2 0.0041 15.4 0.0 2.3 1 1 1 2 2 2 2 Cytochrome D1 heme domain Resistin PF06954.6 ETO34185.1 - 0.038 14.2 0.6 32 4.8 0.0 3.7 2 2 2 4 4 4 0 Resistin Str_synth PF03088.11 ETO34185.1 - 0.049 13.6 0.1 4.2 7.4 0.0 3.8 4 1 0 4 4 4 0 Strictosidine synthase Me-amine-dh_H PF06433.6 ETO34185.1 - 0.074 11.6 0.4 1.2 7.6 0.1 2.5 3 0 0 3 3 3 0 Methylamine dehydrogenase heavy chain (MADH) IBP39 PF11422.3 ETO34185.1 - 0.12 11.8 3.8 0.25 10.8 1.8 2.2 2 1 1 3 3 3 0 Initiator binding protein 39 kDa NTNH_C PF08470.5 ETO34185.1 - 2.1 7.9 12.8 0.14 11.8 2.2 2.8 2 1 1 3 3 3 0 Nontoxic nonhaemagglutinin C-terminal PD40 PF07676.7 ETO34185.1 - 5.8 6.6 10.2 49 3.7 0.0 5.0 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat GTP_EFTU PF00009.22 ETO34186.1 - 3.1e-34 118.0 0.1 4.5e-34 117.5 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 ETO34186.1 - 1.3e-09 38.1 0.3 5.1e-09 36.2 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 ETO34186.1 - 1.7e-09 37.6 0.1 3.9e-09 36.4 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 ETO34186.1 - 1.6e-08 34.0 0.1 3.7e-08 32.9 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Arf PF00025.16 ETO34186.1 - 0.029 13.6 1.1 2 7.6 0.0 3.1 2 1 0 3 3 3 0 ADP-ribosylation factor family Kelch_6 PF13964.1 ETO34187.1 - 7.6e-06 25.8 0.9 1.9 8.7 0.0 4.9 3 1 1 4 4 4 3 Kelch motif Kelch_1 PF01344.20 ETO34187.1 - 0.0059 16.1 0.5 9.7 5.8 0.0 4.2 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 ETO34187.1 - 0.16 11.9 1.5 8.2 6.5 0.0 3.7 5 0 0 5 5 5 0 Kelch motif WD40 PF00400.27 ETO34188.1 - 1.4e-30 104.0 15.2 4.3e-10 39.0 0.0 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO34188.1 - 4.4e-08 31.7 2.0 0.0014 16.8 0.2 2.7 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Stap_Strp_toxin PF01123.15 ETO34188.1 - 0.072 13.5 0.6 0.072 13.5 0.4 1.9 2 0 0 2 2 2 0 Staphylococcal/Streptococcal toxin, OB-fold domain FUR PF01475.14 ETO34188.1 - 1.5 8.7 7.5 0.8 9.6 0.5 2.9 3 0 0 3 3 3 0 Ferric uptake regulator family Kinesin PF00225.18 ETO34189.1 - 1.2e-25 89.9 0.1 1.4e-25 89.7 0.1 1.1 1 0 0 1 1 1 1 Kinesin motor domain Sigma70_ner PF04546.8 ETO34189.1 - 0.00017 21.2 1.2 0.00025 20.7 0.9 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region LamB PF02264.10 ETO34189.1 - 0.00055 19.1 0.1 0.00069 18.8 0.0 1.2 1 0 0 1 1 1 1 LamB porin CENP-B_dimeris PF09026.5 ETO34189.1 - 0.0095 16.1 2.1 0.017 15.3 1.5 1.4 1 0 0 1 1 1 1 Centromere protein B dimerisation domain AAA_22 PF13401.1 ETO34189.1 - 0.055 13.6 0.0 0.073 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF4611 PF15387.1 ETO34189.1 - 0.075 13.1 3.1 0.14 12.3 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Inositol_P PF00459.20 ETO34190.1 - 1e-14 54.5 0.0 1.4e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family Glutaredoxin PF00462.19 ETO34191.1 - 7.6e-33 112.3 0.0 1.7e-15 56.7 0.0 3.1 3 0 0 3 3 3 2 Glutaredoxin Thioredoxin PF00085.15 ETO34191.1 - 3.8e-17 61.8 0.1 1.7e-16 59.7 0.0 2.1 2 1 1 3 3 3 1 Thioredoxin Thioredoxin_8 PF13905.1 ETO34191.1 - 6.1e-06 26.2 0.8 0.035 14.2 0.0 3.8 3 1 1 4 4 4 2 Thioredoxin-like GST_N_3 PF13417.1 ETO34191.1 - 0.0015 18.7 0.0 0.46 10.7 0.0 2.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.1 ETO34191.1 - 0.0019 18.3 0.1 0.14 12.3 0.0 3.4 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 ETO34191.1 - 0.01 15.6 0.0 1 9.2 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin domain GN3L_Grn1 PF08701.6 ETO34191.1 - 0.034 14.0 0.9 0.083 12.8 0.6 1.6 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase ArsC PF03960.10 ETO34191.1 - 0.047 13.7 0.0 3.4 7.7 0.0 3.2 3 0 0 3 3 3 0 ArsC family HyaE PF07449.6 ETO34191.1 - 0.13 12.2 0.1 5 7.0 0.0 3.4 4 1 1 5 5 5 0 Hydrogenase-1 expression protein HyaE Endonuclease_5 PF04493.9 ETO34192.1 - 0.017 14.5 0.1 0.039 13.2 0.0 1.7 1 1 1 2 2 2 0 Endonuclease V G10 PF01125.12 ETO34192.1 - 0.13 11.7 0.3 0.32 10.5 0.1 1.6 1 1 1 2 2 2 0 G10 protein DUF848 PF05852.6 ETO34192.1 - 0.29 10.9 2.4 0.48 10.2 0.1 1.9 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Crystall PF00030.14 ETO34193.1 - 0.022 14.6 0.0 2.5 8.0 0.0 2.9 2 0 0 2 2 2 0 Beta/Gamma crystallin WD40 PF00400.27 ETO34194.1 - 1.5e-66 218.0 21.8 4.5e-11 42.1 0.0 8.6 8 2 0 8 8 8 7 WD domain, G-beta repeat PD40 PF07676.7 ETO34194.1 - 1.3e-05 24.7 13.0 0.5 10.0 0.0 6.7 9 0 0 9 9 9 3 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO34194.1 - 0.00017 21.1 0.1 0.0032 16.9 0.0 2.9 1 1 1 2 2 2 1 PQQ-like domain Nbas_N PF15492.1 ETO34194.1 - 0.00047 19.3 1.7 0.25 10.4 0.0 4.5 1 1 2 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Mid2 PF04478.7 ETO34194.1 - 0.0013 18.1 6.7 1.8 7.9 0.1 4.7 2 2 3 5 5 5 2 Mid2 like cell wall stress sensor DUF3892 PF13031.1 ETO34194.1 - 0.0028 18.0 0.5 0.53 10.7 0.0 3.5 2 1 1 3 3 3 1 Protein of unknown function (DUF3892) DUF1938 PF09153.5 ETO34194.1 - 0.0029 17.3 4.5 0.93 9.3 0.1 3.7 2 2 2 4 4 4 2 Domain of unknown function (DUF1938) DUF1652 PF07865.6 ETO34194.1 - 0.059 12.9 0.0 6.8 6.3 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1652) USP7_C2 PF14533.1 ETO34194.1 - 0.064 12.6 1.8 6.7 6.0 0.0 3.8 3 2 1 4 4 4 0 Ubiquitin-specific protease C-terminal WD40 PF00400.27 ETO34195.1 - 5.5e-171 549.1 49.5 9.8e-13 47.4 0.2 16.3 16 0 0 16 16 16 16 WD domain, G-beta repeat PQQ_2 PF13360.1 ETO34195.1 - 5e-08 32.6 1.1 0.00048 19.6 0.2 3.6 2 2 0 2 2 2 2 PQQ-like domain Cytochrom_D1 PF02239.11 ETO34195.1 - 3e-07 29.0 8.6 0.0012 17.1 0.1 5.6 2 2 4 7 7 7 3 Cytochrome D1 heme domain Str_synth PF03088.11 ETO34195.1 - 1.5e-06 28.1 0.3 8.8 6.4 0.0 7.0 7 0 0 7 7 7 2 Strictosidine synthase PD40 PF07676.7 ETO34195.1 - 3.4e-06 26.5 18.4 10 5.9 0.1 9.6 11 0 0 11 11 11 2 WD40-like Beta Propeller Repeat Pentapeptide_4 PF13599.1 ETO34195.1 - 1.1e-05 25.1 0.4 3.1e-05 23.6 0.3 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETO34195.1 - 6.8e-05 22.0 0.7 0.00015 20.9 0.5 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Mid2 PF04478.7 ETO34195.1 - 9.1e-05 21.9 21.9 1.8 7.9 0.0 8.6 6 3 5 11 11 11 4 Mid2 like cell wall stress sensor NYD-SP28_assoc PF14775.1 ETO34195.1 - 0.00012 21.7 12.3 48 3.7 0.0 10.7 12 0 0 12 12 12 0 Sperm tail C-terminal domain Pentapeptide_3 PF13576.1 ETO34195.1 - 0.0022 17.8 0.3 0.0022 17.8 0.2 2.4 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) TPR_12 PF13424.1 ETO34196.1 - 8.7e-27 92.8 16.6 1.6e-11 43.9 0.8 4.4 2 2 2 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO34196.1 - 1.4e-24 83.9 17.9 5.6e-05 22.7 0.2 6.2 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETO34196.1 - 1.5e-23 81.3 30.4 2.9e-06 26.6 1.3 6.2 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETO34196.1 - 6.4e-19 67.3 35.9 9.6e-08 31.5 1.2 4.2 1 1 4 5 5 5 5 TPR repeat TPR_10 PF13374.1 ETO34196.1 - 1.1e-17 63.2 0.0 1.7e-05 24.6 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO34196.1 - 2.5e-17 61.2 32.3 9.6e-05 21.9 0.6 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.1 ETO34196.1 - 4.2e-14 51.1 8.5 0.0017 18.0 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETO34196.1 - 9.7e-10 37.8 10.3 0.99 9.7 0.0 6.6 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO34196.1 - 1.1e-09 38.7 0.0 0.002 18.7 0.0 3.7 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO34196.1 - 5.6e-07 29.6 8.4 0.11 13.0 0.1 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO34196.1 - 5.2e-06 26.6 0.0 13 6.7 0.0 4.9 5 1 1 6 6 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETO34196.1 - 4.8e-05 23.6 0.6 0.04 14.2 0.2 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO34196.1 - 0.00031 20.7 23.1 0.0081 16.2 1.4 3.4 1 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 ETO34196.1 - 0.0016 18.2 8.3 3.9 7.4 0.1 4.4 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_9 PF13371.1 ETO34196.1 - 0.09 12.6 0.0 31 4.5 0.0 3.6 5 0 0 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.4 ETO34196.1 - 0.23 10.8 7.1 2.2 7.6 0.0 3.7 2 2 2 4 4 4 0 26S proteasome subunit RPN7 Foie-gras_1 PF11817.3 ETO34196.1 - 1.1 8.6 4.3 1.4 8.3 0.1 2.7 2 1 0 3 3 3 0 Foie gras liver health family 1 Sel1 PF08238.7 ETO34196.1 - 3 8.6 0.0 3 8.6 0.0 5.4 6 1 0 6 6 5 0 Sel1 repeat RVT_1 PF00078.22 ETO34197.1 - 8.6e-12 44.8 0.5 3.5e-06 26.5 0.0 3.2 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4583 PF15190.1 ETO34198.1 - 0.094 12.3 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4583) Topoisom_I PF01028.15 ETO34200.1 - 1.3e-80 269.8 7.0 1.3e-80 269.8 4.8 2.0 2 1 1 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.10 ETO34200.1 - 7.1e-80 267.3 4.2 7.1e-80 267.3 2.9 3.5 2 1 1 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.1 ETO34200.1 - 1.1e-31 108.3 0.8 1.1e-31 108.3 0.6 2.1 2 0 0 2 2 2 1 C-terminal topoisomerase domain Rabaptin PF03528.10 ETO34200.1 - 0.00055 19.8 2.2 0.00055 19.8 1.5 3.5 3 1 0 3 3 3 1 Rabaptin BTB_2 PF02214.17 ETO34200.1 - 0.042 14.0 0.7 0.13 12.5 0.5 1.8 1 0 0 1 1 1 0 BTB/POZ domain UPF0278 PF08745.6 ETO34200.1 - 0.35 10.0 0.0 0.35 10.0 0.0 2.7 4 0 0 4 4 4 0 UPF0278 family CDT1 PF08839.6 ETO34200.1 - 0.62 9.9 11.1 0.69 9.8 0.1 3.4 3 0 0 3 3 3 0 DNA replication factor CDT1 like Cep57_CLD_2 PF14197.1 ETO34200.1 - 0.75 9.7 8.2 0.52 10.3 2.2 2.8 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Menin PF05053.8 ETO34201.1 - 0.033 12.3 0.6 0.031 12.4 0.4 1.0 1 0 0 1 1 1 0 Menin CENP-C_mid PF15620.1 ETO34201.1 - 0.036 13.7 8.6 0.039 13.6 5.9 1.2 1 0 0 1 1 1 0 Centromere assembly component CENP-C middle DNMT3B-binding region AIF_C PF14721.1 ETO34201.1 - 0.15 12.2 2.0 0.17 12.1 1.4 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term RP-C_C PF11800.3 ETO34201.1 - 0.36 10.4 3.0 0.39 10.3 2.1 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF2500 PF10694.4 ETO34201.1 - 0.49 10.4 3.2 2.5 8.1 2.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2500) YqfQ PF14181.1 ETO34201.1 - 1.9 8.4 9.6 2.7 8.0 6.7 1.1 1 0 0 1 1 1 0 YqfQ-like protein WD40 PF00400.27 ETO34203.1 - 9.5e-63 206.0 24.7 1.6e-10 40.4 0.6 6.8 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO34203.1 - 5.2e-12 44.6 8.3 0.024 12.7 0.0 5.9 1 1 5 6 6 6 6 Nucleoporin Nup120/160 SUKH_5 PF14567.1 ETO34203.1 - 0.015 14.7 0.3 6.5 6.2 0.0 3.5 2 1 1 3 3 3 0 SMI1-KNR4 cell-wall U-box PF04564.10 ETO34204.1 - 2.8e-09 36.8 0.0 8.6e-09 35.2 0.0 1.9 1 1 0 1 1 1 1 U-box domain Vac_ImportDeg PF09783.4 ETO34205.1 - 0.021 14.2 2.6 0.025 14.0 1.8 1.2 1 0 0 1 1 1 0 Vacuolar import and degradation protein WD40 PF00400.27 ETO34206.1 - 1.9e-07 30.6 0.0 0.00063 19.5 0.0 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat PD40 PF07676.7 ETO34206.1 - 1.1e-05 25.0 1.5 0.021 14.4 0.0 4.9 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat WD40 PF00400.27 ETO34207.1 - 7.9e-146 469.3 42.0 8.5e-13 47.6 0.1 15.7 15 1 0 15 15 15 15 WD domain, G-beta repeat Nup160 PF11715.3 ETO34207.1 - 1.9e-12 46.1 24.8 0.54 8.3 0.0 11.9 1 1 9 11 11 11 7 Nucleoporin Nup120/160 NACHT PF05729.7 ETO34207.1 - 7.7e-10 38.6 0.0 1.4e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO34207.1 - 1.3e-05 25.5 1.4 0.00011 22.4 0.1 3.2 1 1 1 2 2 2 1 AAA domain PQQ_2 PF13360.1 ETO34207.1 - 0.00017 21.1 1.3 0.031 13.7 0.2 4.0 1 1 1 3 3 3 1 PQQ-like domain AAA_22 PF13401.1 ETO34207.1 - 0.011 15.8 0.0 0.033 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain NtA PF03146.10 ETO34207.1 - 0.043 13.4 0.5 3.6 7.2 0.0 3.9 3 1 0 4 4 4 0 Agrin NtA domain AAA_17 PF13207.1 ETO34207.1 - 0.052 14.3 1.8 0.41 11.4 0.0 3.2 2 1 1 3 3 2 0 AAA domain AAA PF00004.24 ETO34207.1 - 0.058 13.6 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Inhibitor_I53 PF11714.3 ETO34207.1 - 0.12 12.3 0.1 0.33 10.9 0.1 1.6 1 0 0 1 1 1 0 Thrombin inhibitor Madanin Fibrinogen_aC PF12160.3 ETO34207.1 - 0.14 11.6 4.4 9.9 5.7 0.1 3.9 3 1 1 4 4 4 0 Fibrinogen alpha C domain PD40 PF07676.7 ETO34207.1 - 0.34 10.6 33.2 30 4.4 0.1 10.9 12 0 0 12 12 12 0 WD40-like Beta Propeller Repeat Kelch_6 PF13964.1 ETO34208.1 - 0.00096 19.2 0.4 0.066 13.4 0.0 3.3 2 1 1 3 3 3 1 Kelch motif Kelch_5 PF13854.1 ETO34208.1 - 0.0012 18.7 0.2 1.6 8.7 0.0 2.9 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 ETO34208.1 - 0.0036 16.8 0.1 0.044 13.3 0.0 2.6 2 0 0 2 2 2 1 Kelch motif GF_recep_IV PF14843.1 ETO34208.1 - 0.062 12.9 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Growth factor receptor domain IV Kelch_2 PF07646.10 ETO34208.1 - 0.071 12.8 0.4 1.2 9.0 0.0 2.9 3 1 0 3 3 3 0 Kelch motif WD40 PF00400.27 ETO34209.1 - 2.2e-77 252.3 14.0 5.1e-13 48.3 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO34209.1 - 2.2e-09 36.0 4.1 0.15 10.1 0.2 5.1 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO34209.1 - 2.8e-07 29.6 10.3 0.064 11.9 0.5 5.4 1 1 3 4 4 4 3 Nup133 N terminal like PD40 PF07676.7 ETO34209.1 - 3.4e-07 29.7 4.0 11 5.8 0.0 6.1 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO34209.1 - 4.8e-06 26.2 0.1 8.6e-05 22.0 0.1 2.6 1 1 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO34209.1 - 6.5e-05 21.4 1.1 0.0016 16.8 0.0 2.7 1 1 0 3 3 3 1 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO34209.1 - 7.9e-05 21.8 0.3 0.12 11.4 0.0 3.8 1 1 3 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Resistin PF06954.6 ETO34209.1 - 0.00012 22.2 0.7 7 7.0 0.0 4.0 2 1 1 3 3 3 1 Resistin Ricin_B_lectin PF00652.17 ETO34209.1 - 0.002 18.1 4.3 1.4 8.9 1.8 3.5 1 1 2 3 3 3 2 Ricin-type beta-trefoil lectin domain Hira PF07569.6 ETO34209.1 - 0.002 17.3 0.8 2.5 7.2 0.0 3.5 3 2 1 4 4 4 2 TUP1-like enhancer of split Proteasome_A_N PF10584.4 ETO34209.1 - 0.014 14.7 8.5 25 4.3 0.0 6.0 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature DUF1797 PF08796.5 ETO34209.1 - 0.029 14.2 0.0 14 5.5 0.0 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF1797) PQQ PF01011.16 ETO34209.1 - 0.061 12.8 0.0 42 3.9 0.0 4.0 4 0 0 4 4 4 0 PQQ enzyme repeat WD40 PF00400.27 ETO34210.1 - 4.7e-16 57.9 8.2 3.9e-11 42.3 0.2 2.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO34210.1 - 0.031 12.4 0.5 0.32 9.0 0.4 1.9 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO34211.1 - 6.8e-07 29.1 2.0 0.69 10.1 0.0 5.5 5 1 1 6 6 6 2 Kelch motif Kelch_2 PF07646.10 ETO34211.1 - 0.00071 19.2 4.1 0.55 10.0 0.2 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 ETO34211.1 - 0.00081 19.2 0.1 6.7 6.7 0.0 4.7 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.20 ETO34211.1 - 0.00093 18.6 7.1 0.099 12.2 0.1 4.9 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.1 ETO34211.1 - 0.029 14.1 3.0 2 8.2 0.1 3.8 3 1 1 4 4 4 0 Galactose oxidase, central domain WD40 PF00400.27 ETO34212.1 - 8.4e-38 126.9 26.3 5.8e-13 48.1 0.2 7.0 6 1 1 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO34212.1 - 7.4e-09 34.2 6.0 0.00057 18.1 0.9 4.7 2 2 0 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO34212.1 - 8.8e-05 21.4 14.4 0.066 11.9 0.4 3.3 1 1 2 3 3 3 3 Nup133 N terminal like DUF4221 PF13970.1 ETO34212.1 - 0.004 16.5 4.4 0.0056 16.0 0.3 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4221) WD40 PF00400.27 ETO34214.1 - 1e-39 132.9 12.1 1.5e-09 37.3 0.0 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO34214.1 - 7.1e-10 37.6 2.0 0.0023 16.1 0.0 3.4 1 1 2 3 3 3 3 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO34214.1 - 0.0014 18.3 0.7 0.19 11.4 0.0 2.7 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.1 ETO34214.1 - 0.18 12.1 1.6 57 4.1 0.0 3.4 4 0 0 4 4 4 0 PQQ-like domain Kelch_5 PF13854.1 ETO34215.1 - 3.3e-05 23.7 0.4 0.041 13.8 0.1 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.1 ETO34215.1 - 0.004 17.2 0.1 0.11 12.7 0.0 2.2 2 0 0 2 2 2 1 Kelch motif GF_recep_IV PF14843.1 ETO34215.1 - 0.011 15.3 0.5 0.013 15.0 0.4 1.1 1 0 0 1 1 1 0 Growth factor receptor domain IV Kelch_2 PF07646.10 ETO34215.1 - 0.067 12.9 0.2 0.92 9.3 0.1 2.3 2 0 0 2 2 2 0 Kelch motif EGF_3 PF12947.2 ETO34215.1 - 0.092 12.7 2.1 0.21 11.5 1.5 1.6 1 0 0 1 1 1 0 EGF domain Phage_GP20 PF06810.6 ETO34216.1 - 0.0026 17.2 3.1 0.0026 17.2 2.1 3.6 1 1 1 3 3 3 2 Phage minor structural protein GP20 Cep57_MT_bd PF06657.8 ETO34216.1 - 0.0078 16.1 2.3 0.0078 16.1 1.6 3.9 4 2 0 4 4 4 2 Centrosome microtubule-binding domain of Cep57 DUF1212 PF06738.7 ETO34216.1 - 0.66 9.4 2.4 0.87 9.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) GTP_EFTU PF00009.22 ETO34216.1 - 0.96 8.8 8.2 1.7 8.0 0.5 2.9 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Fib_alpha PF08702.5 ETO34217.1 - 0.23 11.5 3.2 0.43 10.7 0.5 2.1 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Kinesin PF00225.18 ETO34218.1 - 3.2e-24 85.2 3.0 3.2e-24 85.2 2.1 1.8 2 0 0 2 2 2 1 Kinesin motor domain RVT_1 PF00078.22 ETO34218.1 - 4.3e-12 45.8 0.3 1.7e-09 37.3 0.0 3.4 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Mu-like_Com PF10122.4 ETO34218.1 - 0.0016 17.4 0.8 0.0044 16.0 0.5 1.7 1 0 0 1 1 1 1 Mu-like prophage protein Com zf-BED PF02892.10 ETO34218.1 - 0.014 15.1 0.3 0.049 13.3 0.2 2.0 1 0 0 1 1 1 0 BED zinc finger Mito_carr PF00153.22 ETO34221.1 - 3.4e-40 135.6 5.7 7.5e-16 57.6 0.1 4.3 4 0 0 4 4 4 4 Mitochondrial carrier protein Ank_2 PF12796.2 ETO34223.1 - 2.1e-06 27.9 0.1 5.2e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO34223.1 - 2.5e-06 26.9 0.7 1.1e-05 24.9 0.1 2.3 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.1 ETO34223.1 - 4.1e-05 23.6 0.0 7.2e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO34223.1 - 4.2e-05 23.3 0.4 0.00049 20.0 0.1 2.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 ETO34223.1 - 0.0012 19.2 0.1 0.0024 18.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Cytochrom_C_2 PF01322.15 ETO34225.1 - 0.018 15.5 1.8 0.057 13.9 0.8 2.2 2 0 0 2 2 2 0 Cytochrome C' WD40 PF00400.27 ETO34226.1 - 2.4e-08 33.5 3.7 0.00025 20.7 0.1 3.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Saw1 PF11561.3 ETO34227.1 - 0.0018 17.6 1.4 0.0023 17.3 0.9 1.2 1 0 0 1 1 1 1 Single strand annealing-weakened 1 Sporozoite_P67 PF05642.6 ETO34227.1 - 0.0037 15.2 0.6 0.0038 15.1 0.4 1.0 1 0 0 1 1 1 1 Sporozoite P67 surface antigen SIN1 PF05422.7 ETO34227.1 - 0.014 13.9 2.5 0.015 13.8 1.7 1.0 1 0 0 1 1 1 0 Stress-activated map kinase interacting protein 1 (SIN1) DUF1779 PF08680.5 ETO34227.1 - 0.016 15.0 1.8 0.018 14.9 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1779) FAM176 PF14851.1 ETO34227.1 - 0.018 14.7 1.3 0.021 14.5 0.9 1.2 1 0 0 1 1 1 0 FAM176 family DUF506 PF04720.7 ETO34227.1 - 0.034 13.7 0.7 0.034 13.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF506) PRP21_like_P PF12230.3 ETO34227.1 - 0.077 12.4 8.1 0.093 12.2 5.6 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein Protocadherin PF08374.6 ETO34227.1 - 0.1 12.2 5.1 0.11 12.1 3.6 1.1 1 0 0 1 1 1 0 Protocadherin FAM183 PF14886.1 ETO34227.1 - 0.24 11.9 3.9 0.25 11.8 1.3 1.7 1 1 0 2 2 2 0 FAM183A and FAM183B related Ycf1 PF05758.7 ETO34227.1 - 0.26 8.9 3.0 0.27 8.8 2.1 1.0 1 0 0 1 1 1 0 Ycf1 Peptidase_U57 PF05582.7 ETO34227.1 - 0.53 9.2 5.0 0.65 8.9 3.4 1.1 1 0 0 1 1 1 0 YabG peptidase U57 SID-1_RNA_chan PF13965.1 ETO34227.1 - 0.53 8.3 3.9 0.54 8.3 2.7 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Kelch_6 PF13964.1 ETO34228.1 - 0.00018 21.4 5.1 0.0047 17.0 0.1 4.4 6 0 0 6 6 6 1 Kelch motif Kelch_4 PF13418.1 ETO34228.1 - 0.00065 19.4 1.0 0.0056 16.4 0.0 2.9 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO34228.1 - 0.0038 16.7 2.7 0.02 14.4 0.1 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO34228.1 - 0.085 12.6 4.9 0.49 10.2 0.0 3.6 3 1 1 4 4 4 0 Kelch motif WD40 PF00400.27 ETO34229.1 - 3.9e-08 32.8 6.5 9.4e-05 22.1 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat TSP9 PF11493.3 ETO34229.1 - 0.001 19.5 2.5 0.033 14.7 0.2 2.6 2 0 0 2 2 2 1 Thylakoid soluble phosphoprotein TSP9 Menin PF05053.8 ETO34229.1 - 0.29 9.2 5.8 0.46 8.5 4.0 1.3 1 0 0 1 1 1 0 Menin Kinesin PF00225.18 ETO34230.1 - 0.012 14.3 0.0 0.014 14.1 0.0 1.1 1 0 0 1 1 1 0 Kinesin motor domain CLAMP PF14769.1 ETO34231.1 - 0.072 13.2 0.4 0.1 12.7 0.3 1.3 1 0 0 1 1 1 0 Flagellar C1a complex subunit C1a-32 DUF3916 PF13079.1 ETO34234.1 - 0.047 13.3 0.4 0.15 11.7 0.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3916) YvfG PF09628.5 ETO34235.1 - 0.042 13.9 0.2 0.068 13.3 0.2 1.4 1 1 0 1 1 1 0 YvfG protein G-alpha PF00503.15 ETO34237.1 - 6.9e-29 100.7 1.4 8.4e-29 100.4 1.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO34237.1 - 5.7e-05 22.4 0.3 0.00012 21.4 0.2 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family SR-25 PF10500.4 ETO34238.1 - 2.9e-07 30.1 12.9 2.9e-07 30.1 9.0 2.5 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein zf-RanBP PF00641.13 ETO34238.1 - 1.7e-06 26.9 1.8 3.9e-06 25.8 1.2 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF1777 PF08648.7 ETO34238.1 - 3.2e-06 27.0 33.0 3.2e-06 27.0 22.9 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) Ion_trans PF00520.26 ETO34239.1 - 4.9e-34 117.3 16.2 7.1e-34 116.8 11.2 1.3 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.7 ETO34239.1 - 4.2e-06 25.4 9.1 6.2e-06 24.8 6.3 1.3 1 0 0 1 1 1 1 Polycystin cation channel WD40 PF00400.27 ETO34240.1 - 1.4e-14 53.2 0.2 8.6e-13 47.6 0.0 2.3 2 1 0 2 2 2 1 WD domain, G-beta repeat Beta_helix PF13229.1 ETO34240.1 - 0.016 14.9 0.9 0.022 14.5 0.6 1.2 1 0 0 1 1 1 0 Right handed beta helix region Nup160 PF11715.3 ETO34240.1 - 0.036 12.2 0.0 0.036 12.2 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 WD40 PF00400.27 ETO34241.1 - 5.6e-74 241.6 15.9 2.4e-13 49.3 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO34241.1 - 6.4e-12 45.5 0.2 0.00032 20.4 0.0 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO34241.1 - 1.1e-07 30.4 3.8 0.26 9.3 0.0 4.9 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO34241.1 - 1.7e-07 29.9 2.2 0.084 11.1 0.0 3.1 1 1 2 3 3 3 3 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO34241.1 - 1.4e-06 27.9 0.2 0.004 16.6 0.0 3.4 2 1 0 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 ETO34241.1 - 1.8e-06 26.9 9.2 0.53 8.9 0.4 5.0 2 2 2 5 5 5 4 Nup133 N terminal like PD40 PF07676.7 ETO34241.1 - 3.5e-06 26.5 2.0 9.6 6.0 0.1 5.9 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO34241.1 - 0.00013 22.1 0.1 11 6.3 0.0 4.5 2 2 3 5 5 5 2 Resistin Proteasome_A_N PF10584.4 ETO34241.1 - 0.011 15.0 4.2 8.1 5.8 0.1 4.0 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature DUF3601 PF12208.3 ETO34241.1 - 0.011 15.6 0.0 1.8 8.5 0.0 3.9 4 2 1 5 5 5 0 Domain of unknown function (DUF3601) PLD_C PF12357.3 ETO34241.1 - 0.032 13.7 0.1 56 3.3 0.0 4.1 4 0 0 4 4 4 0 Phospholipase D C terminal DUF3732 PF12532.3 ETO34241.1 - 0.035 13.6 0.3 16 4.9 0.0 3.8 4 1 1 5 5 5 0 Protein of unknown function (DUF3732) WD40 PF00400.27 ETO34242.1 - 2.7e-63 207.7 18.7 5.4e-11 41.9 0.7 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO34242.1 - 8.4e-14 50.5 5.4 0.013 13.7 0.1 5.8 1 1 4 5 5 5 5 Nucleoporin Nup120/160 Cu-oxidase_2 PF07731.9 ETO34242.1 - 0.002 17.6 0.0 0.0074 15.8 0.0 2.0 1 0 0 1 1 1 1 Multicopper oxidase DUF2317 PF10079.4 ETO34242.1 - 0.034 12.7 7.8 0.047 12.3 5.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) DUF3601 PF12208.3 ETO34242.1 - 0.044 13.7 0.0 4.7 7.2 0.0 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF3601) DUF3373 PF11853.3 ETO34242.1 - 0.63 8.5 5.9 0.97 7.8 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF3584 PF12128.3 ETO34242.1 - 2.2 5.5 16.2 3 5.0 11.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Atg14 PF10186.4 ETO34242.1 - 4 6.3 19.3 9.3 5.0 13.4 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 YojJ PF10372.4 ETO34242.1 - 5.9 6.8 8.6 3.9 7.4 2.8 2.3 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus COX16 PF14138.1 ETO34242.1 - 9.2 6.5 8.8 1.7 8.8 2.7 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein COX16 IncA PF04156.9 ETO34242.1 - 9.8 5.7 16.6 19 4.7 11.5 1.5 1 0 0 1 1 1 0 IncA protein Na_trans_assoc PF06512.8 ETO34243.1 - 0.006 16.5 2.3 0.0071 16.3 1.6 1.1 1 0 0 1 1 1 1 Sodium ion transport-associated Neur_chan_memb PF02932.11 ETO34243.1 - 0.015 15.2 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4093 PF13331.1 ETO34243.1 - 0.038 14.1 0.2 0.064 13.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4093) Secretin_N_2 PF07655.8 ETO34244.1 - 0.0085 16.4 8.9 0.011 16.0 6.2 1.2 1 0 0 1 1 1 1 Secretin N-terminal domain DUF912 PF06024.7 ETO34244.1 - 0.012 15.5 1.6 0.017 15.1 1.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) STT3 PF02516.9 ETO34244.1 - 0.015 14.2 0.1 0.018 14.0 0.1 1.0 1 0 0 1 1 1 0 Oligosaccharyl transferase STT3 subunit TerD PF02342.13 ETO34244.1 - 0.069 12.4 0.1 0.08 12.2 0.0 1.1 1 0 0 1 1 1 0 TerD domain Pex14_N PF04695.8 ETO34244.1 - 3.5 7.6 7.0 4.6 7.2 4.8 1.3 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mitofilin PF09731.4 ETO34245.1 - 0.0039 15.9 18.9 0.0052 15.5 13.1 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF4475 PF14753.1 ETO34245.1 - 0.059 12.8 6.1 0.086 12.3 3.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4475) Spore_III_AB PF09548.5 ETO34245.1 - 0.14 11.9 3.0 0.13 12.0 0.3 2.0 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Macoilin PF09726.4 ETO34245.1 - 1 7.5 16.9 1.3 7.2 11.7 1.1 1 0 0 1 1 1 0 Transmembrane protein SR-25 PF10500.4 ETO34245.1 - 3.2 7.1 20.8 0.12 11.7 10.6 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CactinC_cactus PF09732.4 ETO34247.1 - 0.93 9.1 7.4 1.2 8.7 5.2 1.1 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein Poxvirus_B22R PF04395.7 ETO34249.1 - 0.092 12.2 9.5 0.057 12.9 5.3 1.6 2 0 0 2 2 2 0 Poxvirus B22R protein Cys_knot PF00007.17 ETO34249.1 - 2.2 8.4 9.7 2.7 8.1 0.1 2.7 2 1 0 2 2 2 0 Cystine-knot domain HAND PF09110.6 ETO34250.1 - 0.016 15.5 6.7 0.02 15.2 4.6 1.2 1 0 0 1 1 1 0 HAND PhnI PF05861.7 ETO34250.1 - 0.033 12.6 0.2 0.036 12.5 0.1 1.0 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnI) Endonuc-dimeris PF09124.5 ETO34250.1 - 0.049 13.2 1.4 0.049 13.2 1.0 1.9 2 0 0 2 2 2 0 T4 recombination endonuclease VII, dimerisation DUF443 PF04276.7 ETO34250.1 - 0.12 11.7 3.3 0.072 12.5 1.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF443) EphA2_TM PF14575.1 ETO34250.1 - 0.14 12.6 0.3 0.14 12.6 0.2 1.9 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SID-1_RNA_chan PF13965.1 ETO34250.1 - 0.19 9.8 2.8 0.22 9.6 2.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Protocadherin PF08374.6 ETO34250.1 - 0.25 10.9 4.7 0.27 10.8 3.3 1.1 1 0 0 1 1 1 0 Protocadherin DUF3573 PF12097.3 ETO34250.1 - 1.5 7.3 5.4 1.5 7.3 3.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) CIAPIN1 PF05093.8 ETO34250.1 - 2.8 8.0 6.1 4.6 7.3 4.3 1.3 1 0 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Stap_Strp_toxin PF01123.15 ETO34250.1 - 7.4 7.1 8.3 10 6.6 5.8 1.3 1 0 0 1 1 1 0 Staphylococcal/Streptococcal toxin, OB-fold domain YajC PF02699.10 ETO34250.1 - 7.7 6.2 7.1 22 4.8 4.9 1.9 1 1 0 1 1 1 0 Preprotein translocase subunit DUF922 PF06037.6 ETO34251.1 - 0.037 13.3 1.2 0.043 13.1 0.8 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) DUF4448 PF14610.1 ETO34251.1 - 1.5 8.2 5.2 1.6 8.1 3.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) His_kinase PF06580.8 ETO34252.1 - 0.017 15.0 0.3 0.068 13.0 0.2 2.0 1 0 0 1 1 1 0 Histidine kinase TBCA PF02970.11 ETO34252.1 - 0.037 14.1 0.6 0.092 12.8 0.0 2.0 2 0 0 2 2 2 0 Tubulin binding cofactor A TLD PF07534.11 ETO34253.1 - 1.2e-07 31.7 0.2 2.4e-07 30.8 0.2 1.6 1 0 0 1 1 1 1 TLD SPX PF03105.14 ETO34254.1 - 0.0035 17.1 13.5 0.005 16.6 9.4 1.1 1 0 0 1 1 1 1 SPX domain XAP5 PF04921.9 ETO34254.1 - 0.076 12.5 7.0 0.12 11.9 4.9 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator MutS_III PF05192.13 ETO34254.1 - 1.1 9.0 5.6 1.5 8.6 3.8 1.3 1 1 0 1 1 1 0 MutS domain III Zip PF02535.17 ETO34255.1 - 0.093 11.7 2.0 0.13 11.2 1.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Daxx PF03344.10 ETO34255.1 - 1.1 7.7 25.3 0.034 12.6 13.6 1.4 2 0 0 2 2 2 0 Daxx Family Peptidase_M24 PF00557.19 ETO34256.1 - 2.7e-19 69.5 0.0 5.4e-18 65.3 0.0 2.2 1 1 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 ETO34256.1 - 3.6e-18 65.2 0.0 5.9e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain NUC153 PF08159.7 ETO34258.1 - 3.6e-05 23.2 1.4 8.4e-05 22.0 1.0 1.6 1 0 0 1 1 1 1 NUC153 domain Utp14 PF04615.8 ETO34259.1 - 0.11 10.6 25.8 0.14 10.3 17.9 1.1 1 0 0 1 1 1 0 Utp14 protein Peptidase_M24 PF00557.19 ETO34260.1 - 0.0035 16.9 0.0 0.0049 16.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 VWA_2 PF13519.1 ETO34262.1 - 1.1e-05 25.6 0.0 1.3e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Med25_VWA PF11265.3 ETO34262.1 - 0.096 11.7 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A DUF2039 PF10217.4 ETO34264.1 - 0.0044 16.9 0.4 0.015 15.2 0.3 1.9 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) TPR_12 PF13424.1 ETO34264.1 - 0.0068 16.3 2.1 0.039 13.8 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.13 ETO34264.1 - 0.034 14.0 0.2 0.11 12.3 0.1 1.9 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.1 ETO34264.1 - 0.11 12.2 2.4 0.3 10.7 0.3 2.7 2 1 0 2 2 2 0 TPR repeat NHL PF01436.16 ETO34264.1 - 0.15 12.0 2.2 0.65 10.0 0.1 3.1 3 0 0 3 3 3 0 NHL repeat TPR_1 PF00515.23 ETO34264.1 - 0.52 10.0 6.1 0.37 10.4 0.4 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETO34264.1 - 1 9.4 8.5 0.21 11.5 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.27 ETO34265.1 - 0.016 15.1 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 WD domain, G-beta repeat DapH_N PF08503.5 ETO34265.1 - 0.022 14.8 0.6 0.064 13.3 0.4 1.8 1 0 0 1 1 1 0 Tetrahydrodipicolinate succinyltransferase N-terminal CHU_C PF13585.1 ETO34265.1 - 0.077 12.8 0.9 0.24 11.2 0.0 2.3 2 0 0 2 2 2 0 C-terminal domain of CHU protein family DUF2368 PF10166.4 ETO34265.1 - 0.51 9.9 3.8 2.2 7.9 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) EMP24_GP25L PF01105.19 ETO34266.1 - 1.1e-25 90.3 0.5 1.8e-25 89.7 0.1 1.4 1 1 1 2 2 2 1 emp24/gp25L/p24 family/GOLD RSS_P20 PF11757.3 ETO34266.1 - 0.091 12.8 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like Zip PF02535.17 ETO34267.1 - 0.18 10.7 1.5 0.38 9.6 1.0 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter YqfQ PF14181.1 ETO34267.1 - 0.47 10.4 4.4 0.9 9.5 3.0 1.4 1 0 0 1 1 1 0 YqfQ-like protein tRNA-synt_2 PF00152.15 ETO34268.1 - 4.3e-40 137.4 0.1 1.2e-39 136.0 0.1 1.6 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2 PF00152.15 ETO34269.1 - 1.2e-09 37.4 0.3 1.2e-09 37.4 0.2 2.6 3 0 0 3 3 3 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 ETO34269.1 - 1.3e-09 37.7 0.0 2.8e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti-like PF12869.2 ETO34269.1 - 0.084 12.3 0.0 0.37 10.2 0.0 2.1 1 1 0 1 1 1 0 tRNA_anti-like Clathrin_H_link PF13838.1 ETO34270.1 - 0.28 11.0 2.0 2.9 7.8 0.1 3.5 3 0 0 3 3 3 0 Clathrin-H-link DUF2009 PF09418.5 ETO34271.1 - 0.029 13.1 0.2 0.032 13.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) TPR_7 PF13176.1 ETO34271.1 - 0.12 12.2 0.2 13 5.8 0.1 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETO34271.1 - 0.13 12.1 1.2 0.52 10.2 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Copper-bind PF00127.15 ETO34272.1 - 0.13 12.4 0.1 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Kelch_6 PF13964.1 ETO34273.1 - 4.2e-07 29.8 0.2 0.0011 19.0 0.2 2.7 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.20 ETO34273.1 - 2.3e-06 27.0 0.7 0.0014 18.1 0.3 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.10 ETO34273.1 - 4.7e-06 26.1 0.1 0.0017 18.0 0.1 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 ETO34273.1 - 3e-05 23.7 0.1 0.078 12.7 0.0 2.3 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO34273.1 - 0.018 15.1 0.0 0.13 12.4 0.0 2.1 2 0 0 2 2 2 0 Galactose oxidase, central domain DUF2414 PF10309.4 ETO34273.1 - 0.072 12.7 0.5 0.15 11.7 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2414) Herpes_UL3 PF03369.8 ETO34273.1 - 0.075 13.0 0.5 0.13 12.2 0.3 1.3 1 0 0 1 1 1 0 Herpesvirus UL3 protein DUF4577 PF15145.1 ETO34274.1 - 0.035 14.0 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) WD40 PF00400.27 ETO34275.1 - 6e-63 206.6 12.2 1.6e-12 46.7 0.5 6.5 5 1 1 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO34275.1 - 2.5e-05 22.6 0.5 0.12 10.5 0.0 3.0 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO34275.1 - 0.00016 20.1 1.0 0.00051 18.4 0.0 2.2 2 1 1 3 3 3 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO34275.1 - 0.00068 18.4 8.5 0.0026 16.5 1.4 2.9 1 1 1 2 2 2 2 Nup133 N terminal like PD40 PF07676.7 ETO34275.1 - 0.018 14.6 2.3 6.8 6.4 0.1 3.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Myco_haema PF05692.7 ETO34275.1 - 0.025 13.2 0.3 1.9 7.1 0.2 2.2 2 0 0 2 2 2 0 Mycoplasma haemagglutinin Resistin PF06954.6 ETO34275.1 - 0.057 13.7 0.1 7.9 6.8 0.0 2.8 2 1 0 2 2 2 0 Resistin TMCO5 PF14992.1 ETO34275.1 - 0.06 12.4 1.5 0.093 11.8 1.0 1.2 1 0 0 1 1 1 0 TMCO5 family Proteasome_A_N PF10584.4 ETO34275.1 - 0.54 9.6 3.4 17 4.8 0.2 2.9 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature Ras PF00071.17 ETO34276.1 - 3.1e-22 78.7 0.9 5.7e-22 77.8 0.7 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO34276.1 - 4.2e-05 24.0 0.1 8.2e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Miro-like protein OKR_DC_1_N PF03709.10 ETO34276.1 - 0.0076 16.3 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, N-terminal domain GTP_EFTU PF00009.22 ETO34276.1 - 0.0088 15.4 0.1 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 ETO34276.1 - 0.016 14.4 0.1 0.026 13.7 0.1 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family Methylase_S PF01420.14 ETO34279.1 - 0.021 14.8 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 Type I restriction modification DNA specificity domain Metallophos_2 PF12850.2 ETO34281.1 - 0.012 15.4 0.2 0.033 14.0 0.1 2.0 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain RicinB_lectin_2 PF14200.1 ETO34281.1 - 0.024 14.9 0.2 1 9.7 0.0 2.5 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Metallophos PF00149.23 ETO34281.1 - 0.038 13.3 16.6 0.59 9.5 11.6 2.4 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase Peptidase_M50 PF02163.17 ETO34283.1 - 0.09 11.7 3.0 0.26 10.2 2.1 1.7 1 1 0 1 1 1 0 Peptidase family M50 DUF3469 PF11952.3 ETO34284.1 - 0.022 14.4 0.9 4.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3469) Kelch_6 PF13964.1 ETO34285.1 - 8.9e-09 35.1 7.8 0.00015 21.8 1.0 4.1 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO34285.1 - 3.6e-07 29.6 6.9 1.5e-05 24.4 0.5 4.0 4 1 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO34285.1 - 1.3e-06 27.8 2.7 0.0017 18.0 0.1 4.3 5 0 0 5 5 5 1 Kelch motif Kelch_5 PF13854.1 ETO34285.1 - 1.4e-06 28.1 2.8 0.048 13.6 0.6 4.5 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO34285.1 - 1.7e-06 27.7 0.4 0.0001 22.0 0.0 3.4 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO34285.1 - 0.0016 18.5 0.1 0.032 14.3 0.0 3.1 3 0 0 3 3 3 1 Galactose oxidase, central domain DUF2414 PF10309.4 ETO34285.1 - 0.078 12.6 1.1 0.16 11.6 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2414) CEP19 PF14933.1 ETO34286.1 - 0.1 12.8 3.2 7.6 6.8 0.4 2.3 2 0 0 2 2 2 0 CEP19-like protein Arb2 PF09757.4 ETO34286.1 - 0.13 11.7 2.9 0.26 10.6 0.3 2.1 2 0 0 2 2 2 0 Arb2 domain WD40 PF00400.27 ETO34287.1 - 4.9e-157 504.9 37.3 4.2e-13 48.6 0.0 15.3 15 0 0 15 15 15 15 WD domain, G-beta repeat NACHT PF05729.7 ETO34287.1 - 3.3e-09 36.6 0.0 6.5e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Cytochrom_D1 PF02239.11 ETO34287.1 - 9.1e-07 27.4 5.1 0.12 10.5 0.0 5.3 5 1 1 6 6 6 3 Cytochrome D1 heme domain Pentapeptide_4 PF13599.1 ETO34287.1 - 2.9e-06 26.9 0.6 2.9e-06 26.9 0.4 2.1 2 0 0 2 2 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETO34287.1 - 6.3e-05 22.1 1.0 0.00038 19.6 0.3 1.8 1 1 0 1 1 1 1 Pentapeptide repeats (8 copies) AAA_18 PF13238.1 ETO34287.1 - 0.00012 22.3 0.2 0.00012 22.3 0.1 3.7 3 1 1 4 4 3 1 AAA domain AAA_22 PF13401.1 ETO34287.1 - 0.00015 21.8 0.0 0.00045 20.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain Pentapeptide_3 PF13576.1 ETO34287.1 - 0.00024 20.9 0.1 0.00085 19.1 0.1 2.1 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA_17 PF13207.1 ETO34287.1 - 0.0013 19.5 1.0 0.014 16.2 0.0 3.1 2 0 0 2 2 2 1 AAA domain BetaGal_dom2 PF10435.4 ETO34287.1 - 0.0031 16.8 0.0 0.011 15.1 0.0 1.9 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 ATP_bind_2 PF03668.10 ETO34287.1 - 0.032 13.3 0.0 0.059 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop ATPase protein family CelD_N PF02927.9 ETO34287.1 - 0.039 14.2 0.0 1.7 8.9 0.0 3.5 4 0 0 4 4 3 0 N-terminal ig-like domain of cellulase PD40 PF07676.7 ETO34287.1 - 0.042 13.5 16.4 35 4.2 0.0 8.5 10 0 0 10 10 10 0 WD40-like Beta Propeller Repeat Flavokinase PF01687.12 ETO34288.1 - 9.5e-31 106.2 0.0 1.9e-29 102.1 0.0 2.0 2 0 0 2 2 2 1 Riboflavin kinase zf-RING_5 PF14634.1 ETO34289.1 - 0.0027 17.3 15.0 0.0043 16.7 10.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 ETO34289.1 - 0.0089 16.0 14.4 0.014 15.3 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) bZIP_C PF12498.3 ETO34289.1 - 0.023 15.9 2.0 0.043 15.0 0.5 2.1 2 0 0 2 2 2 0 Basic leucine-zipper C terminal zf-C3HC4 PF00097.20 ETO34289.1 - 0.029 14.0 15.4 0.05 13.2 10.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO34289.1 - 0.048 13.4 14.0 0.078 12.8 9.7 1.4 1 0 0 1 1 1 0 Ring finger domain Casc1 PF12366.3 ETO34289.1 - 0.071 12.5 2.4 0.55 9.6 0.2 2.2 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 DUF3496 PF12001.3 ETO34289.1 - 0.14 12.3 1.9 0.43 10.8 1.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) UPF0075 PF03702.9 ETO34290.1 - 5.9e-49 166.8 0.1 4.9e-32 111.2 0.0 2.1 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0075) Arf PF00025.16 ETO34291.1 - 3.5e-55 185.9 0.1 3.8e-55 185.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 ETO34291.1 - 4.6e-11 42.3 0.0 5.1e-11 42.2 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 ETO34291.1 - 3.7e-07 29.1 0.2 4.6e-07 28.8 0.1 1.3 1 1 0 1 1 1 1 G-protein alpha subunit GTP_EFTU PF00009.22 ETO34291.1 - 4.8e-06 26.1 0.0 6e-06 25.8 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 ETO34291.1 - 1.3e-05 24.4 0.0 1.6e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 ETO34291.1 - 0.00011 21.5 0.0 0.00012 21.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 ETO34291.1 - 0.00061 20.2 0.0 0.00096 19.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 ETO34291.1 - 0.01 15.7 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase KH_2 PF07650.12 ETO34291.1 - 0.1 12.1 0.0 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 KH domain OspE PF02471.12 ETO34292.1 - 0.042 13.7 2.3 0.77 9.6 0.1 2.7 2 0 0 2 2 2 0 Borrelia outer surface protein E DUF1343 PF07075.6 ETO34292.1 - 1.7 7.3 5.1 0.28 9.9 0.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1343) DUF2309 PF10070.4 ETO34293.1 - 0.6 8.1 9.7 0.58 8.1 6.1 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) Flu_NS2 PF00601.14 ETO34293.1 - 2.3 8.4 17.6 0.6 10.3 0.6 3.8 3 1 1 4 4 4 0 Influenza non-structural protein (NS2) Abi PF02517.11 ETO34295.1 - 7.8e-15 54.7 2.0 7.8e-15 54.7 1.4 2.6 2 1 0 2 2 2 1 CAAX protease self-immunity Phage_antitermQ PF06530.7 ETO34295.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Phage antitermination protein Q DUF3021 PF11457.3 ETO34295.1 - 5.9 6.7 10.3 1.8 8.4 3.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3021) CysG_dimeriser PF10414.4 ETO34299.1 - 0.074 12.5 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 0 Sirohaem synthase dimerisation region PPR_3 PF13812.1 ETO34300.1 - 7.7e-13 47.6 0.0 5.8e-07 29.2 0.0 3.9 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 ETO34300.1 - 9.4e-13 47.9 0.9 7e-11 41.9 0.2 3.0 2 1 1 3 3 3 2 PPR repeat family PPR PF01535.15 ETO34300.1 - 1.1e-11 43.8 0.6 6e-06 25.8 0.1 3.1 3 0 0 3 3 3 2 PPR repeat PPR_1 PF12854.2 ETO34300.1 - 1.1e-08 34.4 0.4 5.4e-05 22.5 0.0 2.6 3 0 0 3 3 3 2 PPR repeat ATP13 PF12921.2 ETO34300.1 - 0.049 12.9 0.4 4.1 6.7 0.1 2.4 1 1 1 2 2 2 0 Mitochondrial ATPase expression WD40 PF00400.27 ETO34301.1 - 1.6e-10 40.4 4.5 1.6e-07 30.9 0.3 3.8 3 1 1 4 4 4 2 WD domain, G-beta repeat DUF4221 PF13970.1 ETO34301.1 - 0.0027 17.0 0.4 0.0033 16.8 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4221) CblD PF07434.6 ETO34301.1 - 0.034 12.8 0.1 0.037 12.7 0.0 1.1 1 0 0 1 1 1 0 CblD like pilus biogenesis initiator WD40 PF00400.27 ETO34302.1 - 3.5e-31 105.9 9.9 4.6e-10 38.9 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO34302.1 - 5.5e-06 24.7 0.3 0.2 9.7 0.0 3.0 1 1 1 3 3 3 3 Nucleoporin Nup120/160 PRANC PF09372.5 ETO34303.1 - 0.0057 16.5 5.3 0.0057 16.5 3.7 2.3 1 1 2 3 3 3 1 PRANC domain DUF402 PF04167.8 ETO34304.1 - 0.041 13.7 0.1 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF402) BACK PF07707.10 ETO34304.1 - 0.1 12.4 0.5 0.21 11.4 0.2 1.7 2 0 0 2 2 2 0 BTB And C-terminal Kelch LRR_4 PF12799.2 ETO34305.1 - 4.2e-05 23.0 3.7 0.0063 16.1 0.1 3.4 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 ETO34305.1 - 0.00011 21.8 2.1 1.1 9.5 0.1 4.2 4 1 0 4 4 4 2 Leucine Rich repeat Pentapeptide PF00805.17 ETO34305.1 - 0.0017 17.5 0.3 0.0074 15.4 0.1 2.1 2 0 0 2 2 2 1 Pentapeptide repeats (8 copies) LRR_1 PF00560.28 ETO34305.1 - 0.005 16.6 2.5 11 6.5 0.2 4.2 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_8 PF13855.1 ETO34305.1 - 0.012 15.3 2.5 1.4 8.6 0.1 3.8 4 1 0 4 4 4 0 Leucine rich repeat LRR_7 PF13504.1 ETO34305.1 - 0.031 14.4 0.1 22 5.8 0.0 3.5 3 0 0 3 3 3 0 Leucine rich repeat LRR_2 PF07723.8 ETO34305.1 - 0.084 13.4 1.4 0.084 13.4 0.9 2.4 2 0 0 2 2 2 0 Leucine Rich Repeat PUB PF09409.5 ETO34306.1 - 1.9e-06 27.5 0.1 6e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 PUB domain UCH PF00443.24 ETO34308.1 - 4.5e-13 48.9 2.2 4.2e-12 45.7 0.2 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO34308.1 - 0.00052 19.5 1.6 0.028 13.8 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Glyco_hydro_88 PF07470.8 ETO34309.1 - 0.047 12.7 1.6 0.077 12.0 1.1 1.2 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 FliL PF03748.9 ETO34310.1 - 0.037 14.0 0.2 1.1 9.3 0.0 2.4 2 1 0 2 2 2 0 Flagellar basal body-associated protein FliL Bacillus_PapR PF05968.6 ETO34310.1 - 0.13 12.3 0.3 0.32 11.0 0.2 1.7 1 0 0 1 1 1 0 Bacillus PapR protein WD40 PF00400.27 ETO34311.1 - 5.2e-168 539.7 47.0 1.4e-12 46.9 0.0 16.3 16 0 0 16 16 16 15 WD domain, G-beta repeat Nup160 PF11715.3 ETO34311.1 - 7.4e-14 50.7 32.2 0.014 13.6 0.3 11.7 1 1 10 12 12 12 7 Nucleoporin Nup120/160 NACHT PF05729.7 ETO34311.1 - 4e-09 36.3 0.0 7.6e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO34311.1 - 5.2e-05 23.5 0.9 0.00022 21.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain Pentapeptide PF00805.17 ETO34311.1 - 6.3e-05 22.1 2.4 0.00027 20.1 1.7 1.7 1 1 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO34311.1 - 0.00052 19.7 0.2 0.0013 18.4 0.1 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA_22 PF13401.1 ETO34311.1 - 0.0007 19.7 0.0 0.0022 18.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain Resistin PF06954.6 ETO34311.1 - 0.004 17.3 0.2 59 4.0 0.0 5.7 4 1 1 5 5 5 0 Resistin Pentapeptide_3 PF13576.1 ETO34311.1 - 0.0053 16.6 0.1 0.013 15.3 0.1 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA_17 PF13207.1 ETO34311.1 - 0.0071 17.1 0.2 0.044 14.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 ETO34311.1 - 0.01 16.0 0.0 0.22 11.7 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PD40 PF07676.7 ETO34311.1 - 0.011 15.3 27.4 4.3 7.1 0.1 8.2 9 0 0 9 9 9 0 WD40-like Beta Propeller Repeat BLUF PF04940.7 ETO34311.1 - 0.26 11.0 3.3 12 5.6 0.0 5.1 7 0 0 7 7 6 0 Sensors of blue-light using FAD WD40 PF00400.27 ETO34313.1 - 8.4e-56 183.9 27.8 6.6e-13 47.9 0.2 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO34313.1 - 1.1e-11 43.6 4.9 0.00019 19.6 0.6 4.6 1 1 3 4 4 4 4 Nucleoporin Nup120/160 TPR_12 PF13424.1 ETO34317.1 - 3.5e-82 270.3 27.9 3.3e-17 62.1 0.6 6.1 2 2 4 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.23 ETO34317.1 - 1.7e-38 128.6 39.5 2.6e-05 23.6 0.1 10.3 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_11 PF13414.1 ETO34317.1 - 6.4e-38 128.2 25.9 3.8e-10 39.2 1.4 6.5 2 2 1 6 6 6 6 TPR repeat TPR_2 PF07719.12 ETO34317.1 - 9e-35 115.7 31.9 8.8e-05 22.1 0.2 10.3 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_7 PF13176.1 ETO34317.1 - 8.5e-34 112.6 8.6 0.0016 18.0 0.0 9.2 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_10 PF13374.1 ETO34317.1 - 4.2e-31 105.9 0.0 2.4e-05 24.1 0.0 9.0 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETO34317.1 - 9.1e-27 90.8 44.0 0.00031 20.3 0.1 9.7 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_17 PF13431.1 ETO34317.1 - 1.7e-14 52.7 9.8 0.56 10.5 0.1 9.1 9 1 1 10 10 9 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO34317.1 - 4e-14 52.8 0.0 0.11 13.1 0.0 6.2 5 1 2 7 7 7 2 Tetratricopeptide repeat Peptidase_C14 PF00656.17 ETO34317.1 - 3.2e-13 49.9 1.1 6.8e-13 48.8 0.6 1.7 2 0 0 2 2 2 1 Caspase domain TPR_19 PF14559.1 ETO34317.1 - 2.1e-09 37.5 1.8 0.92 9.8 0.0 6.0 5 2 2 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO34317.1 - 1.7e-08 34.3 0.0 27 5.7 0.0 7.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO34317.1 - 3.6e-08 33.3 4.8 10 6.8 0.0 7.6 7 0 0 7 7 7 0 Tetratricopeptide repeat MIT PF04212.13 ETO34317.1 - 2.6e-05 24.0 18.1 2.1 8.2 1.6 7.7 6 1 0 6 6 6 2 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 ETO34317.1 - 6.3e-05 23.0 29.7 0.054 13.6 1.3 6.4 3 2 4 7 7 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.4 ETO34317.1 - 0.0008 19.3 0.8 0.12 12.3 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Ten1_2 PF15490.1 ETO34317.1 - 0.0056 16.2 0.2 12 5.5 0.0 3.7 4 0 0 4 4 4 0 Telomere-capping, CST complex subunit SHNi-TPR PF10516.4 ETO34317.1 - 0.01 15.0 0.2 0.01 15.0 0.2 4.7 6 0 0 6 6 6 0 SHNi-TPR TPR_3 PF07720.7 ETO34317.1 - 0.011 15.5 7.9 5.4 6.9 0.1 5.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Claudin_2 PF13903.1 ETO34318.1 - 0.17 11.5 2.0 0.23 11.1 1.4 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Sod_Cu PF00080.15 ETO34319.1 - 0.00038 20.6 0.3 0.0024 18.0 0.2 1.9 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) NYAP_C PF15452.1 ETO34319.1 - 0.047 12.6 0.1 0.067 12.1 0.1 1.1 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter Acp26Ab PF05777.7 ETO34320.1 - 0.032 14.6 0.4 0.1 13.0 0.3 1.8 1 0 0 1 1 1 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) WD40 PF00400.27 ETO34321.1 - 5.4e-22 76.7 0.1 7.8e-10 38.2 0.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat DUF1899 PF08953.6 ETO34321.1 - 3.8e-10 39.2 0.0 6.9e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) Crystall_2 PF09076.5 ETO34321.1 - 0.0085 15.8 0.1 4.1 7.2 0.0 2.3 2 0 0 2 2 2 2 Beta/Gamma crystallin 7kD_coat PF02495.12 ETO34321.1 - 0.038 13.4 0.1 0.083 12.3 0.0 1.5 1 0 0 1 1 1 0 7kD viral coat protein Ank_2 PF12796.2 ETO34322.1 - 0.038 14.3 0.0 0.93 9.8 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Macro PF01661.16 ETO34322.1 - 0.084 12.7 0.3 8.1 6.3 0.0 2.3 1 1 1 2 2 2 0 Macro domain Tubulin PF00091.20 ETO34326.1 - 1.7e-55 188.1 0.3 3.2e-55 187.2 0.2 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO34326.1 - 3.7e-17 62.5 0.2 6.4e-17 61.7 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 ETO34326.1 - 9.9e-07 28.8 0.1 1.9e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Dna2 PF08696.6 ETO34327.1 - 1e-15 57.6 3.0 5.7e-15 55.1 0.5 2.6 1 1 1 2 2 2 1 DNA replication factor Dna2 WD40 PF00400.27 ETO34328.1 - 1.1e-65 215.2 23.6 3.5e-11 42.5 0.8 6.9 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO34328.1 - 3e-16 58.6 7.5 9.3e-05 20.7 0.2 6.0 2 2 4 6 6 6 6 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO34328.1 - 3e-05 22.9 17.1 0.58 8.8 0.1 5.5 2 1 3 5 5 5 4 Nup133 N terminal like HAD PF12710.2 ETO34328.1 - 0.17 11.9 4.3 2.2 8.3 0.0 3.2 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Peptidase_M50B PF13398.1 ETO34329.1 - 0.086 12.2 1.1 0.095 12.0 0.8 1.1 1 0 0 1 1 1 0 Peptidase M50B-like DUF4131 PF13567.1 ETO34329.1 - 0.78 9.1 3.0 1.1 8.6 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) SAM_2 PF07647.12 ETO34330.1 - 4.9e-12 45.5 0.1 6.1e-12 45.2 0.1 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO34330.1 - 6.4e-12 45.4 0.2 8.1e-12 45.1 0.1 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 ETO34330.1 - 0.0029 17.3 1.2 0.0065 16.2 0.8 1.7 1 1 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Pro_dh PF01619.13 ETO34330.1 - 0.039 12.9 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 Proline dehydrogenase KSR1-SAM PF13543.1 ETO34330.1 - 0.041 13.6 0.4 0.052 13.3 0.3 1.1 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 SAM_1 PF00536.25 ETO34331.1 - 1.6e-05 24.9 0.3 4.7e-05 23.4 0.2 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO34331.1 - 0.016 15.0 0.0 0.038 13.8 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) CorA PF01544.13 ETO34331.1 - 0.052 12.5 9.6 0.014 14.4 1.6 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein NEAT PF05031.7 ETO34332.1 - 0.55 10.2 3.9 1.8 8.5 0.3 2.8 3 0 0 3 3 3 0 Iron Transport-associated domain WD40 PF00400.27 ETO34333.1 - 1.7e-36 122.7 9.6 6.4e-13 48.0 0.0 4.3 4 1 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO34333.1 - 3.1e-07 28.9 0.1 0.0029 15.8 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO34333.1 - 0.0041 16.8 0.2 0.079 12.6 0.0 2.3 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A DUF3601 PF12208.3 ETO34333.1 - 0.031 14.1 0.0 2 8.3 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3601) Kinesin PF00225.18 ETO34334.1 - 2e-17 62.9 0.1 2e-17 62.9 0.0 3.3 2 1 1 3 3 3 1 Kinesin motor domain TPR_12 PF13424.1 ETO34335.1 - 3.3e-112 366.5 27.6 1.2e-18 66.7 0.3 8.1 6 2 2 8 8 8 8 Tetratricopeptide repeat TPR_11 PF13414.1 ETO34335.1 - 7.1e-64 211.3 46.7 2.5e-14 52.6 1.4 9.7 6 3 3 9 9 9 9 TPR repeat TPR_1 PF00515.23 ETO34335.1 - 1.6e-63 207.9 81.3 1.4e-08 33.9 0.5 14.6 14 1 0 14 14 14 12 Tetratricopeptide repeat TPR_10 PF13374.1 ETO34335.1 - 4.6e-60 197.9 0.0 1.3e-06 28.0 0.0 14.0 13 1 1 14 14 14 11 Tetratricopeptide repeat TPR_7 PF13176.1 ETO34335.1 - 1.6e-59 193.0 31.0 2.9e-08 32.8 0.1 13.4 12 1 1 13 13 13 11 Tetratricopeptide repeat TPR_2 PF07719.12 ETO34335.1 - 1e-51 168.7 56.5 2.4e-06 27.0 0.1 14.3 14 0 0 14 14 14 13 Tetratricopeptide repeat TPR_8 PF13181.1 ETO34335.1 - 2.4e-48 158.3 85.0 6e-06 25.6 0.4 14.3 14 0 0 14 14 14 11 Tetratricopeptide repeat TPR_17 PF13431.1 ETO34335.1 - 2.5e-27 92.7 27.6 0.00078 19.4 0.9 13.4 12 2 1 13 13 12 7 Tetratricopeptide repeat TPR_16 PF13432.1 ETO34335.1 - 8.9e-20 70.8 0.3 0.0046 17.5 0.1 9.3 5 4 6 11 11 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 ETO34335.1 - 5.7e-19 66.8 0.0 0.56 10.9 0.0 12.3 12 2 2 14 14 13 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO34335.1 - 2.1e-15 56.0 17.1 0.85 10.2 0.0 11.1 12 0 0 12 12 11 4 Tetratricopeptide repeat SNAP PF14938.1 ETO34335.1 - 2.6e-13 49.7 19.2 1.3e-06 27.7 0.1 4.9 3 3 1 4 4 4 4 Soluble NSF attachment protein, SNAP Apc3 PF12895.2 ETO34335.1 - 1.4e-09 37.9 34.3 0.0029 17.6 1.0 8.2 2 2 3 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO34335.1 - 4.3e-08 33.3 3.2 0.057 13.7 0.0 6.7 5 3 3 8 8 8 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO34335.1 - 3.9e-06 25.9 14.3 0.34 10.1 0.0 8.6 8 1 1 9 9 9 1 SHNi-TPR MIT PF04212.13 ETO34335.1 - 0.0004 20.1 37.2 0.43 10.5 0.2 9.9 9 2 1 10 10 10 2 MIT (microtubule interacting and transport) domain TPR_21 PF09976.4 ETO34335.1 - 0.0035 17.3 0.1 1.2 9.1 0.0 3.9 3 1 1 4 4 3 1 Tetratricopeptide repeat PPR PF01535.15 ETO34335.1 - 0.0059 16.5 0.2 0.0059 16.5 0.1 7.5 8 0 0 8 8 6 2 PPR repeat PPR_2 PF13041.1 ETO34335.1 - 0.0065 16.4 5.3 0.32 11.0 0.0 4.1 3 0 0 3 3 3 1 PPR repeat family POR PF01558.13 ETO34335.1 - 0.029 14.2 2.0 7.2 6.4 0.0 3.7 4 1 0 4 4 4 0 Pyruvate ferredoxin/flavodoxin oxidoreductase TPR_9 PF13371.1 ETO34335.1 - 0.045 13.6 0.8 5.6 6.8 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.7 ETO34335.1 - 4.2 8.1 28.2 8.7 7.1 0.3 9.1 11 0 0 11 11 10 0 Sel1 repeat MRP-L28 PF09812.4 ETO34335.1 - 9.6 6.0 11.5 0.45 10.3 2.2 2.8 3 0 0 3 3 3 0 Mitochondrial ribosomal protein L28 WD40 PF00400.27 ETO34336.1 - 7.9e-67 218.9 26.1 4.1e-12 45.4 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO34336.1 - 8.3e-12 44.0 9.0 0.084 10.9 0.4 5.8 1 1 4 5 5 5 5 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO34336.1 - 0.041 13.8 0.0 1.1 9.2 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3601) Peptidase_C14 PF00656.17 ETO34337.1 - 1.4e-05 24.8 0.0 1.6e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Caspase domain zf-TRAF PF02176.13 ETO34338.1 - 2.5e-05 24.5 3.3 2.5e-05 24.5 2.3 3.0 3 1 0 3 3 3 1 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 ETO34338.1 - 0.07 13.1 2.6 0.48 10.4 1.8 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.27 ETO34340.1 - 1.1e-53 177.2 26.4 7.1e-11 41.5 1.1 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO34340.1 - 2.1e-10 39.3 10.0 0.0032 15.6 0.3 5.0 3 2 2 5 5 5 5 Nucleoporin Nup120/160 Exo_endo_phos_2 PF14529.1 ETO34341.1 - 5.9e-13 48.4 0.2 1.6e-12 47.0 0.0 1.9 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 ETO34341.1 - 0.0084 16.0 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 ETO34343.1 - 4.8e-64 210.1 13.9 1.2e-13 50.3 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO34343.1 - 1.1e-09 38.2 0.1 0.0013 18.5 0.0 3.1 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO34343.1 - 1.2e-07 30.2 0.9 0.0016 16.6 0.3 2.8 1 1 0 2 2 2 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO34343.1 - 9.7e-05 20.8 0.1 0.0084 14.4 0.0 2.5 1 1 2 3 3 3 1 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO34343.1 - 0.00011 21.4 0.5 0.057 12.5 0.1 3.2 1 1 2 3 3 3 2 Neuroblastoma-amplified sequence, N terminal DPPIV_N PF00930.16 ETO34343.1 - 0.00039 19.1 0.2 0.66 8.5 0.0 4.2 1 1 4 5 5 5 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Resistin PF06954.6 ETO34343.1 - 0.00046 20.4 2.6 29 5.0 0.0 4.8 2 2 3 5 5 5 0 Resistin Coatomer_WDAD PF04053.9 ETO34343.1 - 0.00047 19.0 0.1 0.0075 15.1 0.0 2.4 1 1 1 2 2 2 1 Coatomer WD associated region PQQ_2 PF13360.1 ETO34343.1 - 0.0014 18.1 0.0 0.058 12.8 0.0 2.6 1 1 1 2 2 2 1 PQQ-like domain PD40 PF07676.7 ETO34343.1 - 0.0047 16.5 10.5 1.9 8.2 0.0 5.6 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat VID27 PF08553.5 ETO34343.1 - 0.018 13.2 0.1 0.13 10.5 0.0 1.9 2 0 0 2 2 2 0 VID27 cytoplasmic protein RicinB_lectin_2 PF14200.1 ETO34343.1 - 0.037 14.4 0.0 0.34 11.3 0.0 2.5 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like DUF1854 PF08909.6 ETO34343.1 - 0.11 12.0 0.2 7.9 6.0 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF1854) DUF2963 PF11178.3 ETO34343.1 - 2 7.8 4.9 7.4 6.0 0.0 4.0 5 1 0 5 5 5 0 Protein of unknown function (DUF2963) RVT_1 PF00078.22 ETO34344.1 - 2.9e-08 33.3 0.0 4.6e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FAM150 PF15129.1 ETO34344.1 - 0.017 14.9 0.6 0.045 13.6 0.4 1.7 1 0 0 1 1 1 0 FAM150 family DUF106 PF01956.11 ETO34344.1 - 0.22 11.0 0.9 0.34 10.4 0.7 1.5 1 0 0 1 1 1 0 Integral membrane protein DUF106 Mucin PF01456.12 ETO34347.1 - 1.3 8.7 12.0 2.8 7.7 8.3 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF600 PF04634.7 ETO34349.1 - 0.012 15.6 2.6 0.012 15.6 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF600 DUF402 PF04167.8 ETO34349.1 - 0.1 12.4 1.4 0.2 11.4 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF402) ACCA PF03255.9 ETO34349.1 - 9.1 5.8 9.6 5.6 6.5 3.9 2.5 2 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit SDP_N PF12278.3 ETO34350.1 - 0.0011 18.6 5.1 0.0017 18.0 3.6 1.3 1 0 0 1 1 1 1 Sex determination protein N terminal Ax_dynein_light PF10211.4 ETO34350.1 - 0.0079 16.0 5.9 0.011 15.5 4.1 1.2 1 0 0 1 1 1 1 Axonemal dynein light chain Prominin PF05478.6 ETO34350.1 - 0.06 10.8 8.4 0.07 10.6 5.8 1.0 1 0 0 1 1 1 0 Prominin DEAD PF00270.24 ETO34350.1 - 0.085 12.3 1.6 0.11 12.0 1.1 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase ARD PF03079.9 ETO34350.1 - 0.13 12.2 3.5 0.16 11.8 2.4 1.3 1 0 0 1 1 1 0 ARD/ARD' family zf-DNA_Pol PF08996.5 ETO34350.1 - 0.16 11.3 4.4 0.66 9.3 3.0 1.9 1 1 0 1 1 1 0 DNA Polymerase alpha zinc finger NID PF07292.8 ETO34350.1 - 0.22 11.5 3.8 0.31 11.0 1.1 2.3 2 1 1 3 3 3 0 Nmi/IFP 35 domain (NID) CBS PF00571.23 ETO34351.1 - 4.1e-07 29.6 0.0 0.00094 18.9 0.0 2.3 2 0 0 2 2 2 2 CBS domain zf-TRAF PF02176.13 ETO34352.1 - 4.5e-06 26.9 2.1 4.5e-06 26.9 1.5 2.6 2 1 1 3 3 3 1 TRAF-type zinc finger Sina PF03145.11 ETO34352.1 - 0.034 13.7 5.3 0.11 12.1 1.8 2.4 2 1 0 2 2 2 0 Seven in absentia protein family YojJ PF10372.4 ETO34352.1 - 0.054 13.3 0.4 0.16 11.8 0.3 1.8 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus zf-C3HC4_2 PF13923.1 ETO34352.1 - 0.55 10.3 8.8 0.21 11.6 0.8 3.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SlyX PF04102.7 ETO34352.1 - 7.2 7.0 8.5 3.7 8.0 0.2 2.7 2 0 0 2 2 2 0 SlyX WD40 PF00400.27 ETO34353.1 - 2.9e-40 134.7 14.7 4.5e-08 32.6 0.4 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 ETO34353.1 - 0.00029 20.5 0.0 0.11 12.2 0.0 3.0 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 ETO34353.1 - 0.0074 14.6 0.0 0.12 10.6 0.0 2.1 2 0 0 2 2 2 1 Cytochrome D1 heme domain GSDH PF07995.6 ETO34353.1 - 0.043 12.9 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Glucose / Sorbosone dehydrogenase Nup160 PF11715.3 ETO34353.1 - 0.045 11.8 0.5 0.35 8.9 0.0 2.4 3 0 0 3 3 3 0 Nucleoporin Nup120/160 GST_N PF02798.15 ETO34354.1 - 2.6e-11 43.5 0.0 7.3e-11 42.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 ETO34354.1 - 1.2e-06 28.3 0.1 3.6e-06 26.8 0.1 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 ETO34354.1 - 0.0033 17.8 0.6 0.0095 16.3 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETO34354.1 - 0.046 13.6 0.1 0.14 12.0 0.1 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Nup35_RRM_2 PF14605.1 ETO34354.1 - 0.11 12.2 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Pex14_N PF04695.8 ETO34355.1 - 0.037 14.0 4.5 0.067 13.2 3.1 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1675 PF07897.6 ETO34355.1 - 0.056 13.3 4.7 0.075 12.9 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Claudin_2 PF13903.1 ETO34355.1 - 0.14 11.8 1.0 0.28 10.8 0.7 1.4 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction SelP_N PF04592.9 ETO34355.1 - 0.49 9.7 11.2 0.8 9.0 7.8 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Menin PF05053.8 ETO34355.1 - 1 7.4 5.1 1.1 7.3 3.6 1.1 1 0 0 1 1 1 0 Menin RP-C_C PF11800.3 ETO34355.1 - 1.2 8.8 4.3 1.5 8.4 3.0 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region WD40 PF00400.27 ETO34356.1 - 1.5e-58 192.7 19.6 6.5e-11 41.6 0.5 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO34356.1 - 2.6e-07 29.1 2.7 0.13 10.3 0.0 4.8 2 1 2 5 5 5 4 Nucleoporin Nup120/160 DUF3931 PF13082.1 ETO34356.1 - 0.1 12.4 3.3 13 5.7 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3931) ELL PF10390.4 ETO34357.1 - 0.016 14.4 0.6 0.016 14.4 0.4 1.1 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL Pyr_redox_2 PF07992.9 ETO34358.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Got1 PF04178.7 ETO34358.1 - 2.8 8.0 7.7 0.17 11.9 0.8 2.1 2 0 0 2 2 2 0 Got1/Sft2-like family TRAP_alpha PF03896.11 ETO34359.1 - 0.031 13.2 10.2 0.052 12.5 7.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit MIP-T3 PF10243.4 ETO34359.1 - 0.038 12.4 37.8 0.052 12.0 26.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Mucin PF01456.12 ETO34359.1 - 0.16 11.7 25.8 0.87 9.3 18.1 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein SSP160 PF06933.6 ETO34359.1 - 0.87 7.4 19.4 1.2 6.9 13.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Peptidase_S64 PF08192.6 ETO34359.1 - 1.1 7.5 16.3 1.5 7.0 11.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF605 PF04652.11 ETO34359.1 - 6 6.1 21.3 11 5.3 14.7 1.3 1 0 0 1 1 1 0 Vta1 like Utp14 PF04615.8 ETO34359.1 - 7.5 4.5 34.4 11 4.0 23.8 1.2 1 0 0 1 1 1 0 Utp14 protein TLD PF07534.11 ETO34360.1 - 8.3e-16 58.2 2.1 2.4e-15 56.7 1.5 1.7 1 0 0 1 1 1 1 TLD Rad9 PF04139.8 ETO34360.1 - 0.017 14.2 1.7 0.027 13.5 1.2 1.3 1 0 0 1 1 1 0 Rad9 TUG-UBL1 PF11470.3 ETO34360.1 - 0.11 12.4 0.9 0.28 11.1 0.4 1.9 1 1 1 2 2 2 0 GLUT4 regulating protein TUG Rep_fac-A_C PF08646.5 ETO34361.1 - 7.1e-16 58.2 0.0 3.1e-15 56.1 0.0 1.9 2 0 0 2 2 2 1 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 ETO34361.1 - 0.037 13.8 0.0 0.13 12.1 0.0 2.0 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain WD40 PF00400.27 ETO34362.1 - 2.2e-15 55.8 8.0 9e-05 22.2 0.8 4.5 3 1 1 4 4 4 4 WD domain, G-beta repeat DUF2116 PF09889.4 ETO34362.1 - 4.4 7.1 9.1 13 5.6 0.6 2.6 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Clathrin PF00637.15 ETO34365.1 - 1.5e-07 31.0 0.0 5e-05 22.9 0.0 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS 60KD_IMP PF02096.15 ETO34365.1 - 0.016 14.8 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 60Kd inner membrane protein DUF4443 PF14544.1 ETO34365.1 - 0.14 12.0 0.1 2.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4443) zf-RING_2 PF13639.1 ETO34365.1 - 0.34 10.7 6.7 0.22 11.3 1.7 2.4 2 0 0 2 2 2 0 Ring finger domain STAG PF08514.6 ETO34366.1 - 0.014 15.1 1.6 2.3 7.9 0.1 2.5 2 0 0 2 2 2 0 STAG domain Phage_G PF02306.10 ETO34366.1 - 0.1 12.1 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Major spike protein (G protein) Rad60-SLD PF11976.3 ETO34367.1 - 0.00044 19.8 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Baculo_ODV-E27 PF05314.6 ETO34367.1 - 0.052 12.6 0.0 0.071 12.1 0.0 1.1 1 0 0 1 1 1 0 Baculovirus occlusion-derived virus envelope protein EC27 ubiquitin PF00240.18 ETO34367.1 - 0.061 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family MBT PF02820.13 ETO34368.1 - 0.00091 19.1 0.1 0.0055 16.6 0.0 2.0 2 0 0 2 2 2 1 mbt repeat BNR_2 PF13088.1 ETO34368.1 - 0.0046 16.2 0.6 0.0065 15.8 0.4 1.2 1 0 0 1 1 1 1 BNR repeat-like domain Tudor-knot PF11717.3 ETO34368.1 - 0.088 12.5 1.1 0.24 11.1 0.8 1.8 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain PAP_assoc PF03828.14 ETO34369.1 - 7.1e-13 48.3 2.0 1.3e-12 47.5 0.2 2.4 2 0 0 2 2 2 1 Cid1 family poly A polymerase DUF2363 PF10155.4 ETO34370.1 - 1.7e-33 115.2 6.2 1.7e-33 115.2 4.3 1.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2363) MAPKK1_Int PF08923.5 ETO34371.1 - 3.1e-16 59.0 0.9 4e-16 58.6 0.6 1.1 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting Phageshock_PspD PF09584.5 ETO34371.1 - 0.0069 16.0 0.2 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 Phage shock protein PspD (Phageshock_PspD) AnfO_nitrog PF09582.5 ETO34371.1 - 0.061 12.4 0.3 0.091 11.8 0.2 1.3 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) Histidinol_dh PF00815.15 ETO34371.1 - 0.094 11.3 0.3 0.11 11.0 0.2 1.2 1 0 0 1 1 1 0 Histidinol dehydrogenase DUF4179 PF13786.1 ETO34372.1 - 0.014 15.5 0.3 0.056 13.6 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) DUF2306 PF10067.4 ETO34372.1 - 0.32 11.1 0.1 0.32 11.1 0.1 4.3 4 1 1 5 5 5 0 Predicted membrane protein (DUF2306) DUF202 PF02656.10 ETO34372.1 - 6.7 7.0 7.2 21 5.4 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF202) DUF912 PF06024.7 ETO34373.1 - 0.049 13.6 0.6 0.068 13.2 0.4 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Use1 PF09753.4 ETO34374.1 - 0.023 14.1 0.8 0.04 13.3 0.6 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 zf-DHHC PF01529.15 ETO34375.1 - 4.3e-08 32.7 5.0 5.5e-08 32.3 3.5 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase Glyco_transf_25 PF01755.12 ETO34376.1 - 0.0065 16.1 0.1 0.0069 16.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) MRP-L28 PF09812.4 ETO34377.1 - 0.037 13.8 0.2 0.087 12.6 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 WD40 PF00400.27 ETO34378.1 - 4e-20 70.8 0.6 1.5e-12 46.8 0.1 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF3291 PF11695.3 ETO34378.1 - 0.013 14.8 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3291) PD40 PF07676.7 ETO34378.1 - 0.044 13.4 0.1 9.9 5.9 0.0 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat PhaP_Bmeg PF09602.5 ETO34379.1 - 0.044 13.6 5.8 0.065 13.0 4.0 1.3 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) NAP PF00956.13 ETO34379.1 - 0.072 12.2 4.5 0.1 11.6 3.1 1.2 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) Atg14 PF10186.4 ETO34379.1 - 1.4 7.7 15.0 1.5 7.7 10.4 1.2 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ax_dynein_light PF10211.4 ETO34379.1 - 1.5 8.6 13.7 0.68 9.7 4.3 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain DUF4407 PF14362.1 ETO34379.1 - 2 7.2 7.3 3.3 6.5 5.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF342 PF03961.8 ETO34379.1 - 2.2 6.6 6.6 2.7 6.2 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Seryl_tRNA_N PF02403.17 ETO34379.1 - 3.9 7.5 9.2 11 6.0 4.7 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3373 PF11853.3 ETO34379.1 - 5.2 5.4 6.5 10 4.5 4.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) V_ATPase_I PF01496.14 ETO34379.1 - 6.1 4.5 9.3 3.9 5.2 3.8 1.8 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family HemX PF04375.9 ETO34379.1 - 6.9 5.1 9.5 12 4.3 6.6 1.4 1 0 0 1 1 1 0 HemX MBA1 PF07961.6 ETO34380.1 - 0.09 11.6 0.7 0.66 8.7 0.5 1.9 1 1 0 1 1 1 0 MBA1-like protein LRR_4 PF12799.2 ETO34381.1 - 0.00035 20.1 5.9 0.0044 16.6 0.0 4.1 5 1 0 5 5 5 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO34381.1 - 0.0062 16.2 6.7 4.6 7.0 0.2 4.5 4 1 1 5 5 5 2 Leucine rich repeat DUF383 PF04063.9 ETO34381.1 - 0.019 14.5 0.3 0.035 13.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF383) LRR_7 PF13504.1 ETO34381.1 - 0.093 12.9 2.5 52 4.7 0.0 4.9 5 0 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 ETO34381.1 - 0.26 11.4 6.6 1.1e+02 3.3 0.0 5.3 6 1 0 6 6 6 0 Leucine Rich repeat LRR_1 PF00560.28 ETO34381.1 - 1.5 9.1 6.9 42 4.7 0.1 5.0 5 0 0 5 5 5 0 Leucine Rich Repeat AAA_18 PF13238.1 ETO34382.1 - 0.36 11.1 3.5 0.3 11.3 0.8 2.0 1 1 1 2 2 2 0 AAA domain CAP_GLY PF01302.20 ETO34383.1 - 4.8e-14 51.8 0.2 9.6e-14 50.8 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain PMD PF10536.4 ETO34383.1 - 0.035 13.0 0.2 0.073 12.0 0.2 1.5 1 0 0 1 1 1 0 Plant mobile domain DHDPS PF00701.17 ETO34384.1 - 1.6e-15 56.4 0.0 2.8e-15 55.6 0.0 1.3 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family F_bP_aldolase PF01116.15 ETO34384.1 - 0.036 13.1 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II DUF2400 PF09674.5 ETO34385.1 - 0.0061 16.2 0.7 0.0082 15.8 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2400) Lipoprotein_X PF03305.8 ETO34385.1 - 0.0091 15.3 5.3 0.014 14.8 3.7 1.3 1 0 0 1 1 1 1 Mycoplasma MG185/MG260 protein AUX_IAA PF02309.11 ETO34385.1 - 0.012 15.4 0.8 0.016 14.9 0.6 1.2 1 0 0 1 1 1 0 AUX/IAA family DUF2828 PF11443.3 ETO34385.1 - 0.019 13.1 4.0 0.023 12.9 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Presenilin PF01080.12 ETO34385.1 - 0.021 13.6 2.5 0.026 13.3 1.7 1.1 1 0 0 1 1 1 0 Presenilin MMR1 PF08505.5 ETO34385.1 - 0.029 14.4 7.3 0.026 14.5 4.3 1.5 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Neur_chan_memb PF02932.11 ETO34385.1 - 0.069 13.0 1.4 0.079 12.8 1.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region IncA PF04156.9 ETO34385.1 - 0.075 12.6 3.2 0.089 12.3 2.2 1.2 1 0 0 1 1 1 0 IncA protein Zip PF02535.17 ETO34385.1 - 0.082 11.9 1.0 0.096 11.6 0.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4175 PF13779.1 ETO34385.1 - 0.22 9.1 12.7 0.27 8.8 8.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Sec62 PF03839.11 ETO34385.1 - 0.31 10.4 3.1 0.49 9.7 2.2 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Metaviral_G PF09595.5 ETO34385.1 - 0.36 10.4 10.4 0.24 10.9 4.4 2.0 2 0 0 2 2 2 0 Metaviral_G glycoprotein Cnd1 PF12717.2 ETO34387.1 - 2.3e-05 24.3 4.9 0.025 14.4 0.2 2.2 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 ETO34387.1 - 0.00012 22.2 0.0 0.00065 19.9 0.0 2.1 1 1 1 2 2 2 1 HEAT repeats HEAT_EZ PF13513.1 ETO34387.1 - 0.00015 22.1 0.0 0.13 12.8 0.0 3.6 2 1 1 3 3 3 1 HEAT-like repeat CLASP_N PF12348.3 ETO34387.1 - 0.00031 20.1 1.0 0.00096 18.5 0.3 1.9 2 0 0 2 2 2 1 CLASP N terminal DUF1758 PF05585.7 ETO34387.1 - 0.00069 19.2 0.2 0.0013 18.3 0.2 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) DNA_alkylation PF08713.6 ETO34387.1 - 0.0015 18.1 1.4 0.032 13.7 0.4 2.1 1 1 1 2 2 2 1 DNA alkylation repair enzyme HEAT PF02985.17 ETO34387.1 - 0.0048 16.8 0.1 0.11 12.5 0.0 3.0 3 0 0 3 3 2 1 HEAT repeat MA3 PF02847.12 ETO34387.1 - 0.0051 16.5 2.0 0.077 12.7 0.1 2.6 1 1 2 3 3 3 1 MA3 domain ENTH PF01417.15 ETO34387.1 - 0.012 15.4 1.5 0.81 9.5 0.9 2.6 1 1 0 1 1 1 0 ENTH domain Imm42 PF15601.1 ETO34387.1 - 0.072 12.5 0.3 5.7 6.3 0.0 3.1 2 1 2 4 4 4 0 Immunity protein 42 DUF445 PF04286.7 ETO34387.1 - 0.13 11.8 1.7 0.38 10.2 1.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF445) N_Asn_amidohyd PF14736.1 ETO34387.1 - 0.18 10.6 2.0 0.35 9.6 0.1 1.9 1 1 2 3 3 2 0 Protein N-terminal asparagine amidohydrolase RNA_binding PF01877.12 ETO34387.1 - 0.52 10.3 3.5 0.77 9.7 0.4 2.6 2 1 1 3 3 3 0 RNA binding DUF1672 PF07901.6 ETO34387.1 - 2.5 6.9 9.4 3.8 6.4 6.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1672) TetR_C_8 PF14278.1 ETO34388.1 - 0.18 12.2 5.8 9.2 6.7 0.4 3.0 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region CENP-F_leu_zip PF10473.4 ETO34389.1 - 0.00054 19.8 18.7 0.00054 19.8 13.0 5.7 2 2 1 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 ETO34389.1 - 0.003 16.7 30.9 0.091 11.9 0.2 4.5 1 1 2 4 4 4 3 Reovirus sigma C capsid protein DUF948 PF06103.6 ETO34389.1 - 0.024 14.4 64.1 0.49 10.2 1.1 7.9 4 2 4 8 8 8 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 ETO34389.1 - 0.51 9.8 126.6 0.097 12.2 13.1 5.3 1 1 3 5 5 5 0 IncA protein TMF_DNA_bd PF12329.3 ETO34389.1 - 0.54 10.0 146.1 0.068 12.9 9.1 11.6 5 4 5 11 11 11 0 TATA element modulatory factor 1 DNA binding GAS PF13851.1 ETO34389.1 - 0.96 8.6 128.4 0.37 9.9 13.2 6.3 1 1 5 6 6 6 0 Growth-arrest specific micro-tubule binding AAA_13 PF13166.1 ETO34389.1 - 9 4.6 99.4 0.3 9.4 16.9 3.7 1 1 2 3 3 3 0 AAA domain WEMBL PF05701.6 ETO34389.1 - 9.7 4.5 112.8 4 5.7 38.3 2.9 2 1 0 2 2 2 0 Weak chloroplast movement under blue light DNA_ligase_OB_2 PF14743.1 ETO34392.1 - 0.062 12.9 0.2 0.16 11.6 0.0 1.8 2 1 0 2 2 2 0 DNA ligase OB-like domain PRTP PF01366.13 ETO34392.1 - 0.12 10.3 5.3 0.12 10.2 3.7 1.0 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Transcrip_reg PF01709.15 ETO34392.1 - 0.43 9.6 8.8 0.53 9.3 6.1 1.1 1 0 0 1 1 1 0 Transcriptional regulator Ribosomal_L37 PF08561.5 ETO34393.1 - 3.8e-05 23.1 0.7 3.8e-05 23.1 0.5 2.3 2 1 0 2 2 2 1 Mitochondrial ribosomal protein L37 Ribosomal_S2 PF00318.15 ETO34394.1 - 1.2e-36 125.9 0.0 2.6e-36 124.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S2 Dynamin_N PF00350.18 ETO34395.1 - 0.0037 17.1 1.1 0.0037 17.1 0.7 3.1 3 1 0 3 3 3 1 Dynamin family Toxin_39 PF15500.1 ETO34396.1 - 0.053 13.6 3.6 0.33 11.0 0.1 2.2 2 1 0 2 2 2 0 Putative RNase-like toxin RPM2 PF08579.6 ETO34396.1 - 0.077 13.1 4.1 0.45 10.6 0.2 2.2 1 1 1 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) Rot1 PF10681.4 ETO34396.1 - 0.082 12.2 3.3 0.097 11.9 2.3 1.2 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal Phage_lambd_GpG PF06894.6 ETO34396.1 - 0.082 12.5 1.6 0.13 11.8 1.1 1.5 1 1 0 1 1 1 0 Bacteriophage lambda minor tail protein (GpG) Pap_E4 PF02711.9 ETO34396.1 - 0.15 12.8 0.3 0.15 12.8 0.2 1.8 1 1 1 2 2 2 0 E4 protein Beach PF02138.13 ETO34396.1 - 0.16 11.3 4.8 0.18 11.1 3.3 1.0 1 0 0 1 1 1 0 Beige/BEACH domain Acetyltransf_11 PF13720.1 ETO34396.1 - 0.35 11.1 4.3 0.28 11.4 1.0 2.0 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 ATP-synt_G PF04718.10 ETO34396.1 - 1.1 9.9 4.4 0.89 10.2 1.4 1.8 1 1 1 2 2 2 0 Mitochondrial ATP synthase g subunit CDC37_N PF03234.9 ETO34396.1 - 2.8 8.2 12.5 3.3 8.0 8.7 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Occludin_ELL PF07303.8 ETO34396.1 - 4.4 8.1 14.7 4.5 8.0 2.2 2.1 1 1 1 2 2 2 0 Occludin homology domain Kelch_4 PF13418.1 ETO34397.1 - 8.9e-08 31.7 1.5 6.2e-05 22.6 0.1 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO34397.1 - 3.7e-06 26.8 4.7 7.8e-05 22.6 0.2 3.3 2 1 1 3 3 3 1 Kelch motif Kelch_1 PF01344.20 ETO34397.1 - 0.011 15.2 10.3 0.048 13.2 0.9 4.0 4 1 0 4 4 4 0 Kelch motif Kelch_3 PF13415.1 ETO34397.1 - 0.025 14.7 0.0 0.025 14.7 0.0 2.3 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO34397.1 - 0.034 14.1 5.6 0.087 12.8 0.7 3.1 3 1 1 4 4 4 0 Kelch motif Kelch_2 PF07646.10 ETO34397.1 - 1.2 9.0 4.8 6.8 6.6 0.2 3.3 3 0 0 3 3 3 0 Kelch motif WD40 PF00400.27 ETO34398.1 - 6.8e-42 139.8 8.1 8.1e-14 50.8 0.2 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO34398.1 - 3.1e-06 25.6 0.1 0.0071 14.5 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO34398.1 - 8.8e-05 20.9 0.0 0.00095 17.5 0.0 2.0 1 1 1 2 2 2 1 Cytochrome D1 heme domain PD40 PF07676.7 ETO34398.1 - 0.0014 18.2 2.1 6.1 6.6 0.0 3.8 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO34398.1 - 0.0028 16.4 0.8 0.065 11.9 0.4 2.2 1 1 0 1 1 1 1 Nup133 N terminal like TFIIIC_delta PF12657.2 ETO34398.1 - 0.047 13.3 1.7 0.12 12.1 0.2 2.1 1 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term Proteasome_A_N PF10584.4 ETO34398.1 - 2.1 7.7 5.7 6.4 6.1 0.0 3.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature HSP70 PF00012.15 ETO34399.1 - 2.1e-222 739.3 8.7 6.2e-222 737.7 6.1 1.6 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 ETO34399.1 - 1.1e-12 47.2 0.0 1.6e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Hydantoinase_A PF01968.13 ETO34399.1 - 0.016 14.3 0.9 0.033 13.2 0.1 1.8 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase NPV_P10 PF05531.7 ETO34399.1 - 0.73 10.1 6.0 0.92 9.8 0.1 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1319 PF07028.6 ETO34399.1 - 1 9.5 7.2 0.65 10.1 0.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1319) DUF2508 PF10704.4 ETO34399.1 - 4.4 7.5 7.8 0.48 10.6 0.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2508) NACHT PF05729.7 ETO34400.1 - 1.1e-16 60.8 0.0 2.7e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Sigma54_activ_2 PF14532.1 ETO34400.1 - 0.00019 21.5 0.0 0.0099 15.9 0.0 2.5 1 1 0 1 1 1 1 Sigma-54 interaction domain NB-ARC PF00931.17 ETO34400.1 - 0.00075 18.4 0.1 0.00075 18.4 0.1 2.0 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.1 ETO34400.1 - 0.0025 17.9 0.3 0.037 14.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETO34400.1 - 0.0094 16.2 0.0 0.0094 16.2 0.0 3.8 2 2 1 3 3 3 1 AAA domain AAA_25 PF13481.1 ETO34400.1 - 0.02 14.3 0.0 0.2 11.0 0.0 2.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 ETO34400.1 - 0.022 15.0 0.0 0.098 12.9 0.0 2.1 2 0 0 2 2 2 0 ABC transporter FtsK_SpoIIIE PF01580.13 ETO34400.1 - 0.027 13.9 0.0 0.054 12.9 0.0 1.5 1 1 0 1 1 1 0 FtsK/SpoIIIE family SMC_N PF02463.14 ETO34400.1 - 0.028 13.6 0.0 0.15 11.2 0.0 2.2 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 ETO34400.1 - 0.06 13.3 0.0 0.23 11.4 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.12 ETO34400.1 - 0.074 12.8 2.5 0.28 10.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_30 PF13604.1 ETO34400.1 - 0.15 11.5 0.0 0.38 10.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain HEAT_2 PF13646.1 ETO34401.1 - 2.5e-21 75.7 0.0 6.9e-06 26.2 0.0 7.7 4 3 5 9 9 8 7 HEAT repeats HEAT PF02985.17 ETO34401.1 - 1.2e-19 68.5 0.6 1.9 8.8 0.0 11.5 11 0 0 11 11 11 4 HEAT repeat HEAT_EZ PF13513.1 ETO34401.1 - 2.6e-10 40.4 0.0 0.2 12.2 0.0 8.5 6 2 2 8 8 8 1 HEAT-like repeat Cnd1 PF12717.2 ETO34401.1 - 1.3e-07 31.6 18.6 0.00088 19.1 2.4 4.9 3 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 ETO34401.1 - 2.8e-06 27.6 6.6 0.054 13.8 0.1 4.9 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region Ank_2 PF12796.2 ETO34401.1 - 2.2e-05 24.7 0.0 0.00013 22.2 0.0 2.4 2 0 0 2 2 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO34401.1 - 2.7e-05 24.2 0.0 0.00011 22.3 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO34401.1 - 7.1e-05 22.6 0.0 0.0028 17.7 0.0 3.5 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.25 ETO34401.1 - 8.2e-05 22.2 0.0 0.0004 20.0 0.0 2.3 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.1 ETO34401.1 - 0.00035 21.0 0.0 0.0014 19.1 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) HEAT_PBS PF03130.11 ETO34401.1 - 0.44 11.1 2.2 1.6e+02 3.2 0.0 5.5 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat DUF1104 PF06518.6 ETO34402.1 - 0.037 14.1 1.2 0.17 12.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) Myb_DNA-bind_6 PF13921.1 ETO34404.1 - 1.3e-09 38.0 0.4 9.7e-05 22.4 0.1 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 ETO34404.1 - 5.8e-06 26.2 0.1 0.00093 19.2 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain FliT PF05400.8 ETO34404.1 - 0.084 13.2 1.6 0.18 12.2 1.1 1.5 1 0 0 1 1 1 0 Flagellar protein FliT zf-TRAF PF02176.13 ETO34405.1 - 4.3e-05 23.8 2.5 4.3e-05 23.8 1.7 2.8 3 0 0 3 3 3 1 TRAF-type zinc finger V-ATPase_G PF03179.10 ETO34405.1 - 0.097 12.9 8.2 0.19 12.0 5.0 2.0 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Exonuc_VII_L PF02601.10 ETO34405.1 - 3 6.9 11.8 5.2 6.1 8.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tup_N PF08581.5 ETO34405.1 - 3.5 7.8 17.5 1.2 9.4 2.1 2.8 1 1 0 2 2 2 0 Tup N-terminal PhoU PF01895.14 ETO34405.1 - 4.2 7.8 8.1 0.84 10.1 0.9 2.5 1 1 1 2 2 2 0 PhoU domain WD40 PF00400.27 ETO34406.1 - 2.6e-14 52.4 5.1 5.2e-07 29.2 0.0 3.5 3 1 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO34406.1 - 0.037 12.1 0.3 0.22 9.6 0.2 1.9 1 1 0 1 1 1 0 Nucleoporin Nup120/160 EBA-175_VI PF11556.3 ETO34407.1 - 0.034 14.2 2.6 0.052 13.6 1.8 1.2 1 0 0 1 1 1 0 Erythrocyte binding antigen 175 zf-C3HC4_2 PF13923.1 ETO34407.1 - 0.087 12.8 3.4 1.8 8.6 2.2 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO34407.1 - 0.32 10.8 7.0 0.79 9.6 2.2 2.7 2 1 1 3 3 3 0 Ring finger domain zf-P11 PF03854.9 ETO34407.1 - 0.68 9.4 3.1 12 5.5 0.0 2.4 2 0 0 2 2 2 0 P-11 zinc finger zf-C3HC4 PF00097.20 ETO34407.1 - 1.8 8.2 6.0 2.6 7.7 0.1 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CAP_GLY PF01302.20 ETO34408.1 - 2.8e-06 26.9 0.0 4.9e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF4297 PF14130.1 ETO34408.1 - 0.69 9.8 4.4 0.88 9.4 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4297) BEN PF10523.4 ETO34409.1 - 0.57 10.2 2.7 1.3 9.0 0.8 2.2 1 1 1 2 2 2 0 BEN domain WD40 PF00400.27 ETO34410.1 - 1.7e-10 40.3 0.9 2.2e-05 24.1 0.1 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat CSD PF00313.17 ETO34411.1 - 0.00053 19.7 0.7 0.83 9.4 0.0 2.9 2 1 1 3 3 3 2 'Cold-shock' DNA-binding domain DUF2223 PF09985.4 ETO34412.1 - 0.036 13.3 0.1 0.071 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2223) bZIP_1 PF00170.16 ETO34412.1 - 1.8 8.5 16.8 2 8.4 0.9 2.9 2 1 0 2 2 2 0 bZIP transcription factor Cob_adeno_trans PF01923.13 ETO34412.1 - 8.3 6.1 9.8 4.2 7.1 1.2 2.3 2 0 0 2 2 2 0 Cobalamin adenosyltransferase zf-C3HC4_3 PF13920.1 ETO34413.1 - 6.9e-12 44.8 12.4 1.1e-11 44.1 8.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO34413.1 - 0.0015 18.4 16.0 0.0029 17.5 11.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-DHHC PF01529.15 ETO34413.1 - 0.008 15.5 7.9 0.02 14.2 5.4 1.7 1 0 0 1 1 1 1 DHHC palmitoyltransferase zf-RING_5 PF14634.1 ETO34413.1 - 0.022 14.4 14.0 0.039 13.6 9.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 ETO34413.1 - 0.042 13.6 14.5 0.094 12.5 10.1 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 ETO34413.1 - 0.13 11.8 16.7 0.29 10.8 11.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.27 ETO34414.1 - 3.8e-12 45.5 3.2 9.8e-08 31.5 0.3 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO34414.1 - 0.0001 20.6 0.1 0.00011 20.5 0.1 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 WD40 PF00400.27 ETO34415.1 - 8.4e-135 434.4 42.7 2.3e-11 43.1 0.2 16.6 16 0 0 16 16 16 16 WD domain, G-beta repeat NACHT PF05729.7 ETO34415.1 - 6e-09 35.7 0.0 1.3e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PQQ_2 PF13360.1 ETO34415.1 - 1.4e-06 27.9 3.3 0.064 12.7 0.0 4.9 3 2 0 3 3 3 2 PQQ-like domain AAA_22 PF13401.1 ETO34415.1 - 8.4e-05 22.7 0.0 0.00024 21.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain Pentapeptide PF00805.17 ETO34415.1 - 9.2e-05 21.5 1.5 0.00019 20.5 1.1 1.4 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) AAA_18 PF13238.1 ETO34415.1 - 0.00021 21.5 0.0 0.00021 21.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 ETO34415.1 - 0.0012 19.6 3.0 0.0048 17.6 0.0 3.4 4 0 0 4 4 4 1 AAA domain Pentapeptide_4 PF13599.1 ETO34415.1 - 0.0013 18.4 1.4 0.0037 17.0 1.0 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 ETO34415.1 - 0.023 14.5 2.2 0.033 14.0 0.1 2.3 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) PD40 PF07676.7 ETO34415.1 - 0.29 10.8 20.3 8 6.2 0.0 8.4 11 0 0 11 11 11 0 WD40-like Beta Propeller Repeat Mucin PF01456.12 ETO34416.1 - 0.0066 16.2 11.0 0.0066 16.2 7.6 1.6 2 0 0 2 2 2 1 Mucin-like glycoprotein Gly-zipper_Omp PF13488.1 ETO34416.1 - 0.024 14.2 11.1 0.66 9.6 1.6 2.5 2 0 0 2 2 2 0 Glycine zipper DUF3439 PF11921.3 ETO34416.1 - 0.2 11.4 9.8 0.43 10.3 6.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 ETO34416.1 - 1.6 6.5 14.3 3.2 5.6 9.9 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SAPS PF04499.10 ETO34417.1 - 1.2 7.7 6.6 1.2 7.7 4.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Tim54 PF11711.3 ETO34417.1 - 4.1 5.8 6.7 5 5.6 4.7 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF1764 PF08576.5 ETO34417.1 - 9 7.1 12.2 19 6.1 8.5 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Racemase_4 PF13615.1 ETO34418.1 - 0.061 13.5 2.0 1.1 9.4 0.2 2.3 2 0 0 2 2 2 0 Putative alanine racemase ubiquitin PF00240.18 ETO34421.1 - 0.00038 19.8 0.0 0.0008 18.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Cytomega_TRL10 PF06084.6 ETO34421.1 - 0.11 12.2 0.0 0.32 10.7 0.0 1.7 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein Telomere_Sde2 PF13019.1 ETO34421.1 - 0.13 11.9 0.4 0.86 9.2 0.0 2.1 2 0 0 2 2 2 0 Telomere stability and silencing Proteasome PF00227.21 ETO34422.1 - 1.1e-13 50.9 0.1 1.1e-12 47.6 0.1 1.9 1 1 0 1 1 1 1 Proteasome subunit Ribosomal_S2 PF00318.15 ETO34423.1 - 2.4e-11 43.2 0.0 3.1e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S2 zf-C3HC4_4 PF15227.1 ETO34424.1 - 0.028 14.2 0.5 0.043 13.6 0.4 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FGGY_C PF02782.11 ETO34426.1 - 8e-24 84.3 0.0 1.1e-23 83.8 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 ETO34427.1 - 5e-11 42.3 0.0 7.3e-08 32.0 0.0 2.6 3 0 0 3 3 3 2 FGGY family of carbohydrate kinases, N-terminal domain DUF1574 PF07611.6 ETO34428.1 - 0.069 12.0 0.4 0.074 11.9 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) SpoIISB_antitox PF14185.1 ETO34428.1 - 0.75 9.5 5.6 1.4 8.6 3.9 1.5 1 0 0 1 1 1 0 Antitoxin SpoIISB, type II toxin-antitoxin system SR-25 PF10500.4 ETO34428.1 - 3.9 6.8 7.4 4.3 6.7 5.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.20 ETO34429.1 - 1.1e-60 205.0 0.0 1.6e-60 204.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO34429.1 - 4.3e-24 84.9 0.0 6.5e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 ETO34429.1 - 4e-19 66.4 8.8 1.3e-06 27.2 0.1 4.8 3 1 1 4 4 4 4 EF hand EF-hand_6 PF13405.1 ETO34429.1 - 2.3e-12 45.6 13.3 0.0032 17.2 0.0 5.5 4 1 1 5 5 5 4 EF-hand domain EF-hand_7 PF13499.1 ETO34429.1 - 3.2e-12 46.3 13.2 4.3e-08 33.1 1.9 4.2 2 1 2 5 5 4 2 EF-hand domain pair EF-hand_8 PF13833.1 ETO34429.1 - 1.7e-09 37.1 5.9 0.0073 15.8 0.1 4.1 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 ETO34429.1 - 2.8e-09 35.8 14.6 0.0015 17.7 0.1 4.6 4 1 1 5 5 5 3 EF hand APH PF01636.18 ETO34429.1 - 3e-05 23.8 0.1 6.3e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 ETO34429.1 - 0.00012 21.4 0.4 0.00029 20.2 0.2 1.6 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.4 ETO34429.1 - 0.0045 16.3 0.0 0.013 14.8 0.0 1.7 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 ETO34429.1 - 0.0059 15.4 0.3 0.0059 15.4 0.2 2.0 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.15 ETO34429.1 - 0.0089 15.6 0.9 0.014 14.9 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.9 ETO34429.1 - 0.044 12.8 0.1 0.086 11.9 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_4 PF12763.2 ETO34429.1 - 0.056 13.1 0.1 0.16 11.7 0.1 1.7 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 ETO34429.1 - 0.096 12.7 3.1 2.4 8.2 2.2 2.9 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region LisH PF08513.6 ETO34429.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 LisH MFMR PF07777.6 ETO34429.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 G-box binding protein MFMR NACHT PF05729.7 ETO34430.1 - 1.4e-07 31.3 0.0 2.1e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 ETO34430.1 - 0.0014 17.5 0.7 0.0039 16.0 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain AAA_19 PF13245.1 ETO34430.1 - 0.0081 15.8 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Part of AAA domain Torsin PF06309.6 ETO34430.1 - 0.01 15.6 0.1 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_16 PF13191.1 ETO34430.1 - 0.012 15.6 0.0 0.027 14.4 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain DAP3 PF10236.4 ETO34430.1 - 0.016 14.1 0.0 0.032 13.1 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 SMC_N PF02463.14 ETO34430.1 - 0.017 14.3 1.7 0.04 13.1 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 ETO34430.1 - 0.023 14.8 0.0 0.09 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain PRK PF00485.13 ETO34430.1 - 0.11 12.0 0.4 10 5.5 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 ETO34430.1 - 0.12 12.7 1.5 0.52 10.6 0.0 2.5 2 1 0 2 2 2 0 AAA domain FRG2 PF15315.1 ETO34430.1 - 0.12 12.3 2.0 0.22 11.4 1.4 1.4 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 DUF87 PF01935.12 ETO34430.1 - 0.87 9.3 0.1 0.87 9.3 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF87 Med2 PF11214.3 ETO34430.1 - 7.9 6.5 13.2 9.3 6.3 6.0 2.4 2 1 0 2 2 2 0 Mediator complex subunit 2 MPC PF03650.8 ETO34431.1 - 0.067 13.1 0.1 3.5 7.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0041) HEAT_EZ PF13513.1 ETO34432.1 - 0.00023 21.5 0.0 0.051 14.0 0.0 3.6 3 1 1 4 4 4 1 HEAT-like repeat CLASP_N PF12348.3 ETO34432.1 - 0.00064 19.1 0.5 0.0049 16.2 0.0 2.4 3 1 0 3 3 3 1 CLASP N terminal HEAT PF02985.17 ETO34432.1 - 0.0013 18.6 0.1 0.07 13.2 0.0 3.5 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.1 ETO34432.1 - 0.0053 17.0 0.0 0.11 12.7 0.0 2.6 1 1 1 2 2 2 1 HEAT repeats Vac14_Fab1_bd PF12755.2 ETO34432.1 - 0.048 14.0 0.9 2.5 8.5 0.0 2.9 2 1 0 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.11 ETO34432.1 - 0.075 13.5 0.0 68 4.3 0.0 3.6 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat DUF3944 PF13099.1 ETO34432.1 - 0.71 9.4 5.2 9.9 5.7 0.4 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3944) zf-RING_2 PF13639.1 ETO34434.1 - 0.0012 18.5 0.9 0.0012 18.5 0.6 2.4 2 0 0 2 2 2 1 Ring finger domain Cse1 PF08506.5 ETO34434.1 - 0.0026 16.3 0.5 0.0045 15.5 0.3 1.4 1 0 0 1 1 1 1 Cse1 zf-C3HC4_2 PF13923.1 ETO34434.1 - 0.012 15.6 0.4 0.012 15.6 0.3 3.2 2 2 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Rifin_STEVOR PF02009.11 ETO34436.1 - 0.00049 19.8 0.2 0.00094 18.9 0.1 1.5 1 0 0 1 1 1 1 Rifin/stevor family Amnionless PF14828.1 ETO34436.1 - 0.0042 15.6 2.3 0.12 10.7 0.0 2.2 2 0 0 2 2 2 1 Amnionless DUF2681 PF10883.3 ETO34436.1 - 0.0091 16.1 0.6 0.031 14.4 0.4 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2681) OSTbeta PF15048.1 ETO34436.1 - 0.0093 16.0 2.7 0.79 9.8 0.2 2.6 2 0 0 2 2 2 1 Organic solute transporter subunit beta protein MFS_1 PF07690.11 ETO34436.1 - 0.01 14.5 0.0 0.03 13.0 0.0 1.6 1 1 0 1 1 1 0 Major Facilitator Superfamily DUF1510 PF07423.6 ETO34436.1 - 0.012 15.0 7.8 0.017 14.4 2.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) SP_C-Propep PF08999.5 ETO34436.1 - 0.015 14.7 0.2 0.048 13.1 0.1 1.8 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide CcmD PF04995.9 ETO34436.1 - 0.034 13.8 4.1 0.08 12.6 2.9 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF4381 PF14316.1 ETO34436.1 - 0.042 13.9 0.1 0.097 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) EphA2_TM PF14575.1 ETO34436.1 - 0.054 13.8 0.1 0.054 13.8 0.0 2.9 3 0 0 3 3 2 0 Ephrin type-A receptor 2 transmembrane domain DUF1469 PF07332.6 ETO34436.1 - 0.15 11.7 0.2 0.15 11.7 0.1 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF1469) Pex24p PF06398.6 ETO34436.1 - 0.18 10.5 5.2 0.22 10.3 0.3 2.1 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin Shisa PF13908.1 ETO34436.1 - 1.9 8.6 6.7 9.3 6.3 4.7 2.1 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator HemY_N PF07219.8 ETO34436.1 - 3.6 7.1 6.3 0.74 9.3 0.3 2.3 2 0 0 2 2 2 0 HemY protein N-terminus Sugar_tr PF00083.19 ETO34437.1 - 1.6e-11 43.5 1.9 1.9e-05 23.4 0.4 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 ETO34437.1 - 4.5e-11 42.0 12.7 5.6e-08 31.8 3.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 ETO34437.1 - 0.00023 20.0 1.9 0.0056 15.4 0.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF791) DUF3357 PF11837.3 ETO34437.1 - 0.0033 17.2 0.0 0.0065 16.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) DUF843 PF05814.6 ETO34437.1 - 0.0077 15.9 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 Baculovirus protein of unknown function (DUF843) DUF2763 PF10961.3 ETO34437.1 - 0.042 14.2 0.1 0.042 14.2 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2763) Pex14_N PF04695.8 ETO34437.1 - 0.051 13.6 0.0 3.6 7.6 0.0 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Oxidored_q3 PF00499.15 ETO34437.1 - 0.24 11.1 7.3 0.059 13.1 1.4 2.3 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF443 PF04276.7 ETO34437.1 - 0.37 10.2 5.9 0.14 11.6 2.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF443) Sigma_reg_N PF13800.1 ETO34437.1 - 2.2 8.3 7.2 0.75 9.8 0.2 2.7 3 0 0 3 3 3 0 Sigma factor regulator N-terminal DUF1738 PF08401.6 ETO34438.1 - 0.0025 17.5 0.5 0.0045 16.7 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1738) DUF4272 PF14094.1 ETO34438.1 - 0.034 13.1 0.4 0.075 12.0 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4272) Myosin_HC-like PF07058.6 ETO34439.1 - 0.0026 16.8 0.0 0.0037 16.4 0.0 1.1 1 0 0 1 1 1 1 Myosin II heavy chain-like An_peroxidase PF03098.10 ETO34440.1 - 2.2e-47 161.6 0.3 7.1e-29 100.5 0.0 3.0 2 1 0 2 2 2 2 Animal haem peroxidase DOMON PF03351.12 ETO34441.1 - 4.1e-15 55.7 0.1 6.8e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 DOMON domain An_peroxidase PF03098.10 ETO34441.1 - 2.1e-10 39.6 0.0 3.2e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase zf-CCHC_3 PF13917.1 ETO34442.1 - 6.3e-09 35.4 7.8 1.5e-08 34.2 5.4 1.7 1 0 0 1 1 1 1 Zinc knuckle MIP-T3 PF10243.4 ETO34442.1 - 0.00011 20.8 24.0 0.00012 20.6 16.6 1.0 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 BUD22 PF09073.5 ETO34442.1 - 0.11 11.4 41.9 0.15 11.1 29.0 1.1 1 0 0 1 1 1 0 BUD22 Macoilin PF09726.4 ETO34442.1 - 1.9 6.6 31.4 2.6 6.2 21.8 1.2 1 0 0 1 1 1 0 Transmembrane protein F-box-like PF12937.2 ETO34444.1 - 0.0051 16.5 0.0 0.0088 15.7 0.0 1.3 1 0 0 1 1 1 1 F-box-like Mito_fiss_reg PF05308.6 ETO34444.1 - 0.047 13.0 0.4 0.047 13.0 0.2 1.8 2 0 0 2 2 2 0 Mitochondrial fission regulator ECH PF00378.15 ETO34445.1 - 1.1e-37 129.5 0.0 1.3e-37 129.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF2320 PF10082.4 ETO34446.1 - 0.035 12.8 10.9 0.04 12.6 7.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2320) RRM_1 PF00076.17 ETO34447.1 - 1.4e-16 59.9 0.0 2.2e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO34447.1 - 3e-09 36.7 0.0 8.7e-09 35.2 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO34447.1 - 1.2e-05 25.0 0.0 2.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CoaE PF01121.15 ETO34448.1 - 6e-26 90.9 0.9 3.8e-25 88.3 0.6 1.9 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 ETO34448.1 - 1.6e-06 28.9 0.4 3.9e-06 27.6 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETO34448.1 - 0.001 19.3 2.7 0.001 19.3 1.9 2.2 1 1 1 2 2 2 1 AAA domain MobB PF03205.9 ETO34448.1 - 0.0016 18.1 1.0 0.0024 17.6 0.2 1.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 ETO34448.1 - 0.0034 17.2 0.1 0.016 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 ETO34448.1 - 0.0086 16.0 0.2 0.014 15.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ETO34448.1 - 0.0097 16.0 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 ETO34448.1 - 0.012 15.8 2.8 0.023 14.9 1.9 1.8 1 1 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 ETO34448.1 - 0.021 13.9 0.3 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin GTP_EFTU PF00009.22 ETO34448.1 - 0.023 14.1 0.3 0.023 14.1 0.2 1.9 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 ETO34448.1 - 0.054 13.0 0.1 0.11 12.0 0.0 1.6 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein Miro PF08477.8 ETO34448.1 - 0.067 13.6 0.2 0.16 12.4 0.1 1.9 1 1 0 1 1 1 0 Miro-like protein tRNA_lig_kinase PF08303.6 ETO34448.1 - 0.11 12.4 6.6 0.15 11.9 0.6 2.7 2 1 0 2 2 2 0 tRNA ligase kinase domain T2SE PF00437.15 ETO34448.1 - 0.25 10.2 2.1 2.8 6.7 0.0 2.7 3 0 0 3 3 3 0 Type II/IV secretion system protein YqfQ PF14181.1 ETO34449.1 - 6.8 6.6 9.3 7 6.6 6.4 1.0 1 0 0 1 1 1 0 YqfQ-like protein Pkinase PF00069.20 ETO34450.1 - 1.2e-32 113.0 0.0 1.4e-32 112.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO34450.1 - 7.5e-05 21.9 0.1 0.00013 21.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase IPK PF03770.11 ETO34450.1 - 0.0079 15.8 1.4 0.012 15.2 1.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase PH PF00169.24 ETO34451.1 - 2e-05 24.7 0.5 2e-05 24.7 0.3 2.5 2 1 0 2 2 2 1 PH domain CobT PF06213.7 ETO34451.1 - 0.00057 19.1 0.2 0.00097 18.3 0.2 1.3 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT FLO_LFY PF01698.11 ETO34451.1 - 0.0029 16.5 0.3 0.0053 15.6 0.2 1.4 1 0 0 1 1 1 1 Floricaula / Leafy protein DUF2457 PF10446.4 ETO34451.1 - 0.023 13.4 5.5 0.042 12.5 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Secretin_N_2 PF07655.8 ETO34451.1 - 1.2 9.5 26.2 5.4 7.4 18.2 2.1 1 0 0 1 1 1 0 Secretin N-terminal domain Pex14_N PF04695.8 ETO34451.1 - 2 8.4 9.8 0.62 10.1 4.5 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Cluap1 PF10234.4 ETO34451.1 - 2 7.5 11.9 1.2 8.3 1.7 2.3 2 0 0 2 2 2 0 Clusterin-associated protein-1 Nop25 PF09805.4 ETO34451.1 - 2.1 8.4 10.3 0.043 13.8 1.7 2.0 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) FAM60A PF15396.1 ETO34451.1 - 3.5 7.3 9.2 4 7.1 2.3 2.2 2 0 0 2 2 2 0 Protein Family FAM60A NOA36 PF06524.7 ETO34451.1 - 9.7 5.3 11.9 16 4.6 8.3 1.3 1 0 0 1 1 1 0 NOA36 protein DUF3507 PF12015.3 ETO34454.1 - 0.14 11.6 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) HEAT_2 PF13646.1 ETO34455.1 - 4.5e-11 42.8 0.6 0.00074 19.7 0.0 5.7 3 2 1 4 4 4 3 HEAT repeats HEAT PF02985.17 ETO34455.1 - 8.1e-09 34.8 0.4 0.22 11.6 0.0 6.8 8 0 0 8 8 8 2 HEAT repeat Cnd1 PF12717.2 ETO34455.1 - 6.9e-05 22.7 21.0 0.0054 16.6 4.2 4.5 2 1 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Ank_2 PF12796.2 ETO34455.1 - 0.00011 22.4 0.2 0.0026 18.0 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO34455.1 - 0.00014 22.0 0.1 0.00052 20.1 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETO34455.1 - 0.00024 21.5 1.4 0.0025 18.2 0.1 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) HEAT_EZ PF13513.1 ETO34455.1 - 0.00055 20.3 0.3 0.86 10.1 0.0 5.2 5 0 0 5 5 5 1 HEAT-like repeat Ank_3 PF13606.1 ETO34455.1 - 0.0012 18.9 0.1 0.027 14.7 0.0 3.3 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.25 ETO34455.1 - 0.0021 17.7 0.0 0.024 14.4 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat PMR5N PF14416.1 ETO34456.1 - 0.024 14.6 0.3 0.072 13.1 0.0 1.9 2 1 0 2 2 2 0 PMR5 N terminal Domain Alg6_Alg8 PF03155.10 ETO34456.1 - 0.093 11.5 0.1 0.11 11.3 0.0 1.0 1 0 0 1 1 1 0 ALG6, ALG8 glycosyltransferase family DUF2408 PF10303.4 ETO34456.1 - 0.2 11.7 0.9 0.26 11.3 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) RAMP PF04901.8 ETO34458.1 - 0.0078 15.9 0.1 0.017 14.9 0.1 1.5 1 0 0 1 1 1 1 Receptor activity modifying family DUF2654 PF10849.3 ETO34458.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2654) EphA2_TM PF14575.1 ETO34459.1 - 0.0061 16.9 1.7 0.085 13.2 0.6 2.6 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain 7tm_1 PF00001.16 ETO34459.1 - 0.0062 15.7 1.2 0.047 12.8 0.8 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) EssA PF10661.4 ETO34459.1 - 0.067 12.8 0.1 0.067 12.8 0.0 2.1 2 1 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA Syndecan PF01034.15 ETO34459.1 - 0.16 11.6 1.8 0.34 10.6 1.2 1.5 1 0 0 1 1 1 0 Syndecan domain PAP2 PF01569.16 ETO34460.1 - 0.00073 19.2 2.5 0.00073 19.2 1.8 2.4 2 1 0 2 2 2 1 PAP2 superfamily Pox_T4_C PF04490.7 ETO34460.1 - 0.002 17.8 0.9 0.002 17.8 0.6 1.7 2 0 0 2 2 2 1 Poxvirus T4 protein, C terminus Transposase_24 PF03004.9 ETO34460.1 - 0.012 15.4 0.5 0.024 14.5 0.3 1.4 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) Methyltransf_28 PF02636.12 ETO34460.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase ABC2_membrane_2 PF12679.2 ETO34460.1 - 0.13 11.0 5.1 0.18 10.6 3.1 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein Plasmodium_Vir PF05795.6 ETO34461.1 - 0.0018 17.5 2.4 0.0021 17.3 1.7 1.1 1 0 0 1 1 1 1 Plasmodium vivax Vir protein VIT1 PF01988.14 ETO34461.1 - 0.036 13.5 0.0 0.048 13.1 0.0 1.1 1 0 0 1 1 1 0 VIT family RRN3 PF05327.6 ETO34461.1 - 0.062 11.4 9.2 0.074 11.1 6.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol3_tau_4 PF12168.3 ETO34461.1 - 0.27 11.6 5.2 0.51 10.7 3.4 1.7 1 1 0 1 1 1 0 DNA polymerase III subunits tau domain IV DnaB-binding CtaG_Cox11 PF04442.9 ETO34461.1 - 0.36 10.6 2.6 0.6 9.8 1.8 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein CtaG/Cox11 DNA_pol_phi PF04931.8 ETO34461.1 - 1.1 6.9 14.1 1.4 6.5 9.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2142 PF09913.4 ETO34461.1 - 3 6.4 9.5 0.26 9.9 2.8 1.8 1 1 2 3 3 3 0 Predicted membrane protein (DUF2142) SGT1 PF07093.6 ETO34461.1 - 8.3 4.6 17.5 9.9 4.4 12.1 1.0 1 0 0 1 1 1 0 SGT1 protein LRR_1 PF00560.28 ETO34462.1 - 3e-07 29.5 17.1 0.3 11.2 0.1 7.8 8 0 0 8 8 8 3 Leucine Rich Repeat LRR_4 PF12799.2 ETO34462.1 - 2e-06 27.2 16.3 0.052 13.1 0.1 4.9 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO34462.1 - 2.4e-05 23.9 1.6 2.4e-05 23.9 1.1 3.3 3 1 0 4 4 4 1 Leucine rich repeat LRR_7 PF13504.1 ETO34462.1 - 0.045 13.9 7.8 25 5.6 0.1 6.6 5 0 0 5 5 5 0 Leucine rich repeat UPF0139 PF03669.8 ETO34462.1 - 0.83 9.2 5.2 3.7 7.1 0.2 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) LRR_6 PF13516.1 ETO34462.1 - 1.6 9.0 15.0 0.73 10.0 0.1 5.1 6 0 0 6 6 6 0 Leucine Rich repeat Solute_trans_a PF03619.11 ETO34464.1 - 0.017 14.4 1.5 0.051 12.8 1.0 1.7 1 1 0 1 1 1 0 Organic solute transporter Ostalpha Dicty_CAR PF05462.6 ETO34467.1 - 2.4e-13 49.6 15.7 1.9e-12 46.7 6.8 2.2 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 ETO34467.1 - 2.9e-11 42.9 17.9 1.8e-09 37.0 6.4 2.5 3 0 0 3 3 3 2 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.16 ETO34467.1 - 0.0023 17.1 13.0 0.094 11.8 5.5 2.3 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) NDUF_B8 PF05821.6 ETO34467.1 - 0.094 12.3 1.2 8.9 5.9 0.1 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) WD40 PF00400.27 ETO34469.1 - 5.1e-54 178.3 21.9 4.9e-12 45.2 0.1 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO34469.1 - 1.5e-12 46.4 2.4 0.0015 16.7 0.1 4.9 2 1 2 4 4 4 4 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO34469.1 - 0.0034 17.2 0.0 3.8 7.5 0.0 3.8 2 1 2 4 4 4 2 Domain of unknown function (DUF3601) MAM PF00629.18 ETO34471.1 - 0.011 15.5 0.7 0.019 14.7 0.4 1.4 1 1 0 1 1 1 0 MAM domain G-alpha PF00503.15 ETO34472.1 - 1.7e-23 82.9 4.5 4.3e-16 58.6 0.5 2.1 2 0 0 2 2 2 2 G-protein alpha subunit Arf PF00025.16 ETO34472.1 - 0.0073 15.5 0.2 0.1 11.8 0.1 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family Virul_fac_BrkB PF03631.10 ETO34472.1 - 0.033 13.5 3.8 0.047 13.0 2.6 1.2 1 0 0 1 1 1 0 Virulence factor BrkB DUF3671 PF12420.3 ETO34472.1 - 0.073 13.0 1.9 0.15 12.0 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function NS3_envE PF02723.9 ETO34472.1 - 3 7.8 18.9 1.6 8.6 1.9 3.2 3 0 0 3 3 3 0 Non-structural protein NS3/Small envelope protein E zf-DHHC PF01529.15 ETO34472.1 - 8.4 5.7 9.7 21 4.4 6.7 1.7 1 0 0 1 1 1 0 DHHC palmitoyltransferase S4 PF01479.20 ETO34473.1 - 0.13 11.6 0.1 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 S4 domain S4 PF01479.20 ETO34474.1 - 1 8.8 3.1 1.2 8.6 0.0 2.7 3 0 0 3 3 3 0 S4 domain WD40 PF00400.27 ETO34475.1 - 8.2e-62 203.0 28.8 5.5e-11 41.9 0.1 7.3 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO34475.1 - 8e-07 27.5 7.9 0.0067 14.6 0.1 4.7 3 2 1 4 4 4 3 Nucleoporin Nup120/160 DUF1030 PF06270.6 ETO34475.1 - 2.6 7.6 5.1 1.3 8.6 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1030) PG_binding_4 PF12229.3 ETO34476.1 - 0.022 14.9 2.2 0.031 14.5 1.5 1.3 1 0 0 1 1 1 0 Putative peptidoglycan binding domain Rab5-bind PF09311.6 ETO34477.1 - 0.0075 16.1 7.3 0.0075 16.1 5.1 2.0 2 1 0 2 2 2 1 Rabaptin-like protein Atg14 PF10186.4 ETO34477.1 - 0.023 13.6 7.5 0.011 14.6 3.1 1.8 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 CCDC155 PF14662.1 ETO34477.1 - 0.025 14.1 8.1 0.067 12.7 0.7 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 DivIVA PF05103.8 ETO34477.1 - 0.055 13.5 0.8 0.055 13.5 0.5 2.6 3 1 1 4 4 4 0 DivIVA protein APG6 PF04111.7 ETO34477.1 - 0.076 12.0 6.0 0.16 11.0 4.1 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 Myosin_tail_1 PF01576.14 ETO34477.1 - 0.096 10.3 6.6 0.13 9.9 4.5 1.2 1 0 0 1 1 1 0 Myosin tail Muted PF14942.1 ETO34477.1 - 0.55 10.0 6.1 6 6.7 1.3 2.7 2 1 1 3 3 3 0 Organelle biogenesis, Muted-like protein Leu_zip PF15294.1 ETO34477.1 - 0.64 9.0 13.3 0.029 13.4 4.9 1.9 3 0 0 3 3 3 0 Leucine zipper CENP-F_leu_zip PF10473.4 ETO34477.1 - 0.69 9.7 11.6 0.075 12.8 4.3 2.1 3 1 0 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.3 ETO34477.1 - 1.5 8.6 13.9 0.048 13.4 3.1 2.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.3 ETO34477.1 - 1.9 8.2 13.7 0.26 11.0 1.3 3.2 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF904 PF06005.7 ETO34477.1 - 3.9 7.8 13.5 2.7 8.3 3.3 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF904) MCC-bdg_PDZ PF10506.4 ETO34477.1 - 4.5 7.1 8.6 0.13 12.1 1.2 2.1 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome SseC PF04888.7 ETO34477.1 - 5 6.3 6.7 3.7 6.8 1.9 2.1 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family DUF4515 PF14988.1 ETO34477.1 - 5.9 6.4 12.3 0.062 12.9 2.7 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4515) ATG16 PF08614.6 ETO34477.1 - 6 6.6 14.8 0.67 9.7 6.7 2.0 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Arf PF00025.16 ETO34478.1 - 7.6e-25 87.1 0.8 7.1e-24 83.9 0.5 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 ETO34478.1 - 2.8e-08 33.3 0.2 3.6e-07 29.7 0.1 2.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 ETO34478.1 - 6.9e-06 26.5 0.7 3.4e-05 24.3 0.5 1.9 1 1 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 ETO34478.1 - 0.00011 22.5 0.0 0.0004 20.6 0.0 1.7 1 1 0 1 1 1 1 ABC transporter SRPRB PF09439.5 ETO34478.1 - 0.00025 20.3 0.9 0.004 16.3 0.6 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 ETO34478.1 - 0.00042 19.8 0.0 0.028 13.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 ETO34478.1 - 0.00064 19.6 0.3 0.0017 18.2 0.2 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 ETO34478.1 - 0.0069 16.5 0.0 0.01 16.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 ETO34478.1 - 0.0079 15.8 2.0 0.083 12.5 1.4 1.9 1 1 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO34478.1 - 0.0095 16.2 0.1 0.015 15.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO34478.1 - 0.011 16.5 0.0 0.023 15.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 ETO34478.1 - 0.015 15.1 0.1 0.02 14.7 0.1 1.3 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 ETO34478.1 - 0.057 12.9 0.2 2.3 7.7 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.1 ETO34478.1 - 0.077 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 ETO34478.1 - 0.14 12.4 3.1 0.76 10.0 2.2 2.0 1 1 0 1 1 1 0 AAA domain DUF3888 PF13027.1 ETO34478.1 - 0.14 12.0 1.0 0.27 11.1 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3888) G-alpha PF00503.15 ETO34478.1 - 0.33 9.6 4.8 2 7.0 0.2 2.5 1 1 2 3 3 3 0 G-protein alpha subunit AAA_5 PF07728.9 ETO34480.1 - 1.9e-13 50.3 0.0 4.9e-13 49.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_6 PF12774.2 ETO34480.1 - 1.4e-12 47.6 0.0 2.3e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_18 PF13238.1 ETO34480.1 - 0.0021 18.3 0.9 0.013 15.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 ETO34480.1 - 0.0074 15.7 0.0 0.021 14.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3987 PF13148.1 ETO34480.1 - 0.014 13.9 0.0 0.025 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_17 PF13207.1 ETO34480.1 - 0.045 14.5 0.0 0.15 12.8 0.0 1.9 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 ETO34480.1 - 0.057 13.7 0.1 0.22 11.7 0.0 1.9 2 1 0 2 2 2 0 ABC transporter Gtr1_RagA PF04670.7 ETO34480.1 - 0.064 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region HMG_box_5 PF14887.1 ETO34480.1 - 0.092 12.5 0.4 0.19 11.5 0.3 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box 5 AAA_33 PF13671.1 ETO34480.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain DNA_pol3_a_NII PF11490.3 ETO34482.1 - 0.28 10.8 6.1 0.074 12.6 1.9 1.7 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II PhzC-PhzF PF02567.11 ETO34484.1 - 1e-18 67.5 0.0 1e-18 67.5 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein CDC45 PF02724.9 ETO34485.1 - 0.42 8.5 3.1 0.71 7.8 2.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 ETO34485.1 - 2.7 7.4 10.0 5 6.6 6.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin Sporozoite_P67 PF05642.6 ETO34485.1 - 8.2 4.1 5.4 11 3.6 3.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen p53-inducible11 PF14936.1 ETO34487.1 - 0.02 14.8 0.5 0.21 11.5 0.4 2.0 1 1 0 1 1 1 0 Tumour protein p53-inducible protein 11 HSP70 PF00012.15 ETO34489.1 - 2.9e-27 94.8 0.0 4.5e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Hsp70 protein SCP2_2 PF13530.1 ETO34489.1 - 0.19 11.1 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Sterol carrier protein domain 2-Hacid_dh_C PF02826.14 ETO34490.1 - 6.5e-50 168.7 0.0 1.2e-49 167.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 ETO34490.1 - 8.3e-26 90.0 0.0 2e-25 88.7 0.0 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 ETO34490.1 - 9.5e-05 22.2 0.1 0.00021 21.1 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 ETO34490.1 - 0.0088 15.8 0.1 0.018 14.8 0.1 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.1 ETO34490.1 - 0.027 14.7 0.0 0.82 9.9 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain ELFV_dehydrog PF00208.16 ETO34490.1 - 0.031 13.8 0.2 0.051 13.1 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase UBA_3 PF09288.5 ETO34490.1 - 0.037 13.6 0.0 0.097 12.2 0.0 1.7 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain UDPG_MGDP_dh_N PF03721.9 ETO34490.1 - 1 8.6 5.2 1 8.6 0.6 2.9 2 1 2 4 4 4 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SPT16 PF08644.6 ETO34491.1 - 0.047 13.5 5.0 0.13 12.1 2.3 2.2 2 1 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) TraC_F_IV PF11130.3 ETO34492.1 - 0.24 10.7 1.6 1.7 8.0 0.6 2.4 2 1 0 2 2 2 0 F pilus assembly Type-IV secretion system for plasmid transfer Ras PF00071.17 ETO34493.1 - 8.4e-14 51.2 3.2 5.3e-05 22.6 0.0 3.9 3 1 0 3 3 3 3 Ras family Miro PF08477.8 ETO34493.1 - 3.7e-09 37.1 0.3 0.035 14.6 0.0 3.6 3 0 0 3 3 3 3 Miro-like protein DUF2981 PF11200.3 ETO34495.1 - 0.1 11.6 14.7 0.13 11.3 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) DUF2718 PF10918.3 ETO34496.1 - 0.49 10.4 3.0 0.53 10.3 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2718) DUF1510 PF07423.6 ETO34496.1 - 1.3 8.3 10.4 1.4 8.2 7.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) ComGG PF14173.1 ETO34497.1 - 0.013 15.6 0.0 0.034 14.3 0.0 1.7 2 0 0 2 2 2 0 ComG operon protein 7 CPT PF07931.7 ETO34497.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.6 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein TPR_11 PF13414.1 ETO34498.1 - 1.2e-18 66.4 6.6 4.9e-14 51.7 0.5 2.4 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 ETO34498.1 - 6.1e-11 41.3 2.5 0.00038 20.1 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO34498.1 - 5.5e-10 38.4 5.9 0.0011 18.4 0.5 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO34498.1 - 1.4e-08 34.2 5.0 0.0054 16.8 0.0 4.1 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO34498.1 - 3.7e-07 30.2 0.2 0.013 16.0 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO34498.1 - 1e-06 29.2 1.9 0.00024 21.6 0.3 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO34498.1 - 0.00016 21.9 1.5 0.03 14.6 0.8 3.0 1 1 1 2 2 2 1 Tetratricopeptide repeat SGT1 PF07093.6 ETO34498.1 - 0.00053 18.5 7.3 0.00095 17.6 5.0 1.4 1 1 0 1 1 1 1 SGT1 protein TPR_7 PF13176.1 ETO34498.1 - 0.0083 15.8 0.1 0.73 9.7 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO34498.1 - 0.033 14.1 5.3 0.056 13.3 1.5 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETO34498.1 - 0.033 13.9 0.1 0.033 13.9 0.1 2.7 4 0 0 4 4 3 0 Tetratricopeptide repeat Dicty_REP PF05086.7 ETO34498.1 - 0.15 9.8 4.8 0.21 9.3 3.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MIT PF04212.13 ETO34498.1 - 0.24 11.2 7.8 3.8 7.4 0.4 3.9 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 ETO34498.1 - 0.42 11.1 3.2 0.95 10.0 0.6 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat XPC-binding PF09280.6 ETO34498.1 - 0.52 9.8 13.2 0.67 9.4 7.8 2.2 2 1 0 2 2 2 0 XPC-binding domain DHHW PF14286.1 ETO34498.1 - 1.4 8.1 13.0 0.26 10.5 5.0 2.2 2 0 0 2 2 2 0 DHHW protein Pex14_N PF04695.8 ETO34498.1 - 2.8 8.0 13.0 0.18 11.8 4.0 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DDHD PF02862.12 ETO34498.1 - 3.3 7.4 8.7 0.55 9.9 3.2 1.7 2 0 0 2 2 2 0 DDHD domain PDZ_2 PF13180.1 ETO34499.1 - 9.2e-06 25.4 0.1 2.1e-05 24.3 0.1 1.7 1 1 0 1 1 1 1 PDZ domain PDZ PF00595.19 ETO34499.1 - 0.0067 16.5 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) CCDC92 PF14916.1 ETO34499.1 - 0.05 13.2 0.0 3 7.4 0.0 2.9 2 0 0 2 2 2 0 Coiled-coil domain of unknown function BCDHK_Adom3 PF10436.4 ETO34500.1 - 2.9e-30 104.9 0.0 3.5e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DUF1644 PF07800.7 ETO34502.1 - 0.0091 15.8 0.4 0.0091 15.8 0.3 2.8 1 1 1 3 3 3 2 Protein of unknown function (DUF1644) DUF2353 PF09789.4 ETO34502.1 - 0.025 13.8 6.8 0.018 14.2 3.4 1.6 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) WD40 PF00400.27 ETO34503.1 - 6.4e-10 38.5 0.1 6.4e-10 38.5 0.1 2.9 3 1 0 3 3 3 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO34503.1 - 0.083 11.0 1.1 0.51 8.4 0.2 2.3 1 1 1 2 2 2 0 Nucleoporin Nup120/160 PAN_3 PF08277.7 ETO34503.1 - 0.083 12.5 0.2 0.083 12.5 0.1 2.0 2 1 1 3 3 3 0 PAN-like domain RabGAP-TBC PF00566.13 ETO34504.1 - 4.4e-17 62.2 2.5 7.4e-17 61.5 0.0 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain PI3_PI4_kinase PF00454.22 ETO34506.1 - 3.1e-08 33.3 0.1 0.0067 15.9 0.0 2.5 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase DUF479 PF04336.7 ETO34506.1 - 0.9 9.6 4.0 0.47 10.5 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF479 RXT2_N PF08595.6 ETO34508.1 - 0.04 13.7 0.8 0.04 13.7 0.6 5.1 2 1 1 3 3 3 0 RXT2-like, N-terminal Hid1 PF12722.2 ETO34508.1 - 0.78 7.3 26.8 1.2 6.6 18.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein HBS1_N PF08938.5 ETO34509.1 - 0.033 14.2 0.2 0.063 13.4 0.2 1.4 1 0 0 1 1 1 0 HBS1 N-terminus Cwf_Cwc_15 PF04889.7 ETO34510.1 - 1.1e-38 133.2 22.7 1.8e-38 132.6 15.7 1.3 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein CENP-T PF15511.1 ETO34510.1 - 0.044 13.0 9.2 0.053 12.7 6.4 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Skp1 PF01466.14 ETO34511.1 - 1.8e-38 130.4 0.7 1.8e-38 130.4 0.5 2.0 3 0 0 3 3 3 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 ETO34511.1 - 2.1e-14 53.3 0.0 4.9e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.26 ETO34511.1 - 2e-06 27.7 0.2 3.4e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain Ribosomal_L6 PF00347.18 ETO34512.1 - 2.8e-05 24.5 0.0 8.5e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L6 WD40 PF00400.27 ETO34513.1 - 1.4e-46 154.7 22.7 2.1e-12 46.3 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO34513.1 - 3e-10 40.1 0.5 0.00065 19.4 0.0 3.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO34513.1 - 5.4e-06 24.8 5.2 0.12 10.4 0.1 3.2 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Resistin PF06954.6 ETO34513.1 - 0.00016 21.8 3.7 1.4 9.2 0.0 3.5 2 1 1 3 3 3 2 Resistin Coatomer_WDAD PF04053.9 ETO34513.1 - 0.00058 18.7 4.1 0.0036 16.1 0.5 2.5 1 1 1 2 2 2 2 Coatomer WD associated region PQQ_2 PF13360.1 ETO34513.1 - 0.00082 18.9 0.1 0.0044 16.5 0.0 2.1 1 1 0 1 1 1 1 PQQ-like domain DUF1652 PF07865.6 ETO34513.1 - 0.0018 17.8 0.2 0.072 12.6 0.0 3.3 2 1 2 4 4 4 1 Protein of unknown function (DUF1652) Cytochrom_D1 PF02239.11 ETO34513.1 - 0.0041 15.4 1.0 0.79 7.9 0.1 2.8 1 1 2 3 3 3 2 Cytochrome D1 heme domain TRA-1_regulated PF02343.11 ETO34513.1 - 0.026 14.0 1.1 0.18 11.2 0.0 2.5 2 1 1 3 3 3 0 TRA-1 regulated protein R03H10.4 DPPIV_N PF00930.16 ETO34513.1 - 0.028 13.0 0.2 9.1 4.7 0.0 3.3 1 1 3 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region SGL PF08450.7 ETO34513.1 - 0.029 13.7 0.1 0.094 12.0 0.0 1.9 1 1 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region F420_ligase PF01996.11 ETO34513.1 - 0.054 12.5 0.1 0.17 10.9 0.0 1.7 1 1 1 2 2 2 0 F420-0:Gamma-glutamyl ligase NHL PF01436.16 ETO34513.1 - 0.069 13.1 4.5 13 5.9 0.0 4.5 6 0 0 6 6 6 0 NHL repeat Maelstrom PF13017.1 ETO34514.1 - 0.097 12.1 0.2 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 piRNA pathway germ-plasm component MiaE PF06175.6 ETO34515.1 - 0.0015 18.0 0.1 0.0017 17.7 0.1 1.2 1 0 0 1 1 1 1 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) DUF445 PF04286.7 ETO34515.1 - 0.042 13.3 2.9 0.061 12.8 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) RRM_6 PF14259.1 ETO34516.1 - 0.0079 16.1 0.0 0.85 9.6 0.0 3.1 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DnaJ PF00226.26 ETO34516.1 - 0.0091 15.7 0.1 0.027 14.2 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Gon7 PF08738.5 ETO34516.1 - 0.044 13.7 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 Gon7 family RRM_1 PF00076.17 ETO34516.1 - 0.049 13.2 0.4 2 8.1 0.0 2.9 2 1 1 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DSPc PF00782.15 ETO34517.1 - 8.7e-08 31.8 1.5 0.00011 21.7 0.1 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Citrate_synt PF00285.16 ETO34518.1 - 0.033 12.9 0.0 0.033 12.9 0.0 1.0 1 0 0 1 1 1 0 Citrate synthase Tweety PF04906.8 ETO34518.1 - 0.062 11.7 0.0 0.073 11.4 0.0 1.0 1 0 0 1 1 1 0 Tweety WD40 PF00400.27 ETO34519.1 - 1.2e-80 262.7 13.5 3.6e-13 48.8 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO34519.1 - 7.6e-12 45.3 0.1 9.3e-06 25.4 0.0 2.9 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 ETO34519.1 - 6.7e-08 32.2 0.1 0.00014 21.4 0.0 3.3 1 1 1 3 3 3 1 PQQ-like domain Nup160 PF11715.3 ETO34519.1 - 7.2e-06 24.4 0.3 0.65 8.0 0.0 4.3 1 1 3 5 5 5 2 Nucleoporin Nup120/160 PD40 PF07676.7 ETO34519.1 - 8.1e-05 22.1 7.8 6 6.6 0.1 5.8 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO34519.1 - 0.00014 20.7 8.3 1.4 7.6 3.1 4.7 1 1 2 3 3 3 1 Nup133 N terminal like Coatomer_WDAD PF04053.9 ETO34519.1 - 0.00022 20.1 0.5 0.041 12.6 0.0 2.8 1 1 1 2 2 2 2 Coatomer WD associated region Cytochrom_D1 PF02239.11 ETO34519.1 - 0.00091 17.6 0.5 0.89 7.7 0.0 3.0 1 1 1 3 3 3 1 Cytochrome D1 heme domain BBS2_Mid PF14783.1 ETO34519.1 - 0.0028 17.4 2.6 0.57 9.9 0.0 4.3 2 2 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region PQQ PF01011.16 ETO34519.1 - 0.0061 16.0 0.0 3.6 7.2 0.0 4.4 6 0 0 6 6 5 1 PQQ enzyme repeat DUF3601 PF12208.3 ETO34519.1 - 0.0072 16.2 0.0 4.2 7.3 0.0 3.5 3 2 1 4 4 3 1 Domain of unknown function (DUF3601) Me-amine-dh_H PF06433.6 ETO34519.1 - 0.014 14.0 0.0 3.4 6.2 0.0 3.1 3 0 0 3 3 3 0 Methylamine dehydrogenase heavy chain (MADH) Resistin PF06954.6 ETO34519.1 - 0.018 15.3 0.1 15 5.9 0.0 3.3 2 2 1 3 3 3 0 Resistin DUF1900 PF08954.6 ETO34519.1 - 0.026 14.0 0.0 0.54 9.7 0.0 3.1 2 1 2 4 4 4 0 Domain of unknown function (DUF1900) TFIIIC_delta PF12657.2 ETO34519.1 - 0.04 13.6 0.3 1.2 8.7 0.0 2.8 2 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term DUF1258 PF06869.7 ETO34519.1 - 0.041 12.9 0.5 8.3 5.4 0.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1258) DUF3732 PF12532.3 ETO34519.1 - 0.074 12.5 0.1 9.8 5.6 0.0 3.3 2 2 2 4 4 4 0 Protein of unknown function (DUF3732) Colicin_Ia PF11504.3 ETO34519.1 - 1 9.3 4.2 1.5e+02 2.3 0.0 4.6 6 0 0 6 6 5 0 Colicin Ia Proteasome_A_N PF10584.4 ETO34519.1 - 2.1 7.7 4.8 4.7 6.6 0.0 3.0 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature DUF3490 PF11995.3 ETO34520.1 - 0.0079 15.7 1.5 0.0093 15.5 0.8 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3490) Pkinase PF00069.20 ETO34522.1 - 2.4e-25 89.1 0.0 2.7e-25 88.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO34522.1 - 1.3e-10 40.7 0.0 1.7e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Fve PF09259.6 ETO34523.1 - 0.096 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Fungal immunomodulatory protein Fve Complex1_LYR PF05347.10 ETO34524.1 - 0.0023 17.7 0.2 0.0041 16.8 0.2 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) EST1_DNA_bind PF10373.4 ETO34524.1 - 0.036 13.2 0.5 0.047 12.8 0.3 1.2 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain DUF810 PF05664.6 ETO34524.1 - 0.039 12.2 0.4 0.12 10.5 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF810) Complex1_LYR_1 PF13232.1 ETO34524.1 - 0.044 13.9 0.1 0.077 13.2 0.1 1.4 1 0 0 1 1 1 0 Complex1_LYR-like S_tail_recep_bd PF14928.1 ETO34524.1 - 0.057 13.6 0.1 0.075 13.2 0.1 1.1 1 0 0 1 1 1 0 Short tail fibre protein receptor-binding domain FHA PF00498.21 ETO34525.1 - 1.1e-14 54.3 1.0 2.3e-14 53.2 0.1 2.0 2 0 0 2 2 2 1 FHA domain RGS PF00615.14 ETO34525.1 - 5.4e-09 36.1 8.5 1.8e-08 34.5 5.9 1.9 1 1 0 1 1 1 1 Regulator of G protein signaling domain T4SS PF07996.6 ETO34525.1 - 0.041 13.7 0.5 0.041 13.7 0.4 2.3 1 1 1 2 2 2 0 Type IV secretion system proteins Trp_repressor PF01371.14 ETO34525.1 - 0.045 13.6 0.5 3.4 7.6 0.0 3.0 3 0 0 3 3 3 0 Trp repressor protein CARD PF00619.16 ETO34525.1 - 0.35 10.7 5.1 3.7 7.4 0.1 3.3 2 1 1 3 3 3 0 Caspase recruitment domain WD40 PF00400.27 ETO34526.1 - 1.8e-76 249.4 12.7 6.2e-10 38.5 0.1 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 ETO34526.1 - 1.7e-07 29.8 8.7 0.39 8.8 0.0 6.5 1 1 6 7 7 7 5 Nucleoporin Nup120/160 Pentapeptide PF00805.17 ETO34526.1 - 3.9e-07 29.1 1.0 8.9e-07 28.0 0.7 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO34526.1 - 1.1e-05 25.1 0.1 3.7e-05 23.4 0.1 1.9 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 ETO34526.1 - 4e-05 23.4 0.2 0.00015 21.5 0.1 2.1 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) DUF1258 PF06869.7 ETO34526.1 - 0.00037 19.6 1.0 0.052 12.6 0.1 3.2 1 1 3 4 4 4 2 Protein of unknown function (DUF1258) Cytochrom_D1 PF02239.11 ETO34526.1 - 0.00063 18.1 1.7 0.049 11.9 0.2 2.8 2 1 1 3 3 3 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO34526.1 - 0.081 12.3 0.1 2.7 7.3 0.0 2.5 1 1 1 2 2 2 0 PQQ-like domain WD40 PF00400.27 ETO34527.1 - 1.2e-11 44.0 3.9 2.5e-06 27.1 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat Nbas_N PF15492.1 ETO34527.1 - 0.00052 19.2 0.1 0.45 9.5 0.0 2.2 2 0 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 ETO34527.1 - 0.0021 17.5 0.1 0.49 9.8 0.0 2.1 1 1 1 2 2 2 2 PQQ-like domain DPPIV_N PF00930.16 ETO34527.1 - 0.0029 16.2 0.1 0.0095 14.5 0.0 1.8 1 1 1 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region BetaGal_dom2 PF10435.4 ETO34527.1 - 0.0085 15.4 0.1 0.55 9.5 0.0 2.1 1 1 1 2 2 2 2 Beta-galactosidase, domain 2 PD40 PF07676.7 ETO34527.1 - 0.031 13.9 2.9 6.7 6.4 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF2256 PF10013.4 ETO34528.1 - 0.65 9.7 3.9 0.61 9.8 0.6 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) DAG_kinase_N PF14513.1 ETO34529.1 - 0.13 12.4 0.4 11 6.1 0.0 2.2 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus zf-C2H2 PF00096.21 ETO34531.1 - 0.44 10.9 3.6 2.4 8.6 1.0 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type WD40 PF00400.27 ETO34532.1 - 0.0081 16.0 5.6 0.12 12.2 0.1 3.1 2 1 1 3 3 3 1 WD domain, G-beta repeat VGCC_alpha2 PF08473.6 ETO34532.1 - 0.068 12.9 0.4 0.1 12.3 0.3 1.3 1 0 0 1 1 1 0 Neuronal voltage-dependent calcium channel alpha 2acd DUF3430 PF11912.3 ETO34532.1 - 0.26 11.0 5.4 0.38 10.5 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3430) AP-5_subunit_s1 PF15001.1 ETO34532.1 - 0.33 10.8 5.2 0.46 10.3 3.6 1.3 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 RNA_pol_Rpb1_5 PF04998.12 ETO34532.1 - 0.66 9.1 4.1 0.84 8.8 2.8 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 SMN PF06003.7 ETO34532.1 - 1.3 8.0 5.6 1.6 7.7 3.8 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Merozoite_SPAM PF07133.6 ETO34532.1 - 8.4 6.2 17.5 11 5.8 11.7 1.5 1 1 1 2 2 2 0 Merozoite surface protein (SPAM) Cir_N PF10197.4 ETO34532.1 - 8.5 6.4 12.7 0.39 10.7 2.5 2.3 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR WD40 PF00400.27 ETO34533.1 - 1.7e-55 182.9 22.4 2.7e-11 42.8 0.2 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO34533.1 - 8e-09 34.1 2.9 0.013 13.7 0.0 4.8 1 1 3 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO34533.1 - 0.00082 18.2 6.6 1.5 7.4 0.2 4.4 1 1 1 3 3 3 2 Nup133 N terminal like U-box PF04564.10 ETO34534.1 - 9.3e-11 41.5 0.7 4.2e-10 39.4 0.0 2.6 2 1 0 2 2 2 1 U-box domain GLTSCR1 PF15249.1 ETO34534.1 - 0.25 11.4 3.7 0.51 10.4 1.3 2.5 1 1 2 3 3 3 0 Glioma tumor suppressor candidate region DUF843 PF05814.6 ETO34534.1 - 1.9 8.3 7.7 0.14 11.9 1.3 2.1 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) Pkinase PF00069.20 ETO34536.1 - 7e-21 74.5 0.0 8.2e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO34536.1 - 1.8e-07 30.5 0.0 1.9e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Borrelia_P83 PF05262.6 ETO34536.1 - 0.13 10.5 0.0 0.16 10.2 0.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein zf-C3HC4_3 PF13920.1 ETO34538.1 - 0.0024 17.5 8.0 0.0024 17.5 5.5 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Tudor-knot PF11717.3 ETO34538.1 - 0.015 14.9 0.9 0.043 13.5 0.7 1.8 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain GTP_EFTU_D3 PF03143.12 ETO34539.1 - 1e-09 38.4 0.1 2.4e-09 37.2 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 ETO34539.1 - 7.8e-07 29.1 0.2 1.3e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU PF00009.22 ETO34539.1 - 0.00085 18.7 0.0 0.00094 18.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Myosin_TH1 PF06017.8 ETO34540.1 - 8.2e-18 64.4 6.3 1.1e-17 64.0 4.4 1.1 1 0 0 1 1 1 1 Myosin tail hSac2 PF12456.3 ETO34540.1 - 0.025 13.9 0.1 0.053 12.8 0.1 1.7 1 0 0 1 1 1 0 Inositol phosphatase RabGAP-TBC PF00566.13 ETO34542.1 - 7e-32 110.6 17.2 4.3e-20 72.1 1.4 3.6 3 1 0 3 3 3 2 Rab-GTPase-TBC domain Pkinase PF00069.20 ETO34543.1 - 2.3e-28 99.0 0.1 1e-27 96.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO34543.1 - 2.8e-11 43.0 0.0 1.2e-10 40.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO34543.1 - 8.1e-05 21.7 0.0 0.00018 20.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 ETO34543.1 - 0.00037 19.8 0.3 0.0007 19.0 0.0 1.5 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 ETO34543.1 - 0.00041 19.4 0.0 0.00068 18.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO34543.1 - 0.0039 16.9 0.0 0.0094 15.7 0.0 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF3179 PF11376.3 ETO34543.1 - 0.045 12.9 0.0 1.6 7.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3179) CUE PF02845.11 ETO34544.1 - 0.11 12.0 0.1 0.31 10.5 0.0 1.8 1 0 0 1 1 1 0 CUE domain HAUS6_N PF14661.1 ETO34544.1 - 8.5 5.6 21.1 0.53 9.6 5.4 2.6 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 6 N-terminus WD40 PF00400.27 ETO34546.1 - 9.7e-13 47.4 4.9 5.1e-09 35.6 0.2 3.1 3 1 0 3 3 3 2 WD domain, G-beta repeat ICMT PF04140.9 ETO34546.1 - 0.0037 17.4 0.4 0.0067 16.6 0.3 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 ETO34546.1 - 0.078 13.0 0.1 1.4 9.0 0.0 2.2 1 1 1 2 2 2 0 Phospholipid methyltransferase ESAG1 PF03238.8 ETO34547.1 - 0.01 15.1 0.1 0.017 14.4 0.0 1.4 1 0 0 1 1 1 0 ESAG protein PcfK PF14058.1 ETO34547.1 - 4.1 7.5 12.2 7.7 6.6 1.1 2.2 2 0 0 2 2 2 0 PcfK-like protein zf-C4H2 PF10146.4 ETO34547.1 - 4.7 7.1 14.1 6.6 6.6 9.7 1.3 1 1 0 1 1 1 0 Zinc finger-containing protein IncA PF04156.9 ETO34548.1 - 0.0093 15.5 5.1 0.0093 15.5 3.5 1.8 2 0 0 2 2 2 1 IncA protein 14-3-3 PF00244.15 ETO34549.1 - 6.1e-36 123.6 8.4 9.4e-36 123.0 5.8 1.3 1 0 0 1 1 1 1 14-3-3 protein TLP-20 PF06088.6 ETO34549.1 - 0.02 14.5 0.3 0.037 13.7 0.2 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Drc1-Sld2 PF11719.3 ETO34549.1 - 0.059 12.4 8.3 0.1 11.6 5.8 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein Nucleoplasmin PF03066.10 ETO34549.1 - 4.8 6.6 12.2 8.7 5.8 8.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin ETRAMP PF09716.5 ETO34550.1 - 0.071 13.0 1.3 0.094 12.6 0.9 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) G-patch_2 PF12656.2 ETO34552.1 - 0.00012 21.8 0.1 0.00041 20.1 0.3 1.6 2 0 0 2 2 2 1 DExH-box splicing factor binding site DUF912 PF06024.7 ETO34552.1 - 0.28 11.2 2.3 0.36 10.9 1.6 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3300 PF11737.3 ETO34552.1 - 1.1 8.5 3.9 1.4 8.1 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3300) Secretin_N_2 PF07655.8 ETO34552.1 - 4.3 7.7 10.8 6.8 7.1 7.5 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain SSP160 PF06933.6 ETO34558.1 - 0.89 7.4 14.1 1.2 6.9 9.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 dDENN PF03455.14 ETO34559.1 - 6e-10 39.0 3.7 1e-09 38.2 2.6 1.3 1 0 0 1 1 1 1 dDENN domain Cation_ATPase_C PF00689.16 ETO34560.1 - 6.7e-42 143.0 8.8 6.7e-42 143.0 6.1 1.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 ETO34560.1 - 2.9e-06 27.8 0.0 4e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 ETO34560.1 - 0.0048 16.5 0.6 0.007 15.9 0.4 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF417 PF04224.7 ETO34560.1 - 0.01 15.2 0.9 0.016 14.5 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF417 WD40 PF00400.27 ETO34561.1 - 5.1e-62 203.7 22.9 3.4e-11 42.5 0.3 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO34561.1 - 1.7e-10 39.7 9.8 0.004 15.3 0.2 5.5 2 2 4 6 6 6 5 Nucleoporin Nup120/160 AAA PF00004.24 ETO34562.1 - 2e-21 76.5 0.2 3.3e-21 75.8 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 ETO34562.1 - 2e-07 30.7 0.0 5.8e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 ETO34562.1 - 0.089 12.9 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF4200 PF13863.1 ETO34564.1 - 0.046 13.6 14.5 0.053 13.4 10.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) AAA_assoc_C PF09821.4 ETO34564.1 - 0.065 13.5 3.9 0.067 13.4 1.8 1.6 1 1 1 2 2 2 0 C-terminal AAA-associated domain POC1 PF10450.4 ETO34564.1 - 0.18 10.5 2.1 0.18 10.5 1.5 1.1 1 0 0 1 1 1 0 POC1 chaperone RepB-RCR_reg PF10723.4 ETO34564.1 - 0.46 10.2 7.7 0.093 12.4 2.0 1.9 1 1 1 2 2 2 0 Replication regulatory protein RepB Baculo_LEF-2 PF03041.9 ETO34564.1 - 0.99 9.0 7.4 1.1 8.9 5.1 1.1 1 0 0 1 1 1 0 lef-2 Dynamin_N PF00350.18 ETO34564.1 - 1.2 8.9 6.0 1.3 8.7 4.1 1.1 1 0 0 1 1 1 0 Dynamin family Mem_trans PF03547.13 ETO34564.1 - 2.5 6.3 5.5 2.7 6.1 3.8 1.0 1 0 0 1 1 1 0 Membrane transport protein DUF2207 PF09972.4 ETO34564.1 - 7.9 4.9 9.8 8.9 4.7 6.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3893 PF13032.1 ETO34565.1 - 0.12 12.4 0.2 0.12 12.4 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3893) DUF1473 PF07341.6 ETO34566.1 - 0.1 12.1 8.0 0.063 12.8 2.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1473) B5 PF03484.10 ETO34566.1 - 0.37 10.6 1.9 2.9 7.8 0.1 2.7 2 1 1 3 3 3 0 tRNA synthetase B5 domain DUF3977 PF13122.1 ETO34566.1 - 0.38 10.6 5.5 0.19 11.5 1.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3977) DUF3440 PF11922.3 ETO34566.1 - 0.48 9.9 4.8 0.7 9.4 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) ANTH PF07651.11 ETO34567.1 - 0.0016 17.2 1.0 0.0017 17.1 0.7 1.0 1 0 0 1 1 1 1 ANTH domain ICE2 PF08426.5 ETO34567.1 - 0.0085 14.7 0.1 0.0095 14.5 0.1 1.1 1 0 0 1 1 1 1 ICE2 DUF3357 PF11837.3 ETO34567.1 - 0.0093 15.8 0.2 0.014 15.2 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3357) OATP PF03137.15 ETO34567.1 - 0.012 13.6 0.1 0.014 13.5 0.1 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Eapp_C PF10238.4 ETO34567.1 - 0.013 15.3 6.2 0.016 15.1 4.3 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein Ctr PF04145.10 ETO34567.1 - 0.017 15.1 0.1 0.019 15.0 0.0 1.1 1 0 0 1 1 1 0 Ctr copper transporter family DUF1183 PF06682.7 ETO34567.1 - 0.02 14.5 0.3 0.021 14.4 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) OSTbeta PF15048.1 ETO34567.1 - 0.039 14.0 2.4 0.049 13.7 1.6 1.1 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Tmem26 PF09772.4 ETO34567.1 - 0.074 12.2 0.1 0.089 11.9 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 26 TMEM51 PF15345.1 ETO34567.1 - 0.082 12.5 0.0 0.087 12.5 0.0 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 Mem_trans PF03547.13 ETO34567.1 - 0.088 11.0 0.1 0.092 11.0 0.1 1.0 1 0 0 1 1 1 0 Membrane transport protein Folate_carrier PF01770.13 ETO34567.1 - 0.096 11.1 0.5 0.099 11.1 0.3 1.0 1 0 0 1 1 1 0 Reduced folate carrier EphA2_TM PF14575.1 ETO34567.1 - 0.11 12.9 0.1 0.18 12.2 0.1 1.4 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2615 PF11027.3 ETO34567.1 - 0.23 11.4 4.0 0.55 10.1 2.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2615) Secretin_N_2 PF07655.8 ETO34567.1 - 0.4 11.0 15.4 0.57 10.6 10.7 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain Ion_trans PF00520.26 ETO34567.1 - 1.1 8.4 7.9 1.7 7.8 5.4 1.4 1 1 0 1 1 1 0 Ion transport protein YMF19 PF02326.10 ETO34567.1 - 2.2 8.8 5.7 3.1 8.4 3.8 1.4 1 1 0 1 1 1 0 Plant ATP synthase F0 Peptidase_U32 PF01136.14 ETO34568.1 - 0.062 12.2 0.0 0.09 11.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family U32 DUF2971 PF11185.3 ETO34568.1 - 0.37 11.5 6.1 0.15 12.8 0.4 3.0 2 2 0 2 2 2 0 Protein of unknown function (DUF2971) EcoR124_C PF12008.3 ETO34569.1 - 1e-58 198.6 19.7 1e-58 198.6 13.6 3.3 3 0 0 3 3 3 1 Type I restriction and modification enzyme - subunit R C terminal HSDR_N PF04313.9 ETO34569.1 - 5.1e-43 147.0 11.2 5.1e-43 147.0 7.7 2.7 2 0 0 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) ResIII PF04851.10 ETO34569.1 - 4.7e-19 68.9 1.5 4.7e-19 68.9 1.1 4.1 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 ETO34569.1 - 4.3e-09 36.0 0.1 3.3e-08 33.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase N6_Mtase PF02384.11 ETO34570.1 - 6.7e-91 304.6 3.9 4.9e-46 157.2 0.0 2.6 2 1 1 3 3 3 2 N-6 DNA Methylase Virulence_RhuM PF13310.1 ETO34570.1 - 2.3e-90 302.1 15.0 1.7e-89 299.2 10.4 2.1 1 1 0 1 1 1 1 Virulence protein RhuM family Methylase_S PF01420.14 ETO34570.1 - 8.7e-23 81.1 1.1 8.7e-23 81.1 0.7 2.6 2 1 0 2 2 2 1 Type I restriction modification DNA specificity domain Methyltransf_26 PF13659.1 ETO34570.1 - 7.2e-06 26.0 0.0 2.3e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO34570.1 - 0.0024 17.4 0.1 0.017 14.7 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 ETO34570.1 - 0.036 13.6 1.1 0.22 11.0 0.0 2.7 3 1 0 3 3 3 0 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.2 ETO34570.1 - 0.075 13.6 0.1 0.81 10.2 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain DUF848 PF05852.6 ETO34570.1 - 0.84 9.4 6.8 4.5 7.1 1.2 2.8 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF4238 PF14022.1 ETO34571.1 - 1.2e-07 31.3 15.2 2.2e-07 30.4 10.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4238) GABP-alpha PF11620.3 ETO34571.1 - 0.25 11.3 2.3 6.5 6.8 0.2 2.3 2 0 0 2 2 2 0 GA-binding protein alpha chain FtsJ PF01728.14 ETO34572.1 - 3.3e-55 186.8 0.0 4.1e-55 186.5 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 ETO34572.1 - 9.8e-05 21.9 0.6 0.0084 15.7 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 ETO34572.1 - 0.00018 21.2 0.0 0.00024 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NSP13 PF06460.7 ETO34572.1 - 0.00019 20.4 0.0 0.00026 19.9 0.0 1.2 1 0 0 1 1 1 1 Coronavirus NSP13 Cas_Csy4 PF09618.5 ETO34575.1 - 2.5e-37 128.4 0.3 3.6e-37 127.9 0.2 1.3 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Csy4) DEAD PF00270.24 ETO34577.1 - 1.7e-11 43.8 0.1 3.6e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 ETO34577.1 - 2.2e-10 40.6 0.3 2.2e-10 40.6 0.2 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit BLYB PF05289.6 ETO34577.1 - 3.6e-05 23.5 2.5 0.018 14.8 0.0 3.5 3 0 0 3 3 3 2 Borrelia hemolysin accessory protein SNF2_N PF00176.18 ETO34577.1 - 0.002 17.0 0.0 0.002 17.0 0.0 2.3 3 0 0 3 3 3 1 SNF2 family N-terminal domain AAA_22 PF13401.1 ETO34577.1 - 0.0051 16.9 0.1 0.2 11.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain PhoH PF02562.11 ETO34577.1 - 0.011 15.0 0.1 0.04 13.1 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_16 PF13191.1 ETO34577.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Tmemb_9 PF05434.6 ETO34578.1 - 0.0013 18.5 0.9 0.0019 17.9 0.3 1.4 1 1 1 2 2 2 1 TMEM9 Zip PF02535.17 ETO34578.1 - 0.02 13.8 0.0 0.024 13.6 0.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter OATP PF03137.15 ETO34578.1 - 0.069 11.2 1.0 0.077 11.0 0.7 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Menin PF05053.8 ETO34578.1 - 0.24 9.5 6.6 0.27 9.3 4.6 1.1 1 0 0 1 1 1 0 Menin RP-C_C PF11800.3 ETO34578.1 - 0.48 10.0 6.6 0.75 9.4 4.5 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region COPI_assoc PF08507.5 ETO34578.1 - 1.4 8.6 3.6 7.6 6.2 2.5 1.9 1 1 0 1 1 1 0 COPI associated protein SR-25 PF10500.4 ETO34578.1 - 2.5 7.5 12.5 3.3 7.1 8.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Mem_trans PF03547.13 ETO34578.1 - 9.7 4.3 9.1 12 4.0 6.3 1.3 1 1 0 1 1 1 0 Membrane transport protein DUF600 PF04634.7 ETO34579.1 - 0.022 14.7 1.5 0.027 14.4 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF600 DUF867 PF05908.6 ETO34579.1 - 0.074 12.1 0.1 0.079 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF867) Kelch_1 PF01344.20 ETO34580.1 - 6.7e-06 25.5 4.5 0.0014 18.1 0.7 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 ETO34580.1 - 0.00012 21.9 6.1 0.045 13.7 0.9 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO34580.1 - 0.00023 20.7 5.5 0.49 10.2 0.6 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO34580.1 - 0.0005 20.1 4.0 2.2 8.5 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO34580.1 - 0.059 13.1 3.1 0.16 11.7 0.3 3.0 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO34580.1 - 0.14 12.4 0.4 0.88 9.8 0.2 2.5 2 0 0 2 2 2 0 Galactose oxidase, central domain SPRY PF00622.23 ETO34581.1 - 0.00044 20.3 0.0 0.00074 19.5 0.0 1.4 1 0 0 1 1 1 1 SPRY domain YPEB PF14620.1 ETO34581.1 - 0.0043 16.1 0.1 0.006 15.6 0.1 1.3 1 0 0 1 1 1 1 YpeB sporulation WD40 PF00400.27 ETO34582.1 - 3e-11 42.7 0.8 1e-07 31.5 0.0 3.4 4 0 0 4 4 4 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO34582.1 - 0.032 13.0 0.2 0.049 12.3 0.2 1.4 1 0 0 1 1 1 0 Nup133 N terminal like D123 PF07065.9 ETO34583.1 - 3.8e-11 42.6 11.7 1.5e-08 34.0 0.0 3.4 1 1 2 3 3 3 3 D123 GLYCAM-1 PF05242.6 ETO34583.1 - 0.091 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) TIP49 PF06068.8 ETO34584.1 - 1.7e-35 122.5 0.9 2.2e-35 122.1 0.7 1.1 1 0 0 1 1 1 1 TIP49 C-terminus DUF4410 PF14366.1 ETO34585.1 - 0.12 12.0 10.0 0.73 9.5 1.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4410) Nucleoside_tran PF01733.13 ETO34585.1 - 2.8 6.9 5.8 2.5 7.1 0.2 2.2 2 0 0 2 2 2 0 Nucleoside transporter Draxin PF15550.1 ETO34585.1 - 3.6 7.1 12.4 0.083 12.5 3.9 1.7 2 0 0 2 2 2 0 Draxin Ndc1_Nup PF09531.5 ETO34585.1 - 5.7 5.2 8.7 9.9 4.4 3.1 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Pkinase PF00069.20 ETO34586.1 - 4.2e-32 111.3 0.0 6.7e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO34586.1 - 4.2e-23 81.7 0.0 4.2e-19 68.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 ETO34586.1 - 0.042 12.9 0.1 0.17 10.9 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO34586.1 - 0.11 12.2 0.0 0.29 10.8 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ax_dynein_light PF10211.4 ETO34587.1 - 2.3 8.0 10.7 3.4 7.4 7.4 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain Kelch_3 PF13415.1 ETO34588.1 - 2.8e-06 27.3 0.2 0.00031 20.7 0.0 3.5 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO34588.1 - 9.4e-06 25.3 4.0 0.0017 18.1 0.0 3.8 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO34588.1 - 0.00076 19.5 7.6 0.019 15.1 0.0 4.3 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO34588.1 - 0.02 14.3 7.6 0.028 13.9 0.1 3.7 4 0 0 4 4 4 0 Kelch motif PUB PF09409.5 ETO34589.1 - 0.012 15.3 0.5 0.012 15.3 0.3 2.6 2 0 0 2 2 2 0 PUB domain WD40 PF00400.27 ETO34591.1 - 1.7e-59 195.6 30.9 5.5e-11 41.9 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO34591.1 - 1.8e-07 29.7 9.7 0.028 12.5 0.0 5.1 1 1 3 5 5 5 4 Nucleoporin Nup120/160 Marek_SORF3 PF07153.6 ETO34591.1 - 0.01 14.5 0.6 0.89 8.1 0.0 3.0 2 1 1 3 3 3 0 Marek's disease-like virus SORF3 protein NACHT PF05729.7 ETO34593.1 - 3.5e-09 36.5 0.0 8.7e-09 35.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO34593.1 - 9.6e-06 25.9 0.1 9.6e-06 25.9 0.1 4.1 4 1 1 5 5 5 1 AAA domain AAA_22 PF13401.1 ETO34593.1 - 0.00024 21.2 0.2 0.00024 21.2 0.1 2.7 3 1 0 3 3 3 1 AAA domain AAA_17 PF13207.1 ETO34593.1 - 0.00073 20.3 2.5 0.0019 19.0 0.0 3.0 3 0 0 3 3 3 1 AAA domain UPF0079 PF02367.12 ETO34593.1 - 0.0008 19.0 0.0 0.0028 17.2 0.0 1.9 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 ETO34593.1 - 0.0016 18.6 0.3 0.018 15.2 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATP_bind_2 PF03668.10 ETO34593.1 - 0.005 15.9 0.0 2.8 6.9 0.0 2.7 2 0 0 2 2 2 2 P-loop ATPase protein family AAA_33 PF13671.1 ETO34593.1 - 0.025 14.4 0.0 0.072 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETO34593.1 - 0.07 13.1 0.9 0.64 9.9 0.0 2.6 2 1 1 3 3 3 0 AAA ATPase domain Zn-ribbon_8 PF09723.5 ETO34593.1 - 0.091 12.7 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 Zinc ribbon domain ATP-synt_ab_N PF02874.18 ETO34594.1 - 3.1e-05 24.1 0.0 4.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain A2L_zn_ribbon PF08792.5 ETO34595.1 - 0.022 14.2 1.4 0.077 12.4 0.2 2.4 3 0 0 3 3 3 0 A2L zinc ribbon domain WD40 PF00400.27 ETO34597.1 - 4.2e-73 238.8 11.6 8.7e-13 47.6 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO34597.1 - 7.5e-12 45.3 0.1 3.1e-05 23.7 0.0 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO34597.1 - 9.1e-08 30.6 3.9 3.1e-05 22.3 0.3 3.7 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 ETO34597.1 - 5.4e-07 28.7 0.2 1.7e-05 23.8 0.1 2.5 1 1 1 2 2 2 1 Coatomer WD associated region Nucleoporin_N PF08801.6 ETO34597.1 - 1e-06 27.7 4.3 0.15 10.7 0.0 4.8 1 1 3 4 4 4 2 Nup133 N terminal like PQQ_2 PF13360.1 ETO34597.1 - 1.1e-06 28.2 0.4 8.2e-06 25.4 0.2 2.2 1 1 0 1 1 1 1 PQQ-like domain PD40 PF07676.7 ETO34597.1 - 1.6e-06 27.6 5.3 0.074 12.7 0.0 6.0 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 ETO34597.1 - 4.7e-05 22.6 1.1 4.3 6.3 0.0 4.1 1 1 3 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 ETO34597.1 - 0.0024 16.2 0.3 2.7 6.1 0.0 2.8 1 1 2 4 4 4 3 Cytochrome D1 heme domain Resistin PF06954.6 ETO34597.1 - 0.012 15.8 2.3 15 5.9 0.0 4.4 2 2 4 6 6 6 0 Resistin DUF1258 PF06869.7 ETO34597.1 - 0.015 14.4 0.7 2.5 7.0 0.0 3.2 2 2 2 4 4 4 0 Protein of unknown function (DUF1258) Hira PF07569.6 ETO34597.1 - 0.039 13.1 1.1 28 3.8 0.0 3.8 2 1 3 5 5 5 0 TUP1-like enhancer of split DUF2415 PF10313.4 ETO34597.1 - 0.067 12.8 0.1 2.7 7.7 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) Proteasome_A_N PF10584.4 ETO34597.1 - 0.18 11.1 4.4 4.2 6.7 0.0 4.1 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature IPK PF03770.11 ETO34599.1 - 0.067 12.8 1.2 0.08 12.5 0.9 1.2 1 0 0 1 1 1 0 Inositol polyphosphate kinase eIF3_p135 PF12807.2 ETO34599.1 - 0.33 10.8 2.9 0.67 9.8 2.0 1.6 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 DUF3899 PF13038.1 ETO34599.1 - 0.52 10.5 4.8 1.9 8.7 0.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3899) Med9 PF07544.8 ETO34600.1 - 1.1 9.0 16.3 0.66 9.7 0.4 4.5 3 2 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 FtsL PF04999.8 ETO34601.1 - 0.029 14.0 3.1 0.58 9.9 1.4 2.2 2 0 0 2 2 2 0 Cell division protein FtsL HALZ PF02183.13 ETO34601.1 - 0.058 13.1 3.4 0.086 12.5 1.7 1.9 1 1 0 1 1 1 0 Homeobox associated leucine zipper DUF972 PF06156.8 ETO34601.1 - 1.4 9.2 9.8 2.7 8.3 5.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) CDC48_N PF02359.13 ETO34604.1 - 0.15 12.0 1.0 0.63 10.0 0.1 2.4 4 0 0 4 4 4 0 Cell division protein 48 (CDC48), N-terminal domain DUF2847 PF11009.3 ETO34605.1 - 0.08 12.5 3.7 0.1 12.1 0.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF2847) RRM_1 PF00076.17 ETO34606.1 - 1.5e-32 111.0 0.1 1.7e-16 59.5 0.0 4.2 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO34606.1 - 7.8e-22 77.0 0.0 4e-09 36.3 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO34606.1 - 4.8e-20 71.1 0.6 4.9e-06 26.2 0.0 4.0 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PIG-F PF06699.6 ETO34607.1 - 1.1e-14 54.8 2.8 1.3e-14 54.6 1.9 1.0 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Mem_trans PF03547.13 ETO34607.1 - 0.064 11.5 1.3 0.075 11.3 0.9 1.5 1 1 0 1 1 1 0 Membrane transport protein DUF2273 PF10031.4 ETO34607.1 - 0.37 10.4 4.2 0.27 10.8 0.2 2.4 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) Ion_trans_N PF08412.5 ETO34607.1 - 0.91 8.8 3.1 0.45 9.8 0.4 1.7 2 0 0 2 2 2 0 Ion transport protein N-terminal Dicty_REP PF05086.7 ETO34608.1 - 0.2 9.3 3.7 0.22 9.2 2.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RhoGEF PF00621.15 ETO34609.1 - 7.2e-23 81.3 3.2 8.1e-23 81.2 2.2 1.0 1 0 0 1 1 1 1 RhoGEF domain DUF2947 PF11163.3 ETO34609.1 - 0.0027 17.2 0.3 0.0034 16.9 0.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2947) Rabaptin PF03528.10 ETO34609.1 - 0.079 12.8 1.4 0.11 12.4 0.9 1.2 1 0 0 1 1 1 0 Rabaptin zf-C4H2 PF10146.4 ETO34609.1 - 0.16 11.9 1.3 0.3 11.0 0.9 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein UBA PF00627.26 ETO34611.1 - 9.5e-05 22.1 0.0 0.00023 20.9 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain SR-25 PF10500.4 ETO34611.1 - 1.2 8.5 18.4 2.1 7.7 12.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Vfa1 PF08432.5 ETO34611.1 - 1.8 8.5 17.1 3.1 7.7 11.9 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RR_TM4-6 PF06459.7 ETO34611.1 - 2.4 7.9 13.4 6.5 6.5 9.1 1.9 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.9 ETO34611.1 - 3.6 5.4 12.1 5 5.0 8.4 1.2 1 0 0 1 1 1 0 CDC45-like protein NARP1 PF12569.3 ETO34611.1 - 4.9 5.7 14.4 9.8 4.7 10.0 1.6 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Ycf1 PF05758.7 ETO34618.1 - 0.04 11.6 7.8 0.049 11.3 5.4 1.3 1 0 0 1 1 1 0 Ycf1 MIP-T3 PF10243.4 ETO34618.1 - 6.5 5.1 28.9 3 6.2 17.7 1.8 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 DSPn PF14671.1 ETO34620.1 - 1.6e-33 115.6 5.4 1.6e-33 115.6 3.7 3.6 4 1 0 4 4 4 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 ETO34620.1 - 4.3e-14 52.2 0.1 2.1e-13 49.9 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 ETO34620.1 - 4.9e-06 26.0 0.0 2.1e-05 24.0 0.0 2.0 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 ETO34620.1 - 0.0087 16.3 0.3 0.026 14.7 0.0 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 ETO34620.1 - 0.0095 15.9 0.0 0.033 14.2 0.0 2.0 1 0 0 1 1 1 1 Inositol hexakisphosphate G-alpha PF00503.15 ETO34621.1 - 1.2e-62 211.8 9.6 2e-61 207.8 6.6 2.1 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO34621.1 - 2.7e-12 46.2 1.8 3.3e-06 26.4 0.0 2.8 2 1 1 3 3 3 2 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETO34621.1 - 0.02 14.8 0.1 9.1 6.2 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF3025 PF11227.3 ETO34621.1 - 0.024 14.1 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) DUF2951 PF11166.3 ETO34621.1 - 0.04 13.7 2.5 0.13 12.1 1.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) AAA_33 PF13671.1 ETO34621.1 - 0.044 13.6 0.3 0.56 10.0 0.0 2.8 3 1 0 3 3 3 0 AAA domain COesterase PF00135.23 ETO34622.1 - 6e-89 299.1 9.8 2.6e-50 171.6 3.7 2.6 2 1 0 2 2 2 2 Carboxylesterase family WD40 PF00400.27 ETO34623.1 - 6.7e-06 25.7 0.1 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 WD domain, G-beta repeat CTK3 PF12243.3 ETO34624.1 - 0.017 14.7 0.2 0.026 14.1 0.2 1.4 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 p450 PF00067.17 ETO34625.1 - 2.9e-26 92.0 0.1 5.4e-26 91.1 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 EKR PF10371.4 ETO34625.1 - 0.03 13.8 0.0 0.065 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function p450 PF00067.17 ETO34626.1 - 9.5e-10 37.5 1.6 5.4e-08 31.7 1.4 1.9 1 1 1 2 2 2 2 Cytochrome P450 Bul1_N PF04425.7 ETO34626.1 - 0.036 12.6 0.1 0.036 12.6 0.1 1.7 2 0 0 2 2 2 0 Bul1 N terminus Secretin_N_2 PF07655.8 ETO34627.1 - 0.23 11.8 7.5 0.26 11.7 5.2 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain Apis_Csd PF11671.3 ETO34627.1 - 1.4 8.7 10.6 1.5 8.6 7.3 1.1 1 0 0 1 1 1 0 Complementary sex determiner protein SMN PF06003.7 ETO34627.1 - 4.6 6.2 10.9 5.1 6.1 7.6 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) WD40 PF00400.27 ETO34628.1 - 3.8e-54 178.7 21.6 5.1e-10 38.8 0.2 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO34628.1 - 1.5e-13 49.8 3.4 5.3e-05 21.5 0.1 4.8 1 1 1 4 4 4 4 Nucleoporin Nup120/160 VEFS-Box PF09733.4 ETO34628.1 - 0.01 15.5 1.2 0.032 13.9 0.3 2.3 3 0 0 3 3 3 0 VEFS-Box of polycomb protein WD40 PF00400.27 ETO34629.1 - 4.8e-31 105.5 8.7 2.9e-11 42.7 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO34629.1 - 1.2e-07 30.2 1.2 0.037 12.1 0.0 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO34629.1 - 0.0019 17.9 0.2 0.068 12.9 0.2 2.2 1 1 1 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Kelch_6 PF13964.1 ETO34629.1 - 0.0044 17.1 1.8 3.4 8.0 0.0 3.2 2 1 1 3 3 3 2 Kelch motif DUF4221 PF13970.1 ETO34629.1 - 0.022 14.1 0.7 0.58 9.4 0.2 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4221) DUF327 PF03885.8 ETO34630.1 - 0.58 9.9 4.2 2.7 7.8 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF327) ATP-sulfurylase PF01747.12 ETO34631.1 - 2.1e-75 252.7 0.0 3.8e-75 251.9 0.0 1.4 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 ETO34631.1 - 4.7e-51 172.5 0.0 1.1e-50 171.3 0.0 1.6 2 0 0 2 2 2 1 Adenylylsulphate kinase PUA_2 PF14306.1 ETO34631.1 - 2.1e-41 141.0 0.0 3e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.1 ETO34631.1 - 2.1e-06 27.6 0.0 4.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETO34631.1 - 1.5e-05 25.3 0.0 5.4e-05 23.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 ETO34631.1 - 0.00011 22.9 0.0 0.0003 21.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 ETO34631.1 - 0.00027 20.4 0.0 0.00054 19.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain KTI12 PF08433.5 ETO34631.1 - 0.0004 19.6 0.0 0.00057 19.1 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 ABC_tran PF00005.22 ETO34631.1 - 0.0042 17.3 0.0 0.0087 16.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 ETO34631.1 - 0.0064 16.5 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.21 ETO34631.1 - 0.0068 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Zeta_toxin PF06414.7 ETO34631.1 - 0.011 14.8 0.0 0.021 13.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ArgK PF03308.11 ETO34631.1 - 0.016 13.9 0.0 0.028 13.1 0.0 1.3 1 0 0 1 1 1 0 ArgK protein DUF258 PF03193.11 ETO34631.1 - 0.027 13.6 0.0 0.048 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 ETO34631.1 - 0.03 14.2 0.0 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain CbiA PF01656.18 ETO34631.1 - 0.062 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_10 PF12846.2 ETO34631.1 - 0.064 12.6 0.1 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.1 ETO34631.1 - 0.077 13.1 0.0 0.21 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 ETO34631.1 - 0.083 13.2 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.15 ETO34631.1 - 0.11 11.1 0.1 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Thymidylate_kin PF02223.12 ETO34631.1 - 0.11 11.8 0.0 0.38 10.1 0.0 1.8 2 0 0 2 2 2 0 Thymidylate kinase MobB PF03205.9 ETO34631.1 - 0.11 12.1 0.0 0.32 10.6 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 ETO34631.1 - 0.13 11.1 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.17 ETO34631.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.1 ETO34631.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 ETO34632.1 - 9.2e-70 228.2 25.7 2.5e-12 46.1 0.3 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO34632.1 - 2.4e-12 45.7 3.0 0.031 12.4 0.0 5.6 2 2 2 5 5 5 4 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO34632.1 - 3.2e-05 24.2 3.3 3.2e-05 24.2 2.3 3.9 4 1 0 4 4 4 1 TRAF-type zinc finger TMF_DNA_bd PF12329.3 ETO34632.1 - 0.25 11.1 15.9 0.96 9.3 11.0 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding WBS_methylT PF12589.3 ETO34632.1 - 4 7.9 6.2 8.5 6.9 3.2 2.2 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome TPR_12 PF13424.1 ETO34633.1 - 0.00025 20.9 0.0 0.00049 19.9 0.0 1.4 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO34633.1 - 0.0036 16.8 1.8 1.7 8.3 0.7 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO34633.1 - 0.0047 16.5 0.2 0.012 15.2 0.1 1.7 1 1 0 1 1 1 1 TPR repeat TPR_7 PF13176.1 ETO34633.1 - 0.066 13.0 0.0 9.5 6.3 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.27 ETO34634.1 - 6.1e-57 187.5 27.0 9.5e-12 44.3 0.1 7.2 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO34634.1 - 9.3e-10 37.2 6.1 0.082 11.0 0.0 4.8 3 1 2 5 5 5 4 Nucleoporin Nup120/160 CHZ PF09649.5 ETO34634.1 - 1.7 7.9 4.8 1.7 7.9 0.5 2.6 2 0 0 2 2 2 0 Histone chaperone domain CHZ WD40 PF00400.27 ETO34635.1 - 2e-21 74.9 5.8 7.6e-11 41.4 0.1 3.0 3 0 0 3 3 3 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO34635.1 - 0.041 12.6 0.0 0.041 12.6 0.0 1.2 1 0 0 1 1 1 0 Nup133 N terminal like DUF3601 PF12208.3 ETO34635.1 - 0.11 12.4 0.3 0.21 11.5 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3601) EAF PF09816.4 ETO34636.1 - 0.00067 19.5 0.5 0.0011 18.8 0.3 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Translin PF01997.11 ETO34637.1 - 0.1 12.1 0.9 0.13 11.7 0.7 1.3 1 0 0 1 1 1 0 Translin family DUF3784 PF12650.2 ETO34637.1 - 0.17 11.8 0.8 0.35 10.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) CutA1 PF03091.10 ETO34637.1 - 0.23 11.1 2.3 0.35 10.5 0.8 1.8 1 1 0 2 2 2 0 CutA1 divalent ion tolerance protein DUF1474 PF07342.6 ETO34637.1 - 0.24 11.6 3.3 0.26 11.5 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1474) RP-C_C PF11800.3 ETO34638.1 - 0.15 11.7 7.3 0.17 11.5 5.1 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region TRAP_alpha PF03896.11 ETO34638.1 - 0.27 10.2 4.3 0.3 10.0 3.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4259 PF14078.1 ETO34638.1 - 0.32 11.5 5.0 0.44 11.0 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) TIMELESS_C PF05029.8 ETO34638.1 - 0.33 9.8 12.2 0.36 9.7 8.4 1.0 1 0 0 1 1 1 0 Timeless protein C terminal region RRN3 PF05327.6 ETO34638.1 - 1 7.4 7.4 1.1 7.2 5.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Astro_capsid PF03115.9 ETO34638.1 - 1 7.5 5.1 1.1 7.4 3.5 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor CHASE3 PF05227.8 ETO34638.1 - 1.1 8.9 6.1 1.3 8.6 4.3 1.1 1 0 0 1 1 1 0 CHASE3 domain Ycf1 PF05758.7 ETO34638.1 - 1.1 6.9 8.7 1.3 6.6 6.1 1.0 1 0 0 1 1 1 0 Ycf1 FLO_LFY PF01698.11 ETO34638.1 - 1.4 7.6 8.8 1.7 7.3 6.1 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DDHD PF02862.12 ETO34638.1 - 2.7 7.7 7.0 3 7.5 4.8 1.1 1 0 0 1 1 1 0 DDHD domain DUF342 PF03961.8 ETO34638.1 - 2.9 6.2 14.3 3 6.1 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Vfa1 PF08432.5 ETO34638.1 - 4.3 7.3 13.2 5.5 6.9 9.1 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RelA_SpoT PF04607.12 ETO34639.1 - 0.00036 20.5 1.1 0.00036 20.5 0.8 2.1 2 0 0 2 2 2 1 Region found in RelA / SpoT proteins NACHT PF05729.7 ETO34640.1 - 2.1e-10 40.4 0.0 4.5e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO34640.1 - 2.8e-05 24.4 0.1 2.8e-05 24.4 0.1 2.7 2 1 1 3 3 3 1 AAA domain AAA_17 PF13207.1 ETO34640.1 - 0.00019 22.2 0.3 0.0012 19.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETO34640.1 - 0.0023 18.0 0.0 0.0059 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 ETO34640.1 - 0.011 15.8 2.3 0.03 14.4 0.1 2.8 2 1 0 3 3 3 0 RNA helicase AAA_33 PF13671.1 ETO34640.1 - 0.11 12.4 0.0 0.42 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma_1s PF02454.11 ETO34640.1 - 0.15 11.8 2.4 1.4 8.7 0.1 2.7 2 0 0 2 2 2 0 Sigma 1s protein WD40 PF00400.27 ETO34644.1 - 9.2e-67 218.7 23.0 1.2e-13 50.3 0.2 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat PD40 PF07676.7 ETO34644.1 - 1.9e-07 30.6 2.6 4.2 7.1 0.0 7.0 8 1 0 8 8 8 2 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO34644.1 - 2.7e-05 23.1 8.2 0.32 9.6 1.2 4.1 1 1 3 4 4 4 3 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO34644.1 - 0.0003 19.1 1.6 0.065 11.5 0.1 3.1 1 1 1 3 3 3 2 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO34644.1 - 0.0032 16.5 2.4 0.82 8.7 0.0 3.7 1 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal DUF1652 PF07865.6 ETO34644.1 - 0.004 16.7 0.0 2 8.0 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1652) Ricin_B_lectin PF00652.17 ETO34644.1 - 0.095 12.7 1.4 4.7 7.2 0.0 2.9 2 2 0 2 2 2 0 Ricin-type beta-trefoil lectin domain Resistin PF06954.6 ETO34644.1 - 0.41 10.9 2.8 25 5.2 0.0 3.9 2 1 2 4 4 4 0 Resistin RPN7 PF10602.4 ETO34645.1 - 0.0076 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 RVT_1 PF00078.22 ETO34648.1 - 4.3e-33 114.4 0.2 8.6e-33 113.4 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 ETO34648.1 - 0.00021 21.3 0.0 0.00037 20.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pro_CA PF00484.14 ETO34650.1 - 0.0017 18.3 0.0 0.0029 17.6 0.0 1.3 1 0 0 1 1 1 1 Carbonic anhydrase S1FA PF04689.8 ETO34650.1 - 0.27 11.1 0.8 1.5 8.7 0.1 2.2 2 0 0 2 2 2 0 DNA binding protein S1FA Glyco_hydro_20 PF00728.17 ETO34651.1 - 3.9e-21 75.6 2.6 5.7e-21 75.0 1.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain FWWh PF14922.1 ETO34652.1 - 3.8e-06 26.5 7.7 0.00024 20.6 5.3 2.6 1 1 0 1 1 1 1 Protein of unknown function zf-RING_2 PF13639.1 ETO34654.1 - 0.016 14.9 1.3 0.068 13.0 0.0 2.2 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.1 ETO34654.1 - 0.03 14.3 0.1 0.095 12.7 0.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2672 PF10878.3 ETO34654.1 - 0.042 13.5 0.5 0.079 12.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2672) Taxilin PF09728.4 ETO34654.1 - 0.056 12.5 1.0 0.074 12.1 0.7 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein DUF2602 PF10782.4 ETO34654.1 - 0.081 12.7 1.5 7.7 6.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2602) CENP-W PF15510.1 ETO34654.1 - 0.14 12.1 0.2 0.26 11.3 0.2 1.4 1 0 0 1 1 1 0 Centromere kinetochore component W Actin PF00022.14 ETO34656.1 - 3.5e-88 295.6 0.0 3.9e-88 295.5 0.0 1.0 1 0 0 1 1 1 1 Actin Yippee-Mis18 PF03226.9 ETO34657.1 - 7.5e-10 38.7 0.7 7.5e-10 38.7 0.5 2.1 2 1 0 2 2 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF3584 PF12128.3 ETO34657.1 - 0.0006 17.3 10.0 0.00068 17.1 7.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF342 PF03961.8 ETO34657.1 - 0.00073 18.0 10.6 0.00096 17.6 7.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF342) Filament PF00038.16 ETO34657.1 - 0.001 18.5 14.6 0.0019 17.7 10.1 1.3 1 0 0 1 1 1 1 Intermediate filament protein TBPIP PF07106.8 ETO34657.1 - 0.0012 18.4 13.0 0.0012 18.4 9.0 1.7 2 0 0 2 2 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DivIC PF04977.10 ETO34657.1 - 0.003 17.0 13.9 0.12 11.9 0.2 2.3 1 1 1 2 2 2 2 Septum formation initiator AAA_27 PF13514.1 ETO34657.1 - 0.0042 14.8 6.8 0.0051 14.5 4.7 1.0 1 0 0 1 1 1 1 AAA domain DUF724 PF05266.9 ETO34657.1 - 0.0045 16.6 17.7 0.0083 15.7 12.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF724) TMF_DNA_bd PF12329.3 ETO34657.1 - 0.0076 16.0 22.1 0.0076 16.0 15.3 2.5 2 1 0 2 2 2 1 TATA element modulatory factor 1 DNA binding DUF4139 PF13598.1 ETO34657.1 - 0.0077 15.5 7.1 0.01 15.1 4.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) Seryl_tRNA_N PF02403.17 ETO34657.1 - 0.011 15.7 12.1 0.011 15.7 8.4 1.9 2 0 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain GFA PF04828.9 ETO34657.1 - 0.013 15.4 6.0 1.1 9.2 0.4 3.1 1 1 1 3 3 2 0 Glutathione-dependent formaldehyde-activating enzyme TPR_MLP1_2 PF07926.7 ETO34657.1 - 0.014 15.1 17.3 0.033 13.9 12.0 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein zf-C4H2 PF10146.4 ETO34657.1 - 0.022 14.8 10.8 0.03 14.3 7.5 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein IncA PF04156.9 ETO34657.1 - 0.031 13.8 17.5 0.16 11.5 12.1 1.9 1 1 0 1 1 1 0 IncA protein zf-HYPF PF07503.7 ETO34657.1 - 0.046 13.1 1.7 1.8 8.0 0.0 2.4 2 0 0 2 2 2 0 HypF finger Lebercilin PF15619.1 ETO34657.1 - 0.064 12.6 16.9 0.14 11.5 11.7 1.5 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Lipoprotein_20 PF13942.1 ETO34657.1 - 0.073 12.6 6.1 0.11 12.0 4.3 1.2 1 0 0 1 1 1 0 YfhG lipoprotein OmpH PF03938.9 ETO34657.1 - 0.087 12.7 12.5 0.15 12.0 8.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Spc7 PF08317.6 ETO34657.1 - 0.13 10.8 19.0 0.13 10.8 12.7 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein LXG PF04740.7 ETO34657.1 - 0.2 11.4 13.0 5.1 6.8 9.3 2.3 1 1 0 1 1 1 0 LXG domain of WXG superfamily ERM PF00769.14 ETO34657.1 - 0.24 10.8 25.7 0.45 10.0 17.8 1.3 1 1 0 1 1 1 0 Ezrin/radixin/moesin family GAS PF13851.1 ETO34657.1 - 0.25 10.4 22.4 0.35 10.0 8.7 2.1 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.6 ETO34657.1 - 0.26 10.7 17.1 1.1 8.6 11.8 2.0 1 1 0 1 1 1 0 Phage minor structural protein GP20 Kinesin-relat_1 PF12711.2 ETO34657.1 - 0.26 11.6 15.5 0.81 10.1 8.8 2.7 2 1 0 2 2 2 0 Kinesin motor HAUS-augmin3 PF14932.1 ETO34657.1 - 0.28 10.3 19.8 0.1 11.7 11.7 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 AAA_13 PF13166.1 ETO34657.1 - 0.32 9.4 17.4 0.15 10.4 10.4 1.5 1 1 0 1 1 1 0 AAA domain DUF4140 PF13600.1 ETO34657.1 - 0.33 11.4 11.7 1 9.8 0.5 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) APG6 PF04111.7 ETO34657.1 - 0.37 9.7 24.2 0.93 8.4 16.7 1.7 1 1 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 ETO34657.1 - 0.39 8.4 11.7 0.48 8.2 8.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Med4 PF10018.4 ETO34657.1 - 0.43 9.9 15.7 0.21 10.9 2.0 2.3 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Casc1 PF12366.3 ETO34657.1 - 0.47 9.9 10.3 0.77 9.2 7.1 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 TEX13 PF15186.1 ETO34657.1 - 0.47 10.0 8.9 0.89 9.1 6.2 1.5 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family MscS_porin PF12795.2 ETO34657.1 - 0.47 9.7 16.1 0.018 14.3 7.2 1.4 2 0 0 2 2 1 0 Mechanosensitive ion channel porin domain Tweety PF04906.8 ETO34657.1 - 0.58 8.5 4.8 0.92 7.8 3.3 1.2 1 0 0 1 1 1 0 Tweety DUF4618 PF15397.1 ETO34657.1 - 0.58 9.4 18.3 5 6.3 4.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Ax_dynein_light PF10211.4 ETO34657.1 - 0.74 9.6 16.1 1.6 8.4 11.1 1.6 1 0 0 1 1 1 0 Axonemal dynein light chain DUF1664 PF07889.7 ETO34657.1 - 0.75 9.5 9.4 1.1 9.1 5.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CCDC155 PF14662.1 ETO34657.1 - 0.82 9.2 21.3 0.74 9.3 14.0 1.4 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 IFT57 PF10498.4 ETO34657.1 - 0.95 8.1 20.4 0.33 9.6 12.1 1.6 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 CorA PF01544.13 ETO34657.1 - 1.2 8.1 4.5 1.1 8.2 0.6 1.9 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF4510 PF14971.1 ETO34657.1 - 1.4 9.0 7.7 2.3 8.3 4.9 1.7 1 1 1 2 2 1 0 Domain of unknown function (DUF4510) FlaC_arch PF05377.6 ETO34657.1 - 1.5 8.8 17.4 1.9 8.4 0.9 3.5 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) DUF3450 PF11932.3 ETO34657.1 - 1.8 7.7 16.1 1.4 8.1 10.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4200 PF13863.1 ETO34657.1 - 1.8 8.5 21.4 5.4 6.9 6.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) AAA_11 PF13086.1 ETO34657.1 - 1.9 8.0 13.7 0.86 9.1 7.9 1.5 1 1 0 1 1 1 0 AAA domain Prefoldin_2 PF01920.15 ETO34657.1 - 1.9 8.2 22.8 6.2 6.6 3.9 2.5 1 1 1 2 2 2 0 Prefoldin subunit DUF2968 PF11180.3 ETO34657.1 - 2.1 7.6 14.2 13 5.1 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) CENP-F_leu_zip PF10473.4 ETO34657.1 - 2.1 8.1 26.8 1.1 9.0 16.4 2.2 2 1 1 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MMPL PF03176.10 ETO34657.1 - 2.2 6.9 3.7 2.8 6.5 2.5 1.2 1 0 0 1 1 1 0 MMPL family Reo_sigmaC PF04582.7 ETO34657.1 - 2.3 7.3 15.6 11 5.0 10.7 1.9 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Glyco_hydro_67N PF03648.9 ETO34657.1 - 2.3 8.2 6.4 1 9.4 1.6 2.2 1 1 1 2 2 2 0 Glycosyl hydrolase family 67 N-terminus DegS PF05384.6 ETO34657.1 - 2.8 7.1 15.8 3.6 6.7 4.6 2.2 1 1 1 2 2 2 0 Sensor protein DegS Occludin_ELL PF07303.8 ETO34657.1 - 3.2 8.5 12.3 44 4.8 8.3 2.2 1 1 1 2 2 2 0 Occludin homology domain Tup_N PF08581.5 ETO34657.1 - 3.4 7.9 14.0 0.77 9.9 5.6 2.3 1 1 0 2 2 2 0 Tup N-terminal Cep57_CLD_2 PF14197.1 ETO34657.1 - 3.8 7.5 17.7 8.9e+02 -0.1 12.3 2.4 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 DivIVA PF05103.8 ETO34657.1 - 4.4 7.3 22.2 1.1 9.2 12.7 1.9 1 1 1 2 2 2 0 DivIVA protein DUF730 PF05325.6 ETO34657.1 - 4.8 7.0 10.2 5 6.9 3.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF730) DUF3166 PF11365.3 ETO34657.1 - 5.1 7.6 13.9 1.7 9.1 3.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) Laminin_II PF06009.7 ETO34657.1 - 5.7 6.6 17.8 0.13 11.9 7.8 1.5 2 0 0 2 2 1 0 Laminin Domain II DUF972 PF06156.8 ETO34657.1 - 7 7.0 23.0 1 9.7 11.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Mnd1 PF03962.10 ETO34657.1 - 7.3 6.2 20.1 9.1 5.8 13.3 1.6 1 1 0 1 1 1 0 Mnd1 family DUF641 PF04859.7 ETO34657.1 - 7.4 6.3 14.4 0.95 9.2 4.7 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) COG2 PF06148.6 ETO34657.1 - 8.1 6.3 14.0 2.2 8.1 0.7 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CENP-Q PF13094.1 ETO34657.1 - 9.3 6.2 22.8 27 4.7 15.8 1.8 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit FrhB_FdhB_C PF04432.8 ETO34657.1 - 9.4 5.6 10.1 78 2.6 5.7 2.6 1 1 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus ELO PF01151.13 ETO34658.1 - 1.7e-21 76.6 19.2 2.5e-19 69.5 6.1 2.8 1 1 2 3 3 3 2 GNS1/SUR4 family CBS PF00571.23 ETO34659.1 - 0.00041 20.0 0.0 0.0016 18.2 0.0 1.9 1 1 0 1 1 1 1 CBS domain CDC27 PF09507.5 ETO34660.1 - 0.08 12.1 37.2 0.11 11.6 25.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Med19 PF10278.4 ETO34660.1 - 1.2 8.7 39.4 0.039 13.6 11.3 2.2 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 ORC6 PF05460.8 ETO34660.1 - 3.8 6.5 22.2 5.3 6.0 15.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Peptidase_S49_N PF08496.5 ETO34660.1 - 4.8 6.9 30.1 2.3 8.0 6.5 3.3 3 0 0 3 3 3 0 Peptidase family S49 N-terminal WD40 PF00400.27 ETO34661.1 - 1e-24 85.4 0.1 1.3e-09 37.5 0.0 3.3 3 1 0 3 3 3 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO34661.1 - 0.0023 16.7 0.3 0.28 9.8 0.0 2.1 1 1 1 2 2 2 2 Nup133 N terminal like Nup160 PF11715.3 ETO34661.1 - 0.013 13.6 0.1 0.45 8.5 0.0 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 DUF977 PF06163.6 ETO34662.1 - 0.03 14.0 0.2 0.046 13.4 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) Cys_rich_FGFR PF00839.12 ETO34663.1 - 0.11 12.4 0.2 6.5 6.7 0.0 2.5 2 0 0 2 2 2 0 Cysteine rich repeat DUF3944 PF13099.1 ETO34663.1 - 0.14 11.7 0.9 3.1 7.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3944) CLASP_N PF12348.3 ETO34664.1 - 9.1e-05 21.9 0.5 0.00016 21.0 0.3 1.4 1 1 0 1 1 1 1 CLASP N terminal HEAT_2 PF13646.1 ETO34664.1 - 0.0026 18.0 0.0 0.074 13.3 0.0 2.1 1 1 1 2 2 2 1 HEAT repeats HEAT PF02985.17 ETO34664.1 - 0.012 15.5 0.0 0.074 13.1 0.0 2.3 2 0 0 2 2 2 0 HEAT repeat HEAT_EZ PF13513.1 ETO34664.1 - 0.14 12.7 0.0 0.37 11.3 0.0 1.8 2 1 0 2 2 2 0 HEAT-like repeat Dopey_N PF04118.9 ETO34664.1 - 0.18 10.5 4.0 1.6 7.4 0.1 2.1 1 1 1 2 2 2 0 Dopey, N-terminal MMS19_C PF12460.3 ETO34664.1 - 0.23 10.1 4.6 0.67 8.6 3.1 1.7 1 1 1 2 2 2 0 RNAPII transcription regulator C-terminal DUF842 PF05811.8 ETO34664.1 - 0.45 9.9 9.0 0.11 11.9 3.2 2.0 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF842) WD40 PF00400.27 ETO34665.1 - 1.1e-37 126.5 6.5 1.4e-11 43.8 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO34665.1 - 1.1e-05 23.9 0.2 0.42 8.8 0.0 3.5 1 1 3 4 4 4 4 Cytochrome D1 heme domain DUF3312 PF11768.3 ETO34665.1 - 0.01 14.0 0.1 2.6 6.1 0.0 3.2 1 1 2 4 4 4 0 Protein of unknown function (DUF3312) PD40 PF07676.7 ETO34665.1 - 0.043 13.4 9.6 13 5.5 0.1 5.0 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat G-alpha PF00503.15 ETO34666.1 - 9.1e-34 116.7 1.5 1e-33 116.5 1.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit DUF1189 PF06691.6 ETO34666.1 - 0.019 14.2 0.3 0.022 14.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) G-alpha PF00503.15 ETO34667.1 - 2e-61 207.8 2.2 5e-61 206.5 1.5 1.5 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO34667.1 - 2.8e-11 42.9 0.8 5.9e-08 32.1 0.1 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 ETO34667.1 - 0.00065 20.1 0.4 0.049 14.1 0.0 2.7 2 1 1 3 3 3 1 Miro-like protein TPR_12 PF13424.1 ETO34668.1 - 1.4e-25 89.0 0.1 1.4e-12 47.3 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO34668.1 - 9.8e-12 43.9 1.1 2.1e-10 39.7 0.5 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO34668.1 - 1.1e-11 43.6 2.4 1.1e-07 31.1 0.4 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO34668.1 - 5.1e-11 42.0 0.0 8.4e-11 41.3 0.0 1.4 1 0 0 1 1 1 1 TPR repeat TPR_10 PF13374.1 ETO34668.1 - 5.4e-11 42.0 0.0 1.2e-08 34.5 0.0 3.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO34668.1 - 6e-11 41.3 0.4 1.3e-07 30.9 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO34668.1 - 6.6e-11 41.1 0.1 8.7e-08 31.4 0.0 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO34668.1 - 1.1e-06 28.7 0.1 0.056 13.9 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO34668.1 - 7e-06 25.8 0.1 0.00024 21.0 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_3 PF07720.7 ETO34668.1 - 0.00063 19.4 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO34668.1 - 0.0061 17.2 0.0 0.021 15.5 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.13 ETO34668.1 - 0.0069 16.2 0.4 0.016 15.0 0.3 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain SNAP PF14938.1 ETO34668.1 - 0.021 14.0 0.0 0.023 13.8 0.0 1.1 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP SHNi-TPR PF10516.4 ETO34668.1 - 0.035 13.3 0.0 0.16 11.2 0.0 2.0 2 0 0 2 2 2 0 SHNi-TPR WD40 PF00400.27 ETO34669.1 - 4.1e-08 32.7 13.8 1.7e-05 24.5 0.0 4.5 5 1 0 5 5 5 2 WD domain, G-beta repeat Integrase_DNA PF02920.10 ETO34669.1 - 0.021 14.2 0.3 2 7.8 0.1 2.6 2 0 0 2 2 2 0 DNA binding domain of tn916 integrase Secretin_N_2 PF07655.8 ETO34669.1 - 5.8 7.3 24.6 0.62 10.4 4.6 3.6 3 0 0 3 3 3 0 Secretin N-terminal domain IncA PF04156.9 ETO34670.1 - 0.009 15.6 2.0 0.011 15.3 0.3 1.9 1 1 1 2 2 2 1 IncA protein BTV_NS2 PF04514.7 ETO34670.1 - 0.12 11.2 2.6 0.14 11.0 1.8 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF4611 PF15387.1 ETO34670.1 - 0.35 11.0 8.1 1.1 9.4 5.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) DUF3810 PF12725.2 ETO34670.1 - 0.45 9.3 7.1 0.15 10.9 2.7 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3810) DivIC PF04977.10 ETO34670.1 - 8.3 5.9 8.5 0.21 11.0 0.5 2.5 2 1 0 2 2 2 0 Septum formation initiator WD40 PF00400.27 ETO34671.1 - 2e-41 138.4 12.0 4.1e-11 42.3 0.2 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat PD40 PF07676.7 ETO34671.1 - 2.2e-07 30.3 6.2 0.019 14.5 0.1 4.2 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO34671.1 - 2.8e-06 25.7 1.2 0.007 14.5 0.1 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO34671.1 - 1.2e-05 25.1 0.1 6.5e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Resistin PF06954.6 ETO34671.1 - 0.0019 18.4 0.2 7.4 6.9 0.0 3.4 1 1 2 3 3 3 1 Resistin Nucleoporin_N PF08801.6 ETO34671.1 - 0.0033 16.2 1.5 0.75 8.4 0.0 2.7 1 1 2 3 3 3 2 Nup133 N terminal like DUF3601 PF12208.3 ETO34671.1 - 0.051 13.5 0.2 0.37 10.7 0.0 2.4 3 1 0 3 3 3 0 Domain of unknown function (DUF3601) FtsX PF02687.16 ETO34673.1 - 2.3e-19 69.3 10.2 3.6e-19 68.6 7.1 1.2 1 0 0 1 1 1 1 FtsX-like permease family YjgP_YjgQ PF03739.9 ETO34673.1 - 0.00052 18.8 4.8 0.00052 18.8 3.3 1.7 1 1 0 2 2 2 1 Predicted permease YjgP/YjgQ family NfeD PF01957.13 ETO34673.1 - 7.9 6.6 8.4 1.4 9.0 2.6 1.9 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding DUF1435 PF07256.7 ETO34674.1 - 0.32 11.0 1.9 2.3 8.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) Pkinase PF00069.20 ETO34675.1 - 2.3e-06 26.9 0.5 3.6e-06 26.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO34675.1 - 0.0074 15.3 0.9 0.0086 15.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Endonuc_Holl PF10107.4 ETO34675.1 - 0.17 11.5 1.9 0.31 10.7 1.3 1.5 1 1 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Pkinase PF00069.20 ETO34676.1 - 7.9e-33 113.6 0.1 1.9e-22 79.7 0.2 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO34676.1 - 1.3e-11 44.1 0.1 9.2e-10 38.0 0.1 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 ETO34676.1 - 4.1e-06 26.0 0.1 6e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETO34676.1 - 2e-05 23.7 0.0 0.023 13.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 ETO34676.1 - 0.0042 16.8 0.1 0.009 15.7 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 ETO34676.1 - 0.0064 15.8 0.1 0.013 14.8 0.1 1.5 2 0 0 2 2 2 1 RIO1 family PIP49_C PF12260.3 ETO34676.1 - 0.047 13.1 0.3 0.13 11.6 0.1 1.7 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 YukC PF10140.4 ETO34676.1 - 0.061 11.8 0.0 0.084 11.4 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC DUF1762 PF08574.5 ETO34676.1 - 0.088 13.2 0.1 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1762) Pox_ser-thr_kin PF05445.6 ETO34676.1 - 0.096 11.4 3.2 1.9 7.2 0.1 2.8 2 1 1 3 3 3 0 Poxvirus serine/threonine protein kinase TryThrA_C PF12319.3 ETO34677.1 - 0.21 10.7 11.9 0.4 9.8 7.2 2.0 1 1 0 2 2 2 0 Tryptophan-Threonine-rich plasmodium antigen C terminal RNase_H PF00075.19 ETO34681.1 - 0.00027 21.3 0.4 0.045 14.0 0.0 2.9 3 0 0 3 3 3 2 RNase H DUF619 PF04768.8 ETO34682.1 - 0.11 11.9 1.7 0.2 11.0 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF619) DUF2264 PF10022.4 ETO34683.1 - 0.017 13.8 1.1 0.022 13.4 0.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) HEAT_2 PF13646.1 ETO34686.1 - 4.6e-18 65.2 0.0 0.016 15.5 0.0 7.2 5 2 2 7 7 7 4 HEAT repeats HEAT PF02985.17 ETO34686.1 - 3.6e-15 54.5 0.1 0.0029 17.5 0.0 9.1 9 0 0 9 9 9 2 HEAT repeat Ank_2 PF12796.2 ETO34686.1 - 1.2e-12 47.9 0.5 2.9e-11 43.5 0.0 3.6 3 1 1 4 4 4 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO34686.1 - 5.6e-11 41.5 0.6 6.7e-05 22.7 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat HEAT_EZ PF13513.1 ETO34686.1 - 9.4e-11 41.8 0.0 4.4 7.9 0.0 7.1 6 2 2 8 8 8 3 HEAT-like repeat Ank PF00023.25 ETO34686.1 - 3.6e-10 39.1 0.1 1.8e-06 27.4 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 ETO34686.1 - 7.1e-09 35.9 0.4 8.6e-08 32.4 0.1 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO34686.1 - 5e-07 29.7 0.2 2.3e-05 24.4 0.1 3.4 2 1 1 3 3 3 1 Ankyrin repeats (many copies) TIP120 PF08623.5 ETO34686.1 - 0.0012 18.5 27.4 1.5 8.3 0.2 8.1 5 3 3 8 8 8 3 TATA-binding protein interacting (TIP20) UME PF08064.8 ETO34686.1 - 0.014 15.3 5.5 0.099 12.6 0.0 4.8 7 0 0 7 7 7 0 UME (NUC010) domain Kelch_1 PF01344.20 ETO34687.1 - 2e-07 30.4 4.9 0.00012 21.5 0.4 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO34687.1 - 0.00023 21.1 3.9 0.13 12.4 0.2 4.2 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 ETO34687.1 - 0.0018 18.3 0.3 0.033 14.3 0.0 3.2 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO34687.1 - 0.13 12.0 5.1 0.24 11.2 0.2 3.7 4 1 0 4 4 4 0 Kelch motif Kelch_4 PF13418.1 ETO34687.1 - 0.54 10.0 6.0 0.99 9.2 0.1 3.9 4 1 1 5 5 5 0 Galactose oxidase, central domain WD40 PF00400.27 ETO34688.1 - 1.7e-36 122.7 8.9 6e-13 48.1 0.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO34688.1 - 2.7e-10 39.0 2.3 0.00034 18.8 0.3 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 DUF1914 PF08932.5 ETO34688.1 - 3.7 7.6 6.4 15 5.6 0.2 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1914) HEAT_2 PF13646.1 ETO34689.1 - 6.9e-27 93.5 0.0 3.5e-09 36.8 0.0 4.6 1 1 4 5 5 5 4 HEAT repeats HEAT PF02985.17 ETO34689.1 - 3.5e-24 82.6 0.0 0.0018 18.1 0.0 8.2 8 0 0 8 8 7 4 HEAT repeat HEAT_EZ PF13513.1 ETO34689.1 - 3e-11 43.4 0.0 0.0063 16.9 0.0 4.8 5 0 0 5 5 5 3 HEAT-like repeat CLASP_N PF12348.3 ETO34689.1 - 5.5e-10 39.0 2.4 0.00016 21.0 0.1 2.9 1 1 1 2 2 2 2 CLASP N terminal DUF2435 PF10363.4 ETO34689.1 - 1.3e-07 31.4 1.0 0.022 14.6 0.0 4.5 2 1 3 5 5 5 2 Protein of unknown function (DUF2435) Cnd1 PF12717.2 ETO34689.1 - 4.8e-07 29.7 7.5 6.5e-07 29.3 2.5 2.8 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 ETO34689.1 - 2.1e-06 27.9 4.8 0.43 10.9 0.0 5.0 1 1 5 6 6 6 3 Vacuolar 14 Fab1-binding region TIP120 PF08623.5 ETO34689.1 - 3.6e-05 23.3 10.7 0.2 11.2 0.1 5.4 1 1 4 5 5 5 3 TATA-binding protein interacting (TIP20) DUF3554 PF12074.3 ETO34689.1 - 0.00054 19.4 4.1 0.037 13.4 0.1 3.3 1 1 0 2 2 2 1 Domain of unknown function (DUF3554) V-ATPase_H_N PF03224.9 ETO34689.1 - 0.0012 18.0 4.1 0.06 12.4 0.4 2.7 1 1 1 2 2 2 2 V-ATPase subunit H DUF2608 PF11019.3 ETO34689.1 - 0.0019 17.2 2.8 0.5 9.3 0.1 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF2608) HEAT_PBS PF03130.11 ETO34689.1 - 0.0031 17.8 0.0 8.5 7.1 0.0 4.7 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat TAN PF11640.3 ETO34689.1 - 0.0065 16.2 6.8 0.0084 15.8 1.0 3.7 1 1 1 2 2 2 2 Telomere-length maintenance and DNA damage repair DUF4428 PF14471.1 ETO34689.1 - 0.022 14.4 10.2 0.41 10.4 0.4 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4428) HNH_5 PF14279.1 ETO34689.1 - 0.064 13.2 8.1 0.21 11.6 0.4 3.7 2 1 2 4 4 4 0 HNH endonuclease Spore_III_AB PF09548.5 ETO34689.1 - 0.095 12.4 3.9 0.73 9.5 0.8 3.5 1 1 2 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) DUF3385 PF11865.3 ETO34689.1 - 0.16 11.9 0.8 22 4.9 0.1 3.3 2 2 0 2 2 2 0 Domain of unknown function (DUF3385) UME PF08064.8 ETO34689.1 - 0.44 10.5 4.6 0.37 10.7 0.1 3.1 3 1 1 4 4 4 0 UME (NUC010) domain gag_pre-integrs PF13976.1 ETO34689.1 - 0.89 9.2 8.0 13 5.5 0.1 4.0 4 0 0 4 4 4 0 GAG-pre-integrase domain DUF2758 PF10957.3 ETO34689.1 - 4 7.3 7.5 54 3.7 0.0 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2758) Dsh_C PF12316.3 ETO34690.1 - 2.6 8.1 11.0 3.8 7.5 7.6 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Ribosomal_L3 PF00297.17 ETO34691.1 - 1.6e-67 227.6 15.3 8.4e-50 169.5 0.9 2.5 3 0 0 3 3 3 2 Ribosomal protein L3 Tom37_C PF11801.3 ETO34691.1 - 0.38 10.6 7.0 0.96 9.2 4.8 1.6 1 0 0 1 1 1 0 Tom37 C-terminal domain Trypan_PARP PF05887.6 ETO34691.1 - 9 6.1 8.2 17 5.2 5.7 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Kelch_5 PF13854.1 ETO34692.1 - 0.051 13.5 0.1 2 8.4 0.0 2.3 2 0 0 2 2 2 0 Kelch motif Pox_F12L PF03337.8 ETO34692.1 - 0.055 11.3 0.0 0.07 11.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus F12L protein Copper-bind PF00127.15 ETO34692.1 - 0.12 12.5 1.4 0.14 12.3 0.1 1.7 2 0 0 2 2 2 0 Copper binding proteins, plastocyanin/azurin family DUF4518 PF15008.1 ETO34692.1 - 0.34 9.8 5.4 0.11 11.4 0.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4518) SEA PF01390.15 ETO34692.1 - 1.1 8.9 4.3 0.27 10.9 0.4 1.8 2 0 0 2 2 2 0 SEA domain DED PF01335.16 ETO34693.1 - 0.87 9.7 4.6 1.9 8.6 0.1 2.6 2 0 0 2 2 2 0 Death effector domain Mt_ATP-synt_B PF05405.9 ETO34693.1 - 7.2 6.0 15.8 5.7 6.3 5.9 2.5 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) CLTH PF10607.4 ETO34694.1 - 2.3e-14 53.2 7.0 2.3e-14 53.2 4.8 1.9 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain Beach PF02138.13 ETO34695.1 - 8.2e-104 346.8 0.1 1.6e-103 345.8 0.1 1.5 1 0 0 1 1 1 1 Beige/BEACH domain FYVE PF01363.16 ETO34695.1 - 1.1e-19 70.0 9.3 2.1e-19 69.1 6.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger PH_BEACH PF14844.1 ETO34695.1 - 3.4e-15 55.7 0.1 7.1e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 ETO34695.1 - 4.1e-10 39.1 8.9 3.9e-09 36.0 0.1 4.4 5 0 0 5 5 5 1 WD domain, G-beta repeat IBR PF01485.16 ETO34695.1 - 0.043 13.6 5.3 0.12 12.2 3.7 1.7 1 0 0 1 1 1 0 IBR domain FYVE_2 PF02318.11 ETO34695.1 - 0.052 13.4 6.6 0.14 12.0 4.6 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Ribosomal_S27e PF01667.12 ETO34695.1 - 0.093 12.2 5.1 5.7 6.5 0.0 2.7 2 0 0 2 2 2 0 Ribosomal protein S27 zf-RING_5 PF14634.1 ETO34695.1 - 1.2 8.9 10.5 2.4 7.9 7.3 1.6 1 0 0 1 1 1 0 zinc-RING finger domain G-alpha PF00503.15 ETO34697.1 - 1.1e-56 192.2 2.1 1.6e-56 191.6 1.5 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO34697.1 - 2.1e-06 27.1 0.2 0.0072 15.5 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Rad17 PF03215.10 ETO34697.1 - 0.0038 15.9 0.0 0.0072 15.0 0.0 1.4 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_29 PF13555.1 ETO34697.1 - 0.067 12.7 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 ETO34697.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 ETO34697.1 - 0.18 12.1 0.3 0.31 11.3 0.2 1.5 1 1 0 1 1 1 0 ABC transporter WD40 PF00400.27 ETO34699.1 - 3.6e-19 67.8 9.8 1.3e-10 40.7 0.4 3.4 3 1 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO34699.1 - 0.0074 14.4 0.1 2 6.4 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO34699.1 - 0.011 14.0 0.0 0.015 13.6 0.0 1.1 1 0 0 1 1 1 0 Cytochrome D1 heme domain TPR_12 PF13424.1 ETO34700.1 - 1.9e-52 175.1 3.3 3.7e-21 74.8 0.0 4.0 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO34700.1 - 3.8e-19 67.9 0.0 4.1e-06 26.5 0.0 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO34700.1 - 4.8e-18 64.5 4.4 6e-08 32.2 0.0 3.1 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 ETO34700.1 - 9.4e-15 53.5 17.3 8.6e-07 28.3 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO34700.1 - 1.5e-13 49.5 7.6 0.0015 18.3 0.0 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO34700.1 - 2.9e-12 45.3 1.0 0.088 12.6 0.0 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO34700.1 - 7.1e-09 34.8 19.7 0.00014 21.4 0.1 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO34700.1 - 1.4e-06 27.9 1.7 0.096 12.9 0.0 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO34700.1 - 0.0042 17.7 0.0 0.91 10.2 0.0 2.5 2 1 1 3 3 2 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO34700.1 - 0.024 14.7 4.0 0.067 13.3 1.7 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETO34700.1 - 0.072 13.5 0.2 17 6.1 0.2 3.7 4 1 0 4 4 3 0 Tetratricopeptide repeat Ten1 PF12658.2 ETO34700.1 - 0.082 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Telomere capping, CST complex subunit MIT PF04212.13 ETO34700.1 - 3.7 7.4 10.9 3.2 7.6 0.2 4.0 5 2 1 6 6 6 0 MIT (microtubule interacting and transport) domain WD40 PF00400.27 ETO34701.1 - 1.6e-62 205.2 22.7 5.9e-11 41.8 0.4 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO34701.1 - 2.5e-12 45.7 0.8 0.0018 16.5 0.0 4.9 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO34701.1 - 0.0023 16.7 12.0 0.94 8.1 0.0 4.9 2 1 2 4 4 4 4 Nup133 N terminal like MUG2_C PF08593.5 ETO34702.1 - 0.037 14.2 1.0 0.12 12.5 0.4 2.2 2 0 0 2 2 2 0 Meiotically up-regulated glycoproteins C-terminal BBS2_C PF14782.1 ETO34702.1 - 0.1 11.1 0.1 0.14 10.6 0.1 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal DivIVA PF05103.8 ETO34702.1 - 0.11 12.4 3.6 0.21 11.6 2.5 1.4 1 0 0 1 1 1 0 DivIVA protein MBD_C PF14048.1 ETO34702.1 - 6.3 7.4 9.1 21 5.7 0.2 3.2 2 1 1 3 3 3 0 C-terminal domain of methyl-CpG binding protein 2 and 3 SAM_1 PF00536.25 ETO34703.1 - 0.002 18.2 0.6 0.0053 16.8 0.4 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) NEMO PF11577.3 ETO34703.1 - 0.0024 17.5 1.2 0.0048 16.6 0.8 1.5 1 0 0 1 1 1 1 NF-kappa-B essential modulator NEMO DivIVA PF05103.8 ETO34703.1 - 0.0059 16.6 2.3 0.0059 16.6 1.6 1.7 2 0 0 2 2 2 1 DivIVA protein DUF3226 PF11536.3 ETO34703.1 - 0.0061 16.0 0.1 0.0079 15.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3226) DUF972 PF06156.8 ETO34703.1 - 0.013 15.8 1.0 0.041 14.2 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) AAA_27 PF13514.1 ETO34703.1 - 0.027 12.1 0.3 0.034 11.8 0.2 1.1 1 0 0 1 1 1 0 AAA domain DUF3972 PF13118.1 ETO34703.1 - 0.027 14.5 0.3 0.027 14.5 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) PepSY PF03413.14 ETO34703.1 - 0.039 14.5 0.5 0.082 13.5 0.3 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain NAD_binding_5 PF07994.7 ETO34703.1 - 0.07 12.6 0.5 0.098 12.1 0.4 1.2 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase IFP_35_N PF07334.8 ETO34703.1 - 0.086 12.8 4.5 0.21 11.6 3.1 1.6 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus SAM_2 PF07647.12 ETO34703.1 - 0.11 12.3 0.8 0.26 11.1 0.6 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Mto2_bdg PF12808.2 ETO34703.1 - 0.15 12.2 0.7 0.15 12.2 0.5 1.9 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF2681 PF10883.3 ETO34703.1 - 0.3 11.3 7.0 0.061 13.5 2.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Snf7 PF03357.16 ETO34703.1 - 0.47 9.8 6.5 0.039 13.3 1.4 1.5 2 0 0 2 2 2 0 Snf7 Leu_zip PF15294.1 ETO34703.1 - 0.6 9.1 6.6 1.3 8.0 3.9 1.7 1 1 0 1 1 1 0 Leucine zipper Speriolin_N PF15058.1 ETO34703.1 - 4.7 7.0 5.1 6.4 6.6 1.6 2.2 2 1 0 2 2 1 0 Speriolin N terminus SAM_1 PF00536.25 ETO34704.1 - 5.8e-09 35.9 2.3 9.8e-09 35.2 0.2 2.5 2 1 1 3 3 3 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO34704.1 - 1.4e-08 34.4 0.2 3.6e-08 33.1 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) ARGLU PF15346.1 ETO34704.1 - 0.019 14.7 0.5 0.019 14.7 0.3 3.3 2 1 1 3 3 3 0 Arginine and glutamate-rich 1 DUF733 PF05306.6 ETO34705.1 - 1.7 8.9 11.2 0.5 10.6 4.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF733) PP2C_C PF07830.8 ETO34705.1 - 7.5 6.7 6.5 8.3 6.6 0.2 3.1 2 1 2 4 4 4 0 Protein serine/threonine phosphatase 2C, C-terminal domain Gag_spuma PF03276.9 ETO34706.1 - 0.01 14.2 0.2 0.015 13.6 0.1 1.3 1 0 0 1 1 1 0 Spumavirus gag protein ABC_tran_2 PF12848.2 ETO34706.1 - 0.023 14.5 0.7 0.09 12.6 0.5 2.1 1 0 0 1 1 1 0 ABC transporter HemX PF04375.9 ETO34706.1 - 0.058 11.9 5.2 0.1 11.1 3.6 1.3 1 0 0 1 1 1 0 HemX DUF1515 PF07439.6 ETO34706.1 - 0.085 12.6 0.6 0.21 11.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) ORF6C PF10552.4 ETO34706.1 - 0.85 9.3 8.2 1.2 8.8 1.2 3.1 2 1 1 3 3 3 0 ORF6C domain DivIC PF04977.10 ETO34706.1 - 3 7.3 6.8 0.92 9.0 1.9 2.3 2 1 0 2 2 2 0 Septum formation initiator CAP PF00188.21 ETO34707.1 - 5.3e-13 49.5 11.8 5.3e-13 49.5 8.2 2.7 2 1 0 2 2 2 1 Cysteine-rich secretory protein family TMEM154 PF15102.1 ETO34707.1 - 1.3 8.7 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 TMEM154 protein family RF-1 PF00472.15 ETO34708.1 - 1.1e-15 57.4 0.7 1.1e-15 57.4 0.5 1.5 1 1 1 2 2 2 1 RF-1 domain FKBP_C PF00254.23 ETO34708.1 - 0.0041 17.1 0.1 0.15 12.0 0.0 2.3 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase DDE_Tnp_2 PF04693.7 ETO34708.1 - 0.11 11.4 4.0 0.58 9.1 0.5 2.4 2 1 1 3 3 3 0 Archaeal putative transposase ISC1217 YMF19 PF02326.10 ETO34709.1 - 0.034 14.7 3.5 0.034 14.7 2.4 2.3 1 1 1 2 2 2 0 Plant ATP synthase F0 Ly49 PF08391.5 ETO34709.1 - 0.056 13.5 3.8 0.088 12.9 2.6 1.3 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Hepcidin PF06446.7 ETO34710.1 - 0.033 14.5 1.5 0.085 13.2 0.3 2.2 2 0 0 2 2 2 0 Hepcidin SNAP-25 PF00835.14 ETO34711.1 - 0.22 12.3 2.4 0.4 11.5 0.3 2.2 1 1 1 2 2 2 0 SNAP-25 family Gal_Lectin PF02140.13 ETO34712.1 - 5.9e-16 58.5 1.9 5.9e-16 58.5 1.3 1.7 2 0 0 2 2 2 1 Galactose binding lectin domain Glyco_hydro_39 PF01229.12 ETO34712.1 - 0.00029 19.3 1.0 0.00051 18.5 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 HEAT PF02985.17 ETO34713.1 - 6.5e-09 35.1 0.5 3.4e-06 26.6 0.0 3.9 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 ETO34713.1 - 1.1e-07 32.1 0.0 3.6e-06 27.2 0.0 3.4 4 0 0 4 4 4 1 HEAT-like repeat HEAT_2 PF13646.1 ETO34713.1 - 7.1e-07 29.4 0.0 1.4e-05 25.3 0.0 2.5 1 1 1 2 2 2 1 HEAT repeats Adaptin_N PF01602.15 ETO34713.1 - 9e-05 20.9 1.4 0.0045 15.3 0.0 2.7 3 0 0 3 3 3 2 Adaptin N terminal region Speriolin_C PF15059.1 ETO34713.1 - 0.01 15.8 0.1 0.031 14.2 0.0 1.8 1 0 0 1 1 1 0 Speriolin C-terminus Arm PF00514.18 ETO34713.1 - 0.054 13.3 0.0 1.1 9.1 0.0 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat SLT_2 PF13406.1 ETO34713.1 - 0.069 12.0 0.4 0.13 11.1 0.3 1.4 1 0 0 1 1 1 0 Transglycosylase SLT domain RIH_assoc PF08454.6 ETO34713.1 - 2.8 7.5 10.2 9.9 5.8 0.1 4.1 4 2 0 5 5 5 0 RyR and IP3R Homology associated DUF912 PF06024.7 ETO34714.1 - 0.0017 18.4 0.2 0.0034 17.4 0.2 1.5 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3236 PF11576.3 ETO34714.1 - 0.0051 16.2 0.1 0.0088 15.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3236) DUF3753 PF12575.3 ETO34714.1 - 0.0095 15.7 2.4 0.018 14.8 1.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3753) Rifin_STEVOR PF02009.11 ETO34714.1 - 0.018 14.7 0.2 0.024 14.3 0.1 1.3 1 0 0 1 1 1 0 Rifin/stevor family DUF1183 PF06682.7 ETO34714.1 - 0.024 14.2 0.1 0.038 13.6 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) DUF3139 PF11337.3 ETO34714.1 - 0.051 13.8 2.6 0.35 11.1 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Synaptobrevin PF00957.16 ETO34714.1 - 0.64 9.6 5.8 1 9.0 1.4 2.4 2 0 0 2 2 2 0 Synaptobrevin DUF4519 PF15012.1 ETO34714.1 - 1.4 8.8 5.4 0.7 9.8 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) WD40 PF00400.27 ETO34715.1 - 6.7e-30 101.8 3.4 2.9e-09 36.4 0.1 4.1 3 1 1 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO34715.1 - 2.5e-06 25.9 0.2 0.009 14.1 0.0 2.4 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Mid2 PF04478.7 ETO34715.1 - 7.3e-05 22.2 0.6 0.00019 20.8 0.1 1.9 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor DUF3601 PF12208.3 ETO34715.1 - 0.00027 20.7 0.5 0.023 14.6 0.0 3.2 1 1 2 3 3 3 1 Domain of unknown function (DUF3601) DUF1975 PF09318.5 ETO34715.1 - 0.04 13.5 0.2 0.15 11.6 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1975) PD40 PF07676.7 ETO34715.1 - 0.081 12.6 0.4 30 4.4 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat zf-RING_2 PF13639.1 ETO34716.1 - 0.00046 19.9 0.9 0.0015 18.2 0.6 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO34716.1 - 0.00092 19.1 0.9 0.008 16.1 0.6 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-BED PF02892.10 ETO34716.1 - 0.053 13.2 2.5 0.65 9.8 0.1 2.9 2 0 0 2 2 2 0 BED zinc finger DUF1644 PF07800.7 ETO34716.1 - 0.13 12.0 12.3 0.39 10.5 8.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) zf-rbx1 PF12678.2 ETO34716.1 - 0.52 10.4 7.5 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 RING-H2 zinc finger zf-RING-like PF08746.6 ETO34716.1 - 3.3 7.8 7.9 3.5 7.7 3.7 2.5 2 1 1 3 3 3 0 RING-like domain WD40 PF00400.27 ETO34717.1 - 6.3e-11 41.7 3.2 1.1e-10 40.9 2.2 1.4 1 0 0 1 1 1 1 WD domain, G-beta repeat Pox_A21 PF05323.7 ETO34717.1 - 0.039 14.3 0.8 0.071 13.5 0.6 1.5 1 0 0 1 1 1 0 Poxvirus A21 Protein BPL_N PF09825.4 ETO34717.1 - 0.1 11.3 6.6 0.12 11.1 4.6 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal DUF3573 PF12097.3 ETO34717.1 - 2 6.9 16.7 1.3 7.5 10.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) DUF763 PF05559.6 ETO34717.1 - 7.7 5.3 8.3 13 4.6 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF763) TRAM_LAG1_CLN8 PF03798.11 ETO34718.1 - 2.4e-10 40.2 7.7 9.8e-10 38.3 5.4 1.9 1 1 0 1 1 1 1 TLC domain LicD PF04991.8 ETO34719.1 - 6.1 6.9 18.0 0.11 12.6 4.4 3.2 2 2 0 2 2 2 0 LicD family EF-hand_7 PF13499.1 ETO34720.1 - 9.2e-15 54.5 7.6 1.4e-11 44.3 2.5 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 ETO34720.1 - 2.1e-13 48.5 10.4 1.1e-05 24.4 1.1 4.0 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 ETO34720.1 - 9.2e-13 46.9 6.1 2.8e-05 23.6 0.1 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 ETO34720.1 - 1.5e-10 40.5 8.4 5.4e-10 38.7 0.9 3.5 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 ETO34720.1 - 6.6e-10 37.8 4.4 9.4e-05 21.5 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 ETO34720.1 - 4.5e-07 29.6 0.2 1.7e-06 27.8 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain DUF2417 PF10329.4 ETO34720.1 - 0.032 13.6 0.1 0.043 13.2 0.1 1.3 1 0 0 1 1 1 0 Region of unknown function (DUF2417) HAD_2 PF13419.1 ETO34720.1 - 0.12 12.6 0.7 1.2 9.3 0.2 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase YolD PF08863.5 ETO34720.1 - 0.31 10.9 2.0 1.4 8.7 0.1 2.6 2 1 0 2 2 2 0 YolD-like protein 7tm_1 PF00001.16 ETO34721.1 - 0.003 16.7 6.4 0.003 16.7 4.4 1.7 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) IlvGEDA_leader PF08046.6 ETO34721.1 - 0.028 13.5 0.2 0.07 12.2 0.1 1.7 1 0 0 1 1 1 0 IlvGEDA operon leader peptide Git3_C PF11970.3 ETO34721.1 - 0.04 13.6 0.1 1.1 9.0 0.1 2.6 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term Orthoreo_P10 PF07204.6 ETO34721.1 - 0.8 9.4 4.5 7.6 6.3 0.1 2.9 3 1 0 3 3 3 0 Orthoreovirus membrane fusion protein p10 B56 PF01603.15 ETO34722.1 - 2.5e-82 276.6 17.8 2.1e-79 267.0 9.4 3.1 2 1 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) Serglycin PF04360.7 ETO34722.1 - 0.22 11.2 0.7 0.38 10.4 0.5 1.3 1 0 0 1 1 1 0 Serglycin 2OG-FeII_Oxy PF03171.15 ETO34724.1 - 9.2e-05 22.6 0.1 0.00019 21.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 ETO34724.1 - 0.00056 20.4 0.4 0.0012 19.3 0.1 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal RRM_1 PF00076.17 ETO34725.1 - 1.2e-15 56.8 1.4 4.7e-15 54.9 0.1 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO34725.1 - 2.4e-12 46.6 0.0 5.2e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO34725.1 - 7.9e-09 35.2 0.7 2.7e-08 33.5 0.1 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETO34725.1 - 0.035 13.8 0.0 0.075 12.8 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif EcoRI_methylase PF13651.1 ETO34726.1 - 2.6e-06 26.7 5.6 3.3e-06 26.4 3.9 1.0 1 0 0 1 1 1 1 Adenine-specific methyltransferase EcoRI UPF1_Zn_bind PF09416.5 ETO34726.1 - 0.0011 18.5 2.8 0.0014 18.2 2.0 1.2 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) DUF2072 PF09845.4 ETO34726.1 - 0.012 15.5 0.2 0.016 15.1 0.2 1.3 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Rad9 PF04139.8 ETO34726.1 - 0.061 12.4 3.7 0.076 12.1 2.6 1.1 1 0 0 1 1 1 0 Rad9 Rsc14 PF08586.5 ETO34726.1 - 0.35 11.3 2.2 2.2 8.7 0.0 2.1 1 1 1 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit Beta-lactamase PF00144.19 ETO34728.1 - 2e-33 115.8 0.0 2.6e-33 115.4 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 ETO34728.1 - 0.0016 17.7 0.0 0.007 15.6 0.0 1.9 2 0 0 2 2 2 1 D-alanyl-D-alanine carboxypeptidase LRR_6 PF13516.1 ETO34729.1 - 0.017 15.1 2.3 0.023 14.6 0.4 2.2 2 0 0 2 2 2 0 Leucine Rich repeat LRR_4 PF12799.2 ETO34729.1 - 0.026 14.1 0.3 0.053 13.1 0.2 1.5 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) WD40 PF00400.27 ETO34730.1 - 9.6e-20 69.6 7.3 4.9e-11 42.0 0.5 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO34730.1 - 1.9e-05 22.9 0.8 0.0012 17.0 0.1 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 HARP PF07443.8 ETO34730.1 - 0.28 10.5 2.5 3.4 7.1 0.1 2.7 3 0 0 3 3 3 0 HepA-related protein (HARP) WD40 PF00400.27 ETO34731.1 - 6.5e-155 498.1 52.6 4.4e-12 45.3 0.6 16.1 14 2 1 15 15 15 15 WD domain, G-beta repeat NACHT PF05729.7 ETO34731.1 - 5.9e-06 26.0 0.0 1.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Pentapeptide_4 PF13599.1 ETO34731.1 - 3.8e-05 23.4 0.7 0.00015 21.4 0.5 2.0 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETO34731.1 - 4.1e-05 22.7 0.6 8.9e-05 21.6 0.4 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 ETO34731.1 - 0.00065 19.5 0.6 0.0024 17.7 0.4 2.0 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) PD40 PF07676.7 ETO34731.1 - 0.0012 18.4 16.7 10 5.9 0.1 9.2 9 0 0 9 9 9 1 WD40-like Beta Propeller Repeat AAA_18 PF13238.1 ETO34731.1 - 0.012 15.9 0.1 0.012 15.9 0.1 2.7 3 0 0 3 3 3 0 AAA domain Resistin PF06954.6 ETO34731.1 - 0.22 11.8 3.9 65 3.8 0.0 5.3 5 2 2 7 7 7 0 Resistin WD40 PF00400.27 ETO34732.1 - 1.1e-16 60.0 4.4 2.6e-09 36.6 0.1 2.8 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO34732.1 - 0.00032 18.9 0.8 0.072 11.2 0.1 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO34732.1 - 0.00033 20.0 4.0 0.0018 17.6 2.8 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4221) DUF3654 PF12376.3 ETO34732.1 - 0.028 14.2 0.3 0.42 10.4 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3654) Prp19_bind PF06991.6 ETO34733.1 - 2.3e-24 86.1 13.3 2.3e-24 86.1 9.2 5.9 4 1 2 6 6 6 2 Splicing factor, Prp19-binding domain PRP38_assoc PF12871.2 ETO34733.1 - 0.00016 22.1 33.5 0.00016 22.1 23.2 5.5 4 1 1 5 5 5 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Kelch_3 PF13415.1 ETO34734.1 - 2.3e-06 27.5 1.4 0.0018 18.3 0.0 4.3 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO34734.1 - 4.6e-06 26.5 3.0 0.0021 18.1 0.1 3.6 2 1 1 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETO34734.1 - 0.00021 20.9 3.2 2.9 7.7 0.1 5.5 4 1 1 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO34734.1 - 0.00059 19.5 0.1 0.45 10.3 0.0 3.6 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 ETO34734.1 - 0.0012 18.7 1.7 0.09 12.7 0.4 3.5 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 ETO34734.1 - 0.0061 16.0 0.6 0.13 11.8 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Peptidase_C14 PF00656.17 ETO34735.1 - 2.1e-11 44.0 0.6 2.7e-11 43.6 0.4 1.2 1 0 0 1 1 1 1 Caspase domain DnaJ PF00226.26 ETO34736.1 - 4.1e-23 80.8 1.4 6.5e-23 80.2 1.0 1.3 1 0 0 1 1 1 1 DnaJ domain Tubulin PF00091.20 ETO34736.1 - 0.081 12.7 0.2 0.12 12.1 0.1 1.3 1 1 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain Sec62 PF03839.11 ETO34736.1 - 0.53 9.6 3.0 0.64 9.3 2.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DHC_N1 PF08385.7 ETO34737.1 - 1.3e-42 146.0 16.1 1.8e-42 145.4 11.2 1.2 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 Resolvase PF00239.16 ETO34737.1 - 0.015 15.2 1.2 0.015 15.2 0.8 2.8 2 2 2 4 4 4 0 Resolvase, N terminal domain DUF2779 PF11074.3 ETO34737.1 - 0.034 14.1 1.8 0.3 11.1 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function(DUF2779) DUF4206 PF13901.1 ETO34737.1 - 0.27 10.7 6.5 0.095 12.2 1.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4206) WD40 PF00400.27 ETO34738.1 - 5.9e-14 51.3 2.2 2.7e-08 33.3 0.2 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO34738.1 - 0.025 12.7 0.1 0.033 12.3 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO34739.1 - 2.9e-06 27.5 0.8 2.9e-06 27.5 0.6 2.6 2 0 0 2 2 2 1 TRAF-type zinc finger Nodulin_late PF07127.6 ETO34740.1 - 0.3 11.2 3.3 0.36 10.9 0.1 2.3 2 0 0 2 2 2 0 Late nodulin protein PUB PF09409.5 ETO34741.1 - 0.00037 20.1 1.7 0.0074 16.0 1.2 2.6 1 1 0 1 1 1 1 PUB domain 14-3-3 PF00244.15 ETO34742.1 - 0.045 12.8 4.1 0.06 12.4 2.9 1.1 1 0 0 1 1 1 0 14-3-3 protein Rad54_N PF08658.5 ETO34742.1 - 0.094 12.4 3.4 0.13 11.9 2.3 1.1 1 0 0 1 1 1 0 Rad54 N terminal PWI PF01480.12 ETO34743.1 - 0.16 12.0 0.4 0.45 10.6 0.1 1.8 2 0 0 2 2 2 0 PWI domain ICMT PF04140.9 ETO34743.1 - 0.33 11.1 8.3 0.13 12.5 3.0 2.0 1 1 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF778 PF05608.7 ETO34744.1 - 0.25 11.2 4.0 13 5.6 2.8 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF778) Prp18 PF02840.10 ETO34744.1 - 0.29 10.9 4.3 6.5 6.5 1.5 2.2 2 0 0 2 2 2 0 Prp18 domain RXT2_N PF08595.6 ETO34744.1 - 1.1 9.1 10.3 0.5 10.1 5.6 1.6 1 1 0 1 1 1 0 RXT2-like, N-terminal DUF506 PF04720.7 ETO34744.1 - 2.1 7.9 8.2 0.47 10.0 3.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF506) SRI PF08236.6 ETO34744.1 - 2.2 8.3 7.9 5.6 6.9 5.1 2.1 1 1 1 2 2 2 0 SRI (Set2 Rpb1 interacting) domain WD40 PF00400.27 ETO34745.1 - 5.4e-62 203.6 20.1 1.2e-11 44.0 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO34745.1 - 1.7e-12 46.2 2.9 0.04 12.0 0.0 5.5 2 2 2 5 5 5 4 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO34745.1 - 7e-05 22.5 3.3 0.98 9.2 0.2 4.3 3 2 0 3 3 3 3 Ciliary BBSome complex subunit 2, middle region DUF4024 PF13216.1 ETO34745.1 - 0.014 15.1 0.4 2 8.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4024) SBP56 PF05694.6 ETO34745.1 - 0.026 13.0 0.1 1.4 7.2 0.1 2.3 2 0 0 2 2 2 0 56kDa selenium binding protein (SBP56) Nucleoporin_N PF08801.6 ETO34745.1 - 0.028 13.1 11.2 0.4 9.3 1.3 4.2 1 1 3 4 4 4 0 Nup133 N terminal like DUF2559 PF10832.3 ETO34745.1 - 3.7 7.4 4.6 2.3 8.0 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2559) HEAT PF02985.17 ETO34746.1 - 8.4e-30 100.1 8.8 0.0041 17.0 0.0 9.4 9 0 0 9 9 9 8 HEAT repeat HEAT_2 PF13646.1 ETO34746.1 - 4.6e-21 74.9 3.3 2.6e-07 30.8 0.1 5.7 2 1 4 6 6 6 5 HEAT repeats Vac14_Fab1_bd PF12755.2 ETO34746.1 - 7.3e-08 32.7 0.0 0.29 11.5 0.0 4.4 2 1 2 4 4 4 3 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 ETO34746.1 - 1.2e-05 24.8 1.6 1.3 8.2 0.1 5.2 2 2 3 5 5 5 2 CLASP N terminal HEAT_EZ PF13513.1 ETO34746.1 - 2e-05 24.8 1.5 0.26 11.8 0.0 5.6 5 1 1 6 6 6 1 HEAT-like repeat Adaptin_N PF01602.15 ETO34746.1 - 0.00037 18.9 3.3 0.13 10.6 0.1 3.6 1 1 0 2 2 2 2 Adaptin N terminal region Cohesin_HEAT PF12765.2 ETO34746.1 - 0.00067 19.5 1.9 0.15 12.0 0.0 4.4 5 0 0 5 5 5 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 ETO34746.1 - 0.0033 17.2 0.6 0.38 10.5 0.0 4.0 4 2 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 DUF4042 PF13251.1 ETO34746.1 - 0.039 13.4 0.1 13 5.2 0.0 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4042) Cytadhesin_P30 PF07271.6 ETO34747.1 - 0.083 12.1 3.6 0.14 11.4 1.9 1.8 1 1 0 1 1 1 0 Cytadhesin P30/P32 Nucleo_P87 PF07267.6 ETO34747.1 - 8 5.0 15.5 10 4.6 10.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Neur_chan_memb PF02932.11 ETO34747.1 - 8.8 6.1 8.8 0.73 9.6 2.5 1.8 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region WD40 PF00400.27 ETO34748.1 - 6.1e-61 200.2 18.3 4.9e-11 42.0 0.3 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO34748.1 - 1.1e-17 63.4 2.4 0.014 13.5 0.0 6.3 1 1 5 6 6 6 6 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO34748.1 - 6e-07 29.7 1.0 6e-07 29.7 0.7 2.5 2 1 0 2 2 2 1 TRAF-type zinc finger Phage_GPO PF05929.6 ETO34748.1 - 0.74 9.0 9.9 1.3 8.2 6.9 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase TPR_11 PF13414.1 ETO34750.1 - 3.6e-06 26.5 0.9 3e-05 23.5 0.6 2.2 1 1 0 1 1 1 1 TPR repeat TPR_12 PF13424.1 ETO34750.1 - 0.0019 18.0 0.1 0.19 11.6 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO34750.1 - 0.006 16.4 0.9 0.03 14.2 0.4 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat DASH_Dam1 PF08653.5 ETO34750.1 - 0.012 15.3 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 DASH complex subunit Dam1 BAR PF03114.13 ETO34750.1 - 0.015 14.7 0.7 0.033 13.6 0.5 1.5 1 0 0 1 1 1 0 BAR domain MIT PF04212.13 ETO34750.1 - 0.067 13.0 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.23 ETO34750.1 - 0.13 11.9 0.8 0.72 9.5 0.4 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 ETO34750.1 - 0.28 11.3 2.9 1.7 8.8 0.5 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 F-box PF00646.28 ETO34752.1 - 7e-06 25.5 1.7 7e-06 25.5 1.2 1.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 ETO34752.1 - 5.4e-05 22.8 2.6 0.00011 21.8 1.8 1.5 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 ETO34752.1 - 0.003 17.4 0.3 3.8 7.8 0.0 3.2 3 0 0 3 3 3 1 Leucine Rich repeat LRR_4 PF12799.2 ETO34752.1 - 0.01 15.4 0.0 0.028 14.0 0.0 1.7 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) Bd3614_N PF14442.1 ETO34752.1 - 0.061 13.3 1.7 0.092 12.7 1.2 1.2 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal LRR_1 PF00560.28 ETO34752.1 - 0.19 11.8 1.2 3 8.2 0.0 3.3 4 0 0 4 4 4 0 Leucine Rich Repeat Sigma70_ner PF04546.8 ETO34752.1 - 0.76 9.3 4.8 0.53 9.8 1.5 2.0 3 0 0 3 3 3 0 Sigma-70, non-essential region Tom22 PF04281.8 ETO34752.1 - 2.2 7.7 7.0 3.7 7.0 4.9 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 HARP PF07443.8 ETO34754.1 - 0.088 12.1 0.4 0.2 11.0 0.0 1.8 2 0 0 2 2 2 0 HepA-related protein (HARP) DUF92 PF01940.11 ETO34755.1 - 1e-36 126.2 8.7 2.5e-28 98.7 1.2 2.2 2 0 0 2 2 2 2 Integral membrane protein DUF92 Oleosin PF01277.12 ETO34755.1 - 0.12 11.9 1.0 0.26 10.8 0.7 1.5 1 0 0 1 1 1 0 Oleosin DUF3671 PF12420.3 ETO34756.1 - 0.065 13.2 0.4 0.12 12.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function Lectin_N PF03954.9 ETO34756.1 - 1 8.7 5.4 8 5.8 3.7 1.9 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain Methyltransf_21 PF05050.7 ETO34757.1 - 4.6e-09 36.4 0.2 1.3e-08 34.9 0.1 1.8 2 1 0 2 2 2 1 Methyltransferase FkbM domain CHORD PF04968.7 ETO34757.1 - 0.0093 16.1 0.5 0.022 14.9 0.3 1.6 1 0 0 1 1 1 1 CHORD ELH PF02323.10 ETO34758.1 - 0.006 15.7 4.0 0.011 14.9 2.8 1.4 1 0 0 1 1 1 1 Egg-laying hormone precursor PWWP PF00855.12 ETO34759.1 - 1.1e-05 25.5 5.4 0.0047 17.1 0.1 3.6 3 1 0 3 3 3 2 PWWP domain DUF726 PF05277.7 ETO34759.1 - 0.076 11.8 0.1 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Phospholip_B PF04916.8 ETO34760.1 - 1.9e-08 32.8 2.2 3.4e-08 32.0 1.5 1.3 1 1 0 1 1 1 1 Phospholipase B XH PF03469.9 ETO34760.1 - 0.031 13.9 0.0 0.047 13.3 0.0 1.2 1 0 0 1 1 1 0 XH domain NAD_kinase PF01513.16 ETO34761.1 - 1.8e-36 125.3 0.2 2.6e-35 121.6 0.1 2.0 2 0 0 2 2 2 2 ATP-NAD kinase WD40 PF00400.27 ETO34762.1 - 5.1e-43 143.4 11.9 1.5e-08 34.2 0.3 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO34762.1 - 6.6e-06 24.5 3.5 0.025 12.7 0.0 2.9 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Ricin_B_lectin PF00652.17 ETO34762.1 - 7.3 6.6 8.1 4.3 7.4 1.6 2.5 2 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain PBP1_TM PF14812.1 ETO34763.1 - 0.76 10.1 11.9 2.8 8.3 0.2 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PPR_2 PF13041.1 ETO34765.1 - 0.013 15.4 0.0 0.055 13.4 0.0 2.1 1 0 0 1 1 1 0 PPR repeat family YfiO PF13525.1 ETO34765.1 - 0.021 14.3 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 Outer membrane lipoprotein DUF1311 PF07007.7 ETO34765.1 - 0.033 14.2 0.0 0.16 12.0 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1311) Dus PF01207.12 ETO34766.1 - 2.2e-33 115.4 0.1 2.6e-33 115.2 0.1 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) YcgL PF05166.8 ETO34766.1 - 0.037 14.1 0.3 4.8 7.3 0.0 2.6 2 1 1 3 3 3 0 YcgL domain His_biosynth PF00977.16 ETO34766.1 - 0.059 12.6 0.0 0.12 11.5 0.0 1.7 1 1 0 1 1 1 0 Histidine biosynthesis protein Dus PF01207.12 ETO34767.1 - 3.7e-15 55.5 0.0 5.5e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Ank_4 PF13637.1 ETO34769.1 - 0.00067 20.0 0.0 0.032 14.7 0.0 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO34769.1 - 0.0011 18.9 0.0 0.54 10.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 ETO34769.1 - 0.0048 17.1 0.1 0.15 12.4 0.1 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO34769.1 - 0.023 14.4 0.0 0.1 12.4 0.0 2.1 1 1 0 1 1 1 0 Ankyrin repeat CAP_GLY PF01302.20 ETO34771.1 - 3.7e-12 45.7 1.9 8.4e-08 31.8 0.4 2.5 2 0 0 2 2 2 2 CAP-Gly domain S-AdoMet_synt_M PF02772.11 ETO34771.1 - 1.7 8.6 4.4 0.6 10.0 1.0 1.8 2 0 0 2 2 2 0 S-adenosylmethionine synthetase, central domain WD40 PF00400.27 ETO34772.1 - 2.7e-13 49.2 6.0 4.1e-11 42.3 0.9 2.9 2 1 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO34772.1 - 0.017 13.2 0.0 0.019 13.1 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Serpin PF00079.15 ETO34773.1 - 1.9e-25 89.7 4.9 2.3e-25 89.5 3.4 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) PDZ PF00595.19 ETO34774.1 - 0.032 14.4 0.0 0.077 13.1 0.0 1.6 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) Caps_synth_CapC PF14102.1 ETO34774.1 - 0.044 13.9 1.4 0.22 11.6 0.1 2.3 2 0 0 2 2 2 0 Capsule biosynthesis CapC DUF3089 PF11288.3 ETO34775.1 - 3.2e-10 39.5 0.0 4.1e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) DUF3089 PF11288.3 ETO34776.1 - 1.6e-18 66.5 0.1 3.2e-18 65.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3089) HalX PF08663.5 ETO34777.1 - 0.043 13.8 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 HalX domain F-protein PF00469.15 ETO34777.1 - 2.9 7.1 10.3 2.1e+02 1.1 7.1 2.1 1 1 0 1 1 1 0 Negative factor, (F-Protein) or Nef GPS PF01825.16 ETO34779.1 - 0.0032 17.5 10.5 0.005 16.9 5.9 2.4 2 0 0 2 2 2 1 Latrophilin/CL-1-like GPS domain DUF3357 PF11837.3 ETO34779.1 - 0.15 11.9 1.4 0.64 9.8 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) DUF1387 PF07139.6 ETO34780.1 - 0.22 11.1 17.4 0.26 10.8 12.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) MIP-T3 PF10243.4 ETO34780.1 - 9.4 4.5 29.3 10 4.4 20.3 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Herpes_env PF01673.13 ETO34781.1 - 0.32 9.4 4.4 0.35 9.3 3.0 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Anoctamin PF04547.7 ETO34782.1 - 0.076 11.6 0.2 0.07 11.7 0.1 1.0 1 0 0 1 1 1 0 Calcium-activated chloride channel BAH PF01426.13 ETO34782.1 - 0.094 12.4 0.2 0.13 12.0 0.2 1.4 1 1 0 1 1 1 0 BAH domain Wound_ind PF08186.6 ETO34785.1 - 0.0048 16.7 1.2 0.016 15.1 0.4 2.2 2 0 0 2 2 2 1 Wound-inducible basic protein family DARPP-32 PF05395.7 ETO34785.1 - 0.36 10.9 10.8 2.5 8.2 2.5 2.3 2 0 0 2 2 2 0 Protein phosphatase inhibitor 1/DARPP-32 YlqD PF11068.3 ETO34786.1 - 0.00042 20.3 6.9 0.00063 19.7 4.8 1.3 1 0 0 1 1 1 1 YlqD protein DUF4631 PF15450.1 ETO34786.1 - 0.002 16.4 7.5 0.0026 16.1 5.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4631) DUF342 PF03961.8 ETO34786.1 - 0.0094 14.4 5.3 0.011 14.1 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF342) RTX_C PF08339.5 ETO34786.1 - 0.011 15.3 3.4 0.018 14.7 2.3 1.3 1 0 0 1 1 1 0 RTX C-terminal domain FMO-like PF00743.14 ETO34786.1 - 0.014 13.5 0.0 0.022 13.0 0.0 1.3 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Snf7 PF03357.16 ETO34786.1 - 0.015 14.7 7.9 0.022 14.1 5.5 1.2 1 0 0 1 1 1 0 Snf7 V-set_CD47 PF08204.6 ETO34786.1 - 0.031 14.0 2.3 0.22 11.3 1.6 2.1 1 1 0 1 1 1 0 CD47 immunoglobulin-like domain Peptidase_S64 PF08192.6 ETO34786.1 - 0.049 11.9 3.2 0.067 11.5 2.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 APG6 PF04111.7 ETO34786.1 - 0.22 10.5 9.8 0.3 10.1 6.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2968 PF11180.3 ETO34786.1 - 0.49 9.7 6.1 0.75 9.1 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) IPK PF03770.11 ETO34786.1 - 0.56 9.8 8.6 0.53 9.8 1.3 2.1 1 1 1 2 2 2 0 Inositol polyphosphate kinase IncA PF04156.9 ETO34786.1 - 1.3 8.5 14.4 0.018 14.6 5.0 1.5 2 0 0 2 2 2 0 IncA protein Viral_P18 PF04521.8 ETO34786.1 - 3 7.2 6.5 2.6 7.4 2.9 2.0 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein cNMP_binding PF00027.24 ETO34788.1 - 2.9e-37 126.3 0.1 1.5e-19 69.6 0.1 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase PF00069.20 ETO34788.1 - 5.8e-28 97.7 0.0 1.8e-27 96.1 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO34788.1 - 2.2e-08 33.4 0.0 4.4e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Cupin_2 PF07883.6 ETO34788.1 - 0.26 10.8 0.9 0.88 9.1 0.2 2.0 2 0 0 2 2 2 0 Cupin domain Pkinase PF00069.20 ETO34789.1 - 1.6e-19 70.1 0.0 2e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO34789.1 - 2.6e-06 26.6 0.0 3.6e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO34789.1 - 0.0056 15.6 0.0 0.0071 15.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kelch_6 PF13964.1 ETO34790.1 - 2.8e-07 30.4 5.7 0.018 15.1 0.3 4.6 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO34790.1 - 1.6e-05 24.3 4.5 0.0001 21.7 0.5 3.6 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 ETO34790.1 - 0.00018 21.1 5.0 0.016 14.9 0.2 4.5 4 1 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO34790.1 - 0.00095 18.8 0.0 0.84 9.4 0.0 2.9 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO34790.1 - 0.0027 17.8 0.0 0.087 13.0 0.0 3.4 4 0 0 4 4 4 1 Galactose oxidase, central domain WD40 PF00400.27 ETO34791.1 - 2.5e-61 201.5 8.4 6.5e-11 41.6 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO34791.1 - 9.6e-08 31.9 0.0 9e-05 22.2 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A DUF1258 PF06869.7 ETO34791.1 - 5.1e-06 25.7 0.7 0.015 14.3 0.1 3.4 2 2 2 4 4 4 2 Protein of unknown function (DUF1258) Nbas_N PF15492.1 ETO34791.1 - 5e-05 22.5 0.2 0.26 10.3 0.0 3.1 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 ETO34791.1 - 0.00064 19.3 9.3 8 6.2 0.0 4.9 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO34791.1 - 0.001 17.2 1.2 10 4.0 0.0 4.1 1 1 4 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO34791.1 - 0.0024 16.7 5.6 4.9 5.7 0.0 4.3 1 1 3 4 4 4 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO34791.1 - 0.011 14.0 0.2 3.9 5.6 0.0 2.8 3 0 0 3 3 3 0 Cytochrome D1 heme domain Resistin PF06954.6 ETO34791.1 - 0.04 14.1 0.1 31 4.9 0.0 4.1 4 1 2 6 6 6 0 Resistin BBS2_Mid PF14783.1 ETO34791.1 - 0.066 13.0 1.4 23 4.8 0.1 3.9 1 1 3 4 4 4 0 Ciliary BBSome complex subunit 2, middle region DDHD PF02862.12 ETO34792.1 - 3.4 7.3 13.2 0.6 9.8 3.1 2.2 2 0 0 2 2 2 0 DDHD domain DUF61 PF01886.11 ETO34793.1 - 0.043 13.6 2.1 0.059 13.2 0.3 2.1 2 1 0 2 2 2 0 Protein of unknown function DUF61 RR_TM4-6 PF06459.7 ETO34794.1 - 2.4 7.9 11.2 3.3 7.5 7.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 UbiD PF01977.11 ETO34795.1 - 0.11 10.9 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase PRP1_N PF06424.7 ETO34796.1 - 0.12 12.6 3.5 3.7 7.8 0.8 2.5 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Receptor_2B4 PF11465.3 ETO34796.1 - 0.97 9.3 4.4 0.61 10.0 0.2 2.5 3 0 0 3 3 3 0 Natural killer cell receptor 2B4 Kelch_6 PF13964.1 ETO34797.1 - 1.7e-07 31.1 2.3 0.032 14.4 0.1 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO34797.1 - 9.8e-07 28.2 2.0 0.0051 16.3 0.1 4.5 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 ETO34797.1 - 2.4e-06 27.1 4.0 0.011 15.4 0.1 4.4 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO34797.1 - 2.9e-06 26.9 0.1 0.014 15.1 0.0 4.1 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO34797.1 - 0.0025 17.9 0.4 0.026 14.6 0.0 2.9 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO34797.1 - 0.0037 17.1 7.6 0.56 10.2 0.2 4.6 5 0 0 5 5 5 1 Kelch motif PI3K_C2 PF00792.19 ETO34801.1 - 4.5e-08 32.9 0.1 0.00061 19.5 0.0 2.9 2 0 0 2 2 2 2 Phosphoinositide 3-kinase C2 IL4Ra_N PF09238.5 ETO34801.1 - 0.028 14.4 0.2 0.085 12.9 0.1 1.8 1 0 0 1 1 1 0 Interleukin-4 receptor alpha chain, N-terminal PolyA_pol_arg_C PF12626.2 ETO34801.1 - 0.096 12.3 4.6 0.3 10.7 0.0 3.0 2 0 0 2 2 2 0 Polymerase A arginine-rich C-terminus RasGEF PF00617.14 ETO34802.1 - 6.8e-24 84.6 0.7 7.2e-18 64.9 0.3 2.3 2 0 0 2 2 2 2 RasGEF domain WD40 PF00400.27 ETO34803.1 - 4.9e-75 244.9 20.1 2.7e-13 49.2 0.0 8.7 9 0 0 9 9 9 7 WD domain, G-beta repeat PD40 PF07676.7 ETO34803.1 - 7.6e-15 54.1 11.4 0.043 13.4 0.0 6.9 7 0 0 7 7 7 6 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO34803.1 - 1.7e-05 23.1 6.7 0.59 8.2 0.1 5.3 2 2 1 4 4 4 3 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 ETO34803.1 - 2.3e-05 23.3 0.1 0.00022 20.1 0.0 2.2 1 1 1 2 2 2 1 Coatomer WD associated region Nucleoporin_N PF08801.6 ETO34803.1 - 3.8e-05 22.6 15.2 0.015 14.0 0.3 5.3 2 2 4 6 6 6 2 Nup133 N terminal like Nbas_N PF15492.1 ETO34803.1 - 8.2e-05 21.8 3.0 1.5 7.9 0.0 4.2 2 1 3 5 5 5 2 Neuroblastoma-amplified sequence, N terminal DPPIV_N PF00930.16 ETO34803.1 - 0.0002 20.0 0.0 4.1 5.8 0.0 5.0 2 1 1 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Mid2 PF04478.7 ETO34803.1 - 0.0014 18.0 2.5 1.9 7.9 0.1 3.5 2 2 1 3 3 3 2 Mid2 like cell wall stress sensor PQQ_2 PF13360.1 ETO34803.1 - 0.0016 17.9 0.1 0.081 12.3 0.0 3.0 1 1 1 2 2 2 2 PQQ-like domain Pectate_lyase22 PF14583.1 ETO34803.1 - 0.0038 15.7 0.0 0.89 7.9 0.0 2.6 2 0 0 2 2 2 2 Oligogalacturonate lyase POLO_box PF00659.13 ETO34803.1 - 0.011 15.7 0.5 26 4.8 0.0 5.2 4 2 1 5 5 5 0 POLO box duplicated region Str_synth PF03088.11 ETO34803.1 - 0.012 15.6 0.1 5 7.2 0.0 3.5 3 1 0 3 3 3 0 Strictosidine synthase Cytochrom_D1 PF02239.11 ETO34803.1 - 0.28 9.4 1.7 1.1 7.5 0.0 2.6 3 1 1 4 4 4 0 Cytochrome D1 heme domain DivIC PF04977.10 ETO34804.1 - 0.21 11.0 2.5 1.5 8.3 1.4 2.3 2 0 0 2 2 2 0 Septum formation initiator Cauli_AT PF03233.8 ETO34804.1 - 0.34 10.6 5.3 0.48 10.1 3.7 1.2 1 0 0 1 1 1 0 Aphid transmission protein Pkinase PF00069.20 ETO34807.1 - 1.4e-28 99.7 3.8 2.7e-15 56.2 0.1 2.3 1 1 1 2 2 2 2 Protein kinase domain cNMP_binding PF00027.24 ETO34807.1 - 8e-19 67.2 0.2 2.6e-18 65.5 0.0 2.0 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.12 ETO34807.1 - 1e-11 44.4 1.4 3.7e-07 29.4 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Glyco_hydro_88 PF07470.8 ETO34807.1 - 0.028 13.4 0.3 0.028 13.4 0.2 1.7 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 cNMP_binding PF00027.24 ETO34808.1 - 1e-39 134.2 0.5 3.2e-23 81.3 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.6 ETO34808.1 - 0.0024 17.3 0.4 0.015 14.7 0.0 2.2 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.7 ETO34808.1 - 0.077 12.3 0.3 0.26 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF861) WD40 PF00400.27 ETO34809.1 - 2.4e-16 58.9 2.3 1.1e-10 41.0 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO34809.1 - 0.00056 18.1 1.5 0.036 12.1 0.0 2.4 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO34809.1 - 0.005 15.6 1.6 0.0094 14.7 1.1 1.4 1 0 0 1 1 1 1 Nup133 N terminal like PQQ_2 PF13360.1 ETO34809.1 - 0.014 14.8 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 PQQ-like domain CNH PF00780.17 ETO34809.1 - 0.021 14.2 0.6 6.6 6.0 0.0 2.8 3 0 0 3 3 3 0 CNH domain Qn_am_d_aII PF14930.1 ETO34809.1 - 0.06 13.3 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II IBV_3A PF03617.8 ETO34809.1 - 0.072 12.8 1.7 0.27 11.0 1.2 2.0 1 0 0 1 1 1 0 IBV 3A protein DUF3753 PF12575.3 ETO34810.1 - 0.024 14.4 2.1 0.049 13.4 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) SIS PF01380.17 ETO34810.1 - 0.062 12.9 1.5 0.21 11.2 0.2 2.0 2 0 0 2 2 2 0 SIS domain Viral_Beta_CD PF04530.7 ETO34810.1 - 0.11 12.7 0.2 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Viral Beta C/D like family DEC-1_N PF04625.8 ETO34810.1 - 1.1 7.8 7.7 2.1 6.9 5.4 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Vac14_Fab1_bd PF12755.2 ETO34811.1 - 0.29 11.5 0.0 0.29 11.5 0.0 3.3 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Aa_trans PF01490.13 ETO34813.1 - 5.1e-47 160.2 20.3 3.9e-46 157.3 14.1 1.9 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3593 PF12159.3 ETO34813.1 - 0.31 10.8 6.6 0.2 11.4 0.4 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3593) COX7C PF02935.11 ETO34813.1 - 6 6.7 8.3 5.5 6.8 2.1 2.9 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIIc MORN PF02493.15 ETO34814.1 - 1.2e-25 87.6 27.2 6.8e-09 34.9 1.1 6.7 7 0 0 7 7 7 5 MORN repeat DUF2242 PF10001.4 ETO34815.1 - 0.053 13.3 0.8 0.098 12.5 0.5 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2242) Kei1 PF08552.6 ETO34815.1 - 0.088 12.4 6.8 0.013 15.1 1.3 1.8 1 1 1 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Peptidase_S49_N PF08496.5 ETO34815.1 - 3.2 7.5 9.9 0.27 11.0 2.7 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal RTC PF01137.16 ETO34817.1 - 2.6e-26 91.8 0.0 3.3e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Complex1_LYR PF05347.10 ETO34818.1 - 8.3e-09 35.1 4.9 2.5e-08 33.5 3.4 1.9 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 ETO34818.1 - 7.1e-07 29.3 5.8 1.4e-06 28.4 4.0 1.5 1 0 0 1 1 1 1 Complex1_LYR-like DUF1891 PF09004.5 ETO34818.1 - 0.00052 19.3 0.1 0.0011 18.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1891) Complex1_LYR_2 PF13233.1 ETO34818.1 - 1.2 9.6 5.1 2.1 8.8 3.0 1.8 1 1 0 1 1 1 0 Complex1_LYR-like Pkinase PF00069.20 ETO34819.1 - 6.5e-43 146.7 0.5 6.5e-43 146.7 0.3 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO34819.1 - 1.8e-14 53.4 0.0 3.5e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETO34819.1 - 5.6e-05 22.9 0.0 0.1 12.3 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 ETO34819.1 - 0.007 15.4 0.2 0.014 14.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Plasmodium_Vir PF05795.6 ETO34819.1 - 0.035 13.3 1.2 0.051 12.7 0.7 1.4 1 1 0 1 1 1 0 Plasmodium vivax Vir protein YrbL-PhoP_reg PF10707.4 ETO34819.1 - 0.047 13.0 0.3 0.14 11.5 0.1 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kinase-like PF14531.1 ETO34819.1 - 0.072 12.0 1.0 8.5 5.2 0.0 2.7 2 1 0 2 2 2 0 Kinase-like RNA_pol_Rpb5_C PF01191.14 ETO34819.1 - 0.084 12.4 0.2 0.19 11.3 0.1 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain C6_DPF PF10170.4 ETO34820.1 - 0.052 13.6 0.6 0.11 12.5 0.4 1.6 2 0 0 2 2 2 0 Cysteine-rich domain Voltage_CLC PF00654.15 ETO34822.1 - 1.1e-32 113.4 8.9 1.3e-32 113.1 6.2 1.0 1 0 0 1 1 1 1 Voltage gated chloride channel Gly-zipper_YMGG PF13441.1 ETO34822.1 - 1.9 8.0 7.9 0.79 9.2 3.7 1.6 2 0 0 2 2 2 0 YMGG-like Gly-zipper DUF3037 PF11236.3 ETO34823.1 - 0.063 13.3 0.1 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) DUF3216 PF11505.3 ETO34823.1 - 0.077 12.8 0.3 0.14 11.9 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3216) MIP-T3 PF10243.4 ETO34824.1 - 2.4e-12 46.1 16.8 3.5e-12 45.5 0.0 2.0 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 Vfa1 PF08432.5 ETO34824.1 - 0.0056 16.7 6.2 0.0081 16.1 4.3 1.2 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Mem_trans PF03547.13 ETO34824.1 - 0.97 7.6 4.4 1.4 7.1 3.0 1.4 1 1 0 1 1 1 0 Membrane transport protein Tom5 PF10642.4 ETO34824.1 - 0.97 9.1 0.0 0.97 9.1 0.0 3.0 4 0 0 4 4 4 0 Mitochondrial import receptor subunit or translocase Tim54 PF11711.3 ETO34824.1 - 3.5 6.1 10.1 5.2 5.5 7.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 MIP-T3 PF10243.4 ETO34825.1 - 2.5e-17 62.5 15.2 3.1e-17 62.2 10.5 1.0 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 AAA_23 PF13476.1 ETO34825.1 - 0.23 11.7 13.4 0.35 11.1 9.3 1.2 1 0 0 1 1 1 0 AAA domain LAGLIDADG_WhiA PF14527.1 ETO34825.1 - 0.41 10.5 3.9 0.25 11.2 1.1 1.9 2 0 0 2 2 2 0 WhiA LAGLIDADG-like domain AAA_11 PF13086.1 ETO34825.1 - 0.49 9.9 5.4 0.68 9.4 3.8 1.2 1 0 0 1 1 1 0 AAA domain TPR_12 PF13424.1 ETO34827.1 - 2.9e-20 71.9 0.4 1e-09 38.1 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO34827.1 - 7.7e-11 41.4 3.1 4.7e-07 29.3 1.4 2.6 1 1 1 2 2 2 2 TPR repeat TPR_7 PF13176.1 ETO34827.1 - 1.6e-09 36.8 1.7 0.0012 18.4 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO34827.1 - 3.7e-09 35.7 10.2 1.5e-06 27.5 1.9 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO34827.1 - 5.3e-09 35.3 7.6 1.6e-05 24.4 0.8 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO34827.1 - 8.2e-09 35.1 0.0 0.00056 19.7 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO34827.1 - 1.1e-06 27.9 9.7 0.00016 21.2 2.4 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO34827.1 - 0.0073 16.8 0.0 0.19 12.4 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 ETO34827.1 - 0.013 15.3 0.5 0.058 13.2 0.4 2.1 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Peptidase_C14 PF00656.17 ETO34827.1 - 0.016 14.9 1.8 0.12 11.9 0.0 3.1 4 0 0 4 4 4 0 Caspase domain TPR_6 PF13174.1 ETO34827.1 - 0.019 15.3 2.8 1.3 9.6 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat ParG PF09274.5 ETO34827.1 - 0.059 13.2 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 ParG TPR_16 PF13432.1 ETO34827.1 - 0.14 12.8 0.0 6.3 7.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.20 ETO34828.1 - 5.8e-36 123.9 0.8 7.4e-36 123.6 0.5 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO34828.1 - 1.5e-24 86.5 0.1 2e-24 86.0 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO34828.1 - 0.00025 20.1 0.0 0.00041 19.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETO34828.1 - 0.00029 20.6 1.4 0.0011 18.7 0.9 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 ETO34828.1 - 0.00062 19.1 0.1 0.001 18.4 0.1 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 ETO34828.1 - 0.0097 15.2 0.3 0.014 14.7 0.2 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 ETO34828.1 - 0.058 12.9 0.4 0.084 12.4 0.3 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1325 PF07039.6 ETO34828.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.5 1 1 0 1 1 1 0 SGF29 tudor-like domain Kelch_6 PF13964.1 ETO34829.1 - 1.4e-08 34.5 3.9 0.0026 17.8 0.2 5.0 4 1 1 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO34829.1 - 5.9e-06 25.8 1.8 0.025 14.3 0.1 4.2 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO34829.1 - 4.3e-05 23.2 0.1 0.00079 19.1 0.0 2.8 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO34829.1 - 7.4e-05 22.2 5.7 0.0012 18.3 1.7 3.8 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 ETO34829.1 - 0.00021 21.3 0.0 0.0026 17.8 0.0 2.9 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO34829.1 - 0.0015 18.3 0.3 8.7 6.4 0.6 4.2 4 0 0 4 4 4 1 Kelch motif DUF4084 PF13321.1 ETO34829.1 - 0.0025 17.0 1.6 0.004 16.4 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4084) WD40 PF00400.27 ETO34830.1 - 5.7e-41 136.9 22.0 1.1e-07 31.3 0.5 8.1 9 0 0 9 9 9 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO34830.1 - 3.7e-08 31.9 4.3 0.0037 15.4 0.0 4.4 2 1 1 3 3 3 3 Nucleoporin Nup120/160 WD40 PF00400.27 ETO34832.1 - 1.8e-28 97.3 9.3 9.3e-12 44.3 0.1 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO34832.1 - 3.6e-06 25.4 1.1 0.061 11.4 0.0 2.9 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF1581 PF07619.6 ETO34833.1 - 0.012 15.6 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1581) RNA_pol_Rpb5_C PF01191.14 ETO34835.1 - 0.13 11.9 0.1 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain Clc-like PF07062.7 ETO34836.1 - 0.074 12.2 1.4 0.1 11.8 1.0 1.2 1 0 0 1 1 1 0 Clc-like WD40 PF00400.27 ETO34837.1 - 3.1e-10 39.5 0.3 3e-09 36.3 0.0 2.5 3 0 0 3 3 3 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO34837.1 - 0.087 10.9 0.2 0.26 9.3 0.0 1.6 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Peptidase_S49_N PF08496.5 ETO34838.1 - 2.3 7.9 6.4 0.36 10.6 1.6 1.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal RRS1 PF04939.7 ETO34838.1 - 4.7 6.6 11.6 1.8 7.9 5.3 2.0 2 0 0 2 2 2 0 Ribosome biogenesis regulatory protein (RRS1) DUF3671 PF12420.3 ETO34838.1 - 6.1 6.8 11.7 0.83 9.6 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function Lipocalin PF00061.18 ETO34839.1 - 0.093 12.7 0.0 0.2 11.6 0.0 1.5 2 0 0 2 2 2 0 Lipocalin / cytosolic fatty-acid binding protein family UCH PF00443.24 ETO34840.1 - 2.3e-30 105.6 0.0 2.5e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO34840.1 - 0.0067 15.9 0.0 0.0082 15.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_S27e PF01667.12 ETO34840.1 - 0.015 14.8 0.1 0.61 9.6 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein S27 PPR_2 PF13041.1 ETO34841.1 - 4.2e-09 36.2 0.1 7.7e-07 28.9 0.1 2.7 2 0 0 2 2 2 1 PPR repeat family PPR PF01535.15 ETO34841.1 - 3.3e-05 23.5 0.9 0.0016 18.3 0.1 3.4 3 0 0 3 3 3 1 PPR repeat PPR_1 PF12854.2 ETO34841.1 - 0.001 18.5 0.0 0.0027 17.1 0.0 1.7 1 0 0 1 1 1 1 PPR repeat PPR_3 PF13812.1 ETO34841.1 - 0.0033 17.5 0.0 6.8 7.2 0.0 3.4 3 0 0 3 3 3 2 Pentatricopeptide repeat domain ATP13 PF12921.2 ETO34841.1 - 0.03 13.6 4.2 0.092 12.1 0.0 3.3 3 1 1 4 4 4 0 Mitochondrial ATPase expression AAA_6 PF12774.2 ETO34841.1 - 0.076 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region D1 Ras PF00071.17 ETO34843.1 - 9.1e-36 122.6 0.7 2.2e-25 88.9 0.3 2.2 2 0 0 2 2 2 2 Ras family Miro PF08477.8 ETO34843.1 - 2.4e-17 63.5 0.5 5.1e-12 46.3 0.1 2.3 2 1 0 2 2 2 2 Miro-like protein Arf PF00025.16 ETO34843.1 - 5.8e-13 48.4 0.2 1.4e-09 37.4 0.2 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETO34843.1 - 8.8e-05 21.7 1.0 0.00013 21.1 0.2 1.6 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Dynamin_N PF00350.18 ETO34843.1 - 0.0056 16.5 1.9 0.02 14.6 1.3 1.9 1 1 0 1 1 1 1 Dynamin family DUF3616 PF12275.3 ETO34843.1 - 0.044 12.7 0.0 0.073 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3616) Menin PF05053.8 ETO34843.1 - 0.049 11.7 6.4 0.052 11.7 4.5 1.1 1 0 0 1 1 1 0 Menin Apis_Csd PF11671.3 ETO34843.1 - 0.14 11.9 8.6 0.24 11.1 5.9 1.5 1 0 0 1 1 1 0 Complementary sex determiner protein HECT PF00632.20 ETO34844.1 - 1.5e-93 313.4 1.4 2.1e-93 312.9 1.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) YafO_toxin PF13957.1 ETO34845.1 - 0.053 13.3 1.5 0.081 12.7 1.1 1.3 1 0 0 1 1 1 0 Toxin YafO, type II toxin-antitoxin system YMF19 PF02326.10 ETO34845.1 - 0.94 10.0 9.9 7.7 7.1 6.9 2.2 1 1 0 1 1 1 0 Plant ATP synthase F0 PEPcase_2 PF14010.1 ETO34846.1 - 0.015 13.6 0.6 0.018 13.3 0.4 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Ins134_P3_kin PF05770.6 ETO34846.1 - 0.034 13.1 0.1 0.042 12.8 0.1 1.1 1 0 0 1 1 1 0 Inositol 1, 3, 4-trisphosphate 5/6-kinase MSC PF09402.5 ETO34846.1 - 0.038 12.7 0.4 0.053 12.2 0.3 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Clusterin PF01093.12 ETO34846.1 - 0.091 11.5 0.1 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Clusterin Cas_Cas6 PF01881.11 ETO34846.1 - 0.18 12.0 0.9 0.28 11.3 0.6 1.3 1 1 0 1 1 1 0 CRISPR associated protein Cas6 Peptidase_M20 PF01546.23 ETO34847.1 - 1.8e-08 34.0 0.0 2.2e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.12 ETO34847.1 - 0.053 13.2 0.3 0.48 10.1 0.1 2.0 1 1 1 2 2 2 0 Peptidase family M28 M20_dimer PF07687.9 ETO34847.1 - 0.066 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase dimerisation domain Menin PF05053.8 ETO34848.1 - 0.33 9.0 7.5 0.58 8.2 5.2 1.4 1 0 0 1 1 1 0 Menin DUF2457 PF10446.4 ETO34848.1 - 0.35 9.5 8.1 0.57 8.8 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pox_Ag35 PF03286.9 ETO34848.1 - 0.98 8.9 10.5 2.3 7.6 7.3 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RVT_1 PF00078.22 ETO34850.1 - 5.8e-12 45.4 0.1 7.7e-11 41.7 0.1 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DSPc PF00782.15 ETO34851.1 - 4.8e-13 48.8 0.0 6.2e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 ETO34851.1 - 3.6e-07 29.7 0.0 9.6e-07 28.3 0.0 1.6 1 1 1 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 ETO34851.1 - 0.00024 21.1 0.0 0.0003 20.8 0.0 1.1 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 ETO34851.1 - 0.0073 16.5 0.0 0.009 16.2 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 ETO34851.1 - 0.046 13.0 0.1 0.066 12.5 0.1 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Mem_trans PF03547.13 ETO34852.1 - 0.98 7.6 5.1 0.98 7.6 3.5 1.2 1 0 0 1 1 1 0 Membrane transport protein Ank_2 PF12796.2 ETO34853.1 - 1.2e-15 57.5 0.1 2.6e-15 56.5 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO34853.1 - 8.1e-14 50.6 0.0 2.7e-07 30.0 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 ETO34853.1 - 3.3e-10 39.1 0.2 2.9e-05 23.8 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 ETO34853.1 - 6.3e-10 39.2 0.1 0.0011 19.4 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO34853.1 - 8.9e-08 32.1 0.2 0.00041 20.5 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) WD40 PF00400.27 ETO34854.1 - 7.7e-62 203.1 6.6 5.1e-12 45.1 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat PD40 PF07676.7 ETO34854.1 - 0.0003 20.3 4.0 9.9 5.9 0.0 5.5 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat BBS2_Mid PF14783.1 ETO34854.1 - 0.0011 18.7 4.6 3.6 7.3 0.2 4.8 2 1 3 5 5 5 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 ETO34854.1 - 0.0017 16.5 7.4 0.2 9.7 0.8 4.5 2 2 3 5 5 5 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO34854.1 - 0.0028 16.0 0.1 7.8 4.6 0.0 3.2 2 1 1 3 3 3 2 Cytochrome D1 heme domain DUF1258 PF06869.7 ETO34854.1 - 0.12 11.4 2.3 3.4 6.6 0.1 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF1258) Mid2 PF04478.7 ETO34854.1 - 0.13 11.7 10.1 0.045 13.1 2.6 3.0 2 1 2 4 4 4 0 Mid2 like cell wall stress sensor Chordopox_A13L PF05961.6 ETO34854.1 - 0.24 11.3 4.7 0.47 10.4 3.3 1.4 1 0 0 1 1 1 0 Chordopoxvirus A13L protein p450 PF00067.17 ETO34855.1 - 1.7e-08 33.4 0.5 2e-08 33.1 0.4 1.0 1 0 0 1 1 1 1 Cytochrome P450 PIR PF00399.14 ETO34856.1 - 0.26 10.7 1.6 0.56 9.6 1.1 1.5 1 0 0 1 1 1 0 Yeast PIR protein repeat RRM_1 PF00076.17 ETO34857.1 - 9.3e-10 38.0 0.1 1.5e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO34857.1 - 0.0059 16.5 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2243 PF10002.4 ETO34857.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2243) RRM_1 PF00076.17 ETO34858.1 - 1e-06 28.2 0.0 2.2e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO34858.1 - 0.00019 21.1 0.0 0.0006 19.6 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO34858.1 - 0.00031 20.6 0.0 0.001 18.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.17 ETO34859.1 - 2.1e-28 98.7 0.0 3.3e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO34859.1 - 2.3e-09 37.7 0.0 4.1e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO34859.1 - 0.0011 18.2 0.0 0.11 11.7 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family Arch_ATPase PF01637.13 ETO34859.1 - 0.026 14.2 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_25 PF13481.1 ETO34859.1 - 0.063 12.6 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 ETO34859.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.1 ETO34859.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 ETO34859.1 - 0.13 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain WD40 PF00400.27 ETO34860.1 - 3.2e-77 251.8 15.7 1.3e-12 47.0 0.1 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO34860.1 - 4.9e-06 26.4 4.2 0.006 16.7 0.1 4.2 4 1 1 5 5 5 2 Kelch motif DUF1258 PF06869.7 ETO34860.1 - 5.7e-06 25.6 0.9 0.17 10.9 0.0 4.0 2 2 2 4 4 4 2 Protein of unknown function (DUF1258) Kelch_2 PF07646.10 ETO34860.1 - 1.6e-05 24.4 2.9 0.039 13.7 0.0 3.6 4 0 0 4 4 4 2 Kelch motif Nup160 PF11715.3 ETO34860.1 - 2.6e-05 22.6 5.7 0.061 11.4 0.4 4.3 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Kelch_1 PF01344.20 ETO34860.1 - 3.9e-05 23.1 4.3 0.24 10.9 0.1 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO34860.1 - 6.6e-05 22.7 3.6 0.053 13.4 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO34860.1 - 0.0055 16.4 0.0 1 9.1 0.0 3.7 3 1 0 3 3 3 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO34860.1 - 0.012 15.7 0.0 7.2 6.9 0.0 2.8 2 0 0 2 2 2 0 Galactose oxidase, central domain WD40 PF00400.27 ETO34861.1 - 7e-62 203.2 28.3 7.7e-12 44.6 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO34861.1 - 2.3e-10 39.2 4.0 0.039 12.0 0.1 5.2 2 2 3 5 5 5 5 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO34861.1 - 0.00028 21.2 1.8 0.00028 21.2 1.2 2.7 4 0 0 4 4 4 1 TRAF-type zinc finger CCDC155 PF14662.1 ETO34861.1 - 0.69 9.4 22.9 1.3 8.5 15.9 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 IncA PF04156.9 ETO34861.1 - 0.73 9.3 14.6 1.5 8.4 10.1 1.4 1 0 0 1 1 1 0 IncA protein Nnf1 PF03980.9 ETO34863.1 - 0.33 10.9 4.6 6.5 6.7 3.2 2.4 1 1 0 1 1 1 0 Nnf1 PH PF00169.24 ETO34864.1 - 0.22 11.7 3.8 0.18 11.9 0.5 2.4 2 1 0 2 2 2 0 PH domain RhoGEF PF00621.15 ETO34865.1 - 0.00096 19.0 1.7 0.00096 19.0 1.2 1.7 1 1 1 2 2 2 1 RhoGEF domain zf-CCCH PF00642.19 ETO34866.1 - 2.2e-08 33.5 17.8 5.6e-07 29.0 3.1 3.0 2 1 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 ETO34866.1 - 0.013 15.5 9.9 0.059 13.3 1.8 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type DUF605 PF04652.11 ETO34866.1 - 5.9 6.1 30.9 9.4 5.5 21.4 1.3 1 0 0 1 1 1 0 Vta1 like Transformer PF06495.6 ETO34868.1 - 0.14 12.0 1.0 0.25 11.1 0.1 1.9 2 0 0 2 2 2 0 Fruit fly transformer protein CK2S PF15011.1 ETO34868.1 - 0.16 11.7 0.0 0.4 10.4 0.0 1.6 2 0 0 2 2 2 0 Casein Kinase 2 substrate Tim54 PF11711.3 ETO34868.1 - 6.9 5.1 17.1 0.08 11.5 1.0 2.7 3 0 0 3 3 3 0 Inner membrane protein import complex subunit Tim54 Peptidase_C23 PF05379.6 ETO34869.1 - 0.055 13.4 0.0 0.13 12.2 0.0 1.7 1 1 0 1 1 1 0 Carlavirus endopeptidase WD40 PF00400.27 ETO34870.1 - 2.8e-137 442.3 42.1 1.3e-10 40.6 0.0 15.2 15 0 0 15 15 15 15 WD domain, G-beta repeat Nup160 PF11715.3 ETO34870.1 - 4.4e-16 58.1 25.6 0.19 9.8 0.0 12.4 1 1 10 12 12 12 7 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO34870.1 - 3.4e-06 26.6 8.1 0.042 13.3 0.4 4.8 2 2 0 2 2 2 2 PQQ-like domain Pentapeptide PF00805.17 ETO34870.1 - 4.4e-06 25.8 1.4 1.5e-05 24.0 0.8 1.9 1 1 0 1 1 1 1 Pentapeptide repeats (8 copies) NYD-SP28_assoc PF14775.1 ETO34870.1 - 0.00015 21.3 9.0 46 3.8 0.0 9.5 13 0 0 13 13 13 0 Sperm tail C-terminal domain Str_synth PF03088.11 ETO34870.1 - 0.00015 21.7 0.4 9.1 6.3 0.0 6.1 5 2 2 7 7 6 1 Strictosidine synthase Pentapeptide_4 PF13599.1 ETO34870.1 - 0.00017 21.3 0.1 0.00046 19.9 0.1 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Cytochrom_D1 PF02239.11 ETO34870.1 - 0.00019 19.8 11.5 0.36 9.0 0.1 5.5 2 1 4 7 7 7 3 Cytochrome D1 heme domain Pentapeptide_3 PF13576.1 ETO34870.1 - 0.0036 17.1 1.4 0.0036 17.1 0.9 2.6 3 1 0 3 3 2 1 Pentapeptide repeats (9 copies) Peptidase_C69 PF03577.10 ETO34870.1 - 0.0085 15.0 2.0 14 4.4 0.0 4.8 5 0 0 5 5 5 0 Peptidase family C69 PD40 PF07676.7 ETO34870.1 - 0.016 14.8 12.5 25 4.6 0.0 7.1 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat Mid2 PF04478.7 ETO34870.1 - 0.023 14.1 19.7 5.4 6.4 0.0 8.4 3 3 5 10 10 10 0 Mid2 like cell wall stress sensor DUF727 PF05303.7 ETO34870.1 - 0.039 13.7 1.5 20 5.0 0.0 5.1 6 1 1 7 7 6 0 Protein of unknown function (DUF727) SoxZ PF08770.6 ETO34870.1 - 0.074 12.4 0.5 2.6 7.5 0.0 3.7 5 0 0 5 5 5 0 Sulphur oxidation protein SoxZ PLD_C PF12357.3 ETO34870.1 - 0.08 12.4 0.1 1e+02 2.5 0.0 5.3 8 0 0 8 8 8 0 Phospholipase D C terminal Kelch_5 PF13854.1 ETO34871.1 - 0.00057 19.7 0.0 0.53 10.3 0.0 2.9 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.1 ETO34871.1 - 0.035 14.2 0.1 4.5 7.6 0.0 2.7 3 0 0 3 3 3 0 Kelch motif WD40 PF00400.27 ETO34872.1 - 4.7e-65 213.3 14.0 3.4e-12 45.7 0.3 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO34872.1 - 1.2e-14 54.5 0.4 1.8e-07 31.1 0.1 3.0 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 ETO34872.1 - 1.2e-05 24.3 10.2 0.065 11.9 1.1 4.2 1 1 2 3 3 3 3 Nup133 N terminal like DUF1258 PF06869.7 ETO34872.1 - 0.00044 19.4 0.6 0.2 10.6 0.0 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF1258) B_lectin PF01453.19 ETO34872.1 - 0.0006 19.6 0.8 0.0016 18.2 0.3 1.9 1 1 1 2 2 2 2 D-mannose binding lectin SGL PF08450.7 ETO34872.1 - 0.0017 17.7 0.2 0.015 14.7 0.0 2.3 1 1 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Nbas_N PF15492.1 ETO34872.1 - 0.004 16.2 2.9 0.48 9.4 0.0 3.2 1 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 ETO34872.1 - 0.0053 16.2 0.4 0.021 14.2 0.0 2.1 2 1 0 2 2 2 1 PQQ-like domain Proteasome_A_N PF10584.4 ETO34872.1 - 0.39 10.0 2.6 2.8 7.3 0.0 3.4 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature MutH PF02976.10 ETO34874.1 - 0.029 14.2 1.4 0.045 13.6 1.0 1.4 1 1 0 1 1 1 0 DNA mismatch repair enzyme MutH Exo_endo_phos PF03372.18 ETO34875.1 - 6.9e-14 52.3 0.0 9.4e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DDHD PF02862.12 ETO34875.1 - 0.18 11.6 3.5 0.33 10.7 2.4 1.4 1 0 0 1 1 1 0 DDHD domain Mem_trans PF03547.13 ETO34875.1 - 0.2 9.9 0.7 0.27 9.5 0.5 1.1 1 0 0 1 1 1 0 Membrane transport protein Trypan_PARP PF05887.6 ETO34875.1 - 5.6 6.7 7.4 8.7 6.1 5.1 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) C2 PF00168.25 ETO34876.1 - 0.00099 18.9 0.1 0.0022 17.7 0.1 1.7 1 1 0 1 1 1 1 C2 domain CENP-B_dimeris PF09026.5 ETO34876.1 - 0.027 14.6 2.1 0.027 14.6 1.5 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Hid1 PF12722.2 ETO34876.1 - 0.77 7.3 10.1 0.94 7.0 7.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CAF1A PF12253.3 ETO34876.1 - 1.8 8.7 10.1 0.09 12.8 2.9 1.9 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A Pap_E4 PF02711.9 ETO34876.1 - 2.5 8.9 11.3 8.7 7.2 0.5 2.4 2 0 0 2 2 2 0 E4 protein Striatin PF08232.7 ETO34876.1 - 2.9 8.2 11.4 6.6 7.0 2.5 2.2 2 0 0 2 2 2 0 Striatin family Mito_fiss_reg PF05308.6 ETO34876.1 - 3.9 6.7 8.6 5.4 6.3 5.9 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator PBP1_TM PF14812.1 ETO34876.1 - 8.1 6.8 9.8 2.2 8.6 0.7 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WD40 PF00400.27 ETO34877.1 - 1.2e-168 541.7 44.9 4e-12 45.5 0.5 16.4 16 0 0 16 16 16 16 WD domain, G-beta repeat NACHT PF05729.7 ETO34877.1 - 7e-10 38.8 0.0 1.4e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.7 ETO34877.1 - 1.9e-06 27.3 13.7 1.9 8.2 0.0 8.5 9 0 0 9 9 9 1 WD40-like Beta Propeller Repeat Pentapeptide PF00805.17 ETO34877.1 - 1.5e-05 24.0 0.5 2.7e-05 23.2 0.4 1.4 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) DUF1938 PF09153.5 ETO34877.1 - 3.2e-05 23.6 2.1 1.7 8.5 0.0 5.2 4 1 1 5 5 5 1 Domain of unknown function (DUF1938) Pentapeptide_4 PF13599.1 ETO34877.1 - 4.5e-05 23.1 3.4 0.00013 21.6 2.3 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA_18 PF13238.1 ETO34877.1 - 0.00013 22.2 4.6 0.00015 22.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain NYD-SP28_assoc PF14775.1 ETO34877.1 - 0.00022 20.8 15.1 27 4.5 0.0 10.9 15 0 0 15 15 13 0 Sperm tail C-terminal domain AAA_22 PF13401.1 ETO34877.1 - 0.00028 21.0 0.0 0.00073 19.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO34877.1 - 0.00038 21.2 1.2 0.0096 16.7 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA PF00004.24 ETO34877.1 - 0.003 17.7 0.2 0.1 12.8 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Pentapeptide_3 PF13576.1 ETO34877.1 - 0.0036 17.1 3.2 0.012 15.4 1.0 2.4 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) UPF0079 PF02367.12 ETO34877.1 - 0.04 13.5 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 ETO34877.1 - 0.12 12.2 0.0 0.35 10.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Kelch_3 PF13415.1 ETO34878.1 - 1e-06 28.7 0.0 0.26 11.4 0.0 4.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO34878.1 - 3.3e-05 23.3 0.7 0.24 10.9 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 ETO34878.1 - 0.00023 21.0 1.1 0.51 10.3 0.2 3.1 3 0 0 3 3 3 2 Kelch motif DUF1699 PF08004.6 ETO34878.1 - 0.00095 18.6 0.0 0.0021 17.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1699) Kelch_6 PF13964.1 ETO34878.1 - 0.0012 18.8 2.9 0.29 11.3 0.1 3.7 3 1 1 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO34878.1 - 0.0018 18.0 0.9 1.1 9.0 0.0 2.6 1 1 1 2 2 2 2 Galactose oxidase, central domain DUF4440 PF14534.1 ETO34878.1 - 0.058 13.6 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) WD40 PF00400.27 ETO34879.1 - 9.6e-26 88.6 4.7 9.8e-09 34.7 0.1 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat DPPIV_N PF00930.16 ETO34879.1 - 2.5e-06 26.3 0.5 0.14 10.6 0.0 3.0 1 1 2 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nup160 PF11715.3 ETO34879.1 - 3.7e-06 25.3 0.6 0.21 9.7 0.0 3.4 1 1 2 3 3 3 3 Nucleoporin Nup120/160 PD40 PF07676.7 ETO34879.1 - 0.00033 20.2 5.7 3.1 7.5 0.0 5.0 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.9 ETO34879.1 - 0.00059 18.7 2.1 0.062 12.0 0.2 2.1 1 1 1 2 2 2 2 Coatomer WD associated region Imm21 PF15569.1 ETO34879.1 - 0.0046 16.6 0.2 3 7.6 0.0 3.4 2 1 1 3 3 3 1 Immunity protein 21 Pectate_lyase22 PF14583.1 ETO34879.1 - 0.023 13.1 0.0 6.7 5.0 0.0 2.8 1 1 2 3 3 3 0 Oligogalacturonate lyase TAN PF11640.3 ETO34879.1 - 0.028 14.1 0.3 0.044 13.5 0.2 1.4 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair DUF1938 PF09153.5 ETO34879.1 - 0.03 14.1 0.2 0.079 12.7 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1938) BetaGal_dom2 PF10435.4 ETO34879.1 - 0.037 13.3 0.0 0.46 9.8 0.0 2.1 1 1 1 2 2 2 0 Beta-galactosidase, domain 2 Peptidase_C69 PF03577.10 ETO34879.1 - 0.14 10.9 0.4 2.5 6.8 0.0 2.0 1 1 1 2 2 2 0 Peptidase family C69 WD40 PF00400.27 ETO34880.1 - 2.6e-60 198.2 24.3 4.3e-10 39.0 0.3 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO34880.1 - 4.2e-09 35.0 10.6 0.03 12.4 0.2 5.3 2 2 3 6 6 6 5 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO34880.1 - 0.0014 18.9 2.7 0.0014 18.9 1.9 2.6 3 0 0 3 3 3 1 TRAF-type zinc finger fn3 PF00041.16 ETO34882.1 - 0.11 12.6 4.9 0.15 12.2 0.3 3.4 2 1 1 3 3 3 0 Fibronectin type III domain G_glu_transpept PF01019.16 ETO34883.1 - 9.6e-35 120.0 0.0 1.1e-34 119.8 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Dynein_heavy PF03028.10 ETO34884.1 - 9.7e-154 513.1 1.1 3.1e-100 336.2 0.2 2.0 2 0 0 2 2 2 2 Dynein heavy chain and region D6 of dynein motor Mu-like_Com PF10122.4 ETO34884.1 - 0.098 11.7 0.0 7.7 5.6 0.0 2.4 2 0 0 2 2 2 0 Mu-like prophage protein Com DUF3772 PF12607.3 ETO34885.1 - 0.077 12.6 1.1 0.11 12.1 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) Guanylate_kin PF00625.16 ETO34885.1 - 0.083 12.3 0.2 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Guanylate kinase Peptidase_C14 PF00656.17 ETO34886.1 - 0.0024 17.6 0.0 0.003 17.2 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Phage_int_SAM_4 PF13495.1 ETO34886.1 - 0.12 12.6 0.1 0.2 12.0 0.1 1.3 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Ank_2 PF12796.2 ETO34887.1 - 1.6e-41 140.5 11.9 3.8e-16 59.2 0.3 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 ETO34887.1 - 2.5e-25 86.9 0.0 2.4e-06 27.0 0.0 7.6 7 1 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 ETO34887.1 - 1.6e-20 72.6 0.5 1.7e-09 37.6 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO34887.1 - 4.8e-19 66.5 0.6 0.0027 17.8 0.0 7.2 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.1 ETO34887.1 - 5.6e-18 64.9 1.6 1.1e-05 25.8 0.0 5.5 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Kelch_6 PF13964.1 ETO34888.1 - 0.054 13.6 0.3 0.81 9.9 0.0 2.6 3 0 0 3 3 3 0 Kelch motif Kelch_1 PF01344.20 ETO34889.1 - 4.8e-05 22.8 0.2 0.00027 20.4 0.1 2.1 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETO34889.1 - 0.00015 21.7 2.0 0.0021 18.1 0.1 2.7 2 1 1 3 3 3 1 Kelch motif Kelch_3 PF13415.1 ETO34889.1 - 0.00021 21.3 0.0 0.00079 19.5 0.0 2.0 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO34889.1 - 0.00041 20.0 2.8 0.0085 15.8 0.0 2.9 3 0 0 3 3 3 1 Galactose oxidase, central domain UPF0172 PF03665.8 ETO34889.1 - 0.0028 17.1 1.3 0.0039 16.6 0.9 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) DUF342 PF03961.8 ETO34889.1 - 0.0073 14.7 5.4 0.0087 14.5 3.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) Kelch_5 PF13854.1 ETO34889.1 - 0.021 14.7 0.4 0.17 11.8 0.1 2.2 2 0 0 2 2 2 0 Kelch motif Kelch_2 PF07646.10 ETO34889.1 - 0.086 12.6 0.3 2.3 8.1 0.1 2.6 2 0 0 2 2 2 0 Kelch motif UvrD-helicase PF00580.16 ETO34889.1 - 0.088 12.0 3.5 0.1 11.8 2.4 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Kelch_6 PF13964.1 ETO34890.1 - 0.14 12.3 0.4 23 5.3 0.1 2.2 2 0 0 2 2 2 0 Kelch motif Kelch_6 PF13964.1 ETO34892.1 - 3.5e-06 26.9 4.8 0.18 12.0 0.3 4.6 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO34892.1 - 3.9e-06 26.2 5.7 0.015 14.8 0.6 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO34892.1 - 1.7e-05 24.3 6.9 0.0052 16.4 0.3 4.4 5 1 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO34892.1 - 0.00013 21.6 1.7 0.42 10.4 0.1 3.7 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO34892.1 - 0.0018 18.1 7.5 0.9 9.5 0.0 4.5 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 ETO34892.1 - 0.017 15.2 0.1 0.66 10.2 0.0 3.2 4 0 0 4 4 4 0 Galactose oxidase, central domain FlbT PF07378.6 ETO34893.1 - 0.078 12.8 0.1 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Flagellar protein FlbT PsiE PF06146.7 ETO34893.1 - 0.082 13.1 0.7 0.082 13.1 0.5 1.8 2 0 0 2 2 2 0 Phosphate-starvation-inducible E Lipoprotein_19 PF13617.1 ETO34894.1 - 0.1 12.2 1.6 0.31 10.6 1.1 1.8 1 0 0 1 1 1 0 YnbE-like lipoprotein Cupredoxin_1 PF13473.1 ETO34894.1 - 0.33 10.8 2.1 2.7 7.9 0.2 2.5 1 1 1 2 2 2 0 Cupredoxin-like domain CLASP_N PF12348.3 ETO34895.1 - 6.2e-07 28.9 0.1 8.3e-07 28.5 0.1 1.1 1 0 0 1 1 1 1 CLASP N terminal FANCF PF11107.3 ETO34895.1 - 0.081 12.1 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) CLASP_N PF12348.3 ETO34896.1 - 1.1e-11 44.6 3.6 7.9e-05 22.1 0.2 2.8 2 1 0 2 2 2 2 CLASP N terminal Myb_DNA-bind_3 PF12776.2 ETO34896.1 - 0.22 12.2 0.1 0.22 12.2 0.0 2.5 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain 7TM_GPCR_Srv PF10323.4 ETO34896.1 - 0.27 10.3 3.1 0.53 9.3 2.1 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv Spore_III_AB PF09548.5 ETO34896.1 - 0.66 9.7 4.9 0.097 12.4 0.5 1.8 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) PBP1_TM PF14812.1 ETO34896.1 - 9 6.6 7.3 20 5.5 0.8 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PH PF00169.24 ETO34897.1 - 2.8e-08 33.8 1.6 9.7e-08 32.1 0.4 2.5 2 1 0 2 2 2 1 PH domain SAM_1 PF00536.25 ETO34897.1 - 5.1e-08 32.9 0.1 1e-07 32.0 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO34897.1 - 6e-06 26.0 0.1 1.1e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 ETO34897.1 - 0.0015 18.2 0.3 0.003 17.2 0.2 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain PH_11 PF15413.1 ETO34897.1 - 0.0048 17.1 0.3 0.017 15.3 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.1 ETO34897.1 - 0.0081 16.0 0.1 0.03 14.2 0.0 2.0 2 0 0 2 2 2 1 PH domain Nucleoplasmin PF03066.10 ETO34897.1 - 6.2 6.3 10.3 35 3.8 4.5 2.3 2 0 0 2 2 2 0 Nucleoplasmin Aa_trans PF01490.13 ETO34898.1 - 5.9e-06 25.0 4.1 5.9e-06 25.0 2.9 1.8 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 ETO34898.1 - 2.5e-05 23.2 0.6 4e-05 22.6 0.4 1.2 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Cytochrom_B_N_2 PF13631.1 ETO34898.1 - 0.37 10.5 3.2 0.91 9.2 0.7 2.0 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB TraU PF06834.6 ETO34899.1 - 0.56 9.2 2.8 0.2 10.7 0.1 1.5 2 0 0 2 2 2 0 TraU protein DUF3513 PF12026.3 ETO34899.1 - 2.2 7.7 8.3 4 6.9 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3513) AhpC-TSA PF00578.16 ETO34900.1 - 0.018 14.6 0.1 0.037 13.7 0.1 1.4 1 0 0 1 1 1 0 AhpC/TSA family Snurportin1 PF11538.3 ETO34906.1 - 0.1 12.3 5.7 0.21 11.3 3.9 1.4 1 0 0 1 1 1 0 Snurportin1 zf-NF-X1 PF01422.12 ETO34907.1 - 0.013 15.3 11.9 0.013 15.3 8.2 5.7 6 1 0 6 6 6 0 NF-X1 type zinc finger U-box PF04564.10 ETO34908.1 - 1.5e-10 40.8 0.6 6.6e-10 38.8 0.0 2.5 2 1 0 2 2 2 1 U-box domain Kelch_1 PF01344.20 ETO34908.1 - 1.1e-05 24.8 0.4 0.00016 21.1 0.0 2.9 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETO34908.1 - 4.8e-05 23.0 0.0 0.0023 17.6 0.0 2.8 2 1 0 2 2 2 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO34908.1 - 0.00042 20.3 0.4 0.0091 16.1 0.1 2.9 1 1 1 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO34908.1 - 0.012 15.7 0.0 0.059 13.5 0.0 2.2 2 0 0 2 2 2 0 Galactose oxidase, central domain DASH_Dad3 PF08656.5 ETO34908.1 - 0.028 14.0 2.3 2 8.2 0.1 2.9 2 0 0 2 2 2 0 DASH complex subunit Dad3 Hemocyanin_N PF03722.9 ETO34908.1 - 1.7 8.8 7.1 1.2 9.3 0.2 3.6 3 2 0 3 3 3 0 Hemocyanin, all-alpha domain HEAT_2 PF13646.1 ETO34909.1 - 2.7e-14 53.1 0.0 0.00067 19.8 0.0 4.5 3 2 1 4 4 4 3 HEAT repeats HEAT PF02985.17 ETO34909.1 - 1.5e-12 46.4 0.2 0.0093 15.9 0.0 6.4 6 1 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 ETO34909.1 - 6.6e-08 32.8 0.0 0.0033 17.8 0.0 3.6 3 0 0 3 3 3 2 HEAT-like repeat TIP120 PF08623.5 ETO34909.1 - 1.4e-06 28.0 12.8 0.16 11.5 0.0 5.1 3 2 2 5 5 5 3 TATA-binding protein interacting (TIP20) Cnd1 PF12717.2 ETO34909.1 - 1.6e-06 28.1 15.4 0.086 12.6 0.1 4.5 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 ETO34909.1 - 0.0043 17.4 5.9 1.4 9.3 0.1 4.7 3 2 1 4 4 4 1 Vacuolar 14 Fab1-binding region DUF3554 PF12074.3 ETO34909.1 - 0.0096 15.3 6.2 0.14 11.5 0.2 3.4 3 2 1 4 4 4 2 Domain of unknown function (DUF3554) DUF2435 PF10363.4 ETO34909.1 - 0.012 15.4 7.4 0.95 9.4 0.0 4.8 4 1 1 5 5 5 0 Protein of unknown function (DUF2435) IPK PF03770.11 ETO34909.1 - 0.039 13.6 3.8 0.097 12.3 0.0 3.0 3 1 0 3 3 3 0 Inositol polyphosphate kinase Ndc1_Nup PF09531.5 ETO34909.1 - 0.08 11.3 1.2 1.6 7.0 0.0 3.0 4 0 0 4 4 4 0 Nucleoporin protein Ndc1-Nup Imm16 PF15565.1 ETO34909.1 - 0.12 12.2 4.8 0.5 10.2 0.1 3.7 3 1 1 4 4 4 0 Immunity protein 16 DUF3944 PF13099.1 ETO34909.1 - 0.2 11.1 0.1 0.2 11.1 0.1 5.8 7 0 0 7 7 7 0 Domain of unknown function (DUF3944) Nucleoporin_N PF08801.6 ETO34911.1 - 0.031 13.0 0.1 0.095 11.4 0.0 1.6 1 1 0 1 1 1 0 Nup133 N terminal like PD40 PF07676.7 ETO34911.1 - 0.031 13.9 0.1 4.3 7.1 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 ETO34911.1 - 0.15 11.4 0.1 5.9 6.3 0.1 2.4 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature N6_Mtase PF02384.11 ETO34912.1 - 1.4e-32 113.0 0.2 2.1e-31 109.1 0.2 2.0 1 1 0 1 1 1 1 N-6 DNA Methylase Methyltransf_26 PF13659.1 ETO34912.1 - 1.9e-11 44.0 0.0 2.7e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 ETO34912.1 - 6.2e-06 25.9 0.0 9e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Eco57I PF07669.6 ETO34912.1 - 0.00017 21.9 0.1 0.00052 20.3 0.1 1.8 1 0 0 1 1 1 1 Eco57I restriction-modification methylase Methyltransf_31 PF13847.1 ETO34912.1 - 0.0012 18.4 0.5 0.0023 17.5 0.1 1.8 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 ETO34912.1 - 0.0012 18.2 0.0 0.0051 16.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 ETO34912.1 - 0.011 16.3 0.0 0.025 15.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Virulence_RhuM PF13310.1 ETO34912.1 - 0.013 14.5 0.2 0.019 13.9 0.2 1.3 1 0 0 1 1 1 0 Virulence protein RhuM family DUF2951 PF11166.3 ETO34912.1 - 0.058 13.2 1.5 3.2 7.6 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) FKBP_C PF00254.23 ETO34912.1 - 0.073 13.0 0.3 0.32 11.0 0.0 2.0 2 1 0 2 2 2 0 FKBP-type peptidyl-prolyl cis-trans isomerase PHB_acc_N PF07879.6 ETO34913.1 - 2.9e-26 90.9 4.0 6.4e-26 89.8 2.8 1.6 1 0 0 1 1 1 1 PHB/PHA accumulation regulator DNA-binding domain Proteasome PF00227.21 ETO34913.1 - 1.9e-10 40.3 0.0 9.4e-10 38.0 0.0 2.1 2 1 0 2 2 2 1 Proteasome subunit PHB_acc PF05233.8 ETO34913.1 - 4.5e-09 35.8 0.3 2.7e-08 33.3 0.0 2.4 2 0 0 2 2 2 1 PHB accumulation regulatory domain Pribosyltran PF00156.22 ETO34913.1 - 0.00067 19.3 0.0 0.0022 17.7 0.0 1.9 1 0 0 1 1 1 1 Phosphoribosyl transferase domain TPK_catalytic PF04263.11 ETO34914.1 - 9.2e-11 41.3 0.1 1.8e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain Abhydrolase_6 PF12697.2 ETO34914.1 - 4.2e-05 23.5 0.0 7.6e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PhaC_N PF07167.8 ETO34914.1 - 0.00027 20.4 0.1 0.00077 18.9 0.0 1.8 1 0 0 1 1 1 1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Abhydrolase_1 PF00561.15 ETO34914.1 - 0.0004 20.0 0.0 0.0016 18.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold FTH PF01827.22 ETO34914.1 - 0.0033 17.0 2.1 0.013 15.0 0.3 2.6 3 0 0 3 3 3 1 FTH domain DUF3141 PF11339.3 ETO34914.1 - 0.0076 14.6 0.6 0.013 13.8 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3141) DLH PF01738.13 ETO34914.1 - 0.024 13.9 0.0 0.16 11.2 0.0 2.3 3 0 0 3 3 3 0 Dienelactone hydrolase family Esterase PF00756.15 ETO34914.1 - 0.053 12.9 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative esterase OMP_b-brl PF13505.1 ETO34915.1 - 3.7e-14 53.0 1.5 4.1e-14 52.8 1.1 1.0 1 0 0 1 1 1 1 Outer membrane protein beta-barrel domain OMP_b-brl_2 PF13568.1 ETO34915.1 - 1.5e-06 28.1 1.8 2e-06 27.7 1.3 1.1 1 0 0 1 1 1 1 Outer membrane protein beta-barrel domain Autotransporter PF03797.14 ETO34915.1 - 0.043 13.1 0.0 0.081 12.2 0.0 1.4 1 1 0 1 1 1 0 Autotransporter beta-domain OMP_b-brl PF13505.1 ETO34916.1 - 2.2e-15 57.0 1.8 2.5e-15 56.8 1.3 1.0 1 0 0 1 1 1 1 Outer membrane protein beta-barrel domain OMP_b-brl_2 PF13568.1 ETO34916.1 - 0.0022 17.8 2.4 0.003 17.3 1.6 1.3 1 0 0 1 1 1 1 Outer membrane protein beta-barrel domain Autotransporter PF03797.14 ETO34916.1 - 0.07 12.4 0.0 0.18 11.1 0.0 1.5 1 1 0 1 1 1 0 Autotransporter beta-domain Rep_3 PF01051.16 ETO34917.1 - 0.0013 18.3 0.4 0.0013 18.3 0.3 1.6 2 0 0 2 2 2 1 Initiator Replication protein UDPG_MGDP_dh_N PF03721.9 ETO34918.1 - 2e-25 89.2 0.4 2.8e-25 88.7 0.3 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 ETO34918.1 - 1.2e-14 54.2 0.0 2.6e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain TelA PF05816.6 ETO34918.1 - 0.0071 15.0 0.1 0.0094 14.6 0.1 1.1 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) DUF2659 PF10858.3 ETO34918.1 - 0.067 12.5 2.0 2.6 7.3 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2659) Glycos_transf_1 PF00534.15 ETO34919.1 - 1.9e-22 79.4 0.0 3.2e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 ETO34919.1 - 6.3e-12 45.8 0.0 1e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 ETO34919.1 - 0.012 15.8 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 L_protein_N PF15518.1 ETO34919.1 - 0.015 14.7 0.5 0.031 13.6 0.4 1.5 1 0 0 1 1 1 0 L protein N-terminus Glyco_transf_20 PF00982.16 ETO34919.1 - 0.029 12.8 0.0 0.054 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 20 SIS PF01380.17 ETO34920.1 - 1.2e-52 176.9 0.2 3.2e-30 104.4 0.1 2.8 3 0 0 3 3 3 2 SIS domain GATase_6 PF13522.1 ETO34920.1 - 1.5e-11 44.4 0.0 2.5e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 ETO34920.1 - 3.7e-11 42.8 0.0 8.6e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 ETO34920.1 - 1.1e-07 30.8 0.0 0.002 16.9 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II SIS_2 PF13580.1 ETO34920.1 - 0.0016 18.1 0.0 0.0047 16.6 0.0 1.8 1 0 0 1 1 1 1 SIS domain SPOR PF05036.8 ETO34920.1 - 0.11 12.6 0.0 0.31 11.2 0.0 1.8 1 0 0 1 1 1 0 Sporulation related domain AIRS PF00586.19 ETO34920.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 AIR synthase related protein, N-terminal domain DUF4119 PF13494.1 ETO34921.1 - 0.086 12.8 2.3 0.12 12.3 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF4119) DnaJ PF00226.26 ETO34925.1 - 1e-05 25.1 0.0 2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 ETO34925.1 - 0.0039 16.9 0.0 0.0054 16.5 0.0 1.2 1 0 0 1 1 1 1 Pam16 Tubulin_C PF03953.12 ETO34926.1 - 8.7e-12 45.1 0.1 1.1e-11 44.8 0.1 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain CBM_5_12_2 PF14600.1 ETO34927.1 - 0.097 12.3 1.4 0.24 11.0 1.0 1.6 1 0 0 1 1 1 0 Cellulose-binding domain WD40 PF00400.27 ETO34928.1 - 3.9e-23 80.4 1.7 3.8e-11 42.4 0.0 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO34928.1 - 1.2e-05 23.7 0.0 0.029 12.5 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 SGS PF05002.10 ETO34929.1 - 1.6e-23 82.2 5.1 1.6e-23 82.2 3.5 1.8 2 0 0 2 2 2 1 SGS domain CS PF04969.11 ETO34929.1 - 1.7e-09 38.1 0.8 3.2e-09 37.2 0.6 1.5 1 0 0 1 1 1 1 CS domain Arf PF00025.16 ETO34930.1 - 3.7e-75 250.9 0.1 4.4e-75 250.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 ETO34930.1 - 1e-12 47.7 0.0 1.2e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 ETO34930.1 - 1.6e-12 47.0 0.0 2.1e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 ETO34930.1 - 2.6e-10 39.5 1.7 3.3e-08 32.6 0.1 2.4 1 1 2 3 3 3 2 G-protein alpha subunit Gtr1_RagA PF04670.7 ETO34930.1 - 4.9e-09 35.6 0.0 5.7e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 ETO34930.1 - 1.8e-08 34.8 0.0 6.9e-08 33.0 0.0 1.8 1 1 1 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 ETO34930.1 - 1.9e-05 24.5 0.2 3.7e-05 23.6 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 ETO34930.1 - 0.023 14.5 0.2 0.065 13.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.13 ETO34930.1 - 0.023 13.7 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DBD_Tnp_Mut PF03108.10 ETO34930.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 MuDR family transposase zf-RING_2 PF13639.1 ETO34931.1 - 9.1e-10 38.2 5.3 9.1e-10 38.2 3.7 2.6 2 1 0 2 2 2 1 Ring finger domain Zip PF02535.17 ETO34931.1 - 0.0031 16.5 0.0 0.0038 16.2 0.0 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Folate_carrier PF01770.13 ETO34931.1 - 0.0043 15.6 0.1 0.0066 15.0 0.1 1.2 1 0 0 1 1 1 1 Reduced folate carrier zf-C3HC4_2 PF13923.1 ETO34931.1 - 0.0068 16.4 5.2 0.0068 16.4 3.6 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO34931.1 - 0.0083 15.7 1.6 0.0083 15.7 1.1 2.6 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO34931.1 - 0.022 14.4 1.7 0.022 14.4 1.2 2.2 2 1 0 2 2 1 0 zinc-RING finger domain RIC3 PF15361.1 ETO34931.1 - 0.073 13.2 0.5 0.15 12.2 0.4 1.5 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 zf-rbx1 PF12678.2 ETO34931.1 - 0.1 12.7 6.5 0.051 13.6 2.6 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger Pox_Ag35 PF03286.9 ETO34931.1 - 0.25 10.8 7.0 0.34 10.4 4.9 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Di19_C PF14571.1 ETO34931.1 - 0.38 11.0 4.9 0.56 10.5 3.4 1.2 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal zf-RING_UBOX PF13445.1 ETO34931.1 - 2.6 7.8 7.6 0.21 11.3 1.0 2.4 2 0 0 2 2 2 0 RING-type zinc-finger PT PF04886.7 ETO34933.1 - 4.3e-38 128.3 130.4 2.8e-06 26.5 15.2 8.3 1 1 2 3 3 3 2 PT repeat NACHT PF05729.7 ETO34934.1 - 5.8e-08 32.5 0.0 1.3e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO34934.1 - 3.7e-05 24.0 0.2 0.00022 21.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETO34934.1 - 0.0021 18.1 0.0 0.0073 16.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO34934.1 - 0.0047 17.7 0.1 0.039 14.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain RelA_SpoT PF04607.12 ETO34934.1 - 0.0087 16.0 1.6 0.019 14.9 0.2 2.2 2 0 0 2 2 2 1 Region found in RelA / SpoT proteins TerB-C PF15615.1 ETO34935.1 - 0.008 16.4 1.4 0.19 11.9 0.0 2.7 2 1 1 3 3 3 1 TerB-C domain zf-LITAF-like PF10601.4 ETO34935.1 - 0.1 12.4 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain DUF1610 PF07754.6 ETO34935.1 - 0.14 12.2 0.8 1.8 8.7 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) YxiJ PF14176.1 ETO34935.1 - 0.3 11.2 1.9 6.3 6.9 0.0 2.7 2 2 0 2 2 2 0 YxiJ-like protein zf-TRAF PF02176.13 ETO34936.1 - 1.8e-05 25.0 12.3 0.012 15.9 1.0 3.3 3 0 0 3 3 3 3 TRAF-type zinc finger Sfi1_C PF10638.4 ETO34936.1 - 0.0055 17.1 0.5 0.013 15.9 0.4 1.6 1 0 0 1 1 1 1 Spindle body associated protein C-terminus Sgf11 PF08209.6 ETO34936.1 - 0.0071 15.6 1.6 6.1 6.2 0.1 3.3 3 0 0 3 3 3 2 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 ETO34936.1 - 0.012 15.3 4.8 2 8.1 0.0 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C3HC4_3 PF13920.1 ETO34936.1 - 0.038 13.6 5.5 9.1 6.0 0.1 3.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-Di19 PF05605.7 ETO34936.1 - 0.068 13.2 8.9 4.4 7.5 0.6 3.4 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding RPA_interact_C PF14768.1 ETO34936.1 - 0.079 13.3 10.5 3.4 8.1 0.1 3.8 3 1 0 3 3 3 0 Replication protein A interacting C-terminal DUF329 PF03884.9 ETO34936.1 - 0.083 12.4 5.6 5.7 6.5 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF329) zf-RING_5 PF14634.1 ETO34936.1 - 1.5 8.5 6.7 27 4.5 0.1 3.5 3 0 0 3 3 3 0 zinc-RING finger domain NACHT PF05729.7 ETO34937.1 - 4.4e-20 71.9 0.0 8.3e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 ETO34937.1 - 3.8e-07 29.2 4.5 6.1e-07 28.5 0.5 2.4 2 1 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.1 ETO34937.1 - 0.0013 18.8 0.0 0.0045 17.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETO34937.1 - 0.0034 17.1 0.0 0.006 16.3 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 ETO34937.1 - 0.015 15.5 0.2 0.015 15.5 0.1 3.2 2 1 1 3 3 3 0 AAA domain PhoH PF02562.11 ETO34937.1 - 0.022 13.9 0.0 1.4 8.1 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_16 PF13191.1 ETO34937.1 - 0.035 14.0 0.0 0.45 10.4 0.0 2.3 1 1 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 ETO34937.1 - 0.053 13.6 0.1 1.1 9.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DUF4014 PF13198.1 ETO34937.1 - 0.054 13.9 0.1 0.22 11.9 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4014) AAA_25 PF13481.1 ETO34937.1 - 0.072 12.4 0.0 0.69 9.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain PC_rep PF01851.17 ETO34938.1 - 1.1e-08 34.8 4.1 1.5e-05 24.9 0.0 4.1 3 1 0 3 3 3 2 Proteasome/cyclosome repeat Adaptin_N PF01602.15 ETO34938.1 - 0.088 11.1 0.0 0.14 10.4 0.0 1.2 1 0 0 1 1 1 0 Adaptin N terminal region DUF2203 PF09969.4 ETO34939.1 - 0.024 14.8 0.9 0.05 13.8 0.5 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) TBPIP PF07106.8 ETO34939.1 - 0.028 13.9 5.2 0.042 13.4 3.6 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Ribosomal_L12 PF00542.14 ETO34939.1 - 0.057 13.4 0.5 6.1 6.9 0.0 2.3 1 1 1 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain Imm46 PF15585.1 ETO34939.1 - 0.096 12.7 0.5 0.15 12.1 0.3 1.3 1 0 0 1 1 1 0 Immunity protein 46 GrpE PF01025.14 ETO34939.1 - 0.18 11.3 3.2 0.28 10.7 2.2 1.2 1 0 0 1 1 1 0 GrpE SpoU_sub_bind PF08032.7 ETO34939.1 - 0.21 11.7 1.1 0.46 10.6 0.4 1.8 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding DUF4296 PF14129.1 ETO34940.1 - 0.026 14.6 0.4 0.055 13.6 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4296) SAM_2 PF07647.12 ETO34940.1 - 0.041 13.7 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF2217 PF10265.4 ETO34940.1 - 2.2 6.9 5.5 0.99 8.0 2.4 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) HAD PF12710.2 ETO34941.1 - 1.7e-17 64.2 0.0 5.6e-17 62.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 ETO34941.1 - 3.5e-14 53.7 0.1 1.5e-05 25.5 0.0 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETO34941.1 - 5.9e-10 38.9 0.4 2.7e-09 36.8 0.2 2.3 2 1 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 ETO34941.1 - 0.0063 16.1 0.4 0.0063 16.1 0.3 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 ETO34942.1 - 7.8e-05 21.8 0.0 8.8e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 E1-E2 ATPase WD40 PF00400.27 ETO34943.1 - 4e-39 131.1 13.8 1.3e-11 43.9 0.5 5.9 6 1 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO34943.1 - 1.2e-07 30.2 0.4 0.017 13.2 0.0 3.9 2 1 1 4 4 4 4 Nucleoporin Nup120/160 PX PF00787.19 ETO34944.1 - 5.1e-07 29.4 0.4 1.1e-06 28.3 0.3 1.6 1 1 0 1 1 1 1 PX domain SAPS PF04499.10 ETO34945.1 - 0.00036 19.3 2.5 0.00036 19.3 1.8 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein MIP-T3 PF10243.4 ETO34945.1 - 0.053 11.9 26.5 0.066 11.6 18.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1777 PF08648.7 ETO34945.1 - 0.11 12.1 19.5 0.15 11.7 13.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Neur_chan_memb PF02932.11 ETO34945.1 - 0.82 9.5 7.0 1.1 9.0 4.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SDA1 PF05285.7 ETO34945.1 - 1 8.6 27.3 1.2 8.2 18.9 1.1 1 0 0 1 1 1 0 SDA1 DUF2151 PF10221.4 ETO34945.1 - 2.1 6.4 21.1 1.1 7.2 12.5 1.8 2 0 0 2 2 2 0 Cell cycle and development regulator Suf PF05843.9 ETO34945.1 - 2.5 7.7 14.8 3.8 7.1 10.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Nop14 PF04147.7 ETO34945.1 - 6.8 4.4 28.4 10 3.8 19.7 1.3 1 0 0 1 1 1 0 Nop14-like family SUFU_C PF12470.3 ETO34945.1 - 9.2 5.7 8.4 16 5.0 5.9 1.4 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain Spc7 PF08317.6 ETO34946.1 - 0.13 10.9 34.1 0.0054 15.4 10.0 2.5 1 1 0 2 2 2 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.6 ETO34946.1 - 2.3 8.6 21.8 3.1 8.2 3.4 3.9 4 1 1 5 5 5 0 Syntaxin 6, N-terminal UBA PF00627.26 ETO34949.1 - 3.8e-15 55.2 2.4 4.9e-07 29.4 0.1 3.4 3 1 0 3 3 3 2 UBA/TS-N domain UBA_4 PF14555.1 ETO34949.1 - 0.0018 17.7 0.2 0.015 14.7 0.0 2.5 3 0 0 3 3 3 1 UBA-like domain Nucleo_P87 PF07267.6 ETO34949.1 - 0.0049 15.6 9.5 0.0063 15.2 6.6 1.0 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 FlxA PF14282.1 ETO34949.1 - 0.11 12.4 12.7 0.29 11.0 8.8 1.6 1 0 0 1 1 1 0 FlxA-like protein PhoU PF01895.14 ETO34949.1 - 0.14 12.5 9.7 2.7 8.5 0.6 3.5 2 1 1 3 3 3 0 PhoU domain TetR_C PF02909.12 ETO34949.1 - 0.18 11.4 2.6 0.34 10.5 0.1 2.6 1 1 2 3 3 3 0 Tetracyclin repressor, C-terminal all-alpha domain GAGA_bind PF06217.7 ETO34949.1 - 1.5 8.7 11.6 1.8 8.4 8.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF1510 PF07423.6 ETO34949.1 - 1.9 7.8 17.8 3 7.1 12.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) LTXXQ PF07813.7 ETO34949.1 - 2 8.9 14.9 0.79 10.2 4.6 2.4 2 0 0 2 2 2 0 LTXXQ motif family protein Spore_coat_CotO PF14153.1 ETO34949.1 - 2.8 7.3 17.7 6.4 6.1 12.3 1.6 1 0 0 1 1 1 0 Spore coat protein CotO RR_TM4-6 PF06459.7 ETO34949.1 - 4.1 7.2 15.8 5.3 6.8 11.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Atrophin-1 PF03154.10 ETO34949.1 - 6 4.8 13.7 7.9 4.4 9.5 1.1 1 0 0 1 1 1 0 Atrophin-1 family Rtf2 PF04641.7 ETO34949.1 - 9.7 5.3 19.5 12 4.9 13.2 1.4 1 1 0 1 1 1 0 Rtf2 RING-finger WD40 PF00400.27 ETO34951.1 - 5.5e-45 149.6 6.0 2.4e-12 46.2 0.1 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat DPPIV_N PF00930.16 ETO34951.1 - 0.00092 17.8 0.3 0.9 8.0 0.0 2.7 1 1 2 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Cytochrom_D1 PF02239.11 ETO34951.1 - 0.0025 16.1 1.3 0.64 8.2 0.1 2.4 1 1 0 2 2 2 2 Cytochrome D1 heme domain CppA_C PF14507.1 ETO34951.1 - 0.0093 16.1 0.1 0.047 13.8 0.0 2.1 2 0 0 2 2 2 1 CppA C-terminal Gmad1 PF10647.4 ETO34951.1 - 0.022 14.1 0.7 0.052 12.9 0.5 1.7 1 1 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain Nucleoporin_N PF08801.6 ETO34951.1 - 0.028 13.1 5.5 1.8 7.2 0.5 3.0 1 1 3 4 4 4 0 Nup133 N terminal like PQQ_2 PF13360.1 ETO34951.1 - 0.032 13.6 1.4 0.68 9.3 0.2 2.4 1 1 1 2 2 2 0 PQQ-like domain Resistin PF06954.6 ETO34951.1 - 0.074 13.3 0.1 3.6 7.9 0.0 2.9 1 1 2 3 3 3 0 Resistin RhoGEF PF00621.15 ETO34952.1 - 4.2e-08 33.2 4.3 5.6e-05 23.0 0.1 2.4 1 1 1 2 2 2 2 RhoGEF domain Borrelia_P83 PF05262.6 ETO34952.1 - 0.00021 19.7 10.7 0.00024 19.5 7.4 1.2 1 0 0 1 1 1 1 Borrelia P83/100 protein DDHD PF02862.12 ETO34952.1 - 0.81 9.4 8.2 1.1 9.0 5.7 1.2 1 0 0 1 1 1 0 DDHD domain GBP_C PF02841.9 ETO34952.1 - 1.1 8.3 13.1 1.2 8.2 9.1 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain CAF-1_p150 PF11600.3 ETO34952.1 - 1.7 7.9 27.4 2.2 7.5 19.0 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Macoilin PF09726.4 ETO34952.1 - 2 6.6 12.3 2.1 6.5 8.6 1.0 1 0 0 1 1 1 0 Transmembrane protein TEX19 PF15553.1 ETO34952.1 - 2.3 8.0 5.5 3.8 7.3 3.8 1.4 1 0 0 1 1 1 0 Testis-expressed protein 19 CDC45 PF02724.9 ETO34952.1 - 3.4 5.5 13.5 4.4 5.2 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Spore_coat_CotO PF14153.1 ETO34952.1 - 3.5 7.0 17.4 5 6.5 12.1 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Kelch_6 PF13964.1 ETO34953.1 - 1.5e-07 31.2 3.1 0.11 12.6 0.0 4.2 3 1 1 4 4 4 3 Kelch motif Kelch_1 PF01344.20 ETO34953.1 - 6.6e-07 28.7 2.8 0.00015 21.2 0.2 3.8 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 ETO34953.1 - 1.4e-05 24.9 1.6 0.082 12.8 0.5 4.0 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO34953.1 - 0.00052 19.7 0.4 0.55 10.0 0.1 3.0 1 1 1 2 2 2 2 Galactose oxidase, central domain WD40 PF00400.27 ETO34954.1 - 1.1e-83 272.4 14.8 5.2e-15 54.6 0.4 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO34954.1 - 1.5e-08 33.2 5.3 0.44 8.6 0.0 5.6 1 1 1 3 3 3 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO34954.1 - 1.9e-08 34.0 0.0 1.9e-06 27.4 0.0 2.2 1 1 1 2 2 2 1 PQQ-like domain Nucleoporin_N PF08801.6 ETO34954.1 - 1.1e-06 27.6 2.1 0.53 8.9 0.1 4.7 1 1 2 3 3 3 2 Nup133 N terminal like PD40 PF07676.7 ETO34954.1 - 2.9e-06 26.8 1.0 5.9 6.6 0.0 5.8 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 ETO34954.1 - 3.9e-05 22.8 2.1 2.2 7.3 0.0 4.5 1 1 4 5 5 5 1 Neuroblastoma-amplified sequence, N terminal DPPIV_N PF00930.16 ETO34954.1 - 4e-05 22.3 0.0 0.26 9.8 0.0 3.8 1 1 3 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region BBS2_Mid PF14783.1 ETO34954.1 - 0.00017 21.3 2.2 1.5 8.6 0.0 4.6 1 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region IKI3 PF04762.7 ETO34954.1 - 0.00026 18.9 0.0 0.00046 18.1 0.0 1.4 1 1 0 1 1 1 1 IKI3 family Hira PF07569.6 ETO34954.1 - 0.0048 16.1 0.1 6.4 5.9 0.0 4.1 2 2 2 5 5 5 1 TUP1-like enhancer of split DHFR_2 PF06442.6 ETO34954.1 - 0.012 15.2 0.0 1.3 8.7 0.0 3.1 4 0 0 4 4 4 0 R67 dihydrofolate reductase DUF4221 PF13970.1 ETO34954.1 - 0.017 14.4 0.1 1.9 7.6 0.0 3.4 2 2 2 4 4 4 0 Domain of unknown function (DUF4221) Pectate_lyase22 PF14583.1 ETO34954.1 - 0.021 13.3 0.0 0.048 12.1 0.0 1.6 1 0 0 1 1 1 0 Oligogalacturonate lyase Proteasome_A_N PF10584.4 ETO34954.1 - 0.023 13.9 1.3 35 3.8 0.0 4.5 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature RicinB_lectin_2 PF14200.1 ETO34954.1 - 0.035 14.4 0.8 0.34 11.3 0.0 2.6 2 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Resistin PF06954.6 ETO34954.1 - 0.035 14.3 0.3 59 4.0 0.0 4.0 2 2 2 4 4 4 0 Resistin DUF1258 PF06869.7 ETO34954.1 - 0.035 13.1 1.1 0.61 9.1 0.1 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1258) DUF1797 PF08796.5 ETO34954.1 - 0.042 13.7 0.0 8.2 6.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1797) DUF3261 PF11659.3 ETO34954.1 - 0.078 12.5 0.0 7.1 6.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3261) RGS PF00615.14 ETO34955.1 - 0.016 15.3 0.4 0.026 14.6 0.3 1.3 1 0 0 1 1 1 0 Regulator of G protein signaling domain WD40 PF00400.27 ETO34956.1 - 3.8e-12 45.5 1.3 9.6e-12 44.3 0.1 2.1 3 0 0 3 3 3 1 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO34956.1 - 0.023 13.4 0.1 0.024 13.3 0.0 1.1 1 0 0 1 1 1 0 Nup133 N terminal like UpxZ PF06603.6 ETO34956.1 - 0.038 13.9 0.0 0.05 13.6 0.0 1.2 1 0 0 1 1 1 0 UpxZ family of transcription anti-terminator antagonists SAM_1 PF00536.25 ETO34957.1 - 1.5e-06 28.2 0.0 3e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO34957.1 - 4.3e-06 26.4 0.0 9.4e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ PF00595.19 ETO34957.1 - 0.00017 21.6 0.1 0.00052 20.1 0.0 1.9 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 ETO34957.1 - 0.00034 20.4 1.5 0.0013 18.5 0.0 2.6 3 1 0 3 3 3 1 PDZ domain PIG-S PF10510.4 ETO34957.1 - 0.21 10.2 5.0 0.17 10.5 0.3 2.0 2 0 0 2 2 2 0 Phosphatidylinositol-glycan biosynthesis class S protein EndoU_bacteria PF14436.1 ETO34957.1 - 1.2 9.0 5.0 15 5.4 1.0 2.4 2 1 0 2 2 2 0 Bacterial EndoU nuclease Med19 PF10278.4 ETO34957.1 - 5 6.7 10.1 0.29 10.7 3.4 1.5 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Nucleoplasmin PF03066.10 ETO34957.1 - 8.4 5.9 11.7 0.72 9.3 0.2 2.4 2 0 0 2 2 2 0 Nucleoplasmin Prothymosin PF03247.9 ETO34958.1 - 0.0096 16.0 21.1 0.015 15.4 14.6 1.2 1 0 0 1 1 1 1 Prothymosin/parathymosin family Daxx PF03344.10 ETO34958.1 - 0.12 10.8 17.0 0.16 10.3 11.8 1.1 1 0 0 1 1 1 0 Daxx Family Nucleo_P87 PF07267.6 ETO34958.1 - 0.18 10.4 2.8 0.19 10.3 1.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF2457 PF10446.4 ETO34958.1 - 0.26 9.9 13.1 0.35 9.5 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 ETO34958.1 - 0.39 8.6 13.3 0.5 8.3 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 ETO34958.1 - 0.42 8.4 12.9 0.51 8.1 9.0 1.1 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.6 ETO34958.1 - 0.7 9.3 12.9 0.94 8.9 9.0 1.2 1 0 0 1 1 1 0 PPP4R2 DDHD PF02862.12 ETO34958.1 - 0.71 9.6 6.5 1 9.1 4.5 1.2 1 0 0 1 1 1 0 DDHD domain FLO_LFY PF01698.11 ETO34958.1 - 1.3 7.7 6.8 1.7 7.4 4.7 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein NOA36 PF06524.7 ETO34958.1 - 2.1 7.5 9.5 2.7 7.1 6.6 1.2 1 0 0 1 1 1 0 NOA36 protein DUF2201_N PF13203.1 ETO34958.1 - 3.2 6.8 8.9 4.3 6.4 6.1 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Trypan_PARP PF05887.6 ETO34958.1 - 3.5 7.4 13.7 5.4 6.8 9.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pox_Ag35 PF03286.9 ETO34958.1 - 4.9 6.6 11.9 7.4 6.0 8.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM176 PF14851.1 ETO34958.1 - 5.7 6.5 10.8 1.8e+02 1.7 0.0 2.4 2 1 0 2 2 2 0 FAM176 family Paf1 PF03985.8 ETO34958.1 - 7.2 5.2 18.0 9.7 4.8 12.5 1.1 1 0 0 1 1 1 0 Paf1 CobT PF06213.7 ETO34958.1 - 9.2 5.3 18.2 12 4.8 12.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT WD40 PF00400.27 ETO34959.1 - 1.8e-131 423.8 16.6 1.3e-12 47.1 0.0 12.1 12 0 0 12 12 12 12 WD domain, G-beta repeat Nup160 PF11715.3 ETO34959.1 - 1.2e-17 63.3 17.7 0.016 13.3 0.1 9.4 1 1 6 8 8 8 7 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO34959.1 - 3e-08 33.4 0.9 3.3e-05 23.4 0.0 2.8 1 1 1 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 ETO34959.1 - 1.4e-07 30.6 19.4 0.023 13.4 0.5 6.8 2 2 3 7 7 7 3 Nup133 N terminal like DPPIV_N PF00930.16 ETO34959.1 - 1.4e-07 30.4 0.1 0.13 10.8 0.0 6.2 2 1 5 7 7 7 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Str_synth PF03088.11 ETO34959.1 - 1.8e-06 27.9 0.1 30 4.7 0.0 7.4 7 2 1 9 9 9 0 Strictosidine synthase PD40 PF07676.7 ETO34959.1 - 2e-05 24.1 18.3 6.6 6.5 0.1 8.7 9 0 0 9 9 9 2 WD40-like Beta Propeller Repeat F420_ligase PF01996.11 ETO34959.1 - 4.4e-05 22.6 0.0 4.8 6.1 0.0 4.2 4 0 0 4 4 4 2 F420-0:Gamma-glutamyl ligase Cytochrom_D1 PF02239.11 ETO34959.1 - 0.00049 18.5 3.8 0.36 9.0 0.2 4.7 1 1 5 7 7 7 2 Cytochrome D1 heme domain DUF4072 PF13284.1 ETO34959.1 - 0.00081 19.5 0.0 17 5.6 0.0 6.3 9 0 0 9 9 9 0 Domain of unknown function (DUF4072) DUF1258 PF06869.7 ETO34959.1 - 0.0014 17.8 1.1 2 7.4 0.0 4.6 2 1 2 6 6 6 1 Protein of unknown function (DUF1258) Pectate_lyase22 PF14583.1 ETO34959.1 - 0.0031 16.0 0.0 0.77 8.1 0.0 3.2 2 2 3 5 5 5 1 Oligogalacturonate lyase CPSF_A PF03178.10 ETO34959.1 - 0.017 14.2 0.0 0.061 12.4 0.0 1.9 2 0 0 2 2 2 0 CPSF A subunit region PPR_2 PF13041.1 ETO34961.1 - 6.6e-13 48.4 8.8 1.4e-08 34.6 0.3 4.2 3 1 1 4 4 4 3 PPR repeat family PPR PF01535.15 ETO34961.1 - 7e-13 47.6 2.9 0.011 15.6 0.0 4.9 4 0 0 4 4 4 4 PPR repeat PPR_3 PF13812.1 ETO34961.1 - 5.4e-08 32.5 0.1 0.21 11.9 0.0 4.5 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 ETO34961.1 - 9.2e-07 28.2 1.1 0.037 13.4 0.0 3.5 3 0 0 3 3 3 3 PPR repeat DUF2419 PF10343.4 ETO34962.1 - 7.5e-09 35.2 1.1 7.5e-09 35.2 0.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2419) DRMBL PF07522.9 ETO34962.1 - 0.0013 18.8 0.0 0.0053 16.7 0.0 2.1 1 1 1 2 2 2 1 DNA repair metallo-beta-lactamase SH2_2 PF14633.1 ETO34963.1 - 8.4e-35 119.8 0.7 4.7e-34 117.3 0.5 1.8 1 1 0 1 1 1 1 SH2 domain SH2 PF00017.19 ETO34963.1 - 0.0095 15.7 0.0 0.078 12.7 0.0 2.2 2 0 0 2 2 2 1 SH2 domain XRCC4 PF06632.7 ETO34963.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF3647 PF12363.3 ETO34963.1 - 0.2 11.7 1.2 14 5.8 0.0 2.8 3 0 0 3 3 3 0 Phage protein DLD PF14878.1 ETO34964.1 - 6.5e-11 42.3 0.4 3.4e-10 40.0 0.1 2.0 2 0 0 2 2 2 1 Death-like domain of SPT6 S1 PF00575.18 ETO34964.1 - 0.00017 21.5 0.0 0.0004 20.4 0.0 1.7 1 1 0 1 1 1 1 S1 RNA binding domain Phospholip_A2_2 PF05826.7 ETO34964.1 - 0.086 12.8 4.9 5.1 7.0 2.9 2.2 2 0 0 2 2 2 0 Phospholipase A2 Myosin_N PF02736.14 ETO34964.1 - 0.11 12.1 0.0 0.84 9.3 0.0 2.5 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain WD40 PF00400.27 ETO34966.1 - 3.6e-26 90.0 0.3 4.6e-12 45.3 0.0 3.1 2 0 0 2 2 2 2 WD domain, G-beta repeat Kelch_1 PF01344.20 ETO34966.1 - 5.9e-09 35.3 6.4 6e-07 28.9 0.3 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO34966.1 - 2.8e-08 33.5 9.9 0.0079 16.3 0.2 4.1 3 1 1 4 4 4 3 Kelch motif Kelch_5 PF13854.1 ETO34966.1 - 1.3e-06 28.1 9.4 0.17 11.8 0.1 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.1 ETO34966.1 - 4.1e-05 23.2 0.1 0.28 10.9 0.0 2.8 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO34966.1 - 0.0011 19.1 0.0 0.024 14.7 0.0 2.9 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO34966.1 - 0.0042 16.7 2.2 0.73 9.7 0.0 3.9 4 0 0 4 4 4 1 Kelch motif WIYLD PF10440.4 ETO34967.1 - 0.084 12.8 0.1 0.22 11.4 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin-binding WIYLD domain YWFCY PF14293.1 ETO34967.1 - 1 9.2 5.7 0.64 9.9 1.1 2.2 2 0 0 2 2 2 0 YWFCY protein PUF PF00806.14 ETO34968.1 - 1.4e-41 137.6 14.2 2.1e-06 26.9 0.1 7.8 8 0 0 8 8 8 6 Pumilio-family RNA binding repeat DUF4350 PF14258.1 ETO34968.1 - 0.12 12.5 0.0 40 4.5 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4350) Peroxidase_2 PF01328.12 ETO34968.1 - 0.2 10.3 0.2 0.34 9.5 0.1 1.3 1 0 0 1 1 1 0 Peroxidase, family 2 WD40 PF00400.27 ETO34969.1 - 3e-34 115.6 8.4 1.5e-06 27.8 0.0 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 ETO34969.1 - 1.4e-05 24.8 1.1 0.14 11.8 0.2 2.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO34969.1 - 0.00033 18.9 8.2 0.032 12.3 0.0 2.9 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO34969.1 - 0.00047 18.5 0.5 0.019 13.3 0.1 2.0 2 0 0 2 2 2 2 Cytochrome D1 heme domain ACI44 PF15270.1 ETO34969.1 - 0.023 14.6 0.2 2.1 8.3 0.0 2.5 2 0 0 2 2 2 0 Metallo-carboxypeptidase inhibitor Cor1 PF04803.7 ETO34969.1 - 0.073 12.8 0.3 0.5 10.1 0.1 2.0 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region BBS2_Mid PF14783.1 ETO34969.1 - 0.25 11.1 3.9 18 5.1 0.0 4.0 2 2 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region RhoGAP PF00620.22 ETO34970.1 - 0.048 13.2 0.1 0.083 12.4 0.1 1.4 1 0 0 1 1 1 0 RhoGAP domain WD40 PF00400.27 ETO34971.1 - 2.5e-63 207.8 24.8 1e-10 41.0 0.7 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO34971.1 - 1.1e-15 56.8 3.6 0.0001 20.6 0.0 5.0 1 1 4 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO34971.1 - 7.1e-06 25.0 9.6 0.014 14.1 2.0 4.1 1 1 2 3 3 3 3 Nup133 N terminal like HAD PF12710.2 ETO34971.1 - 0.61 10.2 3.7 96 3.0 2.6 3.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF998 PF06197.8 ETO34972.1 - 0.00014 21.2 12.6 0.036 13.3 0.0 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF998) DUF4225 PF13988.1 ETO34972.1 - 0.2 11.0 2.8 1.6 8.1 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4225) DctQ PF04290.7 ETO34972.1 - 7.1 6.4 15.5 2.3 8.0 2.8 3.0 2 1 1 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component HTH_23 PF13384.1 ETO34973.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain Terminase_5 PF06056.7 ETO34973.1 - 0.11 12.0 0.2 0.21 11.1 0.1 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) MKT1_C PF12246.3 ETO34974.1 - 0.1 11.5 4.6 0.12 11.3 3.2 1.2 1 0 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication alpha-hel2 PF14456.1 ETO34974.1 - 0.14 10.8 5.2 0.16 10.7 3.6 1.0 1 0 0 1 1 1 0 Alpha-helical domain 2 RNase_H2_suC PF08615.6 ETO34974.1 - 0.19 11.5 9.5 0.24 11.2 6.6 1.1 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) SeqA PF03925.8 ETO34974.1 - 0.49 10.0 6.9 0.59 9.8 4.8 1.0 1 0 0 1 1 1 0 SeqA protein Spt5_N PF11942.3 ETO34974.1 - 0.5 11.0 15.0 0.66 10.6 10.4 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Sigma70_ner PF04546.8 ETO34974.1 - 0.55 9.8 17.7 0.89 9.1 12.2 1.4 1 1 0 1 1 1 0 Sigma-70, non-essential region Trypan_glycop_C PF10659.4 ETO34974.1 - 1.1 9.5 14.4 1.2 9.4 10.0 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain DUF4484 PF14831.1 ETO34974.1 - 1.2 9.1 8.8 1.9 8.5 6.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4484) Laps PF10169.4 ETO34974.1 - 1.8 8.7 17.8 2.1 8.5 12.4 1.1 1 0 0 1 1 1 0 Learning-associated protein FAM176 PF14851.1 ETO34974.1 - 2.3 7.9 10.4 2.4 7.8 7.2 1.2 1 0 0 1 1 1 0 FAM176 family SMN PF06003.7 ETO34974.1 - 3.2 6.7 7.4 3.2 6.7 5.1 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DNA_pol_phi PF04931.8 ETO34974.1 - 4.2 5.0 16.1 4 5.0 11.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Pox_RNA_Pol_19 PF05320.7 ETO34974.1 - 4.5 7.0 14.6 5.2 6.7 10.1 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit BSP_II PF05432.6 ETO34974.1 - 4.7 6.4 16.2 4.3 6.5 11.3 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF1943 PF09172.6 ETO34974.1 - 6.8 5.4 7.7 7 5.4 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) zf-LITAF-like PF10601.4 ETO34975.1 - 0.065 13.1 0.2 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain Vps51 PF08700.6 ETO34976.1 - 0.0046 16.7 0.9 0.0046 16.7 0.7 2.4 2 1 0 2 2 2 1 Vps51/Vps67 COG5 PF10392.4 ETO34976.1 - 0.034 14.0 1.8 0.034 14.0 1.2 3.3 2 2 1 3 3 3 0 Golgi transport complex subunit 5 DUF4211 PF13926.1 ETO34977.1 - 0.084 12.2 0.8 0.12 11.8 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4211) Rsm22 PF09243.5 ETO34978.1 - 1.6e-21 76.5 0.1 2.7e-17 62.6 0.0 3.1 2 1 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 PAP_RNA-bind PF04926.10 ETO34979.1 - 0.012 15.1 1.4 0.016 14.7 0.7 1.5 1 1 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain PH PF00169.24 ETO34984.1 - 1.3e-15 57.4 1.1 1.3e-15 57.4 0.8 2.1 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 ETO34984.1 - 4.2e-10 39.8 6.1 2.6e-08 34.1 1.7 3.3 2 1 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 ETO34984.1 - 6.1e-08 32.6 0.3 1.4e-07 31.4 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3115 PF11312.3 ETO34985.1 - 0.073 11.9 0.0 0.081 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3115) Cyto_ox_2 PF02322.10 ETO34986.1 - 0.019 14.1 1.2 0.024 13.7 0.8 1.1 1 0 0 1 1 1 0 Cytochrome oxidase subunit II TetR_N PF00440.18 ETO34988.1 - 0.025 14.1 0.1 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family PUB PF09409.5 ETO34988.1 - 0.026 14.2 2.3 0.033 13.9 0.4 2.1 3 0 0 3 3 3 0 PUB domain HSDR_N_2 PF13588.1 ETO34989.1 - 0.076 12.8 0.2 0.096 12.4 0.1 1.3 1 1 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) WD40 PF00400.27 ETO34990.1 - 2.5e-41 138.1 13.8 2.1e-11 43.2 0.0 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO34990.1 - 1.8e-10 39.6 1.8 0.00024 19.3 0.5 3.1 1 1 1 3 3 3 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO34990.1 - 0.00057 19.6 0.0 0.079 12.7 0.0 2.2 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region DUF4221 PF13970.1 ETO34990.1 - 0.11 11.7 1.9 0.45 9.7 1.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4221) Sulfatase PF00884.18 ETO34991.1 - 2.7e-05 23.5 0.0 3.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Sulfatase COesterase PF00135.23 ETO34992.1 - 7.6e-43 147.0 0.5 1.1e-42 146.4 0.4 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETO34992.1 - 0.01 15.4 0.4 0.02 14.5 0.3 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold FlaC_arch PF05377.6 ETO34992.1 - 0.14 12.0 1.8 2.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Ras PF00071.17 ETO34994.1 - 0.00031 20.1 0.1 0.0019 17.6 0.0 2.1 2 0 0 2 2 2 1 Ras family PH PF00169.24 ETO34994.1 - 0.0069 16.5 3.8 0.021 15.0 0.1 3.3 3 0 0 3 3 3 1 PH domain PH_11 PF15413.1 ETO34994.1 - 0.079 13.2 3.2 0.11 12.7 0.0 2.9 4 0 0 4 4 4 0 Pleckstrin homology domain Voltage_CLC PF00654.15 ETO34995.1 - 3.4e-55 187.4 11.1 4.9e-55 186.9 7.7 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 ETO34995.1 - 8.7e-10 38.2 0.0 0.0003 20.5 0.0 2.5 2 0 0 2 2 2 2 CBS domain Voltage_CLC PF00654.15 ETO34996.1 - 3.8e-26 91.9 6.2 5.1e-26 91.5 3.1 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel Exo_endo_phos_2 PF14529.1 ETO34998.1 - 3e-14 52.6 0.8 4.8e-14 52.0 0.5 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF2051 PF09738.4 ETO34998.1 - 0.005 16.1 4.0 0.0068 15.7 2.8 1.3 1 0 0 1 1 1 1 Double stranded RNA binding protein (DUF2051) Nanovirus_C8 PF05629.6 ETO34998.1 - 0.047 13.4 0.2 0.32 10.7 0.0 2.1 1 1 1 2 2 2 0 Nanovirus component 8 (C8) protein WD40 PF00400.27 ETO34999.1 - 4.3e-54 178.5 12.1 4.1e-10 39.1 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO34999.1 - 2.4e-11 43.7 0.6 0.013 15.2 0.0 3.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO34999.1 - 9.4e-07 28.3 2.4 0.19 11.4 0.0 4.6 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO34999.1 - 2.3e-05 24.0 0.4 6.8e-05 22.4 0.3 1.9 1 1 0 1 1 1 1 PQQ-like domain Nup160 PF11715.3 ETO34999.1 - 0.0043 15.2 2.0 1.4 6.9 0.1 3.6 1 1 1 3 3 3 2 Nucleoporin Nup120/160 GspH PF12019.3 ETO34999.1 - 0.015 15.4 1.8 0.73 9.9 0.0 3.0 3 1 0 3 3 3 0 Type II transport protein GspH Cytochrom_D1 PF02239.11 ETO34999.1 - 0.032 12.5 0.4 2.8 6.1 0.0 2.7 1 1 2 3 3 3 0 Cytochrome D1 heme domain Pik1 PF11522.3 ETO35000.1 - 0.0003 20.4 0.3 0.0017 18.0 0.1 2.3 2 0 0 2 2 2 1 Yeast phosphatidylinositol-4-OH kinase Pik1 EIF_2_alpha PF07541.7 ETO35001.1 - 0.013 15.2 0.1 0.02 14.6 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit DUF4277 PF14104.1 ETO35001.1 - 0.029 14.5 0.1 0.062 13.4 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4277) HCNGP PF07818.8 ETO35001.1 - 0.11 12.5 3.3 0.24 11.4 1.2 2.1 2 0 0 2 2 2 0 HCNGP-like protein WD40 PF00400.27 ETO35002.1 - 8.1e-06 25.5 0.6 0.00096 18.9 0.5 2.9 2 1 0 2 2 2 1 WD domain, G-beta repeat AvrB_AvrC PF05394.6 ETO35002.1 - 0.048 12.6 0.1 0.052 12.5 0.1 1.1 1 0 0 1 1 1 0 Avirulence protein WD40 PF00400.27 ETO35003.1 - 6.6e-34 114.5 11.0 4.6e-13 48.5 0.2 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO35003.1 - 4.4e-06 25.1 0.1 0.0038 15.4 0.0 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO35003.1 - 0.0087 15.9 0.1 0.1 12.5 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3601) BBS2_N PF14781.1 ETO35003.1 - 0.066 12.8 0.6 0.27 10.8 0.3 2.1 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal Kelch_6 PF13964.1 ETO35003.1 - 0.069 13.3 2.8 10 6.4 0.1 3.2 2 1 1 3 3 3 0 Kelch motif Inositol_P PF00459.20 ETO35005.1 - 6.8e-13 48.5 0.1 8.1e-09 35.1 0.0 2.3 2 1 1 3 3 3 2 Inositol monophosphatase family Sugar_tr PF00083.19 ETO35005.1 - 0.16 10.5 0.0 0.22 10.0 0.0 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter WD40 PF00400.27 ETO35006.1 - 2e-56 185.9 28.0 3.4e-11 42.5 0.1 7.6 6 1 1 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO35006.1 - 8.6e-10 37.3 1.2 0.0021 16.2 0.0 4.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO35006.1 - 1.3e-06 28.6 2.8 5e-06 26.7 2.0 2.0 1 0 0 1 1 1 1 TRAF-type zinc finger PQQ_2 PF13360.1 ETO35006.1 - 0.031 13.7 0.6 0.24 10.8 0.4 1.9 1 1 0 2 2 2 0 PQQ-like domain PQQ_3 PF13570.1 ETO35006.1 - 0.12 12.6 0.5 7 7.0 0.0 3.4 2 1 2 4 4 4 0 PQQ-like domain SprB PF13573.1 ETO35006.1 - 0.73 9.4 12.4 0.97 9.0 0.1 3.7 3 0 0 3 3 3 0 SprB repeat POP1 PF06978.6 ETO35007.1 - 0.031 13.9 3.6 0.056 13.1 2.4 1.5 1 1 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 DCA16 PF15349.1 ETO35007.1 - 0.1 11.9 0.9 0.16 11.2 0.6 1.3 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 eIF3_subunit PF08597.5 ETO35007.1 - 1.1 8.8 13.3 0.68 9.4 1.5 2.4 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit WD40 PF00400.27 ETO35008.1 - 1.9e-52 173.3 24.9 3.9e-11 42.3 1.6 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO35008.1 - 9.4e-13 47.1 1.2 0.0023 16.1 0.0 5.0 3 2 1 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO35008.1 - 0.0044 15.8 13.0 0.082 11.6 0.0 4.0 2 1 1 4 4 4 2 Nup133 N terminal like DUF4178 PF13785.1 ETO35008.1 - 0.025 14.5 0.0 13 5.7 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4178) DUF2559 PF10832.3 ETO35008.1 - 0.48 10.2 2.9 19 5.1 0.0 3.3 5 0 0 5 5 5 0 Protein of unknown function (DUF2559) WD40 PF00400.27 ETO35009.1 - 1.1e-63 208.9 25.0 3.5e-11 42.5 0.6 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO35009.1 - 3e-13 48.7 4.4 0.002 16.3 0.1 5.9 2 2 4 6 6 6 6 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO35009.1 - 0.0011 18.6 0.6 0.51 10.1 0.0 4.0 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.1 ETO35009.1 - 0.069 12.6 1.3 5.9 6.2 0.0 2.5 2 1 0 2 2 2 0 PQQ-like domain WD40 PF00400.27 ETO35010.1 - 1.5e-52 173.6 33.5 1.1e-11 44.1 0.0 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat zf-TRAF PF02176.13 ETO35010.1 - 0.00028 21.1 3.2 0.0011 19.2 2.2 2.1 1 0 0 1 1 1 1 TRAF-type zinc finger Wzy_C PF04932.10 ETO35010.1 - 0.58 9.9 2.8 1.6 8.4 0.1 2.3 2 0 0 2 2 2 0 O-Antigen ligase DUF1777 PF08648.7 ETO35011.1 - 0.034 13.8 98.2 0.72 9.5 31.9 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1777) HEAT PF02985.17 ETO35013.1 - 1.6e-12 46.3 0.6 0.0097 15.9 0.0 7.0 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.1 ETO35013.1 - 3.3e-11 43.3 0.0 0.00093 19.4 0.0 4.1 3 1 1 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 ETO35013.1 - 6e-06 26.5 0.0 0.11 13.0 0.0 4.1 3 1 1 4 4 4 2 HEAT-like repeat Activator-TraM PF11657.3 ETO35013.1 - 0.00021 20.8 0.2 0.00058 19.3 0.1 1.7 1 0 0 1 1 1 1 Transcriptional activator TraM Cnd1 PF12717.2 ETO35013.1 - 0.0049 16.7 14.8 0.082 12.7 0.1 3.7 1 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 MOR2-PAG1_C PF14225.1 ETO35013.1 - 0.026 14.2 2.3 1.8 8.2 0.1 3.1 2 1 0 2 2 2 0 Cell morphogenesis C-terminal NLE PF08154.7 ETO35013.1 - 0.085 12.8 6.6 15 5.7 0.1 5.5 4 1 2 6 6 6 0 NLE (NUC135) domain SFTA2 PF15210.1 ETO35013.1 - 0.89 9.1 3.2 0.56 9.8 0.4 2.0 2 0 0 2 2 2 0 Surfactant-associated protein 2 Condensin2nSMC PF12422.3 ETO35013.1 - 1.1 9.0 6.1 8.1 6.1 0.5 3.4 3 1 1 4 4 4 0 Condensin II non structural maintenance of chromosomes subunit HSP70 PF00012.15 ETO35013.1 - 1.4 6.7 6.8 0.31 8.9 0.5 2.6 2 1 1 3 3 3 0 Hsp70 protein WD40 PF00400.27 ETO35016.1 - 8.4e-176 564.4 54.3 1.5e-13 50.0 0.1 14.2 14 0 0 14 14 14 14 WD domain, G-beta repeat PQQ_2 PF13360.1 ETO35016.1 - 5.6e-19 68.5 7.1 9.5e-05 21.9 0.2 5.7 1 1 4 6 6 6 6 PQQ-like domain Nup160 PF11715.3 ETO35016.1 - 4.6e-14 51.4 16.2 0.15 10.1 0.0 9.7 1 1 4 8 8 8 7 Nucleoporin Nup120/160 PD40 PF07676.7 ETO35016.1 - 3.9e-12 45.5 26.1 8.2 6.2 0.0 13.0 13 0 0 13 13 13 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO35016.1 - 5e-08 31.6 3.0 0.27 9.4 0.0 5.7 2 1 2 6 6 6 2 Cytochrome D1 heme domain DUF1258 PF06869.7 ETO35016.1 - 3.9e-07 29.4 0.9 0.026 13.5 0.0 4.9 3 2 1 5 5 5 2 Protein of unknown function (DUF1258) DUF727 PF05303.7 ETO35016.1 - 3.1e-06 26.9 0.6 6.9 6.5 0.0 8.2 7 4 3 11 11 11 1 Protein of unknown function (DUF727) Gmad1 PF10647.4 ETO35016.1 - 4e-06 26.4 0.0 1.9 7.7 0.0 6.0 1 1 2 4 4 4 1 Lipoprotein LpqB beta-propeller domain NYD-SP28_assoc PF14775.1 ETO35016.1 - 2.7e-05 23.7 7.3 9.7 5.9 0.0 8.7 10 0 0 10 10 10 0 Sperm tail C-terminal domain TolB_N PF04052.8 ETO35016.1 - 0.00024 21.1 0.2 28 4.8 0.0 7.5 9 0 0 9 9 9 0 TolB amino-terminal domain Pentapeptide_4 PF13599.1 ETO35016.1 - 0.00025 20.7 0.0 0.00058 19.6 0.0 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETO35016.1 - 0.00027 20.0 0.3 0.00053 19.1 0.2 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Mid2 PF04478.7 ETO35016.1 - 0.00031 20.1 2.7 0.62 9.4 0.0 5.1 6 2 2 8 8 8 1 Mid2 like cell wall stress sensor DUF1652 PF07865.6 ETO35016.1 - 0.00099 18.6 0.1 22 4.7 0.0 7.2 12 0 0 12 12 11 0 Protein of unknown function (DUF1652) Pentapeptide_3 PF13576.1 ETO35016.1 - 0.0017 18.2 0.4 0.0047 16.7 0.2 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) DUF3312 PF11768.3 ETO35016.1 - 0.0017 16.6 0.0 10 4.1 0.0 5.1 6 1 2 8 8 8 0 Protein of unknown function (DUF3312) Proteasome_A_N PF10584.4 ETO35016.1 - 0.016 14.5 37.4 22 4.4 0.0 12.3 13 0 0 13 13 13 0 Proteasome subunit A N-terminal signature dsrm PF00035.20 ETO35016.1 - 0.02 15.4 3.7 1.5e+02 3.0 0.0 6.8 9 1 1 10 10 6 0 Double-stranded RNA binding motif CPSF_A PF03178.10 ETO35016.1 - 0.088 11.8 0.0 17 4.3 0.0 3.0 3 0 0 3 3 3 0 CPSF A subunit region WD40 PF00400.27 ETO35017.1 - 2.2e-17 62.1 1.0 6.5e-10 38.5 0.0 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO35017.1 - 0.0002 19.6 0.6 0.13 10.3 0.1 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO35017.1 - 0.0035 16.1 2.1 0.81 8.3 0.2 2.2 1 1 0 2 2 2 2 Nup133 N terminal like Phage_antitermQ PF06530.7 ETO35017.1 - 0.074 12.6 0.2 0.21 11.1 0.1 1.8 1 1 1 2 2 2 0 Phage antitermination protein Q DUF1914 PF08932.5 ETO35017.1 - 1.1 9.2 5.4 2.3 8.2 0.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1914) WD40 PF00400.27 ETO35018.1 - 8.4e-62 203.0 22.1 1e-10 41.0 0.5 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO35018.1 - 6.8e-19 67.4 2.1 0.00025 19.3 0.3 6.0 1 1 5 6 6 6 6 Nucleoporin Nup120/160 DUF851 PF05867.6 ETO35018.1 - 4.6e-05 22.7 0.1 0.19 10.9 0.0 3.3 3 1 1 4 4 4 2 Protein of unknown function (DUF851) DUF1900 PF08954.6 ETO35018.1 - 9.5e-05 21.9 0.1 0.14 11.6 0.0 4.2 4 1 1 5 5 5 1 Domain of unknown function (DUF1900) PQQ_2 PF13360.1 ETO35018.1 - 0.0027 17.2 1.3 2.8 7.3 0.1 2.8 2 2 0 3 3 3 2 PQQ-like domain DUF3601 PF12208.3 ETO35018.1 - 0.014 15.2 0.1 2.5 8.0 0.0 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF3601) Methyltransf_25 PF13649.1 ETO35018.1 - 0.095 13.0 0.0 41 4.6 0.0 4.1 5 0 0 5 5 5 0 Methyltransferase domain PQQ_3 PF13570.1 ETO35018.1 - 0.13 12.5 1.6 61 4.0 0.0 4.4 6 0 0 6 6 6 0 PQQ-like domain DUF1914 PF08932.5 ETO35018.1 - 0.24 11.4 6.4 40 4.2 0.1 4.3 3 1 2 5 5 5 0 Domain of unknown function (DUF1914) 3Beta_HSD PF01073.14 ETO35019.1 - 0.0039 15.9 0.9 0.006 15.3 0.6 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family CMV_1a PF12467.3 ETO35020.1 - 0.37 11.1 4.5 0.54 10.6 3.1 1.3 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Enolase_C PF00113.17 ETO35021.1 - 1.1e-08 34.4 0.6 1.3e-08 34.2 0.4 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain GIDA PF01134.17 ETO35021.1 - 0.02 13.7 0.2 0.033 13.0 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A TrkH PF02386.11 ETO35022.1 - 0.0028 16.2 0.3 0.0037 15.9 0.2 1.2 1 0 0 1 1 1 1 Cation transport protein Enolase_N PF03952.11 ETO35022.1 - 0.0079 16.1 1.5 0.013 15.4 0.1 1.9 2 0 0 2 2 2 1 Enolase, N-terminal domain DUF912 PF06024.7 ETO35022.1 - 0.06 13.4 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2353 PF09789.4 ETO35023.1 - 0.0046 16.2 12.2 0.0046 16.2 8.5 2.6 2 1 1 3 3 3 1 Uncharacterized coiled-coil protein (DUF2353) PASTA PF03793.14 ETO35023.1 - 0.02 14.5 1.1 0.38 10.4 0.1 3.0 2 1 0 2 2 2 0 PASTA domain PA28_beta PF02252.13 ETO35023.1 - 0.029 13.8 5.3 0.044 13.2 1.6 2.5 2 0 0 2 2 2 0 Proteasome activator pa28 beta subunit His_Phos_1 PF00300.17 ETO35023.1 - 0.56 10.2 6.7 1.4 9.0 4.7 1.6 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) CENP-F_leu_zip PF10473.4 ETO35023.1 - 3.3 7.5 49.6 0.037 13.9 14.3 4.4 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HrpE PF06188.7 ETO35024.1 - 0.036 13.7 3.9 0.042 13.5 2.7 1.1 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E His_Phos_2 PF00328.17 ETO35024.1 - 0.1 11.8 1.4 0.11 11.8 1.0 1.1 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Peptidase_S46 PF10459.4 ETO35024.1 - 0.32 9.3 4.5 0.36 9.1 3.1 1.0 1 0 0 1 1 1 0 Peptidase S46 DNA_topoisoIV PF00521.15 ETO35024.1 - 0.47 9.2 6.9 0.51 9.1 4.8 1.0 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A MSG PF02349.10 ETO35024.1 - 0.66 9.9 11.5 1.1 9.2 7.9 1.5 1 0 0 1 1 1 0 Major surface glycoprotein Nop14 PF04147.7 ETO35025.1 - 1.9 6.3 36.6 2 6.2 25.4 1.0 1 0 0 1 1 1 0 Nop14-like family TPR_12 PF13424.1 ETO35027.1 - 7.1e-93 304.6 14.5 9.2e-26 89.6 0.0 5.7 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETO35027.1 - 6.6e-75 246.7 59.0 7.1e-16 57.6 2.5 6.4 2 1 6 8 8 8 7 TPR repeat TPR_10 PF13374.1 ETO35027.1 - 7.8e-60 197.2 0.0 2.4e-08 33.6 0.0 8.4 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_1 PF00515.23 ETO35027.1 - 1.8e-57 188.7 50.3 3e-10 39.2 1.6 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_7 PF13176.1 ETO35027.1 - 1.7e-54 177.3 1.6 7.3e-08 31.6 0.0 8.7 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_2 PF07719.12 ETO35027.1 - 7.5e-46 150.3 30.0 3e-07 29.8 0.4 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_8 PF13181.1 ETO35027.1 - 3.5e-39 129.6 60.4 7e-09 34.8 2.5 9.0 9 0 0 9 9 8 8 Tetratricopeptide repeat TPR_17 PF13431.1 ETO35027.1 - 1.1e-29 100.1 16.9 0.00033 20.6 0.0 9.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 ETO35027.1 - 2.8e-17 62.8 0.0 0.00047 20.7 0.0 6.4 3 2 5 9 9 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 ETO35027.1 - 3.1e-17 61.5 0.0 0.13 12.9 0.0 8.6 6 1 3 9 9 8 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO35027.1 - 1.3e-12 47.2 15.3 0.16 12.4 0.1 8.8 9 0 0 9 9 9 3 Tetratricopeptide repeat Apc3 PF12895.2 ETO35027.1 - 1.9e-12 47.1 22.2 6.7e-05 22.9 1.2 5.7 1 1 5 6 6 6 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO35027.1 - 1.5e-11 44.4 1.5 0.0061 16.8 0.0 5.3 5 1 1 6 6 6 3 Tetratricopeptide repeat SNAP PF14938.1 ETO35027.1 - 1.5e-11 43.9 14.7 5e-05 22.5 0.0 4.7 2 2 1 4 4 4 3 Soluble NSF attachment protein, SNAP TPR_3 PF07720.7 ETO35027.1 - 3.2e-11 42.7 23.5 0.22 11.3 0.5 7.8 7 0 0 7 7 7 5 Tetratricopeptide repeat MIT PF04212.13 ETO35027.1 - 9.6e-09 35.0 27.2 0.17 11.7 0.4 8.6 9 0 0 9 9 9 3 MIT (microtubule interacting and transport) domain PPR PF01535.15 ETO35027.1 - 1.1e-06 28.2 18.7 0.19 11.7 0.0 8.5 10 0 0 10 10 8 2 PPR repeat TPR_21 PF09976.4 ETO35027.1 - 1.4e-05 25.0 1.2 0.0029 17.5 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO35027.1 - 2e-05 23.7 1.1 4.7 6.5 0.0 6.1 7 0 0 7 7 6 1 SHNi-TPR DUF627 PF04781.7 ETO35027.1 - 0.00078 19.0 13.0 3 7.4 0.1 6.1 2 2 4 6 6 6 2 Protein of unknown function (DUF627) Peptidase_C14 PF00656.17 ETO35027.1 - 0.097 12.3 2.3 0.95 9.1 1.6 2.3 1 1 0 1 1 1 0 Caspase domain PPR_2 PF13041.1 ETO35027.1 - 1.2 9.1 16.8 3 7.8 0.1 6.1 8 0 0 8 8 7 0 PPR repeat family Sel1 PF08238.7 ETO35027.1 - 1.4 9.6 24.2 1 10.1 0.1 6.9 7 0 0 7 7 7 0 Sel1 repeat Pep3_Vps18 PF05131.9 ETO35027.1 - 3.5 7.0 13.1 3.8 6.9 0.5 4.9 5 1 1 6 6 5 0 Pep3/Vps18/deep orange family WD40 PF00400.27 ETO35028.1 - 2.8e-19 68.2 0.4 9.4e-10 38.0 0.0 3.7 3 1 1 4 4 4 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO35028.1 - 0.062 12.0 3.1 0.43 9.2 2.3 1.9 1 1 1 2 2 2 0 Nup133 N terminal like DUF454 PF04304.8 ETO35029.1 - 0.057 13.4 1.0 0.057 13.4 0.7 3.8 4 1 0 4 4 4 0 Protein of unknown function (DUF454) CagE_TrbE_VirB PF03135.9 ETO35030.1 - 0.014 15.1 0.0 0.016 14.9 0.0 1.1 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system Nop53 PF07767.6 ETO35033.1 - 0.0055 15.7 1.3 0.0065 15.4 0.9 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Nucleoplasmin PF03066.10 ETO35033.1 - 0.11 12.0 3.2 0.14 11.6 2.2 1.2 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 ETO35033.1 - 0.14 11.4 4.6 0.17 11.1 3.2 1.1 1 0 0 1 1 1 0 NOA36 protein DUF912 PF06024.7 ETO35033.1 - 0.22 11.5 0.9 0.44 10.6 0.6 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2457 PF10446.4 ETO35033.1 - 0.41 9.3 5.8 0.48 9.1 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sporozoite_P67 PF05642.6 ETO35033.1 - 0.57 7.9 4.8 0.69 7.6 3.3 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PBP1_TM PF14812.1 ETO35033.1 - 1.1 9.5 10.9 4.5 7.6 7.6 1.9 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF912 PF06024.7 ETO35034.1 - 0.28 11.2 13.5 0.028 14.4 2.9 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ER_lumen_recept PF00810.13 ETO35034.1 - 1 9.8 8.0 3.9 7.9 0.3 2.4 2 0 0 2 2 2 0 ER lumen protein retaining receptor PARP PF00644.15 ETO35036.1 - 1e-12 47.9 1.4 2.7e-12 46.5 1.0 1.7 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PAGK PF15284.1 ETO35036.1 - 0.064 13.0 0.1 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Phage-encoded virulence factor EVE PF01878.13 ETO35037.1 - 0.016 15.2 0.6 0.086 12.8 0.4 2.1 1 1 0 1 1 1 0 EVE domain Gly-zipper_YMGG PF13441.1 ETO35039.1 - 0.0059 16.0 13.1 0.015 14.7 9.1 1.6 1 0 0 1 1 1 1 YMGG-like Gly-zipper NSP2_assoc PF14758.1 ETO35039.1 - 0.081 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Non-essential region of nsp2 of arterivirus polyprotein DUF456 PF04306.8 ETO35039.1 - 0.088 12.8 2.3 0.16 12.0 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Rick_17kDa_Anti PF05433.10 ETO35039.1 - 0.095 12.3 15.2 0.26 10.9 10.5 1.8 1 1 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 ETO35039.1 - 0.86 9.2 17.9 2.7 7.6 12.0 2.2 1 1 1 2 2 2 0 Glycine zipper Gly-zipper_OmpA PF13436.1 ETO35039.1 - 1.1 8.9 9.3 0.49 10.0 4.5 2.0 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Bacteriocin_IIc PF10439.4 ETO35039.1 - 1.4 9.1 15.6 3.6 7.7 10.8 1.7 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide WD40 PF00400.27 ETO35040.1 - 6.9e-28 95.4 17.1 1.1e-11 44.1 0.2 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO35040.1 - 5.4e-08 31.4 2.4 0.0015 16.7 0.1 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO35040.1 - 0.087 13.0 2.4 1.4 9.2 0.2 2.9 2 1 0 2 2 2 0 Kelch motif Transketolase_C PF02780.15 ETO35041.1 - 4.1e-39 133.3 0.0 1.4e-38 131.5 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain WD40 PF00400.27 ETO35042.1 - 6.2e-19 67.0 6.3 8.7e-10 38.1 0.4 2.8 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO35042.1 - 8.7e-05 20.8 0.7 0.0018 16.4 0.1 2.3 1 1 1 2 2 2 1 Nucleoporin Nup120/160 zf-C3HC4_2 PF13923.1 ETO35042.1 - 0.003 17.5 0.5 0.022 14.7 0.3 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-BED PF02892.10 ETO35042.1 - 0.024 14.3 0.7 0.024 14.3 0.5 3.9 4 0 0 4 4 4 0 BED zinc finger Reo_sigmaC PF04582.7 ETO35042.1 - 0.053 12.7 1.5 0.049 12.7 0.2 1.5 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF1675 PF07897.6 ETO35042.1 - 0.081 12.7 7.1 0.13 12.0 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) WD40 PF00400.27 ETO35044.1 - 1.8e-49 163.9 28.1 4.1e-10 39.1 0.1 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO35044.1 - 8.2e-10 37.4 1.4 0.00062 18.0 0.1 4.0 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO35044.1 - 5.7e-06 25.3 6.4 0.063 12.0 0.3 4.0 2 1 2 4 4 4 3 Nup133 N terminal like Sial-lect-inser PF09264.5 ETO35044.1 - 0.0016 17.8 0.6 0.24 10.6 0.0 2.3 1 1 0 2 2 2 2 Vibrio cholerae sialidase, lectin insertion Methyltransf_25 PF13649.1 ETO35044.1 - 0.063 13.6 0.0 2.7 8.3 0.0 3.0 3 0 0 3 3 3 0 Methyltransferase domain HAD PF12710.2 ETO35044.1 - 0.071 13.2 0.3 0.36 10.9 0.2 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase WD40 PF00400.27 ETO35045.1 - 1.7e-26 91.0 2.2 3.5e-11 42.5 0.0 3.5 4 0 0 4 4 4 3 WD domain, G-beta repeat PQQ_2 PF13360.1 ETO35045.1 - 0.0038 16.7 0.0 0.25 10.7 0.0 1.9 1 1 0 1 1 1 1 PQQ-like domain Nucleoporin_N PF08801.6 ETO35045.1 - 0.0049 15.6 0.4 0.2 10.3 0.0 2.3 1 1 1 2 2 2 2 Nup133 N terminal like BBS2_Mid PF14783.1 ETO35045.1 - 0.027 14.2 0.1 0.36 10.6 0.0 2.5 1 1 2 3 3 3 0 Ciliary BBSome complex subunit 2, middle region MMR_HSR1 PF01926.18 ETO35046.1 - 8.2e-05 22.5 0.2 8.2e-05 22.5 0.1 2.3 2 2 0 2 2 2 1 50S ribosome-binding GTPase DUF815 PF05673.8 ETO35046.1 - 8.3e-05 21.6 0.1 0.00018 20.5 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF815) DUF258 PF03193.11 ETO35046.1 - 0.00011 21.4 0.5 0.00011 21.4 0.3 3.0 3 1 0 3 3 3 1 Protein of unknown function, DUF258 DUF2457 PF10446.4 ETO35046.1 - 0.00062 18.6 17.0 0.00062 18.6 11.8 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) PPV_E1_C PF00519.12 ETO35046.1 - 0.0021 16.7 0.7 1.2 7.6 0.5 2.3 2 0 0 2 2 2 2 Papillomavirus helicase Miro PF08477.8 ETO35046.1 - 0.0024 18.3 1.0 0.0085 16.5 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein ABC_tran PF00005.22 ETO35046.1 - 0.0035 17.6 0.0 0.0035 17.6 0.0 2.3 2 1 0 2 2 1 1 ABC transporter AAA_25 PF13481.1 ETO35046.1 - 0.0081 15.5 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 ETO35046.1 - 0.0091 16.1 0.2 0.0091 16.1 0.1 2.8 2 2 1 3 3 3 1 RNA helicase AAA_PrkA PF08298.6 ETO35046.1 - 0.0095 14.6 0.0 0.017 13.8 0.0 1.4 1 1 0 1 1 1 1 PrkA AAA domain PhoH PF02562.11 ETO35046.1 - 0.012 14.8 0.1 0.022 14.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein T2SE PF00437.15 ETO35046.1 - 0.035 13.0 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 ETO35046.1 - 0.038 13.5 0.0 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CoA_trans PF01144.18 ETO35046.1 - 0.044 12.9 0.0 0.064 12.4 0.0 1.2 1 0 0 1 1 1 0 Coenzyme A transferase IstB_IS21 PF01695.12 ETO35046.1 - 0.046 13.1 0.0 0.098 12.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Sporozoite_P67 PF05642.6 ETO35046.1 - 0.057 11.2 4.6 0.068 11.0 3.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AAA_16 PF13191.1 ETO35046.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 ETO35046.1 - 0.13 12.1 0.5 0.35 10.8 0.4 1.9 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 ETO35046.1 - 0.14 12.0 10.0 4.2 7.1 0.4 3.4 2 1 1 3 3 3 0 Dynamin family PP_M1 PF03012.9 ETO35046.1 - 0.21 10.8 9.8 0.32 10.2 6.8 1.3 1 0 0 1 1 1 0 Phosphoprotein DUF4538 PF15061.1 ETO35046.1 - 0.53 9.6 2.9 1.3 8.3 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) DUF2076 PF09849.4 ETO35046.1 - 0.55 10.2 11.6 0.93 9.4 8.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF1510 PF07423.6 ETO35046.1 - 0.77 9.0 18.5 2.1 7.6 10.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 ETO35046.1 - 0.9 7.4 10.9 1.1 7.2 7.5 1.3 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.11 ETO35046.1 - 1.2 8.0 8.0 1.1 8.1 4.6 1.5 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit FAM176 PF14851.1 ETO35046.1 - 1.8 8.2 7.5 4.5 6.9 5.2 1.7 1 0 0 1 1 1 0 FAM176 family DUF258 PF03193.11 ETO35047.1 - 6.8e-06 25.3 0.1 4.2e-05 22.7 0.1 2.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 ETO35047.1 - 2.4e-05 24.2 0.8 0.00023 21.1 0.1 3.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.22 ETO35047.1 - 0.00011 22.5 0.1 0.00011 22.5 0.1 4.3 4 1 0 4 4 4 1 ABC transporter Miro PF08477.8 ETO35047.1 - 0.00019 21.9 0.5 0.013 15.9 0.1 3.3 2 0 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 ETO35047.1 - 0.036 13.5 0.0 0.079 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 ETO35047.1 - 0.069 13.3 1.5 1.3 9.1 0.0 3.8 4 0 0 4 4 4 0 RNA helicase MoCF_biosynth PF00994.19 ETO35047.1 - 0.073 12.4 0.5 0.82 9.0 0.0 2.8 3 0 0 3 3 3 0 Probable molybdopterin binding domain AAA_16 PF13191.1 ETO35047.1 - 0.22 11.4 2.1 1.6 8.6 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain Ank_2 PF12796.2 ETO35048.1 - 0.0072 16.6 0.8 0.012 15.8 0.6 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO35048.1 - 0.089 12.6 0.0 0.22 11.3 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeat Ank_3 PF13606.1 ETO35048.1 - 0.18 12.1 1.3 0.41 11.0 0.0 2.3 3 0 0 3 3 3 0 Ankyrin repeat Kelch_1 PF01344.20 ETO35050.1 - 2.4e-07 30.1 1.2 0.0013 18.2 0.2 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO35050.1 - 9.1e-06 25.2 4.8 0.0054 16.4 0.1 4.2 4 1 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO35050.1 - 2.4e-05 24.3 4.8 0.12 12.5 0.1 4.7 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.1 ETO35050.1 - 0.00028 20.9 0.1 0.21 11.8 0.0 4.0 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO35050.1 - 0.0017 18.2 2.1 0.46 10.5 0.1 3.9 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO35050.1 - 0.2 11.4 5.1 0.31 10.8 0.2 3.1 2 2 1 3 3 3 0 Galactose oxidase, central domain RE_MjaI PF09568.5 ETO35052.1 - 0.044 13.3 0.2 0.05 13.1 0.2 1.1 1 0 0 1 1 1 0 MjaI restriction endonuclease YSIRK_signal PF04650.12 ETO35053.1 - 1.6 8.3 7.1 1.6 8.3 0.2 3.3 3 0 0 3 3 3 0 YSIRK type signal peptide WD40 PF00400.27 ETO35054.1 - 6.9e-16 57.4 3.8 1.6e-10 40.4 0.1 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat RNA_pol_Rpb1_5 PF04998.12 ETO35054.1 - 0.03 13.5 0.1 0.046 12.9 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Intein_splicing PF14890.1 ETO35054.1 - 0.038 12.8 5.7 0.054 12.3 3.9 1.2 1 0 0 1 1 1 0 Intein splicing domain HTH_19 PF12844.2 ETO35054.1 - 0.044 13.8 1.6 0.099 12.7 0.2 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain WD40 PF00400.27 ETO35055.1 - 1.2e-55 183.5 20.2 1.8e-10 40.3 0.4 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO35055.1 - 2.4e-10 39.1 9.0 0.0038 15.4 0.1 4.5 1 1 2 4 4 4 4 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO35055.1 - 0.00069 19.9 1.8 0.00069 19.9 1.2 2.4 2 0 0 2 2 2 1 TRAF-type zinc finger GEMIN8 PF15348.1 ETO35055.1 - 0.11 12.4 4.7 0.22 11.5 3.2 1.4 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 WD40 PF00400.27 ETO35058.1 - 6.1e-54 178.0 11.7 1.9e-11 43.3 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO35058.1 - 6.1e-07 27.9 12.5 0.39 8.8 0.0 5.8 1 1 3 4 4 4 4 Nucleoporin Nup120/160 DUF727 PF05303.7 ETO35058.1 - 0.017 14.8 0.1 13 5.5 0.0 4.1 4 1 1 5 5 5 0 Protein of unknown function (DUF727) Peptidase_C69 PF03577.10 ETO35058.1 - 0.37 9.6 2.6 4.1 6.1 0.1 3.1 2 2 1 4 4 4 0 Peptidase family C69 PD40 PF07676.7 ETO35058.1 - 5.1 6.8 8.1 14 5.4 0.0 4.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat A_thal_3526 PF09713.5 ETO35059.1 - 0.18 11.9 1.8 0.44 10.7 0.1 2.3 2 0 0 2 2 2 0 Plant protein 1589 of unknown function (A_thal_3526) LMBR1 PF04791.11 ETO35059.1 - 2.9 6.3 4.3 2.4 6.6 0.6 2.0 2 0 0 2 2 2 0 LMBR1-like membrane protein Pkinase PF00069.20 ETO35060.1 - 2.4e-61 207.1 0.0 3.5e-61 206.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO35060.1 - 1.7e-22 79.7 0.1 3.5e-22 78.7 0.1 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 ETO35060.1 - 0.068 12.8 0.1 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family p450 PF00067.17 ETO35061.1 - 5.9e-31 107.5 13.5 8.9e-16 57.4 0.3 3.0 2 1 0 2 2 2 2 Cytochrome P450 WD40 PF00400.27 ETO35062.1 - 9.9e-25 85.4 10.3 8e-09 35.0 0.0 4.5 4 1 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO35062.1 - 1.9e-06 26.3 0.7 0.03 12.4 0.1 2.9 2 1 1 3 3 3 3 Nucleoporin Nup120/160 HARP PF07443.8 ETO35062.1 - 0.14 11.6 0.3 4.3 6.7 0.0 2.4 2 0 0 2 2 2 0 HepA-related protein (HARP) SprA-related PF12118.3 ETO35063.1 - 0.00039 19.8 22.3 0.00039 19.8 15.4 2.7 3 0 0 3 3 3 1 SprA-related family Activator_LAG-3 PF11498.3 ETO35063.1 - 0.0069 15.1 41.2 0.012 14.4 28.5 1.3 1 0 0 1 1 1 1 Transcriptional activator LAG-3 Serinc PF03348.10 ETO35063.1 - 0.093 11.4 5.3 0.15 10.7 3.7 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) GOLD_2 PF13897.1 ETO35063.1 - 0.27 11.4 2.7 0.8 9.9 1.9 1.7 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking zf-DHHC PF01529.15 ETO35063.1 - 0.58 9.5 3.5 0.31 10.4 0.8 1.8 2 0 0 2 2 2 0 DHHC palmitoyltransferase AAA_23 PF13476.1 ETO35063.1 - 0.62 10.3 16.0 0.17 12.1 8.4 1.9 2 0 0 2 2 2 0 AAA domain Peptidase_U57 PF05582.7 ETO35063.1 - 0.74 8.7 6.1 1.4 7.8 4.2 1.3 1 0 0 1 1 1 0 YabG peptidase U57 SecA_DEAD PF07517.9 ETO35063.1 - 1 8.5 9.0 1.6 7.9 6.2 1.2 1 0 0 1 1 1 0 SecA DEAD-like domain YfhO PF09586.5 ETO35063.1 - 8.7 4.2 8.4 11 3.9 5.8 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO OATP PF03137.15 ETO35063.1 - 9.2 4.1 8.9 15 3.4 6.2 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family GvpK PF05121.7 ETO35064.1 - 0.039 13.7 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 Gas vesicle protein K YqfQ PF14181.1 ETO35064.1 - 7.2 6.6 9.8 0.31 11.0 0.6 2.5 2 0 0 2 2 2 0 YqfQ-like protein MBOAT_2 PF13813.1 ETO35067.1 - 0.0069 16.4 0.5 0.014 15.4 0.4 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF423 PF04241.10 ETO35067.1 - 5.5 6.9 6.8 5.9 6.8 2.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF423) E3_UbLigase_R4 PF13764.1 ETO35068.1 - 9.5e-74 248.7 2.8 1.8e-69 234.5 1.4 2.4 2 1 0 2 2 2 2 E3 ubiquitin-protein ligase UBR4 E3_UbLigase_R4 PF13764.1 ETO35069.1 - 1e-46 159.3 3.9 1.9e-46 158.4 2.7 1.4 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase UBR4 TEP1_N PF05386.6 ETO35070.1 - 0.079 12.4 0.0 0.24 10.8 0.0 1.8 1 0 0 1 1 1 0 TEP1 N-terminal domain DUF3595 PF12166.3 ETO35070.1 - 5.4 5.7 7.8 6.9 5.3 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) DUF4551 PF15087.1 ETO35070.1 - 6.4 5.0 7.5 8.7 4.5 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Fer4_12 PF13353.1 ETO35073.1 - 0.13 12.3 1.0 7.5 6.6 0.1 2.1 2 0 0 2 2 2 0 4Fe-4S single cluster domain PEN-2 PF10251.4 ETO35073.1 - 0.64 10.2 3.8 0.26 11.5 0.7 1.7 1 1 1 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase Snf7 PF03357.16 ETO35074.1 - 7.3e-25 87.3 31.6 6.5e-22 77.7 9.3 2.2 1 1 1 2 2 2 2 Snf7 Laminin_II PF06009.7 ETO35074.1 - 0.0016 18.1 7.0 0.041 13.6 0.6 2.3 2 0 0 2 2 2 2 Laminin Domain II Citrate_ly_lig PF08218.6 ETO35074.1 - 0.0045 16.4 0.7 0.014 14.8 0.0 2.1 2 1 1 3 3 3 1 Citrate lyase ligase C-terminal domain TBPIP PF07106.8 ETO35074.1 - 0.037 13.5 9.2 0.19 11.2 1.2 2.3 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Nup54 PF13874.1 ETO35074.1 - 0.067 12.8 5.7 0.22 11.1 0.3 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 NPV_P10 PF05531.7 ETO35074.1 - 0.12 12.6 7.0 1.5 9.1 1.0 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Glutaredoxin PF00462.19 ETO35074.1 - 0.14 12.1 0.3 0.14 12.1 0.2 2.7 3 1 1 4 4 3 0 Glutaredoxin Syntaxin-6_N PF09177.6 ETO35074.1 - 0.18 12.2 6.7 0.31 11.4 0.2 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal FlaC_arch PF05377.6 ETO35074.1 - 0.37 10.7 7.8 1.4 8.9 0.7 3.3 3 1 1 4 4 3 0 Flagella accessory protein C (FlaC) ISG65-75 PF11727.3 ETO35074.1 - 0.85 8.6 13.7 1.6 7.7 1.7 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein COG5 PF10392.4 ETO35074.1 - 0.97 9.3 6.2 2.2 8.2 0.3 2.3 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Nup88 PF10168.4 ETO35074.1 - 1.1 7.0 6.9 0.45 8.2 1.4 2.0 2 0 0 2 2 2 0 Nuclear pore component Halogen_Hydrol PF10112.4 ETO35074.1 - 1.2 8.5 7.2 0.26 10.6 0.9 2.1 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF972 PF06156.8 ETO35074.1 - 1.6 9.1 8.8 2.9 8.3 0.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF948 PF06103.6 ETO35074.1 - 1.6 8.6 6.3 3.3 7.6 0.7 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2730 PF10805.3 ETO35074.1 - 2.4 7.9 7.7 12 5.7 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Prefoldin_2 PF01920.15 ETO35074.1 - 4.4 7.1 17.5 1.6 8.5 4.4 3.3 2 1 0 2 2 2 0 Prefoldin subunit Sulfatase_C PF14707.1 ETO35074.1 - 4.7 7.4 5.9 4.5 7.5 0.1 2.5 2 1 1 3 3 2 0 C-terminal region of aryl-sulfatase DUF2852 PF11014.3 ETO35074.1 - 6.4 6.7 8.3 8.6 6.3 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2852) Fib_alpha PF08702.5 ETO35074.1 - 6.9 6.7 8.8 1.8 8.6 0.6 2.4 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.1 ETO35074.1 - 9.6 5.0 9.1 12 4.7 5.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Ax_dynein_light PF10211.4 ETO35074.1 - 9.7 5.9 11.2 1.9 8.3 2.6 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain Cauli_DNA-bind PF03310.8 ETO35074.1 - 10 6.0 8.8 3.4 7.5 0.9 2.4 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein DUF3841 PF12952.2 ETO35075.1 - 0.031 13.7 0.4 0.038 13.4 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3841) DUF722 PF05263.6 ETO35075.1 - 0.033 14.3 1.8 0.039 14.0 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF722) TRAP-gamma PF07074.7 ETO35075.1 - 6.5 6.2 8.2 4.6 6.7 1.5 2.1 1 1 1 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) ELMO_CED12 PF04727.8 ETO35076.1 - 0.00078 19.0 0.2 0.002 17.6 0.2 1.7 1 0 0 1 1 1 1 ELMO/CED-12 family DUF1754 PF08555.5 ETO35076.1 - 0.0082 16.7 6.4 0.0082 16.7 4.4 2.0 2 1 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) Gti1_Pac2 PF09729.4 ETO35076.1 - 1.7 8.4 8.1 4.1 7.2 5.6 1.6 1 1 0 1 1 1 0 Gti1/Pac2 family Rtf2 PF04641.7 ETO35076.1 - 3.4 6.7 9.1 0.9 8.6 3.8 1.8 2 0 0 2 2 2 0 Rtf2 RING-finger Kelch_6 PF13964.1 ETO35077.1 - 5e-08 32.7 1.8 0.27 11.4 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO35077.1 - 4.5e-07 29.3 1.9 0.056 12.9 0.6 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 ETO35077.1 - 0.001 18.7 4.4 1.8 8.4 0.0 4.3 4 1 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO35077.1 - 0.017 14.8 0.7 16 5.3 0.0 3.8 2 1 1 3 3 3 0 Galactose oxidase, central domain WD40 PF00400.27 ETO35078.1 - 5.3e-23 80.0 5.9 3.2e-13 48.9 0.7 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO35078.1 - 1.5e-07 29.9 0.7 0.00017 19.8 0.0 2.1 1 1 0 2 2 2 2 Nucleoporin Nup120/160 WD40 PF00400.27 ETO35079.1 - 3.2e-12 45.8 11.9 3.3e-08 33.1 1.8 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat DUF707 PF05212.7 ETO35079.1 - 0.0031 16.6 0.5 0.0041 16.2 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF707) WD40 PF00400.27 ETO35080.1 - 9.9e-25 85.4 7.0 1.5e-09 37.3 0.1 4.2 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO35080.1 - 2.5e-06 25.9 1.0 0.089 10.9 0.0 3.3 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO35080.1 - 0.0019 17.0 1.1 0.4 9.3 0.0 2.4 1 1 1 2 2 2 2 Nup133 N terminal like zf-SNAP50_C PF12251.3 ETO35081.1 - 7.1e-46 156.0 8.0 8.4e-46 155.8 5.5 1.0 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal zf-Dof PF02701.10 ETO35081.1 - 6.9e-05 22.6 5.3 0.00013 21.7 3.7 1.5 1 0 0 1 1 1 1 Dof domain, zinc finger DCAF15_WD40 PF14939.1 ETO35081.1 - 0.0043 16.4 0.3 0.0053 16.1 0.2 1.1 1 0 0 1 1 1 1 DDB1-and CUL4-substrate receptor 15, WD repeat C2 PF00168.25 ETO35082.1 - 3.7e-20 71.5 0.1 7.1e-20 70.6 0.1 1.5 1 0 0 1 1 1 1 C2 domain Spc7 PF08317.6 ETO35082.1 - 0.01 14.5 24.3 0.016 13.9 16.8 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Mod_r PF07200.8 ETO35082.1 - 0.039 13.8 22.9 0.14 12.0 7.8 2.5 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein AAA_13 PF13166.1 ETO35082.1 - 0.56 8.6 22.2 0.77 8.1 15.4 1.2 1 0 0 1 1 1 0 AAA domain ADIP PF11559.3 ETO35082.1 - 0.71 9.7 29.0 1.6 8.5 6.3 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.10 ETO35082.1 - 0.77 9.2 36.2 0.35 10.3 2.3 4.3 2 2 2 4 4 4 0 Septum formation initiator SprA-related PF12118.3 ETO35082.1 - 4.5 6.5 15.3 6.2 6.0 10.6 1.1 1 0 0 1 1 1 0 SprA-related family Atg14 PF10186.4 ETO35082.1 - 9.7 5.0 27.8 3 6.7 8.4 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Gaa1 PF04114.9 ETO35083.1 - 4.6e-15 55.3 7.1 9e-08 31.2 1.3 2.6 1 1 0 2 2 2 2 Gaa1-like, GPI transamidase component DUF843 PF05814.6 ETO35083.1 - 1.5 8.6 10.4 5.6 6.8 0.0 3.5 3 0 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) YqzH PF14164.1 ETO35084.1 - 0.0077 16.1 0.4 0.03 14.2 0.2 2.0 1 0 0 1 1 1 1 YqzH-like protein DUF1675 PF07897.6 ETO35085.1 - 0.0053 16.6 0.2 0.0075 16.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1675) SPRY PF00622.23 ETO35086.1 - 0.00097 19.2 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 SPRY domain SAM_2 PF07647.12 ETO35088.1 - 0.015 15.1 0.2 0.033 14.0 0.1 1.6 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) WD40 PF00400.27 ETO35090.1 - 7.8e-32 107.9 12.4 2.7e-12 46.0 0.0 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat AAA_22 PF13401.1 ETO35090.1 - 0.0002 21.5 0.0 0.00095 19.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain PD40 PF07676.7 ETO35090.1 - 0.00024 20.6 0.3 2.1 8.0 0.1 3.7 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat AAA_17 PF13207.1 ETO35090.1 - 0.00033 21.4 0.3 0.0033 18.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 ETO35090.1 - 0.00048 19.8 4.4 0.00056 19.6 0.0 2.9 3 1 0 3 3 3 1 Archaeal ATPase UPF0079 PF02367.12 ETO35090.1 - 0.00093 18.8 0.0 0.0024 17.5 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 PQQ_2 PF13360.1 ETO35090.1 - 0.0043 16.5 0.1 0.098 12.1 0.1 2.2 1 1 1 2 2 2 1 PQQ-like domain PduV-EutP PF10662.4 ETO35090.1 - 0.0068 15.9 0.0 0.019 14.4 0.0 1.8 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Kinesin PF00225.18 ETO35090.1 - 0.012 14.3 1.6 0.012 14.3 0.1 1.7 2 0 0 2 2 2 0 Kinesin motor domain NACHT PF05729.7 ETO35090.1 - 0.015 14.9 0.0 0.21 11.2 0.0 2.6 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 ETO35090.1 - 0.017 15.2 0.2 0.09 12.9 0.0 2.4 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.22 ETO35090.1 - 0.039 14.2 0.0 0.41 10.9 0.0 2.8 3 0 0 3 3 3 0 ABC transporter TPR_12 PF13424.1 ETO35091.1 - 2.5e-29 101.0 17.1 1.7e-16 59.9 0.6 3.2 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO35091.1 - 2.8e-10 39.3 6.7 0.00035 20.0 1.9 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO35091.1 - 6.2e-10 38.1 1.9 2.1e-05 23.9 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO35091.1 - 2.7e-09 36.6 0.5 5.1e-05 23.0 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO35091.1 - 2.8e-07 29.9 2.5 0.007 16.1 0.6 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO35091.1 - 4.7e-07 29.3 9.5 0.0061 16.1 0.6 3.4 3 0 0 3 3 3 2 TPR repeat TPR_17 PF13431.1 ETO35091.1 - 0.0017 18.4 3.1 0.063 13.5 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO35091.1 - 0.017 14.8 12.0 0.15 11.9 0.9 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat CDC37_N PF03234.9 ETO35092.1 - 1.9 8.7 5.7 2.5 8.4 4.0 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding MMR1 PF08505.5 ETO35092.1 - 2.5 8.0 10.9 0.21 11.5 4.3 1.6 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Myotub-related PF06602.9 ETO35093.1 - 3.6e-70 236.5 1.5 4.1e-70 236.3 1.1 1.0 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Nop16 PF09420.5 ETO35094.1 - 2.5e-12 47.1 17.8 1.1e-11 45.1 12.3 2.1 1 1 0 1 1 1 1 Ribosome biogenesis protein Nop16 FAM60A PF15396.1 ETO35094.1 - 0.22 11.2 5.8 0.25 11.0 4.0 1.2 1 0 0 1 1 1 0 Protein Family FAM60A UCH PF00443.24 ETO35095.1 - 5.6e-35 120.7 7.3 3e-34 118.3 0.5 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO35095.1 - 2.7e-16 59.8 0.0 2.7e-16 59.8 0.0 2.6 2 1 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase PapG_N PF03627.8 ETO35095.1 - 0.011 15.1 0.1 0.028 13.8 0.0 1.6 1 0 0 1 1 1 0 PapG carbohydrate binding domain OAD_gamma PF04277.8 ETO35097.1 - 7.9 6.9 8.4 1.3 9.4 1.9 2.5 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Bromodomain PF00439.20 ETO35098.1 - 0.00093 19.0 0.1 0.0021 17.9 0.1 1.6 1 0 0 1 1 1 1 Bromodomain Prp18 PF02840.10 ETO35098.1 - 0.078 12.7 0.9 0.61 9.9 0.2 2.4 1 1 0 2 2 2 0 Prp18 domain Relaxase PF03432.9 ETO35099.1 - 0.0083 15.5 2.2 0.0096 15.3 1.5 1.0 1 0 0 1 1 1 1 Relaxase/Mobilisation nuclease domain VTC PF09359.5 ETO35099.1 - 0.014 14.3 4.3 0.14 11.1 1.1 2.0 2 0 0 2 2 2 0 VTC domain FliS PF02561.9 ETO35099.1 - 0.041 13.7 1.1 0.054 13.3 0.7 1.1 1 0 0 1 1 1 0 Flagellar protein FliS COQ9 PF08511.6 ETO35100.1 - 0.044 13.3 0.3 0.27 10.7 0.2 2.1 1 1 0 1 1 1 0 COQ9 Ank PF00023.25 ETO35103.1 - 0.00069 19.3 0.0 0.0015 18.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.1 ETO35103.1 - 0.00098 19.3 0.1 0.0033 17.6 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF3908 PF13048.1 ETO35103.1 - 0.0023 17.9 3.0 0.021 14.8 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3908) Ank_2 PF12796.2 ETO35103.1 - 0.0026 18.0 0.0 0.0038 17.5 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO35103.1 - 0.026 14.7 0.4 0.073 13.3 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeat YfmQ PF10787.4 ETO35103.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein from bacillus cereus group SUFU_C PF12470.3 ETO35104.1 - 0.16 11.5 2.3 0.2 11.2 1.6 1.1 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain cNMP_binding PF00027.24 ETO35106.1 - 1.5e-05 24.7 0.0 3.2e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain ALMT PF11744.3 ETO35106.1 - 0.8 8.2 6.5 1.6 7.2 4.5 1.5 1 0 0 1 1 1 0 Aluminium activated malate transporter zf-RING_5 PF14634.1 ETO35106.1 - 2.9 7.7 20.1 0.018 14.7 7.4 2.3 2 0 0 2 2 2 0 zinc-RING finger domain WD40 PF00400.27 ETO35107.1 - 2.7e-57 188.7 25.5 5.6e-12 45.0 0.2 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO35107.1 - 9.5e-09 33.9 5.6 0.28 9.2 0.0 5.0 1 1 3 5 5 5 5 Nucleoporin Nup120/160 DUF1044 PF06296.7 ETO35110.1 - 0.004 16.9 1.3 0.55 10.0 0.1 3.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1044) DUF1546 PF07571.8 ETO35110.1 - 0.0079 16.2 0.0 10 6.2 0.0 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1546) 120_Rick_ant PF12574.3 ETO35112.1 - 0.012 14.7 0.0 0.021 13.9 0.0 1.4 1 1 0 1 1 1 0 120 KDa Rickettsia surface antigen TFIIE_alpha PF02002.12 ETO35112.1 - 0.016 14.6 0.6 0.31 10.5 0.1 2.8 2 0 0 2 2 2 0 TFIIE alpha subunit WD40 PF00400.27 ETO35114.1 - 8.9e-46 152.1 8.1 4.5e-12 45.3 0.1 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO35114.1 - 1.3e-06 26.8 2.3 0.21 9.6 0.1 3.6 2 1 2 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO35114.1 - 0.014 15.0 1.0 0.18 11.5 0.1 2.7 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A DUF3601 PF12208.3 ETO35114.1 - 0.046 13.6 0.1 0.96 9.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3601) MC1 PF05854.6 ETO35114.1 - 0.091 12.7 0.0 4.5 7.3 0.0 2.7 2 1 0 2 2 2 0 Non-histone chromosomal protein MC1 Kelch_6 PF13964.1 ETO35114.1 - 1 9.6 5.6 21 5.5 0.1 3.9 4 0 0 4 4 4 0 Kelch motif WD40 PF00400.27 ETO35115.1 - 9.2e-39 129.9 12.9 1.7e-12 46.6 0.0 4.6 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO35115.1 - 2.5e-09 35.8 0.8 0.017 13.2 0.0 3.9 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO35115.1 - 0.044 13.9 3.1 8.3 6.7 0.2 3.6 3 1 1 4 4 4 0 Kelch motif RPA_C PF08784.6 ETO35118.1 - 0.00053 20.3 0.1 0.0006 20.1 0.1 1.2 1 0 0 1 1 1 1 Replication protein A C terminal Proteasome PF00227.21 ETO35119.1 - 4.5e-15 55.4 0.0 1.2e-14 54.0 0.0 1.6 1 1 0 1 1 1 1 Proteasome subunit WD40 PF00400.27 ETO35120.1 - 4.8e-58 191.0 15.2 6.1e-12 44.9 0.1 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO35120.1 - 4e-09 35.1 4.7 0.048 11.7 0.3 5.3 1 1 3 4 4 4 4 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO35120.1 - 0.014 15.1 9.9 0.15 11.7 0.7 3.4 2 2 2 4 4 4 0 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 ETO35120.1 - 0.026 14.0 0.1 2 7.8 0.0 3.1 2 1 1 4 4 4 0 PQQ-like domain Kelch_6 PF13964.1 ETO35120.1 - 0.035 14.2 7.9 13 6.1 0.1 5.0 5 0 0 5 5 5 0 Kelch motif WD40 PF00400.27 ETO35121.1 - 5.2e-08 32.4 0.1 1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 WD domain, G-beta repeat WD40 PF00400.27 ETO35122.1 - 3.6e-10 39.3 0.1 0.00028 20.6 0.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat WD40 PF00400.27 ETO35123.1 - 8.5e-66 215.6 17.9 2.7e-12 46.0 0.0 8.2 7 1 1 8 8 8 6 WD domain, G-beta repeat Kelch_4 PF13418.1 ETO35123.1 - 1.7e-07 30.8 0.1 6.3e-05 22.6 0.1 3.2 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO35123.1 - 2.1e-07 30.8 8.7 0.0002 21.3 0.2 6.1 8 0 0 8 8 8 2 Kelch motif Nup160 PF11715.3 ETO35123.1 - 1.9e-06 26.3 3.2 0.25 9.4 0.0 4.7 2 1 1 4 4 4 2 Nucleoporin Nup120/160 Kelch_1 PF01344.20 ETO35123.1 - 0.00011 21.6 1.4 0.072 12.6 0.6 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO35123.1 - 0.00017 21.1 3.2 0.011 15.4 0.3 4.8 5 0 0 5 5 5 1 Kelch motif Nbas_N PF15492.1 ETO35123.1 - 0.0005 19.2 0.6 0.016 14.3 0.0 3.4 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 ETO35123.1 - 0.0021 16.4 0.2 0.44 8.7 0.0 2.6 2 0 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.7 ETO35123.1 - 0.0047 16.5 8.8 4.6 7.0 0.1 4.9 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Kelch_5 PF13854.1 ETO35123.1 - 0.0057 16.5 3.1 5.3 7.1 0.5 3.9 4 0 0 4 4 3 1 Kelch motif Resistin PF06954.6 ETO35123.1 - 0.055 13.7 0.0 46 4.3 0.0 3.5 2 1 1 3 3 3 0 Resistin PA14 PF07691.7 ETO35123.1 - 0.073 12.7 0.6 1.2 8.7 0.0 2.9 2 1 1 3 3 3 0 PA14 domain Kelch_3 PF13415.1 ETO35123.1 - 0.14 12.3 0.1 1 9.6 0.0 2.6 2 0 0 2 2 1 0 Galactose oxidase, central domain Proteasome_A_N PF10584.4 ETO35123.1 - 4.8 6.6 10.5 2.4 7.5 0.0 4.4 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature SKG6 PF08693.5 ETO35124.1 - 1.9 7.8 6.5 0.71 9.2 1.0 2.3 2 0 0 2 2 2 0 Transmembrane alpha-helix domain WD40 PF00400.27 ETO35125.1 - 1.1e-20 72.6 2.3 1.6e-10 40.4 0.1 3.6 3 1 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO35125.1 - 0.00042 18.5 0.7 0.039 12.0 0.0 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO35125.1 - 0.071 11.8 0.1 0.19 10.4 0.1 1.6 1 1 0 1 1 1 0 Nup133 N terminal like Rft-1 PF04506.8 ETO35125.1 - 0.077 11.3 0.0 0.096 11.0 0.0 1.1 1 0 0 1 1 1 0 Rft protein Transket_pyr PF02779.19 ETO35126.1 - 1.9e-57 193.6 0.0 8e-57 191.5 0.0 1.9 1 1 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 ETO35126.1 - 7.1e-51 172.7 0.0 1.2e-50 171.9 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component WD40 PF00400.27 ETO35127.1 - 4.8e-23 80.1 4.0 4e-11 42.3 0.2 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO35127.1 - 2.2e-05 22.8 0.5 0.019 13.1 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Endotoxin_C PF03944.9 ETO35127.1 - 0.084 12.9 0.5 0.14 12.2 0.3 1.3 1 0 0 1 1 1 0 delta endotoxin WD40 PF00400.27 ETO35128.1 - 1.3e-66 218.2 25.7 1e-11 44.2 0.4 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO35128.1 - 2.6e-13 48.9 7.2 0.072 11.2 0.0 6.0 2 1 3 6 6 6 6 Nucleoporin Nup120/160 Ras PF00071.17 ETO35129.1 - 8.7e-37 125.9 0.0 1.4e-36 125.3 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO35129.1 - 1.7e-15 57.5 0.0 3.7e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO35129.1 - 3.6e-11 42.6 0.0 6.2e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETO35129.1 - 4.1e-07 29.3 0.0 7e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 ETO35129.1 - 5e-07 29.3 0.0 8.6e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 ETO35129.1 - 1.1e-05 25.2 0.0 2.7e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 ETO35129.1 - 0.0041 16.3 0.0 0.0081 15.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Band_7 PF01145.20 ETO35130.1 - 0.0021 17.9 0.0 0.89 9.4 0.0 2.2 2 0 0 2 2 2 2 SPFH domain / Band 7 family Clat_adaptor_s PF01217.15 ETO35131.1 - 2.8e-27 95.1 12.4 4.4e-19 68.6 2.8 2.4 1 1 1 2 2 2 2 Clathrin adaptor complex small chain DUF3450 PF11932.3 ETO35132.1 - 0.0005 19.4 0.2 0.00072 18.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Vps53_N PF04100.7 ETO35132.1 - 0.0099 14.6 0.6 0.013 14.2 0.4 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF4482 PF14818.1 ETO35132.1 - 0.011 16.3 2.9 0.014 16.0 2.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4482) Tropomyosin_1 PF12718.2 ETO35132.1 - 0.019 14.8 1.3 0.027 14.2 0.9 1.3 1 0 0 1 1 1 0 Tropomyosin like BLOC1_2 PF10046.4 ETO35132.1 - 0.022 14.8 2.6 0.022 14.8 1.8 1.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3373 PF11853.3 ETO35132.1 - 0.023 13.2 0.6 0.026 13.0 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) HAUS4 PF14735.1 ETO35132.1 - 0.038 13.2 1.4 0.063 12.5 1.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 Rop-like PF05082.8 ETO35132.1 - 0.1 12.0 0.1 0.21 11.0 0.1 1.5 1 0 0 1 1 1 0 Rop-like BBS2_N PF14781.1 ETO35133.1 - 0.0044 16.6 0.0 1.4 8.5 0.0 2.4 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, N-terminal CNH PF00780.17 ETO35133.1 - 0.023 14.1 0.0 0.063 12.6 0.0 1.7 2 0 0 2 2 2 0 CNH domain Nucleoporin_N PF08801.6 ETO35133.1 - 0.028 13.1 0.0 0.053 12.2 0.0 1.5 1 1 0 1 1 1 0 Nup133 N terminal like PQQ_3 PF13570.1 ETO35133.1 - 0.39 11.0 4.5 2.4 8.5 0.0 3.0 4 0 0 4 4 4 0 PQQ-like domain WD40 PF00400.27 ETO35134.1 - 5.7e-76 247.9 18.7 3.4e-14 52.0 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO35134.1 - 5.1e-15 55.6 0.7 1.9e-05 24.4 0.0 4.0 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO35134.1 - 1.3e-09 36.7 5.4 0.19 9.8 0.0 5.3 1 1 4 5 5 5 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO35134.1 - 8.8e-07 28.6 0.3 2.2e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 PQQ-like domain PD40 PF07676.7 ETO35134.1 - 2.7e-06 26.8 16.5 0.17 11.5 0.1 6.4 6 0 0 6 6 6 3 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO35134.1 - 3.2e-05 24.0 0.4 14 6.0 0.0 4.4 2 1 2 4 4 4 1 Resistin Cytochrom_D1 PF02239.11 ETO35134.1 - 6.2e-05 21.4 2.4 0.059 11.6 0.1 2.7 1 1 2 3 3 3 3 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO35134.1 - 0.00017 20.8 0.8 2.4 7.2 0.0 3.9 1 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 ETO35134.1 - 0.0024 16.7 9.7 1.1 7.8 0.1 4.5 2 1 1 4 4 4 3 Nup133 N terminal like TFIIIC_delta PF12657.2 ETO35134.1 - 0.025 14.2 1.3 4.9 6.8 0.0 2.9 2 2 0 2 2 2 0 Transcription factor IIIC subunit delta N-term DUF1510 PF07423.6 ETO35135.1 - 0.00025 20.5 4.5 0.00025 20.5 3.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) SpoIIIAH PF12685.2 ETO35135.1 - 0.0007 19.1 5.5 0.017 14.6 1.8 2.4 2 0 0 2 2 2 1 SpoIIIAH-like protein DUF2417 PF10329.4 ETO35135.1 - 0.03 13.7 0.0 0.17 11.2 0.0 2.2 2 1 0 2 2 2 0 Region of unknown function (DUF2417) Ctr PF04145.10 ETO35135.1 - 0.04 13.9 9.7 4.9 7.1 0.0 3.5 2 1 1 3 3 3 0 Ctr copper transporter family CDC45 PF02724.9 ETO35135.1 - 0.15 10.0 12.9 0.014 13.4 5.3 1.7 2 0 0 2 2 2 0 CDC45-like protein FtsX PF02687.16 ETO35135.1 - 0.38 10.5 2.9 0.4 10.4 0.8 1.8 2 0 0 2 2 2 0 FtsX-like permease family Kei1 PF08552.6 ETO35135.1 - 0.59 9.7 6.9 0.85 9.2 3.2 2.3 1 1 1 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Nucleoside_tran PF01733.13 ETO35135.1 - 0.86 8.6 5.6 14 4.7 3.8 2.3 1 1 0 1 1 1 0 Nucleoside transporter LMBR1 PF04791.11 ETO35135.1 - 1.3 7.4 6.6 2.2 6.7 4.1 1.6 1 1 0 1 1 1 0 LMBR1-like membrane protein PIG-P PF08510.7 ETO35135.1 - 2.6 7.6 7.9 38 3.9 4.5 2.8 2 1 0 2 2 2 0 PIG-P DUF4512 PF14975.1 ETO35135.1 - 3.2 8.6 8.2 1.2 9.9 3.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) WD40 PF00400.27 ETO35136.1 - 3.3e-73 239.1 10.2 7.9e-11 41.4 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO35136.1 - 1.8e-09 36.3 6.6 0.029 12.5 0.0 5.1 1 1 4 5 5 5 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO35136.1 - 2e-06 27.4 1.9 8.4e-06 25.4 1.1 2.5 1 1 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO35136.1 - 8.9e-06 24.2 1.8 0.019 13.2 0.0 3.4 1 1 3 4 4 4 3 Cytochrome D1 heme domain Nbas_N PF15492.1 ETO35136.1 - 0.00017 20.7 0.6 0.47 9.5 0.0 3.3 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 ETO35136.1 - 0.00037 20.0 2.4 8.1 6.2 0.1 4.7 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat PLD_C PF12357.3 ETO35136.1 - 0.0021 17.5 0.3 34 4.0 0.0 4.9 4 1 1 5 5 5 0 Phospholipase D C terminal Me-amine-dh_H PF06433.6 ETO35136.1 - 0.0032 16.1 0.2 5.7 5.4 0.0 3.1 3 0 0 3 3 3 2 Methylamine dehydrogenase heavy chain (MADH) Gmad1 PF10647.4 ETO35136.1 - 0.023 14.1 0.0 0.25 10.6 0.0 2.4 2 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain PQQ PF01011.16 ETO35136.1 - 0.029 13.9 0.0 6.3 6.5 0.0 4.2 5 0 0 5 5 5 0 PQQ enzyme repeat Resistin PF06954.6 ETO35136.1 - 0.084 13.1 0.1 59 4.0 0.0 4.3 2 2 1 5 5 5 0 Resistin DUF3732 PF12532.3 ETO35136.1 - 0.1 12.1 1.2 15 5.0 0.0 3.9 2 1 4 6 6 6 0 Protein of unknown function (DUF3732) PH PF00169.24 ETO35137.1 - 4e-15 55.8 0.2 9.6e-15 54.6 0.1 1.6 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 ETO35137.1 - 7.7e-06 26.1 3.8 5.1e-05 23.4 2.7 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 ETO35137.1 - 0.00048 19.9 0.0 0.00084 19.1 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 ETO35137.1 - 0.0074 16.3 0.3 0.014 15.4 0.2 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain tRNA-synt_2b PF00587.20 ETO35138.1 - 5.8e-54 182.2 0.2 4.6e-53 179.3 0.0 2.6 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 ETO35138.1 - 2.2e-12 46.7 0.0 1.2e-11 44.4 0.0 2.3 2 0 0 2 2 2 1 Anticodon binding domain Kelch_2 PF07646.10 ETO35139.1 - 0.0027 17.4 5.1 17 5.3 0.0 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 ETO35139.1 - 0.0084 16.2 4.5 2.1 8.6 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO35139.1 - 0.09 12.5 0.5 6.1 6.6 0.0 3.1 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO35139.1 - 0.43 10.1 4.2 10 5.7 0.0 3.2 3 0 0 3 3 3 0 Kelch motif WD40 PF00400.27 ETO35140.1 - 3e-49 163.2 9.5 1.3e-12 47.0 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 ETO35140.1 - 2.7e-11 43.5 0.2 0.00011 22.0 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO35140.1 - 1.5e-07 30.9 9.2 2.3 7.9 0.0 6.0 6 0 0 6 6 6 4 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO35140.1 - 8.8e-07 27.5 0.1 0.0022 16.3 0.0 3.1 1 1 1 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.3 ETO35140.1 - 2.5e-06 25.9 2.3 0.26 9.3 0.0 3.6 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO35140.1 - 5.6e-06 25.3 4.9 0.43 9.2 0.0 4.7 1 1 4 5 5 5 4 Nup133 N terminal like PQQ_2 PF13360.1 ETO35140.1 - 1.1e-05 25.0 0.0 0.00075 19.0 0.0 2.3 1 1 0 1 1 1 1 PQQ-like domain DPPIV_N PF00930.16 ETO35140.1 - 0.00029 19.5 0.0 3.7 6.0 0.0 3.9 1 1 4 5 5 5 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Proteasome_A_N PF10584.4 ETO35140.1 - 0.00048 19.3 9.0 13 5.1 0.0 5.6 5 0 0 5 5 5 1 Proteasome subunit A N-terminal signature Hira PF07569.6 ETO35140.1 - 0.01 15.0 0.2 3.3 6.8 0.0 3.5 2 2 1 4 4 4 0 TUP1-like enhancer of split UN_NPL4 PF11543.3 ETO35140.1 - 0.018 15.3 0.5 1.3 9.3 0.0 3.3 3 1 0 3 3 3 0 Nuclear pore localisation protein NPL4 WD40 PF00400.27 ETO35141.1 - 2e-19 68.6 1.6 5e-11 42.0 0.0 3.0 3 1 0 3 3 3 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO35141.1 - 0.0024 16.7 0.3 0.63 8.7 0.0 2.1 1 1 1 2 2 2 2 Nup133 N terminal like Nup160 PF11715.3 ETO35141.1 - 0.0081 14.3 0.0 0.15 10.1 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO35141.1 - 0.021 14.5 0.7 0.67 9.6 0.2 2.3 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A HAD PF12710.2 ETO35141.1 - 0.038 14.1 0.0 0.088 12.9 0.0 1.4 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase GDPD PF03009.12 ETO35144.1 - 0.1 12.0 0.4 0.11 11.9 0.3 1.1 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Inhibitor_I24 PF10465.4 ETO35144.1 - 0.11 12.2 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 PinA peptidase inhibitor CAP_GLY PF01302.20 ETO35145.1 - 1.2e-08 34.5 0.3 2e-08 33.7 0.2 1.3 1 0 0 1 1 1 1 CAP-Gly domain Tissue_fac PF01108.12 ETO35146.1 - 0.037 13.7 0.1 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 Tissue factor DUF3988 PF13149.1 ETO35147.1 - 0.0061 16.1 1.9 0.0095 15.4 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3988) Menin PF05053.8 ETO35147.1 - 0.19 9.8 5.5 0.18 9.9 3.8 1.2 1 0 0 1 1 1 0 Menin DDHD PF02862.12 ETO35147.1 - 0.62 9.8 8.3 0.76 9.5 5.7 1.1 1 0 0 1 1 1 0 DDHD domain Colicin_D PF11429.3 ETO35147.1 - 0.87 9.7 0.0 0.87 9.7 0.0 2.9 2 1 0 3 3 3 0 Colicin D Lipl32 PF12103.3 ETO35148.1 - 0.099 12.0 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Surface lipoprotein of Spirochaetales order KMP11 PF03037.11 ETO35148.1 - 0.2 12.2 1.3 0.3 11.7 0.4 1.7 1 1 1 2 2 2 0 Kinetoplastid membrane protein 11 Helitron_like_N PF14214.1 ETO35151.1 - 0.0017 18.1 0.1 0.0026 17.4 0.0 1.4 1 1 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF3007 PF11460.3 ETO35151.1 - 0.069 13.2 1.5 0.11 12.6 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3007) DUF626 PF04776.7 ETO35151.1 - 0.11 12.8 4.4 0.18 12.1 2.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF626) WD40 PF00400.27 ETO35153.1 - 1e-06 28.3 0.2 0.022 14.6 0.0 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat OmpH PF03938.9 ETO35153.1 - 0.013 15.4 4.9 0.02 14.8 3.4 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Cast PF10174.4 ETO35153.1 - 0.041 11.9 9.6 0.052 11.5 6.7 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone SBF2 PF12335.3 ETO35153.1 - 0.047 13.0 3.5 0.065 12.5 2.4 1.3 1 0 0 1 1 1 0 Myotubularin protein CENP-Q PF13094.1 ETO35153.1 - 0.73 9.8 11.6 5.9 6.8 8.0 2.2 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Atg14 PF10186.4 ETO35153.1 - 3.1 6.6 11.7 29 3.4 7.5 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ORF6C PF10552.4 ETO35153.1 - 3.1 7.5 14.7 1 9.1 5.6 2.6 1 1 1 2 2 2 0 ORF6C domain DUF2431 PF10354.4 ETO35154.1 - 0.011 15.7 0.1 0.014 15.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) Kelch_1 PF01344.20 ETO35155.1 - 3.9e-08 32.7 2.4 0.00025 20.5 0.2 4.3 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 ETO35155.1 - 4e-07 29.9 4.4 0.1 12.8 0.2 4.9 3 1 1 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO35155.1 - 8.1e-06 25.4 1.2 2.5 8.0 0.1 4.9 4 1 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO35155.1 - 0.00012 21.8 0.3 0.73 9.6 0.0 4.1 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO35155.1 - 0.0064 16.6 0.3 0.5 10.6 0.0 3.6 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO35155.1 - 0.035 14.0 1.3 0.9 9.5 0.2 3.6 5 0 0 5 5 5 0 Kelch motif Kelch_5 PF13854.1 ETO35156.1 - 0.00012 21.8 1.0 3.1 7.8 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO35156.1 - 0.0005 20.1 1.5 1.5 9.1 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO35156.1 - 0.034 13.9 0.2 0.4 10.4 0.1 2.6 2 0 0 2 2 2 0 Galactose oxidase, central domain Cupin_2 PF07883.6 ETO35157.1 - 2.1e-11 43.1 0.1 5.5e-11 41.7 0.1 1.7 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 ETO35157.1 - 3.5e-07 29.7 0.0 4.1e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Cupin FdtA PF05523.6 ETO35157.1 - 0.0018 17.7 0.1 0.0023 17.4 0.1 1.1 1 0 0 1 1 1 1 WxcM-like, C-terminal Cupin_8 PF13621.1 ETO35157.1 - 0.0041 16.6 0.8 0.014 14.9 0.5 1.6 1 1 1 2 2 2 1 Cupin-like domain Ectoine_synth PF06339.7 ETO35157.1 - 0.024 14.5 0.1 0.031 14.1 0.1 1.2 1 0 0 1 1 1 0 Ectoine synthase SUKH_5 PF14567.1 ETO35157.1 - 0.029 13.7 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall GPI PF06560.6 ETO35157.1 - 0.16 10.9 0.6 0.22 10.5 0.4 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) DUF1510 PF07423.6 ETO35159.1 - 0.00036 19.9 8.4 0.00057 19.3 5.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Mem_trans PF03547.13 ETO35159.1 - 0.00046 18.5 0.5 0.0006 18.2 0.3 1.4 1 0 0 1 1 1 1 Membrane transport protein Peptidase_S49_N PF08496.5 ETO35159.1 - 0.0022 17.7 4.8 0.0022 17.7 3.3 1.7 2 0 0 2 2 2 1 Peptidase family S49 N-terminal gpUL132 PF11359.3 ETO35159.1 - 0.015 14.6 0.2 0.023 14.0 0.1 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Shisa PF13908.1 ETO35159.1 - 0.12 12.5 0.8 0.25 11.4 0.6 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator MDFI PF15316.1 ETO35159.1 - 5.5 6.9 5.2 11 5.9 3.6 1.4 1 0 0 1 1 1 0 MyoD family inhibitor WD40 PF00400.27 ETO35160.1 - 0.00021 21.0 0.1 0.0076 16.1 0.0 2.4 2 0 0 2 2 2 1 WD domain, G-beta repeat Herpes_UL31 PF02718.9 ETO35160.1 - 0.36 9.4 6.7 0.44 9.2 4.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL31-like protein CTD_bind PF04818.8 ETO35162.1 - 0.079 13.2 1.3 0.14 12.3 0.2 1.9 2 0 0 2 2 2 0 RNA polymerase II-binding domain. 2OG-FeII_Oxy_2 PF13532.1 ETO35163.1 - 4.5e-18 65.7 0.0 5.3e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CPDase PF07823.6 ETO35164.1 - 2.5e-13 49.9 0.1 4.4e-13 49.1 0.1 1.4 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 ETO35164.1 - 0.0077 15.9 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Methyltransf_12 PF08242.7 ETO35164.1 - 0.0092 16.4 3.0 1.4 9.4 0.6 2.4 2 0 0 2 2 2 2 Methyltransferase domain CENP-B_dimeris PF09026.5 ETO35164.1 - 0.7 10.1 12.2 0.56 10.4 1.6 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Apis_Csd PF11671.3 ETO35164.1 - 4.6 7.0 14.3 5.3 6.8 1.5 2.4 2 0 0 2 2 2 0 Complementary sex determiner protein FAM176 PF14851.1 ETO35164.1 - 5.6 6.6 8.4 1.8 8.1 1.7 2.4 2 0 0 2 2 2 0 FAM176 family PBP1_TM PF14812.1 ETO35164.1 - 5.8 7.2 15.5 6.5 7.1 4.5 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FA_desaturase PF00487.19 ETO35165.1 - 2.5e-26 92.6 18.3 3.8e-26 92.0 12.7 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DLIC PF05783.6 ETO35166.1 - 0.0006 18.6 0.2 0.00098 17.9 0.0 1.4 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) ETRAMP PF09716.5 ETO35166.1 - 0.057 13.3 1.7 1.9 8.4 0.1 3.1 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) DUF3989 PF13150.1 ETO35166.1 - 2.7 7.5 5.6 1.9 7.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) WD40 PF00400.27 ETO35167.1 - 7.9e-32 107.9 9.5 1.4e-10 40.5 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO35167.1 - 1.7e-08 33.0 0.8 0.0078 14.3 0.0 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Ig_2 PF13895.1 ETO35167.1 - 0.058 13.5 0.3 0.22 11.6 0.2 1.8 2 0 0 2 2 2 0 Immunoglobulin domain TPR_12 PF13424.1 ETO35168.1 - 1.2e-135 441.6 36.0 9.3e-26 89.5 0.3 5.1 1 1 7 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.1 ETO35168.1 - 4.4e-49 163.0 0.0 1.5e-09 37.4 0.0 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETO35168.1 - 8e-48 158.1 50.7 1.1e-09 37.4 1.3 8.0 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_7 PF13176.1 ETO35168.1 - 8.8e-48 156.3 9.1 6.4e-07 28.6 0.0 7.4 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_2 PF07719.12 ETO35168.1 - 1.5e-45 149.4 30.9 2.6e-07 30.0 0.2 8.0 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_11 PF13414.1 ETO35168.1 - 5.3e-43 144.5 29.4 9.9e-15 53.9 2.0 4.5 3 2 0 4 4 4 4 TPR repeat TPR_8 PF13181.1 ETO35168.1 - 7.6e-37 122.3 54.4 1.1e-07 31.0 1.3 7.6 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_17 PF13431.1 ETO35168.1 - 1e-27 93.9 8.8 0.0015 18.5 0.1 8.0 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_14 PF13428.1 ETO35168.1 - 9.6e-15 53.7 0.0 0.87 10.4 0.0 7.3 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO35168.1 - 4.5e-14 51.8 13.7 0.012 16.0 0.5 7.7 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO35168.1 - 1.3e-13 51.2 0.0 0.032 14.9 0.0 6.6 4 1 3 7 7 7 5 Tetratricopeptide repeat Apc3 PF12895.2 ETO35168.1 - 1.2e-12 47.7 28.3 4.3e-05 23.5 2.4 5.1 1 1 4 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 ETO35168.1 - 7.3e-11 41.6 35.1 0.0047 16.7 0.1 7.6 8 0 0 8 8 8 4 Tetratricopeptide repeat PPR PF01535.15 ETO35168.1 - 4.9e-07 29.2 25.7 0.18 11.8 0.2 8.0 8 0 0 8 8 8 2 PPR repeat TPR_19 PF14559.1 ETO35168.1 - 1.6e-06 28.3 9.6 0.045 14.0 0.1 5.2 3 3 2 5 5 5 3 Tetratricopeptide repeat Mob_Pre PF01076.14 ETO35168.1 - 1.9e-06 27.6 14.0 0.015 14.9 0.1 3.9 2 1 2 4 4 4 3 Plasmid recombination enzyme Sel1 PF08238.7 ETO35168.1 - 1.3e-05 25.6 18.8 1.9 9.2 0.6 6.6 7 0 0 7 7 6 3 Sel1 repeat MIT PF04212.13 ETO35168.1 - 1.7e-05 24.5 23.6 0.43 10.5 0.2 6.7 7 0 0 7 7 7 3 MIT (microtubule interacting and transport) domain DUF2225 PF09986.4 ETO35168.1 - 0.00026 20.5 20.8 0.13 11.7 1.4 4.5 1 1 1 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) RPN7 PF10602.4 ETO35168.1 - 0.00099 18.5 20.0 0.17 11.2 1.9 5.2 1 1 3 4 4 4 2 26S proteasome subunit RPN7 Ten1_2 PF15490.1 ETO35168.1 - 0.0062 16.1 0.0 9 5.9 0.0 4.1 1 1 2 4 4 4 0 Telomere-capping, CST complex subunit DUF3568 PF12092.3 ETO35168.1 - 0.018 14.7 4.7 13 5.4 0.0 4.1 2 1 3 5 5 5 0 Protein of unknown function (DUF3568) DUF627 PF04781.7 ETO35168.1 - 0.026 14.1 15.9 4.1 7.0 0.0 6.0 1 1 3 5 5 5 0 Protein of unknown function (DUF627) HisG PF01634.13 ETO35168.1 - 0.04 13.4 2.2 5.9 6.4 0.0 4.1 1 1 4 5 5 5 0 ATP phosphoribosyltransferase SHNi-TPR PF10516.4 ETO35168.1 - 0.055 12.7 10.3 2.3 7.5 0.0 5.4 8 0 0 8 8 6 0 SHNi-TPR OEP PF02321.13 ETO35168.1 - 0.12 11.9 2.9 2.8 7.5 0.0 3.1 3 1 0 3 3 3 0 Outer membrane efflux protein TPR_21 PF09976.4 ETO35168.1 - 0.17 11.8 6.0 0.87 9.5 0.0 4.3 4 2 0 4 4 4 0 Tetratricopeptide repeat Ubiq-assoc PF09145.5 ETO35168.1 - 0.59 10.0 17.8 14 5.6 0.2 7.1 5 2 1 6 6 6 0 Ubiquitin-associated FATC PF02260.15 ETO35168.1 - 3.9 6.9 11.0 40 3.7 0.2 5.1 6 0 0 6 6 6 0 FATC domain VWA_N PF08399.6 ETO35170.1 - 0.03 14.9 1.8 0.039 14.5 1.2 1.3 1 0 0 1 1 1 0 VWA N-terminal VESA1_N PF12785.2 ETO35170.1 - 2.1 7.2 10.9 0.57 9.0 5.5 1.6 1 1 0 1 1 1 0 Variant erythrocyte surface antigen-1 Striatin PF08232.7 ETO35171.1 - 0.034 14.4 0.7 0.053 13.8 0.5 1.3 1 0 0 1 1 1 0 Striatin family WD40 PF00400.27 ETO35173.1 - 1.4e-68 224.4 20.5 2.5e-13 49.3 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO35173.1 - 7.7e-13 48.5 0.3 8e-06 25.6 0.0 3.2 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO35173.1 - 2.8e-09 35.6 2.4 4.1e-05 21.9 0.3 3.2 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO35173.1 - 2.7e-08 32.5 0.5 0.057 11.7 0.0 3.1 2 1 1 3 3 3 3 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO35173.1 - 3e-07 30.1 0.2 6.2e-05 22.5 0.1 2.7 1 1 2 3 3 3 2 PQQ-like domain Nbas_N PF15492.1 ETO35173.1 - 1.7e-06 27.3 2.4 0.74 8.8 0.0 4.9 3 1 2 5 5 5 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 ETO35173.1 - 1.1e-05 24.9 7.9 4.1 7.1 0.0 6.2 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Me-amine-dh_H PF06433.6 ETO35173.1 - 0.00027 19.6 0.1 0.087 11.4 0.0 3.1 1 1 2 4 4 4 1 Methylamine dehydrogenase heavy chain (MADH) IKI3 PF04762.7 ETO35173.1 - 0.003 15.4 0.4 0.058 11.2 0.0 2.2 1 1 1 2 2 2 1 IKI3 family Coatomer_WDAD PF04053.9 ETO35173.1 - 0.0038 16.0 4.7 0.067 11.9 0.6 2.9 1 1 2 3 3 3 2 Coatomer WD associated region DUF1513 PF07433.6 ETO35173.1 - 0.0049 15.8 0.3 3 6.6 0.0 3.1 1 1 1 3 3 3 2 Protein of unknown function (DUF1513) DUF1258 PF06869.7 ETO35173.1 - 0.0058 15.7 0.6 0.29 10.1 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1258) DPPIV_N PF00930.16 ETO35173.1 - 0.0097 14.5 0.0 5.7 5.4 0.0 3.3 1 1 2 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PQQ PF01011.16 ETO35173.1 - 0.015 14.8 0.0 66 3.3 0.0 5.1 7 0 0 7 7 7 0 PQQ enzyme repeat Hira PF07569.6 ETO35173.1 - 0.018 14.2 0.2 7.3 5.7 0.0 3.2 1 1 1 3 3 3 0 TUP1-like enhancer of split DUF2963 PF11178.3 ETO35173.1 - 0.03 13.7 8.0 1 8.8 0.0 5.2 5 2 0 5 5 4 0 Protein of unknown function (DUF2963) Proteasome_A_N PF10584.4 ETO35173.1 - 0.056 12.7 4.9 7.4 6.0 0.1 4.2 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Rav1p_C PF12234.3 ETO35173.1 - 0.25 9.4 2.9 1.9 6.5 0.1 2.8 1 1 1 3 3 3 0 RAVE protein 1 C terminal EF-hand_1 PF00036.27 ETO35176.1 - 3.3 7.2 6.0 0.4 10.0 1.0 2.0 2 0 0 2 2 2 0 EF hand CH PF00307.26 ETO35178.1 - 4.5e-09 36.3 0.0 8.7e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 Calponin homology (CH) domain Amidohydro_2 PF04909.9 ETO35179.1 - 1.1e-16 61.2 0.0 1.2e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase WD40 PF00400.27 ETO35180.1 - 1.7e-35 119.6 15.0 2.1e-13 49.5 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO35180.1 - 1.5e-06 26.6 0.9 0.042 12.0 0.1 2.7 1 1 2 3 3 3 2 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO35180.1 - 0.036 13.3 3.6 0.14 11.4 2.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4221) TPR_12 PF13424.1 ETO35181.1 - 1.9e-50 168.7 9.4 2.4e-16 59.3 1.3 4.2 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO35181.1 - 1.7e-28 96.9 22.3 5.1e-08 32.1 0.6 6.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO35181.1 - 8.7e-27 92.5 13.2 5.4e-12 45.1 3.1 4.4 2 1 3 5 5 5 4 TPR repeat TPR_7 PF13176.1 ETO35181.1 - 3e-26 89.1 0.4 3.8e-06 26.2 0.0 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO35181.1 - 2.1e-22 77.1 11.9 0.00019 21.0 0.3 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO35181.1 - 3.4e-21 73.3 23.6 0.00016 21.2 0.9 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO35181.1 - 2.1e-20 71.9 0.0 7.2e-05 22.5 0.0 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO35181.1 - 4.4e-07 30.3 0.0 4.1 8.1 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO35181.1 - 9.8e-07 28.5 6.6 0.0044 17.1 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO35181.1 - 2.9e-05 24.2 0.0 4.6 8.1 0.0 4.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO35181.1 - 7.2e-05 22.9 4.4 0.24 11.9 0.2 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat Fer4_12 PF13353.1 ETO35181.1 - 0.00024 21.2 4.2 0.022 14.9 0.5 2.8 1 1 1 2 2 2 2 4Fe-4S single cluster domain MIT PF04212.13 ETO35181.1 - 0.0017 18.2 12.5 0.05 13.4 0.4 4.5 5 0 0 5 5 5 2 MIT (microtubule interacting and transport) domain PPR PF01535.15 ETO35181.1 - 0.62 10.1 11.2 7 6.8 0.1 5.4 5 0 0 5 5 4 0 PPR repeat PA PF02225.17 ETO35182.1 - 0.00028 20.5 0.0 0.00044 19.8 0.0 1.3 1 0 0 1 1 1 1 PA domain DUF3922 PF13059.1 ETO35182.1 - 0.093 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3992) zf-C3HC4_2 PF13923.1 ETO35183.1 - 0.0023 17.9 3.7 0.021 14.8 2.6 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Cys_knot PF00007.17 ETO35183.1 - 0.0073 16.3 4.6 0.0092 16.0 3.2 1.3 1 0 0 1 1 1 1 Cystine-knot domain Hydrolase_6 PF13344.1 ETO35183.1 - 0.096 12.5 0.2 9.1 6.2 0.0 2.1 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase WD40 PF00400.27 ETO35184.1 - 2.5e-18 65.1 10.3 2e-06 27.4 0.2 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO35184.1 - 0.00012 20.3 0.1 0.00055 18.1 0.0 1.9 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Prok-RING_2 PF14445.1 ETO35184.1 - 0.088 12.7 0.7 0.088 12.7 0.5 1.9 2 1 0 2 2 2 0 Prokaryotic RING finger family 2 NinE PF05322.6 ETO35184.1 - 0.17 11.6 2.5 0.49 10.1 0.1 2.4 2 1 0 2 2 2 0 NINE Protein WD40 PF00400.27 ETO35185.1 - 1.6e-137 443.0 51.0 2.1e-12 46.4 0.4 16.3 16 0 0 16 16 16 16 WD domain, G-beta repeat Pentapeptide PF00805.17 ETO35185.1 - 1.2e-05 24.4 0.3 2.5e-05 23.3 0.2 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO35185.1 - 5.1e-05 23.0 0.3 0.00014 21.5 0.2 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Mid2 PF04478.7 ETO35185.1 - 0.00054 19.3 21.4 4.3 6.7 0.2 8.6 4 4 5 9 9 9 3 Mid2 like cell wall stress sensor Pentapeptide_3 PF13576.1 ETO35185.1 - 0.00069 19.4 0.2 0.0026 17.6 0.1 2.0 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) PQQ_2 PF13360.1 ETO35185.1 - 0.003 17.0 5.8 1.2 8.5 0.5 4.0 3 2 0 3 3 3 2 PQQ-like domain PD40 PF07676.7 ETO35185.1 - 0.0048 16.5 9.8 12 5.7 0.0 6.9 8 0 0 8 8 8 1 WD40-like Beta Propeller Repeat Corona_NS8 PF12093.3 ETO35185.1 - 0.088 13.1 0.0 5.5 7.3 0.0 3.1 2 0 0 2 2 2 0 Coronavirus NS8 protein Kelch_6 PF13964.1 ETO35186.1 - 0.00052 20.0 5.2 0.092 12.9 1.0 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 ETO35186.1 - 0.0028 17.3 4.3 0.84 9.4 0.4 2.5 2 0 0 2 2 2 2 Galactose oxidase, central domain LIM PF00412.17 ETO35186.1 - 0.12 12.4 1.7 0.33 11.0 0.5 2.2 2 0 0 2 2 2 0 LIM domain Kelch_3 PF13415.1 ETO35186.1 - 0.28 11.3 1.1 1.3 9.2 0.2 2.4 2 1 0 2 2 2 0 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO35187.1 - 1.5e-05 24.6 8.0 0.00044 19.9 0.1 4.2 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO35187.1 - 3.1e-05 23.9 9.6 0.073 13.2 0.1 4.5 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 ETO35187.1 - 0.00019 21.4 3.9 0.0038 17.3 0.0 3.5 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO35187.1 - 0.00045 19.6 9.0 0.0095 15.4 0.1 3.5 3 1 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 ETO35187.1 - 0.014 15.1 0.1 0.014 15.1 0.1 3.6 4 0 0 4 4 4 0 Kelch motif DUF1236 PF06823.7 ETO35187.1 - 0.034 13.8 0.0 0.083 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1236) Kelch_5 PF13854.1 ETO35187.1 - 0.81 9.7 7.5 1.4 8.9 0.2 2.9 3 0 0 3 3 3 0 Kelch motif Peptidase_M23 PF01551.17 ETO35188.1 - 3.4e-16 59.0 0.7 9e-16 57.7 0.1 1.9 2 0 0 2 2 2 1 Peptidase family M23 RRM_1 PF00076.17 ETO35188.1 - 0.011 15.3 0.7 0.025 14.2 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RnfC_N PF13375.1 ETO35188.1 - 0.056 13.1 0.0 1.4 8.6 0.0 2.6 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain SR-25 PF10500.4 ETO35188.1 - 4.2 6.7 23.7 1 8.7 13.9 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein fn3 PF00041.16 ETO35189.1 - 0.025 14.7 0.5 0.14 12.3 0.1 2.3 2 1 0 2 2 2 0 Fibronectin type III domain DUF4246 PF14033.1 ETO35191.1 - 0.0037 15.9 1.2 0.0045 15.6 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) NOA36 PF06524.7 ETO35191.1 - 0.09 12.0 7.4 0.13 11.5 5.2 1.2 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 ETO35191.1 - 0.19 9.7 8.9 0.25 9.3 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.11 ETO35191.1 - 1 8.3 5.3 1.8 7.5 3.7 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit UPF0560 PF10577.4 ETO35191.1 - 2.7 6.1 7.2 4.4 5.4 5.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF2457 PF10446.4 ETO35191.1 - 2.9 6.5 16.1 3.9 6.0 11.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 ETO35191.1 - 3.6 7.0 11.1 5.8 6.4 7.7 1.2 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 ETO35191.1 - 5.1 7.4 13.5 10 6.4 9.3 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sporozoite_P67 PF05642.6 ETO35191.1 - 6.2 4.5 6.5 8.1 4.1 4.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Borrelia_P83 PF05262.6 ETO35192.1 - 0.0084 14.4 4.9 0.0099 14.1 3.4 1.0 1 0 0 1 1 1 1 Borrelia P83/100 protein Tir_receptor_C PF07489.6 ETO35192.1 - 0.032 14.0 6.6 0.046 13.4 4.6 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus SR-25 PF10500.4 ETO35192.1 - 0.085 12.3 7.7 0.11 11.9 5.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ephrin_lbd PF01404.14 ETO35192.1 - 0.14 11.9 1.9 0.21 11.3 1.3 1.3 1 0 0 1 1 1 0 Ephrin receptor ligand binding domain DUF966 PF06136.8 ETO35192.1 - 3.7 6.8 9.9 4.5 6.5 6.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Pneumo_att_G PF05539.6 ETO35192.1 - 8.8 5.5 12.5 11 5.2 8.7 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G NAM PF02365.10 ETO35193.1 - 0.19 11.8 2.7 0.15 12.2 0.4 1.9 2 1 0 2 2 2 0 No apical meristem (NAM) protein HMGL-like PF00682.14 ETO35194.1 - 1e-31 110.4 0.6 1.3e-31 110.0 0.4 1.1 1 0 0 1 1 1 1 HMGL-like PUB PF09409.5 ETO35196.1 - 0.025 14.3 2.1 0.084 12.6 0.3 2.6 2 1 0 2 2 2 0 PUB domain DUF2650 PF10853.3 ETO35196.1 - 0.099 12.1 5.5 0.37 10.2 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2650) WD40 PF00400.27 ETO35197.1 - 1.4e-37 126.2 7.3 2.9e-13 49.1 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO35197.1 - 9.9e-07 28.6 9.7 0.0015 18.6 0.4 5.7 7 0 0 7 7 7 2 Kelch motif PD40 PF07676.7 ETO35197.1 - 1e-05 25.0 1.2 1.5 8.6 0.1 3.5 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Kelch_2 PF07646.10 ETO35197.1 - 5.9e-05 22.6 1.8 0.077 12.7 0.2 3.9 3 0 0 3 3 3 1 Kelch motif Cytochrom_D1 PF02239.11 ETO35197.1 - 0.0005 18.4 0.1 0.0012 17.2 0.1 1.7 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nup160 PF11715.3 ETO35197.1 - 0.00083 17.6 1.6 0.16 10.0 0.1 2.6 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Kelch_4 PF13418.1 ETO35197.1 - 0.0021 17.8 1.6 0.058 13.1 0.0 3.2 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO35197.1 - 0.0024 17.3 4.5 0.22 11.0 0.5 3.6 3 0 0 3 3 3 1 Kelch motif Nucleoporin_N PF08801.6 ETO35197.1 - 0.004 15.9 1.5 0.17 10.6 0.2 2.8 1 1 2 3 3 3 2 Nup133 N terminal like Kelch_5 PF13854.1 ETO35197.1 - 0.0061 16.4 8.4 0.45 10.5 0.4 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO35197.1 - 0.021 14.9 0.2 0.72 10.0 0.0 3.1 3 0 0 3 3 3 0 Galactose oxidase, central domain DPPIV_N PF00930.16 ETO35197.1 - 0.025 13.1 0.1 0.5 8.8 0.0 2.6 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PQQ PF01011.16 ETO35197.1 - 0.61 9.7 4.7 0.27 10.8 0.1 2.6 3 0 0 3 3 3 0 PQQ enzyme repeat Proteasome_A_N PF10584.4 ETO35197.1 - 0.72 9.2 3.5 41 3.6 0.4 3.3 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Sulfotransfer_2 PF03567.9 ETO35198.1 - 8.1e-12 45.3 1.2 1.4e-11 44.5 0.8 1.3 1 0 0 1 1 1 1 Sulfotransferase family Lzipper-MIP1 PF14389.1 ETO35199.1 - 1.3e-06 28.3 17.4 0.00086 19.3 2.9 3.9 3 1 0 3 3 3 2 Leucine-zipper of ternary complex factor MIP1 Prp19 PF08606.6 ETO35199.1 - 0.0047 16.6 1.3 0.48 10.1 0.1 3.2 2 1 0 2 2 2 1 Prp19/Pso4-like CCDC92 PF14916.1 ETO35199.1 - 0.045 13.3 0.8 0.045 13.3 0.6 3.2 3 1 0 3 3 3 0 Coiled-coil domain of unknown function T3SS_LEE_assoc PF13327.1 ETO35199.1 - 0.13 11.7 2.1 0.15 11.6 0.3 2.0 2 1 0 2 2 2 0 Type III secretion system subunit DUF1192 PF06698.6 ETO35199.1 - 0.24 11.2 2.2 5.1 6.9 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Pox_A_type_inc PF04508.7 ETO35199.1 - 1.4 8.8 12.3 5.8 6.9 0.0 5.3 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat FlaC_arch PF05377.6 ETO35199.1 - 2 8.3 14.8 2.8 7.9 0.3 4.5 3 1 2 5 5 5 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.3 ETO35199.1 - 2.1 8.2 36.9 0.15 11.8 1.5 5.2 4 1 1 5 5 5 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 ETO35199.1 - 2.9 7.4 31.7 0.65 9.5 6.7 3.1 2 1 1 3 3 3 0 IncA protein TPR_MLP1_2 PF07926.7 ETO35199.1 - 3.5 7.3 32.3 0.026 14.2 4.4 3.8 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Tup_N PF08581.5 ETO35199.1 - 4.6 7.5 19.9 6.4 7.0 4.6 3.8 3 1 0 3 3 2 0 Tup N-terminal TSC22 PF01166.13 ETO35199.1 - 4.8 7.2 13.9 0.78 9.7 0.9 4.1 2 1 1 3 3 3 0 TSC-22/dip/bun family LAGLIDADG_1 PF00961.14 ETO35199.1 - 5.5 7.6 12.4 19 5.8 2.9 3.1 1 1 0 2 2 2 0 LAGLIDADG endonuclease DUF948 PF06103.6 ETO35199.1 - 8.7 6.2 19.5 0.26 11.1 1.0 4.1 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) BMFP PF04380.8 ETO35199.1 - 9.4 6.4 17.2 1.4 9.1 1.3 4.7 4 2 1 5 5 4 0 Membrane fusogenic activity DASH_Dam1 PF08653.5 ETO35199.1 - 9.9 6.0 10.8 32 4.3 0.1 3.8 4 1 0 4 4 3 0 DASH complex subunit Dam1 Spore_II_R PF09551.5 ETO35200.1 - 0.017 15.1 6.5 0.9 9.5 0.6 2.5 2 0 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) PQ-loop PF04193.9 ETO35201.1 - 2.7e-26 90.8 20.0 1.3e-15 56.6 3.4 3.2 3 0 0 3 3 3 2 PQ loop repeat Gly-zipper_Omp PF13488.1 ETO35202.1 - 9.2e-06 25.2 80.4 1e+03 -0.6 21.9 6.8 1 1 1 2 2 2 0 Glycine zipper Gly-zipper_YMGG PF13441.1 ETO35202.1 - 0.0042 16.5 65.3 0.63 9.5 8.9 6.1 1 1 4 5 5 5 4 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.10 ETO35202.1 - 0.024 14.2 19.9 0.024 14.2 13.8 6.6 2 1 3 5 5 5 0 Glycine zipper 2TM domain TraT PF05818.7 ETO35202.1 - 0.22 10.9 35.2 1.3 8.3 0.3 4.3 1 1 2 3 3 3 0 Enterobacterial TraT complement resistance protein Bacteriocin_IIc PF10439.4 ETO35202.1 - 6.5 6.9 72.5 1.3 9.1 13.6 6.3 1 1 2 3 3 3 0 Bacteriocin class II with double-glycine leader peptide PB1 PF00564.19 ETO35203.1 - 0.0026 17.4 0.0 0.0094 15.5 0.0 1.8 2 0 0 2 2 2 1 PB1 domain MIR PF02815.14 ETO35203.1 - 0.016 14.7 0.2 0.042 13.3 0.0 1.5 1 1 0 1 1 1 0 MIR domain Ins145_P3_rec PF08709.6 ETO35203.1 - 0.06 12.3 0.4 5.7 5.8 0.0 2.3 1 1 1 2 2 2 0 Inositol 1,4,5-trisphosphate/ryanodine receptor Pkinase PF00069.20 ETO35205.1 - 1.1e-49 168.9 1.4 3.5e-48 164.0 0.2 2.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO35205.1 - 1.1e-29 103.3 0.1 8.5e-29 100.4 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO35205.1 - 3.7e-07 29.3 0.0 6.3e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PIP49_C PF12260.3 ETO35205.1 - 0.035 13.5 0.0 0.083 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 PPR_2 PF13041.1 ETO35207.1 - 1.3e-07 31.4 2.5 1.9e-05 24.5 0.0 3.2 1 1 2 3 3 3 2 PPR repeat family PPR_3 PF13812.1 ETO35207.1 - 1.9e-06 27.6 0.7 5.1 7.6 0.0 4.6 4 0 0 4 4 4 3 Pentatricopeptide repeat domain PPR PF01535.15 ETO35207.1 - 2e-05 24.2 6.9 0.19 11.7 0.2 4.1 4 0 0 4 4 4 3 PPR repeat DUF3581 PF12119.3 ETO35207.1 - 0.019 14.2 0.6 0.053 12.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3581) RST PF12174.3 ETO35209.1 - 0.023 14.5 0.1 0.041 13.6 0.1 1.4 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain WD40 PF00400.27 ETO35210.1 - 1e-36 123.4 15.7 5.9e-11 41.8 0.4 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO35210.1 - 3.1e-08 32.2 5.2 0.00022 19.4 0.2 3.7 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO35210.1 - 0.00026 19.8 3.4 0.3 9.7 1.3 3.2 1 1 1 2 2 2 2 Nup133 N terminal like Kelch_6 PF13964.1 ETO35210.1 - 5.5 7.3 8.4 4.9 7.5 0.2 3.7 3 1 1 4 4 4 0 Kelch motif TPR_12 PF13424.1 ETO35211.1 - 3.3e-91 299.2 4.9 1.4e-26 92.2 0.1 5.1 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.23 ETO35211.1 - 3.1e-58 191.1 42.7 7.9e-10 37.9 1.1 9.2 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_11 PF13414.1 ETO35211.1 - 1e-56 188.4 17.2 8.6e-17 60.5 0.4 6.0 4 2 2 6 6 6 5 TPR repeat TPR_7 PF13176.1 ETO35211.1 - 5.5e-54 175.7 8.1 1.5e-08 33.8 0.1 9.0 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.12 ETO35211.1 - 9.7e-48 156.2 30.1 2.3e-08 33.3 0.2 9.2 8 1 1 9 9 9 8 Tetratricopeptide repeat TPR_10 PF13374.1 ETO35211.1 - 1.7e-47 158.0 0.0 9.4e-08 31.7 0.0 8.4 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETO35211.1 - 1.4e-44 146.5 51.4 1.9e-08 33.5 0.2 8.8 8 1 1 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.1 ETO35211.1 - 9.5e-21 73.9 0.0 0.00039 21.0 0.0 6.3 3 1 3 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 ETO35211.1 - 3e-20 70.6 21.1 0.0061 16.6 0.2 9.6 10 1 0 10 10 8 5 Tetratricopeptide repeat TPR_6 PF13174.1 ETO35211.1 - 2.4e-18 65.2 8.8 0.22 12.0 0.0 8.3 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 ETO35211.1 - 2.8e-18 64.7 0.0 0.039 14.6 0.0 7.6 5 2 3 8 8 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 ETO35211.1 - 2e-11 44.0 0.4 0.024 14.9 0.0 4.6 3 1 2 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 ETO35211.1 - 2.3e-09 37.2 22.8 0.0039 17.2 4.4 5.0 1 1 4 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 ETO35211.1 - 4.4e-08 32.9 30.6 0.77 9.6 0.2 7.8 8 1 1 9 9 7 5 MIT (microtubule interacting and transport) domain Sel1 PF08238.7 ETO35211.1 - 7.1e-08 32.8 15.6 1.1 10.0 0.1 7.5 8 0 0 8 8 7 2 Sel1 repeat PPR PF01535.15 ETO35211.1 - 1.9e-07 30.5 18.8 0.26 11.3 0.0 7.3 8 0 0 8 8 7 2 PPR repeat TPR_3 PF07720.7 ETO35211.1 - 2.7e-07 30.2 22.8 1.5 8.6 0.2 7.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETO35211.1 - 2.8e-06 27.0 0.0 0.22 11.4 0.0 4.3 1 1 4 5 5 5 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO35211.1 - 1.3e-05 24.3 4.6 3.3 7.0 0.0 6.2 6 0 0 6 6 6 1 SHNi-TPR DUF627 PF04781.7 ETO35211.1 - 2.9e-05 23.6 5.8 8.2 6.0 0.1 5.3 3 1 1 5 5 5 0 Protein of unknown function (DUF627) Ten1_2 PF15490.1 ETO35211.1 - 0.00071 19.1 0.0 15 5.1 0.0 4.9 2 1 3 5 5 5 0 Telomere-capping, CST complex subunit FATC PF02260.15 ETO35211.1 - 0.033 13.6 0.1 16 5.0 0.0 3.3 3 0 0 3 3 3 0 FATC domain HisG PF01634.13 ETO35211.1 - 0.037 13.6 1.2 6.5 6.3 0.1 3.1 1 1 2 3 3 3 0 ATP phosphoribosyltransferase DUF3775 PF12616.3 ETO35211.1 - 0.094 12.5 0.1 4.5 7.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3775) RPN7 PF10602.4 ETO35211.1 - 0.094 12.0 18.9 1.6 8.0 0.1 5.9 3 2 3 6 6 6 0 26S proteasome subunit RPN7 MerR_1 PF13411.1 ETO35211.1 - 0.16 11.7 8.1 1.1 9.0 0.5 4.0 4 0 0 4 4 4 0 MerR HTH family regulatory protein Clathrin PF00637.15 ETO35211.1 - 0.25 10.9 18.9 11 5.6 0.3 5.8 3 2 0 5 5 5 0 Region in Clathrin and VPS Sec5 PF15469.1 ETO35211.1 - 2.7 7.6 18.4 89 2.7 0.1 4.4 2 2 0 2 2 2 0 Exocyst complex component Sec5 Ras PF00071.17 ETO35213.1 - 5.9e-48 162.3 1.0 8.6e-48 161.7 0.7 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO35213.1 - 1.4e-12 48.1 0.0 3.3e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO35213.1 - 1.7e-10 40.4 0.2 2.3e-10 40.0 0.2 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO35213.1 - 0.0017 17.8 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Phage_integrase PF00589.17 ETO35213.1 - 0.0089 15.7 0.3 0.0089 15.7 0.2 1.4 2 0 0 2 2 2 1 Phage integrase family Gtr1_RagA PF04670.7 ETO35213.1 - 0.0098 15.0 0.1 0.039 13.0 0.1 2.0 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region zf-RING_3 PF14369.1 ETO35214.1 - 0.045 13.7 0.1 0.09 12.7 0.0 1.5 1 0 0 1 1 1 0 zinc-finger Glycoamylase PF10091.4 ETO35218.1 - 0.012 14.6 0.1 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Putative glucoamylase RelA_SpoT PF04607.12 ETO35221.1 - 0.028 14.4 0.7 0.096 12.7 0.1 2.2 2 0 0 2 2 2 0 Region found in RelA / SpoT proteins DUF3853 PF12964.2 ETO35221.1 - 0.087 12.6 0.6 0.33 10.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3853) Peptidase_C14 PF00656.17 ETO35222.1 - 3.7e-12 46.4 0.3 9.2e-12 45.1 0.2 1.5 1 1 0 1 1 1 1 Caspase domain Copper-bind PF00127.15 ETO35222.1 - 0.091 13.0 0.2 8.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Copper binding proteins, plastocyanin/azurin family AAA_assoc_C PF09821.4 ETO35222.1 - 0.17 12.1 1.8 0.41 10.9 0.5 2.1 2 0 0 2 2 2 0 C-terminal AAA-associated domain DUF4033 PF13225.1 ETO35223.1 - 0.00034 20.1 7.7 0.066 12.8 0.1 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF4033) NifW PF03206.9 ETO35224.1 - 0.011 15.8 0.2 4.1 7.5 0.0 3.4 3 0 0 3 3 3 0 Nitrogen fixation protein NifW DUF1500 PF07389.7 ETO35225.1 - 0.021 14.8 2.5 0.093 12.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1500) DUF2140 PF09911.4 ETO35225.1 - 0.054 12.6 0.2 0.12 11.5 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) HDAC4_Gln PF12203.3 ETO35225.1 - 0.65 9.9 5.4 1.8 8.5 3.7 1.7 1 0 0 1 1 1 0 Glutamine rich N terminal domain of histone deacetylase 4 LAGLIDADG_1 PF00961.14 ETO35225.1 - 1.5 9.3 4.6 1.5 9.4 0.4 2.8 3 1 0 3 3 3 0 LAGLIDADG endonuclease zf-C3HC4_2 PF13923.1 ETO35226.1 - 0.0015 18.5 2.7 0.011 15.7 1.9 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO35226.1 - 0.0021 17.8 2.4 0.0049 16.6 1.7 1.6 1 1 0 1 1 1 1 Ring finger domain Cys_knot PF00007.17 ETO35226.1 - 0.029 14.4 5.4 0.032 14.2 3.7 1.2 1 0 0 1 1 1 0 Cystine-knot domain WD40 PF00400.27 ETO35227.1 - 7.9e-23 79.4 5.4 5.9e-10 38.6 0.1 3.6 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO35227.1 - 0.0029 15.8 0.0 1.4 6.9 0.0 2.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Bet_v_1 PF00407.14 ETO35227.1 - 0.024 14.2 2.9 7.5 6.1 0.0 3.5 2 1 2 4 4 4 0 Pathogenesis-related protein Bet v I family WD40 PF00400.27 ETO35228.1 - 5.4e-40 133.8 14.6 3.8e-10 39.2 0.3 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO35228.1 - 1.4e-10 39.9 0.0 0.0021 16.2 0.0 3.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO35228.1 - 0.0096 15.6 0.7 8.2 6.2 0.0 4.2 2 1 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.27 ETO35230.1 - 2.5e-36 122.2 9.9 2.9e-12 45.9 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO35230.1 - 1.7e-09 36.3 1.4 0.00063 18.0 0.1 3.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 AAA_30 PF13604.1 ETO35232.1 - 3.5e-42 144.2 0.6 3.5e-42 144.2 0.4 1.5 2 0 0 2 2 2 1 AAA domain TrwC PF08751.6 ETO35232.1 - 4.3e-11 42.7 0.7 1e-10 41.5 0.5 1.6 1 0 0 1 1 1 1 TrwC relaxase AAA_11 PF13086.1 ETO35232.1 - 5e-05 22.9 0.7 0.094 12.2 0.0 2.8 2 1 1 3 3 3 2 AAA domain ABC_tran PF00005.22 ETO35232.1 - 5.1e-05 23.5 4.1 0.059 13.6 0.2 2.7 1 1 1 2 2 2 2 ABC transporter AAA_22 PF13401.1 ETO35232.1 - 6.5e-05 23.0 0.2 0.00016 21.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETO35232.1 - 0.00024 20.8 0.5 0.0005 19.7 0.4 1.6 1 0 0 1 1 1 1 Part of AAA domain PhoH PF02562.11 ETO35232.1 - 0.009 15.2 2.2 2.3 7.3 0.0 2.4 1 1 1 2 2 2 2 PhoH-like protein NTPase_1 PF03266.10 ETO35232.1 - 0.015 15.0 1.6 1.1 8.9 0.2 2.5 2 0 0 2 2 2 0 NTPase AAA_29 PF13555.1 ETO35232.1 - 0.12 11.9 0.5 4 7.0 0.2 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_18 PF13238.1 ETO35232.1 - 0.13 12.5 1.3 0.43 10.8 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 ETO35232.1 - 0.13 12.4 1.3 0.42 10.8 0.9 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 ETO35232.1 - 0.19 12.5 2.2 1.6 9.5 0.0 3.0 3 1 0 3 3 3 0 AAA domain TPR_12 PF13424.1 ETO35233.1 - 2.1e-40 136.5 1.5 4.4e-25 87.4 0.1 3.4 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO35233.1 - 1.2e-33 113.9 0.2 1.4e-09 37.5 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO35233.1 - 1.3e-22 78.4 11.7 1.4e-07 30.7 0.1 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO35233.1 - 1.4e-22 77.6 1.6 1e-06 28.0 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO35233.1 - 9.2e-20 70.0 6.6 7.7e-11 41.4 0.4 3.7 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.1 ETO35233.1 - 8.4e-16 56.5 18.8 8.5e-07 28.3 0.7 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO35233.1 - 1.8e-13 49.3 10.5 5.4e-05 22.7 0.1 5.3 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO35233.1 - 7.3e-09 35.1 7.5 0.12 12.6 0.1 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO35233.1 - 1.3e-06 28.8 0.6 0.0036 17.9 0.0 4.0 2 1 2 4 4 3 3 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO35233.1 - 6.4e-06 25.3 0.6 0.17 11.1 0.0 3.9 3 0 0 3 3 3 1 SHNi-TPR Lipase_3 PF01764.20 ETO35233.1 - 1.3e-05 24.7 0.1 4.7e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) AAA_22 PF13401.1 ETO35233.1 - 2.4e-05 24.4 0.2 0.00026 21.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF2974 PF11187.3 ETO35233.1 - 8.3e-05 22.0 0.0 0.00022 20.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) NB-ARC PF00931.17 ETO35233.1 - 0.00056 18.8 0.0 0.0013 17.6 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_14 PF13428.1 ETO35233.1 - 0.00073 19.9 0.0 21 6.1 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat ABC_tran PF00005.22 ETO35233.1 - 0.0034 17.6 0.0 0.014 15.7 0.0 2.1 1 0 0 1 1 1 1 ABC transporter TPR_6 PF13174.1 ETO35233.1 - 0.015 15.7 6.7 1.4 9.5 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat GST_C_3 PF14497.1 ETO35233.1 - 0.022 15.2 0.0 32 5.0 0.0 4.1 2 1 2 4 4 3 0 Glutathione S-transferase, C-terminal domain MIT PF04212.13 ETO35233.1 - 0.022 14.6 4.4 0.51 10.2 0.1 3.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain IstB_IS21 PF01695.12 ETO35233.1 - 0.064 12.6 0.1 0.3 10.4 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein KaiC PF06745.8 ETO35233.1 - 0.064 12.3 0.1 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 KaiC HCR PF07111.7 ETO35233.1 - 0.087 10.8 0.1 0.13 10.2 0.0 1.1 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) AAA_33 PF13671.1 ETO35233.1 - 0.18 11.7 0.0 0.47 10.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETO35233.1 - 0.18 11.7 0.0 3.1 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Fib_alpha PF08702.5 ETO35233.1 - 0.56 10.3 7.4 0.13 12.4 1.4 2.8 3 0 0 3 3 1 0 Fibrinogen alpha/beta chain family Fis1_TPR_C PF14853.1 ETO35233.1 - 1.2 9.0 11.9 28 4.6 0.0 5.4 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat WD40 PF00400.27 ETO35234.1 - 1.3e-57 189.7 25.5 2.2e-10 39.9 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO35234.1 - 5e-08 31.5 7.8 0.003 15.7 0.1 5.4 1 1 3 5 5 5 4 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO35234.1 - 0.0028 17.0 3.2 0.004 16.5 1.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4221) CsgF PF10614.4 ETO35234.1 - 0.038 13.9 0.0 0.087 12.8 0.0 1.6 1 0 0 1 1 1 0 Type VIII secretion system (T8SS), CsgF protein Epimerase PF01370.16 ETO35235.1 - 1.9e-24 86.4 0.0 3.5e-24 85.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETO35235.1 - 3.5e-22 78.4 0.0 5.1e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 ETO35235.1 - 7.4e-16 58.6 0.0 1.3e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 ETO35235.1 - 1e-11 44.2 0.0 1.1e-10 40.8 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 ETO35235.1 - 4.9e-08 32.5 0.0 1.5e-07 30.9 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 ETO35235.1 - 3.9e-07 30.1 0.0 1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETO35235.1 - 7.7e-05 22.4 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 ETO35235.1 - 0.00019 20.4 0.0 0.00038 19.4 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 ETO35235.1 - 0.003 16.4 0.0 0.0052 15.7 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain DUF4408 PF14364.1 ETO35238.1 - 1.2 8.7 7.2 0.42 10.2 2.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4408) PXB PF12828.2 ETO35240.1 - 0.0067 16.0 1.1 3.5 7.2 0.0 2.5 2 0 0 2 2 2 2 PX-associated SecA_DEAD PF07517.9 ETO35240.1 - 0.063 12.5 0.1 0.2 10.8 0.0 1.8 1 1 0 1 1 1 0 SecA DEAD-like domain DUF4566 PF15130.1 ETO35241.1 - 0.013 14.7 1.3 0.016 14.4 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4566) Protocadherin PF08374.6 ETO35241.1 - 2.1 7.9 9.0 0.61 9.6 4.6 1.4 1 1 0 1 1 1 0 Protocadherin SR-25 PF10500.4 ETO35241.1 - 2.8 7.3 7.3 3.7 6.9 5.1 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Kelch_6 PF13964.1 ETO35242.1 - 1.1e-08 34.8 2.5 7.2e-05 22.7 0.2 4.6 3 1 1 4 4 4 1 Kelch motif Kelch_2 PF07646.10 ETO35242.1 - 3.3e-08 32.9 1.3 0.011 15.5 0.3 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO35242.1 - 2.9e-06 26.9 0.4 0.021 14.5 0.0 3.4 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO35242.1 - 9.8e-06 25.0 5.0 0.03 13.8 0.3 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO35242.1 - 7.3e-05 22.6 3.9 0.014 15.3 0.4 4.1 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.1 ETO35242.1 - 0.00015 21.7 0.2 0.032 14.3 0.0 3.8 5 0 0 5 5 5 1 Galactose oxidase, central domain PTEN_C2 PF10409.4 ETO35242.1 - 0.027 14.1 0.4 0.5 10.0 0.0 2.4 2 0 0 2 2 2 0 C2 domain of PTEN tumour-suppressor protein PH PF00169.24 ETO35243.1 - 0.11 12.6 3.2 0.49 10.6 2.2 2.4 1 1 0 1 1 1 0 PH domain Adaptin_binding PF10199.4 ETO35244.1 - 0.12 12.6 9.9 0.18 12.0 6.9 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Arena_glycoprot PF00798.13 ETO35244.1 - 0.49 8.7 6.5 0.59 8.4 4.5 1.1 1 0 0 1 1 1 0 Arenavirus glycoprotein DDHD PF02862.12 ETO35244.1 - 0.9 9.2 8.8 1.1 8.9 6.1 1.1 1 0 0 1 1 1 0 DDHD domain Med15 PF09606.5 ETO35244.1 - 1.1 7.4 39.4 1.3 7.0 27.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4557 PF15101.1 ETO35244.1 - 1.1 9.0 16.4 1.7 8.4 11.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) PAT1 PF09770.4 ETO35244.1 - 1.7 6.7 23.7 2.1 6.5 16.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FixO PF02433.10 ETO35244.1 - 4 6.7 7.6 5.3 6.3 5.3 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO Glyco_hydro_2 PF00703.16 ETO35244.1 - 6.5 7.2 7.4 8.8 6.8 4.8 1.5 1 1 0 1 1 1 0 Glycosyl hydrolases family 2 Neur_chan_memb PF02932.11 ETO35244.1 - 7.7 6.3 6.9 9.4 6.0 4.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FH2 PF02181.18 ETO35246.1 - 5.7e-06 25.4 0.1 5.7e-06 25.4 0.1 1.9 1 1 0 2 2 2 1 Formin Homology 2 Domain CorA PF01544.13 ETO35246.1 - 0.037 13.0 0.6 0.044 12.8 0.4 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein CHAD PF05235.9 ETO35246.1 - 0.05 13.1 0.6 0.069 12.7 0.4 1.3 1 0 0 1 1 1 0 CHAD domain SLX9 PF15341.1 ETO35246.1 - 0.053 13.9 7.0 0.076 13.4 4.8 1.3 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 DUF3047 PF11249.3 ETO35246.1 - 0.08 12.3 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3047) DivIC PF04977.10 ETO35246.1 - 1.1 8.7 5.4 4.1 6.9 0.1 2.4 2 0 0 2 2 2 0 Septum formation initiator Rho_Binding PF08912.6 ETO35246.1 - 1.6 9.0 11.2 4.2 7.7 0.1 2.6 1 1 2 3 3 3 0 Rho Binding DUF342 PF03961.8 ETO35246.1 - 1.9 6.8 5.6 0.8 8.0 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF342) FlxA PF14282.1 ETO35246.1 - 8.1 6.4 13.3 5.8 6.9 7.0 2.3 2 1 0 2 2 2 0 FlxA-like protein FH2 PF02181.18 ETO35247.1 - 1.3e-69 234.8 5.7 1.3e-69 234.8 4.0 2.3 2 0 0 2 2 2 1 Formin Homology 2 Domain DUF2360 PF10152.4 ETO35247.1 - 1.6e-15 57.6 18.0 9.6e-09 35.6 3.4 3.3 4 1 0 4 4 4 2 Predicted coiled-coil domain-containing protein (DUF2360) Allexi_40kDa PF05549.6 ETO35247.1 - 0.064 12.5 4.4 0.038 13.2 1.2 1.9 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF4070 PF13282.1 ETO35247.1 - 0.073 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4070) Lge1 PF11488.3 ETO35247.1 - 0.2 11.8 6.0 0.69 10.1 1.1 3.3 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 DUF241 PF03087.9 ETO35247.1 - 0.65 9.4 12.4 0.046 13.1 2.1 3.1 3 0 0 3 3 3 0 Arabidopsis protein of unknown function Flagellin_N PF00669.15 ETO35249.1 - 0.072 12.8 1.5 0.25 11.1 0.2 2.2 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region XPC-binding PF09280.6 ETO35249.1 - 0.55 9.7 4.5 9.9 5.7 0.1 3.4 3 0 0 3 3 3 0 XPC-binding domain DUF1479 PF07350.7 ETO35251.1 - 0.023 13.1 0.5 0.023 13.1 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) Virul_Fac PF10139.4 ETO35251.1 - 0.37 8.6 12.6 0.48 8.2 8.7 1.0 1 0 0 1 1 1 0 Putative bacterial virulence factor Inp1 PF12634.2 ETO35251.1 - 0.6 9.7 10.9 2.6 7.7 0.3 2.5 1 1 1 2 2 2 0 Inheritance of peroxisomes protein 1 PNP_UDP_1 PF01048.15 ETO35252.1 - 1.9e-27 95.7 0.0 2.5e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Kelch_1 PF01344.20 ETO35253.1 - 8.5e-12 44.4 0.7 1.7e-07 30.6 0.2 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO35253.1 - 1.3e-07 31.4 1.7 0.0007 19.6 0.3 4.3 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO35253.1 - 2e-05 24.2 0.0 0.00097 18.8 0.0 2.9 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO35253.1 - 0.00038 20.3 0.3 1.8 8.6 0.4 4.3 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 ETO35253.1 - 0.0016 18.5 0.2 0.04 14.0 0.0 3.2 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO35253.1 - 1.7 8.5 10.1 9.7 6.1 0.0 4.1 5 1 0 5 5 5 0 Kelch motif CUE PF02845.11 ETO35254.1 - 0.0024 17.2 0.0 0.0053 16.2 0.0 1.6 1 0 0 1 1 1 1 CUE domain DUF3231 PF11553.3 ETO35254.1 - 7.4 6.0 10.0 0.11 12.0 1.2 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3231) WD40 PF00400.27 ETO35255.1 - 1.3e-46 154.8 9.5 7.3e-11 41.5 0.0 5.5 5 1 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO35255.1 - 2.5e-07 29.2 7.0 0.057 11.5 0.0 4.7 3 1 1 5 5 5 4 Nucleoporin Nup120/160 Ctr PF04145.10 ETO35256.1 - 0.12 12.3 2.5 0.49 10.4 1.8 1.9 1 1 0 1 1 1 0 Ctr copper transporter family Band_7 PF01145.20 ETO35257.1 - 8.6e-07 29.0 4.4 8.6e-07 29.0 3.1 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family GatB_Yqey PF02637.13 ETO35257.1 - 0.0065 16.1 1.1 0.012 15.2 0.8 1.4 1 0 0 1 1 1 1 GatB domain ANAPC15 PF15243.1 ETO35257.1 - 0.0067 16.4 0.4 0.01 15.8 0.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 15 DUF1465 PF07323.7 ETO35257.1 - 0.045 13.3 1.0 0.066 12.7 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) DUF4637 PF15470.1 ETO35257.1 - 0.099 12.2 0.2 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) SSP160 PF06933.6 ETO35258.1 - 0.13 10.1 9.7 0.19 9.6 6.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF4551 PF15087.1 ETO35258.1 - 0.25 9.6 11.1 0.32 9.2 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Zip PF02535.17 ETO35258.1 - 1.1 8.1 3.8 7.9 5.3 1.8 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Macoilin PF09726.4 ETO35258.1 - 1.2 7.2 10.6 1.6 6.9 7.4 1.2 1 0 0 1 1 1 0 Transmembrane protein Apt1 PF10351.4 ETO35258.1 - 5 5.8 20.9 0.2 10.5 6.2 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain Annexin PF00191.15 ETO35259.1 - 5.4e-18 64.6 2.6 5.9e-11 42.0 0.0 3.0 3 0 0 3 3 3 2 Annexin Glyco_hydro_38C PF07748.8 ETO35260.1 - 2.1e-32 112.5 0.1 2.7e-32 112.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain H_lectin PF09458.5 ETO35260.1 - 0.0093 15.5 1.9 0.0093 15.5 1.3 2.7 3 0 0 3 3 3 1 H-type lectin domain zf-H2C2_2 PF13465.1 ETO35261.1 - 1.9e-07 31.0 19.1 0.00034 20.7 2.1 4.8 3 1 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 ETO35261.1 - 1e-06 28.7 20.3 0.01 16.1 0.9 4.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETO35261.1 - 0.00012 22.1 17.8 0.0095 16.2 0.2 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.2 ETO35261.1 - 0.0049 17.0 0.3 0.0049 17.0 0.2 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type LIM PF00412.17 ETO35261.1 - 0.11 12.5 5.6 5.1 7.2 0.6 3.2 2 0 0 2 2 2 0 LIM domain zf-Di19 PF05605.7 ETO35261.1 - 0.42 10.7 9.5 0.83 9.8 2.7 3.1 2 2 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 ETO35261.1 - 2.1 8.5 16.1 0.29 11.3 0.4 3.6 3 1 1 4 4 4 0 Zinc-finger double-stranded RNA-binding Ribonuc_red_lgC PF02867.10 ETO35262.1 - 2.6e-155 518.0 0.4 1.3e-78 264.9 0.0 3.4 2 1 1 3 3 3 3 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 ETO35262.1 - 2.7e-21 75.1 0.0 5.4e-21 74.1 0.0 1.5 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 ETO35262.1 - 3.4e-12 46.6 0.0 7.1e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 ATP cone domain VWA_2 PF13519.1 ETO35263.1 - 0.0017 18.5 0.0 0.0049 16.9 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain DNA_topoisoIV PF00521.15 ETO35265.1 - 1.1e-89 301.2 4.1 4.4e-82 276.2 0.0 3.5 2 2 2 4 4 4 2 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 ETO35265.1 - 3.2e-18 65.5 5.7 3.2e-18 65.5 4.0 2.2 2 0 0 2 2 2 1 DNA gyrase B Toprim PF01751.17 ETO35265.1 - 3.7e-15 55.7 1.9 2.8e-14 52.8 0.0 3.3 3 0 0 3 3 3 1 Toprim domain HATPase_c PF02518.21 ETO35265.1 - 2.4e-10 40.0 0.0 5.1e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Actin PF00022.14 ETO35266.1 - 2.3e-08 32.9 0.0 2.7e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Actin GTP_EFTU_D4 PF14578.1 ETO35266.1 - 0.0016 18.0 0.2 0.0043 16.6 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 4 DUF3102 PF11300.3 ETO35268.1 - 0.016 15.1 0.3 0.03 14.3 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3102) PUB PF09409.5 ETO35268.1 - 0.054 13.2 2.8 0.32 10.7 0.4 2.7 2 1 0 2 2 2 0 PUB domain Rsa3 PF14615.1 ETO35268.1 - 0.094 12.0 0.0 0.28 10.4 0.0 1.8 1 0 0 1 1 1 0 Ribosome-assembly protein 3 Kelch_2 PF07646.10 ETO35269.1 - 0.051 13.3 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 Kelch motif FUN14 PF04930.10 ETO35269.1 - 0.12 12.6 1.8 0.15 12.3 0.0 2.1 3 0 0 3 3 3 0 FUN14 family DUF4131 PF13567.1 ETO35269.1 - 0.26 10.6 1.3 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Kua-UEV1_localn PF10520.4 ETO35269.1 - 1.4 8.5 9.3 3.8 7.1 0.3 3.0 3 0 0 3 3 3 0 Kua-ubiquitin conjugating enzyme hybrid localisation domain DUF2457 PF10446.4 ETO35270.1 - 0.00091 18.0 23.7 0.0013 17.5 16.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) SprA-related PF12118.3 ETO35270.1 - 0.01 15.2 13.2 0.013 14.8 9.2 1.1 1 0 0 1 1 1 0 SprA-related family RNA_pol_3_Rpc31 PF11705.3 ETO35270.1 - 0.013 15.4 23.6 0.013 15.4 16.3 1.9 1 1 1 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Daxx PF03344.10 ETO35270.1 - 0.018 13.5 25.3 0.026 13.0 17.6 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 ETO35270.1 - 0.027 12.4 26.3 0.04 11.8 18.3 1.2 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 ETO35270.1 - 0.032 13.5 11.8 0.069 12.4 8.2 1.5 1 0 0 1 1 1 0 NOA36 protein DUF1510 PF07423.6 ETO35270.1 - 3.5 6.9 29.0 5.9 6.1 20.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 ETO35270.1 - 8 4.3 27.6 12 3.7 19.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF202 PF02656.10 ETO35271.1 - 0.0002 21.5 0.3 0.00046 20.3 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF202) LMBR1 PF04791.11 ETO35271.1 - 4.7 5.6 9.7 8.8 4.7 6.7 1.6 1 1 0 1 1 1 0 LMBR1-like membrane protein YolD PF08863.5 ETO35273.1 - 0.13 12.1 1.8 0.23 11.3 1.3 1.5 1 0 0 1 1 1 0 YolD-like protein WD40 PF00400.27 ETO35274.1 - 1.8e-08 33.9 11.2 9.2e-05 22.1 1.4 4.5 3 2 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO35274.1 - 0.0027 15.9 0.2 0.86 7.6 0.0 2.0 1 1 0 2 2 2 2 Nucleoporin Nup120/160 AAA_22 PF13401.1 ETO35275.1 - 0.0028 17.8 0.0 0.011 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 ETO35275.1 - 0.014 14.4 0.0 0.028 13.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 ETO35275.1 - 0.024 15.4 1.1 0.41 11.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain UPF0079 PF02367.12 ETO35275.1 - 0.026 14.1 0.1 0.22 11.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 ETO35275.1 - 0.051 12.4 0.4 0.11 11.4 0.3 1.6 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.1 ETO35275.1 - 0.063 13.5 0.0 0.063 13.5 0.0 3.0 3 1 0 3 3 3 0 AAA domain IL15 PF02372.10 ETO35275.1 - 0.073 12.8 4.6 0.064 13.0 0.8 2.1 2 0 0 2 2 2 0 Interleukin 15 AAA_29 PF13555.1 ETO35275.1 - 0.079 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 ETO35275.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.7 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 ETO35275.1 - 0.2 11.8 1.1 1 9.5 0.0 2.4 2 0 0 2 2 2 0 RNA helicase DNA_ligase_ZBD PF03119.11 ETO35276.1 - 0.019 14.6 0.9 0.6 9.8 0.0 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-Mss51 PF13824.1 ETO35276.1 - 0.053 13.3 0.4 0.12 12.2 0.1 1.8 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 A2L_zn_ribbon PF08792.5 ETO35276.1 - 0.24 10.9 1.8 0.4 10.2 0.1 2.3 3 0 0 3 3 3 0 A2L zinc ribbon domain Pombe_5TM PF09437.5 ETO35278.1 - 0.33 10.3 10.9 0.027 13.9 1.5 2.7 2 1 1 3 3 3 0 Pombe specific 5TM protein WD40 PF00400.27 ETO35279.1 - 0.062 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 WD domain, G-beta repeat zf-C2H2_7 PF15269.1 ETO35280.1 - 0.15 11.9 2.6 9.7 6.1 0.4 2.7 1 1 1 2 2 2 0 Zinc-finger DUF1842 PF08896.5 ETO35281.1 - 0.015 15.0 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1842) CS PF04969.11 ETO35282.1 - 0.07 13.6 0.1 0.07 13.6 0.1 2.4 3 0 0 3 3 3 0 CS domain WD40 PF00400.27 ETO35283.1 - 3.6e-16 58.3 10.5 1.5e-08 34.2 0.0 4.5 4 1 0 4 4 4 3 WD domain, G-beta repeat WD40 PF00400.27 ETO35285.1 - 1.4e-86 281.5 19.7 1.8e-12 46.6 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO35285.1 - 6.1e-08 31.2 6.9 0.048 11.7 0.1 5.0 2 1 1 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO35285.1 - 3.9e-07 29.1 11.7 0.0087 14.8 0.1 5.3 1 1 4 5 5 5 3 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO35285.1 - 7.3e-07 27.8 0.3 0.00082 17.7 0.1 2.7 2 1 1 3 3 3 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 ETO35285.1 - 0.00084 18.8 0.1 0.015 14.7 0.0 2.5 1 1 0 1 1 1 1 PQQ-like domain PD40 PF07676.7 ETO35285.1 - 0.0014 18.2 9.9 8.2 6.2 0.0 6.3 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat DUF727 PF05303.7 ETO35285.1 - 0.0017 18.1 0.4 0.92 9.3 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF727) DPPIV_N PF00930.16 ETO35285.1 - 0.0025 16.4 0.1 1.8 7.0 0.0 4.0 1 1 4 5 5 5 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nbas_N PF15492.1 ETO35285.1 - 0.017 14.2 0.6 10 5.1 0.0 3.3 1 1 3 4 4 4 0 Neuroblastoma-amplified sequence, N terminal BBS2_Mid PF14783.1 ETO35285.1 - 0.028 14.2 2.3 6.3 6.6 0.0 4.6 3 2 2 5 5 5 0 Ciliary BBSome complex subunit 2, middle region Resistin PF06954.6 ETO35285.1 - 0.092 13.0 0.1 5.2 7.4 0.0 3.1 2 1 1 3 3 3 0 Resistin Proteasome_A_N PF10584.4 ETO35285.1 - 0.27 10.6 4.7 55 3.2 0.0 4.4 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature PDEase_I PF00233.14 ETO35286.1 - 2.6e-32 112.4 0.0 2.4e-29 102.7 0.0 3.1 2 1 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase MIP-T3 PF10243.4 ETO35286.1 - 7.2e-05 21.4 0.1 7.3e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Methyltransf_32 PF13679.1 ETO35286.1 - 0.028 14.0 0.6 0.054 13.1 0.4 1.4 1 0 0 1 1 1 0 Methyltransferase domain Alpha_GJ PF03229.8 ETO35286.1 - 1.5 9.1 17.7 1.8 8.9 4.4 2.5 2 0 0 2 2 2 0 Alphavirus glycoprotein J Striatin PF08232.7 ETO35286.1 - 1.8 8.8 7.6 6.8 7.0 0.5 2.4 2 0 0 2 2 2 0 Striatin family Phyto_Pns9_10 PF05878.6 ETO35286.1 - 2.8 6.8 8.8 0.065 12.2 0.6 1.9 2 0 0 2 2 2 0 Phytoreovirus nonstructural protein Pns9/Pns10 Baculo_PEP_C PF04513.7 ETO35287.1 - 0.77 9.5 19.3 0.75 9.6 1.4 4.0 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 ETO35287.1 - 3.7 6.6 6.3 1.9 7.6 1.1 2.2 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DUF849 PF05853.7 ETO35288.1 - 0.12 11.1 2.1 0.16 10.7 1.5 1.1 1 0 0 1 1 1 0 Prokaryotic protein of unknown function (DUF849) Paramyxo_ncap PF00973.14 ETO35288.1 - 2.4 6.7 10.6 3.6 6.1 7.4 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein AIP3 PF03915.8 ETO35289.1 - 0.0012 17.9 1.2 0.0014 17.6 0.8 1.0 1 0 0 1 1 1 1 Actin interacting protein 3 Rota_NSP4 PF01452.11 ETO35289.1 - 0.057 12.7 2.7 0.082 12.2 1.9 1.3 1 0 0 1 1 1 0 Rotavirus non structural protein Vps54 PF07928.7 ETO35289.1 - 0.062 13.4 1.7 0.084 13.0 0.4 1.8 2 0 0 2 2 2 0 Vps54-like protein SlyX PF04102.7 ETO35289.1 - 0.09 13.1 0.8 0.16 12.3 0.6 1.4 1 0 0 1 1 1 0 SlyX PcfJ PF14284.1 ETO35289.1 - 0.13 11.7 3.4 0.25 10.8 2.4 1.4 1 1 0 1 1 1 0 PcfJ-like protein DUF2935 PF11155.3 ETO35289.1 - 0.19 11.8 3.8 0.35 10.9 0.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) MAP7 PF05672.6 ETO35289.1 - 0.45 9.8 3.7 0.54 9.6 2.6 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Mvb12 PF09452.5 ETO35289.1 - 0.48 10.6 3.2 12 6.1 1.0 2.7 1 1 2 3 3 3 0 ESCRT-I subunit Mvb12 LAGLIDADG_1 PF00961.14 ETO35289.1 - 0.52 10.8 4.0 0.8 10.2 2.8 1.3 1 0 0 1 1 1 0 LAGLIDADG endonuclease WD40 PF00400.27 ETO35290.1 - 1.9e-50 167.0 17.0 3.8e-11 42.4 0.2 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO35290.1 - 4.9e-07 28.2 6.5 0.16 10.0 0.2 5.2 1 1 1 5 5 5 3 Nucleoporin Nup120/160 zf-RING_2 PF13639.1 ETO35290.1 - 0.0022 17.7 1.1 0.0071 16.1 0.8 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO35290.1 - 0.0094 15.9 0.3 0.047 13.7 0.2 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) YjcZ PF13990.1 ETO35290.1 - 0.033 13.3 7.3 0.057 12.5 5.0 1.4 1 0 0 1 1 1 0 YjcZ-like protein HR1 PF02185.11 ETO35290.1 - 0.76 9.5 19.3 0.48 10.2 6.2 3.5 1 1 0 2 2 2 0 Hr1 repeat Baculo_PEP_C PF04513.7 ETO35290.1 - 1.1 9.0 18.0 0.088 12.6 5.1 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF848 PF05852.6 ETO35290.1 - 5.4 6.8 21.0 3.5 7.4 4.2 3.1 1 1 2 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) GTP-bdg_N PF13167.1 ETO35290.1 - 5.5 7.1 14.5 0.31 11.1 3.5 2.8 1 1 1 2 2 2 0 GTP-binding GTPase N-terminal DUF972 PF06156.8 ETO35290.1 - 7.5 6.9 23.9 0.34 11.2 5.9 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) eRF1_1 PF03463.10 ETO35291.1 - 1.3e-07 31.2 0.1 2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 PDDEXK_5 PF11645.3 ETO35291.1 - 0.044 13.4 0.1 0.57 9.8 0.1 2.1 1 1 0 1 1 1 0 PD-(D/E)XK endonuclease Snf7 PF03357.16 ETO35292.1 - 4.8e-21 74.8 29.6 1e-18 67.3 20.5 2.1 1 1 0 1 1 1 1 Snf7 YL1 PF05764.8 ETO35292.1 - 0.031 13.8 15.3 0.049 13.2 10.6 1.3 1 0 0 1 1 1 0 YL1 nuclear protein HisKA PF00512.20 ETO35292.1 - 0.078 12.9 1.7 0.14 12.1 0.2 2.1 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain PIG-S PF10510.4 ETO35292.1 - 0.88 8.1 7.6 2.8 6.4 1.1 2.0 1 1 1 2 2 2 0 Phosphatidylinositol-glycan biosynthesis class S protein RhoGAP PF00620.22 ETO35294.1 - 4.2e-07 29.7 1.8 3e-05 23.6 1.2 2.6 1 1 0 1 1 1 1 RhoGAP domain DUF1754 PF08555.5 ETO35294.1 - 0.0062 17.1 5.6 0.0062 17.1 3.9 3.5 4 0 0 4 4 4 1 Eukaryotic family of unknown function (DUF1754) Vfa1 PF08432.5 ETO35294.1 - 5.7 6.9 29.2 0.53 10.2 4.2 3.5 4 0 0 4 4 4 0 AAA-ATPase Vps4-associated protein 1 WD40 PF00400.27 ETO35296.1 - 8.2e-08 31.8 0.9 4.5e-07 29.5 0.0 2.4 3 0 0 3 3 3 1 WD domain, G-beta repeat Y_phosphatase PF00102.22 ETO35297.1 - 2.3e-10 40.1 0.1 3.4e-10 39.6 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 ETO35297.1 - 9.9e-08 31.6 0.0 1.8e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.7 ETO35297.1 - 0.00064 19.2 0.1 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase2 PF03162.8 ETO35297.1 - 0.001 18.4 0.1 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 ETO35297.1 - 0.0057 16.9 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 ETO35297.1 - 0.0087 16.1 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate UQ_con PF00179.21 ETO35298.1 - 8.1e-34 116.0 1.2 4.3e-33 113.6 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Pox_Ag35 PF03286.9 ETO35298.1 - 0.011 15.2 1.9 0.016 14.7 1.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF3108 PF11306.3 ETO35298.1 - 0.014 15.0 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3108) Prok-E2_B PF14461.1 ETO35298.1 - 0.017 14.8 0.0 0.027 14.2 0.0 1.5 1 1 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.17 ETO35298.1 - 0.018 14.9 0.1 0.026 14.4 0.1 1.3 1 1 0 1 1 1 0 RWD domain Hom_end_hint PF05203.11 ETO35298.1 - 0.038 13.7 0.3 0.037 13.7 0.2 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint Folate_carrier PF01770.13 ETO35298.1 - 0.1 11.0 1.0 0.13 10.7 0.7 1.1 1 0 0 1 1 1 0 Reduced folate carrier Kei1 PF08552.6 ETO35298.1 - 0.13 11.8 1.1 0.18 11.4 0.7 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 OSTbeta PF15048.1 ETO35298.1 - 0.14 12.2 2.8 0.21 11.6 2.0 1.3 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DEP PF00610.16 ETO35299.1 - 1.2e-06 28.2 0.4 4.2e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Claudin_3 PF06653.6 ETO35299.1 - 2.6 7.7 4.8 4.4 7.0 3.0 1.6 2 0 0 2 2 2 0 Tight junction protein, Claudin-like Pex14_N PF04695.8 ETO35299.1 - 7.5 6.6 9.3 25 4.9 4.9 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SLA_LP_auto_ag PF05889.8 ETO35300.1 - 1.6e-13 49.9 0.0 3.6e-13 48.7 0.0 1.5 2 0 0 2 2 2 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Rad21_Rec8_N PF04825.8 ETO35300.1 - 0.0042 17.0 0.2 0.0097 15.8 0.1 1.6 2 0 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein WBP-1 PF11669.3 ETO35301.1 - 0.17 11.9 7.5 0.81 9.8 5.1 2.1 1 1 1 2 2 2 0 WW domain-binding protein 1 ART PF01129.13 ETO35303.1 - 0.00024 20.3 0.9 0.00024 20.3 0.6 2.0 2 0 0 2 2 2 1 NAD:arginine ADP-ribosyltransferase PUB PF09409.5 ETO35304.1 - 0.00031 20.4 0.7 0.00031 20.4 0.5 3.0 3 1 0 3 3 3 1 PUB domain DUF2175 PF09943.4 ETO35305.1 - 0.081 12.9 1.3 0.72 9.9 0.0 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) DUF3768 PF12599.3 ETO35306.1 - 0.068 13.0 0.2 6.4 6.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3768) PUB PF09409.5 ETO35307.1 - 0.02 14.6 0.9 0.057 13.1 0.7 1.9 1 1 0 1 1 1 0 PUB domain Gly_radical PF01228.16 ETO35308.1 - 0.03 14.6 0.1 0.031 14.6 0.1 1.1 1 0 0 1 1 1 0 Glycine radical DUF4524 PF15025.1 ETO35309.1 - 1.6e-08 34.1 0.0 3.6e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4524) POLO_box PF00659.13 ETO35309.1 - 0.016 15.1 1.2 6.8 6.7 0.1 2.7 2 0 0 2 2 2 0 POLO box duplicated region Tubulin PF00091.20 ETO35310.1 - 1.6e-28 100.0 0.0 2.7e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain CAT_RBD PF03123.10 ETO35311.1 - 0.033 13.8 0.1 0.099 12.3 0.1 1.8 1 0 0 1 1 1 0 CAT RNA binding domain DUF2552 PF10827.3 ETO35312.1 - 0.051 13.5 0.0 2.6 8.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2552) Tim54 PF11711.3 ETO35314.1 - 0.011 14.3 7.6 0.013 14.0 5.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Daxx PF03344.10 ETO35314.1 - 1.7 7.0 29.1 1.9 6.8 20.2 1.0 1 0 0 1 1 1 0 Daxx Family Osteopontin PF00865.13 ETO35314.1 - 1.9 7.6 28.8 2.3 7.3 19.9 1.2 1 0 0 1 1 1 0 Osteopontin CDC45 PF02724.9 ETO35314.1 - 8.2 4.3 25.1 9.2 4.1 17.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 ETO35314.1 - 8.6 4.1 33.9 9.6 3.9 23.5 1.0 1 0 0 1 1 1 0 Nop14-like family zf-SAP30 PF13866.1 ETO35316.1 - 0.29 10.8 1.4 0.55 9.9 0.9 1.5 1 1 0 1 1 1 0 SAP30 zinc-finger WD40 PF00400.27 ETO35317.1 - 1.1e-39 132.8 16.7 1.3e-09 37.5 0.0 5.2 4 1 1 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO35317.1 - 8e-05 20.9 0.1 1.1 7.2 0.0 3.1 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Couple_hipA PF13657.1 ETO35319.1 - 2.5e-08 34.1 0.0 7.9e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 HipA N-terminal domain HTH_19 PF12844.2 ETO35319.1 - 8.8e-08 32.0 0.7 2.3e-06 27.5 0.0 3.3 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_3 PF01381.17 ETO35319.1 - 2.6e-06 27.1 0.0 7.7e-06 25.6 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 ETO35319.1 - 0.00011 22.2 0.0 0.00021 21.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.1 ETO35319.1 - 0.00035 20.3 0.1 0.0016 18.2 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain DUF3970 PF13113.1 ETO35319.1 - 0.0083 15.7 1.2 0.0083 15.7 0.8 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3970) HTH_25 PF13413.1 ETO35319.1 - 0.053 13.1 0.0 0.22 11.1 0.0 2.0 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_40 PF14493.1 ETO35319.1 - 1.3 9.3 7.4 0.37 11.0 0.4 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain 2OG-FeII_Oxy_3 PF13640.1 ETO35320.1 - 0.013 15.9 0.0 0.024 15.1 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily TPR_12 PF13424.1 ETO35322.1 - 2.7e-21 75.3 3.5 6.7e-15 54.7 0.2 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO35322.1 - 1.1e-08 34.6 1.0 0.00029 20.4 0.1 2.1 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETO35322.1 - 1.9e-08 33.5 9.6 0.00041 19.8 0.2 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO35322.1 - 8e-07 28.5 3.5 0.016 15.0 0.5 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO35322.1 - 9.3e-07 28.1 8.1 0.0034 17.0 0.6 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO35322.1 - 1.9e-06 27.6 0.0 0.00035 20.4 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO35322.1 - 2e-06 27.1 0.2 0.016 14.9 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO35322.1 - 3.8e-05 23.7 0.7 5.4e-05 23.2 0.5 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 Pep3_Vps18 PF05131.9 ETO35322.1 - 0.012 15.0 0.7 1.5 8.2 0.1 2.1 1 1 1 2 2 2 0 Pep3/Vps18/deep orange family 14-3-3 PF00244.15 ETO35322.1 - 0.013 14.5 0.2 0.015 14.4 0.1 1.1 1 0 0 1 1 1 0 14-3-3 protein TPR_3 PF07720.7 ETO35322.1 - 0.022 14.5 6.2 0.45 10.3 1.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETO35322.1 - 0.025 15.2 0.0 0.062 13.9 0.0 1.6 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.1 ETO35322.1 - 0.031 14.4 4.6 0.17 12.1 1.9 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETO35322.1 - 0.071 13.7 0.0 12 6.8 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2600 PF10776.4 ETO35322.1 - 0.088 11.6 0.5 0.095 11.5 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2600) Fis1_TPR_C PF14853.1 ETO35322.1 - 0.09 12.6 1.4 2.2 8.2 0.1 2.2 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat HNH PF01844.18 ETO35322.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 HNH endonuclease TPR_19 PF14559.1 ETO35322.1 - 0.12 12.7 0.3 0.4 11.0 0.2 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat Laminin_G_3 PF13385.1 ETO35324.1 - 4.6e-13 49.7 0.0 8.2e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.19 ETO35324.1 - 0.003 17.5 0.1 0.0094 15.9 0.0 1.8 1 0 0 1 1 1 1 Laminin G domain RNB PF00773.14 ETO35326.1 - 1.2e-17 64.2 0.0 2.6e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 RNB domain DUF4246 PF14033.1 ETO35327.1 - 1.7e-10 40.1 1.4 0.00013 20.7 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF4246) Translin PF01997.11 ETO35328.1 - 0.0013 18.4 0.3 0.0017 18.0 0.2 1.2 1 0 0 1 1 1 1 Translin family CCDC155 PF14662.1 ETO35328.1 - 0.031 13.8 1.6 0.64 9.5 0.1 2.0 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 DUF4164 PF13747.1 ETO35328.1 - 0.068 13.3 0.6 1 9.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) WEMBL PF05701.6 ETO35328.1 - 0.34 9.3 3.4 0.83 8.0 2.4 1.5 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Spc24 PF08286.6 ETO35328.1 - 0.9 9.2 3.3 7 6.3 0.3 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Beta_helix PF13229.1 ETO35330.1 - 2.6e-06 27.2 5.3 7.5e-05 22.5 0.6 2.3 2 0 0 2 2 2 2 Right handed beta helix region PPR_2 PF13041.1 ETO35331.1 - 1.9e-15 56.5 4.6 6.6e-11 42.0 0.3 3.4 2 1 1 3 3 3 3 PPR repeat family PPR PF01535.15 ETO35331.1 - 3.9e-12 45.2 1.1 6.1e-06 25.8 0.0 3.3 3 0 0 3 3 3 2 PPR repeat PPR_1 PF12854.2 ETO35331.1 - 9e-12 44.2 1.2 6.8e-06 25.4 0.0 3.2 3 0 0 3 3 3 3 PPR repeat PPR_3 PF13812.1 ETO35331.1 - 1.7e-10 40.3 0.0 3.5e-05 23.7 0.0 2.9 2 0 0 2 2 2 2 Pentatricopeptide repeat domain ATP13 PF12921.2 ETO35331.1 - 0.053 12.8 0.6 0.61 9.4 0.1 2.4 1 1 1 2 2 2 0 Mitochondrial ATPase expression DUF3606 PF12244.3 ETO35331.1 - 0.094 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) SPX PF03105.14 ETO35332.1 - 0.045 13.5 14.4 0.091 12.5 7.0 2.2 2 0 0 2 2 2 0 SPX domain DUF506 PF04720.7 ETO35332.1 - 4 7.0 11.5 1.5 8.3 5.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF506) Secretin_N_2 PF07655.8 ETO35332.1 - 5.2 7.5 19.0 20 5.6 8.6 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain Apis_Csd PF11671.3 ETO35332.1 - 6 6.6 28.2 1.9 8.2 4.1 2.6 2 0 0 2 2 2 0 Complementary sex determiner protein DHC_N1 PF08385.7 ETO35333.1 - 7.7e-19 67.4 3.1 7.7e-19 67.4 2.2 2.1 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 DUF4338 PF14236.1 ETO35333.1 - 0.43 9.1 8.4 4.6 5.8 4.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4338) TSA PF03249.8 ETO35333.1 - 0.44 9.0 15.0 0.066 11.7 7.4 1.6 2 0 0 2 2 2 0 Type specific antigen BAF1_ABF1 PF04684.8 ETO35333.1 - 1.1 8.0 11.1 1.7 7.3 7.7 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Vps39_2 PF10367.4 ETO35333.1 - 5.1 7.3 10.7 7.9 6.7 3.9 2.9 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 DHC_N1 PF08385.7 ETO35334.1 - 1.4e-58 198.6 5.7 1.4e-58 198.6 3.9 3.1 3 1 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 ETO35334.1 - 1.3e-10 40.3 2.2 1.3e-10 40.3 1.5 4.3 4 2 1 6 6 6 1 Dynein heavy chain, N-terminal region 2 DHC_N2 PF08393.8 ETO35335.1 - 1e-88 297.6 7.0 2.3e-88 296.4 4.9 1.7 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 ETO35335.1 - 4.8e-63 212.7 0.1 2.6e-55 187.4 0.0 3.0 2 1 1 3 3 3 2 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 ETO35335.1 - 1.8e-30 105.5 0.0 2.5e-12 46.7 0.0 5.7 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_8 PF12780.2 ETO35335.1 - 1.1e-29 103.2 0.1 2.9e-29 101.8 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 ETO35335.1 - 1.4e-25 89.9 0.0 1.4e-23 83.3 0.0 3.0 3 0 0 3 3 3 1 P-loop containing dynein motor region D3 AAA PF00004.24 ETO35335.1 - 2.4e-15 56.9 0.0 0.0088 16.2 0.0 5.8 5 1 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETO35335.1 - 5.9e-15 55.5 0.0 0.0012 18.9 0.0 5.8 4 1 1 5 5 4 4 AAA domain AAA_33 PF13671.1 ETO35335.1 - 2.9e-11 43.4 0.0 0.022 14.6 0.0 5.2 4 0 0 4 4 4 3 AAA domain AAA_16 PF13191.1 ETO35335.1 - 5.7e-11 42.7 0.0 0.52 10.2 0.0 5.1 4 1 0 4 4 4 3 AAA ATPase domain AAA_17 PF13207.1 ETO35335.1 - 4e-08 34.0 1.5 6.8 7.5 0.0 5.8 6 0 0 6 6 4 0 AAA domain IstB_IS21 PF01695.12 ETO35335.1 - 1.1e-07 31.4 0.7 0.046 13.1 0.0 4.5 4 0 0 4 4 4 2 IstB-like ATP binding protein AAA_19 PF13245.1 ETO35335.1 - 8.9e-07 28.5 0.3 0.28 10.9 0.0 4.5 5 0 0 5 5 4 2 Part of AAA domain ABC_tran PF00005.22 ETO35335.1 - 1.3e-06 28.7 0.8 1.1 9.5 0.0 4.8 5 0 0 5 5 4 2 ABC transporter AAA_29 PF13555.1 ETO35335.1 - 1.5e-06 27.5 0.0 1.6 8.2 0.0 4.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.1 ETO35335.1 - 3.1e-06 27.2 0.1 4.7 7.2 0.0 5.9 5 1 0 6 6 6 0 Sigma-54 interaction domain RNA_helicase PF00910.17 ETO35335.1 - 4.8e-06 26.7 0.0 2.5 8.3 0.0 4.7 4 0 0 4 4 4 1 RNA helicase Zeta_toxin PF06414.7 ETO35335.1 - 1.4e-05 24.2 0.2 0.04 13.0 0.0 4.1 4 0 0 4 4 3 1 Zeta toxin FtsK_SpoIIIE PF01580.13 ETO35335.1 - 1.5e-05 24.5 0.0 0.42 10.0 0.0 3.9 3 0 0 3 3 3 2 FtsK/SpoIIIE family T2SE PF00437.15 ETO35335.1 - 1.6e-05 23.9 0.1 0.044 12.6 0.0 3.8 4 0 0 4 4 4 1 Type II/IV secretion system protein AAA_18 PF13238.1 ETO35335.1 - 3.3e-05 24.2 0.1 6.8 7.0 0.0 5.6 5 0 0 5 5 4 0 AAA domain DUF258 PF03193.11 ETO35335.1 - 4.1e-05 22.8 0.0 1.9 7.6 0.0 3.6 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_30 PF13604.1 ETO35335.1 - 4.4e-05 23.1 0.2 5.8 6.4 0.0 4.3 4 0 0 4 4 4 0 AAA domain Mg_chelatase PF01078.16 ETO35335.1 - 0.00011 21.4 0.4 0.71 8.9 0.0 4.7 5 0 0 5 5 5 1 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 ETO35335.1 - 0.00017 21.1 0.3 5.6 6.3 0.0 4.7 5 0 0 5 5 5 0 AAA-like domain AAA_14 PF13173.1 ETO35335.1 - 0.00019 21.3 0.0 0.32 10.9 0.0 4.2 4 0 0 4 4 4 1 AAA domain Sigma54_activat PF00158.21 ETO35335.1 - 0.00021 20.8 0.0 7.9 5.9 0.0 3.6 3 0 0 3 3 3 0 Sigma-54 interaction domain Guanylate_kin PF00625.16 ETO35335.1 - 0.00025 20.5 0.1 0.026 13.9 0.0 3.2 3 0 0 3 3 3 1 Guanylate kinase AAA_28 PF13521.1 ETO35335.1 - 0.00064 19.7 0.0 27 4.6 0.0 5.3 4 0 0 4 4 4 0 AAA domain AAA_23 PF13476.1 ETO35335.1 - 0.001 19.4 1.5 13 6.0 0.0 5.0 4 1 0 4 4 3 0 AAA domain AAA_25 PF13481.1 ETO35335.1 - 0.0017 17.8 4.5 0.15 11.4 0.0 4.4 4 1 0 4 4 3 1 AAA domain Gtr1_RagA PF04670.7 ETO35335.1 - 0.0044 16.1 0.1 4.9 6.2 0.1 4.1 4 0 0 4 4 4 0 Gtr1/RagA G protein conserved region NACHT PF05729.7 ETO35335.1 - 0.019 14.6 0.3 7.3 6.2 0.0 4.5 4 0 0 4 4 4 0 NACHT domain RuvB_N PF05496.7 ETO35335.1 - 0.019 14.0 0.0 21 4.0 0.0 3.4 3 0 0 3 3 3 0 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 ETO35335.1 - 0.054 13.0 0.2 10 5.5 0.0 4.0 4 0 0 4 4 4 0 AAA domain AAA_11 PF13086.1 ETO35335.1 - 0.15 11.6 0.5 5 6.6 0.0 3.5 4 0 0 4 4 4 0 AAA domain Serpin PF00079.15 ETO35337.1 - 2.2e-22 79.7 0.2 3.9e-22 78.8 0.1 1.3 1 1 0 1 1 1 1 Serpin (serine protease inhibitor) DUF4337 PF14235.1 ETO35337.1 - 0.5 10.1 2.4 0.92 9.3 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) TPR_11 PF13414.1 ETO35338.1 - 0.0044 16.6 0.1 0.045 13.4 0.0 2.0 1 1 1 2 2 2 2 TPR repeat WD40 PF00400.27 ETO35339.1 - 1.5e-38 129.3 24.1 1.8e-10 40.2 0.0 6.3 5 1 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO35339.1 - 5.2e-05 21.5 3.2 0.0013 16.9 0.2 2.6 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF2678 PF10856.3 ETO35340.1 - 9.4 6.0 6.8 5.5 6.7 3.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2678) Neur_chan_memb PF02932.11 ETO35341.1 - 0.0075 16.1 2.8 0.012 15.5 0.0 2.1 1 1 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region DUF1201 PF06716.6 ETO35341.1 - 0.016 15.0 5.6 0.035 13.9 3.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1201) 7tm_1 PF00001.16 ETO35341.1 - 0.022 13.9 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF1049 PF06305.6 ETO35341.1 - 1.3 8.5 4.1 0.66 9.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) PBP1_TM PF14812.1 ETO35342.1 - 0.7 10.2 3.5 1.3 9.3 2.4 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal adh_short PF00106.20 ETO35344.1 - 8.2e-22 77.8 0.0 3e-14 53.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 ETO35344.1 - 6.6e-11 42.4 0.1 6.4e-06 26.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 ETO35344.1 - 1.6e-07 31.5 0.0 0.00025 21.1 0.0 2.1 2 0 0 2 2 2 2 NADH(P)-binding KR PF08659.5 ETO35344.1 - 5.8e-06 26.0 0.0 1.6e-05 24.6 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 ETO35344.1 - 0.015 14.7 0.0 0.043 13.2 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 7TM_GPCR_Srt PF10321.4 ETO35344.1 - 0.015 14.0 0.1 0.027 13.2 0.1 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt NmrA PF05368.8 ETO35344.1 - 0.037 13.2 0.0 0.12 11.6 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family RRP14 PF15459.1 ETO35345.1 - 0.88 9.6 5.4 1.8 8.7 3.7 1.5 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 CDC45 PF02724.9 ETO35345.1 - 2.6 5.9 7.7 3.2 5.6 5.3 1.0 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.27 ETO35346.1 - 3.7e-24 83.6 14.6 1.3e-11 43.8 0.0 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO35346.1 - 0.0006 18.0 0.6 1.9 6.4 0.1 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 TetM_leader PF08076.6 ETO35346.1 - 0.14 11.7 4.3 5.5 6.6 0.0 2.6 2 0 0 2 2 2 0 Tetracycline resistance determinant leader peptide WD40 PF00400.27 ETO35347.1 - 5.3e-76 248.0 15.3 1.8e-11 43.4 0.3 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO35347.1 - 8.8e-08 30.7 12.6 0.2 9.7 0.1 5.5 1 1 4 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO35347.1 - 1.2e-06 27.5 5.9 0.35 9.5 0.2 4.4 1 1 3 4 4 4 3 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO35347.1 - 0.00013 20.4 2.6 0.28 9.4 0.1 3.2 1 1 3 4 4 4 2 Cytochrome D1 heme domain Str_synth PF03088.11 ETO35347.1 - 0.00026 20.9 0.4 4 7.5 0.0 4.7 3 1 2 5 5 5 1 Strictosidine synthase DUF1258 PF06869.7 ETO35347.1 - 0.00066 18.8 1.1 6.4 5.7 0.1 3.6 1 1 2 4 4 4 2 Protein of unknown function (DUF1258) Coatomer_WDAD PF04053.9 ETO35347.1 - 0.014 14.2 3.7 0.48 9.1 0.0 3.0 1 1 1 3 3 3 0 Coatomer WD associated region Proteasome_A_N PF10584.4 ETO35347.1 - 0.015 14.6 3.5 1.9 7.8 0.0 4.0 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature DUF4221 PF13970.1 ETO35347.1 - 0.015 14.6 0.2 1.5 8.0 0.0 2.8 1 1 1 3 3 3 0 Domain of unknown function (DUF4221) PLD_C PF12357.3 ETO35347.1 - 0.023 14.2 0.0 17 5.0 0.0 3.6 2 1 1 3 3 3 0 Phospholipase D C terminal DUF3732 PF12532.3 ETO35347.1 - 0.073 12.5 0.2 31 3.9 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3732) Resistin PF06954.6 ETO35347.1 - 0.086 13.1 2.9 60 4.0 0.0 4.5 3 2 3 6 6 6 0 Resistin PD40 PF07676.7 ETO35347.1 - 0.1 12.2 6.6 21 4.9 0.1 4.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat GST_N_3 PF13417.1 ETO35349.1 - 0.0003 20.9 0.0 0.23 11.7 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETO35349.1 - 0.0056 16.6 0.1 0.062 13.3 0.1 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain AlgF PF11182.3 ETO35350.1 - 0.01 15.4 0.3 0.016 14.9 0.2 1.2 1 0 0 1 1 1 0 Alginate O-acetyl transferase AlgF AAA_16 PF13191.1 ETO35351.1 - 3.3e-05 23.9 0.0 4.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 ETO35351.1 - 0.00036 20.6 0.0 0.00073 19.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 ETO35351.1 - 0.0029 16.5 0.0 0.0034 16.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NACHT PF05729.7 ETO35351.1 - 0.0096 15.5 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain FtsK_SpoIIIE PF01580.13 ETO35351.1 - 0.01 15.3 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family Sigma54_activat PF00158.21 ETO35351.1 - 0.025 14.0 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.1 ETO35351.1 - 0.027 13.9 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 ETO35351.1 - 0.054 13.6 0.0 0.076 13.2 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DAP3 PF10236.4 ETO35351.1 - 0.095 11.6 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Arch_ATPase PF01637.13 ETO35351.1 - 0.12 12.0 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase NTPase_1 PF03266.10 ETO35351.1 - 0.15 11.7 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 NTPase TIP49 PF06068.8 ETO35351.1 - 0.15 10.7 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus SH2 PF00017.19 ETO35352.1 - 6.3e-08 32.3 0.0 1.7e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 SH2 domain NACHT PF05729.7 ETO35352.1 - 0.026 14.1 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF4264 PF14084.1 ETO35352.1 - 0.059 12.7 0.3 0.12 11.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) Peptidase_S49_N PF08496.5 ETO35353.1 - 0.074 12.8 1.9 0.071 12.8 1.3 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TMEMspv1-c74-12 PF11044.3 ETO35353.1 - 0.24 10.9 7.8 0.32 10.5 5.4 1.2 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein NST1 PF13945.1 ETO35353.1 - 1.5 8.8 7.3 1.6 8.7 5.1 1.0 1 0 0 1 1 1 0 Salt tolerance down-regulator Med19 PF10278.4 ETO35353.1 - 7.1 6.2 9.3 7.6 6.1 6.5 1.0 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 BLVR PF06375.6 ETO35353.1 - 8.7 6.1 10.0 9.5 6.0 6.9 1.0 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) COPIIcoated_ERV PF07970.7 ETO35354.1 - 3.2e-56 190.4 1.7 3.6e-56 190.2 1.2 1.0 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter DUF1517 PF07466.6 ETO35355.1 - 0.15 11.0 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) ATP-synt_8 PF00895.15 ETO35355.1 - 1.4 9.1 0.0 1.4 9.1 0.0 2.7 2 1 1 3 3 3 0 ATP synthase protein 8 TRAP_alpha PF03896.11 ETO35356.1 - 0.1 11.6 3.1 0.14 11.1 2.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.9 ETO35356.1 - 0.4 8.6 7.1 0.44 8.5 4.9 1.2 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.1 ETO35356.1 - 1.1 8.9 4.5 2.5 7.7 3.1 1.6 1 0 0 1 1 1 0 FAM176 family Vfa1 PF08432.5 ETO35356.1 - 1.8 8.5 14.5 0.38 10.7 7.2 1.9 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Conotoxin PF02950.12 ETO35356.1 - 2.8 8.8 6.9 49 4.8 0.0 2.7 2 0 0 2 2 2 0 Conotoxin Sporozoite_P67 PF05642.6 ETO35356.1 - 6 4.5 9.5 8.5 4.0 6.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4637 PF15470.1 ETO35356.1 - 9.2 5.8 8.2 1.4 8.5 2.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) Tubulin PF00091.20 ETO35357.1 - 7.8e-50 169.6 0.0 4.2e-36 124.8 0.0 2.0 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Lipase_3 PF01764.20 ETO35357.1 - 0.00091 18.8 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Tubulin_C PF03953.12 ETO35358.1 - 8.9e-27 93.6 0.0 1.4e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Peptidase_S10 PF00450.17 ETO35359.1 - 2.9e-19 69.5 0.1 3e-19 69.4 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Trs65 PF12735.2 ETO35359.1 - 0.048 12.9 0.1 0.061 12.6 0.1 1.1 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 Tubulin PF00091.20 ETO35360.1 - 5.9e-43 147.1 0.0 8.8e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO35360.1 - 5.2e-30 104.0 0.0 8.5e-30 103.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Gly_kinase PF02595.10 ETO35360.1 - 0.14 10.8 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Glycerate kinase family WD40 PF00400.27 ETO35364.1 - 2.3e-42 141.3 3.9 2.3e-13 49.4 0.0 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO35364.1 - 1e-05 23.9 0.2 0.031 12.4 0.0 2.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO35364.1 - 0.041 12.6 0.7 0.8 8.3 0.0 2.6 1 1 0 3 3 3 0 Nup133 N terminal like GSIII_N PF12437.3 ETO35365.1 - 0.1 12.0 1.1 0.12 11.8 0.7 1.1 1 0 0 1 1 1 0 Glutamine synthetase type III N terminal DUF999 PF06198.6 ETO35365.1 - 0.4 10.4 5.0 0.47 10.2 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF999) WD40 PF00400.27 ETO35366.1 - 6e-18 63.9 19.3 4.1e-08 32.8 0.2 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 ETO35366.1 - 1.5e-05 24.7 0.4 0.57 9.8 0.0 3.4 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Spo12 PF05032.7 ETO35366.1 - 0.0047 16.5 1.2 0.018 14.6 0.8 2.1 1 0 0 1 1 1 1 Spo12 family WD40 PF00400.27 ETO35368.1 - 6.4e-24 82.9 3.4 2e-12 46.4 0.3 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO35368.1 - 0.022 14.9 3.5 4.6 7.5 0.0 3.3 2 1 2 4 4 4 0 Kelch motif vATP-synt_E PF01991.13 ETO35368.1 - 0.028 13.6 3.7 0.039 13.2 2.6 1.1 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit PQQ_2 PF13360.1 ETO35368.1 - 0.033 13.6 0.1 0.65 9.4 0.0 2.0 1 1 1 2 2 2 0 PQQ-like domain Toxin_64 PF15542.1 ETO35368.1 - 0.058 13.9 0.4 0.13 12.8 0.3 1.6 1 0 0 1 1 1 0 Putative toxin 64 PQQ_3 PF13570.1 ETO35368.1 - 0.078 13.2 0.1 4.2 7.7 0.1 2.5 2 1 0 2 2 2 0 PQQ-like domain Nup160 PF11715.3 ETO35368.1 - 0.18 9.9 1.6 0.99 7.4 0.0 2.3 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Sigma_reg_C PF13791.1 ETO35368.1 - 0.48 10.4 3.5 0.34 10.9 1.3 1.6 2 0 0 2 2 2 0 Sigma factor regulator C-terminal Proteasome PF00227.21 ETO35369.1 - 8.2e-05 21.9 0.2 0.00018 20.8 0.2 1.6 1 0 0 1 1 1 1 Proteasome subunit RRM_1 PF00076.17 ETO35370.1 - 2.7e-15 55.7 0.4 2.3e-14 52.7 0.1 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO35370.1 - 1.3e-10 41.0 0.0 3.6e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO35370.1 - 0.00063 19.5 0.0 0.0016 18.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_18 PF13238.1 ETO35370.1 - 0.46 10.8 3.7 0.3 11.4 0.3 2.3 3 0 0 3 3 3 0 AAA domain Sgf11 PF08209.6 ETO35371.1 - 0.059 12.6 0.3 0.12 11.7 0.2 1.5 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) UPF0547 PF10571.4 ETO35371.1 - 3 7.6 5.2 4.3 7.1 0.1 3.2 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 WD40 PF00400.27 ETO35372.1 - 9.5e-11 41.1 2.5 3.9e-10 39.2 1.0 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO35372.1 - 0.0011 17.1 0.3 0.0015 16.7 0.2 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 WD40 PF00400.27 ETO35373.1 - 1.1e-40 136.0 9.4 1.3e-12 47.0 0.2 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO35373.1 - 7.9e-11 40.7 1.8 0.0024 16.0 0.0 3.9 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO35373.1 - 0.0014 17.4 9.3 0.32 9.6 3.5 3.0 1 1 2 3 3 3 3 Nup133 N terminal like RED_C PF07807.6 ETO35373.1 - 0.016 15.3 0.1 7.8 6.7 0.0 3.2 2 1 1 3 3 3 0 RED-like protein C-terminal region CENP-T PF15511.1 ETO35374.1 - 1.7 7.7 12.4 3.1 6.9 8.6 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF2457 PF10446.4 ETO35374.1 - 6.8 5.3 37.6 0.093 11.4 21.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) TyeA PF09059.5 ETO35375.1 - 0.12 12.3 1.0 17 5.4 0.0 2.4 1 1 1 2 2 2 0 TyeA WD40 PF00400.27 ETO35376.1 - 1e-05 25.2 0.3 2.2e-05 24.1 0.2 1.7 2 0 0 2 2 2 1 WD domain, G-beta repeat WD40 PF00400.27 ETO35377.1 - 2.3e-14 52.6 5.5 4.9e-11 42.0 0.6 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat TetM_leader PF08076.6 ETO35377.1 - 0.68 9.5 3.3 3.2 7.3 0.3 2.6 2 0 0 2 2 2 0 Tetracycline resistance determinant leader peptide zf-TRAF PF02176.13 ETO35378.1 - 5e-05 23.5 4.5 5e-05 23.5 3.1 2.7 3 0 0 3 3 3 1 TRAF-type zinc finger Cep57_CLD_2 PF14197.1 ETO35378.1 - 0.02 14.8 1.1 0.02 14.8 0.8 3.1 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 OTCace PF00185.19 ETO35378.1 - 0.11 12.3 2.7 1.9 8.3 0.0 2.5 2 0 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain GCD14 PF08704.5 ETO35378.1 - 0.82 9.1 9.3 1.5 8.2 6.5 1.5 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Atg14 PF10186.4 ETO35378.1 - 1.2 8.0 28.5 0.62 8.9 4.5 2.5 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_DNA_bd PF12329.3 ETO35378.1 - 1.3 8.8 35.6 0.21 11.4 15.8 3.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding DivIVA PF05103.8 ETO35378.1 - 2.1 8.4 34.2 0.21 11.6 10.7 3.3 2 1 1 3 3 3 0 DivIVA protein WD40 PF00400.27 ETO35379.1 - 5.4e-13 48.2 0.8 4.8e-12 45.2 0.1 2.4 2 1 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO35379.1 - 0.035 12.2 0.1 0.045 11.8 0.1 1.3 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Borrelia_P83 PF05262.6 ETO35379.1 - 0.075 11.2 0.0 0.087 11.0 0.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein TPR_12 PF13424.1 ETO35380.1 - 1.4e-34 117.8 7.0 3e-19 68.7 0.6 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO35380.1 - 8.5e-24 82.9 16.7 4.3e-11 42.2 0.2 3.5 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETO35380.1 - 2.5e-19 67.9 18.0 1.3e-06 27.7 0.4 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO35380.1 - 6.4e-18 63.0 5.4 7.7e-06 25.3 0.1 4.7 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO35380.1 - 6.7e-17 59.9 12.8 1.3e-06 27.8 0.2 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO35380.1 - 1.4e-15 56.6 0.8 0.00049 19.9 0.0 4.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO35380.1 - 1.2e-14 52.8 16.1 0.00058 19.4 1.2 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO35380.1 - 6.5e-10 38.4 4.0 0.031 14.4 0.1 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO35380.1 - 8.6e-08 32.1 0.0 0.19 12.4 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO35380.1 - 2.6e-06 27.9 0.2 0.11 13.1 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO35380.1 - 0.00018 21.5 11.4 0.065 13.3 0.7 3.6 1 1 3 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 ETO35380.1 - 0.00027 20.7 9.1 0.63 9.9 0.1 4.5 4 0 0 4 4 4 2 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 ETO35380.1 - 0.0063 16.9 4.1 8 7.1 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO35380.1 - 0.011 15.0 0.2 2.8 7.2 0.0 3.2 3 0 0 3 3 3 0 SHNi-TPR TPR_19 PF14559.1 ETO35380.1 - 0.013 15.7 1.4 2.7 8.3 0.3 3.3 1 1 1 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.27 ETO35381.1 - 3.1e-63 207.5 16.1 2.4e-12 46.2 0.0 8.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO35381.1 - 3.5e-08 32.1 0.4 1.7e-06 26.6 0.1 3.0 3 0 0 3 3 3 1 Cytochrome D1 heme domain Nup160 PF11715.3 ETO35381.1 - 3.1e-06 25.6 5.0 0.31 9.1 0.0 4.6 1 1 4 5 5 5 4 Nucleoporin Nup120/160 Kelch_2 PF07646.10 ETO35381.1 - 8.4e-06 25.3 0.9 0.18 11.6 0.0 4.5 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO35381.1 - 2.7e-05 23.8 4.6 0.017 14.8 0.0 5.3 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO35381.1 - 3.4e-05 23.8 11.7 0.27 11.4 0.1 6.7 6 2 1 7 7 7 2 Kelch motif Kelch_3 PF13415.1 ETO35381.1 - 7.5e-05 22.7 2.0 0.001 19.1 0.0 3.6 3 0 0 3 3 3 1 Galactose oxidase, central domain Nucleoporin_N PF08801.6 ETO35381.1 - 0.0013 17.5 10.7 0.33 9.6 0.0 4.7 2 1 2 4 4 4 1 Nup133 N terminal like Kelch_5 PF13854.1 ETO35381.1 - 0.0043 16.9 5.9 1.6 8.7 0.0 4.8 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.20 ETO35381.1 - 0.019 14.4 4.2 2.2 7.8 0.1 4.1 3 0 0 3 3 3 0 Kelch motif Resistin PF06954.6 ETO35381.1 - 0.065 13.5 4.1 7.6 6.8 0.0 4.9 2 1 4 6 6 6 0 Resistin Fanconi_A PF03511.9 ETO35382.1 - 2.5 7.9 4.7 6 6.7 0.0 2.7 2 1 1 3 3 3 0 Fanconi anaemia group A protein Metallophos PF00149.23 ETO35383.1 - 0.0034 16.8 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2259 PF10016.4 ETO35383.1 - 0.012 15.3 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Predicted secreted protein (DUF2259) WD40 PF00400.27 ETO35386.1 - 1.8e-14 52.9 0.5 1.5e-10 40.5 0.6 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO35386.1 - 5.1e-07 28.2 0.1 5.6e-07 28.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO35386.1 - 0.013 14.8 0.6 0.015 14.6 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4221) Nucleoporin_N PF08801.6 ETO35386.1 - 0.06 12.0 0.4 0.067 11.9 0.3 1.1 1 0 0 1 1 1 0 Nup133 N terminal like RNA_polI_A34 PF08208.6 ETO35387.1 - 0.00057 19.6 8.9 0.00069 19.3 5.9 1.4 1 1 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 Plasmodium_Vir PF05795.6 ETO35387.1 - 0.0045 16.2 7.0 0.0049 16.1 4.8 1.2 1 0 0 1 1 1 1 Plasmodium vivax Vir protein DUF1510 PF07423.6 ETO35387.1 - 0.81 9.0 12.2 1.1 8.5 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Raftlin PF15250.1 ETO35387.1 - 1.4 7.3 9.0 1.6 7.1 6.3 1.1 1 0 0 1 1 1 0 Raftlin BMP2K_C PF15282.1 ETO35387.1 - 5.9 6.9 7.9 1.5 8.9 3.4 1.5 2 0 0 2 2 2 0 BMP-2-inducible protein kinase C-terminus Hid1 PF12722.2 ETO35387.1 - 6.8 4.2 14.4 7.6 4.0 10.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ETF_QO PF05187.8 ETO35387.1 - 7.2 6.6 7.0 1.4 8.9 2.5 1.6 2 0 0 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase Plant_tran PF04827.9 ETO35388.1 - 0.0097 15.2 0.5 0.012 15.0 0.3 1.1 1 0 0 1 1 1 1 Plant transposon protein DUF1356 PF07092.7 ETO35388.1 - 0.02 14.1 0.4 0.02 14.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) Med2 PF11214.3 ETO35388.1 - 0.057 13.4 2.1 0.11 12.5 1.0 1.8 1 1 0 1 1 1 0 Mediator complex subunit 2 WD40 PF00400.27 ETO35389.1 - 1.4e-29 100.8 20.1 6.3e-10 38.5 1.2 5.6 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO35389.1 - 6.9e-06 24.4 2.4 0.018 13.2 0.2 3.8 1 1 2 3 3 3 3 Nucleoporin Nup120/160 CPSF_A PF03178.10 ETO35389.1 - 0.037 13.1 0.0 0.66 9.0 0.0 2.2 2 0 0 2 2 2 0 CPSF A subunit region VWA PF00092.23 ETO35389.1 - 0.045 13.4 0.1 0.088 12.5 0.1 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain ExbD PF02472.11 ETO35390.1 - 0.027 14.4 2.9 0.031 14.2 1.3 1.8 1 1 1 2 2 2 0 Biopolymer transport protein ExbD/TolR SID-1_RNA_chan PF13965.1 ETO35390.1 - 0.095 10.8 7.8 0.11 10.6 5.4 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 HBS1_N PF08938.5 ETO35390.1 - 0.3 11.2 3.5 2.1 8.5 0.1 2.5 2 0 0 2 2 2 0 HBS1 N-terminus Iron_permease PF04120.7 ETO35390.1 - 0.52 9.9 5.4 0.54 9.8 2.9 1.6 1 1 0 1 1 1 0 Low affinity iron permease MerR-DNA-bind PF09278.6 ETO35390.1 - 2 8.8 4.5 1.5 9.2 0.1 2.5 3 0 0 3 3 3 0 MerR, DNA binding Ras PF00071.17 ETO35391.1 - 4.3e-46 156.2 4.8 5.8e-43 146.0 2.9 3.4 2 1 0 2 2 2 1 Ras family Miro PF08477.8 ETO35391.1 - 6.3e-17 62.1 0.2 8.7e-16 58.4 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO35391.1 - 6.9e-16 57.9 3.2 2.2e-15 56.3 0.8 2.5 2 1 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO35391.1 - 3.5e-07 29.8 0.3 1.4e-06 27.9 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 ETO35391.1 - 3.5e-05 23.0 0.1 3.5e-05 23.0 0.1 2.2 1 1 1 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 ETO35391.1 - 0.0013 18.7 0.0 0.0033 17.3 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 ETO35391.1 - 0.079 13.0 0.1 0.32 11.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain zf-C2H2 PF00096.21 ETO35392.1 - 1.4e-09 37.7 9.8 1.3e-05 25.2 1.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETO35392.1 - 7.7e-07 29.0 11.8 0.001 19.2 1.2 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETO35392.1 - 0.0025 18.0 16.6 0.083 13.2 3.1 3.9 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 ETO35392.1 - 0.0026 17.5 4.7 0.0099 15.7 0.5 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 ETO35392.1 - 0.0031 17.6 9.4 0.23 11.6 0.2 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 ETO35392.1 - 0.073 13.2 4.4 2 8.6 3.1 2.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 ETO35392.1 - 0.099 12.3 0.3 0.099 12.3 0.2 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.1 ETO35392.1 - 0.43 10.8 7.4 0.24 11.7 0.6 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-met PF12874.2 ETO35392.1 - 0.87 9.8 5.2 1.2 9.4 0.2 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Elf1 PF05129.8 ETO35392.1 - 1.5 8.5 6.3 6 6.6 3.5 2.3 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Cpn60_TCP1 PF00118.19 ETO35394.1 - 8.2e-51 173.1 0.8 9.7e-51 172.8 0.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ank_2 PF12796.2 ETO35395.1 - 0.0018 18.5 0.0 0.0026 18.0 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Trypan_PARP PF05887.6 ETO35396.1 - 0.001 18.9 1.3 0.001 18.9 0.9 1.4 1 1 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) PAT1 PF09770.4 ETO35396.1 - 0.009 14.3 35.0 0.0088 14.3 24.3 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Tmemb_9 PF05434.6 ETO35396.1 - 1.9 8.2 12.3 0.15 11.8 4.6 2.0 1 1 1 2 2 2 0 TMEM9 Borrelia_P83 PF05262.6 ETO35396.1 - 2.1 6.4 17.8 2.3 6.3 12.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein SID-1_RNA_chan PF13965.1 ETO35396.1 - 3.9 5.5 9.9 2.5 6.1 5.9 1.3 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4480 PF13715.1 ETO35396.1 - 4.1 7.5 12.2 0.16 12.0 0.2 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4480) Herpes_DNAp_acc PF04929.7 ETO35396.1 - 5.9 5.7 15.6 9.5 5.0 10.8 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor YjgP_YjgQ PF03739.9 ETO35396.1 - 7.1 5.2 8.1 8.4 5.0 5.6 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF4131 PF13567.1 ETO35397.1 - 1.1 8.6 20.8 0.45 9.8 1.7 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Gpi1 PF05024.10 ETO35398.1 - 8.1e-31 107.1 5.7 8.1e-31 107.1 4.0 2.1 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) Pkinase PF00069.20 ETO35399.1 - 2.9e-06 26.6 0.0 4.2e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO35399.1 - 5.3e-06 25.6 0.0 7.9e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Exo_endo_phos_2 PF14529.1 ETO35399.1 - 0.018 14.6 1.2 0.036 13.6 0.8 1.5 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase DUF3953 PF13129.1 ETO35399.1 - 0.023 14.3 2.8 0.3 10.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3953) WD40 PF00400.27 ETO35401.1 - 2e-09 36.9 10.8 0.0011 18.7 0.1 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat PH PF00169.24 ETO35402.1 - 1.9e-05 24.8 0.0 5.9e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 PH domain RhoGEF PF00621.15 ETO35402.1 - 0.0031 17.3 0.1 0.0071 16.2 0.1 1.5 1 0 0 1 1 1 1 RhoGEF domain Peptidase_M13_N PF05649.8 ETO35402.1 - 0.016 14.2 0.3 0.027 13.5 0.2 1.3 1 0 0 1 1 1 0 Peptidase family M13 DUF3723 PF12520.3 ETO35405.1 - 0.026 13.0 0.1 0.033 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3723) SAG PF04092.8 ETO35405.1 - 0.064 13.6 1.4 0.086 13.2 1.0 1.2 1 0 0 1 1 1 0 SRS domain Mem_trans PF03547.13 ETO35405.1 - 0.11 10.7 0.3 0.12 10.6 0.2 1.1 1 0 0 1 1 1 0 Membrane transport protein Dexa_ind PF15198.1 ETO35405.1 - 0.89 9.5 3.2 0.9 9.4 1.6 1.6 1 1 0 1 1 1 0 Dexamethasone-induced YtfJ_HI0045 PF09695.5 ETO35406.1 - 0.067 12.5 0.0 0.48 9.7 0.0 2.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (YtfJ_HI0045) WD40 PF00400.27 ETO35407.1 - 1.6e-07 30.9 0.0 7.2e-07 28.8 0.0 1.9 2 0 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO35407.1 - 0.12 10.5 0.0 0.12 10.4 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 HAD PF12710.2 ETO35407.1 - 0.13 12.4 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Cys_rich_VLP PF14194.1 ETO35408.1 - 2.3 8.0 7.5 0.56 9.9 0.6 2.3 2 0 0 2 2 2 0 Cysteine-rich VLP WD40 PF00400.27 ETO35409.1 - 2.3e-157 505.9 55.0 2.2e-12 46.3 0.3 16.2 16 0 0 16 16 16 16 WD domain, G-beta repeat Nup160 PF11715.3 ETO35409.1 - 1.1e-13 50.2 27.4 0.046 11.8 0.2 12.1 2 2 9 13 13 13 8 Nucleoporin Nup120/160 DUF1258 PF06869.7 ETO35409.1 - 5e-10 38.9 7.2 0.36 9.8 0.1 7.7 2 2 5 8 8 8 4 Protein of unknown function (DUF1258) PQQ_2 PF13360.1 ETO35409.1 - 1.2e-08 34.7 3.5 0.0003 20.3 0.2 4.3 2 1 1 3 3 3 2 PQQ-like domain Mid2 PF04478.7 ETO35409.1 - 1.9e-07 30.6 13.4 1.5 8.2 0.1 8.1 5 3 3 8 8 8 2 Mid2 like cell wall stress sensor PD40 PF07676.7 ETO35409.1 - 2.2e-06 27.1 12.9 1 9.1 0.0 9.0 10 0 0 10 10 10 2 WD40-like Beta Propeller Repeat Pentapeptide_4 PF13599.1 ETO35409.1 - 6.3e-06 25.9 0.5 1.5e-05 24.6 0.3 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETO35409.1 - 2.5e-05 23.4 0.5 5.5e-05 22.3 0.4 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) DUF1938 PF09153.5 ETO35409.1 - 9.4e-05 22.1 4.0 0.36 10.6 0.1 5.0 4 2 2 6 6 6 2 Domain of unknown function (DUF1938) Pentapeptide_3 PF13576.1 ETO35409.1 - 0.00047 19.9 0.3 0.0016 18.2 0.2 1.9 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) NYD-SP28_assoc PF14775.1 ETO35409.1 - 3.5 7.4 20.9 65 3.3 0.0 10.1 15 0 0 15 15 15 0 Sperm tail C-terminal domain DUF2207 PF09972.4 ETO35410.1 - 0.014 13.9 1.4 0.26 9.8 0.2 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Inhibitor_I69 PF13734.1 ETO35410.1 - 0.064 13.3 0.1 0.32 11.1 0.1 2.1 2 0 0 2 2 2 0 Spi protease inhibitor ELFV_dehydrog PF00208.16 ETO35411.1 - 2.3e-21 76.4 0.2 3.3e-21 75.9 0.1 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase WHEP-TRS PF00458.15 ETO35412.1 - 0.0038 16.8 2.4 0.011 15.3 0.0 2.5 2 0 0 2 2 2 1 WHEP-TRS domain MDM1 PF15501.1 ETO35415.1 - 0.39 9.6 4.5 0.54 9.1 3.1 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 ABC_tran PF00005.22 ETO35416.1 - 5.5e-08 33.1 0.0 1.1e-07 32.1 0.0 1.5 2 0 0 2 2 2 1 ABC transporter MmlI PF09448.5 ETO35416.1 - 0.066 12.9 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Methylmuconolactone methyl-isomerase SMC_N PF02463.14 ETO35416.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Aminotran_5 PF00266.14 ETO35417.1 - 1e-16 60.7 0.0 8.8e-16 57.6 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V MT0933_antitox PF14013.1 ETO35419.1 - 0.086 12.9 0.8 9.3 6.4 0.0 3.4 3 1 0 3 3 3 0 MT0933-like antitoxin protein FragX_IP PF05994.6 ETO35419.1 - 0.22 9.2 0.0 0.82 7.3 0.0 1.7 2 0 0 2 2 2 0 Cytoplasmic Fragile-X interacting family Wax2_C PF12076.3 ETO35420.1 - 0.047 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 WAX2 C-terminal domain Rsm22 PF09243.5 ETO35421.1 - 0.073 12.0 0.3 0.073 12.0 0.2 1.7 2 0 0 2 2 2 0 Mitochondrial small ribosomal subunit Rsm22 MutS_III PF05192.13 ETO35422.1 - 1.8e-09 37.6 0.1 2.1e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 ETO35422.1 - 5.3e-06 26.5 0.1 2e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 MutS family domain IV Arc_PepC PF06819.6 ETO35422.1 - 0.12 12.3 1.5 0.22 11.4 1.0 1.5 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain MutS_V PF00488.16 ETO35423.1 - 7.8e-88 293.8 0.5 1.9e-87 292.5 0.2 1.6 1 1 1 2 2 2 1 MutS domain V Kinesin PF00225.18 ETO35424.1 - 3.5e-12 45.6 0.9 4.2e-12 45.4 0.4 1.4 1 1 1 2 2 2 1 Kinesin motor domain YqzE PF14038.1 ETO35425.1 - 0.083 12.6 0.2 0.16 11.7 0.2 1.5 1 1 0 1 1 1 0 YqzE-like protein DUF3959 PF13105.1 ETO35426.1 - 0.012 14.9 0.1 0.021 14.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) MutS_III PF05192.13 ETO35427.1 - 2.7e-18 66.4 0.0 3.5e-17 62.8 0.0 2.3 2 1 0 2 2 2 1 MutS domain III MutS_II PF05188.12 ETO35427.1 - 4e-07 30.1 0.1 7e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 MutS domain II MutS_I PF01624.15 ETO35427.1 - 1.8e-05 24.7 0.3 0.00012 22.0 0.0 2.3 2 1 0 2 2 2 1 MutS domain I Fea1 PF07692.6 ETO35427.1 - 0.035 12.9 0.1 0.061 12.1 0.0 1.3 1 0 0 1 1 1 0 Low iron-inducible periplasmic protein DUF796 PF05638.7 ETO35427.1 - 0.059 13.3 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF796) WD40 PF00400.27 ETO35428.1 - 3.2e-86 280.4 32.1 7.3e-12 44.6 0.0 10.1 10 0 0 10 10 10 10 WD domain, G-beta repeat Nup160 PF11715.3 ETO35428.1 - 4.1e-14 51.6 12.2 0.28 9.2 0.0 8.6 1 1 5 6 6 6 6 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO35428.1 - 8e-06 25.4 0.2 0.011 15.2 0.0 4.0 1 1 3 4 4 4 2 PQQ-like domain DPPIV_N PF00930.16 ETO35428.1 - 1.5e-05 23.7 0.8 0.022 13.3 0.0 3.9 2 2 1 4 4 4 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nbas_N PF15492.1 ETO35428.1 - 4.4e-05 22.7 7.5 0.27 10.2 0.0 5.4 2 2 3 7 7 7 2 Neuroblastoma-amplified sequence, N terminal DUF1938 PF09153.5 ETO35428.1 - 0.00037 20.2 2.0 0.12 12.1 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF1938) PD40 PF07676.7 ETO35428.1 - 0.001 18.6 15.7 4.7 6.9 0.0 6.6 8 0 0 8 8 8 3 WD40-like Beta Propeller Repeat Ricin_B_lectin PF00652.17 ETO35428.1 - 0.0011 18.9 4.3 12 5.9 0.1 4.6 1 1 2 4 4 4 0 Ricin-type beta-trefoil lectin domain Coatomer_WDAD PF04053.9 ETO35428.1 - 0.0017 17.2 4.8 0.39 9.4 0.2 3.1 1 1 1 3 3 3 2 Coatomer WD associated region Mid2 PF04478.7 ETO35428.1 - 0.0018 17.7 7.1 1.4 8.2 0.0 5.0 2 2 4 6 6 6 2 Mid2 like cell wall stress sensor Pectate_lyase22 PF14583.1 ETO35428.1 - 0.032 12.6 0.1 1.9 6.8 0.0 3.0 2 2 0 3 3 3 0 Oligogalacturonate lyase YqaJ PF09588.5 ETO35428.1 - 0.1 12.5 0.4 3.2 7.7 0.0 2.8 2 2 0 2 2 2 0 YqaJ-like viral recombinase domain WD40 PF00400.27 ETO35430.1 - 2.6e-30 103.1 15.6 2.4e-11 43.0 0.1 4.0 3 1 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO35430.1 - 8.9e-05 20.8 0.4 0.093 10.8 0.0 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO35430.1 - 0.00014 20.7 7.5 0.73 8.5 2.0 3.0 2 1 1 3 3 3 3 Nup133 N terminal like DUF3601 PF12208.3 ETO35430.1 - 0.0099 15.7 0.0 2.5 8.1 0.0 2.6 3 0 0 3 3 3 2 Domain of unknown function (DUF3601) KduI PF04962.7 ETO35430.1 - 0.15 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 KduI/IolB family WD40 PF00400.27 ETO35431.1 - 6.2e-31 105.1 11.0 8.2e-12 44.5 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO35431.1 - 2.4e-07 29.2 2.0 0.019 13.1 0.0 3.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 DUF3601 PF12208.3 ETO35431.1 - 0.021 14.7 1.8 0.77 9.7 0.0 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF3601) DUF3011 PF11218.3 ETO35431.1 - 0.031 14.0 0.2 0.056 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3011) MCM2_N PF12619.3 ETO35432.1 - 0.52 10.2 4.4 0.86 9.5 3.0 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 WD40 PF00400.27 ETO35433.1 - 3.1e-65 213.8 27.9 4.9e-12 45.2 0.0 7.3 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO35433.1 - 2e-11 42.7 8.3 0.0021 16.2 0.3 5.3 1 1 5 6 6 6 4 Nucleoporin Nup120/160 DUF1900 PF08954.6 ETO35433.1 - 1.1e-05 25.0 0.3 1.4 8.4 0.0 5.3 3 2 3 6 6 6 1 Domain of unknown function (DUF1900) DUF3601 PF12208.3 ETO35433.1 - 0.0068 16.3 0.0 0.029 14.2 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3601) Methyltransf_25 PF13649.1 ETO35433.1 - 0.022 15.0 0.1 5.7 7.3 0.0 3.0 3 0 0 3 3 3 0 Methyltransferase domain COX5B PF01215.14 ETO35433.1 - 0.061 12.9 0.2 5.2 6.7 0.0 2.6 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Vb USP7_C2 PF14533.1 ETO35433.1 - 0.12 11.7 2.3 18 4.7 0.1 4.2 2 1 2 4 4 4 0 Ubiquitin-specific protease C-terminal Archaeal_AmoA PF12942.2 ETO35433.1 - 0.15 11.7 0.0 0.33 10.7 0.0 1.5 2 0 0 2 2 2 0 Archaeal ammonia monooxygenase subunit A (AmoA) NAD_Gly3P_dh_N PF01210.18 ETO35433.1 - 0.77 9.4 5.0 6.9 6.3 0.1 3.8 2 2 3 5 5 5 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus WD40 PF00400.27 ETO35434.1 - 1.2e-18 66.2 2.2 1.5e-10 40.5 0.0 3.2 3 1 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO35434.1 - 0.012 13.7 0.1 1.2 7.2 0.0 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO35434.1 - 0.034 12.8 2.6 1.4 7.5 0.0 2.7 1 1 2 3 3 3 0 Nup133 N terminal like WD40 PF00400.27 ETO35435.1 - 4.5e-65 213.3 21.5 3.3e-11 42.6 0.7 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO35435.1 - 5e-14 51.3 3.9 0.0032 15.6 0.1 5.3 1 1 3 5 5 5 5 Nucleoporin Nup120/160 SNAPc_SNAP43 PF09808.4 ETO35435.1 - 0.0067 16.1 0.3 0.015 14.9 0.2 1.6 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 HAD PF12710.2 ETO35435.1 - 0.018 15.2 5.3 1.4 9.0 0.0 3.1 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF1914 PF08932.5 ETO35435.1 - 7.8 6.5 9.8 1.8 8.5 0.1 4.1 3 2 1 4 4 4 0 Domain of unknown function (DUF1914) WD40 PF00400.27 ETO35436.1 - 1.8e-36 122.7 13.9 3.4e-12 45.7 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO35436.1 - 1.4e-07 30.0 0.6 0.015 13.4 0.2 3.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 DUF4513 PF14983.1 ETO35436.1 - 0.11 12.3 0.3 0.11 12.3 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4513) ATG16 PF08614.6 ETO35436.1 - 2 8.1 21.0 3.9 7.2 14.6 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) WD40 PF00400.27 ETO35438.1 - 5.8e-60 197.1 17.9 8.7e-11 41.2 0.8 6.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO35438.1 - 2.7e-10 39.0 5.6 0.012 13.7 0.0 4.7 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Ectoine_synth PF06339.7 ETO35438.1 - 0.042 13.7 0.7 11 6.0 0.0 2.9 3 0 0 3 3 3 0 Ectoine synthase Kelch_1 PF01344.20 ETO35439.1 - 1.8e-07 30.5 0.3 1.6e-05 24.3 0.0 3.3 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 ETO35439.1 - 0.00016 21.6 0.1 0.7 10.1 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 ETO35439.1 - 0.0059 16.5 2.7 0.21 11.5 0.1 3.4 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 ETO35439.1 - 0.012 15.3 0.0 0.53 10.0 0.0 3.2 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO35439.1 - 0.025 14.3 1.7 2.6 7.9 0.0 3.7 4 0 0 4 4 4 0 Kelch motif FANCI_S1 PF14675.1 ETO35440.1 - 0.016 14.5 0.2 0.021 14.1 0.1 1.1 1 0 0 1 1 1 0 FANCI solenoid 1 Pkinase PF00069.20 ETO35441.1 - 0.0011 18.1 0.8 0.0014 17.8 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain SET PF00856.23 ETO35442.1 - 0.00058 20.2 0.4 0.003 17.8 0.3 2.0 1 1 0 1 1 1 1 SET domain Pkinase PF00069.20 ETO35443.1 - 5.9e-56 189.4 0.0 1.1e-55 188.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO35443.1 - 3.9e-23 81.8 0.0 7e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 ETO35443.1 - 1e-18 65.1 5.5 1.4e-05 24.0 0.0 4.7 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 ETO35443.1 - 1.4e-13 50.7 11.9 2e-07 31.0 2.4 3.1 3 1 0 3 3 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO35443.1 - 3.3e-10 38.9 12.7 0.047 13.5 0.1 5.5 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 ETO35443.1 - 4e-10 39.1 6.7 0.029 14.0 0.1 4.8 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 ETO35443.1 - 1.3e-07 30.6 14.0 0.00073 18.7 0.1 4.6 5 0 0 5 5 5 3 EF hand APH PF01636.18 ETO35443.1 - 7.1e-06 25.9 0.1 1.3e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 ETO35443.1 - 0.00015 21.1 0.2 0.00015 21.1 0.1 1.7 2 0 0 2 2 2 1 RIO1 family YrbL-PhoP_reg PF10707.4 ETO35443.1 - 0.00096 18.5 0.0 0.0023 17.3 0.0 1.6 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 ETO35443.1 - 0.00099 18.7 0.0 0.0027 17.3 0.0 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 ETO35443.1 - 0.0025 16.6 0.3 0.0048 15.7 0.2 1.4 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.9 ETO35443.1 - 0.0074 15.3 0.1 0.015 14.3 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_4 PF12763.2 ETO35443.1 - 0.029 14.1 1.0 0.25 11.0 0.1 2.3 1 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 ETO35443.1 - 0.29 11.1 4.1 0.92 9.5 0.2 3.1 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Amidohydro_2 PF04909.9 ETO35444.1 - 1.1e-18 67.8 0.0 1.7e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Tmemb_55A PF09788.4 ETO35444.1 - 0.14 11.2 0.1 0.24 10.5 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 55A TatD_DNase PF01026.16 ETO35444.1 - 0.15 11.1 0.0 0.76 8.9 0.0 1.9 2 0 0 2 2 2 0 TatD related DNase ODV-E18 PF10717.4 ETO35444.1 - 1.3 8.5 4.0 3.1 7.2 2.8 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 RabGAP-TBC PF00566.13 ETO35445.1 - 5.4e-40 137.1 3.5 5.4e-40 137.1 2.4 3.6 2 2 1 3 3 3 1 Rab-GTPase-TBC domain RCC1 PF00415.13 ETO35445.1 - 1.8e-12 47.2 2.5 7.3e-09 35.7 0.3 2.6 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO35445.1 - 3.9e-08 32.6 3.8 3.9e-08 32.6 2.6 2.1 2 0 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat Sporozoite_P67 PF05642.6 ETO35445.1 - 6.7 4.4 14.1 13 3.5 9.7 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PRA1 PF03208.14 ETO35446.1 - 3e-05 23.3 2.4 4.2e-05 22.9 1.7 1.1 1 0 0 1 1 1 1 PRA1 family protein NhaB PF06450.7 ETO35446.1 - 0.00045 18.9 0.7 0.00056 18.6 0.5 1.0 1 0 0 1 1 1 1 Bacterial Na+/H+ antiporter B (NhaB) UbiA PF01040.13 ETO35446.1 - 0.0076 15.5 2.3 0.0093 15.2 1.6 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Vps55 PF04133.9 ETO35446.1 - 0.032 13.9 1.3 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 Vacuolar protein sorting 55 RNA_pol_Rpb2_1 PF04563.10 ETO35446.1 - 0.035 13.0 0.0 0.045 12.6 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase beta subunit TraX PF05857.6 ETO35446.1 - 0.095 12.3 5.7 0.11 12.0 3.9 1.1 1 0 0 1 1 1 0 TraX protein Glyco_transf_22 PF03901.12 ETO35446.1 - 0.34 9.8 4.8 0.43 9.5 3.3 1.1 1 0 0 1 1 1 0 Alg9-like mannosyltransferase family DUF4131 PF13567.1 ETO35446.1 - 0.44 9.9 2.1 0.59 9.5 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) O-antigen_lig PF13425.1 ETO35446.1 - 0.78 9.7 12.0 1.4 8.9 8.4 1.3 1 1 0 1 1 1 0 O-antigen ligase like membrane protein DUF4083 PF13314.1 ETO35446.1 - 4.7 7.1 7.9 0.2 11.5 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) DUF4064 PF13273.1 ETO35447.1 - 0.023 14.7 0.9 0.46 10.6 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF4064) VirB3 PF05101.8 ETO35447.1 - 0.26 11.3 3.1 0.19 11.6 1.0 1.6 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein DUF3816 PF12822.2 ETO35447.1 - 0.26 11.1 4.0 1.3 8.8 1.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3816) Kelch_6 PF13964.1 ETO35448.1 - 1.3e-10 40.9 5.8 0.0061 16.6 0.0 4.8 4 1 1 5 5 5 3 Kelch motif Kelch_5 PF13854.1 ETO35448.1 - 2.6e-10 40.0 3.0 0.021 14.7 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 ETO35448.1 - 2.3e-09 36.6 5.0 0.0027 17.2 0.0 4.0 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.10 ETO35448.1 - 5.4e-07 29.1 7.5 0.00049 19.7 0.0 4.4 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO35448.1 - 6.2e-06 25.8 3.6 0.0005 19.7 0.0 4.0 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO35448.1 - 0.036 14.2 0.0 29 4.9 0.0 4.2 4 0 0 4 4 4 0 Galactose oxidase, central domain WD40 PF00400.27 ETO35449.1 - 6e-23 79.8 6.6 1.3e-09 37.5 0.0 6.6 6 2 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 ETO35449.1 - 0.00027 20.7 0.1 1.2 8.8 0.0 3.8 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO35449.1 - 0.00031 19.0 0.1 0.93 7.5 0.0 3.0 2 1 1 3 3 3 2 Nucleoporin Nup120/160 PD40 PF07676.7 ETO35449.1 - 0.0006 19.4 0.4 2.3 7.9 0.0 4.4 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO35449.1 - 0.0042 15.8 0.9 0.66 8.6 0.1 2.5 1 1 1 2 2 2 2 Nup133 N terminal like PQQ_2 PF13360.1 ETO35449.1 - 0.0081 15.6 0.0 1 8.7 0.0 2.9 3 1 0 3 3 3 1 PQQ-like domain Mid2 PF04478.7 ETO35449.1 - 0.0087 15.4 0.6 6.9 6.0 0.0 3.0 1 1 2 3 3 3 2 Mid2 like cell wall stress sensor Proteasome_A_N PF10584.4 ETO35449.1 - 0.28 10.5 4.1 3.3 7.1 0.0 3.4 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature DnaJ PF00226.26 ETO35450.1 - 6.3e-15 54.6 0.9 9e-15 54.1 0.6 1.2 1 0 0 1 1 1 1 DnaJ domain CUE PF02845.11 ETO35451.1 - 0.0075 15.7 0.1 0.019 14.4 0.1 1.7 1 0 0 1 1 1 1 CUE domain PUB PF09409.5 ETO35451.1 - 0.017 14.8 4.3 0.11 12.2 0.5 3.3 2 1 0 3 3 3 0 PUB domain DnaG_DnaB_bind PF08278.6 ETO35451.1 - 0.059 13.6 1.5 0.1 12.8 1.1 1.4 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding PCI PF01399.22 ETO35451.1 - 0.24 11.7 2.7 0.45 10.8 0.6 2.3 1 1 1 2 2 2 0 PCI domain Kelch_5 PF13854.1 ETO35452.1 - 0.11 12.5 0.1 16 5.5 0.0 2.3 2 0 0 2 2 2 0 Kelch motif Copper-bind PF00127.15 ETO35452.1 - 0.39 10.9 2.4 0.55 10.4 0.2 2.0 1 1 1 2 2 2 0 Copper binding proteins, plastocyanin/azurin family DS PF01916.12 ETO35453.1 - 0.0045 16.1 0.0 0.0063 15.6 0.0 1.1 1 0 0 1 1 1 1 Deoxyhypusine synthase TPR_12 PF13424.1 ETO35454.1 - 1e-14 54.2 0.0 1.7e-06 27.8 0.0 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO35454.1 - 1.2e-05 24.8 0.0 0.022 14.4 0.0 2.1 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETO35454.1 - 5.4e-05 22.6 0.7 0.29 10.7 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO35454.1 - 7.9e-05 22.4 0.0 0.023 14.6 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO35454.1 - 0.0002 20.9 0.0 0.92 9.4 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO35454.1 - 0.004 16.8 1.7 0.24 11.2 1.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 ETO35454.1 - 0.0058 16.4 0.1 0.015 15.1 0.1 1.7 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_2 PF07719.12 ETO35454.1 - 0.0071 16.1 0.2 2.7 8.1 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO35454.1 - 0.013 14.6 0.0 0.17 11.1 0.0 2.1 2 0 0 2 2 2 0 SHNi-TPR Kelch_1 PF01344.20 ETO35456.1 - 5.3e-06 25.8 0.2 0.00097 18.6 0.1 2.2 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 ETO35456.1 - 1.7e-05 24.4 0.0 0.035 13.8 0.0 2.3 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO35456.1 - 0.00023 20.7 0.6 0.34 10.7 0.1 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.1 ETO35456.1 - 0.0011 19.0 0.1 0.31 11.2 0.0 2.3 1 1 1 2 2 2 2 Kelch motif Kelch_3 PF13415.1 ETO35456.1 - 0.044 13.9 0.0 0.26 11.5 0.0 2.0 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO35456.1 - 0.082 12.8 0.0 0.94 9.5 0.0 2.2 2 0 0 2 2 2 0 Kelch motif WD40 PF00400.27 ETO35457.1 - 5.6e-05 22.8 1.6 5.6e-05 22.8 1.1 1.6 2 1 0 2 2 2 1 WD domain, G-beta repeat Corona_6B_7B PF03262.8 ETO35457.1 - 0.027 13.7 0.2 0.035 13.3 0.1 1.2 1 0 0 1 1 1 0 Coronavirus 6B/7B protein DUF2207 PF09972.4 ETO35458.1 - 0.059 11.9 5.2 0.089 11.3 3.6 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) NPR3 PF03666.8 ETO35458.1 - 0.06 11.8 12.1 0.079 11.4 8.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 LMBR1 PF04791.11 ETO35458.1 - 0.14 10.6 3.6 0.18 10.3 2.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein IncA PF04156.9 ETO35458.1 - 0.19 11.2 4.1 0.24 10.9 2.8 1.3 1 0 0 1 1 1 0 IncA protein RNA_pol_Rpb1_5 PF04998.12 ETO35458.1 - 0.96 8.6 7.7 1.1 8.4 5.4 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Zip PF02535.17 ETO35458.1 - 1.2 8.1 4.6 1.1 8.1 2.9 1.3 1 1 0 1 1 1 0 ZIP Zinc transporter SpoIIP PF07454.6 ETO35458.1 - 1.8 7.6 13.2 0.41 9.7 6.8 1.7 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF2661 PF10860.3 ETO35458.1 - 2.6 8.2 6.1 5.6 7.1 4.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2661) AAA_11 PF13086.1 ETO35458.1 - 5.3 6.5 11.3 7.3 6.0 7.9 1.2 1 0 0 1 1 1 0 AAA domain DUF912 PF06024.7 ETO35458.1 - 8.5 6.4 8.9 7.8 6.6 4.0 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Cation_ATPase_C PF00689.16 ETO35459.1 - 1.4e-39 135.4 7.0 2.5e-39 134.6 4.8 1.4 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 ETO35459.1 - 9.2e-26 91.5 0.0 3.9e-24 86.2 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETO35459.1 - 4.9e-15 56.2 0.3 9.5e-15 55.2 0.2 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETO35459.1 - 3.7e-14 52.4 0.0 7.5e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 ETO35459.1 - 4.3e-05 23.2 1.2 0.013 15.0 0.5 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 ETO35459.1 - 0.093 12.9 0.0 1.4 9.1 0.0 2.3 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Methyltransf_31 PF13847.1 ETO35460.1 - 2.7e-26 91.9 0.0 5.4e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO35460.1 - 6.4e-11 42.8 0.0 1.1e-10 42.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETO35460.1 - 1.9e-10 41.1 0.0 4.2e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETO35460.1 - 3.3e-08 32.9 0.0 5.3e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 ETO35460.1 - 1e-07 31.8 0.0 1.6e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETO35460.1 - 3.9e-07 30.3 0.0 2.8e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO35460.1 - 1.3e-06 28.7 0.0 2.9e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETO35460.1 - 5.8e-06 26.3 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 ETO35460.1 - 1.9e-05 24.3 0.1 3.5e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.14 ETO35460.1 - 0.0027 17.7 0.1 0.0069 16.3 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase PrmA PF06325.8 ETO35460.1 - 0.0051 15.9 0.0 0.0084 15.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DUF2670 PF10875.3 ETO35460.1 - 0.0065 16.4 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2670) DOT1 PF08123.8 ETO35460.1 - 0.018 14.3 0.2 0.039 13.2 0.0 1.6 2 0 0 2 2 2 0 Histone methylation protein DOT1 Methyltransf_8 PF05148.10 ETO35460.1 - 0.069 12.7 0.1 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_32 PF13679.1 ETO35460.1 - 0.074 12.7 0.1 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain ABC2_membrane PF01061.19 ETO35461.1 - 0.021 13.9 0.3 0.021 13.9 0.2 2.9 3 0 0 3 3 3 0 ABC-2 type transporter PDR_CDR PF06422.7 ETO35461.1 - 0.044 13.4 0.2 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 CDR ABC transporter DUF2614 PF11023.3 ETO35461.1 - 2.6 7.8 5.0 1.8 8.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2614) WD40 PF00400.27 ETO35462.1 - 1e-42 142.5 20.2 4.2e-11 42.2 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO35462.1 - 6.7e-06 24.5 4.1 0.00046 18.4 0.3 3.4 2 2 0 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO35462.1 - 0.00032 20.2 3.1 0.19 11.1 0.1 2.4 1 1 0 1 1 1 1 PQQ-like domain Hira PF07569.6 ETO35462.1 - 0.0053 15.9 6.0 7.7 5.6 0.0 4.4 2 2 3 5 5 5 2 TUP1-like enhancer of split Cytochrom_D1 PF02239.11 ETO35462.1 - 0.027 12.7 0.0 1.9 6.6 0.0 2.5 2 1 0 3 3 3 0 Cytochrome D1 heme domain PQQ PF01011.16 ETO35462.1 - 0.058 12.9 1.4 3.7 7.2 0.2 3.1 3 0 0 3 3 3 0 PQQ enzyme repeat PDCD2_C PF04194.8 ETO35463.1 - 9.9e-25 87.0 17.9 1.1e-21 77.1 12.4 3.2 1 1 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain DUF4215 PF13948.1 ETO35463.1 - 0.16 12.1 0.1 0.16 12.1 0.1 4.1 5 0 0 5 5 5 0 Domain of unknown function (DUF4215) Transket_pyr PF02779.19 ETO35464.1 - 1.5e-37 128.7 0.0 2.5e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_N PF00456.16 ETO35464.1 - 9.8e-13 47.6 0.0 1.4e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.15 ETO35464.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.6 1 1 0 1 1 1 0 Transketolase, C-terminal domain DUF720 PF05302.6 ETO35465.1 - 0.048 13.4 1.9 0.79 9.4 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF720) DUF1625 PF07787.7 ETO35465.1 - 0.3 10.2 5.7 0.42 9.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1625) WD40 PF00400.27 ETO35466.1 - 9.1e-33 110.9 7.6 1.1e-10 40.9 0.2 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO35466.1 - 6.9e-06 24.4 0.3 0.025 12.7 0.1 2.6 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Antirestrict PF03230.8 ETO35467.1 - 0.015 15.2 0.2 1.4 8.9 0.0 3.0 2 1 1 3 3 3 0 Antirestriction protein A2M_recep PF07677.9 ETO35467.1 - 0.02 15.0 0.7 0.047 13.8 0.5 1.7 1 0 0 1 1 1 0 A-macroglobulin receptor DUF2418 PF10332.4 ETO35467.1 - 0.29 11.4 0.1 0.29 11.4 0.0 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF2418) NACHT PF05729.7 ETO35468.1 - 6.3e-20 71.4 0.0 3.2e-18 65.9 0.0 3.4 3 0 0 3 3 3 1 NACHT domain HEAT_2 PF13646.1 ETO35468.1 - 3.2e-12 46.5 0.0 1.9e-05 24.8 0.0 5.5 4 2 3 7 7 7 5 HEAT repeats HEAT PF02985.17 ETO35468.1 - 6.3e-10 38.2 0.1 0.19 11.8 0.0 7.0 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 ETO35468.1 - 1.8e-05 25.0 0.0 1.9 9.0 0.0 5.2 5 1 1 6 6 6 1 HEAT-like repeat Ank_2 PF12796.2 ETO35468.1 - 0.0018 18.5 0.1 0.028 14.7 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO35468.1 - 0.0037 17.4 0.1 0.024 14.9 0.1 2.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 ETO35468.1 - 0.0048 16.6 0.8 0.057 13.2 0.0 3.2 4 0 0 4 4 4 1 Ankyrin repeat AAA_16 PF13191.1 ETO35468.1 - 0.0067 16.4 0.0 0.022 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain HIPIP PF01355.12 ETO35469.1 - 0.051 13.6 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 High potential iron-sulfur protein ER PF01133.12 ETO35470.1 - 0.041 13.5 0.6 0.075 12.7 0.3 1.5 2 0 0 2 2 2 0 Enhancer of rudimentary Lig_chan PF00060.21 ETO35470.1 - 0.058 13.1 0.5 0.13 11.9 0.4 1.6 1 0 0 1 1 1 0 Ligand-gated ion channel DUF788 PF05620.6 ETO35470.1 - 8.7 6.1 7.4 17 5.2 1.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF788) WD40 PF00400.27 ETO35471.1 - 0.00084 19.1 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 WD domain, G-beta repeat PfUIS3 PF11567.3 ETO35471.1 - 0.016 15.3 1.7 0.06 13.5 0.1 2.1 1 1 1 2 2 2 0 Plasmodium falciparum UIS3 membrane protein DUF3588 PF12140.3 ETO35472.1 - 0.0059 16.6 0.3 0.027 14.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3588) DUF177 PF02620.12 ETO35472.1 - 2.4 8.2 5.8 0.65 10.0 0.1 2.7 3 0 0 3 3 3 0 Uncharacterized ACR, COG1399 Kelch_1 PF01344.20 ETO35473.1 - 7.5e-05 22.2 0.7 0.0016 17.9 0.3 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.1 ETO35473.1 - 0.00021 20.9 0.0 0.034 13.8 0.0 2.4 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO35473.1 - 0.0011 18.6 0.5 0.064 13.0 0.1 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETO35473.1 - 0.0028 17.7 1.6 0.021 15.0 0.2 2.6 1 1 1 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO35473.1 - 0.078 13.1 0.1 0.39 10.9 0.0 2.2 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO35473.1 - 0.16 11.9 0.8 4.1 7.4 0.2 2.4 2 0 0 2 2 2 0 Kelch motif DUF520 PF04461.8 ETO35474.1 - 0.087 12.6 0.4 0.11 12.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF520) GA PF01468.12 ETO35474.1 - 0.099 12.8 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 GA module Abhydrolase_3 PF07859.8 ETO35475.1 - 0.16 11.5 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold RRM_5 PF13893.1 ETO35476.1 - 1.8e-09 37.3 0.2 2.4e-09 36.8 0.2 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO35476.1 - 7.6e-08 31.8 0.0 1.3e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO35476.1 - 0.00023 21.0 0.0 0.00036 20.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FlxA PF14282.1 ETO35477.1 - 1.8 8.5 21.1 0.87 9.5 6.7 3.3 2 1 0 2 2 2 0 FlxA-like protein DUF3552 PF12072.3 ETO35477.1 - 5 6.2 9.4 0.4 9.8 3.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Tubulin PF00091.20 ETO35478.1 - 7.1e-12 45.6 0.1 1.1e-11 45.0 0.1 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETO35478.1 - 3.2e-05 23.9 0.0 5.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain DUF226 PF02890.9 ETO35478.1 - 0.1 12.3 7.1 0.17 11.6 4.9 1.3 1 0 0 1 1 1 0 Borrelia family of unknown function DUF226 PDZ PF00595.19 ETO35479.1 - 2.8e-06 27.3 0.0 5.2e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 ETO35479.1 - 4.9e-05 23.1 0.0 6.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 PDZ domain SusE PF14292.1 ETO35479.1 - 0.093 12.5 0.1 0.15 11.8 0.0 1.4 1 1 0 1 1 1 0 SusE outer membrane protein Pkinase PF00069.20 ETO35480.1 - 0.00058 19.0 3.2 0.0011 18.1 2.2 1.5 1 1 0 1 1 1 1 Protein kinase domain DUF2339 PF10101.4 ETO35481.1 - 0.25 9.5 12.2 0.82 7.8 1.5 2.5 2 1 1 3 3 3 0 Predicted membrane protein (DUF2339) FUSC PF04632.7 ETO35482.1 - 0.25 9.7 3.8 0.84 7.9 0.0 2.5 2 1 1 3 3 3 0 Fusaric acid resistance protein family ZYG-11_interact PF05884.7 ETO35482.1 - 6.8 5.6 13.3 25 3.8 3.5 3.8 3 1 1 4 4 4 0 Interactor of ZYG-11 Reo_sigmaC PF04582.7 ETO35483.1 - 0.00041 19.6 4.0 0.24 10.5 0.2 2.3 1 1 1 2 2 2 2 Reovirus sigma C capsid protein IncA PF04156.9 ETO35483.1 - 0.28 10.7 0.1 0.28 10.7 0.0 4.0 2 2 1 3 3 3 0 IncA protein Baculo_PEP_C PF04513.7 ETO35483.1 - 0.48 10.2 7.0 2.2 8.1 0.1 3.4 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus LSM PF01423.17 ETO35484.1 - 0.00018 21.0 0.9 0.00024 20.5 0.1 1.7 2 0 0 2 2 2 1 LSM domain UPF0697 PF15117.1 ETO35484.1 - 0.07 12.8 0.6 0.19 11.5 0.4 1.8 1 1 0 1 1 1 0 Uncharacterised protein family UPF0697 SAYSvFN PF10260.4 ETO35484.1 - 0.66 9.7 0.1 0.66 9.7 0.0 2.5 2 1 2 4 4 4 0 Uncharacterized conserved domain (SAYSvFN) Ras PF00071.17 ETO35486.1 - 7.8e-55 184.6 2.2 1.7e-35 121.7 0.1 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 ETO35486.1 - 1.2e-13 51.6 0.5 2.4e-12 47.3 0.1 2.4 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO35486.1 - 2.3e-11 43.2 0.6 1.1e-07 31.2 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO35486.1 - 8.9e-08 31.7 0.2 1.7e-07 30.8 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 ETO35486.1 - 0.00086 19.2 0.2 0.0016 18.3 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Hpr_kinase_C PF07475.7 ETO35486.1 - 0.011 15.0 0.3 2.4 7.4 0.0 2.7 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain DUF258 PF03193.11 ETO35486.1 - 0.014 14.5 0.0 0.033 13.3 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 ETO35486.1 - 0.016 15.3 0.1 0.039 14.1 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 ETO35486.1 - 0.038 13.5 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 ETO35486.1 - 0.04 13.9 0.1 0.095 12.6 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain Gtr1_RagA PF04670.7 ETO35486.1 - 0.06 12.4 0.6 0.98 8.5 0.4 2.2 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region cobW PF02492.14 ETO35486.1 - 0.08 12.3 0.2 2 7.8 0.0 2.4 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.13 ETO35486.1 - 0.11 11.7 0.0 8.6 5.6 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B ABC_tran PF00005.22 ETO35486.1 - 0.13 12.6 1.3 0.25 11.6 0.9 1.9 1 1 0 1 1 1 0 ABC transporter DUF4199 PF13858.1 ETO35487.1 - 0.0021 18.0 1.9 0.0025 17.7 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4199) PXT1 PF15214.1 ETO35487.1 - 2.8 8.2 5.3 11 6.4 0.1 3.0 2 1 0 2 2 2 0 Peroxisomal testis-specific protein 1 ACR_tran PF00873.14 ETO35488.1 - 0.5 7.6 1.8 0.79 7.0 1.2 1.3 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Pilt PF15453.1 ETO35488.1 - 3.3 7.2 14.7 4.4 6.9 10.2 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions IL15 PF02372.10 ETO35488.1 - 3.8 7.2 8.6 0.63 9.8 1.4 2.3 1 1 1 2 2 2 0 Interleukin 15 TraF PF13728.1 ETO35490.1 - 0.00031 20.3 0.4 0.00044 19.8 0.3 1.4 1 0 0 1 1 1 1 F plasmid transfer operon protein DUF3740 PF12548.3 ETO35490.1 - 0.0072 16.6 4.0 0.0072 16.6 2.8 2.7 1 1 2 3 3 3 1 Sulfatase protein PA26 PF04636.8 ETO35490.1 - 0.014 14.1 4.8 0.018 13.7 3.3 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Zip PF02535.17 ETO35490.1 - 0.21 10.5 1.8 0.33 9.9 1.2 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Ndc1_Nup PF09531.5 ETO35490.1 - 0.32 9.3 6.4 0.37 9.1 4.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF106 PF01956.11 ETO35490.1 - 0.41 10.1 8.2 0.082 12.4 0.4 2.3 2 0 0 2 2 2 0 Integral membrane protein DUF106 SOBP PF15279.1 ETO35490.1 - 3.1 8.0 11.9 4.4 7.5 8.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein UPF0560 PF10577.4 ETO35490.1 - 5 5.2 10.7 6.6 4.8 7.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 SelP_N PF04592.9 ETO35491.1 - 0.11 11.9 6.8 0.12 11.7 4.7 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region NPR3 PF03666.8 ETO35491.1 - 0.24 9.8 9.0 0.27 9.7 6.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Neur_chan_memb PF02932.11 ETO35491.1 - 0.57 10.0 4.7 0.64 9.8 3.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Transformer PF06495.6 ETO35491.1 - 0.71 9.7 9.9 0.87 9.4 6.9 1.1 1 0 0 1 1 1 0 Fruit fly transformer protein DUF3827 PF12877.2 ETO35491.1 - 6.3 4.7 12.4 7.4 4.5 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF2413 PF10310.4 ETO35491.1 - 8.5 5.0 15.9 13 4.4 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) TB2_DP1_HVA22 PF03134.14 ETO35492.1 - 0.069 12.9 6.8 0.065 12.9 1.5 2.2 2 0 0 2 2 2 0 TB2/DP1, HVA22 family AAA_5 PF07728.9 ETO35493.1 - 0.0027 17.4 0.3 0.015 15.0 0.0 2.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA PF00004.24 ETO35493.1 - 0.084 13.0 0.0 0.54 10.4 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Tubulin PF00091.20 ETO35494.1 - 2.2e-51 174.7 0.1 2.9e-51 174.3 0.1 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Lipase_3 PF01764.20 ETO35494.1 - 0.011 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Pkinase PF00069.20 ETO35497.1 - 2.5e-22 79.2 0.2 3e-22 79.0 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO35497.1 - 2.2e-11 43.3 0.1 2.5e-11 43.1 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase SprT-like PF10263.4 ETO35499.1 - 0.0088 15.7 0.1 0.0088 15.7 0.0 2.2 3 0 0 3 3 3 1 SprT-like family BPL_LplA_LipB PF03099.14 ETO35500.1 - 1.1e-09 38.3 0.0 2.8e-09 37.0 0.0 1.7 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family OTCace PF00185.19 ETO35501.1 - 6.9e-39 133.2 0.1 2.5e-38 131.4 0.0 1.9 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain AA_kinase PF00696.23 ETO35501.1 - 5.4e-28 98.1 0.2 7.5e-28 97.6 0.1 1.2 1 0 0 1 1 1 1 Amino acid kinase family EamA PF00892.15 ETO35502.1 - 0.003 17.5 9.7 0.003 17.5 6.7 3.6 5 0 0 5 5 5 2 EamA-like transporter family DUF1218 PF06749.7 ETO35504.1 - 0.063 13.7 0.3 0.093 13.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1218) VWC PF00093.13 ETO35505.1 - 3.8 7.6 12.0 0.12 12.4 3.2 2.2 2 1 0 2 2 2 0 von Willebrand factor type C domain zf-HC5HC2H_2 PF13832.1 ETO35507.1 - 1.3e-12 47.6 19.0 3.2e-08 33.5 7.7 3.7 2 1 0 2 2 2 2 PHD-zinc-finger like domain PHD_2 PF13831.1 ETO35507.1 - 3.6e-10 38.9 2.3 3.6e-10 38.9 1.6 2.5 3 0 0 3 3 3 1 PHD-finger zf-HC5HC2H PF13771.1 ETO35507.1 - 1.1e-07 31.9 22.2 1.4e-05 25.1 5.0 4.1 2 2 1 3 3 3 2 PHD-like zinc-binding domain PHD PF00628.24 ETO35507.1 - 1.4e-05 24.6 6.2 1.4e-05 24.6 4.3 3.4 4 0 0 4 4 4 2 PHD-finger C1_1 PF00130.17 ETO35507.1 - 0.02 14.6 2.9 0.02 14.6 2.0 3.7 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TIM PF00121.13 ETO35508.1 - 7.5e-79 264.2 1.5 2.3e-78 262.6 1.0 1.6 1 1 0 1 1 1 1 Triosephosphate isomerase PUF PF00806.14 ETO35509.1 - 3.9e-24 82.7 5.3 8.5e-05 21.8 0.0 6.6 6 0 0 6 6 6 6 Pumilio-family RNA binding repeat FAM86 PF14904.1 ETO35509.1 - 0.78 9.5 3.6 12 5.6 0.0 3.6 4 0 0 4 4 4 0 Family of unknown function IF4E PF01652.13 ETO35510.1 - 0.00042 19.8 2.6 0.0012 18.3 1.8 1.8 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E RGS PF00615.14 ETO35510.1 - 0.047 13.7 2.1 0.084 12.9 0.2 2.3 2 0 0 2 2 2 0 Regulator of G protein signaling domain CPSF100_C PF13299.1 ETO35511.1 - 1.2 9.3 7.9 13 5.9 0.7 3.3 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal F420_oxidored PF03807.12 ETO35512.1 - 5e-20 71.7 0.5 1.3e-19 70.4 0.3 1.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 ETO35512.1 - 4.9e-08 32.8 0.0 6e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 ETO35512.1 - 5.7e-07 29.5 0.1 9e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 ETO35512.1 - 2e-05 24.0 0.1 2.8e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA IlvN PF07991.7 ETO35512.1 - 0.00014 21.3 0.4 0.0014 18.0 0.3 2.0 1 1 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain UDPG_MGDP_dh_N PF03721.9 ETO35512.1 - 0.00015 21.2 0.3 0.00051 19.4 0.2 1.8 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_10 PF13460.1 ETO35512.1 - 0.00016 21.7 0.9 0.00053 20.0 0.6 1.7 1 1 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 ETO35512.1 - 0.00033 20.3 0.3 0.00053 19.6 0.2 1.3 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 ETO35512.1 - 0.00042 19.5 0.3 0.0015 17.7 0.2 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rossmann-like PF10727.4 ETO35512.1 - 0.00043 20.0 0.7 0.035 13.8 0.5 2.1 1 1 0 1 1 1 1 Rossmann-like domain NAD_binding_7 PF13241.1 ETO35512.1 - 0.00085 19.5 0.1 0.0012 19.0 0.0 1.1 1 0 0 1 1 1 1 Putative NAD(P)-binding PDH PF02153.12 ETO35512.1 - 0.0017 17.3 0.2 0.016 14.1 0.1 1.9 1 1 1 2 2 2 1 Prephenate dehydrogenase Semialdhyde_dh PF01118.19 ETO35512.1 - 0.0032 17.7 0.2 0.0055 17.0 0.2 1.4 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 ETO35512.1 - 0.0085 15.3 0.2 0.012 14.8 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family UDPG_MGDP_dh_C PF03720.10 ETO35512.1 - 0.012 15.7 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain DUF2338 PF10100.4 ETO35512.1 - 0.028 12.8 0.0 0.033 12.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2338) TrkA_N PF02254.13 ETO35512.1 - 0.03 14.3 0.3 0.19 11.7 0.2 2.0 1 1 0 1 1 1 0 TrkA-N domain SAICAR_synt PF01259.13 ETO35513.1 - 0.044 12.8 0.0 0.063 12.3 0.0 1.3 1 1 0 1 1 1 0 SAICAR synthetase Lambda_Kil PF06301.6 ETO35513.1 - 0.16 11.4 0.7 17 4.9 0.1 2.4 2 0 0 2 2 2 0 Bacteriophage lambda Kil protein adh_short PF00106.20 ETO35514.1 - 2.5e-19 69.8 0.0 1e-18 67.8 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETO35514.1 - 9.2e-11 41.7 0.0 4e-10 39.6 0.0 1.9 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 ETO35514.1 - 5.7e-05 23.0 0.1 0.00022 21.0 0.0 2.0 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETO35514.1 - 0.0026 17.2 0.0 0.0064 15.9 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETO35514.1 - 0.026 14.5 0.0 0.061 13.3 0.0 1.6 1 0 0 1 1 1 0 NADH(P)-binding CW_binding_2 PF04122.7 ETO35514.1 - 0.028 14.6 0.1 0.079 13.1 0.1 1.7 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 Ded_cyto PF06920.8 ETO35514.1 - 0.071 12.4 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Dedicator of cytokinesis DUF1283 PF06932.6 ETO35514.1 - 0.43 10.6 4.0 0.49 10.4 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1283) Nrap PF03813.9 ETO35515.1 - 6.6e-30 103.4 6.5 2.3e-20 71.8 0.3 3.1 3 1 0 3 3 3 2 Nrap protein DUF3446 PF11928.3 ETO35515.1 - 0.22 11.7 21.3 0.14 12.3 1.5 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) NusA_N PF08529.6 ETO35518.1 - 0.075 13.0 1.2 0.12 12.4 0.8 1.3 1 0 0 1 1 1 0 NusA N-terminal domain Paramyx_P_V_C PF03210.8 ETO35519.1 - 0.11 12.3 8.5 0.22 11.3 0.3 2.9 3 0 0 3 3 3 0 Paramyxovirus P/V phosphoprotein C-terminal Peptidase_A8 PF01252.13 ETO35520.1 - 0.13 11.8 1.3 0.87 9.1 0.2 2.2 2 0 0 2 2 2 0 Signal peptidase (SPase) II DUF498 PF04430.9 ETO35520.1 - 0.13 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) p450 PF00067.17 ETO35521.1 - 2.9e-54 184.3 2.3 2.1e-53 181.4 0.3 2.0 2 0 0 2 2 2 2 Cytochrome P450 G-alpha PF00503.15 ETO35522.1 - 9e-77 258.3 6.4 1.3e-69 234.7 1.8 2.0 2 0 0 2 2 2 2 G-protein alpha subunit Arf PF00025.16 ETO35522.1 - 2.3e-08 33.4 0.3 0.00014 21.1 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 ETO35522.1 - 0.0014 19.1 0.2 0.59 10.6 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 ETO35522.1 - 0.035 13.6 0.4 0.035 13.6 0.3 2.3 3 1 0 3 3 3 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 ETO35522.1 - 0.035 14.0 0.0 6.1 6.8 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.22 ETO35522.1 - 0.16 12.2 0.4 0.48 10.7 0.3 1.7 1 1 0 1 1 1 0 ABC transporter Gtr1_RagA PF04670.7 ETO35522.1 - 0.41 9.7 3.5 12 4.9 0.0 2.5 1 1 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_21 PF13304.1 ETO35522.1 - 0.57 10.0 2.7 6.1 6.7 1.8 2.1 1 1 0 1 1 1 0 AAA domain Sulfotransfer_1 PF00685.22 ETO35524.1 - 0.0011 18.3 3.2 0.0031 16.8 2.2 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 ETO35524.1 - 0.0073 17.2 0.2 0.013 16.3 0.1 1.5 1 1 0 1 1 1 1 Sulfotransferase family Sdh5 PF03937.11 ETO35524.1 - 0.1 12.2 1.5 0.2 11.3 1.0 1.5 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase RNA_pol_I_A49 PF06870.7 ETO35525.1 - 0.00011 20.9 0.0 0.00027 19.6 0.0 1.5 1 1 0 1 1 1 1 A49-like RNA polymerase I associated factor zf-LSD1 PF06943.7 ETO35525.1 - 0.029 13.9 0.4 0.054 13.1 0.3 1.4 1 0 0 1 1 1 0 LSD1 zinc finger RGS PF00615.14 ETO35526.1 - 5.1e-05 23.3 1.5 8.7e-05 22.6 0.1 2.1 2 0 0 2 2 2 1 Regulator of G protein signaling domain Protoglobin PF11563.3 ETO35526.1 - 0.018 14.7 0.1 0.037 13.6 0.1 1.5 1 0 0 1 1 1 0 Protoglobin RhoGAP PF00620.22 ETO35527.1 - 9.8e-12 44.7 0.0 1.3e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain PBD PF00786.23 ETO35527.1 - 0.051 13.9 0.0 0.14 12.5 0.0 1.9 1 0 0 1 1 1 0 P21-Rho-binding domain Utp13 PF08625.6 ETO35528.1 - 0.1 12.2 3.3 0.09 12.4 1.5 1.5 1 1 0 1 1 1 0 Utp13 specific WD40 associated domain DUF1477 PF07346.6 ETO35528.1 - 0.12 12.4 4.7 0.25 11.4 3.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1477) PEX11 PF05648.9 ETO35528.1 - 0.14 11.3 3.6 0.12 11.6 1.9 1.3 1 1 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) TPX2 PF06886.6 ETO35528.1 - 0.75 9.9 9.4 0.19 11.7 3.3 2.2 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) SCFA_trans PF02667.9 ETO35528.1 - 0.76 8.4 5.2 0.71 8.5 2.8 1.5 1 1 1 2 2 2 0 Short chain fatty acid transporter Bap31 PF05529.7 ETO35528.1 - 1.4 8.2 11.5 4.2 6.7 8.0 1.8 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like Tn7_Tnp_TnsA_N PF08722.6 ETO35528.1 - 1.6 8.7 5.1 2.4 8.1 2.9 1.9 1 1 0 1 1 1 0 TnsA endonuclease N terminal DUF3139 PF11337.3 ETO35528.1 - 2.1 8.7 8.4 1.8 8.8 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3139) DUF4355 PF14265.1 ETO35530.1 - 0.31 11.0 19.0 0.35 10.8 13.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Bap31 PF05529.7 ETO35530.1 - 1.9 7.9 5.5 2.1 7.7 3.8 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like NPR3 PF03666.8 ETO35530.1 - 3 6.2 7.9 2.9 6.3 5.5 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Exo_endo_phos_2 PF14529.1 ETO35534.1 - 2e-08 33.8 1.2 9.4e-08 31.6 0.1 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 ETO35534.1 - 0.015 15.6 0.0 0.038 14.3 0.0 1.6 2 0 0 2 2 2 0 RNase H Toxin_46 PF15526.1 ETO35535.1 - 0.31 11.2 1.8 0.5 10.5 0.3 1.9 2 0 0 2 2 2 0 Putative toxin 46 DUF4206 PF13901.1 ETO35536.1 - 2.2e-09 37.1 7.1 1.3e-08 34.6 2.1 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4206) zf-RING_2 PF13639.1 ETO35536.1 - 0.15 11.9 2.2 0.53 10.1 1.6 2.0 1 0 0 1 1 1 0 Ring finger domain PARP PF00644.15 ETO35537.1 - 2.5e-12 46.6 0.2 2.5e-12 46.6 0.1 2.4 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain NAD_binding_8 PF13450.1 ETO35538.1 - 4.1e-12 45.9 1.1 6.6e-12 45.2 0.7 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ETO35538.1 - 4.5e-09 35.6 0.2 5.7e-09 35.3 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETO35538.1 - 1.1e-06 27.8 0.3 1.3e-06 27.5 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 ETO35538.1 - 1.5e-06 27.5 0.2 2.1e-06 27.0 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 ETO35538.1 - 5.8e-06 25.6 0.1 7.2e-06 25.3 0.1 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 ETO35538.1 - 2.1e-05 24.5 0.8 2.7e-05 24.1 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETO35538.1 - 2.8e-05 23.3 0.1 3.3e-05 23.0 0.1 1.1 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 ETO35538.1 - 9.8e-05 20.9 0.1 0.00013 20.5 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 ETO35538.1 - 0.00022 21.5 0.1 0.00044 20.5 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 ETO35538.1 - 0.001 17.4 0.0 0.0016 16.8 0.0 1.3 1 0 0 1 1 1 1 GDP dissociation inhibitor GIDA PF01134.17 ETO35538.1 - 0.0014 17.5 0.2 0.002 17.0 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 ETO35538.1 - 0.0014 17.7 0.2 0.002 17.2 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 ETO35538.1 - 0.0056 16.7 0.1 0.0085 16.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETO35538.1 - 0.03 13.2 0.1 0.041 12.7 0.1 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein DOT1 PF08123.8 ETO35538.1 - 0.13 11.5 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Strep_67kDa_ant PF06100.6 ETO35538.1 - 0.23 9.7 2.0 0.56 8.4 0.2 1.9 1 1 1 2 2 2 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Pkinase PF00069.20 ETO35540.1 - 1.5e-51 175.0 0.1 1.9e-51 174.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO35540.1 - 8e-22 77.5 0.0 9.5e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETO35540.1 - 0.00023 20.2 0.0 0.00047 19.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETO35540.1 - 0.001 18.1 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETO35540.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family PRT_C PF08372.5 ETO35541.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal Peptidase_S64 PF08192.6 ETO35541.1 - 0.62 8.3 5.6 1.6 6.9 2.3 1.9 2 0 0 2 2 2 0 Peptidase family S64 ATP-synt_DE_N PF02823.11 ETO35542.1 - 4.3e-14 52.0 0.0 6e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ATP-synt_DE PF00401.15 ETO35542.1 - 0.042 13.7 0.7 0.081 12.8 0.5 1.5 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Peptidase_C54 PF03416.14 ETO35543.1 - 1.6e-29 102.8 4.6 8.4e-29 100.5 3.2 2.0 1 1 0 1 1 1 1 Peptidase family C54 CDC45 PF02724.9 ETO35543.1 - 0.001 17.1 31.6 0.02 12.9 9.9 2.1 2 0 0 2 2 2 2 CDC45-like protein SDA1 PF05285.7 ETO35543.1 - 0.0026 17.1 26.4 0.018 14.3 3.9 2.3 2 0 0 2 2 2 2 SDA1 MIP-T3 PF10243.4 ETO35543.1 - 0.0036 15.8 24.6 0.0068 14.9 17.1 1.4 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 TIMELESS PF04821.9 ETO35543.1 - 0.013 14.7 2.0 0.013 14.7 1.4 2.1 2 0 0 2 2 2 0 Timeless protein Daxx PF03344.10 ETO35543.1 - 0.19 10.1 32.8 0.84 8.0 9.7 2.2 2 0 0 2 2 2 0 Daxx Family Nucleoplasmin PF03066.10 ETO35543.1 - 0.35 10.3 20.4 1.8 8.0 4.7 2.6 2 0 0 2 2 2 0 Nucleoplasmin Rtf2 PF04641.7 ETO35543.1 - 0.95 8.6 21.7 0.72 8.9 6.7 2.4 2 0 0 2 2 2 0 Rtf2 RING-finger CobT PF06213.7 ETO35543.1 - 1.4 7.9 35.8 0.67 9.0 10.5 2.3 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT U79_P34 PF03064.11 ETO35543.1 - 7.6 5.9 29.5 6.2 6.2 4.5 2.5 2 0 0 2 2 2 0 HSV U79 / HCMV P34 Sgf11 PF08209.6 ETO35544.1 - 3.2e-05 23.1 29.9 0.26 10.6 0.2 6.6 7 0 0 7 7 7 4 Sgf11 (transcriptional regulation protein) DZR PF12773.2 ETO35544.1 - 0.0093 15.7 29.2 3.7 7.4 3.5 6.2 1 1 4 5 5 5 1 Double zinc ribbon zf-Di19 PF05605.7 ETO35544.1 - 0.017 15.2 8.7 53 4.0 0.0 5.5 5 1 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding DUF329 PF03884.9 ETO35544.1 - 0.034 13.6 13.1 36 4.0 0.1 5.6 5 0 0 5 5 5 0 Domain of unknown function (DUF329) DUF3797 PF12677.2 ETO35544.1 - 0.043 13.4 24.4 4.5 6.9 0.1 5.8 5 1 0 5 5 5 0 Domain of unknown function (DUF3797) DUF730 PF05325.6 ETO35544.1 - 0.045 13.5 8.4 17 5.2 0.0 4.7 4 1 0 4 4 4 0 Protein of unknown function (DUF730) GFA PF04828.9 ETO35544.1 - 0.13 12.1 27.6 3.3 7.7 0.7 5.5 1 1 4 5 5 5 0 Glutathione-dependent formaldehyde-activating enzyme Mut7-C PF01927.11 ETO35544.1 - 0.33 10.9 30.4 0.56 10.1 0.1 5.9 1 1 4 5 5 5 0 Mut7-C RNAse domain Ribosomal_L37ae PF01780.14 ETO35544.1 - 0.78 9.6 33.4 3.4 7.6 1.6 5.2 2 2 2 5 5 5 0 Ribosomal L37ae protein family DUF164 PF02591.10 ETO35544.1 - 0.94 9.3 16.3 12 5.8 0.0 6.6 6 1 2 8 8 8 0 Putative zinc ribbon domain zf-H2C2_2 PF13465.1 ETO35544.1 - 1.1 9.6 37.4 1.9 8.9 0.3 6.7 6 0 0 6 6 6 0 Zinc-finger double domain CpXC PF14353.1 ETO35544.1 - 1.2 9.0 18.3 5.8 6.8 0.2 5.6 4 2 1 6 6 6 0 CpXC protein Zn_Tnp_IS91 PF14319.1 ETO35544.1 - 2 7.9 29.9 0.82 9.2 1.1 5.0 1 1 2 5 5 5 0 Transposase zinc-binding domain Med12-LCEWAV PF12145.3 ETO35544.1 - 2.2 6.6 6.9 5 5.4 0.1 2.9 1 1 4 5 5 5 0 Eukaryotic Mediator 12 subunit domain Ribosomal_S27e PF01667.12 ETO35544.1 - 2.7 7.5 21.1 5 6.7 0.6 5.2 5 0 0 5 5 5 0 Ribosomal protein S27 Acetone_carb_G PF08882.6 ETO35544.1 - 2.8 7.9 6.0 3 7.8 0.2 3.6 5 0 0 5 5 5 0 Acetone carboxylase gamma subunit PilX PF13681.1 ETO35544.1 - 3.2 8.3 20.6 0.58 10.6 1.0 4.3 1 1 2 4 4 4 0 Type IV pilus assembly protein PilX C-term Sgf11 PF08209.6 ETO35545.1 - 0.021 14.1 0.1 0.037 13.3 0.1 1.4 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) zinc_ribbon_2 PF13240.1 ETO35545.1 - 0.086 12.3 0.3 0.94 9.0 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain TPR_12 PF13424.1 ETO35546.1 - 5e-32 109.6 3.5 4.1e-13 49.0 0.0 2.8 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO35546.1 - 3.8e-14 51.6 6.0 6.4e-06 25.5 0.1 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO35546.1 - 1.2e-13 50.4 1.4 2.9e-08 33.2 0.1 2.9 2 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 ETO35546.1 - 2.7e-09 36.2 1.9 0.012 15.4 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO35546.1 - 1.1e-08 34.1 0.3 0.021 14.5 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO35546.1 - 5.1e-08 32.1 11.7 0.0038 16.8 0.1 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO35546.1 - 1.4e-05 24.8 0.0 0.082 12.8 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 ETO35546.1 - 2.6e-05 24.0 2.6 0.74 9.7 0.3 3.8 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_14 PF13428.1 ETO35546.1 - 0.017 15.7 0.0 18 6.3 0.0 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO35546.1 - 0.065 13.7 1.3 2.9 8.5 0.1 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_3 PF07720.7 ETO35546.1 - 0.61 9.9 7.8 5.2 6.9 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat FimP PF09766.4 ETO35547.1 - 0.01 14.9 6.0 0.014 14.5 4.2 1.2 1 0 0 1 1 1 0 Fms-interacting protein DHHW PF14286.1 ETO35547.1 - 0.013 14.8 2.6 0.017 14.4 1.8 1.0 1 0 0 1 1 1 0 DHHW protein Tom37_C PF11801.3 ETO35547.1 - 0.016 15.0 2.7 0.02 14.7 1.9 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain VID27 PF08553.5 ETO35547.1 - 0.017 13.4 10.0 0.02 13.1 6.9 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein TLP-20 PF06088.6 ETO35547.1 - 0.018 14.6 5.1 0.021 14.4 3.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) NOA36 PF06524.7 ETO35547.1 - 0.068 12.4 7.7 0.086 12.0 5.3 1.0 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 ETO35547.1 - 0.28 9.1 11.1 0.36 8.8 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid PF03115.9 ETO35547.1 - 0.34 9.1 3.7 0.37 8.9 2.6 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF912 PF06024.7 ETO35547.1 - 0.43 10.6 5.7 0.66 10.0 3.9 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) RRN3 PF05327.6 ETO35547.1 - 1.9 6.5 8.5 2.4 6.1 5.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FAM176 PF14851.1 ETO35547.1 - 4.9 6.8 6.7 7.3 6.2 4.6 1.3 1 0 0 1 1 1 0 FAM176 family FYDLN_acid PF09538.5 ETO35547.1 - 4.9 7.7 16.4 18 5.9 11.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Actin PF00022.14 ETO35548.1 - 2.8e-16 58.9 0.0 3e-16 58.8 0.0 1.0 1 0 0 1 1 1 1 Actin WD40 PF00400.27 ETO35549.1 - 7.9e-54 177.7 25.7 7.8e-12 44.6 0.0 7.1 6 1 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO35549.1 - 1.3e-07 30.1 5.9 0.0094 14.1 0.1 4.6 2 2 1 3 3 3 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO35549.1 - 0.0074 16.0 2.4 7.4 6.3 0.2 4.6 4 2 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region HAD PF12710.2 ETO35549.1 - 0.12 12.4 0.3 28 4.7 0.1 3.1 2 2 0 2 2 2 0 haloacid dehalogenase-like hydrolase OMP_b-brl_2 PF13568.1 ETO35550.1 - 0.07 12.9 0.7 0.12 12.1 0.2 1.5 1 1 1 2 2 2 0 Outer membrane protein beta-barrel domain Methyltransf_25 PF13649.1 ETO35551.1 - 2.6e-05 24.4 0.0 0.00015 22.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO35551.1 - 0.00053 19.6 1.4 0.02 14.4 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETO35551.1 - 0.00063 19.4 0.0 0.00097 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO35551.1 - 0.0011 19.4 0.0 0.002 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 ETO35551.1 - 0.0046 16.6 0.5 0.017 14.8 0.1 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO35551.1 - 0.0047 17.3 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETO35551.1 - 0.018 14.1 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 ETO35551.1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TBPIP_N PF15517.1 ETO35551.1 - 0.21 11.2 1.0 0.43 10.2 0.1 1.9 2 0 0 2 2 2 0 TBP-interacting protein N-terminus SAM_1 PF00536.25 ETO35552.1 - 3.4e-11 43.1 4.2 3.6e-08 33.4 0.2 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO35552.1 - 1.4e-10 40.8 1.7 7.9e-08 32.0 0.2 2.9 3 0 0 3 3 3 2 SAM domain (Sterile alpha motif) TPR_11 PF13414.1 ETO35553.1 - 1.6e-06 27.6 0.3 0.014 15.0 0.1 2.2 2 0 0 2 2 2 2 TPR repeat Apc3 PF12895.2 ETO35553.1 - 4.1e-05 23.6 0.6 0.036 14.1 0.0 2.3 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 ETO35553.1 - 0.00016 21.3 1.3 0.019 14.8 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO35553.1 - 0.00069 20.0 0.0 0.67 10.7 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO35553.1 - 0.0013 18.6 0.2 0.0037 17.1 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO35553.1 - 0.0019 17.8 0.0 0.1 12.4 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO35553.1 - 0.0089 16.3 0.1 1.2 9.4 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO35553.1 - 0.01 15.7 0.4 0.24 11.3 0.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 ETO35553.1 - 0.025 14.7 0.3 0.094 12.9 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETO35553.1 - 0.16 11.6 2.7 0.21 11.2 0.1 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat RNase_H2-Ydr279 PF09468.5 ETO35553.1 - 0.3 10.2 5.7 0.39 9.8 4.0 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Kinesin PF00225.18 ETO35554.1 - 2.1e-48 164.7 11.1 1.8e-25 89.3 0.3 2.5 3 0 0 3 3 3 2 Kinesin motor domain Calcyon PF06387.6 ETO35556.1 - 0.55 9.5 4.5 0.66 9.3 0.8 2.6 3 0 0 3 3 3 0 D1 dopamine receptor-interacting protein (calcyon) UPF0560 PF10577.4 ETO35556.1 - 1.8 6.7 5.1 2.6 6.2 3.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 CDC45 PF02724.9 ETO35556.1 - 3.8 5.4 11.4 5.7 4.8 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein LRR_8 PF13855.1 ETO35557.1 - 1.4e-09 37.5 23.6 9.2e-07 28.5 5.3 3.7 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 ETO35557.1 - 1.6e-09 37.1 15.1 1.5e-06 27.6 1.2 3.9 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) MUG113 PF13455.1 ETO35557.1 - 0.099 13.1 1.2 0.34 11.3 0.3 2.1 2 0 0 2 2 2 0 Meiotically up-regulated gene 113 V-SNARE PF05008.10 ETO35558.1 - 0.0041 17.2 1.0 0.0094 16.0 0.7 1.6 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus DUF2489 PF10675.4 ETO35558.1 - 0.012 15.3 0.2 0.029 14.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) V_ATPase_I PF01496.14 ETO35558.1 - 0.02 12.7 1.7 0.026 12.3 1.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TBPIP PF07106.8 ETO35558.1 - 0.72 9.3 8.7 0.35 10.3 1.2 2.5 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PFEMP PF03011.10 ETO35558.1 - 1.2 9.4 5.1 1 9.6 1.9 1.8 1 1 1 2 2 2 0 PFEMP DBL domain RRM_6 PF14259.1 ETO35559.1 - 5.3e-06 26.3 0.1 0.0068 16.3 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO35559.1 - 0.00038 20.2 0.3 0.014 15.2 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LAGLIDADG_1 PF00961.14 ETO35560.1 - 0.058 13.9 3.8 0.064 13.8 1.8 1.6 1 1 0 1 1 1 0 LAGLIDADG endonuclease Rtf2 PF04641.7 ETO35561.1 - 0.0023 17.2 6.9 0.003 16.7 4.8 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger MRI PF15325.1 ETO35561.1 - 0.74 10.8 6.6 0.8 10.6 4.0 1.5 1 1 0 1 1 1 0 Modulator of retrovirus infection WD40 PF00400.27 ETO35563.1 - 1.6e-81 265.5 23.1 8.7e-13 47.6 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO35563.1 - 1.1e-08 33.7 7.7 0.43 8.6 0.0 5.7 1 1 5 6 6 6 4 Nucleoporin Nup120/160 PD40 PF07676.7 ETO35563.1 - 7.9e-08 31.8 8.3 0.59 9.8 0.0 6.3 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO35563.1 - 1.5e-06 26.7 0.8 0.00076 17.8 0.0 3.0 1 1 2 3 3 3 2 Cytochrome D1 heme domain DPPIV_N PF00930.16 ETO35563.1 - 3e-05 22.7 0.1 0.037 12.6 0.0 3.3 1 1 2 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region PQQ_2 PF13360.1 ETO35563.1 - 4.9e-05 22.8 2.5 0.00057 19.4 1.6 2.8 1 1 1 2 2 2 1 PQQ-like domain Nucleoporin_N PF08801.6 ETO35563.1 - 0.00063 18.5 13.8 4.6 5.8 0.2 5.5 1 1 2 4 4 4 1 Nup133 N terminal like Proteasome_A_N PF10584.4 ETO35563.1 - 0.0063 15.8 4.9 13 5.1 0.0 5.2 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Nbas_N PF15492.1 ETO35563.1 - 0.008 15.3 2.1 3.1 6.8 0.1 3.5 1 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Hira PF07569.6 ETO35563.1 - 0.0098 15.1 0.1 3.7 6.7 0.0 3.8 2 2 0 3 3 3 1 TUP1-like enhancer of split Resistin PF06954.6 ETO35563.1 - 0.034 14.4 0.3 35 4.7 0.0 4.3 2 2 2 4 4 4 0 Resistin Mid2 PF04478.7 ETO35563.1 - 0.071 12.5 5.0 25 4.2 0.0 4.6 4 1 1 5 5 5 0 Mid2 like cell wall stress sensor CoA_trans PF01144.18 ETO35564.1 - 6.3e-37 126.8 0.0 8.4e-37 126.4 0.0 1.1 1 0 0 1 1 1 1 Coenzyme A transferase 7TMR-DISM_7TM PF07695.6 ETO35564.1 - 0.0058 16.3 0.3 0.0095 15.6 0.2 1.2 1 0 0 1 1 1 1 7TM diverse intracellular signalling AcetylCoA_hyd_C PF13336.1 ETO35564.1 - 0.012 15.3 0.1 0.02 14.5 0.1 1.3 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain CoA_trans PF01144.18 ETO35565.1 - 5.3e-52 176.1 0.3 3e-51 173.6 0.2 1.9 1 1 0 1 1 1 1 Coenzyme A transferase mRNA_cap_C PF03919.10 ETO35567.1 - 0.073 13.3 1.8 0.66 10.3 0.1 2.4 1 1 0 2 2 2 0 mRNA capping enzyme, C-terminal domain zf-CCHC PF00098.18 ETO35568.1 - 0.18 11.7 0.1 0.18 11.7 0.1 2.6 2 0 0 2 2 2 0 Zinc knuckle Zn_ribbon_recom PF13408.1 ETO35568.1 - 0.47 10.7 6.4 0.15 12.3 1.5 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain PPR_2 PF13041.1 ETO35571.1 - 0.0028 17.5 0.4 1.3 9.0 0.0 3.3 4 0 0 4 4 4 2 PPR repeat family PPR PF01535.15 ETO35571.1 - 0.0082 16.0 0.3 19 5.5 0.0 3.8 4 0 0 4 4 4 1 PPR repeat PPR_3 PF13812.1 ETO35571.1 - 0.013 15.7 1.5 22 5.6 0.0 4.0 4 0 0 4 4 4 0 Pentatricopeptide repeat domain SHNi-TPR PF10516.4 ETO35571.1 - 0.047 12.9 0.5 0.17 11.1 0.1 2.1 2 0 0 2 2 2 0 SHNi-TPR PPR_1 PF12854.2 ETO35571.1 - 0.25 10.8 7.7 21 4.6 0.1 4.6 5 0 0 5 5 5 0 PPR repeat PPR_2 PF13041.1 ETO35572.1 - 5.9e-06 26.1 0.1 0.16 11.9 0.0 2.9 2 1 1 3 3 3 2 PPR repeat family PPR PF01535.15 ETO35572.1 - 0.0044 16.9 3.7 0.58 10.2 0.0 3.5 4 0 0 4 4 4 2 PPR repeat Abhydrolase_3 PF07859.8 ETO35573.1 - 7.2e-19 68.2 0.0 4.7e-18 65.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 ETO35573.1 - 4e-08 32.2 4.1 8.6e-08 31.2 0.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 ETO35573.1 - 0.028 14.1 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3089 PF11288.3 ETO35573.1 - 0.095 11.8 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Beach PF02138.13 ETO35574.1 - 7.7e-53 179.6 3.7 1e-50 172.7 0.1 2.4 2 0 0 2 2 2 2 Beige/BEACH domain WD40 PF00400.27 ETO35574.1 - 1.7e-15 56.2 14.6 2.7e-09 36.5 0.3 5.4 5 1 0 5 5 5 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO35574.1 - 7.5e-05 21.6 1.1 0.00083 18.2 0.8 2.2 1 1 0 1 1 1 1 Nup133 N terminal like FTCD_C PF04961.7 ETO35575.1 - 0.017 14.5 0.1 0.029 13.7 0.1 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Nop14 PF04147.7 ETO35576.1 - 9.7e-06 23.8 10.8 1.3e-05 23.3 7.5 1.2 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 ETO35576.1 - 0.0014 16.8 9.9 0.0019 16.3 6.8 1.1 1 0 0 1 1 1 1 CDC45-like protein TRAP_alpha PF03896.11 ETO35576.1 - 0.02 13.8 5.9 0.033 13.1 4.1 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sigma70_ner PF04546.8 ETO35576.1 - 0.17 11.5 10.3 0.32 10.5 7.1 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Daxx PF03344.10 ETO35576.1 - 0.27 9.6 15.1 0.35 9.2 10.5 1.2 1 0 0 1 1 1 0 Daxx Family CobT PF06213.7 ETO35576.1 - 0.34 9.9 11.7 0.51 9.4 8.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4637 PF15470.1 ETO35576.1 - 1.2 8.7 6.4 2.5 7.7 4.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) NOA36 PF06524.7 ETO35576.1 - 1.6 7.9 17.7 2.8 7.1 12.2 1.4 1 0 0 1 1 1 0 NOA36 protein IFT57 PF10498.4 ETO35576.1 - 1.8 7.1 9.3 3.4 6.3 6.4 1.5 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 FAM176 PF14851.1 ETO35576.1 - 2 8.0 5.8 4.3 6.9 4.0 1.7 1 0 0 1 1 1 0 FAM176 family eIF-3c_N PF05470.7 ETO35576.1 - 2.8 5.9 8.6 3.7 5.5 5.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus BUD22 PF09073.5 ETO35576.1 - 3.1 6.7 16.1 0.037 13.0 5.9 1.8 2 0 0 2 2 2 0 BUD22 Sporozoite_P67 PF05642.6 ETO35576.1 - 3.2 5.4 6.4 5 4.8 4.4 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen YL1 PF05764.8 ETO35576.1 - 7.2 6.1 26.9 17 4.9 18.7 1.7 1 1 0 1 1 1 0 YL1 nuclear protein Dicty_REP PF05086.7 ETO35576.1 - 10 3.7 15.0 0.35 8.5 6.4 1.4 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Phage_sheath_1 PF04984.9 ETO35577.1 - 0.11 10.9 0.0 0.39 9.0 0.0 1.7 2 0 0 2 2 2 0 Phage tail sheath protein AAA PF00004.24 ETO35579.1 - 1.8e-07 31.4 0.0 5.1e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 ETO35579.1 - 2.8e-06 26.3 0.2 0.00015 20.5 0.0 2.6 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 ETO35579.1 - 8.8e-06 25.3 0.0 1.9e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 ETO35579.1 - 9.9e-06 26.3 0.0 4.2e-05 24.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 ETO35579.1 - 5.1e-05 22.4 0.0 0.0001 21.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 ETO35579.1 - 0.00036 20.5 0.0 0.0011 18.9 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 ETO35579.1 - 0.00054 20.2 0.0 0.00054 20.2 0.0 2.8 4 1 0 4 4 3 1 AAA domain AAA_33 PF13671.1 ETO35579.1 - 0.0013 18.6 0.0 0.0031 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 ETO35579.1 - 0.0017 17.4 0.0 0.0034 16.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_5 PF07728.9 ETO35579.1 - 0.0023 17.6 0.0 0.008 15.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 ETO35579.1 - 0.0023 17.8 0.0 0.0091 15.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 ETO35579.1 - 0.0046 16.8 0.0 0.48 10.2 0.0 2.7 2 0 0 2 2 2 1 Shikimate kinase NACHT PF05729.7 ETO35579.1 - 0.011 15.4 0.0 0.031 13.9 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.1 ETO35579.1 - 0.013 14.9 0.0 0.03 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 ETO35579.1 - 0.014 15.5 0.0 0.06 13.5 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 ETO35579.1 - 0.023 14.6 0.0 0.059 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 ETO35579.1 - 0.023 14.4 0.1 0.08 12.6 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA_22 PF13401.1 ETO35579.1 - 0.027 14.5 0.0 0.092 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 ETO35579.1 - 0.029 13.5 0.1 0.66 9.0 0.0 2.2 2 0 0 2 2 2 0 KaiC TIP49 PF06068.8 ETO35579.1 - 0.034 12.8 0.0 0.067 11.8 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 ETO35579.1 - 0.047 12.8 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 ETO35579.1 - 0.054 13.1 0.0 0.22 11.1 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase ABC_tran PF00005.22 ETO35579.1 - 0.061 13.6 0.0 0.061 13.6 0.0 2.5 3 1 0 3 3 3 0 ABC transporter UPF0079 PF02367.12 ETO35579.1 - 0.094 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 ETO35579.1 - 0.31 11.3 0.0 0.31 11.3 0.0 2.9 2 1 0 2 2 1 0 AAA domain PEX11 PF05648.9 ETO35579.1 - 0.41 9.8 3.9 1.9 7.7 1.5 2.4 1 1 1 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) AAA_11 PF13086.1 ETO35579.1 - 5.1 6.5 10.2 1.1 8.8 0.0 2.9 1 1 1 2 2 2 0 AAA domain AAA PF00004.24 ETO35580.1 - 0.036 14.2 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Chorein_N PF12624.2 ETO35581.1 - 7e-08 32.0 0.2 7e-08 32.0 0.1 1.7 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Nucleoplasmin PF03066.10 ETO35581.1 - 0.066 12.7 3.4 0.087 12.3 2.3 1.3 1 0 0 1 1 1 0 Nucleoplasmin ANAPC15 PF15243.1 ETO35581.1 - 0.33 11.0 7.7 0.57 10.2 5.4 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 NOA36 PF06524.7 ETO35581.1 - 0.35 10.1 5.8 0.41 9.8 4.0 1.1 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.1 ETO35581.1 - 0.42 10.9 8.8 0.66 10.3 6.1 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Yippee-Mis18 PF03226.9 ETO35582.1 - 3.2e-16 59.1 5.6 1.2e-15 57.3 3.9 2.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly WD40 PF00400.27 ETO35583.1 - 2.1e-09 36.8 2.2 5.7e-05 22.8 0.0 3.9 5 1 0 5 5 5 2 WD domain, G-beta repeat Mid2 PF04478.7 ETO35583.1 - 0.0062 15.9 1.9 0.34 10.3 0.1 2.9 2 1 1 3 3 3 2 Mid2 like cell wall stress sensor Rad51 PF08423.6 ETO35584.1 - 7.6e-16 57.7 0.0 1.9e-07 30.2 0.0 2.1 2 0 0 2 2 2 2 Rad51 AAA_25 PF13481.1 ETO35584.1 - 3.1e-06 26.7 0.0 1.7e-05 24.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 ETO35584.1 - 4.8e-05 22.5 1.1 0.00015 20.9 0.0 2.2 2 1 1 3 3 3 1 KaiC AAA_22 PF13401.1 ETO35584.1 - 0.00034 20.7 0.1 0.0029 17.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.10 ETO35584.1 - 0.0028 16.5 0.3 0.076 11.8 0.2 2.3 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_33 PF13671.1 ETO35584.1 - 0.024 14.5 0.1 0.059 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 ETO35584.1 - 0.088 12.2 0.3 0.24 10.8 0.2 1.7 1 1 0 1 1 1 0 FtsK/SpoIIIE family RecA PF00154.16 ETO35584.1 - 0.12 11.4 0.1 0.23 10.4 0.0 1.4 2 0 0 2 2 2 0 recA bacterial DNA recombination protein DUF3458 PF11940.3 ETO35585.1 - 4.4e-56 190.2 0.0 5.7e-56 189.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) U-box PF04564.10 ETO35587.1 - 2.9e-14 52.7 0.1 4.8e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.3 ETO35587.1 - 0.015 14.8 0.0 0.04 13.4 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-TRAF PF02176.13 ETO35588.1 - 1.1e-05 25.6 2.0 2.6e-05 24.5 0.5 2.4 2 0 0 2 2 2 1 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 ETO35588.1 - 1.3 9.0 10.8 4.3 7.4 0.1 3.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) UBACT PF02134.16 ETO35590.1 - 1.7e-18 65.9 1.7 2.7e-18 65.2 0.1 2.0 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 ETO35590.1 - 1.2e-11 43.7 1.1 1.2e-11 43.7 0.8 2.6 3 0 0 3 3 3 1 Ubiquitin-activating enzyme active site E2_bind PF08825.5 ETO35590.1 - 6.1e-07 29.1 0.0 1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain ThiF PF00899.16 ETO35590.1 - 2.8e-06 27.1 0.0 4.7e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 ThiF family UAE_UbL PF14732.1 ETO35590.1 - 0.00011 22.2 0.0 0.00019 21.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain MoeZ_MoeB PF05237.8 ETO35590.1 - 0.0089 15.6 0.3 0.11 12.0 0.0 2.3 2 0 0 2 2 2 1 MoeZ/MoeB domain WD40 PF00400.27 ETO35591.1 - 1.2e-07 31.3 0.5 2.7e-07 30.2 0.4 1.7 1 0 0 1 1 1 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO35591.1 - 3.1e-05 22.3 0.1 4.1e-05 21.9 0.1 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 DUF4279 PF14106.1 ETO35592.1 - 0.078 12.8 0.9 0.19 11.6 0.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4279) Cytochrom_B_C PF00032.12 ETO35593.1 - 0.25 11.5 4.0 0.42 10.8 0.0 2.3 2 1 1 3 3 3 0 Cytochrome b(C-terminal)/b6/petD HIRAN PF08797.6 ETO35594.1 - 8e-08 32.1 0.0 1.4e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 HIRAN domain Cas_Cmr5 PF09701.5 ETO35594.1 - 0.066 13.3 2.4 0.32 11.1 1.7 2.1 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr5) RVT_3 PF13456.1 ETO35594.1 - 0.074 12.8 0.3 0.29 10.9 0.1 2.0 1 1 1 2 2 2 0 Reverse transcriptase-like Peptidase_M43 PF05572.8 ETO35594.1 - 0.18 11.4 4.2 0.069 12.7 0.6 2.1 2 1 0 2 2 2 0 Pregnancy-associated plasma protein-A S_layer_N PF05123.7 ETO35594.1 - 1.6 8.3 5.4 2.2 7.8 3.7 1.2 1 0 0 1 1 1 0 S-layer like family, N-terminal region TFIID_20kDa PF03847.8 ETO35595.1 - 0.044 14.0 0.1 0.044 14.0 0.1 2.7 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A DUF2052 PF09747.4 ETO35597.1 - 0.0048 16.8 16.1 0.0062 16.4 11.2 1.0 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Spore_coat_CotO PF14153.1 ETO35597.1 - 0.0067 15.8 17.8 0.0073 15.7 12.4 1.0 1 0 0 1 1 1 1 Spore coat protein CotO DUF1510 PF07423.6 ETO35597.1 - 0.015 14.7 23.5 0.017 14.4 16.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Zip PF02535.17 ETO35597.1 - 0.018 14.0 2.9 0.019 14.0 2.0 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.8 ETO35597.1 - 0.086 11.3 14.9 0.096 11.1 10.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.7 ETO35597.1 - 0.18 11.6 17.8 0.19 11.6 12.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PPP4R2 PF09184.6 ETO35597.1 - 0.23 10.9 18.0 0.26 10.8 12.5 1.0 1 0 0 1 1 1 0 PPP4R2 Raftlin PF15250.1 ETO35597.1 - 0.24 9.8 9.6 0.26 9.7 6.6 1.0 1 0 0 1 1 1 0 Raftlin Rtf2 PF04641.7 ETO35597.1 - 0.3 10.2 17.5 0.32 10.1 12.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DDHD PF02862.12 ETO35597.1 - 0.31 10.7 15.1 0.35 10.6 10.4 1.0 1 0 0 1 1 1 0 DDHD domain Vfa1 PF08432.5 ETO35597.1 - 0.33 10.9 19.9 0.51 10.3 13.8 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Trypan_PARP PF05887.6 ETO35597.1 - 0.47 10.2 9.9 0.58 9.9 6.9 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Herpes_env PF01673.13 ETO35597.1 - 0.55 8.7 8.1 0.59 8.6 5.6 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Pox_Ag35 PF03286.9 ETO35597.1 - 0.6 9.5 20.4 0.79 9.2 14.1 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DHHW PF14286.1 ETO35597.1 - 0.61 9.3 10.1 0.67 9.2 7.0 1.0 1 0 0 1 1 1 0 DHHW protein DUF913 PF06025.7 ETO35597.1 - 0.62 8.7 6.7 0.66 8.6 4.7 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Tim54 PF11711.3 ETO35597.1 - 0.64 8.5 13.8 0.73 8.3 9.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 BSMAP PF12280.3 ETO35597.1 - 0.68 9.7 5.1 0.78 9.5 3.5 1.2 1 0 0 1 1 1 0 Brain specific membrane anchored protein SprA-related PF12118.3 ETO35597.1 - 0.68 9.2 17.6 0.78 9.0 12.2 1.0 1 0 0 1 1 1 0 SprA-related family CDC45 PF02724.9 ETO35597.1 - 0.95 7.4 14.6 1 7.3 10.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Serinc PF03348.10 ETO35597.1 - 1.2 7.7 5.9 1.4 7.5 4.1 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) MDFI PF15316.1 ETO35597.1 - 1.2 9.0 3.4 1.3 8.9 2.4 1.1 1 0 0 1 1 1 0 MyoD family inhibitor PBP1_TM PF14812.1 ETO35597.1 - 1.7 9.0 21.6 4.3 7.7 14.9 1.6 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RNase_H2-Ydr279 PF09468.5 ETO35597.1 - 1.7 7.7 18.5 2.1 7.4 12.8 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) RP-C_C PF11800.3 ETO35597.1 - 1.9 8.1 10.1 2.8 7.5 7.0 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF2146 PF10220.4 ETO35597.1 - 2 6.3 9.9 2.1 6.2 6.9 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) TT_ORF1 PF02956.9 ETO35597.1 - 2 6.7 9.1 2.2 6.6 6.3 1.0 1 0 0 1 1 1 0 TT viral orf 1 TLP-20 PF06088.6 ETO35597.1 - 2.2 7.9 14.1 2.6 7.7 9.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) U79_P34 PF03064.11 ETO35597.1 - 2.3 7.6 15.7 2.9 7.3 10.9 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF2201_N PF13203.1 ETO35597.1 - 2.7 7.1 10.1 3 6.9 7.0 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF262 PF03235.9 ETO35597.1 - 2.8 7.8 10.3 3.3 7.6 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 BTV_NS2 PF04514.7 ETO35597.1 - 2.8 6.7 13.7 3.3 6.4 9.5 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CRT10 PF08728.5 ETO35597.1 - 3.4 5.5 8.8 3.5 5.4 6.1 1.0 1 0 0 1 1 1 0 CRT10 Daxx PF03344.10 ETO35597.1 - 3.6 5.9 21.0 4.4 5.6 14.6 1.0 1 0 0 1 1 1 0 Daxx Family DUF4220 PF13968.1 ETO35597.1 - 3.7 6.5 7.4 4.1 6.3 5.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) AP-5_subunit_s1 PF15001.1 ETO35597.1 - 3.8 7.4 6.7 5 7.0 4.6 1.1 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 SAPS PF04499.10 ETO35597.1 - 4.3 5.8 18.4 5.3 5.5 12.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein IncA PF04156.9 ETO35597.1 - 4.3 6.8 7.8 4.7 6.7 5.4 1.1 1 0 0 1 1 1 0 IncA protein Ycf1 PF05758.7 ETO35597.1 - 4.6 4.8 14.9 5 4.7 10.3 1.0 1 0 0 1 1 1 0 Ycf1 Herpes_DNAp_acc PF04929.7 ETO35597.1 - 4.7 6.0 14.4 5.9 5.7 10.0 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor FAM60A PF15396.1 ETO35597.1 - 4.9 6.8 11.1 5.7 6.6 7.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A SID-1_RNA_chan PF13965.1 ETO35597.1 - 5.2 5.1 6.2 5.6 5.0 4.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Hid1 PF12722.2 ETO35597.1 - 5.2 4.6 14.8 6.1 4.3 10.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NARP1 PF12569.3 ETO35597.1 - 6.1 5.4 20.3 7 5.2 14.1 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Paramyxo_ncap PF00973.14 ETO35597.1 - 6.2 5.3 9.3 6.9 5.2 6.4 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein MIP-T3 PF10243.4 ETO35597.1 - 6.3 5.1 32.3 7.8 4.8 22.4 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF4407 PF14362.1 ETO35597.1 - 6.3 5.6 12.0 7.8 5.3 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.12 ETO35597.1 - 7 5.3 8.7 8 5.1 6.0 1.0 1 0 0 1 1 1 0 Presenilin Cellulose_synt PF03552.9 ETO35597.1 - 7 4.8 8.5 7.5 4.7 5.9 1.0 1 0 0 1 1 1 0 Cellulose synthase GCD14 PF08704.5 ETO35597.1 - 7.1 6.0 7.4 8.2 5.8 5.1 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DUF2413 PF10310.4 ETO35597.1 - 7.9 5.1 20.8 9.4 4.9 14.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) eIF-3c_N PF05470.7 ETO35597.1 - 8.4 4.3 17.3 9.8 4.1 12.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DDRGK PF09756.4 ETO35597.1 - 9.8 5.5 27.3 13 5.1 18.9 1.1 1 0 0 1 1 1 0 DDRGK domain Patched PF02460.13 ETO35598.1 - 6e-24 84.0 0.2 8.4e-24 83.5 0.2 1.1 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 ETO35598.1 - 1.2e-23 83.3 2.4 2e-23 82.5 1.7 1.3 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation MgtE PF01769.11 ETO35598.1 - 0.034 14.4 0.9 0.068 13.4 0.6 1.4 1 0 0 1 1 1 0 Divalent cation transporter Patched PF02460.13 ETO35599.1 - 3.8e-12 44.9 12.5 5.1e-12 44.5 8.7 1.1 1 0 0 1 1 1 1 Patched family HRM PF02793.17 ETO35599.1 - 7 6.7 22.7 0.039 13.9 0.9 5.1 3 2 1 4 4 4 0 Hormone receptor domain CDC45 PF02724.9 ETO35600.1 - 0.00011 20.4 0.3 0.00016 19.8 0.2 1.2 1 0 0 1 1 1 1 CDC45-like protein DUF3938 PF13074.1 ETO35600.1 - 0.38 10.6 6.6 5.1 6.9 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3938) Daxx PF03344.10 ETO35600.1 - 0.66 8.3 9.0 0.95 7.8 6.2 1.1 1 0 0 1 1 1 0 Daxx Family Spore_YhcN_YlaJ PF09580.5 ETO35600.1 - 1.7 8.7 18.9 13 5.8 10.8 2.1 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Kelch_4 PF13418.1 ETO35601.1 - 4e-05 23.3 0.1 0.067 12.9 0.0 2.8 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO35601.1 - 0.00069 19.1 3.3 0.0036 16.8 0.4 2.6 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 ETO35601.1 - 0.0016 18.5 0.4 0.39 10.9 0.1 2.5 1 1 1 2 2 2 2 Kelch motif Kelch_2 PF07646.10 ETO35601.1 - 0.0022 17.7 0.1 2.1 8.2 0.0 2.9 2 0 0 2 2 2 2 Kelch motif Interfer-bind PF09294.5 ETO35601.1 - 0.024 14.6 0.7 0.63 10.1 0.0 2.3 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III Kelch_5 PF13854.1 ETO35601.1 - 0.067 13.1 0.6 6.3 6.8 0.6 2.9 3 0 0 3 3 3 0 Kelch motif Tox-SHH PF15652.1 ETO35604.1 - 0.078 13.5 0.5 0.12 12.9 0.3 1.3 1 0 0 1 1 1 0 HNH/Endo VII superfamily toxin with a SHH signature ASD2 PF08687.6 ETO35604.1 - 0.15 11.3 2.3 0.17 11.2 1.6 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 GTP_EFTU PF00009.22 ETO35605.1 - 4.8e-20 71.7 0.1 2.7e-13 49.7 0.0 2.0 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 ETO35605.1 - 0.045 13.7 0.0 0.28 11.1 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase CENP-B_dimeris PF09026.5 ETO35606.1 - 0.0022 18.2 2.5 0.0029 17.8 1.8 1.2 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 ETO35606.1 - 0.0049 16.5 1.6 0.0052 16.4 1.1 1.1 1 0 0 1 1 1 1 Sigma-70, non-essential region DUF4484 PF14831.1 ETO35606.1 - 0.023 14.8 1.5 0.024 14.7 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) DUF2457 PF10446.4 ETO35606.1 - 0.03 13.0 7.8 0.031 13.0 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 ETO35606.1 - 0.032 13.7 5.4 0.036 13.5 3.8 1.2 1 0 0 1 1 1 0 Nucleoplasmin DUF4611 PF15387.1 ETO35606.1 - 0.035 14.2 3.0 0.056 13.5 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) RXT2_N PF08595.6 ETO35606.1 - 0.041 13.6 2.2 0.048 13.4 1.6 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.7 ETO35606.1 - 0.12 11.6 5.3 0.15 11.3 3.6 1.1 1 0 0 1 1 1 0 NOA36 protein BTV_NS2 PF04514.7 ETO35606.1 - 0.12 11.1 0.8 0.13 11.1 0.5 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Cwf_Cwc_15 PF04889.7 ETO35606.1 - 0.67 9.6 6.0 0.77 9.4 4.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein JAB PF01398.16 ETO35607.1 - 1.8e-10 40.5 0.1 5.8e-10 38.9 0.0 1.8 2 1 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 ETO35607.1 - 4.7e-08 33.1 0.1 9.9e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Bd3614_N PF14442.1 ETO35607.1 - 0.062 13.2 0.1 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal PUB PF09409.5 ETO35608.1 - 0.017 14.9 1.7 0.11 12.3 0.5 2.7 2 1 0 2 2 2 0 PUB domain AAA_24 PF13479.1 ETO35608.1 - 0.023 14.2 1.3 0.1 12.2 0.5 2.2 1 1 1 2 2 2 0 AAA domain CW_binding_1 PF01473.15 ETO35608.1 - 0.51 10.5 6.5 0.14 12.2 2.1 2.0 2 0 0 2 2 2 0 Putative cell wall binding repeat Ras PF00071.17 ETO35609.1 - 1.2e-43 148.3 6.5 1.8e-31 108.7 1.2 2.7 2 1 0 2 2 2 2 Ras family Miro PF08477.8 ETO35609.1 - 1.6e-11 44.7 4.4 7.1e-07 29.7 1.0 2.9 1 1 1 2 2 2 2 Miro-like protein Arf PF00025.16 ETO35609.1 - 1.1e-06 28.0 1.4 0.00015 21.0 0.2 2.4 2 1 0 2 2 2 2 ADP-ribosylation factor family DNA_ligase_A_M PF01068.16 ETO35609.1 - 0.52 9.6 10.9 0.67 9.2 0.1 2.4 2 1 1 3 3 3 0 ATP dependent DNA ligase domain RNA_pol_Rpc82 PF05645.8 ETO35610.1 - 0.027 13.9 8.0 0.034 13.6 5.5 1.1 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 Daxx PF03344.10 ETO35610.1 - 0.05 12.0 8.1 0.052 12.0 5.6 1.0 1 0 0 1 1 1 0 Daxx Family Vma12 PF11712.3 ETO35610.1 - 0.06 13.0 4.1 0.095 12.4 2.8 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase BTV_NS2 PF04514.7 ETO35610.1 - 0.066 12.0 14.6 0.072 11.9 10.1 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DHHW PF14286.1 ETO35610.1 - 0.092 12.0 5.2 0.1 11.8 3.6 1.1 1 0 0 1 1 1 0 DHHW protein TIR-like PF10137.4 ETO35610.1 - 0.11 12.1 1.1 0.32 10.6 0.0 2.0 2 1 0 2 2 2 0 Predicted nucleotide-binding protein containing TIR-like domain CDC45 PF02724.9 ETO35610.1 - 0.2 9.6 6.6 0.23 9.4 4.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Init_tRNA_PT PF04179.7 ETO35610.1 - 0.45 9.3 10.0 0.55 9.0 6.9 1.0 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Suc_Fer-like PF06999.7 ETO35610.1 - 0.57 10.1 4.6 0.66 9.9 3.2 1.0 1 0 0 1 1 1 0 Sucrase/ferredoxin-like Rtf2 PF04641.7 ETO35610.1 - 0.82 8.8 11.7 0.99 8.5 8.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger CLP_protease PF00574.18 ETO35610.1 - 0.85 9.2 4.3 1.4 8.5 3.0 1.3 1 0 0 1 1 1 0 Clp protease DUF3035 PF11233.3 ETO35610.1 - 0.86 9.6 3.1 1.3 9.0 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) DUF4355 PF14265.1 ETO35610.1 - 1.7 8.5 22.2 0.13 12.2 8.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) NYD-SP12_N PF15015.1 ETO35610.1 - 2.7 6.1 9.2 2.4 6.2 6.4 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal G-alpha PF00503.15 ETO35612.1 - 1.3e-33 116.3 5.6 1.4e-33 116.2 3.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO35612.1 - 0.029 13.6 0.2 0.067 12.4 0.1 1.6 1 1 0 1 1 1 0 ADP-ribosylation factor family NACHT PF05729.7 ETO35613.1 - 1e-08 35.0 0.0 1.9e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETO35613.1 - 0.0001 22.4 0.0 0.00037 20.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETO35613.1 - 0.00016 22.0 0.0 0.00016 22.0 0.0 2.4 3 1 0 3 3 3 1 AAA domain AAA_17 PF13207.1 ETO35613.1 - 0.0018 19.0 0.1 0.018 15.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 ETO35613.1 - 0.0037 16.9 0.1 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 ETO35613.1 - 0.012 15.7 0.7 0.077 13.1 0.1 2.5 2 1 1 3 3 3 0 RNA helicase PRK PF00485.13 ETO35613.1 - 0.018 14.6 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA PF00004.24 ETO35613.1 - 0.036 14.2 0.0 0.074 13.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) VirE PF05272.6 ETO35613.1 - 0.042 13.3 0.0 0.078 12.4 0.0 1.5 1 0 0 1 1 1 0 Virulence-associated protein E AAA_33 PF13671.1 ETO35613.1 - 0.085 12.7 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETO35613.1 - 0.12 12.3 0.2 1.7 8.5 0.0 2.5 2 1 1 3 3 3 0 AAA ATPase domain ABC_tran PF00005.22 ETO35613.1 - 0.14 12.4 0.3 0.35 11.1 0.1 1.9 2 1 0 2 2 2 0 ABC transporter TcdB_N PF12918.2 ETO35613.1 - 6.1 7.0 7.2 5.7 7.0 0.3 3.3 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain WD40 PF00400.27 ETO35615.1 - 3.5e-131 422.9 32.3 5.2e-11 41.9 0.0 15.7 15 1 1 16 16 16 13 WD domain, G-beta repeat Nbas_N PF15492.1 ETO35615.1 - 3.6e-07 29.5 11.7 0.063 12.3 0.1 6.5 3 2 3 6 6 6 4 Neuroblastoma-amplified sequence, N terminal Pentapeptide_4 PF13599.1 ETO35615.1 - 1.9e-05 24.4 0.6 5.4e-05 22.9 0.4 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 ETO35615.1 - 6.2e-05 22.1 0.7 0.00014 21.0 0.5 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 ETO35615.1 - 0.00064 19.5 0.3 0.00064 19.5 0.2 2.4 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) Cytochrom_D1 PF02239.11 ETO35615.1 - 0.0026 16.1 4.8 0.49 8.6 0.0 4.2 4 1 0 5 5 5 2 Cytochrome D1 heme domain PD40 PF07676.7 ETO35615.1 - 9.7 5.9 20.3 44 3.8 0.0 7.6 9 0 0 9 9 9 0 WD40-like Beta Propeller Repeat LDB19 PF13002.2 ETO35616.1 - 0.14 11.6 0.1 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Arrestin_N terminal like C2 PF00168.25 ETO35618.1 - 7e-14 51.4 1.1 7.2e-08 32.1 0.0 3.7 3 1 0 3 3 3 3 C2 domain FerI PF08151.7 ETO35618.1 - 8.3e-12 44.9 0.0 3.5e-11 42.9 0.0 2.1 2 0 0 2 2 2 1 FerI (NUC094) domain AnfO_nitrog PF09582.5 ETO35619.1 - 0.095 11.8 1.7 0.11 11.6 1.2 1.1 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) YqfQ PF14181.1 ETO35619.1 - 1.6 8.7 6.4 1.8 8.5 4.5 1.1 1 0 0 1 1 1 0 YqfQ-like protein Sec62 PF03839.11 ETO35619.1 - 3.2 7.1 5.8 2.9 7.2 4.0 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 IU_nuc_hydro PF01156.14 ETO35620.1 - 1.5e-11 44.1 0.0 1.6e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase IU_nuc_hydro PF01156.14 ETO35621.1 - 4.1e-22 78.7 0.0 4.7e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Adap_comp_sub PF00928.16 ETO35622.1 - 1.8e-08 33.7 0.0 2.3e-07 30.2 0.0 2.0 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 ETO35623.1 - 0.091 12.4 0.8 0.16 11.6 0.5 1.5 1 1 0 1 1 1 0 Clathrin adaptor complex small chain GNT-I PF03071.10 ETO35624.1 - 6.7e-06 24.9 0.1 8.6e-06 24.5 0.0 1.1 1 0 0 1 1 1 1 GNT-I family Glycos_transf_2 PF00535.21 ETO35624.1 - 0.00089 18.9 0.3 0.0018 17.9 0.2 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF4131 PF13567.1 ETO35624.1 - 0.026 13.9 0.1 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Glyco_tranf_2_3 PF13641.1 ETO35624.1 - 0.043 13.6 0.0 0.058 13.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 GNT-I PF03071.10 ETO35625.1 - 1.3e-23 83.3 0.6 1.8e-23 82.8 0.4 1.1 1 0 0 1 1 1 1 GNT-I family Glyco_transf_18 PF15024.1 ETO35625.1 - 0.00033 19.1 4.8 0.00044 18.7 3.3 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 18 WD40 PF00400.27 ETO35626.1 - 2.2e-30 103.4 8.3 9.3e-12 44.3 0.3 4.2 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO35626.1 - 0.011 13.8 0.3 2.1 6.3 0.1 2.8 1 1 2 3 3 3 0 Nucleoporin Nup120/160 DUF1900 PF08954.6 ETO35626.1 - 0.084 12.4 0.0 0.18 11.3 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1900) Kelch_1 PF01344.20 ETO35627.1 - 6.2e-05 22.4 0.2 0.00038 19.9 0.0 2.2 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO35627.1 - 0.095 12.8 0.1 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO35627.1 - 0.14 12.1 3.7 0.6 10.1 1.6 2.4 2 1 0 2 2 2 0 Kelch motif ORF6N PF10543.4 ETO35628.1 - 0.15 12.0 1.0 0.42 10.6 0.2 2.3 2 1 0 2 2 2 0 ORF6N domain DapB_N PF01113.15 ETO35629.1 - 0.093 12.6 0.0 0.48 10.3 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus DLD PF14878.1 ETO35629.1 - 0.34 11.0 2.0 0.92 9.6 0.1 2.1 2 0 0 2 2 2 0 Death-like domain of SPT6 DARPP-32 PF05395.7 ETO35630.1 - 3.5 7.7 6.2 4.8 7.3 4.3 1.1 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 dUTPase_2 PF08761.6 ETO35631.1 - 0.13 12.3 2.7 0.28 11.2 1.8 1.6 1 1 0 1 1 1 0 dUTPase AAA PF00004.24 ETO35633.1 - 4.2e-09 36.6 0.0 0.00023 21.3 0.0 3.1 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETO35633.1 - 4.1e-07 29.8 0.1 0.0078 15.9 0.0 4.6 4 1 0 4 4 4 2 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 ETO35633.1 - 1.3e-06 28.7 0.0 1.1e-05 25.7 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.1 ETO35633.1 - 1.7e-06 28.2 0.0 0.096 12.8 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 ETO35633.1 - 0.00059 19.8 0.0 0.062 13.2 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 ETO35633.1 - 0.00064 18.9 0.0 0.0016 17.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Sigma54_activ_2 PF14532.1 ETO35633.1 - 0.0033 17.4 0.0 0.1 12.6 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain Miro PF08477.8 ETO35633.1 - 0.015 15.7 0.0 0.081 13.4 0.0 2.4 1 0 0 1 1 1 0 Miro-like protein Sigma54_activat PF00158.21 ETO35633.1 - 0.016 14.7 0.0 0.73 9.2 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain PduV-EutP PF10662.4 ETO35633.1 - 0.022 14.2 0.1 0.1 12.0 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.1 ETO35633.1 - 0.054 13.2 0.0 9.2 6.0 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain Mg_chelatase PF01078.16 ETO35633.1 - 0.16 11.1 0.1 12 4.9 0.0 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 ETO35633.1 - 0.18 11.1 0.0 4.8 6.5 0.0 3.3 4 0 0 4 4 4 0 AAA domain eRF1_2 PF03464.10 ETO35633.1 - 0.58 10.4 3.4 0.45 10.8 0.1 2.5 3 0 0 3 3 1 0 eRF1 domain 2 AAA_23 PF13476.1 ETO35633.1 - 3.3 7.9 11.4 0.18 12.1 0.4 3.5 3 1 0 3 3 3 0 AAA domain Spore_coat_CotO PF14153.1 ETO35634.1 - 0.013 14.9 2.4 0.016 14.6 1.7 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Tom37_C PF11801.3 ETO35634.1 - 0.12 12.1 0.7 0.18 11.6 0.5 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain COPI_C PF06957.6 ETO35634.1 - 0.17 10.3 3.6 0.22 10.0 2.5 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus TRAP_alpha PF03896.11 ETO35634.1 - 0.48 9.3 4.6 0.53 9.2 3.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit ISG65-75 PF11727.3 ETO35634.1 - 0.73 8.8 8.9 1.1 8.2 6.1 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein Daxx PF03344.10 ETO35634.1 - 1 7.7 11.9 1.2 7.5 8.2 1.1 1 0 0 1 1 1 0 Daxx Family SAB PF04382.8 ETO35635.1 - 0.0089 15.6 4.4 0.022 14.4 2.6 2.1 1 1 1 2 2 2 1 SAB domain ATG16 PF08614.6 ETO35635.1 - 0.07 12.9 27.5 0.076 12.8 12.1 2.3 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 ETO35635.1 - 0.6 9.2 13.1 0.86 8.7 7.5 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DivIVA PF05103.8 ETO35635.1 - 1 9.3 26.9 0.053 13.5 5.1 3.2 2 1 1 3 3 3 0 DivIVA protein V_ATPase_I PF01496.14 ETO35635.1 - 1.2 6.8 19.4 1.8 6.3 13.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 ETO35635.1 - 1.4 9.3 26.2 0.36 11.1 6.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF972) DUF641 PF04859.7 ETO35635.1 - 2.5 7.8 15.5 0.21 11.3 6.0 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) IncA PF04156.9 ETO35635.1 - 3.5 7.1 27.3 2.3 7.7 13.0 2.3 1 1 1 2 2 2 0 IncA protein TMF_DNA_bd PF12329.3 ETO35635.1 - 7.6 6.4 31.7 0.41 10.4 9.2 3.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF1431 PF07248.7 ETO35636.1 - 0.29 11.0 1.8 0.33 10.9 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1431) Cytochrom_C1 PF02167.10 ETO35637.1 - 7.5e-24 84.6 0.0 9.7e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 ETO35637.1 - 0.00015 21.8 0.1 0.00022 21.3 0.0 1.5 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 ETO35637.1 - 0.015 16.1 0.0 0.028 15.2 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c DivIC PF04977.10 ETO35639.1 - 0.0048 16.3 3.1 0.0048 16.3 2.1 2.4 2 1 1 3 3 3 1 Septum formation initiator Baculo_LEF-10 PF07206.6 ETO35639.1 - 0.038 13.6 0.2 0.099 12.3 0.1 1.7 1 0 0 1 1 1 0 Baculovirus late expression factor 10 (LEF-10) PINIT PF14324.1 ETO35639.1 - 0.48 10.5 8.0 0.14 12.2 2.7 2.2 2 1 1 3 3 3 0 PINIT domain WD40 PF00400.27 ETO35640.1 - 2.6e-25 87.3 0.4 1.6e-11 43.6 0.1 4.1 3 0 0 3 3 3 3 WD domain, G-beta repeat Kelch_1 PF01344.20 ETO35640.1 - 1.1e-06 28.1 0.6 0.03 13.8 0.0 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO35640.1 - 6.4e-06 25.7 3.6 0.048 13.4 0.0 4.8 5 0 0 5 5 5 1 Kelch motif Kelch_5 PF13854.1 ETO35640.1 - 0.003 17.4 0.0 11 6.0 0.0 4.5 4 0 0 4 4 4 1 Kelch motif Cytochrom_D1 PF02239.11 ETO35640.1 - 0.0061 14.8 0.1 0.011 14.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome D1 heme domain Kelch_6 PF13964.1 ETO35640.1 - 0.012 15.7 2.8 48 4.3 0.1 4.8 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.1 ETO35640.1 - 0.022 14.5 5.3 9.8 6.0 0.0 4.3 5 0 0 5 5 5 0 Galactose oxidase, central domain Nucleoporin_N PF08801.6 ETO35640.1 - 0.023 13.4 1.0 0.6 8.7 0.0 2.2 1 1 1 2 2 2 0 Nup133 N terminal like Nup160 PF11715.3 ETO35640.1 - 0.037 12.1 0.9 1.8 6.6 0.1 2.1 1 1 0 2 2 2 0 Nucleoporin Nup120/160 Kelch_3 PF13415.1 ETO35640.1 - 0.16 12.1 0.3 35 4.7 0.0 4.0 4 0 0 4 4 4 0 Galactose oxidase, central domain BLOC1_2 PF10046.4 ETO35643.1 - 1.1e-18 67.1 4.1 1.1e-18 67.1 2.9 2.1 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 EST1 PF10374.4 ETO35643.1 - 0.034 14.1 1.9 0.13 12.2 1.3 1.9 1 1 0 1 1 1 0 Telomerase activating protein Est1 SSP160 PF06933.6 ETO35643.1 - 0.052 11.5 1.6 0.06 11.3 1.1 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 BRF1 PF07741.8 ETO35643.1 - 0.065 13.4 2.8 0.13 12.4 2.0 1.5 1 0 0 1 1 1 0 Brf1-like TBP-binding domain YflT PF11181.3 ETO35643.1 - 0.18 11.9 2.1 0.15 12.1 0.3 1.7 1 1 0 1 1 1 0 Heat induced stress protein YflT NOA36 PF06524.7 ETO35644.1 - 0.0027 17.0 2.7 0.0045 16.2 1.9 1.4 1 0 0 1 1 1 1 NOA36 protein APC_CDC26 PF10471.4 ETO35644.1 - 2.9 8.7 10.6 0.94 10.2 4.8 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF2457 PF10446.4 ETO35644.1 - 7.4 5.1 19.6 11 4.5 13.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Helicase_C PF00271.26 ETO35645.1 - 1.1e-20 73.2 0.0 2.5e-20 72.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETO35645.1 - 3.2e-18 65.8 0.0 9.7e-15 54.4 0.0 2.8 2 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C_2 PF13307.1 ETO35645.1 - 0.00026 20.9 0.5 0.00061 19.7 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain Metal_resist PF13801.1 ETO35645.1 - 0.15 12.0 2.1 0.29 11.1 1.4 1.4 1 0 0 1 1 1 0 Heavy-metal resistance PfkB PF00294.19 ETO35646.1 - 7.1e-36 123.8 0.0 8.8e-36 123.5 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 ETO35646.1 - 9.4e-06 24.9 0.1 2.2e-05 23.7 0.0 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Peptidase_C1_2 PF03051.10 ETO35647.1 - 1.3e-103 346.9 2.1 9.1e-79 265.0 0.2 2.0 2 0 0 2 2 2 2 Peptidase C1-like family HobA PF12163.3 ETO35647.1 - 0.075 12.3 0.9 0.16 11.2 0.1 2.0 2 1 0 2 2 2 0 DNA replication regulator Prefoldin PF02996.12 ETO35649.1 - 1.9 8.1 12.9 0.073 12.7 2.5 2.9 3 0 0 3 3 3 0 Prefoldin subunit DUF2570 PF10828.3 ETO35649.1 - 2.9 7.5 14.6 2 8.0 8.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) Kelch_6 PF13964.1 ETO35650.1 - 3.4e-07 30.1 2.9 0.11 12.7 0.2 4.2 2 2 2 4 4 4 3 Kelch motif Kelch_5 PF13854.1 ETO35650.1 - 2.3e-05 24.2 3.2 0.17 11.8 0.6 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO35650.1 - 0.00055 19.4 6.3 0.0094 15.4 0.5 3.8 3 1 1 4 4 4 1 Kelch motif SRP19 PF01922.12 ETO35651.1 - 0.06 13.9 0.0 0.073 13.6 0.0 1.2 1 0 0 1 1 1 0 SRP19 protein WD40 PF00400.27 ETO35652.1 - 1.4e-15 56.4 4.9 7.3e-11 41.5 0.6 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO35652.1 - 7.2e-05 21.1 0.1 9.6e-05 20.7 0.1 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 NhaB PF06450.7 ETO35652.1 - 0.0028 16.3 6.0 0.0032 16.1 4.2 1.1 1 0 0 1 1 1 1 Bacterial Na+/H+ antiporter B (NhaB) DUF4611 PF15387.1 ETO35653.1 - 0.0088 16.1 0.6 0.017 15.2 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) Kelch_1 PF01344.20 ETO35654.1 - 2.6e-05 23.6 4.7 4.4e-05 22.9 0.7 2.8 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETO35654.1 - 0.00011 21.9 2.0 0.0026 17.4 0.0 2.5 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO35654.1 - 0.0019 17.8 1.0 0.009 15.7 0.2 2.4 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 ETO35654.1 - 0.0028 17.7 0.8 0.042 14.0 0.1 2.4 1 1 1 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO35654.1 - 0.0049 17.0 0.1 0.013 15.6 0.0 1.7 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO35654.1 - 0.057 13.3 0.8 0.42 10.6 0.3 2.2 2 0 0 2 2 2 0 Kelch motif PUB PF09409.5 ETO35655.1 - 0.0038 16.9 0.4 0.011 15.4 0.3 1.9 1 1 0 1 1 1 1 PUB domain DUF2666 PF10869.3 ETO35655.1 - 0.019 14.9 0.7 0.044 13.7 0.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2666) WD40 PF00400.27 ETO35657.1 - 1.2e-65 215.1 14.7 7.8e-12 44.6 0.1 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO35657.1 - 2.2e-07 30.0 5.4 0.51 9.0 0.1 4.8 1 1 3 5 5 5 4 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO35657.1 - 9.5e-07 27.4 0.2 0.0036 15.6 0.1 3.2 2 1 1 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.3 ETO35657.1 - 5.1e-05 21.6 11.1 0.3 9.1 0.0 5.5 1 1 4 6 6 6 3 Nucleoporin Nup120/160 Str_synth PF03088.11 ETO35657.1 - 0.00069 19.5 0.3 1.1 9.2 0.0 4.6 2 2 3 5 5 5 1 Strictosidine synthase PQQ_2 PF13360.1 ETO35657.1 - 0.0017 17.8 0.4 0.33 10.3 0.0 2.8 1 1 1 2 2 2 2 PQQ-like domain Coatomer_WDAD PF04053.9 ETO35657.1 - 0.0082 14.9 0.4 2 7.1 0.0 2.8 1 1 1 3 3 3 1 Coatomer WD associated region USP7_C2 PF14533.1 ETO35657.1 - 0.053 12.9 0.1 8.1 5.8 0.0 3.2 3 1 0 3 3 3 0 Ubiquitin-specific protease C-terminal Proteasome_A_N PF10584.4 ETO35657.1 - 0.22 10.8 1.4 6.2 6.2 0.0 3.4 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature PD40 PF07676.7 ETO35657.1 - 0.61 9.8 2.8 20 4.9 0.1 3.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Cys_rich_VLP PF14194.1 ETO35659.1 - 0.13 12.0 1.1 0.25 11.1 0.2 1.8 2 0 0 2 2 2 0 Cysteine-rich VLP WD40 PF00400.27 ETO35661.1 - 0.021 14.7 1.5 0.93 9.4 0.1 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat NapE PF06796.6 ETO35662.1 - 0.031 13.5 0.6 0.062 12.6 0.0 1.8 2 1 0 2 2 2 0 Periplasmic nitrate reductase protein NapE Tricho_coat PF05892.6 ETO35662.1 - 0.049 12.8 0.1 0.091 11.9 0.0 1.4 1 1 0 1 1 1 0 Trichovirus coat protein ITI_HC_C PF06668.7 ETO35663.1 - 0.076 12.4 0.2 0.091 12.1 0.2 1.1 1 0 0 1 1 1 0 Inter-alpha-trypsin inhibitor heavy chain C-terminus Minor_capsid_3 PF12691.2 ETO35664.1 - 0.018 14.7 1.3 0.022 14.4 0.9 1.1 1 0 0 1 1 1 0 Minor capsid protein from bacteriophage OTOS PF15182.1 ETO35664.1 - 0.033 13.8 0.4 0.1 12.2 0.2 1.7 1 1 1 2 2 2 0 Otospiralin DUF2959 PF11172.3 ETO35666.1 - 0.025 14.3 1.7 0.044 13.5 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) NUDIX_2 PF13869.1 ETO35667.1 - 1.8e-68 229.6 0.1 1.8e-68 229.6 0.0 1.8 2 0 0 2 2 2 1 Nucleotide hydrolase BAF1_ABF1 PF04684.8 ETO35667.1 - 0.55 9.0 15.8 0.69 8.7 11.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor NIF PF03031.13 ETO35668.1 - 9.6e-15 54.5 0.8 2.6e-14 53.1 0.6 1.7 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 ETO35668.1 - 0.00021 21.5 0.0 0.00073 19.8 0.0 1.9 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase OmpH PF03938.9 ETO35668.1 - 5.4 6.9 19.5 12 5.7 13.5 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) s48_45 PF07422.8 ETO35669.1 - 0.031 14.3 1.0 0.05 13.7 0.7 1.5 1 1 0 1 1 1 0 Sexual stage antigen s48/45 domain WD40 PF00400.27 ETO35670.1 - 1.2e-17 62.9 7.2 1.8e-08 33.9 0.0 5.5 5 1 0 5 5 5 4 WD domain, G-beta repeat Herpes_DNAp_acc PF04929.7 ETO35670.1 - 3 6.7 15.4 0.16 10.9 6.6 1.7 2 0 0 2 2 2 0 Herpes DNA replication accessory factor Exo_endo_phos PF03372.18 ETO35671.1 - 3.6e-10 40.1 0.8 4.8e-10 39.8 0.6 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family EF-hand_7 PF13499.1 ETO35672.1 - 6.6e-06 26.1 2.5 0.065 13.3 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO35672.1 - 0.00075 19.1 1.9 0.26 11.2 0.3 3.9 3 1 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 ETO35672.1 - 0.0035 16.5 5.0 0.97 8.8 0.1 4.6 5 0 0 5 5 5 1 EF hand EF-hand_8 PF13833.1 ETO35672.1 - 0.36 10.4 3.8 12 5.6 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain pair Pex24p PF06398.6 ETO35673.1 - 0.06 12.1 0.5 0.066 12.0 0.4 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Peptidase_S49_N PF08496.5 ETO35674.1 - 1.3 8.7 5.6 3.9 7.2 3.9 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal GAPT PF11770.3 ETO35674.1 - 8 6.1 11.1 0.37 10.4 2.3 2.4 2 1 0 2 2 2 0 GRB2-binding adapter (GAPT) TFIIB PF00382.14 ETO35677.1 - 5.8e-18 64.4 1.2 2.8e-14 52.6 0.0 3.3 3 0 0 3 3 3 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 ETO35677.1 - 2.2e-06 26.8 8.3 1e-05 24.7 5.8 2.3 1 0 0 1 1 1 1 TFIIB zinc-binding BRF1 PF07741.8 ETO35677.1 - 0.0011 19.1 0.5 0.0011 19.1 0.4 3.4 2 1 0 2 2 2 1 Brf1-like TBP-binding domain Trypan_PARP PF05887.6 ETO35677.1 - 0.0064 16.3 5.2 0.014 15.2 3.6 1.6 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Lar_restr_allev PF14354.1 ETO35677.1 - 0.63 10.3 7.2 0.13 12.6 1.7 2.3 2 0 0 2 2 2 0 Restriction alleviation protein Lar CAP_GLY PF01302.20 ETO35678.1 - 7.2e-14 51.2 2.0 1.4e-13 50.2 1.0 1.7 2 0 0 2 2 2 1 CAP-Gly domain Mucin PF01456.12 ETO35678.1 - 0.52 10.0 44.0 0.12 12.0 18.7 3.2 3 0 0 3 3 3 0 Mucin-like glycoprotein YjcQ PF09639.5 ETO35679.1 - 0.014 15.4 0.9 0.076 13.1 0.1 2.6 2 0 0 2 2 2 0 YjcQ protein SET PF00856.23 ETO35679.1 - 1.4 9.2 5.3 0.87 9.8 1.4 2.4 2 1 0 2 2 2 0 SET domain PARP PF00644.15 ETO35680.1 - 7.8e-12 45.0 0.4 2.4e-10 40.1 0.1 2.2 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain DUF4117 PF13491.1 ETO35680.1 - 0.052 12.9 0.7 3.5 7.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4117) WD40 PF00400.27 ETO35681.1 - 6e-10 38.6 0.1 2.8e-09 36.4 0.0 2.0 2 0 0 2 2 2 1 WD domain, G-beta repeat Crust_neurohorm PF01147.12 ETO35681.1 - 0.065 12.5 2.3 0.15 11.4 1.6 1.6 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family MOR2-PAG1_C PF14225.1 ETO35682.1 - 2.7e-14 53.5 2.0 5.9e-14 52.4 0.0 2.5 2 1 1 3 3 3 1 Cell morphogenesis C-terminal Fis1_TPR_C PF14853.1 ETO35682.1 - 0.046 13.6 0.1 0.15 11.9 0.1 1.9 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat DUF3355 PF11835.3 ETO35684.1 - 0.044 13.5 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3355) SpoIISB_antitox PF14185.1 ETO35684.1 - 0.048 13.4 0.6 0.048 13.4 0.4 2.0 2 0 0 2 2 2 0 Antitoxin SpoIISB, type II toxin-antitoxin system DUF972 PF06156.8 ETO35685.1 - 0.0034 17.6 1.5 0.0043 17.3 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF972) CCDC144C PF14915.1 ETO35685.1 - 0.0065 15.4 1.1 0.0065 15.4 0.8 1.2 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region DUF837 PF05769.6 ETO35685.1 - 0.01 15.4 1.6 0.011 15.2 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF837) DUF2205 PF10224.4 ETO35685.1 - 0.029 13.9 0.6 0.034 13.7 0.4 1.3 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) DivIC PF04977.10 ETO35685.1 - 0.041 13.3 2.4 0.049 13.1 1.6 1.2 1 0 0 1 1 1 0 Septum formation initiator DUF3505 PF12013.3 ETO35685.1 - 0.043 14.0 0.7 0.049 13.8 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) DUF4047 PF13256.1 ETO35685.1 - 0.06 13.2 0.2 0.064 13.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) Atg14 PF10186.4 ETO35685.1 - 0.074 11.9 1.4 0.073 11.9 1.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF904 PF06005.7 ETO35685.1 - 0.16 12.3 4.4 0.24 11.7 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) TSC22 PF01166.13 ETO35685.1 - 0.18 11.7 3.7 0.25 11.3 2.2 1.6 1 1 0 1 1 1 0 TSC-22/dip/bun family Cep57_CLD_2 PF14197.1 ETO35685.1 - 0.19 11.7 2.5 0.24 11.3 1.8 1.4 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 Herpes_BLRF2 PF05812.7 ETO35685.1 - 0.24 11.2 3.0 0.36 10.6 2.1 1.3 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein DUF4041 PF13250.1 ETO35685.1 - 0.27 10.8 3.1 0.18 11.4 0.6 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4041) bZIP_1 PF00170.16 ETO35685.1 - 1.1 9.3 4.6 1.8 8.5 3.2 1.3 1 0 0 1 1 1 0 bZIP transcription factor SLA_LP_auto_ag PF05889.8 ETO35686.1 - 5.1e-05 21.9 0.3 0.023 13.1 0.0 2.2 1 1 1 2 2 2 2 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Pkr1 PF08636.5 ETO35687.1 - 5.3 7.1 7.7 0.36 10.9 1.7 1.7 2 0 0 2 2 2 0 ER protein Pkr1 TPR_6 PF13174.1 ETO35688.1 - 0.04 14.3 0.0 0.29 11.6 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat YfiO PF13525.1 ETO35688.1 - 0.06 12.7 0.2 2 7.8 0.1 2.1 2 0 0 2 2 2 0 Outer membrane lipoprotein Atx10homo_assoc PF09759.4 ETO35692.1 - 0.026 14.2 0.1 0.026 14.2 0.1 1.7 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Bestrophin PF01062.16 ETO35693.1 - 0.023 13.6 0.3 0.038 12.9 0.2 1.4 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel WD40 PF00400.27 ETO35694.1 - 1e-16 60.0 1.2 3.7e-05 23.4 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat SAM_1 PF00536.25 ETO35695.1 - 1.1e-07 31.8 0.1 1.8e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO35695.1 - 2e-07 30.7 0.1 3.6e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ste50p-SAM PF09235.5 ETO35695.1 - 0.0043 17.0 0.2 0.013 15.5 0.0 1.9 2 0 0 2 2 2 1 Ste50p, sterile alpha motif Peptidase_S10 PF00450.17 ETO35696.1 - 4.9e-29 101.7 0.2 6e-29 101.4 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase zf-C3HC4_2 PF13923.1 ETO35697.1 - 0.0005 20.0 1.4 0.0028 17.6 1.0 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Tet_JBP PF12851.2 ETO35697.1 - 0.062 12.5 3.0 0.058 12.6 1.1 1.6 1 1 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily NAD_binding_7 PF13241.1 ETO35697.1 - 0.4 10.9 1.9 0.91 9.8 0.3 2.1 1 1 1 2 2 2 0 Putative NAD(P)-binding Cys_knot PF00007.17 ETO35697.1 - 0.76 9.8 10.8 0.23 11.5 4.5 2.1 1 1 0 2 2 2 0 Cystine-knot domain DUF1644 PF07800.7 ETO35697.1 - 2.5 7.9 15.4 1.1 9.0 4.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1644) B56 PF01603.15 ETO35698.1 - 6.9e-109 364.1 9.2 7.8e-109 363.9 6.4 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Interferon PF00143.14 ETO35698.1 - 0.038 13.8 1.4 0.084 12.7 1.0 1.5 1 0 0 1 1 1 0 Interferon alpha/beta domain Tox-URI2 PF15653.1 ETO35699.1 - 6 7.1 11.1 8.4 6.6 1.4 3.2 3 0 0 3 3 3 0 URI fold toxin 2 OHA PF14418.1 ETO35700.1 - 0.012 15.1 0.2 6.5 6.3 0.0 2.4 2 0 0 2 2 2 0 OST-HTH Associated domain Lipase_GDSL PF00657.17 ETO35700.1 - 0.049 13.4 1.6 0.062 13.1 1.1 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Skp1_POZ PF03931.10 ETO35700.1 - 0.091 12.8 0.2 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain Pox_polyA_pol_C PF12629.2 ETO35700.1 - 0.44 10.2 6.5 1.4 8.5 0.6 2.2 2 0 0 2 2 2 0 Poxvirus poly(A) polymerase C-terminal domain CHAD PF05235.9 ETO35701.1 - 0.046 13.2 4.5 0.78 9.2 0.2 2.1 2 0 0 2 2 2 0 CHAD domain DUF2381 PF09544.5 ETO35701.1 - 0.075 12.1 1.3 0.15 11.1 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) Aminotran_1_2 PF00155.16 ETO35702.1 - 4e-49 167.4 0.0 4.8e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.16 ETO35702.1 - 1.4e-07 30.6 0.0 2.3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_5 PF00266.14 ETO35702.1 - 0.0046 15.7 0.0 0.0071 15.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V SHMT PF00464.14 ETO35702.1 - 0.0081 14.5 0.0 0.013 13.9 0.0 1.3 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 ETO35702.1 - 0.024 13.7 0.1 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Zot PF05707.7 ETO35702.1 - 0.09 12.2 0.1 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) SLA_LP_auto_ag PF05889.8 ETO35702.1 - 0.12 10.7 0.0 0.19 10.1 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Met_gamma_lyase PF06838.6 ETO35702.1 - 0.14 10.4 0.0 0.19 9.9 0.0 1.3 1 0 0 1 1 1 0 Methionine gamma-lyase WD40 PF00400.27 ETO35703.1 - 2e-66 217.6 24.5 2.2e-12 46.3 0.0 6.9 6 1 1 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO35703.1 - 5.2e-05 21.5 5.8 1.2 7.1 0.0 4.8 1 1 3 4 4 4 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETO35703.1 - 0.00065 19.2 0.2 0.012 15.1 0.1 2.2 1 1 0 1 1 1 1 PQQ-like domain Nucleoporin_N PF08801.6 ETO35703.1 - 0.015 14.0 6.3 0.27 9.9 0.2 3.4 1 1 2 4 4 4 0 Nup133 N terminal like PD40 PF07676.7 ETO35703.1 - 0.033 13.8 1.9 2 8.1 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO35703.1 - 0.048 11.9 0.4 3.5 5.8 0.0 2.7 2 1 1 3 3 3 0 Cytochrome D1 heme domain WD40 PF00400.27 ETO35704.1 - 3.2e-58 191.6 24.8 7.4e-12 44.6 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO35704.1 - 2.5e-07 29.2 7.6 0.41 8.7 0.2 5.0 1 1 3 5 5 5 5 Nucleoporin Nup120/160 DUF851 PF05867.6 ETO35704.1 - 0.01 15.0 0.7 4.4 6.4 0.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF851) Destabilase PF05497.7 ETO35705.1 - 8.2e-10 38.8 0.3 1.1e-09 38.4 0.2 1.2 1 0 0 1 1 1 1 Destabilase Kei1 PF08552.6 ETO35706.1 - 3.4 7.3 5.7 0.62 9.6 1.1 2.0 2 1 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Secretin_N_2 PF07655.8 ETO35708.1 - 0.15 12.4 7.5 0.039 14.3 2.1 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain Sporozoite_P67 PF05642.6 ETO35708.1 - 0.47 8.2 4.4 0.42 8.4 3.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TFIIA PF03153.8 ETO35708.1 - 0.87 9.4 13.0 1.2 9.0 9.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FLO_LFY PF01698.11 ETO35708.1 - 2.1 7.0 5.4 2.9 6.6 3.7 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein FAM176 PF14851.1 ETO35708.1 - 2.8 7.6 7.4 0.88 9.2 1.9 2.0 2 0 0 2 2 2 0 FAM176 family Nop14 PF04147.7 ETO35708.1 - 4.6 5.0 10.1 5.8 4.7 7.0 1.2 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.6 ETO35708.1 - 6.4 6.5 11.6 1 9.1 4.6 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal Sigma70_ner PF04546.8 ETO35708.1 - 6.6 6.2 10.3 1.6 8.3 3.8 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region tRNA_U5-meth_tr PF05958.6 ETO35709.1 - 0.069 11.8 0.0 0.095 11.3 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase TAFH PF07531.9 ETO35710.1 - 0.015 14.9 0.1 0.12 12.0 0.0 2.2 2 0 0 2 2 2 0 NHR1 homology to TAF RGS PF00615.14 ETO35711.1 - 0.00019 21.4 0.2 0.002 18.1 0.1 2.2 1 1 0 1 1 1 1 Regulator of G protein signaling domain NUP50 PF08911.6 ETO35712.1 - 0.12 12.7 0.1 0.16 12.3 0.1 1.2 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) Snf7 PF03357.16 ETO35712.1 - 0.46 9.8 3.4 0.54 9.6 2.4 1.1 1 0 0 1 1 1 0 Snf7 DUF1539 PF07560.6 ETO35714.1 - 0.008 16.0 0.1 0.008 16.0 0.1 2.7 3 0 0 3 3 3 1 Domain of Unknown Function (DUF1539) WD40 PF00400.27 ETO35715.1 - 2e-39 132.0 0.6 1.1e-10 40.9 0.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO35715.1 - 2.2e-06 27.5 0.5 0.008 15.8 0.0 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO35715.1 - 1.2e-05 23.6 5.7 0.062 11.4 0.0 4.3 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO35715.1 - 7.2e-05 21.7 6.3 0.1 11.3 0.3 3.5 1 1 3 4 4 4 2 Nup133 N terminal like BBS2_Mid PF14783.1 ETO35715.1 - 9.9e-05 22.0 0.6 0.036 13.8 0.1 2.6 2 1 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Cytochrom_D1 PF02239.11 ETO35715.1 - 0.00013 20.4 0.2 0.015 13.6 0.1 2.3 1 1 2 3 3 3 2 Cytochrome D1 heme domain PD40 PF07676.7 ETO35715.1 - 0.00013 21.5 0.1 9.7 5.9 0.0 4.2 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Hira PF07569.6 ETO35715.1 - 0.0081 15.3 0.8 9.7 5.3 0.0 3.7 1 1 3 4 4 4 1 TUP1-like enhancer of split DUF2441 PF10386.4 ETO35715.1 - 0.05 13.6 0.1 0.72 9.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2441) CYTL1 PF15153.1 ETO35716.1 - 0.038 13.6 0.1 0.066 12.9 0.1 1.4 1 0 0 1 1 1 0 Cytokine-like protein 1 DUF3301 PF11743.3 ETO35718.1 - 0.1 12.1 0.7 0.14 11.6 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3301) Prenyltransf PF01255.14 ETO35720.1 - 0.076 12.1 0.6 0.12 11.4 0.3 1.4 1 1 0 1 1 1 0 Putative undecaprenyl diphosphate synthase Kelch_6 PF13964.1 ETO35721.1 - 1.7e-06 27.9 0.8 0.086 13.0 0.1 3.1 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 ETO35721.1 - 0.00013 21.6 0.2 0.098 12.4 0.0 3.5 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO35721.1 - 0.003 17.2 0.8 0.81 9.5 0.0 2.7 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.20 ETO35721.1 - 0.0033 16.9 3.2 1.5 8.4 0.1 3.2 3 0 0 3 3 3 2 Kelch motif RTX_C PF08339.5 ETO35721.1 - 0.064 12.9 0.1 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 RTX C-terminal domain Ribosomal_S8e PF01201.17 ETO35722.1 - 0.062 13.4 5.6 0.11 12.6 3.8 1.4 1 0 0 1 1 1 0 Ribosomal protein S8e Dala_Dala_lig_N PF01820.16 ETO35722.1 - 0.2 11.9 1.1 0.52 10.6 0.8 1.8 1 1 0 1 1 1 0 D-ala D-ala ligase N-terminus NACHT PF05729.7 ETO35723.1 - 1.3e-05 24.9 0.0 2.8e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 NACHT domain WD40 PF00400.27 ETO35724.1 - 5.4e-31 105.3 9.1 4.5e-11 42.1 0.0 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO35724.1 - 1.5e-10 39.8 1.0 1.7e-05 23.1 0.1 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 WD40 PF00400.27 ETO35725.1 - 9.8e-48 158.4 20.2 3.3e-12 45.7 0.1 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO35725.1 - 1.8e-07 29.6 2.8 0.019 13.0 0.2 4.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 WD40 PF00400.27 ETO35726.1 - 3.5e-25 86.9 5.3 7.6e-09 35.1 0.4 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO35726.1 - 1.7e-05 23.2 0.6 0.011 13.9 0.2 2.5 1 1 1 2 2 2 2 Nucleoporin Nup120/160 RNA_pol_L_2 PF13656.1 ETO35726.1 - 0.016 14.6 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain BBS2_Mid PF14783.1 ETO35726.1 - 0.039 13.7 0.5 0.31 10.8 0.1 2.2 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.27 ETO35727.1 - 6.9e-23 79.6 11.5 6.6e-11 41.6 0.0 4.6 4 1 0 4 4 4 3 WD domain, G-beta repeat eIF2A PF08662.6 ETO35727.1 - 0.0013 18.4 0.4 0.49 10.0 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO35727.1 - 0.0055 14.9 0.1 0.084 10.9 0.0 2.1 1 1 0 1 1 1 1 Nucleoporin Nup120/160 DUF1660 PF07874.6 ETO35728.1 - 0.051 13.8 0.5 0.11 12.8 0.4 1.6 1 0 0 1 1 1 0 Prophage protein (DUF1660) Cdd1 PF11731.3 ETO35728.1 - 1.3 9.0 4.9 29 4.6 0.9 2.9 2 1 0 2 2 2 0 Pathogenicity locus Neur_chan_memb PF02932.11 ETO35729.1 - 2.4 7.9 7.2 5.5 6.7 0.4 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Vfa1 PF08432.5 ETO35729.1 - 4.5 7.2 25.4 0.33 10.9 9.9 2.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 UQ_con PF00179.21 ETO35730.1 - 2.7e-40 137.0 0.1 2.8e-37 127.2 0.0 2.9 1 1 1 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 ETO35730.1 - 0.00016 21.3 0.0 0.00026 20.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 ETO35730.1 - 0.016 15.0 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 RWD domain Pyr_redox PF00070.22 ETO35731.1 - 3.2e-07 30.6 0.0 6.4e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETO35731.1 - 8.9e-05 22.4 0.0 0.00025 20.9 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rifin_STEVOR PF02009.11 ETO35731.1 - 7.8 6.0 8.2 16 5.0 5.7 1.4 1 0 0 1 1 1 0 Rifin/stevor family Plug_translocon PF10559.4 ETO35732.1 - 4.3e-10 38.9 0.0 2.4e-09 36.5 0.0 2.3 3 0 0 3 3 3 1 Plug domain of Sec61p Med30 PF11315.3 ETO35733.1 - 0.1 12.7 0.9 15 5.6 0.1 2.7 1 1 2 3 3 3 0 Mediator complex subunit 30 WD40 PF00400.27 ETO35735.1 - 5.5e-15 54.5 7.6 3e-11 42.7 0.2 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO35735.1 - 0.0074 14.4 0.3 0.72 7.9 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Gtr1_RagA PF04670.7 ETO35736.1 - 3e-41 141.0 5.9 3.8e-41 140.7 1.7 2.4 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region LSM14 PF12701.2 ETO35736.1 - 0.0019 18.0 0.1 0.0049 16.6 0.1 1.7 1 0 0 1 1 1 1 Scd6-like Sm domain SRPRB PF09439.5 ETO35736.1 - 0.015 14.5 0.0 0.037 13.2 0.0 1.7 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Miro PF08477.8 ETO35736.1 - 0.05 14.1 0.0 0.2 12.1 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein HEAT PF02985.17 ETO35737.1 - 1.1e-09 37.5 0.1 0.0016 18.3 0.0 2.5 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.1 ETO35737.1 - 6.2e-05 23.2 0.1 0.00014 22.0 0.1 1.6 1 1 0 1 1 1 1 HEAT repeats Adaptin_N PF01602.15 ETO35737.1 - 0.0074 14.6 0.2 0.01 14.2 0.2 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 ETO35737.1 - 0.02 14.7 0.0 0.028 14.2 0.0 1.3 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 SMC_N PF02463.14 ETO35738.1 - 6.6e-14 51.6 1.6 1.1e-13 50.9 1.1 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 ETO35738.1 - 0.00036 20.3 0.1 0.0014 18.5 0.0 1.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.22 ETO35738.1 - 0.13 12.6 1.4 0.22 11.7 0.9 1.5 1 1 0 1 1 1 0 ABC transporter DUF4302 PF14135.1 ETO35738.1 - 0.29 10.4 3.9 0.4 10.0 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4302) ZapA PF05164.8 ETO35738.1 - 0.71 9.8 3.4 1.1 9.3 0.2 2.4 2 1 1 3 3 3 0 Cell division protein ZapA BRCT PF00533.21 ETO35739.1 - 0.035 14.2 0.7 0.078 13.1 0.5 1.6 1 1 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DUF2721 PF11026.3 ETO35740.1 - 0.022 14.3 0.7 0.031 13.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Adeno_E3 PF06040.6 ETO35740.1 - 1 9.3 10.3 0.059 13.3 3.6 1.6 1 1 1 2 2 2 0 Adenovirus E3 protein WD40 PF00400.27 ETO35741.1 - 1.8e-16 59.2 4.9 5e-06 26.2 0.0 4.8 5 1 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO35741.1 - 0.012 13.8 0.1 0.77 7.8 0.0 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Phosphorylase PF00343.15 ETO35741.1 - 0.082 10.7 0.1 4 5.1 0.0 2.0 1 1 1 2 2 2 0 Carbohydrate phosphorylase Nucleoporin_N PF08801.6 ETO35741.1 - 0.16 10.6 0.5 0.6 8.7 0.4 1.7 1 1 0 1 1 1 0 Nup133 N terminal like DUF572 PF04502.8 ETO35744.1 - 1.5e-44 152.5 39.3 4.6e-44 150.9 27.3 1.7 1 1 0 1 1 1 1 Family of unknown function (DUF572) RNA_pol_N PF01194.12 ETO35744.1 - 0.016 15.2 0.3 0.82 9.7 0.0 2.9 2 0 0 2 2 2 0 RNA polymerases N / 8 kDa subunit RNA_POL_M_15KD PF02150.11 ETO35744.1 - 0.97 9.1 4.7 2.4 7.9 0.4 2.5 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit TLP-20 PF06088.6 ETO35745.1 - 0.91 9.1 3.9 1.1 8.9 2.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) HEAT PF02985.17 ETO35746.1 - 3.8e-05 23.4 0.6 0.33 11.1 0.0 4.4 4 1 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.1 ETO35746.1 - 7.2e-05 22.9 0.0 0.059 13.6 0.0 3.0 1 1 1 3 3 3 1 HEAT repeats HEAT_EZ PF13513.1 ETO35746.1 - 0.00052 20.4 0.0 0.025 15.0 0.0 3.1 2 2 2 4 4 4 1 HEAT-like repeat Cnd1 PF12717.2 ETO35746.1 - 0.0021 17.9 6.6 0.041 13.7 0.1 2.4 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 DUF3554 PF12074.3 ETO35746.1 - 0.01 15.2 0.5 0.17 11.2 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3554) UPF0147 PF03685.8 ETO35746.1 - 0.012 15.4 0.9 0.026 14.3 0.6 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) Herpes_UL55 PF04537.7 ETO35746.1 - 0.026 13.9 0.4 0.055 12.8 0.3 1.6 1 0 0 1 1 1 0 Herpesvirus UL55 protein HrcA PF01628.16 ETO35746.1 - 0.033 13.7 0.4 2.1 7.9 0.0 2.1 2 0 0 2 2 2 0 HrcA protein C terminal domain CLASP_N PF12348.3 ETO35746.1 - 0.039 13.3 3.0 0.26 10.5 0.8 2.8 2 1 0 2 2 2 0 CLASP N terminal MMS19_C PF12460.3 ETO35746.1 - 0.057 12.1 7.8 0.14 10.8 1.1 2.1 1 1 1 2 2 2 0 RNAPII transcription regulator C-terminal IPK PF03770.11 ETO35746.1 - 0.062 12.9 1.3 0.14 11.8 0.6 1.7 1 1 0 1 1 1 0 Inositol polyphosphate kinase DSHCT PF08148.7 ETO35746.1 - 0.083 12.1 0.3 0.41 9.8 0.0 1.9 2 0 0 2 2 2 0 DSHCT (NUC185) domain FPL PF09758.4 ETO35746.1 - 0.12 12.1 5.4 1.9 8.2 0.3 3.3 2 2 2 4 4 4 0 Uncharacterised conserved protein MIase PF02426.11 ETO35747.1 - 0.066 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Muconolactone delta-isomerase DUF2919 PF11143.3 ETO35747.1 - 0.92 9.3 5.6 0.21 11.4 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2919) Calpain_III PF01067.17 ETO35748.1 - 9.4e-18 64.2 1.4 2.7e-17 62.7 1.0 1.6 1 1 0 1 1 1 1 Calpain large subunit, domain III DUF4087 PF13316.1 ETO35748.1 - 0.11 12.6 0.3 0.25 11.5 0.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4087) WD40 PF00400.27 ETO35749.1 - 3e-60 198.0 15.2 1.8e-10 40.2 0.0 8.1 7 1 0 7 7 7 7 WD domain, G-beta repeat PQQ_2 PF13360.1 ETO35749.1 - 2.2e-07 30.5 0.2 1.8e-06 27.6 0.1 2.3 1 1 1 2 2 2 1 PQQ-like domain Nup160 PF11715.3 ETO35749.1 - 0.00023 19.4 5.1 1.1 7.3 0.2 4.0 1 1 1 3 3 3 3 Nucleoporin Nup120/160 PD40 PF07676.7 ETO35749.1 - 0.00034 20.2 4.4 7.5 6.3 0.1 5.2 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat DUF1652 PF07865.6 ETO35749.1 - 0.0086 15.6 0.0 4 7.1 0.0 4.2 3 1 1 4 4 4 1 Protein of unknown function (DUF1652) Aminotran_1_2 PF00155.16 ETO35750.1 - 2.4e-54 184.6 0.0 1.7e-41 142.3 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Beta_elim_lyase PF01212.16 ETO35750.1 - 1.9e-06 27.2 0.0 3.3e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 ETO35750.1 - 8.6e-06 24.2 0.0 1.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 ETO35750.1 - 3.3e-05 23.1 0.0 0.00019 20.6 0.0 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 ETO35750.1 - 0.01 14.6 0.0 0.04 12.6 0.0 1.8 2 0 0 2 2 2 0 Aminotransferase class-V WD40 PF00400.27 ETO35751.1 - 5.4e-16 57.7 10.0 2.1e-08 33.6 1.3 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO35751.1 - 0.0028 15.8 1.4 0.26 9.3 0.1 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 WD40 PF00400.27 ETO35752.1 - 9.4e-20 69.7 10.6 1.6e-11 43.6 0.1 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO35752.1 - 1.6e-05 23.2 0.7 0.03 12.4 0.0 2.7 1 1 2 3 3 3 3 Nucleoporin Nup120/160 LMBR1 PF04791.11 ETO35753.1 - 0.64 8.5 5.3 0.9 8.0 3.7 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1510 PF07423.6 ETO35753.1 - 8.2 5.7 30.7 0.43 9.9 11.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) WD40 PF00400.27 ETO35754.1 - 3.1e-16 58.5 2.1 6.1e-11 41.7 0.2 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat PPR_2 PF13041.1 ETO35754.1 - 9.5e-12 44.7 6.0 3.7e-05 23.6 0.1 4.9 2 1 3 5 5 5 5 PPR repeat family PPR_3 PF13812.1 ETO35754.1 - 1.8e-09 37.0 0.0 0.049 13.9 0.0 5.0 4 0 0 4 4 4 3 Pentatricopeptide repeat domain PPR PF01535.15 ETO35754.1 - 2.2e-09 36.6 8.3 0.088 12.8 0.1 5.4 6 0 0 6 6 6 3 PPR repeat PPR_1 PF12854.2 ETO35754.1 - 8.7e-05 21.9 5.3 0.41 10.1 0.0 4.0 4 0 0 4 4 4 2 PPR repeat Nup160 PF11715.3 ETO35754.1 - 0.00074 17.7 0.3 1.6 6.7 0.0 3.1 2 1 1 3 3 3 2 Nucleoporin Nup120/160 WD40 PF00400.27 ETO35755.1 - 9.1e-62 202.9 28.3 1.4e-10 40.5 1.1 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO35755.1 - 1.3e-07 30.1 10.6 0.0041 15.3 0.3 5.2 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO35755.1 - 0.0063 15.3 14.5 0.59 8.8 0.2 4.1 1 1 1 3 3 3 2 Nup133 N terminal like NAD_Gly3P_dh_N PF01210.18 ETO35755.1 - 0.0064 16.2 0.0 1.2 8.8 0.0 3.3 4 0 0 4 4 4 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ole-e-6 PF09253.5 ETO35755.1 - 0.29 10.8 3.9 0.41 10.3 0.1 2.6 2 0 0 2 2 2 0 Pollen allergen ole e 6 DUF2559 PF10832.3 ETO35755.1 - 1.2 9.0 9.3 0.49 10.2 0.2 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2559) WD40 PF00400.27 ETO35757.1 - 1.7e-31 106.9 16.2 5.6e-11 41.8 0.4 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO35757.1 - 1.5e-07 29.9 0.2 0.0034 15.6 0.0 3.7 2 1 2 4 4 4 3 Nucleoporin Nup120/160 GTP_EFTU PF00009.22 ETO35757.1 - 0.0035 16.8 0.0 0.0062 16.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Nucleoporin_N PF08801.6 ETO35757.1 - 0.0066 15.2 6.8 3.6 6.2 3.5 4.4 1 1 2 3 3 3 1 Nup133 N terminal like AphA_like PF14557.1 ETO35757.1 - 0.053 13.0 0.0 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator SusD-like_3 PF14322.1 ETO35758.1 - 0.92 9.5 4.5 1.6 8.7 3.1 1.4 1 1 0 1 1 1 0 Starch-binding associating with outer membrane Ribonuc_L-PSP PF01042.16 ETO35759.1 - 2.2e-05 24.1 0.0 4.8e-05 23.0 0.0 1.5 2 0 0 2 2 2 1 Endoribonuclease L-PSP IBR PF01485.16 ETO35759.1 - 0.27 11.1 2.8 0.87 9.5 1.9 1.9 1 1 0 1 1 1 0 IBR domain Pox_J1 PF03338.10 ETO35760.1 - 0.012 15.2 0.4 1.5 8.4 0.1 2.6 2 0 0 2 2 2 0 Poxvirus J1 protein Mucin PF01456.12 ETO35760.1 - 0.023 14.4 51.4 0.056 13.2 35.6 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein EII-Sor PF03609.9 ETO35760.1 - 0.13 11.4 10.5 0.25 10.5 7.3 1.5 1 0 0 1 1 1 0 PTS system sorbose-specific iic component PAP1 PF08601.5 ETO35760.1 - 0.6 9.7 8.2 0.97 9.0 5.7 1.3 1 1 0 1 1 1 0 Transcription factor PAP1 Rifin_STEVOR PF02009.11 ETO35760.1 - 4.5 6.8 11.0 7.2 6.1 7.6 1.3 1 0 0 1 1 1 0 Rifin/stevor family DUF2057 PF09829.4 ETO35760.1 - 6.7 6.3 16.9 16 5.0 11.7 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) MSP1_C PF07462.6 ETO35760.1 - 9.8 4.4 14.5 16 3.7 10.0 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus WD40 PF00400.27 ETO35761.1 - 5.3e-29 99.0 17.6 4.3e-10 39.0 0.0 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO35761.1 - 6.7e-07 27.8 1.9 0.004 15.3 0.3 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 ubiquitin PF00240.18 ETO35763.1 - 6.7e-12 44.6 2.0 6.9e-12 44.5 0.0 2.1 2 1 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 ETO35763.1 - 6.6e-09 35.3 0.3 1.1e-07 31.3 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Nuc_sug_transp PF04142.10 ETO35764.1 - 5.5e-25 87.8 2.3 6.3e-25 87.6 1.6 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 ETO35764.1 - 1.7e-06 28.0 8.9 1.1e-05 25.4 1.3 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 ETO35764.1 - 3.7e-05 23.4 1.4 3.7e-05 23.4 1.0 1.9 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 ETO35764.1 - 0.00017 20.6 1.3 0.00017 20.6 0.9 1.7 2 0 0 2 2 2 1 UAA transporter family EmrE PF13536.1 ETO35764.1 - 0.0016 18.5 1.6 0.0016 18.5 1.1 1.9 2 0 0 2 2 2 1 Multidrug resistance efflux transporter GET2 PF08690.5 ETO35764.1 - 0.035 13.3 0.4 0.059 12.6 0.3 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 zf-DHHC PF01529.15 ETO35764.1 - 0.67 9.3 11.1 1 8.6 7.7 1.5 1 1 0 1 1 1 0 DHHC palmitoyltransferase TMCO5 PF14992.1 ETO35764.1 - 1.7 7.7 5.6 0.084 11.9 0.4 1.4 2 0 0 2 2 2 0 TMCO5 family Nuc_sug_transp PF04142.10 ETO35765.1 - 5.4e-23 81.3 11.2 7.4e-23 80.9 7.7 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter UPF0060 PF02694.10 ETO35765.1 - 0.05 13.6 4.5 0.7 9.9 1.1 2.4 1 1 1 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family CENP-F_C_Rb_bdg PF10490.4 ETO35766.1 - 0.0018 17.5 0.0 0.0038 16.4 0.0 1.5 1 0 0 1 1 1 1 Rb-binding domain of kinetochore protein Cenp-F/LEK1 FANCL_C PF11793.3 ETO35766.1 - 0.038 13.9 7.2 0.058 13.3 0.1 3.4 4 0 0 4 4 4 0 FANCL C-terminal domain PB1 PF00564.19 ETO35767.1 - 0.011 15.3 0.3 0.016 14.8 0.2 1.3 1 0 0 1 1 1 0 PB1 domain UN_NPL4 PF11543.3 ETO35767.1 - 0.013 15.7 0.0 0.02 15.1 0.0 1.3 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 DUF1031 PF06275.6 ETO35767.1 - 0.04 13.9 0.6 0.064 13.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1031) DSPc PF00782.15 ETO35768.1 - 3.8e-23 81.5 0.7 1.9e-20 72.7 0.1 2.5 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 ETO35768.1 - 0.00015 21.1 0.6 0.0003 20.1 0.4 1.6 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Poty_coat PF00767.13 ETO35768.1 - 0.2 10.8 1.6 3 7.0 0.1 2.3 3 0 0 3 3 3 0 Potyvirus coat protein Pkinase PF00069.20 ETO35769.1 - 1.3e-23 83.5 1.9 1e-16 60.8 0.6 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO35769.1 - 1.9e-15 56.6 0.4 8.1e-14 51.3 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 ETO35769.1 - 0.00031 19.8 1.3 0.00037 19.6 0.1 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family TerB-C PF15615.1 ETO35770.1 - 2.3 8.4 7.8 0.57 10.4 2.1 2.2 2 0 0 2 2 2 0 TerB-C domain Ferric_reduct PF01794.14 ETO35771.1 - 1.1e-06 28.7 6.7 4.9e-06 26.6 4.6 2.2 1 1 0 1 1 1 1 Ferric reductase like transmembrane component DUF373 PF04123.8 ETO35771.1 - 0.36 9.8 5.3 6.4 5.6 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF373) 2TM PF13239.1 ETO35771.1 - 1.5 8.9 9.7 1.8 8.7 0.0 3.6 3 0 0 3 3 3 0 2TM domain DUF972 PF06156.8 ETO35772.1 - 0.0024 18.2 14.1 0.0024 18.2 9.8 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF972) Mnd1 PF03962.10 ETO35772.1 - 0.01 15.5 0.2 0.01 15.5 0.1 2.4 1 1 1 2 2 2 0 Mnd1 family Macoilin PF09726.4 ETO35772.1 - 0.028 12.7 23.0 0.03 12.6 15.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Tropomyosin PF00261.15 ETO35772.1 - 0.091 11.8 26.5 0.12 11.4 4.6 2.3 1 1 1 2 2 2 0 Tropomyosin DivIC PF04977.10 ETO35772.1 - 0.097 12.1 0.2 0.097 12.1 0.2 5.0 2 1 1 3 3 2 0 Septum formation initiator Exonuc_VII_L PF02601.10 ETO35772.1 - 0.44 9.6 20.7 0.67 9.0 14.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF607 PF04678.8 ETO35772.1 - 0.47 10.3 18.5 0.18 11.6 4.9 2.3 1 1 1 2 2 2 0 Protein of unknown function, DUF607 DUF3735 PF12537.3 ETO35772.1 - 0.55 10.3 17.2 0.63 10.1 0.9 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3735) CENP-F_leu_zip PF10473.4 ETO35772.1 - 0.81 9.5 40.9 10 6.0 17.1 3.1 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MutS_IV PF05190.13 ETO35772.1 - 0.97 9.6 14.5 0.94 9.6 0.9 3.3 1 1 2 3 3 3 0 MutS family domain IV Med15 PF09606.5 ETO35772.1 - 1.1 7.4 35.4 1.2 7.2 24.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pox_A_type_inc PF04508.7 ETO35772.1 - 1.8 8.5 10.0 13 5.9 0.1 4.3 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat TMF_TATA_bd PF12325.3 ETO35772.1 - 3.1 7.5 37.4 0.057 13.1 5.7 4.0 2 1 2 4 4 3 0 TATA element modulatory factor 1 TATA binding Filo_VP35 PF02097.10 ETO35772.1 - 3.3 6.8 9.5 2.4 7.2 5.3 1.6 1 1 1 2 2 2 0 Filoviridae VP35 UPF0184 PF03670.8 ETO35772.1 - 3.4 7.9 6.5 0.65 10.2 0.7 2.4 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0184) Reo_sigmaC PF04582.7 ETO35772.1 - 3.7 6.6 5.2 5.5 6.0 0.8 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein HOOK PF05622.7 ETO35772.1 - 4.1 5.0 40.0 1.8 6.2 25.2 2.0 2 1 0 2 2 2 0 HOOK protein FUSC PF04632.7 ETO35772.1 - 7.3 4.8 10.1 9.1 4.5 7.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family GIY-YIG PF01541.19 ETO35773.1 - 0.066 13.5 2.4 1.4 9.3 0.1 2.7 2 0 0 2 2 2 0 GIY-YIG catalytic domain WD40 PF00400.27 ETO35774.1 - 2.9e-05 23.7 6.4 0.0013 18.5 0.7 2.6 2 1 0 2 2 2 2 WD domain, G-beta repeat DUF1340 PF07067.6 ETO35774.1 - 0.0015 17.7 0.3 0.0021 17.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1340) DEP PF00610.16 ETO35775.1 - 8.9e-15 54.1 0.0 1.6e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Adenine_glyco PF03352.8 ETO35775.1 - 0.0064 16.0 0.4 0.38 10.2 0.1 2.2 2 0 0 2 2 2 2 Methyladenine glycosylase Vpu PF00558.14 ETO35775.1 - 0.008 15.7 0.2 0.015 14.8 0.2 1.5 1 0 0 1 1 1 1 Vpu protein zf-DHHC PF01529.15 ETO35775.1 - 0.97 8.8 4.3 1.6 8.1 3.0 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase C2 PF00168.25 ETO35777.1 - 1.7e-12 47.0 0.8 3.9e-12 45.8 0.3 1.8 2 0 0 2 2 2 1 C2 domain PALP PF00291.20 ETO35778.1 - 3.7e-08 32.9 0.0 8.4e-08 31.7 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PALP PF00291.20 ETO35779.1 - 3.1e-13 49.6 0.0 4.4e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ald_Xan_dh_C PF01315.17 ETO35780.1 - 0.14 12.2 0.2 0.76 9.8 0.0 2.0 1 1 1 2 2 2 0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain WD40 PF00400.27 ETO35784.1 - 1.8e-16 59.3 2.8 2.9e-10 39.6 0.0 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 ETO35784.1 - 0.00057 19.6 0.8 0.28 10.9 0.3 2.6 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 ETO35784.1 - 0.015 14.0 0.3 1.5 7.4 0.0 2.0 1 1 1 2 2 2 0 Nup133 N terminal like Nup160 PF11715.3 ETO35784.1 - 0.017 13.3 0.3 1.7 6.7 0.1 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 DUF2578 PF10843.3 ETO35784.1 - 0.11 12.2 0.1 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2578) SprB PF13573.1 ETO35784.1 - 0.14 11.7 9.1 1.3 8.7 0.2 3.2 3 0 0 3 3 3 0 SprB repeat Adeno_VII PF03228.9 ETO35785.1 - 0.012 16.2 0.1 0.021 15.4 0.1 1.3 1 0 0 1 1 1 0 Adenoviral core protein VII YkyB PF14177.1 ETO35785.1 - 0.25 11.4 5.5 0.48 10.5 0.3 2.8 2 1 1 3 3 3 0 YkyB-like protein Rsc14 PF08586.5 ETO35785.1 - 0.81 10.2 4.3 18 5.8 0.2 2.7 3 0 0 3 3 3 0 RSC complex, Rsc14/Ldb7 subunit Siah-Interact_N PF09032.6 ETO35785.1 - 6 7.0 10.6 18 5.4 3.4 2.7 2 0 0 2 2 2 0 Siah interacting protein, N terminal zf-C4H2 PF10146.4 ETO35785.1 - 6.1 6.7 9.8 34 4.3 6.8 2.1 1 1 0 1 1 1 0 Zinc finger-containing protein IF4E PF01652.13 ETO35786.1 - 6.4e-37 126.6 3.6 9.3e-37 126.0 2.5 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF3450 PF11932.3 ETO35787.1 - 0.04 13.1 11.7 0.022 14.0 6.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) IncA PF04156.9 ETO35787.1 - 3 7.4 12.4 5 6.6 8.6 1.3 1 0 0 1 1 1 0 IncA protein BRE1 PF08647.6 ETO35787.1 - 9.9 6.2 13.0 13 5.8 6.5 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase NOP5NT PF08156.8 ETO35788.1 - 0.055 13.6 1.6 8 6.6 0.0 2.1 2 0 0 2 2 2 0 NOP5NT (NUC127) domain Toprim PF01751.17 ETO35788.1 - 1.4 8.9 5.7 8 6.5 3.9 1.9 1 1 0 1 1 1 0 Toprim domain TMEM247 PF15444.1 ETO35790.1 - 6.1 6.6 11.5 4 7.1 0.0 2.5 2 1 0 2 2 2 0 Transmembrane protein 247 Raffinose_syn PF05691.7 ETO35791.1 - 0.0014 16.2 0.3 0.0022 15.6 0.2 1.2 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 ACP53EA PF06313.6 ETO35791.1 - 0.029 14.3 0.4 0.1 12.5 0.2 1.9 2 0 0 2 2 2 0 Drosophila ACP53EA protein T2SM PF04612.7 ETO35791.1 - 0.1 12.3 3.7 0.26 11.0 0.8 2.6 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M CENP-F_leu_zip PF10473.4 ETO35791.1 - 0.12 12.2 13.2 0.43 10.4 0.4 3.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BRE1 PF08647.6 ETO35791.1 - 0.14 12.0 14.1 0.049 13.6 0.9 2.9 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase MerR-DNA-bind PF09278.6 ETO35791.1 - 0.23 11.8 5.7 10 6.6 0.0 3.5 2 1 1 3 3 3 0 MerR, DNA binding DUF3496 PF12001.3 ETO35791.1 - 0.54 10.5 4.4 1.3 9.3 1.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) IncA PF04156.9 ETO35791.1 - 0.59 9.7 17.6 6.5 6.2 12.1 2.6 1 1 0 1 1 1 0 IncA protein DUF904 PF06005.7 ETO35791.1 - 2.4 8.5 9.7 2.1 8.7 1.9 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF2726 PF10881.3 ETO35793.1 - 0.085 12.4 0.1 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) EphA2_TM PF14575.1 ETO35794.1 - 0.00074 19.8 0.1 0.0063 16.8 0.0 2.2 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.6 ETO35794.1 - 0.0045 16.6 4.1 1 8.9 2.9 2.1 1 1 0 1 1 1 1 Protocadherin DUF4133 PF13571.1 ETO35794.1 - 0.014 15.5 0.3 0.022 14.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4133) Mid2 PF04478.7 ETO35794.1 - 0.055 12.8 0.1 0.055 12.8 0.1 2.0 3 0 0 3 3 3 0 Mid2 like cell wall stress sensor TMEM154 PF15102.1 ETO35794.1 - 0.12 12.0 0.2 0.12 12.0 0.1 3.2 1 1 2 3 3 3 0 TMEM154 protein family Orthoreo_P10 PF07204.6 ETO35794.1 - 0.15 11.8 0.1 0.24 11.1 0.1 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 DUF912 PF06024.7 ETO35794.1 - 0.73 9.9 0.1 0.73 9.9 0.0 2.9 2 1 2 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) MRAP PF15183.1 ETO35795.1 - 9.4 5.9 7.5 2.1 7.9 1.6 2.5 2 1 0 2 2 2 0 Melanocortin-2 receptor accessory protein family VIT1 PF01988.14 ETO35796.1 - 0.11 12.0 2.2 0.11 12.0 0.3 2.0 2 0 0 2 2 2 0 VIT family HsbA PF12296.3 ETO35797.1 - 0.061 13.1 0.0 1.1 9.1 0.0 2.0 2 0 0 2 2 2 0 Hydrophobic surface binding protein A PIN PF01850.16 ETO35797.1 - 0.1 12.9 0.2 0.12 12.6 0.1 1.1 1 0 0 1 1 1 0 PIN domain Ecotin PF03974.8 ETO35798.1 - 0.1 12.3 0.3 0.18 11.5 0.2 1.4 1 0 0 1 1 1 0 Ecotin UDPGT PF00201.13 ETO35798.1 - 0.16 10.4 0.9 0.19 10.2 0.6 1.0 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase CXCL17 PF15211.1 ETO35798.1 - 9.6 6.6 9.6 0.27 11.6 1.0 2.2 1 1 1 2 2 2 0 VEGF co-regulated chemokine 1 Receptor_2B4 PF11465.3 ETO35799.1 - 0.059 13.3 3.3 9.3 6.2 0.0 2.6 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 Menin PF05053.8 ETO35799.1 - 0.091 10.9 4.1 0.11 10.5 2.9 1.2 1 0 0 1 1 1 0 Menin ATP-grasp_4 PF13535.1 ETO35800.1 - 1.7e-22 80.0 0.0 6.9e-13 48.7 0.0 2.3 1 1 1 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 ETO35800.1 - 9.9e-10 37.6 0.0 1.3e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 ETO35800.1 - 2e-06 27.2 0.0 0.015 14.5 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 ETO35800.1 - 0.0032 17.3 0.0 0.19 11.5 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.6 ETO35800.1 - 0.033 13.6 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATP-grasp domain DUF2457 PF10446.4 ETO35800.1 - 1.1 7.9 8.7 2.2 6.8 6.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF1687 PF07955.6 ETO35801.1 - 0.26 11.2 3.2 0.33 10.9 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1687) DUF2681 PF10883.3 ETO35801.1 - 6.1 7.1 7.5 0.57 10.4 1.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) Lumazine_bd PF12870.2 ETO35802.1 - 7.8 6.5 10.3 12 6.0 2.6 2.6 1 1 2 3 3 3 0 Lumazine-binding domain ERAP1_C PF11838.3 ETO35803.1 - 1.1e-35 123.4 0.0 1.4e-29 103.4 0.0 2.5 1 1 1 2 2 2 2 ERAP1-like C-terminal domain LRR_6 PF13516.1 ETO35805.1 - 4.8e-06 26.0 4.6 0.24 11.5 0.1 4.1 2 1 1 3 3 3 3 Leucine Rich repeat LRR_8 PF13855.1 ETO35805.1 - 0.0022 17.7 4.5 0.025 14.3 1.1 2.6 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.2 ETO35805.1 - 5.8 6.6 13.7 3 7.5 1.8 3.6 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) XRN_N PF03159.13 ETO35806.1 - 0.15 11.4 0.0 0.15 11.4 0.0 2.3 2 1 0 2 2 2 0 XRN 5'-3' exonuclease N-terminus Toxin_10 PF05431.6 ETO35806.1 - 0.17 11.5 5.0 0.27 10.8 3.4 1.3 1 0 0 1 1 1 0 Insecticidal Crystal Toxin, P42 WD40 PF00400.27 ETO35807.1 - 1.1e-60 199.4 31.6 2.1e-10 40.0 1.9 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO35807.1 - 1e-10 40.3 11.6 0.012 13.7 0.4 5.5 1 1 5 6 6 6 6 Nucleoporin Nup120/160 DNA_primase_S PF01896.14 ETO35808.1 - 3.6e-43 146.8 0.6 6.6e-43 145.9 0.4 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit MecA PF05389.7 ETO35810.1 - 0.0014 18.2 4.8 0.0014 18.2 3.4 1.6 2 0 0 2 2 2 1 Negative regulator of genetic competence (MecA) Oxidored_q2 PF00420.19 ETO35810.1 - 0.029 13.9 0.0 0.066 12.8 0.0 1.5 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Pox_A3L PF05288.6 ETO35811.1 - 0.039 13.6 0.8 0.054 13.2 0.5 1.3 1 1 0 1 1 1 0 Poxvirus A3L Protein WD40 PF00400.27 ETO35812.1 - 9.3e-77 250.4 19.2 3.1e-12 45.8 0.7 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat PQQ_2 PF13360.1 ETO35812.1 - 1e-06 28.3 1.8 2e-05 24.1 0.3 2.4 1 1 0 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO35812.1 - 1.5e-06 26.7 2.0 0.011 14.0 0.1 3.4 1 1 3 4 4 4 3 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO35812.1 - 8.8e-05 21.4 13.6 0.15 10.7 0.2 4.7 1 1 3 4 4 4 3 Nup133 N terminal like Me-amine-dh_H PF06433.6 ETO35812.1 - 0.00015 20.5 0.1 0.041 12.5 0.0 2.9 1 1 2 3 3 3 2 Methylamine dehydrogenase heavy chain (MADH) Resistin PF06954.6 ETO35812.1 - 0.00051 20.2 3.3 1.7 8.9 0.3 3.7 3 2 2 5 5 5 2 Resistin PQQ PF01011.16 ETO35812.1 - 0.013 14.9 0.0 5.8 6.6 0.0 4.1 4 0 0 4 4 4 0 PQQ enzyme repeat SusE PF14292.1 ETO35812.1 - 0.056 13.2 0.2 8.4 6.2 0.0 3.2 4 0 0 4 4 4 0 SusE outer membrane protein PD40 PF07676.7 ETO35812.1 - 0.74 9.5 12.4 8.4 6.1 0.1 4.9 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Herpes_BLRF2 PF05812.7 ETO35815.1 - 0.00037 20.2 2.7 0.00084 19.1 1.9 1.6 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein bZIP_1 PF00170.16 ETO35815.1 - 0.013 15.4 6.3 0.013 15.4 4.4 2.0 2 0 0 2 2 2 0 bZIP transcription factor DivIC PF04977.10 ETO35815.1 - 0.024 14.1 3.5 0.05 13.1 2.4 1.5 1 0 0 1 1 1 0 Septum formation initiator VanY PF02557.12 ETO35815.1 - 0.066 13.0 1.0 0.092 12.5 0.2 1.7 1 1 1 2 2 2 0 D-alanyl-D-alanine carboxypeptidase DUF3373 PF11853.3 ETO35815.1 - 0.089 11.3 0.8 0.13 10.8 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) bZIP_2 PF07716.10 ETO35815.1 - 0.36 10.6 10.1 0.2 11.4 4.7 2.3 3 0 0 3 3 3 0 Basic region leucine zipper Rab5-bind PF09311.6 ETO35815.1 - 1.8 8.4 10.9 0.1 12.4 3.7 1.7 2 0 0 2 2 2 0 Rabaptin-like protein WD40 PF00400.27 ETO35816.1 - 4e-60 197.6 25.4 2e-13 49.6 0.6 6.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Proteasome_A_N PF10584.4 ETO35816.1 - 2.7e-06 26.6 1.6 1.2 8.5 0.0 4.7 5 0 0 5 5 5 2 Proteasome subunit A N-terminal signature PD40 PF07676.7 ETO35816.1 - 1.8e-05 24.2 1.7 6.4 6.5 0.0 5.0 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO35816.1 - 0.00024 19.3 1.1 0.23 9.5 0.1 2.3 1 1 0 2 2 2 2 Nucleoporin Nup120/160 DPPIV_N PF00930.16 ETO35816.1 - 0.0022 16.6 0.0 15 4.0 0.0 3.9 1 1 1 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nbas_N PF15492.1 ETO35816.1 - 0.0027 16.8 0.1 0.13 11.3 0.0 3.1 1 1 3 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 ETO35816.1 - 0.003 16.3 2.2 3 6.5 0.1 3.4 1 1 2 3 3 3 2 Nup133 N terminal like UBA_e1_C PF09358.5 ETO35816.1 - 1.8 8.7 4.8 4.2 7.5 2.5 2.1 2 0 0 2 2 2 0 Ubiquitin-activating enzyme e1 C-terminal domain Img2 PF05046.9 ETO35817.1 - 0.00076 19.6 0.4 0.027 14.6 0.3 2.5 1 1 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) LRR_1 PF00560.28 ETO35818.1 - 6.5e-12 43.7 24.5 0.57 10.4 0.3 10.4 10 0 0 10 10 10 6 Leucine Rich Repeat LRR_4 PF12799.2 ETO35818.1 - 3.1e-11 42.6 28.1 0.0017 17.9 3.0 6.0 3 3 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO35818.1 - 9e-09 34.9 21.8 0.0032 17.2 2.7 4.8 4 1 0 5 5 5 4 Leucine rich repeat LRR_6 PF13516.1 ETO35818.1 - 5.2 7.4 20.7 8.8 6.7 0.0 7.3 8 0 0 8 8 8 0 Leucine Rich repeat G-alpha PF00503.15 ETO35819.1 - 1.2e-34 119.6 10.1 2.7e-18 65.8 0.4 2.1 1 1 0 2 2 2 2 G-protein alpha subunit Antiterm PF03589.8 ETO35819.1 - 0.059 13.4 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Antitermination protein EF-hand_7 PF13499.1 ETO35820.1 - 0.11 12.7 0.1 0.26 11.4 0.0 1.6 2 0 0 2 2 2 0 EF-hand domain pair V_ATPase_I PF01496.14 ETO35821.1 - 5.9e-06 24.4 2.2 6.4e-06 24.3 1.5 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF3040 PF11239.3 ETO35821.1 - 0.012 15.5 1.8 0.054 13.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Cortex-I_coil PF09304.5 ETO35821.1 - 6.4 6.8 11.4 0.056 13.4 1.5 2.2 2 1 1 3 3 3 0 Cortexillin I, coiled coil Trypan_glycop PF00913.14 ETO35822.1 - 0.37 9.6 1.6 0.43 9.4 1.1 1.2 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) Exo_endo_phos_2 PF14529.1 ETO35823.1 - 0.00024 20.7 0.1 0.00048 19.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase YopX PF09643.5 ETO35823.1 - 0.014 15.3 1.6 0.029 14.3 1.1 1.5 1 0 0 1 1 1 0 YopX protein KIP1 PF07765.7 ETO35823.1 - 2.2 8.2 5.5 2.2 8.1 0.0 3.0 3 1 0 3 3 3 0 KIP1-like protein TPR_11 PF13414.1 ETO35826.1 - 1.8e-22 78.7 3.2 3.4e-10 39.4 0.1 4.2 2 1 1 4 4 4 3 TPR repeat TPR_1 PF00515.23 ETO35826.1 - 8.2e-17 60.0 1.2 0.00042 19.8 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO35826.1 - 7.9e-15 53.7 3.5 0.0017 18.4 0.1 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO35826.1 - 1e-12 46.8 2.1 0.00071 19.3 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO35826.1 - 1.4e-12 47.0 0.2 0.036 14.6 0.0 5.0 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETO35826.1 - 3e-11 43.6 0.2 0.00041 20.9 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO35826.1 - 2.4e-09 36.9 4.9 0.0037 17.1 0.3 3.5 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO35826.1 - 5.6e-06 25.7 0.5 1.3 8.9 0.0 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO35826.1 - 6.6e-06 26.3 1.1 1.8 8.9 0.0 3.5 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO35826.1 - 0.00026 20.5 0.3 21 5.1 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO35826.1 - 0.0043 17.4 0.4 10 6.8 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat NRDE-2 PF08424.5 ETO35826.1 - 0.02 13.7 0.1 0.03 13.2 0.1 1.3 1 1 0 1 1 1 0 NRDE-2, necessary for RNA interference TPR_11 PF13414.1 ETO35827.1 - 0.00046 19.7 0.0 0.00095 18.7 0.0 1.5 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 ETO35827.1 - 0.0043 16.8 0.0 0.0097 15.7 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO35827.1 - 0.15 11.7 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat LINES_N PF14694.1 ETO35828.1 - 6.3e-12 45.4 2.9 6.3e-12 45.4 2.0 1.9 1 1 1 2 2 2 1 Lines N-terminus LINES_C PF14695.1 ETO35828.1 - 2e-07 30.1 0.1 4.9e-07 28.8 0.1 1.7 1 0 0 1 1 1 1 Lines C-terminus PTR PF12789.2 ETO35828.1 - 0.052 13.3 2.0 0.076 12.8 0.1 2.3 2 0 0 2 2 2 0 Phage tail repeat like Opiods_neuropep PF01160.13 ETO35829.1 - 0.16 11.7 0.2 0.16 11.7 0.1 3.1 3 1 0 3 3 3 0 Vertebrate endogenous opioids neuropeptide RRM_6 PF14259.1 ETO35830.1 - 4.8e-29 100.1 0.1 6.7e-13 48.4 0.0 4.0 4 1 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO35830.1 - 2.8e-19 68.5 0.1 0.00012 21.6 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO35830.1 - 0.021 14.6 0.0 1.8 8.5 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 ETO35830.1 - 0.054 13.3 0.1 1.1 9.1 0.0 2.9 3 1 0 3 3 3 0 RNA binding motif Peptidase_S10 PF00450.17 ETO35831.1 - 8.4e-22 77.9 0.4 9.6e-22 77.7 0.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase GIDA_assoc_3 PF13932.1 ETO35833.1 - 0.15 12.0 3.9 0.2 11.7 0.0 3.1 3 0 0 3 3 3 0 GidA associated domain 3 MBOAT_2 PF13813.1 ETO35834.1 - 4.1e-06 26.7 3.1 0.0035 17.3 2.1 2.4 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family DUF1700 PF08006.6 ETO35834.1 - 0.072 12.3 5.0 0.063 12.5 2.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1700) VIT1 PF01988.14 ETO35834.1 - 0.097 12.1 0.9 0.15 11.5 0.6 1.4 1 1 0 1 1 1 0 VIT family Git3_C PF11970.3 ETO35836.1 - 1.2e-05 24.9 1.0 1.2e-05 24.9 0.7 2.0 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 ETO35836.1 - 2.7e-05 23.4 0.0 3.6e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MRAP PF15183.1 ETO35836.1 - 0.018 14.6 0.1 0.018 14.6 0.0 2.1 2 1 1 3 3 3 0 Melanocortin-2 receptor accessory protein family RNA_pol_3_Rpc31 PF11705.3 ETO35837.1 - 0.0019 18.2 13.4 0.0019 18.2 9.3 2.0 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.7 ETO35837.1 - 0.039 11.8 20.4 0.079 10.8 14.1 1.4 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 ETO35837.1 - 0.075 11.7 26.5 0.17 10.6 18.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF1510 PF07423.6 ETO35837.1 - 0.12 11.7 21.8 0.24 10.7 15.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FAM176 PF14851.1 ETO35837.1 - 1.6 8.4 11.6 4.6 6.9 8.1 1.8 1 0 0 1 1 1 0 FAM176 family BSP_II PF05432.6 ETO35837.1 - 8.8 5.5 26.6 14 4.8 18.5 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TUDOR PF00567.19 ETO35838.1 - 0.0024 17.7 0.9 0.017 14.9 0.0 2.7 3 0 0 3 3 3 1 Tudor domain LIN37 PF15306.1 ETO35838.1 - 0.17 11.9 3.2 0.37 10.7 2.2 1.6 1 1 0 1 1 1 0 LIN37 AAA_11 PF13086.1 ETO35839.1 - 0.0032 17.0 0.8 0.013 15.0 0.4 1.9 1 1 1 2 2 2 1 AAA domain DUF843 PF05814.6 ETO35839.1 - 0.077 12.8 2.5 0.13 12.0 1.8 1.4 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) Cyc-maltodext_C PF10438.4 ETO35839.1 - 0.4 10.7 2.1 1.1 9.3 0.2 2.1 1 1 1 2 2 2 0 Cyclo-malto-dextrinase C-terminal domain CxxCxxCC PF03692.10 ETO35839.1 - 0.95 9.9 3.3 3.9 8.0 2.3 1.8 1 1 0 1 1 1 0 Putative zinc- or iron-chelating domain Nol1_Nop2_Fmu PF01189.12 ETO35840.1 - 3.9e-19 69.1 0.0 4.1e-09 36.2 0.0 2.3 2 0 0 2 2 2 2 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 ETO35840.1 - 3.5e-07 29.9 0.1 1.1e-05 25.1 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 ETO35840.1 - 2.3e-05 24.4 0.1 7e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 ETO35840.1 - 5.2e-05 23.5 0.0 0.0007 19.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO35840.1 - 7.9e-05 23.2 0.0 0.00021 21.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETO35840.1 - 0.00093 19.2 0.0 0.0014 18.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETO35840.1 - 0.016 14.3 0.0 0.032 13.3 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Aminotran_4 PF01063.14 ETO35840.1 - 0.035 13.5 0.2 0.13 11.6 0.1 1.9 2 0 0 2 2 2 0 Aminotransferase class IV Methyltransf_23 PF13489.1 ETO35840.1 - 0.045 13.4 0.0 0.22 11.2 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 ETO35840.1 - 0.047 14.1 0.0 0.23 11.9 0.0 2.2 3 0 0 3 3 2 0 Methyltransferase domain PCMT PF01135.14 ETO35840.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Kei1 PF08552.6 ETO35841.1 - 0.0026 17.4 0.5 0.0033 17.1 0.3 1.2 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF4271 PF14093.1 ETO35841.1 - 0.01 15.5 0.5 0.012 15.3 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) DUF4208 PF13907.1 ETO35841.1 - 0.011 15.9 1.1 0.011 15.9 0.8 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) Syntaxin PF00804.20 ETO35841.1 - 0.029 14.5 1.6 0.046 13.8 1.1 1.3 1 0 0 1 1 1 0 Syntaxin DUF4108 PF13390.1 ETO35842.1 - 0.057 13.1 3.0 0.077 12.7 2.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4108) Claudin_3 PF06653.6 ETO35843.1 - 0.0095 15.6 3.5 0.012 15.2 2.0 1.4 1 1 0 1 1 1 1 Tight junction protein, Claudin-like DUF2721 PF11026.3 ETO35843.1 - 0.034 13.7 0.1 0.034 13.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF4131 PF13567.1 ETO35843.1 - 0.18 11.2 1.7 0.23 10.8 0.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) MARVEL PF01284.18 ETO35843.1 - 0.33 10.7 6.0 0.42 10.4 3.4 1.7 1 1 1 2 2 2 0 Membrane-associating domain zf-TRAF PF02176.13 ETO35844.1 - 9.7e-05 22.6 6.9 0.00019 21.7 1.9 2.8 2 0 0 2 2 2 1 TRAF-type zinc finger Sina PF03145.11 ETO35844.1 - 0.00013 21.7 6.8 0.00064 19.4 3.1 2.8 2 1 1 3 3 3 2 Seven in absentia protein family Imm42 PF15601.1 ETO35844.1 - 0.032 13.6 0.9 0.1 12.0 0.6 1.9 1 0 0 1 1 1 0 Immunity protein 42 RNF111_N PF15303.1 ETO35847.1 - 0.15 11.5 10.9 0.2 11.1 7.5 1.1 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus Peptidase_S49_N PF08496.5 ETO35847.1 - 0.58 9.9 3.7 0.71 9.6 2.6 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CHAT PF12770.2 ETO35848.1 - 1.6e-11 43.8 0.1 3.4e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 CHAT domain EFG_II PF14492.1 ETO35848.1 - 0.02 14.7 0.1 0.093 12.5 0.0 2.2 2 0 0 2 2 2 0 Elongation Factor G, domain II Peptidase_C25 PF01364.13 ETO35848.1 - 0.11 11.4 0.0 0.22 10.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family C25 CobT PF06213.7 ETO35849.1 - 0.0011 18.1 9.2 0.0012 18.0 6.3 1.2 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Zip PF02535.17 ETO35849.1 - 0.49 9.3 5.4 0.52 9.2 3.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Menin PF05053.8 ETO35849.1 - 2.2 6.3 14.8 2.6 6.1 10.3 1.1 1 0 0 1 1 1 0 Menin RCR PF12273.3 ETO35849.1 - 6.9 7.2 13.3 8.7 6.9 9.2 1.1 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red INTS2 PF14750.1 ETO35851.1 - 0.024 12.1 1.4 0.037 11.5 0.2 1.8 2 0 0 2 2 2 0 Integrator complex subunit 2 Fe_dep_repr_C PF02742.10 ETO35851.1 - 0.18 11.5 1.6 1.2 8.8 0.0 2.7 2 1 1 3 3 3 0 Iron dependent repressor, metal binding and dimerisation domain PTS_EIIC PF02378.13 ETO35852.1 - 0.056 12.2 0.0 0.071 11.9 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase system, EIIC DUF4181 PF13789.1 ETO35852.1 - 0.091 12.6 1.8 0.16 11.9 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) IFN-gamma PF00714.12 ETO35852.1 - 0.1 12.4 0.8 0.16 11.8 0.5 1.3 1 0 0 1 1 1 0 Interferon gamma WD40 PF00400.27 ETO35853.1 - 1.2e-81 265.9 14.1 1.3e-11 43.9 0.0 7.0 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO35853.1 - 2.4e-09 36.0 2.5 4.8e-06 25.1 0.1 3.0 1 1 2 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.3 ETO35853.1 - 1.4e-07 30.0 12.3 0.056 11.5 0.0 5.3 1 1 3 4 4 4 3 Nucleoporin Nup120/160 SGL PF08450.7 ETO35853.1 - 2.2e-05 23.9 1.8 0.036 13.4 0.1 3.1 1 1 2 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region Nucleoporin_N PF08801.6 ETO35853.1 - 0.00014 20.7 15.2 0.016 13.9 4.0 4.2 1 1 1 2 2 2 2 Nup133 N terminal like TFIIIC_delta PF12657.2 ETO35853.1 - 0.0018 18.0 3.2 0.023 14.4 0.2 2.6 2 1 0 2 2 2 1 Transcription factor IIIC subunit delta N-term Coatomer_WDAD PF04053.9 ETO35853.1 - 0.0024 16.7 3.9 0.28 9.9 0.3 3.1 1 1 1 3 3 3 1 Coatomer WD associated region Hira PF07569.6 ETO35853.1 - 0.0029 16.8 1.9 2.5 7.2 0.0 3.7 2 2 2 4 4 4 1 TUP1-like enhancer of split Nbas_N PF15492.1 ETO35853.1 - 0.003 16.7 2.2 4.1 6.4 0.0 3.5 1 1 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Resistin PF06954.6 ETO35853.1 - 0.0057 16.8 0.0 13 6.1 0.0 3.7 1 1 3 4 4 4 0 Resistin Ricin_B_lectin PF00652.17 ETO35853.1 - 0.0091 16.0 2.9 0.75 9.8 0.1 3.0 1 1 1 3 3 3 1 Ricin-type beta-trefoil lectin domain PD40 PF07676.7 ETO35853.1 - 0.018 14.6 8.3 13 5.5 0.0 5.7 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 ETO35853.1 - 0.032 12.8 0.6 3.8 6.0 0.0 3.3 1 1 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region GATase PF00117.23 ETO35853.1 - 0.041 13.3 0.2 10 5.4 0.0 3.6 2 2 1 3 3 3 0 Glutamine amidotransferase class-I UN_NPL4 PF11543.3 ETO35853.1 - 0.3 11.3 1.8 24 5.2 0.1 3.6 3 2 1 4 4 4 0 Nuclear pore localisation protein NPL4 DUF3127 PF11325.3 ETO35853.1 - 0.48 10.4 2.6 11 6.0 0.3 3.0 3 1 0 3 3 2 0 Domain of unknown function (DUF3127) Proteasome_A_N PF10584.4 ETO35853.1 - 1.9 7.8 9.0 54 3.2 0.0 5.2 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Kelch_6 PF13964.1 ETO35854.1 - 0.00045 20.2 0.0 0.0085 16.2 0.0 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.1 ETO35854.1 - 0.0042 17.0 0.2 0.013 15.3 0.1 1.9 1 0 0 1 1 1 1 Kelch motif Kelch_3 PF13415.1 ETO35854.1 - 0.0081 16.2 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO35854.1 - 0.047 13.4 0.3 1.9 8.3 0.0 2.7 3 0 0 3 3 3 0 Galactose oxidase, central domain BUD22 PF09073.5 ETO35856.1 - 0.0088 15.1 24.8 0.011 14.8 17.2 1.0 1 0 0 1 1 1 1 BUD22 Paf1 PF03985.8 ETO35856.1 - 0.026 13.2 26.2 0.032 12.9 18.2 1.0 1 0 0 1 1 1 0 Paf1 AAA_11 PF13086.1 ETO35856.1 - 0.12 11.9 10.6 0.16 11.5 7.3 1.2 1 0 0 1 1 1 0 AAA domain DNA_pol_phi PF04931.8 ETO35856.1 - 0.36 8.5 23.4 0.45 8.2 16.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi Anoctamin PF04547.7 ETO35856.1 - 0.57 8.7 5.1 0.77 8.3 3.6 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel AAA_23 PF13476.1 ETO35856.1 - 0.66 10.2 29.2 0.9 9.8 20.2 1.2 1 0 0 1 1 1 0 AAA domain FLO_LFY PF01698.11 ETO35856.1 - 0.84 8.4 13.3 1.1 7.9 9.2 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein SprA-related PF12118.3 ETO35856.1 - 3.6 6.8 24.5 5 6.3 17.0 1.2 1 0 0 1 1 1 0 SprA-related family RR_TM4-6 PF06459.7 ETO35856.1 - 3.9 7.3 23.3 5.3 6.8 16.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 WD40 PF00400.27 ETO35857.1 - 6.8e-12 44.7 4.9 8.6e-06 25.4 0.0 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat WD40 PF00400.27 ETO35858.1 - 2e-64 211.3 32.1 7.4e-12 44.6 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO35858.1 - 3.5e-10 38.6 7.0 0.043 11.9 0.0 5.0 2 2 1 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO35858.1 - 3.5e-05 22.7 12.0 0.025 13.3 1.6 4.7 1 1 2 4 4 4 3 Nup133 N terminal like DUF1900 PF08954.6 ETO35858.1 - 0.017 14.6 0.1 5.3 6.5 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF1900) DUF1030 PF06270.6 ETO35858.1 - 0.12 11.9 1.1 1.4 8.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1030) DUF4221 PF13970.1 ETO35858.1 - 0.5 9.6 8.9 0.62 9.3 4.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4221) WD40 PF00400.27 ETO35859.1 - 1.5e-38 129.3 9.6 1e-08 34.7 0.1 7.4 7 1 0 7 7 7 6 WD domain, G-beta repeat PD40 PF07676.7 ETO35859.1 - 1e-06 28.2 0.1 0.056 13.1 0.0 3.8 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO35859.1 - 1.7e-05 23.2 0.4 0.00056 18.3 0.0 2.5 2 1 1 3 3 3 1 Cytochrome D1 heme domain Nup160 PF11715.3 ETO35859.1 - 6.6e-05 21.2 0.3 0.039 12.0 0.0 2.9 1 1 0 2 2 2 2 Nucleoporin Nup120/160 RicinB_lectin_2 PF14200.1 ETO35859.1 - 0.022 15.1 2.7 0.034 14.5 0.0 2.6 3 0 0 3 3 3 0 Ricin-type beta-trefoil lectin domain-like Proteasome_A_N PF10584.4 ETO35859.1 - 0.097 12.0 0.4 16 4.9 0.0 3.1 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 ETO35860.1 - 5e-58 191.0 27.7 1.7e-13 49.8 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO35860.1 - 0.00032 18.9 6.0 0.037 12.1 0.6 3.9 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 ETO35860.1 - 0.0043 16.1 0.2 0.026 13.6 0.1 2.5 1 1 0 1 1 1 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 ETO35860.1 - 0.082 12.5 2.4 26 4.5 0.0 4.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat LIM_bind PF01803.11 ETO35861.1 - 0.004 16.3 1.5 0.004 16.3 1.1 1.6 1 1 1 2 2 2 1 LIM-domain binding protein DUF4339 PF14237.1 ETO35861.1 - 0.022 14.3 0.1 0.047 13.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4339) Kelch_4 PF13418.1 ETO35861.1 - 0.068 12.9 0.2 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 Galactose oxidase, central domain WD40 PF00400.27 ETO35862.1 - 1.9e-39 132.1 12.0 8.5e-10 38.1 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO35862.1 - 0.00096 17.3 0.8 0.38 8.8 0.1 3.3 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Mid2 PF04478.7 ETO35862.1 - 0.0015 17.9 2.0 0.87 8.9 0.0 3.2 3 1 1 4 4 4 2 Mid2 like cell wall stress sensor Peptidase_C69 PF03577.10 ETO35862.1 - 0.0024 16.8 0.6 0.66 8.7 0.0 3.2 4 0 0 4 4 4 2 Peptidase family C69 PD40 PF07676.7 ETO35862.1 - 0.31 10.7 2.4 10 5.9 0.0 3.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat LRR_4 PF12799.2 ETO35863.1 - 7.6e-14 50.9 51.9 3.6e-06 26.4 2.0 8.0 3 1 6 9 9 9 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETO35863.1 - 1.2e-08 34.5 34.0 6.4e-05 22.6 5.1 5.2 4 2 2 6 6 6 4 Leucine rich repeat LRR_1 PF00560.28 ETO35863.1 - 0.0067 16.3 4.2 0.069 13.2 0.3 10.8 13 1 0 13 13 13 2 Leucine Rich Repeat LRR_6 PF13516.1 ETO35863.1 - 0.99 9.6 0.1 0.99 9.6 0.0 7.3 6 1 2 8 8 8 0 Leucine Rich repeat LRR_7 PF13504.1 ETO35863.1 - 9.4 6.9 21.6 3.9 8.1 0.1 7.3 8 0 0 8 8 8 0 Leucine rich repeat HSP70 PF00012.15 ETO35864.1 - 1.5e-161 538.3 2.8 2e-161 537.9 2.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 ETO35864.1 - 8.4e-13 47.6 0.3 3.7e-12 45.4 0.2 1.8 1 1 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.11 ETO35864.1 - 0.0077 15.8 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 ETO35864.1 - 0.016 14.0 0.2 0.38 9.5 0.1 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Glt_symporter PF03616.9 ETO35864.1 - 0.066 11.7 0.2 0.11 10.9 0.1 1.3 1 0 0 1 1 1 0 Sodium/glutamate symporter DUF3153 PF11353.3 ETO35864.1 - 0.093 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) 7tm_4 PF13853.1 ETO35865.1 - 1.2 8.9 8.0 0.4 10.4 2.2 2.0 2 0 0 2 2 2 0 Olfactory receptor bZIP_1 PF00170.16 ETO35867.1 - 2.2e-08 33.8 7.8 5.6e-08 32.6 5.4 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 ETO35867.1 - 1.7e-05 24.5 9.7 4.6e-05 23.1 6.7 1.8 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 ETO35867.1 - 0.43 10.8 11.2 0.028 14.6 3.9 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor SNARE PF05739.14 ETO35868.1 - 2.8e-09 36.5 8.7 2e-08 33.7 4.9 2.6 2 0 0 2 2 2 1 SNARE domain V-SNARE_C PF12352.3 ETO35868.1 - 5.8e-06 26.2 10.8 0.035 14.1 0.1 3.3 3 0 0 3 3 3 3 Snare region anchored in the vesicle membrane C-terminus MCPsignal PF00015.16 ETO35868.1 - 0.55 9.7 8.9 0.053 13.0 2.5 1.9 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.6 ETO35868.1 - 2.1 8.2 9.8 37 4.2 1.3 3.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) VIT1 PF01988.14 ETO35868.1 - 6.1 6.2 6.6 0.67 9.3 0.8 1.9 2 0 0 2 2 2 0 VIT family DUF2263 PF10021.4 ETO35869.1 - 3.2e-25 88.8 1.4 5.2e-13 49.2 0.0 2.5 2 1 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2263) DUF3959 PF13105.1 ETO35869.1 - 0.01 15.1 0.4 0.016 14.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) WD40 PF00400.27 ETO35870.1 - 6.6e-14 51.1 2.4 3.1e-11 42.6 0.3 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO35870.1 - 0.048 12.4 0.1 0.06 12.0 0.1 1.3 1 0 0 1 1 1 0 Nup133 N terminal like Blo-t-5 PF11642.3 ETO35871.1 - 0.095 12.4 2.8 8.2 6.2 0.0 2.2 2 0 0 2 2 2 0 Mite allergen Blo t 5 Viral_env_E26 PF11050.3 ETO35871.1 - 4.3 6.4 7.5 2.2 7.4 3.3 1.7 2 0 0 2 2 2 0 Virus envelope protein E26 Mitofilin PF09731.4 ETO35872.1 - 2.2e-09 36.5 0.0 2.2e-09 36.5 0.0 2.6 2 1 1 3 3 3 1 Mitochondrial inner membrane protein HTH_28 PF13518.1 ETO35872.1 - 0.037 14.0 0.4 0.42 10.6 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HYR PF02494.11 ETO35873.1 - 6.5e-25 86.9 1.2 1.8e-07 31.0 0.0 4.5 3 1 0 4 4 4 4 HYR domain SpoIIID PF12116.3 ETO35873.1 - 0.0075 16.1 0.0 0.036 13.9 0.0 2.2 1 0 0 1 1 1 1 Stage III sporulation protein D Methyltransf_25 PF13649.1 ETO35874.1 - 3.3e-09 36.9 0.0 6.9e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETO35874.1 - 3.9e-09 36.8 0.1 3.6e-08 33.8 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain TehB PF03848.9 ETO35874.1 - 1.4e-06 27.6 0.6 1.9e-06 27.1 0.4 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB NodS PF05401.6 ETO35874.1 - 9.7e-06 25.1 0.1 1.4e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_PK PF05891.7 ETO35874.1 - 4.5e-05 22.8 0.2 6.8e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Phage_RpbA PF10789.4 ETO35874.1 - 0.016 15.0 0.4 0.097 12.5 0.0 2.2 2 0 0 2 2 2 0 Phage RNA polymerase binding, RpbA Alpha-amylase_N PF02903.9 ETO35875.1 - 0.059 13.3 0.0 0.092 12.7 0.0 1.3 1 0 0 1 1 1 0 Alpha amylase, N-terminal ig-like domain DUF2924 PF11149.3 ETO35875.1 - 0.11 12.5 0.2 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) NAD_binding_4 PF07993.7 ETO35876.1 - 1.9e-52 177.7 0.0 5e-52 176.2 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein Sterile PF03015.14 ETO35876.1 - 3.6e-07 30.3 2.5 3.6e-07 30.3 1.7 3.3 3 1 0 3 3 3 1 Male sterility protein 3Beta_HSD PF01073.14 ETO35876.1 - 2e-06 26.7 0.4 0.00036 19.3 0.1 3.0 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 ETO35876.1 - 0.0013 18.2 0.1 0.013 14.9 0.0 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 ETO35876.1 - 0.024 13.5 2.9 0.39 9.5 0.0 3.1 3 1 0 3 3 3 0 Polysaccharide biosynthesis protein Ldh_1_C PF02866.13 ETO35877.1 - 1.1e-16 61.1 0.0 1.2e-16 60.9 0.0 1.0 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Arg_tRNA_synt_N PF03485.11 ETO35878.1 - 0.029 14.8 0.1 0.031 14.8 0.1 1.2 1 1 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain Pik1 PF11522.3 ETO35878.1 - 0.54 10.0 2.5 12 5.7 0.1 2.6 1 1 1 2 2 2 0 Yeast phosphatidylinositol-4-OH kinase Pik1 Kelch_4 PF13418.1 ETO35879.1 - 2e-06 27.4 0.5 0.0017 18.0 0.1 3.2 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO35879.1 - 6.4e-05 22.4 4.9 0.00012 21.5 0.2 3.3 3 1 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO35879.1 - 0.00019 21.0 0.1 0.19 11.5 0.0 3.6 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 ETO35879.1 - 0.0098 16.0 3.6 0.059 13.5 0.4 3.1 2 1 1 3 3 3 1 Kelch motif Kelch_5 PF13854.1 ETO35879.1 - 0.06 13.3 0.4 0.67 9.9 0.3 2.7 3 0 0 3 3 3 0 Kelch motif WD40 PF00400.27 ETO35880.1 - 3.6e-12 45.6 0.4 9.6e-12 44.3 0.2 1.7 2 0 0 2 2 2 1 WD domain, G-beta repeat NEAT PF05031.7 ETO35880.1 - 0.032 14.2 0.1 0.066 13.2 0.0 1.5 2 0 0 2 2 2 0 Iron Transport-associated domain CAAP1 PF15335.1 ETO35881.1 - 0.1 12.8 1.0 0.24 11.6 0.7 1.7 1 0 0 1 1 1 0 Caspase activity and apoptosis inhibitor 1 DUF3258 PF11646.3 ETO35881.1 - 0.13 12.4 2.6 0.16 12.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF3258 CAP_GLY PF01302.20 ETO35882.1 - 2.2e-18 65.7 4.9 5.3e-08 32.4 0.1 4.2 3 1 0 3 3 3 3 CAP-Gly domain PH_BEACH PF14844.1 ETO35882.1 - 0.014 15.2 0.0 0.11 12.3 0.0 2.3 2 0 0 2 2 2 0 PH domain associated with Beige/BEACH TP6A_N PF04406.9 ETO35883.1 - 0.013 15.1 0.1 0.049 13.3 0.1 2.0 1 0 0 1 1 1 0 Type IIB DNA topoisomerase FANCI_S3 PF14677.1 ETO35883.1 - 0.084 12.2 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 FANCI solenoid 3 Mitofilin PF09731.4 ETO35883.1 - 0.47 9.0 7.6 0.92 8.0 5.2 1.5 1 1 0 1 1 1 0 Mitochondrial inner membrane protein Mucin PF01456.12 ETO35883.1 - 1.6 8.5 22.8 3.3 7.4 15.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.3 ETO35883.1 - 5.8 6.6 12.9 12 5.6 9.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Apt1 PF10351.4 ETO35884.1 - 9.9e-09 34.5 9.6 5.9e-08 32.0 6.2 2.6 1 1 0 1 1 1 1 Golgi-body localisation protein domain DUF3439 PF11921.3 ETO35884.1 - 0.78 9.4 7.5 2.1 8.1 5.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Kelch_1 PF01344.20 ETO35886.1 - 3.1e-07 29.8 2.7 0.00098 18.6 0.5 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETO35886.1 - 1.9e-05 24.6 1.5 0.049 13.8 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 ETO35886.1 - 0.00089 19.3 0.0 0.2 11.8 0.0 2.8 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO35886.1 - 0.0011 18.7 0.0 2.4 7.9 0.0 3.7 3 0 0 3 3 3 2 Galactose oxidase, central domain U-box PF04564.10 ETO35887.1 - 3e-13 49.5 0.0 1.1e-12 47.7 0.0 2.0 1 0 0 1 1 1 1 U-box domain MbeD_MobD PF04899.7 ETO35887.1 - 0.00033 20.4 0.9 0.00096 19.0 0.7 1.8 1 0 0 1 1 1 1 MbeD/MobD like DUF3793 PF12672.2 ETO35887.1 - 0.0044 16.6 0.2 0.0074 15.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3793) Mnd1 PF03962.10 ETO35887.1 - 0.019 14.6 9.3 0.049 13.2 6.5 1.8 1 0 0 1 1 1 0 Mnd1 family DUF2205 PF10224.4 ETO35887.1 - 0.032 13.8 1.0 0.032 13.8 0.7 1.9 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) V_ATPase_I PF01496.14 ETO35887.1 - 0.036 11.9 4.6 0.043 11.6 3.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CR6_interact PF10147.4 ETO35887.1 - 0.044 13.0 8.2 0.069 12.4 5.7 1.4 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 MitMem_reg PF13012.1 ETO35887.1 - 0.069 13.2 0.1 0.069 13.2 0.0 3.0 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function DivIVA PF05103.8 ETO35887.1 - 0.13 12.3 9.3 0.3 11.1 6.4 1.6 1 0 0 1 1 1 0 DivIVA protein DUF2315 PF10231.4 ETO35887.1 - 0.17 11.7 6.1 0.39 10.5 4.0 1.8 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2315) AAA_32 PF13654.1 ETO35887.1 - 0.22 10.1 3.9 0.32 9.5 2.7 1.3 1 0 0 1 1 1 0 AAA domain DUF4200 PF13863.1 ETO35887.1 - 0.33 10.8 15.2 0.78 9.6 10.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) ALIX_LYPXL_bnd PF13949.1 ETO35887.1 - 0.5 9.2 14.0 1.8 7.4 8.4 2.1 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV HAP1_N PF04849.8 ETO35887.1 - 0.73 8.7 14.5 2.8 6.7 10.0 1.9 1 1 0 1 1 1 0 HAP1 N-terminal conserved region ATP-synt_B PF00430.13 ETO35887.1 - 1.5 8.5 10.3 3 7.6 7.1 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) bZIP_2 PF07716.10 ETO35887.1 - 3.5 7.5 7.5 3.4 7.5 1.0 2.7 1 1 1 2 2 2 0 Basic region leucine zipper Syntaxin-6_N PF09177.6 ETO35887.1 - 6 7.3 8.3 28 5.2 1.4 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal HSP70 PF00012.15 ETO35887.1 - 6.7 4.4 9.3 8.9 4.0 6.5 1.1 1 0 0 1 1 1 0 Hsp70 protein XK-related PF09815.4 ETO35888.1 - 0.00089 18.3 0.5 0.0014 17.7 0.4 1.2 1 0 0 1 1 1 1 XK-related protein Androgen_recep PF02166.11 ETO35888.1 - 0.51 9.1 1.6 0.7 8.7 1.1 1.1 1 0 0 1 1 1 0 Androgen receptor Syntaxin_2 PF14523.1 ETO35889.1 - 0.015 15.3 6.1 0.033 14.1 2.7 2.4 2 0 0 2 2 2 0 Syntaxin-like protein DUF2400 PF09674.5 ETO35889.1 - 0.021 14.5 6.0 0.026 14.2 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF2408 PF10303.4 ETO35889.1 - 0.1 12.7 5.3 0.046 13.8 2.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) DUF948 PF06103.6 ETO35889.1 - 0.21 11.4 5.3 3 7.7 0.1 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Rho_Binding PF08912.6 ETO35889.1 - 3 8.2 11.9 0.22 11.8 3.3 2.3 1 1 1 2 2 2 0 Rho Binding DUF4473 PF14747.1 ETO35889.1 - 6.6 7.0 10.4 0.56 10.4 1.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4473) U-box PF04564.10 ETO35890.1 - 3.8e-12 45.9 0.0 2.2e-11 43.5 0.0 2.5 1 0 0 1 1 1 1 U-box domain Kelch_1 PF01344.20 ETO35890.1 - 0.026 14.0 2.1 4 7.0 0.1 3.5 3 0 0 3 3 3 0 Kelch motif Kelch_6 PF13964.1 ETO35890.1 - 0.044 13.9 5.8 9.8 6.5 0.0 4.5 3 2 1 4 4 4 0 Kelch motif DUF948 PF06103.6 ETO35890.1 - 0.71 9.7 3.8 0.78 9.6 0.5 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) WD40 PF00400.27 ETO35891.1 - 2.3e-19 68.4 8.7 1.6e-08 34.1 0.9 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO35891.1 - 9.8e-06 23.9 1.4 0.00015 20.0 0.3 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO35891.1 - 0.032 12.9 1.4 0.12 11.0 0.2 1.9 1 1 1 2 2 2 0 Nup133 N terminal like Med1 PF10744.4 ETO35892.1 - 0.014 14.2 4.7 0.016 13.9 3.2 1.1 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription subunit 1 BAF1_ABF1 PF04684.8 ETO35892.1 - 0.033 13.0 7.2 0.042 12.6 5.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Dicty_REP PF05086.7 ETO35892.1 - 0.15 9.7 10.6 0.17 9.6 7.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Serinc PF03348.10 ETO35892.1 - 0.41 9.2 4.3 0.49 9.0 3.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF3533 PF12051.3 ETO35892.1 - 4.3 5.9 9.5 5.5 5.6 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Mg_trans_NIPA PF05653.9 ETO35893.1 - 5.1e-05 22.3 0.6 0.0064 15.4 0.0 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA Daxx PF03344.10 ETO35893.1 - 0.14 10.6 13.6 0.18 10.2 9.4 1.1 1 0 0 1 1 1 0 Daxx Family DUF1779 PF08680.5 ETO35893.1 - 0.19 11.5 2.9 0.36 10.6 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1779) XhoI PF04555.8 ETO35894.1 - 0.012 15.0 0.0 0.067 12.5 0.0 1.9 1 1 1 2 2 2 0 Restriction endonuclease XhoI DUF4570 PF15134.1 ETO35895.1 - 0.017 14.9 0.2 0.035 13.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) FlgN PF05130.7 ETO35895.1 - 0.043 14.0 0.0 0.073 13.3 0.0 1.4 1 1 0 1 1 1 0 FlgN protein DXP_synthase_N PF13292.1 ETO35895.1 - 0.087 11.7 0.2 0.15 10.9 0.1 1.5 1 1 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase bZIP_1 PF00170.16 ETO35895.1 - 0.23 11.4 4.0 12 5.9 0.0 2.4 2 0 0 2 2 2 0 bZIP transcription factor DUF2935 PF11155.3 ETO35896.1 - 0.061 13.4 11.0 0.087 12.9 7.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) NPV_P10 PF05531.7 ETO35896.1 - 0.39 11.0 12.5 11 6.3 7.6 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SDH_alpha PF03313.10 ETO35896.1 - 0.63 9.0 1.9 0.84 8.6 1.3 1.2 1 0 0 1 1 1 0 Serine dehydratase alpha chain AAA_23 PF13476.1 ETO35896.1 - 0.81 9.9 23.8 1.1 9.4 16.5 1.2 1 0 0 1 1 1 0 AAA domain Cob_adeno_trans PF01923.13 ETO35896.1 - 1.7 8.4 8.0 1.6 8.5 0.6 1.8 1 1 1 2 2 2 0 Cobalamin adenosyltransferase CENP-Q PF13094.1 ETO35896.1 - 1.8 8.5 22.1 1.3 8.9 8.9 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Exonuc_VII_L PF02601.10 ETO35896.1 - 2.3 7.3 17.6 3.2 6.8 12.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit IFT46_B_C PF12317.3 ETO35896.1 - 4.2 6.6 11.4 2.6 7.3 6.5 1.6 1 1 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal MitMem_reg PF13012.1 ETO35896.1 - 6.1 6.9 16.9 30 4.7 11.7 2.0 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function TPR_12 PF13424.1 ETO35897.1 - 6.9e-87 285.4 31.6 8.5e-24 83.2 0.4 5.1 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETO35897.1 - 2.1e-55 183.1 0.9 4.2e-08 32.8 0.0 8.1 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_1 PF00515.23 ETO35897.1 - 2.2e-51 169.4 56.3 2e-08 33.4 1.2 8.1 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_11 PF13414.1 ETO35897.1 - 1.7e-49 165.3 37.1 2.3e-16 59.2 2.3 5.6 4 2 1 5 5 5 5 TPR repeat TPR_2 PF07719.12 ETO35897.1 - 6.4e-41 134.9 42.3 1.5e-06 27.6 0.4 8.1 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_7 PF13176.1 ETO35897.1 - 6.2e-38 125.6 14.3 4.5e-05 22.9 0.0 8.2 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_8 PF13181.1 ETO35897.1 - 2.4e-31 105.1 56.9 2.6e-05 23.6 1.5 8.2 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_16 PF13432.1 ETO35897.1 - 4.7e-24 84.4 3.4 1.3e-05 25.7 0.0 5.2 2 1 4 6 6 6 6 Tetratricopeptide repeat TPR_6 PF13174.1 ETO35897.1 - 3.9e-18 64.5 11.6 0.035 14.5 0.0 8.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO35897.1 - 4.7e-18 64.0 0.0 0.32 11.7 0.0 8.0 6 1 2 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETO35897.1 - 8.4e-16 56.7 33.6 0.0025 17.8 0.7 8.6 6 3 1 7 7 7 5 Tetratricopeptide repeat SNAP PF14938.1 ETO35897.1 - 5.9e-14 51.8 22.4 1e-07 31.4 4.2 3.8 1 1 2 3 3 3 3 Soluble NSF attachment protein, SNAP SHNi-TPR PF10516.4 ETO35897.1 - 4.1e-12 45.1 0.0 1.7 7.9 0.0 6.7 7 0 0 7 7 7 4 SHNi-TPR Apc3 PF12895.2 ETO35897.1 - 2e-11 43.8 26.2 0.00047 20.2 2.3 5.3 1 1 5 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO35897.1 - 3.1e-11 43.4 5.7 0.0022 18.2 0.0 5.2 4 1 2 6 6 6 2 Tetratricopeptide repeat MIT PF04212.13 ETO35897.1 - 6.4e-10 38.7 31.8 0.0055 16.5 0.2 7.8 6 2 2 8 8 8 4 MIT (microtubule interacting and transport) domain DUF2225 PF09986.4 ETO35897.1 - 1.5e-09 37.6 24.6 0.00033 20.2 0.8 4.2 1 1 2 4 4 4 3 Uncharacterized protein conserved in bacteria (DUF2225) TPR_5 PF12688.2 ETO35897.1 - 5.6e-07 29.6 1.4 0.031 14.3 0.1 4.5 3 2 2 5 5 5 2 Tetratrico peptide repeat RPN7 PF10602.4 ETO35897.1 - 1.6e-05 24.3 14.4 0.00037 19.9 0.4 4.5 2 2 2 4 4 4 2 26S proteasome subunit RPN7 Sel1 PF08238.7 ETO35897.1 - 4.7e-05 23.8 26.2 0.11 13.1 0.1 7.8 8 0 0 8 8 8 2 Sel1 repeat PPR PF01535.15 ETO35897.1 - 0.0014 18.4 7.3 9.5 6.4 0.0 6.2 8 0 0 8 8 6 0 PPR repeat DUF627 PF04781.7 ETO35897.1 - 0.0019 17.8 8.6 1.3 8.6 0.1 5.1 3 2 3 6 6 6 2 Protein of unknown function (DUF627) TPR_3 PF07720.7 ETO35897.1 - 0.0028 17.4 28.8 0.098 12.4 0.3 6.0 6 0 0 6 6 5 3 Tetratricopeptide repeat ATP-synt_E_2 PF08112.6 ETO35897.1 - 0.049 13.6 1.4 32 4.6 0.1 4.1 4 0 0 4 4 4 0 ATP synthase epsilon subunit OEP PF02321.13 ETO35897.1 - 0.18 11.3 11.9 4.6 6.7 5.3 3.1 2 1 0 2 2 2 0 Outer membrane efflux protein TPR_12 PF13424.1 ETO35898.1 - 2e-41 139.7 1.8 1.2e-22 79.6 0.0 3.5 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO35898.1 - 4.8e-23 80.5 12.6 1.3e-10 40.7 0.5 4.3 3 1 1 4 4 4 4 TPR repeat TPR_10 PF13374.1 ETO35898.1 - 4.1e-22 77.3 0.0 0.0001 22.1 0.0 4.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETO35898.1 - 3.6e-20 70.6 22.4 7.1e-07 28.5 0.4 4.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO35898.1 - 1.1e-18 65.5 26.7 8.9e-06 25.1 0.9 5.0 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO35898.1 - 2.8e-18 64.2 14.2 5.1e-06 26.0 0.1 4.8 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO35898.1 - 4.8e-17 60.3 3.1 2.7e-05 23.6 0.1 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETO35898.1 - 1.9e-07 30.6 7.7 0.3 11.3 0.0 5.2 6 0 0 6 6 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO35898.1 - 4.8e-07 30.2 0.0 0.25 12.0 0.0 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETO35898.1 - 1.3e-06 28.5 0.0 0.82 10.4 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO35898.1 - 6.1e-06 26.3 1.3 0.34 11.4 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat MIT PF04212.13 ETO35898.1 - 2.1e-05 24.3 7.4 0.24 11.3 0.3 4.1 4 0 0 4 4 4 2 MIT (microtubule interacting and transport) domain DUF2225 PF09986.4 ETO35898.1 - 4.5e-05 23.0 4.4 0.00024 20.6 0.9 2.4 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) Apc3 PF12895.2 ETO35898.1 - 0.00029 20.8 10.8 0.0081 16.2 1.2 3.7 1 1 3 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 DUF627 PF04781.7 ETO35898.1 - 0.016 14.8 4.6 7 6.3 0.0 4.4 3 1 2 5 5 5 0 Protein of unknown function (DUF627) PPR PF01535.15 ETO35898.1 - 0.045 13.7 8.2 0.098 12.6 0.0 4.5 5 0 0 5 5 5 0 PPR repeat SMI1_KNR4 PF09346.5 ETO35899.1 - 1.2 9.1 6.9 0.82 9.6 0.9 2.5 1 1 1 2 2 2 0 SMI1 / KNR4 family (SUKH-1) TPR_12 PF13424.1 ETO35900.1 - 1.5e-31 108.1 6.0 2.7e-16 59.2 1.9 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO35900.1 - 1.3e-16 59.0 6.7 0.00023 20.7 0.0 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO35900.1 - 2e-16 59.4 21.7 4.2e-09 35.9 2.1 4.0 1 1 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 ETO35900.1 - 4.6e-14 51.3 21.3 1e-05 24.9 0.8 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO35900.1 - 1.3e-13 49.6 16.8 0.0076 16.0 0.4 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO35900.1 - 7.1e-12 44.8 0.0 0.0023 17.7 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO35900.1 - 4.2e-06 26.1 19.3 0.011 15.4 0.4 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO35900.1 - 0.0054 16.8 1.9 4.2 7.8 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat zf-UBP PF02148.14 ETO35900.1 - 0.0094 16.0 0.9 0.03 14.4 0.3 2.1 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein TPR_6 PF13174.1 ETO35900.1 - 0.016 15.5 2.9 56 4.5 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETO35900.1 - 0.019 15.5 0.0 32 5.5 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO35900.1 - 0.019 14.2 1.2 0.21 10.8 0.1 2.9 3 0 0 3 3 3 0 SHNi-TPR MIT PF04212.13 ETO35900.1 - 0.14 12.0 9.6 5 7.0 0.5 4.2 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain BCAS2 PF05700.6 ETO35900.1 - 0.22 10.9 5.3 5.3 6.4 0.8 2.4 2 0 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) Kelch_6 PF13964.1 ETO35901.1 - 1.4e-10 40.8 3.4 1.7e-05 24.7 0.0 4.6 4 1 1 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO35901.1 - 3.4e-07 29.9 0.2 0.00062 19.4 0.0 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO35901.1 - 9.3e-06 25.2 0.9 0.0074 16.0 0.0 4.4 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 ETO35901.1 - 0.00022 20.6 1.4 1.4 8.4 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO35901.1 - 0.00079 19.5 0.7 0.0078 16.3 0.0 3.0 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO35901.1 - 0.00099 19.0 4.1 0.24 11.4 0.1 4.1 5 0 0 5 5 5 1 Kelch motif WD40 PF00400.27 ETO35903.1 - 8.6e-24 82.5 14.7 7.2e-09 35.1 0.2 5.7 5 1 0 5 5 5 5 WD domain, G-beta repeat Pacifastin_I PF05375.8 ETO35903.1 - 1.2 8.6 7.6 0.055 12.9 1.0 1.9 2 0 0 2 2 2 0 Pacifastin inhibitor (LCMII) Pkinase PF00069.20 ETO35905.1 - 1.1e-55 188.6 3.0 1.3e-55 188.3 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO35905.1 - 4e-21 75.2 0.0 1.7e-13 50.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase cNMP_binding PF00027.24 ETO35905.1 - 1.5e-10 40.6 0.0 1.8e-06 27.6 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DUF1856 PF08983.5 ETO35908.1 - 0.38 10.8 0.1 0.38 10.8 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1856) WD40 PF00400.27 ETO35910.1 - 2.9e-43 144.2 21.4 1.2e-10 40.8 0.7 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO35910.1 - 1.4e-08 33.3 5.3 0.12 10.4 0.1 4.7 2 2 2 4 4 4 4 Nucleoporin Nup120/160 HAD PF12710.2 ETO35910.1 - 0.04 14.0 2.4 2.2 8.4 0.0 3.0 1 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Kelch_1 PF01344.20 ETO35911.1 - 5.7e-06 25.7 1.3 0.0048 16.4 0.3 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 ETO35911.1 - 8.9e-06 25.6 2.5 0.14 12.3 0.3 3.7 2 1 1 3 3 3 2 Kelch motif Kelch_5 PF13854.1 ETO35911.1 - 1.3e-05 24.9 0.8 1.4 8.9 0.1 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.1 ETO35911.1 - 0.00086 19.4 0.7 0.014 15.4 0.1 3.0 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO35911.1 - 0.0011 18.5 4.6 0.3 10.9 0.1 4.2 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO35911.1 - 0.0021 17.8 3.1 0.44 10.3 0.2 3.0 3 0 0 3 3 3 2 Galactose oxidase, central domain Macoilin PF09726.4 ETO35912.1 - 0.019 13.2 6.1 0.021 13.1 4.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Tom22 PF04281.8 ETO35912.1 - 0.098 12.1 8.7 0.13 11.7 5.7 1.3 1 1 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DnaA_N PF11638.3 ETO35912.1 - 0.37 10.3 2.0 24 4.5 0.0 2.7 2 1 1 3 3 3 0 DnaA N-terminal domain DUF1640 PF07798.6 ETO35912.1 - 0.47 10.4 9.6 2 8.4 3.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) SecD-TM1 PF13721.1 ETO35912.1 - 0.73 10.1 3.7 0.6 10.3 1.0 1.9 2 0 0 2 2 2 0 SecD export protein N-terminal TM region OmpH PF03938.9 ETO35912.1 - 0.79 9.6 14.2 1 9.2 9.8 1.0 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) UPF0242 PF06785.6 ETO35912.1 - 1 7.9 6.8 1.1 7.8 4.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) DUF4600 PF15372.1 ETO35912.1 - 1.3 9.2 11.6 16 5.7 8.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) V_ATPase_I PF01496.14 ETO35912.1 - 1.4 6.6 9.0 1.6 6.5 6.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HSCB_C PF07743.8 ETO35912.1 - 1.4 9.3 9.4 0.55 10.7 3.6 2.0 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain K-box PF01486.12 ETO35912.1 - 3.7 7.4 11.6 44 3.9 7.3 2.9 1 1 1 2 2 2 0 K-box region Bap31 PF05529.7 ETO35912.1 - 5.7 6.3 12.5 9.7 5.6 8.6 1.4 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like COX16 PF14138.1 ETO35912.1 - 7.7 6.7 9.5 11 6.2 0.3 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein COX16 IncA PF04156.9 ETO35912.1 - 8.1 5.9 8.2 10 5.6 5.7 1.2 1 0 0 1 1 1 0 IncA protein Nuc-transf PF10127.4 ETO35913.1 - 1.9e-22 79.8 0.0 3.2e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Predicted nucleotidyltransferase DUF3844 PF12955.2 ETO35914.1 - 0.011 15.8 0.1 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) N_methyl_2 PF13544.1 ETO35915.1 - 2.4e-06 26.7 0.3 7.5e-06 25.1 0.2 1.9 1 0 0 1 1 1 1 Type IV pilin N-term methylation site GFxxxE N_methyl PF07963.7 ETO35915.1 - 0.02 14.6 9.3 0.061 13.1 6.4 1.9 1 1 0 1 1 1 0 Prokaryotic N-terminal methylation motif DUF1049 PF06305.6 ETO35915.1 - 0.066 12.6 0.7 0.13 11.7 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) CcmD PF04995.9 ETO35915.1 - 0.27 10.9 0.9 0.37 10.5 0.1 1.5 1 1 1 2 2 2 0 Heme exporter protein D (CcmD) TadE PF07811.7 ETO35915.1 - 1.8 8.5 4.5 3.6 7.5 3.1 1.5 1 0 0 1 1 1 0 TadE-like protein N_methyl_3 PF13633.1 ETO35915.1 - 3.2 7.8 15.0 0.66 9.9 7.7 2.1 2 0 0 2 2 2 0 Prokaryotic N-terminal methylation site BTB PF00651.26 ETO35918.1 - 3.1e-06 27.1 0.5 7.7e-06 25.8 0.1 1.8 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.10 ETO35918.1 - 0.00042 20.1 0.5 0.019 14.8 0.1 2.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch Sigma54_AID PF00309.15 ETO35918.1 - 0.34 10.3 1.6 0.4 10.1 0.3 1.7 2 0 0 2 2 2 0 Sigma-54 factor, Activator interacting domain (AID) DUF2683 PF10884.3 ETO35919.1 - 0.036 13.9 0.0 0.089 12.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2683) Cortexin PF11057.3 ETO35919.1 - 0.037 13.6 0.0 0.077 12.6 0.0 1.6 1 0 0 1 1 1 0 Cortexin of kidney DUF3948 PF13134.1 ETO35919.1 - 0.22 11.0 2.9 0.42 10.1 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3948) CDC45 PF02724.9 ETO35920.1 - 0.014 13.4 11.3 0.017 13.2 7.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.12 ETO35920.1 - 0.087 12.6 13.2 0.0079 16.0 6.2 1.6 2 0 0 2 2 2 0 DDHD domain TP53IP5 PF15331.1 ETO35920.1 - 0.4 10.5 14.7 0.024 14.5 6.5 1.7 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 DUF2201_N PF13203.1 ETO35920.1 - 0.47 9.5 11.4 0.65 9.1 7.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain LMBR1 PF04791.11 ETO35920.1 - 0.9 8.0 6.0 1.3 7.5 4.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4175 PF13779.1 ETO35920.1 - 3.2 5.3 16.7 4.2 4.9 11.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Mem_trans PF03547.13 ETO35920.1 - 3.4 5.8 6.7 4.4 5.4 4.7 1.2 1 0 0 1 1 1 0 Membrane transport protein GvpL_GvpF PF06386.6 ETO35920.1 - 3.7 7.0 11.6 6.4 6.2 8.0 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Presenilin PF01080.12 ETO35920.1 - 9.4 4.9 13.7 17 4.1 9.5 1.4 1 0 0 1 1 1 0 Presenilin TPR_12 PF13424.1 ETO35921.1 - 8.2e-38 128.2 4.6 5.4e-22 77.5 0.6 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO35921.1 - 8.5e-22 76.5 12.9 1.6e-13 50.1 0.7 3.1 1 1 2 3 3 3 3 TPR repeat TPR_10 PF13374.1 ETO35921.1 - 9.1e-21 73.1 0.1 7.5e-10 38.4 0.0 3.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO35921.1 - 8.3e-20 68.9 4.2 1.1e-08 34.1 0.0 3.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO35921.1 - 2.1e-19 68.2 15.2 2.3e-09 36.4 0.3 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO35921.1 - 6.5e-16 56.9 9.3 3.6e-05 23.3 0.1 4.2 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO35921.1 - 3.7e-12 45.1 18.5 3.9e-06 26.2 0.9 3.6 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO35921.1 - 1.9e-09 36.9 2.7 9.9e-05 22.2 0.9 3.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO35921.1 - 3.9e-08 33.7 0.1 0.0012 19.4 0.0 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_3 PF07720.7 ETO35921.1 - 1.7e-06 27.6 8.3 0.019 14.7 0.1 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 ETO35921.1 - 9.5e-06 25.6 3.1 0.00086 19.4 1.5 2.9 1 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO35921.1 - 0.00014 22.1 0.7 0.085 13.2 0.4 3.1 1 1 1 2 2 2 1 Tetratricopeptide repeat SNAP PF14938.1 ETO35921.1 - 0.00071 18.8 0.9 0.0013 17.9 0.7 1.3 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.1 ETO35921.1 - 0.00093 19.5 1.2 11 6.7 0.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETO35921.1 - 0.0016 18.9 0.0 10 7.0 0.0 3.8 2 2 2 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.4 ETO35921.1 - 0.0025 17.2 1.4 0.7 9.2 0.1 2.4 1 1 1 2 2 2 2 26S proteasome subunit RPN7 PPR PF01535.15 ETO35921.1 - 0.0054 16.6 4.3 3.6 7.7 0.0 4.2 5 0 0 5 5 4 1 PPR repeat Sel1 PF08238.7 ETO35921.1 - 0.032 14.8 3.2 47 4.8 0.0 4.1 3 1 1 4 4 4 0 Sel1 repeat Pep3_Vps18 PF05131.9 ETO35921.1 - 0.058 12.8 0.3 7.7 5.9 0.0 3.0 3 0 0 3 3 3 0 Pep3/Vps18/deep orange family DUF627 PF04781.7 ETO35921.1 - 0.062 12.9 0.8 1.5 8.5 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF627) MIT PF04212.13 ETO35921.1 - 0.25 11.2 9.5 0.82 9.5 0.6 3.3 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain ATP-synt_E_2 PF08112.6 ETO35921.1 - 0.78 9.8 3.9 11 6.1 0.1 2.4 2 0 0 2 2 2 0 ATP synthase epsilon subunit TPR_12 PF13424.1 ETO35922.1 - 9.7e-08 31.8 0.0 1.4e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO35922.1 - 0.014 15.1 1.7 0.017 14.8 0.4 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETO35922.1 - 0.018 14.6 1.2 0.028 14.0 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETO35922.1 - 0.024 14.5 0.1 0.052 13.4 0.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 ETO35922.1 - 0.036 13.7 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 TPR repeat TPR_21 PF09976.4 ETO35922.1 - 0.082 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat RNase_H PF00075.19 ETO35924.1 - 0.038 14.3 0.0 0.084 13.2 0.0 1.6 1 0 0 1 1 1 0 RNase H AbbA_antirepres PF14156.1 ETO35925.1 - 0.015 14.9 5.4 0.051 13.2 1.9 2.8 3 0 0 3 3 3 0 Antirepressor AbbA FliP PF00813.15 ETO35925.1 - 0.29 10.8 1.0 0.95 9.1 0.7 1.9 1 0 0 1 1 1 0 FliP family Frataxin_Cyay PF01491.11 ETO35926.1 - 6.5e-10 38.7 1.2 1.6e-09 37.4 0.9 1.7 1 1 0 1 1 1 1 Frataxin-like domain Protocadherin PF08374.6 ETO35927.1 - 0.059 12.9 0.6 0.066 12.8 0.4 1.1 1 0 0 1 1 1 0 Protocadherin DUF2179 PF10035.4 ETO35927.1 - 0.087 12.4 0.1 0.35 10.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2179) Intg_mem_TP0381 PF09529.5 ETO35927.1 - 3.4 6.8 6.1 8.3 5.5 4.3 1.6 1 1 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) RRM_1 PF00076.17 ETO35929.1 - 1.3e-18 66.4 0.0 1.9e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO35929.1 - 4.4e-11 42.6 0.0 6.8e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO35929.1 - 4.1e-09 36.1 0.0 6.2e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ILVD_EDD PF00920.16 ETO35930.1 - 2.6e-36 125.1 0.1 3.3e-34 118.2 0.1 2.1 1 1 0 1 1 1 1 Dehydratase family ILVD_EDD PF00920.16 ETO35931.1 - 2.1e-114 382.8 0.0 2.4e-114 382.6 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family rve PF00665.21 ETO35932.1 - 1.1e-21 77.1 0.0 1.6e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 ETO35932.1 - 0.0075 15.7 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 ETO35933.1 - 3.5e-15 55.9 0.9 1.2e-13 50.9 0.1 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Duffy_binding PF05424.6 ETO35933.1 - 0.16 11.7 7.5 1.7 8.4 0.9 2.5 2 1 0 2 2 2 0 Duffy binding domain Fucose_iso_C PF02952.12 ETO35934.1 - 0.061 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 L-fucose isomerase, C-terminal domain COLFI PF01410.13 ETO35935.1 - 1.2 8.5 5.7 0.11 11.8 0.4 1.7 2 0 0 2 2 2 0 Fibrillar collagen C-terminal domain F5_F8_type_C PF00754.20 ETO35938.1 - 9e-06 25.5 6.2 0.0032 17.3 0.5 2.7 2 1 0 2 2 2 2 F5/8 type C domain Sad1_UNC PF07738.8 ETO35938.1 - 1.4e-05 24.9 1.2 0.052 13.3 0.1 2.3 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal Oligomerisation PF02410.10 ETO35938.1 - 0.041 13.9 1.2 7 6.7 0.0 3.3 3 0 0 3 3 3 0 Oligomerisation domain DUF2399 PF09664.5 ETO35938.1 - 0.091 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) zf-RING_2 PF13639.1 ETO35939.1 - 4e-08 32.9 3.1 4e-08 32.9 2.1 4.9 6 1 0 6 6 6 1 Ring finger domain F5_F8_type_C PF00754.20 ETO35939.1 - 1.5e-06 28.0 1.5 0.001 18.8 0.2 2.3 2 0 0 2 2 2 2 F5/8 type C domain zf-C3HC4 PF00097.20 ETO35939.1 - 0.0024 17.4 6.1 0.0024 17.4 4.2 5.4 7 1 0 7 7 7 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETO35939.1 - 0.0077 16.3 7.1 0.0077 16.3 4.9 4.5 4 2 1 5 5 5 1 RING-H2 zinc finger DUF2457 PF10446.4 ETO35940.1 - 2.6e-06 26.4 24.5 2.8e-06 26.3 17.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) CDC45 PF02724.9 ETO35940.1 - 6.3e-05 21.2 16.9 7.5e-05 20.9 11.7 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.7 ETO35940.1 - 0.0012 16.8 30.5 0.0016 16.5 21.2 1.1 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 ETO35940.1 - 0.0028 16.2 24.7 0.0034 15.9 17.1 1.1 1 0 0 1 1 1 1 Daxx Family DUF572 PF04502.8 ETO35940.1 - 0.011 14.9 13.3 0.014 14.6 9.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF1510 PF07423.6 ETO35940.1 - 0.032 13.6 22.7 0.044 13.1 15.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Paf1 PF03985.8 ETO35940.1 - 0.04 12.6 20.0 0.062 12.0 13.8 1.4 1 0 0 1 1 1 0 Paf1 CENP-T PF15511.1 ETO35940.1 - 0.11 11.7 14.1 0.13 11.4 9.8 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T YL1 PF05764.8 ETO35940.1 - 0.15 11.6 18.6 0.21 11.1 12.9 1.3 1 0 0 1 1 1 0 YL1 nuclear protein ABC2_membrane_3 PF12698.2 ETO35940.1 - 0.17 10.9 5.7 0.24 10.4 4.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein BUD22 PF09073.5 ETO35940.1 - 0.17 10.9 21.9 0.21 10.6 15.2 1.1 1 0 0 1 1 1 0 BUD22 Prog_receptor PF02161.10 ETO35940.1 - 0.2 10.4 3.8 0.21 10.4 2.6 1.1 1 0 0 1 1 1 0 Progesterone receptor SDA1 PF05285.7 ETO35940.1 - 0.38 10.0 28.2 0.48 9.6 19.5 1.1 1 0 0 1 1 1 0 SDA1 VID27 PF08553.5 ETO35940.1 - 0.47 8.6 22.2 0.55 8.4 15.4 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein Utp14 PF04615.8 ETO35940.1 - 0.72 7.9 22.4 0.85 7.7 15.5 1.0 1 0 0 1 1 1 0 Utp14 protein Vfa1 PF08432.5 ETO35940.1 - 0.83 9.6 17.3 1.2 9.1 12.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CCDC84 PF14968.1 ETO35940.1 - 0.95 8.8 10.2 1.3 8.4 7.1 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 DUF2890 PF11081.3 ETO35940.1 - 1.7 8.6 14.0 2.5 8.1 9.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Drc1-Sld2 PF11719.3 ETO35940.1 - 2.1 7.3 16.0 2.6 7.0 11.1 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein eIF-3c_N PF05470.7 ETO35940.1 - 2.3 6.1 17.6 3 5.8 12.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Zip PF02535.17 ETO35940.1 - 3.8 6.4 7.7 0.59 9.0 2.3 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter RRN3 PF05327.6 ETO35940.1 - 4.1 5.4 14.8 5 5.1 10.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Peptidase_S64 PF08192.6 ETO35940.1 - 8.9 4.5 12.5 11 4.2 8.7 1.2 1 0 0 1 1 1 0 Peptidase family S64 Fe-ADH PF00465.14 ETO35941.1 - 7.1e-18 64.3 0.0 1.1e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase RFC1 PF08519.7 ETO35941.1 - 0.009 15.7 0.1 0.023 14.4 0.1 1.8 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain DUF4285 PF14113.1 ETO35941.1 - 0.1 12.6 0.2 0.3 11.0 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4285) DUF4168 PF13767.1 ETO35941.1 - 1.4 9.5 5.9 16 6.2 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4168) DUF3853 PF12964.2 ETO35942.1 - 0.11 12.3 0.0 0.33 10.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) Tetraspannin PF00335.15 ETO35943.1 - 0.081 12.1 0.1 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Tetraspanin family DUF3439 PF11921.3 ETO35944.1 - 2.1 8.0 10.1 7.2 6.3 7.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SCP2 PF02036.12 ETO35945.1 - 5.2e-18 65.2 0.1 9.1e-18 64.4 0.1 1.4 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 ETO35945.1 - 0.0012 18.8 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal PhzC-PhzF PF02567.11 ETO35946.1 - 9.6e-49 166.0 0.0 1.1e-48 165.8 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein CholecysA-Rec_N PF09193.5 ETO35946.1 - 0.009 15.8 0.3 0.027 14.3 0.1 1.8 2 0 0 2 2 2 1 Cholecystokinin A receptor, N-terminal PH_8 PF15409.1 ETO35947.1 - 5.9e-10 39.0 0.1 1.1e-09 38.2 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 ETO35947.1 - 8.8e-09 35.5 4.0 1.5e-08 34.7 0.4 2.3 2 1 0 2 2 2 1 PH domain PH_3 PF14593.1 ETO35947.1 - 1.1e-07 31.6 0.1 2.2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 ETO35947.1 - 1.9e-05 24.9 2.1 0.009 16.2 0.3 2.5 1 1 1 2 2 2 2 Pleckstrin homology domain WTX PF09422.5 ETO35947.1 - 0.16 10.9 6.3 0.2 10.5 4.4 1.1 1 0 0 1 1 1 0 WTX protein WD40 PF00400.27 ETO35950.1 - 0.0001 22.0 2.5 0.019 14.8 0.3 3.4 3 2 0 3 3 3 2 WD domain, G-beta repeat WD40 PF00400.27 ETO35952.1 - 9.3e-05 22.1 0.2 0.00039 20.1 0.2 1.8 2 0 0 2 2 2 1 WD domain, G-beta repeat Orthoreo_P17 PF07272.6 ETO35953.1 - 0.017 14.9 0.3 4.4 7.0 0.3 2.2 2 1 0 2 2 2 0 Orthoreovirus P17 protein Fibrillarin PF01269.12 ETO35953.1 - 0.035 13.0 0.7 0.041 12.8 0.5 1.1 1 0 0 1 1 1 0 Fibrillarin Stork_head PF10264.4 ETO35953.1 - 0.047 13.8 0.1 0.1 12.7 0.1 1.6 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain BsuBI_PstI_RE PF06616.6 ETO35953.1 - 0.097 11.4 0.2 0.15 10.8 0.1 1.2 1 1 0 1 1 1 0 BsuBI/PstI restriction endonuclease C-terminus WD40 PF00400.27 ETO35954.1 - 1.6e-154 496.9 39.0 8.2e-12 44.5 0.3 16.3 16 0 0 16 16 16 15 WD domain, G-beta repeat Nup160 PF11715.3 ETO35954.1 - 2.7e-19 68.7 24.9 0.05 11.7 0.3 13.8 1 1 11 13 13 13 12 Nucleoporin Nup120/160 PD40 PF07676.7 ETO35954.1 - 1.9e-06 27.4 13.0 2.8 7.7 0.0 8.1 9 0 0 9 9 9 3 WD40-like Beta Propeller Repeat Pentapeptide PF00805.17 ETO35954.1 - 1.5e-05 24.1 1.0 3e-05 23.1 0.7 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO35954.1 - 5e-05 23.0 0.3 0.00015 21.4 0.2 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 ETO35954.1 - 0.00035 20.4 0.6 0.0015 18.3 0.5 2.2 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) F420_ligase PF01996.11 ETO35954.1 - 0.038 13.0 0.0 1.4 7.9 0.0 3.0 2 1 0 2 2 2 0 F420-0:Gamma-glutamyl ligase DUF1938 PF09153.5 ETO35954.1 - 0.066 13.0 4.4 1.9 8.3 0.2 4.8 4 2 2 6 6 6 0 Domain of unknown function (DUF1938) WD40 PF00400.27 ETO35955.1 - 2e-30 103.5 10.6 2e-08 33.7 0.0 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO35955.1 - 4.7e-12 44.8 3.6 2.1e-05 22.9 0.1 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 WD40 PF00400.27 ETO35956.1 - 1.9e-147 474.5 45.7 1.5e-11 43.6 0.1 16.5 16 0 0 16 16 16 15 WD domain, G-beta repeat NACHT PF05729.7 ETO35956.1 - 9.2e-11 41.6 0.0 2.1e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.7 ETO35956.1 - 4.5e-07 29.3 12.9 0.005 16.4 0.0 7.8 8 0 0 8 8 8 1 WD40-like Beta Propeller Repeat Pentapeptide PF00805.17 ETO35956.1 - 2.2e-06 26.7 0.3 4.1e-06 25.9 0.2 1.4 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) AAA_18 PF13238.1 ETO35956.1 - 9.4e-06 25.9 2.0 2.6e-05 24.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain PQQ_2 PF13360.1 ETO35956.1 - 1.3e-05 24.7 0.2 0.2 11.0 0.0 4.1 2 2 0 2 2 2 2 PQQ-like domain Pentapeptide_4 PF13599.1 ETO35956.1 - 2.3e-05 24.0 0.2 6.3e-05 22.6 0.2 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 ETO35956.1 - 0.00027 20.7 1.0 0.00082 19.2 0.7 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA_17 PF13207.1 ETO35956.1 - 0.0018 19.0 0.1 0.015 16.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETO35956.1 - 0.0029 17.7 0.0 0.0088 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 ETO35956.1 - 0.0043 16.2 0.4 0.87 8.6 0.0 2.6 2 0 0 2 2 2 1 KaiC F420_ligase PF01996.11 ETO35956.1 - 0.063 12.3 0.0 0.93 8.5 0.0 2.9 4 0 0 4 4 4 0 F420-0:Gamma-glutamyl ligase FtsK_SpoIIIE PF01580.13 ETO35956.1 - 0.21 11.0 0.0 0.38 10.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Ras PF00071.17 ETO35957.1 - 1e-23 83.5 0.0 1.6e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO35957.1 - 6.5e-13 49.2 0.0 1.4e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO35957.1 - 5.1e-07 29.0 0.0 7.3e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO35957.1 - 0.00044 19.7 0.0 0.0013 18.2 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 ETO35957.1 - 0.025 13.7 0.1 0.025 13.7 0.0 1.5 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region ALMT PF11744.3 ETO35958.1 - 0.021 13.5 0.1 0.022 13.4 0.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Endotoxin_N PF03945.9 ETO35960.1 - 0.009 15.4 0.4 0.014 14.8 0.3 1.2 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain DUF1151 PF06625.6 ETO35960.1 - 0.011 15.5 0.8 0.017 14.8 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) Myb_DNA-bind_4 PF13837.1 ETO35960.1 - 5.3 7.2 6.9 1.4 9.0 1.4 2.1 1 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain AAA PF00004.24 ETO35961.1 - 5.4e-10 39.5 0.0 4.9e-05 23.5 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETO35961.1 - 2.1e-08 34.3 0.0 0.02 15.0 0.0 4.9 4 1 0 4 4 4 2 AAA domain AAA_5 PF07728.9 ETO35961.1 - 4.2e-06 26.5 0.0 0.059 13.0 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 ETO35961.1 - 0.00081 19.6 0.2 0.0063 16.8 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_23 PF13476.1 ETO35961.1 - 0.0014 19.0 0.0 0.0014 19.0 0.0 3.8 2 1 0 3 3 2 1 AAA domain AAA_16 PF13191.1 ETO35961.1 - 0.0022 17.9 0.0 0.32 10.9 0.0 3.5 3 0 0 3 3 3 1 AAA ATPase domain DUF815 PF05673.8 ETO35961.1 - 0.0024 16.8 0.1 0.026 13.4 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF815) DUF258 PF03193.11 ETO35961.1 - 0.0029 16.7 0.1 0.024 13.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NACHT PF05729.7 ETO35961.1 - 0.0055 16.3 5.5 0.44 10.2 0.0 4.6 4 1 0 4 4 4 1 NACHT domain MCM PF00493.18 ETO35961.1 - 0.0073 15.1 0.1 1.8 7.3 0.0 2.5 2 0 0 2 2 2 2 MCM2/3/5 family Sigma54_activ_2 PF14532.1 ETO35961.1 - 0.028 14.4 0.0 0.29 11.1 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain PduV-EutP PF10662.4 ETO35961.1 - 0.045 13.2 0.1 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.1 ETO35961.1 - 0.1 12.3 0.0 15 5.4 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA_25 PF13481.1 ETO35961.1 - 0.21 10.9 0.0 4.1 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.20 ETO35966.1 - 0.013 14.6 0.2 0.02 14.0 0.1 1.4 1 1 0 1 1 1 0 Protein kinase domain Methyltransf_12 PF08242.7 ETO35966.1 - 0.094 13.2 0.7 0.13 12.7 0.5 1.2 1 0 0 1 1 1 0 Methyltransferase domain WD40 PF00400.27 ETO35967.1 - 4.4e-16 58.0 0.6 6e-10 38.6 0.0 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO35967.1 - 0.013 13.6 0.4 1.8 6.6 0.0 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO35967.1 - 0.054 12.2 0.3 0.3 9.7 0.2 1.8 1 1 0 1 1 1 0 Nup133 N terminal like HAD PF12710.2 ETO35967.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.6 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Latarcin PF10279.4 ETO35968.1 - 0.47 10.6 4.6 0.27 11.4 1.2 2.0 2 0 0 2 2 2 0 Latarcin precursor RabGAP-TBC PF00566.13 ETO35969.1 - 2.7e-22 79.3 22.7 2.9e-22 79.1 7.0 3.5 2 0 0 2 2 2 2 Rab-GTPase-TBC domain UPRTase PF14681.1 ETO35969.1 - 4.9e-09 35.6 0.3 8.7e-07 28.3 0.1 2.7 2 1 0 2 2 2 2 Uracil phosphoribosyltransferase Rhodanese PF00581.15 ETO35969.1 - 1.8e-05 25.0 0.0 6.2e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 Rhodanese-like domain CobD_Cbib PF03186.8 ETO35969.1 - 2.1 7.3 4.2 0.97 8.4 0.0 2.1 2 0 0 2 2 2 0 CobD/Cbib protein TPR_12 PF13424.1 ETO35970.1 - 0.03 14.2 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETO35970.1 - 0.2 11.3 0.6 0.31 10.7 0.1 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat GDI PF00996.13 ETO35971.1 - 1.3e-09 36.9 0.0 1.3e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor Peptidase_C14 PF00656.17 ETO35972.1 - 3.6e-11 43.2 0.0 4.5e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Caspase domain DUF3990 PF13151.1 ETO35973.1 - 0.49 9.7 5.3 0.98 8.7 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3990) DUF508 PF04370.7 ETO35974.1 - 0.25 10.9 8.8 0.47 10.0 6.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF508) A2L_zn_ribbon PF08792.5 ETO35974.1 - 0.3 10.5 5.8 7.5 6.1 0.1 3.1 3 0 0 3 3 3 0 A2L zinc ribbon domain Macoilin PF09726.4 ETO35974.1 - 1.9 6.6 22.6 2.8 6.1 15.7 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF4199 PF13858.1 ETO35975.1 - 0.0024 17.8 0.0 0.0076 16.1 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) NICE-3 PF07406.6 ETO35975.1 - 0.045 13.2 0.3 0.64 9.4 0.0 2.6 2 1 1 3 3 3 0 NICE-3 protein WD40 PF00400.27 ETO35977.1 - 1.3e-09 37.5 0.7 3.2e-07 29.9 0.0 2.7 2 1 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO35977.1 - 0.085 10.9 0.0 0.1 10.7 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 TPR_12 PF13424.1 ETO35978.1 - 1.1e-07 31.6 0.0 1.6e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETO35978.1 - 1.9e-06 27.2 2.6 0.0003 20.3 0.6 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO35978.1 - 3e-06 26.7 0.1 5.4e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 TPR repeat TPR_10 PF13374.1 ETO35978.1 - 0.00042 20.1 0.0 0.029 14.2 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO35978.1 - 0.00079 19.0 0.0 0.0024 17.5 0.0 1.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO35978.1 - 0.0019 17.9 0.7 0.32 11.0 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO35978.1 - 0.0038 16.7 1.9 0.0092 15.5 0.6 2.2 2 1 0 2 2 2 1 Tetratricopeptide repeat E1-E2_ATPase PF00122.15 ETO35979.1 - 1.6e-30 105.8 0.1 1.8e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 E1-E2 ATPase RskA PF10099.4 ETO35979.1 - 0.084 12.5 0.2 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Oxidored_q2 PF00420.19 ETO35979.1 - 0.21 11.1 3.0 0.35 10.5 2.1 1.3 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF1469 PF07332.6 ETO35979.1 - 5 6.8 9.1 19 4.9 6.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1469) Hydrolase_like2 PF13246.1 ETO35980.1 - 4e-20 71.5 0.1 5.9e-20 71.0 0.1 1.3 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 ETO35980.1 - 0.00023 21.6 0.0 0.00023 21.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETO35980.1 - 0.0019 18.3 0.0 0.0019 18.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Kelch_5 PF13854.1 ETO35981.1 - 0.0014 18.5 0.0 0.0069 16.3 0.0 2.0 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETO35981.1 - 0.034 14.3 0.9 0.21 11.8 0.1 2.4 2 2 1 3 3 3 0 Kelch motif POLO_box PF00659.13 ETO35981.1 - 0.078 12.9 0.1 0.7 9.9 0.0 2.1 2 0 0 2 2 2 0 POLO box duplicated region Ank_2 PF12796.2 ETO35982.1 - 2.4e-06 27.8 0.2 0.0073 16.6 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETO35982.1 - 0.0023 18.3 1.8 1.2 9.7 0.1 3.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) CobT PF06213.7 ETO35982.1 - 0.016 14.3 4.7 0.024 13.8 2.9 1.6 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Ank PF00023.25 ETO35982.1 - 0.037 13.8 1.6 44 4.1 0.0 4.3 4 0 0 4 4 4 0 Ankyrin repeat Ank_5 PF13857.1 ETO35982.1 - 0.048 13.9 0.2 1.5 9.1 0.0 3.1 2 1 1 3 3 3 0 Ankyrin repeats (many copies) FAM176 PF14851.1 ETO35982.1 - 4.1 7.0 7.3 6.9 6.3 4.0 2.0 2 0 0 2 2 2 0 FAM176 family Nuc_sug_transp PF04142.10 ETO35983.1 - 3.6e-38 131.0 7.5 6.3e-38 130.2 5.2 1.4 1 1 0 1 1 1 1 Nucleotide-sugar transporter Paf67 PF10255.4 ETO35983.1 - 0.017 14.0 0.0 0.023 13.5 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 EamA PF00892.15 ETO35983.1 - 0.085 12.8 16.5 2.1 8.4 7.0 2.5 2 1 0 2 2 2 0 EamA-like transporter family TPT PF03151.11 ETO35983.1 - 0.12 11.9 8.3 2.2 7.8 0.4 2.8 2 1 0 2 2 2 0 Triose-phosphate Transporter family EmrE PF13536.1 ETO35983.1 - 0.75 10.0 11.3 1.1 9.5 0.3 2.6 2 0 0 2 2 2 0 Multidrug resistance efflux transporter Complex1_LYR_2 PF13233.1 ETO35984.1 - 0.17 12.3 0.9 0.32 11.4 0.2 1.9 1 1 0 1 1 1 0 Complex1_LYR-like WD40 PF00400.27 ETO35985.1 - 2e-08 33.7 0.1 9.7e-08 31.6 0.0 1.9 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF4145 PF13643.1 ETO35986.1 - 0.0093 15.8 1.7 0.034 13.9 0.0 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4145) Troponin PF00992.15 ETO35986.1 - 0.052 13.6 10.6 0.062 13.3 7.3 1.1 1 0 0 1 1 1 0 Troponin DUF1824 PF08854.5 ETO35986.1 - 0.1 12.2 2.0 0.13 11.9 0.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1824) CorA PF01544.13 ETO35986.1 - 0.34 9.8 6.9 0.43 9.5 4.8 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Pex19 PF04614.7 ETO35986.1 - 0.42 10.1 10.7 0.34 10.4 3.2 2.0 1 1 1 2 2 2 0 Pex19 protein family Baculo_p24 PF05073.7 ETO35986.1 - 0.75 9.3 10.2 0.53 9.8 5.8 1.7 1 1 1 2 2 2 0 Baculovirus P24 capsid protein FERM_M PF00373.13 ETO35986.1 - 2.3 8.4 6.1 4.6 7.4 4.2 1.6 1 1 0 1 1 1 0 FERM central domain Complex1_51K PF01512.12 ETO35987.1 - 3.8e-43 146.8 0.0 7.3e-42 142.6 0.0 2.2 1 1 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 ETO35987.1 - 3.8e-17 61.1 0.5 3.8e-17 61.1 0.3 2.6 3 0 0 3 3 3 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 ETO35987.1 - 9.9e-07 28.5 0.0 1.9e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 SLBB domain DSPc PF00782.15 ETO35988.1 - 2e-25 88.8 0.4 1.3e-24 86.3 0.3 2.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 ETO35988.1 - 7.3e-05 22.2 2.1 0.00019 20.8 0.0 2.2 2 1 0 2 2 2 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 ETO35988.1 - 0.013 15.8 0.0 0.081 13.2 0.0 2.2 2 0 0 2 2 2 0 Rhodanese-like domain Y_phosphatase3 PF13350.1 ETO35988.1 - 0.099 12.8 0.0 0.68 10.1 0.0 2.1 2 0 0 2 2 2 0 Tyrosine phosphatase family Sld5 PF05916.6 ETO35989.1 - 0.00032 20.9 0.8 0.00069 19.8 0.6 1.5 1 0 0 1 1 1 1 GINS complex protein Clathrin_lg_ch PF01086.12 ETO35990.1 - 0.12 12.2 5.5 0.15 11.9 3.8 1.1 1 0 0 1 1 1 0 Clathrin light chain DUF1313 PF07011.6 ETO35990.1 - 0.13 11.9 0.8 0.24 11.0 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1313) DUF4446 PF14584.1 ETO35990.1 - 2.1 8.1 4.0 0.94 9.2 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF2306 PF10067.4 ETO35992.1 - 5.6 7.1 16.6 0.073 13.1 3.1 2.6 2 2 0 2 2 2 0 Predicted membrane protein (DUF2306) Pyridoxal_deC PF00282.14 ETO35993.1 - 0.013 13.9 0.0 0.022 13.2 0.0 1.6 1 1 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Syntaxin-6_N PF09177.6 ETO35993.1 - 0.11 12.9 0.1 1.1 9.6 0.1 2.0 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DegT_DnrJ_EryC1 PF01041.12 ETO35994.1 - 3.5e-07 29.6 0.0 4.4e-07 29.2 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 ETO35994.1 - 0.0031 16.0 0.0 0.0033 15.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 ETO35994.1 - 0.0071 15.1 0.0 0.0087 14.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Amino_oxidase PF01593.19 ETO35995.1 - 1.3e-09 37.6 0.0 3.5e-09 36.2 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NicO PF03824.11 ETO35995.1 - 1.3 8.2 6.0 2 7.6 4.1 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein WD40 PF00400.27 ETO35997.1 - 2.6e-35 119.0 16.1 1.1e-13 50.4 0.1 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO35997.1 - 5e-08 31.5 4.2 0.00034 18.8 0.6 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Pkinase PF00069.20 ETO35998.1 - 1.2e-21 77.0 0.2 1.9e-21 76.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO35998.1 - 1.2e-19 70.3 0.1 2.2e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO35998.1 - 0.012 14.6 0.0 0.029 13.3 0.0 1.6 1 1 0 1 1 1 0 Kinase-like DUF4131 PF13567.1 ETO35998.1 - 2.3 7.5 7.7 19 4.6 4.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) RRM_6 PF14259.1 ETO35999.1 - 5.5e-14 51.9 0.2 9.6e-06 25.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO35999.1 - 3.4e-10 39.4 0.1 0.00056 19.4 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO35999.1 - 4.4e-10 39.2 0.3 5.2e-08 32.6 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro-kuma_activ PF09286.6 ETO36000.1 - 2.9e-15 56.5 0.0 4.8e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Calsarcin PF05556.6 ETO36000.1 - 0.041 13.1 0.2 0.041 13.1 0.2 1.6 2 0 0 2 2 2 0 Calcineurin-binding protein (Calsarcin) Kelch_1 PF01344.20 ETO36002.1 - 3e-07 29.8 11.3 0.0035 16.8 0.4 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO36002.1 - 1.5e-06 27.8 1.2 0.092 12.5 0.0 3.7 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO36002.1 - 1.5e-05 24.5 7.1 0.029 14.1 0.1 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO36002.1 - 6.6e-05 22.7 10.4 0.044 13.7 0.6 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 ETO36002.1 - 0.00011 22.1 6.0 0.016 15.3 0.1 4.1 4 0 0 4 4 4 2 Kelch motif DUF2272 PF10030.4 ETO36002.1 - 0.00067 19.1 0.1 0.045 13.2 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2272) Kelch_3 PF13415.1 ETO36002.1 - 0.1 12.8 0.4 9.3 6.5 0.2 3.5 3 0 0 3 3 3 0 Galactose oxidase, central domain zf-TRAF PF02176.13 ETO36003.1 - 0.00012 22.3 2.6 0.00012 22.3 1.8 2.2 2 0 0 2 2 2 1 TRAF-type zinc finger Frigida PF07899.6 ETO36003.1 - 0.0082 14.9 3.5 0.011 14.4 2.4 1.2 1 0 0 1 1 1 1 Frigida-like protein TpcC PF12642.2 ETO36004.1 - 0.06 12.8 0.4 0.099 12.1 0.0 1.5 2 0 0 2 2 2 0 Conjugative transposon protein TcpC Beta_helix PF13229.1 ETO36005.1 - 0.18 11.5 32.8 0.052 13.3 3.1 3.4 2 1 1 3 3 3 0 Right handed beta helix region DUF3328 PF11807.3 ETO36006.1 - 0.015 14.9 0.4 0.033 13.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) G_glu_transpept PF01019.16 ETO36007.1 - 3e-82 276.7 2.5 5.2e-57 193.4 0.0 3.9 2 2 0 2 2 2 2 Gamma-glutamyltranspeptidase Fringe PF02434.11 ETO36008.1 - 7.8e-05 22.0 0.3 0.00011 21.4 0.2 1.3 1 0 0 1 1 1 1 Fringe-like WD40 PF00400.27 ETO36009.1 - 2.1e-12 46.3 2.0 7.2e-11 41.5 0.1 2.6 2 1 0 2 2 2 1 WD domain, G-beta repeat HAD PF12710.2 ETO36009.1 - 0.063 13.4 0.0 0.064 13.4 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF870 PF05912.6 ETO36009.1 - 0.072 12.8 0.0 0.12 12.2 0.0 1.4 1 1 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF870) SprB PF13573.1 ETO36009.1 - 0.083 12.5 1.3 0.43 10.2 0.0 2.4 2 0 0 2 2 2 0 SprB repeat RNA_helicase PF00910.17 ETO36010.1 - 0.0027 17.8 0.1 1.2 9.2 0.0 3.0 2 0 0 2 2 2 2 RNA helicase AAA_22 PF13401.1 ETO36010.1 - 0.0063 16.6 1.2 0.39 10.8 0.1 3.2 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETO36010.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain MitMem_reg PF13012.1 ETO36010.1 - 0.43 10.6 0.0 0.43 10.6 0.0 2.9 3 0 0 3 3 3 0 Maintenance of mitochondrial structure and function BHD_1 PF10403.4 ETO36011.1 - 0.35 10.4 2.0 26 4.4 0.1 3.4 3 0 0 3 3 3 0 Rad4 beta-hairpin domain 1 DSPc PF00782.15 ETO36012.1 - 2.4e-05 23.9 4.3 2.4e-05 23.9 3.0 2.2 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain DUF2987 PF11205.3 ETO36012.1 - 0.1 12.2 2.4 0.19 11.4 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2987) DUF1975 PF09318.5 ETO36012.1 - 1.6 8.2 13.8 0.55 9.8 5.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1975) Takusan PF04822.8 ETO36012.1 - 1.7 8.4 4.8 8 6.3 0.7 2.3 2 1 0 2 2 2 0 Takusan Pkinase PF00069.20 ETO36014.1 - 1.8e-46 158.4 0.0 1.2e-34 119.6 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO36014.1 - 3.4e-23 82.0 0.0 1.1e-22 80.4 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETO36014.1 - 0.11 12.1 0.6 0.38 10.4 0.0 2.1 3 0 0 3 3 3 0 Phosphotransferase enzyme family DUF21 PF01595.15 ETO36015.1 - 1.4e-19 70.0 2.0 1.9e-18 66.4 1.4 2.1 1 1 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 ETO36015.1 - 4.5e-08 32.7 0.1 5.8e-05 22.8 0.0 3.3 3 1 0 3 3 3 2 CBS domain FA_hydroxylase PF04116.8 ETO36017.1 - 2.2e-07 31.2 10.9 2.2e-07 31.2 7.5 3.3 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily EF-hand_1 PF00036.27 ETO36018.1 - 0.035 13.4 0.3 0.081 12.2 0.2 1.6 1 0 0 1 1 1 0 EF hand zf-RING_2 PF13639.1 ETO36019.1 - 1.9e-07 30.8 7.3 1.9e-07 30.8 5.1 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO36019.1 - 3.1e-06 27.1 8.9 3.1e-06 27.1 6.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO36019.1 - 3.9e-06 26.4 8.2 3.9e-06 26.4 5.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 ETO36019.1 - 9.3e-05 22.2 9.9 0.00022 21.0 6.8 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 ETO36019.1 - 9.4e-05 22.0 8.1 9.4e-05 22.0 5.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 ETO36019.1 - 0.00027 20.6 3.4 0.00034 20.2 1.3 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 ETO36019.1 - 0.00057 19.9 2.4 0.0017 18.4 1.7 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 ETO36019.1 - 0.00063 19.4 8.5 0.00063 19.4 5.9 2.4 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.1 ETO36019.1 - 0.015 14.8 5.1 0.052 13.1 3.6 2.0 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Mu-like_Com PF10122.4 ETO36019.1 - 0.031 13.3 1.8 0.061 12.3 1.2 1.5 1 0 0 1 1 1 0 Mu-like prophage protein Com DUF4463 PF14703.1 ETO36019.1 - 0.031 14.7 1.9 0.031 14.7 1.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) zf-Apc11 PF12861.2 ETO36019.1 - 0.039 13.7 2.0 0.072 12.9 1.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 ETO36019.1 - 0.053 13.3 5.6 0.03 14.1 2.2 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein CDC45 PF02724.9 ETO36019.1 - 0.057 11.4 4.8 0.07 11.1 3.3 1.1 1 0 0 1 1 1 0 CDC45-like protein ELL PF10390.4 ETO36019.1 - 0.11 11.7 7.7 0.12 11.5 5.3 1.1 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL Peptidase_S49_N PF08496.5 ETO36019.1 - 0.25 11.0 5.8 0.4 10.4 4.0 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal zf-Sec23_Sec24 PF04810.10 ETO36019.1 - 0.3 10.6 4.1 0.91 9.1 2.8 1.8 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger AAA_11 PF13086.1 ETO36019.1 - 0.46 10.0 6.3 0.66 9.4 4.4 1.2 1 0 0 1 1 1 0 AAA domain Neur_chan_memb PF02932.11 ETO36019.1 - 0.82 9.4 7.3 0.039 13.8 1.4 1.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region ScpA_ScpB PF02616.9 ETO36019.1 - 2.5 7.6 11.1 3.4 7.1 7.7 1.3 1 1 0 1 1 1 0 ScpA/B protein YqfQ PF14181.1 ETO36019.1 - 3 7.8 13.0 4.5 7.2 9.0 1.2 1 0 0 1 1 1 0 YqfQ-like protein WD40 PF00400.27 ETO36020.1 - 1.3e-46 154.8 3.7 1.6e-12 46.7 0.0 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 ETO36020.1 - 1.7e-08 34.3 0.1 0.00085 19.0 0.1 2.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 ETO36020.1 - 4.1e-06 25.8 2.5 0.059 12.1 0.0 3.3 1 1 2 3 3 3 3 Nup133 N terminal like PD40 PF07676.7 ETO36020.1 - 3.7e-05 23.2 3.6 2.9 7.6 0.0 4.9 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO36020.1 - 0.00023 19.5 0.0 0.0093 14.3 0.0 2.0 1 1 1 2 2 2 2 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 ETO36020.1 - 0.00095 18.4 3.6 0.33 10.3 0.0 4.0 4 0 0 4 4 4 1 Proteasome subunit A N-terminal signature DPPIV_N PF00930.16 ETO36020.1 - 0.0014 17.2 0.0 0.17 10.4 0.0 2.8 1 1 2 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nup160 PF11715.3 ETO36020.1 - 0.0018 16.4 0.5 4.4 5.3 0.0 3.2 1 1 2 3 3 3 3 Nucleoporin Nup120/160 DUF1258 PF06869.7 ETO36020.1 - 0.03 13.4 1.4 3 6.8 0.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1258) PQQ_2 PF13360.1 ETO36020.1 - 0.068 12.6 0.1 0.31 10.4 0.0 1.7 1 1 0 1 1 1 0 PQQ-like domain YtpI PF14007.1 ETO36021.1 - 0.05 13.5 0.8 0.05 13.5 0.5 1.7 2 0 0 2 2 2 0 YtpI-like protein DUF912 PF06024.7 ETO36021.1 - 0.14 12.2 1.2 0.24 11.4 0.9 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) GTP_EFTU_D2 PF03144.20 ETO36022.1 - 1.4e-05 25.1 0.1 2.1e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu domain 2 WD40 PF00400.27 ETO36023.1 - 4.4e-12 45.3 1.2 3.3e-05 23.5 0.5 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat NACHT PF05729.7 ETO36024.1 - 2.5e-11 43.4 0.1 5.3e-11 42.4 0.1 1.6 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETO36024.1 - 2.3e-07 31.0 0.1 7.9e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 ETO36024.1 - 1.5e-06 27.3 0.5 2.1e-06 26.8 0.3 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.24 ETO36024.1 - 1.9e-06 28.0 0.0 3.6e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AFG1_ATPase PF03969.11 ETO36024.1 - 2e-05 23.5 0.1 2.8e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 AFG1-like ATPase Sigma54_activ_2 PF14532.1 ETO36024.1 - 0.00037 20.5 0.0 0.00065 19.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.1 ETO36024.1 - 0.00041 20.3 0.0 0.0036 17.3 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 ETO36024.1 - 0.00046 20.9 2.1 0.00072 20.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 ETO36024.1 - 0.00064 19.8 0.0 0.0023 18.1 0.0 2.0 1 0 0 1 1 1 1 RNA helicase AAA_32 PF13654.1 ETO36024.1 - 0.00092 17.9 0.5 0.0016 17.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETO36024.1 - 0.0011 19.3 0.0 0.0011 19.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain PhoH PF02562.11 ETO36024.1 - 0.0051 16.0 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_30 PF13604.1 ETO36024.1 - 0.0092 15.5 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 ETO36024.1 - 0.014 15.3 0.0 0.039 13.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 ETO36024.1 - 0.014 14.7 0.2 0.039 13.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 ETO36024.1 - 0.016 14.9 0.1 0.28 10.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) MobB PF03205.9 ETO36024.1 - 0.017 14.8 2.0 0.018 14.7 0.0 2.0 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 ETO36024.1 - 0.018 15.3 0.0 0.035 14.3 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.1 ETO36024.1 - 0.023 14.4 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 ETO36024.1 - 0.027 14.4 0.2 0.1 12.5 0.0 2.0 3 0 0 3 3 3 0 AAA domain ADK PF00406.17 ETO36024.1 - 0.03 14.1 0.3 1.3 8.9 0.0 2.5 3 0 0 3 3 3 0 Adenylate kinase NTPase_1 PF03266.10 ETO36024.1 - 0.04 13.6 0.3 0.19 11.4 0.0 2.1 2 0 0 2 2 2 0 NTPase Sigma54_activat PF00158.21 ETO36024.1 - 0.042 13.3 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain SRP54 PF00448.17 ETO36024.1 - 0.05 13.0 0.0 0.086 12.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain IstB_IS21 PF01695.12 ETO36024.1 - 0.057 12.8 0.1 0.11 11.8 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein ResIII PF04851.10 ETO36024.1 - 0.058 13.2 0.7 0.23 11.2 0.0 2.1 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Miro PF08477.8 ETO36024.1 - 0.059 13.8 2.2 0.26 11.7 0.0 3.0 3 1 0 3 3 3 0 Miro-like protein PduV-EutP PF10662.4 ETO36024.1 - 0.069 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 ETO36024.1 - 0.11 12.4 0.0 0.51 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 ETO36024.1 - 0.13 11.8 0.1 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DDHD PF02862.12 ETO36024.1 - 0.28 10.9 2.5 0.44 10.3 1.7 1.2 1 0 0 1 1 1 0 DDHD domain AAA_24 PF13479.1 ETO36024.1 - 0.3 10.6 5.2 0.11 12.0 1.0 2.3 2 1 0 2 2 2 0 AAA domain Atrophin-1 PF03154.10 ETO36024.1 - 3.5 5.6 5.8 4.9 5.1 4.0 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF1947 PF09183.5 ETO36024.1 - 9 6.1 8.0 18 5.2 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1947) UPF0104 PF03706.8 ETO36025.1 - 0.014 14.6 1.9 0.017 14.4 1.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) ABC_cobalt PF09819.4 ETO36025.1 - 0.3 11.0 3.7 0.42 10.5 2.3 1.4 1 1 0 1 1 1 0 ABC-type cobalt transport system, permease component DUF3328 PF11807.3 ETO36025.1 - 0.79 9.3 3.2 0.81 9.3 0.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3328) zf-DHHC PF01529.15 ETO36025.1 - 1 8.7 5.4 1.2 8.4 3.7 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase VirB3 PF05101.8 ETO36025.1 - 1.1 9.2 3.7 1.3 9.0 0.3 2.0 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein SecY PF00344.15 ETO36025.1 - 1.2 8.0 5.1 1.4 7.7 3.6 1.1 1 0 0 1 1 1 0 SecY translocase WD40 PF00400.27 ETO36027.1 - 2.4e-63 207.8 27.0 2e-11 43.2 0.1 8.0 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO36027.1 - 9.7e-12 43.7 3.6 0.007 14.5 0.2 5.5 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO36027.1 - 0.00026 19.8 9.6 0.99 8.0 1.5 4.6 1 1 2 3 3 3 3 Nup133 N terminal like DUF1900 PF08954.6 ETO36027.1 - 0.061 12.8 0.3 0.97 8.9 0.0 3.0 4 1 1 5 5 5 0 Domain of unknown function (DUF1900) PAS PF00989.19 ETO36029.1 - 0.063 13.0 1.6 0.13 12.0 0.2 2.3 2 1 0 2 2 2 0 PAS fold DUF4200 PF13863.1 ETO36030.1 - 0.016 15.1 1.4 0.016 15.1 1.0 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4200) DUF4201 PF13870.1 ETO36030.1 - 0.12 11.7 29.3 0.016 14.6 8.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) Secretin_N_2 PF07655.8 ETO36030.1 - 0.17 12.2 1.6 0.43 10.9 1.1 1.7 1 0 0 1 1 1 0 Secretin N-terminal domain DUF4140 PF13600.1 ETO36030.1 - 0.27 11.6 15.8 0.6 10.5 1.1 3.4 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Zein-binding PF04576.10 ETO36030.1 - 1.3 9.2 14.3 0.47 10.6 0.7 3.3 3 0 0 3 3 3 0 Zein-binding DUF2730 PF10805.3 ETO36030.1 - 5.9 6.6 12.1 2.1 8.1 0.4 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2730) Prefoldin_2 PF01920.15 ETO36030.1 - 6.6 6.5 33.4 0.46 10.2 3.2 4.2 3 1 1 4 4 4 0 Prefoldin subunit FlxA PF14282.1 ETO36030.1 - 8.9 6.3 33.7 0.066 13.1 3.3 4.4 2 1 0 3 3 3 0 FlxA-like protein CASP_C PF08172.7 ETO36031.1 - 1.9e-19 69.6 24.6 2.1e-18 66.2 17.1 2.0 1 1 0 1 1 1 1 CASP C terminal Striatin PF08232.7 ETO36031.1 - 0.076 13.3 19.7 0.2 11.9 0.9 2.6 1 1 0 2 2 2 0 Striatin family DivIC PF04977.10 ETO36031.1 - 0.11 12.0 16.9 0.071 12.5 4.6 2.8 2 0 0 2 2 2 0 Septum formation initiator FtsL PF04999.8 ETO36031.1 - 0.12 12.1 0.4 0.12 12.1 0.2 1.7 2 0 0 2 2 2 0 Cell division protein FtsL DUF3450 PF11932.3 ETO36031.1 - 0.14 11.3 8.4 0.33 10.1 0.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.4 ETO36031.1 - 0.2 11.4 14.3 0.68 9.7 0.7 3.1 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.3 ETO36031.1 - 0.21 11.3 17.0 0.17 11.6 1.1 3.1 2 2 1 3 3 3 0 TATA element modulatory factor 1 TATA binding CtIP_N PF10482.4 ETO36031.1 - 0.51 10.1 11.8 0.27 11.0 1.5 2.5 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain bZIP_2 PF07716.10 ETO36031.1 - 0.69 9.7 13.6 0.27 11.0 0.9 3.5 2 1 1 3 3 3 0 Basic region leucine zipper Atg14 PF10186.4 ETO36031.1 - 1 8.2 12.8 0.14 11.0 2.3 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Menin PF05053.8 ETO36031.1 - 1.1 7.3 6.0 1.2 7.2 4.1 1.2 1 0 0 1 1 1 0 Menin TAF8_C PF10406.4 ETO36031.1 - 2.6 8.1 4.7 0.9 9.6 0.1 2.4 3 0 0 3 3 3 0 Transcription factor TFIID complex subunit 8 C-term DUF3552 PF12072.3 ETO36031.1 - 6.9 5.8 14.9 4.2 6.5 1.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) CASP_C PF08172.7 ETO36032.1 - 1.9e-07 30.4 0.1 2.3e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 CASP C terminal WD40 PF00400.27 ETO36033.1 - 1.2e-21 75.6 7.7 1.6e-12 46.7 0.4 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO36033.1 - 0.0015 17.3 0.9 0.085 11.5 0.1 2.2 1 1 0 2 2 2 2 Nup133 N terminal like Nup160 PF11715.3 ETO36033.1 - 0.0027 15.9 0.4 1.7 6.7 0.0 2.8 1 1 2 3 3 3 2 Nucleoporin Nup120/160 NAAA-beta PF15508.1 ETO36034.1 - 1.6e-14 54.0 0.0 2.1e-13 50.4 0.0 2.2 2 0 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase CBAH PF02275.13 ETO36034.1 - 0.0014 18.1 0.0 0.68 9.2 0.0 2.4 2 0 0 2 2 2 2 Linear amide C-N hydrolases, choloylglycine hydrolase family Kelch_6 PF13964.1 ETO36035.1 - 8.3e-07 28.9 3.1 0.057 13.6 0.1 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETO36035.1 - 0.00089 18.9 0.2 0.9 9.3 0.0 3.7 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO36035.1 - 0.0022 17.9 1.9 6.9 6.7 0.0 4.1 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO36035.1 - 0.0058 16.1 3.6 2.3 7.8 0.1 4.1 4 0 0 4 4 4 2 Kelch motif HDNR PF15115.1 ETO36035.1 - 0.026 14.4 0.2 0.052 13.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function with conserved HDNR motif BcrAD_BadFG PF01869.15 ETO36036.1 - 0.19 10.9 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family DUF1539 PF07560.6 ETO36037.1 - 0.19 11.5 5.3 0.15 11.9 2.7 1.5 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1539) TerY-C PF15616.1 ETO36037.1 - 1.1 9.1 4.0 0.66 9.9 1.1 1.8 1 1 1 2 2 2 0 TerY-C metal binding domain HSP70 PF00012.15 ETO36039.1 - 0.00097 17.1 0.0 0.023 12.6 0.0 2.5 1 1 0 1 1 1 1 Hsp70 protein VWA_2 PF13519.1 ETO36039.1 - 0.16 12.0 0.0 0.4 10.7 0.0 1.7 1 1 0 1 1 1 0 von Willebrand factor type A domain RVT_1 PF00078.22 ETO36040.1 - 0.00075 18.9 0.2 0.0054 16.1 0.1 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SNARE PF05739.14 ETO36041.1 - 5.7e-19 67.5 6.7 7.4e-19 67.1 4.7 1.1 1 0 0 1 1 1 1 SNARE domain RmuC PF02646.11 ETO36041.1 - 0.0098 14.7 1.0 0.011 14.5 0.7 1.1 1 0 0 1 1 1 1 RmuC family DUF2951 PF11166.3 ETO36041.1 - 0.016 15.0 1.7 0.022 14.5 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) DUF2232 PF09991.4 ETO36041.1 - 0.024 13.6 0.6 0.035 13.1 0.2 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF2194 PF09960.4 ETO36041.1 - 0.025 12.6 0.8 0.026 12.5 0.6 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) V-SNARE PF05008.10 ETO36041.1 - 0.026 14.6 4.4 0.22 11.7 0.4 2.1 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Herpes_US9 PF06072.6 ETO36041.1 - 0.039 13.7 0.2 0.066 13.0 0.2 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Pex24p PF06398.6 ETO36041.1 - 0.068 11.9 0.4 0.074 11.8 0.3 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin BRX PF08381.6 ETO36041.1 - 0.085 11.9 0.6 0.76 8.8 0.0 2.1 2 0 0 2 2 2 0 Transcription factor regulating root and shoot growth via Pin3 DUF1664 PF07889.7 ETO36041.1 - 0.09 12.5 2.5 0.19 11.5 1.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Syntaxin PF00804.20 ETO36041.1 - 0.094 12.8 3.1 0.12 12.5 2.1 1.1 1 0 0 1 1 1 0 Syntaxin DUF912 PF06024.7 ETO36041.1 - 0.29 11.2 2.4 0.31 11.1 0.3 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PA26 PF04636.8 ETO36042.1 - 1.8e-36 125.8 0.2 2.3e-36 125.4 0.1 1.2 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) DUF966 PF06136.8 ETO36043.1 - 5.2 6.3 15.7 6.4 6.0 10.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) ORC6 PF05460.8 ETO36043.1 - 6.2 5.8 19.6 8.1 5.4 13.6 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SHOCT PF09851.4 ETO36045.1 - 0.13 11.7 2.7 0.43 10.1 0.0 3.0 3 0 0 3 3 3 0 Short C-terminal domain RSN1_TM PF13967.1 ETO36045.1 - 7.7 6.0 7.5 0.18 11.3 0.2 1.8 2 0 0 2 2 2 0 Late exocytosis, associated with Golgi transport Helicase_C PF00271.26 ETO36046.1 - 1.6e-19 69.5 0.0 4.3e-19 68.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETO36046.1 - 7.9e-19 67.7 0.0 1e-17 64.1 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase RQC PF09382.5 ETO36046.1 - 2.1e-08 33.7 0.0 4.8e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 RQC domain HRDC PF00570.18 ETO36046.1 - 0.00017 21.2 0.0 0.00067 19.3 0.0 1.9 2 0 0 2 2 2 1 HRDC domain Secretin_N_2 PF07655.8 ETO36047.1 - 0.063 13.6 2.4 0.19 12.1 1.7 1.8 1 0 0 1 1 1 0 Secretin N-terminal domain PB1 PF00564.19 ETO36048.1 - 1.1e-12 47.4 0.1 1.5e-12 47.0 0.1 1.2 1 0 0 1 1 1 1 PB1 domain NGP1NT PF08153.7 ETO36048.1 - 0.067 13.1 0.2 0.099 12.5 0.2 1.3 1 0 0 1 1 1 0 NGP1NT (NUC091) domain WD40 PF00400.27 ETO36049.1 - 3.7e-32 109.0 15.5 3.4e-11 42.5 0.1 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO36049.1 - 4.6e-07 28.3 3.6 0.00011 20.5 0.2 2.8 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Phosphorylase PF00343.15 ETO36049.1 - 0.026 12.4 0.2 0.03 12.2 0.1 1.2 1 0 0 1 1 1 0 Carbohydrate phosphorylase Kelch_6 PF13964.1 ETO36049.1 - 0.036 14.2 2.4 2.8 8.2 0.0 3.3 2 1 1 3 3 3 0 Kelch motif RED_C PF07807.6 ETO36049.1 - 0.049 13.8 0.2 15 5.8 0.0 3.0 1 1 1 3 3 3 0 RED-like protein C-terminal region CUE PF02845.11 ETO36051.1 - 0.3 10.6 4.7 6.3 6.3 0.0 3.2 3 0 0 3 3 3 0 CUE domain Peptidase_S64 PF08192.6 ETO36051.1 - 0.42 8.8 5.5 0.48 8.6 3.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 MIP-T3 PF10243.4 ETO36051.1 - 0.97 7.8 8.4 1.2 7.4 5.8 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PHD PF00628.24 ETO36052.1 - 3.7e-09 36.1 5.2 8e-09 35.0 3.6 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 ETO36052.1 - 0.0033 16.7 2.2 0.0033 16.7 1.5 1.7 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.17 ETO36052.1 - 0.012 15.3 0.5 0.012 15.3 0.3 1.6 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Vfa1 PF08432.5 ETO36052.1 - 0.012 15.6 9.7 0.011 15.7 6.2 1.3 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 ORC6 PF05460.8 ETO36052.1 - 0.059 12.4 4.7 0.078 12.0 3.2 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DZR PF12773.2 ETO36052.1 - 0.07 12.9 4.3 0.45 10.3 3.0 2.2 1 1 0 1 1 1 0 Double zinc ribbon FLO_LFY PF01698.11 ETO36052.1 - 0.16 10.7 5.7 0.22 10.3 4.0 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein C1_3 PF07649.7 ETO36052.1 - 0.43 10.6 4.6 0.92 9.5 3.2 1.6 1 0 0 1 1 1 0 C1-like domain DDRGK PF09756.4 ETO36052.1 - 0.6 9.4 11.4 0.82 9.0 7.9 1.2 1 0 0 1 1 1 0 DDRGK domain NARP1 PF12569.3 ETO36052.1 - 0.66 8.6 7.1 0.81 8.3 4.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF1677 PF07911.8 ETO36052.1 - 0.86 9.8 6.7 5.9 7.1 4.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1677) FYDLN_acid PF09538.5 ETO36052.1 - 0.88 10.1 17.4 0.054 14.0 6.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Nop25 PF09805.4 ETO36052.1 - 1.3 9.0 19.0 0.36 10.8 10.1 1.8 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) XRN_N PF03159.13 ETO36052.1 - 1.6 8.0 5.8 2.3 7.5 4.0 1.2 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus Cwf_Cwc_15 PF04889.7 ETO36052.1 - 2.3 7.8 20.7 0.034 13.8 8.1 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Sec62 PF03839.11 ETO36052.1 - 3.6 6.9 6.5 5 6.4 4.5 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4407 PF14362.1 ETO36052.1 - 4.6 6.0 6.6 6.5 5.6 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Gag_spuma PF03276.9 ETO36052.1 - 6.4 4.9 7.2 8.6 4.5 5.0 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Pox_Ag35 PF03286.9 ETO36052.1 - 7.4 6.0 16.7 0.1 12.0 6.1 1.7 2 0 0 2 2 2 0 Pox virus Ag35 surface protein NPR3 PF03666.8 ETO36052.1 - 7.6 4.9 9.1 9.8 4.5 6.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Prim_Zn_Ribbon PF08273.7 ETO36052.1 - 8.4 6.5 7.6 6.3 6.9 0.0 3.0 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase Herpes_UL92 PF03048.9 ETO36053.1 - 0.0066 16.0 3.4 0.0074 15.8 0.0 2.0 2 0 0 2 2 2 1 UL92 family DUF3149 PF11346.3 ETO36053.1 - 0.013 15.0 0.1 0.028 13.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) WD40 PF00400.27 ETO36055.1 - 2.2e-12 46.3 6.6 3.1e-06 26.8 0.6 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat AUX_IAA PF02309.11 ETO36056.1 - 0.014 15.1 0.2 0.017 14.8 0.2 1.3 1 0 0 1 1 1 0 AUX/IAA family DUF2305 PF10230.4 ETO36057.1 - 3.1e-22 79.2 1.4 5e-22 78.5 1.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) TMEM154 PF15102.1 ETO36057.1 - 0.0019 17.9 0.8 1 9.0 0.0 2.4 2 0 0 2 2 2 2 TMEM154 protein family Lipase_3 PF01764.20 ETO36057.1 - 0.0048 16.5 0.1 0.0071 15.9 0.1 1.3 1 0 0 1 1 1 1 Lipase (class 3) EST1_DNA_bind PF10373.4 ETO36057.1 - 0.011 15.0 2.0 0.016 14.4 1.0 1.4 1 1 0 1 1 1 0 Est1 DNA/RNA binding domain DUF4446 PF14584.1 ETO36057.1 - 0.12 12.1 1.1 9.7 6.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) UspB PF10625.4 ETO36057.1 - 0.57 9.9 3.8 0.16 11.7 0.4 1.7 2 0 0 2 2 2 0 Universal stress protein B (UspB) OSTbeta PF15048.1 ETO36057.1 - 1 9.4 5.5 12 5.9 0.0 2.9 3 0 0 3 3 3 0 Organic solute transporter subunit beta protein FAM176 PF14851.1 ETO36057.1 - 2.1 8.0 4.7 2.5 7.7 0.2 2.4 3 0 0 3 3 3 0 FAM176 family DUF2305 PF10230.4 ETO36058.1 - 1.1e-11 44.6 0.0 1.5e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Arch_ATPase PF01637.13 ETO36059.1 - 5.1e-05 23.0 1.2 5.1e-05 23.0 0.8 2.8 3 1 0 3 3 3 1 Archaeal ATPase AAA_22 PF13401.1 ETO36059.1 - 0.00011 22.3 0.8 0.0022 18.1 0.1 3.0 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETO36059.1 - 0.009 16.0 0.0 0.026 14.5 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 ETO36059.1 - 0.01 16.6 0.7 0.1 13.4 0.5 2.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 ETO36059.1 - 0.019 14.8 1.1 0.13 12.1 0.2 2.8 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 ETO36059.1 - 0.023 13.8 0.0 0.057 12.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_10 PF12846.2 ETO36059.1 - 0.024 14.0 0.1 0.049 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA-like domain AAA PF00004.24 ETO36059.1 - 0.031 14.4 1.1 0.55 10.4 0.8 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 ETO36059.1 - 0.049 13.0 0.0 0.31 10.4 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_5 PF07728.9 ETO36059.1 - 0.061 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Miro PF08477.8 ETO36059.1 - 0.063 13.7 0.0 0.18 12.2 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein AAA_33 PF13671.1 ETO36059.1 - 0.069 13.0 0.0 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 ETO36059.1 - 0.077 13.1 0.6 1.5 9.0 0.0 2.9 3 0 0 3 3 3 0 RNA helicase AAA_24 PF13479.1 ETO36059.1 - 0.079 12.5 0.0 0.24 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain SPOC PF07744.8 ETO36059.1 - 0.092 13.2 0.0 0.34 11.3 0.0 1.9 1 0 0 1 1 1 0 SPOC domain AAA_19 PF13245.1 ETO36059.1 - 0.19 11.4 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain WD40 PF00400.27 ETO36060.1 - 5.6e-50 165.5 22.8 2.5e-12 46.1 0.1 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO36060.1 - 1.4e-08 33.4 5.4 0.014 13.6 0.0 4.8 2 2 2 4 4 4 4 Nucleoporin Nup120/160 Glyphos_transf PF04464.9 ETO36060.1 - 0.0096 14.7 0.1 0.015 14.1 0.1 1.2 1 0 0 1 1 1 1 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase DUF3601 PF12208.3 ETO36060.1 - 0.032 14.1 0.2 1.1 9.2 0.0 3.2 2 2 3 5 5 5 0 Domain of unknown function (DUF3601) USP7_C2 PF14533.1 ETO36060.1 - 0.15 11.4 0.3 38 3.6 0.0 3.4 3 1 0 3 3 3 0 Ubiquitin-specific protease C-terminal WD40 PF00400.27 ETO36061.1 - 1.8e-21 75.1 14.9 1.4e-09 37.4 0.5 4.1 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO36061.1 - 0.0086 14.2 1.2 0.54 8.3 0.4 2.7 1 1 0 2 2 2 2 Nucleoporin Nup120/160 WD40 PF00400.27 ETO36062.1 - 6.6e-12 44.8 0.5 1.1e-09 37.8 0.0 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat WD40 PF00400.27 ETO36063.1 - 2.9e-65 213.9 24.9 4.7e-11 42.1 0.2 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO36063.1 - 3.6e-09 35.3 8.5 0.00054 18.2 0.4 5.4 1 1 4 6 6 6 5 Nucleoporin Nup120/160 WD40 PF00400.27 ETO36064.1 - 3.9e-26 89.9 4.8 3.5e-12 45.6 0.3 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO36064.1 - 0.00036 18.7 0.2 0.11 10.6 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO36064.1 - 0.16 12.1 1.1 16 5.8 0.1 2.5 2 0 0 2 2 2 0 Kelch motif WD40 PF00400.27 ETO36065.1 - 6.3e-34 114.6 4.2 4.8e-12 45.2 0.0 4.0 4 0 0 4 4 4 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO36065.1 - 0.0015 17.3 0.4 0.0064 15.2 0.2 1.9 1 1 0 1 1 1 1 Nup133 N terminal like Coatomer_WDAD PF04053.9 ETO36065.1 - 0.002 17.0 0.0 0.0024 16.7 0.0 1.0 1 0 0 1 1 1 1 Coatomer WD associated region Nup160 PF11715.3 ETO36065.1 - 0.0035 15.5 0.2 1 7.4 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Mid2 PF04478.7 ETO36065.1 - 0.0073 15.7 0.0 3.8 6.9 0.0 2.2 2 0 0 2 2 2 2 Mid2 like cell wall stress sensor PD40 PF07676.7 ETO36065.1 - 0.013 15.1 3.0 3.2 7.5 0.1 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 ETO36065.1 - 0.013 14.5 0.1 4.8 6.1 0.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1258) Proteasome_A_N PF10584.4 ETO36065.1 - 0.15 11.4 1.1 2 7.8 0.0 2.4 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 ETO36066.1 - 1.2e-13 50.4 9.4 4e-10 39.1 0.4 2.8 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO36066.1 - 0.013 13.6 2.3 0.77 7.8 0.1 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 VWA_2 PF13519.1 ETO36068.1 - 1.7e-07 31.5 0.0 3.3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 ETO36068.1 - 0.0028 17.4 0.0 0.9 9.2 0.0 2.7 3 0 0 3 3 3 2 von Willebrand factor type A domain Aa_trans PF01490.13 ETO36068.1 - 0.17 10.3 0.0 0.24 9.8 0.0 1.1 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein 2Fe-2S_thioredx PF01257.14 ETO36069.1 - 1.6e-44 151.0 1.4 2.2e-44 150.5 1.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Suf PF05843.9 ETO36070.1 - 0.14 11.8 3.8 0.22 11.2 2.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Menin PF05053.8 ETO36070.1 - 0.32 9.1 6.5 0.34 9.0 4.5 1.1 1 0 0 1 1 1 0 Menin RIC3 PF15361.1 ETO36070.1 - 3.3 7.9 10.3 0.27 11.4 0.3 2.3 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 SR-25 PF10500.4 ETO36070.1 - 9.1 5.6 26.9 0.23 10.9 12.8 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Gln-synt_C PF00120.19 ETO36073.1 - 1.8e-59 201.0 0.1 8.1e-59 198.8 0.0 1.8 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 ETO36073.1 - 0.025 14.1 0.0 0.079 12.5 0.0 1.8 1 0 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain DUF3270 PF11674.3 ETO36074.1 - 0.059 13.3 1.4 0.34 10.9 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) Serinc PF03348.10 ETO36075.1 - 0.027 13.1 0.0 0.033 12.9 0.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) BatD PF13584.1 ETO36075.1 - 0.1 11.1 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance Secretin_N_2 PF07655.8 ETO36076.1 - 0.032 14.6 5.5 0.061 13.7 3.8 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain DUF912 PF06024.7 ETO36076.1 - 0.17 11.9 3.4 0.11 12.5 0.6 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Arrestin_C PF02752.17 ETO36076.1 - 0.24 11.5 6.6 0.13 12.3 1.9 2.0 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Apis_Csd PF11671.3 ETO36076.1 - 1.6 8.5 11.0 16 5.2 7.3 2.1 2 0 0 2 2 2 0 Complementary sex determiner protein zf-C2H2_4 PF13894.1 ETO36078.1 - 0.18 12.1 2.9 1.6 9.2 0.3 2.9 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 ETO36079.1 - 0.00029 20.9 4.1 0.01 16.1 0.2 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger MAT_Alpha1 PF04769.7 ETO36079.1 - 0.0047 16.2 0.2 0.0076 15.6 0.1 1.4 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 CpXC PF14353.1 ETO36079.1 - 0.0075 16.2 1.3 0.014 15.3 0.1 1.9 1 1 1 2 2 2 1 CpXC protein Frag1 PF10277.4 ETO36079.1 - 0.0086 15.5 1.6 0.0088 15.5 1.1 1.2 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF420 PF04238.7 ETO36079.1 - 0.015 15.2 2.7 0.036 14.0 1.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF420) zf-H2C2_2 PF13465.1 ETO36079.1 - 0.021 15.0 1.3 0.021 15.0 0.9 2.2 2 0 0 2 2 2 0 Zinc-finger double domain DUF368 PF04018.8 ETO36079.1 - 0.045 12.9 0.3 0.061 12.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF368) Intg_mem_TP0381 PF09529.5 ETO36079.1 - 0.069 12.3 4.1 0.12 11.6 2.8 1.4 1 0 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) 7TM-7TMR_HD PF07698.6 ETO36079.1 - 0.07 12.5 2.5 0.12 11.7 1.7 1.3 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase zf-C2H2 PF00096.21 ETO36079.1 - 0.16 12.3 0.1 0.16 12.3 0.1 2.7 3 0 0 3 3 2 0 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 ETO36079.1 - 0.17 12.1 1.2 9.8 6.6 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain EphA2_TM PF14575.1 ETO36079.1 - 0.75 10.2 2.9 35 4.8 0.1 2.8 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF4492 PF14899.1 ETO36079.1 - 1.8 8.1 6.7 0.59 9.6 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4492) Cation_ATPase_C PF00689.16 ETO36079.1 - 3.2 7.2 6.8 4.6 6.7 4.7 1.6 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus zf-C2H2_4 PF13894.1 ETO36080.1 - 0.0043 17.2 6.2 0.43 11.0 0.8 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 ETO36080.1 - 0.015 15.1 0.5 0.13 12.1 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 ETO36080.1 - 0.12 12.8 1.1 0.12 12.8 0.7 3.0 2 1 0 2 2 2 0 Zinc finger, C2H2 type WD40 PF00400.27 ETO36081.1 - 1.7e-32 110.1 12.7 5.1e-12 45.1 0.0 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO36081.1 - 2.1e-06 26.2 2.9 0.022 12.8 0.0 3.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 DUF3246 PF11596.3 ETO36082.1 - 0.71 9.1 5.9 0.12 11.6 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) TFIIE_beta PF02186.10 ETO36083.1 - 4.9e-06 26.4 0.3 1.4e-05 24.9 0.2 1.7 1 0 0 1 1 1 1 TFIIE beta subunit core domain PhoQ_Sensor PF08918.5 ETO36083.1 - 3.7 7.0 6.9 0.3 10.5 1.0 1.8 2 0 0 2 2 2 0 PhoQ Sensor DNA_pol_A_exo1 PF01612.15 ETO36084.1 - 3.1e-17 62.6 0.0 4.4e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease Tissue_fac PF01108.12 ETO36084.1 - 0.058 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Tissue factor RR_TM4-6 PF06459.7 ETO36084.1 - 8.8 6.1 7.6 13 5.5 5.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 uDENN PF03456.13 ETO36085.1 - 0.014 15.3 1.2 0.23 11.4 0.9 2.5 1 1 0 1 1 1 0 uDENN domain INTS5_N PF14837.1 ETO36085.1 - 0.024 14.0 0.0 0.042 13.2 0.0 1.6 1 1 0 1 1 1 0 Integrator complex subunit 5 N-terminus Lactamase_B PF00753.22 ETO36086.1 - 4.7e-08 32.9 0.0 1.2e-07 31.6 0.0 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Alkyl_sulf_dimr PF14863.1 ETO36087.1 - 1.3e-19 70.7 0.2 5e-18 65.6 0.1 2.5 1 1 0 1 1 1 1 Alkyl sulfatase dimerisation TPR_MLP1_2 PF07926.7 ETO36089.1 - 0.0028 17.4 18.9 0.0028 17.4 13.1 3.3 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.16 ETO36089.1 - 0.03 14.2 3.4 0.03 14.2 2.3 4.7 3 3 1 4 4 4 0 bZIP transcription factor HsbA PF12296.3 ETO36089.1 - 0.63 9.8 7.4 2.1 8.2 2.1 3.0 2 1 0 2 2 2 0 Hydrophobic surface binding protein A DUF1664 PF07889.7 ETO36089.1 - 0.67 9.7 16.8 0.44 10.3 5.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Suppressor_APC PF11414.3 ETO36089.1 - 2.3 8.0 19.1 0.15 11.8 0.7 3.2 1 1 1 3 3 3 0 Adenomatous polyposis coli tumour suppressor protein GAS PF13851.1 ETO36089.1 - 8.8 5.4 41.6 0.71 9.0 16.8 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Kinesin PF00225.18 ETO36090.1 - 1.3e-52 178.5 11.9 1.1e-51 175.5 8.2 2.1 1 1 0 1 1 1 1 Kinesin motor domain Thioredoxin PF00085.15 ETO36091.1 - 1.9e-22 78.9 0.5 5.1e-22 77.5 0.3 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 ETO36091.1 - 2.9e-06 27.4 0.2 3.8e-05 23.8 0.2 2.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 ETO36091.1 - 1.1e-05 25.5 0.0 0.00038 20.5 0.0 2.9 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_6 PF13848.1 ETO36091.1 - 0.00048 19.9 0.1 0.0014 18.4 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 ETO36091.1 - 0.00052 19.9 0.1 0.0037 17.2 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 ETO36091.1 - 0.0026 17.4 0.2 0.0074 15.9 0.1 1.8 1 1 0 1 1 1 1 AhpC/TSA family TraF PF13728.1 ETO36091.1 - 0.0033 16.9 0.0 0.0057 16.1 0.0 1.4 1 0 0 1 1 1 1 F plasmid transfer operon protein DUF4335 PF14233.1 ETO36091.1 - 0.0055 16.2 0.4 0.012 15.0 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4335) Redoxin PF08534.5 ETO36091.1 - 0.01 15.3 0.4 0.044 13.3 0.2 2.1 1 1 1 2 2 2 0 Redoxin Choline_kinase PF01633.15 ETO36091.1 - 0.011 15.3 3.2 0.021 14.3 0.4 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF953 PF06110.6 ETO36091.1 - 0.09 12.2 0.1 0.26 10.7 0.1 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) FragX_IP PF05994.6 ETO36092.1 - 1e-143 480.0 3.5 1.5e-143 479.5 2.4 1.2 1 0 0 1 1 1 1 Cytoplasmic Fragile-X interacting family SPT16 PF08644.6 ETO36093.1 - 0.016 15.0 4.4 0.016 15.0 3.1 2.4 1 1 2 3 3 3 0 FACT complex subunit (SPT16/CDC68) UPF0449 PF15136.1 ETO36093.1 - 0.03 14.5 1.9 0.09 12.9 1.3 1.9 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 Phage_CRI PF05144.9 ETO36093.1 - 0.068 12.2 2.9 0.11 11.5 2.0 1.3 1 0 0 1 1 1 0 Phage replication protein CRI zf-C3HC4 PF00097.20 ETO36093.1 - 0.078 12.6 15.8 0.22 11.1 10.9 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO36093.1 - 0.12 12.1 13.5 0.28 10.9 9.4 1.6 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 ETO36093.1 - 0.28 11.0 12.7 0.49 10.2 8.8 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 ETO36093.1 - 0.38 10.8 14.2 0.72 9.9 9.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 ETO36093.1 - 3.6 7.2 9.9 8.3 6.0 6.8 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1394 PF07159.7 ETO36095.1 - 0.0032 16.6 0.2 0.0047 16.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) zf-DBF PF07535.7 ETO36096.1 - 0.074 12.7 0.2 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 DBF zinc finger Pkinase PF00069.20 ETO36098.1 - 6.3e-57 192.6 0.2 5.1e-55 186.4 0.2 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO36098.1 - 7.4e-28 97.3 0.0 4.1e-27 94.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.27 ETO36099.1 - 1.7e-52 173.5 21.8 7.5e-11 41.4 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO36099.1 - 4.3e-13 48.2 3.9 0.0019 16.4 0.1 4.5 1 1 2 4 4 4 4 Nucleoporin Nup120/160 zf-TRAF PF02176.13 ETO36100.1 - 0.0024 18.2 1.6 0.0024 18.2 1.1 2.4 2 0 0 2 2 2 1 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 ETO36100.1 - 0.013 15.5 1.3 0.077 13.0 0.3 2.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FERM_C PF09380.5 ETO36100.1 - 0.015 15.4 1.3 0.059 13.5 0.1 2.6 2 0 0 2 2 2 0 FERM C-terminal PH-like domain zf-DHHC PF01529.15 ETO36101.1 - 6.5e-35 120.0 23.9 6.5e-35 120.0 16.5 1.8 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF975 PF06161.6 ETO36101.1 - 0.028 14.1 2.4 0.045 13.5 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF975) TctB PF07331.6 ETO36101.1 - 1.1 8.9 6.2 0.44 10.1 1.9 2.0 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family PUB PF09409.5 ETO36102.1 - 0.038 13.7 1.1 0.063 13.0 0.3 1.7 2 0 0 2 2 2 0 PUB domain PRESAN PF09687.5 ETO36102.1 - 0.45 10.5 10.5 2.4 8.2 7.3 2.0 1 1 0 1 1 1 0 Plasmodium RESA N-terminal WD40 PF00400.27 ETO36104.1 - 3e-15 55.4 5.8 7.8e-11 41.4 0.9 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO36104.1 - 0.0014 16.8 0.4 0.0018 16.5 0.3 1.4 1 1 0 1 1 1 1 Nucleoporin Nup120/160 dDENN PF03455.14 ETO36104.1 - 4 7.5 8.4 1 9.4 1.9 2.7 2 1 1 3 3 3 0 dDENN domain DUF2968 PF11180.3 ETO36104.1 - 4.6 6.5 13.9 0.46 9.8 6.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) WD40 PF00400.27 ETO36105.1 - 8.7e-30 101.5 10.5 4.8e-10 38.9 0.1 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO36105.1 - 2.2e-09 36.0 2.6 3.7e-05 22.0 0.2 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 DUF2559 PF10832.3 ETO36105.1 - 0.25 11.1 1.6 6.3 6.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2559) Spore_coat_CotO PF14153.1 ETO36106.1 - 0.015 14.7 6.4 0.019 14.3 4.4 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Myc_N PF01056.13 ETO36106.1 - 0.02 14.0 4.3 0.022 13.9 3.0 1.1 1 0 0 1 1 1 0 Myc amino-terminal region RasGAP PF00616.14 ETO36106.1 - 0.034 13.8 6.6 0.04 13.5 4.6 1.0 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase MRVI1 PF05781.7 ETO36106.1 - 0.049 12.0 4.0 0.043 12.2 2.8 1.1 1 0 0 1 1 1 0 MRVI1 protein D123 PF07065.9 ETO36106.1 - 0.069 12.2 3.3 0.075 12.0 2.3 1.0 1 0 0 1 1 1 0 D123 RXT2_N PF08595.6 ETO36106.1 - 0.078 12.7 5.4 0.1 12.4 3.7 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Sporozoite_P67 PF05642.6 ETO36106.1 - 0.099 10.4 5.4 0.11 10.3 3.8 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4592 PF15262.1 ETO36106.1 - 0.25 11.9 3.9 0.3 11.6 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4592) TRAP_alpha PF03896.11 ETO36106.1 - 0.36 9.7 3.2 0.42 9.5 2.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.9 ETO36106.1 - 0.38 8.7 5.1 0.38 8.7 3.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Med19 PF10278.4 ETO36106.1 - 0.39 10.3 8.8 0.43 10.2 6.1 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF1510 PF07423.6 ETO36106.1 - 0.54 9.5 10.0 0.72 9.1 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2722 PF10846.3 ETO36106.1 - 0.62 9.0 7.2 0.76 8.7 5.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) BTV_NS2 PF04514.7 ETO36106.1 - 0.87 8.4 7.8 1.1 8.0 5.4 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Vfa1 PF08432.5 ETO36106.1 - 1 9.3 10.5 1.3 8.9 7.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Peptidase_S49_N PF08496.5 ETO36106.1 - 1.2 8.9 6.5 1.4 8.6 4.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3899 PF13038.1 ETO36106.1 - 2.3 8.4 5.3 1.8 8.7 1.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Eapp_C PF10238.4 ETO36106.1 - 2.9 7.7 8.1 3.7 7.4 5.6 1.3 1 1 0 1 1 1 0 E2F-associated phosphoprotein NOA36 PF06524.7 ETO36107.1 - 0.056 12.7 2.5 0.087 12.0 1.7 1.2 1 0 0 1 1 1 0 NOA36 protein G-alpha PF00503.15 ETO36108.1 - 1.4e-12 47.0 1.0 1.9e-12 46.6 0.7 1.2 1 0 0 1 1 1 1 G-protein alpha subunit AA_permease_2 PF13520.1 ETO36109.1 - 1.7e-49 168.5 38.8 1.7e-49 168.5 26.9 1.7 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.16 ETO36109.1 - 3.9e-34 117.8 42.5 6.7e-34 117.0 29.4 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.1 ETO36109.1 - 5.8e-16 58.0 3.0 5.8e-16 58.0 2.1 4.8 5 0 0 5 5 5 1 C-terminus of AA_permease UPF0233 PF06781.7 ETO36109.1 - 2.6 7.7 7.4 1.6 8.4 2.2 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) GFO_IDH_MocA PF01408.17 ETO36110.1 - 3.5e-15 56.5 0.0 6e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 ETO36110.1 - 0.01 15.6 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain DUF1336 PF07059.7 ETO36113.1 - 6.2e-24 84.6 0.0 7.5e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) Mob1_phocein PF03637.12 ETO36114.1 - 4.7e-39 133.8 0.0 5.4e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family TPR_12 PF13424.1 ETO36116.1 - 4.4e-155 503.9 47.5 2e-23 82.1 0.2 9.1 4 2 5 10 10 10 10 Tetratricopeptide repeat TPR_1 PF00515.23 ETO36116.1 - 4.2e-99 320.4 84.2 4.4e-09 35.5 1.0 15.2 15 0 0 15 15 15 14 Tetratricopeptide repeat TPR_11 PF13414.1 ETO36116.1 - 1.6e-88 290.3 46.9 1.4e-16 59.9 0.4 9.8 6 2 3 10 10 10 9 TPR repeat TPR_10 PF13374.1 ETO36116.1 - 1.3e-86 282.3 0.0 7.7e-08 32.0 0.0 15.0 15 0 0 15 15 15 13 Tetratricopeptide repeat TPR_7 PF13176.1 ETO36116.1 - 2.2e-81 261.3 22.0 1.4e-07 30.7 0.0 14.7 15 0 0 15 15 15 13 Tetratricopeptide repeat TPR_2 PF07719.12 ETO36116.1 - 1.6e-76 246.1 62.9 1.6e-07 30.6 0.2 15.3 15 0 0 15 15 15 13 Tetratricopeptide repeat TPR_8 PF13181.1 ETO36116.1 - 2.3e-58 189.6 92.8 4.9e-06 25.9 0.2 15.3 15 0 0 15 15 15 14 Tetratricopeptide repeat TPR_17 PF13431.1 ETO36116.1 - 1.9e-31 105.5 32.9 0.00043 20.2 0.0 15.1 13 1 1 14 14 14 8 Tetratricopeptide repeat TPR_6 PF13174.1 ETO36116.1 - 8.6e-26 88.5 27.0 0.042 14.3 0.1 12.8 13 0 0 13 13 13 7 Tetratricopeptide repeat TPR_16 PF13432.1 ETO36116.1 - 1.2e-25 89.5 0.0 0.0035 17.9 0.0 9.1 7 1 3 10 10 10 6 Tetratricopeptide repeat TPR_14 PF13428.1 ETO36116.1 - 8.3e-15 53.9 0.0 14 6.6 0.0 11.4 13 0 0 13 13 12 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO36116.1 - 1e-14 53.4 6.5 0.11 11.7 0.0 10.3 12 0 0 12 12 12 5 SHNi-TPR Apc3 PF12895.2 ETO36116.1 - 1.3e-12 47.6 54.0 1.9e-05 24.6 0.9 8.6 1 1 8 9 9 9 7 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 ETO36116.1 - 1.5e-10 40.7 39.5 0.51 10.2 0.1 11.6 11 1 0 11 11 11 4 MIT (microtubule interacting and transport) domain TPR_19 PF14559.1 ETO36116.1 - 4.3e-08 33.3 1.9 0.093 13.0 0.0 6.4 4 1 3 7 7 7 1 Tetratricopeptide repeat TPR_3 PF07720.7 ETO36116.1 - 7e-06 25.7 56.4 0.014 15.1 1.3 9.5 10 0 0 10 10 8 4 Tetratricopeptide repeat DUF4213 PF13938.1 ETO36116.1 - 7.8e-06 25.9 0.0 6 7.0 0.0 5.9 4 2 2 6 6 6 1 Domain of unknown function (DUF4213) TPR_5 PF12688.2 ETO36116.1 - 0.0047 16.9 0.3 2.5 8.1 0.0 4.6 3 1 2 5 5 5 1 Tetratrico peptide repeat RPN7 PF10602.4 ETO36116.1 - 2.4 7.4 36.1 1.2 8.4 0.0 8.9 4 3 6 10 10 10 0 26S proteasome subunit RPN7 DUF402 PF04167.8 ETO36116.1 - 5.6 6.8 10.7 21 5.0 0.1 5.1 4 1 1 5 5 5 0 Protein of unknown function (DUF402) Ank_2 PF12796.2 ETO36117.1 - 1.1e-12 48.1 0.3 2.4e-11 43.8 0.2 2.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO36117.1 - 5.9e-11 41.6 0.3 0.00011 21.8 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 ETO36117.1 - 1.8e-08 34.6 0.5 4.1e-05 23.9 0.0 3.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO36117.1 - 1.1e-07 31.4 0.3 0.0007 19.6 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 ETO36117.1 - 1.2e-06 28.5 0.7 0.024 14.8 0.0 2.9 2 2 0 2 2 2 2 Ankyrin repeats (many copies) ArfGap PF01412.13 ETO36118.1 - 1.1e-13 50.9 2.9 1.4e-10 40.9 0.2 2.5 1 1 1 2 2 2 2 Putative GTPase activating protein for Arf DUF4140 PF13600.1 ETO36119.1 - 0.12 12.8 8.1 0.75 10.2 0.0 3.2 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) DUF730 PF05325.6 ETO36119.1 - 0.29 10.9 3.8 0.5 10.1 1.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF730) APG6 PF04111.7 ETO36119.1 - 1.6 7.6 41.5 0.25 10.3 6.3 3.1 1 1 1 3 3 3 0 Autophagy protein Apg6 ERM PF00769.14 ETO36119.1 - 2.5 7.5 24.1 10 5.5 16.5 2.2 1 1 0 1 1 1 0 Ezrin/radixin/moesin family LCM PF04072.9 ETO36120.1 - 2.2e-34 118.6 0.0 4.7e-34 117.5 0.0 1.5 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase DUF1805 PF08827.6 ETO36120.1 - 0.024 14.4 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) WD40 PF00400.27 ETO36122.1 - 6.3e-09 35.3 1.4 1.3e-08 34.4 1.0 1.5 1 0 0 1 1 1 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO36122.1 - 0.00085 17.5 0.2 0.0012 17.0 0.1 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 IncA PF04156.9 ETO36122.1 - 2 7.9 8.5 2.8 7.4 5.9 1.2 1 0 0 1 1 1 0 IncA protein WD40 PF00400.27 ETO36123.1 - 2.6e-44 147.5 10.2 9e-12 44.3 0.1 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO36123.1 - 7e-08 31.0 0.4 0.013 13.6 0.0 3.7 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO36123.1 - 0.0021 16.9 4.5 0.46 9.1 0.8 3.0 1 1 2 3 3 3 2 Nup133 N terminal like Kelch_1 PF01344.20 ETO36124.1 - 3.5e-09 36.0 2.4 7.8e-08 31.7 0.4 3.5 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 ETO36124.1 - 2.6e-05 24.1 0.3 0.046 13.9 0.1 4.0 3 1 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETO36124.1 - 6.3e-05 22.6 0.2 0.0031 17.2 0.0 3.5 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO36124.1 - 0.00046 19.8 6.4 0.019 14.6 0.1 4.7 4 1 1 5 5 5 1 Kelch motif Kelch_5 PF13854.1 ETO36124.1 - 0.0019 18.0 1.4 0.36 10.8 0.1 4.2 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.1 ETO36124.1 - 0.11 12.7 0.1 1.2 9.3 0.0 2.9 5 0 0 5 5 5 0 Galactose oxidase, central domain WD40 PF00400.27 ETO36125.1 - 2.3e-06 27.2 2.3 6.4e-06 25.8 1.6 1.8 1 0 0 1 1 1 1 WD domain, G-beta repeat Kelch_6 PF13964.1 ETO36125.1 - 3.1e-06 27.1 6.1 0.061 13.5 0.0 4.9 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO36125.1 - 4.1e-06 26.2 4.3 0.0076 15.7 0.2 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO36125.1 - 0.0036 16.9 1.3 0.16 11.8 0.1 3.7 4 0 0 4 4 4 1 Kelch motif Glyco_hydro_63 PF03200.11 ETO36126.1 - 2.3e-79 267.2 11.8 5.4e-79 265.9 8.2 1.5 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 ETO36126.1 - 3.5e-06 25.9 1.1 4.9e-06 25.4 0.7 1.1 1 0 0 1 1 1 1 Trehalase Bac_rhamnosid PF05592.6 ETO36126.1 - 0.0035 15.6 0.0 0.0057 14.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase DUF1777 PF08648.7 ETO36127.1 - 0.0068 16.1 30.6 0.0068 16.1 21.2 3.3 2 1 1 3 3 3 1 Protein of unknown function (DUF1777) MMR_HSR1 PF01926.18 ETO36130.1 - 1e-17 64.1 0.0 2.5e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP1_OBG PF01018.17 ETO36130.1 - 4.8e-16 58.8 0.9 8.2e-09 35.2 0.0 2.5 1 1 1 2 2 2 2 GTP1/OBG FeoB_N PF02421.13 ETO36130.1 - 1.8e-06 27.3 0.0 4.6e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.16 ETO36130.1 - 0.001 18.3 0.0 0.0028 16.9 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO36130.1 - 0.0019 17.6 0.0 0.31 10.4 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 ETO36130.1 - 0.0053 15.9 0.0 0.0089 15.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 ETO36130.1 - 0.072 13.5 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein DUF1397 PF07165.6 ETO36130.1 - 0.073 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1397) ABC_tran PF00005.22 ETO36130.1 - 0.13 12.5 1.2 0.83 9.9 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Anoctamin PF04547.7 ETO36130.1 - 0.19 10.3 0.2 0.28 9.8 0.1 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Methyltransf_31 PF13847.1 ETO36131.1 - 3.4e-19 68.9 0.0 4.4e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETO36131.1 - 1.2e-18 67.3 0.0 1.8e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO36131.1 - 2.9e-11 43.9 0.0 4.6e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETO36131.1 - 6e-11 41.8 0.0 7.6e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 ETO36131.1 - 3.6e-10 40.1 0.0 5.3e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO36131.1 - 5.3e-10 39.6 0.0 8e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETO36131.1 - 3.2e-09 36.6 0.0 4.1e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETO36131.1 - 7.3e-07 29.2 0.0 1.4e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETO36131.1 - 4e-05 23.0 0.0 6.1e-05 22.4 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.10 ETO36131.1 - 6e-05 22.7 0.1 0.00081 19.0 0.0 2.0 1 1 1 2 2 2 1 Hypothetical methyltransferase Methyltransf_32 PF13679.1 ETO36131.1 - 7.2e-05 22.5 0.0 9.3e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 ETO36131.1 - 0.00066 19.1 0.0 0.00088 18.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 ETO36131.1 - 0.0015 17.6 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 ETO36131.1 - 0.0031 16.5 0.1 0.0063 15.5 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase UPF0020 PF01170.13 ETO36131.1 - 0.0061 16.1 0.0 0.0079 15.7 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PCMT PF01135.14 ETO36131.1 - 0.01 15.3 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 ETO36131.1 - 0.028 13.5 0.0 0.037 13.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) ArsR PF09824.4 ETO36132.1 - 0.022 14.0 1.3 0.052 12.8 0.7 1.8 1 1 0 2 2 2 0 ArsR transcriptional regulator zf-RING_2 PF13639.1 ETO36132.1 - 0.03 14.1 3.8 0.098 12.5 2.6 1.9 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 ETO36132.1 - 0.084 12.9 4.1 0.63 10.1 2.9 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IncA PF04156.9 ETO36132.1 - 0.17 11.4 8.0 1.2 8.7 4.6 2.2 1 1 1 2 2 2 0 IncA protein DUF641 PF04859.7 ETO36132.1 - 5.1 6.8 9.4 0.89 9.3 1.9 2.7 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) WD40 PF00400.27 ETO36133.1 - 2e-18 65.5 7.3 2.3e-10 39.9 0.9 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO36133.1 - 9.2e-05 20.7 0.3 0.0001 20.6 0.2 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Herpes_UL42 PF02282.11 ETO36133.1 - 0.071 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase processivity factor (UL42) WD40 PF00400.27 ETO36134.1 - 3.6e-56 185.1 22.0 8.2e-10 38.1 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO36134.1 - 7.6e-11 40.8 1.0 0.00098 17.3 0.0 4.1 1 1 2 4 4 4 2 Nucleoporin Nup120/160 DUF1900 PF08954.6 ETO36134.1 - 4.3e-05 23.0 0.4 0.27 10.7 0.0 4.5 5 0 0 5 5 5 1 Domain of unknown function (DUF1900) Methyltransf_25 PF13649.1 ETO36134.1 - 0.0085 16.4 0.0 34 4.8 0.0 3.7 3 0 0 3 3 3 1 Methyltransferase domain Dynamin_M PF01031.15 ETO36135.1 - 2.7e-92 308.7 10.1 2e-53 181.1 0.1 4.2 3 1 1 4 4 4 3 Dynamin central region Dynamin_N PF00350.18 ETO36135.1 - 2.2e-44 151.2 0.3 9e-44 149.2 0.2 2.1 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 ETO36135.1 - 5.3e-25 87.1 6.2 1.4e-24 85.7 4.3 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain DUF4367 PF14285.1 ETO36136.1 - 0.0037 16.6 0.2 0.016 14.5 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4367) T_cell_tran_alt PF15128.1 ETO36136.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 T-cell leukemia translocation-altered WD40 PF00400.27 ETO36137.1 - 5.3e-10 38.7 0.2 1.3e-06 28.0 0.0 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat WD40 PF00400.27 ETO36138.1 - 5e-14 51.5 5.4 5e-10 38.8 0.9 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat TPR_12 PF13424.1 ETO36139.1 - 6.9e-125 407.2 33.2 7.3e-23 80.3 0.1 8.2 4 3 5 9 9 9 9 Tetratricopeptide repeat TPR_10 PF13374.1 ETO36139.1 - 5.3e-58 191.4 0.0 1.7e-05 24.5 0.0 12.8 13 0 0 13 13 13 10 Tetratricopeptide repeat TPR_11 PF13414.1 ETO36139.1 - 1.2e-57 191.4 55.8 1.9e-11 43.4 0.3 8.7 3 3 7 10 10 10 10 TPR repeat TPR_1 PF00515.23 ETO36139.1 - 3e-51 169.0 51.0 6.9e-08 31.7 0.0 13.2 13 0 0 13 13 13 11 Tetratricopeptide repeat TPR_7 PF13176.1 ETO36139.1 - 1.4e-48 158.8 16.5 4.6e-06 26.0 0.0 12.7 13 0 0 13 13 13 8 Tetratricopeptide repeat TPR_2 PF07719.12 ETO36139.1 - 5.1e-46 150.9 39.6 0.00042 20.0 0.0 13.4 13 0 0 13 13 13 11 Tetratricopeptide repeat TPR_8 PF13181.1 ETO36139.1 - 1.7e-26 89.9 60.7 9.4e-06 25.0 0.1 13.2 14 0 0 14 14 13 9 Tetratricopeptide repeat TPR_16 PF13432.1 ETO36139.1 - 2.3e-20 72.7 2.7 0.0019 18.8 0.2 7.8 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETO36139.1 - 1.6e-17 62.1 9.0 0.1 12.8 0.1 11.8 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO36139.1 - 1.4e-12 47.0 0.0 7.5 7.4 0.0 10.7 12 0 0 12 12 11 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETO36139.1 - 3e-12 46.6 2.1 0.12 12.7 0.1 7.5 4 2 5 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.1 ETO36139.1 - 1.6e-09 37.6 11.6 0.36 11.3 0.2 9.8 11 0 0 11 11 10 2 Tetratricopeptide repeat PPR PF01535.15 ETO36139.1 - 0.00012 21.8 8.9 2.9 8.0 0.0 6.5 7 0 0 7 7 7 2 PPR repeat TPR_21 PF09976.4 ETO36139.1 - 0.0069 16.3 1.5 0.19 11.6 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF627 PF04781.7 ETO36139.1 - 0.28 10.8 15.0 2.5 7.7 0.1 7.2 6 2 0 7 7 7 0 Protein of unknown function (DUF627) MIT PF04212.13 ETO36139.1 - 0.42 10.5 29.3 7.4 6.5 0.1 10.0 11 2 1 12 12 12 0 MIT (microtubule interacting and transport) domain MAS20 PF02064.10 ETO36139.1 - 0.45 10.4 4.7 47 3.9 0.0 4.4 6 0 0 6 6 4 0 MAS20 protein import receptor TPR_3 PF07720.7 ETO36139.1 - 4.2 7.2 0.0 4.2 7.2 0.0 7.4 9 0 0 9 9 8 0 Tetratricopeptide repeat WD40 PF00400.27 ETO36140.1 - 1.3e-62 205.5 22.9 1.3e-10 40.7 0.1 6.9 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO36140.1 - 4.3e-11 41.6 0.8 0.011 13.8 0.1 4.8 1 1 4 5 5 5 5 Nucleoporin Nup120/160 Bud13 PF09736.4 ETO36142.1 - 1.5 9.0 5.9 0.63 10.2 0.6 2.1 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex PDZ PF00595.19 ETO36144.1 - 5.8e-05 23.1 0.0 0.00014 21.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 ETO36144.1 - 0.081 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 PDZ domain DENN PF02141.16 ETO36146.1 - 2.9e-42 144.5 4.2 5.6e-42 143.5 2.9 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 ETO36146.1 - 1.4e-09 37.7 2.6 2.1e-09 37.2 0.6 2.3 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.14 ETO36146.1 - 9.3e-06 25.6 2.5 0.00013 21.9 1.2 3.0 2 1 0 2 2 2 1 dDENN domain Kelch_6 PF13964.1 ETO36147.1 - 0.12 12.5 0.1 0.25 11.5 0.0 1.6 2 0 0 2 2 2 0 Kelch motif ZZ PF00569.12 ETO36149.1 - 8.4e-12 44.4 28.6 1.4e-11 43.6 8.0 2.8 2 1 0 2 2 2 2 Zinc finger, ZZ type RNA_polI_A34 PF08208.6 ETO36149.1 - 8.2 6.0 36.0 0.032 13.8 7.5 3.2 3 0 0 3 3 3 0 DNA-directed RNA polymerase I subunit RPA34.5 Tubulin PF00091.20 ETO36151.1 - 4.4e-28 98.5 0.1 1.3e-26 93.7 0.1 2.0 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain XhlA PF10779.4 ETO36151.1 - 0.099 12.5 0.0 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 Haemolysin XhlA Tubulin_C PF03953.12 ETO36152.1 - 0.00036 20.5 0.9 0.0044 17.0 0.7 2.1 1 1 0 1 1 1 1 Tubulin C-terminal domain tRNA-synt_1c_C PF03950.13 ETO36152.1 - 0.06 13.0 0.2 0.13 11.8 0.1 1.6 1 1 1 2 2 2 0 tRNA synthetases class I (E and Q), anti-codon binding domain DUF808 PF05661.7 ETO36153.1 - 0.011 14.5 0.1 0.013 14.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF808) AnfG_VnfG PF03139.10 ETO36153.1 - 0.11 12.3 4.4 0.58 9.9 0.1 2.1 1 1 1 2 2 2 0 Vanadium/alternative nitrogenase delta subunit Kelch_1 PF01344.20 ETO36154.1 - 0.00034 20.1 1.7 0.012 15.1 0.4 2.7 2 1 1 3 3 3 1 Kelch motif Kelch_6 PF13964.1 ETO36154.1 - 0.0012 18.9 1.8 0.14 12.3 0.5 2.7 1 1 1 2 2 2 2 Kelch motif Kelch_4 PF13418.1 ETO36154.1 - 0.0025 17.5 1.3 0.71 9.6 0.2 2.5 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO36154.1 - 0.0036 17.0 2.5 0.043 13.5 0.8 2.6 2 1 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO36154.1 - 0.09 12.9 0.1 0.67 10.1 0.0 2.4 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO36155.1 - 2.3e-06 27.5 3.9 0.48 10.6 0.0 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETO36155.1 - 7.9e-05 22.3 0.2 0.35 10.6 0.0 3.9 4 1 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO36155.1 - 0.0012 18.3 7.5 0.059 12.9 0.0 3.6 3 1 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 ETO36155.1 - 0.0047 16.6 3.7 2.4 8.0 0.0 4.4 3 1 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 ETO36155.1 - 0.01 15.8 3.6 2.5 8.1 0.0 4.2 5 0 0 5 5 5 0 Kelch motif ICMT PF04140.9 ETO36156.1 - 1.1e-28 99.2 1.7 3.4e-28 97.6 1.1 1.8 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 ETO36156.1 - 2.3e-11 43.7 3.0 2.3e-11 43.7 2.1 2.3 2 2 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 ETO36156.1 - 0.093 12.0 3.4 0.41 9.8 2.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) EmrE PF13536.1 ETO36156.1 - 0.78 9.9 11.5 0.14 12.3 2.9 2.8 2 1 0 3 3 3 0 Multidrug resistance efflux transporter DUF2207 PF09972.4 ETO36156.1 - 7.5 5.0 8.3 1.8 7.0 1.0 2.3 1 1 2 3 3 3 0 Predicted membrane protein (DUF2207) CUE PF02845.11 ETO36158.1 - 0.013 15.0 0.1 0.028 13.8 0.0 1.7 1 0 0 1 1 1 0 CUE domain KH_1 PF00013.24 ETO36159.1 - 0.00048 19.7 0.1 0.00092 18.8 0.1 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 ETO36159.1 - 0.0009 18.8 0.1 0.002 17.7 0.1 1.6 1 0 0 1 1 1 1 KH domain TPR_12 PF13424.1 ETO36160.1 - 3.8e-85 279.8 14.9 7.4e-21 73.8 0.3 5.4 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.23 ETO36160.1 - 9.7e-56 183.2 46.1 2.5e-08 33.1 0.6 9.5 10 0 0 10 10 9 8 Tetratricopeptide repeat TPR_11 PF13414.1 ETO36160.1 - 9.6e-54 178.9 21.6 2.6e-14 52.6 1.0 6.3 5 1 1 6 6 6 6 TPR repeat TPR_10 PF13374.1 ETO36160.1 - 6.9e-49 162.4 0.0 8.6e-06 25.5 0.0 9.0 9 0 0 9 9 8 8 Tetratricopeptide repeat TPR_7 PF13176.1 ETO36160.1 - 9.8e-47 153.0 16.8 2.7e-07 29.8 0.1 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 ETO36160.1 - 1.4e-46 152.6 36.2 9.9e-06 25.1 0.1 9.7 10 0 0 10 10 9 9 Tetratricopeptide repeat TPR_8 PF13181.1 ETO36160.1 - 3.7e-41 135.8 48.1 1.2e-06 27.8 1.0 9.8 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_17 PF13431.1 ETO36160.1 - 2.3e-20 71.0 7.7 0.38 11.0 0.0 9.8 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO36160.1 - 2.4e-19 68.0 0.1 0.38 11.4 0.0 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO36160.1 - 4e-17 62.3 0.1 0.097 13.3 0.0 6.1 3 1 4 7 7 7 6 Tetratricopeptide repeat TPR_6 PF13174.1 ETO36160.1 - 2.3e-16 59.0 18.2 0.15 12.6 0.1 8.8 8 0 0 8 8 8 6 Tetratricopeptide repeat Apc3 PF12895.2 ETO36160.1 - 6.6e-12 45.4 26.7 4.1e-05 23.6 4.4 5.1 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 ETO36160.1 - 2.1e-11 42.8 11.1 0.0097 15.1 0.0 7.2 8 0 0 8 8 8 3 SHNi-TPR TPR_19 PF14559.1 ETO36160.1 - 4.5e-11 42.9 2.9 0.0017 18.6 0.0 4.9 3 2 1 4 4 4 3 Tetratricopeptide repeat MIT PF04212.13 ETO36160.1 - 3e-07 30.2 25.8 0.98 9.3 0.0 7.9 7 1 1 8 8 7 4 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 ETO36160.1 - 0.00011 21.8 34.4 0.021 14.6 0.1 8.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETO36160.1 - 0.0002 21.1 0.0 36 4.3 0.0 5.5 3 1 4 7 7 7 0 Tetratricopeptide repeat PPR PF01535.15 ETO36160.1 - 0.00021 21.0 6.3 15 5.8 0.0 6.6 7 0 0 7 7 7 0 PPR repeat DUF3856 PF12968.2 ETO36160.1 - 0.0018 18.0 5.6 0.33 10.7 0.1 3.9 2 1 0 3 3 3 1 Domain of Unknown Function (DUF3856) SLT PF01464.15 ETO36160.1 - 0.035 13.6 0.2 0.27 10.7 0.0 2.6 2 1 2 4 4 4 0 Transglycosylase SLT domain PPR_2 PF13041.1 ETO36160.1 - 0.49 10.4 4.2 1.9 8.5 0.0 4.0 5 0 0 5 5 3 0 PPR repeat family Sel1 PF08238.7 ETO36160.1 - 1.3 9.7 13.9 31 5.3 0.1 6.0 6 0 0 6 6 5 0 Sel1 repeat RRN3 PF05327.6 ETO36161.1 - 1.2e-30 106.2 17.7 6.7e-25 87.2 4.0 2.9 3 0 0 3 3 3 2 RNA polymerase I specific transcription initiation factor RRN3 Metallophos PF00149.23 ETO36162.1 - 2.1e-09 37.0 0.1 3.5e-09 36.3 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Vpu PF00558.14 ETO36162.1 - 0.13 11.8 2.0 0.23 11.0 1.4 1.4 1 0 0 1 1 1 0 Vpu protein MecA PF05389.7 ETO36163.1 - 3.3 7.1 9.7 0.056 12.9 0.8 2.0 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Myticin-prepro PF10690.4 ETO36164.1 - 0.19 11.7 2.2 0.21 11.6 0.3 1.9 2 0 0 2 2 2 0 Myticin pre-proprotein from the mussel WD40 PF00400.27 ETO36165.1 - 0.00016 21.4 2.1 0.00067 19.4 0.4 2.4 3 0 0 3 3 3 1 WD domain, G-beta repeat CHZ PF09649.5 ETO36165.1 - 0.15 11.2 1.6 0.23 10.7 1.1 1.3 1 0 0 1 1 1 0 Histone chaperone domain CHZ Methyltransf_11 PF08241.7 ETO36166.1 - 4.5e-15 55.9 0.1 2.4e-14 53.5 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETO36166.1 - 4.6e-13 48.8 0.0 7.3e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 ETO36166.1 - 4.7e-11 42.4 0.0 9.6e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETO36166.1 - 1.1e-07 32.0 0.0 2.1e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETO36166.1 - 5.5e-06 26.1 0.1 8.6e-06 25.5 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO36166.1 - 7.4e-05 23.1 0.0 0.00015 22.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO36166.1 - 0.0016 18.9 0.0 0.0051 17.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 ETO36166.1 - 0.035 13.3 0.1 0.25 10.5 0.0 2.1 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain UPF0020 PF01170.13 ETO36166.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 RhoGAP PF00620.22 ETO36167.1 - 1.4e-30 105.9 2.7 5e-30 104.1 0.0 2.4 2 0 0 2 2 2 1 RhoGAP domain Sulfotransfer_3 PF13469.1 ETO36168.1 - 3.4e-05 24.8 0.0 6.8e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase family zf-TRAF PF02176.13 ETO36169.1 - 0.00044 20.5 0.8 0.0012 19.1 0.1 2.1 2 0 0 2 2 2 1 TRAF-type zinc finger Choline_sulf_C PF12411.3 ETO36172.1 - 0.13 12.1 0.2 0.32 10.8 0.1 1.6 1 0 0 1 1 1 0 Choline sulfatase enzyme C terminal Cytochrom_C1 PF02167.10 ETO36173.1 - 7.3e-27 94.4 0.0 1.4e-26 93.5 0.0 1.4 2 0 0 2 2 2 1 Cytochrome C1 family TPR_12 PF13424.1 ETO36174.1 - 4e-06 26.6 0.0 6e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO36174.1 - 0.00036 20.0 1.3 0.00036 20.0 0.9 2.7 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO36174.1 - 0.00083 19.0 3.0 0.0048 16.7 0.3 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETO36174.1 - 0.0011 18.6 1.0 0.0051 16.4 0.7 2.1 1 1 1 2 2 2 1 TPR repeat TPR_10 PF13374.1 ETO36174.1 - 0.0012 18.7 0.2 0.0029 17.4 0.0 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO36174.1 - 0.021 14.9 0.4 0.032 14.3 0.3 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 ETO36174.1 - 0.25 11.2 6.3 2.8 7.9 0.4 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETO36175.1 - 6.4e-09 35.0 1.2 5.7e-05 22.5 0.2 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETO36175.1 - 7.3e-07 29.0 0.1 1.7e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETO36175.1 - 1.4e-06 27.7 0.4 0.007 16.2 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO36175.1 - 2.1e-06 27.3 0.5 4e-06 26.3 0.4 1.5 1 0 0 1 1 1 1 TPR repeat TPR_8 PF13181.1 ETO36175.1 - 5.9e-06 25.6 3.0 0.016 14.9 0.9 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO36175.1 - 2e-05 24.0 2.8 0.14 12.0 0.0 3.2 3 1 1 4 4 4 2 Tetratricopeptide repeat MIT PF04212.13 ETO36175.1 - 0.00043 20.0 1.0 0.31 10.9 0.2 2.4 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain Clathrin PF00637.15 ETO36175.1 - 0.03 13.9 1.0 0.069 12.7 0.4 1.7 1 1 0 1 1 1 0 Region in Clathrin and VPS TPR_17 PF13431.1 ETO36175.1 - 0.11 12.7 0.5 8.9 6.7 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat GxGYxYP PF14323.1 ETO36176.1 - 0.0059 15.3 0.3 0.011 14.5 0.2 1.4 1 0 0 1 1 1 1 GxGYxY sequence motif in domain of unknown function Baculo_PEP_C PF04513.7 ETO36176.1 - 0.085 12.6 1.3 0.69 9.7 0.2 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Acetyltransf_6 PF13480.1 ETO36176.1 - 0.2 11.6 2.4 0.31 11.0 0.0 2.4 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain DUF2937 PF11157.3 ETO36176.1 - 3.3 7.0 7.5 0.83 8.9 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2937) POPLD PF08170.7 ETO36177.1 - 0.12 12.2 2.5 1.2 9.0 0.7 2.6 2 0 0 2 2 2 0 POPLD (NUC188) domain Fer2 PF00111.22 ETO36178.1 - 9.4e-12 44.5 0.1 1.6e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain PH_3 PF14593.1 ETO36179.1 - 0.046 13.6 0.1 0.13 12.1 0.0 1.8 1 1 0 1 1 1 0 PH domain FLYWCH PF04500.11 ETO36179.1 - 3.6 7.5 7.7 2 8.3 0.4 3.0 2 1 1 3 3 3 0 FLYWCH zinc finger domain Streptin-Immun PF11083.3 ETO36180.1 - 0.03 14.2 11.3 0.047 13.6 7.8 1.3 1 0 0 1 1 1 0 Lantibiotic streptin immunity protein DUF3877 PF12993.2 ETO36180.1 - 0.079 12.5 3.8 0.095 12.2 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) DUF3450 PF11932.3 ETO36180.1 - 1.6 7.8 15.1 1.1 8.4 8.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TcdA_TcdB PF12919.2 ETO36180.1 - 2.2 6.6 7.2 2.3 6.5 5.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Cnd3 PF12719.2 ETO36181.1 - 4.2e-26 91.6 4.2 1.2e-25 90.1 2.9 1.8 1 1 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain H-kinase_dim PF02895.9 ETO36181.1 - 0.14 12.5 5.7 0.53 10.6 3.9 2.0 1 0 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain M_domain PF12938.2 ETO36181.1 - 3.2 7.5 13.3 0.027 14.2 2.7 2.1 2 0 0 2 2 2 0 M domain of GW182 DUF1104 PF06518.6 ETO36182.1 - 0.036 14.1 1.4 0.086 12.9 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) RRM_1 PF00076.17 ETO36183.1 - 0.00051 19.6 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) R-HINP1I PF11463.3 ETO36183.1 - 0.0048 16.3 0.2 0.0048 16.3 0.1 1.8 2 0 0 2 2 2 1 R.HinP1I restriction endonuclease 2OG-FeII_Oxy_2 PF13532.1 ETO36184.1 - 1.5e-20 73.9 0.7 1.9e-20 73.5 0.5 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HTH_31 PF13560.1 ETO36184.1 - 0.1 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain V_ATPase_I PF01496.14 ETO36185.1 - 7.3e-107 358.1 11.2 8.2e-107 357.9 7.7 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family V_ATPase_I PF01496.14 ETO36186.1 - 5.3e-51 173.3 0.1 6e-51 173.2 0.1 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Protocadherin PF08374.6 ETO36187.1 - 0.037 13.6 0.9 0.044 13.4 0.6 1.2 1 0 0 1 1 1 0 Protocadherin zf-MIZ PF02891.15 ETO36187.1 - 0.074 12.5 0.9 0.32 10.5 0.6 2.1 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C3HC4_2 PF13923.1 ETO36187.1 - 0.078 13.0 1.0 0.078 13.0 0.7 2.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SecY PF00344.15 ETO36187.1 - 0.081 11.8 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 SecY translocase DUF4512 PF14975.1 ETO36187.1 - 0.51 11.2 5.9 0.38 11.5 1.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) DHC PF09626.5 ETO36188.1 - 0.029 15.0 0.1 0.07 13.8 0.0 1.7 1 1 0 1 1 1 0 Dihaem cytochrome c WD40 PF00400.27 ETO36189.1 - 9.6e-24 82.3 24.0 4.3e-09 35.9 2.6 5.1 4 1 1 5 5 5 4 WD domain, G-beta repeat DUF1900 PF08954.6 ETO36189.1 - 0.004 16.6 0.0 3.5 7.1 0.0 3.0 1 1 2 3 3 3 2 Domain of unknown function (DUF1900) DUF1717 PF05414.6 ETO36189.1 - 0.0094 16.3 0.4 1.4 9.4 0.0 2.5 1 1 2 3 3 3 1 Viral domain of unknown function (DUF1717) Nup160 PF11715.3 ETO36189.1 - 0.01 14.0 2.6 0.041 12.0 0.1 2.4 1 1 0 2 2 2 0 Nucleoporin Nup120/160 DUF4221 PF13970.1 ETO36189.1 - 0.036 13.3 2.6 0.3 10.3 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4221) RHD3 PF05879.7 ETO36190.1 - 3.2e-07 28.7 1.6 4.9e-07 28.0 0.0 1.9 2 0 0 2 2 2 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 ETO36190.1 - 4.6e-07 29.1 3.2 7.7e-07 28.4 0.1 2.5 3 1 0 3 3 3 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 ETO36190.1 - 1.2e-06 28.4 0.1 3.4e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 ETO36190.1 - 3.3e-05 23.7 1.0 0.00047 20.0 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_16 PF13191.1 ETO36190.1 - 0.00054 20.0 0.0 0.0013 18.7 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 ETO36190.1 - 0.0016 19.2 0.5 0.11 13.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 ETO36190.1 - 0.014 15.9 0.3 0.054 14.0 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein AAA_14 PF13173.1 ETO36190.1 - 0.015 15.2 0.4 0.049 13.5 0.0 2.1 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 ETO36190.1 - 0.03 14.6 0.5 0.14 12.4 0.0 2.1 1 1 1 2 2 2 0 ABC transporter AAA_28 PF13521.1 ETO36190.1 - 0.042 13.8 0.8 0.12 12.3 0.1 2.1 3 0 0 3 3 3 0 AAA domain DAP3 PF10236.4 ETO36190.1 - 0.054 12.4 0.0 0.13 11.1 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 MobB PF03205.9 ETO36190.1 - 0.075 12.7 0.5 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 ETO36190.1 - 0.14 11.7 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 ETO36190.1 - 0.45 10.4 4.8 0.88 9.4 0.1 2.5 2 1 0 2 2 2 0 AAA domain zf-C3HC4_2 PF13923.1 ETO36191.1 - 0.0011 18.9 2.6 0.0076 16.2 1.8 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) YkyB PF14177.1 ETO36191.1 - 0.065 13.3 1.2 0.095 12.8 0.8 1.3 1 0 0 1 1 1 0 YkyB-like protein Tet_JBP PF12851.2 ETO36191.1 - 0.1 11.8 3.7 0.088 12.0 1.8 1.4 1 1 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily DUF1644 PF07800.7 ETO36191.1 - 0.35 10.7 12.9 14 5.5 8.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) Cys_knot PF00007.17 ETO36191.1 - 0.92 9.6 11.0 0.22 11.5 4.2 2.1 2 0 0 2 2 2 0 Cystine-knot domain zf-BED PF02892.10 ETO36191.1 - 1.4 8.7 5.4 1.3 8.7 0.1 2.8 3 0 0 3 3 3 0 BED zinc finger DUF1287 PF06940.6 ETO36192.1 - 0.048 13.0 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1287) Exo_endo_phos_2 PF14529.1 ETO36193.1 - 0.00071 19.1 0.3 0.0018 17.8 0.2 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase HSDR_N PF04313.9 ETO36193.1 - 0.016 14.9 3.0 0.028 14.1 2.1 1.4 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Dehydratase_SU PF02287.10 ETO36193.1 - 0.021 14.5 1.7 0.031 14.0 1.2 1.2 1 0 0 1 1 1 0 Dehydratase small subunit N6_N4_Mtase PF01555.13 ETO36193.1 - 0.023 14.1 2.5 0.029 13.8 1.7 1.2 1 0 0 1 1 1 0 DNA methylase UPF0180 PF03698.8 ETO36193.1 - 0.14 12.0 1.1 0.24 11.2 0.2 1.9 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0180) DUF812 PF05667.6 ETO36194.1 - 0.0035 15.9 2.9 0.0038 15.8 2.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF4094 PF13334.1 ETO36194.1 - 0.0089 16.3 5.5 0.013 15.9 3.8 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4094) DUF4618 PF15397.1 ETO36194.1 - 0.0091 15.3 5.3 0.01 15.2 3.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) Bromodomain PF00439.20 ETO36194.1 - 0.016 15.1 1.3 0.02 14.7 0.9 1.2 1 0 0 1 1 1 0 Bromodomain TSC22 PF01166.13 ETO36194.1 - 0.019 14.9 0.9 0.032 14.2 0.2 1.7 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF848 PF05852.6 ETO36194.1 - 0.045 13.6 3.3 0.049 13.4 2.3 1.1 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) TMEM51 PF15345.1 ETO36194.1 - 0.055 13.1 0.6 0.06 13.0 0.4 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 Fib_alpha PF08702.5 ETO36194.1 - 0.091 12.8 4.4 0.11 12.6 3.0 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF3573 PF12097.3 ETO36194.1 - 0.1 11.1 2.4 0.11 11.1 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Med9 PF07544.8 ETO36194.1 - 0.16 11.7 7.6 0.87 9.3 5.3 2.0 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Bap31 PF05529.7 ETO36194.1 - 0.29 10.5 3.9 0.39 10.1 2.7 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like FliD_N PF02465.13 ETO36194.1 - 0.4 11.0 5.9 0.2 12.0 2.5 1.6 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus bZIP_2 PF07716.10 ETO36194.1 - 0.45 10.3 5.8 1 9.2 4.0 1.7 1 1 0 1 1 1 0 Basic region leucine zipper ABC_tran_2 PF12848.2 ETO36194.1 - 1.3 8.9 5.8 0.33 10.8 1.7 1.6 1 1 1 2 2 2 0 ABC transporter DivIC PF04977.10 ETO36194.1 - 4 6.9 7.9 5 6.6 4.9 1.7 1 1 0 1 1 1 0 Septum formation initiator PFU PF09070.6 ETO36195.1 - 0.027 14.4 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) DUF2397 PF09660.5 ETO36196.1 - 0.011 14.3 0.0 0.011 14.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) Endonuc_Holl PF10107.4 ETO36196.1 - 0.038 13.6 2.6 0.046 13.4 1.8 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase SeqA PF03925.8 ETO36196.1 - 0.048 13.3 2.5 0.058 13.0 1.7 1.1 1 0 0 1 1 1 0 SeqA protein EMP24_GP25L PF01105.19 ETO36196.1 - 0.21 11.2 2.7 0.26 11.0 1.9 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Cytadhesin_P30 PF07271.6 ETO36196.1 - 0.26 10.5 2.3 0.25 10.5 1.6 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 Alg14 PF08660.6 ETO36196.1 - 0.27 11.2 1.7 0.31 11.0 1.2 1.0 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like DUF912 PF06024.7 ETO36196.1 - 0.4 10.7 2.4 0.48 10.5 1.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FlgM PF04316.8 ETO36196.1 - 0.51 10.3 3.7 0.71 9.8 2.4 1.5 1 1 0 1 1 1 0 Anti-sigma-28 factor, FlgM Spore_GerAC PF05504.6 ETO36196.1 - 2.4 7.9 9.7 3 7.6 6.7 1.1 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal HCaRG PF07258.9 ETO36197.1 - 4.8e-11 42.5 0.1 6.4e-11 42.1 0.1 1.2 1 0 0 1 1 1 1 HCaRG protein OB_RNB PF08206.6 ETO36197.1 - 0.06 12.8 0.1 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 Ribonuclease B OB domain WD40 PF00400.27 ETO36199.1 - 1.1e-10 40.8 0.1 2.3e-10 39.9 0.1 1.5 1 0 0 1 1 1 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO36199.1 - 0.092 10.8 0.0 0.12 10.5 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Lyase_aromatic PF00221.14 ETO36200.1 - 5.4e-172 572.4 0.0 6.6e-172 572.1 0.0 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase DERM PF14704.1 ETO36201.1 - 0.012 15.5 0.3 0.026 14.5 0.1 1.8 1 1 0 1 1 1 0 Dermatopontin DUF3450 PF11932.3 ETO36201.1 - 0.6 9.3 8.6 0.061 12.5 2.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) TLD PF07534.11 ETO36202.1 - 3.2e-10 40.1 0.1 5.7e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 TLD Sec3-PIP2_bind PF15277.1 ETO36202.1 - 0.033 14.0 0.6 0.87 9.5 0.2 2.8 2 1 0 2 2 2 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH CAP_GLY PF01302.20 ETO36203.1 - 9.8e-40 134.1 3.4 5.2e-21 74.1 0.1 2.3 2 0 0 2 2 2 2 CAP-Gly domain WD40 PF00400.27 ETO36205.1 - 5.6e-77 251.1 25.8 4.8e-13 48.4 0.3 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO36205.1 - 2.5e-08 33.8 3.1 0.00037 20.2 0.4 3.3 1 1 4 5 5 5 5 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 ETO36205.1 - 3.7e-05 23.3 0.2 0.0055 16.1 0.1 2.7 1 1 0 1 1 1 1 PQQ-like domain Nup160 PF11715.3 ETO36205.1 - 6.3e-05 21.3 8.5 0.1 10.6 0.1 4.9 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO36205.1 - 0.0057 14.9 1.3 3 6.0 0.0 2.9 1 1 1 3 3 3 2 Cytochrome D1 heme domain DUF1258 PF06869.7 ETO36205.1 - 0.006 15.7 8.0 0.25 10.3 0.4 3.4 2 1 2 4 4 4 2 Protein of unknown function (DUF1258) Coatomer_WDAD PF04053.9 ETO36205.1 - 0.008 15.0 5.3 0.51 9.0 0.1 3.1 1 1 0 2 2 2 2 Coatomer WD associated region Nucleoporin_N PF08801.6 ETO36205.1 - 0.021 13.5 12.2 0.44 9.2 0.6 4.3 1 1 2 3 3 3 0 Nup133 N terminal like PQQ PF01011.16 ETO36205.1 - 0.032 13.7 0.1 48 3.7 0.0 4.4 4 1 0 4 4 4 0 PQQ enzyme repeat FmdE PF02663.9 ETO36205.1 - 0.17 11.7 4.9 2.8 7.8 0.1 3.5 1 1 1 3 3 3 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Resistin PF06954.6 ETO36205.1 - 2.1 8.7 7.6 17 5.7 0.0 4.4 3 2 1 4 4 4 0 Resistin PD40 PF07676.7 ETO36205.1 - 2.4 7.8 8.0 27 4.5 0.0 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 ETO36206.1 - 4.2e-80 261.0 26.4 4.5e-14 51.6 0.3 7.4 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO36206.1 - 7.7e-11 40.8 7.7 0.0041 15.3 0.0 5.7 1 1 5 6 6 6 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO36206.1 - 1.5e-06 27.2 9.0 0.32 9.6 0.0 4.6 1 1 1 3 3 3 3 Nup133 N terminal like RicinB_lectin_2 PF14200.1 ETO36206.1 - 0.00017 21.9 0.1 0.0055 17.0 0.0 2.7 2 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 ETO36206.1 - 0.00046 20.2 5.0 0.97 9.4 0.8 3.7 1 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain IKI3 PF04762.7 ETO36206.1 - 0.00052 17.9 0.6 0.012 13.4 0.1 2.0 2 0 0 2 2 2 1 IKI3 family Cytochrom_D1 PF02239.11 ETO36206.1 - 0.00072 17.9 0.1 0.5 8.6 0.0 2.8 2 1 1 3 3 3 2 Cytochrome D1 heme domain DUF1258 PF06869.7 ETO36206.1 - 0.0014 17.7 4.2 0.26 10.3 0.1 3.0 1 1 1 3 3 3 2 Protein of unknown function (DUF1258) DUF727 PF05303.7 ETO36206.1 - 0.013 15.3 0.7 21 4.9 0.0 3.6 2 2 1 3 3 3 0 Protein of unknown function (DUF727) PD40 PF07676.7 ETO36206.1 - 0.033 13.8 0.1 23 4.7 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO36206.1 - 0.067 12.6 0.0 0.48 9.8 0.0 2.3 1 1 0 1 1 1 0 PQQ-like domain USP7_C2 PF14533.1 ETO36206.1 - 0.11 11.8 0.2 40 3.5 0.0 3.6 2 1 2 4 4 4 0 Ubiquitin-specific protease C-terminal CathepsinC_exc PF08773.6 ETO36206.1 - 0.15 12.2 1.7 0.74 9.9 0.0 2.9 2 1 1 3 3 3 0 Cathepsin C exclusion domain TauE PF01925.14 ETO36207.1 - 1.7e-16 60.4 6.9 8e-10 38.5 0.0 2.4 3 0 0 3 3 3 2 Sulfite exporter TauE/SafE CTD_bind PF04818.8 ETO36209.1 - 0.11 12.7 0.9 0.5 10.6 0.2 2.3 2 0 0 2 2 2 0 RNA polymerase II-binding domain. Exo_endo_phos PF03372.18 ETO36211.1 - 8.3e-10 39.0 0.0 1.6e-09 38.0 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RsgI_N PF12791.2 ETO36211.1 - 0.078 12.6 0.2 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 Anti-sigma factor N-terminus DUF1625 PF07787.7 ETO36212.1 - 0.0014 17.9 0.0 0.0026 17.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1625) CsgE PF10627.4 ETO36212.1 - 0.021 14.6 0.1 0.046 13.5 0.1 1.5 1 0 0 1 1 1 0 Curli assembly protein CsgE Mcp5_PH PF12814.2 ETO36212.1 - 0.047 13.6 0.1 0.13 12.1 0.1 1.8 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology AXH PF08517.7 ETO36212.1 - 0.078 13.1 0.1 0.2 11.8 0.1 1.7 1 0 0 1 1 1 0 Ataxin-1 and HBP1 module (AXH) DENN PF02141.16 ETO36213.1 - 0.003 17.3 0.0 0.0051 16.5 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain zf-DHHC PF01529.15 ETO36214.1 - 5.2e-30 104.1 0.9 5.2e-30 104.1 0.6 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase DZR PF12773.2 ETO36214.1 - 0.12 12.1 4.6 0.24 11.2 3.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon MIB_HERC2 PF06701.8 ETO36215.1 - 4.9e-30 103.2 21.5 2.9e-20 72.0 1.9 4.9 5 0 0 5 5 5 4 Mib_herc2 UBA PF00627.26 ETO36215.1 - 0.054 13.3 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain Atrophin-1 PF03154.10 ETO36215.1 - 4.8 5.1 6.9 6.4 4.7 4.8 1.0 1 0 0 1 1 1 0 Atrophin-1 family Pox_Ag35 PF03286.9 ETO36216.1 - 8.2e-05 22.2 9.9 0.00011 21.7 6.9 1.3 1 0 0 1 1 1 1 Pox virus Ag35 surface protein Nop14 PF04147.7 ETO36216.1 - 0.00084 17.3 15.5 0.00097 17.1 10.7 1.1 1 0 0 1 1 1 1 Nop14-like family SAM_PNT PF02198.11 ETO36216.1 - 0.0056 16.4 0.2 0.0098 15.6 0.2 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_2 PF07647.12 ETO36216.1 - 0.01 15.6 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF2052 PF09747.4 ETO36216.1 - 0.014 15.3 17.5 0.027 14.4 12.1 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) YABBY PF04690.8 ETO36216.1 - 0.031 14.5 4.5 0.051 13.8 3.1 1.3 1 0 0 1 1 1 0 YABBY protein Zip PF02535.17 ETO36216.1 - 0.035 13.1 3.0 0.039 12.9 2.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SAM_1 PF00536.25 ETO36216.1 - 0.039 14.1 0.0 0.079 13.1 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Ycf1 PF05758.7 ETO36216.1 - 0.12 10.0 13.7 0.15 9.7 9.5 1.1 1 0 0 1 1 1 0 Ycf1 TFIIF_alpha PF05793.7 ETO36216.1 - 0.13 10.6 22.7 0.16 10.2 15.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Daxx PF03344.10 ETO36216.1 - 0.13 10.7 21.5 0.15 10.4 14.9 1.1 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 ETO36216.1 - 0.18 11.1 24.2 0.29 10.4 16.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SAPS PF04499.10 ETO36216.1 - 0.18 10.3 9.3 0.2 10.2 6.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FAM60A PF15396.1 ETO36216.1 - 0.39 10.4 9.7 0.62 9.7 6.7 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Bud13 PF09736.4 ETO36216.1 - 0.41 10.9 21.7 0.054 13.7 12.1 1.7 2 0 0 2 2 1 0 Pre-mRNA-splicing factor of RES complex U79_P34 PF03064.11 ETO36216.1 - 0.41 10.1 15.3 0.67 9.4 10.6 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DDRGK PF09756.4 ETO36216.1 - 0.64 9.3 27.3 1.2 8.5 18.9 1.4 1 0 0 1 1 1 0 DDRGK domain Tim54 PF11711.3 ETO36216.1 - 0.67 8.4 13.2 1.1 7.7 9.2 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF262 PF03235.9 ETO36216.1 - 0.7 9.8 6.9 0.12 12.3 2.3 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF262 DUF853 PF05872.7 ETO36216.1 - 0.71 8.1 6.4 0.78 8.0 4.4 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) MFMR PF07777.6 ETO36216.1 - 0.87 9.4 9.1 1.8 8.4 6.3 1.5 1 0 0 1 1 1 0 G-box binding protein MFMR CDC45 PF02724.9 ETO36216.1 - 0.89 7.5 16.1 1.1 7.1 11.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Atrophin-1 PF03154.10 ETO36216.1 - 1 7.4 12.7 1.2 7.1 8.8 1.2 1 0 0 1 1 1 0 Atrophin-1 family SOBP PF15279.1 ETO36216.1 - 1.1 9.5 9.8 1.5 9.1 6.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Vfa1 PF08432.5 ETO36216.1 - 1.3 9.0 25.9 2.5 8.0 17.9 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 GAGA_bind PF06217.7 ETO36216.1 - 2 8.3 11.9 2.9 7.7 8.3 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family RP-C_C PF11800.3 ETO36216.1 - 2.1 7.9 12.0 88 2.7 8.8 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region Spore_coat_CotO PF14153.1 ETO36216.1 - 2.3 7.6 23.7 0.5 9.7 14.0 1.7 2 0 0 2 2 2 0 Spore coat protein CotO NARP1 PF12569.3 ETO36216.1 - 2.3 6.8 20.0 3.7 6.2 13.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Sec62 PF03839.11 ETO36216.1 - 2.7 7.3 15.2 4.2 6.7 10.5 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 RNA_polI_A34 PF08208.6 ETO36216.1 - 2.9 7.5 25.9 4.8 6.8 17.9 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RR_TM4-6 PF06459.7 ETO36216.1 - 3.5 7.4 22.2 5.5 6.8 15.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.7 ETO36216.1 - 4.1 6.0 9.3 5.3 5.6 6.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TEX19 PF15553.1 ETO36216.1 - 4.9 6.9 10.3 4.2 7.2 5.0 2.1 2 0 0 2 2 2 0 Testis-expressed protein 19 Neur_chan_memb PF02932.11 ETO36216.1 - 8.2 6.2 8.5 12 5.7 5.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region YqfQ PF14181.1 ETO36216.1 - 8.4 6.4 20.4 15 5.5 14.1 1.5 1 0 0 1 1 1 0 YqfQ-like protein FLO_LFY PF01698.11 ETO36216.1 - 8.7 5.0 16.0 13 4.4 11.1 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Cellulose_synt PF03552.9 ETO36216.1 - 8.9 4.4 9.3 12 4.0 6.5 1.1 1 0 0 1 1 1 0 Cellulose synthase zf-C3HC4_3 PF13920.1 ETO36218.1 - 1.8e-09 37.1 6.7 1.8e-09 37.1 4.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO36218.1 - 0.00013 21.9 8.9 0.00013 21.9 6.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.9 ETO36218.1 - 0.0019 17.6 7.4 0.0027 17.1 2.5 3.1 3 0 0 3 3 3 1 P-11 zinc finger zf-RING_5 PF14634.1 ETO36218.1 - 0.0035 17.0 10.5 0.0035 17.0 7.3 2.4 2 1 0 2 2 2 1 zinc-RING finger domain Tudor-knot PF11717.3 ETO36218.1 - 0.0041 16.8 1.0 0.01 15.5 0.7 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-RING_2 PF13639.1 ETO36218.1 - 0.0062 16.3 12.7 0.067 13.0 8.9 2.6 1 1 1 2 2 2 1 Ring finger domain PhyH PF05721.8 ETO36220.1 - 0.00064 19.8 0.1 0.064 13.2 0.0 2.8 3 0 0 3 3 3 2 Phytanoyl-CoA dioxygenase (PhyH) FGF PF00167.13 ETO36220.1 - 0.029 14.1 0.5 0.086 12.6 0.4 1.9 1 0 0 1 1 1 0 Fibroblast growth factor EF-hand_7 PF13499.1 ETO36224.1 - 8.8e-22 77.0 11.7 8.9e-11 41.7 1.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 ETO36224.1 - 8.1e-18 62.3 12.3 2.1e-05 23.4 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 ETO36224.1 - 5.5e-17 60.0 5.9 0.00045 19.8 0.0 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 ETO36224.1 - 1.3e-12 47.1 9.9 1.8e-09 37.0 1.1 2.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.1 ETO36224.1 - 3e-11 43.0 1.0 0.00013 21.8 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 ETO36224.1 - 8.2e-06 24.9 4.9 0.8 9.1 0.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.2 ETO36224.1 - 0.13 12.0 8.1 1.4 8.6 0.3 2.7 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand ATP-cone PF03477.11 ETO36224.1 - 1.3 9.4 5.7 6.3 7.3 0.3 3.0 2 1 1 3 3 3 0 ATP cone domain PH PF00169.24 ETO36225.1 - 4.2e-18 65.4 1.4 1.2e-17 63.9 0.1 2.0 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 ETO36225.1 - 2.3e-06 27.8 2.7 2.8e-05 24.3 1.9 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 ETO36225.1 - 2.5e-05 24.0 0.0 4.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 ETO36225.1 - 0.014 15.4 0.1 0.032 14.2 0.1 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Nit_Regul_Hom PF10126.4 ETO36226.1 - 0.51 10.1 3.9 0.43 10.3 0.5 2.6 2 1 0 3 3 3 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII RVT_1 PF00078.22 ETO36228.1 - 0.0048 16.2 0.1 3.1 7.1 0.0 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L6e PF01159.14 ETO36229.1 - 0.33 11.1 3.7 1.3 9.2 2.6 2.0 1 1 0 1 1 1 0 Ribosomal protein L6e PrmA PF06325.8 ETO36230.1 - 7e-05 22.0 0.0 0.00012 21.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 ETO36230.1 - 0.00018 21.3 0.0 0.00045 19.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO36230.1 - 0.0024 18.4 0.5 0.0076 16.8 0.1 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETO36230.1 - 0.0033 17.0 2.0 0.0041 16.7 0.1 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETO36230.1 - 0.0057 16.6 0.1 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETO36230.1 - 0.029 13.7 0.1 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.7 ETO36230.1 - 0.052 14.0 0.1 0.12 12.8 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.6 ETO36230.1 - 0.053 12.2 0.0 0.079 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.4 ETO36230.1 - 0.072 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase PRMT5 PF05185.11 ETO36231.1 - 3.2e-05 23.0 0.2 4.1e-05 22.7 0.1 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PHD PF00628.24 ETO36232.1 - 0.051 13.2 2.1 0.12 12.1 1.4 1.5 1 0 0 1 1 1 0 PHD-finger Phlebovirus_G1 PF07243.6 ETO36232.1 - 0.058 11.5 1.2 0.078 11.1 0.8 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 PTPlike_phytase PF14566.1 ETO36233.1 - 3.4e-18 66.1 0.2 5.4e-17 62.2 0.0 2.4 2 1 0 2 2 2 1 Inositol hexakisphosphate Pox_G5 PF04599.7 ETO36233.1 - 0.0085 14.8 0.1 0.011 14.5 0.1 1.1 1 0 0 1 1 1 1 Poxvirus G5 protein Cnd1_N PF12922.2 ETO36233.1 - 0.01 15.4 1.4 0.013 15.0 0.4 1.6 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term WD40 PF00400.27 ETO36234.1 - 4.7e-46 153.0 11.8 1.9e-12 46.5 0.1 6.7 6 1 1 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO36234.1 - 4.1e-08 33.1 0.2 0.0062 16.2 0.0 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO36234.1 - 3.5e-05 22.1 3.2 0.04 12.0 0.3 3.1 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Str_synth PF03088.11 ETO36234.1 - 6e-05 23.0 0.2 4.5 7.3 0.0 4.1 3 1 1 4 4 4 2 Strictosidine synthase B_lectin PF01453.19 ETO36234.1 - 0.0011 18.8 3.8 1.5 8.7 0.1 3.4 2 1 2 4 4 4 2 D-mannose binding lectin PD40 PF07676.7 ETO36234.1 - 0.0012 18.5 2.1 37 4.1 0.0 5.3 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO36234.1 - 0.0036 15.6 0.1 1.4 7.1 0.0 3.0 2 1 1 3 3 3 1 Cytochrome D1 heme domain NodS PF05401.6 ETO36234.1 - 0.012 15.0 0.1 4.4 6.6 0.0 2.9 3 0 0 3 3 3 0 Nodulation protein S (NodS) Resistin PF06954.6 ETO36234.1 - 0.14 12.4 0.3 3.9 7.8 0.0 2.8 1 1 2 3 3 3 0 Resistin Ank_4 PF13637.1 ETO36235.1 - 4.6e-12 46.0 0.0 1.5e-11 44.4 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 ETO36235.1 - 2.6e-11 42.7 0.5 1.7e-07 30.6 0.1 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 ETO36235.1 - 5.9e-11 42.5 0.2 2.2e-10 40.7 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETO36235.1 - 1.8e-10 40.6 0.5 2.8e-05 24.1 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO36235.1 - 5.1e-05 23.1 0.2 0.0053 16.8 0.1 3.4 2 0 0 2 2 2 1 Ankyrin repeat Arm PF00514.18 ETO36235.1 - 0.00011 21.9 0.7 0.02 14.7 0.1 3.3 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat SNF5 PF04855.7 ETO36238.1 - 9.5e-14 51.4 0.5 1.2e-13 51.1 0.3 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 WD40 PF00400.27 ETO36240.1 - 1.5e-10 40.5 6.7 4.7e-05 23.0 0.1 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat PhoU PF01895.14 ETO36240.1 - 0.047 14.1 1.1 0.12 12.8 0.7 1.6 1 0 0 1 1 1 0 PhoU domain Nop14 PF04147.7 ETO36241.1 - 6.9e-06 24.2 43.6 6.9e-06 24.2 30.2 2.1 2 0 0 2 2 2 1 Nop14-like family DUF2457 PF10446.4 ETO36241.1 - 4.9e-05 22.2 47.3 7.7e-05 21.6 32.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) SDA1 PF05285.7 ETO36241.1 - 0.00026 20.4 48.7 0.00044 19.6 33.7 1.3 1 0 0 1 1 1 1 SDA1 Kelch_6 PF13964.1 ETO36241.1 - 0.0073 16.4 1.7 0.23 11.7 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.20 ETO36241.1 - 0.26 10.8 1.3 0.9 9.1 0.1 2.6 3 0 0 3 3 3 0 Kelch motif CENP-T PF15511.1 ETO36241.1 - 0.4 9.8 31.2 0.62 9.2 21.6 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CDC45 PF02724.9 ETO36241.1 - 0.47 8.4 43.9 0.98 7.3 30.5 1.4 1 0 0 1 1 1 0 CDC45-like protein Mem_trans PF03547.13 ETO36241.1 - 2.1 6.5 3.9 2.6 6.2 2.7 1.2 1 0 0 1 1 1 0 Membrane transport protein DUF1777 PF08648.7 ETO36242.1 - 2.5 7.8 95.5 0.085 12.5 40.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1777) WD40 PF00400.27 ETO36243.1 - 5.1e-76 248.0 7.9 1.9e-11 43.3 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO36243.1 - 1.7e-07 29.8 1.4 0.11 10.5 0.1 4.2 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO36243.1 - 6.2e-07 28.5 9.4 0.023 13.4 0.3 5.0 1 1 2 4 4 4 3 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO36243.1 - 1.8e-06 26.5 0.2 0.012 13.9 0.0 2.9 1 1 2 3 3 3 3 Cytochrome D1 heme domain Str_synth PF03088.11 ETO36243.1 - 0.0023 17.9 0.3 0.95 9.5 0.0 3.3 2 2 0 2 2 2 1 Strictosidine synthase PQQ_2 PF13360.1 ETO36243.1 - 0.021 14.2 0.0 0.2 11.1 0.0 2.6 1 1 0 1 1 1 0 PQQ-like domain Resistin PF06954.6 ETO36243.1 - 0.024 14.9 0.1 23 5.3 0.0 4.0 4 2 0 4 4 4 0 Resistin PD40 PF07676.7 ETO36243.1 - 0.056 13.1 0.2 40 4.0 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Ras PF00071.17 ETO36244.1 - 2.3e-32 111.6 0.0 2.3e-15 56.3 0.0 2.5 2 1 0 2 2 2 2 Ras family Miro PF08477.8 ETO36244.1 - 5e-10 39.9 0.0 6.9e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein AAA_24 PF13479.1 ETO36244.1 - 0.0079 15.7 0.1 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain TIMELESS_C PF05029.8 ETO36245.1 - 0.016 14.1 16.6 0.03 13.2 11.5 1.4 1 0 0 1 1 1 0 Timeless protein C terminal region NYAP_N PF15439.1 ETO36245.1 - 0.11 11.6 9.3 0.23 10.6 6.5 1.4 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter SEEEED PF14797.1 ETO36245.1 - 0.3 11.2 36.7 0.51 10.4 25.4 1.3 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex CDC45 PF02724.9 ETO36245.1 - 0.83 7.6 17.6 0.026 12.5 7.7 1.8 2 0 0 2 2 2 0 CDC45-like protein Kelch_3 PF13415.1 ETO36246.1 - 0.00038 20.5 0.0 0.0013 18.8 0.0 1.8 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_4 PF13418.1 ETO36246.1 - 0.00069 19.3 0.9 0.002 17.8 0.0 2.3 3 1 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO36246.1 - 0.0018 17.7 0.0 0.0032 16.9 0.0 1.3 1 0 0 1 1 1 1 Kelch motif Kelch_6 PF13964.1 ETO36246.1 - 0.0025 17.9 0.8 0.03 14.5 0.0 2.8 1 1 1 3 3 3 1 Kelch motif Kelch_6 PF13964.1 ETO36247.1 - 0.031 14.4 0.4 3.2 8.0 0.0 3.4 4 0 0 4 4 4 0 Kelch motif Kelch_1 PF01344.20 ETO36247.1 - 0.16 11.5 0.7 1.4 8.5 0.0 2.7 3 0 0 3 3 3 0 Kelch motif Exo_endo_phos_2 PF14529.1 ETO36248.1 - 0.057 13.0 1.0 0.13 11.8 0.2 1.9 1 1 0 2 2 2 0 Endonuclease-reverse transcriptase NACHT PF05729.7 ETO36249.1 - 0.0013 18.3 0.0 0.0042 16.7 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.1 ETO36249.1 - 0.0018 18.5 0.3 0.019 15.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETO36249.1 - 0.0042 17.2 0.0 0.012 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETO36249.1 - 0.0095 16.7 0.0 0.061 14.1 0.0 2.4 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 ETO36249.1 - 0.014 14.5 0.8 0.39 9.7 0.0 2.9 3 0 0 3 3 3 0 KaiC AAA_10 PF12846.2 ETO36249.1 - 0.02 14.3 1.1 3.8 6.8 0.2 2.6 2 0 0 2 2 2 0 AAA-like domain AAA_29 PF13555.1 ETO36249.1 - 0.13 11.8 0.1 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain WD40 PF00400.27 ETO36250.1 - 1.7e-05 24.4 0.8 8.9e-05 22.2 0.2 2.2 3 0 0 3 3 3 1 WD domain, G-beta repeat UpxZ PF06603.6 ETO36250.1 - 0.024 14.6 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 UpxZ family of transcription anti-terminator antagonists Nup160 PF11715.3 ETO36250.1 - 0.16 10.0 0.0 0.17 10.0 0.0 1.0 1 0 0 1 1 1 0 Nucleoporin Nup120/160 WD40 PF00400.27 ETO36251.1 - 7.1e-14 51.0 0.4 6.7e-10 38.4 0.0 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat Josephin PF02099.12 ETO36252.1 - 1.5e-14 53.9 6.0 1.7e-07 30.9 0.2 2.5 1 1 1 2 2 2 2 Josephin Dala_Dala_lig_N PF01820.16 ETO36252.1 - 0.091 13.0 0.4 0.33 11.2 0.2 2.0 1 1 2 3 3 3 0 D-ala D-ala ligase N-terminus zf-C2H2 PF00096.21 ETO36253.1 - 0.0036 17.5 5.9 0.0089 16.3 0.2 3.5 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETO36253.1 - 0.0051 17.0 4.3 0.025 14.9 0.2 3.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_6 PF13912.1 ETO36253.1 - 0.012 15.4 0.4 0.012 15.4 0.3 2.3 3 0 0 3 3 3 0 C2H2-type zinc finger Mito_fiss_reg PF05308.6 ETO36253.1 - 0.71 9.1 6.7 1.6 8.0 4.4 1.9 1 1 0 1 1 1 0 Mitochondrial fission regulator zf-H2C2_2 PF13465.1 ETO36253.1 - 3.6 8.0 23.6 0.56 10.5 0.5 3.5 4 0 0 4 4 4 0 Zinc-finger double domain DUF2730 PF10805.3 ETO36254.1 - 0.0091 15.7 0.2 0.018 14.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) Ribosomal_S3_C PF00189.15 ETO36254.1 - 0.015 15.4 3.7 0.28 11.4 2.2 2.2 2 0 0 2 2 2 0 Ribosomal protein S3, C-terminal domain Glucosaminidase PF01832.15 ETO36254.1 - 0.044 13.8 0.3 0.24 11.5 0.0 2.1 1 1 1 2 2 2 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Erp_C PF06780.6 ETO36254.1 - 0.34 10.7 6.7 0.67 9.7 1.8 2.3 1 1 1 2 2 2 0 Erp protein C-terminus WD40 PF00400.27 ETO36256.1 - 4.2e-56 184.9 10.5 1.1e-09 37.7 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nbas_N PF15492.1 ETO36256.1 - 0.052 12.6 0.0 8.6 5.3 0.0 2.7 3 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Aminotran_4 PF01063.14 ETO36257.1 - 7e-19 68.2 0.0 1.3e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class IV SAYSvFN PF10260.4 ETO36258.1 - 2.2e-20 72.1 3.0 3.2e-20 71.6 2.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) SEC-C PF02810.10 ETO36258.1 - 3.3e-08 32.8 11.0 4.9e-08 32.3 7.6 1.3 1 0 0 1 1 1 1 SEC-C motif DUF2804 PF10974.3 ETO36258.1 - 0.017 13.9 0.1 0.023 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2804) Kelch_4 PF13418.1 ETO36260.1 - 2.5e-06 27.1 1.6 0.0054 16.4 0.0 3.5 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO36260.1 - 5.3e-06 25.9 1.0 0.011 15.4 0.0 4.4 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 ETO36260.1 - 3.6e-05 23.7 5.2 0.93 9.7 0.3 4.9 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 ETO36260.1 - 0.00019 21.3 0.3 0.66 9.9 0.4 4.7 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.20 ETO36260.1 - 0.0012 18.2 5.4 0.01 15.3 0.1 4.1 4 0 0 4 4 4 1 Kelch motif QRPTase_N PF02749.11 ETO36261.1 - 3.8e-26 90.7 0.0 5.3e-26 90.2 0.0 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Biotin_lipoyl PF00364.17 ETO36261.1 - 0.036 13.6 0.0 0.1 12.2 0.0 1.8 1 1 0 1 1 1 0 Biotin-requiring enzyme PYNP_C PF07831.8 ETO36261.1 - 0.11 12.0 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain WD40 PF00400.27 ETO36262.1 - 4.3e-07 29.5 0.0 0.07 13.0 0.0 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat DBINO PF13892.1 ETO36262.1 - 0.012 15.6 10.7 0.02 14.9 7.4 1.3 1 0 0 1 1 1 0 DNA-binding domain MvaI_BcnI PF15515.1 ETO36263.1 - 0.12 12.3 0.1 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 MvaI/BcnI restriction endonuclease family DUF1162 PF06650.7 ETO36264.1 - 8.8e-28 97.2 1.0 3.5e-27 95.3 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1162) C2 PF00168.25 ETO36264.1 - 1.4e-14 53.6 0.2 5.6e-14 51.7 0.0 2.3 2 0 0 2 2 2 1 C2 domain ATG_C PF09333.6 ETO36264.1 - 1.1e-06 28.7 0.1 4e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 ATG C terminal domain RabGAP-TBC PF00566.13 ETO36266.1 - 0.0093 15.4 0.1 0.011 15.1 0.1 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Phage_Gp23 PF10669.4 ETO36266.1 - 0.29 11.2 4.5 0.42 10.7 3.2 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DUF2422 PF10337.4 ETO36266.1 - 0.76 8.5 3.8 0.33 9.6 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) WD40 PF00400.27 ETO36269.1 - 5.7e-84 273.2 17.2 2.2e-11 43.1 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO36269.1 - 3.8e-07 28.6 3.7 0.21 9.6 0.0 5.4 1 1 5 6 6 6 3 Nucleoporin Nup120/160 Nbas_N PF15492.1 ETO36269.1 - 0.00018 20.7 1.2 0.98 8.4 0.0 4.2 3 1 0 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Kelch_6 PF13964.1 ETO36269.1 - 0.00027 20.9 1.3 0.17 12.1 0.1 4.1 3 0 0 3 3 3 1 Kelch motif PD40 PF07676.7 ETO36269.1 - 0.00039 20.0 8.3 5.5 6.7 0.0 5.5 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 ETO36269.1 - 0.0023 16.7 11.0 0.12 11.1 2.8 4.3 1 1 2 3 3 3 2 Nup133 N terminal like B_lectin PF01453.19 ETO36269.1 - 0.0033 17.3 0.2 0.51 10.2 0.1 2.9 1 1 0 2 2 2 1 D-mannose binding lectin Kelch_4 PF13418.1 ETO36269.1 - 0.0084 15.8 0.0 1.4 8.7 0.0 3.2 2 0 0 2 2 2 1 Galactose oxidase, central domain NodS PF05401.6 ETO36269.1 - 0.0091 15.4 0.2 0.56 9.5 0.0 3.3 4 0 0 4 4 4 1 Nodulation protein S (NodS) Kelch_1 PF01344.20 ETO36269.1 - 0.0098 15.4 2.4 0.018 14.5 0.2 2.5 2 0 0 2 2 2 1 Kelch motif PQQ_2 PF13360.1 ETO36269.1 - 0.071 12.5 0.0 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 PQQ-like domain Resistin PF06954.6 ETO36269.1 - 0.072 13.3 0.0 50 4.2 0.0 4.4 2 2 3 5 5 5 0 Resistin Kelch_2 PF07646.10 ETO36269.1 - 0.086 12.6 1.0 2.8 7.8 0.0 3.8 4 0 0 4 4 4 0 Kelch motif Proteasome_A_N PF10584.4 ETO36269.1 - 0.84 9.0 5.9 92 2.4 0.0 4.9 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature YMF19 PF02326.10 ETO36270.1 - 0.19 12.2 0.3 0.19 12.2 0.2 4.1 2 2 3 5 5 5 0 Plant ATP synthase F0 QRPTase_C PF01729.14 ETO36271.1 - 8.6e-49 165.3 7.6 1.1e-41 142.2 1.9 2.0 1 1 1 2 2 2 2 Quinolinate phosphoribosyl transferase, C-terminal domain WD40 PF00400.27 ETO36273.1 - 2.2e-10 40.0 0.2 8.6e-10 38.1 0.1 1.9 2 0 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO36273.1 - 0.031 12.4 0.0 0.032 12.3 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DUF2701 PF10857.3 ETO36274.1 - 3.6 7.4 5.8 3.4 7.5 0.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2701) PH_4 PF15404.1 ETO36275.1 - 0.017 14.6 4.7 0.14 11.6 1.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain SpoIISB_antitox PF14185.1 ETO36275.1 - 0.026 14.2 0.1 0.026 14.2 0.1 2.8 4 0 0 4 4 4 0 Antitoxin SpoIISB, type II toxin-antitoxin system DUF3701 PF12482.3 ETO36276.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Phage integrase protein DM PF00751.13 ETO36277.1 - 0.021 14.3 1.7 0.039 13.4 1.2 1.5 1 0 0 1 1 1 0 DM DNA binding domain Secretin_N_2 PF07655.8 ETO36277.1 - 0.057 13.8 8.5 0.094 13.1 5.9 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Transposase_21 PF02992.9 ETO36277.1 - 0.085 11.9 9.9 0.06 12.4 4.9 1.7 1 1 1 2 2 2 0 Transposase family tnp2 CobT PF06213.7 ETO36277.1 - 0.2 10.7 5.1 0.25 10.4 3.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FYVE PF01363.16 ETO36277.1 - 0.52 10.2 5.8 0.95 9.4 4.0 1.5 1 1 0 1 1 1 0 FYVE zinc finger Peptidase_S49_N PF08496.5 ETO36277.1 - 0.68 9.7 4.0 1 9.1 2.8 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Zip PF02535.17 ETO36277.1 - 0.84 8.5 3.0 0.85 8.5 2.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF912 PF06024.7 ETO36277.1 - 0.86 9.6 6.7 1.4 8.9 4.6 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Ceramidase PF05875.7 ETO36278.1 - 2.3e-09 36.7 25.2 2.3e-09 36.7 17.5 2.4 2 1 0 2 2 2 1 Ceramidase zf-UBR PF02207.15 ETO36279.1 - 1.4e-18 66.4 13.4 2.8e-18 65.3 9.3 1.6 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) DUF2014 PF09427.5 ETO36279.1 - 0.032 13.3 0.1 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2014) TB2_DP1_HVA22 PF03134.14 ETO36281.1 - 3.2e-05 23.5 6.6 3.2e-05 23.5 4.5 4.2 3 1 1 4 4 4 2 TB2/DP1, HVA22 family Rnk_N PF14760.1 ETO36282.1 - 0.0012 18.8 0.1 0.0024 17.8 0.1 1.6 1 0 0 1 1 1 1 Rnk N-terminus Phasin PF05597.6 ETO36282.1 - 0.013 15.2 3.4 0.013 15.2 2.4 1.9 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Cytochrom_C_2 PF01322.15 ETO36282.1 - 0.054 14.0 0.0 1.8 9.0 0.1 2.1 2 0 0 2 2 2 0 Cytochrome C' CALCOCO1 PF07888.6 ETO36282.1 - 0.12 10.6 8.0 0.11 10.8 3.6 1.8 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like SPT16 PF08644.6 ETO36282.1 - 0.12 12.1 7.2 0.13 12.1 4.3 1.6 1 1 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) DUF4455 PF14643.1 ETO36282.1 - 0.68 8.4 11.4 0.083 11.5 4.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4455) BING4CT PF08149.6 ETO36282.1 - 1 8.8 6.3 11 5.6 1.4 2.4 2 0 0 2 2 2 0 BING4CT (NUC141) domain Tnp_P_element PF12017.3 ETO36282.1 - 2.5 7.2 8.8 0.89 8.7 3.2 1.9 2 0 0 2 2 2 0 Transposase protein GrpE PF01025.14 ETO36282.1 - 3.3 7.2 11.4 9.5 5.7 7.9 1.9 1 1 0 1 1 1 0 GrpE GAF PF01590.21 ETO36283.1 - 1e-18 67.8 0.0 3.8e-09 36.8 0.0 3.1 3 0 0 3 3 3 3 GAF domain GAF_3 PF13492.1 ETO36283.1 - 5e-13 49.2 0.0 2e-06 27.9 0.0 2.3 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.1 ETO36283.1 - 1.3e-06 28.9 0.0 0.013 15.9 0.0 2.9 3 0 0 3 3 3 2 GAF domain Phage_hub_GP28 PF11110.3 ETO36283.1 - 0.021 14.5 0.4 0.055 13.1 0.0 1.8 2 0 0 2 2 2 0 Baseplate hub distal subunit Med22 PF06179.7 ETO36284.1 - 5.3e-05 23.2 4.1 0.0002 21.3 2.8 1.8 1 1 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex DUF870 PF05912.6 ETO36284.1 - 0.066 13.0 0.2 1.6 8.5 0.0 2.1 2 0 0 2 2 2 0 Caenorhabditis elegans protein of unknown function (DUF870) SAGA-Tad1 PF12767.2 ETO36285.1 - 0.0094 15.6 10.6 0.011 15.4 7.3 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Asp-B-Hydro_N PF05279.6 ETO36285.1 - 0.05 13.4 20.0 0.056 13.2 13.9 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region MIP-T3 PF10243.4 ETO36285.1 - 0.33 9.3 35.9 0.4 9.1 24.9 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Gag_spuma PF03276.9 ETO36285.1 - 0.53 8.5 3.4 0.63 8.3 2.3 1.2 1 0 0 1 1 1 0 Spumavirus gag protein DUF1510 PF07423.6 ETO36285.1 - 1.1 8.6 26.6 1.3 8.2 18.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2201_N PF13203.1 ETO36285.1 - 1.1 8.3 11.1 1.4 7.9 7.7 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Dsh_C PF12316.3 ETO36285.1 - 1.1 9.3 6.6 1.4 8.9 4.6 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Dehalogenase PF13486.1 ETO36285.1 - 1.2 8.5 9.8 1.6 8.0 6.8 1.1 1 0 0 1 1 1 0 Reductive dehalogenase subunit DUF936 PF06075.7 ETO36285.1 - 3.6 6.3 18.1 4.5 6.0 12.6 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Bud13 PF09736.4 ETO36285.1 - 3.6 7.8 24.6 4.5 7.5 17.0 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex SAPS PF04499.10 ETO36285.1 - 4.3 5.8 14.1 4.7 5.7 9.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ndc1_Nup PF09531.5 ETO36285.1 - 4.8 5.4 9.3 5.2 5.3 6.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2413 PF10310.4 ETO36285.1 - 7.5 5.2 28.1 9 4.9 19.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Peptidase_S30 PF01577.11 ETO36285.1 - 8 5.7 21.2 10 5.4 14.7 1.1 1 0 0 1 1 1 0 Potyvirus P1 protease PUB PF09409.5 ETO36287.1 - 0.0007 19.3 0.3 0.0056 16.4 0.2 2.5 1 1 0 1 1 1 1 PUB domain TPR_12 PF13424.1 ETO36289.1 - 2.5e-110 360.5 19.9 2.8e-17 62.4 0.0 7.9 5 2 2 8 8 8 8 Tetratricopeptide repeat TPR_1 PF00515.23 ETO36289.1 - 1.1e-69 227.3 66.4 2.8e-08 33.0 0.9 13.4 13 0 0 13 13 13 13 Tetratricopeptide repeat TPR_11 PF13414.1 ETO36289.1 - 1.3e-63 210.5 44.2 3.9e-12 45.6 0.5 9.0 6 1 4 10 10 10 8 TPR repeat TPR_7 PF13176.1 ETO36289.1 - 5.5e-58 188.2 19.4 9.8e-06 24.9 0.0 13.5 13 0 0 13 13 13 12 Tetratricopeptide repeat TPR_8 PF13181.1 ETO36289.1 - 1.2e-54 178.0 68.2 1.2e-05 24.7 0.8 13.7 13 0 0 13 13 13 12 Tetratricopeptide repeat TPR_2 PF07719.12 ETO36289.1 - 8.4e-54 175.2 51.1 9.7e-06 25.1 0.5 13.1 13 0 0 13 13 13 11 Tetratricopeptide repeat TPR_10 PF13374.1 ETO36289.1 - 7e-49 162.4 0.0 0.00044 20.0 0.0 13.3 13 0 0 13 13 13 10 Tetratricopeptide repeat TPR_16 PF13432.1 ETO36289.1 - 4.1e-28 97.3 0.0 0.0005 20.6 0.6 8.5 7 2 3 10 10 9 6 Tetratricopeptide repeat TPR_14 PF13428.1 ETO36289.1 - 2.5e-26 89.7 0.0 0.39 11.4 0.0 11.8 10 2 1 11 11 11 5 Tetratricopeptide repeat TPR_6 PF13174.1 ETO36289.1 - 9.7e-17 60.2 24.1 0.011 16.1 0.3 12.0 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO36289.1 - 1.3e-16 59.3 15.2 0.35 11.1 0.0 13.1 12 2 0 13 13 12 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO36289.1 - 1.4e-11 43.3 5.8 0.0061 15.7 0.0 7.8 9 0 0 9 9 9 3 SHNi-TPR TPR_19 PF14559.1 ETO36289.1 - 5e-10 39.5 6.5 0.23 11.8 0.0 7.1 3 1 4 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO36289.1 - 3.6e-09 36.6 36.3 0.00039 20.5 2.0 6.7 2 1 6 8 8 8 6 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 ETO36289.1 - 0.00044 20.0 32.0 0.71 9.8 0.1 9.6 12 0 0 12 12 12 2 MIT (microtubule interacting and transport) domain Kelch_5 PF13854.1 ETO36289.1 - 0.0015 18.4 1.4 0.32 11.0 0.0 3.0 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETO36289.1 - 0.007 16.4 10.1 1 9.6 0.1 4.8 5 0 0 5 5 5 2 Kelch motif DUF1120 PF06551.7 ETO36289.1 - 0.0087 16.3 0.0 0.18 12.1 0.0 3.0 2 1 0 3 3 2 1 Protein of unknown function (DUF1120) Kelch_3 PF13415.1 ETO36289.1 - 0.0088 16.1 0.3 0.11 12.6 0.0 2.9 3 0 0 3 3 2 1 Galactose oxidase, central domain Sel1 PF08238.7 ETO36289.1 - 0.021 15.4 33.3 6 7.6 0.3 10.0 12 0 0 12 12 10 0 Sel1 repeat TPR_5 PF12688.2 ETO36289.1 - 0.29 11.1 0.3 6.6 6.7 0.0 3.2 4 0 0 4 4 3 0 Tetratrico peptide repeat Mob_Pre PF01076.14 ETO36289.1 - 0.46 10.0 13.5 0.089 12.4 0.4 4.3 2 1 2 4 4 4 0 Plasmid recombination enzyme PPR PF01535.15 ETO36289.1 - 1.3 9.2 25.7 6.2 7.0 0.0 8.9 11 0 0 11 11 9 0 PPR repeat WD40 PF00400.27 ETO36290.1 - 7e-156 501.2 50.8 7.6e-13 47.8 0.4 16.1 16 0 0 16 16 16 16 WD domain, G-beta repeat Nup160 PF11715.3 ETO36290.1 - 4e-15 54.9 34.2 0.037 12.1 0.3 12.7 2 2 10 12 12 12 10 Nucleoporin Nup120/160 DUF1258 PF06869.7 ETO36290.1 - 4.1e-06 26.0 8.2 0.17 10.9 0.0 6.6 2 2 4 9 9 9 3 Protein of unknown function (DUF1258) DUF1652 PF07865.6 ETO36290.1 - 0.00015 21.3 1.1 62 3.3 0.0 9.0 11 2 3 14 14 14 0 Protein of unknown function (DUF1652) Mid2 PF04478.7 ETO36290.1 - 0.0061 15.9 26.1 7 6.0 0.1 9.6 3 3 8 12 12 12 3 Mid2 like cell wall stress sensor CppA_C PF14507.1 ETO36290.1 - 0.12 12.5 2.2 4.8 7.4 0.0 4.1 4 0 0 4 4 4 0 CppA C-terminal mRNA_cap_C PF03919.10 ETO36290.1 - 0.16 12.3 6.4 50 4.2 0.1 5.2 4 1 1 6 6 6 0 mRNA capping enzyme, C-terminal domain PD40 PF07676.7 ETO36290.1 - 0.8 9.4 24.0 9.9 5.9 0.1 8.6 11 0 0 11 11 11 0 WD40-like Beta Propeller Repeat CathepsinC_exc PF08773.6 ETO36290.1 - 6.6 6.9 7.9 17 5.5 0.1 5.3 5 2 2 7 7 7 0 Cathepsin C exclusion domain NACHT PF05729.7 ETO36292.1 - 4.9e-09 36.0 0.0 6.4e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETO36292.1 - 2.8e-06 27.6 0.0 2.8e-06 27.6 0.0 1.5 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 ETO36292.1 - 1.1e-05 25.5 0.0 1.7e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 ETO36292.1 - 7.2e-05 22.4 0.1 0.00017 21.2 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 ETO36292.1 - 0.00056 20.7 0.0 0.00087 20.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 ETO36292.1 - 0.002 18.4 0.1 0.0029 17.9 0.1 1.3 1 1 0 1 1 1 1 ABC transporter RNA_helicase PF00910.17 ETO36292.1 - 0.002 18.2 0.3 0.0056 16.8 0.2 1.8 1 1 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 ETO36292.1 - 0.003 16.6 0.2 0.0051 15.9 0.1 1.7 1 1 0 1 1 1 1 Zeta toxin DUF258 PF03193.11 ETO36292.1 - 0.0052 15.9 0.2 0.0083 15.3 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ATP_bind_2 PF03668.10 ETO36292.1 - 0.0056 15.7 0.0 0.0067 15.5 0.0 1.1 1 0 0 1 1 1 1 P-loop ATPase protein family AAA_30 PF13604.1 ETO36292.1 - 0.0093 15.5 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 ETO36292.1 - 0.0096 15.9 3.0 0.025 14.5 2.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETO36292.1 - 0.01 15.7 0.0 0.014 15.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain PRK PF00485.13 ETO36292.1 - 0.011 15.3 0.0 0.013 15.0 0.0 1.4 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA PF00004.24 ETO36292.1 - 0.015 15.5 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 ETO36292.1 - 0.016 14.2 0.3 0.14 11.1 0.0 1.9 1 1 1 2 2 2 0 KAP family P-loop domain AAA_16 PF13191.1 ETO36292.1 - 0.017 15.0 0.1 0.26 11.2 0.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain AAA_5 PF07728.9 ETO36292.1 - 0.026 14.2 0.0 0.051 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 ETO36292.1 - 0.039 13.4 0.1 0.058 12.8 0.0 1.3 1 1 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 ETO36292.1 - 0.062 12.4 0.3 0.36 9.8 0.0 1.9 1 1 1 2 2 2 0 KaiC PduV-EutP PF10662.4 ETO36292.1 - 0.063 12.7 0.0 0.12 11.8 0.0 1.5 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation VirE PF05272.6 ETO36292.1 - 0.064 12.7 0.1 0.1 12.0 0.0 1.5 1 1 0 1 1 1 0 Virulence-associated protein E AAA_29 PF13555.1 ETO36292.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 ETO36292.1 - 0.11 11.8 0.2 5.9 6.2 0.0 2.1 1 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 ETO36292.1 - 0.19 11.6 1.3 0.37 10.6 0.9 1.5 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 ETO36292.1 - 0.2 10.4 1.3 1.3 7.7 0.9 1.9 1 1 0 1 1 1 0 NB-ARC domain G-alpha PF00503.15 ETO36292.1 - 0.23 10.0 4.6 0.33 9.6 2.7 1.6 1 1 0 1 1 1 0 G-protein alpha subunit Myosin_head PF00063.16 ETO36292.1 - 0.42 8.5 5.2 0.15 10.0 0.1 1.9 1 1 1 2 2 2 0 Myosin head (motor domain) WD40 PF00400.27 ETO36293.1 - 5.2e-08 32.4 0.0 1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 WD domain, G-beta repeat DOT1 PF08123.8 ETO36293.1 - 0.06 12.6 0.8 0.087 12.1 0.6 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 RNase_PH PF01138.16 ETO36294.1 - 2.1e-22 79.8 0.2 3.7e-22 79.0 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF2237 PF09996.4 ETO36295.1 - 0.053 13.0 0.2 0.077 12.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2237) Aminotran_1_2 PF00155.16 ETO36296.1 - 2.8e-08 33.0 0.0 3.1e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Ribosomal_S21 PF01165.15 ETO36296.1 - 0.87 9.0 3.7 2.6 7.5 0.2 2.2 2 0 0 2 2 2 0 Ribosomal protein S21 CAP PF00188.21 ETO36297.1 - 0.013 16.0 3.5 0.019 15.4 2.5 1.4 1 1 0 1 1 1 0 Cysteine-rich secretory protein family LURAP PF14854.1 ETO36298.1 - 0.11 12.2 1.4 0.16 11.7 0.7 1.5 1 1 0 1 1 1 0 Leucine rich adaptor protein Rtf2 PF04641.7 ETO36298.1 - 0.69 9.0 17.2 0.96 8.5 11.9 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Band_3_cyto PF07565.8 ETO36298.1 - 1.1 8.6 9.9 1.6 8.2 6.9 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4613 PF15390.1 ETO36298.1 - 2.6 6.0 12.4 3.1 5.8 8.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) PA26 PF04636.8 ETO36298.1 - 2.7 6.5 9.7 2.9 6.4 6.7 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RNA_pol_Rpb1_5 PF04998.12 ETO36298.1 - 6.8 5.8 8.9 7.4 5.7 6.1 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Ras PF00071.17 ETO36299.1 - 2e-56 189.8 0.2 2.6e-56 189.5 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO36299.1 - 1e-20 74.3 0.1 2.6e-20 73.0 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO36299.1 - 3.9e-18 65.3 0.0 5.1e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETO36299.1 - 1.4e-07 30.8 0.1 1.8e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 ETO36299.1 - 7.2e-05 22.2 0.1 0.00097 18.6 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 ETO36299.1 - 9.2e-05 22.3 0.0 0.00013 21.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 ETO36299.1 - 0.0016 18.5 0.0 0.0029 17.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETO36299.1 - 0.0025 17.8 0.1 0.0067 16.4 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 ETO36299.1 - 0.019 14.1 0.1 0.042 13.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 SRPRB PF09439.5 ETO36299.1 - 0.019 14.1 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 ETO36299.1 - 0.031 13.9 0.2 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase AAA_24 PF13479.1 ETO36299.1 - 0.034 13.7 1.7 0.047 13.2 0.4 1.7 2 1 0 2 2 2 0 AAA domain Septin PF00735.13 ETO36299.1 - 0.051 12.5 0.2 0.1 11.6 0.0 1.5 2 0 0 2 2 2 0 Septin NACHT PF05729.7 ETO36299.1 - 0.054 13.1 0.1 0.093 12.3 0.1 1.3 1 0 0 1 1 1 0 NACHT domain DoxA PF07680.6 ETO36299.1 - 0.093 12.3 0.1 0.76 9.3 0.0 2.0 2 0 0 2 2 2 0 TQO small subunit DoxA DAP3 PF10236.4 ETO36299.1 - 0.12 11.2 0.3 1.1 8.1 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Plasmid_parti PF01672.11 ETO36300.1 - 0.58 10.6 0.0 0.58 10.6 0.0 2.4 3 0 0 3 3 3 0 Putative plasmid partition protein Ribos_L4_asso_C PF14374.1 ETO36300.1 - 1 9.2 8.8 5.6 6.9 1.0 2.6 2 0 0 2 2 2 0 60S ribosomal protein L4 C-terminal domain Adaptin_binding PF10199.4 ETO36301.1 - 0.57 10.4 16.6 0.7 10.1 11.5 1.1 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Daxx PF03344.10 ETO36301.1 - 0.84 8.0 19.6 0.87 7.9 13.6 1.0 1 0 0 1 1 1 0 Daxx Family CENP-T PF15511.1 ETO36301.1 - 1.3 8.1 13.4 1.5 7.9 9.3 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CDC45 PF02724.9 ETO36301.1 - 1.7 6.5 13.9 1.8 6.4 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2201_N PF13203.1 ETO36301.1 - 1.9 7.6 13.6 2.1 7.4 9.4 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain Spore_coat_CotO PF14153.1 ETO36301.1 - 1.9 7.8 12.7 2 7.8 8.8 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Nop14 PF04147.7 ETO36301.1 - 2.2 6.1 18.9 2.5 5.9 13.1 1.0 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 ETO36301.1 - 2.5 7.4 20.4 2.9 7.2 14.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Prog_receptor PF02161.10 ETO36301.1 - 2.5 6.8 6.8 3.7 6.2 4.7 1.3 1 0 0 1 1 1 0 Progesterone receptor Peptidase_S64 PF08192.6 ETO36301.1 - 3.7 5.7 6.4 3.8 5.7 4.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 Lin-8 PF03353.10 ETO36301.1 - 3.9 6.6 9.9 4.5 6.4 6.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Neur_chan_memb PF02932.11 ETO36301.1 - 5 6.9 6.1 5.1 6.9 4.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SpoIIIAH PF12685.2 ETO36301.1 - 5.1 6.5 13.4 6.3 6.2 9.3 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Apt1 PF10351.4 ETO36301.1 - 9.4 4.9 9.1 9.9 4.8 6.3 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain TyeA PF09059.5 ETO36302.1 - 0.044 13.7 5.5 0.16 11.9 0.2 3.8 4 0 0 4 4 4 0 TyeA Tox-REase-7 PF15649.1 ETO36302.1 - 0.051 13.6 0.9 0.051 13.6 0.6 3.4 2 1 1 3 3 3 0 Restriction endonuclease fold toxin 7 VPS9 PF02204.13 ETO36302.1 - 2.3 8.2 10.9 0.12 12.3 0.7 3.2 3 1 0 3 3 3 0 Vacuolar sorting protein 9 (VPS9) domain AAA_13 PF13166.1 ETO36304.1 - 0.0013 17.2 29.9 0.0013 17.2 20.8 4.5 2 2 2 4 4 4 1 AAA domain RGS PF00615.14 ETO36305.1 - 4.3e-06 26.8 5.5 9.6e-05 22.4 0.3 3.0 3 0 0 3 3 3 2 Regulator of G protein signaling domain TRAPP PF04051.11 ETO36306.1 - 5.6e-27 94.1 0.2 6.5e-27 93.9 0.2 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DNA_pol3_a_NI PF14480.1 ETO36306.1 - 0.017 14.7 0.2 0.048 13.2 0.1 1.8 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus I Peptidase_C2 PF00648.16 ETO36307.1 - 1.4e-64 217.9 0.2 1.9e-64 217.5 0.1 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease V-SNARE PF05008.10 ETO36308.1 - 0.001 19.1 6.1 0.62 10.2 1.3 2.9 1 1 1 2 2 2 2 Vesicle transport v-SNARE protein N-terminus DUF1829 PF08862.5 ETO36308.1 - 0.011 16.0 2.9 0.81 10.0 0.5 2.8 1 1 2 3 3 3 0 Domain of unknown function DUF1829 TBPIP PF07106.8 ETO36308.1 - 0.019 14.5 7.0 0.032 13.7 4.9 1.5 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2730 PF10805.3 ETO36308.1 - 0.048 13.3 3.9 0.32 10.7 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Spc7 PF08317.6 ETO36308.1 - 0.16 10.6 10.9 0.1 11.2 4.4 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein HR1 PF02185.11 ETO36308.1 - 0.17 11.6 12.4 0.47 10.2 1.2 3.4 2 1 1 3 3 3 0 Hr1 repeat IncA PF04156.9 ETO36308.1 - 0.18 11.3 9.7 0.26 10.8 6.7 1.4 1 1 0 1 1 1 0 IncA protein CENP-F_leu_zip PF10473.4 ETO36308.1 - 0.22 11.3 9.2 5.9 6.7 6.0 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Snapin_Pallidin PF14712.1 ETO36308.1 - 0.37 11.1 8.2 0.97 9.7 4.7 2.1 1 1 1 2 2 2 0 Snapin/Pallidin DSPc PF00782.15 ETO36309.1 - 7.9e-07 28.7 0.2 7.9e-07 28.7 0.2 4.5 5 2 1 6 6 6 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 ETO36309.1 - 0.0005 20.3 0.0 0.0005 20.3 0.0 3.1 3 0 0 3 3 3 1 Tyrosine phosphatase family zf-ribbon_3 PF13248.1 ETO36309.1 - 0.9 8.8 10.8 0.17 11.1 3.6 2.5 2 0 0 2 2 2 0 zinc-ribbon domain SR-25 PF10500.4 ETO36310.1 - 0.0052 16.2 6.5 0.0052 16.2 4.5 1.9 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF4603 PF15376.1 ETO36310.1 - 0.18 8.9 7.9 0.051 10.7 2.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4603) MRL1 PF13003.2 ETO36311.1 - 0.029 14.2 3.4 0.2 11.4 1.1 2.1 2 0 0 2 2 2 0 Ribosomal protein L1 Eapp_C PF10238.4 ETO36311.1 - 1.9 8.3 8.4 4 7.3 5.9 1.5 1 1 0 1 1 1 0 E2F-associated phosphoprotein Stc1 PF12898.2 ETO36313.1 - 0.021 14.8 2.6 0.048 13.7 0.8 2.3 2 0 0 2 2 2 0 Stc1 domain BTB PF00651.26 ETO36313.1 - 0.065 13.2 2.2 0.13 12.2 0.0 2.6 3 0 0 3 3 3 0 BTB/POZ domain DUF3731 PF12531.3 ETO36314.1 - 0.027 14.0 0.5 0.052 13.0 0.4 1.5 1 1 0 1 1 1 0 DNA-K related protein DUF1796 PF08795.5 ETO36315.1 - 0.52 9.9 6.3 1.7 8.2 4.4 1.9 1 1 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) Kelch_6 PF13964.1 ETO36316.1 - 0.00016 21.6 0.1 0.00043 20.3 0.1 1.8 1 0 0 1 1 1 1 Kelch motif Kelch_5 PF13854.1 ETO36316.1 - 0.003 17.4 1.7 0.0034 17.3 0.1 2.0 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.10 ETO36316.1 - 0.033 13.9 0.1 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 Kelch motif Kelch_1 PF01344.20 ETO36316.1 - 0.056 13.0 0.4 0.13 11.8 0.3 1.6 1 0 0 1 1 1 0 Kelch motif Ras PF00071.17 ETO36317.1 - 3.3e-21 75.3 0.3 4.4e-21 74.9 0.2 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO36317.1 - 0.0026 18.2 0.1 0.0068 16.9 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein POT1 PF02765.12 ETO36317.1 - 0.024 14.5 0.2 0.049 13.5 0.1 1.2 1 1 0 1 1 1 0 Telomeric single stranded DNA binding POT1/CDC13 RIX1 PF08167.7 ETO36317.1 - 0.04 13.5 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis GTP_EFTU PF00009.22 ETO36317.1 - 0.059 12.7 0.1 0.082 12.3 0.1 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain NanE PF04131.9 ETO36317.1 - 0.084 11.8 0.1 0.098 11.6 0.0 1.1 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase DUF89 PF01937.14 ETO36317.1 - 0.1 11.3 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF89 DUF900 PF05990.7 ETO36319.1 - 1.8e-08 34.0 0.1 6e-07 29.0 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) RP-C_C PF11800.3 ETO36319.1 - 0.26 10.9 2.7 0.49 10.0 1.9 1.5 1 0 0 1 1 1 0 Replication protein C C-terminal region Zip PF02535.17 ETO36319.1 - 3.2 6.6 5.9 2.1 7.3 1.9 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter Asp_Arg_Hydrox PF05118.10 ETO36320.1 - 9.4e-07 28.8 0.6 2.6e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 Aspartyl/Asparaginyl beta-hydroxylase PhoPQ_related PF10142.4 ETO36321.1 - 7.9e-22 77.2 0.0 9.2e-22 77.0 0.0 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Abhydrolase_5 PF12695.2 ETO36321.1 - 0.043 13.5 0.0 0.1 12.3 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_C15 PF01470.12 ETO36322.1 - 9.1e-20 71.3 0.1 8.1e-15 55.1 0.0 2.1 1 1 1 2 2 2 2 Pyroglutamyl peptidase Mtc PF03820.12 ETO36323.1 - 7.8e-59 198.8 0.7 7.8e-38 129.8 0.0 2.0 2 0 0 2 2 2 2 Tricarboxylate carrier DUF911 PF06023.7 ETO36324.1 - 0.034 13.3 0.1 0.058 12.5 0.1 1.3 1 0 0 1 1 1 0 Archaeal protein of unknown function (DUF911) Kelch_1 PF01344.20 ETO36325.1 - 0.0038 16.7 0.1 1.8 8.1 0.0 2.9 3 0 0 3 3 3 2 Kelch motif Adaptin_binding PF10199.4 ETO36326.1 - 0.0074 16.5 2.2 0.01 16.1 1.5 1.3 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Perilipin PF03036.11 ETO36326.1 - 0.0079 15.0 0.7 0.0098 14.7 0.5 1.2 1 0 0 1 1 1 1 Perilipin family POX PF07526.6 ETO36326.1 - 0.057 13.6 2.7 0.089 13.0 1.9 1.3 1 0 0 1 1 1 0 Associated with HOX IncA PF04156.9 ETO36326.1 - 0.13 11.8 7.6 0.17 11.4 5.3 1.2 1 0 0 1 1 1 0 IncA protein DUF4196 PF13846.1 ETO36326.1 - 0.27 11.5 6.8 0.38 11.0 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4196) DUF740 PF05340.7 ETO36326.1 - 0.38 9.0 3.3 0.44 8.8 2.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF740) GCIP PF13324.1 ETO36326.1 - 0.74 8.9 7.3 1.2 8.3 5.0 1.4 1 1 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF359 PF04019.7 ETO36326.1 - 0.98 8.8 3.3 7.3 6.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF359) S-antigen PF05756.6 ETO36326.1 - 2.9 7.9 10.0 6.3 6.8 6.9 1.5 1 0 0 1 1 1 0 S-antigen protein PPR_3 PF13812.1 ETO36327.1 - 0.0037 17.4 0.2 8 7.0 0.0 4.6 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR PF01535.15 ETO36327.1 - 0.056 13.4 9.9 0.76 9.8 0.1 4.5 5 0 0 5 5 5 0 PPR repeat PH_10 PF15411.1 ETO36327.1 - 0.082 13.1 4.9 0.071 13.3 0.6 2.8 3 0 0 3 3 3 0 Pleckstrin homology domain Ppx-GppA PF02541.11 ETO36329.1 - 0.025 13.7 1.3 0.15 11.2 0.9 2.0 1 1 0 1 1 1 0 Ppx/GppA phosphatase family DUF1845 PF08900.6 ETO36329.1 - 0.089 12.0 0.2 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) TPR_12 PF13424.1 ETO36331.1 - 2.5e-16 59.3 3.5 9e-10 38.3 0.2 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO36331.1 - 1.5e-08 34.1 7.8 5.6e-06 25.9 0.7 2.2 1 1 1 2 2 2 2 TPR repeat TPR_8 PF13181.1 ETO36331.1 - 2.7e-06 26.7 8.0 5.8e-05 22.5 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO36331.1 - 0.00037 20.0 0.8 0.003 17.2 0.0 3.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETO36331.1 - 0.0016 17.9 0.5 0.0016 17.9 0.4 3.9 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETO36331.1 - 0.0027 17.5 0.0 0.0089 15.9 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat BRCA-2_OB3 PF09104.5 ETO36331.1 - 0.0038 17.0 0.2 0.011 15.5 0.2 1.8 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 TPR_2 PF07719.12 ETO36331.1 - 0.007 16.2 5.6 0.014 15.3 0.2 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO36331.1 - 0.012 15.7 0.4 0.13 12.5 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETO36331.1 - 0.016 15.7 0.1 0.2 12.3 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO36331.1 - 0.024 15.1 0.4 0.36 11.3 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETO36332.1 - 2.9e-99 325.1 24.9 7.9e-23 80.2 0.1 5.3 4 1 0 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.23 ETO36332.1 - 2.5e-71 232.5 52.2 3.9e-09 35.7 0.3 10.1 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 ETO36332.1 - 8e-67 220.8 45.5 3.8e-15 55.2 2.9 6.6 3 2 3 7 7 7 7 TPR repeat TPR_10 PF13374.1 ETO36332.1 - 2.7e-66 217.7 0.0 2.3e-07 30.5 0.0 10.4 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_7 PF13176.1 ETO36332.1 - 2.6e-65 211.1 17.6 1.3e-09 37.1 0.0 10.2 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_2 PF07719.12 ETO36332.1 - 8.8e-55 178.2 45.7 3.4e-06 26.5 0.1 10.2 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_8 PF13181.1 ETO36332.1 - 2.3e-52 170.8 53.6 2.1e-06 27.1 2.7 10.4 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_17 PF13431.1 ETO36332.1 - 1.5e-28 96.5 18.1 0.006 16.6 0.0 11.1 11 1 0 11 11 10 8 Tetratricopeptide repeat TPR_14 PF13428.1 ETO36332.1 - 8.3e-27 91.2 0.0 0.16 12.7 0.0 10.1 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.1 ETO36332.1 - 1.2e-25 89.5 5.0 1.3e-05 25.7 0.6 5.9 3 1 4 7 7 7 6 Tetratricopeptide repeat TPR_6 PF13174.1 ETO36332.1 - 3.6e-20 70.9 18.1 0.024 15.0 0.3 10.1 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_3 PF07720.7 ETO36332.1 - 1.1e-15 57.0 43.8 0.00013 21.6 2.0 9.9 10 0 0 10 10 10 5 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO36332.1 - 3.3e-13 48.6 0.5 0.47 9.7 0.0 8.3 9 0 0 9 9 9 3 SHNi-TPR Apc3 PF12895.2 ETO36332.1 - 6.6e-13 48.6 31.4 0.00026 21.0 0.5 6.8 1 1 7 9 9 9 7 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETO36332.1 - 4e-10 39.8 9.8 0.03 14.6 0.2 5.9 2 2 5 7 7 7 3 Tetratricopeptide repeat MIT PF04212.13 ETO36332.1 - 5.6e-09 35.7 33.3 1 9.3 0.0 10.0 8 2 1 10 10 10 4 MIT (microtubule interacting and transport) domain DUF2225 PF09986.4 ETO36332.1 - 2.1e-07 30.6 19.5 0.019 14.3 0.1 4.8 1 1 3 4 4 4 4 Uncharacterized protein conserved in bacteria (DUF2225) TPR_9 PF13371.1 ETO36332.1 - 1.7e-06 27.8 0.1 26 4.7 0.0 6.6 5 4 1 7 7 7 0 Tetratricopeptide repeat PPR PF01535.15 ETO36332.1 - 4.4e-06 26.3 6.6 15 5.8 0.0 7.7 8 0 0 8 8 8 0 PPR repeat DUF627 PF04781.7 ETO36332.1 - 0.00015 21.3 10.0 0.067 12.8 0.1 5.5 4 3 0 4 4 4 2 Protein of unknown function (DUF627) TPR_5 PF12688.2 ETO36332.1 - 0.00065 19.7 4.3 6.6 6.7 0.0 6.2 4 2 2 7 7 7 0 Tetratrico peptide repeat OEP PF02321.13 ETO36332.1 - 0.021 14.4 3.6 0.24 10.9 0.2 3.0 3 1 1 4 4 4 0 Outer membrane efflux protein RPN7 PF10602.4 ETO36332.1 - 0.072 12.4 26.1 7.7 5.8 0.3 8.3 6 4 3 9 9 9 0 26S proteasome subunit RPN7 Sel1 PF08238.7 ETO36332.1 - 3.3 8.4 31.8 23 5.7 1.1 9.1 10 0 0 10 10 9 0 Sel1 repeat Pkinase PF00069.20 ETO36333.1 - 1.3e-11 44.2 0.4 2e-11 43.5 0.2 1.4 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 ETO36333.1 - 2.4e-09 36.5 0.1 6.3e-09 35.1 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 ETO36333.1 - 9.1e-08 31.6 0.1 1.6e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 ETO36333.1 - 2.6e-07 30.6 0.0 7.4e-06 25.8 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 ETO36333.1 - 7.9e-07 28.3 0.2 1.3e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EcKinase PF02958.15 ETO36333.1 - 3.9e-06 26.2 0.0 5.8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 ETO36333.1 - 1.7e-05 24.5 0.6 4.6e-05 23.0 0.4 1.8 1 1 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 ETO36333.1 - 0.021 13.4 0.0 0.048 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Brix PF04427.13 ETO36334.1 - 5.9e-27 94.5 4.4 1.1e-26 93.6 3.0 1.4 1 0 0 1 1 1 1 Brix domain DAGK_acc PF00609.14 ETO36335.1 - 0.072 13.2 1.2 0.1 12.7 0.6 1.4 1 1 0 1 1 1 0 Diacylglycerol kinase accessory domain TPR_12 PF13424.1 ETO36336.1 - 9.3e-93 304.2 46.2 6.5e-21 74.0 2.2 6.4 3 2 4 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.23 ETO36336.1 - 1.6e-49 163.5 55.1 3.3e-08 32.8 1.1 10.6 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_11 PF13414.1 ETO36336.1 - 7.1e-48 160.1 30.0 5.7e-14 51.5 1.0 6.5 5 1 0 6 6 6 5 TPR repeat TPR_2 PF07719.12 ETO36336.1 - 8.4e-44 144.0 40.8 4.3e-06 26.2 0.6 10.4 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_7 PF13176.1 ETO36336.1 - 1.8e-42 139.7 25.0 1.4e-06 27.5 0.1 10.6 9 1 1 10 10 10 8 Tetratricopeptide repeat TPR_8 PF13181.1 ETO36336.1 - 6e-37 122.6 60.8 1.5e-06 27.5 0.6 10.1 10 0 0 10 10 9 8 Tetratricopeptide repeat TPR_10 PF13374.1 ETO36336.1 - 8.1e-36 120.9 0.7 5.1e-08 32.5 0.0 9.4 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.1 ETO36336.1 - 1.2e-19 70.4 1.3 7e-05 23.3 0.3 7.1 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETO36336.1 - 1.6e-12 46.8 0.0 2.5 8.9 0.0 7.7 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO36336.1 - 4.4e-10 39.3 20.0 0.3 11.6 0.3 9.1 9 0 0 9 9 9 2 Tetratricopeptide repeat Peptidase_C14 PF00656.17 ETO36336.1 - 5.6e-10 39.3 0.2 1.4e-09 37.9 0.1 1.7 1 0 0 1 1 1 1 Caspase domain TPR_19 PF14559.1 ETO36336.1 - 1.6e-09 37.9 5.0 0.15 12.4 0.0 5.8 4 2 1 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO36336.1 - 9e-08 31.7 26.6 1.2 9.4 0.0 10.1 11 1 0 11 11 9 2 Tetratricopeptide repeat MIT PF04212.13 ETO36336.1 - 0.0015 18.3 27.3 3.4 7.6 0.2 7.9 6 1 0 7 7 7 1 MIT (microtubule interacting and transport) domain OEP PF02321.13 ETO36336.1 - 0.0017 18.0 5.8 0.55 9.7 0.2 3.3 2 1 1 3 3 3 2 Outer membrane efflux protein TPR_3 PF07720.7 ETO36336.1 - 0.002 17.9 27.6 0.26 11.1 0.5 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat Phage_Treg PF04761.7 ETO36336.1 - 0.16 11.7 6.2 0.25 11.1 0.1 3.8 3 0 0 3 3 3 0 Lactococcus bacteriophage putative transcription regulator PPR PF01535.15 ETO36336.1 - 0.8 9.8 20.4 2.9 8.0 0.0 7.7 8 0 0 8 8 8 0 PPR repeat SHNi-TPR PF10516.4 ETO36336.1 - 4.6 6.5 8.6 6.4 6.1 0.0 5.4 8 0 0 8 8 8 0 SHNi-TPR INCENP_N PF12178.3 ETO36337.1 - 0.031 13.8 0.3 0.12 11.9 0.1 2.1 2 0 0 2 2 2 0 Chromosome passenger complex (CPC) protein INCENP N terminal Neur_chan_memb PF02932.11 ETO36337.1 - 0.12 12.2 0.1 0.12 12.2 0.0 2.4 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region GCD14 PF08704.5 ETO36337.1 - 0.16 11.4 3.7 0.14 11.6 0.1 2.2 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit PBP1_TM PF14812.1 ETO36337.1 - 0.45 10.8 3.9 6.1 7.2 0.1 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF912 PF06024.7 ETO36337.1 - 8.2 6.5 17.7 2.9 8.0 0.4 3.9 2 2 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) WD40 PF00400.27 ETO36338.1 - 8.6e-44 145.9 22.0 5.8e-10 38.6 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO36338.1 - 8.8e-12 43.9 1.8 0.0036 15.5 0.1 4.1 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO36338.1 - 0.018 15.2 4.7 12 6.2 0.4 4.0 3 1 0 3 3 3 0 Kelch motif DUF3601 PF12208.3 ETO36338.1 - 0.02 14.8 0.0 0.64 9.9 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3601) Zwint PF15556.1 ETO36338.1 - 0.029 13.6 6.4 0.046 12.9 4.4 1.3 1 0 0 1 1 1 0 ZW10 interactor PQQ_2 PF13360.1 ETO36338.1 - 0.04 13.3 0.1 0.93 8.9 0.0 2.2 2 0 0 2 2 2 0 PQQ-like domain HARP PF07443.8 ETO36338.1 - 0.043 13.1 1.0 1.2 8.5 0.0 3.0 3 0 0 3 3 3 0 HepA-related protein (HARP) BBS2_Mid PF14783.1 ETO36338.1 - 0.05 13.3 1.3 4 7.2 0.1 3.3 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region FBA PF04300.8 ETO36338.1 - 0.11 12.4 1.3 0.19 11.6 0.9 1.3 1 0 0 1 1 1 0 F-box associated region DUF3150 PF11348.3 ETO36338.1 - 0.14 11.2 3.9 0.24 10.4 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) AbiH PF14253.1 ETO36338.1 - 2.1 7.8 14.9 2.5 7.6 10.2 1.4 1 1 0 1 1 1 0 Bacteriophage abortive infection AbiH V-ATPase_G PF03179.10 ETO36338.1 - 4.2 7.7 12.1 12 6.2 8.4 1.8 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit OmpH PF03938.9 ETO36338.1 - 6.6 6.6 15.1 9.6 6.1 10.5 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AAA PF00004.24 ETO36339.1 - 3.5e-10 40.2 0.0 0.00026 21.1 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETO36339.1 - 9.5e-09 35.0 0.1 6.5e-05 22.6 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETO36339.1 - 1.3e-06 28.5 0.0 0.04 14.0 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 ETO36339.1 - 3.5e-05 23.6 0.0 0.0077 16.1 0.0 3.3 3 0 0 3 3 2 1 AAA domain ABC_tran PF00005.22 ETO36339.1 - 4.9e-05 23.6 0.0 0.00088 19.5 0.0 2.6 2 0 0 2 2 2 1 ABC transporter Viral_helicase1 PF01443.13 ETO36339.1 - 6e-05 22.6 0.4 0.0037 16.8 0.0 2.7 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 ETO36339.1 - 6.5e-05 23.0 0.1 0.018 15.0 0.0 3.5 3 1 1 4 4 4 1 AAA ATPase domain DUF258 PF03193.11 ETO36339.1 - 0.00024 20.3 0.0 0.00079 18.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 ETO36339.1 - 0.00027 20.6 1.4 0.034 13.8 0.0 3.7 3 1 0 3 3 3 1 Archaeal ATPase AAA_2 PF07724.9 ETO36339.1 - 0.0016 18.3 0.0 0.034 14.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) PduV-EutP PF10662.4 ETO36339.1 - 0.0018 17.8 0.0 0.014 14.9 0.0 2.4 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Sigma54_activ_2 PF14532.1 ETO36339.1 - 0.0029 17.6 0.0 0.19 11.7 0.0 3.2 2 2 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 ETO36339.1 - 0.0045 16.4 0.1 1.3 8.3 0.0 3.6 3 1 1 4 4 4 1 IstB-like ATP binding protein MCM PF00493.18 ETO36339.1 - 0.0053 15.5 0.7 0.27 10.0 0.0 3.0 3 0 0 3 3 3 1 MCM2/3/5 family DUF815 PF05673.8 ETO36339.1 - 0.0062 15.4 0.0 0.034 13.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 ETO36339.1 - 0.022 13.9 0.6 4.8 6.2 0.0 3.6 3 1 0 3 3 3 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 ETO36339.1 - 0.031 13.7 0.1 1.6 8.1 0.0 3.0 4 0 0 4 4 2 0 Sigma-54 interaction domain NACHT PF05729.7 ETO36339.1 - 0.049 13.2 1.0 0.57 9.8 0.0 3.1 3 1 0 3 3 3 0 NACHT domain T2SE PF00437.15 ETO36339.1 - 0.064 12.1 0.0 1 8.2 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Miro PF08477.8 ETO36339.1 - 0.065 13.7 0.0 0.26 11.8 0.0 2.1 1 0 0 1 1 1 0 Miro-like protein UPF0079 PF02367.12 ETO36339.1 - 0.073 12.7 0.0 0.29 10.7 0.0 2.0 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 ETO36339.1 - 0.086 13.6 0.8 0.43 11.4 0.2 2.5 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.1 ETO36339.1 - 0.13 12.2 0.2 1.2 9.1 0.2 2.6 2 1 0 2 2 1 0 AAA domain AAA_18 PF13238.1 ETO36339.1 - 0.13 12.6 3.7 0.15 12.3 0.0 3.1 3 1 0 3 3 3 0 AAA domain AAA_23 PF13476.1 ETO36339.1 - 0.46 10.7 0.0 0.46 10.7 0.0 3.6 3 1 0 3 3 3 0 AAA domain zf-TRAF PF02176.13 ETO36341.1 - 1.2e-06 28.7 2.6 1.2e-06 28.7 1.8 2.6 2 1 1 3 3 3 1 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 ETO36341.1 - 1.6 8.8 8.8 0.25 11.3 0.9 3.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FAM195 PF14799.1 ETO36342.1 - 0.026 14.3 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 FAM195 family FANCI_S1-cap PF14674.1 ETO36343.1 - 0.086 12.9 0.3 0.32 11.0 0.0 2.1 2 0 0 2 2 2 0 FANCI solenoid 1 cap Mvb12 PF09452.5 ETO36343.1 - 2.6 8.2 4.8 13 6.0 0.0 3.6 4 1 0 4 4 4 0 ESCRT-I subunit Mvb12 PT PF04886.7 ETO36347.1 - 4.1e-19 67.5 144.3 0.018 14.3 17.4 7.7 1 1 2 3 3 3 2 PT repeat TSP_1 PF00090.14 ETO36347.1 - 2.3e-05 24.4 10.4 6.5e-05 22.9 7.2 1.9 1 0 0 1 1 1 1 Thrombospondin type 1 domain CDC45 PF02724.9 ETO36347.1 - 1.7 6.5 14.0 2.6 5.9 9.7 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 ETO36347.1 - 6.9 5.9 12.8 12 5.2 8.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Popeye PF04831.8 ETO36348.1 - 1.3e-13 50.9 0.0 1.6e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.24 ETO36348.1 - 0.019 14.7 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain YlzJ PF14035.1 ETO36348.1 - 0.035 14.1 0.1 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 YlzJ-like protein Sec62 PF03839.11 ETO36348.1 - 0.22 10.8 2.7 0.28 10.5 1.9 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Radial_spoke PF04712.7 ETO36348.1 - 0.3 9.7 7.2 0.35 9.5 5.0 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Trypan_glycop_C PF10659.4 ETO36348.1 - 0.34 11.2 4.9 0.49 10.7 3.4 1.2 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain SDA1 PF05285.7 ETO36348.1 - 0.57 9.4 14.0 0.7 9.1 9.7 1.0 1 0 0 1 1 1 0 SDA1 DUF4637 PF15470.1 ETO36348.1 - 1.3 8.6 6.6 1.7 8.2 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) TRAP_alpha PF03896.11 ETO36348.1 - 9.3 5.1 9.0 12 4.8 6.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit WD40 PF00400.27 ETO36350.1 - 9.5e-174 557.9 70.1 1.1e-13 50.4 0.6 14.4 14 0 0 14 14 14 14 WD domain, G-beta repeat Gmad1 PF10647.4 ETO36350.1 - 1.1e-06 28.2 0.3 0.032 13.6 0.0 4.9 4 2 0 4 4 4 1 Lipoprotein LpqB beta-propeller domain NACHT PF05729.7 ETO36350.1 - 3.3e-05 23.6 0.0 7.3e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.7 ETO36350.1 - 0.001 18.6 26.4 13 5.6 0.1 10.5 12 0 0 12 12 12 1 WD40-like Beta Propeller Repeat AAA_22 PF13401.1 ETO36350.1 - 0.0013 18.8 0.0 0.0047 17.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETO36350.1 - 0.0026 18.0 0.1 0.0026 18.0 0.1 3.6 3 2 2 5 5 5 1 AAA domain AAA_17 PF13207.1 ETO36350.1 - 0.0067 17.2 0.0 0.035 14.9 0.0 2.4 1 0 0 1 1 1 1 AAA domain zf-NADH-PPase PF09297.6 ETO36350.1 - 0.17 11.3 0.2 7 6.2 0.0 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Ras PF00071.17 ETO36351.1 - 2e-19 69.5 2.6 4e-11 42.5 0.3 2.8 3 0 0 3 3 3 2 Ras family Miro PF08477.8 ETO36351.1 - 5.2e-08 33.3 0.1 4.6e-06 27.1 0.0 3.3 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO36351.1 - 4.4e-06 26.0 0.7 0.00074 18.8 0.0 2.9 3 0 0 3 3 3 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO36351.1 - 0.051 13.0 0.2 0.051 13.0 0.1 2.3 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 ETO36351.1 - 0.056 13.5 0.0 0.19 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain Bud13 PF09736.4 ETO36353.1 - 1.5 9.0 20.0 10 6.3 13.9 2.2 1 1 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex FTA4 PF13093.1 ETO36354.1 - 0.036 13.4 0.1 0.046 13.1 0.1 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 WD40 PF00400.27 ETO36354.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 WD domain, G-beta repeat CorA PF01544.13 ETO36355.1 - 5.4e-34 117.5 0.7 1.2e-33 116.3 0.5 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein RNA_pol_Rpb2_6 PF00562.23 ETO36356.1 - 2.6e-29 102.1 0.1 3e-29 101.9 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.15 ETO36356.1 - 1.9e-12 47.2 0.1 4.6e-12 46.0 0.1 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 tRNA_NucTransf2 PF09249.6 ETO36356.1 - 0.084 12.7 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 tRNA nucleotidyltransferase, second domain Nudix_N_2 PF14803.1 ETO36356.1 - 0.14 11.8 0.2 0.14 11.8 0.1 1.7 2 0 0 2 2 2 0 Nudix N-terminal RNA_pol_Rpb2_6 PF00562.23 ETO36357.1 - 3.4e-64 217.0 0.0 3.4e-64 217.0 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 FAM176 PF14851.1 ETO36357.1 - 0.0004 20.1 3.0 0.00067 19.3 2.1 1.4 1 0 0 1 1 1 1 FAM176 family OAD_gamma PF04277.8 ETO36357.1 - 0.0035 17.6 1.1 0.0076 16.6 0.7 1.6 1 0 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain DUF1510 PF07423.6 ETO36357.1 - 0.0037 16.6 5.8 0.0058 16.0 4.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Mem_trans PF03547.13 ETO36357.1 - 0.0062 14.8 0.5 0.0056 15.0 0.4 1.1 1 0 0 1 1 1 1 Membrane transport protein TMEM51 PF15345.1 ETO36357.1 - 0.0065 16.1 6.2 0.0095 15.6 4.3 1.3 1 0 0 1 1 1 1 Transmembrane protein 51 IncA PF04156.9 ETO36357.1 - 0.0076 15.8 3.2 0.01 15.4 2.2 1.2 1 0 0 1 1 1 1 IncA protein Nucleoside_tran PF01733.13 ETO36357.1 - 0.01 15.0 1.3 0.017 14.2 0.9 1.4 1 0 0 1 1 1 0 Nucleoside transporter Ctr PF04145.10 ETO36357.1 - 0.013 15.5 0.5 0.02 14.9 0.3 1.4 1 0 0 1 1 1 0 Ctr copper transporter family DUF2615 PF11027.3 ETO36357.1 - 0.02 14.8 0.8 0.049 13.5 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) IgaA PF07095.6 ETO36357.1 - 0.022 12.5 0.6 0.027 12.2 0.4 1.1 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA TMEM154 PF15102.1 ETO36357.1 - 0.025 14.3 6.1 0.061 13.0 4.2 1.8 1 1 0 1 1 1 0 TMEM154 protein family Protocadherin PF08374.6 ETO36357.1 - 0.036 13.7 3.4 0.054 13.1 2.3 1.3 1 0 0 1 1 1 0 Protocadherin EspG PF06872.6 ETO36357.1 - 0.038 12.3 0.0 0.056 11.7 0.0 1.2 1 0 0 1 1 1 0 EspG protein DUF4366 PF14283.1 ETO36357.1 - 0.039 13.3 1.9 0.065 12.6 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Pox_Ag35 PF03286.9 ETO36357.1 - 0.055 12.9 10.5 0.089 12.3 7.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4303 PF14136.1 ETO36357.1 - 0.078 12.6 2.9 0.085 12.4 1.1 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4303) BTV_NS2 PF04514.7 ETO36357.1 - 0.099 11.5 8.2 0.15 10.9 5.7 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FHIPEP PF00771.15 ETO36357.1 - 0.12 10.6 3.0 0.15 10.3 2.1 1.1 1 0 0 1 1 1 0 FHIPEP family Anoctamin PF04547.7 ETO36357.1 - 0.15 10.7 4.4 0.23 10.0 3.0 1.3 1 0 0 1 1 1 0 Calcium-activated chloride channel DDRGK PF09756.4 ETO36357.1 - 0.15 11.4 17.4 0.27 10.6 12.1 1.3 1 0 0 1 1 1 0 DDRGK domain SID-1_RNA_chan PF13965.1 ETO36357.1 - 0.18 9.9 3.6 0.25 9.4 2.5 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PBP1_TM PF14812.1 ETO36357.1 - 0.23 11.8 13.3 0.5 10.7 9.2 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal OSTbeta PF15048.1 ETO36357.1 - 0.24 11.4 4.8 0.51 10.4 3.3 1.6 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Sporozoite_P67 PF05642.6 ETO36357.1 - 0.25 9.1 1.4 0.36 8.6 0.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4446 PF14584.1 ETO36357.1 - 0.26 11.1 8.4 0.49 10.2 5.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Neur_chan_memb PF02932.11 ETO36357.1 - 0.28 11.0 1.7 0.34 10.7 1.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S49_N PF08496.5 ETO36357.1 - 0.42 10.4 10.0 0.81 9.4 6.9 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal K_trans PF02705.11 ETO36357.1 - 0.6 8.4 2.4 0.91 7.7 1.7 1.3 1 0 0 1 1 1 0 K+ potassium transporter Folate_carrier PF01770.13 ETO36357.1 - 0.97 7.8 3.5 1.4 7.3 2.4 1.2 1 0 0 1 1 1 0 Reduced folate carrier ORC3_N PF07034.6 ETO36357.1 - 1.6 7.6 7.1 2.4 7.0 4.9 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus DUF2208 PF09973.4 ETO36357.1 - 1.6 7.9 13.5 0.66 9.1 5.7 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) DUF2215 PF10225.4 ETO36357.1 - 1.7 8.0 4.1 2.7 7.3 2.8 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Conotoxin PF02950.12 ETO36357.1 - 2.1 9.2 4.9 7.6 7.4 3.4 2.1 1 1 0 1 1 1 0 Conotoxin Endonuc_Holl PF10107.4 ETO36357.1 - 2.4 7.8 11.3 4.4 6.9 7.9 1.4 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Bap31 PF05529.7 ETO36357.1 - 3.5 7.0 14.4 4.5 6.6 9.3 1.7 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like EphA2_TM PF14575.1 ETO36357.1 - 4.1 7.8 9.4 4.2 7.8 4.7 2.5 2 1 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain Vpu PF00558.14 ETO36357.1 - 5.1 6.7 6.6 13 5.4 4.6 1.8 1 1 0 1 1 1 0 Vpu protein Sec62 PF03839.11 ETO36357.1 - 9.9 5.4 10.5 20 4.5 7.3 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 RNA_pol_Rpa2_4 PF06883.7 ETO36358.1 - 0.017 15.0 0.0 0.32 10.9 0.0 2.7 3 0 0 3 3 3 0 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_3 PF04565.11 ETO36358.1 - 0.023 14.4 0.0 0.059 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 3 LicD PF04991.8 ETO36358.1 - 0.061 13.4 1.6 0.29 11.2 0.3 2.2 2 0 0 2 2 2 0 LicD family WD40 PF00400.27 ETO36359.1 - 1.7e-40 135.4 2.1 2e-12 46.4 0.2 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat eIF2A PF08662.6 ETO36359.1 - 6.2e-08 32.5 0.2 0.00044 20.0 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO36359.1 - 5.2e-06 25.9 3.6 1.6 8.4 0.1 4.4 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO36359.1 - 1.9e-05 24.2 0.8 0.0078 15.7 0.1 2.1 1 1 1 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 ETO36359.1 - 7.5e-05 21.6 1.7 0.14 10.9 0.1 3.1 1 1 1 2 2 2 2 Nup133 N terminal like Proteasome_A_N PF10584.4 ETO36359.1 - 0.0019 17.4 3.4 0.069 12.4 0.0 3.7 4 0 0 4 4 4 1 Proteasome subunit A N-terminal signature Apc4_WD40 PF12894.2 ETO36359.1 - 0.016 14.7 0.0 0.63 9.5 0.0 3.2 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Str_synth PF03088.11 ETO36359.1 - 0.019 15.0 0.0 2.6 8.1 0.0 2.5 2 1 0 2 2 2 0 Strictosidine synthase Cytochrom_D1 PF02239.11 ETO36359.1 - 0.019 13.2 0.1 0.054 11.7 0.1 1.8 1 1 2 3 3 3 0 Cytochrome D1 heme domain Nup160 PF11715.3 ETO36359.1 - 0.041 12.0 0.4 0.33 9.0 0.0 2.2 1 1 0 2 2 2 0 Nucleoporin Nup120/160 MaoC_dehydratas PF01575.14 ETO36360.1 - 1.8e-12 46.7 0.0 4e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain CBFD_NFYB_HMF PF00808.18 ETO36361.1 - 1.5e-10 40.9 6.9 5.7e-08 32.6 0.1 2.8 3 0 0 3 3 3 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 ETO36361.1 - 0.016 15.3 0.5 0.3 11.2 0.2 2.3 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 FancD2 PF14631.1 ETO36361.1 - 0.33 7.9 8.6 0.37 7.8 6.0 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Daxx PF03344.10 ETO36361.1 - 0.4 9.0 20.1 0.49 8.8 13.9 1.1 1 0 0 1 1 1 0 Daxx Family DUF2422 PF10337.4 ETO36361.1 - 0.63 8.7 5.9 0.74 8.5 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Hid1 PF12722.2 ETO36361.1 - 3.4 5.2 12.6 3.9 5.0 8.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein HisKA_3 PF07730.8 ETO36362.1 - 0.31 11.4 5.6 0.19 12.1 0.3 3.1 3 0 0 3 3 3 0 Histidine kinase SID-1_RNA_chan PF13965.1 ETO36362.1 - 0.73 7.9 11.2 0.23 9.5 4.8 2.1 1 1 1 2 2 2 0 dsRNA-gated channel SID-1 GerA PF03323.8 ETO36364.1 - 0.22 9.6 3.7 0.24 9.5 2.5 1.2 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein START PF01852.14 ETO36365.1 - 3.4e-13 49.4 0.0 5.4e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 START domain WD40 PF00400.27 ETO36366.1 - 2.7e-49 163.3 23.8 3.4e-10 39.3 0.8 7.6 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO36366.1 - 9.1e-07 27.3 15.2 0.25 9.4 0.0 6.4 2 1 3 7 7 7 5 Nucleoporin Nup120/160 Vasohibin PF14822.1 ETO36366.1 - 0.0097 15.0 1.0 0.016 14.3 0.7 1.3 1 0 0 1 1 1 1 Vasohibin Rabaptin PF03528.10 ETO36366.1 - 1.5 8.7 10.2 3.1 7.7 7.1 1.5 1 0 0 1 1 1 0 Rabaptin PUB PF09409.5 ETO36367.1 - 0.00092 18.9 0.4 0.0081 15.9 0.2 2.1 1 1 0 1 1 1 1 PUB domain DUF2149 PF09919.4 ETO36369.1 - 0.099 12.7 0.1 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) WD40 PF00400.27 ETO36370.1 - 4.5e-30 102.4 6.2 2.8e-11 42.8 0.1 4.6 4 1 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO36370.1 - 0.00034 18.9 0.4 0.46 8.5 0.1 2.4 1 1 2 3 3 3 2 Nucleoporin Nup120/160 WD40 PF00400.27 ETO36371.1 - 1.4e-24 84.9 11.6 8.2e-09 35.0 0.1 4.1 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO36371.1 - 3.2e-05 22.2 1.6 0.39 8.7 0.0 2.9 1 1 2 3 3 3 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO36371.1 - 0.0064 16.2 1.2 0.018 14.8 0.1 2.0 1 1 1 2 2 2 1 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.6 ETO36371.1 - 0.051 13.2 3.3 0.71 9.5 1.4 2.7 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A PUB PF09409.5 ETO36372.1 - 0.0018 18.0 1.2 0.0033 17.1 0.3 1.9 2 0 0 2 2 2 1 PUB domain Syntaxin PF00804.20 ETO36372.1 - 0.02 15.0 2.7 0.027 14.6 0.7 1.8 2 0 0 2 2 2 0 Syntaxin CUE PF02845.11 ETO36372.1 - 0.095 12.2 0.5 0.19 11.2 0.1 1.8 2 0 0 2 2 2 0 CUE domain Rsa3 PF14615.1 ETO36372.1 - 0.11 11.7 0.1 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 Ribosome-assembly protein 3 PCI PF01399.22 ETO36372.1 - 0.11 12.8 3.8 0.095 13.0 0.5 2.2 1 1 1 2 2 2 0 PCI domain DUF4296 PF14129.1 ETO36372.1 - 0.18 11.9 2.9 1.9 8.6 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4296) DUF2666 PF10869.3 ETO36372.1 - 0.21 11.5 3.2 3.7 7.6 2.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2666) Fcf1 PF04900.7 ETO36373.1 - 0.031 14.3 0.6 1.6 8.8 0.0 2.1 2 0 0 2 2 2 0 Fcf1 Resolvase PF00239.16 ETO36373.1 - 0.079 12.8 0.4 11 5.9 0.0 2.1 1 1 1 2 2 2 0 Resolvase, N terminal domain Sigma_reg_C PF13791.1 ETO36373.1 - 0.92 9.5 8.6 1.2 9.1 6.0 1.2 1 1 0 1 1 1 0 Sigma factor regulator C-terminal WD40 PF00400.27 ETO36374.1 - 5.1e-05 22.9 0.4 0.00026 20.7 0.4 1.9 2 0 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO36374.1 - 0.11 10.6 0.0 0.11 10.6 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 AP_endonuc_2 PF01261.19 ETO36375.1 - 0.11 11.7 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel WD40 PF00400.27 ETO36377.1 - 3.5e-39 131.2 4.2 6.3e-14 51.2 0.0 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO36377.1 - 2.4e-07 29.2 1.0 0.0053 14.9 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO36377.1 - 0.00057 18.7 2.0 0.37 9.4 0.1 3.0 1 1 1 2 2 2 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETO36377.1 - 0.00092 17.6 0.4 0.03 12.6 0.0 2.0 1 1 1 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.6 ETO36377.1 - 0.0012 18.6 0.0 0.0035 17.0 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 ETO36377.1 - 0.0052 16.2 0.0 0.052 12.9 0.0 2.0 2 0 0 2 2 2 1 PQQ-like domain PD40 PF07676.7 ETO36377.1 - 0.06 13.0 2.0 7.4 6.3 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat SusE PF14292.1 ETO36377.1 - 0.067 13.0 0.0 5.4 6.8 0.0 2.6 2 1 0 2 2 2 0 SusE outer membrane protein Nbas_N PF15492.1 ETO36377.1 - 0.071 12.1 0.1 0.55 9.2 0.1 2.1 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Sod_Fe_C PF02777.13 ETO36379.1 - 7.8e-08 32.1 0.1 0.0018 18.0 0.0 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 ETO36379.1 - 0.096 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Amino_oxidase PF01593.19 ETO36380.1 - 1.3e-14 54.1 0.0 0.00028 20.0 0.0 3.6 3 1 0 3 3 3 3 Flavin containing amine oxidoreductase Ank_2 PF12796.2 ETO36380.1 - 5.3e-07 29.8 0.4 1.6e-05 25.1 0.0 2.9 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO36380.1 - 0.00013 21.5 0.4 0.016 14.9 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeat Pyr_redox_2 PF07992.9 ETO36380.1 - 0.00016 21.6 0.0 0.00032 20.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETO36380.1 - 0.00036 20.4 1.3 0.02 14.8 0.9 2.6 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ETO36380.1 - 0.00094 18.1 0.0 0.0015 17.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 ETO36380.1 - 0.0016 17.5 0.1 0.0037 16.4 0.0 1.5 2 0 0 2 2 2 1 Thi4 family Ank_4 PF13637.1 ETO36380.1 - 0.0042 17.5 0.0 1.4 9.4 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DAO PF01266.19 ETO36380.1 - 0.0046 15.9 0.3 0.0071 15.2 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 ETO36380.1 - 0.0064 15.0 0.2 0.011 14.2 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 ETO36380.1 - 0.018 14.1 0.1 0.03 13.3 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Ank_3 PF13606.1 ETO36380.1 - 0.019 15.1 0.5 2.4 8.6 0.1 3.4 2 0 0 2 2 2 0 Ankyrin repeat GIDA PF01134.17 ETO36380.1 - 0.021 13.7 1.5 0.033 13.0 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Ank_5 PF13857.1 ETO36380.1 - 0.06 13.6 1.8 0.41 10.9 0.1 3.1 3 1 1 4 4 2 0 Ankyrin repeats (many copies) Lycopene_cycl PF05834.7 ETO36380.1 - 0.073 11.9 0.1 0.12 11.2 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Malic_M PF03949.10 ETO36380.1 - 0.092 12.2 0.2 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain FBP PF07299.6 ETO36382.1 - 0.078 12.3 0.8 0.086 12.1 0.5 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein (FBP) DUF3342 PF11822.3 ETO36383.1 - 0.00063 18.9 2.4 0.00063 18.9 1.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) HTH_Tnp_1_2 PF13022.1 ETO36383.1 - 0.032 14.0 0.3 0.044 13.5 0.2 1.3 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase zf-P11 PF03854.9 ETO36383.1 - 0.068 12.6 1.1 0.16 11.4 0.7 1.6 1 0 0 1 1 1 0 P-11 zinc finger DUF2357 PF09823.4 ETO36384.1 - 0.039 13.0 0.7 0.047 12.7 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) Ank_2 PF12796.2 ETO36385.1 - 1.4e-08 34.9 1.5 1.1e-07 32.1 0.1 2.6 2 2 1 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETO36385.1 - 2.2e-06 27.2 0.4 6e-05 22.6 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 ETO36385.1 - 1.1e-05 25.7 0.8 4.4e-05 23.8 0.2 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETO36385.1 - 0.00026 20.9 0.7 0.13 12.5 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 ETO36385.1 - 0.014 15.6 0.2 0.047 13.9 0.1 1.9 1 1 0 1 1 1 0 Ankyrin repeats (many copies) SPRY PF00622.23 ETO36386.1 - 5.1e-09 36.2 0.1 1e-08 35.3 0.1 1.5 1 0 0 1 1 1 1 SPRY domain DUF566 PF04484.7 ETO36386.1 - 6.6 6.1 13.2 9.3 5.6 9.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Paf1 PF03985.8 ETO36388.1 - 0.0062 15.3 9.4 0.0068 15.1 6.5 1.1 1 0 0 1 1 1 1 Paf1 tRNA_NucTransf2 PF09249.6 ETO36388.1 - 0.028 14.2 0.7 0.045 13.6 0.2 1.5 1 1 1 2 2 2 0 tRNA nucleotidyltransferase, second domain Archease PF01951.11 ETO36388.1 - 0.047 13.6 0.2 0.086 12.7 0.1 1.4 1 0 0 1 1 1 0 Archease protein family (MTH1598/TM1083) DUF2457 PF10446.4 ETO36388.1 - 0.1 11.3 9.2 0.12 11.1 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TRAP_alpha PF03896.11 ETO36388.1 - 0.57 9.1 6.1 0.7 8.8 4.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Daxx PF03344.10 ETO36388.1 - 0.8 8.1 11.7 0.98 7.8 8.1 1.1 1 0 0 1 1 1 0 Daxx Family PBP1_TM PF14812.1 ETO36388.1 - 5.4 7.4 9.6 8.5 6.7 6.6 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WD40 PF00400.27 ETO36389.1 - 0.0013 18.5 3.3 0.08 12.8 0.0 4.1 4 1 0 4 4 4 1 WD domain, G-beta repeat DUF1900 PF08954.6 ETO36389.1 - 0.062 12.8 0.0 6.3 6.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1900) SR-25 PF10500.4 ETO36389.1 - 0.47 9.8 9.2 0.79 9.1 6.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CAP_N PF01213.14 ETO36391.1 - 0.0017 17.7 4.4 0.003 16.8 3.0 1.5 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal TraG-D_C PF12696.2 ETO36391.1 - 0.089 12.6 2.2 0.47 10.3 0.1 2.9 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG Mito_fiss_reg PF05308.6 ETO36391.1 - 0.1 11.9 10.7 0.038 13.3 5.5 1.7 2 0 0 2 2 2 0 Mitochondrial fission regulator 4HBT_3 PF13622.1 ETO36391.1 - 0.12 12.0 1.9 0.18 11.4 1.3 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily WD40 PF00400.27 ETO36397.1 - 6.2e-19 67.1 3.9 8.4e-07 28.6 0.3 3.7 3 1 1 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO36397.1 - 2e-05 22.9 0.1 0.075 11.1 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO36397.1 - 0.0005 18.9 1.2 0.044 12.5 0.1 2.0 1 1 1 2 2 2 2 Nup133 N terminal like RhgB_N PF09284.5 ETO36397.1 - 0.04 13.2 0.0 0.049 12.9 0.0 1.1 1 0 0 1 1 1 0 Rhamnogalacturonase B, N-terminal Vpu PF00558.14 ETO36398.1 - 0.026 14.0 2.0 4.8 6.8 0.1 2.9 3 0 0 3 3 3 0 Vpu protein LRR_8 PF13855.1 ETO36400.1 - 2.1e-13 49.7 16.7 7.4e-06 25.6 2.7 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 ETO36400.1 - 3.4e-13 48.8 26.8 0.00048 19.6 1.5 4.8 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETO36400.1 - 4.6e-13 47.2 19.2 0.067 13.2 0.3 6.8 7 0 0 7 7 7 5 Leucine Rich Repeat LRR_7 PF13504.1 ETO36400.1 - 0.0019 18.0 13.0 34 5.2 0.0 5.9 6 0 0 6 6 6 0 Leucine rich repeat LRR_6 PF13516.1 ETO36400.1 - 0.0033 17.3 16.2 17 5.8 0.2 6.1 5 1 1 6 6 6 1 Leucine Rich repeat Snapin_Pallidin PF14712.1 ETO36400.1 - 0.033 14.4 0.3 8 6.8 0.1 2.8 2 1 1 3 3 3 0 Snapin/Pallidin DUF1299 PF06975.6 ETO36400.1 - 4.7 7.1 7.0 4.3 7.2 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1299) Pkinase PF00069.20 ETO36401.1 - 1.4e-31 109.6 0.1 3.8e-31 108.1 0.1 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO36401.1 - 3.4e-08 32.8 0.3 0.004 16.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Fis1_TPR_C PF14853.1 ETO36401.1 - 0.058 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Kinase-like PF14531.1 ETO36401.1 - 0.13 11.1 0.0 0.41 9.5 0.0 1.7 2 0 0 2 2 2 0 Kinase-like MA-Mit PF09245.5 ETO36402.1 - 0.079 12.2 2.0 0.1 11.8 1.4 1.3 1 1 0 1 1 1 0 Mycoplasma arthritidis-derived mitogen DUF553 PF04473.7 ETO36402.1 - 0.15 11.3 1.6 0.25 10.6 1.1 1.4 1 1 0 1 1 1 0 Transglutaminase-like domain Brevenin PF03032.10 ETO36404.1 - 0.072 12.9 0.5 0.072 12.9 0.3 2.0 2 0 0 2 2 2 0 Brevenin/esculentin/gaegurin/rugosin family DUF572 PF04502.8 ETO36404.1 - 0.12 11.5 29.1 0.15 11.2 20.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Allexi_40kDa PF05549.6 ETO36404.1 - 0.89 8.8 7.9 1.6 7.9 5.4 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein YL1 PF05764.8 ETO36404.1 - 2.2 7.8 28.6 3.1 7.3 19.8 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Peptidase_S64 PF08192.6 ETO36404.1 - 4.4 5.5 16.3 5.5 5.1 11.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 Dapper PF15268.1 ETO36404.1 - 5.8 5.5 24.7 6.8 5.3 17.1 1.0 1 0 0 1 1 1 0 Dapper Mitofilin PF09731.4 ETO36404.1 - 6.3 5.3 22.4 7.2 5.1 15.5 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein AvrE PF11725.3 ETO36404.1 - 7.5 3.4 18.3 8.5 3.2 12.7 1.0 1 0 0 1 1 1 0 Pathogenicity factor RNase_HII PF01351.13 ETO36405.1 - 2.5e-22 79.5 0.0 3.2e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII DUF4231 PF14015.1 ETO36406.1 - 0.035 14.0 2.6 0.28 11.1 0.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) DUF998 PF06197.8 ETO36406.1 - 0.058 12.7 0.1 0.058 12.7 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF998) BUD22 PF09073.5 ETO36406.1 - 0.082 11.9 0.1 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 BUD22 DUF2301 PF10063.4 ETO36406.1 - 2.4 8.3 7.8 1.3 9.2 0.1 2.6 3 0 0 3 3 3 0 Uncharacterized integral membrane protein (DUF2301) WD40 PF00400.27 ETO36409.1 - 3.5e-21 74.2 9.3 2.9e-11 42.7 0.8 2.6 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO36409.1 - 0.00023 19.4 1.5 0.0048 15.0 0.2 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DKNYY PF13644.1 ETO36409.1 - 0.07 13.4 1.2 0.083 13.1 0.8 1.1 1 0 0 1 1 1 0 DKNYY family DUF4221 PF13970.1 ETO36409.1 - 0.084 12.1 4.5 0.33 10.2 1.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4221) DUF377 PF04041.8 ETO36409.1 - 0.12 11.0 0.2 0.13 10.9 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF377) Methyltransf_15 PF09445.5 ETO36410.1 - 1.6e-38 131.8 0.5 2.8e-38 131.0 0.4 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 ETO36410.1 - 1.6e-09 37.7 0.0 3.2e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 ETO36410.1 - 1e-08 34.9 0.1 2.3e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.1 ETO36410.1 - 3.4e-08 33.2 0.4 9.7e-08 31.7 0.3 1.8 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 ETO36410.1 - 4.9e-07 29.5 0.0 1.4e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 ETO36410.1 - 4.5e-06 27.2 0.0 1.2e-05 25.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETO36410.1 - 3.6e-05 24.0 0.1 0.00018 21.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 ETO36410.1 - 0.002 17.3 0.1 0.002 17.3 0.1 2.9 4 0 0 4 4 3 1 Ribosomal protein L11 methyltransferase (PrmA) ADH_zinc_N PF00107.21 ETO36410.1 - 0.012 15.1 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_11 PF08241.7 ETO36410.1 - 0.026 15.0 0.0 0.086 13.3 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 ETO36410.1 - 0.031 14.7 6.7 2.5 8.6 0.0 3.0 3 0 0 3 3 3 0 Methyltransferase domain Cons_hypoth95 PF03602.10 ETO36410.1 - 0.045 13.1 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DAGK_prokar PF01219.14 ETO36411.1 - 0.15 11.6 1.9 0.25 10.9 1.1 1.6 1 1 0 1 1 1 0 Prokaryotic diacylglycerol kinase RHD3 PF05879.7 ETO36412.1 - 8.4e-10 37.2 1.5 2.9e-09 35.4 0.5 1.7 1 1 1 2 2 2 1 Root hair defective 3 GTP-binding protein (RHD3) YjgP_YjgQ PF03739.9 ETO36412.1 - 0.00025 19.9 2.2 0.00032 19.5 1.6 1.3 1 0 0 1 1 1 1 Predicted permease YjgP/YjgQ family PTB PF08416.8 ETO36413.1 - 0.047 13.5 0.1 2.3 8.1 0.1 2.3 2 0 0 2 2 2 0 Phosphotyrosine-binding domain DUF3764 PF12594.3 ETO36413.1 - 0.3 10.8 1.8 1 9.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3764) G-gamma PF00631.17 ETO36414.1 - 9e-05 22.1 0.1 0.00018 21.2 0.1 1.4 1 0 0 1 1 1 1 GGL domain CENP-L PF13092.1 ETO36418.1 - 0.012 15.3 2.7 0.077 12.7 0.2 2.9 1 1 1 2 2 2 0 Kinetochore complex Sim4 subunit Fta1 Med21 PF11221.3 ETO36418.1 - 0.22 11.4 2.8 0.6 10.0 0.2 2.2 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Secretin_N_2 PF07655.8 ETO36418.1 - 5.7 7.3 17.5 0.5 10.7 8.0 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain UCH PF00443.24 ETO36420.1 - 5.8e-21 74.8 2.4 4.1e-10 39.2 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO36420.1 - 9.1e-08 31.8 1.1 8.5e-07 28.6 0.8 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1279 PF06916.8 ETO36420.1 - 0.04 14.2 0.2 0.082 13.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) Thia_YuaJ PF09515.5 ETO36420.1 - 0.38 10.4 2.5 0.44 10.2 0.0 2.0 2 0 0 2 2 2 0 Thiamine transporter protein (Thia_YuaJ) Sec34 PF04136.10 ETO36422.1 - 0.0023 17.6 0.8 0.0076 15.9 0.6 1.9 1 0 0 1 1 1 1 Sec34-like family Abhydrolase_4 PF08386.5 ETO36422.1 - 0.044 13.6 0.1 2.9 7.8 0.0 2.6 2 0 0 2 2 2 0 TAP-like protein CAP_GLY PF01302.20 ETO36423.1 - 3.1e-25 87.6 10.7 2.2e-12 46.5 1.8 2.3 2 0 0 2 2 2 2 CAP-Gly domain Atg14 PF10186.4 ETO36423.1 - 0.0042 16.0 6.3 0.0065 15.4 4.4 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF4551 PF15087.1 ETO36423.1 - 0.64 8.3 11.6 1 7.6 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ndc1_Nup PF09531.5 ETO36423.1 - 9.4 4.5 11.7 13 4.0 8.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RGS PF00615.14 ETO36424.1 - 0.052 13.6 0.0 0.099 12.7 0.0 1.4 1 0 0 1 1 1 0 Regulator of G protein signaling domain Sod_Cu PF00080.15 ETO36425.1 - 6.7e-26 91.1 3.8 1.4e-17 64.1 0.7 2.4 2 0 0 2 2 2 2 Copper/zinc superoxide dismutase (SODC) UCR_TM PF02921.9 ETO36425.1 - 0.075 13.2 0.5 0.12 12.6 0.3 1.3 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region Aminotran_5 PF00266.14 ETO36426.1 - 2.7e-24 85.6 0.0 3.5e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Tau95 PF09734.4 ETO36430.1 - 0.0086 15.4 0.7 0.0099 15.2 0.5 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit DUF3870 PF12986.2 ETO36430.1 - 2.9 8.1 7.0 2 8.7 0.5 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3870) tRNA_edit PF04073.10 ETO36432.1 - 7.5e-22 77.4 0.0 1.1e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain DMPK_coil PF08826.5 ETO36432.1 - 4.5e-06 26.4 1.4 4.5e-06 26.4 1.0 2.0 2 0 0 2 2 2 1 DMPK coiled coil domain like bZIP_1 PF00170.16 ETO36432.1 - 0.0003 20.6 2.6 0.0085 16.0 0.6 2.5 2 0 0 2 2 2 1 bZIP transcription factor IncA PF04156.9 ETO36432.1 - 0.0066 16.0 3.7 0.0066 16.0 2.6 1.6 2 0 0 2 2 1 1 IncA protein DivIC PF04977.10 ETO36432.1 - 0.0067 15.8 3.0 0.038 13.4 0.9 2.4 2 0 0 2 2 2 1 Septum formation initiator Spc7 PF08317.6 ETO36432.1 - 0.0083 14.8 3.9 0.014 14.1 2.7 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Snapin_Pallidin PF14712.1 ETO36432.1 - 0.0098 16.1 10.4 0.34 11.2 1.6 2.8 2 1 1 3 3 2 2 Snapin/Pallidin V_ATPase_I PF01496.14 ETO36432.1 - 0.01 13.7 1.8 0.011 13.6 1.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prefoldin PF02996.12 ETO36432.1 - 0.012 15.2 4.5 0.87 9.2 0.8 2.5 1 1 1 2 2 2 0 Prefoldin subunit NPV_P10 PF05531.7 ETO36432.1 - 0.015 15.5 3.5 0.044 14.0 1.0 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF972 PF06156.8 ETO36432.1 - 0.017 15.4 1.9 0.017 15.4 1.3 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF972) Myosin_tail_1 PF01576.14 ETO36432.1 - 0.023 12.4 2.5 0.033 11.9 1.8 1.2 1 0 0 1 1 1 0 Myosin tail Med10 PF09748.4 ETO36432.1 - 0.024 14.4 6.2 0.11 12.3 1.5 2.6 1 1 1 2 2 2 0 Transcription factor subunit Med10 of Mediator complex Tropomyosin_1 PF12718.2 ETO36432.1 - 0.03 14.1 1.9 0.03 14.1 1.3 1.9 2 0 0 2 2 2 0 Tropomyosin like Ax_dynein_light PF10211.4 ETO36432.1 - 0.042 13.6 1.6 0.042 13.6 1.1 1.8 2 0 0 2 2 2 0 Axonemal dynein light chain Glu_synthase PF01645.12 ETO36432.1 - 0.045 12.6 0.3 0.072 12.0 0.2 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase APG6 PF04111.7 ETO36432.1 - 0.048 12.7 3.8 0.072 12.1 2.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF262 PF03235.9 ETO36432.1 - 0.076 12.9 3.1 0.15 11.9 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF262 Shugoshin_N PF07558.6 ETO36432.1 - 0.076 12.7 4.6 0.089 12.5 0.5 2.4 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Nup54 PF13874.1 ETO36432.1 - 0.085 12.5 3.2 0.51 10.0 0.5 2.6 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 DUF2408 PF10303.4 ETO36432.1 - 0.1 12.7 4.0 0.064 13.3 1.1 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF2408) bZIP_2 PF07716.10 ETO36432.1 - 0.14 12.0 6.2 0.24 11.2 1.5 2.6 2 0 0 2 2 2 0 Basic region leucine zipper Spc24 PF08286.6 ETO36432.1 - 0.14 11.8 8.3 0.11 12.1 3.6 2.2 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 DivIVA PF05103.8 ETO36432.1 - 0.38 10.7 4.7 6.4 6.8 2.2 2.4 1 1 1 2 2 2 0 DivIVA protein Mis12 PF05859.7 ETO36432.1 - 0.49 10.1 5.0 2.8 7.7 0.0 3.3 2 1 1 3 3 3 0 Mis12 protein FlxA PF14282.1 ETO36432.1 - 0.53 10.2 7.9 0.6 10.0 2.3 2.3 1 1 1 2 2 2 0 FlxA-like protein MerR-DNA-bind PF09278.6 ETO36432.1 - 0.55 10.6 3.5 23 5.4 0.1 2.5 2 0 0 2 2 2 0 MerR, DNA binding HR1 PF02185.11 ETO36432.1 - 1.5 8.5 9.7 13 5.6 4.5 3.4 2 1 0 2 2 2 0 Hr1 repeat AKNA PF12443.3 ETO36432.1 - 2.7 8.0 6.2 2.9 7.9 0.2 3.2 3 1 0 3 3 3 0 AT-hook-containing transcription factor DUF3287 PF11690.3 ETO36432.1 - 3 7.9 5.1 0.94 9.5 0.2 2.5 4 0 0 4 4 3 0 Protein of unknown function (DUF3287) DUF4404 PF14357.1 ETO36432.1 - 4 7.9 7.1 17 5.9 1.6 2.7 2 1 1 3 3 2 0 Domain of unknown function (DUF4404) ABC_tran PF00005.22 ETO36433.1 - 5.1e-24 85.1 0.0 7.9e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 ETO36433.1 - 1.5e-09 37.7 2.3 2.2e-09 37.1 1.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 ETO36433.1 - 0.00099 19.1 0.1 0.38 10.6 0.0 2.2 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 ETO36433.1 - 0.017 14.3 1.0 0.38 9.9 0.1 2.1 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 ETO36433.1 - 0.018 13.6 0.1 0.025 13.1 0.0 1.1 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_29 PF13555.1 ETO36433.1 - 0.11 12.0 0.0 0.48 10.0 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_membrane PF00664.18 ETO36434.1 - 8.4e-05 22.1 0.6 0.0021 17.5 0.4 2.1 1 1 1 2 2 2 2 ABC transporter transmembrane region Ring_hydroxyl_A PF00848.14 ETO36434.1 - 0.18 11.4 0.3 0.24 10.9 0.2 1.2 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) DUF308 PF03729.8 ETO36434.1 - 3.3 7.7 10.1 0.29 11.1 2.7 2.4 3 1 0 3 3 3 0 Short repeat of unknown function (DUF308) Kelch_5 PF13854.1 ETO36435.1 - 0.17 11.9 0.3 4.3 7.4 0.0 2.6 3 0 0 3 3 3 0 Kelch motif Methylase_S PF01420.14 ETO36435.1 - 0.4 10.6 8.3 0.14 12.0 4.0 1.5 2 0 0 2 2 2 0 Type I restriction modification DNA specificity domain WD40 PF00400.27 ETO36436.1 - 3.9e-10 39.1 1.8 0.00032 20.4 0.1 3.1 2 1 0 2 2 2 2 WD domain, G-beta repeat PTEN_C2 PF10409.4 ETO36437.1 - 0.057 13.1 0.4 0.09 12.5 0.2 1.4 1 1 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein EpoR_lig-bind PF09067.5 ETO36437.1 - 0.079 12.9 1.4 0.21 11.6 0.4 1.8 1 1 1 2 2 2 0 Erythropoietin receptor, ligand binding WD40 PF00400.27 ETO36438.1 - 8.3e-46 152.3 20.4 3.8e-10 39.2 0.0 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO36438.1 - 1.8e-10 39.6 1.7 0.00095 17.4 0.1 4.3 2 2 2 4 4 4 4 Nucleoporin Nup120/160 Inos-1-P_synth PF01658.12 ETO36439.1 - 0.0051 16.6 0.1 0.0079 16.0 0.1 1.5 1 1 0 1 1 1 1 Myo-inositol-1-phosphate synthase 14-3-3 PF00244.15 ETO36440.1 - 4.7e-73 245.1 8.1 1.2e-68 230.7 5.6 2.3 1 1 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 ETO36440.1 - 0.018 14.9 0.5 0.43 10.5 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETO36440.1 - 0.1 12.4 5.8 0.17 11.7 1.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETO36440.1 - 4.5 7.4 5.7 4.6 7.3 0.6 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ATP_bind_3 PF01171.15 ETO36441.1 - 1.4e-24 86.5 0.4 1.2e-12 47.7 0.0 3.4 2 1 1 3 3 3 3 PP-loop family tRNA_Me_trans PF03054.11 ETO36441.1 - 0.0097 14.5 0.0 0.017 13.6 0.0 1.4 1 0 0 1 1 1 1 tRNA methyl transferase SR-25 PF10500.4 ETO36441.1 - 0.025 14.0 10.8 0.056 12.8 7.5 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Secretin_N_2 PF07655.8 ETO36441.1 - 1 9.8 28.4 5.8 7.3 6.0 2.7 2 0 0 2 2 2 0 Secretin N-terminal domain G-alpha PF00503.15 ETO36442.1 - 1.2e-25 90.0 0.0 1.6e-25 89.6 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit AAA_PrkA PF08298.6 ETO36442.1 - 0.11 11.1 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain WD40 PF00400.27 ETO36443.1 - 0.009 15.8 0.0 0.036 13.9 0.0 2.1 1 0 0 1 1 1 1 WD domain, G-beta repeat Golgin_A5 PF09787.4 ETO36443.1 - 0.73 8.2 6.1 1.1 7.7 4.2 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 T4SS PF07996.6 ETO36443.1 - 1.3 8.7 4.6 1.3 8.8 1.9 1.7 2 0 0 2 2 2 0 Type IV secretion system proteins DUF1353 PF07087.6 ETO36444.1 - 0.0059 16.0 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1353) CDC45 PF02724.9 ETO36444.1 - 1.1 7.1 12.7 1.5 6.7 8.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.11 ETO36444.1 - 1.1 9.0 8.6 1.8 8.3 6.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.12 ETO36444.1 - 3.1 6.5 6.2 4.1 6.1 4.3 1.3 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.4 ETO36444.1 - 5 5.2 18.1 5.8 5.0 12.6 1.1 1 0 0 1 1 1 0 Transmembrane protein PDZ PF00595.19 ETO36445.1 - 0.12 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) Pkinase PF00069.20 ETO36446.1 - 0.0027 16.8 0.1 0.0059 15.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Fer2 PF00111.22 ETO36446.1 - 0.15 11.7 0.4 0.56 9.9 0.1 2.1 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Mucin PF01456.12 ETO36446.1 - 0.46 10.2 3.7 0.53 10.0 2.6 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein HCO3_cotransp PF00955.16 ETO36447.1 - 0.016 13.8 0.1 0.021 13.5 0.1 1.1 1 0 0 1 1 1 0 HCO3- transporter family KRAP_IP3R_bind PF14722.1 ETO36447.1 - 0.052 13.1 0.1 0.076 12.5 0.0 1.2 1 0 0 1 1 1 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain Colicin_V PF02674.11 ETO36447.1 - 0.1 12.4 3.0 0.16 11.8 2.1 1.3 1 1 0 1 1 1 0 Colicin V production protein NUDIX PF00293.23 ETO36449.1 - 0.013 15.0 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 NUDIX domain DUF1911 PF08929.5 ETO36450.1 - 0.4 11.3 6.4 0.11 13.1 1.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1911) POX PF07526.6 ETO36450.1 - 0.65 10.2 6.7 0.84 9.8 0.3 2.5 2 0 0 2 2 2 0 Associated with HOX DUF4414 PF14377.1 ETO36450.1 - 2.5 8.0 5.8 0.19 11.6 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4414) FA_desaturase PF00487.19 ETO36451.1 - 1.1e-05 24.9 16.4 2.2e-05 24.0 11.4 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Apc4 PF12896.2 ETO36453.1 - 0.029 13.6 0.2 0.053 12.8 0.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 DAG1 PF05454.6 ETO36455.1 - 0.00018 20.7 0.0 0.00022 20.4 0.0 1.1 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Protocadherin PF08374.6 ETO36455.1 - 0.00038 20.1 0.0 0.00053 19.6 0.0 1.1 1 0 0 1 1 1 1 Protocadherin Herpes_gE PF02480.11 ETO36455.1 - 0.00044 18.6 0.0 0.00057 18.2 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF1510 PF07423.6 ETO36455.1 - 0.0006 19.2 0.1 0.00093 18.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) SKG6 PF08693.5 ETO36455.1 - 0.00065 18.9 0.7 0.0014 17.9 0.5 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF3341 PF11821.3 ETO36455.1 - 0.00074 19.0 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3341) TMEM154 PF15102.1 ETO36455.1 - 0.0014 18.3 3.2 0.0026 17.4 2.2 1.7 1 1 0 1 1 1 1 TMEM154 protein family CD34_antigen PF06365.7 ETO36455.1 - 0.0034 17.0 0.2 0.0058 16.3 0.1 1.4 1 1 0 1 1 1 1 CD34/Podocalyxin family DUF1049 PF06305.6 ETO36455.1 - 0.004 16.5 0.0 0.0074 15.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1049) m04gp34like PF12216.3 ETO36455.1 - 0.0041 16.5 1.4 0.0066 15.8 0.9 1.4 1 1 0 1 1 1 1 Immune evasion protein Baculo_E56 PF04639.7 ETO36455.1 - 0.0074 14.9 0.1 0.01 14.5 0.1 1.3 1 0 0 1 1 1 1 Baculoviral E56 protein, specific to ODV envelope Herpes_glycop PF01528.11 ETO36455.1 - 0.01 14.5 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein M DUF3753 PF12575.3 ETO36455.1 - 0.011 15.5 0.6 0.011 15.5 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) LRR19-TM PF15176.1 ETO36455.1 - 0.011 15.3 0.2 0.02 14.5 0.2 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain HemY_N PF07219.8 ETO36455.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 HemY protein N-terminus Peptidase_M56 PF05569.6 ETO36455.1 - 0.022 13.7 0.4 0.027 13.4 0.2 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 Shisa PF13908.1 ETO36455.1 - 0.023 14.8 0.7 0.032 14.3 0.0 1.6 2 0 0 2 2 1 0 Wnt and FGF inhibitory regulator SIT PF15330.1 ETO36455.1 - 0.023 14.8 0.0 0.052 13.6 0.0 1.6 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF4448 PF14610.1 ETO36455.1 - 0.024 14.1 0.8 0.026 14.0 0.1 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF4448) DUF4446 PF14584.1 ETO36455.1 - 0.031 14.1 0.7 0.047 13.5 0.1 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF4446) DUF4381 PF14316.1 ETO36455.1 - 0.032 14.3 0.1 0.062 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) LRRC37AB_C PF14914.1 ETO36455.1 - 0.032 13.6 0.4 0.054 12.9 0.2 1.3 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Sarcoglycan_2 PF05510.8 ETO36455.1 - 0.035 12.4 0.1 0.074 11.3 0.0 1.6 2 0 0 2 2 2 0 Sarcoglycan alpha/epsilon Use1 PF09753.4 ETO36455.1 - 0.048 13.1 0.1 0.068 12.6 0.1 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 Glyco_transf_22 PF03901.12 ETO36455.1 - 0.048 12.6 1.0 0.062 12.2 0.7 1.1 1 0 0 1 1 1 0 Alg9-like mannosyltransferase family DUF3827 PF12877.2 ETO36455.1 - 0.048 11.7 1.3 0.064 11.3 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Amnionless PF14828.1 ETO36455.1 - 0.062 11.7 0.0 0.07 11.6 0.0 1.1 1 0 0 1 1 1 0 Amnionless EphA2_TM PF14575.1 ETO36455.1 - 0.073 13.4 0.1 0.15 12.5 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Vpu PF00558.14 ETO36455.1 - 0.1 12.1 0.4 0.18 11.3 0.3 1.4 1 0 0 1 1 1 0 Vpu protein MLANA PF14991.1 ETO36455.1 - 0.18 11.8 0.5 0.31 11.0 0.3 1.5 1 1 0 1 1 1 0 Protein melan-A ODV-E18 PF10717.4 ETO36455.1 - 0.19 11.2 2.7 0.2 11.1 0.6 1.9 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Sigma_reg_N PF13800.1 ETO36455.1 - 0.4 10.7 3.1 0.25 11.3 0.7 1.8 2 0 0 2 2 1 0 Sigma factor regulator N-terminal Rifin_STEVOR PF02009.11 ETO36455.1 - 0.91 9.1 8.3 1.8 8.1 5.9 1.3 1 1 0 1 1 1 0 Rifin/stevor family Synaptobrevin PF00957.16 ETO36455.1 - 1.4 8.5 5.1 0.37 10.4 0.8 2.0 2 0 0 2 2 2 0 Synaptobrevin DUF912 PF06024.7 ETO36455.1 - 3.3 7.8 7.4 1.7 8.7 3.6 1.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) RXT2_N PF08595.6 ETO36456.1 - 0.074 12.8 1.6 0.1 12.3 1.0 1.3 1 1 0 1 1 1 0 RXT2-like, N-terminal Iron_permease PF04120.7 ETO36460.1 - 0.022 14.3 0.7 0.055 13.0 0.5 1.6 1 0 0 1 1 1 0 Low affinity iron permease Mito_fiss_reg PF05308.6 ETO36460.1 - 0.05 12.9 40.2 0.049 13.0 8.5 3.6 3 0 0 3 3 3 0 Mitochondrial fission regulator Ctr PF04145.10 ETO36461.1 - 0.02 14.9 1.6 0.52 10.3 0.1 2.5 2 0 0 2 2 2 0 Ctr copper transporter family Menin PF05053.8 ETO36461.1 - 0.55 8.3 14.0 0.97 7.5 9.6 1.5 1 1 0 1 1 1 0 Menin FAM176 PF14851.1 ETO36461.1 - 1 8.9 6.1 1.5 8.4 0.3 2.3 2 0 0 2 2 2 0 FAM176 family tRNA_synt_1c_R2 PF04557.10 ETO36461.1 - 2.1 9.1 8.3 9.5 7.0 3.4 2.6 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Eapp_C PF10238.4 ETO36461.1 - 3.8 7.4 17.6 0.89 9.4 6.6 2.6 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF957 PF06117.6 ETO36462.1 - 0.077 12.5 0.2 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Enterobacterial protein of unknown function (DUF957) PRK PF00485.13 ETO36463.1 - 1.2e-06 28.1 0.0 0.046 13.2 0.0 2.2 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family DnaJ PF00226.26 ETO36464.1 - 2e-09 37.0 1.8 0.0002 20.9 0.1 2.9 1 1 1 2 2 2 2 DnaJ domain adh_short PF00106.20 ETO36465.1 - 4.5e-30 104.7 0.0 5.5e-30 104.4 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETO36465.1 - 5.6e-12 45.9 0.0 7e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETO36465.1 - 5.4e-11 42.4 0.0 7.7e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETO36465.1 - 0.0022 17.4 0.1 0.0026 17.2 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETO36465.1 - 0.0057 15.3 0.5 0.0072 15.0 0.3 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 ETO36465.1 - 0.034 14.0 0.1 0.055 13.3 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Peptidase_U57 PF05582.7 ETO36465.1 - 0.05 12.5 0.1 0.065 12.1 0.1 1.1 1 0 0 1 1 1 0 YabG peptidase U57 AdoHcyase_NAD PF00670.16 ETO36465.1 - 0.065 13.0 0.2 0.097 12.5 0.1 1.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_10 PF13460.1 ETO36465.1 - 0.089 12.7 0.3 0.15 12.0 0.2 1.3 1 1 0 1 1 1 0 NADH(P)-binding DsrD PF08679.6 ETO36465.1 - 2.5 8.1 5.0 21 5.1 0.7 2.6 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) WD40 PF00400.27 ETO36466.1 - 3.6e-05 23.4 2.4 6.2e-05 22.7 0.3 2.4 3 0 0 3 3 3 1 WD domain, G-beta repeat Glycos_transf_1 PF00534.15 ETO36466.1 - 0.029 13.7 3.2 0.049 13.0 2.2 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 RNA_pol_Rpb1_5 PF04998.12 ETO36466.1 - 0.34 10.1 3.3 0.5 9.5 2.3 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF3687 PF12459.3 ETO36467.1 - 0.1 11.8 1.9 0.2 10.9 1.3 1.5 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein Phage_tube PF04985.9 ETO36468.1 - 0.056 12.8 0.5 0.47 9.8 0.1 1.9 2 0 0 2 2 2 0 Phage tail tube protein FII zf-TRAF PF02176.13 ETO36470.1 - 0.014 15.7 5.8 0.014 15.7 4.0 2.7 2 1 0 2 2 2 0 TRAF-type zinc finger DUF3629 PF12302.3 ETO36470.1 - 0.023 14.0 3.0 0.037 13.3 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) DUF342 PF03961.8 ETO36470.1 - 4.8 5.4 10.9 6.9 4.9 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) ICAT PF06384.6 ETO36471.1 - 0.083 12.6 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Beta-catenin-interacting protein ICAT F-112 PF09645.5 ETO36471.1 - 0.11 12.3 0.3 0.14 12.0 0.2 1.1 1 0 0 1 1 1 0 F-112 protein RtcB PF01139.12 ETO36472.1 - 0.019 13.9 0.0 0.025 13.6 0.0 1.1 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB PRONE PF03759.8 ETO36472.1 - 0.066 11.7 0.3 0.077 11.5 0.2 1.1 1 0 0 1 1 1 0 PRONE (Plant-specific Rop nucleotide exchanger) CcdA PF07362.7 ETO36472.1 - 0.069 13.0 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA HOK_GEF PF01848.11 ETO36472.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Hok/gef family zf-RING_2 PF13639.1 ETO36473.1 - 2.3e-07 30.5 5.3 2.3e-07 30.5 3.7 2.1 2 0 0 2 2 2 1 Ring finger domain SWIM PF04434.12 ETO36473.1 - 7.4e-05 22.1 0.2 0.00015 21.1 0.1 1.6 1 0 0 1 1 1 1 SWIM zinc finger PHD PF00628.24 ETO36473.1 - 0.00019 21.0 9.6 0.0005 19.7 6.7 1.8 1 0 0 1 1 1 1 PHD-finger zf-Apc11 PF12861.2 ETO36473.1 - 0.00042 20.1 3.0 0.001 18.8 2.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 ETO36473.1 - 0.0016 18.3 4.4 0.0044 16.9 3.1 1.8 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_2 PF13923.1 ETO36473.1 - 0.0026 17.7 5.8 0.0076 16.2 4.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETO36473.1 - 0.11 12.5 4.5 0.32 11.1 3.1 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger C1_1 PF00130.17 ETO36473.1 - 0.35 10.6 9.2 0.13 11.9 3.7 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_4 PF14570.1 ETO36473.1 - 1 8.9 12.2 0.042 13.4 4.3 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.20 ETO36473.1 - 1.6 8.4 6.5 5.1 6.8 4.5 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CAP PF00188.21 ETO36474.1 - 6.3e-06 26.6 0.3 1.4e-05 25.5 0.2 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PT PF04886.7 ETO36474.1 - 1.5e-05 24.2 25.3 0.00015 20.9 3.1 3.4 2 1 1 3 3 3 2 PT repeat DUF4106 PF13388.1 ETO36474.1 - 0.0017 17.4 1.2 0.0027 16.7 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) MobA_MobL PF03389.10 ETO36475.1 - 0.0032 16.8 0.0 0.0047 16.3 0.0 1.2 1 0 0 1 1 1 1 MobA/MobL family NAD_binding_2 PF03446.10 ETO36477.1 - 0.13 12.0 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase zf-RVT PF13966.1 ETO36478.1 - 0.00013 22.2 0.2 0.00013 22.2 0.2 2.5 3 0 0 3 3 3 1 zinc-binding in reverse transcriptase zf-CCHC PF00098.18 ETO36479.1 - 0.0019 18.0 1.9 0.0045 16.8 1.3 1.7 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.22 ETO36481.1 - 6.6e-06 25.6 0.1 7.6e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dicty_CAD PF05720.7 ETO36484.1 - 0.056 13.0 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 Cell-cell adhesion domain FYVE_2 PF02318.11 ETO36485.1 - 0.029 14.2 1.3 0.029 14.2 0.9 1.9 1 1 1 2 2 2 0 FYVE-type zinc finger Cyt-b5 PF00173.23 ETO36486.1 - 0.00041 20.0 0.0 2.4 8.0 0.0 3.2 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain DUF3074 PF11274.3 ETO36487.1 - 0.009 15.6 0.8 0.01 15.4 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) FYDLN_acid PF09538.5 ETO36487.1 - 1.1 9.8 13.8 1.6 9.3 9.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) SH3_1 PF00018.23 ETO36490.1 - 1.9e-09 36.7 0.0 4.4e-09 35.5 0.0 1.6 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 ETO36490.1 - 1.9e-06 27.3 0.0 3.5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 ETO36490.1 - 0.00029 20.2 0.0 0.00053 19.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain GHL6 PF14871.1 ETO36491.1 - 0.049 13.6 0.0 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 DUF3164 PF11363.3 ETO36493.1 - 0.025 13.9 0.1 0.039 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3164) ALMT PF11744.3 ETO36493.1 - 0.15 10.7 1.3 0.16 10.5 0.6 1.3 1 1 0 1 1 1 0 Aluminium activated malate transporter F-box-like PF12937.2 ETO36494.1 - 0.0015 18.1 0.2 0.0031 17.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like SPRY PF00622.23 ETO36495.1 - 3.5e-08 33.5 0.2 4.8e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 SPRY domain UQ_con PF00179.21 ETO36496.1 - 0.00036 19.9 0.4 0.00058 19.3 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CYTL1 PF15153.1 ETO36496.1 - 0.087 12.5 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Cytokine-like protein 1 GED PF02212.13 ETO36496.1 - 0.09 12.6 0.1 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Dynamin GTPase effector domain HTH_26 PF13443.1 ETO36497.1 - 0.04 14.1 0.2 0.12 12.6 0.1 1.8 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain NADH_dh_m_C1 PF15088.1 ETO36498.1 - 0.092 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial TFIIA PF03153.8 ETO36499.1 - 0.0033 17.3 23.7 0.006 16.5 16.4 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit EHN PF06441.7 ETO36499.1 - 2 8.4 7.4 0.52 10.2 2.2 2.2 2 1 0 2 2 2 0 Epoxide hydrolase N terminus Nop14 PF04147.7 ETO36499.1 - 3.3 5.5 30.9 0.027 12.4 14.5 1.9 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.9 ETO36499.1 - 3.4 5.6 24.8 0.052 11.5 9.0 2.2 2 0 0 2 2 2 0 CDC45-like protein Vfa1 PF08432.5 ETO36499.1 - 8 6.4 18.9 1.9 8.4 5.4 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 SART-1 PF03343.8 ETO36501.1 - 7.7e-55 186.3 56.9 1.6e-29 102.7 14.4 3.6 2 1 1 3 3 3 3 SART-1 family SAM_2 PF07647.12 ETO36501.1 - 1.8e-05 24.5 0.1 4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETO36501.1 - 2.3e-05 24.4 0.1 5.8e-05 23.1 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kei1 PF08552.6 ETO36501.1 - 0.0011 18.6 7.9 0.53 9.9 0.0 3.6 2 2 2 4 4 4 2 Inositolphosphorylceramide synthase subunit Kei1 YMF19 PF02326.10 ETO36501.1 - 0.042 14.4 5.2 4.2 7.9 0.3 4.3 3 1 0 3 3 3 0 Plant ATP synthase F0 DUF4131 PF13567.1 ETO36501.1 - 0.2 11.0 0.0 0.51 9.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF1352 PF07086.7 ETO36501.1 - 1.4 8.4 5.5 5.8 6.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1352) Aminotran_5 PF00266.14 ETO36502.1 - 4.8e-33 114.3 0.0 1.8e-32 112.5 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V ATP_bind_3 PF01171.15 ETO36502.1 - 4.3e-16 58.9 0.0 2.3e-15 56.5 0.0 2.2 2 1 0 2 2 2 1 PP-loop family CS PF04969.11 ETO36503.1 - 3.8e-15 56.1 0.1 1.4e-14 54.3 0.0 2.1 1 0 0 1 1 1 1 CS domain CUE PF02845.11 ETO36503.1 - 0.061 12.8 0.7 0.13 11.7 0.5 1.6 1 0 0 1 1 1 0 CUE domain Mitofilin PF09731.4 ETO36503.1 - 0.14 10.7 13.4 0.21 10.1 9.3 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Lsr2 PF11774.3 ETO36503.1 - 0.53 10.2 3.2 0.3 11.0 0.4 1.9 1 1 1 2 2 2 0 Lsr2 Dicty_REP PF05086.7 ETO36503.1 - 0.88 7.2 9.7 1.5 6.5 6.7 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Neur_chan_memb PF02932.11 ETO36503.1 - 2.5 7.9 7.4 0.43 10.4 2.0 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DEAD PF00270.24 ETO36505.1 - 0.0013 18.2 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_29 PF13555.1 ETO36505.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain O-antigen_lig PF13425.1 ETO36506.1 - 0.0015 18.5 1.3 0.0025 17.8 0.2 1.8 2 0 0 2 2 2 1 O-antigen ligase like membrane protein Senescence_reg PF04520.8 ETO36506.1 - 0.011 16.2 2.4 3.6 8.0 1.2 2.1 2 0 0 2 2 2 0 Senescence regulator Wzy_C PF04932.10 ETO36506.1 - 0.093 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 O-Antigen ligase PAP2 PF01569.16 ETO36506.1 - 0.26 10.9 2.4 12 5.5 1.0 2.3 2 0 0 2 2 2 0 PAP2 superfamily OATP PF03137.15 ETO36506.1 - 2.5 6.0 7.8 11 3.8 5.3 1.9 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family PARP PF00644.15 ETO36507.1 - 0.05 13.0 1.3 0.73 9.2 0.9 2.5 1 1 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain Ribosomal_60s PF00428.14 ETO36507.1 - 7 7.1 12.3 7 7.1 7.3 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein bZIP_1 PF00170.16 ETO36508.1 - 0.0025 17.7 18.7 0.98 9.4 0.4 3.8 2 1 1 3 3 3 3 bZIP transcription factor ADIP PF11559.3 ETO36508.1 - 0.012 15.5 19.3 0.012 15.5 13.4 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1192 PF06698.6 ETO36508.1 - 0.021 14.6 9.0 0.12 12.1 0.2 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1192) TMF_DNA_bd PF12329.3 ETO36508.1 - 0.024 14.4 8.9 0.024 14.4 6.2 3.6 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Rootletin PF15035.1 ETO36508.1 - 0.1 12.6 31.3 0.66 9.9 13.0 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF2205 PF10224.4 ETO36508.1 - 0.19 11.3 19.6 0.03 13.9 6.2 2.8 1 1 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) WXG100 PF06013.7 ETO36508.1 - 0.53 10.3 11.3 0.23 11.4 1.0 2.8 3 0 0 3 3 3 0 Proteins of 100 residues with WXG TSC22 PF01166.13 ETO36508.1 - 0.68 9.9 16.4 2 8.4 0.8 3.7 2 1 2 4 4 4 0 TSC-22/dip/bun family Ax_dynein_light PF10211.4 ETO36508.1 - 1 9.1 22.5 0.094 12.5 5.3 2.6 1 1 1 2 2 2 0 Axonemal dynein light chain Tropomyosin_1 PF12718.2 ETO36508.1 - 1.1 9.1 32.3 0.06 13.1 16.8 2.4 1 1 1 2 2 2 0 Tropomyosin like bZIP_2 PF07716.10 ETO36508.1 - 1.2 9.0 43.5 0.26 11.1 3.4 4.3 4 1 1 5 5 3 0 Basic region leucine zipper DUF3552 PF12072.3 ETO36508.1 - 1.7 7.7 28.0 0.21 10.7 10.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Mnd1 PF03962.10 ETO36508.1 - 1.8 8.1 24.3 0.045 13.4 9.7 2.2 1 1 1 2 2 2 0 Mnd1 family Syntaxin-6_N PF09177.6 ETO36508.1 - 1.9 8.9 20.6 0.29 11.5 7.0 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF904 PF06005.7 ETO36508.1 - 2.1 8.7 39.2 1.9 8.8 3.5 4.2 1 1 2 3 3 3 0 Protein of unknown function (DUF904) Spc7 PF08317.6 ETO36508.1 - 2.1 6.9 23.5 2.8 6.5 16.1 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.10 ETO36508.1 - 2.2 7.8 32.2 0.3 10.6 2.6 3.8 4 1 0 4 4 4 0 Septum formation initiator Cep57_CLD_2 PF14197.1 ETO36508.1 - 2.2 8.2 32.7 0.34 10.9 13.5 4.0 1 1 3 4 4 4 0 Centrosome localisation domain of PPC89 Osmo_CC PF08946.5 ETO36508.1 - 3.1 7.9 20.2 0.12 12.3 2.6 3.6 3 0 0 3 3 3 0 Osmosensory transporter coiled coil bZIP_Maf PF03131.12 ETO36508.1 - 4.5 7.6 24.9 9.5 6.5 3.1 2.7 1 1 1 2 2 2 0 bZIP Maf transcription factor IncA PF04156.9 ETO36508.1 - 4.5 6.8 32.1 7.8 6.0 12.1 2.6 1 1 1 2 2 2 0 IncA protein DUF724 PF05266.9 ETO36508.1 - 5.3 6.6 18.3 6.7 6.2 11.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DivIVA PF05103.8 ETO36508.1 - 7.5 6.6 23.2 2.2 8.3 4.1 2.7 1 1 2 3 3 3 0 DivIVA protein FlaC_arch PF05377.6 ETO36508.1 - 7.6 6.5 11.9 21 5.0 0.1 3.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) APG6 PF04111.7 ETO36508.1 - 7.8 5.4 29.4 5.1 6.0 17.5 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Tnp_P_element PF12017.3 ETO36508.1 - 8.7 5.4 13.5 2.5 7.2 2.3 2.2 1 1 1 2 2 2 0 Transposase protein Herpes_BLRF2 PF05812.7 ETO36508.1 - 8.8 6.1 22.3 1.1 9.0 2.9 3.7 1 1 3 4 4 4 0 Herpesvirus BLRF2 protein DUF4140 PF13600.1 ETO36508.1 - 9.3 6.7 16.8 3.2 8.2 4.4 2.7 1 1 2 3 3 2 0 N-terminal domain of unknown function (DUF4140) CheR PF01739.13 ETO36509.1 - 0.015 14.6 0.3 0.2 10.9 0.0 2.1 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain VPS9 PF02204.13 ETO36510.1 - 0.09 12.8 0.2 0.09 12.8 0.1 2.1 3 0 0 3 3 3 0 Vacuolar sorting protein 9 (VPS9) domain Menin PF05053.8 ETO36510.1 - 2.1 6.4 18.6 3.7 5.5 12.9 1.3 1 0 0 1 1 1 0 Menin NRDE-2 PF08424.5 ETO36510.1 - 9 5.0 14.3 12 4.6 7.2 2.2 2 0 0 2 2 2 0 NRDE-2, necessary for RNA interference DUF4518 PF15008.1 ETO36511.1 - 0.0054 15.7 1.8 0.0062 15.6 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4518) CENP-K PF11802.3 ETO36511.1 - 0.033 13.4 2.8 0.044 13.0 1.9 1.3 1 1 0 1 1 1 0 Centromere-associated protein K Ribosomal_L18_c PF14204.1 ETO36511.1 - 0.039 14.5 0.6 0.059 13.9 0.4 1.4 1 1 0 1 1 1 0 Ribosomal L18 C-terminal region DUF2765 PF10963.3 ETO36511.1 - 0.04 13.8 0.1 0.11 12.3 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2765) DNA_ligase_A_N PF04675.9 ETO36511.1 - 0.047 13.4 0.2 0.06 13.1 0.2 1.1 1 0 0 1 1 1 0 DNA ligase N terminus DUF2833 PF11090.3 ETO36511.1 - 0.058 13.5 0.2 0.13 12.4 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2833) DNA_pack_N PF02500.10 ETO36511.1 - 0.51 9.8 7.4 0.9 9.0 2.1 2.0 1 1 1 2 2 2 0 Probable DNA packing protein, N-terminus Macoilin PF09726.4 ETO36512.1 - 7.2 4.7 14.7 7.7 4.6 10.2 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF21 PF01595.15 ETO36513.1 - 1.5e-24 86.3 4.9 6.5e-24 84.2 3.4 1.8 1 1 0 1 1 1 1 Domain of unknown function DUF21 DUF2797 PF10977.3 ETO36515.1 - 0.09 12.3 0.8 0.12 12.0 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) YqbF PF14553.1 ETO36515.1 - 0.14 11.8 2.0 0.15 11.7 0.2 1.9 2 0 0 2 2 2 0 YqbF, hypothetical protein domain PH_10 PF15411.1 ETO36515.1 - 0.81 9.8 5.5 0.88 9.7 1.9 2.0 1 1 1 2 2 2 0 Pleckstrin homology domain EAF PF09816.4 ETO36516.1 - 2.4e-06 27.4 0.0 2.4e-06 27.4 0.0 3.2 3 1 0 3 3 3 1 RNA polymerase II transcription elongation factor Surp PF01805.15 ETO36517.1 - 7e-10 38.4 0.1 1.4e-09 37.4 0.1 1.6 1 0 0 1 1 1 1 Surp module RNA12 PF10443.4 ETO36518.1 - 0.00064 18.3 0.1 0.0022 16.5 0.0 2.1 1 1 0 1 1 1 1 RNA12 protein AAA_22 PF13401.1 ETO36518.1 - 0.0023 18.0 0.0 0.011 15.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 ETO36518.1 - 0.005 16.5 0.1 0.067 12.8 0.0 2.6 2 1 0 2 2 2 1 Archaeal ATPase AAA_14 PF13173.1 ETO36518.1 - 0.0066 16.3 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF2852 PF11014.3 ETO36518.1 - 0.042 13.8 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) RRM_1 PF00076.17 ETO36519.1 - 5.1e-09 35.6 0.0 0.0023 17.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO36519.1 - 3.5e-08 33.3 0.0 0.0044 16.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETO36519.1 - 0.093 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Pkinase PF00069.20 ETO36520.1 - 1.8e-13 50.2 0.0 2.9e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO36520.1 - 3.4e-08 32.8 0.0 5e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 ETO36521.1 - 7.3e-08 31.8 0.0 1.1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO36521.1 - 0.0011 18.0 0.0 0.0017 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.11 ETO36521.1 - 0.094 12.6 0.0 0.18 11.8 0.0 1.5 1 1 0 1 1 1 0 ABC1 family Lge1 PF11488.3 ETO36522.1 - 0.014 15.6 1.7 0.3 11.3 0.7 2.6 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 SQS_PSY PF00494.14 ETO36523.1 - 2.9e-25 89.0 0.2 4.3e-25 88.5 0.1 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase DEC-1_N PF04625.8 ETO36524.1 - 0.14 10.7 0.2 0.16 10.5 0.1 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region WD40 PF00400.27 ETO36526.1 - 9.9e-29 98.1 15.1 8.7e-11 41.2 0.3 5.4 5 1 1 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO36526.1 - 2.5e-05 22.6 3.5 0.62 8.1 0.1 3.6 1 1 1 3 3 3 3 Nucleoporin Nup120/160 DUF851 PF05867.6 ETO36526.1 - 0.12 11.6 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF851) HAD PF12710.2 ETO36526.1 - 0.26 11.4 1.6 2.3 8.3 0.1 2.3 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase CDP-OH_P_transf PF01066.16 ETO36527.1 - 2.3e-13 50.3 3.1 2.3e-13 50.3 2.1 3.4 2 2 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Peptidase_C8 PF03569.8 ETO36528.1 - 0.014 14.6 0.1 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C8 N_Asn_amidohyd PF14736.1 ETO36528.1 - 0.033 13.0 0.0 0.033 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein N-terminal asparagine amidohydrolase Sigma70_r1_1 PF03979.9 ETO36528.1 - 0.052 13.4 5.2 0.069 13.0 3.6 1.2 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 DUF4564 PF15169.1 ETO36528.1 - 0.12 12.1 1.4 0.13 12.0 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4564) Syncollin PF15138.1 ETO36529.1 - 0.062 13.2 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Syncollin DUF413 PF04219.7 ETO36529.1 - 0.081 12.6 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF S_layer_N PF05123.7 ETO36530.1 - 0.16 11.5 2.3 0.19 11.3 1.6 1.1 1 0 0 1 1 1 0 S-layer like family, N-terminal region RRF PF01765.14 ETO36530.1 - 6.5 6.1 8.8 1.2 8.5 0.0 2.8 1 1 2 3 3 3 0 Ribosome recycling factor GP41 PF00517.12 ETO36533.1 - 0.064 12.8 0.0 0.08 12.4 0.0 1.2 1 0 0 1 1 1 0 Retroviral envelope protein WD40 PF00400.27 ETO36534.1 - 1.6e-25 88.0 3.9 8.8e-11 41.2 0.1 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO36534.1 - 0.00029 19.1 0.0 0.052 11.6 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Alpha-L-AF_C PF06964.7 ETO36534.1 - 0.032 14.0 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase C-terminus Nucleoporin_N PF08801.6 ETO36534.1 - 0.051 12.3 1.5 1.5 7.4 0.9 2.5 1 1 1 2 2 2 0 Nup133 N terminal like Transposase_mut PF00872.13 ETO36535.1 - 1.7e-94 316.4 0.0 2e-94 316.2 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.4 ETO36535.1 - 2e-12 47.1 0.0 3.9e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_IS240 PF13610.1 ETO36535.1 - 0.016 15.1 0.6 0.039 13.9 0.4 1.7 1 1 0 1 1 1 0 DDE domain A_thal_3526 PF09713.5 ETO36536.1 - 0.056 13.5 0.0 0.22 11.6 0.0 2.1 2 0 0 2 2 2 0 Plant protein 1589 of unknown function (A_thal_3526) NPV_P10 PF05531.7 ETO36536.1 - 0.14 12.4 19.0 1.5 9.1 0.3 4.3 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein ORF6N PF10543.4 ETO36537.1 - 0.0079 16.2 1.0 0.0079 16.2 0.7 1.9 2 0 0 2 2 2 1 ORF6N domain DUF1635 PF07795.6 ETO36537.1 - 0.016 14.6 1.5 0.018 14.4 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) FliX PF10768.4 ETO36537.1 - 0.063 13.4 1.9 0.068 13.3 1.3 1.1 1 0 0 1 1 1 0 Class II flagellar assembly regulator UPF0261 PF06792.6 ETO36537.1 - 0.081 11.3 0.2 0.087 11.2 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) T4SS-DNA_transf PF02534.9 ETO36537.1 - 0.12 10.9 2.5 0.13 10.7 1.7 1.0 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Sox_N PF12444.3 ETO36537.1 - 0.17 13.0 5.5 0.24 12.5 3.8 1.2 1 0 0 1 1 1 0 Sox developmental protein N terminal Sec62 PF03839.11 ETO36537.1 - 0.74 9.1 5.4 0.8 9.0 3.7 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 CMS1 PF14617.1 ETO36537.1 - 1.4 7.9 8.8 1.7 7.6 6.1 1.0 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit G-patch_2 PF12656.2 ETO36537.1 - 1.4 8.7 4.7 8.2 6.3 3.2 2.0 1 1 0 1 1 1 0 DExH-box splicing factor binding site Tho2 PF11262.3 ETO36537.1 - 5.8 5.8 9.2 8 5.4 6.4 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF3464 PF11947.3 ETO36537.1 - 9.9 5.6 7.1 11 5.4 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) PTEN_C2 PF10409.4 ETO36538.1 - 8.3e-09 35.2 0.3 1.8e-08 34.1 0.2 1.5 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Glyco_transf_34 PF05637.7 ETO36539.1 - 5.6e-05 22.7 0.0 7.7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family NUDIX PF00293.23 ETO36540.1 - 2.8e-13 49.6 0.1 1.8e-06 27.5 0.0 2.3 2 0 0 2 2 2 2 NUDIX domain MAD PF05557.8 ETO36542.1 - 0.0041 15.2 0.6 0.0047 15.0 0.4 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Imm36 PF15597.1 ETO36542.1 - 0.051 13.7 0.4 0.094 12.8 0.2 1.6 1 1 1 2 2 2 0 Immunity protein 36 DUF848 PF05852.6 ETO36542.1 - 0.38 10.5 2.9 0.25 11.1 0.7 1.6 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) EF-hand_2 PF09068.6 ETO36543.1 - 0.021 14.8 0.2 0.065 13.2 0.2 1.8 1 1 0 1 1 1 0 EF hand AAA PF00004.24 ETO36543.1 - 0.023 14.8 0.0 0.046 13.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETO36543.1 - 0.045 13.9 0.1 0.56 10.3 0.0 2.3 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 ETO36543.1 - 0.059 12.3 0.0 0.084 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ICAT PF06384.6 ETO36545.1 - 0.051 13.3 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Beta-catenin-interacting protein ICAT WD40 PF00400.27 ETO36546.1 - 1.3e-165 532.1 38.0 2.9e-13 49.1 0.1 15.1 15 0 0 15 15 15 15 WD domain, G-beta repeat Nup160 PF11715.3 ETO36546.1 - 1.1e-17 63.4 25.3 0.35 8.9 0.1 12.7 1 1 9 12 12 12 8 Nucleoporin Nup120/160 Str_synth PF03088.11 ETO36546.1 - 1e-08 35.0 0.5 0.77 9.8 0.0 7.5 6 2 1 8 8 8 1 Strictosidine synthase Mid2 PF04478.7 ETO36546.1 - 9.4e-07 28.3 11.9 2.9 7.2 0.0 8.5 8 2 2 10 10 10 2 Mid2 like cell wall stress sensor NYD-SP28_assoc PF14775.1 ETO36546.1 - 2.4e-06 27.1 5.0 39 4.0 0.0 9.5 11 0 0 11 11 11 0 Sperm tail C-terminal domain PD40 PF07676.7 ETO36546.1 - 1.2e-05 24.8 15.3 7.6 6.3 0.0 8.4 9 0 0 9 9 9 2 WD40-like Beta Propeller Repeat Peptidase_C69 PF03577.10 ETO36546.1 - 2e-05 23.6 0.6 2 7.1 0.0 5.4 6 0 0 6 6 6 1 Peptidase family C69 DPPIV_N PF00930.16 ETO36546.1 - 0.00028 19.5 0.6 3.3 6.2 0.0 5.5 2 2 3 6 6 6 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Cytochrom_D1 PF02239.11 ETO36546.1 - 0.00051 18.4 11.9 0.57 8.4 0.0 5.8 2 2 4 7 7 7 2 Cytochrome D1 heme domain Resistin PF06954.6 ETO36546.1 - 0.0006 20.0 0.0 10 6.5 0.0 4.4 4 0 0 4 4 4 0 Resistin PLD_C PF12357.3 ETO36546.1 - 0.0046 16.4 0.3 95 2.6 0.0 6.9 9 0 0 9 9 9 0 Phospholipase D C terminal Invas_SpaK PF03519.9 ETO36546.1 - 0.036 13.9 2.0 4.4 7.2 0.0 3.9 4 0 0 4 4 4 0 Invasion protein B family Tagatose_6_P_K PF08013.6 ETO36546.1 - 0.037 12.4 0.0 24 3.1 0.0 3.8 5 0 0 5 5 5 0 Tagatose 6 phosphate kinase DUF1938 PF09153.5 ETO36546.1 - 0.051 13.3 4.6 15 5.4 0.1 4.7 5 1 1 6 6 5 0 Domain of unknown function (DUF1938) DUF4073 PF13285.1 ETO36546.1 - 0.14 11.6 0.0 25 4.2 0.0 4.0 4 1 1 5 5 5 0 Domain of unknown function (DUF4073) WD40 PF00400.27 ETO36547.1 - 8.1e-35 117.4 5.2 1.4e-10 40.6 0.5 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO36547.1 - 4.1e-08 31.8 1.9 6.6e-06 24.5 0.2 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Kelch_5 PF13854.1 ETO36548.1 - 0.0047 16.8 0.3 0.052 13.5 0.1 2.5 3 0 0 3 3 3 1 Kelch motif m04gp34like PF12216.3 ETO36548.1 - 0.028 13.7 0.3 0.051 12.9 0.2 1.4 1 0 0 1 1 1 0 Immune evasion protein WD40 PF00400.27 ETO36550.1 - 9.8e-49 161.5 9.7 6.5e-12 44.8 0.0 5.3 5 1 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO36550.1 - 7.5e-06 24.3 0.8 0.59 8.1 0.0 3.6 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO36550.1 - 0.038 12.7 6.6 0.36 9.5 3.0 2.7 1 1 2 3 3 3 0 Nup133 N terminal like Inhibitor_I9 PF05922.11 ETO36553.1 - 0.13 12.7 0.3 0.27 11.8 0.2 1.7 1 1 0 1 1 1 0 Peptidase inhibitor I9 HTH_Tnp_Tc3_2 PF01498.13 ETO36554.1 - 1.3e-08 34.7 0.1 1.8e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 Transposase Cytomega_US3 PF05963.6 ETO36554.1 - 0.097 12.0 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Cytomegalovirus US3 protein CH PF00307.26 ETO36555.1 - 0.064 13.3 0.7 0.086 12.8 0.5 1.2 1 0 0 1 1 1 0 Calponin homology (CH) domain WD40 PF00400.27 ETO36556.1 - 4.5e-190 609.6 50.6 5.6e-14 51.3 0.2 15.3 15 0 0 15 15 15 15 WD domain, G-beta repeat PQQ_2 PF13360.1 ETO36556.1 - 1.1e-23 83.9 13.5 1e-05 25.1 0.3 6.7 1 1 5 6 6 6 6 PQQ-like domain eIF2A PF08662.6 ETO36556.1 - 9.8e-21 74.3 0.0 0.007 16.0 0.0 6.9 2 2 6 8 8 8 5 Eukaryotic translation initiation factor eIF2A DUF1258 PF06869.7 ETO36556.1 - 6.5e-15 54.9 1.2 0.95 8.4 0.0 9.1 2 2 5 9 9 9 6 Protein of unknown function (DUF1258) Cytochrom_D1 PF02239.11 ETO36556.1 - 3.9e-13 48.4 2.5 0.00058 18.2 0.0 6.0 3 3 4 7 7 7 3 Cytochrome D1 heme domain Gmad1 PF10647.4 ETO36556.1 - 4.8e-09 35.9 11.4 0.23 10.8 0.1 6.4 4 2 1 5 5 5 4 Lipoprotein LpqB beta-propeller domain PQQ_3 PF13570.1 ETO36556.1 - 4.3e-07 29.9 0.5 3.6 7.9 0.0 8.1 8 3 1 9 9 9 1 PQQ-like domain DUF727 PF05303.7 ETO36556.1 - 3.9e-05 23.4 0.1 24 4.7 0.0 8.4 9 4 4 13 13 11 0 Protein of unknown function (DUF727) PQQ PF01011.16 ETO36556.1 - 8.9e-05 21.8 0.2 2.4 7.8 0.0 5.8 8 0 0 8 8 8 1 PQQ enzyme repeat Pentapeptide_4 PF13599.1 ETO36556.1 - 0.00025 20.7 0.2 0.00074 19.2 0.1 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) PD40 PF07676.7 ETO36556.1 - 0.0014 18.2 23.6 24 4.7 0.0 10.4 12 0 0 12 12 12 0 WD40-like Beta Propeller Repeat Pentapeptide PF00805.17 ETO36556.1 - 0.0028 16.8 0.2 0.008 15.3 0.0 1.9 2 0 0 2 2 2 1 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 ETO36556.1 - 0.075 12.9 0.1 0.22 11.4 0.1 1.8 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) USP7_C2 PF14533.1 ETO36556.1 - 0.1 12.0 0.5 1.2e+02 2.0 0.0 5.6 8 0 0 8 8 8 0 Ubiquitin-specific protease C-terminal DUF2335 PF10097.4 ETO36556.1 - 0.16 11.6 0.0 66 3.2 0.0 3.8 4 0 0 4 4 4 0 Predicted membrane protein (DUF2335) Pox_Ag35 PF03286.9 ETO36557.1 - 0.44 10.0 3.9 0.63 9.5 2.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein HEAT PF02985.17 ETO36558.1 - 1.8e-06 27.5 1.6 0.025 14.6 0.0 4.4 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 ETO36558.1 - 3e-06 27.4 0.0 0.00056 20.1 0.0 2.6 3 1 0 3 3 3 1 HEAT repeats ENTH PF01417.15 ETO36558.1 - 0.0026 17.6 5.8 0.34 10.7 0.0 3.9 2 1 1 4 4 4 1 ENTH domain HEAT_EZ PF13513.1 ETO36558.1 - 0.0035 17.7 0.1 0.44 11.1 0.0 3.5 5 0 0 5 5 5 1 HEAT-like repeat Drf_GBD PF06371.8 ETO36558.1 - 0.0041 16.4 2.8 0.0041 16.4 1.9 2.0 1 1 1 2 2 2 1 Diaphanous GTPase-binding Domain Vac14_Fab1_bd PF12755.2 ETO36558.1 - 0.02 15.2 0.5 0.075 13.4 0.1 2.2 2 1 0 2 2 2 0 Vacuolar 14 Fab1-binding region FliS PF02561.9 ETO36558.1 - 0.12 12.2 1.6 0.35 10.7 0.5 2.1 2 1 0 2 2 2 0 Flagellar protein FliS DUF3895 PF13034.1 ETO36559.1 - 0.002 17.5 0.1 0.0033 16.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3895) T2SG PF08334.6 ETO36559.1 - 0.037 13.7 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein G WD40 PF00400.27 ETO36560.1 - 1.9e-81 265.2 32.8 1.3e-13 50.2 0.4 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO36560.1 - 9.3e-11 41.7 3.0 0.00013 21.7 0.0 3.7 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO36560.1 - 8e-06 24.2 15.4 0.89 7.6 0.1 6.3 1 1 5 6 6 6 5 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO36560.1 - 0.0005 18.4 1.4 3.7 5.7 0.0 3.1 1 1 2 3 3 3 3 Cytochrome D1 heme domain Resistin PF06954.6 ETO36560.1 - 0.034 14.4 13.9 12 6.2 0.2 5.9 3 1 4 7 7 7 0 Resistin PD40 PF07676.7 ETO36560.1 - 6.6 6.5 8.4 24 4.7 0.0 4.7 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Exo_endo_phos PF03372.18 ETO36562.1 - 0.0037 17.2 0.0 0.0048 16.8 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 ETO36562.1 - 0.024 14.2 0.2 0.11 12.1 0.2 2.0 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase EMP24_GP25L PF01105.19 ETO36563.1 - 2.2e-27 95.9 0.0 2.9e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4507 PF14964.1 ETO36564.1 - 0.037 12.7 0.1 0.048 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4507) Streptin-Immun PF11083.3 ETO36564.1 - 0.35 10.8 4.6 0.18 11.8 1.7 1.5 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein WD40 PF00400.27 ETO36565.1 - 3.9e-17 61.4 2.3 4.1e-10 39.1 0.0 3.4 3 1 0 3 3 3 3 WD domain, G-beta repeat CDP-OH_P_transf PF01066.16 ETO36566.1 - 1.6e-09 37.9 9.6 1.6e-09 37.9 6.7 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Barstar PF01337.13 ETO36566.1 - 0.13 12.1 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Barstar (barnase inhibitor) RGS PF00615.14 ETO36567.1 - 0.00023 21.2 0.6 0.00023 21.2 0.4 2.1 2 1 0 2 2 2 1 Regulator of G protein signaling domain PAS_10 PF13596.1 ETO36567.1 - 0.0056 16.9 0.2 0.011 15.9 0.2 1.5 1 0 0 1 1 1 1 PAS domain Antimicrobial19 PF08225.6 ETO36567.1 - 0.12 11.7 0.1 0.36 10.2 0.1 1.7 1 0 0 1 1 1 0 Pseudin antimicrobial peptide CoA_binding_3 PF13727.1 ETO36567.1 - 0.18 11.6 0.1 0.18 11.6 0.1 2.5 3 0 0 3 3 3 0 CoA-binding domain zf-H2C2_5 PF13909.1 ETO36567.1 - 1.4 9.2 8.2 3.3 8.1 1.9 3.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Kelch_1 PF01344.20 ETO36570.1 - 4.1e-09 35.8 5.3 5.5e-05 22.6 0.2 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 ETO36570.1 - 1.1e-07 31.7 6.3 0.13 12.5 0.3 4.7 4 1 1 5 5 5 3 Kelch motif Kelch_5 PF13854.1 ETO36570.1 - 0.00012 21.9 3.4 1.8 8.5 0.5 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO36570.1 - 0.001 18.7 2.3 0.59 9.9 0.1 3.7 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO36570.1 - 0.0071 16.0 2.6 0.43 10.4 0.2 3.8 4 0 0 4 4 4 1 Kelch motif 3-HAO PF06052.7 ETO36570.1 - 0.032 13.6 0.0 0.087 12.2 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase TF_AP-2 PF03299.9 ETO36571.1 - 0.084 12.4 0.1 0.11 12.0 0.1 1.1 1 0 0 1 1 1 0 Transcription factor AP-2 Beta_helix PF13229.1 ETO36572.1 - 0.064 13.0 0.0 0.077 12.7 0.0 1.1 1 0 0 1 1 1 0 Right handed beta helix region TPR_12 PF13424.1 ETO36574.1 - 1e-37 127.8 2.6 1e-22 79.8 0.3 3.4 1 1 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO36574.1 - 3.3e-35 119.5 27.3 2.2e-15 56.0 1.3 3.7 1 1 3 4 4 4 4 TPR repeat TPR_1 PF00515.23 ETO36574.1 - 4e-25 86.3 21.5 5.8e-10 38.3 0.6 5.4 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO36574.1 - 4.1e-21 73.1 22.7 3.2e-08 32.7 1.0 5.9 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO36574.1 - 1.6e-20 71.3 12.5 9.4e-07 28.2 0.1 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO36574.1 - 9.6e-20 68.7 7.9 3e-06 26.6 0.0 5.3 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO36574.1 - 1.7e-18 65.8 0.0 1.1e-06 28.3 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO36574.1 - 5.9e-12 45.2 0.5 0.0085 16.4 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO36574.1 - 1.2e-11 43.5 7.8 0.00059 19.0 0.2 4.3 4 0 0 4 4 4 3 SHNi-TPR TPR_17 PF13431.1 ETO36574.1 - 2.4e-09 36.6 9.7 0.0018 18.3 0.1 5.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO36574.1 - 2.8e-08 34.2 0.1 0.00081 19.9 0.0 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat MIT PF04212.13 ETO36574.1 - 5.1e-08 32.6 13.7 0.0015 18.3 0.5 4.7 5 0 0 5 5 4 2 MIT (microtubule interacting and transport) domain TPR_14 PF13428.1 ETO36574.1 - 5.3e-06 26.5 0.0 2.8 8.8 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_3 PF07720.7 ETO36574.1 - 1.6e-05 24.6 13.1 0.00075 19.2 0.3 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat Sel1 PF08238.7 ETO36574.1 - 0.00022 21.7 0.9 0.59 10.8 0.0 3.5 3 0 0 3 3 3 1 Sel1 repeat DUF2225 PF09986.4 ETO36574.1 - 0.00049 19.6 2.7 0.13 11.7 0.2 2.6 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) SPO22 PF08631.5 ETO36574.1 - 0.0036 16.4 0.5 0.41 9.6 0.0 2.4 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like TPR_19 PF14559.1 ETO36574.1 - 0.0092 16.2 0.1 0.22 11.8 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO36574.1 - 0.0097 16.0 10.6 0.015 15.4 1.4 3.2 2 1 1 3 3 2 2 Anaphase-promoting complex, cyclosome, subunit 3 Cas_Cas02710 PF09670.5 ETO36574.1 - 0.015 13.9 0.1 0.036 12.7 0.0 1.7 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) DUF3856 PF12968.2 ETO36574.1 - 0.025 14.4 0.4 4.9 6.9 0.0 3.3 2 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) Bactofilin PF04519.8 ETO36574.1 - 0.057 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Polymer-forming cytoskeletal Ubiq-assoc PF09145.5 ETO36574.1 - 0.09 12.6 4.7 3.8 7.4 0.1 3.6 3 1 0 3 3 3 0 Ubiquitin-associated DUF627 PF04781.7 ETO36574.1 - 0.22 11.1 2.2 9 5.9 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF627) Sec5 PF15469.1 ETO36574.1 - 0.28 10.8 4.1 14 5.3 0.0 3.3 2 1 1 3 3 3 0 Exocyst complex component Sec5 Ribosomal_L18ae PF01775.12 ETO36575.1 - 1e-45 154.6 0.4 1.6e-45 154.0 0.2 1.3 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain NAD_binding_6 PF08030.7 ETO36576.1 - 4.1e-14 52.7 0.0 1.6e-13 50.8 0.0 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 ETO36576.1 - 0.12 12.9 0.3 0.51 10.9 0.1 2.0 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain Ferric_reduct PF01794.14 ETO36577.1 - 6.5e-14 52.0 9.3 1.2e-13 51.1 6.4 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 ETO36577.1 - 1.9e-11 43.7 0.0 3.7e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.19 ETO36577.1 - 0.0001 22.3 0.0 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Tmemb_185A PF10269.4 ETO36577.1 - 0.17 11.4 3.0 0.29 10.7 1.5 1.7 2 0 0 2 2 2 0 Transmembrane Fragile-X-F protein SH3_2 PF07653.12 ETO36578.1 - 1.2e-14 53.4 0.3 3.1e-14 52.1 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 ETO36578.1 - 1.5e-14 53.2 0.7 3.4e-14 52.1 0.5 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 ETO36578.1 - 1.3e-12 46.8 0.7 2.5e-12 45.9 0.5 1.5 1 0 0 1 1 1 1 SH3 domain DUF4345 PF14248.1 ETO36578.1 - 0.088 12.2 4.9 0.039 13.4 1.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4345) CBF PF03914.12 ETO36579.1 - 6.8e-20 71.1 20.1 3.5e-18 65.5 14.0 3.0 1 1 0 1 1 1 1 CBF/Mak21 family DUF2201_N PF13203.1 ETO36579.1 - 5.9 5.9 12.8 11 5.0 8.9 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain Nop14 PF04147.7 ETO36579.1 - 7.3 4.3 33.0 0.1 10.4 18.0 1.4 2 0 0 2 2 2 0 Nop14-like family G-alpha PF00503.15 ETO36580.1 - 3.8e-79 266.1 22.7 7.2e-70 235.6 6.7 2.5 2 1 1 3 3 3 2 G-protein alpha subunit Arf PF00025.16 ETO36580.1 - 1.5e-11 43.8 0.4 6.3e-08 32.0 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 ETO36580.1 - 0.0019 18.6 0.2 2.4 8.7 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 ETO36580.1 - 0.025 14.5 0.0 0.26 11.2 0.0 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 ETO36580.1 - 0.034 13.6 0.0 0.085 12.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.1 ETO36580.1 - 0.072 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain BatD PF13584.1 ETO36580.1 - 0.097 11.2 1.3 0.57 8.7 0.0 2.1 2 0 0 2 2 2 0 Oxygen tolerance ABC_tran PF00005.22 ETO36580.1 - 0.099 12.9 0.1 0.16 12.2 0.1 1.6 1 1 0 1 1 1 0 ABC transporter Gtr1_RagA PF04670.7 ETO36580.1 - 2.4 7.2 13.0 0.087 11.9 0.3 2.8 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region Phage_int_SAM_1 PF02899.12 ETO36581.1 - 0.016 15.3 1.8 0.026 14.6 0.2 2.2 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain RCC1 PF00415.13 ETO36582.1 - 2.2e-34 117.3 6.3 8.4e-13 48.3 0.1 5.5 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETO36582.1 - 2.7e-14 52.3 19.9 4e-06 26.3 0.2 4.6 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat DUF3133 PF11331.3 ETO36582.1 - 0.13 11.7 1.0 9.5 5.8 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3133) Kelch_2 PF07646.10 ETO36583.1 - 2.6e-07 30.1 2.7 0.017 14.8 0.2 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 ETO36583.1 - 5.5e-07 29.4 2.2 7.4 6.9 0.0 5.5 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO36583.1 - 9.2e-06 25.1 9.3 0.004 16.6 0.1 5.2 6 0 0 6 6 6 2 Kelch motif Kelch_4 PF13418.1 ETO36583.1 - 8.4e-05 22.2 0.1 1.4 8.7 0.0 3.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO36583.1 - 0.00033 20.5 0.1 6.6 6.8 0.1 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO36584.1 - 2.5e-08 33.7 2.4 0.0011 19.0 0.1 4.4 3 1 1 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETO36584.1 - 2.8e-08 33.2 2.3 0.0019 17.8 0.1 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO36584.1 - 5.2e-07 29.3 1.1 0.011 15.4 0.1 3.5 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO36584.1 - 4.9e-05 22.7 2.1 0.021 14.3 0.2 3.9 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 ETO36584.1 - 0.013 15.6 0.1 0.096 12.8 0.0 2.5 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO36584.1 - 1.7 8.7 5.0 6.1 6.9 0.1 3.6 4 0 0 4 4 4 0 Kelch motif WD40 PF00400.27 ETO36585.1 - 1.6e-173 557.1 42.3 5.1e-12 45.1 0.0 15.9 15 1 0 15 15 15 15 WD domain, G-beta repeat Nup160 PF11715.3 ETO36585.1 - 1.4e-16 59.8 24.3 0.14 10.2 0.0 12.3 2 2 9 12 12 12 8 Nucleoporin Nup120/160 Str_synth PF03088.11 ETO36585.1 - 1.2e-12 47.7 2.0 0.2 11.7 0.0 8.5 6 3 3 9 9 9 3 Strictosidine synthase PD40 PF07676.7 ETO36585.1 - 7.7e-07 28.6 22.9 0.63 9.7 0.1 10.3 11 0 0 11 11 11 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO36585.1 - 4.8e-06 25.1 7.5 0.19 10.0 0.0 5.8 3 1 4 7 7 7 3 Cytochrome D1 heme domain Pectate_lyase22 PF14583.1 ETO36585.1 - 5.8e-06 25.0 0.0 0.66 8.3 0.0 5.0 2 2 3 5 5 5 2 Oligogalacturonate lyase Pentapeptide PF00805.17 ETO36585.1 - 4.7e-05 22.5 0.1 0.0001 21.4 0.1 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) NYD-SP28_assoc PF14775.1 ETO36585.1 - 0.002 17.8 9.6 53 3.6 0.0 9.8 14 0 0 14 14 14 0 Sperm tail C-terminal domain Pentapeptide_4 PF13599.1 ETO36585.1 - 0.0092 15.7 0.1 0.025 14.3 0.1 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 ETO36585.1 - 0.012 15.4 0.2 0.046 13.6 0.1 2.1 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) Resistin PF06954.6 ETO36585.1 - 0.05 13.8 11.9 46 4.3 0.0 8.4 4 2 5 11 11 11 0 Resistin PLD_C PF12357.3 ETO36585.1 - 0.15 11.5 0.2 1.3e+02 2.1 0.0 5.6 7 2 2 9 9 9 0 Phospholipase D C terminal zf-TRAF PF02176.13 ETO36586.1 - 7.8e-05 22.9 6.2 7.8e-05 22.9 4.3 2.5 2 1 1 3 3 3 1 TRAF-type zinc finger DUF2675 PF11247.3 ETO36586.1 - 0.059 13.4 0.0 0.26 11.3 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2675) 4HB_MCP_1 PF12729.2 ETO36586.1 - 0.12 11.7 5.7 0.2 10.9 3.9 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction DUF342 PF03961.8 ETO36586.1 - 0.23 9.8 2.8 0.46 8.8 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF904 PF06005.7 ETO36586.1 - 2.3 8.5 10.2 1.9 8.8 4.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF904) TSC22 PF01166.13 ETO36586.1 - 3 7.8 9.3 1.3 9.0 2.8 2.7 2 1 0 2 2 2 0 TSC-22/dip/bun family Tup_N PF08581.5 ETO36586.1 - 7.3 6.8 15.2 0.71 10.0 4.2 3.0 2 1 0 2 2 2 0 Tup N-terminal zf-TRAF PF02176.13 ETO36587.1 - 1.5e-06 28.4 5.8 3.1e-06 27.4 4.0 1.6 1 0 0 1 1 1 1 TRAF-type zinc finger Atg14 PF10186.4 ETO36587.1 - 0.0012 17.8 3.8 0.0015 17.5 2.7 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF4435 PF14491.1 ETO36587.1 - 0.0014 18.5 3.0 0.0016 18.2 2.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4435) DUF972 PF06156.8 ETO36587.1 - 0.0071 16.6 7.6 0.018 15.3 5.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF972) Glyco_hydro_26 PF02156.10 ETO36587.1 - 0.022 14.2 0.8 0.032 13.7 0.5 1.2 1 1 0 1 1 1 0 Glycosyl hydrolase family 26 DUF4047 PF13256.1 ETO36587.1 - 0.033 14.1 4.2 0.05 13.5 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) Prenyltransf PF01255.14 ETO36587.1 - 0.035 13.2 1.0 0.055 12.5 0.7 1.3 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase Herpes_BLRF2 PF05812.7 ETO36587.1 - 0.14 11.9 6.7 0.32 10.8 4.6 1.6 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein TSC22 PF01166.13 ETO36587.1 - 0.2 11.6 7.6 2.2 8.3 4.1 2.6 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF342 PF03961.8 ETO36587.1 - 0.41 9.0 5.0 0.53 8.6 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF641 PF04859.7 ETO36587.1 - 0.49 10.1 6.6 1.1 9.0 4.6 1.6 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) U1snRNP70_N PF12220.3 ETO36587.1 - 0.53 10.6 4.9 0.96 9.8 3.4 1.4 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal bZIP_1 PF00170.16 ETO36587.1 - 0.65 9.9 10.8 2.7 8.0 2.5 2.5 1 1 1 2 2 2 0 bZIP transcription factor GP41 PF00517.12 ETO36587.1 - 0.65 9.5 11.3 0.11 12.0 4.6 1.8 1 1 1 2 2 2 0 Retroviral envelope protein RUN PF02759.14 ETO36588.1 - 0.0019 17.9 0.2 0.0048 16.6 0.0 1.8 2 0 0 2 2 2 1 RUN domain TPR_7 PF13176.1 ETO36588.1 - 0.43 10.5 5.0 14 5.7 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETO36588.1 - 0.96 9.5 5.3 12 6.1 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETO36588.1 - 1.1 9.2 5.2 12 5.9 0.2 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETO36588.1 - 1.1 9.1 5.2 2 8.3 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETO36588.1 - 2.6 7.7 9.1 9.2 6.0 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Kelch_6 PF13964.1 ETO36589.1 - 2.8e-07 30.4 2.7 0.074 13.2 0.0 4.6 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.1 ETO36589.1 - 8.6e-07 28.6 0.4 0.0027 17.4 0.0 4.3 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.20 ETO36589.1 - 0.0002 20.8 1.3 0.052 13.1 0.0 3.7 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 ETO36589.1 - 0.00037 20.5 0.0 0.00037 20.5 0.0 4.6 7 0 0 7 7 7 1 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO36589.1 - 0.003 17.2 7.4 0.012 15.3 0.1 4.3 4 1 0 4 4 4 1 Kelch motif Dicty_REP PF05086.7 ETO36589.1 - 0.0075 14.0 0.4 0.0094 13.7 0.3 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein PQQ_3 PF13570.1 ETO36589.1 - 0.076 13.3 0.1 10 6.5 0.0 2.9 3 0 0 3 3 3 0 PQQ-like domain Ank_2 PF12796.2 ETO36591.1 - 0.0051 17.1 0.3 0.021 15.1 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) DUF1514 PF07438.6 ETO36591.1 - 0.048 13.5 0.1 0.048 13.5 0.1 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1514) MipZ PF09140.6 ETO36592.1 - 0.14 11.2 4.4 0.18 10.8 2.6 1.4 1 1 0 1 1 1 0 ATPase MipZ Parvo_coat PF00740.13 ETO36592.1 - 6.2 5.6 20.4 8.2 5.2 14.1 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP2 WD40 PF00400.27 ETO36593.1 - 1.4e-153 493.9 33.2 1e-13 50.5 0.1 14.3 14 0 0 14 14 14 14 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETO36593.1 - 5.2e-14 51.3 3.5 0.016 13.5 0.0 6.6 3 2 5 8 8 8 5 Cytochrome D1 heme domain PD40 PF07676.7 ETO36593.1 - 1.4e-08 34.2 18.9 4.2 7.1 0.0 10.4 11 0 0 11 11 11 2 WD40-like Beta Propeller Repeat Str_synth PF03088.11 ETO36593.1 - 2.4e-08 33.9 0.3 1.8 8.6 0.0 6.9 6 2 1 7 7 7 2 Strictosidine synthase PQQ_2 PF13360.1 ETO36593.1 - 6.5e-08 32.3 4.1 0.0021 17.5 0.5 4.2 2 1 4 6 6 6 5 PQQ-like domain Pentapeptide PF00805.17 ETO36593.1 - 1.5e-06 27.2 0.7 3.4e-06 26.1 0.5 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) DUF1258 PF06869.7 ETO36593.1 - 0.0001 21.4 1.5 0.76 8.8 0.0 5.6 5 1 0 6 6 6 1 Protein of unknown function (DUF1258) Pentapeptide_4 PF13599.1 ETO36593.1 - 0.00031 20.5 0.4 0.00076 19.2 0.2 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 ETO36593.1 - 0.001 18.9 0.7 0.0036 17.1 0.5 2.0 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Resistin PF06954.6 ETO36593.1 - 0.0051 17.0 4.0 44 4.4 0.0 6.3 6 1 1 7 7 7 0 Resistin Proteasome_A_N PF10584.4 ETO36593.1 - 0.0066 15.7 21.7 9.6 5.6 0.0 9.2 9 0 0 9 9 9 1 Proteasome subunit A N-terminal signature Me-amine-dh_H PF06433.6 ETO36593.1 - 0.021 13.4 0.0 2.5 6.6 0.0 3.5 4 1 0 4 4 4 0 Methylamine dehydrogenase heavy chain (MADH) AcetylCoA_hyd_C PF13336.1 ETO36593.1 - 0.029 14.0 0.0 35 4.0 0.0 3.8 2 1 1 3 3 3 0 Acetyl-CoA hydrolase/transferase C-terminal domain NYD-SP28_assoc PF14775.1 ETO36593.1 - 0.039 13.6 9.8 51 3.6 0.0 8.2 10 0 0 10 10 10 0 Sperm tail C-terminal domain GCN5L1 PF06320.8 ETO36594.1 - 0.026 14.3 1.4 0.056 13.2 1.0 1.7 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) Ald_Xan_dh_C PF01315.17 ETO36594.1 - 0.11 12.6 0.2 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Med30 PF11315.3 ETO36594.1 - 1.6 8.8 6.1 0.39 10.8 0.9 2.1 1 1 2 3 3 3 0 Mediator complex subunit 30 Methyltransf_8 PF05148.10 ETO36596.1 - 6e-61 205.8 0.1 1.2e-60 204.9 0.1 1.5 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 ETO36596.1 - 1.3e-08 35.1 0.3 3.9e-06 27.2 0.0 3.1 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_32 PF13679.1 ETO36596.1 - 0.78 9.4 0.0 0.78 9.4 0.0 3.7 2 1 0 2 2 2 0 Methyltransferase domain STAT_bind PF02864.10 ETO36597.1 - 0.14 11.6 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 STAT protein, DNA binding domain Kelch_5 PF13854.1 ETO36598.1 - 0.0019 18.1 0.2 0.083 12.8 0.2 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETO36598.1 - 0.0048 17.0 0.4 1.7 8.9 0.1 2.8 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 ETO36598.1 - 0.0053 16.2 0.3 0.018 14.6 0.1 2.1 2 0 0 2 2 2 1 Kelch motif CobW_C PF07683.9 ETO36598.1 - 0.096 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain zf-C3HC4_3 PF13920.1 ETO36599.1 - 1.9e-13 49.8 9.0 1.9e-13 49.8 6.3 1.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO36599.1 - 2.8e-08 33.6 13.5 5.1e-08 32.8 9.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETO36599.1 - 0.00018 21.1 13.3 0.00018 21.1 9.2 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO36599.1 - 0.0002 20.9 11.3 0.00039 20.1 7.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 ETO36599.1 - 0.00062 19.5 12.3 0.00062 19.5 8.5 1.6 2 0 0 2 2 2 1 Ring finger domain zf-RVT PF13966.1 ETO36599.1 - 0.01 16.1 3.1 2 8.7 0.8 2.3 1 1 1 2 2 2 0 zinc-binding in reverse transcriptase Rad50_zn_hook PF04423.9 ETO36599.1 - 0.096 12.1 0.7 0.096 12.1 0.5 2.3 3 0 0 3 3 3 0 Rad50 zinc hook motif PHF5 PF03660.9 ETO36599.1 - 0.17 11.9 10.6 0.24 11.4 0.1 2.7 1 1 1 2 2 2 0 PHF5-like protein WD40 PF00400.27 ETO36600.1 - 1e-11 44.1 9.2 3.4e-08 33.0 0.5 3.3 2 1 1 3 3 3 2 WD domain, G-beta repeat DUF4154 PF13689.1 ETO36602.1 - 0.043 13.4 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4154) WD40 PF00400.27 ETO36603.1 - 5.3e-20 70.4 8.3 1.5e-09 37.3 0.3 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO36603.1 - 6.5e-05 21.2 4.7 0.0001 20.6 3.3 1.4 1 1 0 1 1 1 1 Nucleoporin Nup120/160 DUF4592 PF15262.1 ETO36603.1 - 0.23 12.0 2.3 0.34 11.4 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4592) Lipoprotein_3 PF00938.12 ETO36603.1 - 0.27 11.0 5.2 0.71 9.6 2.9 2.3 2 1 0 2 2 2 0 Lipoprotein WD40 PF00400.27 ETO36604.1 - 2.4e-26 90.6 1.2 8.6e-11 41.2 0.1 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO36604.1 - 0.00053 18.2 0.2 0.12 10.4 0.1 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 WD40 PF00400.27 ETO36605.1 - 2.6e-16 58.7 2.4 1.1e-09 37.7 0.0 3.2 3 1 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO36605.1 - 0.012 13.7 0.0 0.69 7.9 0.0 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 HAD PF12710.2 ETO36605.1 - 0.024 14.7 0.1 0.034 14.3 0.0 1.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase BBS2_Mid PF14783.1 ETO36605.1 - 0.061 13.1 0.2 1 9.1 0.1 2.4 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 ETO36605.1 - 0.1 11.3 0.5 0.77 8.4 0.1 1.9 1 1 0 2 2 2 0 Nup133 N terminal like DUF3793 PF12672.2 ETO36606.1 - 0.079 12.5 0.1 0.089 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) zf-RING_2 PF13639.1 ETO36606.1 - 1.1 9.1 7.9 2.5 7.9 4.8 2.2 1 1 0 1 1 1 0 Ring finger domain Asparaginase_2 PF01112.13 ETO36609.1 - 2.9e-14 52.5 0.2 1.2e-13 50.4 0.2 1.8 1 1 0 1 1 1 1 Asparaginase CagY_M PF07337.6 ETO36610.1 - 0.0019 17.6 1.3 0.0019 17.6 0.9 2.6 4 0 0 4 4 4 1 DC-EC Repeat DUF3671 PF12420.3 ETO36610.1 - 0.0075 16.2 5.8 0.015 15.2 4.1 1.6 1 1 0 1 1 1 1 Protein of unknown function Sprouty PF05210.8 ETO36610.1 - 0.011 15.6 1.2 0.019 15.0 0.1 1.8 1 1 0 1 1 1 0 Sprouty protein (Spry) Cmc1 PF08583.5 ETO36610.1 - 0.015 15.0 14.3 0.036 13.8 0.3 3.8 3 1 1 4 4 4 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 ETO36610.1 - 0.03 14.2 12.5 0.15 12.0 0.1 3.9 4 0 0 4 4 4 0 CHCH domain DUF979 PF06166.7 ETO36610.1 - 0.034 13.1 0.0 0.039 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF979) DUF4519 PF15012.1 ETO36610.1 - 0.39 10.6 1.9 0.52 10.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) WD40 PF00400.27 ETO36612.1 - 9.9e-26 88.6 18.8 3.9e-13 48.7 0.0 7.0 6 1 1 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 ETO36612.1 - 1.3e-05 23.5 0.1 3.2e-05 22.2 0.1 1.6 1 0 0 1 1 1 1 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO36612.1 - 0.014 15.1 0.1 0.048 13.4 0.0 1.9 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region DUF3601 PF12208.3 ETO36612.1 - 0.038 13.9 0.9 0.15 11.9 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3601) WD40 PF00400.27 ETO36613.1 - 1.6e-23 81.6 8.1 6.5e-08 32.1 0.0 4.2 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO36613.1 - 5e-05 21.6 0.3 0.12 10.4 0.1 2.8 1 1 2 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO36613.1 - 0.0062 16.2 0.3 0.24 11.1 0.1 2.3 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 ETO36613.1 - 0.1 11.2 3.9 0.43 9.2 2.7 2.0 1 1 0 1 1 1 0 Nup133 N terminal like CHIPS PF11434.3 ETO36614.1 - 0.59 9.7 4.0 1.2 8.8 2.8 1.6 1 1 0 1 1 1 0 Chemotaxis-inhibiting protein CHIPS AIG1 PF04548.11 ETO36616.1 - 2.3e-06 26.8 0.0 2.3e-06 26.8 0.0 2.7 2 1 1 3 3 3 1 AIG1 family DinI PF06183.8 ETO36616.1 - 1.2 9.2 5.6 0.25 11.4 0.7 2.3 2 0 0 2 2 2 0 DinI-like family AHSP PF09236.5 ETO36616.1 - 1.4 9.1 13.5 0.086 13.0 1.3 3.3 3 1 0 3 3 3 0 Alpha-haemoglobin stabilising protein Ribonuc_red_lgC PF02867.10 ETO36618.1 - 2e-06 26.6 0.0 0.00085 18.0 0.0 2.6 2 1 0 3 3 3 2 Ribonucleotide reductase, barrel domain WD40 PF00400.27 ETO36619.1 - 0.00029 20.5 0.1 0.37 10.7 0.1 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat CTDII PF01556.13 ETO36621.1 - 2.3e-19 69.0 7.8 4.6e-09 36.0 0.0 3.8 4 0 0 4 4 4 3 DnaJ C terminal domain PA14_2 PF10528.4 ETO36621.1 - 0.29 11.1 2.1 0.56 10.1 1.5 1.4 1 0 0 1 1 1 0 GLEYA domain Fork_head_N PF08430.7 ETO36621.1 - 1.4 9.3 19.9 2.1 8.7 13.8 1.2 1 0 0 1 1 1 0 Forkhead N-terminal region ADK PF00406.17 ETO36622.1 - 4.4e-08 33.1 0.3 5e-08 32.9 0.2 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK PF00406.17 ETO36623.1 - 8.5e-31 106.8 0.0 1.1e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 ETO36623.1 - 3.5e-08 34.3 0.0 4.9e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 ETO36623.1 - 2.3e-06 26.8 0.0 4.2e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 ETO36623.1 - 3.7e-05 24.0 0.1 5.2e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETO36623.1 - 0.00029 20.7 0.0 0.00038 20.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 ETO36623.1 - 0.035 12.9 0.1 0.035 12.9 0.0 1.3 1 1 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.1 ETO36623.1 - 0.079 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Thymidylate_kin PF02223.12 ETO36623.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.4 1 1 0 1 1 1 0 Thymidylate kinase Viral_helicase1 PF01443.13 ETO36623.1 - 0.11 12.0 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TPR_11 PF13414.1 ETO36624.1 - 2.2e-19 68.8 6.1 1.9e-10 40.2 0.5 5.2 4 2 2 6 6 6 2 TPR repeat TPR_19 PF14559.1 ETO36624.1 - 2.3e-17 63.0 8.7 1.6e-06 28.3 0.1 5.1 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO36624.1 - 3e-17 61.3 2.8 6.1e-05 22.9 0.0 6.9 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO36624.1 - 6.8e-15 53.6 4.0 0.0019 17.8 0.0 6.2 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETO36624.1 - 2.4e-14 53.5 3.6 2.5e-08 34.3 0.1 4.6 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETO36624.1 - 6.7e-14 51.1 0.8 0.0018 18.7 0.1 6.8 3 1 4 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO36624.1 - 3.7e-12 45.1 9.4 0.0022 17.7 0.0 6.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO36624.1 - 3.5e-11 42.2 11.4 0.0002 20.8 0.0 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 ETO36624.1 - 1.3e-09 37.7 1.6 5.8e-06 26.1 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 ETO36624.1 - 5e-07 29.7 0.6 3.7e-06 26.9 0.1 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 ETO36624.1 - 1.2e-06 28.4 6.1 0.024 14.7 0.1 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETO36624.1 - 0.00044 20.0 0.0 0.0016 18.2 0.0 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_21 PF09976.4 ETO36624.1 - 0.0012 18.8 1.4 0.0027 17.6 0.3 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO36624.1 - 0.0015 18.8 2.6 4.1 8.0 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 ETO36624.1 - 0.0045 16.0 1.0 4 6.4 0.1 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETO36624.1 - 0.0092 15.8 1.2 8.5 6.3 0.0 4.2 4 1 1 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.5 ETO36624.1 - 0.061 12.0 0.1 0.15 10.8 0.0 1.6 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_4 PF07721.9 ETO36624.1 - 0.069 13.6 0.0 1.1 9.9 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_M13_N PF05649.8 ETO36625.1 - 2.2e-09 36.8 0.0 3e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 WD40 PF00400.27 ETO36626.1 - 5.4e-51 168.7 6.8 1.1e-09 37.8 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO36626.1 - 4.2e-08 31.7 0.3 0.0088 14.2 0.1 3.8 2 2 1 4 4 4 3 Nucleoporin Nup120/160 DPPIV_N PF00930.16 ETO36626.1 - 8.4e-07 27.8 0.3 0.00024 19.8 0.1 3.6 3 1 1 4 4 4 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.7 ETO36626.1 - 1.7e-05 24.3 6.1 2.8 7.6 0.0 6.1 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat Kelch_6 PF13964.1 ETO36626.1 - 0.0001 22.2 8.3 0.00061 19.8 0.1 4.5 4 1 1 5 5 5 1 Kelch motif Kelch_4 PF13418.1 ETO36626.1 - 0.0052 16.5 0.0 6.2 6.6 0.0 3.9 4 0 0 4 4 4 1 Galactose oxidase, central domain BRX PF08381.6 ETO36626.1 - 0.023 13.7 0.0 5 6.2 0.0 2.7 2 0 0 2 2 2 0 Transcription factor regulating root and shoot growth via Pin3 DUF1506 PF07405.6 ETO36626.1 - 0.13 12.2 3.5 11 5.9 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1506) TPT PF03151.11 ETO36627.1 - 2e-12 47.0 16.4 3.7e-12 46.1 11.4 1.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family Peptidase_M56 PF05569.6 ETO36627.1 - 0.063 12.2 3.6 0.062 12.2 1.7 1.6 1 1 1 2 2 2 0 BlaR1 peptidase M56 TIP49 PF06068.8 ETO36628.1 - 1.9e-28 99.3 1.4 2.1e-28 99.1 1.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 ETO36628.1 - 1.3e-05 24.3 0.1 1.7e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 ETO36628.1 - 0.0087 15.7 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 ETO36628.1 - 0.0094 15.1 0.2 0.013 14.7 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 ETO36628.1 - 0.013 14.8 0.2 0.02 14.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 ETO36628.1 - 0.019 15.1 0.2 0.03 14.5 0.1 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETO36628.1 - 0.027 14.4 0.0 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.4 ETO36628.1 - 0.036 13.0 0.1 0.22 10.4 0.2 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 ETO36628.1 - 0.039 13.1 0.3 0.061 12.5 0.2 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF258 PF03193.11 ETO36628.1 - 0.042 13.0 0.5 0.057 12.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Parvo_NS1 PF01057.12 ETO36628.1 - 0.044 12.6 0.3 0.09 11.6 0.1 1.4 1 1 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.7 ETO36628.1 - 0.048 12.7 0.1 0.067 12.2 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.9 ETO36628.1 - 0.066 12.9 0.1 0.095 12.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) G-patch PF01585.18 ETO36628.1 - 0.09 12.5 0.2 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 G-patch domain GvpD PF07088.6 ETO36628.1 - 0.11 10.7 0.1 0.16 10.2 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein DDRGK PF09756.4 ETO36629.1 - 2.2 7.6 16.2 0.35 10.2 8.4 1.7 2 0 0 2 2 2 0 DDRGK domain DUF607 PF04678.8 ETO36629.1 - 2.9 7.7 7.2 13 5.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF607 WD40 PF00400.27 ETO36630.1 - 2.4e-71 233.2 12.3 8.9e-14 50.7 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO36630.1 - 3.1e-13 49.8 0.2 3.7e-06 26.7 0.0 3.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO36630.1 - 6.8e-10 37.6 1.9 0.0058 14.8 0.1 4.4 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Nbas_N PF15492.1 ETO36630.1 - 3.4e-05 23.1 3.1 1.1 8.3 0.0 3.7 1 1 2 3 3 3 3 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 ETO36630.1 - 4.5e-05 23.0 0.2 0.00063 19.2 0.1 3.0 1 1 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 ETO36630.1 - 0.00027 19.3 0.4 0.38 8.9 0.0 3.3 2 2 1 3 3 3 1 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 ETO36630.1 - 0.0077 15.5 3.8 20 4.6 0.0 4.8 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature PD40 PF07676.7 ETO36630.1 - 0.0081 15.8 7.2 23 4.7 0.0 5.0 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Alpha-L-AF_C PF06964.7 ETO36630.1 - 0.039 13.7 0.1 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 Alpha-L-arabinofuranosidase C-terminus DUF1513 PF07433.6 ETO36630.1 - 0.041 12.7 0.1 4.7 6.0 0.0 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1513) DUF91 PF01939.11 ETO36630.1 - 0.063 12.4 0.1 0.16 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF91 WD40 PF00400.27 ETO36631.1 - 1.6e-38 129.2 9.9 2e-14 52.8 0.1 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 ETO36631.1 - 2.5e-09 37.1 2.0 0.00088 19.0 0.1 2.6 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETO36631.1 - 8.7e-06 25.2 5.3 2 8.1 0.1 5.0 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 ETO36631.1 - 9.4e-06 24.1 0.2 6.1e-05 21.4 0.0 2.2 1 1 1 2 2 2 1 Cytochrome D1 heme domain Nup160 PF11715.3 ETO36631.1 - 4.9e-05 21.6 0.7 0.02 13.0 0.1 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Str_synth PF03088.11 ETO36631.1 - 0.0015 18.4 0.1 0.3 11.1 0.0 3.5 3 2 1 4 4 4 1 Strictosidine synthase Nucleoporin_N PF08801.6 ETO36631.1 - 0.012 14.3 0.6 0.39 9.4 0.4 2.2 1 1 0 1 1 1 0 Nup133 N terminal like SGL PF08450.7 ETO36631.1 - 0.016 14.5 0.0 1.3 8.3 0.0 2.2 1 1 1 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region PQQ_2 PF13360.1 ETO36631.1 - 0.029 13.8 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 PQQ-like domain Nbas_N PF15492.1 ETO36631.1 - 0.062 12.4 0.5 17 4.3 0.0 3.1 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Coatomer_WDAD PF04053.9 ETO36631.1 - 0.068 11.9 0.4 0.15 10.8 0.3 1.6 1 1 0 1 1 1 0 Coatomer WD associated region HCR PF07111.7 ETO36632.1 - 0.0068 14.4 0.3 0.011 13.8 0.2 1.3 1 0 0 1 1 1 1 Alpha helical coiled-coil rod protein (HCR) DUF972 PF06156.8 ETO36632.1 - 2.2 8.6 7.0 1.9 8.8 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF972) 2TM PF13239.1 ETO36634.1 - 0.22 11.5 2.4 9.1 6.4 0.1 2.5 2 0 0 2 2 2 0 2TM domain WD40 PF00400.27 ETO36636.1 - 2.5e-12 46.1 0.0 9.7e-11 41.1 0.0 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat Crust_neuro_H PF03858.8 ETO36636.1 - 0.048 14.2 0.0 0.42 11.2 0.0 2.0 2 0 0 2 2 2 0 Crustacean neurohormone H EF-hand_1 PF00036.27 ETO36637.1 - 3.4e-05 22.8 0.6 0.0017 17.4 0.2 2.9 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 ETO36637.1 - 0.00032 20.7 0.5 0.00096 19.2 0.4 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 ETO36637.1 - 0.0005 19.3 0.4 0.0015 17.7 0.3 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 ETO36637.1 - 0.0023 17.6 0.5 0.15 12.0 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 ETO36637.1 - 0.0035 16.9 1.2 0.0078 15.8 0.8 1.7 1 0 0 1 1 1 1 EF-hand domain pair Rotavirus_VP7 PF05868.6 ETO36637.1 - 0.02 14.0 0.3 0.03 13.4 0.2 1.2 1 0 0 1 1 1 0 Rotavirus major outer capsid protein VP7 DUF3584 PF12128.3 ETO36638.1 - 0.16 9.2 25.2 0.2 8.9 17.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2775 PF10950.3 ETO36638.1 - 0.67 10.2 10.1 1.2 9.3 6.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2775) Baculo_PEP_C PF04513.7 ETO36638.1 - 1.3 8.8 5.7 4.9 6.9 0.2 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAGA_bind PF06217.7 ETO36638.1 - 2.8 7.8 10.0 3.4 7.5 6.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family UPF0061 PF02696.9 ETO36638.1 - 3.1 5.9 8.2 12 4.0 5.6 1.8 1 1 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family DUF342 PF03961.8 ETO36638.1 - 3.3 6.0 22.8 0.37 9.1 10.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) TPR_MLP1_2 PF07926.7 ETO36638.1 - 7.4 6.3 33.9 32 4.2 0.1 3.1 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein GBP_C PF02841.9 ETO36638.1 - 9.2 5.3 26.8 13 4.8 18.6 1.4 1 1 0 1 1 1 0 Guanylate-binding protein, C-terminal domain WD40 PF00400.27 ETO36639.1 - 9.9e-40 133.0 3.0 9e-13 47.5 0.0 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO36639.1 - 1.2e-05 23.6 0.1 0.039 12.1 0.0 2.6 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 ETO36639.1 - 0.075 12.7 0.1 3.7 7.1 0.0 2.4 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A XK-related PF09815.4 ETO36641.1 - 0.0032 16.5 7.3 0.0032 16.5 4.0 1.8 2 1 0 2 2 2 1 XK-related protein ABC2_membrane_3 PF12698.2 ETO36641.1 - 0.64 8.9 6.5 0.82 8.6 4.5 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2469 PF10611.4 ETO36642.1 - 0.044 14.1 0.0 0.075 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2469) Cupin_8 PF13621.1 ETO36643.1 - 2.1e-11 43.8 12.5 1.4e-10 41.0 8.7 2.1 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 ETO36643.1 - 0.0021 17.3 1.0 0.015 14.5 0.2 2.6 2 1 0 3 3 3 1 Cupin superfamily protein Cupin_2 PF07883.6 ETO36643.1 - 0.0052 16.2 0.1 2.4 7.7 0.0 2.5 2 0 0 2 2 2 2 Cupin domain Pkinase PF00069.20 ETO36644.1 - 1.3e-43 149.0 0.7 1.1e-35 123.0 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO36644.1 - 1.9e-20 73.0 0.0 2.3e-15 56.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Myosin_TH1 PF06017.8 ETO36644.1 - 6.8e-16 58.1 0.6 1.2e-15 57.3 0.4 1.3 1 0 0 1 1 1 1 Myosin tail Pkinase_C PF00433.19 ETO36644.1 - 2.8e-06 27.7 2.6 6.7e-06 26.5 1.8 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 ETO36644.1 - 0.026 13.5 0.0 0.047 12.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF4484 PF14831.1 ETO36645.1 - 0.036 14.1 0.7 0.049 13.7 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4484) DASH_Spc34 PF08657.5 ETO36645.1 - 1.6 8.3 13.2 0.16 11.5 4.3 1.9 1 1 1 2 2 2 0 DASH complex subunit Spc34 Pro_dh PF01619.13 ETO36646.1 - 2.5e-50 171.2 1.0 4e-50 170.5 0.7 1.3 1 1 0 1 1 1 1 Proline dehydrogenase bZIP_1 PF00170.16 ETO36648.1 - 0.049 13.5 1.5 0.12 12.3 1.1 1.7 1 0 0 1 1 1 0 bZIP transcription factor Rootletin PF15035.1 ETO36648.1 - 0.35 10.8 9.5 0.087 12.7 2.9 2.1 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF972 PF06156.8 ETO36648.1 - 2.5 8.4 7.3 1.7 9.0 2.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) PTRF_SDPR PF15237.1 ETO36650.1 - 0.14 11.5 7.5 0.15 11.3 5.2 1.1 1 0 0 1 1 1 0 PTRF/SDPR family RR_TM4-6 PF06459.7 ETO36650.1 - 6.7 6.5 9.1 9.2 6.0 6.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3785 PF12653.2 ETO36651.1 - 0.031 14.1 0.2 0.083 12.7 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3785) DUF2746 PF10874.3 ETO36651.1 - 0.075 13.2 1.2 13 6.0 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2746) DUF4200 PF13863.1 ETO36651.1 - 0.69 9.8 13.8 0.34 10.8 0.8 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) DUF4618 PF15397.1 ETO36651.1 - 6.1 6.1 16.6 0.31 10.3 1.1 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4618) DUF4275 PF14101.1 ETO36652.1 - 0.035 14.1 2.2 0.053 13.5 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4275) DUF1767 PF08585.7 ETO36652.1 - 0.31 11.3 2.3 13 6.1 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1767) MatE PF01554.13 ETO36653.1 - 0.91 9.1 15.5 2.3 7.8 1.8 2.7 2 1 0 2 2 2 0 MatE CTDII PF01556.13 ETO36655.1 - 3.3e-10 39.7 0.0 5.5e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain EF-hand_6 PF13405.1 ETO36656.1 - 1.9e-12 45.9 2.1 0.00098 18.8 0.1 3.9 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.1 ETO36656.1 - 2.3e-11 43.6 3.3 3.8e-08 33.3 0.4 2.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 ETO36656.1 - 1.4e-10 39.6 4.6 0.00044 19.3 0.0 3.9 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 ETO36656.1 - 1.3e-07 31.1 1.2 6.7e-05 22.4 0.1 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 ETO36656.1 - 6e-07 28.5 5.0 0.0013 17.9 0.0 3.7 3 0 0 3 3 3 2 EF hand DUF937 PF06078.6 ETO36656.1 - 0.0039 17.4 0.0 0.007 16.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF937) Ion_trans PF00520.26 ETO36657.1 - 0.0064 15.7 1.1 0.011 15.0 0.8 1.3 1 0 0 1 1 1 1 Ion transport protein WWE PF02825.15 ETO36657.1 - 0.023 14.0 0.8 0.23 10.8 0.6 2.5 1 1 0 1 1 1 0 WWE domain 7tm_1 PF00001.16 ETO36657.1 - 0.039 13.0 0.2 0.065 12.3 0.1 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) GWT1 PF06423.7 ETO36657.1 - 0.093 12.8 2.8 0.86 9.6 1.9 2.4 1 1 0 1 1 1 0 GWT1 RDD PF06271.7 ETO36657.1 - 0.12 12.2 3.1 0.088 12.6 0.7 1.8 2 0 0 2 2 2 0 RDD family DUF4234 PF14018.1 ETO36657.1 - 0.46 10.2 2.5 0.86 9.3 0.4 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4234) PARP PF00644.15 ETO36658.1 - 3e-09 36.6 0.0 5.3e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Molybdopterin PF00384.17 ETO36658.1 - 0.049 12.3 0.0 0.05 12.3 0.0 1.1 1 0 0 1 1 1 0 Molybdopterin oxidoreductase Pkinase PF00069.20 ETO36659.1 - 1.2e-72 244.2 0.0 2.3e-72 243.2 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO36659.1 - 1.2e-30 106.5 0.0 4.1e-30 104.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO36659.1 - 9.8e-05 21.4 0.0 0.00018 20.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETO36659.1 - 0.0012 18.6 0.1 0.032 13.9 0.0 2.4 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 ETO36659.1 - 0.0016 17.5 0.0 0.003 16.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 ETO36659.1 - 0.066 12.5 2.3 0.16 11.2 0.1 2.5 2 1 0 2 2 2 0 PhoP regulatory network protein YrbL CCDC-167 PF15188.1 ETO36659.1 - 0.54 10.2 3.6 7.1 6.6 0.1 2.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 XRN_N PF03159.13 ETO36661.1 - 1.1e-27 96.9 4.6 1e-18 67.6 0.0 3.1 1 1 2 3 3 3 3 XRN 5'-3' exonuclease N-terminus DUF4615 PF15393.1 ETO36662.1 - 0.061 13.5 0.4 0.095 12.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) Mut7-C PF01927.11 ETO36663.1 - 3.4e-11 43.3 0.0 0.00021 21.2 0.0 3.1 3 0 0 3 3 3 2 Mut7-C RNAse domain Exo_endo_phos PF03372.18 ETO36663.1 - 0.0046 16.9 0.2 0.019 14.9 0.0 1.9 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Snf7 PF03357.16 ETO36664.1 - 1.7e-19 69.8 12.1 1.7e-19 69.8 8.4 2.7 2 1 1 3 3 3 1 Snf7 DivIC PF04977.10 ETO36664.1 - 0.00039 19.8 10.2 0.15 11.5 0.5 3.9 3 1 0 3 3 3 2 Septum formation initiator UPF0184 PF03670.8 ETO36664.1 - 0.0068 16.5 4.0 0.9 9.7 0.0 3.3 4 0 0 4 4 4 2 Uncharacterised protein family (UPF0184) DisA-linker PF10635.4 ETO36664.1 - 0.038 13.4 3.6 2.2 7.7 0.1 2.6 3 0 0 3 3 3 0 DisA bacterial checkpoint controller linker region Pox_E10 PF04805.7 ETO36664.1 - 0.048 13.2 0.9 3.1 7.3 0.1 2.6 2 0 0 2 2 2 0 E10-like protein conserved region Virulence_fact PF13769.1 ETO36664.1 - 0.084 12.7 0.5 0.084 12.7 0.3 2.2 2 1 1 3 3 3 0 Virulence factor Myotub-related PF06602.9 ETO36664.1 - 0.15 10.7 1.3 0.23 10.2 0.9 1.3 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain V_ATPase_I PF01496.14 ETO36664.1 - 0.25 9.1 6.9 0.35 8.6 4.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 ETO36664.1 - 3.5 7.1 16.0 1e+02 2.3 10.4 2.9 2 1 0 2 2 2 0 IncA protein PCI_Csn8 PF10075.4 ETO36665.1 - 0.17 11.6 2.8 0.86 9.3 0.5 2.2 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 SAE2 PF08573.5 ETO36666.1 - 0.85 10.3 12.9 0.1 13.3 5.2 2.1 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus DUF3546 PF12066.3 ETO36667.1 - 0.0097 15.9 3.2 0.014 15.3 2.2 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3546) EutC PF05985.6 ETO36667.1 - 0.062 12.3 0.4 1.2 8.1 0.0 2.1 1 1 1 2 2 2 0 Ethanolamine ammonia-lyase light chain (EutC) DUF2691 PF10903.3 ETO36667.1 - 0.12 12.2 1.0 1.1 9.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2691) Ycf4 PF02392.11 ETO36668.1 - 0.025 13.8 0.4 0.033 13.5 0.3 1.3 1 1 0 1 1 1 0 Ycf4 Endonuc-BsobI PF09194.5 ETO36668.1 - 0.11 11.4 0.4 0.12 11.2 0.3 1.1 1 0 0 1 1 1 0 Restriction endonuclease BsobI DUF3987 PF13148.1 ETO36668.1 - 4 5.8 6.1 7.9 4.9 4.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3987) zf-CCHC PF00098.18 ETO36669.1 - 0.28 11.1 4.6 0.54 10.2 3.2 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 ETO36669.1 - 0.29 10.6 9.1 0.62 9.5 6.3 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Exo_endo_phos_2 PF14529.1 ETO36671.1 - 3.1e-10 39.7 0.1 5.5e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase HisG_C PF08029.6 ETO36672.1 - 0.023 14.6 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 HisG, C-terminal domain WD40 PF00400.27 ETO36673.1 - 2.2e-155 499.7 39.2 4.5e-11 42.1 0.4 16.2 16 0 0 16 16 16 16 WD domain, G-beta repeat PQQ_2 PF13360.1 ETO36673.1 - 2.2e-06 27.3 3.2 0.61 9.5 0.0 4.5 1 1 1 3 3 3 3 PQQ-like domain DUF1258 PF06869.7 ETO36673.1 - 1e-05 24.8 1.2 2.4 7.1 0.0 6.2 4 2 4 8 8 8 1 Protein of unknown function (DUF1258) PD40 PF07676.7 ETO36673.1 - 2.5e-05 23.8 34.1 0.32 10.7 0.0 11.9 13 0 0 13 13 13 1 WD40-like Beta Propeller Repeat Pentapeptide PF00805.17 ETO36673.1 - 5.4e-05 22.3 3.3 0.00033 19.8 1.6 2.1 1 1 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO36673.1 - 0.00015 21.4 1.6 0.00048 19.8 1.1 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 ETO36673.1 - 0.00037 20.3 13.0 0.0031 17.3 2.5 2.2 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Mid2 PF04478.7 ETO36673.1 - 0.018 14.4 13.9 4.2 6.7 0.1 7.1 5 3 3 9 9 9 0 Mid2 like cell wall stress sensor Resistin PF06954.6 ETO36673.1 - 0.044 14.0 0.0 30 4.9 0.0 4.6 4 1 1 5 5 5 0 Resistin DUF3732 PF12532.3 ETO36673.1 - 0.12 11.8 1.1 3.9 6.9 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3732) CsgF PF10614.4 ETO36673.1 - 0.13 12.2 1.1 33 4.4 0.0 4.1 3 1 1 4 4 4 0 Type VIII secretion system (T8SS), CsgF protein Peptidase_C69 PF03577.10 ETO36673.1 - 0.14 10.9 6.3 30 3.3 0.1 5.8 5 2 2 7 7 7 0 Peptidase family C69 LAGLIDADG_3 PF14528.1 ETO36673.1 - 0.16 12.1 1.5 37 4.6 0.0 4.5 5 0 0 5 5 5 0 LAGLIDADG-like domain Cytochrom_D1 PF02239.11 ETO36673.1 - 0.28 9.4 13.2 20 3.3 0.1 6.3 2 2 4 7 7 7 0 Cytochrome D1 heme domain UN_NPL4 PF11543.3 ETO36673.1 - 0.44 10.8 7.3 61 3.9 0.0 7.2 10 1 1 11 11 11 0 Nuclear pore localisation protein NPL4 NPV_P10 PF05531.7 ETO36676.1 - 0.00022 21.4 3.0 0.00022 21.4 2.1 2.4 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein PhaP_Bmeg PF09602.5 ETO36676.1 - 0.08 12.7 13.5 0.034 13.9 6.6 2.1 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) HAUS-augmin3 PF14932.1 ETO36676.1 - 0.23 10.5 20.9 0.18 10.9 10.7 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Prefoldin_2 PF01920.15 ETO36676.1 - 1 9.1 30.0 0.65 9.7 6.0 3.3 3 0 0 3 3 3 0 Prefoldin subunit LAGLIDADG_1 PF00961.14 ETO36676.1 - 1.7 9.2 17.3 0.18 12.3 4.0 2.7 3 0 0 3 3 3 0 LAGLIDADG endonuclease Phage_GPO PF05929.6 ETO36676.1 - 2.2 7.4 10.9 0.26 10.4 4.2 1.8 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase ApoL PF05461.6 ETO36676.1 - 2.5 7.2 13.3 0.76 8.9 6.1 2.1 2 0 0 2 2 2 0 Apolipoprotein L CorA PF01544.13 ETO36676.1 - 2.8 6.9 9.8 4 6.3 2.2 2.4 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Cor1 PF04803.7 ETO36676.1 - 3.2 7.5 26.4 12 5.7 14.6 3.1 2 1 0 2 2 2 0 Cor1/Xlr/Xmr conserved region Tweety PF04906.8 ETO36676.1 - 4.2 5.6 7.1 3.2 6.0 2.0 1.8 1 1 1 2 2 2 0 Tweety SDH_alpha PF03313.10 ETO36676.1 - 4.7 6.1 6.1 8.2 5.3 4.2 1.3 1 0 0 1 1 1 0 Serine dehydratase alpha chain OmpH PF03938.9 ETO36676.1 - 4.9 7.0 23.1 1.4 8.8 0.6 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Fib_alpha PF08702.5 ETO36676.1 - 5.5 7.1 21.1 2.7 8.0 10.9 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ATP-synt_B PF00430.13 ETO36676.1 - 6.2 6.6 20.2 6.2 6.6 11.6 2.3 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) BLOC1_2 PF10046.4 ETO36677.1 - 0.00063 19.8 0.9 0.00072 19.6 0.4 1.3 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.10 ETO36677.1 - 0.0066 15.9 2.7 0.0093 15.4 1.8 1.5 1 1 0 1 1 1 1 Septum formation initiator Img2 PF05046.9 ETO36677.1 - 0.013 15.6 0.3 0.015 15.5 0.2 1.1 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) DUF4200 PF13863.1 ETO36677.1 - 0.018 14.9 0.2 0.018 14.9 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF1664 PF07889.7 ETO36677.1 - 0.021 14.6 1.1 0.026 14.2 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Phlebovirus_NSM PF07246.6 ETO36677.1 - 0.027 13.6 0.4 0.032 13.3 0.2 1.2 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M FliD_N PF02465.13 ETO36677.1 - 0.027 14.8 1.5 0.029 14.7 1.1 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus DivIVA PF05103.8 ETO36677.1 - 0.029 14.4 3.3 0.034 14.2 2.3 1.2 1 0 0 1 1 1 0 DivIVA protein EF_TS PF00889.14 ETO36677.1 - 0.03 13.6 0.2 0.031 13.6 0.1 1.1 1 0 0 1 1 1 0 Elongation factor TS LPP PF04728.8 ETO36677.1 - 0.035 13.9 0.7 0.048 13.4 0.5 1.4 1 0 0 1 1 1 0 Lipoprotein leucine-zipper bZIP_2 PF07716.10 ETO36677.1 - 0.035 13.9 1.1 0.035 13.9 0.8 1.5 2 0 0 2 2 2 0 Basic region leucine zipper AKNA PF12443.3 ETO36677.1 - 0.038 13.9 1.6 0.048 13.6 1.1 1.1 1 0 0 1 1 1 0 AT-hook-containing transcription factor DUF4407 PF14362.1 ETO36677.1 - 0.041 12.8 1.4 0.039 12.8 1.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ax_dynein_light PF10211.4 ETO36677.1 - 0.043 13.6 2.2 0.052 13.3 1.5 1.0 1 0 0 1 1 1 0 Axonemal dynein light chain Seryl_tRNA_N PF02403.17 ETO36677.1 - 0.058 13.4 1.4 0.069 13.1 0.4 1.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF2730 PF10805.3 ETO36677.1 - 0.061 13.0 0.2 0.065 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) H-kinase_dim PF02895.9 ETO36677.1 - 0.08 13.2 0.7 0.13 12.6 0.5 1.3 1 0 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain Atg14 PF10186.4 ETO36677.1 - 0.091 11.6 3.0 0.1 11.5 2.1 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_DNA_bd PF12329.3 ETO36677.1 - 0.1 12.3 2.6 0.23 11.2 1.7 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 ETO36677.1 - 0.12 11.5 0.3 0.12 11.5 0.2 1.0 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Sec2p PF06428.6 ETO36677.1 - 0.12 12.2 2.1 0.14 12.0 1.5 1.2 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Spc42p PF11544.3 ETO36677.1 - 0.19 11.6 2.8 0.34 10.8 1.9 1.5 1 1 0 1 1 1 0 Spindle pole body component Spc42p DUF3573 PF12097.3 ETO36677.1 - 0.27 9.7 2.9 0.26 9.8 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) FlxA PF14282.1 ETO36677.1 - 0.51 10.3 9.4 1.3 9.0 6.5 1.7 1 1 0 1 1 1 0 FlxA-like protein ABC_membrane_2 PF06472.10 ETO36679.1 - 1.1e-06 27.9 0.1 1.5e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 BUD22 PF09073.5 ETO36679.1 - 0.0026 16.9 21.9 0.0035 16.4 15.1 1.1 1 0 0 1 1 1 1 BUD22 BSP_II PF05432.6 ETO36679.1 - 0.021 14.1 24.7 0.034 13.4 17.1 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) IncA PF04156.9 ETO36679.1 - 0.71 9.4 19.8 1.2 8.7 13.7 1.4 1 0 0 1 1 1 0 IncA protein Ycf1 PF05758.7 ETO36679.1 - 0.81 7.3 17.1 0.95 7.0 11.9 1.1 1 0 0 1 1 1 0 Ycf1 Nop14 PF04147.7 ETO36679.1 - 0.93 7.3 30.3 1.2 6.9 21.0 1.3 1 0 0 1 1 1 0 Nop14-like family Caldesmon PF02029.10 ETO36679.1 - 1.5 7.1 33.1 2.1 6.6 23.0 1.1 1 0 0 1 1 1 0 Caldesmon Miro PF08477.8 ETO36679.1 - 1.8 9.0 5.1 3.5 8.1 2.6 2.0 1 1 0 1 1 1 0 Miro-like protein DUF572 PF04502.8 ETO36679.1 - 2.4 7.3 29.4 3.1 6.9 20.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Herpes_DNAp_acc PF04929.7 ETO36679.1 - 8.1 5.2 12.4 11 4.8 8.6 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor ABC_tran PF00005.22 ETO36680.1 - 1.5e-18 67.4 0.0 3e-18 66.4 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 ETO36680.1 - 3.3e-08 33.8 0.2 2.7e-05 24.2 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_29 PF13555.1 ETO36680.1 - 0.00011 21.6 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 ETO36680.1 - 0.00089 19.6 0.2 0.0019 18.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 ETO36680.1 - 0.00091 18.5 0.1 0.0037 16.5 0.1 1.8 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 ETO36680.1 - 0.022 13.8 0.1 0.033 13.2 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 ETO36680.1 - 0.022 14.2 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.1 ETO36680.1 - 0.063 13.2 0.1 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.1 ETO36680.1 - 0.069 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 ETO36680.1 - 0.12 13.2 0.1 0.21 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 ETO36680.1 - 0.13 12.2 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF815 PF05673.8 ETO36680.1 - 0.14 11.0 0.1 0.23 10.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PHD_2 PF13831.1 ETO36682.1 - 5.3e-05 22.4 0.2 5.3e-05 22.4 0.1 3.7 4 0 0 4 4 4 2 PHD-finger zf-HC5HC2H PF13771.1 ETO36682.1 - 0.00075 19.6 0.5 0.00075 19.6 0.3 5.6 4 3 2 6 6 6 2 PHD-like zinc-binding domain C1_1 PF00130.17 ETO36682.1 - 0.018 14.7 2.1 0.018 14.7 1.5 5.2 5 0 0 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H_2 PF13832.1 ETO36682.1 - 0.045 13.7 0.3 0.045 13.7 0.2 5.7 3 2 2 5 5 5 0 PHD-zinc-finger like domain DUF2335 PF10097.4 ETO36682.1 - 0.34 10.5 0.0 0.34 10.5 0.0 1.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2335) PHD PF00628.24 ETO36682.1 - 0.53 10.0 25.5 0.29 10.8 3.6 5.2 5 1 0 5 5 5 0 PHD-finger Exo_endo_phos_2 PF14529.1 ETO36683.1 - 3.5e-17 62.1 0.1 8.5e-17 60.8 0.1 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase BAF PF02961.9 ETO36684.1 - 0.011 16.0 0.1 0.018 15.3 0.1 1.5 1 1 0 1 1 1 0 Barrier to autointegration factor RVT_1 PF00078.22 ETO36685.1 - 6e-08 32.3 0.2 6e-07 29.0 0.0 2.1 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Njmu-R1 PF15053.1 ETO36686.1 - 0.031 13.0 0.0 0.041 12.6 0.0 1.2 1 0 0 1 1 1 0 Mjmu-R1-like protein family WD40 PF00400.27 ETO36686.1 - 0.046 13.6 0.0 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 WD domain, G-beta repeat WD40 PF00400.27 ETO36687.1 - 2e-29 100.3 10.9 7.9e-10 38.2 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO36687.1 - 1.8e-08 33.0 0.6 8.5e-05 20.8 0.5 3.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO36687.1 - 0.00069 18.4 0.6 0.34 9.6 0.0 2.9 1 1 1 3 3 3 2 Nup133 N terminal like SprB PF13573.1 ETO36687.1 - 0.095 12.3 1.3 0.94 9.1 0.1 2.5 2 0 0 2 2 2 0 SprB repeat WD40 PF00400.27 ETO36688.1 - 3.2e-74 242.3 9.7 2e-14 52.7 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat PD40 PF07676.7 ETO36688.1 - 1.8e-09 37.0 4.5 4.2 7.1 0.0 7.1 7 0 0 7 7 7 3 WD40-like Beta Propeller Repeat Nup160 PF11715.3 ETO36688.1 - 2.5e-07 29.2 0.1 0.093 10.8 0.0 4.5 1 1 2 3 3 3 3 Nucleoporin Nup120/160 DPPIV_N PF00930.16 ETO36688.1 - 0.00012 20.7 0.0 6.4 5.2 0.0 4.4 1 1 3 5 5 5 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Proteasome_A_N PF10584.4 ETO36688.1 - 0.0011 18.2 2.2 45 3.4 0.0 5.2 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Coatomer_WDAD PF04053.9 ETO36688.1 - 0.002 16.9 0.1 0.018 13.8 0.0 2.0 1 1 0 2 2 2 1 Coatomer WD associated region PQQ_2 PF13360.1 ETO36688.1 - 0.0037 16.7 0.0 0.25 10.7 0.0 2.8 1 1 0 1 1 1 1 PQQ-like domain DUF1258 PF06869.7 ETO36688.1 - 0.0047 16.0 4.0 1.7 7.6 0.0 3.6 3 1 1 4 4 4 1 Protein of unknown function (DUF1258) Resistin PF06954.6 ETO36688.1 - 0.0057 16.8 1.6 59 4.0 0.0 4.8 3 1 2 5 5 5 0 Resistin F420_ligase PF01996.11 ETO36688.1 - 0.016 14.2 0.0 3.5 6.6 0.0 3.2 2 1 0 2 2 2 0 F420-0:Gamma-glutamyl ligase DUF2344 PF10105.4 ETO36689.1 - 0.2 11.1 4.4 0.34 10.3 3.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) WD40 PF00400.27 ETO36690.1 - 4.6e-76 248.2 12.0 3.3e-13 48.9 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETO36690.1 - 4.2e-17 62.4 0.0 0.00022 20.9 0.0 3.7 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO36690.1 - 4.5e-08 31.6 7.0 0.097 10.7 0.5 5.5 1 1 4 5 5 5 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO36690.1 - 7.9e-08 30.9 1.4 0.08 11.2 0.0 4.0 1 1 2 4 4 4 4 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 ETO36690.1 - 4.2e-07 29.0 6.5 0.37 9.4 0.1 4.9 1 1 3 4 4 4 3 Nup133 N terminal like PD40 PF07676.7 ETO36690.1 - 5.3e-06 25.9 4.6 1.4 8.6 0.0 5.3 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO36690.1 - 5.4e-05 22.7 0.7 0.00023 20.6 0.4 2.1 1 1 1 2 2 2 2 PQQ-like domain Nbas_N PF15492.1 ETO36690.1 - 0.00024 20.3 2.3 1.2 8.1 0.0 4.1 2 2 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal DPPIV_N PF00930.16 ETO36690.1 - 0.0087 14.6 0.1 4.5 5.7 0.0 3.7 1 1 2 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Coatomer_WDAD PF04053.9 ETO36690.1 - 0.019 13.8 3.2 3.8 6.1 0.1 2.9 2 1 1 3 3 3 0 Coatomer WD associated region Gmad1 PF10647.4 ETO36690.1 - 0.064 12.6 0.0 2.1 7.6 0.0 2.7 2 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain DUF1652 PF07865.6 ETO36690.1 - 0.068 12.7 0.0 44 3.7 0.0 4.1 5 0 0 5 5 5 0 Protein of unknown function (DUF1652) PHZA_PHZB PF03284.8 ETO36690.1 - 0.13 11.3 0.0 3.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Phenazine biosynthesis protein A/B CMV_1a PF12467.3 ETO36691.1 - 1.9 8.8 11.0 5.7 7.2 0.4 2.2 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family LsmAD PF06741.8 ETO36691.1 - 4.2 7.5 9.3 0.89 9.6 0.5 2.5 2 1 0 2 2 2 0 LsmAD domain UQ_con PF00179.21 ETO36693.1 - 7.1e-14 51.4 1.1 4.5e-10 39.0 0.4 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 ETO36693.1 - 0.0014 18.4 0.1 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 ETO36693.1 - 0.015 15.1 0.1 0.023 14.6 0.1 1.3 1 0 0 1 1 1 0 RWD domain ABC_tran PF00005.22 ETO36694.1 - 1.8e-28 99.5 0.3 3.3e-28 98.6 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 ETO36694.1 - 0.00011 22.2 0.9 0.1 12.5 0.0 2.6 2 1 1 3 3 3 2 AAA domain SMC_N PF02463.14 ETO36694.1 - 0.00043 19.5 1.2 0.13 11.4 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 ETO36694.1 - 0.0042 17.1 0.0 0.0082 16.1 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 ETO36694.1 - 0.0076 15.7 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF87 PF01935.12 ETO36694.1 - 0.017 14.9 0.7 0.039 13.7 0.5 1.9 1 1 0 1 1 1 0 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 ETO36694.1 - 0.018 14.9 0.3 0.048 13.6 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.1 ETO36694.1 - 0.048 13.8 0.1 0.58 10.3 0.1 2.4 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 ETO36694.1 - 0.054 13.9 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Bac_rhamnosid PF05592.6 ETO36694.1 - 0.093 10.9 0.0 0.13 10.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase D123 PF07065.9 ETO36696.1 - 2.4e-08 33.4 0.9 2.4e-08 33.4 0.7 3.7 3 1 2 5 5 5 1 D123 Pex14_N PF04695.8 ETO36696.1 - 0.14 12.1 2.6 2.1 8.3 1.2 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Secretin_N_2 PF07655.8 ETO36696.1 - 0.83 10.0 19.7 2.7 8.4 8.3 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain ELFV_dehydrog_N PF02812.13 ETO36697.1 - 8.8e-18 64.1 0.0 1.5e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.16 ETO36698.1 - 6.8e-43 146.9 0.0 1e-39 136.6 0.0 2.1 2 0 0 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 ETO36698.1 - 1.1e-09 37.9 0.0 2.7e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Sulfotransfer_1 PF00685.22 ETO36699.1 - 8.8e-07 28.4 3.1 0.00029 20.2 2.1 2.8 1 1 0 1 1 1 1 Sulfotransferase domain HDAC4_Gln PF12203.3 ETO36700.1 - 1.5 8.8 10.5 0.046 13.6 1.6 2.0 2 0 0 2 2 2 0 Glutamine rich N terminal domain of histone deacetylase 4 AAA_23 PF13476.1 ETO36700.1 - 7.2 6.8 10.3 9.8 6.4 7.1 1.1 1 0 0 1 1 1 0 AAA domain LANC_like PF05147.8 ETO36702.1 - 7.9e-53 179.2 1.1 1.3e-49 168.6 0.4 2.1 2 0 0 2 2 2 2 Lanthionine synthetase C-like protein DUF1767 PF08585.7 ETO36703.1 - 0.019 15.2 0.1 0.074 13.3 0.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1767) WD40 PF00400.27 ETO36704.1 - 5.9e-64 209.8 29.5 1.1e-12 47.3 0.0 7.3 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO36704.1 - 2.9e-11 42.2 6.5 0.007 14.5 0.8 4.6 1 1 4 5 5 5 4 Nucleoporin Nup120/160 HAD PF12710.2 ETO36704.1 - 0.24 11.5 2.8 63 3.6 1.9 3.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase WD40 PF00400.27 ETO36705.1 - 1.5e-57 189.5 12.6 3.2e-13 48.9 0.2 5.0 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 ETO36705.1 - 9.2e-10 38.5 0.1 5.1e-06 26.3 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO36705.1 - 6.6e-07 27.8 2.3 0.033 12.3 0.1 3.3 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO36705.1 - 5.3e-05 22.1 6.9 0.12 11.0 0.2 3.9 1 1 3 4 4 4 3 Nup133 N terminal like PD40 PF07676.7 ETO36705.1 - 0.00012 21.6 5.7 2.3 7.9 0.0 4.6 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO36705.1 - 0.00038 20.0 0.1 0.021 14.3 0.0 2.2 1 1 1 2 2 2 1 PQQ-like domain DUF1258 PF06869.7 ETO36705.1 - 0.0012 18.0 0.4 0.59 9.1 0.0 2.2 1 1 0 2 2 2 2 Protein of unknown function (DUF1258) DPPIV_N PF00930.16 ETO36705.1 - 0.0043 15.6 0.1 5.6 5.4 0.0 3.5 1 1 3 4 4 4 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nbas_N PF15492.1 ETO36705.1 - 0.011 14.8 0.3 0.077 12.0 0.1 2.3 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal BBS2_Mid PF14783.1 ETO36705.1 - 0.017 14.8 1.0 11 5.8 0.0 3.9 2 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Lactonase PF10282.4 ETO36705.1 - 0.046 12.7 0.0 1.2 8.0 0.0 2.6 1 1 1 3 3 3 0 Lactonase, 7-bladed beta-propeller Resistin PF06954.6 ETO36705.1 - 0.085 13.1 0.0 4.7 7.5 0.0 2.6 1 1 1 2 2 2 0 Resistin DUF727 PF05303.7 ETO36705.1 - 0.11 12.2 0.2 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF727) Proteasome_A_N PF10584.4 ETO36705.1 - 0.46 9.8 4.9 32 3.9 0.2 3.4 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Kelch_6 PF13964.1 ETO36706.1 - 4.7e-06 26.5 4.8 5.2e-05 23.2 0.0 4.0 4 1 1 5 5 5 1 Kelch motif Kelch_4 PF13418.1 ETO36706.1 - 5e-06 26.1 0.0 0.017 14.8 0.0 3.0 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO36706.1 - 5e-05 22.8 0.4 0.027 14.2 0.0 3.2 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.20 ETO36706.1 - 0.0014 18.1 0.7 0.004 16.6 0.0 2.2 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 ETO36706.1 - 0.0061 16.7 0.0 0.016 15.3 0.0 1.8 1 0 0 1 1 1 1 Galactose oxidase, central domain WD40 PF00400.27 ETO36706.1 - 0.0061 16.3 0.0 0.033 14.0 0.0 2.3 1 0 0 1 1 1 1 WD domain, G-beta repeat Kelch_5 PF13854.1 ETO36706.1 - 0.012 15.5 0.3 0.26 11.2 0.0 3.4 3 0 0 3 3 3 0 Kelch motif PD40 PF07676.7 ETO36706.1 - 0.088 12.5 0.2 13 5.5 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat PBP1_TM PF14812.1 ETO36709.1 - 0.056 13.7 4.0 0.082 13.2 2.8 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TAF4 PF05236.9 ETO36709.1 - 0.35 10.0 8.9 0.43 9.8 6.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Sec62 PF03839.11 ETO36709.1 - 0.36 10.2 3.2 0.39 10.0 2.2 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 OmpH PF03938.9 ETO36709.1 - 0.44 10.4 6.4 0.48 10.3 4.4 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1682 PF07946.9 ETO36709.1 - 0.47 9.2 10.6 0.57 8.9 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) NPIP PF06409.6 ETO36709.1 - 0.49 9.0 3.6 0.55 8.9 2.5 1.1 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) DUF3654 PF12376.3 ETO36709.1 - 0.62 9.8 8.5 0.85 9.4 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3654) DUF4337 PF14235.1 ETO36709.1 - 1.3 8.8 6.9 1.6 8.5 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF3451 PF11933.3 ETO36709.1 - 1.5 8.5 7.8 1.8 8.3 5.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3451) Inhibitor_I10 PF12559.3 ETO36709.1 - 1.6 9.0 4.7 3.6 7.9 3.3 1.7 1 1 0 1 1 1 0 Serine endopeptidase inhibitors DUF3767 PF12597.3 ETO36709.1 - 2 8.0 5.3 2.8 7.6 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) Cwf_Cwc_15 PF04889.7 ETO36709.1 - 2.1 7.9 13.3 2.5 7.7 9.2 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ank_4 PF13637.1 ETO36710.1 - 8.7e-15 54.7 0.6 1.2e-08 35.1 0.0 4.4 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETO36710.1 - 1.3e-13 50.7 0.6 1.2e-10 41.2 0.0 3.6 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETO36710.1 - 1.1e-12 48.1 0.0 2.4e-11 43.8 0.0 2.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETO36710.1 - 3.2e-11 42.3 0.2 1.2e-07 31.2 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.25 ETO36710.1 - 3e-10 39.3 0.2 1.4e-08 34.0 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat LRR_6 PF13516.1 ETO36711.1 - 9e-07 28.3 2.2 0.00062 19.5 0.0 4.6 3 1 1 4 4 4 2 Leucine Rich repeat LRR_8 PF13855.1 ETO36711.1 - 6.5e-05 22.6 0.8 0.16 11.7 0.0 3.9 3 0 0 3 3 3 2 Leucine rich repeat MFS_1 PF07690.11 ETO36712.1 - 0.00033 19.4 1.3 0.0033 16.1 1.8 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2142 PF09913.4 ETO36712.1 - 0.00043 19.0 2.6 0.00054 18.7 1.8 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2142) DUF4097 PF13349.1 ETO36712.1 - 0.0036 16.8 1.0 0.21 11.1 0.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4097) DUF4131 PF13567.1 ETO36712.1 - 0.0066 15.8 1.9 0.089 12.2 1.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4131) Ni_hydr_CYTB PF01292.15 ETO36712.1 - 0.013 14.8 1.6 0.26 10.6 0.7 2.1 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 DUF2207 PF09972.4 ETO36712.1 - 0.054 12.0 8.0 0.033 12.7 4.4 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) RDD PF06271.7 ETO36712.1 - 0.13 12.1 7.7 0.13 12.1 3.5 2.0 2 0 0 2 2 2 0 RDD family UPF0104 PF03706.8 ETO36712.1 - 0.48 9.6 10.6 0.41 9.8 6.4 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0104) EphA2_TM PF14575.1 ETO36712.1 - 2.1 8.7 6.2 9.3 6.7 0.0 2.7 2 1 1 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF2140 PF09911.4 ETO36712.1 - 4.8 6.3 11.7 0.066 12.3 0.9 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2140) Occludin_ELL PF07303.8 ETO36713.1 - 0.028 15.1 2.4 0.095 13.4 0.5 2.5 2 0 0 2 2 2 0 Occludin homology domain adh_short_C2 PF13561.1 ETO36714.1 - 0.066 12.9 0.2 0.098 12.4 0.1 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase ubiquitin PF00240.18 ETO36715.1 - 7e-13 47.7 0.4 2e-12 46.3 0.3 1.7 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 ETO36715.1 - 3.1e-05 23.5 0.1 3.1e-05 23.5 0.0 2.5 3 1 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 ETO36715.1 - 0.038 14.2 0.0 0.1 12.8 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain DDE_Tnp_1_6 PF13751.1 ETO36715.1 - 0.18 11.8 2.3 0.61 10.1 0.0 2.1 1 1 1 2 2 2 0 Transposase DDE domain SPC25 PF06703.6 ETO36716.1 - 0.11 12.1 3.8 0.12 12.0 1.7 1.7 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) AzlD PF05437.7 ETO36716.1 - 0.36 10.8 4.9 0.93 9.4 3.4 1.7 1 0 0 1 1 1 0 Branched-chain amino acid transport protein (AzlD) DUF560 PF04575.8 ETO36717.1 - 0.015 14.5 0.4 0.02 14.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF560) PhnJ PF06007.6 ETO36717.1 - 0.015 14.1 0.2 0.017 13.9 0.1 1.1 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ SATase_N PF06426.9 ETO36717.1 - 0.025 14.8 0.6 1.3 9.3 0.2 2.2 2 0 0 2 2 2 0 Serine acetyltransferase, N-terminal zf-C4pol PF14260.1 ETO36718.1 - 0.035 14.0 2.9 3.4 7.7 0.2 2.3 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta EST1 PF10374.4 ETO36718.1 - 0.15 12.0 4.1 0.064 13.2 1.1 1.6 1 1 1 2 2 2 0 Telomerase activating protein Est1 WD40 PF00400.27 ETO36719.1 - 1.1e-07 31.4 2.4 0.00028 20.6 1.0 3.1 2 1 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO36719.1 - 0.0007 17.8 0.1 0.00089 17.5 0.1 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Herpes_UL73 PF03554.8 ETO36719.1 - 0.076 12.8 0.4 0.41 10.5 0.1 2.0 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein V-set_CD47 PF08204.6 ETO36719.1 - 0.088 12.5 0.2 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain Orthoreo_P17 PF07272.6 ETO36720.1 - 0.0032 17.2 1.0 1.4 8.7 0.0 2.4 1 1 1 2 2 2 2 Orthoreovirus P17 protein HTH_44 PF14641.1 ETO36720.1 - 0.048 13.6 2.8 0.072 13.0 0.4 2.2 1 1 1 2 2 2 0 Helix-turn-helix DNA-binding domain of SPT6 SelP_N PF04592.9 ETO36721.1 - 2.9 7.1 19.3 6.9 5.9 13.4 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region F5_F8_type_C PF00754.20 ETO36722.1 - 7.8e-05 22.5 7.1 0.11 12.2 0.2 3.2 3 0 0 3 3 3 2 F5/8 type C domain DUF2399 PF09664.5 ETO36722.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) F5_F8_type_C PF00754.20 ETO36723.1 - 2e-08 34.1 0.9 0.0016 18.2 0.2 2.3 2 0 0 2 2 2 2 F5/8 type C domain zf-RING_2 PF13639.1 ETO36723.1 - 2.6e-07 30.3 3.4 2.6e-07 30.3 2.4 4.4 5 1 0 5 5 5 1 Ring finger domain zf-RING_5 PF14634.1 ETO36723.1 - 0.00038 20.1 2.9 0.00038 20.1 2.0 3.9 2 1 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 ETO36723.1 - 0.0083 16.2 4.8 0.0083 16.2 3.4 3.8 3 2 0 3 3 3 1 RING-H2 zinc finger PH_6 PF15406.1 ETO36724.1 - 0.0016 18.4 0.0 0.0022 18.0 0.0 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain Sec3-PIP2_bind PF15277.1 ETO36724.1 - 0.018 14.9 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH PH_9 PF15410.1 ETO36724.1 - 0.043 13.9 0.0 0.062 13.4 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain PH PF00169.24 ETO36724.1 - 0.059 13.5 0.0 0.074 13.2 0.0 1.2 1 0 0 1 1 1 0 PH domain ETRAMP PF09716.5 ETO36725.1 - 0.013 15.4 0.0 0.06 13.2 0.0 2.0 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) RVT_1 PF00078.22 ETO36726.1 - 1.9e-09 37.1 0.2 6.2e-09 35.5 0.2 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Vps16_C PF04840.7 ETO36727.1 - 4e-23 81.8 1.9 4.4e-23 81.7 1.3 1.0 1 0 0 1 1 1 1 Vps16, C-terminal region Clathrin PF00637.15 ETO36727.1 - 2.1e-05 24.1 1.0 3.7e-05 23.3 0.7 1.4 1 0 0 1 1 1 1 Region in Clathrin and VPS DUF1195 PF06708.6 ETO36727.1 - 0.046 13.1 0.1 0.066 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) RNR_N PF08343.5 ETO36727.1 - 0.11 12.3 0.3 0.67 9.7 0.0 2.2 2 0 0 2 2 2 0 Ribonucleotide reductase N-terminal E1_DerP2_DerF2 PF02221.10 ETO36728.1 - 3.8e-13 49.8 3.6 4.8e-13 49.5 2.5 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 ETO36728.1 - 5.2e-06 26.5 2.2 5.4e-05 23.2 1.5 2.1 1 1 0 1 1 1 1 ML-like domain PKD_channel PF08016.7 ETO36729.1 - 0.0018 16.7 0.2 0.0023 16.4 0.1 1.1 1 0 0 1 1 1 1 Polycystin cation channel Kelch_1 PF01344.20 ETO36730.1 - 6.8e-09 35.1 0.5 0.00055 19.4 0.1 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO36730.1 - 1.1e-08 34.9 1.3 0.00082 19.4 0.0 4.1 3 1 1 4 4 4 3 Kelch motif Kelch_2 PF07646.10 ETO36730.1 - 2.3e-07 30.2 3.3 0.00052 19.6 0.1 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO36730.1 - 3.5e-05 23.4 0.0 0.0062 16.2 0.0 3.0 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETO36730.1 - 0.00012 22.0 0.0 0.013 15.6 0.0 3.4 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO36730.1 - 0.0064 16.4 0.2 6.5 6.8 0.1 4.2 4 0 0 4 4 4 1 Kelch motif DUF3926 PF13080.1 ETO36730.1 - 0.036 13.6 0.2 0.099 12.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3926) TPR_12 PF13424.1 ETO36733.1 - 6e-44 147.8 10.9 3.4e-16 58.9 0.3 2.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO36733.1 - 2.1e-22 78.5 15.9 6.3e-10 38.5 1.2 3.0 1 1 2 3 3 3 3 TPR repeat TPR_8 PF13181.1 ETO36733.1 - 5.3e-15 53.9 10.9 8e-07 28.4 1.1 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETO36733.1 - 1.4e-14 52.9 12.9 8.9e-06 25.0 1.2 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO36733.1 - 3.7e-13 48.2 10.0 0.0021 17.8 0.6 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETO36733.1 - 5.7e-13 48.3 0.0 0.0011 18.8 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO36733.1 - 2.1e-10 39.5 0.9 0.028 14.1 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETO36733.1 - 1e-05 25.3 7.2 1.6 9.0 0.1 5.1 4 2 0 4 4 4 3 Tetratricopeptide repeat MIT PF04212.13 ETO36733.1 - 0.0082 16.0 5.5 1.7 8.6 0.0 4.1 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_14 PF13428.1 ETO36733.1 - 0.01 16.4 0.3 3.8 8.3 0.0 3.8 4 1 1 5 5 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETO36733.1 - 0.015 15.6 7.5 0.36 11.3 0.1 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat Apc3 PF12895.2 ETO36733.1 - 0.074 13.2 4.2 6.9 6.8 0.2 2.7 1 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF2225 PF09986.4 ETO36733.1 - 0.18 11.2 4.7 0.11 11.9 1.3 2.1 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_16 PF13432.1 ETO36733.1 - 0.25 12.0 1.3 8.2 7.2 0.3 3.1 3 1 1 4 4 3 0 Tetratricopeptide repeat DUF3745 PF12560.3 ETO36734.1 - 0.096 12.3 0.2 1.8 8.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3745) Cytochrom_C550 PF14495.1 ETO36735.1 - 0.16 11.4 1.4 0.27 10.6 0.9 1.5 1 1 0 1 1 1 0 Cytochrome c-550 domain ImmE5 PF11480.3 ETO36735.1 - 0.27 11.0 0.1 0.27 11.0 0.1 2.1 2 0 0 2 2 2 0 Colicin-E5 Imm protein Ribosomal_S27 PF01599.14 ETO36735.1 - 0.6 9.9 3.3 5.2 6.9 0.4 2.3 2 0 0 2 2 2 0 Ribosomal protein S27a Tetraspannin PF00335.15 ETO36735.1 - 4.3 6.5 8.2 5.4 6.2 5.7 1.1 1 0 0 1 1 1 0 Tetraspanin family RTBV_P12 PF06361.6 ETO36736.1 - 0.0084 16.3 1.4 0.011 15.9 0.3 1.6 1 1 1 2 2 2 1 Rice tungro bacilliform virus P12 protein HSBP1 PF06825.7 ETO36736.1 - 0.015 14.8 1.3 0.015 14.8 0.9 2.1 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Med11 PF10280.4 ETO36736.1 - 0.16 11.9 6.2 1.1 9.3 0.2 2.2 1 1 1 2 2 2 0 Mediator complex protein Tbf5 PF06331.7 ETO36736.1 - 1.1 9.1 5.1 0.92 9.3 2.2 1.8 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 WD40 PF00400.27 ETO36737.1 - 3.3e-10 39.4 0.7 0.0011 18.7 0.0 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF2340 PF10209.4 ETO36738.1 - 0.078 13.1 1.1 0.1 12.7 0.8 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) DUF3513 PF12026.3 ETO36739.1 - 1.5 8.3 8.9 2.1 7.8 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) Protocadherin PF08374.6 ETO36739.1 - 1.7 8.2 5.6 1.9 8.0 3.9 1.0 1 0 0 1 1 1 0 Protocadherin HAUS6_N PF14661.1 ETO36739.1 - 2.6 7.3 8.0 3 7.1 5.5 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus GPCR_chapero_1 PF11904.3 ETO36739.1 - 2.9 6.9 10.2 3.4 6.7 7.1 1.0 1 0 0 1 1 1 0 GPCR-chaperone Trypan_PARP PF05887.6 ETO36739.1 - 2.9 7.7 8.1 3.3 7.5 5.6 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Nop25 PF09805.4 ETO36739.1 - 3.3 7.7 19.2 4.3 7.4 13.3 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Hid1 PF12722.2 ETO36739.1 - 4.2 4.9 8.9 5.1 4.6 6.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF106 PF01956.11 ETO36739.1 - 6.8 6.1 5.3 8.3 5.9 3.7 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 Paf1 PF03985.8 ETO36739.1 - 8.8 4.9 18.5 10 4.7 12.8 1.1 1 0 0 1 1 1 0 Paf1 WD40 PF00400.27 ETO36740.1 - 1.8e-26 90.9 4.7 8.2e-10 38.1 0.0 4.1 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO36740.1 - 2.9e-05 22.4 0.5 0.19 9.7 0.0 2.9 1 1 2 3 3 3 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETO36740.1 - 0.0077 15.9 1.2 0.16 11.7 0.2 2.3 1 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 ETO36740.1 - 0.2 10.3 1.8 4.7 5.8 1.2 2.6 1 1 0 1 1 1 0 Nup133 N terminal like SelR PF01641.13 ETO36743.1 - 1.7e-29 102.0 2.5 4.2e-28 97.5 1.7 2.0 1 1 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.9 ETO36743.1 - 0.045 13.7 2.7 0.34 10.9 1.9 2.1 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly NTF2 PF02136.15 ETO36744.1 - 0.0017 18.7 1.1 0.0017 18.7 0.8 2.8 2 1 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain ERM PF00769.14 ETO36745.1 - 5e-08 32.7 68.0 0.0054 16.2 7.3 3.4 2 1 1 3 3 3 3 Ezrin/radixin/moesin family GAS PF13851.1 ETO36745.1 - 0.00033 19.9 70.7 0.023 13.8 13.4 4.5 2 1 2 4 4 4 3 Growth-arrest specific micro-tubule binding CCDC155 PF14662.1 ETO36745.1 - 0.00059 19.4 67.5 0.0094 15.5 19.9 4.7 1 1 3 4 4 4 1 Coiled-coil region of CCDC155 IncA PF04156.9 ETO36745.1 - 0.0016 18.0 73.0 0.18 11.3 12.4 4.1 1 1 3 4 4 4 3 IncA protein NTR2 PF15458.1 ETO36745.1 - 0.0024 17.1 3.1 0.0024 17.1 2.2 5.6 3 1 2 5 5 5 1 Nineteen complex-related protein 2 DMPK_coil PF08826.5 ETO36745.1 - 0.0041 16.9 1.0 0.0041 16.9 0.7 6.8 4 2 2 6 6 4 1 DMPK coiled coil domain like Val_tRNA-synt_C PF10458.4 ETO36745.1 - 0.0042 17.1 1.5 0.0042 17.1 1.0 7.2 5 4 2 7 7 7 2 Valyl tRNA synthetase tRNA binding arm CALCOCO1 PF07888.6 ETO36745.1 - 0.0043 15.4 50.1 0.0057 15.0 34.7 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Myosin_tail_1 PF01576.14 ETO36745.1 - 0.014 13.1 68.2 0.0064 14.2 37.6 2.6 2 1 0 2 2 2 0 Myosin tail TMF_TATA_bd PF12325.3 ETO36745.1 - 0.02 14.5 64.3 0.067 12.9 3.8 5.1 2 1 3 5 5 5 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.4 ETO36745.1 - 0.024 14.5 69.6 1.7 8.5 21.9 4.6 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.8 ETO36745.1 - 0.034 14.4 62.7 1.1 9.6 3.4 5.5 2 1 3 5 5 4 0 Protein of unknown function (DUF972) Tropomyosin_1 PF12718.2 ETO36745.1 - 0.044 13.6 78.7 0.035 13.9 4.8 4.5 2 1 2 4 4 4 0 Tropomyosin like APG6 PF04111.7 ETO36745.1 - 0.053 12.5 76.5 0.16 10.9 8.6 3.8 2 1 2 4 4 4 0 Autophagy protein Apg6 AAA_27 PF13514.1 ETO36745.1 - 0.18 9.4 55.5 0.46 8.1 30.8 2.8 2 1 0 2 2 2 0 AAA domain DUF869 PF05911.6 ETO36745.1 - 0.23 9.6 61.7 0.027 12.7 22.7 3.2 2 1 1 3 3 3 0 Plant protein of unknown function (DUF869) ATG16 PF08614.6 ETO36745.1 - 0.46 10.2 71.0 0.33 10.7 3.1 3.8 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF2353 PF09789.4 ETO36745.1 - 0.78 8.9 50.5 1.2 8.2 10.3 3.1 1 1 1 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) LPP PF04728.8 ETO36745.1 - 1 9.2 22.3 0.36 10.6 4.0 4.6 3 2 0 3 3 3 0 Lipoprotein leucine-zipper AAA_13 PF13166.1 ETO36745.1 - 1.1 7.5 69.5 0.057 11.8 27.0 3.0 2 1 1 3 3 3 0 AAA domain ADIP PF11559.3 ETO36745.1 - 1.2 9.0 81.2 0.14 12.0 6.7 5.2 2 1 3 5 5 5 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.7 ETO36745.1 - 1.2 8.9 40.0 0.059 13.1 5.0 4.3 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) Filament PF00038.16 ETO36745.1 - 1.4 8.3 61.2 0.48 9.8 28.5 2.7 1 1 1 2 2 2 0 Intermediate filament protein COG2 PF06148.6 ETO36745.1 - 1.4 8.7 40.2 1.8 8.4 7.7 4.7 2 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Mnd1 PF03962.10 ETO36745.1 - 2.4 7.7 66.9 0.49 10.0 9.0 4.3 2 1 2 4 4 4 0 Mnd1 family Tektin PF03148.9 ETO36745.1 - 6 5.3 61.2 0.049 12.1 1.7 5.3 2 1 4 6 6 6 0 Tektin family DivIC PF04977.10 ETO36745.1 - 6.2 6.3 71.1 0.32 10.4 4.1 7.8 2 2 5 7 7 7 0 Septum formation initiator MSC PF09402.5 ETO36746.1 - 0.083 11.5 11.0 0.12 11.0 7.6 1.3 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain TMEM51 PF15345.1 ETO36746.1 - 3.5 7.2 17.2 4.5 6.8 12.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Caps_synth_CapC PF14102.1 ETO36747.1 - 0.035 14.2 0.3 0.05 13.7 0.2 1.2 1 0 0 1 1 1 0 Capsule biosynthesis CapC adh_short PF00106.20 ETO36748.1 - 6.5e-15 55.4 0.0 1.3e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETO36748.1 - 3.9e-05 23.4 0.1 6.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETO36748.1 - 0.0012 18.6 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Saccharop_dh PF03435.13 ETO36748.1 - 0.0066 15.4 0.1 0.0093 14.9 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 ETO36748.1 - 0.015 15.3 0.2 0.024 14.6 0.2 1.3 1 0 0 1 1 1 0 NADH(P)-binding CobD_Cbib PF03186.8 ETO36748.1 - 0.079 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 CobD/Cbib protein Polysacc_synt_2 PF02719.10 ETO36748.1 - 0.39 9.5 2.6 0.75 8.6 0.3 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Methyltransf_31 PF13847.1 ETO36751.1 - 4.4e-16 58.8 0.6 7e-16 58.1 0.4 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETO36751.1 - 5.5e-10 39.8 0.0 7.7e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETO36751.1 - 1.2e-09 38.5 0.0 2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETO36751.1 - 1.1e-07 32.2 0.0 1.9e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETO36751.1 - 1.6e-07 30.6 0.0 2.3e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 ETO36751.1 - 7.3e-07 29.0 0.0 9.6e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 ETO36751.1 - 2.3e-06 26.8 0.0 3.1e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 ETO36751.1 - 0.00024 21.4 0.0 0.00042 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 ETO36751.1 - 0.00091 18.9 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETO36751.1 - 0.003 16.9 0.0 0.005 16.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 ETO36751.1 - 0.004 17.1 0.0 0.0063 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.11 ETO36751.1 - 0.0044 15.9 1.4 0.014 14.2 0.3 1.8 2 0 0 2 2 2 1 mRNA capping enzyme FtsJ PF01728.14 ETO36751.1 - 0.006 16.5 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_PK PF05891.7 ETO36751.1 - 0.023 13.9 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_9 PF08003.6 ETO36751.1 - 0.035 12.8 0.0 0.051 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PCMT PF01135.14 ETO36751.1 - 0.037 13.5 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FmrO PF07091.6 ETO36751.1 - 0.13 11.2 0.0 0.24 10.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) PrmA PF06325.8 ETO36751.1 - 0.14 11.2 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) WD40 PF00400.27 ETO36752.1 - 1.7e-61 202.0 26.1 7.4e-11 41.4 0.4 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO36752.1 - 4.6e-07 28.3 4.4 0.035 12.2 0.2 4.3 1 1 2 4 4 4 4 Nucleoporin Nup120/160 WD40 PF00400.27 ETO36753.1 - 3.2e-72 236.0 28.0 2.9e-11 42.8 0.1 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO36753.1 - 1.5e-05 23.9 6.5 0.1 11.2 0.1 4.1 1 1 3 4 4 4 3 Nup133 N terminal like Kelch_6 PF13964.1 ETO36753.1 - 2.1e-05 24.4 4.2 0.0021 18.1 0.1 4.2 4 1 1 5 5 5 1 Kelch motif PQQ_2 PF13360.1 ETO36753.1 - 0.0016 17.9 1.0 0.0048 16.3 0.3 2.1 2 1 0 2 2 2 1 PQQ-like domain DUF244 PF03112.9 ETO36753.1 - 0.0081 15.7 1.1 0.0081 15.7 0.8 2.3 3 0 0 3 3 3 1 Uncharacterized protein family (ORF7) DUF MinC_C PF03775.11 ETO36753.1 - 0.029 14.0 0.0 0.1 12.2 0.0 1.9 1 0 0 1 1 1 0 Septum formation inhibitor MinC, C-terminal domain Proteasome_A_N PF10584.4 ETO36753.1 - 0.038 13.3 3.0 4.8 6.5 0.0 4.4 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Kelch_1 PF01344.20 ETO36753.1 - 0.061 12.8 0.5 8.7 5.9 0.0 3.6 3 0 0 3 3 3 0 Kelch motif PD40 PF07676.7 ETO36753.1 - 0.099 12.3 5.6 2.8 7.6 0.0 4.7 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Cwf_Cwc_15 PF04889.7 ETO36753.1 - 0.11 12.2 5.6 1 9.0 0.0 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein TPR_12 PF13424.1 ETO36754.1 - 3e-35 120.0 9.9 2e-15 56.4 1.2 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETO36754.1 - 1.4e-22 79.1 12.0 6.9e-11 41.6 1.9 3.6 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETO36754.1 - 9.7e-21 72.4 27.4 4.7e-07 29.1 0.6 5.0 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO36754.1 - 1.5e-20 71.3 6.2 1.7e-05 24.2 0.1 5.0 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO36754.1 - 5.3e-19 67.4 0.0 1.4e-05 24.8 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETO36754.1 - 2.1e-17 61.5 21.7 1.9e-05 24.0 1.4 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO36754.1 - 6.4e-16 56.9 23.9 8.9e-05 22.1 1.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat SNAP PF14938.1 ETO36754.1 - 5.9e-09 35.4 4.2 5.9e-09 35.4 2.9 2.0 2 0 0 2 2 1 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.1 ETO36754.1 - 2.9e-06 27.3 5.7 6 7.5 0.2 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETO36754.1 - 4.3e-06 27.2 0.1 0.00095 19.7 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETO36754.1 - 8.5e-06 25.9 0.3 2.1 9.2 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETO36754.1 - 0.00021 21.2 5.6 0.031 14.4 0.0 4.6 4 1 0 4 4 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO36754.1 - 0.00039 19.6 0.3 2.5 7.4 0.0 3.6 3 0 0 3 3 3 2 SHNi-TPR TPR_19 PF14559.1 ETO36754.1 - 0.00065 19.9 2.1 0.0018 18.5 0.7 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 ETO36754.1 - 0.003 17.6 10.1 0.3 11.2 6.7 3.3 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 ETO36754.1 - 1.8 8.4 12.1 3.1 7.6 0.8 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Rho_GDI PF02115.12 ETO36755.1 - 4.8e-57 192.6 1.4 5.4e-57 192.4 0.9 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Ligase_CoA PF00549.14 ETO36756.1 - 6.7e-24 84.2 0.9 9e-24 83.8 0.1 1.5 2 0 0 2 2 2 1 CoA-ligase CoA_binding PF02629.14 ETO36756.1 - 9.6e-22 77.3 1.7 2.6e-20 72.7 0.0 2.4 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.1 ETO36756.1 - 7.7e-08 32.0 0.0 1.3e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain His_Phos_1 PF00300.17 ETO36757.1 - 4.2e-23 82.1 0.0 1.6e-22 80.3 0.0 2.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) zf-C3HC4 PF00097.20 ETO36757.1 - 0.56 9.9 6.8 0.12 12.0 1.4 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETO36757.1 - 3.6 7.6 9.1 1.1 9.3 3.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FGGY_N PF00370.16 ETO36759.1 - 1.4e-43 148.9 1.7 1.9e-43 148.5 1.2 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Gtr1_RagA PF04670.7 ETO36760.1 - 0.068 12.2 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region LRR_4 PF12799.2 ETO36762.1 - 1.4e-09 37.3 7.9 0.014 14.9 0.0 3.4 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.7 ETO36762.1 - 0.00036 20.4 0.3 0.00073 19.4 0.2 1.6 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_8 PF13855.1 ETO36762.1 - 0.0053 16.4 4.4 0.59 9.9 0.1 4.0 4 0 0 4 4 4 1 Leucine rich repeat LRR_1 PF00560.28 ETO36762.1 - 0.76 10.0 0.1 0.76 10.0 0.1 4.9 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_8 PF13855.1 ETO36763.1 - 1.9e-06 27.5 10.7 0.00081 19.0 1.4 3.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 ETO36763.1 - 7.1e-06 25.5 13.5 1.7e-05 24.2 0.8 5.3 3 1 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETO36763.1 - 0.00032 20.3 28.9 0.88 9.8 0.0 8.8 9 0 0 9 9 9 4 Leucine Rich Repeat LRR_7 PF13504.1 ETO36763.1 - 0.95 9.9 8.4 56 4.6 0.1 5.9 5 0 0 5 5 5 0 Leucine rich repeat DUF4200 PF13863.1 ETO36764.1 - 0.21 11.5 2.8 0.35 10.8 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) RXT2_N PF08595.6 ETO36764.1 - 0.26 11.0 5.2 0.44 10.3 3.6 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 ETO36764.1 - 1.2 8.6 4.2 2.1 7.8 2.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin Tom22 PF04281.8 ETO36764.1 - 1.6 8.2 4.8 2.5 7.6 3.3 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DUF2457 PF10446.4 ETO36764.1 - 7.3 5.1 8.4 9.3 4.8 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) F_actin_cap_B PF01115.12 ETO36765.1 - 1.4e-76 256.8 0.4 3.2e-76 255.7 0.2 1.5 1 1 0 1 1 1 1 F-actin capping protein, beta subunit WD40 PF00400.27 ETO36766.1 - 7.8e-80 260.1 28.8 1.1e-13 50.5 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO36766.1 - 0.00018 20.4 8.5 0.097 11.4 0.0 4.3 2 1 2 4 4 4 3 Nup133 N terminal like PQQ_2 PF13360.1 ETO36766.1 - 0.00031 20.2 2.5 2 7.8 0.0 3.7 2 1 0 3 3 3 3 PQQ-like domain Cytochrom_D1 PF02239.11 ETO36766.1 - 0.00097 17.5 1.5 0.19 9.9 0.2 2.8 1 1 2 4 4 4 2 Cytochrome D1 heme domain Resistin PF06954.6 ETO36766.1 - 0.0018 18.5 4.2 2.4 8.5 0.0 4.9 3 2 3 6 6 6 1 Resistin DUF3732 PF12532.3 ETO36766.1 - 0.029 13.9 0.0 6.6 6.1 0.0 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF3732) PD40 PF07676.7 ETO36766.1 - 0.63 9.7 15.2 10 5.8 0.0 5.9 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 ETO36767.1 - 8.1e-20 69.9 6.7 4.4e-09 35.8 0.3 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF4221 PF13970.1 ETO36767.1 - 0.0011 18.3 3.0 0.0015 17.9 2.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4221) Nup160 PF11715.3 ETO36767.1 - 0.0079 14.3 0.1 0.074 11.1 0.0 1.9 1 1 1 2 2 2 2 Nucleoporin Nup120/160 tRNA-synt_His PF13393.1 ETO36768.1 - 6.5e-31 107.5 0.0 1e-30 106.9 0.0 1.3 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 ETO36768.1 - 1.4e-19 70.3 0.1 3.1e-19 69.1 0.1 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 ETO36768.1 - 9.8e-06 25.4 0.1 3.4e-05 23.6 0.1 1.9 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2d PF01409.15 ETO36768.1 - 0.0029 16.8 0.0 0.0047 16.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) Peptidase_C37 PF05416.7 ETO36768.1 - 0.012 13.9 0.2 0.021 13.1 0.1 1.3 1 0 0 1 1 1 0 Southampton virus-type processing peptidase YflT PF11181.3 ETO36768.1 - 0.017 15.2 4.8 0.033 14.3 0.5 2.9 3 0 0 3 3 3 0 Heat induced stress protein YflT Tn7_Tnp_TnsA_N PF08722.6 ETO36768.1 - 0.13 12.2 2.9 0.54 10.2 0.0 3.1 3 0 0 3 3 3 0 TnsA endonuclease N terminal TPR_12 PF13424.1 ETO36770.1 - 1.2e-22 79.6 2.7 2.3e-10 40.2 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO36770.1 - 9.1e-17 60.4 5.1 1.5e-08 34.1 0.6 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETO36770.1 - 6.2e-15 54.0 10.7 3.7e-06 26.3 0.2 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETO36770.1 - 7.3e-15 53.5 0.8 0.00018 21.0 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETO36770.1 - 1.8e-14 52.4 7.3 0.0005 19.7 0.0 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO36770.1 - 1.3e-10 40.2 14.4 0.0033 17.0 0.6 5.0 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETO36770.1 - 1.2e-08 34.8 1.1 0.016 15.6 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat MIT PF04212.13 ETO36770.1 - 3.2e-05 23.7 4.8 0.058 13.2 0.1 4.2 3 1 0 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_16 PF13432.1 ETO36770.1 - 0.0063 17.1 0.0 2.3 8.9 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat Sel1 PF08238.7 ETO36770.1 - 0.03 14.9 2.1 8.7 7.1 0.0 3.4 3 0 0 3 3 3 0 Sel1 repeat TPR_10 PF13374.1 ETO36770.1 - 0.036 14.0 0.0 1.7 8.6 0.0 3.4 3 1 2 5 5 5 0 Tetratricopeptide repeat Kelch_6 PF13964.1 ETO36770.1 - 0.11 12.6 0.2 0.37 11.0 0.2 1.8 1 0 0 1 1 1 0 Kelch motif Apc3 PF12895.2 ETO36770.1 - 0.36 11.0 6.5 0.96 9.6 2.7 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Ank_2 PF12796.2 ETO36771.1 - 0.012 15.9 0.0 0.34 11.2 0.0 2.4 1 1 1 2 2 1 0 Ankyrin repeats (3 copies) Ank PF00023.25 ETO36771.1 - 0.12 12.2 0.0 5.2 7.0 0.0 2.7 2 1 0 2 2 2 0 Ankyrin repeat WD40 PF00400.27 ETO36772.1 - 4.1e-64 210.3 28.3 7.7e-11 41.4 0.9 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO36772.1 - 4.2e-11 41.6 9.3 0.002 16.3 0.1 5.6 1 1 3 5 5 5 5 Nucleoporin Nup120/160 DUF851 PF05867.6 ETO36772.1 - 0.044 13.0 0.0 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF851) U-box PF04564.10 ETO36773.1 - 1.2e-12 47.6 0.0 7.9e-12 44.9 0.0 1.9 1 1 0 1 1 1 1 U-box domain HJURP_C PF12347.3 ETO36774.1 - 0.16 11.5 0.4 0.31 10.6 0.3 1.4 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat WD40 PF00400.27 ETO36775.1 - 4.4e-05 23.1 2.7 0.089 12.7 0.0 4.3 4 1 1 5 5 5 2 WD domain, G-beta repeat Ribosomal_L33 PF00471.15 ETO36776.1 - 0.071 13.3 0.4 0.13 12.5 0.3 1.4 1 0 0 1 1 1 0 Ribosomal protein L33 Ank_2 PF12796.2 ETO36777.1 - 0.0098 16.2 0.1 0.021 15.1 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Mg_trans_NIPA PF05653.9 ETO36778.1 - 0.024 13.6 0.6 0.03 13.2 0.4 1.1 1 0 0 1 1 1 0 Magnesium transporter NIPA WD40 PF00400.27 ETO36779.1 - 9e-64 209.2 19.5 1.9e-10 40.2 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO36779.1 - 1.9e-11 42.8 3.8 0.24 9.4 0.0 5.7 2 1 4 6 6 6 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO36779.1 - 2e-05 23.5 11.2 0.091 11.4 0.8 3.4 1 1 1 3 3 3 3 Nup133 N terminal like Baculo_19 PF04798.7 ETO36779.1 - 0.037 13.3 1.3 0.54 9.6 0.6 2.5 2 0 0 2 2 2 0 Baculovirus 19 kDa protein conserved region SUKH_5 PF14567.1 ETO36779.1 - 0.64 9.4 3.0 4.7 6.6 0.0 3.4 3 1 1 5 5 5 0 SMI1-KNR4 cell-wall TPR_12 PF13424.1 ETO36780.1 - 2.5e-58 193.9 12.0 2.4e-20 72.2 0.5 3.6 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETO36780.1 - 4.6e-29 99.8 11.6 5.6e-11 41.9 0.1 3.5 3 0 0 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETO36780.1 - 1.7e-26 90.7 22.3 2.8e-07 29.8 0.1 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETO36780.1 - 1.4e-22 77.7 16.3 6.2e-06 25.7 0.1 5.7 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETO36780.1 - 1.9e-22 78.4 0.0 1e-06 28.4 0.1 5.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETO36780.1 - 2.4e-21 73.7 0.5 0.00048 19.7 0.0 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETO36780.1 - 1.5e-17 61.9 21.3 0.00015 21.2 0.5 5.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETO36780.1 - 1.8e-07 30.7 2.4 0.015 15.4 0.2 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETO36780.1 - 1.3e-06 28.5 1.3 6 7.5 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat MIT PF04212.13 ETO36780.1 - 1.8e-05 24.5 11.6 0.055 13.3 0.1 5.1 5 0 0 5 5 5 2 MIT (microtubule interacting and transport) domain TPR_14 PF13428.1 ETO36780.1 - 2.2e-05 24.6 0.0 3.3 8.6 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO36780.1 - 5e-05 23.8 0.0 0.5 11.1 0.0 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETO36780.1 - 0.0018 17.4 0.0 0.9 8.8 0.0 3.4 3 0 0 3 3 3 1 SHNi-TPR Apc3 PF12895.2 ETO36780.1 - 0.057 13.5 9.1 1.7 8.8 1.0 3.7 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 ETO36781.1 - 1.4e-31 108.2 0.4 7.7e-20 70.6 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO36781.1 - 3.9e-14 51.5 7.6 2e-07 30.3 0.3 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETO36781.1 - 1.8e-13 49.9 0.0 1.4e-06 28.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETO36781.1 - 2.5e-12 46.2 1.2 2e-07 30.5 0.5 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 ETO36781.1 - 6.2e-11 41.3 4.4 2e-05 24.1 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETO36781.1 - 3.2e-10 39.0 0.1 7.8e-05 22.1 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO36781.1 - 2.2e-05 23.9 4.3 0.083 12.7 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat MIT PF04212.13 ETO36781.1 - 0.00017 21.3 2.7 0.24 11.3 0.0 3.3 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_16 PF13432.1 ETO36781.1 - 0.00095 19.7 0.0 0.27 11.9 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETO36781.1 - 0.0092 16.1 0.1 0.52 10.6 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETO36781.1 - 0.015 15.7 0.1 2.2 8.9 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.7 ETO36781.1 - 0.027 14.2 1.2 0.59 9.9 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat GcpE PF04551.9 ETO36781.1 - 0.046 12.5 2.0 0.41 9.3 0.1 2.2 2 0 0 2 2 2 0 GcpE protein TPR_14 PF13428.1 ETO36781.1 - 0.06 14.0 0.0 3.6 8.4 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DWNN PF08783.6 ETO36781.1 - 3.3 7.7 6.1 1.4 8.9 2.1 2.0 2 0 0 2 2 1 0 DWNN domain KH_2 PF07650.12 ETO36782.1 - 0.076 12.5 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 KH domain SPRY PF00622.23 ETO36783.1 - 4e-05 23.6 0.2 6.4e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 SPRY domain DUF1149 PF06619.6 ETO36783.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1149) Kelch_2 PF07646.10 ETO36784.1 - 1.5e-07 30.8 4.2 0.095 12.5 0.1 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.1 ETO36784.1 - 3.2e-06 26.9 6.5 0.23 11.4 0.2 5.2 6 0 0 6 6 6 2 Kelch motif Kelch_6 PF13964.1 ETO36784.1 - 1.1e-05 25.3 4.5 0.52 10.5 0.1 4.6 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETO36784.1 - 2.7e-05 23.6 4.5 0.016 14.7 0.2 4.3 4 0 0 4 4 4 1 Kelch motif EHN PF06441.7 ETO36784.1 - 0.015 15.2 0.6 0.34 10.8 0.0 2.2 2 0 0 2 2 2 0 Epoxide hydrolase N terminus Kelch_4 PF13418.1 ETO36784.1 - 0.036 13.8 3.1 4.8 7.0 0.0 3.8 3 1 1 4 4 4 0 Galactose oxidase, central domain PUB PF09409.5 ETO36785.1 - 0.00016 21.3 0.8 0.0021 17.7 0.5 2.5 1 1 0 1 1 1 1 PUB domain DnaG_DnaB_bind PF08278.6 ETO36785.1 - 0.034 14.3 0.8 0.056 13.6 0.5 1.3 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding CUE PF02845.11 ETO36785.1 - 0.049 13.1 0.0 0.049 13.1 0.0 2.0 2 0 0 2 2 2 0 CUE domain AAA_24 PF13479.1 ETO36785.1 - 0.17 11.4 2.2 0.97 8.9 1.6 2.1 1 1 0 1 1 1 0 AAA domain LPP PF04728.8 ETO36786.1 - 0.077 12.8 1.4 1.2 8.9 0.0 3.0 3 0 0 3 3 3 0 Lipoprotein leucine-zipper YjgP_YjgQ PF03739.9 ETO36786.1 - 0.48 9.1 7.3 12 4.5 5.1 2.2 1 1 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF1664 PF07889.7 ETO36786.1 - 4.6 7.0 9.8 5.9 6.7 3.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) LIM PF00412.17 ETO36787.1 - 1.1e-07 31.7 5.8 1.1e-07 31.7 4.0 2.4 2 0 0 2 2 2 1 LIM domain Zn_ribbon_2 PF12674.2 ETO36787.1 - 0.0022 18.3 4.5 0.18 12.1 0.4 2.7 2 0 0 2 2 2 2 Putative zinc ribbon domain DivIC PF04977.10 ETO36787.1 - 0.0081 15.6 5.5 0.4 10.2 0.4 2.9 2 0 0 2 2 2 2 Septum formation initiator RILP PF11461.3 ETO36787.1 - 0.0099 16.0 0.4 0.0099 16.0 0.3 2.2 2 0 0 2 2 2 1 Rab interacting lysosomal protein zf-like PF04071.7 ETO36787.1 - 0.028 14.0 0.5 0.028 14.0 0.3 2.9 2 1 1 3 3 3 0 Cysteine-rich small domain IncA PF04156.9 ETO36787.1 - 0.35 10.4 5.0 0.86 9.1 0.6 2.2 2 0 0 2 2 2 0 IncA protein DZR PF12773.2 ETO36787.1 - 0.67 9.8 7.1 0.77 9.6 1.5 2.9 1 1 2 3 3 3 0 Double zinc ribbon Rieske PF00355.21 ETO36788.1 - 1.5e-14 53.3 0.5 2.4e-14 52.6 0.3 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.9 ETO36788.1 - 9.5e-05 22.5 0.1 0.00027 21.0 0.0 1.8 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region SMN PF06003.7 ETO36789.1 - 3.9e-08 32.7 14.5 1.9e-05 23.9 7.6 2.5 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) Ycf1 PF05758.7 ETO36789.1 - 0.24 9.0 6.9 0.3 8.7 4.8 1.0 1 0 0 1 1 1 0 Ycf1 Lin-8 PF03353.10 ETO36789.1 - 1.9 7.6 9.2 2.5 7.2 6.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist V-ATPase_H_N PF03224.9 ETO36790.1 - 0.01 15.0 0.2 0.011 14.9 0.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit H HMA PF00403.21 ETO36791.1 - 0.058 13.5 0.1 0.089 12.9 0.1 1.3 1 0 0 1 1 1 0 Heavy-metal-associated domain DUF2024 PF09630.5 ETO36791.1 - 0.079 12.6 0.1 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) Sulfatase PF00884.18 ETO36792.1 - 1.7e-33 116.1 0.0 2e-33 115.8 0.0 1.0 1 0 0 1 1 1 1 Sulfatase CAP_GLY PF01302.20 ETO36793.1 - 1.1e-33 114.7 3.0 7e-18 64.1 0.1 2.3 2 0 0 2 2 2 2 CAP-Gly domain ORC6 PF05460.8 ETO36793.1 - 0.013 14.6 5.8 0.019 14.1 4.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Hid1 PF12722.2 ETO36793.1 - 2.8 5.4 7.7 3.3 5.2 5.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nop14 PF04147.7 ETO36793.1 - 5 4.9 21.9 7.5 4.3 15.2 1.2 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 ETO36793.1 - 5.7 6.2 16.6 13 5.0 11.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) BUD22 PF09073.5 ETO36793.1 - 6.7 5.6 22.7 1.2 8.1 12.6 1.7 2 0 0 2 2 2 0 BUD22 SAM_1 PF00536.25 ETO36794.1 - 1.5e-06 28.2 0.1 2.8e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO36794.1 - 8.7e-06 25.4 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Herpes_LMP2 PF07415.6 ETO36794.1 - 5.8 5.3 5.4 9.4 4.6 3.7 1.3 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein RasGEF PF00617.14 ETO36795.1 - 2e-48 164.6 2.9 4.5e-48 163.4 2.0 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 ETO36795.1 - 6.3e-12 45.5 0.1 3.3e-11 43.2 0.1 2.2 1 0 0 1 1 1 1 RasGEF N-terminal motif ubiquitin PF00240.18 ETO36797.1 - 1.2e-06 27.7 0.1 1.2e-06 27.7 0.1 2.2 2 0 0 2 2 2 1 Ubiquitin family SPX PF03105.14 ETO36797.1 - 0.019 14.7 7.4 0.027 14.2 5.1 1.1 1 0 0 1 1 1 0 SPX domain Allantoicase PF03561.10 ETO36797.1 - 0.2 11.1 4.9 2 7.8 1.7 3.0 2 1 0 2 2 2 0 Allantoicase repeat EssA PF10661.4 ETO36798.1 - 0.14 11.8 1.3 0.24 11.0 0.9 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA WD40 PF00400.27 ETO36799.1 - 6.3e-08 32.2 1.1 0.0034 17.2 0.6 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO36799.1 - 0.052 11.6 0.1 0.054 11.6 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Hydrolase_3 PF08282.7 ETO36800.1 - 0.6 9.6 3.4 0.72 9.3 0.9 1.8 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Pox_D3 PF04580.8 ETO36801.1 - 0.059 12.5 0.0 0.063 12.4 0.0 1.1 1 0 0 1 1 1 0 Chordopoxvirinae D3 protein Copper-bind PF00127.15 ETO36801.1 - 0.12 12.5 0.2 0.2 11.9 0.1 1.5 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family RNase_H PF00075.19 ETO36802.1 - 9.4e-08 32.4 0.0 1.3e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 ETO36802.1 - 0.026 14.3 0.1 0.059 13.1 0.0 1.6 1 1 0 1 1 1 0 Reverse transcriptase-like Aldo_ket_red PF00248.16 ETO36803.1 - 7.2e-57 192.3 0.0 3.8e-55 186.7 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family DUF445 PF04286.7 ETO36804.1 - 0.057 12.9 1.0 0.072 12.6 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) UQ_con PF00179.21 ETO36805.1 - 5e-25 87.5 0.0 6.9e-25 87.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 ETO36805.1 - 0.0086 15.9 0.1 0.024 14.5 0.0 1.9 2 0 0 2 2 2 1 RWD domain DSBA PF01323.15 ETO36806.1 - 5e-34 117.5 0.0 6.3e-24 84.6 0.0 2.1 2 0 0 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 ETO36806.1 - 0.0093 15.9 0.1 1.2 9.0 0.0 2.9 3 0 0 3 3 3 1 Thioredoxin SGT1 PF07093.6 ETO36807.1 - 1.6e-51 175.4 53.9 5.9e-46 157.0 13.4 2.8 1 1 1 2 2 2 2 SGT1 protein zf-TRAF PF02176.13 ETO36808.1 - 4.7e-14 52.5 20.6 1.5e-08 34.8 5.9 6.3 4 2 2 6 6 6 4 TRAF-type zinc finger zf-C3HC4 PF00097.20 ETO36808.1 - 1.2e-08 34.4 14.5 1.2e-08 34.4 10.0 5.2 5 1 2 7 7 7 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETO36808.1 - 1.3e-07 31.2 13.2 1.3e-07 31.2 9.2 4.6 4 1 1 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO36808.1 - 6.7e-07 29.2 13.6 6.7e-07 29.2 9.4 6.2 4 1 2 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO36808.1 - 1.1e-06 28.2 11.5 1.1e-06 28.2 8.0 6.6 5 2 2 7 7 7 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 ETO36808.1 - 4.6e-06 26.3 5.8 2.1e-05 24.2 4.0 2.1 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 ETO36808.1 - 0.0046 16.6 13.2 0.0046 16.6 9.2 6.0 6 1 0 7 7 7 1 zinc-RING finger domain zf-RING_4 PF14570.1 ETO36808.1 - 0.013 15.0 9.5 0.013 15.0 6.6 5.8 5 2 1 6 6 6 0 RING/Ubox like zinc-binding domain PhnA_Zn_Ribbon PF08274.7 ETO36808.1 - 0.28 10.9 12.5 1.4 8.7 1.2 3.9 3 0 0 3 3 3 0 PhnA Zinc-Ribbon DUF572 PF04502.8 ETO36809.1 - 0.0097 15.1 13.0 0.011 15.0 9.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) SWI-SNF_Ssr4 PF08549.5 ETO36809.1 - 0.13 10.5 7.4 0.16 10.2 4.8 1.3 1 1 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Daxx PF03344.10 ETO36809.1 - 0.2 10.0 14.9 0.21 10.0 10.4 1.1 1 0 0 1 1 1 0 Daxx Family SAPS PF04499.10 ETO36809.1 - 0.25 9.9 9.9 0.26 9.8 6.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Peptidase_S64 PF08192.6 ETO36809.1 - 0.45 8.7 13.1 0.5 8.6 9.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 DNA_pol_viral_N PF00242.12 ETO36809.1 - 0.56 9.1 11.3 0.7 8.8 7.9 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Tim54 PF11711.3 ETO36809.1 - 1.3 7.5 9.1 1.6 7.2 6.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2052 PF09747.4 ETO36809.1 - 1.6 8.5 16.9 2.6 7.9 11.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Hid1 PF12722.2 ETO36809.1 - 1.7 6.2 13.6 1.6 6.2 9.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Vfa1 PF08432.5 ETO36809.1 - 2.7 7.9 18.5 4.3 7.3 12.8 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1510 PF07423.6 ETO36809.1 - 2.7 7.2 20.4 3.8 6.8 14.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) BNIP2 PF12496.3 ETO36809.1 - 4.3 7.5 11.9 8 6.6 8.2 1.4 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Ndc1_Nup PF09531.5 ETO36809.1 - 4.6 5.5 9.5 5.6 5.2 6.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOBP PF15279.1 ETO36809.1 - 5.6 7.2 11.2 6.5 7.0 7.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein TEX19 PF15553.1 ETO36809.1 - 8.1 6.2 7.6 14 5.4 5.3 1.5 1 0 0 1 1 1 0 Testis-expressed protein 19 Neur_chan_memb PF02932.11 ETO36809.1 - 9.9 5.9 11.9 14 5.4 8.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EF-hand_6 PF13405.1 ETO36810.1 - 6.5e-06 25.6 9.8 0.00032 20.3 0.2 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 ETO36810.1 - 1.6e-05 24.9 4.3 3e-05 24.0 1.4 2.6 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 ETO36810.1 - 0.00021 20.3 3.9 0.0049 16.0 0.6 3.5 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.1 ETO36810.1 - 0.00039 19.6 4.8 0.0016 17.6 0.3 3.4 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 ETO36810.1 - 0.00042 19.8 0.4 0.00042 19.8 0.3 2.7 1 1 1 2 2 2 2 EF-hand domain pair YcxB PF14317.1 ETO36810.1 - 0.019 14.2 0.2 0.07 12.3 0.0 2.0 2 0 0 2 2 2 0 YcxB-like protein FISNA PF14484.1 ETO36811.1 - 0.15 12.0 2.6 0.41 10.6 1.8 1.8 1 0 0 1 1 1 0 Fish-specific NACHT associated domain SAP PF02037.22 ETO36812.1 - 2.4e-08 33.2 0.9 3.5e-08 32.7 0.1 1.7 2 0 0 2 2 2 1 SAP domain VWA_2 PF13519.1 ETO36812.1 - 0.00016 21.8 0.0 0.00023 21.3 0.0 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain PADR1 PF08063.7 ETO36812.1 - 0.00032 20.0 4.2 0.0013 18.1 2.9 2.1 1 1 0 1 1 1 1 PADR1 (NUC008) domain DNA_gyraseB PF00204.20 ETO36812.1 - 0.0088 15.2 0.1 0.022 13.9 0.0 1.7 1 0 0 1 1 1 1 DNA gyrase B THF_DHG_CYH PF00763.18 ETO36812.1 - 0.034 14.1 0.9 0.057 13.4 0.1 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain TORC_M PF12885.2 ETO36812.1 - 0.06 13.1 0.2 0.19 11.5 0.0 1.7 1 1 1 2 2 2 0 Transducer of regulated CREB activity middle domain Telomere_Sde2_2 PF13297.1 ETO36812.1 - 0.092 12.0 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 Telomere stability C-terminal TcdB_N PF12918.2 ETO36812.1 - 0.4 10.7 5.3 2.4 8.2 0.1 2.5 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain RVT_1 PF00078.22 ETO36813.1 - 6.6e-06 25.6 0.0 8.1e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CENP-R PF06729.7 ETO36813.1 - 1.5 8.4 4.5 1.9 8.1 0.1 2.2 2 1 0 2 2 2 0 Kinetochore component, CENP-R WD40 PF00400.27 ETO36817.1 - 6.9e-09 35.2 0.1 6.7e-08 32.1 0.0 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF762 PF05555.6 ETO36817.1 - 0.028 13.6 0.6 0.029 13.6 0.4 1.1 1 0 0 1 1 1 0 Coxiella burnetii protein of unknown function (DUF762) UPF0180 PF03698.8 ETO36818.1 - 0.0052 16.5 0.9 1 9.2 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0180) HGTP_anticodon PF03129.15 ETO36818.1 - 0.048 13.5 0.3 0.071 13.0 0.2 1.3 1 0 0 1 1 1 0 Anticodon binding domain RNase_H PF00075.19 ETO36819.1 - 4.8e-06 26.9 0.0 0.031 14.6 0.0 2.1 1 1 1 2 2 2 2 RNase H DUF4220 PF13968.1 ETO36820.1 - 0.13 11.2 1.6 0.14 11.1 1.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Mitofilin PF09731.4 ETO36822.1 - 1.7 7.2 19.6 1.8 7.1 13.6 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Bap31 PF05529.7 ETO36822.1 - 2.5 7.5 14.8 4.3 6.7 10.3 1.4 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like FNIP_N PF14636.1 ETO36822.1 - 4.5 7.7 12.4 0.98 9.8 6.6 1.3 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus DUF3807 PF12720.2 ETO36822.1 - 6.1 6.9 17.7 7.2 6.7 12.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Pkinase PF00069.20 ETO36824.1 - 3.3e-06 26.4 0.2 3.3e-06 26.4 0.1 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO36824.1 - 0.0055 15.8 0.1 0.0055 15.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase NMDAR2_C PF10565.4 ETO36824.1 - 0.018 13.7 8.4 0.021 13.4 5.8 1.1 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus ABC1 PF03109.11 ETO36824.1 - 0.062 13.2 2.3 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 ABC1 family DUF1501 PF07394.7 ETO36824.1 - 0.17 10.6 5.1 0.18 10.6 3.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF3513 PF12026.3 ETO36824.1 - 0.26 10.8 8.5 0.31 10.5 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) TFIIA PF03153.8 ETO36824.1 - 0.26 11.1 14.7 0.28 11.0 10.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AIP3 PF03915.8 ETO36824.1 - 0.79 8.5 9.6 0.9 8.3 6.7 1.0 1 0 0 1 1 1 0 Actin interacting protein 3 Spore_coat_CotO PF14153.1 ETO36824.1 - 0.85 9.0 12.8 0.92 8.9 8.8 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF2072 PF09845.4 ETO36824.1 - 1.3 8.9 7.5 2.4 8.1 5.2 1.6 1 1 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) RP-C_C PF11800.3 ETO36824.1 - 1.8 8.2 8.5 2.2 7.9 5.9 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region PIH1 PF08190.7 ETO36824.1 - 2.3 7.5 14.0 2.3 7.5 9.7 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Plasmodium_Vir PF05795.6 ETO36824.1 - 3.6 6.7 14.3 4 6.5 9.9 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Hid1 PF12722.2 ETO36824.1 - 4.5 4.8 15.1 4.6 4.7 10.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2146 PF10220.4 ETO36824.1 - 4.7 5.0 10.7 4.8 5.0 7.4 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Neur_chan_memb PF02932.11 ETO36824.1 - 4.9 6.9 10.5 4.8 6.9 7.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM60A PF15396.1 ETO36824.1 - 5.1 6.7 10.1 6.2 6.5 7.0 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Dicty_REP PF05086.7 ETO36824.1 - 5.2 4.6 17.0 5.3 4.6 11.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4163 PF13739.1 ETO36824.1 - 6.1 7.6 14.2 6.4 7.6 9.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4163) PA26 PF04636.8 ETO36824.1 - 7.3 5.1 7.4 7.5 5.1 5.1 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Presenilin PF01080.12 ETO36824.1 - 8.4 5.0 11.9 9 5.0 8.2 1.1 1 0 0 1 1 1 0 Presenilin DHHW PF14286.1 ETO36824.1 - 9 5.5 13.1 9.5 5.4 9.1 1.0 1 0 0 1 1 1 0 DHHW protein Band_3_cyto PF07565.8 ETO36824.1 - 9.3 5.6 7.4 9.7 5.6 5.1 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4407 PF14362.1 ETO36824.1 - 9.9 5.0 7.5 9.6 5.0 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2052 PF09747.4 ETO36825.1 - 1.2e-07 31.7 8.8 0.0041 17.0 8.5 2.1 1 1 1 2 2 2 2 Coiled-coil domain containing protein (DUF2052) DUF3801 PF12687.2 ETO36825.1 - 8.7e-05 22.1 2.5 0.0001 21.9 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3801) GAGA_bind PF06217.7 ETO36825.1 - 0.00022 21.3 5.9 0.00027 21.0 4.1 1.1 1 0 0 1 1 1 1 GAGA binding protein-like family Adaptin_binding PF10199.4 ETO36825.1 - 0.00036 20.8 7.5 0.00055 20.2 5.2 1.4 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 DUF1510 PF07423.6 ETO36825.1 - 0.016 14.5 19.2 0.025 13.9 13.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Astro_capsid PF03115.9 ETO36825.1 - 0.02 13.2 4.3 0.022 13.0 3.0 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor PRTP PF01366.13 ETO36825.1 - 0.065 11.2 3.6 0.086 10.8 2.5 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Daxx PF03344.10 ETO36825.1 - 0.068 11.6 12.2 0.077 11.4 8.4 1.1 1 0 0 1 1 1 0 Daxx Family DUF2722 PF10846.3 ETO36825.1 - 0.08 11.9 11.0 0.098 11.6 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Tom22 PF04281.8 ETO36825.1 - 0.45 10.0 8.1 0.79 9.2 5.6 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 CDC45 PF02724.9 ETO36825.1 - 0.46 8.4 13.1 0.56 8.1 9.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Eapp_C PF10238.4 ETO36825.1 - 1.4 8.7 11.5 2.7 7.8 8.0 1.4 1 0 0 1 1 1 0 E2F-associated phosphoprotein Vfa1 PF08432.5 ETO36825.1 - 1.6 8.7 17.9 2.3 8.2 12.4 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 BTV_NS2 PF04514.7 ETO36825.1 - 3.6 6.3 14.3 4.8 5.9 9.9 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 AIF_C PF14721.1 ETO36825.1 - 3.9 7.7 8.3 7.8 6.7 5.8 1.5 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF3403 PF11883.3 ETO36826.1 - 0.07 13.4 1.3 5.6 7.3 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3403) ERp29 PF07749.7 ETO36827.1 - 0.034 14.7 0.2 0.038 14.6 0.2 1.2 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain DUF2046 PF09755.4 ETO36827.1 - 0.037 12.9 0.0 0.04 12.8 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) DUF61 PF01886.11 ETO36827.1 - 0.076 12.8 0.3 0.097 12.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF61 Daxx PF03344.10 ETO36828.1 - 0.23 9.8 7.5 0.27 9.6 5.2 1.0 1 0 0 1 1 1 0 Daxx Family SOBP PF15279.1 ETO36828.1 - 6.1 7.1 10.5 7.1 6.9 7.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein IncA PF04156.9 ETO36830.1 - 0.0048 16.5 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 IncA protein OTU PF02338.14 ETO36830.1 - 0.006 17.1 0.2 0.017 15.6 0.1 1.8 1 0 0 1 1 1 1 OTU-like cysteine protease ICA69 PF04629.9 ETO36830.1 - 0.1 12.5 0.3 0.14 12.0 0.2 1.3 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain LigT_PEase PF02834.11 ETO36830.1 - 0.13 12.2 0.1 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 LigT like Phosphoesterase bZIP_1 PF00170.16 ETO36830.1 - 0.59 10.1 6.5 0.85 9.6 1.4 2.9 2 0 0 2 2 2 0 bZIP transcription factor FliJ PF02050.11 ETO36831.1 - 0.01 15.8 2.3 0.01 15.8 1.6 5.8 5 2 1 6 6 6 0 Flagellar FliJ protein Nup54 PF13874.1 ETO36832.1 - 0.00037 20.1 9.2 0.0013 18.4 6.0 1.9 1 1 0 1 1 1 1 Nucleoporin complex subunit 54 IncA PF04156.9 ETO36832.1 - 0.00089 18.9 13.8 0.0011 18.5 9.5 1.3 1 0 0 1 1 1 1 IncA protein TMF_DNA_bd PF12329.3 ETO36832.1 - 0.001 18.8 8.4 0.001 18.8 5.8 2.6 1 1 1 2 2 2 1 TATA element modulatory factor 1 DNA binding B3_4 PF03483.12 ETO36832.1 - 0.014 14.8 0.2 0.022 14.2 0.2 1.3 1 0 0 1 1 1 0 B3/4 domain BLOC1_2 PF10046.4 ETO36832.1 - 0.018 15.1 12.2 0.67 10.1 2.7 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6 PF04111.7 ETO36832.1 - 0.15 11.0 18.3 0.25 10.3 12.7 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 Reo_sigmaC PF04582.7 ETO36832.1 - 0.19 10.9 1.8 0.25 10.4 1.2 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF4254 PF14063.1 ETO36832.1 - 0.22 11.0 6.3 0.38 10.3 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4254) Lipase_chap PF03280.9 ETO36832.1 - 0.36 10.3 9.0 0.32 10.5 0.8 2.2 1 1 1 2 2 2 0 Proteobacterial lipase chaperone protein DUF479 PF04336.7 ETO36832.1 - 0.41 10.7 2.8 6.4 6.9 0.7 2.4 1 1 1 2 2 2 0 Protein of unknown function, DUF479 Mod_r PF07200.8 ETO36832.1 - 0.49 10.2 18.3 0.7 9.8 11.7 2.0 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF3715 PF12509.3 ETO36832.1 - 0.91 9.3 8.1 0.66 9.8 1.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3715) GAS PF13851.1 ETO36832.1 - 0.99 8.5 21.0 2.8 7.0 12.5 2.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding eIF-4B PF06273.6 ETO36832.1 - 1.4 7.5 10.0 5 5.7 6.9 1.8 1 1 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Tropomyosin_1 PF12718.2 ETO36832.1 - 1.8 8.3 25.5 0.34 10.7 5.6 2.6 2 1 1 3 3 3 0 Tropomyosin like MerR-DNA-bind PF09278.6 ETO36832.1 - 2.8 8.4 6.4 3.5 8.0 1.7 2.5 2 0 0 2 2 2 0 MerR, DNA binding V_ATPase_I PF01496.14 ETO36832.1 - 3.9 5.1 9.2 5.6 4.6 6.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4140 PF13600.1 ETO36832.1 - 5 7.6 12.5 9 6.8 1.9 2.4 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Med30 PF11315.3 ETO36832.1 - 5.3 7.1 9.5 1.6 8.8 2.6 2.3 1 1 1 2 2 2 0 Mediator complex subunit 30 NPV_P10 PF05531.7 ETO36832.1 - 7.6 6.8 6.3 41 4.5 3.7 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Pkinase PF00069.20 ETO36833.1 - 7.5e-63 212.1 1.5 4.8e-62 209.4 1.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO36833.1 - 5e-35 120.8 0.4 9e-35 119.9 0.2 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETO36833.1 - 1.5e-05 24.1 0.0 2.6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETO36833.1 - 0.0032 16.5 0.1 0.0079 15.2 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PH_11 PF15413.1 ETO36833.1 - 0.016 15.4 0.8 0.095 12.9 0.0 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain YrbL-PhoP_reg PF10707.4 ETO36833.1 - 0.026 13.8 1.2 0.16 11.2 0.0 2.4 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL PH PF00169.24 ETO36833.1 - 0.36 11.0 9.8 0.075 13.2 3.3 2.6 2 1 0 2 2 2 0 PH domain PhyH PF05721.8 ETO36834.1 - 3.8e-10 40.1 0.0 6.3e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Hydrolase_6 PF13344.1 ETO36834.1 - 0.081 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase AA_permease PF00324.16 ETO36835.1 - 9.2e-16 57.2 10.2 1.2e-15 56.8 7.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETO36835.1 - 1.1e-06 27.4 9.5 1.5e-06 27.0 6.6 1.1 1 0 0 1 1 1 1 Amino acid permease Alpha-amylase_N PF02903.9 ETO36835.1 - 0.071 13.0 0.2 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Alpha amylase, N-terminal ig-like domain ATG22 PF11700.3 ETO36835.1 - 0.076 11.4 4.6 0.12 10.7 3.2 1.3 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Laminin_G_3 PF13385.1 ETO36837.1 - 2e-10 41.1 0.1 2.8e-10 40.6 0.1 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4231 PF14015.1 ETO36837.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Phosphodiest PF01663.17 ETO36838.1 - 1e-28 100.7 0.1 1.3e-28 100.4 0.1 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 ETO36838.1 - 4.4e-06 26.2 0.0 6.4e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 ETO36838.1 - 0.0077 15.4 0.1 0.014 14.6 0.1 1.5 1 1 0 1 1 1 1 Sulfatase DUF229 PF02995.12 ETO36838.1 - 0.096 11.0 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) GILT PF03227.11 ETO36840.1 - 1.6e-19 69.7 1.1 3e-19 68.8 0.6 1.6 1 1 1 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) DdrB PF12747.2 ETO36840.1 - 0.079 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 DdrB-like protein Pkinase PF00069.20 ETO36841.1 - 8.6e-11 41.4 0.0 1.4e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO36841.1 - 0.047 12.7 0.0 0.074 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase TPR_8 PF13181.1 ETO36842.1 - 0.044 13.5 0.1 0.087 12.6 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat CheR PF01739.13 ETO36842.1 - 0.083 12.1 0.3 0.092 12.0 0.2 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Dynein_light PF01221.13 ETO36844.1 - 0.025 14.5 0.1 0.087 12.8 0.0 1.9 1 0 0 1 1 1 0 Dynein light chain type 1 Cys_Met_Meta_PP PF01053.15 ETO36845.1 - 4.4e-146 486.1 0.0 5e-146 485.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 ETO36845.1 - 4.7e-09 35.6 0.0 6.7e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 ETO36845.1 - 1.6e-08 33.7 0.0 7.8e-07 28.1 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class-V HMG_box PF00505.14 ETO36846.1 - 0.00084 19.5 4.4 0.00084 19.5 3.0 2.6 3 0 0 3 3 3 1 HMG (high mobility group) box DUF247 PF03140.10 ETO36846.1 - 0.095 11.6 1.5 0.11 11.4 1.0 1.0 1 0 0 1 1 1 0 Plant protein of unknown function DUF755 PF05501.6 ETO36846.1 - 0.14 12.2 12.4 0.18 11.8 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) TRH PF05438.7 ETO36846.1 - 0.52 9.6 8.3 0.66 9.3 5.7 1.2 1 0 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) RasGEF_N PF00618.15 ETO36847.1 - 0.15 12.2 4.0 0.34 11.0 2.8 1.6 1 1 1 2 2 2 0 RasGEF N-terminal motif Tubulin PF00091.20 ETO36848.1 - 4e-32 111.7 0.1 5e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Gly_kinase PF02595.10 ETO36848.1 - 0.012 14.3 0.0 0.014 14.1 0.0 1.1 1 0 0 1 1 1 0 Glycerate kinase family Tubulin_2 PF13809.1 ETO36848.1 - 0.027 13.4 0.1 0.068 12.0 0.0 1.7 1 1 1 2 2 2 0 Tubulin like PCRF PF03462.13 ETO36848.1 - 0.06 13.0 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 PCRF domain Lsm_C PF14894.1 ETO36848.1 - 0.1 12.1 0.1 0.43 10.1 0.0 2.1 2 0 0 2 2 2 0 Lsm C-terminal DUF1874 PF08960.5 ETO36849.1 - 0.096 12.4 0.5 0.15 11.8 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1874) BBE PF08031.7 ETO36849.1 - 0.11 12.4 1.0 0.18 11.7 0.7 1.4 1 0 0 1 1 1 0 Berberine and berberine like WD40 PF00400.27 ETO36851.1 - 6.4e-25 86.0 2.0 4.9e-12 45.2 0.0 3.8 3 1 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETO36851.1 - 0.014 13.5 0.0 0.037 12.1 0.0 1.6 1 1 0 1 1 1 0 Nucleoporin Nup120/160 WD40 PF00400.27 ETO36852.1 - 3.9e-44 147.0 3.4 1.9e-08 33.8 0.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETO36852.1 - 1.7e-08 34.3 0.0 0.0023 17.6 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETO36852.1 - 8.3e-06 24.2 0.0 0.039 12.0 0.0 3.6 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO36852.1 - 0.013 13.7 0.0 1.3 7.2 0.0 2.7 1 1 2 3 3 3 0 Cytochrome D1 heme domain Mid2 PF04478.7 ETO36852.1 - 0.04 13.3 0.2 0.27 10.6 0.1 2.2 2 1 0 2 2 2 0 Mid2 like cell wall stress sensor Nbas_N PF15492.1 ETO36852.1 - 0.069 12.2 0.2 7.8 5.5 0.1 2.8 1 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal PLD_C PF12357.3 ETO36852.1 - 0.077 12.5 0.2 34 4.0 0.0 3.5 3 1 0 3 3 3 0 Phospholipase D C terminal Proteasome_A_N PF10584.4 ETO36852.1 - 1.4 8.2 4.1 26 4.2 0.0 3.7 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 ETO36855.1 - 2.1e-15 55.8 8.2 2.1e-08 33.6 1.0 3.8 3 1 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO36855.1 - 0.0026 15.9 0.1 0.69 7.9 0.0 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Zea_mays_MuDR PF05928.6 ETO36855.1 - 0.053 12.9 0.1 0.065 12.6 0.1 1.1 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) WD40 PF00400.27 ETO36856.1 - 9.4e-73 237.7 22.3 5.1e-13 48.3 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO36856.1 - 4.2e-07 28.5 7.3 0.012 13.7 0.0 4.3 1 1 3 5 5 5 3 Nucleoporin Nup120/160 Nbas_N PF15492.1 ETO36856.1 - 4.8e-06 25.8 2.5 0.65 9.0 0.0 4.4 1 1 3 5 5 5 3 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 ETO36856.1 - 3.5e-05 22.2 2.0 0.091 11.0 0.1 3.5 2 1 2 4 4 4 3 Cytochrome D1 heme domain PD40 PF07676.7 ETO36856.1 - 6.9e-05 22.4 4.7 2 8.1 0.1 4.7 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 ETO36856.1 - 0.00019 20.9 0.2 0.0074 15.7 0.1 2.9 1 1 0 1 1 1 1 PQQ-like domain Nucleoporin_N PF08801.6 ETO36856.1 - 0.00024 20.0 8.8 0.72 8.5 0.1 4.3 1 1 3 4 4 4 2 Nup133 N terminal like PQQ PF01011.16 ETO36856.1 - 0.0008 18.8 0.0 1.2 8.7 0.0 4.5 5 0 0 5 5 5 1 PQQ enzyme repeat Coatomer_WDAD PF04053.9 ETO36856.1 - 0.0031 16.3 0.1 0.011 14.6 0.0 1.9 1 1 1 2 2 2 1 Coatomer WD associated region Ricin_B_lectin PF00652.17 ETO36856.1 - 0.024 14.6 0.2 0.76 9.8 0.0 2.6 2 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain PT PF04886.7 ETO36857.1 - 1.8e-12 46.3 81.4 4.5e-05 22.6 2.9 6.4 1 1 4 5 5 5 4 PT repeat DUF4101 PF13355.1 ETO36858.1 - 0.018 15.4 0.2 0.084 13.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4101) SpoIIIAH PF12685.2 ETO36858.1 - 0.05 13.0 1.5 0.082 12.3 1.0 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein MCR_D PF02505.9 ETO36858.1 - 0.11 12.0 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein D DUF2962 PF11176.3 ETO36859.1 - 0.71 9.4 5.6 0.19 11.3 1.9 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2962) MotB_plug PF13677.1 ETO36859.1 - 8.5 5.7 9.5 2.3 7.6 0.1 3.1 3 0 0 3 3 3 0 Membrane MotB of proton-channel complex MotA/MotB WD40 PF00400.27 ETO36861.1 - 5.6e-56 184.5 27.2 7.7e-11 41.4 0.1 7.4 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO36861.1 - 1e-07 30.5 3.7 0.058 11.5 0.1 5.0 2 2 3 5 5 5 5 Nucleoporin Nup120/160 Thioredoxin_8 PF13905.1 ETO36863.1 - 7.6 6.7 9.2 0.46 10.6 0.4 3.2 3 2 0 3 3 3 0 Thioredoxin-like TSC22 PF01166.13 ETO36864.1 - 0.73 9.8 3.9 3.8 7.5 0.6 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family RGS PF00615.14 ETO36865.1 - 6.1e-05 23.1 0.2 8.1e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain ORC4_C PF14629.1 ETO36866.1 - 3.2e-08 33.1 1.6 2.8e-07 30.1 0.1 2.3 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 ETO36866.1 - 5.8e-08 32.9 0.0 1.6e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.9 ETO36866.1 - 0.00054 19.0 0.0 0.0013 17.7 0.0 1.6 1 0 0 1 1 1 1 KAP family P-loop domain DUF815 PF05673.8 ETO36866.1 - 0.00067 18.6 0.1 0.0012 17.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 ETO36866.1 - 0.0011 19.0 0.0 0.003 17.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 ETO36866.1 - 0.0035 17.6 0.0 0.012 15.9 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA PF00004.24 ETO36866.1 - 0.0095 16.1 0.0 0.081 13.1 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 ETO36866.1 - 0.016 14.4 0.0 0.036 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 ETO36866.1 - 0.069 12.8 1.0 0.27 10.8 0.2 2.5 2 1 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 ETO36866.1 - 0.074 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.1 ETO36866.1 - 0.13 11.7 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribosomal_L11_N PF03946.9 ETO36867.1 - 5.9e-15 54.4 0.0 1e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ras PF00071.17 ETO36868.1 - 1.1e-45 154.9 0.5 1.8e-45 154.2 0.3 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETO36868.1 - 9.8e-14 51.8 0.9 5.1e-12 46.3 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETO36868.1 - 7.8e-09 35.0 0.4 1e-08 34.6 0.3 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO36868.1 - 1e-06 28.3 0.4 1.7e-06 27.5 0.1 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Seipin PF06775.9 ETO36869.1 - 0.013 15.0 0.1 0.031 13.7 0.0 1.7 1 1 0 1 1 1 0 Putative adipose-regulatory protein (Seipin) F-box-like PF12937.2 ETO36869.1 - 0.11 12.2 0.8 0.53 10.0 0.6 2.2 1 1 0 1 1 1 0 F-box-like Acetyltransf_3 PF13302.1 ETO36869.1 - 0.11 12.6 0.1 10 6.2 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Laminin_II PF06009.7 ETO36870.1 - 0.0045 16.7 0.4 0.013 15.2 0.3 1.8 1 1 0 1 1 1 1 Laminin Domain II DUF2854 PF11016.3 ETO36870.1 - 0.033 13.7 0.4 0.049 13.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) DUF2775 PF10950.3 ETO36870.1 - 3.8 7.7 9.4 2.8 8.1 1.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2775) Skp1 PF01466.14 ETO36871.1 - 1.9e-18 66.2 0.1 3.9e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 ETO36871.1 - 8.5e-05 22.5 0.6 0.00066 19.7 0.0 2.5 3 0 0 3 3 3 1 Skp1 family, tetramerisation domain Cofilin_ADF PF00241.15 ETO36873.1 - 2.4e-05 24.1 0.0 3.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF3960 PF13142.1 ETO36874.1 - 0.098 12.4 0.3 0.13 12.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3960) WD40 PF00400.27 ETO36875.1 - 2.4e-83 271.3 8.5 4.9e-13 48.4 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETO36875.1 - 1.1e-07 30.3 6.6 1.4 6.9 0.0 5.5 1 1 4 5 5 5 4 Nucleoporin Nup120/160 PD40 PF07676.7 ETO36875.1 - 1.7e-05 24.3 6.1 17 5.2 0.1 6.4 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 ETO36875.1 - 0.00062 18.9 0.5 0.15 11.1 0.0 3.7 1 1 4 5 5 5 1 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 ETO36875.1 - 0.00076 19.0 1.3 0.1 12.0 0.9 2.8 1 1 0 1 1 1 1 PQQ-like domain DUF1258 PF06869.7 ETO36875.1 - 0.001 18.2 2.2 0.45 9.5 0.0 3.3 2 2 1 4 4 4 2 Protein of unknown function (DUF1258) Resistin PF06954.6 ETO36875.1 - 0.002 18.3 0.3 23 5.3 0.0 4.6 3 2 2 5 5 5 0 Resistin Cytochrom_D1 PF02239.11 ETO36875.1 - 0.026 12.8 0.1 1.1 7.4 0.0 2.7 1 1 2 3 3 3 0 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 ETO36875.1 - 0.11 11.8 1.5 66 2.9 0.0 4.4 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature SecA_DEAD PF07517.9 ETO36876.1 - 3.1e-10 39.7 0.0 2.1e-09 37.0 0.0 2.5 1 1 0 1 1 1 1 SecA DEAD-like domain Helicase_C PF00271.26 ETO36876.1 - 0.0055 16.5 0.0 0.022 14.6 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Scm3 PF10384.4 ETO36876.1 - 0.7 9.4 8.7 3.1 7.3 0.1 4.1 4 0 0 4 4 4 0 Centromere protein Scm3 CLASP_N PF12348.3 ETO36877.1 - 1e-06 28.2 0.1 0.13 11.5 0.0 3.9 4 1 0 4 4 4 2 CLASP N terminal HEAT_EZ PF13513.1 ETO36877.1 - 1.8e-06 28.2 1.3 0.26 11.8 0.0 5.6 6 0 0 6 6 6 1 HEAT-like repeat Cnd1 PF12717.2 ETO36877.1 - 0.00024 20.9 0.4 0.67 9.7 0.0 3.2 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.14 ETO36877.1 - 0.00077 19.3 0.0 0.0055 16.5 0.0 2.7 1 0 0 1 1 1 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 ETO36877.1 - 0.001 17.5 5.4 0.37 9.0 0.5 3.5 2 2 0 2 2 2 2 Adaptin N terminal region Xpo1 PF08389.7 ETO36877.1 - 0.0029 17.5 3.5 0.02 14.8 0.0 3.9 4 0 0 4 4 4 1 Exportin 1-like protein HEAT PF02985.17 ETO36877.1 - 0.084 13.0 10.3 25 5.3 0.1 7.2 7 0 0 7 7 7 0 HEAT repeat DUF3501 PF12007.3 ETO36877.1 - 0.11 12.2 0.5 1.9 8.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3501) GET2 PF08690.5 ETO36877.1 - 8.7 5.4 8.3 9.9 5.3 0.6 2.8 3 0 0 3 3 3 0 GET complex subunit GET2 zf-RING_2 PF13639.1 ETO36878.1 - 9.5e-13 47.7 7.7 2e-12 46.6 5.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO36878.1 - 1.6e-08 34.3 7.0 3.1e-08 33.5 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO36878.1 - 2.1e-07 30.5 4.0 4.3e-07 29.4 2.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETO36878.1 - 2.6e-07 30.6 8.2 9.4e-07 28.8 5.7 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 ETO36878.1 - 6.8e-07 28.9 5.8 1.1e-06 28.1 4.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 ETO36878.1 - 8.4e-07 28.5 5.9 1.5e-06 27.7 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 ETO36878.1 - 3.8e-05 23.4 2.4 8.9e-05 22.2 1.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 ETO36878.1 - 0.025 14.6 6.1 0.059 13.4 4.2 1.6 1 0 0 1 1 1 0 RING-variant domain zf-HC5HC2H PF13771.1 ETO36878.1 - 0.071 13.2 1.1 0.14 12.3 0.1 1.8 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-RING-like PF08746.6 ETO36878.1 - 0.071 13.1 1.6 0.15 12.0 1.1 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_UBOX PF13445.1 ETO36878.1 - 0.079 12.6 4.5 0.17 11.6 3.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-Nse PF11789.3 ETO36878.1 - 0.086 12.3 1.6 0.16 11.4 1.1 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 ETO36878.1 - 0.22 11.4 4.8 1.5 8.7 3.9 2.0 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 ETO36878.1 - 0.25 11.3 9.7 4 7.4 5.5 3.3 2 1 0 2 2 2 0 FANCL C-terminal domain Abhydrolase_9_N PF15420.1 ETO36878.1 - 3.3 7.3 8.5 3.6 7.2 5.1 1.7 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus zf-MIZ PF02891.15 ETO36878.1 - 3.7 7.1 7.0 9.2 5.8 4.9 1.7 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_4 PF14570.1 ETO36878.1 - 3.8 7.1 9.5 0.64 9.6 3.6 2.0 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain CobT PF06213.7 ETO36879.1 - 0.039 13.0 4.5 0.041 13.0 3.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Na_trans_assoc PF06512.8 ETO36879.1 - 0.41 10.5 8.2 0.55 10.1 5.6 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated RNA_polI_A34 PF08208.6 ETO36879.1 - 4.3 6.9 12.5 0.73 9.4 2.7 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Tom37_C PF11801.3 ETO36879.1 - 6.2 6.6 8.9 1.7 8.5 3.0 2.0 2 0 0 2 2 2 0 Tom37 C-terminal domain U-box PF04564.10 ETO36881.1 - 7.9e-11 41.7 0.0 3.4e-10 39.7 0.0 2.1 1 1 0 1 1 1 1 U-box domain DUF3151 PF11349.3 ETO36881.1 - 0.091 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3151) DUF155 PF02582.9 ETO36882.1 - 0.001 18.9 0.1 0.0019 18.1 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Mob1_phocein PF03637.12 ETO36882.1 - 0.2 11.3 4.6 0.088 12.4 1.2 1.8 2 0 0 2 2 2 0 Mob1/phocein family Epimerase PF01370.16 ETO36883.1 - 6.1e-10 38.9 0.0 7.2e-10 38.7 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETO36883.1 - 5.2e-09 35.2 0.0 5.5e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 ETO36883.1 - 8.2e-07 28.2 0.0 1.3e-06 27.5 0.0 1.3 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 ETO36883.1 - 0.0025 17.7 0.0 0.0033 17.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 ETO36883.1 - 0.0029 16.6 0.0 0.0029 16.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 ETO36883.1 - 0.0063 15.4 0.0 0.008 15.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Ldh_1_N PF00056.18 ETO36883.1 - 0.0085 15.9 0.1 0.018 14.9 0.1 1.6 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain KR PF08659.5 ETO36883.1 - 0.011 15.4 0.0 0.02 14.5 0.0 1.3 1 1 0 1 1 1 0 KR domain NmrA PF05368.8 ETO36883.1 - 0.028 13.6 0.0 0.037 13.2 0.0 1.1 1 0 0 1 1 1 0 NmrA-like family Semialdhyde_dh PF01118.19 ETO36883.1 - 0.054 13.7 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 ETO36883.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 1 1 0 1 1 1 0 NADH(P)-binding CCSMST1 PF15013.1 ETO36884.1 - 0.02 14.7 1.8 1.8 8.5 0.1 2.9 2 0 0 2 2 2 0 CCSMST1 family PPPI_inhib PF14895.1 ETO36884.1 - 0.049 12.3 4.5 0.027 13.2 1.6 1.5 1 1 0 1 1 1 0 Protein phosphatase 1 inhibitor Pox_A14 PF05767.7 ETO36884.1 - 0.098 12.6 3.4 0.73 9.8 0.2 3.0 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 EF-hand_1 PF00036.27 ETO36886.1 - 2.5e-07 29.5 0.3 1.9e-06 26.7 0.3 2.5 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 ETO36886.1 - 1.6e-06 28.1 6.7 0.00059 19.9 0.8 3.4 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 ETO36886.1 - 2.4e-05 23.8 0.3 0.00013 21.5 0.2 2.3 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 ETO36886.1 - 0.00011 21.3 0.2 0.00034 19.7 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 ETO36886.1 - 0.013 15.1 1.3 0.049 13.2 0.4 2.3 1 1 1 2 2 2 0 EF-hand domain pair DUF4407 PF14362.1 ETO36886.1 - 0.29 10.0 4.8 0.46 9.3 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3450 PF11932.3 ETO36886.1 - 0.91 8.7 18.9 0.036 13.3 6.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Atg14 PF10186.4 ETO36886.1 - 9.8 5.0 14.6 1.3 7.9 7.1 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 WD40 PF00400.27 ETO36887.1 - 7.8e-07 28.7 0.9 3.7e-06 26.6 0.1 2.3 2 1 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 ETO36887.1 - 0.14 10.2 0.0 0.15 10.1 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Peptidase_S51 PF03575.12 ETO36889.1 - 0.064 12.9 0.0 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 Peptidase family S51 WD40 PF00400.27 ETO36890.1 - 6.9e-173 555.1 58.9 1.1e-11 44.1 0.1 16.3 16 0 0 16 16 16 16 WD domain, G-beta repeat Nup160 PF11715.3 ETO36890.1 - 2.1e-15 55.8 32.7 0.056 11.5 0.3 14.0 1 1 13 15 15 15 9 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETO36890.1 - 3.7e-06 25.4 11.4 0.58 8.3 0.0 6.3 4 2 2 6 6 6 4 Cytochrome D1 heme domain Pentapeptide PF00805.17 ETO36890.1 - 1.1e-05 24.4 0.2 2.3e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 ETO36890.1 - 2.1e-05 24.2 0.1 5.5e-05 22.8 0.1 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) F420_ligase PF01996.11 ETO36890.1 - 2.3e-05 23.6 0.0 2.7 6.9 0.0 4.5 4 0 0 4 4 4 2 F420-0:Gamma-glutamyl ligase Pentapeptide_3 PF13576.1 ETO36890.1 - 0.00074 19.3 0.2 0.0024 17.7 0.2 1.9 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) PD40 PF07676.7 ETO36890.1 - 0.002 17.7 15.7 1.8 8.2 0.0 6.3 7 0 0 7 7 7 3 WD40-like Beta Propeller Repeat Resistin PF06954.6 ETO36890.1 - 0.041 14.1 2.5 66 3.8 0.0 6.0 6 1 1 7 7 7 0 Resistin DUF2141 PF09912.4 ETO36891.1 - 0.11 12.2 0.0 0.34 10.5 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2141) PAH PF02671.16 ETO36893.1 - 2e-06 27.2 0.1 2.9e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Paired amphipathic helix repeat DUF2615 PF11027.3 ETO36893.1 - 0.0088 15.9 1.1 0.015 15.1 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) Mito_fiss_reg PF05308.6 ETO36893.1 - 0.01 15.2 0.8 0.011 15.0 0.6 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 ETO36893.1 - 0.041 13.1 0.9 0.052 12.8 0.6 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Menin PF05053.8 ETO36893.1 - 7.7 4.5 5.7 11 4.0 3.9 1.2 1 0 0 1 1 1 0 Menin Polyhedrin PF00738.13 ETO36894.1 - 0.0081 15.2 0.3 0.0084 15.2 0.2 1.1 1 0 0 1 1 1 1 Polyhedrin DUF496 PF04363.7 ETO36894.1 - 0.016 14.9 3.6 0.05 13.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF496) DUF87 PF01935.12 ETO36895.1 - 0.012 15.4 3.1 0.015 15.1 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF87 Utp12 PF04003.7 ETO36895.1 - 0.087 12.7 0.8 0.15 12.0 0.5 1.4 1 0 0 1 1 1 0 Dip2/Utp12 Family AAA PF00004.24 ETO36895.1 - 0.096 12.8 0.5 0.15 12.2 0.3 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IFT46_B_C PF12317.3 ETO36895.1 - 0.098 12.0 4.7 0.14 11.4 3.3 1.2 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal Cas_Cas4 PF01930.12 ETO36895.1 - 0.4 10.5 4.3 0.55 10.1 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF83 Bap31 PF05529.7 ETO36895.1 - 1.5 8.2 9.3 0.86 9.0 5.1 1.6 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like Bud13 PF09736.4 ETO36895.1 - 1.5 9.0 10.2 2.2 8.5 7.1 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex CENP-B_N PF04218.8 ETO36895.1 - 2.2 7.7 9.7 0.6 9.5 3.0 2.5 2 1 1 3 3 3 0 CENP-B N-terminal DNA-binding domain DUF3347 PF11827.3 ETO36895.1 - 4.2 7.3 12.1 8.3 6.3 8.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3347) ARD PF03079.9 ETO36895.1 - 8 6.3 9.3 13 5.6 6.4 1.3 1 0 0 1 1 1 0 ARD/ARD' family GP40 PF11025.3 ETO36896.1 - 1.2 8.6 5.4 1.6 8.3 3.8 1.3 1 1 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium Pribosyltran PF00156.22 ETO36897.1 - 0.092 12.4 0.4 0.15 11.7 0.3 1.5 1 0 0 1 1 1 0 Phosphoribosyl transferase domain DUF4200 PF13863.1 ETO36897.1 - 1.7 8.6 17.2 0.62 10.0 6.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) APG6 PF04111.7 ETO36898.1 - 0.00074 18.6 12.2 0.00074 18.6 8.5 1.4 1 1 0 1 1 1 1 Autophagy protein Apg6 DUF3086 PF11285.3 ETO36898.1 - 0.019 13.8 1.8 0.021 13.6 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) DUF342 PF03961.8 ETO36898.1 - 0.098 11.0 12.3 0.088 11.2 8.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF778 PF05608.7 ETO36898.1 - 0.099 12.5 0.8 0.13 12.1 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF778) V_ATPase_I PF01496.14 ETO36898.1 - 0.4 8.4 7.2 0.4 8.4 5.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.11 ETO36898.1 - 0.45 9.0 3.7 0.49 8.9 2.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF948 PF06103.6 ETO36898.1 - 0.78 9.6 6.7 1.9 8.4 1.5 2.6 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1795 PF08786.6 ETO36898.1 - 1.5 8.6 4.7 1 9.1 0.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1795) Spc7 PF08317.6 ETO36898.1 - 2.3 6.8 16.8 0.28 9.7 7.9 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Pneumovirus_M2 PF06436.6 ETO36898.1 - 3.4 6.8 8.5 0.56 9.4 0.4 2.3 2 1 1 3 3 3 0 Pneumovirus matrix protein 2 (M2) IncA PF04156.9 ETO36898.1 - 9.8 5.7 16.7 18 4.8 11.6 1.5 1 1 0 1 1 1 0 IncA protein VPS9 PF02204.13 ETO36899.1 - 2.9e-12 46.5 1.4 1.9e-07 31.0 0.0 2.3 2 0 0 2 2 2 2 Vacuolar sorting protein 9 (VPS9) domain CDC45 PF02724.9 ETO36899.1 - 0.0016 16.5 15.0 0.0022 16.1 10.4 1.1 1 0 0 1 1 1 1 CDC45-like protein Orbi_VP6 PF01516.11 ETO36899.1 - 0.079 12.0 8.1 0.13 11.3 5.6 1.3 1 0 0 1 1 1 0 Orbivirus helicase VP6 BUD22 PF09073.5 ETO36899.1 - 0.29 10.1 16.9 0.42 9.6 11.7 1.2 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 ETO36899.1 - 0.3 9.5 18.1 0.49 8.8 12.6 1.3 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 ETO36899.1 - 0.5 8.2 24.2 0.72 7.7 16.8 1.1 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.6 ETO36899.1 - 1.1 7.2 10.8 1.5 6.8 7.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CobT PF06213.7 ETO36899.1 - 6.1 5.8 20.0 10 5.1 13.9 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4458 PF14660.1 ETO36900.1 - 0.049 13.6 0.3 0.08 12.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4458) WD40 PF00400.27 ETO36901.1 - 2.4e-38 128.6 13.4 9e-11 41.2 0.1 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO36901.1 - 2.3e-05 22.7 2.1 0.0019 16.4 0.1 2.7 1 1 0 2 2 2 2 Nucleoporin Nup120/160 Kelch_6 PF13964.1 ETO36902.1 - 0.21 11.8 5.8 6.5 7.1 0.3 3.4 3 0 0 3 3 3 0 Kelch motif CD4-extracel PF09191.5 ETO36902.1 - 0.34 10.9 0.1 0.34 10.9 0.1 1.8 2 0 0 2 2 2 0 CD4, extracellular LRR_6 PF13516.1 ETO36905.1 - 9.1e-08 31.4 11.2 0.19 11.9 0.0 6.5 6 0 0 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.2 ETO36905.1 - 9.1e-06 25.1 2.5 0.23 11.1 0.1 3.8 3 2 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETO36905.1 - 0.00024 20.7 5.2 33 5.0 0.0 6.2 6 0 0 6 6 6 1 Leucine Rich Repeat Pex26 PF07163.7 ETO36905.1 - 0.4 9.5 6.9 0.8 8.5 4.8 1.4 1 0 0 1 1 1 0 Pex26 protein Receptor_2B4 PF11465.3 ETO36906.1 - 0.025 14.5 0.6 0.11 12.3 0.0 2.4 2 1 0 2 2 2 0 Natural killer cell receptor 2B4 LRR_6 PF13516.1 ETO36907.1 - 2.5e-14 51.6 11.2 0.015 15.2 0.0 7.9 7 1 1 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.2 ETO36907.1 - 1.1e-11 44.0 1.9 0.031 13.8 0.1 4.7 4 1 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETO36907.1 - 4.4e-05 22.9 4.1 46 4.6 0.0 6.4 5 1 1 6 6 6 0 Leucine Rich Repeat LRR_7 PF13504.1 ETO36907.1 - 0.0031 17.4 2.1 25 5.6 0.0 5.4 6 0 0 6 6 6 0 Leucine rich repeat LRR_8 PF13855.1 ETO36907.1 - 0.0032 17.1 7.7 18 5.2 0.0 5.4 3 1 3 6 6 6 3 Leucine rich repeat RhoGAP PF00620.22 ETO36907.1 - 0.09 12.3 0.2 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 RhoGAP domain Kelch_1 PF01344.20 ETO36908.1 - 9.1e-08 31.5 4.1 0.00055 19.4 0.1 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 ETO36908.1 - 8e-07 28.8 0.7 0.059 13.3 0.1 4.7 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 ETO36908.1 - 1.7e-06 27.6 0.0 0.053 13.2 0.0 3.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO36908.1 - 2.5e-05 24.2 4.8 0.19 11.9 0.1 4.7 4 1 1 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETO36908.1 - 0.00043 19.9 6.1 0.81 9.5 0.6 5.0 5 1 0 5 5 5 2 Kelch motif YaaC PF14175.1 ETO36909.1 - 0.057 12.3 3.3 0.059 12.3 2.3 1.0 1 0 0 1 1 1 0 YaaC-like Protein Methyltransf_FA PF12248.3 ETO36910.1 - 4e-18 65.3 0.3 6.8e-18 64.5 0.2 1.3 1 0 0 1 1 1 1 Farnesoic acid 0-methyl transferase DUF1768 PF08719.6 ETO36910.1 - 0.055 13.1 1.8 3.6 7.2 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1768) DnaJ PF00226.26 ETO36911.1 - 2.2e-24 84.9 3.2 1.9e-20 72.3 0.6 2.7 2 0 0 2 2 2 2 DnaJ domain SAPS PF04499.10 ETO36911.1 - 0.21 10.2 13.2 0.0091 14.6 4.2 1.9 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.11 ETO36911.1 - 0.69 9.7 11.4 0.52 10.1 4.8 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region HSP70 PF00012.15 ETO36912.1 - 8.5e-05 20.6 0.0 0.00011 20.2 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein Peptidase_M22 PF00814.20 ETO36912.1 - 0.02 14.3 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Glycoprotease family YhfZ_C PF14503.1 ETO36912.1 - 0.12 11.7 0.1 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 YhfZ C-terminal domain HSP70 PF00012.15 ETO36913.1 - 0.00017 19.6 0.0 0.00022 19.3 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein LNS2 PF08235.8 ETO36914.1 - 1.3e-55 187.3 0.0 2.8e-55 186.2 0.0 1.6 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 ETO36914.1 - 1.2e-22 79.7 2.7 2.2e-16 59.5 0.0 3.2 3 0 0 3 3 3 2 lipin, N-terminal conserved region DUF4475 PF14753.1 ETO36915.1 - 0.0009 18.8 1.0 0.0075 15.8 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4475) CUE PF02845.11 ETO36916.1 - 0.0042 16.5 0.0 0.0075 15.7 0.0 1.4 1 0 0 1 1 1 1 CUE domain PUB PF09409.5 ETO36916.1 - 0.018 14.7 0.3 0.2 11.4 0.2 2.5 1 1 0 1 1 1 0 PUB domain SET PF00856.23 ETO36917.1 - 0.0026 18.0 0.0 0.0026 18.0 0.0 3.0 3 1 0 3 3 3 1 SET domain zf-C2H2 PF00096.21 ETO36917.1 - 0.015 15.5 0.5 0.015 15.5 0.3 6.2 7 0 0 7 7 7 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETO36917.1 - 4.5 7.8 28.2 0.14 12.5 0.3 5.1 4 0 0 4 4 4 0 C2H2-type zinc finger SET PF00856.23 ETO36918.1 - 1.4e-17 64.4 0.3 4e-17 62.9 0.2 1.8 1 1 0 1 1 1 1 SET domain Exo_endo_phos_2 PF14529.1 ETO36919.1 - 6e-10 38.7 2.5 1.1e-07 31.4 1.8 2.6 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase DUF2346 PF09803.4 ETO36919.1 - 0.0033 17.2 4.8 0.022 14.5 0.3 2.8 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2346) RRM_6 PF14259.1 ETO36921.1 - 0.0034 17.3 0.0 0.013 15.4 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETO36921.1 - 0.0064 16.0 0.3 0.083 12.5 0.1 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribonuc_red_lgC PF02867.10 ETO36922.1 - 1.8e-47 162.1 0.0 2.2e-47 161.8 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain DUF2812 PF11193.3 ETO36922.1 - 0.1 12.7 0.9 0.47 10.6 0.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2812) Ribonuc_red_lgC PF02867.10 ETO36923.1 - 1.7e-138 462.5 1.1 1.1e-117 393.9 0.0 2.2 2 0 0 2 2 2 2 Ribonucleotide reductase, barrel domain NRDD PF13597.1 ETO36923.1 - 5.9e-05 21.3 0.0 8.2e-05 20.8 0.0 1.1 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase WD40 PF00400.27 ETO36924.1 - 3.8e-53 175.5 26.0 1.6e-10 40.4 0.8 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO36924.1 - 1.1e-07 30.4 3.2 0.0011 17.1 0.9 3.6 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Actin PF00022.14 ETO36925.1 - 1.8e-74 250.5 0.0 2.6e-74 250.0 0.0 1.1 1 0 0 1 1 1 1 Actin Pkinase PF00069.20 ETO36926.1 - 1.4e-13 50.6 0.1 5e-11 42.2 0.1 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO36926.1 - 5.6e-05 22.3 0.1 0.092 11.7 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pox_RNA_Pol_19 PF05320.7 ETO36926.1 - 0.088 12.5 1.3 0.097 12.4 0.9 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF2115 PF09888.4 ETO36927.1 - 0.0069 16.5 2.8 0.02 15.0 0.4 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2115) Pkinase PF00069.20 ETO36928.1 - 0.002 17.2 0.0 0.002 17.2 0.0 2.8 3 0 0 3 3 3 1 Protein kinase domain Pkinase PF00069.20 ETO36929.1 - 6.6e-20 71.3 0.2 2e-14 53.3 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETO36929.1 - 0.00013 21.1 0.1 0.00038 19.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Seryl_tRNA_N PF02403.17 ETO36929.1 - 0.017 15.1 2.3 0.031 14.2 1.6 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain SRP-alpha_N PF04086.8 ETO36929.1 - 0.027 13.8 0.6 0.042 13.2 0.4 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Fzo_mitofusin PF04799.8 ETO36929.1 - 0.031 13.6 0.8 0.082 12.2 0.6 1.7 1 0 0 1 1 1 0 fzo-like conserved region DUF1090 PF06476.7 ETO36929.1 - 0.033 13.8 1.4 0.06 13.0 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) DUF1359 PF07097.6 ETO36929.1 - 0.074 13.1 0.3 0.18 11.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1359) CCDC-167 PF15188.1 ETO36929.1 - 0.41 10.6 5.3 0.53 10.2 1.3 2.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DUF2846 PF11008.3 ETO36931.1 - 0.043 13.6 0.2 0.4 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2846) DUF3278 PF11683.3 ETO36931.1 - 0.059 13.3 0.1 0.13 12.3 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3278) CorA PF01544.13 ETO36932.1 - 0.064 12.2 0.6 0.096 11.6 0.4 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Fmp27_WPPW PF10359.4 ETO36932.1 - 0.31 9.4 11.3 0.43 8.9 7.8 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain zf-CCHC_4 PF14392.1 ETO36932.1 - 0.63 9.7 10.8 0.28 10.8 0.7 2.6 1 1 1 2 2 2 0 Zinc knuckle DUF2992 PF11208.3 ETO36932.1 - 4 7.3 13.9 7.9 6.3 7.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2992) Ndc1_Nup PF09531.5 ETO36932.1 - 7 4.9 9.1 9.1 4.5 6.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup WD40 PF00400.27 ETO36933.1 - 4.4e-16 58.0 2.0 6.5e-09 35.3 0.1 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 ETO36933.1 - 6e-07 27.9 0.0 0.0062 14.7 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Secretin_N_2 PF07655.8 ETO36933.1 - 9.9 6.6 7.2 4.6 7.6 2.3 2.6 2 1 0 2 2 2 0 Secretin N-terminal domain Kelch_2 PF07646.10 ETO36934.1 - 9.9e-09 34.6 0.6 0.0056 16.3 0.1 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 ETO36934.1 - 3.4e-08 33.2 0.9 0.4 10.6 0.1 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 ETO36934.1 - 6.1e-07 28.8 2.2 0.0015 17.9 0.2 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO36934.1 - 1.1e-06 28.5 1.6 0.0062 16.6 0.2 4.2 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 ETO36934.1 - 2.4e-05 24.0 0.8 0.98 9.2 0.1 3.9 3 0 0 3 3 3 2 Galactose oxidase, central domain DUF2414 PF10309.4 ETO36934.1 - 0.068 12.8 0.3 0.17 11.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2414) Kelch_4 PF13418.1 ETO36935.1 - 5e-08 32.6 2.4 7.2e-05 22.4 0.2 3.8 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETO36935.1 - 9.8e-08 31.8 1.5 3 8.1 0.2 4.9 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.20 ETO36935.1 - 7e-06 25.4 5.2 0.0028 17.1 0.5 4.5 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.10 ETO36935.1 - 1.3e-05 24.6 1.7 0.018 14.7 0.2 4.4 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 ETO36935.1 - 0.0013 18.6 0.3 11 6.0 0.2 4.7 5 0 0 5 5 5 1 Kelch motif Copper-bind PF00127.15 ETO36935.1 - 0.016 15.4 0.2 0.054 13.7 0.2 2.0 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Peptidase_S10 PF00450.17 ETO36936.1 - 2.8e-27 95.9 0.2 3.4e-27 95.6 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Kelch_1 PF01344.20 ETO36937.1 - 1e-08 34.5 5.7 2.8e-05 23.5 0.4 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 ETO36937.1 - 6.8e-07 29.2 4.1 0.15 12.3 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 ETO36937.1 - 2e-06 27.4 2.7 0.00028 20.6 0.0 3.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 ETO36937.1 - 5.2e-06 26.0 1.7 0.0055 16.4 0.1 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 ETO36937.1 - 1.2e-05 25.1 1.5 0.12 12.4 0.3 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 ETO36937.1 - 0.017 15.2 1.4 0.086 13.0 0.0 2.9 3 0 0 3 3 3 0 Galactose oxidase, central domain rve PF00665.21 ETO36938.1 - 1.2e-07 31.8 0.0 4.6e-07 29.9 0.0 1.9 1 1 0 1 1 1 1 Integrase core domain RNA_pol_L_2 PF13656.1 ETO36938.1 - 0.13 11.7 0.1 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain RVT_1 PF00078.22 ETO36939.1 - 1e-17 64.2 0.2 2.7e-17 62.8 0.0 1.8 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DSPc PF00782.15 ETO36940.1 - 5.4e-20 71.3 0.5 7.7e-20 70.8 0.4 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 ETO36940.1 - 0.0082 15.4 0.2 0.022 14.0 0.0 1.7 1 1 1 2 2 2 1 Protein-tyrosine phosphatase Kelch_6 PF13964.1 ETO36941.1 - 1.2e-08 34.7 0.7 0.051 13.7 0.1 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 ETO36941.1 - 6e-08 32.0 3.9 0.0019 17.7 0.3 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 ETO36941.1 - 3.4e-06 26.6 2.2 2.7 7.9 0.1 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.1 ETO36941.1 - 6.4e-06 25.8 0.1 0.023 14.4 0.0 3.0 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETO36941.1 - 0.016 15.1 1.6 27 4.8 0.0 4.1 4 0 0 4 4 4 0 Kelch motif TPR_11 PF13414.1 ETO36942.1 - 5.4e-11 41.9 8.3 0.0024 17.4 0.0 6.2 4 3 3 7 7 7 4 TPR repeat TPR_17 PF13431.1 ETO36942.1 - 9.3e-10 37.9 1.2 0.016 15.3 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETO36942.1 - 1.1e-08 35.5 0.1 0.16 12.6 0.0 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETO36942.1 - 2.9e-07 29.8 0.3 1.4 8.6 0.0 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETO36942.1 - 4.2e-07 29.4 4.7 0.86 9.6 0.1 7.2 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETO36942.1 - 2.6e-06 26.7 5.4 0.31 10.9 0.0 6.9 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETO36942.1 - 0.00074 19.8 8.5 0.0037 17.5 0.2 4.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETO36942.1 - 0.0021 17.9 5.1 1.7 8.6 0.0 5.1 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETO36942.1 - 0.013 15.2 0.5 6.9 6.7 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Cofilin_ADF PF00241.15 ETO36944.1 - 7.5e-23 80.7 0.5 1e-22 80.3 0.4 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein TRP PF06011.7 ETO36945.1 - 0.0052 15.4 3.0 0.0052 15.4 2.1 1.9 1 1 0 2 2 2 1 Transient receptor potential (TRP) ion channel Tetraspannin PF00335.15 ETO36945.1 - 0.024 13.9 5.9 0.0086 15.3 2.2 1.9 1 1 0 1 1 1 0 Tetraspanin family DUF912 PF06024.7 ETO36945.1 - 0.029 14.4 1.0 0.029 14.4 0.7 2.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) MRAP PF15183.1 ETO36945.1 - 0.033 13.7 1.7 0.033 13.7 1.2 2.5 3 0 0 3 3 3 0 Melanocortin-2 receptor accessory protein family YwiC PF14256.1 ETO36945.1 - 0.037 14.1 6.5 0.11 12.5 0.2 3.0 3 0 0 3 3 3 0 YwiC-like protein CAML PF14963.1 ETO36945.1 - 0.13 11.6 0.2 0.22 10.8 0.2 1.4 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand OAD_gamma PF04277.8 ETO36945.1 - 0.13 12.6 1.8 18 5.7 0.0 2.6 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Rhabdo_glycop PF00974.13 ETO36945.1 - 0.26 9.5 0.1 0.26 9.5 0.0 2.2 2 1 0 3 3 3 0 Rhabdovirus spike glycoprotein PSI_PsaF PF02507.10 ETO36945.1 - 0.35 10.4 2.5 0.35 10.4 0.5 1.9 2 0 0 2 2 2 0 Photosystem I reaction centre subunit III DUF3816 PF12822.2 ETO36945.1 - 0.98 9.2 13.1 0.059 13.2 3.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3816) Chordopox_L2 PF05803.7 ETO36945.1 - 1.8 8.2 9.1 0.83 9.3 0.1 3.2 3 1 0 3 3 3 0 Chordopoxvirus L2 protein HemY_N PF07219.8 ETO36945.1 - 2.1 7.9 6.7 7.6 6.1 0.2 3.1 3 0 0 3 3 3 0 HemY protein N-terminus DUF3270 PF11674.3 ETO36945.1 - 6.7 6.8 13.8 0.041 13.8 1.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3270) EPL1 PF10513.4 ETO36946.1 - 0.45 10.7 7.4 1.1 9.4 5.1 1.6 1 0 0 1 1 1 0 Enhancer of polycomb-like P22_Tail-4 PF11650.3 ETO36947.1 - 0.026 14.0 0.1 0.048 13.2 0.1 1.4 1 0 0 1 1 1 0 P22 tail accessory factor KH_1 PF00013.24 ETO36948.1 - 3.7e-08 32.8 0.7 8.1e-07 28.5 0.0 2.2 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 ETO36948.1 - 0.17 11.5 0.6 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 KH domain WD40 PF00400.27 ETO36950.1 - 3.3e-25 86.9 9.7 1.5e-10 40.5 1.4 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat DDE_3 PF13358.1 ETO36950.1 - 3.2e-05 23.7 0.3 5e-05 23.0 0.2 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease Nup160 PF11715.3 ETO36950.1 - 0.00072 17.8 0.1 0.0011 17.1 0.1 1.5 1 1 0 1 1 1 1 Nucleoporin Nup120/160 rve_2 PF13333.1 ETO36950.1 - 0.083 12.9 1.3 2.1 8.4 0.1 2.6 2 0 0 2 2 2 0 Integrase core domain Kelch_2 PF07646.10 ETO36950.1 - 0.085 12.6 1.0 4.2 7.3 0.1 2.9 2 1 0 2 2 2 0 Kelch motif His_Phos_1 PF00300.17 ETO36952.1 - 8.8e-09 35.6 0.0 1.2e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ADH_N PF08240.7 ETO36953.1 - 3.1e-07 30.1 0.0 1.6e-06 27.8 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Metallophos PF00149.23 ETO36954.1 - 2.2e-40 138.2 0.1 2.9e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CENP-F_leu_zip PF10473.4 ETO36955.1 - 0.0024 17.7 8.7 0.0037 17.1 6.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TBPIP PF07106.8 ETO36955.1 - 0.0026 17.3 6.6 0.0035 16.9 4.6 1.2 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) MAD PF05557.8 ETO36955.1 - 0.0029 15.7 3.7 0.0035 15.5 2.6 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein CCDC155 PF14662.1 ETO36955.1 - 0.0031 17.1 3.4 0.0038 16.8 2.3 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 Mito_fiss_reg PF05308.6 ETO36955.1 - 0.0062 15.9 0.8 0.0094 15.3 0.6 1.2 1 0 0 1 1 1 1 Mitochondrial fission regulator BLOC1_2 PF10046.4 ETO36955.1 - 0.0086 16.2 7.6 0.045 13.8 2.1 2.2 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF904 PF06005.7 ETO36955.1 - 0.0087 16.3 12.2 0.048 13.9 3.8 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF904) APG6 PF04111.7 ETO36955.1 - 0.012 14.6 5.4 0.014 14.4 3.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 ETO36955.1 - 0.014 13.8 2.8 0.014 13.8 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DivIC PF04977.10 ETO36955.1 - 0.025 14.0 6.5 0.28 10.6 1.8 2.5 2 0 0 2 2 2 0 Septum formation initiator Pox_A22 PF04848.8 ETO36955.1 - 0.03 14.2 5.1 0.074 12.9 1.8 2.0 1 1 1 2 2 2 0 Poxvirus A22 protein Phage_lysis PF03245.8 ETO36955.1 - 0.13 12.2 3.4 0.12 12.3 1.6 1.5 1 1 0 1 1 1 0 Bacteriophage Rz lysis protein FlaC_arch PF05377.6 ETO36955.1 - 0.13 12.1 0.3 0.13 12.1 0.2 2.6 2 1 1 3 3 2 0 Flagella accessory protein C (FlaC) Pox_A_type_inc PF04508.7 ETO36955.1 - 0.16 11.8 4.2 0.69 9.8 0.1 3.2 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat bZIP_1 PF00170.16 ETO36955.1 - 0.21 11.5 8.6 0.23 11.4 2.6 2.4 2 0 0 2 2 2 0 bZIP transcription factor DASH_Dad3 PF08656.5 ETO36955.1 - 0.22 11.2 6.1 0.73 9.5 1.1 2.4 1 1 1 2 2 2 0 DASH complex subunit Dad3 Shugoshin_N PF07558.6 ETO36955.1 - 0.22 11.2 6.5 2.2 8.0 0.2 3.4 3 1 0 3 3 3 0 Shugoshin N-terminal coiled-coil region DUF724 PF05266.9 ETO36955.1 - 0.27 10.8 5.6 0.38 10.3 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Striatin PF08232.7 ETO36955.1 - 0.35 11.1 5.7 0.14 12.5 1.9 1.8 1 1 1 2 2 2 0 Striatin family Prefoldin PF02996.12 ETO36955.1 - 0.37 10.4 6.4 1.3 8.6 2.3 2.2 2 0 0 2 2 2 0 Prefoldin subunit DUF2408 PF10303.4 ETO36955.1 - 0.42 10.7 6.0 5.6 7.0 4.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) DUF1843 PF08898.5 ETO36955.1 - 0.47 10.5 2.9 2.3 8.2 0.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1843) TMF_DNA_bd PF12329.3 ETO36955.1 - 0.5 10.1 13.5 0.45 10.3 4.6 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 ETO36955.1 - 0.6 9.6 8.5 1.2 8.7 5.9 1.4 1 1 0 1 1 1 0 IncA protein Exonuc_VII_L PF02601.10 ETO36955.1 - 0.94 8.6 5.4 1.1 8.4 3.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4094 PF13334.1 ETO36955.1 - 1.3 9.4 4.7 6.8 7.1 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) CENP-Q PF13094.1 ETO36955.1 - 1.3 8.9 13.3 30 4.5 9.2 2.1 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4140 PF13600.1 ETO36955.1 - 1.5 9.3 4.8 8.8 6.8 3.4 2.1 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) OmpH PF03938.9 ETO36955.1 - 2 8.3 7.4 2.9 7.8 5.2 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Med4 PF10018.4 ETO36955.1 - 3.7 6.9 6.8 12 5.2 0.4 2.1 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 HALZ PF02183.13 ETO36955.1 - 3.8 7.3 10.0 0.88 9.3 1.5 2.9 3 1 0 3 3 2 0 Homeobox associated leucine zipper DUF972 PF06156.8 ETO36955.1 - 3.9 7.8 8.0 27 5.1 5.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF972) M PF02370.11 ETO36955.1 - 4.3 8.0 9.0 3.6 8.2 1.4 3.3 2 1 0 2 2 2 0 M protein repeat DUF2968 PF11180.3 ETO36955.1 - 5.3 6.3 9.4 0.28 10.5 2.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) bZIP_2 PF07716.10 ETO36955.1 - 7.4 6.4 8.5 5 7.0 0.2 2.7 2 1 0 2 2 2 0 Basic region leucine zipper Abhydrolase_5 PF12695.2 ETO36956.1 - 5.7e-07 29.3 0.0 1.2e-06 28.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETO36956.1 - 0.0092 15.8 0.0 0.032 14.0 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family WD40 PF00400.27 ETO36957.1 - 2.4e-23 81.0 11.5 1.2e-06 28.1 0.3 5.3 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 ETO36957.1 - 0.0041 16.8 0.7 0.81 9.3 0.2 2.9 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 ETO36957.1 - 0.075 11.2 0.0 0.99 7.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Pkinase PF00069.20 ETO36958.1 - 1.7e-36 125.7 0.0 2.2e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETO36958.1 - 5e-13 48.7 0.0 7.2e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PEPcase PF00311.12 ETO36958.1 - 0.00018 19.5 0.3 0.00024 19.1 0.2 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase Kinase-like PF14531.1 ETO36958.1 - 0.00027 20.0 0.0 0.00032 19.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like G-alpha PF00503.15 ETO36959.1 - 2.1e-57 194.5 0.2 2.5e-57 194.3 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETO36959.1 - 1.3e-07 31.0 2.1 0.00017 20.8 0.0 2.8 2 1 1 3 3 3 2 ADP-ribosylation factor family AAA_29 PF13555.1 ETO36959.1 - 0.0065 15.9 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Mg_chelatase PF01078.16 ETO36959.1 - 0.0067 15.6 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.18 ETO36959.1 - 0.0079 16.1 0.0 0.17 11.8 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.22 ETO36959.1 - 0.0086 16.3 0.1 0.017 15.4 0.1 1.4 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.13 ETO36959.1 - 0.013 15.0 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family NB-ARC PF00931.17 ETO36959.1 - 0.014 14.2 0.3 0.021 13.6 0.2 1.2 1 0 0 1 1 1 0 NB-ARC domain Miro PF08477.8 ETO36959.1 - 0.027 14.9 0.5 0.39 11.2 0.2 2.3 2 1 0 2 2 2 0 Miro-like protein AAA_17 PF13207.1 ETO36959.1 - 0.037 14.8 0.0 0.062 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 ETO36959.1 - 0.077 12.8 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain EIIBC-GUT_N PF03612.9 ETO36960.1 - 0.015 14.9 3.1 0.016 14.7 2.1 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Kei1 PF08552.6 ETO36960.1 - 0.18 11.4 0.8 0.19 11.3 0.6 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF1460 PF07313.7 ETO36960.1 - 0.39 9.8 4.4 0.39 9.8 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) DUF3974 PF13120.1 ETO36960.1 - 5.7 6.7 12.7 8.4 6.2 8.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3974) DUF4551 PF15087.1 ETO36961.1 - 0.53 8.5 6.7 0.87 7.8 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Apc15p PF05841.6 ETO36964.1 - 2.1 9.0 6.8 3.2 8.4 4.7 1.2 1 0 0 1 1 1 0 Apc15p protein SNARE PF05739.14 ETO36965.1 - 1.6e-08 34.0 3.3 1.6e-08 34.0 2.3 1.4 2 0 0 2 2 2 1 SNARE domain Tweety PF04906.8 ETO36965.1 - 0.02 13.3 0.5 0.023 13.1 0.4 1.0 1 0 0 1 1 1 0 Tweety Phasin PF05597.6 ETO36965.1 - 0.047 13.4 0.7 0.057 13.1 0.5 1.1 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) B PF02216.11 ETO36965.1 - 0.057 13.1 0.5 0.12 12.2 0.2 1.6 2 0 0 2 2 2 0 B domain Shisa PF13908.1 ETO36965.1 - 2 8.5 4.4 0.95 9.6 0.6 1.8 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DASH_Ask1 PF08655.5 ETO36966.1 - 1.3 8.8 4.4 0.87 9.4 0.1 2.6 2 0 0 2 2 2 0 DASH complex subunit Ask1 Proteasome PF00227.21 ETO36967.1 - 6.7e-14 51.6 3.4 1e-12 47.7 1.6 2.4 2 1 0 2 2 2 1 Proteasome subunit ENTH PF01417.15 ETO36969.1 - 8.6e-35 119.3 0.3 2.1e-34 118.0 0.2 1.6 1 1 0 1 1 1 1 ENTH domain ANTH PF07651.11 ETO36969.1 - 3.4e-05 22.6 0.0 9.1e-05 21.2 0.0 1.6 2 0 0 2 2 2 1 ANTH domain zf-C3HC4_3 PF13920.1 ETO36970.1 - 0.019 14.6 12.1 0.019 14.6 8.4 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) UBX PF00789.15 ETO36971.1 - 3e-10 40.0 0.0 5.9e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 UBX domain Aldedh PF00171.17 ETO36972.1 - 1.2e-57 195.3 0.1 2.1e-56 191.1 0.0 1.9 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Beach PF02138.13 ETO36973.1 - 8.4e-22 77.8 0.1 8.4e-22 77.8 0.1 1.6 2 0 0 2 2 2 1 Beige/BEACH domain WD40 PF00400.27 ETO36973.1 - 1.4e-11 43.7 0.1 2.5e-05 23.9 0.0 5.2 6 0 0 6 6 6 2 WD domain, G-beta repeat Sporozoite_P67 PF05642.6 ETO36973.1 - 0.11 10.3 3.2 0.15 9.8 2.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2457 PF10446.4 ETO36973.1 - 1 8.0 14.9 1.6 7.3 10.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 ETO36973.1 - 1.3 7.0 7.0 1.9 6.4 4.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3245 PF11595.3 ETO36973.1 - 2.4 8.4 10.9 4.5 7.5 7.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) RRN3 PF05327.6 ETO36973.1 - 2.4 6.1 7.7 4.2 5.3 5.3 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PBP1_TM PF14812.1 ETO36973.1 - 9.6 6.5 13.0 21 5.4 9.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WD40 PF00400.27 ETO36974.1 - 5.2e-66 216.3 25.2 3e-12 45.9 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETO36974.1 - 2.1e-11 42.7 5.5 0.00067 17.9 0.1 4.3 2 1 2 4 4 4 4 Nucleoporin Nup120/160 LicD PF04991.8 ETO36976.1 - 4.3e-08 33.5 4.4 1e-07 32.2 2.7 2.1 2 1 0 2 2 2 1 LicD family DUF4381 PF14316.1 ETO36976.1 - 2.5 8.1 6.5 30 4.7 0.6 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) Mitofilin PF09731.4 ETO36977.1 - 1.7 7.2 21.2 1.9 7.0 14.7 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF1777 PF08648.7 ETO36977.1 - 3.4 7.3 26.1 4.4 7.0 18.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) PH PF00169.24 ETO36980.1 - 3.1e-13 49.8 1.5 3.1e-13 49.8 1.0 1.9 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 ETO36980.1 - 3e-08 33.9 4.5 3e-08 33.9 3.1 2.9 3 1 0 3 3 3 1 Pleckstrin homology domain PH_8 PF15409.1 ETO36980.1 - 5.2e-08 32.8 1.2 1.2e-07 31.6 0.9 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 ETO36980.1 - 3.9e-06 26.6 0.9 1e-05 25.3 0.6 1.7 1 0 0 1 1 1 1 PH domain PH_6 PF15406.1 ETO36980.1 - 0.00019 21.4 0.6 0.00049 20.1 0.2 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain DUF3454 PF11936.3 ETO36980.1 - 0.81 9.9 3.3 0.55 10.4 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3454) Asp PF00026.18 ETO36981.1 - 2.3e-05 23.7 0.2 4e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease CCDC32 PF14989.1 ETO36981.1 - 0.084 12.7 0.0 3.3 7.5 0.0 2.5 2 0 0 2 2 2 0 Coiled-coil domain containing 32 ubiquitin PF00240.18 ETO36982.1 - 3.3e-18 64.8 4.6 6.7e-13 47.8 0.2 2.8 3 0 0 3 3 3 2 Ubiquitin family Rad60-SLD PF11976.3 ETO36982.1 - 6.7e-10 38.5 1.5 1.1e-06 28.2 0.1 3.1 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 ETO36982.1 - 0.027 14.6 0.2 0.36 11.1 0.1 2.7 2 1 0 2 2 2 0 Ubiquitin-like domain Dus PF01207.12 ETO36983.1 - 4e-29 101.4 0.0 5e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF1640 PF07798.6 ETO36984.1 - 0.31 11.0 10.0 0.33 10.9 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) SPRY PF00622.23 ETO36985.1 - 0.00075 19.5 0.1 0.0018 18.3 0.0 1.7 1 0 0 1 1 1 1 SPRY domain Mit_KHE1 PF10173.4 ETO36985.1 - 0.37 10.5 4.1 0.72 9.6 2.9 1.5 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF693 PF05113.8 ETO36986.1 - 0.036 12.9 0.1 0.041 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF693) PQ-loop PF04193.9 ETO36987.1 - 1.8e-17 62.6 10.4 2.1e-11 43.1 2.4 2.9 4 0 0 4 4 4 2 PQ loop repeat Kei1 PF08552.6 ETO36987.1 - 0.034 13.8 4.7 0.099 12.2 3.3 1.7 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 zf-C2H2 PF00096.21 ETO36988.1 - 0.0012 19.0 3.6 0.008 16.4 0.2 3.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETO36988.1 - 0.0064 16.7 2.9 0.048 13.9 0.2 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-BED PF02892.10 ETO36988.1 - 0.016 14.9 10.0 0.089 12.5 2.1 3.1 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.1 ETO36988.1 - 0.026 14.4 0.2 0.026 14.4 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 ETO36988.1 - 0.054 13.7 1.0 0.28 11.4 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 ETO36988.1 - 0.2 12.0 7.3 2.7 8.4 1.5 3.1 2 0 0 2 2 2 0 Zinc-finger double domain Pox_E10 PF04805.7 ETO36988.1 - 0.26 10.8 6.8 0.45 10.0 0.6 3.2 3 0 0 3 3 3 0 E10-like protein conserved region ABC1 PF03109.11 ETO36989.1 - 7.3e-18 64.6 0.4 4.7e-10 39.4 0.0 2.4 2 0 0 2 2 2 2 ABC1 family APH PF01636.18 ETO36990.1 - 0.01 15.5 0.1 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Herpes_ICP4_N PF03584.10 ETO36990.1 - 0.087 12.3 0.0 0.44 10.0 0.0 1.9 2 0 0 2 2 2 0 Herpesvirus ICP4-like protein N-terminal region Cation_efflux PF01545.16 ETO36992.1 - 1.2e-23 83.6 10.3 1.4e-23 83.3 7.1 1.1 1 0 0 1 1 1 1 Cation efflux family NAD_binding_8 PF13450.1 ETO36993.1 - 2.7e-06 27.3 0.1 6e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 ETO36993.1 - 4.8e-06 25.9 0.0 2.6e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 ETO36993.1 - 4.1e-05 22.6 0.3 5.4e-05 22.2 0.2 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 ETO36993.1 - 9.9e-05 22.2 0.1 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETO36993.1 - 0.00013 21.0 0.0 0.00016 20.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 ETO36993.1 - 0.0032 16.5 0.2 0.0053 15.8 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 ETO36993.1 - 0.0038 16.1 0.1 0.0083 15.0 0.0 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 ETO36993.1 - 0.0045 16.1 0.0 0.0085 15.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 ETO36993.1 - 0.0053 17.1 0.1 0.012 15.9 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETO36993.1 - 0.018 15.0 0.1 0.025 14.6 0.1 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 ETO36993.1 - 0.16 11.0 0.5 0.25 10.3 0.1 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase Amino_oxidase PF01593.19 ETO36994.1 - 6.3e-10 38.7 0.0 6.8e-10 38.6 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Amino_oxidase PF01593.19 ETO36995.1 - 9.6e-06 24.9 0.2 1.4e-05 24.4 0.2 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase PBP1_TM PF14812.1 ETO36995.1 - 0.14 12.4 0.1 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2439 PF10382.4 ETO36996.1 - 0.0066 16.6 0.9 0.046 13.9 0.7 2.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) PUB PF09409.5 ETO36997.1 - 0.012 15.3 1.3 0.069 12.9 0.4 2.5 2 1 0 2 2 2 0 PUB domain HalX PF08663.5 ETO36997.1 - 0.017 15.0 0.2 7.6 6.5 0.0 2.4 2 0 0 2 2 2 0 HalX domain GCOM2 PF15328.1 ETO36997.1 - 0.098 12.3 1.4 0.87 9.2 0.1 2.0 2 0 0 2 2 2 0 Putative GRINL1B complex locus protein 2 EMP24_GP25L PF01105.19 ETO36997.1 - 0.12 12.1 1.2 1.1 8.9 0.1 2.2 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD ACDC PF14733.1 ETO36997.1 - 0.85 9.7 0.0 0.85 9.7 0.0 2.7 2 1 0 2 2 2 0 AP2-coincident C-terminal ATG_C PF09333.6 ETO36998.1 - 2.9e-19 69.0 0.0 7.8e-19 67.6 0.0 1.7 1 0 0 1 1 1 1 ATG C terminal domain Radial_spoke PF04712.7 ETO36999.1 - 0.64 8.6 13.5 0.42 9.2 8.4 1.3 1 1 0 1 1 1 0 Radial spokehead-like protein DUF3776 PF12618.3 ETO36999.1 - 0.67 10.5 11.3 0.26 11.8 4.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3776) Drf_GBD PF06371.8 ETO36999.1 - 2.5 7.4 7.5 0.88 8.9 0.2 2.2 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain Cwf_Cwc_15 PF04889.7 ETO36999.1 - 3.6 7.2 13.5 1.7 8.2 5.6 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Bravo_FIGEY PF13882.1 ETO36999.1 - 4.1 8.3 7.5 1.5 9.7 2.7 2.2 1 1 1 2 2 2 0 Bravo-like intracellular region zf-TRAF PF02176.13 ETO37001.1 - 3.4e-06 27.3 1.3 3.4e-06 27.3 0.9 2.9 3 1 0 3 3 3 1 TRAF-type zinc finger zf-RING_2 PF13639.1 ETO37001.1 - 0.0089 15.8 1.6 0.0089 15.8 1.1 2.7 5 0 0 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETO37001.1 - 3.1 7.8 10.0 0.26 11.3 0.9 3.3 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L7Ae PF01248.21 ETO37002.1 - 1.1e-10 40.8 0.5 3.2e-10 39.3 0.2 1.9 1 1 1 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Paralemmin PF03285.10 ETO37003.1 - 0.2 11.1 7.6 0.12 11.8 4.0 1.5 1 1 0 1 1 1 0 Paralemmin DDHD PF02862.12 ETO37003.1 - 0.27 10.9 4.2 0.32 10.7 2.9 1.1 1 0 0 1 1 1 0 DDHD domain Cytochrom_C_2 PF01322.15 ETO37004.1 - 0.087 13.3 3.4 0.23 11.9 0.1 2.9 3 0 0 3 3 3 0 Cytochrome C' WD40 PF00400.27 ETO37005.1 - 1.9e-23 81.4 13.1 4.5e-07 29.5 0.1 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETO37005.1 - 9.2e-06 24.0 2.6 0.032 12.3 0.0 3.5 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETO37005.1 - 0.0087 14.8 4.5 1.1 7.9 0.0 2.4 1 1 1 2 2 2 2 Nup133 N terminal like Clathrin_propel PF01394.15 ETO37005.1 - 0.081 13.2 4.9 0.91 9.9 0.5 3.6 3 0 0 3 3 3 0 Clathrin propeller repeat Trypsin_2 PF13365.1 ETO37006.1 - 4.2e-12 46.1 0.0 5.4e-11 42.5 0.0 2.6 3 0 0 3 3 3 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 ETO37006.1 - 3.4e-11 42.8 0.4 4.4e-06 26.4 0.2 3.3 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.19 ETO37006.1 - 7.5e-06 26.0 0.4 0.038 14.1 0.3 3.5 3 0 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) DNA_pol_B PF00136.16 ETO37006.1 - 0.038 12.7 0.0 0.082 11.6 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase family B SspB PF04386.8 ETO37007.1 - 0.073 12.6 1.4 0.13 11.8 0.6 1.7 2 0 0 2 2 2 0 Stringent starvation protein B RasGEF PF00617.14 ETO37008.1 - 5.3e-53 179.5 3.5 5.4e-53 179.5 1.2 1.9 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 ETO37008.1 - 8.6e-13 48.2 2.6 4.1e-12 46.1 1.8 2.2 1 1 0 1 1 1 1 RasGEF N-terminal motif PUB PF09409.5 ETO37008.1 - 2.6e-09 36.6 0.0 9.4e-09 34.9 0.0 1.9 1 0 0 1 1 1 1 PUB domain RHH_2 PF03693.9 ETO37008.1 - 0.048 13.8 0.1 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0156) Vasculin PF15337.1 ETO37008.1 - 3.8 8.0 7.3 0.48 10.9 0.5 3.0 3 1 0 3 3 3 0 Vascular protein family Vasculin-like 1 SDA1 PF05285.7 ETO37009.1 - 0.49 9.6 4.2 0.84 8.8 2.9 1.3 1 0 0 1 1 1 0 SDA1 Cyt-b5 PF00173.23 ETO37011.1 - 9.2e-10 38.1 0.0 1.3e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ycf1 PF05758.7 ETO37012.1 - 0.00011 20.1 0.7 0.00012 20.0 0.5 1.0 1 0 0 1 1 1 1 Ycf1 Cofilin_ADF PF00241.15 ETO37012.1 - 0.001 18.9 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Mucin PF01456.12 ETO37012.1 - 0.0093 15.7 3.8 0.013 15.2 2.6 1.1 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF1510 PF07423.6 ETO37012.1 - 0.021 14.2 7.2 0.029 13.7 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2146 PF10220.4 ETO37012.1 - 0.023 12.7 2.2 0.028 12.4 1.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Hid1 PF12722.2 ETO37012.1 - 0.18 9.4 3.1 0.2 9.2 2.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MCPVI PF02993.9 ETO37012.1 - 1.7 8.7 9.2 2.5 8.1 6.3 1.2 1 0 0 1 1 1 0 Minor capsid protein VI Saccharop_dh PF03435.13 ETO37013.1 - 2.6e-14 53.0 0.0 2.9e-14 52.8 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 ETO37013.1 - 0.017 15.1 0.0 0.022 14.7 0.0 1.1 1 0 0 1 1 1 0 NADH(P)-binding Cytomega_UL84 PF06284.6 ETO37013.1 - 0.13 10.6 1.7 0.15 10.4 1.2 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein zf-RING_2 PF13639.1 ETO37014.1 - 1.9e-12 46.8 4.7 1.9e-12 46.8 3.2 1.9 1 1 1 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 ETO37014.1 - 1.9e-09 37.4 9.7 5.3e-09 36.0 6.7 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 ETO37014.1 - 7.6e-08 31.8 4.0 7.6e-08 31.8 2.8 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETO37014.1 - 1.6e-07 30.9 3.1 1.6e-07 30.9 2.2 2.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETO37014.1 - 4.4e-07 29.5 5.1 4.4e-07 29.5 3.6 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 ETO37014.1 - 9e-07 28.8 6.0 9e-07 28.8 4.2 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 ETO37014.1 - 1.3e-06 28.1 3.6 1.3e-06 28.1 2.5 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_RING PF05883.6 ETO37014.1 - 0.03 14.1 2.3 0.042 13.6 1.6 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain FANCL_C PF11793.3 ETO37014.1 - 0.036 14.0 5.5 0.26 11.2 3.8 2.3 1 1 1 2 2 2 0 FANCL C-terminal domain TNFR_c6 PF00020.13 ETO37014.1 - 0.061 13.4 1.7 0.061 13.4 1.2 2.2 2 0 0 2 2 2 0 TNFR/NGFR cysteine-rich region stn_TNFRSF12A PF12191.3 ETO37014.1 - 0.11 12.5 0.3 0.15 12.0 0.2 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain zf-RING-like PF08746.6 ETO37014.1 - 0.2 11.7 7.3 3.6 7.6 0.3 2.5 2 0 0 2 2 2 0 RING-like domain zinc-ribbons_6 PF07191.7 ETO37014.1 - 0.3 10.8 5.6 1.1 9.1 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbons zf-Nse PF11789.3 ETO37014.1 - 3.2 7.3 7.0 7.8 6.1 4.8 1.9 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-SNAP50_C PF12251.3 ETO37015.1 - 2.4e-47 160.8 9.7 5.8e-47 159.6 6.7 1.6 1 1 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal zf-Dof PF02701.10 ETO37015.1 - 0.33 10.8 5.6 0.67 9.9 3.9 1.5 1 0 0 1 1 1 0 Dof domain, zinc finger FLO_LFY PF01698.11 ETO37018.1 - 0.53 9.0 11.7 0.6 8.8 8.1 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Daxx PF03344.10 ETO37018.1 - 0.59 8.5 21.3 0.62 8.4 14.8 1.1 1 0 0 1 1 1 0 Daxx Family Secretin_N_2 PF07655.8 ETO37018.1 - 9.6 6.6 26.7 11 6.4 8.8 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain Macoilin PF09726.4 ETO37018.1 - 9.8 4.3 17.8 10 4.2 12.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Aldo_ket_red PF00248.16 ETO37019.1 - 9.7e-23 80.3 0.0 1.5e-18 66.6 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family Aldo_ket_red PF00248.16 ETO37020.1 - 2.2e-21 75.9 0.0 2.7e-21 75.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ABC2_membrane_3 PF12698.2 ETO37021.1 - 0.02 13.9 2.6 0.022 13.8 1.8 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF3870 PF12986.2 ETO37023.1 - 0.42 10.8 6.2 1.6 9.0 0.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3870) zf-CCHC PF00098.18 ETO37024.1 - 0.0021 17.9 5.7 0.0021 17.9 3.9 2.0 2 0 0 2 2 2 1 Zinc knuckle MelC1 PF06236.6 ETO37024.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 NUDIX PF00293.23 ETO37026.1 - 2.1e-11 43.5 0.0 6.2e-11 42.0 0.0 1.8 1 1 0 1 1 1 1 NUDIX domain zf-Di19 PF05605.7 ETO37026.1 - 0.00049 20.1 1.2 0.0012 18.9 0.9 1.7 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding FCP1_C PF09309.5 ETO37027.1 - 0.06 12.6 0.5 0.099 11.9 0.4 1.3 1 0 0 1 1 1 0 FCP1, C-terminal PXB PF12828.2 ETO37028.1 - 0.28 10.7 2.9 0.68 9.5 1.0 2.0 1 1 0 2 2 2 0 PX-associated Thg1C PF14413.1 ETO37029.1 - 0.044 13.4 1.7 0.068 12.8 1.2 1.3 1 0 0 1 1 1 0 Thg1 C terminal domain ApoC-I PF04691.7 ETO37029.1 - 0.14 11.8 0.4 0.14 11.8 0.3 2.0 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) RRM_1 PF00076.17 ETO37030.1 - 2e-33 113.8 1.0 1.2e-17 63.2 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETO37030.1 - 1.1e-25 89.3 0.2 5.5e-12 45.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETO37030.1 - 2.6e-21 75.1 0.3 2.9e-09 36.6 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETO37030.1 - 1.7e-05 24.5 0.1 0.0054 16.4 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 ETO37030.1 - 0.00019 21.1 0.1 0.64 9.7 0.0 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DUF4283 PF14111.1 ETO37030.1 - 0.039 13.0 0.3 4.3 6.4 0.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4283) Cwf_Cwc_15 PF04889.7 ETO37030.1 - 1.4 8.5 45.4 0.12 12.0 6.8 3.5 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein MS_channel PF00924.13 ETO37032.1 - 1.3e-11 44.2 5.3 1.8e-11 43.7 3.7 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_6 PF13405.1 ETO37032.1 - 0.1 12.5 0.0 0.3 11.0 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain SAM_1 PF00536.25 ETO37033.1 - 1.5e-10 41.0 0.6 3e-10 40.0 0.4 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETO37033.1 - 4.2e-09 36.1 0.3 8.5e-09 35.1 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) MIP-T3 PF10243.4 ETO37033.1 - 0.0014 17.2 14.9 0.0017 16.9 10.3 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF1510 PF07423.6 ETO37033.1 - 0.0058 16.0 11.8 0.0096 15.3 8.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Astro_capsid PF03115.9 ETO37033.1 - 0.0063 14.8 2.3 0.0075 14.5 1.6 1.1 1 0 0 1 1 1 1 Astrovirus capsid protein precursor CDC45 PF02724.9 ETO37033.1 - 0.029 12.3 8.4 0.043 11.8 5.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.11 ETO37033.1 - 0.085 12.7 1.6 0.15 11.9 1.1 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DDHD PF02862.12 ETO37033.1 - 0.17 11.6 8.3 0.27 10.9 5.7 1.2 1 0 0 1 1 1 0 DDHD domain Zip PF02535.17 ETO37033.1 - 1.1 8.2 4.5 1.6 7.6 3.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Mem_trans PF03547.13 ETO37033.1 - 2.7 6.1 5.7 0.72 8.0 2.0 1.4 2 0 0 2 2 2 0 Membrane transport protein RR_TM4-6 PF06459.7 ETO37033.1 - 2.8 7.7 12.7 4.1 7.2 8.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GCFC PF07842.7 ETO37035.1 - 6.9e-12 45.2 10.4 5.9e-07 29.1 0.2 2.9 3 0 0 3 3 3 2 GC-rich sequence DNA-binding factor-like protein RAI1 PF08652.6 ETO37037.1 - 0.11 12.3 0.8 0.28 11.0 0.0 2.2 2 0 0 2 2 2 0 RAI1 like PD-(D/E)XK nuclease Pyr_redox_dim PF02852.17 ETO37038.1 - 6.1e-27 93.8 1.1 1.5e-25 89.3 0.4 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 ETO37038.1 - 5.3e-16 58.7 0.1 1.4e-15 57.4 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETO37038.1 - 4.4e-15 56.0 0.0 1.3e-14 54.5 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETO37038.1 - 1.1e-06 28.8 0.0 4.3e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETO37038.1 - 0.00084 18.3 0.0 0.03 13.2 0.0 2.6 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.13 ETO37038.1 - 0.021 14.5 0.1 0.052 13.2 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 ETO37038.1 - 0.028 14.1 0.0 0.062 13.0 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 ETO37038.1 - 0.049 12.7 0.1 0.21 10.7 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.1 ETO37038.1 - 0.063 13.5 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain UDPG_MGDP_dh_N PF03721.9 ETO37038.1 - 0.093 12.0 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Kei1 PF08552.6 ETO37039.1 - 0.044 13.4 0.3 0.53 9.9 0.0 2.1 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 YMF19 PF02326.10 ETO37039.1 - 0.082 13.4 0.8 0.41 11.2 0.0 2.2 2 0 0 2 2 2 0 Plant ATP synthase F0 Neur_chan_memb PF02932.11 ETO37040.1 - 3.8e-06 26.9 12.1 3.4e-05 23.8 5.5 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region CcmH PF03918.9 ETO37040.1 - 0.48 9.3 0.0 0.48 9.3 0.0 1.9 2 0 0 2 2 2 0 Cytochrome C biogenesis protein DUF2339 PF10101.4 ETO37040.1 - 0.7 8.1 12.4 6.8 4.8 8.4 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2339) DUF605 PF04652.11 ETO37041.1 - 0.0011 18.4 3.7 0.0013 18.2 2.6 1.1 1 0 0 1 1 1 1 Vta1 like DUF912 PF06024.7 ETO37041.1 - 0.012 15.5 0.3 0.012 15.5 0.2 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TMEM154 PF15102.1 ETO37041.1 - 0.032 13.9 0.4 0.032 13.9 0.3 1.6 2 0 0 2 2 2 0 TMEM154 protein family Herpes_gE PF02480.11 ETO37041.1 - 0.05 11.8 1.9 0.044 12.0 0.2 1.7 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Orai-1 PF07856.7 ETO37041.1 - 0.1 12.1 4.5 0.18 11.3 3.1 1.3 1 0 0 1 1 1 0 Mediator of CRAC channel activity SKN1 PF03935.10 ETO37041.1 - 0.21 9.6 1.2 0.29 9.2 0.8 1.2 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) DUF4448 PF14610.1 ETO37041.1 - 0.27 10.7 2.1 0.43 10.0 1.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) Ras PF00071.17 ETO37042.1 - 7.3e-41 139.2 8.4 8.6e-35 119.5 0.5 2.5 2 1 1 3 3 3 2 Ras family Miro PF08477.8 ETO37042.1 - 3.2e-18 66.3 0.1 7.8e-18 65.1 0.1 1.7 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETO37042.1 - 6.7e-11 41.7 1.9 2e-10 40.1 0.6 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETO37042.1 - 2.4e-07 30.3 0.5 4e-07 29.6 0.4 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 ETO37042.1 - 0.00026 20.2 0.4 0.00044 19.4 0.3 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 ETO37043.1 - 0.00015 21.2 0.2 0.0013 18.1 0.0 2.2 2 1 0 2 2 2 1 Ras family Acetyltransf_1 PF00583.19 ETO37044.1 - 0.0004 20.3 0.1 0.00073 19.5 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family tRNA-synt_1 PF00133.17 ETO37045.1 - 1.6e-136 455.7 9.8 9.9e-99 330.9 0.0 3.8 4 0 0 4 4 4 3 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 ETO37045.1 - 2.8e-19 69.3 0.1 6.8e-19 68.1 0.1 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 ETO37045.1 - 3.6e-07 29.1 0.1 0.0082 14.8 0.0 3.2 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 ETO37045.1 - 0.0011 18.1 0.0 0.0039 16.3 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain HHH_3 PF12836.2 ETO37045.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif CAF-1_p150 PF11600.3 ETO37046.1 - 0.55 9.5 38.8 0.85 8.9 26.9 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Neur_chan_memb PF02932.11 ETO37046.1 - 3.1 7.6 10.4 5.1 6.9 7.2 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region KOG2701 PF09762.4 ETO37047.1 - 6.7e-47 159.8 0.0 7.4e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein (DUF2037) XPG_N PF00752.12 ETO37049.1 - 0.0096 16.1 0.1 0.68 10.2 0.1 3.0 1 1 0 1 1 1 1 XPG N-terminal domain MtN3_slv PF03083.11 ETO37050.1 - 8.8e-31 105.6 10.0 3.3e-20 71.7 0.4 2.6 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange DUF373 PF04123.8 ETO37050.1 - 0.18 10.8 3.0 0.68 8.9 1.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF373) DUF3987 PF13148.1 ETO37051.1 - 0.036 12.6 0.2 0.045 12.3 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Ribosomal_L5_C PF00673.16 ETO37051.1 - 0.043 13.5 0.1 0.066 12.9 0.1 1.4 1 0 0 1 1 1 0 ribosomal L5P family C-terminus Beach PF02138.13 ETO37053.1 - 6.7e-110 366.7 0.3 1.1e-109 366.0 0.2 1.4 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 ETO37053.1 - 9.4e-13 47.5 6.9 9.7e-10 37.9 0.2 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETO37053.1 - 1.6e-05 23.8 0.2 2.9e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Nup133 N terminal like HAD PF12710.2 ETO37054.1 - 7.9e-18 65.3 0.0 4.3e-17 62.8 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 ETO37054.1 - 1.4e-14 55.0 0.1 1e-05 26.0 0.0 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETO37054.1 - 4.9e-09 36.0 2.2 1.5e-08 34.4 1.1 2.2 2 1 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 ETO37054.1 - 0.0027 17.3 0.2 0.0027 17.3 0.1 3.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Myc_N PF01056.13 ETO37054.1 - 0.038 13.1 6.4 0.062 12.4 4.5 1.2 1 0 0 1 1 1 0 Myc amino-terminal region RR_TM4-6 PF06459.7 ETO37054.1 - 0.13 12.1 12.1 0.29 11.0 8.4 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RP-C_C PF11800.3 ETO37054.1 - 0.36 10.4 7.0 0.7 9.5 4.8 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region Daxx PF03344.10 ETO37054.1 - 0.49 8.8 12.9 0.74 8.2 8.9 1.2 1 0 0 1 1 1 0 Daxx Family E1-E2_ATPase PF00122.15 ETO37055.1 - 0.0016 17.5 0.1 0.0036 16.3 0.0 1.7 2 0 0 2 2 2 1 E1-E2 ATPase RseC_MucC PF04246.7 ETO37055.1 - 0.012 15.1 0.6 1.8 8.1 0.0 2.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC UCH PF00443.24 ETO37056.1 - 5.2e-33 114.2 6.6 5.2e-33 114.2 4.6 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETO37056.1 - 4.5e-14 52.5 6.0 9.7e-14 51.4 4.1 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Hydrolase_like2 PF13246.1 ETO37057.1 - 0.00082 19.2 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit ETRAMP PF09716.5 ETO37058.1 - 1.4 8.8 9.0 3.3 7.7 6.2 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF2681 PF10883.3 ETO37058.1 - 6.2 7.0 9.9 8.9 6.5 2.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2681) EF-hand_9 PF14658.1 ETO37060.1 - 0.069 13.0 0.1 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain Baculo_PEP_C PF04513.7 ETO37061.1 - 0.0055 16.5 0.9 0.014 15.2 0.6 1.6 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1241 PF06840.6 ETO37061.1 - 0.058 12.6 0.8 0.13 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1241) K-box PF01486.12 ETO37061.1 - 1.5 8.6 6.9 6.9 6.5 4.8 1.9 1 1 0 1 1 1 0 K-box region